bluuebunny/crossref_metadata_2025_split huggingface dataset:
Using Transmediation in Elementary Preservice Teacher Education
Authors: Magee Paula A. , Leeth Jane H. 
Published: October 2014

AbstractIn this article, we examine the use of transmediation as a means of reading comprehension across content areas in an elementary teacher education program. The use of transmediation (moving from one sign system to another), coupled with the use of social issue/critical issue texts, supports the idea of connecting with text to develop deeper understandings. A major focus of this study was the collaboration between two courses (reading methods and science methods) with the same group of elementary preservice teachers (interns). The collaboration spanned over six semesters, resulted in over 250 intern artifacts, and supported the use and success of transmediation as a reading experience. Analysis of the artifacts and subsequent findings reveal that given repeated opportunities to engage with critical texts and multiple opportunities to use alternative sign systems to make meaning (transmediation), interns were able to understand and connect to their texts in provocative and meaningful ways.
Tween‐80 and impurity induce anaphylactoid reaction in zebrafish
Authors: Yang Rui , Lao Qiao‐Cong , Yu Hang‐Ping , Zhang Yong , Liu Hong‐Cui , Luan Lin , Sun Hui‐Min , Li Chun‐Qi 
Published: October 2014

AbstractA number of recent reports suspected that Tween‐80 in injectable medicines, including traditional Chinese medicine injections could cause life‐threatening anaphylactoid reaction, but no sound conclusion was drawn. A drug‐induced anaphylactoid reaction is hard to be assayed in vitro and in conventional animal models. In this study, we developed a microplate‐based quantitative in vivo zebrafish assay for assessing anaphylactoid reaction and live whole zebrafish mast cell tryptase activity was quantitatively measured at a wavelength of 405 nm using N‐benzoyl‐dl‐arginine p‐nitroanilide as a substrate. We assessed 10 batches of Tween‐80 solutions from various national and international suppliers and three Tween‐80 impurities (ethylene glycol, 2‐chloroethanol and hydrogen peroxide) in this model and found that three batches of Tween‐80 (nos 2, 20080709 and 20080616) and one Tween‐80 impurity, hydrogen peroxide (H2O2), induced anaphylactoid reactions in zebrafish. Furthermore, we found that H2O2 residue and peroxide value were much higher in Tween‐80 samples 2, 20080709 and 20080616. These findings suggest that H2O2 residue in combination with oxidized fatty acid residues (measured as peroxide value) or more likely the oxidized fatty acid residues in Tween‐80 samples, but not Tween‐80 itself, may induce anaphylactoid reaction. High‐throughput zebrafish tryptase assay developed in this report could be used for assessing safety of Tween‐80‐containing injectable medicines and potentially for screening novel mast cell‐modulating drugs. Copyright © 2014 John Wiley & Sons, Ltd.
Intralesional bevacizumab in patients with Human immunodeficiency virus–associated Kaposi's sarcoma in the upper airway
Authors: Ablanedo‐Terrazas Yuria , Alvarado‐de la Barrera Claudia , Ormsby Christopher E. , Ruiz‐Cruz Matilde , Reyes‐Terán Gustavo 
Published: October 2014

Objectives/HypothesisThe aim of this study was to evaluate the efficacy and safety of intralesional bevacizumab, a monoclonal antibody against vascular endothelial growth factor, in patients with human immunodeficiency virus (HIV)‐associated Kaposi's sarcoma of the upper airway receiving antiretroviral therapy.Study DesignA pilot randomized, open, phase II study.MethodsHIV‐infected patients with Kaposi's sarcoma lesions of the upper airway in the T0 stage were randomized to receive antiretroviral therapy alone or antiretroviral therapy with intralesional bevacizumab. The primary end point was the assessment of changes in tumor size according to the Response Evaluation Criteria In Solid Tumors (RECIST); the secondary end point was safety.ResultsOf the 14 patients with Kaposi's sarcoma included in the study, seven were assigned to the bevacizumab group and seven to the control group. The median age was 30.5 years (interquartile range [IQR], 24.7–38.2). Four patients (28.5%) had >150 CD4 T cells/mm3. Nine patients had lesions in the oral cavity; three patients had pharyngeal disease; one patient had laryngeal involvement; and one patient had oral cavity, pharyngeal, and laryngeal involvement. Four patients had complete response (28.5%), two had partial response, six had stable disease, and two had progressive disease. The median time to complete response was 13 weeks (IQR, 7.5–36.5). No statistical differences between groups were observed (P = .124). In the bevacizumab group, one patient had a grade I adverse event, and another patient had a grade II adverse event.ConclusionsIntralesional administration of bevacizumab was well tolerated but had no impact on upper respiratory tract Kaposi's sarcoma lesions of HIV‐infected patients.Level of Evidence1b Laryngoscope, 125:E132–E137, 2015
Effect of preterm birth on exercise capacity: A systematic review and meta‐analysis
Authors: Edwards Martin O. , Kotecha Sarah J. , Lowe John , Watkins W. John , Henderson A. John , Kotecha Sailesh 
Published: October 2014

SUMMARYBackgroundSurvivors of preterm‐birth have increased prevalence of respiratory, cardiovascular, and neurological diseases in later life however, the overall impact of prematurity on cardiorespiratory exercise capacity is unclear.ObjectiveWe, therefore, systematically reviewed the literature on cardiorespiratory exercise capacity in survivors of preterm birth.MethodologyRelevant studies up to March 2013 were searched using eight electronic health databases. Studies reporting exercise capacity in participants born preterm (<37 weeks) were included. The main outcome of interest was oxygen uptake () at maximal exercise. Data were categorized into four groups: (i) preterm‐born subjects including those with or without bronchopulmonary dysplasia (BPD) but excluding study groups biased towards BPD; (ii) preterm‐born subjects (BPD excluded); (iii) preterm‐born subjects who had BPD28 (defined as oxygen dependency at 28 days of life) in infancy; (iv) preterm born subjects with BPD36 (oxygen dependency at 36 weeks post menstrual age) in infancy.ResultsFrom 9,341 abstracts, 22 included publications reported in ml/kg/min from 685 preterm and 680 term‐born subjects. Overall 20 studies reported results for preterm‐born subjects including BPD; 14 studies for the preterm group excluding BPD; 10 studies for the BPD28 group; and 8 studies for BPD36 group. The mean differences (95% CI) for the four groups were −2.20 (−3.70, −0.70) ml/kg/min; −2.26 (−4.44, −0.07 ml/kg/min; −3.04 (−5.48, −0.61) ml/kg/min, and −3.05 (−5.93, −0.18) ml/kg/min, respectively.ConclusionDespite marked deficits in spirometry, preterm‐born children have a marginally decreased , which is unlikely to be of great clinical significance. Pediatr Pulmonol. 2015; 50:293–301. © 2014 Wiley Periodicals, Inc.
Memoryless variable structure control for affine nonlinear systems using only output information
Authors: Yan Xing‐Gang , Spurgeon Sarah K. , Zhu Quanmin , Zhang Qingling 
Published: October 2014

SummaryIn this paper, local stabilisation is considered for a class of affine nonlinear control systems with uncertainties involving time‐varying delay. It is not assumed that either the dimension of the inputs is equal to the dimension of the outputs or that the nominal system is linearisable or partially linearisable. The bounds on both the matched and mismatched uncertainties are nonlinear and time delayed. A static output feedback variable structure control is synthesized to stabilise the system uniformly asymptotically. A control strategy to enforce exponential stability is also derived. The Lyapunov–Razumikhin approach is used to deal with the effect of the time delay, and the bounds on the uncertainties are used in the control design to enhance the robustness. The designed control does not depend on the time delay, and thus, it is not required that the time delay is known. Finally, the obtained results are tested on a simple mechanical system through simulation. The simulation results show that the proposed approach is effective and feasible. Copyright © 2014 John Wiley & Sons, Ltd.
Clinical utility of third‐trimester uterine artery Doppler in the prediction of brain hemodynamic deterioration and adverse perinatal outcome in small‐for‐gestational‐age fetuses
Authors: Cruz‐Martinez R. , Savchev S. , Cruz‐Lemini M. , Mendez A. , Gratacos E. , Figueras F. 
Published: October 2014

ABSTRACTObjectiveTo assess the clinical value of third‐trimester uterine artery (UtA) Doppler ultrasound in the prediction of hemodynamic deterioration and adverse perinatal outcome in term small‐for‐gestational‐age (SGA) fetuses.MethodsUtA Doppler parameters, cerebroplacental ratio (CPR) and fetal middle cerebral artery (MCA) pulsatility index (PI) were evaluated weekly, starting from the time of SGA diagnosis until 24 h before induction of labor, in a cohort of 327 SGA fetuses with normal umbilical artery PI (< 95th centile), delivered at > 37 weeks' gestation. Differences in the sequence of CPR and MCA‐PI changes < 5th centile, between the group with normal UtA Doppler indices at diagnosis and those with abnormal UtA indices, were analyzed by survival analysis. In addition, the use of UtA Doppler value, alone or in combination with a brain Doppler scan before delivery, to predict the risk of Cesarean section, Cesarean section for non‐reassuring fetal status (NRFS), neonatal acidosis and neonatal hospitalization was evaluated by logistic regression analysis, adjusted for gestational age at birth and birth‐weight percentile.ResultsAbnormal UtA Doppler at diagnosis of SGA was associated with a higher risk of developing abnormal brain Doppler indices before induction of labor than in those with a normal UtA at diagnosis (62.7% vs 34.6%, respectively; P < 0.01). Compared to those with normal UtA Doppler indices, those with abnormal UtA Doppler findings were associated with a higher risk of intrapartum Cesarean section (52.2% vs 37.3%, respectively; P = 0.03), Cesarean section for NRFS (35.8% vs 23.1%, respectively; P = 0.03), neonatal acidosis (10.4% vs 7.7%, respectively; P = 0.47) and neonatal hospitalization (23.9% vs 16.5%, respectively; P = 0.16). Logistic regression analysis indicated that UtA Doppler findings were not significantly associated with adverse perinatal outcome independent of brain Doppler findings.ConclusionUtA Doppler indices predict adverse perinatal outcome, but do not help to improve the predictive value of brain Doppler indices. However, at the time of SGA diagnosis they identify the subgroup of fetuses at highest risk of progression to abnormal brain Doppler findings. Copyright © 2014 ISUOG. Published by John Wiley & Sons Ltd.
An overview of pre‐ribosomal RNA processing in eukaryotes
Authors: Henras Anthony K. , Plisson‐Chastang Célia , O'Donohue Marie‐Françoise , Chakraborty Anirban , Gleizes Pierre‐Emmanuel 
Published: October 2014

Ribosomal RNAs are the most abundant and universal noncoding RNAs in living organisms. In eukaryotes, three of the four ribosomal RNAs forming the 40S and 60S subunits are borne by a long polycistronic pre‐ribosomal RNA. A complex sequence of processing steps is required to gradually release the mature RNAs from this precursor, concomitant with the assembly of the 79 ribosomal proteins. A large set of trans‐acting factors chaperone this process, including small nucleolar ribonucleoparticles. While yeast has been the gold standard for studying the molecular basis of this process, recent technical advances have allowed to further define the mechanisms of ribosome biogenesis in animals and plants. This renewed interest for a long‐lasting question has been fueled by the association of several genetic diseases with mutations in genes encoding both ribosomal proteins and ribosome biogenesis factors, and by the perspective of new anticancer treatments targeting the mechanisms of ribosome synthesis. A consensus scheme of pre‐ribosomal RNA maturation is emerging from studies in various kinds of eukaryotic organisms. However, major differences between mammalian and yeast pre‐ribosomal RNA processing have recently come to light. WIREs RNA 2015, 6:225–242. doi: 10.1002/wrna.1269This article is categorized under:

RNA Interactions with Proteins and Other Molecules > RNA–Protein Complexes
RNA Processing > rRNA Processing
RNA in Disease and Development > RNA in Disease
Theoretical and Experimental Analysis of Structural Phase Transitions for ScF[SeO3] and YF[SeO3]
Authors: Chou Sheng‐Chun , Greiner Stefan , Magdysyuk Oxana V. , Dinnebier Robert E. , Schleid Thomas 
Published: October 2014

AbstractPhase‐pure ScF[SeO3] and YF[SeO3] were synthesized via solid‐state reactions of the corresponding rare‐earth metal sesquioxides and trifluorides with selenium dioxide in excess of fluxing cesium bromide at 700 °C for 7 d. To avoid the formation of oxosilicates, these reactions took place in corundum crucibles embedded inside of evacuated fused silica ampoules. Upon cooling down below 13 °C, a pseudo‐second‐order phase transition (P21/m → P$\bar{1}$ or P1) for ScF[SeO3] occurs, which is similar to the high‐temperature phase transition of LuF[SeO3]. By heating YF[SeO3] above 319 °C, it undergoes a first‐order phase transition (P21/c → P21/m) without passing the intermediate P$\bar{1}$ modification in contrast to LuF[SeO3]. Both the high‐temperature phase transition of YF[SeO3] and the low‐temperature phase transition of ScF[SeO3] were characterized by in‐situ X‐ray powder diffraction, X‐ray single‐crystal diffraction, thermal analysis DSC, and distortion‐mode analysis. For both cases the driving forces for the symmetry‐breaking phase transitions from the high‐ to the low‐temperature phases are discussed.
A Comparison of Video Laryngoscopy to Direct Laryngoscopy for the Emergency Intubation of Trauma Patients
Authors: Michailidou Maria , O’Keeffe Terence , Mosier Jarrod M. , Friese Randall S. , Joseph Bellal , Rhee Peter , Sakles John C. 
Published: October 2014

AbstractBackgroundDirect laryngoscopy (DL) has long been the gold standard for tracheal intubation in emergency and trauma patients. Video laryngoscopy (VL) is increasingly used in many settings and the purpose of this study was to compare its effectiveness to direct laryngoscopy in trauma patients. Our hypothesis was that the success rate of VL would be higher than that of DL.MethodsData were collected prospectively on all trauma patients, from January 2008 to June 2011, who were intubated emergently in an academic level I trauma center. After intubation, the physician that performed the intubation completed a structured data collection form that included demographics, complications, and the presence of difficult airway predictors. Our primary outcome measure was overall successful tracheal intubation, which was defined as successful intubation with the first device used.ResultsDuring the study period, 709 trauma patients were intubated by either VL or DL. VL was performed in 55 % of cases. The overall success rate of VL was 88 % compared to 83 % with DL (P = 0.05). Cervical (C‐Spine) immobilization was predictive of higher initial success with VL (87 %) than with DL (80 %) (P < 0.05). In multivariate regression analysis DL was associated with higher risk of intubation failure compared to VL (OR 1.82, CI: 1.15–2.86).ConclusionsIn trauma patients intubated emergently, VL had a significantly higher success rate than DL. These data suggest that, in select circumstances, VL is superior to DL for the intubation of trauma patients with difficult airways.
Uniqueness of gradient Gibbs measures with disorder
Authors: Cotar Codina , Külske Christof 
Published: October 2014

AbstractWe consider—in a uniformly strictly convex potential regime—two versions of random gradient models with disorder. In model (A) the interface feels a bulk term of random fields while in model (B) the disorder enters through the potential acting on the gradients. We assume a general distribution on the disorder with uniformly-bounded finite second moments. It is well known that for gradient models without disorder there are no Gibbs measures in infinite volume in dimension $$d = 2$$

d
=
2

, while there are shift-invariant gradient Gibbs measures describing an infinite-volume distribution for the gradients of the field, as was shown by Funaki and Spohn (Commun Math Phys 185:1–36, 1997). Van Enter and Külske proved in (Ann Appl Probab 18(1):109–119, 2008) that adding a disorder term as in model (A) prohibits the existence of such gradient Gibbs measures for general interaction potentials in $$d = 2$$

d
=
2

. In Cotar and Külske (Ann Appl Probab 22(5):1650–1692, 2012) we proved the existence of shift-covariant random gradient Gibbs measures for model (A) when $$d\ge 3$$

d
≥
3

, the disorder is i.i.d and has mean zero, and for model (B) when $$d\ge 1$$

d
≥
1

and the disorder has a stationary distribution. In the present paper, we prove existence and uniqueness of shift-covariant random gradient Gibbs measures with a given expected tilt$$u\in {\mathbb R}^{d}$$

u
∈

R

d

and with the corresponding annealed measure being ergodic: for model (A) when $$d\ge 3$$

d
≥
3

and the disordered random fields are i.i.d. and symmetrically-distributed, and for model (B) when $$d\ge 1$$

d
≥
1

and for any stationary disorder-dependence structure. We also compute for both models for any gradient Gibbs measure constructed as in Cotar and Külske (Ann Appl Probab 22(5):1650–1692, 2012), when the disorder is i.i.d. and its distribution satisfies a Poincaré inequality assumption, the optimal decay of covariances with respect to the averaged-over-the-disorder gradient Gibbs measure.
Tsunami impact on the population development of a critically endangered hummingbird species of a Pacific island
Authors: Hahn Ingo , Vergara Pablo M. , Baumeister Julia , Soto Gerardo E. , Römer Uwe 
Published: October 2014

AbstractIt is a long‐standing question how tsunamis can influence wild populations of animals and plants. Here, we assessed short‐term changes in the population of the critically endangered Juan Fernández Firecrown (Sephanoides fernandensis) by using abundance data recorded 1 year before and 1 year after the 2010 Chilean tsunami. We tested that the abundance of Firecrowns declined in the areas where the tsunami caused the massive loss of Cabbage Trees, an important seasonal nectar source for Firecrowns. The abundance of Juan Fernández Firecrowns decreased after the tsunami, but also was affected by the habitat type, altitude, and the abundance of Cabbage Trees. Firecrowns tended to be more abundant in settlement areas than in native forest whereas the reduction in Firecrown abundance after the tsunami was more intense in settlement areas than in native forest. As expected, this habitat effect was dependent on the massive loss of Cabbage Trees in settlement areas following the tsunami. In spite of the short‐term nature of our data, our results are conclusive in showing that the loss of an important food source causes short‐term changes in the distribution and abundance of Firecrowns, which, in turn, could contribute to population decline.
Genetic Counseling for Indigenous Australians: an Exploratory Study from the Perspective of Genetic Health Professionals
Authors: Kowal Emma , Gallacher Lyndon , Macciocca Ivan , Sahhar Margaret 
Published: October 2014

AbstractIndigenous populations are thought to have particularly low levels of access to genetic health services, and cultural issues may be a contributing factor. This article presents the findings of the first study of genetic health service provision to Indigenous Australians. This qualitative study aimed to identify elements of culturally‐competent genetic health service provision in Indigenous Australian contexts. Twelve semi‐structured interviews were conducted with genetic counselors and clinical geneticists from around Australia who had delivered services to Indigenous Australians. Participants were asked to describe their experiences and identify any collective cultural needs of Indigenous clients, as well as comment on specific training and resources they had received or used. Interviews were audio‐recorded and transcribed with thematic analysis conducted on the data. The findings show that participants were reluctant to generalize the needs of Indigenous peoples. Some participants asserted that Indigenous peoples have needs that differ from the general population, while others felt that there were no collective cultural needs, instead advocating an individualized approach. Being flexible and practical, taking time to build rapport, recognizing different family structures and decision‐making processes, as well as socio‐economic disadvantage were all identified as important factors in participants’ interactions with Indigenous clients. Indigenous support workers and hospital liaison officers were seen as valuable resources for effective service provision. The implications of this study for training and practice are discussed.
Supply network disruption and resilience: A network structural perspective
Authors: Kim Yusoon , Chen Yi‐Su , Linderman Kevin 
Published: October 2014

AbstractIncreasingly, scholars recognize the importance of understandingsupply network disruptions. However, the literature still lacks a clear conceptualization of a network‐level understanding of supply disruptions. Not having a network level understanding of supply disruptions prevents firms from fully mitigating the negative effects of a supply disruption. Graph theory helps to conceptualize a supply network and differentiate between disruptions at the node/arc level vs. network level. The structure of a supply network consists of a collection of nodes (facilities) and the connecting arcs (transportation). From this perspective, small events that disrupt a node or arc in the network can have major consequences for the network. A failure in a node or arc can potentially stop the flow of material across network. This study conceptualizes supply network disruption and resilience by examining the structural relationships among entities in the network. We compare four fundamental supply network structures to help understand supply network disruption and resilience. The analysis shows that node/arc‐level disruptions do not necessarily lead to network‐level disruptions, and demonstrates the importance of differentiating a node/arc disruption vs. a network disruption. The results also indicate that network structure significantly determines the likelihood of disruption. In general, different structural relationships among network entities have different levels of resilience. More specifically, resilience improves when the structural relationships in a network follow thepower‐law. This paper not only offers a new perspective of supply network disruption, but also suggests a useful analytical approach to assessing supply network structures for resilience.