bluuebunny/crossref_metadata_2025_split huggingface dataset:
In vivo evaluation of axial integrity of coronary stents using intravascular ultrasound: Insights on longitudinal stent deformation
Authors: Dvir Danny , Kitabata Hironori , Barbash Israel M. , Minha Sa'ar , Badr Salem , Loh Joshua P. , Chen Fang , Torguson Rebecca , Waksman Ron 
Published: November 2013

ObjectiveTo evaluate the axial integrity of different coronary stents using intravascular ultrasound (IVUS).BackgroundLongitudinal stent deformation was recently reported.MethodsConsecutive patients who underwent IVUS analysis after drug‐eluting stent (DES) implantation for de novo coronary lesions were evaluated. Stent length was compared with label length for calculation of absolute change and relative difference (absolute change divided by label length).ResultsA total of 233 DES utilizing five different platforms were included. The median absolute change in stent length was 0.90 mm (interquartile range [IQR] 0.48–1.39) and the relative difference was 5.24% (IQR 2.55–8.29). There was no significant difference among the groups in median absolute or relative change: Cypher 0.89 mm/3.89%, Taxus 0.88 mm/5.39%, Endeavor 1.16 mm/6.77%, Xience V 0.86 mm/5.80%, and PROMUS Element 0.79 mm/5.34% (P = 0.085, P = 0.072, respectively). Multivariate logistic regression revealed that the Cypher stent was independently correlated with a lower change in length, whereas stent label length and deployment pressure were correlated with higher absolute change.ConclusionThe axial integrity of DES platforms examined in vivo was high, with only mild changes in stent length after implantation. While there are differences between first‐ and second‐generation DES, axial integrity among second‐generation DES was similar. © 2013 Wiley Periodicals, Inc.
A combination of plaque components analyzed by integrated backscatter intravascular ultrasound and serum pregnancy‐associated plasma protein a levels predict the no‐reflow phenomenon during percutaneous coronary intervention
Authors: Daidoji Hyuma , Takahashi Hiroki , Otaki Yoichiro , Tamura Harutoshi , Arimoto Takanori , Shishido Tetsuro , Miyashita Takehiko , Miyamoto Takuya , Watanabe Tetsu , Kubota Isao 
Published: November 2013

AimsPrevious studies reported that integrated backscatter intravascular ultrasound (IB‐IVUS) provides high diagnostic accuracy for tissue characterization of coronary plaques and that pregnancy‐associated plasma protein A (PAPP‐A) could be a marker of adverse cardiac outcome in patients with cardiovascular disease. We examined whether IB‐IVUS and PAPP‐A levels could predict the incidence of no‐reflow during percutaneous coronary intervention (PCI)Methods and ResultsAbout 176 consecutive patients (138 men, mean age 68 ± 11 years) who underwent PCI with IB‐IVUS were prospectively enrolled. Combined no‐reflow, including transient filter no‐reflow by using distal protection devices, was observed in 31 patients. The percentages of coronary lipid volume (%LV) analyzed by IB‐IVUS and serum PAPP‐A were significantly higher in patients with combined no‐reflow than normal‐reflow. To predict no‐reflow, a receiver operating characteristic (ROC) analysis determined cut‐off values of %LV as 62% and serum PAPP‐A as 7.71 ng/mL. The multivariate logistic regression analysis showed that %LV (hazard ratio 4.5, 95% confidence interval 1.6–13.4, P < 0.01) and PAPP‐A (hazard ratio 4.32, 95% confidence interval 1.5–12.7, P < 0.01) were independent predictors of combined no‐reflowConclusions%LV analyzed by IB‐IVUS and serum PAPP‐A levels were closely associated with the coronary no‐reflow phenomenon. © 2014 Wiley Periodicals, Inc.
Highly Active Modulators of Indole Signaling Alter Pathogenic Behaviors in Gram‐Negative and Gram‐Positive Bacteria
Authors: Minvielle Marine J. , Eguren Kristen , Melander Christian 
Published: November 2013

AbstractIndole is a universal signal that regulates various bacterial behaviors, such as biofilm formation and antibiotic resistance. To generate mechanistic probes of indole signaling and control indole‐mediated pathogenic phenotypes in both Gram‐positive and Gram‐negative bacteria, we have investigated the use of desformylflustrabromine (dFBr) derivatives to generate highly active indole mimetics. We have developed non‐microbicidal dFBr derivatives that are 27–2000 times more active than indole in modulating biofilm formation, motility, acid resistance, and antibiotic resistance. The activity of these analogues parallels indole, because they are dependent on temperature, the enzyme tryptophanase TnaA, and the transcriptional regulator SdiA. This investigation demonstrates that molecules based on the dFBr scaffold can alter pathogenic behaviors by mimicking indole‐signaling pathways.
Generation of Stoichiometric Ethylene and Isotopic Derivatives and Application in Transition‐Metal‐Catalyzed Vinylation and Enyne Metathesis
Authors: Min Geanna K. , Bjerglund Klaus , Kramer Søren , Gøgsig Thomas M. , Lindhardt Anders T. , Skrydstrup Troels 
Published: November 2013

AbstractEthylene is one of the most important building blocks in industry for the production of polymers and commodity chemicals. 13C‐ and D‐isotope‐labeled ethylenes are also valuable reagents with applications ranging from polymer‐structure determination, reaction‐mechanism elucidation to the preparation of more complex isotopically labeled compounds. However, these isotopic derivatives are expensive, and are flammable gases, which are difficult to handle. We have developed a method for the controlled generation of ethylene and its isotopic variants including, for the first time, fully isotopically labeled ethylene, from simple alkene precursors by using Ru catalysis. Applying a two‐chamber reactor allows both the synthesis of ethylene and its immediate consumption in a chemical transformation permitting reactions to be performed with only stoichiometric amounts of this two carbon olefin. This was demonstrated in the Ni‐catalyzed Heck reaction with aryl triflates and benzyl chlorides, as well as Ru‐mediated enyne metathesis.
ChemInform Abstract: First Evidence of a Phase Transition in a High‐Pressure Metal Iodate: Structural and Thermal Studies of AgIO3 Polymorphs.
Authors: Suffren Yan , Gautier‐Luneau Isabelle , Darie Celine , Goujon Celine , Legendre Murielle , Leynaud Olivier 
Published: November 2013

AbstractA new phase of silver iodate, β‐AgIO3, is obtained by heating α‐AgIO3 at 2.7 GPa at <240 °C for 30 min.
ChemInform Abstract: Transformation of Rutile to TiO2‐II in a High Pressure Hydrothermal Environment.
Authors: Spektor Kristina , Tran Dung Trung , Leinenweber Kurt , Haeussermann Ulrich 
Published: November 2013

AbstractSingle phase bulk samples of the high‐pressure modificationTiO2‐II are obtained from rutile powder under hydrothermal conditions (6 GPa and 650 °C).
ChemInform Abstract: Solvothermal Syntheses, Crystal Structures, and Properties of Lanthanide(III) Thioarsenates [Ln(dien)2(μ‐1ϰ,2ϰ2‐AsS4)] n (Ln: Sm, Eu, Gd) and [Ln(dien)2(1ϰ2‐AsS4)] (Ln: Tb, Dy, Ho).
Authors: Wang Fang , Tang Chunying , Chen Ruihong , Zhang Yong , Jia Dingxian 
Published: November 2013

AbstractSolvothermal reactions of Ln2O3, As and S in diethylenetriamine (dien) (autoclave, 170 °C, 6 d) yields two structural types of lanthanide thioarsenates of general formulae [Ln(dien)2(μ‐1ϰ,2ϰ2‐AsS4)] n (Ln: Sm, Eu, Gd) and [Ln(dien)2(1ϰ2‐AsS4)] (Ln: Tb, Dy, Ho) in 45—57% yield.
ChemInform Abstract: Photocycloaddition of Arenes and Allenes.
Authors: Sreit Ursula , Birbaum Frederic , Quattropani Anna , Bochet Christian G. Bochet Christian G. 
Published: November 2013

AbstractA novel intramolecular para cycloaddition of arenes with allenes yielding bicyclooctadiene‐type products and benzoxepine acetals is presented.
ChemInform Abstract: Simple and Sustainable Iron‐Catalyzed Aerobic C—H Functionalization of N,N‐Dialkylanilines.
Authors: Ratnikov Maxim O. , Xu Xinfang , Doyle Michael P. 
Published: November 2013

AbstractIron(III) chloride catalyzes the aerobic oxidation of tertiary anilines, including N‐aryltetrahydroisoquinolines, to form reactive iminium ion intermediates that undergo Mannich reactions with silyloxyfurans, nitroalkanes, and other nucleophiles to give the corresponding butenolides, nitro compounds, and α‐substituted tetrahydroisoquinolines, respectively.
ChemInform Abstract: Triphenyltin Chloride as a New Source of Phenyl Group for C‐Heteroatom and C—C Bond Formation.
Authors: Iranpoor Nasser , Firouzabadi Habib , Davan Elham Etemadi , Rostami Abed , Nematollahi Arash 
Published: November 2013

AbstractTriphenyltin chloride is used as phenyl group source for the Cu‐catalyzed phenylation of primary and secondary amines, phenols, and thiols.
ChemInform Abstract: A Ligand‐Free Palladium‐Catalyzed Cross‐Coupling of Aryl Sulfinates with Aryl Bromides.
Authors: Ortgies Dirk H. , Forgione Pat 
Published: November 2013

AbstractA ligand free Pd‐catalyzed process is presented to allow the synthesis of biphenyls by desulfinylative cross‐coupling of aryl sulfinates with aryl bromides.
ChemInform Abstract: Reversal of Polarity in Masked o‐Benzoquinones: Rapid Access to Unsymmetrical Oxygenated Biaryls.
Authors: Parumala Santosh Kumar Reddy , Peddinti Rama Krishna 
Published: November 2013

Abstract6,6‐Dimethoxycyclohexa‐2,4‐dienones commonly known as masked o‐benzoquinones are prepared in situ from guaiacol derivatives.
ChemInform Abstract: Catalytic Epoxidation Activity of Keplerate Polyoxomolybdate Nanoball Toward Aqueous Suspension of Olefins under Mild Aerobic Conditions.
Authors: Rezaeifard Abdolreza , Haddad Reza , Jafarpour Maasoumeh , Hakimi Mohammad 
Published: November 2013

AbstractThe catalytic efficiency of a sphere‐shaped nanosized polyoxomolybdate in the aerobic epoxidation of olefins in water is studied.
ChemInform Abstract: Direct Catalytic Asymmetric Vinylogous Mannich‐Type Reaction of γ‐Butenolides with Ketimines.
Authors: Yin Liang , Takada Hisashi , Kumagai Naoya , Shibasaki Masakatsu 
Published: November 2013

AbstractThe activation of the N‐thiophosphinoyl group by a mild Lewis acid is the key to achieve the enantioselective title reaction.
ChemInform Abstract: Zinc‐Mediated Asymmetric Allylation of Chiral N‐tert‐Butanesulfinyl Aldimines with 3‐Bromomethyl‐5H‐furan‐2‐one.
Authors: Shen An , He Zhi‐Tao , Yu Hong‐Jie , Fukui Yuki , Tian Ping , Lin Guo‐Qiang 
Published: November 2013

AbstractThe title reaction provides predominantly the anti‐isomers (III) with excellent diastereoselectivity with anti/syn ratios in the range of 5:1 up to 18:1.
ChemInform Abstract: Carbonylation of Propargyl Carbamates with Palladium(II) Bisoxazoline Catalysts: Efficient Synthesis of 5‐Methoxy‐3(2H)‐furanones.
Authors: Kusakabe Taichi , Takahashi Takeo , Shen Rong , Ikeda Ayumi , Dhage Yogesh Daulat , Kanno Yuichro , Inouye Yoshio , Sasai Hiroaki , Mochida Tomoyuki , Kato Keisuke 
Published: November 2013

AbstractThis reaction is influenced by a gem‐dialkyl effect.
ChemInform Abstract: Indium‐Mediated One‐Pot Pyrrole Synthesis from Nitrobenzenes and 1,4‐Diketones.
Authors: Lee Hyunseung , Kim Byeong Hyo 
Published: November 2013

AbstractA convenient one‐pot procedure is developed for the synthesis of pyrroles via reduction of nitrobenzenes, imine formation and acetic acid promoted intramolecular cyclization.
ChemInform Abstract: anti‐Markovnikov Hydroamination of Alkenes Catalyzed by an Organic Photoredox System.
Authors: Nguyen Tien M. , Nicewicz David A. 
Published: November 2013

AbstractThe photochemical reaction of the amine substrates does not require any metal catalyst and is effective in the presence of 9‐mesityl‐10‐methylacridinium tetrafluoroborate and thiophenol as a hydrogen donor.
ChemInform Abstract: Cp*CoIII‐Catalyzed C2‐Selective Addition of Indoles to Imines.
Authors: Yoshino Tatsuhiko , Ikemoto Hideya , Matsunaga Shigeki , Kanai Motomu 
Published: November 2013

AbstractThe utility of a Co(III) catalyst to promote the C2‐selective addition of indoles to imines is demonstrated.
ChemInform Abstract: Carbocyclization versus Oxycyclization on the Metal‐Catalyzed Reactions of Oxyallenyl C3‐Linked Indoles.
Authors: Alcaide Benito , Almendros Pedro , Alonso Jose M. , Fernandez Israel 
Published: November 2013

AbstractPreviously unknown (indol‐3‐yl)‐α‐allenols (III) are prepared from indole‐3‐carbaldehydes by indium‐mediated Barbier allenylation reaction taking advantage of the N‐(2‐pyridyl)sulfonyl group.
ChemInform Abstract: Synthesis and Antimicrobial Activity of Azetidin‐2‐one Containing Pyrazoline Derivatives.
Authors: Shah Shailesh H. , Patel Pankaj S. 
Published: November 2013

AbstractA new series of azetidinone‐containing pyrazoline derivatives (VIII) (10 examples, yields not given) are synthesized and evaluated for their antimicrobial activities.
ChemInform Abstract: A New Life for an Old Reagent: Fluoroalkyl Amino Reagents as Efficient Tools for the Synthesis of Diversely Fluorinated Pyrazoles.
Authors: Pazenok Sergiy , Giornal Florence , Landelle Gregory , Lui Norbert , Vors Jean‐Pierre , Leroux Frederic R. 
Published: November 2013

AbstractThe first practical method for the regioselective synthesis of the title compounds is developed.
ChemInform Abstract: Synthesis and Antioxidant Activity of a Variety of Sulfonamidomethane Linked 1,3,4‐Oxadiazoles and Thiadiazoles.
Authors: Swapna Mukkara , Premakumari Chokkappagari , Reddy Sanapalli Nagi , Padmaja Adivireddy , Padmavathi Venkatapuram 
Published: November 2013

AbstractA new class of sulfonamidomethane linked oxadiazoles and thiadiazoles is prepared.
ChemInform Abstract: In situ Catalytic Generation of Allylcopper Species for Asymmetric Allylation: Toward 1H‐Isochromene Skeletons.
Authors: Kawai Junya , Chikkade Prasanna Kumara , Shimizu Yohei , Kanai Motomu 
Published: November 2013

AbstractThe minimal‐waste‐producing allylcopper generation method tolerates free hydroxy groups [e.g. (VIg)].
ChemInform Abstract: Tetrahydropyrido[d]pyridazinones‐Promising Scaffolds for Drug Discovery.
Authors: Yaremenko Anatoliy G. , Volochnyuk Dmitriy M. , Shelyakin Vyacheslav V. , Grygorenko Oleksandr O. 
Published: November 2013

AbstractThe synthesis of all four possible title compounds can be achieved from pyridines of type (I).
ChemInform Abstract: Multicomponent Synthesis of 4‐Aminophthalazin‐1(2H)‐ones by Palladium‐Catalyzed Isocyanide Insertion.
Authors: Vlaar Tjoestil , Mampuys Pieter , Helliwell Madeleine , Maes Bert U. W. , Orru Romano V. A. , Ruijter Eelco 
Published: November 2013

AbstractA new method for the synthesis of biologically interesting aminophthalazinones is presented.
ChemInform Abstract: Synthesis and Study of Antibacterial and Antifungal Activities of Some New Hydroxychalcone‐Based Azo Dyes.
Authors: Baseer Muhammad , Saeed Aamer , Samra Shahid A. , Ashraf Zaman , Ansari Farzana L. 
Published: November 2013

AbstractNovel hydroxychalcone azo dyes and related bis azo dyes are synthesized by reaction of chalcones with aniline diazonium salts.
Entrepreneurs and the context of cooperative organizations: A definition of cooperative entrepreneur
Authors: Diaz‐Foncea Millán , Marcuello Carmen 
Published: November 2013

AbstractWe focus on the role of entrepreneurs in organizations that are structured as cooperatives. In considering the similarities and differences among various forms of entrepreneurship, a comprehensive definition of the cooperative entrepreneur is formulated. A model illustrating four variations in the manner in which cooperative entrepreneurship contributes to the creation of cooperatives is also presented. These contributions help to more clearly frame future research and lend visibility to the challenges faced by entrepreneurs in the cooperative context. Copyright © 2013 ASAC. Published by John Wiley & Sons, Ltd.
Effect of the Side‐Chain‐Distribution Density on the Single‐Conjugated‐Polymer‐Chain Conformation
Authors: Hu Zhongjian , Adachi Takuji , Lee Young‐Gi , Haws Ryan T. , Hanson Benjamin , Ono Robert J. , Bielawski Christopher W. , Ganesan Venkat , Rossky Peter J. , Vanden Bout David A. 
Published: November 2013

AbstractThe spatial arrangement of the side chains of conjugated polymer backbones has critical effects on the morphology and electronic and photophysical properties of the corresponding bulk films. The effect of the side‐chain‐distribution density on the conformation at the isolated single‐polymer‐chain level was investigated with regiorandom (rra‐) poly(3‐hexylthiophene) (P3HT) and poly(3‐hexyl‐2,5‐thienylene vinylene) (P3HTV). Although pure P3HTV films are known to have low fluorescence quantum efficiencies, we observed a considerable increase in fluorescence intensity by dispersing P3HTV in poly(methyl methacrylate) (PMMA), which enabled a single‐molecule spectroscopy investigation. With single‐molecule fluorescence excitation polarization spectroscopy, we found that rra‐P3HTV single molecules form highly ordered conformations. In contrast, rra‐P3HT single molecules, display a wide variety of different conformations from isotropic to highly ordered, were observed. The experimental results are supported by extensive molecular dynamics simulations, which reveal that the reduced side‐chain‐distribution density, that is, the spaced‐out side‐chain substitution pattern, in rra‐P3HTV favors more ordered conformations compared to rra‐P3HT. Our results demonstrate that the distribution of side chains strongly affects the polymer‐chain conformation, even at the single‐molecule level, an aspect that has important implications when interpreting the macroscopic interchain packing structure exhibited by bulk polymer films.
Levoglucosan Formation from Crystalline Cellulose: Importance of a Hydrogen Bonding Network in the Reaction
Authors: Hosoya Takashi , Sakaki Shigeyoshi 
Published: November 2013

AbstractLevoglucosan (1,6‐anhydro‐β‐D‐glucopyranose) formation by the thermal degradation of native cellulose was investigated by MP4(SDQ)//DFT(B3LYP) and DFT(M06‐2X)//DFT(B3LYP) level computations. The computational results of dimer models lead to the conclusion that the degradation occurs by a concerted mechanism similar to the degradation of methyl β‐D‐glucoside reported in our previous study. One‐chain models of glucose hexamer, in which the interchain hydrogen bonds of real cellulose crystals are absent, do not exhibit the correct reaction behavior of levoglucosan formation; for instance, the activation enthalpy (Ea=≈38 kcal mol−1) is considerably underestimated compared to the experimental value (48–60 kcal mol−1). This problem is solved with the use of two‐chain models that contain interchain hydrogen bonds. The theoretical study of this model clearly shows that the degradation of the internal glucosyl residue leads to the formation of a levoglucosan precursor at the chain end and levoglucosan is selectively formed from this levoglucosan end. The calculated Ea (56–62 kcal mol−1) agrees well with the experimental value. The computational results of three‐chain models indicate that this degradation occurs selectively on the crystalline surface. All these computational results provide a comprehensive understanding of several experimental facts, the mechanisms of which have not yet been elucidated.
Palladium‐Catalyzed Domino Double N‐Arylations (Inter‐ and Intramolecular) of 1,2‐Diamino(hetero)arenes with o,o′‐Dihalo(hetero)arenes for the Synthesis of Phenazines and Pyridoquinoxalines
Authors: Laha Joydev K. , Tummalapalli K. S. Satyanarayana , Gupta Ankur 
Published: November 2013

AbstractDomino reactions for the synthesis of phenazines have been developed that start from 1,2‐diaminoarenes and 1,2‐dihaloarenes and proceed through palladium‐catalyzed double N‐arylations (inter‐ and intramolecular) followed by an in situ oxidation. A variety of functional groups, which include base‐sensitive groups, were well tolerated under the optimized reaction conditions to afford phenazines in good to excellent yields. The protocol was extended to the synthesis of pyridoquinoxalines by employing either o‐phenylenediamines and 2,3‐dihalopyridines or 1,2‐diaminopyridines and 1,2‐dihaloarenes.
Indoxylic Acid Esters as Convenient Intermediates Towards Indoxyl Glycosides
Authors: Böttcher Stephan , Thiem Joachim 
Published: November 2013

AbstractIndoxylic acid methyl and allyl esters with varied halide‐substitution patterns were obtained in excellent yields using a scalable route. Phase‐transfer glycosylation of these key intermediates was carried out with various glycosyl halides. Subsequent mild silver‐mediated decarboxylation followed by Zemplén deacetylation led to indoxyl glycosides in good overall yields. Indoxyl glycosides are well‐established and widely used tools for enzyme screening and enzyme‐activity monitoring. In the past, their synthesis has been difficult, so this new approach has led to a variety of useful structures.
(D,L)‐10‐Camphorsulfonic‐Acid‐Catalysed Synthesis of Diaryl‐Fused 2,8‐Dioxabicyclo[3.3.1]nonanes from 2‐Hydroxychalcones and Naphthol Derivatives
Authors: Jiang Xiaolong , Song Zilan , Xu Chang , Yao Qizheng , Zhang Ao 
Published: November 2013

AbstractA tandem one‐pot Friedel–Crafts alkylation/double cyclization process to conveniently assemble diaryl‐fused 2,8‐dioxabicyclo[3.3.1]nonanes with aryl substituents at the C‐1 position was developed. 2‐Hydroxychalcones and naphthol derivatives reacted in refluxing toluene with (D,L)‐10‐camphorsulfonic acid (CSA) as the catalyst. The transformation conveniently provided the corresponding 2,8‐dioxabicyclo[3.3.1]nonanes fused with one phenyl and one naphthyl group in moderate to good yields, and various substitutions on both reaction partners were tolerated. More importantly, aryl‐ and aza‐aryl‐fused 2,8‐dioxabicyclo[3.3.1]nonanes were prepared for the first time using this procedure.
Incorporating intensity bounds for assessing the seismic safety of structures: Does it matter?
Authors: Lazar Nuša , Dolšek Matjaž 
Published: November 2013

SUMMARYThe closed‐form solution for assessing the proportion of the mean annual frequency of limit‐state exceedance as a function of integration limits is introduced, in order to study whether or not the mean annual frequency of limit‐state exceedance is overestimated if the lower and(or) upper integration limit of the risk equation are(is) not selected in a physically consistent manner. Simple formulas for assessing the threshold value of the lower and upper integration limits are also derived. These formulas can be used to quickly assess the significant range of ground motion intensity that affects the mean annual frequency of limit‐state exceedance. It is shown that the threshold values of the integration limits depend on the median intensity causing a limit‐state, the corresponding dispersion and the slope of the hazard curve in the log domain. For several reinforced concrete buildings located in a region with moderate seismicity, it is demonstrated that the mean annual frequency of collapse can be significantly overestimated when assessed by integrating the risk equation over the entire range of ground motion intensity. Copyright © 2013 John Wiley & Sons, Ltd.