bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh Infrastruktur Terhadap Pertumbuhan Ekonomi Di Kota Subulussalam
Authors: Tatang Syahban Adi Syahputra  , Purba Elidawaty , Damanik Darwin 
Published: August 2024

Penelitian ini bertujuan untuk mengetahui pengaruh Infrastruktur Jalan, Infrastruktur air, dan Infrastruktur Listik terhadap pertumbuhan Ekonomi di kota Subulussalam. Jenis data yang digunakan dalam penelitian ini adalah data sekunder deret waktu (time series data) yang diperoleh dari Badan Pusat Statistik Kota Subulussalam (BPS) dan literatur lainnya yang berhubungan dengan penelitian ini. Data menggunakan data tahunan yang terhitung dari tahun 2010 - 2020. Metode analisis yang digunakan adalah analisis deskriptif dan analisis kuantitatif. Dengan model regresi berganda dan menggunakan teknik Ordinary Least Square (OLS), Prosedur Analisis Data menggunakan Pengujian Asumsi Klasik yaitu Uji Normalitas, Uji Multikolinearitas, Uji Heteroskedastisitas dan Uji Hipotesis yaitu Uji t, Uji F dan Koefisien Determinasi (R2). Hasil penelitian menjelaskan bahwa Infrastruktur Jalan (X1) tidak berpengaruh signifikan terhadap pertumbuhan Ekonomi di Kota Subulussalam, Infrastruktur air (X2) berpengaruh signifikan terhadap pertumbuhan ekonomi di Kota Subulussalam, Infrastruktur Listik (X3) tidak berpengaruh signifikan terhadap pertumbuhan ekonomi di Kota Subulussalam. Dan Infrastruktur Jalan (X1), infrastruktur air (X2), dan infrastruktur listrik (X3) berpengaruh signifikan secara bersama-sama terhadap pertumbuhan ekonomi di Kota Subulussalam
Human leukocyte antigen compatibility and incidence of donor-specific antibodies in pediatric liver transplant recipients
Authors: Melere Melina U , Feier Flavia H , Neumann Jorge , Kalil Antônio N , Montagner Juliana de M , Nader Luiza S , da Silva Carolina S , Junior Marco Aurélio F , Coral Gabriela P , Bobsin Guilherme P , Ferreira Cristina T 
Published: August 2024

BACKGROUND
Antibody-mediated rejection following liver transplantation (LT) has been increasingly recognized, particularly with respect to the emergence of de novo donor-specific antibodies (DSAs) and their impact on graft longevity. While substantial evidence for adult populations exists, research focusing on pediatric LT outcomes remains limited.
AIM
To investigate the prevalence of human leukocyte antigen (HLA) mismatches and DSA and evaluate their association with rejection episodes after pediatric LT.
METHODS
A cohort of pediatric LT recipients underwent HLA testing at Santa Casa de Porto Alegre, Brazil, between December 2013 and December 2023. Only patients who survived for > 30 days after LT with at least one DSA analysis were included. DSA classes I and II and cross-matches were analyzed. The presence of de novo DSA (dnDSA) was evaluated at least 3 months after LT using the Luminex® single antigen bead method, with a positive reaction threshold set at 1000 MFI. Rejection episodes were confirmed by liver biopsy.
RESULTS
Overall, 67 transplanted children were analyzed; 61 received grafts from living donors, 85% of whom were related to recipients. Pre-transplant DSA (class I or II) was detected in 28.3% of patients, and dnDSA was detected in 48.4%. The median time to DSA detection after LT was 19.7 [interquartile range (IQR): 4.3-35.6] months. Biopsy-proven rejection occurred in 13 patients at follow-up, with C4d positivity observed in 5/13 Liver biopsies. The median time to rejection was 7.8 (IQR: 5.7-12.8) months. The presence of dnDSA was significantly associated with rejection (36% vs 3%, P < 0.001). The rejection-free survival rates at 12 and 24 months were 76% vs 100% and 58% vs 95% for patients with dnDSA anti-DQ vs those without, respectively.
CONCLUSION
Our findings highlight the importance of incorporating DSA assessment into pre- and post-transplantation protocols for pediatric LT recipients. Future implications may include immunosuppression minimization strategies based on this analysis in pediatric LT recipients.
Analisis Perbandingan Rencana Anggaran Biaya (RAB) Metode Konvensional Dengan Metode Building Information Modeling (BIM) (Studi Kasus Gedung 3 Lantai Di Yogyakarta)
Authors: Fitriono Fahrizal , Haza Zainul Faizien , Shulhan M. Afif 
Published: August 2024

Seiring dengan perkembangan zaman, industri di bidang infrastruktur berkembang sangatlah cepat dan pesat, hal itu juga dibarengi dengan kemajuan teknologi yang semakin maju dan berkembang, akibatnya menuntut para penyedia jasa konstruksi untuk memanfaatkan kemajuan teknologi agar perkerjaan kontstruksi bisa lebih tepat, cepat, efektif, efisien dan akurat. Penelitian ini dilakukan untuk mengetahui hasil dari perbandingan perhitungan Rencana Anggaran Biaya (RAB) menggunakan metode Konvensional dengan metode Building Information Modelling (BIM). Hasil yang di dapat dari perbandingan volume beton dan tulangan metode Building Information Modelling (BIM) lebih rendah dari metode Konvensional dengan selisih volume beton dan tulangan yaitu berturut – turut 13,91 m3 dan 3.107,98 kg, dengan persentase perbandingan volume beton 4% dan volume tulangan 3%. Perbandingan biaya kebutuhan beton dan kebutuhan tulangan metode Building Information Modelling (BIM) lebih rendah dari metode Konvensional dengan selisih biaya kebutuhan beton dan tulangan yaitu berturut – turut Rp 14.320.282,04 dan Rp 36.537.806,58, dengan persentase perbandingan biaya beton 4% dan biaya tulangan 3%. Perbandingan Rencana Anggaran Biaya (RAB) total perhitungan menggunakan metode Building Information Modelling (BIM) lebih rendah dari metode Konvensional dengan selisih yaitu Rp 50.858.088,63 (Lima Puluh Juta Delapan Ratus Lima Puluh Delapan Ribu Delapan Puluh Delapan Koma Enam Puluh Tiga Rupiah) atau selisih 3%.
TEMPO DE JEJUM PRÉ-ABATE E A INFLUÊNCIA SOBRE A QUALIDADE DE CARCAÇA DE SUÍNOS
Authors: De Witt O. , Dos Santos B. R. C. , Peripolli V. , Bianchi I. , Schwegler E. , Moreira F. 
Published: August 2024

O manejo pré-abate é imprescindível para garantir a qualidade da carne suína e o bem-estar animal. Esta revisão teve como objetivo relatar a influência do tempo de jejum pré-abate, entre 6 e 12 horas, sobre a redução do peso corporal, aspectos sanitários e qualidade da carcaça de suínos terminados. O jejum pré-abate ocorre no estágio final da fase de terminação de suínos e persiste até o momento do abate. Os animais são privados de alimentos sólidos, mas devem ter acesso ad libitum à água. Essa prática de manejo é de suma importância para o produtor, para o abatedouro, uma vez que proporciona diversos benefícios, como a economia de ração, redução da taxa de mortalidade durante o transporte, incremento na velocidade da evisceração e redução do potencial de contaminação. Além disso, reduz o volume de dejetos e melhora a padronização do rendimento de carcaça, o que contribui para a manutenção da qualidade da carne. Essas práticas de manejo pré-abate devem ser equilibradas para otimizar a segurança alimentar e assegurar a qualidade da carne, ao mesmo tempo em que se minimiza o estresse e o desconforto dos animais. É essencial seguir rigorosamente as diretrizes estabelecidas por órgãos reguladores e as evidências científicas para assegurar uma produção suína sustentável e ética. A definição precisa do período de jejum é imprescindível para garantir e promover o bem-estar animal e a obtenção de carne suína de alta qualidade. A adoção de práticas de manejo embasadas em dados científicos e regulamentações apropriadas contribui significativamente para a sustentabilidade e eficiência da indústria suinícola, beneficiando produtores, consumidores e, principalmente, os próprios suínos.
RETRACTED: Exoplanet Harmony: Confirming Kepler’s Third Law with Kepler and TESS Discoveries
Authors: Jiang Jonathan H. , Lam Jadon 
Published: August 2024

Abstract
We investigate whether the orbital periods of exoplanets discovered by the Kepler and TESS missions adhere to Kepler’s Third Law, akin to the planets in our solar system. Using data obtained from the NASA Exoplanet Archive (DOI:10.26133/NEA12) on 2024 June 24, we analyzed 2659 Kepler observations and 415 TESS observations. Our results demonstrate that the exoplanets observed by both Kepler and TESS missions follow Kepler’s law, with deviations that are within the expected range of observational uncertainties. This confirms that Kepler’s Third Law holds true for exoplanets beyond our solar system.
Developing Self-Regulated Learners in Nursing
Authors: Coffman Sherrilyn , Taber Anna 
Published: August 2024

Background:
Students who enter nursing programs without adequate study skills may be shocked when they fail their first nursing examination or assignment. If they continue to struggle, they may fail to progress to graduation or may perform poorly on their licensure examinations.

Method:
Assignments based on self-regulated learning theory can help students develop control over their learning environment, establish effective study strategies, set goals, and prevent procrastination.

Results:
Two assignments for students studying for a baccalaureate of science in nursing are presented as examples of activities that promote self-regulated behaviors: (1) Research Literature Search Assignment Strategies worksheet and (2) student-led examination reviews to prepare for an examination. Students' reactions to assignments are described.

Conclusions:

Integration of the principles of self-regulated learning can add value to active learning. Faculty with an understanding of self-regulated learning theory are better able to recognize student deficiencies and design assignments to help students succeed.

[
J Nurs Educ
. 2024;63(X):XXX–XXX.]
Technology foresight for the South African road transport sector by 2035
Authors: Rust Frederik C. , Sampson Leslie R. , Cachia Adriana A. , Verhaeghe Benoit M.J.A. , Fourie Helena S. , Smit Michelle A. , Hoffman Alwyn , Steyn Wynand J.v.d.M. , Venter Karien , Lefophane Samuel 
Published: August 2024

Background: Foresight can be used to define futuristic orientated research and development (RD) that is required to position the road transport sector for a challenging future.Objectives: To develop a set of futuristic RD projects that could be added to a balanced SANRAL RD portfolio to position SANRAL and the transport sector for the future on a 15-year horizon.Method: Inputs into and ranking of the drivers, trends and technologies that will impact the transport sector were obtained from interviews with eminent thinkers, participants in workshops and a survey leading to five potential future scenarios. Qualitative and quantitative data analysis yielded several key solutions (KSs) and key interventions (KIs) to position the sector. This was complemented with the novel use of technology trees to analyse the linkages between new and existing knowledge and to identify gaps in knowledge and subsequently the identification of key RD opportunities.Results: Through backcasting from the desired future scenario as well as using 412 stakeholder inputs, 12 KSs and 61 KIs were defined and ranked. The top 30, most futuristic KIs were analysed using 18 hierarchical technology trees to define RD opportunities.Conclusion: The analysis emphasised the importance of new technologies such as data science, machine learning, smart transport and advanced materials to position the sector.Contribution: The use of a novel, structured technology foresight approach that utilises scenario development combined with hierarchical technology trees was demonstrated. To position the road transport sector for a challenging future, 12 new thematic KSs and 61 KIs were developed.
Neurological examination of healthy term infants at ages 6 and 10 weeks in Tshwane District
Authors: Nel Marna , Feucht Ute , Mulol Helen , Eksteen Carina A. 
Published: August 2024

Background: Globally, there is a significant gap in detailed neurodevelopmental data for infants under 3 months, despite 6 weeks being identified a critical milestone for neuro-behavioural development. Normative values and optimal scores for healthy infants at 6 and 10 weeks postnatally are lacking in many settings. In South Africa, the statutory neurodevelopmental assessments at these ages exclude notable characteristics of central nervous system maturation and limit opportunities to collect data of early developmental progress.Objectives: Our study aimed to assess developmental characteristics of healthy term infants aged 6 and 10 weeks using the Hammersmith Neonatal Neurological Examination (HNNE).Method: A prospective longitudinal study was performed on 35 healthy term-born infants from low-risk pregnancies at 6 and 10 weeks’ postnatal age in the Tshwane district. The statuses of infants’ neurodevelopment in six domains were recorded using the HNNE. Optimality scores were derived from the raw scores of 34 items, using the 10th and 5th percentiles as cut-off points.Results: Evidences of neurodevelopmental advancements, particularly in posture, muscle tone and visual behaviour between 6 and 10 weeks were illustrated, and total examination optimality scores of 29.5 in 91% and 31.5 in 94% of infants were recorded at 6 and 10 weeks, respectively.Conclusion: This article provides data on the neurodevelopment characteristics of infants at and between 6- and 10-weeks post term ages.Clinical Implications: The findings support the viewpoint to identify important milestone characteristics during early screening.
The Association between Cardiorespiratory Fitness and Obesity Predictors in Healthy Young Adults: An Observational Study
Authors: Buttar Karampreet Kour , Kacker Sudhanshu , Saboo Neha 
Published: August 2024

Abstract

Introduction:
Obesity lowers cardio respitaory fitness (CRF) or maximal oxygen uptake (VO2 max) by exhausting the circulatory system and working muscles. There has not been enough research done on the Indian population to determine the relationship between cardiorespiratory fitness and obesity predictors including body mass index (BMI), body fat percentage, and body surface area (BSA) in a single plot. Therefore, this study aimed to examine the associations between cardiorespiratory fitness and body fat parameters in young adults.

Materials and Methods:
Four hundred and nineteen respondents from the RUHS-College of Medical Sciences, Jaipur, India, were screened. A Harpenden skinfold caliper was used to determine their body fat percentage, after which a gas analyzer was used to determine their VO2 max. BSA (m2) was calculated using the Dubois equation. The “Pearson correlation coefficient” and “Student’s t-test” were applied for the statistical analysis.

Results:
The relationship between VO2 max with BSA, body fat percentage, and BMI was inverse. The correlation (r = −0.46) between body fat percentage and VO2 max was greater than that of BMI or BSA (r = −0.09 and r = −0.21, respectively). Both genders with normal BMI had the greatest VO2 max (47.22 ± 6.94; 37.75 ± 4.88 ml/kg/min). The maximum VO2 max (46.726.81; 38.744.08 ml/kg/min) is found in both men and women who fall into the fitness group of body fat percentage.

Conclusion:
Increased BMI, body fat percentage, and BSA are associated with decreased levels of V̇O2 max. Compared to BMI and BSA, body fat percentage is a better indicator of obesity. Thus, encouraging people to reduce their body fat percentage and obesity would improve their cardiorespiratory fitness.
Von Willebrand factor levels in healthy blood donors and their association with blood group
Authors: Agrawal Nikita , Pahuja Sangeeta , Sharma Sunita 
Published: August 2024

BACKGROUND:
von Willebrand disease is a common inherited bleeding disorder caused by the deficiency of von Willebrand factor (vWF).[1] The levels of vWF depend on several factors, including exercise, hormones, and ABO blood type.[2] This study was planned to evaluate plasma vWF levels and factor VIII (fVIII) levels in healthy blood donors and its association with the ABO blood group.

AIMS:
The aim of this study was to evaluate plasma vWF levels and fVIII levels in healthy donors and its association with the ABO blood group.

METHODS:
This study was done in 2016 healthy adult blood donors. Complete history and relevant examination were done along with ABO and Rh (D) blood group typing, complete blood count, prothrombin time, activated partial thromboplastin time, vWF antigen (Ag) level, fVIII coagulant assay, and other tests for hemostasis.

STATISTICAL ANALYSIS USED:
Data were expressed in proportions and mean, median, and standard deviation, respectively. An appropriate test of significance was applied. P < 0.05 was considered statistically significant.

RESULTS AND CONCLUSIONS:
vWF level of donors ranged from 24 to 186 IU/dL with a mean of 96.31 IU/dL. Low vWF Ag level (below 50 IU/dl) was found in 2.5% of donors while 0.1% (2/2016) had level <30 IU/dL. O Rh (D)-positive blood group donors had the lowest vWF level (87.85 IU/dL), while ARh (D)-negative donors had the highest vWF level (117.27 IU/dL). fVIII level of the donor population ranged from 22% to 174%, with a mean of 98.82%. About 2.48% of donors had fVIII levels below 50%. There was a statistically significant correlation between fVIII level and vWF level (P < 0.001).
A conservative approach in finding compatible blood for a patient with sickle cell disease having multiple alloantibodies
Authors: Joshi Sanmukh Ratilal , Vekariya Mayuri M. , Rajapara Manisha M. 
Published: August 2024

BACKGROUND:
Sickle cell disease (SCD) patients may develop multiple alloantibodies that pose problem in finding compatible blood for transfusion and require crossmatching with large number of blood.

AIM:
The aim of the present study was to find compatible blood with reduced cost by adopting a conservative approach.

MATERIALS AND METHODS:
A step-by-step approach using tube technique, antibodies in original serum, and the saved test supernatant (TS) in search of compatible blood for transfusion purposes.

RESULTS:
32 years SCD patient grouped A with multiple antibodies required transfusion. A total of 641 red blood cell (RBC) units of groups A and O were crossmatched using serum and the TS by tube method. Of 138 units tested using the serum at 4°C, 124 units showed direct agglutination in the saline phase and the remaining 14 units were processed through low ionic strength solution (LISS)-IAT, of which 2 units were compatible even by the gel-IgG-card method. The TS, saved from the tests on serum, was used in an identical manner as that of the serum to screen additional 503 units by saline tube method at 4°C units showed direct agglutination of the RBCs of 428 units, hence were removed from inventory for this patient. The remaining 75 units were tested by the LISS-IAT-tube method at 37°C, of which 8 units were found compatible but only 2 units were clear compatible by the gel-IgG-card method. As such, 4 units compatible by the sensitive gel-IgG-card method were issued for transfusion purposes.

CONCLUSION:
The new approach on using the saved TS consumed less of the patient's blood specimen, and the use of the tube method in screening and eliminating a large chunk of incompatible blood units has proved economical if compared with the use of the only gel-IgG-cards device in the entire maneuvering.
Exploring therapeutic plasma exchange as a progressive treatment modality for neurological disorders: Insights from a tertiary care hospital in Northwestern India over 3 years
Authors: Yadav Anshika , Sharma Smriti , Gupta Gajendra Nath 
Published: August 2024

Abstract:

BACKGROUND:
Neurological disorders with autoimmune or inflammatory etiology pose significant challenges in terms of treatment. Therapeutic plasma exchange (TPE) has emerged as a promising adjunctive therapy for managing these conditions by removing pathogenic autoantibodies, immune complexes, and proinflammatory mediators. However, the experience with TPE in neurological disorders in the northwestern part of India is limited.

METHODOLOGY:
This retrospective study analyzed the medical records of patients who underwent TPE for neurological disorders over a 3-year period at a tertiary care hospital. Patient demographics, clinical diagnoses, TPE protocols, and adverse events were collected and analyzed. Descriptive statistics were used to summarize the data.

RESULTS:
A total of 26 patients (14 males, 11 females) underwent 111 TPE procedures during the study period. The most common clinical diagnoses were generalized dystonia, Guillain–Barré syndrome, myasthenia gravis, and chronic inflammatory demyelinating polyneuropathy. TPE protocols involved exchanging one plasma volume every alternate day, with replacement solutions including fresh-frozen plasma (FFP), albumin, or a combination of FFP and albumin. The majority of patients showed positive clinical improvement measures, indicating the efficacy of TPE in halting disease progression and ameliorating symptoms. Adverse events were reported in seven procedures but were successfully managed.

CONCLUSION:
This study demonstrates the effectiveness and safety of TPE in the management of autoimmune or inflammatory neurological disorders in the northwestern part of India. TPE showed positive clinical improvement measures and a favorable safety profile. These findings contribute to the growing recognition of TPE as an emerging therapeutic modality in the field of neurology. Further research and prospective studies are needed to optimize TPE’s use, including patient selection, treatment protocols, and long-term outcomes in this population.
Aliquoting of red blood cells for transfusion in pediatrics
Authors: Arora Satyam , Dua Seema 
Published: August 2024

Abstract:

BACKGROUND AND OBJECTIVES:
Small-volume transfusions of red blood cell (RBC) aliquots are a very common practice across the world; however, there is a lack of data on various strategies of aliquot preparation and their utilization.

MATERIALS AND METHODS:
A descriptive retrospective study, from January 1, 2022, to December 31, 2022, was conducted at the blood center of a government-owned children’s teaching hospital in India. The study aimed to analyze the practices of preparation, utilization, and practice of various number of RBC aliquots prepared.

RESULTS:
A total of 222 RBC units were divided into 591 aliquots with a mean volume of 98.4 ± 32.3 ml (median 100 ml; 2.66 aliquots per RBC unit). Out of these 222 RBC units, 81 were split into two aliquots (Group 1); 141 RBC units were split into three (Group 2) and 6 units were prepared into four aliquots (Group 3). A total of 577 patients (359 male; 218 female) were transfused (2.3% of aliquots discarded due to expiry). 85.2% (492 of 577) of children who were transfused these aliquots were <2 years of age. The majority of RBC aliquots (>80%) were prescribed by the department of pediatric medicine (35%). Groups 2 and 3 were aliquoted from significantly fresh RBC units (mother unit) compared to aliquots prepared in Group 1.

CONCLUSION:
Our data show a high utilization rate (97.3%) of RBC aliquots at our institute. Uniform practices in aliquoting practices will help us harmonize the data as well as establish best practices in neonatal and pediatric transfusion practices.