bluuebunny/crossref_metadata_2025_split huggingface dataset:
Stumpfstöße von Stahlbetonstützen mit hochfestem Betonstahl und großen Bewehrungsgraden
Authors: Glaßner Johannes , Vojvodic Goran , Tue Nguyen Viet 
Published: August 2024

AbstractIm Hochhausbau stellen Stahlbetonstützen mit hohem Bewehrungsgrad und hochfesten Betonstählen aufgrund von wesentlichen Vorteilen in Herstellung und Kosten eine gute Alternative zu Stahl‐ und Verbundstützen dar. Ein bedeutendes Konstruktionselement dieses Stützentyps ist der Stumpfstoß aus Stahlplatte und Mörtelfuge, da gewöhnliche Übergreifungen der Bewehrungsstäbe oder Muffenstöße wegen hoher einhergehender Spaltzugkräfte nicht geeignet sind. Zur Untersuchung des Einflusses des Stumpfstoßes auf die Traglast der hochfesten Stahlbetonstützen wurde eine Versuchsserie mit 16 Prüfkörpern durchgeführt. Es zeigt sich, dass durch den Kontaktstoß der Bemessungswert der Streckgrenze des hochfesten Betonstahls überwunden werden kann, sofern der verwendete Beton eine ausreichende Verformungsfähigkeit aufweist. Bei einer Ausführung mit hoher Genauigkeit des Bewehrungskorbs sind kaum Lastumlagerungen zwischen Längsbewehrung und Beton im unmittelbaren Bereich des Stumpfstoßes zu erwarten. Insgesamt konnten entgegen vorangegangener Forschungsergebnisse keine negativen Auswirkungen aufgrund von Stumpfstößen festgestellt werden. Die bei hohen Bewehrungsgraden beobachteten frühzeitig auftretenden lokalen Abplatzungen der Betondeckung konnten auf die Verformung der angrenzenden Stahlplatten gegenüber der Prüfmaschine zurückgeführt werden.
Coconut husk waste products valorization for fabrication of luminescent titanium dioxide NPs as powerful tool for photodecomposition and food born infection: A sustainable strategy
Authors: Thiyakarajan Sutharappa Kaliyamoorthy , Vijayakumar Subramaniyan , Sriban Kannan , Vidhya Elavarasan , Prathipkumar Subramaniyan , Wadaan Mohammad Ahmad , Mythili Raja 
Published: August 2024

AbstractFabricating metal oxide nanoparticles has garnered much attention lately because creating safe chemicals, sustainable materials, economic processes, and renewable resources is becoming increasingly important. This research shows how TiO2 nanoparticles (NPs) could be generated in an ecologically responsible way using waste coconut husk with the help of tender coconut. This extract functions as both a reducing agent and a sealing agent. The investigation of TiO2 NPs exploited ultraviolet (UV), X‐ray diffraction (XRD), Fourier transform infrared spectroscopy (FT‐IR), and field‐emission scanning electron microscopy (FE‐SEM) with energy‐dispersive X‐ray (EDX) methods. The germicidal properties of TiO2 NPs against food‐borne pathogenic strains were studied using the agar well method. Employing Congo red pigment, the photodecomposition behavior was investigated. The TiO2 NPs produced had a crystallite size measuring 16.2 nm. The average grain size of the sample, as measured by FE‐SEM inspection, falls within the range of 15 to 25 nm. Impressive anti‐germ effects against food‐borne germs like Gram‐positive (Staphylococcus aureus and Listeria monocytogenes), Gram‐negative (Salmonella typhimurium and Escherichia coli) bacteria, and fungi (Candida albicans and Aspergillus niger) have been proved by the sustainable fabrication of TiO2 NPs. The catalytic effectiveness of Congo red decreased by 88% after 90 min. The findings suggest that sustainable synthesis of TiO2 NPs is an effective tool for food‐borne germicides and photodecomposition behaviors.
Donor–acceptor–donor type AIEgens based on thieno[3.4‐c]pyrrole‐4,6‐dione: Synthesis, electropolymerization, and electrochromism
Authors: Xu Zhe , Ming Shouyi , Zhang Teng , Li Meijing , Zhen Shijie 
Published: August 2024

AbstractPhotoelectric functional materials with electrochemical reversible activity and fluorescence intensities have attracted significant interest due to their wide range of applications in optoelectronic devices. In this work, a series of photoresponsive and electroactive monomers based on thieno[3.4‐c]pyrrole‐4,6‐dione (TPD) are synthesized and characterized. They possess planar geometry with smaller dihedral angles owing to the existence of a noncovalent conformation lock coming from the S atoms and the O atoms. Crystallographic, spectroscopic, and computational results reveal that the introduction of the TPD unit can endow the monomers with aggregation‐induced emission (AIE), reduced energy levels, and increased electrochemical activity. The monomers were successfully polymerized through the electrochemical method, and the corresponding polymers displayed reversible electrochemical activity and stability. Moreover, polymer films based on 3,3‐dimethyl‐3,4‐dihydro‐2H‐thieno[3,4‐b][1,4]dioxepine (ProE)‐TPD have electrochromic properties in the near‐infrared field with a high value of optical contrast ratio (∆T) of 27.1% at 1000 nm.
Innovative indenone‐derivative colorimetric fluorescent probe: A approach for copper ion detection in water
Authors: Hui Peichen , Shi Yanfeng , Xu Zhenghe , Xu Jing , Zhu Baocun , Xu Lirong , Liu Bowen , Zhang Erchi 
Published: August 2024

AbstractCopper (Cu2+) is a metal chemical element closely related to human life and is widely used in many fields. However, with the discharge of copper wastewater, the water quality will be seriously affected, leading to excessive intake of Cu2+ and a variety of diseases. Hence, there is a pressing need for an effective detection method for Cu2+ in aqueous environments. Leveraging the remarkable attributes of GFP chromophores and indenone derivatives, we have created a novel colorimetric fluorescent probe P‐Cu2+, tailored for efficient copper ion detection. The addition of Cu2+ causes the solution to visibly change from colorless to a pronounced yellow, enabling naked‐eye detection and offering promise for real sample analysis.
Optimization of Alkali Treatment Conditions of Ramie Fabrics Using Box–Behnken Method
Authors: Wagaye Bewuket Teshome , Guo Jiansheng 
Published: August 2024

ABSTRACTRamie is a widely used plant fiber for making textiles and reinforcement in biodegradable composites. Pretreating cellulosic fibers with alkali before producing composites is increasingly used to enhance adhesion with polymeric resin. In this work, response surface methodology (RSM) based on the Box–Behnken technique was utilized to investigate the impact of independent variables on ramie fabric characteristics and determine the optimal treatment condition. The impact of alkali concentration, treatment time, and temperature on the breaking load and elongation at break of woven ramie fabrics were evaluated using Design‐Expert software, which established the design matrix and analyzed the experimental data employing numerical and graphical optimization methods. Moreover, the impact of alkali treatment conditions on the surface morphology, structural change of ramie fabrics, and thermal properties was investigated. Based on the analysis of variance (ANOVA) results, the suggested quadratic models can adequately predict the breaking load and elongation at break of the ramie woven fabrics within the range of conditions applied in this investigation. The RSM revealed that an alkali concentration of 6.12%, a treatment time of 30 min, and a temperature of 39.13°C resulted in an optimum treatment condition with a breaking load of 518.28 N and elongation at break of 23.36%.
The effect of beliefs and self‐efficacy on the levels of sexual abuse‐related anxiety in parents of children with disabilities
Authors: Özkan Filiz , Uzdil Nurcan , Karakaya Serkan , Köseoğlu Bülent 
Published: August 2024

AbstractThis study was conducted to investigate the relationship between self‐efficacy, sexual abuse‐related anxiety and belief levels of the parents of children receiving special education support. The study was descriptively conducted with the parents of 141 students who received special education in primary school in Kayseri in the 2021–2022 academic year. Parent information form, Parental Beliefs Form on Child Sexual Abuse (PBFCSA), Sexual Abuse Parental Anxiety Scale (SAPAS) and Parental Self‐Efficacy Instrument for Children with Disabilities (PSICD) were used in the study. Independent samples t test, Pearson rank correlation coefficient and multiple linear regression analysis were used for data analysis. In the study, statistically significant and positive correlations were found between parental beliefs about sexual abuse and anxiety about sexual abuse (r = 0.318; 95% CI [0.188, 0.438]), between anxiety about sexual abuse and parental self‐efficacy (r = 0.389; 95% CI [0.213, 0.531]) and between parental beliefs about sexual abuse and parental self‐efficacy (r = 0.324; 95% CI [0.116, 0.514]). In the study, it was found that 24.4% of parental anxiety was explained by parental self‐efficacy, beliefs about sexual abuse, parent status, working status and age. In the study, a weak but positive and significant relationship was found between parental beliefs about sexual abuse and anxiety about sexual abuse. It is recommended that studies should be conducted to determine appropriate coping methods for parents' concerns about sexual abuse and to monitor changes in their beliefs and self‐efficacy. In addition, it is predicted that applied studies addressing self‐efficacy and beliefs should be conducted to understand how levels of anxiety might be reduced.
Rental subsidies and take‐up barriers in an era of expensive rents: An extended version of the theory of planned behaviour
Authors: Flynn Lindsay , Buscicchio Giulia 
Published: August 2024

AbstractDespite increasing rent price burdens throughout Europe, many eligible households for rental subsidies do not use them. Understanding determinants of low take‐up is crucial for evaluating program effectiveness and anticipating fiscal implications. To identify those determinants, we built an extended version of the theory of planned behaviour, incorporating dimensions from the claiming costs scale. In an online survey, participants comprising renting households likely eligible for the housing subsidy from Germany (n = 862) and Spain (n = 1032) completed measures of behavioural intention, rental cost burdens, theory of planned behaviour constructs (attitudes, subjective norms, perceived behavioural control, and past behaviour), and claiming costs constructs (information costs, process costs, and stigma). Results supported a multi‐group model, showing different paths for Germany and Spain. Several similar paths were identified for both countries, such as the indirect association of stigma with intention to apply for rental subsidies via attitude, the positive and strong association of subjective norms, and the positive association between perceived behavioural control and intention. The indirect relationship involving information costs was observed for Spain but not Germany, and rental cost burdens operated differently as well. These findings suggest that multiple dimensions, both psychological and policy‐related, should be considered when investigating claiming behaviours for rental subsidies, while emphasizing the need to acknowledge the unique characteristics of each country. This evidence is also relevant to policymakers, offering insights into leveraging established policy tools. Please refer to the Supplementary Material Section to find this article's Community and Social Impact Statement.
METTL3 mediated ferroptosis in chondrocytes and promoted pain in KOA via HMGB1 m6A modification
Authors: Bao Tianchi , Liao Taiyang , Cai Xuefeng , Lu Binjie , Dai Gaole , Pei Shuai , Zhang Yunqing , Li Yuwei , Xu Bo 
Published: August 2024

AbstractMethyltransferase‐like 3 (METTL3) plays a role in the development of knee osteoarthritis (KOA). However, the mechanism underlying the role of METTL3 in KOA is unclear. This work investigated the effects of MELLT3 on ferroptosis and pain relief in in vitro and in vivo KOA models. Chondrocytes were treated with 10 ng/mL interleukin‐1β (IL‐1β) or 5 μM Erastin (ferroptosis inducer). IL‐1β or Erastin treatment inhibited cell viability and glutathione levels; increased Fe2+, lipid reactive oxygen species and malondialdehyde production; and decreased glutathione peroxidase 4, ferritin light chain and solute carrier family 7 member 11 levels. The overexpression of METTL3 facilitated the N6‐methyladenosine methylation of high mobility group box 1 (HMGB1). HMGB1 overexpression reversed the effect of sh‐METTL3 on IL‐1β‐treated chondrocytes. A KOA rat model was established by the injection of monosodium iodoacetate into the joints and successful model establishment was confirmed by haematoxylin and eosin staining and Safranin O/Fast Green staining. METTL3 depletion alleviated cartilage damage, the inflammatory response, ferroptosis and knee pain in KOA model rats, and these effects were reversed by the addition of HMGB1. In conclusion, METTL3 depletion inhibited ferroptosis and the inflammatory response, and ameliorated cartilage damage and knee pain during KOA progression by regulating HMGB1.
Pelvic inflammatory disease associated with cytomegalovirus infection in an immunocompetent adult: Case report and literature review
Authors: Nitta Yuto , Shibata Takashi , Kato Hiroki , Nakago Satoshi 
Published: August 2024

Key Clinical MessagePelvic inflammatory disease associated with cytomegalovirus infection in immunocompetent adults might be difficult to diagnose because of the rarity and relatively inconspicuous symptoms of infectious mononucleosis. Even if the main complaint is lower abdominal pain, careful search for symptoms latent outside the abdomen could lead to the diagnosis.
Effectiveness of rehabilitation for young patients with extensive right hemisphere cerebral infarction: A report of two cases
Authors: Nakamura Tomoyuki , Kurosaki Shuhei , Baba Mikoto , Irisawa Hiroshi , Mizushima Takashi 
Published: August 2024

Key Clinical MessageIn younger patients, including those with extensive infarction involving the anterior and middle cerebral artery regions of the right hemisphere, appropriate treatment for rare causes and goal‐oriented long‐term rehabilitation could improve severe hemiplegia and higher brain dysfunction, and allow for further education and employment.AbstractAlthough the number of young stroke patients is small, many have serious sequelae and rare causes. In addition to independence in activities of daily living, education and employment are desired. We present two cases of extensive infarction in the right cerebrum in patients who underwent rehabilitation with good outcomes.
Decomposition of N2O by Ruthenium Catalysts – RuO2 as Active Phase on Non‐Reducible Supports
Authors: Zhang Xiaoqiao , Zheng Jian , Boch Florian Johannes , Nickl Simon , Köhler Klaus 
Published: August 2024

AbstractRuthenium has been supported on specifically chosen non‐reducible supports (Al2O3, SiO2, Al2O3‐SiO2 mixed oxides, Mg/ZnAl2O4 spinel, and AlF3), and these catalysts have been tested in the decomposition of nitrous oxide, N2O, to identify the catalytically active phase of ruthenium. Pure, bulk ruthenium dioxide, RuO2, and isolated Ru surface complexes have been synthesized and investigated for comparison. The catalysts were characterized by X‐ray diffraction, H2 chemisorption, N2 physisorption, temperature‐programmed reduction, and desorption (TPR/TPD) and in situ infrared spectroscopy (IR). All aimed experiments strongly indicate that the decomposition of N2O occurs on ruthenium dioxide, RuO2, instead of metal particles. H2 pre‐reduction to Ru metal has inhibitory effects for all oxygen‐containing supports. The activity increases with the dispersion of ruthenium oxide. Bulk RuO2 showed the best catalytic performance.
Smart Materials for Biocatalysis Regulation through Thermoresponsive Polymers
Authors: de Barros Heloise R. , Theisen Maíra , Durigon Maria Clara , Leite Daiani C. , Piovan Leandro , Riegel‐Vidotti Izabel C. 
Published: August 2024

AbstractTemperature‐responsive biocatalytic hybrid materials offer several advantages, such as improved stability, enhanced catalytic efficiency, and biocatalysts longer lifespan. Combining enzymes with thermoresponsive polymers in a strategically manner allows a smarter modulation of enzyme activity in response to temperature changes. Thermoresponsive materials can act as protective barriers for enzymes or enable controlled exposure and release depending on temperature variations, expanding enzyme applications in diverse environments. This review aims to comprehensively present the design strategies for enzyme‐polymer hybrid materials with thermoresponsive properties, and to address the advantages, applications, and challenges involved for a rational control of biocatalytic systems. The study emphasizes the importance of creating stimuli‐responsive biocatalytic hybrid materials for diverse applications, ranging from controlled drug delivery to industrial catalysis. Furthermore, we outline key research opportunities and future perspectives for studies within this scope.
Systematic reviews of clinical laboratory studies: Pilot risk of bias tool developed by consensus
Authors: Fox Tilly , Hunt Beverley J. , Ariens Robert A. S. , Towers Greg J. , Lever Robert , Garner Paul , Kuehn Rebecca 
Published: August 2024

AbstractIntroductionSome research studies aim to elucidate pathophysiology by examining blood or tissue markers in relation to clinical findings. In COVID‐19, this has led specialists to promote treatment options based on single studies without systematic appraisal and critical summaries of the data. As we could not identify any published tools for this purpose, we developed a pilot risk of bias tool by consensus, and report here on our approach.MethodsUsing an expert consultative consensus process, a panel of five topic experts were guided through a set of iterative steps to develop questions intended to elicit information about the study methods and reporting in clinical laboratory studies. The team piloted the tool in three clinical laboratory studies, and then applied it formally as a component in assessing a hypothesis about mechanisms in the post‐COVID‐19 condition as part of a Cochrane review.ResultsThe pilot tool assessed study quality and bias across three domains applicable to comparative and single‐arm clinical laboratory studies: collection and handling of samples, experimental methods, and reporting of the results. In the Cochrane review, the tool identified substantive risk of bias in the included clinical laboratory studies.ConclusionThe plethora of COVID‐19 research has highlighted the need for formal methods to systematically appraise clinical laboratory studies related to disease pathology. This tool provides a systematic approach to appraise the validity of these studies. Our process may guide others in the development of appraisal tools in areas where they are needed. Given the relationship between clinical laboratory studies and the development of medical treatments, further development of this risk of bias tool is important for evidence‐based healthcare and research.
A Unified Approach for the Prediction of Dry Pressure Drop in Knitted‐Wire Mesh Demisters
Authors: Döß Alexander , Schubert Markus , Bieberle André , Johnson Jesline , Kryk Holger , Flegiel Felix , Hampel Uwe 
Published: August 2024

AbstractThe removal of unwanted droplets in thermal separation units is often accomplished using knitted wire meshes. Alongside the separation efficiency, the pressure drop plays a crucial role for the design of these demisters. Wire meshes have been subject to limited investigations, and correlations for predicting the pressure drop, both with or without loading (referred to as dry pressure drop), have not yet been validated. To address this gap, experimental analyses of porosity and dry pressure drop were conducted over a wide range of wire mesh parameters and intake gas velocities. An empirical correlation was developed from these experimental results and further data from the literature. This correlation enables prediction of the pressure drop with a mean deviation of ±20 %.
Effect of Itraconazole, a CYP3A4 Inhibitor, and Rifampin, a CYP3A4 Inducer, on the Pharmacokinetics of Vatiquinone
Authors: Lee Lucy , Thoolen Martin , Ma Jiyuan , Kaushik Diksha , Golden Lee , Kong Ronald 
Published: August 2024

AbstractVatiquinone is a small molecule inhibitor of 15‐lipoxygenase in development for patients with Friedreich's ataxia. The objective of this analysis was to determine the effect of a cytochrome P450 isoform 3A4 (CYP3A4) inhibitor and inducer on vatiquinone pharmacokinetics (PKs). The coadministration of 400 mg of vatiquinone with 200 mg of itraconazole (a CYP3A4 inhibitor) resulted in increased maximum observed concentration (Cmax) of vatiquinone and systemic exposure (AUC0‐inf) by approximately 3.5‐ and 2.9‐fold, respectively. The coadministration of 400 mg of vatiquinone with 600 mg of rifampin (a CYP3A4 inducer) resulted in decreased vatiquinone Cmax and AUC0‐inf by approximately 0.64‐ and 0.54‐fold, respectively. The terminal half‐life of vatiquinone was not affected by itraconazole or rifampin. These clinical study results confirm the in vitro reaction phenotyping data that shows that CYP3A4 plays an important role in vatiquinone metabolism. The result of this analysis together with phase 3 efficacy and safety data, population PK analysis, and the exposure‐response relationship will determine if the extent of vatiquinone changes in the presence of CYP3A4 inhibitors and inducers are considered clinically relevant.
Regulating the Pore Structure and Heteroatom Doping of Soybean Straw Carbon Based on a Bifunctional Template Method for the High‐Performance Carbon Supercapacitor
Authors: Guo Lingyu , Jiao Shenghui , Wei Guijuan , Zhao Xixia , Zhang Junliu , Zhang Huixin , Zhao Xin , Chen Honglei , Ji XingXiang 
Published: August 2024

AbstractThe previous research addressed the waste problem of agriculture and forestry residues by exploring the efficient utilization of liquefied soybean straw in supercapacitor. The structures of the liquefied soybean straw were controlled by coupling microwave hydrothermal treatment with carbonization under the influence of a C3N4 bifunctional template. What′s more, C3N4 could effectively regulate the pore structures and provide an effective N active site of carbon materials C3N4. The obtained N‐SLR Carbon‐700 possess a specific surface area of up to 1593.7 m2 g −1, and the pore size is mainly concentrated in the range of 1.8–2.5 nm, providing efficient ions transmission channels and storage space. Its specific capacitance is up to 261.5 F g−1 (current density of 0.5 A g−1), and the capacity retention is 74.04 % when the current density is expanded by 20 times. In the two‐electrode system, the energy density of N‐SLR Carbon‐700 could reach to 31.3 W h kg−1 at a power density of 360 W kg−1, as well as the energy surface density is maintained at 69 % when the power density is increased by a factor of 20. This work enhances effectively the charging and discharging stability and capacitance value of carbon‐based supercapacitor.
Upcycling of Chitin to Cross‐Coupling Catalysts: Tailored Supports and Opportunities in Mechanochemistry
Authors: Trentin Oscar , Ballesteros‐Plata Daniel , Rodríguez‐Castellón Enrique , Puppulin Leonardo , Selva Maurizio , Perosa Alvise , Rodríguez‐Padrón Daily 
Published: August 2024

AbstractIn this study chitin derived from shrimp shells was used in the design of heterogeneous Pd‐based catalysts for Heck and Suzuki‐Miyaura cross‐coupling reactions. The synthesis of Pd nanoparticles supported on N‐doped carbons was performed through different approaches, including a sustainable mechanochemical approach, by using a twin‐screw extruder. All catalytic systems were characterized by a multitechnique approach and the effect of nanoparticles size, N‐doping on the support, and their synergistic interactions were elucidated. Specifically, Kelvin Probe Atomic Force Microscopy provided valuable insights on charge transfer and metal‐support interactions. The catalytic behaviour of the samples was investigated in cross‐coupling reactions under batch conditions and under semi‐continuous flow solvent‐free conditions, respectively obtaining a quantitative yield and a noteworthy productivity of 8.7 mol/(gPdh).