bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: High ZT in p‐Type (PbTe)1‐2x(PbSe)x(PbS)x Thermoelectric Materials.
Authors: Kanatzidis Mercouri G. , et al. et al. 
Published: June 2014

AbstractPseudoternary Na‐doped (2 at.%) (PbTe)1‐2x(PbSe)x(PbS)x (x: 0.02, 0.05, 0.07, 0.1, and 0.12) compounds are obtained from stoichiometric melts of the elements (evacuated silica tube, 1000 °C, 5 h).
ChemInform Abstract: Tailoring Nanostructures in Micrometer Size Germanium Particles to Improve Their Performance as an Anode for Lithium Ion Batteries.
Authors: Ke Fu‐Sheng , Mishra Kuber , Jamison Lauryn , Peng Xin‐Xing , Ma Shu‐Guo , Huang Ling , Sun Shi‐Gang , Zhou Xiao‐Dong 
Published: June 2014

AbstractA facile and scalable single‐step approach is employed to prepare a bulk Ge electrode material from GeO2 powder by thermal reduction in H2 (300—600 °C, 10 h, 1 bar H2 pressure).
ChemInform Abstract: Li Intercalation into 1D TiS2(en) Chains.
Authors: Li Tianyang , Liu Yi‐Hsin , Chitara Basant , Goldberger Joshua E. 
Published: June 2014

AbstractHybrid organic/inorganic van der Waals solid TiS2(en) is prepared by solvothermal reaction of a sulfur solution in en mixed with a TiCl4 solution in PhCl (Teflon cup in evacuated Parr reactor, 200—220 °C, 5 d) followed by purification via repeated recrystallization of the gel‐like product and centrifugation.
ChemInform Abstract: General Strategy for Zero‐Valent Intercalation into Two‐Dimensional Layered Nanomaterials.
Authors: Motter Janina P. , Koski Kristie J. , Cui Yi 
Published: June 2014

AbstractHigh densities of copper (up to 55 at.%) are intercalated into two‐dimensional nanomaterials such as MoO3, Sb2O3, In2Se3, and GaSe leading to Cu0.12MoO3, Cu0.88Sb2O3, Cu2.14In2Se3, and Cu2.34GaSe, respectively.
ChemInform Abstract: Synthesis, Crystal Structure, and Electronic Properties of the CaRE3SbO4 and Ca2RE8Sb3O10 Phases (RE = Rare‐Earth Metal).
Authors: Forbes Scott , Yuan Fang , Saparov Bayrammurad , Sefat Athena S. , Kosuda Kosuke , Kolodiazhnyi Taras , Mozharivskyj Yurij 
Published: June 2014

AbstractThe new phases CaLn3SbO4 (Ln: Ce—Nd, Sm—Dy) and Ca2Ln8Sb3O10 (Ln: La—Nd, Sm—Dy) are prepared from stoichiometric amounts of CaO, Ln2O3, and LnSb (Ta ampules, induction furnace, 1300—1600 °C, 5 h).
ChemInform Abstract: High‐Pressure Synthesis, Crystal Structure, and Phase Stability Relations of a LiNbO3‐Type Polar Titanate ZnTiO3 and Its Reinforced Polarity by the Second‐Order Jahn—Teller Effect.
Authors: Inaguma Yoshiyuki , Aimi Akihisa , Shirako Yuichi , Sakurai Daichi , Mori Daisuke , Kojitani Hiroshi , Akaogi Masaki , Nakayama Masanobu 
Published: June 2014

AbstractPolar ZnTiO3 with LiNbO3‐type structure (LN‐type) is prepared from ilmenite‐type ZnTiO3 (multianvil press, 1000 °C, 7.5 GPa, 30 min).
ChemInform Abstract: Preparation and Redox Studies of α1‐ and α2‐Isomers of Mono‐Ru‐Substituted Dawson‐Type Phosphotungstates with a DMSO Ligand: [α1/α2‐P2W17 O61RuII(DMSO)]8—.
Authors: Ogo Shuhei , Shimizu Noriko , Nishiki Kensuke , Yasuda Nobuhiro , Mizuta Tsutomu , Sano Tsuneji , Sadakane Masahiro 
Published: June 2014

AbstractBoth α1‐ and α2‐isomers of mono‐Ru‐substituted Dawson‐type heteropolytungstates with DMSO as ligands are isolated in pure form and characterized by single crystal XRD, IR, NMR, and UV/VIS spectroscopy, mass spectrometry, and cyclic voltammetry.
ChemInform Abstract: Regio‐Controlled Pentadienylation of Sulfinylimines by Pentadienyltin Reagent. Efficient Lewis Acid Activation of 4‐Methoxyphenylsulfinyl Imines.
Authors: Nishigaichi Yutaka , Tsuruta Shinji , Uenaga Kenji , Awamura Tomohiko , Iwamoto Hidetoshi , Takuwa Akio 
Published: June 2014

AbstractIn the presence of TmsOTf mainly ε‐adducts are obtained whereas InCl3 gives the corresponding γ‐adducts.
ChemInform Abstract: Rh(III)‐Catalyzed Intramolecular Redox‐Neutral Cyclization of Alkenes via C—H Activation
Authors: Shi Zhuangzhi , Boultadakis‐Arapinis Melissa , Koester Dennis C. , Glorius Frank 
Published: June 2014

Abstractleading to a variety of fused multicyclic lactams of biological interest
ChemInform Abstract: Copper‐Catalyzed Redox‐Neutral C—H Amination with Amidoximes.
Authors: Chen Hui , Chiba Shunsuke 
Published: June 2014

AbstractDihydroimidazoles (II) and (IV) are formed via sp3 C—H amination of N‐alkylamidoximes (I) and (III).
ChemInform Abstract: An Improved Protocol for Regioselective Ring‐Opening of Sulfonyl Aziridines with Iodine Promoted by PPh3.
Authors: Zhang Jinfeng , Meng Lingguo , Li Chuntao , Xiao Guoyuan 
Published: June 2014

AbstractA new route for the synthesis of β‐iodoamines (II) via a highly efficient and chemoselective ring opening of aziridines with iodine is developed.
ChemInform Abstract: Methodology for in situ Protection of Aldehydes and Ketones Using Trimethylsilyl Trifluoromethanesulfonate and Phosphines: Selective Alkylation and Reduction of Ketones, Esters, Amides, and Nitriles.
Authors: Yahata Kenzo , Minami Masaki , Yoshikawa Yuki , Watanabe Kei , Fujioka Hiromichi 
Published: June 2014

AbstractA new methodology for the selective reduction and alkylation of carbonyl nitrile groups in substrates also bearing more reactive aldehyde or ketone moieties is developed.
ChemInform Abstract: Formal Hydration of Non‐activated Terminal Olefins Using Tandem Catalysts.
Authors: Yang Yongsheng , Guo Jiayi , Ng Huimin , Chen Zhiyong , Teo Peili 
Published: June 2014

AbstractA tandem Pd(II)/Ru(II) catalyst system allows for the highly regioselective hydration of a broad range of olefins, including substituted styrenes and aliphatic olefins with various functional groups.
ChemInform Abstract: Stereoselective Titanium‐Mediated Aldol Reactions of a Chiral Lactate‐Derived Ethyl Ketone with Ketones.
Authors: Alcoberro Sandra , Gomez‐Palomino Alejandro , Sola Ricard , Romea Pedro , Urpi Felix , Font‐Bardia Merce 
Published: June 2014

AbstractThe title reaction proceeds in a very efficient and stereocontrolled manner provided that a further equivalent of TiCl4 is added to the reacting mixture.
ChemInform Abstract: A Practical Route for the Highly Stereoselective Synthesis of Tetrasubstituted Fluoroalkenes.
Authors: Cao Chun‐Ru , Ou Song , Jiang Min , Liu Jin‐Tao 
Published: June 2014

AbstractInstead of the benzothiazole‐2‐sulfonyl (Btz) group a phenyl‐1H‐tetrazole‐5‐sulfonyl group can be used as the leaving group for the olefination reaction as well.
ChemInform Abstract: “Sulfolefin”: A Mixed Sulfinamido‐Olefin Ligand in Enantioselective Rhodium‐Catalyzed Addition of Arylboronic Acids to Trifluoromethyl Ketones.
Authors: Valdivia Victoria , Fernandez Inmaculada , Khiar Noureddine 
Published: June 2014

AbstractRh‐catalyzed enantioselective arylation of trifluoromethyl ketones with arylboronic acids is achieved by employing a chiral sulfinamido‐olefin ligand.
ChemInform Abstract: Selective Copper(II)‐Catalyzed Aerobic Oxidative Cleavage of Aromatic gem‐Disubstituted Alkenes to Carbonyl Compounds under Neutral and Mild Conditions.
Authors: Hossain Md. Munkir , Shyu Shin‐Guang 
Published: June 2014

AbstractThe process involves the formation of 2‐hydroperoxytetrahydrofuran which is proposed to be the real oxidant in the alkane cleavage reaction.
ChemInform Abstract: Alkylation/Elimination from Azetidinium Ylides: An Entry to Functionalized Acrylonitriles.
Authors: Lo Cheikh , David Olivier , Couty Francois 
Published: June 2014

AbstractA one‐pot two‐step sequence for the synthesis of acrylonitriles involving alkylation of azetidinium ylides followed by regioselective Hofmann elimination is developed.
ChemInform Abstract: Copper‐Catalyzed Chan—Lam Coupling Between Sulfonyl Azides and Boronic Acids at Room Temperature.
Authors: Moon Soo‐Yeon , Nam Jungsoo , Rathwell Kris , Kim Won‐Suk 
Published: June 2014

AbstractAn efficient coupling of a variety of sulfonyl azides with arylboronic acids proceeds in the presence of CuCl as catalyst and gives generally good yields of the corresponding N‐aryl sulfonamides.
ChemInform Abstract: Ruthenium‐Catalyzed ortho‐Arylation of Acetanilides with Aromatic Boronic Acids: An Easy Route to Prepare Phenanthridines and Carbazoles.
Authors: Chinnagolla Ravi Kiran , Jeganmohan Masilamani 
Published: June 2014

AbstractA wide range of ortho‐arylated acetanilides is prepared tolerating various functional groups.
ChemInform Abstract: Synthesis and Properties of 6‐Methoxy‐ and 6‐Dimethylamino‐1‐methylthio‐ and 1,3‐Bis(methylthio)azulenes and Triflic Anhydride‐Mediated Synthesis of Their Biaryl Derivatives.
Authors: Shoji Taku , Maruyama Akifumi , Maruyama Mitsuhisa , Ito Shunji , Okujima Tetsuo , Higashi Junya , Toyota Kozo , Morita Noboru 
Published: June 2014

AbstractThe synthesis of 1‐methylthio‐ and 1,3‐bis(methylthio)azulenes with an electron‐donating group at the 6‐position as well as their transformation into the corresponding novel 1,1′‐bisazulene derivatives [cf.
ChemInform Abstract: Transalkylation of Higher Trifluoromethylated Fullerenes with C70: A Pathway to New Addition Patterns of C70(CF3)8.
Authors: Belov Nikita M. , Apenova Marina G. , Rybalchenko Alexey V. , Borkovskaya Eugenia V. , Lukonina Natalia S. , Goryunkov Alexey A. , Ioffe Ilya N. , Troyanov Sergey I. , Sidorov Lev N. 
Published: June 2014

AbstractThree novel isomers of C70(CF3)8, which are structurally related to p7mp‐C70(CF3)10, are isolated by the title reaction.
ChemInform Abstract: N‐Benzoyl‐ and Arenesulfonylimines of Methyl Trifluoropyruvate in the Cyclocondensation Reaction with Acetylacetone.
Authors: Sokolov V. B. , Aksinenko A. Yu. , Epishina T. A. , Goreva T. V. , Martynov I. V. 
Published: June 2014

AbstractEt3N‐catalyzed cyclocondensation of imines (I) with acetylacetone provides dihydrofuranones (III) in good yields.
ChemInform Abstract: Pd‐Catalyzed Oxidative Coupling of Enamides and Alkynes for Synthesis of Substituted Pyrroles.
Authors: Zhao Mi‐Na , Ren Zhi‐Hui , Wang Yao‐Yu , Guan Zheng‐Hui 
Published: June 2014

AbstractThe method is only applicable to aryl‐substituted enamides, whereas aliphatic ones do not react.
ChemInform Abstract: Versatile Oxidative Approach to Carbazoles and Related Compounds Using MoCl5.
Authors: Trosien Simon , Boettger Philipp , Waldvogel Siegfried R. 
Published: June 2014

AbstractOxidative intramolecular coupling of tertiary amines with at least two electron‐rich arenes gives carbazoles in good to excellent yields.
ChemInform Abstract: Transition‐Metal‐Free Synthesis of N‐(1‐Alkenyl)imidazoles by Potassium Phosphate‐Promoted Addition Reaction of Alkynes to Imidazoles.
Authors: Lu Linhua , Yan Hong , Liu Defu , Rong Guangwei , Mao Jincheng 
Published: June 2014

AbstractIn contrast to the examined heterocyclic amines, aliphatic amines such as morpholine and diisopropylamine as well as aniline do not react under the investigated conditions.
ChemInform Abstract: An Unprecedented Ring Transformation of a 4‐(Aminomethyl)oxazoline Derivative to a 4‐(Hydroxymethyl)imidazoline.
Authors: Schulz Marvin , Christoffers Jens 
Published: June 2014

AbstractAn optically active 4‐(azidomethyl)‐2‐(2‐pyridyl)oxazoline (III) is prepared starting from L‐serine methyl ester and picolinic acid via a 7‐step sequence.
ChemInform Abstract: N‐Heterocyclic Carbene Catalyzed Reaction of 2‐(2‐Aroylvinyl)cinnamaldehydes with α,β‐Unsaturated Imines: An Efficient Method for the Stereoselective Synthesis of Highly Functionalized Indane Derivatives.
Authors: Tang Ming‐Sheng , Zhao Yuan , Cheng Ying 
Published: June 2014

AbstractThe title reaction yields indenopyranones (III) and (VI) in good yields and with high diastereoselectivity.
ChemInform Abstract: Silyl‐Protected Dioxaborinanes: Application in the Suzuki Cross‐Coupling Reaction.
Authors: Goggins Sean , Rosevere Eleanor , Bellini Clement , Allen Joseph C. , Marsh Barrie J. , Mahon Mary F. , Frost Christopher G. 
Published: June 2014

AbstractThe synthesis of a wide range of column‐ and bench‐stable silyl‐protected dioxaborinanes (IV) is reported.
ChemInform Abstract: Rapid Access to α‐Carbolines via a One‐Pot Tandem Reaction of α,β‐Unsaturated Ketones with 2‐Nitrophenylacetonitrile and the anti‐Proliferative Activities of the Products.
Authors: Zhang Xiaofei , He Qian , Xiang Haoyue , Song Shanshan , Miao Zehong , Yang Chunhao 
Published: June 2014

AbstractA variety of α‐carbolines is readily prepared by reaction of 2‐nitrophenylacetonitrile with chromones (I) or benzylidene acetones (VI).
ChemInform Abstract: Cross‐Coupling of 2,5‐Bis(chloromethylidene)‐1,4‐dithiane with Phenylacetylene as an Example of Preparation of Symmetric Bridging Bisenyne Compounds.
Authors: Martynov A. V. , Makhaeva N. A. , Amosova S. V. 
Published: June 2014

AbstractBisenyne (III) is obtained with complete E,E‐selectivity.
ChemInform Abstract: Metal‐Free Regioselective C—C Bond Cleavage in 1,3,5‐Triazine Derivatives of β‐Diketones.
Authors: Kopylovich Maximilian N. , Mahmudov Kamran T. , Haukka Matti , Pombeiro Armando J. L. 
Published: June 2014

AbstractThe reaction of cyanuric chloride (I) with 3 equivalents of ketones (II) in the presence of 3 equivalents of KOH affords adducts (IV), which are converted into deacylated derivatives (III) by treatment with aqueous HCl solution in MeOH.
ChemInform Abstract: A New and Efficient Route for the Synthesis of Alkynyl Functionalized Silicon Derivatives.
Authors: Kownacki Ireneusz , Orwat Bartosz , Marciniec Bogdan , Kownacka Agnieszka 
Published: June 2014

AbstractThe iridium catalyzed coupling of terminal alkynes with iodosilanes gives various arylethynylene substituted silicon derivatives including products containing reactive functional groups such as (IIIc) and (IIId).
ChemInform Abstract: Heterogeneous Reusable Catalyst, Ultrasound Energy, and No Solvent: A Quick and Green Recipe for One‐Pot Synthesis of β‐Phosphonomalononitriles at Room Temperature.
Authors: Dar Bashir Ahmad , Pandey Nalini , Singh Snehil , Bamezai R. K. , Sharma Meena , Vishwakarma Ram A. , Singh Baldev 
Published: June 2014

AbstractReplacement of aldehydes (I) by ketones or of malonitrile (II) by malonate derivatives yields the corresponding products only in trace amounts.
ChemInform Abstract: Isolation, Characterization, and NMR Spectroscopic Data of Indole and Oxindole Alkaloids from Mitragyna speciosa.
Authors: Ali Zulfiqar , Demiray Hatice , Khan Ikhlas A. 
Published: June 2014

AbstractThe new alkaloids, 7β‐hydroxy‐7H‐mitraciliatine (I) and isospecciofoleine (II), are isolated and characterized together with nine known alkaloids.
ChemInform Abstract: Nickel‐Catalyzed Dimerization of Pyrrolidinoindoline Scaffolds: Systematic Access to Chimonanthines, Folicanthines and (+)‐WIN 64821.
Authors: Wada Mitsuhiro , Murata Takahisa , Oikawa Hideaki , Oguri Hiroki 
Published: June 2014

AbstractAn alternative catalytic protocol for the dimerization of tertiary alkyl bromides using manganese as reductant is developed and applied to the total synthesis of dimeric alkaloids such as chimonanthine (V), folicanthine (VI) and the potent substance P antagonist (+)‐WIN 64821 (IX) is also reported.
ChemInform Abstract: Transition‐Metal‐Catalyzed Carbonylation Reactions of Olefins and Alkynes: A Personal Account
Authors: Wu Xiao‐Feng , Fang Xianjie , Wu Lipeng , Jackstell Ralf , Neumann Helfried , Beller Matthias 
Published: June 2014

AbstractReview: 46 refs.
ChemInform Abstract: Diastereo‐ and Enantioselective anti‐Selective Hydrogenation of α‐Amino‐β‐keto Ester Hydrochlorides and Related Compounds Using Transition‐Metal‐Chiral‐Bisphosphine Catalysts
Authors: Hamada Yasumasa 
Published: June 2014

AbstractReview: [28 refs.
ChemInform Abstract: The Use of Lipases as Biocatalysts for the Epoxidation of Fatty Acids and Phenolic Compounds
Authors: Aouf Chahinez , Durand Erwann , Lecomte Jerome , Figueroa‐Espinoza Maria‐Cruz , Dubreucq Eric , Fulcrand Helene , Villeneuve Pierre 
Published: June 2014

AbstractReview: 159 refs.
Eine Einführung in die Quantenchemie
Authors: Jansen Georg 
Published: June 2014

AbstractIn der Quantenchemie wird die grundlegende physikalische Theorie der Quantenmechanik zur quantitativen Beschreibung chemischer Substanzen und ihrer Reaktionen angewendet. Eine klare Aufgabe – aber nicht ganz so leicht umzusetzen. Der Artikel geht zunächst auf einige Aspekte der Quantenmechanik ein, die exotisch scheinen mögen, in der Welt der Elektronen und Atomkerne aber normal sind. Er diskutiert dann eine Reihe grundlegender Näherungen, mit deren Hilfe wir uns in dieser Welt zurecht finden können. Schließlich deutet der Artikel gelegentlich an, wie daraus in Computerprogramme implementierte quantenchemische Methoden entstehen, deren Resultate beim Verstehen und der Vorhersage der Eigenschaften und des Verhaltens chemischer Systeme helfen.
Raffinose + Raffinase = Raffinade: Raffiniert!
Authors: Winkler Markus , Steinke Katrin , Oehme Ramona , Berger Stefan , Sicker Dieter , Siehl Hans‐Ullrich , Zeller Klaus‐Peter 
Published: June 2014

AbstractRaffinose wurde aus den Samen der Blauen Süßlupine durch Extraktion mit 50% Ethanol gewonnen und über eine Kationen‐Austauschersäule sowie schließlich durch analytische HPLC mit Hilfe eines RI‐Detektors gereinigt. Alle analytischen Spektren sind vollständig entweder im Hauptteil oder in der supporting information wiedergegeben. Die NMR‐ sowie die Massenspektren werden eingehend interpretiert und mit theoretischen Berechnungen der 13C chemischen Verschiebungen verglichen. Das Projekt stellt eine Fortsetzung des Buches “Classics in Spectroscopy” von S. Berger und D. Sicker (Wiley‐VCH 2009) dar.
75 Jahre DDT
Authors: Hübner Karl 
Published: June 2014

AbstractFluch und Segen liegen manchmal eng beieinander. In der chemischen Industrie kennt man diese Nähe nur zu gut. Die Branche hat manches hervorgebracht, was für die einen Triumphe menschlicher Genialität mit großem Nutzen für die Menschheit schien, für Teile dieser Menschheit aber zum Gegenstand unversöhnlichen Hasses wurde.
Marihuana‐Medizin macht Ernst
Authors: Groß Michael 
Published: June 2014

AbstractLegale Cannabis‐Produkte für medizinische Zwecke sind auf dem Vormarsch, und auch der Joint als Freizeitvergnügen wurde mancherorts bereits legalisiert. Für analytische Laboratorien eröffnet sich ein neuer Markt in der Qualitätskontrolle von Cannabisprodukten.
Chemie, die uns guttut
Authors: Harrer Roswitha 
Published: June 2014

AbstractDer Löwenanteil der Produktion von Superabsorbern geht in die Windelindustrie. Kaum jemand kann sich mehr vorstellen, auf diese bequemen Einmalartikel zu verzichten. Auch Hygieneartikel für Frauen und Inkontinenzprodukte funktionieren auf der chemischen Basis von Superabsorbern, und sie sind ein stetig wachsender Markt. Es geht um diskrete Hygiene mit Hilfe eines chemischen Produkts: Superabsorber tun gut.
The effects of word‐of‐mouth consistency on persuasiveness
Authors: Chang Sue‐Ting , Lin Tom M. Y. , Luarn Pin 
Published: June 2014

AbstractWord of mouth (WOM) consistency can be readily observed in online product evaluations. Previous studies on the influence of WOM consistency on purchase intentions have showed contradictory results. In this research, we identify how stronger persuasiveness of WOM is achieved when consistency, product type, and review content work together. Study 1 shows that regarding search goods, highly consistent factual reviews are more persuasive. Study 2 shows that concerning experience goods and credence goods, highly consistent experiential reviews have greater persuasiveness. However, low WOM consistency can also achieve stronger persuasiveness under some circumstances. Moreover, in Study 3, we replicate our findings and explore the possible underlying mechanism. Copyright © 2014 ASAC. Published by John Wiley & Sons, Ltd.
The subjective valuation of coins and bills
Authors: Dolansky Eric 
Published: June 2014

AbstractThere is more to how individuals value money than just the denomination, based on several recent research articles. Could the very form of money, whether paper or metal, be a basis for such subjective valuation? A theoretical explanation based on the representativeness bias is explored and three experimental studies are employed to investigate this question. The results show that there is a bias in how the value of money is assessed based on whether that money is comprised of coins or bills. Bills are estimated to have more purchasing power than coins for the same objects, including for a different currency where a specific exchange rate is given. Copyright © 2014 ASAC. Published by John Wiley & Sons, Ltd.
Impact on abiraterone pharmacokinetics and safety: Open‐label drug–drug interaction studies with ketoconazole and rifampicin
Authors: Bernard Apexa , Vaccaro Nicole , Acharya Milin , Jiao James , Monbaliu Johan , De Vries Ronald , Stieltjes Hans , Yu Margaret , Tran Namphuong , Chien Caly 
Published: June 2014

AbstractWe evaluated the impact of a strong CYP3A4 inhibitor, ketoconazole, and a strong inducer, rifampicin, on the pharmacokinetic (PK) exposure of abiraterone in two studies in healthy men. All subjects received 1,000 mg of abiraterone acetate on Days 1 and 14. Study A subjects (n = 20) received 400 mg ketoconazole on Days 11–16. Study B subjects (n = 19) received 600 mg rifampicin on Days 8–13. Serial PK sampling was done on Days 1 and 14. Study A: When given with ketoconazole, abiraterone exposure increased by 9% for maximum plasma concentration (Cmax) and 15% for area under the plasma concentration–time curve from 0 to time of the last quantifiable concentration (AUClast) and AUC from time 0 to infinity (AUC∞) compared to abiraterone acetate alone. Study B: When given with rifampicin, abiraterone exposure was reduced to 45% for Cmax and AUC∞ and to 42% for AUClast compared to abiraterone acetate alone. Ketoconazole had no clinically meaningful impact on abiraterone exposure. Rifampicin decreased abiraterone exposure by half. Hence, strong CYP3A4 inducers should be avoided or used with careful evaluation of clinical efficacy when administered with abiraterone acetate.
The Local Kinetic Energy Profile of an Inverted CarbonCarbon Bond Reveals and Refines its Charge‐Shift Character
Authors: Jacobsen Heiko 
Published: June 2014

AbstractAnalysis of the kinetic energy density within a molecule identifies patterns in its electronic structure that are linked to the concept of charge‐shift bonding. This is illustrated in a detailed study of twelve molecules, possessing carbon‐carbon covalent as well as carbon‐carbon charge‐shift bonds in various degrees of orders, including propellanes and heteropropellanes. Regions of slow electrons are fundamental for such a correlation, and a RoSE (region of slow electrons) indicator ν±, based on the positive definite kinetic energy density τ, is employed to characterize classes of charge‐shift bonds in terms of its full topology of all critical points of rank three.