bluuebunny/crossref_metadata_2025_split huggingface dataset:
Isolated panniculitis with vasculitis of the male breast suspicious for malignancy on CT and ultrasound: a case report and literature review
Authors: Yuan Wei-Hsin , Li Anna Fen-Yau , Hsu Hui-Chen , Chou Yi-Hong 
Published: October 2014

Abstract

Introduction
We report a case of a 54-year-old male patient with a hard, painful nodule within his right breast which was misdiagnosed preoperatively as breast cancer.

Case description
Preoperative work-up included physical examination, non-contrast chest computed tomography (CT), sonography, and sono-guided breast biopsy. Isolated breast panniculitis with vasculitis (BPWV), a rare disease, was diagnosed by histopathologic examination of tissue obtained from excisional biopsy.

Discussion and Evaluation
Subcutaneous panniculitis with or without vasculitis, a condition of nonsuppurative inflammatory process involving the subcutaneous fat layer of skin, is related to different causes. A palpable benign male breast lesion resembling a malignancy includes gynecomastia, panniculitis with or without vasculitis, fat necrosis, ruptured epidermal cyst, pseudoangiomatous stromal hyperplasia, subareolar abscess, intraductal papilloma, hematoma, and atypical fibroadenoma. To make an accurate preoperative diagnosis of a male breast mass, a physician has to carefully analyze various imaging findings. The cases of BPWV may present as an isolated breast lesion or as a component of a systemic disease. The diagnosis of the reported patient was compatible with an isolated BPWV because panniculitis and/or vasculitis were not present at other sites or organs at the time of diagnosis or during follow-up.

Conclusions
Excisional biopsy and clinical data can provide the correct diagnosis and determined the appropriate treatment strategy of a male BPWV.
Identification of chemokine receptors as potential modulators of endocrine resistance in oestrogen receptor–positive breast cancers
Authors: Ribas Ricardo , Ghazoui Zara , Gao Qiong , Pancholi Sunil , Rani Aradhana , Dunbier Anita , Dowsett Mitch , Martin Lesley-Ann 
Published: October 2014

Abstract
Introduction
Endocrine therapies target oestrogenic stimulation of breast cancer (BC) growth, but resistance remains problematic. Our aims in this study were (1) to identify genes most strongly associated with resistance to endocrine therapy by intersecting global gene transcription data from patients treated presurgically with the aromatase inhibitor anastrazole with those from MCF7 cells adapted to long-term oestrogen deprivation (LTED) (2) to assess the clinical value of selected genes in public clinical data sets and (3) to determine the impact of targeting these genes with novel agents.

Methods
Gene expression and Ki67 data were available from 69 postmenopausal women with oestrogen receptor–positive (ER+) early BC, at baseline and 2 weeks after anastrazole treatment, and from cell lines adapted to LTED. The functional consequences of target genes on proliferation, ER-mediated transcription and downstream cell signalling were assessed.

Results
By intersecting genes predictive of a poor change in Ki67 with those upregulated in LTED cells, we identified 32 genes strongly correlated with poor antiproliferative response that were associated with inflammation and/or immunity. In a panel of LTED cell lines, C-X-C chemokine receptor type 7 (CXCR7) and CXCR4 were upregulated compared to their wild types (wt), and CXCR7, but not CXCR4, was associated with reduced relapse-free survival in patients with ER+ BC. The CXCR4 small interfering RNA variant (siCXCR4) had no specific effect on the proliferation of wt-SUM44, wt-MCF7 and their LTED derivatives. In contrast, siCXCR7, as well as CCX733, a CXCR7 antagonist, specifically suppressed the proliferation of MCF7-LTED cells. siCXCR7 suppressed proteins associated with G1/S transition and inhibited ER transactivation in MCF7-LTED, but not wt-MCF7, by impeding association between ER and proline-, glutamic acid– and leucine-rich protein 1, an ER coactivator.

Conclusions
These data highlight CXCR7 as a potential therapeutic target warranting clinical investigation in endocrine-resistant BC.
Electrochemical Performance of LiFe0.97Sn0.03PO4/C Composites Synthesized by the High-temperature High-energy Ball Milling Method
Authors: Wang Juan , Shao Zhongbao , Ru Hongqiang 
Published: October 2014

Abstract
LiFePO4/C and LiFe0.97Sn0.03PO4/C composites were synthesized by a novel preparation method of high-temperature high-energy ball milling (HTHEBM). The composites were characterized by XRD, SEM, and electrochemical performance tests. The results indicate that the physical properties and electrochemical performance of the LiFe0.97Sn0.03PO4/C sample were greatly improved by the introduction of SnO2. The improved discharge capacities of the sample are 159 mA h g−1 at 0.1 C and 144 mA h g−1 at 5 C, and the capacity retention is 99% after 30 cycles, tested at 5 C.
Ambivalent anti-heroes and racist rednecks on basic cable: Post-race ideology and white masculinities on FX
Authors: Wayne Michael L. 
Published: October 2014

Abstract
This article explores the representations of white masculinities and the depiction of racism in anti-heroic narratives on the basic cable network FX in the United States. By juxtaposing the ambivalent racial sensibilities of a morally ambiguous white protagonist with the overt racism of stereotypical depictions of the white underclass, The Shield (2002–2008), Sons of Anarchy (2008–) and Justified (2010–) acknowledge the continuing existence of racial prejudice in American society while also supporting the dominant colour blind rhetoric that denies the continuing impact of structural racism. Although some scholars interpret the popularity of hyper-masculine anti-hero shows that speak to the notion of ‘masculinity-in-crisis’ as indicative of the declining benefits associated with white, male privilege, this analysis uses G. Harris’ notion of ‘postmasculinist television drama’ to argue that the consistent deployment of white masculinities in these FX programmes reinforce the post-race ideology associated with hegemonic whiteness by ‘othering’ problematic racial attitudes yet still allow white audiences to take ‘ironic’ pleasure from expressions of overt racism.
Sensitivity of field tests, serological and molecular techniques for Plum Pox Virus detection in various tissues
Authors: VIRŠČEK MARN Mojca , MAVRIČ  PLEŠKO Irena , ALTENBACH Denise , BITTERLIN Walter 
Published: October 2014

Sensitivity of field tests (AgriStrip and Immunochromato), DAS-ELISA, two step RT-PCR and real-time RT-PCR for Plum pox virus (PPV) detection was tested in various tissues of apricot, peach, plum and damson plum trees infected with isolates belonging to PPV-D, PPV-M or PPV-Rec, the three strains present in Slovenia. Flowers of apricot and plum in full bloom proved to be a very good source for detection of PPV. PPV could be detected with all tested techniques in symptomatic parts of leaves in May and with one exception even in the beginning of August, but it was not detected in asymptomatic leaves using field tests, DAS-ELISA and partly also molecular techniques. PPV was detected only in some of the samples of asymptomatic parts of the leaves with symptoms and of stalks by field tests and DAS-ELISA. Infections were not detected in buds in August using field tests or DAS-ELISA. Field tests are useful for confirmation of the PPV infection in symptomatic leaves, but in tissues without symptoms DAS-ELISA should be combined or replaced by molecular techniques.
Quality of cv. 'Gala Brookfield' and ‘Fuji Kiku 8' apples grown under and outside hail net
Authors: GERMŠEK Blaž , UNUK Tatjana 
Published: October 2014

Anti-hail nets for the production of apples has become a normally action for a new or update an old apple orchard. In 2007 and 2008, the development of quality and maturity parameters of cv. 'Gala Brookfield' and ‘Fuji Kiku 8' apples grafted on M9 were studied in the Fruit growing centre Maribor-Gačnik as a factor of being grown under a blackhail net. The results showed that when grown under the black hail net fruit of both cultivars reach a higher mean mass, lower soluble solids content (0.6 to 1 ° Brix), and lower starch index, while no effect of the black hail net was detected on fruit flesh firmness and yield.
The effect of gamma radiation on seed germination of barley (Hordeum vulgare L.)
Authors: ROZMAN Ludvik 
Published: October 2014

The aim of the study was to determine the effect of gamma radiation on barley (Hordeum vulgare L.) seed germination and changes of seed viability associated with aging. The seed samples of the variety 'Astor' were irradiated at the Jožef Štefan Institute, in the Reactor Centre at Podgorica near Ljubljana, in 2006. The samples were irradiated with three different doses: 0.1, 0.2 and 0.4 kGy. After the irradiation, the seeds were stored in a refrigerator at 4 °C. The percentage of seed germination was tested each year after irradiation until 2014, except in the second and the third year. The experiments were based on the Latin square design with 4 replications of each treatment, and were conducted in a greenhouse under controlled temperature at 20 °C. In all years, the samples irradiated with the highest dose (0.4 kGy) exhibited a significantly lower percentage of germination. The germination rate of the samples irradiated with 0.2 and 0.4 kGy decreased significantly with aging, when compared to the control and the samples irradiated with 0.1 kGy. In all years of testing, the percentage of germination of seeds irradiated with 0.1 kGy did not differ from the control, and in the fifth year after irradiation, it was even significantly higher than the control.
Applying Model-based Software Product Line Testing Approaches to the Automation Engineering Domain
Authors: Lochau Malte , Bürdek Johannes , Lity Sascha , Hagner Matthias , Legat Christoph , Goltz Ursula , Schürr Andy 
Published: October 2014

Abstract
The software constitutes a major part of nowadays automation systems being responsible for conducting complex control tasks. Machines
and plants are often unique in some industrial branches; hence, they become mechatronic products configured individually. The inherent
software variability of those highly-configurable systems makes efficient, yet accurate quality assurance a challenging task. This
article presents a comprehensive approach for applying model-based software product line testing techniques to the automation
engineering domain. Existing approaches for variability modeling are adapted to domain specific modeling languages to allow for
variability-aware test case generation and execution. The implementation of the approach is evaluated by means of a sample automation
system product line.
Interface Behavior Modeling for Automatic Verification of Industrial Automation Systems' Functional Conformance
Authors: Legat Christoph , Mund Jakob , Campetelli Alarico , Hackenberg Georg , Folmer Jens , Schütz Daniel , Broy Manfred , Vogel-Heuser Birgit 
Published: October 2014

Abstract
To facilitate engineering and evolution of automation systems, ensuring the correctness of the design models is an important topic. Industrial automation systems are composed of various heterogeneous elements designed by different disciplines such as mechanical, electrical/electronic and software engineering. In this contribution, an approach for modeling industrial automation systems is presented which is based on interface behavior modeling of design artifacts and which supports automatic verification of their functional conformance while considering information from various disciplines.
Genetic Studies in Sunflower Broomrape
Authors: Rodríguez-Ojeda María I. , Pineda-Martos Rocío , Alonso Luis C. , Fernández-Martínez José M. , Velasco Leonardo , Fernández-Escobar Juan , Pérez-Vich Begoña 
Published: October 2014

AbstractMuch research has been conducted to identify sources of genetic resistance to sunflower broomrape (
Penalized Multimarkervs.Single-Marker Regression Methods for Genome-Wide Association Studies of Quantitative Traits
Authors: Yi Hui , Breheny Patrick , Imam Netsanet , Liu Yongmei , Hoeschele Ina 
Published: October 2014

AbstractThe data from genome-wide association studies (GWAS) in humans are still predominantly analyzed using single-marker association methods. As an alternative to single-marker analysis (SMA), all or subsets of markers can be tested simultaneously. This approach requires a form of penalized regression (PR) as the number of SNPs is much larger than the sample size. Here we review PR methods in the context of GWAS, extend them to perform penalty parameter and SNP selection by false discovery rate (FDR) control, and assess their performance in comparison with SMA. PR methods were compared with SMA, using realistically simulated GWAS data with a continuous phenotype and real data. Based on these comparisons our analytic FDR criterion may currently be the best approach to SNP selection using PR for GWAS. We found that PR with FDR control provides substantially more power than SMA with genome-wide type-I error control but somewhat less power than SMA with Benjamini–Hochberg FDR control (SMA-BH). PR with FDR-based penalty parameter selection controlled the FDR somewhat conservatively while SMA-BH may not achieve FDR control in all situations. Differences among PR methods seem quite small when the focus is on SNP selection with FDR control. Incorporating linkage disequilibrium into the penalization by adapting penalties developed for covariates measured on graphs can improve power but also generate more false positives or wider regions for follow-up. We recommend the elastic net with a mixing weight for the Lasso penalty near 0.5 as the best method.
Effects of Reclaimed Waters on Spectral Properties and Leaf Traits of Citrus Orchards
Authors: Contreras S. , Pérez‐Cutillas P. , Santoni C.S. , Romero‐Trigueros C. , Pedrero F. , Alarcón J. J. 
Published: October 2014

ABSTRACT: Effects resulting from the use of reclaimed waters on mandarins and grapefruits are evaluated by measuring the spectral responses of their canopies and the anatomy and the chlorophyll content of their leaves against control trees irrigated with waters provided by an interbasin transfer. Spectral responses from the red (R) and near‐infrared (NIR) wavelength bands, and its normalized ratio (NDVI), were acquired from a hyperspatial flight conducted after a low‐moderate exposition to reclaimed waters. Chlorophyll and leaf and palisade/spongy ratio thicknesses were analyzed after a moderate‐high exposition. Significant differences between controls and treatments were detected in mandarins in R and leaf chlorophyll, but not in grapefruits, likely because of their higher tolerance to saline waters. Reused waters did not affect either NIR–NDVI or anatomy traits. Hyperspatial sensing techniques are suitable for detecting chlorophyll dynamics, but NIR information and related vegetation indices may mask the detection of periods of saline stress in citrus orchards.
Early Treatment Withdrawal from Evidence-Based Psychotherapy for PTSD: Telemedicine and in-Person Parameters
Authors: Hernandez-Tejada Melba A. , Zoller James S. , Ruggiero Kenneth J. , Kazley Abby Swanson , Acierno Ron 
Published: October 2014

Objective: To determine differences in reported barriers to treatment completion associated with telemedicine vs. in-person delivery of evidence-based treatment for PTSD in combat veterans. Method: The present study was derived from two ongoing randomized controlled trials (RCTs) comparing in-person vs. telemedicine delivery of exposure therapy for PTSD. A onetime telephone assessment of participants who dropped out from the treatment phase of these two studies was conducted, with measures focusing on reported reasons for dropout, and perceived comfort and efficacy of the treatment modality. Dichotomous data were analyzed via chi-square and logistic regression; continuous data via ANOVA. Results: Forty-seven of 69 total dropouts participated. There was no difference in rate of dropout between modalities. A greater proportion of participants receiving in-person exposure therapy reported difficulties with logistical aspects of care (e.g., parking), whereas a greater proportion of participants receiving telemedicine therapy reported difficulty tolerating certain stressful aspects of treatment; however, those receiving telemedicine delivered treatment completed more sessions before dropping out. Participants in both conditions reported that they liked and were confident in their therapist Conclusions: Dropout reasons varied according to type of treatment delivery. Recommendations for future research are given in terms of modification of treatment protocol according to delivery modality.
Effects of approach and injection volume on diffusion of mepivacaine hydrochloride during local analgesia of the deep branch of the lateral plantar nerve in horses
Authors: Claunch Kevin M. , Eggleston Randy B. , Baxter Gary M. 
Published: October 2014

Abstract
Objective—To compare the effects of 2 approaches and 2 injection volumes on diffusion of mepivacaine hydrochloride for local analgesia of the deep branch of the lateral plantar nerve (DBLPN) in horses.
Design—Experimental study.
Animals—16 adult horses.
Procedures—Either 2 mL (low volume) or 8 mL (high volume) of mepivacaine hydrochloride-iohexol (50:50 mixture) was injected by means of 1 of 2 techniques to produce analgesia of the DBLPN. For technique 1, the needle was inserted 15 mm distal to the head of the fourth metatarsal bone and directed perpendicular to the limb. For technique 2, the needle was inserted 20 mm distal to the head of the fourth metatarsal bone and was directed in a proximodorsal direction. Lateromedial radiographs were obtained before and 5, 15, 30, and 60 minutes after injection. Radiographs were evaluated to determine the proximal and distal extent of diffusion of the contrast solution and presumably anesthetic agent and whether contrast agent appeared to be present in the tarsal sheath or tarsometatarsal joint.
Results—A high degree of variability in contrast solution diffusion was noted among injections. High-volume injections diffused significantly further proximally and distally than did low-volume injections. Contrast agent was documented within the tarsal sheath in 5 of 32 (16%) injections and within the tarsometatarsal joint in 2 of 32 (6%) injections. No significant difference was found for risk of inadvertent tarsal sheath or tarsometatarsal joint injection between the 2 techniques or the 2 volumes of anesthetic used. Mepivacaine diffused significantly further distally with technique 1 than with technique 2 but diffused significantly further proximally with technique 2 than with technique 1. For both techniques, diffusion in the distal but not the proximal direction significantly increased over time.
Conclusions and Clinical Relevance—Results indicated that the proximal and distal diffusion of the mepivacaine-iohexol solution was quite variable following either DBLPN nerve block technique.
Welche Faktoren bestimmen den Erfolg der Moderholzverjüngung im Fichtenurwald Scatlè?
Authors: Stroheker Sophie , Martin Salome , Sieber Thomas N. , Bugmann Harald , Weiss Marc 
Published: October 2014

Which factors determine regeneration on nurse logs in the Scatlè virgin forest?
Harsh environmental conditions in subalpine forests render Norway spruce regeneration difficult, limiting germination and establishment to a few microsites such as decaying logs. In 2002, spruce regeneration was studied on coarse woody debris (CWD) in the Swiss virgin forest Scatlè. In 2012, regeneration status and the factors characterizing environmental conditions were re-assessed. The statistical model that had been parameterized with the 2002 data also performed well with the explanatory variables measured in 2012, indicating that regeneration on CWD is a non-random, complex process resulting from the interaction of several ecological factors. A 5.5-fold increase of regeneration density was observed over the past ten years, which is most likely attributable to a higher abundance of suitable microsites on CWD: 1) an increase of moderately and strongly decayed wood, 2) average sunshine duration in June of 50 to 120 minutes per day, 3) a decrease of the plot-to-ground distance with little competition by the surrounding ground vegetation, 4) an increase of the thickness of moss cover. The mast years of 2009 and 2011 certainly were influential for the increase of regeneration density. Establishment of regeneration may start as early as six years after tree death, but logs older than 23 years were most suitable. Natural regeneration on rotten wood thus is a slow and long-lasting process, and the sustainability of regeneration requires a continuous supply of dead wood of different decay stages. Besides the important role of dead and dying trees for spruce regeneration, we also found an important role of CWD for biodiversity, as fifteen species of decay fungi were detected, two of them having the status of endangered species.
Looking through drumlins: testing the application of ground-penetrating rada
Authors: Spagnolo Matteo , King Edward C. , Ashmore David W. , Rea Brice R. , Ely Jeremy C. , Clark Chris D. 
Published: October 2014

AbstractGround-penetrating radar (GPR) is becoming a commonly applied technique in geomorphology. However, its use in the study of subglacial bedforms has yet to be fully explored and exploited. This paper presents the results of a GPR feasibility study conducted on a drumlinized terrain in Cumbria, UK, where five drumlins were investigated using multiple radar antenna frequencies. The site was selected for the presence of nearby bedrock outcrops, suggesting a shallow drumlinized diamict–bedrock contact and a permeable lithology. Despite the clayey sediment and unfavourable weather conditions, a considerable penetration depth of ~12 m was achieved when using a 50 MHz antenna, with a separation of 1 m, trace spacing of 1 m and 128-fold vertical stack. Results indicate that the drumlinized diamict is in direct erosional contact with the bedrock. While the internal drumlin geometry is generally chaotic on the stoss side, evidence of layering dipping downflow at an angle greater than the drumlin surface profile was found on the lee side. The inter-drumlin areas comprise ~4 m of infill sediment that masks part of the original drumlin profile. Overall, this study indicates that GPR can be deployed successfully in the study of glacial bedform sedimentary architecture.
A simple, inexpensive, and field‐relevant microcosm tidal simulator for use in marsh macrophyte studies
Authors: MacTavish Rachel M. , Cohen Risa A. 
Published: October 2014

• Premise of the study: A microcosm unit with tidal simulation was developed to address the challenge of maintaining ecologically relevant tidal regimes while performing controlled greenhouse experiments on smooth cordgrass, Spartina alterniflora.• Methods and Results: We designed a simple, inexpensive, easily replicated microcosm unit with tidal simulation and tested whether S. alterniflora growth in microcosms with tidal simulation was similar to that of tidally influenced plants in the field on Sapelo Island, Georgia. After three months of exposure to either natural or simulated tidal treatment, plants in microcosms receiving tidal simulation had similar stem density, height, and above‐ and belowground biomass to plants in field plots.• Conclusions: The tidal simulator developed may provide an inexpensive, effective method for conducting studies on S. alterniflora and other tidally influenced plants in controlled settings to be used not only to complement field studies, but also in locations without coastal access.