bluuebunny/crossref_metadata_2025_split huggingface dataset:
The motive of forgiveness in the Gospel according to Matthew
Authors: Nel Marius J. 
Published: June 2015

This article explores the importance of the motif of forgiveness in the Gospel according to Matthew. It takes the arrangement (τάξις) of Matthew as an ancient biography (βίος) of Jesus as its point of departure for describing its ethics of forgiveness. The importance of the motif of forgiveness for Matthew is apparent from the relative frequency with which it is addressed in his Gospel and from the manner in which it is interwoven with his narration of the birth, ministry and death of Jesus. Thereafter the social-historical setting of the Gospel’s initial readers is briefly described in terms of the external (a growing schism with formative Judaism) and internal challenges (intrapersonal conflict) they faced in an attempt to understand the reason for the prominence of the motif of forgiveness in it. Finally, Matthew’s view of forgiveness is systematised by describing the different agents (God, Jesus and the disciples) of forgiveness in his Gospel. The article argues that the birth, life and death of Jesus as well as his words and deeds are integrated in a clear and compelling manner into Matthew’s ethics of forgiveness. For Matthew the confession that God had forgiven his people through Jesus, is the main reason why they are compelled to forgive others. Die motief van vergifnis in die Evangelie volgens Matteus. Die artikel ondersoek die tema van vergifnis in die Evangelie volgens Matteus. Dit neem die opbou (τάξις) van Matteusas ’n antieke biografie (βίος) van Jesus as vertrekpunt vir die beskrywing van die etiek van vergifnis daarvan. Vir Matteus blyk die belangrikheid van vergifnis uit die relatiewe frekwensie waarmee dit voorkom in die Matteusevangelie en die wyse waarop dit met sy vertelling van die geboorte, bediening en dood van Jesus verweef is. Die sosio-historiese agtergrond van die Matteusevangelie se aanvanklike lesers word ook kortliks beskryf interme van die eksterne (’n groeiende skisma met formatiewe Judaïsme) en interne uitdagings (intrapersoonlike konflik) wat hulle in die gesig gestaar het in ’n poging om die rede vir die prominensie van die vergifnistema in Matteus te bepaal. Ten slotte word Matteus se siening van vergifnis gesistematiseer deur die beskrywing van die verskillende agente (God, Jesus endie dissipels) van vergifnis in sy Evangelie. Die artikel argumenteer dat die geboorte, lewe en dood van Jesus, sowel as sy woorde en dade op ‘n duidelike en oortuigende wyse in Matteus se etiek van vergifnis geïntegreer is. Vir Matteus is God se vergifnis van sy volk se sondes deur Jesus, die primêre rede waarom hulle genoodsaak is tot die vergifnis van anderse oortredings teen hulle.
Des archives mises en scène par les artistes
Authors: Boucher Marie-Pierre , Lemay Yvon 
Published: June 2015

L’utilisation des documents d’archives par les artistes contemporains offre une nouvelle perspective sur leur diffusion et leur mise en valeur. Nous verrons comment cinq artistes canadiens ont créé, chacun à leur manière, des oeuvres à partir d’archives photographiques. En effet, selon les tactiques utilisées pour sa mise en scène, l’archive jouera différents rôles : elle sera décontextualisée par Patrick Altman, comparée à une trace plus récente par Andrzej Maciejewski, intégrée à un lieu significatif par Dominique Laquerre ainsi que Dominique Blain, et réexposée selon un procédé original par Vid Ingelevics.
De l’imprimé au numérique : les défis posés aux bibliothèques collégiales depuis 40 ans
Authors: Marquis Daniel 
Published: June 2015

Un bilan du développement des bibliothèques collégiales du réseau public et privé est brossé à partir de leur création, à la fin des années 1960, jusqu’à aujourd’hui. Progressivement, ces bibliothèques se développent et dépassent le rôle passif de prestation de services et de prêt de livres pour assumer un rôle majeur dans la réussite des étudiants. Une plus grande adéquation entre les services offerts et les besoins pédagogiques des étudiants apparaît avec la formation documentaire. Progressivement, les bibliothèques, transformées en véritable « carrefour de l’information » regroupant l’audiovisuel, les centres d’aide et le soutien à l’usage du numérique, assument un rôle dans l’acquisition d’habiletés ou de compétences informationnelles.
Oregon's Hospital Payment Cap and Enrollee Out-of-Pocket Spending and Service Use
Authors: Murray Roslyn C. , Norton Edward C. , Ryan Andrew M. 
Published: August 2024

ImportanceEnrollee cost-sharing and health insurance premiums have grown alongside rising hospital prices. To control prices and price growth, the Oregon State Employee plan instituted a cap on hospital facility payments in October 2019 that was found to reduce hospital prices. Yet the program’s association with out-of-pocket spending and use among enrollees is unknown.ObjectiveTo assess the association of the Oregon State Employee Plan’s hospital payment cap with out-of-pocket spending and changes in service use among state employees enrolled in higher cost-sharing plans.Design, Setting, and ParticipantsUsing data from the Oregon All Payer All Claims database (January 2014 to December 2021), a difference-in-differences analysis was conducted to examine the association of Oregon’s hospital payment cap with enrollee out-of-pocket spending and service use. The main analysis focused on the outpatient setting, where there were significant declines in hospital prices. Changes in a subpopulation of employees enrolled in higher cost-sharing plans were also examined.Main Outcomes and MeasuresThe primary outcome was outpatient out-of-pocket spending per procedure, which included the copayment, coinsurance, and/or deductible paid at the point of service. Changes in service use were also examined by counting the number of outpatient procedures received per enrollee per year.ResultsThe outpatient sample included 1 094 083 procedures from 92 523 Oregon educators and 4 510 342 procedures from 473 621 control enrollees. During the period before implementation, Oregon educators had higher out-of-pocket spending per outpatient procedure than the control group ($69.26 vs $41.87). The hospital payment cap was associated with a $6.60, or 9.5%, reduction in out-of-pocket spending per procedure (95% CI, −12.7 to −0.5) and a 0.24, or 4.8%, increase in the number of outpatient procedures received per enrollee per year (95% CI, 0.09-0.39) among those in higher cost-sharing plans. Enrollees receiving outpatient services from October 2019 through December 2021 saved an estimated $1.8 million. However, savings for the state were $10.3 million less than they would have been absent increases in service use.Conclusions and RelevanceThe study findings suggest that enrollees may benefit from reduced out-of-pocket spending due to hospital price regulations, but states should be mindful that price regulations may inadvertently increase health care service use.
Public Health Impact of FDA’s Request for Additional Safety Data on Cytisine for Tobacco Cessation
Authors: Reddy Krishna P. , Paltiel A. David , Freedberg Kenneth A. , Rigotti Nancy A. 
Published: August 2024

ImportanceNo new tobacco cessation medication has been licensed in the US since 2006. Cytisine, a plant-based partial agonist of nicotinic acetylcholine receptors, has demonstrated safety and efficacy in several randomized clinical trials and is currently available in many countries. However, the drug is not commercially available in the US. A New Drug Application to license cytisine as a smoking cessation medication in the US is being prepared for review by the US Food and Drug Administration, whose request for additional safety data will delay submission of the application by approximately 1 year.ObjectiveTo project the potential public health impact of cytisine, and delays in its availability, as a smoking cessation aid in the US.Design, Setting, and ParticipantsThis mathematical model estimated life expectancy gains from smoking cessation for people aged 18 to 99 years in the US, reflecting the civilian, noninstitutionalized population. The model also accounted for cytisine uptake and effectiveness, as well as potential relapse among people who stop smoking.ExposureCytisine availability as a tobacco cessation treatment immediately or after 1 year.Main Outcomes and MeasuresThe main outcomes were the number of adults able to stop smoking and sustain long-term abstinence and aggregate life-years gained.ResultsThe base case includes an estimated 29.4 million US civilian noninstitutionalized adults who smoke cigarettes (age distribution, 18-24 years: 5.5%; 25-44 years: 37.3%; 45-64 years: 41.8%; ≥65 years: 15.5%). With a conservative assumption that 3.8% of these individuals would use cytisine in the first year of availability, immediate cytisine availability could lead 71 000 more people to quit smoking over 1 year and maintain long-term abstinence. This would produce more than 500 000 additional life-years compared to the status quo in which cytisine is unavailable and fewer people stop smoking. Each additional year of delay in the availability of cytisine might reduce population-level life expectancy by 10 000 years. The model results were most sensitive to changes in cytisine uptake and effectiveness.Conclusions and RelevanceSmoking cessation generates large gains in life expectancy. This mathematical model demonstrated that immediate cytisine availability, even if used successfully by only a small fraction of people who smoke, could produce major public health benefits. Given the need for new tobacco cessation pharmacotherapy options, the magnitude of cytisine’s potential public health benefits, and the morbidity and mortality associated with delay in its availability, a timely review of cytisine for approval in the US is warranted.
Prospective external validation of radiomics‐based predictive model of distant metastasis after dynamic tumor tracking stereotactic body radiation therapy in patients with non‐small‐cell lung cancer: A multi‐institutional analysis
Authors: Adachi Takanori , Nakamura Mitsuhiro , Matsuo Yukinori , Karasawa Katsuyuki , Kokubo Masaki , Sakamoto Takashi , Hiraoka Masahiro , Mizowaki Takashi 
Published: August 2024

AbstractBackground and purposeThis study aims to externally validate a predictive model for distant metastasis (DM) with computed tomography (CT)‐based radiomics features in prospectively enrolled non‐small‐cell lung cancer patients undergoing dynamic tumor‐tracking stereotactic body radiation therapy (DTT‐SBRT).Materials and methodsThe study collected retrospective data from 567 patients across 11 institutions as the training dataset and prospectively enrolled 42 patients from four institutions as the external test dataset. Four clinical features were collected, and 944 CT‐based radiomic features were extracted from gross tumor volumes. After standardization and feature selection, DM predictive models were developed using fine and gray regression (FG) and random survival forest (RSF), incorporating clinical and radiomic features, and their combinations within the training dataset. Then, the model was applied to the test dataset, dividing patients into high‐ and low‐risk groups based on medians of risk scores. Model performance was assessed using the concordance index (C‐index), and the statistical significance between groups was evaluated using Gray's test.ResultsIn the training dataset, 122 of 567 patients (21.5%) developed DM, compared to 9 of 42 patients (21.4%) in the test dataset. In the test dataset, the C‐indices of the clinical, radiomics, and hybrid models with FG were 0.559, 0.544, and 0.560, respectively, whereas those with RSF were 0.576, 0.604, and 0.627, respectively.The hybrid model with RSF, which exhibited the best predictive performance of all models, identified 7 of 23 patients (30.4%) as high risk and 2 of 19 patients (10.5%) as low risk for DM incidence in the test dataset (p = 0.116).ConclusionAlthough predictive models for DM lack significance when applied to prospectively enrolled cases undergoing DTT‐lung SBRT, the model with RSF exhibits a consistent capacity to effectively classify patients at a high risk of developing DM.
Wind‐Proof and Moisture Permeability Aerogel‐Functionalized Textile as All‐Seasonal Passive Thermal Regulators
Authors: Liu Ling , Yuan Dengsen , Hu Xueyan , Hu Peiying , Wang Jin , Li Qingwen 
Published: August 2024

AbstractIndividuals are easily threatened by heat stress or hypothermia in outdoor environments. Therefore, there is a pressing necessity for thermal regulation materials capable of adapting to temperature shocks. Herein, an aerogel‐functionalized textile as a passive thermal regulator (AT‐PTR) is designed and demonstrated, comprising a heating side composed of carbon nanotube‐modified cotton fabric and a cooling side built of silica aerogel‐functionalized poly(vinylidene‐co‐hexafluoropropene) P(VdF‐HFP) nanofibers. The AT‐PTR demonstrates exceptional solar absorption on the heating side, achieving a warming performance of 23.2 °C in cold winter. On the cooling side, its high solar reflectance and infrared emissivity facilitate a sub‐ambient cooling effect of 12.7 °C during hot summer. Moreover, outdoor field tests of the AT‐PTR conducted across various regions and seasons demonstrate an all‐seasonal outdoor human thermal management capability. Additionally, the AT‐PTR exhibits outstanding wind‐proof and moisture permeability, and heat flow can be simply attained by flipping the AT‐PTR, ensuring sustained thermal comfort for individuals across various environments.
Manganese‐Modified Aluminum Adjuvant Enhances both Humoral and Cellular Immune Responses
Authors: Li Yaxin , Wang Chenya , Lv Haoyuan , Li Jingting , Zhang Xupei , Zhang Shiyuan , Shen Qing , Wu Qianqian , Liu Yong , Peng Rui , Liu Zhuang 
Published: August 2024

AbstractAluminum adjuvants remain the most commonly used vaccine adjuvants. Being rather effective in triggering humoral immunity, however, aluminum adjuvants usually show limited abilities in activating cellular immunities. Herein, by adding manganese ions during the preparation of aluminum adjuvant, a manganese‐modified aluminum (Mn‐Al) adjuvant is obtained, which can effectively stimulate both humoral and cellular immune responses. Such Mn‐Al adjuvant can enhance antigen adsorption and promote antigen internalization by dendritic cells (DCs). Subsequently, the released Mn2+ can activate the cyclic guanosine monophosphate–adenosine monophosphate synthase‐stimulator of interferon genes pathway to further promote DC activation. When combines with the model antigen ovalbumin (OVA), the Mn‐Al‐adjuvantes vaccine can induce high levels of antigen‐specific antibody titers and high proportions of antigen‐specific cytotoxic T cells in vivo. Moreover, the Mn‐Al‐adjuvanted vaccine elicited stronger antigen‐specific humoral and cellular immune responses than high‐dose of the aluminum‐based adjuvant. Additionally, immunization of mice with OVA in the presence of the Mn‐Al adjuvant significantly inhibited the growth of B16‐OVA tumors. Furthermore, when formulated with human papillomavirus antigens, Mn‐Al‐adjuvanted vaccines show better in vivo vaccination performance than aluminum‐adjuvanted vaccines. Therefore, the manganese‐modified aluminum adjuvant may thus become a new vaccine adjuvant with the potential to replace conventional aluminum adjuvants.
Organic small grain production in the Upper Midwest and Northeast: Challenges and lessons learned
Authors: Stedden Claire G. , Silva Erin M. , Ryan Matthew R. , Mallory Ellen B. , Darby Heather , Dawson Julie C. , Hartman Alyssa , Sorrells Mark E. 
Published: August 2024

AbstractSmall grains provide agronomic benefits that are critical to the success of organic production, and opportunities within local food movements create expanded markets for small grains. However, diversifying rotations with small grains can present challenges related to production, infrastructure, and markets. Here, we draw upon over two decades of integrated research and Extension efforts to support organic small grain production in the Upper Midwest, Northeast, and other regions of the United States where these crops are underutilized. Lessons learned have led to the development of guiding principles for a systems‐level approach to support regional organic small grain production. Forming innovative partnerships between farmers, researchers, and end users is critical. This enables research, production, and markets to adjust to local needs, adapt to available infrastructure, and foster local grain economies. The key research challenges that lie ahead are also discussed, especially adapting organic grain production practices to regional conditions and changing climates. The systems‐level approach to organic small grain research highlighted here will increase the success and resilience of organic farms across the United States and expand the adoption of organic small grain production.
Bermudagrass fairway responses to various combinations of a soil surfactant and nitrogen
Authors: Sierra Augustinus I. Alejandra , Arevalo Alvarenga A. Fernanda , Schiavon Marco 
Published: August 2024

AbstractSurfactants are commonly employed in sand‐based turfgrass systems to address soil water repellency, which often results in the formation of preferential flow channels leading to non‐uniform wetting patterns. While the influence of soil moisture on nutrient dynamics is well documented, the potential of surfactants to improve N uptake remains poorly understood. A 2‐year study was conducted on ‘Celebration’ bermudagrass [Cynodon dactylon (L.)] fairway to better understand the interaction between fertility programs (296 or 586 kg N ha−1 year−1 from ammonium sulfate and 564 kg N ha−1 year−1 primarily from a controlled‐release N fertilizer) and surfactant rate and frequency (3.2 L ha−1 every 14 or 28 days, or at 6.4 L ha−1 every 28 days) on turfgrass performance, leaf N content, and soil moisture. Overall, no significant interaction was observed between surfactant treatment and fertility program. During the dry season (November to May), fertility programs influenced turfgrass performance parameters with higher N rates consistently leading to improvements in visual quality, normalized difference vegetation index, percent green cover, and dark green color index; however, no differences were observed during the rainy season (June to October). Surfactants showed no effect on turfgrass performance but led to minimal increase in leaf N content from 3.72% to 3.85%. All surfactant treatments reduced water drop penetration time at 0 cm. Moreover, surfactant treatments applied every 28 days regardless of the rate exhibited a higher volumetric water content compared to those applied every 14 days. Surfactant applications might not be an economically feasible strategy to improve leaf N content in South Florida well‐watered bermudagrass fairways.
Effect of obesity on postoperative complications in ulcerative colitis: A systematic review and meta‐analysis
Authors: Tóth L. M. , Székely H. , Rancz A. , Zolcsák Á. , Sárközi M. D. , Ábrahám S. , Földvári‐Nagy L. , Erőss B. , Hegyi P. , Miheller P. 
Published: August 2024

AbstractBackgroundThe prevalence of ulcerative colitis (UC) is around 200/100 000 people. Colectomy is required in 7.5%–40% of patients and 58.8%–94% of these operations are elective. Approximately one in two adults with UC are overweight or obese.ObjectiveOur aim was to compare postoperative complications between obese (defined by a body mass index (BMI) over 30 kg/m2) and non‐obese UC patients who underwent total proctocolectomy with ileal pouch‐anal anastomosis (IPAA).MethodsOur preregistered protocol can be found on PROSPERO (CRD42022377761). We conducted our search in three databases on the 26th of November 2022. PRISMA 2020 guideline and the Cochrane Handbook were applied. We used the GRADEpro program and the QUIPS tool. We applied a random‐effects model to pool effect sizes. We included cohort and case–control studies investigating UC patients undergoing colectomy with IPAA and reported information on postoperative complications in obese and non‐obese patients. We used mean difference (MD) for continuous variables and calculated odds ratio (OR) with a 95% confidence interval (CI) for dichotomous variables.ResultsOf the 6870 hits of our systematic search, we included three retrospective cohort studies for analyses involving 4929 patients in our research. Neither the incidence of complications at 30 days after surgery [OR = 1.08; CI: 0.65–1.79] nor the incidence of septic complications [OR = 1.11; CI: 0.85–1.46] had any clinical relevance, except for the length of hospital stay [MD = 0.36; CI:0.04–0.69]. When we assessed the risk of bias, we found that most of the aspects examined had a moderate overall risk. Our results have very low certainty of evidence.Conclusions and RelevanceOur findings suggest that obesity defined as BMI over 30 kg/m2 may not associated with an increased risk of higher rates of overall postoperative complications compared to non‐obese patients. Obesity with a cut‐off value of 30 kg/m2 does not appear to be a primary reason for prehabilitation.
Cu66 nanoclusters from hierarchical square motifs: Synthesis, assembly, and catalysis
Authors: Sun Xueli , Wang Yuchen , Wu Qingyuan , Han Ying‐Zi , Gong Xuekun , Tang Xiongkai , Aikens Christine M. , Shen Hui , Zheng Nanfeng 
Published: August 2024

AbstractThe elucidation of hierarchical assembly structure of metal nanoclusters is of fundamental importance in the context of bottom‐up fabrication and functionalization. While recent studies have provided valuable insights into the multiscale assembly patterns of gold or silver‐based nanoclusters, the success in achieving similar results for copper analogues has been notably limited. Herein, by virtue of a slow‐ligand‐release strategy, a copper nanocluster denoted as [Cu66Cl8(PPh3)8(SC2H5)32H24](SbF6)2 was synthesized, resulting in the formation of fresh hierarchical assembly structures in one‐pot. The arrangement of the metal atoms within the cluster reveals an orderly of 16 Cu4 squares, representing a rare copper nanocluster comprising square motifs. Additionally, the ligands (phosphine, thiolate, and halide) coordinate to the surface of the cluster in a regiospecific manner, displaying square patterns as well. The self‐assembly facilitated by the C‐H···F interaction between the cluster moieties and SbF6− anions further induces the formation of three‐dimensional cubes and eventually large nanocrystals. Density functional theoretical (DFT) calculations reveal that hydride atoms with low chemical shifts typically exhibit short Cu‐H distances. The cluster demonstrates moderate stability and high catalytic activity in the chemoselective hydrogenation of cyclohexanone under mild conditions.
Rapid Thermal Drying Synthesis of Nonthiolated Spherical Nucleic Acids with Stability Rivaling Thiolated DNA
Authors: Wang Xin , Yang Zhansen , Li Zihe , Huang Kunlun , Cheng Nan , Liu Juewen 
Published: August 2024

AbstractAttaching DNA oligonucleotides to gold nanoparticles (AuNPs) to prepare spherical nucleic acids (SNAs) has offered tremendous insights into surface chemistry with resulting bioconjugates serving as critical reagents in biosensors and nanotechnology. While thiolated DNA is generally required to achieve stable conjugates, we herein communicate that using a thermal drying method, a high DNA density and excellent SNA stability was achieved using nonthiolated DNA, rivaling the performance of thiolated DNA such as surviving 1 M NaCl, 2 month stability in 0.3 M NaCl and working in 50 % serum. A poly‐adenine block with as few as two consecutive terminal adenine bases is sufficient for anchoring on AuNPs. By side‐by‐side comparison with the salt‐aging method, the conjugation mechanism was attributed to competitive adenine adsorption at high temperature along with an extremely high DNA concentration upon drying. Bioanalytical applications of nonthiolated SNAs were validated in both solution and paper‐based sensor platforms, facilitating cost‐effective applications for SNAs.