bluuebunny/crossref_metadata_2025_split huggingface dataset:
Modeling of Dimensional Changes and Residual Stresses After Transformation-Free Cooling
Authors: Landek Darko , Lisjak Dragutin , Lübben Thomas , Župan Josip 
Published: June 2014

Abstract
Predicting thermal distortions and residual stresses after steel heat treatment is a complex task in which the solution involves the use of a number of process parameters and nonlinear variation of steel properties. Former investigations in transformation-free cooling processes of long cylindrical work pieces in a gas nozzle field showed a typical behavior of the dimensional changes which indicated the possibility of introducing dimensionless numbers to predict thermal distortions. It was found that the changes in the dimensions of cylinders correlate well with only a few dimensionless numbers which are defined as function of shape and dimensions of components, its initial temperature, temperature of the quenching media, heat transfer coefficient, heat conductivity, heat capacity, density, thermal expansion coefficient, Young's modulus, Poisson's ratio, yield strength, and strain hardening behavior. For a systematic investigation of impacts on dimensional changes and residual stresses after transformation-free cooling, a representative group of 28 austenitic stainless steels was selected from literature. Their properties were statistically analyzed and three representative combinations of steel properties have been selected. The numerical simulations were carried out by use of the commercial finite element (FE) program SYSWELD 2005 with the aim to predict residual stresses and change of dimensions of a long cylinder made of austenitic stainless steel after gas cooling from the high temperature down to room temperature. The FE results were analyzed with the nonlinear regression methods and with genetic programming methods. From these analyses, two dimensionless mathematical models were proposed, one for prediction of thermal distortions and the other for prediction of equivalent residual stresses. The proposed dimensionless regression models allow the portability of the calculation results to similar cooling conditions (temperature independent heat transfer) for a transformation-free cooling of long cylinders made from any austenitic steel selected from the considered representative group of steels.
Prion permissive pathways: extracellular matrix genes control susceptibility to prion infection
Authors: Imberdis Thibaut , Harris David A 
Published: June 2014

There are wide variations in the susceptibility of humans, animals, and cultured cell lines to infection by prions. In this issue of The EMBO Journal, Marbiah et al () identified a gene regulatory network that regulates the susceptibility of cultured cells to prion infection. Surprisingly, a number of these genes impact the structure of the extracellular matrix. These results have important implications for understanding mechanisms of prion infection and also suggest new therapeutic targets.
Not an inside job: non‐coded amino acids compromise the genetic code
Authors: Ribas de Pouplana Lluís 
Published: June 2014

The sophistication of the editing mechanisms that prevent gene translation errors indicates that amino acid misincorporation is generally a problem to be avoided. Mistranslation is considered invariably deleterious and often caused by confusion between similar proteogenic amino acids. These views are being challenged. The evidence linking misincorporation of dietary non‐proteogenic amino acids to human disease continues to grow, and a report in this issue of The EMBO Journal demonstrates the importance of preventing non‐proteogenic amino acid misincorporation for cellular homeostasis (Cvetesic et al, ).
Epidermal p65/NF‐κB signalling is essential for skin carcinogenesis
Authors: Kim Chun , Pasparakis Manolis 
Published: June 2014

AbstractThe nuclear factor kappa B (NF‐κB) signalling pathway exhibits both tumour‐promoting and tumour‐suppressing functions in different tissues and models of carcinogenesis. In particular in epidermal keratinocytes, NF‐κB signalling was reported to exert primarily growth inhibitory and tumour‐suppressing functions. Here, we show that mice with keratinocyte‐restricted p65/RelA deficiency were resistant to 7, 12‐dimethylbenz(a)anthracene (DMBA)‐/12‐O‐tetra decanoylphorbol‐13 acetate (TPA)‐induced skin carcinogenesis. p65 deficiency sensitized epidermal keratinocytes to DNA damage‐induced death in vivo and in vitro, suggesting that inhibition of p65‐dependent prosurvival functions prevented tumour initiation by facilitating the elimination of cells carrying damaged DNA. In addition, lack of p65 strongly inhibited TPA‐induced epidermal hyperplasia and skin inflammation by suppressing the expression of proinflammatory cytokines and chemokines by epidermal keratinocytes. Therefore, p65‐dependent NF‐κB signalling in keratinocytes promotes DMBA‐/TPA‐induced skin carcinogenesis by protecting keratinocytes from DNA damage‐induced death and facilitating the establishment of a tumour‐nurturing proinflammatory microenvironment.
Contrast-Enhanced and Time-of-Flight MR Angiographic Assessment of Endovascular Coiled Intracranial Aneurysms at 1.5 T
Authors: Levent Akin , Yuce Ihsan , Eren Suat , Ozyigit Omer , Kantarci Mecit 
Published: June 2014

This study evaluated contrast-enhanced magnetic resonance angiography (CE-MRA) and three-dimensional time-of-flight magnetic resonance angiography (3D-TOF-MRA) through comparisons with digital subtraction angiography (DSA) for the follow-up of intracranial aneurysms treated with detachable coils. Sixty-seven patients with 79 aneurysms underwent 3D-TOF-MRA, CE-MRA, and catheter angiography one year after coiling. Two independent observers classified recanalization status on images as neck or body remnant or no recanalization. For 3D-TOF-MRA and CE-MRA, the intermodality agreement, interobserver agreement, and correlation with angiography were assessed. Sixty-seven patients with 79 coiled aneurysms agreed to participate in the study. Three aneurysms could not be detected on 3D-TOF-MRA, so they were excluded from this study. Interobserver agreement was very good for 3D-TOF-MRA and CE-MRA (kappa (κ): 0.87, 0.94, respectively). Correlation of TOF-MRA with angiography was good (κ: 0.76). Correlation of CE-MRA with angiography was excellent (κ: 0.91). The sensitivity and specificity of TOF-MRA were 92% and 98%, respectively. The sensitivity and specificity of CE-MRA were 96% and 98%, respectively. After selective embolization of intracranial aneurysms, CE-MRA is useful and comparable to DSA in the assessment of aneurysmal recanalization. Agreement with the gold standard is stronger with CE-MRA than with 3D-TOF-MRA.
PASEDHULURAN AS A SOCIAL CAPITAL FOR LOCAL ECONOMIC DEVELOPMENT: EVIDENCE FROM POTTERY VILLAGE
Authors: Karmilah Mila , Nuryanti Wiendu , Soewarno Nindyo , Setiawan Bakti 
Published: June 2014

The increase in both industrialization and tourism in Kasongan village famous with its pottery being the tourism Village since 1988, radically altered the local economy and domestic life. Based on oral history, survey, and documentary sources, this paper examine the impact of economics globalization to the diversity of culture in Kasongan. Globalization has two faces. If it can be managed properly, globalization can certainly give sufficient benefit to the country. The result of study indicated that pasedhuluran kinship systems in pottery production chain as one of social capital in socio-economic development in Kasongan, play an important role. This can be seen in terms of hiring local labor, then the pottery associated with the ordering system, and the use of the showroom to promote their pottery. Based on this note that the negative impact of globalization, especially the pottery in Kasongan indsutry can be minimized by pasedhuluran system. Peningkatan industrialisasi dan pariwisata di Desa Kasongan yang terkenal dengan kerajinan gerabah yang telah berkembang sejak tahun 1972 dan menjadi desa wisata pada tahun 1988, secara radikal telah mengubah ekonomi lokal dan kehidupan masyarakat di desa tersebut. Berdasarkan wawancara terkait sejarah, survei, dan sumber-sumber dokumenter lainnya, maka tulisan ini akan mengkaji dampak globalisasi ekonomi terhadap keragaman budaya masyarakat setempat. Globalisasi memiliki dua sisi. Jika globalisasi dapat dikelola dengan baik, maka globalisasi dapat memberikan manfaat yang cukup baik bagi negara. Namun, jika suatu negara tidak dapat beradaptasi dan menentukan strategi yang perlu diterapkan dalam rangka menghadapi globalisasi, negara akan menjadi korban dari globalisasi. Hasil penelitian menunjukkan bahwa pasedhuluran adalah sistem kekerabatan di rantai produksi kegiatan produksi gerabah. Pasedhuluran sebagai salah satu modal sosial dalam pembangunan sosial-ekonomi di Kasongan, memainkan peranan yang penting. Hal ini terlihat dalam sistem tenaga kerja, dimana sebagian besar merupakan keluarga. Selain sistem tenaga kerja pasedhulran juga terlihat pada sistem pemesanan (order gerabah), dan menggunakan showroom sebagai tempat mempromosikan gerabah mereka. Berdasarkan studi ini diketahui bahwa dampak globalisasi dapat diminimalisir dengan adanya sistem kekerabatan (pasedhuluran).
KONTESTASI DISKURSUS KETAHANAN PANGAN DAN PEMBENTUKAN KUASA PENGETAHUAN PEREMPUAN PADA KELUARGA PETANI SAWAH DI SUMATERA SELATAN
Authors: - Yunindyawati , Sumarti Titik , Adiwibowo Soeryo , Vitayala S. Hubbeis Aida , - Hardinsyah 
Published: June 2014

Tulisan ini bertujuan untuk mengkaji diskursus ketahanan pangan antaraktor dan pembentukan kuasa pengetahuan perempuan pada keluarga petani sawah lebak di Kecamatan Pemulutan Selatan kabupaten Ogan Ilir Sumatera Selatan. Metode yang digunakan adalah metode kualitatif dengan menggunakan paradigma konstruktivistik. Hasil penelitian ini menunjukkan bahwa terdapat tiga aktor utama dalam diskursus ketahanan pangan yakni pemerintah, komunitas dan pelaku usaha. Masing-masing aktor berupaya mempraktikkan diskursusnya pada keluarga petani. Pada saat mempraktikkan diskursus terjadi interaksi diskursus antaraktor yang bersifat sinergis. Namun diskursus yang paling dominan dipraktikkan oleh keluarga adalah diskursus komunitas, sementara diskursus pemerintah sebagai pelengkap dan diskursus pelaku usaha sebagai pendorong. Pembentukan kuasa pengetahuan perempuan oleh para aktor bersifat elastis dan terdapat perbedaan akses dalam pembentukan kuasa pengetahuan perempuan berdasarkan perbedaan kelas sosial. This study was to examine food security discourse between actors in the farmers family and the formation of the power of women’s knowledge. The method used was a qualitative method using constructivism paradigm. Research findings indicate that there were three main actors in the discourse of food security namely the government, community and business. Each attempt to practice their discourse on family farmers. It turns out that in practice this discourse, there were interaction between actors in synergy. But the most dominant discourse was discourse of community that practiced by the family while the government discourse as a supplement and entrepreneurs discourse as a spur. Formation of the power of women’s knowledge by actors were flexibles/elastics and there were differences acces of formation in power of women’s knowledge between women in different social classes
Literacy Promotion: An Essential Component of Primary Care Pediatric Practice
Authors:   COUNCIL ON EARLY CHILDHOOD, High Pamela C. , Klass Perri , Donoghue Elaine , Glassy Danette , DelConte Beth , Earls Marian , Lieser Dina , McFadden Terri , Mendelsohn Alan , Scholer Seth , Schulte Elaine E. , Takagishi Jennifer , Vanderbilt Douglas , Williams P. Gail 
Published: June 2014

This Policy Statement was revised. See https://doi.org/10.1542/peds.2024-069090.
Reading regularly with young children stimulates optimal patterns of brain development and strengthens parent-child relationships at a critical time in child development, which, in turn, builds language, literacy, and social-emotional skills that last a lifetime. Pediatric providers have a unique opportunity to encourage parents to engage in this important and enjoyable activity with their children beginning in infancy. Research has revealed that parents listen and children learn as a result of literacy promotion by pediatricians, which provides a practical and evidence-based opportunity to support early brain development in primary care practice. The American Academy of Pediatrics (AAP) recommends that pediatric providers promote early literacy development for children beginning in infancy and continuing at least until the age of kindergarten entry by (1) advising all parents that reading aloud with young children can enhance parent-child relationships and prepare young minds to learn language and early literacy skills; (2) counseling all parents about developmentally appropriate shared-reading activities that are enjoyable for children and their parents and offer language-rich exposure to books, pictures, and the written word; (3) providing developmentally appropriate books given at health supervision visits for all high-risk, low-income young children; (4) using a robust spectrum of options to support and promote these efforts; and (5) partnering with other child advocates to influence national messaging and policies that support and promote these key early shared-reading experiences. The AAP supports federal and state funding for children’s books to be provided at pediatric health supervision visits to children at high risk living at or near the poverty threshold and the integration of literacy promotion, an essential component of pediatric primary care, into pediatric resident education. This policy statement is supported by the AAP technical report “School Readiness” and supports the AAP policy statement “Early Childhood Adversity, Toxic Stress, and the Role of the Pediatrician: Translating Developmental Science Into Lifelong Health.”
Catecholamine Metabolites in Urine, as Chronic Stress Biomarkers, Are Associated With Higher Risk of Chronic Periodontitis in Adults
Authors: Mesa Francisco , Magán‐Fernández Antonio , Muñoz Ricardo , Papay‐Ramírez Lara , Poyatos Rafael , Sánchez‐Fernández Elena , Galindo‐Moreno Pablo , Rodríguez‐Barranco Miguel 
Published: June 2014

Background: The purpose of this case–control study is to investigate the association between stress and periodontitis by determining stress biomarkers in saliva and urine and to determine whether oral hygiene, gingival inflammation, and tooth loss are correlated with stress biomarkers in patients with periodontitis.Methods: A total of 77 patients (41 cases [with periodontitis] and 36 controls) participated in this study. Periodontal examination findings included probing depth, clinical attachment loss, bleeding on probing (BOP), plaque index (PI), and tooth loss. Secretory immunoglobulin (sIg)A and cortisol were determined in saliva. Cortisol, creatinine‐adjusted cortisol, metanephrine, normetanephrine, and total metanephrines were measured in urine.Results: Urinary metanephrine (P = 0.013) and total metanephrine (P = 0.023) levels were higher in the case group. In cases, salivary cortisol was correlated with PI (r = 0.464, P <0.01), BOP (r = 0.401, P <0.05), and tooth loss (r = 0.245, P <0.05). Urinary metanephrine levels above the median were associated with a 3.4‐fold higher risk of periodontitis (95% confidence interval [CI] = 1.1 to 10.2; P = 0.029), with an 82% increase in risk for each increment of 0.05 µg/24 hours. Urinary total metanephrine levels above the median were associated with a five‐fold higher risk of periodontitis (95% CI = 1.6 to 15.7; P = 0.006).Conclusions: The present results offer new evidence of the association between urinary concentrations of catecholamine metabolites (metanephrine and total metanephrines) and chronic periodontitis. Salivary IgA level showed no statistical difference between the cases and controls. Salivary cortisol levels in the patients with periodontitis were correlated with worse PI, higher gingival inflammation, and greater tooth loss.
Pay Convexity, Earnings Manipulation, and Project Continuation
Authors: Laux Volker 
Published: June 2014

ABSTRACT
This paper studies the optimal design of long-term executive pay plans when boards of directors use accounting information for investment decision-making and executives can take costly actions to manipulate this information. The model predicts that a shift to more convex executive pay plans, such as equity plans that rely more on options and less on stock, is associated with higher levels of manipulation, lower reporting quality, and less efficient investment. When designing the optimal contract, the board trades off these effects with the cost of inducing executive effort. The paper also analyzes how the optimal pay convexity and the equilibrium level of manipulation change when the CEO's opportunistic reporting discretion changes. The model predicts that an increase in the CEO's marginal cost of manipulation increases the optimal level of pay convexity and first increases and then decreases the magnitude of manipulation.
JEL Classifications: M12; M41; G31.
Design and Evaluation of a Continuous Data Level Auditing System
Authors: Kogan Alexander , Alles Michael G. , Vasarhelyi Miklos A. , Wu Jia 
Published: June 2014

SUMMARY:
This study develops a framework for a continuous data level auditing system and uses a large sample of procurement data from a major health care provider to simulate an implementation of this framework. In this framework, the first layer monitors compliance with deterministic business process rules and the second layer consists of analytical monitoring of business processes. A distinction is made between exceptions identified by the first layer and anomalies identified by the second one. The unique capability of continuous auditing to investigate (and possibly remediate) the identified anomalies in “pseudo-real time” (e.g., on a daily basis) is simulated and evaluated. Overall, evidence is provided that continuous auditing of complete population data can lead to superior results, but only when audit practices change to reflect the new reality of data availability.
Data Availability: The data are proprietary. Please contact the authors for details.
Voluntary Disclosure, Legal Institutions, and Firm Valuation: Evidence from U.S. Cross-Listed Foreign Firms
Authors: Shi Yaqi , Kim Jeong-Bon , Magnan Michel L. 
Published: June 2014

ABSTRACT
Building on the bonding hypothesis, this paper examines the economic consequences of voluntary management earnings forecasts (MFs) made by foreign firms cross-listed in the U.S. market. Our work reveals the following. First, cross-listed firms that voluntarily issue MFs exhibit higher firm valuation (Tobin's Q) than those that do not issue MFs, with forecast precision and frequency further enhancing valuation premiums. Additionally, the valuation premium of MFs is more pronounced for cross-listed firms than for a matched sample of U.S. domestic firms. Second, cross-listed firms from countries with weaker legal regimes are valued more for their voluntary forecasts relative to those from stronger legal regimes. Third, further sensitivity analyses suggest that valuation implications from MFs are more consistent with reputational bonding than with a signaling perspective. Finally, our mediation analysis suggests that voluntary disclosures of MFs are an important channel through which the information environment positively influences firm valuation. Overall, our study contributes to both the voluntary disclosure and cross-listing literatures.
JEL Classifications: G14; G15; G32; G34; M41.
Proactive Transfer Pricing Risk Management in PATA Countries
Authors: Borkowski Susan C. , Gaffney Mary Anne 
Published: June 2014

ABSTRACT
Transnational corporations (TNCs) have long considered transfer pricing as a key tax concern. If stability in transfer pricing is a necessary condition for dynamic cross-border trading, then recent financial reporting changes, updated transfer pricing guidelines, and new reporting requirements for uncertain tax positions are destabilizing influences that must be addressed by companies in order to mitigate their transfer pricing-related exposures and risk. This study reports the results of a survey of tax executives from the four countries comprising the Pacific Association of Tax Administrators (PATA), three of which have transfer pricing regulations based on Organisation for Economic Co-operation and Development (OECD) guidelines. The study seeks to explain how TNCs are managing their transfer pricing risks proactively in today's volatile environment, and if their actions are successful. Findings include contradictory evidence regarding audit risk reduction strategies recommended by tax authorities and the utility of those strategies in actually reducing corporate audit risk. These were surprising results, given that tax authorities and transfer pricing consulting firms tout certain transfer pricing agreements as the best way to mitigate transfer pricing audit risk. At best, are these agreements neutral relative to audit risk? At worst, are tax authorities using these agreements as a source of confidential data for possible future use in both transfer pricing and non-transfer pricing audits?
Color Stability of Resin Used for Caries Infiltration After Exposure to Different Staining Solutions
Authors: Borges AB , Caneppele TMF , Luz M , Pucci CR , Torres CRG 
Published: June 2014

SUMMARY

Purpose
The aim of this study was to investigate the staining behavior of demineralized enamel infiltrated by low-viscosity resin.

Methods and Materials
Bovine enamel/dentin cylindrical samples (3 × 2 mm) were assigned into four groups (n=45) according to the enamel treatment: sound enamel (control), demineralization + artificial saliva, demineralization + daily application of 0.05% NaF, demineralization + resin infiltration (Icon, DMG). Artificial white spot lesions were produced in groups with demineralization. After the treatments, color was assessed by spectrophotometry, using the CIE L*a*b* system. The specimens (n=15) were then immersed in deionized water, red wine, or coffee for 10 minutes daily for eight days. Color was measured again, and the specimens were repolished with sandpaper discs. The final color was assessed. Data were analyzed by two-way analysis of variance and Tukey tests (α=0.05). A paired t-test was used for comparison between staining and repolishing conditions.

Results
There were significant differences for surface treatment and dye after staining and repolishing. Immersion in wine and coffee resulted in significantly increased color alteration (ΔE) compared with water (p=0.001). The resin-infiltrated group exhibited the highest staining values (p=0.001). The repolishing procedures resulted in significantly decreased color change.

Conclusion
The exposure of specimens to colored solutions resulted in significant color alteration. The demineralized enamel treated with resin infiltration showed significantly higher staining than all other tested groups; however, the repolishing of the specimens minimized the staining effect.