bluuebunny/crossref_metadata_2025_split huggingface dataset:
Value of true whole-body FDG-PET/CT scanning protocol in oncology: optimization of its use based on primary diagnosis
Authors: Sebro Ronnie , Mari-Aparici Carina , Hernandez-Pampaloni Miguel 
Published: April 2013

Background No standardized field of view (FOV) currently exists for whole-body (WB) positron emission tomography/computed tomography (PET/CT). Limited WB PET/CT FOV can exclude portions of the head, upper, and lower extremities, because there is little perceived clinical benefit to be gained from imaging these areas. Purpose To determine how often utilizing WB PET/CT changes the clinical stage and management compared to each of the limited WB FOVs used for PET/CT. Material and Methods We retrospectively identified 556 oncologic patients (804 PET/CT studies) who underwent staging or restaging PET/CT between November 2010 and November 2011. Abnormal hypermetabolic areas that were suspicious for malignancy in areas that are outside of some of the limited fields of view including in the brain, scalp, and calvarium (above the orbital ridge), in the proximal upper extremity (distal to the humeral neck), distal upper extremity (beyond the elbow), proximal lower extremity (distal to the lesser trochanter), and distal lower extremity (beyond the knees) were recorded. Results A total of 8.5% (47/556) of patients had abnormal findings outside the most limited FOV (skull base to upper thighs) used in PET/CT. More patients had abnormal hypermetabolic lesions in the lower extremity (5.9%) than in the upper extremity (2.3%). Similarly, more patients had abnormal lesions in the proximal (6.5%) compared to the distal (1.4%) upper and lower extremities. The stage was only changed in one patient (0.2%), however new lesions noted in the brain changed management in six patients (1.1%). Melanoma, lymphoma, multiple myeloma, sarcomas and stage IV lung, breast, prostate, bladder, testicular, and renal cancer were more likely to have findings outside the most limited FOV (skull base to upper thighs). Conclusion WB FOV detects additional sites of disease compared to the limited WB FOV, and although these lesions rarely change stage, some of these lesions may change clinical management.
Accuracy of four-dimensional phase-contrast velocity mapping for blood flow visualizations: a phantom study
Authors: Nilsson Anders , Markenroth Bloch Karin , Töger Johannes , Heiberg Einar , Ståhlberg Freddy 
Published: April 2013

Background Time-resolved three-dimensional, three-directional phase-contrast magnetic resonance velocity mapping (4D PC-MRI) is a powerful technique to depict dynamic blood flow patterns in the human body. However, the impact of phase background effects on flow visualizations has not been thoroughly studied previously, and it has not yet been experimentally demonstrated to what degree phase offsets affect flow visualizations and create errors such as inaccurate particle traces. Purpose To quantify background phase offsets and their subsequent impact on particle trace visualizations in a 4D PC-MRI sequence. Additionally, we sought to investigate to what degree visualization errors are reduced by background phase correction. Material and Methods A rotating phantom with a known velocity field was used to quantify background phase of 4D PC-MRI sequences accelerated with SENSE as well as different k-t BLAST speed-up factors. The deviation in end positions between particle traces in the measured velocity fields were compared before and after the application of two different phase correction methods. Results Phantom measurements revealed background velocity offsets up to 7 cm/s (7% of velocity encoding sensitivity) in the central slice, increasing with distance from the center. Background offsets remained constant with increasing k-t BLAST speed-up factors. End deviations of up to 5.3 mm (1.8 voxels) in the direction perpendicular to the rotating disc were found between particle traces and the seeding plane of the traces. Phase correction by subtraction of the data from the stationary phantom reduced the average deviation by up to 56%, while correcting the data-set with a first-order polynomial fit to stationary regions decreased average deviation up to 78%. Conclusion Pathline visualizations can be significantly affected by background phase errors, highlighting the importance of dedicated and robust phase correction methods. Our results show that pathline deviation can be substantial if adequate phase background errors are not minimized.
Volumetric evaluation of dual-energy perfusion CT by the presence of intrapulmonary clots using a 64-slice dual-source CT
Authors: Okada Munemasa , Nakashima Yoshiteru , Kunihiro Yoshie , Nakao Sei , Morikage Noriyasu , Sano Yuichi , Suga Kazuyoshi , Matsunaga Naofumi 
Published: April 2013

Background Dual-energy perfusion CT (DEpCT) directly represents the iodine distribution in lung parenchyma and low perfusion areas caused by intrapulmonary clots (IPCs) are visualized as low attenuation areas. Purpose To evaluate if volumetric evaluation of DEpCT can be used as a predictor of right heart strain by the presence of IPCs. Material and Methods One hundred and ninety-six patients suspected of having acute pulmonary embolism (PE) underwent DEpCT using a 64-slice dual-source CT. DEpCT images were three-dimensionally reconstructed with four threshold ranges: 1–120 HU (V120), 1–15 HU (V15), 1–10 HU (V10), and 1–5 HU (V5). Each relative ratio per V120 was expressed as the %V15, %V10, and %V5. Volumetric data-sets were compared with D-dimer, pulmonary arterial (PA) pressure, right ventricular (RV) diameter, RV/left ventricular (RV/LV) diameter ratio, PA diameter, and PA/aorta (PA/Ao) diameter ratio. The areas under the ROC curves (AUCs) were examined for their relationship to the presence of IPCs. This study was approved by the local ethics committee. Results PA pressure and D-dimer were significantly higher in the patients who had IPCs. In the patients with IPCs, V15, V10, V5, %V15, %V10, and %V5 were also significantly higher than those without IPC ( P ≤ 0.001). %V5 had a better correlation with D-dimer (r = 0.30, P < 0.001) and RV/LV diameter ratio (r = 0.27, P < 0.001), and showed a higher AUC (0.73) than the other CT measurements. Conclusion The volumetric evaluation by DEpCT had a correlation with D-dimer and RV/LV diameter ratio, and the relative ratio of volumetric CT measurements with a lower attenuation threshold might be recommended for the analysis of acute PE.
Sclerosing cholangitis with autoimmune pancreatitis versus primary sclerosing cholangitis: comparison on endoscopic retrograde cholangiography, MR cholangiography, CT, and MRI
Authors: Kim Jin Hee , Byun Jae Ho , Kim So Yeon , Lee Seung Soo , Kim Hyoung Jung , Kim Myung-Hwan , Lee Moon-Gyu 
Published: April 2013

Background It is essential to differentiate sclerosing cholangitis with autoimmune pancreatitis (SC-AIP) from primary sclerosing cholangitis (PSC) as the treatment and prognosis of the two diseases are totally different. Purpose To compare image findings of SC-AIP and PSC on endoscopic retrograde cholangiography (ERC), magnetic resonance cholangiography (MRC), computed tomography (CT), and magnetic resonance imaging (MRI). Material and Methods Two radiologists retrospectively reviewed ERC, MRC, CT, and MRI in 28 SC-AIP and 23 PSC patients in consensus. Factors evaluated included the length, location, and multiplicity of bile duct stricture, the presence of characteristic cholangiographic features of PSC on ERC and MRC, and the presence, location, thickness, and pattern of bile duct wall thickening on CT and MRI. Results On ERC, focal stricture, multifocal and intrahepatic bile duct stricture, and beaded, pruned-tree, and diverticulum-like appearance were more frequent in PSC than in SC-AIP patients ( P ≤ 0.006). On MRC, multifocal and intrahepatic bile duct stricture and pruned-tree appearance were more frequent in PSC than in SC-AIP patients ( P ≤ 0.044). On CT and MRI, the bile duct wall was thicker (5.1 mm vs. 3.1 mm; P = 0.033 and 4.3 mm vs. 3.0 mm; P = 0.01, respectively) in SC-AIP than in PSC patients. PSC was more frequently associated with intrahepatic bile duct wall thickening on both CT (93% vs. 50%; P = 0.024) and MRI (100% vs. 50%; P = 0.023) than SC-AIP. Conclusion The combination of ERC or MRC with cross-sectional images, including CT and MRI, may be helpful in differentiating between SC-AIP and PSC.
Digital tomosynthesis of the thorax: the influence of respiratory motion artifacts on lung nodule detection
Authors: Kim Sung Mok , Chung Myung Jin , Lee Kyung Soo , Kang Hee , Song In-Young , Lee Eun Joo , Hwang Hye Sun 
Published: April 2013

Background Digital tomosynthesis considerably reduces problems created by overlapping anatomy compared with chest X-ray (CXR). However, digital tomosynthesis requires a longer scan time compared with CXR, and thus may be vulnerable to motion artifacts. Purpose To compare the diagnostic performance of digital tomosynthesis in subjects with and without respiratory motion artifacts. Material and Methods The institutional review board approved this retrospective study, and the requirement for written informed consent was waived. A total of 46 subjects with imaging containing respiratory motion artifacts were enrolled in this study, 18 of whom were positive and 28 of whom were negative for lung nodules on computed tomography (CT). The control group was comprised of 92 age-matched subjects with imaging devoid of motion artifacts. Of these, 36 were positive and 56 were negative for lung nodules on subsequent CT scan. The size criteria of nodules were 4–10 mm. Three chest radiologists independently evaluated the radiographs and digital tomosynthesis images for the presence of pulmonary nodules. Multireader multicase receiver-operating characteristic (ROC) analyses was used for statistical comparisons. Results Within the control group, the areas under curve (AUC) for observer performances in detecting lung nodules on digital tomosynthesis was higher than that on CXR ( P = 0.017). Within the study group, there were no significant differences in AUCs for observer performances ( P = 0.576). Conclusion When no motion artifacts are present, the detection performance of nodules (4–10 mm) on digital tomosynthesis is significantly better than that on CXR, whereas there is not a significant difference in cases with motion artifacts.
Right bronchopleural fistula treated with a novel, Y-shaped, single-plugged, covered, metallic airway stent
Authors: Wu Gang , Li Zong-Ming , Han Xin-Wei , Wang Zhong-Gao , Lu Hui-Bin , Zhu Ming , Ren Ke-Wei 
Published: April 2013

Background Bronchopleural fistula (BPF) is an infrequent but life-threatening complication after pneumonectomy. The incidence of BPF reported in the literature varies from 0.3% to 20%. Purpose To determine the feasibility and efficacy of using Y-shaped, single-plugged, covered, metallic stents to treat right bronchopleural fistulas. Material and Methods We have designed a Y-shaped, single-plugged, covered, self-expandable, metallic airway stent to fit the specific anatomy of the right main bronchus. The stent has a main tube and two branches, resembling an inverted “Y”. One of the branches is closed (plugged) and bullet-shaped; the other one tubular and open. The entire stent is encased in a nitinol wire mesh. Stent size can be individualized using multislice spiral computed tomography (MSCT) measurements of the airways. Under fluoroscopic guidance, we have implanted 15 Y-shaped stents in 15 patients with right bronchopleural fistulas. Results Stent insertion was successful in all patients. All fistulas were successfully closed immediately after stent placement. Follow-up was performed for 1–34 months. Positive clinical outcomes were seen in 13 of 15 patients. Two patients died of intractable pulmonary infection and multiorgan failure. The fistula completely healed and the stent could be removed in five patients; however, two of them were left with a small, aseptic, residual right lung cavity. The remaining eight patients are still alive with the stent in situ. Conclusion The placement of Y-shaped, single-plugged, covered, self-expandable metallic airway stents seems to be a feasible and safe method for the treatment of bronchopleural fistulas involving the right main bronchus. This stent is a promising therapeutic alternative for bronchopleural fistulas involving the right main bronchus.
MRI white matter lesions in pediatric migraine
Authors: Eidlitz-Markus Tal , Zeharia Avraham , Haimi-Cohen Yishay , Konen Osnat 
Published: April 2013

Objectives: Studies have reported an association between migraine and white matter hyperintensities on T2-weighted brain magnetic resonance imaging (MRI) in adults. The aim of the present study was to evaluate white matter MRI brain findings in pediatric patients with migraine. Methods: The medical files and imaging scans of all 194 patients who underwent brain MRI at the headache clinic of a tertiary medical center in 2008–2011 were reviewed. Results: Mean age was 10.9 ± 3.5 years. Migraine was diagnosed in 131 patients and other disorders in 63. In the migraine group, findings on physical and laboratory examinations were within normal range. White matter lesions were identified on MRI scan in 14 children with migraine (10.6%) and none of the children with other disorders ( p = 0.006). In 13/14 patients, the lesions were focal with a variable distribution; in the remaining patient, confluent periventricular hyperintensities were documented. Conclusions: In a headache clinic of a tertiary pediatric medical center, white matter lesions are found in about 10% of pediatric patients with migraine.
Unilateral nasal pain with migraine features
Authors: Álvarez Mónica , Montojo Teresa , de la Casa Beatriz , Vela Lydia , Pareja Juan A 
Published: April 2013

Background: Migraine attacks exclusively felt in the face are very rare, the pain involving the territories supplied by the second and third branches of the trigeminal nerve. Cases: Two patients suffering from heminasal pain attacks accompanied with typical migrainous features and responsive to oral or intranasal triptans – but not to intranasal lidocaine or oxymetazoline. In one patient, the attacks could be precipitated upon slight touching on the tip of the nose, in the other attacks were preceded by the nasal sensation typically heralding sneezing. Discussion: Migraine pain mostly develops within the innervation territory of the first branch of the trigeminal nerve, which includes the nose. Therefore, episodes of unilateral nasal pain with migrainous features could be considered a migraine with unusual topography (nasal migraine). Painful nasal attacks occasionally preceded by stimulation of trigeminal afferents in the nose, could be conceived of as migraine-tic syndrome.
Operative Management of Partial-Thickness Tears of the Proximal Hamstring Muscles in Athletes
Authors: Bowman Karl F. , Cohen Steven B. , Bradley James P. 
Published: April 2013

Background: Partial tears of the hamstring muscle origin represent a challenging clinical problem to the patient and orthopaedic surgeon. Although nonoperative treatment is frequently met with limited success, there is a paucity of data on the efficacy of surgical management for partial proximal hamstring tears in the active and athletic population. Purpose: To evaluate the results of an anatomic repair for partial tears of the hamstring muscle origin in athletes. Study Design: Case series; Level of evidence, 4. Methods: The records of 17 patients with partial tears of the proximal hamstring origin were reviewed after institutional review board approval was obtained. All patients were treated with open debridement and primary tendon repair after failure of at least 6 months of nonoperative therapy. Clinical and operative records, radiographs, and magnetic resonance images were reviewed for all patients. A patient-reported outcomes survey was completed by 14 patients that included the Lower Extremity Functional Score (LEFS), Marx activity rating scale, custom LEFS and Marx scales, and subjective patient satisfaction scores. Early and late postoperative complications were recorded. Results: There were 3 male and 14 female patients; their average age was 43 years (range, 19-64 years) and average follow-up was 32 months (range, 12-51 months). There were 2 collegiate athletes (field hockey, track), 14 amateur athletes (distance running, waterskiing, tennis), and a professional bodybuilder. Postoperative LEFS was 73.3 ± 9.9 (range, 50-80) and custom LEFS was 66.7 ± 17.0 (range, 37-80) of a maximum 80 points. The most commonly reported difficulty was with prolonged sitting and explosive direction change while running. The average Marx score was 6.5 ± 5.3 (range, 0-16) of a maximum 16, correlating with a greater return to recreational running activities in this patient cohort than regular participation in pivoting or cutting sports. Marx custom scores were 20 of a maximum 20 in all patients, demonstrating no disability in the operative extremity with activities of daily living. No patient underwent a subsequent surgery. One patient was not satisfied with the result and reported persistent symptoms during competitive distance running. All patients were able to return to their preoperative level of activity after surgery. Conclusion: Anatomic surgical treatment of partial proximal hamstring avulsions can lead to satisfactory functional outcomes, a high rate of return to athletic activity, and low complication rate. This procedure should be reserved for patients who have failed an extended course of nonoperative treatment, and the proximity of the sciatic nerve mandates a careful assessment of the risk-benefit ratio before surgery is undertaken.
Le lien entre le consommateur et ses actes
Authors: Julienne Eric 
Published: April 2013

Résumé Alors que la littérature marketing explique habituellement l’engagement par des construits attitudinaux tels que la confiance et l’attachement, nous développons une approche comportementale alternative selon laquelle l’engagement résulte de l’accumulation d’actes d’achat et de consommation (Kiesler, 1971). Nous montrons que (1) le pouvoir prédictif d’un modèle comportemental, testé sur un échantillon de 432 lecteurs de presse magazine, est équivalent à celui d’un modèle attitudinal classique (variance expliquée: 0.529 vs. 0.527), et (2) l’accumulation des actes ne renforce pas l’influence des attitudes sur l’engagement (variance expliquée du modèle intégrateur attitudes–comportements: 0.546). Ces résultats suggèrent d’utiliser préférentiellement les données comportementales pour prédire l’engagement, car elles sont plus faciles à collecter.
Les rôles des ‘co-clients’ et leurs mécanismes d’influence sur la satisfaction globale durant une expérience de service
Authors: Camelis Christèle , Dano Florence , Goudarzi Kiane , Hamon Viviane , Llosa Sylvie 
Published: April 2013

Résumé L’objectif de cet article est de montrer comment les interactions avec les clients initialement inconnus mais présents lors de l’expérience de service, que nous appelons ‘co-clients’, influencent la satisfaction immédiate du consommateur envers le service délivré. Cette recherche exploratoire s’appuie sur une étude qualitative croisant plusieurs méthodes, menée sur deux services: un voyage en train et un cours de fitness. Elle identifie six rôles joués par les co-clients sur la satisfaction et quatre mécanismes d’influence sous-jacents. Les autres clients informent sur le service à venir, posent les règles sociales, sont un standard de comparaison, distraient, perturbent et aident à participer. L’influence de ces rôles sur la satisfaction se manifeste par la modification des attentes et de la performance perçue, directement ou via la participation, et à travers le sentiment d’équité. Elle est par ailleurs modérée par des variables situationnelles.
L’avatar en marketing: synthèse, cadre intégrateur et perspectives
Authors: Garnier Marion , Poncin Ingrid 
Published: April 2013

Résumé Face à une littérature marketing encore récente sur le sujet de la représentation graphique du consommateur en ligne et ses effets sur la consommation et les échanges, cet article réalise une synthèse multidisciplinaire sur ce thème. Un modèle intégrateur focalisé sur le processus d’identification à l’avatar, ses antécédents et ses conséquences dans un contexte commercial est proposé. Enfin, des propositions de recherche concrètes sont formulées.
Treatment of Osteochondral Lesions of the Talus With Particulated Juvenile Cartilage
Authors: Coetzee J. Chris , Giza Eric , Schon Lew C. , Berlet Gregory C. , Neufeld Steven , Stone Rebecca M. , Wilson Erin L. 
Published: April 2013

Background: Numerous modalities are used today to treat symptomatic osteochondral lesions in the ankle. However, there are ongoing challenges with the treatment of certain lesions, and concerns exist regarding long-term effectiveness. Methods: The purpose of the study was to collect clinical outcomes of pain and function in retrospectively and prospectively enrolled patients treated with particulated juvenile cartilage for symptomatic osteochondral lesions in the ankle. This study collected outcomes and incidence of reoperations in standard clinic patients. The analysis presented here includes final follow-up to date for 12 males and 11 females representing 24 ankles. Subjects had an average age at surgery of 35.0 years and an average body mass index of 28 ± 5.8. Fourteen ankles had failed at least 1 prior bone marrow stimulation procedure. The average lesion size was 125 ± 75 mm2, and the average depth was 7 ± 5 mm. In conjunction with the treatment, 9 (38%) ankles had 1 concomitant procedure and 9 (38%) had more than 1 concomitant procedure. Clinical evaluations were performed with an average follow-up of 16.2 months. Results: Average outcome scores at final follow-up were American Orthopaedic Foot & Ankle Society Ankle-Hindfoot Scale 85 ± 18 with 18 (78%) ankles demonstrating good to excellent scores, Short-Form 12 Health Survey (SF12) physical composite score 46 ± 10, SF12 mental health composite score 55 ± 7.1, Foot and Ankle Ability Measure (FAAM) activities of daily living 82 ± 14, FAAM Sports 63 ± 27, and 100-mm visual analog scale for pain 24 ± 25. Outcomes data divided by lesion size demonstrated 92% (12/13) good to excellent results in lesions 10 mm or larger and those smaller than 15 mm. To date, 1 partial graft delamination has been reported at 16 months. Conclusions: Preliminary data from a challenging clinical population with large, symptomatic osteochondral lesions in the ankle suggest that treatment with particulated juvenile cartilage could improve function and decrease pain. Longer follow-up and additional subjects are needed to evaluate improvement level and ideal patient indications. Level of Evidence: Level IV, case series.