bluuebunny/crossref_metadata_2025_split huggingface dataset:
Teaching the un-teachable: storytelling and meditation in workplace spirituality courses
Authors: Marques Joan , Kumar Dhiman Satinder , Biberman Jerry 
Published: April 2014

Purpose– The purpose of this paper is to review the implementation of two strategies that are actually un-teachable yet highly effective in higher education: meditation and storytelling.Design/methodology/approach– Specifically focussing on workplace spirituality as a movement from corporate workers, and consequently, also a teaching topic in management education, the paper first indicates some problems faced in today's world, and relates these to the need for facilitating college courses in more compelling and comprehensive ways.Findings– Spirituality and spiritual concepts can involve emotional and other non-cognitive experiences which cannot be taught using traditional teaching approaches such as reading and lecture. Specific approaches, such as meditation and storytelling are useful for teaching spirituality and spiritual concepts in a business school classroom setting. These two strategies provide an opportunity for students to reflect on their experiences and to become more self-aware.Practical implications– Using the practical strategies discussed in this paper in management classes turns out to be a positive experience for both the course facilitators and the students.Originality/value– Reflecting on the overhaul attempts of management education in universities, even those with the prestige of Harvard and Stanford, the authors discuss some interesting strategies that can help management educators take their course experiences and the results attained to the next level.
Temporal Changes in Survival after Cardiac Surgery Are Associated with the Thirty‐Day Mortality Benchmark
Authors: Maxwell Bryan G. , Wong Jim K. , Miller D. Craig , Lobato Robert L. 
Published: April 2014

ObjectiveTo assess the hypothesis that postoperative survival exhibits heterogeneity associated with the timing of quality metrics.Data SourcesRetrospective observational study using the Nationwide Inpatient Sample from 2005 through 2009.Study DesignSurvival analysis was performed on all admission records with a procedure code for major cardiac surgery (n = 595,089). The day‐by‐day hazard function for all‐cause in‐hospital mortality at 1‐day intervals was analyzed using joinpoint regression (a data‐driven method of testing for changes in hazard).Data Extraction MethodsA comprehensive analysis of a publicly available national administrative database was performed.Principal FindingsStatistically significant shifts in the pattern of postoperative mortality occurred at day 6 (95 percent CI = day 5–8) and day 30 (95 percent CI = day 20–35).ConclusionsWhile the shift at day 6 plausibly can be attributed to the separation between routine recovery and a complicated postoperative course, the abrupt increase in mortality at day 30 has no clear organic etiology. This analysis raises the possibility that this observed shift may be related to clinician behavior because of the use of 30‐day mortality as a quality metric, but further studies will be required to establish causality.
Remember that patient you saw last week?
Authors: Gildfind Stephen , Egerton‐Warburton Diana , Craig Simon 
Published: April 2014

AbstractPatient outcome feedback has been defined as ‘the natural process of finding out what happens to one's patients after their evaluation and treatment (in the ED)’. It seems likely that emergency medicine trainees and Fellows will improve their diagnostic accuracy if they increase the frequency with which they find out what happens to their patients. Not only does this allow testing of their own diagnosis with the final diagnosis, but also allows meaningful feedback on therapies commenced in the ED. We believe that seeking outcome feedback should be more actively encouraged by the ACEM training programme.
Roles of Small and Semi‐subsistence Farms in the EU
Authors: Davidova Sophia , Bailey Alastair 
Published: April 2014

SummarySmall and semi‐subsistence farms (SSFs) in the EU play a number of socio‐economic roles. They maintain rural welfare, keep rural areas populated, contribute to the rural non‐farm economy, and provide environmental public goods such as attractive landscapes. Particularly in the New Member States and in the poorer regions of the Southern EU‐15, one of the most important roles of small and SSFs is supporting social and economic welfare, by acting as a ‘safety net’ for poor families. The disappearance of small and SSFs would often mean increased poverty, losses to the rural non‐farm economy, and depopulation, especially in remote areas, and might result in environmental loss. Variation in the importance of small and SSFs across the rural areas in Europe and the complex reality in which small and SSFs are not the only suppliers of ‘joint products’, explain some of the difficulties of designing EU policy for small and SSFs. What appears to be clear is that small farms and SSFs do produce a range of public goods for which, arguably, compensation is justified, and the case for support on welfare grounds is strong. However, the ability of the Common Agricultural Policy budget and its mechanisms to provide effective compensation for the provision of public goods is a matter of some debate.
CAP Reform Proposals for Small and Semi‐subsistence Farms
Authors: Dwyer Janet 
Published: April 2014

SummaryAssessing the ‘new’ CAP after 2013 reveals some positive developments encouraging MAs (Managing Authorities) to recognise the particular characteristics of small and SSFs, in designing and implementing appropriate policy options. Because Pillar I aid is unavoidably linked to scale and many small farms cannot or do not claim it, the financial impact of Pillar I on small and SSFs will remain modest. Nevertheless, more options exist for increasing this impact through explicit or implicit tailoring, where Member States so choose. The Small Farmers Scheme, in particular, offers benefits by reducing transaction costs. For Pillar II, the new framework offers more scope for funding tailored to the specific needs of small and SSF farms, but there is no guarantee that this will translate into more cost‐effective Rural Development Programmes, and there is concern that such developments may be disincentivised by other aspects of the approach. Stronger guidance from the European Commission, as well as support from the European Network for Rural Development, could help Managing Authorities to consider the needs of these farms more fully in Rural Development Programme design. In sum, the ‘new’ CAP offers greater potential to support and enhance the value of Europe's small and SSFs than its predecessor. Ultimately, much depends upon choices made at national or regional levels, given the considerable range of options now available.
Youth tobacco use type and associations with substance use disorders
Authors: Cavazos‐Rehg Patricia A. , Krauss Melissa J. , Spitznagel Edward L. , Grucza Richard A. , Bierut Laura Jean 
Published: April 2014

AbstractAimsTo examine the associations between youth poly‐tobacco use and substance use disorders.DesignAnalysis of data from the 2007–11USNational Survey on Drug Use and Health.SettingRandomly selected, household‐dwelling adolescents from the non‐institutionalized, civilian population of theUnited States.ParticipantsA total of 91 152 adolescents (aged 12–17 years).MethodsLogistic regression models were used to examine the associations between type of tobacco user (non‐user, users of alternative tobacco products only, users of cigarettes only and users of cigarettes plus alternative tobacco products) with past year alcohol, marijuana or other illicit drug use disorders, adjusting for demographic and social variables.FindingsCompared with non‐users of tobacco, the greatest risk for substance use disorders was among users of cigarettes plus alternative tobacco products [alcohol disorder adjusted odds ratio (aOR) = 18.3, 95% confidence interval (CI) = 16.2–20.6; marijuana disorder aOR = 37.2, 95%CI = 32.5–42.7; other drug disorder aOR = 18.4, 95%CI = 15.4–21.8], followed by users of cigarettes only (alcohol disorder aOR = 9.6, 95%CI = 8.8–10.6; marijuana disorder aOR = 20.4, 95%CI = 18.1–23.0; other drug disorder aOR = 9.4, 95%CI = 7.8–11.4), then users of alternative tobacco products only (alcohol disorder aOR = 8.1, 95%CI = 6.7–9.6; marijuana disorder aOR = 9.2, 95%CI = 7.5–11.4; other drug disorder aOR = 3.2, 95%CI = 2.4–4.3).ConclusionsTobacco use in adolescence is associated with higher rates of substance use disorders across all tobacco users, especially among those who use cigarettes plus other tobacco products.
Circadian intraocular pressure patterns in healthy subjects, primary open angle and normal tension glaucoma patients with a contact lens sensor
Authors: Agnifili Luca , Mastropasqua Rodolfo , Frezzotti Paolo , Fasanella Vincenzo , Motolese Ilaria , Pedrotti Emilio , Iorio Angelo Di , Mattei Peter A. , Motolese Eduardo , Mastropasqua Leonardo 
Published: April 2014

AbstractPurposeTo examine the circadian intraocular pressure (IOP) patterns in healthy subjects, in primary open angle and normal tension glaucoma (POAG; NTG) using a contact lens sensor (CLS; Sensimed Triggerfish, Lausanne, Switzerland).MethodsThis was an observational, nonrandomized study. Ten healthy subjects (Group 1, 10 eyes) and 20 glaucomatous patients [20 eyes, 10 with POAG (Group 2) and 10 with NTG (Group 3)] were enrolled. All patients were controlled with prostaglandin analogues. The 24‐hr IOP pattern was the main outcome. The morning (6AM–11AM), afternoon/evening (noon‐11PM) and night (midnight‐5AM) subperiod patterns, peaks and prolonged peaks (>1 hr) were secondary outcomes.ResultsMean 24‐hr IOP pattern showed a nocturnal acrophase in all groups. Patterns were significantly different among groups (p = 0.02), with highest nocturnal IOP values in POAG. Prolonged peaks were more common in patients with glaucoma (70%) than in healthy subjects (33.3%) (p < 0.001). Significant differences were found for Groups 2 and 3 in the morning versus afternoon/evening (p = 0.019 and p = 0.035, Bonferroni correction), morning versus night (p = 0.005 and p < 0.0001) and afternoon/evening versus night periods comparisons (p < 0.0001 for both groups). In Group 1, patterns significantly differed in the morning versus night and afternoon/evening versus night period comparisons (p < 0.0001).ConclusionsContinuous 24‐hr IOP monitoring with the CLS revealed a nocturnal acrophase in healthy subjects and, more markedly, in glaucoma. Because the diurnal IOP profile seems not to predict the nocturnal rhythm, the circadian IOP pattern should be evaluated in clinical practice. These findings may be worthwhile for the management of glaucoma.
Pertussis is still common in a highly vaccinated infant population
Authors: Berti Elettra , Chiappini Elena , Orlandini Elisa , Galli Luisa , de Martino Maurizio 
Published: April 2014

AbstractAimTo provide epidemiological data on pertussis in a highly vaccinated paediatric population, focusing on the age of the infected children.MethodsWe analysed data from the regional hospital discharge database on children hospitalised for pertussis in Tuscany, Italy, from January 2000 to December 2012.ResultsA total of 279 cases were recorded. The majority of hospitalised children were infants (75.6%), who had the highest rate of complications (24.2%) of any age group and a crude mortality rate of 9.47 per 1000. The overall hospitalisation rate decreased significantly during the study period, from 4.23 to 2.82 per 100 000, but when we analysed the data by age groups, we found notable differences. Hospitalisation rates in the 1‐ to 4‐year‐old age group decreased significantly from 2.82 in the year 2000 to zero per 100 000 in 2012 and decreased significantly in the 5‐ to 9‐year‐old age group over the same period, from 6.58 to 0.63 per 100 000. Overall hospitalisation rates in the infant group remained high at 53.14 per 100 000, with three peaks due to periodic pertussis outbreaks.ConclusionPertussis is still a relevant health concern in infants who are unvaccinated or incompletely immunised, both in terms of morbidity and mortality.
Effects of genetic and environmental factors on muscle glycogen content in Japanese Black cattle
Authors: Komatsu Tomohiko , Shoji Noriaki , Saito Kunihiko , Suzuki Keiichi 
Published: April 2014

AbstractMonosaccharides such as glucose contribute to the development of meat flavor upon heating via the Maillard reaction; therefore, monosaccharide content is related to beef palatability. Here, we analyzed the effects of genetic and environmental factors on the content of glycogen, one of the precursors of monosaccharides, in the muscles of 958 fattened Japanese Black cattle from Yamagata Prefecture. Analysis of variance showed that muscle glycogen content was affected by the farm and postmortem periods, but not by sex, slaughter age, slaughter month or number of days detained at the slaughter yard. Additionally, consumption of digestible brown rice feed elevated muscle glycogen levels. Glycogen heritability was estimated to be 0.34, and genetic correlations between glycogen and carcass weight (CW) or beef marbling standard (BMS) were weak. The predicted breeding values varied among paternal lines. These results demonstrated that genetic factors might improve muscle glycogen content and therefore beef palatability, but do not influence CW or BMS.
Multivariate time‐dependent comparison of the impact of lenalidomide in lower‐risk myelodysplastic syndromes with chromosome 5q deletion
Authors: Sánchez‐García Joaquín , del Cañizo Consuelo , Lorenzo Ignacio , Nomdedeu Benet , Luño Elisa , de Paz Raquel , Xicoy Blanca , Valcárcel David , Brunet Salut , Marco‐Betes Victor , García‐Pintos Marta , Osorio Santiago , Tormo Mar , Bailén Alicia , Cerveró Carlos , Ramos Fernando , Diez‐Campelo María , Such Esperanza , Arrizabalaga Beatriz , Azaceta Gemma , Bargay Joan , Arilla María J. , Falantes José , Serrano‐López Josefina , Sanz Guillermo F. ,   the Spanish Group on Myelodysplastic Syndromes (GES MD)
Published: April 2014

SummaryThe impact of lenalidomide treatment on long‐term outcomes of patients with lower risk myelodysplastic syndromes (MDS) and chromosome 5q deletion (del(5q)) is unclear. This study used time‐dependent multivariate methodology to analyse the influence of lenalidomide therapy on overall survival (OS) and acute myeloblastic leukaemia (AML) progression in 215 patients with International Prognostic Scoring System (IPSS) low or intermediate‐1 risk and del(5q). There were significant differences in several relevant characteristics at presentation between patients receiving (n = 86) or not receiving lenalidomide (n = 129). The 5‐year time‐dependent probabilities of OS and progression to AML were 62% and 31% for patients receiving lenalidomide and 42% and 25% for patients not receiving lenalidomide; differences were not statistically significant in multivariate analysis that included all variables independently associated with those outcomes (OS, P = 0·45; risk of AML, P = 0·31, respectively). Achievement of RBC transfusion independency (P = 0·069) or cytogenetic response (P = 0·021) after lenalidomide was associated with longer OS in multivariate analysis. These data clearly show that response to lenalidomide results in a substantial clinical benefit in lower risk MDS patients with del(5q). Lenalidomide treatment does not appear to increase AML risk in this population of patients.
Phase II trial of nanoparticle albumin‐bound paclitaxel as second‐line chemotherapy for unresectable or recurrent gastric cancer
Authors: Sasaki Yasutsuna , Nishina Tomohiro , Yasui Hirofumi , Goto Masahiro , Muro Kei , Tsuji Akihito , Koizumi Wasaburo , Toh Yasushi , Hara Takuo , Miyata Yoshinori 
Published: April 2014

This multicenter phase II study first investigated the efficacy and safety of nanoparticle albumin‐bound paclitaxel (nab‐paclitaxel) when given every 3 weeks to patients with unresectable or recurrent gastric cancer who had received a prior round of fluoropyrimidine‐containing chemotherapy. Patients with unresectable or recurrent gastric cancer who experienced progression despite fluoropyrimidine‐containing treatment were studied. Nab‐paclitaxel was given i.v. at 260 mg/m2 on day 1 of each 21‐day cycle without anti‐allergic premedication until disease progression or study discontinuation. The primary endpoint was the overall response rate. The secondary endpoints were the disease control rate, progression‐free survival, overall survival, and safety. From April 2008 to July 2010, 56 patients were enrolled, 55 patients received the study treatment, and 54 patients were evaluable for responses. According to an independent review committee, the overall response rate was 27.8% (15/54; 95% confidence interval [CI], 16.5–41.6) and the disease control rate was 59.3% (32/54; 95% CI, 45.0–72.4). One patient had a complete response. The median progression‐free survival and overall survival were 2.9 months (95% CI, 2.4–3.6) and 9.2 months (95% CI, 6.9–11.4), respectively. The most common grade 3/4 toxicities were neutropenia (49.1%), leucopenia (20.0%), lymphopenia (10.9%), and peripheral sensory neuropathy (23.6%). There were no treatment‐related deaths. Nab‐paclitaxel, given every 3 weeks, showed promising activity against previously treated unresectable or recurrent gastric cancers, with well‐tolerated toxicities. (Trial registration, ClinicalTrials.gov: NCT00661167).
Owners of the Map: Mobility and Mobilization among Motorcycle Taxi Drivers in Bangkok
Authors: SOPRANZETTI CLAUDIO 
Published: April 2014

AbstractIn this article, I discuss the connection between spatial mobility and political mobilization among motorcycle taxi drivers during the 2010 protests in Bangkok. Through the study of their multiple roles, both as transport operators and as political mobilizers, I explore the nexus of mobility and mobilization and analyze motorcycle taxi drivers as central political actors in contemporary Thailand. In this sense, the article focuses on investigating the historical emergence of “technique of mobilization” based on modulation and control over mobility. I analyze acts of disruption of movement along major infrastructures as moments of time‐space modulation as well as transformative strategies that set in motion alternative messages and configure new modalities of political mobilization. Focusing on such techniques, both in the 2010 Red Shirts protest and in other Thai political mobilizations, I explore the solidification of spaces of mobility as major political arenas for political struggles in contemporary Thailand.
Small‐diameter titanium Grade IV and titanium–zirconium implants in edentulous mandibles: three‐year results from a double‐blind, randomized controlled trial
Authors: Quirynen Marc , Al‐Nawas Bilal , Meijer Henny J.A. , Razavi Amir , Reichert Torsten E. , Schimmel Martin , Storelli Stefano , Romeo Eugenio ,   the Roxolid Study Group
Published: April 2014

AbstractObjectiveThe aim of this study was to compare crestal bone‐level changes, soft tissue parameters and implant success and survival between small‐diameter implants made of titanium/zirconium (TiZr) alloy or of Grade IV titanium (Ti) in edentulous mandibles restored with removable overdentures.Materials and MethodsThis was a randomized, controlled, double‐blind, split‐mouth multicenter clinical trial. Patients with edentulous mandibles received two Straumann bone‐level implants (diameter 3.3 mm), one of Ti Grade IV (control) and one of TiZr (test), in the interforaminal region. Implants were loaded after 6–8 weeks and removable Locator‐retained overdentures were placed within 2 weeks of loading. Modified plaque and sulcus bleeding indices, radiographic bone level, and implant survival and success were evaluated up to 36 months.ResultsOf 91 treated patients, 75 completed the three‐year follow‐up. Three implants were lost (two control and one test implant). The survival rates were 98.7% and 97.3%, and the mean marginal bone level change was −0.78 ± 0.75 and −0.60 ± 0.71 mm for TiZr and Ti Grade IV implants. Most patients had a plaque score of 0 or 1 (54% for test and 51.7% for control), and a sulcus bleeding score of 0 (46.1% for test and 44.9% for control). No significant differences were found between the two implant types for bone‐level change, soft tissue parameters, survival and success.ConclusionsAfter 36 months, similar outcomes were found between Ti Grade IV and TiZr implants. The results confirm that the results seen at 12 months continue over time.
Neural oscillations during non‐rapid eye movement sleep as biomarkers of circuit dysfunction in schizophrenia
Authors: Gardner Richard J. , Kersanté Flavie , Jones Matthew W. , Bartsch Ullrich 
Published: April 2014

AbstractThe neurophysiology of non‐rapid eye movement sleep is characterized by the occurrence of neural network oscillations with distinct origins and frequencies, which act in concert to support sleep‐dependent information processing. Thalamocortical circuits generate slow (0.25–4 Hz) oscillations reflecting synchronized temporal windows of cortical activity, whereas concurrent waxing and waning spindle oscillations (8–15 Hz) act to facilitate cortical plasticity. Meanwhile, fast (140–200 Hz) and brief (< 200 ms) hippocampal ripple oscillations are associated with the reactivation of neural assemblies recruited during prior wakefulness. The extent of the forebrain areas engaged by these oscillations, and the variety of cellular and synaptic mechanisms involved, make them sensitive assays of distributed network function. Each of these three oscillations makes crucial contributions to the offline memory consolidation processes supported by non‐rapid eye movement sleep. Slow, spindle and ripple oscillations are therefore potential surrogates of cognitive function and may be used as diagnostic measures in a range of brain diseases. We review the evidence for disrupted slow, spindle and ripple oscillations in schizophrenia, linking pathophysiological mechanisms to the functional impact of these neurophysiological changes and drawing links with the cognitive symptoms that accompany this condition. Finally, we discuss potential therapies that may normalize the coordinated activity of these three oscillations in order to restore healthy cognitive function.