bluuebunny/crossref_metadata_2025_split huggingface dataset:
Asymmetric impact of Atlantic Multidecadal Oscillation on El Niño and La Niña characteristics
Authors: Sung Mi‐Kyung , An Soon‐Il , Kim Baek‐Min , Kug Jong‐Seong 
Published: June 2015

AbstractThe long‐lasting cold surface conditions of North Atlantic, i.e., the negative phase of Atlantic Multidecadal Oscillation (AMO), can intensify the El Niño–Southern Oscillation through the enhanced air‐sea coupling under the increased central‐to‐eastern tropical Pacific mean sea surface temperature. However, the impact of warmer mean sea surface temperature (SST) is more efficient in the intensifying El Niño than La Niña, because of the nature of the exponential growth of atmospheric convection to SST change. Moreover, the farther eastward shift of the atmospheric convection during the negative AMO leads to the stronger El Niño due to the longer delayed negative feedback by oceanic waves. Therefore, the AMO mainly influences the El Niño intensity rather than La Niña intensity.
Microcrystalline cellulose as reactive reinforcing fillers for epoxidized soybean oil polymer composites
Authors: He Ming , Zhou Jianjun , Zhang Huan , Luo Zhenyang , Yao Jianfeng 
Published: June 2015

ABSTRACTMicrocrystalline cellulose (MCC) and its oxidized product dialdehyde cellulose (DAC) were introduced as the reinforcing filler in epoxidized soybean oil (ESO) thermosetting polymer. The composites comprising up to 25 wt % cellulose fillers were obtained via a solution casting. The reinforcing effects of the cellulose were evaluated by microstructure analysis, dynamic mechanical analysis, and tensile and thermal stability tests. The results showed that at the same filler concentration, DAC led to higher stretching strength, modulus, and break elongation than MCC. The 5 wt % DAC loading in ESO polymer exhibits the highest toughness and thermal stability due to the good dispersion and interfacial interaction between DAC and ESO polymer matrix. The increased storage modulus and glass transition temperature also indicate the cellulose fillers impart stiffness to the composites. © 2015 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2015, 132, 42488.
Role of dual dopants in highly ordered crystalline polyaniline nanospheres: Electrode materials in supercapacitors
Authors: Boddula Rajender , Srinivasan Palaniappan 
Published: June 2015

ABSTRACTAniline is oxidized by ammonium persulfate oxidant with a weak organic acid, 1,3‐(6,7)‐napthalene trisulfonic acid (NTSA), via an aqueous polymerization pathway to polyaniline (PANI) salt. The effects of the sodium lauryl sulfate surfactant, mineral acid [sulfuric acid (H2SO4)], and a combination of surfactant with mineral acid in the aniline polymerization reaction are also carried. These salts were designated as PANI–NTSA–dodecyl hydrogen sulfate (DHS), PANI–NTSA–H2SO4, and PANI–NTSA–DHS–H2SO4, respectively. Interestingly, PANI–NTSA–DHS showed a highly ordered crystalline sample with a nanosphere morphology. These PANIs were used as electrode materials in supercapacitor applications. Among the four salts, the PANI–NTSA–DHS–H2SO4 material showed higher values of specific capacitance (520 F/g), energy (26 W h/kg), and power densities (200 W/kg) at 0.3 A/g. Moreover, 77% of the original capacitance was retained after 2000 galvanostatic charge–discharge cycles with a Coulombic efficiency of 98–100%. PANI–NTSA–DHS–H2SO4 was obtained in excellent yield with an excellent conductivity (6.8 S/cm) and a thermal stability up to 235°C. © 2015 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2015, 132, 42510.
Bioconjugation of Serum Albumin to a Maleimide‐appended Porphyrin/Cyclodextrin Supramolecular Complex as an Artificial Oxygen Carrier in the Bloodstream
Authors: Kitagishi Hiroaki , Kawasaki Hiroki , Kano Koji 
Published: June 2015

AbstractHemoCD is an inclusion complex of per‐O‐methylated β‐cyclodextrin dimer and an iron(II) porphyrin, which forms a stable O2complex in water. Therefore, hemoCD has the potential for use as a synthetic O2carrier in mammalian blood. In this study, a hemoCD derivative having a maleimide group (Mal‐hemoCD) was conjugated to a Cys residue of serum albumin via a Michael addition reaction in order to increase the circulation time of the O2carrier. The O2‐binding affinities (P1/2[Torr]) and half‐lives (t1/2[h]) of the O2adducts at pH 7.4 and 25 °C were determined to be 9 Torr and 23 h for Mal‐hemoCD, and 10 Torr and 14 h for albumin‐conjugated hemoCD (Alb‐hemoCD). Our pharmacokinetic study revealed that renal excretion of Alb‐hemoCD was effectively suppressed and that half of injected Alb‐hemoCD remained in blood at 3 h after injection. It is noteworthy that Mal‐hemoCD also had a long circulation time because of the bioconjugation reaction that occurred during circulation in the bloodstream.
Identification of AⅡ amacrine, displaced amacrine, and bistratified ganglion cell types in human retina with antibodies against calretinin
Authors: Lee Sammy C.S. , Weltzien Felix , Madigan Michele C. , Martin Paul R. , Grünert Ulrike 
Published: June 2015

ABSTRACTAntibodies against calretinin are markers for one type of rod pathway interneuron (AⅡ amacrine cell) in the retina of some but not all mammalian species. The AⅡ cells play a crucial role in night‐time (scotopic) vision and have been proposed as a target for optogenetic restoration of vision in retinal disease. In the present study we aimed to characterize the AⅡ cells in human retina. Postmortem human donor eyes were obtained with ethical approval and processed for calretinin immunofluorescence. Calretinin‐positive somas in the inner nuclear and the ganglion cell layer were filled with the lipophilic dye DiI. The large majority (over 80%) of calretinin‐immunoreactive cells is located in the inner nuclear layer, is immunopositive for glycine transporter 1, and shows the typical morphology of AⅡ amacrine cells. In addition, a small proportion of calretinin‐positive cells in the inner nuclear layer and in the ganglion cell layer is glutamic acid decarboxylase‐positive and shows the morphology of widefield amacrine cells (stellate, semilunar, and thorny amacrine cells). About half of the calretinin cells in the ganglion cell layer are bistratified ganglion cells resembling the small bistratified (presumed blue‐ON/yellow‐OFF) and the G17 ganglion cell previously described in primates. We conclude that in human retina, antibodies against calretinin can be used to identify AⅡ amacrine cells in the inner nuclear layer as well as widefield amacrine and small bistratified ganglion cells in the ganglion cell layer. J. Comp. Neurol. 524:39–53, 2016. © 2015 Wiley Periodicals, Inc.
Analysis and improvement of a fair remote retrieval protocol for private medical records
Authors: Deng Jiang , Xu Chunxiang , Wu Huai , Chen Jie 
Published: June 2015

SummaryCloud computing, as a new‐generation IT architecture, offers an applicable approach for the medical storage and exchange in electronic health networks. However, it also brings the security and privacy concerns because patients lost physical control of their health information. Therefore, it is critical to maintain fairly retrievable to the private medical records over suspicious cloud servers. Wang proposed a fair remote retrieval (FRR) model to enable an independent third party to secure that it is integrated and retrievable to outsource private medical records. One distinctive feature of FRR is to support and address the medical tangle between hospitals and patients, and employ a committee to recover the necessary original data. Unfortunately, FRR cannot ensure the integrity of the remote medical records as claimed. Specifically, a malicious cloud server could cheat the verifier that its medical information were well‐maintained. But in fact, it only holds the hash values of the original data. Moreover, it can generate a valid but malicious response without being detected by the verifier, and all the medical records are discarded with the help of tag queries. Finally, we present an improved protocol named an improved fair remote retrieval protocol (IFR)2 to fix the security minor faults with preserving all the properties of FRR. Copyright © 2015 John Wiley & Sons, Ltd.
Self‐stigma of seeking treatment and being male predict an increased likelihood of having an undiagnosed eating disorder
Authors: Griffiths Scott , Mond Jonathan M. , Li Zhicheng , Gunatilake Sanduni , Murray Stuart B. , Sheffield Jeanie , Touyz Stephen 
Published: June 2015

ABSTRACTObjectiveTo examine whether self‐stigma of seeking psychological help and being male would be associated with an increased likelihood of having an undiagnosed eating disorder.MethodA multi‐national sample of 360 individuals with diagnosed eating disorders and 125 individuals with undiagnosed eating disorders were recruited. Logistic regression was used to identify variables affecting the likelihood of having an undiagnosed eating disorder, including sex, self‐stigma of seeking psychological help, and perceived stigma of having a mental illness, controlling for a broad range of covariates.ResultsBeing male and reporting greater self‐stigma of seeking psychological help was independently associated with an increased likelihood of being undiagnosed. Further, the association between self‐stigma of seeking psychological help and increased likelihood of being undiagnosed was significantly stronger for males than for females.DiscussionPerceived stigma associated with help‐seeking may be a salient barrier to treatment for eating disorders—particularly among male sufferers. © 2015 Wiley Periodicals, Inc (Int J Eat Disord 2015; 48:775–778)
Temporal dynamics of seed excretion by wild ungulates: implications for plant dispersal
Authors: Picard Mélanie , Papaïx Julien , Gosselin Frédéric , Picot Denis , Bideau Eric , Baltzinger Christophe 
Published: June 2015

AbstractDispersal is a key process in metapopulation dynamics as it conditions species' spatial responses to gradients of abiotic and biotic conditions and triggers individual and gene flows. In the numerous plants that are dispersed through seed consumption by herbivores (endozoochory), the distance and effectiveness of dispersal is determined by the combined effects of seed retention time in the vector's digestive system, the spatial extent of its movements, and the ability of the seeds to germinate once released. Estimating these three parameters from experimental data is therefore crucial to calibrate mechanistic metacommunity models of plant–herbivore interactions. In this study, we jointly estimated the retention time and germination probability of six herbaceous plants transported by roe deer (Capreolus capreolus), red deer (Cervus elaphus), and wild boar (Sus scrofa) through feeding experiments and a Bayesian dynamic model. Retention time was longer in the nonruminant wild boar (>36 h) than in the two ruminant species (roe deer: 18–36 h, red deer: 3–36 h). In the two ruminants, but not in wild boar, small and round seeds were excreted faster than large ones. Low germination probabilities of the excreted seeds reflected the high cost imposed by endozoochory on plant survival. Trait‐mediated variations in retention time and germination probability among animal and plant species may impact plant dispersal distances and interact with biotic and abiotic conditions at the release site to shape the spatial patterns of dispersed plant species.
A novel way to understand plant species preferences in relation to groundwater discharge conditions using a trait‐based approach
Authors: van der Knaap Yasmijn A. M. , Douma Jacob C. , Aerts Rien , van Ek Remco , van Bodegom Peter M. 
Published: June 2015

AbstractGroundwater discharge sites harbour characteristic and often rare plant communities that differ substantially from groundwater recharge sites. It is not known which abiotic conditions at these sites drive the differences in community composition. A trait‐based approach, which relates species traits to abiotic conditions, may provide insight in this relationship and improve conservation management of these characteristic communities. We used this approach to identify the following: (i) dominant abiotic conditions that shape plant communities at discharge sites and (ii) characteristic traits associated with these abiotic conditions. First, we performed a (qualitative) literature survey to relate plant traits to various abiotic conditions at discharge sites. Second, we performed a meta‐analysis to quantitatively test the trait selection at discharge sites. For the meta‐analysis, we compiled a species discharge preference database (n = 170), based on literature and field data. We performed linear regression to relate traits to species discharge preference. Only 5 out of the 11 traits tested (low leaf phosphorus content, high leaf N:P, low rate of clonal reproduction, low maximum height and high seed mass) were significantly related to discharge preference, while the explained variance was low (R2 < 0.09). Our results suggest the following: (i) Despite the inclusion of traits specifically related to prevailing local environmental conditions, beyond commonly applied traits, hardly any differences were revealed; this indicates a need for more comprehensive eco‐physiological understanding (and information on the selection of combinations of traits). (ii) A trait‐based approach may not be highly distinctive in environments differing in only a few specific characteristics. Copyright © 2015 John Wiley & Sons, Ltd.
Resveratrol ameliorates chronic high altitude exposure‐induced oxidative stress and suppresses lipid metabolism alteration in rats
Authors: Xu Chunlan , Qiao Xiangjin , Zhao Yanfei , Sun Rui , Shang Xiaoya , Niu Weining 
Published: June 2015

High altitude affects energy metabolism. Resveratrol is the natural compound that activates sirtuins, which produce beneficial effects on lipid metabolism. The study was conducted to investigate the role of resveratrol in lipid metabolism of rats exposed to a high altitude hypoxia environment. Sprague–Dawley rats were divided into control, resveratrol (30 mg/kg B.W./d) (Res), high altitude hypoxia (HH), and high altitude hypoxia + resveratrol (30 mg/kg B.W./d) (HH+Res) groups. Rats in HH and HH+Res groups were placed in a hypobaric chamber at a stimulated elevation of 4500 m for 30 days. Plasma lipid profile, antioxidant indexes, key enzyme activities, lipid metabolism‐related genes, and hypoxia‐inducible factors (HIFs) expression were evaluated. Results showed that resveratrol alleviated hypobaric hypoxia‐induced enlargement of lung and spleen, and decreased serum malondialdehyde (MDA), plasma high density lipoprotein (HDL) and cholesterol (CHOL) contents, increased liver superoxide dismutase (SOD) activity and Sirtuin 1 (Sirt‐1) expression levels, and decreased liver MDA and triglyceride (TG) levels compared to the HH group. Moreover, resveratrol increased fat hormone sensitive lipase (HSL) activity, and suppressed fat Acetyl‐CoA carboxylase (ACC), Carnitine palmitoyltransferase (CPT‐I) and fatty acid synthetase (FAS) activity. In addition, resveratrol decreased liver CCAAT/enhancer binding protein alpha (C/EBPα), peroxisome proliferator‐activated receptor γ (PPARγ), and hypoxia inducible factor‐1 alpha and hypoxia inducible factor‐2 alpha (HIF‐1α and HIF‐2α) expression levels compared to the HH group. In conclusion, resveratrol can effectively ameliorate high altitude hypoxia‐induced oxidative stress and alteration of lipid metabolism, which is associated with the HIF signaling pathway.Practical applications: Resveratrol may be a feasible agent for ameliorating high altitude‐induced oxidative stress and lipid metabolism dysfunction. Moreover, the HIF‐mediated alterations in genes involved in fat metabolism (Srit1, C/EBPα, and PPARγ) may be targets to prevent and treat lipid metabolic disease under a high altitude hypoxia environment.Resveratrol can effectively ameliorate high altitude hypoxia‐induced oxidative stress and alteration on lipid metabolism. Moreover, the HIFs‐mediated alterations in genes involved in fat metabolism (Srit1, C/EBPα and PPARγ) may be targets to prevent and treat lipid metabolic disease under high altitude hypoxia environment.
Tectonics, sedimentation and surface processes: from the erosional engine to basin deposition
Authors: Castelltort Sébastien , Whittaker Alex , Vergés Jaume 
Published: June 2015

AbstractThis special issue collects a number of papers mainly reflecting discussions during the ‘tectonics, sedimentation and surface processes’ sessions (TSSP) organized at recent EGU conferences (2012, 2013, 2014), as well as related studies that have appeared in Earth Surface Processes and Landforms over the last two years. The sedimentary record has long been used to invert for deformation at all scales and in all tectonics settings. Growth strata, sediment provenance, sequence stratigraphy and changing depositional environments have all provided first‐order constraints on quantifying deformation at a range of spatial and temporal scales. At the same time, these studies have motivated much work on the influence of tectonics on both sedimentation patterns and basin fill successions. However, relatively few studies have considered the whole integrated system of catchment erosion, fluvial transport and sediment deposition together, often concentrating on either the basin or the catchment separately. Recently however, methodological progress in quantifying rates of surface processes in the upstream erosion and transfer zones, as well as revived interest in the couplings between surface processes, tectonics and climate, have made it possible to renew our understanding of the interactions between sedimentation and tectonics within the framework of the whole integrated sediment routing system. Although the studies within this special issue are only a fraction of the work presented over the last five years of the TSSP sessions, the manuscripts presented here reflect a selection of the broad content and diversity of studies that integrate both sedimentation and surface processes to understand deformation in the context of sedimentary systems. They highlight and are organized into three active challenges of the field: (1) tectonics and climate into landscapes; (2) signal propagation within sediment routing systems; and (3) modeling of tectonic and surface processes. Copyright © 2015 John Wiley & Sons, Ltd.
In‐Silico Template Selection of In‐Vitro Evolved Kalata B1 of Oldenlandia Affinis for Scaffolding Peptide‐Based Drug Design
Authors: Senthilkumar B. , Kumar Prakash , Rajasekaran R. 
Published: June 2015

ABSTRACTStructural stability of Oldenlandia affinis cyclotide, kalata B1 of native (1NB1) and two mutants 2F2I ([P20D, V21K] kB1) and 2F2J ([W19K, P20N, V21K] kB1) was investigated. Single model analysis showed high number of intra‐molecular interactions followed by more proportion of beta sheet contents in [P20D, V21K] kB1 as compared to that of native and the other mutant of kalata B1. Further, the modern conformational sampling approach, an alternate to classical molecular dynamics was introduced, which revealed that the [P20D, V21K] kB1 was identified as structurally stable one, substantiated by various structural events viz., root mean square deviation, root mean square fluctuation, and angular deviation by Ramachandran plot. Moreover, the statistically validated contours of polar surface area, hydrogen bond distribution and the distance of disulfide bridges also supported the priority of [P20D, V21K] kB1 with respect to stability. From this work, it is proposed that the [P20D, V21K] kB1 (2F2I) could be the best template for scaffolding peptide based drug design. J. Cell. Biochem. 117: 66–73, 2016. © 2015 Wiley Periodicals, Inc.
Analysis of functional outcomes in patients with mandible reconstruction using vascularized fibular grafts
Authors: Sakuraba Minoru , Miyamoto Shimpei , Fujiki Masahide , Higashino Takuya , Oshima Azusa , Hayashi Ryuichi 
Published: June 2015

BackgroundsAlthough a vascularized fibular graft (VFG) is the favored method for mandible reconstruction, only few functional reports have been published. In this study, surgical outcomes and functional results after mandible reconstruction were analyzed.Patients and methodsFrom 1999 through 2010, oromandibular defects after segmental mandibulectomy were reconstructed with VFG in 101 patients. Operative outcomes and subjective functional evaluation was performed. Of these, 44 patients could be evaluated for functional outcomes, and bite force was measured with an occlusal force meter in 24 patients.ResultsMajor surgical complications required secondary revisional surgery developed in four patients. A normal diet was possible in 37 patients (84.1%), and a soft diet was possible in 7 patients (15.9%). Conversational ability was rated as excellent in 42 patients (95.5%). The mean bite force on the nonaffected side of the mandible was 187.7 N, and bite force decreased as the number of osteotomies in the VFG increased. Furthermore, bite force was significantly lower (P = 0.001) on the affected side (58.2 N), compared to nonaffected side (191.9 N).ConclusionsAlthough masticatory force decreases as the number of osteotomies increases, oral function after mandible reconstruction is satisfactory in most cases. Transfer of a VFG is a safe and reliable method for functional mandible reconstruction. © 2015 Wiley Periodicals, Inc. Microsurgery 37:101–104, 2017.
Accession and association: The effects of European integration and neoliberalism on rising inequality and kin‐neighbor reciprocity in the Republic of Macedonia
Authors: Otten Justin M. 
Published: June 2015

AbstractSince the dissolution of socialist Yugoslavia more than twenty years ago, there has been a monumental shift in economic policy and governance in the Republic of Macedonia. Though political rhetoric claims that markets are regulated by the state, the implementation of neoliberal policies has resulted in private interests taking control of industries that were formerly socially owned and managed. This process has led to significant inequality in the country, from disparities in wealth and opportunities to unemployment and poverty. In its largest wine region, Tikveš, one finds evidence of the crossroads where habits of global consumption meet rural kinship structures in a unique geographical and political setting. As the country is seeking greater integration with the Euro–American alliance, the Macedonian case enables us to think about reciprocity and hospitality in terms of external, global impositions. However, it also shows resilience to such forces, where cultural traditions and customs (such as hospitality and reciprocity) not only remain but have been strengthened.