bluuebunny/crossref_metadata_2025_split huggingface dataset:
Linear Wind-Forced Beta Plumes with Application to the Hawaiian Lee Countercurrent*
Authors: Belmadani Ali , Maximenko Nikolai A. , Mccreary Julian P. , Furue Ryo , Melnichenko Oleg V. , Schneider Niklas , Lorenzo Emanuele Di 
Published: July 2013

Abstract
Two numerical ocean models are used to study the baroclinic response to forcing by localized wind stress curl (i.e., a wind-forced β plume, which is a circulation cell developing to the west of the source region and composed of a set of zonal jets) with implications for the Hawaiian Lee Countercurrent (HLCC): an idealized primitive equation model [Regional Ocean Modeling System (ROMS)], and a global, eddy-resolving, general circulation model [Ocean General Circulation Model for the Earth Simulator (OFES)]. In addition, theoretical ideas inferred from a linear continuously stratified model are used to interpret results. In ROMS, vertical mixing preferentially damps higher-order vertical modes. The damping thickens the plume to the west of the forcing region, weakening the near-surface zonal jets and generating deeper zonal currents. The zonal damping scale increases monotonically with the meridional forcing scale, indicating a dominant role of vertical viscosity over diffusion, a consequence of the small forcing scale. In the OFES run forced by NCEP reanalysis winds, the HLCC has a vertical structure consistent with that of idealized β plumes simulated by ROMS, once the contribution of the North Equatorial Current (NEC) has been removed. Without this filtering, a deep HLCC branch appears artificially separated from the surface branch by the large-scale intermediate-depth NEC. The surface HLCC in two different OFES runs exhibits sensitivity to the meridional wind curl scale that agrees with the dynamics of a β plume in the presence of vertical viscosity. The existence of a deep HLCC extension is also suggested by velocities of Argo floats.
Vegetable oils in textile finishing applications: the action mode of wrinkle-reduction sprays and means for analyzing their performance
Authors: Stefanovic Bojan , Kostic Mirjana , Bacher Markus , Rosenau Thomas , Potthast Antje 
Published: July 2013

The effect of different aqueous emulsions of vegetable oils on the wrinkle recovery properties of 100% cotton fabric was investigated. Six vegetable oils (rapeseed oil, olive oil, coconut oil, safflower oil, linseed oil and modified sunflower oil) with different fatty acid profiles were used. The results prove that the fatty acid profile is an important factor affecting the wrinkle recovery properties of treated cotton fabrics. In general, higher concentrations of the active agent (vegetable oil) provide better wrinkle properties for treated cotton fabrics. The results suggest that better recovery from wrinkle deformation is due to the formation of a micro-film around the fibers and yarns that reduces the friction coefficient. For analysis that better monitors the complex process of fiber relaxation after deformation, an optical wrinkle tester based on grazing light analysis was developed. The technique allows more precise scanning of textile surfaces and measuring of small increments of wrinkle recovery after a spray treatment, for example. The optical wrinkle tester offers the possibility of time-dependent measurements to follow the kinetics of wrinkle relaxation and, for the first time, gives access to kinetic profiles of fiber relaxation.
The acoustics of friction and microstructure of model and apparel fabrics
Authors: Cooper Cerise , Norton Jennifer , Marshman Clive , Norton Ian 
Published: July 2013

Apparel fabrics are constructed of large numbers of fibers, spun into thread and woven and treated with sizing into final structures, giving rise to a number of different surface properties. A method to record and analyze the friction sound emitted from model fabrics (uniform, single-fiber polyester meshes) and apparel fabrics was developed and the relationship between microstructure and the sound emitted was established. The effect that surface modification (conditioning) has on sound emission was also investigated. Fabric sounds were captured as a result of friction, producing sound spectra (frequency versus amplitude), from which total noise could be calculated. This was compared to the fabrics’ microstructure. The shape of the sound spectra varied as a result of the structure of the model fabrics, with experimentally measured frequencies being comparable to predicted frequencies calculated. It is possible to produce a ‘fingerprint’ of acoustics, based on the thread diameter and aperture size of single-fiber structures. Spectra produced for apparel fabrics were broader than for the model fabrics (possibly as a result of the multifiber structure), and the level of total noise differed between the three fabrics, with total noise being strongly correlated to surface roughness and weight. A relationship between the total frictional noises emitted from surfaces of different materials has previously been investigated. Conditioning fabrics, no treatment and desizing the fabrics did not have a significant effect on surface roughness, weight or total noise.
Cilostazol strengthens the endothelial barrier of postcapillary venules from the rat mesentery in situ
Authors: Sugiura Yasoo , Morikawa Takayuki , Takenouchi Toshiki , Suematsu Makoto , Kajimura Mayumi 
Published: July 2013

Objective Although cilostazol, a phosphodiesterase 3 inhibitor, has been suggested to strengthen the endothelial barrier using cultured endothelial monolayers, its effect has not been tested in vivo. We, therefore, investigated effects of cilostazol on barrier properties of postcapillary venules of the rat in situ. Methods Cilostazol was administered to the rats through oral gavage at 4 hours before the measurements. The hydraulic permeability ( Lp) and the effective osmotic pressure (σΔπ), molecular sieving properties of microvascular walls, were estimated in single mesenteric postcapillary venules by a micro-occlusion technique, first during control perfusion and then in the presence of histamine. Results When the vessels were inflamed with histamine, cilostazol attenuated a transient increase in Lp and prevented σΔπ from falling. Furthermore, it reduced baseline Lp under a control state. Conclusion Cilostazol appears to tighten the endothelial barrier in situ, at least in part by inhibiting the cAMP-degrading enzyme in the endothelium.
Clinical tools that measure sitting posture, seated postural control or functional abilities in children with motor impairments: a systematic review
Authors: Field Debra , Livingstone Roslyn 
Published: July 2013

Objective: To identify and critically appraise clinical measurement tools used to assess sitting posture, seated postural control or functional abilities for children with motor impairment who are candidates for seating interventions. Data sources: Searches were run in 15 electronic databases along with hand searching. The search included articles published in English to December 2011. Review methods: Key terms included: posture, sitting, sitting posture, seated posture, seated postural control, sitting position, seating, wheelchair(s), outcome and assess(ment). The PRISMA statement was followed with inclusion criteria set a priori. Two reviewers independently screened titles, reviewed abstracts and identified full-text articles that met criteria. Data extraction included tool description and clinical utility. Two quality-rating scales were used to evaluate conduct of the studies and psychometric properties of the tools. Results: Of the 497 titles found in the search, 29 full-text articles met the inclusion criteria and 19 tools were identified. Tools represented all components of the International Classification of Functioning, Disability and Health for Children and Youth (ICF-CY), with emphasis on body structure and function and activity components. Evidence supporting reliability and validity varied, with small sample sizes influencing quality ratings. Evidence of the tools’ reliability was more prevalent than evidence of the tools’ validity. Only four tools reported on responsiveness, an important consideration for evaluating change. Little information on clinical utility was provided. Conclusion: Although a number of tools are available, evidence supporting their use for seating interventions is limited, as is the evidence supporting the strength of their measurement properties. Few tools address participation, environmental factors or the child’s and family’s perspective.
The effect of anaesthesia technique on maternal and cord blood ischaemia-modified albumin levels during caesarean section: A randomized controlled study
Authors: Ömür Dilek , Hacıvelioğlu Servet Özden , Oğuzalp Hüseyin , Uyan Berna , Kiraz Hasan Ali , Duman Can , Tütüncüler Funda Kırtay , Hancı Volkan 
Published: July 2013

Objective Ischaemia-modified albumin (IMA) is an early marker for various ischaemic events, including cardiac ischaemia. This study determined variations in IMA levels during caesarean section, performed under general anaesthesia or with combined spinal epidural anaesthesia. Methods Full-term, healthy pregnant women were allocated to undergo caesarean section, using either general anaesthesia or combined spinal epidural anaesthesia. IMA and albumin levels were measured in maternal serum samples taken immediately prior to caesarean section and 30 min into the procedure, as well as from serum taken from cord blood after double clamping. Results At total of 51 healthy pregnant women underwent either general anaesthesia ( n = 28) or combined spinal epidural anaesthesia ( n = 23). Within-group analysis of the general anaesthesia group showed that both IMA levels and IMA/albumin ratios were significantly higher at 30 min of surgery compared with the immediate preoperative period. Conclusions Lower IMA levels in the combined spinal epidural anaesthesia group may have been due to improved balancing of oxidative stress during caesarean section. Further research on IMA levels during caesarean section should take into account the method of anaesthesia used.
Factors associated with intensive care unit admission in patients with traumatic thoracic injury
Authors: Lin Frank Cheau-Feng , Tsai Stella Chin-Shaw , Li Ruei-Yun , Chen Hsiao-Chien , Tung Yung-Wei , Chou Ming-Chih 
Published: July 2013

Objective To identify factors associated with intensive care unit (ICU) admission in patients with traumatic thoracic injury. Methods Data for consecutive patients with thoracic trauma were collected prospectively. Outcomes were requirement for ICU care and prolonged (>7 days) ICU care. Results The study included 1333 patients, 484 (36.3%) of whom received ICU care: 125 of these (25.8%) received prolonged ICU care. Head injury, abdominal injury, injury severity score ≥16, haemothorax, chest tube placement and spinal surgery were significantly associated with ICU care. Head injury, number of rib fractures, chest drain placement, spinal surgery and extremity surgery were independent risk factors for prolonged ICU care. Conclusions Associated injury factors played a more prominent role than thoracic factors in the need for ICU and prolonged ICU care. A multidisciplinary trauma team (involving neurosurgeons, abdominal surgeons, orthopaedic surgeons and thoracic surgeons) is essential for the care of patients with traumatic thoracic injury.
Does Patient Sex Influence Cartilage Surgery Outcome?
Authors: Filardo Giuseppe , Kon Elizaveta , Andriolo Luca , Vannini Francesca , Buda Roberto , Ferruzzi Alberto , Giannini Sandro , Marcacci Maurilio 
Published: July 2013

Background: Sexual dimorphism in humans has already been documented at different levels, and preliminary findings also suggest the importance of patient sex on clinical outcome in the treatment of cartilage lesions. Purpose: To document and analyze the influence of sex on clinical outcome in a large cohort of patients treated with a cartilage regenerative procedure for knee chondral lesions and prospectively followed at midterm follow-up. Study Design: Cohort study; Level of evidence, 3. Methods: A total of 250 knees were treated with matrix-assisted autologous chondrocyte transplantation (MACT) and prospectively evaluated with International Knee Documentation Committee (IKDC), EuroQol visual analog scale (EQ-VAS), and Tegner scores at 1-, 2-, and minimum 5-year follow-ups to compare results obtained in men and women. The lesions were focal International Cartilage Repair Society grade III-IV chondral knee defects involving femoral condyles, trochleae, and patellae. Two homogeneous groups of 56 male patients and 56 female patients were then selected by a blinded statistician for a matched-pair analysis. Results: A statistically significant improvement in all the scores in both men and women was observed in the general population. The IKDC subjective score showed better results for men at all follow-up times: at 5 years, the mean IKDC subjective score was 79.5 ± 18.6 versus 64.3 ± 20.2 for men and women, respectively ( P < .0005), and the same trend was confirmed with the EQ-VAS and Tegner scores. The matched-pair analysis confirmed the difference of final results achieved (74.1 ± 19.8 vs 63.7 ± 20.2, respectively; P = .006). However, men and women started with different preoperative levels, and the analysis of the improvement obtained was not significantly different. Finally, when scores were standardized for each patient, according to the mean score typical for the corresponding age and sex category in a healthy population, a sex-related difference was not confirmed at any of the follow-ups. Etiological factors, lesion site, and preinjury activity level differed in women and men of the general population and were the confounding factors responsible for the different outcome not confirmed by the analysis of homogeneous cohorts of patients. Conclusion: Women have a different knee chondral lesion pattern and more often have unfavorable conditions related to the cause of injury, site, and activity level, and they also have lower raw, not standardized, scores. However, a matched-pair analysis with data standardized for the specific patient categories showed that, on equal terms, women have the same possibilities for successful outcome as men after surgical treatment for knee cartilage regeneration.
Use of a Bioactive Scaffold to Stimulate Anterior Cruciate Ligament Healing Also Minimizes Posttraumatic Osteoarthritis After Surgery
Authors: Murray Martha M. , Fleming Braden C. 
Published: July 2013

Background: Although anterior cruciate ligament (ACL) reconstruction is the treatment gold standard for ACL injury, it does not reduce the risk of posttraumatic osteoarthritis. Therefore, new treatments that minimize this postoperative complication are of interest. Bioenhanced ACL repair, in which a bioactive scaffold is used to stimulate healing of an ACL transection, has shown considerable promise in short-term studies. The long-term results of this technique and the effects of the bioenhancement on the articular cartilage have not been previously evaluated in a large animal model. Hypotheses: (1) The structural (tensile) properties of the porcine ACL at 6 and 12 months after injury are similar when treated with bioenhanced ACL repair, bioenhanced ACL reconstruction, or conventional ACL reconstruction, and all treatments yield results superior to untreated ACL transection. (2) After 1 year, macroscopic cartilage damage following bioenhanced ACL repair is similar to that in bioenhanced ACL reconstruction and less than in conventional ACL reconstruction and untreated ACL transection. Study Design: Controlled laboratory study. Methods: A total of 64 Yucatan mini-pigs underwent ACL transection and randomization to 4 experimental groups: no treatment, conventional ACL reconstruction, bioenhanced ACL reconstruction using a bioactive scaffold, and bioenhanced ACL repair using a bioactive scaffold. The biomechanical properties of the ligament or graft were examined and macroscopic assessments of the cartilage surfaces were performed after 6 and 12 months of healing. Results: The structural properties (ie, linear stiffness, yield, and maximum loads) of the ligament after bioenhanced ACL repair were not significantly different from those in bioenhanced ACL reconstruction or conventional ACL reconstruction but were significantly greater than those in untreated ACL transection after 12 months of healing. Macroscopic cartilage damage after bioenhanced ACL repair was significantly less than that in untreated ACL transection and bioenhanced ACL reconstruction, and there was a strong trend ( P = .068) for less macroscopic cartilage damage than in conventional ACL reconstruction in the porcine model at 12 months. Conclusion: Bioenhanced ACL repair produces a ligament that is biomechanically similar to an ACL graft and provides chondroprotection to the joint after ACL surgery. Clinical Relevance: Bioenhanced ACL repair may provide a new, less invasive treatment option that reduces cartilage damage following joint injury.
Topographic Analysis of the Glenoid and Proximal Medial Tibial Articular Surfaces
Authors: Gupta Anil K. , Forsythe Brian , Lee Andrew S. , Harris Joshua D. , McCormick Frank , Abrams Geoffrey D. , Verma Nikhil N. , Romeo Anthony A. , Inoue Nozomu , Cole Brian J. 
Published: July 2013

Background: Current knowledge is lacking concerning the appropriate site of osteochondral allograft harvest to match glenoid shape for the purposes of glenoid resurfacing. This has led to difficulty with adequate restoration of the geometry of the glenoid with currently available techniques. Hypothesis: The medial tibial plateau will provide a suitable osteochondral harvest site because of its concavity and anatomic similarity to the glenoid. Study Design: Descriptive laboratory study. Methods: Computed tomography (CT) was performed on 4 cadaveric proximal tibias and 4 scapulae, allowing for 16 glenoid-tibial comparative combinations. Three-dimensional CT models were created and exported into point-cloud models. A local coordinate map of the glenoid and medial tibial plateau articular surfaces was created. Two zones of the medial tibial articular surface (anterior and posterior) were quantified. The glenoid articular surface was defined as a best-fit circle of the glenoid articular surface maintaining a 2-mm bony rim. This surface was virtually placed on a point on the tibial articular surface in 3D space. The tibial surface was segmented, and its 3D surface orientation was determined with respect to its surface. The 3D orientation of the glenoid surface was reoriented so that the direction of the glenoid surface matched that of the tibial surface. The least distances between the point-clouds on the glenoid and tibial surfaces were calculated. The glenoid surface was rotated 360° in 1° increments, and the mean least distance was determined at each rotating angle. Results: When the centroid of the glenoid surface was placed on the medial tibial articular surface, it covered approximately two-thirds of the anterior or posterior tibial surfaces. Overall, the mean least distance difference in articular congruity of all 16 glenoid–medial tibial surface combinations was 0.74 mm (standard deviation, ±0.13 mm). The mean least distance difference of the anterior and posterior two-thirds of the medial tibial articular surface was 0.72 mm (±0.13 mm) and 0.76 mm (±0.16 mm), respectively. There was no significant difference between the anterior and posterior two-thirds of the tibia with regard to topographic match of the glenoid ( P = .187). Conclusion: The findings suggest that the medial tibial articular surface provides an appropriate anatomic match to the glenoid articular surface. Both the anterior and posterior two-thirds of the medial tibial articular surface are potential sites for osteochondral graft harvest. Clinical Relevance: This method can be applied to future studies evaluating the ideal sites of graft harvest to treat zonal glenoid bone wear and/or loss.
Risk Factors for Recurrent Anterior Cruciate Ligament Reconstruction
Authors: Wasserstein David , Khoshbin Amir , Dwyer Tim , Chahal Jaskarndip , Gandhi Rajiv , Mahomed Nizar , Ogilvie-Harris Darrell 
Published: July 2013

Background: Anterior cruciate ligament reconstruction (ACLR) is routinely performed for symptomatic instability. Although it is a common procedure, there remain differences in surgical technique. Hospital administrative records in a public health care system were used to investigate the effect of patient, provider, and surgical factors on the risk of revision ACLR. Purpose: To define the rate and risk factors for ACL reoperation in Ontario, Canada, including both ipsilateral revision and contralateral primary procedures. Study Design: Cohort study; Level of evidence, 3. Methods: All primary elective ACLR procedures performed in Ontario (July 2003 to March 2008) in patients aged 15 to 60 years were identified via physician billing and hospital databases. Revision and contralateral ACLR were sought until January 2012. Patient factors (age, sex, comorbidity, income quintile, length of index hospital admission), provider factors (surgeon volume, academic hospital status), and surgical factors (allograft vs autograft; fixation type [screw, button, staple]; concomitant operative procedures) were used as covariates in a Cox proportional hazards survivorship model to generate hazard ratios (HRs) with confidence intervals (CIs) (α = .05). Kaplan-Meier survivorship curves with ACL revision as the end point were generated. Results: A total of 12,967 ACLR procedures with a mean follow-up of 5.2 years were eligible for study using preset criteria. The revision rate was 2.6% (mean ± SD, 2.91 ± 1.71 years to revision). The rate of primary contralateral ACLR was 4.6% (mean, 2.95 ± 1.81 years). In the Cox model, younger age (15-19 years) (HR, 2.1; 95% CI, 1.5-2.9; P < .001), ACLR performed at an academic hospital (HR, 1.6; 95% CI, 1.2-2.1; P < .001), and the use of allograft (HR, 1.7; 95% CI, 1.1-2.6; P = .02) significantly increased the risk of revision ACLR. Only younger age (HR, 2.1; 95% CI, 1.6-2.7; P < .001) was associated with an increased risk of contralateral ACLR. Conclusion: Contralateral ACLR was more frequent than revision ACLR in this population, while both surgical procedures were most common in patients younger than 20 years. Academic hospital status, but not surgeon volume, as well as the use of allograft also increased the risk for revision ACLR.
A Novel c.776_777insA Mutation in CLN1 Leads to Infantile Neuronal Ceroid Lipofuscinosis
Authors: Miller Jake N. , Pearce David A. 
Published: July 2013

The neuronal ceroid lipofuscinoses are the most common autosomal recessive neurodegenerative disorders in children, with a worldwide incidence of 1 in 100 000 live births. Multiple clinical variants are caused by more than 400 mutations in at least 14 different genes. These progressive genetic disorders primarily manifest in the central nervous system because of an extensive loss of neurons, specifically in the cerebral and cerebellar cortices. Patients with mutations in CLN1, which encodes palmitoyl-protein thioesterase 1 (PPT1), primarily manifest with infantile neuronal ceroid lipofuscinosis (Haltia-Santavuori disease). Affected children usually present between 1 and 2 years of age and typically die by 8 to 13 years of age. We describe a patient with infantile neuronal ceroid lipofuscinosis with a novel c.776_777insA mutation in CLN1. This insertion induces a frameshift and a premature stop codon late within the CLN1 messenger RNA (mRNA) transcript which is likely recognized by nonsense-mediated translation repression, decreasing PPT1 abundance.