bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Synthesis of β‐Amino Ketones Containing Organosilicon Groups: Catalytic Enantioselective Three‐Component Mannich‐Type Reaction.
Authors: Safa Kazem D. , Abolfathi Mahtab , Ghorbanpour Khatereh 
Published: March 2013

AbstractWith cyclic ketones (I) or (V), the process affords mixtures of diastereomers where the anti‐isomer is always formed as main component.
ChemInform Abstract: Synthesis of Sulfonamides and Sulfonic Esters via Reaction of Amines and Phenols with Thiols Using H2O2—POCl3 System.
Authors: Bahrami Kiumars , Khodaei Mohammad M. , Abbasi Jamshid 
Published: March 2013

AbstractA highly selective, simple, mild, fast, and clean synthesis of the title compounds is reported by using a commercially available inexpensive catalyst.
ChemInform Abstract: Trimethylsilyl Chloride Promoted Synthesis of α‐Branched Amines by Nucleophilic Addition of Organozinc Halides to Nitrones.
Authors: Fu Ying , Liu Yanhua , Chen Yaojuan , Huegel Helmut M. , Wang Minzhu , Huang Danfeng , Hu Yulai 
Published: March 2013

AbstractThe present new method proceeds in the presence of trimethylsilyl chloride which acts as an essential reaction promoter and a protection reagent for the sensitive N‐hydroxylamine group.
ChemInform Abstract: A Novel Imidazolium‐Supported Palladium—Chloroglycine Complex: Copper‐ and Solvent‐Free High‐Turnover Catalysts for the Sonogashira Coupling Reaction.
Authors: Karthikeyan Parasuraman , Muskawar Prashant Narayan , Aswar Sachin Arunrao , Bhagat Pundlik Rambhau , Sythana Suresh Kumar 
Published: March 2013

AbstractFor the first time the title catalyst is successfully applied to the Sonogashira coupling reaction without the use of an organic co‐solvent.
ChemInform Abstract: Highly Diastereoselective Synthesis of Atropisomeric Bridged P,N‐Ligands and Their Applications in Asymmetric Suzuki—Miyaura Coupling Reaction.
Authors: Qiu Liqin , et al. et al. 
Published: March 2013

AbstractElectron‐withdrawing groups in the boronic acids lead to diminished the yields and enantioselectivities.
ChemInform Abstract: Microwave‐Promoted Suzuki—Miyaura Cross‐Coupling of Aryl Imidazolylsulfonates in Water.
Authors: Civicos Jose F. , Alonso Diego A. , Najera Carmen 
Published: March 2013

AbstractThis is a phosphane‐free Suzuki reaction which uses hexadecyltrimethylammonium bromide as an additive.
ChemInform Abstract: Facile Access to 2,5‐Disubstituted‐4‐chloromethyl‐3‐iodofuran Derivatives via ICI‐Mediated Cyclization of 1‐Alkyl‐2‐alkynylallylic Alcohols.
Authors: Thongsornkleeb Charnsak , Rabten Wangchuk , Bunrit Anon , Tummatorn Jumreang , Ruchirawat Somsak 
Published: March 2013

AbstractThe electrophilic agent I—Cl induces rapid cyclization of secondary enynyl alcohols (I) into dihalofurans (II).
ChemInform Abstract: Highly Enantioselective Alkenylation of Cyclic α,β‐Unsaturated Carbonyl Compounds as Catalyzed by a Rhodium—Diene Complex: Application to the Synthesis of (S)‐Pregabalin and (‐)‐α‐Kainic Acid.
Authors: Yu Hong‐Jie , Shao Cheng , Cui Zhe , Feng Chen‐Guo , Lin Guo‐Qiang 
Published: March 2013

AbstractIn the case of oxygen containing substrates (VII) a change of a base and solvent is required.
ChemInform Abstract: Anion‐Induced Enantioselective Cyclization of Diynamides to Pyrrolidines Catalyzed by Cationic Gold Complexes.
Authors: Mourad Asmaa Kamal , Leutzow Juliane , Czekelius Constantin 
Published: March 2013

AbstractA new method is presented which affords optically active methylene pyrrolidines via cycloisomerization of 1,4‐diynamides under optimized conditions.
ChemInform Abstract: A Novel Route for the Synthesis of 3‐(Pyrrol‐1‐yl)‐indolin‐2‐ones.
Authors: Sarkar Swarbhanu , Saha Bidula , Naskar Subhendu 
Published: March 2013

AbstractA high‐yielding environmentally benign protocol for the synthesis of title compounds (III) using a Lewis acid surfactant catalyst which is crucial for a successful transformation.
ChemInform Abstract: Regioselective Friedel—Crafts Acylation of Indoles Catalyzed by Zinc Oxide in an Ionic Liquid.
Authors: Zhang Li‐Rong , Yi Feng‐Fing , Zou Jian‐Zhong , Zhang Xuan , Wang Zhen 
Published: March 2013

AbstractThe functionalization of (I) occurs regioselectively at the C‐3 position to produce various indole structures of pharmaceutical interest.
ChemInform Abstract: A New and Efficient Domino Strategy to Indole Derivatives Synthesis and Its C3‐Bisfunctionalization.
Authors: Xue Li‐Yuan , Jiang Bo , Tu Man‐Su , Tu Shu‐Jiang 
Published: March 2013

AbstractThe construction of C3‐difunctionalized indoles (III) is readily achieved through metal‐free ring opening of alloxan monohydrate (II) with enaminones (I).
ChemInform Abstract: Highly Substituted Pyrazoles and Pyridazines by MIRC Reactions of Hydrazone Anions and Nitrobutadienic Fragments.
Authors: Bianchi Lara , Carloni‐Garaventa Alessandro , Maccagno Massimo , Petrillo Giovanni , Scapolla Carlo , Tavani Cinzia 
Published: March 2013

AbstractDifferent approaches are investigated to the pharmaceutically interesting heterocyclic systems.
ChemInform Abstract: Synthesis and Biological Evaluation of Novel Pyrazole Derivatives as Antibacterial Agents.
Authors: Daemi Fariba , Allameh Sadegh , Pordel Mehdi 
Published: March 2013

AbstractConcerning the antibacterial activity against MRSA, derivatives (VIc) and (VIe) display promising potency in the range of cephalexin, cloxacillin, and erythromycin.
ChemInform Abstract: π‐Annulation Reactions of 4‐Thiazolidinone Enaminones in the Synthesis of Fused Bi‐ and Tri‐Cyclic Compounds.
Authors: Bondzic Bojan P. , Dzambaski Zdravko , Bondzic Aleksandra M. , Markovic Rade 
Published: March 2013

AbstractAn easy and efficient route for the synthesis of various bi‐and tricyclic thiazolidines is developed using π‐annulation reactions as the key step.
ChemInform Abstract: Synthesis of 2,3‐Dihydro‐4‐pyranones from Epoxides via Intermolecular [4 + 2] Cycloaddition Reaction.
Authors: Indukuri Kiran , Bondalapati Somasekhar , Sultana Sabera , Saikia Anil Kumar 
Published: March 2013

AbstractThe title reaction can be applied to various epoxides and cyclobutanones.
ChemInform Abstract: Practical Pd/C‐Catalyzed Suzuki—Miyaura Reactions for the Preparation of 3‐Aryl‐4‐oxypyridin‐2(1H)‐ones, 3‐Aryl‐2,4‐oxypyridines and 3‐Aryl‐2,4‐oxyquinolines as Useful Intermediates for the Synthesis of Biologically Active Compounds.
Authors: Lamblin Marc , Bares Hugo , Dessolin Jean , Marty Christel , Bourgougnon Nathalie , Felpin Francoise‐Xavier 
Published: March 2013

AbstractThe reaction products can be further transformed into antiviral nucleosides.
ChemInform Abstract: Spiroazetidine—Piperidine Bromoindan as a Key Modular Template to Access a Variety of Compounds via C—C and C—N Bond‐Forming Reactions.
Authors: Orr Suvi T. M. , et al. et al. 
Published: March 2013

AbstractIn connection with a research concerning novel ghrelin inverse agonists, the use of (I) in several Pd‐catalyzed coupling reactions is examined.
ChemInform Abstract: Ag(I)‐Catalyzed Aminofluorination of Alkynes: Efficient Synthesis of 4‐Fluoroisoquinolines and 4‐Fluoropyrrolo[α]isoquinolines.
Authors: Xu Tao , Liu Guosheng 
Published: March 2013

AbstractRelated compounds such as (IV), (VI), and (XII) are also available.
ChemInform Abstract: Modular Synthesis of Phenanthridine Derivatives by Oxidative Cyclization of 2‐Isocyanobiphenyls with Organoboron Reagents.
Authors: Tobisu Mamoru , Koh Keika , Furukawa Takayuki , Chatani Naoto 
Published: March 2013

AbstractThe reaction involves a homolytic aromatic substitution by aryl or alkyl radicals, generated from boronic acids and manganese salt.
ChemInform Abstract: Selective Palladium‐Catalyzed Direct Arylation of Furo[3,2‐b]pyridines.
Authors: Carrer Amandine , Rousselle Patricia , Florent Jean‐Claude , Bertounesque Emmanuel 
Published: March 2013

AbstractThis describes the two‐step diarylation of furo[3,2‐b]pyridines in positions 3 and 7.
ChemInform Abstract: Point‐to‐Helical Chirality Transfer for a Scalable and Resolution‐Free Synthesis of a Helicenoidal DMAP Organocatalyst (III).
Authors: Crittall Matthew R. , Fairhurst Nathan W. G. , Carbery David R. 
Published: March 2013

Abstractvia a diastereoselective Rh‐catalyzed triyne cycloisomerization
ChemInform Abstract: Solvent and Substituent Effects on the Electronic Spectra of 3‐Arylazo‐imidazo[1,2‐b]pyrazolo[4,3‐d]pyridazines.
Authors: Shawali Ahmad S. , Farghaly Thoraya A. , Nawar Tarek M. S. 
Published: March 2013

AbstractThe solvatochromic and substituent effects on the absorption spectra of azo dyes (III) are interpreted by correlation of absorption frequencies with Kamlet—Taft and Hammet equations, respectively.
ChemInform Abstract: Synthesis and Antimicrobial Activity Studies of Certain Pyrimidinyl Oxadiazolo Azetidinones.
Authors: George Sonia , Sabitha R. , Govindhammal V. , Ravi T. K. 
Published: March 2013

AbstractThe antibacterial screening reveals that compounds (VIIIb), (VIIId) and (VIIIe) show good activities against M.lutues and P.aeruginosa.
ChemInform Abstract: Synthesis, Antimicrobial and Antioxidant Activities of Some Indole Analogues Containing Naphthyridine and Pyrimidonaphthyridine Systems.
Authors: Saudane Anand R. , Prabhaker Walmik 
Published: March 2013

AbstractA variety of the title naphthyridine derivatives (V) are synthesized and transformed into pyrimidonaphthyridine systems (VII), (IX), (XI) via reactions with formic acid, carbon disulfide and formamide, respectively.
ChemInform Abstract: Synthesis of Functionalized Benzimidazoles and Quinoxalines Catalyzed by Sodium Hexafluorophosphate Bound Amberlite Resin in Aqueous Medium.
Authors: Ghosh Pranab , Mandal Amitava 
Published: March 2013

AbstractResin‐bound hexafluorophosphate is found to be a greener and more efficient catalyst for the title reaction than NaPF6 itself.
ChemInform Abstract: Synthesis of Azepine Derivatives by Rhodium‐Catalyzed Tandem 2,3‐Rearrangement/Heterocyclization.
Authors: Nakamura Itaru , Okamoto Masashi , Sato Yoshinori , Terada Masahiro 
Published: March 2013

AbstractOptimized conditions are developed for the reaction of (Z)‐ or (E)‐O‐propargylic cyclopropylcarbaldoximes (I) or (III) to furnish the desired azepine oxides with exclusive (Z) configuration at the alkylidene site.
ChemInform Abstract: A Facile Synthesis of 3,5,7‐Trisubstituted‐4H‐[1,2]diazepines by Microwave Irradiation.
Authors: Manih Rudolf Manton , Myrboh Bekington 
Published: March 2013

AbstractA simple and convenient method for the synthesis of the title diazepines (IV) (16 examples) is developed using a microwave‐assisted condensation of α,β‐unsaturated 1,5‐diketones (III) with hydrazine derivatives.
ChemInform Abstract: Behavior of β‐Keto‐δ‐carbethoxyphosphonates and Phosphine Oxides in the Biginelli Multicomponent Reaction: Regioselective Synthesis of 5‐Carbethoxy‐6‐phosphonomethyl‐3,4‐dihydropyrimidin‐2‐ones.
Authors: Chebil Emna , Touil Soufiane 
Published: March 2013

AbstractThe title compounds are efficiently and regioselectively obtained in an efficient one‐pot three‐component Biginelli‐type condensation of phosphine oxides (I) with aldehydes (II) and urea (III) using AcOH as catalyst.
ChemInform Abstract: Conversion of Two Eremophilane Glucosides from Pittocaulon praecox into Eremophilanolides.
Authors: Arcinegas Amira , Maldonado Jhon Ironzi , Perez‐Castorena Ana‐L. , Romo de Vivar Alfonso 
Published: March 2013

AbstractAcid treatment of eremophilanes (I), (V) leads to eremophilanoids (II), (III), an aldehyde (IV), the intramolecular addition product (VI), and the water addition products (VII) and (VIII).
ChemInform Abstract: An Expedient Approach to the Total Synthesis of (+)‐5‐epi‐Eudesm‐4(15)‐ene‐1β,6β‐diol.
Authors: Parthasarathy Gowrisankar , Besnard Celine , Kuendig E. Peter 
Published: March 2013

AbstractThe title compound (V) is synthesized via an Ireland—Claisen rearrangement of glycolate ester (I) and an intramolecular nitrile oxide cycloaddition [→ (IV)] as key steps.
ChemInform Abstract: Triterpene Constituents and Antibacterial Activity of the Stems of Reissantia grahamii.
Authors: Patra Amarendra , Ghosh Sumana , Bandyopadhyay Sajal Kumar , Bag Prasanta Kumar , Bhowmik Poulami , Sukumar Ethirajan 
Published: March 2013

AbstractNew triterpenoid (I), named reissantiadiol, is isolated among known compounds from the stems of reissantia grahamii.
ChemInform Abstract: Synthesis and in vitro Antitumor Screening of 2‐(β‐D‐xylofuranosyl)thiazole‐4‐carboxamide and Two Novel Tiazofurin Analogues with Substituted Tetrahydrofurodioxol Moiety as a Sugar Mimic.
Authors: Popsavin Mirjana , Spaic Sasa , Svircev Milos , Kojic Vesna , Bogdanovic Gordana , Popsavin Velimir 
Published: March 2013

AbstractThe known thiazofurin stereoisomer (VII) and two new thiazofurin analogues (XI) and (XII) are synthesized and evaluated for their in vitro antitumor activity.
ChemInform Abstract: Antiphospholipid Antibody Profiling — Time for a New Technical Approach?
Authors: Roggenbuck Dirk , Egerer Karl , von Landenberg Philipp , Hiemann Rico , Feist Eugen , Burmester Gerd‐Ruediger , Doerner Thomas 
Published: March 2013

AbstractReview: 67 refs.
Synthesis of Porous Carbon Monoliths by Using Porous Concrete as Template
Authors: Günther David , Klepel Olaf 
Published: March 2013

AbstractÜber eine templatgestützte Methode wurden hochporöse Kohlenstoffmonolithe unter Verwendung von Porenbeton als Templat hergestellt. Aufgrund der guten mechanischen Bearbeitbarkeit von Porenbeton lassen sich poröse Kohlenstoffmonolithe in vielfältiger Form synthetisieren. Die Porenweitenverteilung der erhaltenen Monolithe erstreckt sich vom Mikro‐ bis zum Makroporenbereich. Derartige Materialien stellen eine vielversprechende Basis für die Entwicklung von technischen Komponenten für den Einsatz in Adsorption oder Katalyse dar.
Chiral Sulfinamide‐Olefin Ligands: Switchable Selectivity in Rhodium‐Catalyzed Asymmetric 1,2‐Addition of Arylboronic Acids to Aliphatic α‐Ketoesters
Authors: Zhu Ting‐Shun , Xu Ming‐Hua 
Published: March 2013

AbstractSimple and readily available chiral N‐(sulfinyl)allylamines have been developed as efficient novel ligands for the rhodium‐catalyzed enantioselective 1,2‐addition of arylboronic acids to challenging aliphatic α‐ketoesters. By employing the linear or branched sulfinamide‐olefin ligands, interesting enantioselectivity as well as regioselectivity reversal in the related asymmetric additions were observed.
Thyroglobulin measurements in fine‐needle aspiration cytology of lymph nodes for the detection of metastatic papillary thyroid carcinoma
Authors: Li Qing Kay , Nugent Summer L. , Straseski Joely , Cooper David , Riedel Stefan , Askin Frederic B. , Sokoll Lori J. 
Published: March 2013

BACKGROUNDUltrasound‐guided fine‐needle aspiration (US‐FNA) cytology is a commonly used method in the surveillance of suspicious lymph nodes (LNs) in patients with papillary thyroid carcinoma (PTC). The measurement of thyroglobulin (Tg) levels in LNs during FNA has been suggested to improve the diagnosis. In the current study, the use of US‐FNA‐Tg in LNs that were suspicious for metastatic PTC was investigated.METHODSA total of 208 cases from the Johns Hopkins Hospital with both US‐guided FNA cytology and US‐FNA‐Tg measurements were included; 60 cases had follow‐up surgeries performed. Tg levels were correlated with cytological and histological diagnoses.RESULTSOf 35 cases of cytologically diagnosed metastatic PTC, 34 were confirmed by surgery. The median US‐FNA‐Tg concentration was 4232.7 ng/mL, whereas in 112 benign LNs the median Tg concentration was < 0.2 ng/mL (P < .0001). Receiver operating characteristic analysis (area under the curve, 0.949) demonstrated a sensitivity of 97% and a specificity of 81% at the Tg detection limit (<0.2 ng/mL), whereas cutoff values of 9.6 ng/mL to 100 ng/mL resulted in a sensitivity of 76% and a specificity of 98%. Of 15 cases with a cytological diagnosis of “suspicious for PTC,” 9 cases had markedly elevated Tg levels detected on FNA. Seven of these 9 cases had follow‐up surgeries confirming the diagnosis of PTC. Of 29 cases with a “nondiagnostic” cytology, 7 had markedly elevated Tg levels on FNA, with a median of 1305.5 ng/mL, and were confirmed to be metastatic PTC at surgery.CONCLUSIONSUS‐FNA‐Tg demonstrated a strong negative predictive value (93%‐99%). It may be particularly useful for difficult cases. However, standardization of the sample collection is still needed to further improve the accuracy of the approach. Cancer (Cancer Cytopathol) 2013;121:440‐8. © 2013 American Cancer Society.
A neutron diffraction study of the phase transition of fully deuterated triglycine sulphate (ND2CD2COOD)3.D2SO4
Authors: Hudspeth J. M. , Goossens D. J. , Gutmann M. J. , Studer A. J. 
Published: March 2013

AbstractUsing neutron single crystal and powder diffraction, the first thorough investigation of the structure of fully deuterated triglycine sulphate, (ND2CD2COOD)3.D2SO4 is presented, including its evolution with T, through its structural phase transition. This includes new precise structural parameters determined at several key temperatures above and below TC using single crystal diffraction, and for the first time a parametric study has been undertaken over a wide temperature range — from 4 to 500 K in 2 K steps. It was found that fully deuterated TGS shows a structure consistent with hydrogenous TGS and partially deuterated TGS. The evolution of several key hydrogen bond lengths suggests that weakening of the H‐bond network with T is crucial in decoupling the polarising glycine molecules from the other glycines and allowing the long‐range ferroelectric order to break down. A new parameterisation of the phase transition is demonstrated. Contrary to results of physical properties measurements, there is no evidence of a second low temperature phase transition in TGS – no low temperature anomalies were observed in the crystal structure.
Mountain pine beetle selectivity in old‐growth ponderosa pine forests, Montana, USA
Authors: Knapp Paul A. , Soulé Peter T. , Maxwell Justin T. 
Published: March 2013

AbstractA historically unprecedented mountain pine beetle (MPB) outbreak affected western Montana during the past decade. We examined radial growth rates (AD 1860–2007/8) of co‐occurring mature healthy and MPB‐infected ponderosa pine trees collected at two sites (Cabin Gulch and Kitchen Gulch) in western Montana and: (1) compared basal area increment (BAI) values within populations and between sites; (2) used carbon isotope analysis to calculate intrinsic water‐use efficiency (iWUE) at Cabin Gulch; and (3) compared climate‐growth responses using a suite of monthly climatic variables. BAI values within populations and between sites were similar until the last 20–30 years, at which point the visually healthy populations had consistently higher BAI values (22–34%) than the MPB‐infected trees. These results suggest that growth rates two–three decades prior to the current outbreak diverged between our selected populations, with the slower‐growing trees being more vulnerable to beetle infestation. Both samples from Cabin Gulch experienced upward trends in iWUE, with significant regime shifts toward higher iWUE beginning in 1955–59 for the visually healthy trees and 1960–64 for the MPB‐infected trees. Drought tolerance also varied between the two populations with the visually healthy trees having higher growth rates than MPB‐infected trees prior to infection during a multi‐decadal period of drying summertime conditions. Intrinsic water‐use efficiency significantly increased for both populations during the past 150 years, but there were no significant differences between the visually healthy and MPB‐infected chronologies.
Cationic and Neutral (Ar‐BIAN)Copper(I) Complexes Containing Phosphane and Arsane Ancillary Ligands: Synthesis, Molecular Structure and Catalytic Behaviour in Cycloaddition Reactions of Azides and Alkynes
Authors: Li Lidong , Lopes Patrícia S. , Figueira Cláudia A. , Gomes Clara S. B. , Duarte M. Teresa , Rosa Vitor , Fliedel Christophe , Avilés Teresa , Gomes Pedro T. 
Published: March 2013

AbstractInvited for the cover of this issue are the groups of Pedro T. Gomes (Universidade Técnica de Lisboa) and Teresa Avilés (Universidade Nova de Lisboa). The cover image shows the structure of one of the catalysts against a background of a bridge symbolising the collaboration between the two groups.
New highly robust divinyl benzene/acrylate polymer for immobilization of lipase CALB
Authors: Basso Alessandra , Froment Luc , Hesseler Martin , Serban Simona 
Published: March 2013

AbstractCandida antartica lipase B (CALB) is the most versatile biocatalyst and is, therefore, widely used in industry. Its advantages range from thermostability, stereoselectivity, and activity in organic solvents to the acceptance of nucleophiles other than water. The actual standard for industrial applications of CALB is the immobilized enzyme on Lewatit VP OC 1600 and is marketed under the name Novozym® 435. A new acrylic enzyme carrier (ECR1030) for the immobilization by adsorption of CALB and for use in batch or column reactors has been developed. The resin shows an activity of >9000 PLU/gDry, which is similar to Novozym® 435. Protein loading was 24.4 mg/gWet, and immobilizations yields higher than 90% were obtained. Unlike the resin used for the production of Novozym® 435, ECR1030 possesses high mechanical stability and is therefore more suitable for applications that expose the polymers to high mechanical stress, such as multiple reuses in stirred reactors.Practical applications: Immobilized CALB is the biocatalyst used in the widest amount of industrial applications due to its broad selectivity and stability. It can be used for the manufacture of specialty chemicals such as surfactants, amides, chiral amines, alcohols, biodiesel, and polyesters. Its industrial use is in stirred tanks or packed columns, so high mechanical stability is needed together with high activity and sustainable costs.
Formation and Rupture of a Supramolecular Nanocapsule Triggered on–off–on Supramolecular Switch for Zn2+
Authors: Jiang Song , Liu Man , Cui Yanting , Zou Dapeng , Wu Yangjie 
Published: March 2013

AbstractA novel selective fluorescence probe that contains 2‐p‐phenylimidazo[4,5‐f][1,10]phenanthroline and a viologen unit linked by a flexible chain was synthesized and found to be able to select zinc ions with a clear fluorescence enhancement and a large stokes shift in aqueous solution. This probe can also be designed as an on–off–on molecular switch by the formation and rupture of a supramolecular nanocapsule with cucurbit[8]uril (CB[8]) in aqueous solution.
Synthesis of β‐Lactam‐Tethered Polycyclic Fused Heterocycles through a Rearrangement by a One‐Pot Tandem [3+2] Cycloaddition Reaction
Authors: Rajesh Raju , Raghunathan Raghavachary 
Published: March 2013

AbstractWe have developed a one‐pot synthesis of polycyclic fused heterocyclic derivatives by the [3+2] cycloaddition of Baylis–Hillman adducts (BHA) derived from 4‐oxoazetidine‐2‐carbaldehydes as dipolarophiles. The BHA derived from methyl acrylate reacted with the azomethine ylides generated from sarcosine or proline, and the diketone isatin to give unexpected fused polycyclic pyrrolo/pyrrolizinoquinolinone derivatives. The products contain three rings (lactone, pyrrolidine, and lactam) fused at a single C–C junction. Similar reactions carried out with the BHA derived from acrylonitrile gave only the normal mono‐spiro cycloadducts as expected. The dipolarophiles reacted with azomethine ylides generated from other α‐diketones to give polycyclic fused furanopyrrolidine derivatives. The structures of the new heterocycles were confirmed by spectroscopic techniques and unambiguously proved by single‐crystal X‐ray analysis.