bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Construction of Instrumental Music Teacher Identity
Authors: Natale-Abramo Melissa 
Published: July 2015

Abstract
The purpose of this qualitative multiple case study is to uncover various discourses that constituted the identity construction of three instrumental music teachers. I apply a poststructural theoretical framework--particularly the ideas of discourse, discursive field, and performativity--and narrative analysis to uncover a variety of discourses that shape music teacher identity. The data I collected includes interviews, journal entries, and observations of three band teachers over the course of one school year. I employ narrative analysis to analyze data and to uncover how the participants constructed their music teacher identities in the practice of teaching. I identified four themes related to the construction of their music teacher identities: (a) pedagogical discourses that conflict, (b) subordination of music as a discipline, (c) negotiation of class and race, and (d) performativity of sexuality. The findings suggest that these discourses constitute the performativity of instrumental music teacher identity and have implications for music teacher education and music teacher identity research.
Machine learning models for outcome prediction in thrombectomy for large anterior vessel occlusion
Authors: Shirvani Omid , Warnat‐Herresthal Stefanie , Savchuk Ivan , Bode Felix J. , Nitsch Louisa , Stösser Sebastian , Ebrahimi Taraneh , von Danwitz Niklas , Asperger Hannah , Layer Julia , Meissner Julius , Thielscher Christian , Dorn Franziska , Lehnen Nils , Schultze Joachim L. , Petzold Gabor C. , Weller Johannes M. ,   the GSR‐ET Investigators
Published: August 2024

AbstractObjectivePredicting long‐term functional outcomes shortly after a stroke is challenging, even for experienced neurologists. Therefore, we aimed to evaluate multiple machine learning models and the importance of clinical/radiological parameters to develop a model that balances minimal input data with reliable predictions of long‐term functional independency.MethodsOur study utilized data from the German Stroke Registry on patients with large anterior vessel occlusion who underwent endovascular treatment. We trained seven machine learning models using 30 parameters from the first day postadmission to predict a modified Ranking Scale of 0–2 at 90 days poststroke. Model performance was assessed using a 20‐fold cross‐validation and one‐sided Wilcoxon rank‐sum tests. Key features were identified through backward feature selection.ResultsWe included 7485 individuals with a median age of 75 years and a median NIHSS score at admission of 14 in our analysis. Our Deep Neural Network model demonstrated the best performance among all models including data from 24 h postadmission. Backward feature selection identified the seven most important features to be NIHSS after 24 h, age, modified Ranking Scale after 24 h, premorbid modified Ranking Scale, intracranial hemorrhage within 24 h, intravenous thrombolysis, and NIHSS at admission. Narrowing the Deep Neural Network model's input data to these features preserved the high performance with an AUC of 0.9 (CI: 0.89–0.91).InterpretationOur Deep Neural Network model, trained on over 7000 patients, predicts 90‐day functional independence using only seven clinical/radiological features from the first day postadmission, demonstrating both high accuracy and practicality for clinical implementation on stroke units.
Fullerene‐Based Immunoregulatory Nanomaterials for Immunotherapy of Tumor and Immune‐Related Inflammatory Diseases
Authors: Zhen Mingming , Xu Yuan , Wang Chunru , Bai Chunli 
Published: August 2024

AbstractImmunoregulatory strategies for activating or inhibiting immune responses have emerged as a promising approach for treating tumors and immune‐related inflammatory diseases. Nanomaterials, also known for their inherent immunoregulatory capacity, are extensively investigated for their potential in immunotherapy. Among these immunoregulatory nanomaterials, fullerene‐based nanomaterials with unique immunoregulatory properties have attracted considerable attention for their use in immunotherapy. In this study, a comprehensive review of the recent research progress on fullerene‐based immunoregulatory nanomaterials is presented. It illustrates the specific mechanism of immune activation using fullerene nanomaterials and reviews their applications in tumor immunotherapy and tumor‐enhancement immunotherapy. Now It introduces the molecular mechanism of fullerene nanomaterials for inhibiting over‐activated inflammation. Herein, different negative immunoregulatory strategies are developed using fullerene nanomaterials to inhibit immune‐related inflammatory diseases. Additionally, the current challenges and prospects for developing efficient clinical usage of fullerene‐based immunoregulatory nanomaterials are discussed.
Synergistic Toughening and Strain Releasing Strategy in Metal Halide Perovskite Photovoltaics
Authors: Wang Chenyun , Shang Chuanzhen , Feng Haoyang , Lei Yudong , Qu Duo , Zhou Bin , Zhang Xinyue , Hu Hanwei , Zhang Yajie , Zhang Zhanfei , Li Bin , Bao Zheng , Ye Fengjun , Zheng Zebang , Wang Zhenhua , Sun Lijie , Tu Yongguang 
Published: August 2024

AbstractMetal halide perovskite with high Young's modulus is prone to form cracks when subjected to mechanical stresses such as bending, twisting, or impacting, ultimately leading to a permanent decline in the performance of their photovoltaic devices. These mechanical properties pose challenges to the durability of long‐term service of photovoltaic devices and the production of flexible devices. To address this issue, the poly (lipoic acid‐co‐Styrene) elastomer is employed to modulate the modulus of perovskite films. The peak force quantitative nanomechanical atomic force microscopy measurements and nanoindentation tests demonstrated a reduction in modulus, with the lower modulus preventing the formation of cracks and defects during deformation. Moreover, this approach also suppressed the non‐radiative recombination of perovskite solar cells by leveraging the interaction between functional groups and defects. Through this method, the rigid inverted devices attained a power conversion efficiency of 24.42% alongside remarkable stability. Concurrently, flexible inverted devices achieved a power conversion efficiency of 22.21%. This strategy offers a promising avenue for fabricating flexible perovskite solar cells and enhancing their mechanical durability.
Rapid Regeneration of Graphite Anodes via Self‐Induced Microwave Plasma
Authors: Shan Minghui , Xu Shuchang , Cao Yunteng , Han Bing , Zhu Xiaoqing , Zhang Tao , Dang Chenyang , Zhu Jiacheng , Zhou Qi , Xue Zhixin , Xu Yaping , Zhu Qixuan , Islam Md Shariful , Yin Ben Hang , Chang Xijiang , Cao Changyong (Chase) , Xu Guiyin , Zhu Meifang 
Published: August 2024

AbstractBattery recycling is a promising approach to mitigate the safety, environmental, and economic threats posed by numerous discarded lithium‐ion batteries (LIBs). However, the unclear atomic‐scale degradation of spent graphite complicates recycling, resulting in energy‐intensive impurity removal and graphitization, which hampers industrialization. This study uses Cryo‐transmission electron microscopy (Cryo‐TEM) to characterize spent graphite degradation and develop a scalable graphite self‐induced microwave plasma method for efficient regeneration. Cryo‐TEM images show graphite coated with a solid electrolyte interphase (SEI) layer, revealing lattice defects and structure expansion near the surface that impair electrochemical performance. The self‐induced microwave plasma method eradicates the SEI layer and restores the graphite lattice structure within 30 s. Multiphysics simulations indicate that the microwave field generates a strong electric field on the graphite surface, causing plasma discharge and rapid surface heating. Regenerated graphite demonstrates excellent electrochemical performance, with a specific charge capacity of 352.2 mAh g−1 at 0.2 C and ≈81% capacity retention after 400 cycles, matching commercially available materials. This efficient method offers a promising approach for recycling graphite anodes.
In Situ Synthesis of Polyamidoxime Chains Inside the Negative‐Charged Confining Fields for Efficient Adsorption of Uranyl Ions
Authors: Cao Doudou , Cui Fengchao , Zhang Cheng , Song Yingbo , Zheng Yue , Cao Jiarui , Yuan Ye , Yang Yajie 
Published: August 2024

AbstractPolyamidoxime (PAO) and its derivatives are widely regarded as promising adsorbents for uranium extraction from seawater. However, their close‐packed structure encapsulates a large number of adsorption sites and slows down the transfer rate of uranyl ions, resulting in a slight uranium adsorption capacity. Herein, PAO polymer chains are synthesized through the molecular coordination template method in the carboxylate covalent organic framework (COF) to obtain a PAO‐inserted COF adsorbent with open ion transport channels. After removing the protons, the COO− groups form in situ electric fields inside the 0.7 nm COF channel. This negatively‐charged framework reduces the electrostatic repulsion among uranium cations, thus realizing ultrahigh utilization of adsorption sites of PAO polymer (81.0%), far exceeding that of classical amidoxime‐based adsorbents (33.7%). After 10 days of contact with natural seawater, COF‐PAO achieved an average capacity of ≈12.26 mg‐U per g for uranium in Bohai (China), satisfying the uranium extraction standard (6.0 mg g−1). This work enumerates a method for the control of the spatial environment of polymer chains, and provides guidance for the design of subsequent high‐efficiency adsorbents.
Imaging Identifies Superior Inflammation Targeting of M1 Macrophages for Cryo‐Shocked Cell Pulmonary Drug Delivery to Treat Acute Lung Injury
Authors: Wang Xinyu , Liu Yuhang , Fan Yeli , Yan Junjie , Yan Ge , Liu Qingfeng , Xu Qian , Wang Lizhen , Pan Donghui , Xu Yuping , Chen Chongyang , Chen Yu , Yang Min 
Published: August 2024

AbstractIn the realm of combating acute lung injury (ALI) induced by a myriad of triggers including sepsis, pneumonia, aspiration, trauma, and pancreatitis, macrophages emerge as crucial players. However, traditional treatments such as systemic administration of glucocorticoids come with the baggage of severe side effects, curtailing their utility. Enter an innovative solution: a biomimetic drug delivery system fashioned from cryo‐shocked macrophages, tailored for pulmonary drug delivery. Positron emission tomography (PET) imaging has shed light on the remarkable targeting abilities of live M1 macrophages, showcasing their unparalleled efficacy in homing in on local inflammatory foci when contrasted with naive, M1, and M2 macrophages. Building upon this foundation, liquid nitrogen‐treated (LNT) M1 macrophages are developed, engineered to preserve their inflammation‐targeting prowess while sidestepping the release of pro‐inflammatory cytokines. This breakthrough allows for the delivery of glucocorticoids directly to inflamed lung tissues, efficiently quelling inflammation and mitigating pulmonary edema while drastically reducing systemic drug exposure. Inspired by the effectiveness of live M1 macrophages, the potential of glucocorticoid‐loaded LNT M1 macrophages are harnessed, utilizing them as a stealthy “Trojan horse” in the battle against pneumonia‐induced ALI. This innovative approach holds promise as a safe and potent treatment avenue for acute lung injury.
Stiffness and Interface Engineered Soft Electronics with Large‐Scale Robust Deformability
Authors: Liu Xiangye , Wang Qiangzheng , Zhou Sufeng , Feng Shiwei , Wei Yulin , Bu Fan , Wang Kai , Wang John , Zhang Biao , Guan Cao 
Published: August 2024

AbstractSkin‐like stretchable electronics emerge as promising human–machine interfaces but are challenged by the paradox between superior electronic property and reliable mechanical deformability. Here, a general strategy is reported for establishing robust large‐scale deformable electronics by effectively isolating strains and strengthening interfaces. A copolymer substrate is designed to consist of mosaic stiff and elastic areas with nearly four orders of magnitudes modulus contrast and cross‐linked interfaces. Electronic functional devices and stretchable liquid metal (LM) interconnects are conformally attached at the stiff and elastic areas, respectively, through hydrogen bonds. As a result, functional devices are completely isolated from strains, and resistances of LM conductors change by less than one time when the substrate is deformed by up to 550%. By this strategy, solar cells, wireless charging antenna, supercapacitors, and light‐emitting diodes are integrated into a self‐powered electronic skin that can laminate on the human body and exhibit stable performances during repeated multimode deformations, demonstrating an efficient path for realizing highly deformable energy autonomous soft electronics.
Biomimetic Nanomodulators With Synergism of Photothermal Therapy and Vessel Normalization for Boosting Potent Anticancer Immunity
Authors: Lan Jinshuai , Zeng Ruifeng , Li Zhe , Yang Xuguang , Liu Li , Chen Lixia , Sun Liyan , Shen Yi , Zhang Tong , Ding Yue 
Published: August 2024

AbstractCombination therapy using photothermal therapy (PTT) and immunotherapy is one of the most promising approaches for eliciting host immune responses to ablate tumors. However, its therapeutic efficacy is limited due to inefficient immune cell infiltration and cellular immune responses. In this study, a biomimetic immunostimulatory nanomodulator, Tm@PDA‐GA (4T1 membrane@polydopamine‐gambogic acid), with homologous targeting is developed. The 4T1 membrane (Tm) coating reduced immunogenicity and facilitated uptake of Tm@PDA‐GA by tumor cells. Polydopamine (PDA) as a drug carrier can induce PTT under near‐infrared ray (NIR) irradiation and immunogenic cell death (ICD) to activate dendritic cells (DCs). Moreover, Tm@PDA‐GA on‐demand released gambogic acid (GA) in an acidic tumor microenvironment, inhibiting the expression of heat shock proteins (HSPs) for synergetic chemo‐photothermal anti‐tumor activity and increasing the ICD of 4T1 cells. More importantly, GA can normalize the vessels via HIF‐1α and VEGF inhibition to enhance immune infiltration and alleviate hypoxia stress. Thus, Tm@PDA‐GA induced ICD, activated DCs, stimulated cytotoxic T cells, and suppressed Tregs. Moreover, Tm@PDA‐GA is combined with anti‐PD‐L1 to further augment the tumor immune response and effectively suppress tumor growth and lung metastasis. In conclusion, biomaterial‐mediated PTT combined with vessel normalization is a promising strategy for effective immunotherapy of triple‐negative breast cancer (TNBC).
Anisotropic Superprotonic Conduction in a Layered Single‐Component Hydrogen‐Bonded Organic Framework with Multiple In‐Plane Open Channels
Authors: Wang Zhiwei , Yang Lijuan , Chen Qian , Liu Peiyuan , Yang Zhiwei , Li Hai , Huang Xiao , Huang Wei 
Published: August 2024

AbstractHydrogen‐bonded organic frameworks (HOFs) are promising proton conductive materials because of their inherent and abundant hydrogen‐bonding sites. However, most superprotonic‐conductive HOFs are constructed from multiple components to enable favorable framework architectures and structural integrity. In this contribution, layered HOF‐TPB‐A3 with a single component is synthesized and exfoliated. The exfoliated nanoplates exhibited anisotropic superprotonic conduction, with in‐plane proton conductivities reaching 1.34 × 10−2 S cm−1 at 296 K and 98% relative humidity (RH). This outperforms the previously reported single‐component HOFs and is comparable with the state‐of‐the‐art multiple‐component HOFs. The high and anisotropic proton conductive properties can be attributed to the efficient proton transport along multiple open channels parallel to their basal planes. Moreover, an all‐solid‐state (ASS) proton rectifier device is demonstrated by combining HOF‐TPB‐A3 and a hydroxide ion‐conducting layered double hydroxide (LDH). This work suggests that single‐component HOFs with multiple open channels offer more opportunities as versatile platforms for proton conductors, making them promising candidates for conducting media in protonic devices.
Plant‐Derived Extracellular Vesicles as Potential Emerging Tools for Cancer Therapeutics
Authors: Ding Lin , Chang Chih‐Jung , Liang Min‐Li , Dong Kang‐Mei , Li Fu‐Rong 
Published: August 2024

AbstractExtracellular vesicles (EVs) are membranous structures secreted by cells that play important roles in intercellular communication and material transport. Due to its excellent biocompatibility, lipophilicity, and homing properties, EVs have been used as a new generation of drug delivery systems for the diagnosis and treatment of tumors. Despite the potential clinical benefits of animal‐derived extracellular vesicles (AEVs), their large‐scale production remains sluggish due to the exorbitant cost of cell culture, challenging quality control measures, and limited production capabilities. This constraint significantly hinders their widespread clinical application. Plant‐derived extracellular vesicles (PEVs) share similar functionalities with AEVs, yet they hold several advantages including a wide variety of source materials, cost‐effectiveness, ease of preparation, enhanced safety, more stable physicochemical properties, and notable efficacy. These merits position PEVs as promising contenders with broad potential in the biomedical sector. This review will elucidate the advantages of PEVs, delineating their therapeutic mechanisms in cancer treatment, and explore the prospective applications of engineered PEVs as targeted delivery nano‐system for drugs, microRNAs, small interfering RNAs, and beyond. The aim is to heighten researchers’ focus on PEVs and expedite the progression from fundamental research to the transformation of groundbreaking discoveries.
Non‐Electronic Activation of Anthracenes Using Steric Repulsion of the 9‐Substituent with Chloro Groups at the peri‐Positions
Authors: Indah Reza Annisa , Iwai Kento , Nishiwaki Nagatoshi 
Published: August 2024

AbstractWe investigated how the introduction of substituent at the 9‐ or 10‐position of the 1,8‐dichloroanthracene framework affects the horizontal and vertical distortions of the anthracene rings. The 9‐substituted anthracenes showed higher distortions than their 10‐substituted counterparts due to the steric repulsion with two chloro groups at the peri‐positions. The distortion of anthracene framework affected their reactivity. Indeed, 9‐substituted anthracenes exhibited higher reactivity to undergo the Diels–Alder reaction with maleic anhydride, which was a result of non‐electronic activation.
Homochiral Covalent Organic Frameworks with Superhelical Nanostructures Enable Efficient Chirality‐Induced Spin Selectivity
Authors: Hou Bang , Wang Kaixuan , Jiang Chao , Guo Yu , Zhang Xiaofeng , Liu Yan , Cui Yong 
Published: August 2024

AbstractDespite significant advancements in fabricating covalent organic frameworks (COFs) with diverse morphologies, creating COFs with superhelical nanostructures remains challenging. We report here the controlled synthesis of homochiral superhelical COF nanofibers by manipulating pendent alkyl chain lengths in organic linkers. This approach yields homochiral 3D COFs 13‐OR with a 10‐fold interpenetrated diamondoid structure (R=H, Me, Et, nPr, nBu) from enantiopure 1,1′‐bi‐2‐naphthol (BINOL)‐based tetraaldehydes and tetraamine. COF‐13‐OEt exhibits macroscopic chirality as right‐handed and left‐handed superhelical fibers, whereas others adopt spherical or non‐helical morphologies. Time‐tracking shows a self‐assembly process from non‐helical strands to single‐stranded helical fibers and intertwined superhelices. Ethoxyl substituents, being of optimal size, balance solvophobic effects and intermolecular interactions, driving the formation of superhelical nanostructures, with handedness determined by BINOL chirality. The superhelical nature of these materials is evident in their chiral recognition and spin‐filter properties, showing significantly improved enantiodiscrimination in carbohydrate binding (up to six times higher enantioselectivity) and a remarkable chiral‐induced spin selectivity (CISS) effect with a 48–51 % spin polarization ratio, a feature absent in non‐helical analogs.
Bismuthenium Cations for the Transport of Chloride Anions via Pnictogen Bonding
Authors: Hunter Nathanael H. , Gabbaï François P. 
Published: August 2024

AbstractOur interest in the design of heavy pnictogen‐based Lewis acids for anion trafficking across biological membrane mimics has led us to investigate trivalent bismuthenium cations as chloride anion transporters. Here, we describe two chlorodiarylbismuthines, elaborated on a peri‐substituted naphthalene backbone and stabilized by an adjacent thio‐ or seleno‐ether functionality that engages the bismuth center in a Ch→Bi interaction (Ch=chalcogen). These new derivatives are stable in aqueous environment and readiliy transport chloride anions across the membrane of phospholipid‐based vesicles loaded with KCl. In addition to establishing the use of such motifs in anion transport, this investigation shows that the Lewis acidity, lipophilicity, and thus chloride transport properties depend on the nature of the chalcogen.
Asymmetrified Benzothiadiazole‐Based Solid Additives Enable All‐Polymer Solar Cells with Efficiency Over 19 %
Authors: Chen Tianqi , Zhong Yanyi , Duan Tainan , Tang Xian , Zhao Wenkai , Wang Jiaying , Lu Guanghao , Long Guankui , Zhang Jiangbin , Han Kai , Wan Xiangjian , Kan Bin , Chen Yongsheng 
Published: August 2024

AbstractDisordered polymer chain entanglements within all‐polymer blends limit the formation of optimal donor‐acceptor phase separation. Therefore, developing effective methods to regulate morphology evolution is crucial for achieving optimal morphological features in all‐polymer organic solar cells (APSCs). In this study, two isomers, 4,5‐difluorobenzo‐c‐1,2,5‐thiadiazole (SF‐1) and 5,6‐difluorobenzo‐c‐1,2,5‐thiadiazole (SF‐2), were designed as solid additives based on the widely‐used electron‐deficient benzothiadiazole unit in nonfullerene acceptors. The incorporation of SF‐1 or SF‐2 into PM6 : PY‐DT blend induces stronger molecular packing via molecular interaction, leading to the formation of continuous interpenetrated networks with suitable phase‐separation and vertical distribution. Furthermore, after treatment with SF‐1 and SF‐2, the exciton diffusion lengths for PY‐DT films are extended to over 40 nm, favoring exciton diffusion and charge transport. The asymmetrical SF‐2, characterized by an enhanced dipole moment, increases the power conversion efficiency (PCE) of PM6 : PY‐DT‐based device to 18.83 % due to stronger electrostatic interactions. Moreover, a ternary device strategy boosts the PCE of SF‐2‐treated APSC to over 19 %. This work not only demonstrates one of the best performances of APSCs but also offers an effective approach to manipulate the morphology of all‐polymer blends using rational‐designed solid additives.