bluuebunny/crossref_metadata_2025_split huggingface dataset:
Validation of a triple‐color pseudovirion‐based neutralization assay for immunogenicity assessment of a 14‐valent recombinant human papillomavirus vaccine
Authors: Gao Shuman , Zhao Dandan , Feng Caixia , Kou Yajuan , Lu Jianbo , Luo Chunxia , Li Xuefeng , Wang Yang , Xie Liangzhi 
Published: August 2024

AbstractValidation of bioanalytical methods is crucial, especially in the pharmaceutical industry, to determine their suitability for specific purposes and the accuracy of analytical results. The pseudovirion‐based neutralization assay (PBNA) is considered the gold standard for detecting and quantifying neutralizing antibodies against human papillomavirus in vaccine development for disease prevention. This paper introduces an improved triple‐color PBNA method, capable of simultaneous detection of two or three human papillomavirus (HPV types for use in the development of a 14‐valent HPV vaccine candidate. The primary objective was to comprehensively validate the triple‐color PBNA method for general vaccine immunogenicity assays. Results show that the method has good specificity, accuracy, precision, linearity, robustness, and applicability. This innovative triple‐color PBNA offers an improved approach for large‐scale immunogenicity assessment in vaccine development. This study lays a solid foundation that can serve as a guiding paradigm for assessing vaccine responses in preclinical and clinical phases, providing valuable insights to the field.
High‐precision peaks‐grabbing modified π‐type model in multi‐laps on‐chip spiral inductors using R–L ladder network
Authors: Chen Haidong , He Lei , Huang He , Xue Quan , Che Wenquan 
Published: August 2024

AbstractParasitic effects significantly interfere with systematic model‐parameter extraction, making linear fitting of spiral inductors challenging when the number of turns exceeds 6, as seen in existing works. Based on the single‐π model, we propose a parameter‐extraction technique using an additional three ladder R–L ladder network in series to more accurately predict skin and proximity effects. Compared to the latest enhanced π‐circuit model, our proposed model with parameter‐extraction technique in multi‐laps inductors accurately predicts the characteristics of series inductance (Leff) and quality factor (Q) across the self‐resonant frequency, especially at the peak. This model could be used directly for the model of the on‐chip inductor in both academic and industrial fields.
A simple sinusoidal curve‐based one‐dimensional periodic leaky‐wave antenna for high‐gain continuous beam scanning
Authors: Pandey Vishakha , Ahmad Ayaz , Mukherjee Jayanta 
Published: August 2024

AbstractA novel technique is presented based on a sinusoidal curve‐shaped one‐dimensional periodic leaky‐wave antenna to eliminate open stopband (OSB) and enhance gain. The radiating stub is inspired by a sinusoidal curve showing zero phase constant at a single broadside frequency (9 GHz) and ripple‐free attenuation constant. The technique is first used on a unit cell with half‐cycle sinusoidal‐curved radiating stub to achieve uniform gain and OSB suppression. Subsequently, to further improve the gain, a unit cell with a full‐cycle sinusoidal‐curved radiating stub with an offset introduced at the centerline is applied. Finally, the full‐cycle sinusoidal stub is modified by introducing a pair of inclined “branching” half‐cycle sinusoidal stubs at an angle θ° from the centerline to further enhance the gain. A 4.65 dB gain improvement is observed along with complete OSB elimination for the proposed design.
Submodular batch scheduling on parallel machines
Authors: Sun Tao , Wang Jun‐Qiang , Fan Guo‐Qiang , Liu Zhixin 
Published: August 2024

AbstractThis article studies a submodular batch scheduling problem motivated by the vacuum heat treatment. The batch processing time is formulated by a monotone nondecreasing submodular function characterized by decreasing marginal gain property. The objective is to minimize the makespan. We show the NP‐hardness of the problem on a single machine and of finding a polynomial‐time approximation algorithm with the worst‐case performance ratio strictly less than for the problem on parallel machines. We introduce a bounded interval to model the batch processing time using two parameters, that is, the total curvature and the quantization indicator. Based on the decreasing marginal gain property and the two parameters, we make a systematic analysis of the full batch longest processing time algorithm and the longest processing time greedy algorithm, and propose the instances with the bound of batch capacity for these two algorithms for the submodular batch scheduling problem. Moreover, we prove the submodularity of batch processing time function of the existing batch models including the parallel batch, serial batch, and mixed batch models. We compare the worst‐case performance ratios in the existing batch models with those deduced from our work in the submodular batch model. In most situations, the worst‐case performance ratios deduced from our work are comparable to the best‐known worst‐case performance ratios with tailored examinations.
Practical diagnosis and treatment of premenstrual syndrome and premenstrual dysphoric disorder by psychiatrists and obstetricians/gynecologists in Japan
Authors: Yoshimi Kana , Inoue Fumi , Odai Tamami , Shirato Nahoko , Watanabe Zen , Otsubo Tempei , Terauchi Masakazu , Takeda Takashi 
Published: August 2024

AbstractAimTo investigate and compare the diagnoses and treatment of premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD) from the perspectives of psychiatrists and obstetricians/gynecologists (OB/GYNs) in Japan.MethodsBetween December 2021 and February 2022, a web‐based survey was conducted among the members of the Japanese Association of Neuro‐Psychiatric Clinics. Data from 262 psychiatrists who responded to the aforementioned survey were compared with data from 409 OB/GYNs from a survey conducted in 2021 among members of the Japanese Society of Obstetrics and Gynecology.ResultsOverall, 79.8% of psychiatrists and 97.3% of OB/GYNs were involved in practicing PMS/PMDD diagnosis and treatment. Most psychiatrists believed that PMS should be treated by OB/GYNs (74.4%) and PMDD by psychiatrists (75.6%). Only vague medical interviews were conducted by 86.6% of psychiatrists, and only 9.7% maintained a two‐cycle symptom diary. Psychiatrists mostly prescribed selective serotonin/serotonin and noradrenaline reuptake inhibitor (SSRI/SNRI) continuous dosing (91.1%), followed by Kampo medicines, especially Kamishoyosan (73.3%); only 2.8% chose oral contraceptive pills, unlike OB/GYNs, while SSRI continuous (32.8%) and luteal phase dosing (20.6%) and Kampo medicine (42.1%) were the most common first‐line treatments. Lifestyle guidance was prescribed by 63.6% of psychiatrists, followed by cognitive behavioral therapy (13.8%) and the symptom diary observation method (11.1%), which were similar to OB/GYNs' choices.ConclusionsMany Japanese psychiatrists and OB/GYNs do not base PMS/PMDD diagnoses on prospective monitoring methods using specific diagnostic criteria and therefore do not provide evidence‐based treatment. Moreover, a tendency of being biased toward treatments in which the department specialized was observed.
Synthesis of acrylate copolymer‐based super oil adsorption resins and their performances
Authors: Zhou Feng , Song Yu , Li Yu , Ren Xianyan 
Published: August 2024

AbstractIn this paper, an acrylate copolymer‐based oil adsorption resin was designed and synthesized by a suspension polymerization with octadecyl acrylate (SA) and butyl acrylate (BA) as monomers, divinylbenzene (DVB) as a cross‐linking agent, and toluene as a pore‐forming agent. By studying the synthesis conditions, the copolymer “SA‐BA‐DVB” (PSBA) with the best adsorption capacity was obtained, when the molar ratio between SA and BA was about 0.9, the content of the DVB and PVA 1788 was about 0.107 wt% and 1.0 wt%, respectively, accounting for the total mass amount of the monomers. Furthermore, by introducing 2% reactive silica nanoparticles (R‐SiO2), the performances of the PSBA were improved due to its increased hydrophobicity and activity space. The equilibrium adsorption capacity of the resulted R‐SiO2/PSBA to kerosene, diesel oil, benzene, and p‐xylene was 31.90, 34.13, 39.44, and 41.81 mL/g, respectively, which is about 1.12 to 1.21 times higher than that of the PSBA. Also, the R‐SiO2/PSBA show brilliant oil retention rate of about 99% after centrifugation at 3000 rpm for 5 min and recycling ability which can be reusable for at least 10 absorption‐desorption cycles without capacity change, demonstrating that the obtained R‐SiO2/PSBA resin can be used as oil removing agents in the field of oil spill applications.Highlights
R‐SiO2 modified acrylate copolymer as an oil adsorption resin was designed and synthesized.
The influence of the monomers, cross‐linking agent, and others on the adsorption resin was systematically studied.
The adsorption kinetics and performances of the adsorption resin were studied.
Generation of state‐dependent ensemble perturbations based on time‐varying seawater density for GloSea5 initialization
Authors: Lee Jeong‐Gil , Ham Yoo‐Geun , Kim Ji‐Gwang , Chang Pil‐Hun 
Published: August 2024

AbstractIn this study, we developed a flow‐dependent oceanic initialization system for initializing the oceanic temperature and salinity in the Global Seasonal forecast system version 5 (GloSea5). Our algorithm overcomes the limitation of stationary perturbations for Ensemble Optimal Interpolation (EnOI) by spreading observed information along isopycnal lines to create three‐dimensional snapshot density states. The proposed algorithm, which we call state‐dependent ensemble‐based EnOI (SD‐EnOI), takes into account changes in the background error covariance over time without relying on ensemble model simulations. To evaluate the quality of the oceanic initial conditions (ICs) produced by SD‐EnOI, we compared them with those generated by the Global Ocean Data Assimilation and Prediction System version 1 (GODAPS1) operated by the Korea Meteorological Agency (KMA) throughout January 2017 to December 2017. Our findings show that the thermal construction of the SD‐EnOI ICs is more realistic than that of GODAPS1, particularly in the tropical Pacific region. The strong warm bias in sea surface temperature (SST) and the shallow mixed‐layer depth bias observed in the GODAPS1 ICs are not shown in SD‐EnOI. Due to the more realistic oceanic thermal structure present in the SD‐EnOI ICs, their use in retrospective forecast experiments resulted in a systematic reduction in climatological SST drift in the central‐eastern Pacific for forecasts up to four lead months compared to using GODAPS1 ICs. This demonstrates the significant impact of the initialization process on the quality of dynamical seasonal forecasts.
Data‐driven adaptive resilient funnel consensus tracking of multiagent systems under jamming attacks
Authors: Sun Shan‐Shan , Li Yuan‐Xin 
Published: August 2024

AbstractIn this article, we investigate a model‐free adaptive funnel control framework for nonlinear multiagent systems under jamming attacks. An equivalent time‐varying linear data model is built for agents by utilizing the dynamic linearization approach. Then, a predefined funnel function is presented such that the tracking errors are expected to evolve within a predetermined range. The transient and steady‐state behaviors of the tracking error can be improved by adjusting the parameter values of the funnel function. Moreover, the Stackelberg game is employed to determine the optimal transmission power between the transmitters and jammers considering the state of the transmission channel, which influences the jamming attack rate. Based on funnel control, a model‐free adaptive funnel control scheme is presented to guarantee that the tracking error remains within a funnel boundary (even in the presence of jamming attacks) and the transient and steady‐state performances are improved. The effectiveness of the proposed algorithm is further demonstrated through simulations.
An advanced robust integral reinforcement learning scheme with the fuzzy inference system
Authors: Liu Ao , Wang Ding , Qiao Junfei 
Published: August 2024

AbstractIn this paper, the model‐free robust control problem is investigated for nonlinear systems with a relaxed condition of initial admissible control. An advanced integral reinforcement learning method is developed, which merges the adaptive network‐based fuzzy inference system (ANFIS) and pre‐training of the initial weights. To loose the condition for choosing the initial control law, pre‐training of initial weights is established by utilizing the ANFIS to provide the information corresponding to the system model, which is applicable to the model‐free issue. Based on the actor‐critic structure, the approximate optimal control law is obtained by employing adaptive dynamic programming. Redesigning the obtained control law, the robust controller can be derived to stabilize the system with the uncertain term. Eventually, two examples are utilized to verify the effectiveness of the constructed algorithm.
Acute Generalised Exanthematous Pustulosis Associated with Upadacitinib Treatment
Authors: Banda Thandiwe , Butt Sanaa , Maheshwari Madhavi , Chattopadhyay Moumita 
Published: August 2024

Abstract
Acute generalised exanthematous pustulosis (AGEP) is a rare drug-induced pustular eruption characterised by the rapid onset of superficial pinhead pustules. We discuss the case of a 27-year-old man who presented with a generalised pustular eruption on the neck, trunk and limbs. He commenced upadacitinib for the treatment of atopic dermatitis (AD) 6 months before developing the rash, and the dose was increased from 15 to 30 mg daily, 3 months prior. His only other medication was oral terbinafine, for suspected tinea corporis, which was initiated 1 month before developing the pustular eruption. Laboratory investigations showed a mildly raised CRP 25 mg/L, neutrophilia 8.22 10 × 9/L, and a mildly raised ALT 46 U/L. A skin biopsy showed subcorneal pustules and a few scattered keratinocytes. Upadacitinib and terbinafine were suspended and the pustular eruption resolved. Updacitinib was reintroduced 3 weeks later as the rash was thought to be due to terbinafine and the rash recurred. He was diagnosed with AGEP secondary to upadacitinib. Upadacitinib is a selective JAK inhibitor that is increasingly used for the management of AD and clinicians should be aware that AGEP is a rare but severe adverse effect.
An analytical solution for shear bearing capacity of circumferential joints of precast concrete segmental tunnel linings considering dowel action
Authors: Amjad Rizwan , Zhang Yumeng , Liu Xian 
Published: August 2024

AbstractThe capacity of the circumferential joint of the precast concrete segmental tunnel lining (PCTL) structure in terms of shear performance principally includes the dowel action by connector/bolt as well as friction force, and it is a vital parameter to assess the mechanical response of the circumferential joint. Further, as there was no analytical model available for precise estimation of a circumferential joint in terms of the shear‐bearing capacity considering the dowel action of the bolt in the presence of axial/normal force, therefore in this investigation, an analytical model has been proposed to estimate the shear‐bearing capacity of the circumferential joint. Furthermore, the analytical model's precision and accuracy were validated via large‐scale experimental investigation on a circumferential joint of PCTL. Upon comparing analytical model outcomes with experimental results, absolute error varied between +5% and −9%, with an average value of the coefficient of friction at the yield point of the bolt. Moreover, the formation of hinges on the side of the bolt within the segment was considered a failure of the circumferential joint. Additionally, the parametric investigation revealed that with just a 1% change in axial force, the diameter, pre‐tightening, and yield strength of the bolt and concrete strength improved by 2.85%, 1%, 0.27%, 0.26% and 0.17% shear‐bearing capacity of the circumferential joint respectively. Axial force variation greatly influences the shear‐bearing capacity of circumferential joint followed by diameter, pre‐tightening, yield strength of the bolt, and concrete strength. Conclusively, with analysis of axial force distribution around the ring for the tunnel, the proposed model has been applied to a full ring to estimate shear bearing capacity.
Structure Design of a Four‐Pillar Magnetically Integrated Fractional‐Turn Planar Transformer and its Loss Analysis
Authors: Wang Pengxiang , Cao Haichuan , Xiao Jian 
Published: August 2024

AbstractIn the field of high‐frequency transformers, winding losses and core losses constrain the improvement of the power density of planar transformers. Reducing losses on the AC resistor and losses on the core is the key to improving the energy transfer efficiency of planar transformers. Aiming at the half‐bridge LLC resonant converter, this paper proposes a novel structure of a four‐pillar magnetically integrated fractional‐turn planar transformer. In terms of the core structure, according to the principle of magnetic integration, integrate four discrete magnetic cores into a single core, effectively reducing the core volume, so reduces core losses. In the winding, the secondary winding for half‐turn structure, compared with the traditional planar transformer, the primary winding and the secondary winding turns ratio from n:1 to 0.5n:0.5, the primary winding and secondary winding loss reduced to the original 1 of 2. The secondary side windings are combined with the windings of the same current direction by suitable arrangement. By increasing the current path, effectively reduces the problem of uneven distribution of current density in the winding and reduces the AC losses on the winding. © 2024 Institute of Electrical Engineers of Japan and Wiley Periodicals LLC.
Constraining Asymmetric Dark Matter using colliders and direct detection
Authors: Roy Arnab , Dasgupta Basudeb , Guchait Monoranjan 
Published: August 2024

Abstract
We reappraise the viability of asymmetric dark matter (ADM) realized as a Dirac fermion coupling dominantly to the Standard Model fermions. Treating the interactions of such a DM particle with quarks/leptons in an effective-interactions framework, we derive updated constraints using mono-jet searches from the Large Hadron Collider (LHC) and mono-photon searches at the Large Electron-Positron (LEP) collider. We carefully model the detectors used in these experiments, which is found to have significant impact. The constraint of efficient annihilation of the symmetric part of the ADM, as well as other observational constraints are synthesized to produce a global picture. Consistent with previous work, we find that ADM with mass in the range 1–100 GeV is strongly constrained, thus ruling out its best motivated mass range. However, we find that leptophilic ADM remains allowed for ≳ 10 GeV DM, including bounds from colliders, direct detection, and stellar heating. We forecast that the Future Circular Collider for electron-positron collisions (FCC-ee) will improve sensitivity to DM-lepton interactions by almost an order of magnitude.
Lorentz violating backgrounds from quadratic, shift-symmetric, ultralight dark matter
Authors: Jiang Minyuan , Pecjak Benjamin D. , Perez Gilad , Sankaranarayanan Somasundaram 
Published: August 2024

Abstract
We consider an effective theory for a shift-symmetric, quadratically-coupled, ultralight spin-0 field. The leading CP conserving interactions with Standard Model fields in the effective theory arise at dimension 8. We discuss the renormalization group evolution and positivity bounds on these operators, as well as their possible UV origins. Assuming that the spin-0 field is associated with an ultralight dark matter candidate, we discuss the effects of the dimension-8 operators on experiments searching for the oscillation of fundamental constants and Lorentz violation. We find that the direct bounds on these two effects are of similar strength but rather weak, corresponding to a UV cutoff scale of keV order, as they are mediated by dimension-8 operators.
Mineralogy, mineral chemistry, and genesis of Cu-Ni-As-rich ores at Lisheen, Ireland
Authors: Frenzel Max , Röhner Markus , Cook Nigel J. , Gilbert Sarah , Ciobanu Cristiana L. , Güven John F. 
Published: August 2024

AbstractThe Irish Orefield is characterised by the presence of both Zn-Pb- and Cu-Ni-As-rich deposits, prospects, and orebodies in similar structural and stratigraphic positions. However, the genetic relationships between these mineralisation types are still debated. In this article, we present new mineralogical, paragenetic, and mineral-chemical observations from the Cu-Ni-As-rich ores at the classic Lisheen deposit, County Tipperary. These observations indicate the intimate association and cogenetic nature of these ores with the more abundant Zn-Pb-rich mineralisation. Specifically, both mineralisation types appear to have formed at the same time, under similar physicochemical conditions, and from the same ore fluids. In addition, both types of mineralisation contain elevated Ge contents. The cogenetic nature of the two mineralisation types, the relative absence of Cu-Ni-As-rich ores from most of the larger Irish-type Zn-Pb deposits compared to expectations derived from probable ore fluid compositions, and finally, the known geological characteristics of larger Cu-Ni-As-rich ore bodies, like Gortdrum, indicate that significant Cu-Ni-As-rich mineralisation could be present at lower stratigraphic levels across the Irish Orefield. Areas with extensive known Zn-Pb mineralisation are expected to be particularly prospective for such ores, which may occur at stratigraphic levels as deep as the Old Red Sandstone. This may have additional implications beyond Ireland, and could point to the potential for undiscovered Cu-rich ores in low-temperature carbonate-hosted Zn-Pb districts elsewhere.
Standardized template for clinical reporting of PSMA PET/CT scans
Authors: Esfahani Shadi A. , Morris Michael J. , Sartor Oliver , Frydenberg Mark , Fanti Stefano , Calais Jeremie , Vapiwala Neha 
Published: August 2024

Abstract
Purpose
Accurate diagnosis and staging of prostate cancer are crucial to improving patient care. Prostate-specific membrane antigen (PSMA)-targeted positron emission tomography with computed tomography (PET/CT) imaging has demonstrated superiority for initial staging and restaging in patients with prostate cancer. Referring physicians and PET/CT readers must agree on a consistent communication method and application of information derived from this imaging modality. While several guidelines have been published, a single PSMA PET/CT reporting template has yet to be widely adopted. Based on the consensus from community and academic physicians, we developed a standardized PSMA PET/CT reporting template for radiologists and nuclear medicine physicians to report and relay key imaging findings to referring physicians. The aim was to improve the quality, clarity, and utility of imaging results reporting to facilitate patient management decisions.

Methods
Based on community and expert consensus, we developed a standardized PSMA PET/CT reporting template to deliver key imaging findings to referring clinicians.

Results
Core category components proposed include a summary of any prior treatment history; presence, location, and degree of PSMA radiopharmaceutical uptake in primary and/or metastatic tumor(s), lesions with no uptake, and incidentally found lesions with positive uptake on PET/CT.

Conclusions
This article provides recommendations on best practices for standardized reporting of PSMA PET/CT imaging. The generated reporting template is a proposed supplement designed to educate and improve data communication between imaging experts and referring physicians.