bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analisis Penggunaan Media Peta Berbentuk Puzzle Dari Plastik Kemasan Makanan Ringan Terhadap Kreativitas Siswa
Authors: Elisafira Elisafira , Usmaedi Usmaedi Kent , Ginanjar Ajeng 
Published: July 2024

Masalah yang terdapat dalam penelitian ini yaitu pada proses kegiatan belajar mengajar, karena realita di lapangan saat ini pengajaran di sekolah hanya bersifat monoton. Terpengaruh oleh metode yang hanya menerangkan dengan ceramah. Seorang siswa bisa menikmati pembelajaran jika seorang guru menyajikan materi dengan berbagai metode ketika mengajar di kelas. Hal ini terdapat dua unsur yang penting yaitu metode pengajaran dan media pembelajaran. Kedua unsur ini saling keterkaitan karena dengan metode pengajaran tentunya juga akan mempengaruhi jenis media pembelajaran yang sesuai. Ini bertujuan untuk menghasilkan sebuah karya berupa media peta berbentuk puzzle dengan memanfaatkan plastik kemasan makanan ringan pada mata pelajaran Sejarah. Media peta berbentuk puzzle ini adalah suatu jenis permainan yang dapat merangsang kemampuan logika anak, yang dimainkan dengan cara memasang kembali kepingan puzzle menjadi bentuk yang utuh. Tujuan penelitian ini adalah untuk mengetahui efektifitas penggunaan media peta berbentuk puzzle dalam meningkatkan kreativitas belajar siswa. Metode penelitian yang digunakan adalah penelitian kualitatif. Objek yang diteliti adalah siswa kelas XI MAN 1 Lebak. Teknik pengumpulan data yang digunakan yaitu observasi, wawancara, dokumentasi. Hasil dari penelitian ini adalah Penggunaan media peta berbentuk puzzle dari plastik kemasan makanan ringan terhadap kreativitas siswa pada mata pelajaran Sejarah di kelas XI MAN 1 Lebak ini pada proses pembelajaran sangat menarik siswa dalam mengikuti pelajaran Sejarah, aktif, kreatif serta dapat lebih mudah menghafal posisi-posisi pulau-pulau, Provinsi yang ada di Indonesia.
Tantangan Pariwisata dan Ekonomi Kreatif Provinsi Kepulauan di Sumatera Pasca Pandemi
Authors: Royhan Faradis  , Uswatun Nurul Afifah  
Published: July 2024

Industri pariwisata dan ekonomi kreatif (parekraf) merupakan bentuk transformasi sektor riil dengan prospek masa depan yang baik. Namun demikian penerapan new normal pasca Covid 19 membuat pemulihan sektor ini lebih lambat dibandingkan sektor yang lain terutama di daerah dengan topografi kepulauan. Oleh karena itu pertanyaan penelitian ini adalah melihat bagaimana kinerja sektor parekraf provinsi di Sumatera serta upaya apa yang perlu dilakukan guna menjawab tantangan tersebut. Metode yang digunakan untuk menjawab pertanyaan di atas adalah dengan statistik deskriptif dengan melihat tingkat penghunian kamar sebagai indikator pariwisata terkini. Selain itu, metode analisis cluster juga digunakan dalam penelitian ini untuk menjawab provinsi mana yang membutuhkan prioritas pengembangan industri parekraf. Seluruh sumber data diperoleh dari Publikasi Pariwisata dan Ekonomi Kreatif 2021 dari Kemeparekraf dan Berita Resmi Statistik bulanan dari BPS. Temuan menarik dari penelitian ini adalah baik kinerja pariwisata maupun jumlah industri parekraf pariwisata di provinsi kepualaun lebih rendah dibandingkan dengan provinsi daratan baik secara nasional maupun lingkup Sumatera. Padahal Kepulauan Riau tercatat sebagai provinsi dengan andil industri pariwisata dan ekonomi kreatif terbesar mencapai 5,02 persen terhadap ekonominya dan Kepulauan Bangka Belitung mencapai 2,43 persen di urutan ketiga. Temuan menarik berikutnya adalah produk parekraf dari wilayah kepulauan di Sumatera tidak mendapatkan jangkauan pemasaran yang lebih luas. Alasan infrastruktur transportasi dan cuaca diduga menjadi faktor utama penyebab tantangan ini. Rancangan Undang-undang (RUU) daerah kepulauan harus terus diperjuangkan karena bisa menjadi booster dalam mengurangi kesenjangan pembangunan.
Penerapan Model Pembelajaran Berbasis Salafi Di Era Moderen
Authors: Syahid Nur 
Published: July 2024

Ta'limul muta'allim book is a book that deals with learning methods, learning goals, learning principles, learning strategies, etc. which is generally aimed at instructing a person in morality and ethics. Akhlakul karimah are all good, praiseworthy actions that are deeply ingrained in the human soul and will later become good habits. The purpose of morality is for humans to be virtuous, behave, and treat God and other creatures well, so that humans can become higher and more perfect than other creatures and receive God's blessing. Allah SWT, to finally obtain the happiness of the world. The book taklim is essentially one of the books that explains how one's morality begins in the world of education so that one can gain useful knowledge. At that time, mastering the content of the book Ta'limul Muta'allim will have the effect of forming morality for students right from the learning process. Mastering the ta'limul muta'allim material will enable one to understand what knowledge one should know, the purpose of seeking knowledge from an Islamic perspective, and how one should respect teachers and others
Implementasi Mendidik Anak Dengan Keteladanan Dan Cinta
Authors: Samosir Rotua , Simanungkalit Siska , Silitonga Ester , Gulo Desmawati 
Published: July 2024

Sangat penting bagi orang tua untuk mendidik anak dengan keteladanan dan cinta. Sejak awal, orang tua diharuskan telah memiliki visi dan misi dalam mendidik anak. Karena, jika sampai salah didik, bisa saja timbul suatu permasalahan di kemudian hari. Menurut Catatan Arin, yang harus diingat oleh Anda sebagai orang tua ialah, anak yang dilahirkan ke dunia telah mempunyai predikat sebagai khoiru ummah atau umat terbaik yang mengajak pada kebaikan. Lalu, yang perlu diingat lagi adalah apa yang telah dijelaskan pada QS. An-Nisa (9), “Dan hendaklah takut (kepada Allah) orang-orang yang sekiranya mereka meninggalkan keturunan yang lemah di belakang mereka yang mereka khawatir terhadap kesejahteraannya.”
Formation of a state approach to the accumulation of human potential through the prism of the importance of education
Authors: Gorokhova Svetlana Sergeevna 
Published: July 2024

The subject of the research is a scientifically based concept of human development as the basis for the formation of a socially oriented state policy, as well as the idea of "human capital" derived from it. The paper pays attention to the historical aspects of the formation of the worldview approach under study. The issues of introducing the concept of "human potential" into the economic, political and legal environment of modern states are considered. The factors influencing the progressive development of human potential are investigated, with an emphasis on the role of education in this field in general, and higher education in particular. The article analyzes the specific features of the functioning of the modern educational environment of the Russian Federation, as well as factors influencing the process of integration of education, science and practice in Russia and in the world. Within the framework of the conducted research, the entire complex of formal and logical methods of cognition was used, statistical as well as comparative legal methods were used. The main conclusion of the study is to identify the need, justified by the current situation, for the formation of a new, scientifically based state approach to the accumulation of human potential of our state, formed through the prism of increasing the role of higher education institutions in the formation of both the human potential of the country as a whole and the individual human capital of each individual. The paper notes that higher education institutions, contributing to this capital in the form of high-quality education and scientific research, which is in demand in the realities of the innovative economy, become a key link in the formation of a reliable chain linking the success of the economy, the prosperity of the nation and the well-being of each member of society, which, ultimately, will overcome the existing ones at the present stage difficulties.
Mechanism of action of miR-15a-5p and miR-152-3p in paraquat-induced pulmonary fibrosis through Wnt/β-catenin signaling mediation
Authors: Liu Dong , Guan Yan 
Published: July 2024

Background
miRNAs are small, conserved, single-stranded non-coding RNA that are typically transported by exosomes for their functional roles. The therapeutic potential of exosomal miRNAs has been explored in various diseases including breast cancer, pancreatic cancer, cholangiocarcinoma, skin diseases, Alzheimer’s disease, stroke, and glioma. Pathophysiological processes such as cellular inflammation, apoptosis, necrosis, immune dysfunction, and oxidative stress are closely associated with miRNAs. Internal and external factors such as tissue ischemia, hypoxia, pathogen infection, and endotoxin exposure can trigger these reactions and are linked to miRNAs. Paraquat-induced fibrosis is a protracted process that may not manifest immediately after injury but develops during bodily recovery, providing insights into potential miRNA intervention treatments.

Rationale
These findings could potentially be applied for further pharmaceutical research and clinical therapy of paraquat-induced pulmonary fibrosis, and are likely to be of great interest to clinicians involved in lung fibrosis research.

Methodology
Through a literature review, we identified an association between miR-15a-5p and miR-152-3p and their involvement in the Wnt signaling pathway. This allowed us to deduce the molecular mechanisms underlying regulatory interactions involved in paraquat-induced lung fibrosis.

Results
miR-15a-5p and miR-152-3p play roles in body repair processes, and pulmonary fibrosis can be considered a form of reparative response by the body. Although the initial purpose of fibrotic repair is to restore normal body function, excessive tissue fibrosis, unlike scar formation following external skin trauma, can significantly and adversely affect the body. Modulating the Wnt/β-catenin signaling pathway is beneficial in alleviating tissue fibrosis in various diseases.

Conclusions
In this study, we delineate the association between miR-15a-5p and miR-152-3p and the Wnt/β-catenin signaling pathway, presenting a novel concept for addressing paraquat-induced pulmonary fibrosis.
budC knockout in Klebsiella pneumoniae for bioconversion from glycerol to 1,3‐propanediol
Authors: Guo Xinkun , Fang Huiying , Zhuge Bin , Zong Hong , Song Jian , Zhuge Jian , Du Xingxing 
Published: April 2013

Abstract2,3‐Butanediol (2,3‐BD) is a major by‐product of 1,3‐propanediol (1,3‐PDO) fermentation by Klebsiella pneumoniae ZG25. It not only consumes large amounts of its carbon source and nicotinamide adenine dinucleotide to diminish synthesis of 1,3‐PDO, but also serves as an obstacle to high‐purity 1,3‐PDO in downstream processes. To decrease the formation of 2,3‐BD and make an intrinsic improvement in 1,3‐PDO production, the budC gene in K. pneumoniae, coding 2,3‐BD dehydrogenase, which is a key gene of the 2,3‐BD pathway, was successfully knocked out using the Red recombination system described in this paper. The results of the mutant fed‐batch fermentation showed that the 1,3‐PDO concentration, productivity per cell dry weight, and conversion rate increased to 880 mmol L−1, 22.0 mmol L−1 h−1, and 0.700 mol mol−1, respectively, increasing by 10%, 15%, and 11% compared with the parent strain. Meanwhile, 2,3‐BD was still found in fermentation broth with the 2,3‐BD metabolic pathway blocked, which implies that K. pneumoniae possesses a pathway of the 2,3‐BD cycle as a replenishment pathway.
Investigation of biochemical biorefinery sizing and environmental sustainability impacts for conventional bale system and advanced uniform biomass logistics designs
Authors: Argo Andrew M , Tan Eric CD , Inman Daniel , Langholtz Matt H , Eaton Laurence M , Jacobson Jacob J , Wright Christopher T , Muth David J , Wu May M , Chiu Yi‐Wen , Graham Robin L 
Published: April 2013

AbstractThe 2011 US Billion‐Ton Update1 estimates that there are enough agricultural and forest resources to sustainably provide enough biomass to displace approximately 30% of the country's current petroleum consumption. A portion of these resources are inaccessible at current cost targets with conventional feedstock supply systems because of their remoteness or low yields. Reliable analyses and projections of US biofuels production depend on assumptions about the supply system and biorefinery capacity, which, in turn, depend on economics, feedstock logistics, and sustainability. A cross‐functional team has examined optimal combinations of advances in feedstock supply systems and biorefinery capacities with rigorous design information, improved crop yield and agronomic practices, and improved estimates of sustainable biomass availability. Biochemical‐conversion‐to‐ethanol is analyzed for conventional bale‐based system and advanced uniform‐format feedstock supply system designs. The latter involves ‘pre‐processing’ biomass into a higher‐density, aerobically stable, easily transportable format that can supply large‐scale biorefineries. Feedstock supply costs, logistics and processing costs are analyzed and compared, taking into account environmental sustainability metrics. © 2013 Society of Chemical Industry and John Wiley & Sons Ltd
Considering water availability and wastewater resources in the development of algal bio‐oil
Authors: Chiu Yi‐Wen , Wu May 
Published: April 2013

AbstractThis study aims to quantify water appropriation and the potential production of algal bio‐oil using freshwater and municipal wastewater effluent (MWW) as an alternative water resource. The county‐level analysis focuses on open‐pond algae cultivation systems located in 17 states in the southern United States. Several scenarios were developed to examine the water availability for algae bio‐oil production under various water resource mixing MWW and freshwater. The results of the analysis indicate that water availability can significantly affect the selection of an algal refinery site and therefore the potential production of algal bio‐oil. The production of one liter of algal bio‐oil requires 1036–1666 L of water at the state level, in which 3% to 91% can be displaced by MWW, depending on the biorefinery location. This water requirement corresponds to a total of 25 billion liters of bio‐oil produced if the spatially and temporally available MWW effluent together with 10% of total available freshwater are used. The production of algal bio‐oil is only 14% of estimated production under the assumption that all of the water demand can be fulfilled without any restriction. In addition, if only the spatially and temporally available effluent is used as the sole source of water, the total bio‐oil production is estimated to be 9 billion liters. This study not only quantifies the water demands of the algal bio‐oil, but it also elucidates the importance of taking water sustainability into account in the development of algal bio‐oil. © 2013 Society of Chemical Industry and John Wiley & Sons, Ltd
Constraint‐based strain design using continuous modifications (CosMos) of flux bounds finds new strategies for metabolic engineering
Authors: Cotten Cameron , Reed Jennifer L. 
Published: April 2013

AbstractIn recent years, a growing number of metabolic engineering strain design techniques have employed constraint‐based modeling to determine metabolic and regulatory network changes which are needed to improve chemical production. These methods use systems‐level analysis of metabolism to help guide experimental efforts by identifying deletions, additions, downregulations, and upregulations of metabolic genes that will increase biological production of a desired metabolic product. In this work, we propose a new strain design method with continuous modifications (CosMos) that provides strategies for deletions, downregulations, and upregulations of fluxes that will lead to the production of the desired products. The method is conceptually simple and easy to implement, and can provide additional strategies over current approaches. We found that the method was able to find strain design strategies that required fewer modifications and had larger predicted yields than strategies from previous methods in example and genome‐scale networks. Using CosMos, we identified modification strategies for producing a variety of metabolic products, compared strategies derived from Escherichia coli and Saccharomyces cerevisiae metabolic models, and examined how imperfect implementation may affect experimental outcomes. This study gives a powerful and flexible technique for strain engineering and examines some of the unexpected outcomes that may arise when strategies are implemented experimentally.
Graphene‐Assisted Room‐Temperature Synthesis of 2D Nanostructured Hybrid Electrode Materials: Dramatic Acceleration of the Formation Rate of 2D Metal Oxide Nanoplates Induced by Reduced Graphene Oxide Nanosheets
Authors: Sung Da‐Young , Gunjakar Jayavant L. , Kim Tae Woo , Kim In Young , Lee Yu Ri , Hwang Seong‐Ju 
Published: April 2013

AbstractA new prompt room temperature synthetic route to 2D nanostructured metal oxide–graphene‐hybrid electrode materials can be developed by the application of colloidal reduced graphene oxide (RGO) nanosheets as an efficient reaction accelerator for the synthesis of δ‐MnO2 2D nanoplates. Whereas the synthesis of the 2D nanostructured δ‐MnO2 at room temperature requires treating divalent manganese compounds with persulfate ions for at least 24 h, the addition of RGO nanosheet causes a dramatic shortening of synthesis time to 1 h, underscoring its effectiveness for the promotion of the formation of 2D nanostructured metal oxide. To the best of our knowledge, this is the first example of the accelerated synthesis of 2D nanostructured hybrid material induced by the RGO nanosheets. The observed acceleration of nanoplate formation upon the addition of RGO nanosheets is attributable to the enhancement of the oxidizing power of persulfate ions, the increase of the solubility of precursor MnCO3, and the promoted crystal growth of δ‐MnO2 2D nanoplates. The resulting hybridization between RGO nanosheets and δ‐MnO2 nanoplates is quite powerful not only in increasing the surface area of manganese oxide nanoplate but also in enhancing its electrochemical activity. Of prime importance is that the present δ‐MnO2–RGO nanocomposites show much superior electrode performance over most of 2D nanostructured manganate systems including a similar porous assembly of RGO and layered MnO2 nanosheets. This result underscores that the present RGO‐assisted solution‐based synthesis can provide a prompt and scalable method to produce nanostructured hybrid electrode materials.
The Nature of the UC Double Bond: Pushing the Stability of High‐Oxidation‐State Uranium Carbenes to the Limit
Authors: Cooper Oliver J. , Mills David P. , McMaster Jonathan , Tuna Floriana , McInnes Eric. J. L. , Lewis William , Blake Alexander J. , Liddle Stephen T. 
Published: April 2013

AbstractTreatment of [K(BIPMMesH)] (BIPMMes={C(PPh2NMes)2}2−; Mes=C6H2‐2,4,6‐Me3) with [UCl4(thf)3] (1 equiv) afforded [U(BIPMMesH)(Cl)3(thf)] (1), which generated [U(BIPMMes)(Cl)2(thf)2] (2), following treatment with benzyl potassium. Attempts to oxidise 2 resulted in intractable mixtures, ligand scrambling to give [U(BIPMMes)2] or the formation of [U(BIPMMesH)(O)2(Cl)(thf)] (3). The complex [U(BIPMDipp)(μ‐Cl)4(Li)2(OEt2)(tmeda)] (4) (BIPMDipp={C(PPh2NDipp)2}2−; Dipp=C6H3‐2,6‐iPr2; tmeda=N,N,N′,N′‐tetramethylethylenediamine) was prepared from [Li2(BIPMDipp)(tmeda)] and [UCl4(thf)3] and, following reflux in toluene, could be isolated as [U(BIPMDipp)(Cl)2(thf)2] (5). Treatment of 4 with iodine (0.5 equiv) afforded [U(BIPMDipp)(Cl)2(μ‐Cl)2(Li)(thf)2] (6). Complex 6 resists oxidation, and treating 4 or 5 with N‐oxides gives [{U(BIPMDippH)(O)2‐ (μ‐Cl)2Li(tmeda)] (7) and [{U(BIPMDippH)(O)2(μ‐Cl)}2] (8). Treatment of 4 with tBuOLi (3 equiv) and I2 (1 equiv) gives [U(BIPMDipp)(OtBu)3(I)] (9), which represents an exceptionally rare example of a crystallographically authenticated uranium(VI)–carbon σ bond. Although 9 appears sterically saturated, it decomposes over time to give [U(BIPMDipp)(OtBu)3]. Complex 4 reacts with PhCOtBu and Ph2CO to form [U(BIPMDipp)(μ‐Cl)4(Li)2(tmeda)(OCPhtBu)] (10) and [U(BIPMDipp)(Cl)(μ‐Cl)2(Li)(tmeda)(OCPh2)] (11). In contrast, complex 5 does not react with PhCOtBu and Ph2CO, which we attribute to steric blocking. However, complexes 5 and 6 react with PhCHO to afford (DippNPPh2)2CC(H)Ph (12). Complex 9 does not react with PhCOtBu, Ph2CO or PhCHO; this is attributed to steric blocking. Theoretical calculations have enabled a qualitative bracketing of the extent of covalency in early‐metal carbenes as a function of metal, oxidation state and the number of phosphanyl substituents, revealing modest covalent contributions to UC double bonds.
ChemInform Abstract: The Synthesis and Characterization of LaCa2Fe2GaO8.
Authors: Luo Kun , Hayward Michael A. 
Published: April 2013

AbstractThe title compound is prepared from stoichiometric mixtures of La2O3, SrCO3, Ga2O3, and Fe2O3 (flowing Ar, 1300 °C, 80 h) and characterized by neutron powder diffraction and magnetic measurements.
ChemInform Abstract: Structure and Magnetic Properties of Ba5Ce1.25Mn3.75O15, a New 10H‐Polytype in the Ba—Ce—Mn—O System.
Authors: Macias Mario A. , Mentre Olivier , Colis Silviu , Cuello Gabriel J. , Gauthier Gilles H. 
Published: April 2013

AbstractThe new title compound is synthesized by solid state reaction of a stoichiometric mixture of BaCO3, MnCO3, and CeO2 (air, 1000—1350 °C, 172 h).
ChemInform Abstract: A New Polymorph of Potassium Chromate(III), β‐KCrO2, and Reinvestigation of α‐KCrO2.
Authors: Ali Naveed Zafar , Nuss Juergen , Jansen Martin 
Published: April 2013

AbstractDark green single crystals of β‐KCrO2 are obtained by further annealing of α‐KCrO2 (Ag crucible, 773 K, 200 h) which is synthesized by the azide/nitrate route from stoichiometric mixtures of KN3, KNO3, and Cr2O3 (Ag crucible, 853 K, 5 h).
ChemInform Abstract: Pd2+‐Incorporated Perovskite CaPd3M4O12 (M: Ti, V).
Authors: Shiro Kentaro , Yamada Ikuya , Ikeda Naoya , Ohgushi Kenya , Mizumaki Masaichiro , Takahashi Ryoji , Nishiyama Norimasa , Inoue Toru , Irifune Tetsuo 
Published: April 2013

AbstractNovel A‐site ordered perovskites CaPd3Ti4O12 and CaPd3V4O12 are synthesized (stoichiometric mixture of CaO, PdO, TiO2 or VO2; Au capsule, 15 GPa, 1000°C, 30 min, quenching).
ChemInform Abstract: Design and Synthesis of a C2‐Symmetric Chiral 1,2‐Bis(diphenylphosphino)benzene Ligand via Rhodium‐Catalyzed Intramolecular [2 + 2 + 2] Cycloaddition.
Authors: Mori Fumiya , Noguchi Keiichi , Tanaka Ken 
Published: April 2013

AbstractA novel ligand is prepared and tested in rhodium‐catalyzed asymmetric hydrogenation reactions of alkenes.
ChemInform Abstract: Nickel‐Catalyzed Decyanation of Inert Carbon—Cyano Bonds.
Authors: Patra Tuhin , Agasti Soumitra , Akanksha Akanksha , Mati Debabrata 
Published: April 2013

AbstractA general protocol for the Ni‐catalyzed decyanation of aryl, alkyl, and benzyl nitriles using 1,1,3,3‐tetramethyldisiloxane as a hydride source is elaborated.
ChemInform Abstract: Catalytic Enantioselective O‐Nitrosocarbonyl Aldol Reaction of β‐Dicarbonyl Compounds.
Authors: Baidya Mahiuddin , Griffin Kimberly A. , Yamamoto Hisashi 
Published: April 2013

AbstractThe synthetic value of this protocol is demonstrated by preparation of the antibacterial (S)‐kjellmanianone (XVI).
ChemInform Abstract: Asymmetric Trifluoromethylation of Aromatic Aldehydes by Cooperative Catalysis with (IPr)CuF and Quinidine‐Derived Quaternary Ammonium Salt.
Authors: Wu Shaoxiang , Zeng Wei , Wang Qi , Chen Fu‐Xue 
Published: April 2013

AbstractEnhanced catalytic activity and higher enantioselectivities, compared to the previously published methods, arise from the in situ generation of active [(IPr)CuCF3] species.
ChemInform Abstract: One‐Pot Catalyst‐Free Synthesis of β‐ and γ‐Hydroxy Sulfides Using Diaryliodonium Salts and Microwave Irradiation.
Authors: Vaddula Buchi Reddy , Varma Rajender S. , Leazer John 
Published: April 2013

AbstractThis reaction has a high regioselectivity for the substitution of the primary hydroxy group.