bluuebunny/crossref_metadata_2025_split huggingface dataset:
Genotype-guided therapy improves initial acenocoumarol dosing
Authors: Cerezo-Manchado Juan Jose , Roldán Vanessa , Corral Javier , Rosafalco Mario , Antón Ana Isabel , Padilla Jose , González-Conejero Rocio , Vicente Vicente 
Published: November 2015

SummaryA few trials so far have evaluated the effectiveness of algorithms designed to calculate doses in oral anticoagulant therapy, with negative or contradictory results. We compared a genotype-guided algorithm vs physician management for the initiation of acenocoumarol. In a twoarm, prospective, randomised study with patients with atrial fibrillation who started therapy, the first dose was administered to all patients according to the physician’s criteria. At 72 hours, the corresponding dose was calculated based on INR in the standard care group (SC, N=92), whereas genetic data (VKORC1, CYP2C9 and CYP4F2) were also considered for the genotype-guided dosing (pharmacogenetic) group (PGx, N=87) by using an algorithm previously validated in 2,683 patients. The primary outcomes were: patients with steady dose, the time needed to reach the same and the percentage of therapeutic INRs. After 90 days, 25 % of the SC and 39 % of the PGx patients reached the steady dose (p=0.038). Kaplan-Meier analysis showed that PGx group needed fewer days to reach therapeutic INR (p=0.033). Additionally, PGx had a higher percentage of therapeutic INRs than SC patients (50 % and 45 %, respectively) (p=0.046). After six months the proportion of steadily anticoagulated patients remained significantly higher in PGx (p=0.010). In conclusion, genotype-guided dosing was associated with a higher percentage of patients with steady dose than routine practice when starting oral anticoagulation with acenocoumarol.
Mental health literacy in post-secondary students
Authors: Kutcher Stan , Wei Yifeng , Morgan Catherine 
Published: November 2015

Objectives: The transition from high school to college or university is an important time to enhance mental health literacy for young people. This study evaluated the second edition of a resource entitled Transitions, a comprehensive life-skills resource with embedded mental health information available in book, e-book and iPhone app formats for post-secondary students. Design: In this cross-sectional/one-off study, students’ opinions about the impact of the resource were gained through in-person and online surveying. Methods: The survey took place on a local university campus in Canada. Frequencies of responses and sex differences in answers were analysed using Predictive Analytics Software (PASW) 17. In total, 82 students from a large, Canadian research university completed the survey. Results: Reading Transitions (2nd edition) improved student knowledge about and decreased stigma towards mental health and mental illness and increased help-seeking efficacy. There were sex differences in response regarding discussion of the resource with others and help-seeking intentions. Conclusion: Given the positive results of this study conducted at a single university, the resource could potentially be valuable in other post-secondary settings as well.
Study protocol RapMusicTherapy for emotion regulation in a school setting
Authors: Uhlig Sylka , Jansen Erik , Scherder Erik 
Published: November 2015

The growing risk of the development of problem behaviors in adolescents (ages 10–15) requires effective methods for prevention, supporting self-regulative capacities. Music listening as an effective self-regulative tool for emotions and behavioral adaptation for adolescents and youth is widely studied. However, music therapy enhancing the development of emotion regulation skills in schools is rare. The application of rap in clinical cases of music therapy appears to have a beneficial regulative effect on this population. The aim of this study is to investigate the performance of RapMusicTherapy (RMT) in a non-clinical, school-based program to support self-regulative abilities for well-being and to reduce the risk of low grades attributable to troubled mental health at an early stage. All adolescents in Grade 8 of a public school will be invited to participate, and randomly assigned, either to RMT or to regular classes. RMT will be applied once a week during 4 months. After obtaining written informed consent by parents, measurements will take place at baseline (start of study), after 4 months (end of RMT) and again after 4 months without RMT (follow-up). Primary outcome data include measures of psychological well-being, emotion regulation, self-esteem, self-description, language development, executive functioning and the rest–activity rhythm. Secondary outcome data consist of subjective experiences of participants, collected in follow-up interviews with experimental group respondents. RMT is developed for application in school-based settings. This is the first study to focus on RMT as an intervention for emotion regulation in order to evaluate the effects of rap on the self-regulative capacities of adolescents, in support of their well-being. This study protocol aims to outline the method and procedures involved, and to increase attention and awareness of the potential for collaborations involving music, therapy and education for future investigations.
Does the Presence of Very Young Children and/or Older Minor-aged Children in the Home Reduce Cigarette Smoking? Panel Data Evidence for the United States
Authors: Cebula Richard J. , Rossi Fabrizio 
Published: November 2015

Within the context of the Period Fixed-Effects Model, this study of cigarette consumption in the US uses a state-level panel dataset to investigate a new hypothesis. This hypothesis argues that the presence in the home of minor-aged children, that is, children under 18 years of age, reduces the percentage of the population that smokes cigarettes. The eclectic model includes the levels of federal plus state cigarette excise taxation along with a number of other established explanatory variables. The empirical estimates in this preliminary study find support for the hypothesis proffered here, that is, it is found that the percentage of the population that smokes cigarettes is a decreasing function of the percentage of households with minor-aged children residing in the home. Moreover, aside from providing further insight into smoker behaviour, the results from this study also raise the question that since this phenomenon has been ignored in previous related studies involving such public policies as cigarette taxation and cigarette smoking bans that those studies may suffer from omitted variable bias. JEL Classification: R22, I18, H71, H29
Effectiveness of physical and occupational therapy on pain, function and quality of life in patients with trapeziometacarpal osteoarthritis – A systematic review and meta-analysis
Authors: Aebischer Bernhard , Elsig Simone , Taeymans Jan 
Published: November 2015

Introduction Trapeziometacarpal osteoarthritis is associated with more pain and restrictions than other hand osteoarthritis due to the functional importance of the thumb. While the effectiveness of surgical and pharmacological interventions has been widely examined, there is a lack of specific evidence about conservative non-pharmacological trapeziometacarpal osteoarthritis therapies. The objective of this systematic review was to provide evidence-based knowledge on the effectiveness of physiotherapy and occupational therapy on pain, function and quality of life. Methods A literature search of Medline, CINAHL, PEDro, OTseeker, EMB Dare Cochrane Database of Systematic Reviews and Cochrane CENTRAL was performed. Randomized and quasi-randomized controlled trials and corresponding systematic reviews, observational studies, pragmatic studies and case–control studies were included. The risk of bias was assessed. Results Out of 218 studies, 27 were retained. A narrative summary and a series of meta-analyses were performed. Concerning pain reduction, the meta-analysis showed parity of pre-fabricated neoprene and custom-made thermoplastic splints: standardized mean difference (SMD) –0.01 (95%CI −0.43, 0.40) (p=0.95). Multimodal interventions are more effective on pain compared to single interventions: standardized mean difference −3.16 (95%CI −5.56, −0.75) ( p = 0.01). Discussion Physical and occupational therapy-related interventions, especially multimodal interventions, seem to be effective to treat pain in patients with trapeziometacarpal osteoarthritis. Pre-fabricated neoprene splints and custom-made thermoplastic splints may reduce pain equally. Single interventions seem not to be effective. Significant evidence for effectiveness on function and quality of life could not be found.
What explains small- and medium-sized apparel retailers’ international market involvement? An application of Uppsala model
Authors: Cho Hyeon Jeong , Jin Byoungho 
Published: November 2015

AbstractThe purpose of this study is to investigate U.S. small- and medium-sized apparel retailers’ international expansion by proposing a theoretical framework that incorporates the antecedents of small- and medium-sized apparel retail firms’ international market involvement. Data were collected via a self-administered questionnaire completed by apparel retailers nationwide. A total of 76 usable questionnaires were collected based on Dillman et al. (Internet, mail, and mixed-mode surveys: The tailored design method, 2009) Mail Survey technique. The results indicate that small- and medium-sized apparel retailers who have more foreign networks are likely to have foreign market knowledge. Firm age and market knowledge were found to influence a firm’s international market involvement. The results further reveal that market knowledge mediates the relationship between foreign networking and international market involvement. This study contributes to the growing knowledge base about small- and medium-sized retailers’ international expansion in the apparel industry.
Substance misuse in life and death in a 2-year cohort of
suicides
Authors: Galway Karen , Gossrau-Breen Diana , Mallon Sharon , Hughes Lynette , Rosato Michael , Rondon-Sulbaran Janeet , Leavey Gerard 
Published: November 2015

BackgroundAlthough substance misuse is a key risk factor in suicide, relatively
little is known about the relationship between lifetime misuse and misuse
at the time of suicide.AimsTo examine the relationship between substance misuse and subsequent
suicide.MethodLinkage of coroners' reports to primary care records for 403 suicides
occurring over 2 years.ResultsWith alcohol misuse, 67% of the cohort had previously sought help for
alcohol problems and 39% were intoxicated at the time of suicide.
Regarding misuse of other substances, 54% of the cohort was tested.
Almost one in four (38%) tested positive, defined as an excess of drugs
over the prescribed therapeutic dosage and/or detection of illicit
substances. Those tested were more likely to be young and have a history
of drug misuse.ConclusionsA deeper understanding of the relationship between substance misuse and
suicide could contribute to prevention initiatives. Furthermore,
standardised toxicology screening processes would avoid diminishing the
importance of psychosocial factors involved in suicide as a ‘cause of
death’.
Specificity proteins 1 and 4, hippocampal volume and first-episode psychosis
Authors: Fusté Montserrat , Meléndez-Pérez Iria , Villalta-Gil Victoria , Pinacho Raquel , Villalmanzo Núria , Cardoner Narcís , Menchón José M. , Haro Josep Maria , Soriano-Mas Carles , Ramos Belén 
Published: November 2015

SummaryWe assessed specificity protein 1 (SP1) and 4 (SP4) transcription factor levels in peripheral blood mononuclear cells and conducted a voxel-based morphometry analysis on brain structural magnetic resonance images from 11 patients with first-episode psychosis and 14 healthy controls. We found lower SP1 and SP4 levels in patients, which correlated positively with right hippocampal volume. These results extend previous evidence showing that such transcription factors may constitute a molecular pathway to the development of psychosis.
Skill-sharing between allied health professionals in a community setting: A randomised controlled trial
Authors: Pighills Alison C , Bradford Michelle , Bell Kirsty , Flynn Laura J , Williams Gary , Hornsby Danielle , Torgerson David J , Kaltner Melissa 
Published: November 2015

Background/Aims: The increasing demand for health services necessitates workforce redesign to reduce inefficiencies while maintaining quality of care. Health services have been implementing professional skill-sharing models of care to enable allied health practitioners to expand their scope of practice. This article reports the outcome of a randomised controlled trial that investigated the clinical effectiveness of professional skill-sharing. Methods: The Calderdale Framework was used to establish a model of professional skill-sharing. A randomised controlled trial was carried out with community-dwelling older people aged 65 years and above experiencing functional decline (n=153). Participants were randomised to professional skill-sharing intervention (n=77) or uni-professional occupational therapy and/or physiotherapy care control (n=76). Disability, mobility, independence in activities of daily living and quality of life were measured by a blinded assessor at baseline, 1 and 4 months post-randomisation. Results: There were no statistically significant differences in any of the outcome measures between groups. Less than half (43%) of the controls received uni-professional intervention. Sub-group analysis of intervention and control participants who had received uni-professional intervention upheld the results of the main analysis. Conclusions: Professional skill-sharing was equivalent in outcome to conventional, uni-professional occupational therapy and/or physiotherapy for a community-dwelling ageing population experiencing functional decline. Further research is required.
Modelling of Underground Coal Gasification Process Using CFD Methods / Modelowanie Procesu Podziemnego Zgazowania Węgla Kamiennego Z Zastosowaniem Metod CFD
Authors: Wachowicz Jan , Łączny Jacek Marian , Iwaszenko Sebastian , Janoszek Tomasz , Cempa-Balewicz Magdalena 
Published: November 2015

Abstract
The results of model studies involving numerical simulation of underground coal gasification process are presented. For the purpose of the study, the software of computational fluid dynamics (CFD) was selected for simulation of underground coal gasification. Based on the review of the literature, it was decided that ANSYS-Fluent will be used as software for the performance of model studies. The ANSYS- -Fluent software was used for numerical calculations in order to identify the distribution of changes in the concentration of syngas components as a function of duration of coal gasification process. The nature of the calculations was predictive.
A geometric model has been developed based on construction data of the georeactor used during the researches in Experimental Mine “Barbara” and Coal Mine “Wieczorek” and it was prepared by generating a numerical grid. Data concerning the georeactor power supply method and the parameters maintained during the process used to define the numerical model. Some part of data was supplemented based on the literature sources.
The main assumption was to base the simulation of the georeactor operation on a mathematical models describing reactive fluid flow. Components of the process gas and the gasification agent move along the gasification channel and simulate physicochemical phenomena associated with the transfer of mass and energy as well as chemical reactions (together with the energy effect). Chemical reactions of the gasification process are based on a kinetic equation which determines the course of a particular type of equation of chemical coal gasification. The interaction of gas with the surrounding coal layer has also been described as a part of the model. The description concerned the transport of thermal energy. The coal seam and the mass rock are treated as a homogeneous body.
Modelling studies assumed the coal gasification process is carried out with the participation of separately oxygen and air as a gasification agent, under the specific conditions of the georeactor operations within the time interval of 100 hours and 305 hours. The results of the numerical solution have been compared with the results of experimental results under in-situ conditions.
Thermal Power Of The TS-300B Refrigerator in the Aspects of Statistical Research / Moc Cieplna Chłodziarki TS-300B W Aspekcie Badań Statystycznych
Authors: Nowak Bernard , Łuczak Rafał 
Published: November 2015

Abstract
The article discusses the improvement of thermal working conditions in underground mine workings, using local refrigeration systems. It considers the efficiency of air cooling with direct action air compression refrigerator of the TS-300B type. As a result of a failure to meet the required operating conditions of the aforementioned air cooling system, frequently there are discrepancies between the predicted (and thus the expected) effects of its work and the reality. Therefore, to improve the operating efficiency of this system, in terms of effective use of the evaporator cooling capacity, quality criteria were developed, which are easy in practical application. They were obtained in the form of statistical models, describing the effect of independent variables, i.e. the parameters of the inlet air to the evaporator (temperature, humidity and volumetric flow rate), as well as the parameters of the water cooling the condenser (temperature and volumetric flow rate), on the thermal power of air cooler, treated as the dependent variable. Statistical equations describing the performance of the analyzed air cooling system were determined, based on the linear and nonlinear multiple regression. The obtained functions were modified by changing the values of the coefficients in the case of linear regression, and of the coefficients and exponents in the case of non-linear regression, with the independent variables. As a result, functions were obtained, which were more convenient in practical applications. Using classical statistics methods, the quality of fitting the regression function to the experimental data was evaluated. Also, the values of the evaporator thermal power of the refrigerator, which were obtained on the basis of the measured air parameters, were compared with the calculated ones, by using the obtained regression functions. These statistical models were built on the basis of the results of measurements in different operating conditions of the TS-300B refrigerator, both on the test stand in the manufacturer’s laboratory and in the workings of underground mines. The evaluation of the measurement data distributions, as well as an analysis of the basic descriptive statistics of the mentioned variables were carried out, determining their measures of central tendency, location, dispersion and asymmetry.
Application of Concentration-Number and Concentration-Volume Fractal Models to Recognize Mineralized Zones in North Anomaly Iron Ore Deposit, Central Iran / Zastosowanie Modeli Fraktalnych Typu K-L (Koncentracja-Liczba), Oraz K-O (Koncentracja Objętość) Do Rozpoznawania Stref Występowania Surowców Mineralnych W Regionie Złóż Rud Żelaza North Anomaly, W Środkowym Iranie
Authors: Afzal Peyman , Ghasempour Reza , Mokhtari Ahmad Reza , Haroni Hooshang Asadi 
Published: November 2015

Abstract
Identification of various mineralized zones in an ore deposit is essential for mine planning and design. This study aims to distinguish the different mineralized zones and the wall rock in the Central block of North Anomaly iron ore deposit situated in Bafq (Central Iran) utilizing the concentration-number (C-N) and concentration-volume (C-V) fractal models. The C-N model indicates four mineralized zones described by Fe thresholds of 8%, 21%, and 50%, with zones <8% and >50% Fe representing wall rocks and highly mineralized zone, respectively. The C-V model reveals geochemical zones defined by Fe thresholds of 12%, 21%, 43% and 57%, with zones <12% Fe demonstrating wall rocks. Both the C-N and C-V models show that highly mineralized zones are situated in the central and western parts of the ore deposit. The results of validation of the fractal models with the geological model show that the C-N fractal model of highly mineralized zones is better than the C-V fractal model of highly mineralized zones based on logratio matrix.
Selected Methods of Rock Structure Disintegration to Control Mining Hazards / Wybrane Metody Dezintegracji Struktury Skał Dla Zwalczania Zagrożeń Górniczych
Authors: Kabiesz Józef , Lurka Adam , Drzewiecki Jan 
Published: November 2015

Abstract
Natural hazards are inseparable element of underground mining, particularly of coal mining process. They are combated on a regular basis by many measures and effectiveness of these measures determines work safety in mines. Attempts to improve the effectiveness, presented in the paper is based on interference of seismic waves generated by blasting in a selected area of the rock mass and on modification of blasting technology. Preliminary results of detonating classical and new type of explosives in specific temperature and pressure conditions are analyzed. Theoretical and practical consideration of obtaining an interference effect of seismic waves is discussed. A device for making systems of starting notches and a construction of a chamber to test explosives are presented.
1H NMR-based metabolic profiling for evaluating poppy seed rancidity and brewing
Authors: Jawień Ewa , Ząbek Adam , Deja Stanisław , Łukaszewicz Marcin , Młynarz Piotr 
Published: November 2015

AbstractPoppy seeds are widely used in household and commercial confectionery. The aim of this study was to demonstrate the application of metabolic profiling for industrial monitoring of the molecular changes which occur during minced poppy seed rancidity and brewing processes performed on raw seeds. Both forms of poppy seeds were obtained from a confectionery company. Proton nuclear magnetic resonance (The obtained results provide valuable and comprehensive information to gain a better understanding of the biology of rancidity and brewing processes, while demonstrating the potential for applying NMR spectroscopy combined with multivariate data analysis tools for quality control in food industries involved in the processing of oilseeds. This precious and versatile information gives a better understanding of the biology of these processes.
How to take advantage of tablet computers: Effects of news structure on recall and comprehension
Authors: Van Cauwenberge Anna , d’Haenens Leen , Beentjes Hans 
Published: November 2015

AbstractIn light of the growing use of tablets for news reading and mobile news consumption behaviors, this study examined whether an innovative way of structuring news on the tablet that mimics mobile news behaviors reinforced attention for, and learning from, news. Specifically, it was theorized that the chronological and associative structuring of news articles into so-called developing news stories would lead to more attention for news, and better recall and comprehension of news, than the linear print newspaper structure that newspaper publishers continue to copy from print to tablet. A multiple-day experiment was set up using the eye-tracking method to measure and control for attention. The results show that the developing news structure increased comprehension of news substantively, independently of attention effects; no effects were found on attention and factual recall.