bluuebunny/crossref_metadata_2025_split huggingface dataset:
Chemical and thermal evaluation of olive oil refining at different oxidative levels
Authors: Caponio Francesco , Chiavaro Emma , Paradiso Vito Michele , Paciulli Maria , Summo Carmine , Cerretani Lorenzo , Gomes Tommaso 
Published: July 2013

In this work, differential scanning calorimetry (DSC) was for the first time applied to evaluate cooling and heating curves and related thermal properties of olive oil during refining process steps starting from two series of samples at different initial peroxide values (low, 15 meq O2/kg and high, 30 meq O2/kg). Thermal properties were statistically correlated by means of principal component analysis (PCA) to those substance classes (products deriving from oxidation, polymerization and hydrolysis of triacylglycerols (TAG)) that could exert adverse effects on consumer health and a negative contribution to the shelf‐life of the refined oil. A concomitant significant increase of K270 and polymerized TAG, as a general decrease of oxidation level was exhibited by oils during bleaching. Crystallization significantly shifted towards lower temperatures as well as onset temperature of heating, enlarging transition range, starting from bleaching and at both oxidation levels. PCA was performed to tentatively discriminate among samples according to different refining steps and/or initial level of oxidation correlating thermal properties and chemical results. The first principal component clearly clustered samples according to different refining steps and this differentiation was possible on the basis of the relation of thermal parameters with polymerized TAG conjugated dienes and trienes (K232 and K270, respectively). This preliminary goal should lead to deepen the study of DSC application in the evaluation of the quality of olive and other vegetable oils during refining.Practical applications: DSC is a thermal technique that nowadays covers a large set of applications in lipid technology due to its indisputable advantages as it does not require sample preparation and use of solvents, resulting in a reduced environmental impact. The preliminary findings of this study promote the application of the technique in the evaluation of olive oil quality during refining steps in relation with molecular species formed as polymerized TAG and conjugated trienes discriminating crude and neutralized samples to bleached and deodorized oils. DSC could be also applied on other vegetable oils where refining process is more frequently applied.
Platinum‐Based Heterogeneously Catalyzed Hydrosilylation
Authors: Pagliaro Mario , Ciriminna Rosaria , Pandarus Valerica , Béland François 
Published: July 2013

AbstractEfficient and recyclable solid catalysts for the hydrosilylation of olefins are highly desirable, both to reduce the economic and environmental costs of traditional homogeneous processes and to improve the health properties of products that find a number of uses in daily life. In this account we critically review selected examples amongst the numerous platinum‐based materials developed in the last decade, with the goal of identifying important challenges in this relevant domain of synthetic organic chemistry.
Sodium Borohydride Reduction of Carbamoyl Azide Function: A Synthesis of N‐Protected N′‐Formyl‐gem‐diaminoalkyl Derivatives
Authors: Verardo Giancarlo , Gorassini Andrea 
Published: July 2013

AbstractA simple, efficient two‐step synthesis of N‐protected N′‐formyl‐gem‐diaminoalkyl derivatives is reported. The procedure involves the unprecedented reduction of the carbamoyl azide of α‐N‐Boc/Fmoc/Z‐protected amino acids and dipeptides (Boc = tert‐butoxycarbonyl, Fmoc = 9‐fluorenylmethoxycarbonyl, Z = benzyloxycarbonyl) by treatment with NaBH4 at room temperature. The reaction proceeds rapidly (45 min) without detectable epimerization (by HPLC‐ESI‐MS analysis) and is not influenced by the nature of the starting carbamoyl azide. The 1H and 13C NMR analyses of the synthesized N‐protected N′‐formamides were carried out in [D6]DMSO. The spectra exhibited the presence of two rotameric forms in solution as a result of the restricted rotation around the N–CO formyl bond. The integration of the N–CH–N protons of the two isomers showed that the cis isomer (rotamer B) was the more abundant conformer by 60 to 78 %. The reported synthesis represents the potential value of carbamoyl azides as versatile chiral starting materials for many synthetic purposes.
Role of leptin in legg–calvé–perthes disease
Authors: Lee Ju‐Hyung , Zhou Lu , Kwon Keun‐Sang , Lee Dongwook , Park Byung‐Hyun , Kim Jung Ryul 
Published: July 2013

ABSTRACTObesity is considered a clinical risk sign for Legg–Calvé–Perthes disease (LCPD). Leptin is primarily secreted by adipocytes, and it regulates adipose tissue mass and body weight. Furthermore, obesity is clearly associated with increased leptin levels. We investigated the roles of leptin and the soluble leptin receptor (sOB‐R) in LCPD. This matched case–control study included 38 male and 3 female patients with LCPD, and an equal number of age—(range was 4–12) and sex‐matched control patients with healthy fractures. Serum leptin and sOB‐R levels were quantified with ELISA. The free leptin index (FLI) was defined as the ratio of leptin to sOB‐R levels. Serum leptin levels, sOB‐R, and FLI were compared between groups. The relationship between leptin, disease severity, and treatment outcomes were analyzed in the LCPD group. There were no significant differences between groups in terms of age, sex, and body mass index (BMI) percentile. Mean leptin levels (p = 0.042), sOB‐R levels (p = 0.003), and FLI (p = 0.013) differed significantly between groups. In the LCPD group, the serum leptin levels, sOB‐R levels, and FLI differed significantly between the lateral pillar and Stulberg classification groups (p < 0.05). Also, the leptin levels and FLI increased significantly according to the lateral pillar and Stulberg classifications even after adjusting for age and BMI percentile (p < 0.05). Circulating leptin and FLI were significantly higher in the LCPD group. Furthermore, leptin, disease severity, and treatment outcomes were associated. This correlation suggests that leptin might play an important role in LCPD pathogenesis. © 2013 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 31:1605‐1610, 2013
Preparation and characterization of nanometer‐thin freestanding polymer foils for laser‐ion acceleration
Authors: Aurand Bastian , Elkin Bentsian , Heim Lars‐Oliver , Lommel Bettina , Kindler Birgit , Tomut Marilena , Rödel Christian , Kuschel Stephan , Jäckel Oliver , Barz Jakob , Kuehl Thomas 
Published: July 2013

ABSTRACTWe report on the production and characterization of polymer‐based ultra‐thin (sub 10 nm) foils suited for experiments on laser‐ion acceleration in the regime of radiation pressure acceleration. Beside the remarkable mechanical stability compared with commonly used diamond‐like‐carbon foils, a very homogeneous layer thickness and a small surface roughness have been achieved. We describe the technical issues of the production process as well as detailed studies of the mechanical stability and surface roughness tests. The capability of producing uniform targets of large area is essential for advanced laser‐ion acceleration projects which are dealing with high repetition rate and extended measurement series, but might also be useful for other applications which require ultra‐thin and freestanding substrates of high quality. © 2013 Wiley Periodicals, Inc. J. Polym. Sci., Part B: Polym. Phys. 2013, 51, 1355–1360
2012 President's Plenary International Psycho‐Oncology Society: future directions in psycho‐oncology
Authors: Breitbart W. , Bultz B. D. , Dunn J. , Grassi L. , Watson M. 
Published: July 2013

AbstractThe inaugural President's Plenary was held at the 2012 International Psycho‐oncology Society's World Congress in Brisbane to provide a platform for dissemination of important initiatives and achievements of interest to cancer professionals globally. The vision of the International Psycho‐oncology Society – clarified and defined in 2004 – is that all cancer patients and their families throughout the world should receive optimal psychosocial care at all stages of disease and survivorship. Recent initiatives have been driven by the need to see psychosocial care available as a seamless part of holistic multidisciplinary quality cancer care and life‐extending lifestyle changes promoted and supported through the expertise of behavioural and social scientists. In keeping with World Health Organization targets that there is ‘no health without mental health’, cancer health must include mental health. This is in line with the patients' declaration to ‘See us – not our disease’. The aim is to ensure that within the next decade, psychosocial care is acknowledged as a vital part of the patient journey and accepted globally as good practice within cancer care. The President's Plenary session covered the need for the following:Behavioural and social scientists to be integral to the planned lifestyle changes that the United Nations agreed, at a high‐level meeting in 2011, to reduce world cancer incidence and morbidity over the next decade;An internationally agreed standard of quality cancer care that includes psychosocial care for patients and their families and carers;An endorsement to assess distress as the 6th vital sign;A declaration that mental health within cancer health is a human right;Psycho‐oncology professionals to integrate into a federation promoting better national and international outcomes; strength in numbers speaking with a unified voice.The aim is to encourage dialogue between all cancer professionals and patient representatives to progress these targets; everyone has a voice. Copyright © 2013 John Wiley & Sons, Ltd.
Magnetic chitosan beads for covalent immobilization of nucleoside 2′-deoxyribosyltransferase: application in nucleoside analogues synthesis
Authors: Fernández-Lucas Jesús , Harris Ruth , Mata-Casar Iria , Heras Angeles , de la Mata Isabel , Arroyo Miguel 
Published: July 2013

Abstract
Cross-linked magnetic chitosan beads were prepared in presence of epichlorohydrin under alkaline conditions, and subsequently incubated with glutaraldehyde in order to obtain an activated support for covalent attachment of nucleoside 2′-deoxyribosyltransferase from Lactobacillus reuteri (LrNDT). Changing the amount of magnetite (Fe3O4) and epichlorohydrin (EPI) led to different macroscopic beads to be used as supports for enzyme immobilization, whose morphology and properties were characterized by scanning electron microscopy, spin electron resonance (ESR), and vibrating sample magnetometry (VSM). Once activated with glutaraldehyde, the best support was chosen after evaluation of immobilization yield and product yield in the synthesis of thymidine from 2′-deoxyuridine and thymine. In addition, optimal conditions for highest activity of immobilized LrNDT on magnetic chitosan were determined by response surface methodology (RSM). Immobilized biocatalyst retained 50 % of its maximal activity after 56.3 h at 60 °C, whereas 100 % activity was observed after storage at 40 °C for 144 h. This novel immobilized biocatalyst has been successfully employed in the enzymatic synthesis of 2′-deoxyribonucleoside analogues as well as arabinosyl-nucleosides such as vidarabine (ara-A) and cytarabine (ara-C). Furthermore, this is the first report which describes the enzymatic synthesis of these arabinosyl-nucleosides catalyzed by an immobilized nucleoside 2′-deoxyribosyltransferase. Finally, the attached enzyme to magnetic chitosan beads could be easily recovered and recycled for 30 consecutive batch reactions with negligible loss of catalytic activity in the synthesis of 2,6-diaminopurine-2′-deoxyriboside and 5-trifluorothymidine.
Traces on cores of -algebras associated with self-similar maps
Authors: KAJIWARA TSUYOSHI , WATATANI YASUO 
Published: July 2013

AbstractWe completely classify the extreme tracial states on the cores of the ${C}^{\ast } $-algebras associated with self-similar maps on compact metric spaces. We present a complete list of them. The extreme tracial states are the union of the discrete type tracial states given by measures supported on the finite orbits of the branch points and a continuous type tracial state given by the Hutchinson measure on the original self-similar set.
Continuation and bifurcation associated to the dynamical spectral sequence
Authors: FRANZOSA R. , DE REZENDE K. A. , DA SILVEIRA M. R. 
Published: July 2013

AbstractIn this paper we consider a filtered chain complex $C$ and its differential given by a connection matrix $\Delta $ which determines an associated spectral sequence $({E}^{r} , {d}^{r} )$. We present an algorithm which sweeps the connection matrix in order to span the modules ${E}^{r} $ in terms of bases of $C$ and gives the differentials ${d}^{r} $. In this process a sequence of similar connection matrices and associated transition matrices are produced. This algebraic procedure can be viewed as a continuation, where the transition matrices give information about the bifurcation behavior. We introduce directed graphs, called flow and bifurcation schematics, that depict bifurcations that could occur if the sequence of connection matrices and transition matrices were realized in a continuation of a Morse decomposition, and we present a dynamic interpretation theorem that provides conditions on a parameterized family of flows under which such a continuation could occur.
Superstable manifolds of invariant circles and codimension-one Böttcher functions
Authors: KASCHNER SCOTT R. , ROEDER ROLAND K. W. 
Published: July 2013

AbstractLet $f: X~\dashrightarrow ~X$ be a dominant meromorphic self-map, where $X$ is a compact, connected complex manifold of dimension $n\gt 1$. Suppose that there is an embedded copy of ${ \mathbb{P} }^{1} $ that is invariant under $f$, with $f$ holomorphic and transversally superattracting with degree $a$ in some neighborhood. Suppose that $f$ restricted to this line is given by $z\mapsto {z}^{b} $, with resulting invariant circle $S$. We prove that if $a\geq b$, then the local stable manifold ${ \mathcal{W} }_{\mathrm{loc} }^{s} (S)$ is real analytic. In fact, we state and prove a suitable localized version that can be useful in wider contexts. We then show that the condition $a\geq b$ cannot be relaxed without adding additional hypotheses by presenting two examples with $a\lt b$ for which ${ \mathcal{W} }_{\mathrm{loc} }^{s} (S)$ is not real analytic in the neighborhood of any point.
Effect of silicon soil amendment on performance of sugarcane borer,Diatraea saccharalis(Lepidoptera:Crambidae) on rice
Authors: Sidhu J.K. , Stout M.J. , Blouin D.C. , Datnoff L.E. 
Published: July 2013

AbstractThe sugarcane borer,Diatraea saccharalis(F.), is a pest of graminaceous crops in the southern USA, including sugarcane, maize, and rice. This study was conducted to investigate the effect of silicon (Si) soil amendments on performance of sugarcane borer,D. saccharalis, on two rice cultivars, Cocodrie and XL723. There was a significant increase in the Si content of rice plants supplemented with calcium silicate as compared to non-treated plants. Soil Si amendment led to lower relative growth rates (RGRs) and reduced boring success of sugarcane borer larvae. Effects of soil Si amendments on borer success and RGR appeared to be more pronounced in ‘Cocodrie’, the cultivar relatively susceptible to borers, than in the moderately resistant cultivar, XL723. Soil Si amendment may contribute to the management ofD. saccharalisthrough reduced feeding injury and increased exposure to adverse environmental conditions and natural enemies arising from reduced boring success.
SEQUENTIAL INTERCROPPING OF COMMON BEAN AND MUNG BEAN WITH MAIZE IN SOUTHERN ETHIOPIA
Authors: WORKU WALELIGN 
Published: July 2013

SUMMARYMost previous studies focused on intercropping systems involving two-crop associations. However, there is much scope to improve existing cropping systems by devising and evaluating modifications that allow more effective use of the season. To this effect, experiments were conducted to quantify efficiency of sequential intercropping consisting of maize (Zea maysL.), common bean (Phaseolus vulgarisL.) and mung bean (Vigna radiata(L.) Wilczek) during 2007 and 2009 cropping seasons, in southern Ethiopia. Treatments included three- and two-crop associations and equivalent sole crops of components. Land equivalent ratio (LER) and area time equivalency ratio (ATER) were used to estimate intercropping advantage. Maize had the highest partialLER, 0.95, whenever mung bean comes first in the sequence. Comparable partialLERs were observed in common bean irrespective of planting times while mung bean had greater partialLERs from simultaneous rather than sequential planting. Maize had the highest competitive ratio (1.56) followed by common bean (0.67) and mung bean (0.53). The three-crop association involving simultaneous planting of maize with mung bean followed by common bean (MZ + MB − CB) gave the highest mean totalLERof 1.66. This combination also had the highest combined productivity and maximum monetary gain, which is above the minimum acceptable marginal rate of return. It exceeded advantages from intercrops of maize–common bean by 41% and maize–mung bean by 23%. Thus, farmers would get greater advantage from practicing sequential intercropping in areas where the season is sufficient to grow long-duration maize.
New species of Cucullanus (Nematoda: Cucullanidae), an intestinal parasite of the peacock bass Cichla piquiti (Perciformes: Cichlidae) from the Tocantins River, Brazil
Authors: Lacerda A.C.F. , Takemoto R.M. , Marchiori N.C. , Martins M.L. , Pavanelli G.C. 
Published: July 2013

AbstractCucullanus tucunarensis n. sp. (Cucullanidae) is described parasitizing the peacock bass Cichla piquiti (Cichlidae) from the Tocantins River, Tocantins State, Brazil. The new species is unique and differs from all its congeners by having a tail tip provided with several sclerotized spine-like processes on its ventral side, present in both the male and female. Furthermore, C. tucunarensis n. sp. is compared with other species of the genus recorded in the same zoogeographical region and in the same group of hosts (Perciformes).
Epidemiology and molecular diversity of rabies viruses in Bulgaria
Authors: ROBARDET E. , ILIEVA D. , ILIEV E. , GAGNEV E. , PICARD-MEYER E. , CLIQUET F. 
Published: July 2013

SUMMARYA health emergency situation occurred in Bulgaria in 2007 when positive rabies cases were notified in Sofia district in the central-western part of the country, suggesting a southward spread of the disease for the first time in the last 10 years. Phylogenetic analysis on 49 isolates sampled between 2009 and 2011 showed, for the first time, evidence of the existence of NEE and D clustered lineages in Bulgaria. Their geographical distribution clearly reveals the permeability of natural barriers, as already suggested by the disease spread that occurred across the Balkan mountain range in 2007. The monitoring and passive surveillance programmes conducted since the first 2009 oral vaccination campaign, the spatio-temporal evolution of the disease in the country since 2007, and the need for further investigation of the role of jackals in virus dispersion are discussed.
Does nutrition information on menus impact food choice? Comparisons across two hospital cafeterias
Authors: Vanderlee Lana , Hammond David 
Published: July 2013

AbstractObjectiveFood prepared and consumed away from home accounts for a significant proportion of dietary intake among Canadians. Currently, Canadians receive little or no nutrition information when eating in restaurant and fast-food outlets. The present study examined the impact of nutrition information on menus in hospital cafeterias on noticing and perceived influence of nutrition information and on food consumption.DesignCross-sectional surveys.SettingExit surveys (n 1003) were conducted in two hospital cafeterias. The ‘intervention’ site featured energy (calorie), sodium and fat content on digital menu boards, as well as a health logo for ‘healthier’ items. The intervention site had also revised its menu items to improve the nutrient profiles. The ‘control’ site provided limited nutrition information at the point of sale.SubjectsCafeteria patrons recruited using the intercept technique.ResultsSignificantly more respondents at the intervention site reported noticing nutrition information (OR = 7·6, P < 0·001) and using nutrition information to select their food items (OR = 3·3, P < 0·001) compared with patrons at the control site, after adjusting for sociodemographic factors. Patrons at the intervention site consumed significantly less energy (−21 %, P < 0·001), sodium (−23 %, P < 0·001), saturated fat (−33 %, P < 0·001) and total fat (−37 %, P < 0·001) than patrons at the control site.ConclusionsA nutritional programme, including nutrition information on menus and improved nutrition profile of food offerings, was associated with substantial reductions in energy, sodium and fat consumption. The results are consistent with a positive impact of menu labelling.
Phosphoproteomics of collagen receptor networks reveals SHP-2 phosphorylation downstream of wild-type DDR2 and its lung cancer mutants
Authors: Iwai Leo K. , Payne Leo S. , Luczynski Maciej T. , Chang Francis , Xu Huifang , Clinton Ryan W. , Paul Angela , Esposito Edward A. , Gridley Scott , Leitinger Birgit , Naegle Kristen M. , Huang Paul H. 
Published: July 2013

Collagen is an important extracellular matrix component that directs many fundamental cellular processes including differentiation, proliferation and motility. The signalling networks driving these processes are propagated by collagen receptors such as the β1 integrins and the DDRs (discoidin domain receptors). To gain an insight into the molecular mechanisms of collagen receptor signalling, we have performed a quantitative analysis of the phosphorylation networks downstream of collagen activation of integrins and DDR2. Temporal analysis over seven time points identified 424 phosphorylated proteins. Distinct DDR2 tyrosine phosphorylation sites displayed unique temporal activation profiles in agreement with in vitro kinase data. Multiple clustering analysis of the phosphoproteomic data revealed several DDR2 candidate downstream signalling nodes, including SHP-2 (Src homology 2 domain-containing protein tyrosine phosphatase 2), NCK1 (non-catalytic region of tyrosine kinase adaptor protein 1), LYN, SHIP-2 [SH2 (Src homology 2)-domain-containing inositol phosphatase 2], PIK3C2A (phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2α) and PLCL2 (phospholipase C-like 2). Biochemical validation showed that SHP-2 tyrosine phosphorylation is dependent on DDR2 kinase activity. Targeted proteomic profiling of a panel of lung SCC (squamous cell carcinoma) DDR2 mutants demonstrated that SHP-2 is tyrosine-phosphorylated by the L63V and G505S mutants. In contrast, the I638F kinase domain mutant exhibited diminished DDR2 and SHP-2 tyrosine phosphorylation levels which have an inverse relationship with clonogenic potential. Taken together, the results of the present study indicate that SHP-2 is a key signalling node downstream of the DDR2 receptor which may have therapeutic implications in a subset of DDR2 mutations recently uncovered in genome-wide lung SCC sequencing screens.
Biology, ecology and management of the South American tomato pinworm, Tuta absoluta.
Authors: Urbaneja A. , Desneux N. , Gabarra R. , Arnó J. , González-Cabrera J. , Mafra Neto A. , Stoltman L. , Pinto A. de S. , Parra J. R. P. 
Published: July 2013

Abstract

This chapter focuses on the South American tomato pinworm Tuta absoluta (i) origin, spread and current distribution; (ii) basic but critical information regarding bioecology; (iii) rearing techniques; (iv) known host plants; (v) sampling and monitoring techniques; and (vi) control methods available from both South America and newly infested areas, as well as their potential use for integrated pest management. Some hints are provided on present and future management strategies.