bluuebunny/crossref_metadata_2025_split huggingface dataset:
Versatile Pd‐Catalyzed CH Oxidative Cyclization of Homoallylhydrazones to Pyrazolines and Tetrahydropyridazines
Authors: Mboyi Cleve Dionel , Abdellah Ibrahim , Duhayon Carine , Canac Yves , Chauvin Remi 
Published: July 2013

AbstractPd‐catalyzed 5‐exo‐trig or 6‐endo‐trig CH oxidative cyclization of C‐homoallyl‐N‐sulfonylhydrazones to 5‐vinylpyrazolines or 6‐methylidene‐1,4,5,6‐tetrahydropyridazines, respectively, is shown to be controlled in a highly selective manner by the ionic character of the PdII catalytic center. This character is ultimately defined by the nature of the X ligand in the PdX2 salt serving as an in situ precursor of the active catalytic species involving BIPHIMIP {2‐(diphenylphosphino)‐1‐[2‐(diphenylphosphino)phenyl]‐1H‐imidazole} as an optimal spectator diphosphine ligand for both processes. Whereas acetates (X=OAc) favor the 6‐endo process, noncoordinating anions such as tosylates and triflates (X=OTs, OTf) favor the 5‐exo process.
How Cations Change Peptide Structure
Authors: Baldauf Carsten , Pagel Kevin , Warnke Stephan , von Helden Gert , Koksch Beate , Blum Volker , Scheffler Matthias 
Published: July 2013

AbstractSpecific interactions between cations and proteins have a strong impact on peptide and protein structure. Herein, we shed light on the nature of the underlying interactions, especially regarding effects on the polyamide backbone structure. This was done by comparing the conformational ensembles of model peptides in isolation and in the presence of either Li+ or Na+ by using state‐of‐the‐art density‐functional theory (including van der Waals effects) and gas‐phase infrared spectroscopy. These monovalent cations have a drastic effect on the local backbone conformation of turn‐forming peptides, by disruption of the hydrogen‐bonding networks, thus resulting in severe distortion of the backbone conformations. In fact, Li+ and Na+ can even have different conformational effects on the same peptide. We also assess the predictive power of current approximate density functionals for peptide–cation systems and compare to results with those of established protein force fields as well as high‐level quantum chemistry calculations (CCSD(T)).
Self‐Aggregated Dinuclear Lanthanide(III) Complexes as Potential Bimodal Probes for Magnetic Resonance and Optical Imaging
Authors: Regueiro‐Figueroa Martín , Nonat Aline , Rolla Gabriele A. , Esteban‐Gómez David , de Blas Andrés , Rodríguez‐Blas Teresa , Charbonnière Loïc J. , Botta Mauro , Platas‐Iglesias Carlos 
Published: July 2013

AbstractHomodinuclear lanthanide complexes (Ln=La, Eu, Gd, Tb, Yb and Lu) derived from a bis‐macrocyclic ligand featuring two 2,2′,2′′‐(1,4,7,10‐tetraazacyclododecane‐1,4,7‐triyl)triacetic acid chelating sites linked by a 2,6‐bis(pyrazol‐1‐yl)pyridine spacer (H2L3) were prepared and characterized. Luminescence lifetime measurements recorded on solutions of the EuIII and TbIII complexes indicate the presence of one inner‐sphere water molecule coordinated to each metal ion in these complexes. The overall luminescence quantum yields were determined (ϕ=0.01 for [Eu2(L3)] and 0.50 for [Tb2(L3)] in 0.01 M TRIS/HCl, pH 7.4; TRIS=tris(hydroxymethyl)aminomethane), pointing to an effective sensitization of the metal ion by the bispyrazolylpyridyl unit of the ligand, especially with Tb. The nuclear magnetic relaxation dispersion (NMRD) profiles recorded for [Gd2(L3)] are characteristic of slowly tumbling systems, showing a low‐field plateau and a broad maximum around 30 MHz. This suggests the occurrence of aggregation of the complexes giving rise to slowly rotating species. A similar behavior is observed for the analogous GdIII complex containing a 4,4′‐dimethyl‐2,2′‐bipyridyl spacer ([Gd2(L1)]). The relaxivity of [Gd2(L3)] recorded at 0.5 T and 298 K (pH 6.9) amounts to 13.7 mM−1 s−1. The formation of aggregates has been confirmed by dynamic light scattering (DLS) experiments, which provided mean particle sizes of 114 and 38 nm for [Gd2(L1)] and [Gd2(L3)], respectively. TEM images of [Gd2(L3)] indicate the formation of nearly spherical nanosized aggregates with a mean diameter of about 41 nm, together with some nonspherical particles with larger size.
Base‐Dependent Stereodivergent Intramolecular Aza‐Michael Reaction: Asymmetric Synthesis of 1,3‐Disubstituted Isoindolines
Authors: Fustero Santos , Herrera Lidia , Lázaro Ruben , Rodríguez Elsa , Maestro Miguel A. , Mateu Natalia , Barrio Pablo 
Published: July 2013

AbstractThe nucleophilic addition (AN) / intramolecular aza‐Michael reaction (IMAMR) process on Ellman’s tert‐butylsulfinyl imines, bearing a Michael acceptor in the ortho position, is studied. This reaction affords 1,3‐disubstituted isoindolines with a wide range of substituents in good yields and diastereoselectivities. Interestingly, careful choice of the base for the aza‐Michael step allows either the cis or the trans diastereoisomers to be exclusively obtained. This stereodivergent cyclization has enabled the synthesis of C2‐symmetric bisacetate‐substituted isoindolines. In addition, bisacetate isoindolines bearing two well‐differentiated ester moieties are also noteworthy because they may allow for the orthogonal synthesis of β,β′‐dipeptides using a single nitrogen atom as a linchpin.
Diamond Nanoelectrode Arrays for the Detection of Surface Sensitive Adsorption
Authors: Hees Jakob , Hoffmann René , Yang Nianjun , Nebel Christoph E. 
Published: July 2013

AbstractNanocrystalline diamond nanoelectrode arrays (NEAs) have been applied to investigate surface‐sensitive adsorption phenomena at the diamond–liquid interface. The adsorption of neutral methyl viologen (MV0) was used as a model system. The adsorption of MV0 was examined on hydrogen‐ and oxygen‐terminated surfaces. On the hydrogenated nanoelectrode surface, a sharp anodic stripping peak was observed upon oxidation of MV0, revealing strong adsorption of MV0. In contrast, a sigmoidal voltammogram was recorded with an oxygenated electrode surface, indicating there was no MV0 adsorption. The changes in the shapes of these voltammograms are due to the drastic changes that occur in the diffusion profiles during the transition. The diffusion profile changes from hemispherical diffusion on oxygen‐terminated surfaces to thin‐layer electrochemistry upon adsorption on hydrogen‐terminated surfaces. Different types and concentrations of buffer solutions were then used to vary the interaction of MV0 with diamond NEAs. The results suggest that the adsorption of MV0 on hydrogen‐terminated diamond NEAs is controlled by hydrophobic interactions. Therefore, diamond NEAs are ideal for the study of adsorption phenomena at the liquid–solid interface with voltammetry.
More than Meets the Eye: Conformational Switching of a Stacked Dialkoxynaphthalene–Naphthalenetetracarboxylic diimide (DAN–NDI) Foldamer to an NDI–NDI Fibril Aggregate
Authors: Peebles Cameron , Piland Rebecca , Iverson Brent L. 
Published: July 2013

AbstractThe thermally induced conformational switching of a stacked dialkxoynaphthalene–naphthalenetetracarboxylic diimide (DAN–NDI) amphiphilic foldamer to an NDI–NDI fibril aggregate is described. The aggregated fibril structures were explored by UV/Vis, circular dichroism (CD), atomic‐force microscopy (AFM), and TEM techniques. Our findings indicate that the aromatic DAN–NDI interactions of the original foldamer undergoes transformation to a fibrillar assembly with aromatic NDI–NDI stacked interactions. These structural insights could help inform new molecular designs and increase our understanding of fibrillar assembly and aggregation process in aqueous solution.
ChemInform Abstract: New Quinternary Selenides: Syntheses, Characterizations, and Electronic Structure Calculations.
Authors: Chung Ming‐Yan , Lee Chi‐Shen 
Published: July 2013

AbstractThe new compounds Sr2.63Y0.37Ge0.63Sb2.37 Se8 (I), Sr2.63La0.37Ge0.63Sb2.37 Se8 (II), Sr2.71La0.29Sn0.77Bi2.23 Se8 (III), Ba2.67La0.33Sn0.67Sb2.33 Se8 (IV), and Ba2.67La0.33Sn0.67Bi2.33 Se8 (V) are synthesized by solid state reactions of the elements (silica tubes, 1023 K, 1 d).
ChemInform Abstract: Large Scale Synthesis, Second‐Harmonic Generation, and Piezoelectric Properties of a Noncentrosymmetric Vanadium Phosphate, Li2VPO6.
Authors: Lee Eun Pyo , Lee Dong Woo , Cho Yoon‐Ho , Tran T. Thao , Halasyamani P. Shiv , Ok Kang Min 
Published: July 2013

AbstractPhase pure Li2VPO6 is prepared by solid state reaction of a stoichiometric mixture of Li2CO3, V2O5, and NH4H2PO4 (Al2O3 crucible, 580 °C, 36 h, cooling rate 10 °C/h).
ChemInform Abstract: A Facile Way to Synthesis KMgF3 and Its Luminescent Property with Eu Doping.
Authors: Wang Wei , Liu Xiaoyang , Zhang Jingchao , Ji Ying , Jiang Nan , Ma Bing , Wang Xiaofeng , Liu Li 
Published: July 2013

AbstractKMgF3 and KMgF3:Eu are prepared by molten salt synthesis from mixtures of KCl, MgCl2, Eu(NO3)3, and NH4HF2 as fluorine source and fluxing agent (autoclave, 180 °C, 24 h).
ChemInform Abstract: Synthesis and Magnetic Properties of a Quaternary Compound Ba3F2MnSe3 with One‐Dimensional Tetragonal Chain Structure.
Authors: Li Yuan‐Bing , Cheng Wen‐Dan , Zhang Wei‐Long , Luo Zhong‐Zhen 
Published: July 2013

AbstractThe title compound is synthesized by solid state reaction of BaF2, Mn, and Se in closed silica tubes at 1253 K for 72 h.
ChemInform Abstract: Pressure‐Induced Hydration and Insertion of CO2 into Ag‐Natrolite.
Authors: Lee Yongmoon , Seoung Donghoon , Jang Young‐Nam , Vogt Thomas , Lee Yongjae 
Published: July 2013

AbstractPressure‐induced hydration of Ag16Al16Si24O80 ·16H2O with water and CO2 as pressure‐transmitting medium is studied by in situ synchrotron powder XRD.
ChemInform Abstract: Photochemical Route for Accessing Amorphous Metal Oxide Materials for Water Oxidation Catalysis.
Authors: Smith Rodney D. L. , Prevot Mathieu S. , Fagan Randal D. , Zhang Zhipan , Sedach Pavel A. , Siu Man Kit Jack , Trudel Simon , Berlinguette Curtis P. 
Published: July 2013

AbstractPhotochemical metal‐organic deposition produces amorphous (mixed) metal oxide films, which show high electrocatalytic activity for the oxygen evolution reaction.
ChemInform Abstract: Synthesis and Characterization of Zinc Borophosphates with ANA‐Zeotype Framework by the Microwave Method.
Authors: Song Yu , Ding Ling , An Qingda , Zhai Shangru , Song Xiaowei 
Published: July 2013

AbstractLarge single crystals of (NH4)16 [Zn16B8P24O96] are synthesized by microwave‐assisted solvothermal reaction of ZnCl2, (NH4)2PO4, H3BO3, and ethylene glycol (autoclave, microwave irradiation, 200 °C, microwave power of 600 W for 5 min and 400 W microwave power for 2 h).
ChemInform Abstract: pH‐Dependent Assembly of 1D—2D Structures Based on Both {V10O28} and [NiMo6O24H6]4‐ Units: Synthesis, Structure and Magnetic Properties.
Authors: Yang Yanyan , Xu Lin , Li Fengyan , Qu Xiaoshu 
Published: July 2013

AbstractCompounds (IV) and (V) crystallize in the triclinic space group P$\bar 1$ with Z = 1 (single crystal XRD).
ChemInform Abstract: Sandwich‐Type Tungstoantimonates Decorated by the Heterometallic 3d—5p Clusters.
Authors: Duan Hui , Zhang Zhi‐Ming , Han Xin‐Bao , Chen Yi‐Zhen , Shen Jian‐Qiang , Wang Wei‐Peng , Zheng Xiao‐Tao , Zhou Huan‐Yu , Wang En‐Bo 
Published: July 2013

AbstractThe crystal structures of compounds (III) and (V) are determined by single crystal XRD.
ChemInform Abstract: Ternary Rare‐Earth Ruthenium and Iridium Germanides RE3M2Ge3 (RE: Y, Gd—Tm, Lu; M: Ru, Ir).
Authors: Oliynyk Anton O. , Stoyko Stanislav S. , Mar Arthur 
Published: July 2013

AbstractThe compounds Ln3M2Ge3 (Ln: Y, Gd—Tm, Lu; M: Ru, Ir) are prepared by arc melting of the elements and subsequent annealing at 800 °C for 12 d.
ChemInform Abstract: Direct Catalytic Asymmetric Addition of Allylic Cyanides to Aldehydes for Expeditious Access to Enantioenriched Unsaturated δ‐Valerolactones.
Authors: Otsuka Yasunari , Takada Hisashi , Yasuda Shigeo , Kumagai Naoya , Shibasaki Masakatsu 
Published: July 2013

AbstractThe title reaction, promoted by a soft Lewis acid/hard Broensted base cooperative catalyst, affords homoallylic alcohols with a Z‐configured α,β‐unsaturated nitrile from aromatic aldehydes with electron‐donating substituents, allowing for rapid access to unsaturated γ‐valerolactones like (VIII), which is a key intermediate in the synthesis of fostriecin.
ChemInform Abstract: Nitration of Carbonic, Sulfuric and Oxalic Acid‐Derived Amides in Liquid Carbon Dioxide.
Authors: Kuchurov Ilya V. , Fomenkov Igor V. , Zlotin Sergei G. , Tartakovsky Vladimir A. 
Published: July 2013

AbstractN‐Nitro‐ and N,N‐dinitroamides of carbonic, sulfuric and oxalic acids are prepared by nitration of the corresponding amides with dinitrogen pentoxide in liquid carbon dioxide.
ChemInform Abstract: P4VP‐H2SO4‐Catalyzed Chemoselective Protection of Aldehydes to Acylal Along with Deprotection Reactions.
Authors: Dutta Papia , Sarma Parishmita , Borah Ruli 
Published: July 2013

AbstractPoly(4‐vinylpyridine)‐supported sulfuric acid is an excellent reusable heterogeneous catalyst for the chemoselective protection of a variety of aldehydes as acetals as well as the deprotection of acetals.
ChemInform Abstract: Asymmetric Michael Reaction Catalyzed by Proline Lithium Salt: Efficient Synthesis of L‐Proline and Isoindoloisoquinolinone Derivatives.
Authors: Xu Kun , Zhang Sheng , Hu Yanbin , Zha Zhenggen , Wang Zhiyong 
Published: July 2013

AbstractThe described transformations can be performed with comparable results on a gram scale.
ChemInform Abstract: An Electrophilic Hypervalent Iodine Reagent for Trifluoromethylthiolation.
Authors: Shao Xinxin , Wang Xueqiang , Yang Tao , Lu Long , Shen Qilong 
Published: July 2013

AbstractThe air‐ and moisture‐stable reagent (I) allows the direct transfer of the ‐S‐CF3 group to different classes of substrates such as β‐ketoesters, boronic acids, alkynes, and aldehydes under mild conditions.
ChemInform Abstract: Mild and Rapid Pd‐Catalyzed Cross‐Coupling with Hydrazine in Continuous Flow: Application to the Synthesis of Functionalized Heterocycles.
Authors: DeAngelis Andrew , Wang Dong‐Hui , Buchwald Stephen L. 
Published: July 2013

AbstractContinuous flow or batch reactions of the arylhydrazines, formed in the first step, with β‐diketones, benzaldehyde and ketones allows the synthesis of pyrazoles, hydrazones, and indoles.
ChemInform Abstract: Organocatalytic Asymmetric Cross‐Aldol Reaction of 2‐Chloroethoxy Acetaldehyde: Diversity‐Oriented Synthesis of Chiral Substituted 1,4‐Dioxanes and Morpholines.
Authors: Sawant Rajiv T. , Stevenson Joanne , Odell Luke R. , Arvidsson Per I. 
Published: July 2013

AbstractThe new and facile title reaction affords the novel 1,3‐diols (III) with excellent enantioselectivities and moderate diastereoselectivities.
ChemInform Abstract: DMC‐Mediated One‐Pot Synthesis of Biaryl Ketones from Aryl Carboxylic and Boronic Acids.
Authors: Pathak Arunendra , Rajput Chatrasal S. , Bora Pushkar S. , Sharma Somesh 
Published: July 2013

AbstractCarboxylic acids, activated in situ with DMC, undergo Pd‐catalyzed cross‐coupling reaction with arylboronic acids to produce unsymmetrical aromatic ketones.
ChemInform Abstract: Sulfoximine Directed Intermolecular o‐C—H Amidation of Arenes with Sulfonyl Azides.
Authors: Yadav M. Ramu , Rit Raja K. , Sahoo Akhila K. 
Published: July 2013

AbstractA new Ru(II)‐catalyzed intermolecular ortho‐C—H amidation of various arenes with several sulfonyl azides is reported.
ChemInform Abstract: Chemoselective Synthesis of Aryl Carboxamido Sulfonic Acid Derivatives.
Authors: Lin Po‐Chiao , et al. et al. 
Published: July 2013

AbstractA one‐pot two‐step synthesis of the title compounds, which is more efficient than currently known procedures, is developed and expanded to the synthesis of sulfonic esters, thiosulfonates, and a sulfonyl azide.
ChemInform Abstract: Copper‐Catalyzed Trifluoromethylation of Arylsulfinate Salts Using an Electrophilic Trifluoromethylation Reagent.
Authors: Lin Xiaoxi , Wang Guimei , Li Huaifeng , Huang Yuanyuan , He Weiming , Ye Dandan , Huang Kuo‐Wei , Yuan Yaofeng , Weng Zhiqiang 
Published: July 2013

AbstractThe presented reaction is compatible with a wide range of functional groups in arylsulfinates (I) expanding the scope of Cu‐catalyzed electrophilic triflouromethylation reactions.
ChemInform Abstract: Synthesis of 1‐Arylnaphthalenes by Gold‐Catalyzed One‐Pot Sequential Epoxide to Carbonyl Rearrangement and Cyclization with Arylalkynes.
Authors: Gudla Vanajakshi , Balamurugan Rengarajan 
Published: July 2013

AbstractA one‐pot method for the inter‐ and intramolecular regioselective synthesis of 1‐arylnaphthalenes via a Au‐catalyzed epoxide to carbonyl rearrangement, electrophilic addition to the alkyne, and subsequent benzannulation is presented.
ChemInform Abstract: Organocatalytic 1,4‐Conjugate Addition of Ascorbic Acid to α,β‐Unsaturated Aldehydes: Bio‐Inspired Total Syntheses of Leucodrin, Leudrin and Proposed Structure of Dilaspirolactone.
Authors: Wang Zhaofeng , Zhao Kun , Fu Junkai , Zhang Junlin , Yin Weiyu , Tang Yefeng 
Published: July 2013

AbstractA novel organocatalytic addition of ascorbic acid to α,β‐unsaturated aldehydes via a tandem 1,4‐conjugate addition—hemiacetalization—hemiketalization reaction is developed.
ChemInform Abstract: Pd/C—Cu‐Mediated Direct and One‐Pot Synthesis of γ‐Ylidene Butenolides.
Authors: Rambabu D. , Bhavani S. , Nalivela Kumara Swamy , Mukherjee Soumita , Rao M. V. Basaveswara , Pal Manojit 
Published: July 2013

AbstractIt is found that the catalytic system efficiently promotes the coupling of iodoacrylic acid with terminal alkynes to form the target compounds with high regio‐ and stereoselectivity.
ChemInform Abstract: Synthesis and Structure of Aryl(hetaryl)spiropyrrolidones.
Authors: Berestovitskaya V. M. , Litvinov I. A. , Vasil'eva O. S. , Nikonorov A. A. , Ostroglyadov E. S. , Krivolapov D. B. 
Published: July 2013

AbstractHydrogenation of diastereomerically pure nitroethylpyrrolidinecarboxylates (I) is accompanied by intramolecular acylation of the formed amino group to furnish diastereomerically pure spiropyrrolidines (II).
ChemInform Abstract: Three‐Component Coupling Synthesis of Diversely Substituted N‐Aryl Pyrroles Catalyzed by Iron(III) Chloride.
Authors: Sarkar Soumen , Bera Krishnendu , Maiti Sukhendu , Biswas Srijit , Jana Umasish 
Published: July 2013

AbstractNitroalkenes (I), 1,3‐dicarbonyl compounds, and primary aromatic amines react via a catalytic sequence of Fe(III)‐catalyzed amination/Michael/cycloisomerization reactions to efficiently give the title compounds (IV) (26 examples).
ChemInform Abstract: Synthesis of Highly Functionalized Pyrrolidines as Tunable Templates for the Direct Access to (.+‐.)‐Coerulescine and the Tricyclic Core of Martinellines.
Authors: Le Goff Ronan , Lawson Ata Martin , Daich Adam , Comesse Sebastien 
Published: July 2013

AbstractA series of tetrasubstituted pyrrolidines is synthesized by an aza‐Michael induced ring‐closure tandem reaction of bromide (II) with Michael acceptors (I), (IV), and (VI).
ChemInform Abstract: Domino Synthesis of 3‐Amino‐8‐hydroxy‐1,6‐dioxo‐2,7‐diazaspiro [4.4]non‐3‐ene‐4‐carbonitriles.
Authors: Fedoseev Sergey V. , Ershov Oleg V. , Belikov Mikhail Yu. , Lipin Konstantin V. , Bardasov Ivan N. , Nasakin Oleg E. , Tfeenko Viktor A. 
Published: July 2013

AbstractTreatment of substrates (I) with aqueous NaOH results in cyclization to the spirocyclic title compounds (II) in good yields.
ChemInform Abstract: Fluoride‐Catalyzed Nucleophilic Addition of PhSCF2SiMe3 to Anhydrides: Synthesis of γ‐Difluoromethylated γ‐Lactams.
Authors: Pharikronburee Vannapha , Punirun Teerachai , Soorukram Darunee , Kuhakarn Chutima , Tuchinda Patoomratana , Reutrakul Vichai , Pohmakotr Manat 
Published: July 2013

AbstractThe fluoride‐catalyzed (phenylthio)difluoromethylation of various anhydrides is used as key reaction in the synthesis of difluoromethylated γ‐lactams.
ChemInform Abstract: Ultrasound‐Promoted Synthesis of Novel 2‐Imino‐3‐aryl‐2,3‐dihydrobenzo[d]oxazol‐5‐ol 2‐Iminooxazolidines Derivatives.
Authors: Habibi Davood , Nasrollahzadeh Mahmoud , Sahebekhtiari Hesam , Parish Richard Vernon 
Published: July 2013

AbstractA facile protocol for the synthesis of the title compounds (III) using an ultrasound‐assisted reaction of p‐benzoquinone and arylcyanamides, and their chemoselective tosylation is presented.
ChemInform Abstract: Aza‐Michael Addition Reactions Between Nitroolefins and Benzotriazole Catalyzed by MCM‐41 Immobilized Heteropoly Acids in Water.
Authors: Xie Shao‐Lei , Hui Yong‐Hai , Long Xiang‐Ju , Wang Chang‐Chun , Xie Zheng‐Feng 
Published: July 2013

AbstractThe reusable catalyst is applied to the preparation of functionalized nitroalkanes bearing a heterocyclic skeleton as products of interest in natural compound synthesis and drug discovery.
ChemInform Abstract: Efficient Transformation of Inactive Nitriles into 5‐Substituted 1H‐Tetrazoles Using Microwave Irradiation and Their Applications.
Authors: Yoneyama Hiroki , Usami Yoshihide , Komeda Seiji , Harusawa Shinya 
Published: July 2013

AbstractThe practical method allows the preparation of various types of tetrazole compounds.
ChemInform Abstract: One‐Step Synthesis of 5,6‐Diaryl Pyridine‐2(1H)‐thiones from Isoflavones.
Authors: Wang Juanjuan , Zhang Zunting , Wang Wenli , Liu Fangfang 
Published: July 2013

AbstractThe title process involves a base‐mediated isoflavone ring opening followed by Knoevenagel condensation between the resulting 1,3‐dicarbonyl intermediate and cyanothioacetamide.
ChemInform Abstract: A Novel Three‐Component [5 + 1] Heterocyclization Leading to 2‐Azafluorenone Synthesis and Its Polyfunctionalizations.
Authors: Li Ying , Fan Wei , Xu Hai‐Wei , Jiang Bo , Wang Shu‐Liang , Tu Shu‐Jiang 
Published: July 2013

AbstractHighly functionalized 2‐azafluorenones are synthesized by domino reactions involving C1‐aryl acylation, C3‐thiolation, and C4‐cyanation under mild conditions in short reaction times (15‐30 min).
ChemInform Abstract: A Novel Convenient Approach Towards Pyrrolo[1,2‐b]pyridazines Through a Domino Coupling—Isomerization—Condensation Reaction.
Authors: Wang Meng , Tan Cun , He Qian , Xie Yuyuan , Yang Chunhao 
Published: July 2013

AbstractA novel Pd/Cu catalyzed synthesis of pyrrolopyridazines under mild conditions is developed.
ChemInform Abstract: Trifluoroethanol Solvent Facilitates Selective N‐7 Methylation of Purines.
Authors: Lebraud Honorine , Cano Celine , Carbain Benoit , Hardcastle Ian R. , Harrington Ross W. , Griffin Roger J. , Golding Bernard T. 
Published: July 2013

AbstractAn one‐pot process is elaborated for the preparation of 7‐alkylpurines in trifluoroethanol by a N‐7 alkylation of purines (I) bearing Pmb‐protecting group at N‐9 followed by a microwave‐induced deprotection.
ChemInform Abstract: Synthesis of Linear and Cyclic Compounds Containing the 3,4‐Bis(Furazan‐3‐yl)furoxan Fragment.
Authors: Stepanov A. I. , Astrat'ev A. A. , Dashko D. V. , Spiridonova N. P. , Mel'nikova S. F. , Tselinskii I. V. 
Published: July 2013

AbstractReactions of furoxan (I) with a series of N‐ and O‐nucleophiles provides access to novel heterocyclic systems.
ChemInform Abstract: The Staudinger Reaction with 2‐Imino‐1,3‐thiaselenanes Toward the Synthesis of C4 Spiro‐β‐lactams.
Authors: Toyoda Yosuke , Ninomiya Masayuki , Ebihara Masahiro , Koketsu Mamoru 
Published: July 2013

AbstractA variety of C4 spiro‐β‐lactams are synthesized via the Staudinger reaction of readily available 2‐imino‐1,3‐thiaselenanes (III) with methoxyketene.
ChemInform Abstract: Quinic Acid Derivatives from Pimpinella brachycarpa Exert Antineuroinflammatory Activity in Lipopolysaccharide‐Induced Microglia
Authors: Lee Seung Young , Moon Eunjung , Kim Sun Yeou , Lee Kang Ro 
Published: July 2013

Abstractisolation, structure and antineuroinflammatory activity of five new quinic acid derivatives (I) together with ten known quinic acids
ChemInform Abstract: Aculeatusquinones A—D, Novel Metabolites from the Marine‐Derived Fungus Aspergillus aculeatus.
Authors: Chen Li , Zhang Wei‐Wei , Zheng Qiu‐Hong , Liu Qing‐Ying , Zhong Ping , Hu Xiao , Fang Zhe‐Xiang , Zhang Qi‐Qing 
Published: July 2013

AbstractAculeatusquinones B (II) and D (IV) demonstrate weak to moderate cytotoxicity against HL‐60, K562, and A‐549 cell lines.