bluuebunny/crossref_metadata_2025_split huggingface dataset:
Climate change and resilience of the Senegalese health system in the face of the floods in Keur Massar
Authors: Diallo Abdoulaye Moussa , Ridde Valery 
Published: August 2024

AbstractThis article is based on the observation that the affected populations perceive existing community‐based adaptation strategies to the health effects of floods differently. We explore the resilience of the local health system to climate change (CC) in Keur Massar (Senegal) using a monographic approach based on a qualitative survey of flooded households, health professionals, hygiene agents, community health actors, administrative and local authorities, agents from the Ministries of Health and Environment, and experts from the ecological and meteorological monitoring centre (n = 72). The effects of CC on health are modulated by financial, organisational, social and cultural factors. The effects of CC on health are modulated by traditionally praised by self‐centred health governance, which is often based on standardisation of problems and thus not sufficiently attuned to local contexts, especially the climate vulnerability index (CVI) of households and health structures. Despite the existence of programs to combat the consequences of CC, the notorious lack of exhaustive mapping of areas with a high CVI hinders the effective management of the health of the affected populations. A typology of forms of mobility in the context of flooding—ground floor to the upper floor, borrowing a room, renting a flat, seasonal residence—reveals inequalities in access to care as well as specific health needs management of vector‐borne diseases, discontinuity of maternal, newborn and child health care, and psychosocial assistance. The article outlines how a health territorialisation based on surveillance and response mechanisms can be co‐constructed and made sustainable in areas with a high CVI. Integrating this approach into national health policies allows for equity in health systems efficiently and sustainably.
Cancer‐associated fibroblasts derived exosomal LINC01833 promotes the occurrence of non‐small cell lung cancer through miR‐335‐5p ‐VAPA axis
Authors: Chen Jie , Sun Jian‐jun , Ma Ya‐wen , Zhu Meng‐qin , Hu Jing , Lu Qi‐jue , Cai Zhi‐gang 
Published: August 2024

AbstractCancer‐associated fibroblasts (CAFs) are an important component of the tumor microenvironment (TME) and can induce functional polarization of tumor macrophages. This study aimed to explore the effect of CAFs‐derived exosome LINC01833 on the malignant biological behavior of non‐small cell lung cancer (NSCLC) cells and its mechanism. Tumor tissues (n = 3) and adjacent noncancerous tissues (n = 3) were collected from patients with NSCLC, and fibroblasts (CAF, NF) were isolated from the two tissues. Expression of LINC01833/miR‐335‐5p/VAPA in NSCLC clinical tissues and cell lines was detected by RT‐qPCR. Exosomes of CAFs and NFs were isolated by ultracentrifugation. Cell proliferation, migration, invasion, and M2 macrophage polarization were detected by MTT, transwell, wound‐healing assay, and flow cytometry assay, while western blot was used to verify the expression of M2 macrophage polarization‐related proteins. Tumor volume weight and M2 macrophage polarization were detected by tumor xenografts in nude mice. LINC01833 was highly expressed in NSCLC tumor tissues and cells. Knockdown of LINC01833 exosomes could significantly inhibit proliferation, migration, invasion of NSCLC cells, and M2 macrophage polarization of THP‐1 cells, while simultaneous knockdown of miR‐335‐5p on the above basis could reverse the effect of knockdown of LINC01833. In vivo experiments also indicated that knockdown of LINC01833 exosomes suppressed tumor growth and M2 macrophage polarization. CAF‐derived LINC01833 exosomes can promote the proliferation, migration and invasion of NSCLC cells and M2 macrophage polarization by inhibiting miR‐335‐5p and regulating VAPA activity.
Improved biochemical and neurodevelopmental profiles with high‐dose hydroxocobalamin therapy in cobalamin C defect
Authors: Olivieri Giorgia , Greco Benedetta , Cairoli Sara , Catesini Giulio , Lepri Francesca Romana , Orazi Lorenzo , Mallardi Maria , Martinelli Diego , Ricci Daniela , Simeoli Raffaele , Dionisi‐Vici Carlo 
Published: August 2024

AbstractCobalamin C (Cbl‐C) defect causes methylmalonic acidemia, homocystinuria, intellectual disability and visual impairment, despite treatment adherence. While international guidelines recommend parenteral hydroxocobalamin (OH‐Cbl) as effective treatment, dose adjustments remain unclear. We assessed OH‐Cbl therapy impact on biochemical, neurocognitive and visual outcomes in early‐onset Cbl‐C patients treated with different OH‐Cbl doses over 3 years. Group A (n = 5), diagnosed via newborn screening (NBS), received high‐dose OH‐Cbl (median 0.55 mg/kg/day); Group B1 (n = 3), NBS‐diagnosed, received low‐dose OH‐Cbl (median 0.09 mg/kg/day); Group B2 (n = 12), diagnosed on clinical bases, received low‐dose OH‐Cbl (median 0.06 mg/kg/day). Biochemical analyses revealed better values of homocysteine, methionine and methylmalonic acid in Group A compared to Group B1 (p < 0.01, p < 0.05 and p < 0.01, respectively) and B2 (p < 0.001, p < 0.01 and p < 0.001, respectively). Neurodevelopmental assessment showed better outcome in Group A compared to low‐dose treated Groups B1 and B2, especially in Developmental Quotient, Hearing and Speech and Performance subscales without significant differences between Group B2 and Group B1. Maculopathy was detected in 100%, 66% and 83% of patients in the three groups, respectively. This study showed that “high‐dose” OH‐Cbl treatment in NBS‐diagnosed children with severe early‐onset Cbl‐C defect led to a significant improvement in the metabolic profile and in neurocognitive outcome, compared to age‐matched patients treated with a “low‐dose” regimen. Effects on maculopathy seem unaffected by OH‐Cbl dosage. Our findings, although observed in a limited number of patients, may contribute to improve the long‐term outcome of Cbl‐C patients.
Dynamic aspects of investigative interviewing high‐status fraud suspects
Authors: Hoekstra Manon R. 
Published: August 2024

AbstractHigh‐status financial fraudsters can inflict significant financial and social damage on society. This study aims to provide insight into the dynamics during investigative interviews with such suspects. To this end, 409 half‐hour episodes of audio‐recorded investigative interviews with 28 high‐status suspects were analysed. Officers’ interview techniques are classified in four categories (rapport building; disclosure of potential evidence; adopting a challenging posture; authoritative signalling). Suspects' statements are classified into three categories (general disclosure; providing alternative explanations; uncertain statement behaviour). The dynamic relations between interviewers’ questions and suspects’ statements are studied, both within and across half‐hour episodes.
Ultrastructure of the extraordinary pedal gland in Asplanchna aff. herricki (Rotifera: Monogononta)
Authors: Hochberg Rick , Wallace Robert L. , Walsh Elizabeth J. , Araújo Thiago Q. 
Published: August 2024

AbstractRotifers possess complex morphologies despite their microscopic size and simple appearance. Part of this complexity is hidden in the structure of their organs, which may be cellular or syncytial. Surprisingly, organs that are cellular in one taxon can be syncytial in another. Pedal glands are widespread across Rotifera and function in substrate attachment and/or egg brooding. These glands are normally absent in Asplanchna, which lack feet and toes that function as outlets for pedal glandular secretions in other rotifers. Here, we describe the ultrastructure of a pedal gland that is singular and syncytial in Asplanchna aff. herricki, but is normally paired and cellular in all other rotifers. Asplanchna aff. herricki has a single large pedal gland that is active and secretory; it has a bipartite, binucleate, syncytial body and a cytosol filled with rough endoplasmic reticulum, Golgi, and several types of secretory vesicles. The most abundant vesicle type is large and contains a spherical electron‐dense secretion that appears to be produced through homotypic fusion of condensing vesicles produced by the Golgi. The vesicles appear to undergo a phase transition from condensed to decondensed along their pathway toward the gland lumen. Decondensation changes the contents to a mucin‐like matrix that is eventually exocytosed in a “kiss‐and‐run” fashion with the plasma membrane of the gland lumen. Exocytosed mucus enters the gland lumen and exits through an epithelial duct that is an extension of the syncytial integument. This results in mucus that extends from the rotifer as a long string as the animal swims through the water. The function of this mucus is unknown, but we speculate it may function in temporary attachment, prey capture, or floatation.
Image‐Generated Word‐of‐Mouth: A Catalyst for Visiting Friends and Relatives (VFR) Tourism?
Authors: Bakri Marlini , Richard James E. , Krisjanous Jayne 
Published: August 2024

ABSTRACTThis research introduces and tests the concept of image‐generated word‐of‐mouth (iWOM), extending the scope of visual rhetoric and emotional contagion theories. Using collected paired data and PLS‐based structural equation modeling, this study examines the role of sojourners as adept visual influencers and of their images as critical marketing vehicles in VFR tourism. The findings demonstrate that sojourner iWOM influences the overall impression of receiving friends and relatives, a key mechanism that facilitates an intention to visit/engage in VFR tourism. Additionally, this study clarifies the intervening role of tie strength in the consumption of iWOM between two subgroups (friends/relatives), where tie strength is only found to strengthen the effectiveness of iWOM in shaping the perceptions and subsequently, visit intentions of the friends subgroup. Collectively, the findings provide initial insights into using online initiatives in marketing to target the difficult‐to‐reach VFR segment—a key segment in post‐crisis recovery.
Energy‐Efficient Integrated Photonic Topological Devices
Authors: Zhang Zijian , Liao Dashuang , Li Yuanzhen , Xie Xinrong , Yang Yumeng , Wang Kai , Dong Zhaozhen , Li Erping , Chen Hongsheng , Gao Fei 
Published: August 2024

AbstractTopological photonics is revolutionizing the integrated electromagnetic devices, on account of the robust mode propagations immune to structural defects and sharp bends. Such robust modes have spawned attractive devices known as photonic topological waveguides (PTW), especially implemented on compact photonic‐crystal platforms. However, these exotic waveguides are challenging to be high‐efficiently interconnected with conventional integrated photonic devices. To tackle this challenge, a general energy‐efficient strategy for topological photonic structures is proposed. Such strategy is implemented onto three types of typical PTWs, which extract electromagnetic energy high efficiently from standard single‐mode rectangular waveguides. Moreover, the results of dual‐polarization valley PTW proves the polarization‐independence of their strategy. The measured near‐perfect excitation efficiencies are stable across the whole operational band of topological waveguides, thus verifying the frequency independence of this strategy. By utilizing this energy‐efficient strategy, an integrated topological high‐gain antenna, which achieves the peak directive gain of 20.25 dBi and half power beam width of 5.23° at 60 GHz, is realized. This strategy on energy‐efficient design is general to be applicable on other types of topological photonic platforms and paves the way for applications of topological electromagnetic devices.
Ultra‐Fast, Fine‐Resolution Thin‐Film Lithium Niobate Spectrometer
Authors: Liang Wei , Lin Zhongjin , Wang Yifei , Hu Junlie , Li Binneng , Lin Yanmei , Zhu Yuntao , Yu Siyuan , Cai Xinlun 
Published: August 2024

AbstractAchieving rapid spectroscopic characterization is highly desirable for contactless, real‐time monitoring applications. However, it is challenging due to the trade‐off between short acquisition time and fine resolution. To address this challenge, a fully active scanning Fourier transform spectrometer (FTS) using thin‐film lithium niobate (TFLN) photonics is proposed. This work theoretically reveals relations between acquisition time and resolution and finds that their trade‐off can be notably alleviated by employing Michelson interferometer architectures. The proposed device consists of two broadband edge couplers and a tunable Michelson interferometer which includes 1.02 m‐length equivalent waveguides. The fabricated waveguides can achieve a wafer‐scale optical propagation loss of 12 2.4 dB , which enables the device to maintain a low insertion loss with a 1.02 m‐length equivalent waveguide. The proposed device can achieve an acquisition time of 10 , a spectral resolution of 0.74 (i.e., 0.19 nm), and an operation wavelength range from 1260 to 1600 nm.
Ultrafast‐Laser‐Induced Nanostructures with Continuously Tunable Period on Au Surface for Photoluminescence Control in Monolayer MoS2
Authors: Chen Zhicheng , Jiang Lan , Sun Jingya , Wang Feifei , Yang Yang , Zhang Ruochen , Lin Gen 
Published: August 2024

AbstractNanostructures of noble metal offer an exciting opportunity to tune photoluminescence (PL) in 2D materials, which has shown promise for applications in plasmonic devices. However, an efficient, designable, residue‐free nanofabrication method remains challenging. Herein, a one‐step ultrafast laser nanofabrication method is performed in fabrication of laser induced periodic surface structure (LIPSS) with continuously tunable periods over a wide range (from 439 to 2086 nm) on Au. The process of LIPSS imprinting is revealed at different time scales: periodical energy deposition within hundreds of femtoseconds, phase transition after 10 ps, and resolidification after 200 ps. Furthermore, the intensity and peak shift of PL in monolayer MoS2 (1L‐MoS2) can be tuned by LIPSS, 11‐fold enhancement resulting from nanoscale confinement of the incident laser and exciton‐trion localized interconversion emanating from hot electron transfer and tensile strain. The results are promising for 2D‐materials/metal heterostructures to applications in plasmonic devices and nanophotonic integrated circuits.
Finely Controlled Circularly Polarized Luminescence with Multimode Dynamic Response of Hybrid Metal Chlorides for Circularly Polarized White Light‐Emitting Diode and Programmable Information Encryption
Authors: Wang Luying , Peng Hui , Wei Qilin , Kong Linghang , Yu Shuiyue , Cao Jiajun , Liang Qihua , Zhao Jialong , Zou Bingsuo 
Published: August 2024

AbstractStimulus‐responsive materials that exhibit efficient circularly polarized luminescence (CPL) have gained much interest for application in advanced smart photonics. Herein, the CPL‐active enantiomorphic 0D Sb3+‐doped (R/S)2InCl7 (R/S = R/S‐2‐methylpiperazine) are synthesized via a solution method. They show efficient broadband yellow emission with a near‐unity photoluminescence quantum yield and a CPL asymmetry factor of 1.7 × 10−3. Their fascinating chiroptical activity should be attributed to the chirality transfer and self‐trapped exciton emission caused by strong electron–phonon interaction. Particularly, H2O‐induced structural transformation is demonstrated to obtain non‐emission of Sb3+‐doped (R/S)2InCl7·H2O after exposure to a humid environment. Importantly, Sb3+‐doped (R/S)2InCl7 exhibits unique nonlinear optical responses, and the rotation angle between the quarter‐wave plate and linearly polarized plate can regulate the reversible switching of Sb3+‐doped (R/S)2InCl7 between yellow emission and negligible luminescence. Moreover, a circularly polarized white light‐emitting diode is fabricated by combining blue phosphors BaMgAl10O17:Eu2+, and the device exhibits tunable switching control of positive and warm white light by regulating the rotation angle of linear polarizer plate. Based on the tunable optical responses of Sb3+‐doped (R/S)2InCl7, a programmable multi‐mode fluorescence encoding system is constructed, and four‐level information encryption and three‐level encrypted 3D color codes are also realized in a further proof‐of‐concept experiment.
Exploring the dynamic landscape of immunopeptidomics: Unravelling posttranslational modifications and navigating bioinformatics terrain
Authors: Flender Daniel , Vilenne Frédérique , Adams Charlotte , Boonen Kurt , Valkenborg Dirk , Baggerman Geert 
Published: August 2024

AbstractImmunopeptidomics is becoming an increasingly important field of study. The capability to identify immunopeptides with pivotal roles in the human immune system is essential to shift the current curative medicine towards personalized medicine. Throughout the years, the field has matured, giving insight into the current pitfalls. Nowadays, it is commonly accepted that generalizing shotgun proteomics workflows is malpractice because immunopeptidomics faces numerous challenges. While many of these difficulties have been addressed, the road towards the ideal workflow remains complicated. Although the presence of Posttranslational modifications (PTMs) in the immunopeptidome has been demonstrated, their identification remains highly challenging despite their significance for immunotherapies. The large number of unpredictable modifications in the immunopeptidome plays a pivotal role in the functionality and these challenges. This review provides a comprehensive overview of the current advancements in immunopeptidomics. We delve into the challenges associated with identifying PTMs within the immunopeptidome, aiming to address the current state of the field.
Electrokinetic Properties of Cellulose Diacetate—Influence of Morphology and Crystallinity on the Zeta Potential
Authors: Kramar Ana , Luxbacher Thomas , González‐Benito Javier 
Published: August 2024

AbstractThe study presents the electrokinetic properties of the zeta potential and the isoelectric point for cellulose diacetate (CA) in the forms of powder, nonporous film, and porous film. Surface zeta potential (ζ) and isoelectric point (IEP) are important properties that reflect the material's behavior in contact with liquids, as a consequence of the surface charge density and the morphology of the material. Nonporous films are prepared by casting CA solution on glass and Teflon dishes, while the porous film is prepared by the solution blow spinning (SBS) technique. The ζ potential is determined using the streaming potential method in the pH range from 2.5 to 9.5. The influence of the material's crystallinity (CI) and surface roughness (Sa) on the zeta potential is studied. The form of the material (powder, porous film, or nonporous film) influences the electrokinetic properties, which may have consequences on their behavior in contact with liquid (e.g., for processes such as oxidation, surface modification, grafting, or aging during use).
Facile and Effective Method for the Preparation of Sodium Alginate/TiO2 Bio‐Composite Films for Different Applications
Authors: Paradisi E. , Mortalò C. , Russo P. , Zin V. , Miorin E. , Montagner F. , Leonelli C. , Deambrois S. M. 
Published: August 2024

AbstractNanocomposites of sodium alginate (SA) and TiO2 nanoparticles have gained attention in the last decade for their versatile uses in several applications. Indeed, TiO2 is particularly appealing for its photocatalytic and antimicrobial activity and inherent safety. In this paper, TiO2 nanoparticles are successfully embedded, synthesized by a microwave‐assisted method, into SA matrix by a simple solvent casting method to form flexible and self‐consistent SA/TiO2 films. FT‐IR, XRD, and contact angle measurements confirm the formation of homogeneous and hydrophilic bio‐composites films that may be suitable for packaging or life science applications.
Characterization of Grapeseed Oil Loaded Chitosan Edible Films
Authors: Zsivanovits Gabor , Marudova Maria , Viraneva Asya , Gechev Biser , Zhelyazkov Stoil , Iliev Angel 
Published: August 2024

AbstractEssential oil loaded edible films are good alternatives of petroleum‐based polymer packaging materials for extending the shelf‐life of perishable fruits. This work studies the influence of grapeseed oil concentration on the physical and antioxidant properties of chitosan‐based edible films. The multicomponent films are softer and more stretchable than the pure chitosan films. An increase in the oil concentration increases the antioxidant activity and the hydrophobicity of the films, which is expressed in a decrease in the affinity for water uptake and a change in their surface energy. The surface color and the transparency of the films are optimal at low oil concentration. The evaluated physical and physicochemical properties show the potential of these films to reduce the food waste.
Bio‐Based Thermosetting Resins from Waste Cooking Oil
Authors: Palucci Benedetta , Vignali Adriano , Ravasio Nicoletta , Zaccheria Federica , Bertini Fabio 
Published: August 2024

AbstractIn order to face the environmental concern about the use of traditional fossil‐based monomers for the production of thermosetting resins, herein this study reports the synthesis of bio‐based materials from waste cooking oil (WCO). In this context, this study explores the epoxidation‐acrylation strategy for the synthesis of the starting functionalized oil for the production of thermosetting resins composed of only WCO‐derived monomers or in combination with terpenic comonomers such as limonene and myrcene. Furthermore, employing myrcene as comonomer produces thermosetting resins that reveal the best properties in terms of mechanical strength if compared to the homopolymer ones.
Sustainable Materials for Corrosion Protection on Aircraft Structures
Authors: Orrico Marianna , Tescione Fabiana , Silvestri Brigida , de Gennaro Bruno , Stanzione Mariamelia 
Published: August 2024

AbstractThe corrosion of metal surfaces is one of the most critical issues in aviation, where aircraft are subjected to very extreme climatic and operating conditions. Hexavalent chromium, Cr (VI), based coatings provide an effective corrosion protection at relatively low cost, but unfortunately their usage has a significant impact on the environment. To comply with new regulations (REACH) and to ensure effectiveness against corrosion, the current interest of researchers and investors is focused on the synthesis and the design of eco‐friendly and safer coatings, to develop an alternative and innovative corrosion protection coating systems, characterized by specific performance in terms of good adhesion, barrier, and rheological properties. The development of innovative materials and the implementation of new technologies can allow widening the safety window in all the process phases from the production to the disposal. These research activities are focused on the development of anticorrosive and chromate‐free coatings, by modifying metal‐based primer formulations. The aim is toward the improvement in the anticorrosive performance and durability respect to the systems already known in the literature through the incorporation of sustainable compounds or less toxic metals as corrosion inhibitors to reduce the environmental impact.