bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mechanism of healing, strength, and durability concepts of bacteria concrete - a review
Authors: Mithanthaya I R , Shet Vinayak B , Mokshitha M 
Published: August 2024

Abstract
Research work is going on to explore the concept of self-healing concrete. Outcome of the investigation reveals potential of bacteria concrete. Self-healing capacity imparted to the concrete by incorporating bacteria. Traditional methods reported in the literature such as epoxy injection, grouting, drilling, and plugging and gravity filling method have environmental impact, require more maintenance and are time consuming. The self-healing mechanism can be a better alternative to compensate these defects due to ecofriendly nature. Self-healing mechanism involves the production of CaCO3 precipitate deposites in crack region. Review paper focused on self-healing efficiency, water permeability, chloride penetration, compressive strength, flexural strength and recovery of water tightness, percentage weight loss of both conventional and bacterial concrete. For good environment tomorrow and better sustainability, self-healing conceptin concrete structure contributes promising technology.
“Karmik”- A Tool to Bridge Client and Migrant Construction Labors Amid Pandemic.
Authors: Acharya Harish , Kalathur Abharan , Manjunatha M 
Published: August 2024

Abstract
Migrant labors migrate to Udupi for socio-economic reasons. Many of them can’t get job according to their skills due to lack of information about requirements in construction field. This will keep them unemployed. In other word client also face same problem, they can’t find labors according to their requirements. To bridge this gap and to develop better connection between client and labor we need a platform. Our idea is to develop a mobile application which includes data of construction labor such as his/her name, skills, and phone number. By surveying, collecting labor data and later by compiling it as a database we build a mobile application which will directly affect in improvement of construction labor status in and around Udupi region. Survey-based data in the selection process. Data collected at these hotspots would be categorized into geographical coverage, age, experience, and type of work. These statistics arrived from the raw data collected verbally from labors across these hotspots will be compiled and analysed to give us current availability of labors.
Integrating Dimensions in Predictive Risk Models for Construction Projects
Authors: Avanthika  , Naik Pushparaj A. 
Published: August 2024

Abstract
This review explores the evolution of predictive risk models in construction, emphasizing the integration of key dimensions—quality, safety, schedule delay, cost overrun, and environmental risk. Synthesizing diverse literature, it highlights findings, methodologies, and implications. From a historical perspective, it outlines criteria and search strategies, addressing limitations. Thematic sections delve into individual risk dimensions, and cross-theme analysis identifies overarching trends. Methodological approaches are scrutinized, challenges and controversies are discussed, and future directions suggest areas for exploration. In conclusion, the paper advances holistic risk management, aiding researchers, practitioners, and stakeholders in construction project risk assessment.
Durability Studies and Stress Strain Characteristics of hooked end steel fiber reinforced ambient cured geopolymer concrete
Authors: Laxmi G , Patil S G 
Published: August 2024

Abstract
For conventional concrete, the use of fibers has proven to improve the strength properties of the material. However, in the case of ambient cured geopolymer concrete, there are limited studies that explore the application of fibers, in particular, the use of hooked end steel fibers. Further, it is important to study the durability properties of geopolymer concrete with fibers, since it will influence the service life of the structures in practice. Therefore, in the present study, fiber-reinforced geopolymer concrete was synthesized using fly ash, GGBS, hooked end steel fibers, and alkaline solution made with Na2SiO3 and NaOH. The percentage of steel fibers varied in the range of 0.5% to 2% with an increment of 0.5% by volume fraction of the binder. The precursor materials were characterized using techniques such as X-ray fluorescence (XRF), X-ray diffraction (XRD), and scanning electron microscope (SEM). Durability studies like water absorption, drying shrinkage, sulphate attack were studied. In addition, the elastic constants were determined through stress strain behaviour of geopolymer concrete in uniaxial compression. The results of the experimental study showed that the addition of hooked end steel fibers influences the strength of geopolymer concrete up to an optimal percentage, which was found to be 1%. Furthermore, in terms of durability properties, the addition of fibers exhibited better results in terms of resistance to water absorption and chemical attack, and this was validated by the microstructural studies, where the specimens with hooked end steel fibers revealed much denser hardened geopolymer matrix when compared to the mixes without fibers.
Performance Study on Laterite Block with Perlite
Authors: Shenoy Sundip , Mahshook Abdul , Kumar Bhat Arun , Kabeer Ahmed Shaik 
Published: August 2024

Abstract
The term “perlite” refers to an amorphous volcanic silicate/alumina rock that can expand at temperatures between 900 and 1200 ∼C when heated fast. Because perlite is so versatile, it can be applied in a variety of sectors, including construction, horticulture, petrochemical, and industrial. An item that is used in the construction sector is expanded perlite (EP). It can be used as an input for geopolymers or mixed with aggregate or cement to create conventional cementitious materials. EP offers low density, effective thermal and acoustic insulation, and exceptional fire resistance for buildings. Perlite appears to be a necessary material as a result. The author of this article examines the effects of EP, a chemical used in building materials, on the properties of geopolymers, different types of binder, and regular cementitious materials, both in their fresh and hardened states.
The usefulness of using perlite-reinforced laterite blocks as a sustainable building material is investigated in this work. We investigate this composite’s potential for usage in building applications by thoroughly examining its mechanical and thermal properties. The results provide insight into how robust and eco-friendly construction practices could be supported by increasing structural strength and thermal efficiency.
An Experimental Study on The Effect of Chemical Composition on The Strength Behaviour of Geopolymer Mortar
Authors: Brunda B N , Amar R , Chethan B A 
Published: August 2024

Abstract
Sustainable development in the construction industry aims to improve the lifetime standards of present and future generations. Among industrial by-products, Ground Granulated blast Furnace Slag (GGBS) powder is employed as a cementitious material. This work investigates the properties of geopolymer binders prepared using the GGBS without conventional cement. The individual properties of the Geopolymer mortar (GPM) samples such as compressive strength and chemical composition were evaluated as per relevant IS Standards. Cubes of size (70.6×70.6×70.6) mm were cast and cured at ambient conditions for molarity 8M, 10M, and 12M with different fine aggregates, i.e., River sand, M-Sand, and GGBS. Compressive strength for 3, 7, and 28 days was evaluated. The results exhibit higher improvement in strength for 12M GPM’s with higher strength for river sand-based mixes. The chemical composition of GPM samples after 28 days of curing is determined. Essential chemical constituents such as SiO2 in 12M GPM’s considerably increased compared to 8M and 10M. The water absorption rate of samples with M-sand is greatly lowered with increasing molarity compared to those with river sand. The dry density of samples with M-sand exhibited higher improvement with increased molarity than those with river sand.
Comparative Seismic Analysis of Regular and Irregular Multistorey Structures with and without Bracings and Shear wall
Authors: Shamana B S , Manu K C , Madhushree C 
Published: August 2024

Abstract
Seismic effect is one of the main factors which has to be considered during the design of structure. Earthquake is one of the supreme hazards for living and assets on earth. It is a natural phenomenon, occurring with uncertainties as a result of sudden release of energy within earth crust in the form of seismic waves. As the earthquake forces affects the stability of the building and about 60% of region in our country is under the influence of seismic forces, the buildings are provided with alternatives to withstand the horizontal forces and to increase the strength, stability and stiffness. Present paper investigates the performance of different structures provided with seismic resisting components. In this paper Shear walls and bracings are incorporated to make the structure moment resisting frame. A comparative seismic analysis of high-rise structures with and without shear walls and bracings is included in this discussion which is done using ETABS 2019 software by Response Spectrum Analysis. The parameters considered for analysis are natural frequency, natural time period, base shear, story stiffness, story displacement and story drift. in constructing both.
Once Upon a Time in Facilities Management
Authors: McCarroll Patricia , Hassard John 
Published: August 2024

Abstract
This book explores the storied spaces and narrative archetypes of a secondary business service, using facilities management (FM) as an example of non-core and increasingly outsourced organizational activities. The centrepiece is the development of artificial folklore, a research approach combining organizational analysis, storytelling, and folklore for interpretive purposes. An in-depth exploration of FM is developed; one exploring people, place, and process in a project revealing elements of organizational liminality as well as professional enchantment. This leads to concentration on the storytelling nature of secondary services, specifically utilizing the genre of fairytales to investigate narrative patterns within FM’s cultural environment. In the process, three modes of FM delivery are identified: consultancy provision, service provision, and in-house provision; modes which are narratively demarcated as professionals tell both deconstructed and reconstructed tales about their work. What is revealed is a recognized understanding across the three provider groups of their role as the ‘necessary evil’ of business organization, and notably as represented—in folkloric terms—by the shadow archetype. Ultimately, the artificial folklore approach developed in this book produces ghostwritten tales for each of the main FM provider streams; tales which reflect symbolically, the consultancy provider’s Hansel and Gretel, the service provider’s Goldilocks, and the in-house provider’s Cinderella organizational motifs. The outcome of this inquiry is a new diagnostic approach to the study of management, work, and organization—one linking elements of social theory, narrative analysis, and the business imaginary.
Our Moral Judgements Are All Wrong
Authors: Lenman James 
Published: August 2024

Abstract
Error theorists claim that moral judgements are all false but suppose that we have a morally neutral understanding of practical reason that can survive the wholesale rejection of morality and which we can employ in evaluating the options—abolitionism, fictionalism, etc.—for what we might, after embracing error theory, go on to do. This claim is contested. Many error theorists argue further that after we cease to believe in morality we still have abundant reason to continue to treat each other decently by adopting some kind of fiction which we make-believe is true. We do indeed have abundant reasons to treat each other decently but these are just the moral reasons the error theorist denies. We can make excellent sense of moral reasons along constructive expressivist lines explained in this book without resorting to the ropey metaphysics the error theorist agrees with the robust realist in taking morality to presuppose. It is robust realism, not morality, we need to reject. Constructive expressivism by taming the mystery that can seem to attach to such notions as irreducible normativity and external reasons robs error theory of its philosophical motivation and rescues morality from vulnerability to sceptical attack.
Targeting NUF2 suppresses gastric cancer progression through G2/M phase arrest and apoptosis induction
Authors: Long Bo , Zhou Huinian , Xiao Lixia , Jiang Xiangyan , Li Jian , Ma Zhijian , He Na , Xin Wei , Zhang Boya , Zhu Xiaoqin , Yu Zeyuan , Jiao Zuoyi 
Published: August 2024

Abstract

Background:
Gastric cancer (GC), a malignant tumor with poor prognosis, is one of the leading causes of cancer-related deaths worldwide; consequently, identifying novel therapeutic targets is crucial for its corresponding treatment. NUF2, a component of the NDC80 kinetochore complex, promotes cancer progression in multiple malignancies. Therefore, this study aimed to explore the potential of NUF2 as a therapeutic target to inhibit GC progression.

Methods:
Clinical samples were obtained from patients who underwent radical resection of GC at Lanzhou University Second Hospital from 2016 to 2021. Cell count assays, colony formation assays, and cell-derived xenotransplantation (CDX) models were used to determine the effects of NUF2 on GC progression. Flow cytometry was used to detect the effect of NUF2 or quercetin on cell cycle progression and apoptosis. A live-cell time-lapse imaging assay was performed to determine the effect of NUF2 on the regulation of mitotic progression. Transcriptomics was used to investigate the NUF2-associated molecular mechanisms. Virtual docking and microscale thermophoresis were used to identify NUF2 inhibitors. Finally, CDX, organoid, and patient-derived xenograft (PDX) models were used to examine the efficacy of the NUF2 inhibitor in GC.

Results:

NUF2 expression was significantly increased in GC and was negatively correlated with prognosis. The deletion of NUF2 suppressed GC progression both in vivo and in vitro. NUF2 significantly regulated the mitogen-activated protein kinase (MAPK) pathway, promoted G2/M phase transition, and inhibited apoptosis in GC cells. Additionally, quercetin was identified as a selective NUF2 inhibitor with low toxicity that significantly suppressed tumor growth in GC cells, organoids, CDX, and PDX models.

Conclusions:
Collectively, NUF2-mediated G2/M phase transition and apoptosis inhibition promoted GC progression; additionally, NUF2 inhibitors exhibited potent anti-GC activity. This study provides a new strategy for targeting NUF2 to suppress GC progression in clinical settings.
Top 100 cited articles related to EUS: A bibliometric analysis
Authors: Li Tongxin , Kang Chenxi , Ren Gui , Lv Yong , Luo Hui , Kang Xiaoyu , Liang Shuhui , Wang Xiangping , Pan Yanglin 
Published: August 2024

ABSTRACT

Background and Objectives
Citation analysis is a fundamental method in bibliometrics for quantifying the impact and contribution of articles on a specific biomedical field. The purpose of our study was to identify and analyze the top 100 cited articles in the field of EUS.

Methods
All published articles in the field of EUS were searched by using “endoscopic ultrasound” and its synonyms as the search terms without time limit. The Institute for Scientific Information Web of Science Core database was searched to determine the citations. The top 100 cited articles were identified and further evaluated for characteristics including publication year, authors, journals, impact factor, countries, institutions, article type, topic term, and evidence grade, among others.

Results
A total of 430 articles were cited more than 100 times. The 100 most-cited articles were published between 1988 and 2018, and the medium citation was 240.5 (104.25). The top 100 cited articles mainly focused on diagnostic performance (80%) and interventional therapy (20%). The numbers of articles studying the diagnostic accuracy of FNA (n = 29) and tumor diagnosis (n = 29) were the highest among research articles on FNA and EUS of diagnostic categories, and EUS transluminal drainage (n = 14) was the most frequently used EUS technique for therapy. The focus of the majority of the articles was on diseases of pancreas (n = 55), and among the 55 articles related to pancreatic diseases, pancreatic cancer (n = 17) and solid pancreatic masses (n = 13) were the most researched topics. In addition, we found that the proportions of diagnostic and treatment-related articles at different time periods have statistical significance (P < 0.05).

Conclusions
Our analysis provides an insight into the top 100 articles in the field of EUS, revealing EUS-guided FNA, tumor staging, and transluminal drainage as the major advances in the past 35 years. Pancreatic diseases were the most researched, especially pancreatic cancer or solid pancreatic masses. Our research has found that the number of articles on the application of EUS treatment has significantly increased.
“Successful Living” Among Adolescents With HIV in Sub-Saharan Africa: An Evolutionary Concept Analysis
Authors: Kayiranga Dieudonne , Mukamana Donatilla , Gishoma Darius , Relf Michael V. 
Published: August 2024

Abstract
The concept of successful living in the context of adolescents with HIV lacks clarity and is unexplored. Without a common understanding of successful living among adolescents with HIV (AWH) in Sub-Saharan Africa (SSA), health care interventions focusing on this population may continue to fall short, resulting in avoidable morbidity and mortality. Therefore, this analysis used Rodgers Evolutionary Concept Analysis method to identify attributes, antecedents, consequences, and related concepts of successful living among AWH in SSA. Health care interventions are encouraged to promote successful living among AWH to achieve behavioral and clinical outcomes.
Elevated 131I Activity in Adrenal Cyst in a Patient With Thyroid Cancer
Authors: Liu Wei , Yang Xiao , Gong Weidong , Wang Jianqiang , Fan Xueyuan 
Published: August 2024

Abstract
A 23-year-old man with papillary thyroid cancer underwent radioiodine (131I) treatment following total thyroidectomy and node dissection. Posttreatment 131I SPECT/CT images revealed an additional focus of increased 131I activity in the left adrenal gland, raising suspicion for possible adrenal metastasis. Ultimately, pathological examination confirmed the diagnosis of an adrenal cyst.
NINJ1: A Novel Sepsis Severity and Mortality Biomarker
Authors: Wu Yongbin , Li Tao , Tan Sichuang , Song Ruoyu , Song Kaiyuan , Zhou Jiankang , Xiao Xianzhong , Wang Kangkai , Zhang Huali , Tan Sipin 
Published: August 2024

Abstract

Background
Multiple cell death modalities are implicated in sepsis pathobiology. However, the clinical relevance of NINJ1, a key mediator of plasma membrane rupture during lytic cell death, in sepsis progression and outcomes has remained poorly explored.

Methods
Circulating NINJ1 levels were measured in 116 septic ICU patients, 16 non-septic ICU controls, and 16 healthy controls. Comparative analysis of serum NINJ1 across these groups was performed. Correlations between NINJ1 and clinical disease severity scores (SOFA, APACHE II) as well as laboratory parameters were examined in the sepsis cohort. Furthermore, we assessed the prognostic performance of NINJ1 for predicting 28-day mortality in septic patients using receiver operating characteristic (ROC) analyses.

Results
Circulating NINJ1 levels were elevated in septic patients and positively correlated with sepsis severity scores. NINJ1 also showed positive correlations with liver injury markers (AST/ALT) and coagulation parameters (D-dimer, APTT, PT, TT) in sepsis. Further analysis using the ISTH overt DIC scoring system revealed an association between NINJ1 and sepsis-induced coagulopathy.
ROC analysis demonstrated NINJ1 outperformed traditional inflammatory biomarkers PCT and CRP in predicting 28-day sepsis mortality, although its prognostic accuracy was lower than SOFA and APACHE II scores. Combining NINJ1 with SOFA improved mortality prediction from an AUC of 0.6843 to 0.773.

Conclusions
Circulating NINJ1 serves as a novel sepsis biomarker indicative of disease severity, coagulopathy and mortality risk, and its integration with SOFA and APACHE II scores substantially enhances prognostic risk stratification. These findings highlight the prospective clinical utility of NINJ1 for sepsis prognostication and monitoring, warranting further validation studies to facilitate implementation.
Inhibition of Rho Kinase or Myosin-light chain kinase decreases Dengue virus replication in endothelial cells
Authors: Nichols Gena , Spengler Andrea , Voss Thomas G. 
Published: August 2024

Dengue virus (DV), a member of the Flaviviridae family, has been demonstrated to induce changes to the actin cytoskeleton to promote efficient viral entry and replication. These cytoskeletal alterations continue throughout infection, and disruption of the cytoskeleton has been shown to decrease the release of infectious virions. However, few studies have assessed the contribution of actin alterations to Dengue-induced vascular leak in endothelial cells. A number of cellular kinases control the assembly and rearrangement of actin filaments, including Rho-activated kinase (ROK) and Myosin Light Chain kinase (MLCK). To determine whether the observed changes to the actin cytoskeleton during Dengue viral infection contribute to the loss of endothelial cell barrier function, the roles of the cellular kinases ROK and MLCK were evaluated during DV infection. While kinase inhibition did not prevent virus-induced changes in monolayer permeability, specific inhibition of either kinase resulted in a significant decrease in virus yield indicating that ROK/MLCK-mediated cytoskeletal alterations play a role in virus replication and biogenesis that do not affect vascular integrity in Dengue virus infection in vitro. Further investigation revealed that ROK or MLCK inhibition decreased virus yield, but only MLCK inhibition decreased viral protein synthesis and genome replication. Taken together, these results identify a role for both ROK and MLCK activity in the efficient replication of Dengue virus in endothelial cells, potentially affecting the assembly or budding of mature Dengue virions.