bluuebunny/crossref_metadata_2025_split huggingface dataset:
Feasibility and efficacy of a novel audiovisual tool to increase colorectal cancer screening among rural Appalachian Kentucky adults
Authors: Kruse-Diehr Aaron J. , Cegelka Derek , Holtsclaw Elizabeth , Edward Jean S. , Vos Sarah C. , Karrer Melissa , Bathje Katie , Rogers Melinda , Russell Elaine , Knight Jennifer Redmond 
Published: July 2024

IntroductionResidents of Appalachian regions in Kentucky experience increased colorectal cancer (CRC) incidence and mortality. While population-based screening methods, such as fecal immunochemical tests (FITs), can reduce many screening barriers, written instructions to complete FIT can be challenging for some individuals. We developed a novel audiovisual tool (“talking card”) to educate and motivate accurate FIT completion and assessed its feasibility, acceptability, and efficacy.Materials and methodsWe collected data on the talking card via: (1) cross-sectional surveys exploring perceptions of images, messaging, and perceived utility; (2) follow-up focus groups centered on feasibility and acceptability; and (3) efficacy testing in community-based FIT distribution events, where we assessed FIT completion rate, number of positive vs. negative screens, demographic characteristics of participants, and primary drivers of FIT completion.ResultsAcross the three study phases, 692 individuals participated. Survey respondents positively identified with the card’s sounds and images, found it highly acceptable, and reported high-to-very high self-efficacy and response efficacy for completing FIT, with nearly half noting greater likelihood to complete screening after using the tool. Focus group participants confirmed the acceptability of the individuals featured on the card. Nearly 75% of participants provided a FIT accurately completed it, with most indicating the talking card, either alone or combined with another strategy, helped with completion.DiscussionTo reduce CRC screening disparities among Appalachian Kentuckians, population-based screening using contextually relevant implementation strategies must be used alongside clinic-based education. The talking card represents a novel and promising strategy to promote screening uptake in both clinical and community settings.
Centella asiatica and its caffeoylquinic acid and triterpene constituents increase dendritic arborization of mouse primary hippocampal neurons and improve age-related locomotion deficits in Drosophila
Authors: Rowe Karon , Gray Nora E. , Zweig Jonathan A. , Law Alexander , Techen Natascha , Maier Claudia S. , Soumyanath Amala , Kretzschmar Doris 
Published: July 2024

IntroductionCentella asiatica (CA) is known in Ayurvedic medicine as a rejuvenating herb with particular benefits in the nervous system. Two groups of specialized metabolites found in CA and purported to contribute to its beneficial effects are triterpenes (TTs) and caffeoylquinic acids (CQAs). In order to evaluate the role and interactions of TTs and CQAs in the effects of CA, we examined the neurotrophic effects of a water extract of CA (CAW) and combinations of its TT and CQA components in mouse primary hippocampal neurons in vitro and in Drosophila melanogaster flies in vivo.MethodsPrimary hippocampal neurons were isolated from mouse embryos and exposed in vitro for 5 days to CAW (50 μg/mL), mixtures of TTs, CQAs or TT + CQA components or to 4 TTs or 8 individual CQA compounds of CAW. Dendritic arborization was evaluated using Sholl analysis. Drosophila flies were aged to 28 days and treated for 2 weeks with CAW (10 mg/mL) in the food, mixtures of TTs, CQAs or TT + CQA and individual TT and CQA compounds. TTs and CQAs were tested at concentrations matching their levels in the CAW treatment used. After 2 weeks of treatment, Drosophila aged 42 days were evaluated for phototaxis responses.ResultsIn mouse primary hippocampal neurons, CAW (50 μg/mL), the TT mix, CQA mix, all individual TTs and most CQAs significantly increased dendritic arborization to greater than control levels. However, the TT + CQA combination significantly decreased dendritic arborization. In Drosophila, a marked age-related decline in fast phototaxis response was observed in both males and females over a 60 days period. However, resilience to this decline was afforded in both male and female flies by treatment from 28 days onwards with CAW (10 mg/mL), or equivalent concentrations of mixed TTs, mixed CQAs and a TT + CQA mix. Of all the individual compounds, only 1,5-diCQA slowed age-related decline in phototaxis in male and female flies.DiscussionThis study confirmed the ability of CAW to increase mouse neuronal dendritic arborization, and to provide resilience to age-related neurological decline in Drosophila. The TT and CQA components both contribute to these effects but do not have a synergistic effect. While individual TTs and most individual CQAs increased dendritic arborization at CAW equivalent concentrations, in the Drosophila model, only 1,5-diCQA was able to slow down the age-related decline in phototaxis. This suggests that combinations (or potentially higher concentrations) of the other compounds are needed to provide resilience in this model.
Modeling transmission of avian influenza viruses at the human-animal-environment interface in Cuba
Authors: Montano Valle Damarys de las Nieves , Berezowski John , Delgado-Hernández Beatriz , Hernández Adrian Quintana , Percedo-Abreu María Irian , Alfonso Pastor , Carmo Luis Pedro 
Published: July 2024

IntroductionThe increasing geographical spread of highly pathogenic avian influenza viruses (HPAIVs) is of global concern due to the underlying zoonotic and pandemic potential of the virus and its economic impact. An integrated One Health model was developed to estimate the likelihood of Avian Influenza (AI) introduction and transmission in Cuba, which will help inform and strengthen risk-based surveillance activities.Materials and methodsThe spatial resolution used for the model was the smallest administrative district (“Consejo Popular”). The model was parameterised for transmission from wild birds to poultry and pigs (commercial and backyard) and then to humans. The model includes parameters such as risk factors for the introduction and transmission of AI into Cuba, animal and human population densities; contact intensity and a transmission parameter (β).ResultsAreas with a higher risk of AI transmission were identified for each species and type of production system. Some variability was observed in the distribution of areas estimated to have a higher probability of AI introduction and transmission. In particular, the south-western and eastern regions of Cuba were highlighted as areas with the highest risk of transmission.DiscussionThese results are potentially useful for refining existing criteria for the selection of farms for active surveillance, which could improve the ability to detect positive cases. The model results could contribute to the design of an integrated One Health risk-based surveillance system for AI in Cuba. In addition, the model identified geographical regions of particular importance where resources could be targeted to strengthen biosecurity and early warning surveillance.
Metabolomics analysis of the effect of GnRH on the pregnancy rate of ewes with estrus synchronization scheme based on progesterone
Authors: Zhang Jing , Sun Shuyuan , Bai Xinyu , Yang Nana , Liu Yiyong , Wu Xinglong , Li Xiangyun 
Published: July 2024

IntroductionGonadotropin-releasing hormone (GnRH) is widely used in the timed artificial insemination protocol for sheep. However, there remains a debate regarding its impact on pregnancy rates during artificial insemination. This study aims to evaluate the effect of GnRH on the pregnancy rates in Huyang ewes, analyze the pre-implantation metabolite changes caused by GnRH using metabolomics, and elucidate the mechanism effect on pregnancy rates.MethodsAll ewes were administered a vaginal progesterone sponge containing 45 mg of flurogestone acetate for 12 days and received 330 units of equine chorionic gonadotropin (eCG) intramuscularly after sponge removal. The experimental group (n = 69) received an intramuscular treatment of 17 μg GnRH agonist triptorelin 48 h after sponge removal on Day 0, while the control group (n = 41) received 1 mL of sterile saline solution. All ewes underwent a single vaginal insemination 58 h after the withdrawal of the progesterone sponge. The difference in pregnancy rates between the two groups was calculated. Metabolomic analysis was performed on plasma samples collected on Day 7 after the treatment of GnRH agonist.ResultsGonadotropin-releasing hormone (GnRH) treatment significantly reduced the pregnancy rate in the experimental group compared with the control group (72.2 vs. 82.9%, p &lt; 0.05). Metabolomic analysis indicated that GnRH treatment affected metabolites involved in collagen synthesis and prostaglandin synthesis in the endometrial tissue, which includes a marked decrease in hydroxyproline amino acid content and a significant increase in corticosterone and prostaglandin D2 lipids and unsaturated fatty acids.ConclusionIn summary, the injection of GnRH agonist Triptorelin 48 h after progesterone sponges removal reduces the pregnancy rate of Huyang ewe following artificial insemination. It also affects the metabolite levels related to endometrial collagen and prostaglandin synthesis, harming embryo implantation.
Fractional Hermite–Hadamard–Mercer-Type Inequalities for Interval-Valued Convex Stochastic Processes with Center-Radius Order and Their Related Applications in Entropy and Information Theory
Authors: Shah Ahsan Fareed , Özcan Serap , Vivas-Cortez Miguel , Saleem Muhammad Shoaib , Kashuri Artion 
Published: July 2024

We propose a new definition of the γ-convex stochastic processes (CSP) using center and radius (CR) order with the notion of interval valued functions (C.RI.V). By utilizing this definition and Mean-Square Fractional Integrals, we generalize fractional Hermite–Hadamard–Mercer-type inclusions for generalized C.RI.V versions of convex, tgs-convex, P-convex, exponential-type convex, Godunova–Levin convex, s-convex, Godunova–Levin s-convex, h-convex, n-polynomial convex, and fractional n-polynomial (CSP). Also, our work uses interesting examples of C.RI.V(CSP) with Python-programmed graphs to validate our findings using an extension of Mercer’s inclusions with applications related to entropy and information theory.
De la majorité absolue à un tiers des voix, le chemin parcouru par le SPÖ depuis Bruno Kreisky
Authors: Matzner Egon 
Published: July 2024

Die SPÖ hat innerhalb von 20 Jahren 900 000 Wählerinnen verloren. Was sind die Gründe für den Niedergang von der führenden politischen Reformkraft zu einer von drei Mittelparteien ? Die Partei hat ihre Fähigkeit zur moralischen Initiative durch illegale und legale Bereicherung schwer beeinträchtigt. Sie hat die Fähigkeit zur geistigen Initiative weitgehend eingebüßt, weil sie mehr und mehr Menschen anzieht, denen es um Erzielung von Einkommen geht, und die nicht an politischen Reformen interessiert sind. In der Praxis ist es zu einer fast vollständigen Akzeptanz der neoliberalen Doktrin durch die österreichische wie durch die anderen europäischen Sozialdemokratien gekommen. Nach der Integration in die EU hat die SPÖ die Neutralitätspolitik des Landes aufgegeben und so ohne Not auf eine außenpolitische Trumpfkarte verzichtet. Die Partei hat keine eigene Programmatik nach dem Sturz des Kommunismus in den osteuropäischen Ländern entwickelt. Der Rückgriff auf eine Politik der «neuen Mitte», wie sie von New Labour und Gerhard Schröder vertreten wird, ist keine überzeugende sozialpolitische Antwort auf die Probleme unserer Zeit, sondern eine Abdankung vor dem neoliberalen Zeitgeist.
Die SPÖ muß wieder ein überzeugendes politischen und demokratisches Reformprogramm entwickeln, ihre Identität stärker herausarbeiten und nicht zögern, sich dem Zeitgeist entgegenzustellen, wenn sie politisch eine Zukunft haben will.
Rezzori et la France
Authors: Ravy Gilbert 
Published: July 2024

Das Thema „Rezzori und Frankreich“ wird hier in zwei gegenseitigen Perspektiven behandelt : zum einen geht es um die Rezeption des Autors Rezzori in Frankreich, insbesondere in der französischen Presse, zum anderen um die Art, wie Rezzori, der lange Jahre in Frankreich verbracht hat, dieses Land und seine Bewohner sieht, beurteilt und in seinem Werk darstellt.
Die Rezeption der zwischen 1961 und 1997 ins Französische übersetzten Romane Rezzoris in Frankreich ist durch zwei Hauptbegriffe charakterisiert : er sei einerseits der typische „ironische Aristokrat“ mit Witz, eleganter Feder und kritischer Distanz, andererseits der letzte Repräsentant der nun (leider?!) versunkenen Habsburger Monarchie, der uns in seinem Werk die letzten Augenblicke eines (Mittel)Europa der Toleranz und des friedlichen Zusammenlebens von diversen Völkern und Religionen wieder lebendig mache.
Der zweite Teil des Beitrags bezieht sich auf den Roman Der Tod meines Bruders Abel sowie auf die beiden unter dem Titel Frankreich 1992 bzw. 1997 erschienenen Essays. Darin lässt sich feststellen, wie paradox Rezzoris Beziehung zu Frankreich sein mag. In Frankreich findet er nämlich gerade das, was er andernorts in Europa vermisst, gerade das, was in seinen Augen die „westliche Kultur“ ausmachte und 1938 zugrundegegangen ist. Aber das „Kulturland Frankreich“ ist und bleibt auch ein jedem noch so wohlwollend gesinnten Fremden hermetisch geschlossenes Land, eine in ihrer Geschichte, in ihrer Kultur, in ihrer Selbstgefälligkeit erstarrte Welt und Gesellschaft, in der trotz vielbeschworener Gleichheit aller Bürger, jeder Einzelne in seiner eigenen, wohlverwahrten, unverrückbar festen Welt lebt. An zwei Hauptbegriffen, die Frankreichs Mentalität und Geschichte prägen, nimmt Rezzori besonders Anstoss : an einem stets wieder erwachenden Nationalismus und an einem nie nachlassenden Rationalismus.
Trotz aller oft sehr akuten (und ebenso oft eindeutig klischeehaften) Kritik bleibt Rezzoris Beziehung zu Frankreich ambivalent: der von ihm heftig gerügten Selbstgefälligkeit der Franzosen und wachsenden Erstarrung ihrer Gesellschaft und Kultur entspricht doch letzten Endes in seinen Augen ein Positives, nämlich die Fähigkeit, der drohenden Globalisierung aller Kultur Widerstand zu leisten.
Figures du dégoût chez Michael Haneke
Authors: Blümlinger Christa 
Published: July 2024

Figuren des Ekels bei Michael Haneke
Die Unzerstörbarkeit der von Freud benannten zivilisatorischen Ekelschranken ist Grundlage der Filme von Michael Haneke, darin den Provokationen der Wiener Aktionisten nicht unverwandt : Beide zielen auf Transgression ab, und zwar über das Motiv des Degoutanten, gebunden an elementare Akte und Materien des Körpers. Der ambivalente Einsatz der Figur des Ekels erzeugt ein Spannungsfeld zwischen Abstoßung und Attraktion und bei Haneke insbesondere eine Mischung von Urteil und Affekt. Der Konflikt zwischen den Ansprüchen der symbolischen Ordnung und der Insistenz der abjekten Lust, wie ihn Julia Kristeva beschreibt, wird hier nicht nur auf der Ebene der filmischen Erzählung manifest, sondern vermittelt sich auch über die formale Gestaltung, etwa über Bildkomposition und Montage.
Motricidad orofacial para reducir el retraso simple del lenguaje en los estudiantes de segundo grado de educación básica
Authors: Aguilar Verdezoto Daniela 
Published: July 2024

La motricidad orofacial se encarga de trabajar con los órganos fono articulatorios, es decir, con la estructura de la cara y sus músculos en general, favoreciendo así el desarrollo del lenguaje. La presente investigación se ejecuta en base de su objetivo, que es proponer la motricidad orofacial para reducir el retraso simple del lenguaje en los estudiantes de EGB. Se desarrolló una investigación de carácter documental con enfoque cualitativo y método de observación indirecta, Con respecto a los resultados alcanzados, se pudo evidenciar que la COVID-19 trajo consecuencias en la educación y en el ámbito familiar de cada alumnado, repercutiendo así en su nivel lingüístico. Según datos de la Unicef Ecuador un 70% afirmó que está aprendiendo menos que antes del confinamiento y a su vez el Ministerio de Educación confirmó que existen problemas de lenguaje en los niños tras la pandemia, lo que dio como resultados desfases en las habilidades articulatorias y comunicativas. Por ello, se consideró oportuno incentivar el uso de praxias faciales a manera de actividades cortas, precisas y dinámicas que garanticen significativamente una mejora en la expresión comunicativa y corporal del alumnado y a su vez el uso de la tecnología como un recurso favorecedor
Particle patterning diversity achieved by a PZT device with different experimental configurations
Authors: Hu Luoke , Li Xianbin , Leng Longlong , Qian Jingui , Wang Yong 
Published: July 2024

Abstract
The acoustofluidic manipulation of particles/cells has gained significant attention in biomedical applications. Conventional acoustofluidics based on surface acoustic waves (SAWs) require accessing cleanroom facilities and expensive lithography equipment to fabricate the interdigital electrodes, limiting their popularity in applications. In this paper, we proposed a low-cost and accessible lead zirconate titanate (PZT) device combined with glass to generate particle patterns. We have achieved diversified particle patterns including annular and honeycombed shapes either on the PZT device surface or on the glass by coupling acoustic waves into the glass using the ultrasonic gel, and showed that the size and shape of the particle pattern unit could be adjusted by changing the harmonics mode frequency or experimental configurations. The formation mechanisms of particle patterns were analyzed through the simulation of acoustic pressure fields. Additionally, we demonstrated the harmless acoustothermal heating (below 37 °C) to the activity of biological samples at the driving voltage of acoustofluidics.
Atlante Elettorale della Società Italiana di Studi Elettorali (SISE) Elezioni Europee 2024
Authors: Società Italiana di Studi Elettorali (SISE)  
Published: July 2024

Questi articoli sono stati pubblicati dal 26 aprile al 7 giugno all’interno del progetto Atlante elettorale della Società Italiana di Studi Elettorali (Sise) che - in collaborazione con Repubblica - offriva ai lettori una serie di uscite settimanali in vista delle elezioni europee dell'8-9 giugno 2024. L’ultimo è ovviamente uscito nell’immediato post-voto.
Il coordinamento scientifico ed editoriale del progetto è stato curato da: Luigi Ceccarini (Università degli Studi di Urbino); Marino de Luca (Università della Calabria); Chiara Fiorelli (Università di Roma La Sapienza); Paolo Natale (Università degli Studi di Milano); Fulvio Venturino (Università degli Studi di Cagliari); Antonella Seddone (Università degli Studi di Torino).
Unofficial Cults of Women in the Serbian Orthodox Church. The Example of the Nun Stefanida of Skadar, Bitola and Dečani
Authors: Gapska Dominika 
Published: July 2024

The paper is focused on a corpus of hymnographic texts dedicated to nun Stefanida/Stevka as an example of a literary work focused on the promotion of a newly revealed saint by the Serbian Orthodox Church, whose role is to elevate the spiritual essence of a society that underwent secularization during the socialist era, while revisiting the core principles of this society’s ideological resilience. By using means of expression, such as modern language (vernacular), fragments of Stevka’s letters, and Serbian cultural and religious topoi, the authors of the hymnographic texts made them more accessible to the contemporary believer. Additionally, the hymnographic texts symbolically represent the spiritual landscape of both past and contemporary Serbia, adding to a more comprehensive narrative about the historical cohesion of the Serbian Orthodox Church.
Pengaruh Kemandirian Keuangan dan Kinerja Keuangan Terhadap Keberlanjutan Keuangan (Financial Sustainability) Pada Pemerintah Kota Yogyakarta
Authors: Miftahurrohman Arif , Putra Prasetya Bangun 
Published: July 2024

Pemerintah daerah memiliki tanggung jawab yang besar dalam memberikan pelayanan kepada masyarakat dengan memperhatikan kondisi keuangan pemerintah daerah. Dimana kondisi keuangan yang baik jika kondisi keuangannya yang berkelanjutan. Penelitian ini bertujuan untuk mengetahui pengaruh kemandirian keuangan dan kinerja keuangan terhadap keberlanjutan keuangan (financial sustainability rasio) pada Pemerintah Kota Yogyakarta. Periode dalam penelitian ini adalah tahun 2013 sampai 2022. Penelitian ini menggunakan pendekatan kuantitatif. Populasi penelitian meliputi Pemerintah Kota Yogyakarta dengan periode pengamatan 2013 sampai 2022. Teknik pemilihan sampel menggunakan metode purposive sampling. Metode analisis data yang digunakan adalah uji hipotesis. Hasil penelitian menunjukkan bahwa Kemandirian Keuangan dan Kinerja Keuangan berpengaruh signifikan terhadap Financial Sustainability Ratio.
Study of Particle Acceleration Using Fine Structures and Oscillations in Microwaves from the Electron Cyclotron Maser
Authors: Sharma Rohit , Battaglia Marina , Yu 余 Sijie 思捷 , Chen 陈 Bin 彬 , Luo 骆 Yingjie 英杰 , Krucker Säm 
Published: July 2024

Abstract
The accelerated electrons during solar flares produce radio bursts and nonthermal X-ray signatures. The quasi-periodic pulsations (QPPs) and fine structures in spatial–spectral–temporal space in radio bursts depend on the emission mechanism and the local conditions, such as magnetic fields, electron density, and pitch-angle distribution. Radio burst observations with high-frequency time resolution imaging provide excellent diagnostics. In converging magnetic field geometries, the radio bursts can be produced via the electron cyclotron maser (ECM). Recently, using observations made by the Karl G. Jansky Very Large Array (VLA) at 1–2 GHz, Yu et al. reported a discovery of long-lasting auroral-like radio bursts persistent over a sunspot and interpreted them as ECM-generated emission. Here we investigate the detailed second and subsecond temporal variability of this continuous ECM source. We study the association of 5 s period QPPs with a concurrent GOES C1.5-class flare, utilizing VLA’s imaging spectroscopy capability with an extremely high temporal resolution (50 ms). We use the density and magnetic field extrapolation model to constrain the ECM emission to the second harmonic O-mode. Using the delay of QPPs from X-ray emission times, combined with X-ray spectroscopy and magnetic extrapolation, we constrain the energies and pitch angles of the ECM-emitting electrons to ≈4–8 keV and >26°. Our analysis shows that the loss-cone diffusion continuously fuels the ECM via Coulomb collisions and magnetic turbulence between a length scale of 5 and 100 Mm. We conclude that the QPP occurs via the Lotka–Volterra system, where the electrons from solar flares saturate the continuously operating ECM and cause temporary oscillations.