bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gallium Oxide Nanorods: Novel, Template‐Free Synthesis and High Catalytic Activity in Epoxidation Reactions
Authors: Lueangchaichaweng Warunee , Brooks Neil R. , Fiorilli Sonia , Gobechiya Elena , Lin Kaifeng , Li Li , Parres‐Esclapez Sonia , Javon Elsa , Bals Sara , Van Tendeloo Gustaaf , Martens Johan A. , Kirschhock Christine E. A. , Jacobs Pierre A. , Pescarmona Paolo P. 
Published: January 2014

AbstractGallium oxide nanorods with unprecedented small dimensions (20–80 nm length and 3–5 nm width) were prepared using a novel, template‐free synthesis method. This nanomaterial is an excellent heterogeneous catalyst for the sustainable epoxidation of alkenes with H2O2, rivaling the industrial benchmark microporous titanosilicate TS‐1 with linear alkenes and being much superior with bulkier substrates. A thorough characterization study elucidated the correlation between the physicochemical properties of the gallium oxide nanorods and their catalytic performance, and underlined the importance of the nanorod morphology for generating a material with high specific surface area and a high number of accessible acid sites.
Highly Efficient Near‐Infrared Organic Light‐Emitting Diode Based on a Butterfly‐Shaped Donor–Acceptor Chromophore with Strong Solid‐State Fluorescence and a Large Proportion of Radiative Excitons
Authors: Yao Liang , Zhang Shitong , Wang Rong , Li Weijun , Shen Fangzhong , Yang Bing , Ma Yuguang 
Published: January 2014

AbstractThe development of near‐infrared (NIR) organic light‐emitting diodes (OLEDs) is of growing interest. Donor–acceptor (D–A) chromophores have served as an important class of NIR materials for NIR OLED applications. However, the external quantum efficiencies (EQEs) of NIR OLEDs based on conventional D–A chromophores are typically below 1 %. Reported herein is a butterfly‐shaped D–A compound, PTZ‐BZP. A PTZ‐BZP film displayed strong NIR fluorescence with an emission peak at 700 nm, and the corresponding quantum efficiency reached 16 %. Remarkably, the EQE of the NIR OLED based on PTZ‐BZP was 1.54 %, and a low efficiency roll‐off was observed, as well as a high radiative exciton ratio of 48 %, which breaks through the limit of 25 % in conventional fluorescent OLEDs. Experimental and theoretical investigations were carried out to understand the excited‐state properties of PTZ‐BZP.
Near‐Infrared‐Light‐Mediated Imaging of Latent Fingerprints based on Molecular Recognition
Authors: Wang Jie , Wei Ting , Li Xinyang , Zhang Binhao , Wang Jiaxi , Huang Chi , Yuan Quan 
Published: January 2014

AbstractPhotoluminescence is one of the most sensitive techniques for fingerprint detection, but it also suffers from background fluorescence and selectivity at the expense of generality. The method described herein integrates the advantages of near‐infrared‐light‐mediated imaging and molecular recognition. In principle, upconversion nanoparticles (UCNPs) functionalized with a lysozyme‐binding aptamer were used to detect fingerprints through recognizing lysozyme in the fingerprint ridges. UCNPs possess the ability to suppress background fluorescence and make it possible for fingerprint imaging on problematic surfaces. Lysozyme, a universal compound in fingerprints, was chosen as the target, thus simultaneously meeting the selectivity and generality criteria in photoluminescence approaches. Fingerprints on different surfaces and from different people were detected successfully. This strategy was used to detect fingerprints with cocaine powder by using UCNPs functionalized with a cocaine‐binding aptamer.
A Double‐Imprinted Diffraction‐Grating Sensor Based on a Virus‐Responsive Super‐Aptamer Hydrogel Derived from an Impure Extract
Authors: Bai Wei , Spivak David A. 
Published: January 2014

AbstractThe detection of viruses is of interest for a number of fields including biomedicine, environmental science, and biosecurity. Of particular interest are methods that do not require expensive equipment or trained personnel, especially if the results can be read by the naked eye. A new “double imprinting” method was developed whereby a virus‐bioimprinted hydrogel is further micromolded into a diffraction grating sensor by using imprint‐lithography techniques to give a “Molecularly Imprinted Polymer Gel Laser Diffraction Sensor” (MIP‐GLaDiS). A simple laser transmission apparatus was used to measure diffraction, and the system can read by the naked eye to detect the Apple Stem Pitting Virus (ASPV) at concentrations as low as 10 ng mL−1, thus setting the limit of detection of these hydrogels as low as other antigen‐binding methods such as ELISA or fluorescence‐tag systems.
Building Nanocomposite Magnets by Coating a Hard Magnetic Core with a Soft Magnetic Shell
Authors: Liu Fei , Zhu Jinghan , Yang Wenlong , Dong Yunhe , Hou Yanglong , Zhang Chenzhen , Yin Han , Sun Shouheng 
Published: January 2014

AbstractControlling exchange coupling between hard magnetic and soft magnetic phases is the key to the fabrication of advanced magnets with tunable magnetism and high energy density. Using FePt as an example, control over the magnetism in exchange‐coupled nanocomposites of hard magnetic face‐centered tetragonal (fct) FePt and soft magnetic Co (or Ni, Fe2C) is shown. The dispersible hard magnetic fct‐FePt nanoparticles are first prepared with their coercivity (Hc) reaching 33 kOe. Then core/shell fct‐FePt/Co (or Ni, Fe2C) nanoparticles are synthesized by reductive thermal decomposition of the proper metal precursors in the presence of fct‐FePt nanoparticles. These core/shell nanoparticles are strongly coupled by exchange interactions and their magnetic properties can be rationally tuned by the shell thickness of the soft phase. This work provides an ideal model system for the study of exchange coupling at the nanoscale, which will be essential for building superstrong magnets for various permanent magnet applications in the future.
Ascorbic Acid as an Initiator for the Direct CH Arylation of (Hetero)arenes with Anilines Nitrosated In Situ
Authors: Crisóstomo Fernando Pinacho , Martín Tomás , Carrillo Romen 
Published: January 2014

AbstractAscorbic acid (vitamin C) has been used as a radical initiator in a metal‐free direct CH arylation of (hetero)arenes. Starting from an aniline, the corresponding arenediazonium ion is generated in situ and immediately reduced by vitamin C to an aryl radical that undergoes a homolytic aromatic substitution with a (hetero)arene. Notably, neither heating nor irradiation is required. This procedure is mild, operationally simple, and constitutes a greener approach to arylation.
Aqueous polyacrylate/poly(silicone‐co‐acrylate) emulsion coated fertilizers for slow nutrient‐release application
Authors: Shen Yazhen , Du Changwen , Zhou Jianmin 
Published: January 2014

ABSTRACTWaterborne polyacrylate/poly(silicone‐co‐acrylate) emulsions were synthesized to develop coated fertilizers. The effects of the n‐butyl acrylate (BA)/methyl methacrylate (MMA) ratio, vinyltriethoxysilane, and synthesis method on the water resistance, glass‐transition temperature, mechanical properties, and nutrient‐release profiles were investigated. The results show that miniemulsion polymerization with a BA/MMA ratio of 55:45 was the most suitable for slow nutrient‐release applications. Under these conditions, the preliminary solubility rate of the nutrient was about 3%, and the 30‐day cumulative nutrient release was 15% at 25°C. © 2014 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2014, 131, 40369.
Cryo‐preservation for the repeated use of a PDMS prepolymer
Authors: Ju Jongil 
Published: January 2014

ABSTRACTLeftover uncured polydimethylsiloxane (PDMS) polymer is generally discarded. In an effort to minimize this waste, we have developed a method for cryo‐preserving PDMS prepolymer involving a simple storage technique for the preservation and repeated use over 1 month. Aliquots of the uncured PDMS prepolymer were stored at −20 or −80°C, then conveniently and easily thawed at body temperature (37°C). Proposed cryo‐preservation was successfully evaluated using diverse biological and physical tests. This method of cryo‐preserving PDMS reduces both the material waste and labor of soft lithography process and may enable soft lithography to be environmentally friendly relative to previous methods. The method may be popularly accepted for application to a variety of common microdevice fabrication procedures. © 2014 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2014, 131, 40378.
High Level of Construal and Psychological Distance Reduce Melioration
Authors: Pick‐Alony Rotem , Liberman Nira , Trope Yaacov 
Published: January 2014

ABSTRACTWe examined how level of construal and psychological distance affected performance in a task in which value of alternatives depended on frequency of choice. Melioration, a sub‐optimal choice strategy that fails to take into account such value changes, has been found to be prevalent and difficult to change. Participants repeatedly chose between two buttons to earn as many coins as possible. Button A earned N coins, button B earned N + 3 coins, and N was the number of A presses in the last five trials. In this situation, B has a higher immediate payoff, but because choosing A increases the return from both buttons for the next five trials, maximizing A choices is the optimal strategy. We predicted that because a global perspective is needed to appreciate the dependency of value on frequency of choice, frequency of choosing the globally maximizing alternative (A) would increase when participants apply a higher level of construal and assume a more psychologically distal perspective. Study 1 manipulated construal level through segmenting the sequence of trials into segments of different size, with bigger segments representing higher level of construal. In Study 2, participants played a practice game, and we manipulated the probability of playing the actual game. Both a higher level of construal and a lower probability of playing the actual game (higher distance) increased the number of A choices. These results suggest that a broad perspective that is induced by high level of construal or by psychological distancing may reduce sub‐optimal, meliorating choice. Copyright © 2014 John Wiley & Sons, Ltd.
ZEBRA cell‐penetrating peptide as an efficient delivery system in Candida albicans
Authors: Marchione Roberta , Daydé David , Lenormand Jean‐Luc , Cornet Muriel 
Published: January 2014

AbstractThere is increasing interest in drug delivery systems, such as nanoparticles, liposomes, and cell‐penetrating peptides, for the development of new antimicrobial treatments. In this study, we investigated the transduction capacity of a carrier peptide derived from the Epstein–Barr virus ZEBRA protein in the pathogenic fungus Candida albicans. ZEBRA‐minimal domain (MD) was able to cross the cell wall and cell membrane, delivering eGFP to the cytoplasm. Uptake into up to 70% of the cells was observed within two hours, without toxicity. This new delivery system could be used in C. albicans as a carrier for different biological molecules including peptides, proteins, and nucleic acids. Thereby, in antifungal therapy, MD may carry promising bioactive fungal inhibitors that otherwise penetrate poorly into the cells. Furthermore, MD will be of interest for deciphering molecular pathways involving cell‐cycle control in yeast or signaling pathways. Short interfering peptides could be internalized using MD, providing new tools for the inhibition of metabolic or signaling cascades essential for the growth and virulence of C. albicans, such as yeast‐to‐hyphae transition, cell wall remodeling, stress signaling and antifungal resistance. These findings create new possibilities for the internalization of cargo molecules, with applications for both treatment and functional analyses.
A column‐switching HPLC‐MS/MS method for mucopolysaccharidosis type I analysis in a multiplex assay for the simultaneous newborn screening of six lysosomal storage disorders
Authors: Gucciardi Antonina , Legnini Elisa , Di Gangi Iole Maria , Corbetta Carlo , Tomanin Rosella , Scarpa Maurizio , Giordano Giuseppe 
Published: January 2014

ABSTRACTLysosomal storage disorders comprise a group of rare genetic diseases in which a deficit of specific hydrolases leads to the storage of undegraded substrates in lysosomes. Impaired enzyme activities can be assessed by MS/MS quantification of the reaction products obtained after incubation with specific substrates. In this study, a column‐switching HPLC‐MS/MS method for multiplex screening in dried blood spot of the lysosomal enzymes activities was developed. Mucopolysaccharidosis type I, Fabry, Gaucher, Krabbe, Niemann–Pick A/B and Pompe diseases were simultaneously assayed. Dried blood spots were incubated with substrates and internal standards; thereafter, supernatants were collected with minor manipulations. Samples were injected, trapped into an online perfusion column and, by a six‐port valve, switched online through the C18 analytical column to perform separation of metabolites followed by MS/MS analysis. A total of 1136 de‐identified newborn screening samples were analyzed to determine references for enzymes activity values. As positive controls, we analyzed dried blood spots from three patients with Pompe, one with Fabry, one with Krabbe disease and two with MPS I, and in all cases the enzyme activities were below the cutoff values measured for newborns, except for an MPS I patient after successful hematopoietic stem cell transplantation. Copyright © 2014 John Wiley & Sons, Ltd.
Enhanced cardiac perception predicts impaired performance in the Iowa Gambling Task in patients with panic disorder
Authors: Wölk Julian , Sütterlin Stefan , Koch Stefan , Vögele Claus , Schulz Stefan M. 
Published: January 2014

AbstractObjectiveSomatic marker theory predicts that somatic cues serve intuitive decision making; however, cardiovascular symptoms are threat cues for patients with panic disorder (PD). Therefore, enhanced cardiac perception may aid intuitive decision making only in healthy individuals, but impair intuitive decision making inPDpatients.MethodsPDpatients and age‐ and sex‐matched volunteers without a psychiatric diagnosis (n = 17, respectively) completed the Iowa Gambling Task (IGT) as a measure of intuitive decision making. Interindividual differences in cardiac perception were assessed with a common mental‐tracking task.ResultsIn line with our hypothesis, we found a pattern of opposing associations (Fisher'sZ = 1.78,P = 0.04) of high cardiac perception with improvedIGT‐performance in matched control‐participants (r = 0.36,n = 14) but impairedIGT‐performance inPDpatients (r = −0.38,n = 13).ConclusionInteroceptive skills, typically assumed to aid intuitive decision making, can have the opposite effect inPDpatients who experience interoceptive cues as threatening, and tend to avoid them. This may explain whyPDpatients frequently have problems with decision making in everyday life. Screening of cardiac perception may help identifying patients who benefit from specifically tailored interventions.
Development of an R‐Selective Amine Oxidase with Broad Substrate Specificity and High Enantioselectivity
Authors: Heath Rachel S. , Pontini Marta , Bechi Beatrice , Turner Nicholas J. 
Published: January 2014

AbstractAmine oxidases are useful bio‐catalysts for the synthesis of enantiomerically pure 1°, 2° and 3° chiral amines. Enzymes in this class (e.g., MAO‐N from Aspergillus niger) reported previously have been shown to be highly S selective. Herein we report the development of an enantiocomplementary R‐selective amine oxidase based on 6‐hydroxy‐D‐nicotine oxidase (6‐HDNO) with broadened substrate scope and high enantioselectivity. The engineered 6‐HDNO enzyme has been applied to the preparative deracemisation of a range of racemic amines to yield S‐configured products, for example, (S)‐nicotine, in high ee.
NOx Reduction at Near Ambient Temperatures and Under Lean‐Burn Conditions on Modified Pd Surfaces
Authors: Roy Kanak , Gopinath Chinnakonda S. 
Published: January 2014

AbstractPalladium surfaces that are modified with O atoms in the subsurface broaden the NO reduction temperature regime up to 325 K with O2‐rich NO+H2+O2 compositions. Compared to virgin Pd surfaces, up to 150 % higher deNOx catalytic activity was observed with modified Pd surfaces at the reaction maximum. Molecular beam instrument and ambient‐pressure photoelectron spectroscopy were employed to follow the kinetic and surface changes. These results open up a possibility to realize the cold‐start reduction of NOx (deNOx). DeNOx activity reported in the literature with supported Pd catalysts after a simple calcination in air compares well with our present observations. Surface modification is likely to demonstrate a high potential for other catalytic reactions at relatively low temperatures.
First Highly Efficient and Photostable E and C Derivatives of 4,4‐Difluoro‐4‐bora‐3a,4a‐diaza‐s‐indacene (BODIPY) as Dye Lasers in the Liquid Phase, Thin Films, and Solid‐State Rods
Authors: Duran‐Sampedro Gonzalo , Esnal Ixone , Agarrabeitia Antonia R. , Bañuelos Prieto Jorge , Cerdán Luis , García‐Moreno Inmaculada , Costela Angel , Lopez‐Arbeloa Iñigo , Ortiz María J. 
Published: January 2014

AbstractA new library of E‐ and C‐4,4‐difluoro‐4‐bora‐3a,4a‐diaza‐s‐indacene (BODIPY) derivatives has been synthesized through a straightforward protocol from commercially available BODIPY complexes, and a systematic study of the photophysical properties and laser behavior related to the electronic properties of the B‐substituent group (alkynyl, cyano, vinyl, aryl, and alkyl) has been carried out. The replacement of fluorine atoms by electron‐withdrawing groups enhances the fluorescence response of the dye, whereas electron‐donor groups diminish the fluorescence efficiency. As a consequence, these compounds exhibit enhanced laser action with respect to their parent dyes, both in liquid solution and in the solid phase, with lasing efficiencies under transversal pumping up to 73 % in liquid solution and 53 % in a solid matrix. The new dyes also showed enhanced photostability. In a solid matrix, the derivative of commercial dye PM597 that incorporated cyano groups at the boron center exhibited a very high lasing stability, with the laser emission remaining at the initial level after 100 000 pump pulses in the same position of the sample at a 10 Hz repetition rate. Distributed feedback laser emission was demonstrated with organic films that incorporated parent dye PM597 and its cyano derivative. The films were deposited onto quartz substrates engraved with appropriate periodical structures. The C derivative exhibited a laser threshold lower than that of the parent dye as well as lasing intensities up to three orders of magnitude higher.
Enantioselective Surface Plasmon Resonance Sensor Based on C60 Fullerene‐Glutathione Self‐Assembled Monolayer (SAM)
Authors: Stefan‐van Staden Raluca‐Ioana 
Published: January 2014

ABSTRACTA novel enantioselective surface plasmon resonance (SPR) sensor based on a self‐assembled monolayer of C60 fullerene as the chiral selector is proposed. A binding assay, apparent affinity constant, and apparent dissociation binding constant were used to analyze and study the enantioselectivity of C60 fullerene‐glutathione film for L‐histidine, which was chosen as the model analyte. The apparent affinity constant for the complex formed by L‐histidine with C60 fullerene‐glutathione film was 5.2 x 109 M‐1. The proposed SPR sensor can be used for the assay of L‐histidine in the 10‐10 – 10‐7 mol/L concentration range. Chirality 26:129–131, 2014. © 2014 Wiley Periodicals, Inc.
Clinical Implications and Correlates of Q Waves in Patients With ST‐Elevation Myocardial Infarction Treated With Fibrinolysis: Observations from the CLARITY‐TIMI 28 Trial
Authors: Waks Jonathan W. , Sabatine Marc S. , Cannon Christopher P. , Morrow David A. , Gibson C. Michael , Wiviott Stephen D. , Giugliano Robert P. , Sloan Sarah , Scirica Benjamin M. 
Published: January 2014

AbstractBackgroundThe relationships between Q waves that appear during the acute phase of ST‐elevation myocardial infarction (STEMI), clinical characteristics, ST‐segment resolution (STRes), and clopidogrel therapy in patients treated with fibrinolysis are not well described.HypothesisWe hypothesized that Q waves would be associated with less successful reperfusion and increased cardiovascular events.MethodsIn the CLARITY‐TIMI 28 trial, 3491 STEMI patients treated with fibrinolysis were randomized to clopidogrel or placebo. Electrocardiograms were evaluated for STRes post‐fibrinolysis and the presence of pathologic Q waves during the index hospitalization in 3322 patients.ResultsQ waves were identified in 2045 patients (61.6%) prior to discharge and were associated with increased odds of congestive heart failure (CHF) (adjusted odds ratio [ORadj]: 2.10, P = 0.002) or the composite of cardiovascular death/CHF at 30 days (ORadj: 2.08, P ≤ 0.001). Q waves were associated with lower odds of Thrombolysis in Myocardial Infarction [TIMI] flow grade 2 to 3 (ORadj: 0.78, P = 0.028), TIMI myocardial perfusion grade 3 (ORadj: 0.83, P = 0.029), and complete STRes at 90 minutes (ORadj: 0.80, P = 0.030). Patients with both a Q wave and incomplete STRes 90 minutes after fibrinolysis were at higher risk for cardiovascular death or CHF (11.1%) than patients with no Q wave and at least partial STRes (1.9%). Overall, clopidogrel tended to be equally or more effective in patients without Q waves compared to those with Q waves.ConclusionsAmong STEMI patients treated with fibrinolysis, evaluating for Q waves prior to discharge is a simple method of assessing for less successful reperfusion and an increased risk of adverse 30‐day cardiovascular outcomes. The combination of Q waves and 90‐minute STRes allows additional risk refinement.
Diagnostic Performance of Copeptin in Patients With Acute Nontraumatic Chest Pain: BWH‐TIMI ED Chest Pain Study
Authors: Sukul Devraj , Bonaca Marc P. , Ruff Christian T. , Kosowsky Joshua , Conrad Michael , Murphy Sabina A. , Sabatine Marc S. , Jarolim Petr , Morrow David A. 
Published: January 2014

AbstractBackgroundArginine‐vasopressin (AVP) is an acute marker of physiologic stress. Copeptin is the C‐terminal fragment of vasopressin precursor hormone that is more easily measured than AVP. Studies assessing the utility of copeptin in the diagnosis of myocardial infarction (MI) have demonstrated mixed results.HypothesisThe aim of this study was to test the hypothesis that copeptin improves diagnostic performance when added to troponin for detecting MI in patients presenting to the emergency department with nontraumatic chest pain.MethodsWe measured copeptin, local cardiac troponin I (local cTnI), and a contemporary sensitive cardiac troponin I (sensitive cTnI) at presentation and serially in patients who presented with acute chest pain. A copeptin cutoff of 14 pmol/L was utilized.ResultsMI was diagnosed in 25.7% of patients. Noncoronary acute cardiopulmonary causes of chest pain occurred in 12.8%. Patients with MI had significantly higher copeptin levels than patients with noncardiac chest pain (P < 0.001). The area under the receiver operating characteristic curve (AUC) for copeptin was 0.60 (95% confidence interval: 0.54‐0.66), significantly less than the AUC for local cTnI (0.92) or sensitive cTnI (0.96). The combination of copeptin with either the local or sensitive troponin assay (c‐statistics 0.92 and 0.95, respectively) did not significantly improve the AUC as compared to either troponin assay alone. This finding persisted in the subgroup of early presenters (≤6 hours from symptom onset).ConclusionsCopeptin did not improve the diagnostic performance for detecting MI when used alone or in combination with a contemporary sensitive cTnI assay, though our cohort had relatively few early presenters.