bluuebunny/crossref_metadata_2025_split huggingface dataset:
Scatterhoarder abundance and advantages of seed burial drive dynamics of a tree–rodent interaction
Authors: Zwolak Rafał , Celebias Paulina , Zduniak Milena , Bogdziewicz Michał , Wróbel Aleksandra 
Published: June 2024

Abstract

Theoretical models suggest that species abundance plays a crucial role in mutualism; high densities can lead to overexploitation. Additionally, mutualistic benefits are expected to increase under abiotic stress.

We investigated the interplay between density dependence and abiotic factors in conditional mutualism, focussing on the interactions between yellow‐necked mice (Apodemus flavicollis) and common oaks (Quercus robur) across 3 years. We controlled for seed abundance, while mouse densities varied. Our approach included monitoring mouse abundance, measuring seed removal, determining the fate of harvested seeds and conducting seedling emergence trials to assess the advantages of seeds caching.

We found that mouse abundance exerted a strong influence on all studied aspects of seed dispersal. Higher densities led to increased seed removal and greater dispersal distances. However, they also decreased the probability of seed caching and increased seed consumption, degrading dispersal quality and shifting the interaction towards antagonism. Furthermore, the reliance of seedling recruitment on burial varied over time, likely becoming more critical during dry conditions. This indicates that plants face the worst conditions when high abundance of mice coincides with abiotic stress.

Synthesis: Our results supports the notion that increased rodent abundance reduces plant recruitment, revealing the conflicting interests of the interacting species. However, the dynamics of rodent–oak interactions are shaped not only by the density‐dependent foraging decisions of rodents, but also by the benefits of seed burial under stress. These findings illustrate how the interplay between population density and abiotic factors jointly dictate the costs and benefits of mutualistic interactions.
Metal hyperaccumulation in the Indonesian flora
Authors: Brearley Francis Q. 
Published: June 2024

AbstractIn this review, I examined the number, distribution, and metal concentrations of all known metal hyperaccumulator plants from Indonesia. In total, 72 hyperaccumulator taxa were found: 19 accumulated Ni, 42 accumulated Al, 7 accumulated Cu, 2 accumulated Zn, and 2 accumulated Co in addition to Ni. There were six hypernickelophores with greater than 1% foliar nickel and with potential for agromining. Less than 10% of the hyperaccumulator species were single island endemics, and only one had an endangered status. Given that many species were only recorded from locations with mining activity, conservation assessments and actions should urgently be undertaken. There are undoubtedly many more hyperaccumulators to be found across Indonesia that will be discovered with further inter‐disciplinary surveys.
Preparedness and emergency response strategies for chemical, biological, radiological and nuclear emergencies in disaster management: A qualitative systematic review
Authors: Farhat Hassan , Alinier Guillaume , Chaabna Karima , El Aifa Kawther , Abougalala Walid , Laughton James , Ben Dhiab Mohamed 
Published: June 2024

AbstractDisaster management, mainly related to chemical, biological, radiological and nuclear (CBRN) incidents, is a critical field that requires constant evaluation to improve preparedness and response strategies. This review synthesises evidence on global health sector strategies for CBRN preparedness, gathering lessons to enhance policymaking for future response and readiness. This review included original English and French research addressing healthcare preparedness for CBRN threats. Database searches, such as EBSCO, ScienceDirect, PubMed, Ovid, Lissa, and Santécom, were conducted until November 2022. The Joanna Briggs Institute's tools were utilised to assess the risk of bias. Al‐Raayan® and Nvivo® version 12 software were employed for the review and analysis. 57 articles in English and 6 in French met the inclusion criteria. The analysis identified numerous strategies, concentrating on chemical and biological incidents (Chemical and biological bioterrorism: n = 27; Epidemics and Outbreak: n = 15). “Hospitals”, “responsibility”, and “health” emerged as prominent keywords, emphasising institutional roles and health outcomes in CBRN incidents preparedness. Key findings highlighted the need for a unified global definition of bioterrorism to align international efforts. Hospital‐level initiatives were emphasised as the foundation for national preparedness, emphasising specialised training, community engagement, and robust coordination mechanisms. Geographical variability in response strategies was noted, necessitating a harmonised global approach. Continuous research, epidemic management, and addressing radiological/nuclear threats emerged as crucial elements. Among others, strategies defined under “Emergency Response Preparedness” and “Intersectoral Policy Development” outlined comprehensive preparedness contexts for CBRN incidents. The review suggests an imperative shift towards building collaborative networks and enhancing health sector operational readiness to mitigate the impacts of CBRN incidents.
Comparing the psychological outcomes of donor and non‐donor conceived people: A systematic review
Authors: Talbot Charlotte , Hodson Nathan , Rose Joanne , Bewley Susan 
Published: June 2024

AbstractBackgroundOver 70 000 donor‐conceived (DC) people have been born in the UK since 1991. Little is known about their long‐term psychological outcomes and no systematic review has assessed these.ObjectivesTo conduct a systematic review of the psychological experiences of DC people through childhood and adulthood (Prospero: CRD42021257863).Search strategySearches of Cumulative Index to Nursing and Allied Health Literature (CINHAL), the Excerpta Medica database (Embase), MEDLINE® and PsycINFO, conducted on 4 January 2024.Selection criteriaQuantitative and qualitative studies were included if: there were five or more participants; they were peer reviewed; and any DC psychological outcomes were assessed. No limits on date, language or country were applied.Data collection and analysisDouble screening, selection, data extraction and quality assessment were performed, using Joanna Briggs Institute (JBI) scoring.Main resultsFifty studies (with 4666 DC participants), mostly from high‐income anglophone countries, with heterogeneity of design, populations and outcome measures, were included. Of 19 comparative studies, 14 found no difference in outcomes between DC and non‐DC people, ten found better outcomes (in health, well‐being, self‐esteem and emotional warmth) and six found worse outcomes (increased autism spectrum disorder and attention deficit hyperactivity disorder, addiction issues, mental illness, disruptive behaviour and identity problems). Qualitative data revealed common themes relating to identity formation, mistrust and concerns regarding genetic heritage. The evidence regarding adulthood outcomes was very limited.ConclusionsThe research on DC individuals presents a nuanced picture, with most studies suggesting comparable or improved outcomes in terms of well‐being and relationships, but with a notable minority indicating higher rates of mental health and identity struggles. Qualitative findings underscore common negative experiences, whereas the early disclosure of DC status appears beneficial for psychological well‐being.
Managing falls onsite in residential aged care homes reduced hospitalisation: Mixed methods results from the Falls Outreach and Residential Mobile Assessment Team (FORMAT) pilot study
Authors: Miller Joseph , Bee Andrea , Pattison Donna , Walker Megan , Aldridge Emogene , Hackett Liam , Owen Patrick J. , Marangon‐Elliott Renee , Buntine Paul 
Published: June 2024

AbstractObjectiveFalls are the leading cause of hospital transfer from residential aged care homes (RACHs). However, many falls do not result in significant injury, and ageing patients are exposed to complications while hospitalised. Inreach services are designed to reduce hospital transfer by providing care, support and assessment to residents at the RACH. This study evaluated a pilot inreach program targeting ageing patients following a fall.MethodsWe conducted a prospective, mixed methods evaluation of a 5‐month (May–September 2022) pilot implementation across 108 government‐funded RACHs within a single health‐care network in Melbourne, Australia.ResultsA total of 123 residents (median [interquartile range] age: 88 [82, 94] years, female: 49%) were included in the intervention. The majority (n = 116, 94%) of residents were managed onsite and required no further investigation (n = 80, 69%) or treatment (n = 63, 54%). Among the seven residents referred to the emergency department (ED), two received hospital admission and five were transferred back to residential care. In the 7 days following referral to the intervention, four additional residents were referred to the ED and one received hospital admission. Qualitative feedback (n = 40) included specific comments relating to themes of general satisfaction (n = 20, 50%), compliments for staff (n = 16, 40%) and acknowledgement of comprehensiveness (n = 9, 23%).ConclusionsImplementation of a specialised fall assessment team to complement an existing geriatric‐led RACH assessment service meant that a high rate of eligible residents were managed onsite, with very low need for subsequent hospitalisation. Residents, family members and caregivers expressed high rates of satisfaction with the service.
Configurational paths of entrepreneurial activity: An analysis based on the technology–organization–environment framework
Authors: Gong Xiuyuan , Li Lu , Yao Nengzhi , Guo Qiaozhe 
Published: June 2024

AbstractEntrepreneurial activity is crucial for economic progress and resolving societal issues. Utilizing the technology–organization–environment (TOE) theoretical framework, this study builds a systematic model to investigate the trajectories of entrepreneurial activities across 31 provinces in China from 2019 to 2021. We employ the fuzzy set qualitative comparative analysis (fsQCA) method. Our analyses indicate that (1) multiple factors impact both high entrepreneurial activity and non‐high entrepreneurial activity; entrepreneurial activity is significantly different between advanced and catching‐up regions; (2) there are two types of paths that lead to high entrepreneurial activity, namely technology driven and technology–institution driven. These paths are dynamic, gradually transitioning from technology driven and technology–institution driven to industry–resource driven; and (3) non‐high entrepreneurial activity may result from poor technological infrastructure and lack of human capital. These findings elucidate the different routes through which entrepreneurial activity is generated in China and offer valuable theoretical and practical insights.
The efficacy of online physical activity interventions with added mobile elements within adults aged 50 years and over: Randomized controlled trial
Authors: Collombon Eline H. G. M. , Bolman Catherine A. W. , de Bruijn Gert‐Jan , Peels Denise A. , Verboon Peter , Lechner Lilian 
Published: June 2024

AbstractElectronic health (eHealth) and mobile health (mHealth) could stimulate physical activity (PA) in a time‐efficient and cost‐effective way. This randomized controlled trial aims to investigate effects on moderate‐to‐vigorous PA (MVPA) of different combined computer‐ and mobile‐based PA interventions targeted at adults aged 50 years and over. Participants (N = 954) were randomly allocated to a basic existing computer‐based intervention (Active Plus [AP] or I Move [IM]) supplemented with one of three mobile elements being (1) activity tracker (AT), (2) ecological momentary intervention (EMI), or (3) chatbot (CB) or a control group (CG). MVPA was assessed via the SQUASH at baseline (T0), 3 months (T1), and 6 months (T2) and via accelerometers at T0 and T2. No intervention effects were found on objective (p = .502) and subjective (p = .368) MVPA for main research groups (AP/IM + AT, AP/IM + EMI, AP/IM + CB). Preliminary MVPA findings for subgroups (AP + AT, AP + EMI, AP + CB, IM + AT, IM + EMI, IM + CB) combined with drop‐out data showed potential for the computer‐based intervention AP with an integrated AT. Based on these preliminary findings, eHealth developers can be recommended to integrate ATs with existing computer‐based PA interventions. However, further research is recommended to confirm the findings as a result of the exploratory nature of the subgroup analyses.
Shape variation in the snapping claw of Alpheus Fabricius, 1898 (Decapoda: Alpheidae): A geometric morphometrics approach
Authors: Nascimento Whandenson M. , Almeida Alexandre O. , Pinheiro Allysson P. 
Published: June 2024

AbstractThe evolutionary success of the Alpheus snapping shrimps is linked to their snapping claws, which were considered the key innovation in the evolution of these shrimps. However, many aspects of the evolution of snapping claws remain unknown. We evaluate the degree of intra‐ and interspecific variation in the shape of the snapping claw in different snapping shrimp Alpheus species. For this, we used a geometric morphometric tool. We investigated the variation in snapping claw shape from two perspectives — interspecific variation and sexual shape dimorphism — in three species: Alpheus angulosus, A. carlae, and A. estuariensis, from three locations along the southern coast of Bahia state in northeastern Brazil. Our results revealed interspecific variation in the shape of the snapping claw among A. angulosus, A. carlae, and A. estuariensis. In addition, sexual shape dimorphism was confirmed in A. angulosus and A. carlae. However, in A. estuariensis, our results reveal sexual monomorphism in the snapping claw. Our findings highlight the importance of considering both ecological context and phylogenetic relationships when analysing the morphology of the snapping claw in Alpheus snapping shrimps. We suggest further investigations to better understand the interspecific variation and sexual dimorphism in snapping claws and their implications for the evolutionary history of these shrimps.
Intrusive thoughts and memories in adolescents with major depressive disorder or post‐traumatic stress disorder
Authors: Kralj Aleksandra , Payne Alexandra , Holzhauer‐Conti Olivia , Young Judith , Meiser‐Stedman Richard 
Published: June 2024

AbstractObjectivesResearch in adults suggests that intrusive memories and intrusive thoughts (often referred to as intrusive cognitions) are common in members of the general population and are often seen in clinical disorders. However, little is known about the experience of intrusive cognitions in adolescents, particularly in adolescents with major depressive disorder (MDD) and post‐traumatic stress disorder (PTSD). The present study sought to gather fundamental data on these phenomena (i.e., frequency, characteristics and appraisals of intrusive cognitions) in adolescents with MDD and PTSD.MethodsAdolescents aged 11–18 with MDD (n = 11), PTSD (n = 13) and a non‐clinical control group (n = 25) completed structured interviews concerning their intrusive memories and thoughts.ResultsIntrusive thoughts were common in all three groups but were particularly frequently experienced in the MDD group. Intrusive memories were expectedly very common in the PTSD group but also experienced by over half of the adolescents with MDD. Both clinical groups reported more negative emotions in response to their intrusive thoughts or memories and appraised these cognitions more negatively than the non‐clinical group.ConclusionIntrusive memories and thoughts are common experiences in adolescents with MDD and PTSD. Emotions and appraisals relating to these cognitions may be targets for psychological intervention in this age group. However, small sample sizes limit the conclusions that can be drawn. Replication is needed with larger numbers of clinical participants.
Relevance of repeated analyses of albuminuria and glomerular filtration rate in African children with sickle cell anaemia
Authors: Nkoy Agathe B. , Mumaka Floreen M. , Ngonde Ange , Mafumba Samuel K. , Matoka Therance T. , Kitenge Robert , Talu Flore M. , Nkolomoni Blaise , Tshilolo Léon , van den Heuvel Lambertus P. , Ekulu Pépé M. , Levtchenko Elena N. , Labarque Veerle 
Published: June 2024

SummaryGlomerular hyperfiltration and albuminuria are frequent kidney abnormalities in children with sickle cell anaemia (SCA). However, little is known about their persistence in African SCA children. This prospective study included 600 steady‐state SCA children aged 2–18 years from the Democratic Republic of Congo. Participants were genotyped for apolipoprotein L1 (APOL1) risk variants (RVs) and haem oxygenase‐1 (HMOX1) GT‐dinucleotide repeats. Kidney abnormalities were defined as albuminuria, hyperfiltration or decreased estimated creatinine‐based glomerular filtration rate (eGFRcr). At baseline, 247/600 (41.2%) participants presented with kidney abnormalities: 82/592 (13.8%) with albuminuria, 184/587 (31.3%) with hyperfiltration and 15/587 (2.6%) with decreased eGFRcr. After a median follow‐up of 5 months, repeated testing was performed in 180/247 (72.9%) available participants. Persistent hyperfiltration and persistent albuminuria (PA) were present in 29.2% (38/130) and 39.7% (23/58) respectively. eGFR normalized in all participants with a baseline decreased eGFRcr. Haemoglobinuria (p = 0.017) and male gender (p = 0.047) were significantly associated with PA and persistent hyperfiltration respectively. APOL1 RVs (G1G1/G2G2/G1G2) were borderline associated with PA (p = 0.075), while HMOX1 long repeat was not associated with any persistent kidney abnormality. This study reveals that a single screening can overestimate the rate of kidney abnormalities in children with SCA and could lead to overtreatment.
Histone deacetylase inhibition mitigates cognitive deficits and astrocyte dysfunction induced by amyloid‐β (Aβ) oligomers
Authors: Diniz Luan Pereira , Morgado Juliana , Bergamo Araujo Ana Paula , da Silva Antônio Leticia Maria , Mota‐Araujo Hannah Paola , de Sena Murteira Pinheiro Pedro , Sagrillo Fernanda Savacini , Cesar Gabriele Vargas , Ferreira Sérgio T. , Figueiredo Cláudia Pinto , Manssour Fraga Carlos Alberto , Gomes Flávia Carvalho Alcantara 
Published: June 2024

Background and PurposeInhibitors of histone deacetylases (iHDACs) are promising drugs for neurodegenerative diseases. We have evaluated the therapeutic potential of the new iHDAC LASSBio‐1911 in Aβ oligomer (AβO) toxicity models and astrocytes, key players in neuroinflammation and Alzheimer's disease (AD).Experimental ApproachAstrocyte phenotype and synapse density were evaluated by flow cytometry, Western blotting, immunofluorescence and qPCR, in vitro and in mice. Cognitive function was evaluated by behavioural assays using a mouse model of intracerebroventricular infusion of AβO.Key ResultsLASSBio‐1911 modulates reactivity and synaptogenic potential of cultured astrocytes and improves synaptic markers in cultured neurons and in mice. It prevents AβO‐triggered astrocytic reactivity in mice and enhances the neuroprotective potential of astrocytes. LASSBio‐1911 improves behavioural performance and rescues synaptic and memory function in AβO‐infused mice.Conclusion and ImplicationsThese results contribute to unveiling the mechanisms underlying astrocyte role in AD and provide the rationale for using astrocytes as targets to new drugs for AD.
Using ChatGPT for Kidney Transplantation: Perceived Information Quality by Race and Education Levels
Authors: Lee Jihye , Park Jeeyun , Han Hwarang Stephen 
Published: June 2024

ABSTRACTBackgroundKidney transplantation is a complex process requiring extensive preparation and ongoing monitoring. Artificial intelligence (AI)‐powered chatbots hold potential for providing accessible health information, but our understanding of their role in offering health advice for kidney transplantation and how individuals assess such advice remains limited. This study investigates how individuals evaluate ChatGPT's responses to kidney transplantation questions in terms of information quality and empathy, focusing on potential differences across race/ethnicity and educational backgrounds.MethodsWe collected Reddit posts (N = 4624) regarding kidney transplantation and selected 86 questions to represent typical clinician inquiries. These questions were used as input prompts for ChatGPT. A total of 565 participants assessed ChatGPT's responses through online surveys, rating information quality and empathy using Likert scales.ResultsMultilevel analyses (N = 2825) show that there is a significant interaction between race/ethnicity and education levels in various measures related to perceived information quality, but not perceived empathy of ChatGPT's responses: accuracy (p < 0.05); authenticity (p < 0.01); believability (p < 0.05); informativeness (p = 0.053); usefulness (p < 0.05); recognizing users’ feelings (p = 0.70) and understanding feelings and situations (p = 0.65). Among non‐White individuals, higher education levels predicted higher perceived quality of ChatGPT's responses across all information quality measures. Notably, this trend was reversed for White individuals, where higher education levels led to lower perceived information quality.ConclusionsOur results highlight the importance of developing AI tools sensitive to diverse communication styles and information needs.
Validation of the German Pruritus Questionnaire for the systematic assessment of chronic pruritus
Authors: Weisshaar Elke , Kupfer Jörg P. , Bentz Philipp , Staubach‐Renz Petra , Legat Franz , Kremer Andreas E. , Ständer Hartmut , Streit Markus , Darsow Ulf , Mettang Thomas , Ständer Sonja 
Published: June 2024

SummaryBackgroundChronic pruritus is a clinically heterogeneous symptom that manifests itself with varying duration, intensity, or quality. To date, there is no validated German‐language instrument that systematically assesses the relevant parameters. With the support of the Pruritus Research Working Group (Arbeitsgemeinschaft Pruritusforschung, AGP), a questionnaire for the assessment of chronic pruritus (AGP questionnaire) was developed in 2008. The subsequently revised instrument, now called the German Pruritus Questionnaire, records pruritus‐specific parameters such as localization, course, intensity and quality, anamnestic data on the general state of health, sociodemographic data, quality of life, and coping methods. It is to be validated in the study presented here.Patients and methodsThe questionnaire was used in 366 patients with chronic pruritus of different etiologies from Germany (University Hospitals Heidelberg, Münster, Mainz, Erlangen, Giessen, private practice Bad Bentheim, TU Munich, Wiesbaden Kidney Center), Austria (Graz University Hospital) and Switzerland (Aarau Cantonal Hospital).ResultsThe reliability for repeated completion (retest reliability) with regard to localization, first occurrence, and concomitant diseases showed high values for Cohen's kappa (> 0.8). The data on the retest reliability of the pruritus characteristics showed lower values (< 0.7). With regard to the measurability of practically relevant changes (change sensitivity), medium to strong effect sizes were found (0.09–0.19). A statistically significant differentiation of the pruritus etiologies based on the recorded parameters was not possible.ConclusionsThe German Pruritus Questionnaire allows a comprehensive and structured recording of patient‐ and clinician‐reported, relevant dimensions of chronic pruritus of different etiologies. Further adaptation and development are planned.