bluuebunny/crossref_metadata_2025_split huggingface dataset:
1546 – Personality Traits And Postpartum Depression: Results From Basic Study In Sweden
Authors: Koulouris P. , Iliadis S.I. , Sundström-Poromaa I. , Ekselius L. , Skalkidou A. , Papadopoulos F. 
Published: July 2013

IntroductionPostpartum depression (PPD), with a prevalence of about 10-15% in developed countries, has a major impact on both mother and child. Personality traits, mainly neuroticism, have been associated with affective disorders and in particular postpartum depression.ObjectivesTo examine if neuroticism is associated with depressive symptoms in pregnancy and post-partum, controlling for possible confounding factors.MethodsSince September 2009, all pregnant women in Uppsala, Sweden have been asked to participate in BASIC study, which is a population based, prospective study on mental health during pregnancy and post-partum. Women filled in the Swedish Scales of Personality (SSP), as well as the Edinburg Postnatal Depression Scale (EPDS) in pregnancy week 32. EPDS was also administered 6 weeks and 6 months postpartum. A factor analysis of SSP traits was conducted in our material and the three factor structure comprising neuroticism, aggressiveness and sensation seeking was confirmed. The association between personality traits and depressive symptoms was examined using binary logistic regression. High levels of neuroticism, aggressiveness and sensation seeking were defined as the highest quartile of each factor.ResultsHigh levels of neuroticism were strongly associated with depressive symptoms during pregnancy as well as at 6 weeks and 6 months post-partum, while aggressiveness and sensation seeking were not. After controlling for confounding factors, such as previous history of depression, employment, education, partner support and breastfeeding, neuroticism remained a significant predictor for depressive symptoms, at all three time-points.ConclusionsNeuroticism is an independent strong predictor of depressive symptoms during pregnancy and the postpartum period.
1548 – Correlates Of Psychoform And Somatoform Dissociation In Eating Diosrders (ed)
Authors: Espirito-Santo H. , Gonçalves L. , Marques M. , Rocha P. , Cassimo S. 
Published: July 2013

Psychoform dissociation is related with various kinds of traumatic experiences and somatoform dissociation with physical abuse, probably because dissociation blocks negative affects. The association between types of dissociation and types of trauma in eating disorders it is not clear. Our objective is to examine what are the correlates of psychoform and somatoform dissociation in ED. We assessed 29 voluntary ED patients (anorexia = 16; bulimia = 13) from one psychiatric consultation with the Dissociative Experiences Scale (DES), the Somatoform Dissociation Questionnaire (SDQ-20), the Traumatic Events Checklist (TEC), and the General Symptom Index (GSI) from the Brief Symptom Inventory (BSI).In anorexia, DES scores significantly correlated with GSI, anxiety, phobia, psychoticism, obsessive-compulsive, depressive, and paranoid symptoms, and with none of the trauma types. In bulimia, DES significantly correlated with GSI, and all of the BSI symptomatology except obsessive-compulsive and hostility; with emotional trauma (occurred between the 0-6 years of age), and familial trauma.In anorexia, SDQ-20 significantly correlated with GSI, and all of the BSI symptomatology except somatization and paranoid symptoms. In bulimia, SDQ-20 significantly correlated with GSI, and all BSI dimensions; with trauma, physical abuse, emotional trauma (occurred between the 0-6 years of age), and with familial trauma.These findings highlight the importance of considering psychopathological symptoms in the treatment of psychoform and somatoform dissociation in ED. A special caution should be given to infancy trauma occurred in the family in the treatment of dissociation in bulimia.
1551 – Is There Delusional Anorexia Nervosa?
Authors: Konstantakopoulos G. , Varsou E. , Ploumpidis D. , Dikeos D. , Ioannidi N. , Papadimitriou G.N. , Oulis P. 
Published: July 2013

IntroductionLack of insight is a major obstacle in treating patients with anorexia nervosa (AN). In everyday practice, clinicians often describe as delusional AN patients who strongly deny their emaciation.ObjectivesDespite their diagnostic and clinical significance the level of delusionality of body image beliefs in eating disorders (EDs) has not yet been systematically investigated.AimsIn the present study we assessed for the first time the delusionality of body image beliefs in AN subtypes and BN. We hypothesized that body image beliefs would be delusional only in a subgroup of AN patients and that the patients with restrictive AN would demonstrate the higher levels of delusionality.MethodsWe used the Brown Assessment of Beliefs Scale (BABS) to assess the degree of delusionality of body image beliefs in seventy-two participants: 39 with AN and 33 with BN. We also investigated the relationship between body image delusionality and other clinical characteristics in AN.ResultsOnly patients with anorexia nervosa (28.8%) had delusional body image beliefs, whereas overvalued ideas appeared to be frequent in both AN and BN. Body image delusionality in AN was associated with restrictive eating pathology, early onset of the disorder and body dissatisfaction.ConclusionsResults suggest that a delusional variant of anorexia nervosa represents the one end of a continuum of insight among patients with eating disorders. Delusionality constitutes a clinical feature independent of weight loss or eating pathology and thus a distinct component of AN psychopathology, contributing to treatment resistance and illness chronicity.
1555 – Repetitive Behaviors In Tourette Syndrome
Authors: Brenha M.M. , Rio C. 
Published: July 2013

IntroductionIn Tourette Syndrome (TS), a neuropsychiatric disorder, tics are frequently associated with obsessivecompulsive symptoms that not always fulfill criteria for Obsessive- Compulsive Disorder (OCD). Phenomenological, genetic and epidemiologic studies suggest a strong association between TS and OCD, not only in patients but also in their relatives. Obsessive-compulsive symptoms can be found in 28-63% of TS patients. Motor portions of cortico-striato-thalamic-cortical circuits are implicated in tics and compulsions. Integrating these repetitive behaviors in Obsessive-Compulsive (OC) spectrum, a continuum between Compulsion and Impulsion, OCD tic-free is positioned at the compulsive end and tic-related OCD and ST are positioned between the two poles.ObjectivesThis communication has as main objective to characterize the repetitive behaviors in TS by presenting the differences and similarities with compulsions.AimsTo integrate TS in OC spectrum.MethodsArticles’ selection in PUBMED and SCIENCEDIRECT databases and literature’s review about the theme.ResultsAccording to clinical features and treatment response, tic-related OCD has an intermediate position between OCD ticfree and TS, sharing common aspects with both entities.ConclusionsTS may be differenciated from OCD subgroups, namely tic-related OCD, by its clinical features and therapeutic response. The presence of repetitive touching actions and ecophenomena seems to discriminate TS from OCD. The phenomenological characterization of repetitive behaviors in TS is extremely important, as tic and compulsion’s treatment is different.
1563 – The Examiner's Effect On The Measurement Of Dissociation And Other Psychopathological Symptoms In College Students
Authors: Matreno J. , Espírito Santo H. 
Published: July 2013

ObjectiveThe aim of this research was to verify if there is a difference in dissociation or other psychopathological symptoms between two groups of college students when questioned by two different examiners.MethodThe Dissociative Experiences Scale, the Brief Symptom Inventory and the Marlowe-Crowne Social Desirability Scale were administered to 185 college students in Coimbra. In one group the examiner was of the same age and academic status, while in the other group the examiner was older and a professor.ResultsThe younger examiner’s group scored higher in the Dissociative Experiences Scale and in the Brief Symptom Inventory. There were no differences in the Marlowe-Crowne Social Desirability Scale.ConclusionsThe examiner does have an influence in the evaluation of psychopathological symptoms amongst college students and this occurs not because of social desirability, but because of cultural and environmental proximity, age and empathy with the examiner.ImplicationsThe results derived from mental health studies with college students should be interpreted cautiously, and who is the examiner should be pointed out.
1566 – The Relationship Between The 5-httlpr Gene, Major And Minor Life Events And Childhood Trauma And Depression, Anxiety And Suicidal Symptoms: a Clinical Study Among Adolescents
Authors: Apter A. , Oshry N. , Weizman A. , Frisch A. 
Published: July 2013

Life events (LEs) contribute to the development of psychiatric disorders such as anxiety and depression. Nevertheless, the power of the stress-affective disorders correlation is relatively low, suggesting the existence of moderating and mediating factors (Liu et al., 2000).Caspi et al. (2003), showed a mediating effect for short allele in the 5-HTTLPR gene to be a vulnerability factor for developing affective reaction towards life events.The present study t aimed to examine the intensity of anxiety, depression and suicidal symptoms within a clinical population as a function of the genetic vulnerability and LEs variables, focusing on adolescents. The sample consisted of 146 adolescents, aged from 11 to 18 years, 54 with main diagnosis of depression, 38 with anxiety disorder and 54 healthy control group.A post-hoc analysis yielded that only for the anxiety group, but not for the depressive group, the correlation between early trauma and the suicidal ideation is dependent on genetic vulnerability. As such, only for those who suffer from anxiety disorder who also have two short alleles (ss), the existence of childhood trauma predicts more suicidality that accompany their affective disorder., while for those with two long alleles, or for those with depression, this linkage does not have significance.
1570 – Cleavage Of Neuregulin 1 And Bace1 Expression In Frontal Cortex Of Schizophrenia Patients
Authors: Barakat A. , Bellingham S. , Hill A. , Boon W.C. , Evin G. 
Published: July 2013

IntroductionNeuregulin1 (Nrg1) is a candidate gene linked to schizophrenia. Cleavage of Nrg1 full-length (Nrg1-FL) precursor protein by BACE1 mediates activation of erbB receptors and triggers a cascade of downstream signalling events that lead to activation of GABA, NMDA, and nicotinic receptors. Studies with BACE1 knock out mouse models have demonstrated impaired Nrg1-/ErbB signalling leads to SZ-like phenotypes that can be rescued by antipsychotics.ObjectivesWe analysed frontal cortex brain tissue of schizophrenia (SZ) and healthy control (HC) subjects for expression of BACE1, Nrg1-FL and Nrg1 cleaved fragment.AimTo explore the possible mis-cleavage of Nrg1 by BACE1 in SZ as this may disrupt some neuronal circuits in the brain and trigger schizophrenia.MethodsSamples from Brodmann area 6 region (40 SZ and 20 HC) were homogenized with TRIzol and proteins were analysed by western blotting. Also samples were analysed for RNA integrity and 18 SZ and 20 HC with high RIN were selected for qRT-PCR study.ResultsAbout 50% decrease in Nrg1 C-terminal fragment (CTF) was observed in the SZ group compared to the HC group (p < 0.001). A strong correlation between Nrg-FL and BACE1 was observed (r = 0.82, P < 0.001). Results of qRT-PCR showed a significant increase in the expression of BACE1-432 splice variant in SZ compared to HC (P = 0.005). A strong inverse correlation was found between BACE1 activity and 432/501 BACE1 splice variants expression.ConclusionOur results suggest that altered expression of BACE1 and decreased cleavage of Nrg1 are associated with SZ.
1577 – A Historical Study Of The Work Of Frances Tustin
Authors: Ferreira J.A. , Abrão J.L.F. 
Published: July 2013

Frances Tustin was a renowned child therapist that, with her original conceptions and therapeutic effectiveness, stemming mainly from the clinical work with autistic and psychotic children, expanded the existing theories on the primitive states of mind influencing therapists in their clinical and academic work and acquiring a broad spectrum of activity. This study aimed to trace the course of the theoretical work of Frances Tustin in the original language in which it was produced. To this end, it was used a historical approach, to investigate the origins of a thought and its various contextual determinants as the biography of the author, the historical period, clinical cases, among others. The research material was the complete writings of Frances Tustin. From a detailed review process the work was divided into three main periods:1)Early Writings;2)Elaborations and3)Revisions.Her theoretical corpus has not only assisted the attendance of atypical children, but also psychotic, borderline and neurotic adult patients. It enabled contact and exchange experiences with workers from various institutions elucidating the affective aspects involved in the functioning of patients and the dynamics of their relationships with caregivers. Her theoretical and technical contributions are widely known and respected in many countries. It remains modern among the significant neuroscience advances as a complementary contribution for a greater understanding on the psychodynamics of the most regressed states of mind.
1578 – Process Of Interaction With Patients And Nurses - Approach Towards Severe Motor And Intellectual Disability With Severe Behavior Disorder In Japan-
Authors: Sejima K. , Aita C. , Yuzuriha T. 
Published: July 2013

IntroductionHizen Psychiatric Center has the first ward for Severe Behavior Disorder in Japan which has the highest number of severe cases. We have many specialized ways to intervene over the years, Habilitation, TEACCH Pharmacotherapy and Behavior therapy. On the otherhand, most of patients have traits (such as difficulty in communicating, severe self and other harming, pica) are easy to make their carer feel rewardless, conflict.ObjectivesTo have adequate understanding and give specialized supports for carer, we focus on experiences of care-giving, and analyze the process about formation of care-giving, what kind of rewards they acquire.MethodsHalf-constructed Interview with 10 Nurses at the ward and Qualitative Analysis based on Grounded Theory Approach.Results5 Upper Categories are produced(Shock) (Disgust) (Conflict) (Change) (Acceptance)and those can be the steps. This process is not linear and each nurse has each pattern of achievement and time.ConclusionsWe found the steps of care-giving formation even there are difficulty of interaction. To achieve (Change) (Acceptance)individually, we can suggest the way to make them feel rewarding. Carer (including Staff and Parent) are important environments for patients. It needs to empower them not to be anti-factor of care-giving.
1584 – Complicated Self-realization Of Persons With Clinical Diagnosis “stress-related Adjustment Disorder”
Authors: Bokhan T. 
Published: July 2013

Investigation supposed study of complicated self-realization of persons with clinical diagnosis “neurotic disorders, stressrelated” and problem of adaptive behavior (F10, ICD-10). Investigation included 128 persons at the age from 20 to 52 years old among which there are males - 40, females - 88.Methods usedQuality of Life Index (R. S. Eliot), Depressiveness Questionnaire (A. Beck), Meaning of Life Orientations (D. A. Leontyev), Tomsk Rigidity Questionnaire (G. V. Zalevsky), Coping-Strategies Rating (E. Heim), Thought Constructiveness Questionnaire (S. Epstein); Non-Complete Sentences Method by J. Nuttin; Statements’ Content Analysis Method, Methods of statistical analysis.ResultsComplicated self-realization in respondents is manifested as: uncertain life values and principles, experiences of nonachievement of their aims and perception of themselves as losers, anxious thoughts about their future. Inability of planning and organizing their time, feeling of its constant lack; complicated self-control and their decision making; closeness in selfexpression; thought and behavior activity rigidity are typical for them. Their emotional state is characterized by tension of personal experiences, conflicts and crises for recent time that is accompanied by feelings of guilt, shame and anger. Indices of physical state testify to bad sleep, decreased physical activity. Professional self-realization of respondents has been represented by variants: uncertainty of professional self-identification, character of self-realization has been represented by reproductive type, associated with deficient values; presence of strives to professional self-development in absence of idea of their realization. Stress tension as a “blockade” of self-realization is conditioned by unity of image of world and image of life of respondents.
1593 – Cognitive Impairment In Depression In Women
Authors: Marinescu I.P. , Udriştoiu T. , Marinescu D. , Pîrlog M.C. 
Published: July 2013

IntroductionDepression in women is supported by specific psychoendocrine factors. Neuroprotection is reduced in conditions of exposure to psychostress by increase of endogenous cortisol due to excessive HPA activity associated with somatic risks. Decrease of neuroprotection after hypercortisolemia due to excessive HPA activity is associated with somatic obvious risks that may cause an increase in social malfunction of women with depression.Material and methodsRetrospective-prospective study on a sample of 206 female patients, with positive history for depressive disorder, hospitalized in the Mental Health Center (MHC) of Craiova, monitored between January, 1st 2012 and June, 31st 2012. At these patients we evaluated depression evolution, somatic comorbidities, cognitive impairment and psychosocial stress.ResultsSomatic comorbidities (obesity and cardiovascular disease, 41 patients - 19.9%, obesity and diabetes and metabolic syndrome, 36 patients - 17.5%, hysterectomy, 35 patients - 17.5%) occurred during maintenance therapy emphasizes evolutionary risk of depressive disorder in women and cognitive impairment, especially in peri- and postmenopausal period (68.6%). Appeared in a large number of cases of the syndrome MCI (Mild Cognitive Impairment) (29 patients - 14.1%) and 4 cases of Alzheimer's disease also increase the predictive value of perimenopausal depression and psychostress conditions (13.1%).ConclusionsVulnerability to depression is correlated with peri- and postmenopausal ovarian steroid imbalance favoring the disruption of brain neurotransmission. Excess of serotonin activating substance therapy may promote the emergence of hypodopaminergy with risk of increased somatic and cognitive deficiency. Hypodopaminergy conduced to an increased glutamatergic activity, with significant decreases in neuroprotection and neurodegenerative risk.
1594 – Effects Of Alcohol Hangover On Driving Performance
Authors: Verster J.C. , Bervoets A.C. , de Klerk S. , Vreman R.A. , Olivier B. , Brookhuis K.A. 
Published: July 2013

IntroductionAlcohol hangover is the most commonly experienced next day consequence of heavy drinking. The symptoms experienced during this post-intoxication state develop when blood alcohol concentration (BAC) returns to zero. The feeling of general misery can persist up to 24 h and can significantly affect planned activities and cognitive functioning.ObjectiveTo examine the effects of alcohol hangover on driving performance.MethodsIn N=47 healthy volunteers, driving performance was tested the morning following heavy drinking (alcohol hangover) and on a control day (no alcohol). Subjects performed a standardized 100-km highway driving test in the STISIM driving simulator. Primary outcome measure was the Standard Deviation of Lateral Position (SDLP), i.e. the weaving of the car. In addition, self-reported driving quality and driving style measures were scored.ResultsDriving performance was significantly worse during alcohol hangover (ΔSDLP = +1.85 cm; p=0.005). Driving impairment during alcohol hangover was supported by subjective measures. During alcohol hangover, driving quality was rated as significantly worse (p=0.0001), less safe, less considerate, less predictable, and less responsible (p=0.001). Subject reported being significantly more tensed during hangover and more effort was needed to perform the driving test (p=0.001).ConclusionDriving is significantly impaired during alcohol hangover. The magnitude of driving impairment is higher than that observed after administering alcohol to achieve a BAC of 0.05% (ΔSDLP = +1.7 cm), i.e. the legal limit for driving in many countries.
1595 – The Effects Of Mixing Alcohol With Caffeinated Beverages On Subjective Intoxication
Authors: Verster J.C. , de Haan L. , Benson S. , Alford C. , Scholey A. 
Published: July 2013

IntroductionIt has been suggested that mixing alcohol with energy drinks (AMED) and other caffeinated beverages may alter the awareness of intoxication. The proposed reduction in subjective intoxication, also called “the masking effect”, may have serious consequences by increasing the likelihood of engaging in potentially dangerous activities such as driving while intoxicated.AimThe aim of this meta-analysis was to determine if mixing alcohol with caffeinated beverages alters subjective intoxication.MethodsA literature search was conducted (August 21st, 2012) to collect all studies measuring subjective intoxication after administration of AMED, or other caffeinated alcoholic drinks compared to alcohol only. To this extent, PubMed and Embase were searched using the key words “alcohol”, “caffeine”, “energy drinks” and “intoxication”. The studies were critically reviewed and, where possible, included in a meta-analysis in order to determine whether masking exists after mixing alcohol with caffeinated beverages.ResultsTwelve studies were identified of which 8 could be used for the meta-analysis. When including higher caffeine doses (4 mg/kg) the meta-analysis revealed no significant masking effect (p= 0.477). Similarly, when including lower caffeine doses (2 mg/kg) no significant masking effect was found (p=0 .434). Despite the large range of caffeine content (46 - 383 mg) and alcohol levels (0.03% - 0.12% BAC) investigated, caffeine had no effect on the correct judgment of subjective intoxication.ConclusionMixing alcohol with energy drink or other caffeinated beverages does not alter subjective intoxication.