bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pasteurella Multocida Infection in Cats
Authors: Lloret Albert , Egberink Herman , Addie Diane , Belák Sándor , Boucraut-Baralon Corine , Frymus Tadeusz , Gruffydd-Jones Tim , Hartmann Katrin , Hosie Margaret J , Lutz Hans , Marsilio Fulvio , Möstl Karin , Pennisi Maria Grazia , Radford Alan D , Thiry Etienne , Truyen Uwe , Horzinek Marian C 
Published: June 2013

Overview: Pasteurella species are part of the normal oral flora of cats. They are also a common cause of infection in this species and an important zoonotic agent. Infection in cats: Pasteurella species are commonly isolated from subcutaneous abscesses and pyothorax in cats. They may also cause secondary lower respiratory tract infection and have been associated with spinal empyema and meningoencephalomyelitis. Infection in humans: Disease in humans mainly occurs after a cat bite or scratch, but may also be transmitted via respiratory secretions from cats in close contact with a person. Signs of local infection after a cat bite appear in a few hours (3–6 h). Severe disease and a fatal outcome mostly occur in immunocompromised people, but have also been reported in immunocompetent healthy individuals. Cat ownership by immunocompromised people may carry a risk.
Duration of acute kidney injury and mortality in critically ill patients: a retrospective observational study
Authors: Han Seung Seok , Kim Sejoong , Ahn Shin Young , Lee Jeonghwan , Kim Dong Ki , Chin Ho Jun , Chae Dong-Wan , Na Ki Young 
Published: June 2013

Abstract

Background
The addition of relevant parameters to acute kidney injury (AKI) criteria might allow better prediction of patient mortality than AKI criteria alone. Here, we evaluated whether inclusion of AKI duration could address this issue.

Methods
AKI was defined according to the Kidney Disease: Improving Global Outcomes (KDIGO) guidelines in 2,143 critically ill patients, within 15 days of patient admission. AKI cases were categorized according to tertiles of AKI duration: 1st tertile, 1–2 days; 2nd tertile, 3–5 days; and 3rd tertile, ≥6 days. The hazard ratios (HRs) for overall survival rates in three groups were calculated after adjustment for multiple covariates compared with ICU patients without AKI as the reference group. The predictive ability for mortality was assessed by calculating the area under the curve (AUC) of the receiver operating characteristic curve.

Results
AKI increased the HRs for overall mortality, and the mortality rate increased with AKI duration: the adjusted HRs were 1.99 (1st tertile), 2.67 (2nd tertile), and 2.85 (3rd tertile) compared with the non-AKI group (all Ps < 0.001). The AUC of the ROC curve for overall mortality based on the AKI duration groups (0.716) was higher than the AUC of AKI staging using the KDIGO guidelines (0.696) (P = 0.001). When considering KDIGO stage and AKI duration together, the AUC (0.717) was also significantly higher than that using the KDIGO stage alone (P < 0.001).

Conclusions
AKI duration is an additional parameter for the prediction of mortality in critically ill patients. The inclusion of AKI duration could be considered as a refinement of the AKI criteria.
Quantifying longitudinal right ventricular dysfunction in patients with old myocardial infarction by using speckle-tracking strain echocardiography
Authors: Konishi Katsuhisa , Dohi Kaoru , Tanimura Muneyoshi , Sato Yuichi , Watanabe Kiyotaka , Sugiura Emiyo , Kumagai Naoto , Nakamori Shiro , Nakajima Hiroshi , Yamada Tomomi , Onishi Katsuya , Nakamura Mashio , Nobori Tsutomu , Ito Masaaki 
Published: June 2013

Abstract

Background
We investigated longitudinal right ventricular (RV) function assessed using speckle-tracking strain echocardiography in patient with myocardial infarction (MI), and identified the contributing factors for RV dysfunction.

Methods
We retrospectively studied 71 patients with old MI (the OMI group) and 45 normal subjects (the Control group) who underwent a transthoracic echocardiography. Global and free wall RV peak systolic strains (PSSs) in the longitudinal direction were measured by using speckle-tracking strain echocardiography. Left ventricular (LV) PSSs were measured in the longitudinal, radial and circumferential directions. Cardiac hemodynamics including peak systolic pulmonary artery pressure was also assessed non-invasively. Plasma brain natriuretic peptide (BNP) levels were measured in all patients.

Results
In the OMI group, 73% of the patients had a normal estimated peak systolic pulmonary artery pressure of less than 35 mmHg. Global and free wall RV PSS were impaired in the OMI group compared with the Control group, and these RV systolic indices were significantly associated with heart rate, logarithmic transformed plasma BNP, greater than 1 year after onset of MI, Doppler-derived estimated pulmonary vascular resistance, LV systolic indices, LV mass index, infarcted segments within a territory of the left circumflex artery and residual total occlusion in the culprit right coronary artery. Multivariable linear regression analysis indicated that reduced longitudinal LV PSS in the 4-chamber view and BNP levels ≥500 pg/ml were independently associated with reduced global and free wall RV PSS. Moreover, when patients were divided into 3 groups according to plasma BNP levels (BNP <100 pg/ml; n = 31, 100 ≤BNP <500 pg/ml; n = 24, and BNP ≥500 pg/ml; n = 16), only patients with BNP ≥500 pg/ml had a strong correlation between RV PSS and longitudinal LV PSS in the 4-chamber view (r = 0.78 for global RV PSS and r = 0.71 for free wall RV PSS, p <0.05).

Conclusion
Longitudinal RV systolic strain depends significantly on longitudinal LV systolic strain especially in patients with high plasma BNP levels, but not on estimated peak systolic pulmonary artery pressure. These results indicate that process of RV myocardial dysfunction following MI may be governed by neurohormonal activation which causing ventricular remodeling rather than increased RV afterload.
The feasibility of nurse practitioner-performed, telementored lung telesonography with remote physician guidance - ‘a remote virtual mentor’
Authors: Biegler Nancy , McBeth Paul B , Tiruta Corina , Hamilton Douglas R , Xiao Zhengwen , Crawford Innes , Tevez-Molina Martha , Miletic Nat , Ball Chad G , Pian Linping , Kirkpatrick Andrew W 
Published: June 2013

AbstractBackgroundPoint-of-care ultrasound (POC-US) use is increasingly common as equipment costs decrease and availability increases. Despite the utility of POC-US in trained hands, there are many situations wherein patients could benefit from the added safety of POC-US guidance, yet trained users are unavailable. We therefore hypothesized that currently available and economic ‘off-the-shelf’ technologies could facilitate remote mentoring of a nurse practitioner (NP) to assess for recurrent pneumothoraces (PTXs) after chest tube removal.MethodsThe simple remote telementored ultrasound system consisted of a handheld ultrasound machine, head-mounted video camera, microphone, and software on a laptop computer. The video output of the handheld ultrasound machine and a macroscopic view of the NP's hands were displayed to a remote trauma surgeon mentor. The mentor instructed the NP on probe position and US machine settings and provided real-time guidance and image interpretation via encrypted video conferencing software using an Internet service provider. Thirteen pleural exams after chest tube removal were conducted.ResultsThirteen patients (26 lung fields) were examined. The remote exam was possible in all cases with good connectivity including one trans-Atlantic interpretation. Compared to the subsequent upright chest radiograph, there were 4 true-positive remotely diagnosed PTXs, 2 false-negative diagnoses, and 20 true-negative diagnoses for 66% sensitivity, 100% specificity, and 92% accuracy for remotely guided chest examination.ConclusionsRemotely guiding a NP to perform thoracic ultrasound examinations after tube thoracostomy removal can be simply and effectively performed over encrypted commercial software using low-cost hardware. As informatics constantly improves, mentored remote examinations may further empower clinical care providers in austere settings.
Growth hormone exacerbates diabetic renal damage in male but not female rats
Authors: Whitney Jennifer L , Bilkan Christine Maric , Sandberg Kathryn , Myers Adam K , Mulroney Susan E 
Published: June 2013

AbstractBackgroundHuman and animal studies support the idea that there are sex differences in the development of diabetic renal disease. Our lab and others have determined that in addition to Ang II (through the AT1R), growth hormone (GH) contributes to renal damage in models of renal failure; however, the impact of sex and GH on the mechanisms initiating diabetic renal disease is not known. This study examined the effect of sex and GH on parameters of renal damage in early, uncontrolled streptozotocin (STZ)-induced diabetes.MethodsAdult male and female Sprague–Dawley rats were injected with vehicle (control), STZ, or STZ + GH and euthanized after 8 weeks.ResultsMild but significant glomerulosclerosis (GS) and tubulointerstitial fibrosis (TIF) was observed in both kidneys from male and female diabetic rats, with GH significantly increasing GS and TIF by 30% and 25% in male rats,but not in female rats. STZ increased TGF-β expression in both kidneys from male and female rats; however, while GH had no further effect on TGF-β protein in diabetic females, GH increased TGF-β protein in the male rat’s kidneys by an additional 30%. This sex-specific increase in renal injury following GH treatment was marked by increased MCP-1 and CD-68+ cell density. STZ also reduced renal MMP-2 and MMP-9 protein expression in both kidneys from male and female rats, but additional decreases were only observed in GH-treated diabetic male rats. The sex differences were independent of AT1R activity.ConclusionsThese studies indicate that GH affects renal injury in diabetes in a sex-specific manner and is associated with an increase in pro-inflammatory mediators.
PROJECT DEVELOPMENT OF PROFESSIONAL STANDARD “EDUCATIONAL ORGANIZATION MANAGEMENT” (part 2)
Authors: Шкляева  , Shklyaeva Nadezhda 
Published: June 2013

The bibliographical analysis of research, dedicated to definition of professional standard intension as well as overview of the sources related to this theme is given in this article. The author directs the group of
regional professional standard development. The research results on specifi cation of educational institution director job functions are presented
in this article too. The author proposes to discuss the project of regional professional standard “Educational Organization Management».
The accuracy of current methods in determining the timing of epiphysiodesis
Authors: Lee S. C. , Shim J. S. , Seo S. W. , Lim K. S. , Ko K. R. 
Published: June 2013

We compared the accuracy of the growth remaining method of assessing leg-length discrepancy (LLD) with the straight-line graph method, the multiplier method and their variants. We retrospectively reviewed the records of 44 patients treated by percutaneous epiphysiodesis for LLD. All were followed up until maturity. We used the modified Green–Anderson growth-remaining method (Method 1) to plan the timing of epiphysiodesis. Then we presumed that the other four methods described below were used pre-operatively for calculating the timing of epiphysiodesis. We then assumed that these four methods were used pre-operatively. Method 2 was the original Green–Anderson growth-remaining method; Method 3, Paley’s multiplier method using bone age; Method 4, Paley’s multiplier method using chronological age; and Method 5, Moseley’s straight-line graph method. We compared ‘Expected LLD at maturity with surgery’ with ‘Final LLD at maturity with surgery’ for each method. Statistical analysis revealed that ‘Expected LLD at maturity with surgery’ was significantly different from ‘Final LLD at maturity with surgery’. Method 2 was the most accurate. There was a significant correlation between ‘Expected LLD at maturity with surgery’ and ‘Final LLD at maturity with surgery’, the greatest correlation being with Method 2. Generally all the methods generated an overcorrected value. No method generates the precise ‘Expected LLD at maturity with surgery’. It is essential that an analysis of the pattern of growth is taken into account when predicting final LLD. As many additional data as possible are required. Cite this article: Bone Joint J 2013;95-B:993–1000.
Argyria following the use of silver-coated megaprostheses
Authors: Glehr M. , Leithner A. , Friesenbichler J. , Goessler W. , Avian A. , Andreou D. , Maurer-Ertl W. , Windhager R. , Tunn P-U. 
Published: June 2013

The aims of this study were to evaluate the incidence of local argyria in patients with silver-coated megaprostheses and to identify a possible association between argyria and elevated levels of silver both locally and in the blood. Between 2004 and 2011, 32 megaprostheses with silver coatings were implanted in 20 female and 12 male patients following revision arthroplasty for infection or resection of a malignant tumour, and the levels of silver locally in drains and seromas and in the blood were determined. The mean age of the patients was 46 years (10 to 81); one patient died in the immediate post-operative period and was excluded.Seven patients (23%) developed local argyria after a median of 25.7 months (interquartile range 2 to 44.5). Patients with and without local argyria had comparable levels of silver in the blood and aspiration fluids. The length of the implant did not influence the development of local argyria. Patients with clinical evidence of local argyria had no neurological symptoms and no evidence of renal or hepatic failure. Thus, we conclude that the short-term surveillance of blood silver levels in these patients is not required.Cite this article: Bone Joint J 2013;95-B:988–92.
Under-coracoid-around-clavicle (UCAC) loop in type II distal clavicle fractures
Authors: Soliman O. , Koptan W. , Zarad A. 
Published: June 2013

In Neer type II (Robinson type 3B) fractures of the distal clavicle the medial fragment is detached from the coracoclavicular ligaments and displaced upwards, whereas the lateral fragment, which is usually small, maintains its position. Several fixation techniques have been suggested to treat this fracture. The aim of this study was to assess the outcome of patients with type II distal clavicle fractures treated with coracoclavicular suture fixation using three loops of Ethibond. This prospective study included 14 patients with Neer type II fractures treated with open reduction and coracoclavicular fixation. Ethibond sutures were passed under the coracoid and around the clavicle (UCAC loop) without making any drill holes in the proximal or distal fragments. There were 11 men and three women with a mean age of 34.57 years (29 to 41). Patients were followed for a mean of 24.64 months (14 to 31) and evaluated radiologically and clinically using the Constant score. Fracture union was obtained in 13 patients at a mean of 18.23 weeks (13 to 23) and the mean Constant score was 96.07 (91 to 100). One patient developed an asymptomatic fibrous nonunion at one year. This study suggests that open reduction and internal fixation of unstable distal clavicle fractures using UCAC loops can provide rigid fixation and lead to bony union. This technique avoids using metal hardware, preserves the acromioclavicular joint and provides adequate stability with excellent results.Cite this article: Bone Joint J 2013;95-B:983–7.
A radiological and cadaveric study of oblique lumbar interbody fixation in patients with normal spinal anatomy
Authors: Wu A. M. , Tian N. F. , Wu L. J. , He W. , Ni W. F. , Wang X. Y. , Xu H. Z. , Chi Y. L. 
Published: June 2013

The purpose of this study was to determine whether it would be feasible to use oblique lumbar interbody fixation for patients with degenerative lumbar disease who required a fusion but did not have a spondylolisthesis. A series of CT digital images from 60 patients with abdominal disease were reconstructed in three dimensions (3D) using Mimics v10.01: a digital cylinder was superimposed on the reconstructed image to simulate the position of an interbody screw. The optimal entry point of the screw and measurements of its trajectory were recorded. Next, 26 cadaveric specimens were subjected to oblique lumbar interbody fixation on the basis of the measurements derived from the imaging studies. These were then compared with measurements derived directly from the cadaveric vertebrae. Our study suggested that it is easy to insert the screws for L1/2, L2/3 and L3/4 fixation: there was no significant difference in measurements between those of the 3-D digital images and the cadaveric specimens. For L4/5 fixation, part of L5 inferior articular process had to be removed to achieve the optimal trajectory of the screw. For L5/S1 fixation, the screw heads were blocked by iliac bone: consequently, the interior oblique angle of the cadaveric specimens was less than that seen in the 3D digital images. We suggest that CT scans should be carried out pre-operatively if this procedure is to be adopted in clinical practice. This will assist in determining the feasibility of the procedure and will provide accurate information to assist introduction of the screws. Cite this article: Bone Joint J 2013;95-B:977–82.
Double-bundle medial patellofemoral ligament reconstruction with hamstring tendon autograft and mediolateral patellar tunnel fixation
Authors: Singhal R. , Rogers S. , Charalambous C. P. 
Published: June 2013

Medial patellofemoral ligament (MPFL) reconstruction is used to treat patellar instability and recurrent patellar dislocation. Anatomical studies have found the MPFL to be a double-bundle structure. We carried out a meta-analysis of studies reporting outcomes of patellofemoral reconstruction using hamstring tendon autograft in a double-bundle configuration and patellar fixation via mediolateral patellar tunnels. A literature search was undertaken with no language restriction in various databases from their year of inception to July 2012. The primary outcome examined was the post-operative Kujala score. We identified 320 MPFL reconstructions in nine relevant articles. The combined mean post-operative Kujala score was 92.02 (standard error (se) 1.4, p = 0.001) using a fixed effects model and 89.45 (se 37.9, p = 0.02) using random effect modelling. The reported rate of complications with MPFL reconstruction was 12.5% (40 of 320) with stiffness of the knee being the most common. High-quality evidence in assessing double-bundle MPFL reconstruction is lacking. The current literature consists of a mixture of prospective and retrospective case series. High-quality randomised trials evaluating this procedure are still awaited. Cite this article: Bone Joint J 2013;95-B:900–5.
Novel epoxy resin composites containing polyaniline coated short kenaf bast fibers and polyaniline nanowires: mechanical and electrical properties
Authors: Razak Saiful Izwan Abd , Wahman Wan Aizan Wan Abdul , Yahya Mohd Yazid 
Published: June 2013

Abstract
This paper reports the preparation and characterization of newly developed composites consisting of epoxy resin (EP) matrix, polyaniline coated kenaf fiber (KF-PANI) and polyaniline nanowires (PANI-NW). It was shown that the KF-PANI had optimum reinforcing effects and gradually increased electrical conductivity to the EP matrix at 15 wt% loading. Inclusions of PANI-NW to the EP/15KF-PANI composites indicated that the electrical percolation threshold occurred at 5 wt% without significant loss in the mechanical properties. The EP/KF-PANI/PANI-NW revealed conductive composites having good mechanical integrity above the PANI-NW percolation concentration. The Fourier transform infrared (FTIR) and UV-visible spectroscopy studies showed favorable interactions and synergizing effects within the three components.
Language integration processes in linguistic area studies
Authors: Korina Natalia 
Published: June 2013

Abstract
Globalization has now become an integral part of our lives. One of the basic components of globalization is the integration process that involves all areas of human life including language evolution. We consequently look at this problem in terms of language and natural language processes influenced by a complex variety of factors—both interlinguistic and extralinguistic-focusing mainly on the linguistic contacts with emphasis on areal aspects.
Polymetamorphic greenschists with Al-rich green spinels (the Western Carpathian Mts.)
Authors: Hovorka Dušan 
Published: June 2013

AbstractDuring the course of the UNESCO/IGCP project nr. 442 (1999–2001) the present author, along with several colleagues, has described rare raw material types, used in the Neolithic/Aeneolithic, for the construction of stone implements. A metamorphic rock-type (greenschist) containing a substantial amount of Al-rich green spinels, is of special interest. This raw material type is characterized in this contribution.The rocks, which are the object of the present study, are metamorphic rocks of the greenschist association (containing monoclinic as well as rhombic amphiboles, and Al-rich green spinels in a substantial (5–20 vol. %) amount). Accessory mineralsnot necessarily encountered in each thin section, are olivine, orthopyroxene, corundum, clinozoisite, muscovite, cordierite, various plagioclases (albite and anorthite included), phlogopite, ilmenite, magnetite and sphene. The results of microprobe analyses for individual rock-forming minerals are presented. The genesis of the described rock-types is complicated; they are product of three metamorphic events (M1, M2, M3).
Comparing the corrosion behavior of nanograined and coarse-grained interstitial free steels
Authors: Dehghani Kamran , Hosseini Maryam , Nekahi Atiye 
Published: June 2013

AbstractThe corrosion behavior of nanograined (NG) IF-steel was compared with its coarse-grained (CG) counterpart. The corrosion tests were carried out using different solutions of NaCl and H2SO4. The results show that the nanostructured IF steel exhibited higher corrosion resistance (Ecorr) and lower corrosion rate (icorr). According to the corroded microstructures, extensive cracking was observed in the case of CG subjected to both chloride and acidic media, as well as localized corrosion with signs of severe pitting. The results also show that NaCl can act as an inhibitor when added to H2SO4-containg solution leading to a decrease in the detrimental effect of H2SO4.