bluuebunny/crossref_metadata_2025_split huggingface dataset:
Everyday Life of Young Adults With Intellectual Disabilities: Inclusionary and Exclusionary Processes Among Young Adults of Parents With Intellectual Disability
Authors: Starke Mikaela 
Published: July 2013

Abstract
Ten young adults with an intellectual disability whose parents, too, have an intellectual disability were interviewed and completed questionnaires for this exploratory study aimed at charting their experiences of everyday life. Most of the participants reported high life satisfaction, especially with the domains of friends, leisure time, and family, and considered their families as a resource for their empowerment and development of resilience. The study participants' informal networks were composed of only a few individuals who, moreover, were mostly of dissimilar age and also included support professionals. The participants typically described themselves as excluded from others, an experience that was articulated most conspicuously in their narratives about the special schools they were attending.
Transferring Young People With Profound Intellectual and Multiple Disabilities From Pediatric to Adult Medical Care: Parents' Experiences and Recommendations
Authors: Bindels-de Heus Karen G. C. B. , van Staa AnneLoes , van Vliet Ingeborg , Ewals Frans V. P. M. , Hilberink Sander R. 
Published: July 2013

AbstractMany children with profound intellectual and multiple disabilities (PIMD) now reach adulthood. The aim of this study was to elicit parents' experiences with the transfer from pediatric to adult medical care. A convenience sample of 131 Dutch parents of young people with PIMD (16–26 years) completed a web-based questionnaire. Twenty-two percent of the young persons were still in pediatric care; 22% of the others had no care coordinator, although their health needs were the same. Parents valued the care provided by the pediatrician, and wished to see it continued. They were critical about how they had been prepared for transfer to adult care. Parents provided suggestions to improve transitional care, such as early start, information provision, and a joint consultation between pediatric and adult care.
Interactions Between Turkish Mothers and Preschool Children With Autism
Authors: Diken Ozlem , Mahoney Gerald 
Published: July 2013

AbstractThis study explored the relationship between Turkish mothers' style of interaction and the engagement of their preschool-aged children with autism. Data were collected from fifty mother–child dyads in which all children had diagnoses of autism. Video recordings of mother–child interaction were analyzed using the Turkish versions of the Maternal Behavior Rating Scale and the Child Behavior Rating Scale (O. Diken, 2009). Similar to mothers from Western countries, Turkish mothers tended to engage in highly directive interactions with their children. However, a cluster analysis revealed considerable variability in mothers' style of interaction. This included a directive nonengaged style, a directive/achievement-oriented style, and a responsive style of interaction. Children's level of engagement was associated with differences in mothers' style of interaction. Children were least engaged with directive/nonengaged mothers and most engaged with responsive mothers. However, children's engagement was only associated with their mothers' responsiveness, not with their directiveness. Results are discussed in terms of their implications for early intervention.
Zinc-Modified MCM-22 as Potential Solid acid Catalyst for Friedel–Crafts Alkylation Reaction
Authors: V. Lande Sharad , Sakthivel, A. , Murthy K. V. V. S. B. S. R. , Sreedharan Unnikrishnan , Das Jagannath , Vir Jasra Raksh 
Published: July 2013

Abstract
In this paper, we report loading of ZnCl2 on microporous medium pore high surface area zeolite, which was achieved by incipient wetness method. The zinc-modified mobil composite material
-22 (Zn-MCM-22) was systematically characterized by powder X-ray diffraction, N2 adsorption-desorption analysis, scanning electron microscopy and Fourier transform infrared spectroscopy. The acidity of the materials was studied by temperature programmed desorption of ammonia analysis. The well-characterized Zn-MCM-22 catalyst was investigated for the Friedel–Crafts alkylation of benzene by benzyl chloride in liquid phase medium. A systematic investigation of various operating parameters like effect of different temperature, catalyst loading and reactant molar ratio was carried out. The Zn-MCM-22 found to be promising, further the catalytic activity remains stable over several recycles.
Mutation Rates, Spectra, and Genome-Wide Distribution of Spontaneous Mutations in Mismatch Repair Deficient Yeast
Authors: Lang Gregory I , Parsons Lance , Gammie Alison E 
Published: July 2013

Abstract
DNA mismatch repair is a highly conserved DNA repair pathway. In humans, germline mutations in hMSH2 or hMLH1, key components of mismatch repair, have been associated with Lynch syndrome, a leading cause of inherited cancer mortality. Current estimates of the mutation rate and the mutational spectra in mismatch repair defective cells are primarily limited to a small number of individual reporter loci. Here we use the yeast Saccharomyces cerevisiae to generate a genome-wide view of the rates, spectra, and distribution of mutation in the absence of mismatch repair. We performed mutation accumulation assays and next generation sequencing on 19 strains, including 16 msh2 missense variants implicated in Lynch cancer syndrome. The mutation rate for DNA mismatch repair null strains was approximately 1 mutation per genome per generation, 225-fold greater than the wild-type rate. The mutations were distributed randomly throughout the genome, independent of replication timing. The mutation spectra included insertions/deletions at homopolymeric runs (87.7%) and at larger microsatellites (5.9%), as well as transitions (4.5%) and transversions (1.9%). Additionally, repeat regions with proximal repeats are more likely to be mutated. A bias toward deletions at homopolymers and insertions at (AT)n microsatellites suggests a different mechanism for mismatch generation at these sites. Interestingly, 5% of the single base pair substitutions might represent double-slippage events that occurred at the junction of immediately adjacent repeats, resulting in a shift in the repeat boundary. These data suggest a closer scrutiny of tumor suppressors with homopolymeric runs with proximal repeats as the potential drivers of oncogenesis in mismatch repair defective cells.
The Developmental Transcriptome of the Mosquito Aedes aegypti, an Invasive Species and Major Arbovirus Vector
Authors: Akbari Omar S , Antoshechkin Igor , Amrhein Henry , Williams Brian , Diloreto Race , Sandler Jeremy , Hay Bruce A 
Published: July 2013

Abstract
Mosquitoes are vectors of a number of important human and animal diseases. The development of novel vector control strategies requires a thorough understanding of mosquito biology. To facilitate this, we used RNA-seq to identify novel genes and provide the first high-resolution view of the transcriptome throughout development and in response to blood feeding in a mosquito vector of human disease, Aedes aegypti, the primary vector for Dengue and yellow fever. We characterized mRNA expression at 34 distinct time points throughout Aedes development, including adult somatic and germline tissues, by using polyA+ RNA-seq. We identify a total of 14,238 novel new transcribed regions corresponding to 12,597 new loci, as well as many novel transcript isoforms of previously annotated genes. Altogether these results increase the annotated fraction of the transcribed genome into long polyA+ RNAs by more than twofold. We also identified a number of patterns of shared gene expression, as well as genes and/or exons expressed sex-specifically or sex-differentially. Expression profiles of small RNAs in ovaries, early embryos, testes, and adult male and female somatic tissues also were determined, resulting in the identification of 38 new Aedes-specific miRNAs, and ~291,000 small RNA new transcribed regions, many of which are likely to be endogenous small-interfering RNAs and Piwi-interacting RNAs. Genes of potential interest for transgene-based vector control strategies also are highlighted. Our data have been incorporated into a user-friendly genome browser located at www.Aedes.caltech.edu, with relevant links to Vectorbase (www.vectorbase.org)
Transoral C2 biopsy and vertebroplasty
Authors: Kaminsky Ian A. , Härtl Roger , Sigounas Dimitri , Mlot Stefan , Patsalides Athos 
Published: July 2013

Abstract
Pathologic fractures involving the C2 vertebral body and odontoid process pose a unique dilemma, as the surgical approach for direct odontoid process screw fixation has several limitations. There have been a small number of transoral approach C2 vertebroplasty or kyphoplasty reported in the literature. Previous attempts were performed utilizing fluoroscopy or CT guidance. We report a case of a fluoroscopically guided transoral approach vertebroplasty in a patient with a lytic lesion involving the C2 vertebral body, extending into the odontoid process with an underlying pathologic fracture. This case is unique as two separate punctures were required in order to adequately stabilize the pathologic fracture, CTA was performed preoperatively to better evaluate regional vasculature, and a post-procedure rotational flat panel CT was performed to assess cement placement.
Skin-to-Skin Contact Diminishes Pain From Hepatitis B Vaccine Injection in Healthy Full-Term Neonates
Authors: Kostandy Raouth , Anderson Gene C. , Good Marion 
Published: July 2013

AbstractPurpose: This study was conducted to test the hypothesis that skin-to-skin contact (SSC) would reduce hepatitis B vaccine injection pain in full-term neonates.Design: Randomized controlled trial (RCT).Sample: Thirty-six mother–neonate dyads were randomly assigned to SSC or control groups.Main Outcomes: Cry time (CT), behavioral state (BSt), and heart rate (HR) were measured throughout the 16-minute protocol. HR and BSt were measured every 30 seconds; CT was recorded continuously.Results: SSC neonates cried less compared with controls (23 vs 32 seconds during injection; 16 vs 72 seconds during recovery), reached calmer BSts sooner (M = 2.8 vs M = 6.5 time points), and trended toward more rapid HR decrease. SSC as described was safe and effective and merits further testing.
Corticotomy-assisted molar protraction with the aid of temporary anchorage device
Authors: Uribe Flavio , Janakiraman Nandakumar , Fattal Amine N. , Schincaglia Gian Pietro , Nanda Ravindra 
Published: July 2013

ABSTRACT
This case report describes the interdisciplinary management of a 58-year-old woman who was missing lower first molars and supraerupted maxillary first molars. The treatment plan included intrusion of the upper first molars and corticotomy-assisted mandibular second molar protraction with the aid of temporary anchorage devices. Miniscrews were effective in intrusion of the maxillary first molars and protraction of the lower second molars. Although good functional outcome was achieved in 41 months, the corticotomy-assisted procedure did not significantly reduce the treatment time.
A queer geography of a school
Authors: Freitag Mel 
Published: July 2013

What does it mean to queer a schooled space? When queers are physically visible in schools, how does that change the power relations and relationships within it? Researchers in the field of Human Geog-raphy have explored physical spaces that are “queered” – the gay ghettos – such as the gay bar, neighborhood, or city. While celebrating these gay spaces, and markers such as the safe space triangle sticker that allies in schools in the USA utilize to mark their offices as places where LGBTQ (lesbian, gay, bisexual, transgender, queer/questioning) students can “go” to feel comfort-able, or at least not bullied, that does not always mean that queers feel safe(r) in those spaces. Also, if one space is marked safe, what happens to the other unsafe spaces? Do they stay intact, and if so, is that to the detriment of all students? Therefore, it is imperative also to define what a safe or safe(r) space is, and then why they should exist at all. According to a recent nationwide survey conducted by Joseph Kosciw, Emily Greytak, and Elizabeth Diaz, nine out of ten LGBTQ-identified youth state they have been harassed and bullied in their schools. This is unacceptable.
One option in particular for queer subjects is to construct, live, and utilize these “queered” cities, neighborhoods, and schools. A physi-cally separated “gay space” could be a countersite for other, more privileged landscapes and narratives. For example, geographer Dereka Rushbrook takes Michel Foucault’s idea of “heterotopias” and defines it as “places that hold what has been displaced while serving as sites of stability for the displaced”, which I will use as a framework in this article. Much of the literature on queer geography has been on isolated or commercialized spaces, neighborhoods, cities, workplaces, bath houses, media, drag shows, sex workers, and more recently on immigration, transnational politics, public health, and globalization. The level of inclusivity of a school, for example, is traditionally a space that holds potential economic and social power for underrepresented students, including but not limited to queer-identified individuals.
Sportivisation des arts martiaux et contexte sociopolitique. Le cas du pencak silat en Indonésie
Authors: de Grave Jean-Marc 
Published: July 2013

À travers l’histoire des fédérations indonésienne et internationale de pencak silat , l’article décrit la politique d’État de l’Indonésie vis-à-vis des pratiques traditionnelles régionalement marquées de cet art martial. Dans cette politique, les Javanais représentent le groupe dominant et ils apparaissent comme étant au cœur de la dynamique instaurée. Ceci a pour effet d’instaurer des tensions avec certains groupes socioculturels minoritaires. Les réseaux internationaux qui soutiennent le développement de cet art martial jouent également un rôle. Ils se présentent notamment comme un contrepoids à la volonté marquée des cadres fédéraux d’établir des règles de compétition axées sur le combat au détriment de la gestuelle esthétique originale. Les sources utilisées sont des documents de travail ou de diffusion des fédérations, récoltés à l’occasion d’enquêtes menées depuis 1987. L’analyse tient aussi compte des entretiens avec des responsables de fédérations et d’écoles, ainsi que l’expérience de terrain ethnographique d’étude des pratiques et du fonctionnement des écoles de pencak silat . Il en ressort que c’est le processus de sportivisation que l’État indonésien a mis en avant au détriment des dimensions rituelle et religieuse. J’interprète ce processus – concomitant à celui de modernisation – comme participant de l’hégémonie de groupes d’influence (Javanais ; pro-sportivisation) sur d’autres (autres groupes ethniques ; ceux pour qui la version sportive dénature l’art martial).
Pour une conception linguistique des apprentissages en EPS. Mais à quel jeu jouent nos élèves ?
Authors: Louis Fabrice 
Published: July 2013

Dans cet article, nous focalisons notre attention sur deux piliers de l’éducation : l’apprentissage d’une langue et l’exercice de la citoyenneté par le partage des règles. Une des spécificités de l’EPS réside dans la possibilité qu’ont les enseignants de construire avec les élèves une « forme de vie », faite d’actions adaptées à une pratique physique qui s’apparente à un nouveau « jeu de langage ». Pour développer cette perspective linguistique issue du tournant grammatical dans la philosophie de Wittgenstein, nous adoptons l’anthropologie comme méthode d’identification des contenus d’apprentissage. Nous invitons le lecteur à percevoir les difficultés de l’enseignement en EPS comme des problèmes liés au fait que le sens de nos actions est institué socialement. Comme l’écrit Wittgenstein (2009, p. 274) : « Un jeu, un langage, une règle sont des institutions. » Or cette institutionnalisation agit à la fois comme une ressource et comme une contrainte car elle opère un tri entre ce qui a du sens et ce qui n’en a pas pour celui qui pratique une activité physique sportive et artistique. Les conséquences liées à cette perspective sont multiples (évolution du contrat didactique, des contenus, de l’évaluation...) et laissent entrevoir la possibilité d’une transversalité des apprentissages.
Schistosomiasis Causes Remodeling of Pulmonary Vessels in the Lung in a Heterogeneous Localized Manner: Detailed Study
Authors: Kolosionek Ewa , King Jayne , Rollinson David , Schermuly Ralph Theo , Grimminger Friedrich , Graham Brian B. , Morrell Nicholas , Butrous Ghazwan 
Published: July 2013

Schistosomiasis is a global parasitic disease with high impact on public health in tropical areas. Schistosomiasis is a well‐described cause of pulmonary arterial hypertension (PAH). The exact pathogenesis is still unclear, though inflammatory mechanisms are suspected. Another unknown is whether the changes in the pulmonary vasculature are generalized or localized. We studied 13 mice infected with cercariae for 12 weeks compared with 10 control mice. In our model, we observed that the liver was a target during infection and was enlarged more than two‐fold after infection. However, right heart hypertrophy as measured by RV/(LV + S) ratio was not observed at this time point. Moreover, we noticed that 72% of the sampled lobes (92% of the lungs) harvested from these animals costained evidence of granulomatous changes, secondary to egg deposition. We systemically mapped the distribution of granulomatous lesions in right lung lobes (n = 43) of infected mice. We observed that the distribution of the granulomatous lesions was heterogeneous. Remodeled pulmonary vessels were seen in 26% of the lobes (46% of the lungs) and were observed only in close proximity to the granuloma. No remodeling was observed in the absence of granulomas. These findings support the view that pulmonary vascular remodeling is caused by the local presence of granulomas in PAH associated with schistosomiasis. The heterogeneous nature of the remodeling partly explains why many patients with schistosomiasis do not develop pulmonary hypertension.
Persistent Pulmonary Artery Hypertension in Patients Undergoing Balloon Mitral Valvotomy
Authors: Nair Krishna Kumar Mohanan , Pillai Harikrishnan Sivadasan , Titus Thomas , Varaparambil Ajitkumar , Sivasankaran Sivasubramonian , Krishnamoorthy Kavassery Mahadevan , Namboodiri Narayanan , Sasidharan Bijulal , Thajudeen Anees , Ganapathy Sanjay , Tharakan Jaganmohan 
Published: July 2013

Pulmonary artery pressure (PAP) is known to regress after successful balloon mitral valvotomy (BMV). Data of persistent pulmonary artery hypertension (PPAH) following BMV is scarce. We analyzed the clinical, echocardiographic, and hemodynamic data of 701 consecutive patients who have undergone successful BMV in our institute from 1997 to 2003. Data of 287 patients who had PPAH (defined by pulmonary artery systolic pressure [PASP] of ≥ 40 mmHg at one year following BMV) were compared to the data of 414 patients who did not have PPAH. Patients who had PPAH were older (39.9 ± 9.9 years vs. 29.4 ± 10.1; P < 0.001). They had higher prevalence of atrial fibrillation (AF; 21.9 vs. 12.1%, P < 0.05), moderate or severe pulmonary artery hypertension (PAH) defined as PASP more than 50 mmHg (43.5 vs. 33.8%, P = 0.00), anatomically advanced mitral valve disease as assessed by Wilkin's echocardiographic score > 8 (33.7 vs. 23.2%, P < 0.001), and coexistent aortic valve disease (45.6 vs. 37.9%, P < 0.001) at the baseline. Those patients with PPAH had comparatively lower immediate postprocedural mitral valve area (MVA). On follow‐up of more than five years, the occurrence of restenosis (39.3 vs. 10.1%, P = 0.000), new onset heart failure (14% vs. 4%, P < 0.05) and need for reinterventions (9.5% vs. 2.8%, P < 0.05) were higher in the PPAH group. Patients with PPAH were older, sicker, and had advanced rheumatic mitral valve disease. They had higher incidence of restenosis, new onset heart failure, and need for reinterventions on long term follow‐up. PPAH represents an advanced stage of rheumatic valve disease and indicates chronicity of the disease, which may be the reason for the poorer prognosis of these patients. Patients with PPAH requires intense and more frequent follow‐up.
Clinical Evaluation of Dental Metal Hazards and Therapeutic Effects of Shortwave Diathermy in Dental Medicine
Authors: Mukai Chisato , Nakamoto Tetsuji , Kondo Yusuke , Masaki Chihiro , Ohta Atsumi , Hosokawa Ryuji 
Published: July 2013

ABSTRACT

Objective
Shortwave diathermy causes increase in temperature from deep inside the body, results in upregulation of metabolism, and has analgesic effects. In this study, we explored the potential application of shortwave diathermy in the maxillofacial region by monitoring internal and external temperature changes, changes in blood flow, and resting saliva secretion under shortwave diathermy for subjects with and without dental metal restorations (MR) to confirm the safety and the limitation of shortwave diathermy for dental medicine.

Materials and methods
Twenty young healthy subjects were recruited (10 subjects with MR and 10 subjects without MR). Shortwave exposure was achieved with condenser-type probes placed on the bilateral mandibular angles, and the intraoral temperature was monitored. For functional analysis, unstimulated whole saliva before and after exposure was collected. The temperature and blood flow distributions of the exposed areas were then monitored by thermography and twodimensional (2D) laser Doppler flowmetry.

Results
Shortwave exposure for 20 minutes induced significant temperature increases in all groups (p ≤ 0.05). The subjects reported no discomfort. When subjects without MR held gold or titanium crowns in their mouths, the thermal effect by shortwave diathermy was reduced. Resting saliva upon exposure only increased significantly in metal-free subjects, and amylase concentration was also increased, but the level of the salivary stress biomarker chromogranin A was unchanged. Furthermore, thermography showed that shortwave diathermy significantly increased the surface temperature for cheek skin and the buccal mucosa; however, this increase failed to elevate surface blood flow.

Conclusion
Shortwave diathermy induces temperature increases in the maxillofacial region. MR did not cause excessive heating, on the contrary, reduce the thermal effect of shortwave radiation. The temperature rise maintains upregulation in salivary function, which could be utilized safely in dental medicine.

How to cite this article
Mukai C, Nakamoto T, Kondo Y, Masaki C, Ohta A, Hosokawa R. Clinical Evaluation of Dental Metal Hazards and Therapeutic Effects of Shortwave Diathermy in Dental Medicine. Int J Prosthodont Restor Dent 2012;2(3): 88-95.