bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tracking the enzyme-response mechanism of tannic acid-embedded chitosan/γ-polyglutamic acid hydrogel
Authors: Han Zhenxing , Wang Mengmeng , Hu Ziwei , Wang Yu , Tong Jie , Zhao Xiaofeng , Yue Wenjin , Nie Guangjun 
Published: July 2024

AbstractThe design of enzyme-response hydrogels has attracted increasing interest in cell therapy, biomedical research, and tissue engineering. Their rational design usually depends on the enzyme-response mechanism and have focused on behavior improvement, drug delivery, and state transition of hydrogels. However, no enzyme-response mechanism has yet been systematically investigated. Here, we construct a tunable platform of tannic acid-embedded chitosan/γ-polyglutamic acid hydrogel to study the enzyme-response mechanism. We track the roles of gallic acid hydrolyzed from tannic acid in altering the structure and properties of the hydrogel to get insights into the mechanism. The gallic acid inside the hydrogel enhances hydrogel crosslinking, increasing the mechanical properties and pH sensitivity but reducing thickness, porosity, and swelling behavior. The gallic acid outside the hydrogel increases the positive potential and superficial hydrophobicity of the hydrogel. These findings will aid the rational design of other enzyme-response hydrogels in more extensive self-adaptive fields.
Negative photo conductivity triggered with visible light in wide bandgap oxide-based optoelectronic crossbar memristive array for photograph sensing and neuromorphic computing applications
Authors: Kumar Dayanand , Li Hanrui , Singh Amit , Rajbhar Manoj Kumar , Syed Abdul Momin , Lee Hoonkyung , El-Atab Nazek 
Published: July 2024

AbstractPhotoresponsivity studies of wide-bandgap oxide-based devices have emerged as a vibrant and popular research area. Researchers have explored various material systems in their quest to develop devices capable of responding to illumination. In this study, we engineered a mature wide-bandgap oxide-based bilayer heterostructure synaptic memristor to emulate the human brain for applications in neuromorphic computing and photograph sensing. The device exhibits advanced electric and electrophotonic synaptic functions, such as long-term potentiation (LTP), long-term depression (LTD), and paired-pulse facilitation (PPF), by applying successive electric and photonic pulses. Moreover, the device exhibits exceptional electrical SET and photonic RESET endurance, maintaining its stability for a minimum of 1200 cycles without any degradation. Density functional theory calculations of the band structures provide insights into the conduction mechanism of the device. Based on this memristor array, we developed an autoencoder and convolutional neural network for noise reduction and image recognition tasks, which achieves a peak signal-to-noise ratio of 562 and high accuracy of 84.23%, while consuming lower energy by four orders of magnitude compared with the Tesla P40 GPU. This groundbreaking research not only opens doors for the integration of our device into image processing but also represents a significant advancement in the realm of in-memory computing and photograph-sensing features in a single cell.
Improving the quantum yield of luminescence for three-coordinated gold(i) TADF emitters by exploiting inversion symmetry and using perhaloaryl ligands
Authors: Soldevilla Inés , El-Hachimi Abdel Ghafour , Ramazanov Ruslan , Valiev Rashid R. , Olmos M. Elena , Monge Miguel , Sundholm Dage , Rodríguez-Castillo María , López-de-Luzuriaga José M. 
Published: July 2024

New perhalophenyl gold(i)–tetraphosphino complexes are designed as highly efficient luminescent molecules. The electronegativity of the aryl groups and the symmetry of the molecules enable the formation of species with improved quantum yields at RT.
The Effect of Different Sensory Perturbations on Postural Control and Fall Risk in Benign Paroxysmal Positional Vertigo Patients
Authors: Şahin Esma Temiçin , Orhan Emre , Tutar Volkan , Tutar Hakan , Gündüz Bülent 
Published: July 2024

Background:
Benign paroxysmal positional vertigo (BPPV) patients may experience balance problems in various environmental conditions other than positional dizziness. Therefore, there is a need to investigate the postural control abilities and the ability to use sensory inputs in BPPV patients in different conditions.

Objective:
The aim of this study was to examine the postural control performance of middle-aged adult BPPV patients in easy and difficult balance tasks, the effect of vestibular stimulation on the maintenance of balance, and the risk of falling, by posturographic evaluation in various conditions.

Method:
A total of 26 patients diagnosed with posterior canal BPPV and 26 controls were included in the study. Sensory Organization Test (SOT), Vestibular Stimulation Test (VST), and fall risk assessment (FRA) were applied to the participants, respectively.

Results:

Significant difference was observed in SOT medio-lateral (ML) plane in Conditions 2 and 5 (
p
< .05). A significant difference was observed in the vestibular score in the SOT ML plane. No significant difference was observed in VST test scores (
p
> .05). In the FRA test, a significant difference was observed in the energy and gain parameters in the anterio-posterior plane (
p
< .05).

Conclusions:
The current study examined postural control abilities of patients with BPPV in extensive external conditions and in both planes, using various sensory perturbations and stimulation. It was thought that while BPPV patients were in the active phase of the disease, their postural control skills in the ML plane decreased and they might be at risk of falling.
A case of the effective inhalation of nitric oxide therapy for caused severe pulmonary hypertension with protamine neutralization of systemic heparinization during totally endoscopic minimally invasive cardiac surgery
Authors: Takeichi Tomohisa , Morimoto Yoshihisa , Yamada Akitoshi , Tanaka Takanori 
Published: July 2024

Severe pulmonary vasoconstriction induced by protamine is a rare complication. We report a case of a 77-year-old male patient with a history of mitral valve plasty (MVP). He underwent redo MVP via right thoracotomy under the totally endoscopic procedure (MICS redo-MVP). Immediately after weaning cardiopulmonary bypass (CPB), protamine was administrated. 10 min later peak systolic pulmonary arterial pressure (sys PAP) rose to 62 mmHg, and 30 min later to 80 mmHg. Due to the negative impact of protamine administration, nitric oxide inhalation (iNO) therapy was started with a concentration of 20 ppm. 10 min after iNO therapy started, sys PAP decreased to 63 mmHg. After entering the intensive care unit (ICU), sys PAP decreased to 35 mmHg. Here, we present an effective iNO therapy case for pulmonary hypertension due to protamine and the patient had a good postoperative recovery.
This study was approved by the Institutional Review Board at Kitaharima Medical Center (IRB-0602) with the waiver of informed consent.
Cardiopulmonary bypass in a pediatric patient with factor XII deficiency
Authors: Fenske Julie M. , Tinius Juliani Julie , Herrington Cynthia 
Published: July 2024

The safe use of cardiopulmonary bypass (CPB) relies upon the ability to administer, monitor, and reverse anticoagulation. Although rare, the factor XII deficient patient creates a challenge for the perfusionist due to resultant complications in monitoring anticoagulation. There have been proposed strategies to aid in monitoring anticoagulation in factor XII deficient patients, however, documentation of successful monitoring during CPB is infrequent. With the use of the Hemochron Signature Elite and ACT + cartridges, CPB in a factor XII deficient 8-month-old was completed with predictable and reliable anticoagulation monitoring. This case report explores the current suggestions for factor XII deficiency management with CPB.
Carbamylation is Instrumental in End-Stage Kidney Disease Coagulopathies: The Impact on von Willebrand Factor and Platelet Functionality
Authors: Babickova Janka , Kałucka Urszula , Kaminska Marta , Mydel Piotr , Sochaj-Grzegorczyk Alicja , Potempa Jan , Scavenius Carsten , Knoop Thomas , Marti Hans-Peter 
Published: July 2024

Background Chronic kidney disease (CKD) is a progressive, irreversible, and incurable condition characterized by high morbidity and mortality, affecting approximately one-tenth of the global population. Rise of urea-derived cyanate levels in CKD patients, severalfold higher in comparison to those found in healthy individuals, leads to an increased rate of carbamylation of lysine residues of proteins and peptides. This posttranslational modification plays an important role in the progression of kidney failure but also in the onset of CKD-related complications, including previously reported coagulopathies. In this study, we have explored the impact of carbamylation on the functionality of von Willebrand factor (vWF), a pivotal player in hemostasis, and its implications for platelet adhesion.
Materials and Methods We have explored carbamylated vWF's interactions with its partner proteins via ELISA. Mass spectrometry was employed to identify modified lysine residues. Blood platelets isolated from healthy donors were carbamylated, and their activation, binding to endothelium and thromboxane release were evaluated using flow cytometry, adhesion assays and ELISA, respectively.
Results Using mass spectrometry we detected the vWF's lysine residue smost susceptible to carbamylation. This modification has in turn affected vWF's interactions with its key binding partners: decreased binding to collagen types I/III but increased the affinity to factor FVIII, while its binding to fibrinogen remained unchanged. Carbamylation of vWF impeded vWF-blood platelet binding, but carbamylation of platelets led to their increased thrombin-dependent activation as observed by enhanced phosphatidylserine exposure, improved their binding to vascular endothelium, at the same time decreasing the production of the prothrombotic mediator, thromboxane A2.
Conclusion Our findings highlight the multifaceted impact of carbamylation on vWF and platelets, disturbing the delicate balance of coagulation cascade. These alterations could contribute to the complex hemostatic imbalance in ESKD, underscoring the need for further research to fully understand these mechanisms and their clinical implications.
Distal Radioulnar Joint Orientation and Lunate Morphology as Protective Factors of Symptomatic Idiopathic Ulnar Impaction Syndrome in Ulnar-Positive Variant Patients
Authors: Shin Seong Kee , Kim Ki Hong , Kim Kyu Jin 
Published: July 2024

Abstract
Background Ulnar-positive variance is widely recognized as a risk factor for idiopathic ulnar impaction syndrome (UIS). However, not all patients with ulnar-positive variance progress to symptomatic UIS. Other factors, such as the shape of the lunate or the distal radioulnar joint (DRUJ), may also play a role. This study aims to elucidate the relationship between the shape of the lunate and the structure of the DRUJ and idiopathic UIS.
Patients and Methods A cohort of 40 cases diagnosed with idiopathic UIS (UIS group) and 87 control subjects with ulnar-positive variance but without symptoms were compared. Lunate shape was assessed by measuring the lunate type and radiolunate angle (RLA), whereas DRUJ morphology was evaluated using the sigmoid notch angle, DRUJ subluxation ratio, and DRUJ inclination. Independent t-tests were conducted to analyze differences in radiographic metrics between the two groups, and logistic regression analyses were used to examine risk factors for idiopathic UIS. Receiver operating characteristic curves were utilized to determine the cutoff values for statistically significant variables.
Results Significant differences were observed between the two groups in terms of RLA, DRUJ subluxation ratio, and DRUJ inclination (p < 0.05). Logistic multiple regression analysis revealed a negative correlation between idiopathic UIS occurrence and both RLA (odds ratio [OR]: 0.92; 95% confidence interval [CI]: 0.87–0.96; p < 0.001) and the DRUJ subluxation ratio (OR: 0.01; 95% CI: 0–0.07; p = 0.002). Conversely, a positive correlation was found between UIS occurrence and DRUJ inclination (OR: 1.06; 95% CI: 1.01–1.12; p = 0.021).
Conclusion In patients with ulnar-positive variance, the incidence of symptomatic UIS decreases when the lunate extends more relative to the radius and when the DRUJ subluxation ratio increases or DRUJ inclination decreases.
Level of Evidence Level III, case–control study.
Analyzing modality-mediated ideology in translated Chinese political discourses: an ideological square model approach
Authors: Lijuan Du , Afzaal Muhammad 
Published: July 2024

AbstractThis study investigates the correlation between textual ideology and the English translations of political discourse. It focuses on how the translation shifts of modality relate to the socio-political and socio-cultural context of Chinese political discourse using the modality system of Systemic Functional Linguistics (SFL) as the theoretical framework. Three main types of translation shifts between should and will, and their corresponding items are identified. First, the addition of modal items should and will in the TTs; second, downgrading the modality value of Chinese modality items to the lower-valued should and will in the TTs; third, upgrading the modality value of Chinese modality items to a higher-valued will in the TTs. The study attributes these findings to van Dijk’s ideological square model and the variable of tenor (the social distance between the speaker and the addresses and the social distance between the official translators of Chinese political discourse and the international audience.
Experimental study of drag characteristics and dust removal performance of a hybrid wet-filter precipitator
Authors: Yi Hang , Yang Zifeng , Chang Deqiang , Tian Xinjiao , Liu Jingxian 
Published: July 2024

With their advantages of high dust removal efficiency and low drag characteristics, hybrid wet-filter precipitators have great potential for dust control in coal mines, but the underlying mechanisms are not well understood. In this study, to help fill this knowledge gap, a hybrid wet-filter precipitator consisting of a 40-layer metal filter and a defogger device is designed and a prototype is constructed. Experiments are conducted to investigate its drag characteristics under wind velocities from 0.85 to 5.68 m/s and its dust removal performance under wind velocities of 2 and 4 m/s. On the basis of results with the initial design, which show that the dust removal efficiency does not meet the target value of 99%, two rounds of improvement are implemented to enhance the dust removal efficiency. Results show that the defogger device contributes ∼80% of the total drag. The drag from the metal filters is found to increase by over 80% on average after sampling, since some of dust particles are left on the filters, decreasing their porosity. The installation of two-layer air filters on the leeside of the metal filter unit is found to increase the efficiency to 99.89% and 99.80% under wind velocities of 2 and 4 m/s, respectively, although this is at the cost of increased drags. Additionally, it is found that the replacement of the defogger by a 20-layer metal filter is not desirable, since this increases the downstream air humidity to more than 100%, which can cause damage to the centrifugal blower system. Therefore, new designs for the defogger device need to be examined in future studies.
Optical bias and cryogenic laser readout of a multipixel superconducting nanowire single photon detector
Authors: Thiele Frederik , Lamberty Niklas , Hummel Thomas , Bartley Tim 
Published: July 2024

Cryogenic opto-electronic interconnects are gaining increasing interest as a means to control and readout cryogenic electronic components. The challenge is to achieve sufficient signal integrity with low heat load processing. In this context, we demonstrate the opto-electronic bias and readout of a commercial four-pixel superconducting nanowire single-photon detector array using a cryogenic photodiode and laser. We show that this approach has a similar system detection efficiency to a conventional bias. Furthermore, multi-pixel detection events are faithfully converted between the optical and electrical domains, which allows reliable extraction of amplitude multiplexed photon statistics. Our device has a latent heat load of 2.6 mW, maintains a signal rise time of 3 ns, and operates in free-running (self-resetting) mode at a repetition rate of 600 kHz. This demonstrates the potential of high-bandwidth, low noise, and low heat load opto-electronic interconnects for scalable cryogenic signal processing and transmission.
FeNNol: An efficient and flexible library for building force-field-enhanced neural network potentials
Authors: Plé Thomas , Adjoua Olivier , Lagardère Louis , Piquemal Jean-Philip 
Published: July 2024

Neural network interatomic potentials (NNPs) have recently proven to be powerful tools to accurately model complex molecular systems while bypassing the high numerical cost of ab initio molecular dynamics simulations. In recent years, numerous advances in model architectures as well as the development of hybrid models combining machine-learning (ML) with more traditional, physically motivated, force-field interactions have considerably increased the design space of ML potentials. In this paper, we present FeNNol, a new library for building, training, and running force-field-enhanced neural network potentials. It provides a flexible and modular system for building hybrid models, allowing us to easily combine state-of-the-art embeddings with ML-parameterized physical interaction terms without the need for explicit programming. Furthermore, FeNNol leverages the automatic differentiation and just-in-time compilation features of the Jax Python library to enable fast evaluation of NNPs, shrinking the performance gap between ML potentials and standard force-fields. This is demonstrated with the popular ANI-2x model reaching simulation speeds nearly on par with the AMOEBA polarizable force-field on commodity GPUs (graphics processing units). We hope that FeNNol will facilitate the development and application of new hybrid NNP architectures for a wide range of molecular simulation problems.
Numerical simulation of a nebulizer with multiple orifices
Authors: Chen (陈泽譞) Zexuan , Butan Daniela , Clifford Seamus , Greaney Russell , Cunningham Sean , Griffin Philip 
Published: July 2024

Abstract
A vibrating mesh nebulizer is a medical device that can break liquid medication into an aerosol of tiny droplets so that patients can inhale them to treat diseases. The volumetric flow rate of this kind of nebulizer is determined by many factors, including the orifice geometry, the vibration amplitude and the vibration mode shape. Thus, many experiments were designed to assess the effects of these different variables on flow rate and to find the optimal set of device parameters that maximizes the flow rate. However, it can be very expensive to perform such physical experimentation with physical prototypes, which needs different orifice geometries to be fabricated for different test regimes. The orifice sizes are microscopic with diameters typically between 3 µm and 5 µm, thus, they are difficult to be fabricated with the exact shape and diameter that are required. Therefore, virtual prototyping by means of numerical simulation models are required as the orifice geometries and other factors can be easily changed in the simulation models. This study aims to provide a numerical simulation model that is experimentally validated. By comparing the simulated flow rates with the experimentally obtained flow rates, and the simulated droplet diameters with the experimentally obtained droplet diameters, it was found that the errors are all less than 10

%

which demonstrates this numerical simulation model is adequately validated by experiment. Thus, instead of carrying out expensive experiments, this simulation model can be used for predicting the volumetric flow rates for different prescribed orifice geometries. Furthermore, this paper also simulates the effects of viscosity and surface tension on the flow rate, where either viscosity or surface tension increases, the flow rate will decrease.
X-ray spectrometry for calculating conversion coefficients from air kerma to operational quantities in radiation protection
Authors: Plagnard Johann , Lefèvre Jérémie 
Published: July 2024

Abstract
This study explores the conversion coefficients from air kerma to operational quantities for radiation protection, using x-ray spectrometry for the narrow-beam qualities below 300 keV as defined by ISO 4037-1. By employing custom spectral correction algorithms combined with modern cadmium telluride (CdTe) semiconductor detectors, we effectively corrected spectral distortions caused by detection processes, ensuring more reliable measurements. These measurements are crucial for meeting radiation protection standards. The study also analyses the sources of uncertainty associated with the determination of conversion coefficients, thereby providing improved accuracy and reproducibility in photon dosimetry.
Study on the interaction mechanism of laser-generated Rayleigh waves and subsurface inclined cracks
Authors: Wang Chuanyong , Zhang Fumin , Chen Yuanliu , Wang Wen , Wang Yun , Lu Keqing , Ding Yuanping , Shen Yinliang , Ju Bing-Feng 
Published: July 2024

Abstract
In this paper, the finite element method was used to study the reflected and transmitted waves of laser-generated Rayleigh waves from subsurface inclined cracks, the propagation paths and mode conversion mechanisms of different characteristic waves are determined. The Rayleigh wave will interact with the crack top tip and propagate back and forth along the crack surface, and be converted to shear waves at the crack top tip. The shear waves will mode-convert to Rayleigh waves at the free surface when the incidence angle of the shear wave is larger than 60°. Moreover, for the Rayleigh wave interacting with the crack bottom tip, when the crack inclined angle is less than 60°, some Rayleigh waves will travel along the crack surface to the crack top tip. When the crack inclination angle is greater than 60°, in addition to the Rayleigh waves propagating upwards along the crack surface, some Rayleigh waves convert to shear waves at the crack bottom tip and then incident on the free surface of the workpiece. Experiments were carried out to validate some of the Rayleigh wave propagation paths. The experimental results matched the theoretical arrival time well, thus verifying the reliability of the analytical wave path. The results are helpful for the quantitative detection of subsurface inclined cracks using laser ultrasonic techniques.