bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Tetracyclic Triterpenoids Isolated from Semi‐Mangrove Plant Hibiscus titiaceus.
Authors: Cheng Can‐Ling , Wang Zhong‐Zhao , Li Ping‐Lin , Zhang Xing‐Wang , Wu Rong‐Cui , Zhu Hong‐Yan , Tang Xu‐Li , Li Guo‐Qiang 
Published: April 2014

Abstractisolation, structure elucidation and cytotoxicity of two new triterpenoids, tiliacol A (I) and tiliacol B (II), along with one known analogue
ChemInform Abstract: Chiral Resolution Through Stereoselective Transglycosylation by Sucrose Phosphorylase: Application to the Synthesis of a New Biomimetic Compatible Solute, (R)‐2‐O‐α‐D‐Glucopyranosyl Glyceric Acid Amide.
Authors: Wildberger Patricia , Brecker Lothar , Nidetzky Bernd 
Published: April 2014

AbstractThe sucrose phosphorylase catalyzed glycosylation of racemic glyceric acid amide (II) with sucrose (I) affords the new biomimetic glycoside (III) in high yield with complete regio‐ and diastereoselectivity.
ChemInform Abstract: Alkaloids from Ochrosia borbonica.
Authors: Zhang Bing‐Jie , Yan Ju‐Ming , Wu Zi‐Kun , Liu Ya‐Ping , Bao Mei‐Fen , Cheng Gui‐Guang , Luo Xiao‐Dong , Cai Xiang‐Hai , Li Yan 
Published: April 2014

AbstractNext to some known alkaloids from Ochrosia borbonica compound III shows cytotoxic activity against five human cancer cell lines.
ChemInform Abstract: Iriomoteolides‐4a (I) and ‐5a (II), Hydrophilic Macrolides from Marine Dinoflagellate Amphidinium Species.
Authors: Kumagai Keiko , Tsuda Masashi , Fukushi Eri , Kawabata Jun 
Published: April 2014

AbstractThe new macrolides exhibit moderate cytotoxic activity against human B lymphocyte DG‐75 (IC50 0.8 and 1.0 μg/mL, respectively).
ChemInform Abstract: Diospentenols A (I) and B (II), Two New Cyclopentapyrans Isolated from Abandoned Mine Bacterium Streptomyces sp. KMA‐001.
Authors: Park Jin‐Soo , Cha Jin Wook , Kim Seong‐Hwan , Oh Dong‐Chan , Kwon Hak Cheol 
Published: April 2014

AbstractBoth compounds (I) and (II) are obtained as racemic mixtures and their absolute configurations are not determined.
ChemInform Abstract: Synthesis of Flavokawain B and Its anti‐Proliferative Activity Against Gefitinib‐Resistant Non‐Small Cell Lung Cancer (NSCLC).
Authors: Seo Young Ho , Oh Yong Jin 
Published: April 2014

AbstractThe natural product flavokawain B (I) impairs the growth of gefitinib‐resistant non‐small cell lung cancer (H1975) and disrupted Hsp90 chaperoning function.
ChemInform Abstract: A Review on Synthesis and Biological Evaluation of Spiro‐Ketal Derivatives
Authors: Kaur K. , Mehta D. K. , Gupta G. K. , Das R. , Kushwah P. , Farooq S. A. 
Published: April 2014

AbstractReview: methods to synthesize spiro ketals and their pharmacological evaluation from yar 1979 to 2012
Epidermal growth factor‐like domain 7 is a marker of the endothelial lineage and active angiogenesis
Authors: Bambino Kathryn , Lacko Lauretta A. , Hajjar Katherine A. , Stuhlmann Heidi 
Published: April 2014

SummaryEpidermal growth factor‐like domain 7 (Egfl7) expression in the developing embryo is largely restricted to sites of mesodermal progenitors of angioblasts/hemangioblasts and the vascular endothelium. We hypothesize that Egfl7 marks the endothelial lineage during embryonic development, and can be used to define the emergence of endothelial progenitor cells, as well as to visualize newly‐forming vasculature in the embryo and during the processes of physiologic and pathologic angiogenesis in the adult. We have generated a transgenic mouse strain that expresses enhanced green fluorescent protein (eGFP) under the control of a minimal Egfl7 regulatory sequence (Egfl7:eGFP). Expression of the transgene recapitulated that of endogenous Egfl7 at sites of vasculogenesis and angiogenesis in the allantois, yolk sac, and in the embryo proper. The transgene was not expressed in the quiescent endothelium of most adult organs. However, the uterus and ovary, which undergo vascular growth and remodeling throughout the estrus cycle, expressed high levels of Egfl7:eGFP. Importantly, expression of the Egfl7:eGFP transgene was induced in adult neovasculature. We also found that increased Egfl7 expression contributed to pathologic revascularization in the mouse retina. To our knowledge, this is the first mouse model that enables monitoring of endothelial cells at sites of active vasculogenesis and angiogenesis. This model also facilitated the isolation and characterization of EGFL7+ endothelial cell populations by fluorescence activated cell sorting (FACS). Together, our results demonstrate that the Egfl7:eGFP reporter mouse is a valuable tool that can be used to elucidate the mechanisms by which blood vessels form during development and under pathologic circumstances. genesis 52:657–670, 2014. © 2014 Wiley Periodicals, Inc.
Improved Stability of Thin‐Film Multijunction Thermal Converters
Authors: Amaga Yasutaka , Fujiki Hiroyuki , Shimizume Koji , Hidaka Shigeru 
Published: April 2014

SUMMARYWe have demonstrated the long‐term stability and environmental durability of a high‐performance thin‐film multijunction thermal converter (TMJTC) with an improved thin‐film thermopile design. We fabricated a new TMJTC with an improved deposition pattern for a Bi‐Sb‐Cu‐based thin‐film thermopile in order to avoid interface delamination between the Bi and the Cu layers. Our TMJTC exhibited good frequency properties, with an ac–dc difference of less than 5 μV/V in the range from 10 Hz to 100 kHz, at a root‐mean‐square (rms) voltage of 10 V. The long‐term stability of the TMJTC has been significantly increased owing to the performance of the developed thin‐film thermopile, as compared with that of previously fabricated TMJTCs, exhibiting an ac–dc difference of less than 2 μV/V after 18 months at room temperature. We also evaluated the temperature, relative humidity, and pressure characteristics of the TMJTC in accordance with the International Electrotechnical Commission (IEC) standards for electronic devices. The measurement results showed that the dependence of the ac–dc transfer difference on the temperature, humidity, and pressure was less than 1 μV/V, which is comparable to the results of thermal converters, constituting the primary standard.
Suppression of Metallic Particle Lift‐Off in GIS by a Nonlinear Resistivity Coating
Authors: Nojima Kenichi , Zhang Xueqin , Matsuzaki Hidehito , Ando Hideyasu , Shiiki Motoharu , Takei Masafumi 
Published: April 2014

SUMMARYTo suppress metallic particle lift‐off in compact gas‐insulated switchgear (GIS), a coating with nonlinear resistivity characteristics was developed for the inner surface of the GIS tank. An electrical field analysis that measured the current density and electric field (J–E) characteristic indicates that a nonlinear resistivity coating can reduce field intensification at triple junctions between metallic particles and the coating, and can effectively suppress particle lift‐off. The results of experiments using a GIS mock‐up model indicate that a nonlinear resistivity coating increases the lift‐off electric field of metallic particles with less statistical dispersion than a dielectric coating.
Kinetics and Mechanism of the Reduction of mer‐Tris‐picolinatoruthenium(III) by L‐Ascorbic Acid
Authors: Katafias Anna , Impert Olga , Kita Przemysław , Fenska Joanna , Koter Stanisław , Kaczmarek‐Kędziera Anna , Różycki Henryk , Bajek Anna , Uzarska Małgorzata , van Eldik Rudi 
Published: April 2014

AbstractThe kinetics of reduction of the mer‐[RuIII(pic)3] complex (pic– = picolinato) by ascorbic acid (AscH2) leading to formation of a red ruthenium(II) species have been studied spectrophotometrically by using both conventional mixing and stopped‐flow methods. The reaction was followed as a function of the reductant concentration over a wide pH range (1.0–7.4). Electron transfer proceeds by an outer‐sphere mechanism involving three protolytic forms of ascorbic acid, AscH2, AscH– and Asc2–, for which specific rate constants have been determined. The Gibbs' energy of activation was found to correlate linearly with the HOMO energies of the protolytic forms of the reductant. The mer‐[RuIII(pic)3] complex is too sparingly soluble in water to inhibit the growth of the Escherichia coli (ATCC 8739) strain. Its cytotoxicity against non‐tumorigenic cells precludes its potential use as an anticancer agent.
CuII‐Templated Threading of a Bis‐amide‐tris‐amine Macrocycle by Substituted 2,2′‐Bipyridyl Derivatives Assisted by Strong π–π Stacking and Second‐Sphere H‐Bonding Interactions
Authors: Saha Subrata , Santra Saikat , Ghosh Pradyut 
Published: April 2014

AbstractInvited for the cover of this issue is the group of Pradyut Ghosh at the Indian Association for the Cultivation of Science (IACS). The cover image shows the [2]pseudorotaxane architecture in which metal coordination, aromatic π–π stacking, and second‐sphere hydrogen‐bonding interactions operate between the wheel and the axle simultaneously.
Metallic Charge‐Transfer Salts of Bis(ethylenedithio)tetrathiafulvalene with Paramagnetic Tetrachloro(oxalato)rhenate(IV) and Tris(chloranilato)ferrate(III) Anions
Authors: Benmansour Samia , Coronado Eugenio , Giménez‐Saiz Carlos , Gómez‐García Carlos J. , Rößer Carola 
Published: April 2014

AbstractThe synthesis, crystal structure and physical characterization of three radical salts of the donor bis(ethylenedithio)tetrathiafulvalene (BEDT‐TTF or ET) and tetrachloro(oxalato)rhenate(IV) {[ReCl4(C2O4)]2–} or tris(chloranilato)ferrate(III) {[Fe(C6O4Cl2)3]3–} anions are reported. The isolated salts with ReIV are (ET)[ReCl4(C2O4)] [1, monoclinic, space group C2/c with a = 18.3409(3) Å, b = 10.8414(2) Å, c = 11.1285(3) Å, β = 99.9714(7)°, V = 2179.38(8) Å3, Z = 4] and (ET)4[ReCl4(C2O4)]·C6H5CN [2, monoclinic, space group P21/c with a = 11.8549(2) Å, b = 32.9079(5) Å, c = 36.4154(5) Å, β = 96.742(2)°, V = 14108.1(4) Å3, Z = 8]. The salt with FeIII is (ET)6[Fe(C6O4Cl2)3]·(H2O)1.5·(CH2Cl2)0.5 [3, triclinic, space group P$\bar {1}$ with a = 20.9489(7) Å, b = 26.7244(8) Å, c = 33.9132(11) Å, α = 68.262(3)°, β = 80.632(3)°, γ = 71.172(3)°, V = 16672.2(9) Å3, Z = 6]. Compounds 2 and 3 are two rare examples of paramagnetic molecular metals and the first ones in their respective families. Compound 3 has a very unusual θ21 phase and the largest number of independent ET molecules reported to date (18).
Stabilization of refined rapeseed oil during deep‐fat frying by selected herbs*
Authors: Taha Eman , Abouelhawa Salah , El‐Geddawy Mohamed , Sorour Mohamed , Aladedunye Felix , Matthäus Bertrand 
Published: April 2014

Lipophilic components of three herbs, sage, thyme, and rosemary, were extracted into refined rapeseed oil by continuous stirring at 30°C for 24 h. The oxidative and frying stability of the flavored oil was assessed by Rancimat at 120°C and frying of French fries at 175°C, respectively. In comparison to the control with an induction period of 4.1 h in the Rancimat test, the treatment with thyme, rosemary, and sage resulted in induction periods of 5.3, 9.3, and 11.0 h, respectively, corresponding to stabilization factors of 1.1, 2.0, and 2.4, respectively. In contrast to the oxidative stability at 120°C, treated oils exhibited significantly lower frying stability, compared to the control. For instance, whereas rapeseed oils treated with plant materials exceeded the 12% regulatory limit for oligomeric triacylglycerols within 20 h of frying, the limit was only exceeded after 25 h of frying in the control. However, despite the significantly higher level of thermo‐oxidative degradation in the flavored oils, the sensory quality of the French fries prepared in these oils remained still acceptable within the frying time of 32 h whereas fries prepared in the control oil were judged unacceptable. Further, endogenous tocopherols were better protected in the treated oils.Practical applications: The prolongation of the shelf life of frying oils is of great economical and commercial importance. Thus, food processors are very interested in the improvement of the thermal stability of frying oils, which may provide remarkable savings. On the other side more and more flavored oils come to the market. Therefore it is important to have more information about the oxidative and thermal stability of such oils.
Synthesis of 1,2,3‐Triazoles from Azide‐Derivatised Aminocyclitols by Catalytic Diazo Transfer and CuAAC Click Chemistry
Authors: Ji Li , Zhou Guo‐Quan , Qian Chao , Chen Xin‐Zhi 
Published: April 2014

AbstractCuII‐catalysed diazo transfer and CuI‐catalysed azide–alkyne 1,3‐dipolar cycloaddition (CuAAC) “click chemistry” were used to synthesis C7N aminocyclitol‐derivatised 1,2,3‐triazoles. In the course of this work, the ‐N=N‐ moiety was transferred onto C7N aminocyclitols such as validamine, valienamine and valiolamine by employing imidazole‐1‐sulfonyl azide as the diazo transfer reagent with catalysis by CuII, ZnII and NiII, in moderate to good yields. The obtained azidocyclitols were coupled with various terminal alkynes under modified Meldal's conditions with good to excellent yields. The stereo‐ and regiochemistry of the products were confirmed by 2D‐NMR (NOESY and HMBC). One‐pot syntheses of the corresponding 1,2,3‐triazoles, as safer and more efficient procedures, were also investigated and gave moderate to good yields.
Solvent‐Free Buchwald–Hartwig Reaction of Aryl and Heteroaryl Halides with Secondary Amines
Authors: Topchiy Maxim A. , Asachenko Andrey F. , Nechaev Mikhail S. 
Published: April 2014

AbstractA highly efficient solvent‐free protocol for the Buchwald–Hartwig amination of (hetero)aryl halides by secondary amines was developed. The reaction is mediated by a Pd(OAc)2/RuPhos catalytic system in air. Various (hetero)aryl halides were coupled with diaryl, alkyl–aryl, and dialkylamines in good to excellent yields (51 examples, 50–99 % yield).
Palladium‐Catalyzed Direct Arylation of Polyfluoroarenes with Organosilicon Reagents
Authors: Fan Huixin , Shang Yaping , Su Weiping 
Published: April 2014

AbstractThe palladium‐catalyzed direct arylation of polyfluoroarenes with organosilicon reagents was achieved by establishing general reaction conditions. This protocol was compatible with a broad range of functional groups and offered the desired products in moderate to good yields.
Electricity Capacity Markets: A Primer
Authors: Drom Rick 
Published: April 2014

AbstractSufficient generation facilities (i.e., capacity) must be available whenever electricity is needed to meet a particular region's demand, in order for the nation's electric system to effectively function. Although electricity capacity markets established by regional transmission organizations/independent system operators (RTOs/ISOs) vary widely, these markets are designed, among other things, to (1) maintain reliability, (2) encourage the economic development of new capacity resources, and (3) moderate electricity price swings.
Degradation of CO2 through dielectric barrier discharge microplasma
Authors: Duan Xiaofei , Li Yanping , Ge Wenjie , Wang Baowei 
Published: April 2014

AbstractThe continually increasing use of fossil fuels throughout the world has caused carbon dioxide (CO2) concentration to grow rapidly in the atmosphere. Increasing CO2 emissions are the major cause of global warming, and a number of studies have been done to show the predicted effects of global warming. This paper reported a method of degradation of CO2 through dielectric barrier discharge (DBD) plasma; a microplasma reactor was used to decompose CO2 into carbon monoxide (CO) at normal atmosphere and room temperature. Gas chromatography was used to analyze the compositions of the outlet gases. No carbon deposits were found in this work. A variety of parameters, such as feed flow rate, input power, frequency, discharge gap, and external electrode length were investigated. The effects of these parameters on CO2 conversion were examined. At the same time, the effects of feed flow rate and input power on the energy efficiency were studied. The results indicated that a higher conversion of CO2 can be realized with a lower feed flow rate, a limited higher input power and a lower frequency. However, a higher feed flow rate and a lower input power were beneficial for energy utilization. The discharge gap had a little effect on the conversion of CO2 in microplasma reactor. In this work, the highest conversion of CO2 was 18.0%, and the highest energy efficiency was 3.8%. The DBD microplasma is a promising method for decomposing CO2.© 2014 Society of Chemical Industry and John Wiley & Sons, Ltd
Differential effects of early life stress on hippocampus and amygdala volume as a function of emotional abilities
Authors: Aust Sabine , Stasch Joanna , Jentschke Sebastian , Alkan Härtwig Elif , Koelsch Stefan , Heuser Isabella , Bajbouj Malek 
Published: April 2014

ABSTRACTEarly life stress (ELS) is known to have considerable influence on brain development and affective functioning. Previous studies in clinical populations have shown that hippocampus and amygdala, two central structures of limbic emotion processing circuits, are predominantly affected by early stress exposure. Given the inconsistent findings on ELS‐related effects in healthy populations and the associations of ELS and affective functioning, the question arises which additional emotion‐relevant variables need to be considered to better understand the effects of ELS. We, therefore, investigated the volume of hippocampus and amygdala in 25 high alexithymic (h‐ALEX) and 25 low alexithymic (l‐ALEX) individuals, which were matched with regard to ELS, but significantly differed in their degree of emotional functioning. Volumetric analyses were performed using FSL‐FIRST, a method to automatically segment subcortical structures on T1‐weighted magnetic resonance images. Alexithymia was assessed using the Toronto Alexithymia Scale and Bermond–Vorst Alexithymia Questionnaire. ELS was assessed by Childhood Trauma Questionnaire (CTQ) and Early Trauma Inventory. Our data showed that ELS was negatively associated with right hippocampus volume in h‐ALEX individuals, while there was no such association in the l‐ALEX group. Furthermore, ELS was positively associated with left amygdala volume in l‐ALEX individuals, but not in individuals with high levels of alexithymia. The present study emphasizes a substantial relationship between intrapersonal factors, such as alexithymia and neural alterations related to the experience of ELS. Longitudinal study designs are necessary to pursue the question of how emotional abilities interact with individual adaptations to early stress exposure on the neural level. © 2014 Wiley Periodicals, Inc.
CacyBP/SIP protein is important for the proliferation of human glioma cells
Authors: Shi Hengliang , Gao Yong , Tang Yuan , Wu Yuxuan , Gong Hui , Du Jin , Zheng Bao , Hu Jinxia , Shi Qiong , Yu Rutong 
Published: April 2014

AbstractRecently, calcyclin‐binding protein or Siah‐1‐interacting protein (CacyBP/SIP), a component of a novel ubiquitinylation pathway, could regulate the β‐catenin degradation (Fukushima et al., Immunity 2006, 24, 29 – 39). However, the potential role of CacyBP/SIP itself in human glioma cells has not been clarified. Here, we found that CacyBP/SIP was expressed highly in human glioma tissues. Silencing of CacyBP/SIP by short‐hairpin RNA severely suppressed the proliferation of human glioma cell U251, which was at least partly mediated by downregulation of phospho‐Akt (p‐Akt) and phospho‐β‐catenin (p‐β‐catenin) as well as upregulation of p53 and p21. Furthermore, overexpression of CacyBP/SIP obviously promoted the proliferation of human glioma U251, which exhibited the exactly contrary trend in the expression of p‐Akt, p‐β‐catenin, p53, and p21. Taken together, these findings suggest that CacyBP/SIP plays important roles in the proliferation of human glioma cell which might be involved in the development of human glioma. © 2014 IUBMB Life, 66(4):286–291, 2014
Preliminary efficacy of prize‐based contingency management to increase activity levels in healthy adults
Authors: Washington Wendy Donlin , Banna Kelly M. , Gibson Amanda L. 
Published: April 2014

An estimated 30% of Americans meet the criteria for obesity. Effective, low‐cost interventions to increase physical activity are needed to prevent and treat obesity. In this study, 11 healthy adults wore Fitbit accelerometers for 3 weeks. During the initial baseline, subjects earned prize draws for wearing the Fitbit. During intervention, percentile schedules were used to calculate individual prize‐draw criteria. The final week was a return to baseline. Four subjects increased step counts as a result of the intervention. A bout analysis of interresponse times revealed that subjects increased overall step counts by increasing daily minutes active and within‐bout response rates and decreasing pauses between bouts of activity. Strategies to improve effectiveness are suggested, such as modification of reinforcement probability and amount and identification of the function of periods of inactivity.Podcast
Comparative development and evolution of two lateral line phenotypes in lake malawi cichlids
Authors: Webb Jacqueline F. , Bird Nathan C. , Carter Lauren , Dickson Juleen 
Published: April 2014

ABSTRACTCover illustration. The canals of the mechanosensory lateral line system of bony fishes vary in morphology among species, but are contained within a conserved subset of dermatocranial bones. In this issue of the Journal of Morphology, Webb et al. (pp. 678–692 10.1002/jmor.20247) investigate the role of heterochrony in the evolution of widened cranial lateral line canals from narrow canals using a comparative developmental morphological analysis of the lateral line canals in three Lake Malawi cichlids, Labeotropheus fuelleborni and Metriaclima zebra (narrow canals) and Aulonocara baenschi (widened canals). The cover image shows a 3‐D reconstruction (volume rendering) of μCT data from Aulonocara baenschi, revealing the large bony pores of the widened canals in the dentary, anguloarticular and preopercular bones.
Exploring temporal hydroclimatic variability in the Niger Basin (1901–2006) using observed and gridded data
Authors: Tarhule Aondover , Zume Joseph T. , Grijsen Johan , Talbi‐Jordan Amal , Guero Abdou , Dessouassi Robert Y. , Doffou Hilaire , Kone Soungalo , Coulibaly Bréhima , Harshadeep Nagaraja R. 
Published: April 2014

ABSTRACTHydroclimatic variability manifests as abrupt shifts, trends, runs, and recurrent cyclical phenomena, collectively referred to as components. In this article, we tested for the presence and magnitude of each component in the Niger Basin (West Africa), using the 0.5° by 0.5° gridded annual rainfall and temperature data produced by the Climate Research Unit (CRU) at the University of East Anglia, UK, for the period 1901–2006. The streamflow data was also analysed for different sub‐basins of the Niger Basin. Abrupt shifts were tested using a Bayesian and nonparametric approach. Trends were analysed using the Mann‐Kendall trend test. Runs were extracted for dry, neutral, and wet conditions, simulated 1000 times based on the skew normal distribution, and used to investigate various run characteristics. Cyclical behaviour was investigated using continuous wavelet analysis. The results show that an abrupt change point occurred in 1969 in the rainfall and streamflow (but not temperature) time series in all subwatersheds of the Niger Basin. The magnitude of the shift in the mean rainfall varied between 16 and 24%. The temperature time series exhibit strong positive trends in all watersheds. Post change point, the rainfall and streamflow time series show positive, though statistically non‐significant trends at α = 0.1. In contrast, disregarding the change point, all subwatersheds show significant negative trends at α = 0.05 and the maximum run lengths are about 4 years long for both dry and wet conditions. Finally, wavelet analysis showed that both rainfall and streamflow in the Niger Basin fluctuate on cycles that are predominantly 2–4 years long, with a few occurrences in the 6–8 years range. Wavelet activity diminished noticeably when a series appeared strongly dominated by trends. The results provide a more comprehensive view of climatic variability than would be obtained from only one or a few components.