bluuebunny/crossref_metadata_2025_split huggingface dataset:
Social science Eurocentrism in the land of universalism: An introduction to French blindness
Authors: Dufoix Stéphane 
Published: July 2024

AbstractFrom the late 18th century onwards, France has delivered a universalistic discourse about politics, society, rights and also science. The emergence of social science largely confirmed this trend. Nowadays the growing challenging of Eurocentrism that has become more and more visible since the early 1990s remains most often untranslated, untaught, uninvestigated and undebated. The disciplinary structure of the university as well as the lingering isolationism of French social science accounts for part of this situation, the latter requires some further explanations. If some opening has recently been visible in the field of gender, race and discriminations, it has usually meant a greater influence of some—White or Black—American anthropologists, sociologist or philosophers, but hardly ever of non‐Western thinkers. The very issue of a social science canon is not even raised. The main reason for this is the weight of French neo‐republicanism as it was born in the early 1990s at the very same time when anti‐Eurocentric alternatives discourses became more widely heard. It results in a persistent denial of these discourses as being scientific and a widespread ignorance of them in the academic field.
Parents’ differential trait, mental state, and coping talk about White and Black child storybook characters
Authors: Fraser Ashley M. , Reschke Peter J. , Busby Andrea K. , Takamasa Emily J. , Jasperson Jennie , Sycamore Bethany 
Published: July 2024

AbstractLimited literature has examined parents’ unsolicited trait, mental state, and coping talk about media characters by race as they co‐view with their children. We observed 195 US parents describing an illustrated depiction of racialized social exclusion for their child (53% male; Mage = 5.46 years; 60% White) in their home setting. Families discussed a Black child being excluded by White children or a White child being excluded by Black children. Parents’ victim, emotion, personality, and coping talk about the excluded child were coded. Parents were more likely to use victim talk (e.g., “she's being excluded”) and emotion talk (e.g., “she's sad”) when the excluded child was Black and were more likely to use personality talk (e.g., “she's shy”) when the excluded child was White. We further explored parents’ demographic, personal, and neighborhood correlates with their trait, mental state, and coping talk. White parents with greater levels of egalitarian attitudes used more victim talk and coping talk (e.g., “she should go play with them”) about the White excluded child. Being more politically conservative was associated with White parents using more coping talk about the Black excluded child. White parents living in predominantly Black neighborhoods were less likely to use victim talk toward the Black child. BIPOC parents showed more nuanced patterns. These findings suggest that parents’ unsolicited racial messaging varies by racial identification, sociodemographic characteristics, and neighborhood context.
Evaluation test and analysis of a microneedle and iontophoresis based medical device “CELLADEEP Patch” in skin improvement on ex vivo human‐derived skin tissue models
Authors: Zhang Xin Rui , Jin Yong Xun , Chien Pham Ngoc , Tien Trinh Thi Thuy , Zhou Shu Yi , Giang Nguyen Ngan , Le Linh Thi Thuy , Nam Sun Young , Heo Chan Yeong 
Published: July 2024

AbstractBackgroundMicroneedles are tiny needles, typically ranging from tens to hundreds of micrometers in length, used in various medical procedures and treatments. The tested medical device named “CELLADEEP Patch” a dissolvable microneedle therapy system (MTS), made of hyaluronic acid and collagen. And the iontophoresis technique is also applied in the system. The study aimed to evaluate the effectiveness of the “CELLADEEP Patch” in skin improvement.MethodsEx vivo human‐derived skin tissue models were used in this study and they were divided into three different groups, namely, the Untreated Group, the Negative Control Group, and the Test Group respectively. The Untreated Group received no treatment measures, the Negative Control Group was exposed to ultraviolet B radiation (UVB) irradiation, and the Test Group was exposed to UVB irradiation and treated with “CELLADEEP Patch”. Skin moisture content, transdermal water loss, and skin elasticity were evaluated by three clinical devices. Additionally, histological staining and related mRNA expression levels were also analyzed.ResultsThe results of skin moisture content, transdermal water loss, and skin elasticity evaluation consistently illustrated that the application of “CELLADEEP Patch” led to remarkable skin improvement. And the analysis of histological staining images also confirmed the effectiveness of the “CELLADEEP Patch”, especially for increasing collagen density. Moreover, the upregulation of Collagen type 1 a (COL1A1) and hyaluronan synthase 3 mRNA expression and the decrease of Matrix metalloproteinase 1 (MMP‐1) and Interleukin‐1 beta (IL‐1β) mRNA expression reflected its wrinkle improvement, moisturizing and anti‐inflammation function.Conclusion“CELLADEPP Patch”, the MTS combined with the iontophoresis technique, exhibits its effectiveness in moisturizing, skin elasticity improvement, and anti‐inflammatory function when applied to ex vivo human‐derived skin tissue models in experiments. The study has contributed to the understanding of the “CELLADEPP Patch” and laid the foundation for subsequent animal experiments and clinical trials.
Gut microbiota, skin microbiota, and alopecia areata: A Mendelian randomization study
Authors: Li Zishun , Zhao Changpu , Chen Renwu , Li Meiling , Wang Fei , Hao Chenyuan , Li Rongzhi , Zhang Yu , Xu Yuying 
Published: July 2024

AbstractBackgroundObservational studies have shown an association between skin microbiota and alopecia areata (AA), but the causal connection remains ambiguous.MethodsWe obtained data on skin microbiota and AA from summary statistics of Genome‐Wide Association Studies and applied statistical methods from Mendelian randomization (MR) to assess causal relationships. Additionally, we investigated whether the skin microbiota acts as a mediator in the pathway from gut microbiota to AA.ResultsIn the MR analysis of KORA FF4 and AA, the inverse‐variance weighting method indicated that Corynebacterium (odds ratio [OR] = 0.82, 95% confidence interval [CI]: 0.70–0.96, p = 0.02) and asv037 (OR = 0.87, 95% CI: 0.76–0.99, p = 0.05) exerted protective effects, while Betaproteobacteria (OR = 1.21, 95% CI: 1.01–1.44, p = 0.03), asv015 (OR = 1.27, 95% CI: 1.05–1.54, p = 0.02), and Burkholderiales (OR = 1.20, 95% CI: 1.04–1.38, p = 0.01) were identified as risk factors in AA. In the MR analysis of PopGen and AA, asv001 (OR = 1.12, 95% CI: 1.01–1.24, p = 0.04), asv054 (OR = 1.13, 95% CI: 1.01–1.25, p = 0.03), and asv059 (OR = 1.14, 95% CI: 1.02–1.27, p = 0.02) were found to potentially increase the risk in AA. Furthermore, in the influence of gut microbiota on AA, the skin microbiota did not act as a mediator.ConclusionOur analysis suggests potential causal relationships between certain skin microbiota and AA, revealing insights into its pathogenesis and potential intervention strategies.
The relationship between psoriasis and vitiligo: From a comprehensive study
Authors: Li Junchen , Shen Qian , Wang Yingdong , Guo Chenqi , Ma Yuxiao , Zhang Yu 
Published: July 2024

AbstractBackgroundBoth psoriasis and vitiligo are autoimmune skin diseases. Previous observational studies have indicated a relationship between the two conditions, and simultaneous onset of both diseases poses increased health risks to patients. However, limited research has explored the causal relationship between psoriasis and vitiligo.ObjectivesTo investigate whether a causal association exists between psoriasis and vitiligo.MethodsA case of Chinese patients diagnosed with psoriasis and vitiligo has been reported. Transcriptome sequencing was performed on normal, psoriasis, vitiligo, and co‐morbid skin tissues of the patients, and single‐cell transcriptome sequencing was conducted on the co‐morbid skin tissues. A comprehensive Mendelian randomization analysis of Genome‐wide association studies (GWAS) was performed on a cohort of 261 018 European individuals with psoriasis from the IEU Open GWAS Project and vitiligo from the National Institutes of Health (NIH) Database of Genotypes and Phenotypes.ResultsCase report and transcriptome results showed that skin tissue with vitiligo combined with psoriasis exhibited both vitiligo and psoriasis. Single‐cell transcriptome sequencing results showed that in comparison to normal skin and psoriatic skin, the proportions of CD8+ T cells, natural killer cells, naive T cells, T helper cells 17, regulatory T cells, conventional type 1 dendritic cells, Conventional type 2 dendritic cells, and plasmacytoid dendritic cells were all increased in skin tissue with vitiligo combined with psoriasis. Mendelian randomization analysis included 4510 patients with psoriasis and 4680 patients with vitiligo. The results showed no causal relationship between vitiligo and psoriasis in the forward direction (p = 0.192; odds ratio [OR], 1.059; 95% confidence interval [CI], 0.971–1.155) or in the reverse direction (p = 0.459; OR, 0.927; 95% CI, 0.757–1.134).ConclusionsThis study suggests that the association between psoriasis and vitiligo may be closely related to immunity, however, Mendelian randomization studies do not support a causal relationship. These findings hold significant implications for clinicians aiming to enhance their understanding and treatment approaches for psoriasis and vitiligo.
The problem of the variable in Quine's perspicuous lingua franca of the sciences
Authors: Day Ivory 
Published: July 2024

AbstractSome 55 years after the publication of Russell's seminal ‘On Denoting’, Quine adopted the theory of definite descriptions presented therein to formulate his perspicuous lingua franca for the sciences. This paper illustrates how, in so doing, Quine's lingua franca inherited an old antinomy at the core of Russell's theory of definite descriptions, specifically, the lack of congruency between notation and metaphysical commitments when the variable assumes the role of fundamental singular reference. In this context, the paper contends that the phrase ‘to be is purely and simply to be the value of the variable’ is far from the straightforward solution Quine initially envisioned for his lingua franca. Additionally, it argues that it is unlikely that an attempt to account for a determinate object theory, such as those propounded by Russell and Quine, can prove successful when grounded in a referential theory of quantificational logic where the variable, seen as a simple range of values, holds fundamental singular referent‐position. The paper concludes by suggesting that Meinong's object theory could resolve the problem of the variable, albeit at the cost of potentially undesirable ontological and logical commitments. Alternatively, Kit Fine's recent work on other antinomies in the variable may provide a promising approach to exploring how to salvage the variable as a formal foundation for ontology.
PP2C phosphatase Pic14 negatively regulates tomato Pto/Prf‐triggered immunity by inhibiting MAPK activation
Authors: Chakraborty Joydeep , Sobol Guy , Xia Fan , Zhang Ning , Martin Gregory B. , Sessa Guido 
Published: July 2024

SUMMARYType 2C protein phosphatases (PP2Cs) are emerging as important regulators of plant immune responses, although little is known about how they might impact nucleotide‐binding, leucine‐rich repeat (NLR)‐triggered immunity (NTI). We discovered that expression of the PP2C immunity‐associated candidate 14 gene (Pic14) is induced upon activation of the Pto/Prf‐mediated NTI response in tomato. Pto/Prf recognizes the effector AvrPto translocated into plant cells by the pathogen Pseudomonas syringae pv. tomato (Pst) and activate a MAPK cascade and other responses which together confer resistance to bacterial speck disease. Pic14 encodes a PP2C with an N‐terminal kinase‐interacting motif (KIM) and a C‐terminal phosphatase domain. Upon inoculation with Pst‐AvrPto, Pto/Prf‐expressing tomato plants with loss‐of‐function mutations in Pic14 developed less speck disease, specifically in older leaves, compared to wild‐type plants. Transient expression of Pic14 in leaves of Nicotiana benthamiana and tomato inhibited cell death typically induced by Pto/Prf and the MAPK cascade members M3Kα and Mkk2. The cell death‐suppressing activity of Pic14 was dependent on the KIM and the catalytic phosphatase domain. Pic14 inhibited M3Kα‐ and Mkk2‐mediated activation of immunity‐associated MAPKs and Pic14 was shown to be an active phosphatase that physically interacts with and dephosphorylates Mkk2 in a KIM‐dependent manner. Together, our results reveal Pic14 as an important negative regulator of Pto/Prf‐triggered immunity by interacting with and dephosphorylating Mkk2.
Reviewer Acknowledgements for International Journal of English and Cultural Studies, Vol. 7, No. 1
Authors: Howard Nina 
Published: July 2024

International Journal of English and Cultural Studies (IJECS) would like to acknowledge the following reviewers for their assistance with peer review of manuscripts for this issue. Many authors, regardless of whether IJECS publishes their work, appreciate the helpful feedback provided by the reviewers. Their comments and suggestions were of great help to the authors in improving the quality of their papers. Each of the reviewers listed below returned at least one review for this issue. Reviewers for Volume 7, Number 1Abdelhamid M. Ahmed, Helwan University, EgyptAli Dabbagh, Gonbad Kavous University, IranAli Hashemi, Yazd University, IranEmmanuel Chibuzor Okereke, National Examinations Council, Enugu State Office, Enugu, NigeriaGillian Steinberg, SAR High School, USAHerman, University of HKBP Nommensen, IndonesiaNicolau Nkiawete Manuel, Agostinho Neto University, AngolaRoberto Gigliucci, Sapienza University of Rome, ItalyShashi Naidu, Ball State University, United StatesVesselina Anastasova Laskova, University of Udine, ItalyZhongfeng Huang, Beihang University, China
Advances in induced pluripotent stem cell‐derived cardiac myocytes: technological breakthroughs, key discoveries and new applications
Authors: Clancy Colleen E. , Santana L. Fernando 
Published: July 2024

AbstractA transformation is underway in precision and patient‐specific medicine. Rapid progress has been enabled by multiple new technologies including induced pluripotent stem cell‐derived cardiac myocytes (iPSC‐CMs). Here, we delve into these advancements and their future promise, focusing on the efficiency of reprogramming techniques, the fidelity of differentiation into the cardiac lineage, the functional characterization of the resulting cardiac myocytes, and the many applications of in silico models to understand general and patient‐specific mechanisms controlling excitation–contraction coupling in health and disease. Furthermore, we explore the current and potential applications of iPSC‐CMs in both research and clinical settings, underscoring the far‐reaching implications of this rapidly evolving field.
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Melting Behavior Effect of MXene Nanoenhanced Phase Change Material on Energy and Exergy Analysis of Double and Triplex Tube Latent Heat Thermal Energy Storage
Authors: Srivastava Utkarsh , Sahoo Rashmi Rekha 
Published: July 2024

Abstract
The impacts of melting behavior on the thermal performance of triple tube thermal energy storage (TT-TES) and double tube thermal energy storage (DT-TES) systems employing cetyl alcohol and 3% v/v. MXene nano-enhanced PCM (NEPCM) are compared and numerically evaluated in this work. For both the DT-TES and TT-TES systems, the following were investigated in connection to melting time: system efficiency, discharged energy, heat transfer rate, exergy destruction, entropy generation number, exergetic efficiency, melting fraction, and melting temperature contours. In addition, the effect of Stefan, Rayleigh, and Nusselt numbers on Fourier numbers are compared for the DT-TES and TT-TES systems with MXene NEPCM. MXene-based nano-enhanced PCM melting in TT-TES displayed 6.53% more Stefan number than cetyl alcohol. DT-TES with pure cetyl alcohol phase change material (PCM) consumes 0.4% more energy at 7800 s than MXene NEPCM. Pure melting of MXene-based nano-enhanced PCM in a TT-TES had 4.16% higher storage exergy than cetyl alcohol. The entropy generation number of pure melting of MXene-based nano-enhanced PCM in TT-TES is 7.93% lower than that of cetyl alcohol. Pure melting of MXene-based nano-enhanced PCM in TT-TES reduces storage energy by 1.95% over cetyl alcohol. Pure cetyl alcohol has 76.99% optimal system efficiency at 5400 s melting time and MXene NEPCM 77.04% at 4800 s in DT-TES. The charging temperature for pure cetyl alcohol PCM in TT-TES is 0.7% lower than in DT-TES. Furthermore, pure melting of MXene-based nano-enhanced PCM in a TT-TES has 1.95% lower storage energy than cetyl alcohol. For a given volume of MXene-based nano-enhanced cetyl alcohol PCM, melting occurs more rapidly in a TT-TES system.
Prestressing Estimation for Multilayer Clamping High Pressure Vessel Laminates
Authors: Xiao Zhengyan , Wang Xuesheng , Wang Hao , Cao Jiaming , Yuan Yuyang 
Published: July 2024

Abstract
The stresses on multilayer high pressure vessels during service have been extensively studied. However, there is still a lack of detailed and reliable theoretical analyses of a series of hidden problems in manufacturing, such as the prestressing of laminates during the manufacturing process and, where relevant, the initial inner cylinder thickness. In order to solve the problem of prestressing estimation for laminates, in this study, based on the assumption of uniform contact pressure, the equations for the interlaminar contact pressure as well as the residual circumferential stress expressed in terms of the initial circumferential stress of the laminate are derived and verified by finite element analysis (FEA). In the 16-layer model, the maximum positive deviation was +1.47%, and the maximum negative deviation was −0.08%. Theoretical equations show that each laminate layer can produce a larger residual compressive stress on the inner cylinder at a smaller circumferential stress, thus improving the fatigue performance of the multilayer vessels. As the number of layers increases, the inner cylinder may first experience external pressure destabilization, and thus the contact pressure P1 at the outer wall surface of the inner cylinder needs to be controlled to remain below the critical pressure Pcr of the inner cylinder.
Auxetic Structure Inspired Microneedle Arrays for Minimally Invasive Drug Delivery
Authors: Amer Maher , Fisher Christina , Small Georgia , Bullock Blake , Salinas Vero Vargas , Langford Jaden 
Published: July 2024

Abstract
Microneedle arrays (MNAs) are promising drug delivery tools aimed at lowering invasiveness and pain. Many design parameters are optimized to lower penetration force in MNAs. An important parameter is the microneedle width as that relates directly to the force required to penetrate the skin, the lower the width, the lower the penetration force needed. This research explored the use of auxetic structures known for having negative Poisson's ratio in the design of MNAs. As the needles are inserted, the compression on the needles causes their radial dimension to shrink instead of increasing as in positive Poisson's ratio structures. This study has shown a 25% reduction in penetration force due to using an auxetic structure instead of a conventional nonauxetic structure. The research employs additive manufacturing and soft molding to fabricate the MNAs. This study emphasizes the viability of using auxetic structures in MNA design.
Localization of Upstream Obstacles by Learning From Spectra of the Koopman Operator
Authors: Rodwell Colin , Tallapragada Phanindra 
Published: July 2024

Abstract
Objects moving in water or stationary objects in streams create a vortex wake. An underwater robot encountering the wake created by another body experiences disturbance forces and moments. These disturbances can be associated with the disturbance velocity field and the bodies creating them. Essentially, the vortex wakes encode information about the objects and the flow conditions. Underwater robots that often function with constrained sensing capabilities can benefit from extracting this information from vortex wakes. Many species of fish do exactly this, by sensing flow features using their lateral lines as part of their multimodal sensing capabilities. Besides the necessary sensing hardware, a more important aspect of sensing is related to the algorithms needed to extract the relevant information about the flow. This paper advances a framework for such an algorithm using the setting of a pitching hydrofoil in the wake of a thin plate (obstacle). Using time series pressure measurements on the surface of the hydrofoil and the angular velocity of the hydrofoil, a Koopman operator is constructed that propagates the time series forward in time. Multiple approaches are used to extract dynamic information from the Koopman operator to estimate the plate position and are bench marked against a state-of-the-art convolutional neural network (CNN) applied directly to the time series. We find that using the Koopman operator for feature extraction improves the estimation accuracy compared to the CNN for the same purpose, enabling “blind” sensing using the lateral line.
Optimal Control for Thermal Management of a Proton Exchange Membrane Fuel Cell Stack With Koopman-Based Modeling
Authors: Huo Da , Hall Carrie M. 
Published: July 2024

Abstract
This study presents a novel approach to optimal control utilizing a Koopman operator integrated with a linear quadratic regulator (LQR) to enhance the thermal management and power output efficiency of an open-cathode proton exchange membrane fuel cell (PEMFC) stack. First, a linear time-invariant dynamic model was derived through Koopman operator to forecast the behavior of the PEMFC stack. Second, this Koopman-based model was directly integrated with LQR for optimizing temperature, temperature variations, and output power efficiency of the PEMFC stack by regulating fan speed, with a physics-based model serving as the plant model. Finally, the performance of the Koopman-based LQRs (KLQR) was compared to a baseline proportional-integral (PI) controller across various ambient temperatures and operating conditions, focusing on temperature, temperature variations, and net power output. The results demonstrate the proposed Koopman-based approach can be seamless integration with linear optimal control algorithms, effectively minimizing temperature, temperature variations across the PEMFC stack, and the net power outputs under different ambient temperature and operating conditions.