bluuebunny/crossref_metadata_2025_split huggingface dataset:
Recombination and selection trajectory of the monkeypox virus during its adaptation in the human population
Authors: Zheng Jialu , Zeng Jinfeng , Long Haoyu , Chen Jian , Liu Kaijie , Chen Yixiong , Du Xiangjun 
Published: July 2024

AbstractMonkeypox, caused by the monkeypox virus (MPXV), was historically confined to West and Central Africa but has now spread globally. Recombination and selection play crucial roles in the evolutionary adaptation of MPXV; however, the evolution of MPXV and its relationship with the recent, ground‐breaking monkeypox epidemic remains poorly understood. To gain insights into the evolutionary dynamics of MPXV, comprehensive in silico recombination and selection analyses were conducted based on MPXV whole genome sequence data. Three types of recombination were identified: five ancestor‐sharing interspecies recombination events, six specific interspecies recombination events and four intraspecies recombination events. The results highlight the prevalent occurrence of recombination in MPXV, with 73.3% occurring in variable regions of the genome. Selection analysis was performed from three dimensions: proteins around recombination regions, proteins from recombinant ancestors and MPXV branches, and whole‐genome gene analysis. Results revealed 2 and 7 proteins under positive selection in the first two dimensions, respectively. These proteins are mainly involved in infection immunity, apoptosis regulation and viral virulence. Whole‐genome analysis detected 25 genes under positive selection, mainly associated with immune response and viral regulation. Understanding their evolutionary patterns will help predict and prevent cross‐species transmission, zoonotic outbreaks and potential human epidemics.
Transverse interlaminar ultrasound‐guided C1‐C2 puncture for the intrathecal administration of nusinersen in patients with spinal muscular atrophy
Authors: Yuan Qing , Cui Xulei , Zhang Jiao , Dai Yi , Feng Feng , Huang Yuguang , Zhang Shuyang 
Published: July 2024

AbstractIntroduction/AimsSevere spinal deformities and previous spinal orthopedic instrumentation may result in substantial technical challenges for nusinersen delivery through lumbar puncture in patients with spinal muscular atrophy (SMA). The aim of this paper was to review our experience with ultrasound‐guided cervical puncture as an alternative approach for the intrathecal administration of nusinersen.MethodsThis was a retrospective medical record review of transverse interlaminar ultrasound‐guided C1‐C2 puncture for nusinersen delivery in SMA patients. The details of puncture, complications, and success rate of the procedure were summarized.ResultsThere were four patients who received a total of 13 cervical punctures for nusinersen delivery. All procedures were technically successful with no major complications. Full doses of nusinersen were delivered intrathecally.DiscussionTransverse interlaminar ultrasound‐guided C1‐C2 puncture is an alternative approach for administering nusinersen if lumbar puncture fails. The success of the technique requires a thorough preprocedural evaluation of cervical spine imaging, sound knowledge of the cervical sonoanatomy and careful manipulation of the needle.
Nonlinear Effect Analysis and Sensitivity Improvement in Spin Exchange Relaxation Free Atomic Magnetometers
Authors: Xing Bozheng , Ma Ning , Lv Haoran , Lu Jixi 
Published: July 2024

AbstractIn this study, the influence of the nonlinear magneto–optical rotation effect on a spin‐exchange relaxation‐free (SERF) atomic magnetometer is analyzed. The nonlinear effect is described by saturation parameters obtained from the density matrix model considering the Rabi oscillation of the probe light. For better sensitivity, the nonlinear effect is suppressed, and larger output signals are achieved. Based on the nonlinear effect analysis, the relationship between the probe sensitivity and light power density is obtained, and the optimal probe light power density is measured with best probe sensitivity. The best probe sensitivity improves by ≈6 times at the optimal probe light power density compared with that in the conventional linear optical rotation detection. The proposed method can be applied to SERF magnetometers, co‐magnetometers, and atomic spin gyroscopes.
Periodic event‐triggered output feedback regulation for feedforward nonlinear systems with unknown measurement sensitivity
Authors: Zhang Wenjie , Liu Qingrong , Zhang Xianfu 
Published: July 2024

AbstractThis article addresses the global regulation by periodic event‐triggered output feedback control for a class of feedforward nonlinear systems. Particularly, the considered systems suffer from parameter uncertainties and unknown measurement sensitivity, which entail integrating advanced compensation strategies within the event‐triggered framework. To this end, a time‐varying gain is devised to tackle uncertain nonlinearities as well as the sampling error. Subsequently, a novel periodic event‐triggered output feedback controller is constructed based on the delicate choice of design parameters. Notably, the proposed control scheme is able to avoid the continuous monitoring of the system behavior, and guarantee that all closed‐loop system states are globally bounded and ultimately converge to zero. Finally, a practical example is given to illustrate the main results.
Semiotics for Actor-Network Theory
Authors: Peverini Paolo 
Published: July 2024

AbstractThis chapter aims to show how the relationship between Latour's investigation on meaning and the research perspective on signification developed within the framework of structural semiotics is anything but episodic, marginal or outdated. With the aim of highlighting the reasons behind an uninterrupted dialogue, even if often denied or marginalised in the field of social sciences, this chapter considers the main semiotic concepts at the basis of Latour’s work, highlighting the main affinities and discontinuities that emerge at a theoretical and methodological level, with particular reference to actor-network theory. It is pointed out that the metaphor of semiotics as a toolbox for actor-network theory is overly reductive and does not sufficiently account for the presence of a common non-anthropomorphic theory of agency and an anti-dualist epistemological principle that recognizes the primacy of the relationship over the elements involved in a social phenomenon. To this end, a comparison is made between the notions of actor, actant, enunciation, narrative program originally elaborated within the framework of semiotic theory and their novel reinterpretation introduced by Latour to examine the paradoxes of modernity.
Introduction
Authors: Aggestam Karin , Rosamond Annika Bergman , Hedling Elsa 
Published: July 2024

AbstractThis chapter introduces the study of the politics of feminist foreign policy and digital diplomacy. It unpacks two transformative and intersecting developments: (1) Sweden’s adoption of a distinct feminist branding of its foreign policy and (2) the embrace of digitalisation in diplomacy. In 2014, Sweden made history by becoming the first country in the world to launch a feminist foreign policy. This pioneering political move demanded both visibility and global attention, prompting Sweden to explore new digital environments and social media platforms, which would offer both scale and reach. Subsequently, several other states followed suit, embracing Sweden’s feminist foreign policy as a model of foreign policy conduct. This feminist shift in global politics has given rise to contestation, resistance and rejection by a range of global actors. This chapter advances a novel conceptual framework for studying the relationship between feminist foreign policy and digital diplomacy. The framework employs three key concepts: (a) articulation, (b) resonance and (c) contestation. These concepts are used to analyse Sweden’s feminist foreign policy leadership, nation branding and visual representation in global politics.
The Politics of Feminist Foreign Policy and Digital Diplomacy: Leadership, Branding and Visuality
Authors: Aggestam Karin , Rosamond Annika Bergman , Hedling Elsa 
Published: July 2024

AbstractThis chapter examines the interplay between digital diplomacy and feminist foreign policy by advancing a theoretical framework based on three key processes of politicisation: (a) articulation, (b) resonance and (c) contestation. This framework captures the fluctuation between antagonistic and agonistic political dynamics and the interplay between digital diplomacy and foreign policy. It highlights how these dynamics shape how states navigate, influence and respond to global developments. More specifically, the framework analyses these political dynamics and processes within three core foreign policy and diplomacy domains: (a) leadership, (b) branding and (c) visuality. As such, it seeks to explain why, how and in what ways the politics of digital diplomacy and feminist foreign policy are pursued, practised and perceived in contemporary global politics.
Political Leadership and the Digital Diffusion of Feminist Foreign Policy
Authors: Aggestam Karin , Rosamond Annika Bergman , Hedling Elsa 
Published: July 2024

AbstractThis chapter examines the role of political leadership and the utilisation of digital diplomacy in advancing the norms and objectives of feminist foreign policy. It explores the various roles that leaders play in the political articulation, resonance and contestation of feminist foreign policy in the digital realm. It specifically analyses how and in what ways former Swedish foreign minister Margot Wallström actively engaged, as a norm entrepreneur, in efforts to garner political support for Sweden’s feminist foreign policy, while disseminating a feminist vision of a more gender-just world order to global online audiences. Moreover, the chapter examines how Wallström strategically articulated Sweden’s feminist foreign policy as a prioritised agenda and the international resonance it elicited, particularly evidenced by the positive responses of states such as Canada and Germany. Finally, the chapter elucidates the ramifications of political leadership and gendered contestation on social media by analysing Sweden’s role in the #shedecides digital campaign. This campaign was triggered in response to the reinstatement of the US global gag rule by the Trump Administration, which sought to restrict the sexual and reproductive rights of girls and women worldwide.
Visuality, Digital Visibility and Feminist Foreign Policy
Authors: Aggestam Karin , Rosamond Annika Bergman , Hedling Elsa 
Published: July 2024

AbstractIn this chapter, we explore how online opportunities, emerging from visual language, symbolic representation and global visibilities productively diffused the communication of Sweden’s feminist foreign policy to global audiences. The launch and trajectory of Sweden’s feminist foreign policy involved the management of visual representations and close navigation of the visual saturation of the contemporary political information environment. The reach and resonance of Sweden’s feminist foreign policy were strengthened by the political mobilisation and employment of a range of visual representations and visibility structures. This chapter analyses the use of visual language in the political articulation of Sweden’s feminist foreign policy. To this effect, we provide a visual analysis of a photo exhibition that became a successful conversation, enabling the connection between the global goals of feminist foreign policy with wider gender debates that resonated with a range of national settings. Finally, we analyse the WikiGap initiative, which aimed to enhance the visibility of women’s stories and experiences online. The initiative illustrates how Sweden’s contestation of gendered politics was made visible online.
The SemGuS Toolkit
Authors: Johnson Keith J. C. , Reynolds Andrew , Reps Thomas , D’Antoni Loris 
Published: July 2024

AbstractSemantics-Guided Synthesis (SemGuS) is a programmable framework for defining synthesis problems in a domain- and solver-agnostic way. This paper presents the standardized SemGuS format, together with an open-source toolkit that providesa parser, a verifier, and enumerative SemGuS solvers. The paper also describes an initial set of SemGuS benchmarks, which form the basis for comparing SemGuS solvers, and presents an evaluation of the baseline enumerative solvers.
QReach: A Reachability Analysis Tool for Quantum Markov Chains
Authors: Dai Aochu , Ying Mingsheng 
Published: July 2024

AbstractWe present QReach, the first reachability analysis tool for quantum Markov chains based on decision diagrams CFLOBDD (presented at CAV 2023). QReach provides a novel framework for finding reachable subspaces, as well as a series of model-checking subprocedures like image computation. Experiments indicate its practicality in verification of quantum circuits and algorithms. QReach is expected to play a central role in future quantum model checkers.
Stroke Evaluation in the Interventional Suite Using Dual-Layer Detector Cone-Beam CT: a First-in-human Prospective Cohort Study (the Next Generation X-ray Imaging System Trial)
Authors: Ståhl Fredrik , Almqvist Håkan , Aspelin Åsa , Kolloch Jens , Ghalamkari Odett , Gontu Vamsi , Schäfer Dirk , van de Haar Peter , Engel Klaus-Jürgen , van Nijnatten Fred , Holmberg Åke , Mazya Michael V. , Söderman Michael , Delgado Anna Falk 
Published: July 2024

Abstract
Purpose
Cone-beam CT in the interventional suite could be an alternative to CT to shorten door-to-thrombectomy time. However, image quality in cone-beam CT is limited by artifacts and poor differentiation between gray and white matter. This study compared non-contrast brain dual-layer cone-beam CT in the interventional suite to reference standard CT in stroke patients.

Methods
A prospective single-center study enrolled consecutive participants with ischemic or hemorrhagic stroke. The hemorrhage detection accuracy, per-region ASPECTS accuracy and subjective image quality (Likert scales for gray-white matter differentiation, structure perception and artifacts) were assessed by three neuroradiologists blinded to clinical data on dual-layer cone-beam CT 75 keV monoenergetic images compared to CT. Objective image quality was assessed by region-of-interest metrics. Non-inferiority for hemorrhage detection and ASPECTS accuracy was determined by the exact binomial test with a one-sided lower performance boundary prospectively set to 80% (98.75% CI).

Results
27 participants were included (74 years ± 9; 19 female) in the hyperacute or acute stroke phase. One reader missed a small bleeding, but all hemorrhages were detected in the majority analysis (100% accuracy, CI lower boundary 86%, p = 0.002). ASPECTS majority analysis showed 90% accuracy (CI lower boundary 85%, p < 0.001). Sensitivity was 66% (individual readers 67%, 69%, and 76%), specificity was 97% (97%, 96%, 89%). Subjective and objective image quality were inferior to CT.

Conclusion
In a small single-center cohort, dual-layer cone-beam CT showed non-inferior hemorrhage detection and ASPECTS accuracy to CT. Despite inferior image quality, the technique may be useful for stroke evaluation in the interventional suite.

Trial Registration Number
NCT04571099 (clinicaltrials.gov). Prospectively registered 2020-09-04.
New sea urchins (Echinodermata: Echinoidea) from the Famennian of Velbert (W Germany): Evidence for echinoid faunal turnover in the Late Devonian
Authors: Pauly Luis , Haude Reimund 
Published: July 2024

AbstractDespite the presumably lower diversity of Palaeozoic echinoids compared to their post-Palaeozoic relatives, a radiation during the Mississippian marked a first brief "golden age" of sea urchins. Carboniferous echinoid faunas feature distinct and specialised groups compared to those of the Devonian, suggesting important evolutionary changes during the Late Devonian, although the role of biotic crises like the Kellwasser and Hangenberg Events in these changes remains poorly known. This study describes an exceptionally well-preserved echinoid fauna from the middle to upper Famennian of Velbert near Düsseldorf, Germany. Description of six new species belonging to the lepidocentrid, hyattechinid, proterocidarid and archaeocidarid lineages along with a seventh species based on isolated remains greatly add to the knowledge of Late Devonian echinoids. The newly described genera Thielechinus gen. nov. and Velbertechinus gen. nov. represent the most derived proterocidarids and archaeocidarids known from the pre-Carboniferous. Moreover, the fossils offer new insights into phylogeny, ontogeny, and palaeobiology of several stem-group echinoid lineages. The fauna resembles Carboniferous echinoid faunas much more than earlier Devonian faunas, thus providing evidence that crucial developments had occurred from the Frasnian to the Famennian, possibly linked to global changes associated with the catastrophic Kellwasser Event. These developments include the appearance of several specialised lineages that would become important in the Late Palaeozoic as well as evolutionary innovations leading up to the establishment of the crown-group echinoid body plan.
A circadian rhythm-related lncRNA signature correlates with prognosis and tumor immune microenvironment in head and neck squamous cell carcinoma
Authors: Zheng Hongyu , Li Qiuyue , Yang Kai 
Published: July 2024

Abstract
Objective
To investigate circadian rhythm-associated long non-coding RNA (lncRNA) signatures in predicting prognosis, metabolism, and immune infiltration in Head and Neck Squamous Cell Carcinoma (HNSC).

Methods
HNSC samples were collected from the TCGA database. A signature was constructed using Cox regression and Least Absolute Shrinkage and Selection Operator (LASSO) methods. The immune cell infiltration was analyzed using CIBERSORT, ssGSEA, and MCPcounter. The RT-qPCR was used to detect the expression of signature lncRNAs.

Results
A signature comprising 8 lncRNAs was constructed. The constructed signature demonstrated good prognostic prediction capability for HNSC. A nomogram encompassing risk score accurately predicted the long-term OS probability of HNSC. The infiltration levels of T cell, B cell and Macrophages were significantly higher in the high-risk group than in the low-risk group. Cluster analysis showed that the signature lncRNAs could classify the HNSC samples into two clusters. The RT-qPCR suggested that the expression of lncRNAs in signature was consistent with the data in TCGA.

Conclusion
The circadian rhythm-associated lncRNA signature has potential as a prognostic indicator for HNSC. It exhibits associations with metabolism, immune microenvironment, and drug sensitivity, thereby providing valuable insights for informing the treatment of HNSC.
Looking for Improving the Urban Areas: the Case of Costa Rican Cantons in Their Path to Become Smart
Authors: Rodríguez Bolívar Manuel Pedro , Pereira-Piedra Isabel Cristina , Alcaide Muñoz Laura 
Published: July 2024

AbstractThe process of becoming a smart city (SC) is still diffuse due to the contextual factors and urban challenges that local governments must face, so it is necessary to visualise new options and city strategies to implement them. This study contributes to prior research offering new insights concerning patterns used by small-sized cities in a developing and emerging country in the Latin American context (LATAM) in their early stages of becoming smart, analysing the dimensions to be developed, their pursued goals, their desired economic and/or social impacts, and the time frames expected to reach them. Our findings, based on cluster analysis and Kendall’s TAU C correlation, confirm differences in city strategies according to the contextual challenges faced by cities emphasising three different governance models to become smart based on the different significance given to the three components of the smart governance concept. The different city clusters point out different correlations among their priority goals and the smart dimensions, showing a different position of the cities in the smart dimensions’ development and goals. Also, differences in expected time frames to reach the aspired goals are identified. These findings allow us to derive new theoretical and managerial implications for cities on their path to become smart.
Metal–Organic Framework-Based Photodetectors
Authors: Zhang Jin-Biao , Tian Yi-Bo , Gu Zhi-Gang , Zhang Jian 
Published: July 2024

AbstractThe unique and interesting physical and chemical properties of metal–organic framework (MOF) materials have recently attracted extensive attention in a new generation of photoelectric applications. In this review, we summarized and discussed the research progress on MOF-based photodetectors. The methods of preparing MOF-based photodetectors and various types of MOF single crystals and thin film as well as MOF composites are introduced in details. Additionally, the photodetectors applications for X-ray, ultraviolet and infrared light, biological detectors, and circularly polarized light photodetectors are discussed. Furthermore, summaries and challenges are provided for this important research field.
Interpenetrated Structures for Enhancing Ion Diffusion Kinetics in Electrochemical Energy Storage Devices
Authors: Xue Xinzhe , Feng Longsheng , Ren Qiu , Tran Cassidy , Eisenberg Samuel , Pinongcos Anica , Valdovinos Logan , Hsieh Cathleen , Heo Tae Wook , Worsley Marcus A. , Zhu Cheng , Li Yat 
Published: July 2024

AbstractThe architectural design of electrodes offers new opportunities for next-generation electrochemical energy storage devices (EESDs) by increasing surface area, thickness, and active materials mass loading while maintaining good ion diffusion through optimized electrode tortuosity. However, conventional thick electrodes increase ion diffusion length and cause larger ion concentration gradients, limiting reaction kinetics. We demonstrate a strategy for building interpenetrated structures that shortens ion diffusion length and reduces ion concentration inhomogeneity. This free-standing device structure also avoids short-circuiting without needing a separator. The feature size and number of interpenetrated units can be adjusted during printing to balance surface area and ion diffusion. Starting with a 3D-printed interpenetrated polymer substrate, we metallize it to make it conductive. This substrate has two individually addressable electrodes, allowing selective electrodeposition of energy storage materials. Using a Zn//MnO2 battery as a model system, the interpenetrated device outperforms conventional separate electrode configurations, improving volumetric energy density by 221% and exhibiting a higher capacity retention rate of 49% compared to 35% at temperatures from 20 to 0 °C. Our study introduces a new EESD architecture applicable to Li-ion, Na-ion batteries, supercapacitors, etc.