bluuebunny/crossref_metadata_2025_split huggingface dataset:
L'introduction du « vol relatif » dans le parachutisme sportif des années 1970 – 1980 : reconfiguration ou « contre-culture » ?
Authors: Loirand Gildas 
Published: January 2013

Résumé Fondé sur l’étude empirique de l’introduction du « vol relatif » comme nouvelle modalité « fun » du parachutisme sportif dans les années soixante-dix, cet article se propose de montrer que le travail d’enquête permet d’offrir des ressources compréhensives et explicatives qui font souvent très largement défaut dans la plupart des études consacrées aux transformations des pratiques sportives à partir du postulat peu discuté selon lequel le moteur du changement serait essentiellement « contre-culturel ». Il entend ainsi souligner les limites des descriptions globales du changement en insistant sur le fait que, s’il y a bien interpénétration et importation culturelles en matière de parachutisme, les transformations que celles-ci génèrent s’opèrent finalement dans des espaces spécifiques pré-structurés qu’on ne saurait ignorer pour espérer lire et interpréter sociologiquement les ruptures et/ou les continuités. D’un point de vue analytique, le texte tend à manifester que si « contre-culture » sportive il y a eu dans les années soixante-dix et quatre-vingt, celle-ci devrait être précisément rapportée, en chaque cas, à ceux qui la revendiquent comme aux contextes sportifs singuliers dans lesquels elle s’exprime et y exerce des effets.
La reconversion paradoxale des sportifs français : Premiers enseignements d'une enquête sur les sélectionnés aux jeux olympiques de 1972 et 1992
Authors: Fleuriel Sébastien , Schotté Manuel 
Published: January 2013

Résumé Ce texte, tiré d’une enquête par questionnaires et par entretiens, porte sur la reconversion de sélectionnés olympiques français. Après avoir questionné la façon dont on peut, penser la reconversion en sociologie, ce travail met en évidence un paradoxe : si les enquêtés accèdent à des positions majoritairement situées dans le haut de l’espace social, celles-ci restent la plupart du temps ancrées dans l’espace sportif, produisant alors un effet d’enfermement. Outre la faible convertibilité du capital sportif, l’article montre aussi que l’ascension objective n’est linéaire qu’en apparence dans la mesure où la reconversion professionnelle est souvent vécue comme un déclassement par rapport à la position sportive antérieurement occupée.
Ranibizumab Versus Photodynamic Therapy for Presumed Ocular Histoplasmosis Syndrome
Authors: Ramaiya Kamalesh J. , Blinder Kevin J. , Ciulla Thomas , Cooper Blake , Shah Gaurav K. 
Published: January 2013

BACKGROUND AND OBJECTIVE:
To evaluate the efficacy of ranibizumab in the treatment of choroidal neovascularization secondary to presumed ocular histoplasmosis syndrome.

PATIENTS AND METHODS:
Patients enrolled in the ranibizumab group received a monthly intravitreal injection of 0.5 mg of ranibizumab. Patients in the photodynamic therapy (PDT) group received a quarterly dosing of intravenous verteporfin coupled with PDT.

RESULTS:
Mean change in ETDRS visual acuity at 1 year was 19.6 letters in the ranibizumab group versus 21 letters in the PDT group. All patients in the PDT group required rescue ranibizumab therapy. Four of five patients (80%) in the ranibizumab group and one of two patients (50%) in the PDT group showed a greater than 15 letter gain at 1 year.

CONCLUSION:
Ranibizumab appears to be a safe and effective treatment option for choroidal neovascularization secondary to the presumed ocular histoplasmosis syndrome.
Pediatric Retinal Conditions Imaged by Ultra Wide Field Fluorescein Angiography
Authors: Tsui Irena , Franco-Cardenas Valentina , Hubschman Jean-Pierre , Schwartz Steven D. 
Published: January 2013

BACKGROUND AND OBJECTIVE:
Ultra wide field technology was originally designed for use in children. The purpose of this study was to evaluate ultra wide field fluorescein angiography (UWFFA) in children.

PATIENTS AND METHODS:
Retrospective case series of patients younger than 13 years who underwent UWFFA. Angiographic findings and their impact on diagnosis and management were assessed. UWFFA quality was evaluated, including phases of the angiogram available in each study, field of view, and artifacts.

RESULTS:
Forty images of 16 patients with a mean age of 9.3 years were included. Peripheral angiographic findings such as vasculitis, telangiectasia, and neovascularization were present in 12 of 16 patients (75%). Seven of 16 patients (43.8%) had images during the arterial phase, and 16 of 16 patients (100%) had venous and recirculation phases captured.

CONCLUSION:
UWFFA was successfully performed in this group of children. The macula and periphery were adequately imaged, obtaining important information for documentation, diagnosis, and management.
Developing a Tool to Assess the Quality of Socio-Demographic Data in Community Health Centres
Authors: Shachak A. , Laberge M. 
Published: January 2013

SummaryObjective: The objectives of this study are to 1) create a quality assessment tool for socio-demographic data aligned with the needs of Community Health Centres (CHCs) and based on the data quality framework of the Canadian Institute for Health Information (CIHI), and 2) test the feasibility of the tool in CHCs.Methods: The tool was developed based on both theoretical and practical knowledge. A review of the literature was performed to identify data quality frameworks and dimensions that could be employed. In addition, informal discussions with Community Health Centres staff members holding various positions were conducted and a team of subject matter experts was established. This approach supported the alignment between the tool (i.e., the indicators developed, the rating scale, and weighting system) and the setting for which it has been designed. The tool was pilot tested in five CHCs across Ontario.Results: The decision to focus on socio-demographic data was based on findings from the discussions with staff members. The team established nine principles for the development of the tool, including the use of computer software, whenever possible, to query the data and ensure consistency of the measurement. Data quality scores ranged from 45 to 74 on a scale of 0 (lowest quality) to 100 (highest data quality), with one CHC that was not able to run all of the queries. The feedback from staff was positive and supports the feasibility of the tool as an application of the CIHI data quality framework in a local setting.Conclusion: Pilot test results demonstrate the feasibility of the tool and an applicability of the CIHI framework as a basis for developing tools for data quality assessment in health care organizations.Citation: Laberge M, Shachak A. Developing a tool to assess the quality of socio-demographic data in community health centres. Appl Clin Inf 2012; 4:1–11http://dx.doi.org/10.4338/ACI-2012-10-CR-0041
Morphometric Study of the Jugular Foramen in Northwest Indian Population
Authors: Aggarwal Anjali , Gupta Tulika , Kaur Harjeet , Singla Anjali , Sahni Daisy 
Published: January 2013

ABSTRACT

Context
Most of the approaches for skull base surgeries are designed to drill the bone around the jugular foramen for proper exposure. In order to achieve this, an understanding of normal morphometric dimensions of jugular foramen is necessary.

Aim
To conduct the morphometric analysis and anatomical variations of jugular foramen (JF) in Northwest Indian population.

Settings and design
Anatomic study using human skulls.

Materials and methods
Anteroposterior and mediolateral diameter of jugular foramen, depth (if domed) and width of jugular fossa were measured with the help of digital vernier caliper.

Statistical analysis used
The mean, standard deviation (SD) and range of each dimension was computed. A comparison between right and left jugular foramina was made by using student's t-test.

Results
Mediolateral diameter of jugular foramen and width of jugular fossa was significantly higher on the right side. An abnormal unilateral blockage of jugular foramen by a bone growth converting it into a slit was noted with anteroposterior (AP) diameter of 2.37 mm in one skull. Bilateral complete septation of jugular foramen into two and three compartments was observed in 2 (4%) and 3 (6%) of the skulls respectively. The domed bony roof was noticed in 66% of the skulls on both the sides.

Conclusion
The observed variations of JF are possibly due to constitutional, racial or genetic factors. Knowledge of the observed variations of this foramen may be important for neurosurgeons, radiologists and anthropologists.

Key message
The total subdivision of jugular foramen is not common in our environment. The jugular foramen is generally larger on right side. This study supports reported morphometric variations of jugular foramen, besides adding data on the Northwest Indian population.

Abbreviation
CC: carotid canal; BO: basi-occiput; OC: occipital condyle; JF: jugular foramen; S: styloid process.

How to cite this article
Singla A, Sahni D, Aggarwal A, Gupta T, Kaur H. Morphometric Study of the Jugular Foramen in Northwest Indian Population. J Postgrad Med Edu Res 2012;46(4):165-171.
A Comparative Analysis of the Efficacy and Safety of fixed Combinations of Latanoprost/Timolol vs Dorzolamide/Timolol in Primary Open Angle Glaucoma or Ocular Hypertension
Authors: Ratol Sukhsagar , Walia Rani , Chaudhry Mridu 
Published: January 2013

ABSTRACT

Background
Glaucoma is a leading cause of irreversible blindness. The fundamental problem in medical management of glaucoma is of patient compliance. An ideal drug or a drug combination is needed to slow the progression of this majorly symptomless disease.

Aim
To compare the efficacy and tolerability of the fixed combination latanoprost and timolol instilled once daily in the evening vs fixed combination of dorzolamide and timolol instilled twice daily in primary open angle glaucoma or ocular hypertension.

Materials and methods
A 12-week, randomized, open, parallel group study including 50 patients with primary open angle glaucoma or ocular hypertension was conducted at a tertiary care hospital. Patients were randomized to group 1, (fixed combination (FC) latanoprost and timolol eye drops, once daily in evening) and group 2, (FC dorzolamide and timolol eye drops, twice daily). At baseline, 2, 4 and 12 weeks, IOP was recorded at 9 AM and 12 noon. The difference in IOP reduction in two treatment groups from baseline to 12 weeks was the main outcome measure.

Results
Mean diurnal IOP was similar at baseline for both groups. Mean reduction in IOP from baseline to 12 weeks was 9.92 mm Hg (p = 0.001) in group 1 and 9.22 (p = 0.001) in group 2. The reduction in IOP in both groups 1 and 2 was statistically significant at all time intervals. There was a statistically significant advantage for group 1 at 12 weeks for both time readings (p = 0.013 and 0.002 respectively) as compared to group 2.

Conclusion
The fixed combination of latanoprost and timolol was more effective than that of dorzolamide and timolol in reducing mean diurnal IOP and both treatments were well tolerated. To confirm further such studies are required.

How to cite this article
Ratol S, Walia R, Chaudhry M. A Comparative Analysis of the Efficacy and Safety of fixed Combinations of Latanoprost/Timolol vs Dorzolamide/Timolol in Primary Open Angle Glaucoma or Ocular Hypertension. J Postgrad Med Edu Res 2012;46(4):172-176.
Clinical Implications of Thermoplastic Mask Immobilization on Acute Effects of Radiotherapy in Head and Neck Cancers
Authors: Bahl Amit , Sharma Suresh C , Ghosal Sushmita , Kapoor Rakesh , Bhattacharya Tapesh 
Published: January 2013

ABSTRACT

Aim
Thermoplastic immobilization devices are used in head and neck radiotherapy to increase precision of treatment delivery. However, there is concern about increase in radiation induced skin morbidity with the use of such devices. This study was conducted with an aim to evaluate any increase in clinically observed skin reactions with the use of thermoplastic immobilization devices.

Materials and methods
Fifty patients of head and neck cancers undergoing radical radiotherapy were randomized into two study groups in this prospective randomized study. Group ‘A’ received treatment with thermoplastic immobilization device. Group ‘B’ received treatment without any immobilization device. A weekly assessment of normal tissue reactions was done using Radiation Therapy Oncology Group (RTOG) acute radiation acute radiation morbidity scoring criteria.

Results
Increase in skin reactions was seen in patients using thermoplastic devices. Grade 3 reactions were seen in 56 vs 52% in the study and control group respectively. The difference was however not statistically significant (p = 0.09).

Conclusion
Increase in skin dose with use of thermoplastic immobilization devices may not clinically translate into a significant increase in acute skin reactions. Thermoplastic immobilization devices can be safely used in head and neck cancers to ensure accurate radiation delivery.

How to cite this article
Bahl A, Ghosal S, Kapoor R, Bhattacharya T, Sharma SC. Clinical Implications of Thermoplastic Mask Immobilization on Acute Effects of Radiotherapy in Head and Neck Cancers. J Postgrad Med Edu Res 2012;46(4):187-189.
Multiple Vertebral Hemangiomas Mimicking Metastases in a Patient with Renal Carcinoma: Importance of Hybrid Imaging with SPECT/CT and FDG PET/CT
Authors: Mittal BR , Bhattacharya A , Manohar K , Parghane RVR , Kumari S , Mandal AK 
Published: January 2013

ABSTRACT
Vertebral hemangiomas are the most common benign tumors of the spine and usually present as cold defects on skeletal scintigraphy. However, these lesions may rarely show uptake of Tc-99m methylene diphosphonate, mimicking metastases. In this patient with renal carcinoma, abnormal vertebral tracer uptake (indicative of skeletal metastases on planar bone scintigraphy) was subsequently localized to vertebral lesions identified as hemangiomas on the CT component of single photon emission computed tomography/computed tomography (SPECT/CT). None of these hemangiomas showed any uptake of F-18 fluorodeoxyglucose on positron emission tomography/ computed tomography (PET/CT).

How to cite this article
Manohar K, Parghane RVR, Kumari S, Bhattacharya A, Mandal AK, Mittal BR. Multiple Vertebral Hemangiomas Mimicking Metastases in a Patient with Rena Carcinoma: Importance of Hybrid Imaging with SPECT/CT and FDG PET/CT. J Postgrad Med Edu Res 2012;46(4):196-197.
Utility of F-18 Fluorothymidine PET Over F-18 Fluorodeoxyglucose PET/CT in Detection of a Recurrent Glioma
Authors: Gupta Vivek , Bhattacharya Anish , Kashyap Raghava , Tiwari Manoj Kumar , Senthil Raja , Mittal Bhagwant Rai 
Published: January 2013

ABSTRACT
Differentiation of postsurgical or postradiation necrosis from tumor recurrence is a clinical dilemma. Magnetic resonance imaging does not always perform well in this setting. Several nuclear medicine techniques are available that offer a solution in such a clinical situation. We report a case where F-18 flurodeoxyglucose (FDG) and F-18 fluorothymidine (FLT) PET/CT were used to identify recurrence of a glioma.

How to cite this article
Kashyap R, Tiwari MK, Senthil R, Bhattacharya A, Gupta V, Mittal BR. Utility of F-18 Fluorothymidine PET Over F-18 Fluorodeoxyglucose PET/CT in Detection of a Recurrent Glioma. J Postgrad Med Edu Res 2012;46(4):202-203.
The Expression of Egfl7 in Human Normal Tissues and Epithelial Tumors
Authors: Fan Chun , Yang Lian-Yue , Wu Fan , Tao Yi-Ming , Liu Lin-Sen , Zhang Jin-Fan , He Ya-Ning , Tang Li-Li , Chen Guo-Dong , Guo Lei 
Published: January 2013

Background and aims To investigate the expression of Egfl7 in normal adult human tissues and human epithelial tumors. Methods RT-PCR and Western blot were employed to detect Egfl7 expression in normal adult human tissues and 10 human epithelial tumors including hepatocellular carcinoma (HCC), lung cancer, breast cancer, prostate cancer, colorectal cancer, gastric cancer, esophageal cancer, malignant glioma, ovarian cancer and renal cancer. Immunohistochemistry and cytoimmunofluorescence were subsequently used to determine the localization of Egfl7 in human epithelial tumor tissues and cell lines. ELISA was also carried out to examine the serum Egfl7 levels in cancer patients. In addition, correlations between Egfl7 expression and clinicopathological features as well as prognosis of HCC and breast cancer were also analyzed on the basis of immunohistochemistry results. Results Egfl7 was differentially expressed in 19 adult human normal tissues and was overexpressed in all 10 human epithelial tumor tissues. The serum Egfl7 level was also significantly elevated in cancer patients. The increased Egfl7 expression in HCC correlated with vein invasion, absence of capsule formation, multiple tumor nodes and poor prognosis. Similarly, upregulation of Egfl7 in breast cancer correlated strongly with TNM stage, lymphatic metastasis, estrogen receptor positivity, Her2 positivity and poor prognosis. Conclusions Egfl7 is significantly upregulated in human epithelial tumor tissues, suggesting Egfl7 to be a potential biomarker for human epithelial tumors, especially HCC and breast cancer.
The Ethics of the Imperative
Authors: Ednie‐Brown Pia 
Published: January 2013

AbstractThe bald desire to innovate is not sufficient in itself. To go beyond mere technical invention and make a positive difference, innovation requires an engagement with overall ethical intent. Here, Guest‐Editor Pia Ednie‐Brown espouses a design ethos that values an open‐ended approach to architectural innovation. She illustrates the ethical impact of implementing new technologies with two opposing paradigms – one dark and one affirmative – as exemplified by two classic films from 1968: 2001: A Space Odyssey and Barbarella.
Innovation at the Storefront: The Practice of Eva Franch I Gilabert
Authors: Ednie‐Brown Pia 
Published: January 2013

AbstractAn event and exhibition space opening on to the sidewalk of New York City's SoHo, Storefront is dedicated to the advancement of innovative positions in architecture and design. It seeks ‘to simultaneously shake and question the current state of affairs’. Guest‐Editor Pia Ednie‐Brown discusses with the Catalan architect, Eva Franch i Gilabert, her role as Director of Storefront, and specifically how she has promoted active, generative engagement through humour, disruption and innovation.
Becoming Architectural: Affirmative Critique, Creative Incompletion
Authors: Massumi Brian 
Published: January 2013

AbstractWhen Greg Lynn embraced digital animation software in the 1990s, he not only redefined architectural production, but also the designer's relationship to the generative process. In this extract from an unpublished essay written in 2000, the philosopher Brian Massumi describes Lynn's ‘in‐folding’ open‐ended approach, which renders the design process ‘less an external conduit for the artist's creativity’ than the artist ‘a conduit for creativity of the design process’.
bioMASON and the Speculative Engagements of Biotechnical Architecture
Authors: Ednie‐Brown Pia 
Published: January 2013

AbstractIn the last decade, biotechnical architecture has become one of the most fertile areas for speculative architecture. Guest‐Editor Pia Ednie‐Brown traces the recent lineage of this field, highlighting the work of Ginger Krieg Dosier and Michael Dosier of Vergelabs, which has pushed biotechnical architecture further towards actualisation; their company bioMASON specialises in the biomanufacture of building material and its architectural applications.
Final Draft: Designing Architecture's Endgame
Authors: Wilkins Gretchen , Burrow Andrew 
Published: January 2013

Abstract‘Completion is both essential for, and antithetical to, innovation.’ Here, Gretchen Wilkins and Guest‐Editor Andrew Burrow attempt to resolve this generative paradox by going in search of ‘open‐to‐ending strategies in architectural practice’. They advocate the model of the ‘final draft’ in the design process as a means to bringing a project to a close while anticipating or encouraging future work.
Architecture, Innovation and Tradition
Authors: Picon Antoine 
Published: January 2013

AbstractAntoine Picon, Professor of the History of Architecture and Technology at Harvard Graduate School of Design (GSD), and the author of a significant new book, Ornament: The Politics of Architecture and Subjectivity (John Wiley & Sons), publishing in April 2013, provides the counterargument to this issue. He argues that for innovation to go beyond the superficial level of being a mere design trend or fashion, it needs to avoid ‘presentism’ and develop a reflexive stance to history and tradition.
Label‐Free Electrical Detection of DNA Hybridization on Graphene using Hall Effect Measurements: Revisiting the Sensing Mechanism
Authors: Lin Cheng‐Te , Loan Phan Thi Kim , Chen Tzu‐Yin , Liu Keng‐Ku , Chen Chang‐Hsiao , Wei Kung‐Hwa , Li Lain‐Jong 
Published: January 2013

AbstractThere is broad interest in using graphene or graphene oxide sheets as a transducer for label‐free and selective electrical detection of biomolecules such as DNA. However, it is still not well explored how the DNA molecules interact with and influence the properties of graphene during the detection. Here, Hall effect measurements based on the Van der Pauw method are used to perform single‐base sequence selective detection of DNA on graphene sheets, which are prepared by chemical vapor deposition. The sheet resistance increases and the mobility decreases with the addition of either complementary or one‐base mismatched DNA to the graphene device. The hole carrier concentration of the graphene devices increases significantly with the addition of complementary DNA but it is less affected by the one‐base mismatched DNA. It is concluded that the increase in hole carrier density, indicating p‐doping to graphene, is better correlated with the DNA hybridization compared to the commonly used parameters such as conductivity change. The different electrical observations of p‐doping from Hall effect measurements and n‐doping from electrolyte‐gated transistors can be explained by the characteristic morphology of partially hybridized DNA on graphene and the mismatch between DNA chain length and Debye length in electrolytes.
Secondary Photocrosslinking of Injectable Shear‐Thinning Dock‐and‐Lock Hydrogels
Authors: Lu Hoang D. , Soranno Danielle E. , Rodell Christopher B. , Kim Iris L. , Burdick Jason A. 
Published: January 2013

AbstractShear‐thinning hydrogels are useful in numerous applications, including as injectable carriers that act as scaffolds to support cell and drug therapies. Here, we describe the engineering of a self‐assembling Dock‐and‐Lock (DnL) system that forms injectable shear‐thinning hydrogels using molecular recognition interactions that also possess photo‐triggerable secondary crosslinks. These DnL hydrogels are fabricated from peptide‐modified hyaluronic acid (HA) and polypeptide precursors, can self‐heal immediately after shear induced flow, are cytocompatible, and can be stabilized through light‐initiated radical polymerization of methacrylate functional groups to tune gel mechanics and erosion kinetics. Secondary crosslinked hydrogels retain self‐adhesive properties and exhibit cooperative physical and chemical crosslinks with moduli as high as ∼10 times larger than moduli of gels based on physical crosslinking alone. The extent of reaction and change in properties are dependent on whether the methacrylate is incorporated either at the terminus of the peptide or directly to the HA backbone. Additionally, the gel erosion can be monitored through an incorporated fluorophore and physical–chemical gels remain intact in solution over months, whereas physical gels that are not covalently crosslinked erode completely within days. Mesenchymal stem cells exhibit increased viability when cultured in physical– chemical gels, compared with those cultured in gels based on physical crosslinks alone. The physical properties of these DnL gels may be additionally tuned by adjusting component compositions, which allows DnL gels with a wide range of physical properties to be constructed for use.