bluuebunny/crossref_metadata_2025_split huggingface dataset:
Influence of Simulated Pulpal Pressure on Efficacy of Bleaching Gels
Authors: Torres Carlos Rocha Gomes , Batista Graziela Ribeiro , Borges Alessandra Bühler , Arantes Paula Tamião , Wiegand Annette , Attin Thomas 
Published: January 2015

ABSTRACTAimThe aim of this study was to investigate the influence of simulated pulpal pressure on efficacy of bleaching gels.Materials and methodsCylindrical enamel-dentin specimens from bovine teeth (3 mm diameter, enamel and dentin layer each 1 mm thick) were divided into 4 groups, according to the bleaching treatment: negative control (non-bleached), bleached with 10% carbamide peroxide (CP), bleached with 7.5% hydrogen peroxide (HP) and bleached with 35% hydrogen peroxide. Ten percent CP gel was applied for 8 h/day and 7.5% HP for 1 h/day, during 14 days. For 35% HP treatment, two sessions of 45 minutes each were employed. In intermediate periods specimens were stored in artificial saliva. Experimental groups (n = 19) were subdivided according to the simulation of pulpal pressure (25 mm Hg) during bleaching treatment. Initial color measurement and after bleaching treatment were assessed by spectrophotometry, using CIE L*a*b* system. The data were statistically analyzed by ANOVA and Dunnett's posthoc tests (p < 0.05).ResultsThere was significant difference of ∆E for all experimental groups compared to negative control group, according to Dunnett's test (p < 0.0001). There were no significant difference for total color variation (∆E) among experimental groups (p > 0.05).ConclusionIt was concluded that all bleaching gels showed bleaching efficacy compared to non-bleached group and that the simulated pulpal pressure did not influence the bleaching outcomes of the tested gels.Clinical significanceAlthough numerousin vitrostudies investigating the efficacy of bleaching agents have been performed, they do not properly simulate the pulpal pressure. In order to make these studies closer to clinical conditions, it is important to reproduce these conditions in laboratory, so the results can be more reliable. Thisin vitrostudy was performed under simulated pulpal pressure, aiming to investigate its influence on dental bleaching outcomes.How to cite this articleBorges AB, Batista GR, Arantes PT, Wiegand A, Attin T, Torres CRG. Influence of Simulated Pulpal Pressure on Efficacy of Bleaching Gels. J Contemp Dent Pract 2014;15(4):407-412.
Resistance of Teeth with Simulated Incomplete Rhizogenesis with Intraradicular Post or Root Canal Filling
Authors: Tanomaru-Filho Mario , Sivieri-Araujo Gustavo , Guerreiro-Tanomaru Juliane M , Bortoluzzi Eduardo A , Jorge Erica G , Abi-Rached Filipe O , Reis José Mauricio SN 
Published: January 2015

ABSTRACT

Aim
The aim of this study was to evaluate the fracture strength (FS) of bovine incisors with simulated incomplete rhizogenesis (IR) after different intraradicular treatments.

Materials and methods
Incomplete rhizogenesis was simulated by sectioning the crowns and roots of 40 bovine incisors. Root canal preparation was performed and the samples divided into 4 groups (n = 10): GI-negative control with intra-radicular preparation; GII-positive control without intra-radicular preparation; GIII-glass fiber post cemented with resin cement and GIVroot canal obturation with Epiphany/Resilon system. In GIII and GIV, 4.0 mm apical plugs of mineral trioxide aggregate (MTA) were done. The samples were embedded into cylinders with polystyrene resin, and the periodontal ligament was simulated with a medium-viscosity polyether-based impression material (Impregum Soft). The specimens were submitted to compressive fracture strength test (0.5 mm/min at 135o in relation to the long axis of the tooth) in a mechanical testing machine MTS 810. Data were submitted to ANOVA and Tukey's test (α = 0.05).

Conclusion
Glass fiber intraradicular posts provided the FS increase of teeth with simulated incomplete rhizogenesis. Epiphany/Resilon root canal filling with MTA plug did not provide the increase of the fracture strength to teeth with simulated incomplete rhizogenesis.

Clinical significance
The fiber post reinforces the root structure of teeth with incomplete rhizogenesis.

How to cite this article
Tanomaru-Filho M, Sivieri-Araujo G, Guerreiro-Tanomaru JM, Bortoluzzi EA, Jorge EG, Abi-Rached FO, Reis JMSN. Resistance of Teeth with Simulated Incomplete Rhizogenesis with Intraradicular Post or Root Canal Filling. J Contemp Dent Pract 2014;15(4):413-416.
Evaluation of the Effect of a Home Bleaching Agent on Surface Characteristics of Indirect Esthetic Restorative Materials—Part II Microhardness
Authors: Vojdani Mahroo , Torabi Kianoosh , Rasaeipour Sasan , Ghodsi Safoura , Khaledi Amir Ali Reza 
Published: January 2015

ABSTRACTBackgroundThe exponential usage of esthetic restorative materials is beholden to society needs and desires. Interaction between the bleaching agents and the esthetic restorative materials is of critical importance.AimThisin vitrostudy has been conducted to evaluate the effect of a home bleaching agent, carbamide peroxide (CP) 38%, on the microhardness of the fiber reinforced composite (FRC), overglazed, autoglazed, or polished porcelain specimens.Materials and methodsFor overglazed, autoglazed, polished ceramics and also FRC cylindrical specimens (n = 20 per group) were prepared. The specimens were stored in distilled water at 37°C for 48 hours prior to testing. Six samples from each group were selected randomly as negative controls which were stored in distilled water at 37°C that was changed daily. CP 38% was applied on the test specimens for 15 minutes, twice a day for 14 days. By using Knoop-microhardness tester microhardness testing for baseline, control and test specimens was conducted. Data were statistically analyzed using paired t-test, Mann- Whitney test, and Kruskal-Wallis test.ResultsHome bleaching significantly decreased the surface microhardness of all the test samples (p < 0.05), whereas the control groups did not show statistically significant changes after 2 weeks. The polished porcelain and polished composite specimens showed the most significant change in microhardness after bleaching process (p < 0.05).ConclusionAlthough the type of surface preparation affects the susceptibility of the porcelain surface to the bleaching agent, no special preparation can preclude such adverse effects.Clinical SignificanceThe contact of home bleaching agents with esthetic restorative materials is unavoidable. Therefore protecting these restorations from bleaching agents and reglazing or at least polishing the restorations after bleaching is recommended.How to cite this articleTorabi K, Rasaeipour S, Ghodsi S, Khaledi AAR, Vojdani M. Evaluation of the Effect of a Home Bleaching Agent on Surface Characteristics of Indirect Esthetic Restorative Materials — Part II Microhardness. J Contemp Dent Pract 2014;15(4):438-443.
An in vitro Evaluation of the Cytotoxicity of Varying Concentrations of Sodium Hypochlorite on Human Mesenchymal Stem Cells
Authors: Ahmad Zeeshan H , Alkahtany Sarah M , Anil Sukumaran 
Published: January 2015

ABSTRACT

Aim
To evaluate and compare the cytotoxicity of various concentrations of sodium hypochlorite on immortalized human bone marrow mesenchymal stem cells (MSCs).

Materials and methods
The 5.25 percent sodium hypochlorite (NaOCl) at concentrations of 0.5, 0.1, 0.025, 0.0125, and 0.005 mg/ml were used to assess the cytotoxic effect on MSCs. Immortalized human bone marrow mesenchymal stem cells (hTERT-MSCs) were exposed to NaOCl at 5 different concentrations. Cell viability was assessed by 3-(4, 5-dimethylthiazol- 2-yl)-2,5-diphenyltetrazolium bromide (MTT) and alamarBlue assays. The cell morphology changes were assessed with scanning electron microscopy (SEM) after exposure to 2, 4, and 24 hour incubation. The ethidium bromide/acridine orange (EB/ AO) fluorescent stain was applied to the cells in the 8-chamber slides after they were incubated with the testing agents for 2 and 4 hours to detect live and dead cells. The observations were quantitatively and qualitatively analyzed.

Results
The cell viability study using MTT assay and AB assay showed significant reduction with varying concentration at 2 and 4 hours incubation period. The cell viability decreased with the higher percentage of NaOCl. The exposure time also revealed an inverse relation to the cell viability. The SEM analysis showed reduction in the number of cells and morphological alterations with 0.5 mg/ml at 2 and 4 hours compared to 0.025 mg/ml NaOCl. Destruction of the cells with structural alterations and lysis was evident under fluorescence microscope when the cells were exposed to 0.5 mg/ml NaOCl.

Conclusion
Within the limitations of this in vitro study it can be concluded that NaOCl is toxic to the human bone marrow MSCs. The cell lysis was evident with higher concentration of sodium hypochlorite. From the observations, it can be concluded that a lower concentration of NaOCl may be used as endodontic irrigant due to its cytotoxic properties. Further studies are man datory to evolve a consensus on the optimal concentration of sodium hypochlorite to be used as endodontic irrigant.

How to cite this article
Alkahtani A, Alkahtany SM, Anil S. An in vitro Evaluation of the Cytotoxicity of Varying Concentrations of Sodium Hypochlorite on Human Mesenchymal Stem Cells. J Contemp Dent Pract 2014;15(4):473-481.
Oral Health-related Quality of Life and Periodontal and Dental Health Status in Iranian Hemodialysis Patients
Authors: Hajian-Tilaki Arefe , Oliae Farshid , Jenabian Niloofar , Hajian-Tilaki Karimollah , Motallebnejad Mina 
Published: January 2015

ABSTRACTAimThe aim of this study was to evaluate oral health status and oral health related quality of life (OHRQoL) in Iranian patients undergoing hemodialysis.Materials and methodsIn this cross-sectional study 145 (95 dentate and 50 edentulous) patients undergoing hemodialysis participated. Demographic information, laboratory findings and dental health status was recorded by a standard form. Oral hygiene status was obtained by simplified oral hygiene index (OHI-S) and oral health was evaluated by decay missing filling teeth (DMFT) index, plaque index (PLI) and periodontal disease index. Oral health related quality of life was determined by means of short form oral health impact profile (OHIP-14) and general oral health assessment index (GOHAI).ResultsThe mean (± SD) DMFT, PLI and PDI were 15.47 ± 7.85, 2.03 ± 0.95, 4.09 ± 1.31 respectively. OHI-S was good in 7 (7.4%), fair 25 (26.6%) and poor in 38 (26.6%) of patients. The mean OHIP-14 and GOHAI scores were 31.32 ± 12.53 and 29.07 ± 8.5 respectively. The self-perceived oral health of 58 (40%) was good, 49(33.8%) was fair and 38 (26.2%) was poor. Patients with higher scores for the questionnaires had significantly worst self-rated oral health. Besides, there was a significant positive correlation between dental and periodontal variables with OHIP-14 and GOHAI scores.ConclusionHemodialysis patients had a poor oral hygiene and periodontal status, weak attitudes and negligence toward oral health but they were satisfied of their oral health condition and their OHRQoL was approximately good. Therefor it should be communications between nephrologists and oral health care professionals for promoting the oral health status of the patients.Clinical significanceThe findings high light the need of comprehensive oral examinations including periodontal therapy, restorative treatment, preventive dental treatment and follow-up care in the hemodialysis patients.How to cite this articleHajian-Tilaki A, Oliae F, Jenabian N, Hajian-Tilaki K, Motallebnejad M. Oral Health-related Quality of Life and Periodontal and Dental Health Status in Iranian Hemodialysis Patients. J Contemp Dent Pract 2014;15(4):482-490.
Atraumatic Extraction, Implant Placement and Immediate Provisionalization
Authors: Bandéca Matheus Coelho , de Jesus Tavarez Rudys Rodolfo , Malheiros Adriana Santos , Firoozmand Leily Macedo , Filho Etevaldo Matos Maia , Calixto Amanda Martins , Gomes Mario Gilson Nina 
Published: January 2015

ABSTRACTFront tooth extraction typically results in significant loss of hard and soft tissue volume, both in the vestibular-lingual and mesiodistal directions. As these changes can compromise the esthetic results of prosthetic rehabilitation, extraction techniques that cause minimal trauma to the remnant tissues are applied in combination with immediate implant placement to minimize such alterations. The case reported in the present article illustrates a therapeutic plan consisting of atraumatic extraction followed by immediate implant placement and provisionalization. When carefully indicated and planned, our results indicate that this technique may provide promising immediate results relative to the maintenance and stability of the peri-implanted tissues.How to cite this articlede Jesus Tavarez RR, Calixto AM, Filho EMM, Bandeca MC, Firoozmand LM, Gomes MGN, Malheiros AS. Atraumatic Extraction, Implant Placement and Immediate Provisionalization. J Contemp Dent Pract 2014;15(4):513-517.
A41. Breve história de um armário de doações e suas implicações
Authors: Lima Solange Ferraz de 
Published: January 2015

A proposta do presente artigo é refletir sobre as práticas recorrentes e cotidianas que consubstanciam a cultura visual contemporânea a partir de objetos visuais doados ou adquiridos por um museu de história e sobre as práticas museológicas que proporcionam novo patamar de observação e fruição desses mesmos objetos, agora tomados como documentos. Duas questões emergem de imediato quando colocamos atenção nas práticas acumuladoras e colecionistas dentro ou fora de espaços institucionalizados: em que medida esses objetos visuais podem ser considerados de interesse para tratar da visualidade da sociedade contemporânea e quais os efeitos sociais provocados pelas políticas de coleta de acervos dos museus.
Práticas musicais de jovens e vida cotidiana: socialização e identidades em movimento
Authors: Souza Jusamara , Quintal de Freitas Maria de Fatima 
Published: January 2015

Este artigo aborda questões vinculadas a práticas musicais de jovens que vivenciam a música com diferentes mídias. Tomando a perspectiva teórica dos estudos sobre a vida cotidiana, o objetivo é analisar discursos, conceitos, métodos e resultados da produção de conhecimento musical específicos da juventude quando mediados pelas tecnologias. Dentre os aspectos analisados destaca-se a formação de identidades e socialização considerando a música como um signo geracional. Essas categorias contribuem para uma compreensão empiricamente fundamentada sobre o papel que as mídias exercem para os jovens em suas aprendizagens musicais. As reflexões e análises permitem uma compreensão ampliada das interfaces entre música, educação e identidades sociais.
Análisis longitudinal de tesis doctorales españolas en educación (1841-2012)
Authors: Fernández-Bautista Andrés , Torralbo Manuel , Fernández-Cano Antonio 
Published: January 2015

Este artículo analiza la producción investigadora de tesis doctorales del campo de la educación defendidas en España desde 1841 a 2012. Ofrece una visión cuantificada, global y diacrónica de tal serie. Como hito a destacar está el hecho de que hasta 1954, la obtención del grado de doctor estuvo centralizada en la Universidad de Madrid. Se utilizan como motores de búsqueda las bases de datos bibliográficas: TESEO y repositorios institucionales, y bibliografía básica del área para llevar a cabo la recopilación de la muestra. La hipótesis a contraste trata de verificar si la serie temporal se ajusta parcialmente al modelo de crecimiento de la ciencia propuesto por Dereck J. de Solla Price. El hallazgo central es que la producción española de tesis doctorales en educación sigue un modelo cuasi-logístico con una preocupante tendencia de caída en los últimos doce años
Improved identification and enrolment into care of HIV‐exposed and ‐infected infants and children following a community health worker intervention in Lilongwe, Malawi
Authors: Ahmed Saeed , Kim Maria H , Dave Amanda C , Sabelli Rachael , Kanjelo Kondwani , Preidis Geoffrey A , Giordano Thomas P , Chiao Elizabeth , Hosseinipour Mina , Kazembe Peter N , Chimbwandira Frank , Abrams Elaine J 
Published: January 2015

BackgroundEarly identification and entry into care is critical to reducing morbidity and mortality in children with HIV. The objective of this report is to describe the impact of the Tingathe programme, which utilizes community health workers (CHWs) to improve identification and enrolment into care of HIV‐exposed and ‐infected infants and children.MethodsThree programme phases are described. During the first phase, Mentorship Only (MO) (March 2007–February 2008) on‐site clinical mentorship on paediatric HIV care was provided. In the second phase, Tingathe‐Basic (March 2008–February 2009), CHWs provided HIV testing and counselling to improve case finding of HIV‐exposed and ‐infected children. In the final phase, Tingathe‐PMTCT (prevention of mother‐to‐child transmission) (March 2009–February 2011), CHWs were also assigned to HIV‐positive pregnant women to improve mother‐infant retention in care. We reviewed routinely collected programme data from HIV testing registers, patient mastercards and clinic attendance registers from March 2005 to March 2011.ResultsDuring MO, 42 children (38 HIV‐infected and 4 HIV‐exposed) were active in care. During Tingathe‐Basic, 238 HIV‐infected children (HIC) were newly enrolled, a six‐fold increase in rate of enrolment from 3.2 to 19.8 per month. The number of HIV‐exposed infants (HEI) increased from 4 to 118. During Tingathe‐PMTCT, 526 HIC were newly enrolled over 24 months, at a rate of 21.9 patients per month. There was also a seven‐fold increase in the average number of exposed infants enrolled per month (9.5–70 patients per month), resulting in 1667 enrolled with a younger median age at enrolment (5.2 vs. 2.5 months; p<0.001).During the Tingathe‐Basic and Tingathe‐PMTCT periods, CHWs conducted 44,388 rapid HIV tests, 7658 (17.3%) in children aged 18 months to 15 years; 351 (4.6%) tested HIV‐positive. Over this time, 1781 HEI were enrolled, with 102 (5.7%) found HIV‐infected by positive PCR. Additional HIC entered care through various mechanisms (including positive linkage by CHWs and transfer‐ins) such that by February 2011, a total of 866 HIC were receiving care, a 23‐fold increase from 2008.ConclusionsA multipronged approach utilizing CHWs to conduct HIV testing, link HIC into care and provide support to PMTCT mothers can dramatically improve the identification and enrolment into care of HIV‐exposed and ‐infected children.
Gulf of Alaska continental slope morphology: Evidence for recent trough mouth fan formation
Authors: Swartz John M. , Gulick Sean P. S. , Goff John A. 
Published: January 2015

AbstractGlaciated continental shelves are host to numerous morphologic features that help understand past glacier dynamics. Southeastern Alaska is home to the St. Elias mountains, an active orogen that also hosts temperate marine glaciers. During glacial periods ice streams advance across the continental shelf, carving shelf‐crossing troughs that reach the shelf edge. We use high‐resolution multibeam data to develop the relationship between the Yakutat and Alsek Sea Valleys and the resulting continental slope morphology. The shelf and slope geomorphology can be divided into statistical groupings that relate to the relative balance of erosion and deposition. Our analysis indicates that only the Yakutat system has been able to build an incipient trough‐mouth fan. The extreme sediment supply from this region was able to overwhelm the steep initial topography of the transform margin while further to the east sediment slope‐bypass dominates. This analysis provides an extreme end member to existing studies of temperate glaciation along continental margins. The unique interplay between rapid uplift due to ongoing collision and the massive erosion caused by temperate glaciers provides for sedimentary flux far above most other systems.
Transferability in the future climate of a statistical downscaling method for precipitation in France
Authors: Dayon G. , Boé J. , Martin E. 
Published: January 2015

AbstractA statistical downscaling approach for precipitation in France based on the analog method and its evaluation for different combinations of predictors is described, with focus on the transferability of the method to the future climate. First, the realism of downscaled present‐day precipitation climatology and interannual variability for different combinations of predictors from four reanalyses is assessed. Satisfactory results are obtained, but elaborated predictors do not lead to major and consistent across‐reanalyses improvements. The downscaling method is then evaluated on its capacity to capture precipitation trends in the last decades. As uncertainties in downscaled trends due to the choice of the reanalysis are large and observed trends are weak, this analysis does not lead to strong conclusions on the applicability of the method to a changing climate. The temporal transferability is then assessed thanks to a perfect model framework. The statistical downscaling relationship is built using present‐day predictors and precipitation simulated by 12 regional climate models. The entire projections are then downscaled, and future downscaled and simulated precipitation changes are compared. A good temporal transferability is obtained only with a specific combination of predictors. Finally, the regional climate models are downscaled, thanks to the relationship built with reanalyses and observations, for the best combination of predictors. Results are similar to the changes simulated by the models, which reinforces our confidence in the realism of the models and of the downscaling method. Uncertainties in precipitation change due to reanalyses are found to be limited compared to those due to regional simulations.
Cost‐Effectiveness Analysis of Two Rituximab Retreatment Regimens for Longstanding Rheumatoid Arthritis
Authors: Quartuccio Luca , di Bidino Rossella , Ruggeri Matteo , Schiavon Franco , Biasi Domenico , Adami Silvano , Punzi Leonardo , Cicchetti Americo , de Vita Salvatore 
Published: January 2015

ObjectiveRituximab (RTX) is licensed for second‐line treatment of rheumatoid arthritis (RA) after first tumor necrosis factor (TNF) inhibitor failure. RTX is generally administered intravenously at 1 gm 2 weeks apart, and the retreatment is scheduled at the time of clinical relapse (regimen 1). A more intensive regimen is proposed with a fixed full cycle after 6 months (regimen 2) if remission is not reached. A cost‐effectiveness analysis (CEA) compared these 2 regimens of RTX administration in patients with longstanding RA based on data provided by an observational study.MethodsAn observational retrospective study was conducted on 102 patients, enrolled in 3 hospitals and followed for ≥12 months. Forty‐seven patients followed regimen 1, while 55 patients followed regimen 2. A CEA based on a Markov model was conducted. A lifelong and social perspective was adopted. CEA was conducted for the entire cohort and for the 2 subgroups separately (patients with positive rheumatoid factor and/or anti–cyclic citrullinated peptide and failures to TNF inhibitors).ResultsResults for the overall sample show at 10, 20, and 30 years that regimen 1 is less costly and associated with a higher quality of life compared to regimen 2. Probabilistic sensitivity analysis at 10 years estimated a probability of 95.1% for regimen 1 to be cost effective given a willingness to pay of €35,000/quality‐adjusted life year, while for seropositive patients and for TNF failures it was estimated to be 92% and 92.7%, respectively.ConclusionIn longstanding RA, cost effectiveness of RTX retreatment at clinical relapse was found to be at least equivalent to the more intensive regimen proposed.