bluuebunny/crossref_metadata_2025_split huggingface dataset:
Necrotizing fasciitis caused by Aeromonas caviae
Authors: Kumar Simit , Mukhopadhyay Prabir , Chatterjee Mitali , Bandyopadhyay Manas K , Bandyopadhyay Maitreyi , Ghosh Tapashi , Samaddar Debopriyo 
Published: April 2013

AbstractAeromonads are rarely associated with human intestinal and extra-intestinal diseases and syndromes, ranging from relatively mild illnesses such as acute gastroenteritis to life-threatening conditions, including septicemia, necrotizing fasciitis, and myonecrosis. Among the aeromonas species known to cause human infection, Aeromonas caviae has been associated with septicemia and only one reported case of human soft tissue infection. Most of the infections due to aeromonas occur in immunocompromised patients. Herein we describe a successfully treated case of post-traumatic skin and soft-tissue infections due to A. caviae in an otherwise immunocompetent individual.
O humor na literatura infantil: um estudo sobre leitura e apropriação de recursos humorísticos por crianças dos anos iniciais
Authors: Bonin Iara Tatiana , Silveira Rosa Maria Hessel 
Published: April 2013

O trabalho baseia-se na articulação entre o campo da literatura infantil e os estudos sobre humor e investiga as formas como alunos dos anos iniciais se apropriam de alguns recursos humorísticos em sua própria produção textual e imagética, após a realização de atividade com uma obra de literatura infantil (“Os chifres de Filomena”, de David Small) que incorpora elementos de humor. No estudo, aborda-se a questão do humor na literatura infantil, caracteriza-se a obra escolhida, descreve-se o trabalho realizado e interpreta-se a produção dos alunos, identificando-se, nela, a recriação de algumas estratégias de humor. Especula-se que tanto o caráter desafiador das atividades propostas quanto as características da obra, com seu final aberto, podem ter proporcionado a grande variedade de cenários, tramas e desfechos constatada nas produções das crianças.
Listening to Classical Music Ameliorates Unilateral Neglect After Stroke
Authors: Tsai Pei-Luen , Chen Mei-Ching , Huang Yu-Ting , Lin Keh-Chung , Chen Kuan-Lin , Hsu Yung-Wen 
Published: April 2013

Abstract
OBJECTIVE. We determined whether listening to excerpts of classical music ameliorates unilateral neglect (UN) in stroke patients.
METHOD. In this within-subject study, we recruited and separately tested 16 UN patients with a right-hemisphere stroke under three conditions within 1 wk. In each condition, participants were asked to complete three subtests of the Behavioral Inattention Test while listening to classical music, white noise, or nothing. All conditions and the presentation of the tests were counterbalanced across participants. Visual analog scales were used to provide self-reported ratings of arousal and mood.
RESULTS. Participants generally had the highest scores under the classical music condition and the lowest scores under the silence condition. In addition, most participants rated their arousal as highest after listening to classical music.
CONCLUSION. Listening to classical music may improve visual attention in stroke patients with UN. Future research with larger study populations is necessary to validate these findings.
Assessing the Driving Performance of a Person With Epilepsy Presurgery and Postsurgery
Authors: Crizzle Alexander M. , Classen Sherrilene , LaFranca Christina , Winter Sandra M. , Roper Steven N. , Eisenschenk Stephan 
Published: April 2013

Abstract
Occupational therapists and certified driving rehabilitation specialists are uniquely skilled to assess functional abilities underlying driving performance. However, little information exists on the utility of clinical assessments to determine driving performance in people with epilepsy. This case study demonstrates how an occupational therapy evaluation battery was used to examine differences in visual and cognitive abilities and simulated driving performance before and after epilepsy surgery. Specifically, a 43-yr-old White man with right anterior lobe epilepsy underwent temporal lobectomy and had his driving-related abilities and simulated driving performance assessed pre- and postsurgery. The occupational therapy evaluation indicated improvements in executive skills, attention, and information processing speed postsurgery. Visuospatial abilities worsened after surgery, likely contributing to the modest increase in vehicle position errors on the driving simulator. Nevertheless, simulated driving performance improved after temporal lobectomy. Reductions in the number of visual scanning, lane maintenance, and speed regulation errors were recorded.
Occupational Therapy for Patients With Acute Lung Injury: Factors Associated With Time to First Intervention in the Intensive Care Unit
Authors: Dinglas Victor D. , Colantuoni Elizabeth , Ciesla Nancy , Mendez-Tellez Pedro A. , Shanholtz Carl , Needham Dale M. 
Published: April 2013

AbstractOBJECTIVE. Very early occupational therapy intervention in the intensive care unit (ICU) improves patients’ physical recovery. We evaluated the association of patient, ICU, and hospital factors with time to first occupational therapy intervention in ICU patients with acute lung injury (ALI).METHOD. We conducted a prospective cohort study of 514 consecutive patients with ALI from 11 ICUs in three hospitals in Baltimore, MD.RESULTS. Only 30% of patients ever received occupational therapy during their ICU stay. Worse organ failure, continuous hemodialysis, and uninterrupted continuous infusion of sedation were independently associated with delayed occupational therapy initiation, and hospital study site and admission to a trauma ICU were independently associated with earlier occupational therapy.CONCLUSION. Severity of illness and ICU practices for sedation administration were associated with delayed occupational therapy. Both hospital study site and type of ICU were independently associated with timing of occupational therapy, indicating modifiable environmental factors for promoting early occupational therapy in the ICU.
Fibroepothelial polyp of the glans penis due to pad use for urinary incontinence
Authors: Kumsar Şükrü , Sağlam Hasan Salih , Dilek Hüsniye , Köse Osman , Budak Salih , Adsan Oztuğ 
Published: April 2013

A 78 year old man was admitted to our urology polyclinic with painless penile mass. The lesion was 3,5 cm in size on the ventral aspect of the penis. He had been using a pad for urinary incontinance for ten months but he said he had the lesion increasing in size for past 3 months. He underwent a wide local excision under local anesthesia. The histopathologic diagnosis was ﬁbroepithelial polyp. A fibroepithelial polyp of the penis is very rare and strongly linked to long-term condom catheter use. We present a case of fibroepithelial polyp of the glans which is not associated with condom catheter use.
General Introduction: The Elusive Boundary Between Fact And Value
Authors: Frederick William C. 
Published: April 2013

The question of how far, if at all, values invade, or should invade, the realm of empirical research is the focus of this issue of Business Ethics Quarterly. Readers will find a variety of answers and perspectives, along with some illustrative examples that support one or another of the possible views. Feelings run high on this topic, and they occasionally break through the normally staid atmosphere that one finds in most academic journals. That in itself may tell something about whether inquiry may be safely cordoned from a contaminating normative orientation. In form of presentation also, some of the articles selected by the editors vary from the conventional design. Essays and opinion pieces take their place alongside more formal presentations. Also included are two discussant papers.The original inspiration for this collection was a symposium presented during the 1992 annual meeting of the Social Issues in Management division of The Academy of Management. Held in Las Vegas, more than one attendee enjoyed the irony of business ethicists rubbing shoulders with gamblers and other related exotica found in Sin City. The symposium papers are grouped together and, with one exception, appear in the original order of presentation. They are followed by the two discussants’ comments. It is fair to say that in the intervening period, all of these authors have had second, or even third, thoughts and have revised their initial declarations somewhat. This echoes a time-honored practice in the U. S. Congress of allowing members to “extend their remarks” for the (official) Congressional Record, which is another way of giving politicians a chance to tell it the way they wished they had said it in the first place. That’s not bad in the case of academics also, if someone is careful to see that the “extensions” do not extend too far, and in that sense the editors have done what they could. The lead paper, though not part of the earlier symposium, is closely related to the general theme and is included for that reason.
Engagement radical, désengagement et déradicalisation. Continuum et lignes de fracture
Authors: Sommier Isabelle 
Published: April 2013

L’article s’attache à l’engagement radical entendu de façon classique comme un militantisme qui, à partir d’une posture de rupture vis-à-vis de la société d’appartenance, accepte au moins en théorie le recours à des formes non conventionnelles d’action politique éventuellement illégales, voire violentes. Il présente un bilan analytique des recherches qui adoptent de façon croissante une perspective de carrière et travaillent désormais sur le désengagement et la déradicalisation. Tout en refusant une interprétation particulariste et a fortiori pathologique du phénomène, il en restitue les spécificités et dynamiques collectives autant qu’individuelles pour souligner à la fois les continuités et les lignes de fracture le distinguant de l’engagement « ordinaire ».
Le désengagement d’organisations radicales. Approche par les processus et les configurations
Authors: Fillieule Olivier 
Published: April 2013

Un certain nombre d’études ont porté sur différents aspects de l’engagement et du désengagement des groupes clandestins, exclusifs et stigmatisés. Pourtant la recherche s’est concentrée sur les processus de recrutement et de radicalisation plus que sur le désengagement des organisations radicales. Dans ce texte, l’on s’appuie sur une approche en termes de carrière afin de proposer un modèle théorique du processus de désengagement des organisations radicales qui articule les niveaux micro (dispositions, socialisation), meso (façonnage organisationnel) et macro (contexte politique, répression et opportunités). La littérature opère souvent une distinction analytique entre ces trois niveaux d’analyse pour définir des séries de facteurs de l’engagement ou du désengagement, sans pourtant offrir une explication convaincante de la manière dont ils se combinent et se codéterminent dans le temps. Ici, nous faisons plutôt le choix de nous concentrer sur deux séries de facteurs centraux pour déterminer leur influence sur le processus de désengagement individuel : les effets complexes du façonnage organisationnel et les effets ambivalents de la répression et de la criminalisation des activités radicales.
Association of Epicardial Adipose Tissue With Cardiometabolic Risk and Metabolic Syndrome in Patients With Rheumatoid Arthritis
Authors: Ormseth Michelle J. , Lipson Aliza , Alexopoulos Nikolaos , Hartlage Gregory R. , Oeser Annette M. , Bian Aihua , Gebretsadik Tebeb , Shintani Ayumi , Raggi Paolo , Stein C. Michael 
Published: April 2013

ObjectivePatients with rheumatoid arthritis (RA) have increased coronary atherosclerosis possibly related to increased prevalence of visceral adiposity, insulin resistance, and metabolic syndrome. Epicardial adipose tissue (EAT), a type of visceral fat, may contribute to cardiometabolic risk. The aim of this study was to measure EAT volume in patients with RA and determine its relationship with cardiometabolic risk markers and coronary artery calcium.MethodsEAT volume and coronary artery calcium score were measured by noncontrast cardiac computed tomography and compared in RA patients (n = 162) and controls (n = 89). The relationships between EAT volume and markers of cardiometabolic risk in RA were examined with adjustment for age, race, and sex.ResultsAmong RA patients, EAT volume was positively associated with interleukin‐6 (P = 0.03), triglycerides (P = 0.004), hypertension (P = 0.01), homeostatic model of insulin resistance (HOMA) (P < 0.001), smoking history (P = 0.04), and homocysteine level (P = 0.001), and negatively associated with high‐density lipoprotein (P = 0.005). With further adjustment for waist circumference (a measure of visceral obesity), EAT volume remained independently associated with triglycerides, HOMA, current smoking, and homocysteine level (all P < 0.05). EAT volume was not associated with corticosteroid use or coronary artery calcium score. Patients with metabolic syndrome had significantly greater EAT volume (P < 0.001) and each increase in metabolic syndrome criteria was associated, on average, with a 20% increase (95% confidence interval 14–26%) in EAT volume (P < 0.001).ConclusionEAT volume is associated with metabolic syndrome and cardiometabolic risk factors, including insulin resistance, triglycerides, current smoking, and homocysteine levels, but not with coronary artery calcium in RA patients.
A Method for Fabricating an Ultrathin Multilayer Film Composed of Poly(p‐phenylenevinylene) and Reduced Graphene Oxide on a Plastic Substrate for Flexible Optoelectronic Applications
Authors: Wee Boon‐Hong , Hong Jong‐Dal 
Published: April 2013

AbstractThe photoconductive properties of a uniform ultrathin multilayer film composed of alternating poly(p‐phenylene vinylene) (PPV) and reduced graphene oxide (RGO) layers, fabricated on a poly(ethylene terephthalate) (PET) sheet are reported. The assembly of the two electron‐rich layer components on the temperature‐sensitive substrate is realized using a layer‐by‐layer‐deposition technique under mild conditions and HI/H2O vapor treatment at 100 °C. This protocol is established to simultaneously convert the layer components to their conjugated counterparts, PPV and RGO in the multilayer films, whose total thicknesses shrinks to 50% of their original values due to lattice contraction. Furthermore, the surface roughness decreases significantly, in contrast to the results obtained from general chemical treatments. The PET sheets coated with (PPV/RGO)15 films exhibit a photocurrent of 115 μA at an illumination intensity of 1.1 mW and a photoresponsivity of 111.1 mA W−1 at an illumination intensity of 0.5 mW; these are among the best values yet achieved in carbon‐based materials. The establishment of a method for fabricating (PPV/RGO) films on a temperature‐sensitive transparent flexible sheet is crucial for the development of organic‐based portable electronic devices.
Self‐Defensive Biomaterial Coating Against Bacteria and Yeasts: Polysaccharide Multilayer Film with Embedded Antimicrobial Peptide
Authors: Cado G. , Aslam R. , Séon L. , Garnier T. , Fabre R. , Parat A. , Chassepot A. , Voegel J.‐C. , Senger B. , Schneider F. , Frère Y. , Jierry L. , Schaaf P. , Kerdjoudj H. , Metz‐Boutigue M.‐H. , Boulmedais F. 
Published: April 2013

AbstractPrevention of pathogen colonization of medical implants is a major medical and financial issue since infection by microorganisms constitutes one of the most serious complications after surgery or critical care. Immobilization of antimicrobial molecules on biomaterials surfaces is an efficient approach to prevent biofilm formation. Herein, the first self‐defensive coating against both bacteria and yeasts is reported, where the release of the antimicrobial peptide is triggered by enzymatic degradation of the film due to the pathogens themselves. Biocompatible and biodegradable polysaccharide multilayer films based on functionalized hyaluronic acid by cateslytin (CTL), an endogenous host‐defensive antimicrobial peptide, and chitosan (HA‐CTL‐C/CHI) are deposited on a planar surface with the aim of designing both antibacterial and antifungal coating. After 24 h of incubation, HA‐CTL‐C/CHI films fully inhibit the development of Gram‐positive Staphylococcus aureus bacteria and Candida albicans yeasts, which are common and virulent pathogens agents encountered in care‐associated diseases. Hyaluronidase, secreted by the pathogens, leads to the film degradation and the antimicrobial action of the peptide. Furthermore, the limited fibroblasts adhesion, without cytotoxicity, on HA‐CTL‐C/CHI films highlights a medically relevant application to prevent infections on catheters or tracheal tubes where fibrous tissue encapsulation is undesirable.
Megalencephaly Syndromes and Activating Mutations in the PI3K‐AKT Pathway: MPPH and MCAP
Authors: MIRZAA GHAYDA M. , RIVIÈRE JEAN‐BAPTISTE , DOBYNS WILLIAM B. 
Published: April 2013

AbstractThe megalencephaly‐polymicrogyria‐polydactyly‐hydrocephalus (MPPH) and megalencephaly‐capillary malformation (MCAP) syndromes are highly recognizable and partly overlapping disorders of brain overgrowth (megalencephaly). Both syndromes are characterized by congenital or early postnatal megalencephaly, with a high risk for progressive ventriculomegaly leading to hydrocephalus and cerebellar tonsillar ectopia leading to Chiari malformation, and cortical brain abnormalities, specifically polymicrogyria. MCAP is further characterized by distinct cutaneous capillary malformations, finger or toe syndactyly, postaxial polydactyly, variable connective tissue dysplasia and mild focal or segmental body overgrowth, among other features. MPPH, on the other hand, lacks consistent vascular or somatic manifestations besides postaxial polydactyly in almost half of reported individuals. We identified de novo germline mutations in PIK3R2 and AKT3 in individuals with MPPH, and both postzygotic, mosaic and rare germline mutations in PIK3CA in individuals with MCAP. PIK3R2, AKT3, and PIK3CA are members of the critical phosphatidylinositol‐3‐kinase (PI3K)‐vakt murine thymoma viral oncogene homolog (AKT) pathway that is well implicated in cell growth, proliferation, survival, apoptosis, among other diverse cellular functions. The identified mutations in these three genes have been shown to lead to gain of function and activation of the PI3K‐AKT pathway. Germline and postzygotic mutations of PIK3CA and other PI3K‐AKT‐mTOR pathway genes have also been identified in several other overgrowth syndromes, highlighting the key role of this signaling pathway in normal development and pathophysiology of a large group of congenital anomalies. © 2013 Wiley Periodicals, Inc.
Aryl[2‐(hydroxypro‐2‐yl)cyclohyxyl]dimethylsilane: A Robust Aryl(trialkyl)silane Reagent for Nickel‐catalyzed Cross‐coupling Reactions with Aryl Tosylates
Authors: Tang Shi , Li Shu‐Hua , Nakao Yoshiaki , Hiyama Tamejiro 
Published: April 2013

AbstractA general route for the synthesis of an aryl(trialkyl)silane reagent, aryl[2‐(hydroxypro‐2‐yl)cyclohexyl]dimethylsilane, is demonstrated. By using a carbonate salt as an activator, the robust aryl(trialkyl)silane promotes nickel‐catalyzed aryl–aryl cross‐coupling reactions with aryl tosylates in a fluoride‐free and highly chemoselective manner. A reusable cyclic silyl ether was also quantitatively recovered.
Oxygen‐promoted Palladium‐on‐Carbon‐catalyzed Ligand‐free Suzuki Reaction for the Synthesis of Heterobiaryls in Aqueous Media
Authors: Rao Xiaofeng , Liu Chun , Xing Yang , Fu Yao , Qiu Jieshan , Jin Zilin 
Published: April 2013

AbstractWe report a practical and highly efficient protocol for the synthesis of heterobiaryls by a Pd/C‐catalyzed Suzuki reaction under aqueous, aerobic, and ligand‐free conditions. This ligand‐free catalytic system tolerates a broad range of functional groups in both coupling partners. A variety of heteroaryl halides were coupled with arylboronic acids to give the corresponding heterobiaryls in good to excellent yields. Moreover, the results demonstrated that the Pd/C‐catalyzed heterogeneous Suzuki reaction is promoted by oxygen.
Multimodal Sexual Signaling and Mating Behavior in Olive Baboons (Papio anubis)
Authors: RIGAILL LUCIE , HIGHAM JAMES P. , LEE PHYLLIS C. , BLIN AMANDINE , GARCIA CÉCILE 
Published: April 2013

AbstractIn primate species, mating decisions seem to be based on multiple signal elements with different roles in the signaling of female reproductive status. Whereas some primate signals are relatively well described (e.g., sexual swellings and copulation calls), studies that simultaneously assess visual, auditory, behavioral, and olfactory cues as signals of reproductive state are rarely undertaken. We used data on variation in sexual behaviors and sexual swellings in relation to the fertile period (estimated from the date of swelling detumescence) from a troop of semi‐free ranging olive baboons (Papio anubis) to assess how different signals influence patterns of mate choice. Using an objective and quantitative measure of swelling size and color, along with detailed data on sexual behaviors from 13 cycles of nine adult females, we found that fine‐scale variation in sexual swelling size, female behavior and copulation call rates could advertise the beginning of the fertile phase whereas swelling color did not. Rates of olfactory inspections by males also increased during the fertile phase, suggesting that olfactory signals were of interest to males and may contain information about ovulation. There was no relationship between female characteristics (age and rank) and the expression of sexual signals, except for proceptive behaviors which increased with female rank. Males displayed more sexual behaviors such as approaches and holding and tended to direct more ejaculatory mounts during the fertile phase. All together, we suggest that whereas all males could have information concerning the timing of ovulation through female proceptive behaviors and swelling size, consorting males may have access to additional signals (olfactory cues). Sexual communication in olive baboons is consistent with a multimodal framework for fertility signaling, potentially allowing males and females to establish different mating strategies. The possible selective pressures leading to multi‐modal signaling are discussed. Am. J. Primatol. 75:774–787, 2013. © 2013 Wiley Periodicals, Inc.
Brief communication: A proposed osteological method for the estimation of pubertal stage in human skeletal remains
Authors: Shapland Fiona , Lewis Mary E. 
Published: April 2013

ABSTRACTPuberty forms an important threshold between childhood and adulthood, but this subject has received little attention in bioarchaeology. The new application of clinical methods to assess pubertal stage in adolescent skeletal remains is explored, concentrating on the development of the mandibular canine, hamate, hand phalanges, iliac crest and distal radius. Initial results from the medieval cemetery of St. Peter's Church, Barton‐upon‐Humber, England suggest that application of these methods may provide insights into aspects of adolescent development. This analysis indicates that adolescents from this medieval site were entering the pubertal growth spurt at a similar age to their modern counterparts, but that the later stages of pubertal maturation were being significantly delayed, perhaps due to environmental stress. Continued testing and refinement of these methods on living adolescents is still necessary to improve our understanding of their significance and accuracy in predicting pubertal stages. Am J Phys Anthropol 151:302–310, 2013. © 2013 Wiley Periodicals, Inc.