bluuebunny/crossref_metadata_2025_split huggingface dataset:
Resident-to-Resident Abuse: A Scoping Review
Authors: McDonald Lynn , Sheppard Christine , Hitzig Sander L. , Spalter Tal , Mathur Avantika , Mukhi Jason Singh 
Published: March 2015

RÉSUMÉL'abus de résidents par d'autres résidents parmi de foyers de soins de longue durée (SLD) implique l'agressivité et la violence et peut avoir des conséquences graves pour tous les deux, agresseurs et victimes. Jusqu'à présent, il n'y a eu aucune tentative d'évaluer systématiquement la portée de ce problème au Canada. Pour combler cette lacune, nous avons entrepris une étude de délimitation de l'étendue pour améliorer la compréhension de l'abus chez les résidents des foyers de SLD. Nous présentons aussi un ensemble redigé de données canadiennes sur l'abus chez les résidents. On a cherché neuf bases de données bibliographiques électroniques; un total de 784 résumés a été trouvés, mais seulement 32 ont satisfait les critères d'inclusion. La majorité des documents (75 pour cent) étaient des études de cas rétro-perspectives, des études qualitatives et critiques/commentaires. Parmi eux, seuls 14 se consacrent exclusivement à l'abus parmi les résidents. L'ensemble redigé de données canadiennes suggère que l'abus des résidents par d'autres résidents représente environ un tiers des cas d'abus signalés. Afin de faire connaître cette phénomène et d'aider à diminuer son incidence, des recommandations pour la recherche future, la pratique clinique et la politique sont fournis.
Team-based clinical simulation in radiation medicine: value to attitudes and perceptions of interprofessional collaboration
Authors: Gillan Caitlin , Giuliani Meredith , Wong Olive , Harnett Nicole , Milne Emily , Moseley Douglas , Thompson Robert , Catton Pamela , Bissonnette Jean-Pierre 
Published: March 2015

AbstractIntroductionSimulation has been effective for changing attitudes towards team-based competencies in many areas, but its role in teaching interprofessional collaboration (IPC) in radiation medicine (RM) is unknown. This study reports on feasibility and IPC outcomes of a team-based simulation event; ‘Radiation Medicine Simulation in Learning Interprofessional Collaborative Experience’ (RM SLICE).MethodsRadiation therapy (RTT), medical physics (MP) and radiation oncology (RO) trainees in a single academic department were eligible. Scheduled closure of a modern RM clinic allowed rotation of five high-fidelity cases in three 105-minute timeslots. A pre/post-survey design evaluated learner satisfaction and interprofessional perceptions. Scales included the Readiness for Interprofessional Learning Scale (RIPLS), UWE Entry Level Interprofessional Questionnaire (UWEIQ), Trainee Test of Team Dynamics and Collaborative Behaviours Scale (CBS).ResultsTwenty-one trainees participated; six ROs (28·57%), six MPs (28·57%) and nine RTTs (42·86%). All cases were conducted, resolved and debriefed within the allotted time. Twenty-one complete sets (100%) of evaluations were returned. Participants reported limited interaction with other professional groups before RM SLICE. Perceptions of team functioning and value of team interaction in ‘establishing or improving the care plan’ were high for all cases, averaging 8·1/10 and 8·9/10. Average CBS scores were 70·4, 71·9 and 69·5, for the three cases, scores increasing between the first and second case for 13/21 (61·9%) participants. RIPLS and UWEIQ scores reflected positive perceptions both pre- and post-event, averaging 83·5 and 85·2 (RIPLS) and 60·6 and 55·7 (UWEIQ), respectively. For all professions for both scales, the average change in score reflected improved IP perceptions, with agreement between scales for 15/20 (75·0%) participants. Overall, perception of IPC averaged 9·14/10, as did the importance of holding such an event annually.ConclusionsTeam-based simulation is feasible in RM and appears to facilitate interprofessional competency-building in high-acuity clinical situations, reflecting positive perceptions of IPC.
Higher diversity and abundance of denitrifying microorganisms in environments than considered previously
Authors: Wei Wei , Isobe Kazuo , Nishizawa Tomoyasu , Zhu Lin , Shiratori Yutaka , Ohte Nobuhito , Koba Keisuke , Otsuka Shigeto , Senoo Keishi 
Published: March 2015

Abstract
Denitrification is an important process in the global nitrogen cycle. The genes encoding NirK and NirS (nirK and nirS), which catalyze the reduction of nitrite to nitric oxide, have been used as marker genes to study the ecological behavior of denitrifiers in environments. However, conventional polymerase chain reaction (PCR) primers can only detect a limited range of the phylogenetically diverse nirK and nirS. Thus, we developed new PCR primers covering the diverse nirK and nirS. Clone library and qPCR analysis using the primers showed that nirK and nirS in terrestrial environments are more phylogenetically diverse and 2–6 times more abundant than those revealed with the conventional primers. RNA- and culture-based analyses using a cropland soil also suggested that microorganisms with previously unconsidered nirK or nirS are responsible for denitrification in the soil. PCR techniques still have a greater capacity for the deep analysis of target genes than PCR-independent methods including metagenome analysis, although efforts are needed to minimize the PCR biases. The methodology and the insights obtained here should allow us to achieve a more precise understanding of the ecological behavior of denitrifiers and facilitate more precise estimate of denitrification in environments.
Topological states in multi-orbital HgTe honeycomb lattices
Authors: Beugeling W. , Kalesaki E. , Delerue C. , Niquet Y.-M. , Vanmaekelbergh D. , Smith C. Morais 
Published: March 2015

AbstractResearch on graphene has revealed remarkable phenomena arising in the honeycomb lattice. However, the quantum spin Hall effect predicted at the K point could not be observed in graphene and other honeycomb structures of light elements due to an insufficiently strong spin–orbit coupling. Here we show theoretically that 2D honeycomb lattices of HgTe can combine the effects of the honeycomb geometry and strong spin–orbit coupling. The conduction bands, experimentally accessible via doping, can be described by a tight-binding lattice model as in graphene, but including multi-orbital degrees of freedom and spin–orbit coupling. This results in very large topological gaps (up to 35 meV) and a flattened band detached from the others. Owing to this flat band and the sizable Coulomb interaction, honeycomb structures of HgTe constitute a promising platform for the observation of a fractional Chern insulator or a fractional quantum spin Hall phase.
Testosterone regulates the autophagic clearance of androgen binding protein in rat Sertoli cells
Authors: Ma Yi , Yang Hao-Zheng , Xu Long-Mei , Huang Yi-Ran , Dai Hui-Li , Kang Xiao-Nan 
Published: March 2015

AbstractDysregulation of androgen-binding protein (ABP) is associated with a number of endocrine and andrology diseases. However, the ABP metabolism in Sertoli cells is largely unknown. We report that autophagy degrades ABP in rat Sertoli cells and the autophagic clearance of ABP is regulated by testosterone, which prolongs the ABP biological half-life by inhibiting autophagy. Further studies identified that the autophagic clearance of ABP might be selectively regulated by testosterone, independent of stress (hypoxia)-induced autophagic degradation. These data demonstrate that testosterone up-regulates ABP expression at least partially by suppressing the autophagic degradation. We report a novel finding with respect to the mechanisms by which ABP is cleared and by which the process is regulated in Sertoli cells.
Defect-Induced Photoluminescence Blinking of Single Epitaxial InGaAs Quantum Dots
Authors: Hu Fengrui , Cao Zengle , Zhang Chunfeng , Wang Xiaoyong , Xiao Min 
Published: March 2015

AbstractHere we report two types of defect-induced photoluminescence (PL) blinking behaviors observed in single epitaxial InGaAs quantum dots (QDs). In the first type of PL blinking, the “off” period is caused by the trapping of hot electrons from the higher-lying excited state (absorption state) to the defect site so that its PL rise lifetime is shorter than that of the “on” period. For the “off” period in the second type of PL blinking, the electrons relax from the first excited state (emission state) into the defect site, leading to a shortened PL decay lifetime compared to that of the “on” period. This defect-induced exciton quenching in epitaxial QDs, previously demonstrated also in colloidal nanocrystals, confirms that these two important semiconductor nanostructures could share the same PL blinking mechanism.
Imaging shear stress distribution and evaluating the stress concentration factor of the human eye
Authors: Joseph Antony S. 
Published: March 2015

AbstractHealthy eyes are vital for a better quality of human life. Historically, for man-made materials, scientists and engineers use stress concentration factors to characterise the effects of structural non-homogeneities on their mechanical strength. However, such information is scarce for the human eye. Here we present the shear stress distribution profiles of a healthy human cornea surface in vivo using photo-stress analysis tomography, which is a non-intrusive and non-X-ray based method. The corneal birefringent retardation measured here is comparable to that of previous studies. Using this, we derive eye stress concentration factors and the directional alignment of major principal stress on the surface of the cornea. Similar to thermometers being used for monitoring the general health in humans, this report provides a foundation to characterise the shear stress carrying capacity of the cornea and a potential bench mark for validating theoretical modelling of stresses in the human eye in future.
Lunge feeding in early marine reptiles and fast evolution of marine tetrapod feeding guilds
Authors: Motani Ryosuke , Chen Xiao-hong , Jiang Da-yong , Cheng Long , Tintori Andrea , Rieppel Olivier 
Published: March 2015

AbstractTraditional wisdom holds that biotic recovery from the end-Permian extinction was slow and gradual and was not complete until the Middle Triassic. Here, we report that the evolution of marine predator feeding guilds and their trophic structure, proceeded faster. Marine reptile lineages with unique feeding adaptations emerged during the Early Triassic (about 248 million years ago), including the enigmatic Hupehsuchus that possessed an unusually slender mandible. A new specimen of this genus reveals a well-preserved palate and mandible, which suggest that it was a rare lunge feeder as also occurs in rorqual whales and pelicans. The diversity of feeding strategies among Triassic marine tetrapods reached their peak in the Early Triassic, soon after their first appearance in the fossil record. The diet of these early marine tetrapods most likely included soft-bodied animals that are not preserved as fossils. Early marine tetrapods most likely introduced a new trophic mechanism to redistribute nutrients to the top 10 m of the sea, where the primary productivity is highest. Therefore, a simple recovery to a Permian-like trophic structure does not explain the biotic changes seen after the Early Triassic.
Ultra-broadband terahertz absorption by exciting the orthogonal diffraction in dumbbell-shaped gratings
Authors: Zang XiaoFei , Shi Cheng , Chen Lin , Cai Bin , Zhu YiMing , Zhuang SongLin 
Published: March 2015

AbstractMetamaterials, artificial electromagnetic media consisting of periodical subwavelength metal-based micro-structures, were widely suggested for the absorption of terahertz (THz) waves. However, they have been suffered from the absorption of THz waves just in the single-frequency owing to its resonance features. Here, in this paper, we propose a simple periodical structure, composed of two 90 degree crossed dumbbell-shaped doped-silicon grating arrays, to demonstrate broadband THz wave absorption. Our theoretical and experimental results illustrate that THz waves can be efficiently absorbed more than 95% ranging from 0.92 THz to 2.4 THz. Such an ultra-wideband polarization-independent THz absorber is realized mainly based on the mechanisms of the anti-reflection effect together with the [±1, 0]-order and [0, ±1]-order grating diffractions. The application of our investigation can be extend to THz couplers, filters, imaging and so on.
Strain-mediated electric-field control of exchange bias in a Co90Fe10/BiFeO3/SrRuO3/PMN-PT heterostructure
Authors: Wu S. Z. , Miao J. , Xu X. G. , Yan W. , Reeve R. , Zhang X. H. , Jiang Y. 
Published: March 2015

AbstractThe electric-field (E-field) controlled exchange bias (EB) in a Co90Fe10/BiFeO3 (BFO)/SrRuO3/PMN-PT heterostructure has been investigated under different tensile strain states. The in-plane tensile strain of the BFO film is changed from +0.52% to +0.43% as a result of external E-field applied to the PMN-PT substrate. An obvious change of EB by the control of non-volatile strain has been observed. A magnetization reversal driven by E-field has been observed in the absence of magnetic field. Our results indicate that a reversible non-volatile E-field control of a ferromagnetic layer through strain modulated multiferroic BFO could be achieved at room temperature.
An atmospheric origin of the multi-decadal bipolar seesaw
Authors: Wang Zhaomin , Zhang Xiangdong , Guan Zhaoyong , Sun Bo , Yang Xin , Liu Chengyan 
Published: March 2015

AbstractA prominent feature of recent climatic change is the strong Arctic surface warming that is contemporaneous with broad cooling over much of Antarctica and the Southern Ocean. Longer global surface temperature observations suggest that this contrasting pole-to-pole change could be a manifestation of a multi-decadal interhemispheric or bipolar seesaw pattern, which is well correlated with the North Atlantic sea surface temperature variability and thus generally hypothesized to originate from Atlantic meridional overturning circulation oscillations. Here, we show that there is an atmospheric origin for this seesaw pattern. The results indicate that the Southern Ocean surface cooling (warming) associated with the seesaw pattern is attributable to the strengthening (weakening) of the Southern Hemisphere westerlies, which can be traced to Northern Hemisphere and tropical tropospheric warming (cooling). Antarctic ozone depletion has been suggested to be an important driving force behind the recently observed increase in the Southern Hemisphere's summer westerly winds; our results imply that Northern Hemisphere and tropical warming may have played a triggering role at an stage earlier than the first detectable Antarctic ozone depletion and enhanced Antarctic ozone depletion through decreasing the lower stratospheric temperature.
Photothermal cellular stimulation in functional bio-polymer interfaces
Authors: Martino Nicola , Feyen Paul , Porro Matteo , Bossio Caterina , Zucchetti Elena , Ghezzi Diego , Benfenati Fabio , Lanzani Guglielmo , Antognazza Maria Rosa 
Published: March 2015

AbstractHybrid interfaces between organic semiconductors and living tissues represent a new tool for in-vitro and in-vivo applications, bearing a huge potential, from basic researches to clinical applications. In particular, light sensitive conjugated polymers can be exploited as a new approach for optical modulation of cellular activity. In this work we focus on light-induced changes in the membrane potential of Human Embryonic Kidney (HEK-293) cells grown on top of a poly(3-hexylthiophene) (P3HT) thin film. On top of a capacitive charging of the polymer interface, we identify and fully characterize two concomitant mechanisms, leading to membrane depolarization and hyperpolarisation, both mediated by a thermal effect. Our results can be usefully exploited in the creation of a new platform for light-controlled cell manipulation, with possible applications in neuroscience and medicine.
Voluntary rewards mediate the evolution of pool punishment for maintaining public goods in large populations
Authors: Sasaki Tatsuya , Uchida Satoshi , Chen Xiaojie 
Published: March 2015

AbstractPunishment is a popular tool when governing commons in situations where free riders would otherwise take over. It is well known that sanctioning systems, such as the police and courts, are costly and thus can suffer from those who free ride on other's efforts to maintain the sanctioning systems (second-order free riders). Previous game-theory studies showed that if populations are very large, pool punishment rarely emerges in public good games, even when participation is optional, because of second-order free riders. Here we show that a matching fund for rewarding cooperation leads to the emergence of pool punishment, despite the presence of second-order free riders. We demonstrate that reward funds can pave the way for a transition from a population of free riders to a population of pool punishers. A key factor in promoting the transition is also to reward those who contribute to pool punishment, yet not abstaining from participation. Reward funds eventually vanish in raising pool punishment, which is sustainable by punishing the second-order free riders. This suggests that considering the interdependence of reward and punishment may help to better understand the origins and transitions of social norms and institutions.
Wilms' tumor 1 (WT1) expression and prognosis in solid cancer patients: a systematic review and meta-analysis
Authors: Qi Xiao-wei , Zhang Fan , Wu Hong , Liu Jun-lan , Zong Bei-ge , Xu Chuan , Jiang Jun 
Published: March 2015

AbstractThough proposed as a promising target antigen for cancer immunotherapy, the prognostic value of Wilms' tumor 1 (WT1) in solid tumors remains inconclusive. Here, we report a systematic review and meta-analysis of the association between WT1 expression and prognosis in solid tumors. PubMed, Web of Science and Google Scholar were searched to identify studies exploring the impact of WT1 on clinical outcomes, including overall survival (OS), disease-specific survival (DSS), disease-free survival (DFS), relapse/recurrence-free survival (RFS) or progression-free survival (PFS), in solid cancer patients. Hazard ratio (HR) and 95% confidence interval (CI) were applied to assess the strength of these associations. Finally, a total of 29 eligible studies with 4090 patients were identified for qualitative analysis and 22 studies with 3620 patients were enrolled for quantitative synthesis. Overall, positive expression of WT1 was significantly associated with worse OS (metaHR = 1.48, 95% CI = 1.11–1.97) and DFS/RFS/PFS (metaHR = 2.14, 95% CI = 1.42–3.21). Subgroup analyses showed that WT1 positive expression could independently predict unfavorable DFS/RFS/PFS (metaHR = 1.86, 95%CI = 1.04–3.35). In summary, our study suggests that WT1 may be a potential marker to predict DFS/RFS/PFS in solid tumor patients. Further studies are needed to confirm the role of WT1 expression in clinical practice.
Subknots in ideal knots, random knots and knotted proteins
Authors: Rawdon Eric J. , Millett Kenneth C. , Stasiak Andrzej 
Published: March 2015

AbstractWe introduce disk matrices which encode the knotting of all subchains in circular knot configurations. The disk matrices allow us to dissect circular knots into their subknots, i.e. knot types formed by subchains of the global knot. The identification of subknots is based on the study of linear chains in which a knot type is associated to the chain by means of a spatially robust closure protocol. We characterize the sets of observed subknot types in global knots taking energy-minimized shapes such as KnotPlot configurations and ideal geometric configurations. We compare the sets of observed subknots to knot types obtained by changing crossings in the classical prime knot diagrams. Building upon this analysis, we study the sets of subknots in random configurations of corresponding knot types. In many of the knot types we analyzed, the sets of subknots from the ideal geometric configurations are found in each of the hundreds of random configurations of the same global knot type. We also compare the sets of subknots observed in open protein knots with the subknots observed in the ideal configurations of the corresponding knot type. This comparison enables us to explain the specific dispositions of subknots in the analyzed protein knots.
Critical evidence for the prediction error theory in associative learning
Authors: Terao Kanta , Matsumoto Yukihisa , Mizunami Makoto 
Published: March 2015

AbstractIn associative learning in mammals, it is widely accepted that the discrepancy, or error, between actual and predicted reward determines whether learning occurs. Complete evidence for the prediction error theory, however, has not been obtained in any learning systems: Prediction error theory stems from the finding of a blocking phenomenon, but blocking can also be accounted for by other theories, such as the attentional theory. We demonstrated blocking in classical conditioning in crickets and obtained evidence to reject the attentional theory. To obtain further evidence supporting the prediction error theory and rejecting alternative theories, we constructed a neural model to match the prediction error theory, by modifying our previous model of learning in crickets and we tested a prediction from the model: the model predicts that pharmacological intervention of octopaminergic transmission during appetitive conditioning impairs learning but not formation of reward prediction itself and it thus predicts no learning in subsequent training. We observed such an “auto-blocking”, which could be accounted for by the prediction error theory but not by other competitive theories to account for blocking. This study unambiguously demonstrates validity of the prediction error theory in associative learning.
Extensive phenotypic plasticity of a Red Sea coral over a strong latitudinal temperature gradient suggests limited acclimatization potential to warming
Authors: Sawall Yvonne , Al-Sofyani Abdulmoshin , Hohn Sönke , Banguera-Hinestroza Eulalia , Voolstra Christian R. , Wahl Martin 
Published: March 2015

AbstractGlobal warming was reported to cause growth reductions in tropical shallow water corals in both, cooler and warmer, regions of the coral species range. This suggests regional adaptation with less heat-tolerant populations in cooler and more thermo-tolerant populations in warmer regions. Here, we investigated seasonal changes in the in situ metabolic performance of the widely distributed hermatypic coral Pocillopora verrucosa along 12° latitudes featuring a steep temperature gradient between the northern (28.5°N, 21–27°C) and southern (16.5°N, 28–33°C) reaches of the Red Sea. Surprisingly, we found little indication for regional adaptation, but strong indications for high phenotypic plasticity: Calcification rates in two seasons (winter, summer) were found to be highest at 28–29°C throughout all populations independent of their geographic location. Mucus release increased with temperature and nutrient supply, both being highest in the south. Genetic characterization of the coral host revealed low inter-regional variation and differences in the Symbiodinium clade composition only at the most northern and most southern region. This suggests variable acclimatization potential to ocean warming of coral populations across the Red Sea: high acclimatization potential in northern populations, but limited ability to cope with ocean warming in southern populations already existing at the upper thermal margin for corals.