bluuebunny/crossref_metadata_2025_split huggingface dataset:
Naproxen affects osteogenesis of human mesenchymal stem cells via regulation of Indian hedgehog signaling molecules
Authors: Salem Omar , Wang Hong Tian , Alaseem Abdulrahman M , Ciobanu Ovidiu , Hadjab Insaf , Gawri Rahul , Antoniou John , Mwale Fackson 
Published: July 2014

Abstract
Introduction
We previously showed that type X collagen, a marker of late stage chondrocyte hypertrophy (associated with endochondral ossification), is constitutively expressed by mesenchymal stem cells (MSCs) from osteoarthritis patients and this may be related to Naproxen (Npx), a nonsteroidal anti-inflammatory drug used for therapy. Hedgehog (HH) signaling plays an important role during the development of bone. We tested the hypothesis that Npx affected osteogenic differentiation of human MSCs through the expression of Indian hedgehog (IHH), Patched-1 (PTC1) and GLI family members GLI1, GLI2, GLI3 in vitro.

Methods
MSCs were cultured in osteogenic differentiation medium without (control) or with 0.5 μM Npx. The expression of collagen type X, alpha 1 (COL10A1), alkaline phosphatase (ALP), osteopontin (OPN), osteocalcin (OC), collagen type I, alpha 1 (COL1A1) was analyzed with real-time reverse transcription (RT) PCR, and the ALP activity was measured. The osteogenesis of MSCs was monitored by mineral staining and quantification with alizarin red S. To examine whether Npx affects osteogenic differentiation through HH signaling, the effect of Npx on the expression of IHH, GLI1, GLI2, GLI3 and PTC1 was analyzed with real-time RT PCR. The effect of cyclopamine (Cpn), a HH signaling inhibitor, on the expression of COL10A1, ALP, OC and COL1A1 was also determined.

Results
When MSCs were cultured in osteogenic differentiation medium, Npx supplementation led to a significant decrease in ALP gene expression as well as its activity, and had a tendency to decrease mineral deposition. It also decreased the expression of COL1A1 significantly. In contrast, the gene expression of COL10A1 and OPN were upregulated significantly by Npx. No significant effect was found on OC expression. The expression of IHH, PTC1, GLI1, and GLI2 was increased by Npx, while no significant difference was observed on GLI3 expression. Cpn reversed the effect of Npx on the expression of COL10A1, ALP, OPN and COL1A1.

Conclusions
These results indicate that Npx can affect gene expression during osteogenic differentiation of MSCs, and downregulate mineral deposition in the extracellular matrix through IHH signaling. Therefore, Npx could affect MSC-mediated repair of subchondral bone in OA patients.
Designed Electrochemical and Wet-chemical Fabrication of Cu/Cu2O@TiO2 Hybrid Nanowire Arrays for Li-ion Microbattery
Authors: Wu Xiaomeng , Zhang Shichao , Fang Hua , Du Zhijia , Lin Ruoxu 
Published: July 2014

Abstract
Well-organized Cu/Cu2O@TiO2 hybrid nanowire arrays are fabricated by a facile strategy combining the template-directed deposition and in situ template-sacrificial reaction. With an ideal geometrical configuration, the prepared nanoelectrodes exhibit superior rate capability with enhanced areal capacity when used as anode materials for reversible Li+ storage.
Total Syntheses of (+)-Sesamin and (+)-Sesaminol
Authors: Ishikawa Ryo , Yoshida Naoto , Akao Yusuke , Kawabe Yusuke , Inai Makoto , Asakawa Tomohiro , Hamashima Yoshitaka , Kan Toshiyuki 
Published: July 2014

Abstract
Total syntheses of (+)-sesamin (1a) and (+)-sesaminol (1b), which are major components of sesame lignans derived from Sesamum indicum, were accomplished in a highly stereocontrolled manner. Key steps include an l-proline-catalyzed cross-aldol reaction, which was accelerated with the aid of bifunctional urea 7, and the construction of a furofuran lignan skeleton through a quinomethide intermediate.
A New Solution for the Moral Hazard Problem in Team Production
Authors: Guillen Pablo , Merrett Danielle , Slonim Robert 
Published: July 2014

We propose an intergroup competition scheme (ICS) to theoretically solve free riding in team production and provide experimental evidence from a voluntary contribution mechanism public goods game. The ICS includes an internal transfer payment from the lowest to highest contributing team proportional to the difference in group contributions. The ICS requires minimal information, makes the efficient contribution a dominant strategy, and is budget balanced. These features make the ICS ideally suited to solve the moral hazard problem in team production. Our experiment demonstrates that the ICS raises contributions to almost reach optimality with the appropriate parameters. We also show experimentally that the success of the ICS can be primarily attributed to the effect of higher returns and to the introduction of competition, and it is not due to the introduction of potential losses or information regarding other groups. Data, as supplemental material, are available at http://dx.doi.org/10.1287/mnsc.2014.1922 . This paper was accepted by Uri Gneezy, behavioral economics.
Percutaneous Gastrojejunostomy under Fluoroscopic Guidance: Results from a Single Center in a Cohort of 23 Consecutive Patients
Authors: Grasso Rosario Francesco , Cazzato Roberto Luigi , Faiella Eliodoro , Schena Emiliano , Del Vescovo Riccardo , Giurazza Francesco , Mercurio Simona , Luppi Giacomo , Zobel Bruno Beomonte 
Published: July 2014

Introduction: to retrospectively investigate technical success, clinical success, complication rate, tube patency and 30-day mortality in a population of patients receiving percutaneous gastro-jejuonostomy (PGJ) under fluoroscopic guidance. Method: Institutional review board was obtained for the present study. Twenty-three patients (11 male, 12 female; mean age 68.3 years, range 37-95 years) were included. Descriptive statistics was used to investigate all variables and tube patency was investigated with Kaplan-Myer plot during a 4-month period. Results: Twenty-three PGJs were placed during a 3-year period in 23 consecutive patients. Technical success for PGJ first placement was reached in 22 patients (95.6%). PGJ exchange was always successful. Clinical success was always reached (100%) after each single procedure. We registered two cases of major complications consistent with bleeding requiring interventions. Minor complications encountered during follow-up were tube clogging and superficial stomal infection. Four-months tube patency was 76.5%. Overall 30-day mortality was 17.4% and 30-day PGJ related mortality was 0%. Conclusion: PGJ under fluoroscopic guidance is a safe and effective procedure with high rates of technical and clinical success coupled to low rates of complications and mortality.
Study of Low-Pressure Argon Adsorption on Synthetic Nontronite: Implications for Smectite Crystal Growth
Authors: Decarreau Alain , Petit Sabine , Andrieux Pauline , Villieras Frederic , Pelletier Manuel , Razafitianamaharavo Angelina 
Published: July 2014

AbstractBecause relatively little information about the crystal-growth process of smectite is available, the process was assessed here by studying the size and shape of nontronite particles synthesized at six different temperatures from 75 to 150°C over a period of 4 weeks.The morphology of nontronites was studied using low-pressure isotherms of argon adsorption at 77 K, a method which enables the measurement of the basal and edge surface areas of the nontronite particles and of their mean diameter and thickness. During the crystal growth of nontronite, the mean particle length increased whereas their thickness (and the number of stacked layers) did not vary significantly.A specific two-dimensional crystal-growth process was observed for smectite via the lateral extension of the layers. This process also appears to occur during the growth of neoformed natural smectite.
Stability of Iron in Clays Under Different Leaching Conditions
Authors: Dousova Barbora , Fuitova Lucie , Kolousek David , Lhotka Miloslav , Grygar Tomas Matys , Spurna Petra 
Published: July 2014

AbstractThe iron chemistry of aluminosilicates can markedly affect their adsorption properties due to possible changes in surface charge upon exposure to a variety of processes in the environment. One of these processes is chemical leaching, but to date little has been reported on the susceptibility of structural Fe to chemical leaching. The purpose of the current study was to determine the effects of solution pH on the stability of structural Fe in kaolinites, illite, and bentonite and the potential for formation of ancillary (oxyhydr)oxides. Structurally bound Fe does not participate in sorption properties but Fe that is released and phase transformed during leaching could take part in adsorption processes and form complexes and/or covalent bonds via Fe ions. Five different Fe-bearing clay minerals were treated in 0.5 M and 2 M HCl, distilled H2O, 0.1MKCl, and 0.5MKHCO3 for 24 h. The amount of Fe leached varied from 10 μg g-1 (for 0.1 M KCl) to 104 μg g-1 (for 2 M HCl) depending on the leaching agents. Acidic and water treatments indicated a relative independence of leached Fe on the initial Fe content in the clay and, conversely, a heavy dependence on the crystallinity of initial Fe phases. Well crystallized Fe(III) was stable during the leaching process, while poorly crystallized and amorphous Fe(III) phases were less stable, forming new ion-exchangeable Fe3+ particles. Under alkaline conditions, no relation between Fe crystallinity and mobility was found. The structural and surface changes resulting from leaching processes were identified by equilibrium adsorption isotherms. In kaolinite, the specific surface area (SBET) and porosity changed independently of Fe leaching due to the stability and crystallinity of Fe. In bentonite, the number of micropores was reduced by their partial saturation with Fe3+ particles caused by poorly crystallized and more reactive Fe forms during the leaching process. Potential phase transformations of Fe were characterized by the voltammetry of microparticles; well crystallized Fe(III) oxides remained stable under leaching conditions, while poorly crystallized and amorphous Fe(III) phases were partially dissolved and transformed to reactive Fe3+ forms.
First Principles Ab Initio Study of CO2 Adsorption on the Kaolinite (001) Surface
Authors: He Man-Chao , Zhao Jian , Li Yang 
Published: July 2014

AbstractThe capture and storage of carbon dioxide (CO2) have considerable potential for mitigating climate change. Adsorption is one of the most popular methods for the storage of CO2. The adsorption of CO2 molecules on the hydroxylated (001) surface of kaolinite was investigated using density-functional theory within the generalized gradient approximation and a supercell approach. The coverage dependence of the adsorption structures and energetics was studied systematically for a wide range of coverage, Θ [from 0.11 to 1.0 monolayers (ML)], and adsorption sites. The CO2 was adsorbed on the two-fold bridge-x (see the text for a definition) and the one-fold top-x sites in the bent, recumbent configuration, and on the three-fold hollow-z, two-fold bridge-z site, and the one-fold top-z sites in the vertical configuration. The surface-adsorbed binding site of CO2 was strongest at the bridge-x site and weakest at the top-z site. The adsorption energy increased with coverage, thus indicating the greater stability of surface adsorption and a tendency to form CO2 islands (clusters) with increasing coverage. The other properties of the CO2/kaolinite (001) system, including the different charge distribution, the lattice relaxation, and the electronic density of states, were also studied and are discussed in detail.
From Beijing with love: The global dimension of Bertolucci’s The Last Emperor
Authors: Baschiera Stefano 
Published: July 2014

Abstract
Famous for being the first foreign feature film that obtained permission to shoot in the Forbidden City, The Last Emperor (1987) is also one of the most ambitious and expensive independent productions of its time, awarded four Golden Globes and nine Academy Awards, including Best Picture. In addition, The Last Emperor can be considered as one of the first attempts of cinematic collaboration between West and East, in a period of cultural and economic transformations witnessed by China. This article aims to offer an overview of the production history of The Last Emperor, focusing on the co-production collaborations and the outcomes of a western auteur’s gaze on Chinese history. Questions of Orientalism, travel narrative and critical reception are taken into account in order to engage with the transnational implications of Bertolucci’s film and the western fascination with China.
New hosts and distribution records of Braga patagonica, a parasite cymothoidae of fishes from the Amazon
Authors: Tavares-Dias Marcos , Araújo Cleuza Suzana Oliveira , Barros Márcia Souza , Viana Gabriela Moraes 
Published: July 2014

Specimens of Braga patagonica SchiÃ¶dteÂ &Â Meinert,Â 1884Â (Isopoda: Cymothoidae) from freshwater fishes deposited in Ichthyological Collection of Amazon National Research Institute (INPA), in central Amazon and from fishes from eastern Amazon (Brazil) were investigated. Prevalence, infection intensity and body measures of B. patagonicafor different populations of this cymothoid in wild fishes species from Amazon were carried out. Four species of Serrasalmidae, one Characidae, one Cichlidae, one Cynodontidae, one Curimatidae, one Acestrorhynchidae and one Sciaenidae were recorded as new hosts for B. patagonicain the Amazon. This study indicates a low intensity and low parasitic specificity of B. patagonica, and also recorded the first parasitism by this ectoparasite in farmed Colossoma macropomum, describing its highly pathogenic effect.
Pricing of First-Run Movies in Small U.S. Metropolitan Areas: Multimarket Contact and Chain Effects
Authors: Feinberg Robert M. 
Published: July 2014

Abstract
In recent years, the role of multimarket contact (MMC) among firms in influencing market performance has been studied for a relatively small group of industries – with banking and airlines most often examined, though the cement and telecommunications industries have been studied as well. This paper investigates this issue for the local movie theater industry in the U.S., one not previously studied in this regard. In small U.S. metropolitan areas, there is considerable variation in the nature of MMC among theater chains (large and small), which allows us to examine whether MMC among firms has an impact on movie pricing in these smaller markets. Data on movie pricing, market structure, and income and population characteristics are obtained for 118 multi-screen first-run movie theaters in 79 small metropolitan areas – those with under 250,000 people – which are not part of larger “consolidated” metropolitan areas. Analysis provides evidence supportive of MMC effects but suggestive of its limited applicability.
On Run-preventing Contract Design
Authors: Ohashi Yoshihiro 
Published: July 2014

AbstractThis study considers how to implement an efficient allocation of a financial intermediation model, including liquidation costs. The main result shows that there is a mechanism such that, for any liquidation cost, an efficient allocation is implementable in strictly dominant strategies. There is no need for third-party assistance, such as deposit insurance. In addition, the mechanism is tolerant of a small, unexpected shock caused by premature withdrawals.
Liver rupture in HELLP syndrome
Authors: Jungfleisch Katrin , Fittschen Monica , Rapp Hans-Jürgen , Schäfer Henry , Bahlmann Franz 
Published: July 2014

Abstract
We report on a 30-year-old Caucasian woman admitted to our clinic after 34 weeks of gestation because of a severe partial hemolysis, elevated liver enzymes, low platelets (HELLP) syndrome. A cesarean section was performed when her clinical symptoms and laboratory values worsened. Intraoperatively she was diagnosed with hepatic subcapsular hematoma and liver rupture. Surgical treatment, including perihepatic packing with sterile towels removed 2 days post-surgery, resulted in an uneventful recovery. The patient was discharged 26 days after admission. Case reports such as ours may contribute to the management of pregnancies complicated by hepatic hematoma and rupture of the liver capsule associated to HELLP syndrome.
Medicare Reimbursement Reform for Provider Visits and Health Outcomes in Patients on Hemodialysis
Authors: Erickson Kevin F. , Winkelmayer Wolfgang C. , Chertow Glenn M. , Bhattacharya Jay 
Published: July 2014

AbstractThe relation between the quantity of many healthcare services delivered and health outcomes is uncertain. In January 2004, the Centers for Medicare and Medicaid Services introduced a tiered fee-for-service system for patients on hemodialysis, creating an incentive for providers to see patients more frequently. We analyzed the effect of this change on patient mortality, transplant wait-listing, and costs. While mortality rates for Medicare beneficiaries on hemodialysis declined after reimbursement reform, mortality declined more – or was no different – among patients whose providers were not affected by the economic incentive. Similarly, improved placement of patients on the kidney transplant waitlist was no different among patients whose providers were not affected by the economic incentive; payments for dialysis visits increased 13.7% in the year following reform. The payment system designed to increase provider visits to hemodialysis patients increased Medicare costs with no evidence of a benefit on survival or kidney transplant listing.
„Aus der Krankheit konnten wir unsere Waffe machen.“
Authors: Köppen Paul 
Published: July 2014

Vorspann
War die restriktive Finanz- und Haushaltspolitik der von Heinrich Brüning zwischen 1930 und 1932 geführten Präsidialkabinette alternativlos? Oder hätte es Handlungsspielräume für einen anderen Kurs gegeben, um die sozialen und ökonomischen Folgen der Weltwirtschaftskrise zumindest abzumildern? Über diese Fragen ist viel diskutiert worden, und sie stehen auch im Mittelpunkt des Aufsatzes von Paul Köppen. Der Historiker nähert sich der Thematik am Beispiel der französischen Kreditangebote auf dem Höhepunkt der Krise, arbeitet davon ausgehend Brünings langfristige Ziele heraus und kommt schließlich zu einer eindeutigen Antwort.
Volksgemeinschaft und die Gesellschaftsgeschichte des NS-Regimes
Authors: Steber Martina , Gotto Bernhard , Föllmer Moritz , Longerich Peter , Süß Dietmar , Harvey Elizabeth 
Published: July 2014

Vorspann
Taugt Volksgemeinschaft als analytischer Leitbegriff einer erneuerten Gesellschaftsgeschichte des „Dritten Reiches“? Über kein anderes Thema wird in der NSForschung seit Jahren heftiger diskutiert. Ihren Höhepunkt erreichte die Kontroverse 2010 auf einer internationalen Konferenz am Deutschen Historischen Institut London, deren Ergebnisse der Sammelband „Visions of Community in Nazi Germany. Social Engineering and Private Lives“ (Oxford 2014) bündelt. Martina Steber und Bernhard Gotto, die Herausgeber des Werkes, werben für die Innovationskraft des Zugangs und synthetisieren aus den Diskussionsbeiträgen ein Modell, das den Begriff der Volksgemeinschaft operationalisiert. Moritz Föllmer, Elizabeth Harvey, Peter Longerich und Dietmar Süß diskutieren seine Vorzüge und Grenzen, zeigen zugleich aber auch auf, dass der vielversprechende gesellschaftsgeschichtliche Zugriff den großen Praxistest noch bestehen muss.
Thickness Dependent Photoelectrochemical Performance of Chemo-Synthesized Nanostructured CdS Thin Films
Authors: Vanalakar Sharadrao A. , Mali Sawanta S. , Suryawanshi Mahesh P. , Tarwal Nilesh L. , Agawane Ganesh L. , Gurav Kishor V. , Shin Seung W. , Moholkar Annasaheb V. , Kim Jin H. , Patil Pramod S. 
Published: July 2014

Abstract
Thin films of cadmium sulfide (CdS) with different film thicknesses
were chemo-synthesized onto soda lime glass and fluorine doped tin
oxide (FTO) coated glass substrates. The synthesized CdS films were
characterized by using UV-vis spectroscopy, X-ray diffraction (XRD),
scanning electron microscopy (SEM) and atomic force microscopy
(AFM). The XRD patterns revealed the formation of CdS with a cubic
crystal structure. The variation in band gap energies was found to be
in the range of 2.42–2.85 eV. An increase of
0.43 eV over the bulk band gap energy of CdS was found due
to the quantum size effect in CdS thin films. The atomic force
microscopy study depicted a novel egg-like morphology of CdS
nanoparticles. Further, photoelectrochemical (PEC) performance of as
grown CdS thin films was investigated using two electrode
configurations in polysulfide electrolyte. The sample with film
thickness 1389 Å showed the best PEC performance
compared to other samples.
Ptychographic X-ray Microscopy with the Vacuum Imaging Apparatus HORST
Authors: Gorniak Thomas , Rosenhahn Axel 
Published: July 2014

Abstract
Imaging is one of the key drivers for new scientific insights – from
the observation of distant stars in astronomy to microscopic studies
of sub-cellular structures in biology. In the latter case, X-rays are
a versatile probe due to their small wavelength and thus high spatial
sensitivity. We give an overview of applicable lensless, coherent
imaging approaches relying on scattering with a focus on ptychographic
microscopy and discuss the experimental requirements for the soft
X-ray scattering experiment HORST. Besides the experiment itself, we
highlight the importance of sample environments, especially when
biological specimens are investigated. Here, the water window is of
central importance. In addition to exploitation of the contrast and
resolution, resonant ptychography allows to distinguish chemical
species at high spatial resolution with both phase and amplitude
contrast.
Measurement of Moisture Content with a Penetrometer
Authors: Singh Gurdev , Das Braja M. , Chong M. K. 
Published: July 2014

Abstract
Interpretation and reliability of in situ tests, such as cone penetration, can be improved if in situ moisture content and density can be measured without affecting the speed of site investigation significantly. This paper describes the principle and technique of determining moisture content with a penetrometer that can measure the dielectric constant (specific inductive capacitance) of soils. Effects of various factors, such as salt content of water, on the measured parameter are discussed with special reference to frequency of the measuring bridge. This study shows that it is possible to determine the in situ moisture content of soils from measurements conducted at very high frequencies. This method presents particular promise because the moisture content versus capacitance relationship has been found to be practically independent of soil type.
Rapid Density Profiling of Consolidating Clay Using Synchrotron Radiation
Authors: Charlie Wayne A. , Durnford Deanna , Steenhuis Tammo S. 
Published: July 2014

Abstract
The high-energy, highly collimated X-ray beam at the Cornell High Energy Synchrotron Source (CHESS) was used to provide rapid and high-resolution temporal and spatial density distributions in a consolidating saturated clay specimen. Porewater pressure at the undrained base of the clay was obtained by a porewater pressure transducer. Test results show good agreement between theoretical and experimental density distributions and indicate that synchrotron radiation is a promising and unique method to study consolidation.
Soil Fabric Changes During Consolidation
Authors: Adamcewicz Amy S. , Muhunthan Balasingam , Masad Eyad 
Published: July 2014

Abstract
A method for characterizing the directional distribution of voids in soils at the microstructural level is presented. A scanning electron microscope (SEM) was used to obtain high-resolution, high-magnification images of the soil microstructure. These images were analyzed using an image analysis program to obtain parameters of the directional void ratio distribution function. Useful indices based on both solid and void phases for describing the changes of fabric in soils are proposed, and their evolution under one-dimensional compression of soils is studied. The analyses showed a high degree of preferred orientation attained by soil particles during consolidation.