bluuebunny/crossref_metadata_2025_split huggingface dataset:
Postsynthetische “Photoklick”‐Modifizierung von DNA
Authors: Arndt Stefanie , Wagenknecht Hans‐Achim 
Published: October 2014

AbstractEin neu synthetisierter DNA‐Baustein auf Basis von 2′‐Desoxyuridin trägt in der 5‐Position ein über eine Aminopropinylgruppe verknüpftes, push‐pull‐substituiertes Diaryltetrazol. Das damit modifizierte Oligonucleotid ermöglicht die postsynthetische Markierung mit einem Maleinimid tragenden Sulfo‐Cy3‐Farbstoff, N‐Methylmaleinimid und Methylmethacrylat als Dipolarophile jeweils durch Bestrahlung mit Licht bei λexc=365 nm (LED). Die experimentell bestimmte Geschwindigkeitskonstante beträgt (23±7) M−1 s−1 und ist bemerkenswert groß gegenüber denen anderer kupferfreier, bioorthogonaler Reaktionen und ähnlich groß wie jene der kupferkatalysierten Cycloaddition von Aziden mit Acetylenen.
Transparent Metal Selenide Alloy Counter Electrodes for High‐Efficiency Bifacial Dye‐Sensitized Solar Cells
Authors: Duan Yanyan , Tang Qunwei , Liu Juan , He Benlin , Yu Liangmin 
Published: October 2014

AbstractThe exploration of cost‐effective and transparent counter electrodes (CEs) is a persistent objective in the development of bifacial dye‐sensitized solar cells (DSSCs). Transparent counter electrodes based on binary‐alloy metal selenides (M‐Se; M=Co, Ni, Cu, Fe, Ru) are now obtained by a mild, solution‐based method and employed in efficient bifacial DSSCs. Owing to superior charge‐transfer ability for the I−/I3− redox couple, electrocatalytic activity toward I3− reduction, and optical transparency, the bifacial DSSCs with CEs consisting of a metal selenide alloy yield front and rear efficiencies of 8.30 % and 4.63 % for Co0.85Se, 7.85 % and 4.37 % for Ni0.85Se, 6.43 % and 4.24 % for Cu0.50Se, 7.64 % and 5.05 % for FeSe, and 9.22 % and 5.90 % for Ru0.33Se in comparison with 6.18 % and 3.56 % for a cell with an electrode based on pristine platinum, respectively. Moreover, fast activity onset, high multiple start/stop capability, and relatively good stability demonstrate that these new electrodes should find applications in solar panels.
Total Syntheses of (−)‐Huperzine Q and (+)‐Lycopladines B and C
Authors: Hong Benke , Li Houhua , Wu Jinbao , Zhang Jing , Lei Xiaoguang 
Published: October 2014

AbstractUtilizing a late‐stage enamine bromofunctionalization strategy, the twelve‐step total synthesis of (−)‐huperzine Q was accomplished. Furthermore, the first total syntheses of (+)‐lycopladines B and C are described. An unprecedented X‐ray crystal structure of an unusual epoxyamine intermediate is also reported, and the synthetic application of this intermediate in natural product synthesis is demonstrated.
Adaptive Nonlinear Control of Wind Energy Conversion System Involving Induction Generator
Authors: Lajouad Rachid , Magri Abdelmounime El , Fadili Abderrahim El , Chaoui Fatima‐Zahra , Giri Fouad 
Published: October 2014

AbstractThis paper presents a theoretical framework for adaptive control of a wind energy conversion system (WECS), involving a squirrel cage induction generator (SIG) connected with an AC/DC/AC IGBT‐based PWM converter. A multi‐loop nonlinear controller is designed to meet two main control objectives, i.e., (i) speed reference optimization in order to extract a maximum wind energy whatever the wind speed, and (ii) power factor correction (PFC) to avoid net harmonic pollution. These objectives must be achieved despite the mechanical parameters uncertainty. First, a nonlinear model of the whole controlled system is developed within the Park coordinates. Then, a multi‐loop nonlinear controller is synthesized using the adaptive backstepping design. A formal analysis based on Lyapunov stability is carried out to describe the control system performances. In addition to closed‐loop global asymptotic stability, it is proven that all control objectives (induction generator speed tracking, rotor flux regulation, DC link voltage regulation and unitary power factor) are asymptotically achieved.
Branched‐chain amino acids supplementation protects streptozotocin‐induced insulin secretion and the correlated mechanism
Authors: Lu Ming , Zhang Xiujuan , Zheng Dongmei , Jiang Xiuyun , Chen Qing 
Published: October 2014

AbstractSignificant evidence demonstrates that oxidative stress can impair insulin secretion and contribute to the development of type 2 diabetes. Branched‐chain amino acids (BCAAs) are reported to be positively related to insulin secretion. This study aimed to determine how oxidative stress affects the function of islets and whether BCAAs can ameliorate the oxidative stress, and accompanying c‐jun N‐terminal kinase (JNK), protein kinase D1 (PKD1), and pancreatic/duodenal homeobox‐1 (PDX‐1) changes induced by streptozotocin (STZ). Plasma glucose, plasma insulin, and JNK, PKD1 and PDX‐1 mRNA and protein expression were measured in rats treated with STZ and BCAAs. The glucose level in STZ‐induced diabetic rats was much higher than that in control animals, and the elevated plasma glucose level in diabetic rats could be significantly inhibited by BCAAs treatment. Consistent with the change in glucose levels, the levels of insulin were also affected by BCAAs treatment. The mRNA and protein expression of JNK, PDX‐1, and PKD1 were significantly altered in diabetic rats compared with the control group (P < 0.01) and treatment with a low dose of BCAA reversed these changes in those above markers significantly (P < 0.01). The present study demonstrated that STZ‐induced oxidative stress could reduce serum insulin levels and alter the JNK, PDX‐1, and PKD1 expression. BCAAs restored the levels of serum insulin reversed changes in JNK, PDX‐1, and PKD1 expression. © 2014 BioFactors, 41(2):127–133, 2015.
High frequency of lobular breast cancer in distant metastases to the orbit
Authors: Raap Mieke , Antonopoulos Wiebke , Dämmrich Maximilian , Christgen Henriette , Steinmann Diana , Länger Florian , Lehmann Ulrich , Kreipe Hans , Christgen Matthias 
Published: October 2014

AbstractMetastasis to the periocular soft tissue of the orbit is a rare manifestation of metastatic cancer. Infiltrating lobular breast cancer (ILBC) is a special breast cancer subtype, which accounts for 10–15% of all mammary carcinomas and for ~1% of all malignancies. Here, we report on a high frequency of lobular breast cancer in patients with orbital metastases identified in an original series of metastatic tumor specimens and by a systematic literature review. A series of 14 orbital metastases was compiled from formalin‐fixed paraffin‐embedded archival tissues. All cases were subjected to histological re‐review and detailed immunophenotypical characterization. In addition, we performed a meta‐analysis of 68 previously published case reports describing orbital metastases, with special reference to breast cancer subtypes. Based on clinical history, histomorphology, immunophenotype, and/or comparison with matched primary tumors, orbital metastases were derived from breast cancer in 8/14 cases, seven of which were classified as metastatic lobular breast cancer. Other entities included non‐small cell lung cancer (4/14), infiltrating ductal breast cancer (1/14), prostate cancer (1/14) and adenocarcinoma of the esophagus (1/14). In line with this original series of orbital metastases, lobular breast cancer was the most common malignancy in 72 patients with orbital metastases described in 68 independent case reports. In conclusion, lobular breast cancer represents the cancer subtype with the highest prevalence among orbital metastases. The high frequency of ILBC in orbital metastases illustrates the special metastatic behavior of this tumor entity and may have implications for the understanding of the organotropism of metastatic lobular breast cancer.
Discrimination of p53 immunohistochemistry‐positive tumors by its staining pattern in gastric cancer
Authors: Ando Koji , Oki Eiji , Saeki Hiroshi , Yan Zhao , Tsuda Yasuo , Hidaka Gen , Kasagi Yuta , Otsu Hajime , Kawano Hiroyuki , Kitao Hiroyuki , Morita Masaru , Maehara Yoshihiko 
Published: October 2014

AbstractImmunohistochemistry staining of p53 is a cheap and simple method to detect aberrant function of p53. However, there are some discrepancies between the result of immunohistochemistry staining and mutation analysis. This study attempted to find a new definition of p53 staining by its staining pattern. Immunohistochemistry staining of p53 and TP53 gene mutation analysis were performed in 148 gastric cancer patients. Also SNP‐CGH array analysis was conducted to four cases. Positive staining of p53 was observed in 88 (59.5%) tumors. Tumors with positive p53 staining showed malignant features compared to negative tumors. Mutation of TP53 gene was observed in 29 (19.6%) tumors with higher age and differentiated type. In positive p53 tumors, two types could be distinguished; aberrant type and scattered type. With comparison to TP53 gene mutation analysis, all the scattered type had wild‐type TP53 gene (P = 0.0003). SNP‐CGH array showed that scattered‐type tumors had no change in the structure of chromosome 17. P53‐scattered‐type staining tumors may reflect a functionally active nonmutated TP53 gene. In interpretation of p53 immunohistochemistry staining, distinguishing p53‐positive tumors by their staining pattern may be important in gastric cancer.
Single‐Crystal‐like Nanoporous Spinel Oxides: A Strategy for Synthesis of Nanoporous Metal Oxides Utilizing Metal‐Cyanide Hybrid Coordination Polymers
Authors: Zakaria Mohamed B. , Hu Ming , Imura Masataka , Salunkhe Rahul R. , Umezawa Naoto , Hamoudi Hicham , Belik Alexei A. , Yamauchi Yusuke 
Published: October 2014

AbstractDevelopment of a new method to synthesize nanoporous metal oxides with highly crystallized frameworks is of great interest because of their wide use in practical applications. Here we demonstrate a thermal decomposition of metal‐cyanide hybrid coordination polymers (CPs) to prepare nanoporous metal oxides. During the thermal treatment, the organic units (carbon and nitrogen) are completely removed, and only metal contents are retained to prepare nanoporous metal oxides. The original nanocube shapes are well‐retained even after the thermal treatment. When both Fe and Co atoms are contained in the precursors, nanoporous FeCo oxide with a highly oriented crystalline framework is obtained. On the other hand, when nanoporous Co oxide and Fe oxide are obtained from Co‐ and Fe‐contacting precursors, their frameworks are amorphous and/or poorly crystallized. Single‐crystal‐like nanoporous FeCo oxide shows a stable magnetic property at room temperature compared to poly‐crystalline metal oxides. We further extend this concept to prepare nanoporous metal oxides with hollow interiors. Core‐shell heterostructures consisting of different metal‐cyanide hybrid CPs are prepared first. Then the cores are dissolved by chemical etching using a hydrochloric acid solution (i.e., the cores are used as sacrificial templates), leading to the formation of hollow interiors in the nanocubes. These hollow nanocubes are also successfully converted to nanoporous metal oxides with hollow interiors by thermal treatment. The present approach is entirely different from the surfactant‐templating approaches that traditionally have been utilized for the preparation of mesoporous metal oxides. We believe the present work proves a new way to synthesize nanoporous metal oxides with controlled crystalline frameworks and architectures.
The First Boroselenates as new Silicate Analogues
Authors: Daub Michael , Hillebrecht Harald 
Published: October 2014

AbstractThe first boroselenates were obtained as single crystals by the reaction of selenic acid with boron acid and the corresponding alkali carbonates. The structure determinations showed a far‐reaching analogy to very recently described borosulfates and the borophosphates, that is, tetrahedral BO4 and SeO4 units linked by common corners. In each case, the BO4 tetrahedra are surrounded by SeO4 tetrahedra. As a function of the B/Se ratio, this results in chains (1:3; Cs3[B(SeO4)3], Rb3[B(SeO4)3]), isolated pentamers (1:4; HK4[(B(SeO4)4]), or pentamers with additional isolated SeO4 tetrahedra (1:5; (H3O)Na6[B(SeO4)4](SeO4). Compound Rb3[B(SeO4)3] (orthorhombic, Ibca, Z=8, a=7.508(2), b=15.249(3), c=23.454(5) Å) is isotypic to Rb3[B(SO4)3]) and Ba3[B(PO4)3]. Compound Cs3[B(SeO4)3] (monoclinic, P21/c, Z=4, a=11.3552(4), b=7.9893(3), c=15.7692(6) Å, β=101.013(1)°) represents a distorted variant of Rb3[B(SeO4)3]. The isolated pentamers in HK4[(B(SeO4)4]) (triclinic, P$\bar 1$, Z=6, a=7.5303(1), b=7.5380(1), c=42.3659(4) Å, α=88.740(1), β=89.971(1), γ=89.971(1)°) were also found in K5[(B(SO4)4] and Na5[(B(SO4)4]. Compound (H3O)Na6[B(SeO4)4](SeO4) (tetragonal, I$\bar 4$, a=9.9796(1), c=18.2614(2) Å) is a super structure of the borophosphates Sr6[B(PO4)4](PO4) and Pb6[B(PO4)4](PO4). Because the tetrahedra are only connected through apices, there are topological analogies to silicates. Therefore, boroselenates may have a similar variability of crystal structures, such as borosulfates and borophosphates.
Chiral Ligands Derived from Monoterpenes: Application in the Synthesis of Optically Pure Secondary Alcohols via Asymmetric Catalysis
Authors: El Alami Mohammed Samir Ibn , El Amrani Mohamed Amin , Agbossou‐Niedercorn Francine , Suisse Isabelle , Mortreux André 
Published: October 2014

AbstractThe preparation of optically pure secondary alcohols in the presence of catalysts based on chiral ligands derived from monoterpenes, such as pinenes, limonenes and carenes, is reviewed. A wide variety of these ligands has been synthesized and used in several catalytic reactions, including hydrogen transfer, CC bond formation via addition of organozinc compounds to aldehydes, hydrosilylation, and oxazaborolidine reduction, leading to high activities and enantioselectivities.
Competing Pathways in the Photogeneration of Didehydrotoluenes from (Trimethylsilylmethyl)aryl Sulfonates and Phosphates
Authors: Crespi Stefano , Ravelli Davide , Protti Stefano , Albini Angelo , Fagnoni Maurizio 
Published: October 2014

AbstractThe scope of the photochemical generation of α,n‐didehydrotoluene diradicals from aryl sulfonates and phosphates and their chemistry are explored. The thermally inaccessible α,2‐ and α,4‐ intermediates are efficiently obtained by irradiation of ortho‐ and para‐(trimethylsilylmethyl)phenyl triflates through heterolytic splitting of the ester anion from the substrate in the triplet state. Triplet phenyl cations are formed and the loss of trimethylsilyl cation from them affords the desired diradicals (3Me3SiCH2C6H4‐OZ→3Me3SiCH2C6H4+→⋅CH2C6H4⋅). Triplet sensitization is required, for which acetone is used throughout. Direct irradiation leads, on the contrary, to photo‐Fries fragmentation (1Me3SiCH2C6H4O‐Z→Me3SiCH2C6H4O⋅+Z⋅). With mesylates, where ester cleavage is less convenient, a further competition from the triplet is direct desilylation. Didehydrotoluenes are also obtained from the corresponding phosphates, although with poor efficiency.
Rhodium(III)‐ and Iridium(III)‐Catalyzed C7 Alkylation of Indolines with Diazo Compounds
Authors: Ai Wen , Yang Xueyan , Wu Yunxiang , Wang Xuan , Li Yuanchao , Yang Yaxi , Zhou Bing 
Published: October 2014

AbstractA RhIII‐catalyzed procedure for the C7‐selective CH alkylation of various indolines with α‐diazo compounds at room temperature is reported. The advantages of this process are: 1) simple, mild, and pH‐neutral reaction conditions, 2) broad substrate scope, 3) complete regioselectivity, 4) no need for an external oxidant, and 5) N2 as the sole byproduct. Furthermore, alkylation and bis‐alkylation of carbazoles at the C1 and C8 positions have also been developed. More significantly, for the first time, a successful IrIII‐catalyzed intermolecular insertion of arene CH bonds into α‐diazo compounds is reported.
ChemInform Abstract: Luminescent Properties of SrZn2(PO4)2:Tb3+ and Its Luminescence Improvement by Incorporating A+ (A: Li, Na, and K).
Authors: Li Panlai , Wang Zhijun , Yang Zhiping , Guo Qinglin 
Published: October 2014

AbstractThe new title phosphor is synthesized by solid state reaction of SrCO3, ZnO, NH4H2PO4, and Tb4O7 (corundum crucibles, 900 °C, 5 h).
ChemInform Abstract: Surfactant‐Thermal Method to Prepare Two Novel Two‐Dimensional Mn—Sb—S Compounds for Photocatalytic Applications.
Authors: Nie Lina , Xiong Wei‐Wei , Li Peizhou , Han Jianyu , Zhang Guodong , Yin Shengming , Zhao Yanli , Xu Rong , Zhang Qichun 
Published: October 2014

AbstractThe new two‐dimensional compounds (IV) and (VII) crystallize in the monoclinic space group C2/c with Z = 4 (single crystal XRD).
ChemInform Abstract: Pr1.33Pt4Ga10: Superstructure and Magnetism.
Authors: Doan Nguyen Sau , Ryan Kevin , Chai Ping , Shatruk Michael , Xin Yan , Chapman Karena W. , Chupas Peter J. , Fronczek Frank R. , Macaluso Robin T. 
Published: October 2014

AbstractPr1.33Pt4Ga10 single crystals are prepared from the elements using excess Ga as flux (alumina crucible in evacuated silica ampoule, 1150 °C, 4 h, 2; ≈10% yield).
ChemInform Abstract: Formal anti‐Markovnikov Hydroamination of Terminal Aryl Alkynes with Pinacolborane and Hydroxylamines via Zr/Cu Sequential Catalysis.
Authors: Sakae Ryosuke , Hirano Koji , Satoh Tetsuya , Miura Masahiro 
Published: October 2014

AbstractPerforming the reaction with aliphatic terminal alkynes such as 1‐hexyne is unsuccessful.
ChemInform Abstract: Catalytic Hydrogenation of Amino Acids to Amino Alcohols with Complete Retention of Configuration
Authors: Tamura Masazumi , Tamura Riku , Takeda Yasuyuki , Nakagawa Yoshinao , Tomishige Keiichi 
Published: October 2014

Abstractusing a rhodium/molybdenum mixed oxide on silica as effective heterogeneous catalyst
ChemInform Abstract: A Rapid and Convenient Synthesis of gem‐Bis(dithiocarbamate) Derivatives from Primary Aliphatic Amines, Carbon Disulfide, and Aromatic Aldehydes Using Boron Trifluoride‐Diethyl Etherate.
Authors: Nemati Firouzeh , Gharjeh Ghiyaei Ali Ghorbani , Notash Behrouz , Shayegan Mojtaba Hajiloo , Amani Vahid 
Published: October 2014

AbstractThe title synthesis is advantageous with regards to high yields, mild reaction conditions and good functional group tolerance.
ChemInform Abstract: A Highly Active and Easily Recoverable Chitosan@Copper Catalyst for the C—S Coupling and Its Application in the Synthesis of Zolimidine.
Authors: Shen Chao , Xu Jun , Yu Wenbo , Zhang Pengfei 
Published: October 2014

AbstractThe newly prepared chitosan/Cu system catalyzes the coupling of aryl iodides (I) with sodium sulfinates (II) to give sulfones (III) (25 examples) in good to excellent yields.
ChemInform Abstract: Functionalized BINOL‐mono‐PHOS for Multinuclear Cu‐Catalysts in Asymmetric Conjugate Addition of Organozinc Reagents.
Authors: Endo Kohei , Yakeishi Sayuri , Hamada Daisuke , Shibata Takanori 
Published: October 2014

AbstractThe syntheses of ligands (I) as well as derivatives thereof are described.
ChemInform Abstract: Use of 2‐Bromophenylboronic Esters as Benzyne Precursors in the Pd‐Catalyzed Synthesis of Triphenylenes.
Authors: Garcia‐Lopez Jose‐Antonio , Greaney Michael F. 
Published: October 2014

Abstractortho‐Bromo substituted arylboronic pinacolates are introduced as novel aryne precusors allowing an efficient preparation of triphenylene derivatives.
ChemInform Abstract: Asymmetric Synthesis of Spiropyrazolones Through Phosphine‐Catalyzed [4 + 1] Annulation.
Authors: Han Xiaoyu , Yao Weijun , Wang Tianli , Tan Yong Ren , Yan Ziyu , Kwiatkowski Jacek , Lu Yixin 
Published: October 2014

AbstractThe title synthesis represents the first asymmetric application of α‐substituted allenoates in [4 + 1] annulation.
ChemInform Abstract: Dynamic Kinetic Asymmetric [3 + 2] Annulation Reactions of Aminocyclopropanes.
Authors: de Nanteuil Florian , Serrano Eloisa , Perrotta Daniele , Waser Jerome 
Published: October 2014

AbstractThe title reaction proceeds with both enol ethers and aldehydes using Cu and a commercially available bisoxazoline ligand.
ChemInform Abstract: Bromodimethylsulfonium Bromide (BDMS)‐Catalyzed Synthesis of Substituted Pyrroles Through a One‐Pot Four‐Component Reaction.
Authors: Bagdi Prasanta Ray , Basha R. Sidick , Lal Mohan , Khan Abu T. 
Published: October 2014

AbstractA great variety of pyrroles [(V), (VIII), and (X)] is conveniently and ecofriendly synthesized.
ChemInform Abstract: Synthesis of Benzimidazo[2,1‐b]benzothiazole Derivatives Through Sequential Cu‐Catalyzed Domino Coupling and Pd‐Catalyzed Suzuki Reaction.
Authors: Gao Jilong , Zhu Jiaoyan , Chen Lubin , Shao Yingying , Zhu Jiaqi , Huang Yijia , Wang Xiaoxia , Lv Xin 
Published: October 2014

AbstractA convenient protocol for the copper‐catalyzed domino coupling of ortho‐dihaloarenes with 2‐mercaptobenzimidazoles to produce a variety of benzimidazobenzothiazoles is presented.
ChemInform Abstract: α‐Fused Dithienyl BODIPYs Synthesized by Oxidative Ring Closure.
Authors: Heyer Elodie , Retailleau Pascal , Ziessel Raymond 
Published: October 2014

AbstractA novel type of near‐IR dyes (II) is developed using a novel FeCl3‐promoted oxidative ring‐closure of BODIPY precursors that occurs exclusively in the α,α′‐position.
ChemInform Abstract: Palladium‐Catalyzed Carboboration: Borylative Coupling of Alkynes with Alkenes Through Activation of Boron—Chlorine Bonds.
Authors: Nakada Kanayo , Daini Masaki , Suginome Michinori 
Published: October 2014

AbstractTerminal and alkyl‐substituted alkynes do not give the corresponding products.
ChemInform Abstract: Phosphomolybdic Acid Promoted Kabachnik—Fields Reaction: An Efficient One‐Pot Synthesis of α‐Aminophosphonates from 2‐Cyclopropylpyrimidine‐4‐carbaldehyde.
Authors: Reddy Pogula Sreekanth , Reddy Peddiahgari Vasu Govardhana , Reddy Sura Mallikarjun 
Published: October 2014

AbstractPhosphomolybdic acid is an efficient catalyst for the three‐component condensation of pyrimidin‐4‐carbaldehyde, phosphites, and aromatic amines.
ChemInform Abstract: Two New Avermectin Derivatives from the Beibu Gulf Gorgonian Anthogorgia caerulea.
Authors: Gao Chenghai , Wang Yibing , Chen Yinning , He Bijuan , Zhang Rongcan , Xu Mingben , Huang Riming 
Published: October 2014

AbstractTwo new avermectin derivatives, avermectin B1c (Ia) and B1e (Ib) are isolated along with the known compounds, avermectin B2a and ivermectin A1a.
ChemInform Abstract: Lab‐on‐a‐chip Devices for Gold Nanoparticle Synthesis and Their Role as a Catalyst Support for Continuous Flow Catalysis
Authors: Navin Chelliah V. , Krishna Katla Sai , Theegala Chandra S. , Kumar Challa S. S. R. 
Published: October 2014

AbstractReview: 168 refs.
ChemInform Abstract: Recent Progress in the Preparation of Polyaniline Nanostructures and Their Applications in Anticorrosive Coatings
Authors: Tian Zhifei , Yu Haojie , Wang Li , Saleem Muhammad , Ren Fujie , Ren Pengfei , Chen Yongsheng , Sun Ruoli , Sun Yubiao , Huang Liang 
Published: October 2014

AbstractReview: 148 refs.
Targeting Promoter G‐Quadruplex DNAs by Indenopyrimidine‐Based Ligands
Authors: Diveshkumar K. V. , Sakrikar Saaz , Harikrishna S. , Dhamodharan V. , Pradeepkumar P. I. 
Published: October 2014

AbstractThe formation of G‐quadruplex structures can regulate telomerase activity and the expression of oncogenes at the transcriptional and translational levels. Therefore, stabilization of G‐quadruplex DNA structures by small molecules has been recognized as a promising strategy for anticancer drug therapy. One of the major challenges in this field is to impart stabilizing molecules with selectivity toward quadruplex structures over duplex DNAs, and to maintain specificity toward a particular quadruplex topology. Herein we report the synthesis and binding interactions of indenopyrimidine derivatives, endowed with drug‐like properties, with oncogenic promoters of c‐myc and c‐kit, telomeric and duplex DNAs. The results show specific stabilization of promoter over telomeric quadruplexes and duplex DNAs. Molecular modeling studies support the experimental observations by unraveling the dual binding mode of ligands by exploiting the top and bottom quartets of a G‐quadruplex structure. This study underscores the potential of the indenopyrimidine scaffold, which can be used to achieve specific G‐quadruplex‐mediated anticancer activity.