bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Comprehensive Kinetic Model of Free‐Radical‐Mediated Interfacial Polymerization
Authors: Shenoy Raveesh , Bowman Christopher N. 
Published: January 2013

AbstractA mathematical model describing interfacial radical polymerization‐based film formation on hydrogels is elucidated. A glucose oxidase‐mediated multistage initiation reaction is used to accomplish interfacial film formation. A polymer concentration‐dependent diffusion coefficient is used to reflect the changing mass transport conditions as the film develops. Model predictions of the film thickness as a function of the species concentrations agree well with experiments. The model predicts that the degree of initiation reaction delocalization with the enzyme‐mediated initiation system is significantly higher than an enzyme‐independent system, thus affecting the film growth rate and structure. The mass transport properties of the film and its adhesion to the underlying substrate are also investigated. magnified image
iSchools and l‐schools: Converging or diverging communities?
Authors: Lopatovska Irene , Pattuelli M. Cristina , Bates Marcia J. , Buckland Michael , Dalbello Marija , Hastings Samantha , Giannini Tula 
Published: January 2013

AbstractThe panel will discuss the intellectual differences between iSchool and Information Science programs that are not part of the iSchool Caucus, referred here as L‐Schools. The panelists, who represent both communities, will discuss the foundational, philosophical, and formal differences between the two types of programs, and focus on the intellectual diversity of the two academic communities.
Arabic web interface design through the eyes of Hofstede
Authors: Khashman Nouf , Large Andrew 
Published: January 2013

AbstractThis study examines selected design characteristics of government Web interfaces from ten Arab countries using Hofstede's cultural dimensions. Organizational and graphical elements from 100 ministry Web interfaces from Jordan, Syria, Yemen, Sudan, Morocco, Tunisia, Algeria, Bahrain, Qatar, and Oman were examined using content analysis method. The results suggest that Hofstede's model of culture does not fully reflect the design characteristics of these interfaces.
Analytical and computational procedure for solving the consolidation problem of layered soils
Authors: Sadiku S. 
Published: January 2013

SUMMARYOne‐dimensional consolidation analysis of layered soils conventionally entails solving a system of differential equations subject to the flow conditions at the bounding upper and lower surfaces, as well as the continuity conditions at the interface of every pair of contiguous layers. Formidable computational efforts are required to solve the ensuing transcendental equations expressing the matching conditions at the interfaces, using this method. In this paper, the jump discontinuities in the flow parameters upon crossing from one layer to the other have been systematically built into a single partial differential equation governing the space–time variation of the excess pore pressure in the entire composite medium, by the use of the Heaviside distribution. Despite the presence of the discontinuities in the coefficients of the differential equation, a closed‐form solution in the sense of an infinite generalized Fourier series is obtained, in addition to which is the development of a Green's function for the differential problem. The eigenfunctions of the composite medium are the coordinate functions of the series, obtained computationally through the application of the extended equations of Galerkin. The analysis has been illustrated by solving the consolidation problem of a four‐layer composite, and the results obtained agree very well with the results obtained by previous researchers. Copyright © 2013 John Wiley & Sons, Ltd.
Manual for the Preparation and Staining of Embedded Natural Dry Bone Tissue Sections for Microscopy
Authors: de Boer H. H. , Aarents M. J. , Maat G. J. R. 
Published: January 2013

ABSTRACTIn the last decade, the use of light microscopy has been firmly established for the investigation of exhumated human bone tissue. As a rule, these remains cannot be decalcified; thus, they are most commonly prepared for microscopic analysis as ground thin sections. These ground sections are of great value in diagnosing disease, in estimating age or in assessing taphonomic alteration. As bone is sometimes fragile and can be damaged by the grinding process, the specimen is occasionally supported by an embedding medium.In contrast to the vast amount of research conducted on embedded and unembedded unstained bone material, the use of histological stains on undecalcified dry bone tissue has been long neglected. In this article, a new method for embedding, sawing and grinding dry bone tissue is presented. The produced sections are subsequently stained with haematoxylin. The results show that even ground sections of fragile bone can be made in a quick and easy manner. Staining these sections enhances the envisioning of micro‐architecture and taphonomical processes. In addition, the sections stay open for inspection under polarized light. The results were consistent throughout the used bone material. To keep the method as accessible and comprehensive as possible, a step‐wise manual is provided. An additional troubleshooting paragraph discusses the most often encountered problems and provides solutions. Copyright © 2011 John Wiley & Sons, Ltd.
Parent's attitude toward prenatal diagnosis and termination of pregnancy could be influenced by other factors rather than by the severity of the condition
Authors: Alsulaiman Ayman , Abu‐Amero Khaled K. 
Published: January 2013

ABSTRACTObjectiveThe aim of this study is to investigate whether the severity of a particular condition alone influences parents' attitudes toward prenatal diagnosis (PND) and termination of pregnancy (TOP) or are there other factors involved?MethodsA questionnaire that mainly focuses on parent's attitude toward PND and TOP for 30 different hypothetical scenarios for a series of genetic, non‐genetic, and non‐medical conditions were completed by 400 Saudi parents. Results were compared and scored and parent comments were noted. Additionally, cross tabulation of thalassemia, considered the most severe and had the most favorable PND and TOP, against the 29 other conditions were carried out to find similarities and different views toward TOP and PND.ResultsWe found that parents' attitudes toward PND and TOP for thalassemia are significantly associated with their attitudes in relation to all of the other conditions (p < 0.01).ConclusionSaudi Parents' attitudes toward TOP and PND are not always influenced by the severity of the condition. © 2013 John Wiley & Sons, Ltd.
Secure hybrid multibit multiplicative watermarking for media distribution over mobile Internet
Authors: Wang Jinwei , Yan Leiming , Han Jin , Wang Yuxiang 
Published: January 2013

AbstractWith the rapid development and rich applications of mobile Internet, security issues become urgent. For example, piracy of media content (image, audio, or video) becomes easier because mobile Internet provides more ways to re‐distribute media contents. Watermarking has been regarded as a potential solution for identifying pirate copies. However, the watermarking algorithms' security and robustness are still not ideal enough for practical applications, especially in mobile scenarios with more attacks. In this paper, a novel hybrid multiplicative watermarking algorithm is proposed to obtain higher security and good robustness. In this algorithm, two embedding rules are changed according to the secret key, which embed the watermark into Discrete Wavelet Transform (DWT) coefficients. The secret key improves the watermark system's security. Additionally, the optimum and locally optimum hybrid multiplicative watermarking decoders are proposed, respectively, to detect the watermark. Because it works with two rules, it obtains a tradeoff in robustness. Various comparative experiments are carried out, and results are given to prove the valid of theoretical analysis. Copyright © 2013 John Wiley & Sons, Ltd.
The feasibility of replacing the sliding scale duty with cotton subsidies in China
Authors: Wang Xuejun , Maeda Koshi , Mao Xuefeng 
Published: January 2013

PurposeThis paper aims to determine whether domestic cotton support permitted by the current or potential World Trade Organization (WTO) rules would be sufficient to compensate the cost to China's cotton farmers if the sliding scale duty (SSD) on cotton imports is removed.Design/methodology/approachThe simulation was conducted using a static spatial equilibrium model (SEM) of the world cotton market. First, a base model was specified to provide a good representation of the world cotton market's conditions. Second, simulations were conducted to evaluate the effects of replacing the SSD and subsidizing cotton producers pursuant to the current or potential WTO rules on domestic cotton support.FindingsThe results of the simulations suggest that China's cotton farmers are bound to incur losses. In either case, cotton subsidies permitted by the current or potential WTO rules are not sufficient to compensate for the cost to China's cotton producers if the SSD is eliminated.Research limitations/implicationsIt should be pointed out that these findings could suffer from a bias, primarily because the authors assumed that the WTO's blue box subsidies have no incentives for farmers to produce, and no substitution between cotton and alternative products. Thus, additional work is needed to reflect a more realistic situation in future studies.Originality/valueThe simulation estimation contributes to a better understanding of the issue of whether China should replace the current SSD with cotton subsidies to protect cotton producers.
Polymorphisms within the COL5A1 3′‐UTR That Alters mRNA Structure and the MIR608 Gene are Associated with Achilles Tendinopathy
Authors: Abrahams Yoonus , Laguette Mary‐Jessica , Prince Sharon , Collins Malcolm 
Published: January 2013

SummaryCOL5A1 encodes for the α1 chain of type V collagen, an important regulator of fibril assembly in tendons, ligaments and other connective tissues. A polymorphism (rs12722) within the functional COL5A1 3′‐untranslated region (UTR) has been shown to associate with chronic Achilles tendinopathy and other exercise‐related phenotypes. The COL5A1 3′‐UTR contains several putative cis‐acting elements including a functional Hsa‐miR‐608 binding site. The aim of this study was to determine whether previously uncharacterized polymorphisms within a functional region of the COL5A1 3′‐UTR or the MIR608 gene are associated with chronic Achilles tendinopathy. The effect of these COL5A1 3′‐UTR polymorphisms on the 3′‐UTR predicted mRNA secondary structure was also investigated. One hundred and sixty Caucasian chronic Achilles tendinopathic and 342 control participants were genotyped for the COL5A1 3′‐UTR markers rs71746744, rs16399 and rs1134170, as well as marker rs4919510 within MIR608. All four genetic markers were independently associated with chronic Achilles tendinopathy. The COL5A1 polymorphisms appear to alter the predicted secondary structure of the 3′‐UTR. We propose that the secondary structure plays a role in the regulation of the COL5A1 mRNA stability and by implication type V collagen production.
Interactive programme to enhance protective factors for eating disorders in girls with type 1 diabetes
Authors: Wilksch Simon M. , Starkey Karina , Gannoni Anne , Kelly Tania , Wade Tracey D. 
Published: January 2013

AbstractAimsThis study evaluated the effectiveness of a pilot programme in enhancing protective factors for eating disorders in young girls with type 1 diabetes (T1D).MethodsTwenty girls with T1D (M age = 11.06 years) attended two 4‐h group sessions. A 4‐week baseline control period was compared against changes at post‐programme and at 1‐month follow‐up on measures of eating disorder risk factors and indicators of glycaemic control.ResultsAt post‐intervention, significant improvements were found for self‐efficacy related to diabetes management, self‐esteem, body‐esteem,thin‐ideal internalization and perfectionism. These gains were maintained at 1‐month follow‐up. Participants were also rated by their parents as assuming more responsibility for specific diabetes‐related tasks at follow‐up.ConclusionsA brief interactive programme can favourably impact protective factors for disordered eating. The development of effective disordered eating prevention strategies for girls with T1D is an urgent priority and the current study is a first step in this direction.
Phosphodiesterase Type 5 Inhibitor Treatment for Erectile Dysfunction in Patients with End-Stage Renal Disease Receiving Dialysis or After Renal Transplantation
Authors: Lasaponara Fedele , Sedigh Omid , Pasquale Giovanni , Bosio Andrea , Rolle Luigi , Ceruti Carlo , Timpano Massimiliano , Negro Carlo Luigi Augusto , Paradiso Matteo , Abbona Annamaria , Segoloni Giuseppe Paolo , Fontana Dario 
Published: January 2013

ABSTRACT

Introduction
The phosphodiesterase type 5 (PDE5) inhibitors are generally well tolerated and effective for treating erectile dysfunction (ED), including in patients with significant comorbidity. Because of this benign safety profile, investigators have used PDE5 inhibitors to treat patients with ED and severe renal disease or those who have received renal transplants.

Aim
To assess safety and efficacy of PDE5 inhibitors in patients receiving dialysis or renal transplants.

Main Outcome Measures
Erectile function as assessed by the International Index of Erectile Function (IIEF) and Global Assessment Questions; adverse events (AEs).

Methods
We reviewed published studies of PDE5 inhibitors in patients receiving dialysis or renal transplants.

Results
In double-blind, placebo-controlled studies in patients receiving dialysis or renal transplants, sildenafil significantly improved erectile function as assessed by the IIEF, and 75–85% of patients reported improved erectile function on Global Assessment Questions; efficacy was more variable in less well-controlled studies. In &gt;260 patients undergoing dialysis who received sildenafil in clinical studies, there were only six reported discontinuations because of AEs (headache [N=3], headache and nausea [N=1], gastrointestinal [N=1], and symptomatic blood pressure decrease [N=1]). In approximately 400 patients with renal transplants who received sildenafil, only three patients discontinued because of AEs. Vardenafil improved IIEF scores of up to 82% of renal transplant recipients in randomized, controlled studies (N=59, total), with no reported discontinuations because of AEs. Limited data also suggest benefit with tadalafil.

Conclusions
ED is common in patients undergoing renal dialysis or postrenal transplant and substantially affects patient quality of life. Sildenafil and vardenafil appear to be efficacious and well tolerated in patients receiving renal dialysis or transplant.
Gastro-protective policy and the incidence of upper gastrointestinal bleeding
Authors: Taha Ali S , Kelly Claire , McCloskey Caroline , Craigen Theresa , Angerson Wilson J 
Published: January 2013

ObjectivesIn recent years, policies have been proposed in order to guide the safer use of non-steroidal anti-inflammatory drugs (NSAIDs) and antiulcer therapy. We aimed to investigate the incidence of upper gastrointestinal bleeding (UGIB) before and after the introduction of these policies, 2007–2009, in a well-defined population in southwest Scotland.MethodsAll patients with non-variceal upper gastrointestinal bleeding (NV-UGIB), diagnosed at a single regional unit, were included. Total drugs prescribed in our population were noted, including antiulcer drugs, antithrombotic drugs and both cyclo-oxygenase-2 enzyme-selective and non-selective inhibiting NSAIDs.ResultsThe incidence, the number of cases per 100 000 population per annum, of NV-UGIB fell from 134.7 in 2007 to 125.1 in 2008, and to 90.3 cases in 2009 (p<0.001). There was also a significant rise in the use of non-selective NSAIDs, proton pump inhibitors and antithrombotic drugs.ConclusionsAlthough a cause-and-effect relationship cannot be fully proven, physician education through drug-use policies is associated with a drop in the incidence of NV-UGIB. This is relevant to the prevention of this common condition.
B-cell Maturation Antigen Is a Promising Target for Adoptive T-cell Therapy of Multiple Myeloma
Authors: Carpenter Robert O. , Evbuomwan Moses O. , Pittaluga Stefania , Rose Jeremy J. , Raffeld Mark , Yang Shicheng , Gress Ronald E. , Hakim Frances T. , Kochenderfer James N. 
Published: January 2013

Abstract
Purpose: Multiple myeloma is a usually incurable malignancy of plasma cells. New therapies are urgently needed for multiple myeloma. Adoptive transfer of chimeric antigen receptor (CAR)–expressing T cells is a promising new therapy for hematologic malignancies, but an ideal target antigen for CAR-expressing T-cell therapies for multiple myeloma has not been identified. B-cell maturation antigen (BCMA) is a protein that has been reported to be selectively expressed by B-lineage cells including multiple myeloma cells. Our goal was to determine if BCMA is a suitable target for CAR-expressing T cells.
Experimental Design: We conducted an assessment of BCMA expression in normal human tissues and multiple myeloma cells by flow cytometry, quantitative PCR, and immunohistochemistry. We designed and tested novel anti-BCMA CARs.
Results: BCMA had a restricted RNA expression pattern. Except for expression in plasma cells, BCMA protein was not detected in normal human tissues. BCMA was not detected on primary human CD34+ hematopoietic cells. We detected uniform BCMA cell-surface expression on primary multiple myeloma cells from five of five patients. We designed the first anti-BCMA CARs to be reported and we transduced T cells with lentiviral vectors encoding these CARs. The CARs gave T cells the ability to specifically recognize BCMA. The anti-BCMA-CAR–transduced T cells exhibited BCMA-specific functions including cytokine production, proliferation, cytotoxicity, and in vivo tumor eradication. Importantly, anti-BCMA-CAR–transduced T cells recognized and killed primary multiple myeloma cells.
Conclusions: BCMA is a suitable target for CAR-expressing T cells, and adoptive transfer of anti-BCMA-CAR–expressing T cells is a promising new strategy for treating multiple myeloma. Clin Cancer Res; 19(8); 2048–60. ©2013 AACR.
CD30 expression defines a novel subgroup of diffuse large B-cell lymphoma with favorable prognosis and distinct gene expression signature: a report from the International DLBCL Rituximab-CHOP Consortium Program Study
Authors: Hu Shimin , Xu-Monette Zijun Y. , Balasubramanyam Aarthi , Manyam Ganiraju C. , Visco Carlo , Tzankov Alexander , Liu Wei-min , Miranda Roberto N. , Zhang Li , Montes-Moreno Santiago , Dybkær Karen , Chiu April , Orazi Attilio , Zu Youli , Bhagat Govind , Richards Kristy L. , Hsi Eric D. , Choi William W. L. , Han van Krieken J. , Huang Qin , Huh Jooryung , Ai Weiyun , Ponzoni Maurilio , Ferreri Andrés J. M. , Zhao Xiaoying , Winter Jane N. , Zhang Mingzhi , Li Ling , Møller Michael B. , Piris Miguel A. , Li Yong , Go Ronald S. , Wu Lin , Medeiros L. Jeffrey , Young Ken H. 
Published: January 2013

Key PointsCD30 expression defines a novel and unique subgroup of DLBCL with favorable clinical outcome and distinct gene expression signature.
Le Logos héraclitéen : l’obscurité de l’ambivalence entre détermination et indétermination
Authors: Cantin-Brault Antoine 
Published: January 2013

C’est un lieu commun de dire d’Héraclite qu’il est obscur, mais d’où vient précisément cette obscurité ? Libérant la métaphysique à partir d’une constitution entendue comme onto-proto-logie, l’obscurité d’Héraclite semble participer à la fois d’une métaphysique déterminante qui cherche à dire l’étant suprême en un Logos totalisant, et d’une métaphysique indéterminante ne voulant que signifier le principe qui se situe au-delà de l’étant. Ces deux tendances sont illustrées par Hegel et Heidegger, en leurs interprétations respectives d’Héraclite ; chacun énonce quelque chose de vrai, sans faire taire l’autre. Héraclite se découvre ainsi au carrefour de perspectives métaphysiques qui se préciseront plus tard, que son obscurité lui permet d’anticiper toutes deux.
Identification of Multivariable Fractional Order Systems
Authors: Djamah Tounsia , Bettayeb Maamar , Djennoune Said 
Published: January 2013

AbstractThis paper deals with identification of multivariable fractional order systems. The state space model is used, based on the Guidorzi canonical form. An output error identification approach is used, and the parametric sensitivity functions model is developed as a multivariable fractional model. Its simulation is carried out using the fractional bounded integration operator. Different simulations test the method efficiency, and its statistical performance is analyzed, using Monte Carlo simulation at various signal‐to‐noise ratios.
Beyond the Business Case: An Ethical Perspective of Diversity Training
Authors: Jones Kristen P. , King Eden B. , Nelson Johnathan , Geller David S. , Bowes‐Sperry Lynn 
Published: January 2013

AbstractExtant literature on diversity training programs continues to yield little evidence of their overall effectiveness. Whereas the most common approach to diversity training entails justifying the value of diversity on the basis of its contribution to the organization's bottom line, we argue that approaching diversity training from an ethical perspective may bolster the effectiveness of traditional approaches. Specifically, to the degree that traditional bottom‐line justifications are enhanced with social justice arguments, training effectiveness will increase. In the following article, we discuss traditional approaches to diversity training, provide a general overview of ethics, discuss how theory and research from behavioral ethics literature might help to address some of the challenges faced in diversity training, and draw from ethics literature to make specific, novel suggestions about the implementation and presentation of diversity training.
The differences of user behavior between forum and Facebook for smoking cessation intervention
Authors: Zhang Mi , Yang Christopher C. 
Published: January 2013

AbstractQuitNet is one of the most popular websites providing tools and services to help people quit smoking. QuitNet developed forums on its original website to help its users interact with each other. It also built a public page on Facebook, which provides another community for people to discuss issues of smoking cessation. This study compares user behaviors between the two communication channels on smoking cessation – QuitNet Forum and QuitNet Facebook. Social network analysis and user response immediacy were used to analyze user behavior on the two channels. It was found that users of QuitNet Forum participated in discussions more actively, while QuitNet Facebook users behaved more differently from each other.