bluuebunny/crossref_metadata_2025_split huggingface dataset:
Single‐Pot Synthesis and Optimization of CCF@GO Nanocatalyst for Efficient Direct Oxidative Amidation of Carboxylic Acids and N,N‐Dialkylformamides
Authors: Pawar Mahesh A. , Nakhate Akhil V. , Ugemuge Priti V. , Kadu Samidha S. , Tekade Pradip V. 
Published: August 2024

ABSTRACTIn this study, an efficient catalytic protocol using CuCoFe2O4@GO (CCF@GO) for the synthesis of amide bond (−CONH−) via direct coupling of carboxylic acids and N,N‐dialkylformamides is presented. The CCF@GO nanocatalyst has been synthesized via a single‐pot solvothermal method, by changing the proportions of copper and cobalt (1:1, 1:3, and 3:1). Catalyst screening, employing a model reaction with benzoic acid and dimethylformamide (DMF), revealed that the 1:1 proportion of CCF@GO catalyst exhibited excellent efficiency, achieving a high conversion (98%) towards amide formation. The enhanced catalytic efficiency observed in CCF@GO catalysts can be ascribed to the uniform distribution of active copper and cobalt species on the graphene oxide support, which possesses a high surface area. Optimization of the reaction was conducted by varying parameters such as temperature, solvent, catalyst loading, and oxidant. The prepared catalyst was characterized using various analytical techniques including XRD, FTIR, XPS, SEM, EDX mapping, and TEM. Furthermore, this heterogeneous nanocatalyst demonstrated recoverability using an external magnet and reused up to five times with just a modest loss of catalytic performance.
Leveraging Consistent Communication Tools and Organizational Values to Promote Accountability Among Health Care Providers
Authors: Baldwin Cynthia A. , Krumm Alice M. 
Published: August 2024

ABSTRACTTeamwork and effective communication between all health care staff members are essential to providing safe, high‐quality patient care. High‐reliability organizations align behavioral expectations with organizational values and prioritize safety over other performance metrics and pressures. Communication breakdowns, such as inadequate or incomplete information shared between caregivers, continues to be an issue that is linked to errors and staff member dissatisfaction. Initiatives to improve health care communication and improve patient outcomes are well documented, yet communication issues in the health care setting continue. An organization's credo defines its values and behavioral expectations. Educating team members on an organization's credo creates accountability among those teams to align their behavior with the organization's values, policies, and professional commitment. A Coworker Observation Reporting System offers a communication method for providing meaningful feedback on behaviors inconsistent with an organization's credo.
Preparation of a novel polyvinyl chloride ultrafiltration membrane modified with graphene oxide nanoparticle derived from plastic waste for wastewater purification
Authors: Heidari Behnoush , Mahmoudi Jafar , Hedayat Seyyed Mahdi , Masoomi Seyyed Roohollah 
Published: August 2024

AbstractThe purpose of this study is to improve the performance of polyvinyl chloride (PVC) ultrafiltration membrane with graphene oxide (GO) that was synthesized from the pyrolysis of polypropylene (PP) bottles. The amount of GO loading in the membrane structure was 0.05, 0.15, and 0.25 wt%. x‐ray diffractometer, FTIR, scanning electron microscopy (SEM), contact angle (CA), water content, porosity, mechanical strength were used to characterize the synthesized membranes. Cross‐sectional SEM results of membranes indicated that the modification of the membrane caused the formation of finger‐like pores in the bottom part and also these holes increased the dye rejection efficiency in the membranes of (18 wt% PVC/2 wt% PVP/0.15 wt% GO) and (14 wt% PVC/2 wt% PVP/0.25 wt% GO). The CA of the synthesized membranes were decreased from 70 in (18 wt% PVC/2 wt% PVP) to 62 in (14 wt% PVC/2 wt% PVP/0.15 wt% GO), which indicates the increase in hydrophilicity of these membranes. The results showed that the best performance is related to the membranes (18 wt% PVC/2 wt% PVP/0.15 wt% GO) and (14 wt% PVC/2 wt% PVP/0.25 wt% GO) with a rejection efficiency of 92% and 83% for 100 ppm methyl blue.
Nucleating agent for polypropylene comprising the calcium salt of 4‐methyl‐cyclohexane‐1,2‐dicarboxylic acid
Authors: Inoue Takahiro , Inoue Mitsuko , Matsumoto Kazuya , Iwasaki Shohei , Yamaguchi Masayuki 
Published: August 2024

AbstractIn the present study, a novel crystalline nucleating agent for isotactic polypropylene (PP) comprising the calcium salt of 4‐methyl‐cyclohexane‐1,2‐dicarboxylic acid (MHPA‐Ca) is developed. The performance of the nucleating agent is evaluated by determining the crystallization temperature and isothermal crystallization period of the PP by differential scanning calorimetry, and comparing them with those obtained using the calcium salt of cyclohexane‐1,2‐dicarboxylic acid (HHPA‐Ca), which is one of the most effective nucleating agents for PP. The results demonstrate that the nucleating ability of MHPA‐Ca is much stronger than that of HHPA‐Ca. Consequently, an injection‐molded plate containing MHPA‐Ca has a high degree of chain orientation.
Life After Death: Re‐Purposing End‐of‐Life Supercapacitors for Electrochemical Water Desalination
Authors: Ren Panyu , Torkamanzadeh Mohammad , Arnold Stefanie , Pameté Emmanuel , Presser Volker 
Published: August 2024

AbstractThis study explores the potential of re‐purposing end‐of‐life commercial supercapacitors as electrochemical desalination cells, aligning with circular economy principles. A commercial 500‐Farad supercapacitor was disassembled, and its carbon electrodes underwent various degrees of modification. The most straightforward modification involved NaOH‐etching of the aluminum current collector to produce free‐standing carbon films. More advanced modifications included CO2 activation and binder‐added wet processing of the electrodes. When evaluated as electrodes for electrochemical desalination via capacitive deionization of low‐salinity (20 mM) NaCl solutions, the minimally modified NaOH‐etched carbon electrodes achieved an average desalination capacity of 5.8 mg g−1 and a charge efficiency of 80 %. In contrast, the CO2‐activated, wet‐processed electrodes demonstrated an improved desalination capacity of 7.9 mg g−1 and a charge efficiency above 90 % with stable performance over 20 cycles. These findings highlight the feasibility and effectiveness of recycling supercapacitors for sustainable water desalination applications, offering a promising avenue for resource recovery and re‐purposing in pursuing environmental sustainability.
Reference‐Dependent Risk‐Taking in the NBA
Authors: Mochon Daniel 
Published: August 2024

ABSTRACTThis paper examines whether risk preferences in the NBA are reference‐dependent and attempts to identify the reference point. Using data from 10 NBA seasons (12,890 games), I find that teams are more likely to attempt a riskier three‐point shot (vs. a less risky two‐point shot) when below the reference point than above it, consistent with Prospect Theory. The results further show that teams are not influenced by a single fixed reference point, but instead, their choices depend on the score difference, most recent score change, and pregame expectations. Additionally, the weight given to the reference point changes over the course of the game. Teams show a breakeven effect, such that they are more likely to attempt a three‐point shot when doing so can tie the game. They also show behavior consistent with mental accounting, as the reference point carries more weight at the end of a quarter than at the beginning. These results provide further real‐world evidence for reference‐dependent risk preferences while highlighting the challenge of applying reference‐dependent models to real‐world settings.
Whole Exome Sequencing Revealing a Novel PBX1 Gene Variant in a Chinese Family Causing Recurrent Neonatal Death
Authors: Huang Nan , Zhang Hegan , Huang Zhengping , Wu Xiaoxia , Zhang Na , Jiang Yuying , Chen Chunnuan , Zhuang Jianlong 
Published: August 2024

ABSTRACTBackgroundCausative mutations of PBX1 are associated with congenital abnormalities of the kidney and urinary tract (CAKUT), often accompanied by hearing loss, abnormal ear morphology, or developmental delay. The aim of the present investigation was to introduce a novel variant in the PBX1 gene identified in a Chinese family, leading to recurrent neonatal mortality.MethodsA pregnant woman (gravida 5, para 0), who had experienced recurrent neonatal deaths, sought genetic etiology diagnosis. Whole exome sequencing (WES) was conducted to identify sequence variants and copy number variants in the fetus presenting with posterior nuchal cystic hygroma and fetal hydrops.ResultsA novel NM_002585.4:c.694G>C(p.D232H) in PBX1 was identified in the fetus through trio whole exome sequencing (WES), revealing a paternal mosaic PBX1 variant in blood at 11.54% (6/52 variants reads). Subsequent parental Sanger sequencing confirmed the variant detected by WES. Ultimately, the variant was classified as likely pathogenic, leading the family to elect pregnancy termination at 17 weeks gestation.ConclusionThe novel variant in the PBX1 gene appears to be a significant factor contributing to recurrent neonatal deaths in the Chinese family. Such findings expand the spectrum of PBX1 gene variants and provide valuable perinatal guidance for diagnosing fetuses with PBX1 mutations.
Harnessing the therapeutic potential of phytochemicals in neuroblastoma
Authors: Ahmadi Seyed Sajad , Bagherzadeh Omid , Sargazi Meysam , Kalantar Farnaz , Najafi Mohammad Amin Elahi , Vahedi Mohammad Mahdi , Afshari Amir R. , Sahebkar Amirhossein 
Published: August 2024

AbstractNeuroblastomas are the most common solid tumors outside of the brain that originate from immature neural crest cells, accounting for about 10% of all pediatric malignancies. The treatment for neuroblastomas involves a multimodal schedule, including surgery, radiation, chemotherapy, and immunotherapy. All these modalities are limited by side effects that might be severe, poor prognosis, and a high risk of recurrence. In the quest for additional therapeutic approaches, phytochemicals have attracted attention owing to their reported antitumor properties, safety, and multimechanistic mode of action. Several studies have used plant‐derived bioactive compounds such as phenolics and flavonoids, suggesting modulation of biomolecules and signal transduction pathways involved in neuroblastoma. We reviewed the findings of recent preclinical and clinical studies demonstrating the effects of phytochemicals on neuroblastoma, shedding light on their molecular mechanism of action and potential therapeutic applications.
Elucidating plasmon damping in silver‐coated gold nanorods: Single particle analysis and damping adjustment
Authors: Raihana Syam Rafifah Hana , Ha Ji Won 
Published: August 2024

AbstractWe demonstrate the morphology and spectral properties of silver‐coated gold nanorods (AuNRs@Ag), synthesized via seed‐mediated growth, using scanning electron microscopy (SEM) and dark‐field (DF) spectroscopy. The relationship between surface damping and the thickness of the Ag shell in AuNRs was analyzed at the single‐particle level. Additionally, we adjusted the bulk damping and radiation damping of AuNRs to elucidate the contribution of surface damping. SEM images demonstrated an increase in length and width following Ag deposition. Elemental mapping analysis confirmed the Ag deposition on the AuNR surface, with Ag content measured at 26.7% for AuNR@Ag26.7 with a 1‐day incubation period and 34.8% for AuNR@Ag34.8 with a 2‐day incubation period. DF spectroscopy revealed a notable blue shift and slight broadening in their LSPR spectra. Moreover, surface damping decreased with an increase in Ag content. Consequently, this study advances the understanding of plasmon damping mechanisms in single AuNR@Ag for their potential applications.
Specific DNA aptamer–immobilized cryogel membranes as novel bioaffinity supports and their potential for the purification of activated protein C
Authors: Aliyeva Nilufer , Akgönüllü Semra , Erdem Arzum , Denizli Adil 
Published: August 2024

AbstractActivated protein C (APC), a serine protease produced from zymogen protein C (PC), is the key enzyme of the protein C pathway. APC has anticoagulant, anti‐inflammatory, and cytoprotective features. APC has recently been shown to significantly reduce coagulation as well as mortality in patients with severe sepsis. Herein, we aimed to develop an affinity support material that allows the purification of plasma APC for the first time. In this research, a novel APC‐specific DNA aptamer–based poly(2‐hydroxyethyl methacrylate‐glycidyl methacrylate) (poly(HEMA‐GMA/DNA‐Apt)) macroporous cryogel membrane at different molar ratios was prepared using affinity binding method and their potential for purification and identification of APC was investigated. The DNA aptamer–immobilized cryogels were characterized to examine their structural and morphological properties. The effect of pH, initial concentration, temperature, ionic strength difference, and flow rate changes was examined. Selectivity studies were performed in the presence of APC and competitive proteins, and cryogel support materials were shown to have a very high affinity for APC. Adsorption capacity was found to be 89.02 mg/g. Finally, NaCl revealed efficiency for APC desorption and the reuse of cryogels was successfully tested for ten cycles.
Risk factors for lenvatinib‐induced palmar‐plantar erythrodysesthesia syndrome in patients with hepatocellular carcinoma: A retrospective study
Authors: Uekusa Shusuke , Nemoto Maho , Hanai Yuki , Nakashin Misaki , Yanagino Sachiko , Arita Yoshiki , Matsumoto Takahiro , Wakui Noritaka , Nagai Hidenari , Higai Koji , Matsuo Kazuhiro 
Published: August 2024

AbstractAimLenvatinib mesylate (LEN) is an oral tyrosine kinase inhibitor used to treat various cancers, including hepatocellular carcinoma (HCC). HCC treatment with LEN is associated with a very high incidence of adverse events. This study was aimed at investigating the incidence of LEN‐induced palmar‐planter erythrodysesthesia syndrome (PPES) and its relationship with patient demographics by analyzing clinical laboratory data of LEN‐treated patients with HCC.MethodsThis was a single‐centre, retrospective study of patients with HCC who received LEN between April 19, 2018, and September 30, 2020. The observation period was from 1 week before the start of LEN administration to 1 month after the end of administration.ResultsOverall, 75 patients with HCC were enrolled. LEN‐induced PPES was found in 48.0% (36/75 patients). In these patients, alkaline phosphatase (ALP), γ‐Glutamyl transpeptidase (γ‐GTP) and monocytes (MONO) were significantly high (ALP: p = 1.32 × 10−3, γ‐GTP: p = 4.25 × 10−3 and MONO: p = 0.013). The cut off values of ALP, γ‐GTP and MONO for LEN‐induced PPES were estimated at 573 U/L, 89 U/L, and 310 counts/μL, respectively. In the multivariate analysis, γ‐GTP and MONO were independent risk factors for LEN‐induced PPES.ConclusionsHigh γ‐GTP and high MONO were risk factors for LEN‐induced PPES.
Trends in HPV‐associated cancer incidence in Texas medically underserved regions
Authors: Hoang Thao N. , Berenson Abbey B. , Shan Yong , Guo Fangjian , Adekanmbi Victor , Hsu Christine , Yu Xiaoying , Kuo Yong‐Fang 
Published: August 2024

AbstractBackgroundWhile cervical cancer incidence rates (IR) in the United States have dropped in the last 20 years, non‐cervical human papillomavirus (HPV) associated cancers increased. Many people in Texas (TX) live in medically underserved areas and have higher risk of developing HPV‐associated cancers. Since previous studies of these regions focused on cervical cancer, we included other HPV‐associated cancers in our analysis of IR in East TX and the TX‐Mexico Border compared to other TX regions.MethodsCancer data from 2006 to 2019 were obtained from the TX Cancer Registry. Cases of HPV‐associated cervical, vaginal, vulvar, penile, anal, and oropharyngeal cancers and corresponding patient‐level demographic data were included. We calculated IR per 100,000 and drew heat maps to visualize cancer IR by county. To control potential confounders, we added county‐level risk factors: rates for smoking, excessive drinking, obesity, STIs, primary care provider availability and dentist availability, from the County Health Rankings and Roadmaps program. We reported IRs by region and time and estimated unadjusted and adjusted risk ratio (RR) for association of each type of cancer and region. Lastly, we created adjusted models for each cancer by period to see time trends of regional differences.ResultsRisk of anal, cervical, and oropharyngeal cancer was lower at parts of the Border than in the rest of TX in the adjusted model. We also observed increasing anal and oropharyngeal cancer risk and decreasing cervical and vaginal cancer risk over time.ConclusionPatient sociodemographics, behavioral risk factors, and access to care may contribute to some observed differences in cancer IR across regions. This indicates that targeted prevention efforts towards these regions, especially in low socioeconomic status communities, may benefit future generations.
Minor Humulane and Eremophilane Sesquiterpenoids from Syringa pinnatifolia and Their Protective Effect Against Oxidative Injuries in H9c2 Cells
Authors: Sun Jingjing , Chen Panlong , Liu Changxin , Zhang Zefeng , Kang Lulu , Ren Gang , Gao Xiaoli , Cao Lan , Chai Xingyun 
Published: August 2024

AbstractAs a part of systematic research, an ongoing phytochemical investigation of the sesquiterpenoid‐containing fraction led to the isolation of five new sesquiterpenoids from the peeled stems of Syringa pinnatifolia, including two pairs of enantiomeric humulane‐type (±)‐alashanoids A1 and B1 (1 and 2) and one eremophilane‐type alashanoid C1 (3). These structures were elucidated by the analysis of extensive spectroscopic data, including ESI‐MS and 1D and 2D NMR, and the absolute configuration was determined by comparing its experimental and calculated electronic circular dichroism and calculated NMR. These isolates exhibited moderate in vitro cardioprotective effects against oxidative injuries in H9c2 cells.
Understanding the Environmental Sensitivity of Copper‐Metal Oxides Interactions in Cu/ZnO and Cu/Al2O3 Catalysts
Authors: Jiang Zhaocong , Li Didi , Gu Haoyuan , Jin Shiqing , Zhu Minghui 
Published: August 2024

AbstractTernary Cu/ZnO/Al2O3 catalysts are one of the most important industrial catalysts and show excellent activity in methanol reforming reaction. However, it is challenging to elucidate the metal support interactions, which critically influence the catalyst structure and performance, due to their environmentally sensitive nature. This study examines the interactions between Cu and Al2O3 and ZnO, after reductive treatments of the Cu/Al2O3 and Cu/ZnO model catalysts with varying temperatures and hydrogen concentration. A combination of Brunner‐Emmet‐Teller (BET) measurements, X‐ray diffraction (XRD), N2O titration, diffuse reflectance infrared Fourier transformations spectroscopy (DRIFTS) and high‐resolution transmission electron microscopy (HRTEM) provided comprehensive insights into the structural evolution of the catalysts.
Population Power Curves in ASCA With Permutation Testing
Authors: Camacho José , Sorochan Armstrong Michael 
Published: August 2024

ABSTRACTIn this paper, we revisit the power curves in ANOVA simultaneous component analysis (ASCA) based on permutation testing and introduce the population curves derived from population parameters describing the relative effect among factors and interactions. The relative effect has important practical implications: The statistical power of a given factor depends on the design of other factors in the experiment and not only of the sample size. Thus, understanding the relative power in a specific experimental design can be extremely useful to maximize our capability of success when planning the experiment. In the paper, we derive relative and absolute population curves, where the former represent statistical power in terms of the normalized effect size between structure and noise, and the latter in terms of the sample size. Both types of population curves allow us to make decisions regarding the number and nature (fixed/random) of factors, their relationships (crossed/nested), and the number of levels and replicates, among others, in an multivariate experimental design (e.g., an omics study) during the planning phase of the experiment. We illustrate both types of curves through simulation.
Emerging Mixed‐Valence Porous Materials
Authors: Kaveevivitchai Watchareeya , Chen Teng‐Hao 
Published: August 2024

AbstractThe development and applications of porous materials have been revolutionized over the past decades. To fine‐tune their fascinating behaviors such as charge‐transport, magnetic, and catalytic properties, one of the most effective strategies is incorporating mixed valency into the structures. This Concept provides recent progress on emerging crystalline porous materials, namely, metal–organic frameworks, metal–organic polyhedra, covalent organic frameworks, and hydrogen‐bonded organic frameworks, where their mixed valency is either intrinsic or postsynthetically induced via an external stimulus. We further highlight the investigation of mixed valency and potential applications, which sheds light on the design and exploitation of mixed‐valence crystalline porous materials.
Investigating new solutions for a general form of q$$ \mathfrak{q} $$‐deformed equation: An analytical and numerical study
Authors: Ali Khalid K. , Mohamed Mohamed S. , Alharbi Weam G. 
Published: August 2024

SummaryThis paper contributes to the study of a new model called the ‐deformed equation or the ‐deformed tanh‐Gordon model. To understand physical systems with violated symmetries. We utilize the ‐expansion approach to solve the ‐deformed equation for specific parameter values. This method generates solutions that provide valuable insights into the system's dynamics and behavior. To verify the accuracy of our solutions, we also apply the finite difference technique to obtain numerical solutions to the ‐deformed equation. This dual approach ensures the reliability of our results. We present our findings using tables and graphics to enhance clarity and facilitate comparison between the analytical and numerical solutions. These visual aids help readers better understand the similarities and differences between the two approaches. The ‐deformation is significant as it models physical systems with nonstandard symmetry features, like extensivity, offering a more accurate representation of real‐world phenomena. The growing significance of this equation across various disciplines highlights its potential in advancing our understanding of complex physical systems. This paper contributes valuable knowledge about the ‐deformed equation, demonstrating its potential for accurately modeling physical systems with violated symmetries. Through both analytical and numerical techniques, we offer comprehensive solutions and validate their accuracy, with graphical representations enhancing the clarity and understanding of our results. This exploration of ‐deformation advances modeling techniques, providing a more precise depiction of real‐world processes with nonstandard symmetry features.