bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fatal multiple acyl-CoA dehydrogenase deficiency caused by ETFDH gene mutation: A case report
Authors: Li Xue-Xia , Yang Xiao-Nan , Pan Hu-Dan , Liu Liang 
Published: July 2024

BACKGROUND
Multiple acyl-CoA dehydrogenase deficiency (MADD) is a disease of rare autosomal recessive disorder. There are three types of MADD. Type I is a neonatal-onset form with congenital anomalies. Type II is a neonatal-onset form without congenital anomalies. Type III is considered to a milder form and usually responds to riboflavin. However, late-onset form could also be fatal and not responsive to treatments.
CASE SUMMARY
We report a severe case of a young man with onset type III MADD induced by drugs and strenuous exercise characterized by rhabdomyolysis and liver dysfunction. Urine analysis indicated 12 out of 70 kinds of organic acids like glutaric acid-2 were detected. Serum analysis in genetic metabolic diseases revealed 24 out of 43 tested items were abnormal, revealing the elevation of several acylcarnitines and the reduction of carnitine in the patient. By next generation sequencing technology for gene sequencing related to fatty acid oxidation and carnitine cycle defects, a rare ETFDH gene variant was identified: NM_004453:4:C.1448C>T(p.Pro483 Leu). The patient was diagnosed with late-onset GAII. He was not responsive to riboflavin and progressively worsened into multiple organ failure that finally led to death.
CONCLUSION
Type III MADD can also be fatal and not responsive to treatments.
Space optical communication system for space optical networks and deep space exploration
Authors: Wang Jianmin , Li Bin , Gao Haochun , Lin Yang , Su Zhiqian 
Published: July 2024

The acquisition time of tens to hundreds of seconds in the optical link between satellites makes it difficult to meet the needs of constructing spatial optical networks. In addition, as a basic requirement for deep space explorers, autonomous attitude determination and autonomous navigation demand the installation of separate, expensive, and complex inertial devices, and the communication data rate is too low to meet the timely transmission of large amounts of data. In this paper, we proposed and developed a multifunctional fusion space optical communication system for space optical networks and deep space exploration, which has the functions of autonomous attitude determination, autonomous navigation, and high-speed optical communication. The sub-second acquisition time can meet the requirements of space optical network construction, and the ability of autonomous attitude determination and autonomous navigation significantly reduce the amount of R&D expenses of the explorer; decrease the volume, weight, and power consumption of the explorer; and improve the reliability and autonomous survival ability of the explorer. The paper provides the structure, working principle, and main algorithm models and conducts a feasibility analysis and field experiments. The experimental results showed that the average open-loop pointing accuracy of the optical terminal is 95.8 µrad (attitude determination accuracy), which can be improved to 39.1 µrad after filtering, and the acquisition time is less than 1 s. For deep space exploration, the navigation accuracy is less than 67.6 km in the cruise phase and 10 km in the acquisition phase, and field experiments have also proven its feasibility. The significance of our research work lies in proposing what we believe to be a new system operation scheme and design method for optical communication systems, and its results can be widely applied in all fields of space optical communication.
Serological diagnosis of strongyloidiasis: An evaluation of three commercial assays
Authors: Weitzel Thomas , Dittrich Sabine , Mockenhaupt Frank P. , Lindner Andreas K. 
Published: July 2024

Background
Strongyloidiasis is caused by a neglected nematode, manifesting as chronic intestinal infection with potentially severe manifestations. The disease is an emerging problem in non-endemic countries affecting travelers and migrants. Diagnosis of strongyloidiasis is hampered by the lack of standardization and absence of a gold standard. Since adequate direct methods to detect the motile larvae in stool samples are not widely available, other techniques such as serology have been developed.

Methods
We evaluated three commercial ELISA kits (DRG Instruments, IVD Research, and Bordier Affinity Products) to detect IgG antibodies against Strongyloides stercoralis assays utilizing serum samples from travelers with microscopically confirmed strongyloidiasis (n = 50) and other imported helminthic infections (n = 159) as well as healthy controls (n = 50).

Results
The DRG, IVD, and Bordier assays showed sensitivities of 58.0%, 64.0%, and 56.0%, respectively. Specificity values were 96.0%, 96.0%, and 92.0% in healthy controls, and 67.3%, 62.9%, and 76.7% in cases with other helminth infections, respectively. Cross-reactions were mostly observed in cases with other nematodes (37.5%, 42.5%, and 20.0%, respectively), but also in trematode (33.3%, 38.1%, and 19.0%, respectively) and in cestode infections (25.0%, 30.0%, and 32.5%, respectively).

Conclusion
The study demonstrates the diagnostic limitations of serological assays to detect or exclude cases of strongyloidiasis in returning travelers, who frequently present with recent or acute infections.
Cardiorespiratory dynamics of type 2 diabetes mellitus: An extensive view of breathing and fitness challenges in a diabetes prevalent population
Authors: Abbas Uzair , Shah Shahbaz Ali , Babar Nisha , Agha Pashmina , Khowaja Mohiba Ali , Nasrumminallah Maryam , Arif Hibba Erum , Hussain Niaz , Hasan Syed Mustafa , Baloch Israr Ahmed 
Published: July 2024

Background
Diabetes mellitus (DM) is well known for related micro and macrovascular complications. Uncontrolled hyperglycemia in diabetes mellitus leads to endothelial dysfunction, inflammation, microvascular impairment, myocardial dysfunction, and skeletal muscle changes which affect multiple organ systems. This study was designed to take an extensive view of cardiorespiratory dynamics in patients with type 2 DM.

Methods
One hundred healthy controls (HC) and 100 DM patients were enrolled. We measured and compared the breathing patterns (spirometry), VO2 max levels (heart rate ratio method) and self-reported fitness level (international fitness scale) of individuals with and without diabetes. Data was analyzed in SPSS v.22 and GraphPad Prism v8.0.

Results
We observed restrictive spirometry patterns (FVC <80%) in 22% of DM as compared to 2% in HC (p = 0.021). There was low mean VO2 max in DM as compared to HC(32.03 ± 5.36 vs 41.91 ± 7.98 ml/kg/min; p value <0.001). When evaluating physical fitness on self-reported IFiS scale, 90% of the HC report average, good, or very good fitness levels. In contrast, only 45% of the DM shared this pattern, with a 53% proportion perceiving their fitness as poor or very poor (p = <0.05). Restrictive respiratory pattern, low VO2 max and fitness level were significantly associated with HbA1c and long-standing DM.

Conclusion
This study shows decreased pulmonary functions, decreased cardiorespiratory fitness (VO2 max) and IFiS scale variables in diabetic population as compared to healthy controls which are also associated with glycemic levels and long-standing DM. Screening for pulmonary functions can aid optimum management in this population.
Prevalence of traditional uvulectomy and its associated factors among parents who had less than 6 months of infants in Gondar City, north-west Ethiopia: Mixed study design
Authors: Bazezew Lakachew Yismaw , Dagne Asrat Hailu , Kassie Destaye Guadie , Desta Abebaw Alemayehu , Gobeza Mengistu Berhan 
Published: July 2024

Background
Traditional uvulectomy is widely practiced in Africa especially in sub-Saharan countries including Ethiopia. Limited Studies conducted in different times and areas of the world have shown that the prevalence of uvulectomy and its associated factors are varied from country to country. There is limited evidence to determine the prevalence and reasons of malpractice in Ethiopia. Therefore, this study aimed to assess the prevalence of traditional uvulectomy, and its associated factors among parents who had children aged less than 6 months.

Methods
A community-based cross-sectional mixed study design was conducted among 630 participants selected by a systematic sampling technique. Data were collected using a pretested interviewer-administered questionnaire. The collected data were entered into Epi-data, and analyzed by using STATA version 14software. Descriptive statistics were computed and presented using tables, figures and texts. Factors associated with the prevalence of uvulectomy were selected for multiple logistic regressions at the probability value (p-value) of less than 0.2 in the X2- analysis. Statistically significant associated factors were identified at the probability value (p-value) less than 0.05 and adjusted OR (AOR) with a 95% CI. A total of 10 individual depth interviewees and 5 key informants were included using purposive sampling techniques. For the qualitative study, and thematic content analysis was employed to analyze the data, which were transcribed, translated, coded, screened, thematized, analyzed, synthesized, and finally supplemented the quantitative finding.

Results
The prevalence of traditional uvulectomy was 84.60% (CI: 81.77%n—87.42%). Being rural residence (adjusted OR = 2.08, CI = 1.06–4.12), mothers aged 30 to 34 years (adjusted OR = 2.9, CI = 1.28–6.60), having no antenatal care visit (adjusted OR = 3.91, CI = 1.33–11.47), having no bad obstetric history (adjusted OR = 2.11, CI = 1.12–3.98), having no postnatal care visit (adjusted OR = 3.88, CI = 1.36–11.12) and mothers’ poor attitude (adjusted OR = 3.32, CI = 2.01–5.47) were statistically significant associated factors of traditional uvulectomy. Seeking traditional uvulectomy, lack of information and third-party pressure were the main themes of the qualitative study that support the findings of the quantitative study.

Conclusion
The prevalence of traditional uvulectomy was high. Being rural residents, mothers aged 30 to 34 years, having no antenatal care visit, having no complications of obstetric history, having no postnatal care visit and mothers with poor attitude were statistically significant associated factors of traditional uvulectomy. Lack of information about uvulectomy and third-party pressure was the reason for seeking traditional uvulectomy.
Synergistic impact of psoriasis and hypertension on all-cause mortality risk: A prospective cohort study
Authors: Zhao Honglei , Wu Ji , Wu Qianqian 
Published: July 2024

Background
The linkage between psoriasis and hypertension has been established through observational studies. Despite this, a comprehensive assessment of the combined effects of psoriasis and hypertension on all-cause mortality is lacking. The principal aim of the present study is to elucidate the synergistic impact of psoriasis and hypertension on mortality within a representative cohort of adults residing in the United States.

Methods
The analysis was conducted on comprehensive datasets derived from the National Health and Nutrition Examination Study spanning two distinct periods: 2003–2006 and 2009–2014. The determination of psoriasis status relied on self-reported questionnaire data, whereas hypertension was characterized by parameters including systolic blood pressure ≥ 140 mmHg, diastolic blood pressure ≥ 90 mmHg, self-reported physician diagnosis, or the use of antihypertensive medication. The assessment of the interplay between psoriasis and hypertension employed multivariable logistic regression analyses. Continuous monitoring of participants’ vital status was conducted until December 31, 2019. A four-level variable amalgamating information on psoriasis and hypertension was established, and the evaluation of survival probability utilized the Kaplan-Meier curve alongside Cox regression analysis. Hazard ratios (HRs) and their associated 95% confidence intervals (CIs) were computed to scrutinize the correlation between psoriasis/hypertension and all-cause mortality.

Results
In total, this study included 19,799 participants, among whom 554 had psoriasis and 7,692 had hypertension. The findings from the logistic regression analyses indicated a heightened risk of hypertension among individuals with psoriasis in comparison to those devoid of psoriasis. Throughout a median follow-up spanning 105 months, 1,845 participants experienced all-cause death. In comparison to individuals devoid of both hypertension and psoriasis, those with psoriasis alone exhibited an all-cause mortality HR of 0.73 (95% CI: 0.35–1.53), individuals with hypertension alone showed an HR of 1.78 (95% CI: 1.55–2.04), and those with both psoriasis and hypertension had an HR of 2.33 (95% CI: 1.60–3.40). In the course of a stratified analysis differentiating between the presence and absence of psoriasis, it was noted that hypertension correlated with an elevated risk of all-cause mortality in individuals lacking psoriasis (HR 1.77, 95% CI: 1.54–2.04). Notably, this association was further accentuated among individuals with psoriasis, revealing an increased HR of 3.23 (95% CI: 1.47–7.13).

Conclusions
The outcomes of our investigation demonstrated a noteworthy and positive association between psoriasis, hypertension, and all-cause mortality. These findings indicate that individuals who have both psoriasis and hypertension face an increased likelihood of mortality.
Unveiling the urban sports landscape: Profiling participants, motives, and policy implications
Authors: Huyghe Jef , D’Hoore Nathan , Thibaut Erik , Scheerder Jeroen 
Published: July 2024

Background
The lack of knowledge regarding urban sports poses pressing challenges for governments and sports organisations to deal with in light of its increasing popularity. To develop targeted policy strategies, more insight is needed into the features of urban sports. Therefore, this research aims to establish a profile of urban sports participants in terms of characteristics, behaviours in sports participation, and motives for sports participation.

Methods
Data was gathered during a large-scale research project on sports participation in the Belgian city of Bruges. A total of 3,951 residents between 6 and 75 years old participated in an online survey. Descriptive statistics and binomial logistic regression analyses were used to examine the differences between urban and traditional sports participants.

Results
Based on a binomial regression model, the sports level and location significantly predict urban sports participation. The physical motives for sports participation are significantly less important for urban sports participants compared to the group of traditional sports participants. Urban sports participants value the fun and relaxation motives for sports participation significantly more than traditional sports participants.

Conclusions
This paper aimed to establish a comprehensive profile of urban sports participants and juxtaposed it to that of traditional sports participants. While existing literature often portrays urban sports participants as a relatively homogeneous group, our findings reveal a surprising heterogeneity. Consequently, given its increasing popularity, urban sports present a valuable avenue for governments and sports organisations to engage with a diverse range of sports participants.
Incidence and predictors of tuberculosis among HIV-infected children after initiation of antiretroviral therapy in Ethiopia: A systematic review and meta-analysis
Authors: Kassaw Amare , Asferie Worku Necho , Azmeraw Molla , Kefale Demewoz , Kerebih Gashaw , Mekonnen Gebrehiwot Berie , Baye Fikadie Dagnew , Zeleke Shegaw , Beletew Biruk , Kebede Solomon Demis , Aytenew Tigabu Munye , Bazezew Lakachew Yismaw , Agimas Muluken Chanie 
Published: July 2024

Background
Globally, Tuberculosis (TB) is the main cause of morbidity and mortality among infectious disease. TB and Human Immune Virus (HIV) are the two deadly pandemics which interconnected each other tragically, and jeopardize the lives of children; particularly in Sub-Saharan Africa. Therefore, this review was aimed to determine the aggregated national pooled incidence of tuberculosis among HIV- infected children and its predictors in Ethiopia.

Methods
An electronic search engine (HINARI, PubMed, Scopus, web of science), Google scholar and free Google databases were searched to find eligible studies. Quality of the studies was checked using the Joanna Briggs Institute (JBI) quality assessment checklists for cohort studies. Heterogeneity between studies was evaluated using Cochrane Q-test and the I2 statistics.

Result
This review revealed that the pooled national incidence of tuberculosis among children with HIV after initiation of ART was 3.63% (95% CI: 2.726–4.532) per 100-person-years observations. Being Anemic, poor and fair ART adherence, advanced WHO clinical staging, missing of cotrimoxazole and isoniazid preventing therapy, low CD4 cell count, and undernutrition were significant predictors of tuberculosis incidence.

Conclusion
The study result indicated that the incidence of TB among HIV- infected children is still high. Therefore, parents/guardians should strictly follow and adjust nutritional status of their children to boost immunity, prevent undernutrition and opportunistic infections. Cotrimoxazole and isoniazid preventive therapy need to continually provide for HIV- infected children for the sake of enhancing CD4/immune cells, reduce viral load, and prevent from advanced disease stages. Furthermore, clinicians and parents strictly follow ART adherence.
Media Activism, Artivism and the Fight against Marginalisation in the Global South: South-to-South Communication, A. Medrado and I. Rega (2023)
Authors: González Maricruz Barba 
Published: July 2024

Review of: Media Activism, Artivism and the Fight against Marginalisation in the Global South: South-to-South Communication, A. Medrado and I. Rega (2023)
New York: Routledge, 174 pp.,
ISBN 978-1-00321-510-3, e-book, CAD 41.14
Notación indeterminada, tradición interpretativa y reproductibilidad técnica: hacia una perspectiva crítica para la realización de obras experimentales indeterminadas
Authors: Alvear M. Cristián 
Published: July 2024

Este estudio aborda, desde un punto de vista teórico, la interpretación de música experimental indeterminada de origen estadounidense en tanto práctica cuyo desarrollo se ha sustentado en los postulados de la Escuela de Nueva York. En este ámbito, se examinan nociones interpretativas habituales, las cuales, al sostener un modo directo y no mediado para la elaboración de los sonidos de una obra, resultan problemáticas. Para esto, se establece una conexión entre realización y el régimen subjetivo que instaura la reproductibilidad técnica (Benjamin, 2020). El propósito es develar el modo en que los objetos seriales propios de un ámbito determinan el dialecto del intérprete permitiéndole a este conformar versiones que cumplan con las expectativas de dicho ámbito (Mattes, 2015). En este sentido, nociones discursivas y prácticas son examinadas según dos aspectos propios de toda notación: la prescripción y la descripción (Kanno, 2007). En tanto conceptos habilitantes, estos permiten vislumbrar las convenciones que la interpretación, dado el marco en el que se desenvuelve, reproduce. De este modo, este estudio contribuye a sentar las bases para una perspectiva interpretativa consciente de la tradición que la informa, en pos de habilitar la exploración crítica y, además, ampliar los alcances de una práctica indeterminada.
El videoclip como ventana de lo posible
Authors: Millán Camila 
Published: July 2024

En este artículo analizamos, desde una perspectiva feminista, el videoclip y la canción «It's raining men» publicada en 1982 por The weather girls. Esta obra y su devenir como himno disidente funcionan como un hito que permite comprender los modos en los que se relacionan las estéticas y estrategias artísticas con los caminos disruptivos de las canciones, en el marco de la música popular y masiva industrializada. Las repercusiones de este single en las pistas de baile de los principales centros urbanos de Estados Unidos, así como los recorridos que posibilitaron su existencia, resultan un espacio privilegiado para pensar las relaciones entre música, políticas sexuales, cuerpos, performatividad, industria, representaciones visuales, política y disputas públicas.

El trabajo se realizó entendiendo al video musical como una extensión de la canción en el marco de la cultura mediática. Partiendo de la idea de que la música popular masiva engloba una serie de prácticas y operaciones que involucran aspectos técnicos, musicales, tradicionales, vinculados a la industria, los mercados y los modos de producción, circulación, legitimación y valoración de las músicas; y que por tanto, la música popular es social y compleja, analizamos el videoclip a partir de la metodología de Soares, ya que permite reponer nociones vinculadas al montaje como recurso expresivo y político, haciendo posible el abordaje performático, corpóreo y mediático de los sentidos vehiculizados en la música.
Reseña de En el final de aquel verano interminable de Gerardo Gandini (prólogo de Ricardo Piglia - edición de Pablo Fessel y Ezequiel Grimson). Gourmet Musical, 2023
Authors: Domínguez Pesce Agustín 
Published: July 2024

Gandini se ha convertido en una figura sin igual en la música de concierto de Argentina. Sin embargo, la interpretación musicológica de su producción, rica en cuanto a las capas de intertextualidad, está en proceso de construcción y se ha expresado en importantes trabajos de Pablo Fessel.
La presente reseña del libro En el final de aquel verano interminable de Gerardo Gandini, editado por Pablo Fessel y Ezequiel Grimson, procura poner de relieve la relevancia de la publicación para el estudio de la historia cultural así como de la historia de la música contemporánea de Argentina. En la reseña se recorren las diferentes secciones del libro, procurando señalar la riqueza de su contenido y los potenciales destinatarios, tales como intérpretes y directores de la música de Gandini, pero también estudiantes de composición e investigadores interesados en la línea de la propia interpretación.
Se destaca la importancia de la reunión de todos estos documentos en una única compilación. Son documentos que se tornan necesarios para el estudio de la poética compositiva de Gandini, como también para la dimensión de la música como performance. No menos importante son los documentos que aportan información sobre la historia de las instituciones de la música de concierto de Argentina en la segunda mitad del siglo XX. El libro permite construir una interpretación de Gandini como figura compleja dentro del entramado de la música contemporánea de Argentina, en particular, de la ciudad de Buenos Aires. La reseña procura mostrar algunas líneas de utilización de estos documentos para su aplicación en la investigación sociológica e historiográfica de la música, considerando como potenciales destinatarios a jóvenes investigadores. La misma concluye convocando la clave autobiográfica del libro, por lo que se anticipan algunas de las ideas con que Ricardo Piglia lo preludia.