bluuebunny/crossref_metadata_2025_split huggingface dataset:
Quantitative Trait Loci Affecting Liver Fat Content in Mice
Authors: Minkina Olga , Cheverud James M , Fawcett Gloria , Semenkovich Clay F , Kenney-Hunt Jane P 
Published: November 2013

Abstract
Nonalcoholic fatty liver disease, a condition in which excess fat accumulates in the liver, is strongly associated with the metabolic syndrome, including obesity and other related conditions. This disease has the potential to progress from steatosis to steatohepatitis, fibrosis, and cirrhosis. The recent increase in the prevalence of the metabolic syndrome is largely driven by changes in diet and activity levels. Individual variation in the response to this obesogenic environment, however, is attributable in part to genetic variation between individuals, but very few mammalian genetic loci have been identified with effects on fat accumulation in the liver. To study the genetic basis for variation in liver fat content in response to dietary fat, liver fat proportion was determined using quantitative magnetic resonance imaging in 478 mice from 16 LG/J X SM/J recombinant inbred strains fed either a high-fat (42% kcal from fat) or low-fat (15% kcal from fat) diet. An analysis of variance confirmed that there is a genetic basis for variation in liver fat content within the population with significant effects of sex and diet. Three quantitative trail loci that contribute to liver fat content also were mapped.
Novel Therapies for Hemodialysis Vascular Access Dysfunction
Authors: Terry Christi M. , Dember Laura M. 
Published: November 2013

Summary
Hemodialysis vascular access dysfunction is a major source of morbidity for patients with ESRD. Development of effective approaches to prevent and treat vascular access failure requires an understanding of the underlying mechanisms, suitable models for preclinical testing, systems for targeted delivery of interventions to maximize efficacy and minimize toxicity, and rigorous clinical trials that use appropriate outcome measures. This article reviews the substantial progress and ongoing challenges in developing novel treatments for arteriovenous vascular access failure and focuses on localized rather than systemic interventions.
Impact of Conversation Map™ Education Tools Versus Regular Care on Diabetes-Related Knowledge of People With Type 2 Diabetes: A Randomized, Controlled Study
Authors: Reaney Matthew , Zorzo Esther Gil , Golay Alain , Hermanns Norbert , Cleall Simon , Petzinger Ute , Koivisto Veikko 
Published: November 2013

Objective. This study compared the effectiveness of Conversation Map™ (CM) education tools versus regular care of adults with type 2 diabetes.
Methods. Participants from Spain and Germany were randomized to either four CM education sessions or regular care. Data were collected at baseline (visit 1), immediately post-education (visit 2), and 6 months later (visit 3). The primary objective was to compare diabetes knowledge between education groups at visit 3, using the Audit of Diabetes Knowledge (ADKnowl) questionnaire (score range 0–100).
Results. Of 681 participants randomized (CM 330, regular care 351), 91.8% completed visit 3. Median ADKnowl scores increased significantly (P &lt; 0.001) in both groups (CM visit 1, 60.3; visit 2, 73.5; and visit 3, 72.5; regular care visit 1, 63.3; visit 2, 73.5; and visit 3, 73.6). At visit 3, scores were not ranked significantly differently between education groups (P = 0.284). In Spain (n = 310), visit 3 scores were ranked higher for CM than for regular care (P &lt; 0.001); in Germany (n = 371), the opposite was true (P &lt; 0.001). Of participants receiving regular care, 78.3% of those in Germany and 13.5% of those in Spain had non-CM structured education between visits 1 and 2. In Spain, CM patients had higher satisfaction with care and goal attainment than regular-care patients at visit 2 (visit 2 P &lt; 0.001, visit 3 P = 0.055). In Germany, CM patients had less emotional distress than regular-care patients (visit 2 P = 0.025, visit 3 P = 0.003). Median A1C decreased similarly in both groups and countries.
Conclusion. Diabetes knowledge and clinical outcomes improved in both education groups. At visit 3, diabetes knowledge in the CM group was not ranked higher than in the regular-care group. In Germany, where regular care frequently involves structured education programs, diabetes knowledge was ranked higher with regular care than with CM. In Spain, where no structured national diabetes education and awareness programs are in place, scores were ranked higher with CM than with regular care.
Statistical Process Control in Automotive Industry
Authors: Korenko Maroš , Kaplik Pavol , Bujna Marian , Pristavka Miroslav 
Published: November 2013

Abstract
Organisations active in the market, regardless of the sphere of action, must constantly face pressures from an uncompromising competition. Therefore, if organisations wish to be successful in the market and constantly move forward, they must draw attention to the quality of products in the market. Statistical process control is the implementation of such statistical methods through which the production process is regulated and controlled to ensure the production of the highest possible amount of products that comply with requirements imposed on them.
Psychometric Properties of 3 Functional Mobility Tests for People With Parkinson Disease
Authors: Verheyden Geert , Kampshoff Caroline S. , Burnett Malcolm E. , Cashell Jessica , Martinelli Louis , Nicholas Alice , Stack Emma L. , Ashburn Ann 
Published: November 2013

BackgroundStandardized outcome measures with high clinical utility are of paramount importance for clinical practice.ObjectiveThe purpose of this study was to examine interrater and intrarater reliability, construct validity, discriminant ability, and smallest detectable differences of the sit-to-stand test (STS), Timed “Up & Go” Test (TUG), and bed mobility test for people with Parkinson disease (PD).DesignA cross-sectional, psychometric evaluation study was conducted.MethodsA group of individuals with PD (PD group) and a group of individuals who were healthy (control group) were recruited through local PD groups and assessed in a movement laboratory in their “on” phase. Measurements of time to perform one STS, TUG, and bed mobility test were collected based on video recordings of that single performance.ResultsThirty-eight individuals with PD (Hoehn and Yahr stages I–IV) and 19 age-matched control participants were recruited. Intraclass correlation coefficients for interrater and intrarater reliability for the PD group ranged from .95 to .99. Bland-Altman plots showed mean differences close to zero and narrow confidence intervals. Construct validity was established by means of moderate to good Spearman rho correlation coefficients with part III of the Unified Parkinson's Disease Rating Scale and the Hoehn and Yahr stage (range=.51–.63). Timings of all tests discriminated participants in the PD group from those in the control group and participants in the PD group in Hoehn and Yahr stages I and II from those in Hoehn and Yahr stages III and IV but did not discriminate “nonfallers” or those with single falls from repeat “fallers” or “nonfreezers” from “freezers.” Applicable smallest detectable differences were established.LimitationsThe results are not generalizable to people in the late stage of PD (Hoehn and Yahr stage IV: n=3).ConclusionsTimings of video recordings of 3 functional mobility tests with high clinical utility showed good psychometric properties for community-dwelling, ambulatory people with PD.
Conservative Treatment of a Proximal Full-Thickness Biceps Brachii Muscle Tear in a Special Operations Soldier
Authors: Helton Matthew S. 
Published: November 2013

BackgroundA transection of the short head of the biceps brachii muscle is an uncommon injury seen among outpatient sports physical therapy clinics. The highest rate of occurrence and the majority of literature that discusses this specific injury are related to US military parachuting. The purpose of this case report is to outline the episode of care from 2 days after the injury through 6 months of conservative treatment, which consisted of therapeutic exercise, manual therapy, and cryotherapy, within an outpatient sports physical therapy clinic in a military setting.Case DescriptionThis case report outlines the initial evaluation, diagnostic imaging, treatment, and 6-month follow-up measures for a 23-year-old male patient who sustained a static line injury resulting in a full-thickness tear of his biceps brachii muscle and a partial tear of the coracobrachialis muscle.OutcomesThe individual described in this case report reported having no functional limitations in regard to his job and leisure activities or any pain at his 6-month follow-up, with a score of 0% noted on his Shortened Disabilities of the Arm, Shoulder, and Hand Questionnaire (QuickDASH). Isokinetic testing revealed a 39.1% decrease in elbow flexion peak torque and a 60.8% decrease in elbow flexion total work output at this same follow-up interval.DiscussionIn determining the appropriate course of treatment for this injury type, conservative physical therapy intervention should be considered as a viable treatment option, as there have been no decisive studies to suggest superior outcomes with other methods such as surgical correction. It is further recommended that research be conducted in an effort to prevent such injuries from occurring, as this mechanism of injury has proven to be much higher among the US military population compared with other military populations.
Prospective review of a single center's general pediatric neurosurgical intraoperative and postoperative complication rates
Authors: van Lindert Erik J. , Delye Hans , Leonardo Jody 
Published: November 2013

Object
The authors conducted a study to compare the complication rate (CR) of pediatric neurosurgical procedures in a general neurosurgery department to the CRs that are reported in the literature and to establish a baseline of CR for further targeted improvement of quality neurosurgical care.

Methods
The authors analyzed the prospectively collected data from a complication registration of 1000 consecutive pediatric neurosurgical procedures in 581 patients from the beginning of the registration in January 2004 through August 2008. A pediatric neurosurgeon was involved in 50.5% of the procedures. All adverse events (AEs) from induction of anesthesia until 30 days postoperatively were recorded.

Results
Overall, 229 complications were counted in 202 procedures. The overall CR was 20.2%, with a 2.7% intraoperative CR and a 17.5% postoperative CR. Tumor surgery was associated with the highest CR (32.7%), followed by CSF disorders (21.8%). The mortality rate was 0.3%. An unplanned return to the operating room in relation to an AE happened in 10.5% of all procedures and in 52% of procedures associated with AEs, the majority of which were related to CSF disorders.

Conclusions
The CR in pediatric neurosurgical procedures was significant, and more than half of the patients with an AE required a repeat surgical procedure. Analysis of CRs should be a prerequisite for the prevention of complications and for the development of targeted interventions to reduce the CR (for example, infection rates).
Unilateral pedicle screw fixation through a tubular retractor via the Wiltse approach compared with conventional bilateral pedicle screw fixation for single-segment degenerative lumbar instability: a prospective randomized study
Authors: Dong Jianwen , Rong Limin , Feng Feng , Liu Bin , Xu Yichun , Wang Qiyou , Chen Ruiqiang , Xie Peigen 
Published: November 2013

Object
Treatment of patients with single-segment degenerative lumbar instability using unilateral pedicle screw fixation can achieve stability and fusion rates similar to those of bilateral pedicle screw fixation. The aim of this study was to analyze the clinical outcome of using unilateral pedicle screw fixation through a tubular retractor via the Wiltse approach to treat single-segment degenerative lumbar instability.

Methods
Thirty-nine consecutive patients with single-segment, low-grade, degenerative lumbar instability were randomly assigned to treatment with either unilateral (n = 20) or bilateral (n = 19) pedicle screw fixation. In the unilateral group, patients underwent unilateral posterior lumbar interbody fusion (PLIF) and ipsilateral pedicle screw fixation through a tubular retractor via the Wiltse approach. In the bilateral group, patients underwent modified bilateral PLIF with bilateral pedicle screw fixation via the posterior midline approach. During follow-up, patients were evaluated using a visual analog scale (VAS), the Japanese Orthopaedic Association (JOA) score, and the Oswestry Disability Index.

Results
The unilateral group had a shorter operative duration (p < 0.05) and less blood loss (p < 0.001). All patients completed more than 2 years of follow-up (mean 36 months). In general, the time trends in improvement on the VAS and JOA differed slightly between the groups through 2 years, but no significant difference in back pain VAS score or leg pain VAS score was found between these 2 groups at the 2-year follow-up. Complete bone fusion was shown on CT in all patients at the 2-year follow-up.

Conclusions
Unilateral pedicle screw fixation through a tubular retractor via the Wiltse approach appears to be as safe and effective as bilateral pedicle screw fixation for the treatment of single-segment degenerative lumbar instability.
Work, Health, Music: The enduring Rusyn model of a good life amid changing socioeconomic contexts of progress
Authors: Cantin K. M. 
Published: November 2013

Rusyns in Eastern and Central Europe have experience with two predominant models of “progress”: the Soviet-style communist and the neoliberal. Proponents of each system promised to better the lives of all but did not take into account what “better” meant to local populations, including Rusyns. Increasingly, European governmental and nongovernmental organizations are redefining notions of progress and development to accord with values of sustainability and a capability approach (CA) to well-being. Giovanola (2005) and Robeyns (2005) have argued that scholars of the CA need to better develop concepts of “personhood” and “human flourishing”, and to better explain the importance of social group membership and norms to living a valued life. The emerging anthropological focus on well-being, emphasizing culturally specific definitions of what happiness and a good life mean, can provide these conceptualizations. As a case in point, I use freelist and interview data obtained from residents in the Prešov Region of Slovakia and the Zakarpattia Oblast of Ukraine along with Rusyn cultural narratives drawn from poems, folktales, plays, songs, interviews, and speeches to identify prevalent models of “personhood” and “a good life”. I discuss how these narratives intersect and diverge with discourses of happiness and progress along with the implications for Rusyns' ability to flourish.
Application of Part-Whole Training Methods to Evaluate When to Introduce NextGen Air Traffic Management Tools to Students
Authors: Vu Kim-Phuong L. , Kiken Ariana , Chiappe Dan , Strybel Thomas Z. , Battiste Vernol 
Published: November 2013

Abstract
The Next Generation Air Transportation System (NextGen) will use advanced technologies and new concepts of operation to accommodate projected increases in air travel over the next few decades. Use of NextGen tools requires air traffic controllers (ATCos) to use different procedures than those required to manage NextGen-unequipped aircraft, and ATCos will need to integrate the 2 skill sets when managing a sector consisting of NextGen-equipped and unequipped aircraft. The goal of the present study was to determine the effectiveness of 2 procedures in the training of student controllers to manage both equipage types. We applied a variant of the part- whole training paradigm in the present study. Using a quasi-experimental design, we trained students from 2 different labs of an internship course to manage air traffic with potential Next- Gen tools concurrent with their traditional training (whole-task group) or after they had time to learn traditional air traffic management skills (part-whole group). Participants were then tested in their ability to manage a simulated sector consisting of different percentages of NextGenequipped and unequipped aircraft at the midterm and after the final week of their internship. Results showed that it is better to train students in manual ATCo skills before introducing Next- Gen tools, unless the students are of higher aptitude. For more skilled students, simultaneously introducing NextGen and manual tools into their curriculum had little negative impact.
A Child’s Garden of Curses: A Gender, Historical, and Age-Related Evaluation of the Taboo Lexicon
Authors: Jay Kristin L. , Jay Timothy B. 
Published: November 2013

Abstract
Child swearing is a largely unexplored topic among language researchers, although assumptions about what children know about taboo language form the basis for language standards in many settings. The purpose of the studies presented here is to provide descriptive data about the emergence of adultlike swearing in children; specifically, we aim to document what words children of different ages know and use. Study 1 presents observational data from adults and children (ages 1-12). Study 2 compares perceptions of the inappropriateness of taboo words between adults and older (ages 9-12) and younger (ages 6-8) children. Collectively these data indicate that by the time children enter school they have the rudiments of adult swearing, although children and adults differ in their assessments of the inappropriateness of mild taboo words. Comparisons of these data with estimates obtained in the 1980s allow us to comment on whether swearing habits are changing over the years. Child swearing data can be applied to contemporary social problems and academic issues.
The process for designing and constructing the Sunpu Kaikan
Authors: Toyokawa Saikaku 
Published: July 2024

AbstractThis study aims to reveal the difficulty of realizing large hyperbolic paraboloid (HP) shell structures comprising reinforced concrete in earthquake‐prone Japan in the 1950s. The analysis focused on the design and construction of Sunpu Kaikan, focusing on the roles of Kenzo Tange and Yoshikatsu Tsuboi, alongside their architectural laboratory staff. It revealed how the experience gained in the Sunpu Kaikan project contributed to two architectural projects in the 1960s: the Niigata City Gymnasium, with its steel‐frame concrete HP shell, and the Yoyogi National Stadium, with its suspension roof structure.
Axonal injury, sleep disturbances, and memory following traumatic brain injury
Authors: Tinney Emma M. , España‐Irla Goretti , Warren Aaron E.L. , Whitehurst Lauren N. , Stillman Alexandra M , Hillman Charles H. , Morris Timothy P. ,   for the Alzheimer's Disease Neuroimaging Initiative
Published: July 2024

AbstractObjectivesTraumatic brain injury (TBI) is associated with sleep deficits, but it is not clear why some report sleep disturbances and others do not. The objective of this study was to assess the associations between axonal injury, sleep, and memory in chronic and acute TBI.MethodsData were acquired from two independent datasets which included 156 older adult veterans (69.8 years) from the Alzheimer's Disease Neuroimaging Initiative (ADNI) with prior moderate‐to‐severe TBIs and 90 (69.2 years) controls and 374 (39.6 years) from Transforming Research and Clinical Knowledge in TBI (TRACK‐TBI) with a recent mild TBI (mTBI) and 87 controls (39.6 years), all who completed an MRI, memory assessment, and sleep questionnaire.ResultsOlder adults with a prior TBI had a significant association between axonal injury and sleep disturbances [β = 9.52, 95% CI (4.1, 14.9), p = 0.01]. Axonal injury predicted changes in memory over 1‐year in TBI [β = −8.72, 95% CI (−18, −2.7), p = 0.03]. We externally validated those findings in TRACK‐TBI where axonal injury within 2 weeks after mTBI was significantly associated with higher sleep disturbances in the TBI group at 2 weeks[β = −7.2, 95% CI (−14, −0.50), p = 0.04], 6 months [β = −16, 95% CI (−24, −7.6), p ≤ 0.01], and 12 months post‐injury [β = −11, 95% CI (−19, −0.85), p = 0.03]. These associations were not significant in controls.InterpretationsAxonal injury, specifically to the left anterior internal capsule is robustly associated with sleep disturbances in multiple TBI populations. Early assessment of axonal injury following mTBI could identify those at risk for persistent sleep disturbances following injury.
Ultra‐Sensitive Bulk Piezophotovoltaic Effect in NaBa(P,Bi) Alloy Under Topological Phase Transition
Authors: Jiang Xiao , Kang Lei , Ye Liangting , Chen Xiaojun , Huang Bing 
Published: July 2024

AbstractThe bulk photovoltaic effect, with ultra‐sensitive control under ambient piezo response, plays a significant role in many modern optoelectronic applications. However, functional bulk photovoltaic materials with high piezo sensitivity are rare, and discovering them is a great challenge. This article proposes a practical design scheme to achieve an ultra‐sensitive bulk piezophotovoltaic effect (BPPVE) in a single‐valley topological alloy material system. The BPPVE is accomplished by reversing the giant shift current in an alloy material that exhibits piezo‐sensitive topological band inversion, as predicted in the acentric single‐valley NaBa(P,Bi) alloy system. First‐principles calculations confirm that the shift current in NaBaP1‐xBix has high directional and magnitude sensitivity (−5000 to 400 µA V−2) in a rather low‐stress region (<0.5 GPa) near the critical alloy concentration (x ∼ 0.48), along with a remarkable topological phase transition. Notably, the stress‐induced bulk photovoltaic effect in NaBa(P,Bi) is much more sensitive than in other existing bulk photovoltaic materials. The outcomes demonstrate an outstanding BPPVE with ultra‐high piezo sensitivity for the first time in topological alloy systems.
Transfer Printing of Photoactive Layer Enabling Efficient, Wearable, and Dual‐Function Organic Solar Cell Modules for a Wireless Healthcare Monitoring System
Authors: Jung Sungwoo , Yang U Jeong , Oh Jiyeon , Jeong Seonghun , Cho Yongjoon , Lee Gwang Heon , Choi Moon Kee , Yang Changduk 
Published: July 2024

AbstractWhile transfer‐printing is a great technique for efficient film fabrication of many emerging devices on various substrates, its application in organic solar cells (OSCs) is rarely explored. Besides, it is highly challenging to fabricate a large‐scale production of a “dual‐function OSC module” that runs two‐objective functions simultaneously in a given single system. Through comprehensive investigation on the transfer‐printing feasibility of various π‐conjugated organic materials, in addition to successful transfer‐printed OSC and flexible OSC module, implementation of dual‐function OSC modules via the transfer‐printing, in which two individual sub‐cell series based on dual‐purpose photoactive layers are separately integrated into a single system is showcased here. Moreover, the fabrication and operation of a wearable integrated self‐powered system for wireless healthcare monitoring with the wearable transfer‐printed dual‐function OSC module are also demonstrated. This study opens the door to fabricating OSCs with multi‐objective structures via the transfer‐printing technique, which enables the extra device‐level values for advanced energy‐related applications.