bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reverse Geometry Hybrid Contact Lens Fitting in a Case of Donor-Host Misalignment after Keratoplasty
Authors: Pérez-Cambrodí Rafael J , Ruiz-Fortes Pedro 
Published: October 2013

ABSTRACT

Purpose
To report the successful outcome obtained after fitting a new hybrid contact lens in a cornea with an area of donor-host misalignment and significant levels of irregular astigmatism after penetrating keratoplasty (PKP).

Materials and methods
A 41-year-old female with bilateral asymmetric keratoconus underwent PKP in her left eye due to the advanced status of the disease. One year after surgery, the patient referred a poor visual acuity and quality in this eye. The fitting of different types of rigid gas permeable contact lenses was performed, but with an unsuccessful outcome due to contact lens stability problems and uncomfortable wear. Scheimpflug imaging evaluation revealed that a donor-host misalignment was present at the nasal area. Contact lens fitting with a reverse geometry hybrid contact lens (Clearkone, SynergEyes Carlsbad) was then fitted. Visual, refractive, and ocular aberrometric outcomes were evaluated during a 1-year period after the fitting.

Results
Uncorrected distance visual acuity improved from a prefitting value of 20/200 to a best corrected postfitting value of 20/20. Prefitting manifest refraction was +5.00 sphere and .5.50 cylinder at 75°, with a corrected distance visual acuity of 20/30. Higher order root mean square (RMS) for a 5 mm pupil changed from a prefitting value of 6.83 μm to a postfitting value of 1.57 μm (5 mm pupil). The contact lens wearing was referred as comfortable, with no anterior segment alterations.

Conclusion
The SynergEyes Clearkone contact lens seems to be another potentially useful option for the visual rehabilitation after PKP, especially in cases of donor-host misalignment.

How to cite this article
Pérez-Cambrodí RJ, Ruiz-Fortes P, Llorens DPP. Reverse Geometry Hybrid Contact Lens Fitting in a Case of Donor-Host Misalignment after Keratoplasty. Int J Kerat Ect Cor Dis 2013;2(2):69-72.
Pregnancy-induced Progression of Keratoconus in a 37-Year-Old Patient
Authors: Valbon Bruno Freitas , Glicéria Juliana , Santos Rodrigo Teixeira 
Published: October 2013

ABSTRACT

Purpose
To report a case of keratoconus that progressed during pregnancy without any accompanying disease.

Methods
A case report.

Results
A patient with keratoconus that worsened during pregnancy demonstrates that pregnancy can be a previously unrecognized risk factor for progression of keratoconus.

Conclusion
To our knowledge, this is the first case reported in Brazil and the third paper in the world showing pregnancyinduced keratoconus progression in a patient with no accompanying disease.

How to cite this article
Glicéria J, Valbon BF, Santos RT, Ambrósio R Jr. Pregnancy-induced Progression of Keratoconus in a 37-Year-Old Patient. Int J Kerat Ect Cor Dis 2013;2(2):84-88.
Intacs 210° in Post-lasik Ectasia: Follow-up of Clinical and Biomechanical Changes
Authors: Blanco Claudia , Nuñez Maria Ximena 
Published: October 2013

ABSTRACT
The authors report a case of a post-LASIK corneal ectasia with low refractive defect and progressive decreased visual acuity. INTACS SK 210° arc in 7 central millimeters was implanted, 1 year postoperative showed a decreased in maximum keratometry, vertical coma and improved visual acuity. Two years postoperative topography evidence progression of the ectasia.

How to cite this article
Nuñez MX, Blanco C. Intacs 210° in Post-lasik Ectasia: Follow-up of Clinical and Biomechanical Changes. Int J Kerat Ect Cor Dis 2013;2(2):89-91.
A Phenomenology of Return: Forgiveness and Atonement in Emmanuel Levinas and Abraham Joshua Heschel
Authors: Palmisano, SJ Joseph Redfield 
Published: October 2013

A way of remembering the sanctity of the other may inform and guide Christianity towards a more robust dialogical perspective with others. This essay will widen the question for the Christian community by exploring how Judaism remembers those who have been wronged. The methodology is phenomenological in so far as the essay explores the phenomenon of return (teshuva) through the thought of Emmanuel Levinas in dialogue with Abraham Joshua Heschel. When Christianity regards Judaism as a living tradition, instead of a relic, atonement and forgiveness rises to the broader horizon of being ethically relevant in an interreligious context. The real-time teaching (talmud) from righteousness (tzedakah) in Judaism opens opportunities for dialogue with otherness. This exploration of what forgiveness and atonement may mean in a post-Shoah world for Jews and Christians may only contribute to how dialoguing with otherness is a necessary form of return (teshuva) for all interreligious dialogues.
Leveraging Compatible Iridium(III) Complexes to Boost Performance of Green Solvent‐Processed Non‐Fullerene Organic Solar Cells
Authors: Xia Hao , Zhang Miao , Wang Huaxi , Sun Yingjie , Li Zikang , Ma Ruijie , Liu Heng , Dela Peña Top Archie , Chandran Hrisheekesh Thachoth , Li Mingjie , Wu Jiaying , Lu Xinhui , Wong Wai‐Yeung , Li Gang 
Published: July 2024

AbstractIn organic solar cells (OSCs), the short exciton lifetime poses a significant limitation to exciton diffusion and dissociation. Extending exciton lifetime and suppressing recombination are crucial strategies for improving the OSC performance. Herein, an effective approach is proposed by introducing the phosphorescent emitter, tris(2‐(4‐(tert‐butyl)phenyl)‐5‐fluoropyridine)Iridium(III), with long‐lived triplet exciton lifetime in OSCs. This research reveals that the steric structure of fac‐Ir(tBufppy)3 exhibits excellent compatibility with both the donor PM6 and acceptor BTP‐eC9, maintaining efficiencies of over 90% even with a 30% third component loading. Moreover, a 10% addition of fac‐Ir(tBufppy)3 mitigates excessive aggregation in the acceptor BTP‐eC9, optimizing the active layer morphology and improving the fill factor. Transient absorption spectroscopy and transient photoluminescence measurements demonstrate that the introduction of fac‐Ir(tBufppy)3 significantly extends exciton lifetimes and suppresses recombination, which increases the short‐circuit current (JSC). Ultimately, employing the non‐halogenated solvent o‐xylene for processing, an impressive power conversion efficiency (PCE) of 18.54% is achieved in devices based on PM6:10%fac‐Ir(tBufppy)3:BTP‐eC9, surpassing the efficiency of binary PM6:BTP‐eC9 devices (17.41%). This work provides a promising approach to further improve the PCEs in binary OSCs by introducing a phosphorescent iridium(III) complex as the third component.
Designed Spin‐Texture‐Lattice to Control Anisotropic Magnon Transport in Antiferromagnets
Authors: Meisenheimer Peter , Ramesh Maya , Husain Sajid , Harris Isaac , Park Hyeon Woo , Zhou Shiyu , Taghinejad Hossein , Zhang Hongrui , Martin Lane W. , Analytis James , Stevenson Paul , Íñiguez‐González Jorge , Kim Se Kwon , Schlom Darrell G. , Caretta Lucas , Yao Zhi , Ramesh Ramamoorthy 
Published: July 2024

AbstractSpin waves in magnetic materials are promising information carriers for future computing technologies due to their ultra‐low energy dissipation and long coherence length. Antiferromagnets are strong candidate materials due, in part, to their stability to external fields and larger group velocities. Multiferroic antiferromagnets, such as BiFeO3 (BFO), have an additional degree of freedom stemming from magnetoelectric coupling, allowing for control of the magnetic structure, and thus spin waves, with the electric field. Unfortunately, spin‐wave propagation in BFO is not well understood due to the complexity of the magnetic structure. In this work, long‐range spin transport is explored within an epitaxially engineered, electrically tunable, 1D magnonic crystal. A striking anisotropy is discovered in the spin transport parallel and perpendicular to the 1D crystal axis. Multiscale theory and simulation suggest that this preferential magnon conduction emerges from a combination of a population imbalance in its dispersion, as well as anisotropic structural scattering. This work provides a pathway to electrically reconfigurable magnonic crystals in antiferromagnets.
Positively Charged Hollow Co Nanoshells by Kirkendall Effect Stabilized by Electron Sink for Alkaline Water Dissociation
Authors: Zhang Tao , Hang Lifeng , Liu Qingyi , Tao Shi , Bao Haoming , Fan Hong Jin 
Published: July 2024

AbstractWhile cobalt (Co) exhibits a comparable energy barrier for H* adsorption/desorption to platinum in theory, it is generally not suitable for alkaline hydrogen evolution reaction (HER) because of unfavorable water dissociation. Here, the Kirkendall effect is adopted to fabricate positive‐charged hollow metal Co (PHCo) nanoshells that are stabilized by MoO2 and chainmail carbon as the electron sink. Compared to the zero‐valent Co, the PHCo accelerates the water dissociation and changes the rate‐determining step from Volmer to Heyrovsky process. Alkaline HER occurs with a low overpotential of 59.0 mV at 10 mA cm−2. Operando Raman and first principles calculations reveal that the interfacial water to the PHCo sites and the accelerated proton transfer are conducive to the adsorption and dissociation of H2O molecules. Meanwhile, the upshifted d‐band center of PHCo optimizes the adsorption/desorption of H*. This work provides a unique synthesis of hollow Co nanoshells via the Kirkendall effect and insights to water dissociation on catalyst surfaces with tailored charge states.
Rational Strategies to Improve the Efficiency of 2D Perovskite Solar Cells
Authors: Wu Guangbao , Zhang Runqi , Wang He , Ma Kangjie , Xia Junmin , Lv Wenzhen , Xing Guichuan , Chen Runfeng 
Published: July 2024

AbstractIn the quest for durable photovoltaic devices, 2D halide perovskites have emerged as a focus of extensive research. However, the reduced dimension in structure is accompanied by inferior optical‐electrical properties, such as widened band gap, enhanced exciton binding energy, and obstructed charge transport. As a result, the efficiency of 2D perovskite solar cells (PSCs) lags significantly behind their 3D counterparts. To overcome these constraints, extensive investigations into materials and processing techniques are pursued rigorously to augment the efficiency of 2D PSCs. Herein, The cutting‐edge delve into developments in 2D PSCs, with a focus on chemical and material engineering, as well as their structure and photovoltaic properties. The review starts with an introduction of the crystal structure, followed by the key evaluation criteria of 2D PSCs. Then, the strategies around solution chemical engineering, processing technique, and interface optimization, to simultaneously boost efficiency and stability are systematically discussed. Finally, the challenges and perspectives associated with 2D perovskites to provide insights into potential improvements in photovoltaic performance will be outlined.
A Nanomechanical Transducer for Remote Signal Transmission onto the Tympanic Membrane–Playing Music on a Different Drum
Authors: Scott Shelley A. , Yang Fan , Haugg Stefanie , Bhat Abhishek , Scheer Elke , Zierold Robert , Flack Frank , Lagally Max G. , Blick Robert H. 
Published: July 2024

AbstractThe combination of piezoelectric ceramics with silicon nanomembranes can provide a unique combination of electronic and mechanical functionality. For example, an integrated remotely accessible sensor/actuator can serve as a sound transducer to be placed on the tympanic membrane of the human ear. Such an implant would enable direct sound transmission in the kHz range via down‐conversion of a modulated carrier signal at radio frequency. The viability of this concept is demonstrated via a specific design of the nanomembrane bonded over a hole in the piezoelectric chip as well as driving this chip to create a strong nonlinear mechanical response in the nanomembrane. The response in the audible‐frequency range and the result is demonstrated by modulating the piezoelectric chip with a C‐major audible tune—the tone ladder—and retrieving this sound by an optical readout method. Finally, to prove the possibility of remote actuation of the nanomembrane, an antenna on the chip is integrated and the wide‐band transmission from a mobile source is simulated. It is concluded that a remotely actuated invisible hearing aid is possible.
Magnetotropic Hybrid Generator with Self‐Switching Mechanism for Long‐Term Forest Fire Prevention
Authors: Zheng Changyue , Liang Chuangjian , Wen Honggui , Qu Hang , Ning Heng , Chen Chunjin , Long Siyu , Wan Lingyu , Liu Guanlin , Guo Hengyu 
Published: July 2024

AbstractThe integration of triboelectric nanogenerator (TENG) with electromagnetic generator (EMG) holds promise for the efficient harvesting of broadband wind energy, yet the challenge of coupling these two systems into one high‐durability unit has persisted. Herein, a novel magnetic attraction coupling principle is proposed to enable seamless switching between TENG unit and EMG unit across varying rotation speeds without the need for additional mechanical components, thereby enhancing the energy harvesting efficiency of the magnetotropic hybrid generator (MHG). The rotating magnetic field induces the Si‐Mn steel plates to operate in a contact‐separation mode within a compact space, producing a 270 V open‐circuit voltage output, while the excess magnetic flux is captured by coils to generate an induced current of 5 mA. Most importantly, the overall structure is free from mechanical wear, maintaining consistent performance after 130 000 cycles. The harvested wind energy by MHG is utilized to power human infrared sensors, flame sensors, and Bluetooth hygrometers, providing a long‐term, stable power supply for forest fire early warning systems. This study pioneers a novel and robust mechanism that effectively combines TENG and EMG using magnetotropic property, opening a new avenue for efficiently harvesting wide‐band mechanical energy.
Total Synthesis of (−)‐Daphenylline by Gold‐Catalyzed Intramolecular Dearomatization Reaction of Methoxynaphthalene
Authors: Cao Meng‐Yue , Gu Qing‐Xiu , Long Jinguo , Fang Xianjie , Lu Hai‐Hua 
Published: July 2024

AbstractDaphenylline, a structurally unique triterpenoid Daphniphyllum alkaloid, has attracted considerable attention from the synthetic community since its isolation. Herein, we delineate an enantioselective total synthesis of (−)‐daphenylline, which is based on a gold‐catalyzed dearomatization reaction of β‐methoxynaphthalene. Other features include installation of the initial chiral stereocenter via an enantioselective rhodium‐catalyzed hydrogenation of an alkylidene‐indane derivative; construction of the other vital stereocenter by organocatalytic asymmetric Mukaiyama–Michael reaction of a structurally complex benzofused cyclohexanone; and a tandem reductive amination/amidation double cyclization reaction to assemble the distinctive azapolycyclic cage‐like architecture.
RNA Encapsulation in Metal–Organic Frameworks for Targeting Cancer‐Causing Genes
Authors: Mishra Meemansha , Dey Tapan , Mishra Mallya , Chauhan Isha , Dutta Saikat 
Published: July 2024

AbstractA rapid emergence of small interfering ribonucleic acid (siRNA) is witnessed as a powerful tool in gene therapy for suppressing gene expression. Since highly porous metal‐organic frameworks (MOFs) are fragile and inefficient with non‐specific gene delivery techniques, developing strategies use them to encapsulate unmodified natural siRNA from enzymatic degradation. MOFs with high nucleic acid binding affinity are ideal for encapsulating siRNAs in cancer therapy, bypassing circulation time and non‐specificity. To knock down Plk1gene, tumor cell membranes can hide Plk1 siRNA‐containing (Zeolitic Imidazolate framework) ZIF‐8 nanoparticles. For tumor suppression MOF‐promoted lysosome siRNA release, cell membrane coating, and PLK1 silencing are employed. Lysosomes attack cancer by delivering miRNA to targeted cells. Single‐stranded miRNA, two‐stranded siRNA. Despite their different sources, structures, modes of action, and biological activities, miRNA and siRNA regulate gene expression. SIRNA blocks genes more accurately than miRNA, which regulates larger genes. SiRNA‐MOF integration in vitro results in a maximum of 27% consistent gene silencing during endocytic absorption. Cofactor‐encapsulated MOF‐internalized siRNA kills enzymes. A universal siRNA delivery for a specific genetic sequence with personalized therapeutic potential contrasts with multi‐route cancer drugs. SiRNAs cleave long‐stranded RNAs coding for specific genes, allowing biocompatible MOFs to encapsulate macromolecules and protect them from injury.
A Linkable, Polycarbonate Gut Microbiome‐Distal Tumor Chip Platform for Interrogating Cancer Promoting Mechanisms
Authors: Brasino Danielle S.K. , Speese Sean D. , Schilling Kevin , Schutt Carolyn E. , Barton Michelle C. 
Published: July 2024

AbstractGut microbiome composition is tied to diseases ranging from arthritis to cancer to depression. However, mechanisms of action are poorly understood, limiting development of relevant therapeutics. Organ‐on‐chip platforms, which model minimal functional units of tissues and can tightly control communication between them, are ideal platforms to study these relationships. Many gut microbiome models are published to date but devices are typically fabricated using oxygen permeable polydimethylsiloxane, requiring interventions to support anaerobic bacteria. To address this challenge, a platform is developed where the chips are fabricated entirely from gas‐impermeable polycarbonate without tapes or gaskets. These chips replicate polarized villus‐like structures of the native tissue. Further, they enable co‐cultures of commensal anaerobic bacteria Blautia coccoides on the surface of gut epithelia for two days within a standard incubator. Another complication of commonly used materials in organ‐on‐chip devices is high ad‐/absorption, limiting applications in high‐resolution microscopy and biomolecule interaction studies. For future communication studies between gut microbiota and distal tumors, an additional polycarbonate chip design is developed to support hydrogel‐embedded tissue culture. These chips enable high‐resolution microscopy with all relevant processing done on‐chip. Designed for facile linking, this platform will make a variety of mechanistic studies possible.
Call to action for cross‐border conservation of the critically endangered Lake Chala tilapia (Oreochromis hunteri)
Authors: Mwangi E. M. 
Published: July 2024

AbstractLake Chala straddles the Kenya–Tanzania border, with a narrow strip of terrestrial habitat around it. The steep rocky shores are bedecked in a backdrop of Kilimanjaro at sunrise, giving the area the aesthetic beauty of an important tourist destination. The lake has important conservation implications ranging from endemic species including a critically endangered and rapidly declining fish to other unique biodiversity. This calls for urgent action to prevent extinction and promote sustainable management, building on previous work and action plans such as a proposed new conservancy, as the best safeguard against the threats.
A case of Williams syndrome with Wolff–Parkinson–White syndrome
Authors: Karadeniz Cem , Yıldız Kaan , Öksüz Sedef , Keçici Rüveyda Nur , Çoğulu Özgür 
Published: July 2024

AbstractIntroductionWilliams syndrome (WS) cases have been reported to have with 25–100 times greater increased risk of sudden cardiac death (SCD). SCD has been reported in cases without any evidence of structural cardiovascular anomalies. Wolff–Parkinson–White (WPW) syndrome is characterized by short PR interval and delta wave. Ventricular preexcitations can develop paroxysmal reentrant tachycardia through Kent bundle or less frequent atrial fibrillation and in some cases with accessory pathway effective refractory period (APERP) under 250 ms considered as risky and may lead to SCD. WS associated with WPW has not been reported before.Case ReportAn 11‐year‐old male who had been followed up with WS was referred to pediatric cardiology outpatient clinic with the complaint of palpitation. Electrocardiographic examination showed short PR interval and delta wave in the ECG consistent with WPW. He underwent electrophysiological study (EPS). Basic measurements were performed, and APERP was found at 280 ms cycle atrial pacing. RF energy was delivered using a 4 mm tip nonirrigated radiofrequency (RF) ablation catheter where the best ventriculoatrial (VA) signals were received and the AP was abolished within few seconds.Discussion and ConclusionsAlthough, WPW cases are usually asymptomatic or related to SVT, the risk of SCD should not be ignored. Thus, all patients with WPW deserve an EPS for assessing the AP conduction properties. Due to the increased risk of SCD in patients with WS compared to general population, in the presence of concomitant WPW, these patients should be evaluated with EPS even if they do not have symptoms.
Optical, vibrational, and photoluminescence properties of holmium‐doped boro‐bismuth‐germanate glasses
Authors: Rathaiah Mamilla , Ravanamma Rallapalli , Ravi Nirlakalla , Venkata Krishnaiah Kummara , Upendra Kumar Kagola , Nanda Kumar Reddy Nallabala , Naga Kiran Bangaram , Yuvaraj Chinnappa 
Published: July 2024

AbstractHolmium (Ho3+)‐doped boro‐bismuth‐germanate glasses having the chemical composition (30‐x)B2O3 + 20GeO2 + 20Bi2O3 + 20Na2O + 10Y2O3 + xHo2O3, where x = 0.1, 0.5, 1.0, and 2.0 mol% were prepared by melt‐quenching technique. The prepared glasses were examined for thermal, optical, vibrational, and photoluminescent properties. The prepared glasses were found to be thermally very stable. The optical bandgap and Urbach energies of 0.1 mol% Ho2O3‐doped boro‐bismuth‐germanate glass were calculated to be 3.3 eV and 377 MeV, respectively, using the absorption spectrum. The Judd–Ofelt analysis was performed on the 0.1 mol% Ho2O3‐doped glass and compared the obtained parameters with literature. The branching ratio (β) and emission cross‐section (σem) of the green band were determined to be 0.7 and 0.24 × 10−20 cm2, respectively. Under 450 nm excitation, a strong green emission around 550 nm was observed and assigned to the (5S2 + 5F4) → 5I8 (Ho3+) transition. Upon an increase of Ho2O3 content from 0.1 to 2.0 mol%, the intensities of all observed emission bands as well as decay time of the (5S2 + 5F4) → 5I8 transition have been decreased gradually. The reasons behind the decrease in emission intensity and decay time were discussed. The strong green emission suggests that these glasses may be a better option for display devices and green emission applications.
Biochemical and Structural Consequences of NEDD8 Acetylation
Authors: Kienle Simon Maria , Schneider Tobias , Bernecker Christine , Bracker Janina , Marx Andreas , Kovermann Michael , Scheffner Martin , Stuber Katrin 
Published: July 2024

AbstractSimilar to ubiquitin, the ubiquitin‐like protein NEDD8 is not only conjugated to other proteins but is itself subject to posttranslational modifications including lysine acetylation. Yet, compared to ubiquitin, only little is known about the biochemical and structural consequences of site‐specific NEDD8 acetylation. Here, we generated site‐specifically mono‐acetylated NEDD8 variants for each known acetylation site by genetic code expansion. We show that, in particular, acetylation of K11 has a negative impact on the usage of NEDD8 by the NEDD8‐conjugating enzymes UBE2M and UBE2F and that this is likely due to electrostatic and steric effects resulting in conformational changes of NEDD8. Finally, we provide evidence that p300 acts as a position‐specific NEDD8 acetyltransferase.