bluuebunny/crossref_metadata_2025_split huggingface dataset:
Geomorphological analysis of the Antinaco‐Los Colorados valley, La Rioja province, Argentina
Authors: Corbat María Cecilia , Fucks Enrique , Juárez Oscar , Perdomo Santiago , Kruse Eduardo 
Published: July 2024

AbstractThe Antinaco‐Los Colorados valley (ALCV) is a tectonic depression located in the centre‐north of the province of La Rioja (Argentina), limited to both the east and west by mountain ranges, in the broken foreland region. Geomorphological research on environmental dynamics is important for both building a reference framework for further studies and for the development of the socio‐economic activities in the area. This study presents the main geomorphological features of the tectonic depression at the regional scale in order to identify the primary factors involved in its evolution and the landforms it contains. The ALCV is asymmetric, and it is filled by up to 1600 m of sediments along the western margin. Using literature, images, digital elevation models of the study area and field work, different morphologies were identified in the valley, mostly linked to Quaternary climatic and tectonic changes. These morphologies were grouped into three main morphogenetic units that characterize this landscape: the relict piedmont levels, the current piedmont and the fluvial‐aeolian plain. The identification of fluvial forms suggests that fluvial systems have been important during the evolution of the landscape. Aeolian accumulation features, currently mostly vegetated, were likely formed under drier climatic conditions than those at present and probably related to the last ice age or even more recent times. Successive reactivations of the overall system are not only tectonic, as evidenced by the structural lineaments that affect relict piedmont levels and the fluvial‐aeolian plain, but also climatic. Thus, the identified landforms suggest that climatic and tectonic variables account for the variations in the environment of the ALCV, affecting the reaccommodation of the exogenous geomorphological processes and the modelling of the relief.
Dairy milk: There are alternatives but no equivalents
Authors: Beckett Emma L. , Cassettari Tim , Starck Carlene , Fayet‐Moore Flávia 
Published: July 2024

AbstractDairy milk is a core food in many food‐based guides to healthy eating. However, plant‐based milk alternatives are becoming increasingly available as substitutes. While these products serve a subset of the population unable or unwilling to consume milk, plant‐based milk alternatives can be perceived by consumers as direct equivalents, or even more healthful alternatives to dairy milk. This commentary addresses the significant differences in nutrient content that may have implications for the intake of key nutrients in the case of direct substitutions. Furthermore, while there is a significant body of knowledge demonstrating the significant health benefits associated with dairy milk consumption and a small number of potentially negative associations, there is a paucity of data on the health benefits of plant‐based milk alternatives directly. A “health halo” may exist based on matching individual nutrients through fortification, lower energy levels, and the health properties of the unprocessed raw characterizing ingredients of plant‐based milk alternatives. This may mislead consumers regarding healthfulness. Similarly, environmental attributes based on volumes of production, without considering contribution to nutrients, may also skew consumer perception. Positioning of plant‐based milk alternatives in food‐based dietary guidelines, marketing, and personal recommendations should acknowledge the differences in nutritional, bioactive, and health properties between plant‐based milk alternatives and dairy milk to ensure appropriate adaptations are made to account for shortfalls in nutrients.
Utilizing chia flour‐based gelled emulsion for the development of functional beef patties with enhanced nutritional profile
Authors: Serdaroğlu Meltem , Yüncü‐Boyacı Özlem , Kavuşan Hülya Serpil 
Published: July 2024

AbstractThis study evaluated chia flour, egg white powder, and peanut oil gelled emulsion (GE) as a fat replacer in beef patties. Four formulations were prepared, replacing beef fat with different levels of gelled emulsion: 0% (C), 50% (G50), 75% (G75), and 100% (G100). The beef patties with GE showed improved nutritional properties, technological parameters, and cooking characteristics. A remarkable reduction in SFAs was achieved with the substitution of beef fat by the GE, with reductions of 33.71%, 46.64%, and 72.04% for 50%, 75%, and 100% substitution levels, respectively. AI and TI indices decreased, indicating healthier profiles. Reformulated samples exhibited lower hardness, gumminess, and chewiness values. Color and appearance were similar to the control, with higher sensory scores for G75 and G100. GE impacted color parameters, increasing L* and b* values. The utilization of GE effectively minimized voids in the beef patty structure, leading to improved cooking yield and a more compact structure. GE influenced oxidative stability, with average onset temperatures of 126.33°C (50% GE), 140.58°C (75% GE), and 127.04°C (100% GE). In conclusion, gelled emulsions could successfully contribute to producing healthier meat products.
Extranodal marginal zone lymphoma of the larynx: A case report and scoping review
Authors: Werner Michael T. , Cooper Dylan J. , Kaplan Seth E. 
Published: July 2024

AbstractBackgroundThis scoping review aims to review cases of extranodal marginal zone lymphoma (MZL) of the larynx to establish best management practices for this rare clinical entity.MethodsIn this paper, we report a case of laryngeal MZL, in accordance with CARE guidelines. We then performed a scoping review according to PRISMA‐ScR criteria of published cases of MZL involving the larynx. The following data were collected for each case: age, sex, size, location(s) involved, stage, treatment, follow‐up, and recurrence duration.ResultsSixty‐six patients with laryngeal MZL, first reported in 1990, were identified. Characterized by its low‐grade histological appearance and indolent course, laryngeal MZL is generally confined to the larynx and has an excellent prognosis with radiation used as first‐line therapy.ConclusionsIt is imperative for clinicians to consider lymphoma in the differential diagnosis of a laryngeal tumor from any subsite, as certain pathologies may carry high risks of metastasis.
Potential mechanisms and targeting strategies of the gut microbiota in antitumor immunity and immunotherapy
Authors: Yin Qian , Ni Jiao‐jiao , Ying Jie‐er 
Published: July 2024

AbstractBackgroundImmunotherapies, notably immune checkpoints inhibitors that target programmed death 1/programmed death ligand 1(PD‐1/PD‐L1) and cytotoxic T lymphocyte‐associated antigen 4 (CTLA‐4), had profoundly changed the way advanced and metastatic cancers are treated and dramatically improved overall and progression‐free survival.AimsThis review article aimed to explore the underlying molecular mechanisms by which the gut microbiota affects antitumor immunity and the efficacy of cancer immunotherapy.MethodsWe summarized the latest knowledge supporting the associations among the gut microbiota, antitumor immunity, and immunotherapy. Moreover, we disscussed the therapeutic strategy for improving immunotherapy efficacy by modulating gut microbiota in cancer treatment.ResultsThe potential molecular mechanisms underlying these associations are explained in terms of four aspects: immunomodulation, molecular mimicry, mamps, and microbial metabolites.ConclusionThe gut microbiota significantly impacts antitumor immunity and alters the effectiveness of cancer immunotherapy.
Anatomical‐based classification of dorsolateral parametrectomy for deep endometriosis. Correlation with surgical complications and functional outcomes: A single‐ center prospective study
Authors: Ianieri Manuel Maria , Alesi Maria Vittoria , Querleu Denis , Ercoli Alfredo , Chiantera Vito , Carcagnì Antonella , Campolo Federica , Greco Pierfrancesco , Scambia Giovanni 
Published: July 2024

AbstractObjectiveTo evaluate complication rate and functional outcomes of nerve‐sparing parametrectomy for deep endometriosis in relation to the extension of the surgical procedure, based on recognizable anatomical landmarks.MethodsThis was a prospective single‐center study including all patients undergoing parametrectomy for deep endometriosis from September 2020 to June 2023 at our tertiary center. Dorsolateral parametrectomies were divided into parametrectomies medial to the presacral fascia and cranial to the medial rectal artery (superficial parametrectomy), and parametrectomies in which one of the two landmarks was overcome during the surgical procedure, leading to the excision of tissue lateral to the presacral fascia (deep parametrectomy type 1, or DP1) or caudal to the medial rectal artery (DP2). Finally, we used the hypogastric fascia as landmark to define type 3 deep parametrectomy (DP3), when the procedure was deeply lateral to the fascia.ResultsBladder voiding deficit occurred in 9.7% of cases, with higher rates in DP2 (20.8%) and DP3 (30%) groups. Regarding postoperative gastrointestinal function, our data showed a significant improvement over time in all groups, with the exception of DP2; instead an improvement in postoperative bladder function was only shown in DP3. Parametrectomy was not associated with a simultaneous improvement in sexual function expressed with the female sexual function index, in any of the four groups.ConclusionOur classification constitutes a concrete approach for comparing, in a standardized way, the complications and functional outcomes of parametrectomy, which, even if carried out by expert surgeons, demonstrates a non‐negligible rate of bladder voiding deficit.
Safety and efficacy of motor imagery‐based physical activity in high‐risk pregnancy: A randomized controlled study
Authors: Yakıt Yeşilyurt Seda , Birinci Olgun Tansu , Ayaz Taş Seda , Tosun Gökhan , Özer Mehmet , Özengin Nuriye 
Published: July 2024

AbstractObjectiveThis study aimed to investigate the acute effects of motor imagery‐based physical activity on maternal well‐being, maternal blood pressure, heart rate, oxygen saturation, fetal heart rate, and uterine contractions in women with high‐risk pregnancies.MethodsThis randomized controlled trial was conducted in Izmir Tepecik Education and Research Hospital from August 2023 to January 2024. Seventy‐six women with high‐risk pregnancies were randomized into two groups: a motor imagery group (n = 38, diaphragmatic‐breathing exercise and motor imagery‐based physical activity) and a control group (n = 38, diaphragmatic‐breathing exercise). Maternal well‐being was determined using the Numerical Rating Scale‐11. Digital sphygmomanometry was used to measure maternal heart rate and blood pressure, pulse oximetry for oxygen saturation, and cardiotocography for fetal heart rate and uterine contractions. Assessments were performed pre‐intervention, mid‐intervention, and post‐intervention.ResultsThere were no significant differences in baseline characteristics between groups (P > 0.05). There was a significant main effect of time in terms of maternal well‐being and maternal heart rate (P = 0.001 and P = 0.015). In addition, there was a significant main effect of the group on oxygen saturation (P = 0.025). The overall group‐by‐time interaction was significant for maternal well‐beingm with an effect size of 0.05 (P = 0.041).ConclusionThe combination of diaphragmatic‐breathing exercises and a motor imagery‐based physical activity program in women with high‐risk pregnancies was determined to have no adverse effects on the fetus, did not induce uterine contractions, and resulted in a significant improvement in maternal well‐being and oxygen saturation. Thus, imagery‐based physical activity can be used in high‐risk pregnancies where physical activity and exercise are not recommended.
Retinal Blood Vessels Segmentation With Improved SE‐UNet Model
Authors: Wan Yibo , Wei Gaofeng , Li Renxing , Xiang Yifan , Yin Dechao , Yang Minglei , Gong Deren , Chen Jiangang 
Published: July 2024

ABSTRACTAccurate segmentation of retinal vessels is crucial for the early diagnosis and treatment of eye diseases, for example, diabetic retinopathy, glaucoma, and macular degeneration. Due to the intricate structure of retinal vessels, it is essential to extract their features with precision for the semantic segmentation of medical images. In this study, an improved deep learning neural network was developed with a focus on feature extraction based on the U‐Net structure. The enhanced U‐Net combines the architecture of convolutional neural networks (CNNs) with SE blocks (squeeze‐and‐excitation blocks) to adaptively extract image features after each U‐Net encoder's convolution. This approach aids in suppressing nonvascular regions and highlighting features for specific segmentation tasks. The proposed method was trained and tested on the DRIVECHASE_DB1 and STARE datasets. As a result, the proposed model had an algorithmic accuracy, sensitivity, specificity, Dice coefficient (Dc), and Matthews correlation coefficient (MCC) of 95.62/0.9853/0.9652, 0.7751/0.7976/0.7773, 0.9832/0.8567/0.9865, 82.53/87.23/83.42, and 0.7823/0.7987/0.8345, respectively, outperforming previous methods, including UNet++, attention U‐Net, and ResUNet. The experimental results demonstrated that the proposed method improved the retinal vessel segmentation performance.
Using plasma products in small animal practice
Authors: Allcock Lauren , Hagley Simon 
Published: July 2024

Background: A variety of plasma products are commercially available for veterinary use in the UK. These products have a wide array of beneficial properties and can be considered for use in multiple clinical scenarios. Although a large proportion of the available information surrounding their use is gathered from human scientific data, recent veterinary studies have provided new evidence for their safe administration in veterinary patients.Aim of the article: This article provides a detailed view of fresh frozen plasma and offers readers an easy‐to‐digest guide on how to use it in practice. It describes some of the recent evidence supporting fresh frozen plasma use, allowing readers to evaluate whether administration is indicated in their patients. Finally, the article briefly summarises other plasma products available for veterinary use in the UK.
Females and Housing First: An analysis of 18‐month outcomes in a randomized controlled trial
Authors: Isaak Corinne A. , Nelson Geoffrey , Roebuck Maryann , Aubry Tim , Macnaughton Eric , Kirst Maritt , O'Campo Patricia , Woodhall‐Melnik Julia , Agha Ayda , Faruquzzaman Oeishi , Purcell Sarah 
Published: July 2024

AbstractThe main objective of this research was to qualitatively examine the impacts of Housing First (HF) specifically on those participants who identified themselves as female in response to question asking what their gender was. The data analyzed are from a larger, muti‐site, randomized controlled trial. χ2 analysis was used to compare the life changes (coded as positive, neutral, or negative) experienced by 64 females (42 HF and 22 TAU). An in‐depth qualitative analysis was conducted on 45 of these participants (23 HF and 22 TAU). Significantly more female HF participants reported making positive life changes from baseline to 18‐month than those in TAU. Relative to females in TAU, female HF participants reported a number of specific positive changes, including enhanced safety, improved recovery in mental illness, greater reductions in drug use, and individual changes. The implications of findings for strengthening HF programs to meet the unique needs of female participants are discussed.
Changes in risk behaviour following a network peer education intervention for HIV prevention among male Tajik migrants who inject drugs in Moscow: a cluster‐randomized controlled trial
Authors: Mackesy‐Amiti Mary Ellen , Bahromov Mahbatsho , Levy Judith A. , Jonbekov Jonbek , Luc Casey M. 
Published: July 2024

AbstractIntroductionThe “Migrants’ Approached Self‐Learning Intervention in HIV/AIDS for Tajiks” (MASLIHAT) recruits and trains Tajik labour migrants who inject drugs as peer educators (PEs) in delivering HIV prevention information and encouragement to adopt risk‐reduction norms and practices within their diaspora social networks while reducing their own HIV risk.MethodsThe MASLIHAT intervention was tested in Moscow in a cluster‐randomized controlled trial with 12 recruitment sites assigned to either the MASLIHAT intervention or an equal‐time peer‐educator training focused on other health conditions (TANSIHAT). From October 2021 to April 2022, 140 male Tajik migrants who inject drugs were recruited as PEs to attend the 5‐session MASLIHAT training or the TANSIHAT non‐HIV comparison condition. Each participant in both groups recruited two network members (NMs) who inject drugs with the intent to share with them the information and positive strategies for change they had learned (n = 280). All PEs and NMs (n = 420) participated in baseline and follow‐up interviews at 3‐month intervals for 1 year. All received HIV counselling and testing. Modified mixed effects Poisson regressions tested for group differences in injection practices, sexual risk behaviours and heavy alcohol use over time.ResultsAt baseline, across both groups, 75% of participants reported receptive syringe sharing (RSS), 42% reported condomless sex and 20% reported binge drinking at least once a month. In contrast to TANSIHAT where HIV risk behaviours remained the same, significant intervention effects that were sustained over the 12 months were observed for receptive syringe and ancillary equipment sharing among both MASLIHAT PEs and NMs (p < 0.0001). Significant declines in the prevalence of sexual risk behaviours were also associated with the MASLIHAT intervention (p < 0.01), but not the comparison condition. Binge alcohol use was not affected in either condition; the MASLIHAT intervention had a transitory effect on drinking frequency that dissipated after 9 months.ConclusionsThe MASLIHAT peer‐education intervention proved highly effective in reducing HIV‐related injection risk behaviour, and moderately effective in reducing sexual risk behaviour among both PEs and NMs. Network‐based peer education is an important tool for HIV prevention among people who inject drugs, especially in environments that are not amenable to community‐based harm reduction.
Fast screening of α‐glucosidase inhibitors from Ginkgo biloba leaf by using α‐glucosidase immobilized on magnetic metal‐organic framework
Authors: Li Yue , Liu Hongmei , Wang Sikai , Fang Wei , Jiang Xinxin , Zhang Guoqi , Zhao Yan 
Published: July 2024

In this study, a ligand fishing method for the screening of α‐glucosidase inhibitors from Ginkgo biloba leaf was established for the first time using α‐glucosidase immobilized on the magnetic metal‐organic framework. The immobilized α‐glucosidase exhibited enhanced resistance to temperature and pH, as well as good thermal stability and reusability. Two ligands, namely quercitrin and quercetin, were screened from Ginkgo biloba leaf and identified by ultra‐high performance liquid chromatography‐tandem mass spectrometry. The half‐maximal inhibitory concentration values for quercitrin and quercetin were determined to be 105.69 ± 0.39 and 83.49 ± 0.79 µM, respectively. Molecular docking further confirmed the strong inhibitory effect of these two ligands. The proposed approach in this study demonstrates exceptional efficiency in the screening of α‐glucosidase inhibitors from complex natural medicinal plants, thus exhibiting significant potential for the discovery of antidiabetic compounds.
A low SLL series‐fed patch array antenna using simple and compact ridge waveguide‐based unequal feeding network
Authors: Chen Zhi Xing , Farahbakhsh Ali , Li Ze Hao , Su Huafeng , Zhang Xiu Yin 
Published: July 2024

AbstractIn this paper, the design of a low sidelobe level (SLL) 10 × 10‐element series‐fed patch antenna array is presented. A ridge waveguide‐based nonuniform feeding layer is employed to excite the array. Each column of the antenna array includes a tapered 10‐element series fed patch antenna array. By using a simple and compact center‐fed ridge waveguide, a low loss feeding layer is achieved. The coupling between the ridge waveguide and the standard WR‐75 flange is performed by employing a proposed stepped transition. The measured results indicate that the maximum gain is 24.1 dBi and the SLL is lower than −20 dB in both H‐ and E‐planes at 12.7 GHz. The proposed low SLL planar series‐fed patch antenna array can be utilized as an acceptable candidate for radar applications.
Optimal short carbon fiber‐reinforced polyamide 6 composites with lifted high strength and toughness for fused filament fabrication
Authors: Zhang Jianfang , Dong Weiping , Li Xiping , Wei Yicheng , Hu Zhonglue , Shiju E. , Zheng Jiajia , Chen Hongxuan , Wang Sisi 
Published: July 2024

AbstractThe high‐strength and lightweight carbon fiber‐reinforced composites are widely used in various industries. Fused Filament Fabrication (FFF), the most cost‐effective Additive Manufacturing (AM) technology, has gained significant application advantages in the industry. The objective of this study is to improve the toughness of the carbon fiber‐reinforced polyamide composites used for FFF. In this work, HDPE was selected to reduce the hygroscopicity of PA6 while lowering the cost, carbon fiber was introduced to reinforce the PA6/HDPE blend. The elastomer POE‐g‐MAH was applied to increase the toughness of the composites as well as to improve the compatibility of the incompatible system of PA6/HDPE. Mechanical tests and micromorphology observation were carried on the FFF printed samples. The test results show that when 20 phr POE‐g‐MAH was added, optimum mechanical properties were obtained for the composites with about 18.9 wt% carbon fiber content. The tensile strength reached 94.1 MPa, and the notched impact strength reached 21.0 kJ/m2, which were 180.8% and 610.7% higher than that of the neat PA6, respectively. It is applicable for various applications that require high‐impact strength, including automotive parts and some machine components.Highlights
The PA‐2CF‐C20 composite exhibits high strength and high toughness, the tensile strength reaches 94.1 MPa and the notched impact strength reaches 21.0 kJ/m2.
Successfully prepared cost‐effective and high‐performance filament for FFF 3D printers.