bluuebunny/crossref_metadata_2025_split huggingface dataset:
Airway decision making in major head and neck surgery: Irish multicenter, multidisciplinary recommendations
Authors: Cleere Eoin F. , Read Christopher , Prunty Sarah , Duggan Edel , O'Rourke James , Moore Michael , Vasquez Pedro , Young Orla , Subramaniam Thavakumar , Skinner Liam , Moran Tom , O'Duffy Fergal , Hennessy Anthony , Dias Andrew , Sheahan Patrick , Fitzgerald Conall W. R. , Kinsella John , Lennon Paul , Timon Conrad V. I. , Woods Robbie S. R. , Shine Neville , Curley Gerard F. , O'Neill James P. 
Published: July 2024

AbstractMajor head and neck surgery poses a threat to perioperative airway patency. Adverse airway events are associated with significant morbidity, potentially leading to hypoxic brain injury and even death. Following a review of the literature, recommendations regarding airway management in head and neck surgery were developed with multicenter, multidisciplinary agreement among all Irish head and neck units. Immediate extubation is appropriate in many cases where there is a low risk of adverse airway events. Where a prolonged definitive airway is required, elective tracheostomy provides increased airway security postoperatively while delayed extubation may be appropriate in select cases to reduce postoperative morbidity. Local institutional protocols should be developed to care for a tracheostomy once inserted. We provide guidance on decision making surrounding airway management at time of head and neck surgery. All decisions should be agreed between the operating, anesthetic, and critical care teams.
First detection of multiple cases related to CV‐A16 strain of B1c clade in Beijing in 2022
Authors: Liang Zhichao , Lin Changying , Huo Da , Yang Yang , Feng Zhaomin , Cui Shujuan , Wu Dan , Ren Zhenyong , Li Dan , Jia Lei , Dong Shuaibing , Dou Xiangfeng , Sun Yulan , Gao Zhiyong , Li Renqing 
Published: July 2024

AbstractCoxsackievirus A16 (CV‐A16) is a significant etiologic agent of hand, foot, and mouth disease (HFMD) and herpangina (HA), with the capacity to progress to severe complications, including encephalitis, aseptic meningitis, acute flaccid paralysis, myocarditis, and other critical conditions. Beijing's epidemiological surveillance system, established in 2008, encompasses 29 hospitals and 16 district disease control centers. From 2019 to 2021, the circulation of CV‐A16 was characterized by the co‐circulation of B1a and B1b clades. Multiple cases of HFMD linked to clade B1c has not been reported in Beijing until 2022. This study enrolled 400 HFMD and 493 HA cases. Employing real‐time RT‐PCR, 368 enterovirus‐positive cases were identified, with 180 selected for sequencing. CV‐A16 was detected in 18.89% (34/180) of the cases, second only to CV‐A6, identified in 63.33% (114/180). Full‐length VP1 gene sequences were successfully amplified and sequenced in 22 cases, revealing the presence of clades B1a, B1b, and B1c in 14, 3, and 5 cases, respectively. A cluster of five B1c clade cases occurred between June 29 and July 17, 2022, within a 7‐km diameter region in Shunyi District. Phylogenetic analysis of five complete VP1 gene sequences and two full‐genome sequences revealed close clustering with the 2018 Indian strain (GenBank accession: MH780757.1) within the B1c India branch, with NCBI BLAST results showing over 98% similarity. Comparative sequence analysis identified three unique amino acid variations (P3S, V25A, and I235V). The 2022 Shunyi District HFMD cases represent the first instances of spatiotemporally correlated CV‐A16 B1c clade infections in Beijing, underscoring the necessity for heightened surveillance of B1c clade CV‐A16 in HFMD and HA in this region.
Prospective longitudinal cohort study of quantitative muscle magnetic resonance imaging in a healthy control population
Authors: Forsting Johannes , Rehmann Robert , Rohm Marlena , Kocabas Abdulhadi , De Lorenzo Alice , Güttsches Anne‐Katrin , Vorgerd Matthias , Froeling Martijn , Schlaffke Lara 
Published: July 2024

AbstractQuantitative muscle magnetic resonance imaging (qMRI) is a valuable methodology for assessing muscular injuries and neuromuscular disorders. Notably, muscle diffusion tensor imaging (DTI) gives insights into muscle microstructural and macrostructural characteristics. However, the long‐term reproducibility and robustness of these measurements remain relatively unexplored. The purpose of this prospective longitudinal cohort study was to assess the long‐term robustness and range of variation of qMRI parameters, especially DTI metrics, in the lower extremity muscles of healthy controls under real‐life conditions. Twelve volunteers (seven females, age 44.1 ± 12.1 years, body mass index 23.3 ± 2.0 kg/m2) underwent five leg muscle MRI sessions every 20 ± 4 weeks over a total period of 1.5 years. A multiecho gradient‐echo Dixon‐based sequence, a multiecho spin‐echo T2‐mapping sequence, and a spin‐echo echo planar imaging diffusion‐weighted sequence were acquired bilaterally with a Philips 3‐T Achieva MR System using a 16‐channel torso coil. Fifteen leg muscles were segmented in both lower extremities. qMRI parameters, including fat fraction (FF), water T2 relaxation time, and the diffusion metrics fractional anisotropy (FA) and mean diffusivity (MD), were evaluated. Coefficients of variance (wsCV) and intraclass correlation coefficients (ICCs) were calculated to assess the reproducibility of qMRI parameters. The standard error of measurement (SEM) and the minimal detectable change (MDC) were calculated to determine the range of variation. All tests were applied to all muscles and, subsequently, to each muscle separately. wsCV showed good reproducibility (≤ 10%) for all qMRI parameters in all muscles. The ICCs revealed excellent agreement between time points (FF = 0.980, water T2 = 0.941, FA = 0.952, MD = 0.948). Random measurement errors assessed by SEM and the MDC were low (< 12%). In conclusion, in this study, we showed that qMRI parameters in healthy volunteers living normal lives are stable over 18 months, thereby defining a benchmark for the expected range of variation over time.
Dynamic reciprocal contributions between Indigenous communities and cultural keystone species: A study case in Western Ecuador
Authors: Loayza Gabriela , Pozo Shirley , Lascano Max , Bilhaut Anne‐Gaël , Krainer Anita , Teixidor‐Toneu Irene , Montúfar Rommel 
Published: July 2024

Abstract

The reciprocal contributions concept provides a holistic approach to understanding management of natural resources in social‐ecological systems. The purpose of this study was to understand how Indigenous peoples build reciprocal contributions with cultural keystone species (CKS) through their dynamic knowledge systems.

We explore the cultural value and reciprocal contributions between an endemic palm locally known as tagua (Phytelephas aequatorialis Spruce) and the Indigenous Commune of Salanguillo in western Ecuador. We use a multidisciplinary, mixed methods approach (including participant observation, focus group discussions, talking maps and social surveys) to identify reciprocity at three human dimensions (institutional‐social‐political, biophysical and symbolic–linguistic–cultural).

Our study revealed multiple and diverse reciprocal contributions between people and tagua across all dimensions, and the tagua palm was identified as a CKS. Interactions with tagua reflect broader social‐ecological changes in the region.

Reciprocal contributions between tagua and the Commune are built through direct individual experience, but also rely on communal and national institutional agreements. Integration of Indigenous knowledge with the global environmental discourse underpins the place‐based learning strategies for the sustainable use and management of tagua and human well‐being.

Read the free Plain Language Summary for this article on the Journal blog.
Design of interconnected graphene loaded thermoplastic elastomeric blend composite films for minimizing electromagnetic radiation and efficient heat management
Authors: Ghosh Suman Kumar , Paul Sangit , Ghosh Trisita , Das Narayan Ch. 
Published: July 2024

AbstractIn this work, electrically conductive thermoplastic elastomeric blend composite films based on polystyrene (PS)/ethylene‐co‐methyl acrylate (EMA) filled with functionalized graphene were developed via the solution mixing technique. Morphological analysis revealed that selective localization of amine‐functionalized reduced graphene oxide (G‐ODA) sheets in the EMA phase of co‐continuous binary blend formed a well‐connected dense conductive pathway by graphene sheets ultimately facilitating the double percolation phenomenon. The electrical percolation threshold was achieved at ~2 wt% of G‐ODA loading which was much lower than that for both single polymer composites. An electrical conductivity of 0.9 S/cm was obtained for blend composite film with 10 wt% of graphene concentration whereas for the same filler loading, PS and EMA composites exhibited electrical conductivity of 1.9 × 10−1 and 2.3 × 10−1 S/cm, respectively. The obtained thermal conductivity of the blend composite with 10 wt% of G‐ODA loading was 0.95 W/m K with 400% enhancement compared to the neat blend system. The same composite exhibited increased real and imaginary permittivity of 92 and 83, respectively. The electrical percolation threshold is well‐correlated with the percolation concentration found from storage modulus and thermal conductivity data. The fabricated PS/EMA blend composite film exhibited absorption‐dominant electromagnetic interference SE of −25 and − 35 dB in X‐band frequency (8.2–12.4 GHz) for 10 wt% of graphene loading with a sample thickness of 0.5 and 1 mm, respectively.
SOX9 regulates epithelial‐mesenchymal transformation by mediating the Wnt/β‐catenin signaling pathway in hypospadias
Authors: He Xueyu , Zhang Zhicheng , Liu Zhenmin , Zhang Qiang , Long Chunlan , Shen Lianju , Wei Guanghui , Liu Xing 
Published: July 2024

AbstractThe transcription factor SOX9 is crucial in the development and differentiation of various tissues and cells. However, the roles of SOX9‐dependent genes and pathways in normal urethral development and the mechanism of hypospadias are unclear. This study collected 15 foreskin tissue specimens from patients who underwent hypospadias repair surgery and compared them to normal foreskin tissue specimens obtained during circumcision. The expression levels of SOX9, WNT signaling pathway markers, and epithelial‐mesenchymal transition (EMT) markers were analyzed in both groups. It was found that mRNA and protein levels of SOX9, WNT signaling pathway, and EMT mesenchymal markers were significantly reduced in the hypospadias group compared to the normal foreskin group. In contrast, mRNA and protein levels of epithelial markers were significantly increased in the hypospadias group. Immunofluorescence confirmed the decrease in SOX9 expression. Experiments using siRNA to inhibit SOX9 expression in foreskin fibroblasts yielded similar results to the hypospadias group. The findings suggest that down‐regulation of SOX9 expression may contribute to the development of hypospadias by down‐regulating the WNT pathway and inhibiting EMT. These findings provide new insights into the embryonic development of the urethra.
Improved outcomes of pediatric patients with swallowing disorders through a multidisciplinary dysphagia clinic in a tertiary care children's hospital in Colombia
Authors: Galvis‐Blanco Silvia J. , Martínez‐Moreno Víctor A. , Morales‐Múnera Olga L. , Wilches‐Luna Alejandra , Losada‐Gómez Claudia L. , Palacio‐Petri Silvia , Castañeda‐Agudelo Ángela M. , Rosero‐Vélez Janeth , Torres‐Pérez Leidy J. , Niño‐Serna Laura F. 
Published: July 2024

AbstractMultidisciplinary clinics bring together multiple specialists to care for patients with complex diseases, such as swallowing disorders. Little information exists regarding dysphagia in pediatric patients and its multidisciplinary management in Colombia. This study aimed to characterize patients under the age of 18 with swallowing disorders treated in a multidisciplinary dysphagia clinic at San Vicente Fundacion Hospital in Medellin, Colombia, between 2014 and 2021. A longitudinal, descriptive, observational study with retrospective data collection was conducted. Sociodemographic and clinical data were obtained at three points. A total of 293 patients were included. The most frequent underlying diseases were neurological (mainly cerebral palsy), followed by genetic disorders, with Down syndrome being the most representative. More than 50% of the patients had been hospitalized at least twice for dysphagia. The diagnosis was primarily clinical, supported by a videofluoroscopic swallowing study. The primary prescribed intervention was speech therapy, followed by an alternate feeding route. This study described pediatric patients with swallowing disorders seen in a multidisciplinary clinic. This overview provides healthcare personnel with an understanding of the complexity of swallowing disorders and their relationships to various medical conditions in children.
Green power solutions: Advancements in eco‐friendly cellulose‐derived composite battery separators—Material properties and processing techniques
Authors: Paliwal Rajeev , Kumar Maneesh , Bhatt Hardik B. , Vaya Dipti , Prasad Gayatri , Surolia Praveen K. 
Published: July 2024

AbstractBatteries play a crucial role in our daily lives, with separators being a key component influencing their functionality. The separators based on petrochemical for example polythene and polypropylene have been long favored for their chemical and thermal stability, their drawbacks in terms of sustainability, eco‐efficiency, and associated environmental risks are undeniable. In pursuit of sustainable development, there is a growing demand for biopolymer composite separators that offer a compelling combination of low cost, high mechanical and thermal stability, biodegradability, and renewability. Among these alternatives, cellulose‐derived separators have garnered significant attention from the scientific community. This review delivers a brief overview of cellulose's chemical structure, their types, delving into the intricate interplay of various electrodes and electrolytic solutions. The focus is then directed towards exploring diverse preparatory methods for cellulose‐derived separators, along with highlighting the promising factors associated with their adoption. Special attention is given to cellulose composite separators and the challenges they present.Highlights
Cellulose‐based composite separators in LIB/SIB batteries are discussed.
Preparatory methods for eco‐friendly cellulose‐derived composite battery separators.
Prominent affecting factors of separator performance have been elaborated.
Special attention to the challenges cellulose composite separators present.
Eosinophilic granulomatosis with polyangiitis developed during treatment with benralizmab for severe asthma: A case report and literature review
Authors: Sakabe Mitsukuni , Tobino Kazunori , Obata Yumi , Sogabe Shota , Uchida Kazuki , Murakami Yosuke 
Published: July 2024

AbstractEosinophilic granulomatosis with polyangiitis (EGPA) is a rare autoimmune disorder characterized by necrotizing vasculitis, asthma, and eosinophilia. We report a case of EGPA that developed during benralizumab treatment for severe asthma and provide a literature review. A 79‐year‐old Japanese male with severe asthma presented with generalized purpura 4 months after initiating benralizumab treatment. He had reduced his oral prednisolone dose from 7.5 to 2 mg/day. Laboratory tests revealed eosinophilia, and skin biopsy showed vasculitis with eosinophilic infiltration. He was diagnosed with EGPA and treated with corticosteroids, azathioprine, and mepolizumab, which led to rapid improvement and sustained remission. Five cases of EGPA developing during benralizumab treatment have been reported, with onset ranging from 14 to 36 weeks after initiation. Clinicians should monitor for EGPA development in patients receiving benralizumab, particularly during oral corticosteroid reduction.
Multifunctional Wearable Electronic Based on Fabric Modified by PPy/NiCoAl‐LDH for Energy Storage, Electromagnetic Interference Shielding, and Photothermal Conversion
Authors: Lyu Bin , Chen Ken , Zhu Jiamin , Gao Dangge 
Published: July 2024

AbstractWith the rapid advancement of electronic technology, traditional textiles are challenged to keep up with the demands of wearable electronics. It is anticipated that multifunctional textile‐based electronics incorporating energy storage, electromagnetic interference (EMI) shielding, and photothermal conversion are expected to alleviate this problem. Herein, a multifunctional cotton fabric with hierarchical array structure (PPy/NiCoAl‐LDH/Cotton) is fabricated by the introduction of NiCoAl‐layered double hydroxide (NiCoAl‐LDH) nanosheet arrays on cotton fibers, followed by polymerization and growth of continuous dense polypyrrole (PPy) conductive layers. The multifunctional cotton fabric shows a high specific areal capacitance of 754.72 mF cm−2 at 5 mA cm−2 and maintains a long cycling life (80.95% retention after 1000 cycles). The symmetrical supercapacitor assembled with this fabric achieves an energy density of 20.83 µWh cm−2 and a power density of 0.23 mWcm−2. Moreover, the excellent electromagnetic interference shielding (38.83 dB), photothermal conversion (70.2 °C at 1000 mW cm−2), flexibility and durability are also possess by the multifunctional cotton fabric. Such a multifunctional cotton fabric has great potential for using in new energy, smart electronics, and thermal management applications.
Copper‐Graphene Composite (CGC) Conductors: Synthesis, Microstructure, and Electrical Performance
Authors: Yao Jiali , Kim Chunghwan , Nian Qiong , Kang Wonmo 
Published: July 2024

AbstractImproving the electrical performance of copper, the most widely used electrical conductor in the world is of vital importance to the progress of key technologies, including electric vehicles, portable devices, renewable energy, and power grids. Copper‐graphene composite (CGC) stands out as the most promising candidate for high‐performance electrical conductor applications. This can be attributed to the superior properties of graphene fillers embedded in CGC, including excellent electrical and thermal conductivity, corrosion resistance, and high mechanical strength. This review highlights the recent progress of CGC conductors, including their fabrication processes, electrical performances, mechanisms of copper‐graphene interplay, and potential applications.
A Janus Microsphere Delivery System Orchestrates Immunomodulation and Osteoinduction by Fine‐tuning Release Profiles
Authors: Shi Yang , Gu Jingyi , Zhang Chun , Mi Rui , Ke Zhiwei , Xie Mingjun , Jin Wenjing , Shao Changyu , He Yong , Shi Jue , Xie Zhijian 
Published: July 2024

AbstractBone regeneration is a well‐orchestrated process synergistically involving inflammation, angiogenesis, and osteogenesis. Therefore, an effective bone graft should be designed to target multiple molecular events and biological demands during the bone healing process. In this study, a biodegradable gelatin methacryloyl (GelMA)‐based Janus microsphere delivery system containing calcium phosphate oligomer (CPO) and bone morphogenetic protein‐2 (BMP‐2) is developed based on natural biological events. The exceptional adjustability of GelMA facilitates the controlled release and on‐demand application of biomolecules, and optimized delivery profiles of CPO and BMP‐2 are explored. The sustained release of CPO during the initial healing stages contributes to early immunomodulation and promotes mineralization in the late stage. Meanwhile, the administration of BMP‐2 at a relatively high concentration within the therapeutic range enhances the osteoinductive property. This delivery system, with fine‐tuned release patterns, induces M2 macrophage polarization and creates a conducive immuno‐microenvironment, which in turn facilitates effective bone regeneration in vivo. Collectively, this study proposes a bottom‐up concept, aiming to develop a user‐friendly and easily controlled delivery system targeting individual biological events, which may offer a new perspective on developing function‐optimized biomaterials for clinical use.
Insight into Fluoride Additives to Enhance Ammonia Production from Lithium‐Mediated Electrochemical Nitrogen Reduction Reaction
Authors: Shin Dongwoo , Jeon Yeongbae , Nguyen Vy Thuy , Kang Shinmyeong , Hong Yewon , Lim Chaeeun , Yong Kijung , Shin Hyeyoung , Hwang Yun Jeong 
Published: July 2024

AbstractDemands for green ammonia production increase due to its application as a proton carrier, and recent achievements in electrochemical Li‐mediated nitrogen reduction reactions (Li‐NRRs) show promising reliability. Here, it is demonstrated that F‐containing additives in the electrolyte improve ammonia production by modulating the solid electrolyte interphase (SEI). It is suggested that the anionic additives with low lowest unoccupied molecular orbital levels enhance efficiency by contributing to the formation of a conductive SEI incorporated with LiF. Specifically, as little as 0.3 wt.% of BF4− additive to the electrolyte, the Faradaic efficiency (FE) for ammonia production is enhanced by over 15% compared to an additive‐free electrolyte, achieving a high yield of 161 ± 3 nmol s−1 cm−2. The BF4− additive exhibits advantages, with decreased overpotential and improved FE, compared to its use as the bulk electrolyte. The observation of the Li3N upper layer implies that active Li‐NRR catalytic cycles are occurring on the outermost SEI, and density functional theory simulations propose that an SEI incorporated with LiF facilitates energy profiles for the protonation by adjusting the binding energies of the intermediates compared to bare copper. This study unlocks the potential of additives and offers insights into the SEIs for efficient Li‐NRRs.
Multiple associated fibroepithelial polyps (acrochordonous plaques) in the external ear canal of three French bulldogs with chronic otitis
Authors: Mendes Carolina , Nordio Laura , De Lucia Michela 
Published: July 2024

AbstractMultiple closely associated fibroepithelial polyps, also known as acrochordonous plaques, are benign proliferative lesions, described so far only on the dorsal neck and the head of bulldogs and pugs, and on the lumbo‐sacral region of a dobermann. Here, we report for the first time the presence of multiple closely associated fibroepithelial polyps in the external ear canal of three French bulldogs with chronic otitis. In all the cases, lesions presented as a plaque composed of domed shaped, villous or filiform proliferations. The diagnosis was obtained combining video‐otoscopic and histopathological findings. In only one case, these lesions were considered critical for the persistence of the otitis externa, and surgical treatment was recommended. Multiple closely associated fibroepithelial polyps should be set among the differential diagnoses of plaque‐like lesions with an irregular surface in the external ear canal of French bulldogs.