bluuebunny/crossref_metadata_2025_split huggingface dataset:
The correlations of sexual activity, sleep problems, emotional distress, attachment styles with quality of life: comparison between gynaecological cancer survivors and noncancer women
Authors: Hsieh Chia‐Chen , Chen Chi‐An , Hsiao Fei‐Hsiu , Shun Shiow‐Ching 
Published: May 2013

Aims and objectivesTo compare quality of life and its related factors, which include sexual activity, sleep problems, depression, anxiety and attachment styles in close relationships, between gynaecological cancer survivors and noncancer women.BackgroundThe majority of studies focus on examining the relationships between the late‐treatment side effects and quality of life in gynaecological cancer survivors. As a result, there is insufficient information about what are the correlations between psychosocial factors and quality of life in gynaecological cancer survivors.DesignCross‐sectional study.MethodsThe quality of life of the 85 gynaecological cancer patients who had completed active treatments for at least six months was compared with the 85 age‐matched women without cancer history. Measures included SF‐12 Health Surveys, Medical Outcomes Study Sleep Scale, Beck Depression Inventory‐II, State‐Trait Anxiety Inventory, Sexual Activity Questionnaire and Experiences in Close Relationships‐Revised.ResultsThere were no significant differences in the quality of life between gynaecological cancer survivors and noncancer women. However, higher attachment‐related anxiety in close relationship was the main factor associated with the lower physical quality of life in the gynaecological cancer survivor group. In contrast, older ages were correlated with lower physical quality of life in noncancer women. Anxiety level was the main factor associated with lower mental quality of life for both groups.ConclusionsDifferent from noncancer women, the psychosocial factor of insecure attachment in close relationships was the main factor associated with physical quality of life for gynaecological cancer survivors. Anxiety status was the common factor correlated with mental quality of life for cancer and noncancer women.Relevance to clinical practiceDeveloping psychosocial interventions focusing on secure attachment in close relationships and anxiety management could improve physical and mental components of quality of life among gynaecological cancer survivors.
Self‐reports of faulty parental attachments in childhood and criminal psychopathy in an adult‐incarcerated population: an integrative literature review
Authors: Bailey C. , Shelton D. 
Published: May 2013

Accessible summary
This study examined self‐reports of psychopathic offenders' childhood interactions with their parents to better understand what variables influence adult criminal psychopathy.
The findings showed that childhood separations, physical abuse and indifferent parenting styles were more prominent in self‐reports of incarcerated male psychopaths than with incarcerated males who were not psychopathic.
To better understand the worldview of the criminal psychopath, and the trajectory of psychopathy, there is a need for more studies that examine childhood interactions with parental figures as reported by the adult criminal psychopath.
AbstractDespite the high percentage of incarcerated psychopaths, few studies attempt to assess the past parent–child bonds of these individuals by asking them to report childhood attachments with their parents. Currently, there is limited data regarding common variables that contribute to a break in parent–child attachment and later adult criminal psychopathy. The data that presently exist concentrate on juvenile or community samples and do not explore the attachment variables that continue into adult criminal psychopathy. This paper presents the current literature regarding self‐reports of childhood attachment to parents as indicated by male‐incarcerated adult psychopaths compared with self‐reports of childhood attachment to parents as indicated by male‐incarcerated adult non‐psychopaths. Variables that influence a break in attachment between the offenders and their parents and suggestions for future clinical research are provided.
Mass flowering of the tropical tree Shorea beccariana was preceded by expression changes in flowering and drought‐responsive genes
Authors: Kobayashi Masaki J. , Takeuchi Yayoi , Kenta Tanaka , Kume Tomonori , Diway Bibian , Shimizu Kentaro K. 
Published: May 2013

AbstractCommunity‐level mass flowering, known as general flowering, which occurs in South‐East Asia at supra‐annual irregular intervals, is considered a particularly spectacular phenomenon in tropical ecology. Recent studies have proposed several proximate factors inducing general flowering, such as drought and falls in minimum temperature. However, limited empirical data on the developmental and physiological processes have been available to test the significance of such factors. To overcome this limitation and test the hypotheses that general flowering is triggered by the proposed factors, we conducted an ‘ecological transcriptome’ study of a mass flowering species, Shorea beccariana, comparing meteorological data with genome‐wide expression patterns obtained using next‐generation sequencing. Among the 98 flowering‐related genes identified, the homologs of a floral pathway integrator, SbFT, and a floral repressor, SbSVP, showed dramatic transcriptional changes before flowering, and their flowering functions were confirmed using transgenic Arabidopsis thaliana. Expression in drought‐responsive and sucrose‐induced genes also changed before flowering. All these expression changes occurred when the flowering‐inducing level of drought was reached, as estimated using data from the preceding 10 years. These genome‐wide expression data support the hypothesis that drought is a trigger for general flowering.
Haloferax volcanii archaeosortase is required for motility, mating, and C‐terminal processing of the S‐layer glycoprotein
Authors: Abdul Halim Mohd Farid , Pfeiffer Friedhelm , Zou James , Frisch Andrew , Haft Daniel , Wu Si , Tolić Nikola , Brewer Heather , Payne Samuel H. , Paša‐Tolić Ljiljana , Pohlschroder Mechthild 
Published: May 2013

SummaryCell surfaces are decorated by a variety of proteins that facilitate interactions with their environments and support cell stability. These secreted proteins are anchored to the cell by mechanisms that are diverse, and, in archaea, poorly understood. Recently published in silico data suggest that in some species a subset of secreted euryarchaeal proteins, which includes the S‐layer glycoprotein, is processed and covalently linked to the cell membrane by enzymes referred to as archaeosortases. In silico work led to the proposal that an independent, sortase‐like system for proteolysis‐coupled, carboxy‐terminal lipid modification exists in bacteria (exosortase) and archaea (archaeosortase). Here, we provide the first in vivo characterization of an archaeosortase in the haloarchaeal model organism Haloferax volcanii. Deletion of the artA gene (HVO_0915) resulted in multiple biological phenotypes: (a) poor growth, especially under low‐salt conditions, (b) alterations in cell shape and the S‐layer, (c) impaired motility, suppressors of which still exhibit poor growth, and (d) impaired conjugation. We studied one of the ArtA substrates, the S‐layer glycoprotein, using detailed proteomic analysis. While the carboxy‐terminal region of S‐layer glycoproteins, consisting of a putative threonine‐rich O‐glycosylated region followed by a hydrophobic transmembrane helix, has been notoriously resistant to any proteomic peptide identification, we were able to identify two overlapping peptides from the transmembrane domain present in the ΔartA strain but not in the wild‐type strain. This clearly shows that ArtA is involved in carboxy‐terminal post‐translational processing of the S‐layer glycoprotein. As it is known from previous studies that a lipid is covalently attached to the carboxy‐terminal region of the S‐layer glycoprotein, our data strongly support the conclusion that archaeosortase functions analogously to sortase, mediating proteolysis‐coupled, covalent cell surface attachment.
Ustilago maydis natural antisense transcript expression alters mRNA stability and pathogenesis
Authors: Donaldson Michael E. , Saville Barry J. 
Published: May 2013

SummaryUstilago maydis infection of Zea mays leads to the production of thick‐walled diploid teliospores that are the dispersal agent for this pathogen. Transcriptome analyses of this model biotrophic basidiomycete fungus identified natural antisense transcripts (NATs) complementary to 247 open reading frames. The U. maydis NAT cDNAs were fully sequenced and annotated. Strand‐specific RT‐PCR screens confirmed expression and identified NATs preferentially expressed in the teliospore. Targeted screens revealed four U. maydis NATs that are conserved in a related fungus. Expression of NATs in haploid cells, where they are not naturally occurring, resulted in increased steady‐state levels of some complementary mRNAs. The expression of one NAT, as‐um02151, in haploid cells resulted in a twofold increase in complementary mRNA levels, the formation of sense–antisense double‐stranded RNAs, and unchanged Um02151 protein levels. This led to a model for NAT function in the maintenance and expression of stored teliospore mRNAs. In testing this model by deletion of the regulatory region, it was determined that alteration in NAT expression resulted in decreased pathogenesis in both cob and seedling infections. This annotation and functional analysis supports multiple roles for U. maydis NATs in controlling gene expression and influencing pathogenesis.
Whose Time Is It? Understanding Clock-time Pacing and Event-time Pacing in Complex Innovations
Authors: Dougherty Deborah , Bertels Heidi , Chung Ken , Dunne Danielle D. , Kraemer Justin 
Published: May 2013

AbstractTime pacing, which refers to the regulation of intensity and direction of people's attention and effort, is central to innovation management. However, in a study of complex product innovation in pharmaceuticals, we find that time pacing is a major source of conflict between managers and scientists over innovation management. Our analysis of this tension reveals that two very different forms of time pacing operate in this complex innovation. Clock-time pacing, which gauges progress by the predictable passage of clock time, is used by strategic managers to reduce unnecessary exploration, focus on necessary questions, and speed up the execution of steps. Event-time pacing, which gauges progress by the unpredictable achievement of learning events, is used by the scientists to develop a deep understanding of how a drug might behave in the body against a disease, to focus on learning by asking many questions, and to integrate emergent results into plausible patterns. We identify four dimensions that differentiate clock-time pacing from event-time pacing, which drive the tension between the two. We summarize negative effects that this tension can have on innovation if left unaddressed, and then suggest ways to integrate clock-time pacing with event-time pacing. We also discuss implications for Chinese management.
Fermenting Impasse: Women's Critical Communities and Ecclesial Transformation
Authors: McManus Kathleen 
Published: May 2013

AbstractIntroduction (And Abstract)My reflections are rooted in the spiritual suffering of impasse experienced by women in today's Church. Against the background of Constance Fitzgerald's seminal article, “Impasse and Dark Night,” I will engage Edward Schillebeeckx's category of negative contrast experience in conjunction with what Beverly Lanzetta has named the via feminina to begin to envision what may be fermenting in this dark night. Then, moving from individual to communal contemplation, I will discuss the role of Critical Christian communities in Schillebeeckx's theology, with attention to his analysis of the cross-grained nature of Church history in which genuine tradition includes “breaks.” Finally, drawing on the experiences of “Circles of Women Seeking Wisdom” with which I am involved, I will examine how critical communities of women in the Church constitute a mysticism of resistance with potential for ecclesial transformation.
Training program for overweight prevention in the child's first year: Compilation and results
Authors: Dera‐de Bie Eveliene , Gerver Willem Jan , Jansen Maria 
Published: May 2013

AbstractThe current local overweight‐prevention protocols are not applied as intended by Dutch child healthcare physicians and nurses. The development of a training program for these practitioners, based on the Intervention Mapping framework, with the aim of improving overweight‐prevention in a child's first year, is described in this study. The needs assessment showed three program objectives to be relevant, namely improving: (i) awareness of the importance of early overweight‐prevention; (ii) the competence to discuss (the risk of) overweight with parents; and (iii) working systematically according to the overweight‐prevention protocol. A matrix was then created specifying the program objectives in terms of personal learning objectives and environmental change objectives, and appropriate strategies were identified. The results suggested that a more active tailored and structured change strategy improves knowledge and skills, in particular, which results in a better overall implementation of the overweight‐prevention protocol. This training program should help providers understand how the implementation of a protocol, such as the overweight‐prevention protocol, can be improved. Using the Intervention Mapping framework for systematic protocol implementation seems a valuable option.
Dualist Mental Causation and the Exclusion Problem
Authors: Kroedel Thomas 
Published: May 2013

AbstractThe paper argues that dualism can explain mental causation and solve the exclusion problem. If dualism is combined with the assumption that the psychophysical laws have a special status, it follows that some physical events counterfactually depend on, and are therefore caused by, mental events. Proponents of this account of mental causation can solve the exclusion problem in either of two ways: they can deny that it follows that the physical effect of a mental event is overdetermined by its mental and physical causes, or they can accept that the physical effect is overdetermined but claim that this is unproblematic because the case is sufficiently dissimilar to prototypical cases of overdetermination.
Photorespiratory compensation: a driver for biological diversity
Authors: Sage R. F. 
Published: May 2013

AbstractThis paper reviews how terrestrial plants reduce photorespiration and thus compensate for its inhibitory effects. As shown in the equation ϕ = (1/Sc/o)O/C, where ϕ is the ratio of oxygenation to carboxylation, Sc/o is the relative specificity of Rubisco, O is stromal O2 level and C is the stromal CO2 concentration, plants can reduce photorespiration by increasing Sc/o or C, or by reducing O. By far the most effective means of reducing ϕ is by concentrating CO2, as occurs in C4 and CAM plants, and to a lesser extent in plants using a glycine shuttle to concentrate CO2 into the bundle sheath. Trapping and refixation of photorespired CO2 by a sheath of chloroplasts around the mesophyll cell periphery in C3 plants also enhances C, particularly at low atmospheric CO2. O2 removal is not practical because high energy and protein investment is needed to have more than a negligible effect. Sc/o enhancement provides for modest reductions in ϕ, but at the potential cost of limiting the kcat of Rubisco. An effective means of decreasing ϕ and enhancing carbon gain is to lower leaf temperature by reducing absorbance of solar radiation, or where water is abundant, opening stomata. By using a combination of mechanisms, C3 plants can achieve substantial (>30%) reductions in ϕ. This may have allowed many C3 species to withstand severe competition from C4 plants in low CO2 atmospheres of recent geological time, thereby preserving some of the Earth's floristic diversity that accumulated over millions of years.
The evolutionary history ofTrichoptera (Insecta): A case of successful adaptation to life in freshwater
Authors: MALM TOBIAS , JOHANSON KJELL ARNE , WAHLBERG NIKLAS 
Published: May 2013

AbstractThe insect orderTrichoptera (caddisflies) forms the second most species‐rich monophyletic group of animals in freshwater. So far, several attempts have been made to elucidate its evolutionary history with both morphological and molecular data. However, none have attempted to analyse the time frame for its diversification. The order is divided into three suborders –Annulipalpia,Integripalpia and ‘Spicipalpia’. Historically, the most problematic taxon to place within the order is ‘Spicipalpia’, whose larvae do not build traditional cases or filtering nets like the majority of the caddisflies. They have previously been proposed to be the sister group of all otherTrichoptera or more advanced within the order, with equivocal monophyly and with different interordinal placements among various studies. In order to resolve the evolutionary history of the caddisflies as well as timing their diversification, we utilized fragments of three nuclear (carbamoylphosphate synthethase, isocitrate dehydrogenase andRNApolymeraseII) and one mitochondrial (cytochrome oxidaseI) protein coding genes, with 16 fossil trichopteran taxa used for time calibration. The ‘spicipalpian’ families are recovered as ancestral to all other caddisflies, though paraphyletic. We recover stable relationships among most families and superfamilies, resolving many previously unrecognized phylogenetic affinities amongst extant families. The origin ofTrichoptera is estimated to be around 234 Ma, i.e.Middle –LateTriassic.
Human resource assessment for scaling up VL active case detection in Bangladesh, India and Nepal
Authors: Naznin E. , Kroeger A. , Siddiqui N. A. , Sundar S. , Malaviya P. , Mondal D. , Huda M. M. , Das P. , Karki P. , Banjara M. R. , Dreesch N. , Gedik G. 
Published: May 2013

AbstractObjectivesTo determine whether medical staff at PHC level would have the time to take up additional activities such as 1‐day fever camps for active VL case detection.MethodsThis article assessed the workload of health staff of different professional categories working at health facilities in Bangladesh, India and Nepal. Data were collected from different sites in high endemic VL areas. The study population was the health staff of government health facilities at all levels. Workload indicators of staffing need (WISN) software were adopted to carry out the analysis of staff workload and their availability in the selected health facility. The WISN difference and WISN ratio for a particular health facility were calculated from actual staffing available and calculated staffing requirement.ResultsThe results showed a mixed picture of the availability of health workers. In most settings of Bangladesh and India, physicians with or without laboratory technicians would have time for active case detection. In Nepal, this would be performed by trained nurses and paramedical personnel.ConclusionIf all vacant posts were filled, active case detection could be performed more easily. The elimination programme can be scaled up with the current staffing levels in the endemic areas with some short training if and when necessary.
Cytologic appearance of retinal cells included in a fine‐needle aspirate of a meningioma around the optic nerve of a dog
Authors: Tvedten Harold , Hillström Anna 
Published: May 2013

AbstractA 6‐year‐old Wirehair Dachshund had a meningioma around the optic nerve that caused exophthalmos. A benign mesenchymal tumor was suspected based on the cytologic pattern of a fine‐needle aspirate, and a meningioma was diagnosed by histopathologic examination. In addition to the meningioma cells, the cytologic smears included groups of cells from apparently 4 layers of normal retina. In particular, uniform rod‐shaped structures in the cytologic sample could suggest rod‐shaped bacteria, but these structures were identified as cylindrical outer segments of photoreceptor rod cells. Other retinal structures recognized included pigmented epithelial layer cells with their uniquely formed pigment granules, the characteristic bi‐lobed, cleaved nuclei from the outer nuclear layer, and nerve tissue likely from the outer plexiform layer of the retina.
Assessment of blood types of Ragdoll cats for transfusion purposes
Authors: Proverbio Daniela , Spada Eva , Perego Roberta , Della Pepa Alessandra , Bagnagatti De Giorgi Giada , Baggiani Luciana 
Published: May 2013

BackgroundTransfusion of compatible blood types ensures the vitality of transfused erythrocytes and avoids transfusion reactions. Cats with types A, B, andABblood should receive transfusions of the same blood type. In a feline blood donor program, it is therefore essential to have blood donors of all blood types available.ObjectivesThe objectives of this study were the identification of the 3 feline blood types in Ragdoll cats, the comparison of their frequencies with those of Domestic Shorthair (DSH) cats, and the determination of whether Ragdolls are suitable donors in a feline blood donor program.MethodsThe blood type was determined by gel column agglutination from Ragdoll cats. The relationships between phenotypic traits, the origin of the cats, and the different blood types were examined. The frequencies for potential transfusion reactions and the risk for neonatal isoerythrolysis (NI) were estimated.ResultsOf 61 typed Ragdolls, 77.1% had type A, 4.9% type B, and 18% typeABblood. The frequency of blood type A in Ragdolls was lower than in DSH cats (P = .02), while the frequency of blood typeABin Ragdolls was higher than inDSHcats (P = .0002). No relationship was found between blood type and origin of the cat or phenotypic traits. The estimated frequencies of major and minor transfusion reactions following an unmatched transfusion between Ragdolls (donors and recipients), Ragdoll donors andDSHrecipients, andDSHdonors and Ragdoll recipients were 4.7%, 6.7%, 4.6%, and 18.5%, 20.8%, 7.6%, respectively. The frequency of kittens at risk forNIwas 5%.ConclusionThe presence of all 3 feline blood types and a relatively high incidence ofABtype cats make Ragdolls an ideal donor breed to include in feline blood transfusion programs.