bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analytical Models for Liquid Loading in Multifractured Horizontal Gas Wells
Authors: Shi Juntai , Sun Zheng , Li Xiangfang 
Published: August 2015

Summary
Liquid loading is a key issue in gas reservoirs with horizontal wells and multiple hydraulic fractures, especially for shale-gas reservoirs. Field results show that only 15–30% of the original fracturing fluid is recovered. Most liquid is trapped in the rock matrix near the fracture face and induced fractures. Water flowback from reservoir to wellbore and liquid loading from wellbore to surface are two main factors affecting the recovery of the original fracturing fluid. Significant efforts have been made to understand the effect of liquid loading on well performance, and some models have been proposed to describe the liquid loading. However, these models ignore the effect of liquid-drop size and its shape change with size. The falling liquid is nearly spherical in shape when its diameter is smaller than 2 mm, but when larger than 2 mm, it will change to be a half-hamburger in shape. Hence, ignoring the liquid-drop size and its shape change with size will lead to inaccurate calculations of the critical liquid-loading-flow rate.
In this study, we conduct several groups of experiments to examine the liquid-droplet-shape change with liquid-droplet size in a gas-flow wellbore with different inclined angles. Similar to the falling liquid in air, larger liquid droplets are half-hamburger in shape (like the top half of the bun, flat on bottom and round on top). On the basis of this phenomenon, we propose analytical models to describe the critical liquid loading in vertical, slanted, and horizontal wellbores by considering the size and shape of liquid drops. Also, we validate this model by use of field data from the Daniudi gas field, and apply the proposed model to evaluate the liquid-loading problem in the Marcellus shale. Results show that the ratio of the liquid-drop height/width is a strong function of the liquid-drop width. Both the maximum and minimum ratios are determined: The maximum is unity, representing the shape of a sphere; the minimum is 0.3765; and the liquid drop is unstable when the ratio is less than 0.3765. In addition, the liquid drop with the minimum ratio is most easily loaded and produced from the vertical wellbore of gas wells. The key coefficient of B in the model of critical liquid-loading-flow velocity—vg = B[σ(ρl–ρg)/ρg2]0.25—is a function of the width of the liquid drop. The range of B is quantified as from 1.54 to 2.5. In the slanted wellbore of gas wells, the critical liquid-loading gas-flow velocity is related to the angle β, the slant angle, and the width of the liquid droplet. In the horizontal wellbore of gas wells, the critical liquid-loading gas-flow velocity is a function of the width of the liquid droplet. The models proposed in this work can accurately calculate the critical liquid-loading-flow rate for multifractured horizontal gas wells. This study can provide critical insights into the understanding of the liquid flowback and its effect on well productivity in gas reservoirs.
Conjunctival TGF-B Level in Primary Augmented Trabeculectomy
Authors: Ng Guan Fook , Raihan Ishak Siti , Azhany Yaakub , Maraina Che Hussin Che , Banumathi K. Gurusamy , Liza-Sharmini Tajudin 
Published: August 2015

Purpose :
To compare the levels of conjunctival transforming growth factor beta (TGF-β) between glaucoma and control patients and to determine conjunctival TGF-β levels before and 3 months after augmented primary trabeculectomy.

Methods :
Patients with primary open angle glaucoma (POAG) or primary angle closure glaucoma (PACG) admitted for mitomycin (MMC) augmented primary trabeculectomy due to failure in achieving target pressure after maximum medical therapy were selected. Age-matched non-glaucoma patients were controls. Impression cytology of the conjunctiva was obtained twice from glaucoma patients (1 week before augmented primary trabeculectomy and 3 months after surgery) and once from controls. Conjunctival cells were tagged with an anti-TGF-β antibody and analyzed by flow cytometry.

Results :
Eighteen patients (11 POAG and 7 PACG patients) and 18 age-matched control patients were included. Conjunctival TGF-β levels were significantly different between glaucoma (35.21% ± 14.12%) and control patients (14.96% ± 6.34%) (p = 0.001). There was a significant reduction in conjunctival TGF-β levels after augmented trabeculectomy (23.0% ± 13.8%) (p < 0.001). A significantly greater reduction in conjunctival TGF-β levels (61.6% ± 17.9%) was associated with complete success of trabeculectomy at 3 months (83.3%) after surgical intervention (p = 0.029).

Conclusion :
The reduction of TGF-β on the conjunctival post primary augmented trabeculectomy may suggest TGF-β as potential predicting marker of short term trabeculectomy success. However, the result may be affected by site of impression, topical pressure lowering drugs and small sample size.
Trichoscopy Simplified
Authors: Elghblawi Ebtisam 
Published: August 2015

It has been a long while since skin surfaces and skin lesions have been examined by dermoscopy. However
examining the hair and the scalp was done again recently and gained attention and slight popularity by the practical tool,
namely trichoscopy, which can be called in a simplified way as a dermoscopy of the hair and the scalp. Trichoscopy is a
great tool to examine and asses an active scalp disease and hair and other signs can be specific for some scalp and hair
diseases. These signs include yellow dots, dystrophic hairs, cadaverized (black dots), white dots and exclamation mark
hairs.
Trichoscopy magnifies hair shafts at higher resolution to enable detailed examinations with measurements that a naked eye cannot distinguish nor see.
Trichoscope is considered recently the newest frontier for the diagnosis of hair and scalp disease.
Aim of this paper. The aim of this paper is to simplify and sum up the main trichoscopic readings and findings of hair and scalp disorders that are commonly encountered at clinic dermatology settings.
Rates of Diabetic Ketoacidosis: International Comparison With 49,859 Pediatric Patients With Type 1 Diabetes From England, Wales, the U.S., Austria, and Germany
Authors: Maahs David M. , Hermann Julia M. , Holman Naomi , Foster Nicole C. , Kapellen Thomas M. , Allgrove Jeremy , Schatz Desmond A. , Hofer Sabine E. , Campbell Fiona , Steigleder-Schweiger Claudia , Beck Roy W. , Warner Justin T. , Holl Reinhard W. 
Published: August 2015

OBJECTIVE
Diabetic ketoacidosis (DKA) in children and adolescents with established type 1 diabetes is a major problem with considerable morbidity, mortality, and associated costs to patients, families, and health care systems. We analyzed data from three multinational type 1 diabetes registries/audits with similarly advanced, yet differing, health care systems with an aim to identify factors associated with DKA admissions.

RESEARCH DESIGN AND METHODS
Data from 49,859 individuals &lt;18 years with type 1 diabetes duration ≥1 year from the Prospective Diabetes Follow-up Registry (DPV) initiative (n = 22,397, Austria and Germany), the National Paediatric Diabetes Audit (NPDA; n = 16,314, England and Wales), and the T1D Exchange (T1DX; n = 11,148, U.S.) were included. DKA was defined as ≥1 hospitalization for hyperglycemia with a pH &lt;7.3 during the prior year. Data were analyzed using multivariable logistic regression models.

RESULTS
The frequency of DKA was 5.0% in DPV, 6.4% in NPDA, and 7.1% in T1DX, with differences persisting after demographic adjustment (P &lt; 0.0001). In multivariable analyses, higher odds of DKA were found in females (odds ratio [OR] 1.23, 99% CI 1.10–1.37), ethnic minorities (OR 1.27, 99% CI 1.11–1.44), and HbA1c ≥7.5% (≥58 mmol/mol) (OR 2.54, 99% CI 2.09–3.09 for HbA1c from 7.5 to &lt;9% [58 to &lt;75 mmol/mol] and OR 8.74, 99% CI 7.18–10.63 for HbA1c ≥9.0% [≥75 mmol/mol]).

CONCLUSIONS
These multinational data demonstrate high rates of DKA in childhood type 1 diabetes across three registries/audits and five nations. Females, ethnic minorities, and HbA1c above target were all associated with an increased risk of DKA. Targeted DKA prevention programs could result in substantial health care cost reduction and reduced patient morbidity and mortality.
The diaphonic aspect of phonotactics
Authors: Bańczerowski Jerzy 
Published: August 2015

Abstract
The diaphonic aspect of phonotactics as a necessary counterpart of the isophonic aspect is being subjected to investigation. A ll assumptions and definitions are exemplified with P olish language material. Having recollected and relatively precisely explained phonological terms, indispensible for the subsequent inquiry, the distinction between diacrisis and diaphony is discussed, and several useful concepts such as the diaphonotacteme, diaphonic pair, diaphonic range, diaphonotactemic length etc. are introduced. N ext some fundamental phonotactological terms are defined to which, among others, the following belong: diaphonic load, diacritic range, the diatactophoneme, diaphonic dispersion, diacritic dispersion, types of diaphony and diacrisis. A lso some problems of diaphonic paradigm and diaphonic coding are considered. Finally, a phonotactological typology within the framework of comparative phnotactology of languages is postulated
Sonority effects in the production of fricative + sonorant clusters in polish
Authors: Castellví Joan , Szmidt Dorota T. 
Published: August 2015

Abstract
This paper presents the results of a phonetic study on the occurrence of transition elements in Polish fricative + nasal clusters. A n acoustic study was carried out using the CSL system, with simultaneous observation of the waveform, spectrograph, glottal waveform and glottal pulses. T he results reveal differences in glottal activity depending on place of articulation of the fricative and in its duration with respect to the extent of glottal vibration. Differences in the glottal activity pattern and the transition elements between the fricative and the nasal were also observed. In the fricative-nasal limit three phenomena were found: a voiceless interval, a voiced interval and the absence of any transition element. It was also observed that the occurrence and the characteristics of the transition interval depend on the place of articulation of the fricative
Duration and speed of speech events: A selection of methods
Authors: Gibbon Dafydd , Klessa Katarzyna , Bachan Jolanta 
Published: August 2015

Abstract
The study of speech timing, i.e. the duration and speed or tempo of speech events, has increased in importance over the past twenty years, in particular in connection with increased demands for accuracy, intelligibility and naturalness in speech technology, with applications in language teaching and testing, and with the study of speech timing patterns in language typology. H owever, the methods used in such studies are very diverse, and so far there is no accessible overview of these methods. Since the field is too broad for us to provide an exhaustive account, we have made two choices: first, to provide a framework of paradigmatic (classificatory), syntagmatic (compositional) and functional (discourse-oriented) dimensions for duration analysis; and second, to provide worked examples of a selection of methods associated primarily with these three dimensions. Some of the methods which are covered are established state-of-the-art approaches (e.g. the paradigmatic Classification and Regression Trees, CART , analysis), others are discussed in a critical light (e.g. so-called ‘rhythm metrics’). A set of syntagmatic approaches applies to the tokenisation and tree parsing of duration hierarchies, based on speech annotations, and a functional approach describes duration distributions with sociolinguistic variables. Several of the methods are supported by a new web-based software tool for analysing annotated speech data, the Time Group Analyser.
First and second language acquisition: Towards a reconcillation
Authors: Nau Nicole 
Published: August 2015

Abstract
For the past two decades, research on first language acquisition on the one side, and on second language acquisition and learning on the other have largely developed separately, probably as a reaction to the failure of earlier attempts to use the same methods or simply transfer insights gained in one of the fields to the other. T his article argues that a reconciliation may be fruitful, provided that different aspects which have often got blurred in the discussion are considered separately. These aspects include the assessment of multilingualism and monolingualism, the age factor and the definition of “first” and “second” language, the understanding of linguistic competence and of completeness of acquisition, different forms of acquisition and learning, and uniformity vs. individual differences in the process of language acquisition. By challenging some widely held views on characteristics of first language acquisition and its differences to second language learning, more fine-grained research questions are revealed, some of which have been addressed in recent studies on language acquisition and multilingualism
Factors influencing the pronunciation of adult speakers of a foreign language
Authors: Szalkowska-Kim Emilia 
Published: August 2015

Abstract
The present paper is an overview of selected investigations into acquisition of second language phonology (L2).1 It describes L2 phonology researchers’ attempts to determine the number, quantity, quality and roles of the factors which shape the pronunciation of L2 adult speakers, i.e. what is the influence of native language limitation, how the L2 phonology acquisition is governed by universal linguistic features, and whether adults use the same processes in acquiring the L2 that are used by children when they acquire their first language. This article will describe a number of longstanding phonetic and phonological projects whose aim was to discover patterns in the improvement of pronunciation in a second language (see research by Archibald, Broselow, Eckman, Flege, Hancin-Bhatt, Major and Weinberger, published in numerous compilations). It strives to explain the universal stages in the development of second language phonology. The main goal of the research is to assess the grammatical knowledge of the L2 learner, i.e. their competence in their interlanguage. The analyses show typological disproportions and universality of the strategies applied by the speakers in the target language. A few important hypotheses have been established (see below for their description), but it is important to note that most of the results verifying these hypotheses concern the acquisition of the English language, with a variable being the “input” languages of the speakers. Although this unilateral focus of the research projects reflects the expansion of the English language as the lingua franca of modern times, it might severely limit understanding of the important and interesting aspects of second language acquisition which structurally do not apply to that language, and are consequently overlooked.
The SVM Method As An Instrument For The Classification Of Vertical Displacements
Authors: Mrówczyńska Maria 
Published: August 2015

Abstract
The article presents the basic rules for constructing and training neural networks called the Support Vector Machine method as well as possible applications for this kind of network. SVM networks are mainly used for solving tasks of classifying linearly and non-linearly separable data and regression. However, in recent years more applications have been found for them. The networks also solve such problems as the recognition of signals and images as well as speech identification.
In this paper, non-linear SVM networks have been used for classifying linearly separable and non-separable data with a view to formulating a model of displacements of points in a measurement-control network. The points of the measurement-control network were placed on a civil engineering object located on expansive soil (linearly separable data) and represented a mining exploitation area (linearly non-separable data). The task of training SVM networks requires the use of quadratic programming in search of an optimum point of the Lagrangian function in relation to the parameters being optimised. In the case of linearly non-separable data, the SVM method makes it possible to find a hyperplane which classifies objects as correctly as possible, and at the same time is located possibly far away from concentrations typical of each class.
Determination Of Horizontal Geodetic Control Networks For Engineering Objects Using Optoelectronic Techniques
Authors: Ćmielewski Kazimierz , Kuchmister Janusz , Gołuch Piotr , Wilczyńska Izabela , Kowalski Krzysztof 
Published: August 2015

Abstract
The correctness of the geodetic service of an engineering object not seldom requires designing, alignment or renewing of geodetic situational control points. Building robots often cause that fixed situational control points are partly or completely inaccessible. For setting the position of these control points, there is worked out the methodology using the optoelectronic method. The prepared set of tools realizes the method’s assumptions and enables to determine the sides and control points based on the set of laser planes. In this article there is presented the innovative set of geodetic equipment for fixing horizontal control points. The presented set has been experimentally tested under laboratory conditions taking its functionality, operation range and applied accuracy into account. The measurement accuracy of the set of tools, resulting from identification of the energetic centres of laser planes’ edges, visualizing the sides of geodetic control networks, is within the range of ±0.02mm - ±0.05mm. There were also discussed exemplary versions of shapes and structures of horizontal geodetic control networks (regular and irregular), which are possible to be fixed with the use of the constructed set of tools.
Contactless Measurement Of Rectilinearity Of An Elongated Object Based On The Example A Crane Rail
Authors: Ćmielewski Kazimierz , Kuchmister Janusz , Gołuch Piotr , Bryś Henryk 
Published: August 2015

Abstract
The common aim of engineering surveys is to determine deviations from rectilinearity for elongated objects. We have developed a number of methods for measuring points that represent an elongated object. These are the constant straight (optical, laser, mechanical-string) method, the trigonometric method, geometric levelling method, photogrammetric methods and terrestrial laser scanning. When taking these measurements, it is crucial to have a direct access to the survey points of the measured object. Factors impeding the measurements include: adverse lighting conditions, vibration, dust, refractory effects, lack of direct access to the survey points, etc.
The authors have developed a measurement methodology and designed a measuring set for taking measurements that enable to determine the location of survey points on an elongated object.
The measurement is based on the constant straight method and the measuring set consists of the horizontal levelling staff and two laser pointers. The measuring set relies on the angular intersection (fixed angle) method. Intersection occurs when two laser beams meet. To determine the location of the survey point indicated by the mentioned laser beams, we used levelling staff readings taken with the surveying instrument that establishes the reference constant straight.
Experimental studies carried out in the laboratory and in the field helped to determine the accuracy of measurements taken with the designed measuring set (the accuracy was below ± 1 mm) and revealed that this accuracy is comparable to accuracies achieved with famous classical measurement methods.
Vector Products As A Tool For The Investigation Of The Isometric Transformation Of Objects
Authors: Grabowski Ryszard Józef 
Published: August 2015

Abstract
The identification of isometric displacements of studied objects with utilization of the vector product is the aim of the analysis conducted in this paper. Isometric transformations involve translation and rotation. The behaviour of distances between check points on the object in the first and second measurements is a necessary condition for the determination of such displacements. For every three check points about the measured coordinate, one can determine the vector orthogonal to the two neighbouring sides of the triangle that are treated as vectors, using the definition of the vector product in three-dimensional space. If vectors for these points in the first and second measurements are parallel to the studied object has not changed its position or experienced translation. If the termini of vectors formed from vector products treated as the vectors are orthogonal to certain axis, then the object has experienced rotation. The determination of planes symmetric to these vectors allows the axis of rotation of the object and the angle of rotation to be found. The changes of the value of the angle between the normal vectors obtained from the first and second measurements, by exclusion of the isometric transformation, are connected to the size of the changes of the coordinates of check points, that is, deformation of the object. This paper focuses mainly on the description of the procedure for determining the translation and rotation. The main attention was paid to the rotation, due to the new and unusual way in which it is determined. Mean errors of the determined parameters are often treated briefly, and this subject requires separate consideration.
Molecular cancer prevention: Current status and future directions
Authors: Maresso Karen Colbert , Tsai Kenneth Y. , Brown Powel H. , Szabo Eva , Lippman Scott , Hawk Ernest T. 
Published: August 2015

Answer questions and earn CME/CNEThe heterogeneity and complexity of advanced cancers strongly support the rationale for an enhanced focus on molecular prevention as a priority strategy to reduce the burden of cancer. Molecular prevention encompasses traditional chemopreventive agents as well as vaccinations and therapeutic approaches to cancer‐predisposing conditions. Despite challenges to the field, we now have refined insights into cancer etiology and early pathogenesis; successful risk assessment and new risk models; agents with broad preventive efficacy (eg, aspirin) in common chronic diseases, including cancer; and a successful track record of more than 10 agents approved by the US Food and Drug Administration for the treatment of precancerous lesions or cancer risk reduction. The development of molecular preventive agents does not differ significantly from the development of therapies for advanced cancers, yet it has unique challenges and special considerations given that it most often involves healthy or asymptomatic individuals. Agents, biomarkers, cohorts, overall design, and endpoints are key determinants of molecular preventive trials, as with therapeutic trials, although distinctions exist for each within the preventive setting. Progress in the development and evolution of molecular preventive agents has been steadier in some organ systems, such as breast and skin, than in others. In order for molecular prevention to be fully realized as an effective strategy, several challenges to the field must be addressed. Here, the authors provide a brief overview of the context for and special considerations of molecular prevention along with a discussion of the results from major randomized controlled trials. CA Cancer J Clin 2015;65:345–383. © 2015 American Cancer Society.