bluuebunny/crossref_metadata_2025_split huggingface dataset:
SLOMO controls AUX1-mediated gravitropism through a non-proteolytic role for AUX1 ubiquitination
Authors: De Smet Ive , Pan Lixia , Zhu Shanshuo , Iacobini Francesca Romana , Yang Shao-Li , Neyt Pia , de Cotte Brigitte van , Swarup Ranjan , Geisler Markus , Gevaert Kris , Band Leah , Mellor Nathan 
Published: July 2024

Abstract

Gravity-directed growth ensures that shoots and roots grow upwards and downwards, respectively. To achieve this, the organ’s angle with respect to gravity drives the asymmetric redistribution of the plant hormone auxin and consequently differential elongation creating a curvature of the organ. In addition to efflux transporters, the auxin influx transporter AUXIN RESISTANT 1 (AUX1) is essential for auxin redistribution during root gravitropism. Our results provide a biochemical framework that includes the F-box protein SLOMO affecting, possibly indirectly, AUX1 levels, and SLOMO controlling the ubiquitination of K261, K264, and K266, which affects AUX1 auxin transport properties. This reveals a novel, non-proteolytic role for SLOMO-mediated ubiquitination of AUX1.
Impacts of emergent rigid vegetation patches on flow characteristics of open channels
Authors: Qiu Hunan , Li Peng , Wang Wen , Shi Peng , Zhang Jiao , Chen Hao 
Published: July 2024

ABSTRACT
This study examines the influence of emergent vegetation on flow dynamics in natural river systems using large eddy simulation. It specifically addresses alterations in flow velocity and turbulence characteristics within open channels with varying densities of vegetation. The findings reveal a marked reduction in flow velocity within vegetated areas due to the obstruction posed by vegetation and the dynamics of shear layers. The flow alteration manifests in two distinct phases: the formation of a stable wake region behind densely vegetated patches and a more gradual velocity recovery in areas with sparser vegetation. In non-vegetated downstream zones, flow velocity tends to stabilize over a distance. Regarding turbulence, the study identifies differing patterns: enhanced vortex structures and accelerated energy dissipation in sparsely vegetated areas, contrasted with reduced turbulence in densely vegetated patches. Quadrant analysis further elucidates that ejections and inward interactions are primary contributors to Reynolds stress within vegetation patches, whereas outward interactions and sweeps become dominant in downstream regions. These insights offer a deeper understanding of how aquatic vegetation shapes river hydrodynamics, providing valuable information for effective river management and ecological restoration strategies.
Sensitivity of creep parameters to pressure fluctuation of transient flow in viscoelastic pipes
Authors: Sun Qiang , Wang Xu , Wu Yuebin , Xu Ying , Wang Zhihao 
Published: July 2024

ABSTRACT

A stepwise method is one of the efficient approaches in the calibration of transient flow in viscoelastic pipes. However, there is the lack of comprehensive research on the calibration method for retarded time and creep compliance. Therefore, the sensitivity of the order of magnitude of the creep parameters in the presence of interactions to transient flow pressure damping and phase in the case of the two-element Kelvin–Voigt model is investigated. Also, the calibration methods of retarded time and creep compliance in the stepwise method of transient flow parameter calibration for viscoelastic pipes are proposed. The results indicate that the creep compliances do not affect the phase of the pressure fluctuations when the selected retarded times are greater than the order of magnitude 10−1. For the first Kelvin–Voigt element, when the order of magnitude of the retarded time exceeds 10−2, an increase in creep compliance results in an increase in the degree of damping of pressure fluctuations. When the order of magnitude of the retarded time is less than 10−2, the rule is reversed. For the second Kelvin–Voigt element, an increase in creep compliance results in an increase in the degree of damping of transient flow pressure fluctuations independent of the retarded time.
Identification of illicit discharges in sewer networks by an SWMM-Bayesian coupled approach
Authors: Yang Liyuan , Huang Biao , Liu Jiachun 
Published: July 2024

ABSTRACT
Illicit discharges into sewer systems are a widespread concern within China's urban drainage management. They can result in unforeseen environmental contamination and deterioration in the performance of wastewater treatment plants. Consequently, pinpointing the origin of unauthorized discharges in the sewer network is crucial. This study aims to evaluate an integrative method that employs numerical modeling and statistical analysis to determine the locations and characteristics of illicit discharges. The Storm Water Management Model (SWMM) was employed to track water quality variations within the sewer network and examine the concentration profiles of exogenous pollutants under a range of scenarios. The identification technique employed Bayesian inference fused with the Markov chain Monte Carlo sampling method, enabling the estimation of probability distributions for the position of the suspected source, the discharge magnitude, and the commencement of the event. Specifically, the cases involving continuous release and multiple sources were examined. For single-point source identification, where all three parameters are unknown, concentration profiles from two monitoring sites in the path of pollutant transport and dispersion are necessary and sufficient to characterize the pollution source. For the identification of multiple sources, the proposed SWMM-Bayesian strategy with improved sampling is applied, which significantly improves the accuracy.
Microgravity Survey to Evaluate Earthquake Effects on the Derbendikhan Dam Site, Iraq
Authors: Mousa Ahmed , Al-Bahadily Hayder , Mickus Kevin 
Published: July 2024

ABSTRACT
A microgravity investigation was conducted along the axis of the Derbendikhan rockfill dam in Iraq. The dam lies in an earthquake-prone area within the High Folded Zone of the Western Zagros Fold–Thrust Belt. The goal of the survey was to evaluate the expected subsurface damage that could threaten the stability of the dam due to the effects of a 7.3 magnitude earthquake and future earthquakes that cause foundation cracking and landslides. The survey consists of 324 microgravity stations distributed on four profiles. Residual gravity anomalies were obtained by removing the regional effect of a 5-m upward continuation filter. Several negative and positive anomalies are distinguishable in a residual anomalies map that reflects the subsurface heterogeneity within the clay material that makes up the dam. The results reveal that there are no recognizable indications regarding the evolution of subsurface channels after the earthquake was given. Furthermore, two prominent anomalies appear close to the right bank at roughly 21 m in depth. These positive and negative anomalies suggest that high- and low-density zones coincide with different degrees of compressional stresses caused by the earthquake. Two-dimensional modeling indicates several low (less compacted) and high (more compacted) density areas that warrant further investigation in terms of material strength. The results can be used as a guide for a drilling program to examine the sources of the anomalies.
Estimating Background Threshold Values for Risk Assessment
Authors: Tramm Kenneth S. , Minter Jason T. , Seaton Catherine A. 
Published: July 2024

ABSTRACT
Site investigations that anticipate soil screening within a risk-based corrective action (RBCA) program often require an understanding of naturally occurring or ambient soil conditions. Because most RBCA programs offer very limited, if any, pre-published values for naturally occurring metals (e.g., arsenic and lead), it is imperative that the risk assessment process be informed by defensible screening-level background threshold values (BTVs). In the absence of representative BTVs, conservative screening levels from the RBCA process may incorrectly “screen in” ambient conditions as a release (false positive or Type I error) when none has occurred. False positives add unnecessary cost and confusion to subsequent investigation or remediation decisions. This article demonstrates an effective approach to developing and evaluating soil data sets for BTV development during any stage of the risk-assessment process. Whereas this article focuses on the most common metals associated with Type I errors (e.g., lead and arsenic), the process to estimate BTVs works for any organic or inorganic contaminants when sufficient data is available. The approach outlined in this article is intentionally conservative in nature to both increase regulatory acceptance and simplify the statistical steps needed for BTV estimation at earlier stages of the risk-assessment process.
Mental Functioning and Religiosity of Prisoners
Authors: Miałkowska-Kozaryna Milena , Miszewski Kamil 
Published: July 2024

Despite the important role religiosity plays in the resocialization of inmates, this research field lacks systematic reviews. The purpose of the study was to supply an account of mental functioning of prisoners viewed in the framework of their religiosity. The research included 124 individuals sentenced to twenty-five years of imprisonment. The research findings suggest that those offenders who claim to be believers significantly more often feature higher mental resilience (Mental Resilience Scale) and report more health-related issues, mainly somatic symptoms, anxiety and insomnia (GHQ-28). However, the analysis did not reveal any statistically significant relationship between religiosity and the level of anxiety (STAI) and the feel that penitentiary isolation is a stressful situation (the proprietary tool - Prison Isolation as a Stressful Situation). The study points to the role of faith for the mental functioning of offenders sentenced to long prison sentences and, as such, should be considered crucial to resocialization.
Gut Microbiota Dysbiosis in the Pathogenesis of Metabolic-dysfunction Associated Steatotic Liver Disease (MASLD)
Authors: Mir Gh Jeelani , Ashraf Nissar Ul 
Published: July 2024

:
Metabolic-dysfunction-associated steatotic liver disease (MASLD), previously referred
to as nonalcoholic fatty liver disease (NAFLD), affecting approximately 30% of the global population.
Projections suggest that MASLD incidence may rise by up to 56% over the next decade.
MASLD has become the fastest-growing cause of hepatocellular carcinoma (HCC) in the USA,
France, UK, and other regions worldwide. The prevalence of MASLD and MASLD-related liver
damage is expected to parallel the increasing rates of obesity and type 2 Diabetes Mellitus (T2DM)
globally. The factors contributing to MASLD development and its progression to metabolic-dysfunction-
associated steatohepatitis (MASH), fibrosis, cirrhosis, and HCC remain poorly understood.
Evidence from cell-based, animal-based, and human-subject studies suggests that insulin
resistance, endoplasmic reticulum stress, oxidative stress, impaired autophagy, genetics, epigenetics,
reduced immune surveillance, increased gut inflammation, and gut dysbiosis are crucial events
in MASLD pathogenesis. In recent years, dysregulation of gut microbiota has emerged as a potential
mechanism implicated in MASLD and MASLD-related hepatocarcinogenesis. This review
briefly outlines the mechanistic events significant for MASLD pathogenesis. Additionally, it offers
insight into dysregulated gut microbiota and its correlation with MASLD and MASLD-related liver
damage. Furthermore, it highlights pertinent questions for cell and microbiologists in the MASLD
research field. It underscores the necessity for identifying factors leading to gut microbiome
dysregulation in MASLD and MASH pathogenesis. Identifying these factors could aid in the development
of novel strategies for managing MASLD and MASLD-related liver damage.
The Relationship Between Symptom Change and Use of a Web-Based Self-Help Intervention for Parents of Children With Externalizing Behavior Disorders: Exploratory Study
Authors: Wähnke Laura , Dose Christina , Klemp Marie-Theres , Mühlenmeister Judith , Plück Julia , Döpfner Manfred 
Published: July 2024

Background
Web-based self-help (WASH) has been found to be effective in the treatment of child externalizing behavior disorders. However, research on the associations of caregivers’ use of WASH and symptom changes of child externalizing behaviors is lacking.

Objective
This study examined the longitudinal and reciprocal associations between the use of WASH by caregivers of children with externalizing behavior disorders and their children’s externalizing behavior symptoms.

Methods
Longitudinal data of 276 families from 2 intervention conditions of a randomized controlled trial (either unguided or supported by a therapist over the phone) were analyzed. Caregiver- and clinician-rated child externalizing behavior symptoms were assessed before (T1), in the middle (T2), and after the 6-month WASH intervention (T3). Additionally, 2 indicators of the caregivers’ use of the WASH intervention were considered: number of log-ins (frequency) and the percentage of completed material (intensity). Associations of caregivers’ use during early (T1-T2) and late (T2-T3) treatment with child externalizing behavior symptoms were analyzed using path analyses (structural equation modeling).

Results
Frequency and intensity of use were higher during the first 3 months than during the next 3 months of the intervention period. The number of log-ins at early treatment was significantly but weakly associated with caregiver-reported child externalizing behavior symptoms in the long term (T3). Moreover, caregiver-reported child externalizing severity at T2 predicted the number of log-ins in the late treatment. The results were not replicated when considering the percentage of completed material as a measure of use or when considering clinician ratings of child externalizing behavior symptoms.

Conclusions
The findings provide the first, albeit weak, evidence for longitudinal associations between caregivers’ use of WASH and improvements in caregiver-rated child externalizing behavior symptoms. However, as the associations were rather weak and could not be replicated across different rater perspectives and operationalizations of use, further research is needed to better understand these relations and their interplay with other putative influence factors (eg, quality of the implementation of the interventions, changes in parenting behaviors).

Trial Registration
German Clinical Trials Register DRKS00013456; https://www.drks.de/DRKS00013456

International Registered Report Identifier (IRRID)
RR2-10.1186/s12888-020-2481-0
Establishing Priorities for Improving Data Collection and Measurement of Mental Health and Well-Being of Adolescents With Special Educational Needs Within Nonmainstream Schools: Protocol for a Delphi Study
Authors: Jeffery Mairi C , Deighton Jessica , Lereya Suzet Tanya 
Published: July 2024

Background
There are more than 1.5 million children and young people in England with special educational needs (SEN), with over 160,000 young people in the United Kingdom attending a special school or alternative provision (AP) setting. Young people with SEN have been found to be at risk for poorer mental health and well-being than non-SEN peers. However, there is a range of both school-related and research challenges associated with identifying difficulties in a timely manner.

Objective
This Delphi study aims to determine a list of stakeholder priorities for improving school-based measurement of mental health and well-being among young people with SEN, at an aggregated level, within secondary special school or AP settings. A secondary objective is to inform the implementation of school-based well-being surveys, improve engagement in special schools or AP settings, and improve survey response rates among children and young people with SEN.

Methods
A mixed methods Delphi study will be conducted, including a scoping review and preliminary focus groups with school staff members and researchers to establish key issues. This will be followed by a 2-round Delphi survey to determine a list of stakeholder priorities for improving the measurement of mental health and well-being at an aggregate level within special schools and AP settings. A final stakeholder workshop will be held to discuss the findings. A list of recommendations will be drafted as a report for special schools and AP settings.

Results
The study has received ethical approval from the University College London Research Ethics Committee. The stage 1 scoping review has commenced. Recruitment for focus groups will begin in Autumn 2024. The first round of the Delphi survey will commence in early 2025, and the second round of the Delphi survey in the spring of 2025. The final workshop will commence in mid-2025 with final results expected in late 2025.

Conclusions
There is a need for clear recommendations for special schools and AP settings on priorities for improving the measurement of mental health and well-being problems among young people with SEN. There is also a need for recommendations to researchers implementing school-based well-being surveys, including the #BeeWell program, to enable them to improve their engagement in special schools and AP settings and ensure surveys are accessible.

International Registered Report Identifier (IRRID)
PRR1-10.2196/58610
A Microfinance Intervention With or Without Peer Support to Improve Mental Health Among Transgender and Nonbinary Adults (the Creating Access to Resources and Economic Support Study): Protocol for a Randomized Controlled Trial
Authors: Poteat Tonia C , Reisner Sari L , Wirtz Andrea L , Mayo-Wilson Larissa Jennings , Brown Carter , Kornbluh Wiley , Humphrey Ash , Perrin Nancy 
Published: July 2024

Background
Transgender and nonbinary (TNB) people experience economic and psychosocial inequities that make them more likely to be subject to financial and mental health harms exacerbated by the COVID-19 pandemic. Sustainable, multilevel interventions are needed to address these harms. The onset of the COVID-19 pandemic galvanized many TNB-led organizations to provide emergency financial and peer support for TNB people negatively impacted by the pandemic. However, the efficacy of these interventions has not been evaluated. The Creating Access to Resources and Economic Support (CARES) study seeks to assess the efficacy of feasible, acceptable, and community-derived interventions to reduce economic and psychological harms experienced by transgender people in the wake of the COVID-19 pandemic.

Objective
The study aims to (1) compare the efficacy of microgrants with peer mentoring with that of microgrants without peer mentoring in reducing psychological distress, (2) examine mechanisms by which microgrants with or without peer mentoring may impact psychological distress, and (3) explore participants’ intervention experiences and perceived efficacy.

Methods
We will enroll 360 TNB adults into an embedded, mixed methods, 3-arm, and 12-month randomized controlled trial. Participants will be randomized 1:1:1 to arm A (enhanced usual care), which will receive a single microgrant plus monthly financial literacy education, arm B (extended microgrants), which will receive enhanced usual care plus monthly microgrants, or arm C (peer mentoring), which will receive extended microgrants combined with peer mentoring. All intervention arms last for 6 months, and participants complete semiannual, web-based surveys at 0, 6, and 12 months as well as brief process measures at 3 and 6 months. A subset of 36 participants, 12 (33%) per arm, will complete longitudinal in-depth interviews at 3 and 9 months.

Results
Full recruitment began on January 8, 2024, and, as of July 26, 2024, a total of 138 participants have enrolled. Recruitment is expected to be completed no later than March 31, 2025, and the final study visit will take place in March 2026.

Conclusions
This national, web-based study will demonstrate whether an intervention tailored to reduce material hardship and improve peer support among TNB adults will reduce psychological distress. Its equitable, community-academic partnership will ensure the rapid dissemination of study findings.

Trial Registration
ClinicalTrials.gov NCT05971160; https://clinicaltrials.gov/study/NCT05971160

International Registered Report Identifier (IRRID)
DERR1-10.2196/63656
Karakter Makromorfologi dan Mikromorfologi Duku, Kokosan, Langsat dalam Penentuan Status Taksonomi pada Kategori Infraspesies
Authors: Hanum Laila , Kasiamdari Rina Sri , Santosa Santosa , Rugayah Rugayah 
Published: July 2024

Duku, kokosan dan langsat merupakan buah-buahan yang populer dan memiliki nilai ekonomi yang penting. Secara morfologi duku, kokosan dan langsatÂ hampir mirip satu sama lain sehingga menyulitkan dalam penentuan pada tingkat infraspesies bagi para pemulia tanaman. Berbagai pendekatan untuk penentuan morfologi ini telah banyak dilakukan. Tujuan penelitian ini menentukan status taksonomi duku, kokosan dan langsat pada ketegori infraspesies berdasarkan karakteritik makro dan mikromorfologi. Berbagai variasi duku, langsat dan kokosan dikoleksi dari beberapa pusat pertanaman di Indonesia, meliputi wilayah Sumatera, Jawa dan Kalimantan. Preparasi herbarium tumbuhan meliputi koleksi sampel, persiapan, penempelan dan identifikasi. Analisis morfologi menggunakan metode pengamatan dan deskripsi, pengukuran karakter morfologi dilakukan baik pada organ generatif dan vegetatif meliputi bunga, batang, biji dan buah, dan semua sampel didokumentasikan dengan menggunakan foto. Hasil penelitian ini menunjukkan ditemukan 29 variasi dari duku, kokosan, dan langsat yang terdiri dari 19 duku, 2 kokosan dan 8 langsat dari semua wilayah. Hasil karakterisasi makro dan mikromorfologi menunjukkan duku, kokosan, dan langsat dari berbagai daerah di Indonesia dapat dinyatakan duku, kokosan, dan langsat merupakan marga Lansium, untuk kategori jenis adalah L. domesticum Correa dan pada kategori infraspesies dapat dibagi menjadi dua group yaitu group duku dan group kokosan-langsat.
Kajian Etnobotani Peralatan Rumah Tangga Suku Anak Dalam di Taman Nasional Bukit Dua Belas Kabupaten Sarolangun, Jambi
Authors: Mairida Dwi , Hariyadi Bambang , Saudagar Fachruddin 
Published: July 2024

Suku Anak Dalam (SAD) merupakan salah satu kelompok masyarakat pedalaman hutan Jambi yang memiliki kemampuan dan kemandirian dalam membuat peralatan rumah tangga. Taman Nasional Bukit Duabelas (TNBD) merupakan kawasan pelestarian alam yang menyediakan potensi berbagai jenis flora bagi masyarakat SAD untuk memenuhi berbagai keperluan, salah satunya adalah untuk membuat kerajinan tradisional peralatan rumah tangga. Penelitian ini bertujuan untuk mengidentifikasi jenis-jenis peralatan rumah tangga yang digunakan SAD, mengkaji karakteristik dan cara pembuatan setiap peralatan, mengidentifikasi jenis-jenis tumbuhan yang dimanfaatkan, serta mengkaji perubahan penggunaan peralatan rumah tangga SAD. Pemilihan informan dilakukan menggunakan teknik snowball sampling. Data dikumpulkan dengan cara wawancara, observasi partisipasi aktif dan dokumentasi. Data yang diperoleh dianalisis secara deskriptif. Hasil penelitian menemukan 11 jenis peralatan rumah tangga yang biasa digunakan oleh SAD.Â Peralatan tersebut dibuat dengan memanfaatkan 21 spesies tumbuhan yang termasuk kedalam 12 famili.