bluuebunny/crossref_metadata_2025_split huggingface dataset:
Unsold Versus Unbought Commitment: Minimum Total Commitment Contracts with Nonzero Setup Costs
Authors: Yuan Quan , Chua Geoffrey A. , Liu Xing , Chen Youhua (Frank) 
Published: February 2015

We study a minimum total commitment (MTC) contract embedded in a finite‐horizon periodic‐review inventory system. Under this contract, the buyer commits to purchase a minimum quantity of a single product from the supplier over the entire planning horizon. We consider nonstationary demand and per‐unit cost, discount factor, and nonzero setup cost. Because the formulations used in existing literature are unable to handle our setting, we develop a new formulation based on a state transformation technique using unsold commitment instead of unbought commitment as state variable. We first revisit the zero setup cost case and show that the optimal ordering policy is an unsold‐commitment‐dependent base‐stock policy. We also provide a simpler proof of the optimality of the dual base‐stock policy. We then study the nonzero setup cost case and prove a new result, that the optimal solution is an unsold‐commitment‐dependent ( s, S) policy. We further propose two heuristic policies, which numerical tests show to perform very well. We also discuss two extensions to show the generality of our method's effectiveness. Finally, we use our results to examine the effect of different contract terms such as duration, lead time, and commitment on buyer's cost. We also compare total supply chain profits under periodic commitment, MTC, and no commitment.
Characterization of the watermelon seedling infection process by Fusarium oxysporum f. sp. niveum
Authors: Zhang M. , Xu J. H. , Liu G. , Yao X. F. , Li P. F. , Yang X. P. 
Published: February 2015

Fusarium oxysporum f. sp. niveum (FON) is the causal pathogen of fusarium wilt in watermelon. Understanding the interactions of watermelon seedlings and FON is of scientific and practical importance for disease control. The colonization dynamics of a susceptible watermelon cultivar, Sumi 1 (SM 1), were visualized using a green fluorescent protein (GFP)‐expressing strain of FON race 1 (FON 1‐GFP). Within 2 days post‐inoculation (dpi), hyphae adhered to and grew on epidermal cells. At 3 dpi, hyphae crossed the epidermis, penetrated into the cortex and progressed through parenchymal cell borders reaching the xylem vessels at 7 dpi. Growth of hyphae was restricted to the xylem vessels even in the colonized lower hypocotyl. The responses of SM 1 seedlings to infection were analysed. In the roots of SM 1, infected xylem vessels were plugged with gums and tyloses and some occluded vessels were shed from the root vascular tissue. Parenchyma cells surrounding the vascular cylinder showed wall thickening and cell disintegration, which eventually formed cavities. Hypocotyls of most SM 1 plants were also infected. Vascular tissues were densely colonized by hyphae until the vascular bundle became hollow and plants withered. Moreover, the expression patterns of six defence‐related genes in roots of SM 1 were analysed using real‐time quantitative PCR. Transcript levels of plant defensin‐like genes ClPDF2.1 and ClPDF2.4, phenylalanine ammonia lyase (PAL), chitinase (CHI) and ascorbate peroxidase (APX) were significantly induced in SM 1 roots during FON 1 infection, while polyphenoloxidase (PPO) did not show significant responses to FON 1 infection.
Comparative Expression Analysis of Gametogenesis‐Associated Genes in Foetal and Adult Bubaline (Bubalus bubalis) Ovaries and Testes
Authors: Shah SM , Saini N , Ashraf S , Zandi M , Singh MK , Manik RS , Singla SK , Palta P , Chauhan MS 
Published: February 2015

ContentsThis study was conducted to identify and analyse the expression of gametogenesis‐associated genes and proteins in foetal and adult buffalo gonads of both the sexes. Relative quantification of the genes was determined by qPCR and Western blotting. Immunohistochemistry was also performed for various gametogenesis‐associated proteins in foetal and adult gonads of both the sexes. We observed significantly (p < 0.05) increased expression of primordial germ cell‐specific, meiotic as well as genes associated with oocyte maturation and development in foetal ovaries as compared to the adult ones. However, significantly (p < 0.05) increased expression of proteins associated with oocyte maturation like GDF9 and ZP4 was found in adult ovaries, indicating temporal regulation of mRNA translation during oogenesis. Meiotic genes showed significantly (p < 0.05) increased expression in adult testes as compared to foetal testes and ovaries, indicating onset of meiosis at a later stage in spermatogenesis. In general, the expression of primordial germ cell‐associated as well as meiotic genes was higher in adult testes, indicating the increased biological activity in the organ. Immunohistochemistry revealed localized expression of gametogenesis‐associated proteins in ovarian follicles and seminiferous tubules of testes, while the surrounding somatic tissues were devoid of these proteins. The study gives an understanding of the sequential and temporal events of gene expression as well as mRNA translation during male and female gametogenesis. It could also be concluded that follicles and seminiferous tubules are the functional units of the female and male gonads, respectively, and their function could be enhanced by appropriate chemical and genetic intervention of the somatic tissue immediately surrounding them. This assumes importance in the context that buffalo attains sexual maturity at an older age of 2–3 years and have smaller ovaries with lesser number of primordial follicles in comparison with cattle, which is suggested to be the main reason of their poor breeding performance.
Stem Cells from Foetal Adnexa and Fluid in Domestic Animals: An Update on Their Features and Clinical Application
Authors: Iacono E , Rossi B , Merlo B 
Published: February 2015

ContentsOver the past decade, stem cell research has emerged as an area of major interest for its potential in regenerative medicine applications. This is in constant need of new cell sources to conceive regenerative medicine approaches for diseases that are still without therapy. Scientists drew the attention towards alternative sources such as foetal adnexa and fluid, as these sources possess many advantages: first of all, cells can be extracted from discarded foetal material and it is non‐invasive and inexpensive for the patient; secondly, abundant stem cells can be obtained; and finally, these stem cell sources are free from ethical considerations. Cells derived from foetal adnexa and fluid preserve some of the characteristics of the primitive embryonic layers from which they originate. Many studies have demonstrated the differentiation potentialin vitroandin vivotowards mesenchymal and non‐mesenchymal cell types; in addition, the immune‐modulatory properties make these cells a good candidate for allo‐ and xenotransplantation. Naturally occurring diseases in domestic animals can be more ideal as disease model of human genetic and acquired diseases and could help to define the potential therapeutic use efficiency and safety of stem cells therapies. This review offers an update on the state of the art of characterization of domestic animals'MSCs derived from foetal adnexa and fluid and on the latest findings in pre‐clinical or clinical setting of the stem cell populations isolated from these sources.
Effects of Ovariohysterectomy on Oxidative Stress Markers in Female Dogs
Authors: Szczubial M , Kankofer M , Bochniarz M , Dąbrowski R 
Published: February 2015

ContentsNumerous studies reported an increase of oxidative stress increases in both women and female laboratory animals after ovariectomy. However, there is little information about the evaluation of antioxidative/oxidative status in ovariectomized dogs. The purpose of this study was to examine the changes in oxidative stress markers after ovariohysterectomy (OHE) in female dogs. The study included eighteen healthy mongrel female dogs. Blood samples were collected immediately before surgery and 14 and 30 days after surgery. Following parameters of oxidative stress intensity were determined: the erythrocyte activity of glutathione peroxidase (GSH‐Px) and superoxide dismutase (SOD) as well as the plasma concentrations of thiobarbituric acid reactive substances (TBARS), radical cations of N,N, diethylpara‐phenylene diamine (RC‐DEPPD), sulfhydryl groups (SHgroups), bityrosine and formylkynurenine. The activity ofGSH‐Px increased markedly, although not significantly, 14 days afterOHEand then significantly decreased at 30 days afterOHE. A significant increase in plasmaTBARS, bityrosine and formylkynurenine concentrations and a decrease inSHgroup content were concurrently noted at 30 days after surgery. Acquired results suggested that a loss of control overROSproduction occurred in female dogs afterOHE, which could lead to oxidative stress in the late post‐operative period. In conclusion, our findings indicated thatOHEis related with the risk of oxidative stress in the late period after operations. Given that oxidative stress contributes to the pathogenesis of various diseases, this may suggest an increased risk of disorders in ovariectomized female dogs; however, further studies are necessary to confirm this hypothesis.
Chlamydia abortus in Cows Oviducts, Occasional Event or Causal Connection?
Authors: Appino S , Vincenti L , Rota A , Pellegrini S , Chieppa MN , Cadoni V , Pregel P 
Published: February 2015

ContentsFifty‐seven genital tracts of regularly slaughtered culled Piedmontese cows, aged 7.4 ± 4.3 years (mean ± SD), range: 2.6–15.6 years, were grossly and microscopically examined. DNA extracted from oviducts was subjected to PCR to evaluate the presence of Chlamydia spp. The 15 PCR‐positive oviducts were subjected to Sanger sequencing and showed the presence of Chamydia abortus, with an identity range between 99 and 100%. Nine of the PCR‐positive samples belonged to the 24 animals with a normal macroscopic appearance of the whole genital tract (percentage of positive oviducts in normal genital tracts 9/24 = 37.5%), while six belonged to the 33 genital tracts with lesions in one or more organs (percentage of positive oviducts in pathological genital tracts 6/33 = 18.1%); of these, a single animal had salpingitis. The detection of C. abortus in bovine oviducts is of particular interest because it has never been previously investigated or reported.
The Concentrations of Inflammatory Cytokines and Acute‐Phase Proteins in the Peripheral Blood and Uterine Washings in Cows with Pyometra
Authors: Brodzki P , Kostro K , Brodzki A , Ziętek J 
Published: February 2015

ContentsThe development of pyometra in cows depends largely on the state of local immunity of the uterus. The objective of the study was to evaluate the concentration of the following proinflammatory cytokines: tumour necrosis factor (TNF‐α) and interleukin‐6 (IL‐6); anti‐inflammatory cytokine: interleukin‐10 (IL‐10); and acute‐phase proteins (APPs): haptoglobin (Hp) and serum amyloid A (SAA), in serum and uterine washings in cows with pyometra and healthy animals. The study was performed on 20 cows divided into two groups based on the results of cytological and ultrasonographic tests: a pyometra and a healthy group (10 cows per group). Experimental material consisted of blood serum and uterine washings. The levels of the following cytokines, TNF‐α, IL‐6, IL‐10 and APPs – Hp and SAA, in the study material were determined by ELISA. The results showed that the values of TNF‐α, IL‐6, IL‐10 as well as SAA and Hp were significantly higher in serum of cows with pyometra compared to controls (p < 0.001). The uterine washings had significantly higher levels of IL‐6, IL‐10, and Hp in pyometra cows compared to the control (p < 0.001). Our results indicate that it is possible to monitor the course of pyometra in cows based on the evaluation of the concentration of cytokines and Hp in the serum and uterine washings. Simultaneous evaluation of selected indicators of antagonistic interaction can be helpful in determining the current status of local immunity of the uterus. On this basis, it could be possible to properly select an adjunctive therapy in the form of immunomodulating preparations.
Risk of infection and disease with Mycobacterium tuberculosis among children identified through prospective community‐based contact screening in Indonesia
Authors: Triasih Rina , Robertson Colin , Duke Trevor , Graham Stephen M. 
Published: February 2015

AbstractObjectiveTo identify characteristics of the child contact, index case or environment that are associated with infection or tuberculosis in child contacts in an urban community in Indonesia.MethodChildren who were close contacts of an index case with pulmonary tuberculosis were screened for infection and disease in Yogyakarta, Indonesia from August 2010 to December 2012. Data of the index case and child were collected prospectively, and all child contacts had clinical assessment, tuberculin skin test (TST) and chest X‐ray performed. Those with clinically suspected tuberculosis also had sputum examined by Xpert MTB/RIF and culture. Child contacts were managed according to national guidelines, followed for 12 months and had a final classification of either tuberculosis ‘disease’, latent tuberculous infection (LTBI) or ‘exposed only’.ResultsAbout 269 children of 141 index cases were investigated. Final classification was tuberculosis in 25 (9%) and LTBI in 121 (45%). The risk of infection was significantly greater if the source case was female (AOR 1.7; 95% CI: 1.0–2.8), had sputum smear‐positive tuberculosis (AOR 3.0; 95% CI 1.5–6.0) or slept in the same room (AOR 1.7, 95% CI 1.0–2.9). A positive TST was independently associated with a diagnosis of tuberculosis (AOR 7.3; 95% CI 2.4–22).ConclusionThis study highlights the high risk and the risk factors associated with tuberculosis and LTBI among child contacts in Indonesia.
Polymethylmethacrylate orbital implants with interconnecting channels. A retrospective study following enucleation in dogs and cats
Authors: Oriá Arianne P. , de Souza Mary'Anne Rodrigues , Dórea Neto Francisco de Assis , Gomes Junior Deusdete C. , Estrela‐Lima Alessandra , Muramoto Caterina , Costa Neto João Moreira , Ofri Ron 
Published: February 2015

AbstractPurposeThis study describes the use of polymethylmethacrylate implants with interconnecting channels (PIIC) to fill the orbit following enucleation in 31 dogs and 11 cats.MethodSeven channels were drilled into the implant. A central channel, running from thePIICpole to its flat surface, was used to pass sutures anchoring thePIICto the orbital fascia, minimizing the likelihood of extrusion. Six more channels allowed ingrowth of fibrovascular tissue into thePIIC, which reduces the risk of extrusion. Patients were evaluated 3, 10, and 30 days postoperatively, with 15 of 42 patients followed for 6–20 months. Ultrasound examination was performed in seven patients 15–510 days postoperatively, and two implants were studied histopathologically.ResultsImplants were well tolerated and prevented skin concavity, leading to good cosmetic results. Blood flow was imaged in vessels growing into the channels, and histopathologically a collagenous, fibrovascular capsule was seen surrounding thePIICand invading its channels.ConclusionsPIICs are a safe and cosmetic solution to anophthalmic orbits, allowing ingrowth of blood vessels and fibrovascular tissue.
Draft Genome Sequence of Tolypothrix boutellei Strain VB521301
Authors: Chandrababunaidu Mathu Malar , Singh Deeksha , Sen Diya , Bhan Sushma , Das Subhadeep , Gupta Akash , Adhikary Siba Prasad , Tripathy Sucheta 
Published: February 2015

ABSTRACT
We report here the draft genome sequence of the filamentous nitrogen-fixing cyanobacterium Tolypothrix boutellei strain VB521301. The organism is lipid rich and hydrophobic and produces polyunsaturated fatty acids which can be harnessed for industrial purpose. The draft genome sequence assembled into 11,572,263 bp with 70 scaffolds and 7,777 protein coding genes.
Identification and Whole-Genome Sequence Analysis of Tembusu Virus GX2013G, Isolated from a Cherry Valley Duckling in Southern China
Authors: Zeng Tingting , Xie Zhixun , Xie Liji , Deng Xianwen , Xie Zhiqin , Huang Li , Luo Sisi , Huang Jiaoling 
Published: February 2015

ABSTRACT
A duck tembusu virus (DTMUV) was isolated from the brain of a Cherry Valley duckling that showed neurological signs by using a specific-pathogen-free chicken embryo. The isolate was named GX2013G (GenBank accession no. KM275941). The strain GX2013G was identified with reverse transcription-PCR (RT-PCR), and the amplicon was sequenced. The genome that was obtained is 10,990 nucleotides in length and contains a single open reading frame encoding a putative polyprotein of 3,425 amino acids. This study will advance the understanding of the epidemiology and molecular characteristics of tembusu virus (TMUV) in Guangxi and further studies of the mechanisms of virus replication and pathogenesis.
Draft Genome Sequence of Stenotrophomonas maltophilia Strain B418, a Promising Agent for Biocontrol of Plant Pathogens and Root-Knot Nematode
Authors: Wu Yuanzheng , Wang Yilian , Li Jishun , Hu Jindong , Chen Kai , Wei Yanli , Bazhanov Dmitry P. , Bazhanova Alesia A. , Yang Hetong 
Published: February 2015

ABSTRACT

Stenotrophomonas maltophilia
strain B418 was isolated from a barley rhizosphere in China. This bacterium exhibits broad-spectrum inhibitory activities against plant pathogens and root-knot nematode along with growth-promoting effects. Here, we present the draft genome sequence of
S. maltophilia
B418.
Draft Genome Sequence of Strain R13-38 from a Francisella tularensis Outbreak in Sweden
Authors: Alm Erik , Advani Abdolreza , Bråve Andreas , Wahab Tara 
Published: February 2015

ABSTRACT

We have whole-genome sequenced a
Francisella tularensis
subsp.
holarctica
(also known as type B) strain from an outbreak in Sweden in 2013, derived from a privately owned well for drinking water.
Metagenomic Evaluation of Bacterial and Archaeal Diversity in the Geothermal Hot Springs of Manikaran, India
Authors: Bhatia Sonu , Batra Navneet , Pathak Ashish , Green Stefan J. , Joshi Amit , Chauhan Ashvini 
Published: February 2015

ABSTRACT

Bacterial and archaeal diversity in geothermal spring water were investigated using 16S rRNA gene amplicon metagenomic sequencing. This revealed the dominance of
Firmicutes
,
Aquificae
, and the Deinococcus-Thermus group in this thermophilic environment. A number of sequences remained taxonomically unresolved, indicating the presence of potentially novel microbes in this unique habitat.
Genome Sequence of Bradyrhizobium japonicum E109, One of the Most Agronomically Used Nitrogen-Fixing Rhizobacteria in Argentina
Authors: Torres Daniela , Revale Santiago , Obando Melissa , Maroniche Guillermo , Paris Gastón , Perticari Alejandro , Vazquez Martín , Wisniewski-Dyé Florence , Martínez-Abarca Francisco , Cassán Fabricio 
Published: February 2015

ABSTRACT

We present here the complete genome sequence of
Bradyrhizobium japonicum
strain E109, one of the most used rhizobacteria for soybean inoculation in Argentina since the 1970s. The genome consists of a 9.22-Mbp single chromosome and contains several genes related to nitrogen fixation, phytohormone biosynthesis, and a rhizospheric lifestyle.
Genome Sequence and Annotation of a Human Infection Isolate of Escherichia coli O26:H11 Involved in a Raw Milk Cheese Outbreak
Authors: Galia Wessam , Mariani-Kurkdjian Patricia , Loukiadis Estelle , Blanquet-Diot Stéphanie , Leriche Françoise , Brugère Hubert , Shima Ayaka , Oswald Eric , Cournoyer Benoit , Thevenot-Sergentet Delphine 
Published: February 2015

ABSTRACT

The consumption of raw milk cheese can expose populations to Shiga toxin-producing
Escherichia coli
(STEC). We report here the genome sequence of an
E. coli
O26:H11 strain isolated from humans during the first raw milk cheese outbreak described in France (2005).
Draft Genome Sequence of Xanthomonas arboricola Strain 3004, a Causal Agent of Bacterial Disease on Barley
Authors: Ignatov Alexander N. , Kyrova Elena I. , Vinogradova Svetlana V. , Kamionskaya Anastasia M. , Schaad Norman W. , Luster Douglas G. 
Published: February 2015

ABSTRACT

We report here the annotated genome sequence of
Xanthomonas arboricola
strain 3004, isolated from barley leaves with symptoms of streak and capable of infecting other plant species. We sequenced the genome of
X. arboricola
strain 3004 to improve the understanding of molecular mechanisms of the pathogenesis and evolution of the genus
Xanthomonas
.
Draft Genome Sequence of a Cellulase-Producing Psychrotrophic Paenibacillus Strain, IHB B 3415, Isolated from the Cold Environment of the Western Himalayas, India
Authors: Dhar Hena , Swarnkar Mohit Kumar , Gulati Arvind , Singh Anil Kumar , Kasana Ramesh Chand 
Published: February 2015

ABSTRACT
Paenibacillus sp. strain IHB B 3415 is a cellulase-producing psychrotrophic bacterium isolated from a soil sample from the cold deserts of Himachal Pradesh, India. Here, we report an 8.44-Mb assembly of its genome sequence with a G+C content of 50.77%. The data presented here will provide insights into the mechanisms of cellulose degradation at low temperature.
Draft Genome of Pseudomonas sp. Strain 11/12A, Isolated from Lake Washington Sediment
Authors: McTaggart Tami L. , Shapiro Nicole , Woyke Tanja , Chistoserdova Ludmila 
Published: February 2015

ABSTRACT
We announce here the genome sequencing of Pseudomonas sp. strain 11/12A from Lake Washington sediment. From the genome content, a versatile lifestyle is predicted but not one of bona fide methylotrophy. With the availability of its genomic sequence, Pseudomonas sp. 11/12A presents a prospective model for studying microbial communities in lake sediments.
Draft Genome Sequence of an Extensively Drug-Resistant Mycobacterium tuberculosis Manu-Ancestor Spoligo-International Type 523 Isolate from Thailand
Authors: Regmi Sanjib M. , Chaiprasert Angkana , Coker Olabisi O. , Disratthakit Areeya , Prammananan Therdsak , Suriyaphol Prapat , Yik-Ying Teo , Twee Hee Ong 
Published: February 2015

ABSTRACT

We present the draft genome sequence of DS-16780, with a rare spoligo-international type (SIT) 523 (777777777777771) genotype, which reveals an extensively drug-resistant
Mycobacterium tuberculosis
(XDR-TB) phenotype. The isolate is a representative of clonal XDR-TB from the western part of Thailand.
Draft Genome Sequence of Pseudoalteromonas luteoviolacea HI1, Determined Using Roche 454 and PacBio Single-Molecule Real-Time Hybrid Sequencing
Authors: Asahina Audrey Y. , Hadfield Michael G. 
Published: February 2015

ABSTRACT

We report here the 6.0-Mb draft genome assembly of
Pseudoalteromonas luteoviolacea
strain HI1 using Roche 454 and PacBio single-molecule real-time hybrid-sequencing analysis. This strain is of biological importance since it has the capacity to induce the settlement and metamorphosis of the serpulid polychaete Hydroides elegans and the coral
Pocillopora damicornis
.
Draft Genome Sequence of Hafnia paralvei Strain GTA-HAF03
Authors: Kohlman Melissa E. , Carrillo Catherine D. , Wong Alex 
Published: February 2015

ABSTRACT

Hafnia paralvei
is a Gram-negative member of the
Enterobacteriaceae
family, closely related to the opportunistic pathogen
Hafnia alvei
. We report here the first draft genome sequence of H. paralvei, from the beef trim isolate GTA-HAF03, consisting of a 5.0-Mbp assembly encoding 4,382 proteins and 90 predicted RNAs.
Complete Genome Sequence of Riemerella anatipestifer Serotype 1 Strain CH3
Authors: Wang Xiaolan , Ding Chan , Han Xiangan , Wang Shaohui , Yue Jiaping , Hou Wanwan , Cao Shoulin , Zou Jiechi , Yu Shengqing 
Published: February 2015

ABSTRACT

Riemerella anatipestifer
is a well-described pathogenic bacterium, which is reported worldwide as the cause of epizootic infectious polyserositis of waterfowl and other avian species. Here, we present the complete genome sequence of
R. anatipestifer
strain CH3, the serotype 1 prevalent in China.