bluuebunny/crossref_metadata_2025_split huggingface dataset:
Drivers of associations between daytime-nighttime compound temperature extremes and mortality in China
Authors: Yang Jun , Zhou Maigeng , Guo Cui , Zhu Sui , Sakhvidi Mohammad Javad Zare , Requia Weeberb J. , Sun Qinghua , Tong Shilu , Li Mengmeng , Liu Qiyong 
Published: June 2024

Abstract
Background
Temperature extremes are anticipated to become more frequent and more intense under the context of climate change. While current evidence on health effects of compound extreme temperature event is scarce.

Methods
This nationwide cross-sectional study collected daily data on weather and mortality for 161 Chinese districts/counties during 2007-2013. A quasi-Poisson generalized linear model was first applied to assess effects of daytime-only, nighttime-only and compound daytime-nighttime heat wave (and cold spell) on cause-specific mortality. Then a random-effect meta-analysis was used to produce pooled estimates at national level. Stratification analyses were performed by relative humidity, individual and regional characteristics.

Results
Here we show that mortality risks of compound daytime-nighttime temperature extremes are much higher than those occurring only in the daytime or nighttime. Humid weather further exaggerates the mortality risk during heat waves, while dry air enhances the risk during cold weather. People who are elderly, illiterate, and those with ischemic heart disease and respiratory disease are particularly vulnerable to extreme temperature. At the community-level, population size, urbanization rate, proportion of elderly and PM2.5 are positively associated with increased risks associated with heat waves. Temperature, humidity and normalized difference vegetation index are positively associated with the effects of cold weather, with an opposite trend for latitude and diurnal temperature range.

Conclusions
This nationwide study highlights the importance of incorporating compound daytime-nighttime extreme temperature events and humid conditions into early warning systems and urban design/planning.
Advancing cancer detection with portable salivary sialic acid testing
Authors: Elgendi Mohamed , Lyzwinski Lynnette , Kübler Eric , Shokurov Alexander V. , Howard Newton , Menon Carlo 
Published: June 2024

AbstractThis perspective emphasizes the robust evidence supporting salivary sialic acid (SA) as a valuable tool for cancer prescreening, particularly for oral and breast cancers. The potential benefits of salivary SA testing include early cancer detection and treatment response monitoring. The challenges and opportunities of developing a portable cancer detection device are discussed. Enabling accessible and timely prescreening through salivary SA testing has the potential to save lives and offer an alternative to mammograms for low-risk groups. Portable Raman spectrometers show promise for SA analysis, but cost and sensitivity challenges need attention. The potential for personalized medicine, multiplexing capabilities, and remote collaboration further enhances the value of portable Raman-based cancer detection devices. Implementing these recommendations may lead to the future use of portable devices in cancer detection through salivary SA analysis. Salivary SA’s promising potential as a prescreening or adjunct biomarker extends beyond the clinical setting, and its integration into routine practice could empower individuals for home-based cancer detection, enabling more convenient and effective health monitoring.
Facile, green and scalable synthesis of single-layer manganese dioxide nanosheets and its application for GSH and cTnI colorimetric detection
Authors: Xiao Yao , Peng TaoMei , Luo YuXiao , Jiao Lei , Huang TaiXing , Li He 
Published: June 2024

A facile, green method and scalable synthesis of MnO2 nanosheets by mixing Shiranui mandarin orange juice and KMnO4. A rapid and robust colorimetric assay was developed for the quantification of GSH and cTnI based on MnO2 nanosheets-TMB system.
A novel stochastic framework for optimal scheduling of smart cities as an energy hub
Authors: Shokri Masoud , Niknam Taher , Mohammadi Mojtaba , Dehghani Moslem , Siano Pierluigi , Ouahada Khmaies , Sarvarizade‐Kouhpaye Miad 
Published: June 2024

AbstractSmart cities consist of various energy systems and services that must be optimally scheduled to improve energy efficiency and reduce operation costs. The smart city layout comprises a power distribution system, a thermal energy system, a water system, and the private and public transportation systems. Additionally, several new technologies such as reconfiguration, regenerative braking energy of the metro, etc. are considered. This study is one of the first to consider all these technologies together in a smart city. The proposed power distribution system is a grid‐connected hybrid AC–DC microgrid. The biogeography‐based optimization algorithm was utilized to seek the best solution for scheduling micro‐turbines, fuel cells, heat pumps, desalination units, energy storage systems, AC–DC converters, purchasing power from the upstream, distributed energy resources, and transferring power amongst electric vehicle parking stations and metro for the next day. Also, the reduced unscented transformation layout was used to capture the system's uncertainty. The suggested layout is implemented on an enhanced IEEE 33‐bus test system to show the efficiency of the suggested method. The results show that costs and environmental pollution are reduced. By comparing the proposed smart city with other studies, the efficiency and completeness of the proposed smart city are shown.
Iris image retrieval using partial matching of image blocks
Authors: Afkhamnia Fahimeh , Boroujeni Farsad Zamani , Soltanaghaei Mohammad Reza 
Published: June 2024

AbstractThe problem of human identification through recognition of patterns in iris images captured in unconstrained environments results in image artefacts such as image occlusion and specular reflection, in which iris tissue is observable to extremely low content. To overcome this problem, this paper presents a novel method for iris image retrieval and recognition based on partial pattern matching. The main contribution of the proposed method relies on an image partitioning schema in which the iris is divided into non‐overlapping blocks with varying dimensions, facilitating the identification and removal of image regions impaired by eyelids, eyelashes, and specular reflections. In fact, the blocks that contain artefacts are completely ignored and those blocks are preserved that include useful patterns for identification. In addition, a multi‐feature similarity followed by a score fusion technique is employed for ranking the retrieval results. The remarkable results of the classification stage include an accuracy of 100%, 98.75%, and 99.94% on three benchmark databases, including UPOL, UBIRIS.V2, and CASIA‐Iris‐Interval.v3, respectively. Additionally, in the retrieval stage, the proposed method achieves a precision of 100% on all three benchmark databases, a recall of 83.33%, and a F1‐measure of 90.91 on the CASIA‐Iris‐Interval.v3 dataset.
The imprint of magnetic fields on absorption spectra from circumgalactic wind-cloud systems
Authors: Casavecchia Benedetta , Banda-Barragán Wladimir E. , Brüggen Marcus , Brighenti Fabrizio , Scannapieco Evan 
Published: June 2024

Context. Galactic winds determine how stellar feedback regulates the mass and metallicity of galaxies. Observational studies show that galactic winds are multi-phase and magnetised. In the local Universe, the dense phase is traced by emission and absorption lines, which reveal the presence of fast-moving clouds embedded in hot streams. Simulations of such streams indicate to us that magnetic fields can shield such clouds and help to delay their disruption, but observational effects are rarely discussed.
Aims. Using a suite of 3D magnetohydrodynamical simulations, we studied the influence of two orientations of the magnetic field (aligned and transverse to the wind) on the cloud morphology, temperature and density structure, mixing fraction, ion kinematics, column densities, and absorption spectra.
Methods. We numerically studied supersonic wind-cloud systems with radiative processes, and developed a framework to extract ion column density maps and synthetic absorption spectra. The framework relies on studying ion populations and creating down-the-barrel spectra via an interface that links our PLUTO simulations to TRIDENT using the yt-package infrastructure, CLOUDY, and STARBURST99.
Results. We find that the transverse initial magnetic field makes the cloud asymmetric, shields and protects dense cold gas, and reduces mixing fractions compared to the aligned case. Ions can reach higher velocities in the transverse field case. The imprints of the initial orientation of the field on the synthetic spectra can be described as follow: (a) in the cold phase, we find no signature of C II and Si II when the field is aligned; (b) in the intermediate phase traced by C IV and Si IV, we find broader lines in the transverse case; and (c) in the warm phase, we find deeper lines for O VI and N V in the aligned case, but they are less sensitive overall to the field orientation.
Conclusions. Magnetic fields significantly affect the absorption spectra of cold clouds. Intermediate ions are the most sensitive to the magnetic field orientation and can potentially yield information about magnetic field topology.
Ultra-low-frequency LOFAR spectral indices of cluster radio halos
Authors: Pasini T. , De Gasperin F. , Brüggen M. , Cassano R. , Botteon A. , Brunetti G. , Edler H. W. , van Weeren R. J. , Cuciti V. , Shimwell T. , Di Gennaro G. , Gaspari M. , Hardcastle M. , Rottgering H. J. A. , Tasse C. 
Published: June 2024

Context. A fraction of galaxy clusters harbor diffuse radio sources known as radio halos. The prevailing theory regarding their formation is based on second-order Fermi reacceleration of seed electrons caused by merger-driven turbulence in the intra-cluster medium. This mechanism is expected to be inefficient, which implies that a significant fraction of halos should have very steep energy spectra (α < −1.5).
Aims. We start investigating the potential and current limitations of the combination of the two surveys conducted by LOFAR, LoTSS (144 MHz) and LoLSS (54 MHz), to probe the origin of radio halos.
Methods. We followed up the 20 radio halos detected in Data Release 1 of LoTSS, which covers the HETDEX field, with the LoLSS survey, and we studied their spectral properties between 54 and 144 MHz.
Results. After removing compact sources, nine halos were excluded due to unreliable halo flux density measurements at 54 MHz. Our main finding is that 7 out of 11 (∼64%) exhibit an ultra-steep spectrum (α < −1.5), which is a key prediction of turbulent reacceleration models. We also note a tentative trend for more massive systems to host flatter halos, although the currently poor statistics do not allow for a deeper analysis.
Conclusions. Our sample suffers from low angular resolution at 54 MHz, which limits the accuracy of the compact-source subtraction. Nevertheless, this study is the first step toward providing compelling evidence for the existence of a large fraction of radio halos with a very steep spectrum, which is a fundamental prediction of turbulent reacceleration models. In this regard, the forthcoming second data release of LoLSS, along with the integration of LOFAR international stations and the instrumental upgrade to LOFAR2.0, will improve both the statistics and the low-frequency angular resolution, allowing us to determine the origin of radio halos in galaxy clusters conclusively.
Comment faciliter l’intégration de patients partenaires dans les programmes d’ETP ? Étude qualitative
Authors: Mignot Mélanie , Frazier-Mironer Aline , Gruit Violette 
Published: June 2024

Introduction : L’intégration de patients partenaires (PP) est une opportunité d’amélioration pour les programmes d’éducation thérapeutique du patient (ETP), mais représente un véritable enjeu pour les professionnels de santé. Objectif : Observer et comprendre les facteurs qui limitent ou favorisent l’intégration de PP au sein des programmes d’ETP du point de vue des professionnels de santé. Méthodes : Dans cette étude qualitative, des entretiens semi-dirigés ont été réalisés auprès de treize professionnels de santé, puis analysés selon la théorie ancrée. Résultats : Les freins à l’intégration de PP au sein de programmes d’ETP sont le manque de connaissances sur le partenariat patient, les difficultés pratiques à sa mise en œuvre, et diverses peurs et croyances sur le déroulement d’un tel partenariat. Toutefois, les personnes interrogées reconnaissent les bénéfices de l’intégration d’un PP, proposent une meilleure définition du cadre d’intégration et soulignent l’importance de la communication en équipe pour un partenariat réussi. Les expériences passées avec des PP influencent positivement le ressenti face au partenariat. Discussion et conclusion : Les professionnels de santé impliqués en ETP sont conscients de l’importance de l’intégration de PP mais ont besoin d’un accompagnement hiérarchique et institutionnel pour la mener à bien. Les structures ressources telle que les Unités Transversale d’ETP (UTEP) peuvent jouer un rôle pour faciliter cette démarche.
Kontinuierliche Glukosemessung bei Menschen mit Typ-2-Diabetes ohne intensivierte Insulintherapie: eine Standortbestimmung
Authors: Seufert Jochen , Dänschel Ingrid , Gölz Stefan , Haller Nicola , Kulzer Bernhard , Tan Susanne , Schnell Oliver , Wiesner Tobias , Kroeger Jens 
Published: June 2024

ZusammenfassungZahlreiche Studien haben den klinischen Nutzen der kontinuierlichen Glukosemessung (CGM) bei Menschen mit Typ-1-Diabetes belegt, was auch zu einer positiven Empfehlung des Gemeinsamen Bundesausschusses (GBA) für CGM-Systeme bei Menschen mit Diabetes und intensivierter Insulintherapie (ICT/Insulinpumpentherapie) geführt hat. Inzwischen liegen die Ergebnisse zahlreicher randomisierter, beobachtender und retrospektiver Studien zum Einsatz von CGM bei Menschen mit Typ-2-Diabetes und einer nicht intensivierten Insulintherapie (BOT/SIT/CT) oder einer Therapie ohne Insulin vor. In diesem Artikel wird die aktuelle Evidenz zum Einsatz von CGM bei diesen Patientengruppen zusammengefasst und diskutiert. Die Ergebnisse dieser Studien deuten darauf hin, dass CGM auch bei Menschen ohne intensivierte Insulintherapie wirksam ist, um die glykämische Kontrolle zu verbessern und mögliche Nebenwirkungen der Insulintherapie (Hypoglykämien) zu vermeiden.
Magnesium-Mediated Regioselective Additions of Bromoform to Quinone Methides and Aurone-Derived Azadienes
Authors: Namboothiri Irishi N. N. , Kumar Deepak , Satam Nishikant 
Published: June 2024

AbstractThe magnesium-mediated addition of bromoform to conjugated electron-deficient alkenes and imines, such as para-quinone methides (p-QMs) and aurone-derived azadienes, respectively, is reported here for the first time. While p-QMs undergo exclusive and hitherto unreported 1,6-addition of bromoform to afford benzylic tribromomethylated diarylmethanes, aurone-derived azadienes undergo both 1,2- and 1,4-additions to furnish α- and γ-tribromomethylamines. A mechanism involving the intermediacy of the tribromomethyl radical has been proposed based on control experiments and EPR studies. Representative synthetic transformations have also been carried out.
Prophylactic Venous Supercharging in Deep Inferior Epigastric Artery Perforator Flap Surgery: A Retrospective Dual-Center Study
Authors: Lombardo Giuseppe A.G. , Cherubino Mario , Marchica Paolo , Violini Hillary , Marrella Domenico , Ciancio Francesco , Musmarra Isidoro , Ranno Rosario , Melita Dario 
Published: June 2024

Abstract
Background Deep inferior epigastric artery perforator (DIEP) flap is nowadays considered the gold standard in breast reconstruction. However, venous congestion is still a leading cause of free flap failure. Despite the conspicuous articles regarding the use of a secondary venous anastomosis, there is a lack in the literature regarding the prophylactic use of a secondary venous route to reduce the incidence of complications during breast reconstruction.
Methods A double-center retrospective study based on women undergoing DIEP breast reconstruction was conducted, dividing patients into case group (DIEP flaps with double venous anastomosis) and control group (DIEP flaps with single venous anastomosis). Demographic and surgical data and complications were compared and statistically analyzed, and a reconstructive algorithm was proposed to improve the flap insetting.
Results In total, 154 patients were included in the study, divided into case group (74 patients) and control group (80 patients). The median age at the time of surgery was 49.09 years (range: 29–68 years), slightly lower in group 1 when compared with group 2. The mean body mass index (BMI) was 25.52 kg/m2 (range: 21.09–29.37 kg/m2), in particular 25.47 kg/m2 (range: 23.44–28.63 kg/m2) in group 1 and 25.58 kg/m2 (range: 21.09–29.37 kg/m2) in group 2. No statistical differences were found between groups in terms of BMI and smoking and comorbidities history. The average operative times were 272.16 minutes (range: 221–328 minutes) in group 1 and 272.34 minutes (range: 221–327 minutes) in group 2, with no significant difference between groups, as well as ischemia time (44.4 minutes in group 1 [range: 38–56 minutes] and 49.12 minutes in group 2 [range: 41–67 minutes]). Statistical analysis showed a reduction in short-term complications and a statistically significant reduction for take-backs in the two groups.
Conclusions Our study suggests that venous supercharging of DIEP flap by performing dual venous anastomosis can be routinely and safely done prophylactically, and thus not only after intraoperative assessment of venous congestion, to avoid flap venous congestion and decrease the rates of re-exploration.
The “Flapbot”: A Global Perspective on the Validity and Usability of a Flap Monitoring Chatbot
Authors: Ejaz Hamza , Ali Stephen R. , Berner Juan E. , Dobbs Thomas D. , Whitaker Iain S. ,   Flapbot Collaborative
Published: June 2024

Abstract
Background The Flapbot chatbot assists in free-flap monitoring, emphasizing accessibility, user-friendliness, and global reliability. This study assesses Flapbot's worldwide validity and usability and uses qualitative analysis to identify areas for future enhancement.
Methods Flapbot, built on Google's DialogFlow, was evaluated by international plastic surgeons. Invitations were sent to the International Lower Limb Reconstruction Collaborative (INTELLECT), International Confederation of Plastic Surgery Societies (ICOPLAST), and the International Microsurgery Club. Out of the 42 surgeons who agreed to participate, 21 tested the Flapbot and completed an online survey on its validity and usability. The survey had 13 validity items and 10 usability items. Data analysis involved computing the individual content validity index (I-CVI) and scale-wide content validity index (S-CVI) for validity, and the system usability score (SUS) for usability. Thematic analysis distilled free-text responses to identify key themes.
Results Nine of 13 items had an I-CVI over 0.78, denoting significant relevance. The S-CVI score stood at 0.82, indicating high relevance. The SUS score was 68, representing average usability. Themes highlighted issues with the current model, development suggestions, and surgeons' concerns regarding growing reliance on digital tools in health care.
Conclusion Flapbot is a promising digital aid for free-flap monitoring. While it showcases notable validity and usability, improvements in functionality, usability, and accessibility are needed for broader global use.
Emicizumab in Type 3 von Willebrand Disease: Report of a Case with an Alloantibody and Literature Review
Authors: Giuffrida Anna C. , Siboni Simona M. , Baronciani Luciano , Poli Giovanni , Gandini Giorgio , Peyvandi Flora 
Published: June 2024

AbstractType 3 von Willebrand disease (VWD), the most severe form of VWD, is an inherited recessive bleeding disorder caused by the complete deficiency of von Willebrand factor (VWF). The reported prevalence is 1 per million but varies worldwide according to the frequency of consanguineous marriages. The clinical phenotype is characterized not only by mucocutaneous bleedings, but also by hemarthroses and muscle hematoma, as in patients with moderate hemophilia. Long-term prophylaxis with factor (F)VIII/VWF concentrates is recommended in patients with a history of severe and frequent bleeds. A rare complication of replacement therapy is the development of alloantibodies against VWF, with the consequences of an ineffective therapy and risk of anaphylactic reactions upon treatment. Emicizumab is the first bispecific monoclonal antibody that mimics FVIII coagulant activity and is approved for prophylaxis of bleeding in patients with inherited hemophilia A with or without inhibitors and recently also for acquired hemophilia. In this manuscript we report and discuss available data in the literature on the use of emicizumab in type 3 VWD and describe the case of a female patient with type 3 VWD with a history of alloantibodies against VWF and posttransfusion anaphylaxis, recently and successfully put on off-label prophylaxis with emicizumab.
Euroscepticism: a meta-analysis
Authors: Marzi Paolo 
Published: June 2024

AbstractThe rise of Euroscepticism has prompted extensive academic investigation, with researchers exploring a wide variety of areas and uncovering substantial information in recent decades. Despite these achievements, the overall self-knowledge of the literature—its overarching themes, the countries scrutinised, the methodologies employed, and their evolution over time—remains relatively underexplored. To bridge this gap, this study utilises wizdom.ai to delineate the borders of Euroscepticism by conducting a meta-analysis of over 400 journal articles between 1995 and 2020. The findings reveal two distinct macro-periods. The first—1995 to 2010—primarily comprises party-based, single-country qualitative studies. Conversely, the latter period—2011 to 2020—witnessed a proliferation of research, marked by an expansion into previously under-investigated topics, countries, and methodologies. This is exemplified by a notable increase in quantitative and comparative publications across many EU Member States. These findings constitute a preliminary basis for assessing the existing breadth and depth of the study of Euroscepticism and may stimulate further research on the topic.
Spatial variability of soil carbon across a hillslope restoration planting in New Zealand
Authors: D’Ath Molly Katharine , Sila-Nowicka Katarzyna , Schwendenmann Luitgard 
Published: June 2024

Context Forest restoration has been adopted by governments and local communities across the globe to restore ecological functions and as a measure to mitigate climate change. Aims This study investigated the spatial variation in landscape, vegetation, soil characteristics, and soil carbon storage under young restoration plantings across a hillslope in northern New Zealand. Methods Soil samples (0–10 cm, 10–20 cm, and 20–30 cm) were taken from 121 locations across 5–20-year-old restoration plantings, remnant and regenerating bush and pasture. Samples were analysed for bulk density, pH, and soil carbon concentration and soil carbon stocks were calculated. Ordinary kriging and multiscale geographically weighted regression (MGWR) were used to predict and explain soil carbon stocks across the landscape. Key results Soil carbon stocks (0–10 cm depth) across the study area ranged from 1.9 to 7.1 kg m−2. Spatial analysis revealed that elevation, slope, stem density, bulk density, and pH had a significant effect on the magnitude and distribution of soil carbon stocks. Conclusions and implications This study has shown that topography had a strong effect on soil carbon stocks across the young restoration plantings. The outcome of this study highlights the importance of taking landscape and soil characteristics into account when planning a forest restoration project.