bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluating the Construct Validity of the Charité Alarm Fatigue Questionnaire using Confirmatory Factor Analysis
Authors: Wunderlich Maximilian Markus , Krampe Henning , Fuest Kristina , Leicht Dominik , Probst Moriz Benedikt , Runge Julian , Schmid Sebastian , Spies Claudia , Weiß Björn , Balzer Felix , Poncette Akira-Sebastian ,   CAFQa Study Group Germany
Published: August 2024

Abstract

Background
The Charité Alarm Fatigue Questionnaire (CAFQa) is a 9-item questionnaire that aims to standardize how alarm fatigue in nurses and physicians is measured. We previously hypothesized that it has 2 correlated scales, one on the psychosomatic effects of alarm fatigue and the other on staff’s coping strategies in working with alarms.

Objective
We aimed to validate the hypothesized structure of the CAFQa and thus underpin the instrument’s construct validity.

Methods
We conducted 2 independent studies with nurses and physicians from intensive care units in Germany (study 1: n=265; study 2: n=1212). Responses to the questionnaire were analyzed using confirmatory factor analysis with the unweighted least-squares algorithm based on polychoric covariances. Convergent validity was assessed by participants’ estimation of their own alarm fatigue and exposure to false alarms as a percentage.

Results
In both studies, the χ2 test reached statistical significance (study 1: χ226=44.9; P=.01; study 2: χ226=92.4; P<.001). Other fit indices suggested a good model fit (in both studies: root mean square error of approximation <0.05, standardized root mean squared residual <0.08, relative noncentrality index >0.95, Tucker-Lewis index >0.95, and comparative fit index >0.995). Participants’ mean scores correlated moderately with self-reported alarm fatigue (study 1: r=0.45; study 2: r=0.53) and weakly with self-perceived exposure to false alarms (study 1: r=0.3; study 2: r=0.33).

Conclusions
The questionnaire measures the construct of alarm fatigue as proposed in our previous study. Researchers and clinicians can rely on the CAFQa to measure the alarm fatigue of nurses and physicians.
Twenty-Five Years of Progress—Lessons Learned From JMIR Publications to Address Gender Parity in Digital Health Authorships: Bibliometric Analysis
Authors: Meyer Annika , Streichert Thomas 
Published: August 2024

Background
Digital health research plays a vital role in advancing equitable health care. The diversity of research teams is thereby instrumental in capturing societal challenges, increasing productivity, and reducing bias in algorithms. Despite its importance, the gender distribution within digital health authorship remains largely unexplored.

Objective
This study aimed to investigate the gender distribution among first and last authors in digital health research, thereby identifying predicting factors of female authorship.

Methods
This bibliometric analysis examined the gender distribution across 59,980 publications from 1999 to 2023, spanning 42 digital health journals indexed in the Web of Science. To identify strategies ensuring equality in research, a detailed comparison of gender representation in JMIR journals was conducted within the field, as well as against a matched sample. Two-tailed Welch 2-sample t tests, Wilcoxon rank sum tests, and chi-square tests were used to assess differences. In addition, odds ratios were calculated to identify predictors of female authorship.

Results
The analysis revealed that 37% of first authors and 30% of last authors in digital health were female. JMIR journals demonstrated a higher representation, with 49% of first authors and 38% of last authors being female, yielding odds ratios of 1.96 (95% CI 1.90-2.03; P<.001) and 1.78 (95% CI 1.71-1.84; P<.001), respectively. Since 2008, JMIR journals have consistently featured a greater proportion of female first authors than male counterparts. Other factors that predicted female authorship included having female authors in other relevant positions and gender discordance, given the higher rate of male last authors in the field.

Conclusions
There was an evident shift toward gender parity across publications in digital health, particularly from the publisher JMIR Publications. The specialized focus of its sister journals, equitable editorial policies, and transparency in the review process might contribute to these achievements. Further research is imperative to establish causality, enabling the replication of these successful strategies across other scientific fields to bridge the gender gap in digital health effectively.
Establishing an Evaluation Indicator System for User Satisfaction With Hypertension Management Apps: Combining User-Generated Content and Analytic Hierarchy Process
Authors: He Yunfan , Chen Han , Xiang Peng , Zhao Min , Li Yingjun , Liu Yongcheng , Wang Tong , Liang Jun , Lei Jianbo 
Published: August 2024

Background
Hypertension management apps (HMAs) can be effective in controlling blood pressure, but their actual impact is often suboptimal. Establishing a user satisfaction evaluation indicator system for HMAs can assist app developers in enhancing app design and functionality, while also helping users identify apps that best meet their needs. This approach aims to improve the overall effectiveness of app usage.

Objective
This study aims to systematically collect data on HMAs and their user reviews in the United States and China. It analyzes app usage patterns and functional characteristics, identifies factors influencing user satisfaction from existing research, and develops a satisfaction evaluation indicator system to provide more accurate recommendations for improving user satisfaction.

Methods
We conducted a descriptive statistical analysis to assess the development status of HMAs in both countries and applied the task-technology fit model to evaluate whether the app functionalities align with business needs. We separately summarized the factors influencing user satisfaction in both countries from previous research, utilized the analytic hierarchy process to develop an evaluation indicator system for HMA user satisfaction, and calculated satisfaction levels. Based on these findings, we propose improvements to enhance app functionality and user satisfaction.

Results
In terms of current development status, there were fewer HMAs and user reviews in China compared with the United States. Regarding app functional availability, fewer than 5% (4/91) of the apps achieved a demand fulfillment rate exceeding 80% (8/10). Overall, user satisfaction in both countries was low.

Conclusions
In the United States, user satisfaction was lowest for advertising distribution, data synchronization, and reliability. By contrast, Chinese apps need improvements in cost efficiency and compatibility.
A Meta 20 do PNE e as contingências fiscais no Brasil: impactos na educação básica
Authors: Santos Ildenbergue Lins dos , Bezerra Fábio Marques 
Published: August 2024

Nesta pesquisa, com vistas a identificar os impactos das contingências fiscais no Brasil na educação brasileira, considerando mais especificamente os desafios do país não ter atingido a meta n. 20 do Plano Nacional de Educação (PNE), foi realizada uma pesquisa documental e bibliográfica, buscando em documentos oficiais do Ministério da Educação (MEC) e do Instituto Nacional de Estudos e Pesquisas Educacionais Anísio Teixeira (INEP), bem como em artigos publicados e indexados nas bases de dados da Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) e da Biblioteca Digital Brasileira de Teses e Dissertações (BDTD). A partir deste estudo foi possível ratificar os desafios para o alcance de metas do PNE (2014-2024) frente às contingências fiscais no Brasil, destacando-se, principalmente, a meta 20 que diz respeito ao financiamento da educação. Com previsão de queda nas receitas disponíveis para a educação e crescimento das despesas educacionais, os cenários previstos demonstram um déficit e a incapacidade de financiamento, evidenciando que a meta n. 20 do PNE não será atingida dentro do prazo previsto, com impactos na educação que envolvem o comprometimento da infraestrutura escolar, formação dos professores, disponibilidade de materiais didáticos e apoio pedagógico, ampliando desigualdades e prejudicando a qualidade do ensino.
EVALUASI PENGGUNAAN ANTIVIRUS PASIEN COVID-19 DI INSTALASI RAWAT INAP RUMAH SAKIT DI DAERAH PURWOREJO TAHUN 2022
Authors: Purwantari Vinca Elyana , Ainni Ayu Nissa , Miyarso Chondrosuro , Hidayat Wahidin 
Published: August 2024

COVID-19 merupakan penyakit menular yang disebabkan oleh virus SARS-CoV-2. Kasus COVID-19 hingga saat ini masih adaan terapi COVID-19 masih beragam. Salah satu terapi yang digunakan adalah antivirus. Penelitian ini bertujuan untuk mengetahui pola penggunaan dan mengevaluasi ketepatan penggunaan antivirus pada pasien dewasa COVID-19 di instalasi rawat inap rumah sakit di daerah Purworejo Periode 2022. Metode penelitian ini menggunakan penelitian kualitatif dengan cara observasional menggunakan rancangan deskriptif non eksperimental dan bersifat rektrospektif. Data obat yang diperoleh dibandingkan dengan Pedoman Tatalaksana COVID-19 edisi IV Tahun 2022. Hasil Penelitian diperoleh sampel sebanyak 100 pasien COVID-19 di rawat inap Rumah Sakit (X) di Kabupaten Purworejo Periode 2022. Antivirus yang paling banyak diresepkan adalah Favipiravir sebanyak 97 pasien (97%) dan Remdesivir sebanyak 3 pasien (3%). Evaluasi penggunaan obat Favipiravir dan Remdesivir berdasarkan Pedoman Tatalaksana COVID-19 edisi IV yaitu 100% tepat indikasi, tepat dosis, tepat obat, tepat cara pemberian, dan 92% tepat lama pemberian. Berdasarkan hasil evaluasi ketepatan penggunaan antivirus Favipiravir dan Remdesivir pada pasien dewasa COVID-19 yaitu tepat indikasi (100%), tepat obat (100%), tepat dosis (100%), tepat cara pemberian (100%), dan tepat lama pemberian (92%).
AKTIVITAS IMUNOMODULATOR EKSTRAK ETANOL 70% DAUN TALOK (Muntingia calabura L.) TERHADAP RESPON IMUN NON SPESIFIK PADA MENCIT JANTAN GALUR SWISS WEBSTER
Authors: Sujono Tanti Azizah , Fakhrudin Muh. 
Published: August 2024

Daun talok (Muntingia calabura L.) dengan kandungan flavonoid memiliki aktivitas antioksidan sehingga berpotensi dikembangkan sebagai pengobatan alternatif dan agen imunostimulan. Penelitian ini bertujuan untuk mengetahui aktivitas imunomodulator ekstrak etanol 70% daun talok (EEDT) terhadap respon imun non spesifik. Penelitian eksperimental dengan rancangan acak lengkap (RAL) dengan variabel bebas peringkat dosis EEDT 50, 100 dan 200 mg/kgBB selama 7 hari secara peroral. Uji respon imun non spesifik ini menggunakan metode bersihan karbon dan indeks organ limfoid yang dilakukan pada mencit. Data dianalisis menggunakan uji parametrik one way ANOVA untuk indeks fagositik dan indeks organ limfoid. Hasil uji bersihan karbon menunjukkan bahwa EEDT dosis 50 mg/kgBB tidak berefek imunostimulan dengan indeks fagositik 1,165; dosis 100 mg/kgBB bersifat imunostimulan sedang dengan indeks fagositik 1,311; sedangkan EEDT dosis 200 mg/kgBB bersifat imunostimulan kuat dengan indeks fagositik 2,839. Peningkatan bobot limpa pada hasil uji indeks organ limfoid menunjukkan adanya efek ekstrak etanol 70% daun talok terhadap aktivitas imunostimulan. Hasil skrining fitokimia EEDT terbukti mengandung senyawa golongan alkaloid, flavonoid, saponin, tanin dan steroid. Berdasarkan hasil yang didapat maka disimpulkan bahwa pemberian EEDT 100 dan 200 mg/kgBB selama 7 hari menunjukkan aktivitas imunostimulan.
Research on basketball training health smart monitoring system based on picture sequence analysis
Authors: Yang Honglin , Chen Shu , Li Zhanping , Hu Yijun , Zhen Juan , Zhou Taigeng , Jeong Yeontag 
Published: August 2024

Abstract
At present, exercises have become a frequent international competitive exchange activity. To some extent, a country's exercise level also measures the country's comprehensive economic strength. The holding of various international and domestic exercise events directly leads to the explosive increase of exercise videos digital. Therefore, efficient exercise video analysis is necessary. With the expansion of multimedia techniques and the emergence of message highways, the storage and transmission of digital video is no longer a difficult thing. The holding of different exercise events directly leads to the explosive increase of exercise videos. Therefore, efficient exercise video analysis is very necessary. Computer techniques have injected new vitality into most industries, but their expansion in the exercise industry is relatively slow. The means used in this paper is picture sequence analysis. The basic operation of sequence picture analysis is to detect motion messages or aims from picture sequences. It is a very active branch of picture courseing and computer sight. Because it has been widely used in many aspects of national eco and military, its research has attracted the general concentration of scientists all over the world.
Research on the Relationship between Knowledge Management Strategy and Enterprise Performance Based on Regression Analysis
Authors: Xiong Xia 
Published: August 2024

Abstract
By evaluating three characteristics of knowledge management strategies and their relationship to business outcomes, this paper examines the current state of business lore management and its influence on show and analyzes some of the existing issues related to knowledge management. Enterprise performance has a strong positive correlation with innovation capability, process capability, and facility capability, the correlation with process capability is 0.796, the correlation with innovation capability is 0.834, and the correlation with facility capability is 0.796. Among them, innovation capability has the largest contribution to performance, followed by process and facility capability; in general, innovation capability is a larger investment than facility capability. In process capability, knowledge use plays an important role, followed by knowledge transmission and knowledge collection. and knowledge protection; in terms of innovation capacity, cultural factors contribute more, and cultural elements play a more obvious part in the growth of innovation capacity, followed by incentives and strategies; in terms of facility capacity, process capacity is slightly smaller than the contribution of innovation capacity, Through the relationship between enterprise performance and knowledge management strategy, it can be reflected by evaluating each of the indicators affecting the above three options.
Construction of an information-based English teaching quality evaluation system based on the fusion of multimedia English educational resources
Authors: Zhou Ling 
Published: August 2024

Abstract
Today's information technology is constantly evolving, multimedia teaching, a new form of classroom teaching, has long been widely used by colleges. However, in many colleges, its teaching advantages have not been fully exerted, although the school spends a lot of human, data, and financial resources to publicize and promote multimedia classroom teaching, the effect of multimedia classroom teaching is not very good. There are many reasons for this, including the lack of an effective evaluation system to guide teachers in their teaching activities. Therefore, the top priority is Establishing a correct and appropriate multimedia English teaching evaluation index system. Starting from the characteristics and requirements of multimedia classroom teaching, this paper constructs a multimedia classroom teaching evaluation index system in colleges and universities based on the problems faced by current multimedia classroom teaching, promoting the quality of teaching in multimedia English classrooms through the English Teaching Evaluation System - the medium between theory and practice. The teacher teaching quality evaluation system studied in the thesis can completely solve the problem of unreasonable evaluation of teacher learning quality, and provide an integrated teaching quality evaluation model for students, teachers, and academic affairs offices. The system has changed the original evaluation method and constructed a teaching quality evaluation model that integrates. Data collection, evaluation management, online evaluation, and teaching resource data management, to achieve fair, scientific, and comprehensive evaluation, and provide a comprehensive management and analysis platform for comprehensively mastering evaluation of multimedia English teaching quality.
The Role of Artificial Intelligence in Space Medicine
Authors: Greatbatch Connor 
Published: August 2024

Abstract
Space is considered to be the most inhospitable environment known to man. A lack of oxygen, microgravity, extremes of temperature, ionising radiation and the inability to grow food being only a few of the challenges that space exploration may pose to those brave enough to travel there.(1) Consequently, astronauts encountered numerous health risks primarily due to the effects of microgravity and ionising radiation as well as the psychological impacts of isolation and confinement.(2,3) Because of this, it is imperative that the health and wellbeing of astronauts be monitored closely to ensure their safety. This is currently achieved via telemedicine, in which medical personnel on earth communicate with those in space. However, this is not without limitations such as the inability to physically examine those in space and communication delays that may be encountered due to the vast transmission distances. In the case that communications become compromised or infeasible, astronauts may be left vulnerable to a wide range of potential health complications. Therefore, a redundancy solution to monitor astronaut health alongside direct astronaut-to-earth communication is required. This could be achieved via the use of artificial intelligence (AI). AI allows for the health of astronauts to be automatically monitored and provides an effective solution to some of the biological and psychological issues that astronauts encounter. This essay explores the role of AI in a selection of health issues encountered by astronauts.
Evaluation of soil properties variability along a toposequence in Wasinmi, Southwest Nigeria
Authors: Oyebiyi Oluwatoyosi Oyetola , Fagbohun Usman Olaleke , Egbinola Oluwatosin Abimbola , Ojetade Julius Olayinka , Muda Sikiru Adekoya , Adewumi Opeyemi Ayomide 
Published: August 2024

Abstract
Topography significantly influences soil development and characteristics within an uneven agricultural field. Therefore, a comprehensive understanding of soil attributes and processes through detailed pedological knowledge is crucial for effective soil management. This research was carried out in Wasinmi, southwestern Nigeria, to delineate and categorise the soils across different slopes for agricultural insights. Three soil profiles were excavated across the topographical sequence, specifically designated as upper, middle, and lower slope positions. The prevailing soil texture was sandy loam with a discernible trend of lighter soil colour as the slope descended and soil depth increased. The pH of the soil ranged from moderately acidic to slightly acidic. The saturated hydraulic conductivity and soil organic matter content were lowest on the lower slope. Available phosphorus distribution varied inconsistently with higher concentrations of heavy minerals observed at the upper slope. The study underscored the influential role of topography in soil property variations and the need for tailored management practices. The classification of the soils revealed Typic Plintustults in the upper and middle slope positions, while the soils in the lower slope were identified as Typic Kandiaquults. This study demonstrated that topography significantly influenced soil properties, thereby emphasising the need for informed practices to better support the long-term sustainability of land use and agricultural outputs in topographically diverse landscapes.
Wnt1 gene expression in the heart left ventricle as a response to the various durations of the intensive exercise: An experimental study
Authors: Sheikhzadeh Farzam , Khajehnasiri Nazli , Khalaj-Kondori Mohammad , Ramouz Ali , Sadeghian Reihaneh 
Published: August 2024

Abstract

Objective. Myocardial fibrosis is a devastating condition causing millions of deaths yearly. Several factors, such as aging, cause myocardial fibrosis. The Wnt/β-catenin pathway is one of the critical intracellular signaling for the development of cardiac fibrosis. Molecular and cellular mechanism of myocardial fibrosis induced by intensive exercise is not well-understood. The current study evaluates the effects of short- and long-term intensive exercise on the Wnt1 gene expression in a heart left ventricle in an animal model.

Methods. Twenty-one male Wistar rats (mean weight 250±50 g) were divided into three groups (n=7): 1) control group (C); 2) short-term regular intensive exercise group (S-RIE, high-intensity exercise for one month six days weekly for 60 min with speed of 35 m/min), and 3) long-term regular intensive exercise group (L-RIE, high-intensity exercise for six months six days daily for 60 min with speed of 35 m/min). The heart left ventricle was isolated at the end of the experiment, and the relative gene expression of the Wnt1 gene was measured by the Real-Time PCR.

Results. The L-RIE group showed a significant increase in the Wnt1 expression compared to the S-RIE and the control group. Although no difference was observed in the Wnt1 mRNA level in the S-RIE group compared to the control group, Wnt1 mRNA level increased in the L-RIE group compared to the S-RIE group.

Conclusion. The exercise duration was of a great importance in the Wnt1 gene expression. Regular intensive exercise may be involved in the formation of the myocardial fibrosis by increasing the expression of the Wnt1 gene.
Unique hyaluronan structure of expanded oocyte-cumulus extracellular matrix in ovarian follicles
Authors: Nagyova Eva , Mlynarcikova Alzbeta Bujnakova , Nemcova Lucie , Scsukova Sona 
Published: August 2024

Abstract
In preovulatory follicles, after the endogenous gonadotropin surge, the oocyte-cumulus complexes (OCCs) produce hyaluronan (HA) in a process called “cumulus expansion”. During this process, the heavy chains (HCs) of the serum-derived inter-alpha-trypsin inhibitor (IαI) family bind covalently to synthesized HA and form a unique structure of the expanded cumulus HA-rich extracellular matrix. Understanding the biochemical mechanism of the covalent linkage between HA and the HCs of the IαI family is one of the most significant discoveries in reproductive biology, since it explains basis of the cumulus expansion process running in parallel with the oocyte maturation, both essential for ovulation. Two recent studies have supported the above-mentioned findings: in the first, seven components of the extracellular matrix were detected by proteomic, evolutionary, and experimental analyses, and in the second, the essential role of serum in the process of cumulus expansion in vitro was confirmed. We have previously demonstrated the formation of unique structure of the covalent linkage of HA to HCs of IαI in the expanded gonadotropin-stimulated OCC, as well as interactions with several proteins produced by the cumulus cells: tumor necrosis factor-alpha-induced protein 6, pentraxin 3, and versican. Importantly, deletion of these genes in the mice produces female infertility due to defects in the oocyte-cumulus structure.