bluuebunny/crossref_metadata_2025_split huggingface dataset:
Kososan, but not milnacipran, elicits antidepressant‐like effects in a novel psychological stress‐induced mouse model of depression
Authors: Hori Atsushi , Ito Naoki , Oikawa Tetsuro , Hanawa Toshihiko 
Published: January 2015

ABSTRACTAimMild or moderate depressive symptoms are often resistant to treatment with currently available antidepressants. We constructed a novel animal model of depression induced by the exposure of mice to psychological stress and evaluated the antidepressant efficacy of kososan and milnacipran.MethodsDepressive state was elicited in mice by repeated rat‐exposure stress over 10 days. Kososan or milnacipran were administered orally during the stress paradigm. Alterations in behavioral indices (evaluated using forced swimming test and open‐field test), cell proliferation (evaluated on bromodeoxyuridine immunohistochemistry), and orexin‐A production were evaluated.ResultsMice exposed to psychological stress had increased immobility time on forced swimming test, and elevated serum corticosterone. Additionally, decreased bodyweight gain during the stress exposure and reduced food or water intake following the stress were observed. Although oral kososan improved the immobility time on forced swimming test without affecting the locomotor activity in open‐field test, treatment with milnacipran did not alter the immobility time. The number of cells staining positive for bromodeoxyuridine in the dentate gyrus or for orexin‐A in the lateral hypothalamic area was not affected by the stress exposure.ConclusionPsychological stress‐induced mouse model of depression was successfully implemented, with animals exhibiting symptoms of mild or moderate depressive state. This model differs from previous physical stress‐based models, as evidenced by bromodeoxyuridine or orexin‐A staining. Kososan, but not milnacipran, was found to elicit antidepressant‐like effects in this model.
Photoluminescence and Gas Sorption Properties of a New Zinc(II) Coordination Polymer Constructed from Biphenyl‐3,3′,5,5′‐tetracarboxylate Ligand
Authors: Zhou Pingping , Li Xiaohui , Dong Yanli 
Published: January 2015

Abstract A new zinc(II) coordination polymer, namely [Zn3(Hbptc)2(e‐urea)2]n·2n(e‐urea) (1) (H4bptc = biphenyl‐3,3′,5,5′‐tetracarboxylic acid, e‐urea = ethyleneurea), was assemblied by H4bptc and Zn(NO3)2·6H2O under urothermal conditions. Single crystal X‐ray diffraction analysis reveals that compound 1 features a 3D complicated framework with 1D nanotubes, which are occupied by the coordinated and lattice e‐urea molecules. Compound 1 displays strong luminescence emission ability and high thermal stability. In addition, the gas storage properties of N2, H2, and CO2 for the desolvated framework of 1a were also investigated.
Boron Clusters with a Ferrocenylalkynyl Group Bonded to Boron: Synthesis, Characterization, and Electrochemical Trends
Authors: Schäfer Marius , Krummenacher Ivo , Braunschweig Holger , Finze Maik 
Published: January 2015

AbstractThe 12‐vertex closo‐boron clusters [1‐FcC≡C‐closo‐B12H11]2– (1), [12‐FcC≡C‐closo‐1‐CB11H11]– (2), [1‐H2N‐12‐FcC≡C‐closo‐1‐CB11H10]– (3), and [9‐FcC≡C‐closo‐1, 2‐C2B10H11] (5) were synthesized from the corresponding iodinated derivatives and Me3SiC≡CMgBr by a Pd‐catalyzed Kumada‐type cross‐coupling reaction. Anion 3 was converted into the inner salt [1‐Me3N‐12‐FcC≡C‐closo‐1‐CB11H10] (4). The nido‐derivative [5‐FcC≡C‐nido‐7, 8‐C2B9H11]– (6) was obtained from 5 via a deboronation reaction. The tetraethylammonium salts of the anions 2, 3, and 6 as well as compound 5 were characterized by single‐crystal X‐ray diffraction. The redox properties of the ferrocenylalkynyl‐substituted derivatives 1–6 were studied by cyclic voltammetry. An increasing negative charge of the cluster fragment results in a shift of the redox potential of the ferrocene moiety to more negative values. The experimental studies are supported by density functional calculations (DFT).
Resilience in Community: A Social Ecological Development Model for Young Adult Sexual Minority Women
Authors: Zimmerman Lindsey , Darnell Doyanne A. , Rhew Isaac C. , Lee Christine M. , Kaysen Debra 
Published: January 2015

AbstractFamily support and rejection are associated with health outcomes among sexual minority women (SMW). We examined a social ecological development model among young adult SMW, testing whether identity risk factors or outness to family interacted with family rejection to predict community connectedness and collective self‐esteem. Lesbian and bisexual women (N = 843; 57 % bisexual) between the ages of 18–25 (M = 21.4; SD = 2.1) completed baseline and 12‐month online surveys. The sample identified as White (54.2 %), multiple racial backgrounds (16.6 %), African American (9.6 %) and Asian/Asian American (3.1 %); 10.2 % endorsed a Hispanic/Latina ethnicity. Rejection ranged from 18 to 41 % across family relationships. Longitudinal regression indicated that when outness to family increased, SMW in highly rejecting families demonstrated resilience by finding connections and esteem in sexual minority communities to a greater extent than did non‐rejected peers. But, when stigma concerns, concealment motivation, and other identity risk factors increased over the year, high family rejection did not impact community connectedness and SMW reported lower collective self‐esteem. Racial minority SMW reported lower community connectedness, but not lower collective self‐esteem. Families likely buffer or exacerbate societal risks for ill health. Findings highlight the protective role of LGBTQ communities and normative resilience among SMW and their families.
Observation of O2:CO2 exchange ratio for net turbulent fluxes and its application to forest carbon cycles
Authors: Ishidoya Shigeyuki , Murayama Shohei , Kondo Hiroaki , Saigusa Nobuko , Kishimoto‐Mo Ayaka W. , Yamamoto Susumu 
Published: January 2015

AbstractAn average O2:CO2 exchange ratio for net turbulent O2 and CO2 fluxes in a cool temperate deciduous forest in central Japan was obtained based on an aerodynamic method using continuous measurements of atmospheric O2/N2 ratio and CO2 concentration. The average daily mean O2:CO2 exchange ratio was 0.86 during summer, 2013, a value significantly lower than the 1.1 used as a globally averaged terrestrial biospheric O2:CO2 exchange ratio in a CO2 budget analysis. Using the value of 0.86, along with the O2:CO2 exchange ratio of 1.11 for the ecosystem respiration (RE) and 1.00 for the gross primary production (GPP), the net ecosystem production (NEP) measured with an eddy covariance method was separated into GPP and RE using a one‐box canopy O2/CO2 budget model. The estimated average daily‐mean GPP and RE values were consistent, within estimation errors, with those estimated from an empirical function of air temperature; the RE values were also comparable to the soil CO2 efflux observed using an open‐flow soil chamber method. These results suggest that the simultaneous observation of O2 and CO2 concentrations in a forest has potential as a new tool to evaluate the forest CO2 budget.
Legal Recognition of Same-Sex Couples and Family Formation
Authors: Trandafir Mircea 
Published: January 2015

Abstract
It has long been debated how legalizing same-sex marriage would affect (different-sex) family formation. In this article, I use data on OECD member countries for the period 1980–2009 to examine the effects of the legal recognition of same-sex couples (through marriage or an alternative institution) on different-sex marriage, divorce, and extramarital births. Estimates from difference-in-difference models indicate that the introduction of same-sex marriage or of alternative institutions has no negative effects on family formation. These findings are robust to a multitude of specification checks, including the construction of counterfactuals using the synthetic control method. In addition, the country-by-country case studies provide evidence of homogeneity of the estimated effects.
The impact of men's magazines on adolescent boys' objectification and courtship beliefs
Authors: Ward L. Monique , Vandenbosch Laura , Eggermont Steven 
Published: January 2015

ABSTRACTAlthough much attention concerning the potential impact of sexualized media has focused on girls and women, less is known about how this content effects boys' perceptions of women and courtship. Accordingly, the current three‐wave panel study investigated whether exposure to sexualizing magazines predicts adolescent boys' (N = 592) sexually objectifying notions of women and their beliefs about feminine courtship strategies. The results indicated that when boys consumed sexualizing magazines more often, they expressed more gender‐stereotypical beliefs about feminine courtship strategies over time. This association was mediated by boys' objectification of women. The possibility of a reciprocal relation whereby beliefs about courtship strategies predict future consumption of sexualizing magazines was also explored but received no support. Discussion focuses on effects of sexualizing media on boys, and supports future research to build on multidisciplinary knowledge.
Vocal learning, prosody, and basal ganglia: Don't underestimate their complexity
Authors: Ravignani Andrea , Martins Mauricio , Fitch W. Tecumseh 
Published: January 2015

AbstractAckermann et al.'s arguments in the target article need sharpening and rethinking at both mechanistic and evolutionary levels. First, the authors' evolutionary arguments are inconsistent with recent evidence concerning nonhuman animal rhythmic abilities. Second, prosodic intonation conveys much more complex linguistic information than mere emotional expression. Finally, human adults' basal ganglia have a considerably wider role in speech modulation than Ackermann et al. surmise.
Shifted powers in binary recurrence sequences
Authors: BENNETT MICHAEL A. , DAHMEN SANDER R. , MIGNOTTE MAURICE , SIKSEK SAMIR 
Published: January 2015

AbstractLet {uk} be a Lucas sequence. A standard technique for determining the perfect powers in the sequence {uk} combines bounds coming from linear forms in logarithms with local information obtained via Frey curves and modularity. The key to this approach is the fact that the equation uk = xn can be translated into a ternary equation of the form ay2 = bx2n + c (with a, b, c ∈ ℤ) for which Frey curves are available. In this paper we consider shifted powers in Lucas sequences, and consequently equations of the form uk = xn+c which do not typically correspond to ternary equations with rational unknowns. However, they do, under certain hypotheses, lead to ternary equations with unknowns in totally real fields, allowing us to employ Frey curves over those fields instead of Frey curves defined over ℚ. We illustrate this approach by showing that the quaternary Diophantine equation x2n±6xn + 1 = 8y2 has no solutions in positive integers x, y, n with x, n > 1.
A norovirus oyster-related outbreak in a nursing home in France, January 2012
Authors: LOURY P. , LE GUYADER F. S. , LE SAUX J. C. , AMBERT-BALAY K. , PARROT P. , HUBERT B. 
Published: January 2015

SUMMARYThe presence of norovirus in shellfish is a public health concern in Europe. Here, we report the results of an investigation into a norovirus gastroenteritis outbreak following a festive lunch which affected 84 (57%) residents and staff members of a nursing home in January 2012 in France. Individuals who had eaten oysters had a significantly higher risk of developing symptoms in the following 2·5 days than those who had not, the risk increasing with the amount eaten [relative risk 2·2 (1·0–4·6) and 3·3 (1·6–6·6) for 3–4 and 5–12 oysters, respectively]. In healthy individuals during those days, 29 (32%) subsequently became ill, most of whom were staff members performing activities in close contact with residents. Genogroup II noroviruses were detected in faecal samples, in a sample of uneaten oysters and in oysters from the production area. Identifying a norovirus's infectious dose may facilitate the health-related management of contaminated shellfish.
Disrupted autophagy after spinal cord injury is associated with ER stress and neuronal cell death
Authors: Liu S , Sarkar C , Dinizo M , Faden A I , Koh E Y , Lipinski M M , Wu J 
Published: January 2015

AbstractAutophagy is a catabolic mechanism facilitating degradation of cytoplasmic proteins and organelles in a lysosome-dependent manner. Autophagy flux is necessary for normal neuronal homeostasis and its dysfunction contributes to neuronal cell death in several neurodegenerative diseases. Elevated autophagy has been reported after spinal cord injury (SCI); however, its mechanism, cell type specificity and relationship to cell death are unknown. Using a rat model of contusive SCI, we observed accumulation of LC3-II-positive autophagosomes starting at posttrauma day 1. This was accompanied by a pronounced accumulation of autophagy substrate protein p62, indicating that early elevation of autophagy markers reflected disrupted autophagosome degradation. Levels of lysosomal protease cathepsin D and numbers of cathepsin-D-positive lysosomes were also decreased at this time, suggesting that lysosomal damage may contribute to the observed defect in autophagy flux. Normalization of p62 levels started by day 7 after SCI, and was associated with increased cathepsin D levels. At day 1 after SCI, accumulation of autophagosomes was pronounced in ventral horn motor neurons and dorsal column oligodendrocytes and microglia. In motor neurons, disruption of autophagy strongly correlated with evidence of endoplasmic reticulum (ER) stress. As autophagy is thought to protect against ER stress, its disruption after SCI could contribute to ER-stress-induced neuronal apoptosis. Consistently, motor neurons showing disrupted autophagy co-expressed ER-stress-associated initiator caspase 12 and cleaved executioner caspase 3. Together, these findings indicate that SCI causes lysosomal dysfunction that contributes to autophagy disruption and associated ER-stress-induced neuronal apoptosis.
A genome-wide association study of marginal zone lymphoma shows association to the HLA region
Authors: Vijai Joseph , Wang Zhaoming , Berndt Sonja I. , Skibola Christine F. , Slager Susan L. , de Sanjose Silvia , Melbye Mads , Glimelius Bengt , Bracci Paige M. , Conde Lucia , Birmann Brenda M. , Wang Sophia S. , Brooks-Wilson Angela R. , Lan Qing , de Bakker Paul I. W. , Vermeulen Roel C. H. , Portlock Carol , Ansell Stephen M. , Link Brian K. , Riby Jacques , North Kari E. , Gu Jian , Hjalgrim Henrik , Cozen Wendy , Becker Nikolaus , Teras Lauren R. , Spinelli John J. , Turner Jenny , Zhang Yawei , Purdue Mark P. , Giles Graham G. , Kelly Rachel S. , Zeleniuch-Jacquotte Anne , Ennas Maria Grazia , Monnereau Alain , Bertrand Kimberly A. , Albanes Demetrius , Lightfoot Tracy , Yeager Meredith , Chung Charles C. , Burdett Laurie , Hutchinson Amy , Lawrence Charles , Montalvan Rebecca , Liang Liming , Huang Jinyan , Ma Baoshan , Villano Danylo J. , Maria Ann , Corines Marina , Thomas Tinu , Novak Anne J. , Dogan Ahmet , Liebow Mark , Thompson Carrie A. , Witzig Thomas E. , Habermann Thomas M. , Weiner George J. , Smith Martyn T. , Holly Elizabeth A. , Jackson Rebecca D. , Tinker Lesley F. , Ye Yuanqing , Adami Hans-Olov , Smedby Karin E. , De Roos Anneclaire J. , Hartge Patricia , Morton Lindsay M. , Severson Richard K. , Benavente Yolanda , Boffetta Paolo , Brennan Paul , Foretova Lenka , Maynadie Marc , McKay James , Staines Anthony , Diver W. Ryan , Vajdic Claire M. , Armstrong Bruce K. , Kricker Anne , Zheng Tongzhang , Holford Theodore R. , Severi Gianluca , Vineis Paolo , Ferri Giovanni M. , Ricco Rosalia , Miligi Lucia , Clavel Jacqueline , Giovannucci Edward , Kraft Peter , Virtamo Jarmo , Smith Alex , Kane Eleanor , Roman Eve , Chiu Brian C. H. , Fraumeni Joseph F. , Wu Xifeng , Cerhan James R. , Offit Kenneth , Chanock Stephen J. , Rothman Nathaniel , Nieters Alexandra 
Published: January 2015

AbstractMarginal zone lymphoma (MZL) is the third most common subtype of B-cell non-Hodgkin lymphoma. Here we perform a two-stage GWAS of 1,281 MZL cases and 7,127 controls of European ancestry and identify two independent loci near BTNL2 (rs9461741, P=3.95 × 10−15) and HLA-B (rs2922994, P=2.43 × 10−9) in the HLA region significantly associated with MZL risk. This is the first evidence that genetic variation in the major histocompatibility complex influences MZL susceptibility.
Unforeseen high temperature and humidity stability of FeCl3 intercalated few layer graphene
Authors: Wehenkel Dominique Joseph , Bointon Thomas Hardisty , Booth Tim , Bøggild Peter , Craciun Monica Felicia , Russo Saverio 
Published: January 2015

AbstractWe present the first systematic study of the stability of the structure and electrical properties of FeCl3 intercalated few-layer graphene to high levels of humidity and high temperature. Complementary experimental techniques such as electrical transport, high resolution transmission electron microscopy and Raman spectroscopy conclusively demonstrate the unforseen stability of this transparent conductor to a relative humidity up to 100% at room temperature for 25 days, to a temperature up to 150°C in atmosphere and to a temperature as high as 620°C in vacuum, that is more than twice higher than the temperature at which the intercalation is conducted. The stability of FeCl3 intercalated few-layer graphene together with its unique values of low square resistance and high optical transparency, makes this material an attractive transparent conductor in future flexible electronic applications.
New Resources for Audiologists Working With Hispanic Patients: Spanish Translations and Cultural Training
Authors: Reel Leigh Ann , Hicks Candace Bourland , Ortiz Nathan , Rodriguez Amanda 
Published: January 2015

Purpose
Hispanics comprise over 16% of the U.S. population (Humes, Jones, & Ramirez, 2011). Cultural and language differences may negatively affect services audiologists provide to Hispanic patients. The purpose of the current study was to assist monolingual English-speaking audiologists working with Spanish-speaking Hispanic patients by developing appropriate cultural and language instruction materials.

Method
Test descriptions and instructions for hearing and balance tests were developed in English and Spanish. A cultural training module was also created. The first draft of these resources was reviewed by nonaudiologists (bilingual and Spanish monolingual) and audiologists (bilingual and English monolingual). Videos were recorded of the Spanish test instructions read aloud.

Results
Overall, ratings from audiologists and nonaudiologists indicated the translations were easy to understand, and the wording/dialect was appropriate for the region. Audiologists generally reported the information was consistent with what they use clinically, although variability existed in specific wording used. Reviewers rated the cultural training module as easy to understand, relevant to Spanish-speaking patients, and relevant to audiologists. The materials were revised and edited based on feedback from reviewers.

Conclusions

The current study developed materials for monolingual English-speaking audiologists working with Spanish-speaking Hispanic patients. The final translations are provided as online
supplemental materials
.

Supplemental Material

https://doi.org/10.23641/asha.6170180
Reliability and Validity of the Computerized Revised Token Test: Comparison of Reading and Listening Versions in Persons With and Without Aphasia
Authors: McNeil Malcolm R. , Pratt Sheila R. , Szuminsky Neil , Sung Jee Eun , Fossett Tepanta R. D. , Fassbinder Wiltrud , Lim Kyoung Yuel 
Published: January 2015

Purpose
This study assessed the reliability and validity of intermodality associations and differences in persons with aphasia (PWA) and healthy controls (HC) on a computerized listening and 3 reading versions of the Revised Token Test (RTT; McNeil & Prescott, 1978).

Method
Thirty PWA and 30 HC completed the test versions, including a complete replication. Reading versions varied according to stimulus presentation method: (a) full-sentence presentation, (b) self-paced word-by-word full-sentence construction, and (c) self-paced word-by-word presentation with each word removed with the onset of the next word. Participants also received tests of aphasia and reading severity.

Results

The listening version produced higher overall mean scores than each of the reading versions. Differences were small and within 1 standard error of measurement of each version. Overall score test–retest reliability among versions for PWA ranged from
r
= .89 to
r
= .97. Correlations between the listening and reading versions ranged from
r
= .79 to
r
= .85. All versions correlated highly with aphasia and reading severity. Correlations were generally low for the HC due to restricted variability. Factor analysis yielded a 2-factor solution for PWA and a single-factor for HC.

Conclusions
Intermodality differences were small, and all 4 versions were reliable, concurrently valid, and sensitive to similar linguistic processing difficulties in PWA.
In vivo, Argonaute-bound microRNAs exist predominantly in a reservoir of low molecular weight complexes not associated with mRNA
Authors: La Rocca Gaspare , Olejniczak Scott H. , González Alvaro J. , Briskin Daniel , Vidigal Joana A. , Spraggon Lee , DeMatteo Raymond G. , Radler Megan R. , Lindsten Tullia , Ventura Andrea , Tuschl Thomas , Leslie Christina S. , Thompson Craig B. 
Published: January 2015

Significance
MicroRNAs limit gene expression by recruiting a large protein complex known as the RNA-induced silencing complex (RISC) to target mRNAs. While attempting to understand physiological regulation of RISC assembly, we found that most healthy adult tissues retain a reserve of microRNAs not stably associated with target mRNA. Recruitment of microRNAs to large mRNA-containing complexes was accompanied by an increase in their ability to repress targets and was regulated in part by phosphoinositide-3 kinase–RAC-alpha serine/threonine-protein kinase–mechanistic target of rapamycin pathway-dependent enhancement of the glycine-tryptophan protein of 182 kDa protein expression. Data presented here suggest that in vivo, many expressed microRNAs exist in an inactive reserve, allowing resting cells to use microRNAs to dynamically regulate the translation of target mRNAs in their environment.
Examining the Relationship between the Use of Supermarkets and Over‐nutrition in Indonesia
Authors: Umberger Wendy J. , He Xiaobo , Minot Nicholas , Toiba Hery 
Published: January 2015

AbstractThis study examines the relationship between the use of modern food retailers and health outcomes using data from a survey of 1,180 urban households in Indonesia. The dependent variables include adult and child body‐mass index and the share of individuals overweight and obese. After controlling for individual and household characteristics and using standard and Lewbel instrumental variable approaches to control for unobservable characteristics, we do not find a statistically significant relationship between use of supermarkets and adult nutrition measures. On the other hand, there is mixed evidence for a negative effect of supermarkets on child nutrition, particularly for those in high‐income households.