bluuebunny/crossref_metadata_2025_split huggingface dataset:
One More Story: Racial Relations and Stereotypes in Brazilian Literature
Authors: da Silva Paulo V. Baptista 
Published: August 2014

AbstractThe article deals with race relations in Brazil, analyzing how adult and children’s literature in Brazil has worked to maintain and update the “Prospero complex”. The article is guided by the hypothesis that the main challenge is to mover narratives, literature and textbooks to go beyond the homogeneity of a single story based on white as representative “natural” of the human species that discursively places the “other” as “deviant”; from the hegemony of the white hierarchy for plural discourses. In Brazilian literature racial hierarchies are largely profuse and profound. The analysis of “the Negro as an object” indicates the presence of some striking black characters as the few characters with a tendency to subordination and inferiority. The alternatives are linked to the “black literature” that demonstrates richness and strength but at the same time this literature is maintained as “marginal.” In children’s literature the process is very similar, observing continuous forms of hierarchy of whites as superior and blacks as inferior. The article discusses the production of alternatives and other new literary discourses and the need for teacher training.
Treatment of Esophageal Perforation: A Single-Center Expertise
Authors: Troja A. , Käse P. , El-Sourani N. , Miftode S. , Raab H. R. , Antolovic D. 
Published: August 2014

Background and Aims: Esophageal perforation is a rare diagnosis, which is associated with a high morbidity and mortality. There is only small scientific background regarding the best choice of treatment. Parameters indicating a good clinical outcome seem to be localization, depth of the defect, pre-existing risk factors, and time interval between the event and start of treatment. Material and Methods: We evaluate retrospective data from 39 patients who were treated with a esophageal perforation in our hospital between 2004 and 2012. Results and Conclusions: Our collected data agree with the available published literature. Endoscopic treatment seems to be favorable in early diagnosis.
Rates and Determinants of Return to Play After Anterior Cruciate Ligament Reconstruction in NCAA Division 1 College Football Athletes
Authors: Daruwalla Jimmy H. , Greis Patrick E. , Hancock Robert ,   ASP Collaborative Group, Xerogeanes John W. , McCarty Eric C. , Reynolds Kirk , Rueda Miguel , Moorman Claude T. , Johnson Darren , Dragoo Jason , Bartlinski Steve , Spang Jeffrey , Creighton R. Alex , Taft Tim , Trulock Scott , Halverson Doug , Hatch George F. Rick , Merriman Jarrad , Romano Russ , Spindler Kurt , Bossung Thomas , Diduch David , Pugh Kelli , Tingstad Edwin M. , Kaplan Lee , Gombosh Michael 
Published: August 2014

Background: For competitive athletes, return to play (RTP) and return to preinjury levels of performance after anterior cruciate ligament (ACL) reconstruction are the main goals of surgery. Although outcomes of ACL surgery are well studied, details on factors influencing RTP in elite college football players have not been evaluated thoroughly. Purpose: To determine the rate of RTP following ACL surgery among National Collegiate Athletic Association (NCAA) Division 1 collegiate football athletes and to examine variables that may affect these rates. The hypothesis was that the RTP rate in this cohort will be influenced by factors reflecting skill and accomplishment; that is, athletes higher on the depth chart, those on scholarship, and those later in their careers will have higher RTP rates. It was also predicted that graft type and concomitant procedures may have an effect on RTP rates. Study Design: Case series; Level of evidence, 4. Methods: Using athlete- and surgery-specific data from participating institutions in 3 major Division 1 college football conferences, information on athletes who had ACL reconstruction from 2004 through 2010 was collected. Statistical analyses were performed to determine the RTP rate as a function of the variables, such as depth chart position, in the data collected. Results: Of the 184-player cohort, 82% of the athletes, including 94% of starters, were able to RTP. Rates were greater among athletes higher on the depth chart ( P = .004) and on scholarship ( P = .008). Year of eligibility also affected RTP rates ( P = .047), which increased from the redshirt and freshman year to the sophomore and junior years, but then decreased slightly into the senior and fifth-year senior seasons. The use of an autograft versus allograft was associated with increased RTP ( P = .045). There was no significant difference ( P = .18) between players who underwent an isolated ACL reconstruction versus those who underwent additional procedures. Conclusion: More than 80% of football players at the Division 1 level were able to RTP following ACL reconstruction. Factors representative of a player’s skill were associated with higher rates of RTP. Surgery-specific variables, in general, had no effect on RTP, except for the use of autograft, which was associated with a greater RTP rate.
GEM2005 trial update comparing VMP/VTP as induction in elderly multiple myeloma patients: do we still need alkylators?
Authors: Mateos María-Victoria , Oriol Albert , Martínez-López Joaquín , Teruel Ana-Isabel , López de la Guía Ana , López Javier , Bengoechea Enrique , Pérez Montserrat , Martínez Rafael , Palomera Luis , de Arriba Felipe , González Yolanda , Hernández José Mariano , Granell Miquel , Bello José-Luis , Bargay Joan , Peñalver Francisco-Javier , Martín-Mateos María-Luisa , Paiva Bruno , Montalbán María-Angeles , Bladé Joan , Lahuerta Juan-Jose , San-Miguel Jesús F. 
Published: August 2014

Key Points
Melphalan, in combination with bortezomib, should be maintained as one of the standards of care for the treatment of elderly MM patients. Complete response and particularly flow complete response should be an important goal in the treatment of elderly myeloma patients.
Nocturnal intermittent hypoxia predicts prevalent hypertension in the European Sleep Apnoea Database cohort study
Authors: Tkacova Ruzena , McNicholas Walter T. , Javorsky Martin , Fietze Ingo , Sliwinski Pawel , Parati Gianfranco , Grote Ludger , Hedner Jan 
Published: August 2014

Systemic hypertension is associated with obstructive sleep apnoea syndrome (OSAS) but the pathophysiological mechanisms are incompletely understood. A collaborative European network of 24 sleep centres established a European Sleep Apnoea Database to evaluate cardiovascular morbidity associated with OSAS.11 911 adults referred with suspected OSAS between March 2007 and September 2013 underwent overnight sleep studies, either cardiorespiratory polygraphy or polysomnography. We compared the predictive value of the apnoea–hypopnoea index (AHI) and 4% oxygen desaturation index (ODI) for prevalent hypertension, adjusting for relevant covariates including age, smoking, obesity, dyslipidaemia and diabetes.Among patients (70% male, mean±sdage 52±12 years), 78% had AHI >5 events·h−1and 41% systemic hypertension. Both AHI and ODI independently related to prevalent hypertension after adjustment for relevant covariates (p<0.0001 for linear trend across quartiles (Q) of severity for both variables). However, in multiple regression analysis with both ODI and AHI in the model, ODI was, whereas AHI was not, independently associated with prevalent hypertension: odds ratios (95% CI) for Q4versusQ1 regarding ODI were 2.01 (1.61–2.51) and regarding AHI were 0.92 (0.74–1.15) (p<0.0001 and p=0.3054, respectively).This cross sectional study suggests that chronic intermittent hypoxia plays an important role in OSAS-related hypertension.
Th22 cells are expanded in multiple sclerosis and are resistant to IFN-β
Authors: Rolla Simona , Bardina Valentina , De Mercanti Stefania , Quaglino Pietro , De Palma Raffaele , Gned Dario , Brusa Davide , Durelli Luca , Novelli Francesco , Clerico Marinella 
Published: August 2014

AbstractTh1 and Th17 cells have been considered as effectors in mouse EAE and in the human counterpart, MS. Recently, IL-22, a Th17-related, proinflammatory cytokine, has been associated with a new Th cell subset, defined as Th22, involved in chronic inflammatory conditions, such as psoriasis; the role of IL-22 in MS has not yet been elucidated. Here, we report that similar to Th17 cells, the number of Th22 cells increased in the PB and the CSF of RR MS patients, especially during the active phases of the disease. However, as opposed to Th17 cells, the expansion of Th22 cells occurred before the active phases of the disease. Th22 cells were found to be specific for the autoantigen MBP and also expressed high levels of CCR6 and T-bet, as for Th17 cells, indicating that Th22 self-reactive cells could have CNS-homing properties and be pathogenic in active RRMS patients. Conversely to Th17 cells, Th22 cells displayed lower levels of IFNAR1 and were insensitive to IFN-β inhibition. These data suggest that expansion of Th22 cells in MS could be one of the factors that critically influence resistance to IFN-β therapy.
Clinical and social factors associated with attention-deficit hyperactivity disorder medication use: population-based longitudinal study
Authors: Galéra Cédric , Pingault Jean-Baptiste , Michel Grégory , Bouvard Manuel-Pierre , Melchior Maria , Falissard Bruno , Boivin Michel , Tremblay Richard E. , Côté Sylvana M. 
Published: August 2014

BackgroundThe impact of longitudinal psychiatric comorbidity, parenting and social characteristics on attention-deficit hyperactivity disorder (ADHD) medication use is still poorly understood.AimsTo assess the baseline and longitudinal influences of behavioural and environmental factors on ADHD medication use.MethodSurvival regressions with time-dependent covariates were used to model data from a population-based longitudinal birth cohort. The sample (n= 1920) was assessed from age 5 months to 10 years. Measures of children's psychiatric symptoms, parenting practices and social characteristics available at baseline and during follow-up were used to identify individual and family-level features associated with subsequent use of ADHD medication.ResultsUse of ADHD medication ranged from 0.2 to 8.6% between ages 3.5 to 10 years. Hyperactivity–inattention was the strongest predictor of medication use (hazard ratio (HR) = 2.75, 95% CI 2.35–3.22). Among all social variables examined, low maternal education increased the likelihood of medication use (HR = 2.09, 95% CI 1.38–3.18) whereas immigrant status lowered this likelihood (HR = 0.40, 95% CI 0.17–0.92).ConclusionsBeyond ADHD symptoms, the likelihood of receiving ADHD medication is predicted by social variables and not by psychiatric comorbidity or by parenting. This emphasises the need to improve global interventions by offering the same therapeutic opportunities (including medication) as those received by the rest of the population to some subgroups (i.e. immigrants) and by diminishing possible unnecessary prescriptions.
High paracellular nutrient absorption in intact bats is associated with high paracellular permeability in perfused intestinal segments
Authors: Brun Antonio , Price Edwin R. , Gontero-Fourcade Manuel N. , Fernández-Marinone Guido , Cruz-Neto Ariovaldo P. , Karasov William H. , Caviedes-Vidal Enrique 
Published: August 2014

Abstract
Water-soluble nutrients are absorbed by the small intestine via transcellular and paracellular mechanisms. Based on a few previous studies, the capacity for paracellular nutrient absorption seems greater in ﬂying mammals than in nonﬂying mammals, but there has been little investigation of the mechanisms driving this difference. Therefore, we studied three species each of bats (Artibeus lituratus, Sturnira lilium, Carollia perspicillata) and nonflying mammals (Akodon montensis, Mus musculus, Rattus norvegicus). Using standard pharmacokinetic techniques in intact animals, we confirmed the greater paracellular nutrient absorption in the fliers, comparing one species in each group. Then we conducted in situ intestinal perfusions on individuals of all species. In both approaches, we measured the absorption of 3OMD-glucose, a nonmetabolizable glucose analog absorbed paracellular and transcellularly, as well as L-arabinose that has no mediated transport. Fractional absorption (f) of L-arabinose was three times higher in the bat (S. lilium: 1.2±0.24) than in the rodent (A. montensis: 0.35±0.04), whereas f3OMD-glucose was complete in both species (1.46±0.4 vs. 0.97±0.12, respectively). In agreement, bats exhibited 2-12 times higher L-arabinose clearance per cm2 nominal surface area than rodents in intestinal perfusions. Using L-arabinose, we estimated that the contribution of the paracellular pathway to total glucose absorption was higher in all 3 bats (109-137%) than the rodents (13-39%). These findings contribute to an emerging picture that reliance on the paracellular pathway for nutrient absorption is much greater in bats relative to nonflying mammals and that this difference is driven by differences in intestinal permeability to nutrient-sized molecules.
Effects of natural and synthetic alarm pheromone and individual pheromone components on foraging behavior of the giant Asian honey bee,Apis dorsata
Authors: Li Jianjun , Wang Zhengwei , Tan Ken , Qu Yufeng , Nieh James 
Published: August 2014

AbstractSocial pollinators such as honey bees face attacks from predators not only at the nest, but also during foraging. Pollinating honey bees can therefore release alarm pheromones that deter conspecifics from visiting dangerous inflorescences. However, the effect of alarm pheromone and its chemical components upon bee avoidance of dangerous food sources remains unclear. We tested the responses of giant honey bee foragers, A. dorsata, presented with alarm pheromone at a floral array. Foragers investigated the inflorescence with natural alarm pheromone, but 3.3 fold more foragers preferred to land on the "safe" inflorescence without alarm pheromone. Using GC-MS analysis, we identified eight chemical components in the alarm pheromone, of which three components (1-octanol, decanal, and gamma-octanoic lactone) have not previously been reported in this species. We bioassayed six major compounds and found that a synthetic mixture of these compounds elicited behaviors statistically indistinguishable from responses to natural alarm pheromone. By testing each compound separately, we show that gamma-octanoic lactone, isopentyl acetate, and (E)-2-decen-1-yl acetate are active compounds that elicit significant alarm responses. Gamma-octanoic lactone elicited the strongest response to a single compound and has not been previously reported in honey bee alarm pheromone. Isopentyl acetate is widely found in the alarm pheromones of sympatric Asian honey bee species, and thus alarmed A. dorsata foragers may produce information useful for conspecifics and heterospecifics, thereby broadening the effects of alarm information on plant pollination.
Vertical Scope, Turbulence, and the Benefits of Commitment and Flexibility
Authors: Claussen Jörg , Kretschmer Tobias , Stieglitz Nils 
Published: August 2014

We address the contested state of theory and the mixed empirical evidence on the relationship between turbulence and vertical scope by studying how turbulence affects the benefits of commitment from integrated development of components and the benefits of flexibility from sourcing components externally. We show that increasing turbulence first increases but then decreases the relative value of vertical integration. Moderate turbulence reduces the value of flexibility by making supplier selection more difficult and increases the value of commitment by mitigating the status quo bias of integrated structures. Both effects improve the value of integration. Higher levels of turbulence undermine the adaptive benefits of commitment, but have a less adverse effect on flexibility, making nonintegration more attractive. We also show how complexity and uneven rates of turbulence moderate the nonmonotonic relationship between turbulence and integration. This paper was accepted by Jesper Sørensen, organizations.
From the Editor
Authors: van Ryzin Garrett J. 
Published: August 2014

It is indeed an honor to have been selected as the new editor-in-chief of Manufacturing & Service Operations Management. I look forward to my term of duty, and I am pleased to describe my plans for the journal. However, before doing so, I would first like to personally thank founding and outgoing Editor-in-Chief Leroy B. Schwarz for the superb job he has done in launching this journal. In the last four years, M&SOM has blossomed from a nonentity into the leading specialized journal in the field of operations management (OM). This is largely due to Lee's efforts and vision. We all owe him a tremendous debt of gratitude for this accomplishment. As incoming editor, I am especially indebted to Lee for the excellent reputation and goodwill he has generated for the journal. His will certainly be a tough act to follow. Like Lee, I truly believe the continued success of M&SOM is critical for our field. This is why I accepted the position of editor and why I am committed to making the journal an even greater success in the future. This task will no doubt require adjustments and revisions as time progresses. However, let me described my assessment of where the journal stands currently and my strategies and policies going forward.
What to expect when you're expecting? Representations of birth in British newspapers
Authors: Maclean Emily 
Published: August 2014

Background: National newspapers are a powerful force in British society, often portraying childbirth as a moment of high drama. Yet no evidence to date has systematically collated the material on offer. Objective: This descriptive study aimed to examine how childbirth is represented in British national newspapers. Methods: Content analysis of women's first-person accounts of birth was carried out. Text was coded using material gleaned from a database search of 23 publications over 12 months (from 1 December 2011 to 30 November 2012). Publications included Daily Mail, Mirror, The Telegraph, The Guardian, The Sun and The Times. Results: 61 codes emerged, including; fear, ordeal, pain, effective staff, malicious or poor care, intervention, humour, positive pain, relief, no choice, infection, no pain, mother's instinct. Conclusions: A discrepancy exists between newspaper messages and the majority of births. Uptake of normal birth pathways arguably depends on midwives addressing this potential source of anxiety. Distorted risk perceptions may also affect the behaviour of health practitioners, managers and commissioners.
Multi-function optical characterization and inspection of MEMS components using stroboscopic coherence scanning interferometry
Authors: Tapilouw Abraham Mario , Chen Liang-Chia , Xuan-Loc Nguyen , Chen Jin-Liang 
Published: August 2014

Abstract
A Micro-electro-mechanical-system (MEMS) is a widely used component in many industries, including energy, biotechnology, medical, communications, and automotive industries. However, effective inspection systems are also needed to ensure the functional reliability of MEMS. This study developed a stroboscopic coherence scanning Interferometry (SCSI) technique for measuring key characteristics typically used as criteria in MEMS inspections. Surface profiles of MEMS both static and dynamic conditions were measured by means of coherence scanning Interferometry (CSI). Resonant frequencies of vibrating MEMS were measured by deformation of interferogram fringes for out-of-plane vibration and by image correlation for in-plane vibration. The measurement bandwidth of the developed system can be tuned up to three megahertz or higher for both in-plane and out-of-plane measurement of MEMS.
Performance evaluation of the digital cell imaging analyzer DI-60 integrated into the fully automated Sysmex XN hematology analyzer system
Authors: Tabe Yoko , Yamamoto Takemasa , Maenou Imiko , Nakai Rie , Idei Mayumi , Horii Takashi , Miida Takashi , Ohsaka Akimichi 
Published: August 2014

AbstractThe XN-Series (Sysmex, Kobe, Japan) have been equipped with the automated digital cell imaging analyzer DI-60, which provides complete automation of the sample processing with automated complete blood counts (CBC), slide making/staining, and digital scanning with cell pre-classification. The aim of this study was to evaluate the efficacy of the XN-Series as an integrated blood cell analysis system.White blood cell (WBC) morphological analysis by the DI-60 was evaluated using 232 blood samples from patients. Routine analysis of a total of 2000 blood samples has been performed to evaluate the processing ability of the XN-Series connected to the DI-60.The overall analysis accuracy of pre-classification of WBC by the DI-60 was 88.4%. Good correlation was observed between final results of the DI-60 analysis and manual differentiation with high sensitivity and specificity for blasts and immature granulocytes. The sample processing time of the XN-Series, from automated CBC to cell pre-classification, was 38±1 min/single run and 165±12 min/500 CBC samples run (slide preparation rate 15.6%) with no sample hold-up at the DI-60.The automated morphological analysis capability of the DI-60 has potential usefulness in the integrated automated hematology analysis system of XN-Series.
Diagnostic testing for a high-grade inflammation: parameter dynamics and novel markers
Authors: Hoffmann Christina , Hoffmann Peter , Zimmermann Mathias 
Published: August 2014

AbstractThe timely detection of severe inflammatory conditions is of great importance for early therapy initiation and the patient’s prognosis. The complex humoral and cellular processes involved in inflammation offer many opportunities for diagnostic testing, which are still unused in clinical practice. We investigated the dynamics of four established and two novel potential markers during the onset and resolution of a high-grade inflammation.We retrospectively analyzed C-reactive protein and procalcitonin concentrations, leukocyte and thrombocyte counts, granularity index, and δ-hemoglobin measured in peripheral blood samples of patients undergoing inflammation diagnostics between September 2010 and November 2010. Data from a consecutive sample of 53,968 patients were available.Trajectories for the parameters’ dynamics during the onset and resolution of a high-grade inflammation were calculated with a locally weighted scatter plot smoothing method. The leukocyte count trajectories did not exceed the reference range.We were able to elucidate the parameter dynamics with time coordinates rounded to the nearest hour and a follow-up of 168 h.