bluuebunny/crossref_metadata_2025_split huggingface dataset:
Attentional Bias to Angry Faces: Contrasting Responses in Typically Developing Children and Children with Autism Spectrum Disorder
Authors: Kim S.-Y. , Choi Y. 
Published: August 2024

IntroductionHuman faces generally attract immediate attention. However, it has been found that children with autism spectrum disorder (ASD) tend to allocate relatively less attention to faces. Previous research showed that typically developing children (TD) exhibited an attentional bias to angry faces, regardless of their anxiety levels, but it’s unclear if this applies to children with ASD. Therefore, the present study aims to investigate attentional bias induced by angry and/or happy faces in children with ASD.ObjectivesWe explored attentional bias toward angry faces in both TD children and children with ASD. We hypothesize that while TD children will show attentional capture effects in response to angry faces, children with ASD will not exhibit such attentional bias to facial stimuli, irrespective of their emotional content.MethodsBy now, five ASD participants (all male) and 34 TD participants (17 male), aged 6-12, have completed a continuous performance task. In this task, irrelevant distractors (angry or happy faces) appeared and disappeared abruptly, while the orientation of the target changed every 1,250 ms. Participants were asked to respond as quickly and accurately as possible to the orientaiton of the target. We designated the time when the distractor first appeared as T1, and subsequent time intervals at 1,250 ms increments were labeled as T2, T3, and T4. The time intervals when no distractor was present were labeled as TB (baseline). If the reaction time (RT) at T1 was significantly slower compared to TB, it indicated attentional bias by the distractor.ResultsFor the RT data, separate repeated measures ANOVAs with 2 (emotion) * 5 (time) factors were conducted for each group. The results revealed a significant main effect of time (F(4, 132) = 17.59, p < .01) and a significant interaction between emotion and time (F(3.27, 107.74) = 4.92, p < .01) only in TD. Post hoc t-tests indicated that TD children exhibited significantly slower RT at T1 compared to TB, but this difference was observed only for angry faces (t(33) = 4.84, p < .01). In contrast, no significant effect was found in children with ASD. In other words, TD demonstrated attentional bias only when exposed to angry faces, while ASD children did not exhibit attentional bias to either emotion.ConclusionsThis study aimed to investigate attentional bias to angry faces in both TD and ASD children. The results indicate that TD children exhibited an attentional bias when exposed to angry faces, whereas ASD children did not display such bias. These findings are consistent with previous research suggesting that TD children tend to show attentional bias towards angry faces, regardless of their anxiety levels. Furthermore, the absence of attentional bias to angry faces in ASD suggests that their characteristic of reduced attention to faces may contribute to the lack of attentional bias towards angry faces.Disclosure of InterestNone Declared
The effect of Self-Regulation Based Cognitive Psychoeducation Program on emotion regulation and self-efficacy in children diagnosed with attention deficit hyperactivity disorder
Authors: Sökmen Z. , Karaca S. 
Published: August 2024

IntroductionAttention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder with early onset (Christiansen, H., et al. CPR 2019, 1–11), which is characterized by several symptoms, including lack of attention, hyperactivity, and impulsivity that are incompatible with age and developmental level (Caye, A., et al. 2020 JAACAP, 990–997)ObjectivesThis study aimed to determine the effect of Self-Regulation Based Cognitive Psychoeducation Program on emotion regulation and self-efficacy in children diagnosed with attention deficit hyperactivity disorder (ADHD) and receiving medication.MethodsThe sample of this study with control group and pre-test, post-test and follow-up randomized experimental design consisted of children followed in the child and adolescent mental health outpatient clinic of a state hospital. The data were evaluated by parametric and non-parametric analyses.ResultsA statistically significant increase was determined in the internal functional emotion regulation mean scores of children, who participated in the Self-Regulation Based Cognitive Psychoeducation Program, measured before, immediately after, and 6 months after the intervention (p < 0.05). A statistically significant increase was also found in their external functional emotion regulation mean scores measured before and 6 months after the intervention (p < 0.05). In addition, a statistically significant difference was found between their internal dysfunctional and external dysfunctional emotion regulation mean scores measured before and 6 months after the intervention; however the mean scores of those in the control group 6 months after the intervention were higher than those in the intervention group (p < 0.05). Furthermore, there was a statistically significant increase in their self-efficacy mean scores measured before and 6 months after the intervention (p < 0.05).ConclusionsThe Self-Regulation Based Cognitive Psychoeducation Program was found be effective in increasing the levels of emotion regulation and self-efficacy in children with ADHD.Disclosure of InterestNone Declared
Clinical Outcomes and Histologic Findings of Patients With Hepatocellular Carcinoma With Durable Partial Response or Durable Stable Disease After Receiving Atezolizumab Plus Bevacizumab
Authors: Shen Ying-Chun , Liu Tsung-Hao , Nicholas Alan , Soyama Akihiko , Yuan Chang-Tsu , Chen Tse-Ching , Eguchi Susumu , Yoshizumi Tomoharu , Itoh Shinji , Nakamura Noriaki , Kosaka Hisashi , Kaibori Masaki , Ishii Takamichi , Hatano Etsuro , Ogawa Chikara , Naganuma Atsushi , Kakizaki Satoru , Cheng Chih-Hsien , Lin Po-Ting , Su Yung-Yeh , Chuang Chien-Huai , Lu Li-Chun , Wu Chi-Jung , Wang Hung-Wei , Rau Kun-Ming , Hsu Chih-Hung , Lin Shi-Ming , Huang Yi-Hsiang , Hernandez Sairy , Finn Richard S. , Kudo Masatoshi , Cheng Ann-Lii 
Published: August 2024

PURPOSE
Durable partial response (PR) and durable stable disease (SD) are often seen in patients with hepatocellular carcinoma (HCC) receiving atezolizumab plus bevacizumab (atezo-bev). This study investigates the outcome of these patients and the histopathology of the residual tumors.

PATIENTS AND METHODS
The IMbrave150 study's atezo-bev group was analyzed. PR or SD per RECIST v1.1 lasting more than 6 months was defined as durable. For histologic analysis, a comparable real-world group of patients from Japan and Taiwan who had undergone resection of residual tumors after atezo-bev was investigated.

RESULTS

In the IMbrave150 study, 56 (77.8%) of the 72 PRs and 41 (28.5%) of the 144 SDs were considered durable. The median overall survival was not estimable for patients with durable PR and 23.7 months for those with durable SD. The median progression-free survival was 23.2 months for patients with durable PR and 13.2 months for those with durable SD. In the real-world setting, a total of 38 tumors were resected from 32 patients (23 PRs and nine SDs) receiving atezo-bev. Pathologic complete responses (PCRs) were more frequent in PR tumors than SD tumors (57.7%
v
16.7%,
P
= .034). PCR rate correlated with time from atezo-bev initiation to resection and was 55.6% (5 of 9) for PR tumors resected beyond 8 months after starting atezo-bev, a time practically corresponding to the durable PR definition used for IMbrave150. We found no reliable radiologic features to predict PCR of the residual tumors.

CONCLUSION
Durable PR patients from the atezo-bev group showed a favorable outcome, which may be partly explained by the high rate of PCR lesions. Early recognition of PCR lesions may help subsequent treatment decision.
Exploiting automatic differentiation for quantum optimal control of driven dissipative two-level systems
Authors: Jirari H. , Rabitz H. 
Published: August 2024

Abstract
In principle one can use Pontryagin's minimum principle to treat an optimal control problem and derive the gradient for the cost functional. However, for the driven spin-boson model studied here, the response of the system to the variation of the control is determined by the master equation and the equation of motion for the propagator of the coherent system dynamics. As a result, the application of Pontryagin's minimum principle is less straightforward. An alternative to this approach is the technique of automatic differentiation which in principle amounts to doing calculus on the fully discretized form of the optimal control problem. Automatic differentiation tools can be viewed as black boxes taking as input a program computing the cost functional and giving as output another program computing its gradient. First we derive for the polaron transformed Hamiltonian a Born-Markov master equation using the Bloch-Redfield formalism. By combining the latter with automatic differentiation we are able to implement Z-gate and coherent destruction of tunnelling with high fidelity. Optimization of a dissipative quantum gate poses a more complex numerical problem, since it should occur independent of the input state. To overcome this difficulty, we apply optimal control to the concept of resolvent of the master equation which is the generalisation of quantum unitary evolution operator in the case of dissipative dynamics.
Directional cues affect the collective behaviour of self-propelled particles in one dimension
Authors: Mishra Pawan Kumar , Puitandy Abhra , Mishra Shradha 
Published: August 2024

Abstract
This study explores the effect of quenched disorder on the characteristics of self-propelled particles in one dimension. Here, particles interact with disorder which serve as directional cues. The study investigates how the density of the directional cues influences the emergence of ordering and clustering in the collection of the self-propelled particles. We introduce the microscopic model as well as corresponding coarse-grained equations of motion for the local density and the orientation of particles. Directional cues affect the macroscopic ordering in the system, the size of the ordered clusters decays algebraically with density of cues. Further, in the presence of directional cues, a big macroscopic cluster breaks into small clusters, leading to the localization of particles around it and resulting in high density around the cues.
Fatty Liver Disease Along Cushing Syndrome Evolution
Authors: Marengo Maria , Briet Claire , Munier Mathilde , Boursier Jérôme , Rodien Patrice , Suteau Valentine 
Published: August 2024

Abstract

Context
The clinical manifestations of Cushing syndrome are variable, but an important number of patients present a metabolic syndrome, strongly associated with hepatic steatosis.

Objective
The aim of this study was to determine the prevalence of metabolic dysfunction associated steatotic liver disease (MASLD) at the diagnosis of Cushing syndrome.

Methods
We conducted a single-center retrospective study at Angers Hospital (France) between 2010 and 2020. Forty-nine patients followed for Cushing syndrome with available abdominal imaging at diagnosis were included. A mean liver/spleen density ratio &lt; 1 on computed tomography was diagnostic of hepatic steatosis. Simple clinico-biological scores predictive of hepatic fibrosis (FIB-4, NAFLD Fibrosis Score, and eLIFT) were calculated for patients with hepatic steatosis.

Results
Of the 49 patients, 13 (26.5%) had hepatic steatosis at diagnosis of Cushing syndrome. All 13 had MASLD. These patients had a higher prevalence of type 2 diabetes and higher triglyceride levels in multivariate analysis. There was no difference according to the intensity or duration of Cushing syndrome. Among the 13 patients with MASLD, 2 (15.4%) had a significant fibrosis predictive score. Of the 4 patients with follow-up imaging after remission of Cushing syndrome, 3 had remission of steatosis between 1 and 5 years after remission of Cushing syndrome. No patient without MASLD at diagnosis had a worsening liver/spleen ratio after remission.

Conclusion
We estimated the prevalence of hepatic steatosis at the diagnosis of Cushing syndrome at 26.5%. The presence of metabolic factors was associated with the occurrence of hepatic steatosis.
Is there a relationship between resting state connectivity within large-scale functional networks and implicit motor learning impairments in schizophrenia and bipolar disorder?
Authors: Chrobak Adrian Andrzej , Bielak Sylwia , Nowaczek Dominik , Żyrkowska Aleksandra , Styczeń Krzysztof , Sobczak Anna Maria , Fafrowicz Magdalena , Bryll Amira , Marek Tadeusz , Dudek Dominika , Siwek Marcin 
Published: August 2024

Cel pracyCelem naszego eksploracyjnego badania jest ocena, czy zaburzenia nieświadomego uczenia się motorycznego w schizofrenii (SZ) i w chorobie afektywnej dwubiegunowej (ChaD) są związane z zaburzeniami łączności funkcjonalnej w stanie spoczynku (rs-FC) w obrębie głównych sieci funkcjonalnych ośrodkowego układu nerwowego.MetodaW badaniu uczestniczyło 30 pacjentów z ChAD, 30 z rozpoznaniem SZ i 30 zdrowych ochotników (ZO). Nieświadome uczenie się motoryczne było oceniane przy użyciu zadania z pomiarem seryjnego czasu reakcji (SRTT). Przed treningiem uczestnicy zostali poddani obrazowania funkcjonalnego rezonansu magnetycznego w stanie spoczynku (resting state functional magnetic resonance imaging, rs-fMRI). W badaniu oceniono rs-FC w obrębie sieci istotności (salience network, SAN), sieci aktywności spoczynkowej (default mode network, DMN), sieci czołowo-ciemieniowej (frontoparietal network, FPN), sieci sensoryczno-motorycznej (sensorimotor network, SMN), sieci limbicznej (limbic network) i sieci wzrokowej (visual network, VIN). W pracy analizowano związek między rs-FC powyższych sieci a wskaźnikami nieświadomego uczenia się.Wynikirs-FC w obrębie SAN, DMN, FPN, SMN, LN i VIN nie wykazywała istotnych związków ze wskaźnikami nieświadomego uczenia się motorycznego. Grupy ChAD, SZ i OZ nie różniły się pod względem rs-FC wewnątrz wymienionych sieciWnioskiSiła rs-FC w obrębie głównych sieci funkcjonalnych, tj. SMN, FPN, VIN, LN, SAN i DMN nie wykazywała związku z miarami ocenianymi w SRTT. Niezależność procesu nieświadomego uczenia się motorycznego od spoczynkowej aktywności powyższych sieci stanowi istotną informację dla zrozumienia neuronalnych podstaw tego procesu oraz rozwoju dalszych badań dotyczących tej dziedziny.
Impact of pre-conception diet on female infertility
Authors: Kahan Weronika , Poborowska Dominika , Szafrańska Weronika , Polańska Katarzyna , Wojaczek Marta , Niedbał Piotr , Kosińska Agnieszka , Kras Magdalena , Lelek Katarzyna , Łata Marcin 
Published: August 2024

Introduction and purpose
Infertility is defined as a condition characterized by the inability to become clinically pregnant after 12 months of regular, unprotected sexual intercourse, or because a person's ability to reproduce, either as an individual or with his or her partner, is impaired. Infertility affects between 8% and 12% of couples of reproductive age worldwide. Fertility decline in women begins as early as age 25-30. The purpose of this article is to present the problem of infertility in women, possible diagnostic options, methods of prevention and treatment of infertility. We draw attention to the important role of a proper lifestyle, including diet in the fight against infertility.
State of knowledge
The article reviews the literature on infertility with special attention to the problem of infertility in women. Knowing the causes of infertility, it is possible to implement targeted diagnosis and then treatment. Attention is paid to the influence of proper diet on female fertility.
Material and method
A review of the literature available on PubMed and Google Schoolar was conducted. We focused on presenting different causes of infertility in women, diagnostic options, treatment methods depending on the cause of the problem. We paid special attention to proper diet and its impact on female fertility.
Summary
In our review, we presented how big a problem female infertility is. We managed to describe the current state of knowledge on the definition, epidemiology of fertility and infertility, and the main causes of female infertility. Based on a number of studies, we have proven the beneficial effects of a proper lifestyle with emphasis on a proper diet.
Efektivitas Peran Guru Sekolah Menengah Pertama Katolik (SMPK) Supra Talibura dalam Pembelajaran IPA Kurikulum Merdeka Belajar
Authors: Nurdiyanti Nurdiyanti , Sada Mariana , Fitrah Fitrah 
Published: August 2024

Tujuan penelitian ini untuk mengetahui sistem, kesiapan, dan pelaksanaan pembelajaran IPA dalam kurikulum merdeka belajar. Kurikulum merdeka ini sebagai menggantikan K-13 (kurikulum 2013),ini didasarkan sebagai konsep merdeka belajar dan fokus pada peningkatan kualitas pendidikan. Perubahan kurikulum ini terjadi pada tingkat SMP,namun tidak semua kelas mengalami perubahan hanya kelas VII yang menggunakan kurikulum merdeka belajar. Kurikulum merdeka ini memberikan konsep untuk sekolah menengah pertama dengan "kemerdekaan " bagi pelaksanaan pendidikan terutama para guru dan kepala sekolah dalam mengembangkan,menyusun,dan melaksanakan kurikulum berdasarkan potensi dan kebutuhan peserta didik. Kurikulum merdeka ini membebaskan guru kelas untuk menyusun pembelajaran pada mata pelajaran IPA dengan mempertimbangkan karakteristik. Guru adalah seorang yang mampu mengajar banyak mata pelajaran yang berbeda. Guru juga dituntut untuk senantiasa kreatif dan inovatif dalam proses pembelajaran IPA. Pembelajaran IPA merupakan mata pelajaran yang perlu diajarkan kepada peserta didik sekolah menengah pertama untuk membekali mereka dengan ilmu pengetahuan sistematis yang mempelajari tentang alam,dunia fisik,dan seluruh hal di sekelilingnya,Menurut ( Baharudin,dkk., 2017). Penelitian ini menggunakan metode kualitatif peneliti menggunakan pendekatan untuk menjelaskan pembelajaran IPA di kelas VII SMPK Supra Talibura dapat menggunakan teknik pengumpulan data dengan cara observasi, wawancara, dan dokumentasi. Populasi pada penelitian ini adalah Kepala Sekolah SMPK Supra Talibura, guru kelas VII IPA, dan siswa kelas VII SMPK Supra Talibura. Berdasarkan hasil penelitian yang diperoleh bahwa SMPK Supra Talibura ini sudah menerapkan Kurikulum merdeka belajar sejak tahun 2023 sampe sekarang yang dimana Sekolah ini baru saja menerapkan kurikulum merdeka belajar di kelas VII. Sekolah SMPK Supra Talibura juga sudah mengikuti pelatihan kurikulum merdeka belajar berupa workshop merdeka belajar PMM dan aksi nyata bersama pengawas binaan sekolah . Adapun peran guru kelas VII IPA dalam pembelajaran IPA SMPK Supra Talibura yang dilakukan terhadap peserta didik kelas VII yaitu dengan cara merancang kegiatan pembelajaran outdoor yaitu belajar diluar ruang kelas, mengadakan praktikum yang dimana siswa dilatih merancang dan menemukan sendiri hasil percobaan mereka, dan yang terakhir siswa dilatih untuk membentuk kelompok untuk berdiskusi dan mempresentasikan sehingga ada timbal balik berupa kritik atau pendapat yang kurang setuju.
Etnobotani Rempah Tradisional Masyarakat Adonara Timur Kabupaten Flores Timur
Authors: Juniyati Hastuti , Sada Mariana , Syafriati Yuli Mira 
Published: August 2024

Masyarakat Adonara Timur masih sangat bergantung pada pemanfaatan tumbuhan dalam memenuhi kebutuhan hidup sehari-hari. Salah satu yaitu ritual “bubuk muhuk” menggunakan rempah jahe (Zingiber officinale roscoe) yang masih dilakukan sampai sekarang yaitu pada saat pertandingan sepak bola. Penelitian ini bertujuan untuk mengetahui jenis dan manfaat tumbuhan rempah yang dimanfaatkan oleh masyarakat Adonara Timur Kabupaten Flores Timur. Penelitian ini menggunakan jenis penelitian deskriptif kualitatif dengan teknik pengumpulan data berupa observasi, wawancara, dokumentasi dan identifikasi tumbuhan. Populasi pada penelitian ini adalah Masyarakat kecamatan Adonara Timur (desa Ipi Ebang, desa Lamahala, desa Waiburak). Sampel. Berdasarkan hasil penelitian, diketahui bahwa terdapat sebanyak 16 spesies dari 11 famili tumbuhan rempah yang dimanfaatkan. Bagian tumbuhan yang paling banyak dimanfaatkan yaitu rimpang 57%, batang 13%, umbi 16% dan bagian tumbuhan yang paling sedikit digunakan adalah buah 9%, biji 3%, daun 2%, dan kulit kayu 1%. Persentase tertinggi jenis tumbuhan rempah yang dimanfaatkan oleh masyarakat Adonara Timur Kabupaten Flores Timur adalah jahe (Zingiber officinale roscoe) sebesar 70%, sedangkan presentasi terendah adalah kayu manis (Cinnamomum burmannii blume) sebesar 3%. Cara pemanfaatan tumbuhan rempah yakni digunakan sebagai bumbu masakan, obat tradisional, bahan ritual adat, pewarna kain, pengusir hama,bahan pembuatan minyak. Adapun cara pengolahannya yang beragam yakni dengan dihaluskan, direbus, digeprek, diparut, diseduh, dikunyah dan di rendam. Perolehan tumbuhan rempah-rempah oleh masyarakat Adonara Timur Kabupaten Flores Timur diperoleh dengan cara budidaya, membeli di pasar, ditanam di pekarangan rumah, dikebun atau tumbuh secara liar.
Estimation equation of limb lean soft tissue mass in Asian athletes using bioelectrical impedance analysis
Authors: Lai Yeong-Kang , Ho Chu-Ying , Huang Ai-Chun , Lu Hsueh-Kuan , Hsieh Kuen-Chang 
Published: August 2024

Background
The lean soft tissue mass (LSTM) of the limbs is approximately 63% of total skeletal muscle mass. For athletes, measurement of limb LSTM is the basis for rapid estimation of skeletal muscle mass. This study aimed to establish the estimation equation of LSTM in Asian athletes using bioelectrical impedance analysis (BIA).

Methods
A total of 198 athletes (121 males, 77 females; mean age 22.04 ± 5.57 years) from different sports in Taiwan were enrolled. A modeling group (MG) of 2/3 (n = 132) of subjects and a validation group (VG) of 1/3 (n = 68) were randomly assigned. Using the InBody S-10, resistance and reactance were measured at 50 kHz from the right palm to the right sole while the participant was in the supine position. Predictor variables were height (h), weight (W), age, Sex, Xc, resistance index (RI; RI = h2 / R). LSTM of arms and legs measured by dual-energy X-ray absorptiometry (DXA) was the response variable. Multivariate stepwise regression analysis method was used to establish BIA estimation equations as ArmsLSTMBIA-Asian and LegsLSTMBIA-Asian. Estimation equations performance was confirmed by cross-validation.

Results
Estimation equation "ArmsLSTMBIA-Asian = 0.096 h2/R– 1.132 Sex + 0.030 Weight + 0.022 Xc– 0.022 h + 0.905, r2 = 0.855, SEE = 0.757 kg, n = 132" and "LegsLSTMBIA Asian = 0.197h2/R" + 0.120 h– 1.242 Sex + 0.055 Weight– 0.052 Age + 0.033 Xc –16.136, r2 = 0.916, SEE = 1.431 kg, n = 132" were obtained from MG. Using DXA measurement results of VG for correlation analysis and Limit of Agreement (LOA) of Bland-Altman Plot, ArmsLST is 0.924, -1.53 to 1.43 kg, and LegsLST is 0.957, -2.68 to 2.90 kg.

Conclusion
The established single-frequency BIA hand-to-foot (whole body) estimation equation quickly and accurately estimates LSTM of the arms and legs of Asian athletes.