bluuebunny/crossref_metadata_2025_split huggingface dataset:
The relationship between sensory processing disorders and eating problems among children with intellectual developmental deficits
Authors: Engel-Yeger Batya , Hardal-Nasser Reem , Gal Eynat 
Published: July 2015

Introduction Sensory processing disorders are prevalent among children with intellectual developmental deficits and negatively impact their daily routines. Eating, which is a major part of daily routines, is known to be frequently impaired among children with intellectual developmental deficits. This study aimed to examine the relationships between sensory processing disorders and eating problems in children with different levels of intellectual developmental deficit. Method Participants were 91 children aged 4 to 9 years: 25 with mild intellectual developmental deficits, 32 with moderate intellectual developmental deficits and 34 with severe/profound intellectual developmental deficits. All participants were recruited from special education kindergartens/schools for children with intellectual developmental deficits. Participants' primary caregiver in school completed the screening tool of eating problems and the short sensory profile. Findings Significant correlations between sensory processing disorders and eating problems were found in each intellectual developmental deficit level ( r = −.40, p ≤ .05 to r = −.57, p ≤ .001), but most correlations were found among children with moderate and severe/profound level. Energy level significantly predicted aspiration frequency; smell/taste sensitivity significantly predicted food selectivity and food refusal frequency. Conclusion Eating problems should be screened among children with intellectual developmental deficits according to intellectual developmental deficit severity and other related factors such as sensory processing disorders. Applying this approach in occupational therapy intervention may contribute to a child's adaptive behaviour and performance in daily routines.
Strategies used by older women with intellectual disability to create and maintain their social networks: An exploratory qualitative study
Authors: White Katharine , Mackenzie Lynette 
Published: July 2015

Introduction Social networks are important to health and wellbeing, and enhancing social networks are key occupations for older people. This is relevant for older people with intellectual disability, particularly older women, who face challenges in building social networks, and their social networks are vulnerable to loss as they age. This study aimed to investigate how older women with intellectual disability create and maintain their social networks. Method This exploratory qualitative study involved conducting in-depth interviews with five women with mild to moderate intellectual disability (as defined by their service organisation) aged over 50 years and living in the community, using the Support Interview Guide, that has previously been used with younger adults with intellectual disability. Participants could communicate in spoken English. Data were coded line by line and analysed using a thematic analysis. Results Participants created social networks independently and through others. Strategies used included communicating, sharing activities, celebrating special occasions, organising activities, supporting each other, having a routine, being out and about and using formal assistance. Barriers and facilitators were also identified. Conclusion As older women with intellectual disability age, occupational therapists and support organisations need to focus on assisting this group to build and maintain their social networks.
Gut feelings 1. Mind, mood and gut in irritable bowel syndrome: approaches to psychiatric care
Authors: Keightley Philip , Pavli Paul , Platten Jan , Looi Jeffrey CL 
Published: July 2015

Objective: Psychiatrists are likely to encounter patients with irritable bowel syndrome (IBS). We aim to provide a clinically-focused summary of psychiatric comorbidities and management. Conclusions: IBS affects up to 15% of the population. Antidepressants and brief psychotherapy can reduce symptom severity and improve coping. These treatments are effective for patients without comorbid mental illness, as well as those with increased somatisation, health-care seeking and sexual abuse histories.
Primary angiocentric/angioinvasive T-cell lymphoma of the tympanic bulla in a feline leukaemia virus-positive cat
Authors: Santagostino Sara F , Mortellaro Carlo M , Buchholz Julia , Lugli Margherita , Forlani Annalisa , Ghisleni Gabriele , Roccabianca Paola 
Published: July 2015

Case summary A 5-year-old neutered female feline leukaemia virus (FeLV)-positive domestic shorthair cat with a 5 month history of otitis media was referred for head tilt, stertor and dyspnoea. Computed tomography scan revealed soft tissue opacities inside the right tympanic bulla, with bone remodelling, and concurrent nasopharyngeal and intracranial invasion. Endoscopically guided bioptic samples were collected from the nasopharynx and middle ear. Histology revealed dense sheets of round, large, neoplastic cells, often surrounding or invading vascular walls. Neoplastic cells expressed CD3, FeLV p27 and gp70 antigens. A middle ear angiocentric/angioinvasive T-cell lymphoma was diagnosed. After improvement of clinical conditions following radiation therapy, the cat died unexpectedly. At necropsy, hepatic and splenic spread was detected. Relevance and novel information Primary middle ear tumours are rare and their diagnosis is often delayed as clinical signs mimic more common otological conditions. Multiple bioptic specimens are pivotal for a definitive diagnosis. The young age of the cat, serology and immunohistochemistry revealed a possible transforming role of FeLV.
Multicolor Photodetector of a Single Er3+-Doped CdS Nanoribbon
Authors: Dedong Hou , Ying-Kai Liu , Yu De-Peng 
Published: July 2015

AbstractEr3+-doped CdS nanoribbons (Er-CdS NRs) are synthesized by thermal evaporation and then characterized by field emission scanning electron microscopy (FE-SEM), high-resolution transmission electron microscopy (HRTEM), photoluminescence (PL), and absorption spectra. The Er-CdS NR photodetector is studied systematically, including spectral response, light intensity response, and photoconductance (G) versus temperature (T). It is found that Er-CdS NR has the ability of detecting multicolor light including blue, red, and near-infrared light with higher responsivity (Rλ) and external quantum efficiency (η). The conductance of Er-CdS NR under dark conditions decreases with increasing temperature in the range of 87–237 K, while its conductance increases with increasing temperature in the range of 237–297 K whenTis larger than 237 K. These results indicated that ionized impurities and the intrinsic excitation are responsible for the conductance change of Er-CdS NR in the dark. The superior performance of the Er-CdS NR device offers an avenue to develop highly sensitive multicolor photodetector applications.
Economic impact of homeopathic practice in general medicine in France
Authors: Colas Aurélie , Danno Karine , Tabar Cynthia , Ehreth Jenifer , Duru Gérard 
Published: July 2015

Abstract
Health authorities are constantly searching for new ways to stabilise health expenditures. To explore this issue, we compared the costs generated by different types of medical practice in French general medicine: i.e. conventional (CM-GP), homeopathic (Ho-GP), or mixed (Mx-GP).
Data from a previous cross-sectional study, EPI3 La-Ser, were used. Three types of cost were analysed: (i) consultation cost (ii) prescription cost and (iii) total cost (consultation + prescription). Each was evaluated as: (i) the cost to Social Security (ii) the remaining cost (to the patient and/or supplementary health insurance); and (iii) health expenditure (combination of the two costs).
With regard to Social Security, treatment by Ho-GPs was less costly (42.00 € vs 65.25 € for CM-GPs, 35 % less). Medical prescriptions were two-times more expensive for CM-GPs patients (48.68 € vs 25.62 €). For the supplementary health insurance and/or patient out-of-pocket costs, treatment by CM-GPs was less expensive due to the lower consultation costs (6.19 € vs 11.20 € for Ho-GPs) whereas the prescription cost was comparable between the Ho-GPs and the CM-GPs patients (15.87 € vs 15.24 € respectively) . The health expenditure cost was 20 % less for patients consulting Ho-GPs compared to CM-GPs (68.93 € vs 86.63 €, respectively). The lower cost of medical prescriptions for Ho-GPs patients compared to CM-GPs patients (41.67 € vs 63.72 €) was offset by the higher consultation costs (27.08 € vs 22.68 € respectively). Ho-GPs prescribed fewer psychotropic drugs, antibiotics and non-steroidal anti-inflammatory drugs.
In conclusions management of patients by homeopathic GPs may be less expensive from a global perspective and may represent an important interest to public health.
Order-preservation of solution correspondence for parametric generalized variational inequalities on Banach lattices
Authors: Wang Yuehu , Zhang Congjun 
Published: July 2015

AbstractIn this paper, several order-theoretic fixed point theorems are proved on Banach lattices. As applications of these fixed point theorems, we study the order-preservation of solution correspondence for parametric generalized variational inequalities. Furthermore, the existence of solutions to equilibrium problems is also examined. Our approach is order-theoretic and all results obtained in this paper do not require the considered mappings to be continuous or semi-continuous with respect to any topology equipped on the underlying space.
Strain gradient elasticity with geometric nonlinearities and its computational evaluation
Authors: Abali B Emek , Müller Wolfgang H , Eremeyev Victor A 
Published: July 2015

Abstract
Background
The theory of linear elasticity is insufficient at small length scales, e.g., when dealing with micro-devices. In particular, it cannot predict the “size effect” observed at the micro- and nanometer scales. In order to design at such small scales an improvement of the theory of elasticity is necessary, which is referred to as strain gradient elasticity.

Methods
There are various approaches in literature, especially for small deformations. In order to include geometric nonlinearities we start by discussing the necessary balance equations. Then we present a generic approach for obtaining adequate constitutive equations. By combining balance equations and constitutive relations nonlinear field equations result. We apply a variational formulation to the nonlinear field equations in order to find a weak form, which can be solved numerically by using open-source codes.

Results
By using balances of linear and angular momentum we obtain the so-called stress and couple stress as tensors of rank two and three, respectively. Since dealing with tensors an adequate representation theorem can be applied. We propose for an isotropic material a stress with two and a couple stress with three material parameters. For understanding their impact during deformation the numerical solution procedure is performed. By successfully simulating the size effect known from experiments, we verify the proposed theory and its numerical implementation.

Conclusion
Based on representation theorems a self consistent strain gradient theory is presented, discussed, and implemented into a computational reality.
Bias Correction Methods Explain Much of the Variation Seen in Breast Cancer Risks of BRCA1/2 Mutation Carriers
Authors: Vos Janet R. , Hsu Li , Brohet Richard M. , Mourits Marian J.E. , de Vries Jakob , Malone Kathleen E. , Oosterwijk Jan C. , de Bock Geertruida H. 
Published: July 2015

Purpose Recommendations for treating patients who carry a BRCA1/2 gene are mainly based on cumulative lifetime risks (CLTRs) of breast cancer determined from retrospective cohorts. These risks vary widely (27% to 88%), and it is important to understand why. We analyzed the effects of methods of risk estimation and bias correction and of population factors on CLTRs in this retrospective clinical cohort of BRCA1/2 carriers. Patients and Methods The following methods to estimate the breast cancer risk of BRCA1/2 carriers were identified from the literature: Kaplan-Meier, frailty, and modified segregation analyses with bias correction consisting of including or excluding index patients combined with including or excluding first-degree relatives (FDRs) or different conditional likelihoods. These were applied to clinical data of BRCA1/2 families derived from our family cancer clinic for whom a simulation was also performed to evaluate the methods. CLTRs and 95% CIs were estimated and compared with the reference CLTRs. Results CLTRs ranged from 35% to 83% for BRCA1 and 41% to 86% for BRCA2 carriers at age 70 years width of 95% CIs: 10% to 35% and 13% to 46%, respectively). Relative bias varied from −38% to +16%. Bias correction with inclusion of index patients and untested FDRs gave the smallest bias: +2% (SD, 2%) in BRCA1 and +0.9% (SD, 3.6%) in BRCA2. Conclusion Much of the variation in breast cancer CLTRs in retrospective clinical BRCA1/2 cohorts is due to the bias-correction method, whereas a smaller part is due to population differences. Kaplan-Meier analyses with bias correction that includes index patients and a proportion of untested FDRs provide suitable CLTRs for carriers counseled in the clinic.
Race and Insurance Differences in the Receipt of Adjuvant Chemotherapy Among Patients With Stage III Colon Cancer
Authors: Murphy Caitlin C. , Harlan Linda C. , Warren Joan L. , Geiger Ann M. 
Published: July 2015

Purpose Although the incidence and mortality of colon cancer in the United States has declined over the past two decades, blacks have worse outcomes than whites. Variations in treatment may contribute to mortality differentials. Methods Patients diagnosed with stage III colon cancer were randomly sampled from the SEER program from the years 1990, 1991, 1995, 2000, 2005, and 2010. Patients were categorized as non-Hispanic white (n = 835) or black (n = 384). Treatment data were obtained from a review of the medical records, and these data were verified through contact with the original treating physicians. Log-binomial regression models were used to estimate the association between race and receipt of adjuvant chemotherapy. Effect modification by insurance was assessed with use of single referent models. Results Receipt of adjuvant chemotherapy among both white and black patients increased from the period encompassing the years 1990 and 1991 (white, 58%; black, 45%) to the year 2005 (white, 72%; black, 71%) and then decreased in the year 2010 (white, 66%; black, 57%). There were marked racial disparities in the time period of 1990 to 1991 and again in 2010, with black patients less likely to receive adjuvant chemotherapy as compared with white patients (risk ratio [RR], .82; 95% CI, .72 to .93). For black patients, receipt of adjuvant chemotherapy did not differ across insurance categories (RR for private insurance, .80; 95% CI, .69 to .93; RR for Medicare, .84; 95% CI, .69 to 1.02; and RR for Medicaid, .84; 95% CI, .69 to 1.02), although a larger proportion had Medicaid in all years of the study as compared with white patients. Conclusion The chemotherapy differential narrowed after the time period of 1990 to 1991, but our findings suggest that the disparity reemerged in 2010. Recent decreases in chemotherapy use may be due, in part, to the economic downturn and an increase in Medicaid coverage.
Thyrospheres From Normal or Malignant Thyroid Tissue Have Different Biological, Functional, and Genetic Features
Authors: Gianì Fiorenza , Vella Veronica , Nicolosi Maria Luisa , Fierabracci Alessandra , Lotta Sonia , Malaguarnera Roberta , Belfiore Antonino , Vigneri Riccardo , Frasca Francesco 
Published: July 2015

Context:
Cancer stem cells from several human malignancies, including poorly differentiated thyroid carcinoma and thyroid cancer cell lines, have been cultured in vitro as sphere-forming cells. These thyroid cancer stem cells were proven to be able to reproduce the original tumor in a xenograft orthotopic model.

Objectives:
The objective of the study was to characterize papillary thyroid carcinoma (PTC) spheres from well-differentiated thyroid cancer and normal thyroid (NT) spheres obtained from the contralateral thyroid tissue of the same patient.

Design:
Thyrospheres from PTCs and NTs were isolated.

Main Outcome Measures:
Gene expression analysis by real-time PCR, immunofluorescence studies, and fluorescence-activated cell sorter analysis in thyrospheres from PTCs and NTs have been evaluated.

Conclusions:
Compared with NT spheres, PTC spheres are larger, more irregular, and more clonogenic and have a higher rate of symmetric division. Moreover, PTC spheres express higher levels of stem cell markers and lower levels of thyroid-specific genes compared with NT spheres. Under appropriate conditions, NT spheres differentiated into thyrocytes, whereas PTC spheres did not, displaying a defect in the differentiation potential. Immunofluorescence experiments indicated that, in NT spheres, progenitor cells are mainly present in the sphere core, and the sphere periphery contains thyroid precursor cells already committed to differentiation. PTC spheres are not polarized like NT spheres. Unlike cells differentiated from NT spheres, TSH did not significantly stimulate cAMP production in cells differentiated from PTC spheres. A microarray analysis performed in paired samples (NT and PTC spheres from the same patient) indicated that NT and PTC spheres display a gene expression pattern typical of stem/progenitor cells; however, compared with NT spheres, PTC spheres display a unique gene expression pattern that might be involved in PTC progression.
Connecting the pieces: Using ORCIDs to improve research impact and repositories
Authors: Baessa Mohamed , Lery Thibaut , Grenz Daryl , Vijayakumar J. K. 
Published: July 2015

Quantitative data are crucial in the assessment of research impact in the academic world. However, as a young university created in 2009, King Abdullah University of Science and Technology (KAUST) needs to aggregate bibliometrics from researchers coming from diverse origins, not necessarily with the proper affiliations. In this context, the University has launched an institutional repository in September 2012 with the objectives of creating a home for the intellectual outputs of KAUST researchers. Later, the university adopted the first mandated institutional open access policy in the Arab region, effective June 31, 2014. Several projects were then initiated in order to accurately identify the research being done by KAUST authors and bring it into the repository in accordance with the open access policy. Integration with ORCID has been a key element in this process and the best way to ensure data quality for researcher’s scientific contributions. It included the systematic inclusion and creation, if necessary, of ORCID identifiers in the existing repository system, an institutional membership in ORCID, and the creation of dedicated integration tools. In addition and in cooperation with the Office of Research Evaluation, the Library worked at implementing a Current Research Information System (CRIS) as a standardized common resource to monitor KAUST research outputs. We will present our findings about the CRIS implementation, the ORCID API, the repository statistics as well as our approach in conducting the assessment of research impact in terms of usage by the global research community.
Systematic Review and Meta-analysis of Prevalence of Coronary Artery Disease in Adult Patients with Cardiac Myxomas
Authors: Silva Matheus , Carneiro Matheus , Nunes Júlio , da Silva Antônio , de Sousa Marcos 
Published: July 2015

Background: Studies have reported varied prevalence estimates of coronary artery disease (CAD) in cardiac myxoma patients. We performed a systematic review and meta-analysis of observational studies to summarize the point prevalence of CAD in adults with cardiac myxomas. Methods and Results: Two independent investigators searched MEDLINE and LILACS databases using the terms "Myxoma”, "Coronary Angiography" and "Coronary Disease" from inception through December 2014 for all relevant studies. We included 6 observational studies. Publication bias was evaluated through Egger's test and Trim and Fill method. A pooled estimate of CAD prevalence with corresponding 95% confidence interval (CI) was calculated based on a random-effects model. The pooled CAD prevalence in adult cardiac myxoma patients was 20.7% with low heterogeneity (I2 = 14.86%). Conclusions: It is a matter of debate if preoperative coronary angiography must be done as a routine procedure. Although coronary disease and angiographically detectable neovascularity can alter surgical management, more studies are needed to evaluate this question.
Iatrogenic Aortic Transection in a Child
Authors: Sherawat Ram , Sharma Anil , Dixit Sunil , Sharma Mohit , Lukaram Sidarth 
Published: July 2015

AbstractThe accepted treatment for aortic injury has been repair of the injury as soon as possible. Delayed repair is not generally fruitful, but in our case report, delay in the repair of a ligated and transected abdominal aorta is safe and has a potential positive impact on survival and vascular stability/integrity. This case seems worth reporting.
Staged Hybrid Endovascular Repair of a Ruptured Abdominal Aortic Aneurysm with Aortocaval Fistula
Authors: Chung Sandra , Reid Chris , Bandyk Dennis , Barleben Andrew , Lane John 
Published: July 2015

AbstractThere is a growing body of literature expanding the indication of endovascular aneurysm repair, from prophylactic treatment of aneurysms to other indications such as ruptured and complicated ruptured abdominal aneurysms. Concomitant aortocaval fistula is rare, and reports of open and endovascular repair exist. We report a unique hybrid approach to a case of a ruptured abdominal aortic aneurysm with aortocaval fistula, repaired primarily via endovascular approach in a hybrid, two-staged fashion. Representative images are presented in addition to a short review of this pathology.
HCAs acquire work experience in a simulated hospital with manikins at the University of Bedfordshire
Authors: Kpodo Charles , Kemp Anthony , Adams Louise , Burden Barbara 
Published: July 2015

Healthcare Assistants (HCAs) are important members of the care team. This article looks at how experience in a simulated hospital can enhance their skills. This is achieved in a safe environment where the only consequence of a mistake is learning. The simulated hospital at the University of Bedfordshire is an immersive and fully authentic learning experience. It encapsulates a range of clinical areas that allows HCAs and others to work shifts caring for a range of interactive patients. Through focusing on the First Step Competence Checklist developed by the RCN, the simulated hospital allows HCAs to develop their confidence and competence in their caring skills, while also becoming familiar with the totality of the healthcare environment.