bluuebunny/crossref_metadata_2025_split huggingface dataset:
Electret‐Inspired Charge‐Injected Hydrogel for Scar‐Free Healing of Bacterially Infected Burns Through Bioelectrical Stimulation and Immune Modulation
Authors: Liu Mujie , Wang Yuheng , Wang Haodong , Qi Lihong , Shang Yuxuan , Song Jiajie , Feng Xiulong , Chen Yiwei , Memon Waqar Ali , Shen Yuping , Wu Xiaodong , Cao Jiangbei , Zhao Yifan , Jiang Zhuangde , Liu Dingxin , Shafique Shareen , Li Shengtao , Lu Guanghao , Wei Zhixiang , Liu Zhijie , Zhou Kun , Quan Yuping , Zhang Xiaoyu , Zou Xin , Wang Xuefeng , Liu Na , Zhang Yaqing , Hu Yiwei , Han Chao , Wang Wen 
Published: February 2025

AbstractIn this study, an electret‐inspired, charge‐injected hydrogel called QOSP hydrogel (QCS/OD/SDI/PANI/PS/Plasma) that promotes scar‐free healing of bacteria‐infected burns through bioelectrical stimulation and immune modulation, is presented. The hydrogel, composed of quaternized chitosan (QCS), oxidized dextran (OD), sulfadiazine (SDI), polystyrene (PS), and polyaniline nanowires (PANI), forms a conductive network capable of storing and releasing electric charges, emulating an electret‐like mechanism. This structure delivers bioelectrical signals continuously, enhancing wound healing by regulating immune responses and minimizing fibrosis. In a mouse model of second‐degree burns infected with Staphylococcus aureus (SA) and Pseudomonas aeruginosa (PA), the hydrogel accelerates wound healing by 32% and reduces bacterial load by 60%, significantly inhibited scar formation by 40% compared to controls. QOSP hydrogel modulates the Th1/Th2 immune balance toward a Th1‐dominant antifibrotic state through quaternized chitosan, thereby reducing collagen deposition by 35%. Electro‐dielectric characterization reveals a dielectric constant of 6.2, a 34% improvement in conductivity (3.33 × 10−5 S/m) and a 30 °C increase in thermal stability. Proteomic analysis highlights a 50% down‐regulation of pro‐inflammatory and pro‐fibrotic pathways, suggesting a controlled immune response conducive to scar‐free healing. This study underscores the potential of bioelectrically active hydrogels as a novel approach for treating infected wounds prone to scarring.
Perillaldehyde Improves Parkinson‐Like Deficits by Targeting G3BP Mediated Stress Granule Assembly in Preclinical Models
Authors: Fang Minglv , Luo Lingling , Chen Youjia , Liu Ying , Yan Yingxuan , Wang Fei , Zou Yan , Zhu Huanhu , Wu Xiaojun , Jin Zhigang , Huang Cheng , Zhang Yu , Fan Shengjie 
Published: February 2025

AbstractStress granules (SGs) fulfill a pivotal role in host defense mechanisms, by sequestering both mRNA and protein via the process of liquid–liquid phase separation (LLPS). In this study, we showed that perillaldehyde (PAE), a natural occurring compound, bound directly to the core protein of SGs, Ras GTPase‐activating protein‐binding protein 1/2 (G3BP1/2), thereby inducing the assembly of SGs through the LLPS of G3BP/RNA complexes in vitro. Moreover, in Parkinson's disease (PD) models using Caenorhabditis elegans (C. elegans) and mice, PAE administration prompted SG formation, enhanced eIF2α phosphorylation, shielded dopaminergic neurons from toxic insults, mitigated α‐synuclein (α‐syn) aggregation, and improved PD‐like motor disorders. In addition, these findings revealed that the interaction between G3BP1 and histone deacetylase 6 (HDAC6) inhibited the functions of cytoplasmic HDAC6 and reduced α‐syn aggregation in cells and worms. Notably, the inhibition of SG assembly via gtbp‐1 and tiar‐1 RNAi effectively counteracted the beneficial effects of PAE in C. elegans. Collectively, these results imply that PAE may exert neuroprotective effects by targeting G3BP‐mediated SG formation, thereby safeguarding dopaminergic neurons from toxic damage.
Mechanical Compatibility in Stitch Configuration and Sensor Adhesion for High‐Fidelity Pulse Wave Monitoring
Authors: Chen Zhongda , Song Jun , Lu Yu , Zhu Jing , Zhu Hongxu , Du Wenxian , Hu Benhui 
Published: February 2025

AbstractWearable electronics can achieve high‐fidelity monitoring of pulse waveforms on the body surface enabling early diagnosis of cardiovascular diseases (CVDs). Textile‐based wearable devices offer advantages in terms of high permeability and comfort. However, knitted strain sensors struggle to capture small‐range deformation signals due to stress dissipation during friction and slip of yarns within the textiles. They are optimized for mechanical adaptability and adhesive capability. In this work, the stitch configurations of knitted structure are adjusted to optimize the energy dissipation ratio during deformation and waveform fitting performance. These electric‐mechanical results enabled the selection of the most suitable knitted structure for the clinical diagnosis. On the other hand, the sensor's adhesion is optimized with respect to electrical‐force‐strain coupling and energy transfer efficiency at the interface between skin and sensor. The balance between the storage modulus and loss modulus are adjusted via the crosslinking degree of the polyacrylamide (PAAm) hydrogel network. As a result, the optimized knitted sensor enables stable collection of pulse waveforms from the radial and dorsalis pedis arteries. In human patient evaluations, the knitting‐based strain sensor can distinguish patients with different potential CVD risks through extracted characteristic indicators.
Supramolecular Interaction‐Driven Amorphization of Poly(aryl piperidine) Membranes for Enhanced Proton Conductivity
Authors: Cheng Qianqian , Sheng Zutao , Li Mingjie , Ye Wenjing , Peng Sangshan , Zeng Guang , He Qing 
Published: February 2025

AbstractNon‐fluorinated polymer membranes offer a commercially feasible solution for redox flow batteries (RFBs), yet their practical applications have been hampered by inherent challenges such as chemical instability and low ionic conductivity. In this study, the development of a series of ether‐bond‐free poly(aryl piperidine) membranes that address these limitations by introducing enhanced disorder in polymer chain packing through supramolecular interactions with organic acids, is presented. These interactions effectively disrupt densely packed polymer chains, transforming proton‐inaccessible crystalline regions into accessible amorphous ones. By eliminating chemically unstable aryl ether bonds and avoiding additional chemical modifications, these membranes exhibit remarkable long‐term chemical stability. The presence of abundant interchain gaps further facilitates rapid proton‐selective transport. As a result, the engineered membranes demonstrate sustained performance in vanadium RFBs, maintaining stable operation for over 1000 charge/discharge cycles, and achieving an impressive energy efficiency of 80% at a high current density of 280 mA cm−2. The combination of experimental data and theoretical modeling suggests that the membrane's outstanding performance arises from the interconnected and widely distributed interchain gaps, which exhibit a pore‐limiting diameter of ≈8 Å. These findings offer a robust design strategy for developing chemically stable, high‐performance non‐fluorinated membranes for RFBs and related energy conversion devices.
Earnings Call Scripts Generation With Large Language Models Using Few‐Shot Learning Prompt Engineering and Fine‐Tuning Methods
Authors: Nath Sovik Kumar , Zhang Yanyan , Li Jia Vivian 
Published: February 2025

ABSTRACTCompany earnings calls are pivotal events that offer crucial insights into a company's financial well‐being and future outlook. Large language models (LLMs) present a promising avenue for automatically generating the initial draft of earnings call scripts, leveraging financial data and past examples. We evaluate two distinct methods: (1) few‐shot learning prompt engineering with a large language model (LLM) and (2) fine‐tuning a large language model on earnings call transcript data. Our findings indicate that both methods can produce coherent scripts encompassing key metrics, updates, and guidance. However, there are inherent trade‐offs in comprehensiveness, potential hallucinations, writing style, ease of use, and cost. We discuss the pros and cons of each method to guide practitioners on effectively harnessing LLMs for earnings call script generation. Notably, we employ a human and two different LLMs to act as judges to compare the outcomes generated by the two approaches.
Quorum quenching enzymes disrupt bacterial communication in a sex‐ and dose‐dependent manner
Authors: Syal Aneesh , Martell Maria , Sikdar Rakesh , Dietz Matthew , Ziegert Zachary , Jahansouz Cyrus , Elias Mikael H. , Staley Christopher 
Published: February 2025

AbstractBackgroundOver the past 50 years, the incidence of obesity has gradually increased, necessitating investigation into the multifactorial contributors to this disease, including the gut microbiota. Bacteria within the human gut microbiome communicate using a density‐dependent process known as quorum sensing (QS), in which autoinducer (AI) molecules (e.g., N‐acyl‐homoserine lactones [AHLs]) are produced to enable bacterial interactions and regulate gene expression.MethodsWe aimed to disrupt QS using quorum quenching (QQ) lactonases GcL and SsoPox, which cleave AHL signaling molecules in a taxa‐specific manner based on differing enzyme affinities for different substrates. We hypothesized that QQ hinders signals from obesity‐associated pathobionts, thereby slowing or preventing obesity.ResultsIn a murine model of diet‐induced obesity, we observed GcL and SsoPox treatments have separate sex‐dependent and dose‐dependent effects on intestinal community composition and diversity. Notably, male mice given 2 mg/mL SsoPox exhibited significant changes in the relative abundances of gram‐negative taxa, including Porphyromonadaceae, Akkermansiaceae, Muribaculaceae, and Bacteroidales (Kruskal–Wallis p < 0.001). Additionally, we used covariance matrix network analysis to model bacterial taxa co‐occurrence due to QQ enzyme administration. There were more associations among taxa in control mice, particularly among gram‐negative bacteria, whereas mice receiving SsoPox had the fewest associations.ConclusionsOverall, our study establishes proof of concept that QQ is a targetable strategy for microbial control in vivo. Further characterization and dosage optimization of QQ enzymes are necessary to harness their therapeutic capability for the treatment of chronic microbial‐associated diseases.
Fabrication and Characterization of Polyester Fabric Surface‐Coated Indium Tin Oxide for Infrared Shielding Application
Authors: Chen Yida , Liu Yidan , Guo Shengnan , Ma Mingbo , Zhou Wenlong 
Published: February 2025

ABSTRACTIndium tin oxide (ITO) has attracted considerable in optoelectronics for wide bandgap, high conductivity, and infrared reflectance. Herein, 800 nm ITO films were deposited on common polyester fabric using radio frequency (RF) magnetron sputtering to prepare durable infrared stealth polyester textiles. The prepared ITO films deposited fabric surface exhibited an emissivity of 0.38 in the 8–14 μm range, indicating infrared stealth performance. Additionally, the solar shielding ability in the 0.8–1.6 μm range was improved by 50%. The X‐ray diffractometer (XRD) and high‐resolution transmission electron microscope (HRTEM) results show the desired (400) crystalline plane of the ITO film. Scanning electron microscopy (SEM) images reveal a triangular cone‐shaped granular morphology on the film's surface. Significantly, The ITO coating adhered well to the polyester, showing no peeling after 12 domestic washes, despite some friction damage, and maintaining its infrared stealth performance. Moreover, the hand feel, tensile strength, and breathability of the fabric were not significantly affected by ITO coating, while improvements were observed in the fabric's water repellency, antistatic properties, and UV resistance. This study demonstrates that controlled RF magnetron sputtering can be used to fabricate durable ITO/polyester composites with infrared stealth properties and high‐performance wearability, offering a practical approach for advanced textile applications.
Phytic Acid/Sodium Alginate Coating to Enhance Flame Retardancy of Rigid Polyurethane Foam: A Novel Strategy for Fire Safety
Authors: Wang Hao , Lin Yongquan , Sun Junjie , Wang Xin , Yu Hailong , Deng Kai , Zeng Rong , He Minghai , Tang Gang , Tao Congxi 
Published: February 2025

ABSTRACTThe precursor composed of phytic acid (PA) and sodium alginate (SA) was fabricated using the sol–gel technique and subsequently applied as a coating on the surface of rigid polyurethane foam (RPUF). PA/SA aerogel was obtained using freeze‐drying technology to enhance the fire resistance and flame‐retardant properties of the RPUF. Subsequent testing revealed that a 0.5 mm thick aerogel coating effectively enhances the flame retardancy of the composite. Limiting oxygen index (LOI) of the composites stands at an impressive 30.4 vol%, and it attains the V‐0 rating in UL‐94 vertical combustion testing. The Peak heat release rate (PHRR) measures 356.62 kW/m2, indicating a 27.60% reduction compared to that of pure RPUF. Thermogravimetric analysis shows a residual char residue of 20.78 wt%, representing a 52.46% increase compared to the pristine sample. Parameters such as the PHRR and fire growth index (FGI) exhibit significant reductions. This novel aerogel coating significantly enhances the fire safety of RPUF, effectively broadening applications of RPUF.
Study on Modified EBIR With Improving Filler Dispersion and Mechanical Properties of Filler‐Rubber Composites
Authors: Wang Yixiao , Zhu Guangqian , Hou Xiaogeng , Qin Bao , Wang Keqiang , Sui Feifei , Xu Guangqiang , Wang Qinggang , Hou Hongbin , Zhang Liang 
Published: February 2025

ABSTRACTEpoxidized butadiene‐isoprene rubber (EBIR) holds promising application prospects in high performance tires. However, there have been relatively few advancements in EBIR‐based composites so far, primarily due to challenges in fillers dispersion and rubber compatibility. A class of epoxidized butadiene‐isoprene rubber (EBIR) was developed through in situ epoxidation, and the application of the modified EBIR was also explored as a macromolecular compatilizer in the silica/BIR/BR composites system. The incorporation of highly epoxidized EBIR significantly increased the bound rubber content, improved interface interaction between silica and rubber, consequently lower Payne effect of the rubber composites, as observed with the rubber processing analyzer (RPA). Mechanical property characterization showed that the composites' tear strength and wear resistance were increased by 65.2% and 42.3% respectively when adding 9 phr EBIR, and the wet‐skid resistance was promoted by 27.3% by the dynamic mechanical analysis (DMA).
Overexpression of Acetylation‐Defective Heat Shock Protein 60 Inhibits the Proliferation of Nucleopolyhedrovirus in Bombyx mori
Authors: Li Yao , Wu Jiannan , You Yi , Miao Meng , Yu Wei 
Published: February 2025

ABSTRACTHeat shock protein 60 (Hsp60), abundantly presents in mitochondria, is a highly conserved chaperone that maintains the stability and functionality of mitochondrial proteins, while also participating in the regulation of various cellular processes. As a member of the heat shock family, Hsp60 significantly influences viral proliferation. However, limited research is available on its role in the proliferation of entomopathogenic baculoviruses, particularly Bombyx mori nucleopolyhedrovirus (BmNPV). Our previous proteomics results showed a significant decrease of Hsp60 acetylation levels after BmNPV infection. To investigate the impact of Hsp60 deacetylation on viral proliferation, site‐direct mutagenesis was performed to generate a deacetylated (K/R) mimic of Hsp60. We found that the acetylation level of lysine 362 (K362) decreased after BmNPV challenge. Furthermore, overexpression of deacetylation‐mimicking Hsp60 reduced the chaperone activity of Hsp60, leading to impaired mitochondrial function, including increased reactive oxygen species (ROS) levels, decreased mitochondrial membrane potential, and reduced substrate protein Manganese‐containing superoxide dismutase (Mn‐SOD) activities, ultimately leading to inhibition of viral proliferation. This study establishes lysine 362 acetylation of Hsp60 as a model for Posttranslational modifications induced by host‐virus interactions, providing new insights into potential antiviral strategies.
The Impact of Affective Theory of Mind on Autistic Individual's Perception of Remorse
Authors: Tan Qi Sheng , Weber Nathan , Lim Alliyza , Young Robyn L. 
Published: February 2025

ABSTRACTPrevious research indicates that difficulties with expressing remorse may contribute to the longer sentences autistic individuals receive within the criminal justice system. These differences in remorse expression may stem from their reduced ability to perceive emotions in others. This study investigated the association between an individual's level of autistic traits and their remorse perception ability. We also examined the influence of Affective Theory of Mind (ToM), the ability to understand others' emotional experiences, in remorse perception. We thought that the more autistic traits with which a person presented, the poorer their ability to perceive remorse would be, with overall ToM and affective ToM serving as mediating factors. Forty‐five autistic and 47 non‐autistic individuals assessed a series of facial expressions to determine the perceived level of remorse in each face. Results revealed that neither the combination of autistic traits nor any individual trait was significantly correlated with remorse perception ability. Additionally, autistic traits did not indirectly impact the perception of remorse through either overall ToM or affective ToM. These findings imply that individuals with high autistic traits, regardless of their perspective‐taking abilities, exhibit similar capacities for perceiving remorseful expressions to those with less autistic traits—at least when the stimuli are static. Future research should investigate the differences between autistic and non‐autistic individuals in perceiving remorse through different modalities of emotional expression, including behavioral and verbal cues.
Origanum Essential Oil and Antifungal Activity: A Systematic Review
Authors: Mezzomo Leticia , Butzge Juliana , Fiorio Mariana , Bastian Caroline , Mezzari† Adelina , Fuentefria Alexandre , Anders Apel Miriam 
Published: February 2025

Fungi are pathogens that affect humans, animals, food and plants. Many strains are resistant to currently available antifungals, which are also associated with high toxicity and can cause environmental pollution. Treatments are lengthy with low adherence rates. Given plant´s historical use in disease treatment, natural products, such as essential oils,have been studied and developed for fungal infection treatment. Therefore, the aim of this study was to conduct a systematic literature review on Origanum species commercialized in Brazil: Origanum compactum, O. minutiflorum, O. syriacum, and O. vulgare, focusing on the chemical composition of their oils and their antifungal activity. A systematic literature review was conducted following PRISMA guidelines, using the databases ScienceDirect, Scielo, PubMed, Scopus, and Web of Science. O. vulgare presented the highest number of articles, and O. compactum showed the best results in terms of MIC and against the evaluated fungal species. Candida spp., Aspergillus spp., and Penicillium spp. were the most studied fungi. Carvacrol, thymol, p‐cymene, o‐cymene, and γ‐terpinene are key constituents linked to their antifungal effects. The findings of this review highlight the chemical diversity of the studied genera and underscore the potential of Origanum spp.essential oils as antifungal agents against a variety of fungi.
Factors Associated With ESG Investment Attitude
Authors: Dinh Van , Xiao Jing Jian 
Published: February 2025

ABSTRACTIn recent years, Environmental, Social, and Governance (ESG) oriented investments have grown significantly in terms of volume and influence within the global financial markets. However, there is also a notable countertrend against ESG investments in certain regions and sectors, driven by skepticism around ESG performance, regulatory concerns, and political opposition. Therefore, understanding factors that drive investor attitude towards these ESG assets is crucial. Using data from National Financial Capability Study (NFCS) in 2021, this study delved into exploring factors, specifically values, investment experience, and investment knowledge, that are correlated the ESG investment attitude of US investors. Findings showed that while valuing social responsibility was positively, extensive investment experience was negatively associated with ESG investment attitude. In addition, subjective investment knowledge was positively, while objective investment knowledge was negatively associated with ESG investment attitude. These factors collectively predicted 39% of the variability in ESG investment attitude. These findings highlighted the complex interaction among investment values, experience, and knowledge in determining individual attitudes towards ESG investment. The study implies the need for enhanced investor education on ESG issues and in designing strategies related to investment diversification, including ESG assets.
Artificial Intelligence‐Assisted Experimental Optimization of Water Oxidation Catalysts
Authors: Spitzenpfeil Henrik , Neumann Marius , Hausen Nick , Palkovits Regina , Palkovits Stefan 
Published: February 2025

AbstractArtificial intelligence (AI) methods are very often used to make predictions for datasets that were created externally in arbitrary experiments or on already literature known datasets. In this work, we try to make use of active learning techniques to search for an optimal strategy for the startup‐phase of bulk nickel electrodes in the oxygen evolution reaction. The data collected was afterwards reduced in dimensions and used to extract additional information that were learned via an artificial neural network (ANN) on the dataset, respectively.
Development of a bio‐xerogel from Kraft black liquor and tannin: Crosslinker analysis and property assessment
Authors: Moreira Wardleison Martins , Viotti Paula Valéria , Paschoal Sirlei Marques , dos Santos Gaudêncio Baptista Cristina Maria , Gimenes Marcelino Luiz 
Published: February 2025

AbstractThe increasing environmental impact of industrial waste has driven the search for new synthesis routes utilizing natural precursors. This study explores the production of a biobased polymer from crude Kraft black liquor and condensed tannin, crosslinked with less toxic aldehydes such as furfural and glyoxal, as alternatives to formaldehyde. The synthesized bio‐xerogels demonstrated varying viscosities and physical properties depending on the tannin content and type of crosslinker used. Results indicated that furfural‐based formulations successfully gelled and exhibited superior mechanical strength and stability compared to formaldehyde ones. The study highlights the feasibility of using lignin‐rich industrial by‐products and natural phenolic compounds to develop sustainable, high‐performance materials. This contributes to achieving sustainable development goals (SDGs) and offers potential applications in various environmental, medical, and industrial sectors.