bluuebunny/crossref_metadata_2025_split huggingface dataset:
Laparoscopic adjustable gastric band survival in a high-volume bariatric unit
Authors: Brown J J S , Boyle M , Mahawar K , Balupuri S , Small P K 
Published: June 2014

Abstract

Background
Although laparoscopic adjustable gastric bands (LAGBs) have been shown to be efficacious, their long-term usefulness has been questioned. This study examined the fate of LAGBs in a unit with over a decade of experience in their use. Patient factors related to the need for, and timing of, band removal were investigated.

Methods
A prospectively maintained database was used to identify all patients with a LAGB. Patient demographics, need for band removal and band survival were examined. Logistic regression modelling was done and Kaplan–Meier curves were calculated for band survival.

Results
Between 2000 and 2012, 674 bands were placed in 665 patients. Of these, 143 (21·2 per cent) were removed. There was no difference in rates of removal by sex (P = 0·910). The highest rates of removal were in patients aged less than 40 years (26·7 per cent), and those with a BMI greater than 60 kg/m2 (28·6 per cent). Earlier band removal was seen in younger patients (P = 0·002). Rates of removal increased linearly by earlier year of placement. Of bands placed 4 or more years previously, 35·0 per cent required removal. Eighty-three patients (58·0 per cent) who had a LAGB removed went on to have a further bariatric procedure (band to bypass, 66; band to sleeve, 17).

Conclusion
Even in experienced hands LAGB does not appear to be a definitive solution. In a large number of patients there appears to be a finite ‘band life’, with the majority of patients requiring conversion to a further bariatric procedure.
Presented in part to a meeting of the British Obesity and Metabolic Surgery Society, Glasgow, UK, January 2013, as an oral presentation for which it was awarded the council prize; published in abstract form as Br J Surg 2013; 100(Suppl 3): 2
Chiral Separation of Cathinone and Amphetamine Derivatives by HPLC/UV Using Sulfated ß‐Cyclodextrin as Chiral Mobile Phase Additive
Authors: Taschwer Magdalena , Seidl Yvonne , Mohr Stefan , Schmid Martin G. 
Published: June 2014

ABSTRACTIn the last years the identification of new legal and illegal highs has become a huge challenge for the police and prosecution authorities. In an analytical context, only a few analytical methods are available to identify these new substances. Moreover, many of these recreational drugs are chiral and it is supposed that the enantiomers differ in their pharmacological potency. Since nonenantioselective synthesis is easier and cheaper, they are mainly sold as racemic mixtures. The goal of this research work was to develop an inexpensive method for the chiral separation of cathinones and amphetamines. This should help to discover if the substances are sold as racemic mixtures and give further information about their quality as well as their origin. Chiral separation of a set of 6 amphetamine and 25 cathinone derivatives, mainly purchased from various Internet shops, is presented. A LiChrospher 100 RP‐18e, 250 x 4 mm, 5 µm served as the stationary phase. The chiral mobile phase consisted of methanol, water, and sulfated ß‐cyclodextrin. Measurements were performed under isocratic conditions in reversed phase mode using UV detection. Four model compounds of the two substance classes were used to optimize the mobile phase. Under final conditions (methanol:water 2.5:97.5 + 2% sulfated ß‐cyclodextrin) enantiomers of amphetamine and five derivatives were baseline separated within 23 min. In all, 17 cathinones were completely or partially chirally separated. However, as only 3 of 25 cathinones were baseline resolved, the application of this method is limited for cathinone analogs. Additionally, the results were compared with an RP‐8e column. Chirality 26:411–418, 2014. © 2014 Wiley Periodicals, Inc.
Molecular characterization of 54 cases of false‐negative fine‐needle aspiration among 1347 papillary thyroid carcinomas
Authors: Proietti Agnese , Borrelli Nicla , Giannini Riccardo , Romani Rossana , Di Coscio Giancarlo , Quilici Francesca , Rago Teresa , Miccoli Paolo , Vitti Paolo , Basolo Fulvio 
Published: June 2014

BACKGROUNDFine‐needle aspiration (FNA) has been widely accepted as the most crucial step in the preoperative assessment of thyroid nodules, but the false‐negative rates are generally reported to be between 3.6% and 10.2%. To lower the overall incidence of this false‐negative testing, new reporting systems encourage the molecular testing of thyroid nodules. However, to the authors' knowledge, the role of molecular testing in false‐negative FNA has not yet been evaluated.METHODSIn total, 1347 consecutive papillary thyroid carcinomas (PTCs) with both cytological and histological diagnoses were collected from the same center. A blinded revision of the false‐negative cases was performed. An analysis of the BRAF and Ras genes in the false‐negative cases was then performed.RESULTSThe false‐negative rate at the time of primary FNA diagnosis was 4.8% (65 of 1347 cases). False‐negative cases were 15 follicular variant PTCs, 2 classical variant, and 1 solid variant that lacked peculiar PTC cytomorphological features. Adequate cellular material for molecular analysis was available only in 54 of the 65 false‐negative cases. Mutations were found in 6 cases (11%), and Ras alterations were present in 16 cases (29.6%). The addition of molecular analysis decreased the false‐negative rate to 0.4% (5 of 1347 cases).CONCLUSIONSThe results of the current study confirm the feasibility of BRAF and Ras analysis in routine FNA. However, when the false‐negative FNA rate is low, the cost‐benefit analysis of the detection of BRAF and Ras mutations should be carefully evaluated. Consequently, the authors suggest that preoperative molecular assessment could be helpful for benign nodules, but only in the presence of clinical suspicion of malignancy. Cancer (Cancer Cytopathol) 2014;122:751–759. © 2014 American Cancer Society.
A latent class analysis to empirically describe eating disorders through developmental stages
Authors: Swanson Sonja A. , Horton Nicholas J. , Crosby Ross D. , Micali Nadia , Sonneville Kendrin R. , Eddy Kamryn , Field Alison E. 
Published: June 2014

ABSTRACTObjectivesThe current standards for classifying eating disorders were primarily informed by adult, clinical study populations, while it is unknown whether an empirically based classification system can be supported across preadolescence through young adulthood. Using latent class analyses, we sought to empirically classify disordered eating in females from preadolescence to young adulthood, and assess the association between classes and adverse outcomes.MethodLatent class models were fit using observations from the 9,039 girls participating in the growing up today study, an on‐going cohort following participants annually or biennially since 1996 when they were ages 9–14 years. Associations between classes and drug use, binge drinking, and depressive symptoms were assessed using generalized estimating equations.ResultsAcross age groups, there was evidence of six classes: a large asymptomatic class, a class characterized by shape/weight concerns, a class characterized by overeating without loss of control, and three resembling full and subthreshold binge eating disorder, purging disorder, and bulimia nervosa. Relative prevalences of classes varied across developmental stages, with symptomatic classes increasing in prevalence with increasing age. Symptomatic classes were associated with concurrent and incident drug use, binge drinking, and high depressive symptoms.DiscussionA classification system resembling broader definitions of DSM‐5 diagnoses along with two further subclinical symptomatic classes may be a useful framework for studying disordered eating among adolescent and young adult females. © 2014 Wiley Periodicals, Inc. Int (J Eat Disord 2014; 47:762–772)
Reduction of Discretization Errors of Dynamics with Variable Structures and Its Realization Using FPGA
Authors: Kaneda Yasuaki , Irizuki Yasuharu , Sadahiro Teruyoshi , Yamakita Masaki 
Published: June 2014

SUMMARYIn order to discretize continuous dynamics with variable structures, Euler integrators are often used. However, Euler integrators include large discretization errors, so that they reduce the performance in the discretized dynamics. The use of Richardson extrapolation (RE) and fractional delay (FD) can reduce the discretization errors. However, Euler integrators using RE and FD directly have infinite gains at the Nyquist frequencies, and they are unsuitable for integrations of dynamics with variable structures. In this paper, we propose an improved integrator that is suitable for the integration of dynamics with variable structures. The proposed method consists of a high forward gain and a feedback structure with a high‐precision differentiator. To realize the high‐precision differentiator, RE and a high sampling rate (HSR) are used instead of FD, and these are implemented using a field programmable gate array (FPGA). The effectiveness is verified through software simulations, hardware in the loop (HIL) simulations, and experiments.
Adherence to climate change‐related ingroup norms: Do dimensions of group identification matter?
Authors: Masson Torsten , Fritsche Immo 
Published: June 2014

AbstractRecent research provides evidence that group norms influence intentions to engage in pro‐climate behaviour and that identification with the group moderates the norm effects. However, past studies have neglected to examine if the effects on norm adherence vary among different identification aspects. The present studies close this gap by investigating group‐level self‐investment (i.e. the importance of and satisfaction with the group) and self‐definition (i.e. perceived similarities among group members) as possible moderators of group norm effects. We used two experimental studies to test our assumption that self‐investment but not self‐definition would moderate the norm‐intention relation. The results support our assumption and show that group members who were highly self‐invested in the group (but did not necessarily perceive themselves as similar to other group members) adhered more strongly to climate‐related ingroup norms than less self‐invested group members. However, perceived similarity among group members (i.e. self‐definition) did not positively contribute to respondents' decision to conform to a group norm. Copyright © 2014 John Wiley & Sons, Ltd.
On attitudes towards humanity and climate change: The effects of humanity esteem and self‐transcendence values on environmental concerns
Authors: Cheung Wing‐Yee , Luke Michelle A. , Maio Gregory R. 
Published: June 2014

AbstractIn climate change communications, do attitudes towards humans influence pro‐environmental action? If so, does it depend on endorsement of self‐transcendence values? Two experiments examined these questions by assessing the effects of activating positive (vs. negative) humanity esteem on environmental motives, personal moral norms, and behavioural intentions to protect the environment. The experiments tested whether the effects of humanity esteem depend on individuals' self‐transcendence values. Results indicated that among people who endorse self‐transcendence values less strongly, those in the positive (vs. negative) humanity‐esteem condition had lower ecocentrism (Experiment 1) and weaker personal norms, which led to weaker behavioural intentions to protect the environment (Experiment 2). In contrast, across the two humanity‐esteem conditions, people who more strongly endorsed self‐transcendence values showed stronger ecocentrism, personal moral norms, and behavioural intentions to protect the environment. Thus, for people with weaker self‐transcendence values, portrayals of humanity play a role in people's engagement with environmental causes. Copyright © 2014 John Wiley & Sons, Ltd.
Sources of uncertainty in estimating stream solute export from headwater catchments at three sites
Authors: Yanai Ruth D. , Tokuchi Naoko , Campbell John L. , Green Mark B. , Matsuzaki Eiji , Laseter Stephanie N. , Brown Cindi L. , Bailey Amey S. , Lyons Pilar , Levine Carrie R. , Buso Donald C. , Likens Gene E. , Knoepp Jennifer D. , Fukushima Keitaro 
Published: June 2014

AbstractUncertainty in the estimation of hydrologic export of solutes has never been fully evaluated at the scale of a small‐watershed ecosystem. We used data from the Gomadansan Experimental Forest, Japan, Hubbard Brook Experimental Forest, USA, and Coweeta Hydrologic Laboratory, USA, to evaluate many sources of uncertainty, including the precision and accuracy of measurements, selection of models, and spatial and temporal variation. Uncertainty in the analysis of stream chemistry samples was generally small but could be large in relative terms for solutes near detection limits, as is common for ammonium and phosphate in forested catchments. Instantaneous flow deviated from the theoretical curve relating height to discharge by up to 10% at Hubbard Brook, but the resulting corrections to the theoretical curve generally amounted to <0.5% of annual flows. Calibrations were limited to low flows; uncertainties at high flows were not evaluated because of the difficulties in performing calibrations during events. However, high flows likely contribute more uncertainty to annual flows because of the greater volume of water that is exported during these events. Uncertainty in catchment area was as much as 5%, based on a comparison of digital elevation maps with ground surveys. Three different interpolation methods are used at the three sites to combine periodic chemistry samples with streamflow to calculate fluxes. The three methods differed by <5% in annual export calculations for calcium, but up to 12% for nitrate exports, when applied to a stream at Hubbard Brook for 1997–2008; nitrate has higher weekly variation at this site. Natural variation was larger than most other sources of uncertainty. Specifically, coefficients of variation across streams or across years, within site, for runoff and weighted annual concentrations of calcium, magnesium, potassium, sodium, sulphate, chloride, and silicate ranged from 5 to 50% and were even higher for nitrate. Uncertainty analysis can be used to guide efforts to improve confidence in estimated stream fluxes and also to optimize design of monitoring programmes. © 2014 The Authors. Hydrological Processes published John Wiley & Sons, Ltd.
CCN1 Secreted by Tonsil‐Derived Mesenchymal Stem Cells Promotes Endothelial Cell Angiogenesis via Integrin αvβ3 and AMPK
Authors: Park Yoon Shin , Hwang Soojin , Jin Yoon Mi , Yu Yeonsil , Jung Sung‐Ae , Jung Sung‐Chul , Ryu Kyung‐Ha , Kim Han Su , Jo Inho 
Published: June 2014

AbstractCCN1 is highly expressed in cancer cells and has been identified in the secretome of bone marrow‐derived mesenchymal stem cells (BM‐MSC). Although secreted CCN1 is known to promote angiogenesis, its underlying mechanism remains unclear. Here, we examined whether our recently‐established tonsil‐derived MSC (T‐MSC) secrete CCN1 and, if any, how CCN1 promotes the angiogenesis of human umbilical vein endothelial cells (HUVEC). Compared with untreated control T‐MSC, a higher level of CCN1 was secreted by T‐MSC treated with activin A and sonic hedgehog, drugs known to induce endodermal differentiation. Expectedly, conditioned medium collected from differentiated T‐MSC (DCM) significantly increased HUVEC migration and tube formation compared with that from control T‐MSC (CCM), and these stimulatory effects were reversed by neutralization with anti‐CCN1 antibody. Treatment with recombinant human CCN1 (rh‐CCN1) alone also mimicked the stimulatory effects of DCM. Furthermore, treatment with either DCM or rh‐CCN1 increased the phosphorylation of AMP kinase (AMPK), and ectopic expression of siRNA of the AMPK gene inhibited all observed effects of both DCM and rh‐CCN1. However, no alteration of intracellular ATP levels or phosphorylation of LKB1, a well‐known upstream factor of AMPK activation, was observed under our conditions. Finally, the neutralization of integrin αvβ3 with anti‐integrin αvβ3 antibody almost completely reversed the effects of CCN1 on AMPK phosphorylation, and EC migration and tube formation. Taken together, we demonstrated that T‐MSC increase the secretion of CCN1 in response to endodermal differentiation and that integrin αvβ3 and AMPK mediate CCN1‐induced EC migration and tube formation independent of intracellular ATP levels alteration. J. Cell. Physiol. 230: 140–149, 2015. © 2014 Wiley Periodicals, Inc.
Surface‐enhanced Raman scattering for the analysis of red lake pigments in painting layers mounted in cross sections
Authors: Idone Ambra , Aceto Maurizio , Diana Eliano , Appolonia Lorenzo , Gulmini Monica 
Published: June 2014

Cross sections are very useful in the scientific investigation of paintings and polychromies as they show the sequence of the layers and allow the detection of colorants in each layer through micro‐Raman spectroscopy. Surface‐enhanced Raman scattering (SERS) presently represents the most promising tool to overcome the limits of a traditional micro‐Raman approach in the investigation of painting materials containing fluorescent organic dyes. Among the SERS substrates, silver colloidal pastes are suitable to analyze minute samples by drop‐coating them with the paste, without the need of specific pre‐treatments. The application of silver colloidal pastes has been explored here on two cross sections obtained from the 13th century painted wooden statue and from the 16th century mural painting.The main issue when employing such a substrate consists in achieving a suitable coating on the complex surfaces under investigation. In this work, some tests were devoted to enable the display of coated samples through the microscope coupled to the Raman spectrometer and to enhance the signals from lake pigments. The analytical procedure was successful in gaining SER spectra from the sections: the red, highly fluorescent pigment grains were identified as lake pigments obtained by kermes and by a purpurin‐rich plant dyestuff. SER signals were discussed by considering SER spectra obtained from pure substances and/or reference materials and data reported in the literature.The work represents a further step toward the possibility of fully exploiting the high spatial resolution of the micro‐Raman spectrometer to investigate samples from painted objects. Copyright © 2014 John Wiley & Sons, Ltd.
CD44+CD324− expression and prognosis in gastric cancer patients
Authors: Cao Liang , Hu Xiang , Zhang Jian , Liang Pin , Zhang Yi 
Published: June 2014

AbstractPurposeTo evaluate the frequency of cancer stem cell marker CD44 combined CD324 expression in gastric cancer specimens and association of the expression with survival of gastric cancer patients.MethodsA total of 203 patients with primary gastric cancer who underwent curative gastric resection with lymphadenectomy were studied. The expression of CD44 and CD324 was analyzed by immunohistochemistry and the association of CD44 and CD324 expression analyzed by clinicopathological characteristics. Survival of the patients was evaluated.ResultsCD44+CD324− tumors showed strong correlation with positive lymph node metastasis. Patients with CD44−CD324+ had a significantly better prognosis (54.8%) than that with CD44+CD324− (24.5%). A multivariate Cox proportional hazards model using those variables associated with survival in our study (depth of invasion, tumor size, lymph node metastasis, gastrectomy, CD44 expression, CD324 expression, CD44 and CD324 expression) revealed that CD44+CD324− expression (P = 0.005) was one of significant independent prognostic indicator, whereas CD44 expression (P = 0.081), CD324 expression (P = 0.068) was not.ConclusionCD44+CD324− expression was one of significant independent prognostic survival factors for patients with gastric cancer. J. Surg. Oncol. 2014 110:727–733. © 2014 Wiley Periodicals, Inc.
Retail Atmospherics and In‐Store Nonverbal Cues: An Introduction
Authors: Grewal Dhruv , Roggeveen Anne L. , Puccinelli Nancy M. , Spence Charles 
Published: June 2014

ABSTRACTCustomers' in‐store experiences are having a profound impact on their shopping behavior. In this special issue, two key variables are highlighted: the retail environment and role of nonverbal cues. The eight papers in this special issue present numerous cutting edge issues in these two research domains. Each of these papers and some of their salient contributions are briefly overviewed in this introductory editorial. The goal of this special issue (and the articles in it) is to serve as an impetus for additional research.
Store Atmospherics: A Multisensory Perspective
Authors: Spence Charles , Puccinelli Nancy M. , Grewal Dhruv , Roggeveen Anne L. 
Published: June 2014

ABSTRACTStore atmospherics affect consumer behavior. This message has created a revolution in sensory marketing techniques, such that across virtually every product category, retailers and manufacturers seek to influence the consumer's “sensory experience.” The key question is how should a company design its multisensory atmospherics in store to ensure that the return on its investment is worthwhile? This paper reviews the scientific evidence related to visual, auditory, tactile, olfactory, and gustatory aspects of the store environment and their influence on the consumer's shopping behavior. The findings emphasize the need for further research to address how the multisensory retail environment shapes customer experience and shopping behavior.
It Takes Just 120 Seconds: Predicting Satisfaction in Technical Support Calls
Authors: Hall Judith A. , Verghis Phil , Stockton William , Goh Jin X. 
Published: June 2014

ABSTRACTThis study investigated whether information gleaned from the first two minutes of technical support telephone conversations could predict the callers’ satisfaction with the technical support person. The first two minutes of 84 calls from employees of a company to their help desk (47 technical support persons) were measured using (1) new participants who listened to or read the conversations and rated their impressions of the technical support person and their satisfaction while playing the caller role (proxy callers), and (2) other raters who rated the caller and aspects of the interaction as a whole. A word count software program (Linguistic Inquiry and Word Count, LIWC) was also used to examine the support persons’ communication style. Proxy callers’ satisfaction, their ratings of the support persons’ behavior (particularly on items indicative of a positive, caller‐centered behavior style), and the support persons’ use of the first person singular category of the LIWC were all significant predictors of the original callers’ satisfaction. These findings have implications for companies’ selection and training of customer support employees.
The Effect of Voice Quality on Ad Efficacy
Authors: Wiener Hillary J. D. , Chartrand Tanya L. 
Published: June 2014

ABSTRACTExtensive research has examined how to make broadcast advertising as effective as possible. However, one area of advertising that has received little research is the effect of the announcer or spokesperson's voice on consumers’ reactions to the ad or the product being advertised. In this paper, we examine the effect of the announcer's voice quality, or an overall impression of his or her voice, on consumers’ purchasing intentions for a new service. We find that female listeners are most likely to purchase this service when they hear it advertised by a man who has a creaky voice, but least likely to purchase it when they hear it advertised by a woman with a creaky voice. Other voice qualities produce more moderate results. Men, in contrast, are relatively insensitive to the effect of voice quality.