bluuebunny/crossref_metadata_2025_split huggingface dataset:
Warfarin: Impact on hemostasis after radial catheterization
Authors: Lippe Christina M. , Reineck Elizabeth A. , Kunselman Allen R. , Gilchrist Ian C. 
Published: January 2014

ObjectivesThis study explores bleeding risk of warfarin patients undergoing radial catheterization.BackgroundTraditionally warfarin has been held prior to catheterization due to bleeding risk; however, this practice is being reconsidered with radial access. This study examined if radial patients receiving warfarin have similar hemostasis times to those not taking warfarin.MethodsA convenience sample of patients undergoing radial catheterization was analyzed. Demographics, procedure characteristics, and pharmacologic therapies were reviewed. Hemostasis times, defined as compression band times, were compared. To exclude confounding effects of aspirin and clopidogrel, a separate analysis of band times for each medication was performed. Specifically, analysis of variance models and exact logistic regression models were used to assess means between usage or nonusage of medications (warfarin, aspirin, clopidogrel) while adjusting for other medications.ResultsOf 208 patients, 60 (29%) were taking warfarin. The breakdown of warfarin, aspirin, and clopidogrel use was as follows: 6 (3%) not taking medications; 14 (7%) warfarin alone; 88 (42%) aspirin alone; 2 (1%) clopidogrel alone; 39 (19%) both warfarin and aspirin; 52 (25%) clopidogrel and aspirin; and 7 (3%) warfarin, aspirin, and clopidogrel. No major complications occurred. Mean hemostasis times for warfarin and nonwarfarin patients were not different (118 vs. 116 min; P = 0.25). Likewise, there was no difference for aspirin (117 vs. 114 min; P = 0.70). There was a nonsignificant trend toward clopidogrel prolonging hemostasis (123 vs. 114 min; P = 0.09). Conclusion: There were no apparent differences in adequacy of hemostasis or duration of compression time between patients taking warfarin or not taking warfarin after controlling for antiplatelet therapy. © 2014 Wiley Periodicals, Inc.
Prevalence and anatomical features of acute longitudinal stent deformation: An intravascular ultrasound study
Authors: Inaba Shinji , Weisz Giora , Kobayashi Nobuaki , Saito Shigeo , Dohi Tomotaka , Dong Liang , Wang Lin , Moran Joyce A. , Rabbani LeRoy E. , Parikh Manish A. , Leon Martin B. , Moses Jeffrey W. , Mintz Gary S. , Maehara Akiko 
Published: January 2014

ObjectivesWe report the prevalence and anatomical features of longitudinal stent deformation as detected by intravascular ultrasound (IVUS)BackgroundAngiographic studies have recently reported longitudinal stent deformation as a mechanical complication occurring during percutaneous coronary intervention; however, there are no IVUS studies on this phenomenonMethodsWe retrospectively analyzed 1,489 consecutive stent‐treated lesions in 1,057 patients who underwent IVUS post‐stent implantationResultsSeventeen longitudinal stent deformations in 17 lesions (1.1% per lesion) in 17 patients (1.6% per patient) were identified by IVUS. Of the 17 IVUS‐detected deformations, only three deformations (17.6%) were detectable by angiography. By IVUS, there were three patterns of longitudinal stent deformation: (1) Deformation with intra‐stent wrinkling and overlapping of the proximal and distal stent fragments within a single stent (n = 14), (2) deformation with elongation (n = 2), and (3) deformation with shortening (n = 1). Most of the deformations were located near to the proximal stent edge (88%), consistent with the finding that they were observed in 11 ostial (65%) and eight left main lesions (47%), and 8.3% of 96 left main stented lesions had evidence of deformationConclusionsBy IVUS, longitudinal stent deformation during percutaneous coronary intervention was seen more frequently than in previous studies; however, it is still uncommon (1.1%) except in the left main location. The most frequent pattern was intrastent wrinkling and overlapping of the proximal and distal stent fragments. © 2014 Wiley Periodicals, Inc.
Discomfort assessment in peripheral angiography: Randomized clinical trial of Iodixanol 270 versus Ioversol 320 in diabetics with critical limb ischemia
Authors: Palena Luis Mariano , Sacco Zeno Dal , Brigato Cesare , Sultato Enrico , Barra Domenico , Candeo Alessandro , Manzi Marco 
Published: January 2014

ObjectivesTo assess and compare the intra‐arterial injection–associated discomfort of iodinated contrast media (CM) and the impact on diagnostic efficacy in diabetics with critical limb ischemia (CLI).BackgroundArterial revascularization is a mainstay in patients with CLI. Previous diagnostic angiography is a crucial step that can be affected by CM injection discomfort compromising the revascularization results, and it could vary related to the CM agents.MethodsOne hundred forty‐eight patients received Iodixanol 270 mg iodine pro ml or Ioversol 320 mg iodine pro ml in a prospective, double‐blind, randomized, parallel‐group clinical trial. Injection‐associated discomfort was assessed by Visual Analogic Scale (VAS). Diagnostic efficacy and safety up to 1 week were evaluated.ResultsThe incidence of pain has been around 50% of the all population in study, with lesser incidence of pain (25.7% vs 74.3%; P < 0.0001) and of heat sensation (55.4% vs 85.1%; P < 0.0001), after Iodixanol than after Ioversol injection. Discomfort mean score, according to VAS assessment, was less in the Iodixanol group (8.1 ± 15.3) than in the Ioversol group (36.0 ± 29.7), after first injection (P < 0.001) and for all injections (P < 0.001). A significant difference was also observed in favor of Iodixanol (P < 0.001), respect to mean score of discomfort and heat sensation, assessed by the operators after all the CM injections.ConclusionsIodixanol caused less frequent and severe discomfort, characterized as pain and heat during intra‐arterial administration compared with Ioversol. The pain severity is tightly related to image and diagnosis quality with an impact on the patients for additional injections and larger CM volumes. © 2014 Wiley Periodicals, Inc.
Baseline and 9 months IVUS analysis of the bifurcation‐dedicated biolimus A9‐eluting Axxess stent system: The DIVERGE IVUS substudy
Authors: Buysschaert Ian , Sanidas Elias , Hasegawa Takao , Koo Bon‐Kwon , Honda Yasuhiro , Fitzgerald Peter J. , Verheye Stefan 
Published: January 2014

BackgroundPercutaneous treatment of complex coronary bifurcation lesions remains challenging, even in the drug‐eluting stent era. We sought to evaluate the baseline and 9 months intravascular ultrasound (IVUS) analysis of the Axxess™ stent, a self‐expanding, Biolimus A9™‐eluting, and dedicated bifurcation stent.Methods and ResultsWe enrolled the first 76 patients from selected sites of the 302 patients large DIVERGE trial (a prospective, single‐arm, multicenter trial evaluating the safety and efficacy of the Axxess stent). Both baseline and 9 months IVUS images were collected for serial two‐dimensional (2D) and 3D analysis. A minimal amount and a low percentage of neointimal volume index were seen in the Axxess stent at 9 months (0.4 ± 0.6 mm3/mm and 4.3 ± 5.2%, respectively). Vessel, lumen, and stent volume indices increased significantly (respectively, 17.0 ± 3.6 to 18.9 ± 3.7 mm3/mm, P < 0.0001; 7.3 ± 2.0 to 9.2 ± 2.5 mm3/mm, P < 0.0001; and 7.4 ± 2.0 to 9.6 ± 2.6 mm3/mm, P < 0.0001). This resulted in minimum lumen area (MLA) enlargement (6.1 ± 1.9 to 7.2 ± 2.3 mm2, P < 0.0001), whereas peristent plaque area decreased (8.7 ± 2.5 to 8.5 ± 2.1 mm3/mm, P = 0.016). At 9 months, 16 (26%) incomplete stent apposition (ISA) persisted from baseline, while six resolved (9.7%). Only one (2%) ISA was late acquired. In the additional distal sirolimus‐eluting stents, MLA decreased from 4.3 ± 1.1 to 4.1 ± 1.2 mm2 (P = 0.04) at 9 months for the main branch, and from 3.4 ± 1.2 to 3.2 ± 1.2 mm2 (P = 0.09) for the side branch.ConclusionsThe dedicated bifurcation Axxess stent system demonstrates significant stent volume increase with minimal neointimal formation and a low incidence of late‐acquired ISA at 9 months. © 2014 Wiley Periodicals, Inc.
Hydroformylation in the Realm of Scents
Authors: Gusevskaya Elena V. , Jiménez‐Pinto Jhonny , Börner Armin 
Published: January 2014

AbstractInvited for this month’s front cover is a transatlantic collaboration between academic and industrial researchers in Germany and Brazil. The image shows how the works of Coco Chanel, creator of fragrance Chanel No 5, and Otto Roelen, discoverer of the hydroformylation reaction, overlapped: the perfume had a high proportion of linear aldehydes. See the Review itself at http://dx.doi.org/10.1002/cctc.201300474.
Computational Fluid Dynamics Hydrodynamic Analysis of a Cross‐Orthogonal Fixed‐Valve Tray
Authors: Sun Jinsheng , Luo Xubo , Jiang Shuo , Wang Wenping , Lyu Hao , Wang Pei , Gao Hong 
Published: January 2014

AbstractA computational fluid dynamics model was developed to investigate the hydrodynamic characteristics of a novel orthogonal fixed‐valve tray, which offers a larger effective contact perimeter under the same orifice area than its previously reported counterparts. The liquid‐gas phases were simulated in the Eulerian framework, with the interphase momentum transfer source term based on the experimentally obtained liquid hold‐up correlation. The simulation results were consistent with the experimental data. In addition, the gas hold‐up profile of this new design was compared with its triangular cousin under the conditions of a typical run, showing that the former has a higher froth height, which indicated better interphase contact on the tray.
Experimental Study on a Hot‐Oxygen Burner in a Bench‐Scale Gasifier
Authors: Guo Qinghua , Gong Yan , Yu Guangsuo , Wang Tao , Ma Yi , Yan Zhuoyong 
Published: January 2014

AbstractThe direct‐ignition technology of an entrained‐flow coal‐water slurry gasifier with hot‐oxygen burner (HOB) is presented. Experimental tests were carried out using diesel oil and coal‐water slurry in a bench‐scale entrained‐flow opposed multi‐burner (OMB) gasifier. Using a CCD camera equipped with high‐temperature endoscope, flame images inside the gasifier were recorded and subsequently processed. The results show that the HOB diesel flame is more stable than the normal two‐channel burner flame typically used. Entrained‐flow coal‐water slurry gasifiers can start up using the HOB directly without a higher preheated wall temperature. An HOB can potentially save gasifier preheating time and operation costs and enables a wide range of future applications.
Comparing Different Synthesis Procedures for Carbide‐Derived Carbon‐Based Structured Catalyst Supports
Authors: Knorr Tilman , Schwarz Aaron , Etzold Bastian J. M. 
Published: January 2014

AbstractDifferent approaches were analyzed to combine the tuneable micropore structure of carbide‐derived carbons with a foam‐like secondary porosity. The resulting structured catalyst supports were characterized in detail and applied in the model reaction of ethene hydrogenation. Preparation methods studied were dip‐coating using polytetrafluoroethylene as binder on cellular metal structures, a chemical vapor deposition coating of the metal structures with thin carbide layers and subsequent conversion to carbide‐derived carbon, and the partial or full conversion of carbide foams to carbon/carbide composites. For the binder method, optimal parameters for stable slurry preparation as well as for calcination of the slurry were obtained. It could further be demonstrated that the conversion of carbide foams into carbon/carbide composites leads to an appreciation between decreasing mechanical strength and increasing specific surface area.
In Situ Electrochemical Generation of Mesostructured Cu2S/C Composite for Enhanced Lithium Storage: Mechanism and Material Properties
Authors: Han Fei , Li Wen‐Cui , Li Duo , Lu An‐Hui 
Published: January 2014

AbstractAn effective strategy is explored for the in situ generation of a Cu2S/tubular mesoporous carbon composite by exploiting the charge–discharge processes of a S/C composite on a copper‐foil current collector. By studying the reaction mechanism, we discover that the dissolved polysulfide ions (from the reaction of pristine sulfur) and inserted Li+ are firmly anchored by the copper ions released from the copper foil, which forms insoluble CuxS intermediates in the mesopore channels of the carbon matrix. Moreover, the new electrochemically active CuxS intermediates are gradually converted to the final product, Cu2S, during subsequent cycles. The as‐prepared Cu2S nanoparticles are highly dispersed throughout the tubular mesoporous carbon, and the Cu2S/C composite exhibits a high reversible capacity of 270 mAh g−1 at 0.2 C over 300 cycles, with the negligible capacity loss, when used as a cathode material for a lithium‐ion battery. Furthermore, the composite shows an outstanding rate capability with a reversible capacity of 225 mAh g−1 under a high rate of 10 C. This work provides a convenient platform for the controlled synthesis of metal sulfides for lithium‐storage applications.
Germanium‐Based Electrode Materials for Lithium‐Ion Batteries
Authors: Liu Yang , Zhang Sulin , Zhu Ting 
Published: January 2014

AbstractLithium‐ion batteries (LIBs) with superior energy density, rate capability, and cyclability are critically needed for next‐generation portable electronics and electric vehicles. Germanium (Ge) is a promising candidate material for the high‐capacity anode of LIBs. Although the cost of Ge is the main barrier for its wide application in large‐scale electrochemical energy storage, the electrochemical performance of Ge in LIBs is interesting from both scientific and engineering perspectives. Compared to silicon (Si), Ge has received much less attention, despite the relatively high electronic conductivity and high lithiation–delithiation rate in Ge. In this Concept, we review recent progress in the in situ electrochemical study of the lithiation and delithiation mechanisms in Ge nanowires and nanoparticles. Insights into the nanostructural evolution and mechanical degradation during electrochemical reactions are highlighted. Critical unresolved questions are raised and prospects for the future research of Ge‐based electrodes are discussed.
Influence of Ionic Liquid Selection on the Properties of Poly(Ethylene Glycol) Diacrylate‐Supported Ionogels as Solid Electrolytes
Authors: Visentin Adam F. , Alimena Stephanie , Panzer Matthew J. 
Published: January 2014

AbstractThree room‐temperature ionic liquids (ILs), differing only in anion identity [1‐ethyl‐3‐methylimidazolium tris(pentafluoroethyl)trifluorophosphate (EMI FAP), 1‐ethyl‐3‐methylimidazolium bis(trifluoromethanesulfonyl)imide (EMI TFSI), and 1‐ethyl‐3‐methylimidazolium tetracyanoborate (EMI TCB)], are employed to directly compare the mechanical and electrical responses of cross‐linked, poly(ethylene glycol) diacrylate (PEGDA)‐supported ionogel solid electrolytes. It is observed that the choice of IL influences the minimum amount of polymer required to create a non‐flowing gel, but not the value of the Young’s modulus for a given weight fraction of PEGDA above the gelation point. Furthermore, the relative decrease in ionic conductivity above the gel point is also found to be IL‐independent. These observations suggest that IL contributions to the character of these ionogels can be distinguished from the contributions of the supporting polymer scaffold. In addition, an extremely large ionic conductivity value (13.1 mS cm−1) is achieved at room temperature using EMI TCB at its gelation point (7.2 wt % PEGDA).
Monocyclometalated Gold(III) Monoaryl Complexes—A New Class of Triplet Phosphors with Highly Tunable and Efficient Emission Properties
Authors: Szentkuti Alexander , Bachmann Michael , Garg Jai Anand , Blacque Olivier , Venkatesan Koushik 
Published: January 2014

AbstractHighly tunable and rich phosphorescent emission properties based on the stable monocyclometalated gold(III) monoaryl structural motif are reported. Monochloro complexes of the type cis‐[(N^C)Au(C6H2(CF3)3)(Cl)] N^C=2‐phenylpyridine (ppy)] (1), [N^C=benzo[h]quinoline (bzq)] (2), [N^C=2‐(5‐Methyl‐2‐thienyl)pyridine (5m‐thpy)] (3) were successfully prepared in modest to good yields by reacting an excess of 2, 4, 6‐tris(trifluoromethyl)phenyl lithium (LiFmes) with the corresponding dichloride complexes cis‐[(N^C)AuCl2]. Subsequent replacement of the chloride ligand in 1 with strong ligand field strength such as cyanide and terminal alkynes resulted in complexes of the type cis‐[(ppy)Au(Fmes)(R)] R=CN (4), I (5), CCC6H5 (6) and CCC6H4N(C6H5)‐p (7). Single crystal X‐ray diffraction studies of all the complexes except 7 were performed to further corroborate their chemical identity. Thermogravimetric analysis (TGA) studies of the uncommon cis configured aryl alkyne complex 7 confirmed the high stability of this complex. Detailed photophysical investigations carried out in solution at room temperature, at 77 K (2‐MeTHF) in rigidified media, solid state and 5 wt % PMMA revealed the phosphorescent nature of emission in these complexes. Additionally, their behavior was found to be governed based on both the nature of the cyclometalated ligand and the electronic properties of the ancillary ligands. Highly efficient interligand charge transfer in complex 7 provides access to a wide range of emission colors (solvent‐dependent) from deep blue to red with phosphorescence emission quantum yield of 30 % (441 nm) and 39 % (622 nm) in solution and solid state, respectively, and is the highest reported for any AuIII complexes. DFT and TDDFT calculations carried out further validated the observations and assignments based on the photophysical experimental findings.
Filling Carbon Nanotubes with Prussian Blue Nanoparticles of High Peroxidase‐Like Catalytic Activity for Colorimetric Chemo‐ and Biosensing
Authors: Wang Ting , Fu Yingchun , Chai Liyuan , Chao Long , Bu Lijuan , Meng Yue , Chen Chao , Ma Ming , Xie Qingji , Yao Shouzhuo 
Published: January 2014

AbstractFacile filling of multiwalled carbon nanotubes (MWCNTs) with Prussian blue nanoparticles (PBNPs) of high peroxidase‐like catalytic activity was performed to develop novel colorimetric sensing protocols for assaying H2O2 and glucose. Fine control of PBNP growth was achieved by modulating the concentration ratio of K3[Fe(CN)6] and FeSO4 precursors in an acidic solution containing ultrasonically dispersed MWCNTs, and thus size‐matched PBNPs could be robustly immobilized in the cavities of the MWCNTs (MWCNT‐PBin). Unlike other reported methods involving complicated procedures and rigorous preparation/separation conditions, this mild one‐pot filling method has advantages of easy isolation of final products by centrifugation, good retention of the pristine outer surface of the MWCNT shell, and satisfactory filling yield of (24±2) %. In particular, encapsulation of PBNPs of poor dispersibility and limited functionality in dispersible and multifunctional MWCNT shells creates new and valuable opportunities for quasihomogeneous‐phase applications of PB in liquid solutions. The MWCNT‐PBin nanocomposites were exploited as a peroxidase mimic for the colorimetric assay of H2O2 in solution by using 3,3′,5,5′‐tetramethylbenzidine (TMB) as reporter, and they gave a linear absorbance response from 1 μM to 1.5 mM with a limit of detection (LOD) of 100 nM. Moreover, glucose oxidase (GOx) was anchored on the outer surface of MWCNT‐PBin to form GOx/MWCNT‐PBin bionanocomposites. The cooperation of outer‐surface biocatalysis with peroxidase‐like catalysis of interior PB resulted in a novel cooperative colorimetric biosensing mode for glucose assay. The use of GOx/MWCNT‐PBin for colorimetric biosensing of glucose gave a linear absorbance response from 1 μM to 1.0 mM and an LOD of 200 nM. The presented protocols may be extended to other multifunctional nanocomposite systems for broad applications in catalysis and biotechnology.
TiO2 Nanotube Arrays Modified with Cr‐Doped SrTiO3 Nanocubes for Highly Efficient Hydrogen Evolution under Visible Light
Authors: Jiao Zhengbo , Zhang Yan , Chen Tao , Dong Qingsong , Lu Gongxuan , Bi Yingpu 
Published: January 2014

AbstractIn recent decades, solar‐driven hydrogen production over semiconductors has attracted tremendous interest owing to the global energy and environmental crisis. Among various semiconductor materials, TiO2 exhibits outstanding photocatalytic properties and has been extensively applied in diverse photocatalytic and photoelectric systems. However, two major drawbacks limit practical applications, namely, high charge‐recombination rate and poor visible‐light utilization. In this work, heterostructured TiO2 nanotube arrays grafted with Cr‐doped SrTiO3 nanocubes were fabricated by simply controlling the kinetics of hydrothermal reactions. It was found that coupling TiO2 nanotube arrays with regular SrTiO3 nanocubes can significantly improve the charge separation. Meanwhile, doping Cr cations into SrTiO3 nanocubes proved to be an effective and feasible approach to enhance remarkably the visible‐light response, which was also confirmed by theoretical calculations. As a result, the rate of photoelectrochemical hydrogen evolution of these novel heteronanostructures is an order of magnitude larger than those of TiO2 nanotube arrays and other previously reported SrTiO3/TiO2 nanocomposites under visible‐light irradiation. Furthermore, the as‐prepared Cr‐doped SrTiO3/TiO2 heterostructures exhibit excellent durability and stability, which are favorable for practical hydrogen production and photoelectric nanodevices.
One‐Pot Synthesis of Fused Pyrroles through a Key Gold‐Catalysis‐Triggered Cascade
Authors: Zheng Zhitong , Tu Huangfei , Zhang Liming 
Published: January 2014

AbstractA two‐step, one‐pot synthesis of fused pyrroles is realized by firstly condensing an N‐alkynylhydroxammonium salt with a readily enolizable ketone under mild basic conditions and then subjecting the reaction mixture to a gold catalyst, which triggers a cascade reaction involving a facile initial [3.3]‐sigmatropic rearrangement of the gold‐catalysis product, that is, an N,O‐dialkenylhydroxamine. The reaction provides a facile access to polycyclic pyrroles in moderate to good yields.
Simultaneous LC/ESI‐MS Separation Method for the Enantioseparation of Some New Anticonvulsant Drugs
Authors: Walczak Maria , Pekala Elzbieta , Waszkielewicz Anna M. , Marona Henryk 
Published: January 2014

ABSTRACTA sensitive and specific method for the simultaneous determination of the enantiomeric purity of 2,6‐dimethylphenoxyacetyl derivatives as trans or cis racemic and enantiomeric forms with 2‐ or 4‐aminocyclohexanol moiety (1, 2, 3, 6) and their amine analogs (8, 9) was developed. The compounds studied are known for their anticonvulsant activity and the most interesting pharmacological results were those for (±)‐trans‐2‐(2,6‐dimethylphenoxy)‐N‐(2‐hydroxycyclohexyl)acetamide (1) as well as (±)‐trans‐2‐[(2,6‐dimethylphenoxy)ethyl]aminocyclohexanol (8). The analytical method for determining the enantiomeric purity of the compounds studied is based on direct separation of the analytes using a chiral stationary phase (Chiralpak AS column). The mass spectrometric analysis was done on a coupled liquid chromatograph–mass spectrometer system with an electrospray ionization source (LC/ESI‐MS). For the compounds 1, 8, and 9, the method allows an excellent separation of enantiomers, with a resolution higher than 3.2, and a tailing factor of less than 1.67 with a final enantiomer purity better than 97.5%. Chirality 26:144–149, 2014. © 2014 Wiley Periodicals, Inc.
Influence of Process Parameters on the Nonaqueous Synthesis of TiO2 Nanoparticles
Authors: Zimmermann Mandy , Garnweitner Georg 
Published: January 2014

AbstractDie nichtwässrige Synthese von TiO2‐Nanopartikeln in Benzylalkohol in einem 1,5‐L‐Edelstahlreaktor wurde als Modellsystem hinsichtlich des Einflusses verschiedener Prozessparameter eingehend untersucht. Dabei konnte der Reaktionsverlauf mit der Entwicklung des Systemdruckes korreliert werden, da parallel zur Partikelbildung ein spontaner Druckanstieg durch die Freisetzung von Wasser erfolgt.