bluuebunny/crossref_metadata_2025_split huggingface dataset:
Numerical solution for the interior electric displacement of the moving DBY‐PS model for semi‐permeable cracked piezoelectric material
Authors: Singh Vikram , Jangid Kamlesh 
Published: August 2024

AbstractIn this study, we analysed a moving crack at the interface of an infinitely long piezoelectric bilayer using the Dugdale–Barenblatt yield (DBY) model and the polarisation saturation (PS) model. To model the moving crack problem, a Yoffe‐type crack moves at a constant subsonic speed on the interface of an infinitely long piezoelectric bilayer. The crack faces are assumed to be semi‐permeable, and at the boundary of the bilayer, in‐plane electrical and out‐of‐plane mechanical stresses are applied. Due to the application of electro‐mechanical loads, cracks propagate, mechanical yielding zones and electric saturation zones are developed. To arrest the crack from further propagation, mechanical yield stress and saturation electric displacement are applied at the developed zones. To address this problem analytically and numerically, the mixed boundary value problem is transformed into a set of coupled Fredholm integral equations (FIEs) of the second kind using the Fourier transform and the Copson method. The closed‐form analytical expressions for the length of the electrical saturation zone (ESZ), whether longer, shorter or equal to the mechanical yielding zone (MYZ), show dependence on external electro‐mechanical loads under semi‐permeable crack conditions. The algorithm to solve the electric crack condition parameter (ECCP) has been defined using numerical discretization and the bisection method. Illustrative examples demonstrate the proposed technique's effectiveness and suitability for Yoffe‐type moving cracks. The numerical results show the convergence of the ECCP. Furthermore, the numerical results show how mechanical and electrical zone lengths and energy release rate (ERR) are affected by electrical and mechanical loads, strip thickness and crack velocity. In addition, the size of the mechanical yielding zone is consistently promoted by electrical load, while the promotion or prevention of the electrical saturation zone by mechanical load depends on the relative sizes of the nonlinear zones.
Revisiting Maximum Log-Likelihood Parameter Estimation for Two-Parameter Weibull Distributions: Theory and Applications
Authors: Kneib Thomas , Schlüter Jan-Christian , Wacker Benjamin 
Published: August 2024

AbstractIn this article, we reexamine properties of maximum log-likelihood parameter estimation for two-parameter Weibull distributions which have been applied in many different sciences. Finding reasons for this popularity is a key question. Our main contribution is a thorough existence and uniqueness proof for a global maximizer with respect to the parameter space. We first provide existence and uniqueness of local maximizers by Schauder’s first fixed point theorem, monotony arguments and local concavity of its Hessian matrix. Thus, we can prove our main result of existence and uniqueness of a global maximizer by considering all limiting cases with respect to the parameter space. We finally strengthen our theoretical findings on four data sets. On the one hand, two synthetic data sets underline our need for our data assumptions while, on the other hand, we choose two data sets from wind engineering and reliability engineering to demonstrate usefulness in real-world applications.
Classical and generalized solutions of an alarm-taxis model
Authors: Fuest Mario , Lankeit Johannes 
Published: August 2024

AbstractIn bounded, spatially two-dimensional domains, the system "Equation missing"complemented with initial and homogeneous Neumann boundary conditions, models the interaction between prey (with density u), predator (with density v) and superpredator (with density w), which preys on both other populations. Apart from random motion and prey-tactical behavior of the primary predator, the key aspect of this system is that the secondary predator reacts to alarm calls of the prey, issued by the latter whenever attacked by the primary predator. We first show in the pure alarm-taxis model, i.e. if $$\xi = 0$$

ξ
=
0

, that global classical solutions exist. For the full model (with $$\xi > 0$$

ξ
>
0

), the taxis terms and the presence of the term $$-a_2 uw$$

-

a
2

u
w

in the first equation apparently hinder certain bootstrap procedures, meaning that the available regularity information is rather limited. Nonetheless, we are able to obtain global generalized solutions. An important technical challenge is to guarantee strong convergence of (weighted) gradients of the first two solution components in order to conclude that approximate solutions converge to a generalized solution of the limit problem.
Social connection interventions and depression in young adults: a systematic review and meta-analysis
Authors: Alvarez Clotilde Vazquez , Mirza Luwaiza , Das-Munshi Jayati , Oswald Tassia Kate 
Published: August 2024

Abstract

Purpose
Early adulthood is a period which may increase vulnerability to loneliness and mental health difficulties among young adults. Social networks play an important role in buffering against adverse mental health, but there is a lack of evidence around whether social connection interventions could play a role in preventing mental health difficulties for young adults.

Methods
A systematic review and meta-analysis was conducted (PROSPERO ID: CRD42023395595). PubMed, PsycInfo, and Scopus were searched (01 January 2000–01 January 2023). Studies were eligible if they (i) were quantitative, (ii) included young adults (18–24 years) from the general population, (iii) tested a social intervention which aimed to increase the quantity or quality of social connections or reduce loneliness, (iv) had a comparison group, and (v) measured depression and loneliness/social connection as outcomes. Following study screening and selection, the data extraction and risk of bias assessments were independently conducted in duplicate. The Cochrane RoB-2 tool and ROBINS-I tool were used to assess risk of bias. Results were narratively synthesised and random effects meta-analysis with standardised mean differences was conducted.

Results
Six studies were included; four in-person interventions with higher education students, one online intervention with higher education students, and one intervention for youth involved in street life. The studies were mostly rated as having some or moderate concerns with risk of bias. The interventions were associated with an overall mean reduction in depression for young adults (SMD = -0.19; 95% CI, -0.33 to -0.05; p = 0.008; 4 studies, excluding studies with serious risk of bias). All interventions had beneficial effects on a range of diverse social connection outcomes, but there was no overall statistically significant mean reduction in loneliness for young adults in pooled analyses (SMD = -0.10; 95% CI, -0.24 to 0.05; p = 0.188; 3 studies).

Conclusion
Social connection interventions show some promise in improving depression and social connection outcomes in young adults but more high-quality research, across diverse settings, is needed in this area.
Drawing the full picture on diverging findings: adjusting the view on the perception of art created by artificial intelligence
Authors: Neef Nicolas E. , Zabel Sarah , Papoli Maria , Otto Siegmar 
Published: August 2024

AbstractAI is becoming increasingly prevalent in creative fields that were thought to be exclusively human. Thus, it is non-surprising that a negative bias toward AI-generated artwork has been proclaimed. However, results are mixed. Studies that have presented AI-generated and human-created images simultaneously have detected a bias, but most studies in which participants saw either AI-generated or human-created images have not. Therefore, we propose that the bias arises foremost in a competitive situation between AI and humans. In a sample of N = 952 participants, we show that different evaluations emerge only when AI-generated and human-created pieces of art are presented simultaneously. Importantly, we demonstrate that AI art is not devalued, but rather, human art is upvalued, indicating the existence of a positive bias toward humans, rather than a negative bias. Further, we show that attitudes toward AI and empathy partially explain the different valuations of AI and human art in competitive situations.
Vertical margin distance in T1 colorectal carcinoma resected by endoscopic submucosal dissection affects prognosis after additional surgery
Authors: Tanino Fumiaki , Yamashita Ken , Nagata Shinji , Kuwai Toshio , Kamigaichi Yuki , Tanaka Hidenori , Tamaru Yuzuru , Takigawa Hidehiko , Asayama Naoki , Urabe Yuji , Shimamoto Fumio , Oka Shiro 
Published: August 2024

Abstract
Purpose
A vertical margin (VM) distance of < 500 µm is a risk factor for recurrence in patients with T1 colorectal carcinoma (CRC) resected by endoscopy. We aimed to determine the effects of the VM distance on the recurrence and prognosis of T1 CRC.

Methods
We enrolled 168 patients with T1 CRC who underwent additional surgery after endoscopic submucosal dissection (ESD) at multiple centers between 2008 and 2016. None of the patients were followed up for < 5 years. The enrolled 168 patients were classified into patients with VM distance of < 500 µm including positive VM (n = 72 [43%], VM distance < 500 µm group) and patients with VM distance of ≥ 500 µm (n = 96 [57%], VM distance ≥ 500 µm group). The clinicopathological features, recurrence rates, and prognoses were compared between the groups using propensity-score matching (PSM).

Results
Tumors recurred in eight of the 168 patients (5%) with VM distance < 500 µm. After PSM, the rate of overall recurrence and local recurrence in the VM distance < 500 µm group were significantly higher than those in the VM distance ≥ 500 µm group. The 5-year recurrence-free survival rate was significantly higher in the VM distance ≥ 500 µm group than that in VM distance < 500 µm group after PSM (100% vs. 89%, p < 0.012).

Conclusions
Complete en bloc resection of T1 CRC via ESD must include a sufficient amount of SM to reduce the risk of metastasis and recurrence after additional surgery.
Hysteroscopy: where did we start, and where are we now? The compelling story of what many considered the “Cinderella” of gynecological endoscopy
Authors: Vitale Salvatore Giovanni , Giannini Andrea , Carugno Jose , van Herendael Bruno , Riemma Gaetano , Pacheco Luis Alonso , Drizi Amal , Mereu Liliana , Bettocchi Stefano , Angioni Stefano , Haimovich Sergio 
Published: August 2024

AbstractHysteroscopy has truly revolutionized the field of diagnostic and operative gynecology. It is presently regarded as the gold standard method for both the diagnosis and treatment of intrauterine diseases and it has fundamentally altered the way gynecologists treat patients with such conditions. These pathologies can now be diagnosed and treated in an outpatient setting, thanks to technological advancements and instrument downsizing. Two hundred years of development and notable innovation are now reflected in the present hysteroscopic practice. This review attempts to trace the boundaries-pushing history of hysteroscopy by highlighting the advancements in technology and the therapeutic and diagnostic benefits offered by this groundbreaking approach.
Magnetic resonance imaging evaluation of cochlear and vestibular nerve calibre: a case-control study in Ménière’s disease and endolymphatic hydrops
Authors: Khalifa Radwa , Touska Philip , Pai Irumee , Padormo Francesco , Goh Vicky , Hajnal Joseph V. , Connor Steve E. J. 
Published: August 2024

Abstract

Purpose
To compare the calibre of the cochlear (CN), superior vestibular (SVN) and inferior vestibular (IVN) nerves on magnetic resonance imaging (MRI), both between Ménière’s Disease (MD) ears and clinical controls, and between inner ears with and without endolymphatic hydrops (EH) on MRI.

Methods
A retrospective case–control study evaluated patients undergoing MRI for suspected hydropic ear disease from 9/2017 to 8/2022. The CN, SVN, IVN and facial nerve (FN) diameters and cross-sectional areas (CSA) were measured on T2-weighted sequences whilst EH was evaluated on delayed post-gadolinium MRI. Absolute nerve calibre (and that relative to the FN) in unilateral definite MD ears (2015 Barany criteria) was compared to that in both asymptomatic contralateral ears and clinical control ears. Nerve calibre in ears with severe cochlear and vestibular EH was compared to ears without EH. t tests or Wilcoxon signed-rank test/Mann–Whitney U test were applied (p < 0.001).

Results
173 patients (mean age 51.3 ± 15.1, 65 men) with 84 MD (62 unilateral) and 62 clinical control ears were studied. Absolute and relative CN dimensions were decreased in both MD ears (CSA and diameter) and the contralateral asymptomatic ears (CSA) when compared to clinical controls (p < 0.001). Absolute nerve dimensions were reduced in both severe vestibular EH (CN, IVN and SVN) and severe cochlear EH (CN) (p < 0.001), however this was not evident when adjusted according to facial nerve calibre.

Conclusion
There is decreased absolute CN calibre in both symptomatic and asymptomatic MD ears as well as ears with severe cochlear and vestibular EH on MRI.
Post-mortem to ante-mortem facial image comparison for deceased migrant identification
Authors: Wilkinson Caroline , Pizzolato Martina , De Angelis Danilo , Mazzarelli Debora , D’Apuzzo Annalisa , Liu Jessica Ching , Poppa Pasquale , Cattaneo Cristina 
Published: August 2024

AbstractThe identification of deceased migrants is a global challenge that is exacerbated by migration distance, post-mortem conditions, access to ante-mortem data for comparison, inconsistent international procedures and lack of communication between arrival and origin countries. Due to low technology requirements, fast speed analysis and ease of transferring digital data, facial image comparison is particularly beneficial in those contexts, especially in challenging scenarios when this may be the only initial ante-mortem data available to identify the deceased. The Facial Identification Scientific Working Group (FISWG) professional guidelines for facial image comparison were developed for living facial appearance, and, therefore, a tailored protocol for the application of post-mortem to ante-mortem facial image comparison was proposed and evaluated in this research. The protocol was investigated via an inter-observer and an accuracy study, using 29 forensic cases (2001–2020) from the University of Milan, provided by the Laboratory of Forensic Anthropology and Odontology. In order to replicate a migrant identification scenario, each post-mortem subject was compared to all 29 ante-mortem targets (841 comparisons). The protocol guided the practitioner through stages of facial image comparison, from broad (phase 1) to more detailed (phase 3), eventually leading to a decision of ‘exclusion’ or ‘potential match’ for each post-mortem to ante-mortem case (phase 4). In phase 4, a support scale was also utilised to indicate the level of confidence in a potential match. Each post-mortem subject could be recorded with multiple potential matches. The protocol proved to be useful guide for facial image comparison, especially for less experienced practitioners and the inter-observer study suggested good reproducibility. The majority (82–96%) of ante-mortem subjects were excluded at the first stage of the protocol, and 71 full post-mortem to ante-mortem facial image comparisons were carried out. On average, two or three potential matches were recorded for each post-mortem subject. The overall accuracy rate was 85%, with the majority (79%) of ante-mortem non-targets correctly excluded from the identification process. An increased number and quality of available ante-mortem images produced more successful matches with higher levels of support. All potential matches involving non-targets received low levels of support, and for 73% of the post-mortem subjects, the ante-mortem target was the only recorded potential match. However, two ante-mortem targets were incorrectly excluded (one at the first stage of the protocol) and therefore changes to the protocol were implemented to mitigate these errors. A full protocol and a practical recording chart for practitioner use is included with this paper.
Specific clinical and radiological characteristics of anti-NMDA receptor autoimmune encephalitis following herpes encephalitis
Authors: Dumez Pauline , Villagrán-García Macarena , Bani-Sadr Alexandre , Benaiteau Marie , Peter Elise , Farina Antonio , Picard Géraldine , Rogemond Véronique , Ruitton-Allinieu Marie-Camille , Cotton François , Aubart Mélodie , Hully Marie , Antoine Jean-Christophe , Joubert Bastien , Honnorat Jérôme 
Published: August 2024

Abstract
Background
Herpes simplex virus encephalitis (HSE) frequently triggers secondary anti-N-methyl-d-aspartate receptor encephalitis (NMDARE), but markers predicting the occurrence of this entity (HSE-NMDARE) are lacking.

Methods
We conducted a retrospective description of patients with HSE-NMDARE diagnosed between July 2014 and August 2022 and compared them to both patients with regular forms of HSE and NMDARE.

Results
Among the 375 patients with NMDARE, 13 HSE-NMDARE were included. The median age was 19 years (0.5–73), 4/13 (31%) were children < 4 years old, and 7/13 (54%) were male. The median time between HSE and NMDARE onset was 30 days (21–46). During NMDARE, symptoms differed from HSE, including increased behavioral changes (92% vs 23%, p = 0.008), movements disorders (62% vs 0%, p = 0.013), and dysautonomia (54% vs 0%, p = 0.041). Compared to 21 patients with regular HSE, patients with HSE-NMDARE more often achieved severity-associated criteria on initial MRIs, with extensive lesions (11/11, 100% vs 10/21, 48%, p = 0.005) and bilateral diffusion-weighted imaging sequence abnormalities (9/10, 90% vs 6/21, 29%, p = 0.002). Compared to 198 patients with regular NMDARE, patients with HSE-NMDARE were more frequently males (7/13, 54% vs 43/198, 22%; p = 0.015) and children < 4 (4/13, 31% vs 14/198, 7%; p = 0.016), with a worse 12-month mRS (2[1–6] vs 1[0–6], p = 0.023).

Conclusions
Herein, patients with HSE-NMDARE have a poorer long-term prognosis than patients with regular NMDARE. We report a greater rate of severity-associated criteria on initial MRIs for HSE-NMDARE compared to regular HSE, which may help identify patients with higher risk of HSE-NMDARE.
Assessment of ventilatory functions and associated inflammatory markers among workers in slaughterhouses
Authors: Ramadan Mona Abdallah , Mohammed Rateba said , Safwat Saif Eldin Aisha 
Published: August 2024

Abstract
Objective
Meat processing is among the most extensive industries globally. However, data on the effects of occupational exposure on the pulmonary health of slaughterhouse workers is limited. Ascertaining the impact of the slaughterhouse atmosphere on the breathing habits of laborers exposed to it and the inflammatory markers associated with it was the aim of the current investigation.

Methods
A cross-sectional study was performed on 82 non-smoker subjects of 41 male workers working in one of the major slaughterhouses in Cairo, Egypt, matched to 41 controls of administrative personnel. An elaborate questionnaire encompassing medical and occupational history was administered to each participant in the research. General and local systemic examinations and ventilatory function tests were carried out, and serum levels of interleukin 6 (IL-6) and high-sensitivity C-reactive protein (hsCRP) were measured.

Results
Respiratory symptoms were more prevalent with a statistically significant decline in ventilatory function parameters (FVC%, FEV1%, FEV1/FVC, FEF 25%, FEF 50%, FEF 75%, and PEF%) among the exposed group compared to those of control. In addition, there was a significantly higher serum level of inflammatory markers (IL-6 and hsCRP) among the exposed group compared to the control group, with a negative correlation with ventilatory functions. Moreover, there was a positive association between levels of serum IL-6 and hsCRP and the age and duration of employment of workers.

Conclusion
There was a notable increase in the prevalence of respiratory disorders and inflammatory markers among slaughterhouse workers. Additionally, there was a substantial decrease in ventilatory function parameters, which could be attributed to the bioaerosols they encountered in the workplace.
BK channels promote action potential repolarization in skeletal muscle but contribute little to myotonia
Authors: Dupont Chris , Blake Brianna , Voss Andrew A. , Rich Mark M. 
Published: August 2024

AbstractPatients with myotonia congenita suffer from slowed relaxation of muscle (myotonia), due to hyperexcitability caused by loss-of-function mutations in the ClC-1 chloride channel. A recent study suggested that block of large-conductance voltage- and Ca2+- activated K+ channels (BK) may be effective as therapy. The mechanism underlying efficacy was suggested to be lessening of the depolarizing effect of build-up of K+ in t-tubules of muscle during repetitive firing. BK channels are widely expressed in the nervous system and have been shown to play a central role in regulation of excitability, but their contribution to muscle excitability has not been determined. We performed intracellular recordings as well as force measurements in both wild type and BK−/− mouse extensor digitorum longus muscles. Action potential width was increased in BK−/− muscle due to slowing of repolarization, consistent with the possibility K+ build-up in t-tubules is lessened by block of BK channels in myotonic muscle. However, there was no difference in the severity of myotonia triggered by block of muscle Cl− channels with 9-anthracenecarboxylic acid (9AC) in wild type and BK−/− muscle fibers. Further study revealed no difference in the interspike membrane potential during repetitive firing suggesting there was no reduction in K+ build-up in t-tubules of BK−/− muscle. Force recordings following block of muscle Cl− channels demonstrated little reduction in myotonia in BK−/− muscle. In contrast, the current standard of care, mexiletine, significantly reduced myotonia. Our data suggest BK channels regulate muscle excitability, but are not an attractive target for therapy of myotonia.