bluuebunny/crossref_metadata_2025_split huggingface dataset:
Death from Failed Protection? An Evolutionary-Developmental Theory of Sudden Infant Death Syndrome
Authors: Renz-Polster Herbert , Blair Peter S. , Ball Helen L. , Jenni Oskar G. , De Bock Freia 
Published: July 2024

AbstractSudden infant death syndrome (SIDS) has been mainly described from a risk perspective, with a focus on endogenous, exogenous, and temporal risk factors that can interact to facilitate lethal outcomes. Here we discuss the limitations that this risk-based paradigm may have, using two of the major risk factors for SIDS, prone sleep position and bed-sharing, as examples. Based on a multipronged theoretical model encompassing evolutionary theory, developmental biology, and cultural mismatch theory, we conceptualize the vulnerability to SIDS as an imbalance between current physiologic-regulatory demands and current protective abilities on the part of the infant. From this understanding, SIDS appears as a developmental condition in which competencies relevant to self-protection fail to develop appropriately in the future victims. Since all of the protective resources in question are bound to emerge during normal infant development, we contend that SIDS may reflect an evolutionary mismatch situation—a constellation in which certain modern developmental influences may overextend the child’s adaptive (evolutionary) repertoire. We thus argue that SIDS may be better understood if the focus on risk factors is complemented by a deeper appreciation of the protective resources that human infants acquire during their normal development. We extensively analyze this evolutionary-developmental theory against the body of epidemiological and experimental evidence in SIDS research and thereby also address the as-of-yet unresolved question of why breastfeeding may be protective against SIDS.
Increased infiltration of M2-polarized tumour-associated macrophages is highly associated with advanced disease stage and high expression of PD-L1 in buccal mucosa carcinoma
Authors: Sun Hao-Jia , Zheng Zhui-Feng , Zhang Li-Jun , Fang Le , Fu Hua , Chen Shao-Yang , Feng Rong-Xiu , Liu Xiao-Yang , Tang Qing-Nan , Liu Xue-Wen 
Published: July 2024

Abstract
Objective
To assess the infiltration characteristics of tumour-associated macrophages (TAMs) in buccal mucosa carcinoma (BMC) and the correlation of these features with clinicopathological factors.

Materials and methods
Immunohistochemistry was used to detect the expression of TAM-related markers (CD68, CD163, CD206), CD8+ T cell markers, PD-L1, and epidermal growth factor receptor (EGFR) in 46 patients with mucosal cancer after radical surgery. In addition, the correlation between TAM infiltration and clinical characteristics, PD-L1 expression, and EGFR expression was analysed.

Results
A high infiltration level of M2-polarized (CD206+) TAMs and M2-polarized (CD163+) TAMs was more common in stage T3–T4, N+, III–IV patients than in other patient groups (P < 0.05). The infiltration degree of M2-polarized (CD68+) TAMs was positively correlated with the PD-L1 TPS (P = 0.0331). The infiltration level of M2-polarized (CD206+) TAMs was higher in the EGFR high expression group than in the EGFR low expression group (P = 0.040).

Conclusion
High infiltration of M2-polarized TAMs is highly associated with advanced disease stage and higher expression of PD-L1 and EGFR in BMCs, suggesting that M2-polarized TAMs infiltration can serve as a potential therapeutic target.
The Age of Datafeudalism: From Digital Panopticon to Synthetic Democracy
Authors: Saura García Carlos 
Published: July 2024

AbstractIn “Datafeudalism: The Domination of Modern Societies by Big Tech Companies” (Saura García in Phil Technol 37(3):1–18, 2024a) I analysed the concept of datafeudalism and its implications for the proper functioning of democracy. In this article, I put forward the hypothesis that big digital companies are exercising domination over the current social context and its different functional spheres, such as politics and democracy, and critique the negative implications that datafeudalism is having for the proper functioning of modern democratic systems. In this regard, Wörsdörfer (Phil Technol 37(3):1–5, 2024) has offered a critical commentary on the content in question. In particular, he focuses his discourse on the concept of the digital panopticon and its link with datafeudalism. The following replay present a reasoned response to these questions.
Unusual course of glyphosate-induced acute kidney injury: a case report of tubulointerstitial nephritis treated with steroids
Authors: Omote Daichi , Makino Shin-ichi , Okunaga Issei , Ishii Masayoshi , Tatsumoto Narihito , Aizawa Masashi , Asanuma Katsuhiko 
Published: July 2024

AbstractGlyphosate is a widely used herbicide that is generally considered safe; however, acute kidney injury (AKI) caused by glyphosate ingestion can be severe and require hemodialysis. We present a unique case of a 68-year-old Japanese man who developed AKI after accidental ingestion of glyphosate and required hemodialysis. Based on the clinical presentation and findings, the patient was diagnosed with renal AKI with severe tubulointerstitial damage. However, the precise pathogenesis of the tubulointerstitial damage remained unclear. An elevated beta-2 microglobulin level discovered by the urinalysis during admission raised the suspicion of tubulointerstitial nephritis caused by glyphosate. Gallium scintigraphy revealed accumulation in both kidneys. A renal biopsy revealed acute tubulointerstitial nephritis rather than acute tubular necrosis, which is commonly observed with glyphosate-induced renal injury. After initiating steroid therapy, his kidney function gradually improved and he was weaned from hemodialysis. This report is the first to describe glyphosate-induced acute tubulointerstitial nephritis that was successfully treated with immunosuppressive therapy. Furthermore, this report highlights the importance of steroid therapy for cases of persistent kidney injury after the discontinuation of agents associated with acute tubulointerstitial nephritis.
Radiation shielding and experimental characteristics of tincal waste added with obsidians
Authors: Aygun Z. , Astam A. , Aygun M. 
Published: July 2024

Abstract
The use of natural resources and waste products represents an effective way of addressing a pressing concern for the future of the global population. It is therefore crucial to evaluate wastes and natural materials as raw materials in many industries. The present study sought to investigate the radiation protection features and experimental characteristics of tincal waste added with obsidians from Eastern Turkey (Nemrut, Pasinler, Sarıkamış and Ikizdere regions). Fourier transform infrared spectrometry, X-ray diffraction, Scanning electron microscopy and Energy dispersive spectroscopy were used to have knowledge for morphological and structural properties of the samples. The X-ray diffraction analysis of the samples with higher obsidian content revealed an amorphous structure with a minor presence of crystalline phases. In contrast, the samples with a higher tincal waste content exhibited crystalline phases. Based on morphologic results, it can be said that obsidian samples exhibited relatively smooth and glassy surfaces, whereas tincal waste displayed a rough surface comprising randomly shaped small particles. In addition, radiation attenuating abilities of the tincal waste added with obsidians were determined by the calculation of tenth value layers, half value layers, mean free paths, mass attenuation coefficients, linear attenuation coefficients, fast neutron removal cross sections, effective atomic numbers and buildup factors using the newly produced Phy-X/PSD code. It is obtained that the samples show good radiation protection performances and the samples can be evaluated as better radiation shields for radiation applications especially in construction industry.
The Brain Salience Network at the Intersection of Pain and Substance use Disorders: Insights from Functional Neuroimaging Research
Authors: Li Xinyi , Kass Gabriel , Wiers Corinde E. , Shi Zhenhao 
Published: July 2024

Abstract
Purpose of Review
The brain’s salience network (SN), primarily comprising the anterior insula and anterior cingulate cortex, plays a key role in detecting salient stimuli and processing physical and socioemotional pain (e.g., social rejection). Mounting evidence underscores an altered SN in the etiology and maintenance of substance use disorders (SUDs). This paper aims to synthesize recent functional neuroimaging research emphasizing the SN’s involvement in SUDs and physical/socioemotional pain and explore the therapeutic prospects of targeting the SN for SUD treatment.

Recent Findings
The SN is repeatedly activated during the experience of both physical and socioemotional pain. Altered activation within the SN is associated with both SUDs and chronic pain conditions, characterized by aberrant activity and connectivity patterns as well as structural changes. Among individuals with SUDs, functional and structural alterations in the SN have been linked to abnormal salience attribution (e.g., heightened responsiveness to drug-related cues), impaired cognitive control (e.g., impulsivity), and compromised decision-making processes. The high prevalence of physical and socioemotional pain in the SUD population may further exacerbate SN alterations, thus contributing to hindered recovery progress and treatment failure. Interventions targeting the restoration of SN functioning, such as real-time functional MRI feedback, neuromodulation, and psychotherapeutic approaches, hold promise as innovative SUD treatments.

Summary
The review highlights the significance of alterations in the structure and function of the SN as potential mechanisms underlying the co-occurrence of SUDs and physical/socioemotional pain. Future work that integrates neuroimaging with other research methodologies will provide novel insights into the mechanistic role of the SN in SUDs and inform the development of next-generation treatment modalities.
Developing a multi-objective model for a multi-level supply chain of blood products under uncertainty and the global pandemic: a hybrid robust optimization approach
Authors: Esfandabadi Abolfazl Moghimi , Shishebori Davood , fakhrzad Mohammad-Bagher , Zare Hassan Khademi 
Published: July 2024

AbstractThe global COVID-19 pandemic has caused a substantial decrease in the blood supply and its products as a vital commodity. It has had adversely affected on the activities of blood organizations and facilities as well as public health. In this critical situation, the particular supply and blood demand products have affected certain sensitive managerial decisions. The purpose of the present study is to develop a multi-objective formulation for a multi-level supply chain of blood products under uncertainty and global pandemic conditions. The modeling is based on three objectives: minimizing the costs of the entire blood supply chain network, minimizing the pandemic virus transmission by donors in each of the blood donation centers, and maximizing the attractiveness of the blood donation centers in order to optimize the blood supply chain conditions and meet the needs of patients in the best possible way. Besides, since uncertainty is an integral part of supply chains, an efficient combination of scenarios, intervals and fuzzy robust optimization approaches is applied. As the results show, using robust approaches to deal with uncertain parameters can provide excellent conditions for efficient responses to those who demand blood products as well as pandemic patients who need the plasma of survivors.
Dynamics of urban heat island intensity in Lecce, Italy: seasonal, diurnal and heat wave influence
Authors: Pappaccogli Gianluca , Giangrande Francesco , Esposito Antonio , Donateo Antonio , Lionello Piero , Buccolieri Riccardo 
Published: July 2024

Abstract
This study investigates the impact of Heat Waves (HWs) on Urban Heat Island Intensity (UHII) in Lecce, a Mediterranean city in southern Italy. UHII was assessed using air temperature data from six weather stations over a four-year period (2020–2023). The results indicate that UHII is generally higher in winter and spring, with the ARPA (Environmental Protection Regional Agency) station consistently showing the highest values, particularly in summer, attributed to urban characteristics. The diurnal cycle of UHII reveals a peak in the early morning at most stations, followed by a decrease to near zero or slightly negative values during midday. Evening values then increase and persist throughout the night. Stations surrounded by green areas or located in suburban settings recorded the lowest UHII values. A total of eleven HWs occurred during the study period, with an average duration of 10 days. UHII was significantly more intense during HWs at all stations, with the greatest average observed at the ARPA station (2.60 °C) and the smallest at the LST (Liceo Scientifico Tabacchi) station (0.74 °C). These findings highlight the significant impact of HWs on UHI intensification in Lecce, especially in densely developed areas compared to suburban regions. This study emphasizes the importance of investigating UHII dynamics in Mediterranean cities to develop strategies for mitigating the Urban Heat Island (UHI) effect during extreme heat events.
Distribution of Power and Value Crucial for a Successful Circular Economy Transition
Authors: Tukker Arnold , Akkerman Renzo , Heideveld Antoine , Quist Jaco , Vrijhoef Ruben , Withagen Cees , Beumer Mark 
Published: July 2024

AbstractThe circular economy (CE) is heralded as reducing material use and emissions while providing more jobs and growth. We explored this narrative in a series of expert workshops, basing ourselves on theories, methods and findings from science fields such as global environmental input-output analysis, business modelling, industrial organisation, innovation sciences and transition studies. Our findings indicate that this dominant narrative suffers from at least three inconvenient truths. First, CE can lead to loss of GDP. Each doubling of product lifetimes will halve the related industrial production, while the required design changes may cost little. Second, the same mechanism can create losses of production jobs. This may not be compensated by extra maintenance, repair or refurbishing activities. Finally, ‘Product-as-a-Service’ business models supported by platform technologies are crucial for a CE transition. But by transforming consumers from owners to users, they lose independence and do not share in any value enhancement of assets (e.g., houses). As shown by Uber and AirBNB, platforms tend to concentrate power and value with providers, dramatically affecting the distribution of wealth. The real win-win potential of circularity is that the same societal welfare may be achieved with less production and fewer working hours, resulting in more leisure time. But it is perfectly possible that powerful platform providers capture most added value and channel that to their elite owners, at the expense of the purchasing power of ordinary people working fewer hours. Similar undesirable distributional effects may occur at the global scale: the service economies in the Global North may benefit from the additional repair and refurbishment activities, while economies in the Global South that are more oriented towards primary production will see these activities shrink. It is essential that CE research comes to grips with such effects. Furthermore, governance approaches mitigating unfair distribution of power and value are hence essential for a successful circularity transition.
Clinical applications of SPECT/CT in assessment of bone lesions in POEMS syndrome
Authors: Hou Yaqin , Zhao Zhilian , Zhang Haiqin , Guan Le , Li Ze , Song Tianbin , Lu Jie 
Published: July 2024

Abstract
Purpose
Retrospectively analyse the 99mTc-MDP SPECT whole-body bone scan in POEMS syndrome to explore its clinical value.

Methods
Twenty-four untreated patients with pathologically confirmed POEMS syndrome were included in the study. 24 of them underwent 99mTc-MDP SPECT whole-body bone scan, 24 underwent CT examination and 18 patients underwent X-ray examination in different parts. Features of bone lesions in 99mTc-MDP SPECT, and X-ray, CT were analysed. Three experienced radiologists read the images and gave diagnosed results for bone lesions.

Results
Of the 24 POEMS syndrome patients, three types of bone lesions were found: osteosclerotic lesions, osteolytic lesions and mixed lesions, of which the most common type was osteosclerotic. 54.16% (13/24) patients were found bone lesions by SPECT; 44.44% (8/18) patients underwent X-ray and 62.50% (15/24) patients underwent CT were detected bone lesions. We compared the difference of the X-ray, CT and SPECT scans of the bone lesions by chi-square and found that there was no difference (P = 0.51) in detection of bone lesions among the three methods.

Conclusion
99mTc-MDP SPECT wholebody bone scan also useful in evaluating patients with suspected POEMS syndrome. We can use it as a supplement examination of the CT in the confirmation of one minor diagnostic criterion for POEMS syndrome: bone lesions.
Land-use suitability assessment for urban development using Multi-Criteria Decision-Making Analysis in the Himalayan districts of Shimla, Nainital, and Darjeeling, India
Authors: Suthar Neeraj , Das Dip , Mallik Jyotirmoy 
Published: July 2024

AbstractAfter India gained independence in 1947, notable advancements in healthcare and socio-economic sectors resulted in a remarkable population surge, consequently driving substantial expansion in built-up areas throughout the country. The consequences of the rapid and unplanned expansion are adverse in the Himalayas where earthquake, landslides, flash floods are frequent. The already established hill stations saw a rapid surge in tourism and subsequent urbanization. This study delves into assessing the urban suitability of such hill stations namely Nainital, Shimla, and Darjeeling. The surge in tourism led to alarming population growth with haphazard urbanization which is often severely affected by growing natural hazards. The aim of this study is to assess the urbanization suitability of the regions based on multiple factors that affects the choice of suitable place for urban growth. We employed the GIS based Multi-Criteria Decision-Making Approach (MCDMA) considering geological, socio-economical, ecological, and prohibitive factors using the Analytical Hierarchy Process (AHP) method. The obtained land-use suitability maps for urbanization show that in Nainital the most suitable area for urbanization is the foothills of the Himalayas whereas in Shimla it is around the central and southern part. The northern part and the eastern boundary of Darjeeling are the most suitable area for urbanization. Upon comparing the already existing built-up areas with the AHP derived site suitability results we found that the Darjeeling district is most vulnerable as almost half of the built-up area (49%) lies within a very low to moderate suitable zone. Our findings show that Darjeeling has the highest amount of suitable land for urbanization as the bare ground in the region is not suitable for agriculture. Interestingly, the farmlands in Nainital show highest suitability when urbanization is considered. This brings out a serious problem in urbanization trend and it is observed throughout the world. Thus, more careful research is needed ensuring proper land use and food security for the growing population. This study lays a foundational understanding of challenges associated to urbanization in a tectonically active mountain range.
A systematic literature review on the relationship between education and gender ideology
Authors: Hossain Delwar , Islam Rabiul 
Published: July 2024

AbstractThe nexus between education and gender ideology is a debated issue worldwide, including in Bangladesh. This study aims to understand the educational influences on gender ideology. Authors have reviewed electronic databases, including Science Direct, Scopus, Google Scholar, and Web of Science, to collect published material from 2014 to 2023. Based on the research objectives, 20 studies were reviewed among 1438. The study found various theories and models, such as human capital theory, gender role theory, patriarchy theory, intersectionality theory, empowerment theory, gender identity theory, behavioral theory, and socialization and reproduction model, exploring the link between education and gender ideologies. This study also found that the quantitative methods dominate the research landscape, while qualitative and mixed-method approaches offer profound insights into the contextual factors that influence gender ideology. Additionally, findings from the studies indicate that education is positively associated with liberal gender ideology. This study suggests an insight for future researchers on the educational impact of gender ideology, its theoretical frameworks, methodologies, and the current knowledge gap.
High Arctic Vegetation Communities With a Thick Moss Layer Slow Active Layer Thaw
Authors: Schuuring Sil , Halvorsen Rune , Bronken Eidesen Pernille , Niittynen Pekka , Kemppinen Julia , Lang Simone I. 
Published: July 2024

AbstractSvalbards permafrost is thawing as a direct consequence of climate change. In the Low Arctic, vegetation has been shown to slow down and reduce the active layer thaw, yet it is unknown whether this also applies to High Arctic regions like Svalbard where vegetation is smaller, sparser, and thus likely less able to insulate the soil. Therefore, it remains unknown which components of High Arctic vegetation impact active layer thaw and at which temporal scale this insulation could be effective. Such knowledge is necessary to predict and understand future changes in active layer in a changing Arctic. In this study we used frost tubes placed in study grids located in Svalbard with known vegetation composition, to monitor the progression of active layer thaw and analyze the relationship between vegetation composition, vegetation structure and snow conditions, and active layer thaw early in summer. We found that moss thickness, shrub and forb height, and vascular vegetation cover delayed soil thaw immediately after snow melt. These insulating effects attenuated as thaw progressed, until no effect on thaw depth was present after 8 weeks. High Arctic mosses are expected to decline due to climate change, which could lead to a loss in insulating capacity, potentially accelerating early summer active layer thaw. This may have important repercussions for a wide range of ecosystem functions such as plant phenology and decomposition processes.