bluuebunny/crossref_metadata_2025_split huggingface dataset:
From individual to household decision‐making: A practical perspective on the base of the pyramid consumer
Authors: Lappeman James , Bundwini Nqobile , Chikweche Tendai 
Published: July 2024

AbstractThis paper proposes a new household decision‐making model for base of pyramid (BoP) consumers. Many decision‐making models focus on general consumer behaviour theory, with few focusing on the resource constraints experienced at the BoP. By focusing on the dynamics of household decisions, the data collected bring a unique perspective to BoP consumer behaviour and extend recent work in the BoP domain. The study comprised qualitative interviews with 61 household representatives (representing 233 household members) to explore decision‐making, loyalty, budgeting, shopping and category trade‐offs. The study proposes a household‐focused decision‐making framework, which is far more characteristic of BoP consumer behaviour (as opposed to isolated individual decisions). The proposed framework reveals the impact of situations and financial constraints on BoP household decision‐making and how most households operate in both the formal and informal economy. Family obligation was observed to be a key factor, as well as how functional illiteracy drives brand loyalty but also creates embarrassment. Word of mouth trumps all other sources of information and, due to household complexities, there is significant decision‐maker ambiguity, making it hard to define a target audience with a communication strategy. Brands are important, but fundamental value is still key and there is inexorable monthly variation in finances, making category trade‐offs commonplace.
Antidiabetic and Antioxidant Activities of Indian Bay Leaf (Cinnamomum tamala (Buch.‐Ham.) T. Nees & Eberm.) Essential Oils Collected from Meghalaya
Authors: Kumar Chaudhary Sushil , Kharlyngdoh Evanylla , Shukla Jitendra K. , Bhardwaj Pardeep K. , Thorat Sunil S. , Bhowmick Shovonlal , Sharma Nanaocha , Kumar Mukherjee Pulok 
Published: July 2024

AbstractThe current work investigates the chemodiversity, in vitro antioxidant, α‐amylase and α‐glucosidase inhibitory potential of Cinnamomum tamala (CT) leaf essential oil (EO) collected from different localities of East Khasi Hills District of Meghalaya, India. Gas chromatography‐mass spectrometry (GC‐MS) analysis of all the extracted leaf essential oils facilitated the identification of several compounds in a variable range along with eugenol as the major component (74.79–95.12 %). CT8 exhibited the highest antioxidant activity (IC50=11.23±0.27 μg/mL for 2,2‐diphenyl‐1‐picrylhydrazyl (DPPH) and IC50=21.54±0.37 μg/mL for 2,2’‐azino‐bis(3‐ethylbenzothiazoline‐6‐sulfonic acid (ABTS) among all EO evaluated. The results showed that the ferric reducing antioxidant power (FRAP) and oxygen radical absorbance capacity (ORAC) values for CT8 were 83.26±1.92 μM trolox/g oil and 70.29±1.90 ascorbic acid equivalents (AAE)/g of oil. α‐amylase and α‐glucosidase inhibition were highest in sample CT8 with IC50 values of 3.62±0.42 μg/mL and 16.29±0.32 μg/mL respectively. Caryophyllene, cyclohexene, 1, 5, 5‐trimethyl‐6‐(2‐propenylidene), germacrene D and eugenol showed strong binding potential toward α‐amylase and α‐glucosidase. It concluded that the chemodiversity and antidiabetic potential of C. tamla oil from Khasi Hills have never been studied. It can be taken as a dietary supplement as an antioxidant and antidiabetic to control blood glucose.
DNA‐Origami‐Armored DNA Condensates
Authors: Yamashita Nagi , Sato Yusuke , Suzuki Yuki , Ishikawa Daisuke , Takinoue Masahiro 
Published: July 2024

AbstractDNA condensates, formed by liquid–liquid phase separation (LLPS), emerge as promising soft matter assemblies for creating artificial cells. The advantages of DNA condensates are their molecular permeability through the surface due to their membrane‐less structure and their fluidic property. However, they face challenges in the design of their surface, e. g., unintended fusion and less regulation of permeable molecules. Addressing them, we report surface modification of DNA condensates with DNA origami nanoparticles, employing a Pickering‐emulsion strategy. We successfully constructed core‐shell structures with DNA origami coatings on DNA condensates and further enhanced the condensate stability toward fusion via connecting DNA origamis by responding to DNA input strands. The ‘armoring’ prevented the fusion of DNA condensates, enabling the formation of multicellular‐like structures of DNA condensates. Moreover, the permeability was altered through the state change from coating to armoring the DNA condensates. The armored DNA condensates have significant potential for constructing artificial cells, offering increased surface stability and selective permeability for small molecules while maintaining compartmentalized space and multicellular organization.
Multimodal Hard X‐Ray Nanotomography Probes Pore Accessibility of Technical Catalysts after Coking
Authors: Weber Sebastian , Karpov Dmitry , Kahnt Maik , Diaz Ana , Romanenko Yuliia , Kotrel Stefan , Haas Andreas , Hinrichsen Bernd , Bottke Nils , Grunwaldt Jan‐Dierk , Schunk Stephan , Sheppard Thomas L. 
Published: July 2024

AbstractCoking is a common catalyst deactivation route in industrial processes involving carbonaceous species. While coking is easy to diagnose, this is often performed by bulk analysis. Understanding specific symptoms such as pore blockage and obstruction of active sites is especially challenging for technical catalysts and requires a spatially‐resolved approach. Here a combination of ptychographic X‐ray computed tomography (PXCT) and X‐ray fluorescence nanotomography (XRF‐CT) could identify and allocate regions of coke deposition within a technical zeolite‐based propane dehydrogenation catalyst. PXCT is sensitive to the quantitative electron density of the sample, therefore indirectly visualising coke deposition in meso‐ and macropores with 56–61 nm 3D spatial resolution. For more direct visualisation the catalysts were treated with Cu solution as fluorescent marker, whereby complementary XRF‐CT analysis could distinguish accessible and blocked pores based on the presence or absence of adsorbed Cu. This strategy was used to assess coking as a function of time on stream, to evaluate coke removal by oxidative regeneration, and to distinguish the presence of coke deposits separately within the zeolite and binder components. This strategy is applicable to virtually any porous solid catalyst and can deliver previously unknown insights into the common phenomenon of coke deposition particularly in technical catalysts.
Recent Developments in Immobilized Photocatalyst for Hydrogen Production
Authors: Wang Kun , Luo Yixiang , Gu Chen , Zhi Ting , Wang Longlu , Yan Dafeng 
Published: July 2024

AbstractSolar‐driven water splitting for hydrogen production has emerged as one of the most promising methods for addressing environmental and energy crises. The utilization of immobilized photocatalyst for hydrogen production has attracted significant attention in recent years due to its excellent stability, high photocatalytic efficiency, and ease of recovery and reuse. Hence, a comprehensive review of the development of immobilized photocatalyst appears exceedingly significant. Herein, we initially analyze the advantages of the immobilized photocatalytic system in aspects such as light absorption, photon utilization, and charge separation. Subsequently, we introduce various assembly techniques for immobilized photocatalyst and elaborate on some representative characteristics of this immobilized system. Furthermore, we cite the examples of the application of immobilized photocatalyst in large‐scale hydrogen production to envision its future prospects. Finally, we discuss the remaining issues in this field and outline future directions of development and challenges therein. This review holds great promise for prompting the advancement of immobilized photocatalyst in the field of photocatalysis.
Evolutionary Abilities of Minimalistic Physicochemical Models of Life Processes
Authors: Pascal Robert 
Published: July 2024

AbstractThe ability of living organisms to persist, grow, evolve and invade environments seemingly challenges physical laws. Emerging Autonomous Systems representing autocatalytic cycles constituted of energized components in a state of Dynamic Kinetic Stability feature some of these properties. These simple theoretical models can grow, can be transferred but need an initiation to emerge and can collapse. Moreover, they can undergo kinetic selection in a way consistent with Darwinian behaviour, though they lack the ability to undergo change. The mere existence of these systems and their open‐ended growth potential are proposed to constitute a transmissible factor of a non‐coded kind. The onset and selection of epigenetic factors may therefore have preceded that of genetic polymers. Here is addressed the question of how these systems may arise from the diversity exhibited by abiotic organic matter, sometimes associated with intractable mixtures, which may actually be useful in providing initiators. The Darwinian description of evolution may therefore be merged without critical discontinuity within an origin scenario. Accordingly, such a theory would rests solely on physicochemical laws beginning with the potential of emerging autonomous systems to compete and invade the space dimension, and to further develop along other available dimensions including variability and, possibly, cognition.
Versatile Metal‐Free Arylation of BODIPY and Bis(BF2) Chromophores by Using Arylazosulfones in a Sunflow System
Authors: de Melo Shaiani Maria Gil , dos Santos Thiago , Silva Daniel Gedder , Martins Yugo Araújo , Eckhardt Paul , Lopez Renata Fonseca Vianna , Opatz Till , Protti Stefano , da Silva Emery Flavio 
Published: July 2024

AbstractBODIPYs have a well‐established role in biological sciences as chemosensors and versatile biological markers due to their chemical reactivity, which allows for fine‐tuning of their photophysical characteristics. In this work, we combined the unique reactivity of arylazo sulfones with the advantages of a “sunflow” reactor to develop a fast, efficient, and versatile method for the photochemical arylation of BODIPYs and other chromophores. This approach resulted in red‐shifted emitting fluorophores due to extended electronic delocalization at the 3‐ and 5‐positions of the BODIPY core. This method represents an advantageous approach for BODIPY functionalization compared to existing strategies.
Parameter sensitivity of a wood chips flow model
Authors: Evysdotter Sofia , Vikström Tomas , Rasmuson Anders 
Published: July 2024

AbstractA computational fluid dynamics (CFD) study of the parameter sensitivity of a wood chips model was performed on an industrial impregnation vessel, which is the first step in a continuous cooking system. The solid and liquid phases were both treated as continua and it was found that the continuum model for the solid wood chips phase could capture the previously observed oscillating formation of arches in the contracting part of the vessel, which will occur at different levels of volume fraction depending on the material constants. The parameters that were examined are the solid pressure, permeability, viscosity, and wall friction. It was found that all the parameters strongly affect the distribution of the wood chips in the vessel as well as the oscillation effects, hence also the flow field which is important to accurately predict in order to ensure optimal performance of the impregnation vessel. Thus, correct material data for these types of simulations are crucial to the outcome and should be chosen for the appropriate situation and bio‐material.
En Route to Diastereopure Polycyclic γ‐Lactones by Iridium‐Catalyzed Hydride Transfer†
Authors: Chen Yang , Zhang Jingyu , Wang Yecheng , Du Hongguang , Xu Jiaxi , Yang Zhanhui 
Published: July 2024

Comprehensive SummaryThe reductive lactonization strategy provides an efficient access to diastereoenriched polycyclic γ‐lactones. However, it is still a formidable challenge to develop an efficient and versatile protocol with excellent levels of diastereocontrol. Herein, we provide a highly diastereoselective and efficient route to diastereopure bi‐ and polycyclic γ‐lactones, by means of an iridium‐catalyzed hydride transfer strategy. This method features high levels of diastereocontrol, broad substrate scope, and high catalyst efficiency (S/C = up to 5000). Mechanistic studies suggest that the iridium hydride formation might be the rate‐determining step, and that the hydride transfer step be the diastereo‐determining step. The large steric hindrance of the iridium hydride species and intramolecular hydrogen bonding are critically key to the diastereocontrol of the hydride transfer process. From the perspectives of configurational analysis and Duniz angles of attack, the nature of diastereocontrol is well rationalized. A more general empirical rule based on facial selectivity analysis for explaining and predicting the stereochemistry is also proposed.
Purchase intention of brands with corporate social responsibility among generations Y and Z consumers in Chile
Authors: Bianchi Constanza , Hofer Katharina Maria , Saleh M Abu 
Published: July 2024

AbstractBrands around the world are recognizing the importance of committing to sustainable development through corporate social responsibility (CSR) initiatives. However, the literature shows scant empirical understanding of the purchase intention of younger consumers of Generations Y and Z regarding brands that engage in CSR initiatives. Drawing on the theory of planned behavior (TPB), the objective of this study is to develop and test an extended model of purchase intention for brands with CSR initiatives among the segment of Gen Y and Z consumers. The model is tested using an online survey applied to Chilean consumers and statistically analyzed using the structural equation modeling (SEM) technique. The findings show that attitude, subjective norms, and perceived behavioral control are significantly and directly related to the consumer's intention to purchase brands that demonstrate CSR initiatives. Further, consumer involvement and trust in brands' CSR initiatives have an indirect but significant effect on purchase intention through their impact on attitude. This research contributes to the literature on CSR and branding by addressing the role of consumers in supporting brands, which contribute to sustainable consumption. Findings can help brand managers and policymakers implement strategies to encourage consumer support for CSR initiatives.
Selective Multiphase‐Assisted Oxidation of Bio‐Sourced Primary Alcohols over Ru‐ and Mo‐ Carbon Supported Catalysts
Authors: Bersani Chiara , Rodríguez‐Padrón Daily , Ballesteros Daniel , Rodríguez‐Castellón Enrique , Perosa Alvise , Selva Maurizio 
Published: July 2024

AbstractThe oxidation of representative bio‐based benzyl‐type alcohols has been successfully carried out in a multiphase (MP) system comprised of three mutually immiscible liquid components as water, isooctane, and a hydrophobic ionic liquid as methyltrioctylammonium chloride ([CH3(CH2)6CH2]3N(Cl)CH3), a heterogeneous catalyst (either ad‐hoc synthesized carbon‐supported Mo or a commercial 5 % Ru/C), and air as an oxidant. The MP‐reaction proceeded as an interfacial process with Mo/C or Ru/C perfectly segregated in the ionic liquid phase and the reactant(s)/products(s) dissolved in the aqueous solution. This environment proved excellent to convert quantitatively benzyl alcohols into the corresponding aldehydes with a selectivity up to 99 %, without overoxidation to carboxylic acids. The nature of the catalyst, however, affected the operating conditions with Ru/C active at a lower T and t (130 °C, 4–6 h) compared to Mo/C (150 °C, 24 h). The phase confinement was advantageous also to facilitate the products isolation and the recycle of the catalyst. Notably, in the Mo/C‐catalyzed oxidation of benzyl alcohol, benzaldehyde was achieved with unaltered selectivity (>99 %) at complete conversion, for five subsequent reactions through a semicontinuous procedure in which the catalyst was reused in‐situ, without ever removing it from the reactor or treating it in any way.
Mass cytometric single cell immune profiles of peripheral blood from acute myeloid leukemia patients in complete remission with measurable residual disease
Authors: Sefland Øystein , Gullaksen Stein‐Erik , Omsland Maria , Reikvam Håkon , Galteland Eivind , Tran Hoa Thi Tuyet , Spetalen Signe , Singh Satwinder Kaur , Van Zeeburg Hester J. T. , Van De Loosdrecht Arjan A. , Gjertsen Bjørn Tore 
Published: July 2024

AbstractMeasurable residual disease (MRD) is detected in approximately a quarter of AML chemotherapy responders, serving as a predictor for relapse and shorter survival. Immunological control of residual disease is suggested to prevent relapse, but the mechanisms involved are not fully understood. We present a peripheral blood single cell immune profiling by mass cytometry using a 42‐antibody panel with particular emphasis on markers of cellular immune response. Six healthy donors were compared with four AML patients with MRD (MRD+) in first complete remission (CR1MRD+). Three of four patients demonstrated a favorable genetic risk profile, while the fourth patient had an unfavorable risk profile (complex karyotype, TP53‐mutation) and a high level of MRD. Unsupervised clustering using self‐organizing maps and dimensional reduction analysis was performed for visualization and analysis of immune cell subsets. CD57+ natural killer (NK)‐cell subsets were found to be less abundant in patients than in healthy donors. Both T and NK cells demonstrated elevated expression of activity and maturation markers (CD44, granzyme B, and phosho‐STAT5 Y694) in patients. Although mass cytometry remains an expensive method with limited scalability, our data suggest the utility for employing a 42‐plex profiling for cellular immune surveillance in whole blood, and possibly as a biomarker platform in future clinical trials. The findings encourage further investigations of single cell immune profiling in CR1MRD+ AML‐patients.
Exploring the Efficacy and Safety of Interleukin‐23 Inhibitors in Dissecting Cellulitis of the Scalp: A Comprehensive Review
Authors: Nagshabandi Khalid Nabil , Shadid Asem , Al‐Mashali Mohammed 
Published: July 2024

ABSTRACTBackgroundDissecting cellulitis of the scalp (DCS), also known as perifolliculitis capitis abscedens et suffodiens or Hoffmann disease, is a rare chronic inflammatory scalp condition with an unknown etiology. The US Food and Drug Administration (FDA) has recently approved multiple interleukin‐23 (IL‐23) inhibitors for chronic‐plaque psoriasis, and their off‐label use has shown promise in treating various dermatological conditions, including DCS. This review assesses the efficacy and safety of IL‐23 inhibitors for DCS, aiming to support potential FDA approval for severe refractory cases.MethodsA comprehensive literature search was conducted in February 2024 using MEDLINE, PUBMED, and Google Scholar with the keywords “Dissecting cellulitis,” “DCS,” “Interleukin‐23 inhibitors,” “IL‐23,” and “Biologics.” The search focused on identifying studies reporting the use of IL‐23 inhibitors in DCS treatment.ResultsThe search identified five cases where IL‐23 inhibitors were used to treat DCS. All patients were male, aged 17–65 years, with multiple comorbidities in four cases, primarily hidradenitis suppurativa and acne conglobata. The IL‐23 inhibitors Risankizumab, Guselkumab, and Tildrakizumab were used, resulting in significant clinical improvement, near‐complete remission, and hair regrowth. Additionally, psychosocial improvements were noted in two cases, with no reported adverse effects.ConclusionIL‐23 inhibitors have shown remarkable efficacy in treating severe DCS, with significant clinical and psychosocial improvements and a favorable safety profile. These findings support the consideration of FDA approval for IL‐23 inhibitors as a treatment option for refractory DCS cases, offering hope for patients with this challenging condition.
Applications of Plasma‐Rich Plasma, Exosomes, and Stem Cells in Aesthetics: A Narrative Review
Authors: Ablon Glynis , Smith Zoë Indigo , Munavalli Girish (Gilly) 
Published: July 2024

ABSTRACTIntroductionPlasma‐rich plasma (PRP), exosomes, and stem cells represent promising new treatments for facial rejuvenation and to enhance other cosmetic procedures. Although these treatments are rapidly advancing, there are no universally accepted treatment protocols for their use. The goal of the following review is to describe some of the possible benefits of PRP, exosomes, and stem cells in aesthetic medicine.ResultsA review of available studies showed that potential uses of PRP include wound healing after facial surgery, facial rejuvenation, androgenetic alopecia, acne scars, striae distensae, and vitiligo. Exosomes may provide beneficial treatment for skin rejuvenation, scar reduction, hyperpigmentation, and hair growth. Stem cells show promise for androgenetic alopecia, scar improvement, and treatment of photoaged skin. These new technologies may be used alone, but are often combined with existing aesthetic treatments.ConclusionPRP, exosomes, and stem cells may play an important role in restoring youthful tissue structure and function. Interpretation of some study results is sometimes challenged by the lack of standardized treatment protocols, including routes of application and dosing. When combined with other devices and techniques, results are sometime unclear as to which treatment plays the greater role.
Biometric variability of inflorescence and flower traits among ex situ accessions of the neotropical oilseed palm Acrocomia Mart.
Authors: Meyer Catherine , Hilger Thomas , Kuki Kalcida Naomi , Motoike Sérgio Yoshimitsu , Cadisch Georg 
Published: July 2024

AbstractThe oilseed palm genus Acrocomia is suitable for sustainable oil production in South America. The high phenotypic diversity of wild populations poses a challenge for the delimitation of the genus. Comparing the inflorescence architecture, a first‐order panicle, and staminate and pistillate flower traits could be a valuable tool in resolving the taxonomic disarray. Thus, this study aims to characterize the differences in the inflorescence architecture and floral structures of three common and economically significant Acrocomia species: A. aculeata, A. totai, and A. intumescens. Biometric traits of the inflorescence architecture and floral structures of various Acrocomia accessions in an ex situ germplasm collection in Brazil were assessed. The unweighted pair group method with arithmetic mean (UPGMA) cluster analysis based on the Gower distance was used to measure dissimilarities between the individual plants of the accessions. To our best knowledge, this study provides the first evidence of the presence of second‐order rachillae in the genus Acrocomia. Evaluated traits showed a high level of variation within and between accessions, emphasizing the phenotypic diversity of the genus. The accessions of A. totai were distinguishable from those of the other two species by their inflorescence architecture and flower traits. The dissimilarities between A. aculeata and A. intumescens were not sufficient to differentiate both. In conclusion, the quantitative assessment of inflorescence and floral traits is a valuable tool for taxonomic resolution of the genus.