bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: C—H Bond Functionalization under Metalation—Deprotonation Process: Regioselective Direct Arylation of 3‐Aminoimidazo[1,2‐a]pyrazine.
Authors: Guchhait Sankar K. , Kandekar Somnath , Kashyap Maneesh , Taxak Nikhil , Bharatam Prasad V. 
Published: August 2013

AbstractPd(OAc)2/ PPh3/ PivOH‐mediated treatment of 3‐aminoimidazopyrazines with aryl bromides provides a new and regioselective approach to C6‐arylated derivatives which are of biological interest.
ChemInform Abstract: Synthesis, Design and Biological Evaluation of Novel Highly Potent Tacrine Congeners for the Treatment of Alzheimer′s Disease.
Authors: Hamulakova Slavka , Janovec Ladislav , Hrabinova Martina , Kristian Pavol , Kuca Kamil , Banasova Maria , Imrich Jan 
Published: August 2013

AbstractAmong all the tacrine congeners synthesized, derivative (III) shows the best activity and selectivity against hAChE and derivative (Id) against hBChE.
ChemInform Abstract: 3‐Oxo‐3‐thia‐2‐azabicyclo[2.2.1]hept‐5‐en‐2‐carboxylates: The First Isolation and Characterization.
Authors: Guideri Luca , Ponticelli Fabio 
Published: August 2013

AbstractThe isolation of the instable title compounds is achieved using 0.25 equiv.
ChemInform Abstract: Efficient Synthesis of 3,7‐Diaryl‐1,4‐dihydro[1,2,4]triazolo[5,1‐c][1,2,4]triazines.
Authors: Aiwale Sachin T. , Dallavalle Sabrina 
Published: August 2013

AbstractStarting from 1,2,4‐triazole as the precursor of dibromide (I), a convenient synthesis of triazolotriazine systems is developed.
ChemInform Abstract: The Asymmetric Syntheses of Methyl D‐Digitoxoside (V)/(VI), L‐Oleandrose (X) and L‐Cymarose (XI)/(XII) from Methyl Sorbate, an Achiral Precursor.
Authors: Ono Machiko , Zhao Xi Ying , Kato Keisuke , Akita Hiroyuki 
Published: August 2013

AbstractAsymmetric syntheses of the title carbohydrates (mixtures of pyranoside and furanoside forms in some cases) starting from osmundolactone (I), derived from methyl sorbate, are described.
ChemInform Abstract: Stereoselective Glycosylations by Nitrosyl Tetrafluoroborate‐Catalyzed Activation of Glycosyl Trichloroacetimidate Derivatives.
Authors: Sau Abhijit , Santra Abhishek , Misra Anup Kumar 
Published: August 2013

AbstractThe activation of glycosyl trichloroacetimidates by nitrosyl tetrafluoroborate provides an alternative to existing protocols for the activation of these compounds in multistep oligosaccharide synthesis.
ChemInform Abstract: Structure—Activity Relationship Studies of Natural Product Chemokine Receptor CCR5 Antagonist Anibamine Toward the Development of Novel anti Prostate Cancer Agents.
Authors: Zhang Feng , Arnatt Christopher K. , Haney Kendra M. , Fang Harrison C. , Bajacan John E. , Richardson Amanda C. , Ware Joy L. , Zhang Yan 
Published: August 2013

AbstractDesign, syntheses, and anti prostate cancer activities of new anibamine analogues (I) and (II) are described.
ChemInform Abstract: A New Antifungal and Cytotoxic C‐Methylated Flavone Glycoside from Picea neoveitchii.
Authors: Chen Wei‐Quan , Song Zhi‐Jun , Xu Han‐Hong 
Published: August 2013

AbstractCompound (I) is isolated from the twigs and leaves of Picea neoveitchii Mast together with eight known compounds.
ChemInform Abstract: Phenolic Compounds as Antiangiogenic CMG2 Inhibitors from Costa Rican Endophytic Fungi.
Authors: Cao Shugeng , Cryan Lorna , Habeshian Kaiane A. , Murillo Catalina , Tamayo‐Castillo Giselle , Rogers Michael S. , Clardy Jon 
Published: August 2013

AbstractThe new compounds (I) as well as one known compound are isolated from the endophytic fungus Coccomyces proteae from a Costa Rican rain forest.
ChemInform Abstract: Synthesis and Biological Evaluation of Novel N‐Acyl Substituted Quinolin‐2(1H)‐one Derivatives as Potential Antimicrobial Agents.
Authors: Liu Hong‐Bin , Tang Hui , Yang Dan , Deng Qiao , Yuan Lv‐Jiang , Ji Qing‐Gang 
Published: August 2013

AbstractA series of 13 title compounds of type (I) are prepared and tested for their antibacterial and antifungal activities.
ChemInform Abstract: Discovery of Liver Selective Non‐Steroidal Glucocorticoid Receptor Antagonist as Novel Antidiabetic Agents.
Authors: Shah Kiran , Patel Dipam , Jadav Pradip , Sheikh Mubeen , Sairam Kalapatapu V. V. M. , Joharapurkar Amit , Jain Mukul R. , Bahekar Rajesh 
Published: August 2013

AbstractA series of tertiary amino compounds of type (I) is prepared as non‐steroidal GR antagonists.
ChemInform Abstract: An Overview on Phase Equilibria and Thermodynamic Modeling in Multicomponent Al Alloys: Focusing on the Al‐Cu‐Fe‐Mg‐Mn‐Ni‐Si‐Zn System
Authors: Du Yong , Liu Shuhong , Zhang Lijun , Xu Honghui , Zhao Dongdong , Wang Aijun , Zhou Liangcai 
Published: August 2013

AbstractReview: 143 refs.
ChemInform Abstract: Surface Modification of Light Alloys by Low‐energy High‐current Pulsed Electron Beam
Authors: Zhang X. D. , Hao S. Z. , Grosdidier T. , Zou J. X. , Gao B. , Bolle B. , Allain‐Bonasso N. , Qin Y. , Li X. N. , Dong C. 
Published: August 2013

AbstractReview: 46 refs.
ChemInform Abstract: Transition Metal‐Catalyzed Carbocyclization of Nitrogen and Oxygen‐Tethered 1,n‐Enynes and Diynes: Synthesis of Five or Six‐Membered Heterocyclic Compounds
Authors: Zhang Di‐Han , Zhang Zhen , Shi Min 
Published: August 2013

AbstractReview: 228 refs.
ChemInform Abstract: Spin Entanglement in Supramolecular Systems
Authors: Lorusso G. , Troiani F. , Bellini V. , Ghirri A. , Candini A. , Carretta S. , Santini P. , Amoretti G. , Wernsdorfer W. , Timco G. , et al. et al. 
Published: August 2013

AbstractReview: 55 refs.
Support vector machines combined to observers for fault diagnosis in chemical reactors
Authors: Sheibat‐Othman Nida , Laouti Nassim , Valour Jean‐Pierre , Othman Sami 
Published: August 2013

AbstractA hybrid data/model‐based approach is proposed for fault detection and isolation for chemical reactions in jacketed stirred vessels. Using data‐based methods in high nonlinear systems requires training data to include a wide range of varying operations to ensure correct fault isolation. If such data is not available, a model‐based approach can be used to enhance fault isolation. But, observers require a relatively precise process model, which is also not always available. In this work, we propose to combine an observer with statistical data‐based methods (support vector machines, SVM) for fault detection in order to avoid at the time precise process modelling (necessary for model‐based approach) and great number of training data (necessary for data‐based approach). An interesting case study that falls in this category is a chemical stirred tank reactor, with high nonlinear reactions. Therefore, a simplified process model is used as a starting point to develop an observer for fault isolation. The used process model is corrected using information from SVM when no fault is detected. The methodology is validated experimentally in lab‐scale and pilot‐scale polymerisation reactors. For processes with linear dynamics, model‐free SVM classification was found sufficient to detect and isolate sensor and actuator faults.
Doubly spread preamble sequence for timing acquisition in ultra‐wideband communications
Authors: Jung Sung‐Yoon 
Published: August 2013

SUMMARYWe propose a new preamble that can reduce the performance degradation because of the diminishing of operational complexity in coarse timing acquisition. The reduced‐complexity acquisition algorithm uses a received preamble that has been shortened by summing its elements group‐by‐group. Therefore, the performance deteriorates because it loses the impulsive autocorrelation property of the preamble after summation and correlation. In this paper, we design a preamble sequence with a sliding correlator output function that shows a distinct peak at zero delay and symmetry even after summation based on a flipping and doubly spreading concept. By comparing with other preamble sequences, we prove that the proposed preamble shows better timing acquisition performance in ultra‐wideband channel environment.Copyright © 2013 John Wiley & Sons, Ltd.
Vertebrate whole‐body‐action asymmetries and the evolution of right handedness: A comparison between humans and marine mammals
Authors: MacNeilage Peter F. 
Published: August 2013

AbstractAs part of a vertebrate‐wide trend toward left brain/right side asymmetries in routine whole‐body actions, marine mammals show signs of rightward appendage‐use biases, and short‐ and long‐term turning asymmetries most of which are unique in non‐humans in being just as strong as right handedness, and even stronger than human handedness‐related turning biases. Short‐term marine mammal turning asymmetries and human about‐turning asymmetries share a leading right side, suggesting a commonality in left hemisphere intentional control. The long‐term leftward turning bias that both groups share may be an indirect result of both sensory and motor influences on the right side in dolphins, but be induced by a right‐hemisphere‐controlled spatial/attentional bias to the left in humans. Marine mammals may share, with humans and other higher primates, a left hemisphere specialization for action dynamics, although evidence is currently lacking for human‐like right hemisphere specializations relevant to action in other vertebrates. © 2013 Wiley Periodicals, Inc. Dev Psychobiol 55: 577–587, 2013.
Local differentiation amidst extensive allele sharing in Oryza nivara and O. rufipogon
Authors: Banaticla‐Hilario Maria Celeste N. , van den Berg Ronald G. , Hamilton Nigel Ruaraidh Sackville , McNally Kenneth L. 
Published: August 2013

AbstractGenetic variation patterns within and between species may change along geographic gradients and at different spatial scales. This was revealed by microsatellite data at 29 loci obtained from 119 accessions of three Oryza series Sativae species in Asia Pacific: Oryza nivara Sharma and Shastry, O. rufipogon Griff., and O. meridionalis Ng. Genetic similarities between O. nivara and O. rufipogon across their distribution are evident in the clustering and ordination results and in the large proportion of shared alleles between these taxa. However, local‐level species separation is recognized by Bayesian clustering and neighbor‐joining analyses. At the regional scale, the two species seem more differentiated in South Asia than in Southeast Asia as revealed by FST analysis. The presence of strong gene flow barriers in smaller spatial units is also suggested in the analysis of molecular variance (AMOVA) results where 64% of the genetic variation is contained among populations (as compared to 26% within populations and 10% among species). Oryza nivara (HE = 0.67) exhibits slightly lower diversity and greater population differentiation than O. rufipogon (HE = 0.70). Bayesian inference identified four, and at a finer structural level eight, genetically distinct population groups that correspond to geographic populations within the three taxa. Oryza meridionalis and the Nepalese O. nivara seemed diverged from all the population groups of the series, whereas the Australasian O. rufipogon appeared distinct from the rest of the species.
The Intricate Chemistry of Cobalt(II) Halides and Bis(diphenylphosphanyl)ethane
Authors: Kiefer Gregor , Vrubel Heron , Scopelliti Rosario , Severin Kay 
Published: August 2013

AbstractPhosphane complexes of the putative formula [CoX2(dppe)] [X = Cl, Br, I; dppe = bis(diphenylphosphanyl)ethane] are frequently used catalyst precursors in cobalt‐catalyzed reactions. Despite their widespread use, these complexes have not been structurally characterized. We demonstrate that synthetic procedures for [CoX2(dppe)] afford complexes of the formula [Co4X8(dppe)5] instead. Crystallographic analyses of these complexes reveal an ionic structure with pentacoordinate [CoX(dppe)2]+ cations and a dinuclear [Co2X6(dppe)]2– anion. The bromido and iodido complexes crystallize in two forms, which differ in the geometry of the cation (square‐pyramidal vs trigonal‐bipyramidal).
Synthesis, Structural, and Photophysical Properties of the First Member of the Class of Pyrene‐Based [4]Helicenes
Authors: Hu Jian‐Yong , Feng Xing , Paudel Arjun , Tomiyasu Hirotsugu , Rayhan Ummey , Thuéry Pierre , Elsegood Mark R. J. , Redshaw Carl , Yamato Takehiko 
Published: August 2013

AbstractA convenient route to a new class of pyrene‐based [4]helicenes is presented. Wittig reaction of 7‐tert‐butyl‐1,3‐dimethyl‐5‐formylpyrene with benzyltriphenylphosphonium salts in the presence of nBuLi afforded 7‐tert‐butyl‐1,3‐dimethyl‐5‐(phenylethenyl)pyrenes, from which 4,5‐naphthalene annulated aromatic [4]helicenes, namely 7‐tert‐butyl‐1,3‐dimethyl‐13‐methoxydibenzo[ij,no]tetraphene and 7‐tert‐butyl‐1,3,12,14‐tetramethyldibenzo[ij,no]tetraphene, were obtained by photoinduced intramolecular cyclization. The chemical structures of these [4]helicenes were determined on the basis of their elemental analyses and spectroscopic data. The helicity in the synthesized [4]helicene induced by the presence of the second methyl group in the fjord region is discussed in detail. The photophysical and electrochemical properties of these newly developed [4]helicenes were fully investigated by UV/Vis absorption and photoluminescence spectrphotometry, and cyclic voltammetry (CV), and the crystal structures were determined for two examples.
The Mechanism of Hydrolysis of Aryldiazonium Ions Revisited: Marcus Theory vs. Canonical Variational Transition State Theory
Authors: García Martínez Antonio , de la Moya Cerero Santiago , Osío Barcina José , Moreno Jiménez Florencio , Lora Maroto Beatriz 
Published: August 2013

AbstractSeveral models, theoretical levels and computational methods, all based on the canonical variational transition state approximation, have been used to predict both the experimental activation energies (ΔEexp≠) and the experimental activation free energies (ΔGexp≠) for the hydrolysis of aryldiazonium ions. It is demonstrated that the computation of activation energies (ΔE≠), instead of activation free energies (ΔG≠), agrees better with the corresponding experimental data, showing that the employed computational methods do not afford reliable entropic contributions to the free energy barriers in the case of the studied reaction. However, the most fitted computations of ΔE≠ were not able to clearly differentiate between the mechanisms proposed for this interesting reaction (SN1, SN2 and water cluster). In contrast, the use of the Marcus theory (hyperbolic‐cosine equation) instead of the canonical variational transition state theory leads to excellent agreement between the in‐water‐computed activation energies (ΔEwM≠) and the corresponding ΔEexp≠ values for the SN2 mechanism, but far beyond the limit of error for the SN1 process. The validity of the Marcus theory for the studied SN1 and SN2 reactions is ensured by the fact that both reactions can be described as SET processes. On the other hand, apparently compelling evidence against the SN2 mechanism, such as 13C KIEs and experimental observation of N2 scrambling, are also discussed and alternative explanations are proposed.
Alternate wetting and drying irrigation for rice in Bangladesh: Is it sustainable and has plant breeding something to offer?
Authors: Price Adam H. , Norton Gareth J. , Salt David E. , Ebenhoeh Oliver , Meharg Andrew A. , Meharg Caroline , Islam M. Rafiqul , Sarma Ramen N. , Dasgupta Tapash , Ismail Abdelbagi M. , McNally Kenneth L. , Zhang Hao , Dodd Ian C. , Davies William J. 
Published: August 2013

AbstractThe crop management practice of alternate wetting and drying (AWD) is being promoted by IRRI and the national research and extension program in Bangladesh and other parts of the world as a water‐saving irrigation practice that reduces the environmental impact of dry season rice production through decreased water usage, and potentially increases yield. Evidence is growing that AWD will dramatically reduce the concentration of arsenic in harvested rice grains conferring a third major advantage over permanently flooded dry season rice production. AWD may also increase the concentration of essential dietary micronutrients in the grain. However, three crucial aspects of AWD irrigation require further investigation. First, why is yield generally altered in AWD? Second, is AWD sustainable economically (viability of farmers' livelihoods) and environmentally (aquifer water table heights) over long‐term use? Third, are current cultivars optimized for this irrigation system? This paper describes a multidisciplinary research project that could be conceived which would answer these questions by combining advanced soil biogeochemistry with crop physiology, genomics, and systems biology. The description attempts to show how the breakthroughs in next generation sequencing could be exploited to better utilize local collections of germplasm and identify the molecular mechanisms underlying biological adaptation to the environment within the context of soil chemistry and plant physiology.
Headrace tunnel of the El Alto hydropower project in Panama / Druckstollen des Wasserkraftprojekts El Alto in Panama
Authors: Barwart Christian , Romualdi Paolo , Barioffi Alberto 
Published: August 2013

AbstractThe 3.3 km long headrace tunnel (Lot 2) of El Alto hydropower project in Panama has been tendered as drill and blast excavation. Lot 2 has been arwaded to SELI, Rome/Italy. By using an EPB TBM for tunnel excavation general alignment of tunnel has to be redesigned completely. General and detailed design has been done by viglconsult ZT/Schruns.Internal pressure conditions does allow to use segmetnal ining as final lining most of the tunnel length. Only the last 300m of tunnel does have the requirement of inner lining made of steel. Traditional bar reinforcement has been substitued with steel fibre reinforcement with ductile post crack behaviour. A three‐step grouting programm is foreseen to gain segment stability and is responsible for sealing of the headrace tunnel.Der 3,3 km lange Druckstollen (Baulos 2) des 67 MW Wasserkraftwerkes “El Alto” in Panama wurde als zyklischer Vortrieb ausgeschrieben. Das gegenständliche Baulos wurde als “EPC Contract” an SELI SPA, Rom vergeben. Durch den Einsatz einer EPB TBM mit Tübbingauskleidung bedurfte es einer grundlegenden Umplanung der Trassenführung in Grund und Aufriss. Die generelle sowie Detailplanung wurde von viglconsult ZT aus Schruns durchgeführt.Die Innendruckverhältnisse ließen größtenteils eine nicht “druckhaltende” Auskleidung zu, während die letzten 300 m einer Stahlpanzerung bedurften. Eine spezielle Stahlfaserbewehrung welche mit duktilem Nachrissverhalten ersetze die konventionelle Stabebewehrung in den Tübbingen. Ein dreistufiges Injektionskonzept sorgt für entsprechende Stabilität und Dichtheit des Druckstollens.
Design aspects of the permanent underground infrastructure for the Chuquicamata mine in Chile / Planung der dauerhaften untertägigen Infrastruktur des Bergwerks Chuquicamata in Chile
Authors: Gomes Alexandre R. A. , Reyes Gustavo , Ulloa Juan Carlos 
Published: August 2013

AbstractThe mining complex Chuquicamata, of the National Copper Corporation of Chile (CODELCO), is located in the Atacama Desert, 1, 650 km north of Santiago, and 2, 870 m above sea level. Since the large copper ore reserve that lies below the “Chuquicamata” open pit (Fig. 1) will no longer be economically feasible to mine from the end of this decade, the mine is currently developing the required infrastructure to switch the operation to an underground mine type, where the block caving method with macro‐blocks will be used to mine out copper ore. The future mine will count with four production levels, corresponding to one of the largest underground mining operations in the world, with a production rate of about 140, 000 t/d. This article presents design aspects of the permanent underground infra‐structure works, which encompass several deep and steep tunnels and vertical shafts for the future mine access and operation.Der Bergbaukomplex Chuquicamata der National Copper Corporation of Chile (CODELCO) liegt in der Atacama‐Wüste, 1.650 km nördlich von Santiago und 2.870 m über dem Meeresspiegel (Bild 1). Ab Ende dieses Jahrzehnts wird der Abbau der Lagerstätte im Tagebau nicht mehr wirtschaftlich sein. Daher werden derzeit die notwendigen Infrastrukturanlagen errichtet, um den Betrieb auf Untertagebau umzustellen, wobei das Kupferz im Blockbruchbau mit Makro‐Blöcken abgebaut werden soll.? Das Bergwerk wird künftig über vier Produktionsebenen verfügen und mit einer Produktion von etwa 140.000 t/d zu einem der größten Bergwerken der Welt zählen. Dieser Beitrag stellt einige Planungsgesichtspunkte für die dauerhafte unterirdische Infrastruktur vor, die mehrere tiefliegende und steile Tunnel und Vertikalschächte für die Erschließung der Lagerstätte und den Betrieb des Bergwerks umfasst.
Source terms calculation and atmospheric dispersion for a dynamic release from a CO2 pipeline containing methane and water as impurities
Authors: Esfahanizadeh Leila , Dabir Bahram 
Published: August 2013

AbstractA method for calculating the source terms including values of leak rate, phase fraction, final velocity, and temperature at the position where the leakage jet has expanded to atmospheric pressure from a CO2 pipeline containing impurities (methane and water) is presented with regard to the time‐dependency of the source terms during the leakage. The thermodynamical properties for the mixture are calculated using the Soave‐Redlich‐Kwong equation of state with modified 1st order Huron‐Vidal mixing rule, which is adjustable in PVTsim. The results for the solubility of water in CO2 have shown that this thermodynamic model provides accurate predictions for the mixture properties. The thermodynamic model has been used along with a robust transient two‐phase flow simulator, OLGA, to simulate the leak from the pipeline. Finally, the predicted time‐dependant source terms (Release Rate, Phase Fraction, Final Velocity, and Temperature in the downstream of the leak) were used as input into the dispersion model (UDM) in form of sequential segments.
Intranasal insulin increases regional cerebral blood flow in the insular cortex in men independently of cortisol manipulation
Authors: Schilling Thomas M. , Ferreira de Sá Diana S. , Westerhausen René , Strelzyk Florian , Larra Mauro F. , Hallschmid Manfred , Savaskan Egemen , Oitzl Melly S. , Busch Hans‐Peter , Naumann Ewald , Schächinger Hartmut 
Published: August 2013

AbstractInsulin and cortisol play a key role in the regulation of energy homeostasis, appetite, and satiety. Little is known about the action and interaction of both hormones in brain structures controlling food intake and the processing of neurovisceral signals from the gastrointestinal tract. In this study, we assessed the impact of single and combined application of insulin and cortisol on resting regional cerebral blood flow (rCBF) in the insular cortex. After standardized periods of food restriction, 48 male volunteers were randomly assigned to receive either 40 IU intranasal insulin, 30 mg oral cortisol, both, or neither (placebo). Continuous arterial spin labeling (CASL) sequences were acquired before and after pharmacological treatment. We observed a bilateral, locally distinct rCBF increase after insulin administration in the insular cortex and the putamen. Insulin effects on rCBF were present regardless of whether participants had received cortisol or not. Our results indicate that insulin, but not cortisol, affects blood flow in human brain structures involved in the regulation of eating behavior. Hum Brain Mapp 35:1944–1956, 2014. © 2013 Wiley Periodicals, Inc.