bluuebunny/crossref_metadata_2025_split huggingface dataset:
« Le doudou de ma fille, ça pue tellement bon ! »
Authors: Wathelet Olivier 
Published: April 2013

Le statut épistémique des odeurs occupe une place à part dans la littérature scientifique, en particulier en psychologie cognitive et au sein de l’anthropologie des sens. À partir d’une enquête ethnographique conduite en France et en Belgique francophone, nous montrons les limites d’une conception dominante de ces travaux qui consiste à trier les expériences olfactives dans le cadre d’un clivage hédonique, bonnes et mauvaises odeurs s’opposant d’un point de vue affectif, cognitif et normatif. Prenant appui sur une démarche d’ethnographie cognitive des perceptions consistant à étudier les odeurs en tant que résultat d’un processus de jugement dont on peut étudier le déploiement en tant qu’activité mentale située, nous montrons dans un premier temps la place qu’occupent les « mauvaises odeurs » corporelles dans l’intimité de nos informateurs. Puis nous présentons les odeurs oxymorons qui sont jugées à la fois bonnes et mauvaises. Ces deux cas illustrent les limites d’une analyse des odeurs en termes de clivage hédonique. Au-delà de cette question spécifique, nous proposons une analyse ethnographique des jugements cognitifs au coeur de l’intime comme cadre pour le développement de l’anthropologie des sens, et un rapprochement vis-à-vis des travaux de la psychologie cognitive dans ce domaine.
Integrative therapy of traditional Chinese medicine and conventional medicine in the treatment of lupus nephritis from a single‐center experience
Authors: Liu Ruihua , Yang Xiao , Yu Jianwen , Wen Qiong , Yu Xueqing , Chen Wei 
Published: July 2024

AbstractLupus nephritis (LN) is the most common complication of systemic lupus erythematosus and the leading cause of mortality. The complex pathogenesis and various clinical manifestations of this disease increase the difficulty of the treatments. The current treatments with Western medicine including glucocorticoids, mycophenolate mofetil and other immunosuppressants, and biological agents have greatly improved the patients' survival. However, frequent recurrence occurred and LN remained an important cause of end stage renal disease. The increasing adverse effects with the prolongation of treatment also restrained the efficacy of Western medicine. Increasing evidence has demonstrated the therapeutic efficacy of traditional Chinese medicine (TCM) which provides a theoretical basis for the integrative therapy of TCM and Western medicine for LN. We previously established a unique comprehensive treatment strategy for LN with the combination of TCM and Western medicine based on the TCM theory and achieved good clinical efficacy. This review will summarize the single‐center experience that integrative therapy of TCM, represented by Lupus Recipe and artesunate, and Western medicine for LN treatment, and elucidate the potential mechanism, with the purpose to provide reliable evidence for developing more effective personalized treatment strategies in the future.
An externally validated prognostic model for critically ill patients with traumatic brain injury
Authors: Lu Yan , Zhang Qiaohong , Jiang Jinwen , Zhang Yongjun 
Published: July 2024

AbstractObjectivePatients with traumatic brain injury (TBI) who are admitted to the intensive care unit often exhibit critical conditions; thus, early prediction of in‐hospital mortality is crucial. In this study, we aimed to develop a reliable and easily promotable model for predicting the in‐hospital mortality of critically ill patients with TBI using easily accessible indicators and validate the model using external data.MethodsPatient data from the Medical Information Mart for Intensive Care‐IV 2.2 database were used as training and internal validation sets to establish and internally validate the prognostic model. Data from the Affiliated Dongyang Hospital of Wenzhou Medical University were used for external validation. The Boruta algorithm was used for the initial feature selection, followed by univariate and multivariate logistic regression analyses to identify the final independent predictors. The predictive performance was evaluated using a receiver operating characteristic curve, calibration curve, clinical practicality decision curve analysis, and clinical impact curve.ResultsThis study included 3225 patients (training set: 2042; internal validation set: 874; and external validation set: 309). Ten variables were selected for inclusion in the nomogram model: age, mechanical ventilation usage, vasoactive agent usage, intracerebral hemorrhage, temperature, respiration rate, white blood cell count, platelet count, red blood cell distribution width, and glucose. The nomogram demonstrated good predictive performance in both the internal and external validation sets.InterpretationWe developed an externally validated nomogram that exhibited good discrimination, calibration, and clinical utility for predicting in‐hospital mortality in critically ill patients with TBI.
Assessing Patient Values and Preferences to Inform the 2023 American College of Rheumatology/American College of Chest Physicians Interstitial Lung Disease Guidelines
Authors: Mirza Reza D. , Bolster Marcy B. , Johnson Sindhu R. , Allen Aberdeen , Bernstein Elana J. , Chung Jonathan H. , Danoff Sonye K. , Falardeau Catherine , Guyatt Gordon , Ivlev Ilya , Khanna Dinesh , Nesbitt Kiana T. , Turner Amy , Uhl Stacey , George Michael D. 
Published: July 2024

ObjectivePatient engagement is critical to clinical practice guideline (CPG) development. This work presents our approach to ascertaining patients’ values and preferences to inform the American College of Rheumatology guidelines for screening, monitoring, and treatment of interstitial lung disease (ILD) in people with systemic autoimmune rheumatic diseases (SARDs).MethodsWe conducted a cross‐sectional qualitative study of a purposefully sampled Patient Panel using a modified content analytic approach. The study team reviewed text transcripts from the Patient Panel discussion to identify themes and develop a clustered thematic schema.ResultsTwenty‐one patients (75% women) participated, with a mean age of 53 years (range 33–73). Patients had one or more SARDs: systemic sclerosis (38%), Sjögren disease (38%), idiopathic inflammatory myopathy (33%), rheumatoid arthritis (24%), and mixed connective tissue disease (10%). We identified 10 themes in 4 thematic clusters: communication, screening and monitoring, treatment goals, and treatment adverse effects. Patients prioritized recognizing ILD symptoms, importance of ILD screening and close monitoring, goals of survival and improving quality of life, and willingness to accept treatment risks provided that there is close communication with providers. Patient representatives shared patients’ priorities and insight at the Voting Panel meeting, influencing multiple guideline recommendations.ConclusionPatient engagement fosters a holistic approach to CPG development, leading to recommendations aiming for the best clinical outcomes while prioritizing outcomes important for patients. The patient‐identified themes played a critical role in ILD guideline development and provide core elements for shared decision‐making as clinicians make management and therapeutic decisions with patients with SARD‐associated ILD.image
Built‐In Trimodal Molecular Interaction Effect Enables Interface‐Compatible and Temperature‐Tolerance Aqueous Zinc Batteries
Authors: Chen Qiuting , Ouyang Kefeng , Wang Yanyi , Chen Minfeng , Mi Hongwei , Chen Jizhang , He Chuanxin , Li Hui , Ma Dingtao , Zhang Peixin 
Published: July 2024

AbstractAqueous zinc‐ion batteries compatible with a wide temperature range and long cycle lifespan show great application prospects but are greatly limited by the unstable electrode‐electrolyte interfaces and mismatched electrolytes. This report presents the pathway of succinamic acid (SA) additive‐induced built‐in trimodal molecular interaction for constructing sustainable aqueous zinc batteries. As confirmed, such trimodal molecular interaction falls into the following patterns: the binding state of the H─F bond between SA and polyvinylidene fluoride (PVDF) binder, the micellar aggregation state in aqueous electrolyte, and the spontaneous adsorption state at Zn anode–electrolyte interface. Benefiting from the above synergistic effect, the Zn electrode shows a highly reversible deposition/stripping behavior over the wide temperature range (−10–50 °C) when paired with the optimized electrolyte. Specially, an impressive 3530 h‐cycle lifespan of the Zn symmetrical cell is achieved at the conditions of 1 mA cm−2 and 1 mAh cm−2. Beyond that, significantly improved storage capability and cycle performance are demonstrated in both aqueous Zn‐MnO2 and Zn‐I2 batteries. Given the good balance between the working temperature range, ionic conductivity, and Zn2+ transfer number of this trace molecule‐mediated electrolyte, this design paradigm provides new insights into developing advanced aqueous batteries, including but not limited to zinc‐based systems.
Heterogeneous‐Structured Refractory High‐Entropy Alloys: A Review of State‐of‐the‐Art Developments and Trends
Authors: Xu Dingfeng , Wang Xiaodi , Lu Yiping 
Published: July 2024

AbstractRefractory high‐entropy alloys (RHEAs) inspire the development of novel high‐temperature structural materials due to their outstanding resistance to softening and phase stability at elevated temperatures. However, they struggle to simultaneously achieve high‐temperature strength and room‐temperature ductility, while exhibiting insufficient room‐temperature strain hardening capability. Heterogeneous structure strengthening possesses a unique plastic self‐coordinated ability, which can effectively maintain strain hardening rate to achieve an excellent combination of strength and ductility. Benefiting from slow atomic diffusion, severe lattice distortion, and broad compositional design space, RHEAs with heterogeneous structures can be prepared from both chemical composition and interface structure perspectives. Chemical composition heterogeneity primarily focuses on fluctuations of alloying elements at the nanoscale, along with the formation of heterogeneous precipitates and unique lamellar eutectic structures. While, interface structure heterogeneity manifests in the activation of phase transformation and twin boundaries within grains, along with the formation of grains of vastly different sizes. The trend in RHEAs development is toward structural‐functional integration. Heterogeneous structures can also optimize functional properties, such as irradiation resistance, biomedical properties, and high‐temperature softening resistance of RHEAs. Finally, a brief outlook is provided on the future development direction of heterogeneous structure RHEAs.
Sliding Memristor in Parallel‐Stacked Hexagonal Boron Nitride
Authors: Du Shuang , Yang Wenqi , Gao Huiying , Dong Weikang , Xu Boyu , Watanabe Kenji , Taniguchi Takashi , Zhao Jing , Zheng Fawei , Zhou Jiadong , Zheng Shoujun 
Published: July 2024

AbstractSliding ferroelectricity in 2D materials, arising from interlayer sliding‐induced interlayer hybridization and charge redistribution at the van der Waals interface, offers a means to manipulate spontaneous polarization at the atomic scale through various methods such as stacking order, interfacial contact, and electric field. However, the practical application of extending 2D sliding ferroelectricity remains challenging due to the contentious mechanisms and the complex device structures required for ferroelectric switching. Here, a sliding memristor based on a graphene/parallel‐stacked hexagonal boron nitride/graphene tunneling device, featuring a stable memristive hysteresis induced by interfacial polarizations and barrier height modulations, is presented. As the tunneling current density increases, the memristive window broadens, achieving an on/off ratio of ≈103 and 2 order decrease of the trigger current density, attributed to the interlayer migration of positively charged boron ions and the formation of conductive filaments, as supported by the theoretical calculations. The findings open a path for exploring the sliding memristor via a tunneling device and bridge the gap between sliding ferroelectricity and memory applications.
Balancing Pd–H Interactions: Thiolate‐Protected Palladium Nanoclusters for Robust and Rapid Hydrogen Gas Sensing
Authors: Chen Zhuo , Yuan Peng , Chen Cailing , Wang Xinhuilan , Wang Jinrong , Jia Jiaqi , Davaasuren Bambar , Lai Zhiping , Khashab Niveen M. , Huang Kuo‐Wei , Bakr Osman M. , Yin Jun , Salama Khaled N. 
Published: July 2024

AbstractThe transition toward hydrogen gas (H2) as an eco‐friendly and renewable energy source necessitates advanced safety technologies, particularly robust sensors for H2 leak detection and concentration monitoring. Although palladium (Pd)‐based materials are preferred for their strong H2 affinity, intense palladium–hydrogen (Pd–H) interactions lead to phase transitions to palladium hydride (PdHx), compromising sensors’ durability and detection speeds after multiple uses. In response, this study introduces a high‐performance H2 sensor designed from thiolate‐protected Pd nanoclusters (Pd8SR16), which leverages the synergistic effect between the metal and protective ligands to form an intermediate palladium–hydrogen–sulfur (Pd–H–S) state during H2 adsorption. Striking a balance, it preserves Pd–H binding affinity while preventing excessive interaction, thus lowering the energy required for H2 desorption. The dynamic adsorption‐dissociation‐recombination‐desorption process is efficiently and highly reversible with Pd8SR16, ensuring robust and rapid H2 sensing at parts per million (ppm). The Pd8SR16‐based sensor demonstrates exceptional stability (50 cycles; 0.11% standard deviation in response), prompt response/recovery (t90 = 0.95 s/6 s), low limit of detection (LoD, 1 ppm), and ambient temperature operability, ranking it among the most sensitive Pd‐based H2 sensors. Furthermore, a multifunctional prototype demonstrates the practicality of real‐world gas sensing using ligand‐protected metal nanoclusters.
Inhibiting Interfacial Nonradiative Recombination in Inverted Perovskite Solar Cells with a Multifunctional Molecule
Authors: Wu Jiaxin , Zhu Rui , Li Guixiang , Zhang Zuhong , Pascual Jorge , Wu Hongzhuo , Aldamasy Mahmoud H. , Wang Luyao , Su Zhenhuang , Turren‐Cruz Silver‐Hamill , Roy Rajarshi , Alharthi Fahad A , Alsalme Ali , Zhang Junhan , Gao Xingyu , Saliba Michael , Abate Antonio , Li Meng 
Published: July 2024

AbstractInterface‐induced nonradiative recombination losses at the perovskite/electron transport layer (ETL) are an impediment to improving the efficiency and stability of inverted (p‐i‐n) perovskite solar cells (PSCs). Tridecafluorohexane‐1‐sulfonic acid potassium (TFHSP) is employed as a multifunctional dipole molecule to modify the perovskite surface. The solid coordination and hydrogen bonding efficiently passivate the surface defects, thereby reducing nonradiative recombination. The induced positive dipole layer between the perovskite and ETLs improves the energy band alignment, enhancing interface charge extraction. Additionally, the strong interaction between TFHSP and the perovskite stabilizes the perovskite surface, while the hydrophobic fluorinated moieties prevent the ingress of water and oxygen, enhancing the device stability. The resultant devices achieve a power conversion efficiency (PCE) of 24.6%. The unencapsulated devices retain 91% of their initial efficiency after 1000 h in air with 60% relative humidity, and 95% after 500 h under maximum power point (MPP) tracking at 35 °C. The utilization of multifunctional dipole molecules opens new avenues for high‐performance and long‐term stable perovskite devices.
Hierarchical Composites Patterned via 3D Printed Cellular Fluidics
Authors: Gemeda Hawi B. , Dudukovic Nikola A. , Zhu Cheng , Guell Izard Anna , Gongora Aldair E. , Deotte Joshua R. , Davis Johnathan T. , Duoss Eric B. , Fong Erika J. 
Published: July 2024

AbstractAdditive manufacturing of freeform structures containing multiple materials with deterministic spatial arrangement and interactions remains a challenge for most 3D printing processes, due to complex fabrication tool requirements and limitations in printability of some material classes. Here, a versatile method is reported to produce architected composites using the concept of cellular fluidics, in which lattices of unit cells are used as templating scaffolds to guide flowable infill materials in a programmed spatial pattern, upon which they are cured in place to produce a deterministically ordered multimaterial solid. The lattice design relies on the unit cell size, type, strut diameter, surface wetting, and distribution of cellular structures to control liquid flow and retention. Individual unit cells are tuned to achieve reliable infilling and combined into higher‐order architectures to achieve multiscale composite materials with disparate mechanical properties, including those considered non‐printable. Lattice design considerations for leveraging capillary phenomena and demonstrate several methods of patterning polymers in 3D‐printed cellular fluidic structures are presented. The concept of tuning the compressive response of an architected composite using a flexible‐elastomer as the lattice and a stiff‐epoxy as the infill material is illustrated.
Exploring the Ultralong Lifetime of Self‐matrix 1,10 Phenanthroline and Boron‐Based Room Temperature Phosphorescence Carbon Dots for Multiple Applications
Authors: Pricilla R. Blessy , Urbanek Pavel , Sevcik Jakub , Skoda David , Antos Jan , Munster Lukas , Domincova‐Bergerova Eva , Kuritka Ivo 
Published: July 2024

AbstractRoom temperature phosphorescence carbon dots (RTP CDs) are one of the newly investigated nanomaterials because of their remarkable optical characteristics. They are widely utilized in many versatile optoelectronic and security applications. Apart from synthesis, one of its challenging attributes is its lifetime at room temperature. Here, a straightforward and quick heating approach is presented for synthesizing self‐matrix 1,10 phenanthroline and boron‐based RTP CDs. 1,10 phenanthroline is utilized as an aromatic and hetero atom containing carbon precursor and boric acid is used as a passivating to stabilize the triplet excitons and prevent nonradiative deactivation. Various characterization techniques like TEM, XRD, FTIR, UV–vis, PL, and elemental analysis (ICP and CHNS) have been used to study the properties of self‐matrix RTP CDs. The RTP CDs exhibited excellent blue‐green emission when excited at 302 nm. Compared to the available literature, the novelty of this work is observed from its high naked eye phosphorescence characteristic of ≈22 s with an average lifetime of ≈ 2.4 s at 302 nm, making them ultralong self‐matrix RTP CD material. Due to their exceptional qualities, the self‐matrix RTP CDs have been widely employed for various applications, including information encryption decryption, phosphor for LEDs, anticounterfeiting, and water sensitivity analysis.
KAT6A Condensates Impair PARP1 Trapping of PARP Inhibitors in Ovarian Cancer
Authors: Zhan Zhiyan , Zhang Jiarong , Liang Huisheng , Wang Chong , Hong Li , Liu Wenxue 
Published: July 2024

AbstractMost clinical PARP inhibitors (PARPis) trap PARP1 in a chromatin‐bound state, leading to PARPi‐mediated cytotoxicity. PARPi resistance impedes the treatment of ovarian cancer in clinical practice. However, the mechanism by which cancer cells overcome PARP1 trapping to develop PARPi resistance remains unclear. Here, it is shown that high levels of KAT6A promote PARPi resistance in ovarian cancer, regardless of its catalytic activity. Mechanistically, the liquid‐liquid phase separation (LLPS) of KAT6A, facilitated by APEX1, inhibits the cytotoxic effects of PARP1 trapping during PARPi treatment. The stable KAT6A‐PARP1‐APEX1 complex reduces the amount of PARP1 trapped at the DNA break sites. In addition, inhibition of KAT6A LLPS, rather than its catalytic activity, impairs DNA damage repair and restores PARPi sensitivity in ovarian cancer both in vivo and in vitro. In conclusion, the findings demonstrate the role of KAT6A LLPS in fostering PARPi resistance and suggest that repressing KAT6A LLPS can be a potential therapeutic strategy for PARPi‐resistant ovarian cancer.
Distinct Thalamo‐Subcortical Circuits Underlie Painful Behavior and Depression‐Like Behavior Following Nerve Injury
Authors: Deng Jie , Chen Li , Liu Cui‐Cui , Liu Meng , Guo Guo‐Qing , Wei Jia‐You , Zhang Jian‐Bo , Fan Hai‐Ting , Zheng Zi‐Kun , Yan Pu , Zhang Xiang‐Zhong , Zhou Feng , Huang Sui‐Xiang , Zhang Ji‐Feng , Xu Ting , Xie Jing‐Dun , Xin Wen‐Jun 
Published: July 2024

AbstractClinically, chronic pain and depression often coexist in multiple diseases and reciprocally reinforce each other, which greatly escalates the difficulty of treatment. The neural circuit mechanism underlying the chronic pain/depression comorbidity remains unclear. The present study reports that two distinct subregions in the paraventricular thalamus (PVT) play different roles in this pathological process. In the first subregion PVT posterior (PVP), glutamatergic neurons (PVPGlu) send signals to GABAergic neurons (VLPAGGABA) in the ventrolateral periaqueductal gray (VLPAG), which mediates painful behavior in comorbidity. Meanwhile, in another subregion PVT anterior (PVA), glutamatergic neurons (PVAGlu) send signals to the nucleus accumbens D1‐positive neurons and D2‐positive neurons (NAcD1→D2), which is involved in depression‐like behavior in comorbidity. This study demonstrates that the distinct thalamo‐subcortical circuits PVPGlu→VLPAGGABA and PVAGlu→NAcD1→D2 mediated painful behavior and depression‐like behavior following spared nerve injury (SNI), respectively, which provides the circuit‐based potential targets for preventing and treating comorbidity.
Wet Chemistry Route to Li3InCl6: Microstructural Control Render High Ionic Conductivity and Enhanced All‐Solid‐State Battery Performance
Authors: Bonsu Jacob Otabil , Bhadra Abhirup , Kundu Dipan 
Published: July 2024

AbstractThanks to superionic conductivity and compatibility with >4 V cathodes, halide solid electrolytes (SEs) have elicited tremendous interest for application in all‐solid‐state lithium batteries (ASSLBs). Many compositions based on groups 3, 13, and divalent metals, and substituted stoichiometries have been explored, some displaying requisite properties, but the Li+conductivity still falls short of theoretical predictions and appealing sulfide‐type SEs. While controlling microstructural characteristics, namely grain boundary effects and microstrain, can boost ionic conductivity, they have rarely been considered. Moving away from the standard solid‐state route, here a scalable and facile wet chemical approach for obtaining highly conductive (>2 mS cm−1) Li3InCl6is presented, and it is shown that aprotic solvents can reduce grain boundaries and microstrain, leading to very high ionic conductivity of over 4 mS cm−1(at 22 °C). Minimized grain boundary area renders improved moisture stability and enhances solid–solid interfacial contact, leading to excellent LiNi0.6Mn0.2Co0.2O2‐based full‐cell performance, exemplified by stable room temperature (22 °C) cycling at a 0.2 C rate with 155 mAh g−1capacity and 85% retention after 1000 cycles at 60 °C with a high 99.75% Coulombic efficiency. The findings showcase the viability of the aprotic solvent‐mediated route for producing high‐quality Li3InCl6for all‐solid‐state batteries.