bluuebunny/crossref_metadata_2025_split huggingface dataset:
Emotional food design: From designing food products to designing food systems
Authors: Wrigley Cara , Ramsey Rebecca 
Published: October 2015

Abstract
Contemporary food systems promote the consumption of highly processed foods of limited nutrition, contributing to overweight and obesity, diet-related disease and significant financial burden on healthcare systems. In part, this has resulted from highly successful design, development and marketing strategies for processed foods. The successful application of such strategies to healthy food options, and the services and business plans that accompany them, could assist in enhancing health and alleviating burden on health care systems.
Product designers have long been aware of the importance of intertwining emotional experiences with new products. However, a lack of theoretical precision exists for applying emotional design beyond food products, to the food systems, services and business models that drive them. This article explores emotional design within the context of food and food systems and proposes a new concept – Emotional Food Design (EFD), through which emotional design is integrated across levels of a food system. EFD complements the dominating deductive view of food systems research with an abductive iterative design approach contextualized within the creation of new food products, services and business models and their associated emotional attachments. This paper concludes by outlining what EFD can offer to reorient food systems to successfully promote healthy eating.
Only half the story: Radio drama, online audio and transmedia storytelling
Authors: Dann Lance 
Published: October 2015

Abstract
Online audio drama creates the potential not just for new forms and patterns of listening (on-demand and audience-controlled) or for revised methods of plot structuring (with series stacking allowing for the use of extended narrative arcs) but of a complete recreation of the listening experience as part of an act of transmedia storytelling – one in which the narrative spins out of the wireless and overlays the ‘lived’ experience of the listener. This article will discuss the opportunities that have been opened up for writers and producers of radio drama through the development of online and downloadable audio. It will discuss the use of both social media tools and diverse media platforms in a construction of story in which the membrane between the real and fictive has become permeable. It will focus on the author’s ongoing work on The Flickerman, a piece of applied creative research that began as an attempt to explore the possibilities offered to writers by working outside conventional radio networks, and has developed into a piece of as-live, collaborative, open-source storytelling.
‘I know exactly who they are’: Radio presenters’ conceptions of audience
Authors: Wolfenden Helen 
Published: October 2015

Abstract
Since Horton and Wohl’s recognition of the para-social relationship, there has been an interest in understanding the relationship between presenters and audiences beyond commodification models. But while the relationship has long been named, little is understood about the process from ‘inside’ the presenter experience: what audiences mean to presenters, how the relationship is constructed and becomes real in the absence of face-to-face contact when, for the most part, the presenter can only know the audience as an abstraction or a projection. This article will explore the way Australian Broadcasting Corporation (ABC) talk radio presenters construct their audience as a dialogue partner, and the way that the on-air self is managed, in line with the corporate expectations of their employer, to achieve the appropriate symbolic indicators of friendship, sympathy, companionship, disclosure and intimacy. The findings are based on interviews with leading ABC radio presenters.
Uniaxial Dynamic Mechanical Properties Of Tunnel Lining Concrete Under Moderate-Low Strain Rate After High Temperature
Authors: Xiong L. X. 
Published: October 2015

AbstractTo investigate the mechanical properties of tunnel lining concrete under different moderate-low strain rates after high temperatures, uniaxial compression tests in association with ultrasonic tests were performed. Test results show that the ultrasonic wave velocity and mass loss of concrete specimen begin to sharply drop after high temperatures of 600 °C and 400 °C, respectively, at the strain rates of 10-5s-1 to 10-2s-1. The compressive strength and elastic modulus of specimen increase with increasing strain rate after the same temperature, but it is difficult to obtain an evident change law of peak strain with increasing strain rate. The compressive strength of concrete specimen decreases first, and then increases, but decreases again in the temperatures ranging from room temperature to 800 °C at the strain rates of 10-5s-1 to 10-2s-1. It can be observed that the strain-rate sensitivity of compressive strength of specimen increases with increasing temperature. In addition, the peak strain also increases but the elastic modulus decreases substantially with increasing temperature under the same strain rate.
Probabilistic Analysis Of A Space Truss By Means Of A Multidimensional Variable Description
Authors: Sorn P. , Górski J. , Przewłócki J. 
Published: October 2015

AbstractProbabilistic analysis of a space truss is presented in the paper. Reliability of such a structure is sensitive to geometrical and material imperfections. The objective of this paper is to present a variant of the point estimate method (PEM) to determine mean values and standard deviations of limit loads of engineering structures. The main advantage presented by this method is the small number of sample calculations required to obtain estimators of investigated parameters. Thus the method is straightforward, requiring only preliminaries of probability theory. This approach is illustrated by limit state analysis of a space truss, considering geometric and material imperfections. The calculations were performed for different random models, so the influence of random parameters on the limit load of the truss can be determined. A realistic snow load was imposed.
Synthesis of pyranopyrazolo N-glycoside and pyrazolopyranopyrimidine C-glycoside derivatives as promising antitumor and antimicrobial agents
Authors: Hafez Hend N. , El-Gazzar Abdel-Rhman B. A. 
Published: October 2015

Abstract
As a part of systematic investigation of the synthesis and biological activities of pyrazole analogues linked to various heterocyclic systems, a new series of pyrazolo-N-glycoside derivatives, pyrazolopyranopyrimidine and C-glycoside of pyrazolopyranotriazolo-pyrimidine derivatives was synthesized through the reaction of the key intermediate 6-amino-3-methyl-4-(substituted-phenyl)-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile (3a,b) with different reagents. Structures of the newly synthesized compounds were elucidated by elemental microanalysis and spectroscopic methods. The compounds were subjected to in vitro antitumor evaluation using the MTT assay. N-(β-D-ribofuranosyl)- and N-(β-D-xylofuranosyl)-6{[(1E)-4-chlorophenyl)-methylene] amino}4-(4-florophenyl)-3-methyl-1,4-dihydropyrano[2,3-c]-pyrazole-5-carbonitrile (6a,b) were the most active compounds against three human cancer cell lines. Also, most of the newly synthesized compounds exhibited high activity towards Gram-negative and Gram-positive bacteria. Compound 6a exhibited excellent activity towards bacteria compared to ofloxacine as the reference drug.
Development of a high-throughput screening system for identification of novel reagents regulating DNA damage in human dermal fibroblasts
Authors: Bae Seunghee , An In-Sook , An Sungkwan 
Published: October 2015

Abstract
Ultraviolet (UV) radiation is a major inducer of skin aging and accumulated exposure to UV radiation increases DNA damage in skin cells, including dermal fibroblasts. In the present study, we developed a novel DNA repair regulating material discovery (DREAM) system for the high-throughput screening and identification of putative materials regulating DNA repair in skin cells. First, we established a modified lentivirus expressing the luciferase and hypoxanthine phosphoribosyl transferase (HPRT) genes. Then, human dermal fibroblast WS-1 cells were infected with the modified lentivirus and selected with puromycin to establish cells that stably expressed luciferase and HPRT (DREAM-F cells). The first step in the DREAM protocol was a 96-well-based screening procedure, involving the analysis of cell viability and luciferase activity after pretreatment of DREAM-F cells with reagents of interest and post-treatment with UVB radiation, and vice versa. In the second step, we validated certain effective reagents identified in the first step by analyzing the cell cycle, evaluating cell death, and performing HPRT-DNA sequencing in DREAM-F cells treated with these reagents and UVB. This DREAM system is scalable and forms a time-saving high-throughput screening system for identifying novel anti-photoaging reagents regulating DNA damage in dermal fibroblasts.
Curcumin phytosomal softgel formulation: Development, optimization and physicochemical characterization
Authors: Allam Ahmed N. , Komeil Ibrahim A. , Abdallah Ossama Y. 
Published: October 2015

Abstract
Curcumin, a naturally occurring lipophilic molecule can exert multiple and diverse bioactivities. However, its limited aqueous solubility and extensive presystemic metabolism restrict its bioavailability. Curcumin phytosomes were prepared by a simple solvent evaporation method where free flowing powder was obtained in addition to a newly developed semisolid formulation to increase curcumin content in softgels. Phytosomal powder was characterized in terms of drug content and zeta potential. Thirteen different softgel formulations were developed using oils such as Miglyol 812, castor oil and oleic acid, a hydrophilic vehicle such as PEG 400 and bioactive surfactants such as Cremophor EL and KLS P 124. Selected formulations were characterized in terms of curcumin in vitro dissolution. TEM analysis revealed good stability and a spherical, self-closed structure of curcumin phytosomes in complex formulations. Stability studies of chosen formulations prepared using the hydrophilic vehicle revealed a stable curcumin dissolution pattern. In contrast, a dramatic decrease in curcumin dissolution was observed in case of phytosomes formulated in oily vehicles.
Anti-breast cancer activity of some novel quinoline derivatives
Authors: Ghorab Mostafa M. , Alsaid Mansour S. 
Published: October 2015

Abstract
To discover new bioactive lead compounds for medicinal purposes, 2-cyano-3-(4-substituted)-N-(quinolin-3-yl) acrylamide derivatives 2–24, chromenes 25, 26 and benzochromenes 27, 28 were synthesized. The structures of the newly synthesized compounds were confirmed by elemental analyses, IR, 1H NMR and 13C NMR spectroscopies. In addition, the structure of compound 1 was confirmed through X-ray crystallography. All the newly synthesized compounds were evaluated for their cytotoxic activity against the breast cancer cell line MCF7. The corresponding 2-cyano-3-(4-hydroxy-3-methoxyphenyl)-N-(quinolin-3-yl) acrylamide (15), 3-oxo-N-(quinolin-3-yl)-3H-benzol[f] chromene-2-carboxamide (27), 2-cyano-3-(4-fluorophenyl-N-(quinolin-3-yl) acrylamide (7), 2-cyano-5-(4-(dimethyl-amino) phenyl)-N-(quinolin-3-yl) penta-2,4-dienamide (19) exhibited higher activity compared to doxorubicin (with IC
50 value of 47.9 μmol L−1) as a reference drug, with IC
50 values of 29.8, 39.0, 40.0, 40.4 μmol L−1, resp. Also, quinoline acrylamides containing 2,3,4-trimethoxyphenyl 17, 2-chlorophenyl 10, benzo[d][1,3]dioxol 12, 2-methoxynaphthalen 22, 2,4-dichlorophenyl 18 and quinoline carrying a chromene-3-carboxamide moiety 25 were nearly as active as doxorubicin, while quinoline acrylamides incorporating unsubstituted phenyl 2, p-tolyl 3, 2,4-dienamide 8, 3-nitrophenyl 13, 4-nitrophenyl 14, 3,4-dimethoxyphenyl 16 and chromene 26 exhibited a moderate activity. In addition, quinoline with acetamide 1, 4-hydroxyphenyl 4, 4-dimethylaminophenyl 9, 4-chlorophenyl 11, 3-bromophenyl 20, 4-bromophenyl 21 and 3-thienyl moiety 24 showed less activity than doxorubicin. On the other hand, quinoline having 2-methoxyphenyl 5, 4-methoxyphenyl 6, 4-metho xynaphthalene 23 and chromene-2-carboxamide 28 showed no activity.
A General Fixed Point Theorem For Implicit Cyclic Multi-Valued Contraction Mappings
Authors: Popa Valeriu 
Published: October 2015

Abstract
In this paper, a general fixed point theorem for cyclic multi-valued mappings satisfying an implicit relation from [19] different from implicit relations used in [13] and [23], generalizing some results from [22], [15], [13], [14], [16], [10] and from other papers, is proved.
The analysis of parameters of the cryogenic oxygen unit cooperating with power plant to realize oxy-fuel combustion
Authors: Hnydiuk-Stefan Anna , Składzień Jan 
Published: October 2015

Abstract
The paper examines from the thermodynamic point of view operation of coal fired power unit cooperating with the cryogenic oxygen unit, with a particular emphasis on the characteristic performance parameters of the oxygen unit. The relatively high purity technical oxygen produced in the oxygen unit is then used as the oxidant in the fluidized bed boiler of the modern coal fired power unit with electric power output of approximately 460 MW. The analyzed oxygen unit has a classical two-column structure with an expansion turbine (turboexpander), which allows the use of relatively low pressure initially compressed air. Multivariant calculations were performed, the main result being the loss of power and efficiency of the unit due to the need to ensure adequate driving power to the compressor system of the oxygen generating plant.
Mycoplasma bovis infections and co-infections with other Mycoplasma spp. with different clinical manifestations in affected cattle herds in eastern region of Poland
Authors: Szacawa Ewelina , Niemczuk Krzysztof , Dudek Katarzyna , Bednarek Dariusz , Rosales Ruben , Ayling Roger 
Published: October 2015

Abstract
The aim of the study was to evaluate the presence of Mycoplasma bovis infection and co-infections with other Mycoplasma spp. infections in cattle. The tested population was one in the eastern region of Poland containing 66 dairy cows and 23 calves showing different clinical signs and suffering from pneumonia, mastitis, and arthritis. The incidence of M. bovis in co-infections with other Mycoplasma spp. was examined using serological traditional mycoplasma culture methods, and the molecular methods - PCR and polymerase chain reaction/denaturing gradient gel electrophoresis (PCR/DGGE). The PCR/DGGE method for detecting Mycoplasma spp. in cattle was used for the first time in Poland. The seroprevalence of M. bovis in the affected cattle herds in the eastern region of Poland was 47.8% in calves and 19.7% in dairy cows. The direct detection and identification of M. bovis from nasopharyngeal swabs by PCR revealed that 56.5% of calves were positive, but all of the dairy cows were negative. The PCR/DGGE identified eight (34.8%) instances of M. arginini and eight (26.1%) instances of M. bovirhinis co-infecting with M. bovis in ten calves. The seroprevalence of M. bovis in the tested population was 33.7%. Any future attempts to control mycoplasma infections require an insight into the current epidemiological situation of M. bovis infection and its relationship to other mycoplasmas in causing clinical disease in cattle. Using these diagnostic methods we have demonstrated that mycoplasmal infections are often caused by multiple species of Mycoplasma and not just the primary M. bovis pathogen.
First report of the giant liver fluke (Fascioloides magna) infection in farmed fallow deer (Dama dama) in Poland – pathomorphological changes and molecular identification
Authors: Karamon Jacek , Larska Magdalena , Jasik Agnieszka , Sell Bartosz 
Published: October 2015

Abstract
A 3-year-old female fallow deer was subjected to the necropsy and virological testing, due to a suspected infectious disease in the herd of farmed deer in the Southeastern region of Poland. The animal was found negative for the presence of BVDV, BoHV-1, BTV, and EHDV antibodies and BVDV antigen. The toxicological examination did not reveal any coccidiostats, mycotoxins, rodenticides, carbamate pesticides, and organophosphorus pesticides. The flukes found during postmortem examination were first characterised microscopically as Fascioloides magna and later their identity was confirmed by PCR and sequencing. The autopsy revealed lesions characteristic for F. magna infection, including different size cystic spaces in the liver, filled with brownish mucous fluid and flukes, and black pigment covering the surface of parietal and visceral peritoneum with the highest concentrations localised next to the liver. The changes observed in the liver tissue were typical of liver cirrhosis. The results demonstrated that in Poland, where the cervid farming is developing dynamically, the problem of fascioloidosis is present and may probably exert a significantly negative influence on the productivity of such farms if no antiparasitic treatment is performed.
Impact of low-concentrated acidic electrolysed water obtained by membrane electrolysis on the decontamination of meat microbiota
Authors: Brychcy Ewa , Jarmoluk Andrzej , Marycz Krzysztof 
Published: October 2015

Abstract
The influence of acidic electrolysed water (AEW) treatment on inactivation of pure bacterial cultures inoculated onto the surface of agarised media and surface microbiota of pork meat were examined. Low-concentrated AEW (low concentration of sodium chloride and low current electrolysis) was generated by electrolysis (5 or 10 min) of 0.001% or 0.01% NaCl solution. The number of viable microorganisms was determined using a plate count method. The effect of AEW on bacterial cell morphology were investigated using scanning electron microscopy (SEM). After treatment with AEW, a significant, about 3.00 log reduction of Pseudomonas fluorescens, Yersinia enterocolitica, Escherichia coli, Staphylococcus aureus, Bacillus subtilis, Listeria monocytogenes, and Micrococcus luteus populations was observed. In the AEW treatment of pork, the highest reduction of total number of microorganisms (2.1 log reduction), yeast and moulds (2.5-2.6 log reduction), and psychrotrophs (more than 1 log reduction) was observed after spraying with 0.001% NaCl subjected to 10 min electrolysis. SEM revealed disruption and lysis of E. coli and S. aureus cells treated with AEW, suggesting a bactericidal effect. Higher available chlorine concentration (0.37-8.45 mg/L), redox potential (863.1-1049.8 mV), and lower pH (2.73-3.70) had an influence on the shape of bacteria and the number of breaks in the bacterial membrane.
Percentage of CD4+, CD8+, and CD25+ T lymphocytes in peripheral blood of pigs in the course of experimental burns and necrectomy
Authors: Aleksiewicz Roman , Kostro Krzysztof , Kostrzewski Marek , Lisiecka Beata , Bojarski Marcin , Mucha Paweł Adam 
Published: October 2015

Abstract
The aim of the study was the evaluation of changes in the percentage profile of CD4+, CD8+, and CD25+ T lymphocytes, and their predictive value with respect to the course of experimental skin burns and early necrectomy in pigs. Thirty Large White Landrace pigs of both genders, weighing 50 kg (±2 kg), were used. Burns to their skin were performed with the use of a computer-controlled heating plate, applied to the animal’s body and heated to 2000°C, using 2.5 kg pressure for 10 s. It produced a burn of 30% (±2%) of body surface with a range of damage between II b° and III°. In animals of each experimental group fascial necrectomy was performed, according to the testing module. Blood from experimental and non-treated control animals was collected from the external jugular vein before the beginning of the experiment (hour 0) and at 12, 24, 36, 48, 60, 72, 84, 96, 108, 120, 132, 144, 156, 168, and 180 h of the experiment. An immune response profile was evaluated using flow cytometry analysis of the level and expression dynamics of CD4+, CD8+, and CD25+ particles on the surface of T lymphocytes. The study demonstrated that experimentally-induced burns in pigs caused cell-mediated immune response reflected in the changes in the percentage of CD4+, CD8+, and CD25+ T lymphocytes, and that early necrectomy in burnt pigs acted in a protective manner for the organism, based on the immunological index values. The study also proved that the dynamics of cell-mediated immunological response intensification determined on the basis of the percentage of CD4+, CD8+, and CD25+ T lymphocytes is conditioned by the size of the burnt surface and the time of necrectomy procedure.
Approaches to assessment in CLIL classrooms: Two case studies
Authors: O’Dwyer Fergus , de Boer Mark 
Published: October 2015

AbstractThis article presents two case studies that show how learner involvement and collaboration in assessment are valid pedagogic tools to encourage learner reflection and engagement, particularly where a very traditional approach to language learning is the norm. The authors, who teach in universities in Japan, discuss different but related approaches to assessment in CLIL (Content and Language Integrated Learning) classrooms. The first case study describes how assessment in the classrooms in focus requires more engagement on the part of learners as they must work things out for themselves. Collaborating with classmates, which entails discussing assessment decisions, can foster language development. If learners engage in informal discussion about their learning performance, they can review previous learning, affirm progress, and make suggestions about future learning goals and how to improve their learning outcomes. In the authors’ view these processes help learners to develop self-regulation and self-efficacy. The second case study involves students developing collaboration skills during project work in which they are also involved in the assessment process. They give slide and poster presentations, write reports, and analyze scientific information while collaborating with their classmates. During this process they are also responsible for self- and peer-assessment. As a result of their collaboration they acquire language, but they also develop the ability to collaborate further. The article concludes by briefly discussing learner involvement and collaboration, and the central role that feedback practices can play in learning.
Integrated learner support through language advising: Initial experiences and considerations at Padova University Language Centre
Authors: Bisset Mariana , Gödeke Barbara 
Published: October 2015

AbstractThe Language Centre at the University of Padova provides language courses for students of all disciplines and with a wide range of needs. Over the years, the number of students having to deal with a language requirement has increased exponentially, while the teaching personnel and general resources have struggled to keep up. Catering to all of the various needs, expectations, time commitments and background experience of the students poses quite a challenge. Fostering autonomy in learners by helping them to develop skills related to self-management, self-monitoring and self-assessment (