bluuebunny/crossref_metadata_2025_split huggingface dataset:
Qualitative Exploration of the Needs of Pregnant Women to Manage the Fear of Childbirth
Authors: Bakhteh Azam , Jaberghaderi Nasrin , Kamravamanesh Mastaneh , Kolivand Mitra , Rezaei Mansour , Motaghi Zahra 
Published: August 2024

Background:
Some women experience the Fear of Childbirth (FOC) during pregnancy, labor, and birth which can have consequences for their health and well-being. To provide the right conditions for having a positive experience of childbirth, the needs of pregnant women must be correctly recognized. The present study was conducted with the aim of investigating the needs of women in managing the FOC with a qualitative design.

Materials and Methods:
This qualitative study was conducted using conventional content analysis from January to November 2021. To this aim, 15 pregnant women, 21 healthcare providers, and four maternal health policymakers were purposefully selected from Kermanshah health centers, with maximum diversity. Data were collected through in-depth semi-structured interviews. Data accuracy was guaranteed using Lincoln and Guba criteria. The MAXQDA software was used for data analysis.

Results:
From the analysis of the data obtained from the interviews, three main categories emerged concerning the needs of mothers to properly manage the FOC: “need to provide awareness and empowerment of mother and family,” and “the need to pay attention to the mental health of pregnant women,” and “supporting needs (seeking support).”

Conclusions:
Identifying and paying attention to woman's needs in the areas of education, mental health, and support can help them manage crisis-ridden situations, including the FOC. In response to the needs of mothers to empower them in managing the FOC, it is recommended to formulate special guidelines in this field.
Do Health Literacy and Awareness of Polycystic Ovary Syndrome Predict the Lifestyle Choices of Arabic-Speaking Female University Students
Authors: Al Maamari Reham , Al Hashmi Iman , Al Dhuli Al Anoud , Al Abri Ashjan , Al Ghaithi Asma , Al Sinan Sakeena 
Published: August 2024

Background:
Considering the increasing prevalence of Polycystic Ovarian Syndrome (PCOS) and its related complications—such as obesity, cardiovascular diseases, and infertility—in the Middle East, it is imperative to create sufficient public awareness about this issue. Accordingly, the potential link between PCOS awareness and health literacy level with the lifestyle choices of Arabic-speaking female university students was examined in this cross-sectional study.

Materials and Methods:
This research was conducted in the Sultanate of Oman and involved 446 Arabic-speaking female university students, who completed a self-administered online questionnaire, Single Item Literacy Screener, and PCOS Awareness Tool.

Results:
The findings showed that, while 53.50% of the study participants had inadequate health literacy, 79.80% demonstrated an acceptable level of PCOS awareness. However, this did not seem to influence their lifestyle, given that 59.20% of the respondents were physically inactive and 83.30% regularly consumed fast food. Regression analysis results nonetheless revealed that health literacy and PCOS awareness were significant predictors of lifestyle choices (F2,44 = 5.98, p < 0.05, 95% CI [4.44–5.35]).

Conclusions:
The Arabic-speaking female university students' health literacy level and PCOS awareness are significant predictors of their lifestyle choices. Thus, the policymakers in the Arab region need to develop effective strategies aimed at PCOS prevention, focusing specifically on raising public awareness about PCOS and its negative consequences on female reproductive health. In addition, university administrators should ensure the availability of healthy food choices at their campuses as well as opportunities for physical activity to promote healthy lifestyle among all students.
Midwives' Voices on Early Initiation of Antenatal Care Following a Positive Gravindex Test: A Qualitative Study
Authors: Shinyawani Rhulani S. , Malwela Thivhulawi N. , Maputle Maria S. 
Published: August 2024

Background:
Early Antenatal Care (ANC) initiation is aimed at improving maternal and perinatal health outcomes through the identification of complications and determining the level of care needed. This study aimed to determine the voices of midwives on the provision of early initiation of ANC following positive gravindex.

Materials and Methods:
The phenomenology approach underpinned the study. The participants included midwives providing ANC at health facilities under Tshino–Mutsha local area in May–December 2020. Nonprobability, purposive sampling was used to select four clinics and to sample 20 midwives. Semistructured face-to-face, in-depth interviews were conducted using an interview guide. Data saturation was reached at Participant 15; however, the researcher continued until Participant 20. Trustworthiness was ensured and ethical principles were adhered to. Data analysis was done using Tesch's open coding approach.

Results:
Two themes and seven subthemes emerged, as challenges related to the provision of midwifery practice and to pregnant women. The seven subthemes were the shortage of resources, poor support of midwives, poor adherence to the available protocol for the provision of ANC, blaming of midwives by management and community, late ANC booking by pregnant women, denial of pregnancy by young women ignorance leading to a general resistance to ANC instructions, hence late booking

Conclusions:
It was concluded that shortage of human and material resources hindered the initiation of early ANC to detect, prevent, and manage the existing and potential causes of maternal and newborn mortality and morbidity.
Nurses' Experience of Occupational Alienation in the Clinical Setting: A Content Analysis
Authors: Salehian Maryam , Goli Hamideh , Yazdimoghaddam Hamideh 
Published: August 2024

Background:
Job alienation of nurses leads to adverse consequences such as occupational dysfunction and low quality of health-care services provided by these individuals to patients. This study aimed to explain nurses' experience of occupational alienation in the clinical setting.

Materials and Methods:
This qualitative study was conducted using the content analysis method. Data were collected via 18 in-depth and semistructured interviews from nurses working in the hospitals in Sabzevar, Iran. The participants were selected via purposive sampling and continued till data saturation. The obtained data were simultaneously analyzed using conventional qualitative content analysis.

Results:
The qualitative analysis of data content led to the extraction of the themes that reflected the nurses' experience of occupational alienation in the clinical environment. After the transcription of each interview, the obtained data were broken down into codes in the form of sentences and paragraphs related to the main concept. The codes were reviewed several times and the relevant semantic unit codes were written down and classified based on conceptual and semantic similarity. Qualitative data analysis led to the emergence of 260 initial codes, 120 subcategories, 30 main categories, and 6 themes. Finally, the main theme of the “nursing gradual separation from caring and clinical aspect” was extracted.

Conclusions:
According to the results, occupational alienation reduces the quality of patient care, weakens nurses, and reduces the continuity of their effective and active presence in the provision of care services and clinical decision-making. Therefore, managerial and organizational interventions are required to address this issue.
Is Web-Based Program Effective on Self-Care Behaviors and Glycated Hemoglobin in Patients with Type 2 Diabetes: A Randomized Controlled Trial
Authors: Eghtedari Maryam , Goodarzi-Khoigani Masoomeh , Shahshahani Maryam Sadat , Javadzade Homamodin , Abazari Parvaneh 
Published: August 2024

Background:
Diabetes Self-Management Education and Support (DSMES) as a framework focuses on seven self-care behaviors. Moreover, technology-assisted self-care education is increasingly suggested for patients with Type 2 Diabetes Mellitus (T2DM). Therefore, we examined the effect of a web-based program on self-care behaviors and glycated hemoglobin values in patients with diabetes mellitus.

Materials and Methods:
This randomized controlled clinical trial was conducted at Alzahra Hospital in Isfahan, Iran, between April and November 2020 and included 70 patients with T2DM. Data were collected using a questionnaire that included a demographic information section and a diabetes self-management section with 21 questions on a Likert scale. Fasting blood samples (2.50 ml) were collected before and after the interventions to measure HbA1c levels. The study intervention involved a web-based program that included multimedia educational content (such as videos, lectures, educational motion graphics, text files, posters, and podcasts) presented in seven sections based on DSMES over a 21-day period with monitoring by an instructor.

Results:
The mean scores for healthy eating (F = 3.48, p = 0.034) and medication adherence (F = 6.70, p < 0.001) significantly increased in the interventional group, while the mean scores for being active, monitoring, reducing risks, problem-solving, and healthy coping did not significantly change. Additionally, the mean differences in HbA1c values significantly improved in the interventional group compared to the control (F = 5,1, p = 0.026).

Conclusions:
A web-based program in accordance with DSMES improved HbA1c levels and increased scores for healthy eating and medication adherence in patients with T2DM. However, further research with larger sample sizes and qualitative interviews is needed.
To assess the effect of selected locally available beverages on salivary pH, flow rate, and oral clearance rate among adults
Authors: Virk Jasleen , Malhan Sunil , Sandhu Gursandeep Kaur , Sood Himanshu , Ishita  , Prabhakar Danish 
Published: August 2024

Aim:
The aim of this study is to assess the effect of selected locally available beverages on salivary pH, flow rate, and oral clearance rate among adults.

Materials and Methods:
A quantitative diagnostic method for dental caries would improve oral health, which directly affects the quality of life. The pH scale measures how acidic or basic a solution is, with 7 being neutral. When the pH of plaque drops below normal, or <5.5, the acidity starts to dissolve minerals and destroy the tooth’s enamel. This clinical trial will be conducted on 40 subjects. Test beverages will be Red Bull, mixed fruit juice, tea, and sweetened milk. Unstimulated salivary samples will be collected for each study subject at least 1 h after their breakfast. After the collection of baseline salivary samples, the subjects will be given one beverage to drink, and then stimulated saliva samples will be collected at fixed time intervals. A digital pH meter will be used to measure the pH at every step.

Statistical Analysis:
This will be carried out using SPSS version 17, one-way ANOVA, and post hoc Tukey’s test will be applied in the statistical tests.

Results:
The maximum drop in pH was seen in the case of carbonated beverage (Red Bull), the oral clearance for all the liquid food items was achieved at 14 minutes.

Conclusions:
Liquids had a considerable cariogenic and erosive potential despite their quick clearance from the mouth cavity. it is always recommended to limit beverage consumption to maintain good dental health.
Comparative evaluation of the osteogenic capacity of second-generation platelet concentrates on dental pulp stem cells – An ex vivo study
Authors: Panda Bandana , Patri Gaurav , Jena Debkant , Behera Ranjan Rashmi , Agarwal Vanshika , Gupta Aditi 
Published: August 2024

Introduction:
Clinical evidence of platelet-rich fibrin (PRF) benefits on bone repair is still emerging, prompting researchers to experiment with different PRF formulations as osteoconductive scaffolds.

Aims:
This study compared the osteoconductive effects of injectable PRF (i-PRF) and leukocyte-rich PRF (L-PRF) on the differentiation of dental pulp stem cells (DPSCs) into osteoblasts.

Materials and Methods:
Blood samples were collected from the volunteers to prepare L-PRF and i-PRF conditioned media (CM) by centrifugation. DPSCs were isolated from impacted third molars and cultured. Proliferation of DPSCs in response to L-PRF and i-PRF was assessed by MTT (3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay. Osteoinductive potential was evaluated through alkaline phosphatase (ALP) activity, alizarin red S (ARS) staining, growth factor levels (vascular endothelial growth factor [VEGF], transforming growth factor [TGF-beta]), and cytokine expression (interleukin 6 [IL-6], IL-8) after 7 days.

Results:
MTT assay results showed that both L-PRF and i-PRF increased DPSC proliferation relative to the control group. After 7 days in L-PRF and i-PRF CM, DPSCs exhibited increased ALP activity, higher red-colored calcium deposits with ARS staining, and elevated levels of VEGF and TGF-beta. In addition, higher concentrations of inflammatory cytokines IL-6 and IL-8 were observed in both L-PRF and i-PRF compared to the control.

Conclusions:
Using both L-PRF and i-PRF as scaffolds can enhance the osteoinductive ability of stem cells, offering a potential strategy for regenerative therapies.
Insulin-like growth factor 2 targets IGF1R signaling transduction to facilitate metastasis and imatinib resistance in gastrointestinal stromal tumors
Authors: Li De-Gang , Jiang Jia-Peng , Chen Fan-Ye , Wu Wei , Fu Jun , Wang Gong-He , Li Yu-Bo 
Published: August 2024

BACKGROUND
Gastrointestinal stromal tumors (GISTs) are typical gastrointestinal tract neoplasms. Imatinib is the first-line therapy for GIST patients. Drug resistance limits the long-term effectiveness of imatinib. The regulatory effect of insulin-like growth factor 2 (IGF2) has been confirmed in various cancers and is related to resistance to chemotherapy and a worse prognosis.
AIM
To further investigate the mechanism of IGF2 specific to GISTs.
METHODS
IGF2 was screened and analyzed using Gene Expression Omnibus (GEO: GSE225819) data. After IGF2 knockdown or overexpression by transfection, the phenotypes (proliferation, migration, invasion, apoptosis) of GIST cells were characterized by cell counting kit 8, Transwell, and flow cytometry assays. We used western blotting to evaluate pathway-associated and epithelial-mesenchymal transition (EMT)-associated proteins. We injected transfected cells into nude mice to establish a tumor xenograft model and observed the occurrence and metastasis of GIST.
RESULTS
Data from the GEO indicated that IGF2 expression is high in GISTs, associated with liver metastasis, and closely related to drug resistance. GIST cells with high expression of IGF2 had increased proliferation and migration, invasiveness and EMT. Knockdown of IGF2 significantly inhibited those activities. In addition, OE-IGF2 promoted GIST metastasis in vivo in nude mice. IGF2 activated IGF1R signaling in GIST cells, and IGF2/IGF1R-mediated glycolysis was required for GIST with liver metastasis. GIST cells with IGF2 knockdown were sensitive to imatinib treatment when IGF2 overexpression significantly raised imatinib resistance. Moreover, 2-deoxy-D-glucose (a glycolysis inhibitor) treatment reversed IGF2 overexpression-mediated imatinib resistance in GISTs.
CONCLUSION
IGF2 targeting of IGF1R signaling inhibited metastasis and decreased imatinib resistance by driving glycolysis in GISTs.
Corporate Social Responsibility (CSR) Practices of Shariaconsumer Cooperatives for Sustainable Development Goals (SDGS) Ethical Perspective
Authors: Zulfiani Sri Mega Indah Umi , Muthoifin  , Rosyadi Imron 
Published: August 2024

Objectives: This study aims to explain (1) Islamic business ethics and corporate responsibility for sustainable development goals, as well as (2) Corporate Social Responsibility (CSR) practices in the BTM Mulia Babat KKS in the context of Islamic business ethics.

Theoretical Framework: Islamic business ethics, which includes the values of honesty, fairness, and belonging, are considered essential to achieving business success. CSR is a corporate social responsibility that aims to increase corporate value and shareholder welfare. With a commitment to sustainable economic development, CSR integrates social responsibility in business operations. The framework of this research relates the implementation of Islamic business ethics to CSR practices, as well as how this impacts the company's value and stakeholder well-being.

Method: This study uses a qualitative approach with a type of field research. Data was collected through observations, interviews, and documentation related to CSR practices at KKS BTM Mulia Babat.

Results and Discussion: The results of the study show that: Islamic business ethics has five basic axioms: unity, balance, free will, virtue, and responsibility. The implementation of CSR at KKS BTM Mulia Babat has been carried out by the principles of Islamic business ethics. This includes responsibility to consumers, employees, investors, and the environment.

Research Implications: The findings of this study indicate that the application of Islamic business ethics in CSR can increase corporate value and shareholder welfare and contribute to sustainable economic development. In addition, it can be a model for other companies to integrate Islamic business ethics into their CSR practices.

Novelty/Originality: The uniqueness of this research lies in the combination of the concept of Islamic business ethics with CSR practices in the context of the BTM Mulia Babat KKS company. This research provides new insights into how Islamic values can be effectively integrated in modern business operations to achieve better social and environmental well-being.
Problematic Land Buying and Selling Transactions
Authors: Uktolseja Novyta , Dyastuti Risqi Mumpuni , Berlianty Teng , Demmatacco Triska 
Published: August 2024

Introduction: Land ownership has become a primary need, but in the process of land ownership there are still problems. Basically, the acquisition of land rights according to the Decree of the Minister of Agrarian Affairs Number 21 of Article 1 Point 1, the acquisition of land is carried out by transferring land rights or through the delivery of release of land rights followed by granting rights. But this activity is not carried out in its entirety so that it will cause problems in granting rights to the community. Purposes of the Research: This research was conducted in Sanahu Village, Elpaputih District, West Seram Regency. This village prioritizes and gives importance to matters relating to customary land. However, based on the dinamics of the community, transactions carried out by the community should be carried out in accordance with the provisions of the legislation governing land registration in order to obtain legal certainty in the transactions carried out and aim for orderly administration in land sector. Methods of the Research: This research method is empirical juridical research that uses primary and secondary data. The legal materials used are primary legal materials, secondary legal materials with questionnaire and interview methods, data collection techniques with literature studies and field studies. Data processing and analysis techniques use descriptive analytical data analysis by identifying, classifying, then analyzing and describing according to the hierarchy. Results of the Research: Based on have not carried out the first land the results of the interviews, it is known that some people in Sanahu village do not know about the sale and purchase practices that should be taken in order to obtain legal certainty from the sale and purchase transactions carried out. This should be done based on the provisions of Article 19 paragraph 2 of the UUPA, Article 37 of PP 24 of 1997 concerning land registration. As a result, in the event of problems related to previous land transactions, the community had to resolve themselves in a family manner, either without or with assistance from local officials. As a result, the people of Sanahu village have not carried out the initial registration and maintenance of land registration data properly. Because land administration is not orderly, if there are land issues in transactions carried out either by transferring rights or encumbering rights, there will be problems in the future and limit land owners in carriying out legal actions.
How do socioeconomic factors affect the development of adolescent-onset drug use disorders?
Authors: Wang Ziyue , Martins Silvia 
Published: August 2024

Illicit drug use has been a significant issue among adolescents (aged 10 to 19 years). This review investigates the intricate relationship between socioeconomic factors and adolescent-onset illicit drug use in both the United States and Brazil. These socioeconomic factors were categorized into three primary domains: home life, community, and school. At the home level, households grappling with issues such as parental substance abuse, mental health challenges, or financial hardships are notably associated with adolescent drug use. Parental education levels emerge as a critical determinant, with lower education linked to an increased risk of drug use among adolescents. Furthermore, family dysfunction and exposure to adverse childhood experiences (ACEs) , also escalate the likelihood of early drug experimentation. At the community level, poverty and neighborhood disorganization play a pivotal role in adolescent drug use. Adolescents residing in economically disadvantaged communities face heightened vulnerability due to elevated stress and crime, often resorting to illicit drugs as a coping mechanism. The school environment also plays a crucial role in shaping drug use through peer influence. In dysfunctional homes, adolescents seek support outside the family, forming vulnerable connections with peers engaged in substance use. Understanding the intricate association of these socioeconomic factors is imperative for policymakers, healthcare professionals, and educators. Targeted interventions should be developed to curtail the prevalence of adolescent substance use and foster the overall well-being of young individuals in society.
Corrosion Behavior of FeCoNiCrAl High-Entropy Alloy in Molten NaNO3-KNO3
Authors: Lu Huayi , Wang Yanli 
Published: August 2024

Molten nitrates are the main heat transfer fluid (HTF) for concentrated solar power (CSP) systems. However, due to the instability of molten nitrates at high temperatures, the corrosiveness of the molten nitrates poses high requirements for the structural material used in CSP. Therefore, it is urgent to develop highly corrosion-resistant materials. In this study, the corrosion behavior of FeCoNiCrAl high entropy alloys (HEA) in molten NaNO3-KNO3 (60 wt% to 40 wt%) under argon at 600°C is investigated by mass loss and electrochemical methods. The results show that the FeCoNiCrAl HEA experienced severe mass loss during the 100 h immersion due to the high oxygen partial pressure and the galvanic corrosion effect. The corrosion products of FeCoNiCrAl HEA in the melt consist of Fe2O3, Cr2O3, FeCr2O4, and NaFeO2. After immersion for 100 h, an outer layer dominated by porous iron oxides and an inner more compact Cr-rich layer are formed. Furthermore, both of the oxide layers are gradually thickened with the extension of the corrosion time, and the process is manifested by the increased value of the oxide layer resistance Rox and charge transfer resistance Rt in the electrochemical impedance spectra. At the same time, compared with the Rt of 316L stainless steel, it can be seen that with the extension of corrosion time, the Rt of FeCoNiCrAl HEA is larger and shows better corrosion resistance in the same corrosive environment. In addition, FeCoNiCrAl HEA shows a higher corrosion potential and a lower corrosion current density than 316L in molten nitrates at 600°C.