bluuebunny/crossref_metadata_2025_split huggingface dataset:
Grain Breakup During Elevated Temperature Deformation of an HCP Metal
Authors: Honniball Peter D. , Preuss Michael , Rugg David , Quinta da Fonseca João 
Published: February 2015

AbstractA combination of mechanical testing, EBSD and crystal plasticity finite element modeling were used to investigate the influence of temperature on the fragmentation of grains in a zirconium alloy. The results demonstrate that grains of Zircaloy-4 fragment more as the temperature rises. This trend can be explained by an increasing difference between the CRSS values for 〈c+a〉 slip and 〈a〉 slip as temperature rises. This change in relative slip activities with temperature is supported by experimental observations of macroscopic anisotropy and in-grain misorientation axes calculated from EBSD data, as well as plasticity modeling. By tracking the microstructural evolution during deformation, it is shown that the two major texture components fragment to different degrees under the action of prismatic slip. Grains in the$$ \left\langle {11\overline{2} 0} \right\rangle $$112¯0fiber are significantly more stable than those in the$$ \left\langle {10\overline{1} 0} \right\rangle $$101¯0fiber, which break up. Grains of the latter fiber fragment heterogeneously as portions of the grain rotate in opposite directions, and some do not rotate at all.
In vitro fertilization embryo development from caffeine‐treated murine sperm
Authors: Yokota Yoshimasa , Yokota Hidemi , Yokota Mikako , Araki Yasuyuki , Araki Yasuhisa 
Published: February 2015

AbstractPurposeTo evaluate the effect of long‐term caffeine administration on murine sperm and subsequent in vitro fertilization (IVF).MethodsMale mice were injected with various doses (0, 0.2 and 1.0 mg/mouse/day) of caffeine for 1 month. After sperm collection, the IVF rate and embryo development to the blastocyst stage were evaluated.ResultsThe mean body weight significantly decreased in the 1.0 mg/day treatment group compared to the control group (P < 0.01). Testicular weight and histological features did not differ, and total blood testosterone was no different in spite of the difference between 0.2 and 1.0 mg/day of caffeine. The IVF rate differed significantly between the control group [100/105 (95.2 %)] and 0.2 mg/day group [106/121 (87.6 %)] (P < 0.05). Furthermore, blastocyst formation was significantly and dose‐dependently lower with higher caffeine levels: control group: 85/100 (85.0 %); 0.2 mg/day group: 84/106 (79.2 %) (P < 0.05); 1.0 mg/day group: 64/102 (62.7 %) (P < 0.001).ConclusionsCaffeine treatment affected body weight of male mice. However, testicular weight, histological features and total blood testosterone concentration were not statistically different. In addition, following IVF using sperm from these mice, blastocyst formation decreased in a dose‐dependent manner. These findings suggest that embryo development from oocytes fertilized with sperm from caffeine‐administered male mice is negatively affected.
Measures of circadian preference in childhood and adolescence: A review
Authors: Tonetti L. , Adan A. , Di Milia L. , Randler C. , Natale V. 
Published: February 2015

AbstractPurposeTo review the psychometric properties of the questionnaires commonly filled in by children and adolescents to measure circadian preference.MethodsWe examined the Morningness-Eveningness Questionnaire for Children and Adolescents (MEQ-CA), the Morningness-Eveningness Scale for Children (MESC) and the Composite Scale of Morningness (CSM). We critically analyzed the reliability, in term of internal consistency (through the Cronbach's alpha) and test-retest reliability (through the correlation coefficient), and the type of validation against external criteria (objective assessment of the sleep/wake cycle, body temperature, hormones and other questionnaires). Fifty studies that reported these data were included in the review: 7 studies used the MEQ-CA, 28 used the MESC and 15 used the CSM.ResultsThe percentage of studies reporting at least acceptable levels of internal consistency was high and similar between the three questionnaires. Evidence for test-retest reliability was scant, since only 3 studies were available; it was at least acceptable for the MESC (two studies with a time interval of 1 month), not acceptable for the MEQ-CA (one study with a time interval of 6 months), while no information was available for the CSM. As regards the validation evidence, the MEQ-CA has been validated by the highest number of external criteria (actigraphy, oral body temperature and other questionnaires), followed by the CSM (cortisol sampling and other questionnaires). The MESC has been validated only against self-report measures.ConclusionsThe present state of the art would suggest the use of the MEQ-CA to assess circadian preference in children and adolescents.
Who is in the transition gap? Transition from CAMHS to AMHS in the Republic of Ireland
Authors: McNicholas F. , Adamson M. , McNamara N. , Gavin B. , Paul M. , Ford T. , Barry S. , Dooley B. , Coyne I. , Cullen W. , Singh S. P. 
Published: February 2015

ObjectiveThe ITRACK study explored the process and predictors of transition between Child and Adolescent Mental Health Services (CAMHS) and Adult Mental Health Services (AMHS) in the Republic of Ireland.MethodFollowing ethical approval, clinicians in each of Ireland’s four Health Service Executive (HSE) areas were contacted, informed about the study and were invited to participate. Clinicians identified all cases who had reached the transition boundary (i.e. upper age limit for that CAMHS team) between January and December 2010. Data were collected on clinical and socio-demographic details and factors that informed the decision to refer or not refer to the AMHS, and case notes were scrutinised to ascertain the extent of information exchanged between services during transition.ResultsA total of 62 service users were identified as having crossed the transition boundary from nine CAMHS [HSE Dublin Mid-Leinster (n=40, 66%), HSE South (n=18, 30%), HSE West (n=2, 3%), HSE Dublin North (n=1, 2%)]. The most common diagnoses were attention deficit hyperactivity disorder (ADHD;n=19, 32%), mood disorders (n=16, 27%), psychosis (n=6, 10%) and eating disorders (n=5, 8%). Forty-seven (76%) of those identified were perceived by the CAMHS clinician to have an ‘on-going mental health service need’, and of these 15 (32%) were referred, 11 (23%) young people refused and 21 (45%) were not referred, with the majority (12, 57%) continuing with the CAMHS for more than a year beyond the transition boundary. Young people with psychosis were more likely to be referred [χ2(2, 46)=8.96,p=0.02], and those with ADHD were less likely to be referred [χ2(2, 45)=8.89,p=0.01]. Being prescribed medication was not associated with referral [χ2(2, 45)=4.515,p=0.11]. In referred cases (n=15), there was documented evidence of consent in two cases (13.3%), inferred in another four (26.7%) and documented preparation for transition in eight (53.3%). Excellent written communication (100%) was not supported by face-to-face planning meetings (n=2, 13.3%), joint appointments (n=1, 6.7%) or telephone conversations (n=1, 6.7%) between corresponding clinicians.ConclusionsDespite perceived on-going mental health (MH) service need, many young people are not being referred or are refusing referral to the AMHS, with those with ADHD being the most affected. CAMHS continue to offer on-going care past the transition boundary, which has resource implications. Further qualitative research is warranted to understand, in spite of perceived MH service need, the reason for non-referral by the CAMHS clinicians and refusal by the young person.
Space, time, and the development of shared leadership networks in multiteam systems
Authors: SULLIVAN SOPHIA D. , LUNGEANU ALINA , DECHURCH LESLIE A. , CONTRACTOR NOSHIR S. 
Published: February 2015

AbstractDigital technologies have created the potential for new forms of organizing among geographically dispersed individuals by connecting their ideas across the time and space in complex multiteam systems (MTSs). Realizing this potential requires novel forms of shared leadership structures to shepherd divergent and convergent thinking necessary to nurture innovation. While there is limited research on how space influences leadership and how the time influences leadership, there is virtually no theorizing on how space and time interact together to influence the emergence of shared leadership structures that facilitates innovation. A key contribution of this study is to utilize an agent-based model (ABM) that draws upon the research on leadership, networks, and innovation to specify generative mechanisms (or micro-processes) through which shared leadership structures emerge over space and time. The parameters in this model were estimated from empirical data. Results of virtual experiments (VE) yielded testable hypotheses suggesting that, over time, leadership capacity and between-team ties are negatively influenced by space. Furthermore, the computational model suggests that space increases the concentration of divergent leadership but decreases the concentration of convergent leadership. The study concludes by discussing the implications for the design of effective leadership structures to nurture innovation in MTSs.
Diet–animal fractionation of nitrogen stable isotopes reflects the efficiency of nitrogen assimilation in ruminants
Authors: Cantalapiedra-Hijar G. , Ortigues-Marty I. , Sepchat B. , Agabriel J. , Huneau J. F. , Fouillet H. 
Published: February 2015

The natural abundance of15N in animal proteins (δ15Nanimal) is greater than that in the diet consumed by the animals (δ15Ndiet), with a discrimination factor (Δ15N = δ15Nanimal− δ15Ndiet) that is known to vary according to nutritional conditions. The objectives of the present study were to test the hypothesis that Δ15N variations depend on the efficiency of nitrogen utilisation (ENU) in growing beef cattle, and to identify some of the physiological mechanisms responsible for this N isotopic fractionation in ruminants. Thus, we performed the regression of the Δ15N of plasma proteins obtained from thirty-five finishing beef cattle fed standard and non-conventional diets against different feed efficiency indices, including ENU. We also performed the regression of the Δ15N of different ruminant N pools (plasma and milk proteins, urine and faeces) against different splanchnic N fluxes obtained from multi-catheterised lactating dairy cows. The Δ15N of plasma proteins was negatively correlated with feed efficiency indices in beef cattle, especially ENU (body protein gain/N intake) and efficiency of metabolisable protein (MP) utilisation (body protein gain/MP intake). Although Δ15N obtained from different N pools in dairy cows were all negatively correlated with ENU, the highest correlation was found when Δ15N was calculated from plasma proteins. Δ15N showed no correlation with urea-N recycling or rumen NH3absorption, but exhibited a strong correlation with liver urea synthesis and splanchnic amino acid metabolism, which points to a dominant role of splanchnic tissues in the present N isotopic fractionation study.
What Do You Think of Philosophical Bioethics?
Authors: HÄYRY MATTI 
Published: February 2015

Abstract:This article provides an overview of approaches to bioethics—practical and theoretical, philosophical and nonphilosophical. It is argued that those who yearn for pragmatism and real-life relevance would do well to concentrate on politics, legislation, social policy, and lobbying. Those, on the other hand, who seek knowledge about our moral thought might be interested in philosophical bioethics—in the explication of concepts, arguments, views, and normative statements.
The Role of Philosophy in Global Bioethics
Authors: HELLSTEN SIRKKU K. 
Published: February 2015

Abstract:This article examines the relationship between philosophy and culture in global bioethics. First, it studies what is meant by the term “global” in global bioethics. Second, the author introduces four different types, or recognizable trends, in philosophical inquiry in bioethics today. The main argument is that, in order to make better sense of the complexity of the ethical questions and challenges we face today across the globe, we need to embrace the universal nature of self-critical and analytical philosophical analysis and argumentation, rather than using seemingly philosophical approaches to give unjustified normative emphasis on different cultural approaches to bioethics.
Your Morality, My Mortality
Authors: RICH BEN A. 
Published: February 2015

Abstract:Recently the scope of protections afforded those healthcare professionals and institutions that refuse to provide certain interventions on the grounds of conscience have expanded, in some instances insulating providers (institutional and individual) from any liability or sanction for harms that patients experience as a result. With the exponential increase in the penetration of Catholic-affiliated healthcare across the country, physicians and nurses who are not practicing Catholics are nevertheless required to execute documents pledging to conform their patient care to the Ethical and Religious Directives for Health Care Services as a condition of employment or medical staff privileges. In some instances, doing so may result in patient morbidity or mortality or violate professional standards for respecting advance directives or surrogate decisionmaking. This article challenges the ethical propriety of such institutional mandates and argues that legal protections for conscientious refusal must provide redress for patients who are harmed by care that falls below the prevailing clinical standards.
Sub-100 nm resolution microscopy based on proximity projection grating scheme
Authors: Hu Feng , Somekh Michael G. , Albutt Darren J. , Webb Kevin , Moradi Emilia , See Chung W. 
Published: February 2015

AbstractStructured illumination microscopy (SIM) has been widely used in life science imaging applications. The maximum resolution improvement of SIM, compared to conventional bright field system is a factor of 2. Here we present an approach to structured illumination microscopy using the proximity projection grating scheme (PPGS), which has the ability to further enhance the SIM resolution without invoking any nonlinearity response from the sample. With the PPGS-based SIM, sub-100 nm resolution has been obtained experimentally and results corresponding to 2.4 times resolution improvement are presented. Furthermore, it will be shown that an improvement of greater than 3 times can be achieved.
Luminescence in the fluoride-containing phosphate-based glasses: A possible origin of their high resistance to nanosecond pulse laser-induced damage
Authors: Wang Pengfei , Lu Min , Gao Fei , Guo Haitao , Xu Yantao , Hou Chaoqi , Zhou Zhiwei , Peng Bo 
Published: February 2015

AbstractFusion power offers the prospect of an almost inexhaustible source of energy for future generations. It was reported that fusion fuel gains exceeding unity on the National Ignition Facility (NIF) were achieved, but so far great deal of scientific and engineering challenges have to be overcome for realizing fusion power generation. There is a bottleneck for color-separation gratings in NIF and other similar inertial confinement fusion (ICF) lasers. Here we show a series of high performance phosphate-based glasses that can transmit the third harmonic frequency (3ω) laser light with high efficiency meanwhile filter the fundamental (1ω) and the second harmonic frequency (2ω) laser lights through direct absorption and especially they exhibit excellent damage threshold induced by nanosecond pulse laser compared with that of the fused silica used in NIF. Yellowish-orange fluorescence emits during the laser-material interaction process and it can be tailored through regulating the glass structure. Study on its structural origin suggests that the fluorescence emission is a key factor that conduces to the high laser-induced damage resistance of these glasses. The results also indicated the feasibility of utilizing these high performance glasses in novel color separation optics, allowing novel design for the final optics assembly in ICF lasers.
Rate-dependent phase transitions in Li2FeSiO4 cathode nanocrystals
Authors: Lu Xia , Wei Huijing , Chiu Hsien-Chieh , Gauvin Raynald , Hovington Pierre , Guerfi Abdelbast , Zaghib Karim , Demopoulos George P. 
Published: February 2015

AbstractNanostructured lithium metal orthosilicate materials hold a lot of promise as next generation cathodes but their full potential realization is hampered by complex crystal and electrochemical behavior. In this work Li2FeSiO4 crystals are synthesized using organic-assisted precipitation method. By varying the annealing temperature different structures are obtained, namely the monoclinic phase at 400°C, the orthorhombic phase at 900°C and a mixed phase at 700°C. The three Li2FeSiO4 crystal phases exhibit totally different charge/discharge profiles upon delithiation/lithiation. Thus the 400°C monoclinic nanocrystals exhibit initially one Li extraction via typical solid solution reaction, while the 900°C orthorhombic crystals are characterized by unacceptably high cell polarization. In the meantime the mixed phase Li2FeSiO4 crystals reveal a mixed cycling profile. We have found that the monoclinic nanocrystals undergo phase transition to orthorhombic structure resulting in significant progressive deterioration of the material's Li storage capability. By contrast, we discovered when the monoclinic nanocrystals are cycled initially at higher rate (C/20) and subsequently subjected to low rate (C/50) cycling the material's intercalation performance is stabilized. The discovered rate-dependent electrochemically-induced phase transition and stabilization of lithium metal silicate structure provides a novel and potentially rewarding avenue towards the development of high capacity Li-ion cathodes.
Widespread presence of the pathogenic fungus Batrachochytrium dendrobatidis in wild amphibian communities in Madagascar
Authors: Bletz Molly C. , Rosa Gonçalo M. , Andreone Franco , Courtois Elodie A. , Schmeller Dirk S. , Rabibisoa Nirhy H. C. , Rabemananjara Falitiana C. E. , Raharivololoniaina Liliane , Vences Miguel , Weldon Ché , Edmonds Devin , Raxworthy Christopher J. , Harris Reid N. , Fisher Matthew C. , Crottini Angelica 
Published: February 2015

AbstractAmphibian chytridiomycosis, an emerging infectious disease caused by the fungus Batrachochytrium dendrobatidis (Bd), has been a significant driver of amphibian declines. While globally widespread, Bd had not yet been reported from within Madagascar. We document surveys conducted across the country between 2005 and 2014, showing Bd's first record in 2010. Subsequently, Bd was detected in multiple areas, with prevalence reaching up to 100%. Detection of Bd appears to be associated with mid to high elevation sites and to have a seasonal pattern, with greater detectability during the dry season. Lineage-based PCR was performed on a subset of samples. While some did not amplify with any lineage probe, when a positive signal was observed, samples were most similar to the Global Panzootic Lineage (BdGPL). These results may suggest that Bd arrived recently, but do not exclude the existence of a previously undetected endemic Bd genotype. Representatives of all native anuran families have tested Bd-positive and exposure trials confirm infection by Bd is possible. Bd's presence could pose significant threats to Madagascar's unique “megadiverse” amphibians.
Flow enhancement of water-based nanoparticle dispersion through microscale sedimentary rocks
Authors: Yu Haiyang , He Youwei , Li Peng , Li Shuang , Zhang Tiantian , Rodriguez-Pin Elena , Du Song , Wang Chenglong , Cheng Shiqing , Bielawski Christopher W. , Bryant Steven L. , Huh Chun 
Published: March 2015

AbstractUnderstanding and controlling fluids flow at the microscale is a matter of growing scientific and technological interest. Flow enhancements of water-based nanoparticle dispersions through microscale porous media are investigated through twelve hydrophilic sedimentary rocks with pore-throat radius between 1.2 and 10 μm, which are quantitatively explained with a simple model with slip length correction for Darcy flow. Both as wetting phase, water exhibited no-slip Darcy flow in all cores; however, flow enhancement of nanoparticle dispersions can be up to 5.7 times larger than that of water and it increases with the decreasing of pore-throat radius. The experimental data reveals characteristic slip lengths are of order 500 and 1000 nm for 3M® and HNPs-1 nanoparticles, respectively, independent of the lithology or nanoparticle concentration or shear rate. Meanwhile, the phenomenon of flow degradation is observed for HNPs-2 nanoparticles. These results explore the feasible application of using nanoparticle dispersions to control flow at the microscale.
Does Balloon Kyphoplasty Deliver More Cement Safely into Osteoporotic Vertebrae with Compression Fractures Compared with Vertebroplasty? A Study in Vertebral Analogues
Authors: Abduljabbar Fahad H. , Al-jurayyan Abdulaziz , Alqahtani Saad , Sardar Zeeshan M. , Saluja Rajeet Singh , Ouellet Jean , Weber Michael , Steffen Thomas , Beckman Lorne , Jarzem Peter 
Published: February 2015

Study Design A biomechanical and radiographic study using vertebral analogues. Objectives Kyphoplasty and vertebroplasty are widely used techniques to alleviate pain in fractures secondary to osteoporosis. However, cement leakage toward vital structures like the spinal cord can be a major source of morbidity and even mortality. We define safe cement injection as the volume of the cement injected into a vertebra before the cement leakage occurs. Our objective is to compare the amount of cement that can be safely injected into an osteoporotic vertebra with simulated compression fracture using either vertebroplasty or balloon kyphoplasty techniques. Methods Forty artificial vertebral analogues made of polyurethane with osteoporotic cancellous matrix representing the L3 vertebrae were used for this study and were divided into four groups of 10 vertebrae each. The four groups tested were: low-viscosity cement injected using vertebroplasty, high-viscosity cement injected using vertebroplasty, low-viscosity cement injected using balloon kyphoplasty, and high-viscosity cement injected using balloon kyphoplasty. The procedures were performed under fluoroscopic guidance. The injection was stopped when the cement started protruding from the created vascular channel in the osteoporotic vertebral fracture model. The main outcome measured was the volume of the cement injected safely into a vertebra before leakage through the posterior vascular channel. Results The highest volume of the cement injected was in the vertebroplasty group using high-viscosity cement, which was almost twice the injected volume in the other three groups. One-way analysis of variance comparing the four groups showed a statistically significant difference ( p < 0.005). Conclusions High-viscosity cement injected using vertebroplasty delivers more cement volume before cement leakage and fills the vertebral body more uniformly when compared with balloon kyphoplasty in osteoporotic vertebrae with compression fractures.
Radiation-Induced Intraspinal Chondrosarcoma: A Case Report
Authors: Obid Peter , Vierbuchen Mathias , Wolf Eduard , Reichl Michael , Niemeyer Thomas , Übeyli Hüseyin , Richter Alexander 
Published: February 2015

Study Design Case report and review of the literature. Objective To report a unique case of an intraspinal chondrosarcoma that was diagnosed 18 years after radiotherapy for a cervical carcinoma and its remarkably unusual clinical presentation. Methods A retrospective case description of an intraspinal mass lesion that occurred 6 weeks after previous spinal surgery. Results Within ∼9 weeks, the tumor had infiltrated the peritoneal cavity and reached the lumbar subcutaneous tissue. Conclusion Radiation-induced sarcomas are rare, are highly aggressive, and may be difficult to diagnose. Furthermore, the only means of achieving long-term survival is through early and extensive surgery.