bluuebunny/crossref_metadata_2025_split huggingface dataset:
The relation of student and class‐level characteristics to primary school students' autonomous reading motivation: a multi‐level approach
Authors: De Naeghel Jessie , Van Keer Hilde 
Published: May 2013

The aim of the present study is to examine by means of multi‐level modelling how student and class‐level characteristics relate to fifth‐grade students' recreational and academic autonomous reading motivation. On the student level, gender, native language and students' perception of home and peer involvements in reading activities are studied. On the class level, teachers' use of knowledge goals, the provision of real‐world interactions, students' opportunities to read self‐selected books and discuss reading materials with peers, teachers' reading aloud, the use of fiction and non‐fiction and support of a literacy coach are studied. Participants included 1,177 fifth‐graders and their 65 teachers. In line with the literature, girls report a higher autonomous reading motivation, and students' perception of home and peer involvements in reading activities is positively associated with their autonomous reading motivation. On the class level, only the additional support of a literacy coach significantly optimises students' autonomous reading motivation.Practitioner PointsWhat is already known about this topic

Autonomous reading motivation is associated with higher reading frequency, more reading engagement and better reading performance.
There is a declining trend in intrinsic reading motivation throughout children's educational career, setting in at the end of primary school.
Several student‐level characteristics on the one hand and class‐level characteristics on the other hand are positively related to reading motivation.What this paper adds

A more integrated empirical approach to reading promotion, addressing both student and class‐level correlates of autonomous reading motivation.
Adoption of multi‐level modelling in reading motivation research.Implications for practice and/or policy

Creating reading cultures among peers and at home benefits students' autonomous reading motivation.
Importance of reflection on reading and reading promotion in the approach and policy of the school.
What counts as reading? PIRLS, EastEnders and The Man on the Flying Trapeze
Authors: Maybin Janet 
Published: May 2013

AbstractAfter briefly reviewing how reading is conceptualised in the Progress in International Reading Literacy Study and the English National Curriculum, this article examines two unofficial reading activities in a class of 10–11‐year‐olds' to see how far these activities match up with the official definitions of reading, or whether they involve a different kind of interaction with text. Although the children's unofficial reading appears trivial, fleeting and fragmentary, analysis shows that they are applying, albeit in a rudimentary way, the comprehension skills of retrieval, inference, interpretation and evaluation promoted by the Progress in International Reading Literacy Study and the National Curriculum. These skills, however, are driven by children's emotional, critical and creative responses to the texts. The children's reading is more imaginative and dialogic than is possible within official curriculum activities; they interweave emotional and moral response with argument and critique in one example and respond humorously to poetic rhyme, rhythm and tone in another. These spontaneous reading activities, where children are active, animated and engaged, provide evidence of important dimensions of literacy which are not adequately addressed in official surveys and curriculum assessment.
Unexpected Consequences ofRicardian Expectations
Authors: Schlicht Ekkehart 
Published: May 2013

AbstractThe Ricardian equivalence thesis maintains that, given the time‐path of government spending, a change in taxation does not alter the set of feasible lifetime consumption plans of the households and affects neither the demand for commodities and services nor the rate of interest, provided the households act rationally. This note establishes that the very expectations the thesis proposes (‘Ricardian expectations') are invalidated if households act rationally. The divergence from Ricardian equivalence is traced to the omission of interest payments on public debt as part of the households' disposable income. The non‐equivalence is valid in a wide class of models.
Patient‐reported outcomes in bariatric surgery: a systematic review of standards of reporting
Authors: Coulman K. D. , Abdelrahman T. , Owen‐Smith A. , Andrews R. C. , Welbourn R. , Blazeby J. M. 
Published: May 2013

SummaryBariatric surgery is increasingly being used to treat severe obesity, but little is known about its impact on patient‐reported outcomes (PROs). For PRO data to influence practice, well‐designed and reported studies are required. A systematic review identified prospective bariatric surgery studies that used validated PRO measures. Risk of bias in randomized controlled trials (RCTs) was assessed, and papers were examined for reporting of (i) who completed PRO measures; (ii) missing PRO data and (iii) clinical interpretation of PRO data. Studies meeting all criteria were classified as robust. Eighty‐six studies were identified. Of the eight RCTs, risk of bias was high in one and unclear in seven. Sixty‐eight different PRO measures were identified, with the Short Form (SF)‐36 questionnaire most commonly used. Forty‐one (48%) studies explicitly stated measures were completed by patients, 63 (73%) documented missing PRO data and 50 (58%) interpreted PRO data clinically. Twenty‐six (30%) met all criteria. Although many bariatric surgery studies assess PROs, study design and reporting is often poor, limiting data interpretation and synthesis. Well‐designed studies that include agreed PRO measures are needed with reporting to include integration with clinical outcomes to inform practice.
The effect of strabismus on object detection in the ring scotoma of a monocular bioptic telescope
Authors: Doherty Amy L , Bowers Alex R , Luo Gang , Peli Eli 
Published: May 2013

AbstractPurposePeople with reduced visual acuity are permitted to drive with the aid of bioptic telescopes in the USA, the Netherlands, and Canada. When viewing through a monocular bioptic telescope, suppression of the deviating eye in strabismus may reduce the ability of the non‐telescope eye to detect objects whose images fall in the ring scotoma area of the telescope eye, which could impair detection of traffic‐relevant events. This ability to detect stimuli in the ring scotoma area was compared for strabismic and non‐strabismic patients.MethodsTen strabismic and six non‐strabismic patients with bilaterally reduced visual acuity (0.30–1.0 logMAR, 6/12 to 6/60) participated. A dichoptic perimeter presented stimuli to the fellow (non telescope) eye in the area of the ring scotoma under binocular viewing. Fellow‐eye detection rates were determined with and without a bioptic, on uniform and patterned backgrounds, while performing passive (viewing a cross) and active (reading letters) fixation tasks.ResultsAll strabismic patients were found to have anomalous retinal correspondence. Both non‐strabismic and strabismic patients had lower fellow‐eye detection rates on patterned than on uniform backgrounds, and while performing the active task. In addition, strabismic patients had lower detection with than without the bioptic on the patterned background. They also had a larger decrease in detection from the uniform to the patterned background than non‐strabismic patients (26% vs 8%). Depending on the angle and direction of the deviation relative to the stimulus side, strabismus either increased or decreased fellow‐eye stimulus eccentricity on the retina. Larger detection rate reductions between the uniform and patterned backgrounds were associated with more eccentric stimulus locations (ρ = 0.61, p = 0.013).ConclusionsBoth strabismic patients and non‐strabismic patients were able to detect stimuli with the fellow eye in the ring scotoma area, demonstrating successful bi‐ocular multiplexing. However, strabismic patients generally had a greater reduction in detection performance from the uniform to the patterned background than non‐strabismic patients, which was accounted for in part by differences in stimulus eccentricities on the retina (that varied with the angle and direction of the strabismus). However, a study with a larger sample, including participants with strabismus and normal retinal correspondence, is needed before our findings can be generalized.
Moderate water stress causes different stomatal and non‐stomatal changes in the photosynthetic functioning of Phaseolus vulgaris L. genotypes
Authors: Ramalho J. C. , Zlatev Z. S. , Leitão A. E. , Pais I. P. , Fortunato A. S. , Lidon F. C. 
Published: May 2013

AbstractThe impact of moderate water deficit on the photosynthetic apparatus of three Phaseolus vulgaris L. cultivars, Plovdiv 10 (P10), Dobrudjanski Ran (DR) and Prelom (Prel), was investigated. Water shortage had less impact on leaf hydration, RWC (predawn and midday) and predawn water potential in Prel. RWC and Ψp were more reduced in P10, while there was no osmotic adjustment in any cultivar. Although drought drastically reduced stomatal opening in P10 and DR, reduced Amax indicated non‐stomatal limitations that contributed to the negligible Pn. These limitations were on potential thylakoid electron transport rates of PSI and II, pointing to photosystem functioning as a major limiting step in photosynthesis. This agrees with decreases in actual photochemical efficiency of PSII (Fv′/Fm′), quantum yield of photosynthetic non‐cyclic electron transport (ϕe) and energy‐driven photochemical events (qP), although the impact on these parameters would also include down‐regulation processes. When compared to DR, Prel retained a higher functional state of the photosynthetic machinery, justifying reduced need for photoprotective mechanisms (non‐photochemical quenching, zeaxanthin, lutein, β‐carotene) and maintenance of the balance between energy capture and dissipative pigments. The highest increases in fructose, glucose, arabinose and sorbitol in Prel might be related to tolerance to a lower oxidative state. All cultivars had reduced Amax due to daytime stomatal closure in well‐watered conditions. Under moderate drought, Prel had highest tolerance, higher leaf hydration and maintenance of important photochemical use of energy. However, water shortage caused appreciable non‐stomatal limitations to photosynthesis linked to regulation/imbalance at the metabolic level (and growth) in all cultivars. This included damage, as reflected in decreased potential photosystem functioning, pointing to higher sensitivity of photosynthesis to drought than is commonly assumed.
Copper toxicity in Chinese cabbage is not influenced by plant sulphur status, but affects sulphur metabolism‐related gene expression and the suggested regulatory metabolites
Authors: Shahbaz M. , Stuiver C. E. E. , Posthumus F. S. , Parmar S. , Hawkesford M. J. , De Kok L. J. 
Published: May 2013

AbstractThe toxicity of high copper (Cu) concentrations in the root environment of Chinese cabbage (Brassica pekinensis) was little influenced by the sulphur nutritional status of the plant. However, Cu toxicity removed the correlation between sulphur metabolism‐related gene expression and the suggested regulatory metabolites. At high tissue Cu levels, there was no relation between sulphur metabolite levels viz. total sulphur, sulphate and water‐soluble non‐protein thiols, and the expression and activity of sulphate transporters and expression of APS reductase under sulphate‐sufficient or‐deprived conditions, in the presence or absence of H2S. This indicated that the regulatory signal transduction pathway of sulphate transporters was overruled or by‐passed upon exposure to elevated Cu concentrations.
Location Based Social Networks – Definition, Current State of the Art and Research Agenda
Authors: Roick Oliver , Heuser Susanne 
Published: May 2013

AbstractThe growing penetration of GPS equipped smartphones allowing users to constantly share geographic information on their current whereabouts has led the way to an augmentation of existing Social Network Sites with location‐based features or the creation of new ones exclusively around geographic information. Within these Location Based Social Networks vast amounts of geographic information are allocated, which attracted the attention of researchers with various scientific backgrounds. This article presents a comprehensive definition of this special type of Social Network Site and an overview of research activities, which are currently conducted using the data. Finally, a research agenda for GIScience is drawn from existing research directions.
Growth factor release from platelet concentrates: analytic quantification and characterization for clinical applications
Authors: Durante C. , Agostini F. , Abbruzzese L. , T. Toffola R. , Zanolin S. , Suine C. , Mazzucato M. 
Published: May 2013

Background and ObjectivesClinical use of plasma rich in growth factors requires biochemical product control. We aimed to measure and modulate concentrations of growth factors in solutions deriving from platelet apheresis or whole blood.Materials and MethodsGrowth factor concentrations were measured 5’, 10’, 20’, 30’, 60’ after CaCl2 was added at 40°C to platelet‐apheresis products (n = 39) or after 60’ in platelet concentrates from whole blood (n = 13). Growth factor release was also obtained in platelet apheresis a) by incubation at 22°C or 40°C for 10’ or 30’ (n = 4); b) by repeated freeze–thaw (n = 9).ResultsFibroblast growth factor (FGF), platelet‐derived growth factor (PDGF) isoforms AA and AB and transforming growth factor beta (TGF‐β) concentrations (pg/109 plt) were 25–60% higher in growth factors solutions from whole blood compared to platelet apheresis. Vascular endothelial growth factor (VEGF), TGF‐β and PDGF isoforms were released early (5–10’) during incubation: TGF‐β concentration increased also at 30’. FGF and epidermal growth factor (EGF) were released only after 30’. Incubation at 40°C/10’ increased VEGF (+70%) and decreased EGF (−30%) and PDGF‐BB (−50%) versus 22°C/30’. Shock significantly increased TGF‐β (1·6‐fold), EGF (1·5‐fold), FGF (4·5‐fold) and lowered PDGF isoforms (0·2‐ to 0·5‐fold) versus prolonged incubation at 40°C.ConclusionPlatelets from platelet apheresis and whole‐blood release all investigated growth factors. The release can be regulated controlling incubation time and/or temperature and performing cell lysis.
Nuclear imaging of the breast: Translating achievements in instrumentation into clinical use
Authors: Hruska Carrie B. , O'Connor Michael K. 
Published: May 2013

Approaches to imaging the breast with nuclear medicine and/or molecular imaging methods have been under investigation since the late 1980s when a technique called scintimammography was first introduced. This review charts the progress of nuclear imaging of the breast over the last 20 years, covering the development of newer techniques such as breast specific gamma imaging, molecular breast imaging, and positron emission mammography. Key issues critical to the adoption of these technologies in the clinical environment are discussed, including the current status of clinical studies, the efforts at reducing the radiation dose from procedures associated with these technologies, and the relevant radiopharmaceuticals that are available or under development. The necessary steps required to move these technologies from bench to bedside are also discussed.
Divergent Picornavirus from a Turkey with Gastrointestinal Disease
Authors: Ng Terry Fei Fan , Cheung Andrew K. , Wong Walt , Lager Kelly M. , Kondov Nikola O. , Cha Yunhee , Murphy Duane A. , Pogranichniy Roman M. , Delwart Eric 
Published: May 2013

ABSTRACT

A novel picornavirus, turkey avisivirus (TuASV), was identified from the feces of turkeys (
Meleagris gallopavo
) with gastrointestinal disease from a farm in Indiana. Its genome organization is as follows: 5′ untranslated region (UTR)
IRES-II
[VP0, VP3, VP1, 2A, 2B, 2C, 3A, 3B, 3C
pro
, 3D
pol
] 3′ UTR-poly(A). TuASV shares only 34% (P1), 36% (P2), and 35% (P3) amino acid identities with avihepatoviruses, indicating that it potentially represents a novel picornavirus genus.
Genome Sequences of Two Klebsiella pneumoniae Isolates from Different Geographical Regions, Argentina (Strain JHCK1) and the United States (Strain VA360)
Authors: Xie Gary , Ramirez Maria S. , Marshall Steven H. , Hujer Kristine M. , Lo Chien-Chi , Johnson Shannon , Li Po-E , Davenport Karen , Endimiani Andrea , Bonomo Robert A. , Tolmasky Marcelo E. , Chain Patrick S. G. 
Published: May 2013

ABSTRACT

We report the sequences of two
Klebsiella pneumoniae
clinical isolates, strains JHCK1 and VA360, from a newborn with meningitis in Buenos Aires, Argentina, and from a tertiary care medical center in Cleveland, OH, respectively. Both isolates contain one chromosome and at least five plasmids; isolate VA360 contains the
Klebsiella pneumoniae
carbapenemase (KPC) gene.
Complete Genome Sequence of a Chinese Strain of “
Candidatus
Liberibacter asiaticus”
Authors: Lin Hong , Han Cliff S. , Liu Binghao , Lou Binghai , Bai Xianjin , Deng Chongling , Civerolo Edwin L. , Gupta Goutam 
Published: May 2013

ABSTRACT

We report here the complete genome sequence of “
Candidatus
Liberibacter asiaticus” (strain Guangxi-1). The 1,268,237-bp genome with a 36.5% G+C content comprises 1,141 open reading frames, 44 tRNAs, and 3 complete rRNAs in a circular chromosome.
Genome Sequence of Halanaerobium saccharolyticum subsp.
saccharolyticum
Strain DSM 6643
T
, a Halophilic Hydrogen-Producing Bacterium
Authors: Kivistö Anniina , Larjo Antti , Ciranna Alessandro , Santala Ville , Roos Christophe , Karp Matti 
Published: May 2013

ABSTRACT

Halanaerobium saccharolyticum
is a halophilic anaerobic fermentative bacterium capable of producing hydrogen, a potential future energy carrier molecule. The high-quality draft genome of
H. saccharolyticum
subsp.
saccharolyticum
strain DSM 6643
T
consists of 24 contigs for 2,873,865 bp with a G+C content of 32.3%.
Complete Genome Sequence of the Probiotic Bifidobacterium thermophilum Strain RBL67
Authors: Jans Christoph , Lacroix Christophe , Follador Rainer , Stevens Marc J. A. 
Published: May 2013

ABSTRACT

Bifidobacterium thermophilum
RBL67, an isolate from infant feces, exhibits bacteriocin-like antimicrobial activity against
Listeria
spp. and
Salmonella
spp. and protects HT29-MTX cells against
Salmonella
infection. Here, the complete genome sequence of the probiotic
B. thermophilum
strain RBL67 is presented.
Draft Genome Sequence of Bacillus stratosphericus LAMA 585, Isolated from the Atlantic Deep Sea
Authors: Lima André Oliveira de Souza , Cabral Alencar , Andreote Fernando Dini , Cavalett Angélica , Pessatti Marcos Luiz , Dini-Andreote Francisco , da Silva Marcus Adonai Castro 
Published: May 2013

ABSTRACT

Bacillus stratosphericus
LAMA 585 was isolated from the Mid-Atlantic-Ridge seafloor (5,500-m depth). This bacterium presents the capacity for cellulase, xylanase, and lipase production when growing aerobically in marine-broth media. Genes involved in the tolerance of oligotrophic and extreme conditions and prospection of biotechnological products were annotated in the draft genome (3.7 Mb).
Hardware-Assisted Cooperative Integration of Wear-Leveling and Salvaging for Phase Change Memory
Authors: Jiang Lei , Du Yu , Zhao Bo , Zhang Youtao , Childers Bruce R. , Yang Jun 
Published: May 2013

Phase Change Memory (PCM) has recently emerged as a promising memory technology. However, PCM’s limited write endurance restricts its immediate use as a replacement for DRAM. To extend the lifetime of PCM chips, wear-leveling and salvaging techniques have been proposed. Wear-leveling balances write operations across different PCM regions while salvaging extends the duty cycle and provides graceful degradation for a nonnegligible number of failures.
Current wear-leveling and salvaging schemes have not been designed and integrated to work cooperatively to achieve the best PCM device lifetime. In particular, a noncontiguous PCM space generated from salvaging complicates wear-leveling and incurs large overhead. In this article, we propose LLS, a Line-Level mapping and Salvaging design. By allocating a dynamic portion of total space in a PCM device as backup space, and mapping failed lines to backup PCM, LLS constructs a contiguous PCM space and masks lower-level failures from the OS and applications. LLS integrates wear-leveling and salvaging and copes well with modern OSes. Our experimental results show that LLS achieves 31% longer lifetime than the state-of-the-art. It has negligible hardware cost and performance overhead.
PI3K/mTOR Inhibitor PF-04691502 Antitumor Activity Is Enhanced with Induction of Wild-Type TP53 in Human Xenograft and Murine Knockout Models of Head and Neck Cancer
Authors: Herzog Amanda , Bian Yansong , Vander Broek Robert , Hall Bradford , Coupar Jamie , Cheng Hui , Sowers Anastasia L. , Cook John D. , Mitchell James B. , Chen Zhong , Kulkarni Ashok B. , Van Waes Carter 
Published: May 2013

AbstractPurpose: Phosphoinositide 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) pathway activation is often associated with altered expression or mutations of PIK3CA, TP53/p73, PTEN, and TGF-β receptors (TGFBR) in head and neck squamous cell carcinomas (HNSCC). However, little is known about how these alterations affect response to PI3K/mTOR–targeted agents.Experimental Design: In this preclinical study, PI3K/Akt/mTOR signaling was characterized in nine HNSCC (UM-SCC) cell lines and human oral keratinocytes. We investigated the molecular and anticancer effects of dual PI3K/mTOR inhibitor PF-04691502(PF-502) in UM-SCC expressing PIK3CA with decreased wild-type TP53, mutant TP53−/+ mutantTGFBR2, and in HNSCC of a conditional Pten/Tgfbr1 double knockout mouse model displaying PI3K/Akt/mTOR activation.Results: UM-SCC showed increased PIK3CA expression and Akt/mTOR activation, and PF-502 inhibited PI3K/mTORC1/2 targets. In human HNSCC expressing PIK3CA and decreased wtTP53 and p73, PF-502 reciprocally enhanced TP53/p73 expression and growth inhibition, which was partially reversible by p53 inhibitor pifithrin-α. Most UM-SCC with wtTP53 exhibited a lower IC50 than those with mtTP53 status. PF-502 blocked growth in G0–G1 and increased apoptotic sub-G0 DNA. PF-502 suppressed tumorigenesis and showed combinatorial activity with radiation in a wild-type TP53 UM-SCC xenograft model. PF-502 also significantly delayed HNSCC tumorigenesis and prolonged survival of Pten/Tgfbr1-deficient mice. Significant inhibition of p-Akt, p-4EBP1, p-S6, and Ki67, as well as increased p53 and TUNEL were observed in tumor specimens.Conclusions: PI3K-mTOR inhibition can enhance TP53/p73 expression and significantly inhibit tumor growth alone or when combined with radiation in HNSCC with wild-type TP53. PIK3CA, TP53/p73, PTEN, and TGF-β alterations are potential modifiers of response and merit investigation in future clinical trials with PI3K-mTOR inhibitors. Clin Cancer Res; 19(14); 3808–19. ©2013 AACR.