bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Expeditious Synthesis of Ivacaftor.
Authors: Shen Jingshan , He Yang , Xu Qien , Ma Wenpeng , Zhang Jian , Sun Hongbing 
Published: September 2014

AbstractScale‐up of the presented 6 step synthesis starting from 2‐nitrobenzoyl chloride and giving the title compound in 39% yield is in progress.
ChemInform Abstract: A Concise [C + NC + CC] Coupling‐Enabled Synthesis of Kaitocephalin.
Authors: Garner Philip , Weerasinghe Laksiri , Van Houten Ian , Hu Jieyu 
Published: September 2014

AbstractThe synthesis of the iGenR antagonist kaitocephalin from aspartic acid is achieved in 15 steps.
ChemInform Abstract: Ferromagnetic Behaviour of Fe‐Doped ZnO Nanograined Films
Authors: Straumal Boris B. , Protasova Svetlana G. , Mazilkin Andrei A. , Tietze Thomas , Goering Eberhard , Schuetz Gisela , Straumal Petr B. , Baretzky Brigitte 
Published: September 2014

AbstractReview: 74 refs.
ChemInform Abstract: Transition Metal Complexes and Radical Anion Salts of 1,10‐Phenanthroline Derivatives Annulated with a 1,2,5‐Thiadiazole and 1,2,5‐Thiadiazole 1,1‐Dioxide Moiety: Multidimensional Crystal Structures and Various Magnetic Properties
Authors: Shuku Yoshiaki , Awaga Kunio 
Published: September 2014

AbstractReview: 78 refs.
Aimed information quantity in text
Authors: Chen Jingqiang , Zhuge Hai 
Published: September 2014

SummaryPeople often read with aims and reading process significantly influences understanding. This paper defines a new measure of information in text named Aimed Information Quantity in Text by simulating human reading process with reading aims. Aimed Information Quantity in Text reflects not only human memory of words but also relevancy between words emerging in aimed reading process. We demonstrate its application in recommendation. Copyright © 2014 John Wiley & Sons, Ltd.
Dialogical Exposure with Traumatically Bereaved Bosnian Women: Findings from a Controlled Trial
Authors: Hagl Maria , Powell Steve , Rosner Rita , Butollo Willi 
Published: September 2014

ObjectiveIn this trial, we compared the relative efficacy of dialogical exposure group treatment using Gestalt empty‐chair method with a supportive group in the treatment of symptoms stemming from traumatic loss in a post‐war society.MethodsOne‐hundred and nineteen women whose husbands were either killed or registered as missing during the war in Bosnia and Herzegovina were quasi‐randomized to seven sessions of group treatment with dialogical exposure or to an active control condition.ResultsBoth interventions resulted in significant improvement from baseline to post‐treatment for both kinds of loss, in terms of post‐traumatic symptoms, general mental health and grief reactions, with the exception of depression and traumatic grief in the control condition. Regarding mean effect sizes (Cohen's d), pre‐treatment to post‐treatment improvements were moderate (d = 0.56) for the dialogical exposure group and small (d = 0.34) for the supportive group. Treatment gains were maintained at least until the 1‐year follow‐up. In controlled comparisons, dialogical exposure was superior concerning traumatic grief (Cohen's d = 0.37) and post‐traumatic avoidance (d = 0.73) at post‐treatment.ConclusionsResults show that short‐term dialogical exposure group treatment was moderately effective in treating traumatically bereaved women. Copyright © 2014 John Wiley & Sons, Ltd.Key Practitioner Message

Research attests to high levels of symptoms among post‐war civil populations, in particular, when a loved one was killed, which can lead not only to trauma reactions but also to severe separation distress.
Grieving the loss of a loved one is hampered if the death remains unconfirmed.
Unconfirmed loss could be conceptualized as unfinished business in terms of Gestalt therapy, which offers empty‐chair dialogue for resolving unfinished business and grief.
Dialogical exposure therapy (DET) supports the client in gaining awareness of and expressing his or her inner dialogues concerning the traumatic event, using Gestalt empty‐chair method.
Short‐term DET was effective in treating traumatically bereaved women but showed little additional effects in comparison with a supportive group treatment, so further research is warranted.
Assessing the Utility of Bipolar Membranes for use in Photoelectrochemical Water‐Splitting Cells
Authors: Vargas‐Barbosa Nella M. , Geise Geoffrey M. , Hickner Michael A. , Mallouk Thomas E. 
Published: September 2014

AbstractMembranes are important in water‐splitting solar cells because they prevent crossover of hydrogen and oxygen. Here, bipolar membranes (BPMs) were tested as separators in water electrolysis cells. Steady‐state membrane and solution resistances, electrode overpotentials, and pH gradients were measured at current densities relevant to solar photoelectrolysis. Under forward bias conditions, electrodialysis of phosphate buffer ions creates a pH gradient across a BPM. Under reverse bias, the BPM can maintain a constant buffer pH on both sides of the cell, but a large membrane potential develops. Thus, the BPM does not present a viable solution for electrolysis in buffered electrolytes. However, the membrane potential is minimized when the anode and cathode compartments of the cell contain strongly basic and acidic electrolytes, respectively.
Ruthenium‐Catalyzed Switchable N–H/C–H Alkenylation of 6‐Phenyl(dihydro)pyridazinones with Alkynes
Authors: Wang Wei , Liang Lei , Xu Fengrong , Huang Wenjie , Niu Yan , Sun Qi , Xu Ping 
Published: September 2014

AbstractA ruthenium‐catalyzed switchable N–H/C–H alkenylation reaction of 6‐phenyl‐(dihydro)pyridazin‐3(2H)‐ones triggered by a nitrogen/oxygen atmosphere was developed. To achieve switchable modification of the two important sites of the widely used pharmacophore, a simple and efficient procedure containing two optimized ruthenium catalytic systems was utilized, which afforded excellent activity, high selectivity, and good tolerance of a wide range of functional groups.
Brønsted Acid/Lewis Acid Cooperatively Catalyzed Addition of Diazoesters to 2H‐Chromene Acetals
Authors: Luan Yi , Qi Yue , Gao Hongyi , Ma Qianqian , Schaus Scott E. 
Published: September 2014

AbstractA Brønsted acid/Lewis acid dual catalyst system was developed to promote efficient C–C bond formation between a range of oxocarbenium precursors derived from chromene acetals and ethyl diazoacetate. The reaction proceeds under mild conditions and is tolerant of functionalized 2H‐chromenes and isochromene acetals. In addition, an asymmetric variant of diazoacetate addition towards 2H‐chromene acetals is described. Continued investigations include further optimization of asymmetric induction towards the formation of diazo ester substituted 2H‐chromene.
Focusing and continuous separation of microparticles by insulator‐based dielectrophoresis (iDEP) in stair‐shaped microchannel
Authors: Cheri Mohammad Sadegh , Latifi Hamid , Khashei Hesamodin , Seresht Mohsen Jamshidi 
Published: September 2014

Focusing and separation of microparticles in a complex mixture have had wide applications in chemistry, biology, medicine, etc. This work presents a numerical and experimental investigation on focusing and continuous separation of microparticles in a geometrically optimized arrangement of steps in the form of a staircase using insulator‐based dielectrophoresis (iDEP) mechanism. First, a detailed finite element analysis was performed on important parameters in the focusing and separation of microparticles, such as geometry of stair‐shaped microchannel, total voltage, and voltage difference applied to reservoirs. The optimum parameters obtained from numerical analysis were used for experimental work. Theoretically, predicted microparticle trajectories are in good agreement with experimentally observed ones. Experimental and numerical results show that the performance of focusing of microparticles enhances with growth of the total voltage (in a constant voltage difference) and decreases with voltage difference. The fabricated iDEP microchip enhances the performance of focusing and separation of microparticles due to its stair‐shaped microchannel and therefore operates at low DC total applied voltages of 90–110 V.
Boronate affinity‐assisted MEKC separation of highly hydrophilic urinary nucleosides using imidazolium‐based ionic liquid type surfactant as pseudostationary phase
Authors: Rageh Azza H. , Pyell Ute 
Published: September 2014

In this work, we extend our investigations regarding the separation of urinary nucleosides by MEKC with the ionic liquid type surfactant 1‐tetradecyl‐3‐methylimidazolium bromide (C14MImBr). We study the impact of adding alkyl‐ and arylboronic acids (in the presence of C14MImBr micelles) to the separation of these highly hydrophilic metabolites and investigate the mechanism of interaction between the negatively charged nucleosides (the negative charge is acquired either due to deprotonation of the amidic group and/or complexation with boronate) and the positively charged pseudostationary phase. This interaction is not only due to electrostatic (Coulombic) forces, but also due to hydrophobic interaction of the alkyl or aryl group of the boronate that forms a complex with the cis‐diol group of the nucleoside. In this case, alkylboronates can act as a cosurfactant that increases the partitioning coefficient of the analytes into the micelles. In the presence of an alkylboronate in the BGE (employing only 20 mmol/L C14MImBr), the retention factors of the studied analytes are increased considerably when compared to a BGE without this additive. It is shown that the concept of one‐site hydrophobically assisted ion exchange can be applied to describe the observed retention behavior. The high selectivity of boronates toward cis‐diol‐containing compounds can be used to adjust selectively the migration behavior of members of this compound class. By adding alkylboronic acid to the BGE, the separation selectivity is fine‐tuned so that interferences from matrix components can be avoided in real sample analysis.
Shame Memories and Eating Psychopathology: The Buffering Effect of Self‐Compassion
Authors: Ferreira Cláudia , Matos Marcela , Duarte Cristiana , Pinto‐Gouveia José 
Published: September 2014

AbstractObjectiveResearch suggests that self‐compassion may protect against shame in eating disorders. This study examines the association between shame memories, self‐compassion, self‐judgment and eating psychopathology severity and tests the moderator effect of self‐compassion on the relationships between shame memories and eating psychopathology.MethodParticipants were 34 patients with the diagnosis of an eating disorder, who were assessed using Eating Disorder Examination and the Shame Experiences Interview and self‐report instruments measuring the traumatic and centrality to identity features of shame memories, self‐compassion and self‐judgment.ResultsSelf‐compassion was negatively correlated to shame memory features and eating psychopathology, and self‐judgment was positively associated with such variables. Self‐compassion had a moderator effect on the association between shame traumatic and central memories and eating psychopathology severity.ConclusionThis is the first study to explore the buffering effect of self‐compassion against the pathogenic effects of shame memories on eating psychopathology severity in eating disorders, with relevant clinical and research implications. Copyright © 2014 John Wiley & Sons, Ltd and Eating Disorders Association.
Eating Disorder Examination Questionnaire (EDE‐Q): Norms for Undergraduate Japanese Women
Authors: Nakai Yoshikatsu , Nin Kazuko , Fukushima Mitsuo , Nakamura Konoyu , Noma Shunichi , Teramukai Satoshi , Taniguchi Ataru , Wonderlich Stephen 
Published: September 2014

AbstractThe aim of the present study was to provide normative data for the Eating Disorder Examination Questionnaire (EDE‐Q) among undergraduate Japanese women and to compare these data to norms obtained from previous studies. Undergraduate Japanese women (n = 289), aged 18–24 years, were administered the EDE‐Q. The mean global score in the present study was 1.55 (SD = 1.03). Japanese women reported significantly higher scores of shape concern and weight concern in spite of lower body mass index but a significantly lower score of restraint, compared with women in other normative studies. There were significant differences with respect to the occurrence of some specific eating disorder behaviours between Japanese women and women in the previous studies. Differences in normative data for the EDE‐Q between young Japanese women and young women in the previous studies suggest that there may be certain cultural differences in eating disorder psychopathology. Copyright © 2014 John Wiley & Sons, Ltd and Eating Disorders Association.
Numerical solutions of systems with (p,δ)‐structure using local discontinuous Galerkin finite element methods
Authors: Kröner Dietmar , Růžička Michael , Toulopoulos Ioannis 
Published: September 2014

SUMMARYIn this paper, we present LDG methods for systems with (p,δ)‐structure. The unknown gradient and the nonlinear diffusivity function are introduced as auxiliary variables and the original (p,δ) system is decomposed into a first‐order system. Every equation of the produced first‐order system is discretized in the discontinuous Galerkin framework, where two different nonlinear viscous numerical fluxes are implemented. An a priori bound for a simplified problem is derived. The ODE system resulting from the LDG discretization is solved by diagonal implicit Runge–Kutta methods. The nonlinear system of algebraic equations with unknowns the intermediate solutions of the Runge–Kutta cycle is solved using Newton and Picard iterative methodology. The performance of the two nonlinear solvers is compared with simple test problems. Numerical tests concerning problems with exact solutions are performed in order to validate the theoretical spatial accuracy of the proposed method. Further, more realistic numerical examples are solved in domains with non‐smooth boundary to test the efficiency of the method. Copyright © 2014 John Wiley & Sons, Ltd.
Neurotoxic effects of ochratoxin A on the subventricular zone of adult mouse brain
Authors: Paradells Sara , Rocamonde Brenda , Llinares Cristina , Herranz‐Pérez Vicente , Jimenez Misericordia , Garcia‐Verdugo Jose Manuel , Zipancic Ivan , Soria Jose Miguel , Garcia‐Esparza Ma. Angeles 
Published: September 2014

AbstractOchratoxin A (OTA), a mycotoxin that was discovered as a secondary metabolite of the fungal speciesAspergillusandPenicillium, is a common contaminant in food and animal feed. This mycotoxin has been described as teratogenic, carcinogenic, genotoxic, immunotoxic and has been proven a potent neurotoxin. Other authors have previously reported the effects of OTA in different structures of the central nervous system as well as in some neurogenic regions. However, the impact of OTA exposure in the subventricular zone (SVZ) has not been assessed yet. To elucidate whether OTA affects neural precursors of the mouse SVZ we investigated,in vitroandin vivo, the effects of OTA exposure on the SVZ and on the neural precursors obtained from this neurogenic niche. In this work, we prove the cumulative effect of OTA exposure on proliferation, differentiation and depletion of neural stem cells cultured from the SVZ. In addition, we corroborated these resultsin vivoby immunohistochemistry and electron microscopy. As a result, we found a significant alteration in the proliferation process, which was evidenced by a decrease in the number of 5‐bromo‐2‐deoxyuridine‐positive cells and glial cells, as well as, a significant decrease in the number of neuroblasts in the SVZ. To summarize, in this study we demonstrate how OTA could be a threat to the developing and the adult SVZ through its impact in cell viability, proliferation and differentiation in a dose‐dependent manner. Copyright © 2014 John Wiley & Sons, Ltd.
Exploring the Sequence Context of Phosphorylatable Amino Acids: The Contribution of the Upgraded MAPRes Tool
Authors: Iqbal Zeeshan , Hoessli Daniel C. , Qazi Wajahat M. , Ahmad Munir , Shakoori Abdul Rauf , Nasir‐ud‐Din  
Published: September 2014

ABSTRACTSeveral models that predict where post‐translational modifications are likely to occur and formulate the corresponding association rules are available to analyze the functional potential of a protein sequence, but an algorithm incorporating the functional groups of the involved amino acids in the sequence analyses process is not yet available. In its previous version, MAPRes was utilized to investigate the influence of the surrounding amino acids of post‐ translationally and co‐translationally modifiable sites. The MAPRes has been upgraded to take into account the different biophysical and biochemical properties of the amino acids that have the potential to influence different post‐ translational modifications (PTMs). In the present study, the upgraded version of MAPRes was implemented on phosphorylated Ser/Thr/Tyr data by considering the polarity and charge of the surrounding amino acids. The patterns mined by MAPRes incorporating structural information on polarity and charge of amino acids suggest distinct structure‐function relationships for phosphorylated serines in a multifunctional protein such as the insulin‐receptor substrate‐1 (IRS‐1) protein. The new version of MAPRes is freely available at http://www.imsb.edu.pk/Database.htm. J. Cell. Biochem. 116: 370–379, 2015. © 2014 Wiley Periodicals, Inc.
Microscopic observations of self‐healing products in calcareous fly ash mortars
Authors: Jóźwiak‐Niedźwiedzka Daria 
Published: September 2014

ABSTRACTThe results of microstructural characterization of mortars containing fly ash class C (High Calcium Fly Ash) from combustion of lignite are presented. The evaluation of the microstructure was performed using scanning electron microscope, optical, and confocal microscope. The tested beams were bent till the crack and microcracks opening, which were healed during the different curing time. The results showed that the replacement of cement with fly ash class C influenced the process of crack healing. The addition of HCFA, at both 30% and 60%, speeds up the self‐healing process in cracks and particularly in micro‐cracks. In the research, the completely filling up of the cracks by new phases has not been observed, only the beginning of such process has been noticed. Microsc. Res. Tech., 78:22–29, 2015. © 2014 Wiley Periodicals, Inc.
A Characterization of Mixed Unit Interval Graphs
Authors: Joos Felix 
Published: September 2014

AbstractWe give a complete characterization of mixed unit interval graphs, the intersection graphs of closed, open, and half‐open unit intervals of the real line. This is a proper superclass of the well‐known unit interval graphs. Our result solves a problem posed by Dourado, Le, Protti, Rautenbach, and Szwarcfiter (Mixed unit interval graphs, Discrete Math 312, 3357–3363 (2012)).
Labelling of ceftriaxone with 99mTc and its bio‐evaluation as an infection imaging agent
Authors: Sohaib Muhammad , Khurshid Zain , Roohi Samina 
Published: September 2014

AbstractDifferentiation of bacterial and sterile inflammation will have a significant impact on the current clinical practice. Ceftriaxone (CTRX) was labelled with 99mTc and assessed for its ability to depict infection on scintigraphy. Stoichiometry was performed to optimize labelling parameters. Stability and bacterial binding was verified and biodistribution pattern was seen in normal, infected/inflamed animal models. 99mTc‐CTRX prepared at pH 7 with stannous chloride of 50 µg, ligand of 30 mg, and boiling for 10 min gave labelling yield of 96.2 ± 0.2% with good stability. In vitro binding was higher for Escherichia coli than Staphylococcus aureus. Biodistribution in normal rats showed high uptake in hepatobiliary system, gut and urinary system. In animal models induced with infection or inflammation, lesion to normal ratios at 4 h were 2.36 ± 0.21, 12.66 ± 1.44 and 1.40 ± 0.01 with S. aureus infection, E. coli infection and turpentine oil inflammation, respectively. Infection specificity especially for E. coli was also confirmed on scintigraphic findings.Ceftriaxone can be labelled with 99mTc with high labelling yield at pH compatible with that of blood. Our preparation has shown stability in vitro and in human serum, and binds preferentially with bacteria. 99mTc‐CTRX scintigraphy can be used to delineate sites of active infection and to differentiate infection and inflammation.
Self‐Assembly of Conjugated Units Using Metal‐Terpyridine Coordination
Authors: Gao Yang , Rajwar Deepa , Grimsdale Andrew C. 
Published: September 2014

Due to their inherently dynamic natures and fascinating photoluminescent/photoelectronic properties, coordination compounds of metal ions and conjugated terpyridine ligands have attracted considerable attention as functional materials for a variety of potential applications. In this feature article, a summary of recent work toward the development of one‐ (1D), two‐ (2D), and three‐dimensional (3D) supramolecular polymers, networks, and metallomacrocycles based on zinc metal ion coordination of conjugated units bearing terpyridine ligands is presented, and it is shown how it fits within the overall framework of work in this field. Here, a sequential study from terpyridines as basic building blocks to their zinc‐coordinated supramolecular 1D polymers, 2D macrocycles, and 2D and 3D networks is developed. These networks are compared with respect to their thermal stabilities, molecular organization, and linear and nonlinear optical properties. This work opens new prospects for the development of supramolecular chemistry of terpyridines and other transition metal ions, and also their application in future optoelectronic devices.
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Performance of a Bis(imine)Pyridine Iron Catalyst System in Ethylene/Norbornene Copolymerization with Zinc Diethyl
Authors: Pereira Leticia Quinello , de Fatima Vieira Marques Maria 
Published: September 2014

SummaryBrookhart catalysts are widely used in ethylene polymerization to produce polymers with high molecular weight and crystallinity degree. In the present work, the performance of a bis(imine)pyridine iron catalyst and methylaluminoxane (MAO) as a catalytic system was evaluated for ethylene/norbornene copolymerization and the influence of adding zinc diethyl (DEZ) in the reaction medium was investigated. The results showed that the system was effective in copolymerization besides the low incorporation of norbornene in polymer chain, as indicated by multimodal profiles in DSC and high crystalline degree.