bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ergodic approximations via matrix regularization approach
Authors: Marino Giuseppe , Cianciaruso Filomena , Hussain Nawab 
Published: May 2015

AbstractIn this paper we use a matrix approach to approximate solutions of variational inequalities in Hilbert spaces. The methods studied combine new or well-known iterative methods (as the original Mann method) with regularized processes that involve regular matrices in the sense of Toeplitz. We obtain ergodic type results and convergence.
Beneficial effect of phosphatidylcholine supplementation in alleviation of hypomania and insomnia in a Chinese bipolar hypomanic boy and a possible explanation to the effect at the genetic level
Authors: Rao Shitao , Lam Marco H B , Wing Yun Kwok , Yim Larina C L , Chu Winnie C W , Yeung Venus S Y , Waye Mary M Y 
Published: May 2015

Abstract

Introduction
Recent studies indicated that supplementation of phosphatidylcholine has been found to be beneficial for psychiatric diseases and Diacylglycerol Kinase, Eta (DGKH) protein was involved in regulating the metabolism of phosphatidic acid and diacylglycerol. This study reported a case of a 16-year-old Chinese boy with bipolar hypomania symptoms receiving supplementation of phosphatidylcholine, and a genetic study of a risk variant of DGKH gene was performed in an attempt to provide an explanation for the potential beneficial effect of phosphatidylcholine supplementation.

Case description
We described a case of a 16-year-old boy with bipolar disorder, who suffered from monthly episodes of insomnia accompanied by hypomania for 5 months despite adherence to medication. After supplementation of phosphatidylcholine, he returned to a normal sleeping pattern and recovered from hypomania symptoms for approximately 14 months. Furthermore, genotyping results showed that this boy carries the risk genotype (G/C) in DGKH variant rs77072822 (adjusted p-value = 0.025 after 2000 permutation tests).

Discussion and evaluation
The 16-year-old boy appears to have benefited from the supplementation with phosphatidylcholine and recovered from hypomania symptoms. He carries a risk genotype in rs77072822 which lies in the first intron of DGKH gene that was mostly reported to be associated with bipolar disorder. Thus, this finding is consistent with the hypothesis that alleviating the phosphatidylcholine deficiencies might accompany with the risk variants of DGKH gene, which might improve the efficacies of such supplementation and design new treatment strategies for bipolar disorder.

Conclusions
This study illustrated that a 16-year-old boy with hypomania symptoms responded well to supplementation of phosphatidylcholine and the boy carries a risk genotype in DGKH gene for bipolar disorder, which provides a possible explanation for the boy’s beneficial effect at the genetic level.
Poverty alleviation by Zakah in a transitional economy: a small business entrepreneurial framework
Authors: Hoque Nazamul , Khan Mohammad Aktaruzzaman , Mohammad Kazi Deen 
Published: May 2015

Abstract
Around 3 billion people are living in poverty of which 35 % are from Muslim World (World Bank 2010). In this case, global Muslim community has prime role to address the injustice of global poverty through zakah as an Islamic faith-based institution and having potential annual fund of $139.32 billion in Muslim world. This study designed an explanatory sequential mixed method. For qualitative data, 17 managers were interviewed and 85 zakah recipients were purposively surveyed (disproportionate sampling) for quantitative purpose between August 1 and December 30, 2013. The results indicate that zakah has significant bearing on the conditions of zakah recipients and lie the foundation of developing small business entrepreneurship by mobilizing zakah as seed money (investment) and not as spent money (consumption). A five-phased process model underpinned by two well-grounded theories: Becker’s human capital theory and Kirkpatrick’s training evaluation taxonomy has been proposed for developing entrepreneurship having universal application. The model’s implications for alleviating poverty by governments, zakah management institutions, and policy makers also discussed in the paper.
JMSS-1: a new Martian soil simulant
Authors: Zeng Xiaojia , Li Xiongyao , Wang Shijie , Li Shijie , Spring Nicole , Tang Hong , Li Yang , Feng Junming 
Published: May 2015

Abstract
It is important to develop Martian soil simulants that can be used in Mars exploration programs and Mars research. A new Martian soil simulant, called Jining Martian Soil Simulant (JMSS-1), was developed at the Lunar and Planetary Science Research Center at the Institute of Geochemistry, Chinese Academy of Sciences. The raw materials of JMSS-1 are Jining basalt and Fe oxides (magnetite and hematite). JMSS-1 was produced by mechanically crushing Jining basalt with the addition of small amounts of magnetite and hematite. The properties of this simulant, including chemical composition, mineralogy, particle size, mechanical properties, reflectance spectra, dielectric properties, volatile content, and hygroscopicity, have been analyzed. On the basis of these test results, it was demonstrated that JMSS-1 is an ideal Martian soil simulant in terms of chemical composition, mineralogy, and physical properties. JMSS-1 would be an appropriate choice as a Martian soil simulant in scientific and engineering experiments in China’s Mars exploration in the future.
NK cells inhibit humoral immunity by reducing the abundance of CD4+ T follicular helper cells during a chronic virus infection
Authors: Cook Kevin D , Kline Hannah C , Whitmire Jason K 
Published: May 2015

Abstract
There is a need to understand better how to improve B cell responses and immunity to persisting virus infections, which often cause debilitating illness or death. People with chronic virus infection show evidence of improved virus control when there is a strong neutralizing antibody response, and conversely, B cell dysfunction is associated with higher viral loads. We showed previously that NK cells inhibit CD4+ and CD8+ T cell responses to disseminating LCMV infection and that depletion of NK cells attenuates chronic infection. Here, we examined the effect of NK cell depletion on B cell responses to LCMV infection in mice. Whereas mice infected acutely generated a peak level of antibody soon after the infection was resolved, mice infected chronically showed a continued increase in antibody levels that exceeded those after acute infection. We found that early NK cell depletion rapidly increased virus-specific antibody levels to chronic infection, and this effect depended on CD4+ T cells and was associated with elevated numbers of CXCR5+CD4+ TFH cells. However, the NK cell-depleted mice controlled the infection and by 1 mo pi, had lower TFH cell numbers and antibody levels compared with mice with sustained infection. Finally, we show that NK cell depletion improved antiviral CD8+ T cell responses only when B cells and virus-specific antibody were present. Our data indicate that NK cells diminish immunity to chronic infection, in part, by suppressing TFH cell and antibody responses.
Validation and Development of a Modified Breast Graded Prognostic Assessment As a Tool for Survival in Patients With Breast Cancer and Brain Metastases
Authors: Subbiah Ishwaria M. , Lei Xiudong , Weinberg Jeffrey S. , Sulman Erik P. , Chavez-MacGregor Mariana , Tripathy Debu , Gupta Rohan , Varma Ankur , Chouhan Jay , Guevarra Richard P. , Valero Vicente , Gilbert Mark R. , Gonzalez-Angulo Ana M. 
Published: May 2015

Purpose Several indices have been developed to predict overall survival (OS) in patients with breast cancer with brain metastases, including the breast graded prognostic assessment (breast-GPA), comprising age, tumor subtype, and Karnofsky performance score. However, number of brain metastases—a highly relevant clinical variable—is less often incorporated into the final model. We sought to validate the existing breast-GPA in an independent larger cohort and refine it integrating number of brain metastases. Patients and Methods Data were retrospectively gathered from a prospectively maintained institutional database. Patients with newly diagnosed brain metastases from 1996 to 2013 were identified. After validating the breast-GPA, multivariable Cox regression and recursive partitioning analysis led to the development of the modified breast-GPA. The performances of the breast-GPA and modified breast-GPA were compared using the concordance index. Results In our cohort of 1,552 patients, the breast-GPA was validated as a prognostic tool for OS (P < .001). In multivariable analysis of the breast-GPA and number of brain metastases (> three v ≤ three), both were independent predictors of OS. We therefore developed the modified breast-GPA integrating a fourth clinical parameter. Recursive partitioning analysis reinforced the prognostic significance of these four factors. Concordance indices were 0.78 (95% CI, 0.77 to 0.80) and 0.84 (95% CI, 0.83 to 0.85) for the breast-GPA and modified breast-GPA, respectively (P < .001). Conclusion The modified breast-GPA incorporates four simple clinical parameters of high prognostic significance. This index has an immediate role in the clinic as a formative part of the clinician's discussion of prognosis and direction of care and as a potential patient selection tool for clinical trials.
Polymorphisms in Genes Related to Oxidative Stress Are Associated With Inferior Cognitive Function After Therapy for Childhood Acute Lymphoblastic Leukemia
Authors: Cole Peter D. , Finkelstein Yaron , Stevenson Kristen E. , Blonquist Traci M. , Vijayanathan Veena , Silverman Lewis B. , Neuberg Donna S. , Sallan Stephen E. , Robaey Philippe , Waber Deborah P. 
Published: May 2015

Purpose Survivors of childhood acute lymphoblastic leukemia (ALL) exhibit increased rates of neurocognitive deficits. This study was conducted to test whether interpatient variability in neurocognitive outcomes can be explained by polymorphisms in candidate genes conferring susceptibility to neurocognitive decline. Methods Neurocognitive testing was conducted in 350 pediatric leukemia survivors, treated on Dana-Farber Cancer Institute ALL Consortium Protocols 95-01 or 00-01. Genomic DNA was isolated from bone marrow collected at remission. Candidate polymorphisms were selected on the basis of prior literature, targeting genes related to drug metabolism, oxidative damage, altered neurotransmission, neuroinflammation, and folate physiology. Single nucleotide polymorphisms were detected using either a customized multiplexed Sequenom MassARRAY assay or polymerase chain reaction–based allelic discrimination assays. Multivariable logistic regression models were used to estimate the effects of genotype on neurocognitive outcomes, adjusted for the effects of demographic and treatment variables. False-discovery rate correction was made for multiple hypothesis testing, indicated as a Q value. Results Inferior cognitive or behavioral outcomes were associated with polymorphisms in three genes related to oxidative stress and/or neuroinflammation: NOS3 (IQ, Q = 0.008; Vocabulary Q = 0.011; Matrix Reasoning Q = 0.008), SLCO2A1 (IQ Q = 0.043; Digit Span Q = 0.006; Block Design Q = 0.076), and COMT (Behavioral Assessment System for Children-2 Attention Q = 0.080; and Hyperactivity Q = 0.084). Survivors homozygous for NOS3 894T, with at least one SLCO2A1 variant G allele or with at least one GSTP1 variant allele, had lower mean estimated IQ scores than those without these genotypes. Conclusion These data are consistent with the hypothesis that oxidative damage contributes to chemotherapy-associated neurocognitive decline among children with leukemia.
Muscle contractile properties as an explanation of the higher mean power output in marmosets than humans during jumping
Authors: Plas Rogier L.C. , Degens Hans , Meijer J.P. (Peter) , de Wit G.M.J. , Philippens Ingrid H.C.H.M. , Bobbert Maarten F. , Jaspers Richard T. 
Published: May 2015

The muscle mass specific mean power output (PMMS,mean) during push-off in jumping is in marmosets (Callithrix jacchus) more than twice that in humans. In the present study it was tested whether this is attributable to differences in muscle contractile properties.
In biopsies of marmoset m. vastus lateralis (VL) and m. gastrocnemius medialis (GM) (n=4) fiber type distribution was assessed using fluorescent immunohistochemistry. In single fibers from four marmoset and nine human VL biopsies the force-velocity characteristics were determined.
Marmoset VL contained almost exclusively fast muscle fibers (&gt;99.0%), of which 63% were type IIB and 37% hybrid fibers, fibers containing multiple myosin heavy chains. GM contained 9% type I fibers, 44% type IIB and 47% hybrid muscle fibers. The proportions of fast muscle fibers in marmoset VL and GM were substantially larger than those reported in the corresponding human muscles. The curvature of the force-velocity relationships of marmoset type IIB and hybrid fibers was substantially flatter than that of human type I, IIA, IIX and hybrid fibers resulting in substantially higher muscle fiber mass specific peak powers (PFMS,peak). Muscle mass specific peak power output (PMMS,peak) of marmoset whole VL and GM, estimated from their fiber type distributions and force-velocity characteristics were more than twice the estimates for the corresponding human muscles.
Since the relative difference in estimated PMMS,peak between marmoset and human is similar to that PMMS,mean during push-off in jumping, it is likely that the difference in in vivo mechanical output between humans and marmosets is attributable to differences in muscle contractile properties.
Diverse dose-response effects of yolk androgens on embryo development and nestling growth in a wild passerine
Authors: Muriel Jaime , Pérez-Rodríguez Lorenzo , Puerta Marisa , Gil Diego 
Published: May 2015

Avian egg yolks contain various amounts of maternally derived androgens that can modify offspring phenotype and adjust their development to posthatching environment. Seemingly adaptive variation in yolk androgen levels with respect to breeding density conditions or male attractiveness has been found in numerous studies. One important consideration that has been overlooked in previous research is the likely non-linear nature of hormone effects. To examine possible complex dose-response effects of maternal androgens on chick development, we experimentally administered three different androgen doses of the naturally-occurring mixture of yolk testosterone and androstenedione to spotless starling eggs (Sturnus unicolor). We found that yolk androgens show a non-linear dose-response pattern for several traits. Thus, androgens had a stimulatory effect on hatching body mass and nestling skeletal growth, but maximum values were found at intermediate doses, whereas our highest dose resulted in a decrease. However, the opposite U-shaped effect was found on nestling body mass. We also detected linear negative and positive effects on embryonic development period and nestling gape width, respectively. Our results suggest differential tissue responsiveness to yolk androgens, which may result in compromises in maternal allocation to produce adapted phenotypes. Due to the non-linear dose-response pattern, future investigations should carefully consider a wide range of concentrations, since the balance of costs and benefits may strongly differ depending on concentration.
Intrinsically Atomic-oxygen-resistant POSS-containing Polyimide Aerogels: Synthesis and Characterization
Authors: Fang Guangqiang , Li Hua , Liu Jingang , Ni Hongjiang , Yang Haixia , Yang Shiyong 
Published: May 2015

Abstract
A series of polyimide aerogels with intrinsically atomic-oxygen-resistant features have been synthesized. For this purpose, 3,3′,4,4′-biphenyltetracarboxylic dianhydride (s-BPDA) was copolymerized with 2,2′-dimethylbenzidine (DMBZ) and a polyhedral oligomeric silsesquioxane (POSS)-containing aromatic diamine, N-[(heptaisobutylPOSS)propyl]-3,5-diaminobenzamide (DA-POSS), with octa(aminophenyl)silsesquioxane (OAPS) as the crosslinker via sol–gel procedures followed by supercritical carbon dioxide (scCO2) drying treatments.
Synthesis of Thieno[3,2-b]benzofurans by Palladium-catalyzed Intramolecular C–H/C–H Coupling
Authors: Kaida Hiroyuki , Satoh Tetsuya , Hirano Koji , Miura Masahiro 
Published: May 2015

Abstract
The intramolecular C–H/C–H coupling of 3-aryloxythiophenes and 3-aryloxybenzo[b]thiophenes has been found to occur effectively in the presence of Pd(TFA)2 and AgOAc as catalyst and oxidant, respectively, to afford the corresponding cyclized products, thieno[3,2-b]benzofurans and [1]benzothieno[3,2-b]benzofurans.
Development of an Algorithm to Classify Colonoscopy Indication from Coded Health
Care Data
Authors: Adams Kenneth F. , Johnson Eric A. , Chubak Jessica , Kamineni Aruna , Doubeni Chyke A. , Buist Diana S.M. , Williams Andrew E. , Weinmann Sheila , Doria-Rose V. Paul , Rutter Carolyn M. 
Published: May 2015

Introduction: Electronic health data are potentially valuable resources for
evaluating colonoscopy screening utilization and effectiveness. The ability to
distinguish screening colonoscopies from exams performed for other purposes is critical
for research that examines factors related to screening uptake and adherence, and the
impact of screening on patient outcomes, but distinguishing between these indications in
secondary health data proves challenging. The objective of this study is to develop a
new and more accurate algorithm for identification of screening colonoscopies using
electronic health data.Methods: Data from a case-control study of colorectal cancer with
adjudicated colonoscopy indication was used to develop logistic regression-based
algorithms. The proposed algorithms predict the probability that a colonoscopy was
indicated for screening, with variables selected for inclusion in the models using the
Least Absolute Shrinkage and Selection Operator (LASSO).Results: The algorithms had
excellent classification accuracy in internal validation. The primary, restricted model
had AUC= 0.94, sensitivity=0.91, and specificity=0.82. The secondary, extended model had
AUC=0.96, sensitivity=0.88, and specificity=0.90.Discussion: The LASSO approach enabled
estimation of parsimonious algorithms that identified screening colonoscopies with high
accuracy in our study population. External validation is needed to replicate these
results and to explore the performance of these algorithms in other settings.
Reviews
Authors: Brooking Tom , Biskup Przemyslaw , Bracefield Hilary , David-Ives Corinne , Carter Lynette , Russell Khyla , Tabe Tammy , Sofo Giuseppe , Aitken Tom , Biskup Przemyslaw , Tokolyova Tatiana , Meaher Augustine , Sedgwick Laura , Moura-Koçoglu Michaela , Leask Rognvald 
Published: May 2015

Abstract
Encounters: The Creation of New Zealand. A History, Paul Moon (2013) Auckland: Penguin New Zealand, 432 pp., ISBN 978 0 1435 6850 6 (hbk), NZ$55
Changing Times: New Zealand since 1945, Jenny Carlyon and Diane Morrow (2013) Auckland: Auckland University Press, 520 pp., ISBN 978 1 8694 0782 7 (pbk), NZ$49.99
Webs of Empire: Locating New Zealand’s Colonial Past, Tony Ballantyne (2012) Wellington: Bridget Williams Books, 374 pp., ISBN 978 1 9271 3143 5 (pbk), NZ$49.99
Flying Kiwis: A History of the OE, Jude Wilson (2014) Dunedin: Otago University Press, 296 pp., ISBN 978 1 8775 7826 7 (pbk), NZ$44.99
Kerikeri Mission and Kororipo Pa: An Entwined History, Angela Middleton (2013) Dunedin: Otago University Press, 76 pp., ISBN 978 1 8775 7834 2 (pbk), NZ$29.95
Ko te whenua te utu / Land is the price: Essays on Maori History, Land and Politics, M. P. K. Sorrenson (2014) Auckland: Auckland University Press, 344 pp., ISBN 978 1 8694 0810 7 (pbk), NZ$49.99
The Spirit of Maori Leadership, Selwyn Katene (2013) Wellington: Huia, 180 pp., ISBN 978 1 7755 0121 3 (pbk), NZ$45
Greed and Grievance: Ex-militants’ Perspectives on the Conflict in Solomon Islands, 1998–2003, Matthew Allen (2013) Honolulu: University of Hawai’i Press, 243 pp., ISBN 978 0 8248 3854 6 (pbk), US$55
Mystery Islands: Discovering the Ancient Pacific, Tom Koppel (2012) Suva: University of the South Pacific Press, 345 pp., ISBN 978 9 8201 0888 2 (pbk), US$25
Ancient Religions of the Austronesian World: From Australasia to Taiwan, Julian Baldick (2013) London: I.B. Tauris, 256 pp., ISBN 978 1 7807 6366 8 (hbk), £58
The Pacific Island in China’s Grand Strategy: Small States, Big Games, Jian Yang (2011) Basingstoke: Palgrave Macmillan, 254 pp., ISBN 978 0 2301 1323 7 (hbk), £64
No Ordinary Deal: Unmasking the Transpacific Partnership Free Trade Agreement, Jane Kelsey (ed.) (2010) Wellington: Bridget Williams Books, 220 pp., ISBN 978 1 8772 4250 2 (pbk), NZ$39.99
Greece, Crete, Stalag, Dachau: A New Zealand Soldier’s Encounters with Hitler’s Army, Jack Elworthy (2014) Wellington: Awa Press, 256 pp., ISBN 978 1 9272 4912 3 (pbk), NZ$40
Transnational Film Culture in New Zealand, Simon Sigley (2013) Bristol: Intellect, 208 pp., ISBN 978 1 8415 0660 9 (pbk), £20
Intersecting Identities: Ethnicity, Gender, and Sexuality in Contemporary Fiction from Aotearoa New Zealand, Katharina Luh (2013) Trier, Germany: WVT, 555 pp., ISBN 978 3 8682 1433 8 (pbk), ¤58.50
The Lonely and the Alone: The Poetics of Isolation in New Zealand Fiction, Doreen D’Cruz and John C. Ross (2011) Amsterdam: Rodopi, 407 pp., ISBN 978 9 0420 3474 7 (hbk), €102
On The Convergence of Domain Decomposition Algorithm for The Body with Thin Inclusion
Authors: Styahar Andriy , Savula Yarema 
Published: May 2015

Abstract
We consider a coupled 3D model that involves computation of the stress-strain state for the body with thin inclusion. For the description of the stress-strain state of the main part, the linear elasticity theory is used. The inclusion is modelled using Timoshenko theory for shells. Therefore, the dimension of the problem inside the inclusion is decreased by one. For the numerical solution of this problem we propose an iterative domain decomposition algorithm (Dirichlet-Neumann scheme). This approach allows us to decouple problems in both parts and preserve the structure of the corresponding matrices. We investigate the convergence of the aforementioned algorithm and prove that the problem is well-posed.
Time delay and Lagrangian approximation for Navier–Stokes flow
Authors: Asanalieva Nazgul , Heutling Carolin , Varnhorn Werner 
Published: May 2015

Abstract
We consider the nonstationary nonlinear Navier–Stokes equations
describing the motion of a viscous incompressible fluid flow for

0
<
t
≤
T

${0 &lt; t
\le T}$

in a bounded domain

Ω
⊆

ℝ
3

${\Omega \subseteq \mathbb {R}^3}$

with sufficiently smooth boundary

∂
Ω

${\partial \Omega }$

. We use a particle method in connection with a time delay to approximate the nonlinear convective term by a single central Lagrangian difference quotient constructed from autonomous systems of ordinary differential equations. We show that the resulting approximate Navier–Stokes system has a uniquely determined global solution satisfying the energy equation and having a high degree of regularity uniformly in time. Moreover, we prove that the sequence of
approximate solutions has an accumulation point satisfying the
Navier–Stokes equations in a weak sense and the energy inequality.
Two constant sign solutions for a nonhomogeneous Neumann boundary value problem
Authors: Klimczak Liliana 
Published: May 2015

Abstract We consider a nonlinear Neumann problem with a nonhomogeneous elliptic differential operator. With some natural conditions for its structure and some general assumptions on the growth of the reaction term we prove that the problem has two nontrivial solutions of constant sign. In the proof we use variational methods with truncation and minimization techniques.