bluuebunny/crossref_metadata_2025_split huggingface dataset:
Covalent Organic Frameworks: Synthesis and Applications for Photocatalysis
Authors: Shahid Misbah , ur Rehman Aziz , Najam Tayyaba , Majeed Hammad , Shalash Marwan , El‐Bahy Salah M. , Sufyan Javed Muhammad , Shoaib Ahmad Shah Syed , Altaf Nazir Muhammad 
Published: June 2024

AbstractCovalent organic frameworks (COFs), newly developed materials, exhibit considerable promise in the field of catalysis. COFs exhibit captivating catalytic characteristics, including thermal and chemical stability, customizable porosities, and the ability to place active sites flexibly with tunable functions. To establish a connection between structure and activity, this paper provides a thorough justification of the planned creation of covalent organic frameworks for photocatalysis, encompassing H2 production, carbon dioxide reduction, pollutants reduction and transformation of organic substances. We have investigated the catalytic sites that are active within covalent organic frameworks, encompassing the metals, molecular catalysts, and catalyst with single atom (SACs); the reactive skeleton/linkages; and the reactive pendant groups. This exploration aims to establish the benefits of using COF‐based catalysts compared to traditional catalysts. Despite the new advantages, numerous difficulties have also been noted with regard to the future. The objective of this review is to make it easier to design COF‐based composite materials for practical uses.
Effectiveness of direct needle puncture for complete hepaticojejunostomy anastomotic stricture after pancreaticoduodenectomy (with video)
Authors: Soga Koichi , Hayakawa Fuki , Fujiwara Takeshi , Gyotoku Yoshinori , Kusano Yumi , Kobori Ikuhiro , Tamano Masaya 
Published: June 2024

AbstractA 79‐year‐old Japanese woman, who had undergone pancreaticoduodenectomy 6 months prior to presentation owing to pancreatic cancer, complained of jaundice with high fever. Computed tomography revealed proximal bile duct dilatation with complete hepaticojejunostomy anastomotic stricture (HJAS). We performed a single‐balloon endoscopy for biliary drainage. The presence of a scar‐like feature surrounding the anastomosis was identified as the HJAS. White‐light imaging during single‐balloon endoscopy revealed that the HJAS contained a milky whitish area (MWA), suggesting that a membranous and fibrosis layer affected continuous inflammation around the center of the anastomosis (within a scar‐like feature). Endoscopic dilatation was performed using an endoscopic injection needle, with the MWA used as an indicator. A 23‐gauge endoscopic injection needle was used to penetrate the center of the blind lumen within the MWA, and a pinhole was created in the stricture. After confirming the position of the proximal bile duct using a contrast medium with the needle, an endoscopic guidewire with a cannula was inserted into the pinhole. A through‐the‐scope sequential balloon dilator was used to dilate the stricture, and a plastic stent was inserted into the proximal bile duct. This endoscopic intervention led to positive outcomes. In cases of complete HJAS occlusion, an endoscopic approach to the bile duct is difficult because the anastomotic opening of the HJAS is not visible. Thus, puncturing within the MWA, which can be used as a scar‐like landmark within a complete membranous HJAS, is considered a useful endoscopic strategy.
Surgical and radiosurgical treatment of hypothalamic hamartoma: The Italian experience between 2011 and 2021
Authors: Rizzi Michele , Consales Alessandro , Tramacere Irene , De Benedictis Alessandro , Bua Antonella , Specchio Nicola , De Palma Luca , Cognolato Erica , Nobili Lino , Tortora Domenico , Barba Carmen , Pommella Marianna , Giordano Flavio , Pastori Chiara , Marchetti Marcello , Garbelli Rita , Zucchelli Mino , Martinoni Matteo , Ferri Lorenzo , Martucci Matia , Tamburrini Gianpiero , Bianchi Federico , Passamonti Claudia , Di Gennaro Giancarlo , Villani Flavio , Tassi Laura , Marras Carlo 
Published: June 2024

AbstractObjectiveTo investigate the Italian experience on the surgical and radiosurgical treatment of drug‐resistant epilepsy due to hypothalamic hamartoma (HH) in the period 2011–2021 in six Italian epilepsy surgery centers, and to compare safety and efficacy profiles of the different techniques.MethodsWe collected pseudo‐anonymized patient's data with at least 12 months of follow‐up. Surgical outcome was defined according to Engel classification of seizure outcome. Univariate analysis was performed to assess the risk of post‐operative seizures, categorized in dichotomous variable as favorable and unfavorable; explanatory variables were considered. Mann–Whitney or Chi‐squared test were used to assess the presence of an association between variables (p < 0.05).ResultsFull presurgical and postoperative data about 42 patients from 6 epilepsy surgery centers were gathered. Engel class I was reached in the 65.8% and 66.6% of patients with gelastic and non‐gelastic seizures, respectively. Other than daily non‐gelastic seizures were associated with seizure freedom (p = 0.01), and the radiological type presented a trend toward significance (p = 0.12).SignificanceEndoscopic disconnection and laser interstitial thermal therapy are effective in the treatment of HH‐related epilepsy, with a tolerable safety profile. Both gelastic and non‐gelastic seizures can be treated, also in patients with a long history of seizures.Plain Language SummaryThis study collected data about 42 patients with HH‐related epilepsies. Endoscopic disconnection and laser therapy are both effective and safe in the treatment of hypothalamic hamartoma‐related epilepsies.
Numerical simulation of the influence of the structural parameters of a sampling diluter for particulate matter in diesel engines on the internal flow field and dilution ratio
Authors: Geng Limin , Zhao Yang , Sheng Guifen , Gao Nan , Xiao Yonggang , Huang Feichuang , Chen Hao 
Published: June 2024

AbstractThis study investigated how structural parameters (including injection ducts and exhaust nozzle inner diameters) affect the internal flow field and dilution ratio of diesel particulate sampling diluters. Increasing air injection duct diameter increased the injection chamber pressure and decreased the air velocity peak, mixed gas flow velocity, sample temperature, and mixing rate. Excessively small tube diameters caused uneven and discontinuous flow field distributions, while substantial air blockage rendered the flow state poor. Increasing nozzle inner diameters increased the exhaust flow area and the sample temperature, but decreased the velocity of the exhaust and gas mixtures and the pressure drop. Compared with a 2.0 mm inner diameter, 2.5 and 3.0 mm diameters decreased the peak velocity by 11.18% and 14.41%, respectively, and mixing slowed significantly. Inner nozzle diameters of <1.5 mm increased the pressure drop significantly; the exhaust velocity also increased, exceeding the air velocity at the mixing position. The dilution ratio and relative error decreased with increasing inner nozzle diameter. At an air injection duct and an inner nozzle diameter of 0.1 and 2.0 mm, respectively, the dilutor's flow field distribution improved, the mixed gas flow stabilized, and the dilution ratio and relative error were 21.34% and 6.74%, respectively.
Analysis of damage mechanisms and controlling factors of fine particle migration in unconsolidated sandstone reservoirs based on reservoir classification
Authors: Wang Zhao , Yin Hanjun , Tang Haoxuan , Hou Yawei , Yu Hang , Liu Qiang , Tang Hongming 
Published: June 2024

AbstractParticle migration in oil and gas reservoirs is a common phenomenon in the process of oil and gas development, and is considered to be an important reason for the damage of reservoir permeability and the reduction of oil and gas productivity. The mechanism of this phenomenon includes the desorption, migration, and precipitation of particles, which eventually clogs the throat and causes reservoir damage. Therefore, it is necessary to accurately characterize the complex mechanism of particle migration and identify the main controlling factors of particle migration, which is very important for efficient oilfield development and plugging solution. First, the reservoir types are divided into three types and the pore structure models of different types of reservoirs are established. Then, computational fluid dynamics and discrete element coupling method numerical simulation and microscopic visualization of pore throat structure model were combined, to characterize the rules of particles and migration, and analyze the main controlling factors. Finally, a typical model of particle migration and clogging is established. The results show that particle size/throat and particle concentration are the key factors affecting particle plugging, and particle migration has the least effect on the permeability of Type I reservoir and the greatest damage to Type III reservoir. According to the mechanical and hydrodynamic behavior of particles in porous media, three mechanisms and six modes of particle plugging are proposed.
Empowering pharmacists with data: Steps toward proactive medication safety and quality improvement
Authors: Ellinger Lara K. , Bursua Adam , Galanter William , Schiff Gordon D. , Lambert Bruce L. 
Published: June 2024

AbstractPharmacists play a crucial role in medication safety and quality improvement in healthcare, yet face significant challenges due to limited data access, poor data quality, and insufficient data management skills. National pharmacy organizations emphasize the importance of pharmacists using data effectively to improve patient care. This paper suggests several strategies to overcome data challenges, including more widespread adoption of a Chief Pharmacy Informatics Officer (CPIO) role in healthcare institutions, the development and validation of medication safety metrics and dashboards, and the incorporation of data analysis and application skills into pharmacist education and training. The creation of the CPIO position is proposed to lead efforts in data management and use for medication safety. Additionally, establishing clear medication safety metrics and dashboards is recommended to monitor and improve safety practices. To support these roles and tools, enhancing pharmacist training in data analytics is deemed essential. Implementing these strategies aims to empower pharmacists to engage more effectively in proactive medication safety and quality improvement efforts. This approach is expected to address current gaps in data utilization and management, facilitating a more informed method for pharmacists to make healthcare safe for patients.
Combining red photobiomodulation therapy with polydioxanone threads for wrinkle reduction in the glabella region: A randomized, controlled, double‐blind clinical trial
Authors: Garcia Paula Caroline , Meireles Danilo Peron , Tassinary João Alberto Fioravante , Pavani Christiane 
Published: June 2024

AbstractThe combination of polydioxanone (PDO) threads with other technologies has garnered significant interest for rejuvenation purposes. Photobiomodulation (PBM) has the potential to improve patient comfort and recovery after minimally invasive rejuvenation protocols and also contribute to the overall efficacy of these procedures, fostering an integrative approach to cutaneous rejuvenation. The objective os this work was to investigate concurrent application of PDO threads and red LED PBM on glabellar static wrinkles, in a parallel randomized sham‐controlled trial. Forty individuals with Glogau aging classification levels 3 and 4, static glabellar wrinkles, and no significant comorbidities received PDO threads applied along glabellar line. Effective PBM group received 1.35 J and 630 nm red LED light punctually along threads, twice weekly for nine sessions over 30 days. The outcome measures were swelling assessment, dermal thickness and PDO thread degradation via linear ultrasound. No swelling was detected 24 h post‐PDO thread application, hindering PBM effect assessment. PDO threads induced dermal thickening; no added effect with PBM. No significant difference in thread hydrolysis between groups, though some ultrasound records inconclusive on thread presence. The absence of swelling may stem from various factors, including the timing of post‐procedure swelling assessment, operator proficiency in thread application, and procedural characteristics. No evidence supports the notion that PBM augments dermal thickening, however other light parameters should be studied. Insufficient data to demonstrate PBM's effectiveness in controlling post‐procedure swelling. Combination of PBM with PDO thread application doesn't enhance dermal thickening, nor accelerate thread degradation at the parameters used here.
P2RX7 plays a critical role in extracellular vesicle‐mediated secretion of pathogenic molecules from microglia and astrocytes
Authors: Abdullah Mohammad , Ruan Zhi , Ikezu Seiko , Ikezu Tsuneya 
Published: June 2024

AbstractExtracellular vesicle (EV) secretion is mediated by purinergic receptor P2X7 (P2RX7), an ATP‐gated cation channel highly expressed in microglia. We have previously shown that administration of GSK1482160, a P2RX7 selective inhibitor, suppresses EV secretion from murine microglia and prevents tauopathy development, leading to the recovery of the hippocampal function in PS19 mice, expressing P301S tau mutant. It is yet unknown, however, whether the effect of GSK1482160 on EV secretion from glial cells is specifically regulated through P2RX7. Here we tested GSK1482160 on primary microglia and astrocytes isolated from C57BL/6 (WT) and P2rx7–/– mice and evaluated their EV secretion and phagocytotic activity of aggregated human tau (hTau) under ATP stimulation. GSK1482160 treatment and deletion of P2rx7 significantly reduced secretion of small and large EVs in microglia and astrocytes in both ATP stimulated or unstimulated condition as determined by nanoparticle tracking analysis, CD9 ELISA and immunoblotting of Tsg101 and Flotilin 1 using isolated EVs. GSK1482160 treatment had no effect on EV secretion from P2rx7–/– microglia while we observed significant reduction in the secretion of small EVs from P2rx7–/– astrocytes, suggesting its specific targeting of P2RX7 in EV secretion except small EV secretion from astrocytes. Finally, deletion of P2rx7 suppressed IL‐1β secretion and phagocytosed misfolded tau from both microglia and astrocytes. Together, these findings show that GSK1482160 suppresses EV secretion from microglia and astrocytes in P2RX7‐dependment manner, and P2RX7 critically regulates secretion of IL‐1β and misfolded hTau, demonstrating as the viable target of suppressing EV‐mediated neuroinflammation and tau propagation.
Gestational weight gain and adverse birth outcomes in South African women with HIV on antiretroviral therapy and without HIV: a prospective cohort study
Authors: Madlala Hlengiwe P. , Myer Landon , Jao Jennifer , Geffen Hayli , Matjila Mushi , Fisher Azetta , Meyer Demi , Werner Erika F. , Petro Gregory , Cu‐Uvin Susan , McGarvey Stephen T. , Bengtson Angela M. 
Published: June 2024

AbstractIntroductionOutside of pregnancy, evidence shows that persons with HIV initiating or switching to dolutegravir (DTG)‐based antiretroviral therapy (ART) experience greater weight gain compared to those on other ART classes. However, there are few data on the impact of DTG‐based ART on gestational weight gain (GWG) in sub‐Saharan Africa where HIV is most common. According to the National Academy of Medicine (NAM), GWG below and above NAM guidelines is associated with adverse birth outcomes. Therefore, the objective of this study was to describe GWG by HIV status and ART regimen, and examine the associations with adverse birth outcomes.MethodsWe enrolled pregnant women with HIV (WHIV) and without HIV (≥18 years) in a peri‐urban primary healthcare facility in Cape Town, South Africa between 2019 and 2022. GWG was study‐measured at 24–28 (baseline) and 33–38 weeks gestation and converted to GWG rate (kg/week) in accordance with NAM guidelines. GWG z‐scores were generated using the INTEGROWTH‐21 and US standards to account for differing lengths of gestation. Birth outcome data were obtained from medical records. Associations of GWG z‐score with adverse birth outcomes were assessed using multivariable linear or log‐binomial regression.ResultsAmong 292 participants (48% WHIV), median age was 29 years (IQR, 25–33), median pre‐pregnancy body mass index (BMI) was 31 kg/m2 (IQR, 26–36) and 20% were primiparous at baseline. The median weekly rate of GWG was 0.30 kg/week (IQR, 0.12–0.50), 35% had GWG below NAM standards (59% WHIV) and 48% had GWG above NAM standards (36% WHIV). WHIV gained weight more slowly (0.25 vs. 0.37 kg/week, p<0.01) than women without HIV. Weekly rate of GWG did not differ by ART regimen (DTG‐based ART 0.25 vs. efavirenz‐based ART 0.27 kg/week, p = 0.80). In multivariable analyses, GWG z‐score was positively associated with continuous birth weight (mean difference = 68.53 95% CI 8.96, 128.10) and categorical high birth weight of >4000 g (RR = 2.18 95% CI 1.18, 4.01).ConclusionsDespite slower GWG among WHIV, nearly half of all women gained weight faster than recommended by the NAM. GWG was positively associated with infant birth weight. Interventions to support healthy GWG in sub‐Saharan Africa are urgently needed.
Systematic review of family and pediatric constipation: An overlooked piece of the puzzle
Authors: Burton Landon M. , Skelton Joseph , Harry Onengiya , Zuar Lynsey 
Published: June 2024

AbstractThe objective of this review is to summarize pertinent literature looking at family dynamics and/or adherence to treatment in pediatric functional constipation. A structured systematic literature search was conducted on MEDLINE, Embase, and Web of Science core collection libraries from the years 2000 to 2023 using specific search terms: constipation, treatment adherence, family dynamics, parenting style, and pediatrics. Seventy‐one publications were identified and included for review. After screening based on alignment to the review, 20 publications remained. These publications were placed into three categories depending on their intent and findings: (1) recommendations to further increase adherence, (2) studies analyzing factors of adherence, and (3) studies stating a need for a better understanding of family factors. A future area of research is identifying the associations between family factors on adherence to constipation treatment regimens. Results from such studies would increase the amount of positive treatment outcomes and decrease unnecessary healthcare costs.
Fatty acid composition as a function of latitude in barnacle cyprid larvae
Authors: Leal Inês , Thyrring Jakob , Flores Augusto A. V. , Archambault Philippe , Collin Rachel , Sejr Mikael K. , Scrosati Ricardo A. , Tremblay Réjean 
Published: June 2024

AbstractBroadly distributed species need to perform well in a range of environmental conditions, but knowledge of how wide‐ranging marine larvae perform along latitudinal gradients remains limited. The fatty acid composition of larvae is important for their physiological responses to changing conditions. Here, we investigated the fatty acid composition of the last, non‐feeding stage of barnacle larvae (cyprids) using an integrative (larvae–environment) and comparative (latitudinal) approach. We measured fatty acids in the pelagic particulate matter and cyprids from Chthamalus bisinuatus, Chthamalus proteus, and Semibalanus balanoides from tropical to polar (Arctic) latitudes to identify potential food sources during the feeding larval stages (nauplius) that precede the cyprids and to ascertain larval capacity to integrate neutral (energetic) and polar (structural) fatty acids. We demonstrate that particulate matter in tropical waters mainly consisted of low‐quality saturated fatty acids derived from detrital pathways, while particulate matter from polar waters was rich in polyunsaturated fatty acids originating from living microalgae. Across the studied regions, neutral fatty acids were assimilated from various food sources including diatoms, dinoflagellates, detritus, and microeukaryotes. Cyprids consistently retained higher essential fatty acid levels than the relative share in the particulate matter. Particularly, the essential docosahexaenoic acid (22:6ω3), which was scarce in the particulate matter, was highly retained across all species but highest for the tropical cyprids. We argue that this latitudinal pattern in fatty acid retention is related to periods of reduced nutrient intake, increased energetic and/or synthetic requirements, and responses to physical large‐scale differences in environmental conditions.
Investigating the effects of food insecurity, self‐efficacy, and locus of control on obesity in an emerging markets
Authors: Arli Denni , Pekerti Andre , Siaputra Ide , Bogomolova Svetlana , Rundle‐Thiele Sharyn 
Published: June 2024

AbstractIncreasing rates of obesity are affecting many countries around the world, including developing regions such as Indonesia. One of the factors contributing to obesity is a lack of food security, which involves a lack of control over when food will be available. Food insecurity is linked to low self‐efficacy and can lead consumers to overeat high‐energy‐density foods and drinks when available. This research empirically tested the relationships between people's intention to diet and exercise with the locus of control and general and specific health self‐efficacy resulting from the lack of food security in Indonesia, employing a mixed‐methods approach comprising a qualitative approach in Study 1 (n = 23) and a quantitative approach in Study 2 (n = 1494). The results indicate that study participants were struggling to maintain healthy diets and lifestyles and attempted various strategies to compensate for their poor diets. Moreover, the results suggest that food insecurity negatively influences individuals' self‐efficacy, subsequently influencing people's intention to exercise and eat healthily. Our findings carry important policy implications for developing economies. Governments should ensure the availability of nutritious food for their populations, especially for the poor. Predictable, nutritionally sound foods are essential to prevent overeating high‐energy‐density foods. We recommend that governments develop mixed downstream and midstream approaches, such as mentoring programs, to develop self‐efficacy and address obesity.
P‐3.4: Plenoxels‐based Parallax Map Generation for Flexible Scale Ultra‐High Resolution in 3D Imaging
Authors: Yang Changwei , Xiao Min , Jia Han , Xu Yunfei , Duan Hongji , Liu Xiaomin 
Published: June 2024

This study is devoted to the development of a neural network‐free radial field flexible scale ultra‐high resolution parallax map generation method to improve the generation of ultra‐high resolution parallax maps for naked eye 3D display. In naked eye 3D display, the acquisition of parallax maps is crucial, the traditional method is to shoot the object by camera array, which requires high hardware conditions, in recent years, with the advancement of technology, the generation of parallax maps by Nerf has appeared, but this method generates lower quality images and requires a longer time to train the model, with a single GPU training taking more than one hour.In this paper, we propose a method to generate parallax maps based on neural network‐free radial field and arbitrary scale super‐resolution, firstly, we generate sparse voxel mesh by neural network‐free radial field (Plenoxels), and the optimization time on a single Titan RTX GPU is more than ten minutes, and then we get parallax maps by setting up a virtual camera, however, the parallax maps obtained are low‐resolution and can't match with the size of the naked‐eye 3D displays, therefore, we introduce an arbitrary scale super‐resolution network for the parallax maps, and we get high‐resolution parallax maps and can match the size of the naked‐eye 3D displays.