bluuebunny/crossref_metadata_2025_split huggingface dataset:
Scale-Up and Control of the Acrylamide Polymerization Process in Solution
Authors: Mil-Martínez Rubén , Gómez-López Aldo , Escandón Juan P. , Jimenez Edson M. , Martínez-Suástegui Lorenzo , Vargas René O. 
Published: August 2024

The scale-up and control of the acrylamide polymerization process in solution is presented. The viscosity is modeled as a function of temperature and monomer concentration. Four cases are analyzed: (i) Keeping the similarity principles to carry out the polymerization using water to heat and cool the process, (ii) using water with nanoparticles to heat and cool the process, (iii) adding the initiator at different temperatures to start the polymerization, and (iv) modifying the heat-transfer area by changing the aspect ratio L/Dr. The reactor and jacket temperature profiles, the reaction conversion, and the average molecular weight are presented. The main finding is that increasing the heat-transfer area by modifying the L/Dr ratio also increases the efficiency of the polymerization process. Futhermore, the numerical results indicate that the addition of the initiator at low temperatures increases the molecular weight of the final product.
Modifiable Factors Associated with Prolonged Dialysis Recovery Time and Fatigue in Hemodialysis Patients
Authors: Aoun Mabel , Laruelle Eric , Duneau Gabrielle , Duquennoy Simon , Legendre Bruno , Baluta Simona , Maroun Thérèse , Lamri Aldjia , Gosselin Morgane , Chemouny Jonathan , Champtiaux-Dechamps Béatrice , Baleynaud Juliette , Le Mouellic Lionel , Bellier Céline , Gritti Marion , Cain Claire , Hervé Juliette , Colin Pauline , Fleury Sandrine , Floch Christel , Jousset Philippe , Dolley-Hitze Thibault 
Published: August 2024

Key Points

A negative change in serum sodium during a dialysis session is an independent factor associated with prolonged dialysis recovery time.Lower hemoglobin is an independent factor associated with fatigue in hemodialysis patients.Hemodiafiltration use in patients age ≥85 years is associated with a longer dialysis recovery time.

Background
Dialysis recovery time (DRT) and fatigue are two important patient-reported outcomes that highly affect hemodialysis patients' well-being and survival. This study aimed to identify all modifiable dialysis-related factors, associated with DRT and fatigue, that could be addressed in future clinical trials.

Methods
This multicenter observational study included adult patients, undergoing chronic hemodialysis for >3 months during December 2023. Patients admitted to hospital, with cognitive problems or active cancer were excluded. DRT was determined by asking over six sessions: How long did it take you to recover from your last dialysis session? Fatigue was assessed using the French-validated Standardized Outcomes in Nephrology-Hemodialysis fatigue scale. Logistic regression analysis assessed the association between DRT >12 hours and fatigue score ≥4 with all dialysis-related factors. A subanalysis of DRT-related factors was performed for very elderly patients aged 85 years and above.

Results
A total of 536 patients and 2967 sessions were analyzed. The mean age was 68.1±14.3 years, 60.9% were male, 33.2% had diabetes, and 63.3% were on hemodiafiltration. The median dialysate sodium was 138 (136–140). The median DRT was 140 (45–440) minutes, and 14.9% of patients had DRT >12 hours. Fatigue score was 3.1±2.3, 18% had no fatigue, and 37.7% had a score ≥4. DRT was significantly associated with fatigue score. In multivariable regression analysis, intradialytic reduction in serum sodium and frequency of dialysis were significantly associated with DRT. Factors associated with fatigue included female sex and lower hemoglobin. In patients aged 85 years and above, hemodiafiltration was associated with prolonged DRT.

Conclusions
Modifiable factors associated with prolonged DRT are not exactly similar to those associated with fatigue. Intradialytic reduction in serum sodium and low frequency of dialysis are two independent factors associated with longer DRT, with hemodiafiltration associated with longer recovery in very elderly patients. The hemoglobin level is the modifiable independent factor associated with fatigue. These modifiable factors can be addressed in future interventional trials to improve patients' outcomes.
Gestão do acesso dos serviços de urgência e emergência: revisão integrativa
Authors: Coutinho Samanta Brizolara , Oliveira Michele Mandagara de , Cruz Vânia Dias , Oliveira Íria Ramos , Farias Taís Alves , Silva Lisiane da Cunha Martins da 
Published: August 2024

O presente estudo tem como objetivo descrever as estratégias para gestão do acesso dos serviços de urgência e emergência em nível nacional e internacional. Metodologicamente, trata-se de uma revisão integrativa realizada nas bases de dados Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS), National Library of Medicine/ National Institutes of Health (PubMed) e Scientific Electronic Library Online (SciELO), a partir dos descritores superlotação de emergência; Hierarquização de saúde e utilização de serviço, no mês de junho de 2021, utilizando o filtro de sete anos (2015-2021). Os artigos analisados apontam que encaminhamentos desnecessários, presença de familiares, crescente número de pessoas idosas e horário limitado de outras unidades de saúde ocasionam superlotação nos serviços de urgência e emergência. Apresentam que uma vez identificados os fatores que influenciam a aglomeração nas unidades, modelos de agendamento, classificação de risco e softwares, podem ser desenvolvidos para garantir que a emergência ofereça um serviço mais eficiente. Assim, os aspectos técnico-científicos e administrativos como a dinâmica de funcionamento do serviço nos diferentes turnos, modelo gerencial, modelo assistencial, métodos e equipe de trabalho necessitam ser avaliados a fim de prever a capacidade de atendimento do local, identificar problemas, propor adequações e otimizar a dinâmica assistencial.
Recuperación de áreas degradadas con Paspalum dilatatum cv INIA Chirú y Paspalum notatum cv Pensacola
Authors: Zarza Rodrigo , Cunha Daniel Formoso 
Published: August 2024

La recuperación de áreas agrícolas degradadas se ve afectada por la compactación y baja fertilidad del suelo. Una solución es introducir especies nativas o pioneras. En septiembre de 2013, se sembraron Paspalum dilatatum cv INIA Chirú y Paspalum notatum cv Pensacola en 1.5 y 1.7 ha respectivamente, en la Sociedad Rural de Durazno (33°20’15.95’’ S, 56°31’33.16’’ O). En marzo de 2014, se añadió Lotus pedunculatus cv INIA E-Tanín. Los métodos de siembra fueron, siembra directa para Paspalum y al voleo para Lotus, con densidades de 8, 5 y 5 kg ha-1 respectivamente, y una fertilización de 50 kg ha-1 de 0-46-47-0. Chirú y Pensacola en marzo de 2016 cubrían el 44.7% y 22.1% mientras que la cobertura de E-Tanín era de 2,9 y 3,2%, respectivamente. Las gramíneas mostraron aceptable capacidad de colonización, aunque en manchones por las condiciones del suelo. Los resultados son promisorios para recuperar áreas donde las especies forrajeras clásicas han fracasado, sugiriendo la necesidad de un protocolo agronómico que incluya al pastoreo para acelerar la colonización.
Efficacy evaluation of the compression microvibration method in the treatment of cellulite
Authors: Kardashova Z. Z. , Ratnikova N. O. , Fomicheva A. A. , Vasilenko I. A. 
Published: August 2024

Aim. To study the efficiency of compression microvibration method for correcting structural and functional skin changes in women with gynoid lipodystrophy by analyzing the dynamics of blood microcirculation parameters.Materials and methods. The study involved 27 women aged 40 to 69 years with mild and moderate gynoid lipodystrophy. The Endospheres Therapy course included 12 procedures, 2 times a week for 60 minutes. Before and after the course of therapy the dynamics of microcirculation compartments was evaluated by laser Doppler flowmetry using LAZMA PF, a portable laser blood microcirculation analyzer. Results. The perfusion parameters after the 12th procedure of compression microvibration showed statistically significant increase in basal blood flow parameters and amplitude-frequency spectrum of perfusion oscillations reflecting active and passive mechanisms of microcirculatory channel regulation.Conclusion. The results of positive dynamics of the microcirculatory channel parameters testify to the high efficiency of Endospheres Therapy in the treatment of gynoid lipodystrophy. The method of laser Doppler flowmetry allows objectifying the level of dysfunction of the microcirculatory system and provides personalized control over the adequacy and effectiveness of treatment.
Comorbidity structure in psoriasis patients according to dermatology department data
Authors: Trapeznikova E. A. , Yakubovich A. I. , Gaydarova E. G. 
Published: August 2024

Aim. An analysis of the structure of concomitant pathology in patients with widespread psoriasis vulgaris.Materials and methods. An open, uncontrolled, single-center retrospective study of the case histories of 100 patients with widespread plaque psoriasis who received medical care in a dermatology department of Irkutsk State Medical University clinics was carried out. Concomitant pathology was established on the basis of anamnesis and physical examination, as well as laboratory tests and consultations with a physician and related specialists.Results. Diseases of the gastrointestinal tract accounted for 81%, of which non-alcoholic fatty liver disease was detected in 43%. Endocrinopathies were noted in 72% of patients, a third (30%) had obesity of varying degrees, and 14% had type 2 diabetes mellitus. Pathologies of the circulatory system was diagnosed in 34% of patients, including hypertension in 29%. Psoriatic arthritis was detected in 11% of cases. In patients under 40 years of age, an average of 1–2 comorbid conditions were noted, while the number of concomitant diseases increased to 4–5 by the age of 60. Only 17% of the patients had no comorbidities.Conclusions. In the majority of patients, psoriasis is associated with certain diseases, being a harbinger of their development. This fact should be taken into account when determining personalized treatment tactics.
Concentration of blood adipokines in patients with chronic obstructive pulmonary disease
Authors: Khovaeva Ya. B. , Pankova A. I. , Golovskoy B. V. , Voronova E. I. , Moiseenko N. P. , Sosnin D. Yu. 
Published: August 2024

Aim. To study the serum concentrations of adiponectin and leptin in patients with varying degrees of severity of chronic obstructive pulmonary disease (COPD).Materials and methods. The study included 116 patients divided into two groups: the main group (n = 96) consisting of COPD patients and stratified into four subgroups and a control group (n = 20). The concentration of adiponectin (ng/ml) and leptin was determined by solid-phase enzyme immunoassay (ELISA).Results. Statistically significant differences in serum adiponectin contents were revealed between the control group and COPD patients in stages B, C, and D (p = 0.0004); however, its concentration did not correlate with the body mass index and adipose tissue content. No differences were detected in the concentration of leptin between the groups (p = 0.1288); however, its content correlated with the body mass index (R = –0.710871) and adipose tissue content (R = –0.677900). No noticeable correlation was found between the serum concentrations of adiponectin and leptin (R = –0.098481).Conclusions. The content of individual adipokines demonstrated a different dependence on the anthropometric indicators in COPD patients.
Association of the Arg223Gln polymorphism of leptin receptor gene (LEPR) with clinical, laboratory, and instrumental data in asthma and diabetes type 2 comorbid patients
Authors: Pashkevich A. V. , Serebryakova O. V. 
Published: August 2024

Aim. To study to the frequency of alleles and genotypes of the leptin receptor polymorphism (Arg223Gln) in comorbid patients with asthma and type 2 diabetes, as well as determine the association of leptin receptor genotypes with clinical, laboratory, and instrumental data.Materials and methods. Patients with asthma and type 2 diabetes were divided into three groups for comparative analysis, with 80 people in each group. All groups were subjected to the following procedures: clinical examination, determination of disease control using Asthma Control Test in patients with asthma, laboratory examination (determination of fasting blood glucose, glycated hemoglobin), spirometry, molecular genetic analysis of polymorphism of the leptin receptor (LEPR) Arg223Gln by PCR using kits for determining in the human genome. Nonparametric statistical methods were used to process the data obtained.Results. Patients with a combination of diabetes type 2 and asthma were found to have a higher incidence of G-allele polymorphism of the leptin gene (Arg223Gln) as compared to those with these diseases in isolation. The G-allele of the LEPR polymorphism (Arg223Gln) is associated with a higher incidence of diabetes type 2 in patients with asthma. The association of the G-allele in the LEPR gene was found in patients with a combination of asthma and diabetes type 2 with a failure to achieve the target value of fasting blood glucose, a lower parameter of respiratory function FEV1 and a lower control of asthma.Conclusion. The influence of the leptin receptor polymorphism on the combined course of asthma and type 2 diabetes mellitus is noted. An analysis of the leptin receptor polymorphism (Arg223Gln) is useful when identifying asthma patients at a higher risk of developing diabetes type 2.
Febre reumática e suas repercussões hemodinâmicas
Authors: Pereira Miguel Fontana , Nunes Raissa Martins de Oliveira , Rodrigues Ráislla Ribeiro , Freitas André Alves da Silva , Crisanto Antonio Vinícius Sales de Moraes Souza , Guilhon Luana Amorim , Souza Vanessa Maria Gonçalves de , Silva Renata Barreto da , Guerra Carine Fontes , Silva Nayane Mayse Barbosa 
Published: August 2024

Introdução: A febre reumática é uma doença inflamatória sistêmica que ocorre como uma complicação de uma infecção estreptocócica na garganta, geralmente causada por Streptococcus pyogenes.

Metodologia: Para conduzir um estudo abrangente sobre a febre reumática e suas repercussões hemodinâmicas, a metodologia a ser empregada deve ser rigorosa e bem estruturada. A pesquisa deve começar com uma revisão da literatura disponível nas bases de dados SciELO, Google Acadêmico e PubMed, visando identificar, selecionar e sintetizar as evidências científicas mais relevantes sobre o tema.

Resultado e discussão: As repercussões hemodinâmicas mais notáveis da febre reumática são aquelas que afetam o coração. A cardite reumática pode levar a estenose ou insuficiência das válvulas cardíacas, particularmente as válvulas mitral e aórtica. A estenose mitral é uma complicação comum, onde a válvula mitral se torna estreitada, dificultando o fluxo sanguíneo do átrio esquerdo para o ventrículo esquerdo.

Conclusão: A pesquisa contínua para melhor compreender os mecanismos imunopatológicos subjacentes e o desenvolvimento de novas abordagens terapêuticas são essenciais para melhorar os resultados para os pacientes afetados por esta doença devastadora.
CAPACITAÇÃO PARA OS ACS'S SOBRE A IMPORTÂNCIA DA COLETA ADEQUADA DE DADOS PARA AÇÕES DE PLANEJAMENTO EM SAÚDE
Authors: Marcolino Giulia de Jesus , Oliveira Anna Clara de Jesus , Gonçalves Emanuelle Cristina Soares , Oliveira Gabriela Alves de , Paulino Luanna Simão , Simões Pedro Raydan Brandão 
Published: August 2024

Os Agentes Comunitários de Saúde (ACSs) são profissionais de saúde fundamentais na equipe multidisciplinar, haja vista que representam o elo entre a atenção básica com a população adscrita em seu território. No entanto, inúmeros fatores se sobrepõem para que seus processos de trabalho não sejam realizados de forma adequada, o que contribui para o mau planejamento de ações em saúde. Assim, esse trabalho é um relato de experiência de uma atividade desenvolvida cujo o objetivo foi capacitar os ACSs para a coleta adequada de dados na área de abrangência de uma Unidade Básica de Saúde (UBS) na região metropolitana de Belo Horizonte, disseminando conhecimento técnico e científico da Saúde Coletiva e pontuando quais erros de coleta de dados estavam sendo cometidos. Para que isso ocorresse foi feita uma apresentação presencial em forma de slides para os ACS. A capacitação baseou-se nos dados obtidos na análise de situação de saúde da UBS por meio das fichas de cadastro individual e domiciliar. Para medir o grau de conhecimento adquirido na atividade, um formulário foi respondido antes e depois da apresentação por cada um dos profissionais e comparado ao final da atividade. Observou-se um aumento na taxa de acertos de 36.6% somado aos relatos de desvalorização dentro da equipe de saúde e de situações constrangedoras que dificultam seu trabalho adequado. Logo, o presente trabalho atingiu seu principal objetivo, mas também criou um ambiente favorável à valorização desse profissional tão essencial na atenção básica, uma vez que abriu espaço para a troca de experiências das ACSs.
TERAPIAS ALTERNATIVAS NO CONTROLE DA DOR
Authors: Bersotti Felipe Marrese , Hennemann Francisco José Germano , Salci Gabriel Silva , Godoy Isabella Fonseca Agatti , Carvalho Jéssica Miranda , Lopes Lorena de Almeida , Coelho Phelippe Riccardo Reis 
Published: August 2024

A dor consiste em uma experiência sensitiva e emocional desagradável associada a uma lesão tecidual real ou em potencial. Como uma opção para atenuar, existem as terapias alternativas, reconhecidas pela OMS como uma forma não tradicional e cultural de tratamento. Assim, com o intuito de resumir e comunicar a relação desses dois pontos na literatura científica, esse trabalho foi desenvolvido através de revisão integrativa, seguindo os preceitos do estudo exploratório, baseado em artigos científicos, revistas e periódicos. A busca foi realizada através dos descritores: “Terapias complementares e integrativas”, “Cuidado”, “dor” com o operador booleano AND e OR. Dos artigos selecionados, averiguou-se que ainda a heterogeneidade de resultados, o que sugere a necessidade de novas pesquisas sobre o tema.
La prévision d'ensemble au coeur de la prévision numérique du temps : état des lieux et perspectives
Authors: Plu Matthieu , Raynaud Laure , Brousseau Pierre 
Published: August 2024

En juillet 2022, Météo-France a procédé à une évolution majeure de sa chaîne de prévision basée sur Arpege et Arome : les prévisions d'ensemble et les systèmes déterministes ont dorénavant les mêmes caractéristiques. Cette évolution, commune à la plupart des centres de prévision dans le monde, répond à une exigence fondamentale : les modèles atteignent des résolutions qui rendent nécessaire le recours aux ensembles pour pouvoir mieux anticiper les phénomènes météorologiques, y compris aux échéances inférieures à 48 heures. La littérature depuis les années 1960 jusqu'à nos jours aide à comprendre les limites de prévisibilité rencontrées par Arome, ce qui est illustré sur deux systèmes précipitants de l'automne 2020. Si la prévision numérique du temps est désormais ensembliste, il faut penser le futur de la recherche météorologique et de l'utilisation des prévisions dans ce cadre.
In July 2022, Météo-France implemented a major change to its forecasting suite based on the global system Arpege and the limited-area one Arome: the basic characteristics of ensemble forecasts and those of deterministic systems, such as resolution and lead time, are now the same. This development, which has been generalised in most of the world's major forecasting centres, is a response to a fundamental requirement: models are reaching resolutions that make ensembles necessary in order to better anticipate meteorological phenomena, even on time scales shorter than 48 hours. The theoretical understanding of dynamical systems such as the atmosphere from the 1960s to the present day helps us to understand the limits of predictability encountered by Arome, as illustrated with two precipitation systems that occurred during autumn 2020. If numerical weather prediction is now ensemble-based, we need to think about the future of meteorological research and the use of forecasts in this context.
À la recherche des bonnes équivalences climatiques entre CO2 et méthane
Authors: Perthuis Christian de , Couturier Christian , Szopa Sophie 
Published: August 2024

À quantité égale émise, le méthane exerce un réchauffement plus intense que le CO2, mais sur une période plus courte. Cet article se penche sur les différentes métriques permettant de comparer les impacts climatiques des deux gaz qui présentent toutes des limites. Il recommande de maintenir celle en vigueur dans le cadre de la Convention cadre des Nations unies sur les changements climatiques, tout en améliorant son usage à mesure des progrès de la connaissance scientifique.
For the same quantity emitted, methane causes more intense global warming than CO2, but over a shorter period. This article looks at the different metrics used to compare the climate impacts of the two gases, all of which have limits. It recommends maintaining that in force under the United Nations Framework Convention on Climate Change while improving its usage as scientific knowledge progresses.
Pengaruh Harga dan Citra Merek terhadap Keputusan Pembelian Masker Pokana Saat Pandemi di Makassasar
Authors: Kumala Sari Novita 
Published: August 2024

Pandemi covid-19 telah mengubah perilaku konsumen terutama pada produk kesehatan. Kompetisi di industri tersebut meningkat pesat dan memaksa perusahaan. Untuk menciptakan produk yang sesuai dengan kebutuhan konsumen, salah satunya adalah produk masker medis. Tujuan dari penelitian ini adalah untuk menganalisa pengaruh harga dan citra merek terhadap keputusan pembelian masker pokana di kota Makassar. Metode penelitian yang digunakan adalah analisis regresi linear berganda untuk mengetahui apakah terdapat hubungan antara X tehadap Y. Untuk penentuan sampel peneliti menggunakan rumus Limeshow sehingga diperoleh jumlah sampel. sebanyak 96 responden. Dari hasil pengujian hipotesis yaitu hasil uji t, diperoleh hasil pengujian yang dimana pada hasil uji t menunjukkan bahwa nilai t-hitung < t-tabel pada variabel Harga (X1) yakni 0,337<1.985, sedangkan untuk Variabel Citra merek (X2) diperoleh hasil t-hitung sebesar -0,610, maka -0,610<1.985. Sehingga bisa ditarik kesimpulan bahwa H0 diterima sementara H1 dan H2 ditolak. Nilai tingkat signifikansi yang diperoleh untuk variabel harga sebesar 0,543 atau 0,543>0,05 sementara untuk variabel citra merek didapatkan nilai signifikansi sebesar 0,737 atau 0,737>0,05. Sehingga disimpulkan bahwa harga dan citra merek tidak berpengaruh secara individu terhadap keputusan pembelian masker merek pokana ditengah pandemi di Kota Makassar. Ditinjau dari Hasil uji simultan (Uji F) atau bersama-sama diperoleh hasil nilai signifikansi sebesar 0,828 atau 0,828>0,05. Sementara itu nilai F-hitungnya <F-tabel atau 0,190<3,093. Sehingga dapat disimpulkan bahwa jika secara bersama-sama antara variabel harga dan citra merek tidak berpengaruh terhadap keputusan Pembelian masker Pokana di Kota Makassar.