bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sistem Klasifikasi Jenis Kain Berdasarkan Tekstur Menggunakan Metode Support Vector Machine Berbasis Web Flask
Authors: Anis Yusrotun Nadhiroh  
Published: August 2024

Kain adalah salah satu dari ribuan hasil karya manusia di penjuru dunia. Kain sendiri terbuat dari tenunan benang yang berasal dari bahan kapas, sutra, dan sintesis lainnya. Pada umumnya kain adalah salah satu bahan dasar untuk membuat pakaian, tetapi kain juga bisa digunakan untuk bahan dasar jilbab, tas, celana, selimut dan kebutuhan lainnya. Sampai saat ini berbagai macam jenis kain dan teksturnya yang di pengaruhi trend model fashion. Pengenalan tekstur kain biasanya dilakukan dengan metode manual oleh mata, dengan perabaan, maupun diasumsikan secara pribadi. Untuk keperluan yang lebih luas misalnya toko online, maka klasifikasi kain secara manual tidak bisa dilakukan. Tujuan dari penelitian ini yaitu mendesain, mengimplementasikan, dan mengoptimalkan model Support Vector Machine (SVM) untuk mencapai tingkat akurasi klasifikasi yang tinggi. dengan melibatkan pemilihan parameter SVM yang optimal untuk menemukan yang paling sesuai dengan data tekstur kain.Adapun metode yang digunakan dalam penelitian ini metode Support Vector Machine berbasis Web Flask, dimana fokus pada citra tekstil klasifikasi berdasarkan teksturnya yang diimplementasikan adalah Gray Level Co- occurrencee Matrix (GLCM). Hasil dari penelitian ini menggunakan dataset dengan 4 jenis kain masing-masing 150 gambar sehingga total dataset 600 gambar. Pada tahap pree-processing mengubah warna gambar asli ke grayscale (keabuan) dan mengubah gambar dalam ukuran yang sama yaitu 450x450. Kemudian hasil dari ekstraksi fitur GLCM dilakukan proses pengklasifikasian menggunakan metode Support Vector Machine (SVM) dengan menggunakan 480 data training dan 120 data testing diperoleh nilai akurasi 47%. Dan prediksi jenis kain diimplementasikan ke Web Flask, sehingga Web Flask dapat memprediksi jenis kain.
IMPACTO DA UTILIZAÇÃO DO AZEITE DE OLIVA EXTRAVIRGEM E DO AZEITE DE ABACATE EXTRA VIRGEM NO PROCESSO DE EMAGRECIMENTO.
Authors: Ribeiro Dias Kamilla , Miranda Alves Jéssica Mariana , Castro Pereira Paixão Mirian Patrícia 
Published: August 2024

A obesidade trata-se de uma doença crônica, que pode causar problemas cardiovasculares, tornando-se um problema de saúde pública. Com isso, a busca por intervenções dietéticas que auxiliam no processo do emagrecimento é de grande relevância. Dito isso, o objetivo deste estudo consistiu em avaliar o impacto da utilização do azeite de oliva extra virgem e do azeite de abacate extra virgem no emagrecimento em praticantes de atividade física. Trata-se de um ensaio clínico randomizado, experimental, duplo-cego, controlado por placebo, realizado em academias e na clínica do Centro Universitário de Vitória, Espírito Santo e que apresenta uma amostra de 45 indivíduos, com idade entre 20 a 59 anos. O estado nutricional foi analisado por meio da avaliação dos dados antropométricos e do consumo alimentar. A fim de avaliar a adequação de ingestão de nutrientes e energia utilizou-se a ingestão dietética recomendada, havendo também a elaboração de planos alimentares individualizados, orientação e intervenção nutricional. No que concerne aos aspectos éticos, somente participaram da pesquisa os pacientes que assinaram o termo de compromisso livre e esclarecido, com o referido projeto enviando ao comitê de ética do Centro Universitário Salesiano (CAAE: 65749222.0.0000.5068). Os dados quantitativos foram descritos em média, desvio padrão, mediana, máximo e mínimo e as variáveis qualitativas descritas a partir de frequência absoluta e relativa. Espera-se que a partir deste estudo seja possível identificar um impacto na utilização do azeite extra virgem de abacate e oliva na saúde e na redução do tecido adiposo dos participantes.
Review of Cost Control Research in Prefabricated Construction under EPC Mode
Authors: Weihao Huang 
Published: August 2024

Aims: Amidst the accelerating global urbanization and growing demand for sustainable development, prefabricated construction emerges as a pivotal transformational force in the construction industry due to its efficiency and environmental friendliness. This paper comprehensively reviews cost control research in prefabricated construction under the EPC (Engineering, Procurement, Construction) model.
Study Design: The study adopts a literature-based approach, incorporating findings from domestic and international scholars, to uncover the critical issues and challenges in cost control within the EPC framework. Additionally, it analyzes the application of technological innovations such as BIM (Building Information Modeling) and DEMATEL (Decision Making Trial and Evaluation Laboratory) in cost control, offering a theoretical foundation and practical guidance for prefabricated construction under EPC.
Place and Duration of Study: The research spans various regions globally, examining recent practices and theoretical advancements in cost control for prefabricated construction projects under EPC over the past decade to ensure timeliness and comprehensiveness.
Methodology: The methodology encompasses a systematic literature review to construct a theoretical framework, coupled with an analysis of case studies showcasing effective cost control measures. Furthermore, the study explores the utilization of BIM and DEMATEL to enhance cost prediction accuracy, process monitoring, and decision-making support.
Results: The findings reveal that the EPC model facilitates more systematic and efficient cost control in prefabricated construction. The application of BIM significantly improves cost forecasting precision and process transparency, enabling timely cost deviation identification and correction. DEMATEL effectively identifies key cost drivers and their interrelationships, informing targeted cost control strategies.
Conclusion: This paper underscores the significance of cost control in prefabricated construction under the EPC model and highlights the pivotal role of BIM and DEMATEL in enhancing cost control effectiveness. It concludes by advocating for deeper integration of prefabricated construction with the EPC model to propel the green, intelligent transformation and sustainable development of the construction industry.
Progressive Multifocal Leukoencephalitis of the Immunocompromised Subject: A Case Report from Zinder National Hospital
Authors: Mahamadou Doutchi , Fils Souleymane Adoum , Moustapha Lamine Mahaman , Abdoul-Aziz Adamou Bara , Hamsatou Bagnou , Aziz Garba Abdoul , Eric Adehossi 
Published: August 2024

Progressive multifocal leukoencephalitis (PML) is a rare opportunistic infection of HIV-infected individuals. It is a viral infection caused by the John Cunningham (JC) virus, which occurs during the AIDS stage. An elderly patient immunosuppressed by HIV for more than 5 years presented to the HNZ SMIT with headache, vomiting, visual disturbances, speech disorders and numbness of the limbs, all of which had been evolving in a febrile context for more than seven months. Neurological examination revealed left hemiparesis, frontal syndrome, temporal syndrome and homolateral hemianopia. Cerebral computed tomography revealed multiple lesions of leukoencephalitis. PCR revealed JC virus. The patient was put on corticosteroids, rehydration and nursing care. The course was marked by a progressive deterioration in the patient's neurological condition, culminating in death. We report the clinical, biological and CT features of this progressive multifocal leukoencephalitis.
Synthesis of Branched DNA Using Oxidatively Cleavable Tritylsulfenyl as a Hydroxy Protecting Group
Authors: Seio Kohji , Kanamori Takashi , Sekine Mitsuo 
Published: September 2014

AbstractThe application of oxidatively cleavable tritylsulfenyl (TrS) group to the synthesis of branched DNA is described. The TrS protecting group can be removed by treatment with 1 M aqueous iodine, while it is stable toward an oxaziridine‐type oxidant. At the same time, the sulfur‐oxygen linkage showed sufficient stability under the acidic and basic conditions used in oligonucleotide synthesis. These properties of the TrS group enabled the synthesis of branched DNA using a branched phosphoramidite in which the two hydroxy groups are protected by a 4,4′‐dimethoxytrityl (DMTr) group or a TrS group. In this unit, we describe an example of the synthesis of a three‐way branched DNA using a branched phosphoramidite. Curr. Protoc. Nucleic Acid Chem. 58:2.18.1‐2.18.19. © 2014 by John Wiley & Sons, Inc.
Using Triple‐Helix‐Forming Peptide Nucleic Acids for Sequence‐Selective Recognition of Double‐Stranded RNA
Authors: Hnedzko Dziyana , Cheruiyot Samwel K. , Rozners Eriks 
Published: September 2014

AbstractNon‐coding RNAs play important roles in regulation of gene expression. Specific recognition and inhibition of these biologically important RNAs that form complex double‐helical structures will be highly useful for fundamental studies in biology and practical applications in medicine. This protocol describes a strategy developed in our laboratory for sequence‐selective recognition of double‐stranded RNA (dsRNA) using triple‐helix‐forming peptide nucleic acids (PNAs) that bind in the major grove of the RNA helix. The strategy developed uses chemically modified nucleobases, such as 2‐aminopyridine (M), which enables strong triple‐helical binding under physiologically relevant conditions, and 2‐pyrimidinone (P) and 3‐oxo‐2,3‐dihydropyridazine (E), which enable recognition of isolated pyrimidines in the purine‐rich strand of the RNA duplex. Detailed protocols for preparation of modified PNA monomers, solid‐phase synthesis, HPLC purification of PNA oligomers, and measuring dsRNA binding affinity using isothermal titration calorimetry are included. Curr. Protoc. Nucleic Acid Chem. 58:4.60.1‐4.60.23. © 2014 by John Wiley & Sons, Inc.
MalaCards: A Comprehensive Automatically‐Mined Database of Human Diseases
Authors: Rappaport Noa , Twik Michal , Nativ Noam , Stelzer Gil , Bahir Iris , Stein Tsippi Iny , Safran Marilyn , Lancet Doron 
Published: September 2014

AbstractSystems medicine provides insights into mechanisms of human diseases, and expedites the development of better diagnostics and drugs. To facilitate such strategies, we initiated MalaCards, a compendium of human diseases and their annotations, integrating and often remodeling information from 64 data sources. MalaCards employs, among others, the proven automatic data‐mining strategies established in the construction of GeneCards, our widely used compendium of human genes. The development of MalaCards poses many algorithmic challenges, such as disease name unification, integrated classification, gene‐disease association, and disease‐targeted expression analysis. MalaCards displays a Web card for each of >19,000 human diseases, with 17 sections, including textual summaries, related diseases, related genes, genetic variations and tests, and relevant publications. Also included are a powerful search engine and a variety of categorized disease lists. This unit describes two basic protocols to search and browse MalaCards effectively. Curr. Protoc. Bioinform. 47:1.24.1‐1.24.19. © 2014 by John Wiley & Sons, Inc.
Using Weeder, Pscan, and PscanChIP for the Discovery of Enriched Transcription Factor Binding Site Motifs in Nucleotide Sequences
Authors: Zambelli Federico , Pesole Graziano , Pavesi Giulio 
Published: September 2014

AbstractOne of the greatest challenges facing modern molecular biology is understanding the complex mechanisms regulating gene expression. A fundamental step in this process requires the characterization of sequence motifs involved in the regulation of gene expression at transcriptional and post‐transcriptional levels. In particular, transcription is modulated by the interaction of transcription factors (TFs) with their corresponding binding sites. Weeder, Pscan, and PscanChIP are software tools freely available for noncommercial users as a stand‐alone or Web‐based applications for the automatic discovery of conserved motifs in a set of DNA sequences likely to be bound by the same TFs. Input for the tools can be promoter sequences from co‐expressed or co‐regulated genes (for which Weeder and Pscan are suitable), or regions identified through genome wide ChIP‐seq or similar experiments (Weeder and PscanChIP). The motifs are either found by a de novo approach (Weeder) or by using descriptors of the binding specificity of TFs (Pscan and PscanChIP). Curr. Protoc. Bioinform. 47:2.11.1‐2.11.31. © 2014 by John Wiley & Sons, Inc.
Biological Network Exploration with Cytoscape 3
Authors: Su Gang , Morris John H. , Demchak Barry , Bader Gary D. 
Published: September 2014

AbstractCytoscape is one of the most popular open‐source software tools for the visual exploration of biomedical networks composed of protein, gene, and other types of interactions. It offers researchers a versatile and interactive visualization interface for exploring complex biological interconnections supported by diverse annotation and experimental data, thereby facilitating research tasks such as predicting gene function and constructing pathways. Cytoscape provides core functionality to load, visualize, search, filter, and save networks, and hundreds of Apps extend this functionality to address specific research needs. The latest generation of Cytoscape (version 3.0 and later) has substantial improvements in function, user interface, and performance relative to previous versions. This protocol aims to jump‐start new users with specific protocols for basic Cytoscape functions, such as installing Cytoscape and Cytoscape Apps, loading data, visualizing and navigating the networks, visualizing network associated data (attributes), and identifying clusters. It also highlights new features that benefit experienced users. Curr. Protoc. Bioinform. 47:8.13.1‐8.13.24. © 2014 by John Wiley & Sons, Inc.
Hybrid modeling and receding horizon control of sewer networks
Authors: Joseph‐Duran Bernat , Ocampo‐Martinez Carlos , Cembrano Gabriela 
Published: September 2014

AbstractIn this work, a control‐oriented sewer network model is presented based on a hybrid linear modeling framework. The model equations are described independently for each network element, thus allowing the model to be applied to a broad class of networks. A parameter calibration procedure using data obtained from simulation software that solves the physically based model equations is described and validation results are given for a case study. Using the control model equations, an optimal control problem to minimize flooding and pollution is formulated to be solved by means of mixed‐integer linear or quadratic programming. A receding horizon control strategy based on this optimal control problem is applied to the case study using the simulation software as a virtual reality. Results of this closed‐loop simulation tests show the effectiveness of the proposed approach in fulfilling the control objectives while complying with physical and operational constraints.
Processes controlling water vapor in the upper troposphere/lowermost stratosphere: An analysis of 8 years of monthly measurements by the IAGOS‐CARIBIC observatory
Authors: Zahn A. , Christner E. , van Velthoven P. F. J. , Rauthe‐Schöch A. , Brenninkmeijer C. A. M. 
Published: September 2014

AbstractAn extensive set of in situ water vapor (H2O) data obtained by the IAGOS‐CARIBIC passenger aircraft at 10–12 km altitude over 8 years (2005–2013) is analyzed. A multifaceted description of the vertical distribution of H2O from the upper troposphere (UT) via the extratropical tropopause mixing layer (exTL) into the lowermost stratosphere (LMS) is given. Compared to longer‐lived trace gases, H2O is highly variable in the UT and exTL. It undergoes considerable seasonal variation, with maxima in summer and in phase from the UT up to ~4 km above the tropopause. The transport and dehydration pathways of air starting at the Earth's surface and ending at 10–12 km altitude are reconstructed based upon (i) potential temperature (θ), (ii) relative humidity with respect to ice (RHi), and (iii) back trajectories as a function of altitude relative to the tropopause. RHi of an air mass was found to be primarily determined by its temperature change during recent vertical movement, i.e., cooling during ascent/expansion and warming during descent/compression. The data show, with great clarity, that H2O and RHi at 10–12 km altitude are controlled by three dominant transport/dehydration pathways: (i) the Hadley circulation, i.e., convective uplift in the tropics and poleward directed subsidence drying from the tropical tropopause layer with observed RHi down to 2%; (ii) warm conveyor belts and midlatitude convection transporting moist air into the UT with observed RHi usually above 60%; and (iii) the Brewer–Dobson shallow and deep branches with observed RHi down to 1%.
Glycomic Analysis of Glycans Released from Glycoproteins Using Chemical Immobilization and Mass Spectrometry
Authors: Yang Shuang , Zhang Hui 
Published: September 2014

AbstractProtein glycosylation is one of most common protein modifications and is involved in many biological activities. N‐linked and O‐linked glycosylation not only represent abundant glycan modifications, but also are structurally diverse. Mass spectrometry has emerged as a major method for glycomic analysis. However, glycan extraction from proteins and glycan modification are two critical steps in glycomic analysis of glycans using mass spectrometry. In this protocol, we describe a novel and high‐throughput method for isolation and modification of glycans from glycoproteins using a chemoenzymatic approach on solid‐phase. Proteins are first immobilized to a solid support and unconjugated molecules are washed away; glycans, while still linked to glycoproteins on the solid support, can be treated enzymatically or chemically on solid phase for glycan derivatization. Glycans are then released from the solid support for analysis by mass spectrometry. The procedures outlined are robust and useful for high‐throughput glycomic analysis from complex biological or clinical samples. Curr. Protoc. Chem. Biol. 6:191‐208 © 2014 by John Wiley & Sons, Inc.
Supramolekulare Chemie von Anionen: von der Erkennung zur chemischen Anwendung
Authors: Evans Nicholas H. , Beer Paul D. 
Published: September 2014

AbstractSeit der Jahrtausendwende fanden bemerkenswerte Fortschritte bei der Bindung und dem Nachweis von Anionen statt, die teilweise von den Erkenntnissen zur Ausnutzung von Wasserstoffbrücken ebenso wie den zuvor selten eingesetzten Anionen‐π‐Wechselwirkungen und Halogenbrücken angetrieben wurden. Die supramolekulare Chemie von Anionen wurde indes substantiell über die Anionenerkennung hinaus weiterentwickelt und umfasst nun verschiedene Disziplinen. Große Fortschritte wurden bei der Synthese von Makrocyclen und ineinandergreifenden molekularen Architekturen mit Anionen als Templaten erzielt, während die Untersuchung von anionischen Transmembrantransportern aus dem Nichts heraus zu einem rasch wachsenden Forschungsgebiet erblühte. Die supramolekulare Chemie der Anionen kam außerdem in verschiedenen Anwendungsbereichen wie der Katalyse, der Ionenextraktion und der Verwendung von Anionen als Impuls für molekulare Systeme zum praktischen Einsatz.
Reprogramming Nonribosomal Peptide Synthetases for “Clickable” Amino Acids
Authors: Kries Hajo , Wachtel Rudolf , Pabst Anja , Wanner Benedikt , Niquille David , Hilvert Donald 
Published: September 2014

AbstractNonribosomal peptide synthetases (NRPSs) are multifunctional enzymes that produce a wide array of bioactive peptides. Here we show that a single tryptophan‐to‐serine mutation in phenylalanine‐specific NRPS adenylation domains enables the efficient activation of non‐natural aromatic amino acids functionalized with azide and alkyne groups. The resulting 105‐fold switch in substrate specificity was achieved without appreciable loss of catalytic efficiency. Moreover, the effective communication of the modified A domains with downstream modules in dipeptide synthetases permitted incorporation of O‐propargyl‐L‐tyrosine into diketopiperazines both in vitro and in vivo, even in the presence of competing phenylalanine. Because azides and alkynes readily undergo bioorthogonal click reactions, reprogramming NRPSs to accept non‐natural amino acids that contain these groups provides a potentially powerful means of isolating, labeling, and modifying biologically active peptides.
Nanocrystalline‐Graphene‐Tailored Hexagonal Boron Nitride Thin Films
Authors: Lee Kang Hyuck , Shin Hyeon‐Jin , Kumar Brijesh , Kim Han Sol , Lee Jinyeong , Bhatia Ravi , Kim Sang‐Hyeob , Lee In‐Yeal , Lee Hyo Sug , Kim Gil‐Ho , Yoo Ji‐Beom , Choi Jae‐Young , Kim Sang‐Woo 
Published: September 2014

AbstractUnintentionally formed nanocrystalline graphene (nc‐G) can act as a useful seed for the large‐area synthesis of a hexagonal boron nitride (h‐BN) thin film with an atomically flat surface that is comparable to that of exfoliated single‐crystal h‐BN. A wafer‐scale dielectric h‐BN thin film was successfully synthesized on a bare sapphire substrate by assistance of nc‐G, which prevented structural deformations in a chemical vapor deposition process. The growth mechanism of this nc‐G‐tailored h‐BN thin film was systematically analyzed. This approach provides a novel method for preparing high‐quality two‐dimensional materials on a large surface.
Photocatalytic Hydrogen Production using Polymeric Carbon Nitride with a Hydrogenase and a Bioinspired Synthetic Ni Catalyst
Authors: Caputo Christine A. , Gross Manuela A. , Lau Vincent W. , Cavazza Christine , Lotsch Bettina V. , Reisner Erwin 
Published: September 2014

AbstractSolar‐light‐driven H2 production in water with a [NiFeSe]‐hydrogenase (H2ase) and a bioinspired synthetic nickel catalyst (NiP) in combination with a heptazine carbon nitride polymer, melon (CNx), is reported. The semibiological and purely synthetic systems show catalytic activity during solar light irradiation with turnover numbers (TONs) of more than 50 000 mol H2 (mol H2ase)−1 and approximately 155 mol H2 (mol NiP)−1 in redox‐mediator‐free aqueous solution at pH 6 and 4.5, respectively. Both systems maintained a reduced photoactivity under UV‐free solar light irradiation (λ>420 nm).
The Isomerization of Allylrhodium Intermediates in the Rhodium‐Catalyzed Nucleophilic Allylation of Cyclic Imines
Authors: Hepburn Hamish B. , Lam Hon Wai 
Published: September 2014

AbstractAllylrhodium species generated from potassium allyltrifluoroborates can undergo isomerization by 1,4‐rhodium(I) migration to give more complex isomers, which then react with cyclic imines to provide products with up to three new stereochemical elements. High enantioselectivities are obtained using chiral diene–rhodium complexes.
N‐Heterocyclic Carbene Catalyzed Cyclocondensation of α,β‐Unsaturated Carboxylic Acids: Enantioselective Synthesis of Pyrrolidinone and Dihydropyridinone Derivatives
Authors: Chen Xiang‐Yu , Gao Zhong‐Hua , Song Chun‐Yu , Zhang Chun‐Lin , Wang Zhi‐Xiang , Ye Song 
Published: September 2014

AbstractThe catalytic cyclocondensation of in situ activated α,β‐unsaturated carboxylic acids was developed. N‐heterocyclic carbenes efficiently catalyzed the generation of α,β‐unsaturated acyl azolium intermediates from α,β‐unsaturated carboxylic acids via in situ generated mixed anhydrides for the enantioselective [3+2] and [3+3] cyclocondensation with α‐amino ketones and alkyl(aryl)imines, respectively. The corresponding pyrrolidinones and dihydropyridinones were isolated in good yields with high to excellent enantioselectivities.