bluuebunny/crossref_metadata_2025_split huggingface dataset:
Healthy Behavior Change and Cardiovascular Outcomes in Newly Diagnosed Type 2 Diabetic Patients: A Cohort Analysis of the ADDITION-Cambridge Study
Authors: Long Gráinne H. , Cooper Andrew J.M. , Wareham Nicholas J. , Griffin Simon J. , Simmons Rebecca K. 
Published: March 2014

OBJECTIVE
To examine whether improvements in health behaviors are associated with reduced risk of cardiovascular disease (CVD) in individuals with newly diagnosed type 2 diabetes.

RESEARCH DESIGN AND METHODS
Population-based prospective cohort study of 867 newly diagnosed diabetic patients aged between 40 and 69 years from the treatment phase of the ADDITION-Cambridge study. Because the results for all analyses were similar by trial arm, data were pooled, and results were presented for the whole cohort. Participants were identified via population-based stepwise screening between 2002 and 2006, and underwent assessment of physical activity (European Prospective Investigation into Cancer-Norfolk Physical Activity Questionnaire), diet (plasma vitamin C and self-report), and alcohol consumption (self-report) at baseline and 1 year. A composite primary CVD outcome was examined, comprised of cardiovascular mortality, nonfatal myocardial infarction, nonfatal stroke, and revascularization.

RESULTS
After a median (interquartile range) follow-up period of 5.0 years (1.3 years), 6% of the cohort experienced a CVD event (12.2 per 1,000 person-years; 95% CI 9.3–15.9). CVD risk was inversely related to the number of positive health behaviors changed in the year after diabetes diagnosis. The relative risk for primary CVD event in individuals who did not change any health behavior compared with those who adopted three/four healthy behaviors was 4.17 (95% CI 1.02–17.09), adjusting for age, sex, study group, social class, occupation, and prescription of cardioprotective medication (P for trend = 0.005).

CONCLUSIONS
CVD risk was inversely associated with the number of healthy behavior changes adopted in the year after the diagnosis of diabetes. Interventions that promote early achievement of these goals in patients with newly diagnosed diabetes could help reduce the burden of diabetes-related morbidity and mortality.
Christmas in the 1960s:A Charlie Brown Christmas, Religion, and the Conventions of the Television Genre
Authors: Lind Stephen J. 
Published: March 2014

Abstract:This study of Christmas television programming from the 1960s is prompted by the repeated assertion that A Charlie Brown Christmas was an aberration within the television medium because its creator, Charles Schulz, dared to include religious content in the mainstream title. Grounded by historical/archival research, this article presents a content analysis of Christmas titles from the 1960s formative decade-of-change in order to substantiate the claim of television’s secularity. The findings demonstrate that even in the genre of Christmas programming, mainstream television has abided by a public/private split from this early era, embracing a model of secularity that resists references to religious belief. A Charlie Brown Christmas and its contemporaries are also analyzed to determine the conventions of the genre that may at times afford such religious aberration when otherwise followed.
“Goodbye God, I’m Going to Texas”: The Migration of Louisiana Creoles of Colour and the Preservation of Black Catholic and Creole Traditions in Southeast Texas
Authors: Chambers Glenn 
Published: March 2014

Abstract:This article examines the migration of French-speaking blacks and Creoles of Colour from Southern Louisiana to Texas during the first half of the twentieth century. It centers on the importance of Catholic churches as cultural centers for the preservation of Creole culture beyond Louisiana’s borders and shows how religious orders attempted to preserve the faith of migrant black Catholics by insulating them from many aspects of racial inequality and segregation in its religious environment. The Church helped Creole communities maintain their ethnic and cultural ties to Louisiana. However, the resulting cultural exclusivity of a Catholic and Creole identity alienated the broader African American community.
The Marvel of Islam: Reconciling Muslim Epistemologies through a New Islamic Origin Saga in Naif al-Mutawa’s The 99
Authors: Clements James , Gauvain Richard 
Published: March 2014

Abstract: Since its inception in 2006, Islam’s most popular comic strip, The 99, and its creator, Naif al-Mutawa, have both been the subject of much media scrutiny. Despite eschewing references to the most significant texts, figures, and symbols of Islam—readers of the comic find no mention of the Qur’an or the Prophet—neither its fiercest critics nor its most fervent supporters doubt the essentially Islamic nature of The 99. Drawing on the responses of students at the American University in Dubai (AUD), this paper explores how and why, within this modern Gulf setting, The 99 resonates as a profoundly Islamic publication. Attention is paid, first, to The 99’s origin saga, through which Muslim history is smoothed over, then re-spun in ways familiar to our students; and, second, to a number of special editions of The 99, through which al-Mutawa offers a new understanding of Islam’s role—with remarkable implications for political leadership—in contemporary society, both Muslim and non-Muslim.
The Islamic Framing in Donald Moffitt’s Science Fiction SeriesThe Mechanical Sky
Authors: Olsson Susanne 
Published: March 2014

Abstract:American author Donald Moffitt’s science fiction (SF) series The Mechanical Sky, consisting of two books, Crescent in the Sky (1989) and A Gathering of Stars (1990), portrays a universe where various religious denominations exist, and where an Islamic caliphate is established, aiming at universal Islamic dominance. The purpose of this article is to analyze the series pertaining to its representations of Islam and Muslims, and to explain the Islamic framing in contextualizing the series in the historical situation when the series was produced. Moreover, another aim of the article concerns the methodological problems that such an analysis of the Islamic framing may entail. The article calls for the need to reflect seriously on interpretative perspectives when a scholar in the study of religions enters the field of SF, which has its own definitional problems and genre-specific traits that must be taken into consideration.
Axl Receptor Blockade Ameliorates Pulmonary Pathology Resulting from Primary Viral Infection and Viral Exacerbation of Asthma
Authors: Shibata Takehiko , Habiel David M. , Coelho Ana L. , Kunkel Steven L. , Lukacs Nicholas W. , Hogaboam Cory M. 
Published: March 2014

Abstract
Viruses use Tyro3, Axl, and Mertk (TAM) receptor tyrosine kinases to infect and modulate the immune properties of various cell types, which led us to investigate whether TAM receptor activation affected primary viral infection and viral exacerbation of asthma in experimental models. In these lung-specific models, we observed that Axl was the most abundantly induced TAM receptor protein. During primary respiratory syncytial virus (RSV) infection, anti-Axl mAb treatment significantly increased the number of IFN-γ–producing T cells and NK cells and significantly suppressed RSV replication and whole lung levels of IL-4 and IL-13. Intrapulmonary H1N1 infection induced lethal pulmonary inflammation, but anti-Axl mAb treatment of infected mice significantly increased the number of IFN-β–producing macrophages and dendritic cells and significantly suppressed neutrophil infiltration. Consequently, the lethal effect of H1N1 infection in this model was significantly reduced in the mAb-treated group compared with the IgG control-treated group. Targeting Axl also inhibited airway hyperresponsiveness, IL-4 and IL-13 production, and goblet cell metaplasia in an Aspergillus fumigatus–induced asthma model. Finally, infection of mice with RSV during fungal asthma significantly exacerbated airway inflammation, goblet cell metaplasia, and airway remodeling, but all of these features in this viral exacerbation model were ameliorated by anti-Axl mAb treatment. Taken together, these results demonstrate that Axl modulates the pulmonary immune response during viral and/or allergic pathology, and they also suggest that targeting this TAM receptor might provide a novel therapeutic approach in these infectious diseases.
Integrin α4β1 Is Necessary for CD4+ T Cell–Mediated Protection against Genital Chlamydia trachomatis Infection
Authors: Davila Sergio J. , Olive Andrew J. , Starnbach Michael N. 
Published: March 2014

Abstract
Chlamydia trachomatis infection is the most common sexually transmitted bacterial infection in the United States and a significant health burden worldwide. Protection from Chlamydia infection in the genital mucosa is dependent on IFN-γ derived from CD4+ Th1 cells. These CD4+ T cells must home successfully to the genital tract to exert their effector function and decrease C. trachomatis burden. Although adhesion receptors expressed by CD4+ T cells in the genital tract have been characterized, the integrin receptor required for Chlamydia-specific CD4+ T cell–mediated protection has not been explored. In this study, we demonstrate that C. trachomatis infection of the upper genital tract results in recruitment of Chlamydia-specific CD4+ T cells robustly expressing the integrin α4β1. Interfering with α4β1, but not α4β7, function resulted in defective CD4+ T cell trafficking to the uterus and high bacterial load. We conclude that integrin α4β1 is necessary for CD4+ T cell–mediated protection against C. trachomatis infection in the genital mucosa. By identifying homing molecules required for successful CD4+ T cell trafficking to C. trachomatis–infected tissues, we will be better equipped to design vaccines that elicit sterilizing, long-lasting immunity without inducing immune pathologies in the upper genital tract.
Do Occupational Therapy Graduates Benefit from Grade Inflation on Practice Placements?
Authors: Roden Paul 
Published: March 2014

Introduction: Graduate records from Brunel University (United Kingdom) occupational therapy student cohorts from 1995–2005 were examined to discover the impact of practice placement marking on overall academic performance. Numeric grades for practice placements were introduced in 2000; prior to that, practice placement marks were recorded as either pass or fail. Method: 1057 records were examined to compare whether overall academic averages differed between pre-practice marking and post-practice marking. Findings: Significant differences were discovered in the academic averages for 1995–99 (pass/fail) cohorts and 2000–04 (placement marking) cohorts. Further evaluation of the 2000–04 cohorts' marks (n = 593) revealed that practice placement marks contributed to that increase, and showed a significant rising trend when considered separately from marks from academic modules. Conclusion: An upward trend in practice placement marking can be seen, year on year, which indicates that grade inflation is present in practice placement marking.
Evaluation of Participation in Occupations of Older Adults Receiving Home-Based Services
Authors: Vik Kjersti , Eide Arne Henning 
Published: March 2014

Introduction: The aim of this article was to study aspects of the evaluation of participation in occupations of older adults with beginning functional decline who receive home-based services. The aspects of evaluation studied were importance of, satisfaction with, and choice in participation. Method: A cross-sectional interview-based survey of 155 older adults receiving home-based services, administered through the Participation Survey/Mobility. The data were analysed with descriptive statistics. Findings: Moving around in the house, being in charge of personal care, and participating in leisure activities were perceived as the most important occupations for participation. Respondents were most satisfied with their participation in managing money, and least satisfied with their participation in leisure and social activities. Participation in leisure activities afforded them more choice than participation in physical activities. Few significant differences were found between gender, age, and level of functioning. Conclusion: In general, participation in both personal care and leisure activities was perceived as important, and the respondents felt they had choice when performing these occupations. They were less satisfied with their participation in social occupations, supporting the need for occupational therapists to enhance participation in this area.
Burnout and Work Engagement in Occupational Therapists
Authors: Poulsen Anne A , Meredith Pamela , Khan Asaduzzaman , Henderson Julie , Castrisos Veronica , Khan Shanchita R 
Published: March 2014

Introduction: Work engagement, characterized by vigour, dedication, and absorption, is often perceived as the opposite of burnout. Occupational therapists with burnout feel exhausted and disengaged from their work. This study aims to investigate demographic and work-related psychosocial factors associated with burnout and work engagement. Method: A cross-sectional postal survey of 951 occupational therapists was conducted. Findings: Two models representing factors associated with burnout (F(15,871) = 28.01, p < .001) and work engagement (F(10,852) = 16.15, p < .001) accounted for 32.54% and 15.93% of the variance respectively. Burnout and work engagement were inversely associated (χ2(n = 941) = 55.16, p < .001). Conclusion: Factors associated with burnout and work engagement were identified. The variables associated with burnout included: low psychological detachment from work during out-of-work hours, low income satisfaction, perceived work overload, difficulty saying ‘no’, < 10 years' experience, low frequency of having a ‘belly laugh’, and not having children. High levels of work engagement were reported by therapists with the following: low psychological detachment from work, high income satisfaction, postgraduate qualifications, > 40 hours work/week, high frequency of having a ‘belly laugh’, and having children. Understanding the factors associated with burnout and work engagement provides prerequisite information to inform strategies aimed at building healthy workforces.
Modeling maximum daily temperature using a varying coefficient regression model
Authors: Li Han , Deng Xinwei , Kim Dong‐Yun , Smith Eric P. 
Published: March 2014

AbstractRelationships between stream water and air temperatures are often modeled using linear or nonlinear regression methods. Despite a strong relationship between water and air temperatures and a variety of models that are effective for data summarized on a weekly basis, such models did not yield consistently good predictions for summaries such as daily maximum temperature. A good predictive model for daily maximum temperature is required because daily maximum temperature is an important measure for predicting survival of temperature sensitive fish. To appropriately model the strong relationship between water and air temperatures at a daily time step, it is important to incorporate information related to the time of the year into the modeling. In this work, a time‐varying coefficient model is used to study the relationship between air temperature and water temperature. The time‐varying coefficient model enables dynamic modeling of the relationship, and can be used to understand how the air‐water temperature relationship varies over time. The proposed model is applied to 10 streams in Maryland, West Virginia, Virginia, North Carolina, and Georgia using daily maximum temperatures. It provides a better fit and better predictions than those produced by a simple linear regression model or a nonlinear logistic model.
Interfacial polymerization of poly(2,5‐dimethoxyaniline) and its enhanced capacitive performances
Authors: Xiong Shanxin , Shi Yujing , Chen Shi , Li Jie , Wang Xiaoqin , Chu Jia , Gong Ming , Wu Bohua 
Published: March 2014

ABSTRACTThe poly(2,5‐dimethoxyaniline) (PDMA) were synthesized through interfacial polymerization method using three various organic solvent/water reaction systems. As comparison with conventional chemical polymerized PDMA, the interfacial polymerization can produce uniform nanoparticular PDMA, especially for using high density (higher than water) solvent as organic phase. The capacitive performances of interfacial polymerized PDMA can be benefited from its uniform morphologies and loose packing structure. The specific capacitance of interfacial polymerized PDMA using carbon tetrachloride is 194 Fg−1 at current density of 50 mA cm−2, which has 59% enhancement over 122 Fg−1 of conventional PDMA at the same current density. The energy density of interfacial polymerized PDMA is 39 Wh kg−1 at current density of 5 mA cm−2 and the power density is 28,421 W kg−1 at current density of 50 mA cm−2. The energy density has improvement in different extent as comparison with that of conventional PDMA. The enhanced capacitive performances can be attributed to the increased ionic conductivity induced by the loose molecular packing structure and uniform morphology produced by the interfacial polymerization process. © 2014 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2014, 131, 40666.
Are there common familial influences for major depressive disorder and an overeating–binge eating dimension in both European American and African American Female twins?
Authors: Munn‐Chernoff Melissa A. , Grant Julia D. , Agrawal Arpana , Koren Rachel , Glowinski Anne L. , Bucholz Kathleen K. , Madden Pamela A.F. , Heath Andrew C. , Duncan Alexis E. 
Published: March 2014

ABSTRACTObjectiveAlthough prior studies have demonstrated that depression is associated with an overeating–binge eating dimension (OE‐BE) phenotypically, little research has investigated whether familial factors contribute to the co‐occurrence of these phenotypes, especially in community samples with multiple racial/ethnic groups. We examined the extent to which familial (i.e., genetic and shared environmental) influences overlapped between Major Depressive Disorder (MDD) and OE‐BE in a population‐based sample and whether these influences were similar across racial/ethnic groups.MethodParticipants included 3,226 European American (EA) and 550 African American (AA) young adult women from the Missouri Adolescent Female Twin Study. An adaptation of the Semi‐Structured Assessment for the Genetics of Alcoholism (SSAGA) was administered to assess lifetime DSM‐IV MDD and OE‐BE. Quantitative genetic modeling was used to estimate familial influences between both phenotypes; all models controlled for age.ResultsThe best‐fitting model, which combined racial/ethnic groups, found that additive genetic influences accounted for 44% (95% CI: 34%, 53%) of the MDD variance and 40% (25%, 54%) for OE‐BE, with the remaining variances due to non‐shared environmental influences. Genetic overlap was substantial (rg = .61 [.39, .85]); non‐shared environmental influences on MDD and OE‐BE overlapped weakly (re = .26 [.09, .42]).DiscussionResults suggest that common familial influences underlie MDD and OE‐BE, and the magnitude of familial influences contributing to the comorbidity between MDD and OE‐BE is similar between EA and AA women. If racial/ethnic differences truly exist, then larger sample sizes may be needed to fully elucidate familial risk for comorbid MDD and OE‐BE across these groups. © 2014 Wiley Periodicals, Inc. (Int J Eat Disord 2015; 48:375–382)
Capillary electrokinetic fractionation mass spectrometry (CEkF/MS): Technology setup and application to metabolite fractionation from complex samples coupled at‐line with ultrahigh‐resolution mass spectrometry
Authors: He Yu , Harir Mourad , Chen Guonan , Gougeon Regis D. , zhang Lan , Huang Xiayang , Schmitt‐Kopplin Philippe 
Published: March 2014

Capillary electrokinetic fractionation (CEkF) is investigated as a new, simple, and robust approach for semipreparative and analytical sample analysis based on pKa‐dependant pH‐driven electrophoretic mobility. CEkF was optimized with contactless conductivity detection and conducted with 10 kV reverse voltage for 10 min, then coupled on/at‐line to ESI/MS. We propose a semi‐empirical model with 14 representative compounds based on the correlation between sample/medium pH regulating the partial charge, the electrokinetic loading of the capillary and intensity (I) of analytes. According to the model, an empirical function (I = f (pH)) could be derived to calculate the acid dissociation constant (pKa) of various model compounds based on their pH‐dependant MS intensity profiles with the RSD < 4.05. Using the ultrahigh‐resolution of ion cyclotron resonance Fourier transform MS, the pKa model was further illustrated in real samples into the structure prediction of important compounds in wine over two vintages. The established CEkF was successfully used to selectively fractionate sulfur compounds from the complex wine samples at pH 1.66. The proposed CEkF approach should allow in the future the simultaneous pKa evaluation of multiple constituents without complicated separation out of a complex mixture in metabolomics or environmental chemistry.
Construction of an Immunochromatographic Determination System for N1,N12‐diacetylspermine
Authors: Moriya Shun‐suke , Hiramatsu Kyoko , Kimura Emi , Matsumoto Kyoichi , Kawakita Masao 
Published: March 2014

BackgroundN1,N12‐diacetylspermine (DiAcSpm) is a recently identified tumor marker. Its concentration increases in the urine of cancer patients at early clinical stages. To utilize this characteristic feature and thus contribute to the early detection of cancer, we developed an immunochromatographic determination system for DiAcSpm.MethodsWe examined the factors that affect the performance and stability of our determination system, including antibody selection and the conditions for the formation of stably dispersed antibody‐coated gold nanoparticles. We then tested the performance of the system by determining the DiAcSpm concentration in human urine samples.ResultsWe constructed an immunochromatographic strip using anti‐DiAcSpm antibody‐coated gold nanoparticles in the conjugate pad and an acetylspermine–protein conjugate (a DiAcSpm mimic) immobilized on the analyzing membrane. The use of the immunochromatographic strip and an immunochromato‐reader allowed for the quantitative determination of DiAcSpm in the range of 20 to 700 nM. The analytical values obtained by this method were well correlated with those determined by a colloidal gold aggregation procedure using an automatic biochemical analyzer. The immunochromatographic strip was stable for at least 8 weeks at 50°C.ConclusionsA competitive immunochromatographic device for DiAcSpm determination was developed in this study. This simple device will contribute to increasing the opportunities for early cancer detection and timely care.