bluuebunny/crossref_metadata_2025_split huggingface dataset:
Enhancing ultrasound education in obstetrics and gynecology in Germany: insights and innovations from postgraduate training
Authors: Schlapp Marie-Sovie , Wittek Agnes , Neubauer Ricarda , Geipel Annegret , Gembruch Ulrich , Strizek Brigitte , Recker Florian 
Published: June 2024

Abstract
Background
Ultrasound (US) has become integral to obstetrics and gynecology (Ob/Gyn), necessitating proficient training during residency. Despite its clinical importance, there is a perceived gap in the quality and structure of postgraduate ultrasound education in Germany.

Methods
A cross-sectional survey was conducted among Ob/Gyn residents in Germany from October 2023 to March 2024, using the LimeSurvey platform. The survey, distributed via email, social media, and physical flyers, garnered 211 participants, with 115 completing all sections. The questionnaire covered demographic details, US training experiences, and the perceived importance of US in clinical practice.

Results
Although US was highly valued by respondents, with an average of 26.1% of their clinical activity devoted to it, there was significant dissatisfaction with the training quality. Key issues included inadequate supervision, the necessity of self-training, and low participation in certification courses. Despite 93.0% awareness of professional US organizations like the German Society for Ultrasound in Medicine (DEGUM), engagement with structured training programs was minimal.

Discussion
The study highlights a critical need for standardized US training protocols and curricular reform in Ob/Gyn residencies in Germany. The discrepancy between the recognized importance of US and the quality of training indicates a pressing need for improvements. Addressing these gaps through comprehensive, structured educational reforms could significantly enhance the proficiency and confidence of future Ob/Gyn specialists, ultimately improving patient care.
From the mantle source to the crustal sink: magmatic differentiation and sulfide saturation of the Paleoproterozoic komatiites of the Central Lapland Greenstone Belt, Finland
Authors: Virtanen Ville J. , Höytiä Henri M.A. , Iacono-Marziano Giada , Yang Shenghong , Moilanen Marko , Törmänen Tuomo 
Published: June 2024

AbstractPaleoproterozoic (2.05 Ga) komatiites are widespread in the Central Lapland Greenstone Belt (CLGB), northern Finland. Close association with sulfur (S)-rich country rocks and spatiotemporal connection with the Cu-Ni(-PGE) deposits of Kevitsa and Sakatti make these komatiites interesting targets for sulfide deposit exploration. We provide whole-rock geochemical data from Sattasvaara komatiites and combine it with literature data to form a geochemical database for the CLGB komatiites. We construct a model for the komatiites from adiabatic melting of the mantle source to fractional crystallization at crustal conditions. Using MELTS, we calculate three parental melts (MgO = 20.6–25.7 wt%) in equilibrium with Fo92, Fo93, and Fo94 olivine for the CLGB komatiites. Based on REEBOX PRO simulations, these parental melts can form from a single mantle source by different pressures and degrees of melting when the potential temperature is 1575–1700 °C. We calculate ranges of S contents for the parental melts based on the different mantle melting conditions and degrees of melting. We use Magma Chamber Simulator to fractionally crystallize the parental melt at crustal conditions. These simulations reproduce the major element oxide, Ni, Cu, and S contents from our komatiite database. Simulated Ni contents in olivine are compatible with literature data from Kevitsa and Sakatti, hence providing a baseline to identify Ni-depleted olivine in CLGB komatiites and related intrusive rocks. We show that fractional crystallization of the komatiitic parental melt can form either Ni-rich or Cu-rich sulfide melt, depending on the initial Ni and S content of the parental melt.
Full Hill-type muscle model of the I1/I3 retractor muscle complex in Aplysia californica
Authors: Sukhnandan Ravesh , Chen Qianxue , Shen Jiayi , Pao Samantha , Huan Yu , Sutton Gregory P. , Gill Jeffrey P. , Chiel Hillel J. , Webster-Wood Victoria A. 
Published: June 2024

AbstractThe coordination of complex behavior requires knowledge of both neural dynamics and the mechanics of the periphery. The feeding system of Aplysia californica is an excellent model for investigating questions in soft body systems’ neuromechanics because of its experimental tractability. Prior work has attempted to elucidate the mechanical properties of the periphery by using a Hill-type muscle model to characterize the force generation capabilities of the key protractor muscle responsible for moving Aplysia’s grasper anteriorly, the I2 muscle. However, the I1/I3 muscle, which is the main driver of retractions of Aplysia’s grasper, has not been characterized. Because of the importance of the musculature’s properties in generating functional behavior, understanding the properties of muscles like the I1/I3 complex may help to create more realistic simulations of the feeding behavior of Aplysia, which can aid in greater understanding of the neuromechanics of soft-bodied systems. To bridge this gap, in this work, the I1/I3 muscle complex was characterized using force-frequency, length-tension, and force-velocity experiments and showed that a Hill-type model can accurately predict its force-generation properties. Furthermore, the muscle’s peak isometric force and stiffness were found to exceed those of the I2 muscle, and these results were analyzed in the context of prior studies on the I1/I3 complex’s kinematics in vivo.
Impact of aging on crossmodal attention switching
Authors: Schils Ludivine A. P. , Koch Iring , Huang Pi-Chun , Hsieh Shulan , Stephan Denise N. 
Published: June 2024

AbstractPrevious studies on crossmodal visual-auditory attention switching using a spatial discrimination task showed performance costs when the target modality changed relative to when it repeated. The present study (n = 42 for each age group) examined age-related changes in crossmodal attention switching by asking young (age range 19 to 30 years old) and older (age range 64 to 80 years old) participants to respond to unimodal central cues and bimodal lateralized stimuli. The participants’ task was to indicate the location of the target in the relevant modality using button presses. Results showed general attention switch costs. Additionally, we found no specific age-related increase of attention switch costs (no difference in performance between switch and repetition of target modality), but age-related increased mixing costs (decreased performance for repetition in modality-mixed condition compared to single target modality). Moreover, spatial distraction produced a crossmodal congruency effect, which was only slightly larger in older adults. Taken together, age-related increased mixing costs suggest a general difficulty with maintaining more than one task, but no specific age-related crossmodal impairment in crossmodal attention switching.
Loss of insulin-expressing extra-islet cells in type 1 diabetes is accompanied with increased number of glucagon-expressing extra-islet cells
Authors: Granlund Louise , Lundberg Marcus 
Published: June 2024

AbstractThe presence of remaining insulin-positive cells in type 1 diabetes (T1D) is well-known. These cells are part of islets or appear as extra-islet insulin-positive cells scattered in the exocrine parenchyma. The latter are poorly described, and the presence of scattered endocrine cells expressing other islet hormones than insulin has not been explored. This study aimed to compare the extra-islet insulin- or glucagon-positive cells concerning their frequency, transcription-factor expression, and mitotic activity in subjects with and without T1D. Multispectral imaging was used to examine extra-islet cells by staining for insulin, glucagon, ARX, PDX1, and Ki67. This was done in well-preserved pancreatic tissue obtained from heart-beating organ donors with or without T1D. In three T1D donors, lobes with insulin-containing islets (ICI) were found. Within these, a higher frequency of extra-islet insulin-positive cells was observed compared to lobes with insulin-deficient islets (IDI). Increased frequency of glucagon-positive extra-islet cells was observed in donors with T1D (median 53 cells/mm2) when compared with non-diabetic donors (11 cells/mm2, p = 0.004). Proliferating endocrine cells were present in donors with, and without T1D, as demonstrated by Ki67-positive staining (0–3% of the cells expressing insulin or glucagon). The reduced frequency of extra-islet insulin-positive cells in lobes with IDI in donors with T1D suggests that the pathological mechanism causing beta cell demise in T1D affects entire lobes. The presence of an increased frequency of glucagon-positive extra-islet cells supports the notion of a preserved capacity to regenerate the endocrine pancreas in donors with T1D.
Can blood-based markers predict RECIST progression in non-small cell lung cancer treated with immunotherapy?
Authors: Yeghaian Melda , Tareco Bucho Teresa M. , de Bruin Melissa , Schmitz Alexander , Bodalal Zuhir , Smit Egbert F. , Beets-Tan Regina G. H. , van den Broek Daan , Trebeschi Stefano 
Published: June 2024

Abstract
Purpose
In this study, we aimed to evaluate the potential of routine blood markers, serum tumour markers and their combination in predicting RECIST-defined progression in patients with stage IV non-small cell lung cancer (NSCLC) undergoing treatment with immune checkpoint inhibitors.

Methods
We employed time-varying statistical models and machine learning classifiers in a Monte Carlo cross-validation approach to investigate the association between RECIST-defined progression and blood markers, serum tumour markers and their combination, in a retrospective cohort of 164 patients with NSCLC.

Results
The performance of the routine blood markers in the prediction of progression free survival was moderate. Serum tumour markers and their combination with routine blood markers generally improved performance compared to routine blood markers alone. Elevated levels of C-reactive protein (CRP) and alkaline phosphatase (ALP) ranked as the top predictive routine blood markers, and CYFRA 21.1 was consistently among the most predictive serum tumour markers. Using these classifiers to predict overall survival yielded moderate to high performance, even when cases of death-defined progression were excluded. Performance varied across the treatment journey.

Conclusion
Routine blood tests, especially when combined with serum tumour markers, show moderate predictive value of RECIST-defined progression in NSCLC patients receiving immune checkpoint inhibitors. The relationship between overall survival and RECIST-defined progression may be influenced by confounding factors.
Hyperparasitism in bat flies (Diptera: Streblidae): new records and interaction networks in the Neotropics
Authors: López-Rivera Camila , Robayo-Sánchez Laura Natalia , Ramírez-Hernández Alejandro , Cortés-Vecino Jesús Alfredo , Cuéllar-Sáenz Jerson Andrés , Villar Juan Diego , Rivera-Páez Fredy Arvey , Ossa-López Paula Andrea , Henao-Osorio José Jaime , Cardona-Giraldo Alexandra , Ospina-Pérez Erika Mayerly , Hidalgo Marylin , Ramírez-Chaves Héctor E. 
Published: June 2024

AbstractHyperparasitism is defined as the interaction where one parasite is infected by another parasite. In bat flies (Streblidae and Nycteribiidae), both hyperparasites and microparasites (bacteria, viruses, fungi, and arthropods such as mites) have been documented. Fungi belonging to the order Laboulbeniales are microscopic parasites of a wide diversity of arthropod hosts. Three genera exclusively target bat flies: Arthrorhynchus, which parasitizes species within Nycteribiidae in the Eastern Hemisphere, while genus Gloeandromyces and Nycteromyces parasitize Streblidae in the Western Hemisphere. Among the hyperparasitic arthropods, mites of family Neothrombidiidae, particularly the monospecific genus Monunguis, are known to parasitize bat flies. Here we present the first records of the hyperparasites Monunguis streblida and Gloeandromyces pageanus f. polymorphus parasitizing Streblidae bat flies in Colombia and a summary of these hyperparasitic interactions in the Neotropics. We detected fungi and mites parasitizing bat flies that were collected in the Magdalena River Basin, Colombia, in field expeditions in 2018, 2022, and 2023. We identified 17 bat flies and two species of hyperparasites, specifically M. streblida and the fungi Gloeandromyces. Our search for reports of these interactions in the Neotropics revealed that seven species of Trichobius (Streblidae) are parasitized by M. streblida, whereas Paratrichobius longicrus (Streblidae) is parasitized by Gloeandromyces pageanus f. polymorphus. These interactions have been reported in 11 countries, but our records are the first of M. streblida and Laboulbeniales fungi parasitizing bat flies in Colombia. So far, a total of 14 species of fungi and one species of mite have been associated with 19 species of bat flies, which in turn, are linked to 15 species of Neotropical bats.
Clinical results of two different three-dimensional plate types for the treatment of mandibular angle fractures: a retrospective analysis
Authors: Pfister Jelena , Shazwani Farah Nur , Müller Martin , Burkhard John-Patrik 
Published: June 2024

Abstract
Objectives
The purpose of this study was to compare two different designs of three-dimensional osteosynthesis plates for their suitability in the treatment of mandibular angle fractures in terms of sufficient fracture healing and concomitant complications.

Materials and methods
Retrospectively a total of 54 patients with 56 mandibular angle fractures were evaluated. Two different types of three-dimensional plates from the Medartis Trilock system were analyzed: (A) Square design plate (☐-plate) with a thickness of 1.0 mm, and (B) triangular-shaped 3D-plate (△-plate) with a thickness of 1.3 mm. Patient demographics, fracture mechanism and intraoperative details were recorded during an average follow-up period of 1 year.

Results
The utilization of △-plates was observed to entail a considerably lengthier surgical time in contrast to ☐-plate systems (P = 0.037). The application of △-plate showed a tendency of higher incidence of major complications than ☐-plate (P = 0.06), as evidenced by the occurrence of non-union in 2 out of 22 cases, resulting in higher surgical revision rate for △-plate (P = 0.027).

Conclusion
Sufficient treatment of mandibular angle fractures is feasible by using 1.0 mm thick, square shaped three-dimensional plate systems. The use of thicker three-dimensional osteosynthesis plates seems to significantly increase the operating time and complication rates, whereby the geometry of the plate seems to have an influence.

Clinical relevance
The plate design could have an impact on treatment outcomes of mandibular angle fractures.

Trial registration number
Not applicable.
The impact of family involvement on students’ social-emotional development: the mediational role of school engagement
Authors: Martinez-Yarza Nerea , Solabarrieta-Eizaguirre Josu , Santibáñez-Gruber Rosa 
Published: June 2024

AbstractFamily involvement has been identified as a mechanism that explains the differences in academic performance and well-being between students from different socioeconomic backgrounds. The implications of family involvement in students' non-academic outcomes have often been overshadowed by a focus on the academic domain. This study focuses on one type of non-academic attributes which is currently most critical to navigate in school and beyond: social-emotional development. In addition to that, the potential mediating role of school engagement in the association between family involvement and students' social-emotional development remains to be explored. This study aimed to investigate whether family involvement was associated with students' school engagement and social-emotional development and to clarify the underlying mechanism in the relationship. The sample consisted of 170 students from 8 to 17 years old and their parents who live in economically vulnerable situations and experience social exclusion. The analyses were performed using Jamovi statistical software and a GLM Mediation Model module. To address the research objectives, a series of mediation analysis were performed to fit the hypothesized relations among the study variables. The mediational analysis suggested that home-based family involvement could not predict students' social-emotional development, and that the effect of home-based family involvement on students' social-emotional development was fully mediated by school engagement, a variable not included in previous research. The results suggest that families who are actively engaged in their child's education at home positively influence students' level of participation in school, which, in turn, promotes the development of students' social-emotional competences.
Who is really an excellent university student and how to identify them? A development of a comprehensive framework of excellence in higher education
Authors: Mašková Ivana , Kučera Dalibor , Nohavová Alena 
Published: June 2024

AbstractThis paper addresses the need for a more comprehensive framework of excellence in higher education, which goes beyond academic achievement alone, placing emphasis on its integration with personal characteristics, and acknowledging the diversity in the student population. Two research studies were conducted to establish this comprehensive framework. The pilot study aimed to offer a conceptual definition of the excellent university student according to the perceptions of the academic community. The study, which involved 26 teachers and 159 students, was informed by teacher interviews, student essays, and focus group discussions. The established conceptual framework of excellence was based on a subset of essential attributes that could be embodied by a real student. The conceptual framework comprises facets of expertness, proactive learning, and being a good person organised within the dimensions of educational and personal excellence. It is complemented by academic achievement and underpinned by genuine study motivation. Building upon the findings of the pilot study, the main study aimed to develop and implement a systematic procedure for identifying excellent students. The study, which involved 53 teachers and 112 students, was based on a multisource assessment of multiple contextually relevant criteria of excellence. The identification procedure involved three phases: teacher nomination and assessment, academic achievement assessment, and peer assessment. As a result, 10 excellent students were identified who met all the conceptual criteria of excellence. In conclusion, this paper presents a comprehensive conceptual and methodological framework for defining and identifying excellent university students, grounded in both theoretical principles and empirical findings.
Assimilating human feedback from autonomous vehicle interaction in reinforcement learning models
Authors: Fox Richard , Ludvig Elliot A. 
Published: June 2024

AbstractA significant challenge for real-world automated vehicles (AVs) is their interaction with human pedestrians. This paper develops a methodology to directly elicit the AV behaviour pedestrians find suitable by collecting quantitative data that can be used to measure and improve an algorithm's performance. Starting with a Deep Q Network (DQN) trained on a simple Pygame/Python-based pedestrian crossing environment, the reward structure was adapted to allow adjustment by human feedback. Feedback was collected by eliciting behavioural judgements collected from people in a controlled environment. The reward was shaped by the inter-action vector, decomposed into feature aspects for relevant behaviours, thereby facilitating both implicit preference selection and explicit task discovery in tandem. Using computational RL and behavioural-science techniques, we harness a formal iterative feedback loop where the rewards were repeatedly adapted based on human behavioural judgments. Experiments were conducted with 124 participants that showed strong initial improvement in the judgement of AV behaviours with the adaptive reward structure. The results indicate that the primary avenue for enhancing vehicle behaviour lies in the predictability of its movements when introduced. More broadly, recognising AV behaviours that receive favourable human judgments can pave the way for enhanced performance.
WSMOTER: a novel approach for imbalanced regression
Authors: Camacho Luís , Bacao Fernando 
Published: June 2024

AbstractAlthough the imbalanced learning problem is best known in the context of classification tasks, it also affects other areas of learning algorithms, such as regression. For regression, the problem is characterized by the existence of a continuous target variable domain and the need for models capable of making accurate predictions about rare events. Furthermore, such rare events with a real-value target are often the ones with greater interest in having models that can predict them. In this paper, we propose the novel approach WSMOTER (Weighting SMOTE for Regression) to tackle the imbalanced regression problem, which, according to the experimental work we present, outperforms currently available solutions to the problem.
Hunting and Fishing CEOs: Environmental Plunderers or Saviors?
Authors: Covington Thomas , Swidler Steve , Yost Keven 
Published: June 2024

AbstractCEOs who participate in hunting and fishing benefit by appreciating natural environments and permanently consuming natural resources. We examine whether CEOs who hunt and fish make different environmental decisions and find that firms led by CEOs who obtain the most hunting and fishing licenses have lower environmental performance as measured by MSCI-KLD. This effect is strongest in the environmental category of climate change but also extends to pollution, waste, and the protection of natural capital. Furthermore, firms led by CEOs with the most hunting and fishing licenses are significantly more likely to pay a regulatory settlement for an environmental regulatory infraction.
Finding orientations of supersingular elliptic curves and quaternion orders
Authors: Arpin Sarah , Clements James , Dartois Pierrick , Eriksen Jonathan Komada , Kutas Péter , Wesolowski Benjamin 
Published: June 2024

AbstractAn oriented supersingular elliptic curve is a curve which is enhanced with the information of an endomorphism. Computing the full endomorphism ring of a supersingular elliptic curve is a known hard problem, so one might consider how hard it is to find one such orientation. We prove that access to an oracle which tells if an elliptic curve is $$\mathfrak {O}$$
O
-orientable for a fixed imaginary quadratic order $$\mathfrak {O}$$
O
provides non-trivial information towards computing an endomorphism corresponding to the $$\mathfrak {O}$$
O
-orientation. We provide explicit algorithms and in-depth complexity analysis. We also consider the question in terms of quaternion algebras. We provide algorithms which compute an embedding of a fixed imaginary quadratic order into a maximal order of the quaternion algebra ramified at p and $$\infty $$
∞
. We provide code implementations in Sagemath (in Stein et al. Sage Mathematics Software (Version 10.0), The Sage Development Team, http://www.sagemath.org, 2023) which is efficient for finding embeddings of imaginary quadratic orders of discriminants up to O(p), even for cryptographically sized p.