bluuebunny/crossref_metadata_2025_split huggingface dataset:
Subcutaneous adipose tissue measurements and better metabolic prediction
Authors: Ristic Petar , Bokonjic Dubravko , Zivkovic Vladimir , Jakovljevic Vladimir , Zdravkovic Marija , Pejovic Janko , Ristic Dragana , Mladenovic Jovan 
Published: December 2012

Abstract
The aim of the study was to establish the importance of an additional measurement of subcutaneous adipose tissue thickness (SAT) on a predetermined position on the waistline, and its relation to waist measurements as an improvement of metabolic prediction in equally obese subjects. One hundred and forty two consecutive patients were enrolled in the study: stratified by weight as normal (body mass index — BMI 20–25 kg/m2), overweight (BMI 25–30 kg/m2) and obese (BMI >30 kg/m2); and by fasting glucose level as normoglycemic, impaired fasting glucose (IFG), or with type 2 diabetes mellitus (T2DM). SAT was measured in relaxed expiration, 3 cm left of the umbilicus, with ultrasound. Fasting blood samples for glucose, insulin and HbAlc were taken. Waist circumference was slightly higher in the IFG (112.8 cm) and normoglycemic groups (115.62 cm), compared to T2DM (108.15 cm). The T2DM group had a lower average SAT (2.7 cm) than both the IFG group (3.4 cm, p<0.01) and the normoglycemic group (4.2cm, p=0.001). The homeostatic model of assessment for insulin resistance (HOMA IR) was the lowest in normoglycemic and the highest in IFG group. Waistline radius to SAT ratio provides better insight into the deterioration of glucose metabolism than standard anthropometric markers of abdominal obesity in equally obese patients.
Prevalence of Legionella antibodies in immunocompromised patients
Authors: Sikora Agnieszka , Kozioł-Montewka Maria , Książek Andrzej , Grzebalska Agnieszka , Bednarek-Skublewska Anna , Steć Anna , Rudzki Sławomir , Furmaga Jacek , Paluch-Oleś Jolanta , Magryś Agnieszka , Karaś Magdalena 
Published: December 2012

Abstract
L'innovation dans les services comme un pilier de l'économie fondée sur la connaissance
Authors: Cherchem Mohamed 
Published: December 2012

D’après la littérature qui existe sur l’économie de la connaissance, le contenu du concept E.F.C est abordé à travers différents thèmes en distinguant : connaissance et information, la coopération et la coordination des acteurs publics et privés, économie de la connaissance et ressources humaines, la place des TIC dans l’économie de la connaissance et l’innovation dans les services. L’innovation et l’économie fondées sur la connaissance sont au centre de beaucoup de débats sur la compétitivité des entreprises, notamment des services. Ce papier porte sur l’innovation dans les services financiers et L’EFC. L’objectif de ce travail est d’articuler ces deux problématiques en s’intéressant à la question de l’innovation dans les services et L’EFC. Une étude empirique nous permet d’évaluer et d’estimer la perception des responsables des banques et des assurances publiques algériennes envers le concept de L’EFC et l’innovation ainsi que l’attitude des responsables envers les nouveaux produits et services et L’EFC. Cet article travaille à apporter un éclairage sur cette problématique.
Complémentarité ou adversité des stratégies d'innovation et d'imitation dans le secteur agroalimentaire français ?
Authors: Benyahia-Taibi Ghalia 
Published: December 2012

Cet article tente de dévoiler l’existence des pratiques d’imitation dans le secteur agroalimentaire français et l’importance de ces stratégies dans le développement du secteur. L’investigation sur le terrain est de type qualitatif avec une étude documentaire basée sur la revue LSA (Libre-Service Actualités). Les résultats obtenus indiquent que l’imitation est une bonne stratégie permettant de répondre aux exigences des marchés agroalimentaires. Mots- clés : stratégie d’imitation, innovation, secteur agroalimentaire français.
Métamorphoses de l’idée d’empire à la Renaissance
Authors: Ménissier Thierry 
Published: December 2012

Époque de transition, la Renaissance
connaît une série d’évolutions de l’idée politique d’empire (héritée
du Moyen Âge) vers la réalité moderne d’un vaste marché coordonnant
progressivement les économies nationales particulières et leurs
réseaux d’influence. Ces évolutions permettent-elles d’évoquer la mise
en place d’une « version économique de l’empire » ? Peut-on regarder
ce qui se joue à la Renaissance, saisie à travers ses relations
géopolitiques, comme la préfiguration de la globalisation ? L’article
examine ces questions à partir de plusieurs hypothèses et défend la
thèse que l’idée d’empire subit à cette époque des « métamorphoses »,
c’est-à-dire des évolutions qui en modifient le concept, notamment en
ce qui concerne le rapport entre domination et territorialité.
Gattinara et la « monarchie impériale » de Charles Quint. Entre millénarisme, translatio imperii et droits du Saint-Empire
Authors: d’Amico Juan Carlos 
Published: December 2012

Spreading the universal monarchy
myth in the early 16th century was closely linked to the
magnitude of the territories controlled by Charles V. For the imperial
chancellor Mercurino Gattinara, universal and messianic ideas, which
were integrated into the symbolism of the Empire, were to legitimate a
policy that aimed at giving a more rational structure to Charles’
territories and at securing a prominent influence for the Habsburg
family in the whole of Europe. Gattinara imagined a kind of
supranational monarchy, organised in accordance with the mythical
model of the Roman Empire, which would be able to guarantee peace
under the aegis of Christianity.
L’inventio de la Nouvelle Espagne. Rhétorique et domination territoriale du Nouveau Monde
Authors: Ceceña Alvarez René 
Published: December 2012

Ce texte propose une analyse des mécanismes
argumentatifs mis en œuvre dans les lettres que Hernán Cortés,
conquistador du Mexique, a adressées à Charles V (Cartas de Relación) pour légitimer sa conquête du
territoire qui deviendra la Nouvelle Espagne et, par ce biais, le
Nouveau Monde. Il s’agit en particulier de montrer l’emploi du concept
rhétorique d’inventio dans le passage d’une
appropriation conceptuelle du « Nouveau Monde » (par l’élaboration de
ce concept) à sa domination territoriale (la fondation de Veracruz et
la création de la Nouvelle Espagne).
Le jeu des échelles. Le pouvoir et son inscription spatiale dans les cartographies et les descriptions du Saint-Empire et de ses territoires au XVIe siècle
Authors: Chassagnette Axelle 
Published: December 2012

Au XVIe siècle, le Saint Empire romain de
nation allemande constitue un ensemble politique complexe, caractérisé
par un système à plusieurs niveaux de représentation politique et par
l’existence de multiples États placés sous l’autorité impériale.
L’étude des cartes et des descriptions géographiques de l’espace
germanique produites à cette période met au jour la compréhension
qu’avaient les contemporains des formes de souveraineté existant dans
l’Empire et ses territoires. Elle montre notamment que le pouvoir
impérial, à la différence des pouvoirs territoriaux, n’était pas conçu
au premier chef comme une forme d’autorité s’exerçant sur un espace,
mais comme une entité juridique et institutionnelle chargée d’assurer
le fonctionnement politique et l’unité de l’Empire.
Les États pontificaux face à Philippe II, marge ou centre alternatif de la Monarchie catholique ? Retour sur les fondements juridiques, politiques et pragmatiques d’un empire conjoncturel
Authors: Jeanne Boris 
Published: December 2012

The Catholic Monarchy is the
short-lived dynastic union (1580-1640) between the kingdoms of Spain
and Portugal. By returning on the legal, political and pragmatic
foundations of this empire which cannot be called Empire (because this
name belongs to the Holy Roman Empire of the cousins of Vienna), the
article tries to seize better the internal functioning of this
heterogeneous political set, by adopting two points of view: that of
America (how the notion of Catholic Monarchy is understood in the
reynos, far from Madrid and Lisbon) and that of Rome (how Holy See
reaches - or not - to exist in the heart of this space). It emerges
from it that the pope and the Catholic King are natural allies (around
the Roman Christianity) but not objectives (their purposes do not
match), and that Rome and Mexico as well picture themselves not as
margins of the Catholic Monarchy, but as real centers.
Concurrent Criterion Validity of the Safe Driving Behavior Measure: A Predictor of On-Road Driving Outcomes
Authors: Classen Sherrilene , Wang Yanning , Winter Sandra M. , Velozo Craig A. , Lanford Desiree N. , Bédard Michel 
Published: December 2012

Abstract
We determined the concurrent criterion validity of the Safe Driving Behavior Measure (SDBM) for on-road outcomes (passing or failing the on-road test as determined by a certified driving rehabilitation specialist) among older drivers and their family members–caregivers. On the basis of ratings from 168 older drivers and 168 family members–caregivers, we calculated receiver operating characteristic curves. The drivers’ area under the curve (AUC) was .620 (95% confidence interval [CI] = .514–.725, p = .043). The family members–caregivers’ AUC was .726 (95% CI = .622–.829, p ≤ .01). Older drivers’ ratings showed statistically significant yet poor concurrent criterion validity, but family members–caregivers’ ratings showed good concurrent criterion validity for the criterion on-road driving test. Continuing research with a more representative sample is being pursued to confirm the SDBM’s concurrent criterion validity. This screening tool may be useful for generalist practitioners to use in making decisions regarding driving.
Importance of Tissue Morphology Relative to Patient Reports of Symptoms and Functional Limitations Resulting From Median Nerve Pathology
Authors: Roll Shawn C. , Evans Kevin D. , Li Xiaobai , Sommerich Carolyn M. , Case-Smith Jane 
Published: December 2012

Abstract
Significant data exist for the personal, environmental, and occupational risk factors for carpal tunnel syndrome. Few data, however, explain the interrelationship of tissue morphology to these factors among patients with clinical presentation of median nerve pathology. Therefore, our primary objective was to examine the relationship of various risk factors that may be predictive of subjective reports of symptoms or functional deficits accounting for median nerve morphology. Using diagnostic ultrasonography, we observed real-time median nerve morphology among 88 participants with varying reports of symptoms or functional limitations resulting from median nerve pathology. Body mass index, educational level, and nerve morphology were the primary predictive factors. Monitoring median nerve morphology with ultrasonography may provide valuable information for clinicians treating patients with symptoms of median nerve pathology. Sonographic measurements may be a useful clinical tool for improving treatment planning and provision, documenting patient status, or measuring clinical outcomes of prevention and rehabilitation interventions.
Telling the Girls from the Boys and Children: Interpreting Παȋδεϛ in the Sexual Violence of Populace-Ravaging Ancient Warfare
Authors: Gaca Kathy L. 
Published: December 2012

AbstractIn andrapodizing or populace-ravaging ancient warfare, important Greek evidence discloses norms of martial rape meted out to girls and women in the attacked communities. This practice is unambiguously communicated when the sexually assaulted girls are designated in a female-specific way (e.g., as daughters) and they are said to be not yet ready for marriage. My main concern here is to clarify a presently ambiguous area in this regard. I show the critical import of recognizing when παȋδεϛ καί γυναȋκεϛ means that "girls and women" are subjected to this martial sexual aggression, not, as hitherto understood, "(boy and girl) children and women" or "women" alone with the παȋδεϛ set aside unscathed.
Lucretius 3.978-1023 and the Hellenistic Philosophical Polemics against the Grammarians
Authors: Marković Daniel 
Published: December 2012

Abstract
The paper examines closely the technique of recontextualization in Lucretius 3.978-1023 and sheds further light on the problems of its source and complex rhetorical goals. In order to prove erroneous the belief in the Underworld punishments described in Homer, which according to Epicurean teaching exist in real life, Lucretius uses a technique of careful selection and repetition of keywords in two different, juxtaposed contexts. The same technique is found in Seneca’s Letter 88, where Seneca seeks to show that typical school questions are worthless in comparison with their philosophical counterparts, oriented toward the realm of real life. The similarity is not only formal: both Seneca and Lucretius believe that the study of traditional poetry cannot offer adequate guidance for living. Seneca borrows his technique from the Hellenistic philosophical polemics against the grammarians, and Lucretius’s passage was most likely modeled after a similar one in Epicurus.
Synthesis of Oligodeoxynucleotides with 5′‐Caps Binding RNA Targets
Authors: Egetenmeyer Simone , Richert Clemens 
Published: December 2012

AbstractProtocols for the synthesis of oligodeoxynucleotides with a short peptidyl substituent linked to the 5′‐O‐terminus through a phosphodiester bond are presented. The example given is a peptidyl cap consisting of the residues of L‐prolinol, glycine, and the acyl residue of oxolinic acid. DNA probes with this cap, also known as ogOA cap, give melting point increases for duplexes with RNA targets and improve mismatch discrimination at the terminus. The cap is either introduced in one step, using a newly developed phosphoramidite reagent, or assembled on the DNA chain. The step‐wise assembly of the peptidyl chain is advantageous for combinatorial studies aimed at the optimization of a cap structure. The block coupling method, introducing the preassembled cap in one step, is attractive for routine use of a cap already optimized for a given application. Cap‐bearing probes can increase fidelity of hybridization in a genomic context. They can be synthesized by automated DNA synthesis. Curr. Protoc. Nucleic Acid Chem. 51:4.53.1‐4.53.21. © 2012 by John Wiley & Sons, Inc.
Binding to the DNA Minor Groove by Heterocyclic Dications: From AT‐Specific Monomers to GC Recognition with Dimers
Authors: Nanjunda Rupesh , Wilson W. David 
Published: December 2012

AbstractCompounds that bind in the DNA minor groove have provided critical information on DNA molecular recognition, have found extensive uses in biotechnology, and are providing clinically useful drugs against diseases as diverse as cancer and sleeping sickness. This review focuses on the development of clinically useful heterocyclic diamidine minor groove binders. These compounds have shown us that the classical model for minor groove binding in AT DNA sequences must be expanded in several ways: compounds with nonstandard shapes can bind strongly to the groove, water can be directly incorporated into the minor groove complex in an interfacial interaction, and the compounds can form cooperative stacked dimers to recognize GC and mixed AT/GC base pair sequences. Curr. Protoc. Nucleic Acid Chem. 51:8.8.1‐8.8.20. © 2012 by John Wiley & Sons, Inc.
The UCSC Genome Browser
Authors: Karolchik Donna , Hinrichs Angie S. , Kent W. James 
Published: December 2012

AbstractThe University of California Santa Cruz (UCSC) Genome Browser is a popular Web‐based tool for quickly displaying a requested portion of a genome at any scale, accompanied by a series of aligned annotation “tracks.” The annotations generated by the UCSC Genome Bioinformatics Group and external collaborators include gene predictions, mRNA and expressed sequence tag alignments, simple nucleotide polymorphisms, expression and regulatory data, phenotype and variation data, and pairwise and multiple‐species comparative genomics data. All information relevant to a region is presented in one window, facilitating biological analysis and interpretation. The database tables underlying the Genome Browser tracks can be viewed, downloaded, and manipulated using another Web‐based application, the UCSC Table Browser. Users can upload personal datasets in a wide variety of formats as custom annotation tracks in both browsers for research or educational purposes. This unit describes how to use the Genome Browser and Table Browser for genome analysis, download the underlying database tables, and create and display custom annotation tracks. Curr. Protoc. Bioinform. 40:1.4.1‐1.4.33. © 2012 by John Wiley & Sons, Inc.
Using the Wash U Epigenome Browser to Examine Genome‐Wide Sequencing Data
Authors: Zhou Xin , Wang Ting 
Published: December 2012

AbstractThis unit describes the Wash U Epigenome Browser, a next‐generation genomic data visualization system. The Browser currently hosts ENCODE and Roadmap Epigenomics data for human and model organisms. The Browser displays many sequencing‐based data sets across all or part of the genome, on specific gene sets or pathways, and in the context of their metadata. Investigators can order, filter, aggregate, classify, and display data interactively based on given feature sets including metadata features, annotated biological pathways, and user‐defined collections of genes or genomic coordinates. Further, statistical tests can be performed on selected data. Individual labs can upload their sequencing or array‐based data as custom tracks and display them in the context of consortium data, allowing for direct comparisons. The Browser is an increasingly important and widely accessible tool for deriving biological insights from unprecedented amounts of high‐quality genomic, epigenomic, and expression data. Curr. Protoc. Bioinform. 40:10.10.1‐10.10.14. © 2012 by John Wiley & Sons, Inc.
PatternLab: From Mass Spectra to Label‐Free Differential Shotgun Proteomics
Authors: Carvalho Paulo C. , Fischer Juliana S. G. , Xu Tao , Yates John R. , Barbosa Valmir C. 
Published: December 2012

AbstractPatternLab for proteomics is a self‐contained computational environment for analyzing shotgun proteomic data. Recent improvements incorporate modules to facilitate the computational analysis, such as FastaDBXtractor for sequence database preparation and ProLuCID runner for simplifying and managing the protein identification search engine; modules for pushing the limits on proteomics standards, such as SEPro, which relies on a semi‐labeled decoy approach for increasing confidence in filtering and organizing peptide spectrum matches; and modules with novel features, such as SEProQ for enabling label‐free quantitation by extracted ion chromatograms according to a distributed normalized ion abundance factor approach (dNIAF). Existing modules were also improved, such as the TFold module for pinpointing differentially expressed proteins. These new modules are integrated into the previously described arsenal of tools for further data analysis. Here we provide detailed instructions for operating and understanding them. Curr. Protoc. Bioinform. 40:13.19.1‐13.19.18. © 2012 by John Wiley & Sons, Inc.
Polyester Separators for Lithium‐Ion Cells: Improving Thermal Stability and Abuse Tolerance
Authors: Orendorff Christopher J. , Lambert Timothy N. , Chavez Carlos A. , Bencomo Marlene , Fenton Kyle R. 
Published: December 2012

AbstractThis report describes the preparation and performance of electro‐spun polyester‐based separators for lithium‐ion batteries. Polyester fibers (200–500 nm) are electro‐spun into nonwoven mats and pressed into separator sheets ∼55 μm thick. The resulting polyester separators are 75% porous, highly permeable (Gurley number (s/100 mL) = 6), and have good wettability with conventional carbonate‐based electrolyte. In NMC/graphite lithium‐ion cells, results show comparable performance to commercially available polyolefin separators (rate, capacity fade, and reactivity) but with improved thermal stability to >200 °C. The use of this higher melting temperature polymer separator is one approach to close the gap between potential thermal instabilities (softening, shrinking, melting, etc.) of separators and the onset of thermal runaway reactions of commonly used cathode materials.
Cutaneous B‐cell lymphomas: 2013 update on diagnosis, risk‐stratification, and management
Authors: Wilcox Ryan A. 
Published: December 2012

AbstractDisease overview: Approximately one‐fourth of cutaneous lymphomas are B‐cell derived and are generally classified into three distinct subgroups: primary cutaneous follicle‐center lymphoma (PCFCL), primary cutaneous marginal zone lymphoma (PCMZL), and primary cutaneous diffuse large B‐cell lymphoma, leg type (PCLBCL, LT). Diagnosis: Diagnosis and disease classification is based on histologic review and immunohistochemical staining of an appropriate skin biopsy. Pathologic review and an appropriate staging evaluation are necessary to distinguish primary cutaneous B‐cell lymphomas from systemic B‐cell lymphomas with secondary skin involvement. Risk‐stratification: Disease histology remains the most important prognostic determinant. Both PCFCL and PCMZL are indolent lymphomas that infrequently disseminate to extracutaneous sites and are associated with an excellent long‐term prognosis. In contrast, PCLBCL, LT is an aggressive lymphoma with an inferior prognosis. Risk‐adapted therapy: PCFCL and PCMZL patients with solitary or relatively few skin lesions may be affectively managed with local radiation therapy. Although single‐agent rituximab may be employed for patients with more widespread skin involvement, multiagent chemotherapy is rarely appropriate. In contrast, management of patients with PCLBCL, LT is comparable to the management of patients with systemic DLBCL. © Am. J. Hematol. 2013. © 2012 Wiley Periodicals, Inc.
Stroboskopgemische: pyrotechnische Mischungen mit oszillierendem Verbrennungsverhalten
Authors: Corbel Justine M. L. , van Lingen Joost N. J. , Zevenbergen John F. Z. , Gijzeman Onno L. J. , Meijerink Andries 
Published: December 2012

AbstractStroboskopgemische sind pyrotechnische Zusammensetzungen, die ein oszillierendes Verbrennungsverhalten zeigen; eine Dunkel‐ und eine Leuchtphase alternieren periodisch. Der Stroboskopeffekt wird in verschiedenen Bereichen, aber hauptsächlich in der Feuerwerksindustrie und im militärischen Bereich angewendet. Alle Stroboskopgemische, die in der Literatur beschrieben werden, wurden durch systematisches Ausprobieren entdeckt und die zugrundeliegenden Mechanismen bleiben ungeklärt. Viele oszillierende Systeme wurden beobachtet, und es wurden Theorien entwickelt, die auf chemischen Prozessen oder physikalischen Prozessen beruhen, um ihr instabiles Verhalten aufzuklären. Diese Systeme werden mit experimentellen Beobachtungen an Stroboskopgemischen verglichen.