bluuebunny/crossref_metadata_2025_split huggingface dataset:
Centralized resources for nurse practitioners: Common early experiences among leaders of six large health systems
Authors: Bahouth Mona N. , Ackerman Michael , Ellis Elizabeth F. , Fuchs Janet , McComiskey Carmel , Stewart Elizabeth S. , Thomson‐Smith Clare 
Published: November 2012

AbstractPurposeThis article describes common experiences of institutions that have pioneered the work of integrating nurse practitioners (NPs) into complex hospital environments and addresses effective strategies in achieving a centralized leadership model.Data sourcesWe conducted an informal, written survey and focus group discussions comparing experiences of leaders who were first in the position of centralizing resources and providing leadership for NPs in a hospital‐based setting. Experiences were compared and common practices summarized.ConclusionsThe numbers of NPs required to provide patient care in an ever‐growing, complex hospital environment are increasing rapidly. To meet the professional needs of these hospital‐based NPs, a strong centralized leadership approach should be utilized. An organized and centralized approach to credentialing, program development, orientation, and evaluation processes will become necessary as hospitals continue to hire increased numbers of NPs.Implications for practiceThis article summarizes important considerations for formulating centralized leadership models for hospital‐based NPs and provides a guide for administrators and NPs who are attempting to build similar models.
Removable orthodontic appliance with nickel–titanium spring to reposition the upper incisors in an autistic patient
Authors: Saito Kan , Jang Insan , Kubota Kazumi , Hoshino Tomonori , Hotokezaka Hitoshi , Yoshida Noriaki , Fujiwara Taku 
Published: November 2012

ABSTRACTA newly designed removable appliance with a shape‐memory wire was used for the orthodontic treatment of the anterior teeth in an 11‐year‐old child who had autism and intellectual disability. The device was designed to reduce the lateral incisor crossbite and the central incisors’ labial rotation. The child was treated for 1 year with this removable appliance. Tooth movement was analyzed using cephalograms and surface data were derived from study models.This device proved to be very durable. The lateral incisor crossbite was corrected, and the inclination of the upper central incisors and the interincisal angle were improved. This appliance exerts light and continuous orthodontic force, without requiring any adjustments of the spring wire. The appliance also facilitated orthodontic treatment in a child with intellectual disability in whom treatment with a standard orthodontic device would be unsuitable.
Attention deficit hyperactivity disorder, tic disorder, and allergy: is there a link? A nationwide population‐based study
Authors: Chen Mu‐Hong , Su Tung‐Ping , Chen Ying‐Sheue , Hsu Ju‐Wei , Huang Kai‐Lin , Chang Wen‐Han , Bai Ya‐Mei 
Published: November 2012

Background:  Attention deficit hyperactivity disorder (ADHD) and tic disorder usually co‐occur in the same individuals, but the underlying mechanisms remain unclear. Previous evidence has shown that a frequent coexistence of allergic diseases was noted in patients with ADHD or tic disorder. We attempted to investigate the possible link among ADHD, tic disorder, and various allergic diseases.Methods:  Utilizing the Taiwan National Health Insurance Research Database from 1996 to 2010, 5,811 patients with ADHD alone, 1,816 patients with tic disorder alone, and 349 patients with dual diagnoses of ADHD and tic disorder were identified and compared with age‐/gender‐matched controls (1:4) in an investigation of the association among ADHD, tic disorder, and allergic diseases.Results:  Patients with dual diagnoses of ADHD and tic disorder had a significantly higher prevalence of allergic diseases and psychiatric comorbidities, including allergic rhinitis (43% vs. 28.4% vs. 33.6% vs. 19.7%, p < 0.001), asthma (27.5% vs. 17.2% vs. 18.2% vs. 11.9%, p < 0.001), atopic dermatitis (10.6% vs. 8.4% vs. 7.0 vs. 5.9%, p < 0.001), allergic conjunctivitis (55.6% vs. 34.7% vs. 43.5% vs. 26.3%, p < 0.001), obsessive compulsive disorder (4.0% vs. 1.3% vs. 2.0% vs. 0.1%, p < 0.001), and anxiety disorder (22.1% vs. 18.0% vs. 6.0% vs. 0.5%, p < 0.001) than the ADHD alone group, the tic alone group, and the control group. Furthermore, ADHD patients with more allergic diseases (≥3 comorbidities: OR: 3.73, 95% CI: 2.65∼5.25; 2 comorbidities: OR: 2.52, 95% CI: 1.82∼3.47; 1 comorbidity: OR: 1.87, 95% CI: 1.41∼2.49) exhibited an increased risk of tic disorder compared with ADHD patients without allergic disease.Conclusion:  A significant association among ADHD, tic disorder, and allergic diseases was noted in our study. The results may inspire further studies to clarify the underlying mechanisms and help us understand more about the complex etiology of ADHD, tic disorder, and their co‐occurrence.
Phytophthora cinnamomi Associated with Root and Crown Rot of Walnut in Turkey
Authors: Kurbetlİ İlker 
Published: November 2012

AbstractWalnut decline caused by Phytophthora sp. occurred in an orchard in Sakarya province in Turkey. Affected young trees showed poor growth, leaf discolouration, root and crown rot and eventual death. A Phytophthora sp. isolated from necrotic taproots and crown tissues. The causal agent of the disease was identified as Phytophthora cinnamomi by morphological characteristics and comparing sequences of internal transcribed spacer (ITS) region. Upon conducting pathogenicity test, averaging 7.8‐cm‐long canker developed on basal stem within 2 weeks, while no cankers developed in the control plants.
Melatonin reduces median nerve injury‐induced mechanical hypersensitivity via inhibition of microglial p38 mitogen‐activated protein kinase activation in rat cuneate nucleus
Authors: Chiang Rayleigh Ping‐Ying , Huang Chun‐Ta , Tsai Yi‐Ju 
Published: November 2012

AbstractIn this study, we examined the relationships between p38 mitogen‐activated protein kinase (MAPK) activation in the cuneate nucleus (CN) and behavioral hypersensitivity after chronic constriction injury (CCI) of the median nerve. We further investigated effects of melatonin administration and pinealectomy on p38 MAPK activation and development of hypersensitivity. Using immunohistochemistry and immunoblotting, low levels of phosphorylated p38 (p‐p38) MAPK were detected in CN of normal rats. As early as 1 day after CCI, p‐p38 MAPK levels in the ipsilateral CN were significantly increased (1.4 ± 0.2‐fold, P < 0.05), which reached a maximum at 7 days (5.1 ± 0.4‐fold, P < 0.001). Double immunofluorescence labeling with cell‐specific markers showed that p‐p38 MAPK immunoreactive cells co‐expressed OX‐42, a microglia activation maker, suggesting the expression of p‐p38 MAPK in microglia. Microinjection of SB203580, a p38 MAPK inhibitor, into the CN 1 day after CCI attenuated injury‐induced behavioral hypersensitivity in a dose‐dependent manner. Furthermore, animals received melatonin treatment at daily doses of 37.5, 75, 150, or 300 mg/kg from 30 min before until 3 days after CCI. Melatonin treatment dose‐dependently attenuated p‐p38 MAPK levels, release of pro‐inflammatory cytokines, and behavioral hypersensitivity following CCI; conversely, pinealectomy that resulted in a reduction in endogenous melatonin levels exacerbated these effects. In conclusion, median nerve injury‐induced microglial p38 MAPK activation in the CN modulated development of behavioral hypersensitivity. Melatonin supplementation eased neuropathic pain via inhibition of p38 MAPK signaling pathway; contrarily, reducing endogenous blood melatonin levels by pinealectomy promoted phosphorylation of p38 MAPK and made rats more vulnerable to nerve injury‐induced neuropathic pain.
Association of subgingival colonization of Candida albicans and other yeasts with severity of chronic periodontitis
Authors: Canabarro A. , Valle C. , Farias M. R. , Santos F. B. , Lazera M. , Wanke B. 
Published: November 2012

Background and ObjectiveThe aim of this study is to analyze the relationship between the subgingival colonization by Candida albicans and other yeasts with the severity of chronic periodontitis (CP).Material and MethodsAfter sample size calculation, 40 patients with CP and 20 healthy subjects (HS) were included in the study. Cases of slight‐moderate (MCP, n = 23) and severe CP (SCP, n = 17) were defined according to the Centers for Disease Control/American Association of Periodontology classification. Subgingival samples were acquired using sterile paper‐points from the sulcus or the deepest periodontal pocket of each healthy and subject with CP, respectively, and were cultured aerobically on three selective media. Yeast colonies that grew on the surface of plates were later identified by biochemical reactions. Statistical tests were used to analyze the association between subgingival yeast colonization (number of yeast‐positive individuals and colony forming units (CFU) per subject) and periodontal disease status, considering statistical significance when P < 0.05.ResultsAlthough several yeast species were found (C. parapisilosis, Rhodotorula sp., C. dubliniensis and C. tropicalis), only C. albicans was present in all the patients with yeast‐positive CP. Twelve patients (30%) with CP presented yeasts in the subgingival biofilm while only three patients (15%) in the HS group were positive for these microorganisms. No statistical difference was found between the CP and HS groups (P = 0.084). However, when the CP group was divided on the basis of severity, statistical differences were observed between the SCP and MCP groups (47% vs. 17%, P = 0.043), and between the SCP and HS groups (47% vs. 15%, P = 0.033). No statistical difference was observed between the MCP and HS groups (17% vs. 15%, P = 0.832). High densities of yeasts were found only in patients with MCP and SCP (mean and range 61.25 (0–100) CFU/plate and mean and range 51 (0–101) CFU/plate, respectively).ConclusionIn this group of patients, subgingival colonization of some yeasts, especially C. albicans, was associated with the severity of CP.
Engineering secondary cell wall deposition in plants
Authors: Yang Fan , Mitra Prajakta , Zhang Ling , Prak Lina , Verhertbruggen Yves , Kim Jin‐Sun , Sun Lan , Zheng Kejian , Tang Kexuan , Auer Manfred , Scheller Henrik V. , Loqué Dominique 
Published: November 2012

SummaryLignocellulosic biomass was used for thousands of years as animal feed and is now considered a great sugar source for biofuels production. It is composed mostly of secondary cell walls built with polysaccharide polymers that are embedded in lignin to reinforce the cell wall structure and maintain its integrity. Lignin is the primary material responsible for biomass recalcitrance to enzymatic hydrolysis. During plant development, deep reductions of lignin cause growth defects and often correlate with the loss of vessel integrity that adversely affects water and nutrient transport in plants. The work presented here describes a new approach to decrease lignin content while preventing vessel collapse and introduces a new strategy to boost transcription factor expression in native tissues. We used synthetic biology tools in Arabidopsis to rewire the secondary cell network by changing promoter‐coding sequence associations. The result was a reduction in lignin and an increase in polysaccharide depositions in fibre cells. The promoter of a key lignin gene, C4H, was replaced by the vessel‐specific promoter of transcription factor VND6. This rewired lignin biosynthesis specifically for vessel formation while disconnecting C4H expression from the fibre regulatory network. Secondly, the promoter of the IRX8 gene, secondary cell wall glycosyltransferase, was used to express a new copy of the fibre transcription factor NST1, and as the IRX8 promoter is induced by NST1, this also created an artificial positive feedback loop (APFL). The combination of strategies—lignin rewiring with APFL insertion—enhances polysaccharide deposition in stems without over‐lignifying them, resulting in higher sugar yields after enzymatic hydrolysis.
Interpersonal Trust Consistency and the Quality of Peer Relationships During Childhood
Authors: Rotenberg Ken J. , Boulton Michael 
Published: November 2012

AbstractFive hundred five children (267 female) enrolled in school years 5 and 6 in the UK (M = 9 years and 9 months) completed measures of trust beliefs in peers, best friendships, ascriptions of trustworthiness, and trustworthiness toward peers. Children's social disengagement, peer preference, and peer victimization were assessed by sociometric ratings. It was found that, relative to children with consistent trust beliefs and trustworthiness, and those with inconsistent low trust beliefs and high trustworthiness, children with high trust beliefs in peers and low trustworthiness toward peers showed (1) low reciprocity of trustworthiness as assessed by disparity in ascribed trustworthiness between best friends, (2) low quality of peer relationships in the form of low peer preference and high peer victimization, and (3) high social disengagement. The findings supported the basis, domain, and target interpersonal trust framework (Rotenberg) as an account of the relation between children's interpersonal trust consistency and quality of peer relationships.
Pig‐to‐human xenotransplantation summit in Changsha, China
Authors: Cooper David K. C. , Schuurman Henk‐Jan 
Published: November 2012

Cooper DKC, Schuurman H‐J. Pig‐to‐human xenotransplantation summit in Changsha, China. Xenotransplantation 2012; 19: 327–328. © 2012 John Wiley & Sons A/S.Abstract:  On August 18 to 19, 2012, a meeting “Pig‐to‐Human Xenotransplantation Summit” was held in Changsha, Hunan, China, by Dr. Wei Wang. This summit highlighted important progress in the field in China. We here present a report from this meeting.
Genome Sequence of Halorubrum sp. Strain T3, an Extremely Halophilic Archaeon Harboring a Virus-Like Element
Authors: Chen Shaoxing , Wang Chuanming , Zhao Zhiwei , Yang Zhu L. 
Published: November 2012

ABSTRACT

Halorubrum
sp. strain T3, harboring a virus-like element, was isolated from a sample collected from a solar saltern in Yunnan, China. Several strains of
Halorubrum
pleomorphic viruses were reported in this genus recently; however, the virus-host interaction in haloarchaea remains unclear. To explore this issue, here we present the genome sequence of
Halorubrum
sp. strain T3 (3,168,011 bp, 68.48% G+C content).
Draft Genome Sequence of Actinobacillus pleuropneumoniae Serotype 7 Strain S-8
Authors: Li Gang , Xie Fang , Zhang Yanhe , Wang Chunlai 
Published: November 2012

ABSTRACT

The Gram-negative bacterium
Actinobacillus pleuropneumoniae
is the etiological agent of porcine pleuropneumonia, a respiratory disease that leads to severe economic losses in the swine industry. For years, scientists working with it have lacked a reliable genome sequence for comparison with other
Actinobacillus
species. Here, we report the draft genome sequence of
A. pleuropneumoniae
serotype 7 (strain S-8), isolated from swine lung in China in 1992.
Draft Genome Sequence of the Antifungal-Producing Plant-Benefiting Bacterium Burkholderia pyrrocinia CH-67
Authors: Song Ju Yeon , Kwak Min-Jung , Lee Kwang Youll , Kong Hyun Gi , Kim Byung Kwon , Kwon Soon-Kyeong , Lee Seon-Woo , Kim Jihyun F. 
Published: November 2012

ABSTRACT

Burkholderia pyrrocinia
CH-67 was isolated from forest soil as a biocontrol agent to be utilized in agriculture. Here, we report the 8.05-Mb draft genome sequence of this bacterium. Its genome contains genes involved in biosynthesis of secondary metabolites and plant growth promotion, which may contribute to probiotic effects on plants.
Complete Genome Sequence of Brucella abortus 134, a Biovar 1 Strain Isolated from Human
Authors: Wang Yufei , Ke Yuehua , Gao Guangjun , Zhen Qing , Yuan Xitong , Wang Zhoujia , Xu Jie , Li Tiefeng , Wang Dali , Huang Liuyu , Xu Xingran , Chen Zeliang 
Published: November 2012

ABSTRACT

Brucella abortus
is one of the common pathogens causing brucellosis in China. Here, we report the genome sequence of
B. abortus
strain 134, a strain isolated from a human patient and belonging to biovar 1, the most highly represented biovar among
B. abortu
s strains in China.
General Features of Squall Lines in East China
Authors: Meng Zhiyong , Yan Dachun , Zhang Yunji 
Published: November 2012

Abstract
Based on mosaics of composite radar reflectivity patterns during the 2-yr period of 2008–09, a total of 96 squall lines were identified in east China with a maximum frequency of occurrence in north China near the boundaries between Shandong, Henan, Anhui, and Jiangsu Provinces. The squall lines form from March to October with a peak in July. Their diurnal variation shows a major peak in the early evening and two minor peaks in the early morning and early afternoon. The time between squall-line formation and the first echo is about 4.8 h. The squall lines have a dominant southwest–northeast orientation, an eastward motion at a speed of 14.4 m s−1, a maximum length of 243 km, a maximum intensity of 58–63 dBZ, and a duration of 4.7 h on average. The squall lines commonly form in a broken-line mode, display a trailing-stratiform pattern, and dissipate in a reversed broken-line mode. Composite rawinsonde analyses show that squall lines in midlatitude east China tend to form in a moister environment with comparable background instability, and weaker vertical shear relative to their U.S. counterparts. The rawinsondes were also composited with respect to different formation and organizational modes. The environmental flows of the squall lines in the area with high frequency of formation were classified into six synoptic weather patterns: pre–short trough, pre–long trough, cold vortex, subtropical high, tropical cyclone (TC), and posttrough. About one-third of the squall lines form in the dominant pre-short-trough pattern. Favorable conditions of various patterns were examined in terms of moisture supply, instability, vertical wind shear, low-level jet, etc.
Forecasting Drought Using the Agricultural Reference Index for Drought (ARID): A Case Study
Authors: Woli Prem , Jones James , Ingram Keith , Paz Joel 
Published: November 2012

AbstractDrought forecasting can aid in developing mitigation strategies and minimizing economic losses. Drought may be forecast using a drought index, which is an indicator of drought. The agricultural reference index for drought (ARID) was used as a tool to investigate the possibility of using climate indices (CIs) as predictors to improve the current level of forecasting, which is El Niño–Southern Oscillation (ENSO) based. The performances of models that are based on linear regression (LR), artificial neural networks (ANN), adaptive neuron-fuzzy inference systems (ANFIS), and autoregressive moving averages (ARMA) models were compared with that of the ENSO approach. Monthly values of ARID spanning 56 yr were computed for five locations in the southeastern United States, and monthly values of the CIs having significant connections with weather in this region were obtained. For the ENSO approach, the ARID values were separated into three ENSO phases and averaged by phase. For the ARMA models, monthly time series of ARID were used. For the ANFIS, ANN, and LR models, ARID was predicted 1, 2, and 3 months ahead using the past values of the first principal component of the CIs. Model performances were assessed with the Nash–Sutcliffe index. Results indicated that drought forecasting could be improved for the southern part of the region using ANN models and CIs. The ANN outperformed the other models for most locations in the region. The CI-based models and the ENSO approach performed better during the winter, whereas the efficiency of ARMA models depended on precipitation periodicities. All models performed better for southern locations. The CIs showed good potential for use in forecasting drought, especially for southern locations in the winter.
Evaluation of a Wind-Wave System for Ensemble Tropical Cyclone Wave Forecasting. Part II: Waves
Authors: Lazarus Steven M. , Wilson Samuel T. , Splitt Michael E. , Zarillo Gary A. 
Published: November 2012

Abstract
A wind-wave forecast system, designed with the intention of generating unbiased ensemble wave forecasts for extreme wind events, is assessed. Wave hindcasts for 12 tropical cyclones (TCs) are forced using a wind analysis produced from a combination of the North American Regional Reanalysis (NARR) and a parametric wind model. The default drag parameterization is replaced by one that is more in line with recent studies where a cap at weak-to-moderate wind speeds is applied. Quadrant-based significant wave height (Hs) statistics are composited in a storm-relative reference frame and stratified by the radius of maximum wind, storm speed, and storm intensity. Improvements in Hs are gleaned from both downscaling the NARR winds and tuning the wave model. However, the paradigm whereby the drag coefficient depends solely on the wind speed is limiting. Results indicate that Hs is biased low in the right quadrants (for all statistical subcategories). Conversely, Hs is high biased in the left-rear quadrant even though the analysis wind field is underforecast there. At radii less than 100 nautical miles, the model peak wave direction is offset from the observed, with the model (buoy) peak more in line with (to the left of) the direction of the tropical cyclone motion. As a result, the predominant storm-relative wind direction, which is northwesterly in the left-rear quadrant, opposes that of the buoy peak wave direction, while the model peak is more crosswise with respect to the wind. This will likely reduce the magnitude of the wind stress in the model.
‘The Bad Enough Group Analyst’: Authenticity and Emotional Responsiveness in Group Analysis’. A Response to Farhad Dalal’s Foulkes Lecture
Authors: Berman Avi 
Published: November 2012

The group can be a moral place only if it can contain moral challenges. For this, the group needs a sort of freedom to relate in which the group can move between poles of injury and regret, and between impassivity on the one hand and concern on the other. The emotional involvement of the all members with each other is a pre-condition for the ethical situation of the group. Emotional responsiveness entails authenticity. The authentic expression is spontaneous and unexpected (Nitsun, 1996). Sometimes it is impulsive, emotional, enacted and surprising. It can break through blockages of withholding. An authentic expression can be loving or hurtful. In group analytic psychotherapy, it is not only the excessive responsiveness of the therapist to the weakness and the suffering of the members which is the therapeutic factor. When each member is attuned to himself and to the other, the group fulfils its most important therapeutic quality. In this article I suggest that in order to develop these strengths the therapist must be able to be a ‘bad enough’ therapist with the group members. It would be better to claim that therapist non-responsiveness is necessary for the formation of the group, as a body which gives meaning to each one of the participants. In a certain way it invites each of the members to be present and in another way it creates a situation in which the members are nearly forced to be present through the responsiveness of each of them in the lack of a satisfactory individual response of the conductor. I suggest that the analyst’s authentic response corresponds with what Dr. Dalal calls ‘emotional responsiveness’. This is in fact the ‘bad enough participation’ on the part of the analyst, which leads to a breakthrough in the therapy. The morality of the therapist is expressed in his willingness to move from the neutral analytic position and see himself as a reason for part of what is going on in the group.