bluuebunny/crossref_metadata_2025_split huggingface dataset:
Family Presence in the Adult Burn Intensive Care Unit During Dressing Changes
Authors: Bishop Sarah M. , Walker Mandi D. , Spivak I. Mark 
Published: February 2013

ObjectivesTo improve communication, discharge readiness, and satisfaction of burn patients and their families.MethodsIn March 2009, the burn intensive care unit at University of Louisville Hospital, Louisville, Kentucky, incorporated family presence during dressing changes. Adverse family events during observation, measures of patient- and family-centered care according to a standardized patient satisfaction survey, infection rates, and staff members’ response to the intervention were tracked.ResultsThrough December 2011, no adverse family events occurred, patients’ satisfaction scores increased, and infection rates did not increase. Staff members responded positively to the project.ConclusionsAllowing family presence during dressing changes provides an opportunity to educate and include patients’ family members in care delivery.
The terrestrial invertebrate fauna of the Svalbard archipelago in a changing world: history of research and challenges
Authors: Coulson Stephen James 
Published: February 2013

AbstractThe High Arctic represents a unique environment, an environment from where knowledge is limited and which is currently experiencing rapid change. The archipelago of Svalbard in the European High Arctic possesses a terrestrial and freshwater invertebrate fauna that is distinctive and diverse. However, the majority of studies concentrate on the fauna of the comparatively mild west coast. Very few investigations of the colder east coast exist. Furthermore, scientific investigations are relatively recent. Scientific records of the terrestrial invertebrate fauna begin in the mid-19th century with species inventories and community descriptions but experimental field-based studies and physiological investigations did not commence until the 1980s. Some 570 articles consider this fauna, 54% of which have appeared since 1990. There is hence a dramatic and rapid increase in our understanding, which is not only improving our comprehension of Arctic ecosystem functioning but also providing a baseline for environmental change studies. Due to a largely pristine environment, a political focus and relative ease of logistics, Svalbard is set to become a focus of such studies. This article considers the state of knowledge of the terrestrial and freshwater invertebrate fauna of Svalbard, current research, and discusses the threats to the distinctive communities.
El futuro de la TV europea es híbrido, convergente y cada vez menos público
Authors: Campos Freire Francisco 
Published: February 2013

La televisión pública en Europa pierde peso e influencia en las políticas de comunicación de esta segunda década del siglo XXI, en sus propios medios de financiación, en la lucha por las audiencias y en los sistemas tecnológicos de difusión frente a los nuevos modelos híbridos y convergentes abanderados por los operadores de cable, de satélite y de la distribución por Internet (IPTV). Frente a la fragmentación de audiencias y al debilitamiento de los modelos de financiación tradicionales (publicidad, canon, subvención), las televisiones concentran sus estrategias de difusión en las economías de escala y de club a través de duopolios o plataformas integradas de mercado.
The Consequences of Social Processes: Aggregate Populations, Projectile Point Accumulation, and Subsistence Patterns in the American Southwest
Authors: Arakawa Fumiyasu , Nicholson Christopher , Rasic Jeff 
Published: February 2013

AbstractTracking broad-scale behavioral patterns using both lithics and faunal remains offers one line of evidence for investigating both prehistoric subsistence activities and the consequences of aggregation and increases in population size. Accumulation research, which examines the ratio of projectile points to cooking pottery sherds from the same context, shows a higher ratio of projectile points in areas with lower population densities. This pattern holds true when examining faunal assemblages and large-game procurement practices from A.D. 900 to 1300 in southwestern Colorado and southeastern Utah. This research demonstrates that social processes such as aggregation and increases in population density influence human hunting strategies as much as changes in natural environment, which lead to changes in a group’s dietary regime.
The Allure of the Exotic: Reexamining the Use of Local and Distant Pipestone Quarries in Ohio Hopewell Pipe Caches
Authors: Emerson Thomas E. , Farnsworth Kenneth B. , Wisseman Sarah U. , Hughes Randall E. 
Published: February 2013

AbstractMary W. Helms’s observation that spatial distance often correlates with spiritual power has become an axiom in interpreting the role of exotic materials in societies. This is especially evident in explanations of the North American Hopewell Interaction Sphere. The circulation and accumulation of exotic materials in massive mortuary caches peaked during the Hopewell era (100 B.C. to A.D. 300). The premise that Hopewell smoking pipes were made in Ohio, primarily of local raw material, and circulated to foreign locations was an integral part of this interaction model. In this study we demonstrate, primarily using reflectance near-infrared spectroscopy (NIS), that early Hopewell Tremper Mound pipe raw-material acquisition focused on exotic pipestones from Illinois and Minnesota. By contrast, later Mound City cache pipes were almost exclusively made from local limestone and pipestone. The discovery of this shift in preference for and/or access to different quarry sources by Ohio Hopewell societies provides new perspectives on early Hopewell development and long-distance interaction.
Farming and Foraging at the Crossroads: The Consequences of Cherokee and European Interaction Through the Late Eighteenth Century
Authors: VanDerwarker Amber M. , Marcoux Jon B. , Hollenbach Kandace D. 
Published: February 2013

AbstractThe material remains of daily subsistence within Cherokee communities reflect strategies that households enacted while adapting to disruptions associated with European colonialism. Plant subsistence remains dating from the late Pre-Contact period through the end of the Revolutionary War (A.D. 1300–1783) reveal how Cherokee food producers! collectors fed their families as they navigated an increasingly uncertain landscape. Framing our analysis in terms of risk mitigation and future-discounting concepts from human behavioral ecology, we argue that Cherokee households responded to increasing risk and uncertainty by shifting towards subsistence strategies that had more immediate rewards. Although Cherokee plant subsistence remains exhibit continuity in how people farmed and foraged, our study shows that households made strategic decisions to alter their food production and collection with respect to looming uncertainty. Archaeobotanical analysis from multiple sites spanning the Colonial period (ca. A.D. 1670–1783) reveal a stepwise process of declining maize production, increased foraging, and overall diversification of the plant diet. This case underscores the relevance of concepts from human behavioral ecology to complex colonial situations by demonstrating that strategies of risk prevention and mitigation have applicability beyond ecological factors.
The Study of Indigenous Political Economies and Colonialism in Native California: Implications for Contemporary Tribal Groups and Federal Recognition
Authors: Lightfoot Kent G. , Panich Lee M. , Schneider Tsim D. , Gonzalez Sara L. , Russell Matthew A. , Modzelewski Darren , Molino Theresa , Blair Elliot H. 
Published: February 2013

AbstractThis article advocates for a comparative approach to archaeological studies of colonialism that considers how Native American societies with divergent political economies may have influenced various kinds of processes and outcomes in their encounters with European colonists. Three dimensions of indigenous political economies (polity size, polity structure, and landscape management practices) are identified as critical variables in colonial research. The importance of considering these dimensions is exemplified in a case study from California, which shows how small-sized polities, weak to moderate political hierarchies, and regionally oriented pyrodiversity economies played significant roles in the kinds of colonial relationships that unfolded. The case study illustrates how the colonial experiences of Native Californians differed from those of other tribal groups that confronted similar kinds of colonial programs involving Franciscan missionaries elsewhere in North America. The article stresses that the archaeology of colonialism is not simply an arcane academic exercise but, rather, has real-life relevancy for people who remain haunted by the legacies of colonialism, such as those petitioning for federal recognition in California.
De nouvelles perspectives pour la recherche en management international
Authors: Lemaire Jean-Paul , Mayrhofer Ulrike , Milliot Eric 
Published: February 2013

Cet article porte sur les effets de l’accélération de l’intégration mondiale d’espaces économiques, multiples et enchevêtrés, dans le but de permettre aux différents acteurs impliqués d’en cerner les enjeux. Les auteurs identifient quatre axes de recherche, bien souvent interconnectés, dans le champ du Management et du Développement International des organisations : l’intégration de nouvelles logiques de diagnostic et de prise de décision, la prise en compte de nouveaux profils de parties prenantes, la montée en puissance de nouveaux rapports de force entre espaces et acteurs économiques, et les relations entre schémas organisationnels et évolutions interculturelles au sein des organisations.
Les effets de la notation financière sur les stratégies d’internationalisation des firmes multinationales européennes
Authors: Lantin François 
Published: February 2013

Les sociétés sont contraintes dans leur stratégie d’internationalisation par leur niveau d’endettement révélé par leur notation financière. En s’appuyant sur 402 changements de note de 182 firmes multinationales européennes annoncés par Standard and Poor’s, les résultats valident l’asymétrie moyenne de réaction des marchés d’actions : diminution du cours boursier suite aux dégradations de note mais absence de réaction consécutive aux relèvements. Cependant, les variations individuelles des prix des actions ne seraient fortement négatives que dans la moitié des cas pour les baisses de note et nulles voire positives dans l’autre moitié. Des résultats symétriques sont obtenus pour les hausses de note.
Large-Scale Proteomics in Early Pregnancy and Hypertensive Disorders of Pregnancy
Authors: Greenland Philip , Segal Mark R. , McNeil Rebecca B. , Parker Corette B. , Pemberton Victoria L. , Grobman William A. , Silver Robert M. , Simhan Hyagriv N. , Saade George R. , Ganz Peter , Mehta Priya , Catov Janet M. , Bairey Merz C. Noel , Varagic Jasmina , Khan Sadiya S. , Parry Samuel , Reddy Uma M. , Mercer Brian M. , Wapner Ronald J. , Haas David M. 
Published: July 2024

ImportanceThere is no consensus regarding the best method for prediction of hypertensive disorders of pregnancy (HDP), including gestational hypertension and preeclampsia.ObjectiveTo determine predictive ability in early pregnancy of large-scale proteomics for prediction of HDP.Design, Setting, and ParticipantsThis was a nested case-control study, conducted in 2022 to 2023, using clinical data and plasma samples collected between 2010 and 2013 during the first trimester, with follow-up until pregnancy outcome. This multicenter observational study took place at 8 academic medical centers in the US. Nulliparous individuals during first-trimester clinical visits were included. Participants with HDP were selected as cases; controls were selected from those who delivered at or after 37 weeks without any HDP, preterm birth, or small-for-gestational-age infant. Age, self-reported race and ethnicity, body mass index, diabetes, health insurance, and fetal sex were available covariates.ExposuresProteomics using an aptamer-based assay that included 6481 unique human proteins was performed on stored plasma. Covariates were used in predictive models.Main Outcomes and MeasuresPrediction models were developed using the elastic net, and analyses were performed on a randomly partitioned training dataset comprising 80% of study participants, with the remaining 20% used as an independent testing dataset. Primary measure of predictive performance was area under the receiver operating characteristic curve (AUC).ResultsThis study included 753 HDP cases and 1097 controls with a mean (SD) age of 26.9 (5.5) years. Maternal race and ethnicity were 51 Asian (2.8%), 275 non-Hispanic Black (14.9%), 275 Hispanic (14.9%), 1161 non-Hispanic White (62.8% ), and 88 recorded as other (4.8%), which included those who did not identify according to these designations. The elastic net model, allowing for forced inclusion of prespecified covariates, was used to adjust protein-based models for clinical and demographic variables. Under this approach, no proteins were selected to augment the clinical and demographic covariates. The predictive performance of the resulting model was modest, with a training set AUC of 0.64 (95% CI, 0.61-0.67) and a test set AUC of 0.62 (95% CI, 0.56-0.68). Further adjustment for study site yielded only minimal changes in AUCs.Conclusions and RelevanceIn this case-control study with detailed clinical data and stored plasma samples available in the first trimester, an aptamer-based proteomics panel did not meaningfully add to predictive utility over and above clinical and demographic factors that are routinely available.
Early Prostate Cancer Deaths Among Men With Higher vs Lower Genetic Risk
Authors: Plym Anna , Zhang Yiwen , Stopsack Konrad H. , Ugalde-Morales Emilio , Seibert Tyler M. , Conti David V. , Haiman Christopher A. , Baras Aris , Stocks Tanja , Drake Isabel , Penney Kathryn L. , Giovannucci Edward , Kibel Adam S. , Wiklund Fredrik , Mucci Lorelei A. ,   Regeneron Genetics Center
Published: July 2024

ImportanceProstate cancer, a leading cause of cancer death among men, urgently requires new prevention strategies, which may involve targeting men with an underlying genetic susceptibility.ObjectiveTo explore differences in risk of early prostate cancer death among men with higher vs lower genetic risk to inform prevention efforts.Design, Setting, and ParticipantsThis cohort study used a combined analysis of genotyped men without prostate cancer at inclusion and with lifestyle data in 2 prospective cohort studies in Sweden and the US, the Malmö Diet and Cancer Study (MDCS) and the Health Professionals Follow-Up Study (HPFS), followed up from 1991 to 2019. Data were analyzed between April 2023 and April 2024.ExposuresMen were categorized according to modifiable lifestyle behaviors and genetic risk. A polygenic risk score above the median or a family history of cancer defined men at higher genetic risk (67% of the study population); the remaining men were categorized as being at lower genetic risk.Main Outcomes and MeasuresProstate cancer death analyzed using time-to-event analysis estimating hazard ratios (HR), absolute risks, and preventable deaths by age.ResultsAmong the 19 607 men included for analysis, the median (IQR) age at inclusion was 59.0 (53.0-64.7) years (MDCS) and 65.1 (58.0-71.8) years (HPFS). During follow-up, 107 early (by age 75 years) and 337 late (after age 75 years) prostate cancer deaths were observed. Compared with men at lower genetic risk, men at higher genetic risk had increased rates of both early (HR, 3.26; 95% CI, 1.82-5.84) and late (HR, 2.26; 95% CI, 1.70-3.01) prostate cancer death, and higher lifetime risks of prostate cancer death (3.1% vs 1.3% [MDCS] and 2.3% vs 0.6% [HPFS]). Men at higher genetic risk accounted for 94 of 107 early prostate cancer deaths (88%), of which 36% (95% CI, 12%-60%) were estimated to be preventable through adherence to behaviors associated with a healthy lifestyle (not smoking, healthy weight, high physical activity, and a healthy diet).Conclusions and RelevanceIn this 20-year follow-up study, men with a genetic predisposition accounted for the vast majority of early prostate cancer deaths, of which one-third were estimated to be preventable. This suggests that men at increased genetic risk should be targeted in prostate cancer prevention strategies.
Understanding of Endomucin: a Multifaceted Glycoprotein Functionality in Vascular Inflammatory‐Related Diseases, Bone Diseases and Cancers
Authors: Li Xiaoqing , Lv Qing , Liu Peng , Han Guiping , Yu Shan 
Published: July 2024

AbstractEndomucin (MUC14), encoded by EMCN gene, is an O‐glycosylated transmembrane mucin that is mainly found in venous endothelial cells (ECs) and highly expressed in type H vessels of bone tissue. Its main biological functions include promoting endothelial generation and migration through the vascular endothelial growth factor (VEGF) signaling pathway and inhibiting the adhesion of inflammatory cells to ECs. In addition, it induces angiogenesis and promotes bone formation. Due to the excellent functions of Endomucin in the above aspects, it provides a new research target for the treatment of vascular inflammatory‐related diseases and bone diseases. Based on the current understanding of its function, the research of Endomucin mainly focuses on the above two diseases. As it is known, the progression of cancer is closely related to angiogenesis. Endomucin recently is found to be differentially expressed in a variety of tumors and correlated with survival rate. The biological role of Endomucin in cancer is opaque. This article introduces the research progress of Endomucin in vascular inflammatory‐related diseases and bone diseases, discusses its application value and prospect in the treatment, and collects the latest research situation of Endomucin in tumors, to provide meaningful evidence for expanding the research field of Endomucin.
Bioinspired Printable Tough Adhesives with In Situ Benignly Triggered Mechanical Enhancements
Authors: Ma Zhenwei , Huo Ran , Nottegar Alexander , Chung‐Tze‐Cheong Christopher , Gao Qiman , Lan Xiaoyi , Gao Zu‐hua , Li Jianyu 
Published: July 2024

AbstractAdhesives can intimately connect humans to machines, seamlessly bond diverse tissues in the human body, and manage various diseases. However, the precise spatial control of wet and tough adhesion of biocompatible hydrogels on biological tissues remains a major challenge. Inspired by the bioglue secreted by sandcastle worms, the design of printable tough adhesives (PTAs) is proposed, a supramolecular hydrogel that can be printed into defined structures, in situ mechanically reinforced into a tough matrix with physiologically relevant benign triggers, and strongly adhere to diverse substrates. With carefully selected polymer components and ratios, it is discovered that the 3D printed PTAs can achieve a marked increase in toughness, tensile strength, and stiffness after being immersed in water/saline solution or attached to biological tissues. To assess the robust toughening mechanism triggered by the supramolecular interactions, the effects of polymer content and pH on the mechanical performance of PTAs and the kinetics of their triggered reinforcement are thoroughly investigated. The potential of PTAs is further demonstrated for manufacturing tough connective tissue mimetics, controlling patterned bioadhesion, and designing programmable 4D soft robotics. The bioinspired, printable, benignly triggerable, and adhesive supramolecular PTAs are expected to find broad applications in engineering and medicine.
Unprecedented Strength Enhancement Observed in Interpenetrating Phase Composites of Aperiodic Lattice Metamaterials
Authors: Wang Xinxin , Li Zhendong , Deng Junjie , Gao Tianyu , Zeng Kexin , Guo Xiao , Li Xinwei , Zhai Wei , Wang Zhonggang 
Published: July 2024

AbstractSimultaneous high strength and high toughness are highly sought‐after in lattice metamaterials, but these properties are typically mutually exclusive. To overcome this challenge, the development of interpenetrating phase composite (IPC), which incorporates a net matrix infill into the lattice, has shown great potential in overcoming these constraints and is thus of continuous practical interest. In this work, a novel aperiodic monotile truss lattice and polymer IPC that exhibit unprecedented enhancement in both strength and toughness are reported. Specifically, the aperiodic unit cell is inspired by Einstein's monotile, a single space‐filling shape where the cell orientation never repeats. The IPCs are achieved through 3D‐printed Ti‐6Al‐4V truss lattices and epoxy infiltration. The highest gain in compressive strength reveals an impressive 246.61% increase, significantly exceeding the “1 + 1 > 2” idealization typically associated with strength in IPC metamaterials. Furthermore, a high specific energy absorption of 46.2 J g−1 demonstrates superior toughness. The underlying mechanisms, including damage sequences, two‐phase interactions, and geometric effects between truss and epoxy, are fully elucidated. Overall, this work reports unprecedented enhancement in IPC's properties and demonstrates the potential of utilizing idealized structures to achieve an optimal combination of strength and toughness in mechanical metamaterials.
Pb2+ Transfer‐Enabled Recoverable Hydrogel‐Based H2S Colorimetric Sensing with Assistance of Multimodal Deep Learning for Multifunctional Applications
Authors: Chen Yajing , Zhang Dongzhi , Wang Zijian , Tang Mingcong , Zhang Hao 
Published: July 2024

AbstractRecoverable and humidity‐tolerant colorimetric sensors are extremely difficult to overcome. In this work, a composite hydrogel sensor based on chelation reaction is proposed for the first time to achieve ultra‐fast recovery and ultra‐low detection limit (LOD) of H2S colorimetric sensing. The composite hydrogel sensor is constructed by polyvinyl alcohol/boric acid/Pb2+ (PVA/Bn/Pb) hydrogel sensing layer and polyacrylamide/sodium alginate (PAM/SA) hydrogel adsorption layer. The change from white to brown is achieved in H2S and can be restored when placed in the air. The response/recovery mechanism is explained by the transfer of Pb2+ between hydrogels and the formation of an “Alginate‐Pb2+” with egg‐box structure during the process. The multimodal fusion deep neural network (MF‐DNN) can overcome the error caused by hydrogel aging. Due to the excellent loading and diffusion function provided by the 3D structure of hydrogel, the sensor has a broad detection range of 0.2–100 ppm, a response/recovery time of 10s/32s, and a theoretical LOD of 0.026 ppm. A smartphone‐based H2S sensing system is developed to enable non‐invasive halitosis diagnosis, egg freshness detection, and remote H2S monitoring and alarming. The system is recoverable, humidity‐tolerant, capable of ultrafast detection and widely applicable. This work provides inspiration for humidity‐tolerant and recoverable H2S gas sensing.