bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prophylactic antibodies inhibit spike‐specific T and B cell responses after COVID‐19 vaccination
Authors: Mei Henrik E. , Schulz Axel Ronald , Hirseland Heike , Diekmann Lisa‐Marie , Habermann Elisa , ten Hagen Alexander , Albach Fredrik , Burmester Gerd‐Rüdiger , Grützkau Andreas , Biesen Robert 
Published: July 2024

AbstractActive and passive immunization is used in high‐risk patients to prevent severe courses of COVID‐19, but the impact of prophylactic neutralizing antibodies on the immune reaction to the mRNA vaccines has remained enigmatic. Here we show that CD4 T and B cell responses to Spikevax booster immunization are suppressed by the therapeutic antibodies Casirivimab and Imdevimab. B cell and T cell responses were significantly induced in controls but not in antibody‐treated patients. The data indicates that humoral immunity, i. e. high levels of antibodies, negatively impacts reactive immunity, resulting in blunted cellular responses upon boosting. This argues for temporal separation of vaccination efforts; with active vaccination preferably applied before prophylactic therapeutic antibody treatment.
Transcriptional evidence for transient regulation of muscle regeneration by brown adipose transplant in the rotator cuff
Authors: Gui Chang , Meyer Gretchen 
Published: July 2024

AbstractChronic rotator cuff (RC) injuries can lead to a degenerative microenvironment that favors chronic inflammation, fibrosis, and fatty infiltration. Recovery of muscle structure and function will ultimately require a complex network of muscle resident cells, including satellite cells, fibro‐adipogenic progenitors (FAPs), and immune cells. Recent work suggests that signaling from adipose tissue and progenitors could modulate regeneration and recovery of function, particularly promyogenic signaling from brown or beige adipose (BAT). In this study, we sought to identify cellular targets of BAT signaling during muscle regeneration using a RC BAT transplantation mouse model. Cardiotoxin injured supraspinatus muscle had improved mass at 7 days postsurgery (dps) when transplanted with exogeneous BAT. Transcriptional analysis revealed transplanted BAT modulates FAP signaling early in regeneration likely via crosstalk with immune cells. However, this conferred no long‐term benefit as muscle mass and function were not improved at 28 dps. To eliminate the confounding effects of endogenous BAT, we transplanted BAT in the “BAT‐free” uncoupling protein‐1 diphtheria toxin fragment A (UCP1‐DTA) mouse and here found improved muscle contractile function, but not mass at 28 dps. Interestingly, the transplanted BAT increased fatty infiltration in all experimental groups, implying modulation of FAP adipogenesis during regeneration. Thus, we conclude that transplanted BAT modulates FAP signaling early in regeneration, but does not grant long‐term benefits.
A comparison of two models for detecting inconsistency in network meta‐analysis
Authors: Qin Lu , Zhao Shishun , Guo Wenlai , Tong Tiejun , Yang Ke 
Published: July 2024

AbstractThe application of network meta‐analysis is becoming increasingly widespread, and for a successful implementation, it requires that the direct comparison result and the indirect comparison result should be consistent. Because of this, a proper detection of inconsistency is often a key issue in network meta‐analysis as whether the results can be reliably used as a clinical guidance. Among the existing methods for detecting inconsistency, two commonly used models are the design‐by‐treatment interaction model and the side‐splitting models. While the original side‐splitting model was initially estimated using a Bayesian approach, in this context, we employ the frequentist approach. In this paper, we review these two types of models comprehensively as well as explore their relationship by treating the data structure of network meta‐analysis as missing data and parameterizing the potential complete data for each model. Through both analytical and numerical studies, we verify that the side‐splitting models are specific instances of the design‐by‐treatment interaction model, incorporating additional assumptions or under certain data structure. Moreover, the design‐by‐treatment interaction model exhibits robust performance across different data structures on inconsistency detection compared to the side‐splitting models. Finally, as a practical guidance for inconsistency detection, we recommend utilizing the design‐by‐treatment interaction model when there is a lack of information about the potential location of inconsistency. By contrast, the side‐splitting models can serve as a supplementary method especially when the number of studies in each design is small, enabling a comprehensive assessment of inconsistency from both global and local perspectives.
Understanding food safety challenges through a gender and social lens in low‐ and middle‐income countries
Authors: Milovanova Natalia , Chukwugozie Deborah C. , David Kezhiya , Okonji Blessing Anthonia , Njoagwuani Esther Ibe , Onwukaeme Ifeanyi Michael , Nnaji Nnabueze Darlington , Onyeaka Helen , Tamasiga Phemelo 
Published: July 2024

AbstractFood safety is crucial for ensuring the quality and safety of the global food supply. However, the gender and social dimensions of food safety are often overlooked and undervalued. Women, who are primary caretakers in households, play a vital role in food preparation, storage, and consumption. Gender inequality can result in limited access to resources and information needed for safe food handling and storage, increasing women's vulnerability to foodborne illnesses. Cultural practices, education, and income levels also impact food safety. These factors can contribute to disparities in food safety and increase the risk of foodborne illnesses among certain populations. Promoting gender equality, cultural sensitivity, and addressing income inequality are essential to ensure safe and secure food for all. Addressing these issues can lead to a more equitable and sustainable food system.
ReactionMechanismSimulator.jl: A modern approach to chemical kinetic mechanism simulation and analysis
Authors: Johnson Matthew S. , Pang Hao‐Wei , Payne Allen Mark , Green William H. 
Published: July 2024

AbstractWe present ReactionMechanismSimulator.jl (RMS), a modern differentiable software for the simulation and analysis of chemical kinetic mechanisms, including multiphase systems. RMS has already been applied to problems in combustion, pyrolysis, polymers, pharmaceuticals, catalysis, and electrocatalysis. RMS is written in Julia, making it easy to develop and allowing it to take advantage of Julia's extensive numerical computing ecosystem. In addition to its extensive library of optimized analytic Jacobians, RMS can generate and use Jacobians computed using automatic differentiation and symbolically generated analytic Jacobians. RMS is demonstrated to be faster than Cantera and Chemkin in several benchmarks. RMS also implements an extensive set of features for analyzing chemical mechanisms, including a library of easy‐to‐call plotting functions, molecular structure resolved flux diagram generation, crash analysis, traditional sensitivity analysis, transitory sensitivity analysis, and an automatic mechanism analysis toolkit. RMS implements efficient adjoint and parallel forward sensitivity analyses. We also demonstrate the ease of adding new features to RMS.
The Effect of Post‐Treatment Combined Lifestyle Interventions on Quality of Life in Colorectal Cancer Patients – A Systematic Review
Authors: Gielen Anke H. C. , Thomassen Britt J. M. , Bult Tim J. , Melenhorst Jarno , Kimman Merel L. , Breukink Stephanie O. 
Published: July 2024

ABSTRACTBackgroundColorectal cancer is identified as a lifestyle‐related type of cancer. There is an increasing emphasis on lifestyle interventions targeting pivotal lifestyle factors such as excess weight, cigarette smoking, alcohol consumption, poor diet and physical inactivity as primary and tertiary prevention. Furthermore, modifying these lifestyle factors has the potential to improve quality of life for cancer patients. We aim to identify, appraise and synthesise the available evidence regarding the effect of combined lifestyle interventions on quality of life in colorectal cancer survivors.MethodsPubmed, Ovid Embase and the Cochrane Library were searched for studies reporting on quality of life in post‐treatment colorectal cancer patients. The systematic literature search was performed according to the Preferred Reporting Items for systematic reviews and meta‐analysis (PRISMA) guidelines.ResultsFive articles reporting on 719 individual patients were included. Two studies reported significantly better results in (cancer‐specific) quality‐of‐life questionnaires for patients after combined lifestyle interventions.ConclusionWe conclude that there is some evidence that combined lifestyle interventions could have beneficial effects on the quality of life of colorectal cancer survivors. Future randomised controlled trials reporting on quality of life of combined lifestyle interventions in colorectal cancer survivors are warranted.
Carbon emissions from inland waters may be underestimated: Evidence from European river networks fragmented by drying
Authors: López‐Rojo Naiara , Datry Thibault , Peñas Francisco J. , Singer Gabriel , Lamouroux Nicolas , Barquín José , Rodeles Amaia A. , Silverthorn Teresa , Sarremejane Romain , del Campo Rubén , Estévez Edurne , Mimeau Louise , Boyer Frédéric , Künne Annika , Dalvai Ragnoli Martin , Foulquier Arnaud 
Published: July 2024

AbstractRiver networks contribute disproportionately to the global carbon cycle. However, global estimates of carbon emissions from inland waters are based on perennial rivers, even though more than half of the world's river length is prone to drying. We quantified CO2 and CH4 emissions from flowing water and dry riverbeds across six European drying river networks (DRNs, 120 reaches) and three seasons and identified drivers of emissions using local and regional variables. Drivers of emissions from flowing water differed between perennial and non‐perennial reaches, both CO2 and CH4 emissions were controlled partly by the annual drying severity, reflecting a drying legacy effect. Upscaled CO2 emissions for the six DRNs at the annual scale revealed that dry riverbeds contributed up to 77% of the annual emissions, calling for an urgent need to include non‐perennial rivers in global estimates of greenhouse gas emissions.
Monitoring tides, currents, and waves along coastal habitats using the Mini Buoy
Authors: Ladd Cai J. T. , Vovides Alejandra G. , Wimmler Marie‐Christin , Schwarz Christian , Balke Thorsten 
Published: July 2024

AbstractIntertidal habitats are shaped by the actions of tides and waves which are difficult to monitor in shallow water. To address this challenge, the “Mini Buoy” and associated open‐source App were recently developed for the low‐cost and long‐term monitoring of tidal inundation and current velocities simultaneously. The Mini Buoy is a bottom‐mounted float that measures tilt to infer near‐bed hydrodynamics. Here, we present significant updates to the Mini Buoy and App. Two new Mini Buoy designs were calibrated: the “Pendant” that requires minimal assembly for deployment, and the “B4+” that can also measure wave orbital velocity. Comparisons against industry‐standard water‐level and velocity sensors deployed in the field showed that each new design was effective at detecting tidal inundation (overall accuracy of 86–97%) and current velocities (R2 = 0.73–0.91; accuracies of ± 0.14–0.22 m s−1; detection limits between 0.02 and 0.8 m s−1). The B4+ could reasonably measure wave orbital velocities (R2 = 0.56; accuracies of ± 0.18 m s−1; detection limits between 0.02 and 0.8 m s−1). Reducing the sampling rate to prolong survey durations did not markedly reduce the precision of velocity measurements, except in the original Mini Buoy design (uncertainty increased by ± 2.11 m s−1 from 1 to 10 s sampling). The updated App enhances user experience, accepts data from any Mini Buoy design, is suitable for generic use across any tidal setting, and presents multiple options to understand and contrast local hydrodynamic regimes. Improvements to the Mini Buoy designs and App offer greater opportunities in monitoring hydrodynamics for purposes including ecosystem restoration and flood risk management.
Using a baited imaging sonar (BISON) to quantify the density, size, and detection range of fishes in a shallow, nearshore habitat
Authors: Sibley Edward C. P. , Boswell Kevin M. , Binder Benjamin M. , White Allison L. , Mell Aedan M. , Scott Beth E. , Madgett Alethea S. , Elsdon Travis S. , Marnane Michael J. , Fernandes Paul G. 
Published: July 2024

AbstractMethods that supplement optical instruments with bait, such as baited remote underwater video (BRUV), are used worldwide to detect and quantify marine life. Optical instruments only detect targets within visible range, such that BRUVs may underestimate fishes in light‐limited habitats, especially fishes that respond to the bait at ranges beyond visibility. Alternatively, light‐independent instruments (e.g., imaging sonars) can detect and quantify fishes regardless of visibility. This study presents the first application of a baited imaging sonar (BISON), deployed to survey fishes around a small, shallow artificial habitat in a turbid embayment in southern Florida. To establish the influence of bait on fish detection, BISON trials were alternately conducted alongside deployments of an unbaited control, with a high‐definition camera integrated to ascertain visibility and inform species composition. For fishes of two size classes, larger (> 30 cm) and smaller (10–30 cm), maximum density (MaxD) and range of detection were quantified. Although the densities of larger and smaller fishes quantified by the BISON and unbaited control did not differ, over 55% of larger fishes were detected at ranges beyond maximum visibility, with asymptotes in fish density on the BISON identified at 15–20 min and 5–10 min for larger and smaller fishes, respectively. Overall, this study demonstrates the potential of BISONs as both a complementary and alternative method to BRUVs for quantifying fishes, especially in habitats of limited visibility. Future applications of BISONs in other habitats will further demonstrate its value as a tool to detect and enumerate aquatic assemblages.
High‐Resolution Integral Imaging Display Using Targeted Optimized Compound Lens Array for Voxel Aliasing Elimination
Authors: Liu Yi‐Jian , Wen Xue‐Rui , Hu Xiao‐Shuai , Li Wei‐Ze , Xing Yan , Liu Chao , Zhang Han‐Le , Wang Qiong‐Hua 
Published: July 2024

AbstractIntegral imaging (InIm) 3D displays provide realistic 3D images with comfortable viewing experiences. However, existing approaches struggle to achieve high spatial resolution reproduction without relying on temporal or spatial multiplexing methods, which increases system complexity. Although precise control approaches for voxel formation have been explored to address this challenge, the existing methods lack systematic analysis theories for identifying the key factors affecting spatial resolution. In this study, a novel analysis framework is proposed that uses a point spread function (PSF) to characterize voxel formation. An analytical model based on the obtained PSF is established to achieve an aliasing‐free display. This framework identifies optimization directions for improving the spatial resolution, specifically by reducing the Gaussian blur caused by wavefront aberration in the lens unit. A targeted optimization of a compound lens array is conducted to achieve precise control of voxel formation. In these experiments, an InIm 3D display system prototype that substantially outperforms conventional InIm 3D displays is developed. The prototype achieves a 74.6% reduction in the system PSF and a 29.85% reduction in voxel size, enabling aliasing‐free voxels and a 2.82 times higher resolution in the InIm 3D display.
Optimizing Energy Transfer: Suppressing Cs2ZnCl4 Self‐Trapped States and Boosting Ce3+ Ion Luminescence Efficiency
Authors: Wen Ziying , Bai Yunfei , Meng Qichao , Zhao Hongyuan , Wang Qiujie , Sun Haibo , Huang Li , Huang Dan , Yu William W. , Zhu Jun , Liu Feng 
Published: July 2024

AbstractIncorporating trivalent cerium ions (Ce3+) into colloidal semiconductor nanomaterials, such as zinc sulfide (ZnS) and cesium lead chloride (CsPbCl3), provides a feasible approach for achieving significant Ce3+ photoluminescence (PL). However, due to inefficient intersystem crossing and intense non‐radiative decay of host phosphors, most Ce3+‐doped luminophores exhibit low luminescence efficiency, with photoluminescence quantum yield (PLQY) typically <50%. Additionally, these doping systems often encounter challenges with spectral impurity due to unwanted fluorescence emanating from the host material. In this study, an optimal cesium zinc chloride (Cs2ZnCl4) nanorod (NR) host matrix is meticulously engineered, that significantly enhances the luminescence of Ce3+ ions, reaching a PLQY near unity. Furthermore, these NRs display an exceptionally pure Ce3+ emission spectrum, free from any extraneous emission from the matrix itself. The results from transient absorption and emission experiments reveal a ≈100% energy transfer efficiency from Cs2ZnCl4 to Ce3+, coupled with a significant reduction in radiative self‐trapped states within the host.
Channel selection strategy with consumer impulse purchase in livestream selling
Authors: Chen Lidong , Xu Qingyun , He Yi 
Published: July 2024

AbstractConsumer impulsive purchasing is very common, especially in the livestream selling where they are influenced by policies such as low prices, limited time, and limited quantity. This behavior can increase a firm's sales, but it also leads to higher return rates. Considering consumer impulse purchase, this paper conducts an analytical model to investigate the conditions for a firm to introduce a livestream channel and whether the firm should adopt a low or moderate livestream price strategy when introducing a livestream channel. Our results show that, when return processing cost is small enough, the firm benefits from the livestream strategies as long as the streamer's fan effect is larger than a threshold. Specifically, a firm prefers to adopt the low livestream price strategy when cooperating with a large fan effect streamer and a moderate livestream price strategy with a small fan effect streamer. However, when return processing cost is large, the low livestream price strategy cannot be the dominant strategy. Furthermore, we make several extensions (i.e., different impulse utility on different livestream price, impact of positive impulse utility of low impulsive consumers, different online return rates of different types of consumers, the costs of introducing the livestream channel, and consumer return processing cost) to verify the robustness of the model, and the main conclusions remain unchanged. These results provide guidance for firms on the introduction of livestream channel and pricing decisions of different channels.
An exploration of omni‐channel retail from a three‐party evolutionary game perspective: Brand strength vs. platform stream
Authors: Zhao Chuan , Guo Ziyang , He Mingke , Wang Kun 
Published: July 2024

AbstractThis study builds a three‐party evolutionary game to study the contributing factors of commission rate, productivity expansion, cooperation subsidy, brand strength, and platform stream. The proposed model investigates the diverse paths the three parties are motivated to pursue at different phases of omni‐channel integration and further explores which party, the band owner with strong brand strength, or the platform with a mass consumer stream, dominates omni‐channel negotiation regarding profit distribution arrangements.
Bridging digital and knowledge divides: Concepts, frameworks and ethical concerns
Authors: Kuiler Erik W. 
Published: July 2024

AbstractSince time immemorial, the hegemonic imposition of cultural and political power asymmetries has resulted in the de jure and de facto exclusion of certain groups from the common weal. Withe the introduction of digital information and communication technologies (ICT), the rifts between the ‘haves’ and the ‘have‐nots’ have expanded at nearly exponential rates. To provide an instrument for analysing the complexities of bridging the digital and knowledge divides, a conceptual framework is presented that provides different perspectives on agency in the commonwealth and the infosphere, which, in turn, leads to a discussion of the operationalization of ethics and justice in human rights that directly affect the entelechy of wellbeing. This discussion provides a basis for exploring certain aspects of social‐cultural barriers to wellbeing, the commodification of human rights, digital imperialism and cultural hegemonies in the world polity, including the infosphere, that have a direct bearing on the wellbeing of all in the common weal. A summary and a call‐to‐action complete the study.
Vivo application of a portable plasma generator in infected wound healing
Authors: Dang Mingze , Li Yiqian , Nie Lanlan , Zhao Feng , Jin Shaohui , Chen Xi , Lu Xinpei , Gan Lu 
Published: July 2024

AbstractIn this study, a portable plasma generator produced large‐area air plasma for treating infected wounds in BALB/c mice. Different plasma treatment times (30 s, 1 min, 3 min, and 4.5 min) were applied daily until the wounds healed completely. Results showed reduced inflammation and increased vascular endothelial growth factor (VEGF) expression in tissues treated for 1 and 3 min, promoting blood vessel proliferation and collagen fiber synthesis. However, treatment for 30 s and 4.5 min worsened inflammation and decreased VEGF expression. Overall, a 1‐min treatment was the most effective in promoting wound healing. Cold plasma shows promise for healing infected wounds, with treatment duration being a crucial factor.
Study of a full coaxial atmospheric pressure plasma jet device and its application to the modification of polytetrafluoroethylene
Authors: Zhang Dai , Xu Shuchang , Hou Zhenguo , Chang Xijiang , Wu Zhonghang , Xiong Zilan 
Published: July 2024

AbstractIn this article, a compact and portable microwave atmospheric pressure plasma jet (MW‐APPJ) generator based on a coaxial transmission line resonator (CTLR) was proposed. Based on the electromagnetic simulations, the jet generator was designed as a tapered inner conductor structure that ensures plasma generation at low power. A self‐igniting argon (Ar) plasma jet of 10 mm length was generated at an input power of ~20 W and maintained at 2 W. Thanks to the high efficiency of the CTLR structure, plasmas of mixed reactive gases were also realized. Intrinsic plasma parameters and active species were determined using optical emission spectroscopy. Furthermore, the MW‐APPJ device was used to modify the polytetrafluoroethylene surface, and improvement of hydrophilicity was achieved without thermal damage.
Selective productions of reactive species in dielectric barrier discharge by controlling dual duty cycle
Authors: Lim Jun S. , Admasu Kirubel A. , Choi Eun H. 
Published: July 2024

AbstractThis study analyzes the selective productions of nitrogen oxides and ozone in dielectric barrier discharge due to temperature controlled by the dual duty cycle. In this work, we varied the dual duty cycle of the output voltage in the power supply, which alternatively generates distinguished high and low‐temperature modes for selective productions of nitrogen oxides and ozone. The alternating nitric oxide and ozone by dual duty cycle were measured at a maximum of 100 ppm and 100 ppm in the gas phase, respectively. In the evaluation of DI water treated by dual duty cycle, nitrogen oxides, and ozone have been observed simultaneously in the liquid phase. These results offer new insights into the selective production of temperature‐dependent chemical characteristics for advanced plasma applications.