bluuebunny/crossref_metadata_2025_split huggingface dataset:
Antimicrobial Resistance and New Antimicrobial Agents, A Review of the Literature
Authors: Huang Zhaoyu , Zhai Zhiyong , Zhou Ping , Li Wanjun , Hu Wei , Gong Wei 
Published: June 2024

Abstract:
Antibiotic resistance has progressively diminished the effectiveness of conventional
antibiotics, necessitating the cessation of clinical treatment. Consequently, novel
antibacterial agents are urgently needed. We review studies on antimicrobial agents
published during 2002-2023. Most of these studies were published within the last 10
years. By analyzing recent articles on antibiotic resistance and the development of new
antibacterial drugs, we showed that although drug resistance is inevitable, the issue is being
addressed gradually via the discovery and clinical application of antimicrobial peptides,
nanomaterial drugs, and bacteriophage therapy. In light of the emergence of antimicrobial
resistance, the development of new antimicrobial agents will require innovation
in a field that has relied on traditional methods of discovery and development.
Intramural Health Care Through Video Consultations and the Need for Referrals and Hospital Admissions: Retrospective Quantitative Subanalysis of an Evaluation Study
Authors: Schmalstieg-Bahr Katharina , Colombo Miriam Giovanna , Koch Roland , Szecsenyi Joachim , Völker Friedrich , Blozik Eva Elisabeth , Scherer Martin 
Published: June 2024

Background
In comparison to the general population, prison inmates are at a higher risk for drug abuse and psychiatric, as well as infectious, diseases. Although intramural health care has to be equivalent to extramural services, prison inmates have less access to primary and secondary care. Furthermore, not every prison is constantly staffed with a physician. Since transportation to the nearest extramural medical facility is often resource-intensive, video consultations may offer cost-effective health care for prison inmates.

Objective
This study aims to quantify the need for referrals to secondary care services and hospital admissions when video consultations with family physicians and psychiatrists are offered in prison.

Methods
In 5 German prisons, a mixed methods evaluation study was conducted to assess feasibility, acceptance, and reasons for conducting video consultations with family physicians and psychiatrists. This analysis uses quantitative data from these consultations (June 2018 to February 2019) in addition to data from a sixth prison added in January 2019 focusing on referral and admission rates, as well as reasons for encounters.

Results
At the initiation of the project, 2499 prisoners were detained in the 6 prisons. A total of 435 video consultations were conducted by 12 physicians (3 female and 7 male family physicians, and 2 male psychiatrists during the study period). The majority were scheduled consultations (341/435, 78%). In 68% (n=294) of all encounters, the patient was asked to consult a physician again if symptoms persisted or got worse. In 26% (n=115), a follow-up appointment with either the video consultant or prison physician was scheduled. A referral to other specialties, most often psychiatry, was necessary in 4% (n=17) of the cases. Only in 2% (n=8) of the consultations, a hospital admission was needed. Usually, hospital admissions were the result of unscheduled consultations, and the videoconferencing system was the method of communication in 88% (n=7) of these cases, while 12% (n=1) were carried out over the phone. Reasons for admissions were severe abdominal pain, hypotension, unstable angina or suspected myocardial infarction, or a suspected schizophrenic episode.

Conclusions
Most scheduled and unscheduled consultations did not require subsequent patient transport to external health care providers. Using telemedicine services allowed a prompt patient-physician encounter with the possibility to refer patients to other specialties or to admit them to a hospital if necessary.
КОЭФФИЦИЕНТ ПРОДОЛЬНОГО ИЗГИБА СТАЛЕЖЕЛЕЗОБЕТОННЫХ СТОЕК ПРИ КРАТКОВРЕМЕННОМ ДЕЙСТВИИ НАГРУЗОК
Authors: Конин Денис 
Published: June 2024

Рассмотрены нормы по расчету сжатых сталежелезобетонных стоек, а также экспериментально-теоретические исследования других авторов. Выполнено экспериментальное исследование работы сжатых стоек с малым эксцентриситетом на диапазоне гибкостей от 6 до 20. Выполнено численное моделирование различных вариантов конструкций: с бетонами от В30 (С25/30) до В100 (С90/105), с сердечником в виде двутавра, с сердечником в виде квадрата. Полученные данные экспериментов и расчетов сопоставлены с теоретическими кривыми коэффициента продольного изгиба. Установлено, что кривые коэффициента в СП 266.1325800 и Eurocode 4 имеют не корректную форму и не отражают действительной работы сталежелезобетонных сжатых элементов. Использование кривой СП 266.1325800, основанной на кривой для железобетонных конструкций, а также кривых Eurocode 4, которые приняты как для стальных сечений (по Eurocode 3) – не дает нормального запаса конструкций и не обеспечивает надежность. Оба норматива игнорируют различный характер работы бетонов обычной и высокой прочности. В результате исследований установлено, что класс прочности бетона на сжатие влияет на устойчивость стержней с гибкостью от 6 до 10, при этом влияния формы поперечного сечения сердечника (вида жесткого армирования) практически нет. Для гибкостей от 10 до 20 может быть принята единая для всех бетонов кривая коэффициента. Разработаны кривые коэффициента для расчета сжатых элементов при малых эксцентриситетах и кратковременном действии нагрузок; предложена формула расчета несущей способности сжатых стоек.
Municipal waste management as a local government task – legal and organizational challenges
Authors: Milewska Anna , Bogucka Karolina 
Published: June 2024

The article presents the organisational and legal conditions behind a municipal waste management system. The authors reviewed the subject literature on the functioning of local government and public services theory, focusing on municipal waste management. The paper also contains acts governing international and national law. They define, in the light of the central hierarchy of waste, the types and magnitude of necessary measures to be implemented in this area. They cover both requirements of quantity and quality.
Analysis of E-SPT and E-filing utilization on taxpayer compliance: A multiple regression approach
Authors: Rinaldi Achi , Devi Yulistia , Saleh Dana Taha Mohammed 
Published: June 2024

Background: Statistical data from Lampung Province indicate a steady annual increase in the number of taxpayers utilizing e-SPT (electronic tax return) and e-filing, particularly from 2019 to 2022.Aim: This study aims to analyze the effect of e-SPT usage on taxpayer compliance, investigate the impact of e-filing on taxpayer compliance, assess the combined effects of e-SPT and e-filing on taxpayer compliance, and understand taxpayer compliance within the framework of Islamic Economics.Method: Taxpayers from the Bandar Lampung Tax Office (KPP) were selected as respondents. A random sampling technique was employed to gather data from 100 participants. The data were analyzed using multiple linear regression analysis with SPSS.Results: The findings reveal that the convenience, effectiveness, and satisfaction derived from using e-SPT and e-filing, along with an analysis of Annual Tax Returns, significantly influence taxpayer compliance. The use of e-SPT alone has a notable impact on compliance, as does the use of e-filing. Furthermore, the combined usage of e-SPT and e-filing has a significant collective impact on taxpayer compliance.Conclusion: The study concludes that both e-SPT and e-filing are critical in enhancing taxpayer compliance, with their combined application having a more substantial effect. These findings also offer insights into taxpayer compliance from the perspective of Islamic Economics, emphasizing the role of modern tax administration tools in promoting compliance.
Heaven on Earth: Theory and Practice. Review of <i>The Christian Left</i>
Authors: Gorshenyov D. S. 
Published: June 2024

It is a well-know fact that the political legacy of Christianity is diverse and contradictory. But if we put forward the thesis that the legacy is also cyclical, we will open a large room for discussion both from the historical and political-theoretical perspective. Indeed, the first followers of Christianity were among the oppressed financially and socially, howewher with the advent of the institution of the church their status changed. Gradually the Christian church transformed into political force. We can evaluate it as a conservative right-wing political force. Over the past 150 years, as Anthony A. J. Williams, a British researcher of political theory at Manchester Metropolitan University, suggests and proves in his book The Christian Left, this thesis is far from the truth, and the provisions of the Bible can be the basis of economic collectivism and social liberation in the socialists’ understanding. Starting his research with the theological foundations of Christianity, which could be adopted not only by the right but also by the left, the author immerses the reader in the hitherto unexplored world of Christian socialism with all its contradictions and distrust on the part of the church. In his research, Williams tries to trace the genesis of this phenomenon in space and time, capturing the events of the 15th-16th centuries, when peasant uprisings on the one hand and religious reformers on the other opposed the established socio-economic order, proclaiming the earth a common treasury, advocating for universal brotherhood instead of competition, and fair distribution of income instead of thoughtless accumulation. Speaking broadly about the book we should admit that the author managed to collect, systematize and analyze both the intellectual and historical heritage of the Christian left movements. A. Williams managed to bring together both the prehistory, the philosophical, and the religious basis of left-wing Christianity. At the same time, the author does not reconsider the Christian dogmas, taking ready-made interpretations of socialist theologians without proper commentary and analysis. Furthermore the author does not develop the theory of left-wing Orthodox tradition. Nevertheless the book The Christian Left may be of interest to researchers of political theory, philosophers, theologians, sociologists and historians, as well as to anyone who doubts whether socialism is a successful attempt to build a paradise on earth.
Wizyta Margaret Thatcher w Polsce (2-4 listopada 1988 r.) w świetle dokumentów brytyjskiego Foreign Office
Authors: Drozdowski Mateusz 
Published: June 2024

Celem artykułu pozostaje analiza okoliczności, przygotowań, przebiegu oraz oceny wizyty premier Wielkiej Brytanii, Margaret Thatcher, w Polsce w dniach 2-4 listopada 1988 r. Omawiane wydarzenie było pierwszą wizytą przywódcy zachodniego mocarstwa po wprowadzeniu stanu wojennego w 1981 r. i w ogóle pierwszym w historii pobytem premiera Zjednoczonego Królestwa nad Wisłą, stanowiło też ważny moment w procesie przezwyciężania izolacji politycznej, w jakiej znalazły się komunistyczne władze Polski po kryzysie solidarnościowym lat 1980-1981. Co więcej, wizyta ta miała miejsce w krytycznym momencie historii Polski - na trzy miesiące przed rozpoczęciem rozmów Okrągłego Stołu (luty-kwiecień 1989), kiedy losy tego projektu wydawały się bardzo niepewne. Biorąc pod uwagę okoliczności, celem Margaret Thatcher pozostawało nie tylko rozwijanie dwustronnych stosunków między obydwoma państwami, ale też wsparcie Solidarności, wywarcie nacisku na władze PRL odnośnie rozpoczęcia negocjacji z opozycją oraz wprowadzenie polityczno-gospodarczych reform. Artykuł opiera się na literaturze tematu oraz przede wszystkim na źródłach dostępnych w brytyjskim Archiwum Narodowym (Londyn, Kew).
„Gut versteckt ist besser wie gedeckt”. Radomszczańscy Żydzi w obliczu likwidacji getta
Authors: Gliksman Adam 
Published: June 2024

Getto w Radomsku zostało utworzone już w grudniu 1939 r. Szacuje się, że przez blisko trzy lata jego istnienia przebywało w nim ponad 20 tysięcy Żydów. W październiku 1942 r. w ramach akcji „Reinhardt” rozpoczęto deportację mieszkańców dzielnicy żydowskiej, która doprowadziła do ich zgładzenia. Celem artykułu jest zrekonstruowanie sytuacji w getcie w Radomsku w przededniu rozpoczęcia wysiedleń w 1942 r. oraz próba odpowiedzi na pytanie o stopień świadomości zbliżającego się zagrożenia. W oparciu o relacje ocalałych podjęto próbę ustalenia, jaką wiedzą na temat przebiegu i rzeczywistego celu akcji deportacyjnej dysponowali radomszczańscy Żydzi, jak reagowali na docierające wiadomości i jakie działania w oparciu o nie podejmowali.
Service Cultures, Personalities, and the Struggle to Establish a Joint Headquarters in Halifax during the Second World War
Authors: Goette Richard 
Published: June 2024

The Royal Canadian Air Force (RCAF) and Royal Canadian Navy (RCN) sought to emulate their British counterparts in joint defence of convoys. However, a strange omission was the inability of Canadian aviators and sailors to come together in a joint headquarters in Halifax until July 1943 – fully five years after the British and one year after the United States. Why was this so? Many factors account for this failure. They include resource constraints, physical location issues, and communications systems considerations. However, the most important factors were service culture and individual personalities, notably conceptions regarding air-naval jointness and command and control.
L’Aviation royale canadienne et la Marine royale canadienne cherchaient à imiter leurs homologues britanniques dans la défense conjointe des convois. Cependant, l’incapacité des aviateurs et des marins canadiens à se réunir dans un quartier général interarmées à Halifax avant juillet 1943, cinq ans après la Grande-Bretagne et un an après les États-Unis, semblait des plus étranges. Pourquoi en était-il ainsi? De nombreux facteurs expliquent cet échec, notamment les contraintes au niveau des ressources, les questions d’emplacement physique et les considérations relatives aux systèmes de communication. Pourtant, les facteurs les plus importants étaient la culture de service et les personnalités individuelles, notamment les conceptions de l’interarmisation de l’armée et de la marine, le commandement et le contrôle.
Pandemia da covid-19 e suas repercussões para a saúde psicossocial dos adolescentes
Authors: Silva Érika Mendes da , Lourenço Elâyne Sousa , Silva Ana Carolina de Oliveira e , Silveira Maria Adelaide Moura da , Marques Juliana Freitas 
Published: June 2024

Objetivo: Conhecer as repercussões da pandemia da ovid-19 sobre a saúde psicossocial dos adolescentes. Método: Revisão integrativa realizada nas bases de dados SCIELO, LILACS e PUBMED, utilizando os descritores: saúde do adolescente; saúde mental; covid-19. Foram selecionados artigos originais, publicados na íntegra, nos idiomas português, inglês e espanhol. Resultados: Foram extraídos 11 artigos, cujas temáticas foram categorizadas em: emoções e comportamentos negativos desenvolvidas nos adolescentes durante pandemia da covid-19; consequências psicossociais da pandemia sobre o processo de adolescer; intervenções realizadas com adolescentes para a promoção da saúde mental. Dentre as emoções negativas, destacam-se a solidão, medo e angústia. Os principais transtornos elencados foram a ansiedade, depressão, ideações suicidas e suicídio. Considerações finais: Foi possível constatar que a pandemia da covid-19 trouxe alterações emocionais e comportamentais entre os adolescentes, repercutindo negativamente sobre sua saúde mental. Ressalta-se a importância da realização de ações de promoção da saúde psicossocial voltada aos adolescentes.
VG111: A novel formulation demonstrating clinical evidence of anti-pathogenic activity and accelerated wound healing in humans and companion animals
Authors: Singhal Lipika , Singh Kanwar A. , Panda Rajendra K. , Malik Yashpal S. , Verma Rahul Kumar , Ghosh Deepa , Singh Navdeep , Kaur Paviter , Batra Priyam , Khare Siddhant , Batra Vipul , Kumar Rajesh , Chakraborty Surajit , Shekhar Nishant , Bhattacharyya Shalmoli , Vasisht Karan , Sharma Ashish , Gautam Vikas 
Published: June 2024

Objectives:
The increasing incidence of chronic wounds such as diabetic foot ulcers and pressure ulcers, often compounded by bacterial infections and biofilm formation, presents significant challenges in wound management. Despite advancements in wound care products and a better understanding of molecular wound repair mechanisms, the treatment of chronic ulcerating conditions remains incomplete. VG111, a novel natural product formulation, emerges as a promising therapeutic candidate addressing the need for an effective wound healing agent with antimicrobial and tissue regenerative properties.

Materials and Methods:
A thorough evaluation of VG111 included antimicrobial assays to determine its minimum inhibitory concentration against an array of pathogens, assessment of its biofilm disruption capabilities, investigation into its profibrogenic activity through scratch assays, and analysis of its immunomodulatory effects on macrophage-derived cytokines. Quality consistency was ensured by high-performance liquid chromatography fingerprinting, while clinical applicability was assessed through observations in canine and human wound healing cases.

Statistical Analysis:
The cytotoxic effects of VG111 were assessed using a Two-way ANOVA, indicating no significant cytotoxicity at the tested concentration (Column factor p<0.0001).

Results:
VG111 demonstrated potent antimicrobial action with effective concentrations ranging from 2.5% to 5.0% v/v, targeting resistant strains of Methicillin-resistant Staphylococcus aureus, colistin-resistant Escherichia coli, Acinetobacter baumannii, and other priority pathogens. It showed biofilm clearance, enhanced fibroblast migration, and a favorable immunomodulatory profile by reducing inflammatory cytokines in vitro. In vivo applications corroborated these findings, with significant wound healing observed in both veterinary and clinical settings, negating the need for additional antibiotics.

Conclusions:
The study emphasized on VG111 as a robust wound healing agent with significant antimicrobial and biofilm-disrupting properties. Its broad-spectrum efficacy against critical pathogens and ability to promote tissue regeneration mark it as a promising avenue in the management of complex chronic wounds, meriting further clinical exploration.
ẢNH HƯỞNG CỦA MỘT SỐ YẾU TỐ ĐẾN KHẢ NĂNG SINH TRƯỞNG VÀ PHÁT TRIỂN CÂY CHÈ VẰNG (Jasminum subtriplinerve) TRONG GIAI ĐOẠN VƯỜN ƯƠM
Authors: Tân Nguyễn Duy Ngọc , Đức Trần Minh , Thành Phạm , Hoàn Nguyễn Văn , Lam Nguyễn Hồ 
Published: June 2024

Nghiên cứu này được thực hiện nhằm đánh giá ảnh hưởng của các yếu tố đến sinh trưởng và phát triển của cây chè Vằng (Jasminum subtriplinerve) trong giai đoạn vườn ươm. Các thí nghiệm được bố trí theo phương pháp Split – Splot, ba lần lặp lại. Trong đó, thí nghiệm 1, ô lớn là 6 nồng độ chất điều hòa sinh trưởng (ĐHST) 3-Indoleacetic acid (IAA) và ô nhỏ là 3 loại hom; thí nghiệm 2, ô lớn là 3 loại thành phần giá thể và ô nhỏ là 4 diện tích cắt lá. Sau 90 ngày, các chỉ tiêu sinh trưởng của các công thức tốt nhất của thí nghiệm 1 và 2 lần lượt là: tỷ lệ sống: 83,33, 83,00%; tỷ lệ nảy chồi: 96,67, 96,67%; số chồi: 3,00, 3,40 chồi/hom; chiều cao: 12,93, 12,77 cm; đường kính: 0,86, 0,93 mm; số lá/chồi: 5,80, 5,93 và chỉ số ra rễ: 122,62, 199,04 cm. Kết quả nghiên cứu này chỉ ra rằng, công thức nhân giống loài chè Vằng có thể áp dụng trong giai đoạn vườn ươm là: loại hom bánh tẻ, độ dài 15 – 20 cm, có ít nhất 3 – 4 mắt dương; số lá để lại 2 – 4 lá, cắt bỏ 1/3 diện tích lá; chất ĐHST là IAA, nồng độ 1.000ppm; giá thể gồm 60% đất phù sa cổ + 10% cát + 22% phân chuồng + 5% phân vi sinh + 3% NPK.
ẢNH HƯỞNG CỦA CHẾ PHẨM SINH HỌC CHỨA VI KHUẨN Pediococcus pentosaceus LÊN SINH TRƯỞNG, HIỆU QUẢ SỬ DỤNG THỨC ĂN VÀ ENZYME TIÊU HÓA CỦA CÁ DÌA (Siganus guttatus, Bloch 1787)
Authors: Chất Tôn Thất , Nghĩa Lê Văn , Mạnh Hoàng Nghĩa 
Published: June 2024

Nghiên cứu này nhằm đánh giá ảnh hưởng của việc bổ sung vi khuẩn Pediococcus pentacocceus vào thức ăn lên sinh trưởng, hiệu quả sử dụng thức ăn và hoạt tính enzyme tiêu hóa của cá dìa (Siganus guttatus, Bloch 1787). Cá giống (4,63 ± 0,41 g) được cho ăn 3 khẩu phần ăn có bổ sung vi khuẩn ở các mật độ khác nhau, bao gồm P. pentosacceus ở 107 CFU/g (T1), 108 CFU/g (T2), 109 CFU/g (T3) và một khẩu phần đối chứng (CT) không bổ sung P. pentosacceus. Mỗi khẩu phần được lặp lại 3 lần. Sau 60 ngày nuôi, kết quả cho thấy bổ sung P. pentosacceus cải thiện tốc độ sinh trưởng, hiệu quả sử dụng thức ăn và hoạt tính enzyme tiêu hóa của cá. Các chỉ tiêu sinh trưởng như khối lượng cuối (20,06 g), mức tăng khối lượng (331,96%) và tốc độ sinh trưởng (0,25 g/con/ngày) cao nhất được tìm thấy ở T2 và có sự khác biệt so với các nghiệm thức còn lại (p < 0,05). Tương tự, hoạt tính enzyme tiêu hóa gồm amylase, lipase và protease có sự tăng lên ở nhóm cá được cho ăn thức ăn có bổ sung chế phẩm so với nhóm đối chứng. Kết quả nghiên cứu này khuyến khích bổ sung vi khuẩn P. pentosacceus (mật độ 108 CFU/g) vào thức ăn để nâng cao sinh trưởng, hiệu quả sử dụng thức ăn và hoạt tính enzyme tiêu hóa của cá dìa.
ECONOMETRIC ANALYSIS OF DETERMINANTS INFLUENCING RISK-ADJUSTED PERFORMANCE OF MUTUAL FUNDS
Authors: Benomar Ikram , Haj Fouad Ben El 
Published: June 2024

Objective: This study explores the relationship between Mutual Funds' (UCITS) performance and nine macroeconomic variables using a Vector Autoregressive (VAR) model. It aims to understand the dynamics between these variables and UCITS performance.

Theoretical Framework: The study is grounded in economic theories and concepts relevant to macroeconomics and financial markets. The VAR model serves as the theoretical framework, facilitating the analysis of the interdependencies among variables.

Method: The research methodology involved the application of a VAR model to 92 quarterly observations from January 2000 to December 2022. Non-stationarity tests indicated that all variables were non-stationary in levels but became stationary after first-order differencing. Data collection methods included obtaining information on macroeconomic variables and OPCVM performance.

Results and Discussion: The findings indicate a long-term causality between OPCVM performance, and the macroeconomic variables studied. Significant variables affecting OPCVM performance include money supply, GDP, inflation rate, discount rate, and bond interest rate. However, interest rate and exchange rate showed no significant impact. The presence of an inertia effect suggests the utilization of Box-Jenkins ARMA modeling.

Research Implications: This study provides insights into the influence of macroeconomic factors on OPCVM performance, offering implications for investors, financial analysts, and policymakers. Understanding these relationships can aid in making informed investment decisions and formulating effective economic policies.

Originality/Value: The research contributes to the literature by employing a VAR model to analyze the relationship between OPCVM performance and macroeconomic variables in the context of the Moroccan market. The findings offer practical implications for stakeholders and advance the understanding of financial market dynamics.