bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of Albuminuria on Early Neurological Deterioration and Lesion Volume Expansion in Lenticulostriate Small Infarcts
Authors: Umemura Toshitaka , Senda Joe , Fukami Yuki , Mashita Shinichi , Kawamura Takahiko , Sakakibara Toshimasa , Sobue Gen 
Published: December 2013

Background and Purpose—
Albuminuria, a marker of chronic kidney disease, is associated with an increased risk of incident stroke and unfavorable long-term outcomes. However, the association of albuminuria with short-term outcomes and change in infarct volume in patients with acute small subcortical infarction remains unknown.

Methods—
We retrospectively reviewed 85 consecutive patients with acute small subcortical infarcts in the lenticulostriate artery territory who were admitted to our stroke center within 24 hours of symptom onset and underwent serial diffusion-weighted imaging (DWI). Albuminuria was determined based on the urinary albumin-to-creatinine ratio obtained from a first morning spot urine after admission. Infarct volume was measured on axial sections of the initial and follow-up DWI. Early neurological deterioration (END) was defined as an increase of ≥2 points in the National Institutes of Health Stroke Scale score during the first 5 days after admission.

Results—

Albuminuria (UACR ≥30 mg/g creatinine) was observed in 14 of 18 patients with END (77.8%) and in 25 of 67 patients without END (37.3%),
P
=0.002. Multivariate logistic regression analysis revealed that albuminuria was associated with END after adjustment for age, low estimated glomerular filtration rate (<60 mL/min per 1.73 m
2
), and infarct volume on initial DWI (odds ratio, 6.64; 95% confidence interval, 1.62–27.21;
P
=0.009). In addition, albuminuria was an independent predictor of increase in infarct volume using multivariate linear regression analysis (
β
coefficient=0.217;
P
=0.038).

Conclusions—
Our findings suggest that albuminuria is associated with END and infarct volume expansion in patients with small subcortical infarcts in the lenticulostriate artery territory.
L’aspect exprimé par le suffixe chû ‘en cours de’ en japonais
Authors: Oshima Hiroko 
Published: December 2013

This paper focuses on the aspectual value of the Sino-Japanese suffix -chû ‘in the process of’. It argues that the aspectual meaning and function of -chû differ from those expressed by the continuative aspect marker -teiru, and that these differences may be accounted for by the semantics of -chû. When suffixed to a verbal noun, -chû can only denote a temporary or a momentary activity, whereas -teiru can also denote an habitual and regular activity. When denoting a resultative state, -chû, unlike -teiru, implies a right boundary, and marks the state as temporary. Finally, unlike -teiru, -chû highlights the momentary nature of the event or state in question, so that, depending on the context, it can trigger the readings of ‘opportunity to be seized’ or ‘temporary prohibition’.   Nous montrons ici que l’aspect exprimé par le suffixe sino-japonais -chû ‘en cours de’ diffère de celui marqué par la forme en -teiru (marqueur d’aspect continuatif), et que ces différences sont dues au sémantisme du suffixe -chû. Quand il suffixe un nom verbal, -chû n’exprime qu’une activité temporaire et momentanée, alors que -teiru peut également marquer une activité habituelle et régulière. L’état résultant exprimé par chû est borné à droite et considéré comme temporaire, à la différence de l’état résultant marqué par -teiru. On constate également avec -chû un phénomène de saillance liée à la nature temporaire de l’intervalle, qui donne naissance suivant le contexte à diverses interprétations d’occasion à saisir, ou au contraire d’interdiction provisoire d’accès, qui le distinguent aussi de -teiru.
Can screening 4–5 year olds accurately identify children who will have teacher-reported mental health problems when children are aged 6–7 years?
Authors: Sawyer Alyssa CP , Chittleborough Catherine R , Lynch John W , Baghurst Peter , Mittinty Murthy N , Kaim Amy LE , Sawyer Michael G 
Published: December 2013

Objective: To assess the screening accuracy of information obtained from parents of 4–5-year-old children for the purpose of identifying the children who have teacher-reported mental health problems when they are aged 6–7 years. Method: The study used data from the Longitudinal Study of Australian Children (LSAC) obtained when children were aged 4–5 years and 6–7 years. The level of children’s mental health problems was assessed using the Strengths and Difficulties Questionnaire (SDQ) completed by parents when children were aged 4–5 years and by teachers when children were aged 6–7 years ( n=2163). When children were aged 4–5 years, parenting skills were assessed using three questionnaires developed for the parent-completed LSAC questionnaire and maternal mental health was assessed using the Kessler Psychological Distress Scale (K6). Results: When the level of parent-reported childhood mental health problems at 4–5 years old was used to identify children with teacher-reported mental health problems (i.e. a score in the “abnormal” range of the teacher-reported SDQ Total Difficulties Scale) when the children were aged 6–7 years, sensitivity was 26.8%, positive predictive value was 22.8%, and specificity was 92.9%. The addition of further information about the characteristics of children and their parents made only a small improvement to screening accuracy. Conclusions: Targeted interventions for preschool children may have the potential to play an important role in reducing the prevalence of mental health problems during the early school years. However, current capacity to accurately identify preschoolers who will experience teacher-reported mental health problems during the early school years is limited.
Freedom of information reform in China: information flow analysis
Authors: Xiao Weibing 
Published: December 2013

Freedom of Information (FOI) in China has been approached as a strange and intriguing phenomenon. This article uses information flow analysis to propose a more detailed understanding of China’s FOI reform. Information flow, a theme to explore the gradual development of government receptivity to FOI in an information environment through time, is used as a new explanatory model for China’s FOI reform. This article argues that the reform is an outcome of improved information flow resulting from social, political, legal and economic factors. It also asserts that social, political and legal factors should be accorded a central role in understanding the development of FOI in China. Furthermore, China’s FOI reform formed part of a much longer process of increased transparency in the Chinese information environment. This is the reason China has adopted a model of FOI legislation stressing proactive disclosure. Points for practitioners The adoption of FOI legislation in China presents a special case study for FOI practitioners, that is, FOI officers. The practitioners face the challenge of processing information requests in an authoritarian regime. This article provides a more complete answer to the paradox of China’s FOI phenomenon. It focuses on local information flow conditions, and this provides a new perspective for FOI practitioners to understand China’s FOI reform. By applying information flow analysis, it argues that China’s FOI reform is an outcome of improved information flow resulting from social, political, legal and economic factors. This resulted in China adopting a model of FOI legislation emphasizing proactive disclosure. A complete and accurate understanding of this reform could help FOI practitioners to improve China’s FOI performance from the perspective of information flow.
Language, listening and learning: critically reflective accountability for INGOs
Authors: Crack Angela Maria 
Published: December 2013

This article examines the emergence of two waves of reforms across the international non-government organization (INGO) sector in accountability discourse and practice. The first wave accountability model was narrowly framed around the demands of powerful stakeholders such as donors and governments, whereas the second wave was a more holistic approach that prioritized the obligations of INGOs towards their ‘beneficiaries’. It is argued that INGOs should embed critically reflective accountability by pursuing further reforms in three thematic areas. First, words such as ‘beneficiary’ should be expunged from the language of accountability, since it is encoded with norms that implicitly undermine the rights of people and communities to expect that INGOs should be answerable for their actions. Second, listening to marginalized stakeholders should be facilitated by inclusive discursive arenas that enable and empower people ‘to speak and be heard’. Lastly, INGOs need to use feedback to become a learning organization, and collaborate with peers to engender a culture of reflective learning across the sector. Points for practitioners The article offers several policy recommendations structured around three core themes. These include suggestions for the training of field staff, issues concerning the design of participatory exercises, and proposals for a strengthened regime of peer-regulation.
Leading the world: Public sector reform and e-government in Korea
Authors: O’Donnell Michael , Turner Mark 
Published: December 2013

AbstractAn integral component of public management reform in Korea has been e-government, a field in which Korea has been a pioneer and in which it is the world leader. This article examines the Korean model of public management reform in the context of the developmental state and democratisation to describe and explain the emergence and expansion of e-government practices. The growth of e-government is tracked and the crucial role of the Ministry of Public Administration and Security delineated. Also covered are Government for Citizens initiatives, the provision of particular services, the mushrooming use of smart phones and emerging patterns of citizen participation, especially as related to local-level governance. The article demonstrates how much can be achieved in e-government and provides a model from which other countries can choose appropriate practices.
Beyond the illusion of numbers: A challenge for financial regulators and analysts
Authors: Royal Carol , O’Donnell Loretta 
Published: December 2013

AbstractGlobal financial crises and potential sovereign defaults provide an opportunity for financial regulators and analysts to revise assumptions in their risk models. These conditions are also an opportunity for regulators and analysts to distinguish the ‘hyper-real’ economy, represented by derivatives, from the real economy, which requires assessment through an analysis of human as well as financial capital. Regulators are required to demonstrate that they are skilled in conducting the most thorough analysis of all elements of the finance system in order to help the investing public to manage risk as much as possible. The contribution of this article is to overview the limitations inherent in regulators’ traditional focus on financial analysis, as well as in financial analysts’ failure to consider the relevance of people management data when evaluating the potential performance of knowledge-intensive, service-based organisations. The article argues for a stronger focus on analysis of non-financial capital, including human capital, to provide a more effective ‘early warning’ of potential financial distress.
Public sector management and the changing nature of the developmental state in Korea and Malaysia
Authors: Turner Mark , O’Donnell Michael , Suh Chung-Sok , Kwon Seung-Ho 
Published: December 2013

AbstractThis article traces the role of the state in developmental theory and practice, paying particular attention to public sector management. The early orthodoxy of modernisation theory put the state at the centre of development, giving it prime responsibility for generating development. Realisations of the shortcomings of modernisation theory and disappointment with its results led to the rise of neoliberal approaches in development thinking and action, with a focus on the shrinking state. However, in turn, the efficacy of neoliberalism has been questioned, and its human toll has been critiqued. Coupled with evidence of the success of the East Asian developmental states, the result has been a rethinking of the state and a new acknowledgment of its central role in development. Strong institutions and efficient, effective and responsive public sector management have been identified as key ingredients of capable states that made development happen. In outlining this trajectory, the article introduces the case studies that comprise this symposium.
A Favorable Course of Palliative Sedation
Authors: Brinkkemper Tijn , Rietjens Judith A. C. , Deliens Luc , Ribbe Miel W. , Swart Siebe J. , Loer Stephan A. , Zuurmond Wouter W. A. , Perez Roberto S. G. M. 
Published: December 2013

Objective: Comparing characteristics of a favorable sedation course during palliative sedation to a less favorable course based on the reports Dutch physicians and nurses. Results: Cases identified as having a favorable sedation course less often concerned a male patient ( P = .019 nurses’ cases), reached the intended sedation depth significantly quicker ( P < .05 both nurses and physicians’ cases), reached a deeper level of sedation ( P = .015 physicians’ cases), and had a shorter total duration of sedation compared ( P < .001 physicians’ cases) to patients with a less favorable sedation course. Conclusions: A favorable course during palliative sedation seems more probable when health care professionals report on a (relatively) shorter time to reach the required depth of sedation and when a deeper level of sedation can be obtained.
CD33 target validation and sustained depletion of AML blasts in long-term cultures by the bispecific T-cell–engaging antibody AMG 330
Authors: Krupka Christina , Kufer Peter , Kischel Roman , Zugmaier Gerhard , Bögeholz Jan , Köhnke Thomas , Lichtenegger Felix S. , Schneider Stephanie , Metzeler Klaus H. , Fiegl Michael , Spiekermann Karsten , Baeuerle Patrick A. , Hiddemann Wolfgang , Riethmüller Gert , Subklewe Marion 
Published: December 2013

Key PointsCD33 expression levels in AML correlate with specific disease characteristics. Potent cytotoxicity against primary AML blasts is mediated by a CD33/CD3-bispecific antibody.
Contact activation products are new potential biomarkers to evaluate the risk of thrombotic events in systemic lupus erythematosus
Authors: Bäck Jennie , Lood Christian , Bengtsson Anders A , Ekdahl Kristina Nilsson , Nilsson Bo 
Published: December 2013

Abstract
Introduction
Patients with systemic lupus erythematosus (SLE) have persistent platelet activation and an increased risk of thrombotic events, which cannot be accounted for by traditional cardiovascular risk factors. Factor (F)XII has a potentially important role in thrombus formation and is triggered by activated platelets. We therefore asked whether the contact system is involved in inflammation and vascular disease (VD) in SLE.

Methods
Fibrin clots were incubated with purified FXII or whole blood, and the activation and regulation of FXII were studied. Plasma from SLE patients with (n = 31) or without (n = 38) previous VD and from matched healthy controls (n = 68) were analyzed for the presence of complexes formed between contact system enzymes and antithrombin (AT) or C1 inhibitor (C1INH) and evaluated with regard to clinical data and laboratory parameters.

Results
Fibrin clots elicited FXII activation and acted as co-factors for AT. In clotting plasma, the levels of FXIIa-AT increased, and FXIIa-C1INH decreased. A similar reciprocal relationship existed in SLE patients. FXIIa-AT was elevated in the SLE patients with a history of VD, while the corresponding levels of factor FXIIa-C1INH were significantly decreased. FXIIa-AT correlated strongly with platelet parameters. The odds ratio for VD among the SLE patients was 8.9 if they had low levels of FXIIa-C1INH, 6.1 for those with high levels of FXIIa-AT, and increased to 23.4 for those with both decreased levels of FXIIa-C1INH and increased levels of FXIIa-AT.

Conclusions
Activation of FXII is elicited by fibrin during thrombotic reactions in vitro and in vivo, and fibrin acts as a heparin-like co-factor and regulates AT. Patients with SLE had altered levels of FXIIa-serpin complexes, supporting that the contact system is involved in this disease. FXIIa-serpin complexes are strongly associated with previous VD in SLE patients, suggesting that these complexes are potential biomarkers for monitoring and assessing the risk of thrombotic events in SLE.
Amplicon pyrosequencing and ion torrent sequencing of wild duck eubacterial microbiome from fecal samples reveals numerous species linked to human and animal diseases
Authors: Strong Thomas , Dowd Scot , Gutierrez Alexander F. , Molnar David , Coffman Jonathan 
Published: December 2013

Our investigation into the composition of the wild duck,Aythya americana, eubacterial microbiome from a fecal sample using amplicon pyrosequencing revealed that the representative bacterial species were quite distinct from a pond water sample, and we were able to classify the major operational taxonomic units withFusobacterium mortiferum,Streptobacillus moniliformis,Lactobacillus intermedius,Actinomyces suimastitidis,Campylobacter Canadensis,Enterococcus cecorum,Lactobacillus aviarus,Actimomyces spp.,Pseudobutyrivibrio spp.and Helicobacter brantaerepresenting the majority of the eubacterial fecal microbiome. Bacterial species present in the analysis revealed numerous organisms linked to human and animal diseases including septicemia, rat bite fever, pig mastitis, endocarditis, malar masses, genital infections, skin lesions, peritonitis, wound infections, septic arthritis, urocystitis, gastroenteritis and drinking water diseases. In addition, to being known carriers of viral pathogens wild ducks should also be recognized as a potential source of a range of bacterial diseases.
Families of Individuals With Intellectual and Developmental Disabilities: Policy, Funding, Services, and Experiences
Authors: Hewitt Amy , Agosta John , Heller Tamar , Williams Ann Cameron , Reinke Jennifer 
Published: December 2013

Abstract
Families are critical in the provision of lifelong support to individuals with intellectual and developmental disabilities (IDD). Today, more people with IDD receive long-term services and supports while living with their families. Thus, it is important that researchers, practitioners, and policy makers understand how to best support families who provide at-home support to children and adults with IDD. This article summarizes (a) the status of research regarding the support of families who provide support at home to individuals with IDD, (b) present points of concern regarding supports for these families, and (c) associated future research priorities related to supporting families.
New Transnational Governance and the Changing Composition of Regulatory Pluralism in Southeast Asia
Authors: Gillespie John 
Published: December 2013

AbstractOver the past three decades, Transnational Production Regimes (TPRs) have become the main source of technical and regulatory knowledge for Southeast Asia corporations. Typically TPRs transfer knowledge from lead firms located in the industrial North to supplier firms located in Southeast Asia. Regulatory knowledge transferred through TPRs largely bypasses Southeast Asian laws and legal institutions to directly influence the behavior of supplier firms. Although socio-economic studies show that TPRs are responsible for generating much wealth creation in the region, they hardly register in the socio-legal literature. Drawing on ethnographic studies conducted in Vietnam, this paper will attempt to explain why different types of TPRs produce different regulatory responses in Vietnamese firms. Preliminary findings suggest differences in the way that regulatory knowledge transmitted through Northeast Asian and Euro-American TPRs is absorbed and integrated into the organisational fabric of Vietnamese firms. They also shed light on two well-documented phenomena in Vietnam. In conclusion the paper will argue that TPRs displace state commercial laws and are partially responsible for the slow progress of conventional law and development projects in changing regulatory practices. It will contend that the different kinds of TPRs generate regulatory pluralism and the uneven application of state law in different business sectors.
Zur Verortung Öffentlicher Bibliotheken auf den Homepages ihrer Kommunen – eine empirisch-quantitative Beschreibung
Authors: Nikolaizig Andrea , Süßkraut Anne 
Published: December 2013

Zusammenfassung:
Der Internet-Auftritt einer Kommune ist eine etablierte Informationsquelle für ihre BürgerInnen oder Gäste über die jeweiligen kommunalen Angebote, Leistungen und Services. Es ist zu erwarten, dort auch die Öffentliche Bibliothek zu finden. Doch wie: direkt oder unter welchen Begriffen? Diese Untersuchung interessiert sich für die begriffliche Verortung der Öffentlichen Bibliotheken auf den Homepages (Startseiten) kommunaler Internet-Auftritte. Dazu wurden 1.557 kommunale Homepages besucht. Wenige Bibliotheken sind auf der Homepage unter dem Begriff „Bibliothek“ verlinkt. In der Mehrzahl der Fälle muss der Seitenbesucher die Bibliothek unter übergeordneten Begriffen oder Begriffspaaren denken. Die begriffliche Zuordnung ist nicht unerheblich, weil sie der Bibliothek eine funktionale Dominanz wie Kultur, Bildung, Freizeit, Tourismus, Verwaltung usw. zuweist. Sie leistet damit einen Beitrag zur Kommunikation der Bibliotheks-Philosophie in der Öffentlichkeit und wird von dieser entsprechend wahrgenommen.
Politique familiale et fécondité en Norvège : une question de genre et de classe sociale
Authors: Lise Ellingsæter Anne , Pedersen Eirin 
Published: December 2013

Family policy and fertility in Norway : a gender and class perspective.
What importance do young adults attribute to family policy arrangements in the choice about having children ? Does family policy feature differently in the reasoning among women and men and across social classes ? This qualitative study of 90 young adults in Norway finds that contrary to common expectations, young adults consider family policy arrangements being of little impact on their own choice to have a child. But this apparent insignificance paradoxically may be the strongest evidence of how crucial it actually is. The policy arrangements are being taken for granted, ingrained in young adults’ horizon of expectations : Welfare state arrangements constitute a key foundation of the organisation of parenthood, based on a dual earner provider model.