bluuebunny/crossref_metadata_2025_split huggingface dataset:
Enhanced recovery after surgery-based nursing in older patients with postoperative intestinal obstruction after gastric cancer surgery: A retrospective study
Authors: Li Yu-Qin , Liu Ying , Peng Zhu-Qing , Fang Rong , Xu Hai-Yan 
Published: June 2024

BACKGROUND
Gastric cancer-related morbidity and mortality rates are high in China. Patients who have undergone gastric cancer surgery should receive six cycles of chemotherapy according to their condition. During this period, intestinal obstruction is likely to occur. Electrolyte balance disorders, peritonitis, intestinal necrosis, and even hypovolemic shock and septic shock can seriously affect the physical and mental recovery of patients and threaten their health and quality of life (QoL).
AIM
To quantitatively explore the effects of enhanced recovery after surgery (ERAS)–based nursing on anxiety, depression, and QoL of elderly patients with postoperative intestinal obstruction after gastric cancer.
METHODS
The clinical data of 129 older patients with intestinal obstruction after gastric cancer surgery who were treated and cared for in our hospital between January 2019 and December 2021 were examined retrospectively. Nine patients dropped out because of transfer, relocation, or death. According to the order of admissions, the patients were categorized into either a comparison group or an observation group according to the random number table, with 60 cases in each group.
RESULTS
After nursing care, the observation group required significantly less time to eat for the first time, recover bowel sounds, pass gas, and defecate than the comparison group (P < 0.05). No significant difference was noted in nutrition-related indicators between the two groups before care. Before care, the Symptom Check List-90 scores between the two groups were comparable, whereas anxiety, depression, paranoia, fear, hostility, obsession, somatization, interpersonal sensitivity, and psychotic scores were significantly lower in the observation group after care (P < 0.05). The QoL scores between the two groups before care did not differ significantly. After care, the physical, social, physiological, and emotional function scores; mental health score; vitality score; and general health score were significantly higher in the observation group, whereas the somatic pain score was significantly lower in the observation group (P < 0.05).
CONCLUSION
ERAS-based nursing combined with conventional nursing interventions can effectively improve patient’s QoL, negative emotions, and nutritional status; accelerate the time to first ventilation; and promote intestinal function recovery in elderly patients with postoperative intestinal obstruction after gastric cancer surgery.
Clinical efficacy of gamma-oryzanol combined with Femoston for perimenopausal syndrome
Authors: Kuang Yang-Yang , Xiong Min-Qi , Cai Jin-Xia 
Published: June 2024

BACKGROUND
Perimenopausal syndrome (PMS) is a chronic disease associated with estrogen deficiency. Because of the unsatisfactory outcomes of current conventional treatments for this condition, its treatment must be continuously explored and optimized.
AIM
To assess the clinical effectiveness of γ-oryzanol in combination with Femoston for PMS.
METHODS
A total of 119 patients with PMS were selected from June 2023 to December 2023, which included 59 and 60 patients in the control and observation group, respectively. The control and observation groups were treated with Femoston and γ-oryzanol + Femoston, respectively. Comparative analyses were performed in terms of clinical effectiveness, safety (dizziness and headache, nausea and vomiting, and breast tenderness), sex hormones [estradiol (E2), luteinizing hormone (LH), and follicle-stimulating hormone (FSH)], lumbar spine (L1–4) and bilateral femoral bone mineral density (BMD), and sleep quality (sleeping time and frequency of awakenings from sleep).
RESULTS
Compared with the control group, the observation group had statistically higher total effective rates of treatment; lower overall incidence of adverse events; higher post-treatment E2 levels and L1–4 and bilateral femoral BMD; and lower LH and FSH levels, sleeping time, and frequency of awakenings from sleep after treatment.
CONCLUSION
Therefore, for the treatment of PMS, γ-oryzanol combined with Femoston is significantly better than Femoston alone in terms of clinical effectiveness, exhibiting more pronounced clinical advantages in improving safety, sex hormone levels, BMD, and sleep quality.
Mimicking aneurysm in a patient with chronic occlusion of the left middle cerebral artery: A case report
Authors: Yang Sen , Mai Rong-Kang 
Published: June 2024

BACKGROUND
With the popularization of various cerebrovascular imaging methods and increased attention to the field, more cerebrovascular diseases are being detected in asymptomatic patients. Different cerebrovascular diseases are typically isolated but occasionally occur simultaneously, causing difficulties in diagnosis and treatment. Morphological changes in the collateral circulation of blood vessels in chronic cerebral artery occlusion patients are slow and dynamic, intercepting morphological development at a specific moment. Excessive reliance on single imaging tests such as digital subtraction cerebral angiography (DSA) can lead to misdiagnosis.
CASE SUMMARY
We report a 52-year-old male who was admitted to our department for treatment of an unruptured aneurysm during a follow-up examination for brain trauma after 1 mo. Computed tomography (CT) scan was negative, but CT angiography (CTA) revealed a sac-like bulge at the bifurcation of the left middle cerebral artery. DSA revealed an unruptured aneurysm with unique scapular morphology. The stump of a middle cerebral artery occlusion was observed during exposure during aneurysm clipping surgery, and the diagnosis of chronic cerebral artery occlusion was confirmed intraoperatively. This case was confusing because of the peculiar morphology of the arterial stump and compensatory angiogenesis due to multiple cerebral artery stenoses observed on preoperative CTA and DSA. The surgery did not cause secondary damage to the patient, and medical treatment for risk factors was continued postoperatively.
CONCLUSION
Multiple cerebral arterial stenoses can occur in conjunction with aneurysms or arteriovenous malformations, and their unique morphology can lead to misdiagnosis.
Lymphovenous anastomosis and complex decongestive therapy for severe deformed lymphedema with recurrent infection: A case report
Authors: Wang He-Jun , He Qing-Qing , Liu Chang-Rui , Wang Ying-Ying , Liu Xun-Wei 
Published: June 2024

BACKGROUND
Lower extremity lymphedema is a common complication following treatment for gynecological malignancies. Its incidence rate can reach up to 70%, affecting ~20 million people worldwide. However, specialized treatment centers are scarce, and there is a lack of consensus on treatment approaches. Furthermore, there are even fewer reports on the systematic and effective treatment of severe lymphedema with malformations. Effective management of this condition remains a significant challenge for clinicians.
CASE SUMMARY
A 40-year-old woman developed bilateral leg swelling 6 years after receiving treatment for endometrial cancer. Since August 2018, she experienced > 30 episodes of lymphangitis. Upon presentation, she exhibited bilateral leg swelling and deformation, with four large swellings in the posterior thigh that impeded movement, and pain in the limbs. Skin manifestations included lichenoid lesions and features of deep sclerosis. Radionuclide lymphoscintigraphy confirmed the diagnosis of lower limb lymphedema. After 6 mo of complex decongestive therapy (CDT) and three lymphaticovenous anastomosis (LVA) treatments, the patient lost 49 kg in weight. She also experienced a maximum circumference reduction of 35.2 cm in the left lower limb and 37.5 cm in the right lower limb. The leg pain disappeared, her swelling significantly decreased, and she regained the ability to walk, cycle, and run normally.
CONCLUSION
The combined application of CDT and LVA therapy demonstrates significant positive effects in the treatment of severe, deformed stage III lymphedema.
Glucocorticoid therapy in pancreatic portal hypertension associated with autoimmune pancreatitis: A case report
Authors: Zhang Yi , Li Zhao-Dong , He Yuan-Jing , Peng Wei , Luo Yu-Jun , Li Xiao-An 
Published: June 2024

BACKGROUND
Autoimmune pancreatitis (AIP) is a chronic form of pancreatitis characterized by diffused enlargement of the pancreas and irregular stenosis of the main pancreatic duct. Some studies have reported that AIP can cause hemorrhage of gastric varices (GV) related to portal hypertension (PH). However, such cases are rare. In addition, the association of PH with AIP is unclear. At the same time, the efficacy and duration of glucocorticoid therapy is also controversial.
CASE SUMMARY
In this case, we reported a case of GV in pancreatic PH associated with AIP. Enhanced abdominal computed tomography (CT) suggested splenic vein (SV) and superior mesenteric vein (SMV) thromboses. The patient received a long-term glucocorticoid therapy, that the initial dose of 40 mg is reduced weekly by 5 mg, and then reduced to 5 mg for long-term maintenance. CT and gastroscopic examination after 8 mo of treatment indicated that SV and SMV were recanalized, pancreatic stiffness and swelling were ameliorated, and the GV almost completely disappeared.
CONCLUSION
Long-term glucocorticoid therapy can alleviate the development of GV in patients with AIP and has potential reversibility.
Giant retroperitoneal hemolymphangioma: A case report and review of literature
Authors: Wang Yi-Kai , Liu Ying-Hao , Shuang Wei-Bing 
Published: June 2024

BACKGROUND
Hemolymphangioma is a very rare benign tumor in clinical practice caused by abnormalities of the vasculature. Its clinical features are often atypical, and it is easy to miss and misdiagnose. When the time of nuclear magnetic T1 is significantly reduced, the diagnosis of hemangioma should be considered. Therefore, we report this case in the hope of raising clinicians' awareness of the disease.
CASE SUMMARY
A 37-year-old man presented with a giant retroperitoneal hemolymphangioma. Computed tomography and magnetic resonance imaging indicated the possibility of a large perirenal lymphatic cyst. The postoperative pathological diagnosis is retroperitoneal hemolymphangioma. The patient underwent surgical excision after adequate drainage. The postoperative recovery was smooth and there were no complications. There was no recurrence during half a year of follow-up.
CONCLUSION
This case reiterates that large retroperitoneal cystic masses with significantly shortened nuclear T1 time should be considered hemolymphangioma. Specific clinical basis and experience for the diagnosis and treatment of these diseases is necessary.
Selective his bundle pacing eliminates crochetage sign: A case report
Authors: Mu Yan-Guang , Liu Ke-Sen 
Published: June 2024

BACKGROUND
Crochetage sign is a specific electrocardiographic manifestation of ostium secundum atrial septal defects (ASDs), which is associated with the severity of the left-to-right shunt. Herein, we reported a case of selective his bundle pacing (S-HBP) that eliminated crochetage sign in a patient with ostium secundum ASD.
CASE SUMMARY
A 77-year-old man was admitted with a 2-year history of chest tightness and shortness of breath. Transthoracic echocardiography revealed an ostium secundum ASD. Twelve-lead electrocardiogram revealed atrial fibrillation with a prolonged relative risk interval, incomplete right bundle branch block, and crochetage sign. The patient was diagnosed with an ostium secundum ASD, atrial fibrillation with a second-degree atrioventricular block, and heart failure. The patient was treated with selective his bundle pacemaker implantation. After the procedure, crochetage sign disappeared during his bundle pacing on the electrocardiogram.
CONCLUSION
S-HBP eliminated crochetage sign on electrocardiogram. Crochetage sign may be a manifestation of a conduction system disorder.
Short Communication: Investigation of mecA-positive and Methicillin-Resistant Staphylococcus aureus (MRSA) in dairy goat with subclinical mastitis from traditional farms in Banyuwangi, Indonesia
Authors: PRAJA RATIH NOVITA , EDILA RYANKA , YUDHANA ADITYA , SAPUTRO AMUNG LOGAM , HAMONANGAN JONATHAN MARK , PRAJA SHIFA SALSABILLA 
Published: June 2024

Abstract. Praja RN, Edila R, Yudhana A, Saputro AL, Hamonangan JM, Praja SS. 2024. Short Communication: Investigation of mecA-positive and Methicillin-Resistant Staphylococcus aureus (MRSA) in dairy goat with subclinical mastitis from traditional farms in Banyuwangi, Indonesia. Biodiversitas 25: 1638-1643. Raw milk has the potential to transmit bacteria resistant to antibiotics and serve as a medium for the development of food-borne illnesses. Staphylococcus aureus is a harmful bacterium that can infect host cells and carry antibiotic-resistant genes. This study aims to investigate the occurrence of Methicillin-Resistant Staphylococcus aureus (MRSA) which contains mecA coding gene from raw goat milk in Banyuwangi, East Java, Indonesia. 150 raw milk samples were collected from five goat farms in Banyuwangi, East Java, Indonesia. S. aureus was isolated using selective media, and antibiotic susceptibility testing was conducted using the Mueller-Hinton agar diffusion method. MRSA was confirmed using the oxacillin and cefotaxime resistance screen agar test, with the presence of mecA genes identified through polymerase chain reaction. The results show that the prevalence of S. aureus was 30.6%. Of the 46 S. aureus isolates, 28 (60.87%) were categorized as MRSA. The mecA gene was observed in 9 (32.14%) MRSA isolates. The presence of MRSA in raw goat milk poses a significant public health threat, as bacteria carrying the mecA gene for antimicrobial resistance can spread through animal products like raw milk. Enhanced hygiene and sanitation protocols in dairy goat farms are essential prevention measures that must be strictly implemented.
Gastroschisis survival improvement and early intervention: experience in a developing country
Authors: Rahayatri Tri Hening , Gunardi Harsya Dwindaru , Amin Rusdah Binti Muhammad , Tamba Riana Pauline 
Published: July 2024

Background Gastroschisis is the most common abdominal congenital defect worldwide. While the mortality rate is 5–10% in developed countries, the rate escalates in developing countries due to less access to surgical care, and studies on the condition are scarce. Gastroschisis mortality and morbidity rates in Indonesia are unknown or unclear; little is also known about influencing factors that reveal epidemiological characteristics.
Objective To identify the rate and factors associated with gastroschisis mortality in Indonesia.
Methods A retrospective cohort study was conducted at Dr. Cipto Mangunkusumo Hospital, which included neonates with gastroschisis who underwent defect closure surgery from January 2015 to September 2020. We explored possible influencing risk factors, including gestational age, birth weight, number of surgeries, age at closure, and presence of gastroschisis complications. Bivariate analysis was done using Chi-square or Fisher’s test.
Results Of 49 neonates with gastroschisis, 42 were included in the study. Seven neonates were excluded due to incomplete medical records. The mortality rate of gastroschisis based on our data was 69%. The age at closure (<1 day) was significantly associated with lower mortality rate (P=0.005). In contrast, other factors, including gestational age, birth weight, number of surgeries, and the presence of complicated gastroschisis were not the risk factors of gastroschisis mortality.
Conclusion The mortality rate of gastroschisis is high in Indonesia, specifically at Dr. Cipto Mangunkusumo Hospital. Immediate closure is significantly associated with a decreased likelihood of death. Awareness, diagnosis, and efficient referral of gastroschisis from remote areas to a tertiary facility must be encouraged to reduce the high mortality rate.
SMART LOCK DOOR BERBASIS DIGITAL MENGGUNAKAN RFID RC522 DAN MICROCONTROLLER ARDUINO NANO
Authors: Muzaki Imam , Amal Mochamad Ikhlasul , AlFarisi Masdi 
Published: June 2024

Sistem keamanan yang semakin maju, pengamanan pintu rumah menjadi hal yang sangat penting. Setiap rumah pasti memiliki pintu. Di era sekarang ini kunci konvensional sangat mudah dibuka oleh pencuri, sehingga diperlukannya kunci yang lebih praktis dan tingkat pengamanan yang tinggi. Solusi inovatif yang memanfaatkan sistem digital dan teknologi RFID dengan memanfaatkan E-KTP untuk memberikan keamanan tambahan dan kemudahan akses bagi pengguna. Dalam penelitian ini kami menggunakan komponen utama, yaitu RFID RC55 sebagai metode identifikasi pengguna, mikrokontroler Arduino Nano sebagai otak dari sistem, dan beberapa sensor pendukung lainnya. Sistem ini dirancang untuk menggantikan kunci konvensional dan memberikan kemampuan untuk membuka dan mengunci pintu secara otomatis melalui identifikasi RFID. Penelitian ini melibatkan tahap perancangan, dan pemrograman perangkat lunak. Metode pengujian dan evaluasi dilakukan untuk memastikan kehandalan dan keamanan sistem smartlock door ini. Hasil penelitian ini berupa kode akses yaitu “73 f0 2a 96” dari RFID card 1, “04 3a 91 a2 11 5e 80” dari KTP 1, “04 80 61 9a 10 2a 80” dari KTP 2, dan “02 05 86 90 04 40 00” dari SIM.
Physiological network approach to prognosis in cirrhosis: A shifting paradigm
Authors: Oyelade Tope , Moore Kevin P. , Mani Ali R. 
Published: July 2024

AbstractDecompensated liver disease is complicated by multi‐organ failure and poor prognosis. The prognosis of patients with liver failure often dictates clinical management. Current prognostic models have focused on biomarkers considered as individual isolated units. Network physiology assesses the interactions among multiple physiological systems in health and disease irrespective of anatomical connectivity and defines the influence or dependence of one organ system on another. Indeed, recent applications of network mapping methods to patient data have shown improved prediction of response to therapy or prognosis in cirrhosis. Initially, different physical markers have been used to assess physiological coupling in cirrhosis including heart rate variability, heart rate turbulence, and skin temperature variability measures. Further, the parenclitic network analysis was recently applied showing that organ systems connectivity is impaired in patients with decompensated cirrhosis and can predict mortality in cirrhosis independent of current prognostic models while also providing valuable insights into the associated pathological pathways. Moreover, network mapping also predicts response to intravenous albumin in patients hospitalized with decompensated cirrhosis. Thus, this review highlights the importance of evaluating decompensated cirrhosis through the network physiologic prism. It emphasizes the limitations of current prognostic models and the values of network physiologic techniques in cirrhosis.
Temperature optimization model to inhibit zero-order kinetic reactions
Authors: Januardi Januardi , Nugraha Aditya Sukma 
Published: July 2024

Abstract
Originally, the Arrhenius parameters were used to estimate the rate of chemical reactions. This article aims to develop the optimal temperature to inhibit specific zero-order kinetic reactions. The model extends the use of the Arrhenius equation and heat capacity modeling to derive the optimal temperature solution. Specifically, the Arrhenius equation, which connects temperature to reaction rates, and the heat equation are formulated to create a comprehensive heat accumulation model. Analytical modeling is utilized through a derivative process to provide optimization. According to a case study of carotene oxidation, the derivative solution proposes −1.73 °C and can extend the reaction time by 206,160.29 days compared to a solution with no temperature change. The derivative solution also offers higher advantages in practical application than setting the lowest temperature limit due to the high initial energy requirement. The temperature derivative solution exhibits a global optimum property because of its high heat accumulation and slower kinetic reactions. These slower kinetic reactions can prevent reactant substances from deteriorating, making them valuable for maintaining a chemical’s shelf life. The temperature solutions offer valuable insights for devising an effective temperature strategy to inhibit specific chemical processes and verifying the relationship between temperature and heat accumulation with curvature.
Kraft pulping of model wood chips: local impact of process conditions on hardwood delignification and xylan retention
Authors: Marion de Godoy Carolina , Hasani Merima , Theliander Hans 
Published: July 2024

Abstract
Local evolution of delignification and xylan removal inside wood chips was investigated throughout the initial stages of kraft cooking. Model chips of birch sapwood were pulped at 145, 155 and 165 °C, utilizing white liquors with hydroxide content ranging from 0.25 to 0.55 mol/kg. The composition of different sections in each cooked sample was then determined. Xylan was isolated from selected samples and analyzed using size exclusion chromatography and HSQC NMR. Most changes in concentration and structure of residual xylan occurred early in the process (<45 min). Furthermore, xylan samples isolated from the tissue of different cooked chips had similar average molecular weights, indicating that temperature and alkali content had little impact over the extent of reactions affecting residual xylan. In contrast, xylan dissolution was significantly dependent on pulping conditions, increasing with hydroxide concentration. The lignin profile inside the cooked chips also varied with alkali content and temperature, and it was shown to be more uniform when applying low cooking temperatures (145 °C). Finally, increased delignification and xylan removal were detected close to the transverse surfaces of chips (likely due to the fast mass transport in vessels/lumen), implying that anatomical features of wood can have a significant impact on pulping.
Novel homozygous mutation in SCNN1A gene in an Iranian boy with PHA1B
Authors: Saffari Fatemeh , Bahadoran Ensiyeh , Homaei Ali , Moghbelinejad Sahar 
Published: July 2024

Abstract

Objectives
Pseudohypoaldosteronism type 1 (PHA1) has two genetically distinct variants, including renal and systemic forms. Systemic PHA type I (PHA1B) has varying degrees of clinical presentation and results from mutations in genes encoding subunits of the epithelial sodium channel (ENaC) including the alpha, beta, and gamma subunits. To date, about 45 variants of PHA1B have been identified.

Case presentation
We report a boy with PHA1B, who presented with vomiting, lethargy, and poor feeding due to salt wasting six days after birth. The patient had electrolyte imbalances. A novel SCNN1A (sodium channel epithelial subunit alpha) gene mutation, NM_001038.6:c.1497G>C, with an autosomal recessive pattern, was identified by whole exosome sequencing. This variant was inherited as a homozygote from both heterozygous parents.

Conclusions
PHA should be considered in neonates with hyponatremia and hyperkalemia. This case report presents a patient with a novel mutation in SCNN1A that has not been previously reported. Long-term follow-up of identified patients to understand the underlying phenotype-–genotype link is necessary.