bluuebunny/crossref_metadata_2025_split huggingface dataset:
ETV6 Molecular Heterogeneity in Salivary Secretory Carcinoma: A Case Series Report and Literature Review
Authors: Mahomed Farzana , de Bruin Jana , Ngwenya Sizakele , Masango Zinhle , Hodkinson Katherine 
Published: August 2024

Abstract
Background
ETV6 gene rearrangement is the molecular hallmark of secretory carcinoma (SC), however; the nature, frequency, and clinical implications of atypical ETV6 signal patterns by fluorescence in situ hybridization (FISH) has not yet been systematically evaluated in salivary gland neoplasms.

Methods
The clinical, histopathologic, immunohistochemical and molecular features of seven salivary SCs, including four cases with atypical ETV6 FISH patterns, were retrospectively analyzed along with a critical appraisal of the literature on unbalanced ETV6 break-apart in SCs.

Results
The patients were four males and three females (31–70 years-old). Five presented with a painless neck mass and two patients with recurrent disease had a history of a previously diagnosed acinic cell carcinoma of the buccal mucosa. Histologically, there were varied combinations of microcystic, papillary, tubular, and solid patterns. All tumors were diffusely positive for S100 and/or SOX10, while 2 cases also showed luminal DOG1 staining. Rearrangement of the ETV6 locus was confirmed in 5/7 cases, of which 3 cases showed classic break-apart signals, 1 case further demonstrated duplication of the ETV6 5`end and the other loss of one copy of ETV6. Two cases harbored ETV6 deletion without rearrangement. Two of the 4 cases with atypical ETV6 FISH patterns represented recurrent tumors, one with widespread skeletal muscle involvement, bone and lymphovascular invasion. Surgical treatment resulted in gross-total resection in all 7 cases, with a median follow up of 9.5 months post-surgery for primary (n = 3) and recurrent disease (n = 1).

Conclusion
Duplication of the distal/telomeric ETV6 probe represented the most common (26/40; 65%) variant ETV6 break-apart FISH pattern in salivary SC reported in the literature and appears indicative of an aggressive clinical course.
Lectin from edible seaweed Meristotheca papulosa exhibits a high digestion-resistant property
Authors: Buendia Kathleen Kay , Kameda-Migita Nana , Teruya Hideyuki , Hori Kanji , Hirayama Makoto 
Published: August 2024

AbstractThe physiological impacts of polysaccharides and lipids in seaweed on human health are becoming clearer, but the behavior of the protein components, especially lectins, after ingestion remains poorly understood. In this study, we examined the resistance of edible red algae-derived lectins to digestive enzymes. We found that a lectin extracted from Meristotheca papulosa (MPL-1), belonging to the Jacalin-related lectin family, was relatively stable when subjected to both peptic and tryptic digestion and retained its hemagglutination activity after 24 h of digestion. The activity of MPL-1 was also maintained without a large change for 24 h following exposure to enzymes such as papain, Actinase E, and proteinase K, suggesting that MPL-1 possesses a strong resistant property against proteolytic digestion. We examined the anti-proliferation activity of the MPL fraction from the algal body against HT-29, a human colon cancer-derived cell line, and found that it showed a strong inhibitory activity with a half-maximal inhibitory concentration of 4.5 μg/mL. This activity was nullified in the presence of yeast mannan, an inhibitory sugar compound of lectin, demonstrating that MPL expressed its activity through binding to the glycan moieties on HT-29. This study indicates that this proteinase-resistant lectin could play a vital role after ingestion and is expected to have an inhibitory effect against colorectal cancer.
Evaluation of genetic diversity using simple sequence repeat markers and analysis of cross compatibility in hydrangeas
Authors: Bak SeongHwa , Han Tae-Ho 
Published: August 2024

AbstractHydrangeas with large inflorescences are widely used as cut flowers and in floral arrangements. However, the genetic diversity of commercially grown hydrangeas has been limited owing to the breeding focus on popular species. Therefore, this study was conducted to suggest interspecific breeding strategies for expanding the genetic diversity in Hydrangea L. by evaluating genetic diversity in the seven main species collected in Korea and analyzing cross compatibility via intra- and interspecific hybridization. Interspecific diversity evaluation using simple sequence repeat markers resulted in the segregation of 35 varieties accounting for seven species into five groups as follows: (1) Hydrangea paniculate group, (2) Hydrangea arborescnes group, (3) Hydrangea anomala and Hydrangea aspera group, (4) Hydrangea quercifolia group, and (5) Hydrangea macrophylla and Hydrangea serrata group. Cross compatibility was confirmed via intra- and interspecific crossing, and hybrids were obtained in 18 crossing combinations. Intraspecific hybrids tend to be easy to obtain, but interspecific hybrids are difficult to obtain due to a variety of factors. While most of the interspecific hybrids were obtained using ovule culture, the crossing between H. macrophylla and H. serrata created hybrids from seed sowing, indicating that H. serrata is a subspecies of H. macrophylla. Bilateral and unilateral incompatibilities were observed across the obtained hybrids. Particularly, weak bilateral compatibility was observed between H. serrata and H.paniculata. Accordingly, it was proposed that hybrids between H. macrophylla and H. serrata can be successfully used as parental materials in crossing with H. paniculata to improve cold tolerance. In addition, cross compatibility was improved in interspecific crossing using H. macrophylla and H. arborescens as maternal plants. It is anticipated that these finding will help improve the genetic diversity in commercial hydrangeas.
Accelerating Visual Anticipation in Sport Through Temporal Occlusion Training: A Meta-Analysis
Authors: Müller Sean , Morris-Binelli Khaya , Hambrick David Z. , Macnamara Brooke N. 
Published: August 2024

Abstract
Background
The video-based temporal occlusion paradigm has been consistently used in visual anticipation sport research.

Objective
This meta-analysis investigated the magnitude to which video-based temporal occlusion training could improve anticipation skill with transfer to representative laboratory and field tasks.

Methods
As there are considerably fewer anticipation training than performance studies, the meta-analysis included 12 intervention studies with 25 effect sizes where video simulation and/or field-based tests were used. The Downs and Black checklist adapted for sports science research was used to assess methodological quality of the included studies. Decision time and accuracy of anticipation were the outcome measures because both are relevant to sports skills. The changes in these measures between experimental and control groups from baseline to the transfer test context were used to calculate the magnitude of the training effect.

Results
Findings revealed a significant training effect, including a large meta-analytic effect size, and no difference in training benefit across video and field-based transfer tests. Publication bias analyses were inconclusive, likely due to the small number of available studies.

Conclusions
These findings are evidence that the temporal occlusion paradigm is an effective method to improve visual anticipation skill across representative perceptual and perceptual-motor transfer tests. The theoretical implication based upon the two-stage model of visual anticipation is that temporal occlusion training can improve use of early information for body positioning by the performer, which could in turn lead to improved execution of the skill goal.
Testing for Measurement Invariance (MI): Do the Structures of Microaggression, Discrimination, and Resilience Among Black Women Living with HIV Remain the Same Across Time?
Authors: Liu Jingxin , Feaster Daniel J. , Shahid Naysha , Lazarus Kimberly , Boga Devina J. , Willie Peyton , Juste Reyanna St. , Silva Maria Fernanda , Adeojo Layomi , Wright Mya , Reid Rachelle , Gonzalez Stephanie , Madhu Aarti , Warman Chelsie , Bolden Roxana , Pan Yue , Nelson C. Mindy , Hlaing WayWay , Rodriguez Allan , Alcaide Maria L. , Ironson Gail , Safren Steven , Wright Ian , Dale Sannisha K. 
Published: August 2024

AbstractAssessing measurement invariance and the interplay of discrimination, microaggressions, and resilience among Black women living with HIV (BWLWH) across time utilizing latent class and repeated measure analysis may provide novel insights. A total of 151 BWLWH in a southeastern U.S. city completed surveys focused on multiple forms of microaggressions and discrimination (race, gender, sexual orientation, or HIV-related) and resilience factors (social support, self-efficacy, post-traumatic growth) at baseline, 3 months, and 6 months. To capture the psychosocial domains of discrimination, microaggressions, and resilience, three latent factors were developed and measured across three time points. Latent class analysis was also conducted to identify and compare meaningful subgroups based on varying levels of discrimination, microaggressions, and resilience reported. Three latent classes were created. MI testing suggested that measurement invariance was partially met (established metric invariance and scalar invariance), and it is possible to compare factor means of discrimination, microaggressions, and resilience across time. Latent factor mean scores of microaggressions and discrimination decreased after 3 and 6 months and increased for resilience after 6 months and varied over time across the three latent classes identified. The subgroup with the lowest level of discrimination and microaggressions and the highest level of resilience reported at baseline, experienced increases in resilience after months 3 and 6. Clinical interventions, research, and policies aimed at promoting resilience and reducing structural and social barriers linked to racism, sexism, HIV stigma, and classism are needed to improve the health and well-being of BWLWH.
Optimization of malted cowpea compositions and extrusion parameters for best quality Ethiopian emmer wheat-based snack food
Authors: Teferi Desye Alemu , Satheesh Neela , Kassa Messenbet Geremew , Belachew Mikru Tesfa 
Published: August 2024

AbstractChildhood malnutrition is a major concern in developing countries, particularly in Ethiopia. This study aims to address this problem by assessing the nutritional properties of snacks made from locally available raw materials. The study used a twin-screw extruder machine to study the effects of different processing conditions (barrel temperatures, feed moisture content, and cowpea/emmer wheat blending ratio) on the nutritional properties of extruded products. The results showed a highly significant effect of these processing variables on the nutritional properties of snacks. Increasing cowpea in the blend boosted the protein and fiber content of the snack products. Increasing the barrel temperature from 80 to 120 °C notably decreased the protein and fat levels in the snack. The optimization of the combined interactive effects on an extruded snack made from 19.83% cowpea and 80.17% emmer wheat, cooked at 120 °C barrel temperature with 22.04% feed moisture content, produced acceptable extruded snack items. The products developed with optimized parameters contained 16.68%, 1.55%, 2.50%, 70.95%, and 364.43 kcal/g for protein, fat, fiber, carbohydrate, and gross energy, respectively. The study concludes that blending Emmer wheat and cowpea in extruded snacks can provide high protein and gross energy. This suggests a locally viable solution for addressing protein-energy malnutrition in developing regions, particularly Ethiopia.
Super-Resolution Virtual Scene Rendering Technology Based on Generalized Huber-MRF Image Modeling
Authors: Mao Dong , Rao Hanyu , Chen Zuge , Wang Jiaqi , Zhao Shuai , Wang Yidan 
Published: August 2024

AbstractThe traditional rendering technology creates virtual scenes with insufficient fidelity, which are quite different from real scenes. To address this issue, a super-resolution virtual scene rendering technology based on generalized Huber-MRF image modeling has been studied. This study preprocesses the original image through three steps: graying, filtering, and enhancement. The generalized Huber-MRF is employed for super-resolution image restoration to enhance image clarity. Corner features are extracted from the super-resolution image, and the Delaunay triangular grid method is used to construct the image's 3D model. Texture and lighting conditions of the virtual scene are then set through texture mapping, shadow rendering, and other technologies to achieve realistic scene effects. The results indicate that, when applied, the research technology yields a relatively small chamfer distance in virtual scene modeling, suggesting that the design method preserves the details and shape information of the original image, reducing the difference between the virtual scene and the real scene and increasing the fidelity of the virtual scene. Furthermore, this method achieves maximum PSNR and SSIM values of 17.54 and 0.978, respectively, with an image preprocessing time of only 1.21 s and a CPU utilization rate of only 35.5%. This method demonstrates excellent performance across multiple aspects.
The middle technology trap: China in a comparative perspective
Authors: Zheng Yongnian 
Published: August 2024

AbstractThis article examines the concept of the "middle technology trap" as a critical challenge for China in transitioning from a middle-income to a high-income economy. It argues that overcoming this trap is essential for China to achieve high-quality economic development and sustain its growth momentum. The study compares China's technological landscape with that of both developed economies and those stuck in the middle-income trap, identifying the necessity of transitioning from applied to original technology for economic leapfrogging. Through comprehensive analysis, it is highlighted that China's current technological capabilities, although leading in certain areas, predominantly remain at an intermediate level, characterized by a significant reliance on foreign core technologies and a lack of original technological innovation. The paper further explores historical contexts, policy implications, and strategic reforms required to navigate this trap, emphasizing the importance of an open policy, the cultivation of a robust innovation ecosystem, and the strategic role of government in facilitating technological progress and industrial upgrading. It draws on the experiences of developed economies and successful latecomers, advocating for a "new whole nation system" that embraces openness and global integration, rather than isolation. By analyzing the complex interplay between technology diffusion, talent migration, industrial policies, and the global geopolitical landscape, this study provides insights into the systemic reforms and strategic initiatives China must undertake. It stresses the need for a balanced approach between leveraging external technologies and fostering domestic innovation capabilities to escape the middle technology trap and secure a position as a global technology leader. The findings contribute to the broader discourse on technology-led development strategies and offer policy recommendations for economies facing similar technological and developmental challenges.
Tradition and Disruption in Latinx and Latin American Political Thought
Authors: VALDEZ INÉS , ROCCO RAYMOND , CHANG ARTURO 
Published: August 2024

Abstract
This article presents Latinx political thought as a distinctive tradition in political theory that reworks central concepts in response to historical experiences of conquest, colonialism, migration, and transnational politics. In reconstructing this tradition, we argue that its problem space converges with US-based Latin American political thought. The article first traces a genealogy of Latinx political theory and then explores three realms of theorizing around which Latinx and Latin American political thought cluster: sovereignty and state violence, peoplehood, and transnationalism. We explain how the surveyed works disrupt and enrich political theory accounts of these problems. In arguing for the recognition of this field as a tradition, the article also aims to make it intelligible as an area of concentration for PhD students in political science.
Sedentary Merchant Triumphant: The Transformation of Venetian Trading Patterns in the Long Twelfth Century
Authors: Shadrina Elena 
Published: August 2024

AbstractThis paper examines the transformation of Venetian commerce across the twelfth century, arguing that the strategies of Venetian merchants are best described using two distinct models. One was locally integrated and geographically decentralized, typical of merchants who settled abroad and became part of local societies, sometimes retaining few clear links to Venice. The other was far more centralized, characterized by short-term, profit-focused ventures originating in Venice that precluded deep entanglements in foreign economies. Both models were facilitated by the unstructured nature of Venetian overseas administration, which accommodated a degree of autonomy for expatriates while providing the infrastructure necessary for transient commerce. The decline of the integrated model began with the imperial sanctions of 1171 and culminated with the Fourth Crusade (1202–1204), after which the centralized model came to dominate. The subsequent importance of the “sedentary merchant” in Venetian trade was shaped as much by political as by economic factors.
Observations of Flocs in an Estuary and Implications for Computation of Settling Velocity
Authors: Allen R. M. , Livsey D. N. , McGill S. C. 
Published: August 2024

AbstractThe settling velocity (ws) in estuarine environments can impact whether a region is eroding or accreting sediment on the bed, yet determining this rate can be an indirect process requiring a number of assumptions. Accurate determination of ws is especially needed for numerical models to reproduce observed sediment concentrations at the appropriate timescale. We collected information on suspended sediment flocculation at a channel site (13 m deep) and a shallows site (4 m deep) within South San Francisco Estuary, alongside timeseries of flow, wave statistics, turbulent shear, and bottle samples analyzed for both ws and particle size. Using the measurements of floc size and settling velocity, we performed a sensitivity analysis on the unknown parameters in the general explicit formula for settling velocity. The collected particle size distribution data show that multiple classes of flocs are present; these are characterized as flocculi, microflocs, and macroflocs. We show that ws of flocculi is closest to ws for the full distribution. The determined parameter values lead to near‐bed mass‐weighted settling velocities (standard deviation) of 1.18 (0.55) and 0.22 (0.15) mm/s at the channel and shallows sites, respectively. Modeling efforts can use this work to help select an appropriate sediment model and parameter values.
Investigation on Chasing and Interaction of Traveling Ionospheric Disturbances Based on Multi‐Instrument
Authors: Luo Ji , Xu Jiyao , Wu Kun , Sheng Zheng 
Published: August 2024

AbstractIn this study, we use multi‐instrument observations (all‐sky imager (ASI), global navigation satellite system (GPS) receivers, digisonde) to study the interaction of nighttime medium‐scale traveling ionospheric disturbances (MSTIDs) on 13 November 2018. The most attractive aspect of this event is that the interaction appeared between two dark bands both propagated southwestward. The airglow observations show that the latter band moved faster and caught up with the former, and these two bands merged into a new one. The propagating characteristics and morphology of the MSTIDs changed during the interaction process. The simulations from the Thermosphere‐Ionosphere‐Electrodynamics General Circulation Model (TIEGCM) suggested that the ionospheric background zonal winds and electron density distributions could play essential roles in the interaction of the MSTIDs. Moreover, the merging process might be associated with the electrostatic reconnection.
Differences in Ionospheric O+ and H+ Outflow During Storms With and Without Sawtooth Oscillations
Authors: Nowrouzi N. , Kistler L. M. , Zhao K. , Lund E. J. , Mouikis C. , Payne G. , Klecker B. 
Published: August 2024

AbstractPrevious simulations have suggested that O+ outflow plays a role in driving the sawtooth oscillations. This study investigates the role of O+ by identifying the differences in ionospheric outflow between sawtooth and non‐sawtooth storms using 11 years of FAST/Time of flight Energy Angle Mass Spectrograph (TEAMS) ion composition data from 1996 through 2007 during storms driven by coronal mass ejections. We find that the storm's initial phase shows larger O+ outflow during non‐sawtooth storms, and the main and recovery phases revealed differences in the location of ionospheric outflow. On the pre‐midnight sector, a larger O+ outflow was observed during the main phase of sawtooth storms, while non‐sawtooth storms exhibited stronger O+ outflow during the recovery phase. On the dayside, the peak outflow shifts significantly toward dawn during sawtooth storms. This strong dawnside sector outflow during sawtooth storms warrants consideration.
A Robust Quantitative Method to Distinguish Runoff‐Generated Debris Flows From Floods
Authors: Cavagnaro David B. , McCoy Scott W. , Kean Jason W. , Thomas Matthew A. , Lindsay Donald N. , McArdell Brian W. , Hirschberg Jacob 
Published: August 2024

AbstractDebris flows and floods generated by rainfall runoff occur in rocky mountainous landscapes and burned steeplands. Flow type is commonly identified post‐event through interpretation of depositional structures, but these may be poorly preserved or misinterpreted. Prior research indicates that discharge magnitude is commonly amplified in debris flows relative to floods due to volumetric bulking and increased frictional resistance. Here, we use this flow amplification to develop a metric (Q*) to separate debris flows from floods based on the ratio of observed peak discharge to the theoretical maximum water discharge from rainfall runoff. We compile 642 observations of floods and debris flows and demonstrate that Q* distinguishes flow type to ∼92% accuracy. Q* allows for accurate identification of debris flows through simple channel cross‐section surveys rather than through qualitative interpretation of deposits, and therefore should increase the performance of models and engineered structures that require accurate flow‐type observations.