bluuebunny/crossref_metadata_2025_split huggingface dataset:
Oxo–Group‐14‐Element Bond Formation in Binuclear Uranium(V) Pacman Complexes
Authors: Jones Guy M. , Arnold Polly L. , Love Jason B. 
Published: June 2013

AbstractSimple and versatile routes to the functionalization of uranyl‐derived UV–oxo groups are presented. The oxo‐lithiated, binuclear uranium(V)–oxo complexes [{(py)3LiOUO}2(L)] and [{(py)3LiOUO}(OUOSiMe3)(L)] were prepared by the direct combination of the uranyl(VI) silylamide “ate” complex [Li(py)2][(OUO)(N”)3] (N”=N(SiMe3)2) with the polypyrrolic macrocycle H4L or the mononuclear uranyl (VI) Pacman complex [UO2(py)(H2L)], respectively. These oxo‐metalated complexes display distinct UO single and multiple bonding patterns and an axial/equatorial arrangement of oxo ligands. Their ready availability allows the direct functionalization of the uranyl oxo group leading to the binuclear uranium(V) oxo–stannylated complexes [{(R3Sn)OUO}2(L)] (R=nBu, Ph), which represent rare examples of mixed uranium/tin complexes. Also, uranium–oxo‐group exchange occurred in reactions with [TiCl(OiPr)3] to form U‐OC bonds [{(py)3LiOUO}(OUOiPr)(L)] and [(iPrOUO)2(L)]. Overall, these represent the first family of uranium(V) complexes that are oxo‐functionalised by Group 14 elements.
ChemInform Abstract: Investigation of Fe Incorporation in LnCr2Al20 (Ln: La, Gd, Yb) with 57Fe Moessbauer and Single Crystal X‐Ray Diffraction.
Authors: Treadwell LaRico J. , McAlpin Jacob D. , Schmitt Devin C. , Kangas Michael J. , Sougrati Moulay T. , Haldolaarachchige Neel , Young David P. , Jumas Jean‐Claude , Chan Julia Y. 
Published: June 2013

AbstractLnCr2Al20‐xFex (Ln: La, Gd, Yb; x = 0.1, 0.2, 0.3) are prepared by flux reaction of the elements (alumina crucible in an evacuated silica tube, 1000 °C, 1 d).
ChemInform Abstract: Single‐Crystal Structure Determination and Spectroscopic Characterization of KSr4(BO3)3.
Authors: Sohr Gerhard , Clara Doris , Huppertz Hubert 
Published: June 2013

AbstractSingle crystals of the title compound are prepared from a stoichiometric mixture of K2CO3, SrCO3, and H3BO3 (5% Au/95% Pt crucible, 900 °C, 2 d) followed by high‐pressure treatment in a Walker‐type multi‐anvil apparatus (3 GPa, 1300 °C, 10 min).
ChemInform Abstract: Asymmetric Rearrangement of Racemic Epoxides Catalyzed by Chiral Broensted Acids.
Authors: Zhuang Minyang , Du Haifeng 
Published: June 2013

AbstractThe chiral Broensted acid catalyzed asymmetric 1,2‐rearrangement of racemic epoxides (I) and (III) via a hydrogen‐shift process is described.
ChemInform Abstract: Direct Arylation of Phenanthroline Derivatives via Oxidative C—H/C—H Cross‐Coupling: Synthesis and Discovery of Excellent Ligands.
Authors: Li Bijin , Qin Xurong , You Jingsong , Cong Xuefeng , Lan Jingbo 
Published: June 2013

AbstractA protocol for the synthesis of aryl functionalized phenanthrolines (I) is developed.
ChemInform Abstract: Nickel—Butadiene Catalytic System for the Cross‐Coupling of Bromoalkanoic Acids with Alkyl Grignard Reagents: A Practical and Versatile Method for Preparing Fatty Acids.
Authors: Iwasaki Takanori , Higashikawa Kiyokazu , Reddy Vutukuri P. , Ho Willbe W. S. , Fujimoto Yukari , Fukase Koichi , Terao Jun , Kuniyasu Hitoshi , Kambe Nobuaki 
Published: June 2013

AbstractGrignard reagents with long alkyl chains are difficult to handle requiring the reverse‐addition strategy of the Grignard reagents, generated in situ, to the tethered bromocarboxylic acids [viz.
ChemInform Abstract: Direct ortho‐Arylation of ortho‐Substituted Benzoic Acids: Overriding Pd‐Catalyzed Protodecarboxylation.
Authors: Arroniz Carlos , Ironmonger Alan , Rassias Gerry , Larrosa Igor 
Published: June 2013

AbstractThe presence of potassium carbonate prevents decarboxylation in Pd‐catalyzed ortho‐arylations of sterically hindered benzoic acids, making 2‐aryl‐6‐substituted benzoic acids easily accessible.
ChemInform Abstract: Catalyst‐Free, Direct, High Regio‐ and Chemoselective Conversion of Epoxides to Vicinal Haloesters under Mild, Neutral and Solvent‐Free Conditions.
Authors: Aghapour Ghasem , Hatefipour Razieh 
Published: June 2013

AbstractTitle reaction providing haloesters [(III) and (VIII)] is proved to be suitable for preparation of vic‐haloesters even in the presence of many functional groups with high regio‐ and chemoselectivity under mild and neutral reaction conditions.
ChemInform Abstract: Molecular Iodine in Aqueous Ammonia: Oxidative Fragmentation of Oxiranes to Nitriles.
Authors: Jadhav Ravindra R. , Akamanchi Krishnacharya G. 
Published: June 2013

AbstractA new, more convenient, and cost‐effective method for the oxidative C—C fragmentation of oxiranes to nitriles using nonexplosive molecular iodine is developed.
ChemInform Abstract: Pd‐Catalyzed Thiocarbonylation with Stoichiometric Carbon Monoxide: Scope and Applications.
Authors: Burhardt Mia N. , Taaning Rolf H. , Skrydstrup Troels 
Published: June 2013

AbstractThe reported method features low catalyst loading (1 mol%), applicability to both electron‐rich and ‐deficient iodoarenes as well as aryl and alkyl thiols.
ChemInform Abstract: Fused Dihydrofurans from the One‐Pot, Three‐Component Reaction of 1,3‐Cyclohexanedione, Iodobenzene Diacetate and Alkenes.
Authors: Kalpogiannaki Dimitra , Martini Catherine‐Irene , Nikopoulou Aggeliki , Nyxas John A. , Pantazi Vassiliki , Hadjiarapoglou Lazaros P. 
Published: June 2013

AbstractThe presented cycloaddition reaction exhibits wide generality and proceeds with high regioselectivity.
ChemInform Abstract: Synthesis of 2‐Aryl‐3‐fluoro‐5‐silylthiophenes via a Cascade Reactive Sequence.
Authors: Hirotaki Kensuke , Hanamoto Takeshi 
Published: June 2013

AbstractThe first successful SN2′‐type reaction of 2‐bromo‐3,3,3‐trifluoropropene (II) with various thiols is reported.
ChemInform Abstract: Iridium‐Catalyzed Asymmetric Hydrogenation of α‐Alkylidene Succinimides.
Authors: Liu Yuanyuan , Zhang Wanbin 
Published: June 2013

AbstractThe synthetic application of the presented method is demonstrated by the synthesis of 3‐benzyl pyrrolidines with high enantioselectivities [e.g. (III)].
ChemInform Abstract: C2‐Symmetric Cyclic Selenium‐Catalyzed Enantioselective Bromoaminocyclization.
Authors: Chen Feng , Tan Chong Kiat , Yeung Ying‐Yeung 
Published: June 2013

AbstractThis is the first Lewis basic selenium‐catalyzed asymmetric bromocyclization of trisubstituted olefinic amides.
ChemInform Abstract: Synthesis of 3,5‐Disubstituted Pyrazoles via Cope‐Type Hydroamination of 1,3‐Dialkynes.
Authors: Wang Liangguang , Yu Xiaoqiang , Feng Xiujuan , Bao Ming 
Published: June 2013

AbstractThe facile, mild, and efficient method allows the access to a wide range of target compounds.
ChemInform Abstract: Synthesis, Crystal Structure and Antibacterial Activity of New Highly Functionalized Ionic Compounds Based on the Imidazole Nucleus.
Authors: Bahnous Mebarek , Bouraiou Abdelmalek , Chelghoum Meryem , Bouacida Sofiane , Roisnel Thierry , Smati Farida , Bentchouala Chafia , Gros Philippe C. , Belfaitah Ali 
Published: June 2013

AbstractA variety of new highly functionalized imidazolium salts (III) are synthesized and evaluated for their antibacterial activity.
ChemInform Abstract: Synthesis, Chemical Properties, and Biological Evaluations of Some Twin‐Drug Type C2‐Symmetrical Derivatives.
Authors: Fujisaki Fumiko , Usami Haruka , Nakashima Saya , Nishida Sho , Fujioka Toshihiro , Kashige Nobuhiro , Miake Fumio , Sumoto Kunihiro 
Published: June 2013

AbstractThe synthesis of five twin‐drug type and two triplet‐drug type derivatives is described.
ChemInform Abstract: A Cationic High‐Valent Cp*CoIII Complex for the Catalytic Generation of Nucleophilic Organometallic Species: Directed C—H Bond Activation.
Authors: Yoshino Tatsuhiko , Ikemoto Hideya , Matsunaga Shigeki , Kanai Motomu 
Published: June 2013

AbstractThe air‐ and moisture‐stable title catalyst is readily synthesized as solid in 24% overall yield from CoCl2 in gram quantities without the use of any expensive reagents.
ChemInform Abstract: A Concise One‐Pot Synthesis of Trifluoromethyl‐Containing 2,6‐Disubstituted 5,6,7,8‐Tetrahydroquinolines and 5,6,7,8‐Tetrahydronaphthyridines.
Authors: Johnson Russell J. , O'Mahony Donogh J. R. , Edwards William T. , Duncton Matthew A. J. 
Published: June 2013

AbstractTitle compounds (III), (V), (VII) and (IX) are prepared via a three‐step/one‐pot pyridine‐annulation strategy.
ChemInform Abstract: One‐Pot Synthesis of 1H‐Indazolo[2,1‐b]phthalazinetrione Catalyzed by Magnetic Room Temperature Dicationic Ionic Liquid under Solvent‐Free Conditions.
Authors: Godajdar Bijan Mombani , Kiasat Ali Reza , Hashemi Mohammad Mahmoodi 
Published: June 2013

AbstractA simple, green, efficient, and novel synthesis of the title compounds (IV) via a multi‐component reaction under solvent free conditions is developed.
ChemInform Abstract: Discovery of Novel Inhibitors Targeting the Mycobacterium tuberculosis O‐Acetylserine Sulfhydrylase (CysK1) Using Virtual High‐Throughput Screening.
Authors: Kumar Variam Ullas Jean , Poyraz Oemer , Saxena Shalini , Schnell Robert , Yogeeswari Perumal , Schneider Gunter , Sriram Dharmarajan 
Published: June 2013

AbstractA simple and highly efficient microwave‐assisted synthesis of a library of pyrimidothiazolopyrimidinedione (VII) and related thione derivatives (IX) as potential antitubercular agents is given.
ChemInform Abstract: Synthesis of New Derivatives of Pyrimido[5,4‐e][1,2,4]triazolo[3,4‐b][1,3,4]thiadiazine and Their Enzyme Inhibitory Activity Assessment on Soybean 15‐Lipoxygenase.
Authors: Bakavoli Mehdi , Seyedi Seyed Mohammad , Shiri Ali , Saberi Sattar , Gholami Mahmoud , Sadeghian Hamid 
Published: June 2013

AbstractNew compounds (V) and (VI) show very low inhibitory activities towards soybean 15‐lipoxygenase.
ChemInform Abstract: Synthesis of Silyl‐Substituted Anthracene Derivatives via Birch‐Type Silylation.
Authors: Kanno Ken‐ichiro , Maemura Yumika , Kobayashi Naotaka , Kyushin Soichiro 
Published: June 2013

AbstractThe Birch‐type silylation of anthracene affords hexasilylated hexahydroanthracene (III) as a single stereoisomer.
ChemInform Abstract: Transition‐Metal‐Free Synthesis of Unsymmetrical Diaryl Chalcogenides from Arenes and Diaryl Dichalcogenides.
Authors: Prasad Ch. Durga , Balkrishna Shah Jaimin , Kumar Amit , Bhakuni Bhagat Singh , Shrimali Kaustubh , Biswas Soumava , Kumar Sangit 
Published: June 2013

AbstractIn some cases the reaction with diphenyldisulfide affords dithiolated products [cf.
ChemInform Abstract: A Concise Formal Synthesis of (‐)‐Hamigeran B (XIV).
Authors: Jiang Biao , Li Ming‐ming , Xing Ping , Huang Zuo‐gang 
Published: June 2013

AbstractThe sequence starts with the synthesis of cyclopentenone (IV) by intermolecular Pauson—Khand reaction of (I) with an excess of Me2S as promoter.
ChemInform Abstract: Total Synthesis of Cyclic Heptapeptide Rolloamide B (I).
Authors: El Khatib Mirna , Elagawany Mohamed , Caliskan Eray , Davis Emily Faith , Faidallah Hassan M. , El‐feky Said A. , Katritzky Alan R. 
Published: June 2013

AbstractThe work features solution phase benzotriazole‐mediated peptide synthesis ligating native amino acids.
ChemInform Abstract: Novel Antitumor Agent, Trilacunary Keggin‐Type Tungstobismuthate, Inhibits Proliferation and Induces Apoptosis in Human Gastric Cancer SGC‐7901 Cells.
Authors: Wang Lu , Zhou Bai‐Bin , Yu Kai , Su Zhan‐Hua , Gao Song , Chu Li‐Li , Liu Jia‐Ren , Yang Guo‐Yu 
Published: June 2013

AbstractYellow (Himi)2 [(W(OH)2)2(Mn (H2O)3)2(Na3 (H2O)14)(BiW9O33)2] ·16H2O (I) (imi: imidazole) is synthesized by reaction of Na2WO4·2H2O, Bi(NO3)3·5H2O, imi, and MnCl2·6H2O (4.7:0.5:1:0.7 molar ratio) in water (stirring at 80 °C, 2 h; addn.
ChemInform Abstract: Silica Monoliths with Hierarchical Porosity Obtained from Porous Glasses
Authors: Inayat Alexandra , Reinhardt Bjoern , Uhlig Hans , Einicke Wolf‐Dietrich , Enke Dirk 
Published: June 2013

AbstractReview: synthetic strategies for the introduction of hierarchy into “classical” porous glass monoliths; 42 refs.
Effects of crosslinking in demulsifiers on their performance
Authors: Kailey Ishpinder , Blackwell Catherine , Behles Jacqueline 
Published: June 2013

AbstractChemical demulsification is the most widely used method for breaking water‐in‐diluted bitumen emulsions in oil sands processing. In this work, the properties and performance of six ethylene oxide (EO)–propylene oxide (PO) demulsifiers from three families were investigated. The demulsifiers were characterised by their relative solubility number (RSN) and number of EO–PO branches. The results showed that the performance of the demulsifiers is correlated to the starting base compound, number of EO–PO branches, RSN, oil/water interfacial tension (IFT), increase of molecular weight (MW) by incorporation of crosslinks in EO–PO branches and yield stress of underflow. An increase in MW by the incorporation of crosslinks in EO–PO block copolymers decreased the RSN value while improved the dehydration efficiency. Dynamic IFT measurements revealed that the higher adsorption of EO–PO block copolymers at the oil/water interface on crosslinking, which resulted in higher dehydration efficiencies. The yield stress of the underflow increased on crosslinking the EO–PO block copolymers due to the release of more water and solids to the underflow, which increased the number of aggregates present in the underflow, resulting in increased immobility and constriction and higher yield stress.
Lost productivity and burden of illness in cancer survivors with and without other chronic conditions
Authors: Dowling Emily C. , Chawla Neetu , Forsythe Laura P. , de Moor Janet , McNeel Timothy , Rozjabek Heather M. , Ekwueme Donatus U. , Yabroff K. Robin 
Published: June 2013

BACKGROUNDCancer survivors may experience long‐term and late effects from treatment that adversely affect health and limit functioning. Few studies examine lost productivity and disease burden in cancer survivors compared with individuals who have other chronic conditions or by cancer type.METHODSWe identified 4960 cancer survivors and 64,431 other individuals from the 2008‐2010 Medical Expenditure Panel Survey and compared multiple measures of disease burden, including health status and lost productivity, between conditions and by cancer site for cancer survivors. All analyses controlled for the effects of age, sex, race/ethnicity, and number of comorbid conditions.RESULTSOverall, in adjusted analyses in multiple models, cancer survivors with another chronic disease (heart disease or diabetes) experienced higher levels of burden compared with individuals with a history of cancer only, chronic disease only, and neither cancer, heart disease, nor diabetes across multiple measures (P < .05). Among cancer survivors, individuals with short survival cancers and multiple cancers consistently had the highest levels of burden across multiple measures (P < .0001).CONCLUSIONSCancer survivors who have another chronic disease experience more limitations and higher levels of burden across multiple measures. Limitations are particularly severe in cancer survivors with short survival cancer and multiple cancers. Cancer 2013;119:3393–401. © 2013 American Cancer Society.
Efferent connections of the parvalbumin‐positive (PV1) nucleus in the lateral hypothalamus of rodents
Authors: Celio Marco R. , Babalian Alexandre , Ha Quan Hue , Eichenberger Simone , Clément Laurence , Marti Christiane , Saper Clifford B. 
Published: June 2013

ABSTRACTA solitary cluster of parvalbumin‐positive neurons – the PV1 nucleus – has been observed in the lateral hypothalamus of rodents. In the present study, we mapped the efferent connections of the PV1 nucleus using nonspecific antero‐ and retrograde tracers in rats, and chemoselective, Cre‐dependent viral constructs in parvalbumin‐Cre mice. In both species, the PV1 nucleus was found to project mainly to the periaqueductal grey matter (PAG), predominantly ipsilaterally. Indirectly in rats and directly in mice, a discrete, longitudinally oriented cylindrical column of terminal fields (PV1‐CTF) was identified ventrolateral to the aqueduct on the edge of the PAG. The PV1‐CTF is particularly dense in the rostral portion, which is located in the supraoculomotor nucleus (Su3). It is spatially interrupted over a short stretch at the level of the trochlear nucleus and abuts caudally on a second parvalbumin‐positive (PV2) nucleus. The rostral and the caudal portions of the PV1‐CTF consist of axonal endings, which stem from neurons scattered throughout the PV1 nucleus. Topographically, the longitudinal orientation of the PV1‐CTF accords with that of the likewise longitudinally oriented functional modules of the PAG, but overlaps none of them. Minor terminal fields were identified in a crescentic column of the lateral PAG, as well as in the Edinger–Westphal, the lateral habenular, and the laterodorsal tegmental nuclei. So far, no obvious functions have been attributed to this small, circumscribed column ventrolateral to the aqueduct, the prime target of the PV1 nucleus.J. Comp. Neurol. 521:3133–3153, 2013. © 2013 Wiley Periodicals, Inc.
Neural systems language: A formal modeling language for the systematic description, unambiguous communication, and automated digital curation of neural connectivity
Authors: Brown Ramsay A. , Swanson Larry W. 
Published: June 2013

ABSTRACTSystematic description and the unambiguous communication of findings and models remain among the unresolved fundamental challenges in systems neuroscience. No common descriptive frameworks exist to describe systematically the connective architecture of the nervous system, even at the grossest level of observation. Furthermore, the accelerating volume of novel data generated on neural connectivity outpaces the rate at which this data is curated into neuroinformatics databases to synthesize digitally systems‐level insights from disjointed reports and observations. To help address these challenges, we propose the Neural Systems Language (NSyL). NSyL is a modeling language to be used by investigators to encode and communicate systematically reports of neural connectivity from neuroanatomy and brain imaging. NSyL engenders systematic description and communication of connectivity irrespective of the animal taxon described, experimental or observational technique implemented, or nomenclature referenced. As a language, NSyL is internally consistent, concise, and comprehensible to both humans and computers. NSyL is a promising development for systematizing the representation of neural architecture, effectively managing the increasing volume of data on neural connectivity and streamlining systems neuroscience research. Here we present similar precedent systems, how NSyL extends existing frameworks, and the reasoning behind NSyL's development. We explore NSyL's potential for balancing robustness and consistency in representation by encoding previously reported assertions of connectivity from the literature as examples. Finally, we propose and discuss the implications of a framework for how NSyL will be digitally implemented in the future to streamline curation of experimental results and bridge the gaps among anatomists, imagers, and neuroinformatics databases. J. Comp. Neurol. 521: 2889–2906, 2013. © 2013 Wiley Periodicals, Inc.
Enabling efficient and secure data sharing in cloud computing
Authors: Li Jingwei , Li Jin , Liu Zheli , Jia Chunfu 
Published: June 2013

SUMMARYWith the rapid development of cloud computing, more and more data are being centralized into remote cloud server for sharing, which raises a challenge on how to keep them both private and accessible. Although searchable encryption provides an efficient solution to support keyword‐based search directly on encrypted data, considering its application in file sharing, existing work depends on key sharing among authorized users, which inevitably causes the risks of key exposure and abuse. In this paper, aiming at enabling efficient and secure data sharing in cloud computing, we provide a generic construction for this purpose. The proposed construction is full‐featured: (i) It enables authorized users to perform keyword‐based search directly on encrypted data without sharing the unique secret key; and (ii) it provides two‐layered access control to limit unauthorized user's access to the shared data. On the basis of the proposed generic construction, we utilize the existing techniques on identity‐based broadcast encryption and public key searchable encryption to instantiate a concrete construction. Copyright © 2013 John Wiley & Sons, Ltd.
A New Multiresponsive Drug Delivery System using Smart Nanogels
Authors: Demirel Gökçen Birlik , von Klitzing Regine 
Published: June 2013

AbstractThis paper addresses the synthesis and characterization of a novel temperature‐ and pH‐responsive nanogel system based on poly(vinylcaprolactam‐co‐2‐dimethylaminoethyl methacrylate) [P(VCL‐co‐DMAEMA)] by using a surfactant‐free emulsion polymerization procedure for the multiresponsive drug delivery of hydrophobic drugs. The effects of solvent, monomer, pH, and temperature were studied to tailor the average particle hydrodynamic diameters and the polydispersity index of the final particles. According to dynamic light‐scattering measurements, the obtained nanogels show a narrow particle‐size distribution and their hydrodynamic diameters can be varied from 81 to 368 nm. The nanogels display a re‐entrant phase‐transition state, and the equilibrium volume swelling ratio of the nanogels decreases drastically down to 47 °C and then increases up to 65 °C. In addition, the nanogels show pH‐dependent behavior. They exhibit a maximum size at pH 5.0. Rhodamine B (RhB) was chosen as a model compound for drug loading and release studies from P(VCL‐co‐DMAEMA) on the basis of particles in different phosphate buffer solutions at different temperatures. The temperature/pH‐dependent cumulative release and ultrasound‐enhanced pulsatile release properties were investigated for RhB‐loaded nanogels for long‐term and one‐shot delivery. The nanogels display efficient delivery for both long‐term and one‐shot delivery systems. We provide here a proof of concept for the novel use of multiresponsive nanogels having an overall size below 200 nm as a cargo system for hydrophobic drugs and for controlled release mediated by temperature/pH and ultrasound.
Conformational Propensities of Intrinsically Disordered Proteins from NMR Chemical Shifts
Authors: Kragelj Jaka , Ozenne Valéry , Blackledge Martin , Jensen Malene Ringkjøbing 
Published: June 2013

AbstractThe realization that a protein can be fully functional even in the absence of a stable three‐dimensional structure has motivated a large number of studies describing the conformational behaviour of these proteins at atomic resolution. Here, we review recent advances in the determination of local structural propensities of intrinsically disordered proteins (IDPs) from experimental NMR chemical shifts. A mapping of the local structure in IDPs is of paramount importance in order to understand the molecular details of complex formation, in particular, for IDPs that fold upon binding or undergo structural transitions to pathological forms of the same protein. We discuss experimental strategies for the spectral assignment of IDPs, chemical shift prediction algorithms and the generation of representative structural ensembles of IDPs on the basis of chemical shifts. Additionally, we highlight the inherent degeneracies associated with the determination of IDP sub‐state populations from NMR chemical shifts alone.