bluuebunny/crossref_metadata_2025_split huggingface dataset:
Preoperative early-stage lung cancer patients and local brain area changes: a cross-sectional observational descriptive study
Authors: Yuan Pei-Pei , Hua Xu-Yun 
Published: August 2024

IntroductionLung cancer is a major global health concern. Patients undergo a substantial process of emotional transformation following a lung cancer diagnosis, during which subtle changes in brain function and/or structure may occur. As such, the present study aimed to investigate the neuroplastic changes induced by negative emotions in patients with early-stage lung cancer.MethodsThis cross-sectional study recruited 35 patients with early-stage lung cancer and 33 age- and sex-matched healthy control patients. All participants completed the Hamilton Anxiety Rating Scale (HAMA), Hamilton Depression Rating Scale (HAMD), and functional magnetic resonance imaging (fMRI). Amplitude of low-frequency fluctuations (ALFF) and regional homogeneity (ReHo) were used as the fMRI indices. Correlations between the clinical assessments and ALFF and ReHo values were calculated.ResultsOur analysis revealed no significant differences in HAMD and HAMA scores between patients and control patients (p &gt; 0.05). However, significant alterations in ALFF and ReHo were observed in multiple brain regions in patients with early-stage lung cancer compared to healthy controls (PFalseDiscoveryRate &lt; 0.05). Specifically, ALFF values were decreased in the right postcentral gyrus, calcarine, and left middle cingulate, while ReHo values increased in the right angular gyrus and decreased in the bilateral postcentral gyrus, insula, left calcarine, putamen, superior temporal gyrus, middle cingulate, and right Rolandic gyrus. The HAMD score was significantly correlated with the ALFF value in the right postcentral gyrus (P = 0.007).ConclusionThis study provides valuable insights into the adaptive responses of the brain following the early diagnosis of lung cancer, revealing potential disturbances in negative emotional processing. Harnessing neuroplasticity may open new avenues for the establishment of personalized treatment strategies and targeted interventions to support the emotional and mental health of patients with lung cancer.
Dynamic analysis of the relationship between systemic lupus erythematosus disease activity and psychosocial support
Authors: Lu Miao , Liu Min , Zhan Kuijun , Chen Yutong , Liu Xide 
Published: August 2024

BackgroundSystemic lupus erythematosus (SLE) is a multi-system autoimmune disease that significantly affects both the physical and mental health of patients. Psychosocial support systems play a crucial role in managing chronic diseases, yet their specific impact on the disease activity of SLE patients remains unclear. This study aims to explore the dynamic relationship between disease activity in SLE patients and various types of psychosocial support systems.MethodsWe conducted a retrospective longitudinal observational study, including 150 SLE patients who received treatment at our hospital from January 2022 to January 2023. Emotional support, tangible support, social interaction support, and informational support were assessed using the revised Social Support Rating Scale. Disease activity was quantified using the European Consensus Lupus Activity Measurement. The relationship between psychosocial support and disease activity was analyzed using Spearman’s rank correlation coefficient and multiple linear regression models, with Bootstrap resampling employed to test the robustness of the results.ResultsWe found a significant negative correlation between psychosocial support and SLE disease activity, with emotional support, social interaction support, and informational support showing stronger negative correlations. Multiple regression analysis revealed that the inhibitory effects of emotional support, social interaction support, and informational support on disease activity increased over time. Although the impact of tangible support was not statistically significant, it gradually became more apparent over time.ConclusionOur findings indicate a significant negative correlation between psychosocial support and SLE disease activity, particularly with emotional support, social interaction support, and informational support. Over time, the impact of tangible support also becomes evident. These findings provide important references for the comprehensive treatment and management of SLE patients. However, due to the observational nature of the study, the causality of this relationship requires further exploration.
The relationship between adolescents’ physical activity, circadian rhythms, and sleep
Authors: Liu Daoli , He Jin , Li Hengfen 
Published: August 2024

ObjectiveTo explore the correlation between physical activity, circadian rhythms, and sleep in adolescents, and analyze the influencing factors of sleep quality in this population.MethodsA total of 381 high school students were selected through cluster sampling in a specific high school. The Pittsburgh Sleep Quality Index (PSQI) was employed to categorize the participants into a good sleep quality group (n=199) and a poor sleep quality group (n=182). Comprehensive assessments were conducted using the Hamilton Depression Rating Scale (HAMD), Hamilton Anxiety Rating Scale (HAMA), PSQI, Morningness-Eveningness Questionnaire-5 (MEQ-5), and International Physical Activity Questionnaire Short Form (IPAQ-SF).ResultsThe prevalence of poor sleep quality is 47.8%. The BMI in the poor sleep quality group is higher than that in the good sleep quality group, and the male ratio is lower than that in the good sleep quality group. The poor sleep quality group exhibits significantly higher levels of depression, anxiety, evening chronotype, and low physical activity compared to the good sleep quality group.Spearman rank correlation analysis revealed a positive correlation between the PSQI total score and HAMA and HAMD scores, and a negative correlation with physical activity and MEQ-5 scores. Binary logistic stepwise regression analysis identified lack of physical activity, eveningness chronotype, anxiety, and depression as risk factors for poor sleep quality.ConclusionAdolescent sleep quality is correlated with gender, BMI, anxiety, depression, chronotype, and physical activity levels. The findings highlight the importance of considering these factors in interventions aimed at improving sleep health in adolescents.
The impact of parental migration patterns, timing, and duration on the health of rural Chinese children
Authors: Wang Feng , Wang Ying , Liu Shumei , Cui Linlin , Li Feimeng , Wang Xiaohe 
Published: August 2024

BackgroundParent–child separation raises concerns for the well-being of 69 million left-behind children (LBC) in China. However, the effects of parental migration status, timing of migration, and migration duration on the health of children remain unclear. This study aims to explore the association between different parent–child separation experience and a range of health outcomes in rural Chinese children.MethodA sample of 2,355 students, grades 5 to 8, from two provinces in China were recruited. Standardized self-report instruments collected data on demographics, separation status, and children’s health conditions.ResultsFull data were available for 274 children with both parents currently migrating (BLBC), 638 children with one parent currently migrating (SLBC), 658 children with parents previously migrated (PLBC) and 785 children with non-migrating parents (NLBC). Regression model results showed that, compared to the NLBC group, BLBC and PLBC exhibited lower self-rated health (p &lt; 0.05), higher depression (p &lt; 0.05), and higher rates of non-suicidal self-injury behaviors (p &lt; 0.05) and suicidal ideation (p &lt; 0.05). Children who experienced parental separation before the age of three were at a higher risk for four health indicators. Additionally, children left behind by parents for more than 7 years had significantly worse health outcomes.ConclusionChildren who have experienced both current and previous parental migration, as well as earlier parental migration age and longer migration duration, are at a disadvantage in terms of health. These findings highlight the need for targeted interventions focusing on the most vulnerable children.
Transitioning towards sustainable agriculture: analysing the factors and impact of adopting multiple sustainable inputs by paddy farmers in India
Authors: Jha Girish Kumar , Velayudhan Praveen Koovalamkadu , Bhatia Arti , Laishram Chinglembi , Kumar Deepak , Begho Toritseju , Eory Vera 
Published: August 2024

IntroductionThere is a global priority to ensure food security, environmental conservation and sustainability. The adoption of inputs such as organic manures, biofertilisers, and biopesticides has been widely promoted as a way to enhance agricultural sustainability, yet their adoption rates remain notably low. The study examines the determinants and impact of the adoption of multiple sustainable inputs by paddy farmers in India. The study also examines the drivers behind the intensity of their adoption and their technical efficiency.MethodsThe study utilises the survey dataset on paddy farmers from “Situation Assessment of Agricultural Households and Land and Livestock Holdings of Households in Rural India” of the 77th National Sample Survey (NSSO) round. The reference period for data collection was the agricultural year from July 2018 to June 2019. The analytical methods employed include the Multivariate Probit and Ordered Probit models, Seemingly Unrelated Regression, Regression Adjustment model, and Stochastic Frontier method.ResultsThe empirical findings reveal that the adoption and intensity of sustainable inputs depend significantly on factors such as the household head’s age and education, household size, and access to extension services. Adopting sustainable inputs has significant benefits, such as increased harvest value. However, the currently available technical advisory services are limited in effectively promoting the expenditure on sustainable inputs. Technical efficiency analysis underscores the potential for improvement and the importance of utilising optimal input levels. The research findings provide strong evidence in favour of advocating for the use of sustainable inputs in paddy farming.
Predictive value of tip-apex distance and calcar-referenced tip-apex distance for cut-out in 398 femoral intertrochanteric fractures treated in a private practice with dynamic intramedullary nailing
Authors: Barra Amariel E. , Barrios Carlos 
Published: August 2024

IntroductionCut-out, a biomechanical complication, is one of the most common causes of internal fixation failure of trochanteric hip fractures. The tip-apex distance (TAD) and the calcar-referenced tip-apex distance (CalTAD) have been suggested as the radiographic parameters that most predict the risk of cut-out. The purpose of this study was to check whether these two factors could predict implant cut-out in a series 398 of intertrochanteric hip fractures, treated by dynamic intramedullary nailing with the Trigen Intertan short nail.MethodsWe reviewed 398 consecutive intertrochanteric fractures included in a prospective study and treated in a single private hospital by the same surgeon. The radiographic parameters were obtained from anteroposterior (AP) and axial hip plain radiographs before surgery, immediately postoperatively, and every 3 weeks after surgery until 3 months postoperatively, and every month until the 6-month follow-up. The concept of medial cortex support (MCS) was also analyzed as a criterion for evaluating the quality of fracture reduction.ResultsThe overall cut-out rate was 2.3% (9/398). The significant parameters in the univariate analysis were AO fracture type, quality of fracture reduction (p = 0.02), TAD (p &lt; 0.001), CalTAD (p = 0.001), and quality of reduction. No statistically significant relationships were observed between the occurrence of cut-out and sex, age, fracture side, and American Society of Anesthesiologists type. Varus collapse and cut-out were only found in cases of negative MCS (22.2% and 77.8%, respectively). Multivariate analysis showed that only TAD showed an independent significant relationship to cut-out (p &lt; 0.001). In this study, CalTAD has no predictive value in the multivariable analysis.ConclusionsOur findings differed from those in previous reported studies suggesting that CalTAD is the best predictor of cut-out. According to our data, careful optimal reduction ensuring stable fixation with TAD &gt;25 mm reduced the occurrence of cut-out after dynamic intramedullary nailing of intertrochanteric fractures.
Measuring the effect of the anti-nerve growth factor antibodies bedinvetmab and frunevetmab on quality of life in dogs and cats with osteoarthritis using a validated health-related quality of life outcome measure: an observational real-world study
Authors: Reid Jacqueline , Gildea Edwina , Davies Vinny , Thompson Jill , Scott Marian 
Published: August 2024

BackgroundOsteoarthritis causes chronic pain, impaired joint function, decreased mobility and negatively impacts quality of life (QOL). Anti-nerve growth factor antibodies bedinvetmab for dogs and frunevetmab for cats are licensed for the alleviation of osteoarthritis pain but their QOL impact is unreported. Our aim was to determine if these therapeutics improve QOL using a validated health-related QOL measure that generates scores in four domains of QOL-energetic and enthusiastic (E/E), happy and content (H/C), active and comfortable (A/C) and calm and relaxed (C/R)-in the dog and three in the cat-vitality, comfort and emotional wellbeing (EWB). Summary scores for physical wellbeing (PWB) and emotional wellbeing (EWB) for dogs and PWB for cats are calculated from the domain scores.MethodsAnimals received bedinvetmab (dogs) at 0.5–1 mg/kg or frunevetmab (cats) at 1–2.8 mg/kg by subcutaneous injection on days 0, 28 and 56 and owners completed QOL assessments within 48 hours of day 0 and on days 14, 28, 56, 63 and 70 using a study-specific app.ResultsAssessments were completed by 75 dog and 56 cat owners. By day 14 there was a statistically significant improvement (p ≤ 0.001) in PWB, EWB and all domains except C/R (p = 0.005) in dogs and in all domains and PWB in the cat. Subsequently there was a continued improvement in all domains and summary scores (p ≤ 0.001) except for H/C in the dog and EWB in the cat, which were excluded from the statistical model. The overall improvement in all domain scores in the cat and E/E and A/C in the dog exceeded the previously reported minimum important difference scores for the QOL measure, indicating a clinically significant change.ConclusionTreatment with bedinvetmab and frunevetmab produced a significant improvement in the QOL of dogs and cats. This latest evidence for the use of these OA pain medications could be helpful in the clinical management of osteoarthritis and post-marketing clinical trials.
Zeptosecond-Yoctosecond Pulses Generated by Nonlinear Inverse Thomson Scattering: Modulation and Spatiotemporal Properties
Authors: Zhang Yi , Yang Qingyu , Wang Jihong , Gong Xiaotian , Tian Youwei 
Published: August 2024

Ultrashort light pulses have strong research and application values, while nonlinear inverse Thomson scattering has been considered as a unique source of zepto-yoctosecond pulses. Here, the mechanism of nonlinear inverse Thomson scattering of a high-energy electron colliding with a tightly focused intense laser pulse is investigated through numerical simulation. The time-compression effect was proposed to explain the origin of ultrashort pulses and the nonlinear phenomenon of electron radiation in the time–space joint distribution. It is found that the time scale of electron radiation is orders of magnitude shorter than that of electron motion, and the increases in laser intensity and electron initial energy will result in stronger and shorter pulses. Yoctosecond pulses can be generated by a laser pulse with an intensity of 1.384×1020 W/cm2 and an electron with an initial energy of 51.1 MeV. These results provide theoretical and numerical basis for generating shorter light pulses.
Existence of the Nontrivial Solution for a p-Kirchhoff Problem with Critical Growth and Logarithmic Nonlinearity
Authors: Cai Lixiang , Miao Qing 
Published: August 2024

In this paper, we mainly study the p-Kirchhoff type equations with logarithmic nonlinear terms and critical growth: −M∫Ω∇updxΔpu=up∗−2u+λup−2u−up−2ulnu2     x∈Ω, u=0 x∈∂Ω,                  where Ω⊂ℝN is a bounded domain with a smooth boundary, 2<p<p∗<N, and both p and N are positive integers. By using the Nehari manifold and the Mountain Pass Theorem without the Palais-Smale compactness condition, it was proved that the equation had at least one nontrivial solution under appropriate conditions. It addresses the challenges posed by the critical term, the Kirchhoff nonlocal term and the logarithmic nonlinear term. Additionally, it extends partial results of the Brézis–Nirenberg problem with logarithmic perturbation from p = 2 to more general p-Kirchhoff type problems.
Can Functional Micro-organisms Associated with Pumpkin Sizes Be Sought Out from the Soil?—A Comparison of Soil Microbial Community Structures in Rhizospheres between Giant- and Small-Sized Pumpkin Varieties
Authors: Zhu Yu , Zhou Xinyan , Li Jiaoming , Feng Junqian , Huang Ziyue , Chen Baoling , Liu Wenjun , Yang Shangdong 
Published: August 2024

To elucidate the biological mechanisms driving the growth of various pumpkin varieties to different sizes under identical management conditions while in the same field, the soil microbial community structures in the rhizospheres of giant-pumpkin (GP) and small-pumpkin (SP) varieties were analyzed. The results revealed that a significantly higher abundance of bacterial communities could be detected in the rhizospheres of the giant pumpkin varieties, such as Gemmatimonadota, norank__f__norank__o_Gaiellales, norank__f__Gemmatimonadaceae, Bryobacter, Sphingomonas, norank__f__JG30-KF-AS9, and norank__f__norank__o___Elsterales, than in those of the small-sized pumpkins. Additionally, norank_f__norank_o__Elsterale, Ellin6067, norank_f__67-14, and Chujaibacter were unique dominant soil bacteria genera in the rhizospheres of the giant pumpkins. By contrast, Arthrobacter, norank_f__Roseiflexaceae, unclassified_f__Rhizobiaceae, Allorhizobium-Neorhizobium-Pararhizobium-Rhizobium, Nocardioides, Mycobacterium, norank_f__norank_o__Vicinamibacterales, and Burkholderia-Caballeronia-Paraburkholderia were the unique dominant soil bacterial genera in the rhizospheres of the small pumpkins. Moreover, at the fungal genus level, unclassified_c__Chytridiomycetes, Podosphaera, and Colletotrichum presented significant differences between the giant-pumpkin (GP) and small-pumpkin (SP) rhizospheres. In addition, unclassified__p__Rozellomycota, unclassified__c__Chytridiomycetes, Penicillium, and unclassified__f__Chaetomiaceae were unique dominant soil fungal genera in the rhizospheres of the giant pumpkins (GPs). By contrast, Podosphaera, Colletotrichum, unclassified__f__Plectosphaerellaceae, unclassified__o_Boletales, Scytalidium, unclassified__p__Rozellomycota, and unclassified__o_Agaricales were the unique dominant soil fungal genera in the rhizospheres of the small pumpkins (SPs). PICRUSt and FUNGuild functional prediction analyses revealed that the giant-pumpkin rhizosphere microbial community had significantly increased translation, ribosomal structure and biogenesis, nucleotide transport and metabolism, defense mechanisms, replication, recombination and repair, wood saprotroph, and undefined saprotroph levels. The above results suggest that the soil microbial compositions differed between the rhizospheres of the giant- (GP) and small-pumpkin (SP) varieties, even though the plants were grown in the same field under identical management conditions. Meanwhile, bacterial genera such as norank_f__norank_o__Elsterale, Ellin6067, norank_f__67-14, and Chujaibacter, in addition to fungal genera such as unclassified__p__Rozellomycota, unclassified__c__Chytridiomycetes, Penicillium, and unclassified__f__Chaetomiaceae, can be speculated as potential soil functional micro-organisms associated with improved pumpkin size.
Relationship Between Mothers Level of Knowledge About Stunting Prevention and the Nutritional Status of Toddler
Authors: Wahyuningsih Melania , Liliana Anita 
Published: August 2024

Abstract Stunting is a serious problem if not addressed, causing the quality of human resources to decline. Stunting prevention is influenced by the mother's level of knowledge about stunting. To find out the nutritional status of toddlers, it is necessary to measure the nutritional status of toddlers every month at the Posyandu. This research is descriptive correlation to determine the relationship between the level of maternal knowledge about preventing stuting and the nutritional status of toddlers. The sample in this study was 39 mothers who had toddlers and whose toddlers were weighed at Posyandu Wijaya Kusuma Nyamplung Lor Balecatur Gamping Sleman. The mother's level of knowledge about stunting was measured using a questionnaire distributed after the mother weighed her toddler. The results of the study showed that the majority of mothers had secondary education, had a good level of stunting prevention, the nutritional status of the toddlers was mostly good and there was a significant relationship between the mother's level of knowledge of stunting prevention and the nutritional status of the toddlers, p value <0.05 Key wards: Stunting, nutritional status
Effectiveness of Accupressure on Post Operative Nausea and Vomiting in Post Abdominal Surgery Patients A Systematic Review
Authors: HS SH Septyanti , Dahlia Debie 
Published: August 2024

Surgery is a form of medical therapy that can cause stress because it poses a threat to a person's body, integrity and soul (Mazzotta et al., 2020). The surgical process is also often associated with high treatment costs, infectious complications, perioperative nausea and vomiting (PONV), and readmissions (Carmichael et al., 2017). An integrated and continuous nursing care process can make a difference between a negative or positive surgical experience and can influence the client's recovery process (Abeles et al., 2017). Complementary therapy is known as traditional therapy combined in modern medicine. Complementary is the use of traditional therapy into modern medicine (Tóth et al., 2018). Some have been scientifically proven, for example, touch therapy to increase relaxation, reduce pain, reduce anxiety, speed up wound healing, and make a positive contribution to psychoimmunological changes (Niu et al., 2021). So it is necessary to carry out a systematic review of complementary therapies, especially acupressure, which is used to treat complaints of nausea and vomiting in post-abdominal surgery patients to identify the effectiveness of acupressure therapy for post-operative nausea and vomiting in post-abdominal surgery patients. The research design that will be carried out is a systematic review using the PRISMA flow diagram. Researchers used PIO and searched for articles that were in English and published from 2013 to November 2023. The databases used were Proquest, Pubmed, Sage, Clinical Key Nursing, Science Direct and Google Scholar. Researchers use the Covidence tool to carry out the data selection process through to extraction and use the CASP instrument to evaluate research articles. Eight articles were identified and analyzed. Five articles used an RCT design, one article used a Prospective Cohort design, and one article used a semi-experimental design. The sample size of the reported studies ranged from 60 to 227 people conducted in various geographic regions such as Turkey, Iran and China. Acupressure therapy used at several points has been proven to help reduce PONV in post-abdominal surgery patients. Acupressure therapy can reduce PONV complaints in post-abdominal surgery patients.