bluuebunny/crossref_metadata_2025_split huggingface dataset:
Complexation of Surfactant/β‐Cyclodextrin to Inhibit Surfactant Adsorption onto Sand, Kaolin, and Shale for Applications in Enhanced Oil Recovery Processes. Part I: Static Adsorption Analysis
Authors: Kittisrisawai Sirinthip , Romero‐Zerón Laura Beatriz 
Published: May 2015

AbstractSurfactant adsorption onto solid surfaces is a major issue during surfactant flooding in enhanced oil recovery applications; it decreases the effectiveness of the chemical injection making the process uneconomical. Therefore, it was hypothesized that the adsorption of surfactant onto solid surfaces could be inhibited using a surfactant delivery system based on the complexation between the hydrophobic tail of anionic surfactants and β‐cyclodextrin (β‐CD). Proton nuclear magnetic resonance spectroscopy was used to confirm the complexation of sodium dodecyl sulfate (SDS)/β‐CD. Surface tension analysis was used to establish the stoichiometry of the complexation and the binding constant (Ka). Static adsorption testing was applied to determine the adsorption of surfactant onto different solids (sandstone, shale, and kaolinite). The release of the surfactant from the β‐CD cavity was qualitatively evaluated through bottle testing. The formation of the inclusion complex SDS/β‐CD with a 1:1 stoichiometry was confirmed. The Ka of the complexations increases as salinity and hardness concentration increases. The encapsulation of the surfactant into the β‐CD cavity decreases the adsorption of surfactant onto solid surfaces up to 79 %. Qualitative observations indicate that in the presence of solid adsorbents partially saturated with crude oil, the β‐CD cavity releases surfactant molecules, which migrate towards the oil–water interface.
Glyceroglycolipids Affect Uptake of Carotenoids Solubilized in Mixed Micelles by Human Intestinal Caco‐2 Cells
Authors: Kotake‐Nara Eiichi , Yonekura Lina , Nagao Akihiko 
Published: May 2015

AbstractWe previously reported that phospholipids markedly affected the uptake of carotenoids solubilized in mixed micelles by human intestinal Caco‐2 cells. In the present study, we found that two classes of dietary glyceroglycolipids and the corresponding lysoglyceroglycolipids affected uptake of β‐carotene and lutein by differentiated Caco‐2 cells. The levels of carotenoid uptake from micelles containing digalactosyldiacylglycerol or sulfoquinovosyldiacylglycerol were significantly lower than that from control micelles. On the other hand, the uptakes from micelles containing digalactosylmonoacylglycerol or sulfoquinovosylmonoacylglycerol were significantly higher than that from control micelles. In dispersed cells and Caco‐2 cells with poor cell‐to‐cell adhesion, however, the levels of uptake from micelles containing these lyso‐lipids were much lower than that from control micelles. The uptake levels from control micelles were markedly decreased depending on the development of cell‐to‐cell/cell–matrix adhesion in Caco‐2 cells, but the uptake levels from the micelles containing these lyso‐lipids were not substantially changed, suggesting that the intercellular barrier formed by cell‐to‐cell/cell–matrix adhesion inhibited the uptake from control micelles, but not from the lyso‐lipid‐containing micelles. The lyso‐lipids appeared to enhance carotenoid uptake by decreasing the intercellular barrier integrity. The results showed that some types of glyceroglycolipids have the potential to modify the intestinal uptake of carotenoids.
Piezo1 ion channel pore properties are dictated by C-terminal region
Authors: Coste Bertrand , Murthy Swetha E. , Mathur Jayanti , Schmidt Manuela , Mechioukhi Yasmine , Delmas Patrick , Patapoutian Ardem 
Published: May 2015

AbstractPiezo1 and Piezo2 encode mechanically activated cation channels that function as mechanotransducers involved in vascular system development and touch sensing, respectively. Structural features of Piezos remain unknown. Mouse Piezo1 is bioinformatically predicted to have 30–40 transmembrane (TM) domains. Here, we find that nine of the putative inter-transmembrane regions are accessible from the extracellular side. We use chimeras between mPiezo1 and dPiezo to show that ion-permeation properties are conferred by C-terminal region. We further identify a glutamate residue within a conserved region adjacent to the last two putative TM domains of the protein, that when mutated, affects unitary conductance and ion selectivity, and modulates pore block. We propose that this amino acid is either in the pore or closely associates with the pore. Our results describe important structural motifs of this channel family and lay the groundwork for a mechanistic understanding of how Piezos are mechanically gated and conduct ions.
An archive of longitudinal recordings of the vocalizations of adult Gombe chimpanzees
Authors: Plooij Frans X. , van de Rijt-Plooij Hetty , Fischer Martha , Wilson Michael L. , Pusey Anne 
Published: May 2015

AbstractStudies of chimpanzee vocal communication provide valuable insights into the evolution of communication in complex societies, and also comparative data for understanding the evolution of human language. One particularly valuable dataset of recordings from free-living chimpanzees was collected by Frans X. Plooij and the late Hetty van de Rijt-Plooij at Gombe National Park, Tanzania (1971–73). These audio specimens, which have not yet been analysed, total over 10 h on 28 tapes, including 7 tapes focusing on adult individuals with a total of 605 recordings. In 2014 the first part of that collection of audio specimens covering the vocalizations of the immature Gombe chimpanzees was made available. The data package described here covers the vocalizations of the adult chimpanzees. We expect these recordings will prove useful for studies on topics including referential signalling and the emergence of dialects. The digitized sound recordings were stored in the Macaulay Library and the Dryad Repository. In addition, the original notes on the contexts of the calls were translated and transcribed from Dutch into English.
A novel highly differentially expressed gene in wheat endosperm associated with bread quality
Authors: Furtado A. , Bundock P. C. , Banks P. M. , Fox G. , Yin X. , Henry R. J. 
Published: May 2015

AbstractAnalysis of gene expression in developing wheat seeds was used to identify a gene, wheat bread making (wbm), with highly differential expression (~1000 fold) in the starchy endosperm of genotypes varying in bread making quality. Several alleles differing in the 5’-upstream region (promoter) of this gene were identified, with one present only in genotypes with high levels of wbm expression. RNA-Seq analysis revealed low or no wbm expression in most genotypes but high expression (0.2-0.4% of total gene expression) in genotypes that had good bread loaf volume. The wbm gene is predicted to encode a mature protein of 48 amino acids (including four cysteine residues) not previously identified in association with wheat quality, possibly because of its small size and low frequency in the wheat gene pool. Genotypes with high wbm expression all had good bread making quality but not always good physical dough qualities. The predicted protein was sulphur rich suggesting the possibility of a contribution to bread loaf volume by supporting the crossing linking of proteins in gluten. Improved understanding of the molecular basis of differences in bread making quality may allow more rapid development of high performing genotypes with acceptable end-use properties and facilitate increased wheat production.
E3 SUMO ligase AtSIZ1 positively regulates SLY1-mediated GA signalling and plant development
Authors: Kim Sung-Il , Park Bong Soo , Kim Do Youn , Yeu Song Yion , Song Sang Ik , Song Jong Tae , Seo Hak Soo 
Published: May 2015

Gibberellins affect various plant development processes including germination, cell division and elongation, and flowering. A large number of studies have been carried out to address the molecular mechanisms that mediate gibberellin signalling effects on plant growth. However, such studies have been limited to DELLA protein degradation; the regulatory mechanisms controlling how the stability and function of SLEEPY1 (SLY1), a protein that interacts with target DELLA proteins as components of the Skp, Cullin, F-box (SCF)SLY1 complex, are modulated at the post-translational level have not been addressed. In the present study, we show that the E3 SUMO (small ubiquitin-related modifier) ligase AtSIZ1 regulates gibberellic acid signalling in Arabidopsis species by sumoylating SLY1. SLY1 was less abundant in siz1–2 mutants than in wild-type plants, but the DELLA protein repressor of ga1–3 (RGA) was more abundant in siz1–2 mutants than in wild-type plants. SLY1 also accumulated to a high level in the SUMO protease mutant esd4. Transgenic sly1–13 mutants over-expressing SLY1 were phenotypically similar to wild-type plants; however, sly1–13 plants over-expressing a mutated mSLY1 protein (K122R, a mutation at the sumoylation site) retained the mutant dwarfing phenotype. Over-expression of SLY1 in sly1–13 mutants resulted in a return of RGA levels to wild-type levels, but RGA accumulated to high levels in mutants over-expressing mSLY1. RGA was clearly detected in Arabidopsis co-expressing AtSIZ1 and mSLY1, but not in plants co-expressing AtSIZ1 and SLY1. In addition, sumoylated SLY1 interacted with RGA and SLY1 sumoylation was significantly increased by GA. Taken together, our results indicate that, in Arabidopsis, AtSIZ1 positively controls GA signalling through SLY1 sumoylation.
Designer small molecules to target calcium signalling
Authors: Swarbrick Joanna M. , Riley Andrew M. , Mills Stephen J. , Potter Barry V.L. 
Published: May 2015

Synthetic compounds open up new avenues to interrogate and manipulate intracellular Ca2+ signalling pathways. They may ultimately lead to drug-like analogues to intervene in disease. Recent advances in chemical biology tools available to probe Ca2+ signalling are described, with a particular focus on those synthetic analogues from our group that have enhanced biological understanding or represent a step towards more drug-like molecules. Adenophostin (AdA) is the most potent known agonist at the inositol 1,4,5-trisphosphate receptor (IP3R) and synthetic analogues provide a binding model for receptor activation and channel opening. 2-O-Modified inositol 1,4,5-trisphosphate (IP3) derivatives that are partial agonists at the IP3R reveal key conformational changes of the receptor upon ligand binding. Biphenyl polyphosphates illustrate that simple non-inositol surrogates can be engineered to give prototype IP3R agonists or antagonists and act as templates for protein co-crystallization. Cyclic adenosine 5′-diphosphoribose (cADPR) can be selectively modified using total synthesis, generating chemically and biologically stable tools to investigate Ca2+ release via the ryanodine receptor (RyR) and to interfere with cADPR synthesis and degradation. The first neutral analogues with a synthetic pyrophosphate bioisostere surprisingly retain the ability to release Ca2+, suggesting a new route to membrane-permeant tools. Adenosine 5′-diphosphoribose (ADPR) activates the Ca2+-, Na+- and K+-permeable transient receptor potential melastatin 2 (TRPM2) cation channel. Synthetic ADPR analogues provide the first structure-activity relationship (SAR) for this emerging messenger and the first functional antagonists. An analogue based on the nicotinic acid motif of nicotinic acid adenine dinucleotide phosphate (NAADP) antagonizes NAADP-mediated Ca2+ release in vitro and is effective in vivo against induced heart arrhythmia and autoimmune disease, illustrating the therapeutic potential of targeted small molecules.
The ryanodine receptor provides high throughput Ca2+-release but is precisely regulated by networks of associated proteins: a focus on proteins relevant to phosphorylation
Authors: O'Brien Fiona , Venturi Elisa , Sitsapesan Rebecca 
Published: May 2015

Once opened, ryanodine receptors (RyR) are efficient pathways for the release of Ca2+ from the endoplasmic/sarcoplasmic reticulum (ER/SR). The precise nature of the Ca2+-release event, however, requires fine-tuning for the specific process and type of cell involved. For example, the spatial organization of RyRs, the luminal [Ca2+] and the influence of soluble regulators that fluctuate under physiological and pathophysiological control mechanisms, all affect the amplitude and duration of RyR Ca2+ fluxes. Various proteins are docked tightly to the huge bulky structure of RyR and there is growing evidence that, together, they provide a sophisticated and integrated system for regulating RyR channel gating. This review focuses on those proteins that are relevant to phosphorylation of RyR channels with particular reference to the cardiac isoform of RyR (RyR2). How phosphorylation of RyR affects channel activity and whether proteins such as the FK-506 binding proteins (FKBP12 and FKBP12.6) are involved, have been highly controversial subjects for more than a decade. But that is expected given the large number of participating proteins, the relevance of phosphorylation in heart failure and inherited arrhythmic diseases, and the frustrations of predicting relationships between structure and function before the advent of a high resolution structure of RyR.
Regulation of TRPML1 function
Authors: Waller-Evans Helen , Lloyd-Evans Emyr 
Published: May 2015

TRPML1 is a ubiquitously expressed cation channel found on lysosomes and late endosomes. Mutations in TRPML1 cause mucolipidosis type IV and it has been implicated in Alzheimer's disease and HIV. However, the mechanisms by which TRPML1 activity is regulated are not well understood. This review summarizes the current understanding of TRPML1 activation and regulation.
Northern Ascriptions in MS Lansdowne 1033
Authors: Ruano-García Javier 
Published: May 2015

SummaryThis paper examines the contribution of theDictionariolum Islandicumto White Kennett’s (1660–1728) unpublishedEtymological Collections of English Words and Provincial Expressions(BL MS Lansdowne 1033). An expanded version of Franciscus Junius’s (1591–1677) Icelandic wordlist (Bodl. MS Junius 36), itself based on Runólfur Jónsson’s (c.1620–1654)Grammaticae Islandicae Rudimenta(1651), theDictionariolumwas included in George Hickes’ (1642–1715)Institutiones Grammaticae Anglo-Saxonicae et Moeso-Gothicae(1689). Comparison of the manuscript entries with theDictionariolumsuggests that Kennett relied on this work for a portion of the northern material contained in his manuscript. This paper aims to further our knowledge about the compilation of Kennett’s dictionary, casting some light on the sources behind the regional dialect material included, and on the history of northern English lexicon more generally as recorded in 17th-century dictionaries.
On the Possibility of Pidgin English Toponyms in Pacific Missions
Authors: Nash Joshua 
Published: May 2015

Summary
This paper speculates about the possible existence of Pidgin English toponyms on the Melanesian Mission on Norfolk Island. The argument considers why modern historians and linguists studying the social and linguistic history of the Melanesian Mission missionaries, and why missionaries from earlier periods, who were documenting and studying local Melanesian languages spoken within the Mission’s activities, did not provide possible available information on Pidgin English toponyms. This noted absence of an explicit focus on the toponymic lexicon of Pidgin English and other marginalised languages highlights certain metalinguistic and social priorities held by linguists.
Changes in the contents of corporate codes of ethics: an institutional interpretation
Authors: Singh Jang B. 
Published: May 2015

Purpose
– The purpose of this paper was to examine changes in the contents of Canadian corporate codes of ethics over a period of two decades from an institutionalization perspective.

Design/methodology/approach
– The paper tracks changes in the contents of the codes of large Canadian corporations longitudinally by analyzing their contents at two points over two decades, in 1992 and 2012. In particular, the paper tests three hypotheses related to the institutionalization of codes.

Findings
– It was found that the codes have become more prescriptive, they are more concerned with social responsibility and are more likely to identify their moral and legal authority. Overall, the findings support an institutional interpretation of the observed changes.

Research limitations/implications
– While large corporations are critical in establishing new and innovative management practices, their selection as the study population limits the generalizabilty of the findings. Another limitation of this paper is that it used an a priori determined set of items to analyze the contents of the codes and while this was needed to facilitate the comparison across time, it also meant that some important items were not clearly identified.

Originality/value
– Codes of ethics are the foundation of ethics programs in corporations and their contents could be critical in the development of a culture of ethics in corporations. This paper makes a valuable contribution to research on business ethics by analyzing the codes of ethics of the largest corporations in Canada at two points over two decades. The need to track changes in corporate codes of ethics over time has been advocated by several researchers, but longitudinal studies in this area are rare.
Lessons on knowledge creation in supply chain management
Authors: Eriksson David 
Published: May 2015

Purpose– The purpose of this study is to convey lessons learned from a long-term research project and present a coherent approach for researching relevant areas, ranging from ontology to quality.Design/methodology/approach– A PhD process is used as a case to present conceptual ideas on performing research in logistics/supply chain management (SCM).Findings– The research integrates different views on knowledge and the world and how to perform research in logistics/SCM. Models explaining micro and macro abduction, and the relationship between research, the context and researcher subjectivity are suggested.Research limitations/implications– Knowledge on why and how critical realism can be used in logistics/SCM research is advanced. Abduction is presented as a micro/macro process, which should not have any specific “finish line”, and is supported with both ontological and epistemological arguments.Practical implications– Research in logistics/SCM can be improved by connecting different aspects of viewing and creating knowledge. Reflecting on how exactly a publication is related to a project, researchers can better describe how they contribute to knowledge creation, and also understand the relationship between micro and macro abduction.Originality/value– Through presenting an approach to knowledge creation in the context of a PhD thesis, this research distinguishes itself in a field with a growing need to define its own views of the world and of knowledge. The paper advances current understanding of knowledge creation in logistics/SCM, expanding on earlier models and presenting a broader view of the research process and the associated dilemmas. The paper also contains novel considerations of the differences between publication types and how these affect the presentation of the research.
Improving financial services data quality – a financial company practice
Authors: Shi Chuan , Jugulum Rajesh , Joyce Harold Ian , Singh Jagmet , Granese Bob , Ramachandran Raji , Gray Donald , Heien Christopher H , Talburt John R. 
Published: May 2015

Purpose
– This paper aims to propose a funnel methodology that selects business data elements for data quality improvement practices at a financial company. Data quality is crucial in post-crisis recovery of the financial services industry. This allows the bank to monitor its critical data assets and improve its business operation by Six Sigma engagement that benefits from the good quality of data.

Design/methodology/approach
– A funnel methodology is invented. It utilizes a rationalization matrix and statistical methods to identify critical data elements (CDEs) for data quality efforts from numerous candidates across business functions. The “Voice of the Customer” is achieved by including subject matter experts, whose knowledge and experience contribute to the entire process.

Findings
– The methodology eliminates redundancy and reduces the number of data elements to be monitored, so that attention becomes focused on the right elements. In addition, the methodology ensures that the conduct of the data quality assessment is framed within a context of the functional area’s business objectives.

Originality/value
– Measuring and improving data quality form a solid foundation of every Six Sigma engagement. When presented with large data elements, determining what to measure can be an arduous task. Having a proven systematic and valid process to reduce the CDE candidate pool becomes an operational necessity of paramount importance, and this justifies the value of the proposed methodology. Its implementation is described by a Basel II case study. The methodology is not restricted to financial services industry, and can be used readily in any other industry that requires data quality improvement.
Underwater robots: a review of technologies and applications
Authors: Bogue Robert 
Published: May 2015

Purpose
This paper aims to provide details of underwater robot technology and its applications.

Design/methodology/approach
Following an introduction, this article first discusses remotely operated vehicle (ROV) technology and applications and then considers their use in the emerging field of deep-sea mining. It then discusses autonomous underwater vehicle (AUV) technology and its applications, including sub-sea gliders. Finally, brief concluding comments are drawn.

Findings
ROVs were first developed in the 1950s for military applications. They are now widely used by the offshore oil and gas sector and other industries and are being developed for deep-sea mining. AUV technology has progressed rapidly in recent years and AUVs, including sub-sea gliders, are now emerging from their original role in oceanographic research and finding growing uses in the defence and offshore energy sectors.

Originality/value
This provides a detailed insight into underwater robot technologies, products and applications.