bluuebunny/crossref_metadata_2025_split huggingface dataset:
Foreign Bodies Associated With Peri‐Implantitis Human Biopsies
Authors: Wilson Thomas G. , Valderrama Pilar , Burbano Maria , Blansett Jonathan , Levine Robert , Kessler Harvey , Rodrigues Danieli C. 
Published: September 2014

Background: Peri‐implantitis is an inflammatory condition that can lead to implant loss. The aim of this descriptive retrospective study is to describe the histopathologic findings in soft tissue biopsies of implants with peri‐implantitis.Methods: Thirty‐six human peri‐implantitis biopsies were analyzed using light microscopy (LM) and scanning electron microscopy (SEM). The composition of foreign materials found in the tissues was assessed using an energy dispersive x‐ray spectrometer.Results: At the LM level, the inflammatory lesion of peri‐implantitis was in most cases a mixture of subacute and chronic inflammation dominated by plasma cells. At the SEM level, radiopaque foreign bodies were identified in 34 of the 36 biopsies. The predominant foreign bodies found were titanium and dental cement. These foreign materials were surrounded by inflammatory cells.Conclusions: At present, the exact mechanism for introduction of these materials and their role in peri‐implantitis is unknown. Further research is warranted to determine their etiology and potential role in pathogenesis.
Prototype Test of an All-Electric Intelligent-Completion System for Extreme-Reservoir-Contact Wells
Authors: Bouldin Brett , Verma Chandresh , Bellaci Isidore , Black Michael , Dyer Steve , Algerøy John , De Oliveira Thales , Pan Yulin 
Published: September 2014

Summary
One of the core focus areas in Saudi Aramco's effort to increase hydrocarbon recovery is in the application of extreme-reservoir-contact (ERC) wells. These wells, with more than 20 km of reservoir contact, are needed to ensure fluid off-take points are distributed throughout the reservoir efficiently. Accurate sensing and control are crucial to the efficient sweep of heterogeneous formations. This paper describes a recent multilateral (ML)-well trial that validated a number of core technologies and methods required to make ERC a reality, including
Well construction and deployment practices to allow electrical umbilicals to be reliably deployed in openhole laterals Deployment and testing of revolutionary low-power, infinitely positioned electric flow-control valves (FCVs) designed to be deployed in each compartment in an openhole segmented lateral completion Validation of the fully integrated onboard-production-monitoring system providing direct downhole measurements of pressures, temperatures, flow rates, and water cut for each controlled compartment Integration of the surface acquisition and monitoring system to the production supervisory-control-and-data-acquisition (SCADA) system to provide real-time downhole production information, as well as valuable system-health-status data that can ensure operational integrity during the life cycle of the well
An ML well close to the oil/water-contact point was allocated to validate the functionality of two prototype systems installed and has provided valuable reservoir data for more than 1 year of production. The well trial successfully demonstrated the ability to install and retrieve an umbilical completion from a 10,000-ft horizontal lateral. The ability to control downhole flow to within a few barrels per day measured at the reservoir face is proving revolutionary to the way the operator will approach future reservoir management. The sensing system will be capable of delivering continuous compartment productivity. The SCADA integration allows for a real-time management function such that the compartment can be controlled to a target off-take rate directly, without resorting to the use of traditional well-system models for estimating control settings. This paper highlights the objectives, installation, validation, and functional aspects of this new ERC well system, as well as identifying some of the immediate production effects emerging from this level of visibility and control at the formation face.
Optimization of Uncertain Structural Parameters With Production and Observation Well Data
Authors: Irving A.D.. D. , Kuznetsov D.. , Robert E.. , Manzocchi T.. , Childs C.J.. J. 
Published: September 2014

Summary
The conditioning of fault geometry and properties to production data is usually achieved by ad hoc modifications without considering prior probability distributions or physical realism. We investigate optimization approaches on the basis of response surfaces and the ensemble Kalman filter (EnKF), on a reservoir of which the structure, well pattern, and production history make it particularly suitable. The observed pressure behavior during buildup and interference periods demonstrates production induced across fault communication. This behavior was best matched by reducing the reservoir volume and fault offset compared with the base-case interpretation, but with fault properties close to the a priori base case.
High-Strength, High-Stability Pill System To Prevent Lost Circulation
Authors: Xu Cheng-yuan , Kang Yi-li , You Li-jun , Li Song , Chen Fei 
Published: September 2014

Summary
A high-strength, high-stability (HSHS) pill system for controlling lost circulation has been developed and optimized on the basis of a physical model of a stable plugged zone. This HSHS pill system provides a stronger and more-effective seal than traditional treatments.
Controlling lost circulation with a plugged zone formed with lost-circulation material (LCM) in the fracture has achieved tremendous success in past years. However, investigation into the strength and stability of the plugged zone has not been reported. Lack of such knowledge often leads to excess costs from repeated fluid loss and rig time; it increases the difficulty and complexity of loss-zone diagnosis.
The new HSHS pill system addresses these shortcomings. Surface-friction coefficient, LCM volume fraction, and amount of contact deformation are the main influencing factors of the strength and stability of the plugged zone. The strength of the plugged zone is enhanced with the increase of the above factors. A physical model for stable plugged zone is established considering the three factors. The pill system that is based on the model provides an engineered combination of rigid granules, fibers, and resilient particles. The sealing efficiency and the pressure-bearing capacity are greatly enhanced. It was validated in several field trials in west China. Operational practices that facilitate the safe use of the HSHS system with overbalance exceeding 2,174 psi are discussed. In addition to the field-trial results, this paper also describes the laboratory experiments, that were used for developing the new system.
With the development of the physical model and the HSHS pill system, it is now possible to optimize and select the types, properties, and matching relations of the LCM. One can also use this technology to guide the design of the wellbore-strengthening scheme and to make sure of the long-term effectiveness of wellbore-strengthening measures.
Beta-blockers Associated with a Mortality Benefit in Patients with Systolic Dysfunction and Elevated Serum Bilirubin
Authors: Labos Christopher , Nguyen Vivian , Giannetti Nadia , Huynh Thao 
Published: September 2014

Background:Hyperbilirubinemia is associated with increased mortality in heart failure (HF) patients. We evaluated the impact of evidence-based medical therapy, in particular beta-blocker on the survival of patients with HF and hyperbilirubinemia.Methods and Results:We reviewed the charts of all patients followed at our tertiary care heart failure clinic. Hyperbilirubinemia was defined as total bilirubin >30 µmol/L (1.5 times the upper limit of our laboratory value). The primary endpoint was all-cause mortality. The secondary endpoint was a composite of death, cardiac transplant or ventricular assistance device implantation (VAD). Of 1035 HF patients, 121 patients (11.7%) had hyperbilirubinemia. Median follow-up was 556 days. Hyperbilirubinemia was associated with an eight-fold increase in all-cause mortality, hazard ratio (HR): 8.78[95% Confidence Intervals (CI): 5.89-13.06]. Beta-blocker use was associated with approximately 60% reduction in all-cause mortality (HR: 0.38, 95% CI:0.15-0.94) and 70% reduction in the composite secondary endpoint (HR:0.31, 95% CI:0.13-0.71) in patients with hyperbilirubinemia.Conclusion:HF patients with hyperbilirubinemia have increased early mortality, need for cardiac transplantation or VAD. Beta-blocker use was associated with early survival benefit in these patients. Bilirubin levels should be monitored in patients with HF and early initiation of beta-blockers in patients with hyperbilirubinemia should be considered.
Return-to-Work Following Open Reduction and Internal Fixation of Proximal Humerus Fractures
Authors: Dietrich Michael , Wasmer Mathias , Platz Andreas , Spross Christian 
Published: September 2014

Objectives :
Shoulder disorders have an important impact on a patient’s capacity to work. We investigated whether there is a relationship between subjective or objective outcome measures and the ability and time for returning to work (RTW) after a proximal humerus fracture (PHF).

Design :
Retrospective single-centre study from March 2003 to June 2008.

Setting :
City hospital, trauma level one centre.

Intervention :
All PHF stabilized with a PHILOS®.

Main Outcome Measurements :
Routine follow-up examinations (X-ray, Constant-Murley Score (CMS), Short-Form 36 (SF-36)) were performed prospectively after 1.5, 3, 6 and 12 months or until RTW. Primary interest was the comparison of the outcome scores with the time needed for RTW.

Results :
72 patients (52 years (22-64), 37 (51%) women) fulfilled the inclusion criteria. We distinguished “office-workers” (OW) (n = 49, 68%) from patients who worked at a physically demanding job (PW) (n = 23, 32%). Although time for RTW was fundamentally different (42 (OW) vs 118 days (PW), p<0.001), CMS (64.7 vs 64.1) and SF-36 (66.8 vs 69.9) at time of RTW were almost identical. At follow-up, CMS and SF-36 were always lower in the PW group.

Conclusion :
Jobs which require higher physical demands were likely to influence and to delay RTW. This study identifies cut off values for CMS and SF-36 at which a patient feels capable or willing to RTW after PHF. These values show the importance and impact of a patient’s occupation or demands on RTW. We were able to show, that besides age, sex and fracture, the type of occupation might alter the scores in postoperative outcomes.
The Biological Activities of Troponoids and Their Use in Agriculture A Review
Authors: Saniewski Marian , Horbowicz Marcin , Kanlayanarat Sirichai 
Published: September 2014

Abstract
Chemical compounds containing the tropone structure (2,4,6-cycloheptatrien-1-one), in their molecule, called troponoids, characterized by a seven-membered ring, are distributed in some plants, bacteria and fungi, although they are relatively rare. ß-Thujaplicin (2-hydroxy-4-isopropyl-2,4,6-cycloheptatrien-1-one), also known as hinokitiol, is a natural compound found in several plants of the Cupressaceae family. Besides hinokitiol, related compounds were identified in Cupressaceae trees. It has been demonstrated that hinokitiol and its derivatives have various biological effects, such as antibacterial, antifungal, insecticidal, antimalarial, antitumor, anti-ischemic, iron chelating and the inhibitory activity against polyphenol oxidase activity. Activity similar to ß-thujaplicin has tropolone and its derivatives, which are not present nature. Due to the high scientific and practical interest, synthetic ß-thujaplicin and other troponoids have been produced for many years. In this review, the major biological effects of troponoids, mostly ß-thujaplicin and tropolone, on tyrosinase and polyphenol oxidase activity, ethylene production, antibacterial, antifungal and insecticidal activities, and biotransformation of ß-thujaplicin by cultured plant cells are presented. Accumulation of ß-thujaplicin and related troponoids has been shown in cell cultures of Cupressus lusitanica and other species of Cupressaceae. The biosynthetic pathway of the troponoids in plants, bacteria and fungi has been also briefly described.
Micropropagation of PLUCHEA LANCEOLATA (Oliver & Hiern.) Using Nodal Explant
Authors: M. Kher Mafatlal , Joshi Dimpal , Nekkala Sureshkumar , Nataraj M. , P. Raykundaliya Dharmesh 
Published: September 2014

Abstract

Pluchea lanceolata is an important medicinal plant of Asteraceae family known for its anti-arthritic and anti-inflammatory activity. A protocol was established for micropropagation of P. lanceolata using nodal explants. Nodal explants were inoculated onto Murashige and Skoog (1962) - MS medium supple–mented with 6-benzylaminopurine (BAP), kinetin (Kin), thidiazuron (TDZ) and 2iP (2-isopentenyladenine) at various concentrations (0.0, 0.5, 1.0, 1.5 and 2.0 mg·dm-3). The highest multiplication rate was obtained for nodal explants cultured on MS medium, supplemented with 0.5 mg·dm-3 thidiazuron (TDZ). In vitro raised shoots were successfully rooted on ½ mineral salt concentration of MS medium supplemented with 1.0 mg dm-3 IBA.
Effect of 8-Hydroxyquinoline Citrate, Sucrose and Peroxidase Inhibitors on Vase Life of Lisianthus (EUSTOMA GRANDIFLORUM L.) Cut Flowers
Authors: Sharifzadeh Kamaladin , Asil Moazzam Hassanpour , Roein Zeynab , Sharifzadeh Muhammad 
Published: September 2014

Abstract
Cut lisianthus flowers have a short vase life, possibly due to blockage of xylem vessels. The effect of 8-hydroxyquinoline citrate, sucrose and peroxidase inhibitors on delaying senescence and extending vase life of cut lisianthus flowers was tested. The peroxidase inhibitors used in this experiment were catechol (CH) (5, 10, 15 mM) and p-phenylenediamine (PD) (5, 10, 15 mM). All vase solutions contained 200 mg-dm-3 8-hydroxyquinoline citrate (8-HQC) and 3% sucrose. 10 mM CH treatment was the most effective for vase life extension (13.3 days), increasing water uptake, and delaying fresh weight loss. The vase solution containing 10 mM CH significantly increased superoxide dismutase (SOD) and decreased peroxidase (POD) activities. Similarly, 10 mM PD increased anthocyanin content more than the other treat–ments. Protein degradation was significantly delayed by application of 5 mM PD. The malondialdehyde (MDA) accumulation was reduced when CH at 5 mM and PD in 5 and 15 mM were added to the vase solution. Results indicated that peroxidase inhibitors in combination with 8-HQC and sucrose increase vase life of lisianthus by improving water uptake and delaying fresh weight loss.
The Impact of the Brassicaceae Plant Materials Added to the Soil on the Population of FUSARIUM SOLANI (Mart.) SACC. and FUSARIUM OXYSPORUM Schlecht
Authors: Smolińska Urszula , Kowalczyk Waldemar 
Published: September 2014

Abstract
Soil with the spores of fungi in dormant stage from previous years infections belonging to the genus Fusarium caused significant loss of onion yield in Poland. The most important form of Fusarium inoculum in the field are chlamydospores, which may survive in soil for many years. There are no available methods to eradicate chlamydospores from soil environment. Inspired by data from the literature and own prelimi–nary observation, we evaluated the effect of application of Brassicaceae plant material to the soil infested with F. oxysporum and F. solani isolates, which are pathogenic to onion. Obtained results showed that addition of fresh plant material from B. juncea and B. alba had no effect on amount of Fusarium propagules in the soil. Moreover amendment of infested soil with dry plants or milled seeds of B. juncea or B. nigra significantly stimulated the population of Fusarium in the soil.
White matter architecture of the language network
Authors: Kljajevic Vanja 
Published: September 2014

AbstractThe relevance of anatomical connectivity for understanding of the neural basis of language was recognized in the 19th century, and yet this topic has only recently become the subject of wider research interest. In this paper, I review recent findings on white matter tracts implicated in language: the arcuate fasciculus, superior longitudinal fasciculus, extreme capsule, uncinate fasciculus, middle longitudinal fasciculus, inferior longitudinal fasciculus, and inferior fronto-occipital fasciculus. The reviewed findings on these tracts were reported in studies that used a variety of methods, from post-mortem dissection and diffusion imaging to intraoperative electrostimulation with awake surgery patients. The emerging picture suggests that there is currently no consensus with regard to the exact number and identity of the tracts supporting language, their origins, trajectories, and terminations, as well as their functional interpretation.
As traduções literárias nas relações culturais romeno-portuguesas
Authors: Manole Veronica , Vasile Iolanda 
Published: September 2014

Abstract
This article outlines the importance of the role played by literary translations in the Romanian - Portuguese cultural relations. We develop our analysis based on two criteria: the historical-political context and the Western literary canon. We further focus on translations from nine writers, completing our research with views from a few of the main translators on both sides.
Microspore development in Annona (Annonaceae): Differences between monad and tetrad pollen
Authors: Lora Jorge , Herrero Maria , Hormaza Jose I. 
Published: September 2014

• Premise of the study: Permanent tetrads are the most common form of pollen aggregation in flowering plants. The production of pollen in monads is plesiomorphic in angiosperms, but the aggregation into tetrads has arisen independently different times during the evolution of flowering plants. The causes behind the recurrent evolution of pollen aggregation from monads remain elusive. Permanent tetrad pollen is quite common in the Annonaceae, the largest family in the early‐divergent order Magnoliales. In some genera, such as Annona, both tetrad‐ and monad‐producing species can be found.• Methods: In this comparative study of pollen development, we use immunolocalization, cytological characterization, and enzymatic assays of four species in the genus Annona and one species in its closely related genus Asimina that release pollen in tetrads and two species in the genus Annona that release pollen in monads.• Key results: The main difference between species with tetrad and monad pollen is a delayed digestion of callose and cellulose at the pollen aperture sites that resulted in nonlayering of the exine in these areas, followed by a rotation and binding of the young microspores at the aperture sites.• Conclusions: Small changes in development resulted in clear morphological changes on pollen dispersal time and open a window on the possible selective advantage of the production of aggregated pollen.
What Matters Most for Patients, Parents, and Clinicians in the Course of Juvenile Idiopathic Arthritis? A Qualitative Study
Authors: Guzman Jaime , Gómez-Ramírez Oralia , Jurencak Roman , Shiff Natalie J. , Berard Roberta A. , Duffy Ciaran M. , Oen Kiem , Petty Ross E. , Benseler Susanne M. , Brant Rollin , Tucker Lori B. 
Published: September 2014

Objective.To assess which clinical features are most important for patients, parents, and clinicians in the course of juvenile idiopathic arthritis (JIA).Methods.Forty-nine people participated in 6 audience-specific focus group discussions and 112 reciprocal interviews in 3 Canadian cities. Participants included youth with JIA, experienced English- and French-speaking parents, novice parents (< 6 mos since diagnosis), pediatric rheumatologists, and allied health professionals. Participants discussed the importance of 34 JIA clinical features extracted from medical literature. Transcripts and interview reports underwent qualitative analysis to establish relative priorities for each group.Results.Most study participants considered medication requirements, medication side effects, pain, participant-defined quality of life, and active joints as high priority clinical features of JIA. Active joint count was the only American College of Rheumatology core variable accorded high or medium priority by all groups. Rheumatologists and allied health professionals considered physician global assessment as high priority, but it had very low priority for patients and parents. The parent global assessment was considered high priority by clinicians, medium to high by parents, and low by patients. Child Health Assessment Questionnaire scores were considered low priority by patients and parents, and moderate or high by clinicians. The number of joints with limited motion was given low to very low priority by all groups. Parents gave high priority to arthritis flares.Conclusion.If our findings are confirmed, medication requirements, medication side effects, pain, participant-defined quality of life, and active joint counts should figure prominently in describing the course of JIA.
Immunosuppressive Therapies for the Induction Treatment of Proliferative Lupus Nephritis: A Systematic Review and Network Metaanalysis
Authors: Tian Simon Yu , Feldman Brian M. , Beyene Joseph , Brown Patrick E. , Uleryk Elizabeth M. , Silverman Earl D. 
Published: September 2014

Objective.To evaluate and determine the most effective immunosuppressive therapy for the induction treatment of proliferative lupus nephritis (PLN) based on renal remission.Methods.A systematic review of randomized controlled trials was conducted. The outcomes were renal remission at 6 months: (1) normalization of serum creatinine [(sCr), or within 15% of the normal range, i.e., sCr < 132µmol/l — creatinine remission]; and (2) proteinuric remission (prU < 0.5 g/day/1.73m2). A Bayesian network metaanalysis was used.Results.The OR (95% credible interval) of inducing an sCr remission at 6 months was 1.70 (0.51, 6.87) for mycophenolate mofetil (MMF) versus cyclophosphamide (CYC); 2.16 (0.38, 13.36) for tacrolimus (Tac) versus CYC; and 1.25 (0.13, 10.51) for Tac versus MMF. For proteinuric remission the OR was 1.46 (0.81, 3.04) for MMF versus CYC; 1.96 (0.80, 5.11) for Tac versus CYC; and 1.34 (0.43, 3.90) for Tac versus MMF. The probability (95% credible interval) of inducing a creatinine remission at 6 months was Tac 56% (19%, 88%); MMF 51% (23%, 79%); and CYC 37% (28%, 47%). The probability of inducing a proteinuric remission was Tac 41% (23%, 63%); MMF 34% (23%, 50%); CYC 26% (20%, 32%); azathioprine 10% (1%, 55%); prednisone 11% (2%, 38%). None of the results were conclusive when examined in a sensitivity analysis.Conclusion.There is currently insufficient evidence to determine which of these immunosuppressive agents is superior. The probability of renal remission is 50% or lower at 6 months.