bluuebunny/crossref_metadata_2025_split huggingface dataset:
Two New Tetracyclic Triterpenoids and Other Constituents from Aster Ageratoides var. Oophyllus
Authors: Yan Fu‐Lin , Yao Su‐Mei , Zhou Yao 
Published: May 2015

AbstractTwo new tetracyclic triterpenoids shiona‐19(E),21‐dien‐3β‐ol (1), and shiona‐22(29)‐en‐3β,21‐diol (2), together with four known compounds shiona‐21‐en‐3β‐ol (3), friedelinol (4), β‐sitosterol (5), and (24R)‐stigmast‐7,22(E)‐dien‐3a‐ol (6) were isolated from Aster ageratoides var. oophyllus. The structures of two new compounds were established on the basis of IR, MS, 1H, 13C and 2D NMR spectroscopic methods.
Polymer‐Supported Hypervalent Iodine Reagent Mediated Synthesis of α‐Azidoketones
Authors: Wang Huey‐Min , Hou Rei‐Sheu , Wu Jian‐Long , Chen Ling‐Ching 
Published: May 2015

AbstractThe reaction of aryl ketones with sodium azide using polymer‐supported bis(trifluoroacetoxyiodo)‐benzene (PSBTI) in the presence of trifluoroacetic acid (TFA) to prepare α‐azidoketones in one‐pot conditions is reported.
Basic Alumina as an Efficient Catalyst for Preparation of Semicarbazones in Solvent Free Conditions
Authors: Kiasat Ali Reza , Kazemi Foad , Mehrjardi Mehdi Fallah 
Published: May 2015

AbstractAn efficient and simple procedure for conversion of different classes of aldehydes and ketones into the corresponding semicarbazones with semicarbazide hydrochloride using basic alumina is studied.
Synthesis of Deuterium Labeled Tryptamine Derivatives
Authors: Wang Yu‐Yun , Chen Chinpiao 
Published: May 2015

AbstractThe synthesis of deuterium labeled tryptamine derivatives, [2‐(1H‐indol‐3‐yl)‐[2H4]‐ethyl]‐dimethylamine (DMT), [2H10]‐diethyl‐[2‐(1H‐indol‐3‐yl)‐ethyl]‐amine (DET), [2‐(1H‐indol‐3‐yl)‐ethyl]‐[2H6]‐dipropyl‐amine (DPT) and [2H2]‐alpha‐methyltryptamine (AMT) is described. The isotopically labeled compounds are used as internal standards in gas chromatography‐mass spectrometry (GC‐MS) assays.
Physical Properties of 8‐Substituted 5,7‐Dichloro‐2‐Styrylquinolines as Potential Light Emitting Materials
Authors: Chen Grace Shiahuy , Talekar Rahul Subhash , Wong Ken‐Tsung , Chi Liang‐Chen , Chern Ji‐Wang 
Published: May 2015

AbstractDerivatives of 5,7‐dichloro‐2‐styrylquinoline (1), modified at position 8 of quinoline moiety with a methyl ether (4, DCSQM) or acetate (5, DCSQA), were synthesized and investigated. Both compounds exhibited high thermal stability (Td > 320 °C). The UV‐vis absorption of DCSQM and DCSQA varied only slightly in different solvents, whereas the emission spectra showed pronounced red shifts with increasing solvent polarity, suggesting the intramolecular charge transfer character of the emission state. Compounds 4 and 5 can emit lights from blue to green color in different solvents. The solvent polarity dependent electronic transitions are attributed to efficient intramolecular charge transfer (ICT) processes, in which the HOMOs and LUMOs are localized on the styrene‐based ring and the quinoline‐based moiety, respectively. The quinoline‐based LUMO provides compelling evidence that the first reduction site occurs on the electron‐deficient quinoline moiety.
Microwave Dielectric Behaviour of 1,2‐Propanediol‐Water Mixture Studied Using Time Domain Reflectometry Technique
Authors: Chavan Satyajit , Kumbharkhane Ashok , Mehrotra Suresh 
Published: May 2015

AbstractThe dielectric behaviour of 1,2‐propanediol was investigated to understand the effect of the hydroxyl group on the dielectric parameters. The measurement of permittivity ϵî and ϵîî of 1,2‐propanediol was carried out in the frequency range 10 MHz to 20 GHz at 25 °C temperature. Static permittivity and dielectric relaxation time are extracted from a 1,2‐propanediol‐water mixture using the bilinear calibration method and non‐linear least squares fit method. Calculated Kirkwood correlation factor contains information regarding solute‐solvent interaction. The hydrogen bonded model suggested by Luzar is applied to determine the molecular parameters. The excess dielectric parameters and Bruggeman factor show the systematic change in the dielectric parameter of the system with change in concentration.
A New Silver(I) Potentiometric Sensor Based on a Calix[4]arene Substituted at the Narrow Rim by Amide/Phosphoryl Groups
Authors: Parsa Majid , Yaftian Mohammad Reza , Matt Dominique 
Published: May 2015

AbstractA coated‐wire type silver ion‐selective electrode has been constructed using a modified p‐tert‐butyl‐calix[4]arene by amide‐phosphoryl groups, named 5, 11, 17, 23‐tetra‐tert‐butyl‐25, 27‐bis(diethylcarbamoylmethoxy)‐26,28‐bis(diphenylphosphinoylmethoxy)calix[4]arene (Calix), as neutral carrier. A plasticized PVC membrane containing 30% PVC, 60% ortho‐nitrophenyloctylether (NPOE), 2% sodium tetraphenylborate (NaTPB) and 8% “Calix” was coated on a graphite rod. The prepared electrode exhibited a linear Nernstian response over the range 1 × 10−6 to 1 × 10−2 M with a slope 58.4 (±0.2) mV per decade change and a detection limit of 6.3 × 10−7 M. The working pH range of the sensor is 4‐6.7. It is found that the dynamic response time of the electrode to achieve a steady potential was very fast (∼11 s). The selectivity of the sensor relative to NH4+, Li+, Na+, K+, Ca2+, Sr2+, Ba2+, Mn2+, Pb2+, Co2+, Ni2+, Cu2+, Zn2+, Cd2+, Fe3+, La3+, Sm3+ and Th4+ was examined. The prepared electrode exhibits adequate stability with good reproducibility (57.6 ± 0.5 mV per decade change for 10 weeks). It was successfully used as an indicator electrode in potentiometric titration of silver ions with standard solution of EDTA. The sensor was also used for silver ion measurements in various synthetic samples.
A Lead‐Selective Membrane Electrode Based Upon a Phosphorylated Hexahomotrioxacalix[3]Arene
Authors: Yaftian Mohammad Reza , Parinejad Massoumeh , Matt Dominique 
Published: May 2015

AbstractSolvent extraction of a mixture of PbII, MnII, FeIII, CoII, NiII and CdII in aqueous perchlorate medium by a phosphorylated hexahomotrioxacalix[3]arene (calix‐3) in dichloromethane shows a significant selectivity towards lead ions. The ligand can also be incorporated into a membrane to provide a new lead ion‐selective electrode (PbII‐ISE). A plasticized PVC membrane containing 30% PVC, 53.5% ortho‐nitrophenyloctylether (NPOE), 4.5% sodium tetraphenylborate (NaTPB) and 12% ionophore was directly coated on a graphite rod. This sensor gave a good Nernstian response of 29.7 ± 0.7 mV decade−1 over a concentration range of 1 × 10−8 – 1 × 10−4 M of lead ions, independent of pH in the range 3‐7, with a detection limit of 0.4 × 10−8 M. The dynamic response time of the electrode to achieve a steady potential was very fast and found to be less than 7 s. The selectivity relative to Ag+, NH4+, Li+, Na+, K+, Ca2+, Sr2+, Ba2+, Mn2+, Fe2+, Co2+, Ni2+, Cu2+, Zn2+, Cd2+, Fe3+, La3+, Sm3+, Dy3+, Er3+, Y3+ and Th4+ was examined. The electrode exhibits adequate stability with good reproducibility (with a slope of 29.6 ± 1.5 mV for 8 weeks). The characteristics of the sensor are compared with those of a tetraphosphorylated calix[4]arene (calix‐4) based PbII‐ISE, reported recently. The electrode was successfully used as an indicator electrode for a potentiometric titration of a lead solution using a standard solution of EDTA. The applicability of the sensor for lead ion measurements in various synthetic samples was also investigated.
Triterpenoids and other Constituents from Euphorbia Humifusa
Authors: Pei Ying‐Ge , Wu Quan‐Xiang , Shi Yan‐Ping 
Published: May 2015

AbstractA novel lupane‐type triterpenoid, 3,4‐seco‐lupa‐4(23), 20(29)‐dien‐24‐hydroxy‐3‐oic acid (1) and a new cycloartane‐type triterpenoid, 23(E)‐cycloart‐23‐en‐25‐ethoxy‐3β‐ol (7), as well as eighteen known compounds, were isolated from the hot ethanol extract of the whole plant of Euphorbia humifusa Willd. The new structures were characterized by means of spectroscopic methods including 1D, 2D NMR and HRESIMS, and the known ones were established on the basis of comparing their NMR data with those of the corresponding compounds in the literature. In addition, cytotoxicity against selected cancer cell human gastric carcinoma (SGC‐7901) of compounds 1,3,4,6 were measured in vitro.
Diastereoselective Three Component Reaction of N‐Glyoxyloyl Camphorpyrazolidinone, Amine and Allyltributylstannane: Facile Synthesis of Homoallylic Amines
Authors: Chang Chih‐Liang , Chen Kwun‐Min 
Published: May 2015

AbstractDiastereoselective allylation of imine derived from N‐glyoxyloyl camphorpyrazolidinone and amines was treated with allyltributylstannane in the presence of triflic acid. The corresponding optically enriched homoallylic amines were obtained in reasonable to high material yields and with practical levels of stereoselectivity in 10 min at ambient temperature.
Laser Induced Transient Structures in a 150 nm Gold Crystal
Authors: Chen Jie , Zhang Hua , Tomov Ivan V. , Rentzepis Peter M. 
Published: May 2015

AbstractThe evolution of transient structures induced in gold crystals by irradiation with 400 nm, 100 fs laser pulses has been measured by means of time resolved x‐ray diffraction. The data show that the photon/electron interaction generates a hot electron wave on a 150 nm Au crystal, which is responsible for a “blast force” that generates an intense shock wave that alters the lattice structure as it propagates, with sound velocity, through the bulk of the crystal. This mechanical force is developed within 1‐2 ps after the laser pulse interacts with the gold surface electrons. Other major effects that have contributed to the strain in the lattice have also been evaluated.
Alumina Supported 12‐Tungstophosphoric Acid as an Efficient and Reusable Catalyst for Synthesis of 1,5‐Benzodiazepines
Authors: Abdollahi‐Alibeik Mohammad , Zaghaghi Zahra , Mohammadpoor‐Baltork Iraj 
Published: May 2015

AbstractAlumina supported 12‐tungstophosphoric acid catalyzes efficiently the reaction of o‐phenylenediamine with ketones under solvent‐free condition to afford the corresponding 1,5‐benzodiazepines in good to excellent yields. The catalyst can be recovered and reused.
Study on Chromium‐Containing Aluminophosphate CrAPO‐5 via Density Functional Theory
Authors: Cheng Hsiu‐Yao , Chang Jung‐Tzu 
Published: May 2015

AbstractVarious structures of CrAPO‐5 clusters are studied via density functional B3LYP exchange‐correlation method. The optimized structures are compared with data from X‐ray absorption. Their total energies and atomic net charges are also analyzed. Results indicate that the substitution of the aluminum site of an AFI framework by chromium is in general not feasible. The chromium ion is more likely docked in between two neighboring 12‐membered rings of the framework of AFI. To further verify our claim, the excitation energies of the representative chromium structures of CrAPO‐5 clusters are calculated via the TDDFT method. The results for excitation energies further support that Cr3+ is not incorporated into the framework.
Determination of Point of Zero Charge of Tunisian Kaolinites by Potentiometric and Mass Titration Methods
Authors: Kriaa A. , Hamdi N. , Srasra E. 
Published: May 2015

AbstractThis paper deals with determining points of zero charge of natural and Na+‐saturated mineral kaolinites using two methods: (1) acid‐base potentiometric titration was employed to obtain the adsorption of H+ and OH− on amphoteric surfaces in solutions of varying ionic strengths in order to determinate graphically the point of zero net proton charge (PZNPC) defined equally as point of zero salt effect (PZSE); (2) mass titration curve at different electrolyte concentrations in order to estimate PZNPCs by interpolation and to compare with those determined by potentiometric titrations. The two methods involved points of zero charge approximately similar for the two kaolinites between 6.5‐7.8, comparable to those reported previously and were in the range expected for these clay minerals. The comparison of potentiometric surface titration curves obtained at 25 °C and those published in the literature reveals significant discrepancies both in the shape and in the pH of PZNPCs values.
Solid Phase Extraction of Neutral Analytes through Silica Gel Coated with Layers of Au Nanoparticles Self‐Assembled with Alkanethiols
Authors: Liu Fu‐Ken 
Published: May 2015

AbstractIn this study, we used Au nanoparticle (NP)‐coated silica gel as a solid phase extraction sorbent for the preconcentration of neutral analytes (steroid drugs). The sorbent was fabricated using two alkanethiol self‐assembly processes: one to deposit the Au NPs onto a 3‐aminopropyltrimethoxysilane‐modified silica gel and the other to functionalize the surfaces of the Au NPs. A large volume of the steroid solution was passed through the silica gel to facilitate adsorption mediated by hydrophobic interactions between the steroids and the hydrophobic moieties on the silica gel surface. Extraction of the steroids was accomplished by flushing the silica gel with a low‐polarity solvent. In this preliminary study, we found that the particle size of the silica gel and the number of layers of Au NPs coated on the silica gel both affected the preconcentration performance for the steroids. When using six layers of Au NPs coated on 5–20‐μm silica gel, the detection limits for steroids were below 80 ng L−1; the preconcentration efficiency was over 170‐fold higher than that of the original steroid solution. Our findings provide further evidence that nanotechnology has much to benefit analytical science.
The Nitrogen‐Assisted Triphenylphosphine Displacement of Methylpyridine Ligand in Palladium(II) Complex: Crystal Structures of [Pd(PPh3)2{η1‐C5H3N(CH3)}(Br)] and [Pd(PPh3)Br]2{μ,η2‐C5H3N(CH3)}2
Authors: Yih Kuang‐Hway , Lee Gene‐Hsiang 
Published: May 2015

AbstractTreatment of Pd(PPh3)4 with 2‐bromo‐4‐methylpyridine, C5H3N(CH3)Br, in dichloromethane at −20 °C causes the oxidative addition reaction to produce the palladium complex [Pd(PPh3)2 {η1‐C5H3N(CH3)}(Br)], 2, by substituting two triphenylphosphine ligands. In a dichloromethane solution of complex 2 at room temperature for 3 h, it undergoes displacement of the triphenylphosphine ligand to form the dipalladium complex [Pd(PPh3)Br]2{μ,η2‐C5H3N(CH3)}2, 3, in which the two 4‐methylpyridine ligands coordinated through carbon to one metal center and bridging the other metal through the nitrogen atom. Complexes 2 and 3 are characterized by X‐ray diffraction analyses.
Synthesis of Some Newer Analogues of 4‐Hydroxyphenyl Acetic Acid as Potent Anti‐Inflammatory Agents
Authors: Amir Mohammad , Javed Sadique A. , Kumar Harish 
Published: May 2015

AbstractA series of 1,3,4‐oxadiazole and 1,2,4‐triazole derivatives of 4‐hydroxyphenyl acetic acid have been synthesized and evaluated for their anti‐inflammatory activity by carrageenan induced rat paw edema method. The compounds, which showed good anti‐inflammatory activity, were screened for their ulcerogenic and lipid peroxidation activities.
Enamination of β‐Dicarbonyl Compounds with Amines
Authors: Khodaei M. M. , Khosropour A. R. , Cardel C. 
Published: May 2015

AbstractEnamination of a wide variety of primary amines was successfully described with excellent chemo‐selectivity in the presence of catalytic amounts of β‐cyclodextrin in water under mild conditions. Aliphatic amines also reacted efficiently to produce the corresponding enaminones.
A Novel, Simple and Efficient Synthesis of 3‐Amino‐Benzo[d]imidazo[2,1‐b]Thiazole Derivatives via a Multicomponent Procedure
Authors: Sun Chang , Ji Shun‐Jun , Liu Yu 
Published: May 2015

Abstract3‐Amino‐benzo[d]imidazo[2,1‐b]thiazoles were synthesized in moderate to good yields in the presence of NH4Cl via a one pot procedure. All the products were characterized by 1H NMR, IR, HRMS.
Molecular Simulation of HER2/neu Degradation by Inhibiting HSP90
Authors: Chen Calvin Yu‐Chian , Chen Guan‐Wen , Chen Winston Yu‐Chen 
Published: May 2015

AbstractSeveral flavonoids were investigated for the degradation of the HER2/neu (ErbB‐2), while the mechanism is still unknown. A hypothesis was generated here that the inhibition of HER2/neu expression was blocked by heat shock protein 90α (HSP90α) through 1‐benzyl‐3‐(5‐hydroxymethyl‐2‐furyl)indazole (YC‐1) derivatives and flavonoids. In order to ensure the accuracy of the simulated protein structure, the RMSD value between the ligand in crystal structure from PDB and the ligand docking into HSP90α was 1.13 Å. By molecular simulation, the flavonoids and YC‐1 derivatives were employed to dock into HSP90α. The results showed a good correlation between the evaluation scores of the flavonoids/HSP90α complexes and the IC50 of flavonoids‐induced degradation of HER2/neu. The YC‐1 derivatives showed higher score values and lower interaction energies on average. Especially, the CLC107 got the highest rank in Potential of Mean Force (PMF) and Dock Score. Luteolin showed the highest dock score and quercetin had the lowest interaction energy of all flavonoid derivatives. This study investigated that the YC‐1 derivatives and the flavonoids may be potent inhibitors for HSP90α in antitumor strategies.
Effect of Aging on the Physico Chemical Properties of Glass Fiber under Different Environmental Conditions
Authors: Khan Muzzaffar , Akhtar Gul , Saeed Arshad , Ullah Najeeb , Ahmad Imtiaz 
Published: May 2015

AbstractGlass fibers were characterized for physical and chemical changes before and after subjecting to aging under different environmental conditions. The conditions selected were: low temperature, outdoor atmosphere, indoor atmosphere, chemical environment, 95% humidity & water soaking treatment. The results show that glass fiber is a good candidate to resist sunlight, corrosive atmosphere, low temperature and shady atmosphere. The influence of prolonged time exposure to water caused a detrimental effect on the properties of the glass fiber. Hence, prolonged exposure to water should be avoided for the integrity of the glass fiber under study.
Simultaneous Kinetic Determination of Phosphate and Silicate by Spectrophotometric H‐Point Standard Addition Method
Authors: Nekoei Mehdi , Mohammadhosseini Majid , Zarei Kobra 
Published: May 2015

AbstractThe H‐point standard addition method (HPSAM), based on spectrophotometric measurements for simultaneous determination of phosphate and silicate, has been established. The method is based on the difference between their reactions rates with molybdenum in the presence of ascorbic acid. The results revealed that phosphate and silicate could be determined simultaneously with the concentration ratios of phosphate to silicate varying from 1:10 to 12:1 in the binary mixtures. The effects of chelating agent nature, time, interferents and experimental variables are also investigated. Under working conditions, the proposed method was successfully applied to the simultaneous determination of phosphate and silicate in synthetic detergents.
Preconcentration Ultra Trace of Cd(II) in Water Samples Using Dispersive Liquid‐Liquid Microextraction with Salen(N,N′‐Bis(Salicylidene)‐Ethylenediamine) and Determination Graphite Furnace Atomic Absorption Spectrometry
Authors: Moghimi Ali 
Published: May 2015

AbstractDispersive liquid–liquid microextraction (DLLME) technique was successfully used as a sample preparation method for graphite furnace atomic absorption spectrometry (GF AAS). In this extraction method, 500 μL methanol (disperser solvent) containing 34 μL carbon tetrachloride (extraction solvent) and 0.00010 g Salen(N,N′‐bis(salicylidene)ethylenediamine) (chelating agent) was rapidly injected by syringe into the water sample containing cadmium ions (interest analyte). Thereby, a cloudy solution formed. The cloudy state resulted from the formation of fine droplets of carbon tetrachloride, which have been dispersed, in bulk aqueous sample. At this stage, cadmium reacts with Salen(N,N′‐bis(salicylidene)‐ethylenediamine), and therefore, hydrophobic complex forms which is extracted into the fine droplets of carbon tetrachloride. After centrifugation (2 min at 5000 rpm), these droplets were sedimented at the bottom of the conical test tube (25 ± 1 μL). Then a 20 μL of sedimented phase containing enriched analyte was determined by GF AAS. Some effective parameters on extraction and complex formation, such as extraction and disperser solvent type and their volume, extraction time, salt effect, pH and concentration of the chelating agent have been optimized. Under the optimum conditions, the enrichment factor 122 was obtained from only 5.00 mL of water sample. The calibration graph was linear in the range of 2‐21 ng L−1 with a detection limit of 0.5 ng L−1. The relative standard deviation (R.S.D.s) for ten replicate measurements of 20 ng L−1 of cadmium was 2.9%. The relative recoveries of cadmium in tap, sea and rain water samples at a spiking level of 5 and 10 ng L−1 are 99, 94, 97 and 96%, respectively. The characteristics of the proposed method have been compared with cloud point extraction (CPE), on‐line liquid‐liquid extraction, single drop microextraction (SDME), on‐line solid phase extraction (SPE) and co‐precipitation based on bibliographic data. Therefore, DLLME combined with GF AAS is a very simple, rapid and sensitive method, which requires low volume of sample (5.00 mL).
The Synthesis of N‐Glycosyl‐N′‐Pyrazolylmethylene Aminothioureas under a 4Å Molecular Sieve
Authors: Zhao Yan‐Wu , Cao Ling‐Hua 
Published: May 2015

AbstractA series of novel N‐glycosyl‐N′‐pyrazolylmethylene aminothioureas (4a‐4e, 5a‐5e) were synthesized from N‐glycosyl‐N′‐aminothioureas (2a‐2d) and 4‐formylpyrazole (3a‐3e). Activated 4Å molecular sieves were adopted for dehydrated reagent to improve the reaction rate and yield. The structures of the new compounds were identified on the basis of IR, 1H NMR and MS spectra. Simultaneously, the compounds were detected by fluorescence spectrophotometer and had preferable fluorescence activity, so they can be selected as a kind of novel fluorescence labeled derivative of sugar.
Selective 1,4‐Reduction of Chalcones with Zn/NH4Cl/C2H5OH/H2O
Authors: Li Jian‐Ping , Zhang Yong‐Xia , Ji Yan 
Published: May 2015

AbstractIn this paper, the Zn/NH4Cl/C2H5OH/H2O system was applied for the selective 1,4‐reduction of chalcones under mild conditions with high selectivity. The merit lies in inexpensive reagent, simple operation and environmental friendliness. The structures of the products were characterized by IR, 1HNMR, MS spectra and elemental analysis. A possible mechanism is also suggested.
Acyclic Diterpene‐γ‐Lactones and Flavonoid from Salix Cheilophila Omitted
Authors: Shen Tong , Tian Yong‐Qiang , Liu Wu‐Xia , Zheng Shang‐Zhen 
Published: May 2015

AbstractThree new phytane‐type diterpene‐γ‐lactone shaliuin I (2), shaliuin II (3) and shaliuin III (4) were isolated along with thirteen known compounds from twigs of Salix cheilophila omitted (Chinese name “Shaliu”, Salicaceae). The structures of three new compounds have been established on the basis of spectroscopic methods and 2D NMR techniques.
Novel Route to (+)‐Pinitol Intermediate via a Strategy Derived from Diazotization of O‐Isopropylidene‐Protected 4‐Amino‐2‐Cyclohexen‐1‐ol
Authors: Lin Kuo‐Wei , Wang Ying‐Chuan , Yan Tu‐Hsin 
Published: May 2015

AbstractA concise preparation of the enantiopure 1,2‐(isopropylidenedioxy)‐3,4‐epoxy‐5‐cyclohexene 2b, which is an important building block for (+)‐pinitol synthesis, evolved by combining the asymmetric cycloaddition of isopropylidenedioxy)cyclohexadiene to chiral chloronitroso with an internal substitution of an amino alcohol to create vinyl epoxide.
Efficient Synthesis of 4,5‐Disubstituted‐3‐Toluenesulfonyl Glutarimides. Application to the Formal Synthesis of Mappicine Ketone
Authors: Wang Yung‐Sheng , Chang Nein‐Chen , Lin Ching‐Han , Tai Huo‐Mu 
Published: May 2015

AbstractVarious 4,5‐disubstituted‐3‐sulfonyl glutarimides 3 were synthesized from α‐sulfonyl acetamide 1 and ethyl α,β‐disubstituted acrylate esters 2 via stepwise facile [3+3] annulation in moderate yield. The synthesis of pyridin‐2‐one 9, a key intermediate for mappicine ketone (4) synthesis, was also reported.