bluuebunny/crossref_metadata_2025_split huggingface dataset:
Facies Analysis and Depositional Environment of the Jurassic, Jumara Dome Sediments, Kachchh, Western India
Authors: Ahmad A. H. M. , Khan A. F. , Wasim S. M. 
Published: August 2013

Abstract
The study deals with the depositional environment of Jumara Dome sediments. The Jumara Dome is an important outcrop of Bathonian to Oxfordian sediments amongst the Kachchh Mainland exposures. On the basis of facies analysis three associations have been documented, namely, G-1 consisting of low energy facies comprising of cross-bedded sandstone, massive sandstone, grey shale and thin bedded sandstone, bioclastic - lithoclastic grainstone, bioclastic - lithoclastic packstone, microbioclastic packstone/ wackestone, bioturbated laminated wackestone to mudstone and pelagic lime mudstone; G-II consisting of moderate energy facies comprising of laminated sandstone and grapestone or agglutinated grainstone; G-III consisting of high energy facies comprising of interbedded gypsiferous shale and sandstone/ siltstone, oolitic grainstone to conglomerate and bioclastic grainstone. The facies associations reflect an ideal shallowing upward sequence representing slope, bioclast bar, lagoon and inner shelf. Presence of wide range of facies indicates that the rocks of the studied area were deposited during the fluctuating sea level, interrupted by the storms, in the shallow marine environment.
Features of the Japanese national dementia strategy in comparison with international dementia policies: How should a national dementia policy interact with the public health‐ and social‐care systems?
Authors: Nakanishi Miharu , Nakashima Taeko 
Published: August 2013

AbstractBackgroundThe Ministry of Health, Labour, and Welfare of the Japanese national government announced a “Five‐Year Plan for Promotion of Measures Against Dementia (Orange Plan)” in September 2012. This article described features of the Japanese dementia strategy in comparison with international dementia policies.MethodsAn international comparative study was implemented on national dementia policies to seek suggestions for Japanese national strategy. The study consisted of a bibliographical survey, a field survey, and an online case vignette survey in several countries.ResultsThe Japanese health‐ and social‐care system had multiple access points in the dementia care pathway, as did Australia, France, South Korea, and the Netherlands. Contrary to Japan, a simplified access point was observed in Denmark, England, and Sweden. The Orange Plan aimed to establish specific health‐care services, social‐care services, and the coordination of agencies for persons with dementia. However, fragmentation remains in the dementia care pathway.ConclusionThe national government should examine fundamental revisions in health, social‐care services, and advocacy in joint initiatives with Alzheimer's Association Japan to improve the national dementia strategy.
Transition delay in a boundary layer flow using active control
Authors: Semeraro Onofrio , Bagheri Shervin , Brandt Luca , Henningson Dan S. 
Published: August 2013

AbstractActive linear control is applied to delay the onset of laminar–turbulent transition in the boundary layer over a flat plate. The analysis is carried out by numerical simulations of the nonlinear, transitional regime. A three-dimensional, localized initial condition triggering Tollmien–Schlichting waves of finite amplitude is used to numerically simulate the transition to turbulence. Linear quadratic Gaussian controllers based on reduced-order models of the linearized Navier–Stokes equations are designed, where the wall sensors and the actuators are localized in space. A parametric analysis is carried out in the nonlinear regime, for different disturbance amplitudes, by investigating the effects of the actuation on the flow due to different distributions of the localized actuators along the spanwise direction, different sizes of the actuators and the effort of the controllers. We identify the range of parameters where the controllers are effective and highlight the limits of the device for high amplitudes and strong control action. Despite the fully linear control approach, it is shown that the device is effective in delaying the onset of laminar–turbulent transition in the presence of packets characterized by amplitudes $a\approx 1\hspace{0.167em} \% $ of the free stream velocity at the actuator location. Up to these amplitudes, it is found that a proper choice of the actuators positively affects the performance of the controller. For a transitional case, $a\approx 0. 20\hspace{0.167em} \% $, we show a transition delay of $\Delta {\mathit{Re}}_{x} = 3. 0\times 1{0}^{5} $.
Low-dimensional models for compressible temporally developing shear layers
Authors: Qawasmeh Bashar R. , Wei Mingjun 
Published: August 2013

AbstractA methodology to achieve extremely-low-dimensional models for temporally developing shear layers is extended from incompressible flows to weakly compressible flows. The key idea is to first remove the slow variation (i.e. viscous growth of shear layers) through symmetry reduction, so that the model reduction using proper orthogonal decomposition (POD)-Galerkin projection in the symmetry-reduced space becomes more efficient. However, for the approach to work for compressible flows, thermodynamic variables need to be retained. We choose the isentropic Navier–Stokes equations for the simplicity and the availability of a well-defined inner product for total energy. To capture basic dynamics, the compressible low-dimensional model requires only two POD modes for each frequency. Thus, a two-mode model is capable of representing single-frequency dynamics such as vortex roll-up, and a four-mode model is capable of representing the nonlinear dynamics involving a fundamental frequency and its subharmonic, such as vortex pairing and merging. The compressible model shows similar behaviour and accuracy as the incompressible model. However, because of the consistency of the inner product defined for POD and for projection in the current compressible model, the orthogonality is kept and it results in simple formulation. More importantly, the inclusion of compressibility opens an entirely new avenue for the discussion of compressibility effect and possible description of aeroacoustics and thermodynamics. Finally, the model is extended to different flow parameters without additional numerical simulation. The extension of the compressible four-mode model includes different Mach numbers and Reynolds numbers. We can clearly observe the change in the nonlinear interaction of modes at two frequencies and the associated promotion or delay of vortex pairing by varying compressibility and viscosity. The dynamic response of the low-dimensional model to different flow parameters is consistent with the vortex dynamics observed in experiments and numerical simulation.
The effect of small viscosity and diffusivity on the marginal stability of stably stratified shear flows
Authors: Thorpe S. A. , Smyth W. D. , Li Lin 
Published: August 2013

AbstractThe effect of non-zero, but small, viscosity and diffusivity on the marginal stability of a stably stratified shear flow is examined by making perturbations around the neutral solution for an inviscid and non-diffusive flow. The results apply to turbulent flows in which horizontal and vertical turbulent transports of momentum and buoyancy are represented by eddy coefficients of viscosity and diffusivity that vary in the vertical ($z$) direction. General expressions are derived for the modified phase speed and the growth rate of small disturbances as a function of wavenumber. To first order in their coefficients, the effect on the phase speed of adding viscosity and diffusivity is zero. Growth rates are found for two mean flows when the horizontal or vertical coefficients of viscosity and diffusivity vary in $z$ in such a way that the rates can be found analytically. The first flow, denoted as a ‘Holmboe flow’, has a velocity and density interface: the mean horizontal velocity and the density are both proportional to $\tanh az$, where $a$ is proportional to the inverse of the interface thickness. The second, ‘Drazin flow’, has a similar velocity variation in $z$ but uniform density gradient. The analytical results compare favourably with numerical calculations. Small horizontal coefficients of viscosity and diffusivity may affect disturbances to the flow in opposite ways. Although the effect of uniform vertical coefficients of viscosity is to decrease the growth rates, and uniform vertical coefficients of diffusivity increase them, cases are found in which, with suitably chosen $z$ dependence, vertical coefficients of viscosity (or diffusivity) may cause a previously neutral disturbance to grow (or to diminish); viscosity may destabilize a stably stratified shear flow. The introduction of viscosity and diffusivity may consequently increase the critical Richardson number to a value exceeding $1/ 4$. While some patterns of behaviour are apparent, no simple rule appears to hold about whether flows that are neutral in the absence of these effects (viscosity or diffusivity) will be stabilized or destabilized when they are added. One such rule, namely our conjecture that viscosity is always stabilizing and that diffusivity is destabilizing, is explicitly refuted.
Trans-tensor tympani facial nerve decompression in traumatic facial nerve palsy
Authors: Jung J H , Hyun S M , Park H J , Yoon T H 
Published: August 2013

AbstractObjective:The surgical approaches previously reported for facial nerve decompression have focussed on achieving good exposure of the lateral or superior aspects of the geniculate ganglion. This report aims to describe a unique case of facial nerve decompression beneath the geniculate ganglion.Patient:A 30-year-old woman with right-sided facial palsy due to a temporal bone fracture.Intervention:Bony fragments at the base of the geniculate ganglion were removed via a trans-tensor tympani approach with extended posterior tympanotomy.Results:The patient's facial movement recovered successfully, without complications such as sensorineural hearing loss and conductive hearing loss.Conclusion:In rare cases requiring decompression of the facial nerve inferior to the perigeniculate area, the trans-tensor tympani approach should be considered as a valuable alternative option when surgical intervention is considered.
Control ofTaenia soliumtaeniasis/cysticercosis: past practices and new possibilities
Authors: LIGHTOWLERS MARSHALL W. 
Published: August 2013

SUMMARYNeurocysticercosis continues to be a major health burden on humans living in many regions of the world, despite the availability of highly effective taeniacides and identification of the cause,Taenia solium, as being potentially eradicable. SeveralT. soliumcontrol trials have been undertaken, generally achieving limited success and none that has been fully documented has achieved what was demonstrated to be a sustainable level of disease control. Pigs act as intermediate hosts forT. soliumand two new control tools have become available for application in pigs – single-dose oxfendazole treatment of porcine cysticercosis and the TSOL18 vaccine. Three potential intervention scenarios for pigs are compared for control of cysticercosis, using either oxfendazole or vaccination. A control scenario involving vaccination plus oxfendazole treatment delivered at 4 monthly intervals was predicted to achieve the best outcome, with no pigs slaughtered at 12 months of age having viableT. soliumcysticerci. Now that new control tools are available, there are opportunities to concentrate research attention on evaluation of novel control scenarios leading to the implementation of effective and sustainable control programmes and a reduction in the global burden of neurocysticercosis.
Off-pump snare technique for congenital left atrial appendage aneurysm
Authors: DiBardino Daniel J. , Aggarwal Avichal , Knudson Jarrod D. 
Published: August 2013

AbstractLeft atrial appendage aneurysm is an extremely rare anomaly and as such has been rarely imaged or seen intraoperatively with very little accumulated management experience. The available scant published literature stresses resection on cardiopulmonary bypass as the safest and by far the most commonly applied technique. We suggest a novel alternative imaging-guided management utilising an off-pump tourniquet snare technique under live transoesophageal echocardiography.
Hippocampal Volume and Memory and Learning Outcomes at 7 Years in Children Born Very Preterm
Authors: Omizzolo Cristina , Thompson Deanne K. , Scratch Shannon E. , Stargatt Robyn , Lee Katherine J. , Cheong Jeanie , Roberts Gehan , Doyle Lex W. , Anderson Peter J. 
Published: August 2013

AbstractUsing magnetic resonance imaging, this study compared hippocampal volume between 145 very preterm children and 34 children born full-term at 7 years of age. The relationship between hippocampal volume and memory and learning impairments at 7 years was also investigated. Manual hippocampal segmentation and subsequent three-dimensional volumetric analysis revealed reduced hippocampal volumes in very preterm children compared with term peers. However, this relationship did not remain after correcting for whole brain volume and neonatal brain abnormality. Contrary to expectations, hippocampal volume in the very preterm cohort was not related to memory and learning outcomes. Further research investigating the effects of very preterm birth on more extensive networks in the brain that support memory and learning in middle childhood is needed. (JINS, 2013, 19, 1–11)
Exploring attitudes and opinions of radiation therapists in British Columbia towards advanced practice
Authors: Kinamore Cher 
Published: August 2013

AbstractIntroductionAlthough the notion of advanced practice (AP) has been widely accepted and implemented in some countries, for example, the United Kingdom, in Canada it is has yet to be widely tested as a model of working. Currently it has been implemented and evaluated in Ontario, but this approach is not widespread across the country. To date in British Columbia (BC), there are no advanced practitioners and no research has been conducted regarding the opinions and attitudes of radiation therapists (RTs) in BC towards the implementation of AP. Understanding RTs attitudes and perceptions towards AP may be important when considering the acceptance and implementation of new roles. The research objectives were to explore the attitudes and opinions of RTs and establish what the term AP means to BC RTs, and also to discover what they consider to be benefits, and barriers to implementing AP.Materials and methodsA quantitative approach was utilised and an on-line questionnaire was sent to 266 RTs that currently practice in BC. Likert and demographic questions were used to explore the definition of AP and ascertain opinions about the barriers and benefits of implementing AP in BC.ResultsA total of 183 questionnaires were completed for a response rate of 69%. The majority of respondents agreed with the Canadian Association of Medical Radiation Technologies (CAMRT) and the literature's definition of AP. Cost, time, lack of support and training and issues of medical dominance were cited as barriers. Job satisfaction, autonomy, and increased recruitment and retention of staff were considered benefits.ConclusionsAlthough RTs believe there are obstacles to be overcome regarding the adoption and implementation of AP, these are outweighed by the potential benefits such as enhanced patient care due to increased levels of professional knowledge and development that can lead to increased levels of job satisfaction. These are seen as important drivers for creating the AP role in BC.
A qualitative analysis of radiation therapy students’ professional placement journals
Authors: Findlay Naomi , Dempsey Shane E. , Warren-Forward Helen M. 
Published: August 2013

AbstractPurposeStudent experience on clinical placement is not well captured with traditional program evaluation tools. This study aims to complete a qualitative analysis of the reflective clinical journals completed during professional placement by radiation therapy (RT) students in order to uncover the issues that affect students on placement and how these change as the student's progress through the program.Materials and methodsA qualitative descriptive analysis (QDA) was undertaken on the descriptive content of student journals completed by 97 students over 3 consecutive years while undertaking professional placement in Radiation Oncology Treatment Centres within Australia. Two coders used a QDA sourcebook specifically designed for the research to independently analyse the descriptive content of the reflective journals for four main categories and 18 subcategories.ResultsThe result revealed a statistically significant increased tendency to discuss clinical environment and a decreased tendency to discuss the patient, 92·9–12·5% (coder 1) and 85·7–18·8% (coder 2), as they progressed through the program.ConclusionsThe results of this study showed some similarities with studies completed in other health professions; however, the breadth of issues explored within the content of these RT student journals demonstrates the true diversity of the RT student experience on professional placement.
A multi-engine approach to answer-set programming
Authors: MARATEA MARCO , PULINA LUCA , RICCA FRANCESCO 
Published: August 2013

AbstractAnswer-set programming (ASP) is a truly declarative programming paradigm proposed in the area of non-monotonic reasoning and logic programming, which has been recently employed in many applications. The development of efficient ASP systems is, thus, crucial. Having in mind the task of improving the solving methods for ASP, there are two usual ways to reach this goal: (i) extending state-of-the-art techniques and ASP solvers or (ii) designing a new ASP solver from scratch. An alternative to these trends is to build on top of state-of-the-art solvers, and to apply machine learning techniques for choosing automatically the “best” available solver on a per-instance basis.In this paper, we pursue this latter direction. We first define a set of cheap-to-compute syntactic features that characterize several aspects of ASP programs. Then, we apply classification methods that, given the features of the instances in atrainingset and the solvers' performance on these instances, inductively learn algorithm selection strategies to be applied to atestset. We report the results of a number of experiments considering solvers and different training and test sets of instances taken from the ones submitted to the “System Track” of the Third ASP Competition. Our analysis shows that by applying machine learning techniques to ASP solving, it is possible to obtain very robust performance: our approach can solve more instances compared with any solver that entered the Third ASP Competition.
Knockdown of specific host factors protects against influenza virus-induced cell death
Authors: Tran A T , Rahim M N , Ranadheera C , Kroeker A , Cortens J P , Opanubi K J , Wilkins J A , Coombs K M 
Published: August 2013

AbstractCell death is a characteristic consequence of cellular infection by influenza virus. Mounting evidence indicates the critical involvement of host-mediated cellular death pathways in promoting efficient influenza virus replication. Furthermore, it appears that many signaling pathways, such as NF-κB, formerly suspected to solely promote cell survival, can also be manipulated to induce cell death. Current understanding of the cell death pathways involved in influenza virus-mediated cytopathology and in virus replication is limited. This study was designed to identify host genes that are required for influenza-induced cell death. The approach was to perform genome-wide lentiviral-mediated human gene silencing in A549 cells and determine which genes could be silenced to provide resistance to influenza-induced cell death. The assay proved to be highly reproducible with 138 genes being identified in independent screens. The results were independently validated using siRNA to each of these candidates. Graded protection was observed in this screen with the silencing of any of 19 genes, each providing >85% protection. Three gene products, TNFSF13 (APRIL), TNFSF12-TNFSF13 (TWE-PRIL) and USP47, were selected because of the high levels of protection conferred by their silencing. Protein and mRNA silencing and protection from influenza-induced cell death was confirmed using multiple shRNA clones and siRNA, indicating the specificity of the effects. USP47 knockdown prevented proper viral entry into the host cell, whereas TNFSF12-13/TNFSF13 knockdown blocked a late stage in viral replication. This screening approach offers the means to identify a large number of potential candidates for the analysis of viral-induced cell death. These results may also have much broader applicability in defining regulatory mechanisms involved in cell survival.
Metaproteomics of cellulose methanisation under thermophilic conditions reveals a surprisingly high proteolytic activity
Authors: Lü Fan , Bize Ariane , Guillot Alain , Monnet Véronique , Madigou Céline , Chapleur Olivier , Mazéas Laurent , He Pinjing , Bouchez Théodore 
Published: August 2013

Abstract
Cellulose is the most abundant biopolymer on Earth. Optimising energy recovery from this renewable but recalcitrant material is a key issue. The metaproteome expressed by thermophilic communities during cellulose anaerobic digestion was investigated in microcosms. By multiplying the analytical replicates (65 protein fractions analysed by MS/MS) and relying solely on public protein databases, more than 500 non-redundant protein functions were identified. The taxonomic community structure as inferred from the metaproteomic data set was in good overall agreement with 16S rRNA gene tag pyrosequencing and fluorescent in situ hybridisation analyses. Numerous functions related to cellulose and hemicellulose hydrolysis and fermentation catalysed by bacteria related to Caldicellulosiruptor spp. and Clostridium thermocellum were retrieved, indicating their key role in the cellulose-degradation process and also suggesting their complementary action. Despite the abundance of acetate as a major fermentation product, key methanogenesis enzymes from the acetoclastic pathway were not detected. In contrast, enzymes from the hydrogenotrophic pathway affiliated to Methanothermobacter were almost exclusively identified for methanogenesis, suggesting a syntrophic acetate oxidation process coupled to hydrogenotrophic methanogenesis. Isotopic analyses confirmed the high dominance of the hydrogenotrophic methanogenesis. Very surprising was the identification of an abundant proteolytic activity from Coprothermobacter proteolyticus strains, probably acting as scavenger and/or predator performing proteolysis and fermentation. Metaproteomics thus appeared as an efficient tool to unravel and characterise metabolic networks as well as ecological interactions during methanisation bioprocesses. More generally, metaproteomics provides direct functional insights at a limited cost, and its attractiveness should increase in the future as sequence databases are growing exponentially.