bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ankle Arthroplasty in Patients Younger and Older than 50 Years: A Prospective Series with Long-term Follow-up
Authors: Kofoed Hakon , Lundberg-Jensen Allan 
Published: March 2013

One hundred consecutive cases treated with ankle arthroplasty for osteoarthritis (OA) or rheumatoid arthritis were followed prospectively and annually for up to 15 years. Survivorship analysis was performed, with the endpoint being prosthesis revision or change to arthrodesis. Patients who were younger than 50 years at the first implantation constituted one group (group A, 30 ankles). The other group (group B, 70 ankles) consisted of patients aged 50 years or older at the first implantation. All patients were assessed clinically according to the Kofoed Ankle Score. The distribution of OA/rheumatoid arthritis in group A was 18/12, and in group B it was 43/27 (not significant). The median age in group A was 46 years (range, 22–49 years), and in group B it was 63 years (range, 51–83 years). In group A, one case was revised, and three cases were converted to arthrodesis after a median of 5 years (range, 5–9 years). In group B, four cases were revised, and four cases were converted to arthrodesis after a median of 5.5 years (range, 2–8 years). The results of cases with traumatic OA did not differ between groups A and B. It was concluded that the results of ankle arthroplasty were of equal quality in patients younger than 50 years and those who were older.
Peroneus Quartus Muscle: A Case Report and Review of the Literature
Authors: Trono Marco , Tueche Serge , Quintart Christian , Libotte Mark , Baillon JeanMarie 
Published: March 2013

The peroneus quartus is a supernumerary muscle of the lateral compartment of the lower leg. There are several variations of this accessory muscle, and its terminology is very confusing. The peroneus quartus is found with a frequency varying from 10 to 21.7% of observed individuals. 4 , 17 It is rarely involved in pathologic processes of the foot and ankle. Only a few reports exist in the literature involving peroneus quartus in a “retromalleolar conflict” (lateral ankle stenosis 17 ), sometimes in association with longitudinal attrition and tears of the peroneus brevis. We present a novel case, together with a review of the clinical, anatomic, and radiologic references about this muscle, and we try to make order in classification and terminology of its different forms.
Arthroscopy of the Ankle: Analysis of Results and Indications on a Series of 75 Cases
Authors: Bonnin Michel , Bouysset Maurice 
Published: March 2013

The purpose of this study was to evaluate the results of arthroscopy of the ankle. Of the 114 arthroscopies of the ankle that we performed between 1991 and 1996, 13 were for diagnosis, 6 were associated with open surgery, and 10 were ankle arthrodeses. We report the results of the remaining 85 therapeutic arthroscopies. We identified five groups according to preoperative indications: (1) anterolateral synovitis after a sprained ankle (33 cases), (2) sequelae of fractured ankles (17 cases), (3) anterior impingement as a result of osteophytes (12 cases), (4) loose foreign bodies as a result of avulsion of fragments of bone (6 cases), and (5) osteochondral lesions of the talar dome (17 cases). In anterolateral synovitis, results were better when the pain followed a single sprain than when after chronic instability. In osteochondral lesions of the talar dome, results were better in anterolateral lesions than in posteromedial lesions.
Effect of Increasing Distal Medial Closing Wedge Metatarsal Osteotomies on the Distal Metatarsal Articular Angle
Authors: Lau Johnny T.C. , Daniels Timothy R. 
Published: March 2013

The recognition, definition, and management of the congruent hallux valgus deformity continue to evolve. To correct the skeletal deformity and maintain joint congruity, many authors have emphasized the importance of extra-articular procedures. One such procedure is a distal medial closing wedge osteotomy of the first metatarsal. Unfortunately, there are few guidelines to help determine the pre- and intraoperative size of the medial wedge to obtain the desired correction of the distal metatarsal articular angle (DMAA). The purpose of this study was to quantify the effects of increasing distal medial closing wedge osteotomies on the DMAA in an in vitro cadaver model. In this study, a closing wedge osteotomy was performed 2 cm proximal to the articular surface, removing wedges measuring 2 mm, 4 mm, and 6 mm in width. The mean preoperative DMAA was 8.5°, and the mean postoperative DMAAs after 2-mm, 4-mm, and 6-mm closing wedge osteotomies were −2.6°, −10.2°, and −20.2°, respectively. The data showed that for every 1 mm of closing wedge osteotomy, the DMAA decreased by 4.7° ± 0.6°. These results can be used for pre- and intraoperative planning when surgically correcting a congruent hallux valgus deformity with a distal medial closing wedge osteotomy of the first metatarsal. Additional information obtained from this cadaver study includes (1) increased shortening of the first metatarsal and (2) incongruity produced at the joint after the medial-based osteotomy. The amount of shortening of the first metatarsal correlated directly with the size of the medial-based wedge. The second point indicates that a lateral soft-tissue release may still be required when using this method of reorienting the DMAA.
Plantar Fasciitis: How Successful Is Surgical Intervention?
Authors: Davies Mark S. , Weiss Galen A. , Saxby Terence S. 
Published: March 2013

Forty-three patients (47 heels) underwent decompression of the nerve to abductor digiti minimi with partial plantar fascia release for intractable plantar fasciitis over a 4-year period. Forty-one patients (45 heels) were available for follow-up. All of the patients had failed to respond to nonoperative treatment. The mean duration of symptoms before surgery was 34.8 months (range, 12–132 months), and the mean follow-up was 31.4 months (range, 11–66 months). Seventy percent of the patients in the study were overweight or obese. Before surgery, 39 patients (43 heels) rated their heel pain as severe. At follow-up, 34 of 45 (75.6%) of the heels were pain-free or only mildly painful. The mean visual analogue pain score dropped from 8.5 of 10 preoperatively to 2.5 of 10 postoperatively. Only four patients failed to report an improvement in their activity restrictions, and only one patient had a walking distance of under 100 m after surgery; this patient had been affected by a reflex sympathetic dystrophy. Overall, however, only 20 of 41 patients were totally satisfied with the outcome (48.8%). We recommend that the small group of patients who fail to respond to nonoperative treatment be considered for surgical intervention. The results in terms of symptomatic relief are generally good but in terms of patient satisfaction can only be rated as moderate. The patients should be counseled about the likely outcome of surgery.
Clarification of status of species in the pyrochlore supergroup
Authors: Christy A. G. , Atencio D. 
Published: March 2013

AbstractAfter careful consideration of the semantics of status categories for mineral species names, minor corrections and disambiguations are presented for a recent report on the nomenclature of the pyrochlore supergroup. The names betafite, elsmoreite, microlite, pyrochlore and roméite are allocated as group names within the pyrochlore supergroup. The status of the names bindheimite, bismutostibiconite, jixianite, monimolite, partzite, stetefeldtite and stibiconite is changed from 'discredited' to 'questionable' pending further research.
On the symmetry and crystal structure of aguilarite, Ag4SeS
Authors: Bindi L. , Pingitore N. E. 
Published: March 2013

AbstractAn examination of a specimen of aguilarite from the type locality provides new data on the chemistry and structure of this mineral. The chemical formula of the crystal used for the structural study is (Ag3.98 Cu0.02)(Se0.98 S0.84 Te0.18), on the basis of 6 atoms. The mineral was found to be monoclinic, crystallizing in space group P 21/n, with a = 4.2478(2), b = 6.9432(3), c = 8.0042(5) Å , β = 100.103(2)º, V = 232.41(2) Å3 and Z = 4. The crystal structure [refined to R1 = 0.0139 for 958 reflections with I > 2 σ (I)] is topologically identical to that of acanthite, Ag2S. It can be described as a body-centred array of tetrahedrally coordinated X atoms (X = S, Se and Te) with Ag2X3 triangles in planes nearly parallel to (010); the sheets are linked by the Ag1 silver site, which has twofold coordination.Aguilarite is definitively proved to be isostructural with acanthite; it does not have a naumannite-like structure, as previously supposed. Our data support the hypothesis that there are two solid solution series in the system: a monoclinic 'acanthite-like' series (from Ag2S - Ag2S0.4Se0.6), and an orthorhombic 'naumannite-like' series (from Ag2S0.3Se0.7-Ag2Se). This is supported by data gathered on synthetic counterparts. Aguilarite remains as a valid as a mineral species, but it should be described as the Se-analogue of acanthite.In this study we also (1) review the history of the aguilarite; (2) compare properties of synthetic and natural aguilarite; and (3) demonstrate how earlier researchers erred in describing aguilarite as orthorhombic.The Te-bearing composition of the studied aguilarite crystal suggests the possibility of a solid solution with cervelleite (Ag4TeS).
Cerchiaraite-(Fe) and cerchiaraite-(Al), two new barium cyclosilicate chlorides from Italy and California, USA
Authors: Kampf A. R. , Roberts A. C. , Venance K. E. , Carbone C. , Belmonte D. , Dunning G. E. , Walstrom R. E. 
Published: March 2013

AbstractThe ideal formula for members of the cerchiaraite group is Ba4M4(Si4O12)O2(OH)4Cl2[Si2O3(OH)4], where M represents Mn3+, Fe3+ or Al in the octahedral site. A suffix-based naming scheme is used in which the original cerchiaraite is renamed cerchiaraite-(Mn) and two new minerals are named cerchiaraite-(Fe) and cerchiaraite-(Al). The type localities for cerchiaraite-(Fe) are the Cerchiara mine, Liguria, Italy and the Esquire No. 7 and No. 8 claims, Big Creek, Fresno County, California, USA. The type localities for cerchiaraite-(Al) are the Esquire No. 1 claim, Rush Creek, Fresno County, California, USA and the Esquire No. 7 and No. 8 claims noted above. At the Cerchiara mine, cerchiaraite-(Fe) occurs in small fractures and veinlets in a Jurassic ophiolitic sequence. It is of secondary hydrothermal origin and occurs as tan to brown thin prisms and matted fibres. Cerchiaraite(Fe) and cerchiaraite-(Al) from the Esquire No. 1, No. 7 and No. 8 claims occur in parallel-bedded quartz-sanbornite vein assemblages which formed as a result of fluid interaction along the margin of the vein. At the Esquire No. 1, No. 7 and No. 8 claims, both cerchiaraite-(Fe) and cerchiaraite-(Al) occur as subparallel aggregates of blue to bluish green irregular prisms. Both minerals are transparent with a vitreous lustre, Mohs hardness ~4½ , brittle tenacity, irregular fracture and no cleavage. The calculated density of cerchiaraite-(Fe) is 3.710 g cm-3; the measured density of cerchiaraite-(Al) is 3.69(3) g cm-3and the calculated density is 3.643 g cm-3. Cerchiaraite-(Fe) is uniaxial (+), with ω = 1.741(2) and ε = 1.768(2); it is weakly pleochroic and O is colourless and E is yellow. Cerchiaraite-(Al) is uniaxial (-), with ω = 1.695(2) and e = 1.677(2); it is strongly pleochroic and O is colourless and E is blue. Electron-microprobe analyses yielded empirical formulae ranging from (Ba3.82Na0.02Ca0.04)Σ3.88(Fe3+3.42Ti4+0.27Al3+0.25Mn3+0.04Mg0.02)Σ4.00Si5.62O15.47(OH)9.31Cl2.22 (Cerchiara mine) to Ba4.00(Al3+2.40Fe3+1.12Mg0.15Fe2+0.12Mn2+0.06)Σ3.85Si5.78O15.34(OH)8.75Cl2.91 (Esquire No. 1 claim). Cerchiaraite is tetragonal with Z = 2 and crystallizes in space group I4/mmm. The cell parameters for cerchiaraite-(Fe) are a = 14.3554(12), c = 6.0065(5) Å and V = 1237.80(5) Å3; those for cerchiaraite(Al) are a = 14.317(4), c = 6.0037(18) Å and V = 1230.6(6) Å3. In the cerchiaraite-(Fe) structure, SiO4 tetrahedra share corners forming a four-membered Si4O12 ring. The ring is corner-linked to an edgesharing chain of Fe3+ O6 octahedra running parallel to c. A Cl site alternates along c with the Si4 O12 ring. A large channel in the framework contains Ba atoms around its periphery and statistically distributed Si2 O7 silicate dimers and Cl atoms. The strong blue pleochroic colour is attributed to Fe2+ - Fe3+intervalence charge transfer along the octahedral chain.
Yaroshevskite, Cu9O2(VO4)4Cl2, a new mineral from the Tolbachik volcano, Kamchatka, Russia
Authors: Pekov I. V. , Zubkova N. V. , Zelenski M. E. , Yapaskurt V. O. , Polekhovsky Yu. S. , Fadeeva O. A. , Pushcharovsky D. Yu. 
Published: March 2013

AbstractA new mineral, yaroshevskite, ideally Cu9O2(VO4)4Cl2, occurs in sublimates collected from the Yadovitaya fumarole at the Second scoria cone of the Northern Breakthrough of the Great Tolbachik Fissure Eruption, Tolbachik volcano, Kamchatka, Russia. It is associated with euchlorine, fedotovite, hematite, tenorite, lyonsite, melanothallite, atlasovite, kamchatkite and secondary avdoninite, belloite and chalcanthite. Yaroshevskite forms isolated prismatic crystals, up to 0.1 × 0.15 × 0.3 mm in size, on the surface of euchlorine crusts. The mineral is opaque and black, with a reddish black streak and lustre between metallic and adamantine. Yaroshevskite is brittle, no cleavage was observed and the fracture is uneven. The Mohs hardness is ~3½ (corresponding to a mean VHN micro-indentation hardness of 172 kg mm -2) and the calculated density is 4.26 g cm-3. In reflected light, yaroshevskite is grey with a weak bluish hue. Pleochroism, internal reflections and bireflectance were not observed. Anisotropy is very weak. The composition (wt.%) determined by electron microprobe is: CuO 61.82, ZnO 0.53, Fe2O30.04, V2O531.07, As2O50.32, MoO31.56, Cl 6.23, O=Cl21.41; total 100.16. The empirical formula, calculated on the basis of 20 (O + Cl) anions is (Cu8.80Zn0.07Fe0.01)Σ 8.88(V3.87Mo0.12As0.03)σ 4.02O18.01Cl1.99. Yaroshevskite is triclinic, space groupP,a= 6.4344(11),b= 8.3232(13),c= 9.1726(16) Å , α = 105.338(14), β = 96.113(14), γ = 107.642(1)°,V= 442.05(13) Å3andZ= 1. The nine strongest reflections in the X-ray powder pattern [dobs in Å (I)(hkl)] are as follows: 8.65(100)(001); 6.84(83)(01); 6.01(75)(100); 5.52(60)(01); 4.965(55)(011); 4.198(67)(1); 4.055(65)(110); 3.120(55)(021); 2.896(60)(21,003,20). The crystal structure was solved by direct methods from single-crystal X-ray diffraction data and refined toR= 0.0737. The yaroshevskite structure is unique. It is based on corrugated layers made up of chains of edge-sharing flat squares with central Cu2+cations [Cu(1), Cu(4) and Cu(5)]; neighbouring chains are connected via groups consisting of three Cu2+-centred squares [two Cu(3) and Cu(6)]. Neighbouring layers are connected via pairs of Cu(2)O4Cl five-coordinate polyhedra and isolated VO4tetrahedra. The structure of yaroshevskite can also be considered in terms of oxygen-centred tetrahedra: O(7)Cu4tetrahedra are connected via common Cu(4) and Cu(5) vertices to form pyroxene-like chains [O2Cu6]∞. In this context, the structural formula can be written Cu3[O2Cu6][VO4]4Cl2. The mineral name honours the Russian geochemist Alexei A. Yaroshevsky (b. 1934) of Moscow State University.
FcγRIII (CD16) equips immature 6-sulfo LacNAc–expressing dendritic cells (slanDCs) with a unique capacity to handle IgG-complexed antigens
Authors: Döbel Thomas , Kunze Anja , Babatz Jana , Tränkner Katja , Ludwig Andreas , Schmitz Marc , Enk Alexander , Schäkel Knut 
Published: March 2013

Key PointsThe expression of CD16 by immature slanDCs equips these cells with a unique capacity to handle immune complexes. CD16 expression on slanDCs is rapidly downregulated during maturation by activation of ADAM10 and ADAM17.
Comparative analysis of circulating dendritic cell subsets in patients with atopic diseases and sarcoidosis
Authors: Hayashi Yumeko , Ishii Yoshiki , Hata-Suzuki Mitsumi , Arai Ryo , Chibana Kazuyuki , Takemasa Akihiro , Fukuda Takeshi 
Published: March 2013

AbstractBackgroundDendritic cells (DCs) are professional antigen-presenting cells that play a crucial role in the initiation and modulation of immune responses. Human circulating blood DCs are divided into two major subsets: myeloid DCs (mDCs); and plasmacytoid DCs (pDCs). Furthermore, mDCs are subdivided into two subsets: Th1-promoting mDCs (mDC1s); and Th2-promoting mDCs (mDC2s). Although CD1a, CD1c, and CD141 are generally used for classifying mDC subsets, their adequacy as a specific marker remains unclear. We performed this study to compare circulating mDC, pDC, mDC1, and mDC2 subsets between Th1- and Th2-mediated diseases using CD1a and CD141, and to analyze the adequacy of CD1a and CD141 as a marker for mDC1s and mDC2s, respectively.MethodsThirty patients with sarcoidosis, 23 patients with atopic diseases, such as atopic bronchial asthma, and 23 healthy subjects as controls were enrolled in this study. Peripheral blood DC subsets were analyzed with flow cytometry according to expressions of CD11c, CD123, CD1a, and CD141. For functional analysis, we measured interleukin (IL) 12p40 levels produced by the sorted mDC subsets.ResultsThe sarcoidosis group showed decreased total DC (P < 0.05) and mDC counts (P < 0.05) compared to controls. The atopy group showed decreased CD1a+mDC count (P < 0.05), and increased CD1a-mDC count (P < 0.05) compared to controls. CD141+mDC count in the atopy group was higher than controls (P < 0.05). Sorted CD1a+mDCs produced higher levels of IL-12p40 than CD1a-mDCs (P = 0.025) and CD141+mDCs (P = 0.018).ConclusionsWe conclude that decreased count of CD1a+mDC and increased count of CD141+mDC may reflect the Th2-skewed immunity in atopic diseases. The results of IL-12 levels produced by the sorted mDC subsets suggested the adequacy of CD1a and CD141 as a marker for mDC1 and mDC2, respectively,in vivo.
Genetic variants associated with circulating MMP1 levels near matrix metalloproteinase genes on chromosome 11q21-22 in Taiwanese: interaction with obesity
Authors: Huang Hsuan-Li , Wu Semon , Hsu Lung-An , Teng Ming-Sheng , Lin Jeng-Feng , Sun Yu-Chen , Ko Yu-Lin 
Published: March 2013

AbstractBackgroundMMP1 is implicated in the pathogenesis of atherothrombotic cardiovascular disease. We aimed to elucidate genetic determinants of inflammatory marker levels, including circulating MMP1, in Taiwanese, and their association with obesity.MethodsFive genetic polymorphisms around matrix metalloproteinase genes on chromosome 11q21-22 region were genotyped in 519 subjects.ResultsAfter adjusting for clinical covariates, two polymorphisms were significantly associated with MMP1 levels, rs1799750 and rs495366, using an additive inheritance model (P = 1.5x10-4andP = 2.57x10-5, respectively). Using dominant model, minor alleles of rs1799750 and rs495366 were associated with higher MMP1 levels (P = 1.3x10-4andP = 1.95x10-5, respectively). In haplotype analysis, two haplotypes inferred from five SNPs (A2GATAandA1GATG) were associated with MMP1 levels (P = 5x10-4andP = 8.47x10-5, respectively). Subgroup and interaction analysis revealed an association of rs1799750 and rs495366 with MMP1 levels only in non-obese subjects (P = 6.66x10-6andP = 4.38x10-5, respectively, and interactionP = 0.008 for rs1799750). Haplotype interaction analysis also showed significant interaction for haplotypeA1GATG(interactionP = 0.003).ConclusionsGenotypes/haplotypes aroundMMP1locus are associated with MMP1 levels in Taiwanese. Further, since genotypes/haplotypes nearMMP1locus interact with obesity to set MMP1 levels, genetic determinants for MMP1 level may be different between obese and non-obese individuals.
Negative pressure technology enhances bone regeneration in rabbit skull defects
Authors: Zhang Yin-gang , Yang Zhi , Zhang Hong , Liu Miao , Qiu Yushen , Guo Xiong 
Published: March 2013

Abstract

Background
Bone is a slowly regenerating tissue influenced by various physiological processes, including proliferation, differentiation, and angiogenesis, under the control of growth factors. Shortening this healing time is an important and popular clinical research focus in orthopedics. Negative pressure can stimulate angiogenesis, improve blood circulation, promote granulation tissue growth and accelerate tissue wound healing. We sought to determine whether negative pressure could reduce bone healing time in a rabbit cranial defect model.

Methods
Four symmetrical holes (diameter, 3.5 mm) were drilled into the skulls of 42 New Zealand white rabbits, with two holes in each parietal bone. For each rabbit, the two sides were then randomly assigned into experimental and control groups. Using negative pressure suction tubes, experimental holes were treated with −50 kPa for 15 minutes, four times per day, whereas the control holes remained untreated. After 4 weeks, the negative pressure suction tubes were removed. At 2, 4, 6 and 8 weeks, three-dimensional (3D) reconstruction computed tomography (CT), X-ray radiopacity, and two-photon absorptiometry were used to evaluate new bone formation. Histological changes were determined by hematoxylin and eosin (H.E) staining. At weekly intervals until 6 weeks, the mRNA expression levels of vascular endothelial growth factor (VEGF) and bone morphogenetic protein (BMP)-2 were evaluated by RT-PCR. A paired student’s t-test was employed to compare X-ray radiopacity and bone density measurements between the experimental and control groups.

Results
3D-reconstruction CT showed that new bone regeneration in the experimental group was greater than that in the control group at 4 and 6 weeks. At these time points, the experimental group presented with higher X-ray radiopacity and increased bone density (P < 0.05) as compared with the control group. Cartilage islands and new bone were observed by H.E staining at 2 weeks in the experimental group. By 6 weeks, the new bone had matured into lamellar bone in the experimental group. RT-PCR results showed that VEGF and BMP-2 were highly expressed in the experimental group as compared with control.

Conclusions
Intermittent negative pressure can promote the regeneration of bone possibly by enhancing the expression of VEGF and BMP-2.
Development of a cost-effective high-throughput process of microsatellite analysis involving miniaturized multiplexed PCR amplification and automated allele identification
Authors: Nguyen Truc TM , Lakhan Shaheen E , Finette Barry A 
Published: March 2013

Abstract

Background
Microsatellites are nucleotide sequences of tandem repeats occurring throughout the genome, which have been widely used in genetic linkage analysis, studies of loss of heterozygosity, determination of lineage and clonality, and the measurement of genome instability or the emergence of drug resistance reflective of mismatch repair deficiency. Such analyses may involve the parallel evaluation of many microsatellite loci, which are often limited by sample DNA, are labor intensive, and require large data processing.

Results
To overcome these challenges, we developed a cost-effective high-throughput approach of microsatellite analysis, in which the amplifications of microsatellites are performed in miniaturized, multiplexed polymerase chain reaction (PCR) adaptable to 96 or 384 well plates, and accurate automated allele identification has been optimized with a collective reference dataset of 5,508 alleles using the GeneMapper software.

Conclusions
In this investigation, we have documented our experience with the optimization of multiplex PCR conditions and automated allele identification, and have generated a unique body of data that provide a starting point for a cost-effective, high-throughput process of microsatellite analysis using the studied markers.