bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Efficient Synthesis of 1,2‐Bis(alkoxycarbonyl)pyrazol‐3‐ones from 2,3‐Allenoic Acids, Azodicarboxylates and PPh3.
Authors: Lue Ruizhi , Cheng Xin , Zheng Xingliang , Ma Shengming 
Published: April 2014

AbstractThe structure of the product (IIIf) is confirmed by X‐ray analysis.
ChemInform Abstract: Efficient Iodine‐Catalyzed One Pot Synthesis of Highly Functionalized Pyrazoles in Water.
Authors: Srivastava Madhulika , Rai Pratibha , Singh Jaya , Singh Jagdamba 
Published: April 2014

AbstractThe reaction proceeds in water with I2 as a catalyst without any by‐product formation and the isolation of the product does not require a column chromatography.
ChemInform Abstract: 1,4‐Dialkyl‐1,4‐diazabutadienes: Their Reactions with Aluminum and Indium Halides.
Authors: Rojas‐Saenz Hector , Suarez‐Moreno Galdina V. , Ramos‐Garcia Iris , Duarte‐Hernandez Angelica M. , Mijangos Edgar , Pena‐Hueso Adrian , Contreras Rosalinda , Flores‐Parra Angelina 
Published: April 2014

AbstractDiazabutadiene react with aluminum halides in toluene to furnish ionic aluminum coordination compounds [cf.
ChemInform Abstract: Synthesis of 2‐Methyl‐1‐[(5‐methylfuran‐2‐yl)methyl]‐ and 2‐Methyl‐1‐[(5‐methylpyrrol‐2‐yl)methyl]‐1H‐benzimidazoles.
Authors: Stroganova T. A. , Red'kin V. M. , Kovalenko G. A. , Vasilin V. K. , Krapivin G. D. 
Published: April 2014

AbstractA straightforward route for the synthesis of the title furanylmethylbenzimidazoles (V) via cyclization of vicinal aminoanilides (IV) and its transformation into related pyrrolylmethylbenzimdazoles using a Paal—Knorr cyclization are described.
ChemInform Abstract: Activated Alumina Ball Catalyzed Expeditious Synthesis of 2‐Alkylbenzimidazoles with Special Emphasis on Susceptible Side Chains Possessing Amide Functionality.
Authors: Ghosh Sabari , Hudrlik Anne , Mukhopadhyay Chhanda 
Published: April 2014

AbstractA green protocol for the solvent‐free synthesis of 2‐alkylbenzimidazoles under neutral conditions via alumina ball‐catalyzed condensation of o‐phenylenediamines with carboxylic acids is developed.
ChemInform Abstract: Palladium‐Catalyzed Decarboxylative C‐H Alkynylation of Benzoxazoles with α,β‐Ynoic Acids.
Authors: Kim Jinsik , Kang Dongjin , Yoo Eun Jeong , Lee Phil Ho 
Published: April 2014

AbstractHeterocycles like imidazoles or thiazoles do not react under the present conditions.
ChemInform Abstract: Conjugated Nitroalkenes in Cycloaddition Reactions. Part 18. Regio‐ and Stereoselectivity of [2 + 3] Cycloaddition Reactions Between gem‐Chloronitroethene and (Z)‐C,N‐Diarylnitrones.
Authors: Jasinski R. , Mikulska M. , Koifman O. , Baranski A. 
Published: April 2014

AbstractThe title reaction leads to a stereoisomeric mixture of 3,4‐cis and 3,4‐trans‐2,3‐diaryl‐4‐chloro‐4‐nitroisoxazolidines (III)/(IV) with predominance of the cis‐isomer.
ChemInform Abstract: Copper‐Mediated Sequential C—N and N—N Bond Formation: Facile Synthesis of Symmetrical 1,2,4‐Triazoles.
Authors: Li Zhonglian , Zhang Zhiguo , Zhang Wei , Liu Qingfeng , Liu Tongxin , Zhang Guisheng 
Published: April 2014

AbstractA convenient method for the dimerization of aromatic amidines to provide symmetrical triazoles is developed by using low‐toxic, stable, readily available, and inexpensive amidine hydrochlorides.
ChemInform Abstract: C—S Coupling Using a Mixed‐Ligand Pd Catalyst: A Highly Effective Strategy for Synthesizing Arylthio‐Substituted Heterocycles.
Authors: Cong Mei , Fan Yuting , Raimundo Jean‐Manuel , Xia Yi , Liu Yang , Quelever Gilles , Qu Fanqi , Peng Ling 
Published: April 2014

AbstractFor the first time a mixed‐ligand system, which can also activate C—Cl bonds in heteroaryl rings for C—S bond formation, is used in the title reaction.
ChemInform Abstract: Synthesis and Antioxidant Activity of Bis and Tris Heterocycles.
Authors: Mahaboob Basha Nabhubygari , Seenaiah Dandu , Padmaja Adivireddy , Padmavathi Venkatapuram , Bhargav Desaraju Suresh , Vijaya Tartte 
Published: April 2014

AbstractNew compound (IIIa) displays radical scavenging activity in all the three tested methods greater than the standard ascorbic acid, and compounds (Va) and (VIIIa) show activities equal to the standard ascorbic acid.
ChemInform Abstract: Enantioselective N‐Heterocyclic Carbene Catalyzed Annulation Reactions with Imidazolidinones.
Authors: McCusker Elizabeth O'Bryan , Scheidt Karl A. 
Published: April 2014

AbstractThis highly selective carbene catalyzed reaction gives various differently substituted bicyclic lactones through a formal [4 + 2] annulation reaction.
ChemInform Abstract: A New Bis‐Fused π‐Electron Donor Composed of Tetrathiafulvalene and 2‐(Xanthen‐9‐ylidene)‐1,3‐dithiole.
Authors: Kato Minami , Shirahata Takashi , Misaki Yohji 
Published: April 2014

Abstract4 Title compounds of type (III) are prepared.
ChemInform Abstract: An Efficient Green Multi‐Component Reaction Strategy for the Synthesis of Highly Functionalized Pyridines and Evaluation of Their Antibacterial Activities.
Authors: Srinivasula Reddy Lakkireddy , Ram Reddy Tirumalareddy , Mohan Reddy Bodireddy , Mahesh Avula , Lingappa Yeramanchi , Gangi Reddy Nallagondu Chinna 
Published: April 2014

Abstract9 Title compounds of type (IV) are prepared by grinding the reaction components together with K2CO3 at room temperature and their antibacterial activities are screened.
ChemInform Abstract: A Study on the Selectivity of Arylzinc Reagents in Cross‐Coupling Reactions with Chemically Equivalent and Pseudo‐Equivalent Dibromopyridines.
Authors: Jung Hye‐Soo , Kim Seung‐Hoi 
Published: April 2014

AbstractSite‐selective coupling reactions of aryl‐ and heteroarylzinc compounds with both chemically equivalent and pseudo‐equivalent carbon‐bromine compounds are investigated.
ChemInform Abstract: Rapid and Selective in situ Reduction of Pyridine‐N‐oxides with Tetrahydroxydiboron.
Authors: Londregan Allyn T. , Piotrowski David W. , Xiao Jun 
Published: April 2014

AbstractFunctionalization of pyridine‐N‐oxides and subsequent reduction provides 2‐substituted pyridines.
ChemInform Abstract: Iron‐Catalyzed Three‐Component Tandem Process: A Novel and Convenient Synthetic Route to Quinoline‐2,4‐Dicarboxylates from Arylamines, Glyoxylic Esters, and α‐Ketoesters.
Authors: Wei Wei , Wen Jiangwei , Yang Daoshan , Sun Xuejun , You Jinmao , Suo Yourui , Wang Hua 
Published: April 2014

AbstractThe new multicomponent reaction of aromatic amines, glyoxylic esters, and α‐ketoesters provides an attractive approach to a series of functionalized quinoline derivatives with promising unique pharmaceutical, biological, and fluorescence‐labeling applications.
ChemInform Abstract: Synthesis and Antimicrobial Activity of Pyrazolinone and Pyrazole Analogues Containing Quinoline Moiety.
Authors: Amir Mohd , Javed Sadique A. , Hassan Mohd Zaheen 
Published: April 2014

AbstractNew compound (IIId) is the most potent antimicrobial agent of the series showing broad spectrum antimicrobial activities.
ChemInform Abstract: Catalytic Enantioselective Synthesis of Functionalized Tropanes Reveals Novel Inhibitors of Hedgehog Signaling.
Authors: Narayan Rishikesh , Bauer Jonathan O. , Strohmann Carsten , Antonchick Andrey P. , Waldmann Herbert 
Published: April 2014

AbstractA highly stereoselective [3 + 2] cycloaddition of fused azomethine ylides and nitroalkanes using a Cu(I)‐catalyst and (Rpl)‐FeSulPhos as chiral ligand is described.
ChemInform Abstract: Broensted Acidic Ionic Liquid Based Magnetic Nanoparticles: A New Promoter for the Biginelli Synthesis of 3,4‐Dihydropyrimidin‐2(1H)‐ones/thiones.
Authors: Safari Javad , Zarnegar Zohre 
Published: April 2014

AbstractA Broensted acidic ionic liquid imidazolium hydrogen sulfate immobilized on magnetic Fe3O4 nanoparticles exhibits excellent catalytic activity in the Biginelli‐type synthesis of a diverse range of pyrimidine derivatives (IV).
ChemInform Abstract: Synthesis, Antiproliferative and Apoptosis‐Inducing Activity of Thiazolo[5,4‐d]pyrimidines.
Authors: Singh Baljinder , Guru Santosh K. , Kour Smit , Jain Shreyans K. , Sharma Rajni , Sharma Parduman R. , Singh Shashank K. , Bhushan Shashi , Bharate Sandip B. , Vishwakarma Ram A. 
Published: April 2014

Abstract14 Title compounds of type (V) are prepared and tested for their antiproliferative and apoptosis‐inducing activities.
ChemInform Abstract: Synthesis of Pyrazolo[3,4‐d]‐4,5‐dihydropyrimidines Through [5 + 1] Cyclocondensation.
Authors: Ryabukhin Sergey V. , Granat Dmitry S. , Plaskon Andrey S. , Volochnyuk Dmitriy M. , Shivanyuk Alexander N. 
Published: April 2014

AbstractMore than twenty pyrazolodihydropyrimidine derivatives are prepared through condensation of secondary amidines with aromatic aldehydes in the presence of TmsCl as activator for the CO‐group and water scavenger.
ChemInform Abstract: New Method of Synthesis of 3,5,6,7‐Tetrahydro[1,2,4]triazolo[1,5‐a]pyrimidine‐2(1H)‐thione (VII)
Authors: Fizer M. M. , Slivka M. V. , Lendel V. G. 
Published: April 2014

Abstractvia electrophilic heterocyclization of 5‐allylaminotriazole derivative (IV)
ChemInform Abstract: Reaction of 3‐Alkynylquinoxaline‐2‐carbonitriles with Sodium Azide: An Experimental and Theoretical Study.
Authors: Tyaglivy A. S. , Steglenko D. V. , Gulevskaya A. V. 
Published: April 2014

AbstractReaction of the title carbonitriles (I) with NaN3 in hot DMF results in the formation of substituted 2H‐1,2,3‐triazoles (II).
ChemInform Abstract: The [4 + 2] Cycloaddition of Donor—Acceptor Cyclobutanes and Nitrosoarenes.
Authors: Vemula Naresh , Stevens Andrew C. , Schon Tyler B. , Pagenkopf Brian L. 
Published: April 2014

AbstractThe Yb(OTf)3‐catalyzed [4+2]‐cycloaddition of the investigated cyclobutane derivative and nitrosoarenes proceeds regioselectively if no strongly electron withdrawing group (a regioisomer is formed) and no strongly electron donating group (no reaction) is present in the nitrosoarene.
ChemInform Abstract: Triazino Indole—Quinoline Hybrid: A Novel Approach to Antileishmanial Agents.
Authors: Sharma Rashmi , Pandey Anand Kumar , Shivahare Rahul , Srivastava Khushboo , Gupta Suman , Chauhan Prem M. S. 
Published: April 2014

AbstractMost of the synthesized title compounds (III) (19 examples) are found to be active against intracellular amastigote form of Leishmania donovani.
ChemInform Abstract: 2,2‐Bis(trifluoromethyl)‐2,3‐dihydro‐1H‐1,5‐benzodiazepines
Authors: Petko K. I. , Vorobey V. M. , Gutov A. V. , Chernega A. N. 
Published: April 2014

Abstractsynthesis via cyclization of hexafluoroacetone N‐phenylimine derivatives (V)
ChemInform Abstract: Synthesis of 4‐Amino‐substituted Tetrahydropyrimido[4,5‐d]azocines.
Authors: Voskressensky L. G. , Ovcharov M. V. , Borisova T. N. , Listratova A. V. , Kulikova L. N. , Sorokina E. A. , Gromov S. P. , Varlamov A. V. 
Published: April 2014

AbstractThe synthesis of the title compounds (VII) involves the transformation of pyrimidines (I) into 4‐oxotetrahydropyrimidoazocines via reaction with alkynes and subsequent transformations of the 4‐oxopyrimidine fragment.
ChemInform Abstract: A Traceless Directing Group for C—H Borylation.
Authors: Preshlock Sean M. , Plattner Donald L. , Maligres Peter E. , Krska Shane W. , Maleczka Robert E. Jr. , Smith Milton R. III 
Published: April 2014

AbstractA strategy is described for the regioselective substitution of a variety of N‐unsubstituted N‐heterocycles with HBpin.
ChemInform Abstract: Design, Synthesis, Antiviral, and Cytostatic Evaluation of Novel Isoxazolidine Analogues of C‐Nucleotides.
Authors: Grabkowska‐Druzyc Magdalena , Balzarini Jan , Piotrowska Dorota G. 
Published: April 2014

AbstractA series of novel isoxazolidines (III) (25 examples), are prepared by a catalyst‐free 1,3‐dipolar cycloaddition reaction of nitrones (I) with styrenes (II).
ChemInform Abstract: Eudesmanolides and Guaianolides from Carpesium triste
Authors: Wu Hai‐Bo , Wang Wen‐Shu , Liu Ting‐Ting , Jiao Yu‐Guo 
Published: April 2014

Abstractisolation and structure of new eudesmanolide (I) and guaianolides (II),(III)
ChemInform Abstract: New Dammarane‐Type Saponins from the Roots of Panax notoginseng
Authors: Qiu Li , Jiao Yang , Huang Gui‐Kun , Xie Ji‐Zhao , Miao Jian‐Hua , Yao Xin‐Sheng 
Published: April 2014

Abstractisolation and structure elucidation
ChemInform Abstract: A Diversity Oriented One‐Pot Synthesis of Novel Iminosugar C‐Glycosides.
Authors: Senthilkumar Soundararasu , Prasad Sure Siva , Kumar Ponminor Senthil , Baskaran Sundarababu 
Published: April 2014

AbstractThe reaction proceeds with complete regio‐ and stereoselectivity.
ChemInform Abstract: Chemoenzymatic Synthesis of 3′‐Deoxy‐3′‐(4‐substituted‐triazol‐1‐yl)‐5‐methyluridine.
Authors: Arya Anu , Mathur Divya , Tyagi Abhilash , Kumar Rajesh , Kumar Vinod , Olsen Carl E. , Saxena Rajendra K. , Prasad Ashok K. 
Published: April 2014

AbstractA series of triazoles (III) (9 examples) is readily synthesized by a Huisgen 1,3‐dipolar cycloaddition reaction of alkynes (II) with azide (I), which is chemoenzymatically prepared starting from D‐xylose.
ChemInform Abstract: New Orsellinic Acid Esters from Fungus Chaetomium globosporum.
Authors: Xu Guo‐Bo , Wang Ni‐Ni , Bao Jin‐Ku , Yang Tao , Li Guo‐You 
Published: April 2014

AbstractOrsellinic acid esters (I)—(VII) are obtained along with four known compounds from the solid, fermented rice culture of Chaetomium globosporum (cib‐132).
ChemInform Abstract: Limonoids and Flavonoids from the Flowers of Azadirachta indica var. siamensis, and Their Melanogenesis‐Inhibitory and Cytotoxic Activities.
Authors: Kitdamrongtham Worapong , Ishii Kenta , Ebina Kodai , Zhang Jie , Ukiya Motohiko , Koike Kazuo , Akazawa Hiroyuki , Manosroi Aranya , Manosroi Jiradej , Akihisa Toshihiro 
Published: April 2014

AbstractA new limonoid (I) and two new flavonoids (II) and (III) are isolated along with two known limonoids and seven known flavonoids.
ChemInform Abstract: Trapped in Misbelief for Almost 40 Years: Selective Synthesis of the Four Stereoisomers of Mefloquine.
Authors: Schuetzenmeister Nina , Mueller Michael , Reinscheid Uwe M. , Griesinger Christian , Leonov Andrei 
Published: April 2014

AbstractThe racemic erythro form of mefloquine is applied as an important anti malaria drug.
ChemInform Abstract: Evolution of Actinyl Peroxide Clusters U28 in Dilute Electrolyte Solution: Exploring the Transition from Simple Ions to Macroionic Assemblies.
Authors: Li Dong , Simotwo Silas , Nyman May , Liu Tianbo 
Published: April 2014

AbstractThe solution behavior of Cs15 [(Ta(O2)4)Cs4K12(UO2 (O2)1.5)28]·20H2O and Na6K9 [(Ta(O2)4)Rb4Na12 (UO2(O2)1.5)28] ·20H2O in aqueous KOH is investigated by dynamic and static laser‐light scattering, conductance measurements, and TEM.
ChemInform Abstract: Supramolecular Catalysis. Part1. Non‐Covalent Interactions as a Tool for Building and Modifying Homogeneous Catalysts
Authors: Raynal Matthieu , Ballester Pablo , Vidal‐Ferran Anton , van Leeuwen Piet W. N. M. 
Published: April 2014

AbstractReview: 605 refs.
ChemInform Abstract: Synthesis, Double‐Helix Formation, and Higher‐Assembly Formation of Chiral Polycyclic Aromatic Compounds: Conceptual Development of Polyketide Aldol Synthesis
Authors: Yamaguchi Masahiko , Shigeno Masanori , Saito Nozomi , Yamamoto Koji 
Published: April 2014

AbstractReview: [38 refs.
ChemInform Abstract: Carboxylic Acid Free Novel Isocyanide‐Based Reactions
Authors: Soeta Takahiro , Ukaji Yutaka 
Published: April 2014

AbstractReview: [design of novel Passerini‐ and Ugi‐type reaction systems where the carboxylic acid component has been replaced by compounds (Z—X) containing an electrophilic (Z) and a nucleophilic group (X); 40 refs.
Chiral Ligand‐Exchange Resolution of Underivatized Amino Acids on a Dynamically Modified Stationary Phase for RP‐HPTLC
Authors: Remelli Maurizio , Faccini Stefania , Conato Chiara 
Published: April 2014

ABSTRACTThe synthesis of Spi(τ‐dec), derived from the selective alkylation of L‐spinacine (4,5,6,7‐tetrahydro‐1H‐imidazo[4,5‐c]pyridine‐6‐carboxylic acid) at the τ‐nitrogen of its heteroaromatic ring, with a linear hydrocarbon chain of 10 carbon atoms, is described here for the first time. Spi(τ‐dec) was successfully employed in the past to prepare home‐made chiral columns for chiral ligand‐exchange high‐performance liquid chromatography. In the present article a new method is described, using Spi(τ‐dec) as a chiral selector in high‐performance thin‐layer chromatography (HPTLC): commercial hydrophobic plates were first coated with Spi(τ‐dec) and then treated with copper sulfate. The performance of this new chiral stationary phase was tested against racemic mixtures of aromatic amino acids, after appropriate optimization of both the conditions of preparation of the plates and the mobile phase composition. The enantioselectivity values obtained for the studied compounds were higher than those reported in the literature for similar systems. The method employed here for the preparation of chiral HPTLC plates proved practical, efficient, and inexpensive. Chirality 26:313–318, 2014. © 2014 Wiley Periodicals, Inc.
Numerical und Experimental Analysis of a ZigZag Air Classifier
Authors: Friedrich Jens , Winkler Thomas , Lieberwirth Holger 
Published: April 2014

AbstractDie Untersuchung der partikelfreien Strömung im Zickzack‐Sichter dient als Grundlage für die Simulation von Trennprozessen partikelbeladener Gase. Zuerst werden charakteristische Strömungskenngrößen in verschiedenen Messebenen am Versuchsstand experimentell erfasst, insbesondere Druckverhältnisse und Gasgeschwindigkeiten. Die Messergebnisse werden danach unter Anwendung ausgewählter Turbulenz‐Modelle mit den Lösungen der numerischen CFD‐Simulation verglichen. Abschließend werden Trennfunktionen für kugelförmige Glaspartikel gezeigt und diskutiert.
Hydrophobicity of Minerals Determined by Atomic Force Microscopy – A Tool for Flotation Research
Authors: Rudolph Martin , Peuker Urs Alexander 
Published: April 2014

AbstractThe mineral separation process flotation is fundamentally relying on hydrophobic interactions, which are still not entirely understood and heavily discussed in literature. Here, various possibilities to determine hydrophobic properties of mineral surfaces in water using the concept of colloidal probe atomic force microscopy are introduced. The method is based on the accepted theories of the hydrophobic effect of hydrophobic surfaces in water. Additionally, the hydrophobic parameters are correlated with microflotation experiments for magnetite and quartz surfaces.
Impact of adjuvant chemotherapy on long‐term employment of survivors of early‐stage breast cancer
Authors: Jagsi Reshma , Hawley Sarah T. , Abrahamse Paul , Li Yun , Janz Nancy K. , Griggs Jennifer J. , Bradley Cathy , Graff John J. , Hamilton Ann , Katz Steven J. 
Published: April 2014

BACKGROUNDMany women with early‐stage breast cancer are working at the time of diagnosis and survive without disease recurrence. The short‐term impact of chemotherapy receipt on employment has been demonstrated, but the long‐term impact merits further research.METHODSThe authors conducted a longitudinal multicenter cohort study of women diagnosed with nonmetastatic breast cancer between 2005 and 2007, as reported to the population‐based Los Angeles and Detroit Surveillance, Epidemiology, and End Results program registries. Of 3133 individuals who were sent surveys, 2290 (73%) completed a baseline survey soon after diagnosis and of these, 1536 (67%) completed a 4‐year follow‐up questionnaire.RESULTSOf the 1026 patients aged < 65 years at the time of diagnosis whose breast cancer did not recur and who responded to both surveys, 746 (76%) worked for pay before diagnosis. Of these, 236 (30%) were no longer working at the time of the follow‐up survey. Women who received chemotherapy as part of their initial treatment were less likely to be working at the time of the follow‐up survey (38% vs 27%; P = .003). Chemotherapy receipt at the time of diagnosis (odds ratio, 1.4; P = .04) was found to be independently associated with unemployment during survivorship in a multivariable model. Many women who were not employed during the survivorship period wanted to work: 50% reported that it was important for them to work and 31% were actively seeking work.CONCLUSIONSUnemployment among survivors of breast cancer 4 years after diagnosis is often undesired and appears to be related to the receipt of chemotherapy during initial treatment. These findings should be considered when patients decide whether to receive adjuvant chemotherapy, particularly when the expected benefit is low. Cancer 2014;120:1854–1862. © 2014 American Cancer Society.
Expression of G proteins in the olfactory receptor neurons of the newt Cynops pyrrhogaster: Their unique projection into the olfactory bulbs
Authors: Nakada Tomoaki , Hagino‐Yamagishi Kimiko , Nakanishi Koki , Yokosuka Makoto , Saito Toru R. , Toyoda Fumiyo , Hasunuma Itaru , Nakakura Takashi , Kikuyama Sakae 
Published: April 2014

ABSTRACTWe analyzed the expression of G protein α subunits and the axonal projection into the brain in the olfactory system of the semiaquatic newt Cynops pyrrhogaster by immunostaining with antibodies against Gαolf and Gαo, by in situ hybridization using probes for Gαolf, Gαo, and Gαi2, and by neuronal tracing with DiI and DiA. The main olfactory epithelium (OE) consists of two parts, the ventral OE and dorsal OE. In the ventral OE, the Gαolf‐ and Gαo‐expressing neurons are located in the apical and basal zone of the OE, respectively. This zonal expression was similar to that of the OE in the middle cavity of the fully aquatic toad Xenopus laevis. However, the Gαolf‐ and Gαo‐expressing neurons in the newt ventral OE project their axons toward the main olfactory bulb (MOB) and the accessory olfactory bulb (AOB), respectively, whereas in Xenopus, the axons of both neurons project solely toward the MOB. In the dorsal OE of the newt, as in the principal cavity of Xenopus, the majority of the neurons express Gαolf and extend their axons into the MOB. In the vomeronasal organ (VNO), the neurons mostly express Gαo. These neurons and quite a few Gαolf‐expressing neurons project their axons toward the AOB. This feature is similar to that in the terrestrial toad Bufo japonicus and is different from that in Xenopus, in which VNO neurons express solely Gαo, although their axons invariably project toward the AOB. We discuss the findings in the light of diversification and evolution of the vertebrate olfactory system. J. Comp. Neurol. 522:3501–3519, 2014. © 2014 Wiley Periodicals, Inc.
Validation of a Measure of Alliance for an Adolescent Inpatient Setting
Authors: Haggerty Greg , Siefert Caleb J. , Sinclair Samuel J. , Zodan Jennifer , Babalola Ronke , Blais Mark A. 
Published: April 2014

The link between alliance and treatment outcome is robust. Nevertheless, few, if any, self‐report measures exist to assess the alliance between hospitalized adolescents and their treatment team as a whole. The present study looks to extend the use of a brief self‐report measure of inpatient treatment alliance designed for adult inpatients to be used with adolescents. The scale is designed incorporating items that tap the three factors of alliance (bond, goals and collaboration) to assess the alliance that the patient has with his or her treatment team. Our results show that the Inpatient‐Treatment Alliance Scale is unifactoral, shows good psychometrics and is linked in theoretically meaningful ways to global clinician ratings of engagement in individual psychotherapy. Copyright © 2014 John Wiley & Sons, Ltd.Key Practitioner Message
Inpatient treatment of adolescents requires the assessment of alliance to be between the patient and his or her treatment team rather than an individual clinician.
Assessment of the alliance can benefit clinicians treating hospitalized adolescents especially because these patients are difficult to engage with in treatment.
This study shows that the Inpatient‐Treatment Alliance Scale is a promising measure for assessing treatment alliance on an adolescent inpatient setting.