bluuebunny/crossref_metadata_2025_split huggingface dataset:
Frontal operculum gliomas: language outcome following resection
Authors: Rolston John D. , Englot Dario J. , Benet Arnau , Li Jing , Cha Soonmee , Berger Mitchel S. 
Published: January 2015

OBJECT
The dominant hemisphere frontal operculum may contain critical speech and language pathways, and due to these properties, patients with tumors of the opercular region may be at higher risk for postoperative speech dysfunction. However, the likelihood of incurring temporary or permanent language dysfunction is unknown.

METHODS
The authors retrospectively analyzed their cohort of patients with frontal gliomas to identify those tumors that predominantly involved the dominant frontal operculum. Each tumor was classified as involving the pars orbitalis, pars triangularis, pars opercularis, or a combination of some or all of these areas. The authors then identified and compared characteristics between those patients experiencing transient or permanent speech deficits, as opposed to those with no language dysfunction.

RESULTS
Forty-three patients were identified for inclusion in this analysis. Transient deficits occurred in 12 patients (27.9%), while 4 patients (9.8%) had persistent deficits involving language. Individuals with preoperative language deficits and patients with seizures characterized by speech dysfunction appear to be at the highest risk to develop a deficit (relative risks 3.09 and 1.75, respectively). No patient with a tumor involving the pars orbitalis experienced a persistent deficit.

CONCLUSIONS
Resection of gliomas is widely recognized as a critical element of improved outcome. Given the low rate of language morbidity reported in this group of patients, resection of gliomas within the dominant frontal operculum is well-tolerated with acceptable morbidity and, in this particular location, should not be a deterrent in the overall management of these tumors.
The influence of decompressive craniectomy for major stroke on early cerebral perfusion
Authors: Slotty Philipp Jörg , Kamp Marcel Alexander , Beez Thomas , Beenen Henrieke , Steiger Hans-Jakob , Turowski Bernd , Hänggi Daniel 
Published: January 2015

OBJECT
Multiple trials have shown improved survival and functional outcome in patients treated with decompressive craniectomy (DC) for brain swelling following major stroke. It has been assumed that decompression induces an improvement in cerebral perfusion. This observational study directly measured cerebral perfusion before and after decompression.

METHODS
Sixteen patients were prospectively examined with perfusion CT within 6 hours prior to surgery and 12 hours after surgery. Preoperative and postoperative perfusion measurements were compared and correlated.

RESULTS
Following DC there was a significant increase in cerebral blood flow in all measured territories and additionally an increase in cerebral blood volume in the penumbra (p = 0.03). These changes spread as far as the contralateral hemisphere. No significant changes in mean transit time or Tmax (time-to-peak residue function) were observed.

CONCLUSIONS
The presurgical perfusion abnormalities likely reflected local pressure-induced hypoperfusion with impaired autoregulation. The improvement in perfusion after decompression implied an increase in perfusion pressure, likely linked to partial restoration of autoregulation. The increase in perfusion that was observed might partially be responsible for improved clinical outcome following decompressive surgery for major stroke. The predictive value of perfusion CT on outcome needs to be evaluated in larger trials.
Effect of coenzyme Q10 on spinal cord ischemia-reperfusion injury
Authors: Hwang Jin-Young , Min Seong-Won , Jeon Young-Tae , Hwang Jung-Won , Park Sang-Heon , Kim Jin-Hee , Han Sung-Hee 
Published: January 2015

OBJECT
Spinal cord ischemia remains a serious complication of thoracoabdominal aortic aneurysm surgery. Coenzyme Q10, a potent antioxidant, has been reported to exert a neuroprotective effect. In the present study, we evaluated the effect of coenzyme Q10 pretreatment on spinal cord ischemia-reperfusion injury.

METHODS
Male Sprague-Dawley rats were treated with either 300 mg/kg coenzyme Q10 (CoQ10 group, n = 12) or saline (control and sham groups, n = 12 for each group) for 5 days before ischemia. Spinal cord ischemia was induced in the control and CoQ10 groups. Neurological function was assessed using the Basso-Beattie-Bresnahan (BBB) motor rating scale until 7 days after reperfusion, and then the spinal cord was harvested for histopathological examinations and an evaluation of malondialdehyde level.

RESULTS
On post-reperfusion Day 1, the CoQ10 group showed higher BBB scores compared with those in the control group, although the difference was not significant. However, on Day 2, the CoQ10 group showed a significantly higher BBB score than the control group (14.0 [10.3–15.0] vs 8.0 [5.0–9.8], median [IQR], respectively; p = 0.021), and this trend was maintained until Day 7 (17.5 [16.0–18.0] vs 9.0 [6.5–12.8], respectively; p < 0.001). Compared with the control group, the CoQ10 group had more normal motor neurons (p = 0.003), fewer apoptotic changes (p = 0.003) and a lower level of tissue malondialdehyde (p = 0.024).

CONCLUSIONS
Pretreatment with 300 mg/kg coenzyme Q10 resulted in significantly improved neurological function and preservation of more normal motor neurons.
Arterial spin labeling magnetic resonance imaging: toward noninvasive diagnosis and follow-up of pediatric brain arteriovenous malformations
Authors: Blauwblomme Thomas , Naggara Olivier , Brunelle Francis , Grévent David , Puget Stéphanie , Di Rocco Federico , Beccaria Kevin , Paternoster Giovanna , Bourgeois Marie , Kossorotoff Manoelle , Zerah Michel , Sainte-Rose Christian , Boddaert Nathalie 
Published: January 2015

OBJECT
Arterial spin labeling (ASL)-MRI is becoming a routinely used sequence for ischemic strokes, as it quantifies cerebral blood flow (CBF) without the need for contrast injection. As brain arteriovenous malformations (AVMs) are highflow vascular abnormalities, increased CBF can be identified inside the nidus or draining veins. The authors aimed to analyze the relevance of ASL-MRI in the diagnosis and follow-up of children with brain AVM.

METHODS
The authors performed a retrospective analysis of 21 patients who had undergone digital subtraction angiography (DSA) and pseudo-continuous ASL-MRI for the diagnosis or follow-up of brain AVM after radiosurgery or embolization. They compared the AVM nidus location between ASL-MRI and 3D contrast-enhanced T1 MRI, as well as the CBF values obtained in the nidus (CBFnidus) and the normal cortex (CBFcortex) before and after treatment.

RESULTS
The ASL-MRI correctly demonstrated the nidus location in all cases. Nidal perfusion (mean CBFnidus 137.7 ml/100 mg/min) was significantly higher than perfusion in the contralateral normal cortex (mean CBFcortex 58.6 ml/100 mg/min; p < 0.0001, Mann-Whitney test). Among 3 patients followed up after embolization, a reduction in both AVM size and CBF values was noted. Among 5 patients followed up after radiosurgery, a reduction in the nidus size was observed, whereas CBFnidus remained higher than CBFcortex.

CONCLUSIONS
In this study, ASL-MRI revealed nidus location and patency after treatment thanks to its ability to demonstrate focal increased CBF values. Absolute quantification of CBF values could be relevant in the follow-up of pediatric brain AVM after partial treatment, although this must be confirmed in larger prospective trials.
Comparison of two minimally invasive surgery strategies to treat adult spinal deformity
Authors: Park Paul , Wang Michael Y. , Lafage Virginie , Nguyen Stacie , Ziewacz John , Okonkwo David O. , Uribe Juan S. , Eastlack Robert K. , Anand Neel , Haque Raqeeb , Fessler Richard G. , Kanter Adam S. , Deviren Vedat , La Marca Frank , Smith Justin S. , Shaffrey Christopher I. , Mundis Gregory M. , Mummaneni Praveen V. 
Published: January 2015

OBJECT
Minimally invasive surgery (MIS) techniques are becoming a more common means of treating adult spinal deformity (ASD). The aim of this study was to compare the hybrid (HYB) surgical approach, involving minimally invasive lateral interbody fusion with open posterior instrumented fusion, to the circumferential MIS (cMIS) approach to treat ASD.

METHODS
The authors performed a retrospective, multicenter study utilizing data collected in 105 patients with ASD who were treated via MIS techniques. Criteria for inclusion were age older than 45 years, coronal Cobb angle greater than 20°, and a minimum of 1 year of follow-up. Patients were stratified into 2 groups: HYB (n = 62) and cMIS (n = 43).

RESULTS
The mean age was 60.7 years in the HYB group and 61.0 years in the cMIS group (p = 0.910). A mean of 3.6 interbody fusions were performed in the HYB group compared with a mean of 4.0 interbody fusions in the cMIS group (p = 0.086). Posterior fusion involved a mean of 6.9 levels in the HYB group and a mean of 5.1 levels in the cMIS group (p = 0.003). The mean follow-up was 31.3 months for the HYB group and 38.3 months for the cMIS group. The mean Oswestry Disability Index (ODI) score improved by 30.6 and 25.7, and the mean visual analog scale (VAS) scores for back/leg pain improved by 2.4/2.5 and 3.8/4.2 for the HYB and cMIS groups, respectively. There was no significant difference between groups with regard to ODI or VAS scores. For the HYB group, the lumbar coronal Cobb angle decreased by 13.5°, lumbar lordosis (LL) increased by 8.2°, sagittal vertical axis (SVA) decreased by 2.2 mm, and LL–pelvic incidence (LL-PI) mismatch decreased by 8.6°. For the cMIS group, the lumbar coronal Cobb angle decreased by 10.3°, LL improved by 3.0°, SVA increased by 2.1 mm, and LL-PI decreased by 2.2°. There were no significant differences in these radiographic parameters between groups. The complication rate, however, was higher in the HYB group (55%) than in the cMIS group (33%) (p = 0.024).

CONCLUSIONS
Both HYB and cMIS approaches resulted in clinical improvement, as evidenced by decreased ODI and VAS pain scores. While there was no significant difference in degree of radiographic correction between groups, the HYB group had greater absolute improvement in degree of lumbar coronal Cobb angle correction, increased LL, decreased SVA, and decreased LL-PI. The complication rate, however, was higher with the HYB approach than with the cMIS approach.
Thème II. Processus de précipitation et mesures (Process of precipitation and measures)
Authors: Muxart Tatiana 
Published: January 2015

Abstract. - Precipitation process of CaCO3 in continental medium area are reviewed. Different examples from semi-arid, mediterranean and temperate climates show the action of micro-organisms and lower vegetables in the waterfall deposits and fluviatile carbonaceous concretions.
The tufa deposits' age may be determined by estimating the annual growth rate of continental biohermes from stromatolithic rhythm or by 14C absolute datation. This last method has been applied to the U.K. tufa.
The effect of intramedullary pin size and monocortical screw configuration on locking compression plate-rod constructs in an in vitro fracture gap model
Authors: Glyde M. , Hosgood G. , Day R. , Pearson T. 
Published: January 2015

SummaryObjective: To investigate the effect of intramedullary pin size in combination with various monocortical screw configurations on locking compression plate-rod constructs.Methods: A synthetic bone model with a 40 mm fracture gap was used. Locking compression plates with monocortical locking screws were tested with no pin (LCP-Mono) and intramedullary pins of 20% (LCPR-20), 30% (LCPR-30) and 40% (LCPR-40) of intramedullary diameter. Locking compression plates with bicortical screws (LCP-Bi) were also tested. Screw configurations with two or three screws per fragment modelled long (8-hole), intermediate (6-hole), and short (4-hole) plate working lengths. Responses to axial compression, biplanar four-point bending and axial load-to-failure were recorded.Results: LCP-Bi were not significantly different from LCP-Mono control for any of the outcome variables. In bending, LCPR-20 were not significantly different from LCP-Bi and LCP-Mono. The LCPR-30 were stiffer than LCPR-20 and the controls. The LCPR-40 constructs were stiffer than all other constructs. The addition of an intramedullary pin of any size provided a significant increase in axial stiffness and load to failure. This effect was incremental with increasing intramedullary pin diameter. As plate working length decreased there was a significant increase in stiffness across all constructs.Clinical significance: A pin of any size increases resistance to axial loads whereas a pin of at least 30% intramedullary diameter is required to increase bending stiffness. Short plate working lengths provide maximum stiffness. However, the overwhelming effect of intramedullary pin size obviates the effect of changing working length on construct stiffness.
Isolation and characterization of 22 EST‐SSR markers for the genus Thujopsis (Cupressaceae)
Authors: Sato Miyako , Hasegawa Yoichi , Mishima Kentaro , Takata Katsuhiko 
Published: January 2015

• Premise of the study: Expressed sequence tag–simple sequence repeat (EST‐SSR) markers were developed from Thujopsis dolabrata var. hondae (Cupressaceae) using Illumina sequencing to investigate the genetic diversity and population structure of the genus Thujopsis.• Methods and Results: Twenty‐two primer pairs were developed from ESTs of T. dolabrata var. hondae. The primers amplified di‐ and trinucleotide repeat‐containing sequences. Polymorphisms were assessed in 81 individuals from two T. dolabrata var. hondae populations and one T. dolabrata population. The number of alleles ranged from one to 17 per locus. The observed and expected heterozygosities ranged from 0.000 to 1.000 and from 0.000 to 0.926, respectively.• Conclusions: These new EST‐SSR markers will be useful in analyses of the genetic diversity and population structure of the genus Thujopsis.
Microsatellite marker development for the coastal dune shrub Prunus maritima (Rosaceae)
Authors: Badgley Emily M. , Grubisha Lisa C. , Roland Anna K. , Connolly Bryan A. , Klooster Matthew R. 
Published: January 2015

• Premise of the study: Microsatellite primers were developed in the beach plum, Prunus maritima, to investigate the genetic composition of remaining populations in need of conservation and, in future studies, to determine its relation to P. maritima var. gravesii.• Methods and Results: Fourteen primer pairs were identified and tested in four populations throughout the species’ geographic range. Of these 14 loci, 12 were shown to be polymorphic among a total of 60 P. maritima individuals sampled (15 individuals sampled from four populations). Among the polymorphic loci, the number of alleles ranged from two to 10 and observed heterozygosity of loci ranged from 0.07 to 0.93 among specimens tested.• Conclusions: These microsatellites will be useful in evaluating the population genetic composition of P. maritima and in developing approaches for further conservation and management of this species within the endangered coastal dune ecosystem of the northeastern United States.
La formation universitaire des infirmières au Brésil : trois expériences
Authors: Fortuna Cinira Magali , Ribeiro Santana Fabiana , Spagnol Carla Aparecida 
Published: January 2015

La façon de former les professionnels en soins infirmiers est liée à l’histoire et au contexte socio-politique et économique. L’article discute la formation universitaire d’infirmier(ère) au Brésil dans trois universités publiques différentes : à l’Université de São Paulo, site de Ribeirão Preto, à l’Université Fédérale de Goiás, site de Catalão et à l’Université Fédérale du Minas Gerais, site de Belo Horizonte. Il explicite leurs défis, leurs différences et similitudes. Les réseaux de services de santé, les universités et la formation universitaire des infirmières sont très diversifiés sur le territoire brésilien. Une loi nationale règle la formation des infirmières, mais les universités ont une certaine autonomie pour appliquer ces programmes. Comment s’est structurée la formation des infirmières dans les trois universités qui sont comparées ? Même avec des ressources et des histoires différentes, les programmes de formation ont pour objectifs la prise en charge des soins intégraux et la qualité de tous les services sanitaires et sociaux du pays. La réalisation de ce projet est conditionnée, dans chacune des universités, par la réalité et la situation des réseaux de santé et des universités, ainsi que par le travail des professeurs et des infirmières.
Déplacement social et entrées en agriculture
Authors: Paranthoën Jean-Baptiste 
Published: January 2015

Résumé À partir du cas de l’installation de deux maraîchers issus de la « petite bourgeoisie parisienne », l’article se propose d’étudier les aménagements successifs et les modalités d’ajustement dans l’analyse de la mobilité sociale. À priori improbables, ces modes d’entrée « atypiques » en agriculture sont rendus possibles par la convergence de l’enseignement général et de l’enseignement agricole et leur valorisation par les membres contestataires de la profession agricole et des consommateurs attachés à la qualité des produits. La comparaison des deux carrières de déplacement fait apparaître l’importance de la contextualisation et de la périodisation des ressources mobilisées pour comprendre comment l’entrée en agriculture peut paradoxalement participer à prolonger l’indétermination des devenirs sociaux.
Des « paysans » chez les cheminots
Authors: Mischi Julian 
Published: January 2015

Résumé À partir d'une enquête de terrain menée dans une région rurale française, cet article analyse la situation de cheminots issus de familles agricoles. À l'encontre de la confusion entre départ de la profession agricole et exode rural, il envisage une sortie de l'agriculture qui ne s'accompagne pas (ou peu) d'une mobilité géographique et éclaire l'interdépendance entre agriculteurs et ouvriers dans le même territoire. Analyser des trajectoires de cheminots issus du monde paysan dévoile l'aspect composite des socialisations populaires en milieu rural, marquées par des tensions entre héritages familiaux agricoles et sociabilités professionnelles industrielles. Après une mise en perspective socio-historique des processus de mobilités de l'agriculture vers l'industrie, nous analysons en quoi la proximité avec l'univers agricole alimente des jeux de réputation et des stratégies distinctives au sein d'un atelier SNCF et de son syndicat CGT. Une étude de cas vise ensuite à cerner les processus de socialisation ouvrière et militante d'un « cheminot paysan » devenu syndicaliste.
FI-STAR Online Personalised Cardiac Rehabilitation Solution
Authors: Busnatu Stefan Sebastian , Sinescu Crina Julieta 
Published: January 2015

Background:
Advanced disease prevention solutions using telemedicine are vital for the future in order to decrease the burden produced by the cardio-vascular diseases. This solutions need to ensure more accessibility, high performance and good data privacy.
Material and Method:
Study groups consist of 48 acute myocardial infarction patients: 24 home monitored using telemedicine and 24 control group performing unmonitored rehabilitation. The process will have two phases: the inpatient period will be common (5-7 days) and the outpatient period (7 weeks). The monitored group will receive a set of Bluetooth capable monitoring devices at discharge, a blood pressure device, a cardio watch, a pulsoxymeter, an ECG chest strap and a Smartphone with the application installed. The application that will be built from scratch will contain the nutritional, medical and physical activity plan and also has monitoring and treatment adjustment functions by the medical personnel
Results: Before hospital discharge and at the end of the program all patients will perform an ECG treadmill test, which summed with other medical investigations, will quantify the cardiac fitness level and their improvement. Also using a MAST personalized model there will be assessed a set of performance indicators.
Conclusions: The Online Cardiac rehabilitation solution will be a light and secure software, built using Specific Enablers, technology created as generic enablers in the FI-WARE project. This is hoped to offer more patient independence, improve their cardiac fitness and quality of life and reduces the high cost that cardiovascular disease brings to the medical system.
Refining a socio-economic status scale for use in community-based health research in India
Authors: Dudeja P , Bahuguna P , Singh A , Bhatnagar N 
Published: January 2015

Objective:
Socio economic status is an important determinant of health and disease in population. Various scales for measuring the same exist in modern Indian society each with it's own limitations. Present study was done to abridge the existing and latest available Aggarwal Scale. Study Design: Cross Sectional Study

Material and methods:
All relevant information pertaining to Aggarwal et al scale was collected for 197 households and analyzed in SPSS 16. Data reduction was done using Factor Analysis (FA) under which Principal Components Analysis (PCA) was used.

Results:
Four components were selected based on criteria Eigen value of more than one and elbowing in scree plot. All the 22 items of Aggarwal et al were divided among these 4 components. Based on factor loadings four reduced scales were constructed. Percentage agreement of reduced scales with original scale increased as we increased the number of items in the scale. Analysis narrowed down the 22 items of Aggarwal et al scale to six items e.g. locality, education of husband/ wife, occupation of husband/ wife, family possessions, caste and monthly per capita income. These 6 items together accounted for 49% of the variation and can be taken as a surrogate measure of SES of the family.

Conclusion:
We have presented reduced versions of Aggarwal et al scale along with degree of agreement with the original scale. Authors propose the use of these scales to measure SES to overcome the time constraint in practicing research.
An audit of histopathology reports of carcinoma endometrium
Authors: Deodhar KK , Rekhi B , Menon S , Ganesh B 
Published: January 2015

Background:
The aim was to see, compliance to minimum data information in carcinoma endometrium reports, in a team of 13 pathologists, and also to analyze these parameters e.g. tumor size, type, grade, depth of myometrial invasion, lymph node yield, pTNM stage etc.

Materials and Methods:
During the period of 2008-2010, from the files of Pathology department of our hospital, reports of 114 cases of carcinoma endometrium, who were operated in house, were analyzed.

Results:
The median age was 58.04 years and median tumor size was 4 cm. Endometrioid adenocarcinoma was the most common type (82.5%), followed by malignant mixed Mullerian tumor (MMMT) (6.1%) and Serous carcinoma (3.5%). Grade 2 was the commonest tumor grade (42.1%). Less than half of myometrial invasion was seen in 50% of the cases and more than half of the myometrial invasion was seen in 46.5% of cases. (Information was not available in four cases). Parametrial involvement was seen in 5.3% cases. The pTNM stage was not mentioned in 71.9% reports. The median lymph node yield was 15.

Conclusion:
The compliance to adhere to and to provide minimum data information in carcinoma endometrium reports is generally good. Lymph node yield is reasonable. Mentioning of pTNM staging is to be done more meticulously. Use of proformas/checklists is recommended.