bluuebunny/crossref_metadata_2025_split huggingface dataset:
A systems approach to developing user requirements for increased pulmonary rehabilitation uptake by COPD patients
Authors: Early Frances , Ward James , Komashie Alexander , Kipouros Timoleon , Clarkson John , Fuld Jonathan 
Published: July 2024

AbstractChronic Obstructive Pulmonary Disease is a progressive lung disease associated with anxiety, depression, and reduced health-related quality of life. Pulmonary rehabilitation (PR) is a cost-effective and transformative treatment, but 31% of referred patients do not take up their PR appointment. The study aimed to develop user requirements for an intervention to increase PR uptake. A systems approach, the Engineering Better Care framework, was used to develop a system map of the PR pathway, translate evidence-based user needs into user requirements, and validate the user requirements in a stakeholder workshop. Eight user requirements addressed patient and health care practitioner needs to understand what PR entails, understand the benefits of PR and have positive conversations about PR to address patient concerns. The solution-independent user requirements can be applied to the development of any intervention sharing similar goals. The study demonstrates potential in taking a systems approach to more challenges within respiratory medicine.
A cortical surface template for human neuroscience
Authors: Feilong Ma , Jiahui Guo , Gobbini Maria Ida , Haxby James V. 
Published: July 2024

AbstractNeuroimaging data analysis relies on normalization to standard anatomical templates to resolve macroanatomical differences across brains. Existing human cortical surface templates sample locations unevenly because of distortions introduced by inflation of the folded cortex into a standard shape. Here we present the onavg template, which affords uniform sampling of the cortex. We created the onavg template based on openly available high-quality structural scans of 1,031 brains—25 times more than existing cortical templates. We optimized the vertex locations based on cortical anatomy, achieving an even distribution. We observed consistently higher multivariate pattern classification accuracies and representational geometry inter-participant correlations based on onavg than on other templates, and onavg only needs three-quarters as much data to achieve the same performance compared with other templates. The optimized sampling also reduces CPU time across algorithms by 1.3–22.4% due to less variation in the number of vertices in each searchlight.
Effects of gravel on the water infiltration process and hydraulic parameters of stony soil in the eastern foothills of Helan Mountain, China
Authors: Ma Yan , Wang Youqi , Zhang Yuhan , Zhang Ruiyuan , Yuan Cheng , Ma Chengfeng , Bai Yiru 
Published: July 2024

AbstractThe investigation into the impact of gravel on water infiltration process and hydraulic parameters in stony soil could offer a theoretical basis to enhance water availability in rocky mountain area. A one-dimensional vertical infiltration experiment was used in this study. Six groups of gravel content of 0% (CK), 10% (W1), 20% (W2), 30% (W3), 40% (W4) and 50% (W5) were established to explore the changes in the wetting front, cumulative infiltration volume and infiltration rate. Then the accuracy of four infiltration models in simulating soil water infiltration processes was evaluated. Finally, Hydrus-1D was used to perform numerical inversion of the soil water content after infiltration. The findings revealed that: (1) When the infiltration time reached 300 min, the wetting front of the W1, W2, W3, W4 and W5 treatments was 11.00%, 17.00%, 32.25%, 38.75% and 54.50% lower than CK, the cumulative infiltration volume was 29.80%, 38.97%, 45.62%, 54.74% and 73.17% lower than CK, and the stable infiltration rate was 50.98%, 52.94%, 66.67%, 68.63% and 86.27% lower than CK. (2) The soil–water infiltration processes were accurately described by the Horton model, the coefficient of determination (R2) > 0.935. (3) The simulation results of Hydrus-1D showed that with the increase of gravel content, the values of the retention water content (θr), saturated water content (θs), shape coefficient (n) and saturated hydraulic conductivity (Ks) were decreased, the values of the reciprocal of air-entry (α) were increased. The value of R2 was more than 0.894, the root mean square error (RMSE) and mean absolute error (MAE) were less than 2%, which demonstrated that the Hydrus-1D model exhibited superior capability in simulating the changes of water content in stony soil in rocky mountain area. The findings of this study demonstrated that gravel could decrease the water infiltration process and affect the water availability. It could provide data support for the water movement process of stony soil and rational utilization of limited water resources in mountainous area.
Multi-angle property analysis and stress–strain curve prediction of cementitious sand gravel based on triaxial test
Authors: Tian Qingqing , Guo Lei , Zhang Yiqing , Gao Hang , Li Zexuan 
Published: July 2024

AbstractIn order to further promote the application of cementitious sand gravel (CSG), the mechanical properties and variation rules of CSG material under triaxial test were studied. Considering the influence of fly ash content, water-binder ratio, sand rate and lateral confining pressure, 81 cylinder specimens were designed and made for conventional triaxial test, and the influence laws of stress–strain curve, failure pattern, elastic modulus, energy dissipation and damage evolution of specimens were analyzed. The results showed that the peak of stress–strain curve increased with the increase of confining pressure, and the peak stress, peak strain and energy dissipation all increased significantly, but the damage variable D decreased with the increase of confining pressure. Under triaxial compression, the specimen was basically sheared failure from the bonding surface, and the aggregate generally did not break. Sand rate had a significant effect on the peak stress of CSG, and decreased with the increase of sand rate. Under the conditions of the same cement content, fly ash content and confining pressure, the optimal water-binder ratio 1.2 existed when the sand rate was 0.2 and 0.3. After analyzing and processing the stress–strain curve of triaxial test, a Cuckoo Search-eXtreme Gradient Boosting (CS-XGBoost) curve prediction model was established, and the model was evaluated by evaluation indexes R2, RMSE and MAE. The average R2 of the XGBoost model based on initial parameters under 18 different output features was 0.8573, and the average R2 of the CS-XGBoost model was 0.9516, an increase of 10.10%. Moreover, the prediction curve was highly consistent with the test curve, indicating that the CS algorithm had significant advantages. The CS-XGBoost model could accurately predict the triaxial stress–strain curve of CSG.
Analysis of food system drivers of deforestation highlights foreign direct investments and urbanization as threats to tropical forests
Authors: Sylvester Janelle M. , Gutiérrez-Zapata Diana María , Pérez-Marulanda Lisset , Vanegas-Cubillos Martha , Bruun Thilde Bech , Mertz Ole , Castro-Nunez Augusto 
Published: July 2024

AbstractApproximately 90% of global forest cover changes between 2000 and 2018 were attributable to agricultural expansion, making food production the leading direct driver of deforestation. While previous studies have focused on the interaction between human and environmental systems, limited research has explored deforestation from a food system perspective. This study analyzes the drivers of deforestation in 40 tropical and subtropical countries (2004–2021) through the lenses of consumption/demand, production/supply and trade/distribution using Extreme Gradient Boosting (XGBoost) models. Our models explained a substantial portion of deforestation variability globally (R2 = 0.74) and in Asia (R2 = 0.81) and Latin America (R2 = 0.73). The results indicate that trade- and demand-side dynamics, specifically foreign direct investments and urban population growth, play key roles in influencing deforestation trends at these scales, suggesting that food system-based interventions could be effective in mitigating deforestation. Conversely, the model for Africa showed weaker explanatory power (R2 = 0.30), suggesting that factors beyond the food system may play a larger role in this region. Our findings highlight the importance of targeting trade- and demand-side dynamics to reduce deforestation and how interventions within the food system could synergistically contribute to achieving sustainable development goals, such as climate action, life on land and zero hunger.
Modulation of the attentional response to baby schema by testosterone in pedohebephilic men and its relation to the nurturing system
Authors: Zannoni Ronja , Keil Julian , Ponseti Jorge , Stirn Aglaja V. , Holtfrerich Sarah K. C. , Diekhof Esther K. 
Published: July 2024

AbstractPrevious fMRI research found increased brain responses in men with pedophilic interest to non-sexual pictures of child and animal faces. This raised the question of whether an aberrant nurturing system could be linked to pedophilia. To further explore this hypothesis, 20 pedohebephilic and 23 teleiophilic men performed a target detection task with adult versus infant human and animal faces, which measured selective attention towards the baby schema by comparing reaction times to infant versus adult targets that were presented amongst distractors of the other category. Since the response to baby schema can be influenced by steroid hormones, saliva samples were additionally collected to determine endogenous testosterone, progesterone, estradiol and cortisol. Contrary to expectations, all men did not react faster to infant than adult faces. Yet, pedohebephilic men were more distracted by infant’s faces than teleiophilic men. Pedohebephilic men with higher testosterone were faster in orienting attention to infant targets in the context of adult distractors. This association was not observed in teleiophilic men. Our results support the idea of an overactive nurturing system in pedophilia, which may be influenced by the endogenous testosterone level.
The association between blood urea nitrogen to albumin ratio and the 28 day mortality in tuberculosis patients complicated by sepsis
Authors: Cui Kunping , Feng Shuang , Mao Yi , Luo Haixia , Yang Jiao , Xu Ruyi , Bai Lang 
Published: July 2024

AbstractThe relationship between blood urea nitrogen to albumin ratio (BAR) and the prognosis of patients with tuberculosis (TB) complicated by sepsis remains unclear. This study aimed to explore the association between BAR and overall patient prognosis. This was a retrospective cohort study of patients with TB complicated by sepsis who were admitted to the intensive care unit (ICU) of the Public Health Clinical Center of Chengdu between January 2019 and February 2023. The relationship between BAR values and prognosis in these patients was investigated using multivariate Cox regression, stratified analysis with interaction, restricted cubic spline (RCS), and threshold effect analysis. Sensitivity analyses were conducted to assess the robustness of the results. Our study included 537 TB patients complicated by sepsis admitted in the ICU, with a median age of 63.0 (48.0, 72.0) years; 76.7% of whom were men. The multivariate-restricted cubic spline analysis showed a non-linear association between BAR and patient prognosis. In the threshold analysis, we found that TB patients complicated by sepsis and a BAR < 7.916 mg/g had an adjusted hazard ratio (HR) for prognosis of 1.163 (95% CI 1.038–1.303; P = 0.009). However, when the BAR was ≥ 7.916 mg/g, there was no significant increase in the risk of death. The results of the sensitivity analysis were stable.
Sustainable removal of tetracycline and paracetamol from water using magnetic activated carbon derived from pine fruit waste
Authors: Hashemzadeh Farzad , Ariannezhad Maryam , Derakhshandeh Seyed Hamed 
Published: July 2024

AbstractThis work presents highly porous magnetic activated carbon nanoparticles (MPFRC-A) derived from pine fruit residue. The MPFRC-A were produced through a three-step process: physical activation (carbonization temperature: 110–550 °C), chemical activation (H2SO4 (0.1 N, 96%)), and co-precipitation. These nanoparticles were then used to remove tetracycline (TC) and paracetamol (PC) from water. Functionalization with Fe3O4 nanoparticles on the surface of the pine fruit residue-derived activated carbon (PFRC-A) resulted in high saturation magnetization, allowing for separation from aqueous solution using an external magnet. The MPFRC-A adsorbent was characterized by Brunauer–Emmett–Teller (BET) analysis, Fourier-transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), X-ray diffraction (XRD), and Energy-dispersive X-ray spectroscopy (EDX) analyses, In the experimental section, the effects of various factors on the adsorption process were investigated, including pH, contact time, initial pollutant concentrations, adsorbent dosage, and temperature. Based on these investigations, adsorption isotherm models and kinetics were studied and determined. The results showed that MPFRC-A exhibited a large specific surface area (182.5 m2/g) and a high total pore volume (0.33 cm3/g). The maximum adsorption capacity was achieved at pH 6 and 5 for PC and TC drugs with an adsorbent dose of 400 mg and an initial concentration of 20 mg/L at 25 °C. The study revealed that the experimental data were well-fitted by the Langmuir isotherm model (R2 > 0.98), with maximum uptake capacities of 43.75 mg/g for TC and 41.7 mg/g for PC. Outcomes of the adsorption thermodynamics shows non-spontaneity of the reaction and the adsorption process by all adsorbents was endothermic.
Heat transfer innovation of engine oil conveying SWCNTs-MWCNTs-TiO2 nanoparticles embedded in a porous stretching cylinder
Authors: Ramasekhar Gunisetty , Divya A. , Jakeer Shaik , Reddy S. R. R. , Algehyne Ebrahem A. , Jawad Muhammad , Akgül Ali , Hassani Murad Khan 
Published: July 2024

AbstractThe influence of boundary layer flow of heat transfer analysis on hybrid nanofluid across an extended cylinder is the main focus of the current research. In addition, the impressions of magnetohydrodynamic, porous medium and thermal radiation are part of this investigation. Arrogate similarity variables are employed to transform the governing modelled partial differential equations into a couple of highly nonlinear ordinary differential equations. A numerical approach based on the BVP Midrich scheme in MAPLE solver is employed for solution of the set of resulting ordinary differential equations and obtained results are compared with existing literature. The effect of active important physical parameters like Magnetic Field, Porosity parameter, Eckert number, Prandtl number and thermal radiation parameters on dimensionless velocity and energy fields are employed via graphs and tables. The velocity profile decreased by about 65% when the magnetic field parameter values increases from 0.5 to 1.5. On the other hand increased by 70% on energy profile. The energy profile enhanced by about 62% when the Radiation parameter values increases from 1.0 < Rd < 3.0. The current model may be applicable in real life practical implications of employing Engine oil-SWCNTs-MWCNTs-TiO2 nanofluids on cylinders encompass enhanced heat transfer efficiency, and extended component lifespan, energy savings, and environmental benefits. This kind of theoretical analysis may be used in daily life applications, such as engineering and automobile industries.
A 12-month randomized controlled trial to assess the efficacy of revitalization of retreated mature incisors with periapical radiolucency in adolescents
Authors: Elheeny Ahmad Abdel Hamid , Hussien Osama Seif-Elnasr , Abdelmotelb Mahmoud Ahmed , ElMakawi Yassmin Mohamed , Wahba Norhan Khaled Omar 
Published: July 2024

AbstractThe use of regenrative endodontics is restoring the health status of the root canals of retreated mature teeth is a novel approach. Therefore, the current trial aimed to compare the effectiveness of regenerative endodontic procedures (REPs) to non-surgical root canal retreatment (NS-RCR) in reducing periapical radiolucency over one year for the retreatment of mature incisors with periapical periodontitis. The secondary purpose was to assess clinical success and regain pulp sensibility. A parallel randomized controlled trial, 66 mature incisors with periapical radiolucencies were randomly divided into two equal groups and retreated with either REPs or NS-RCR. At baseline and after 6 and 12 months, teeth were assessed clinically and radiographically using a periapical index (PAI). The Mann–Whitney test was used to analyze nonparametric PAI scores. The Electric pulp test readings were analyzed using the repeated measure analysis of variance (ANOVA). Over the follow-up intervals, there was no significant intergroup difference in the PAI medians, the majority of the teeth displayed a reduction in periapical radiolucency. At the end of the follow-up period, the clinical successes for the REP and NS-RCR groups were 93.9% and 97%, respectively (p = 0.555). Positive pulp sensibility was recorded in 54.54% of cases in the REPs after 12 months. Both approaches showed a comparable diminishing of periapical radiolucencies and equivalent clinical results. A conventional, non-surgical endodontic retreatment may not always be necessary.
Sedimentological and petrophysical characterization of the Bokabil Formation in the Surma Basin for CO2 storage capacity estimation
Authors: Hossain Shakhawat , Rahman Naymur , Shekhar Himadri 
Published: July 2024

AbstractLarge-scale geological sequestration of CO2is one of the most effective strategies to limit global warming to below 2 °C, as recommended by the Intergovernmental Panel on Climate Change (IPCC). Therefore, identifying and characterizing high-quality storage units is crucial. The Surma Basin, with its four-way dip closed structures, high-quality reservoirs, and thick regional cap rocks, is an ideal location for CO2storage. This study focuses on the Bokabil Formation, the most prominent reservoir unit in the Surma Basin. Detailed petrographic, petrophysical, XRD, and SEM analyses, along with mapping, have been conducted to evaluate the properties of the reservoir and cap rock within this formation. The Upper Bokabil Sandstone in the Surma Basin ranges from 270 to 350 m in thickness and consists of fine- to medium-grained subarkosic sandstones composed of 70–85% quartz and 5–12% feldspar, with good pore connectivity. Petrophysical analysis of data from four gas fields indicates that this unit has a total porosity of 21–27.4% and a low shale volume of 15–27%. Cross plots and outcrop observations suggest that most of the shales are laminated within the reservoir. The regional cap rock, known as the Upper Marine Shale (UMS), ranges in thickness from 40 to 190 m and contains 10–40 nm nano-type pores. A higher proportion of ductile materials with a significant percentage of quartz in the UMS indicates higher capillary entry pressures, enhancing its capacity to hold CO2. Using the CSLF method with a 6% cut-off of the available pore volume, it is estimated that 103 Mt, 110 Mt, 205 Mt, and 164 Mt of CO2can be effectively stored in the Sylhet, Kailashtila, Habiganj, and Fenchuganj structures, respectively. Due to the shallow depth of the storage unit and the thick cap rock, the southern Surma Basin is the optimal location for CO2injection.
Lung quantitative ultrasound to stage and monitor interstitial lung diseases
Authors: Dashti Azadeh , Roshankhah Roshan , Lye Theresa , Blackwell John , Montgomery Stephanie , Egan Thomas , Mamou Jonathan , Muller Marie 
Published: July 2024

AbstractChronic interstitial lung diseases (ILDs) require frequent point-of-care monitoring. X-ray-based methods lack resolution and are ionizing. Chest computerized tomographic (CT) scans are expensive and provide more radiation. Conventional ultrasound can detect severe lung damage via vertical artifacts (B-lines). However, this information is not quantitative, and the appearance of B-lines is operator- and system-dependent. Here we demonstrate novel ultrasound-based biomarkers to assess severity of ILDs. Lung alveoli scatter ultrasound waves, leading to a complex acoustic signature, which is affected by changes in alveolar density due to ILDs. We exploit ultrasound scattering in the lung and combine quantitative ultrasound (QUS) parameters, to develop ultrasound-based biomarkers that significantly correlate (p = 1e−4 for edema and p = 3e−7 for fibrosis) to the severity of pulmonary fibrosis and edema in rodent lungs. These innovative QUS biomarkers will be very significant for monitoring severity of chronic ILDs and response to treatment, especially in this new era of miniaturized and highly portable ultrasound devices.
Comparison of decarboxylation rates of acidic cannabinoids between secretory cavity contents and air-dried inflorescence extracts in Cannabis sativa cv. ‘Cherry Wine’
Authors: Kim Eun-Soo , Park Sang-Hyuck , Kinney Chad A. , Olejar Kenneth J. , Corredor-Perilla Ingrid Carolina 
Published: July 2024

AbstractStudies with secretory cavity contents and air-dried inflorescence extracts of the CBD-rich hemp strain, Cannabis sativa cv. ‘Cherry Wine’, were conducted to compare the decarboxylation rates of acidic cannabinoids between two groups. The secretory cavity contents acquired from the capitate-stalked glandular trichomes by glass microcapillaries, and inflorescence samples air-dried for 15 days of storage in darkness at room temperature were analysed by high-pressure liquid chromatography. The ratio of acidic cannabinoids to the total cannabinoids was ranging from 0.5% to 2.4% lower in the air-dried inflorescence samples compared to the secretory cavity samples as follows. In the secretory cavity content, the percentage of acidic cannabinoids to the total cannabinoids was measured as 86.4% cannabidiolic acid (CBDA), 6.5% tetrahydrocannabinolic acid (THCA), 4.3% cannabichromenic acid (CBCA), 1.4% cannabigerolic acid (CBGA), and 0.6% cannabidivarinic acid (CBDVA), respectively. In the air-dried inflorescence, however, the acidic cannabinoids were detected with 84% CBDA, 4.8% THCA, 3.3% CBCA, 0.8% CBGA, and 0.3% Δ9-tetrahydrocannabivarinic acid (Δ9-THCVA), respectively. The ratio of cannabidiol (CBD) to cannabidiolic acid (CBDA) was close to 1:99 (w/w) in secretory cavity contents, however, it was roughly 1:20 (w/w) in the air-dried inflorescence. In addition, Δ9-tetrahydrocannabivarin (Δ9-THCV) and Δ9-tetrahydrocannabivarinic acid (Δ9-THCVA) were only detected in the air-dried inflorescence sample, and the ratio of Δ9-THCV to Δ9-THCVA was about 1:20 (w/w). Besides, cannabidivarinic acid (CBDVA) was only observed in the secretory cavity content.