bluuebunny/crossref_metadata_2025_split huggingface dataset:
Poetry in the Service of Music: The Case of Giovambattista Strozzi the Younger (1551–1634)
Authors: Chater James 
Published: January 2013

Giovambattista (G. B.) Strozzi the Younger (1551–1634) occupied an important place in the literary life of Florence during the period when the Medici were consolidating their absolute rule over Tuscany. As a founder member and host of the Accademia degli Alterati he stands at the center of a web of poets and academicians who strove to bring about a closer cooperation between music, literature, and theater.
Strozzi is of interest to music historians for his work in three overlapping areas. First, he provided the texts for intermedi, maschere, and other music performed in Florence from 1579 until 1608, including music celebrating dynastic events of the Medici family. Second, a number of his poems were disseminated as the texts of published madrigals. Third, G. B. Strozzi is the author of poesia per musica, poems written specifically for musical setting or as contrafacta for existing musical pieces. In this area Strozzi was influenced by the reforming and moralizing tendencies of the Congregazione dell’Oratorio.
This article surveys Strozzi’s contribution in these three overlapping areas and also focuses on the poems Strozzi wrote in homage to Bianca Cappello, Francesco de’ Medici’s mistress and later his wife.
IOM Review of FDA-Approved Biologics Labeled or Studied for Pediatric Use
Authors: Field Marilyn J. , Ellinger Lara K. , Boat Thomas F. 
Published: January 2013

BACKGROUND:
Studies have examined the extent to which public policies such as the Best Pharmaceuticals for Children Act have increased pediatric information in drug labeling. Little attention has focused on pediatric labeling of biologics. This analysis examines the extent to which biologics are labeled for pediatric use or have been studied in children.

METHODS:
The analysis covers the 96 biologics (excluding vaccines) that were first licensed by the Food and Drug Administration between 1997 and 2010 and were still marketed as of 2010. Product labeling was consulted for information on approved pediatric uses, pediatric studies, or pediatric safety warnings based on analyses of adverse events. The online database ClinicalTrials.gov was searched for registered pediatric studies of these biologics. A separate analysis examined labeling and studies for 55 vaccines.

RESULTS:
For ∼60% of the 96 biologics, labeling shows approved pediatric use or pediatric study information or both. Approximately 85% of the biologics have ≥1 registered pediatric trial completed, underway, or planned. Overall, ∼90% are labeled for pediatric use, have pediatric information in the label, have a registered pediatric study, or have some combination of these characteristics. For the 55 analyzed vaccines, the corresponding figure is 95%.

CONCLUSIONS:
A majority of biologics approved in the past 15 years include some pediatric information in their labeling, and pediatric trials have been registered for a substantial majority of these products.
Dermis Reconstruction and Dermis Fat Graft through an Intraoral Incision: A New Method to Correct the Furrowed Philtral Column Deformity in Lesser-Form Cleft Lip
Authors: Wang Youbin , Qi Zheng , Wang Xiaojun 
Published: January 2013

Objective Minor cleft lip deformities are also called lesser-form cleft lips. A furrowed philtral column is one of the important characters of these deformities. Many surgical methods have been adopted to correct it with less than satisfactory results. In this article, a dermis reconstructive method was introduced. Patients From 2003 to 2010, 35 patients with lesser-form cleft lip were treated in our center. Interventions Through an intraoral and vermilion incision, the oral side of the orbicularis oris muscle on the affected side was dissected. Through a vermilion and perialar incision, the dermal side of the orbicularis oris muscle was dissected along the furrow. After restoring orbicularis oris muscular ring continuity, if necessary, the underdeveloped dermis was reconstructed with three sutures along the furrow. To reinforce lip thickness on the affected side and increase the philtral column prominence, retroauricular dermis fat was grafted between the muscle and skin. Results Thirty-five patients with lesser-form cleft lip were treated with dermis reconstruction and retroauricular dermis fat grafts. Congenital lip depressions were well corrected, and the philtral column prominences were reconstructed. The follow-up period was 6 to 20 months. All patients were satisfied with their results. Conclusion Dermis reconstruction and dermis fat grafting through an intraoral incision is effective in repairing a furrowed philtral column deformity in lesser-form cleft lip.
Lactoferrin Knockout Mice Demonstrates Greater Susceptibility to Aggregatibacter actinomycetemcomitans–Induced Periodontal Disease
Authors: Velusamy S.K. , Ganeshnarayan K. , Markowitz K. , Schreiner H. , Furgang D. , Fine D.H. , Velliyagounder K. 
Published: January 2013

Background: Among the innate defense mechanisms in the oral cavity, lactoferrin (LF) is a vital antimicrobial that can modify the host response against periodontopathogens. Aggregatibacter actinomycetemcomitans is the main periodontopathogen of localized aggressive periodontitis. The aim of this study is to evaluate the role of LF during A. actinomycetemcomitans–induced periodontitis.Methods: Differences in the expression levels of cytokines, chemokines, chemokine receptors, and bone loss markers between wild‐type (WT) and LF knockout mice (LFKO−/−) were evaluated by real time‐PCR. Serum IgG and LF levels were quantified by ELISA. Alveolar bone loss among the groups was estimated by measuring the distance from cemento‐enamel junction (CEJ) to the alveolar bone crest (ABC) at 20 molar sites.Results: Oral infection with A. actinomycetemcomitans increased LF levels in periodontal tissue (P = 0.01) and saliva (P = 0.0004) of wild‐type infected (WTI) mice compared to wild‐type control mice. Pro‐inflammatory cytokines such as interferon‐γ, tumor necrosis factor‐α, interleukin (IL)‐1β, IL‐6, and IL‐12 were increased in the infected LF knockout (LFKO−/−I) mice compared to the WTI mice, whereas the anti‐inflammatory cytokines IL‐4 and IL‐10 were decreased. Chemokines and chemokine receptors showed different expression patterns between WTI and LFKO−/−I mice. The LFKO−/−I mice developed increased bone loss (P = 0.002), in conjunction with increased expression of receptor activator of nuclear factor‐κB ligand and decrease in osteoprotegerin, compared to WTI mice.Conclusions: These results demonstrate that the infected LFKO−/− mice were more susceptible to A. actinomycetemcomitans–induced alveolar bone loss, with different patterns of immune responses compared to those of WTI mice.
Suppuration‐Associated Bacteria in Patients With Chronic and Aggressive Periodontitis
Authors: Silva‐Boghossian Carina M. , Neves Aline B. , Resende Fátima A.R. , Colombo Ana Paula V. 
Published: January 2013

Background: Suppuration (SUP) on probing may be an indication of active periodontal breakdown. The aim of the present study is to analyze which subgingival species are associated with SUP in patients with chronic (CP) and aggressive (AgP) periodontitis.Methods: A total of 156 patients with CP and 66 with AgP were submitted to full‐mouth periodontal examination and subgingival biofilm sampling (14 sites/patient). The counts of 44 bacterial species were determined by checkerboard. Comparisons between groups and sites were analyzed by the Mann‐Whitney and Wilcoxon tests, respectively. Associations between frequency of SUP and bacterial species were analyzed by the Spearman correlation coefficient.Results: The prevalence of SUP in patients with CP was 24.4%, and in patients with AgP it was 30.3%, and the percentage of SUP sites in the groups was 5.72% ± 1.06% and 6.96% ± 1.70%, respectively (P >0.05). SUP sites from patients with CP had significantly higher counts of Veillonella parvula, Dialister pneumosintes, Tannerella forsythia, and Prevotella nigrescens than SUP sites from patients with AgP (P <0.005). Significant positive correlations between high frequency of SUP and high levels of Actinomyces spp, Streptococcus spp., members of the orange complex, Acinetobacter baumannii, and Pseudomonas aeruginosa were observed in patients with CP (P <0.05). In patients with AgP, Actinomyces oris, Propionibacterium acnes, P. aeruginosa, Staphylococcus aureus, and Streptococcus sanguinis were positively associated with SUP, whereas Prevotella intermedia presented a negative association with SUP (P <0.05).Conclusions: SUP sites from patients with CP harbored significantly higher counts of several periodontal species than SUP sites from patients with AgP. Actinomyces spp., Streptococcus spp., members of the orange complex, T. forsythia, and certain non‐oral pathogens were associated with a high number of sites with SUP.
Cooking and Eating Facilities in Migrant Farmworker Housing in North Carolina
Authors: Quandt Sara A. , Summers Phillip , Bischoff Werner E. , Chen Haiying , Wiggins Melinda F. , Spears Chaya R. , Arcury Thomas A. 
Published: January 2013

Objectives. We sought to (1) describe observed cooking and eating facilities in migrant farmworker camps, (2) compare observed conditions with existing farmworker housing regulations, and (3) examine associations of violations with camp characteristics. Methods. We collected data in 182 farmworker camps in eastern North Carolina during the 2010 agricultural season. We compared our observations with 15 kitchen-related housing regulations specified by federal and state housing standards. Results. We observed violations of 8 regulations in at least 10% of camps: improper refrigerator temperature (65.5%), cockroach infestation (45.9%), contaminated water (34.4%), rodent infestation (28.9%), improper flooring (25.8%), unsanitary conditions (21.2%), improper fire extinguisher (19.9%), and holes or leaks in walls (12.1%). Logistic regression showed that violations were related to the time of the agricultural season, housing type, number of dwellings and residents, and presence of workers with H-2A visas. Conclusions. Cooking and eating facilities for migrant farmworkers fail to comply with regulations in a substantial number of camps. Greater enforcement of regulations, particularly during occupancy during the agricultural season, is needed to protect farmworkers.
Cigarette Smoking and Onset of Mood and Anxiety Disorders
Authors: Mojtabai Ramin , Crum Rosa M. 
Published: January 2013

Objectives. We examined the association between regular cigarette smoking and new onset of mood and anxiety disorders. Methods. We used logistic regression analysis to detect associations between regular smoking and new-onset disorders during the 3-year follow-up among 34 653 participants in the longitudinal US National Epidemiologic Survey on Alcohol and Related Conditions (2001–2005). We used instrumental variable methods to assess the appropriateness of these models. Results. Regular smoking was associated with an increased risk of new onset of mood and anxiety disorders in multivariable analyses (Fdf = 5,61 = 11.73; P < .001). Participants who smoked a larger number of cigarettes daily displayed a trend toward greater likelihood of new-onset disorders. Age moderated the association of smoking with most new-onset disorders. The association was mostly statistically significant and generally stronger in participants aged 18 to 49 years but was smaller and mostly nonsignificant in older adults. Conclusions. Our finding of a stronger association between regular cigarette smoking and increased risk of new-onset mood and anxiety disorders among younger adults suggest the need for vigorous antismoking campaigns and policy initiatives targeting this age group.
Flow of Hydrophobically Modified Water-Soluble Polymers in Porous Media: Controlled Resistance Factors vs. Flow-Induced Gelation in the Semidilute Regime
Authors: Dupuis Guillaume , Rousseau David , Tabary René , Grassl Bruno 
Published: January 2013

Summary
The associative properties of hydrophobically modified water soluble polymers (HMWSPs) are attractive for improved oil recovery (IOR) because of both their enhanced thickening capability, compared with classical water-soluble polymers (for mobility-control applications), and their permeability-reduction, or plugging, ability (for well-treatment applications). In previous works, we have studied the injectivity of HMWSP made of sulfonated polyacrylamide backbones and alkyl side chains in the dilute regime and have shown, in particular, that it was largely governed by adsorption. In this paper, we report new experimental data on the injectivity of the same class of HMWSP solutions in the semidilute regime.
From membrane filtration tests at imposed flow rate, we have first observed the formation of a filter cake made of HMWSP physical gel, which remained largely permeable to polymers. Our observations are compatible with the creation of channels within the gel. This leads to a gel-filtration process, entailing modifications of the solution's viscosimetric properties, which can be explained by a rearrangement of the intra- and interchain hydrophobic bonds in the solution. The second part of our work consisted of injectivity tests in model granular packs. We have performed comparative experiments in porous media with variable permeabilities, but at the same shear rate in the pore throats. Results show that, above a critical permeability kC, or a critical pore-throat radius rpC, HMWSP injection led to stable resistance factors, with values close to the solution's viscosity, and that, at less than kC or rpC the very high resistance factors observed suggest that flow-induced gelation of the HMWSP takes place. Furthermore, resistance factors measured over the core internal sections are compatible with an in-depth formation of the gel. These insights could be of use for designing HMWSP better suited to mobility-control operations and for tuning HMWSP-injection conditions for profile/conformance-control operations.
Nonlinear Formulation Based on an Equation-of-State Free Method for Compositional Flow Simulation
Authors: Zaydullin R.. , Voskov D.V.. V. , Tchelepi H.A.. A. 
Published: January 2013

Summary
Compositional simulation is necessary for modeling complex enhanced oil recovery (EOR) processes. For accurate simulation of compositional processes, we need to resolve the coupling of the nonlinear conservation laws, which describe multiphase flow and transport, with the equilibrium phase behavior constraints. The complexity of the problem requires extensive computations and consumes significant time. This paper presents a new framework for the general compositional problem associated with multicomponent multiphase flow in porous media. Here, adaptive construction and interpolation using the supporting tie lines are used to obtain the phase state and the phase compositions. For the parameterization of the full solution of a complex compositional problem, we need only a limited number of supporting tie lines in the compositional space. The parameterized tie lines are triangulated using Delaunay tessellation, and natural-neighbor interpolation is used inside the simplexes. Then, the computation of the phase behavior in the course of a simulation becomes an iteration-free, table look-up procedure. The treatment of nonlinearities associated with complex thermodynamic behavior of the fluid is based on the new set of unknowns—tie-line parameters that allow for efficient representation of the subcritical region. For the supercritical region, we use the standard compositional variable set based on the overall composition.
The efficiency and accuracy of the method are demonstrated for several multidimensional compositional problems of practical interest. In terms of the computational cost of the thermodynamic calculations, the proposed method shows results comparable to those of state-of-the-art techniques. Moreover, the method shows better nonlinear convergence in the case of near-miscible gas-injection simulation.
Three-Phase Pore-Network Modeling for Reservoirs With Arbitrary Wettability
Authors: Al-Dhahli Adnan , Geiger Sebastian , van Dijke Marinus I.J. 
Published: January 2013

Summary
Oil reservoirs have structural heterogeneities across multiple length scales and, particularly in carbonates, complexly distributed wettabilities. The interplay of structural and wettability heterogeneities is the fundamental control for sweep efficiency and oil recovery. This interplay must be captured in physically robust flow functions, such as relative permeability and capillary pressure functions. Such flow functions then allow us to choose the best improved-oil-recovery (IOR) or enhanced-oil-recovery (EOR) process and forecast oil recovery with adequate precision. Obtaining flow functions for reservoir rocks with varying wettability is a challenging task, especially when three fluid phases coexist. In this work, we use pore-network modeling, a reliable and physically based simulation tool, to predict three-phase flow functions. We have developed a new pore-scale network model for rocks with variable wettability. Unlike other models, this model combines three new and important features. (1) Our network model comprises a novel thermodynamic criterion for the formation and collapse of oil layers. This captures film/layer flow of oil adequately, which affects the oil relative permeability at low oil saturation. We can therefore predict residual oil more accurately. (2) We implemented multiple displacement chains, in which injection of one phase at the inlet triggers a chain of interface displacements throughout the network. This allows us to accurately model the mobilization of disconnected phase clusters that arise during higher-order [water-alternating-gas (WAG)] floods. Again, this feature is key to a better prediction of residual oil saturation (ROS). (3) Our model takes realistic 3D pore networks extracted from pore-space reconstruction methods and X-ray computerized-tomography (CT) images as input. This preserves both topology and pore shape of the rock, providing better estimates of phase conductivities and relative permeability. We have validated our model by use of available experimental data for a range of wettabilities and demonstrated the impact of single vs. multiple displacement on residual oil. We also used a proof-of-concept study in which we use flow functions for different wettabilities that have been computed with our model in field-scale reservoir simulations to forecast oil recovery during tertiary gas injection. These results are compared with predictions that used empirical flow functions. Flow functions computed by our network model gave higher oil recovery than corresponding flow functions calculated by empirical models; oil recovery increases with decreasing water-wetness. This shows that the pore-scale physics encapsulated in our new network model leads to the right emergent behavior at the reservoir scale.
A Longitudinal Examination of Enterprise Resource Planning System Post-Implementation Enhancements
Authors: Cao Jian , Nicolaou Andreas I. , Bhattacharya Somnath 
Published: January 2013

ABSTRACT
Past information systems research on real options suggests that large-scale information technology projects, such as enterprise resource planning systems (ERPS), create various future options for system reconfiguration and extension. Management would decide whether to exercise an option according to future conditions. From the real options lens, we conduct a longitudinal examination of the determinants of post-implementation enhancement decisions for firms that have previously reported ERPS adoptions. We find that proactive ERPS adopters that employ performance-enhancing post-implementation review (PIR) practices and obtain favorable performance outcomes are more likely to make system enhancements. Evidence also shows that management likely makes joint decisions on PIR uses and ERPS enhancements, consistent with the view that managers perform gateway reviews at points where potential enhancement opportunities are present. Moreover, management tends to delay the enhancing decision until after the initial results are in place. Overall, our findings are consistent with the logic of real options, suggesting that managers make heuristic evaluations for general conditions that allow for future contingent investments.
Clinical Evaluation of Self-etch and Total-etch Adhesive Systems in Noncarious Cervical Lesions: A Two-year Report
Authors: Burgess JO , Sadid-Zadeh R , Cakir D , Ramp LC 
Published: January 2013

SUMMARY

Objective:
The purpose of this study was to compare the clinical performance of two self-etch dental adhesives with Single Bond Plus, a traditional one-bottle total-etch dental adhesive, for the restoration of noncarious cervical lesions.

Materials and Methods:
A total of 156 restorations were placed in noncarious cervical lesions with a minimum depth of 1.5 mm. Patients had no chronic periodontal disease and had normal salivary function. Each patient received restorations on three teeth, each bonded with either Adper Single Bond Plus, Adper Easy Bond, or Adper Scotchbond SE dental adhesive. All lesions were restored with Filtek Supreme Plus composite resin. All teeth were isolated with a rubber dam, received a short enamel bevel, and were cleaned with flour of pumice. The adhesives and resin composite were applied following the manufacturers' instructions. Restorations were clinically evaluated at baseline, six months, one year, and two years using modified US Public Health Service criteria.

Results:
Two-year retention was recorded as 97.3%, 90.5%, and 95.2%, for Single Bond Plus, Scotchbond SE, and Easy Bond, respectively. Statistical analysis did not show a significant difference (p&gt;0.05) in clinical performance between any of the three adhesives after a period of two years.
Effects of infrared camera angle and distance on measurement and reproducibility of thermographically determined temperatures of the distolateral aspects of the forelimbs in horses
Authors: Westermann Simone , Buchner Heinz H. F. , Schramel Johannes P. , Tichy Alexander , Stanek Christian 
Published: January 2013

Abstract
Objective—To assess effects of camera angle and distance on measurement and reproducibility of thermographically determined temperatures of the distolateral aspect of the forelimbs in horses.
Design—Evaluation study.
Animals—10 adult horses.
Procedures—Thermographic images of both forelimbs were obtained at 3 times during the day (replicates 1, 2, and 3); maximum surface temperature over 1 region (distolateral aspect of the third metacarpal bone and metacarpophalangeal joint) was measured. Standard images were obtained every 5 minutes for 1 hour with the camera positioned at an angle of 90° and a distance of 1.0 m from the forelimb; additional images were obtained at changed (± 20°) angles or at a 1.5-m distance. At the end of each replicate, 4 sets of additional images were obtained at 2-minute intervals to assess short-term reproducibility.
Results—Mean ± SD temperature difference between left and right forelimbs was 0.32° ± 0.27°C (0.58° ± 0.49°F) in standard images. Temperatures measured via standard images were highly correlated with those measured with the camera positioned at changed angles or distance. Mean ± SD differences between temperatures measured via standard images and those measured from changed angles or distance were considered small (≤ 0.22° ± 0.18°C [0.40° ± 0.32°F] for all comparisons). The degree of short-term reproducibility was high.
Conclusions and Clinical Relevance—Thermographically determined temperatures were unaffected by 20° changes in camera angle or a 0.5-m increase in camera distance from the forelimb. Minor temperature differences between left and right forelimbs were detected in the study and should be considered during diagnostic investigations.