bluuebunny/crossref_metadata_2025_split huggingface dataset:
Seasonal and diurnal cycles of liquid water in snow—Measurements and modeling
Authors: Heilig A. , Mitterer C. , Schmid L. , Wever N. , Schweizer J. , Marshall H.‐P. , Eisen O. 
Published: September 2015

AbstractEvaluating and improving snow models and outflow predictions for hydrological applications is hindered by the lack of continuous data on bulk volumetric liquid water content (θw) and storage capacity of the melting snowpack. The combination of upward looking ground‐penetrating radar and conventional snow height sensors enable continuous, nondestructive determinations of θw in natural snow covers from first surficial wetting until shortly before melt out. We analyze diurnal and seasonal cycles of θw for 4 years in a flat study site and for three melt seasons on slopes and evaluate model simulations for two different water transport schemes in the snow cover model SNOWPACK. Observed maximum increases in θw during a day are below 1.7 vol % (90th percentile) at the flat site. Concerning seasonal characteristics of θw, less than 10% of recorded data exceed 5 vol % at the flat site and 3.5 vol % at slopes. Both water transport schemes in SNOWPACK underestimate maximum θw at the flat site systematically for all observed melt seasons, while simulated θw maxima on slopes are accurate. Implementing observed changes in θw per day in outflow predictions increases model performance toward higher agreement with lysimeter measurements. Hence, continuously monitoring θw improves our understanding of liquid water percolation and retention in snow, which is highly relevant for several aspects of the cryosphere such as avalanche formation, catchment hydrology, and ice sheet mass balances.
Synthesis of lysozyme imprinted column with macroporous structure and enhanced selectivity: Utilization of cryogelation technique and electrostatic functional monomers
Authors: Kashefi Mofrad Seyed Mohammad Reza , Naeimpoor Fereshteh , Hejazi Parisa , Nematollahzadeh Ali 
Published: September 2015

ABSTRACTApplicability of molecularly imprinted polymers (MIP) in conventional protein separation processes demands monolithic construction of columns with macroporous structure in addition to the high specificity and adsorption capacity. In this study, therefore, lysozyme (Lyz) imprinted monolithic cryogel columns were synthesized using electrostatic functional monomers (EFMs) to provide strong interactions between template and polymer, leading to specific recognition and capture of Lyz. SEM images and FTIR spectroscopy analysis confirmed the macroporous structure and presence of EFMs in the samples. Adsorption isotherms, heterogeneity, and breakthrough curves as well as selectivity of the molecularly imprinted cryogels (EFMs‐MIC) and non‐imprinted cryogels (EFMs‐NIC) were investigated. Results showed effective imprinting with a maximum adsorption capacity of 211 mg/g and a high imprinting factor (IF) of 4.2 at low Lyz concentrations. A high relative selectivity coefficient of 7.24 was obtained for Lyz over cytochrome c, a competing protein, indicating that the imprinted sites could well distinguish Lyz. Reusability of MICs was also examined, where insignificant changes were observed in the cryogel adsorption/desorption characteristics after four cycles. Therefore, it is suggested to use EFMs and cryogelation in the synthesis of imprinted monolithic cryogels column for application in conventional protein separation processes. © 2015 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2016, 133, 42880.
Light‐diffusing materials for LED illumination applications: Comparing the effectiveness of two typical light‐diffusing agents
Authors: Ouyang Xing , Li Peibin , Chen Dazhu , Tang Jiaoning 
Published: September 2015

ABSTRACTLight‐diffusing materials (LDMs) are the primary lampshade materials used for indoor light‐emitting diode (LED) illumination. In this work, two varieties of typical LDMs filled with acrylic or silicone diffusing agents were fabricated via a twin‐screw extruder, and the influences of the particle size, refractive index and light‐diffusing surface area of the light‐diffusing agents on the properties of the LDMs, including their light‐diffusing properties, thermal stability and mechanical properties, were explored in depth. The results indicated that both acrylic and silicone light‐diffusing agents can be dispersed evenly in a polycarbonate (PC) matrix. The light‐diffusing surface area and refractive index are the main factors that influence the diffusing properties of LDMs. Compared with the silicone LDM, the acrylic LDM exhibited higher transmittance but poorer thermal stability and impact strength, making this material suitable for a rapid injection molding process to form half‐sphere covers that combine high haze and transmittance for LED light bulbs. Silicone LDMs exhibit good stability and impact strength, favoring a slow single‐screw extrusion molding process to prepare tubular or panel covers for tubular LED lamps and panel lamps. In this study, a method for producing LDMs with both high transmittance and high haze is reported. © 2015 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2016, 133, 42923.
Neurochemical Features of the Autonomic Neurons Projecting to the Cremaster Muscle of the Boar
Authors: Botti Maddalena , Ragionieri Luisa , Cacchioli Antonio , Gazza Ferdinando , Panu Rino 
Published: September 2015

ABSTRACTThe cremaster muscle (CM) is a striated muscle showing some unusual features for ordinary striated muscles, in fact it receives, besides somatic innervation, a conspicuous autonomic sympathetic innervation. The autonomic neurons associated with the CM of 4 male intact pigs were typified combining the retrograde nontrans‐synaptic fluorescent tracer Fast Blue (FB) and double labeling immunohistochemical methods. We collected the L4 sympathetic trunk ganglion (STG), that our preliminary studies proved to contain the highest number (575.5 ± 152.93; mean ± S.E.M., n = 4) of FB+ sympathetic neurons projecting to CM. About half of the CM projecting neurons of this ganglion were catecholaminergic and showed the colocalization of Tyrosine Hydroxylase (TH) with Neuropeptide Y (NPY), Leu‐Enkephaline (LENK), Vasoactive Intestinal Polypeptide (VIP), Calcitonine Gene Related Peptide (CGRP), Substance P (SP), neuronal Nitric Oxyde Sinthase (n‐NOS), and Vesicular Acetylcholine Transporter (VAChT). The noncatecholaminergic neurons were immunoreactive for all the other markers tested, even if in small percentages. The conspicuous and heterogeneous contribution of the sympathetic autonomic neurons to the muscle innervation is consistent with the hypothesis of a possible origin of the CM fibers by transdifferentiation of the smooth muscle‐like gubernaculum mesenchyma into striated myotubes, suggesting that the cremaster myogenesis is independent from that of the abdominal muscles. Anat Rec, 298:2091–2097, 2015. © 2015 Wiley Periodicals, Inc.
Garcinol downregulates Notch1 signaling via modulating miR‐200c and suppresses oncogenic properties of PANC‐1 cancer stem‐like cells
Authors: Huang Chi‐Cheng , Lin Chien‐Min , Huang Yan‐Jiun , Wei Li , Ting Lei‐Li , Kuo Chia‐Chun , Hsu Cheyu , Chiou Jeng‐Fong , Wu Alexander T. H. , Lee Wei‐Hwa 
Published: September 2015

AbstractPancreatic cancer represents one of the most aggressive types of malignancy due to its high resistance toward most clinically available treatments. The presence of pancreatic cancer stem‐like cells (CSCs) has been attributed to the intrinsically high resistance and highly metastatic potential of this disease. Here, we identified and isolated pancreatic CSCs using the side population (SP) method from human pancreatic cancer cell line, PANC‐1. We then compared the SP and non‐SP PANC‐1 cells genetically. PANC‐1 SP cells exhibited CSC properties including enhanced self‐renewal ability, increased metastatic potential, and resistance toward gemcitabine treatment. These cancer stem‐like phenotypes were supported by their enhanced expression of ABCG2, Oct4, and CD44. A traditional plant‐derived antioxidant, garcinol, has been implicated for its anticancer properties. Here, we found that garcinol treatment to PANC‐1 SP cells significantly suppressed the stem‐like properties of PANC‐1 SP cells and metastatic potential by downregulating the expression of Mcl‐1, EZH2, ABCG2, Gli‐1, and Notch1. More importantly, garcinol treatment led to the upregulation of several tumor suppressor microRNAs, and miR‐200c increased by garcinol treatment was found to target and downregulate Notch1. Thus, PANC‐1 SP cells may serve as a model for studying drug‐resistant pancreatic CSCs, and garcinol has the potential as an antagonist against pancreatic CSCs.
Characterization of paliperidone photodegradation products by LC‐Q‐TOF multistage mass spectrometry
Authors: Skibiński Robert , Komsta Łukasz , Inglot Tadeusz 
Published: September 2015

AbstractThe photodegradation of paliperidone in aqueous and methanol media under UVA and UVC irradiation was investigated. The identification and structural elucidation of its photodegradation products were performed by the use of the reversed‐phase liquid chromatography coupled with accurate mass hybrid Q‐TOF mass spectrometry and an atmospheric pressure chemical ionization source. Five degradation products were found and their masses were obtained with high accuracy (1.10–5.26 ppm) based on the TOF (MS) spectra. For the structural elucidation of unknown degradation products MS/MS spectra were also registered. However, for the identification of the main photodegradation product (3‐{2‐[4‐(6‐fluoro‐1,3‐benzoxazol‐2‐yl)piperidin‐1‐yl]ethyl}‐9‐hydroxy‐2‐methyl‐6,7,8,9‐tetrahydro‐4H‐pyrido[1,2‐a]pyrimidin‐4‐one) in‐source fragmentation connected with collision‐induced dissociation was used and MS3 spectra were finally performed. The photodegradation of paliperidone yields the first‐order kinetics in all tested conditions. The aqueous medium was in this case much less stable than the methanol solvent regardless of the irradiation source. Additionally, the toxicity of the analyzed photodegradation products was predicted by the use of ECOSAR software and comparable values of LC50 for the main degradants and the parent compound were obtained. Copyright © 2015 John Wiley & Sons, Ltd.
Accelerating sample preparation through enzyme‐assisted microfiltration of Salmonella in chicken extract
Authors: Vibbert Hunter B. , Ku Seockmo , Li Xuan , Liu Xingya , Ximenes Eduardo , Kreke Thomas , Ladisch Michael R. , Deering Amanda J. , Gehring Andrew G. 
Published: September 2015

Microfiltration of chicken extracts has the potential to significantly decrease the time required to detect Salmonella, as long as the extract can be efficiently filtered and the pathogenic microorganisms kept in a viable state during this process. We present conditions that enable microfiltration by adding endopeptidase from Bacillus amyloliquefaciens to chicken extracts or chicken rinse, prior to microfiltration with fluid flow on both retentate and permeate sides of 0.2 μm cutoff polysulfone and polyethersulfone hollow fiber membranes. After treatment with this protease, the distribution of micron, submicron, and nanometer particles in chicken extracts changes so that the size of the remaining particles corresponds to 0.4–1 μm. Together with alteration of dissolved proteins, this change helps to explain how membrane fouling might be minimized because the potential foulants are significantly smaller or larger than the membrane pore size. At the same time, we found that the presence of protein protects Salmonella from protease action, thus maintaining cell viability. Concentration and recovery of 1–10 CFU Salmonella/mL from 400 mL chicken rinse is possible in less than 4 h, with the microfiltration step requiring less than 25 min at fluxes of 0.028–0.32 mL/cm2 min. The entire procedure—from sample processing to detection by polymerase chain reaction—is completed in 8 h. © 2015 American Institute of Chemical Engineers Biotechnol. Prog., 31:1551–1562, 2015
ChemInform Abstract: Structural, Elastic, Electronic, Bonding, and Optical Properties of BeAZ2 (A: Si, Ge, Sn; Z: P, As) Chalcopyrites
Authors: Fahad Shah , Murtaza G. , Ouahrani T. , Khenata R. , Yousaf Masood , Omran S.Bin , Mohammad Saleh 
Published: September 2015

AbstractDFT calculations
ChemInform Abstract: Infinitely Adaptive Transition‐Metal Ordering in Ln2O2MSe2‐Type Oxychalcogenides.
Authors: Ainsworth Chris M. , Wang Chun‐Hai , Johnston Hannah E. , McCabe Emma E. , Tucker Matthew G. , Brand Helen E. A. , Evans John S. O. 
Published: September 2015

AbstractA range of Ln2O2M11‐xM 2xSe2 and La2‐yCeyO2M1Se2 (Ln: La, Ce, M1/M2: Fe, Zn, Mn, Cd) solid solutions are prepared (60 new compositions) to investigate the effects of systematically changing the relative sizes of [Ln2O2]2+ and [MSe2]2‐ layers on transition metal ordering by powder X‐ray and neutron diffraction.
ChemInform Abstract: A Linear Bridging Angle in the Pyrovanadate Group within the Crystal Structure of Hg2V2Te2O11.
Authors: Weil Matthias 
Published: September 2015

AbstractHg2V2Te2O11 single crystals are hydrothermally grown from a 1:1:1 molar mixture of HgO, TeO2, and NH4VO3 (autoclave, 473 K, 1 week).
ChemInform Abstract: Novel Mixed Cobalt/Chromium Phosphate NaCoCr2(PO4)3 Showing Spin‐Flop Transition.
Authors: Souiwa Khalifa , Chennabasappa Madhu , Decourt Rodolphe , Ben Amara Mongi , Hidouri Mourad , Toulemonde Olivier 
Published: September 2015

AbstractThe new title compound is prepared by solid state reaction of a stoichiometric mixture of Na2CO3, Co(NO3)2, Cr(NO3)3, and (NH4)H2PO4 (Pt crucible, 1423 K, 48 h).
ChemInform Abstract: Ambient‐Pressure Synthesis of Two New Vanadium‐Based Calcium Ferrite‐Type Compounds: NaV1.25Ti0.75O4 and NaVSnO4.
Authors: Viciu Liliana , Ryser Alice , Mensing Christian , Bos Jan‐Willem G. 
Published: September 2015

AbstractThe title compounds are synthesized (0.5 g scale) at ambient pressure using Na2CO3, V2O3, TiO2, and SnO2 as starting materials (2 d at 650 °C followed by 3 d at 700—750 °C).
ChemInform Abstract: Gold‐Catalyzed Oxime—Oxime Rearrangement.
Authors: Guven Sinem , Ozer Merve Sinem , Kaya Serdal , Menges Nurettin , Balci Metin 
Published: September 2015

AbstractThe synthesis of pyrrole and indole derived oximes and their Au(III)‐catalyzed reactions are described.
ChemInform Abstract: Selective Access to 3‐Cyano‐1H‐indoles, 9H‐Pyrimido[4,5‐b]indoles, or 9H‐Pyrido[2,3‐b]indoles Through Copper‐Catalyzed One‐Pot Multicomponent Cascade Reactions.
Authors: Li Bin , Guo Shenghai , Zhang Ju , Zhang Xinying , Fan Xuesen 
Published: September 2015

AbstractThe direction of the reaction of tribromides (I) with aryl aldehydes depends on the amount of the aldehydes and ammonia to afford 3‐cyano‐1H‐indoles (III) or 9H‐pyrimido[4,5‐b]indoles (IV).
ChemInform Abstract: Catalytic ortho‐Acetoxylation of Masked Benzyl Alcohols via an Exo‐Directing Mode.
Authors: Ren Zhi , Schulz Jonathan E. , Dong Guangbin 
Published: September 2015

Abstract2,6‐Dimethoxybenzaldoxime is found to be a highly efficient directing group for the ortho‐acetoxylation of various masked primary and secondary benzyl alcohols.
ChemInform Abstract: Site‐Selective Approach to β‐Fluorination: Photocatalyzed Ring Opening of Cyclopropanols.
Authors: Bloom Steven , Bume Desta Doro , Pitts Cody Ross , Lectka Thomas 
Published: September 2015

AbstractA selective photo‐promoted ring‐opening/β‐fluorination process of cyclopropanols is developed to afford diverse β‐fluorinated ketones.
ChemInform Abstract: New Convenient Five‐Component One‐Pot Synthesis of 3‐Alkyl‐6‐amino‐1,4‐dihydro‐4‐{ [(1,2,3‐triazol‐4‐yl)methoxy]phenyl}pyrano [2,3‐c]pyrazole‐5‐carbonitrile Derivatives.
Authors: Dabiri Minoo , Salehi Peyman , Fakharian Mahsa , Kazemi Movahed Siyavash , MaGee David I. 
Published: September 2015

AbstractTitle compounds [(V) and (VII)] are synthesized through a very simple, highly efficient and environmentally benign one‐pot five‐component reaction in good to high yields.
ChemInform Abstract: Stereoselective Preparation of (E)‐ and (Z)‐Di‐ and Trisubstituted 1,3‐Butadienes.
Authors: Takeda Takeshi , Tateishi Keiichiro , Tsubouchi Akira 
Published: September 2015

AbstractBoth (E)‐ and (Z)‐1,1‐disubstituted as well as 1,1,2‐trisubstituted 1,3‐butadienes are stereoselectively obtained from anti‐β‐hydroxysilanes by Peterson elimination under acidic or basic reaction conditions, respectively.
ChemInform Abstract: Metal‐Free N‐Arylation of Secondary Amides at Room Temperature.
Authors: Tinnis Fredrik , Stridfeldt Elin , Lundberg Helena , Adolfsson Hans , Olofsson Berit 
Published: September 2015

AbstractVarious tertiary acyclic amides are regiospecifically obtained utilizing the high reactivity of diaryliodinium salts.
ChemInform Abstract: Dibromofluoromethylation of Aryl Grignard Reagents with Dibromodifluoromethane in the Presence of LiBr.
Authors: Shiosaki Masahiro , Inoue Munenori 
Published: September 2015

AbstractAryl Grignard reagents generated from electron withdrawing aryl iodides and bromides react with dibromodifluoromethane to give dibromofluoromethylarenes.
ChemInform Abstract: Metal‐Free Efficient Cross Coupling of Aromatic Aldehydes with Aryldiazonium Tetrafluoroborates Using DTBP as a Radical Initiator.
Authors: Tripathi Shubhangi , Singh Sachchida N. , Yadav Lal Dhar S. 
Published: September 2015

AbstractThe presented method represents the first example for the preparation of diarylketones via radical‐radical cross coupling.
ChemInform Abstract: Catalytic Amidation of Unactivated Ester Derivatives Mediated by Trifluoroethanol.
Authors: Caldwell Nicola , Jamieson Craig , Simpson Iain , Watson Allan J. B. 
Published: September 2015

AbstractA novel and versatile organocatalytic amidation method facilitated by inexpensive 2,2,2‐trifluoroethanol is presented.
ChemInform Abstract: Expedient Strategy for the Synthesis of 5‐Acylethynylpyrrole‐2‐carbaldehydes
Authors: Tomilin Denis N. , Sobenina Lyubov N. , Markova Marina V. , Gotsko Maxim D. , Ushakov Igor A. , Smirnov Vladimir I. , Vaschenko Alexander V. , Mikhaleva Albina I. , Trofimov Boris A. 
Published: September 2015

Abstractusing acetal protection of the aldehyde functionality
ChemInform Abstract: Organocatalytic Highly Enantioselective Substitution of 3‐(1‐Tosylalkyl)indoles with Oxindoles Enables the First Total Synthesis of (+)‐Trigolutes B.
Authors: Huang Jian‐Zhou , Zhang Chen‐Long , Zhu Yi‐Fan , Li Lu‐Lu , Chen Dian‐Feng , Han Zhi‐Yong , Gong Liu‐Zhu 
Published: September 2015

AbstractThe base promoted coupling of functionalized oxindoles (I) and (V) with 3‐(1‐tosylalkyl)indoles in the presence of bifunctional thiourea catalyst is developed.
ChemInform Abstract: Synthesis of Functionalized 2‐Isoxazolines as Three‐Dimensional Fragments for Fragment‐Based Drug Discovery.
Authors: Tran Ngoc Chau , Dhondt Heleen , Flipo Marion , Deprez Benoit , Willand Nicolas 
Published: September 2015

AbstractIn situ generated nitrile oxides undergo 1,3‐dipolar cycloaddition with alkenes to give 2‐isoxazoline derivatives.
ChemInform Abstract: Photocatalytic Oxidative Heterocyclization of Semicarbazones: An Efficient Approach for the Synthesis of 1,3,4‐Oxadiazoles.
Authors: Kapoorr Ritu , Singh Sachchida N. , Tripathi Shubhangi , Yadav Lal Dhar S. 
Published: September 2015

AbstractAn efficient and metal‐free method for the one‐pot synthesis of various 5‐substituted 2‐amino‐1,3,4‐oxadiazoles (II) utilizing visible light and atmospheric oxygen under mild reaction conditions is developed.
ChemInform Abstract: Organocatalyzed Oxidative N‐Annulation for Diverse and Polyfunctionalized Pyridines.
Authors: Khanal Hari Datta , Lee Yong Rok 
Published: September 2015

AbstractA novel strategy for the organocatalyzed synthesis of functionalized pyridines via a three‐component, one‐pot‐reaction of ketones, α, β‐unsaturated aldehydes, and ammonium acetate is developed.
ChemInform Abstract: Expedient Copper‐Free One‐Pot Alkynylation—Cyclization Sequence for the Preparation of 2‐Substituted 7‐Azaindoles.
Authors: Lessing Timo , Sterzenbach Fabian , Mueller Thomas J. J. 
Published: September 2015

AbstractThe title azaindoles (III), (V), (VII) are rapidly and efficiently synthesized from 2‐aminopyridyl halides and terminal alkynes without any activation or protection of the amino nitrogen of the 2‐aminopyridyl halides.
ChemInform Abstract: Synthesis of Imidazo[4,5‐e]thiazolo[2,3‐c]‐1,2,4‐triazine‐2,8‐diones via a Rearrangement of Imidazo[4,5‐e]thiazolo[3,2‐b]‐1,2,4‐triazine‐2,7‐diones in the Reaction with Isatins.
Authors: Gazieva Galina A. , Izmest'ev Alexei N. , Nelyubina Yulia V. , Kolotyrkina Natalya G. , Zanin Igor E. , Kravchenko Angelina N. 
Published: September 2015

AbstractDepending only on stoichiometry of base and refluxing time either thiazolo[3,2‐b]‐ or thiazolo[2,3‐c]‐1,2,4‐triazines (III) or (IV), resp., are accessible.
ChemInform Abstract: Organoborane Catalyzed Regioselective 1,4‐Hydroboration of Pyridines.
Authors: Fan Xiaoting , Zheng Junhao , Li Zhen Hua , Wang Huadong 
Published: September 2015

AbstractThe hydroboration of pyridines, catalyzed by a bulky organoborane, proceeds under metal‐free conditions and shows excellent chemo‐ and regioselectivity.
ChemInform Abstract: Inverse Regioselectivity in the Silylstannylation of Alkynes and Allenes: Copper‐Catalyzed Three‐Component Coupling with a Silylborane and a Tin Alkoxide.
Authors: Yoshida H. , Hayashi Y. , Ito Y. , Takaki K. 
Published: September 2015

AbstractReversed regioselectivity, compared to conventional silylstannylation reactions under Pd‐catalysis, is achieved using silyl boranes (II) and tin alkoxides (III) and (VII) in a one‐pot reaction to generate either 2‐silyl‐1‐stannyl‐1‐alkenes (IV)/(V) from alkynes (I) and 1‐silyl‐2‐stannyl‐2‐alkenes (VIII)/(IX) from allenes (VI).
ChemInform Abstract: 24,25‐Dihydrolimocinol, a new Triterpenoid from Fresh Fruits of Melia azadirachta
Authors: Misra Laxminarain , Gupta Sonika , Sangwan Rajender S. 
Published: September 2015

Abstractisolation and structure elucidation of 24,25‐dihydrolimocinol (I)
ChemInform Abstract: Synthesis by Microwave‐Assisted 1,3‐Dipolar Cycloaddition of 1,2,3‐Triazole 1′‐Homo‐3′‐isoazanucleosides and Evaluation of Their Anticancer Activity.
Authors: Ferreira da Costa Joana , Garcia‐Mera Xerardo , Caamano Olga , Brea Jose Manuel , Loza Maria Isabel 
Published: September 2015

AbstractRacemic isoazanucleosides (III) are synthesized by microwave‐assisted 1,3‐dipolar cycloaddition of proline derivative (I) with various alkynes.
Les effets du gel d'une caisse de retraite sur la performance et le risque des entreprises
Authors: Champagne Claudia , Chrétien Stéphane , Coggins Frank 
Published: September 2015

AbstractThis study considers the effect of freezing defined benefit pension funds on shareholder risk and returns. The conditional models used in this study directly assess the effects of a pension fund freeze on returns and on systematic and residual risk. While pension fund freezes do not significantly affect performance or systematic risk, they do significantly reduce short‐term residual risk. Pension fund freezes therefore do not generally present significant financial advantages to shareholders. Only shareholders of funds in crisis would benefit from significant systematic risk reductions. Copyright © 2015 ASAC. Published by John Wiley & Sons, Ltd.