bluuebunny/crossref_metadata_2025_split huggingface dataset:
How well are we controlling falls from height in construction? Experiences of union carpenters in Washington State, 1989–2008
Authors: Lipscomb Hester J. , Schoenfisch Ashley L. , Cameron Wilfrid , Kucera Kristen L. , Adams Darrin , Silverstein Barbara A. 
Published: August 2013

AbstractBackgroundFalls from height (FFH) continue to cause significant morbidity and mortality across the construction industry.MethodsBy linking data on work hours with workers' compensation records, rates of work‐related injuries resulting from FFH and associated days away from work were evaluated among a large cohort (n = 24,830) of union carpenters in Washington State from 1989 to 2008. Using Poisson regression we assessed rates of FFH over the 20‐year period while adjusting for temporal trend in other work‐related injuries. Patterns of paid lost days (PLDs) were assessed with negative binomial regression.ResultsCrude rates of FFH decreased 82% over the 20‐year period. Reductions were more modest and without demonstrable change since 1996 when adjusting for the temporal reduction in other injuries. Younger workers had higher injury rates; older workers lost more days following falls. Rates of PLDs associated with falls decreased over time, but there was not a consistent decline in mean lost days per fall.ConclusionThese patterns are consistent with decreased FFH for several years surrounding state (1991) and then federal (1994) fall standards; the decline during this time period exceeded those seen in injury rates overall in this cohort. While crude rates of FFH have continued to decline, the decline is not as substantial as that seen for other types of injuries. This could reflect a variety of things including more global efforts designed to control risk (site planning, safety accountability) and changes in reporting practices. Am. J. Ind. Med. 57:69–77, 2014. © 2013 Wiley Periodicals, Inc.
Development of a novel fluorescent protein construct by genetically fusing green fluorescent protein to the N‐terminal of aspartate dehydrogenase
Authors: Ozyurt Canan , Evran Serap , Telefoncu Azmi 
Published: August 2013

AbstractWe developed a fluorescent protein construct by genetically fusing green fluorescent protein (GFP) to aspartate dehydrogenase from Thermotoga maritima. The fusion protein was cloned, heterologously expressed in Escherichia coli cells, and purified by Ni‐chelate affinity chromatography. It was then introduced into a measurement cuvette to monitor its fluorescence signal. Aspartate dehydrogenase functioned as the biorecognition element, and aspartate‐induced conformational change was converted to a fluorescence signal by GFP. The recombinant protein responded to l‐aspartate (l‐Asp) linearly within the concentration range of 1–50 mM, and it was capable of giving a fluorescence signal in 1 Min. Although a linear response was also observed for l‐Glu, the fluorescence signal was 2.7 times lower than that observed for l‐Asp. In the present study, we describe two novelties: development of a genetically encoded fluorescent protein construct for monitoring of l‐Asp in vitro, and employment of aspartate dehydrogenase scaffold as a biorecognition element. A few genetically encoded amino‐acid biosensors have been described in the literature, but to our knowledge, a protein has not been constructed solely for determination of l‐Asp. Periplasmic ligand binding proteins offer high binding affinity in the micromolar range, and they are frequently used as biorecognition elements. Instead of choosing a periplasmic l‐Asp binding protein, we attempted to use the substrate specificity of aspartate dehydrogenase enzyme.
Design and evaluation of radiolabeled tracers for tumor imaging
Authors: Wållberg Helena , Ståhl Stefan 
Published: August 2013

AbstractThe growing understanding of tumor biology and the identification of tumor‐specific genetic and molecular alterations, such as the overexpression of membrane receptors and other proteins, allows for personalization of patient management using targeted therapies. However, this puts stringent demands on the diagnostic tools used to identify patients who are likely to respond to a particular treatment. Radionuclide molecular imaging is a promising noninvasive method to visualize and characterize the expression of such targets. A number of different proteins, from full‐length antibodies and their derivatives to small scaffold proteins and peptide receptor‐ligands, have been applied to molecular imaging, each demonstrating strengths and weaknesses. Here, we discuss the concept of molecular targeting and, in particular, molecular imaging of cancer‐associated targets. Additionally, we describe important biotechnological considerations and desired features when designing and developing tracers for radionuclide molecular imaging.
Experiences in developing labs for a supervisory control and data acquisition course for undergraduate Mechatronics education
Authors: Senk Ivana , Ostojic Gordana , Jovanovic Vukica , Tarjan Laslo , Stankovski Stevan 
Published: August 2013

ABSTRACTThis paper describes the course Systems for Supervision and Process Visualization that is conducted at the undergraduate studies of Mechatronics at University of Novi Sad, the scope, tasks, labs and hands on activities. In addition, it presents the student evaluation of the course that provided valuable feedback for further improvements. © 2013 Wiley Periodicals, Inc. Comput Appl Eng Educ 23:54–62, 2015; View this article online at wileyonlinelibrary.com/journal/cae; DOI 10.1002/cae.21578
Highly Active and Stable Lanthanum‐doped Core–Shell‐structured Ni@SiO2 Catalysts for the Partial Oxidation of Methane to Syngas
Authors: Li Lei , Yao Yao , Sun Bo , Fei Zhaoyang , Xia Hao , Zhao Jing , Ji Weijie , Au Chak‐Tong 
Published: August 2013

AbstractThe nanostructures of silica‐encapsulated NiO nanoparticles (NPs) doped with La, Ce, Ba, Co, Cu, and Fe were prepared and tested as catalysts for the partial oxidation of methane to syngas. Techniques that include TEM, XRD, Brunauer–Emmett–Teller (BET), X‐ray photoelectron spectroscopy (XPS), H2 temperature‐programmed reduction (TPR), and O2 temperature‐programmed oxidation (TPO) were employed to characterize the fresh and used catalysts to understand the structure–performance relationship. The La‐doped Ni@SiO2 catalyst is superior to those doped with other elements. The effect of the reaction conditions on the catalyst performance over the best catalyst were also studied. The La2O3 species that were distributed uniformly throughout the NiO or Ni cores not only modify the core surfaces, but also enhance the resistance toward surface coking, which results in superior catalyst activity and durability.
ChemInform Abstract: Synthesis and Crystal Chemistry of the Fast Li‐Ion Conductor Li7La3Zr2O12 Doped with Fe.
Authors: Rettenwander Daniel , Geiger Charles A. , Amthauer Georg 
Published: August 2013

AbstractThe title compound is synthesized by sintering of Li2CO3, La2O3, ZrO2, and Fe2O3 in air (Pt crucible, 1100 °C, 17 h).
ChemInform Abstract: Ferromagnetism and the Formation of Interlayer As2 Dimers in Ca(Fe1‐xNix)2As2.
Authors: Pobel Roman , Frankovsky Rainer , Johrendt Dirk 
Published: August 2013

AbstractPolycrystalline Ca(Fe1‐xNix)2As2 (x = 0—1) is prepared by solid state reaction of a stoichiometric mixture of the elements (alumina crucible in a sealed silica tube, 1.
ChemInform Abstract: Pd‐Catalyzed Decarboxylative Cross‐Coupling of Perfluorobenzoic Acids with Simple Arenes.
Authors: Luo Hai‐Qing , Dong Wen , Loh Teck‐Peng 
Published: August 2013

AbstractThe ligand‐free reaction allows a simple and efficient access to various polyfluorinated biphenyl structures.
ChemInform Abstract: Cu(I)/TEMPO‐Catalyzed Aerobic Oxidative Synthesis of Imines Directly from Primary and Secondary Amines under Ambient and Neat Conditions.
Authors: Huang Bo , Tian Haiwen , Lin Shoushuai , Xie Meihua , Yu Xiaochun , Xu Qing 
Published: August 2013

AbstractOptimized conditions are developed for the oxidative dimerization of primary amines to yield imine products.
ChemInform Abstract: Solid‐Supported Ru(0) Nanoparticles: An Efficient Ligand‐Free Heterogeneous Catalyst for Aerobic Oxidation of Benzylic and Allylic Alcohol to Carbonyl.
Authors: Das Pralay , Aggarwal Nidhi , Guha Nitul Ranjan 
Published: August 2013

AbstractRu nanoparticles immobilized on Amberlite IRA 900 can be used for various benzylic alcohols.
ChemInform Abstract: Palladium N‐Heterocyclic Carbene Catalysts for the Ultrasound‐Promoted Suzuki—Miyaura Reaction in Glycerol.
Authors: Azua Arturo , Mata Jose A. , Heymes Pauline , Peris Eduardo , Lamaty Frederic , Martinez Jean , Colacino Evelina 
Published: August 2013

AbstractNovel palladium N‐heterocyclic carbene‐based complexes with 3,4,5‐trimethoxybenzyl, alkyl and sulfonate N‐substituents are synthesized and used as pre‐catalysts in the title reaction.
ChemInform Abstract: Ligand‐Accelerated Iron‐ and Cobalt‐Catalyzed Cross‐Coupling Reactions Between N‐Heteroaryl Halides and Aryl Magnesium Reagents.
Authors: Kuzmina Olesya M. , Steib Andreas K. , Markiewicz John T. , Flutbacher Dietmar , Knochel Paul 
Published: August 2013

AbstractIt is demonstrated that catalytic amounts of isoquinoline or quinoline efficiently accelerate the FeCl3‐catalyzed coupling reactions.
ChemInform Abstract: Corrigendum: Indium‐Catalyzed Cycloisomerizations of Cyclopropene‐3,3‐dicarbonyl Compounds: Efficient Access to Benzo‐Fused Heteroaromatics and Heterobiaryls.
Authors: Phun Lien H. , Aponte‐Guzman Joel , France Stefan 
Published: August 2013

AbstractThe cyclopropenes (III) cannot be isolated.
ChemInform Abstract: Magnesium Bromide and Magnesium Chloride Hexahydrate Catalyzed One‐Pot Synthesis of Dihydropyrimidines via Biginelli Reaction under Solvent‐Free Conditions.
Authors: Guelten Sirin 
Published: August 2013

AbstractThree methods are examined for the title reaction whereas, best results are achieved using MgBr2 as catalyst under neat conditions.
ChemInform Abstract: Synthesis of Cyclic 1‐Alkenylboronates via Zr‐Mediated Double Functionalization of Alkynylboronates and Sequential Ru‐Catalyzed Ring‐Closing Olefin Metathesis.
Authors: Nishihara Yasushi , Suetsugu Masato , Saito Daisuke , Kinoshita Megumi , Iwasaki Masayuki 
Published: August 2013

AbstractSeveral subsequent transformations of the alkenylboronates are exemplified.
ChemInform Abstract: Iron‐Catalyzed Borylation of Arenediazonium Salts to Give Access to Arylboron Derivatives via Aryl(amino)boranes at Room Temperature.
Authors: Marciasini Ludovic D. , Richy Nicolas , Vaultier Michel , Pucheault Mathieu 
Published: August 2013

AbstractDirect coupling between aryldiazonium salts (I) and diisopropylaminoborane is catalyzed by ferrocene leading to the formation of a C—B bond.The obtained aryl(amino)boranes can be easily transformed into boronic acids, boronates or borates.
ChemInform Abstract: Iodine‐Mediated Highly Regio‐ and Stereoselective Iodoamination of Ferrocenyl Allene: An Approach for the Synthesis of Ferrocene‐Containing Allylic Amines.
Authors: Chen Shufeng , Yan Qing , Zhao Haiying , Li Baoguo 
Published: August 2013

AbstractA straightforward and efficient method to prepare ferrocene‐containing allylic amines with excellent regio‐ and stereoselectivity is reported.
ChemInform Abstract: An Efficient Copper Catalyzed One‐Pot, Four‐Component and Diastereoselective Synthesis of Highly Functionalized Ferrocenyl Azetidinimines.
Authors: Gouthaman Siddan , Shanmugam Ponnusamy , Mandal Asit Baran 
Published: August 2013

AbstractTreatment of ferrocenyl imines, readily available from ferrocenealdehyde and amines as the starting components, with terminal alkynes and tosyl azide permits a simple synthesis of the target compounds with good diastereoselectivity.
ChemInform Abstract: Uncommon Perspectives in Palladium‐ and Copper‐Catalyzed Arylation and Heteroarylation of Terminal Alkynes Following Heck or Sonogashira Protocols: Interactions Copper/Ligand, Formation of Diynes, Reaction and Processes in Ionic Liquids
Authors: Hierso Jean‐Cyrille , Beauperin Matthieu , Saleh Samer , Job Andre , Andrieu Jacques , Picquet Michel 
Published: August 2013

AbstractReview: 38 refs.
The Upside of Downsizing: Asymmetric Trifunctional Organocatalysts as Small Enzyme Mimics for Cooperative Enhancement of Both Rate and Enantioselectivity With Regulation
Authors: Liu Fei 
Published: August 2013

ABSTRACTSmall molecule organic catalysts (organocatalysts) are widely used in asymmetric catalysis and synthesis. Compared to their enzymatic and transition‐metal counterparts, organocatalysts have advantages in catalytic scope and efficiency but are more limited in proficiency. Chiral trifunctional organocatalysts, in which multiple catalytic motifs act cooperatively on a chiral scaffold, are an emerging class of organocatalysts with improved proficiency. Cooperativity design that enables both enantioselectivity and rate enhancement is essential to developing future generations of organocatalysts in biomimetic asymmetric catalysis. Chirality 25:675–683, 2013. © 2013 The Authors. Chirality published by Wiley Periodicals, Inc.
Chirality: A Relational Geometric‐Physical Property
Authors: Gerlach Hans 
Published: August 2013

ABSTRACTThe definition of the term chirality by Lord Kelvin in 1893 and 1904 is analyzed by taking crystallography at that time into account. This shows clearly that chirality is a relational geometric‐physical property, i.e., two relations between isometric objects are possible: homochiral or heterochiral. In scientific articles the relational term chirality is often mistaken for the two valued measure for the individual (absolute) sense of chirality, an arbitrary attributive term. Chirality 25:684–685, 2013. © 2013 Wiley Periodicals Inc.
Electrocatalysis on Shape‐Controlled Titanium Nitride Nanocrystals for the Oxygen Reduction Reaction
Authors: Dong Youzhen , Wu Yongmin , Liu Mengjia , Li Jinghong 
Published: August 2013

AbstractThe high price of platinum (Pt)‐based cathode catalysts for the oxygen reduction reaction (ORR) have slowed down the practical application of fuel cells. Thanks to their low cost, and outstanding, stable catalytic properties, titanium nitrides (TiN) are among the most promising non‐precious metal electrocatalysts for replacing Pt. However, the shape–activity relationships of TiN electrocatalysts have not been well‐studied or understood up to now. In this work, by simply adjusting the shape of TiO2 precursor, we are able to tailor the morphology of the TiN catalysts from nanoparticles to nanotubes. We have synthetized uniform carbon‐coated titanium nitride nanotubes (carbon‐coated TiN NTs) through a nitridation reaction in NH3 flow using a TiO2 nanotubes/melamine mixture as precursor. The carbon‐coated TiN NTs hybrids exhibit excellent electrocatalytic activity for the ORR, coupled with superior methanol tolerance and long‐term stability in comparison to commercial Pt/C, through an efficient four‐electron‐dominant ORR process. Compared with nanoparticles, the one‐dimensional and hollow structure of the nanotubes result in greater diffusion of electrolyte and superior electrical conductivity, and contribute to the greatly improved electrocatalytic performance of the carbon‐coated TiN NTs nanocomposites.
Role of Edge Atoms in the Hysteretic Behaviour of 3D Spin Crossover Nanoparticles Revealed by an Ising‐Like Model
Authors: Chiruta Daniel , Linares Jorge , Dimian Mihai , Alayli Yasser , Garcia Yann 
Published: August 2013

AbstractWe have applied a phenomenological two‐level Ising‐like model to study the case of 3D coordination polymers showing strongly cooperative but incomplete spin‐transition behaviour. Our numerical results focus on nanoparticles of the cyanide‐bridged 3D network Fe(pyrazine)[Pt(CN)4], considering several factors (i.e. temperature, pressure), the role of short‐ and long‐range interactions and the system size. To be consistent with the experimental studies on a nanometric scale, we used a semiexact method (Monte Carlo entropic sampling) to solve a system that contains molecules on each surface in the high‐spin state (edge atoms). A preliminary analysis of the short‐range antiferromagnetic case has been carried out to illustrate the three‐step transition case.
Phyllosilicates formation in faults rocks: Implications for dormant fault‐sealing potential and fault strength in the upper crust
Authors: Cavailhes Thibault , Soliva Roger , Labaume Pierre , Wibberley Christopher , Sizun Jean‐Pierre , Gout Claude , Charpentier Delphine , Chauvet Alain , Scalabrino Bruno , Buatier Martine 
Published: August 2013

AbstractPhyllosilicate content and related permeability of fault zones form primary controls on hydraulic and mechanical behavior of the brittle crust. Hence, understanding and predicting the localization of these ubiquitous minerals is a major issue for fundamental and applied geosciences. We describe normal fault zones cutting a foreland arkosic turbiditic formation suffering high‐T diagenesis and formed under conditions (~200°C) typical of deeply buried reservoirs and common within the seismogenic interval. Microstructural analyses show a large proportion of phyllosilicates (up to 34%) in the fault rock, derived from near‐complete feldspar alteration and disaggregation during deformation. This study shows that even faults with offsets (~20 cm) much lower than bed thickness can have such large feldspar‐to‐phyllosilicate transformation ratios, implying that the origin of the phyllosilicates is purely transformation related. These results imply that the potential sealing capacity and strength of faults could be predicted from the host rock feldspar content. Where sealing capacity and fault strength can be related to phyllosilicate content, these properties can then also be inferred from the predicted phyllosilicate content: this opens up new horizons concerning the hydraulic and the mechanical behavior of the upper crust.
Using computational strategies to predict potential drugs for nasopharyngeal carcinoma
Authors: Lan Ming‐Ying , Yang Wu‐Lung R. , Lin Kuan‐Ting , Lin Jin‐Ching , Shann Yih‐Jyh , Ho Ching‐Yin , Huang Chi‐Ying F. 
Published: August 2013

AbstractBackgroundNasopharyngeal carcinoma (NPC) is a unique cancer. Refinement of current therapy by discovering potential drugs may be approached by several computational strategies.MethodsWe collected NPC genes from published microarray data and the literature. The NPC disease network was constructed via a protein‐protein interaction (PPI) network. The Connectivity Map (CMap) was used to predict potential chemicals, and support vector machines (SVMs) were further utilized to classify the effectiveness of tested drugs against NPC using their gene expression from CMap.ResultsA highly interconnected network was obtained. Several chemically sensitive genes were identified and 87 drugs were predicted with the potential for treating NPC by SVM, in which nearly half of them have anticancer effects according to the literature. The 2 top‐ranked drugs, thioridazine and vorinostat, were demonstrated to be effective in inhibiting NPC cells.ConclusionThis in silico approach provides a promising strategy for screening potential therapeutic drugs for NPC treatment. © 2013 Wiley Periodicals, Inc. Head Neck, 36: 1398–1407, 2014
Salivary duct carcinoma with rhabdoid features: Report of 2 cases with immunohistochemical and ultrastructural analyses
Authors: Kusafuka Kimihide , Onitsuka Tetsuro , Muramatsu Koji , Miki Tomoko , Murai Chika , Suda Toshihito , Fuke Tomohito , Kamijo Tomoyuki , Iida Yoshiyuki , Nakajima Takashi 
Published: August 2013

AbstractBackgroundSalivary duct carcinoma with rhabdoid features is extremely rare.MethodsWe report 2 cases of salivary duct carcinoma with rhabdoid features treated at our institution.ResultsCase 1 was a 44‐year‐old Japanese man who had swelling in the left parotid region. This tumor consisted of residual pleomorphic adenoma and widely invasive carcinoma, which showed a diffuse growth pattern by atypical rhabdoid cells. Case 2 was a 66‐year‐old Japanese man who had swelling of the right cervical region. This submandibular tumor was also composed of both residual pleomorphic adenoma region and invasive adenocarcinoma components, whereas some metastatic lesions were purely composed of rhabdoid cells. Such cells were strongly and diffusely positive for cytokeratins (CKs), gross cystic disease fluid protein‐15 (GCDFP), and androgen receptor (AR). Case 1 was also positive for Her‐2 and p53.ConclusionBoth patients were diagnosed with carcinoma ex pleomorphic adenoma and their carcinomatous components were composed of salivary duct carcinoma with rhabdoid features, which is a highly aggressive tumor, similar to salivary duct carcinoma. © 2013 The Authors. Head & Neck published by Wiley Periodicals, Inc. Head Neck 36: E28–E35, 2014
Stomal recurrence: Salvage surgery and reconstruction utilizing microvascular free tissue transfer
Authors: Pittman Amy , Lindau Robert , Andersen Peter , Wax Mark K. 
Published: August 2013

AbstractBackgroundStomal recurrence in patients after laryngectomy has a poor prognosis. Studies performed using sternal resection with pectoralis flap reconstruction report <25% 2‐year survival. The purpose of this study was to ascertain whether the use of larger resection with free flap reconstruction improves survival.MethodsThirteen cases of stomal recurrence that underwent extended sternal resection and free flap reconstruction were identified and classified according to Sisson criteria. Postoperative morbidity, mortality, and survival were assessed.ResultsMedian survival was 10 months in patients with Sisson types I and II, with 37.5% 1‐year and 25% 2‐year survival. Median survival was 6 months in patients with Sisson types III and IV, with 40% 1‐year and 0% 2‐year survival. There were 2 perioperative deaths and a major morbidity rate of 45%.ConclusionSalvage surgery using free flap reconstruction did not show improved survival rates compared with previously described techniques. © 2013 Wiley Periodicals, Inc. Head Neck, 36: 1431–1434, 2014
Utilization of fentanyl buccal tablets in England: Exploring off‐label use reported in a cohort study
Authors: Osborne V. , Layton D. , Fogg C. , Al‐Shukri M. , Shakir S.A.W. 
Published: August 2013

AbstractBackgroundFentanyl citrate buccal tablets are indicated for the treatment of breakthrough pain (BTP) in cancer, in adults who are receiving maintenance opioid therapy for chronic cancer pain.ObjectiveOne of the objectives of this study was to describe the utilization characteristics of patients prescribed fentanyl buccal and to assess how the product is being used in relation to the terms of license of marketing approval.MethodsAn observational post‐marketing cohort study was conducted. For the analysis of this study, exposure data were collected from dispensed prescriptions issued by general practitioners (GPs) between March 2009 and June 2011. Outcome data (indication, event, patient demographic and selected clinical characteristics) were collected by sending questionnaires to GPs at least 6 months after the drug was first prescribed. Summary descriptive statistics were calculated.ResultsThe cohort consisted of 551 patients, of which 54.8% (n = 302 patients) were female. The median age for the cohort was 62 years (interquartile range: 50–72 years), with one patient (0.2%) aged less than 18 years. A primary indication of BTP in cancer was reported for 61.9% (n = 341) patients. Regular opioid therapy was reported upon starting the treatment for 383 patients (69.5% of cohort). In total, 69 patients (12.5%) had one or more contraindications for use. The most frequent initial titration dose was 100 μg/day (n = 247).ConclusionsThe final study results show that fentanyl buccal is largely being prescribed according to the terms of the license in general practice in England, but off‐licence use and use in the presence of contraindications and warnings have been reported.