bluuebunny/crossref_metadata_2025_split huggingface dataset:
Glycoside hydrolase PpGH28BG1 modulates benzaldehyde metabolism and enhances fruit aroma and immune responses in peach
Authors: Jiang Dan , Han Qingyuan , Su Yike , Cao Xiangmei , Wu Boping , Wei Chunyan , Chen Kunsong , Li Xian , Zhang Bo 
Published: August 2024

Abstract
Benzaldehyde (BAld) is one of the most widely distributed volatiles that contributes to flavor and defense in plants. Plants regulate BAld levels through various pathways, including biosynthesis from trans-cinnamic acid (free BAld), release from hydrolysis of glycoside precursors (BAld-H) via multiple enzymatic action steps, and conversion into downstream chemicals. Here, we show that BAld-H content in peach (Prunus persica) fruit is up to 100-fold higher than that of free BAld. By integrating transcriptome, metabolomic, and biochemical approaches, we identified glycoside hydrolase PpGH28BG1 as being involved in the production of BAld-H through the hydrolysis of glycoside precursors. Overexpressing and silencing of PpGH28BG1 significantly altered BAld-H content in peach fruit. Transgenic tomatoes heterologously expressing PpGH28BG1 exhibited a decrease in BAld-H content and an increase in SA accumulation, while maintaining fruit weight, pigmentation, and ethylene production. These transgenic tomato fruits displayed enhanced immunity against Botrytis cinerea compared to wild type (WT). Induced expression of PpGH28BG1 and increased SA content were also observed in peach fruit when exposed to Monilinia fructicola infection. Additionally, elevated expression of PpGH28BG1 promoted fruit softening in transgenic tomatoes, resulting in a significantly increased emission of BAld compared to WT. Most untrained taste panelists preferred the transgenic tomatoes over WT fruit. Our study suggests that it is feasible to enhance aroma and immunity in fruit through metabolic engineering of PpGH28BG1 without causing visible changes in the fruit ripening process.
Podoconiosis in Uganda: prevalence, geographical distribution and risk factors
Authors: Masete Ivan , Simpson Hope , Matwale Gabriel , Mutebi Francis , Thielecke Marlene , Nuwaha Fred , Mukone George , Deribe Kebede , Davey Gail 
Published: August 2024

Abstract

Background
Podoconiosis is a neglected debilitating yet preventable disease. Despite its public health significance, podoconiosis is often misdiagnosed and confused with lymphatic filariasis. No appropriate diagnostic tests exist, contributing to underestimation and the absence of control interventions.

Methods
A population-based cross-sectional survey was conducted in seven districts with suspected or reported cases of podoconiosis or an altitude of 1200 m above sea level. Conducted from 30 January to 19 March 2023, the survey employed multilevel stratified sampling to reach eligible household members.

Results
Of the 10 023 participants sampled, 187 (confidence interval 1.25 to 2.78) had clinical features of podoconiosis. The highest prevalence was recorded in Nakapiripirit (7.2% [58/809]) and Sironko (2.8 [44/1564]) and the lowest in Kasese (0.3% [5/1537]), but ranged from 1.1 to 1.8% in Zombo, Rukungiri, Gomba and Hoima districts. The duration of podoconiosis was reported to range from 1 to 57 y. Factors associated with podoconiosis occurrence included advanced age, tungiasis, household cleanliness and personal hygiene. Sleeping on a bed, bathing daily, use of soap and use of footwear in at least moderate condition were protective against podoconiosis.

Conclusions
Podoconiosis occurred in all the sampled districts and was linked to personal hygiene. Long-standing cases suggest an absence of treatment. There is potential for early intervention using a holistic care model in managing this condition. Urgent action and stakeholder engagement are essential for effective podoconiosis management.
The new EU asylum laws: taking rights half-seriously
Authors: Peers Steve 
Published: August 2024

Abstract
The EU has finally adopted comprehensive amendments to its asylum laws. To what extent are those changes compatible with human rights? This article examines this question by reference to the new laws on qualification, procedures, responsibility for asylum applications, reception and screening of asylum seekers, and resettlement of refugees, compared to the prior legislation (and case law). The main themes of the new laws are restraining movements of asylum seekers between Member States, coupled with further harmonization of the law. While the new Pact attempts to reach a compromise between immigration control and human rights, the article argues that such a compromise could prove to be uneasy and unstable.
Burden of digestive system diseases in China and its provinces during 1990–2019: Results of the 2019 Global Disease Burden Study
Authors: Cheng Zhiyuan , Wang Tinglu , Jiao Yunfei , Qi Jinlei , Zhang Xun , Zhou Siwei , Xin Lei , Wan Rong , Zhou Maigeng , Li Zhaoshen , Wang Luowei 
Published: August 2024

Article

Background:
Evaluating the impact of digestive system diseases is vital for devising effective prevention strategies. However, comprehensive reports on the burden of digestive system diseases in China are lacking. Our study aimed to provide an overview of the burden and trends of digestive system diseases from 1990 to 2019 in China and its provinces.

Methods:
This cross-sectional study utilized the Global Disease Burden Study 2019 to estimate the incidence, mortality rate, disability-adjusted life years (DALYs), years of life disability, years of life lost, and changes in the burden of digestive diseases across 31 Chinese provinces from 1990 to 2019. The analysis of disease burden primarily examines the characteristics of sub-disease distribution, time trends, age distribution, and sex distribution. Additionally, we compared provincial age-standardized DALYs for digestive diseases with the expected rates based on the socio-demographic index (SDI).

Results:
In 2019, there were 499.2 million cases of digestive system diseases in China, resulting in 1,557,310 deaths. Stomach cancer, colon and rectal cancer, and esophageal cancer are the top three diseases associated with mortality and DALY related to digestive system diseases. Meanwhile, cirrhosis and other chronic liver diseases, gastroesophageal reflux disease, and gallbladder and biliary diseases are the top three kinds of diseases with the highest prevalence among digestive system diseases. The risk of gastric cancer sharply increases among men after the age of 40 years, leading to a significant disparity in burden between men and women. As the SDI increased, the DALYs associated with digestive system diseases in China and its provinces showed a downward trend.

Conclusion:
Our study highlights the inverse correlation between DALYs associated with digestive system diseases and the SDI, providing valuable insights that can assist public health officials in the estimation of the disease burden in this area.
Transdisciplinary architectures: reconnecting theories, research and practices
Authors: Lawrence Roderick John 
Published: August 2024

PurposeTransdisciplinarity was the core subject of a special issue of Futures in 2004 including numerous cases of interdisciplinary and transdisciplinary architectural and urban research and professional practice in several countries. This paper takes stock of achievements during the last 20 years before presenting challenges about bridging persistent gaps between theory, research and practice.Design/methodology/approachThe special issue of Futures is a benchmark for numerous publications about transdisciplinarity in and beyond the multidisciplinary and intersectoral field of built environments. This paper presents a narrative literature review of publications about transdisciplinarity in architecture, urban design and planning since the 1970s.FindingsTransdisciplinarity is still being debated, is often contested, and is not mainstream in research or practice. Like design practice, transdisciplinary inquiry is a creative process involving border work by participants in collaborative projects. Transdisciplinary inquiry is broader in scope and purpose than public participation, participatory action research and team science.Originality/valueThis paper discusses challenges that should be addressed by those in the field of built environments who endorse transdisciplinarity. Based on a half century of contributions about design theory and methods, the paper differentiates inquiry from research as fundamental to transdisciplinary projects.
Exploring interconnections and risk evaluation of green equities and bonds: fresh perspectives from TVP-VAR model and wavelet-based VaR analysis
Authors: Yousfi Mohamed , Bouzgarrou Houssam 
Published: August 2024

PurposeThis study attempts to examine the time-varying volatility spillovers between environmentally sustainable assets and quantify the value-at-risk of the portfolios across various frequencies.Design/methodology/approachTo accomplish these objectives, this paper utilizes a connectedness index-based TVP-VAR model and applies the wavelet-based VaR ratio to daily data spanning from January 2018 to September 2023.FindingsThe empirical findings reveal a notable increase in the connectedness index between green stocks and green bonds during the COVID-19 crisis, signifying evidence of a contagion effect. The portfolio’s risk ratio also exhibited a sharp rise amid the pandemic, particularly over medium and long-term horizons, driven by increased spillover among green assets. Notably, our analysis indicates that green bonds influence the connectedness system between green stocks and the value-at-risk ratio, reducing volatility spillover and portfolio risk ratios across various investment horizons. These results highlight the role of green bonds as an effective diversification asset against the risks associated with green equities.Originality/valueThis research investigates the dynamic connectedness and value-at-risk ratio between eight green sectoral renewable energy and non-energy equities and green bonds. We put forward some portfolio implications for green investors with an environmental consciousness who desire to decarbonize their portfolios and mitigate environmental issues.
Optimizing the third mission of higher education institutions by predicting teaching behavior
Authors: Souza Diego Fillipe de , Azevedo Érika Sabrina Felix , Mendonça José Ricardo Costa de 
Published: August 2024

PurposeThis article aims at presenting the concept of the Brazilian university’s third mission and its relevance for predicting teaching behavior. To that end, this article presents a conceptual model of that third mission in Brazil and how its relationship with stakeholders was built.Design/methodology/approachThis is a conceptual article. The authors analyze the third mission and the Brazilian educational model to suggest predicting teaching behavior as a possibility to optimize the third mission in higher education institutions.FindingsThe Brazilian third mission is related to civilian participation, John Dewey’s democratic education management, Paulo Freire’s transformative education, Triple-Helix and the knowledge ecology. This association enables insight into the relevance of the third mission and into the need for professors’ participation.Practical implicationsRevealing the factors of behavior prediction to perform the third mission is the first mission of the theory of planned behavior. Based on these data, the theory suggests interventions without changing teaching behavior. This possibility might increase the adherence of the professor to activities related to the third mission.Originality/valueThis article contributes to studies on the development of the third mission and to the sharing of a conceptual model that is partially different from the European model, thus promoting broader results for stakeholders. The indications made here can lead to empirical studies to further approximate the higher education institutions and the various sectors of society. Moreover, there is room for investigations that aim at a conceptual convergence at the international level for the third mission, as it happens for teaching and researching.
The marginalisation of responsible management in business schools: a consideration of future trajectories
Authors: Ndubuka-McCallum Nkeiruka N. , Jones David R. , Rodgers Peter 
Published: August 2024

Purpose
Business schools are vital in promoting responsible management (RM) – a management grounded in ethics and values beneficial to a wide array of stakeholders and overall society. Nevertheless, due to deeply embedded institutional modernistic dynamics and paradigms, RM is, despite its importance, repeatedly marginalised in business school curricula. If students are to engage with RM thinking, then its occlusion represents a pressing issue. Drawing on the United Kingdom (UK) business school context, this paper aims to examine this issue through a framework of institutional theory and consider the role played by (modernistic) institutional accreditation and research assessment processes in marginalisation of RM.

Design/methodology/approach
This study used an exploratory qualitative research method. Data were collected from 17 RM expert participants from 15 UK business schools that were signatories to the United Nations Principles for Responsible Management Education through semi-structured in-depth interviews and analysed using the six phases of Braun and Clarke’s thematic analysis.

Findings
The study identifies a potent institutional isomorphic amalgam resulting in conservative impacts for RM. This dynamic is termed multiple institutional isomorphic marginalisation (MIIM) – whereby a given domain is occluded and displaced by hegemonic institutional pressures. In RM’s case, MIIM operates through accreditation-driven modernistic-style curricula. This leads business schools to a predilection towards “mainstream” representations of subject areas and a focus on mechanistic research exercises. Consequently, this privileges certain activities over RM development with a range of potential negative effects, including social impacts.

Originality/value
This study fills an important gap concerning the need for a critical, in-depth exploration of the role that international accreditation frameworks and national institutional academic research assessment processes such as the Research Excellence Framework in the UK play in affecting the possible growth and influence of RM. In addition, it uses heterotopia as a conceptual lens to reveal the institutional “mask” of responsibility predominantly at play in the UK business school context, and offers alternative pathways for RM careers.
Digital transformation in sales organizations: antecedents of sales managers’ change readiness and championing behaviors
Authors: Badrinarayanan Vishag , Rangarajan Deva , Lai-Bennejean Christine , Bowen Melanie , Kaski Timo Arvid 
Published: August 2024

Purpose
Although organizations are investing heavily in digital transformation (DT) of the sales function, implementation and exploitation at the sales force level are ongoing challenges. As sales managers serve as conduits of influence between top management and the sales force, the success of strategic initiatives, such as DT, hinges heavily on leveraging their influence to promote change adoption at the sales force level. Accordingly, this research is guided by the research question: how can sales organizations secure the buy-in of sales managers and induce their championing behaviors directed toward the sales force?. The purpose of this paper is to investigate how organizational and psychological resources influence sales managers' DT change champion through their change readiness.

Design/methodology/approach
Construing DT in sales as an organizational change that creates contextual job demands, the theoretical framework offers several hypotheses linking organizational and personal resources with sales managers’ change readiness and championing behaviors. The perceived impact of change is included as a moderating variable. Using data from a sample of 176 business-to-business sales managers, the hypotheses are tested using partial least squares structural equation modeling.

Findings
The authors demonstrate that two change-related organizational resources (change communication and change mobilization) and a personal psychological resource (psychological capital) facilitate sales managers’ emotional and cognitive change readiness, which, in turn, enhances their championing behaviors toward DT initiatives. Further, the authors find that perceived change impact augments the effects of organizational and psychological resources on change readiness, thus highlighting the importance of effective positioning of the outcomes of change.

Practical implications
This study provides practitioners with actionable guidance on securing the buy-in of sales managers for change initiatives such as DT. Specifically, communication and mobilization are critical inducements. Managers who score high on psychological capital can be targeted as change agents. Further, the impact of change needs to be framed positively, as the resultant perceptions magnify the effects of organizational resources.

Originality/value
While prior research has examined salespeople’s response to change, very little is known about the antecedents of change readiness and championing behavior among sales managers. Based on the results, the authors identify theoretical and managerial implications as well as future research directions.
Antecedents and consequences of automated VAT solution adoption in Gulf cooperation countries: the case of the United Arab Emirates
Authors: Al-Hiyari Ahmad , Kolsi Mohamed Chakib , Mas’ud Abdulsalam 
Published: August 2024

Purpose
This paper aims to examine the antecedents of the Automated VAT Solution (AVS) and its eventual consequence on value-added tax (VAT) compliance costs among the small and medium enterprises (SMEs) in Gulf Cooperation Countries (GCC), with the United Arab Emirates (UAE) as context.

Design/methodology/approach
A quantitative research design was deployed through a survey of 576 SMEs in the UAE. The data was analyzed using Partial Least Squares Structural Equation Modeling (PLS-SEM).

Findings
The findings revealed that technological factors (IT complexity and IT competency) and organizational factors (management support and size of SME) significantly influence AVS adoption. However, only consumer pressure was found to be significant among the environmental factors, and AVS adoption was found to have a significant negative effect on the VAT compliance cost.

Research limitations/implications
A lower coefficient of determination for the effect of AVS adoption on VAT compliance cost meant that there may be other accounting-related technologies that improve operational efficiency and process automation and, in the long run, lower the cost of VAT compliance. These technologies should be included in future studies.

Practical implications
The findings imply that the adoption of AVS among SMEs is highly desirable, as it reduces VAT compliance costs. Increased regulatory pressure by the UAE’s policymakers is also desirable to accelerate AVS adoption for enhanced cost reduction and revenue maximization from the perspectives of both the government and SMEs.

Originality/value
To the best of the authors’ knowledge, this study could be the first to expand the Technology-Organization-Environmental (TOE) Framework through the integration of determinants of AVS adoption and VAT compliance costs among SMEs in GCC countries.
Unveiling the terrain of non-bank Islamic personal financing: current practices, challenges, and future prospects
Authors: Ilias Ibtisam @ Ilyana , Nasrun Mastika , Muhamed Nurul Aini 
Published: August 2024

Purpose
This study aims to investigate the current practices among selected non-bank financial institutions (NBFIs) in Malaysia in offering Islamic personal financing and the multiple challenges faced by them.

Design/methodology/approach
The qualitative research methodology was used, and primary data was collected using semi-structured interviews with 10 respondents consisting of NBFIs’ representatives and Shariah advisors.

Findings
Most Islamic personal financing practice is based on tawarruq. Among the major challenges faced by NBFIs are the absence of a comprehensive legal framework, Shariah non-compliance risks, cost, human resources and risk management. Recommendations include establishing a proper legal framework and Shariah governance. The study also recommends centralising at the regulatory level aspects such as training, commodity murabahah system and the department performing the Shariah advisory and control functions.

Research limitations/implications
Online interviews were conducted during the early wave of the COVID-19 pandemic in 2020 with a limited number of respondents due to people’s hesitancy to participate during the pandemic.

Practical implications
The findings will guide regulators and industry players concerning the challenges that must be addressed and the recommendations that can be considered in ensuring complete adherence to Shariah principles for the offering of personal financing. Eventually, Muslim society in need of cash will benefit from the broader choice of Shariah-compliant personal financing.

Social implications
The research highlights the weaknesses of self-regulation in guaranteeing Shariah compliance and the need for regulatory intervention.

Originality/value
This is a pioneering empirical study that investigated the offering of Islamic personal financing among NBFIs in Malaysia, the challenges and the way forward.
Teacher–community nexus and rural schools as community knowledge hubs: a program implementation in Western Nigeria
Authors: Olayinka Sakirat , Deniran Edward Maxwell 
Published: August 2024

PurposeThis study explores a program to transform rural schools in Kwara State, Western Nigeria, into community knowledge hubs by leveraging local networks and community-based workshops. It aims to demonstrate how local resources are utilized to enhance educational outcomes and community engagement in rural settings.Design/methodology/approachEmploying a qualitative research methodology, the study analyzes the implementation of this program through interviews with 13 teachers and in-field participation, examining the perspective of local teachers.FindingsThe findings reveal that this program has significantly enriched community engagement with practical skills both for students and the adult population, fostering collaboration between community and schools. Local teachers, leveraging their rural networks and knowledge, have been central to mobilizing networks and integrating practical education that addresses community-specific issues.Research limitations/implicationsThe critical role of participatory educational strategies is highlighted, designing interventions for the distinct needs of communities. It notes the variability in potential outcomes due to the self-designed networks by local teachers, suggesting a need for exploration into how these networks’ configurations are developed in different places.Practical implicationsThis study advocates for the creation of comprehensive programs including all local stakeholders in developing a dedicated support community network. It emphasizes non-formal education to offer a variety of learning experiences, which may be more effective in fostering community-wide educational engagement.Originality/valueThis study contributes to the academic literature by highlighting the critical role of local networks in African rural education settings. It provides a novel perspective on how rural schools can serve as hubs for community development and lifelong learning for the whole community, extending beyond traditional educational outcomes only for students.