bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Prospective Study of Strut versus Miniplate for Fractures of Mandibular Angle
Authors: Xue Amy S. , Koshy John C. , Wolfswinkel Erik M. , Weathers William M. , Marsack Kristina P. , Hollier Larry H. 
Published: June 2013

This prospective randomized clinical trial compared the treatment outcomes of strut plate and Champy miniplate in fixation of mandibular angle fractures. Patients with mandibular angle fracture were consented and enrolled into this study. Exclusion criteria include patients with severely comminuted fractures. The patients were randomly assigned to receive the strut plate or Champy miniplate for angle fracture fixation. Patient demographics, fracture characteristics, operative and postoperative outcomes were collected prospectively. Statistical analysis was performed to evaluate the significance of the outcome. A total of 18 patients were included in this study and randomly assigned to receive either the strut plate or Champy miniplate. Out of which five patients were excluded postoperatively due to complex fracture resulting in postoperative maxillomandibular fixation. The final enrollment was 13 patients, N = 6 (strut) and N = 7 (Champy). There was no statistically significant difference in the pretreatment variables. Nine of these patients had other associated facial fractures, including parasymphyseal and subcondylar fractures. Most of the (11) patients had sufficient follow-up after surgery. Both groups exhibited successful clinical unions of the mandibular angle fractures. The complications associated with the mandibular angle were 20% in the strut plate group and 16.7% in the Champy group. One patient in the strut plate group had a parasymphyseal infection, requiring hardware removal. The strut plate demonstrated comparable surgical outcome as the Champy miniplate. It is a safe and effective alternative for management of mandibular angle fracture.
Dibenzylammonium hydrogen maleate and a redetermination at 120 K of bis(dibenzylamino)methane
Authors: Castillo Juan C. , Abonía Rodrigo , Cobo Justo , Glidewell Christopher 
Published: June 2013

In dibenzylammonium hydrogen maleate [or dibenzylammonium (2Z)-3-carboxyprop-2-enoate], C14H16N+·C4H3O4−, (I), the anion contains a fairly short and nearly linear O—H...O hydrogen bond, with an O...·O distance of 2.4603 (16) Å, but with the H atom clearly offset from the mid-point of the O...O vector. The counter-ions in (I) are linked by two N—H...O hydrogen bonds to formC22(6) chains and these chains are weakly linked into sheets by a C—H...O hydrogen bond. Bis(dibenzylamino)methane, C29H30N2, (II), crystallizes with two independent molecules lying across twofold rotation axes in the space groupC2/c, and the molecules are conformationally chiral; there are no direction-specific intermolecular interactions in the crystal structure of (II).
Localization of sensory mechanisms utilized by coral planulae to detect settlement cues
Authors: Tran Cawa , Hadfield Michael G. 
Published: June 2013

AbstractCoral planulae are induced to settle and metamorphose by contact with either crustose coralline algae or marine bacterial biofilms. Larvae of two coral species, Pocillopora damicornis and Montipora capitata, which respond to different metamorphic cues, were utilized to investigate the sensory mechanisms used to detect metamorphic cues. Because the aboral pole of the coral planula is the point of attachment to the substratum, we predicted that it is also the point of detection for cues. To determine where sensory cells for cues are localized along the body, individual larvae were transversely cut into oral and aboral portions at various levels along the oral–aboral axis, and exposed to settlement‐inducing substrata. Aboral ends of M. capitata metamorphosed, while oral ends continued to swim. However, in larvae of P. damicornis, ¾ oral ends (i.e., lacking the aboral pole) were also able to metamorphose, indicating that the cells that detect cues may be distributed along the sides of the body. These cells do not correspond to FMRFamide‐immunoreactive cells that are present throughout the body. Cesium ions induced both aboral and oral ends of larvae of both species to settle, suggesting that oral ends have not lost their capacity to metamorphose, despite lacking sensory cells to detect natural cues. To determine whether sensory cells in larvae of P. damicornis are restricted to one side of the body, swimming behavior over substrata was observed in larvae labeled with diI, a red fluorescent lipophilic membrane stain. The larvae were found to rotate around the oral–aboral axis, with their surface against the substratum, not favoring a particular side for detecting cues. While clarifying the regions of the larval body important for settlement and metamorphosis in coral planulae, we conclude that significant differences between coral species may be due to differences in the distribution of sensory structures in relation to different planular sizes.
Flexibility in change practices and job outcomes for nurses: exploring the role of subjective fit
Authors: Newton Cameron , Teo Stephen T.T. , Pick David , Yeung Melissa , Salamonson Yenna 
Published: June 2013

AbstractAimsTo integrate existing theoretical perspectives on change management, subjective fit and occupational stress to better understand the effects of change on employee adjustment.BackgroundAlthough subjective fit with organizational goals and objectives has been shown to have positive effects on employee adjustment, its role in the organizational change–occupational stress context is not understood. This represents a caveat in research when considering the notion that those who feel that they fit with the organization's goals may be better equipped to reconcile and deal with change.DesignA cross‐sectional survey of nurses from public and non‐profit sector hospitals was conducted.MethodData were collected from 252 public and non‐profit sector nurses via online surveys. Data were collected from June–October in 2010. Structural equation modelling was used to test the direct and indirect effects among the focal variables.ResultsThe results showed that public and non‐profit nurses experience flexibility‐limiting and flexibility‐promoting change initiatives and that these are differentially related to the perception of administrative stressors and adjustment with these relationships directly and indirectly influenced by perceptions of subjective fit. Flexibility‐limiting change initiatives led to lower levels of subjective fit, higher levels of administrative stressors and less favourable adjustment. On the other hand, flexibility‐promoting change practices led to higher levels of subjective fit, lower levels of administrative stressors and ultimately better adjustment.ConclusionThe results further the theoretical understanding of the role of subjective fit in organizational change and occupational stress theories.
Ethnic Differences in Quality of Life in Insured Older Adults with Diabetes Mellitus in an Integrated Delivery System
Authors: Laiteerapong Neda , Karter Andrew J. , John Priya M. , Schillinger Dean , Moffet Howard H. , Liu Jennifer Y. , Adler Nancy , Chin Marshall H. , Huang Elbert S. 
Published: June 2013

ObjectivesTo explore racial and ethnic (ethnic hereafter) differences in health‐related quality of life (HRQL) in older adults with diabetes mellitus in an integrated delivery system.DesignObservational cross‐sectional study.SettingKaiser Permanente Northern California.ParticipantsEthnic‐stratified, random sample of 6,096 adults with diabetes mellitus aged 60 to 75 who completed a HRQL questionnaire.MeasurementsPhysical and mental HRQL were measured based on the Medical Outcomes Study 8‐item Short Form Survey (range 0–100, mean 50). Age‐ and sex‐adjusted weighted linear regression models estimated associations between ethnicity and HRQL and evaluated potential mediators (socioeconomic status, acculturation, health behaviors, diabetes mellitus–related conditions). Differences in ethnic‐specific, adjusted mean HRQL scores were tested (reference whites).ResultsPhysical HRQL was better for Filipinos (48.3, 95% confidence interval (CI) = 47.0–49.6, P < .001), Asians (48.1, 95% CI = 46.8–49.3, P < .001), Hispanics (45.1, 95% CI = 44.2–46.0, P < .001), and blacks (44.2, 95% CI = 43.3–45.1, P = .04) than whites (42.9, 95% CI = 42.6–43.2). Adjusting for potential mediators did not change these relationships. Mental HRQL was better only for Asians (52.7, 95% CI = 51.6–53.7, P = .01) than for whites (51.0, 95% CI = 50.7–51.3), but this difference was small and became nonsignificant after adjustment for socioeconomic status, acculturation, health behaviors, and diabetes mellitus–related conditions.ConclusionIn older adults with diabetes mellitus in a well‐established integrated healthcare delivery system, ethnic minorities had better physical HRQL than whites. Equal access to care in an integrated delivery system may hold promise for reducing health disparities in diabetes mellitus‐related patient‐reported outcomes.
The professional competence profile of Finnish nurses practising in a forensic setting
Authors: Koskinen L. , Likitalo H. , Aho J. , Vuorio O. , Meretoja R. 
Published: June 2013

Accessible summary
Forensic nurses in Finland work in the two state‐maintained forensic hospitals. The main function of these hospitals is to perform forensic psychiatric evaluation and provide treatment for two groups of patients: violent offenders found not guilty by reason of insanity, and those too dangerous or difficult to be treated in regional hospitals. Although the forensic nurses work with the most challenging psychiatric patients, they do not have any preparatory special education for the work.
This paper describes the development of nurses who participated in a 1‐year further education programme that was tailored to them.
The nurses experienced that the 1‐year education had a significant impact on their overall competence level. They found that their skills for observing, helping, teaching and caring for their patients had increased during the education.
Conversely, it was found that the nurses collaborated little with their patients' family members. They were also not familiar with utilizing research findings in improving their care of patients.
AbstractForensic nursing is a global and relatively young profession that combines nursing care and juridical processes. There are, however, significant differences in the qualifications of forensic nurses internationally. The aim of the study was to describe the professional competence profile of practising forensic nurses in Finland and to explore the effects of a 1‐year further education programme on that competence profile. The data were collected in 2011–2012 using the Nurse Competence Scale comprising seven competence categories, and analysed using the software package SPSS version 19.0 (SPSS, Inc., Armonk, NY, USA). The participants were 19 forensic nurses and their 15 head nurses. The assessed overall scores from both informant groups indicated a high level of competence across the seven categories. The nurses felt that the overall competence level had increased during the education programme. The increase seen by the head nurses was smaller. The less frequent competence items included utilization of research and involvement of family in care. It can be stated that the 1‐year further education programme was effective in developing the nurses' competence profile and, in particular, affected their professional self‐confidence. It will, however, be essential to strengthen their skills for working with families and their awareness of evidence‐based forensic nursing.
Coencapsulation of Butyl‐Methoxydibenzoylmethane and Octocrylene into Lipid Nanocarriers: UV Performance, Photostability and in vitro Release
Authors: Niculae Gabriela , Badea Nicoleta , Meghea Aurelia , Oprea Ovidiu , Lacatusu Ioana 
Published: June 2013

AbstractThe coencapsulation of two UV filters, butyl‐methoxydibenzoylmethane (BMDBM) and octocrylene (OCT), into lipid nanocarriers was explored to develop stable cosmetic formulations with broad‐spectrum photoprotection and slow release properties. Different types of nanocarriers in various concentrations of the two UV filters were tested to find the combination with the best absorption and release properties. Solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) have been the two types of lipid nanocarriers used. The NLCs were based on either medium chain triglycerides (MCT) or squalene (Sq). The following physicochemical properties of the nanocarriers have been evaluated: particle size, morphology, zeta potential (ZP), entrapment efficiency, loading capacity, and thermal behavior. The nanocarriers have been formulated into creams containing low amounts of UV filters (2.5% BMDBM and 1% OCT). The best photoprotection results were obtained with the cream based on NLCs prepared with MCT, having a sun protection factor (SPF) of 17.2 and an erythemal UVA protection factor (EUVA–PF) of 50.8. The photostability of the encapsulated BMDBM filter was confirmed by subjecting the nanocarriers‐based creams to in vitro irradiation. The prolonged UV‐protection efficacy was coupled with a slow in vitro release of the synthetic UV filters, which followed the Higuchi release model.
Development of a Probabilistic Convective Weather Forecast Threshold Parameter for Flight-Routing Decisions
Authors: Sheth Kapil , Amis Thomas , Gutierrez-Nolasco Sebastian , Sridhar Banavar , Mulfinger Daniel 
Published: June 2013

Abstract
This paper presents a method for determining a threshold value of probabilistic convective weather forecast data. By synchronizing air traffic data and an experimental probabilistic convective weather forecast product, it was observed that aircraft avoid areas of specific forecasted probability. Both intensity and echo top of the forecasted weather were synchronized with air traffic data to derive the probability threshold parameter. This value can be used by dispatchers for flight planning and by air traffic managers to reroute streams of aircraft around convective cells. The main contribution of this paper is to provide a method to compute the probability threshold parameters using a specific experimental probabilistic convective forecast product providing hourly guidance up to 6 h. Air traffic and weather data for a 4-month period during the summer of 2007 were used to compute the parameters for the continental United States. The results are shown for different altitudes, times of day, aircraft types, and airspace users. Threshold values for each of the 20 Air Route Traffic Control Centers were also computed. Additional details are presented for seven high-altitude sectors in the Fort Worth, Texas, center. For the analysis reported here, flight intent was not considered and no assessment of flight deviation was conducted since only aircraft tracks were used.
De l’intérêt de mobiliser en marketing le genre multifactoriel et sa mesure
Authors: Ulrich Isabelle , Tissier-Desbordes Elisabeth 
Published: June 2013

Résumé Cet article souligne l’intérêt du genre et de sa mesure pour éclairer les problématiques marketing. Les auteurs montrent que la mesure du genre a évolué vers une approche multifactorielle comprenant trois facteurs principaux : cognitif (dont l’identité de genre), affectif et comportemental. Le genre apporte une valeur explicative complémentaire au sexe, de préférence quand la mesure est multifactorielle. Les auteurs explicitent également quand et comment utiliser le genre et sa mesure, identifiant les situations dans lesquelles il est pertinent d’employer ce concept, en distinguant contextes biologiques, sociaux, culturels et situationnels.
The epidemiology of hepatitis C virus in Egypt: a systematic review and data synthesis
Authors: Mohamoud Yousra A , Mumtaz Ghina R , Riome Suzanne , Miller DeWolfe , Abu-Raddad Laith J 
Published: June 2013

Abstract

Background
Egypt has the highest prevalence of hepatitis C virus (HCV) in the world, estimated nationally at 14.7%. Our study’s objective was to delineate the evidence on the epidemiology of HCV infection among the different population groups in Egypt, and to draw analytical inferences about the nature of HCV transmission in this country.

Methods
We conducted a systematic review of all data on HCV prevalence and incidence in Egypt following PRISMA guidelines. The main sources of data included PubMed and Embase databases. We also used a multivariate regression model to infer the temporal trend of HCV prevalence among the general population and high risk population in Egypt.

Results
We identified 150 relevant records, four of which were incidence studies. HCV incidence ranged from 0.8 to 6.8 per 1,000 person-years. Overall, HCV prevalence among pregnant women ranged between 5-15%, among blood donors between 5-25%, and among other general population groups between 0-40%. HCV prevalence among multi-transfused patients ranged between 10-55%, among dialysis patients between 50-90%, and among other high risk populations between 10% and 85%. HCV prevalence varied widely among other clinical populations and populations at intermediate risk. Risk factors appear to be parenteral anti-schistosomal therapy, injections, transfusions, and surgical procedures, among others. Results of our time trend analysis suggest that there is no evidence of a statistically significant decline in HCV prevalence over time in both the general population (p-value: 0.215) and high risk population (p-value: 0.426).

Conclusions
Egypt is confronted with an HCV disease burden of historical proportions that distinguishes this nation from others. A massive HCV epidemic at the national level must have occurred with substantial transmission still ongoing today. HCV prevention in Egypt must become a national priority. Policymakers, and public health and medical care stakeholders need to introduce and implement further prevention measures targeting the routes of HCV transmission.
Granulocyte-macrophage colony stimulating factor (GM-CSF) enhances cumulus cell expansion in bovine oocytes
Authors: Peralta Oscar A , Bucher Danai , Fernandez Ana , Berland Marco , Strobel Pablo , Ramirez Alfredo , Ratto Marcelo H , Concha Ilona 
Published: June 2013

Abstract

Background
The objectives of the study were to characterize the expression of the α- and β-subunits of granulocyte-macrophage colony stimulating factor (GM-CSF) receptor in bovine cumulus cells and oocytes and to determine the effect of exogenous GM-CSF on cumulus cells expansion, oocyte maturation, IGF-2 transcript expression and subsequent competence for embryonic development.

Methods
Cumulus-oocyte complexes (COC) were obtained by aspirating follicles 3- to 8-mm in diameter with an 18 G needle connected to a vacuum pump at −50 mmHg. Samples of cumulus cells and oocytes were used to detect GM- CSF receptor by immunofluorescence. A dose–response experiment was performed to estimate the effect of GM-CSF on cumulus cell expansion and nuclear/cytoplasmic maturation. Also, the effect of GM-CSF on IGF-2 expression was evaluated in oocytes and cumulus cells after in vitro maturation by Q-PCR. Finally, a batch of COC was randomly assigned to in vitro maturation media consisting of: 1) synthetic oviductal fluid (SOF, n = 212); 2) synthetic oviductal fluid supplemented with 100 ng/ml of GM-CSF (SOF + GM-CSF, n = 224) or 3) tissue culture medium (TCM 199, n = 216) and then subsequently in vitro fertilized and cultured for 9 days.

Results
Immunoreactivity for both α and β GM-CSF receptors was localized in the cytoplasm of both cumulus cells and oocytes. Oocytes in vitro matured either with 10 or 100 ng/ml of GM-CSF presented a higher (P < 0.05) cumulus cells expansion than that of the control group (0 ng/ml of GM-CSF). GM-CSF did not affect the proportion of oocytes in metaphase II, cortical granules dispersion and IGF-2 expression. COC exposed to 100 ng/ml of GM-CSF during maturation did not display significant differences in terms of embryo cleavage rate (50.4% vs. 57.5%), blastocyst development at day 7 (31.9% vs. 28.7%) and at day 9 (17.4% vs. 17.9%) compared to untreated control (SOF alone, P = 0.2).

Conclusions
GM-CSF enhanced cumulus cell expansion of in vitro matured bovine COC. However, GM-CSF did not increase oocyte nuclear or cytoplasmic maturation rates, IGF-2 expression or subsequent embryonic development.
Characterization of corneal stromal stem cells with the potential for epithelial transdifferentiation
Authors: Hashmani Khurram , Branch Matthew James , Sidney Laura Elizabeth , Dhillon Permesh Singh , Verma Megha , McIntosh Owen Douglas , Hopkinson Andrew , Dua Harminder Singh 
Published: June 2013

Abstract
Introduction
The corneal stroma is being increasingly recognized as a repository for stem cells. Like the limbal and endothelial niches, stromal stem cells often reside in the peripheral cornea and limbus. These peripheral and limbal corneal stromal cells (PLCSCs) are known to produce mesenchymal stem cells in vitro. Recently, a common corneal stromal and epithelial progenitor was hinted at. This study aims to examine the stem cell potential of corneal stromal cells and to investigate their epithelial transdifferentiation ability.

Methods
PLCSCs were grown in traditional Dulbecco modified Eagle medium (DMEM)-based keratocyte culture medium and an M199-based medium and analyzed for a profile of cell-surface markers by using flow cytometry and differentiated into mesenchymal phenotypes analyzed with quantitative polymerase chain reaction (qPCR) and histologic staining. PLCSCs in M199 were subsequently divided into subpopulations based on CD34 and CD105 expression by using fluorescence- activated cell sorting (FACS). Subpopulations were characterized by marker profile and mesenchymal differentiation ability. Both whole PLCSCs and subpopulations were also cultured for epithelial transdifferentiation.

Results
Cells cultured in M199 demonstrated a more stem-like cell-surface marker profile, and the keratocyte marker CD34 was retained for several passages but absent in cells cultured in DMEM. Cells cultured in M199 also exhibited a greater mesenchymal differentiation potential, compared with DMEM. PLCSCs could be divided into CD34+CD105+, CD34-CD105+, and CD34-CD105- subpopulations, of which CD34+CD105+ cells were the most stemlike with regard to marker expression and mesenchymal differentiation potential. Subpopulations of PLCSCs exhibited differing abilities to transdifferentiate into epithelial phenotypes. Cells that were initially CD34+CD105+ showed the greatest differentiation potential, producing CK3+ and CK19+ cells, and expressed a range of both epithelial progenitor (HES1, FRZB1, DCT, SOD2, ABCG2, CDH1, KRT19) and terminally differentiated (DSG3, KRT3, KRT12, KRT24) genes.

Conclusions
Culture medium has a significant effect on the phenotype and differentiation capacity of PLCSCs. The stroma contains a heterogeneous cell population in which we have identified CD34+ cells as a stem cell population with a capacity for mesenchymal and epithelial differentiation.
MATURITY MODELS FOR AGILE PROJECT MANAGEMENT
Authors: Малинина  , Malinina Mariya 
Published: June 2013

Agile methodologies are widely introduced in project management
though their implementation is often eliminated to separate practices
and tools application. A system approach to the maturity development
requires special tools which consider IT projects execution peculiarities.
Maturity models are the assessment and development tool which provide
a company with an opportunity to improve its project management
and environment. In the present article the author focuses on existing
maturity models both in traditional and agile project management.