bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Crowdless Future? Generative AI and Creative Problem-Solving
Authors: Boussioux Léonard , Lane Jacqueline N. , Zhang Miaomiao , Jacimovic Vladimir , Lakhani Karim R. 
Published: August 2024

The rapid advances in generative artificial intelligence (AI) open up attractive opportunities for creative problem-solving through human-guided AI partnerships. To explore this potential, we initiated a crowdsourcing challenge focused on sustainable, circular economy business ideas generated by the human crowd (HC) and collaborative human-AI efforts using two alternative forms of solution search. The challenge attracted 125 global solvers from various industries, and we used strategic prompt engineering to generate the human-AI solutions. We recruited 300 external human evaluators to judge a randomized selection of 13 out of 234 solutions, totaling 3,900 evaluator-solution pairs. Our results indicate that while human crowd solutions exhibited higher novelty—both on average and for highly novel outcomes—human-AI solutions demonstrated superior strategic viability, financial and environmental value, and overall quality. Notably, human-AI solutions cocreated through differentiated search, where human-guided prompts instructed the large language model to sequentially generate outputs distinct from previous iterations, outperformed solutions generated through independent search. By incorporating “AI in the loop” into human-centered creative problem-solving, our study demonstrates a scalable, cost-effective approach to augment the early innovation phases and lays the groundwork for investigating how integrating human-AI solution search processes can drive more impactful innovations. Funding: This work was supported by Harvard Business School (Division of Research and Faculty Development) and the Laboratory for Innovation Science at Harvard (LISH) at the Digital Data and Design (D3) Institute at Harvard. Supplemental Material: The online appendix is available at https://doi.org/10.1287/orsc.2023.18430 .
Effects of traditional Chinese medicine on symptoms of patients with spleen and stomach deficiency-related tinnitus
Authors: Cui Na , Zhao Chen , Xue Jun-Lai , Zhu Xue-Wei 
Published: August 2024

BACKGROUND
Tinnitus affects 10%-30% of the population. Recent evidence suggests that tinnitus is associated with spleen deficiency. However, compared with kidney deficiency-related tinnitus, less research has been conducted on the impact of spleen deficiency-related tinnitus.
AIM
To investigate the clinical efficacy of using Guipi Wan and dietary and lifestyle modification based on traditional Chinese medicine for treatment of patients with spleen and stomach deficiency-related tinnitus.
METHODS
We enrolled 110 patients with spleen and stomach deficiency-related tinnitus who were distributed into treatment (58 cases) and control (52 cases) groups. Tinnitus severity, sleep quality and emotional state were assessed by questionnaires [Tinnitus Evaluation Questionnaire (TEQ); Pittsburgh Sleep Quality Index (PSQI); Depression-Anxiety-Stress Scale-21 (DASS-21)] that were used for analysis in the two groups during the initial and intervention and after. In the treatment group, patients were treated with oral administration of Guipi Wan and consulted for healthy dietary and lifestyle modification. In the control group, patients were only assessed and not treated.
RESULTS
At the end of the 6-months, TEQ scores decreased significantly in the treatment group (P = 0.021) but not in the Control group. Significant effects in the treatment group were noted for PSQI total score (P = 0.043) and several PSQI component scores in the treatment group (P < 0.05). After treatment, the DASS-21 scores were significantly reduced in the treatment group (P < 0.05).
CONCLUSION
Guipi Wan combined with dietary and lifestyle modification based on regulating the spleen and stomach can be considered core to the treatment of tinnitus related to spleen and stomach deficiency.
Self-expanding metal stent for relieving the stricture after endoscopic injection for esophageal varices
Authors: Zhang Fu-Long , Xu Jing , Jiang Yu-Hong , Zhu Yuan-Dong , Shi Yan , Li Xiao , Wang Hai , Huang Chao-Jun , Zhou Chun-Hua , Zhu Qun , Chen Jing-Wen 
Published: August 2024

BACKGROUND
Esophageal stricture is one of the complications after esophageal varices sclerotherapy injection (ESI), and the incidence rate is between 2%-10%.
AIM
To explore the efficacy of self-expanding metal stent (SEMS) for the stricture after endoscopic injection with cyanoacrylate (CYA) and sclerotherapy for esophageal varices.
METHODS
We retrospectively analyzed the efficacy of SEMS to improve the stricture after endoscopic injection with CYA and sclerotherapy for esophageal varices in 4 patients from February 2023 to June 2023.
RESULTS
The strictures were improved in four patients after stenting. The stent was removed after two weeks because of chest pain with embedding into esophageal mucosa in one patient. The stent was removed after one month, however, the stent was reinserted because of the strictures happening again in two patients. The stent was removed after three months, however, the stent was reinserted because of the strictures happening again in one patient. The stent embedded into esophageal mucosa in three patients. There were 3 patients suffered reflux esophagitis, and the acid reflux was relieved by taking hydrotalcite. There was no other complication of esophageal perforation, bleeding from varices or infection.
CONCLUSION
SEMS may relieve the stricture which happened after endoscopic injection with CYA and sclerotherapy for esophageal varices. However, when we should remove the stent still needs to be explored.
Incidental renal cell carcinoma post bilateral nephrectomy in autosomal dominant polycystic kidney disease
Authors: Shin Min-Ho , Choi Nam-Kyu 
Published: August 2024

BACKGROUND
Renal cell carcinoma (RCC) is more common in patients with autosomal dominant polycystic kidney disease (ADPKD) than in the general population. Diagnosing RCC in ADPKD is challenging due to the presence of multiple renal cysts, often leading to delays and difficulties in distinguishing RCC from cyst infection or hemorrhage.
AIM
To analyze the prevalence and characterize the clinical features of RCC in patients with ADPKD undergoing simultaneous bilateral native nephrectomy.
METHODS
Between May 2017 and April 2024, 19 ADPKD patients undergoing hemodialysis and awaiting kidney transplantation due to end-stage renal disease (ESRD) underwent bilateral nephrectomies in a single center. Parameters such as patient characteristics, intraoperative blood loss, blood transfusion volume, length of hospital stay, and postoperative complications were documented. Pathological findings for RCC were reviewed.
RESULTS
A total of 38 kidneys were excised from 19 patients, with a mean age of 56.8 years and an average hemodialysis duration of 84.2 months. Eight patients underwent open nephrectomies, and 11 underwent hand-assisted laparoscopic nephrectomies. RCC was detected in 15.8% of kidneys, affecting 21.1% of patients. Two patients had multifocal RCC in both kidneys. All RCC cases were pT1 stage, with the largest lesion averaging 16.5 mm in diameter. The average operative duration was 120 minutes, with intraoperative blood loss averaging 184.2 mL. Five patients required blood transfusions. Postoperative complications occurred in five patients, with a mean hospital stay of 17.1 days. The mean follow-up period was 28.1 months.
CONCLUSION
The prevalence of RCC is higher in patients with ADPKD with ESRD than in those with ESRD alone. Thus, clinicians should be cautious and implement surveillance programs to monitor the development of RCC in patients with ADPKD, particularly those on dialysis.
Effect of intraoperative injection of esketamine on postoperative analgesia and postoperative rehabilitation after cesarean section
Authors: Chen Hong-Zhuan , Gao Yi , Li Ke-Ke , An Li , Yan Jing , Li Hong , Zhang Jin 
Published: August 2024

BACKGROUND
Following cesarean section, a significant number of women encounter moderate to severe pain. Inadequate management of acute pain post-cesarean section can have far-reaching implications, adversely impacting maternal emotional well-being, daily activities, breastfeeding, and neonatal care. It may also impede maternal organ function recovery, leading to escalated opioid usage, heightened risk of postpartum depression, and the development of chronic postoperative pain. Both the Chinese Enhanced Recovery After Surgery (ERAS) guidelines and the American ERAS Society guidelines consistently advocate for the adoption of multimodal analgesia protocols in post-cesarean section pain management. Esketamine, functioning as an antagonist of the N-Methyl-D-Aspartate receptor, has been validated for pain management in surgical patients and has exhibited effectiveness in depression treatment. Research has suggested that incorporating esketamine into postoperative pain management via pain pumps can lead to improvements in short-term depression and pain outcomes. This study aims to assess the efficacy and safety of administering a single dose of esketamine during cesarean section.
AIM
To investigate the effect of intraoperative injection of esketamine on postoperative analgesia and postoperative rehabilitation after cesarean section.
METHODS
A total of 315 women undergoing elective cesarean section under combined spinal-epidural anesthesia were randomized into three groups: low-dose esketamine (0.15 mg/kg), high-dose esketamine (0.25 mg/kg), and control (saline). Postoperative Visual Analog Scale (VAS) scores were recorded at 6 hours, 12 hours, 24 hours, and 48 hours. Edinburgh Postnatal Depression Scale (EPDS) scores were noted on 2 days, 7 days and 42 days. Ramsay sedation scores were assessed at specified intervals post-injection. Postoperative adverse reactions were also recorded.
RESULTS
Low-dose group and high-dose group compared to control group, had significantly lower postoperative VAS pain scores at 6 hours 12 hours, and 24 hours (P < 0.05), with reduced analgesic usage (P < 0.05). EPDS scores and postpartum depression rates were significantly lower on 2 days and 7 days (P < 0.05). No significant differences in first exhaust and defecation times were observed (P > 0.05), but ambulation times were shorter (P < 0.05). Ramsay scores were higher at 5 minutes, 15 minutes, and upon room exit (P < 0.05). Low-dose group and high-dose group had higher incidences of hallucination, lethargy, and diplopia within 2 hours (P < 0.05), and with low-dose group had lower incidences of hallucination, lethargy, and diplopia than high-dose group (P < 0.05).
CONCLUSION
Esketamine enhances analgesia and postpartum recovery; a 0.15 mg/kg dose is optimal for cesarean sections, balancing efficacy with minimized adverse effects.
Virtual reality for preoperative patient education: Impact on satisfaction, usability, and burnout from the perspective of new nurses
Authors: Kim Jiyoung , Kim Donghyun , Oh Sang-Ha , Kwon Hyeokjae 
Published: August 2024

BACKGROUND
Traditional paper-based preoperative patient education is a struggle for new nurses and requires extensive training. In this situation, virtual reality technology can help the new nurses. Despite its potential benefits, there are studies on patient satisfaction but there is limited information on the usability of virtual reality (VR) technology for new nurses in giving preoperative education to patients.
AIM
To investigate the impact on satisfaction, usability, and burnout of a system using VR technology in preoperative patient education.
METHODS
The study involved 20 nurses from the plastic surgery ward and 80 patients admitted between April and May 2019. Each nurse taught four patients: Two using traditional verbal education and two using virtual reality. The System Usability Scale, After-Scenario Questionnaire, and Maslach Burnout Inventory (MBI) were employed to evaluate the impact of these education methods.
RESULTS
The VR education groups showed a statistically higher satisfaction than the traditional verbal education groups. Among the three subscales of the MBI, emotional exhaustion and personal accomplishment improved statistically significantly. VR was also better in terms of usability.
CONCLUSION
This study suggests VR enhances usability and reduces burnout in nurses, but further research is needed to assess its impact on depersonalization and objective measures like stress and heart rate.
Roman Pollak w świetle korespondencji z Bogdanem Zakrzewskim
Authors: Lijewska Elżbieta 
Published: August 2024

The article presents an image of professor Roman Pollak based on a collection of letters from Bogdan Zakrzewski (from the Archive of the Polish Academy of Sciences in Poznan), Pollak’s letters to the former student of his (since 2013, held in the Special Archive of the Ossoliński National Institute) and the reminiscences of Barbara Zakrzewska (in particular, the ones not published before the fall of communism in Poland). The analysis of the subject material presents a portrait of the professor as a renowned teacher, a demanding and kind lecturer, an open-minded scientist passionate especially about the Polish-Italian relationships and a skilled organiser of academic life who remained independent under the communist regime. The article emphasises the importance of the correspondence between the two professors for understanding the history of early postwar and subsequent Polish studies in Poznan and Wrocław, the history of “Pamiętnik Literacki” (Literary Memoir) and other research of both scholars. It also underscores the value of the analysed letters for determining the fate of those who graduated from Polish studies in Poznań thanks to the fact that professor Pollak maintained contacts with them after their graduation and supported them later in life.
The feet of orthogonal Buekenhout–Metz unitals
Authors: Barwick S.G. , Jackson W.-A. , Wild P. 
Published: August 2024

Abstract
In this article we look at the geometric structure of the feet of an orthogonal Buekenhout–Metz unital 𝓤 in PG(2, q
2). We show that the feet of each point form a set of type (0, 1, 2, 4). Further, we discuss the structure of any 4-secants, and determine exactly when the feet form an arc.
Some aspects of normal curve on smooth surface under isometry
Authors: Singh Kuljeet , Sharma Sandeep , Bhardwaj Arun Kumar 
Published: August 2024

Abstract
The normal curve is a space curve that plays an important role in the field of differential geometry. This research focuses on analyzing the properties of normal curves on smooth immersed surfaces, considering their invariance under isometric transformations. The primary contribution of this article is to explore the requirements for the image of a normal curve that preserves its invariance under isometric transformations. In this article, we investigate the invariant condition for the component of the position vector of the normal curves under isometry and compute the expression for the normal and geodesic curvature of such curves. Moreover, it has been investigated that the geodesic curvature and Christoffel symbols remain unchanged under the isometry of surfaces in

R

3

{{\mathbb{R}}}^{3}

.
Derivation of Hermite-Hadamard-Jensen-Mercer conticrete inequalities for Atangana-Baleanu fractional integrals by means of majorization
Authors: Wu Shanhe , Khan Muhammad Adil , Faisal Shah , Saeed Tareq , Nwaeze Eze R. 
Published: August 2024

Abstract
This article is mainly concerned to link the Hermite-Hadamard and the Jensen-Mercer inequalities by using majorization theory and fractional calculus. We derive the Hermite-Hadamard-Jensen-Mercer-type inequalities in conticrete form, which serve as both discrete and continuous inequalities at the same time, for majorized tuples in the framework of the famous Atangana-Baleanu fractional operators. Also, the main inequalities encompass the previously established inequalities as special cases. Using generalized Mercer’s inequality, we also investigate the weighted forms of our major inequalities for certain monotonic tuples. Furthermore, the derivation of new integral identities enables us to construct bounds for the discrepancy of the terms concerning the main results. These bounds are constructed by incorporating the convexity of

∣
f
′
∣

| f^{\prime} |

and

∣
f
′
∣

q

(

q
>
1

)

{| f^{\prime} | }^{q}\hspace{0.33em}\left(q\gt 1)

and making use of power mean and Hölder inequalities along with the established identities.
Decreasing and complete monotonicity of functions defined by derivatives of completely monotonic function involving trigamma function
Authors: Yin Hong-Ping , Han Ling-Xiong , Qi Feng 
Published: August 2024

Abstract
In this study, using convolution theorem of the Laplace transforms, a monotonicity rule for the ratio of two Laplace transforms, Bernstein’s theorem for completely monotonic functions, and other analytic techniques, the authors verify decreasing property of a ratio between three derivatives of a function involving trigamma function and find the necessary and sufficient conditions for a function defined by three derivatives of a function involving trigamma function to be completely monotonic. These results confirm previous guesses posed by Qi and generalize the corresponding known conclusions.
Unveiling Connections between Stress, Anxiety, Depression, and Delinquency Proneness: Analysing the General Strain Theory
Authors: Punia Poonam , Jangra Swati , Phor Manju 
Published: August 2024

Abstract

Background/objective
The present study explored the correlation between different types of stress (acute and chronic) and the influence of their negative emotional manifestations on delinquent tendencies in adolescent students. Within the framework of the general strain theory, the study aims to analyse the intermediary role of depression in the relationship between anxiety and stress. This study investigated the relationship between stress, anxiety, depression, and delinquency proneness in adolescent school students in Sonepat, India.

Methods and materials
The present study utilised the descriptive survey method. Data were collected using standardised questionnaires based on self-reporting. Anxiety depression and stress scale and delinquency proneness scale were used to collect data from a sample of 200 students aged between 14 and 18 years from various schools in the district.

Results
The comparison (using independent t-test) revealed that levels of anxiety (t = −1.683, p = 0.094), depression (t = −0.196, p = 0.845), and delinquency proneness (t = −1.348, p = 0.179) were not significantly different between males and females, with the exception of stress (t = −2.929, p = 0.004). Furthermore, results of the Pearson product-moment correlation indicated a significant positive association between stress, anxiety, depression, and delinquency proneness. Regression analysis results showed that stress, anxiety, and depression have a significant effect on delinquency proneness (F(3, 196) = 28.2, p < 0.001). It further indicated that stress, anxiety, and depression cause 29.1% variation in delinquency proneness. In addition, results of mediation analysis showed that depression mediates the relationship between anxiety and delinquency proneness (accounts for 82.1% mediation). Furthermore, depression also mediates the relationship between stress and delinquency proneness (accounts for 74.5% mediation).

Conclusions
The results support the general strain theory, which posits that strain (anxiety and stress) can lead to delinquency proneness, which is mediated by depression. Research shows that delinquency proneness, depression, and stress are prevalent among adolescents. To prevent juvenile delinquency, effective intervention programs should focus on equipping young people with interpersonal skills and coping strategies.
An examination of responses to ageist jokes
Authors: Miczo Nathan 
Published: August 2024

Abstract
Ageist humor is an everyday way that negative social attitudes (i.e., ageism) are circulated. Advances in the study of disparagement humor (prejudiced norm theory, the justification-suppression model) were utilized to examine responses to ageist humor in two studies. Study 1, comparing ageist and sexist comments, found no differences in perceived funniness between statements and jokes, though jokes were seen as less offensive and more confrontation-worthy. Participants believed they would be more offended by the statements than others. To the extent they found statements funny, participants believed the messages conveyed less offense to self and others, and that the statements were not worthy of confrontation, but thought others would believe they were. Older individuals found statements less funny and believed others would have negative reactions. Study 2 found no differences in funniness ratings for jokes targeting older and younger age groups. Two responses to the joke-teller emerged: challenge (including direct and indirect responses) and support (laughing or verbally expressing joke funniness). Funniness and joke-teller identification positively predicted both challenge and support, while experiencing negative emotion predicted more challenge and less support. Once again, age was associated with less funniness, as well as less identification, support, and challenge, but more negative emotion.
Exploring anesthetic-induced gene expression changes and immune cell dynamics in atrial tissue post-coronary artery bypass graft surgery
Authors: Bao Mengmeng , Wu Anshi 
Published: August 2024

Abstract

Background
This study leverages the GSE4386 dataset, obtained from atrial tissue samples post-coronary artery bypass graft (CABG) surgery, to investigate the impact of anesthetic agents (sevoflurane and propofol) on gene expression and immune cell infiltration.

Methods
Hierarchical clustering and box plots were employed for dataset preprocessing, highlighting a significant outlier (sample GSM99282), subsequently removed to ensure data integrity. Differentially expressed genes (DEGs) were identified using volcano plots based on specific log-fold-change and P-value thresholds. Additional analyses included the Friends approach, Spearman’s correlation, and gene set enrichment analysis (GSEA), exploring functional annotations and pathways.

Results
Heatmaps and bubble plots depicted DEGs, revealing distinct expression patterns between the sevoflurane and propofol groups. Friends analysis identified top genes based on log fold changes, further correlated using Spearman’s method. Gene Ontology and Kyoto Encyclopedia of Genes and Genomes enrichment analyses illustrated functional annotations of DEGs, while GSEA highlighted enriched biological categories. Immune cell infiltration analysis showcased varied cellular presence post-CABG. ESTIMATE algorithm scores demonstrated differences in immune, stroma, and estimate scores. Microenvironment Cell Populations-counter (MCPcounter) revealed an increased abundance of cytotoxic lymphocytes in the sevoflurane group, confirmed by a single sample GSEA. CIBERSORT algorithm identified distinct immune cell compositions, highlighting differences in macrophage M0 prevalence between sevoflurane and propofol groups.

Conclusions
This comprehensive analysis provides insights into anesthetic-induced gene expression changes and immune cell dynamics in atrial tissue post-CABG surgery. The identified DEGs and immune cell compositions offer potential biomarkers and therapeutic targets for refining anesthetic strategies in cardiac surgeries.