bluuebunny/crossref_metadata_2025_split huggingface dataset:
Production Analysis of a Shale Gas Reservoir Using Modified Deconvolution Method in the Presence of Sorption Phenomena
Authors: Kim J. , Jang Y. , Ertekin T. , Sung W. M. 
Published: October 2015

Abstract
When analyzing production data during reservoir characterization, pressure transient analysis requires a constant production rate during the entire production period. However, because of the extremely low permeability of shale formations, the flow regime changes over the long period of production. Therefore, it is rarely possible to acquire production data at a constant rate. In addition, as pressure declines with production in a shale gas reservoir, desorption of gas occurs, leading to nonlinearities due to large changes in gas compressibility, and it should be linearized for the use of deconvolution. In this study, we suggest sorption correction for pseudopressure using material balance equation to linearize the pseudopressure–rate relationship. By using this sorption correction term for pseudopressure in the deconvolution, we carried out pressure transient analysis with production data from a shale gas well to obtain the reservoir characteristics. The results show that, without sorption correction, the pseudopressure decline and its derivative varied depending on the magnitude of the desorption. However, with the correction applied, the curves were almost identical regardless of desorption. In the results of the deconvolution analysis with and without the sorption correction, pseudo-linear and pseudo-pseudosteady state flow periods appeared at different times, which explains the anomalous results in the pressure transient analysis. By implementing those results, we analyzed production data acquired from Fayetteville shale. The results show that the reservoir permeability, stimulated reservoir volume, and fracture half-length depended on the use of sorption correction for pseudopressure.
Treatment of Unstable Intertrochanteric Fractureswith Proximal Femoral Nail Antirotation II: Our Experience in Indian Patients§
Authors: Kumar G.N. Kiran , Sharma Gaurav , Khatri Kavin , Farooque Kamran , Lakhotia Devendra , Sharma Vijay , Meena Sanjay 
Published: October 2015

Introduction:Unstable intertrochanteric fractures are difficult to manage and the choice of implant is critical for fracture fixation. The purpose of this study was to evaluate the functional and radiological outcome of proximal femoral nail antirotationII (PFNA II) in the treatment of unstable intertrochanteric fractures.Materials and Methods:We reviewed 45 patients of unstable intertrochanteric fractures, who were treated with the PFNA II between 2011 and 2013. Of which, 3 patients were died within 6 months of follow up. Hence, 42 patients were available for the study including 26 men and 16 women. The mean age was 61 years (range, 35 -90). Clinical evaluation was done using Harris hip score. The position of the blade in the femoral head was evaluated using Cleveland zones and tip apex distance. The fracture reduction was assessed using the Garden Alignment Index and postoperative fracture gap (mm) measurement.Results:The mean follow up period was 15.3 months (range, 9-27). Excellent to good results were accounted for 78% of cases according to Harris hip score. No cases of cut out or breakage of the implant noted. Implant removal was done in 2 patients due to persistent anterior thigh pain.Conclusion:We recommend PFNA II for fixation of unstable intertrochanteric fractures with less operative time and low complication rate. However, proper operative technique is important for achieving fracture stability and to avoid major complications.
Effects on Vitamin D, Bone and the Kidney of Switching from Fixed-Dose Tenofovir Disoproxil Fumarate/Emtricitabine/Efavirenz to Darunavir/ Ritonavir Monotherapy: A Randomized, Controlled Trial (MIDAS)
Authors: Hamzah Lisa , Tiraboschi Juan M , Iveson Helen , Toby Martina , Mant Christine , Cason John , Burling Keith , Wandolo Emily , Jendrulek Isabelle , Taylor Chris , Ibrahim Fowzia , Kulasegaram Ranjababu , Teague Alastair , Post Frank A , Fox Julie 
Published: October 2015

Background Efavirenz (EFV) has been associated with reductions in vitamin D (25[OH]D) and tenofovir (TDF) with increased bone turnover, reductions in bone mineral density (BMD) and renal tubular dysfunction. We hypothesized that switching from fixed-dose TDF/emtricitabine (FTC)/EFV to darunavir/ritonavir monotherapy (DRV/r) might increase 25(OH)D and BMD, and improve renal tubular function. Methods Subjects with HIV RNA <50 copies/ml on TDF/ FTC/EFV for ≥6 months were randomized 1:1 to ongoing TDF/FTC/EFV or DRV/r (800/100 mg once daily) for 48 weeks. The primary end point was change from baseline in 25(OH)D at week 48. Secondary end points included changes in BMD, bone turnover markers and renal tubular function. Results A total of 64 subjects (86% male, 66% white, mean [sd] CD4+ T-cell count 537.3 [191.5]/mm3) were analysed. After adjustment for baseline 25(OH)D and demographics, at week 48 DRV/r monotherapy was associated with a +3.6 (95% CI 0.6, 6.6) ng/ml increase in 25(OH)D compared to TDF/FTC/EFV ( P=0.02). DRV/r monotherapy was associated with an increase in BMD (+2.9% versus -0.003% at the neck of femur and +2.6% versus +0.008% at the lumbar spine for DRV/r versus TDF/FTC/EFV; P<0.05 for all) and reductions in bone biomarkers compared with those remaining on TDF/FTC/EFV. No significant difference in renal tubular function was observed. Reasons for discontinuation in the DRV/r arm included side effects ( n=4) and viral load rebound ( n=3), all of which resolved with DRV/r discontinuation or regimen intensification. Conclusions Switching from TDF/FTC/EFV to DRV/r in patients with suppressed HIV RNA resulted in significant improvements in 25(OH)D and bone biomarkers, and a 2–3% increase in BMD.
Un soutien à la parentalité souvent inadapté aux situations de précarité. L’exemple des foyers monoparentaux
Authors: Neyrand Gérard 
Published: October 2015

La façon dont s’est développé le « soutien à la parentalité » depuis les années 1990 apparaît assez mal adaptée à la situation des plus précaires. L’auteur illustre cette difficulté à partir de l’analyse des foyers monoparentaux, dont aujourd’hui un tiers sont en situation de pauvreté. Pour eux, la précarité est non seulement économique, mais aussi sociale (repli sur soi) relationnelle et psychologique (épisodes dépressifs). Elle suppose une réponse multidimensionnelle, alliant – sur la base d’une formation des intervenants – une écoute personnalisée aidant la mère à l’élaboration de sa situation, articulée à la prise en compte des facteurs matériels : soutien financier et résidentiel, garde de l’enfant, formation qualifiante...
L’intention de quitter l’entreprise : une approche par l’étape de carrière
Authors: Giraud Laurent 
Published: October 2015

Les nombreux modèles de turnover que l’on peut trouver dans la littérature en Gestion des Ressources Humaines illustrent l’importance de la fidélisation des salariés à l’entreprise. L’objectif de cette recherche est d’insérer l’étape de carrière du salarié dans un modèle de turnover classique pour en mesurer l’effet sur ses facteurs de fidélisation. À cette fin, une enquête par questionnaires a été réalisée en janvier 2011 auprès de salariés français d’une entreprise franco-américaine et de deux entreprises françaises. L’échantillon est composé de 478 répondants : 206 vendeurs, 150 techniciens, 76 salariés de fonctions support et 46 de fonctions indéfinies. La population étudiée a un niveau de qualification faible à moyen (CAP/BEP/BAC à BAC+2/BTS). Les données sont analysées à l’aide de la technique des équations structurelles. Les résultats confirment (1) le rôle central de la satisfaction extrinsèque au travail et de l’implication organisationnelle affective dans un modèle de turnover et (2) l’influence du score à l’étape de carrière d’un individu sur les facteurs de fidélisation à l’entreprise. Enfin, le lien entre l’âge ou les différentes formes d’ancienneté et les étapes de carrière n’est pas systématique.
Heur et malheur de l'artiste. Problèmes de souveraineté dans la représentation des vies d'artistes (1780-1820)
Authors: Martin François-René 
Published: October 2015

Les vies des maîtres anciens, enfance, carrière, vie amoureuse, mort, n'ont jamais autant intéressé les artistes et le public qu'au xix e siècle. Derrière la variété des artistes célébrés, c'est le pouvoir de l'artiste qui est en jeu. La reconnaissance du prince ou l'injustice frappant l'artiste constituent deux motifs qui fondent deux conceptions distinctes de la souveraineté de ce dernier. Envahissant le genre anecdotique, ces sujets accèdent parfois au grand genre, la peinture d'histoire, dont ils réinvestissent les codes, les observant ou les subvertissant. L'histoire d'amour entre Raphaël et la Fornarina, telle qu'Ingres l'interprète, donne l'exemple d'une affaire intime rapportée par Vasari qui accède à la dignité d'une histoire où une nouvelle forme de souveraineté de l'artiste vient se définir.
Le corps entier de mon bébé
Authors: Clerget Joël 
Published: October 2015

Le corps du bébé est envisagé dans son rapport à ce qui le constitue dans l’adresse et l’appel du prénom, comme corps d’un sujet. L’intrication du corps et de la psyché permet d’entendre l’intimité existant entre l’environnement et le bébé en mouvement. Le contact assure une portance d’être, par où un enfant rencontre de nombreux autres corps : animal, minéral, végétal… La corporalité s’anime de ce que la vie psychique et pulsionnelle répond de la dynamique symbolique qui nous fait exister.
Le corps du bébé dans l’histoire
Authors: Morel Marie-France 
Published: October 2015

Les écrits familiaux, les représentations d’enfants dans la peinture et les pratiques de puériculture nous montrent que les adultes d’autrefois considéraient le corps des bébés de manière ambivalente. Partageant la sacralité de l’Enfant Jésus, ils deviennent des anges au ciel si le fil fragile de leur vie est rompu. À la naissance, leur corps est considéré comme inachevé et proche de l’animal, ce qui impose des pratiques de façonnage, de contention et de dressage. À partir de la fin du xix e siècle, la médecine pastorienne, en médicalisant la petite enfance, impose une nouvelle puériculture hygiéniste qui change la conception du corps du bébé et fait reculer la mort « évitable ». Depuis les années 1970, les acquis de la psychologie et des neurosciences contribuent à faire du bébé une petite personne individualisée et compétente.
À la découverte de sa corporalité animée
Authors: Xambeu Maurice 
Published: October 2015

Un nouveau-né ne peut découvrir son corps que dans une perception globale de lui-même. La confirmation affective qu’il peut recevoir, dans le contact tendre direct comme dans l’accompagnement de tous ses élans, ses mouvements d’âme, lui permet de découvrir sa façon « d’habiter son corps » : sa corporalité, sentiment qui lui permet de se vivre dans les rencontres.
Housing Temperature–Induced Stress Is Suppressing Murine Graft-versus-Host Disease through β2-Adrenergic Receptor Signaling
Authors: Leigh Nicholas D. , Kokolus Kathleen M. , O’Neill Rachel E. , Du Wei , Eng Jason W.-L. , Qiu Jingxin , Chen George L. , McCarthy Philip L. , Farrar J. David , Cao Xuefang , Repasky Elizabeth A. 
Published: October 2015

Abstract
Graft-versus-host disease (GVHD) is the major complication of allogeneic hematopoietic cell transplantation, a potentially curative therapy for hematologic diseases. It has long been thought that murine bone marrow–derived T cells do not mediate severe GVHD because of their quantity and/or phenotype. During the course of experiments testing the impact of housing temperatures on GVHD, we discovered that this apparent resistance is a function of the relatively cool ambient housing temperature. Murine bone marrow–derived T cells have the ability to mediate severe GVHD in mice housed at a thermoneutral temperature. Specifically, mice housed at Institutional Animal Care and Use Committee–mandated, cool standard temperatures (∼22°C) are more resistant to developing GVHD than are mice housed at thermoneutral temperatures (∼30°C). We learned that the mechanism underlying this housing-dependent immunosuppression is associated with increased norepinephrine production and excessive signaling through β-adrenergic receptor signaling, which is increased when mice are cold stressed. Treatment of mice housed at 22°C with a β2-adrenergic antagonist reverses the norepinephrine-driven suppression of GVHD and yields similar disease to mice housed at 30°C. Conversely, administering a β2-adrenergic agonist decreases GVHD in mice housed at 30°C. In further mechanistic studies using β2-adrenergic receptor–deficient (β2-AR−/−) mice, we found that it is host cell β2-AR signaling that is essential for decreasing GVHD. These data reveal how baseline levels of β-adrenergic receptor signaling can influence murine GVHD and point to the feasibility of manipulation of β2-AR signaling to ameliorate GVHD in the clinical setting.
L’Église-nation canadienne-française au siècle des nationalités : regard croisé sur l’ultramontanisme et le nationalisme
Authors: Laniel Jean-François 
Published: October 2015

L’influence de la doctrine et de la pensée ultramontaines au Canada français, de ses réseaux et de ses luttes politico-religieuses, a fait l’objet de nombreuses recherches. Cependant, l’étude de ses aspects originaux eu égard à la question nationale reste peu explorée. Contrairement à l’ultramontanisme français – monarchiste, critique des Églises nationales et résolument en faveur d’un catholicisme universaliste – sa variante canadienne-française a fait sienne une certaine idée romantique de la nation : l’avènement d’une « contre-société » intégralement catholique s’y est fait projet d’édification nationale. C’est sur cette « affinité élective » entre l’ultramontanisme et le nationalisme canadien-français que porte cet article. En effet, la traduction sociopolitique de l’ultramontanisme mennaisien en sol canadien-français n’est pas sans réserver plusieurs surprises, qu’aident à cerner le rôle providentiel dévolu au peuple et à ses coutumes, son ambition d’institutionnalisation du social et son parti pris farouche pour l’autonomie de l’Église. À ce titre, la pensée « réformiste » d’Étienne Parent, sur laquelle Fernand Ouellet a déjà souligné l’influence des « doctrines théocratiques », exprime ce mélange de nationalisme et d’ultramontanisme, et suggère l’attrait plus large qu’il suscite dans le cadre tumultueux de l’Acte d’Union du Haut et du Bas Canada, puis du « renouveau religieux ». Une telle analyse permet a fortiori de situer le nationalisme canadien-français parmi les types d’édification nationale, ceux des « nations culturelles sans État souverain », où précisément la constitution d’une « Église-nation » est susceptible d’advenir.
Multi-Dimensional Responsible Rural Tourism Capacity (RRTC) Framework: A Proposed Environmental Responsibility and Management Model for Malaysia
Authors: Nair Vikneswaran , Mohamed Badaruddin , Chiun Lo May 
Published: October 2015

AbstractMalaysia is regarded as a heaven for ecotourism and natural resources. Nonetheless, the very concept of ecotourism is confused with massive “greenwashing” that is destroying many pristine destinations especially in the rural settings. Various tourism models emphasising on the environment have been developed in the past in Malaysia with no holistic understanding of their impact to the natural environment. With this challenge in mind, this paper aims to understand and propose an environmental model that is able to balance the natural and economic environment in line with Malaysia’s Economic Transformation Programme where rural tourism is expected to alleviate from a low-yield to a high-yield economy. This will be achieved by developing suitable indicators to make the rural tourism business model sustainable. The first three years of the five year research (2011-2016) were involved in developing the fundamental aspects of the study, with emphasis on the establishment of baseline data and carrying out situational analyses at the ten selected study areas to help develop the indicators. The final two years will evaluate the performance of these sites using the developed indicators. Hence, this fundamental study is necessary to understand the various dimensions that are essential in investigating the relationships between different tourism models and how they are closely linked to the local economies and environments in key “natural” destinations in Malaysia.
Destination Performance: Importance of Redefining DMOs
Authors: Kaurav Rahul Pratap Singh , Baber Ruturaj , Chowdhary Nimit , Kapadia Shakir 
Published: October 2015

AbstractThere is a huge gap in defining the core concept of destination, performance and its marketing / management organisation. This review paper intends to study the aforesaid gap and aid the concept in defining it from different perspectives. The chosen study also highlights the burning need of researchers and students alike in serving the definitional aspect from the literature point of view. The main focus is however on the gaps between defining Destination, Destination Performance and Destination Management / Marketing Organisations (DMOs). We bring in the literature review to define the concepts for today’s scholars as transfiguring for the current tourism industry. In considering the factors affecting the performance of a destination, the research considered eight specific variables i.e., revenue generation, employment generation, investment in tourism-related business, development of basic infrastructure, cultural exchange between tourists and host communities, increasing number of parks and recreational facilities, intra-generational equity and inter-generational equity. These variables were chosen on the merits that make a destination successful in the true sense. The findings also bring insights from the tourism industry to understand better all the key stakeholders. The definitions and model derived can be a supporting pillar for planners and managers of DMOs in crafting a suitable strategy to obtain a better performance from all stakeholders. The main significance of the findings is to help various government departments, agencies, consultancies and NTOs who can visualise and actively use these definitions for policy planning and implementation. This is also a step forward towards regaining the importance of destination with performance, management, marketing and organisation.
Silver Tetrafluoroborate‐Catalyzed Oxa‐Diels–Alder Reaction Between Electrically Neutral Dienes and Aldehydes
Authors: Zou Xiaodong , Yang Lizheng , Liu Xiangli , Sun Hao , Lu Hongjian 
Published: October 2015

AbstractChemoselective oxa‐Diels–Alder reactions between electrically neutral 1,3‐dienes and various aldehydes were achieved using the commercially available silver tetrafluoroborate (AgBF4) as catalyst. This catalytic process has high functional group tolerance. Heteroatoms at the β‐position of the aryl aldehydes can greatly promote the reactivity of the substrates even with heterocyclic aldehydes that were previously believed to be unreactive for the oxa‐Diels–Alder reaction. In addition, acroleins with β‐heteroatom substitution are also good substrates. High chemoselectivity and regioselectivity were achieved at room temperature for the oxa‐Diels–Alder reaction between acroleins and stoichiometric simple 1,3‐dienes.magnified image
Homogeneous Gold‐Catalyzed Cyclization Reactions of Alkynes with N‐ and S‐Nucleophiles
Authors: Debrouwer Wouter , Heugebaert Thomas S. A. , Roman Bart I. , Stevens Christian V. 
Published: October 2015

AbstractThis review covers the formation of N‐ and S‐containing heterocycles, initiated by gold‐catalyzed nucleophilic attack of N‐ or S‐nucleophiles onto alkynes. These types of nucleophiles have been somewhat overlooked as compared to their C‐ or O‐counterparts in other reviews. In this particular work, their intramolecular gold‐mediated attack onto alkynes is reviewed in depth. It is structured in such a fashion that the reader will get a clear view of which substrates react in which cyclization mode.magnified image
Palladium‐Catalyzed Carbonylations of Arylboronic Acids: Synthesis of Arylcarboxylic Acid Ethyl Esters
Authors: Liang Apeng , Han Shuaijun , Wang Liang , Li Jingya , Zou Dapeng , Wu Yangjie , Wu Yusheng 
Published: October 2015

AbstractAn approach for the palladium‐catalyzed ethoxycarbonylations of arylboronic acids using diethyl pyrocarbonate as carbon monoxide/carbon dioxide (CO/CO2) surrogate in moderate to good yields has been investigated.magnified image
Ynones Merge Activation/Conjugate Addition of Chalcogenoborates ArE‐Bpin (E=Se, S)
Authors: Civit Marc G. , Sanz Xavier , Vogels Christopher M. , Bo Carles , Westcott Stephen A. , Fernández Elena 
Published: October 2015

AbstractThe “pull–push” effect of the Bpin moiety in ArE‐Bpin reagents (E=Se, S) is demonstrated by the Lewis acid interaction with the carbonyl group of ynones and the concomitant delivery of ArSe or ArS to the electron‐deficient alkyne with impressive stereoselectivity. The two component reactivity is carried out in methanol to generate (Z)‐β‐(arylseleno)‐α,β‐unsaturated ketones and (Z)‐β‐(arylsulfuro)‐α,β‐unsaturated ketones with a consensus between experimental and theoretical understanding of the mechanism.magnified image
1,5‐Diketones Synthesis via Three‐Component Cascade Reaction
Authors: Xing Li‐Juan , Lu Tao , Fu Wei‐Li , Lou Mei‐Mei , Chen Bo , Wang Zhi‐Shen , Jin Yang , Li Dan , Wang Bin 
Published: October 2015

AbstractA mild and efficient cascade synthesis of 1,5‐diketones from readily available N,N‐dicyclohexylmethylamine, 1,3‐dicarbonyl compounds, and trifluoromethyl β‐diketones has been developed. This cascade reaction occurs via an oxidation/Mannich reaction/Cope elimination/Michael addition/retro‐Claisen reaction sequence, and provides multiple CC bond formations in one pot. In addition, exquisite chemoselectivity is achieved in the reaction between 1,3‐dicarbonyl compounds and trifluoromethyl β‐diketones.magnified image
Enantioselective Michael Addition of Nitroalkanes to Nitroalkenes Catalyzed by Chiral Bifunctional Quinine‐Based Squaramides
Authors: Kanberoğlu Esra , Tanyeli Cihangir 
Published: October 2015

AbstractA family of chiral bifunctional acid‐/base‐type quinine/squaramide organocatalysts is shown to be highly active promoters of the conjugate addition of 1‐nitropropane to various trans‐β‐nitroalkenes. The cooperation of the quinine and the sterically encumbered squaramide moieties catalyzed the Michael addition reactions at 0 °C by using a catalyst loading of only 2 mol % to afford the 1,3‐dinitro Michael adducts with excellent enantioselectivity and diastereoselectivity (up to 95 % ee and syn/anti isomers up to 96:4).
Einfacher Zugang zu α‐Fluoralkylammoniumsalzen
Authors: Baxter Amanda F. , Christe Karl O. , Haiges Ralf 
Published: October 2015

AbstractEine Serie neuartiger α‐Fluoralkylammoniumsalze wurde aus den entsprechenden Cyanverbindungen durch Reaktion mit wasserfreiem HF hergestellt. Raumtemperaturbeständige Trifluormethylammoniumsalze wurden in quantitativer Ausbeute durch eine einfache Reaktion aus den kommerziell verfügbaren Ausgangsverbindungen BrCN und ClCN erhalten. Die neuen Kationen [CF3CF2NH3]+, [HCF2CF2NH3]+ und [(NH3CF2)2]2+ wurden aus HF und CF3CN, HCF2CN bzw. (CN)2 hergestellt. Die genannten fluorierten Ammoniumkationen wurden als bei Raumtemperatur stabile [AsF6]−‐ und/oder [SbF6]−‐Salze isoliert und durch multinukleare NMR‐ sowie Schwingungsspektroskopie charakterisiert. Die Salze [HCF2NH3][AsF6] und [CF3NH3][Sb2F11] wurden zusätzlich durch ihre Röntgenkristallstrukturen charakterisiert.