bluuebunny/crossref_metadata_2025_split huggingface dataset:
Management of bid evaluation risks in procurement of construction projects of public tertiary institutions in Nigeria
Authors: Suleiman S. , Saidu I I. , Adamu A.D. , Tsado A.J. 
Published: June 2024

Bid evaluation stage in project procurement is considered to be one of the critical stages in the public procurement process in Nigeria. This stage determines the outcome of tendering process and can easily be manipulated by procurement officer that wants to favour a particular bidder to be awarded a contract. However, this stage is plagued with risks that impact on contract parties and project objectives. Thus, this article aimed to assess bid evaluation risks management startegies for construction procurement of tertiary institution in Nigeria with a view to ensuring effective delivery of construction projects. The study employed the survey design approach by administering 150 structured questionnaires to purposively selected construction professionals of procurement and physical planning units of tertiary institutions in three states and the Federal Capital Territory. The collected data were analysed using relative Importance Index (RII) to identify relatively the most important risks factors in the bid evaluation stage of procurement process . Regression analysis was employed to determine the impact of the identified bid evaluation risk factors on parties and the impact on project objectives. The study found that in -house information leakages to bidders (RII= 0.97), failure to declare a winner leading to subjective discussions or development of new criteria (RII= 0.87), unclear definition of technical specification (RII=0.85) and use of inappropriate evaluation criteria (RII= 0.80), are the important bid evaluation risks factors in construction procurement procurement. The study also found that the bid evaluation risks have statistically significant impact on project objective s in terms of time, cost, quality, safety and environment; as well as the parties to the contract all with p p-values less than 0.05 significance level level. It concluded that any change in the bid evaluation risk factors would lead to a corresponding change in the project objectives. It is recommended that procurement officer should use checklist guide and brainstorm on measure to beestablished to control bid evaluation risks for effective delivery of construc tion projects.
Assessment of Natural Radioactivity in Sediments and Groundwater from Selected Areas in Funtua Town, Katsina State, Nigeria
Authors: Tyongiga S. , Atsue T. , Joseph E. 
Published: June 2024

Natural radionuclides, particularly 238U, 232Th, and 40K are the main sources of radiation exposure. Therefore, their detection is key to radiation safety measurement, among others. Therefore, this study is aimed at assessing the natural radioactivity concentrations of 238U, 232Th, and 40K of 15 sediment and water samples from selected locations in Funtua town, Katsina state, Nigeria using gamma spectroscopy NaI (TI) and CR-39 Can detectors respectively. Data obtained show that, the activity concentrations in the sediment samples were found to range between 11.50 - 61.89, 7.15 – 69.46, and 646.01 – 1368.33 Bq/kg with average activity concentrations of 37.15, 35.66, and 914.73 Bq/kg for 238U,232Th, and 40K, respectively. These average values exceeded the worldwide values of 25, 25, and 370 Bq/kg respectively. In water samples, the values of 238U ranged from 0.20 to 36.78 Bq/L ( ); activity concentration values for 232Th radionuclide ranged from 2.75 Bq/L to 76.90 Bq/L ( ) and that of 40K radionuclide ranged from 42.28 Bq/L to 179.95 Bq/L ( ) respectively. These values are higher than the recommended value of 30000 g/L as reported by the EPA. The average activity concentrations of 238U,232Th, and 40K were found to be higher in the sediment samples than in the water samples. The estimated total annual effective dose AED in the water sample was found to be less than the worldwide values of 0.1mSv/y or 0.2 to 0.8. The excess life cancer risk ELCR of radon in the water ranged from 0.0983×10-4 to 1.8084×10-4 with a mean value of 0.7949×10-4. This value is less than the worldwide limit of 1.0×10-4. Therefore, the groundwater (wells) in Funtua town is said to be safe based on the effects of the activity concentrations of these natural primordial radionuclides and radon on the environment. However, the need for continuous monitoring should be a priority.
Challenges Confronting Cattle Farmers in Selected Farms in Ogun and Oyo States, Nigeria
Authors: Talabi Adewale O. , Sanni Fatimah Adenike , Adeleke Gabriel Adebayo , Awoyomi Olajoju J. , Adeleye Olushola E. 
Published: June 2024

Challenges confronting commercial cattle farms have caused the decrease in the productivity of cattle enterprises in Ogun and Oyo States, Nigeria. This study was carried out to investigate the challenges confronting cattle farmers in selected farms in Ogun and Oyo States. A semi-structured questionnaire was produced for 120 farmers which were equally distributed between the two states to gather relevant information that addressed the specific objectives of the study. The results showed that the farms in both States were characterized and grouped based on herd size, types of operation and years of operation. The herd size of 51-100 had the highest frequency (47; 39.2%) and 101-150 had the least frequency (12; 10%). Mixed farms had the highest frequency in types of operation (68, 56.7%) while dairy farms had the least (3, 2.5%). The years of operation greater than 10 years had the highest (53, 44%) while 1-5 years had the least. The farmers challenges include inadequate grazing area, disease, ectoparasitic infestation and non-availability of breeding stock among others. The levels of exposure to risk were based on the types of operation, years of operation, the state where the farm exist and herd size. The highest levels of frequency were used to determine the level of risk. In conclusion, commercial cattle farmers in Ogun and Oyo states are confronted with numerous challenges which range from inadequate grazing land, ectoparasites and diseases attack to lack of breeding stock. It is recommended that the Government of Nigeria should increase funding support to cattle farmers across the states for training on intensive management system, bio-security, water resources management, research and extension activities in the cattle production sector.
Growth Performance, Gut Histology and Anti-Coccidial Effect of Aqueous Blends of Scent Leaf, Ginger and Garlic in Broiler Chicken
Authors: Okusanya Phebe O. , Akinlad Olamilekan O. , Jarikre Theophilus A. , Ockiya Micheal A. 
Published: June 2024

This study was carried out to know the effects of scent leaf, ginger and garlic aqueous blend on the growth performance and intestinal coccidial oocysts in starter broiler chicken. One hundred and twenty (Cobb 500) broiler chicks were allotted to four treatments of thirty birds each and denoted as T1, T2, T3, and T4. The treatments were further subdivided into replicates of (10) birds each. Chicken on Treatment one (T1) received synthetic drugs, when necessary, in their drinking water while others were given aqueous blends of scent leaf (SLAE), garlic (GIAE), and ginger (GAAE) in their drinking water at 50ml/litre, respectively. Variations were observed among the treatments, in final body weight, feed conversion ratio, and coccidial oocysts count (FBW, FCR, and COC). Birds given GAAE in their drinking water had better FCR (2.31) than SLAE (2.48), GIAE (2.55) and control (3.02). The oocyst count observed from the treatments varied significantly. The initial oocyst count reveals the presence of coccidial oocyst in the feaces of the chicken across the treatments. A significant reduction was observed in the oocyst count weekly across the groups but remained higher in the control group until the anti- coccidial drug was administered. Treatment 4 (50 mL/Lit GAAE) shows no egg count (NEC) from the second week. This study concluded that 50 milliliters of; SLAE, GIAE, and GAAE added to one liter of drinking water can be employed as anti-coccidials and growth boosters in the production of broiler chickens.
Serological Investigation of Equine Influenza Virus in Polo Horses at the 2021 Jos Polo Tournament, Plateau State
Authors: Omoniwa David Oludare , Edeh Emmanuel Richard , Adola Jolly Amoche , Oyetunde Joshua , Alaba Bukola , Oyekan Oluwamuyiwa , Meseko Clement Adebajo 
Published: June 2024

Equine influenza (EI) is an important respiratory disease of equidae caused by the Equine influenza virus (EIV). The H3N8 and the H7N7 strains of the EIV have been reported in outbreaks of EI. Clinical signs exhibited by infected horses include but are not limited to pyrexia, dry, harsh cough, clear nasal discharge which may turn purulent a few days later, anorexia and lethargy. In this study, 115 polo horses from Kaduna, Nassarawa, Niger, Abuja FCT, Bauchi and Adamawa that participated in the 2021 Jos Polo Tournament were screened for EIV to ascertain the seroprevalence of EIV in these group of horses. Theses sera samples were tested using a specific commercially available indirect Influenza A Virus Antibody ELISA Test Kit (IDEXX Influenza A Test Kit). An overall prevalence of 51.3% was obtained. Subset of ELISA reactive sera were analysed by Haemagglutination Inhibition (HI) for subtype H3 and 6 out of 20 (30%) had up to 3log2 HI titre . In this study, the prevalence of influenza A was highest in female and Argentine horses. The effect of sex breed and location was statistically not significant. Additionally, this study showed that seropositive horses were present in each of the states represented, implying that EIV is still circulating in Nigeria. This study therefore highlights the need for regular monitoring and surveillance of equidae population in Nigeria for EIV to improve our understanding of EI and help in the formulation of national control strategies for EI.
Effect of anti-CD3-EGFR bispecific antibody-labeled DCCIK immune cells on proliferation of lung cancer cells
Authors: Li Minjie , Zhong Yuan 
Published: June 2024

Purpose: To investigate the effect of DC-CIK immune cells labeled with anti-CD3-EGFR bispecific antibody (BSAB) on the proliferation of lung cancer (LC) cells in order to generate data useful for enhancing the therapy of LC.
Methods: The anti-CD3 and anti-EGFR monoclonal antibodies were labeled on the surface of DC-CIK cells using chemical coupling method. Successful preparation of anti-CD3-EGFR BSAB was determined using SDS-PAGE. Two groups of cells were used: labeled group and a DC-CIK group. The cytotoxic effect on A549 LC cells was determined in vitro, and the tumor inhibition capacity was determined in 30 nude mice with LC.
Results: The killing rate of EGFR-positive A549 cells in labeled group was more severe than the killing rate in DC-CIK cells (p < 0.05). Cellular growth rate was significantly lesser in labelled A549 LC cells than in DC-CIK group. After 2 months of treatment, nude mouse tumor size in labeled group was smaller than the tumor volume in DC-CIK group. No obvious adverse reactions (ARs) were observed in both groups.
Conclusion: In vitro, CD3-EGFR BSAB-labeled DC-CIK immune cells produce cytotoxic effect and inhibit the proliferation of LC cells, while in vivo studies reveal that the cells produce good therapeutic effect on LC.
KARDIOVASKULÁRNÍ RIZIKO U PACIENTŮ HOSPITALIZOVANÝCH NA INTERNÍM ODDĚLENÍ: PRŮŘEZOVÁ STUDIE
Authors: Hujová Aneta , Zemanová Miroslava 
Published: June 2024

Úvod: Nomogram SCORE (Systematic Coronary Risk Evaluation system) je jedním z nejpoužívanějších skórovacích systémů pro českou populaci. Tento systém identifikuje možný vznik fatální kardiovaskulární příhody v následujících 10 letech či ve věku 60 let, tak je možné odhalit i asymptomatické mladé jedince v nízkém kardiovaskulárním riziku, ovšem s nezdravým životním stylem, který může v budoucnu zapříčinit vznik vysokého kardiovaskulárního rizika.
Cíl: Cílem studie bylo stanovit procentuální kardiovaskulární riziko u pacientů hospitalizovaných na interním oddělení (n = 64, 44 % žen; 56 % mužů), kteří byli hospitalizováni od 1. 4. – 1. 11. 2023.
Metodika: Vstupní kritéria pro zařazení do studie: hospitalizace od 1. 4. – 1. 11. 2023; podepsání písemného informovaného souhlasu; neprodělané kardiovaskulární onemocnění; nediagnostikovaný diabetes mellitus I. a II. typu či nediagnostikované renální selhání. Data byla získána osobním rozhovorem (věk, abúzus kouření), poté byl změřen systolický krevní tlak. Následně byla odebrána venózní krev, ze které se stanovila hladina celkového cholesterolu (mmol/l). Všechny tyto údaje byly následně porovnány s Nomogramem SCORE pro vysoce rizikové země.
Výsledky: Z výsledků vyplývá, že více jak 57 % respondentů bylo bez rizika vzniku fatální kardiovaskulární příhody, 18,8 % ve středním riziku a ve vysokém riziku 23,5 %.
Závěr: Průměrné riziko vzniku kardiovaskulární příhody v následujících 10 letech či ve věku 60 let se u většiny pacientů pohybovalo v nízkém intervalu (0-2 %), ovšem pro stanovení přesných rizikových faktorů je nutné pokračovat ve výzkumu a rozšířit vzorek pacientů.
EFEKT PSYCHOEDUKAČNÝCH INTERVENCIÍ POSKYTOVANÝCH SESTRAMI PACIENTOM SO SCHIZOFRÉNIOU: SCOPING REVIEW
Authors: Valachovičová Liliana , Tomagová Martina 
Published: June 2024

Východisko: Psychoedukácia má pre pacientov so schizofréniou mnohostranný význam. Je nevy-hnutnou súčasťou komplexnej starostlivosti o nich. Realizovaná je interdisciplinárnym tímom vrátene sestier.
Cieľ: Identifikovať efekt psychoedukácie realizovanej sestrami u pacientov so schizofréniou.
Metódy: Vyhľadávanie výskumných štúdií sa uskutočnilo v štyroch vedeckých multiodborových databázach, a to v PubMed, Web of Science, ScienceDirect a v Scopus. Z celkového počtu 398 štúdií bolo 11 štúdií zaradených do obsahovej analýzy. Proces triedenia štúdií bol realizovaný prostredníctvom PRISMA diagramu.
Výsledky: V analyzovaných štúdiách bol identifikovaný efekt psychoedukácie, na ktorej realizácii participovali sestry, v nasledovnách oblastiach: zmiernenie symptómov schizofrénie, podpora kompliancie a adherencie pacientov, redukcia dĺžky hospitalizácie a rehospita-lizácie pacientov, zvýšenie vedomostí a vhľadu pacientov na ochorenie, zlepšenie ich sociálneho fungovania a podpora zdravého životného štýlu.
Závery: Výsledky poskytujú dôkazy pre realizáciu opakovanej psychoedukácie pacientov so schizofréniou v rámci ošetrovateľskej starostlivosti poskytovanej v rôznych prostrediach klinickej praxe. Vzhľadom na limitácie metodiky štúdie i metodologické limitácie vyhľadaných štúdií tieto výsledky nie je možné zovšeobecňovať.
Bolalar viktimligining tasnifi va ularni kelib chiqishi sabablariga doir ilmiy yondashuvlar
Authors: Niyozova Salomat 
Published: June 2024

Mazkur maqolada bolalar viktimligining tasnifi va ularni kelib chiqishi sabablariga doir ilmiy yondashuvlar bayon etilgan. Shuningdek, maqolada “bola” tushunchasi bilan bogʻliq olimlarning fikrlari tahlil etilgan.
Shu bilan birga muallif maqolada bolalar maishiy zoʻravonlikka oʻsmirlarga qaraganda koʻproq duchor boʻlayotganliklari va bu ularning aqliy va hissiy rivojlanishiga salbiy taʼsir koʻrsatishi yuzasidan oʻz fikrlarini berib oʻtgan. Jumladan, bunday zoʻravonlikka uchragan bolalar katta boʻlgach, maktabda muammolarga duch kelishlari mumkin, tengdoshlari bilan muloqot qilishi qiyinlashib boraverishi, tushkunlikdan (depressiyadan), kuchli hayajon va boshqa ruhiy buzilishlardan aziyat chekishlari mumkinligi yuzasidan maqolada oʻz fikrlarini ilgari surgan.
Bundan tashqari, muallif maqolada oilaviy zoʻravonlik bilan yashaydigan bolalar koʻplab xavf-xatarlarga duch kelishi jumladan, travmatik hodisalarga duchor boʻlishi, qarovsiz qolishi, bevosita zoʻravonlik xavfi va ota-onasidan birini yoki ikkalasini yoʻqotish xavfi yuzaga kelishi haqida ham Bularning barchasi bolalar uchun salbiy oqibatlarga olib kelishi va ularga aniq taʼsir koʻrsatishi mumkinligi borasida ham taʼkidlab oʻtadi.
Mazkur maqolani yozish jarayonida muallif oiladagi zoʻravonlik bilan bogʻliq bolalar muammolarining uchta toifasi mavjudligini aniqlaydi.
Designing Authentic Assessment to Improve Academic Integrity
Authors: Lehane Sharon , Wright Angela 
Published: June 2024

The use of AI chatbots has sparked worldwide debate regarding assessment practices in higher education. Early indications on the use of AI chatbots, signal significant disruption to the higher education system in relation to academic misconduct concern. In terms of the research approach, initially, a systematic literature review was conducted to examine the association between academic integrity and authentic assessment with 32 focused publications from 2019 to 2023 analysed. This led to the development of a robust ‘Model for Practice’ to guide the implementation of authentic assessment in a way that simultaneously improved academic integrity. This paper presents the main findings of a case study approach with two final year student groups whose teaching and assessment schedule was based on this Model. Results show that the Model addresses the issue of assessing students in a manner that engages students, improves their employability skills, and ensures adherence to academic integrity guidelines.
Hipernatremia extrema asociado a choque indiferenciado
Authors: Masís-Mejía Rodrigo , García-Quirós Christian , Villegas Reyes José David 
Published: June 2024

El manejo y tratamiento de los trastornos hidroelectrolíticos constituyen aspectos fundamentales de la labor del internista, dado su impacto significativo en la mortalidad intrahospitalaria, especialmente en el caso de la hipernatremia. La hipernatremia extrema, se define como niveles de sodio superiores a 190 mmol/L, es una condición infrecuente pero crítica.Se presenta el caso de un paciente masculino de 44 años, sin antecedentes médicos onocidos, consumidor de sustancias derivadas de erythroxylum. Ingresó al servicio de emergencias con hipotensión marcada y una concentración sérica de sodio de 191 mmol/L. Tras su admisión a la unidad de medicina interna, se inició un enfoque integral de soporte y reposición hidroelectrolítica.Durante su hospitalización, se observaron signos compatibles con crisis adrenal y poliuria. Estudios del eje endocrino revelaron panhipopituitarismo y datos compatibles con diabetes insípida central. El paciente recibió tratamiento con desmopresina e hidrocortisona, resultando en la estabilización de la presión arterial y la corrección gradual de la hipernatremia. La tomografía cerebral reveló lesiones consistentes con un evento cerebrovascular, postulado como la causa subyacente del panhipopituitarismo.
La evaluación exhaustiva del eje endocrino se completó, permitiendo la implementación de reposición hormonal. El paciente fue dado de alta para seguimiento ambulatorio tras la estabilización clínica. Este reporte de caso detalla el abordaje médico inicial de la hipernatremia extrema, destacando la importancia de una evaluación diagnóstica integral en situaciones clínicas complejas.
Separación por exclusión salina de compuestos bioactivos de epicarpio de frutos aguacate (Persea americana Mill.) ‘Hass’ durante la maduración
Authors: Jiménez-Velázquez Perla , Valle-Guadarrama Salvador , Alia-Tejacal Iran , Salinas-Moreno Yolanda , García-Cruz Leticia 
Published: June 2024

La industrialización del fruto de aguacate (Persea americana Mill.) ‘Hass’ genera residuos, como la cáscara o epicarpio, que contiene compuestos que pueden aprovecharse. El objetivo del trabajo fue separar compuestos bioactivos de epicarpio de frutos de aguacate ‘Hass’ a lo largo de la maduración mediante procedimientos de exclusión salina o extracción acuosa en dos fases (ATPE). Se utilizó un sistema ATPE con una mezcla de citrato trisódico (Na3C3H5O(COO)3) y polietilenglicol 4000 (Peg4000) en concentración de 24.94 y 14.53 %, respectivamente, con la cual se demostró que es factible recuperar el 85.3 % de fenoles solubles presentes en el epicarpio del fruto. La separación de compuestos bioactivos aumentó conforme avanzó la maduración y las mayores cantidades de fenoles solubles totales, flavonoides, antocianinas y taninos condensables coincidieron con la madurez de consumo, con valores de 1866.5, 717.6, 64.0 y 1635.1 μg mL‑1, respectivamente, en la fase extractora. El método de ATPE puede ser una estrategia para aprovechar el epicarpio del aguacate ‘Hass’.
Cannabidiol (Epidiolex)
Authors: CADTH  
Published: June 2024

CADTH reimbursement reviews are comprehensive assessments of the clinical effectiveness and cost-effectiveness, as well as patient and clinician perspectives, of a drug or drug class.
The assessments inform non-binding recommendations that help guide the reimbursement decisions of Canada's federal, provincial, and territorial governments, with the exception of Quebec.
This review assesses cannabidiol (Epidiolex), 100 mg/mL, oral solution
Indication : Use as adjunctive therapy for the treatment of seizures associated with Lennox-Gastaut syndrome, Dravet syndrome, or tuberous sclerosis complex in patients 2 years of age and older.
INFORMATION-MODELING SYSTEM FOR THE HEAT LOSSES CONTROL IN THE BLAST FURNACE LOWER PART
Authors: Спирин Н.А. , Гурин И.А. , Лавров В.В. , Истомин А.С. , Зайнуллин Л.А. 
Published: June 2024

В статье представлена общая характеристика алгоритма определения тепловых потерь в горне доменной печи, основанного на использовании теплового баланса нижней зоны. Тепловые потери в процессе плавки в окружающую среду происходят через фурменный пояс, распар и заплечики и определяются по разности приходной и расходной частей зонального теплового баланса для нижней ступени теплообмена. Определение потерь тепла по балансу тепла в нижней ступени теплообмена позволяет оценивать их величину по текущей информации о работе печи в конкретных сырьевых и режимных параметрах работы. Представлено информационное обеспечение системы, описана архитектура программного обеспечения, дана характеристика программных модулей и проиллюстрированы фрагменты его работы. Информационно-моделирующая система отличается учетом основных физико-химических закономерностей процессов управления, принципов системного анализа, использованием современных принципов разработки и построения математических моделей, алгоритмического и программного обеспечения. Контроль тепловых потерь необходим для оценки состояния огнеупорной кладки доменной печи, рационального газораспределения, а также для корректировки расхода кокса.
The article presents a description of the structure of the algorithm, mathematical and software systems. The general characteristics of the algorithm for determining heat losses in the hearth of a blast furnace based on the use of the heat balance of the lower zone are presented. Heat losses in the process of melting into the environment occur through the tuyere belt, steam and shoulders, determined by the difference between the incoming and outgoing parts of the zonal heat balance for the lower stage of heat exchange. Determination of heat losses by the heat balance in the lower stage of heat exchange makes it possible to estimate their value according to the current information about the operation of the furnace in specific raw material and operating parameters. The information support of the system is presented, the software architecture is described, the characteristics of the software modules are given, and fragments of its work are illustrated. The information modeling system is distinguished by taking into account the basic physical and chemical laws of the processes of the control object, the principles of system analysis, the use of modern principles for the development and construction of mathematical models, algorithmic and software. Heat loss control is necessary to assess the condition of the blast furnace refractory lining, rational gas distribution, and also to adjust the coke consumption.