bluuebunny/crossref_metadata_2025_split huggingface dataset:
Relationship between family socioeconomic status and toddlers’ social-emotional development : the mediation effects of home rearing environment
Authors: Xu Yuying , Meng Yanfei , Dong Xueli , Wang Suqing , Yu liping 
Published: August 2024

Abstract

Background
The development of children's social emotional ability is crucial for their future success. Increasing evidence suggests that families with low socioeconomic status negatively influence the development of children's social emotions, although the mechanisms underlying this association remain unclear. The home rearing environment is the primary setting that toddlers are exposed to in their early years, significantly impacting their emotional development. This environment may be affected by the family’s economic situation.
Methods
A total of 370 healthy toddlers aged 12 to 36 months were recruited through the Maternal and Child Health Hospital in Wuhan. Socio-economic status was assessed using parents' education level and family income. The home environment was measured using the Child Home Nurture Environment Scales. Toddlers’ social-emotional was measured using the 12 to 36 months toddler social emotional questionnaire.
Results
The mean age of the toddlers was 27.71 ± 7.76 months. Family socioeconomic status, home rearing environment, and social-emotion development were significantly correlated (P < 0.05). Family socioeconomic status did not have a direct predictive effect on toddlers' social-emotional development. However, the family nurturing environment played a significant mediating role between family socioeconomic status and toddlers’ social-emotional outcomes, with a 95% confidence interval of 0.467–0.643.
Conclusions
Socioeconomic status may affect the social-emotional development of young children through the family upbringing environment. Health care workers should provide training on parenting knowledge to foster a positive family upbringing environment and mitigate the negative impact of low socioeconomic status on young children's emotional development.
Association of Dietary and Lifestyle Inflammation Score with sleep quality and mental health in hemodialysis patients: A multicenter cross-sectional study
Authors: Damaneh Mohadeseh Soleimani , Behbahani Hossein Bavi , Alipour Meysam , Javid Ahmad Zare , Keramatzadeh Sara , Shokri Shiva , Tofighzadeh Pardis , Fayazfar Fatemeh , Dehkordi Haleh Soltaniyan , Ghadimi Elahe , Esfandabad Siavash Babajafari , Shayanpour Shokouh 
Published: August 2024

Abstract

Background
Poor sleep quality and mental disorders are common issues among patients undergoing dialysis. Diet and lifestyle may be associated with sleep hygiene and mental health. The current study aimed to evaluate the association between the Dietary and Lifestyle Inflammation Score (DLIS) and mental health, and sleep quality among Iranian hemodialysis patients.
Methods
This multicenter cross-sectional study was conducted on 423 patients undergoing hemodialysis in eight centers in three cities. The DLIS was calculated using information from a validated 168-item semi-quantitative food frequency questionnaire. Mental health was evaluated using the 21-item depression, anxiety, and stress scale (DASS-21) and the Pittsburgh Sleep Quality Index (PSQI) was used to assess sleep quality. Other assessments included physical activity levels, biochemical parameters, and dialysis data of patients. Statistical analyses using SPSS software were conducted to identify associations.
Results
The mean ± standard deviation of the age and BMI were 52.84 ± 14.63 years and 24.8 ± 5.11 kg/m2, respectively. 58.9% of participants were men. After controlling for potential confounders, participants in the top quartile of DLIS had greater odds of having poor sleep quality (OR: 3.18; 95% CI: 1.71–5.90), depression (OR: 1.94; 95% CI: 1.06–3.54), anxiety (OR: 2.82; 95% CI: 1.51–5.27), and stress (OR: 2.15; 95% CI: 1.14–4.03) compared with those in the bottom quartile.
Conclusion
Our findings showed that higher dietary and lifestyle inflammatory potential, characterized by higher DLIS, was positively associated with psychological disorders and poor sleep quality.
Exploring the trainee experience during a combined technical and non-technical skills obstetric training session on a simulated labour ward: A rapid ethnographic study
Authors: Siddharth Aditi , Nadia Muspratt Tucker , Nambiar Divya , Houlden Ruth , Aitken Debbie , Higham Helen 
Published: August 2024

Abstract

Background:
Obstetric training requires competence in both technical and non-technical skills (TS and NTS). Traditionally the acquisition of these skills is dependent on experience more than formal teaching. Simulation training can be an opportunity to bridge this gap in a safe environment. This study explores the impact of merging TS and NTS simulation into a single session of an obstetric on call on a simulated labour ward.
Methods:
All obsetric specialist trainees year 1 and 2 (ST1-2) from the Thames Valley Deanery (n = 14) participated in a 40 minute simulated labour ward oncall,managing patients on the labour and antenatal wards and maternity assessment unit. The trainees were divided into two groups, each group participated in the simulation followed by a focus group discussion. This study used rapid ethnography with in-situ observation, audio recordings, field notes and focus group interviews. Data analysis used Kopta’s 3 phase theorical framework of technical skill learning- cognitive, integrative and autonomous.
Results:
Trainees learnt TS in all three Kopta’s phases during this simulation. The trainee’s familiarity with the TS determined the phase of learning they achieved. For less familiar tasks, trainees were in the cognitive phase. The integrative phase was seen when the TS was partially familiar and required them to perform it in conjunction with the appropriate NTS. There was autonomous TS and NTS integration with tasks they were skilled in.
Conclusion:
Integrating TS and NTS simulation optimised the learning opportunities within one training session. This model is adaptable to various skill levels and specialities, without increasing trainee, faculty, or resource burden. Further exploration can broaden applicability of this approach across other specialities.
Assessment of symptom burden and quality of life in patients with primary brain tumors receiving palliative care in a tertiary cancer care centre
Authors: Padhi Pratyasa , Gupta Nishkarsh , Bharati Sachidanand Jee , Garg Rakesh , Mishra Seema , Bhatnagar Sushma , KP Haresh , Kumar Vinod 
Published: August 2024

Abstract

Background
Primary brain tumor patients present with a unique trajectory of illness, with an uncertain prognosis, a rapid decline in physical functioning and a significant worsening of quality of life.
Methods
The EORTC QLQ C30 & EORTC BN 20 questionnaires were used to assess quality of life and symptom burden in patients with primary brain tumors. The scores were analysed using SPSS statistical software.
Results
One hundred patients—61 males and 39 females—with radiological or histo-pathological diagnoses of primary brain tumors were included. Seizures (38%) were the most common presenting symptom (38%), followed by headache (18%), loss of consciousness (13%), focal neurological deficit (9%) and blurring of vision (8%). The mean quality of life at baseline was 78.29, with a standard deviation of 9.67 on a scale of 0 to 100, and the brain tumor-specific symptom burden score was 46.9, with a standard deviation of 17.95 on a scale of 0 to 100. There was a significant difference in the global health status score between the first visit and third visit, i.e., at three months (p value = 0.03).
Conclusion
Primary brain tumors are often aggressive and deemed incurable. Unaddressed symptoms such as fatigue and insomnia, future uncertainties and decreased social functioning are widely prevalent in such patients. The integration of palliative care in the treatment course is important to ensure good quality of life in such patients.
Navigating Uncertainty in Patient Care: A CLoser Look at Emergency Medicine Residents in Brazil
Authors: Boemeke Gabriela , Barbosa Larissa , Quintanilha Luiz , Avena Kátia , Andrade Bruno 
Published: August 2024

Abstract

Background. In emergency situations, the inexperience and complexity of cases can lead to uncertainty and stress among doctors, affecting their decision-making and negatively impacting patients and the healthcare system. Despite the importance of this topic, studies on uncertainty among Emergency Medicine residents are limited. Aim. Our study aims to investigate decision-making uncertainty among Emergency Medicine residents (EMR), identifying the most affected dimensions and assessing the impact of sociodemographic and academic profiles.
Methods. This is a cross-sectional study that includes EMR in Brazil, with no restrictions on the year of specialization. Data was collected using the snowball method through an anonymous, structured electronic form distributed via virtual groups and e-mail. Measurements included sociodemographic and academic questions, as well as the application of the Physicians Reactions to Uncertainty (PRU) questionnaire, which quantifies physicians' uncertainty in decision-making.
Results. A total of 124 residents participated in the study, with the majority being women (52.4%), over 26 years old (77.4%), in their first year of residency (49.2%), and without previous graduation on other academic fields (94.7%) or prior medical specializations and residencies (91.9%). The year of residency significantly influenced the perception of uncertainty, with first-year residents showing less ability to handle it (p=0.003). Participants with prior graduation in health-related fields aside from medicine and those with prior specializations demonstrated less intense reactions to uncertainty (p=0.041 and p=0.036, respectively). First-year residents experienced greater stress related to uncertainty (p<0.001), while those with previous graduation other than medicine were less reluctant to share their mistakes (p=0.003).
Conclusion. Experience, in terms of years of residency or prior graduations, significantly impacts physicians' reactions, reducing perceived uncertainty and mitigating its emotional and cognitive impact. This can directly influence clinical decisions, behaviors, and overall well-being.
Integrated Geological Analysis of the AI Well, Niger Delta Basin: Insights into Reservoir Characterization and Hydrocarbon Potential
Authors: Maju-Oyovwikowhe Efetobore Gladys , Aigbadon Godwin , Egharevba Aisosa 
Published: August 2024

Abstract

This study presents a comprehensive investigation of the AI well within the Agbada Formation, focusing on its depositional environment, reservoir characteristics, and dominant mineralogical composition. One hundred rock samples were collected at various depths ranging from 6000 ft to 10120 ft and subjected to detailed petrographic, geochemical, and sedimentological analyses. Petrographic thin section analysis, X-ray Diffraction (XRD), and X-ray Fluorescence (XRF) were performed on five selected samples to determine their mineral phases and geochemical compositions. Sedimentological analysis of the remaining samples included assessments of grain size, sorting, and lithofacies. The petrographic analysis revealed quartz as the predominant mineral, constituting 27.2–28.8% of the reservoir components, along with plagioclase (3.8–2.5%) and clay minerals (57.2–52.8%). XRD results supported these findings, showing quartz content ranging from 35–51%. XRF analysis indicated that SiO2 is the most abundant oxide (63.264–36.662%), followed by Fe2O3 (19.718–10.519%), and Al2O3 (16.147–10.462%). Sedimentological results revealed an almost equal sand-clay ratio, suggesting a paralic depositional environment within the Agbada Formation of the Niger Delta. The integration of geochemical, petrographic, and sedimentological data provides detailed insights into the reservoir characteristics and mineral composition, highlighting factors that can influence reservoir performance. These findings contribute to a better understanding of the depositional environments and diagenetic processes within the Niger Delta Basin, offering valuable implications for hydrocarbon exploration and reservoir management.
Highly efficient synthesis of the chiral ACE inhibitor intermediate (R)-2-hydroxy-4-phenylbutyrate ethyl ester via engineered bi-enzyme cascade systems
Authors: dai yanmei , Wang Jinmei , Tao Zijuan , Luo Liangli , Huang Changshun , Liu Bo , Tang Lan , Ou Zhimin 
Published: August 2024

Abstract

(R)-2-Hydroxy-4-phenylbutyric acid ethyl ester ((R)-HPBE) represents a crucial chiral intermediate in the synthesis of angiotensin-converting enzyme (ACE) inhibitors. Its preparation entails an asymmetrical reduction of ethyl 2-oxo-4-phenylbutyrate (OPBE) with high selectivity by carbonyl reductase, a process that necessitates the regeneration of the cofactor as a pivotal aspect. The carbonyl reductase gene (CpCR) in Candida parapsilosis ATCC 7330 was successfully cloned in our laboratory. A series of recombinant engineering bacteria were constructed based on the cloned CpCR gene. These included E. coli BL21-pETDuet-1-CpCR, E. coli BL21-pET28a-CpCR and E. coli BL21-pACYCDuet-1-CpCR, which expressed the CpCR monoenzyme. To address the issue of cofactor regeneration, glucose dehydrogenase (GDH) was incorporated into the reaction system to construct a bi-enzyme cascade system, which included three co-expression recombinant engineering bacteria (E. coli BL21-pETDuet-1-CpCR/pACYCDuet-1-GDH, The following recombinant engineering bacteria were constructed: E. coli BL21-pETDuet-1-CpCR-GDH and BL21-pETDuet-1-GDH-CpCR, as well as E. coli BL21-pETDuet-1-CpCR-L-GDH and E. coli BL21-pETDuet-1-GDH-L-CpCR, which were created through fusion expression. Subsequent studies demonstrated that the fusion-expressed bi-enzyme cascade recombinant engineering bacteria E. coli BL21-pETDuet-1-GDH-L-CpCR exhibited superior carbonyl reductase activity compared to CpCR single-enzyme recombinant engineering bacteria and bi-enzyme co-expression recombinant engineering bacteria. This was evidenced by a 3-fold increase in substrate processing capacity at a reaction temperature of 30 ℃and a reaction time of 24 h. With a substrate loading of 30 mM OPBE, (R)-HPBE was achieved in 92.1% conversion with an enantiomeric excess value of 99.9%.
Effect of adjuvant treatments on the diameter of recipient vessels for free flap breast reconstruction: A computed tomographic angiography-assisted analysis
Authors: Choi Jong Yun , Lee Junhyeok , Jun Daiwon , Rhu Jiyoung , Paik Pill Sun , Lee Jung Ho 
Published: August 2024

Abstract

The quality of the recipient vessel is critical for good outcomes after microsurgical breast reconstruction, and damage to the recipient vessels should be minimized. Radiation therapy (RTx) and chemotherapy (CTx) are widely used as adjuvant treatments for breast cancer. They may result in changes in recipient vessels for microsurgical breast reconstruction. Therefore, in this study, we evaluated the changes in recipient vessels for breast reconstruction after adjuvant treatment for breast cancers. Overall, 167 patients with unilateral breast cancer who underwent surgical resection between 2017 and 2021 were selected. Notably, 33 of these patients received only mastectomy without adjuvant treatment (Group A), 44 received only adjuvant RTx (Group B), 43 received only adjuvant CTx (Group C), 47 patients received both adjuvant CTx and RTx (Group D). Using preoperative and postoperative computed tomography (CT) angiography, the vessel diameters of the thoracodorsal artery (TDA) and the internal mammary artery (IMA) on the affected and unaffected sides were measured, and differences in vessel diameters between the two sides and characteristics of each group were analyzed. The diameter of affected vessels (TDA and IMA) significantly decreased in groups B and D compared with the changes in vessel diameters on the unaffected side (p < 0.001). However, there was no significant difference in the diameter of vessels in groups A and C (Group A: p = 0.644, Group B: p = 0.367). Therefore, the diameter of recipient vessels for microsurgical breast reconstruction significantly decreased when RTx was performed postoperatively. Thus, plastic surgeons conducting delayed breast reconstruction must thoroughly understand the changes in recipient vessels associated with adjuvant treatment. Consequently, the preoperative consideration of these possibilities enables plastic surgeons to provide patients with accurate information about the risks associated with surgery, ensuring that informed decisions are made.
The Power of Fame: Evaluating Celebrity Influence on Brand Attention, Emotion, and Memory
Authors: Michael Noela , Zoega Thomas , Michael Ian 
Published: August 2024

Abstract

This study focuses on the growing trend of celebrities being used as influencers in marketing, with firms investing substantially in celebrity endorsements. The study examines the effectiveness of celebrity influencers in destination marketing, comparing their influence with that of non-celebrity influencers. Neuroscience tools and methods were used to understand how cognitive and emotional factors impact consumer decisions and their likelihood to travel. The results show that employing a celebrity does not always increase audience engagement and attention toward the destination. The average person perceives the celebrity as a whole rather than focusing on one specific feature. Moreover, there were no significant differences in motivating levels or emotional responses between advertisements with influencers and those with unknown individuals. Celebrity influencers often do not contribute much to the cognitive load of viewers, although there are certain situations where they may slightly increase mental effort. The results suggest that influencer marketing can attract attention but should not overshadow the brand.
Evolving a safe blasting regime near an earthen dam through geophysical assessment
Authors: Vajre R. , Iyer V. , Sharma P. , Raina A. K. 
Published: August 2024

Abstract

Earthen dams are vulnerable to damage through nearby construction, particularly vibrations generated by blasting used for the excavation of hard rock. As such, there are restrictions by dam authorities that prohibit excavation beyond a certain depth near a dam. A similar case was observed near an earthen dam in India, where blasting was proposed for construction of a new railway line. To restrict vibrations due to blasting, it was imperative to develop a methodology and define the maximum allowable limits of vibrations near the dam toe. This meant defining the attenuation characteristics of the vibrations and assessing the natural frequency of the dam. A comprehensive geophysical investigation of the dam was conducted, which revealed a natural frequency of 2 to 4 Hz along with subsurface s-wave velocities in the range of 166 to 981 m/s. An empirical method was used to predict natural frequencies ranging from 1.82 to 4.59 Hz, thus matching those measured via geophysical methods. Finally, a vibration criterion based on the frequency and type of structure was used to obtain a threshold vibration level of 5 mm/s. Few blasts were conducted and the actual measurements of the vibrations at approximately 480 m proved that the vibration levels at the dam toe were less than 2 mm/s, thereby validating the predictions of vibrations.
Comparison of the Effects of Kinesio Taping and Rigid Taping in Knee Osteoarthritis
Authors: Saad Muhammad , Jamil Muhammad Ammad , Khan Lal Gul 
Published: August 2024

Abstract

Background:According to different researches kinesio and rigid taping both found to have a positive effect on the treatment for knee osteoarthritis, whereas kind of taping which is more 8 effective still require investigations.
Objective:To compare the effect of kinesio taping and rigid taping on the pain, range of motion and limited functioning in knee osteoarthritis.
Methodology: A randomize control trails was conducted at ATTA MEMORIAL HOSPITAL from October 2022 to May 2023. 36 Patients aged 40-60 years with grade 1-3 osteoarthritis suffering from 6 months were included in this study. These 36 Patients were randomly divided into two groups, Group A with 18 patients received the Kinesio taping while group B with 18 patients received rigid taping, while conventional therapy was given to both groups. Patients were also guided about postural care. Analysis was done by SPSS 22.
Results: Analysis of data within group by Freidman test shows significant improvement in pain, range of knee flexion and extension, and functional activities measured by WOMAC index (p-value is <0.001). However, Mann Whitney U test comparison between the two groups showed no statistically significant difference, indicating the similar effectiveness of all the measured parameters in knee osteoarthritis patients.
Conclusion: The study concludes that both interventions, kinesio and rigid taping, along with conventional treatment, are equally effective for reducing pain , increasing range of motion and improving functional limitations for knee osteoarthritis patients.
Registration: The trails were registered on classic.clinicaltrails.gov with NCT number: NCT05946434.
Hydrological Connectivity Induces Changes in Macrobenthos Functional Feeding Groups in a Typical Tidal Creek System of the Yellow River Delta
Authors: Fu Qinglu , Chen Li , Sun Debin , Wang Jiao , Chen Jing , Li Baoquan , Chen Linlin 
Published: August 2024

Abstract

Hydrological connectivity in tidal creek systems is a fundamental element of coastal wetland ecosystems, influencing the interactions among various key ecological factors within the wetlands. Understanding the mechanisms by which hydrological connectivity affects the functional feeding groups (FFGs) of macrobenthos is crucial for the restoration and maintenance of wetland ecosystems and biodiversity. This study focuses on a typical tidal creek system in the Yellow River Delta, where we investigated macrobenthos, environmental factors, and metal elements across different seasons in tidal creek areas. We employed multi-element fingerprint analysis, non-metric multidimensional scaling (NMDS) analysis, hierarchical cluster analysis (HCA), biological co-occurrence network analysis, and redundancy analysis (RDA) to explore the impact of hydrological connectivity on the ecological functions of tidal creek systems and the structure of macrobenthos FFGs. The results indicate that tidal creeks with greater differences in hydrological connectivity exhibit lower chemical connectivity. Scrapers had the highest abundance proportion in the tidal creek system, accounting for 40.9%. Gathering-collectors were identified as the key feeding functional group for maintaining the stability of biological communities. Areas with high hydrological connectivity showed strong synergistic effects and stability within the macrobenthos communities. The study further demonstrated that hydrological connectivity is a factor influencing the complexity of biological co-occurrence networks in typical tidal creeks. Sediment organic carbon, silicate, ammonia nitrogen, and metal element contents were identified as key factors affecting the structure of macrobenthos FFGs. Ecological function results suggest that high hydrological connectivity characteristics contribute to maintaining the productivity and stability of tidal creek systems.