bluuebunny/crossref_metadata_2025_split huggingface dataset:
HIV Infection Is Associated with Impaired Striatal Function during Inhibition with Normal Cortical Functioning on Functional MRI
Authors: du Plessis Stéfan , Vink Matthijs , Joska John A. , Koutsilieri Eleni , Bagadia Asif , Stein Dan J , Emsley Robin 
Published: October 2015

AbstractThe aim of the present study was to investigate the effect of HIV infection on cortical and subcortical regions of the frontal-striatal system involved in the inhibition of voluntary movement. Functional MRI (fMRI) studies suggest that human immunodeficiency virus (HIV) infection is associated with frontostriatal dysfunction. While frontostriatal systems play a key role in behavioral inhibition, there are to our knowledge no fMRI studies investigating the potential impact of HIV on systems involved during the inhibition of voluntary movement. A total of 17 combined antiretroviral therapy (cART) naïve HIV+ participants as well as 18 age, gender, ethnic, education matched healthy controls performed a modified version of the stop-signal paradigm. This paradigm assessed behavior as well as functional brain activity associated with motor execution, reactive inhibition (outright stopping) and proactive inhibition (anticipatory response slowing before stopping). HIV+ participants showed significantly slower responses during motor execution compared to healthy controls, whereas they had normal proactive response slowing. Putamen hypoactivation was evident in the HIV+ participants based on successful stopping, indicating subcortical dysfunction during reactive inhibition. HIV+ participants showed normal cortical functioning during proactive inhibition. Our data provide evidence that HIV infection is associated with subcortical dysfunction during reactive inhibition, accompanied by relatively normal higher cortical functioning during proactive inhibition. This suggests that HIV infection may primarily involve basic striatal-mediated control processes in cART naïve participants. (JINS, 2015, 21, 722–731)
Nutrition for homeless populations: shelters and soup kitchens as opportunities for intervention
Authors: Koh Katherine A , Bharel Monica , Henderson David C 
Published: October 2015

AbstractNutrition is a daily challenge for the homeless population in America. Homeless individuals suffer from a high prevalence of diseases related to poor diet, yet there has been little public health effort to improve nutrition in this population. Shelters and soup kitchens may have an untapped potential to impact food access, choice and quality. We offer ideas for intervention and lessons learned from ten shelters and soup kitchens around Greater Boston, MA, USA. By advancing food quality, education and policies in shelters and soup kitchens, the homeless population can be given an opportunity to restore its nutrition and health.
Linoleic acid and breast cancer risk: a meta-analysis
Authors: Zhou Yunping , Wang Tao , Zhai Shenyong , Li Wei , Meng Qiang 
Published: October 2015

AbstractObjectivePrior studies on linoleic acid, the predominantn-6 fatty acid, and breast cancer risk have generated inconsistent results. We performed a meta-analysis to summarize the evidence regarding the relationship of dietary and serum linoleic acid with breast cancer risk.DesignPertinent studies were identified by a search of PubMed and EMBASE. The fixed- or random-effect pooled measure was selected based on between-study heterogeneity.ResultsEight prospective cohort studies and four prospective nested case–control studies, involving 10 410 breast cancer events from 358 955 adult females across different countries, were included in present study. Compared with the lowest level of linoleic acid, the pooled relative risk (RR; 95 % CI) of breast cancer was 0·98 (0·93, 1·04) for the highest level of linoleic acid. The pooled RR (95 % CI) for dietary and serum linoleic acid were 0·99 (0·92, 1·06) and 0·98 (0·88, 1·08), respectively. The RR (95 % CI) of breast cancer was 0·97 (0·91, 1·04), 0·95 (0·85, 1·07), 0·96 (0·86, 1·07), 0·98 (0·87, 1·10) and 0·99 (0·85, 1·14) for linoleic acid intake of 5, 10, 15, 20 and 25 g/d, respectively. The risk of breast cancer decreased by 1 % (RR=0·99; 95 % CI 0·93, 1·05) for every 10 g/d increment in linoleic acid intake.ConclusionsThis meta-analysis indicated that both dietary linoleic acid intake and serum linoleic acid level were associated with decreased risk of breast cancer, although none of the associations were statistically significant. Further investigations are warranted.
Mineralogical determination in situ of a highly heterogeneous material using a miniaturized laser ablation mass spectrometer with high spatial resolution
Authors: Neubeck Anna , Tulej Marek , Ivarsson Magnus , Broman Curt , Riedo Andreas , McMahon Sean , Wurz Peter , Bengtson Stefan 
Published: October 2015

AbstractTechniques enabling in situ elemental and mineralogical analysis on extraterrestrial planets are strongly required for upcoming missions and are being continuously developed. There is ample need for quantitative and high-sensitivity analysis of elemental as well as isotopic composition of heterogeneous materials. Here we present in situ spatial and depth elemental profiles of a heterogeneous rock sample on a depth-scale of nanometres using a miniaturized laser ablation mass spectrometer (LMS) designed for planetary space missions. We show that the LMS spectra alone could provide highly detailed compositional, three-dimensional information and oxidation properties of a natural, heterogeneous rock sample. We also show that a combination of the LMS and Raman spectroscopy provide comprehensive mineralogical details of the investigated sample. These findings are of great importance for future space missions where quick, in situ determination of the mineralogy could play a role in the process of selecting a suitable spot for drilling.
Non-Western national music and empire in global history: interactions, uniformities, and comparisons
Authors: van der Linden Bob 
Published: October 2015

AbstractInspired by C. A. Bayly’s notion of global uniformities, this article investigates the different ways in which elitist non-Western music reformers, often with state support, canonized and institutionalized modern national music traditions during the age of liberalism and empire. As these non-Western music reformers reinterpreted liberal and earlier Enlightenment ideas, they envisaged their own musics hierarchically in comparison with Western music. In the context of comparative musicological thinking, they became particularly preoccupied with the systematization of scales, equal temperament tuning, and the origins of their own music. In the process, they often incorporated claims about authenticity and spirituality in music to give strength to burgeoning national, if not anti-imperial, identities. However, beneath the appearance of formal similarity and mutual translatability of non-Western national musics, significant sonic and cultural differences remained. As a contribution to global history scholarship, the article principally attempts to establish these global parallels and comparisons.
‘Ireland’s sister nations’: internationalism and sectarianism in the Irish struggle for independence, 1916–22
Authors: Rast M. C. 
Published: October 2015

AbstractFollowing the First World War, nationalists in several parts of the British empire amplified their calls for greater self-government. Activists in Egypt, India, and Ireland portrayed themselves as representatives of movements for national self-determination. Their opponents countered that religious divisions undermined these groups’ claims to nationhood, making the presence of an outside power necessary to protect minorities. Activists formed networks and positioned themselves as parts of a worldwide anti-imperialist movement. Their opponents used these ties in attempts to portray separatist movements as foreign-inspired and socialist. Irish republicans and their global counterparts also struggled with accusations of sectarianism as they advanced their independence claims. This article examines Irish republicans’ connections with international revolutionaries. The confluence of political and religious identities there and in other parts of the British empire provided a pretext for continued imperial engagement. Partition forced nationalists to adjust to new geographic and demographic realities in their post-independence states.
Establishing a Governmental Duty of Care for Climate Change Mitigation: WillUrgendaTurn the Tide?
Authors: van Zeben Josephine 
Published: October 2015

AbstractLiability for causing or failing to mitigate climate change has long been proposed as an alternative, or backstop, to lagging international cooperation. Thus far, there has been very limited success in holding governments or individuals responsible for the emission of greenhouse gases (GHGs) that are considered the primary cause of anthropogenic climate change. The recent landmark decision inUrgenda Foundationv.Government of the Netherlands (Ministry of Infrastructure and the Environment)breaks with this tradition. In June 2015, the Dutch District Court (The Hague) held that the current climate policies of the government are not sufficiently ambitious for it to fulfil its duty of care towards Dutch society. The judgment, and the accompanying order for the government to adopt stricter GHG reduction policies, raises important questions about the future of climate change liability litigation, the separation of powers between the judiciary and the legislature, and the effect of litigation on international climate change negotiation and cooperation.
DNMT3A mutations mediate the epigenetic reactivation of the leukemogenic factor MEIS1 in acute myeloid leukemia
Authors: Ferreira H J , Heyn H , Vizoso M , Moutinho C , Vidal E , Gomez A , Martínez-Cardús A , Simó-Riudalbas L , Moran S , Jost E , Esteller M 
Published: October 2015

Abstract
Close to half of de novo acute myeloid leukemia (AML) cases do not exhibit any cytogenetic aberrations. In this regard, distortion of the DNA methylation setting and the presence of mutations in epigenetic modifier genes can also be molecular drivers of the disease. In recent years, somatic missense mutations of the DNA methyltransferase 3A (DNMT3A) have been reported in ~20% of AML patients; however, no obvious critical downstream gene has been identified that could explain the role of DNMT3A in the natural history of AML. Herein, using whole-genome bisulfite sequencing and DNA methylation microarrays, we have identified a key gene undergoing promoter hypomethylation-associated transcriptional reactivation in DNMT3 mutant patients, the leukemogenic HOX cofactor MEIS1. Our results indicate that, in the absence of mixed lineage leukemia fusions, an alternative pathway for engaging an oncogenic MEIS1-dependent transcriptional program can be mediated by DNMT3A mutations.
Linkage and regional association analysis reveal two new tightly-linked major-QTLs for pod number and seed number per pod in rapeseed (Brassica napus L.)
Authors: Shi Jiaqin , Zhan Jiepeng , Yang Yuhua , Ye Jiang , Huang Shunmou , Li Ruiyuan , Wang Xinfa , Liu Guihua , Wang Hanzhong 
Published: October 2015

AbstractTo facilitate the pseudochromosomes assembly and gene cloning in rapeseed, we developed a reference genetic population/map (named BnaZNF2) from two sequenced cultivars, Zhongshuang11 and No.73290, those exhibit significant differences in many traits, particularly yield components. The BnaZNF2 genetic map exhibited perfect collinearity with the physical map of B. napus, indicating its high quality. Comparative mapping revealed several genomic rearrangements between B. napus and B. rapa or B. oleracea. A total of eight and 16 QTLs were identified for pod number and seed number per pod, respectively and of which three and five QTLs are identical to previously identified ones, whereas the other five and 11 are novel. Two new major QTL respectively for pod number and seed number per pod, qPN.A06-1 and qSN.A06-1 (R2 = 22.8% and 32.1%), were colocalised with opposite effects and only qPN.A06-1 was confirmed and narrowed by regional association analysis to 180 kb including only 33 annotated genes. Conditional QTL analysis and subsequent NILs test indicated that tight linkage, rather than pleiotropy, was the genetic causation of their colocalisation. Our study demonstrates potential of this reference genetic population/map for precise QTL mapping and as a base for positional gene cloning in rapeseed.
Design and fabrication of a metastable β-type titanium alloy with ultralow elastic modulus and high strength
Authors: Guo Shun , Meng Qingkun , Zhao Xinqing , Wei Qiuming , Xu Huibin 
Published: October 2015

AbstractTitanium and its alloys have become the most attractive implant materials due to their high corrosion resistance, excellent biocompatibility and relatively low elastic modulus. However, the current Ti materials used for implant applications exhibit much higher Young’s modulus (50 ~ 120 GPa) than human bone (~30 GPa). This large mismatch in the elastic modulus between implant and human bone can lead to so-called “stress shielding effect” and eventual implant failure. Therefore, the development of β-type Ti alloys with modulus comparable to that of human bone has become an ever more pressing subject in the area of advanced biomedical materials. In this study, an attempt was made to produce a bone-compatible metastable β-type Ti alloy. By alloying and thermo-mechanical treatment, a metastable β-type Ti-33Nb-4Sn (wt. %) alloy with ultralow Young’s modulus (36 GPa, versus ~30 GPa for human bone) and high ultimate strength (853 MPa) was fabricated. We believe that this method can be applied to developing advanced metastable β-type titanium alloys for implant applications. Also, this approach can shed light on design and development of novel β-type titanium alloys with large elastic limit due to their high strength and low elastic modulus.
A path to practical Solar Pumped Lasers via Radiative Energy Transfer
Authors: Reusswig Philip D. , Nechayev Sergey , Scherer Jennifer M. , Hwang Gyu Weon , Bawendi Moungi G. , Baldo Marc. A. , Rotschild Carmel 
Published: October 2015

AbstractThe optical conversion of incoherent solar radiation into a bright, coherent laser beam enables the application of nonlinear optics to solar energy conversion and storage. Here, we present an architecture for solar pumped lasers that uses a luminescent solar concentrator to decouple the conventional trade-off between solar absorption efficiency and the mode volume of the optical gain material. We report a 750-μm-thick Nd3+-doped YAG planar waveguide sensitized by a luminescent CdSe/CdZnS (core/shell) colloidal nanocrystal, yielding a peak cascade energy transfer of 14%, a broad spectral response in the visible portion of the solar spectrum and an equivalent quasi-CW solar lasing threshold of 23 W-cm−2, or approximately 230 suns. The efficient coupling of incoherent, spectrally broad sunlight in small gain volumes should allow the generation of coherent laser light from intensities of less than 100 suns.
Enhancement of the Si p-n diode NIR photoresponse by embedding β-FeSi2 nanocrystallites
Authors: Shevlyagin A. V. , Goroshko D. L. , Chusovitin E. A. , Galkin K. N. , Galkin N. G. , Gutakovskii A. K. 
Published: October 2015

AbstractBy using solid phase epitaxy of thin Fe films and molecular beam epitaxy of Si, ap+-Si/p-Si/β-FeSi2nanocrystallites/n-Si(111) diode structure was fabricated. Transmission electron microscopy data confirmed a well-defined multilayered structure with embedded nanocrystallites of two typical sizes: 3–4 and 15–20 nm and almost coherent epitaxy of the nanocrystallites with the Si matrix. The diode at zero bias conditions exhibited a current responsivity of 1.7 mA/W, an external quantum efficiency of about 0.2% and a specific detectivity of 1.2 × 109 cm × Hz1/2/W at a wavelength of 1300 nm at room temperature. In the avalanche mode, the responsivity reached up to 20 mA/W (2% in terms of efficiency) with a value of avalanche gain equal to 5. The data obtained indicate that embedding of β-FeSi2nanocrystallites into the depletion region of the Sip-njunction results in expansion of the spectral sensitivity up to 1600 nm and an increase of the photoresponse by more than two orders of magnitude in comparison with a conventional Sip-njunction. Thereby, fabricated structure combines advantage of the silicon photodiode functionality and simplicity with near infrared light detection capability of β-FeSi2.
901 nm Lithographic vertical‐cavity surface‐emitting laser with stable single‐lobed beam pattern
Authors: Li M. , Yang X. , Zhang Y. , Zhao G. , Beadsworth J. , Eifert L. , Tucker F. , Deppe D.G. 
Published: October 2015

Data are presented on 901 nm lithographic vertical‐cavity surface‐emitting lasers (VCSELs) demonstrating high efficiency for small VCSEL sizes, and stable beam patterns. Power conversion efficiency >40% is obtained for VCSELs ranging in size from 6 to 2 µm diameter. The 2 µm diameter VCSELs produce output powers in excess of 6.5 mW, and produce single‐lobed far‐field radiation patterns over the full range of operation.
90Y-daclizumab, an anti-CD25 monoclonal antibody, provided responses in 50% of patients with relapsed Hodgkin’s lymphoma
Authors: Janik John E. , Morris John C. , O’Mahony Deirdre , Pittaluga Stefania , Jaffe Elaine S. , Redon Christophe E. , Bonner William M. , Brechbiel Martin W. , Paik Chang H. , Whatley Millie , Chen Clara , Lee Jae-Ho , Fleisher Thomas A. , Brown Maggie , White Jeffrey D. , Stewart Donn M. , Fioravanti Suzanne , Lee Cathryn C. , Goldman Carolyn K. , Bryant Bonita R. , Junghans Richard P. , Carrasquillo Jorge A. , Worthy Tat’Yana , Corcoran Erin , Conlon Kevin C. , Waldmann Thomas A. 
Published: October 2015

SignificanceDespite advances, a significant proportion of patients with Hodgkin’s lymphoma (HL) will not respond or will relapse. We demonstrated that up to seven infusions of90Y-daclizumab, an anti-CD25–directed monoclonal antibody, provided responses in 50% of patients with relapsed HL. The daclizumab was directed primarily not at tumor cells themselves but toward nonmalignant T cells rosetting around the Reed–Sternberg cells.90Y provided strong β emissions that killed antigen-nonexpressing tumor cells at a distance by a crossfire effect. Furthermore, the strong β irradiation killed normal cells in the tumor microenvironment that nurture the malignant cells in the lymphomatous mass. Therefore90Y-daclizumab infusions provide meaningful therapy for select HL patients.
Retracted: Interaction of Thermus thermophilus ArsC enzyme and gold nanoparticles naked-eye assays speciation between As(III) and As(V)
Authors: Politi Jane , Spadavecchia Jolanda , Fiorentino Gabriella , Antonucci Immacolata , Casale Sandra , De Stefano Luca 
Published: October 2015

Abstract
The thermophilic bacterium Thermus thermophilus HB27 encodes chromosomal arsenate reductase (TtArsC), the enzyme responsible for resistance to the harmful effects of arsenic. We report on adsorption of TtArsC onto gold nanoparticles for naked-eye monitoring of biomolecular interaction between the enzyme and arsenic species. Synthesis of hybrid biological–metallic nanoparticles has been characterized by transmission electron microscopy (TEM), ultraviolet-visible (UV–vis), dynamic light scattering (DLS) and phase modulated infrared reflection absorption (PM-IRRAS) spectroscopies. Molecular interactions have been monitored by UV–vis and Fourier transform-surface plasmon resonance (FT-SPR). Due to the nanoparticles’ aggregation on exposure to metal salts, pentavalent and trivalent arsenic solutions can be clearly distinguished by naked-eye assay, even at 85 μM concentration. Moreover, the assay shows partial selectivity against other heavy metals.
Bans vs. Fees: Disposable Carryout Bag Policies and Bag Usage
Authors: Taylor Rebecca L. , Villas‐Boas Sofia B. 
Published: October 2015

AbstractUsing observational data on consumer carryout bag usage, we measure the effects of disposable bag policies on disposable and reusable bag demand. Our results show that plastic bag bans coupled with paper bag fees decrease total disposable bag demand but lead to significant increases in paper bag consumption. We compare our results to a study on bag fees and find that both policies lead to similar increases in reusable bag usage. However, the success of bans versus fees in discouraging disposable bag usage is contingent upon the types and prices of bags that stores choose to sell in lieu of disposable plastic.
Malignancies in bullous pemphigoid: A controversial association
Authors: Balestri Riccardo , Magnano Michela , La Placa Michelangelo , Patrizi Annalisa , Angileri Luisa , Tengattini Vera , Bardazzi Federico 
Published: October 2015

AbstractBullous pemphigoid (BP) is an autoimmune subepidermal blistering disorder that has been reported to be associated with malignancies. Some authors described several cases of pemphigoid associated with malignancies (PAM); however, the evidence of this correlation still remains controversial. Several theories have been postulated to explain the relationship between malignant neoplasms and BP; the main theory suggests that antibodies directed against tumor‐specific antigens of malignant cells may cross‐react with antigens (like BP antigens) in the basement membrane zone leading to the formation of blisters. We performed an extensive review of the English published work focusing on the epidemiology, the pathogenetic theories and the clinical and histological aspects of the disease. We identified 40 cases of PAM: of these, seven cases were associated with hematological malignancies and 33 with solid tumors. Physicians should be aware of the existence of PAM and we suggest an oncological screening in early‐onset pemphigoid, in patients with a former oncological history, in those with signs and symptoms that could be related to a neoplasm and in BP refractory to common immunosuppressive therapy.
On reflexivity and the conduct of the self in everyday life: reflections on Bourdieu and Archer
Authors: Akram Sadiya , Hogan Anthony 
Published: October 2015

AbstractThis article provides a critique of the concept of reflexivity in social theory today and argues against the tendency to define agency exclusively in terms of reflexivity. Margaret Archer, in particular, is highlighted as a key proponent of this thesis. Archer argues that late modernity is characterized by reflexivity but, in our view, this position neglects the impact of more enduring aspects of agency, such as the routinization of social life and the role of the taken‐for‐granted. These concepts were pivotal to Bourdieu and Giddens' theorization of everyday life and action and to Foucault's understanding of technologies of the self. We offer Bourdieu's habitus as a more nuanced approach to theorizing agency, and provide an alternative account of reflexivity. Whilst accepting that reflexivity is a core aspect of agency, we argue that it operates to a backdrop of the routinization of social life and operates from within and not outside of habitus. We highlight the role of the breach in reflexivity, suggesting that it opens up a critical window for agents to initiate change. The article suggests caution in over‐ascribing reflexivity to agency, instead arguing that achieving reflexivity and change is a difficult and fraught process, which has emotional and moral consequences. The effect of this is that people often prefer the status quo, rather than to risk change and uncertainty.