bluuebunny/crossref_metadata_2025_split huggingface dataset:
PET/CT with <sup>18</sup>F-PSMA-1007 in Diagnostics of Primary and Recurrent Lesions of Clear-cell Renal Cell Carcinoma in Comparison with <sup>18</sup>F-FDG: Prospective Study
Authors: Ilyakov V. S. , Pronin A. I. , Parnas A. V. , Subbotin A. S. , Krylov A. S. , Geliashvili T. M. , Bezumova E. V. , Mehedova O. V. , Nesterova N. I. , Matveev V. B. 
Published: July 2024

Introduction: Attempts have been made to use various RPs, other than 18F-FDG in the diagnostics of renal cell carcinoma (RCC), with promising results demonstrated by PSMA-specific RPs, in particular 18F-PSMA-1007.A prospective study was conducted at N.N. Blokhin NMRCO to establish capabilities of PET/CT with 18F-FDG and 18F-PSMA-1007 in primary and recurrent ccRCC diagnostics.Material and methods: Forty-eight patients were included in the study, 28 with renal masses and 20 with suspected local recurrence of ccRCC. Biopsy results were available in all patients. All patients underwent PET/CT with 18F-PSMA-1007 and 18F-FDG.Results: Thirty-nine renal neoplasms were identified in 28 patients. 24 of 39 foci (21 patients) were PSMA-positive and 18 of 39 foci (16 patients) were FDG-positive. No false-positive foci were identified. The sensitivity, specificity, positive and negative predictive value in primary RCC were: for 18F-PSMA-1007 — 75, 100, 100 and 85 %, respectively; for 18FDG — 57, 100, 100 and 76 %, respectively. The SUVmax level of 18F-PSMA-1007 exceeded 18FDG in 27 of 28 patients (38 foci); the tumor/background ratio was higher in 16 of 28 patients (24 foci). Tumor thrombosis was detected in 6 patients (PSMA-positive 6 of 6, FDG-positive 5 of 6). PSMA-SUVmax levels in thrombi exceeded 18FDG in all patients, tumor/background ratio in 5 out of 6 patients. Local recurrence was detected in 13 of 20 patients (27 foci). 10 foci in the remaining 7 patients were considered as false positives. No false-negative results were obtained. Sensitivity, specificity, positive and negative predictive value in the diagnosis of local recurrence of ccPCC: 18F-PSMA-1007 — 100, 94, 81 and 100 %, respectively; 18FDG -100, 89, 68 and 100 %, respectively.SUVmax and tumor/background ratio were found to correlate with primary tumor and recurrent node sizes for both RPs.Discussion and conclusions: At the moment, the role of 18F-PSMA-1007 in RCC diagnostics has not been defined. We can note the high efficiency of this RP in the assessment of the primary focus and recurrence of ccRCC, its usage is justified in cases, when routine diagnostic methods do not give an unambiguous answer.The possibilities of 18F-PSMA-1007 in metastatic ccRCC diagnostics are of the greatest interest. A significant prospective material has been collected in our department, which will be the basis for further study of this RP in the diagnostics of metastatic ccRCC.
ARTIKEL REVIEW: GELOMBANG ELECTROMAGNETIC EXTREMELY LOW FREQUENCY (ELF) DAN TINGKAT STRESS MANUSIA
Authors: Galuh Rosida Anisa Suci , Sudarti Sudarti , Yushardi Yushardi 
Published: July 2024

Tujuan adanya penelitian dengan review artikel ini adalah untuk mengetahui adanya pengaruh EM ELF terhadap stress, apakah dapat berdampak baik seperti digunakan sebagai terapi ataukah berdampak buruk seperti meningkatkan stress. Electromagnetic dengan frekuensi sangat rendah (Extremely Low Frequencytau ELF) merujuk pada gelombang elektromagnetik dengan frekuensi yang sangat rendah, biasanya dalam rentang beberapa hertz (Hz) hingga beberapa kilohertz (kHz). Gelombang ini memiliki panjang gelombang yang sangat panjang, yang berarti bahwa satu gelombang dapat memiliki panjang yang sangat besar, hingga ratusan hingga ribuan kilometer. Artikel review ini menggunakan metode deskriptif research berbasis artikel review. Dalam penelitian ini didapatkan hasil bahwa Electromagnetic Extremely Low Frequency dapat menyebabkan stress dan juga dapat digunakan sebagai terapi stress secara bersamaan. Namun, kesimpulannya EM ELF dapat digunakan sebagai terapi apabila frekuensi gelombang yang diberikan pas dan sesuai dosis yang dianjurkan dan dapat menyebabkan stress apabila dilakukan dengan gelombang yang amat tinggi serrta intesitas pemaparan yang juga berpengaruh dalam dampak EM ELF sebagai pemicu stress dan terapi stress ini.
Effect of Antenatal Corticosteroid on Cardiotocographic Parameters in Pregnant Women
Authors: Nazia Ishrat  , Shahina Perween  , Gul Ar Navi Khan  
Published: July 2024

Objective: To evaluate the effect of dexamethasone administration on cardiotocographic parameters.
Material & Methods: A prospective cohort study was carried out in the department of Obstetrics and Gynaecology in collaboration with Department of physiology, Jawaharlal Nehru Medical College & Hospital. Total 100 pregnant women between gestational age of 28 weeks to 38 weeks were enrolled in the study. They underwent cardiotocography on day 0 i.e. before administration of injection dexamethasone, on day 2 (after 48 hours of first dose) and on day 4-7. Patients received injection dexamethasone 6 mg i.m. 4 doses at an interval of 12 hours for various indications like preterm labor (PTL), preterm prelabor rupture of membrane (PPROM), placenta previa and previous CS. Outcome measures were changes in Baseline FHR(Fetal Heart Rate), Baseline variability, Acceleration and DFMC before and after dexamethasone administration.
Results: All parameters including Baseline FHR, Accelerations, baseline variability and daily fetal movement counts were significantly reduced on day 2 of injection dexamethasone administration and returned to baseline values after 4 to 7 days of receiving dexamethasone.
Conclusions: Dexamethasone administration resulted in transient reduction in baseline FHR, acceleration, variability and DFMC that mimic fetal compromise, hence clinicians should be aware of this phenomena to avoid iatrogenic preterm delivery of the fetus.
A Study on Socio-Demographic Profile, Knowledge and Practice of Dog Bite Patients Registered at Rural Field Practice Area-Gims, Kalaburagi, Karnataka: A Cross Sectional Study
Authors: Manjunatha V K  , G. Ajay Kumar  , Meenakshi M Dhadave  
Published: July 2024

INTRODUCTION: Rabies is known as acute, highly fatal, hydrophobic viral disease of CNS system. Majority (99%) spread by Dog bite which is major public health problem in rural than urban area. In India17.4 million cases and 24,000 deaths occur every year, each second there is one dog bite. It is 100% preventable disease if all efforts must be made by the health system to prevent even a single case of rabies, by make plans and policies for its prevention under rabies control program. To look into socio-demographic profile, knowledge and practice among dog bite patients registered at PHC-Hiresavalagi, Hence the current study was taken.
OBJECTIVES:

To find the socio-demographic profile of dog bite patients.
To assess the Knowledge and Practice of dog bite wound management among dog bite patients.

METHODOLOGY: A cross sectional study was conducted among alldog bite patients at rural health training centre, Hiresavalagi for period of 7 months by census sampling method. The data was collected by using a predesigned and pretested questionnaire A contact number was obtained from dog bite register, we conducted interview through telephone and who are not respondents to telephone we were approached directly.the data was entered into Microsoft Excel sheet and will be analysed using software SPSS version 16.0.
RESULTS & CONCLUSION: Our study found that 106(93.8%),7(6.2%) was inadequate & adequate knowledge and 82(72.6%),31(27.4%) was inadequate& adequate practice respectively. Majority 76(67.2%) Patients completed course oftreatment,36(31.9%) was lost to treatment and follow up due to work load, out of station and 1(0.9%) developed new symptoms during the course of treatment. Various control and preventive measures are taken under rabies control program along with health education and promotion, among population by using mass medias, advertisements, role plays & skits at community level. To complete course of treatment strict guidelines should follow at all Health training centre, hospitals & peoples.
An Observational Study on Changes in Psychological Parameters in Covid 19 Recovered Patients
Authors: Dasgupta G  , Roy P  , Acharya R.P  , Malik. C  , Talukdar. A  
Published: July 2024

The rapid escalation of COVID-19 pandemic resulted in a World Health Organization (WHO)-declaring public health emergency of international concern. The present study aimed to measure the prevalence of depression, anxiety, stress, post-traumatic stress disorder and cognitive impairment among the covid19 recovered patients. This observational study included patients with a history of COVID-19 who were admitted in the IPD of Medical College & Hospital, Kolkata. Data was collected from the patients after 14 days from recovering from COVID Patients were assessed through three questionnaire, Depression, Anxiety and Stress Scale - 21 (DASS-21), PTSD Checklist PCL-5 and Montreal Cognitive Assessment (MOCA). Statistical analysis showed significant differences between Anxiety and PTSD score of male and female patients. Significant difference was found in the depression, anxiety and PTSD score, when comparison was made on the basis severity level of Covid. Significant difference was found in the depression, stress and MOCA score, when comparison was made on the basis of educational status of patients. Duration of hospital stay and oxygen therapy were positively associated with anxiety, depression, stress and score while MOCA scores were found to be negatively associated. The result of the present study showed that no significant difference in the psychological variables was observed when comparison was made in terms of comorbidity. In conclusion, we should pay special attention to the mental health status of female patients, severe type individuals as we provide treatments to the COVID-19 patients.
Reproductive Tract Infections: Prevalence and Associated Socio Demographic Factors among Married Women in Rural Areas of Aligarh
Authors: Saira Mehnaz  , Shivangi kumari  , Ali Jafar Abedi  , M. Athar Ansari  
Published: July 2024

Background: Reproductive Tract Infection (RTI) is a broad term that includes Sexually Transmitted Infections(STI). This is a major public health problem worldwide, affecting the quality of life and causing serious morbidity and mortality. They have a direct impact on reproductive and child health through infertility, cancers, and pregnancy complications, and they have an indirect impact through their role in facilitating the sexual transmission of the human immunodeficiency virus.
Objectives: To find the prevalence and determinants of RTI/STI among married women of reproductive age group in rural areas of Aligarh.
Methods: A community-based cross-sectional study was conducted in the peri-urban and rural field practice areas of the UrbanHealth Training Center(UHTC), and Rural Health Training Centre(RHTC), J N Medical College, Aligarh, for a period of 1 year. The data were collected by using a pretested, semi-structured with both open and closed-ended questionnaire from 500 married women of reproductive age group. Married females who had given consent and residing for more than 6 months in the field areas were included in the study. Those females having any chronic illness and not given consent were not included in the study.
Statistical analysis used: Frequency, proportion and chi square test applied using 20.0 software.
Results: Prevalence of RTI/STI symptoms was found to (42.8%) in rural areas.RTI symptoms were found in study subjects having lower educational status, who were not using any contraceptive method, not following good menstrual hygiene, early marriage age had husband history of RTI/STI, had a history of abortion, had a history of violence, and increased parity.
Conclusions: Prevalence of symptoms found to be associated with these females having low educational status, early age of marriage, high parity, partner history of reproductive Tract Infections, history of violence etc.
Verstärkung ermüdungsgeschädigter Stahlbauteile mittels geschweißter eisenbasierter Formgedächtnislegierungen/Reinforcement of fatigue damaged steel components with welded iron-based shape memory alloys
Authors: Li Zheng , Herzog Bastian , Erlemann Raphael , Geißler Karsten 
Published: July 2024

Die grundsätzliche Eignung geschweißter eisenbasierter Formgedächtnislegierungen (Fe-SMA) zur Verlängerung der Restnutzungsdauer von Stahlbauteilen mit Ermüdungsrissen wurde in ersten experimentellen Untersuchungen analysiert. Dazu wurden kompakte Zugproben (CT) aus einem 12 mm dicken Stahlblech gemäß ASTM-E647 hergestellt und zunächst zur Erzeugung eines 40 mm langen Risses zyklisch belastet. Anschließend wurden Streifen aus einer Fe-SMA beidseitig über den Risspositionen aufgeschweißt. Beim Schweißen an bereits geschädigten Bauteilen ist besondere Vorsicht und sorgfältige Planung geboten. Trotz des kontraintuitiven Einbringens von weiteren Schweißkerben in ein bereits ermüdungsgeschädigtes Bauteil wurden diese ersten Untersuchungen aus zwei Hauptgründen angestrebt. Zunächst sollten für neuartige Ertüchtigungsmaßnahmen alle denkbaren Verbindungsmethoden untersucht werden also neben dem Kleben und einer mechanischen Verankerung auch das Schweißen. Daneben sollte experimentell untersucht werden, dass unter den erwartbaren Versagensmodi Nahtwurzel, Nahtübergang zum Fe-SMA und Nahtübergang zum Grundmaterial nicht letzterer maßgebend wird.

Der Artikel soll einen Beitrag zum theoretischen Verständnis von Fe-SMA liefern und die grundsätzliche Eignung der Verbindung der Fe-SMA mittels Schweiße bei begrenzter Restnutzungsdauer untersuchen. Ein Teil der Proben wurde zur Aktivierung der Fe-SMA erhitzt, um eine Vorspannung zu erzeugen. Die Proben wurden erneut einer zyklischen Belastung mit konstanter Amplitude ausgesetzt, während der das Risswachstum überwacht wurde. Spannungskonzentrationen am Riss konnten wirksam reduziert werden, wodurch an den untersuchten CT-Proben eine verlängerte Restlebensdauer erreicht werden konnte. Die Versagensmodi der experimentellen Untersuchungen bestätigen, dass bei entsprechender Konstruktion und Dimensionierung keine weitere maßgebende Kerbe in direkter Umgebung des ursprünglichen Schadens in das bereits geschädigte Ausgangsbauteil eingebracht wird. Die grundsätzliche Eignung der bewährten Verbindungstechnik Schweißen für derartige Verstärkungsmaßnahmen konnte gezeigt werden. Künftig sind die nicht abschließend untersuchten Fragen hinsichtlich Optimierung der Schweißnahtgeometrie, Dimensionierung und Form der Fe-SMA mit zugehöriger Aktivierungstemperatur weiter zu untersuchen. Daneben sind vor allem die sich ergebenden Fragen für die Anwendung, zum Beispiel bezüglich Dichtheit und Reduzierung des Kerbfalls des Ausgangsbauwerk, vor dem Hintergrund der begrenzten Restnutzungsdauer des bereits geschädigten Bauteils zu untersuchen und entsprechende Empfehlungen zu erarbeiten.
ХОЗЯЙСТВЕННО-БИОЛОГИЧЕСКАЯ ОЦЕНКА СОРТОВ ГОЛУБИКИ ВЫСОКОРОСЛОЙ В УСЛОВИЯХ АЛМАТИНСКОЙ ОБЛАСТИ
Authors: Кампитова Гульфаридат , Кухарчик Наталья , Атабай Айбек , Туткабек Акбота , Оразахмет Ардак 
Published: July 2024

Голубика высокорослая занимает достойное место среди нетрадиционных ягодных культур, которая одновременно может использоваться в пищевых и лекарственных целях. Благодаря уникальному сочетанию вкусовых и лечебно-профилактических качеств плодов, она получает все большее распространение в приусадебных участках и производственном садоводстве Казахстана. В статье приведены результаты хозяйственно-биологической оценки 7 сортов голубики высокой в условиях нижнегорной зоны Алматинской области. Изучены общее состояние, зимостойкость, пораженность болезням, параметры развития вегетативной части растения, способность формировать первый урожай в трехлетнем возрасте, качественные показатели ягод. Выделенные сорта представляют практическую ценность для садоводства Казахстана. Все исследуемые сорта голубики высокой по своим хозяйственно-биологическим особенностям имеют существенную перспективу возделывания их в условиях Алматинской области, сформировали качественные плоды, что свидетельствует об успешной реализации их адаптационного потенциала в этих условиях. Наилучшие показатели адаптивности показал сорт Duke. Растения голубики соответствуют сезонным ритмам развития, формируют урожай и укладываются в период вегетации в изучаемых условиях. Зимостойкость и высокие вкусовые качества являются основными достоинствами при возделывании их в Казахстане.
ДЕГРАДАЦИЯЛАНУ МЕН ШӨЛЕЙІТТЕНУДЕН ҚОРҒАУ ҮШІН ФЕРМЕНТТІК ИНДУКЦИЯЛАНҒАН КАЛЬЦИЙ КАРБОНАТЫНЫҢ ТҰНБАСЫ АРҚЫЛЫ ҚҰМ МЕН ТОЗҒАН ТОПЫРАҚТЫ НЫҒАЙТУ
Authors: Даулеткұл Мейіржан , Тұнғышбаева Зина , Янкьевич Урсулла , Қыдырбава Әсем , Турсынханқызы Майра 
Published: July 2024

Бұл мақалада ферменттік индукцияланған кальций карбонатының тұнбасы әдісі яғни, EICP (Enzymatic Induced Calcite precipitation) - ерітіндісінің тозған топырақтың құрылымын нығайту. Ауыл шаруашылығында шөлейітті зонадағы құмды нығайту үшін пайдаланылды.Құмды дауылдар - әлемдегі ауыр табиғи апаттарға жатады және онымен күресудің тиімді және экологиялық таза әдісін ұсынудың маңызы зор. Бұл биогеотехникалық әдіс-несепнәрдің гидролизденіп, уреаза ферментімен катализдену нәтижесінде кальций карбонатытұнбасының (CaCO3) түзілуі арқылы жасалынады. Ерітіндінің құрамы 1М несепнәрден, кальций хлоридінен0,78M(CaCl2) және 4г/л уреаза ферментінен тұрады.Осы аталған ерітіндімен өңдеу нәтижесінде құмның бөлімдерін бір-бірімен байланыстыратын, кристалл түзеді, яғни карбонаттың тұндырылуы барысында, топырақтың өткізгіштігін төмендете отырып, оның беріктік қасиетін қамтамасыз етеді. Алайда, бұл әдістің негізіндежасалған ерітіндінің жасауға қолданылатын уреаза ферментінің көп мөлшерде қажеттілігіне байланысты, ауқымды қаржыны талап етеді. Тек ферменттің өзі ерітінді дайындауға кететін шығынның 95%-дан астамын құрайды. Сондықтан, зерттеу жұмыстарын ары қарай жетілдіру үшін уреаза ферментін алмастыратын яғни, уреаза ферментін түзетін табиғи субстракт қажет.Шөптесін өсімдіктердің тұқымын және ферменттік өңдеу әдістері экологиялық үйлесімділігі болуы шөлейттенуді азайтуға тиімділігін көрсетті.Өңдеу нәтижесінде жел эрозиясы мен жауын-шашынға да төзімділігі айтарлықтай дәрежеде жақсартқанын көрсетті, бұл шөлейттенудің алдын алудың тиімді әдісін қамтамасыз етеді.
Бұл зерттеу жұмысына уреаза ферментін ауыстыратын табиғи шикізат өнімі ретінде фермент майбұршақ – Соя-Glycine max (L.) Merrill бөлініп алынды.Топырақты(Ақтау құмы) EICP ерітіндісімен өңдеу арқылы, олардың құрамындағы ферменттердің белсенділігін арттырып, карбонаттың тұндырылу дәрежесінің жоғары болуына алып келеді. Сонымен қатар, топырақты ферменттік индукцияланған кальций карбонатының ерітіндісімен өңдеу барысында түзілген ағын сулардан несепнәр мен кальций хлоридін түзіледі, бірақ уреазалық ферменттерді түзбейтіндігі анықталды. Фермент топырақ құрамындағы несепнәр мен кальций карбонатымен әрекеттесіп, карбонаттың тұндырылуын түзіп, топырақ бөлімдерінің бір-бірімен байланыстыру арқылы кальций карбонатының кристаллын түзеді. Түзілген кальций карбонатының кристаллы топырақ бөлімдерін нығайтып, оны борпылдақ күйінен қатты тығыздалған күйге айналдырады.
Нығайтылған құм бағандары сканерлеуші электронды микроскоппен түсірілді.
ГЕОДЕЗИЯДА ҚОЛДАНЫЛАТЫН АУДАН АНЫҚТАУ ӘДІСТЕРДІҢ ДӘЛДІКТЕРІН ЗЕРТТЕУ
Authors: Пентаева Салтанат , Сулейменова Диана , Пентаев Толеубек , Жилдикбаева Айжан , Баухан Аблайхан , Гурскиене Виргиния 
Published: July 2024

Мақалада жер беті учаскелерінің шаруашылық міндетіне, қызметіне, пішініне, орналасу жағдайларына және пландық-картографиялық материалдарына байланысты жалпы және жеке бөліктерінің аудандарын анықтау әдістері мен өлшеу дәлдіктері келтірілген. Бұл әдістердің қайсысы болсада қолдану барысында қателіксіз болмайды. Сол қателіктер алынатын нәтижелер мен мәндеріне көп әсер етуіне байланысты зерттеулерді қажет етеді. Көптеген инженерлік есептеулерді шешу үшін карта мен планда аудандарды анықтауда графикалық, аналитикалық және механикалық әдістерді қолданады. Аудандарды анықтау барысында өлшеу элементтері мен олардың өлшену дәлдіктері әртүрлі болады. Сондықтан аудан анықтау кезіндегі қолданылатын әдістер бойынша жіберілетін қателіктер сарапталып, олардың әсерлерін азайту және болдырмау жолдары зерттелген. Жер пайдаланудың мөлшері шаруашылықтың өндірістік қуатына және мамандығына байланысты анықталады. Жобаланған мөлшері тиімді болу керек.
Жоғарыда айтылғандай, жер иеленушіліктің және жер пайдаланудың ауданы мен құрамы шаруашылықтың өндірісіне, мамандығына тікелей байланысты. Мысалы, соңғыларға сай олардың талаптарын қанағаттандыратын жер пайдаланудың ауданын табу. Басқаша айтқанда, ол рационалды (ұтымды) болуға тиісті – оған орналастырған ауылшаруашылық мекемесі (серіктестік немесе басқа агроқұрылым) басқаруға ыңғайлы (apa қашықты өтуге өте көп шығын шығармай), шаруашылықтың барлық салаларының табысты дамуына алқаптардың қажетті аудандары мен қатынастарын қамтамасыз ету.
Financial Performance Analysis of Dumai City Regional Government Financial Reports
Authors: Yuandina Yuandina 
Published: July 2024

This research is intended to determine the financial performance of the Dumai City Region using analytical techniques in the form of comparative techniques, common size techniques and ratio techniques. The ratio technique uses descriptive formulas including: PAD Effectiveness Ratio, Regional Financial Efficiency Ratio, Harmony Ratio, Spending Pattern Indicator Ratio, Regional Financial Independence Ratio, Solvency Ratio, and Liquidity Ratio. This research is quantitative descriptive in nature by calculating financial data obtained from the Dumai City Regional Government Financial Report for the 2022 fiscal year. The results of research using comparative techniques show that the financial performance of Dumai City in 2022 is quite optimal, at with a percentage of realized income that exceeds the target of 102 .53% and actual expenditure reached 93.55% of the budgeted target. Meanwhile, financial performance using the Common Size Technique shows that the largest income from total Regional Revenue comes from the General Allocation Fund (DAU). Financial Performance on the PAD Effectiveness Ratio indicator is classified as effective, at 102.53%, the Regional Financial Efficiency Ratio (REKD) is inefficient, at 109.99%, the Harmony Ratio is included in the standard category, at 17.27% for capital expenditure, Indicator Ratio Shopping patterns are classified as less efficient, at 43.09%, the Regional Independence Ratio is included in the participatory criteria, at 51.20%, the Solvency Ratio is considered very effective, at 3.83%, and the Liquidity Ratio is classified as very effective, at 2.5–5.61%.