bluuebunny/crossref_metadata_2025_split huggingface dataset:
P-117 ASSESSING EXHALED BREATH CONDENSATE AS MINIMALLY INVASIVE MATRIX FOR LUNG-RELATED BIOMARKER ANALYSES
Authors: De Ryck Evi , Verscheure Eline , Schlünssen Vivi , Stierum Rob H , Pronk Anjoeka , Godderis Lode , Ghosh Manosij 
Published: July 2024

Abstract

Introduction
Inhalation is an important route wherethrough occupational exposure can reach and potentially affect pulmonary function. Recently, there is a shift towards using less invasive matrices. We investigated quality and stability of exhaled breath condensate (EBC) as a minimally invasive matrix to identify lung-related biomarkers.

Methods
EBC and lung function measurements were collected, from twelve healthy participants twice six months apart (T1,T2) using Medivac® TurboDECCS System and spirometry. Cytokines, MMP-1, 2, 7, and 9, VEGF/Flt1, E- and P-selectin, α-amylase activity, proteomics, CysLTs, LTB4, and TXB2 were measured in EBC. This study was approved by the Ethics Committee Research UZ/KU Leuven (S64599).

Results
Only two out of twenty-four EBC samples exhibited detectable α-amylase activity. Proteomics showed presence of proteins involved in several biological processes, originating from different cellular components, with different molecular functions. Negative associations were shown between forced expiratory flow (FEF) 25% and TXB2(T2), and FEF 75% and forced expiratory volume within the first second (FEV1) and IFNγ(T1). Peak expiratory flow positively associated with CysLTs(T1) and IL6(T2), FEF 25% with CysLTs(T1), FEF 75% with IL8(T1), FEV1 with IL2 and IL6(T2), and forced vital capacity with IL1β, IL2, and IL6(T2).

Discussion
With only limited saliva contamination, the collection procedure for EBC is robust. Several associations were shown between spirometry parameters and various markers, suggesting the potential of EBC as alternative minimally invasive matrix.

Conclusion
So far, these results support the usage of EBC to identify biomarkers for lung function. EPHOR is funded by the European Union’s Horizon 2020 research and innovation programme under grant agreement number 874703.
P-121 POSITIVE OUTCOME EXPECTANCIES AND PERCEIVED RESILIENCE AS POTENTIAL SOURCES OF WITHIN-GROUP HETEROGENEITY IN THE REPORTING OF EXHAUSTION SYMPTOMS AMONG SWEDISH SCHOOL PRINCIPALS
Authors: Persson Roger , Leo Ulf , Håkansson Carita , Oudin Anna , Arvidsson Inger , Österberg Kai , Leo Ulf , Håkansson Carita , Oudin Anna , Arvidsson Inger 
Published: July 2024

Abstract

Introduction
Beliefs and expectations are psychological mechanisms of relevance for stress and health, yet they are often overlooked as a source of within-group heterogeneity when it comes to reporting epidemiological survey data. Accordingly, we examined to what extent positive outcome expectancies (POE) and perceived resilience change the reporting of exhaustion symptoms.

Methods
Cross-sectional data from 2219 Swedish school principals (78% women; mean age 49 years [SD 7 years]) were analyzed. The Karolinska Exhaustion Disorder Scale (KEDS) and the Lund University Checklist for Incipient Exhaustion (LUCIE) were used to classify exhausted versus non-exhausted principals. Low, medium, or high levels of POE and resilience were determined via generalized self-efficacy scores and two single items “Have you lately felt hopeful for the future” and “You are a stress tolerant person, that is, you quickly bounce back after difficulties in work and private life.”

Results
Most principals reported high Generalized self-efficacy (88.0%), high Hope for the future (67.6%), and high resilience (90.0%). Principals reporting low POE, or low resilience, reported more exhaustion symptoms. Adjusted logistic regression analyses showed that low Hope for the future scores were strongly associated with exhaustion in LUCIE (OR=12.3, 95% CI=8.0-19.0, p &lt;.001) and KEDS (OR=12.6, 95% CI=8.4-18.8, p&lt;.001).

Discussion
The associations between low hope for the future and exhaustion symptoms is a reminder that a positive outlook on life is a vital part of mental health and a potential area for psychological intervention.

Conclusion
Positive outcome expectancies and perceived resilience are potential sources of heterogeneity in the reporting of exhaustion symptoms in epidemiological surveys.
P-122 WORK-RELATED ROAD TRAFFIC ACCIDENTS: IMPACT OF THE EMERGENCE OF NEW PERSONAL MOBILITY DEVICES. ANALYSIS BASED ON DATA FROM A REGISTER OF ROAD TRAFFIC ACCIDENTS
Authors: Fort Emmanuel , Connesson Nicolas , Brière Julien , Ndiaye Amina , Gadegbeku Blandine , Charbotel Barbara 
Published: July 2024

Abstract

Introduction
In the last decade, in several countries, the use of personal mobility devices (PMDs) has steadily increased.

Objective
This study aimed to describe the characteristics of work-related road accidents and their evolution since the introduction of new PMDs in France, in terms of incidence and severity.

Methods
A cross-sectional study was performed using data from the Rhône Road Trauma Registry, focusing on users aged 18–70 years who were injured in work-related road accidents between 2015 and 2020.

Results
10,653 victims were identified. An increase in the number of work-related traffic injuries was observed, mainly due to an increase in the number of accidents while commuting (approximately 4%). The proportion of scooter drivers increased by more than 660%. In contrast, the share of car drivers decreased by 21% over the period, and motorized two-wheeler drivers by 24%. Most scooter users had upper limbs (59.2%), lower limbs (46.8%), face (21.2%) or head (17.9%) injuries. Most accidents were of low or moderate severity (97.9%; MAIS score &lt; 3) compared to other users (93.4% for pedestrians, 95.5% for motorized two-wheelers, 97.5% for bicycle, p&lt;0.0001). Less than one-fifth of injured PMD and scooter users wore helmets.

Discussion
The use of PMDs has steadily increased in France. However, accidents involving scooters or other PMDs seem to be of low severity.

Conclusion
Many head injuries could be prevented with more widespread use of helmets, among scooter- and other PMD users and bicycle users. Companies could take preventive actions to ensure that employees are better informed.
P-123 EVALUATION OF THE CAUSES OF DEATH OF PATIENTS WITH ESTABLISHED DIAGNOSIS OF ASBESTOSIS
Authors: Kovalevskiy Evgeny , Kashanskiy Sergey 
Published: July 2024

Abstract

Introduction
In assessing the prevalence of diseases potentially associated with asbestos exposure the mortality rates are recognized as the most reliable index. But this indicator does not allow to estimate the prevalence of asbestos-related diseases, which are often not indicated in death certificates as the main cause of death, such as asbestosis.

Methods
Initial review of the causes of death in a group of 850 chrysotile asbestos mining and enrichment workers with diagnosis “asbestosis” established in the territorial center of occupational health from 1946 to 2020 carried out using death certificates’ national electronic database.

Results
210 workers of the group died. The average age of deceased was over 60 years old. The peak age of mortality was for women 71-80 years, for men 61-70. Asbestosis was identified as the main cause of death for only 9 patients (3 men and 6 women). Most of the death causes (46.1%) were diseases of the circulatory system, malignant neoplasms (32.0%). In men, the main cancer sites were respiratory and chest organs (56.7%), digestive (20.0%), urinary tract (13.3%). Women died more often from cancer of the digestive organs (37.8 %), respiratory organs and chest (27.6%), female genital organs (13.8%) and breast (10.3%). The third ranking place was respiratory diseases (8.3%).

Discussion/Conclusion
Even initial review demonstrated that asbestosis itself in modern conditions is practically not considered as the main cause of death, which indicates the need for a wider study of the incidence of non-malignant occupational asbestos-related diseases in the country with special attention to exposure conditions, occupational history and lifestyle factors.
P-130 THE PREVALENCE OF STRESS AND BURN-OUT AMONG HEALTH CARE-PROFESIONNALS IN THE PREFECTURE OF MÉKNES CITY DURING COVID 19 PANDEMIC
Authors: Amellah Amal 
Published: July 2024

Abstract

Introduction
Psychiatric related diseases such as burnout and stress have recently begun to attract attention among health professionals espacialy during and in post pandemic period, our study aims to examine whether prevalence of burnout and stress are higher among community nurses and medical staff engaged in public health services of meknes city.

Methods
Our cross-sectional study involved 200 health workers in public hospitals working under stress during COVID 19 pandemic. A questionnaire was shared with participants during tow month. The degree of stress and burn out symptoms was assessed using the 14-item of perceived stress scale and the 23 items of the Maslach-burnout inventory.

Results and discussion
60% were women. A considerable proportion of participants reported higher score of percieved stress (47%) and 43% of respondants are calssed with a higher score of burn-out.
Multivariable logistic regression analysis showed that being married, and parent of children, and involved in intensive care units and in emergency services, were associated with a higher prevalence of stress and burnout. The Prevalence of burnout and stress are significantly elevated among nurses and medical stuff engaged during COVID19 pandemic

Conclusion
working in emergency services and during public health crisis appear to represent work environment factors contributing to stress and burnout.
P-132 THE PREVALENCE OF DECREASED KIDNEY FUNCTION IN MANUFACTURE WORKERS AND ITS ASSOCIATED RISK FACTORS: AN ANALYSIS OF BIG DATA FROM WEST JAVA, INDONESIA’S INDUSTRY WORKERS
Authors: Kekalih Aria , Nurhadi Ferdy , Ilyas Muhammad , Soemarko Dewi , Sugiarta Iwan 
Published: July 2024

Abstract

Introduction
Chronic kidney disease is a global health issue due to its increased prevalence, severe morbidity and mortality, and profound socio-economic effects. The manufacturing sector in Indonesia exposes many workers to long hours, heat, and low humidity, which may increase their risk of renal disease. Thus, early diagnosis of decreasing kidney function and related factors is essential.

Methods
A big data Analysis of 2304 manufacturing workers in West Java, Indonesia was performed using compiled 2022 medical checkup databases from twelve companies. West Java was chosen since it has the most workers in Indonesia. Gender, age, physical activity, history of urinary tract illnesses, smoking, alcohol, and current comorbidities (metabolic syndrome and urinalysis) are included. Manufacturing kinds, working hours, heat exposure, workload, prolonged seated &gt;4 hours, and ergonomic position were occupational factor risks. Kidney function was impaired when eGFR was below 90 mL/min/1.73 m². Univariate and multivariate risk factor analyses were performed.

Results
The prevalence of decreased kidney function was 33.8% of workers. The significant factor risks were male (aOR 2.52), age over 40 years old (aOR 2,48), conditions of grade I and II hypertension (aOR 1,88 and 2.15 consecutively), obesity (aOR 1.27) and working more than 20 years (aOR 1.93).

Discussion
Higher prevalence than average global prevalences indicated kidney failure threat. Recognising that heat exposure and ergonomic position were unrelated, workers’ drinking habits and implementation of hydration programmes must be monitored.

Conclusion
Imminent kidney failure must be prevented in manufacturing workers, especially in male, older, obese, and long-term manufacturing employees with hypertension.
P-133 ASSOCIATION BETWEEN WORKPLACE VIOLENCE AND ANXIETY AMONG HEALTHCARE WORKERS DURING THE COVID-19 PANDEMIC IN BRAZIL
Authors: Feijó Fernando , Reis Elaine , Helioterio Margarete , Werneck Guilherme , Araújo Tânia 
Published: July 2024

Abstract

Introduction
The COVID-19 pandemic changed several aspects of the work organization and aggravated psychosocial risk factors for healthcare workers. Those changes may be more serious in a social context where there is a lack of resources and huge social inequalities. Therefore, the aim of this study was to investigate the association between workplace violence/harassment and anxiety among healthcare workers in Brazil.

Methods
Cross-sectional study with a representative sample of public health employees who worked in the primary and secondary care in three municipalities in Bahia, northeastern Brazil, in 2021. Anxiety Disorder was measured by the Patient Health Questionnaire(PHQ). Workplace violence and bullying/harassment were assessed using the self-labeled method, with validated specific questions. A structured questionnaire and other validated instruments were used to assess sociodemographic, behavioral and psychosocial factors. Logistic regression was used to estimate prevalence odds ratios and 95% confidence intervals.

Results
1097 workers participated in the study. The prevalence of bullying was 8.2%, and the prevalence of Anxiety Disorder was 18.9%. After adjustment for confounders, healthcare workers exposed to verbal/physical aggression and workplace bullying had 1.90 (95% CI: 1.23-2.95) and 2.29 (95% CI: 1.41-1.37) higher odds of anxiety, compared to those non-exposed, respectively.

Discussion
The results highlight the possible role of the work organization for the occurrence of workplace aggression, workplace bullying and anxiety.

Conclusion
Interventions to prevent mental health outcomes, particularly anxiety, as well as sick leave and work disability, must focus on the work organization and managerial policies, minimizing psychosocial risk factors and eliminating violence and harassment from the healthcare environment.
P-143 SHIFTING THE FOCUS FROM EXPOSURE TO SOCIOECONOMIC STATUS IN OCCUPATIONAL EPIDEMIOLOGY: A PROTOCOL OF A CONCEPTUAL FRAMEWORK FOR A SOCIOECONOMIC RISK MATRIX
Authors: Hadidi Hamza , Hontoria Rodrigo , Salah Salah , Arshad Fatima , Uddin Ismihan A , Ashemi Qaseem , Maini Ishana , Moinuddin Ali 
Published: July 2024

Abstract

Introduction
Job exposure matrices (JEM) often neglect upstream socioeconomic variables and assume the exposure epidemiology lens. We propose a conceptual framework utilizing education, wealth, and healthcare access as primary indicators of occupational cardiorespiratory risk. This protocol encompasses key socioeconomic status (SES) predictors to produce a Socioeconomic Risk Matrix (SRM).

Methods
Prioritizing utilization in cohort studies, data will be obtained from the National Health and Nutrition Examination Survey. A random forest regression assigns each SRM variable a weighting according to its likelihood of impacting risk. Each variable contributes an ordinal risk level, where a 3-way matrix produces a 0 to 1 risk score. Relative risk of COPD will be estimated based on SRM risk quartiles using multinomial logistic regression.

Results
Using SRM as an interdisciplinary approach to occupational epidemiology identifies the magnitude of socioeconomic variables’ impact on occupational disease risk. We expect SRM to allow for expanded data utilization within and between occupational groups/clusters.

Discussion
This approach may indicate a necessity for analyzing additional SRM variables individually and inter-relatedly to support their associative impact on occupational, cardiorespiratory health outcomes. Remodelling SRM’s risk scoring structure may expose interactions between socioeconomic and lifestyle factors in the context of occupational exposure, providing a multidimensional approach to occupational risk estimation. The SRM lacks direct reproducibility, as different cohort samples reflect diverse SES combinations, however this orients future studies in occupational health to an SES-centric approach over traditional exposure-centric investigations.

Conclusion
SRM may act as a primer for improved SES matrices, incorporating variance in workplace and geo-cultural factors where relevant.
P-145 HOW MUCH DOES THE HOSPITAL WEIGHT? THE BODY MASS INDEX OF HEALTHCARE WORKERS
Authors: Camarinha Salome , Alves Helena , Abreu Diogo , Silva Laura , Pereira Miguel , Melo Daniel , Sardo Ana Paula , Mautempo Fernando 
Published: July 2024

Abstract

Introduction
It has been estimated that 38% of the world’s adult population will be obese by 2030. Obese workers have more lost workdays than workers with normal body mass index (BMI), independently of other risk factors. This study aims to analyse the BMI of hospital healthcare workers (HCW) through a descriptive analysis of their characteristics like gender, age and professional group.

Methods
A cross-sectional study was performed using data collected from the Occupational Medicine Department records. The study population included all HCW who were actively working at a Hospital Centre in 2022, and who had at least one BMI measurement between 2018 and 2022.

Results
This study included 1522 HCW. The mean age was 46±11 years and most were women (81.08%). The average BMI was 25.21±4.64 kg/m2, with a measurement range between 15.2 and 55.5 kg/m2. Most workers (52.50%) had a BMI within the normal range; 31.80% were overweight and 13.40% were obese. BMI was higher in males (26.08±3.53 kg/m2). HCW older than 39 years had a mean BMI equal or higher than 25.20±4.53 kg/m2. Hospital aides (27.03±5.0 kg/m2) had the highest mean BMI while diagnostic and therapeutic technicians had the lowest (24.08±4,02 kg/m2).

Discussion
This descriptive analysis shows that the study population had a mean BMI equivalent to overweight. Higher BMI are observed in males, older individuals and hospital aides.

Conclusion
Occupational Medicine may play a key role in identifying workers at greater risk and applying weight control measures, as a strategy to prevent obesity-related diseases and, ultimately, to reduce work absenteeism.
P-146 OCCUPATIONAL HEALTH RESEARCH IN THE UK: OPPORTUNITIES AND BARRIERS FOR DATA LINKAGES
Authors: Van Tongeren Martie , Demou Evangelia , Stevelink Sharon , Boyd Andrew 
Published: July 2024

Abstract

Introduction
One of the main historical challenges in the UK for occupational health research to inform and support the HSE policy activities is the lack of good quality occupational data in routinely collected health records.

Methods
We evaluated the breadth of data potentially available for occupational health research in the UK relating both to the exposures of interest (occupation and employment) and the health outcomes of interest (primarily stress and mental health, but also physical health outcomes, such as musculoskeletal and respiratory diseases, and cancers). In addition, we carried out interviews with stakeholders on the data needs/requirements and opportunities provided through data linkages.

Results
Key data sets were identified, such as the recently developed Public Health Data Asset and the Office of National Statistics Longitudinal Study, both of which have not been used extensively for occupational health research. The interviews provided important information on the opportunities for linking data sets such as the Labour Force Survey and the Annual Survey of Hours and Earnings (ASHE).

Discussion
Important new data opportunities for occupational health research in the UK have been identified as well as a number of barriers in terms of priorities and resources. However, further improvements could be made through encouraging inclusion of occupational data in routine health records.

Conclusion
We will next plan to develop a data platform specifically to facilitate occupational health research in the UK.
P-147 HEMOLYMPHOEPOIETIC CANCER AND OCCUPATIONAL EXPOSURE: PROPORTIONAL MORTALITY RATIO STRATIFIED BY PERMANENCE IN THE OCCUPATIONAL SECTOR
Authors: D’Elia Silvia , Massari Stefania , Gariazzo Claudio , Marinaccio Alessandro 
Published: July 2024

Abstract

Introduction
Blood and lymphatic tumors represent about 7% of all new cancer diagnoses in Italy. The occupational component plays an important role in their etiology.

Objective
The goal of the study is to assess the excess risk of hemolymphoepoietic cancer in occupational sectors and how it varies in terms of working days in a specific area of employment.

Methods
The Italian national statistical institute archive of the causes of death for the years 2005 – 2018 has been integrated with the National Social Insurance Agency contribution archives, referring only to the private sector starting from the 1974 for analysing the occupational history of deceased. The Proportional Mortality Ratio (PMR) was calculated by specific cause and sector considering the services sector as the reference. Age-adjusted PMRs were estimated using a generalized linear model (GLM) with a logarithmic link function. The 95% confidence interval was calculated for estimated risks. The analysis was implemented by stratifying by classes of permanence in the sector defined based on days of contributions.

Results
The dataset contains 25,883 males from 45 occupational sectors. Excess risk of myeloma is observed for the highest class of permanence in the mechanical engineering, mining, metals, iron, and steel industries. A positive trend in the excess risk of lymphoma was observed in the chemical, leather, wood, and printing sector; and of leukaemia in the health and veterinary service.

Discussion and conclusion
The substantial role of occupational risks in hemolymphoepoietic cancer is confirmed. A better understanding of the diseases etiology is essential for the prevention policies development.
O-093 REDUCING OCCUPATIONAL EXPOSURE TO PESTICIDES: UNDERSTANDING PREVENTION BEHAVIORS AMONG FRENCH FARMERS
Authors: Bresson Morgane , Bureau Mathilde , De Graaf Lucie , Leblanc Maylis , Lecluse Yannick , Baldi Isabelle , Lebailly Pierre , Bresson Morgane , Senemeaud Cécile , Lebailly Pierre 
Published: July 2024

Abstract

Introduction
Preventing farmers’ exposure to pesticides is a major public health issue. Wearing personal protective equipment (PPE) is one effective means of prevention among others. However, available data show that PPE are not always used by farmers. The aim of this study is to investigate the structural and psychosociological determinants of PPE use, in order to identify ways of improving farmer training.

Methods
163 French farmers (winegrowers or open-field farmers) responded to a telephone survey. The questionnaire was divided into 12 parts, covering pesticide knowledge, psychological constructs (beliefs, attitudes, social norms, self-efficacy, health locus of control), and individual and professional aspects. The association with the PPE use (gloves, body protection) was studied by logistic regression.

Results
Participants were males, farm owners (82%), average age 50, had a low education level (59%), a pesticide certificate (92%), reported performing all their treatments (80%) and using gloves more systematically (60%) than body protection (20%). PPE use was associated with low barriers perceived to self-protection, high perception that peers protect themselves (descriptive social norms) but not with knowledge levels. Body protection use was associated with being a winegrower, working on small farms, high perceived ability to protect oneself and thinking that peers or family expect them to protect themselves (subjective social norms).

Discussion and conclusion
Determinants of other behaviours (hand washing, product label reading) will be analysed. This analysis enabled us to consider ways of improving farmer training: practical work to reduce perceived barriers and improve perceived ability to use PPE, discussion groups or peer training to change perceived social norms.