bluuebunny/crossref_metadata_2025_split huggingface dataset:
Novel and simple prognostic index for nasal natural killer/T‐cell lymphoma
Authors: Hanakawa Hiroyuki , Orita Yorihisa , Sato Yasuharu , Takao Soshi , Marunaka Hidenori , Morishita Tokiwa , Yamashita Yasuhiko , Hori Yasutaka , Domae Shuhei , Inokuchi Ikuo , Akagi Seiko , Kondo Eisei , Iwaki Noriko , Motomiya Kana , Okumura Hirokazu , Yoshino Tadashi , Nishizaki Kazunori 
Published: June 2013

BackgroundFew studies have investigated the prognostic factors for nasal natural killer (NK)/T‐cell lymphoma.MethodsThis was a retrospective multicenter clinical study. The clinical records of 36 patients with nasal NK/T‐cell lymphoma who had been first treated between 1996 and 2011 were collected from 12 hospitals.ResultsHigh serum levels of C‐reactive protein (≥1.0 mg/dL), lactate dehydrogenase (≥350 IU/L), and soluble interleukin‐2 receptor (sIL‐2R; ≥600 U/mL) were associated with worse prognosis. A prognostic score was devised by totaling the number of these 3 predictors: 0 or 1 = score 0; and 2 or 3 = score 1. As for tumor invasion, local invasion beyond the nasal cavity was associated with poor prognosis, and a prognostic score was devised as: tumor restricted to nasal cavity, yes = score 0; no = score 1. A novel prognostic index (NPI) was established based on these scores from 0 to 2. Disease‐specific survival rates at 5 years were: 90.0% for NPI = 0; 29.3% for NPI = 1; and 0.0% for NPI = 2.ConclusionOur NPI is valid for anticipating prognosis of nasal NK/T‐cell lymphoma. © 2013 Wiley Periodicals, Inc. Head Neck 36: 551–556, 2014
Predictors of cervical lymph node metastasis in salivary gland cancer
Authors: Ettl Tobias , Gosau Martin , Brockhoff Gero , Schwarz–Furlan Stephan , Agaimy Abbas , Reichert Torsten E. , Rohrmeier Christian , Zenk Johannes , Iro Heinrich 
Published: June 2013

BackgroundThis study compares clinicopathological parameters with novel molecular markers for predicting cervical lymph node metastasis in salivary gland cancer.MethodsThree hundred sixteen salivary gland carcinomas were included in this study. Genomic epidermal growth factor receptor (EGFR), human epidermal growth factor receptor 2 (HER2), phosphatase and tensin homolog (PTEN), and hepatocyte growth factor receptor (MET) was determined by fluorescence in situ hybridization (FISH). Chi‐square tests, multivariate regression, and Kaplan–Meier survival analysis were used for statistics.ResultsNodal staging determines long‐term survival. Clinicopathological parameters associated with positive neck nodes are advanced age (p = .006), T3/T4 classification, histological high‐grade malignancy, and diagnosis of salivary duct carcinoma (p < .001 each). Neck node metastases also correlate with copy number gain of EGFR (p = .004) and HER2, aberration of MET, and deletion of PTEN (p < .001 each). Multivariate analysis showed SDC (p = .002) to be the strongest predictor of lymph node metastasis, followed by MET aberration (p = .009), T3/T4 classification (p = .017), PTEN deletion (p = .042), and adenocarcinoma not otherwise specified (NOS; p = .047).ConclusionThe histological subtype is crucial for decisions regarding neck dissection. New molecular parameters may also indicate elective treatment of the neck. © 2013 Wiley Periodicals, Inc. Head Neck 36: 517–523, 2014
Clinical and pathological characteristics of incidental and nonincidental papillary thyroid microcarcinoma in 339 patients
Authors: Vasileiadis Ioannis , Karatzas Theodore , Vasileiadis Dimitrios , Kapetanakis Stylianos , Charitoudis Georgios , Karakostas Efthimios , Kouraklis Gregory 
Published: June 2013

BackgroundWe analyzed the incidence and the clinicopathological characteristics of papillary thyroid microcarcinoma (PTMC) in a high prevalence region of goiter with the purpose to investigate differences between incidental and nonincidental PTMC.MethodsA total of 2236 patients who underwent total thyroidectomy from 2001 to 2009 were reviewed retrospectively. Papillary carcinoma was diagnosed in 583 patients. Of these, 339 patients with PTMC were included in the study. Clinicopathological features were evaluated by univariate and multivariate analysis.ResultsThe prevalence of incidental PTMC was 12% of all patients who underwent surgery for thyroid disease. Univariate analysis showed that bilaterality (p = .001), autoimmune thyroid disease (p = .049), size of tumor >5 mm (p < .001), multifocality (p < .001), lymph node metastasis (p < .001), and capsule invasion (p < .001) were significantly associated with nonincidental PTMC. The incidence of lymph node metastasis in incidental PTMC was 5% versus 33% in nonincidental, suggesting that the biological behavior may be different in the 2 categories.ConclusionOur results indicate that a high rate of PTMC presented 1 or more risk factors including multifocality, bilaterality, capsule invasion, and lymph node metastasis. Therefore, we suggest total thyroidectomy followed by adequate exploration of the central neck compartment for possible nodal involvement and resection as a safe therapeutic approach. © 2013 Wiley Periodicals, Inc. Head Neck 36: 564–570, 2014
Reconsidering the Shareholder's Role in Corporate Reorganisations under Insolvency Law
Authors: Madaus Stephan 
Published: June 2013

AbstractA corporate reorganisation under insolvency law is commonly achieved by virtue of a reorganisation plan that provides for the distribution and sacrifice of value among all stakeholders in an insolvent company. Although the creditors' right to vote on such plans and to participate in the wealth distribution according to such plans is universally accepted, the role of old equity in a corporate reorganisation remains a topic that jurisdictions all over the world define very differently. This article first explores possible approaches to shareholders' treatment under insolvency law and supports their inclusion in insolvency proceedings that pursue corporate reorganisations. It then argues that equity interest should not solely be treated according to its economic value and consequently that no absolute priority rule should be applied against them as such treatment would ignore the fundamental difference between liquidation and reorganisation. Finally, it proposes a new cram‐down rule for a class of equity holders. Copyright © 2013 INSOL International and John Wiley & Sons, Ltd.
Parenting Interactions with Children: Checklist of Observations Linked to Outcomes (PICCOLO) in Diverse Ethnic Groups
Authors: Roggman Lori A. , Cook Gina A. , Innocenti Mark S. , Jump Norman Vonda , Christiansen Katie 
Published: June 2013

ABSTRACTParenting interactions are important for children's early development, but existing observational measures of parenting are often difficult for practitioners to use in their work with parents and have been developed based on primarily European American middle‐income parents. Practitioners working with parents of infants and young children need a psychometrically strong observational measure of parenting behaviors appropriate for diverse groups. We tested the reliability and validity of 89 specific parenting behavior items by having observers rate over 4,500 viderecorded observations of parent–infant interaction from the archive of the Early Head Start Research and Evaluation Project and other research. These observations at multiple age points were from over 2,000 low‐icome families, including European Americans, African Americans, and Latino Americans. Interrater agreement was tested for each item. Scale internal consistency and single‐factor structure were tested within each of four domains—affection, responsiveness, encouragement, and teaching. Validity was tested with concurrent parenting measures and child development outcome measures. The 29 most consistently reliable and valid items comprise the final version of Parenting Interactions with Children: Checklist of Observations Linked to Outcomes (PICCOLO), an evidence‐based observational measure of parenting with very young children that is psychometrically sound and useful for practitioners working with diverse groups.
Families in Transition: From the Past into the Future
Authors: Cade Brian 
Published: June 2013

… what does education do, what does it have to offer, when deprived of its necessary partner, the future …?Graham Swift, Waterland (1992: 154)Myths are things that never occurred but always are.Sallustius… we should certainly pay far more attention to the biological theory of domination‐subordinance.This theory has sprung from the study of non‐human primates like gorillas ans chimpanzees. It has been discovered that their relative domination over or subordinance to one another depends largely on size and (outside the periods when females are on heat) non‐sexual factors akin to human self‐confidence. Thus a large female and a small male in the same cage will be respectively the dominator and the subordinate; the male will ‘present’ (adopt female copulatory positions) as a sign of submission. We must realise that all humans adopt (or veer between) one or other of these roles irrespective of sex.But of course human beings are not caged and live in far more complex situations; and it is the chainreaction aspect of this realtionship need that is the most dangerous for society.John Fowles, The Aristos (1968: 177–8).
Stages In Therapy For Men Whose Partners Do Not Enjoy Sex
Authors: Roughan Penny 
Published: June 2013

‘We live in a society in which we are continually told of our ‘right’ to sexuality; the new understanding which sees enjoyable sex as a right, not a privilege, of human beings (Health, 1982).This paper summarises some of the author's experiences in working with male partners of couples who present with sexual concerns. Patterns of progress are traced through four stages, labelled for convenience: engagement, withdrawal, ‘eureka’ and balance. These stages evolve as the man moves from patriarchal assumptions about performance and entitlement towards a more truly mutual sexual interaction with his partner.
Diagnostic accuracy of two questionnaires for the detection of neuropathic pain in the Spanish population
Authors: Hamdan A. , Luna J.D. , Del Pozo E. , Gálvez R. 
Published: June 2013

AbstractBackgroundSeveral questionnaires have been developed for the detection of neuropathic pain.ObjectivesThis study aimed to compare the diagnostic accuracy of the Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) pain scale and the Douleur Neuropathique en 4 questions (DN4) questionnaire for the detection of peripheral neuropathic pain in the Spanish population, and to analyse in detail the diagnostic quality of each item in these questionnaires.MethodsA total of 192 patients were enrolled. We compared the validity of the DN4 and LANSS questionnaires by studying sensitivity and specificity and using receiver operating characteristic (ROC) curve analysis. We also analysed the validity of each item in the questionnaires.ResultsThe sensitivity of the DN4 questionnaire with an accepted cut‐off value of ≥4 was 95.04% and that of the LANSS questionnaire with an accepted cut‐off value of ≥12 was 80.17%. The specificity of the DN4 instrument was 97.18% and that of the LANSS instrument was 100%. The estimated area under the ROC curve (95% confidence interval) was 0.989 (0.977–1) for the DN4 instrument and 0.973 (0.956–0.991) for the LANSS questionnaire. The area under the ROC curve was significantly larger for the DN4 than the LANSS questionnaire (p < 0.05). Analyses of specific items showed that tingling and numbness in the DN4 tool, and light touch pain and altered pinprick threshold in the LANSS scale, were the most important features of neuropathic pain.ConclusionsThese results show that although both questionnaires are good screening tools, the DN4 questionnaire is particularly recommended for identifying patients with neuropathic pain in clinical practice and research studies.
The Role of Therapeutic Alliance in Mindfulness Interventions: Therapeutic alliance in Mindfulness Training for Smokers
Authors: Goldberg Simon B. , Davis James M. , Hoyt William T. 
Published: June 2013

ObjectiveMindfulness‐based interventions have enjoyed a marked increase in support within biomedical and psychological research and practice in the past two decades. Despite the widespread application of these treatments for a range of psychological and medical conditions, there remains a lack of consensus regarding mechanisms through which these interventions effect change. One plausible yet underexplored mechanism is the therapeutic alliance between participants and mindfulness instructors.MethodsIn this report, data are presented on therapeutic alliance from the mindfulness arm (n = 37) of a randomized controlled trial of a mindfulness‐based smoking cessation treatment.ResultsResults suggest that client‐reported therapeutic alliance measured midtreatment did not significantly predict primary smoking outcomes. Alliance did predict improvement in posttreatment scores on several outcome variables linked to mindfulness practice, including emotion regulation (β = −.24, p = .042), mindfulness (β = .33, p = .007), negative affect (β = −.33, p = .040), as well as treatment compliance (β = .39, p = .011).ConclusionImplications of these relationships and the possible role of therapeutic alliance in mindfulness treatments are explored.
Factor Structure of the CES‐D and Measurement Invariance Across Gender in Mainland Chinese Adolescents
Authors: Wang Mengcheng , Armour Cherie , Wu Yan , Ren Fen , Zhu Xiongzhao , Yao Shuqiao 
Published: June 2013

ObjectivesThe primary aim was to examine the depressive symptom structure of Mainland China adolescents using the Center for Epidemiologic Studies Depression Scale (CES–D).DesignExploratory factor analysis (EFA) and confirmatory factor analysis (CFA) were simultaneously conducted to determine the structure of the CES‐D in a large scale, representative adolescent samples recruited from Mainland China. Multigroup CFA (N = 5059, 48% boys, mean = 16.55±1.06) was utilized to test the factorial invariance of the depressive symptom structure, which was generated by EFA and confirmed by CFA across gender.ResultsThe CES‐D can be interpreted in terms of 3 symptom dimensions. Additionally, factorial invariance of the new proposed model across gender was supported at all assuming different degrees of invariance.ConclusionMainland Chinese adolescents have specific depressive symptom structure, which is consistent across gender.
New proposal for response‐guided peg‐interferon‐plus‐ribavirin combination therapy for chronic hepatitis C virus genotype 2 infection
Authors: Abe Hiroshi , Aida Yuta , Ishiguro Haruya , Yoshizawa Kai , Seki Nobuyoshi , Miyazaki Tamihiro , Itagaki Munenori , Sutoh Satoshi , Ika Makiko , Kato Keizo , Shimada Noritomo , Tsubota Akihito , Aizawa Yoshio 
Published: June 2013

AbstractThis study aimed to determine the most suitable duration of pegylated‐interferon (Peg‐IFN)‐plus‐ribavirin combination therapy in patients infected with hepatitis C virus (HCV) genotype 2 who had not achieved rapid virological response (serum HCV RNA disappearance after 4 weeks of therapy). HCV genotype 2 patients (n = 182) with a high viral load received >80% of the standard Peg‐IFN‐plus‐ribavirin dose for at least 24 weeks, and their final virological responses were studied. Patients were classified into “rapid virological response” and “non‐rapid virological response” groups. The non‐rapid virological response group was further divided into a “virological response at 8 weeks” (serum HCV RNA disappearance after 8 weeks of therapy) and a “non‐virological response at 8 weeks” group. Factors related to rapid virological response and optimal therapy duration in the non‐rapid virological response group were evaluated. Multivariate logistic regression analysis showed that subtype HCV genotype 2a (P = 0.0015) and low concentration of pretreatment serum HCV RNA (P = 0.0058) were independent factors in a rapid virological response. In the virological response at 8 weeks group, the sustained virological response rate after 24 weeks of therapy was significantly lower than after 36 weeks (P = 0.044) or after 48 weeks (P = 0.006), and was similar for 36‐ and 48‐weeks. The cost for achieving (CAS) one sustained virological response was lowest with 36‐week therapy. Prolongation of Peg‐IFN‐plus‐ribavirin combination therapy to 36 weeks is suitable for achieving virological response at 8 weeks, given the high, sustained virological response rate and cost benefit. J. Med. Virol. 85:1523–1533, 2013. © 2013 Wiley Periodicals, Inc.
Molecular characterization of human respiratory syncytial virus NA1 and GA5 genotypes detected in Assam in northeast India, 2009–2012
Authors: Biswas Dipankar , Yadav Kaushal , Borkakoty Biswajyoti , Mahanta Jagadish 
Published: June 2013

AbstractA significant number of children die each year from acute respiratory tract infections especially in developing countries. Human respiratory syncytial virus (RSV) is the most common virus identified in such cases. Genetic characterization and the circulation pattern of RSV is important for future selection of appropriate vaccine strains. Limited information is available on the circulation of RSV in developing countries including India. The present study aimed to provide baseline information on the genetic variability of RSV in the Dibrugarh district of Assam, northeast India. Clinical specimens collected from children aged ≤6 years for routine influenza surveillance in the Dibrugarh district of Assam during the period 2009–2012, were screened for RSV by real‐time reverse transcription‐polymerase chain reaction. Genotyping was based on partial sequencing of the RSV attachment glycoprotein gene. RSV was detected in 7.9% (39/493) of cases. Only RSV group A viruses were detected during the study period with predominance of NA1 genotypes (89%). Two RSV GA5 genotypes were found to be co‐circulating during 2012. The specific amino acid substitutions characteristics of the NA1 genotypes were distinct from RSV strains reported from the rest of India. It is concluded that the circulating genotypes of RSV in Assam, northeast India are NA1 and GA5. To our knowledge this is the first report of circulation of the NA1 genotype in India. J. Med. Virol. 85:1639–1644, 2013. © 2013 Wiley Periodicals, Inc.
Hepatitis C virus infection in the Maghreb region
Authors: Ezzikouri Sayeh , Pineau Pascal , Benjelloun Soumaya 
Published: June 2013

ABSTRACTHepatitis C is a global health problem with a worldwide prevalence of about 3% (around 170 million people). Hepatitis C virus (HCV) is major concern in the Maghreb countries, Algeria, Libya, Mauritania, Morocco, and Tunisia, but no detailed description of its epidemiology in the region is available. In the present review, a systematic search was undertaken covering HCV data available in peer‐reviewed databases as well as institutional reports and regional conference meeting abstracts from the Maghreb countries. Reports written in English and French were included in this analysis. Estimates of national and regional prevalence of HCV infection (based on anti‐HCV antibody) and of the size of patient populations were performed. In addition, the molecular features of the circulating viral strains in the region are discussed. A substantial proportion, 1.2–1.9% of the Maghreb inhabitants, have anti‐HCV antibodies. Genotype 1b predominates among viral strains in all countries except in Libya, where genotype 4 is dominant as in neighboring Egypt. This epidemiological situation is of significant concern, and requires urgent, broad, and active intervention for the prevention and control of HCV. More specifically, the application of state‐of‐the‐art hygiene procedures and rigorous controls in medical disciplines such as hemodialysis, transfusion, endoscopic procedures, and dentistry is necessary to reduce significantly the number of new infections in the region. J. Med. Virol. 85:1542–1549, 2013. © 2013 Wiley Periodicals, Inc.
Future convective environments using NARCCAP
Authors: Gensini Vittorio A. , Ramseyer Craig , Mote Thomas L. 
Published: June 2013

ABSTRACTThis study examines trends in atmospheric environments conducive to the development of severe convection in the United States, as simulated by a regional model forced with output from a global climate model. Meteorological variables necessary for severe convection from current (1981–1995) and future (2041–2065) epochs were compared. Results indicate a statistically significant increase in the number of significant severe weather environments in the Northeast United States, Great Lakes, and Southeast Canada regions. Regional severe weather environment increases can be attributed to both an increase in convective available potential energy (CAPE) and the number of times deep‐layer wind shear and CAPE juxtaposition. Given the current distribution of severe convective weather, these changes would alter the current physical risk of severe convective storms across a large population.
Inkjet Approaches Contribute to Facile Isotactic Poly(Methyl)/Syndiotactic Poly(Methyl Methacrylate) Stereocomplex Surface Preparation
Authors: Ajiro Hiroharu , Hinoue Tomoaki , Akashi Mitsuru 
Published: June 2013

AbstractIsotactic poly(methyl methacrylate) and syndiotactic poly(methyl methacrylate) form a stereocomplex using an inkjet system. As compared with conventional methods such as simply mixing solutions or dipping substrates with a layer‐by‐layer (LbL) approach, a much smaller amount of polymer chains (9.0 × 107) can theoretically associate with each other, and the process is quicker. Glass and polystyrene substrates are compared as substrates, suggesting different morphologies due to the solvent interactions during the rapid evaporation. The stereocomplex structure is confirmed by infrared spectroscopy and X‐ray diffraction.magnified image
Photoinitiator‐Free, Open‐Air Acceptor/Donor Copolymerization of Bismaleimides: Simple Polymerization Conditions for New Thermoplastic Elastomer Production
Authors: Vázquez Cuauhtémoc Pozos , Joly‐Duhamel Christine , Boutevin Bernard 
Published: June 2013

AbstractA photoinitiator‐free acceptor–donor copolymerization between a mixture of bismaleimides containing oligo(propyleneglycol)s as acceptor monomers and divinyl ether as the donor monomer under UV is described. The copolymerization without any photoinitiator is faster than homopolymerization of the sole maleimide, thanks to an acceptor–donor charge‐transfer complex. The thermal and mechanical properties of the cured materials depend essentially on the cross‐linking densities and on the number of repeated units in the bismaleimide backbone. Most copolymerizations produce elastomers with remarkable rubbery properties on a large temperature scale. The simple chemistry presented here can easily compete with acrylate photochemistry since neither photoinitiator nor oxygen removal is needed.magnified image