bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rapid postradiation malignant transformation of a pilocytic astrocytoma in an adult with neurofibromatosis type 1: illustrative case
Authors: Gupta Rohan V , Welch Jonathan C , Kaul Anand , Prayson Richard A , Rong Yuan , Almefty Rami O 
Published: August 2024

BACKGROUND
Juvenile pilocytic astrocytoma (JPA) is the most common primary brain tumor of childhood and is rarely seen in adults. Neurofibromatosis type 1 (NF1), a common tumor predisposition syndrome, demonstrates a strong association with low-grade gliomas, most notably pilocytic astrocytoma, which are relatively indolent. Unlike its juvenile counterpart, reports of adult pilocytic astrocytoma (APA) vary widely in terms of disease progression from benign to much more malignant courses. Moreover, current studies discussing APA report different treatment approaches and outcomes (e.g., malignant transformation of JPA and APA with or without radiation), as little is known regarding the management of recurrent tumors and how adjuvant therapies may alter disease progression.

OBSERVATIONS
The authors report the unique case of an adult male with NF1 and APA who underwent rapid malignant conversion after intensity-modulated radiation therapy.

LESSONS
The authors demonstrate that caution should be taken in utilizing radiotherapy instead of resection in cases of APA and NF1, with close monitoring for posttreatment recurrence.
https://thejns.org/doi/10.3171/CASE24241
IMPROVING STUDENTS’ LISTENING COMPREHENSION IN NARRATIVE TEXT BY USING DICTOGLOSS TECHNIQUE
Authors: Endriati Win , Sutapa Yuliana Yohanes Gatot , Bunau Eusabinus 
Published: August 2024

Abstract:The research was conducted based on the problems that were found in the teaching and learning process. The students faced some problems in listening to the narrative text: writing the right vocabulary based on the teacher's pronunciation, identifying important supporting details, and drawing inferences. The purpose of this research was to investigate how the Dictogloss technique improved students’ listening comprehension in listening narrative text on the eleventh grade students in class XI IPS 3 of SMAN 5 Pontianak in the academic year 2017/2018. The results showed that the implementation of the dictogloss technique in this research is successful in improving students’ listening comprehension in the narrative text, and the implementation of the dictogloss technique not only improves the students’ listening comprehension in the narrative text but also changes the students’ behavior in teaching and learning process and motivated them. To sum up, the research finding proved that the implementation of the dictogloss technique improved the students' listening comprehension in the narrative text to the eleventh grade students of SMAN 5 Pontianak in the academic year 2017/2018. Keywords: dictogloss technique, listening comprehension, narrative text.
Antimicrobial activities of essential oils of plants species from Morocco against some microbial strains
Authors: Bouftila Bouchra , Abdessadek Mohammed , Ben-Saghroune Hayat , Sbihi Karim , Ouahmane Loubna , Amri Oukacha , El Amraoui Belkassem 
Published: August 2024

BackgroundEssential oils have important antibacterial activities and can successfully replace antibiotics, which show their inefficiency, especially against fungi and multi-resistant bacteria.ObjectiveThe main purpose of our research was to investigate the antibacterial and antifungal activity of essential oils from fifteen plants harvested in the Taroudant region.Material and MethodsIn this work, the essential oils were extracted by hydrodistillation using a Clevenger-type apparatus. The method of disc diffusion in agar medium (aromatogram) is the one used to evaluate the activity of these essential oils against four pathogenic bacteria (Staphylococcus aureus, Escherichia coli, Bacillus sp., and Enterococcus cloacae) and two yeasts (Candida albicans and Cryptococcus neoformans).ResultsOur findings, show that all of the plants’ leaves yielded extremely aromatic essential oils that differed in look and color. Furthermore, the 93.33% of the fifteen essential oils that were evaluated proved to be effective against at least one kind of bacteria or fungus. This suggests that the proportion of essential oils with no antibacterial action was rather low, at around 7%. Our data also showed that the freshness or dryness of the plant at the time of harvest could affect the extraction rate of essential oils. This screening showed us that these essential oils present inhibitory activities towards the studied Gram+ bacteria, as well as a resistance against Gram-, in particular Enterococcus cloacae.ConclusionThese essential oils can therefore be used in the prevention and treatment of certain infectious diseases and to fight against bacteria that are multi-resistant to the usual antibiotics.
Digital Transformation: An Emphasis Analysis of Enterprise Resource Planning (ERP) Modules in Higher Education
Authors: Abdul Rezha Efrat Najaf  , Fitri Ana Wati Seftin , Saka Fitri Anindo 
Published: August 2024

Industry, and educational institutions in particular, regard digital transformation as a critical information technology. This is due to the fact that educational institutions are required to effectively respond to a multitude of changes, including those associated with digital transformation. This study aims to empirically analyze to the challenges associated with the process of digital transformation, this study examined pertinent scholarly publications, books, and journals. The utilization of the Enterprise Resource Planning (ERP) system in this research endeavors to assess ERP system modules that may be implemented in academic establishments to facilitate the digital transformation process while increasing the efficiency and effectiveness of information resource and technology management. In pursuit of global educational excellence and benchmarks. ERP modules implemented in educational institutions include Competency and Certificate Management, Career Service Management, Student Information Management, Financial and Accounting Management, Asset Management, and E-Learning Management. It is anticipated that the implementation of an ERP system in academic institutions will improve visibility, adaptability, and the capacity to strategize, plan, and operate more effectively. It is crucial to note, however, that many factors must be considered when implementing ERP system modules in academic institutions, including elevated costs, adequate resources, and stakeholder support.
THE USE OF FIGURATIVE LANGUAGE AND IMAGERY IN SONGS’ LYRICS
Authors: Tambunsaribu Gunawan , Sigalingging Bob Morison 
Published: August 2024

In literary works, most authors express their feelings by using figurative language in their writing. The languages used in literary works usually represent the explicit and implicit feelings and thoughts of their characters. Someone may use figurative language to create unique and aesthetic communication. This study aims to find out the use of figurative language and imagery found in the two songs from Bruno Mars’ album entitled "Talking to the Moon” and “It Will Rain”. This study uses a qualitative method with a descriptive approach. This research showed that figurative language and imagery found in Bruno Mars’ selected song lyrics represented the author’s feelings and expressions delivered indirectly. Based on research findings, the writer found some figurative language in Bruno Mars’ selected songs. The most figurative language used in the lyrics of Bruno Mars’ selected songs is “Hyperbole”. This is usually used to emphasize human expression. The writer used hyperbole to make the lyrics more interesting to the listeners. In conclusion, these two songs use many kinds of figurative language and imagery. In literature, a writer uses figurative language as a tool to express and emphasize the elements of feeling, emotion, and experiences of human beings. By using figurative language and imagery, the reader can understand and imagine the aim of the writer.
Multidisciplinary options for the correction of chronic nonspecific low back pain syndrome (literature review)
Authors: Sorokovikova T. V. , Menshikova T. V. , Morozov A. M. , Kryukova A. N. 
Published: August 2024

Chronic back pain is the complaint with which patients most often seek medical help from general practitioners, neurologists, surgeons, traumatologists and other subspecialists. Pain in the lower back can be either nonspecific, i. e., have no specific nosologic cause, or be specific, i. e., have a certain pathophysiologic mechanism of occurrence due to both spinal and extra-spinal causes. This fact determines the importance of complex and multidisciplinary assessment of the characteristics of chronic low back pain syndrome.The aim of the present study was to investigate the possibility of realizing a multidisciplinary approach in the treatment of nonspecific low back pain syndrome.Results. Low back pain is pain that is localized between the twelfth pair of ribs and the gluteal folds. It is not always possible to determine the source of pain when it is nonspecific; moreover, there is no convincing evidence that clarification of localization will favorably affect the course and outcome of the disease. There are three main causes of nonspecific low back pain: myofascial syndrome; pathology of joints and ligamentous apparatus of the spine; and lumbar osteochondrosis, which is a natural process of degeneration of spinal structures and is observed to varying degrees in all people, increasing significantly with age. It is believed that the pain syndrome of the back region has a multifaceted pathophysiology, which is influenced by somatic pathology, psychological and social factors. This explains the need for an integrated multidisciplinary approach to a particular patient and the compilation of an individual program of treatment, rehabilitation and prevention of subsequent exacerbations. Multidisciplinary approach means complex coordinated parallel work of specialists aimed at solving the problem of chronic pain.Conclusion. Multidisciplinary approach to the treatment of patients with chronic nonspecific low back pain syndrome is more effective than monotherapy, because it takes into account individual features of clinical symptoms, allows to carry out treatment and rehabilitation according to an individual plan, including a set of interrelated measures aimed at improving the quality of life of the patient and his functional capabilities.
The effectiveness of neurorehabilitation in inpatient department
Authors: Manysheva K. B. , Alieva B. B. , Emirgamzaev Sh. S. 
Published: August 2024

The objective of the study is to evaluate the effectiveness of rehabilitation treatment in patients with neurological pathology in inpatient department.Materials and methods. The study included 101 patients undergoing hospital treatment due to an existing neurological disease. The mean age was 52.41 ± 13.49 years. The condition of each patient upon admission and after the course of inpatient treatment was assessed using special tools – scales, tests, indices and questionnaires, such as the Rehabilitation Routing Scale and the modified Rankin scale, and according to the clinical specifics and needs of rehabilitation treatment – the Ashworth scale, Caprini Scale, Muscle Strength Grading Scale, National Institutes of Health Stroke Scale, HAS-BLED Scale, Berg Scale, Functional Independence Measure, Waterlow Score, Numeric Pain Rating Scale, Frenchay Arm Test, Rivermead Mobility Index, Hauser Index, EQ-5D, Barthel Index. The dynamics of recovery were calculated by comparing scores obtained using special instruments upon admission to rehabilitation treatment and after it.Results. By analyzing the results of the study, a positive dynamic of recovery was established, confirming the effectiveness of an inpatient course of neurorehabilitation, which is expressed in an improvement in the condition of patients when assessed using the designated tools for its objectification.Conclusions. The study confirms the effectiveness of an inpatient course of medical rehabilitation in restoring neurological deficits, increasing the activity of daily living, reducing the degree of social maladjustment and improving the rehabilitation prognosis.
Prognostic role of NT-proBNP and ultrasound assessment of venous congestion according to the VEXUS protocol in patients with acute decompensation of heart failure in the intensive care unit
Authors: Vatsik-Gorodetskaya M. V. , Petrikov S. S. , Tolkacheva V. V. , Kobalava Z. D. 
Published: August 2024

Aim. To determine the prognostic value of NT-proBNP and ultrasound assessment of venous congestion according to the VEXUS protocol in patients hospitalized with acute decompensation of heart failure (ADHF) in the intensive care unit (ICU) in relation to adverse outcomes for HF during a year of follow-up.Materials and methods. A prospective observational study included 150 patients hospitalized with ADHF in the ICU. All patients included in the study at admission and discharge underwent standard physical, laboratory and instrumental examinations, including NT-proBNP, lung ultrasound, assessment of venous congestion according to the VExUS protocol. The assessment of long-term clinical events was carried out by a structured telephone survey 1, 3, 6, 12 months after discharge. The total rate of total mortality and repeated hospitalizations for HF was estimated as the endpoint.Results. During 1 year of follow–up, 58 events (38 %) were detected, 50 deaths (33 %), 8 repeated hospitalizations (5 %). Patients with events were significantly older, characterized by more pronounced laboratory and instrumental assessment of congestion, diameter of the inferior vena cava, and venous congestion. The following threshold values were identified by ROC curves for predicting outcomes (total mortality + re–hospitalization) − the degree of venous congestion according to the VExUS GRADE protocol >2 and the level of NT-proBNP>10806 pg/ml at admission, the diameter of the inferior vena cava >2.3 cm at discharge.Conclusion: NT-proBNP>10806 pg/ml and GRADE>2 of venous congestion according to the VExUS protocol in patients admitted to the ICU with ADHF, have prognostic value in relation to the risk of adverse outcomes (total mortality and repeated hospitalizations) during a year of follow-up.
Effects of different adding methods of fermentation medium on the quality of cigar
Authors: Wen Cai , Shuanghong Yang , Wanrong Hu , Ran Chen , Zhishun Chai , Danqun Huo , Changjun Hou , Dongliang Li , Qianying Zhang 
Published: August 2024

Background: To investigate the effects of different media and media addition methods on the fermentation of tobacco.Methods: A plant extract and a bacterial agent are used for fermenting cigar tobacco leaves in a different order of addition. The chemical composition, cellulose, and pectin content, as well as changes in the microbial community, were measured.Results: The addition method of the fermentation medium affects the quality of fermented tobacco. The optimal medium formula and addition method involve first adding plant extracts and then microbial agents. The medium formula and addition method can significantly reduce cellulose in tobacco, with a reduction rate of 46%, and significantly increase the content of β-carotene, thereby enhancing the aroma of cigarettes. There is an increase in aroma components, such as alcohols, alkanes, and olefins, in tobacco. By reducing the proportion of Aspergillus, it can alter the microbial community structure of tobacco.Conclusion: Adding plant extracts before introducing microbial agents can significantly improve the quality and alter the microbial community structure of Dexue No.1 tobacco.
Feasibility of deescalating postoperative care in enhanced recovery after cardiac surgery
Authors: Stock Sina , Berger Veith Sarah , Holst Theresa , Erfani Sahab , Pochert Julia , Dumps Christian , Girdauskas Evaldas 
Published: August 2024

IntroductionEnhanced Recovery After Surgery (ERAS) prioritizes faster functional recovery after major surgery. An important aspect of postoperative ERAS is decreasing morbidity and immobility, which can result from prolonged critical care. Using current clinical data, our aim was to analyze whether a six-hour monitoring period after Minimally Invasive Cardiac Surgery (MICS) might be sufficient to recognize major postoperative complications in a future Fast Track pathway. Additionally, we sought to investigate whether it could be possible to deescalate the setting of postoperative monitoring.Methods358 patients received MICS and were deemed suitable for an ERAS protocol between 01/2021 and 03/2023 at our institution. Of these, 297 patients could be successfully extubated on-table, were transferred to IMC or ICU in stable condition and therefore served as study cohort. Outcomes of interest were incidence and timing of Major Adverse Cardiac Events (MACE; death, myocardial infarction requiring revascularization, stroke), bleeding requiring reexploration and Fast Track-associated complications (reintubation and readmission to ICU).ResultsPatients' median age was 63 years (IQR 55–70) and 65% were male. 189 (64%) patients received anterolateral mini-thoracotomy, primarily for mitral and/or tricuspid valve surgery (n = 177). 108 (36%) patients had partial upper sternotomy, primarily for aortic valve repair/replacement (n = 79) and aortic surgery (n = 17). 90% of patients were normotensive without need for vasopressors within 6 h postoperatively, 82% of patients were transferred to the general ward on postoperative day 1 (POD). Two (0.7%) MACE events occurred, as well as 4 (1.3%) postoperative bleeding events requiring reexploration. Of these complications, only one event occurred before transfer to the ward - all others took place on or after POD 1. There was one instance of reintubation and two of readmission to ICU.ConclusionsIf MICS patients can be successfully extubated on-table and are hemodynamically stable, major postoperative complications were rare in our single-center experience and primarily occurred after transfer to the ward. Therefore, in well selected MICS patients with uncomplicated intraoperative course, monitoring for six hours, possibly outside of an ICU, followed by transfer to the ward appears to be a feasible theoretical concept without negative impact on patient safety.
Minimally invasive vs. conventional mitral valve surgery: a meta-analysis of randomised controlled trials
Authors: Amin Aamir , Kumar Rajanikant , Mokhtassi Shiva Seyed , Alassiri Abdullah K. , Odaman Agatha , Khan Muhammad Ahmad Raza , Lakshmana Shashi , Din Zahir Ud , Acharya Pawan , Cheema Huzaifa Ahmad , Nashwan Abdulqadir J. , Khan Arsalan Ali , Hussain Awab , Bhudia Sunil , Vincent Royce P. 
Published: August 2024

ObjectiveThe evidence underlying the efficacy and safety of minimally invasive mitral valve surgery (MIMVS) is inconclusive. We conducted a meta-analysis to evaluate whether MIMVS improves clinical outcomes compared with conventional sternotomy.MethodsWe searched MEDLINE (via PubMed), Embase, the Cochrane Library, and ClinicalTrials.gov from inception to January 2024 for all randomised controlled trials (RCTs), comparing MIMVS with conventional mitral valve surgery. RevMan 5.4 was used to analyse the data with risk ratio (RR) and mean difference (MD) as the effect measures.ResultsEight studies reporting data on 7 RCTs were included in our review. There was no significant difference in all-cause mortality, the number of patients requiring blood product transfusion, and the change from baseline in the SF-36 physical function scores between the MIMVS and conventional sternotomy groups. MIMVS reduced the length of hospital stay (MD −2.02 days, 95% CI: −3.66, −0.39) but did not affect the length of ICU stay, re-operation for bleeding, and the incidence of renal injury, wound infection, neurological events, and postoperative moderate or severe mitral regurgitation. MIMVS was associated with a trend toward lower postoperative pain scores (MD −1.06; 95% CI: −3.96 to 0.75).ConclusionsMIMVS reduced the number of days spent in the hospital and showed a trend toward lower postoperative pain scores, but it did not decrease the risk of all-cause mortality or the number of patients needing blood product transfusions. Further large-scale RCTs are required to inform definitive conclusions, particularly with regard to quality-of-life outcomes investigating functional recovery.Systematic Review RegistrationPROSPERO (CRD42023482122).
Rejuvenating bone marrow hematopoietic reserve prevents regeneration failure and hepatic decompensation in animal model of cirrhosis
Authors: Nautiyal Nidhi , Maheshwari Deepanshu , Kumar Dhananjay , Rao E. Pranshu , Tripathi Dinesh Mani , Kumar Sandeep , Diwakar Sunidhi , Bhardwaj Manisha , Mohanty Sujata , Baligar Prakash , Kumari Anupama , Bihari Chhagan , Biswas Subhrajit , Sarin S. K. , Kumar Anupam 
Published: August 2024

Background and aimBone marrow stem cells (BM-SCs) and their progeny play a central role in tissue repair and regeneration. In patients with chronic liver failure, bone marrow (BM) reserve is severally compromised and they showed marked defects in the resolution of injury and infection, leading to liver failure and the onset of decompensation. Whether BM failure is the cause or consequence of liver failure during cirrhosis is not known. In this study, we aimed to determine the underlying relationship between BM failure and regeneration failure in cirrhosis.MethodologyC57Bl/6(J) mice were used to develop chronic liver injury through intra-peritoneal administration of carbon tetrachloride (CCl4) for 15 weeks (0.1-0.5 ml/kg). Animals were sacrificed to study the transition of cirrhosis and BM defects. To restore the BM-SC reserve; healthy BM cells were infused via intra-BM infusion and assessed for changes in liver injury, regeneration, and BM-SC reserve.ResultsUsing a CCl4-induced animal - model of cirrhosis, we showed the loss of BM-SCs reserve occurred before regeneration failure and the onset of non-acute decompensation. Intra-BM infusion of healthy BM cells induced the repopulation of native hematopoietic stem cells (HSCs) in cirrhotic BM. Restoring BM-HSCs reserve augments liver macrophage-mediated clearance of infection and inflammation dampens neutrophil-mediated inflammation, accelerates fibrosis regression, enhances hepatocyte proliferation, and delays the onset of non-acute decompensation.ConclusionThese findings suggest that loss of BM-HSCs reserve underlies the compromised innate immune function of the liver, drives regeneration failure, and the onset of non-acute decompensation. We further provide the proof-of-concept that rejuvenating BM-HSC reserve can serve as a potential therapeutic approach for preventing regeneration failure and transition to decompensated cirrhosis.