bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ocena odporności na propagację spękań mieszanek SMA z granulatem asfaltowym
Authors: Stokfisz Anita , Liphardt Adam 
Published: July 2024

Konieczność okresowej wymiany warstw ścieralnych w tym z mieszanek typu SMA wiąże się z możliwością pozyskania i ponownego wykorzystania wysokiej jakości destruktu asfaltowego. Dotychczas problem stosowania destruktu oraz granulatu asfaltowego do mieszanek typu SMA nie był przedmiotem szerokich analiz i badań. Wdrażanie zasad gospodarki o obiegu zamkniętym wymusi w najbliższym czasie upowszechnienie stosowania granulatu asfaltowego również do mieszanek typu SMA. W procesie wymiany warstwy ścieralnej nowa mieszanka mineralno-asfaltowa układana jest na istniejącej warstwie wiążącej, w której na skutek wcześniejszej eksploatacji mogą występować m.in. mikrospękania, które w okresie dalszego użytkowania nawierzchni będą propagować również do nowo wykonanej warstwy ścieralnej. Mieszanka SMA powinna zatem charakteryzować się odpornością na propagację spękań z niższych warstw asfaltowych. Zastosowanie w mieszance SMA materiału z recyklingu, zawierającego postarzone lepiszcze asfaltowe może przyczyniać się do zmniejszenia odporności na pękanie. Założono, że właściwości mieszanki mineralno-asfaltowej mogą być kształtowane m.in. poprzez modyfikację parametrów procesu produkcyjnego mieszanki. Analizie poddano wpływ wybranych warunków technologicznych wytwarzania mieszanek SMA z granulatem asfaltowym na ich odporność na propagacje spękań ocenianą metodą SCB. Badaniom poddano dwie mieszanki mineralno-asfaltowe typu SMA 11 o zawartości granulatu asfaltowego 20% oraz 40% m/m wytwarzane w technologii dozowania granulatu asfaltowego na gorąco. Na podstawie analizy uzyskanych wyników wykazano, że zarówno przyjęty schemat dozowania składników mieszanki, jak i zawartość granulatu asfaltowego mają istotny wpływ na uzyskiwane wartości parametrów charakteryzujących odporność na pękanie mieszanki mineralno-asfaltowej.
Adverse events of hypodermoclysis in cancer patients under palliative care: scoping review / Eventos adversos da hipodermóclise em pacientes oncológicos sob cuidados paliativos: revisão de escopo
Authors: Ferraciolli Clarissa , Quispe Mendoza Isabel Yovana , De Souza Raquel Eustáquia , Nogueira de Almeida Márcia , Falci Ercole Flávia , Vieira Toledo Luana 
Published: July 2024

Objetivo : mapear as evidências científicas sobre os eventos adversos locais decorrentes do uso da hipodermóclise em pacientes oncológicos sob cuidados paliativos. Método : revisão de escopo baseada nas diretrizes Prisma, cuja busca foi realizada nas bases de dados: Portal Regional da Biblioteca Virtual em Saúde; Biblioteca Nacional de Medicina ; Biblioteca Cochrane , Scopus, Web of Science e Embase via Portal de periódicos da Capes. Resultados : os eventos adversos mais relatados nos estudos foram eritema, edema, desconforto no local, abcesso e sangramento. Considerações finais : a hipodermóclise é uma técnica útil e segura para hidratação e administração de medicamentos em pacientes oncológicos em cuidados paliativos, porém apresenta eventos adversos que precisam ser mais bem esclarecidos.
Robust adaptive dynamic surface control for linear time‐varying systems
Authors: Song Mingchao , Lin Yan , Huang Ran 
Published: June 2013

SUMMARYIn this paper, robust output‐feedback tracking control is considered for a class of linear time‐varying plants whose time‐varying parameters are unknown bounded with bounded derivatives and output is affected by unknown bounded additive disturbances. Using adaptive dynamic surface control technique, the proposed scheme possesses the following advantages: (1) the design procedure is simple and the control law is easy to be implemented, and (2) by introducing an initialization technique, together with adjusting some design parameters, the  performance of system tracking error can be guaranteed regardless of the time variation. It is proved that with the proposed scheme, all the closed‐loop signals are semi‐globally uniformly ultimately bounded. Simulation results are presented to demonstrate the effectiveness of the proposed scheme. Copyright © 2013 John Wiley & Sons, Ltd.
Tuning Magnetic Property and Autophagic Response for Self‐Assembled Ni–Co Alloy Nanocrystals
Authors: Dong Liang , Liu Yun , Lu Yang , Zhang Li , Man Na , Cao Liang , Ma Kai , An Duo , Lin Jun , Xu Yun‐Jun , Xu Wei‐Ping , Wu Wen‐Bin , Yu Shu‐Hong , Wen Long‐Ping 
Published: June 2013

AbstractInduction of autophagy is a common response of cells upon exposure to nanomaterials and represents both a safety concern and an application niche for engineered nanomaterials. Herein, it is reported that the magnetic property and the autophagy‐inducing activity for Ni–Co alloy nanocrystal (NC) assemblies can be differentially “tuned” through altering the material composition. A series of Ni–Co alloy NC assemblies, composed of nanoparticles (NPs) with a size of about 30 nm, can be quickly synthesized under microwave irradiation in aqueous solution. A controllable self‐assembling effect is observed due to the strong magnetic moment of NPs and external magnetic field. Interestingly, the saturation magnetization (Ms) shows a ‘roller coaster’ effect with varying component molar ratio, while the autophagy‐inducing activity and toxicity of these alloy NCs presents an elevated tendency with the increase of nickel component. The autophagic response partly contributes to the observed cellular toxicity of the NC assemblies, as inhibition of autophagy partially but significantly reduces toxicity. Therefore, through tuning the composition of the alloy, optimal Ni–Co NCs satisfying the needs of different applications such as diagnostic imaging (maximum magnetization and low autophagic response) or magnetically‐directed cancer cell killing (maximum autophagic response and sufficient magnetization) may be designed and developed.
Host–Guest Supramolecular Nanosystems for Cancer Diagnostics and Therapeutics
Authors: Wang Lei , Li Li‐li , Fan Yun‐shan , Wang Hao 
Published: June 2013

AbstractExtensive efforts have been devoted to the construction of functional supramolecular nanosystems for applications in catalysis, energy conversion, sensing and biomedicine. The applications of supramolecular nanosystems such as liposomes, micelles, inorganic nanoparticles, carbon materials for cancer diagnostics and therapeutics have been reviewed by other groups. Here, we will focus on the recent momentous advances in the implementation of typical supramolecular hosts (i.e., cyclodextrins, calixarenes, cucurbiturils and metallo‐hosts) and their nanosystems in cancer diagnostics and therapeutics. We discuss the evolutive process of supramolecular nanosystems from the structural control and characterization to their diagnostic and therapeutic function exploitation and even the future potentials for clinical translation.
Preparation and properties of polystyrene–γ‐methacryloxypropyl trimethoxy silane copolymer/zirconia nanohybrid materials
Authors: Tong Mingkang , Yu Juan , Song Jianzhi , Qi Rongrong 
Published: June 2013

ABSTRACTPolystyrene (PS)–γ‐methacryloxypropyl trimethoxy silane (MPTMS) copolymer/zirconia (ZrO2) nanohybrid materials were successfully prepared by the combination of solvothermal and in situ synthesis methods, in which the comonomer was used as chemical bonding agent between the nanoparticles and the matrix, and acetylacetone (AcAc) was used as a size control agent of ZrO2 in the PS matrix. Then, a new transparency film with a relatively high refractive index (1.72) was successfully obtained, in which ZrO2 could be dispersed well in the PS–MPTMS matrix. Field emission scanning electron microscopy images indicated that AcAc was helpful in the dispersion of the nanoparticles, and smaller ZrO2 particles with no aggregation were obtained in the PS–MPTMS matrix. The structure and thermal properties of the hybrid films were investigated by Fourier transform infrared spectroscopy and thermogravimetric analysis, and the surface properties were also examined. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 130: 2320–2327, 2013
Spatio‐Temporal Heterogeneity: Concepts and Analyses by DUTILLEUL, P.R.L.
Authors: Zhu Jun 
Published: June 2013

AbstractEDITOR: TAESUNG PARKSpatio‐Temporal Heterogeneity: Concepts and Analyses(P.R.L. Dutilleul)Jun ZhuProgramming Graphical User Interfaces(M.L. Lawrence and J. Verzani)Fernando TusellSimultaneous Inference in Regression(W. Liu)Aldo Solari
Understanding mild acid pretreatment of sugarcane bagasse through particle scale modeling
Authors: Greenwood Ava A. , Farrell Troy W. , O'Hara Ian M. 
Published: June 2013

ABSTRACTSugarcane bagasse is an abundant and sustainable resource, generated as a by‐product of sugarcane milling. The cellulosic material within bagasse can be broken down into glucose molecules and fermented to produce ethanol, making it a promising feedstock for biofuel production. Mild acid pretreatment hydrolyses the hemicellulosic component of biomass, thus allowing enzymes greater access to the cellulosic substrate during saccharification. A particle‐scale mathematical model describing the mild acid pretreatment of sugarcane bagasse has been developed, using a volume averaged framework. Discrete population‐balance equations are used to characterise the polymer degradation kinetics, and diffusive effects account for mass transport within the cell wall of the bagasse. As the fibrous material hydrolyses over time, variations in the porosity of the cell wall and the downstream effects on the reaction kinetics are accounted for using conservation of volume arguments. Non‐dimensionalization of the model equations reduces the number of parameters in the system to a set of four dimensionless ratios that compare the timescales of different reaction and diffusion events. Theoretical yield curves are compared to macroscopic experimental observations from the literature and inferences are made as to constraints on these “unknown” parameters. These results enable connections to be made between experimental data and the underlying thermodynamics of acid pretreatment. Consequently, the results suggest that data‐fitting techniques used to obtain kinetic parameters should be carefully applied, with prudent consideration given to the chemical and physiological processes being modeled. Biotechnol. Bioeng. 2013;110: 3114–3125. © 2013 Wiley Periodicals, Inc.
Caffeic acid production enhancement by engineering a phenylalanine over‐producing Escherichia coli strain
Authors: Huang Qin , Lin Yuheng , Yan Yajun 
Published: June 2013

ABSTRACTCaffeic acid is a plant‐specific phenylpropanoic acid with multiple health‐improving effects reported, and its therapeutic derivatives have also been studied throughout the last decade. To meet its market need and achieve high‐level production, microbial production of caffeic acid approaches have been developed in metabolically engineered Escherichia coli. In our previous work, we have established the first artificial pathway that realized de novo production of caffeic acid using E. coli endogenous 4‐hydroxyphenylacetate 3‐hydroxylase (4HP3H). In this work, we exploited the catalytic potential of 4HPA3H in the whole‐cell bioconversion study and produced 3.82 g/L (461.12 mg/L/OD) caffeic acid from p‐coumaric acid, a direct precursor. We further engineered a phenylalanine over‐producer into a tyrosine over‐producer and then introduced the artificial pathway. After adjusting the expression strategy and optimizing the inoculants timing, de novo production of caffeic acid reached 766.68 mg/L. Both results from the direct precursor and simple carbon sources represent the highest titers of caffeic acid from microbial production so far. Biotechnol. Bioeng. 2013;110: 3188–3196. © 2013 Wiley Periodicals, Inc.
The distribution of influence in purchase decisions by male homosexual couples
Authors: Schneider Helmut , Schönenberg Ines , Ferié Frederik 
Published: June 2013

ABSTRACTThe purchase decisions of families are of great interest to marketing researchers, yet families also have become increasingly multi‐faceted, especially in Western societies, where non‐traditional families are far more prevalent and evident in public and business life than they once were. Even as it attempts to adapt to some changes, marketing has not kept up with every development; homosexual couples in particular remain poorly researched. This article therefore examines which factors affect the distribution of influence between partners in male homosexual, long‐term relationships when they make purchase decisions. In line with some extant predictions, male homosexual families tend to use highly egalitarian processes to make purchase decisions. Sex‐role orientation generally does not significantly affect the distribution of influence. In contrast with prior work, this study also shows that a partner's resources affect his relative influence. The investigation demonstrates that some conflict resolution styles employed by partners have significant effects on influence distribution in the context of purchase decisions by male homosexual couples. By providing insights into the purchase decision‐making of male homosexual couples, this research broadens the understanding of homosexual consumers in general. Moreover, the findings about the effect of conflict resolution styles on the influence distribution in male homosexual couples adds significantly to consumer research. Copyright © 2013 John Wiley & Sons, Ltd.
Skeletal muscle density predicts prognosis in patients with metastatic renal cell carcinoma treated with targeted therapies
Authors: Antoun Sami , Lanoy Emilie , Iacovelli Roberto , Albiges‐Sauvin Laurence , Loriot Yohann , Merad‐Taoufik Mansouriah , Fizazi Karim , di Palma Mario , Baracos Vickie E. , Escudier Bernard 
Published: June 2013

BACKGROUNDStudies have shown that skeletal muscle and adipose tissue are linked to overall survival (OS) and progression‐free survival (PFS). Because targeted therapies have improved the outcome in patients with metastatic renal cell carcinoma (mRCC), new prognostic parameters are required. The objective of the current study was to analyze whether body composition parameters play a prognostic role in patients with mRCC.METHODSAdipose tissue, skeletal muscle, and skeletal muscle density (SMD) were assessed with computed tomography imaging by measuring cross‐sectional areas of the tissues and mean muscle Hounsfield units (HU). A high level of mean HU indicates a high SMD and high quality of muscle. OS and PFS were estimated using the Kaplan‐Meier method and compared with the log‐rank test. The multivariable Cox proportional hazards model was adjusted for Heng risk score and treatment.RESULTSIn the 149 patients studied, the median OS was 21.4 months and was strongly associated with SMD; the median OS in patients with low SMD was approximately one‐half that of patients with high SMD (14 months vs 29 months; P = .001). After adjustment for Heng risk score and treatment, high SMD was associated with longer OS (hazards ratio, 1.85; P = .004) and longer PFS (hazards ratio, 1.81; P = .002). Adding SMD will separate the intermediate‐risk and favorable‐risk groups into 3 groups, with different median OS periods ranging from 8 months (95% confidence interval [95% CI], 6 months‐12 months) for an intermediate‐risk Heng score/low SMD to 22 months (95% CI, 14 months‐27 months) for an intermediate‐risk Heng score/high SMD and a favorable‐risk Heng score/low SMD to 35 months (95% CI, 24 months‐43 months) for a favorable‐risk Heng score/high SMD.CONCLUSIONSHigh muscle density appears to be independently associated with improved outcome and could be integrated into the prognostic scores thereby enhancing the management of patients with mRCC. Cancer 2013;119:3377–84. © 2013 American Cancer Society.
Linking Environmental Citizenship and Civic Engagement to Public Trust and Environmental Sacrifice in the Asian Context
Authors: Jin Myung H. , Shriar Avrum J. 
Published: June 2013

ABSTRACTDespite the increasing interest in collaborative governance, existing literature on the subject focuses mostly on what government can do for citizens while ignoring the roles of citizens. Utilizing data from the 2010 International Social Survey Program on an environment this study builds on previous work on the link between citizen participation and public trust by comparing the effects of environmental citizenship and other methods of civic engagement on trust in government and on citizens’ willingness to sacrifice for environmental causes. The main findings suggest that while environmental citizenship is generally a consistent predictor of both public trust in government and citizens’ willingness to sacrifice for environmental causes, civic engagement experience was significantly associated only with enhancing willingness to sacrifice for environmental causes. Implications are discussed. Copyright © 2013 John Wiley & Sons, Ltd and ERP Environment.
A Multi‐Component Reaction in the Morita­–Baylis–Hillman Route
Authors: Pal Sudhir Chandra , Bhunia Sankar Chandra 
Published: June 2013

AbstractA facile stereoselective synthesis of trisubstituted (Z)/(E)‐alkenes containing a functionalized thioether unit has been accomplished by using a new three‐component tetramolecular reaction (ABCB′‐type) following a Morita–Baylis–Hillman (MBH) route. Syntheses beginning with preformed MBH adducts yield similar results (ABC‐type reaction) and broaden the scope of application. Suitably substituted aromatic aldehydes result in the formation of 3‐substituted‐2H‐thiochromenes in high yield.
Synthesis of Phosphonoglycine Backbone Units for the Development of Phosphono Peptide Nucleic Acids
Authors: Doboszewski Bogdan , Groaz Elisabetta , Herdewijn Piet 
Published: June 2013

AbstractA series of phosphono‐modified backbone mimics based on achiral and chiral N‐(dihydroxypropyl)glycine units were obtained by sequential addition of phosphonate and nucleobase moieties to suitably protected dihydroxypropylamines. Simple synthetic strategies enabled the preparation of various target derivatives that will be useful as building blocks for the preparation of new synthetic polymers containing a phosphonate internucleotide linkage in place of the standard phosphodiester bond.
Determination of Sulfide by Hematoxylin Multiwalled Carbon Nanotubes Modified Carbon Paste Electrode
Authors: Long Vu Dai , Červenka Libor 
Published: June 2013

AbstractThis study investigates a new approach for the amperometric determination of sulfide using a hematoxylin multiwalled carbon nanotubes modified carbon paste electrode (HM‐MWCNTs/CPE). The experimental results show that HM‐MWCNTs/CPE significantly enhances the electrocatalytic activity towards sulfide oxidation. Cyclic voltammetric studies show that the peak potential of sulfide shifted from +400 mV at unmodified CPE to +175 mV at HM‐MWCNTs/CPE. The currents obtained from amperometric measurements at optimum conditions were linearly correlated with the concentration of sulfide. The calibration curve was obtained for sulfide concentrations in the range of 0.5–150×10−6 mol L−1. The detection limit was found to be 0.2×10−6 mol L−1 for the amperometric method. The proposed method was successfully applied to a river water sample in Pardubice, Czech Republic.
Short‐Term Forecasts of French GDP: A Dynamic Factor Model with Targeted Predictors
Authors: Bessec Marie 
Published: June 2013

ABSTRACTIn recent years, factor models have received increasing attention from both econometricians and practitioners in the forecasting of macroeconomic variables. In this context, Bai and Ng (Journal of Econometrics 2008; 146: 304–317) find an improvement in selecting indicators according to the forecast variable prior to factor estimation (targeted predictors). In particular, they propose using the LARS‐EN algorithm to remove irrelevant predictors. In this paper, we adapt the Bai and Ng procedure to a setup in which data releases are delayed and staggered. In the pre‐selection step, we replace actual data with estimates obtained on the basis of past information, where the structure of the available information replicates the one a forecaster would face in real time. We estimate on the reduced dataset the dynamic factor model of Giannone et al. (Journal of Monetary Economics 2008; 55: 665–676) and Doz et al. (Journal of Econometrics 2011; 164: 188–205), which is particularly suitable for the very short‐term forecast of GDP. A pseudo real‐time evaluation on French data shows the potential of our approach. Copyright © 2013 John Wiley & Sons, Ltd.
Influence of water and sediment supply on the long‐term evolution of alluvial fans and deltas: Statistical characterization of basin‐filling sedimentation patterns
Authors: Straub Kyle M. , Wang Yinan 
Published: June 2013

AbstractThe temporal and spatial variability of sedimentation, resulting from sediment storage and release and the lateral mobility of sediment transporting flows, imparts fundamental patterns into the stratigraphic record. Recent studies show that paleoenvironmental (allogenic) signals preserved in stratigraphy may be contaminated by internally generated (autogenic) sedimentation patterns; however, it is unclear how the magnitude of autogenic dynamics is related to allogenic forcings. Utilizing statistical methods, we quantify basin‐filling trends in three laboratory experiments where input water and sediment flux were varied. We use the compensation index and compensation time scale to estimate the strength of compensation, defined here as the tendency to fill topographic lows faster than would result from random deposit stacking, and to estimate the time scales over which autogenic processes operate. In the experiments, topography of channelized deltas formed by noncohesive sediment was monitored in a basin experiencing temporally and spatially uniform relative subsidence. Each experiment resulted in construction of a stratigraphic package in excess of 25 channel depths thick. We find that compensation strength in the experiments is not influenced by absolute magnitudes of water and sediment flux but does increase as a function of the ratio of water to sediment flux. A compensation time scale, defined as the maximum depth of a system's channels divided by the long‐term deposition rate, accurately defines the maximum time scale at which autogenic dynamics occur in all experiments. When applied to field‐scale systems, we predict that autogenic dynamics occur out to time scales between 5 and 150 kyr.
Twenty‐first century changes in daily temperature variability in CMIP3 climate models
Authors: Ylhäisi Jussi S. , Räisänen Jouni 
Published: June 2013

AbstractChanges in the daily mean surface air temperature distribution between the time periods 1981–2000 and 2081–2100 in 15 climate model simulations participating in the Third Coupled Model Intercomparison Project (CMIP3) are analysed. Variability is defined by first removing the annual cycle after which the range and skewness of the temperature distribution are calculated. Present‐day biases for the different aspects of the distribution are also studied, using the ERA‐Interim reanalysis as the main reference dataset. The variability in the simulations compared to reanalysis is generally smaller over oceans and larger over land areas. For skewness of the temperature distribution, inter‐model variability is much larger and systematic model biases are more local. Model performance regarding the mean values is potentially a good indicator of the model performance for range, but for skewness this relation is weaker. For future changes in the range of daily temperature variability, the models agree best over the Northern Hemisphere mid‐ to high‐latitude land areas, where variability is simulated to decrease. Elsewhere, the inter‐model differences are generally larger than the multi‐model mean changes. Near the sea ice border, significant negative correlations are found between the changes in mean temperature and the temperature range. For changes in skewness, the signal‐to‐noise ratio is very low over most areas and no firm conclusions can be drawn from the ensemble results. Our results are relatively insensitive to the precise definition of the range and skewness metrics and to internal variability of climate.