bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of bioactive cements incorporating zinc-bioglass nanoparticles on odontogenic and angiogenic potential of human dental pulp cells
Authors: Zhang Jun , Park Yong-Duk , Bae Won-Jung , El-Fiqi Ahmed , Shin Song-Hee , Lee Eun-Jung , Kim Hae-Won , Kim Eun-Cheol 
Published: September 2014

Background The objective of this study was to investigate the effects of bioactive calcium phosphate cements (CPC, α-tricalcium phosphate-based) incorporating zinc-bioglass (ZnBG) on the odontogenic differentiation and angiogenesis of human dental pulp cells (HDPCs). Methods BGs with varying concentrations of Zn (0, 2.5 and 5%) were produced via a sol-gel process. The proliferation of HDPCs on CPC/BGs was determined by MTS assay. Alizarin red staining, RT-PCR, and ALP activity were used to assess odontogenic differentiation, and western blot analysis was used to asses signaling pathways. In vitro angiogenesis was examined via mRNA expression of angiogenic genes and tubule formation. Results All cement formulations showed no cytotoxicity. The CPCs with ZnBG showed increased ALP activity, enhanced formation of mineralized nodules, and upregulated mRNA expression of DMP-1, DSPP, Runx2, and osterix in a time- and dose-dependent manner, relative to CPCs without Zn. ZnBG upregulated integrins α1, α2, β1, and β3 and activated integrin downstream signal pathways, such as p-FAK, p-Akt, p-paxillin, RhoA, MAPK, and NF-κB, as well as canonical and non-canonical Wnt signaling. In addition, ZnBG upregulated VEGF mRNA in HDPCs and increased the tubular structure in endothelial cells. Conclusions Our results demonstrate that ZnBG incorporated within CPCs activates odontogenic differentiation and promotes angiogenesis in vitro through integrin, Wnt, MAPK, and NF-κB pathways. Thus, CPCs incorporating ZnBG are promising matrices in tissue engineering to stimulate endodontic regeneration.
Effect of Pathology on Union of First Metatarsophalangeal Joint Arthrodesis
Authors: Korim Muhammad Tawfiq , Allen Patricia E. 
Published: September 2014

Background: Arthrodesis is an established treatment for symptomatic degeneration of the first metatarsophalangeal (MP) joint. The published case series have often been small with different surgeons using a variety of joint preparation and fixation methods. The nonunion frequency comparing the different pathologies has not been described. We describe the senior author’s results comparing the union of an MP arthrodesis in hallux valgus, hallux rigidus, inflammatory arthropathy, and salvage surgery with identical joint preparation and fixation methods. Methods: The logbook of the senior author was used to identify the first MP joint arthrodeses from 2003 to 2011. The radiographic data were reviewed on the Picture Archiving and Communication system to assess the severity of deformity, radiographic union, type of fixation, and need for revision surgery. If there was no definite radiographic union of the last radiograph, the medical notes were reviewed. In all, 134 MP joint arthrodeses were performed in 78 females and 38 males, with a mean age of 65 ± 12 years (range, 20-94). Fixation was achieved by crossed screws (124) and dorsal plate (10). The primary diagnoses were hallux valgus in 49 joints (36.6%), hallux rigidus in 46 joints (34%), inflammatory arthropathy in 34 joints (25.4%), and salvage surgery in 5 joints (3.7%). Results: The overall radiographic union rate was 91.8% (123/134). There were significantly more nonunions in the hallux valgus group (14.3% vs 0%, OR 16, P = .05). Conclusion: Biplanar cuts and crossed screw fixation gave similar union frequencies to published case series. Hallux valgus was associated with higher nonunion frequencies in this single surgeon series. It may be that the hallux valgus group needs a stronger construct to achieve comparable union frequencies to the hallux rigidus group. Level of Evidence: Level III, retrospective comparative study.
Family quality of life and child psychological well-being in Palestine: A pilot case study
Authors: Veronese Guido , Fiore Francesca , Castiglioni Marco , Natour Miras 
Published: September 2014

Summary Bringing to bear an ecological perspective on functioning and well-being, the present work investigated the relationship between impact of trauma in children living in war-like conditions and their parents’ quality of life (QoL). Seventy-four school-aged children completed self-report measures assessing their personal life satisfaction and perceptions of parental support. Fifty-three parents completed self-report measures assessing their own quality of life. Findings Although these Palestinian children presented a moderate degree of traumatization, they nonetheless continued to display considerable resources and functioning factors in terms of satisfaction with their families, school and environment. However, ‘social suffering’ on the part of families, which impacts on economic, social, political, and cultural aspects of health and well-being, may undermine the resources that children can draw on in adjusting to trauma. Applications Clinical and social work interventions should be targeted at strengthening aspects of positive functioning, rather than at ‘correcting’ symptoms protecting Palestinian social capital, in terms of cohesion at the levels of clan, family and community networks.
What is care coordination?
Authors: Schultz Ellen M , McDonald Kathryn M 
Published: September 2014

Introduction Care coordination is a high-priority area for improvement across healthcare systems, but no consensus definition of care coordination exists. Methods This article reviews published definitions of the term “care coordination,” identifies common themes among them, and presents a broad working definition of care coordination. Results The review identified 57 unique definitions of care coordination, ranging widely in the scope of participants, settings, and care processes included. Five major themes emerged from the definitions: care coordination involves numerous participants, is necessitated by interdependence among participants and activities, requires knowledge of others’ roles and resources, relies on information exchange, and aims to facilitate appropriate healthcare delivery. Only one definition identified included all five themes, and no one theme was found in a clear majority of definitions. The synthesized themes were incorporated into a broad working definition of care coordination, which has resulted in numerous uses (e.g. guide for systematic review of interventions, development of a measures repository, reference for this journal’s recast focus on the subject). Discussion Some ambiguity remains about the definition of care coordination, but the breadth of definitions in use underscores its widespread recognition as important for high-quality care. Even as understanding of care coordination continues to evolve, broad and flexible definitions can help guide the iterative process of developing conceptual models, testing them empirically, refining models, generating evidence about what works best, and ultimately improving the quality of care.
Factors influencing treatment outcome in patients with gastroesophageal reflux disease: outcome of a prospective pragmatic trial in Asian patients
Authors: Goh Khean Lee , Choi Kee Don , Choi Myung-Gyu , Hsieh Tsai-Yuan , Jung Hwoon-Yong , Lien Han-Chung , Menon Jayaram , Mesenas Steven , Park Hyojin , Sheu Bor-Shyang , Wu Justin CY 
Published: September 2014

AbstractBackgroundPredicting response to proton pump inhibitor (PPI) treatment can aid the effective management of gastroesophageal reflux disease (GERD). The aim was to investigate the predictors of symptomatic response to pantoprazole in Asian patients with GERD; the first study of its kind in Asian patients.MethodsAsian patients with GERD symptoms (N = 209) received pantoprazole 40 mg daily for 8 weeks in a multinational, prospective, open-label study. Response was assessed using ReQuest™. Baseline and demographic factors were examined using logistic regression to determine if they were related to treatment response.ResultsResponse rates were 44.3% (Week 4) and 63.6% (Week 8) in Asian patients versus 60.7% (P < 0.001) and 72.2% (P = 0.010) for the rest of the world. Higher response rates at 8 weeks occurred in patients with erosive reflux disease (ERD; 71.3%) versus those with non-erosive reflux disease (NERD) at baseline (48.5%). The presence of ERD (P = 0.0143) and lower ReQuest™-GI scores at baseline (P = 0.0222) were associated with response. Improvements in quality of life (QoL) and anxiety and depression at 4 and 8 weeks were associated with treatment response (bothP < 0.0001). Patient satisfaction correlated with treatment response (P < 0.0001), and improvement in anxiety and depression (P < 0.0001) and QoL (P < 0.0001).ConclusionsAsian patients with GERD, especially those with NERD, may have lower response rates to PPIs than Western populations. ERD and less severe gastrointestinal symptoms may help to predict symptomatic responses to PPIs in Asian patients.Trial RegistrationClinicalTrial.gov identifier:NCT00312806.
Enhanced sensitivity of surface plasmon resonance phase-interrogation biosensor by using oblique deposited silver nanorods
Authors: Chung Hung-Yi , Chen Chih-Chia , Wu Pin Chieh , Tseng Ming Lun , Lin Wen-Chi , Chen Chih-Wei , Chiang Hai-Pang 
Published: September 2014

Abstract
Sensitivity of surface plasmon resonance phase-interrogation biosensor is demonstrated to be enhanced by oblique deposited silver nanorods. Silver nanorods are thermally deposited on silver nanothin film by oblique angle deposition (OAD). The length of the nanorods can be tuned by controlling the deposition parameters of thermal deposition. By measuring the phase difference between the p and s waves of surface plasmon resonance heterodyne interferometer with different wavelength of incident light, we have demonstrated that maximum sensitivity of glucose detection down to 7.1 × 10-8 refractive index units could be achieved with optimal deposition parameters of silver nanorods.
Comparing mortality among adult, general intensive care units in England with varying intensivist cover patterns: a retrospective cohort study
Authors: Wilcox M Elizabeth , Harrison David A , Short Alasdair , Jonas Max , Rowan Kathryn M 
Published: September 2014

Abstract
Introduction
Research has demonstrated that intensivist-led care of the critically ill is associated with reduced intensive care unit (ICU) and hospital mortality. The objective of this study was to evaluate whether a relation exists between intensivist cover pattern (for example, number of days of continuous cover) and patient outcomes among adult general ICUs in England.

Methods
We conducted a retrospective cohort study by using data from a pooled case mix and outcome database of adult general critical care units participating in the Intensive Care National Audit & Research Centre (ICNARC) Case Mix Programme. Consecutive admissions to participating units for the years 2010 to 2011 were linked to a survey of intensivist cover practices. Our primary outcome of interest was mortality at ultimate discharge from acute-care hospital.

Results
The analysis included 80,122 patients admitted to 130 ICUs in 128 hospitals. Multivariable logistic regression analysis was used to assess the relation between intensivist cover patterns (days of continuous cover, grade of physician staffing at nighttime, and frequency of daily handovers) and acute hospital mortality, adjusting for patient case mix. No relation was seen between days of continuous cover by a single intensivist or grade of physician staffing at nighttime and acute hospital mortality. Acute hospital mortality and ICU length of stay were not associated with intensivist characteristics, intensivist full-time equivalents per bed, or years of clinical experience. Intensivist participation in handover was associated with increased mortality (odds ratio, 1.27; 95% confidence interval, 1.04 to 1.55); however, only nine units reported no intensivist participation.

Conclusions
We found no relation between days of continuous cover by a single intensivist or grade of physician staffing at nighttime and patient outcomes in adult, general ICUs in England. Intensivist participation in handover was associated with increased mortality; further research to confirm or refute this finding is required.
Preparation and performance of Ag-coated Cu flakes filled epoxy as electrically conductive adhesives
Authors: Ren Hu-Ming , Zhang Kai , Matthew Yuen MF , Fu Xian-Zhu , Sun Rong , Wong Ching-Ping 
Published: September 2014

Abstract
A low-cost and high performance Ag-coated Cu flakes filled epoxy was prepared as electrically conductive adhesives (ECAs) for light emitting diode (LED) packaging. As-prepared ECAs consisted of bisphenol-F-epoxy resin, micro-sized Ag-coated Cu flakes and other additives. The ECAs with content of 70 wt % Ag-coated Cu flakes pre-modified by silane coupling agent (SCA) exhibited much lower bulk resistivity (8.4*10−3 Ωcm) than that of ECA filled with 70 wt % Ag-coated Cu flakes without SCA modification (1.6*10−1 Ωcm). An appropriate content of diluent (below 20 wt %) was beneficial for the flakes’ regular dispersion in resin, which enhanced the electrical conductivity (10−4 ~ −10−5 Ωcm) and mechanical strength (>14 Mpa) of ECAs.
Morphological and molecular differentiation of genus Corbicula suggests that two species are sympatrically distributed in Datong Lake in the Central Yangtze River Basin
Authors: Wang Gui-Ping , Zhang Ting , Zhang Jian , Li De-Liang , Xiao Tiao-Yi 
Published: September 2014

AbstractBackgroundWhite and purple color morphs ofCorbiculahave been identified all over the world. Previous studies suggested that the distinct difference of inner shell color, especially for sympatric individuals, derived mainly from their different genetic constitutions, not just environmental conditions. Two color morphs ofCorbiculasympatric in Datong Lake were compared by both morphometric methods (shell length, shell height, and shell width) and genetic analysis (based on the mitochondrial cytochromecoxidase subunit I geneCOI-mtCOI) to explore their taxonomic relationship.ResultsMorphological analysis showed that there were no significant differences in the values of SH/SL, SW/SL, and SW/SH (P > 0.05) between the two color morphs. Meanwhile, there were no significant differences in measurable parameters among the four mitochondrial COI haplotypes (DT-1, DT-7, DT-19, and DT-31) (P > 0.05). The sequences of four haplotypes (DT-1, DT-7, DT-19, and DT-31) were identical to FW1, FW5, FW4, and FW3, respectively. Restriction fragment length polymorphism (RFLP) analysis showed that only the sequences of haplotype DT-7 could be digested by the restriction enzymeSacI into two fragments with 200/500 bp. Haplotype DT-31 was found only in one individual (white morph), while each of the other three haplotypes shared with both two color morphs. Phylogenetic analysis demonstrated that the four haplotypes were subdivided into two divergent clades among freshwater clades, and haplotype DT-7 was a divergent sister taxon to the other three.ConclusionsThe results indicated that there were no distinct differences on morphological measures between the two color morphs, and each color morph shared with all four mitochondrial COI haplotypes. Two species (DT-7 referred asCorbicula flumineaand DT-1, DT-19, and DT-31 asCorbicula leana) might coexisted in the Datong Lake. Therefore, a comprehensive study combining nuclear and mitochondrial data along with biological information should be performed to confirm this assumption.
Structural and Physicochemical Interpretation of GT-STAF Information Theory-Based Indices
Authors: Barigye Stephen J , Marrero-Ponce Yovani , Zupan Jure , Pérez-Giménez Facundo , Freitas Matheus P 
Published: September 2014

Abstract
The underlying structural and physicochemical interpretation of the recently defined information indices (denominated as GT-STAF indices) is examined, with the aim of gaining greater insight on the codified chemical information. It is found that these indices are related with molecular symmetry in the context of the defined molecular “fragment” model. Moreover, these indices are sensitive to structural differences, demonstrating gradual changes consistent with modifications in the molecular structure. A principal component analysis reveals that the GT-STAF indices generally codify conformational, physicochemical, and thermodynamic properties of amino acids. A study with aniline derivatives demonstrates that the GT-STAF indices do not directly correlate with the ionization constant (pKa); but rather require multivariate contributions to yield correlations comparable with univariate models for quantum chemical parameters, suggesting that the former codify some other form of electronic information orthogonal to the latter. Finally, an evaluation of atomic contributions to the molecular hydrophobicity in furylethylenes demonstrates that the GT-STAF approach generally approximates to chemical properties quite well.
Side Substituent Dependence of Photophysical Properties of 9-Arylanthracene-Based π-Conjugates
Authors: Jana Debabrata , Ghorai Binay K 
Published: September 2014

Abstract
Three new 9-arylanthracene-based π-conjugated derivatives with different side substituent (methyl, methoxy, and hexyloxy) were synthesized using Heck coupling/Horner–Emmons reaction in good yields (72–78%) and their photophysical properties investigated. The dependence of the photophysical properties on the side substituent methyl, methoxy, and hexyloxy has been discussed. The absorption maxima of the synthesized compounds in the solution possess similar absorption bands located at 420–423 nm. They are shown to be thermally stable and emit light in sky blue region (ca. 490 nm) in solution. Photoluminescence measurements show a 25–28 nm red shift between solution and powdered states indicated some aggregation in the solid state. The results of cyclic voltammetry measurements of the compounds show good reversibility, indicating that the compounds have good electrochemical stability.
Educational internet-resources: challenges to application in the hospitality industry
Authors: Малолетко Наталья , Maloletko Natalya , Малолетко Александр , Maloletko Aleksandr , Воробьева Татьяна , Vorobeva Tatyana 
Published: September 2014

The article deals with the issues connected with the application of educational internet-technologies to additional professional hospitality-specific training programmes. A critical analysis of the internetbased or internet-located educational resources has revealed a gap between classical education and online courses (MOOC – massive open online course). The authors propose the use of the Freemium model, which has been repeatedly tested by top universities all over the world. The article also provides the results of an analysis of federal educational resources – an aggregation of different federal educational agencies, federal educational institutions, federal projects and programs official websites, as well as federal educational portals. In the article, the authors also describe the results of their
research into the sufficiency and adequateness of the competences currently held by the hospitalityindustry personnel and viewed from the top management’s standpoint. The purpose of the research is to identify the personnel’s educational/training needs. The analysis of internet-resources as carried out by the authors of the article demonstrates a lack of free-of-charge online training courses or Freemiumbased
courses.
Reflecting on tourist systems development
Authors: Саранча Михаил , Sarancha Mikhail 
Published: September 2014

The article is devoted to the issues of the development of tourist systems, which are a complex integrated natural-social entities. Development is one of the tourist system transformation options, which rests of needs-driven human activity. Needs satisfaction is largely dependent on the goal formation and goal realization. The current needs of a potential tourist are materialized in an individual tourist product, which is regarded, from the economy perspective, as classic and modern. From the modern perspective, a tourist product is an externalization of experience (most of all, impressions) coming
from visitors, producers, sellers, and managers alike. Thus, modern tourist economy is primarily based on tourist experience (a visitor’s/guest’s impression and provider creativity) rather than on the classical advantages of territories/products (richness in resources, abundance of resources and product/service versatility, etc). Simultaneously, tourist product creation is increasingly co-produced. The development of tourist systems should be founded on sustainable development and reflexive symmetry. However, a tourist system development can sometimes have negative consequences closely related to geographical variation, personal viewpoint difference, and unfairness conceived.
Changes in the legislative regulation of the right to tourists´ freedom of movement
Authors: Гузеева Наталья , Guzeeva Natalya 
Published: September 2014

This article is devoted to analysis of current changes in legislation, which entailed new restrictions of constitutional right of citizens to freedom of movement. It is adopted on 28 December 2013 amendments to the
Federal law « On specially protected natural areas». According to the author, these changes contradict the current system of regulations, including three article of the Constitution of the Russian Federation. The article discusses the possible adverse eff ects of these innovations. The
author comes to the conclusion that changes in legislation, initially aimed at the protection and nature conservation, will lead to deterioration in
its condition.
Mediacja kulturowa w tłumaczeniu ustnym
Authors: Kruk-Junger Katarzyna 
Published: September 2014

Cultural mediation in interpreting
The article focuses on the problem of cultural mediation in interpreting and presents some of the most important theories regarding the topic. Firstly, the author tackles the question whether the interpreter should act as a cultural mediator at all. Then, she describes specific types of cultural differences and their influence on the communication. Finally, the article offers a list of some helpful rules established by the theoreticians, which can result helpful whenever the need for cultural mediation presents itself in interpreter’s work.
Rola mediów w komunikacji międzynarodowej na przykładzie wydarzeń frankfurckich z 1995 r.
Authors: Olechowska Paulina 
Published: September 2014

The Role of Media in International Communication as Illustrated by Events in Frankfurt in 1995
The article presents results of research into the media portrayal of events in Frankfurt in 1995, as presented in local and national press in Germany and Poland. This research relied on a qualitative analysis of the text. According to the research results, German press coverage took a more balanced approach, whereas its Polish counterpart often appeared to rely more on emotional appeals based on historical events. This research complements a broader body of inquiry into the role of media in international communication, with particular emphasis on the cooperation between Polish and German journalists.