bluuebunny/crossref_metadata_2025_split huggingface dataset:
Psychological and Communication Barriers in Receiving Medical Care for Older Adults
Authors: Chukavina A. V. , Almasud R. , Viskochkov V. S. , Tufilin D. S. , Runikhina N. K. , Tkacheva O. N. , Kobyakova O. S. 
Published: February 2025

BACKGROUND. According to the United Nations, by 2050, it is expected that every sixth inhabitant of our planet will have crossed the threshold of 65 years. This indicates an urgent need to identify the main barriers that arise when providing medical care in order to improve the process of organizing medical services for people over working age.AIM. To study the characteristics of psychological and communication barriers (problems in defining the model of the doctor-patient relationship) in the Russian Federation when providing medical services to people over the working age, with the aim of developing recommendations based on these findings to eliminate these obstacles.MATERIALS AND METHODS. In this study, a questionnaire was used, consisting of three blocks and 89 questions. The data were analyzed using Statistica 10, Stata, and R-Studio programs. The Pearson’s chi-square test was used to compare categorical variable distributions. A generalized linear model was used to test the impact of individual characteristics on the outcome variable. The Mann-Whitney U and Kruskal-Wallis tests were used to analyze differences between samples with abnormal distributions.RESULTS. A total of 3,942 individuals participated in the survey. Among the study participants, the most prevalent psychological barrier to engaging with the healthcare system was fear of visiting a medical facility associated with the potential for detecting new illnesses or worse outcomes (66.6%). Approximately half of respondents indicated that this could serve as a reason for not seeking medical attention (52%). The most commonly reported communication barriers included the need for assistance in understanding doctor’s prescriptions (27.7%), difficulty understanding doctor’s speech due to hearing problems (18.5%), the frequent use of incomprehensible terminology by doctors (25.7%), and approaching problems in a formal manner or not delving deeply enough (24%)CONCLUSION. The research conducted will allow us to make managerial and organizational decisions in a more purposeful and reasonable manner, in order to create a trustworthy environment, improve the quality of doctorpatient communication, and provide necessary psychological support during medical care for people over working age.
Competencias y liderazgo para la gestión organizacional en la era digital
Authors: Serrato Marco 
Published: February 2025

El Dr. Marco Serrato, Vicepresidente Asociado de la Empresa de Aprendizaje de la Universidad Estatal de Arizona (ASU), conversó con la Revista de Ciencias Empresariales sobre habilidades clave y principales desafíos de aprendizaje que enfrentan las organizaciones, las personas y los líderes en el contexto actual.

Abstract
Doctor Marco Serrato, Associate Vice President of the Learning Enterprise at Arizona State University (ASU), spoke to the Journal of Business Studies about key skills and major learning challenges facing organisations, individuals and leaders in today's context.
A Long-term Study of Mrk 50: Appearance and Disappearance of Soft Excess
Authors: Layek Narendranath , Nandi Prantik , Naik Sachindra , Jana Arghajit 
Published: February 2025

Abstract
We present an extensive temporal and spectral study of the Seyfert 1 AGN Mrk 50 using 15 yr (2007–2022) of multiwavelength observations from XMM-Newton, Swift, and NuSTAR for the first time. From the timing analysis, we found that the source exhibited variability of ∼20% during the 2007 observation, which reduced to below 10% in the subsequent observations and became nonvariable in the observations from 2010 onward. From the spectral study, we found that the spectra are nearly featureless. Nondetection of absorption in the low-energy domain during the 15 yr of observation infers the absence of obscuration around the central engine, rendering the nucleus a “bare” type. A prominent soft X-ray excess below 2 keV was detected in the source spectrum during the observations between 2007 and 2010, which vanished during the later observations. To describe the nature of the soft excess, we use two physical models, such as warm Comptonization and blurred reflection from the ionized accretion disk. Both of the physical models explain the nature and origin of the soft excess in this source. Our analysis found that Mrk 50 accretes at a sub-Eddington accretion rate (λ
Edd = 0.13–0.02) during all of the observations used in this work.
Use of Continuous Glucose Monitoring in Skilled Nursing Facilities: Strategies for Managing Implementation
Authors: Keers Lucy G. , Brodeur Michael R. , Tran Lara 
Published: February 2025

Purpose
Continuous glucose monitoring (CGM) devices are increasingly used by older adults. Although these devices offer several advantages over traditional techniques, such as fingerstick capillary blood glucose, the current article discusses the impact and benefits of CGMs in the context of older adults in skilled nursing facilities (SNFs) and explores ways to improve and manage their use through the collaboration of an interprofessional team.

Method
Current evidence and guidance on implementing CGM devices in SNFs is reviewed.

Results
Current strategies for the successful and safe use of CGM devices in SNFs include staff and patient education, close monitoring, operational workflow, and interprofessional collaboration.

Conclusion

To manage patients with diabetes in SNFs, an interactive, multidisciplinary, and multifaceted approach is needed. Larger studies on the management of CGM devices in SNFs are required. [
Journal of Gerontological Nursing, 51
(3), 7–12.]
Oralidade, gêneros orais e formação de professores:
Authors: Bueno Luzia , Rodrigues de Sousa Fabiana , Baptista Wesley 
Published: February 2025

Este artigo tem como objetivo refletir sobre o trabalho com a oralidade e os gêneros orais na formação de professores/as. Para isso, apoiando-nos em quadros teóricos-metodológicos que ressaltam o papel da linguagem, da pronúncia coletiva do mundo e da educação na formação humana, visando à construção de uma sociedade com consciência crítica e transformadora, analisamos grades curriculares de cursos de graduação para tratarmos da formação inicial e iniciativas de formação continuada. Os resultados indicam que os documentos oficiais ainda não destacam a importância da oralidade e dos gêneros orais na formação de professores/as, todavia há iniciativas que colocam os/as docentes em diálogo apreendendo-os como protagonistas de fato e de direito das decisões sobre a organização de seu trabalho. Tais iniciativas têm condições de superar as limitações impostas pelas prescrições iniciais ao proporem novos caminhos da sala de aula para as ruas da cidade.
Furosemide’s Preventative Role in Contrast-Induced Nephropathy among ST-Segment Elevation Myocardial Infarction Patients undergoing Percutaneous Coronary Intervention
Authors: Ariafar Mostafa , Ghorbani Parvin , Seyedian Seyed Masoud , Ahamdi Farzaneh , Sabetnia Leila , Farhadi Elham 
Published: February 2025

Background:
ST-elevation myocardial infarction (STEMI) is regarded as a risk factor for contrast-induced nephropathy (CIN). Numerous studies have explored preventive measures for CIN such as the use of diuretics. However, the specific impact of diuretics in averting nephropathy remains uncertain. We investigated whether post-treatment with furosemide decreases CIN risk.

Materials and Methods:
We designed a clinical trial and included 234 patients with STEMI undergoing primary percutaneous coronary intervention (PCI). Patients were divided into two groups: Group I (furosemide 0.5 mg/kg) and Group II (control). Serum creatinine and blood urea nitrogen (BUN) were measured pre- and post-surgery. CIN was described as more than either 25% or 0.5 mg/dL induction in serum creatinine from the baseline in 24 h and 72 h post-PCI.

Results:
CIN occurred in 33 patients (14.1%) in 24 h and 35 patients (14.9%) in 72 h. CIN incidence was not significantly different between both groups. However, BUN was significantly higher in the furosemide group (P < 0.05). Most patients in the furosemide group were men and smokers compared to the control group.

Conclusion:
A combination of low-dose furosemide plus standard hydration was not correlated with lower CIN incidence in STEMI patients who are candidates for primary PCI compared to standard hydration only. Further studies with a larger sample size in the future are needed to better understand the effects of this combination.
The in Vitro Antimicrobial Effect of Ethanolic Extracts of Aloe Vera on the H-pylori and Inhibitory Effect of Secondary Metabolites of Aloe Vera by Molecular Docking
Authors: Farajnabi Roghayeh , Hojjati Bonab Zahra , Shagayegh Neda 
Published: February 2025

Background:
Helicobacter pylori is a Gram negative bacterium in the human stomach. Considering the side effects of the drug regimen and the prevalence of antibiotic resistance, in this project, the antimicrobial effect of aloe vera extracts on Helicobacter pylori was tested.

Materials and Methods:
Evaluation of the antimicrobial effect of aloe vera extract on Helicobacter pylori was done using diffusion methods in agar, and the diameter of the nongrowth halo was measured. The molecular interaction between the active ingredients of aloe vera and urease enzyme was investigated with Mulgroo Virtual Docker (MVD) software.

Results:
The diameter of the halo of no growth at a concentration of 1000 mg/ml in aloe vera was 19 mm, and the maximum diameter of no growth was observed in the ethanolic extract.

Conclusion:
According to our results, the ethanolic extract of aloe vera can be suggested as a good option as an antimicrobial supplement for Helicobacter pylori.
Predictive value of microRNA-122 in obesity and metabolic syndrome
Authors: Abdelhafez Aisha H. , Abdel Fattah Wafaa M. , Seliem Nora , Mohamed Eman F. 
Published: February 2025

Background and aim
Metabolic syndrome (MetS) is a collection of metabolic dysregulations such as hypertension, insulin resistance, atherogenic dyslipidemia, and central obesity. MicroRNA-122 (miR-122) was the first of the many circulating miRNAs linked to metabolic diseases and obesity. MiR-122 is a liver-enriched miRNA that influences lipid and cholesterol metabolism. This study aims to evaluate the miR-122 function in the obesity’s pathogenesis and to assess the possible association of miRNA-122 with MetS in obese patients.

Patients and methods
The study included 50 Egyptian individuals (20 healthy persons as control, 15 obese patients without MetS, and 15 obese patients with MetS). The levels of miR-122 were validated using quantitative reverse transcription real-time polymerase chain reaction tests.

Results
Serum miR-122 demonstrated a highly significant increase in obese patients collectively compared with the control (P<0.001). Moreover, miR-122 demonstrated upregulation expression in obese cases having MetS compared with controls and the obese without MetS. There were statistically significant strong positive correlations between miR-122 expression and BMI, waist circumference, blood pressure, markers of dysglycemia, and dyslipidemia. Also, there were negative correlations with high-density lipoprotein (all having P=<0.001).

Conclusion
MiR-122 could be a valuable biomarker of obesity’s pathogenesis and MetS in obese patients.
Quality of life of mothers of children with autistic disorder
Authors: Hamed Amira M.M. , Aladawy Mohammed A. , Gaad Eman F. , Khodery Aml R.A. 
Published: February 2025

Background and aim
Quality of life (QoL) assessment for families of autistic children has become a crucial research topic. Purpose of this study was to evaluate the QoL of mothers of children diagnosed with autistic disorder.

Patients and methods
This prospective study included 50 children diagnosed with autistic disorder according to autism spectrum disorder (ASD) diagnostic criteria by DSM-5, aged from 2 to 16 years, in addition to their mothers.

Results
This study found that 80% of the mothers in the study reported low QoL and that mothers of children with severe ASD rated their QoL worse than mothers of children with mild and moderate ASD. The degree of QoL affection was more in the subgroup with attention deficit hyperactivity disorder comorbidity. Also, the QoL of mothers is affected by the level of intelligence quotient impairment in their children, with the lowest mean QoL scores in mothers of severely mentally defective children. By comparing between QoL scores before and after child behavioural therapy, the results showed that the post-test QoL scores had increased significantly.

Conclusion
QoL was rated low in mothers whose children had autistic disorder. Mothers’ QoL was shown to be substantially related to the degree of ASD symptoms among their children. However, giving behavioral treatment sessions to those children was linked to a significant increase in the mothers’ QoL.
Value of middle cerebral artery and umbilical artery Doppler indices in preeclamptic patients and their correlation with outcomes
Authors: Mustafa Faisal A. , Mohamed Duaa H. , Ahmed Yasser A.A. 
Published: February 2025

Background and aim
Preeclampsia is an important factor contributing to prenatal prematurity, intrauterine growth retardation, and the death of mothers. It is clinically evident after 20 weeks of gestation and impacts ∼5–10% of pregnancies. This study aimed to compare middle cerebral artery (MCA) and umbilical artery (UA) Doppler indices in preeclampsia patients versus normotensive pregnant ladies and to correlate the effect of MCA and UA Doppler indices with outcomes intrauterine growth retardation, perinatal death, and prematurity.

Patients and methods
This prospective case–control study was conducted on 100 cases divided into two groups: 50 women who have the diagnosis of preeclampsia according to recent guidelines of the International Society for the Investigation of Hypertension in Pregnancy and 50 normotensive pregnant ladies as a control group in Al-Azhar University Hospital in a period starting from July 2021 to July 2023.

Results
The best diagnostic accuracy for the prediction of adverse outcomes of preeclampsia was noticed with UA resistive index [90% with an area under the curve (AUC) was 0.90] followed by UA pulsatility (78% with AUC was 0.80) and MCA resistive index (76% with AUC was 0.75). Also, the UA systolic diastolic ratio had 70% overall accuracy for the prediction of preeclampsia with the AUC was 0.74.

Conclusion
UA and MCA Doppler indices were worse in preeclamptic versus nonpreeclamptic ladies. Worse Doppler indices were correlated with a greater incidence of adverse neonatal findings and were predictive of preeclampsia.
Comparison between hysterosalpingography and three-dimensional sonohysterography in infertile women
Authors: Muhammad Muhammad A.S. , Fathy Medhat K. , Salem Omar M.M. 
Published: February 2025

Background and aim
Infertility is characterized as the failure to achieve conception naturally following 1 year of consistent sexual activity that is unprotected. This study aimed to compare three-dimensional sonohysterography (3D-SIS) versus radiograph hysterosalpingography (HSG) in the evaluation of infertile ladies.

Patients and methods
This cross-section study was performed on 50 infertile women who underwent 3D-SIS and standard HSG between 7th and 12th day of their menstrual cycles from patients visiting the gynecological clinic at Al-Azhar University outpatient facility in Assiut.

Results
Regarding tubal patency and tubal blocking in HSG and 3D-SIS, there were highly significant differences (P<0.001). Regarding intrauterine lesions in HSG and 3D-SIS, there were highly significant differences which represent that 3D-SIS was more accurate and specific than HSG (P<0.001). Visual analog scale score pain value, HSG represents 48% mild pain, 34% moderate, and 18% severe pain, while; 3D-SIS represents 70% mild pain, 28% moderate, and 2% severe pain. Regarding pain value in HSG and 3D-SIS, there were highly significant differences, which represents that pain was tolerable in 3D-SIS other than HSG (P<0.001).

Conclusion
3D-SIS provides the best outcomes alternative to HSG in infertile women regarding tubal patency, intrauterine lesion, and pain. The elevated sensitivity of HSG has rendered it an effective screening instrument for intrauterine anomalies.
Incidence and risk factors of pulmonary embolism in cancer patients
Authors: Mohammed Omar G.M. , Abd-Allah Hamdy M. , Gabr Adel G.M. , Abdalla Hytham , Mohammed Hossam A.E.-M. 
Published: February 2025

Background and aim
Pulmonary embolism (PE) is a critical complication significantly more prevalent in cancer patients due to factors such as hypercoagulability, immobility, and chemotherapy. The incidence and risk factors vary with cancer type, treatment, and patient demographics, necessitating a detailed investigation to enhance management and outcomes.
This study aimed to evaluate the incidence and identify risk factors of PE in cancer patients, focusing on demographics, clinical characteristics, and outcomes to inform prevention strategies.

Patients and methods
Conducted at the South Egypt Cancer Institute, this study combined retrospective and prospective analyses of cancer patients admitted over a year. It involved history taking, clinical and laboratory evaluations, and radiological investigations to identify PE cases and associated risk factors.

Results
Among 294 patients, 91 were diagnosed with PE. Significant risk factors included a history of surgery (62.6% in the PE group vs. 34.9% in non-PE) and previous deep vein thrombosis (82.4% vs. 2.9%). The PE group showed a higher mean international normalized ratio and D-dimer levels. Breast, thyroid, and lung cancers were the most associated with PE. Anticoagulant therapy predominantly involved low-molecular-weight heparin.

Conclusion
Cancer patients, particularly those with a history of surgery or deep vein thrombosis, exhibit a higher risk of PE, with specific cancer types showing greater association. These findings underscore the necessity for vigilant PE risk assessment and management in cancer patients, advocating for further research to validate these observations.
Sclerotherapy injection in management of aneurysmal bone cyst
Authors: Abdallah Ahmed Ehab A. , Khashaba Ahmed S.I. , Elwany Hasan Abdallah M. 
Published: February 2025

Background and aim
Aneurysmal bone cyst (ABC) is a benign bone lesion of childhood and adolescence. It can be locally aggressive, with risk of fracture. Management is controversial. The study aimed to assess radiologically the healing of ABC together with assessment of Patient’s functional and physiological activities in response to Polidocanol with adjuvant bone marrow injection.

Patients and methods
This prospective case–series study was conducted on 20 patients with ABCs of long bones (femur, tibia, and humerus) that were managed by sclerotherapy (polidocanol) injection at Al-Azhar University Hospitals, Department of Orthopedics and Trauma Surgery, between 2022 and 2023.

Results
The mean initial visual analogue scale (VAS) for pain was 6.2±1.3. Before the fourth injection, the mean VAS declined to 1.9±1.4. The pain level continued to decline from 1 to 12 months after the fourth injection. At 12 months following the fourth injection, the mean VAS for pain was 0.3±0.48. Regarding postoperative complications, one patient developed nausea and vomiting, and two patients reported ecchymosis at the injection site.

Conclusion
We assessed the radiological healing of ABC in response to Polidocanol injection, together with an assessment of functional and physiological activities. Percutaneous intervention is the treatment of choice now in the management of ABC as it is effective, less invasive, and more cosmetically with no donor site morbidity as in conventional open intervention.
Risks of Malignancy among 11,204 Patients with Endometrial Polyp: A Systematic Review and Meta-analysis
Authors: Al-Rayes Sarah , Mohamed Mariam , Suarthana Eva , Kigloo Hormoz Nassiri , Raina Jason , Tulandi Togas 
Published: February 2025

Abstract

Objectives:
To evaluate factors associated with malignancy in patients with endometrial polyps.

Materials and Methods:
We conducted electronic database research on PubMed, MEDLINE, EMBASE, COCHRANE, and Google Scholar from inception for all studies on endometrial polyp. After removing duplicates, and title and abstract screening, we had a total of 121 articles and 151 others from screening the reference list. Inclusion criteria included peri and postmenopausal women > 45 years diagnosed histopathologically with endometrial polyp(s). We excluded women with a history of endometrial cancer or hysterectomy.

Results:
Twenty studies were analyzed. Of 11204 patients with endometrial polyp, 287 had malignant polyps (2.75%), 182 (1.8%) had concomitant endometrial hyperplasia with atypia, and 520 (5.2%) had hyperplasia without atypia within the polyp. Menopausal women had a higher risk of pre-malignancy/malignancy than non-menopausal women (OR 5.63 (95CI 3.87, 8.20, I
2 = 0%, P < 0.001). Endometrial thickness on ultrasound in pre-malignancy/malignancy cases was significantly thicker than in the benign polyp (mean difference 4.2 mm, 95% CI 0.8 to 7.6 mm, I
2 = 18%, P = 0.02). Women who used tamoxifen or hormone replacement therapy (HRT) had a lower likelihood of endometrial pre-malignancy/malignancy, while women with abnormal uterine bleeding (AUB) had a higher probability of pre-malignancy/malignancy. The odd ratio of having pre-malignancy/malignancy among those who used tamoxifen was 0.50 (95% CI 0.26-0.94: I
2 12%, p = 0.03).

Conclusion:
In women with endometrial polyp, menopausal age and thickened endometrium might increase the probability while tamoxifen or HRT use might lower the likelihood of endometrial pre-malignancy/malignancy; and the presence of AUB might signal endometrial pre-malignancy/malignancy.
Glazy Erythema on Glans Penis in a 3-year-old Child: An Unusual Diagnosis of Zoon’s Balanitis Aided by Dermoscopy
Authors: Katakam Bhumesh K. , Udhayini Kalimi V. , Chintagunta Sudharani , James Hitha A. 
Published: February 2025

Abstract
Zoon’s balanitis is a benign inflammatory non-venereal genital dermatosis occurring in males. Cayenne pepper spots, a characteristic feature of Zoon’s balanitis, present as erythematous macule with red, pinpoint-like dots. Uncircumcised males between the ages of 40 and 80 are usually affected. Though usually asymptomatic, some individuals may experience discomfort, burning sensations, or pruritus. The majority of the reported cases are older uncircumcised men and the lesion involves glans penis and/or prepuce. We hereby report an uncommon presentation of Zoon’s balanitis in a 3-year-old preschool child.