bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Selective O‐Difluoromethylation of 1,3‐Diones by Bromodifluoromethylating Reagents.
Authors: Liu Guokai , Wang Xin , Xu Xiu‐Hua , Lu Xu , Tokunaga Etsuko , Tsuzuki Seiji , Shibata Norio 
Published: July 2013

AbstractThe reaction of in‐situ generated difluorocarbene from (I) with 1,3‐diones leads to the formation of a wide variety of difluoromethyl enol ethers in good to excellent yields.
ChemInform Abstract: Ruthenium(II)‐Catalyzed Regioselective Reductive Coupling of α‐Imino Esters with Dienes.
Authors: Zhu Shujie , Lu Xiaoxia , Luo Yueting , Zhang Wei , Jiang Huanfeng , Yan Ming , Zeng Wei 
Published: July 2013

AbstractA novel reductive coupling reaction between N‐aryl‐α‐imino esters and dienes is developed.
ChemInform Abstract: Reaction of Organozinc Halides with Aryl Isocyanates.
Authors: Yang Haoran , Huang Danfeng , Wang Ke‐Hu , Xu Changming , Niu Teng , Hu Yulai 
Published: July 2013

AbstractThe title reaction provides a mild alternative method for the synthesis of N‐substituted carbamates or amides.
ChemInform Abstract: Asymmetric Synthesis of β‐Amino Nitriles Through a ScIII‐Catalyzed Three‐Component Mannich Reaction of Silyl Ketene Imines.
Authors: Zhao Jiannan , Liu Xiaohua , Luo Weiwei , Xie Mingsheng , Lin Lili , Feng Xiaoming 
Published: July 2013

AbstractA new catalyst system allows the diastereo‐ and enantioselective synthesis of various title compounds, precursors of optically active diamines and β‐amino acids.
ChemInform Abstract: A Catalytic Approach for the Synthesis of Allylic Azides from Aryl Vinyl Carbinols.
Authors: Srinu G. , Srihari P. 
Published: July 2013

AbstractTreatment of aryl vinyl carbinols with TmsN3 under conditions A) results in formation of unexpected allylic azides, accompanied by lower amounts of disilylated by‐products such as (III).
ChemInform Abstract: Enantioselective Additions of Aryltitanium Tris(isopropoxide) to Ketones: Structure of [(i‐PrO)2Ti{μ‐(S)‐BINOLate}(μ‐O‐i‐Pr)TiPh (O‐i‐Pr)2], Study of Mechanistic and Stereochemical Insights.
Authors: Wu Kuo‐Hui , Kuo Yi‐Yin , Chen Chien‐An , Huang Yi‐Ling , Gau Han‐Mou 
Published: July 2013

AbstractThe simple title reaction affords a wide range of different substituted tertiary alcohols.
ChemInform Abstract: Synthesis of Novel Aryl and Heteroaryl Acyl Sulfonimidamides via Pd‐Catalyzed Carbonylation Using a Nongaseous Precursor.
Authors: Borhade Sanjay R. , Sandstroem Anja , Arvidsson Per I. 
Published: July 2013

AbstractThis novel methodology, employing sulfonimidamides as nucleophiles and CO gas released in situ from solid Mo(CO)6 in a sealed two‐chamber system, shows high functional group tolerance affording a wide range of carbamate protected sulfonimidamides in good to excellent yields.
ChemInform Abstract: A New Application of Rhodanine as a Green Sulfur Transferring Agent for a Clean Functional Group Interconversion of Amide to Thioamide Using Reusable MCM‐41 Mesoporous Silica.
Authors: Ray Suman , Bhaumik Asim , Dutta Arghya , Butcher Ray J. , Mukhopadhyay Chhanda 
Published: July 2013

AbstractThe novel protocol allows the thiolation of amides, ureas, and ketones to produce essential building blocks for sulfur‐containing systems.
ChemInform Abstract: Highly Efficient Knoevenagel Condensation Reactions Catalyzed by a Proline‐Functionalized Polyacrylonitrile Fiber.
Authors: Li Guo‐Wei , Xiao Jia , Zhang Wen‐Qin 
Published: July 2013

AbstractPFAF is a highly efficient catalyst for the condensation of aromatic aldehydes and ethyl cyanoacetate or malononitrile.
ChemInform Abstract: Rhodium(III)‐Catalyzed C(sp2)—H Activation and Electrophilic Amidation with N‐Fluorobenzenesulfonimide.
Authors: Tang Ren‐Jin , Luo Cui‐Ping , Yang Luo , Li Chao‐Jun 
Published: July 2013

AbstractThe reaction requires only catalytic amount of a base and proceeds under oxidant‐free conditions.
ChemInform Abstract: Planar Chiral Triazole‐Based Phosphanes Derived from [2.2]Paracyclophane and Their Activity in Suzuki Coupling Reactions.
Authors: Glover Jean E. , Martin David J. , Plieger Paul G. , Rowlands Gareth J. 
Published: July 2013

AbstractFour cyclophane derivatives with triazole‐phosphane moieties are synthesized and tested as ligands in Suzuki cross‐coupling reactions with compound (V) giving the best results.
ChemInform Abstract: An Asymmetric Organocatalytic Quadruple Cascade Initiated by a Friedel—Crafts‐Type Reaction with Electron‐Rich Arenes.
Authors: Erdmann Nico , Philipps Arne R. , Atodiresei Iuliana , Enders Dieter 
Published: July 2013

AbstractThe reaction involves up to three different Michael acceptors and leads to the highly substituted cyclohexenecarbaldehydes generating up to four contiguous stereocenters.
ChemInform Abstract: Organocatalytic Asymmetric Michael Addition/Carbon—Carbon Bond Cleavage of Trifluoromethyl α‐Fluorinated gem‐Diols to Nitroolefins.
Authors: Saidalimu Ibrayim , Fang Xiang , Lv Wenwen , Yang Xueyan , He Xiaopeng , Zhang Jingyuan , Wu Fanhong 
Published: July 2013

AbstractLow yields and diastereoselectivity is observed for the substrates bearing aliphatic substituents.
ChemInform Abstract: Modular Access to 9,9‐Spirobifluorenes by Oxidative Coupling Using Molybdenum Pentachloride.
Authors: Trosien Simon , Schollmeyer Dieter , Waldvogel Siegfried R. 
Published: July 2013

AbstractThe reactions of diarylfluorenes and substrates (III) or (V) result in formation of spirobifluorenes and fluorene derivatives.
ChemInform Abstract: Construction of spiro‐Tetrahydroquinolines via Intramolecular Dearomatization of Quinolines: Free of a Preinstalled Activation Group.
Authors: Wang Shou‐Guo , Zhang Wei , You Shu‐Li 
Published: July 2013

AbstractAn efficient synthesis of spiro‐tetrahydroquinolines is realized via an acid‐catalyzed cascade reaction consisting of hydrogenative dearomatization followed by intramolecular aza‐Friedel—Crafts alkylation.
ChemInform Abstract: Chiral Quaternary Ammonium Aryloxide/N,O‐Bis(trimethylsilyl)acetamide Combination as Efficient Organocatalytic System for the Direct Vinylogous Aldol Reaction of (5H)‐Furan‐2‐one Derivatives.
Authors: Claraz Aurelie , Oudeyer Sylvain , Levacher Vincent 
Published: July 2013

AbstractThe reaction proceeds with various aromatic and aliphatic aldehydes with moderate dia‐ and high enantioselectivities.
ChemInform Abstract: Using Conveniently Designed α‐Amino Ketones in Michael Reactions under Iminium Catalysis: Enantioselective Synthesis of γ‐Lactams and γ‐Amino‐δ‐keto Esters.
Authors: Talavera Garazi , Reyes Efraim , Vicario Jose L. , Carrillo Luisa , Uria Uxue 
Published: July 2013

AbstractThe reaction of α,β‐unsaturated aldehydes with N‐tosylaminoacetophenone (II) proceeds with moderate cis‐selectivity but both diastereomers are obtained with high enantioselectivity.
ChemInform Abstract: Umpolung of Hemiaminals: Titanocene‐Catalyzed Dehydroxylative Radical Coupling Reactions with Activated Alkenes.
Authors: Zheng Xiao , Dai Xi‐Jie , Yuan Hong‐Qiu , Ye Chen‐Xi , Ma Jie , Huang Pei‐Qiang 
Published: July 2013

AbstractThe novel method uses the TiCl2(Cp)2/Mg/TmsCl catalytic reduction system.
ChemInform Abstract: Enantioselective Synthesis of Succinimides by Michael Addition of 1,3‐Dicarbonyl Compounds to Maleimides Catalyzed by a Chiral Bis(2‐aminobenzimidazole) Organocatalyst.
Authors: Gomez‐Torres Eduardo , Alonso Diego A. , Gomez‐Bengoa Enrique , Najera Carmen 
Published: July 2013

AbstractA full and detailed account on previously published studies is presented.
ChemInform Abstract: Mitsunobu Cyclodehydration of N‐Pivaloyl‐2‐aminophenethyl Alcohol for Asymmetric Synthesis of trans‐2,3‐Disubstituted Indolines.
Authors: Kang Kyoung Hee , Kim Yelim , Im Chan , Park Yong Sun 
Published: July 2013

AbstractThe access to the other enantiomer can be easily achieved by using (+)‐sparteine.
ChemInform Abstract: Asymmetric Aza‐Michael Additions of 4‐Nitrophthalimide to Nitroalkenes and Preliminary Study of the Products for Herbicidal Activities.
Authors: Ma Shijun , Wu Lulu , Liu Ming , Huang Yaodong , Wang Yongmei 
Published: July 2013

AbstractFor the first time the highly enantioselective title reaction using a readily available chiral catalyst is developed.
ChemInform Abstract: 3‐Chlorooxindoles: Versatile Starting Materials for Asymmetric Organocatalytic Synthesis of Spirooxindoles.
Authors: Noole Artur , Oseka Maksim , Pehk Tonis , Oeeren Mario , Jaerving Ivar , Elsegood Mark R. J. , Malkov Andrei V. , Lopp Margus , Kanger Tonis 
Published: July 2013

AbstractExcellent dia‐ and enantioselectivities are observed in the reaction of 3‐chloroindoles with aromatic α,β‐unsaturated aldehydes.
ChemInform Abstract: Facile One‐Pot Synthesis of Novel Dispirooxindole‐Pyrrolidine Derivatives and Their Antimicrobial and Anticancer Activity Against A549 Human Lung Adenocarcinoma Cancer Cell Line.
Authors: Arun Y. , Bhaskar G. , Balachandran C. , Ignacimuthu S. , Perumal P. T. 
Published: July 2013

AbstractThe title compounds (IV) and (VI) are obtained via 1,3‐dipolar cycloaddition of an azomethine ylide generated from isatin and sarcosine with dipolarophiles.
ChemInform Abstract: A Photochemical Route to Benzo[a]carbazoles via Domino Elimination/Electrocyclization of 2‐Aryl‐3‐(1‐tosylalkyl)indoles.
Authors: Protti Stefano , Palmieri Alessandro , Petrini Marino , Fagnoni Maurizio , Ballini Roberto , Albini Angelo 
Published: July 2013

AbstractThe reaction can also be conducted in THF.
ChemInform Abstract: An Intriguing and Facile One‐Pot Catalytic Synthesis of N‐Alkylated Lactams.
Authors: Zoidis Grigoris , Naesens Lieve , De Clercq Erik 
Published: July 2013

AbstractThe title compounds are obtained by Raney‐nickel‐catalyzed hydrogenation of 1,2‐adamantane oxime esters or cyano esters.
ChemInform Abstract: Design, Synthesis and Neuropharmacological Activity of Dihydro Imidazole Derivatives.
Authors: Mariappan G. , Alam Sadrul , Sutharson L. , Haldar P. K. , Nath Shyamalendu 
Published: July 2013

AbstractAll the synthesized compounds (III), especially derivatives (IIIb), show effective neuropharmacological activities.
ChemInform Abstract: Intermolecular C—O Addition of Carboxylic Acids to Arynes: Synthesis of o‐Hydroxyaryl Ketones, Xanthones, 4‐Chromanones, and Flavones.
Authors: Dubrovskiy Anton V. , Larock Richard C. 
Published: July 2013

AbstractThe presented reactions are efficient and simple utilizing readily available carboxylic acids and commercially available o‐(trimethylsilyl)aryl triflates.
ChemInform Abstract: An Efficient Domino Reaction in Ionic Liquid: Synthesis and Biological Evaluation of Some Pyrano‐ and Thiopyrano‐Fused Heterocycles.
Authors: Parmar Narsidas J. , Patel Rikin A. , Parmar Bhagyashri D. , Talpada Navin P. 
Published: July 2013

AbstractA series of pyrazolopyran annulated‐pyrano‐fused coumarins (V) and thiopyrano‐fused quinolones (III) are obtained in an improved domino/Knoevenagel‐hetero‐Diels—Alder reaction of aldehydes (I) and (IV) with pyrazolones (II).
ChemInform Abstract: Palladium‐Catalyzed Oxidative Insertion of Carbon Monoxide to N‐Sulfonyl‐2‐aminobiaryls Through C—H Bond Activation: Access to Bioactive Phenanthridinone Derivatives in One Pot.
Authors: Rajeshkumar Venkatachalam , Lee Tai‐Hua , Chuang Shih‐Ching 
Published: July 2013

AbstractAn efficient Pd‐catalyzed oxidative carbonylation of N‐sulfonyl‐2‐amino‐biaryls is presented.
ChemInform Abstract: Efficient Approach to 4‐Sulfonamidoquinolines via Copper(I)‐Catalyzed Cascade Reaction of Sulfonyl Azides with Alkynyl Imines.
Authors: Cheng Guolin , Cui Xiuling 
Published: July 2013

AbstractA novel and efficient one step approach to 4‐sulfonamidoquinolines via Cu‐catalyzed reaction of alkynyl imines with sulfonyl azides is developed.
ChemInform Abstract: One‐Pot Synthesis of Allylamine Derivatives by Iodine‐Catalyzed Three‐Component Reaction of N‐Heterocycles, Paraformaldehyde and Styrenes.
Authors: Quan Zheng‐Jun , Hu Wang‐Hua , Zhang Zhang , Da Yu‐Xia , Jia Xiao‐Dong , Wang Xi‐Cun 
Published: July 2013

AbstractAn efficient reaction to the title compounds with high stereo‐ and regioselectivities is described.
ChemInform Abstract: Synthetic Studies on Compounds Related to Aminoimidazolecarboxamide: Synthesis of Angularly Fused Purine Derivatives and a Solid Phase Ring Transformation (ANRORC) to Imidazo[1,5‐a]pyrazine.
Authors: Chattopadhyay Gautam , Ray Partha Sinha 
Published: July 2013

AbstractN1‐Protected 5‐aminoimidazole‐4‐carboxamides (I) are used as convenient precursors for the synthesis of various new fused purine derivatives and imidazopyrazines (IV).
ChemInform Abstract: Expeditious Synthesis of Chiral 1,2,3,4‐Tetrahydropyrrolo[1,2‐a]pyrazines.
Authors: Bhowmik Subhendu , Kumar Anil K. S. , Batra Sanjay 
Published: July 2013

AbstractStarting from commercially available cheap raw materials including natural amino acids, a facile approach to the heterocyclic title scaffold is developed which can be subjected to hydride reduction as is demonstrated for derivatives (IIIa)‐(IIIc).
ChemInform Abstract: Synthesis of Novel Fluorine‐ and Iodine‐Containing [1,2,4]Triazolo[3,4‐b][1,3]thiazines Based 3‐(Alkenylthio)‐5‐(trifluoromethyl)‐4H‐1,2,4‐triazole‐3‐thiols.
Authors: Il'inykh Elena S. , Kim Dmitry G. , Kodess Mikhail I. , Matochkina Evgeniya G. , Slepukhin Pavel A. 
Published: July 2013

AbstractThe title compounds are obtained via alkenation reaction with different alkenyl halides.
ChemInform Abstract: A Tandem Copper (II)‐Promoted Synthesis of 2‐Substituted Pyrrolo[2,1‐f][1,2,4]triazin‐4(3H)‐ones.
Authors: Chen Yanhong , Xiang Haoyue , Tan Cun , Xie Yuyuan , Yang Chunhao 
Published: July 2013

AbstractElectron‐donating groups on both partners accelerate the reaction.
ChemInform Abstract: Selective Mono‐Arylation in Palladium‐Catalyzed Cross‐Coupling Reaction of Dichlorotriazines with Phenylboronate Ester Derivatives.
Authors: Dong Jin‐Fu , Yu Xin , Ning Cheng‐Qing , Hu Liang , Yu Nie‐Fang 
Published: July 2013

AbstractOptimized conditions are developed for the preparation of the biologically interesting phenyltriazine skeleton, suitable for further functionalization.
ChemInform Abstract: Steroidal Constituents from the Leaves of Hosta longipes and Their Inhibitory Effects on Nitric Oxide Production
Authors: Kim Chung Sub , Kim Sun Yeou , Moon Eunjung , Lee Mi Kyeong , Lee Kang Ro 
Published: July 2013

Abstractisolation, structure and inhibition of NO production of three new steroidal compounds, longipenane (Ia), longipenane 26‐O‐β‐D‐glucopyranoside (Ib) and a new trisaccharide, along with two known steroidal saponins
ChemInform Abstract: Synthesis of Chiral Amino Acid Anilides by Ligand‐Free Copper‐Catalyzed Selective N‐Arylation of Amino Acid Amides.
Authors: Dong Junyu , Wang Yan , Xiang Qinjie , Lv Xirui , Weng Wen , Zeng Qingle 
Published: July 2013

AbstractGenerally the reactivity of aryl‐/heteroaryl‐/styryl‐halides is I < Br < Cl.
ChemInform Abstract: Aspulvinones from a Mangrove Rhizosphere Soil‐Derived Fungus Aspergillus terreus Gwq‐48 with Antiinfluenza A Viral (H1N1) Activity.
Authors: Gao Huquan , Guo Wenqiang , Wang Qiang , Zhang Lianqing , Zhu Meilin , Zhu Tianjiao , Gu Qianqun , Wang Wei , Li Dehai 
Published: July 2013

AbstractA new butenolide, isoaspulvinone E (I), is isolated along with two known butenolides from the marine derived fungus, Aspergillus terreus Gwq‐48.
ChemInform Abstract: Synthesis, Characterization, and Properties of Zero‐valent Iron Nanoparticles
Authors: Baer Donald R. , Tratnyek Paul G. , Qiang You , Amonette James E. , Linehan John , Sarathy Vaishnavi , Nurmi James T. , Wang Chongmin , Antony J. 
Published: July 2013

AbstractReview: 80 refs.
ChemInform Abstract: Fluoro‐C‐glycosides and Fluoro‐Carbasugars, Hydrolytically Stable and Synthetically Challenging Glycomimetics
Authors: Leclerc Eric , Pannecoucke Xavier , Etheve‐Quelquejeu Melanie , Sollogoub Matthieu 
Published: July 2013

AbstractReview: 55 refs.
ChemInform Abstract: Microwaves in Heterocyclic Chemistry
Authors: Bazureau Jean Pierre , Paquin Ludovic , Carrie Daniel , L'Helgoual'ch Jean Martial , Guiheneuf Solene , Coulibaly Karime Wacothon , Burgy Guillaume , Komaty Sarah , Limanton Emmanuelle 
Published: July 2013

AbstractReview: 166 refs.
Clinical costs of colorectal cancer screening in 5 federally funded demonstration programs
Authors: Tangka Florence K. L. , Subramanian Sujha , Beebe Maggie C. , Hoover Sonja , Royalty Janet , Seeff Laura C. 
Published: July 2013

BACKGROUNDThe Centers for Disease Control and Prevention initiated the Colorectal Cancer Screening Demonstration Program (CRCSDP) to explore the feasibility of establishing a large‐scale colorectal cancer (CRC) screening program for underserved populations in the United States. The authors of this report assessed the clinical costs incurred at each of the 5 participating sites during the demonstration period.METHODSBy using data on payments to providers by each of the 5 CRCSDP sites, the authors estimated costs for specific clinical services and overall clinical costs for each of the 2 CRC screening methods used by the sites: colonoscopy and fecal occult blood test (FOBT).RESULTSAmong CRCSDP clients who were at average risk for CRC and for whom complete cost data were available, 2131 were screened by FOBT, and 1888 were screened by colonoscopy. The total average clinical cost per individual screened by FOBT (including costs for screening, diagnosis, initial surveillance, office visits, and associated clinical services averaged across all individuals who received screening FOBT) ranged from $48 in Nebraska to $149 in Greater Seattle. This compared with an average clinical cost per individual for all services related to the colonoscopy screening ranging from $654 in St. Louis to $1600 in Baltimore City.CONCLUSIONSVariations in how sites contracted with providers and in the services provided through CRCSDP affected the cost of clinical services and the complexity of collecting cost data. Health officials may find these data useful in program planning and budgeting. Cancer 2013;119(15 suppl):2863–9. © 2013 American Cancer Society.
Moving forward: Using the experience of the CDCs' Colorectal Cancer Screening Demonstration Program to guide future colorectal cancer programming efforts
Authors: Seeff Laura C. , DeGroff Amy , Joseph Djenaba A. , Royalty Janet , Tangka Florence K. L. , Nadel Marion R. , Plescia Marcus 
Published: July 2013

BACKGROUNDThe Centers for Disease Control and Prevention (CDC) established and supported a 4‐year Colorectal Cancer Screening Demonstration Program (CRCSDP) from 2005 to 2009 for low‐income, under‐ or uninsured men and women aged 50‐64 at 5 sites in the United States.METHODSA multiple methods evaluation was conducted including 1) a longitudinal, comparative case study of program implementation, 2) the collection and analysis of client‐level screening and diagnostic services outcome data, and 3) the collection and analysis of program‐ and patient‐level cost data.RESULTSSeveral themes emerged from the results reported in the series of articles in this Supplement. These included the benefit of building on an existing infrastructure, strengths and weakness of both the 2 most frequently used screening tests (colonoscopy and fecal occult blood tests), variability in costs of maintaining this screening program, and the importance of measuring the quality of screening tests. Population‐level evaluation questions could not be answered because of the small size of the participating population and the limited time frame of the evaluation. The comprehensive evaluation of the program determined overall feasibility of this effort.CONCLUSIONSCritical lessons learned through the implementation and evaluation of the CDC's CRCSDP led to the development of a larger population‐based program, the CDC's Colorectal Cancer Control Program (CRCCP). Cancer 2013;119(15 suppl):2940–6. © 2013 American Cancer Society.
Costs of planning and implementing the CDC's Colorectal Cancer Screening Demonstration Program
Authors: Subramanian Sujha , Tangka Florence K. L. , Hoover Sonja , Beebe Maggie C. , DeGroff Amy , Royalty Janet , Seeff Laura C. 
Published: July 2013

BACKGROUNDThe Centers for Disease Control and Prevention (CDC) initiated the Colorectal Cancer Screening Demonstration Program (CRCSDP) to explore the feasibility of establishing a large‐scale colorectal cancer screening program for underserved populations in the United States. The authors of the current report provide a detailed description of the total program costs (clinical and nonclinical) incurred during both the start‐up and service delivery (screening) phases of the 4‐year program.METHODSTailored cost questionnaires were completed by staff at the 5 CRCSDP sites. Cost data were collected for clinical services and nonclinical programmatic activities (program management, data collection, and tracking, etc). In‐kind contributions also were measured and were assigned monetary values.RESULTSNearly $11.3 million was expended by the 5 sites over 4 years, and 71% was provided by the CDC. The proportion of funding spent on clinical service delivery and service delivery/patient support comprised the largest proportion of cost during the implementation phase (years 2‐4). The per‐person nonclinical cost comprised a substantial portion of total costs for all sites. The cost per person screened varied across the 5 sites and by screening method. Overall, economies of scale were observed, with lower costs resulting from larger numbers of individuals screened.CONCLUSIONSPrograms incur substantial variable costs related to clinical services and semivariable costs related to nonclinical services. Therefore, programs that serve large populations are likely to achieve a lower cost per person.Cancer2013;119(15 suppl):2855–62.©2013 American Cancer Society.
Outpatient colonoscopy complications in the CDC's Colorectal Cancer Screening Demonstration Program
Authors: Castro Georgina , Azrak M. Fuad , Seeff Laura C. , Royalty Janet 
Published: July 2013

BACKGROUNDTo the authors's knowledge, there are few published prospective cohort studies of colonoscopy complications in patients at average risk for colorectal cancer who received colorectal cancer screening from a community‐based program. In this article, the authors report the rate of colonoscopy complications in the Centers for Disease Control and Prevention (CDC)'s Colorectal Cancer Screening Demonstration Program (CRCSDP), which provided colorectal cancer screening to a medically underserved population aged 50 years to 64 years for screening, diagnostic follow‐up after positive stool blood tests, and surveillance purposes.METHODSClinical data were collected prospectively from 5 community‐based colorectal cancer screening programs. Complications were identified by reviewing the standardized clinical data and medical complication reporting forms submitted by the programs to the CDC. Serious complications were defined as conditions or symptoms that resulted in hospital admission within 30 days after the procedure, including perforation, gastrointestinal bleeding requiring or not requiring blood transfusion, cardiopulmonary events, postpolypectomy syndrome, excessive abdominal pain, or death.RESULTSA total of 3215 individuals underwent 3355 colonoscopies. Of these, 89% of the colonoscopies were conducted for screening, 9% were conducted for diagnostic follow‐up, and 2% were conducted for surveillance purposes. The mean age of the individuals was 55.9 years. Eight individuals experienced serious complications, for an incidence of 2.38 per 1000 colonoscopies. Three patients experienced bowel perforations that required surgery, 1 patient was hospitalized for postpolypectomy bleeding, 3 patients experienced cardiopulmonary events, and 1 patient visited the emergency room for excessive abdominal pain and underwent surgery for an identified colorectal mass. No deaths were reported.CONCLUSIONSIn the CDC's CRCSDP, in which a total of 3215 individuals underwent 3355 colonoscopies, the overall incidence of serious complications from colonoscopy was found to be low. Cancer 2013;119(15 suppl):2849‐54. © 2013 American Cancer Society.