bluuebunny/crossref_metadata_2025_split huggingface dataset:
Existence of non-singular stellar solutions within the context of electromagnetic field: a comparison between minimal and non-minimal gravity models
Authors: Naseer Tayyab , Said Jackson Levi 
Published: August 2024

AbstractIn this paper, we explore the existence of various non-singular compact stellar solutions influenced by the Maxwell field within the matter-geometry coupling based modified gravity. We start this analysis by considering a static spherically symmetric spacetime which is associated with the isotropic matter distribution. We then determine the field equations corresponding to two specific functions of this modified theory. Along with these models, we also adopt different forms of the matter Lagrangian. We observe several unknowns in these equations such as the metric potentials, charge and fluid parameters. Thus, the embedding class-one condition and a particular realistic equation of state is used to construct their corresponding solutions. The former condition provides the metric components possessing three constants, and we calculate them through junction conditions. Further, four developed models are graphically analyzed under different parametric values. Finally, we find all our developed solutions well-agreeing with the physical requirements, offering valuable insights for future explorations of the stellar compositions in this theory.
ARTIFICIAL INTELLIGENCE FOR INNOVATION: A BIBLIOMETRIC ANALYSIS AND STRUCTURAL VARIATION APPROACH
Authors: JABEUR SAMI BEN , STEF NICOLAE , ARFI WISSAL BEN 
Published: August 2024

Artificial intelligence (AI) has gained significant popularity in recent years. This study critically examines the existing literature on the role and potential of AI, machine learning (ML) and big data in driving innovation. To the best of our knowledge, no existing survey has provided a comprehensive overview of this topic. The aim of this paper is thus to provide a coherent overview of theoretical cornerstones as well as recent trends in research on AI and data analytics for innovation. Using various bibliometric analyses of themes including publication counts and trends, co-citations, co-authorship, and keyword co-occurrence, we infer the thematic structure of AI research in innovation for the period from 1991 to 2021. The publications are grouped into three major clusters, with Cluster 1 remaining a constantly dominant theme in the digital innovation publication landscape. Cluster 2 includes published studies on big data, which also received much research attention. Cluster 3, which is the most prominent, includes business performance, business analytics, and information systems. We also analyse publication citation counts in the literature using Poisson and negative binomial regressions. The results show that the structural variation approach provides a new method for tracking and evaluating the potential of freshly published studies in context. The findings of the current study will be significant in identifying new areas of research of potential interest to scholars and practitioners in the field of AI for innovation worldwide. We conclude this review with limitations and theoretical and practical orientations.
Electrochemical Dissolution Behavior of ZCuPb10Sn10 Alloy in NaNO3 Solution
Authors: Zhang Qingliang , Qu Ningsong 
Published: August 2024

Copper alloys, such as ZCuPb10Sn10, have been widely applied to friction pairs in various products. Surface texture, such as micro-dimple array has attracted significant attention from researchers worldwide to improve tribological performance. To generate micro-dimple array on ZCuPb10Sn10 alloy by electrochemical machining, it is essential to investigate the electrochemical dissolution behavior of ZCuPb10Sn10 in NaNO3 solution. In this paper, the electrochemical dissolution behavior of ZCuPb10Sn10 alloy in NaNO3 solution is investigated through experimental tests. Anodic polarization, Tafel polarization, and electrochemical impedance spectroscopy were conducted to investigate its passive and corrosion behavior. The microstructure and composition of the dissolved surfaces were analyzed under various conditions. Additionally, a model was proposed to explain the electrochemical dissolution process of ZCuPb10Sn10 alloy in NaNO3 solution under high pressure hydrostatic conditions. Ultimately, a NaNO3 solution with 10% in concentration and 20 °C in temperature was selected as the electrolyte and a micro-dimple array with an average diameter of 119.7 μm and a depth of 7.4 μm was successfully generated with through-mask electrochemical micromachining on the surface of ZCuPb10Sn10 alloy.
H3K18 Lactylation Potentiates Immune Escape of Non–Small Cell Lung Cancer
Authors: Zhang Cai , Zhou Lijie , Zhang Mingyuan , Du Yue , Li Cai , Ren Huijun , Zheng Lu 
Published: August 2024

Abstract
Recently discovered epigenetic modification lysine lactylation contributes to tumor development and progression in several types of cancer. In addition to the tumor-intrinsic effects, histone lactylation may mediate tumor microenvironment remodeling and immune evasion. In this study, we observed elevated pan–lysine lactylation and histone H3 lysine 18 lactylation (H3K18la) levels in non–small cell lung cancer (NSCLC) tissues, which was positively correlated with poor patient prognosis. Interruption of glycolysis by 2-deoxy-D-glucose and oxamate treatment and silencing of lactate dehydrogenase A and lactate dehydrogenase B reduced H3K18la levels and circumvented immune evasion of NSCLC cells by enhancing CD8+ T-cell cytotoxicity. Mechanistically, H3K18la directly activated the transcription of pore membrane protein 121 (POM121), which enhanced MYC nuclear transport and direct binding to the CD274 promoter to induce PD-L1 expression. In a mouse NSCLC xenograft model, combination therapy with a glycolysis inhibitor and an anti-PD-1 antibody induced intratumoral CD8+ T-cell function and exhibited strong antitumor efficacy. Overall, this work revealed that H3K18la potentiates the immune escape of NSCLC cells by activating the POM121/MYC/PD-L1 pathway, which offers insights into the role of posttranslational modifications in carcinogenesis and provides a rationale for developing an epigenetic-targeted strategy for treating NSCLC.
Significance: H3K18 lactylation supports immunosuppression in non-small cell lung cancer by inducing POM121 to increase MYC activity and PD-L1 expression, which can be reversed by metabolic reprogramming and immunotherapy treatment.
The Neurodevelopmental Protein POGZ Suppresses Metastasis in Triple-Negative Breast Cancer by Attenuating TGFβ Signaling
Authors: Heath John , Mirabelli Caitlynn , Annis Matthew G. , Sabourin Valerie , Hebert Steven , Findlay Steven , Kim HaEun , Witcher Michael , Kleinman Claudia L. , Siegel Peter M. , Orthwein Alexandre , Ursini-Siegel Josie 
Published: August 2024

Abstract
The pogo transposable element–derived zinc finger protein, POGZ, is notably associated with neurodevelopmental disorders through its role in gene transcription. Many proteins involved in neurological development are often dysregulated in cancer, suggesting a potential role for POGZ in tumor biology. Here, we provided experimental evidence that POGZ influences the growth and metastatic spread of triple-negative breast cancers (TNBC). In well-characterized models of TNBC, POGZ exerted a dual role, both as a tumor promoter and metastasis suppressor. Mechanistically, loss of POGZ potentiated TGFβ pathway activation to exert cytostatic effects while simultaneously increasing the mesenchymal and migratory properties of breast tumors. Although POGZ levels are elevated in human breast cancers, the most aggressive forms of TNBC tumors, including those with increased mesenchymal and metastatic properties, exhibit dampened POGZ levels, and low POGZ expression was associated with inferior clinical outcomes in these tumor types. Taken together, these data suggest that POGZ is a critical suppressor of the early stages of the metastatic cascade.
Significance: The POGZ neurodevelopmental protein plays dual functions in triple-negative breast cancers as a tumor promoter and metastasis suppressor, inhibiting TGFβ-regulated EMT to limit breast cancer metastatic progression.
Incorporating Individual‐Level Treatment Effects and Outcome Preferences Into Personalized Blood Pressure Target Recommendations
Authors: Ascher Simon B. , Kravitz Richard L. , Scherzer Rebecca , Berry Jarett D. , de Lemos James A. , Estrella Michelle M. , Tancredi Daniel J. , Killeen Anthony A. , Ix Joachim H. , Shlipak Michael G. 
Published: August 2024

Background
There are no shared decision‐making frameworks for selecting blood pressure (BP) targets for individuals with hypertension. This study addressed whether results from the SPRINT (Systolic Blood Pressure Intervention Trial) could be tailored to individuals using predicted risks and simulated preferences.

Methods and Results

Among 8202 SPRINT participants, Cox models were developed and internally validated to predict each individual's absolute difference in risk from intensive versus standard BP lowering for cardiovascular events, cognitive impairment, death, and serious adverse events (AEs). Individual treatment effects were combined using simulated preference weights into a net benefit, which represents a weighted sum of risk differences across outcomes. Net benefits were compared among those above versus below the median AE risk. In simulations for which cardiovascular, cognitive, and death events had much greater weight than the AEs of BP lowering, the median net benefit was 3.3 percentage points (interquartile range [IQR], 2.0–5.7), and 100% of participants had a net benefit favoring intensive BP lowering. When simulating benefits and harms to have similar weights, the median net benefit was 0.8 percentage points (IQR, 0.2–2.2), and 87% had a positive net benefit. Compared with participants at lower risk of AEs from BP lowering, those at higher risk had a greater net benefit from intensive BP lowering despite experiencing more AEs (
P
<0.001 in both simulations).

Conclusions
Most SPRINT participants had a predicted net benefit that favored intensive BP lowering, but the degree of net benefit varied considerably. Tailoring BP targets using each patient's risks and preferences may provide more refined BP target recommendations.
Subsequent Memory Effects in Cortical Pattern Similarity Differ by Semantic Class
Authors: Yu Christina , Huang Shenyang , Howard Cortney M. , Hovhannisyan Mariam , Clarke Alex , Cabeza Roberto , Davis Simon W. 
Published: August 2024

Abstract
Although living and nonliving stimuli are known to rely on distinct brain regions during perception, it is largely unknown if their episodic memory encoding mechanisms differ as well. To investigate this issue, we asked participants to encode object pictures (e.g., a picture of a tiger) and to retrieve them later in response to their names (e.g., word “tiger”). For each of four semantic classes (living-animate, living-inanimate, nonliving-large, and nonliving-small), we examined differences in the similarity in activation patterns (neural pattern similarity [NPS]) for subsequently remembered versus forgotten items. Higher NPS for remembered items suggests an advantage of within-class item similarity, whereas lower NPS for remembered items indicates an advantage for item distinctiveness. We expect NPS within class-specific regions to be higher for remembered than for forgotten items. For example, the parahippocampal cortex has a well-known role in scene processing [Aminoff, E. M., Kveraga, K., & Bar, M. The role of the parahippocampal cortex in cognition. Trends in Cognitive Sciences, 17, 379–390, 2013], and the anterior temporal and inferior frontal gyrus have well-known roles in object processing [Clarke, A., & Tyler, L. K. Object-specific semantic coding in human perirhinal cortex. Journal of Neuroscience, 34, 4766–4775, 2014]. As such, we expect to see higher NPS for remembered items in these regions pertaining to scenes and objects, respectively. Consistent with this hypothesis, in fusiform, parahippocampal, and retrosplenial regions, higher NPS predicted memory for subclasses of nonliving objects, whereas in the left inferior frontal and left retrosplenial regions, lower NPS predicted memory for subclasses of living objects. Taken together, the results support the idea that subsequent memory depends on a balance of similarity and distinctiveness and demonstrate that the neural mechanisms of episodic encoding differ across semantic categories.
Sir Francis Cook, Viscount of Monserrate, an Art Collector with Social and Scholastic Concerns
Authors: Neto Maria João , Neto Teresa 
Published: August 2024

Abstract
Sir Francis Cook, Viscount of Monserrate, was one of the most notable art collectors in the nineteenth century, exhibiting hundreds of Old Master’s paintings, among other collections, at his main residence in Richmond, near London. As for his country home, Cook rehabilitated Monserrate in Sintra, Portugal, an estate once leased by William Beckford – there, Cook selected fascinating pieces, evoking the famous novelist and collector. Adding to previous studies on Cook’s collection, this paper aims to assess his taste, motivations and counsel for creating the collections, as well as how the collection was managed for personal enjoyment, social, and scholastic concerns.
Compliance Factors in Malaysian Guidelines for Hadith Authentication
Authors: Bahrudin Mohamad Khalid , Suliaman Ishak , Adnan Mohamad Azrien Mohamed 
Published: August 2024

Abstract
In 2018, Ministry of Home Affairs (MOHA) of Malaysia issued the Guideline for Writing and Publishing Hadith Texts (Garis Panduan Penulisan dan Penerbitan Teks Hadith) through Hadith Review and Assessment Committee (HRAC) to ensure high-quality hadith texts. A survey of 61 industry representatives revealed a moderate compliance level with a mean score of 2.69. This study uses quantitative methods, including descriptive and inferential analysis, to identify factors influencing compliance. Ten factors were measured, such as guideline characteristics, author/editor bias, publication type, company orientation, promotional strategies, guideline producer, law enforcement impact, training, incentives, and bureaucracy. The survey instrument demonstrated high reliability (Cronbach’s Alpha = .903), and data analysis via SPSS 27 showed that most factors had high mean scores (> 3.68), except for publication type (2.21) and company orientation (2.00). Multiple regression analysis identified aggressive promotional strategies and law enforcement as significant positive influences on compliance.
The Dynamism of the Social Literary and Hermeneutical Streams in Qurʾanic Classical and Modern Exegesis Studies
Authors: Amir Selamat bin , Hilmi Ahmad Bazli Ahmad , Abdullah Mustaffa bin , Norasid Muhamad Alihanafiah 
Published: August 2024

Abstract
Among the Qurʾanic exegesis streams that have emerged due to social changes and current developments in human civilisation, such as [specific social changes and developments], are the social literary (tafsīr al-adabī al-ijtimāʿī) stream and the hermeneutic. Both streams have their framework, phase, and factor from the time of their emergence and have their position in the method of Qurʾanic exegesis. This study discusses these two streams as a central debate in line with the historical and philosophical correlation of the evolution from classical to modern interpretations from various perspectives and in the context of the Islamic and Western world. This qualitative study used library research and comparative study on the social literary stream and hermeneutic, supported by other related written materials. The study finds that the social literary stream and hermeneutics differ in origin and methodology. The social literary stream is an interpretation that discusses Qurʾanic verses with the aesthetic value of language literature and its correlation with the elements of society. It can solve problems, counter hostility towards Islam, and treat diseases that exist in society with the guidance of the Qurʾan. Hermeneutic is a method of interpreting or expressing meaning in a text, originally referring to the Bible, originated from Greek mythology, which then developed in Christian culture and is now beginning to influence the method of interpreting the Quran. It is unsuitable for interpreting the Qurʾan because it would raise doubts (skepticism and relativism) about the equation of the Qurʾanic text with ordinary texts.
Content Analysis Study of Prophetic Prayer Medicament in Kitab Tib MSS1653 Malay Medical Manuscript
Authors: Ibrahim Norhasnira , Shah Faisal Ahmad 
Published: August 2024

Abstract
Prophetic medicaments are mentioned in hadith literature, which records the sayings, actions, and approvals of the Prophet Muhammad. His teachings and practices serve various functions, including guidance on maintaining good health and treating illnesses. Historically, one of the well-known Prophetic medicaments found in Malay medical manuscripts is reciting prayers as protection against illness, to cure diseases, and for good health derived from hadith texts. Thus, this article delves into analyse of the Prophets’ prayer medicaments practiced in Malay medical treatment by focusing on the Kitab Tib MSS1653 manuscript. The study is descriptive library research by applying the qualitative content analysis method. The data was then analysed by using inductive, deductive, and comparative methods between hadith and Malay medical practices in healing diseases. The result shows that 17 hadiths were mentioned as prayer recitations in this manuscript and practiced by the Malay community in their medical treatment. It is proof that Prophetic prayer medicament and Malay medical treatment are important and complement physical treatments by reciting prayers and seeking divine assistance as integral parts of the healing process.
Gagasan Malaysia Madani: Analisis Korelasi Enam Nilai Teras Ketamadunan Daripada Kisah Nabi Sulayman (As) Dalam Surah Al-Naml
Authors: Nasir Khairulnazrin , Zaman Rahim Kamarul , Ahmad Khalilullah Amin 
Published: August 2024

Abstract
Al-Quran has provided theoretical and practical guidance on the position of state institutions in Islam. One of the surahs that discusses the principles of statehood is Surah al-Naml. This surah, which contains 93 verses, tells the story of Prophet Sulayman (PBUH), a prophet and king who was blessed with wisdom and a great empire. Lately, there have been concerns over the erosion of values and integrity due to the spread of materialism, individualism, and hedonism. This has guided the idea of Madani Malaysia, which was introduced by the 10th Prime Minister of Malaysia, Anwar Ibrahim, in January 2023 to optimally apply core values to the people and leaders. Meanwhile, the story of Prophet Sulayman (PBUH) is a civilisation highlighted by the Quran in Surah al-Naml. However, is there a correlation between the core values of Madani Malaysia and the values contained in the story of Prophet Sulayman (PBUH)? This question leads to this study, which tries to identify the correlation aspect between the two core values. Using a qualitative approach based on literature, content analysis was conducted on the official documents of Madani Malaysia and the scholars’ interpretation of the story of Prophet Sulayman (PBUH). The findings of the study show that the six core values of Madani Malaysia, namely sustainability, well-being, creativity, respect, confidence, and courtesy have a significant link with the lessons and values contained in the story of Prophet Sulayman (PBUH), whether in His Majesty’s own character, ants, hudhud, Queen Balqis, and the dignitaries, both conceptually and practically. Overall, the application of these core values can drive Malaysia towards a developed and highly civilised country.
الاكتئاب النفسي، أسبابه وعلاجه في ضوء القران الكريم: دراسة تطبيقية على حالة الجالية اليمنية في ماليزيا
Authors: Amer Abdulwahab Mahyoub Murshed , Murshed Zinab Abdulwahab Mahyoub 
Published: August 2024

Abstract
According to the Quran, depression in general is attributed to a lack of religious commitment among Muslims, as well as the accumulation of sadness, anxiety, fear, disorder, psychological pressure, and issues related to family, social, cultural, economic, and political relationships. In the light of the challenges faced by the Yemeni community in Malaysia due to forced displacement from Yemen and the resulting lack of security from this traumatic experience and the inability to return, this study aims to uncover the nature, causes, and effects of psychological depression. Additionally, it seeks to identify proposals for alleviating symptoms based on the perspectives of a sample of 45 individuals from the Yemeni community in Malaysia. The researchers employed descriptive and analytical methods, and the study’s theoretical findings were consistent with field observations. The primary cause of depression was found to be fear for the well-being of loved ones, with significant impact stemming from anxiety and stress about the future. One of the key suggestions for alleviation was fostering certainty in future benefits.
Forgotten Buddhist Literatures as Revealed by Manuscript Discoveries in India and Beyond
Authors: Salomon Richard G. 
Published: August 2024

Abstract
In the early phases of the modern study of Buddhism, it was widely assumed that the Buddhist canon preserved in the Pali language by the Theravāda tradition of Sri Lanka and Southeast Asia represented the only original record of the “words of the Buddha” (buddha-vacana). But the notion of Pali primacy has been steadily eroded by discoveries of vast numbers of early Buddhist manuscripts in the formerly Buddhist regions of northwestern India and adjoining countries and in Central Asia. These discoveries have provided ample evidence of the existence in antiquity of voluminous bodies of Buddhist literature in Sanskrit and Gandhari that are parallel to and as historically valid as the Pali versions. They have shifted the perception of Buddhism away from a linear model and toward a wider understanding of the many Buddhisms that coexisted in antiquity. This article surveys some of the major discoveries of Buddhist manuscripts and summarizes the new perspectives that they have engendered.
Understanding Variation in Integrated STEM Practice as Measured by the STEM Observation Protocol (STEM-OP)
Authors: Dare Emily A. , Ring-Whalen Elizabeth A. 
Published: August 2024

Abstract
To better understand integrated STEM education, this work explored scores on the STEM Observation Protocol (STEM-OP), a newly developed observation protocol for use in K-12 science and engineering classrooms. The goals of this work were to better understand how integrated STEM might look throughout an integrated STEM unit and identify limitations of the instrument when examining daily scores and full unit implementation scores. The work takes a mixed methods approach to first examine what scores may be typically seen with daily and unit implementations. After identifying an exemplar integrated curriculum unit with consistently high daily scores, the authors qualitatively explore the fluctuations in protocol scores over the course of a curriculum unit implementation. Our work reveals that some items on the protocol may vary throughout implementation, while also demonstrating that achieving the highest scores on all items during one lesson or even throughout a full curriculum unit is challenging.