bluuebunny/crossref_metadata_2025_split huggingface dataset:
Risk of Recurrent Arterial Ischemic Stroke in Childhood
Authors: Fullerton Heather J. , Wintermark Max , Hills Nancy K. , Dowling Michael M. , Tan Marilyn , Rafay Mubeen F. , Elkind Mitchell S.V. , Barkovich A. James , deVeber Gabrielle A. ,   VIPS Investigators, Plumb Patricia A. , Benedict Susan L. , Bernard Timothy J. , Fox Christine K. , Friedman Neil R. , Lo Warren D. , Ichord Rebecca N. , Mackay Mark T. , Kirton Adam , Hernandez-Chavez Marta I. , Humphreys Peter , Jordan Lori C. , Sultan Sally , Rivkin Michael J. , Titomanlio Luigi , Kovacevic Gordana S. , Yager Jerome Y. , Amlie-Lefond Catherine , Dlamini Nomazulu , Condie John , Yeh Ann , Kneen Rachel , Bjornson Bruce , Pergami Paola , Zou Li Ping , Elbers Jorina M. , Abdalla Abdalla , Chan Anthony K. , Farooq Osman , Lim Mingming J. , Carpenter Jessica L. , Pavlakis Steven , Wong Virginia C. , Forsyth Robert 
Published: November 2015

Background and Purpose—
Published cohorts of children with arterial ischemic stroke (AIS) in the 1990s to early 2000s reported 5-year cumulative recurrence rates approaching 20%. Since then, utilization of antithrombotic agents for secondary stroke prevention in children has increased. We sought to determine rates and predictors of recurrent stroke in the current era.

Methods—
The Vascular Effects of Infection in Pediatric Stroke (VIPS) study enrolled 355 children with AIS at 37 international centers from 2009 to 2014 and followed them prospectively for recurrent stroke. Index and recurrent strokes underwent central review and confirmation, as well as central classification of causes of stroke, including arteriopathies. Other predictors were measured via parental interview or chart review.

Results—
Of the 355 children, 354 survived their acute index stroke, and 308 (87%) were treated with an antithrombotic medication. During a median follow-up of 2.0 years (interquartile range, 1.0–3.0), 40 children had a recurrent AIS, and none had a hemorrhagic stroke. The cumulative stroke recurrence rate was 6.8% (95% confidence interval, 4.6%–10%) at 1 month and 12% (8.5%–15%) at 1 year. The sole predictor of recurrence was the presence of an arteriopathy, which increased the risk of recurrence 5-fold when compared with an idiopathic AIS (hazard ratio, 5.0; 95% confidence interval, 1.8–14). The 1-year recurrence rate was 32% (95% confidence interval, 18%–51%) for moyamoya, 25% (12%–48%) for transient cerebral arteriopathy, and 19% (8.5%–40%) for arterial dissection.

Conclusions—
Children with AIS, particularly those with arteriopathy, remain at high risk for recurrent AIS despite increased utilization of antithrombotic agents. Therapies directed at the arteriopathies themselves are needed.
Piriqueta pampeana, a new species of Turneraceae (Passifloraceae s.l.) from Rio Grande do Sul, Brazil
Authors: Cabreira Thaíssa Nunes , Facco Marlon Garlet , Miotto Silvia Teresinha Sfoggia 
Published: November 2015

Piriqueta pampeana, a new species of Turneraceae, is described and illustrated here. The species occurs in the municipalities of Alegrete, Maçambará, Manoel Viana and São Francisco de Assis, in the western region of Rio Grande do Sul state, Brazil. It resembles Piriqueta suborbicularis and Piriqueta taubatensis, but can be distinguished by the presence of a pair of discoid basilaminar nectaries, a pair of petiolar nectaries and small nectaries distributed along the leaf margin, sepals with acute apex and a yellow spot at the base of the petals. Due to the intense environmental degradation of its habitat, and according to IUCN guidelines, we ranked the species as “Endangered” (EN).
Climatology of Lake-Effect Precipitation Events over Lake Tahoe and Pyramid Lake
Authors: Laird Neil , Bentley Alicia M. , Ganetis Sara A. , Stieneke Andrew , Tushaus Samantha A. 
Published: November 2015

AbstractThe frequency, timing, and environmental conditions of lake-effect (LE) precipitation over Lake Tahoe and Pyramid Lake in northern California and western Nevada were examined for the 14 winters (September–March) from 1996/97 through 2009/10. Weather Surveillance Radar-1988 Doppler (WSR-88D) data from Reno, Nevada (KRGX), were used to identify 62 LE events. LE precipitation occurred as single bands extending downwind from overlake areas, and as isolated regions of overlake precipitation with little or no extension over land. Mesoscale vortices were also identified during both Lake Tahoe and Pyramid Lake LE events. An average of 4.4 LE events occurred each winter in the Lake Tahoe and Pyramid Lake region, with events occurring most frequently in October. LE events had an average duration of 6.3 h, approximately half the duration of LE events observed over Lake Champlain, the New York State Finger Lakes, or the Great Salt Lake. The observed conditions during LE events in the Lake Tahoe and Pyramid Lake region typically had 1) mean surface air temperatures below freezing, 2) mean surface wind speeds of <2.0 m s−1 (notably weaker than during lake effect in other areas), 3) a mean lake–air temperature difference of 11.5°C, and 4) a mean lake–700-hPa temperature difference of 20.9°C.
Further Insights on the Influence of the Indian Ocean Dipole on the Following Year’s ENSO from Observations and CMIP5 Models
Authors: Jourdain Nicolas C. , Lengaigne Matthieu , Vialard Jérome , Izumo Takeshi , Gupta Alexander Sen 
Published: November 2015

Abstract
Recent observational studies have suggested that negative and positive Indian Ocean dipole (IOD) events (nIOD and pIOD, respectively) favor a transition toward, respectively, El Niño and La Niña events one year later. These statistical inferences are however limited by the length and uncertainties in the observational records. This paper compares observational datasets with twenty-one 155-yr historical simulations from phase 5 of CMIP (CMIP5) to assess IOD and El Niño–Southern Oscillation (ENSO) properties along with their synchronous and delayed relationships. In the observations and most CMIP5 models, it is shown that El Niños tend to be followed by La Niñas but not the opposite, that pIODs co-occur more frequently with El Niños than nIODs with La Niñas, that nIODs tend to be followed by El Niños one year later less frequently than pIODs by La Niñas, and that including an IOD index in a linear prediction based on the Pacific warm water volume improves ENSO peak hindcasts at 14 months lead. The IOD–ENSO delayed relationship partly results from a combination of ENSO intrinsic properties (e.g., the tendency for El Niños to be followed by La Niñas) and from the synchronous IOD–ENSO relationship. The results, however, reveal that this is not sufficient to explain the high prevalence of pIOD–Niña transitions in the observations and 75% of the CMIP5 models, and of nIOD–Niño transitions in 60% of CMIP5 models. This suggests that the tendency of IOD to lead ENSO by one year should be explained by a physical mechanism that, however, remains elusive in the CMIP5 models. The ability of many CMIP5 models to reproduce the delayed influence of the IOD on ENSO is nonetheless a strong incentive to explore extended-range dynamical forecasts of ENSO.
Implications of the Observed Relationship between Tropical Cyclone Size and Intensity over the Western North Pacific
Authors: Wu Liguang , Tian Wei , Liu Qingyuan , Cao Jian , Knaff John A. 
Published: November 2015

Abstract
Tropical cyclone (TC) size, usually measured with the radius of gale force wind (34 kt or 17 m s−1), is an important parameter for estimating TC risks such as wind damage, rainfall distribution, and storm surge. Previous studies have reported that there is a very weak relationship between TC size and TC intensity. A close examination presented here using satellite-based wind analyses suggests that the relationship between TC size and intensity is nonlinear. TC size generally increases with increasing TC maximum sustained wind before a maximum of 2.50° latitude at an intensity of 103 kt or 53.0 m s−1 and then slowly decreases as the TC intensity further increases. The observed relationship between TC size and intensity is compared to the relationships produced by an 11-yr seasonal numerical simulation of TC activity. The numerical simulations were able to produce neither the observed maximum sustained winds nor the observed nonlinear relationship between TC size and intensity. This finding suggests that TC size cannot reasonably be simulated with 9-km horizontal resolution and increased resolution is needed to study TC size variations using numerical simulations.
Application of the WRF-LETKF Data Assimilation System over Southern South America: Sensitivity to Model Physics
Authors: Dillon María E. , Skabar Yanina García , Ruiz Juan , Kalnay Eugenia , Collini Estela A. , Echevarría Pablo , Saucedo Marcos , Miyoshi Takemasa , Kunii Masaru 
Published: November 2015

Abstract
Improving the initial conditions of short-range numerical weather prediction (NWP) models is one of the main goals of the meteorological community. Development of data assimilation and ensemble forecast systems is essential in any national weather service (NWS). In this sense, the local ensemble transform Kalman filter (LETKF) is a methodology that can satisfy both requirements in an efficient manner. The Weather Research and Forecasting (WRF) Model coupled with the LETKF, developed at the University of Maryland, College Park, have been implemented experimentally at the NWS of Argentina [Servicio Meteorológico Nacional (SMN)], but at a somewhat lower resolution (40 km) than the operational Global Forecast System (GFS) at that time (27 km). The purpose of this work is not to show that the system presented herein is better than the higher-resolution GFS, but that its performance is reasonably comparable, and to provide the basis for a continued improved development of an independent regional data assimilation and forecasting system. The WRF-LETKF system is tested during the spring of 2012, using the prepared or quality controlled data in Binary Universal Form for Representation of Meteorological Data (PREPBUFR) observations from the National Centers for Environmental Prediction (NCEP) and lateral boundary conditions from the GFS. To assess the effect of model error, a single-model LETKF system (LETKF-single) is compared with a multischeme implementation (LETKF-multi), which uses different boundary layer and cumulus convection schemes for the generation of the ensemble of forecasts. The performance of both experiments during the test period shows that the LETKF-multi usually outperforms the LETKF-single, evidencing the advantages of the use of the multischeme approach. Both data assimilation systems are slightly worse than the GFS in terms of the synoptic environment representation, as could be expected given their lower resolution. Results from a case study of a strong convective system suggest that the LETKF-multi improves the location of the most intense area of precipitation with respect to the LETKF-single, although both systems show an underestimation of the total accumulated precipitation. These preliminary results encourage continuing the development of an operational data assimilation system based on WRF-LETKF at the SMN.
Cloud-Resolving Typhoon Rainfall Ensemble Forecasts for Taiwan with Large Domain and Extended Range through Time-Lagged Approach
Authors: Wang Chung-Chieh , Huang Shin-Yi , Chen Shin-Hau , Chang Chih-Sheng , Tsuboki Kazuhisa 
Published: November 2015

Abstract
In this study, the performance of a new ensemble quantitative precipitation forecast (QPF) system for Taiwan, with a cloud-resolving grid spacing of 2.5 km, a large domain of 1860 km × 1360 km, and an extended range of 8 days, is evaluated for six typhoons during 2012–13. Obtaining the probability (ensemble) information through a time-lagged approach, this system combines the strengths of high resolution (for QPF) and longer lead time (for hazard preparation) in an innovative way. For the six typhoons, in addition to short ranges (≤3 days), the system produced a decent QPF at a longest range up to days 8, 4, 6, 3, 6, and 7, providing greatly extended lead times, especially for slow-moving storms that pose higher threats. Moreover, since forecast uncertainty (reflected in the spread) is reduced with lead time, this system can provide a wide range of rainfall scenarios across Taiwan with longer lead times, each highly realistic for the associated track, allowing for advanced preparation for worst-case scenarios. Then, as the typhoon approaches and the predicted tracks converge, the government agencies can make adjustments toward the scenario of increasing likelihood. This strategy fits well with the conventional wisdom of “hoping for the best, but preparing for the worst” when facing natural hazards. Overall, the system presented herein compares favorably in usefulness to a typical 24-member ensemble (5-km grid size, 750 km × 900 km, 3-day forecasts) currently in operation using similar computational resources. Requiring about 1500 cores to execute four 8-day runs per day, it is not only powerful but also affordable and feasible.
Differences between Conservatives and Liberals in Information-Seeking Behavior and Perceived Risks Associated with Climate-Driven Changes to Local Forest Conditions
Authors: Smith Jordan W. , Bitsura-Meszaros Karly , Keane Rosemary 
Published: November 2015

Abstract
Ideological value sets have the potential to shape individuals’ preferences as well as their psychological and behavioral responses to new information. Being socially constructed, ideologies are likely to be formed and modified through the exchanges individuals have in their established information and communication networks. This study examined whether or not individuals’ political ideologies and their access to climate-related information are related to several key factors influencing their perceived capacity to adapt to climate-driven changes to local forest conditions. The key factors investigated include: perceived risk; the willingness to learn about potential impacts; the willingness to plan for variable climate futures; and a general perception of self-efficacy. Data come from a mail survey completed by 420 full-time residents living in three amenity-rich forest-related communities in western North Carolina (United States). The results suggest individuals’ political ideologies are related to some, but not all, of the information sources asked about. The results also suggest political ideologies are related to perceived risk, with conservatives perceiving climate-driven changes to local forest conditions as more severe relative to liberals. These findings have several implications regarding the effective dissemination of information related to how increasingly variable climate conditions may affect local forest conditions.
Potential Benefits of Combination Therapy as Primary Treatment for Sudden Sensorineural Hearing Loss
Authors: Lee Jong Bin , Choi Seong Jun 
Published: November 2015

ObjectiveWe analyzed the effectiveness of combination therapy (CT) for idiopathic sudden sensorineural hearing loss (ISSNHL) and the utility of intratympanic dexamethasone injection (ITDI) reapplication as salvage treatment for ISSNHL refractory to CT.Study DesignCase series with chart review.SettingAcademic university hospital.Subjects and MethodsWe reviewed 229 patients with ISSNHL and divided these patients into 2 groups according to treatment: systemic steroid therapy (SST) and CT groups. The SST group received prednisolone therapy. The CT group also received ITDI daily. Patients who demonstrated no recovery (<10 dB) after initial treatment were defined as refractory and received salvage ITDI therapy: ITDI reapplication in the CT group and ITDI application in the SST group.ResultsHearing recovery rates were 77.8% (77/99) in the CT group and 60.8% (79/130) in the SST group. The difference was statistically significant (P =. 011). Initial pure‐tone audiometry and vertigo were affective factors on hearing recovery rates in the CT group. After salvage therapy, hearing improvement of 10 dB or greater was noted in 6 of the 22 (27.3%) patients in the CT group and 16 of the 51 (31.4%) patients in the SST group. The difference in efficacy of salvage therapy between the CT and SST groups was simply not significant (P =. 612).ConclusionsCombination therapy was more effective for ISSNHL in achieving hearing gain than SST alone. Furthermore, ITDI reapplication for ISSNHL refractory to CT was as effective as salvage ITDI for ISSNHL refractory to SST.
Quality Improvement in Otolaryngology Residency
Authors: Bowe Sarah N. 
Published: November 2015

ObjectivesThe Clinical Learning Environment Review focuses on the responsibility of the sponsoring institution for quality and patient safety. Very little information is known regarding the status of quality improvement (QI) education during otolaryngology training. The purpose of this survey is to evaluate the extent of resident and faculty participation in QI and identify opportunities for both resident curriculum and faculty development.Study DesignCross‐sectional surveySubjects and MethodsA 15‐item survey was distributed to all 106 otolaryngology program directors. The survey was developed after an informal review of the literature regarding education in QI and patient safety. Questions were directed at the format and content of the QI curriculum, as well as barriers to implementation.ResultsThere was a 39% response rate. Ninety percent of responding program directors considered education in QI important or very important to a resident’s future success. Only 23% of responding programs contained an educational curriculum in QI, and only 33% monitored residents’ individual outcome measures. Barriers to implementation of a QI program included inadequate number of faculty with expertise in QI (75%) and competing resident educational demands (90%). Every program director considered morbidity and mortality conferences as an integral component in QI education.ConclusionsProgram directors recognize the importance of QI in otolaryngology practice. Unfortunately, this survey identifies a distinct lack of resources in support of these educational goals. The results highlight the need to generate a comprehensive and stepwise approach to QI for faculty development and resident instruction.
Comparative phylogeography of endemic Azorean arthropods
Authors: Parmakelis Aristeidis , Rigal François , Mourikis Thanos , Balanika Katerina , Terzopoulou Sofia , Rego Carla , Amorim Isabel R. , Crespo Luís , Pereira Fernando , Triantis Kostas A. , Whittaker Robert J. , Borges Paulo A. V. 
Published: November 2015

AbstractBackgroundFor a remote oceanic archipelago of up to 8 Myr age, the Azores have a comparatively low level of endemism. We present an analysis of phylogeographic patterns of endemic Azorean island arthropods aimed at testing patterns of diversification in relation to the ontogeny of the archipelago, in order to distinguish between alternative models of evolutionary dynamics on islands. We collected individuals of six species (representing Araneae, Hemiptera and Coleoptera) from 16 forest fragments from 7 islands. Using three mtDNA markers, we analysed the distribution of genetic diversity within and between islands, inferred the differentiation time-frames and investigated the inter-island migration routes and colonization patterns.ResultsEach species exhibited very low levels of mtDNA divergence, both within and between islands. The two oldest islands were not strongly involved in the diffusion of genetic diversity within the archipelago. The most haplotype-rich islands varied according to species but the younger, central islands contributed the most to haplotype diversity. Colonization events both in concordance with and in contradiction to an inter-island progression rule were inferred, while a non-intuitive pattern of colonization from western to eastern islands was also inferred.ConclusionsThe geological development of the Azores has followed a less tidy progression compared to classic hotspot archipelagos, and this is reflected in our findings. The study species appear to have been differentiating within the Azores for <2 Myr, a fraction of the apparent life span of the archipelago, which may indicate that extinction events linked to active volcanism have played an important role. Assuming that after each extinction event, colonization was initiated from a nearby island hosting derived haplotypes, the apparent age of species diversification in the archipelago would be moved closer to the present after each extinction–recolonization cycle. Exploiting these ideas, we propose a general model for future testing.
Processing insect abundance: trading and fishing of zazamushi in Central Japan (Nagano Prefecture, Honshū Island)
Authors: Césard Nicolas , Komatsu Seiji , Iwata Akihisa 
Published: November 2015

Abstract
Background
This article presents the links between technique, commerce and consumption in fishing for zazamushi, a mixture of aquatic insect larvae sold as food souvenirs in Japan. Since zazamushi are mainly collected for economic reasons, we suggest that demand for them has incited technical development among collectors in order to fish more insects.

Methods
Several fishermen and traders were interviewed in semi-directed interviews about their practices and knowledge. To understand the passage from a faunal composition to a commercial composition, our research follows a fishing session closely, as well as the selection of insects that follows it. The insects collected were separated from inanimate matter, then identified, counted and weighed at each stage of the process.

Results
Our results suggest that the current technique corresponds to an evolution in subsistence and recreational collecting towards a more systematic fishing of the insects, the aim of which is commercial. In their response to trade issues, the collectors have moved away from the banks to fish the insects in the river current, thus increasing the amount of one species captured compared to another. Although the technique is efficient (and similar to other harvesting techniques), it requires the thorough sorting of organic debris and insects (in our example, the catch contains approximately 78 % of inanimate matter and 22 % of insects, of which 3.29 % are retained for consumption, i.e., less than 2 out of 100 insects). The selection of insects to be consumed takes place mainly during cleaning. This stage depends on traders and reflects the different compositions sold as souvenirs.

Conclusions
Our research shows that the consumption of insects is not explained just by ecological factors that are favourable or unfavourable, but also by technological and economic factors related to their commerce. It suggests that the traders have gradually established the insects that are currently sold as zazamushi and that this commercial development may have had an influence on the preference for insects consumed. It also shows that the cleaning of the insects constitutes an important stage prior to their consumption, one that should not be underestimated.