bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of feeding buckwheat and chicory silages on fatty acid profile and cheese-making properties of milk from dairy cows
Authors: Kälber Tasja , Kreuzer Michael , Leiber Florian 
Published: December 2012

Fresh buckwheat (Fagopyrum esculentum) and chicory (Cichorium intybus) had been shown to have the potential to improve certain milk quality traits when fed as forages to dairy cows. However, the process of ensiling might alter these properties. In the present study, two silages, prepared from mixtures of buckwheat or chicory and ryegrass, were compared with pure ryegrass silage (Lolium multiflorum) by feeding to 3 × 6 late-lactating cows. The dietary dry matter proportions realised for buckwheat and chicory were 0·46 and 0·34 accounting also for 2 kg/d of concentrate. Data and samples were collected from days 10 to 15 of treatment feeding. Buckwheat silage was richest in condensed tannins. Proportions of polyunsaturated fatty acids (PUFA) and α-linoleic acid in total fatty acids (FA) were highest in the ryegrass silage. Feed intake, milk yield and milk gross composition did not differ among the groups. Feeding buckwheat resulted in the highest milk fat concentrations (g/kg) of linoleic acid (15·7) and total PUFA (40·5; bothP < 0·05 compared with ryegrass). The concentration of α-linolenic acid in milk fat was similar across treatments, but its apparent recovery in milk relative to the amounts ingested was highest with buckwheat. The same was true for the occurrence of FA biohydrogenation products in milk relative to α-linolenic acid intake. Recovery of dietary linoleic acid in milk remained unaffected. Feeding buckwheat silage shortened rennet coagulation time by 26% and tended (P < 0·1) to increase curd firmness by 29%. In conclusion, particularly buckwheat silage seems to have a certain potential to modify the transfer of FA from feed to milk and to contribute to improved cheese-making properties.
Activation of hatching in diapaused and quiescentGlobodera pallida
Authors: PALOMARES-RIUS JUAN E. , JONES JOHN T. , COCK PETER J. , CASTILLO PABLO , BLOK VIVIAN C. 
Published: December 2012

SUMMARYThe potato cyst nematodes (PCN)Globodera pallidaandG. rostochiensisare major pests of potatoes. TheG. pallida(andG. rostochiensis) life cycle includes both diapause and quiescent stages. Nematodes in dormancy (diapause or quiescent) are adapted for long-term survival and are more resistant to nematicides. This study analysed the mechanisms underlying diapause and quiescence. The effects of several compounds (8Br-cGMP, oxotremorine and atropine) on the activation of hatching were studied. The measurements of some morphometric parameters in diapaused and quiescent eggs after exposure to PRD revealed differences in dorsal gland length, subventral gland length and dorsal gland nucleolus. In addition, the expression of 2 effectors (IVg9 and cellulase) was not induced in diapaused eggs in water or PRD, while expression was slightly induced in quiescent eggs. Finally, we performed a comparative study to identify orthologues ofC. elegansdiapause related genes in plant-parasitic nematodes (G. pallida, Meloidogyne incognita, M. haplaandBursaphelenchus xylophilus). This analysis suggested that it was not possible to identifyG. pallidaorthologues of the majority ofC. elegansgenes involved in the control of dauer formation. All these data suggest thatG. pallidamay use different mechanisms toC. elegansin regulating the survival stage.
Reproductive consequences of host age in a desert flea
Authors: LIBERMAN VICTORIA , KHOKHLOVA IRINA S. , DEGEN A. ALLAN , KRASNOV BORIS R. 
Published: December 2012

SUMMARYWe tested for the effect of age of a rodent host (Meriones crassus) on reproductive performance of fleas in terms of number and quality of offspring and predicted that fleas would perform better on juvenile and old than on subadult and adult hosts. The number of flea offspring was evaluated via egg and new imago production, while their quality was estimated via duration of development, resistance to starvation and body size. Although fleas produced more eggs when they exploited adults than when they exploited juvenile, subadult and old hosts, significantly more new imago emerged from fleas fed on juvenile and old hosts than on subadult and adult hosts. Fleas performed better when they fed on juvenile and/or old hosts than on subadult and adult hosts in 2 of 3 measures of offspring quality (duration of development and body size). Nevertheless, when offspring quality was estimated via resistance to starvation of a new imago, fleas demonstrated good performance in young (juvenile and subadult) hosts, while they performed poorly in old hosts. Thus, general reproductive performance of fleas was better when they exploited young and old hosts than when they exploited median age cohorts. However, the effect of host age on flea reproductive performance was manifested somewhat differently between (a) male and female hosts and (b) male and female flea offspring.
The Reliability of Trends over Time in International Education Test Scores: Is the Performance of England's Secondary School Pupils Really in Relative Decline?
Authors: JERRIM JOHN 
Published: December 2012

AbstractThe Programme for International Student Assessment (PISA) and Trends in International Mathematics and Science Study (TIMSS) are respected cross-national studies of pupil achievement. They have been specifically designed to study how countries’ educational systems are performing against one another, and how this is changing over time. These are, however, politically sensitive issues, where different surveys can produce markedly different results. This is shown via a case study for England, where apparent decline in PISA test performance has caused policymakers much concern. Results suggest that England's drop in the PISA ranking is not replicated in TIMSS, and that this contrast may be due to data limitations in both surveys. Consequently, I argue that the current coalition government should not base educational policies on the assumption that the performance of England's secondary school pupils has declined over the past decade.
Horizontal and vertical target efficiency – a comparison between users and non-users of public long-term care in Sweden
Authors: LAGERGREN MÅRTEN , SJÖLUND BRITT-MARIE , FAGERSTRÖM CECILIA , BERGLUND JOHAN , FRATIGLIONI LAURA , NORDELL EVA , WIMO ANDERS , ELMSTÅHL SÖLVE 
Published: December 2012

ABSTRACTThe extent to which a system of services is in tune with the needs of the population can be expressed in terms of target efficiency, which includes horizontal target efficiency – the extent to which those deemed to need a service receive it – and vertical target efficiency – the corresponding extent to which those who receive a service actually need it. Vertical efficiency can be measured by looking only at those receiving services. To measure horizontal target efficiency in a population, one must have access to population surveys. Data were taken from the baseline survey of the Swedish National Study on Ageing and Care (SNAC study). The results show that more than 80 per cent of those dependent in personal activities of daily living in the studied geographic areas were users of public long-term care (LTC). Dependency in instrumental activities of daily living was identified as the most important predictor of using LTC. Vertical target efficiency was 83–95 per cent depending on age, gender and type of household, if need was defined as dependency in instrumental activities of daily living. It was considerably lower, 35–61 per cent when defined as dependency in personal daily activities. Overall, long-term target efficiency in Sweden must be regarded as high. Few persons who need public LTC services fail to receive them.
‘I was there when she passed’: older widowers' narratives of the death of their wife
Authors: VAN DEN HOONAARD DEBORAH K. , BENNETT KATE MARY , EVANS ELIZABETH 
Published: December 2012

ABSTRACTThere is evidence that older widowed women provide narrative accounts of the events that led up to the deaths of their husbands. These accounts are qualitatively different from other parts of their interviews. This study examines interviews from older widowers and asks what features characterise their narrative accounts of their wife's death. The data show that men do speak of the death of their wife in a qualitatively different way than they do of other matters: women speak emotionally whilst men speak of their behaviour. Using Kirsi, Hervonen and Jylhä's typology of male care-givers, we find that their interviews are characterised by four types of speech: factual, agentic, familistic and destiny speech. In addition, we find two additional speech types related to blame – one related to medical negligence (a subset of destiny speech) and one to self-blame (a subset of familistic speech). We argue that the use of these patterns of speech allow men to preserve their masculine identities at a time when bereavement puts them under intense strain.
Metabolic risk factors in first-episode schizophrenia: baseline prevalence and course analysed from the European First-Episode Schizophrenia Trial
Authors: Fleischhacker W. Wolfgang , Siu Cynthia O. , Bodén Robert , Pappadopulos Elizabeth , Karayal Onur N. , Kahn René S. ,   the EUFEST study group
Published: December 2012

Abstract
Available data on antipsychotic-induced metabolic risks are often constrained by potential confounding effects due to prior antipsychotic treatment. In this study, we assessed the baseline prevalence of metabolic abnormalities and changes following treatment with five commonly-used antipsychotic drugs (haloperidol, amisulpride, olanzapine, quetiapine or ziprasidone) in first-episode, partially antipsychotic-naive patients with schizophrenia in the European first-episode schizophrenia trial (EUFEST). Overall baseline prevalence of metabolic syndrome (MetS) was 6.0%, with similar rates observed in the antipsychotic-naive patients (5.7%, 9/157) and in the other patients with only a brief prior exposure to antipsychotics (6.1%, 20/326). These results are consistent with the MetS prevalence rate estimated in a general population of similar age. Examination of individual risk factors showed 58.5% of subjects had one or more elevated metabolic risks at baseline: 28.5% demonstrated suboptimal HDL; 24.2% hypertension; 17.7% hypertriglyceridemia; 8.2% abdominal obesity; 7.3% hyperglycaemia. Increase in body weight (kg/month) occurred in patients treated with haloperidol (0.62 s.e. 0.11), amisulpride (0.76 s.e. 0.08), olanzapine (0.98 s.e. 0.07) and quetiapine (0.58 s.e. 0.09), which was significantly greater than that in the ziprasidone group (0.18 s.e. 0.10). The incidence rate of new diabetes cases over a 52-wk follow-up period was 0.82% (4/488). More patients experienced worsening rather than improvement of hypertriglyceridemia or hyperglycaemia in all treatment groups. Our findings suggest that in first-episode, partially antipsychotic-naive patients, the baseline prevalence rate of MetS appears to be no higher than that in the general population, but serious underlying individual risk factors nevertheless existed.
Vaccine development for protecting swine against influenza virus
Authors: Chen Qi , Madson Darin , Miller Cathy L. , Harris D.L. Hank 
Published: December 2012

AbstractInfluenza virus infects a wide variety of species including humans, pigs, horses, sea mammals and birds. Weight loss caused by influenza infection and/or co-infection with other infectious agents results in significant financial loss in swine herds. The emergence of pandemic H1N1 (A/CA/04/2009/H1N1) and H3N2 variant (H3N2v) viruses, which cause disease in both humans and livestock constitutes a concerning public health threat. Influenza virus contains eight single-stranded, negative-sense RNA genome segments. This genetic structure allows the virus to evolve rapidly by antigenic drift and shift. Antigen-specific antibodies induced by current vaccines provide limited cross protection to heterologous challenge. In pigs, this presents a major obstacle for vaccine development. Different strategies are under development to produce vaccines that provide better cross-protection for swine. Moreover, overriding interfering maternal antibodies is another goal for influenza vaccines in order to permit effective immunization of piglets at an early age. Herein, we present a review of influenza virus infection in swine, including a discussion of current vaccine approaches and techniques used for novel vaccine development.
Did Secularism Fail? The Rise of Religion in Turkish Politics
Authors: Taydas Zeynep , Akbaba Yasemin , Morrison Minion K. C. 
Published: December 2012

AbstractReligious movements have long been challenging the modernist and secularist ideas around the world. Within the last decade or so, pro-religious parties made significant electoral advances in various countries, including India, Sudan, Algeria, and the Palestinian territories. In this article, we focus on the rise of the pro-religious Justice and Development Party (Adalet ve Kalkınma Partisi- AKP) to power in the 2002 elections in Turkey. Using the Turkish experience with political Islam, we evaluate the explanatory value of Mark Juergensmeyer's rise of religious nationalism theory, with a special emphasis on the “failed secularism” argument. Our analysis indicates that the theoretical approach formulated by Juergensmeyer has a great deal of explanatory power; however, it does not provide a complete explanation for the success of the AKP. The rise of religion in Turkish politics is the result of a complex process over long years of encounter and confrontation between two frameworks of order, starting with the sudden imposition of secularism from above, when the republic was established. Hence, to understand the rise of religion in contemporary Turkish politics, an in-depth understanding of history, politics, and the sources of tension between secularists and Islamists is essential. The findings of this article have important implications for other countries, especially those that are experiencing a resurgence of religion in politics, and are struggling to integrate religious parties into a democratic system.
Mechanics of Old Faithful Geyser, Calistoga, California
Authors: Rudolph M. L. , Manga M. , Hurwitz S. , Johnston M. , Karlstrom L. , Wang C.‐Y. 
Published: December 2012

In order to probe the subsurface dynamics associated with geyser eruptions, we measured ground deformation at Old Faithful Geyser of Calistoga, CA. We present a physical model in which recharge during the period preceding an eruption is driven by pressure differences relative to the aquifer supplying the geyser. The model predicts that pressure and ground deformation are characterized by an exponential function of time, consistent with our observations. The geyser's conduit is connected to a reservoir at a depth of at least 42 m, and pressure changes in the reservoir can produce the observed ground deformations through either a poroelastic or elastic mechanical model.
Managing biological complexity across orthologs with a visual knowledgebase of documented biomolecular interactions
Authors: VanBuren Vincent , Chen Hailin 
Published: December 2012

AbstractThe complexity of biomolecular interactions and influences is a major obstacle to their comprehension and elucidation. Visualizing knowledge of biomolecular interactions increases comprehension and facilitates the development of new hypotheses. The rapidly changing landscape of high-content experimental results also presents a challenge for the maintenance of comprehensive knowledgebases. Distributing the responsibility for maintenance of a knowledgebase to a community of subject matter experts is an effective strategy for large, complex and rapidly changing knowledgebases. Cognoscente serves these needs by building visualizations for queries of biomolecular interactions on demand, by managing the complexity of those visualizations and by crowdsourcing to promote the incorporation of current knowledge from the literature.
Polyphenols differentially inhibit degranulation of distinct subsets of vesicles in mast cells by specific interaction with granule-type-dependent SNARE complexes
Authors: Yang Yoosoo , Oh Jung-Mi , Heo Paul , Shin Jae Yoon , Kong Byoungjae , Shin Jonghyeok , Lee Ji-Chun , Oh Jeong Su , Park Kye Won , Lee Choong Hwan , Shin Yeon-Kyun , Kweon Dae-Hyuk 
Published: December 2012

Anti-allergic effects of dietary polyphenols were extensively studied in numerous allergic disease models, but the molecular mechanisms of anti-allergic effects by polyphenols remain poorly understood. In the present study, we show that the release of granular cargo molecules, contained in distinct subsets of granules of mast cells, is specifically mediated by two sets of SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) proteins, and that various polyphenols differentially inhibit the formation of those SNARE complexes. Expression analysis of RBL-2H3 cells for 11 SNARE genes and a lipid mixing assay of 24 possible combinations of reconstituted SNAREs indicated that the only two active SNARE complexes involved in mast cell degranulation are Syn (syntaxin) 4/SNAP (23 kDa synaptosome-associated protein)-23/VAMP (vesicle-associated membrane protein) 2 and Syn4/SNAP-23/VAMP8. Various polyphenols selectively or commonly interfered with ternary complex formation of these two SNARE complexes, thereby stopping membrane fusion between granules and plasma membrane. This led to the differential effect of polyphenols on degranulation of three distinct subsets of granules. These results suggest the possibility that formation of a variety of SNARE complexes in numerous cell types is controlled by polyphenols which, in turn, might regulate corresponding membrane trafficking.
The effect of morphological and functional variables on ranking position of professional junior Basque surfers
Authors: Fernández‐López Juan Ramón , Cámara Jesús , Maldonado Sara , Rosique‐Gracia Javier 
Published: December 2012

AbstractThe aim of this study was to analyse the association of morphology as well as functional outcomes during a paddling test with ranking position (RP) of competitive junior surfers. Ten male surfers (age, mean 17.60, s=2.06 years) performed a maximum incremental test on a modified ergometer (Ergo Vasa Swim, USA) to determine, per unit of weight, the relative heart rate at lactate threshold (RHRLT) and at onset of blood lactate accumulation (RHROBLA) and the relative power output at LT (RWLT) and at OBLA (RWOBLA). Anthropometrics were weight, height and sum of six skinfolds (subscapular, triceps, supraspinal, abdominal, anterior thigh and calf) and Heath‐Carter anthropometric somatotypes. A stepwise multiple regression was constructed to model and predict RP. Surfers shared a relative short stature and light weight, with a broader range of skinfold thickness (174.30, s=0.07 cm; 66.73, s=5.91 kg; 57.03, s=12.29 mm) and mean somatotype was ectomorphic‐mesomorph: 2.20–4.36–3.09 (Category 2). Two model equations were possible: (A) RP = − 244.550 RWOBLA+262.787; (B) RP = − 217.028·RWOBLA+31.21·endomorphy + 169.16 with 63.1% and 83% of variance explained, respectively. A hierarchical cluster analysis on the Euclidean distances of the variables in model B also distinguished between upper and lower ranking groups. RWOBLA was more useful than endomorphy, anthropometric measures and also than the other functional outcomes to predict RPs. RWOBLA and endomorphy should be considered important variables that may influence the success of these young competitive surfers.
Knee loading patterns in a simulated netball landing task
Authors: Stuelcken Max , Greene Andrew , Smith Richard , Vanwanseele Benedicte 
Published: December 2012

AbstractThe knee is a common site of injury in netball players. In this study, 10 high‐performance netball players underwent a biomechanical assessment of their single leg landing technique whilst receiving a pass. Three‐dimensional video and ground reaction force data were recorded using a motion analysis system. Net internal knee joint moments were calculated using a rigid body analysis and inverse dynamics. The kinematics of the support leg and front‐on video footage was used to investigate whether players adhered to guidelines on safe and effective landing strategies. Results indicated that for most players the internal valgus moment was the largest frontal plane knee moment during the landing phase. This may reflect a relatively greater need to resist varus knee excursion or may be related to the kinematics of the hip. For 6 of the 10 players the rapid change to an internal knee valgus moment coincided with hip adduction. Since an increase in the magnitude of the internal valgus moment may increase the compressive forces in the medial compartment of the knee, further work should be undertaken to determine if a neuromuscular training intervention to improve the strength of the hip musculature may be beneficial for these players. A large relative excursion of the knee compared to the hip may indicate that these players had a greater reliance on the more distal segments of the lower extremity for the attenuation of the ground reaction forces. This information may be used to better understand potential knee injury mechanisms in netball players.
Unnecessary Antimicrobial Use in Patients with Current or Recent Clostridium difficile Infection
Authors: Shaughnessy Megan K. , Amundson William H. , Kuskowski Michael A. , DeCarolis Douglas D. , Johnson James R. , Drekonja Dimitri M. 
Published: December 2012

Objective.To determine the fraction of unnecessary antimicrobial use among patients with current and/or recent Clostridium difficile infection (CDI).Design.Retrospective review from January 2004 through December 2006.Setting.Minneapolis Veterans Affairs Medical Center (MVAMC).Participants.Patients with new-onset CDI diagnosed at the MVAMC without another CDI diagnosis in the prior 30 days.Methods.Pharmacy and medical records were reviewed to identify incident CDI cases, non-CDI antimicrobial use during and up to 30 days after completion of CDI treatment, and patient characteristics. Two infectious disease physicians independently assessed non-CDI antimicrobial use, which was classified as unnecessary if not fully indicated. Factors associated with only unnecessary use were identified through univariable and multivariable analysis.Results.Of 246 patients with new-onset CDI, 141 (57%) received non-CDI antimicrobials during and/or after their CDI treatment, totaling 2,147 antimicrobial days and 445 antimicrobial courses. The two reviewers agreed regarding the necessity of antimicrobials in more than 99% of antimicrobial courses (85% initially, 14% after discussion). Seventy-seven percent of patients received at least 1 unnecessary antimicrobial dose, 26% of patients received only unnecessary antimicrobials, and 45% of total non-CDI antimicrobial days included unnecessary antimicrobials. The leading indications for unnecessary antimicrobial use were putative urinary tract infection and pneumonia. Drug classes frequently used unnecessarily were fluoroquinolones and β-lactams.Conclusions.Twenty-six percent of patients with recent CDI received only unnecessary (and therefore potentially avoidable) antimicrobials. Heightened awareness and caution are needed when antimicrobial therapy is contemplated for patients with recent CDI.