bluuebunny/crossref_metadata_2025_split huggingface dataset:
Regenerating Mandibular Bone Using rhBMP‐2: Part 2—Treatment of Chronic, Defect Non‐Union Fractures
Authors: Verstraete Frank J.M. , Arzi Boaz , Huey Daniel J. , Cissell Derek D. , Athanasiou Kyriacos A. 
Published: January 2014

ObjectiveTo describe a surgical technique using a regenerative approach and internal fixation for reconstruction of critical size bone defect non‐union mandibular fractures.Study DesignCase series.AnimalsDogs (n = 6) that had internal fixation of defect non‐union mandibular fracture.MethodsIn 5 dogs, the repair was staged and extraction of teeth performed during the initial procedure. After 21–98 days (mean, 27 days) pharyngotomy intubation and temporary maxillomandibular fixation were performed. Using an extraoral approach, a locking titanium miniplate was contoured and secured to the mandible. A compression resistant matrix (CRM) infused with rhBMP‐2 was implanted in the defect. The implant was then covered with a soft tissue envelope followed by surgical wound closure.ResultsAll dogs healed with intact gingival covering over the mandibular fracture site defect and had immediate return to normal function and correct occlusion. Hard‐tissue formation was observed clinically within 2 weeks and solid cortical bone formation within 3 months. CT findings in 1 dog at 3 months postoperatively demonstrated that the newly regenerated mandibular bone had 92% of the bone density and porosity compared to the contralateral side. Long‐term follow‐up revealed excellent outcome.ConclusionMandibular reconstruction using internal fixation and CRM infused with rhBMP‐2 is an excellent solution for the treatment of critical size defect non‐union fractures in dogs.
Perceived motivational team climate in relation to task and social cohesion among male college athletes
Authors: Boyd Michael , Kim Mi‐Sook , Ensari Nurcan , Yin Zenong 
Published: January 2014

AbstractThe purpose of the study was to examine the relationship between perceptions of the motivational team climate and task and social cohesion among male college athletes. Basketball and soccer players (n = 179) completed two response measures, the Perceived Motivational Climate in Sport Questionnaire‐II (Newton, Duda, & Yin) and the Group Environment Questionnaire (GEQ; Carron, Widmeyer, & Brawley) before practice in a team setting near the end of the competitive season. Hierarchical linear modeling analysis revealed that individual perceptions of a task‐involving climate positively predicted, and perceptions of an ego‐involving climate negatively predicted, individual‐attraction‐to‐group task cohesion. Further analysis indicated that perceptions of a task‐involving climate also significantly predicted individual‐attraction‐to‐group social cohesion and group‐integration task cohesion. Perceptions of an ego‐involving climate failed to demonstrate any other predictive value in relation to team cohesion. Discussion underscores the beneficial nature of a task‐involving motivational team climate in regard to the formation and development of task and social cohesion among competitive male college athletes.
In a Spirit of Solidarity? Justifying the European Financial Stability Facility (EFSF) in National Parliamentary Debates
Authors: Closa Carlos , Maatsch Aleksandra 
Published: January 2014

AbstractThis article examines national parliamentarians’ approval of the increased budgetary capacity of theEuropeanFinancialStabilityFacility (EFSF) in autumn 2011. Following the analysis of vote outcome and plenary debates in 11 euro states, it is found that the financial position of a state (creditors versus debtors) does not explain the patterns of support and opposition. Rather, two other factors account for these differences: Euroscepticism, and the government and opposition cleavage. In particular, whereas EuroscepticMPsvoted and argued against theEFSF, the parliamentary majorities supported it. Surprisingly, although the legal basis of theEFSFdraws on solidarity among the European Union Member States, the supporters of theEFSFdid not refer to this principle in their speeches but rather to pragmatic considerations such as national economic interests.
‘Candidatus Phytoplasma asteris’ and ‘Candidatus Phytoplasma aurantifolia’, New Phytoplasma Species Infecting Apple Trees in Iran
Authors: Hashemi‐Tameh Mahdis , Bahar Masoud , Zirak Leila 
Published: January 2014

AbstractDuring several surveys in extensive areas in central Iran, apple trees showing phytoplasma diseases symptoms were observed. PCR tests using phytoplasma universal primer pairs P1A/P7A followed by R16F2n/R16R2 confirmed the association of phytoplasmas with symptomatic apple trees. Nested PCR using 16SrX group‐specific primer pair R16(X)F1/R1 and aster yellows group‐specific primer pairs rp(I)F1A/rp(I)R1A and fTufAy/rTufAy indicated that apple phytoplasmas in these regions did not belong to the apple proliferation group, whereas aster yellows group‐related phytoplasmas caused disease on some trees. Restriction fragment length polymorphism (RFLP) analyses using four restriction enzymes (HhaI, HpaII, HaeIII and RsaI) and sequence analyses of partial 16S rRNA and rp genes demonstrated that apple phytoplasma isolates in the centre of Iran are related to ‘Ca. Phytoplasma asteris’ and ‘Ca. Phytoplasma aurantifolia’. This is the first report of apples infected with ‘Ca. Phytoplasma asteris’ in Iran and the first record from association of ‘Ca. Phytoplasma aurantifolia’ with apples worldwide.
Modification of the Reactive Attitudes
Authors: Goldman David 
Published: January 2014

AbstractIn ‘Freedom and Resentment’ P. F. Strawson argues that reactive attitudes like resentment and indignation cannot be eliminated altogether, because doing so would involve exiting interpersonal relationships altogether. I describe an alternative to resentment: a form of moral sadness about wrongdoing that, I argue, preserves our participation in interpersonal relationships. Substituting this moral sadness for resentment and indignation would amount to a deep and far‐reaching change in the way we relate to each other – while keeping in place the interpersonal relationships, which, Strawson rightfully believes, cannot be eliminated.
Changes in PR and QTc intervals after switching from olanzapine to risperidone in patients with stable schizophrenia
Authors: Suzuki Yutaro , Sugai Takuro , Ono Shin , Sawamura Kazushi , Fukui Naoki , Watanabe Junzo , Tsuneyama Nobuto , Saito Mami , Someya Toshiyuki 
Published: January 2014

AimWe examined the difference between the effects of olanzapine (OLZ) and risperidone (RIS) on PR and QT intervals among patients with stable schizophrenia using a cohort analysis.MethodsTwenty‐one subjects treated with OLZ were enrolled in the study. Following baseline assessments, which included PR and QT intervals, OLZ was switched to RIS for each subject. The same parameters were evaluated following the switch to RIS.ResultsAll patients who had been treated with OLZ were successfully switched to RIS. In all patients, we observed a significant decrease in PR interval (t = 2.397, P = 0.029) and no change in either QTc or RR interval. In female patients, the QTc interval was significantly decreased (t = 3.495, P = 0.008) following the switch, while in male patients, the QTc interval did not change. No patients showed a PR interval of >200 ms or a QTc interval of >500 ms.ConclusionOLZ treatment has a greater prolonging effect on PR and QT intervals compared with RIS. Careful attention may need to be paid to the cardiac conduction system in addition to QT prolongation during OLZ treatment.
Taxonomic revision of three diatoms found in Lake Malawi: Afrocymbella brunii (Fricke) comb. nov., Afrocymbella rossii (Kociolek & Stoermer) comb. nov., and Aulacoseira euareolata (O.Müller) comb. nov. et nom. nov
Authors: Shinohara Kohei , Maruyama Atsushi , Rusuwa Bosco , Ohtsuka Taisuke 
Published: January 2014

SummaryBased on epilithic diatom samples collected from the rocky littoral zone of Lake Malawi (102 diatom taxa belonging to 34 genera were listed in the Supporting Information) we proposed the transfer of three taxa to new genera. Afrocymbella brunii (Fricke) comb. nov. was transferred from Gomphonema because of its dorsiventral valve and its transapically elongated dorsal stigma. Afrocymbella rossii (Kociolek & Stoermer) comb. nov. was also transferred from Gomphocymbella, which is actually a synonym of Gomphonema. Aulacoseira euareolata (O.Müller) comb. nov. et nom. nov. was transferred from Melosira because of the presence of linking spines and mantle areolae, and its specific epithet was replaced because of homonymy with Aulacoseira areolata Moisseeva.
Spatial Prioritization for Biodiversity Restoration: A Simple Framework Referencing Past Species Distributions
Authors: Yoshioka Akira , Akasaka Munemitsu , Kadoya Taku 
Published: January 2014

AbstractThe spatial prioritization of biodiversity restoration sites on a national scale lags behind that of protected areas. We present a simple framework for spatial restoration prioritization using complementarity analysis based on the differences between past and present species distributions and restoration feasibility. In the framework, sites that were not only diverse or unique in the past (high restoration potential), but also have high restoration feasibility (e.g. low anthropogenic pressures) are ranked higher. We applied the framework to endangered bird species that breed in Japan for which distribution data were available from nationwide distribution censuses conducted in 1978 and 1998. The data were compiled in a 20‐km grid resolution across Japan. We incorporated the degree of urbanization and number of farmers as a cost to optimize the sets of cells with regard to restoration feasibility. We successfully identified candidate sets of restoration cells, in which at most six can be allocated for each species under the constraint that the total area selected does not exceed 15% of the degraded cells. At most, 11 cells were allocated for each species under the constraint that restoration cells were within 15% of all ecosystem types. Comparison with the distribution of existing nature restoration sites revealed that only 9.3 or 9.7% (depended on the constraint) of high‐priority cells overlapped cells including existing restoration sites. Our framework provides an objective, efficient method to obtain a testable plan for biodiversity restoration, which might contribute to the attainment of the 2020 target set by the Convention on Biological Diversity.
Allele and haplotype frequencies of HLA‐DPA1 and ‐DPB1 in the population of Guadeloupe
Authors: Voorter C. E. M. , Groeneweg M. , Joannis M.‐O. , Meertens C. , Agis F. , Tilanus M. G. J. 
Published: January 2014

AbstractGenetic polymorphism of human leukocyte antigen (HLA)‐DPA1 and ‐DPB1 loci was studied in 154 unrelated individuals from Guadeloupe, an archipelago of five islands located in the Carribean Sea. Thirty different DPB1 and eight different DPA1 alleles were observed with a heterozygosity index of 0.87 and 0.78, respectively. This high degree of heterozygosity corresponds with those found in African populations. The DPB1* 01:01:01 allele was most frequent (0.260), followed by 02:01:02 (0.143) and 04:01:01 (0.127). The DPA1 alleles 01:03 (0.380), 02:01 (0.302), 02:02 (0.175) and 03:01 (0.123) were identified in >35 individuals each, whereas 01:04, 01:05 and 04:01 were present only once. Haplotype estimations revealed the presence of 39 different haplotypes, with DPB1*01:01:01–DPA1*02:02 and DPB1*02:01:02–DPA1*01:03 as the most frequent (0.143 and 0.140, respectively). A striking difference was observed in DPB1/DPA1 associations between DPB1*04:02 and *105:01, that have identical exon 2 sequences. DPB1*04:02 was exclusively associated with DPA1*01:03, whereas DPB1*105:01 was present with DPA1*03:01, *03:02 or *04:01. This implies that the DP molecules are actually different, and this difference is relevant to consider in studies on the function of HLA‐DP molecules in transplantation. Overall, HLA‐DPA1 and DPB1 allele frequencies and haplotypes of the population of Guadeloupe were most similar to African populations, with characteristic alleles and haplotypes that bespeaks the admixture with other ethnicities.
The Flying Dutchmen: Recent Trends in International Outbound Tourism from the Netherlands
Authors: Zirulia Lorenzo 
Published: January 2014

AbstractThis brief paper focuses on Dutch outbound tourism, that is, international flows with the Netherlands as a place of origin. Using data provided by CBS Statistics Netherlands, we show that the total number of international holidays, both in absolute terms and per capita, has significantly grown in the last three decades, denoting a significant increase in the propensity of Dutch residents to engage in international tourism; moreover, year‐by‐year variations seem to be positively, but weakly, associated with the general conditions of the Dutch economy. In terms of the composition of international holidays by destination country, we found evidence of some instability in the relative importance of different destinations, with an increase in the diversity of choices by Dutch tourists and in the distance of their preferred destination.
Patient characteristics, histopathological findings and outcome in 97 cats with extranodal subcutaneous lymphoma (2007–2011)
Authors: Meichner K. , von Bomhard W. 
Published: January 2014

AbstractThis study describes epidemiologic, clinical, macro‐ and microscopic tumour characteristics and outcome in 97 cats with subcutaneous lymphoma, an uncommon variant of feline extranodal lymphoma. Middle‐aged (median 11 years), male (60.8%), Domestic Shorthair cats (89.7%) were commonly affected. Most tumours presented as a painless, firm, subcutaneous nodule or mass, with predilection to the lateral thoracic or abdominal wall, and the interscapular region. Deep subcutaneous invasion with extension into superficial or underlying tissues, extensive central areas of necrosis and peripheral inflammation were characteristic histopathological findings. Prevalence of retroviral infection was low. Local relapses after therapy were common (43.5%), and 32.2% had distant involvement later in course. Median overall survival was 148 days. Subcutaneous lymphoma should be considered a rare but important differential diagnosis for a subcutaneous mass in cats. Tumours show an aggressive biological behaviour. Treatment options including prognosis should be investigated in further studies.
Genome Sequence of Bacillus cereus Strain LCT-BC235, Carried by the Shenzhou VIII Spacecraft
Authors: Su Longxiang , Wang Tong , Zhou Lisha , Wu Chunyan , Guo Yinghua , Chang De , Liu Yan , Jiang Xuege , Yin Sanjun , Liu Changting 
Published: January 2014

ABSTRACT

In order to explore the effect of space environments on
Bacillus cereus
, we determined the draft genome sequence of a
B. cereus
strain, LCT-BC235, which was isolated after space flight.
Draft Genome Sequence of Petroleum Oil-Degrading Marine Bacterium Pseudomonas taeanensis Strain MS-3, Isolated from a Crude Oil-Contaminated Seashore
Authors: Lee Sang-Yeop , Kim Seon Hee , Lee Dong-Gi , Shin Seyeon , Yun Sung Ho , Choi Chi-Won , Chung Young-Ho , Choi Jong Soon , Kahng Hyung-Yeel , Kim Seung Il 
Published: January 2014

ABSTRACT

Pseudomonas taeanensis
MS-3
T
, isolated from a crude oil-contaminated seashore in South Korea, is capable of degrading petroleum oils, such as gasoline, diesel, and kerosene. Here, we report the draft genome sequence of this strain, which consists of 5,477,045 bp, with a G+C content of 60.72%.
Genome Sequence of Klebsiella pneumoniae Strain LCT-KP182, Which Acquired Hemolytic Properties after Space Flight
Authors: Zhang Xiaojun , Wang Tong , Liu Wenbin , Guo Yinghua , Wang Junfeng , Li Tianzhi , Fang Xiangqun , Zhang Xuelin , Dai Wenkui , Liu Changting 
Published: January 2014

ABSTRACT

The
Klebsiella pneumoniae
strain LCT-KP182 acquired hemolytic properties after space flight. Here, we present the draft genome sequence of this strain.
Genome Sequence of Pseudomonas aeruginosa Strain LCT-PA41, with Changed Metabolism after Space Flight
Authors: Liu Chao , Hu Juan , Fang Xiangqun , Zhang Duchao , Chang De , Wang Junfeng , Li Tianzhi , Guo Yinhua , Dai Wenkui , Liu Changting 
Published: January 2014

ABSTRACT

To explore the effects of space flight on microorganisms,
Pseudomonas aeruginosa
ATCC 27853 was sent into orbit for 398 h on the spacecraft ShenZhou VIII. Here, we present the draft genome sequence of the
P. aeruginosa
strain LCT-PA41, determined after space flight.
Genome Sequence of the Asiatic Species Borrelia persica
Authors: Elbir Haitham , Larsson Pär , Normark Johan , Upreti Mukunda , Korenberg Edward , Larsson Christer , Bergström Sven 
Published: January 2014

ABSTRACT

We report the complete genome sequence of
Borrelia persica
, the causative agent of tick-borne relapsing fever borreliosis on the Asian continent. Its genome of 1,784,979 bp contains 1,850 open reading frames, three ribosomal RNAs, and 32 tRNAs. One clustered regularly interspaced short palindromic repeat (CRISPR) was detected.
Socioeconomic disadvantage and disease-specific mortality in Asia: systematic review with meta-analysis of population-based cohort studies
Authors: Vathesatogkit Prin , Batty G David , Woodward Mark 
Published: January 2014

BackgroundThat socioeconomic deprivation has shown a correlation with disease-specific mortality in Western societies is well documented. However, it is unclear whether these findings are also apparent in Asian societies. Accordingly, we conducted the first systematic review and meta-analysis of studies from Asia that have reported on the association between socioeconomic position and adult mortality risk.MethodsRelevant studies were identified through an electronic search of databases. Studies were included if they had published quantitative estimates of the association between socioeconomic status (SES) and mortality in a general population-based sample. The pooled multiple-adjusted relative risks for mortality in the lowest SES group relative to the highest SES group were studied. Random effects meta-analyses were computed.ResultsA total of 29 cohort studies from 10 Asian countries were identified, comprising 1 370 023 individuals and 71 818 total deaths. The three markers of SES most widely used (education, income, occupation) were inversely related to mortality outcomes under consideration (all-causes, cardiovascular disease, cancer). For instance, the pooled relative risks of low education compared with high education were: 1.40 (95% CI 1.29 to 1.52) for all-cause mortality, 1.66 (1.23 to 2.25) for cardiovascular mortality and 1.16 (1.07 to 1.27) for cancer mortality. There was some evidence that the age of cohort members at study induction, the gross national product of the country from which the cohort was drawn and geographical region modified the association between SES and mortality.ConclusionsConcordant with findings from Western societies, socioeconomic disadvantage is associated with total and cause-specific mortality in Asia.
Effects of Native and Myeloperoxidase-Modified Apolipoprotein A-I on Reverse Cholesterol Transport and Atherosclerosis in Mice
Authors: Hewing Bernd , Parathath Saj , Barrett Tessa , Chung Wing Ki Kellie , Astudillo Yaritzy M. , Hamada Tadateru , Ramkhelawon Bhama , Tallant Thomas C. , Yusufishaq Mohamed Shaif S. , DiDonato Joseph A. , Huang Ying , Buffa Jennifer , Berisha Stela Z. , Smith Jonathan D. , Hazen Stanley L. , Fisher Edward A. 
Published: January 2014

Objective—
Preclinical and clinical studies have shown beneficial effects of infusions of apolipoprotein A-I (ApoA-I) on atherosclerosis. ApoA-I is also a target for myeloperoxidase-mediated oxidation, leading in vitro to a loss of its ability to promote ATP-binding cassette transporter A1-dependent macrophage cholesterol efflux. Therefore, we hypothesized that myeloperoxidase-mediated ApoA-I oxidation would impair its promotion of reverse cholesterol transport in vivo and the beneficial effects on atherosclerotic plaques.

Approach and Results—

ApoA-I
−/−
or apolipoprotein E–deficient mice were subcutaneously injected with native human ApoA-I, oxidized human ApoA-I (myeloperoxidase/hydrogen peroxide/chloride treated), or carrier. Although early postinjection (8 hours) levels of total ApoA-I in plasma were similar for native versus oxidized human ApoA-I, native ApoA-I primarily resided within the high-density lipoprotein fraction, whereas the majority of oxidized human ApoA-I was highly cross-linked and not high-density lipoprotein particle associated, consistent with impaired ATP-binding cassette transporter A1 interaction. In ApoA-I
−/−
mice, ApoA-I oxidation significantly impaired reverse cholesterol transport in vivo. In advanced aortic root atherosclerotic plaques of apolipoprotein E–deficient mice, native ApoA-I injections led to significant decreases in lipid content, macrophage number, and an increase in collagen content; in contrast, oxidized human ApoA-I failed to mediate these changes. The decrease in plaque macrophages with native ApoA-I was accompanied by significant induction of their chemokine receptor CCR7. Furthermore, only native ApoA-I injections led to a significant reduction of inflammatory M1 and increase in anti-inflammatory M2 macrophage markers in the plaques.

Conclusions—
Myeloperoxidase-mediated oxidation renders ApoA-I dysfunctional and unable to (1) promote reverse cholesterol transport, (2) mediate beneficial changes in the composition of atherosclerotic plaques, and (3) pacify the inflammatory status of plaque macrophages.
Physiological Correlates of Beat-to-Beat, Ambulatory, and Day-to-Day Home Blood Pressure Variability After Transient Ischemic Attack or Minor Stroke
Authors: Webb Alastair John Stewart , Rothwell Peter Malcolm 
Published: January 2014

Background and Purpose—
Visit-to-visit and day-to-day variability in systolic blood pressure (SBP) are associated with an increased risk of stroke, more strongly than variability on 24-hour ambulatory BP monitoring, but underlying physiological mechanisms are unclear. We related potentially relevant physiological characteristics to beat-to-beat, ambulatory, and day-to-day BP variability to identify underlying mechanisms and potential therapeutic targets.

Methods—
BP variability (coefficient of variation [CV]) on 1-month home BP monitoring (3 sitting readings, 3× daily), on 24-hour ambulatory BP monitoring, and on 5-minute beat-to-beat monitoring was related to BP reactivity (to mental arithmetic), arterial aging (aortic stiffness: carotid-femoral pulse wave velocity; aortic pulsatility), heart rate variability (CV of normal-to-normal R-R interval), and orthostatic responses.

Results—

In 223 patients within 6 weeks of a transient ischemic attack or minor stroke, beat-to-beat and home SBP-CVs were associated with response to arithmetic (beat-to-beat odds ratio per SD=1.64;
P
<0.0001 and home BP monitoring, 1.41;
P
=0.025), aortic stiffness (1.84;
P
<0.0001 and 1.31;
P
=0.04), aortic pulsatility (1.98;
P
<0.0001 and 1.61;
P
<0.0001), and heart rate variability–CV of normal-to-normal R-R interval (1.34;
P
=0.03 and 1.35;
P
=0.03), independently of age, sex, and aortic BP. Orthostatic BP changes were associated only with SBP-CV on home BP monitoring (0.62;
P
=0.002). In contrast, no physiological measures were associated with within-day BP variability on awake ambulatory BP monitoring except response to mental arithmetic (1.40;
P
=0.01).

Conclusions—
Beat-to-beat and day-to-day SBP variability, but not variability on ambulatory BP monitoring, had similar physiological correlates, suggesting common underlying mechanisms and identifying potentially treatable targets that may be responsible for the relationship between SBP variability and stroke risk.