bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Hellenic Orff-Schulwerk Association (ESMA): Historical Review, Evolution and Prospects
Authors: Agalianou Olympia , Alexiadi Katerina 
Published: July 2024

This article provides a historical review of the Hellenic Orff-Schulwerk Association (ESMA) from its founding until today. Polyxeni Matéy introduced the Orff approach in Greece during the third decade of the 20th century and her students have played an important role in expanding the Orff approach in Greece. After a brief reference to the history of the two first decades of the successful function of ESMA, the article focuses on the associations’ goals and perspectives in the third decade of its existence. In the current situation of Greece and its socioeconomic conditions, ESMA places great importance on linking its activity to fields such as inclusive education and social work providing scientific support to teachers that work in these areas.
Influence of NaBH4 on the sensitivity of As3+ and As5+sensor using gold modified boron doped diamond electrodes
Authors: Yuliandari Pratiwi , Lestarini Dian Tri , Khalil Munawar , Einaga Yasuaki , Jiwanti Prastika Krisma 
Published: July 2024

Background: Arsenic is known as one of the carcinogenic metalloids and can cause various health issues when ingested or inhaled over prolonged periods of time. Methods: In this work, boron-doped diamond (BDD) electrode was altered with gold particles (Au) arranged by seeding continued with electrodeposition of HAuCl4 solutions at the electrode surface, will be used as electrode to detect As3+ and As5+ in lake water. The deposited gold particles on BDD surface were studied with scanning electron microscopy-energy dispersive spectroscopy (SEM-EDS) and X-ray photoelectron spectroscopy (XPS). Detections of As3+, As5+, and mixture solutions of As3+ and As5+, carried out with anodic stripping voltammetry (ASV). Findings: The, pre-treatment using NaBH4 carried out for reduction from As5+ to As3+, indicate an improvement at the sensitivity of As3+ and As5+ detection with a good linear responses for each solution in range concentrations of 0.02-0.2 ppm for As3+ and As5+, with R2=0.9759 and R2= 0.9876, respectively. Conclusion: Furthermore, limit of detections of 0.0335 ppm and 0.0239 ppm can be attained for As3+ and As5+ displayed high linearity, revealing that detection of each species of As3+ and As5+ can be conducted in mixture of As3+ and As5+.
Pengaruh Beban Pajak Profitabilitas Dan Leverage Terhadap Keputusan Transfer Pricing Dengan Mekanisme Bonus Sebagai Variabel Intervening
Authors: Baiti Nurul , Sastrodiharjo Istianingsih , Rely Gilbert 
Published: July 2024

Tujuan : Tujuan dari penelitian ini adalah untuk mengkaji pengaruh tiga variabel eksogen (Tax Expute, Profitability, Leverage), satu variabel endogen (Transfer Pricing), dan satu variabel mediasi (Bonus Mechanism) pada perusahaan pertambangan yang diperdagangkan secara publik di Bursa Efek Indonesia (BEI) dalam jangka waktu 2018-2022.

Metodologi : Metodologi penelitian yang diterapkan dalam penelitian ini melibatkan pemanfaatan Analisis Jalur melalui perangkat lunak SPSS versi 25.0.

Hasil penelitian : Biaya Pajak tidak mempengaruhi keputusan terkait dengan transfer pricing dan mekanisme bonus, sedangkan Profitabilitas menunjukkan pengaruh yang menguntungkan pada Mekanisme Bonus tetapi tidak mempengaruhi transfer pricing. Selain itu, Leverage menunjukkan korelasi positif dengan Mekanisme Bonus tetapi tidak mempengaruhi harga transfer. Selain itu, Mekanisme Bonus ditemukan tidak berpengaruh pada transfer pricing. Disimpulkan bahwa mekanisme bonus tidak secara signifikan mempengaruhi harga transfer dalam perusahaan manufaktur.
Temuan ini mengusulkan bahwa dampak mekanisme bonus dapat bervariasi berdasarkan konteks spesifik dan atribut perusahaan.
الإثبات الجنائي عن طريق اللغة - بحث في دور البصمة الصوتية في ضوء اللسانيات الجنائية -
Authors: Firane Nadjwa 
Published: July 2024

تطورت العلوم اللسانية المختلفة و ازدهرت دراساتها ، ففتحت آفاقا جديدة في البحوث العلمية المعاصرة لاسيما و أنّها اقترنت بغيرها من العلوم و الفروع البحثية مؤسسة لعلوم بينية جديدة كاللسانيات الحاسوبية ، اللسانيات العصبية، اللسانيات العرفانية، اللسانيات الاقتصادية....، كما بحثت اللسانيات في كثير من القضايا القانونية من خلال تحليل لغة القانون ، بله تعمّقت أكثر في الجرائم و الجنايات لتؤسّس هذه الدراسات لعلم بيني جديد سمي باللسانيات القانونية أو اللسانيات الجنائية، و الذي جعل من اللغة أداة للوصول إلى الجناة و المتهمين.
يسعى البحث للتعريف بهذا العلم وبمصطلحاته وأدواته الإجرائية المستخدمة في التحقيق الجنائي القائم على اللغة، كما يركّز على علم بيني آخر يدعى الصوتيات الجنائية الذي يضطلع بمهمة بيان كيف تصير البصمة اللسانية والبصمة الصوتية بالتحديد عاملا فاصلا في الكشف عن خيوط الجريمة و ملابساتها و منفذيها، من خلال توظيف أجهزة التحليل الصوتي و الحواسب في هذا المجال.
Effect of intensity training block on anxiety state and performance in competitive swimmers
Authors: Aouani Hajer , Amara Sofiene , Sahli Faten , Barbosa Tiago M. , Souissi Nizar , Tillaar Roland van den 
Published: July 2024

Background
An increase in training intensity could create changes in psychological and physiological variables in competitive athletes. For this reason, it is very relevant to know how an intensive training block could influence psychological variables in competitive swimmers. This study examined the effect of an intensive training block (HIT) for 2 weeks on the anxiety state and swimming performance compared to standard aerobic training.

Methods
Twenty-two male competition swimmers were randomly assigned to two groups: HIT group (n = 11; age = 16.5 ± 0.29 years) and control group following the standard training program (n = 11; age = 16.1 ± 0.33 years). Psychological status variables (cognitive anxiety, somatic anxiety and self-confidence) and swimming performance (100-m front crawl) were measured pre-and post-test.

Results
A significant effect of time was found for all psychological variables and swimming performance (F ≥ 17.6; p < 0.001; d ≥ 0.97). Furthermore, a significant group × time interaction effect was found in cognitive (F = 14.9; p < 0.001; d = 0.62) and somatic anxiety (F = 5.37; p = 0.031; d = 0.55) were found. Only a significant group effect was found in somatic anxiety (F = 27.1; p < 0.001; d = 1.2). Post hoc comparison revealed that both groups increased their cognitive anxiety and swimming performance, and decreased their self-confidence from pre to post test. However, cognitive anxiety increase significantly more in the HIT group compared to the control group. Furthermore, only the HIT training group significantly increased somatic anxiety over time, while somatic anxiety did not change significantly over time in the control group.

Conclusion
Our findings indicated that a sudden increase in training intensity increased state anxiety more than standard training, but both conditions similarly enhanced swimming performance. Although the current level of psychological state is not affecting swimming performance negatively over this period, it should be regularly monitored by psychologists as it over a longer training period perhaps could have a negative influence on swimming performance.
Relationships between diurnal changes in blood pressure and catecholamines among Filipino‐American and European‐American women
Authors: Van Berge‐Landry Helene , James Gary D. , Brown Daniel E. 
Published: April 2013

ObjectivesStudies show that diurnal blood pressure (BP) sensitivity to epinephrine (EPI) in African‐American women is significantly greater than that of European‐American (EA) women. Few if any studies have examined diurnal catecholamine‐BP relationships in women of other ethnic groups. The purpose of this study was to compare the effects of diurnal changes in EPI and norepinephrine (NE) on the diurnal changes in BP between Filipino‐American (FA) and EA women.MethodsThe subjects included 31 FA and 27 EA nurses and nurses aides and eight FA and 19 EA hotel workers from Hawaii who wore an ambulatory BP monitor and collected timed urine specimens (4 h at work, approx.4 h at home and approx. 8 h overnight) for assay of EPI and NE. Proportional changes in systolic and diastolic BP from sleep to work and sleep to home were examined using ANCOVA models including fixed effect‐covariate interactions, with ethnicity as a fixed factor, and BMI and the appropriate proportional change in EPI or NE as covariates.ResultsThe results show that there was no association between changes in EPI and BP, either overall or by ethnic group; however, overall changes in diastolic BP from sleep to work tended to be smaller among the FAs (P < 0.06). There was also an interactive effect of NE and ethnic group on diastolic BP such that among FAs, as diastolic BP increased, the corresponding NE change decreased (P < 0.039).ConclusionThe relationships between diurnal BP and catecholamine variations differ by ethnicity. Further research is needed to better understand the mechanisms behind the differences and to evaluate whether this vascular tonic relationship has been the focus of natural selective processes. Am. J. Hum. Biol. 25:431–433, 2013. © 2013 Wiley Periodicals, Inc.
Characterization of the infant BMI peak: Sex differences, birth year cohort effects, association with concurrent adiposity, and heritability
Authors: Johnson William , Choh Audrey C. , Lee Miryoung , Towne Bradford , Czerwinski Stefan A. , Demerath Ellen W. 
Published: April 2013

ObjectivesTo characterize an early trait in the BMI‐for‐age curve, the infant BMI peak.MethodsBMI‐for‐age curves were produced for 747 non‐Hispanic, white Fels Longitudinal Study participants, from which individual age (AgePeak) and BMI (BMIPeak) at maximum infant BMI were estimated. Multivariable general linear regression was used to examine the effects of sex and birth year cohort (1929–1950, 1951–1970, and 1971–2010) on AgePeak and BMIPeak, with associations between BMIPeak and concurrent sum of four skinfold thicknesses assessed in a subsample (N = 155). Heritability (h2) of AgePeak and BMIPeak was estimated using maximum‐likelihood variance components analysis.ResultsAgePeak occurred at 9 months of age in both sexes, but BMIPeak was 0.4 kg/m2 higher for boys than for girls (P‐value < 0.001). Infants born between 1971 and 2010 experienced a 1.5 month earlier AgePeak and a 0.35 kg/m2 lower BMIPeak than infants born between 1929 and 1950 (P‐values < 0.001). Skinfold thickness explained 37% of the variance in BMIPeak in boys and 20% of the variance in girls (p‐values < 0.001). AgePeak and BMIPeak were significantly heritable (h2 = 0.54 and 0.75, respectively).ConclusionsBoth AgePeak and BMIPeak decreased over successive birth year cohorts in the Fels Longitudinal Study. Despite a positive association of BMIPeak with concurrent adiposity, AgePeak appears to occur later than does the well‐documented peak in infant fat mass and BMIPeak does not capture known sex differences in infant adiposity. Strong heritability of these infant BMI traits suggests investigation of genetic control, and validation of their relationship to body composition is greatly needed. Am. J. Hum. Biol. 25:378–388, 2013. © 2013 Wiley Periodicals, Inc.
Relationships between biomarkers of inflammation, ovarian steroids, and age at menarche in a rural polish sample
Authors: Clancy Kathryn B.H. , Klein Laura D. , Ziomkiewicz Anna , Nenko Ilona , Jasienska Grazyna , Bribiescas Richard G. 
Published: April 2013

ObjectivesTo test the hypothesis that life history trade‐offs between maintenance and reproductive effort would be evident through inverse associations between levels of a biomarker of inflammation [C‐reactive protein (CRP)], and ovarian hormones. Associations between CRP and age at menarche were also explored.MethodsUrinary CRP, salivary progesterone, and estradiol were measured over one menstrual cycle from rural Polish women (n = 25), representing a natural fertility sample. Age of menarche was assessed through interview recall methods. We used minimum second‐order Akaike Information Criteria as a means of multiple regression model selection, and repeated measures ANOVA to test cycle‐dependent hypotheses.ResultsComparisons of individuals in high and low CRP tertiles revealed that those with high CRP had significantly lower progesterone (luteal P = 0.03, mid luteal P = 0.007) but not estradiol (follicular P = 0.21, luteal P = 0.15) concentrations through the menstrual cycle. However, when the age at menarche was included in the analysis, both age at menarche and urinary CRP were negatively associated with estradiol (R2 = 0.44, P = 0.0007). Age at menarche and estradiol were the strongest negative predictors of CRP (R2 = 0.52, P = 0.0001).ConclusionsInflammation itself may suppress ovarian function, or indicate immune challenges that lead to ovarian suppression. The timing of menarche may also influence adult inflammatory sensitivity and ovarian hormone concentrations. This lends support to existing models of trade‐offs between maintenance and reproduction in women. Am. J. Hum. Biol. 25:389–398, 2013. © 2013 Wiley Periodicals, Inc.
Ambulatory blood pressure and blood lipids in a multiethnic sample of healthy adults
Authors: James Gary D. , Van Berge‐Landry Helene M. , Morrison Lynn A. , Reza Angela M. , Nicolaisen Nicola M. , Bindon James R. , Brown Daniel E. 
Published: April 2013

ObjectivesElevated blood pressure (BP), elevated serum cholesterol, and aberrant lipoprotein fractions (low levels of high‐density lipoprotein (HDL) and high levels of low‐density lipoprotein fractions and triglycerides) have all been used as measures that assess the “metabolic syndrome” and more recently in indexes of allostatic load, which are designed to assess the degree of integrated metabolic pathology. While there are ample data regarding the interrelationships of these measures in various pathophysiological settings, there are limited data regarding the interrelationship of ambulatory BP (ABP) and blood lipids in healthy subjects. The present study evaluates ABP‐blood lipid relationships in a multiethnic sample of healthy adults.MethodsThe subjects were 37 men (age = 40.9 ± 10.7 years) and 42 women (age = 35.8 ± 10.4 years) who were employed as hotel workers in Hawaii. Each wore an ABP monitor for one midweek workday and had pressures averaged in three daily microenvironments (work, home, and during sleep). They also had fasting blood samples taken for lipid profiling.ResultsMultivariate analysis of covariance shows that there was a strong inverse relationship between HDL and both systolic (P < 0.006) and diastolic (P < 0.006) BP, overall and in each microenvironment, but no statistically significant relationships with other lipid measures.ConclusionThese results suggest lipids and BP do not act as a group in healthy adults but that higher HDL is associated with lower BP. This latter finding is consistent with research that shows that HDL promotes vasodilation via its effect on endothelial nitric oxide synthase. Am. J. Hum. Biol. 25:563–565, 2013. © 2013 Wiley Periodicals, Inc.
Interrater reliability of a phenotypic assessment tool for the ear morphology in microtia
Authors: Luquetti Daniela V. , Saltzman Babette S. , Sie Kathleen C. , Birgfeld Craig B. , Leroux Brian G. , Evans Kelly N. , Smartt James M. , Tieu David D. , Dudley Daniel J. , Heike Carrie L. 
Published: April 2013

AbstractThe Elements of Morphology Standard Terminology working group published standardized definitions for external ear morphology. The primary objective of our study was to use these descriptions to evaluate the interrater reliability for specific features associated with microtia. We invited six raters from three different subspecialities to rate 100 ear photographs on 32 features. We calculated overall and within specialty and professional experience intraclass correlation coefficients (ICC) and 95% confidence intervals. A total of 600 possible observations were recorded for each feature. The overall interrater reliability ranged from 0.04 (95% CI: 0.00–0.14) for the width of the antihelix inferior crus to 0.93 (95% CI: 0.91–0.95) for the presence of the inferior crux of the antihelix. The reliability for quantitative characteristics such as length or width of an ear structure was generally lower than the reliability for qualitative characteristics (e.g., presence or absence of an ear structure). Categories with very poor interrater reliability included anti‐helix inferior crux width (0.04, 95% CI: 0.00–0.14), crux helix extension (0.17, 95% CI 0.00–0.37), and shape of the incisura (0.14, 95% CI: 0.01–0.27). There were no significant differences in reliability estimates by specialty or professional experience for most variables. Our study showed that it is feasible to systematically characterize many of structures of the ear that are affected in microtia. We incorporated these descriptions into a standardized phenotypic assessment tool (PAT‐Microtia) that might be used in multicenter research studies to identify sub‐phenotypes for future studies of microtia. © 2013 Wiley Periodicals, Inc.
Low‐frequency electrical stimulation of a fiber tract in temporal lobe epilepsy
Authors: Koubeissi Mohamad Z. , Kahriman Emine , Syed Tanvir U. , Miller Jonathan , Durand Dominique M. 
Published: April 2013

ObjectiveSurgical resection of the temporal lobe is an effective treatment for medically intractable temporal lobe epilepsy, but can cause memory impairment. Deep brain stimulation in epilepsy has targeted gray matter structures using high frequencies, but achieved limited success. We tested the hypothesis that low‐frequency stimulation of the fornix reduces interictal epileptiform discharges and seizures in patients with intractable mesial temporal lobe epilepsy, without affecting memory.MethodsWe implanted depth electrodes in 11 patients for surgical evaluation of intractable epilepsy. Low‐frequency stimulation of the fornix occurred in 4‐hour sessions in the video‐electroencephalography unit. Mental status assessment was performed at baseline and during stimulation. We studied the effect of stimulation on hippocampal spikes and seizures.ResultsThere were no complications, and the patients were unaware of the stimulation. Fornix stimulation elicited evoked responses in the hippocampus and the posterior cingulate gyrus. Hourly Mini‐Mental Status Examination (MMSE) scores showed an increase during stimulation when compared to prestimulation MMSE, largely due to improvement in recall, possibly representing a practice effect. Hippocampal spikes were significantly reduced during and outlasting each stimulation session. Seizure odds (n = 7) were reduced by 92% in the 2 days that followed stimulation.InterpretationLow‐frequency stimulation of the fornix activates the hippocampus and other areas of the declarative memory circuit. The results of this preliminary study suggest that low‐frequency stimulation is tolerable and reduces epileptiform discharges and seizures in patients with intractable mesial temporal lobe epilepsy. A controlled clinical trial may be warranted. Ann Neurol 2013;74:223–231
From reactivation of latent HIV‐1 to elimination of the latent reservoir: The presence of multiple barriers to viral eradication
Authors: Shan Liang , Siliciano Robert F. 
Published: April 2013

AbstractThe discovery of a stable latent reservoir for HIV‐1 in resting memory CD4+ T cells provides a mechanism for lifelong persistence of HIV‐1. The long‐lived latently infected cells persist in spite of prolonged highly active antiretroviral therapy and present a major barrier to a cure of HIV‐1 infection. In this review, we discuss the current understanding of HIV‐1 persistence and latent viral infection in the context of effective antiretroviral therapy and the recent progress in purging latent viral reservoirs. Recent studies demonstrate that reactivation of latent HIV‐1 is a promising strategy for the depletion of these viral reservoirs. A thorough evaluation of the anti‐latency activity of drug candidates should include the measurement of changes in intracellular viral RNA, plasma virus levels, and the size of latent viral reservoirs, as well as potential adverse effects. Currently, there are several technical barriers to the evaluation of anti‐latency drugs in vivo. We also discuss these challenging issues that remain unresolved.
Computational evaluation of Synechococcus sp. PCC 7002 metabolism for chemical production
Authors: Vu Trang T. , Hill Eric A. , Kucek Leo A. , Konopka Allan E. , Beliaev Alexander S. , Reed Jennifer L. 
Published: April 2013

AbstractCyanobacteria are ideal metabolic engineering platforms for carbon‐neutral biotechnology because they directly convert CO2 to a range of valuable products. In this study, we present a computational assessment of biochemical production in Synechococcus sp. PCC 7002 (Synechococcus 7002), a fast growing cyanobacterium whose genome has been sequenced, and for which genetic modification methods have been developed. We evaluated the maximum theoretical yields (mol product per mol CO2 or mol photon) of producing various chemicals under photoautotrophic and dark conditions using a genome‐scale metabolic model of Synechococcus 7002. We found that the yields were lower under dark conditions, compared to photoautotrophic conditions, due to the limited amount of energy and reductant generated from glycogen. We also examined the effects of photon and CO2 limitations on chemical production under photoautotrophic conditions. In addition, using various computational methods such as minimization of metabolic adjustment (MOMA), relative metabolic change (RELATCH), and OptORF, we identified gene‐knockout mutants that are predicted to improve chemical production under photoautotrophic and/or dark anoxic conditions. These computational results are useful for metabolic engineering of cyanobacteria to synthesize value‐added products.
Polyelectrolyte properties of single stranded DNA measured using SAXS and single‐molecule FRET: Beyond the wormlike chain model
Authors: Meisburger Steve P. , Sutton Julie L. , Chen Huimin , Pabit Suzette A. , Kirmizialtin Serdal , Elber Ron , Pollack Lois 
Published: April 2013

ABSTRACTNucleic acids are highly charged polyelectrolytes that interact strongly with salt ions. Rigid, base‐paired regions are successfully described with wormlike chain models, but nonbase‐paired single stranded regions have fundamentally different polymer properties because of their greater flexibility. Recently, attention has turned to single stranded nucleic acids due to the growing recognition of their biological importance, as well as the availability of sophisticated experimental techniques sensitive to the conformation of individual molecules. We investigate polyelectrolyte properties of poly(dT), an important and widely studied model system for flexible single stranded nucleic acids, in physiologically important mixed mono‐ and divalent salt. We report measurements of the form factor and interparticle interactions using SAXS, end‐to‐end distances using smFRET, and number of excess ions using ASAXS. We present a coarse‐grained model that accounts for flexibility, excluded volume, and electrostatic interactions in these systems. Predictions of the model are validated against experiment. We also discuss the state of all‐atom, explicit solvent molecular dynamics simulations of poly(dT), the next step in understanding the complexities of ion interactions with these highly charged and flexible polymers. © 2013 Wiley Periodicals, Inc. Biopolymers 99: 1032–1045, 2013.