bluuebunny/crossref_metadata_2025_split huggingface dataset:
Microwave assisted water extraction of plant compounds
Authors: Flórez Noelia , Conde Enma , Domínguez Herminia 
Published: August 2014

AbstractThe development of environmentally friendly processes with limited generation of polluting streams to attain sustainable utilization of raw materials is encouraged. The implementation of novel extraction technologies more efficient, selective and with lower energy consumption than conventional ones, can help in achieving this objective. Particularly promising are aqueous based methods, since water is a cheap, safe and abundant solvent and the limited use of toxic organic solvents is a consumer's, ecological and processing demand. The benefits and the limiting aspects of microwave assisted water extraction, either adding water as the only solvent or in solvent free processes, using the naturally present water in vegetal materials for the extraction of valuable components from renewable vegetal sources are highlighted and the potential of this technique for industrial applications is discussed. © 2014 Society of Chemical Industry
Organic matter returns to soils must be higher under organic compared to conventional farming
Authors: Leithold Günter , Hülsbergen Kurt‐Jürgen , Brock Christopher 
Published: August 2014

AbstractThe aim of this paper is to discuss the demand of fresh organic matter (FOM) supply to maintain soil organic matter (SOM) levels and productivity of arable soils under organic management. The basic question is whether the different frame conditions in organic vs. conventional farming result in a different and system‐specific FOM demand. If this is the case, it would follow that the farming system has to be considered in the calculation of SOM balances. SOM balances are the most common decision support tools in organic matter management. A conversion to organic farming in practice usually leads to an increase of SOM levels as well as soil microbial activity over time. The system‐specific driver of this effect is the indispensable extension of the share of (perennial) legumes in crop rotations at the expense of non‐legumes such as cereals, row crops, and maize. Extended legume cropping is essential for N supply in crop rotations as the import of N fertilizer in total is limited by organic farming regulations and mineral N fertilizer may not be used at all. Based on this characteristic of organic management, we argue that the demand of FOM supply to soils must be higher than in conventional crop production. The most relevant factors are (1) the non‐existence of mineral N fertilizer as an external N source that supports the maintenance of SOM by decreasing the demand for SOM‐N, (2) benefits of increasing SOM stocks and turnover for soil productivity under organic management, and, (3) increased mass‐losses of FOM and easily degradable SOM compartments due to higher microbial activity in soils. These effects have to be quantified and must be considered in SOM balances in order to avoid misleading assessments and erroneous decisions.
Use of lyophilised and powdered Gentiana lutea root in fresh beef patties stored under different atmospheres
Authors: Azman Nurul A M , Gordon Michael H , Skowyra Monika , Segovia Francisco , Almajano María Pilar 
Published: August 2014

AbstractBACKGROUNDGentiana lutea root is a medicinal herb that contains many active compounds which contribute to physiological effects, and it has recently attracted much attention as a natural source of antioxidants. The aim of this study was to evaluate the effects on the colour, pH, microbial activities, sensory quality and resistance to lipid oxidation (through the thiobarbituric acid method) during storage of beef patties containing different concentrations of G. lutea. Fresh beef patties were formulated with 0–5 g kg−1 of G. lutea and 0 or 0.5 g kg−1 of ascorbic acid and packed in two different atmospheres, Modified Atmosphere 1 (MAP1) and Modified Atmosphere 2 (MAP2), and stored at 4 ± 1 °C for 10 days. MAP1 contained 20:80 (v/v) O2:CO2 and MAP2 contained 80:20 (v/v) O2:CO2.RESULTSG. lutea extracts possessed antioxidant activity measured by the ferric reducing antioxidant power and the oxygen radical absorbance capacity assays. Beef patties containing 2 g kg−1 of lyophilised G. lutea were stable towards lipid oxidation in both atmospheres (P < 0.05). Beef patties containing a combination of 2 g kg−1 G. lutea and 0.5 g kg−1 ascorbic acid showed significantly reduced changes in colour and in lipid oxidation (P < 0.05).CONCLUSIONThe results from this study demonstrate the potential of G. lutea as a food ingredient in the design of healthier meat commodities. © 2014 Society of Chemical Industry
Microextraction by packed sorbent liquid chromatography with time‐of‐flight mass spectrometry of triazines employing a molecularly imprinted polymer†
Authors: Andrade Felipe Nascimento , Santos‐Neto Álvaro José , Lanças Fernando Mauro 
Published: August 2014

Molecularly imprinted polymers for the determination of triazines were synthesized by precipitation using atrazine as template, methacrylic acid as functional monomer, ethylene glycol dimethacrylate as crosslinker, and 2,2′‐azobisisobutrynitrile as initiator. The polymers were characterized by infrared spectroscopy and scanning electron microscopy and packed in a device for microextraction by packed sorbent aiming for the preconcentration/cleanup of herbicides, such as atrazine, simazine, simetryn, ametryn, and terbutryn in corn samples. Liquid chromatography coupled with time‐of‐flight mass spectrometry was used for the separation and determination of the herbicides. The selectivity coefficient of molecularly imprinted polymers was compared with that of nonimprinted polymer for the binary mixtures of atrazine/propanil and atrazine/picloram, and the values obtained were 15.6 and 2.96, respectively. The analytical curve ranged from 10 to 80 μg/kg (r = 0.989) and the limits of detection and quantification in the corn matrices were 3.3 and 10 μg/kg, respectively. Intra‐ and interday precisions were < 14.8% and accuracy was better than 90.9% for all herbicides. Polymer synthesis was successfully applied to the cleanup and preconcentration of triazines from fortified corn samples with 91.1–109.1% of recovery.
Effervescence‐assisted dispersive liquid–liquid microextraction using a solid effervescent agent as a novel dispersion technique for the analysis of fungicides in apple juice
Authors: Jiang Wenqing , Chen Xiaochu , Liu Fengmao , You Xiangwei , Xue Jiaying 
Published: August 2014

A novel effervescence‐assisted dispersive liquid–liquid microextraction method has been developed for the determination of four fungicides in apple juice samples. In this method, a solid effervescent agent is added into samples to assist the dispersion of extraction solvent. The effervescent agent is environmentally friendly and only produces an increase in the ionic strength and a negligible variation in the pH value of the aqueous sample, which does not interfere with the extraction of the analytes. The parameters affecting the extraction efficiency were investigated including the composition of effervescent agent, effervescent agent amount, formulation of effervescent agent, adding mode of effervescent agent, type and volume of extraction solvent, and pH. Under optimized conditions, the method showed a good linearity within the range of 0.05–2 mg/L for pyrimethanil, fludioxonil, and cyprodinil, and 0.1–4 mg/L for kresoxim‐methyl, with the correlation coefficients >0.998. The limits of detection for the method ranged between 0.005 and 0.01 mg/L. The recoveries of the target fungicides in apple juice samples were in the range of 72.4–110.8% with the relative standard deviations ranging from 1.2 to 6.8%.
One‐Step Preparation of Reduction‐Responsive Biodegradable Polymers as Efficient Intracellular Drug Delivery Platforms
Authors: Cai Tongjiang , Chen Yangjun , Wang Yin , Wang Haibo , Liu Xiangsheng , Jin Qiao , Agarwal Seema , Ji Jian 
Published: August 2014

Reduction‐responsive biodegradable polymeric micelles based on functional 2‐methylene‐1,3‐dioxepane (MDO) copolymers are developed and investigated for triggered doxorubicin (DOX) release. The MDO‐based copolymers P(MDO‐co‐PEGMA‐co‐PDSMA) are synthesized via the simple one‐step radical ring‐opening copolymerization of MDO, poly(ethylene glycol) methyl ether methacrylate (PEGMA), and pyridyldisulfide ethylmethacrylate (PDSMA). The copolymers can self‐assemble to form micelles in aqueous solution. DOX, a model anticancer drug, is loaded into the micelles with the drug loading content (DLC) of 11.3%. The micelles can be disassembled under a reductive environment (10 × 10−3m glutathione), which results in a triggered drug release behavior. The glutathione‐mediated intracellular drug release of DOX‐loaded micelles is investigated against A549 cells. Confocal laser scanning microscopy (CLSM) results demonstrated that DOX‐loaded micelles exhibits faster drug release in glutathione monoester (GSH‐OEt)‐pretreated A549 cells, compared with untreated and buthionine sulfoximine (BSO)‐pretreated A549 cells. Based on the facile synthetic strategy, the reduction‐sensitive biodegradable micelles with triggered intracellular drug release are promising for anticancer drug delivery.
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A common cognitive, psychiatric, and dysmorphic phenotype in carriers of NRXN1 deletion
Authors: Viñas‐Jornet Marina , Esteba‐Castillo Susanna , Gabau Elisabeth , Ribas‐Vidal Núria , Baena Neus , San Joan , Ruiz Anna , Coll Maria Dolors , Novell Ramon , Guitart Miriam 
Published: August 2014

AbstractDeletions in the 2p16.3 region that includes the neurexin (NRXN1) gene are associated with intellectual disability and various psychiatric disorders, in particular, autism and schizophrenia. We present three unrelated patients, two adults and one child, in whom we identified an intragenic 2p16.3 deletion within the NRXN1 gene using an oligonucleotide comparative genomic hybridization array. The three patients presented dual diagnosis that consisted of mild intellectual disability and autism and bipolar disorder. Also, they all shared a dysmorphic phenotype characterized by a long face, deep set eyes, and prominent premaxilla. Genetic analysis of family members showed two inherited deletions. A comprehensive neuropsychological examination of the 2p16.3 deletion carriers revealed the same phenotype, characterized by anxiety disorder, borderline intelligence, and dysexecutive syndrome. The cognitive pattern of dysexecutive syndrome with poor working memory and reduced attention switching, mental flexibility, and verbal fluency was the same than those of the adult probands. We suggest that in addition to intellectual disability and psychiatric disease, NRXN1 deletion is a risk factor for a characteristic cognitive and dysmorphic profile. The new cognitive phenotype found in the 2p16.3 deletion carriers suggests that 2p16.3 deletions might have a wide variable expressivity instead of incomplete penetrance.
Investigation into the structural composition of hydroalcoholic solutions as basis for the development of multiple suppression pulse sequences for NMR measurement of alcoholic beverages
Authors: Monakhova Yulia B. , Mushtakova Svetlana P. , Kuballa Thomas , Lachenmeier Dirk W. 
Published: August 2014

An eight‐fold suppression pulse sequence was recently developed to improve sensitivity in 1H NMR measurements of alcoholic beverages [Magn. Res. Chem. 2011 (49): 734–739]. To ensure that only one combined hydroxyl peak from water and ethanol appears in the spectrum, adjustment to a certain range of ethanol concentrations was required.To explain this observation, the structure of water–ethanol solutions was studied. Hydroalcoholic solutions showed extreme behavior at 25% vol, 46% vol, and 83% vol ethanol according to 1H NMR experiments. Near‐infrared spectroscopy confirmed the occurrence of four significant compounds (‘individual’ ethanol and water structures as well as two water–ethanol complexes of defined composition – 1 : 1 and 1 : 3).The successful multiple suppression can be achieved for every kind of alcoholic beverage with different alcoholic strengths, when the final ethanol concentration is adjusted to a range between 25% vol and 46% vol (e.g. using dilution or pure ethanol addition). In this optimum region, an individual ethanol peak was not detected, because the ‘individual’ water structure and the 1 : 1 ethanol–water complex predominate.The nature of molecular association in ethanol–water solutions is essential to elucidate NMR method development for measurement of alcoholic beverages. The presented approach can be used to optimize other NMR suppression protocols for binary water–organic solvent mixtures, where hydrogen bonding plays a dominant role. Copyright © 2014 John Wiley & Sons, Ltd.
Towards a better control of the radical functionalization of poly(lactic acid)
Authors: Domenichelli Ilaria , Coiai Serena , Cicogna Francesca , Pinzino Calogero , Passaglia Elisa 
Published: August 2014

AbstractThe radical functionalization of poly(lactic acid) (PLA) with maleic anhydride (MA) was thoroughly investigated using different chemical approaches with the purpose of controlling both the grafting degree and the structure/architecture of the final products. First, a new methodology was developed able to provide clear evidence of the grafting and to identify the structure of the inserted groups. The method consists in the derivatization reaction of the grafted succinic anhydride with a fluorescent derivative (1‐naphthylmethylamine), which allows the functionalization to be assessed qualitatively and quantitatively and therefore improves understanding of the radical functionalization mechanism. Then, in order to control the incidence of secondary reactions, which affect the radical process in the presence of MA, new chemicals were investigated as functionalizing agents or as functionalizing co‐agents together with MA. Butyl 3‐(2‐furyl)propenoate was used as a functional molecule capable of stabilizing the macroradical intermediate and then controlling the β‐scission reaction. 4‐Benzoyloxy‐2,2,6,6‐tetramethylpiperidine‐1‐oxyl was tested as a radical mediator capable of modulating the insertion of MA through a simple reversible coupling reaction. The results obtained by both approaches suggest the possibility of stabilizing the PLA macroradical intermediates and accordingly keeping the radical process under control. © 2014 Society of Chemical Industry
Integrated static code analysis and runtime verification
Authors: Sözer H. 
Published: August 2014

SummaryStatic code analysis tools automatically generate alerts for potential software faults that can lead to failures. However, these tools usually generate a very large number of alerts, some of which are subject to false positives. Because of limited resources, it is usually hard to inspect all the alerts. As a complementary approach, runtime verification techniques verify dynamic system behavior with respect to a set of specifications. However, these specifications are usually created manually based on system requirements and constraints. In this paper, we introduce a noval approach and a toolchain for integrated static code analysis and runtime verification. Alerts that are generated by static code analysis tools are utilized for automatically generating runtime verification specifications. On the other hand, runtime verification results are used for automatically generating filters for static code analysis tools to eliminate false positives. The approach is illustrated for the static analysis and runtime verification of an open‐source bibliography reference manager software. Copyright © 2014 John Wiley & Sons, Ltd.
Joint sink deployment and association for multi‐sink wireless camera networks
Authors: Hung Michael Chien‐Chun , Lin Kate Ching‐Ju 
Published: August 2014

AbstractIn this paper, we investigate the problem of joint sink deployment and association (JSDA) in multi‐sink wireless camera networks (WCNs). Each camera in a WCN requires a different streaming rate of delivering its stream back to an access point (sink) because of various surveillance requirements, for example, event detection or target tracking. In a WCN where multiple channels are supported, the sinks must be placed in suitable locations (sink deployment) to collect streams from cameras over nonoverlapping channels, and in addition, each camera must associate with the appropriate sink (sink association) so that its demand rate can be optimally satisfied. To achieve this goal, we first formulate the JSDA problem as an optimization model using mixed‐integer linear programming and prove its NP‐completeness. Two approaches, branch‐and‐bound and our heuristics, iterative sink deployment and association (ISDA), are then developed to solve JSDA. We evaluate the performance via simulations with the traces collected by real measurements and show that ISDA can effectively satisfy cameras' demands with a reasonable computational cost. Copyright © 2014 John Wiley & Sons, Ltd.
Self‐similarity and turbulence characteristics of wind turbine wakes via large‐eddy simulation
Authors: Xie Shengbai , Archer Cristina 
Published: August 2014

AbstractMean and turbulent properties of the wake generated by a single wind turbine are studied in this paper with a new large eddy simulation (LES) code, the wind turbine and turbulence simulator (WiTTS hereafter). WiTTS uses a scale‐dependent Lagrangian dynamical model of the sub‐grid shear stress and actuator lines to simulate the effects of the rotating blades. WiTTS is first tested by simulating neutral boundary layers without and with a wind turbine and then used to study the common assumptions of self‐similarity and axisymmetry of the wake under neutral conditions for a variety of wind speeds and turbine properties. We find that the wind velocity deficit generally remains self similarity to a Gaussian distribution in the horizontal. In the vertical, the Gaussian self‐similarity is still valid in the upper part of the wake, but it breaks down in the region of the wake close to the ground. The horizontal expansion of the wake is always faster and greater than the vertical expansion under neutral stability due to wind shear and impact with the ground. Two modifications to existing equations for the mean velocity deficit and the maximum added turbulence intensity are proposed and successfully tested. The anisotropic wake expansion is taken into account in the modified model of the mean velocity deficit. Turbulent kinetic energy (TKE) budgets show that production and advection exceed dissipation and turbulent transport. The nacelle causes significant increase of every term in the TKE budget in the near wake. In conclusion, WiTTS performs satisfactorily in the rotor region of wind turbine wakes under neutral stability. Copyright © 2014 John Wiley & Sons, Ltd.
Effect of Cooked White Rice with High β-glucan Barley on Appetite and Energy Intake in Healthy Japanese Subjects: A Randomized Controlled Trial
Authors: Aoe Seiichiro , Ikenaga Takeshi , Noguchi Hiroki , Kohashi Chieko , Kakumoto Keiji , Kohda Noriyuki 
Published: August 2014

Abstract
White rice is a dominant grain-based food in Japan, but excess intake of polished rice may cause obesity. Barley is a grain-based food, similar to white rice, but it has the potential to control appetite and reduce energy intake. We investigated the effect of cooked white rice with high β-glucan barley on appetite and energy intake. The study was conducted as a randomized crossover design with twenty-one healthy Japanese women [mean ± standard deviation body mass index (BMI) 23.3 ± 0.7 kg/m2]. Subjects consumed a breakfast of cooked white rice with high β-glucan barley (BAR) or white rice (WR), followed by an ad libitum lunch and dinner. Energy intake was measured at the lunch and the dinner using plate waste. Subjects’ perception scores on hunger, fullness, satiety, and prospective food consumption were assessed using a visual analogue scale (VAS) before and after the breakfast, lunch and dinner. BAR significantly reduced the VAS scores of hunger and prospective food consumption, and increased fullness before lunch compared to WR (P = 0.032, 0.019 and 0.038, respectively). Energy intake at lunch and the cumulative energy intake (lunch + dinner) subsequent to BAR consumption were significantly lower than WR (P = 0.035 and 0.021, respectively). BAR was able to modulate appetite and reduce energy intake. The combination of white rice with high β-glucan barley could play a beneficial role in preventing and treating obesity and other obesity-related metabolic diseases.
Photosulfochlorination Synthesis and Physicochemical Properties of Methyl Ester Sulfonates Derived from Lauric and Myristic Acids
Authors: Asselah Amel , Tazerouti Amel 
Published: August 2014

AbstractThe photosulfochlorination process has been used in earlier works to produce n‐alkane sulfonates. In this work, this process was applied for the first time on lauric and myristic fatty acids, leading to methyl ester sulfonates (MESs). The operating conditions were optimized and the isolation method described. Apart from the known advantages of this reaction, namely the use of sulfuryl chloride, the visible light and short reaction time, this process led to a clear mono‐sulfonate products and thus allowed avoiding the bleaching step. The chemical composition of these surfactants was determined and their structures characterized by Fourier transform infrared spectroscopy, liquid chromatography‐electrospray ionization tandem mass spectrometry and proton nuclear magnetic resonance. The physicochemical properties of these surfactants such as surface tension, critical micelle concentration, maximum surface excess and minimum area per molecule of surfactant at the air/water interface were determined. The Krafft point was determined experimentally and compared to the MES literature data. The experimental and calculated hydrophilic–lipophilic balance values obtained compared well. The foaming power using Bartsch's method was presented and the results obtained compared to those of similar structures and those of sodium dodecyl sulfate.
Analysis of C18:1cis and trans fatty acid isomers by the combination of gas‐liquid chromatography of 4,4‐dimethyloxazoline derivatives and methyl esters
Authors: Aro Antti , Kosmeijer‐Schuil Truus , van de Bovenkamp Peter , Hulshof Paul , Zock Peter , Katan Martijn B. 
Published: August 2014

AbstractTrans fatty acids in foods are usually analyzed by gas‐liquid chromatography (GLC) of fatty acid methyl esters (FAME). However, this method may produce erroneously low values because of insufficient separation between cis and trans isomers. Separation can be optimized by preceding silver‐ion thin‐layer chromatography (Ag‐TLC), but this is laborious. We have developed an efficient method for the separation of 18‐carbon trans fatty acid isomers by combining GLC of FAME with GLC of fatty acid 4,4‐dimethyloxazoline (DMOX) derivatives. We validated this method against conventional GLC of FAME, with and without preceding Ag‐TLC. Fatty acid isomers were identified by comparison with standards, based on retention times and mass spectrometry. Analysis of DMOX derivatives allowed the 13t, 14t, and 15t isomers to be separated from the cis isomers. The combination of the GLC analyses of FAME and DMOX derivatives gave results comparable with those obtained by GLC of FAME after preceding Ag‐TLC, while saving about 100 h of manpower per 25 samples. It allowed the identification and quantitation of 11 trans and 8 cis isomers and resulted in 25% higher values for total C18:1trans, compared with the analysis of FAME alone. The combination of DMOX and FAME analyses, as applied to the analysis of 14 foods that contained ruminant fat and partially hydrogenated vegetable and fish oils, indicated that the most common isomers were 11t in ruminant fats, 9t in partially hydrogenated fish fats, and either 9t or 10t in partially hydrogenated vegetable fats. The combination of GLC analyses of FAME and DMOX derivatives of fatty acids improves the quantitation of 18‐carbon fatty acid isomers and may replace the laborious and time‐consuming Ag‐TLC.