bluuebunny/crossref_metadata_2025_split huggingface dataset:
A randomised controlled trial of roller versus centrifugal cardiopulmonary bypass pumps in patients undergoing pulmonary endarterectomy
Authors: Mlejnsky F , Klein A A , Lindner J , Maruna P , Kvasnicka J , Kvasnicka T , Zima T , Pecha O , Lips M , Rulisek J , Porizka M , Kopecky P , Kunstyr J 
Published: September 2014

Objectives: There is some controversy as to whether there is a benefit from the use of a centrifugal pump compared with a roller pump during cardiopulmonary bypass to facilitate cardiac surgery. We compared the two pumps, with the primary aim of determining any difference in the effects on inflammation after pulmonary endarterectomy surgery which required prolonged cardiopulmonary bypass and deep hypothermic circulatory arrest. Methods: Between September 2010 and July 2013, 58 elective patients undergoing pulmonary endarterectomy were included in this prospective, randomised, controlled study; 30 patients were randomly allocated to the control group, which used a roller pump, and 28 patients to the treatment group, which used a centrifugal pump. Interleukin-6, procalcitonin, C-reactive protein, thromboelastographic parameters, P-selectin, international normalised ratio, activated prothrombin time, free haemoglobin, haematocrit, red blood cell count, white blood cell count, platelet count and protein S100β were recorded during and after the procedure. We also recorded the length of intensive care unit stay, blood loss and transfusion, neurological outcomes and respiratory and renal failure. Results: There was a significant difference in the primary outcome measure: Interleukin-6 was significantly higher in the roller pump group (587±38 ng·l-1 vs. 327±37 ng·l-1; p<0.001) 24 hours after surgery, which we interpreted as an increased inflammatory response. This was confirmed by a significant rise in the procalcitonin level in the roller pump group 48 hours following surgery (0.79 (0.08-25.25) ng·ml-1 vs. 0.36 (0.02-5.83) ng·ml-1; p<0.05). There were, however, no significant differences in clinical outcome data. Conclusions: We have shown that the use of a centrifugal pump during prolonged cardiopulmonary bypass and deep hypothermic circulatory arrest is associated with a reduced inflammatory response compared to the standard roller pump. Larger multi-centre trials in this area of practice are required.
Sixteen‐year follow‐up of Barrett's esophagus, endoscopically treated with argon plasma coagulation
Authors: Milashka Mariana , Calomme Annabelle , Van Laethem Jean Luc , Blero Daniel , Eisendrath Pierre , Le Moine Olivier , Devière Jacques 
Published: September 2014

ObjectiveThe thermal destruction of non‐dysplastic Barrett's esophagus (BE) and its replacement by squamous epithelium is an attractive, but unproven strategy to avoid further development of dysplasia or cancer.The goal of this study was to estimate the persistence of restoration of squamous epithelium and the risk of cancer in BE that was eradicated using argon plasma coagulation (APC) in the absence of high‐grade dysplasia, 16 years after its application.DesignWe followed 32 patients with BE who underwent eradication of metaplastic epithelium using APC, up to 16 years later.ResultsAt the end of the initial treatment, 25 of 32 patients (78%) had complete endoscopic eradication, there was partial squamous re‐epithelialization in four patients (13%) and it was absent in three patients (9%). We observed buried metaplastic glands under new squamous epithelium in 6 of the 25 patients who had complete endoscopic eradication. At follow‐up, sustained complete endoscopic eradication was observed in 16 of 32 patients (50%), partial eradication in 11 of 32 patients (35%); there were two patients (6%) lost to follow‐up and three patients (9%) developed esophageal adenocarcinoma. Two of the latest cases arose from the buried glands under neosquamous epithelium after complete eradication and one arose from a small remaining Barrett's segment.ConclusionsWe observed long‐term re‐epithelialization in the majority of patients who had previously had complete eradication of Barrett's esophagus. This did not provide protection against cancer development, as the incidence of cancers arising from buried glands or from residual Barrett's esophagus was similar to that observed in patients undergoing no specific treatment.
Near-infrared optical absorption enhanced in black silicon via Ag nanoparticle-induced localized surface plasmon
Authors: Zhang Peng , Li Shibin , Liu Chunhua , Wei Xiongbang , Wu Zhiming , Jiang Yadong , Chen Zhi 
Published: September 2014

Abstract
Due to the localized surface plasmon (LSP) effect induced by Ag nanoparticles inside black silicon, the optical absorption of black silicon is enhanced dramatically in near-infrared range (1,100 to 2,500 nm). The black silicon with Ag nanoparticles shows much higher absorption than black silicon fabricated by chemical etching or reactive ion etching over ultraviolet to near-infrared (UV-VIS-NIR, 250 to 2,500 nm). The maximum absorption even increased up to 93.6% in the NIR range (820 to 2,500 nm). The high absorption in NIR range makes LSP-enhanced black silicon a potential material used for NIR-sensitive optoelectronic device.

PACS

78.67.Bf; 78.30.Fs; 78.40.-q; 42.70.Gi
Prediction of deep-buried gas carbonate reservoir by combining prestack seismic-driven elastic properties with rock physics in Sichuan Basin, southwestern China
Authors: Ma Jiqiang , Geng Jianhua , Guo Tonglou 
Published: September 2014

The prediction of seismic reservoirs in marine carbonate areas in the Sichuan Basin, southwestern China, is very challenging because the target zone is deeply buried (more than 6 km), with multiphase tectonic movements, complex diagenesis, and low porosity, and the incident angle of the seismic data is finite. We developed reliable hydrocarbon indicators of a marine carbonate deposit based on prestack elastic impedance (EI) and well observations. Although the hydrocarbon indicators can be calculated from elastic parameters, the inversion for EI-driven elastic attributes is usually unstable. To constrain the inversion process, we discovered a new strategy to recover the elastic properties from EIs within a Bayesian framework (called Bayesian elastic parameter inversion from elastic impedance). We applied the strategy to a carbonate reef identified at the center of a study line based on the geologic context and the seismic reflection patterns. We then used rock-physics analyses to classify the lithologies and the reservoir at a well location. Rock-physics modeling quantified the hydrocarbon sensitivity of the elastic attributes. Fluid substitution was used to investigate the effects of pore fluids on the elastic properties. A comparison of two synthetic amplitude-versus-angle responses (for gas and brine saturation) with real seismic data showed that the reservoir was gas charged. Using well-based crossplot analyses, reliable direct hydrocarbon indicators can be constructed for a deeply buried gas reservoir and were effective for interpretation in an area of marine carbonates in the Sichuan Basin.
Clinical and Molecular Features of Hürthle Cell Carcinoma of the Thyroid
Authors: Chindris Ana-Maria , Casler John D. , Bernet Victor J. , Rivera Michael , Thomas Colleen , Kachergus Jennifer M. , Necela Brian M. , Hay Ian D. , Westphal Sydney A. , Grant Clive S. , Thompson Geoffrey B. , Schlinkert Richard T. , Thompson E. Aubrey , Smallridge Robert C. 
Published: September 2014

Abstract

Context:
Hürthle cell cancer (HCC) of the thyroid remains the subject of controversy with respect to natural course, treatment, and follow-up.

Objective:
The objective of the study was to evaluate the clinical and molecular features associated with outcome in HCC.

Design:
The study was a review of 173 HCC cases treated at Mayo Clinic over 11 years with a median 5.8-year follow-up.

Results:
None of the patients with minimally invasive histology had persistent disease, clinical recurrence, or disease-related death. Male gender and TNM stage were independently associated with increased risk of clinical recurrence or death in widely invasive patients. The 5-year cumulative probability of clinical recurrence or death was higher in patients with TNM stage III–IV (females, 74%; males, 91%) compared with patients with TNM stage I–II (females, 0%; males, 17%). Pulmonary metastases were best identified by computed tomography, whereas radioactive iodine scans were positive in only two of 27 cases. Thyroglobulin was detectable in patients with clinical disease, with the notable exception of five patients with distant metastases. The common TERT C228T promoter mutation was detected in both widely invasive and minimally invasive tumors. TERT mRNA was below the limit of detection in all samples.

Conclusion:
Widely invasive HCC with TNM stage III–IV is aggressive, with low probability of recurrence-free survival. Males have worse outcomes than females. Minimally invasive HCC appears to be considerably less aggressive. Radioactive iodine scan performs poorly in detecting distant disease. Although the TERT gene is mutated in HCC, the role of this mutation remains to be demonstrated.
Kebijakan Perguruan Tinggi Negeri Yogyakarta Terhadap Penyandang Disabilitas
Authors: Soleh Akhmad 
Published: September 2014

This study discusses the accessibility of university education in the four public universities in Yogyakarta; Indonesian Arts Institute (ISI), University of Gajah Mada (UGM),Yogyakarta State University (UNY), and State Islamic University (UIN) Sunan Kalijaga. Upto now, the disability groups have not got an equal access and the opportunity in a higher education. There are only a few students with disabilities that are accepted in Universities in Indonesia, because of physical limitations that would interfere the teaching-learning process in their classrooms. The research findings showed that the education systems in the UGM, Yogyakarta State University, and the ISI have a system of “integration”, while at UIN has led to the inclusion system, that is “accommodative” and has the ability to service for persons with disabilities.Penelitian ini membahas tentang aksesibilitas pendidikan di perguruan tinggi di empat perguruan tinggi negeri di Yogyakarta; yaitu Institut Seni Indonesia (ISI), Universitas Gajah Mada (UGM), Universitas Negeri Yogyakarta (UNY), an Universitas Islam Negeri (UIN) Sunan Kalijaga. Sampai saat, kelompok masyarakat yang menyandang disabilitas masih belum memperoleh persamaan dan kesempatan dalam mengakses pada pendidikan tinggi. Hanya sedikit mahasiswa penyandang disabilitas yang diterima pada Perguruan tinggi di Indonesia, karena keterbatasan fisik yang akan mengganggu proses belajar-mengajar di kelasnya. Hasil penelitian menunjukkan baha pendidikan di UGM, UNY, dan ISI memiliki sistem “integrasi”,sedangkan di UIN telah memiliki sistem inklusi, yang “akomodatif”, dan mampu memberi layanan mahasiswa penyandang disabilitas.
Kebijakan Pendidikan Islam: Hibridasi Lembaga Pendidikan Tinggi
Authors: Wahyono Andi 
Published: September 2014

This paper is going to discuss and to provide solutions for the problems of dualism policy in the Islamic higher education institution. The effort to integrate religious education and general education has not reached a satisfactory result. Several concepts have been offered, but they still leave the problems off dualism policy in the Islamic higher education institution. Therefore, I offer the concept of hybridization of higher educations. This endeavor is very urgent to be done because there is a tendency of Islamic higher education institutions and general higher education institutions to be more apart, although there are the offers of conceptof science Islamization, Islam as Science, or the integration and interconnection of science.Tulisan ini hendak mempersoalkan sekaligus memberi solusi terhadap permasalahan dualisme kebijakan lembaga pendidikan tinggi islam. Upaya memadukan pendidikan agama dan pendidikan umum belum sampai pada kata memuaskan. Beberapa konsep sudah ditawarkan namun masih menyisakan persoalan berupa dualisme kebijakan lembaga pendidikan tinggi Islam. Oleh karena itu, saya menawarkan konsep tentang hibridasi lembaga pendidikan tinggi. Usaha ini sangat mendesak untuk dilakukan karena ada kecenderungan lembaga pendidikan tinggi Islam dan lembaga pendidikan tinggi umum justru semakin berjalan sendiri-sendiri, sekalipun sudah ada tawaran konsep tentang Islamisasi ilmu, Islam sebagai ilmu, ataupunintegrasi dan interkoneksi keilmuan.
A parabolic flow of balanced metrics
Authors: Bedulli Lucio , Vezzoni Luigi 
Published: September 2014

Abstract
We prove a general criterion to establish existence and uniqueness of a short-time solution to an evolution equation involving “closed” sections of a vector bundle, generalizing a method used by Bryant and Xu [8] for studying the Laplacian flow in

G
2

$G_{2}$

-geometry. We apply this theorem in balanced geometry introducing a natural extension of the Calabi flow to the balanced case. We show that this flow has always a unique short-time solution belonging to the same Bott–Chern cohomology class of the initial balanced structure and that it preserves the Kähler condition. Finally, we study explicitly the flow on the Iwasawa manifold.
Induced characters with equal degree constituents
Authors: Gagola, Jr. Stephen M. , Sezer Sezgin 
Published: September 2014

Abstract
We study the situation of a finite group G having
a subgroup H with the property that each of its nonprincipal
irreducible (complex) characters induce to G as a sum of irreducible
characters all having the same degree. When this happens, the subgroup
H either contains, or is contained in, the commutator subgroup G'
of G. In any case, the normal closure HG
is always proper in G
whenever H is proper (even when G is perfect), and HG
is solvable
whenever this normal closure is a proper subgroup of G'.
Übersicht zu Sensordatenfusionsansätzen in der Thermografie
Authors: Soldan Samuel , Kroll Andreas 
Published: September 2014

Zusammenfassung
In diesem Beitrag wird eine Übersicht über verschiedene Ansätze
gegeben, um durch Fusion bzw.
Kombination von mehreren, unterschiedlichen Aufnahmen
die Qualität des thermografischen Messergebnisses zu verbessern und/oder
die Menge an nutzbaren Informationen über ein Messobjekt zu
erhöhen. Dabei wird sowohl die Kombination
verschiedener Thermografiedaten (uni-modale
Fusion), als auch die Sensordatenfusion mit anderen
bildgebenden Messverfahren (multi-modale Fusion)
behandelt.
ZIPCO, a putative metal ion transporter, is crucial for Plasmodium liver‐stage development
Authors: Sahu Tejram , Boisson Bertrand , Lacroix Céline , Bischoff Emmanuel , Richier Quentin , Formaglio Pauline , Thiberge Sabine , Dobrescu Irina , Ménard Robert , Baldacci Patricia 
Published: September 2014

AbstractThe malaria parasite, Plasmodium, requires iron for growth, but how it imports iron remains unknown. We characterize here a protein that belongs to the ZIP (Zrt‐, Irt‐like Protein) family of metal ion transport proteins and have named ZIP domain‐containing protein (ZIPCO). Inactivation of the ZIPCO‐encoding gene in Plasmodium berghei, while not affecting the parasite's ability to multiply in mouse blood and to infect mosquitoes, greatly impairs its capacity to develop inside hepatocytes. Iron/zinc supplementation and depletion experiments suggest that ZIPCO is required for parasite utilization of iron and possibly zinc, consistent with its predicted function as a metal transporter. This is the first report of a ZIP protein having a crucial role in Plasmodium liver‐stage development, as well as the first metal ion transporter identified in Plasmodium pre‐erythrocytic stages. Because of the drastic dependence on iron of Plasmodium growth, ZIPCO and related proteins might constitute attractive drug targets to fight against malaria.
Horizontal Well Placement Optimization for Heavy-Oil Production in Complex Heterogeneous and Thin Reservoirs: A Case Study from the South China Sea
Authors: Luo Donghong , Li Lin , Tao Bin , Halomoan P. M. , Bisain A. S. , Wang Chao 
Published: September 2014

AbstractLocated in offshore South China, Panyu oil field has entered into mature development phase after a decade of intensive production the water cut of the field had raised to 91%. It was then decided to start targeting less than 5m thin heavy oil reservoirs with density 0.93 - 0.96 g/cm3, 14-17API Gravity and with dynamic viscosity of 275 cP to increase the production and reserve recovery of the overall field. The only way to extract heavy oil from these reservoirs was from drilling horizontal wells.However, exploiting these targets presents operational challenges with increasing complexity with heterogeneous formation, presence of bottom water and heavy oil property. To overcome, need strategic well planning, the horizontal well needs to be optimally placed within complex target zone, the lateral also needs to be placed as close as possible to the reservoir top to keep it away from the unknown current fluid contact and design a completion to minimize water conning.This paper features the best practices of making strategic planning and spacing of horizontal wells in the field for efficient draining of the reservoir, drilling of horizontal wells close to top of reservoir to optimize the distance between horizontal section and oil water contact that is very sensitive to well performance and reserve recovery. This includes precise landing with low incident angle and lateral placement within less than 0.5m window below the reservoir top utilizing the directional electromagnetic and wellbore imaging applications for detail reservoir profiles description and current OWC level identification while drilling and further designing a completion in a combination of step screen and stinger to balance the pressure drawdown along the lateral for minimizing the water coning.Multiple wells' field cases will be discussed in the paper based on 16 horizontal wells completed during the course of the project. Several key outcomes that have been observed during the execution and upon the completion of the well will be highlighted, including: –Clear identification of the reservoir geo-bodies and their interfaces including the current fluid contact level–Optimum lateral placement in the best position to drain the reservoir–Completion design for optimal productionThe authors conclude that heavy oil reserve recovery enabled through horizontal wells drilling and completion program. The implementation of the best practices in operation is the key to drain the heavy oil effectively and optimally.
Optimizing Navigation Well-Path Design on Thin-Bed, Highly Stratified Heavy-Oil Reservoirs by Using Seismic Attributes and Well Logs, Rubiales Field, Eastern Llanos Basin, Colombia
Authors: Penaloza Edinson David , Nunez Fernando Jose 
Published: September 2014

Normally, oil fields develop, once the exploratory phase and reservoir delineation are concluded, is performed based on a geometric arrangement that involves the spacing of wells according to their drainage radius and therefore avoid drain areas overlap.
The Rubiales field in the eastern plains of Colombia is characterized by high stratification and sand thicknesses of economic interest that are on average below 10 feet and are mostly drained horizontally on having only 3-4 feet Net Pay although in specific cases, have been drilled thicknesses less than 2 feet, always coexisting with the water and having to manage it for doing this field economically profitable. Generally speaking, could be considered a reservoir of low structural complexity.
However compiled drilling experience in thin beds has shown problems questioning lateral continuity of sand bodies in the original length of the paths well designed, affecting the forecasted production commitment, raising operational risk having to make changes on well paths during drilling and finishing doing “pilot holes” being already in horizontal sections to resizing the stratigraphy and the placement of sand bodies and lateral continuity involved.
This job is a compilation of some experiences obtained at Rubiales field having seismic data as support and powerful tool for minimizing risk of total or partial navigation target loss in heavy oil thin beds reservoirs.
Complex Well Design for Multilaterals Offshore North Caspian Sea
Authors: Valisevich Alexey , Zvyagin Vasiliy , Famiev Robert , Kozhakhmetov Mirat , Paramonov Alexey , Akhmetov Marat 
Published: September 2014

Abstract
The success of the drilling campaign including drilling efficiency, service quality, personnel safety and cost is critically dependent on robust solutions developed during the design phase of the overall well construction process.
One of the most critical stages of the overall well construction process is the well design phase. The drilling project service quality, personnel safety, drilling efficiency and cost directly depend on the robust solutions elaborated at the design phase.
This paper describes the advanced technical engagement between an operator and an integrated services company to generate a basis of design for drilling and completing development wells in the Filanovskogo offshore field, in the north of Caspian Sea. The basis of design is a document that describes well design principles, engineering solutions and technologies required to drill and complete the wells. The paper explains the design approach selected by the project team, project design stages, foreseen challenges and technical solutions to deliver efficient well designs that could meet operator requirements and comply with Russian regulatory rules.
The key technical challenges of the Filanovskogo field are that the reservoir zone is located at shallow true vertical depth (TVD); the high formation collapse gradients and low mud loss gradients create a narrow mud weight window environment, along with complicated well profiles involving – multilateral horizontals and extended reach (ER) wells. This paper illustrates the development of a basis of design to ensure cost-effective access to reserves. It covers the operator and the service company experience in the drilling of ERD wells, applying advanced technologies for windows milling, completion options screening process and designing a multilateral junction. It also provides an understanding of the importance of operator and service company departments integration processes in order to achieve well objectives. To support the basis of design development, a comprehensive risk register was generated to minimize drilling risks.
The process of technical integration between the operator and the service company in the early stages of operational planning by developing drilling and completion design is unique for Russian O&G operators and was done by assuming that it would be very efficient through providing technical integrity and minimizing the project risks. The drilling and completion design consideration processes described in this paper can be used to provide valuable insight for future projects where up-front complex technical study is key to success.