bluuebunny/crossref_metadata_2025_split huggingface dataset:
La représentation de la violence adolescente... dans la culture contemporaine
Authors: Bergami G. Barbosa Pablo 
Published: November 2014

Cet article analyse la place de la notion d’une « violence des adolescents » dans la culture contemporaine, mettant en évidence ses surdéterminations idéologiques et psychiques. Un rappel de certains repères théoriques concernant les mécanismes psychiques impliqués dans le processus d’adolescence permet de souligner l’importance de la sublimation comme destin pulsionnel privilégié permettant à l’adolescent de se servir de la « violence pulsionnelle » qui l’assaille. Une observation des pratiques culturelles contemporaines sert alors à révéler les mécanismes culturels propres à notre époque favorisant la constitution de destins sublimatoires pour l’agression et la violence. La contemporanéité est ainsi caractérisée comme une époque dans laquelle une réduction effective de la violence se conjugue avec une perception sociale de celle-ci comme en constante augmentation. Les conséquences d’un tel état de choses sur la clinique de la « violence adolescente » sont abordées, soulignant le besoin de comprendre l’acte violent dans sa dimension signifiante, comme tentative (ratée) de symboliser les conflits liés aux processus d’adolescence.
La violente recherche d'une inscription familiale
Authors: Otero Rossi Maria , Payan Ségolène 
Published: November 2014

Raphaël, trois ans, est né grâce à une fiv . Malgré un ardent désir d’enfant qui a amené ses parents à avoir recours à une procréation médicalement assistée, cette intrusion de la technique dans l’intimité de ce couple a généré des difficultés pour le père à inscrire ce garçon dans la lignée familiale. Se montrant violent à l’égard de « son » fils, ce dernier reproduit une certaine forme de violence qui n’a toutefois pas la même signification. Les interrogations sur l’impact possible de la pma sur la vision de la cellule familiale et sur celui du discours sociétal sur la « violence » d’un jeune enfant nous amènent à revisiter les concepts de violence et d’agressivité. En conclusion, parler d’enfant violent nous apparaît comme une provocation, liée à un malaise dans notre culture.
Processus d'élaboration d'hypothèses... dans un cas d'enfant déclaré « violent »
Authors: Essadek Aziz 
Published: November 2014

L’objet de ce travail est de montrer l’élaboration des hypothèses que l’on peut faire lors d’un accompagnement psychologique d’enfant et qui évoluent au fur et à mesure de la rencontre clinique. Dans le cadre de notre étude, les hypothèses ont été proposées à partir de ce que l’enfant, dit « violent », a pu apporter en entretien. Par ailleurs, ont également été mis en évidence les différents mécanismes de défense mis en place par l’enfant pour lutter contre la « crainte de l’effondrement » en réponse à un environnement insuffisamment bon. Ici, la crainte de l’effondrement a pris la forme d’une répétition de la rupture du lien avec la mère.
Vers un accompagnement des cadres dans l'adoption d'une vision moderne de la gestion : le rôle de la direction des ressources humaines
Authors: Côté Marie , Harvey Jean-François , Picard Amélie 
Published: November 2014

Les différentes normes et approches de gestion auxquelles les établissements de santé et de services sociaux choisissent d’adhérer amènent leur lot de défis transformationnels : élargir sa vision de l’équipe ; penser globalement et de façon plus durable ; adopter des modes de travail collaboratif ; remettre en question les façons de faire et de penser ; mesurer avec rigueur, s’évaluer et se dépasser ; et exercer un leadership de proximité. L’impact des défis transformationnels dépasse le rôle et les responsabilités des cadres et se reflète dans la philosophie de gestion que ceux-ci adoptent. L’étude qualitative présentée dans cet article s’intéresse aux besoins des cadres face aux défis susmentionnés. Puis, en s’appuyant sur les travaux d’Ulrich, elle permet de mettre en lumière comment la direction des ressources humaines peut accompagner les cadres dans leur démarche. L’article se termine par une réflexion sur les axes d’intervention que peut mobiliser la direction des ressources humaines afin de soutenir les établissements dans leur démarche de transformation organisationnelle.
B Cell–Intrinsic MyD88 Signaling Is Essential for IgE Responses in Lungs Exposed to Pollen Allergens
Authors: Matsushita Kazufumi , Yoshimoto Tomohiro 
Published: November 2014

Abstract
Allergen-specific IgE is linked to asthma pathogenesis, but the underlying mechanisms of IgE production in response to allergen exposure are poorly understood. In this article, we show that B cell–intrinsic MyD88 is essential for IgE/IgG1 production evoked by ragweed pollen instilled into lungs. MyD88-deficient mice showed defective IgE/IgG1 production and germinal center responses to lung instillation of ragweed pollen. However, MyD88 was dispensable for dendritic cell activation and Th2 cell development. B cell–specific deletion of MyD88 replicated the defective Ab production observed in MyD88-deficient mice. Although ragweed pollen contains TLR ligands, TLR2/4/9-deficient mice developed normal allergic responses to ragweed pollen. However, anti–IL-1R1 Ab-treated mice and IL-18–deficient mice showed decreased IgE/IgG1 production with normal Th2 development. Furthermore, B cell–specific MyD88-deficient mice showed reduced IgE/IgG1 production in response to lung instillation of OVA together with IL-1α, IL-1β, or IL-18. Thus, pollen instillation into lungs induces IL-1α/β and IL-18 production, which activates B cell–intrinsic MyD88 signaling to promote germinal center responses and IgE/IgG1 production.
Purpose in life and its association with stress among persons living in a semi-urban area of Tamil Nadu
Authors: Subramaniyan R , Veliah G , Gopichandran V 
Published: November 2014

Background:
Purpose in life (PIL) is defined as the question concerning the significance or importance of life or one's existence. PIL is closely associated with spirituality and, hence, is an important determinant of health. This, in turn, leads to lower stress response and good mental health.

Objectives:
To assess the PIL and perceived psychosocial stress and to develop a conceptual understanding of the relation between the two.

Materials and Methods:
A questionnaire was developed to understand the PIL in the cultural context of semi-urban Tamil Nadu. Its internal consistency was checked and it was administered to 227 conveniently selected individuals between 15 and 70 years of age.

Results:
The questionnaire on PIL developed for this study had an acceptable internal consistency with a Cronbach's alpha of 0.883. Some common purposes in life mentioned by the people were recognition and acknowledgment for their roles and responsibilities, to be a part of a society that is higher class than their current frame, acceptance by people in society, to show people who disagree with them that they are wrong, to be treated with respect, to be known as a person with integrity, love for others, to be beneficial to others at the cost of themselves, to bring equity in the society, and to help others. It was also found that adherence to social norms as a PIL was associated with lower perceived stress.

Conclusion:
This study provides a conceptual understanding on the purposes in people's lives in the context of semi-urban Tamil Nadu and their association with perceived psychosocial stress.
Prevalence and genotypic relatedness of methicillin resistant Staphylococcus aureus in a tertiary care hospital
Authors: Fomda BA , Thokar MA , Bashir G , Khan A , Kour A , Zahoor D , Ray P 
Published: November 2014

Background:
Methicillin-resistant Staphylococcus aureus (MRSA) is the most common multidrug-resistant pathogen causing nosocomial infections across the world. MRSA is not only associated with significant mortality and morbidity but also places a large economic strain on our health care system. MRSA isolates are also typically resistant to multiple, non-β-lactam antibiotics. We conducted a prospective study in a tertiary care hospital, to determine the prevalence of MRSA and to establish the clonal distribution of MRSA isolates recovered from various clinical specimens.

Materials and Methods:
Clinical samples were cultured and S. aureus was identified as per standard microbiological procedures. Susceptibility testing was done by agar disk diffusion and minimum inhibitory concentration (MIC) method as recommended by CLSI. Methicillin resistance was detected by phenotypic methods namely, oxacillin disc diffusion (ODD), minimum inhibitory concentration (MIC) of oxacillin, cefoxitin disk diffusion (CDD), and MIC of cefoxitin. Amplification of mecA gene by PCR was used as gold standard for detection of methicillin resistance. Pulsed field gel electrophoresis (PFGE) typing was performed for MRSA isolates.

Results:
Out of 390 S. aureus isolates, 154 (39.48%) isolates were MRSA and 236 (60.51%) isolates were MSSA. Penicillin was the least effective antibacterial drug against the hospital associated S. aureus isolates with 85.64% resistance rate. All the isolates were susceptible to vancomycin. The MRSA showed a high level of resistance to all antimicrobials in general in comparison to the MSSA and the difference was statistically significant (P < 0.05). Multiplex PCR performed for all strains showed amplification of both the mecA and nucA genes in MRSA strains whereas MSSA strains showed amplification of only nucA gene. PFGE of these isolates showed 10 different patterns.

Conclusion:
Prevalence of MRSA in our hospital was 39.48%. Most of these isolates were resistant to erythromycin, clindamycin, cotrimoxazole, and ciprofloxacin, whereas high sensitivity was seen to vancomycin followed by gentamicin. CDD and MIC for cefoxitin showed 100% sensitivity, specificity, PPV and NPV as compared to PCR for mecA gene. In maximum number of isolates PFGE type A pattern was seen suggesting clonal relatedness.
Application study of 640-slice computed tomography low dose coronary angiography
Authors: Lei Ziqiao , Han Ping , Xu Haibo , Yu Jianming 
Published: November 2014

ABSTRACT

Objective:
The aim was to explore image quality and radiation dose in patients with different heart rates in 640-slice volume computed tomography (CT) coronary angiography by using tube voltage of 100 kV.

Materials and Methods:
The 220 consecutive patients clinically suspected or confirmed of coronary artery disease were divided into three groups: 67 cases in 1 beat group (heart rate <65 bpm); 134 cases in 2 beats group (65 bpm ≤heart rate <80 bpm); 19 cases in 3 beats group (heart rate >80 bpm). When scanning was completed, the best phase for coronary arteries would be chosen. Various postprocessing reconstructions of coronary arteries and branches, such as volume reconstruction (VR), maximum density projection, multiplanar reconstruction, curved surface reconstruction, were used. We classified image quality and made statistical analysis according to 4-grades method. We also compared scalability of coronary arterial segments and radiation doses between the groups.

Results:
There were no significant differences in the scalability of coronary arterial segments between the groups. Effective radiation doses of the three groups were (2.5±0.8) mSv, (8.4±3.1) mSv and (11.2±3.8)mSv. The radiation doses between the groups showed statistical difference (P < 0.05).

Conclusion:
640-slice volume CT can be adapted to changes during heart rate, and ensure the image quality under the condition of 100 kV, and radiation doses were significantly reduced in patients with heart rate <65 bpm.
Topical Nitroglycerin: A New and Safe Treatment Option for Osteoporosis
Authors: Agarwal Ayush , Singh Omkar , Agrawal Prabhat 
Published: November 2014

ABSTRACT
Osteoporosis is a progressive bone disease characterized by a decrease in the bone mass and density, which can lead to an increased risk of fracture. Multiple treatments have been formulated for it like calcium, vitamin D supplements, bisphosphonates, raloxifine, hormone replacement therapies, teriparatide and calcitonin. However, all of these have their own shortcomings. Topical nitroglycerin is a cost-effective, novel medication that not only increases bone formation but also decreases its resorption, and also has the potential to decrease vertebral fractures more than that provided by the existing treatments. Therefore, it could be the answer to the need of an efficacious, cost-effective, affordable, safe and a convenient form of therapy for the prevention of post-menopausal bone loss and osteoporosis as a whole. Therefore, we recommend that individuals with osteoporosis be treated with topical nitroglycerine ointment (15 mg/day).

How to cite this article
Agrawal P, Agarwal A, Singh O, Bansal M. Topical Nitroglycerin: A New and Safe Treatment Option for Osteoporosis. J South Asian Feder Menopause Soc 2014;2(1):20-22.
Successful Pregnancy Outcome with Glioblastoma Multiforme of the Brain
Authors: Khandaker Shamim 
Published: November 2014

ABSTRACT
Brain tumors in pregnancy are uncommon occurrences. A 30-year-old female at 35 weeks of gestation presented with headache, left sided weakness and parasthesias. Brain imaging (MRI) studies revealed a left sided enhancing temporoparietal lesion with perilesional vasogenic edema and mass effect toward right side. She underwent an elective cesarean delivery. Glioblastoma multiforme is a rare diagnosis during pregnancy which may present as neurologic symptoms.

How to cite this article
Khandaker S. Successful Pregnancy Outcome with Glioblastoma Multiforme of the Brain. J South Asian Feder Menopause Soc 2014;2(1):31-32.
Role of Uterine Artery Embolization and Methotrexate in Cervical Pregnancy
Authors: LNU Pushpalatha , Lakshmi Vasantha , Radhakrishna Keerthi Patturu 
Published: November 2014

ABSTRACT
Cervical ectopic pregnancy in a 33-year-old gravida 8 para 1 live 1 abortion 6 following spontaneous conception at 6 weeks presented with mild vaginal spotting with no abdominal cramps. On pelvic exam, cervix slightly distended with no uterine enlargement and minimal bleeding at external orifice noted. Managed conservatively with three doses of methotrexate (MTX) and uterine artery embolization (UAE). The case is presented here for its rarity and to conclude successful conservative management is possible with MTX and UAE in treating early cervical pregnancy with mild vaginal bleeding with fetal heart allowing preservation of fertility.

How to cite this article
Radhakrishna KP, Lakshmi V, Pushpalatha. Role of Uterine Artery Embolization and Methotrexate in Cervical Pregnancy. J South Asian Feder Menopause Soc 2014;2(1):35-37.
A Case of Disseminated Peritoneal Tuberculosis Mimicking Metastatic Ovarian Carcinoma
Authors: Mishra Ishita , Pandya Nimish C , Surti Nilopher , Patel Babu S 
Published: November 2014

ABSTRACT

Background
Mycobacterium tuberculosis affects about 30% of world's population and infection occurs at a rate of one per second. In 2010, tuberculosis accounted for 8.8 million new cases, was responsible for 1.45 million deaths with majority of cases in developing countries. Tuberculosis is the most common cause of mortality in women of reproductive age. Peritoneal tuberculosis accounts for 4% of all extrapulmonary diseases and often mimics ovarian malignancy due to its nonspecific symptoms.

Case
A 25-year-old woman with ovarian mass and an elevated cancer antigen 125 (CA-125) underwent an exploratory laparotomy to search for ovarian tumor. The final pathological diagnosis was miliary abdominal tuberculosis.

Discussion
Peritoneal tuberculosis often mimics ovarian malignancy due to its nonspecific symptoms and is a major health problem in developing countries. There is no particular diagnostic test to differentiate this disease from advanced ovarian carcinoma, making it difficult to avoid extensive surgery. Laparoscopy is the diagnostic modality of choice.

How to cite this article
Surti N, Patel BS, Pandya NC, Mishra I. A Case of Disseminated Peritoneal Tuberculosis Mimicking Metastatic Ovarian Carcinoma. J South Asian Feder Menopause Soc 2014;2(1):44-45.
Successful Pregnancy Outcome by Repeat Cesarean Section and Herniorrhaphy in a Case of neglected ruptured Incisional Hernia
Authors: Nanda Smiti , Singhal Savita Rani , Sangwan Neetu , Singhal Suresh Kumar 
Published: November 2014

ABSTRACT

Objective
Gravid uterus with incisional hernia is rarely encountered complication. Aim is to report a case of pregnancy with ruptured incisional hernia.

Case report
A 35-year-old woman, gravida three, para two presented at 30 weeks of gestation with ruptured abdominal incisional hernia. She had previous two emergency cesarean sections done for contracted pelvis, 3 and 2 years back, respectively. Emergency herniorrhaphy was done. Postoperative period was uneventful and pregnancy advanced well without complication. At 37 weeks of gestation, she had elective cesarean section with bilateral tubal ligation. She delivered a healthy female baby of 2.5 kgs and the postoperative period was uneventful.

Conclusion
If the woman was aware and had come earlier during antenatal period; she would have been put on conservative management (bed rest, binder, etc) which might had prevented rupture of the hernia and further the emergency herniorrhaphy which is additional risk factor for the mother and the baby.

How to cite this article
Singhal SR, Sangwan N, Nanda S, Singhal SK. Successful Pregnancy Outcome by Repeat Cesarean Section and Herniorrhaphy in a Case of neglected ruptured Incisional Hernia. J South Asian Feder Menopause Soc 2014;2(1):50-51.
Incremental Validity of Emotional Intelligence Ability in Predicting Academic Achievement
Authors: Lanciano Tiziana , Curci Antonietta 
Published: November 2014

Abstract
We tested the incremental validity of an ability measure of emotional intelligence (EI) in predicting academic achievement in undergraduate students, controlling for cognitive abilities and personality traits. Academic achievement has been conceptualized in terms of the number of exams, grade point average, and study time taken to prepare for each exam. Additionally, gender differences were taken into account in these relationships. Participants filled in the Mayer–Salovey–Caruso Emotional Intelligence Test (MSCEIT), the Raven’s Advanced Progressive Matrices, the reduced version of the Eysenck Personality Questionnaire, and academic achievement measures. Results showed that EI abilities were positively related to academic achievement indices, such as the number of exams and grade point average; total EI ability and the Perceiving branch were negatively associated with the study time spent preparing for exams. Furthermore, EI ability adds a percentage of incremental variance with respect to cognitive ability and personality variables in explaining scholastic success. The magnitude of the associations between EI abilities and academic achievement measures was generally higher for men than for women. Jointly considered, the present findings support the incremental validity of the MSCEIT and provide positive indications of the importance of EI in students’ academic development. The helpfulness of EI training in the context of academic institutions is discussed.
Kidney and haemostasis
Authors: Andrassy K. 
Published: November 2014

SummaryRenal insufficiency is characterized by thrombocytopathy, caused by the accumulation of water soluble and protein bound waste products of protein metabolism, which are not adequately eliminated by the kidney. The kidneys also excrete drugs and their metabolites, which accumulate if dosages are not adjusted to the renal function and may cause clinically relevant bleeding (i. e. synthetic penicillins, vitamin K antagonists, new oral anticoagulants). Therefore, each patients kidney function (GFR) ought to be evaluated by the KDIGO guidelines. The survival of chronic renal patients is lowered by increasing cardiovascular complications. Particularly frequent is non-valvular atrial fibrillation. The recommended prophylaxis with vitamin K antagonists for renal insufficiency is hampered by increased bleeding as well as by augmented (coronary) vascular and valvular calcification. It is not known yet whether prophylaxis with vitamin K may prevent this complication. Conclusion: Because new oral anticoagulants are equally or even more effective and cause less bleeding, they may be favoured in future and even in end-stage renal failure if more is known about dosing, safety and efficacy. The measurement of serum FGF 23 concentration may be helpful as a marker for their use.
Concise Review: Modeling Central Nervous System Diseases Using Induced Pluripotent Stem Cells
Authors: Zeng Xianmin , Hunsberger Joshua G. , Simeonov Anton , Malik Nasir , Pei Ying , Rao Mahendra 
Published: November 2014

Abstract

Induced pluripotent stem cells (iPSCs) offer an opportunity to delve into the mechanisms underlying development while also affording the potential to take advantage of a number of naturally occurring mutations that contribute to either disease susceptibility or resistance. Just as with any new field, several models of screening are being explored, and innovators are working on the most efficient methods to overcome the inherent limitations of primary cell screens using iPSCs. In the present review, we provide a background regarding why iPSCs represent a paradigm shift for central nervous system (CNS) disease modeling. We describe the efforts in the field to develop more biologically relevant CNS disease models, which should provide screening assays useful for the pharmaceutical industry. We also provide some examples of successful uses for iPSC-based screens and suggest that additional development could revolutionize the field of drug discovery. The development and implementation of these advanced iPSC-based screens will create a more efficient disease-specific process underpinned by the biological mechanism in a patient- and disease-specific manner rather than by trial-and-error. Moreover, with careful and strategic planning, shared resources can be developed that will enable exponential advances in the field. This will undoubtedly lead to more sensitive and accurate screens for early diagnosis and allow the identification of patient-specific therapies, thus, paving the way to personalized medicine.
Osteogenic Differentiation of Human Amniotic Epithelial Cells and Its Application in Alveolar Defect Restoration
Authors: Jiawen Si , Jianjun Zhang , Jiewen Dai , Dedong Yu , Hongbo Yu , Jun Shi , Xudong Wang , Shen Steve G.F. , Lihe Guo 
Published: November 2014

Abstract

The present study investigated the detailed in vitro osteogenic differentiation process and in vivo bone regenerative property of human amniotic epithelial cells (hAECs). The in vitro osteogenic differentiation process of hAECs was evaluated by biochemical staining, real-time polymerase chain reaction, and immunofluorescence. Next, β-tricalcium phosphate (β-TCP) scaffolds alone or loaded with hAECs were implanted into the alveolar defects of rats. Micro-computed tomography evaluation and histologic studies were conducted. Our results validated the in vitro osteogenic capacity of hAECs by upregulation of Runx2, osterix, alkaline phosphatase, collagen I, and osteopontin, with positive biochemical staining for osteoblasts. An epithelial-mesenchymal transformation process might be involved in the osteogenic differentiation of hAECs by increased expression of transforming growth factor-β1. Our data also demonstrated that in vivo implantation of hAECs loaded on β-TCP scaffolds, not only improved bone regeneration by direct participation, but also reduced the early host immune response to the scaffolds. The presented data indicate that hAECs possess proper osteogenic differentiation potential and a modulatory influence on the early tissue remodeling process, making these cells a potential source of progenitor cells for clinical restoration of the alveolar defect.