bluuebunny/crossref_metadata_2025_split huggingface dataset:
Le corps de narcisse. Petite note interrogative...
Authors: Joly Fabien 
Published: December 2014

Depuis l’observation naturaliste et banale d’une petite fille prenant un plaisir narcissique aux trois étages de son élation purement fonctionnelle de maîtrise psychomotrice, de son plaisir imaginaire interne à « être grande » et du plaisir à se faire admirer dans le miroir des yeux de sa mère et des autres est interrogée la question du corps et des liens corps/psyché dans le registre du narcissisme. À partir de la fixation sur le spéculaire dans les différentes évocations du mythe de Narcisse et dans la théorie notamment inspirée par Lacan et le stade dit de « l’enfant au miroir », sont rappelées l’ombre monumentale de H. Wallon et l’idée d’une pensée du développement qui ne fasse fi ni de la relation à l’autre ni des enjeux, des expériences et éprouvés corporels sous-jacents
Enlever une partie du cœur
Authors: Baudin Marianne 
Published: December 2014

Tout en faisant référence à des artistes (A. Daudet, C. Pozzi, F. Khalo, P. Klee, C. Angot, etc.) ayant pu exprimer par leurs œuvres les souffrances vécues dans leurs corps, l’article est centré sur le cas d’une patiente atteinte d’hypertension avec risque cardiaque majeur, victime dans l’enfance d’un viol incestueux. Le travail analytique, dont les principales étapes et enjeux sont décrits, a permis le réinvestissement d’activités et de réalisations sublimatoires longtemps gelées : écriture d’un journal, jeu théâtral et dessin.
The Use of Pharmacogenomics for Selection of Therapy in Non-Small-Cell Lung Cancer
Authors: Karim Nagla A. , Bui Hai , Pathrose Peterson , Starnes Sandra , Patil Ninad , Shehata Mahmoud , Mostafa Ahmed , Rao Mb , Zarzour Ahmad , Anderson Marshall 
Published: December 2014

Introduction Performance status (PS) is the only known clinical predictor of outcome in patients with advanced non-small-cell lung cancer (NSCLC), although pharmacogenomic markers may also correlate with outcome. The aim of our study was to correlate clinical and pharmacogenomic measures with overall survival. Methods This was an IRB approved, retrospective study in which the medical records of 50 patients with advanced NSCLC from 1998–2008 were reviewed, and gender, race, PS, and chemotherapy regimens were documented. Stromal expression of pharmacogenomic markers (VEGFR, ERCC1, 14-3-3σ, pAKT, and PTEN) was measured. Clinical factors and pharmacogenomics markers were compared to overall survival using a Cox proportional hazards model. Results Forty patients received platinum-based therapy. Median age was 65 years. Improved PS, female gender, and gemcitabine therapy were significantly associated with longer overall survival ( P = 0.004, P = 0.04, and P = 0.003, respectively). Age was not associated with survival. Caucasians had better overall survival in comparison to African Americans with median survival of 14.8 months versus 10.4 months ( P = 0.1). Patients treated with platinum-based therapy had better survival of 15 months versus 8 months for non-platinum based therapy ( P = 0.01). There was no significant association between any of the pharmacogenomics markers and overall survival other than in patients treated with platinum, in whom ERCC1 negativity was strongly associated with longer survival ( P = 0.007). Conclusion ERCC1 negativity with platinum therapy, gemcitabine therapy, good PS, and female gender all correlated with improved overall survival in patients with advanced NSCLC.
On the Rate of Convergence of Empirical Measures in ∞-transportation Distance
Authors: García Trillos Nicolás , Slepčev Dejan 
Published: December 2014

AbstractWe consider random i.i.d. samples of absolutely continuous measures on bounded connected domains. We prove an upper bound on the ∞-transportation distance between the measure and the empirical measure of the sample. The bound is optimal in terms of scaling with the number of sample points.
Validation of a priori CME arrival predictions made using real‐time heliospheric imager observations
Authors: Tucker‐Hood Kimberley , Scott Chris , Owens Mathew , Jackson David , Barnard Luke , Davies Jackie A. , Crothers Steve , Lintott Chris , Simpson Robert , Savani Neel P. , Wilkinson J. , Harder B. , Eriksson G. M. , L Baeten E. M. , Wan Wah Lily Lau 
Published: December 2014

AbstractBetween December 2010 and March 2013, volunteers for the Solar Stormwatch (SSW) Citizen Science project have identified and analyzed coronal mass ejections (CMEs) in the near real‐time Solar Terrestrial Relations Observatory Heliospheric Imager observations, in order to make “Fearless Forecasts” of CME arrival times and speeds at Earth. Of the 60 predictions of Earth‐directed CMEs, 20 resulted in an identifiable Interplanetary CME (ICME) at Earth within 1.5–6 days, with an average error in predicted transit time of 22 h, and average transit time of 82.3 h. The average error in predicting arrival speed is 151 km s−1, with an average arrival speed of 425km s−1. In the same time period, there were 44 CMEs for which there are no corresponding SSW predictions, and there were 600 days on which there was neither a CME predicted nor observed. A number of metrics show that the SSW predictions do have useful forecast skill; however, there is still much room for improvement. We investigate potential improvements by using SSW inputs in three models of ICME propagation: two of constant acceleration and one of aerodynamic drag. We find that taking account of interplanetary acceleration can improve the average errors of transit time to 19 h and arrival speed to 77 km s−1.
Information Theory
Authors: Mair Patrick , Eye Alexander 
Published: December 2014

Abstract

Communication and information theory were founded by Shannon (1948). Shannon and Weaver (1949) developed the classical system of communication and the mathematical bases of communication. Information theory is concerned with measuring the degree to which a message provides one with knowledge one did not possess before. The broadest understanding of information theory includes all problems for which it is sensible to use the word
information
in its usual sense. The amount of information that is transmitted is scaled in units of
entropy
. Information theory allows one to analyze and assess a situation in which a signal that was selected from an
a priori
specified set is transmitted through a channel with limited capacity. The output of the channel is not determined by the input. Modern applications of information theory can be found in electronics and in the social sciences.
Generalized Estimating Equations: Overview
Authors: Hardin James W. 
Published: December 2014

AbstractCorrelated datasets arise from repeated measures studies where multiple observations are collected from a specific sampling unit (a specific patient's status over time), or from grouped orclustered datawhere observations are grouped based on sharing some common characteristic (animals in a specific litter). When measurements are collected over time, the term longitudinal or panel data is preferred. Generalized estimating equations provide a framework for analyzing correlated data. This framework extends the generalized linear models methodology, which assumes independent data. We discuss the estimation of model parameters and associated variances via generalized estimating equation methodology.
Risk Perception
Authors: Everitt Brian S. 
Published: December 2014

Abstract
Life is a risky business, and deciding which risks are worth taking and which should be avoided has important implications both for an individual's lifestyle, and the way society operates. The benefits gained from taking a risk need to be weighed against the possible disadvantages. Acceptable risk is proportional to the amount of benefits. For the individual, living life to the fullest means achieving a balance between reasonable and unreasonable risk, and this will often be a matter of judgement depending largely on the individual's personality. However, in society as a whole, where the same balancing act is required, it has to be achieved through political action and legislation.
Compartmental Analysis
Authors: Becka Michael 
Published: December 2014

Abstract
Ecological, toxicological, and pharmacological research is often concerned with the answer to the question of how a substance is processed within a biological system. The exact knowledge of the corresponding kinetic pattern forms the basis for a useful answer. In order to understand and to characterize kinetic processes, as well as to identify nonlinear kinetics, compartmental analysis yields a useful approach.
Extremes: Spatial Parametric Modeling
Authors: Davison Anthony C. 
Published: December 2014

AbstractStatistics of spatial extremes is developing very rapidly, owing to the demands of applications in the environmental sciences and the insurance and risk industries. This article sketches the main ideas, based on classical extreme value statistics. The two main threads of work are the fitting of max‐stable models to spatial extremes, and the use of latent variable models, the latter typically in a Bayesian context.
Markov Random Field Models
Authors: Kaiser Mark S. 
Published: December 2014

AbstractStatistical models formulated on the basis of Markov random fields (MRFs) constitute an appealing approach to the analysis of data that exhibit complex dependence structures. Such data arise commonly in problems of a spatial or spatiotemporal nature, although MRFs are a general mathematical construct that may be used in other situations such as, for example, the representation of genetic dependence among organisms. Within the context of statistical modeling, a MRF may be defined for any set of random variables defined at a discrete point.
Point Processes, Dynamic
Authors: Ensor Katherine Bennett 
Published: December 2014

Abstract
This article deals with the specification and estimation of the intensity rate of point processes. The dynamics can include an arbitrary number of changes of level or modeling the intensity rate as a continuous function of exogenous variables. For discrete change points, the change points can be specified online as the process is observed or in advance with techniques that allow for the estimation of number and time location of changes. The classes of conditional duration models or autoregressive conditional duration models allow direct modeling of the intensity rate of a point process. In spatial dynamic point processes, changes may be governed by topology of the region.
Stochastic Models
Authors: Preisler Haiganoush K. 
Published: December 2014

AbstractEnvironmental scientists use models – a system of assumptions presented in a mathematical framework – to study complex interrelationships in ecological processes and to assess and predict the impact of our actions on the environment, among other things. There are a variety of model types: stochastic, deterministic, numerical, to name a few. A major concept that distinguishes stochastic models from other models is the idea of probability, or randomness, that is explicit in all stochastic models.
Synthesis of Secondary Amides from N‐Substituted Amidines by Tandem Oxidative Rearrangement and Isocyanate Elimination
Authors: Debnath Pradip , Baeten Mattijs , Lefèvre Nicolas , Daele Stijn Van , Maes Bert U. W. 
Published: December 2014

AbstractIn this work an efficient tandem process transforming N‐substituted amidines into secondary amides has been described. The process involves N‐acylurea formation by reaction of the substrate with bis(acyloxy)(phenyl)‐λ3‐iodane followed by isocyanate elimination. The periodinane reagents are obtained from the commercially available phenyliodine(III) diacetate [PhI(OAc)2, (PIDA)] by ligand exchange with carboxylic acids. The N‐substituted amidine substrates are easily synthesized from readily available nitriles. The method is applicable for secondary amide synthesis, based on both aliphatic and (hetero)aromatic amines, including challenging amides consisting of sterically hindered acids and amines. Moreover, the protocol allows one to combine steric bulk with electron deficiency in the target amides (aniline based). Such compounds are difficult to synthesize efficiently based on classical condensation reactions involving carboxylic acids and amines. Overall, the synthetic protocol transforms a nitrile into a secondary amide in both aliphatic and (hetero)aromatic systems.magnified image
Supramolecular Catalysis in the Synthesis of Substituted 1 H‐Tetrazoles from Isonitriles by a Self‐Assembled Hexameric Capsule
Authors: Giust Sonia , La Sorella Giorgio , Sperni Laura , Fabris Fabrizio , Strukul Giorgio , Scarso Alessandro 
Published: December 2014

AbstractThe synthesis of substituted 1H‐tetrazoles from aliphatic or aromatic isonitriles and trimethylsilyl azide can be efficiently promoted by the hexameric capsule of resorcin[4]arene as a supramolecular self‐assembled catalyst. The reaction is sensitive to the size and nature of the substrate and is driven by encapsulation of the reagents within the cavity of the supramolecular catalyst.
Oscillations in the Stability of Consecutive Chemical Bonds Revealed by Ion‐Induced Desorption
Authors: Ossowski Jakub , Rysz Jakub , Krawiec Mariusz , Maciazek Dawid , Postawa Zbigniew , Terfort Andreas , Cyganik Piotr 
Published: December 2014

AbstractWhile it is a common concept in chemistry that strengthening of one bond results in weakening of the adjacent ones, no results have been published on if and how this effect protrudes further into the molecular backbone. By binding molecules to a surface in the form of a self‐assembled monolayer, the strength of a primary bond can be selectively altered. Herein, we report that by using secondary‐ion mass spectrometry, we are able to detect for the first time positional oscillations in the stability of consecutive bonds along the adsorbed molecule, with the amplitudes diminishing with increasing distance from the molecule–metal interface. To explain these observations, we have performed molecular dynamics simulations and DFT calculations. These show that the oscillation effects in chemical‐bond stability have a very general nature and break the translational symmetry in molecules.
Scanning‐Tunneling‐Spectroscopy‐Directed Design of Tailored Deep‐Blue Emitters
Authors: Sanning Jan , Ewen Pascal R. , Stegemann Linda , Schmidt Judith , Daniliuc Constantin G. , Koch Tobias , Doltsinis Nikos L. , Wegner Daniel , Strassert Cristian A. 
Published: December 2014

AbstractFrontier molecular orbitals can be visualized and selectively set to achieve blue phosphorescent metal complexes. For this purpose, the HOMOs and LUMOs of tridentate PtII complexes were measured using scanning tunneling microscopy and spectroscopy. The introduction of electron‐accepting or ‐donating moieties enables independent tuning of the frontier orbital energies, and the measured HOMO–LUMO gaps are reproduced by DFT calculations. The energy gaps correlate with the measured and the calculated energies of the emissive triplet states and the experimental luminescence wavelengths. This synergetic interplay between synthesis, microscopy, and spectroscopy enabled the design and realization of a deep‐blue triplet emitter. Finding and tuning the electronic “set screws” at molecular level constitutes a useful experimental method towards an in‐depth understanding and rational design of optoelectronic materials with tailored excited state energies and defined frontier‐orbital properties.
Multidimensional De Novo Design Reveals 5‐HT2B Receptor‐Selective Ligands
Authors: Rodrigues Tiago , Hauser Nadine , Reker Daniel , Reutlinger Michael , Wunderlin Tiffany , Hamon Jacques , Koch Guido , Schneider Gisbert 
Published: December 2014

AbstractWe report a multi‐objective de novo design study driven by synthetic tractability and aimed at the prioritization of computer‐generated 5‐HT2B receptor ligands with accurately predicted target‐binding affinities. Relying on quantitative bioactivity models we designed and synthesized structurally novel, selective, nanomolar, and ligand‐efficient 5‐HT2B modulators with sustained cell‐based effects. Our results suggest that seamless amalgamation of computational activity prediction and molecular design with microfluidics‐assisted synthesis enables the swift generation of small molecules with the desired polypharmacology.
Supply Chain Management as Private Sector Regulation: What does it Mean for Business Strategy and Public Policy?
Authors: Fiorino Daniel J. , Bhan Manjyot 
Published: December 2014

AbstractThe growing practice of environmental supply chain management by firms constitutes private sector regulation that is analogous in many ways to public sector regulation. Similarly to their public counterparts, private sector regulators set standards, apply standards, monitor for compliance, apply sanctions and require corrective action. Private sector regulation differs, however, in the source of authority, external oversight, analytical requirements, public participation and available sanctions. This article argues that supply chain management by firms goes beyond business objectives by creating positive environmental externalities for society, and that more systematic study of the similarities and contrasts between the two forms of regulation may provide valuable lessons for both. Further, it may be possible to increase the effectiveness of private sector regulation to achieve both public societal and private business goals. From a business perspective, supply chain management enables firms to strategically redefine their relationships with government, reduce uncertainty and promote goal‐oriented collaboration. Copyright © 2014 John Wiley & Sons, Ltd and ERP Environment
Hydroxy‐Functionalized Imidazolium Bromides as Catalysts for the Cycloaddition of CO2 and Epoxides to Cyclic Carbonates
Authors: Anthofer Michael H. , Wilhelm Michael E. , Cokoja Mirza , Drees Markus , Herrmann Wolfgang A. , Kühn Fritz E. 
Published: December 2014

AbstractHydroxy‐functionalized mono‐ and bisimidazolium bromides were synthesized and applied as catalysts for the cycloaddition of CO2 and epoxides to cyclic carbonates. A catalyst screening showed the influence of the number of protic hydrogen atoms at the cation for the activation of epoxides. The most active catalyst operates at very mild reaction conditions (70 °C, 0.4 MPa CO2) and can be easily recycled ten times without loss of activity.
Convenient Synthesis of Quinolines from α‐2‐Nitroaryl Alcohols and Alcohols via a Ruthenium‐catalyzed Hydrogen Transfer Strategy
Authors: Xie Feng , Zhang Min , Chen Mengmeng , Lv Wan , Jiang Huanfeng 
Published: December 2014

AbstractA new and straightforward method for convenient synthesis of quinolines via a ruthenium‐catalyzed hydrogen‐transfer strategy has been demonstrated. By employing a commercially available ruthenium catalyst system, different α‐2‐nitroaryl alcohols were efficiently converted in combination with a variety of alcohols into various substituted products in reasonable to good yields upon isolation. The synthetic protocol is operationally simple with a broad substrate scope, and there is no need for the use of specialized reducing agents, making it a practical approach for versatile preparation of various quinoline derivatives.
Li[B(OCH2CF3)4]: Synthesis, Characterization and Electrochemical Application as a Conducting Salt for LiSB Batteries
Authors: Rohde Michael , Eiden Philipp , Leppert Verena , Schmidt Michael , Garsuch Arnd , Semrau Guenter , Krossing Ingo 
Published: December 2014

AbstractA new Li salt with views to success in electrolytes is synthesized in excellent yields from lithium borohydride with excess 2,2,2‐trifluorethanol (HOTfe) in toluene and at least two equivalents of 1,2‐dimethoxyethane (DME). The salt Li[B(OTfe)4] is obtained in multigram scale without impurities, as long as DME is present during the reaction. It is characterized by heteronuclear magnetic resonance and vibrational spectroscopy (IR and Raman), has high thermal stability (Tdecomposition>271 °C, DSC) and shows long‐term stability in water. The concentration‐dependent electrical conductivity of Li[B(OTfe)4] is measured in water, acetone, EC/DMC, EC/DMC/DME, ethyl acetate and THF at RT In DME (0.8 mol L−1) it is 3.9 mS cm−1, which is satisfactory for the use in lithium‐sulfur batteries (LiSB). Cyclic voltammetry confirms the electrochemical stability of Li[B(OTfe)4] in a potential range of 0 to 4.8 V vs. Li/Li+. The performance of Li[B(OTfe)4] as conducting salt in a 0.2 mol L−1 solution in 1:1 wt % DME/DOL is investigated in LiSB test cells. After the 40th cycle, 86 % of the capacity remains, with a coulombic efficiency of around 97 % for each cycle. This indicates a considerable performance improvement for LiSB, if compared to the standard Li[NTf2]/DOL/DME electrolyte system.
Fabrication and Characterisation of Membrane‐Based Gold Electrodes
Authors: Bakmand Tanya , Kwasny Dorota , Dimaki Maria , Svendsen Winnie E. 
Published: December 2014

AbstractThis work presents a versatile, membrane based electrochemical sensor with thin film electrodes fabricated through E‐beam evaporation directly on porous materials (membranes). Here, the fabrication of the electrodes is described along with possible methods for integration in fluidic systems and characterisation of the electrodes through cyclic voltammetry (CV). The continued porous nature of the membranes after metal deposition is documented and its robustness and stability is investigated. Furthermore, amperometric sensing of dopamine is demonstrated as a proof of concept to validate the usability of the membrane sensor.
Community‐Based Theater and Adults with Psychiatric Disabilities: Social Activism, Performance and Community Engagement
Authors: Faigin David A. , Stein Catherine H. 
Published: December 2014

AbstractThe present study is an in‐depth qualitative inquiry with an established theater troupe composed of adults living with psychiatric disabilities known as The Stars of Light. A grounded theory methodology is used to describe dimensions of social activism and characteristics of theater as a medium of engagement at the individual, setting/troupe, and community levels of analysis. Analysis of a broad scope of interview data, performance content, community contacts, and historical data from the troupe’s 19‐year history led to the identification of eight emergent theoretical concepts formulated from 17 supporting associated themes. The theoretical concepts characterize the impacts of community‐based theater in the lives of participants, and theater troupe processes that contribute to community education and positive social change for adults living with psychiatric disabilities. Advantages, limitations, and future directions for research and action in community‐based theater settings are discussed within the context of present research findings.
Right‐sided infective endocarditis as a potentially fatal complication in patients with long‐term refractory severe bradyarrhythmia after cervical spinal cord injury: A case report
Authors: Miura Naoki , Suzuki Hideaki , Maesawa Shota , Koakutsu Tomoaki , Matsumoto Yasuharu , Fukuda Koji , Kagaya Yutaka , Kushimoto Shigeki , Shimokawa Hiroaki 
Published: December 2014

AbstractBradyarrhythmia is usually a spontaneously subsiding complication of cervical spinal cord injury. However, in severe cases, it can lead to cardiac arrest. We report a case of cervical spinal cord injury, complicated by right‐sided infective endocarditis after the placement of a temporary pacing catheter in the right ventricle for severe bradyarrhythmia that led to cardiac arrest. Although the patient's condition was successfully treated by pacing catheter removal and pharmacological therapy, right‐sided infective endocarditis would be a fatal complication in cases of cervical spinal cord injury where cardiac pacing is required for long‐term refractory severe bradyarrhythmia.