bluuebunny/crossref_metadata_2025_split huggingface dataset:
Diagnostic value of neutrophil gelatinase-associated lipocalin, cystatin C, and soluble triggering receptor expressed on myeloid cells-1 in critically ill patients with sepsis-associated acute kidney injury
Authors: Dai Xingui , Zeng Zhenhua , Fu Chunlai , Zhang Sheng’an , Cai Yeping , Chen Zhongqing 
Published: May 2015

Abstract
Introduction
Neutrophil gelatinase-associated lipocalin (NGAL), cystatin C (Cys-C), and soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) are novel diagnostic biomarkers of acute kidney injury (AKI). We aimed to determine the diagnostic properties of these biomarkers for detecting AKI in critically ill patients with sepsis.

Methods
We divided 112 patients with sepsis into non-AKI sepsis (n = 57) and AKI sepsis (n = 55) groups. Plasma and urine specimens were collected on admission and every 24 hours until 72 hours and tested for NGAL, Cys-C, and TREM-1 concentrations. Their levels were compared on admission, at diagnosis, and 24 hours before diagnosis.

Results
Both plasma and urine NGAL, Cys-C, and sTREM-1 were significantly associated with AKI development in patients with sepsis, even after adjustment for confounders by using generalized estimating equations. Compared with the non-AKI sepsis group, the sepsis AKI group exhibited markedly higher levels of these biomarkers at diagnosis and 24 hours before AKI diagnosis (P <0.01). The diagnostic and predictive values of plasma and urine NGAL were good, and those of plasma and urine Cys-C and sTREM-1 were fair.

Conclusion
Plasma and urine NGAL, Cys-C, and sTREM-1 can be used as diagnostic and predictive biomarkers for AKI in critically ill patients with sepsis.
Does the gender composition of forest and fishery management groups affect resource governance and conservation outcomes: a systematic map protocol
Authors: Leisher Craig , Temsah Gheda , Booker Francesca , Day Michael , Agarwal Bina , Matthews Elizabeth , Roe Dilys , Russell Diane , Samberg Leah , Sunderland Terry , Wilkie David 
Published: May 2015

Abstract
Background
In the fields of environmental governance and biodiversity conservation, there is a growing awareness that gender has an influence on resource use and management. Several studies argue that empowering women in resource governance can lead to beneficial outcomes for resource sustainability and biodiversity conservation. Yet how robust is the evidence to support this claim? Here we focus on the forestry and fisheries sectors to answer the primary question: What is the evidence that the gender composition of forest and fishery management groups affects resource governance and conservation outcomes? Our objective is to produce a systematic map of the evidence highlighting, inter alia, the geographic distribution and quality of the evidence, the consistency and robustness of the findings, and where further research is needed.

Methods/design
This protocol provides the details of the methodology. The search terms used to identify relevant articles were developed in an iterative process using the phraseology of the primary question, Boolean operators, and a list of synonyms for each term. The search terms will be used to identify relevant articles in CAB Abstracts, Scopus, AGRIS, AGRICOLA, Google Scholar, and Google. A test library of 12 articles will ensure that the search captures the relevant literature. Searches will be in English but will not be restricted by publication date. The websites of 22 international organisations with a known interest in gender-related issues will be screened for relevant documents. The gender-focussed researchers at large conservation NGOs, the members of the Poverty and Conservation Learning Group, and the members of the Gender and Environment Working Group will be invited to submit relevant documents. The list of references of included articles will be screened to identify other relevant articles in a ‘backwards snowballing’ approach. The inclusion criteria are that an article refers to women or gender, forests or fisheries, a resource management group, a quantitative comparison, and an environmental governance or biodiversity conservation outcome in a non-OECD country. A data extraction template with 27 variables will be used to assess the included articles. The output will be a narrative report with descriptive statistics and an evidence-gap map.
Genetic variants and risk of gastric cancer: a pathway analysis of a genome-wide association study
Authors: Lee Ju-Han , Kim Younghye , Choi Jung-Woo , Kim Young-Sik 
Published: May 2015

Abstract
This study aimed to discover candidate single nucleotide polymorphisms (SNPs) for hypothesizing significant biological pathways of gastric cancer (GC). We performed an Identify Candidate Causal SNPs and Pathways (ICSNPathway) analysis using a GC genome-wide association study (GWAS) dataset, including 472,342 SNPs in 2,240 GC cases and 3,302 controls of Asian ethnicity. By integrating linkage disequilibrium analysis, functional SNP annotation, and pathway-based analysis, seven candidate SNPs, four genes and 12 pathways were selected. The ICSNPathway analysis produced 4 hypothetical mechanisms of GC: (1) rs4745 and rs12904 → EFNA1 → ephrin receptor binding; (2) rs1801019 → UMPS → drug and pyrimidine metabolism; (3) rs364897 → GBA → cyanoamino acid metabolism; and (4) rs11187870, rs2274223, and rs3765524 → PLCE1 → lipid biosynthetic process, regulation of cell growth, and cation homeostasis. This pathway analysis using GWAS dataset suggests that the 4 hypothetical biological mechanisms might contribute to GC susceptibility.
Predictors of life satisfaction among Asian American adolescents- analysis of add health data
Authors: Huang Jui-Yen , Wang Kuan-Yuan , Ringel-Kulka Tamar 
Published: May 2015

AbstractLife satisfaction correlates with adolescent risk taking behavior and their outcomes in adulthood. Despite the fast rise in numbers of Asian adolescents in the U.S., the predictors of their life satisfaction are not well understood. This study examined the relationship between several demographic and contextual factors and global life satisfaction among this population. Data were derived from the National Longitudinal Study of Adolescent Health (Add Health), a nationally representative probability sample of US adolescents. Bivariate and multivariable logistic regression was conducted to evaluate hypothesized predictors of global life satisfaction of Asian American adolescents. All analyses were conducted using STATA version 11. After exclusion of cases with missing values, 1021 Asian American adolescents were studied. Self- rated health, self-esteem, perceived neighborhood quality, parental support and peer support were significantly and positively related to better global life satisfaction. However, after controlling for other factors, only self-esteem (adjusted odds ratio [aOR]: 4.76; 95% confidence interval [CI]: 2.86-8.33) and perceived peer support (aOR: 2.76; 95% CI: 1.33-5.76) significantly predicted higher life satisfaction. Peer support and adolescents’ self-concept are strongly correlated with Asian American adolescents’ subjective well-being. To promote the wellness of this population, culturally sensitive strategies in developing peer relationship and healthy self-concept may be effective. More studies are needed for subgroup comparison of various ethnicities among Asian American adolescents.
International Pediatric Non-Hodgkin Lymphoma Response Criteria
Authors: Sandlund John T. , Guillerman R. Paul , Perkins Sherrie L. , Pinkerton C. Ross , Rosolen Angelo , Patte Catherine , Reiter Alfred , Cairo Mitchell S. 
Published: May 2015

Purpose Response criteria are well established for adult patients with non-Hodgkin lymphoma (NHL). A revised set of response criteria in adults with NHL was recently published. However, NHL in children and adolescents involves different histologies, primary sites of disease, patterns of metastatic spread, approaches to therapy, and responses to treatment compared with adult NHL. However, there are no standardized response criteria specific to pediatric NHL. Therefore, we developed international standardized methods for assessing response to therapy in children and adolescents with NHL. Methods An international multidisciplinary group of pediatric oncologists, pathologists, biologists, and radiologists convened during and after the Third and Fourth International Childhood, Adolescent and Young Adult NHL Symposia to review existing response and outcome data, develop methods for response evaluation that reflect incorporation of more sensitive technologies currently in use, and incorporate primary and metastatic sites of disease for the evaluation of therapeutic response in children and adolescents with NHL. Results Using the current adult NHL response criteria as a starting point, international pediatric NHL response criteria were developed incorporating both contemporary diagnostic imaging and pathology techniques, including novel molecular and flow cytometric technologies used for the determination of minimal residual disease. Conclusion Use of the international pediatric NHL response criteria in children and adolescents receiving therapy for NHL incorporates data obtained from new and more sensitive technologies that are now being widely used for disease evaluation, providing a standardized means for reporting treatment response.
800 - Morphological analysis of gutta-percha points subjected to different treatments and influence on obturation sealing
Authors: Rosa Patrícia Campos Ferreira da , Oliveira Simone Helena Gonçalves de , Vasconcelos Rafaela Andrade de 
Published: May 2015

Objective: This study evaluated the morphological changes in scanning electron microscopy (SEM), which occur on the surface of gutta-percha points at times exceeded those recommended. Methods: 2% chlorhexidine (CLX), 2.5% sodium hypochlorite (NaOCl), 2%peracetic acid (PA) and 0.25% peracetic acid (SAP) solutions were used in periods of 1 minute, 30 minutes, 6 hours and 12 hours. Groups were divided according to the solution and disinfection period (n=12). Results: The results indicated that there was statistically significant difference between the solutions and periods tested. In 1 minute, all solutions do not differ from the control. After 30 minutes, the SAP significantly alter the morphology of the points. The test energy dispersive spectrometry (EDS) indicated that all the solution periods alter the chemical composition of gutta-percha points. The relationship of disinfection on microleakage of filling was also evaluated in groups that suffered disinfection for 12 hours. The SAP group showed statistically significant difference compared to control, because 100% of its roots showed infiltration. The other groups of CLX, NaOCl and AP, although not statistically significant, were respectively 9, 8 and 8 out of 12 of his roots with infiltration. Conclusion: Concluded that the disinfection process can cause morphological changes if the immersion period is exceeded and that, in addition to altering the chemical composition of gutta-percha, these solutions can influence the sealing of the filling.
Effect of thermal treatment on the bending strength of glass ceramic/resin cement
Authors: Saavedra Guilherme Siqueira Ferreira Anzaloni , Pedrique Beatriz , Cavalheiro Rodrigo Furtado , Borges Alexandre Luiz Souto , Paes-Junior Tarcisio José de Arruda 
Published: May 2015

Objectives: To investigate the effect of the thermal treatment on the bending strength of ceramic bars (VM7) treated by the cementation protocol. Material and Methods: Forty ceramic bars (20 x 4 x 1.2 mm) were constructed and randomly distributed into 2 groups (n=20): NT - without treatment/control and T – with treatment (50°C above the glass transition temperature, for 15 min). All specimens underwent the cementation process in which one surface of the ceramic bar was etched (20 s) with 10% hydrofluoridric acid, followed by air-water jet washing (60 s), drying (30 s), silane agent application and resin cementation. After storage (distilled water/seven days at 37 ºC), the specimens were submitted to 3-point flexure test at 100% humidity/37 ºC (v=1 mm/min, load cell of 10 kgf). Results: The bending strength values and standard deviations (MPa) were: NT: 19.98 (3.17)a; T: 20.45 (4.67)a (one-way ANOVA and Tukey test, ?=0.05). Conclusions: The thermal treatment did not influence on the bending strength mean values of the ceramics studied.
Treatment Considerations for Patient with amelogenesis imperfecta: a review
Authors: Chen Chiung-Fen , Hu Jan CC , Bresciani Eduardo , Peters Mathilde C , Estrella Maria Regina P 
Published: May 2015

Objectives: Amelogenesis imperfecta (AI) is a group of inherited disorders primary affecting the structural of enamel. Patients with AI experience poor esthetic excessive tooth sensitivity and compromised chewing function that dental treatments are frequently required at early age. This review describes the nonenamel implications, stage-specific management strategies and outcomes of selected restorative materials based on literature evidence.Keywords Amelogenesis imperfecta; Dental enamel, abnormalities; Dentistry, operative.
Prevalence of dental anomalies in children analyzed by orthopantomography
Authors: Cunha Monise Garcia Moreira , Di Nicollo Rebeca , Teramoto Lucia , Fava Marcelo 
Published: May 2015

Objective: To determine the prevalence of dentalanomalies in patients aged from 4-12 years-oldthrough radiographic examination. Materialand Methods: 523 panoramic radiographs andfile records were selected and analyzed by 3calibrated examiners. The material was selectedfrom the Orthodontic and Pediatric Dentistry filesof Child Clinics of the Science and TechnologyInstitute of Sao Jose dos Campos of the Sao PauloState University, including only those with highquality and contrast. Data were submitted tostatistical analysis. Results: The tabulated datawere statistically analyzed by Mann Whitneytest and Fisher’s exact test. There was a higherincidence of abnormalities in females (56.72%).It was found 7 cases (1.34%) of supernumeraryteeth, 47 cases (8.99%) of anodontia, 45 cases(8.60%) of impacted teeth, 28 cases (5.35%) ofdilacerated teeth, and 7 cases (1.34%) of ankyloseddeciduous teeth. Conclusion: According to thesample studied, dental anomalies were presentin 25.62% of the children. Considering thenumber of supernumerary, ankylosed, impactedand dilacerated teeth, there were no statisticaldifferences between genders. There was statisticaldifference between genders regarding to thenumber of anodontia, with higher predominancein females.KeywordsDental anomalies; Children; Deciduous teeth; Panoramic radiograph.
Evaluation of 0.5% peracetic acid and 2.5% sodium hypochlorite on smear layer removal of root canal instrumented by three rotary systems
Authors: Gomes Ana Paula Martins , Lissi Lais dos Santos , Coelho Marcella Batista Pavanello , Da Silva Eduardo Galera , Martinho Frederico Canato , Huhtala Maria Filomena Rocha Lima 
Published: May 2015

Objective: The aim of this study was to evaluate the effect of 0.5% peracetic acid solution and 2.5% sodium hypochlorite solution on smear layer removal of root canal walls after rotary instrumentation. Material and methods: Sixty single-rooted human teeth with standardized length had their canals instrumented by three rotary systems (Biorace, MTwo and Endowave), varying the irrigation solution, as follows (n=10): G1- Biorace System + 0.5% peracetic acid solution; G2- Biorace System + 2.5% sodium hypochlorite solution; G3- MTwo System + 0.5% peracetic acid solution; G4- MTwo System + 2.5% sodium hypochlorite solution; G5- Endowave System + 0.5% peracetic acid solution; G6- Endowave System + 2.5% sodium hypochlorite solution. After instrumentation, the roots were cleaved and the dentin walls were evaluated by SEM at x500 and x2000 magnification for assessing the cleaning of the root canals at the cervical, middle and apical thirds. The analyzed area was quantified according to the total number of tubules present and the percentage of open tubules at each region. Data were submitted to statistical analysis by ANOVA and Tukey tests, at the significance level of 5%. Results: There were no statistical significant differences among the experimental groups. In all groups the smear layer removal at cervical and medium thirds was higher than that of apical third. Conclusion: It was concluded that the cleaning obtained at the apical third was lower in all groups studiedand neither the instrumentation technique nor the irrigating solution was able to promote total smear layer removal from root canal walls. KEYWORDS: Peracetic acid; Root canal irrigants; Scanning electron microscopy; Sodium hypochlorite.
Innovative Strategies in the Public Administration: Report of the Experience at the School of Dentistry (Institute of Science and Technology) - Universidade Estadual Paulista “Julio de Mesquita Fillho” – UNESP, Campus of São José dos Campos
Authors: Rodrigues José Roberto , Tajra Sanmya Feitosa , Bellini Angela de Brito 
Published: May 2015

O artigo tem por objetivo apresentar o processo de mudança organizacional que está em fase de implantação na instituição pública do ensino superior, Faculdade de Odontologia de São José dos Campos – UNESP,Campus de São José dos Campos. Para promover esta mudançafoi desenvolvido o Planejamento Estratégico, inicialmente utilizando-se o modelo tradicional desta ferramenta. Posteriormenteas estratégias foram alinhadas às perspectivas de um Balanced Scorecard adaptado às necessidades dos objetivos estratégicos desta organização pública (sucesso do aluno no mercado, aprendizado e crescimento, infraestrutura de trabalho e governança institucional). Para promover a revisão estratégica e a criação de estratégias de inovação foi utilizada a metodologia da Matriz das Quatro Ações, visando identificar valores a agregar à instituição por meio do diagnóstico previsto nesta ferramenta, que facilita o levantamento dos fatores a serem elevados, eliminados, reduzidos e criados. Todo esse processo foi estabelecido conjuntamente com o desenvolvimento das lideranças de cada setor da instituição, por meio de treinamentos, sessões coaching individual e coletivo e mapeamento dos processos críticos das áreas estratégicas desta IES (Instituição de Ensino Superior).
The finite element methods on oral rehabilitation: New trend for endodontically treated teeth
Authors: Oliveira Juliana Santos , Gomes Érica Alves , Chaves Carolina de Andrade Lima , Silva Sousa Yara T. Côrrea 
Published: May 2015

The aim of this study is to present the applicability of Finite element analysis (FEA) in oral rehabilitation, especially in endodontically treated teeth, based on its indication, methods, advantages and limitations through a literature review. The search was conducted on National Library of Medicine’s Pub Med, Google search and Science Direct databases including the keywords “finite element analysis”, “oral rehabilitation” and “endodontics”. A total of 412 articles were found, 42 were carefully selected by two subject matter experts for discussion including 21 articles focusing on the applicability of FEA to endodontically treated teeth. The FEA is a versatile, low-cost and efficient approach for reliable evaluation of complex structures, as oral rehabilitation treatments. Keywords: Endodontics; Finite element analysis; Oral rehabilitation.
Culture and molecular analysis of Enterococcus faecalis and antimicrobial susceptibility of clinical isolates from patients with failure endodontic treatment
Authors: Endo Marcos Sergio , Signoretti Fernanda Graziela Corrêa , Kitayama Vivian Sayuri , Marinho Ariane Cássia Salustiano , Martinho Frederico Canato , Gomes Brenda Paula Figueiredo de Almeida 
Published: May 2015

Objective: The aim of this study was to evaluate the minimal inhibitory concentrations (MIC) of different antibiotic agents against to the most prevalent microorganism found in root-filled canals by culture and molecular approaches. Material and Methods: The microbial samples were taken either from thirty root-filled canals after removal of gutta-percha. Culture methods and 16s rDNA assay were used to identify the E faecails present in the samples. The antimicrobial susceptibilities of the isolates of E faecalis were determined by MIC values using the E test System and interpreted according to the Clinical and Laboratory Standards Institute guidelines. The following antibiotics were used: benzylpenicillin, amoxicillin, amoxicillin-clavulanic acid, erythromycin, azithromycin, vancomycin, chloramphenicol, tetracycline, doxycycline, ciprofloxacin, rifampicin and moxifloxacin. Results: E faecalis were isolated (7/30) and detected (13/30) by culture and PCR assay, respectively. All tested E faecalis (n=12) were highly sensitive to amoxicillin, moxifloxacin, vancomycin, benzylpenicillin and amoxicillin-clavulanic acid. Some antibiotics were resistant against E faecalis strains such as rifampicin (4/12), tetracycline (2/12), doxycycline (1/12), erythromycin (3/12) and azythromycin (8/12). Conclusion: Amoxicillin, amoxicillin-clavulanic acid, benzylpenicillin, vancomycin and moxifloxacin were the most active antibiotics, in vitro, against E faecalis clinical strains, with all the isolates being susceptible. Azithromycin and erythromycin were least effective, with none percentage of isolates being susceptible, during laboratory testing. Moreover, E faecalis were identified more frequently by PCR assay than by culture technique.Keywords: Retreatment; Antibiotics, antimicrobial susceptibility; Enterococcus faecalis; Antibiotic resistance.
Evaluation of the Location of Mandibular Foramen as an Anatomic Landmark Using CBCT Images: A Pioneering Study in an Iranian Population
Authors: Shokri Abbas , Falah-Kooshki Sepideh , Poorolajal Jalal , Karimi Atena , Ostovarrad Farzaneh 
Published: May 2015

Objective: Mandibular foramen (MF) is located on the internal surface of the ramus through which blood vessels and nerves pass. Determination of the anatomic position of the MF is very important in inferior alveolar nerve block anesthesia (IANBA), ramus osteotomy and surgical procedures of the posterior angle of mandibular ramus. The aim of this study was to determine anatomic position of the MF using anatomic landmarks on the three dimensional CBCT images. Material and Methods: A total of 103 CBCT images was evaluated. The NNT Viewer software program was used to measure the distances between the lines tangent on the MF periphery and the anterior border of the ramus, the posterior border of the ramus, the inferior border of the mandible, and the coronoid notch in mm by to age and gender. Results: The results showed a slight difference in anatomic dimensions between the right and left sides, with no significant differences. The anatomic dimensions of the MF on both sides were a little bigger in males than in females. There were no significant differences in the anatomic dimensions of superior-inferior and anterior-posterior dimensions of the left and right sides in different age groups. Conclusion: No significant changes occur in the position of the MF with age. The anatomic differences between males and females should be taken into account during IANBA procedures. Males have bigger jaws than females; therefore, there is a longer distance between the MF and the anatomic landmarks evaluated. Keywords: Mandibular Foramen; Anatomic Landmarks; Cone-Beam Computed Tomography