bluuebunny/crossref_metadata_2025_split huggingface dataset:
Translation and psychometric evaluation of a French version of the Readiness for Hospital Discharge Scale
Authors: Mabire Cedric , Lecerf Thierry , Büla Christophe , Morin Diane , Blanc Genevieve , Goulet Celine 
Published: July 2015

Aims and objectivesTo evaluate the reliability and the factor structure of the Readiness for Hospital Discharge Scale – French version.BackgroundThe patient's perspective is essential when assessing risk for adverse events at hospital discharge. Developed in the USA, the Readiness for Hospital Discharge Scale is the only instrument that measures an individual's self‐perception of readiness before leaving the hospital. A French version of the Readiness for Hospital Discharge Scale was developed and validated.DesignCross‐sectional study.MethodsA convenience sample of 265 older inpatients from four medical units was selected. The translation and cultural adaptation of the scale involved experts in gerontology and the French language and included back translation. The items were semantically evaluated and pretested in 10 older inpatients. The scale's psychometric properties were internally validated by using confirmatory and exploratory factor analyses. Reliability was assessed by examining the internal consistency of its items.ResultsGoodness‐of‐fit indices of the confirmatory factor analyses were not adequate, but reliability was acceptable (Cronbach's α = 0·80). Exploratory factor analysis of the French version provided results close to those described for the English version, with three similar subscales (physical and emotional readiness,coping with medical treatmentandpersonal care), whereas the initially described Expected Support subscale was not identified in the French version.ConclusionThe Readiness for Hospital Discharge Scale – French version appears to be partially consistent with its original English version, but requires additional adaptation to fully take into account the Swiss context and culture to achieve its original aim.Relevance to clinical practiceAssessing patient readiness for hospital discharge before leaving hospital could help nurses to improve the discharge planning process and achieve better patient preparedness and care coordination.
Oral lichen planus: salival biomarkers cortisol, immunoglobulinA, adiponectin
Authors: Lopez‐Jornet Pia , Cayuela Cristina Aznar , Tvarijonaviciute Asta , Parra‐Perez Francisco , Escribano Damian , Ceron Jose 
Published: July 2015

BackgroundOral lichen planus (OLP) is a chronic mucocutaneous disease, inflammatory and autoimmune in character, in which the pathogenesis is not fully understood. Psychological stress has also been implicated in triggering or exacerbating the disease.ObjectiveThe aim of this study was to evaluate the psychological profile, sleep, and salivary biological markers—cortisol, immunoglobinA(IgA), and adiponectin – in patients with oral lichen planus (OLP).MethodsThe sample consisted of 65 patients (33 withOLPand 32 control patients). Patients completed hospital anxiety and depression scales (HADD,HADA). Questionnaires were used to assess sleepiness: thePittsburgh sleep quality index (PSQI) and theEpworth sleepiness scale (ESS). A visual analog scale (VAS) was used for rating pain. Unstimulated whole saliva was evaluated, together with total proteins: cortisol,IgA, and adiponectin.ResultsPatients withOLPobtained significantly higherHADAandPSQIscores than control subjects (P = 0.001,P = 0.012, respectively). Total salivary protein (flow at rest) analysis found that total proteins were higher in theOLPgroup (P = 0.001). In theOLPgroup,IgAwas 80.3 ± 51.3 vs. the control group 48.9 ± 32.8 (P = 0.005). Mean cortisol was 0.5 ± 0.3 μg/dl in theOLPgroup vs. 0.4 ± 0.2 μg/dl in the control group (P = 0.010). TheOLPgroup showed a correlation between theHADAvariable and pain (r = 0.358;P = 0.041),HADD(r = 0.568;P = 0.001), andPSQI(r = 0.537;P = 0.001).ConclusionsOLPpatients presented worse psychological profiles and sleep disturbances, as well as higher values forIgA, cortisol, and total proteins than control subjects.
Effect of feeding guanidinoacetic acid and L‐arginine on the fertility rate and sperm penetration in the perivitelline layer of aged broiler breeder hens
Authors: Sharideh H. , Esmaeile Neia L. , Zaghari M. , Zhandi M. , Akhlaghi A. , Lotfi L. 
Published: July 2015

SummaryTwo experiments were conducted to evaluate the effects of feeding guanidinoacetic acid (GAA) and L‐arginine (ARG) on fertility and sperm penetration (SP) rate of broiler breeder hens. In the first experiment, a total of 200 broiler breeder hens (Ross 308) aged 53 week were randomly allotted to four dietary treatments (0, 0.6, 1.2 and 1.8 g GAA/kg diet) with five replicates of 10 birds each. In the second experiment, 320 broiler breeder hens (Ross 308) were used from 53 to 62 weeks of age in a 2 × 4 factorial arrangement (0 or 1.2 g GAA/kg diet along with 0, 3, 6 or 9 g ARG/kg diet). The hens received a diet containing 2800 kcal ME/kg and 14% CP. Sixteen sexually mature Ross 308 breeder roosters (34 weeks old) were used to artificially inseminate the hens. Fertility of the hens was determined in 61 and 62 weeks of age. The sperm penetration holes in the inner perivitelline layer (IPL) overlying the germinal disc were enumerated on days 3 and 7 following each insemination. Adding GAA to the breeder diet increased the number of SPs in the IPL and fertility in both experiments (p < 0.01). The interactive effect of ARG and GAA on the SP and fertility was significant. Supplementary ARG increased the SP rate in the IPL (p < 0.01). In conclusion, dietary supplementation of GAA and ARG might be potentially used to improve the fertility of broiler breeder hens at the later phase of the egg production period.
Schenker's Theory of Criticism, circa 1911
Authors: BURGSTALLER GEORG 
Published: July 2015

ABSTRACT‘Art and Criticism’ (‘Kunst und Kritik’), an unpublished draft essay dating from 1911, is Schenker's theory of music criticism in all but name, revealing his wider views about the cultural practice of music journalism. As such, it can be read as the foundation for his subsequent thinking on the matter. It also offers a glimpse into how his thinking on a subject evolved: he filed the draft in a folder together with an eclectic assortment of notes with references to literary works, as well as clippings of newspaper articles on music, art and literary criticism by the foremost contributors to the public debate on criticism at the turn of the century. Through a close reading of both ‘Art and Criticism’ and its paper trail in the Schenker Archive, I seek to shed light on Schenker's thinking as a process by showing that he engaged with the thinkers of his time and demonstrating the extent to which his rejection of journalism was stimulated by the ideas of his contemporaries.
Case report: aneurysmal bone cyst of the mandibular condyle
Authors: Dunphy L. , O'Connell S. , Halsnad M. , Parmar S. 
Published: July 2015

AbstractAn aneurysmal bone cyst is a benign, expansive, osteolytic lesion consisting of blood‐filled cysts. It occurs rarely in the craniofacial region, more commonly affecting the long bones and the spine. We report a rare case affecting the mandibular condyle of a 65‐year‐old Caucasian male.
Competition in slow motion: the unusual case of benthic marine communities in the wake of the end‐Permian mass extinction
Authors: Hautmann Michael , Bagherpour Borhan , Brosse Morgane , Frisk Åsa , Hofmann Richard , Baud Aymon , Nützel Alexander , Goudemand Nicolas , Bucher Hugo 
Published: July 2015

AbstractChanges of community structure in response to competition usually take place on timescales that are much too short to be visible in the geological record. Here we report the notable exception of a benthic marine community in the wake of the end‐Permian mass extinction, which is associated with the microbial limestone facies of the earliestTriassic ofSouthChina. The newly reported fauna is well preserved and extraordinarily rich (30 benthic macroinvertebrate species, including the new speciesAstartella?stefaniae(Bivalvia) andEucochlis obliquecostata(Gastropoda)) and stems from an environmentally stable setting providing favourable conditions for benthic organisms. Whereas changes in the taxonomic composition are negligible over the observed time interval of 10–100 ka, three ecological stages are identified, in which relative abundances of initially rare species continuously increased at the cost of previously dominant species. Concomitant with the changes of dominant species is an increase in faunal evenness and heterogeneity. In the absence of both environmental and taxonomic changes, we attribute this pattern to the long‐term effects of interspecific competition, which acted at an unusually slow pace because the number of competing species and potential immigrants was dramatically reduced by the end‐Permian mass extinction. We suggest that these non‐actualistic conditions led to decreased rates of niche differentiation and hence to the delayed rediversification of benthos that characterizes the aftermath of the greatestPhanerozoic mass extinction event. A hyperbolic diversification model is proposed, which accounts for the positive relationship between the intensity of interspecific competition and the rate of niche differentiation and resolves the conundrum of delayed rediversification at a time when niche space was largely vacated.
Biochemical Characterization of the DASH‐Type Cryptochrome CryD From Fusarium fujikuroi
Authors: Castrillo Marta , Bernhardt Adrian , Ávalos Javier , Batschauer Alfred , Pokorny Richard 
Published: July 2015

AbstractProteins from the cryptochrome/photolyase family utilize UV‐A, blue or even red light to achieve such diverse functions as repair of DNA lesions by photolyases and signaling by cryptochromes. DASH‐type cryptochromes retained the ability to repair cyclobutane pyrimidine dimers (CPDs) in single‐stranded DNA regions in vitro. However, most organisms possess conventional CPD photolyases responsible for repair of these lesions in vivo. Recent work showed that the DASH‐type cryptochrome CryD plays a regulatory role in diverse light‐dependent processes in Fusarium fujikuroi. Here, we report our in vitro studies on heterologously expressed FfCryD. The purified protein contains N5,N10‐methenyltetrahydrofolate and flavin adenine dinucleotide as cofactors. Photoreduction and DNA photorepair experiments confirmed that FfCryD is active in light‐driven electron transfer processes. However, the protein showed comparable affinities for CPD‐comprising and undamaged DNA probes. Surprisingly, after purification, full‐length FfCryD as well as a truncated version containing only the PHR domain bound RNA which influenced their behavior in vitro. Moreover, binding of FfCryD to RNA indicates a putative role in RNA metabolism or in posttranscriptional control of gene expression.
Sexual disinhibition and dementia
Authors: Cipriani Gabriele , Ulivi Martina , Danti Sabrina , Lucetti Claudio , Nuti Angelo 
Published: July 2015

AbstractTo describe inappropriate sexual behaviour (ISB) observed in patients with dementia, we conducted searches using the Cochrane Library, PubMed, and Web of Science to find relevant articles, chapters, and books published from 1950 to 2014. Search terms used included ‘hypersexuality’, ‘inappropriate sexual behaviors’, and ‘dementia’. Publications found through this indexed search were reviewed for further relevant references. Sexuality is a human's need to express intimacy, but persons with dementia may not know how to appropriately meet their needs for closeness and intimacy due to their decline in cognition. Generally, the interaction among brain, physical, psychological, and environmental factors can create what we call ISB. The most likely change in the sexual behaviour of a person with dementia is indifference. However, ISB in dementia appear to be of two types—intimacy‐seeking and disinhibited—that differ in their association with dementia type, dementia severity and, possibly, other concurrent behavioural disorder. Tensions develop from uncertainties regarding which, or when, behaviours are to be considered ‘inappropriate’ (i.e. improper) or abnormal. While most ISB occur in the moderate to severe stages of Alzheimer's dementia, they may also be seen in early stages of frontotemporal dementia because of the lack of insight and disinhibition. ISB are often better managed by non‐pharmacological means, as patients may be less responsive to psychoactive therapies, but non‐pharmacological interventions do not always stop the behaviour.
Evaluation of canine‐specific minocycline and doxycycline susceptibility breakpoints for meticillin‐resistant Staphylococcus pseudintermedius isolates from dogs
Authors: Hnot Melanie L. , Cole Lynette K. , Lorch Gwendolen , Papich Mark G. , Rajala‐Schultz Paivi J. , Daniels Joshua B. 
Published: July 2015

BackgroundUsing the US Clinical and Laboratory Standards Institute (CLSI) human tetracycline breakpoints to predict minocycline and doxycycline susceptibility of Staphylococcus pseudintermedius (SP) isolates from dogs is not appropriate because they are too high to meet pharmacokinetic/pharmacodynamic data using a standard dose. New breakpoints have been approved for doxycycline and proposed for minocycline. Revised breakpoints are four dilutions lower than tetracycline breakpoints, providing a more conservative standard for classification of isolates.Hypothesis/ObjectivesThe objectives of this study were to measure minimum inhibitory concentrations (MICs) of minocycline and doxycycline of 100 canine meticillin‐resistant SP clinical isolates, compare their susceptibilities to minocycline and doxycycline based on current and revised standards, and document their tetracycline resistance genes.MethodsE‐test strips were used to determine MICs. PCR was used to identify tet genes.ResultsUsing the human tetracycline breakpoint of MIC ≤ 4 μg/mL, 76 isolates were susceptible to minocycline and 36 isolates were susceptible to doxycycline. In contrast, using the proposed minocycline breakpoint (MIC ≤ 0.25 μg/mL) and approved doxycycline breakpoint (MIC ≤ 0.125 μg/mL), 31 isolates were susceptible to both minocycline and doxycycline. Thirty‐one isolates carried no tet genes, two had tet(K) and 67 had tet(M).Conclusions and clinical importanceUse of the human tetracycline breakpoints misclassified 45 and five of the isolates as susceptible to minocycline and doxycycline, respectively. PCR analysis revealed that 43 and five of the isolates classified as susceptible to minocycline and doxycycline, respectively, possessed the tetracycline resistance gene, tet(M), known to confer resistance to both drugs. These results underscore the importance of utilizing the proposed minocycline and approved doxycycline canine breakpoints in place of human tetracycline breakpoints.
Assessment of the relationships among coagulopathy, hyperfibrinolysis, plasma lactate, and protein C in dogs with spontaneous hemoperitoneum
Authors: Fletcher Daniel J. , Rozanski Elizabeth A. , Brainard Benjamin M. , de Laforcade Armelle M. , Brooks Marjory B. 
Published: July 2015

AbstractObjectiveTo relate coagulation and fibrinolysis derangements to shock severity as reflected by plasma lactate concentrations in dogs with spontaneous hemoperitoneum (SHP) and determine the impact on transfusions.DesignProspective, observational, case‐control study.SettingThree veterinary teaching hospitals.AnimalsTwenty‐eight client‐owned dogs with SHP and 28 breed‐ and age‐matched control dogs.InterventionsNone.Measurements and Main ResultsBlood samples for platelet counts, coagulation, and anticoagulant assays (prothrombin time, activated partial thromboplastin time, fibrinogen, antithrombin, and protein C, thromboelastography [TEG]), fibrinolysis testing (d‐dimer and TEG lysis parameters with and without the addition of 50 U/mL of tissue plasminogen activator [TEG LY30 measured with the addition of 50 U/mL of tPA to the blood sample, LY3050 and TEG LY60 measured with the addition of 50 U/mL of tPA to the blood sample, LY6050; LY30 and LY60]), and plasma lactate as an indicator of severity of shock were collected from SHP dogs at the time of diagnosis. SHP dogs were hypocoagulable (prolonged prothrombin time and activated partial thromboplastin time, decreased TEG maximum amplitude) and hyperfibrinolytic (increased LY3050 and TEG LY6050) compared to controls. The severity of hypocoagulability was related to protein C activity, while the severity of hyperfibrinolysis was related to plasma lactate concentration. Among the 18 dogs discharged from the hospital, LY3050 was significantly associated with the dose of fresh frozen plasma administered, but none of the parameters were associated with the dose of red blood cells administered.ConclusionsDogs with SHP have evidence of hypocoagulability, protein C deficiency, and hyperfibrinolysis. Parameters of hyperfibrinolysis were related to plasma lactate concentrations and volume of plasma transfused during hospitalization. These derangements resemble those found in people with acute coagulopathy of trauma and shock, and activation of protein C may be a common feature to both syndromes.
Parvoviral myocarditis in a 5‐week‐old Dachshund
Authors: Sime Tara A. , Powell Lisa L. , Schildt Julie C. , Olson Erik J. 
Published: July 2015

AbstractObjectiveTo describe a case of myocarditis associated with naturally occurring canine parvovirus type 2 (CPV‐2).Case SummaryA 5‐week‐old male intact Dachshund dog presented for acute respiratory distress. Limited diagnostic tests prior to the dog experiencing cardiopulmonary arrest included a lateral thoracic radiograph, which indicated cardiomegaly and diffuse unstructured pulmonary infiltrate. Necropsy was performed and results identified a lymphoplasmacytic myocarditis with positive CPV‐2 immunohistochemistry within the myocardium.Unique Information ProvidedThis report describes the natural occurrence of CPV‐2‐associated myocarditis. In addition to highlighting this rare form of canine parvovirus, cardiomyopathy in survivors of the acute viral myocarditis phase is reviewed.
Retrospective evaluation of xylitol ingestion in dogs: 192 cases (2007–2012)
Authors: DuHadway Meghan R. , Sharp Claire R. , Meyers Katherine E. , Koenigshof Amy M. 
Published: July 2015

AbstractObjectiveTo summarize the signalment, clinical signs, prevalence of decreased blood glucose concentration (BG), prevalence of increased liver values, treatment, and outcome in dogs known to have ingested xylitol.DesignRetrospective study from December 2007 to February 2012SettingThree university teaching hospitals.AnimalsOne hundred ninety‐two client‐owned dogs with known or suspected xylitol ingestion.InterventionsNone.Measurements and Main ResultsThe median ingested xylitol dose was 0.32 g/kg (range 0.03–3.64 g/kg). Clinical signs were present in 39 (20%) dogs on presentation to the veterinary teaching hospitals. The most common clinical sign was vomiting (n = 25), followed by lethargy (12). The median duration of clinical signs prior to presentation was 93 minutes (range 0–5,040 minutes). Dogs that developed clinical signs ingested a significantly higher dose of xylitol than those that were asymptomatic. Thirty dogs became hypoglycemic (BG ≤ 3.3 mmol/L [60 mg/dL]) at some time point during their hospitalization. When evaluating all dogs, there was a significant difference between the initial and lowest BGs. Thirty dogs had increased alanine aminotransferase activity or total serum bilirubin concentration. Dogs with increases in alanine aminotransferase activity or total serum bilirubin concentration had a significantly lower nadir BG. All dogs survived to discharge and 158 were known to be alive at 28 days. The rest were lost to follow up.ConclusionsThe prognosis for dogs evaluated by a veterinarian that ingest lower doses of xylitol and do not develop liver failure is excellent. Dogs ingesting xylitol should be hospitalized and monitored for variations in BG, because BG drops in most dogs following presentation. Additional studies are needed in dogs ingesting higher doses of xylitol before correlations between dose and the development of clinical signs or liver failure can be established. Treatment and prognosis for these dogs warrants further investigation.
Implementation of Safe Patient Handling in the U.S. Veterans Health System: A Qualitative Study of Internal Facilitators’ Perceptions
Authors: Elnitsky C. A. , Powell‐Cope G. , Besterman‐Dahan K. L. , Rugs D. , Ullrich P. M. 
Published: July 2015

ABSTRACTBackgroundAlthough the literature has noted the positive effects of facilitation in implementation research, little is known about what facilitators do or how they increase adoption of a program. The purpose of this study was to understand internal facilitation activities in implementing a national safe patient handling program from the perspective of facility coordinators who implemented the program.MethodsUsing a qualitative descriptive design, data were collected in five focus groups at two international Safe Patient Handling and Mobility Conferences. Participants were 38 facility coordinators implementing a safe patient handling program in the Department of Veterans Affairs medical centers throughout the United States. Data were analyzed using direct content analysis to gather descriptions of internal facilitation.ResultsThe internal facilitation process involved engaging multiple disciplines and levels of leadership for implementation. Fifty‐four facilitation activities were identified, including five activities not currently listed in an existing taxonomy. Key characteristics and skills of facilitators included persistence, credibility and clinical experience, and leadership and project management experience. Themes were mapped onto an existing framework and taxonomy of facilitation activities.Linking Evidence to ActionInternal facilitation is both an implementation intervention and a process involving a wide range of activities. The findings provide an understanding of what internal facilitators are doing to support practice changes and the characteristics and skills of internal facilitators that are likely to result in long‐term organizational change. Five recommendations for action address organizations, senior leaders, and internal facilitators.
Predictors of Health Status in Mothers of Premature Infants with Implications for Clinical Practice and Future Research
Authors: Wu Chia‐Yao , Hung Chich‐Hsiu , Chang Ying‐Ju 
Published: July 2015

ABSTRACTBackgroundPostpartum health research has focused primarily on full‐term mothers.AimsTo explore postpartum stress, depression, social support, health status, and predictors of health status in mothers of premature infants.MethodsThis study employed a cross‐sectional design. With convenience sampling, a total of 203 mothers of premature infants were recruited from two medical centers and four community teaching hospitals in southern Taiwan. The Hung Postpartum Stress Scale, Social Support Scale, Beck Depression Inventory, and Chinese Health Questionnaire were used to assess the mothers’ psychosocial features during the first 6 weeks postpartum.ResultsMothers’ health status differed significantly according to levels of postpartum stress and depression. The important health status predictors were age, education, postpartum stress, and depression level.DiscussionThe concerns and needs of mothers of premature infants differed from those of full‐term mothers during the first 6 weeks postpartum; premature infants’ health status was found to be a major perceived stressor for their mothers.Linking Evidence to ActionIn the process of caring for premature infants’ mothers, healthcare providers should provide individualized care to meet their needs, thus facilitating the reduction of postpartum stress and depression levels. During premature infants’ hospitalizations, healthcare providers should hold regular faculty meetings to provide postpartum women with relevant information about their infants’ health and how to best care for them. Future studies should explore postpartum stress, social support, depression, and health status each postpartum week, which could serve as a guide for nursing interventions.