bluuebunny/crossref_metadata_2025_split huggingface dataset:
An ecocritical reading of flowers in Alice Walker’s The Color Purple
Authors: Arıkan Arda 
Published: July 2015

<p>Flowers are one of the most popular motifs in verse as well as in prose. Many critics have noted that nature is at the core of Alice Walker’s epistolary novel <em>The Color Purple</em> (1983) in which depicting or writing about flowers requires special attention. However, in Alice Walker’s <em>The Color Purple</em>, flowers are depicted and written about to convey strong negative emotions as well as positive ones. In this study, how flowers are depicted or written about in the novel is studied through an ecocritical lens. I argue that Walker’s use of flowers provides examples of the vitality of a hopeful existence especially when various flowers mentioned in the novel are considered along with the seasonal changes organically affecting such floral richness. I equally argue that Walker uses flowers to show the change experienced by the major character, Celie. In that sense, Walker’s flowers are in direct coexistence with the major character, Celie. </p>
Compressible Navier–Stokes limit of binary mixture of gas particles
Authors: Choe Hi Jun , Zhou Shulin 
Published: July 2015

Abstract
In this paper we study the compressible Navier–Stokes limit of binary mixture of gas particles in which a species is dense and the other is sparse.
Their collisions are decided by Grad's hard potentials.
When the Knudsen number of dense species of the Boltzmann system goes to zero, we show that
the hydrodynamic variables satisfy compressible Navier–Stokes type equations.
It turns out that the macro fluid variables corresponding to the dense species satisfy the standard compressible Navier–Stokes equations. But the fluid equations for sparse species contain influence terms of dense species. Like single species gas, we employed Enskog–Chapman and moment methods up to the first order.
Rapid detection of Mmalton α1-antitrypsin deficiency allele by real-time PCR and melting curves in whole blood, serum and dried blood spot samples
Authors: Belmonte Irene , Montoto Luciana , Miravitlles Marc , Barrecheguren Miriam , Esquinas Cristina , Rodríguez Esther , Giralt Marina , Rodríguez-Frías Francisco 
Published: July 2015

AbstractαWe tested the applicability of this new technique for the identification of the Mmalton allele in AATD screening using whole blood, dried blood spot (DBS) and serum samples. Mmalton heterozygote and homozygote samples and samples without this allele were included in the study.This new assay is able to detect homozygous and heterozygous genotypes in the same reaction and in a single step, giving matching results with those obtained byThis technology is optimal for working with small amounts of DNA, such as in DBS and even with residual DNA present in serum samples, allowing improvement in routine algorithms of AATD diagnosis or large-scale screening. This method will be useful for obtaining more in depth knowledge of the real incidence of the Mmalton variant.
Quasiconvexity in relatively hyperbolic groups
Authors: Gerasimov Victor , Potyagailo Leonid 
Published: July 2015

Abstract

We study different notions of quasiconvexity for a subgroup H of
a relatively hyperbolic group G. Our first result implies that relative geometric quasiconvexity is
equivalent to dynamical quasiconvexity as it was conjectured by D. Osin.
In the second part of the paper we prove that a subgroup H of a
finitely generated relatively hyperbolic group G acts
cocompactly outside its limit set if and only if it is
(absolutely) quasiconvex and every infinite intersection of H with
a parabolic subgroup of G has finite index in the parabolic subgroup.
We also discuss relations between other properties of subgroups close to quasiconvexity.
When fat becomes an ally of the enemy: adipose tissue as collaborator in human breast cancer
Authors: Lapeire Lore , Denys Hannelore , Cocquyt Véronique , De Wever Olivier 
Published: July 2015

Abstract
Since the discovery of leptin in 1994, our vision of adipose tissue as a static organ regulating mainly lipid storage and release has been completely overthrown, and adipose tissue is now seen as an active and integral organ in human physiology. In the past years, extensive research has tremendously given us more insights in the mechanisms and pathways involved not only in normal but also in ‘sick’ adipose tissue, for example, in obesity and lipodystrophy. With growing evidence of a link between obesity and several types of cancer, research focusing on the interaction between adipose tissue and cancer has begun to unravel the interesting but complex multi-lateral communication between the different players. With breast cancer as one of the first cancer types where a positive correlation between obesity and breast cancer incidence and prognosis in post-menopausal women was found, we have focused this review on the paracrine and endocrine role of adipose tissue in breast cancer initiation and progression. As important inter-species differences in adipose tissue occur, we mainly selected human adipose tissue- and breast cancer-based studies with a short reflection on therapeutic possibilities. This review is part of the special issue on “Adiposopathy in Cancer and (Cardio)Metabolic Diseases”.
The effect of resonance on the linear sampling method
Authors: Haghparast Maysam , Mirtaheri Seyyed A. , Abrishamian Mohammad S. 
Published: July 2015

Abstract
Resonance frequency is examined for its effect on the linear
sampling method (LSM). The aim of the study is to present an evaluation of
occurrence of anomaly at some special frequencies in the LSM procedure. A
comprehensive survey is done to analyze the destructive effect of resonance
for LSM analysis. Analytical resonance calculations are used to verify the
claim. Finally, a frequency selection method is proposed in order to
overcome this phenomenon.
RSOA-Based Full-Duplex WDM-PON for 20 Gbps Transmission in Two Channels Over a Long-Haul SMF Using External Modulation Scheme
Authors: Das Anindya Sundar , Patra Ardhendu Sekhar 
Published: July 2015

AbstractWe have proposed and demonstrated a full-duplex wavelength division multiplexed passive optical network (WDM-PON) configuration based on reflective semiconductor optical amplifier (RSOA). RSOA is used for reusing and remodulate the downlink signal in the uplink. We have used external modulation scheme for transmitting 20 Gbps data rates in two channels over a 40 km single mode fiber (SMF). The uplink and the downlink performances are checked by the bit error rate (BER) and the eye diagrams.
Der Krieg und die Liebe – Untersuchungen zur römischen Venus
Authors: Bolder-Boos Marion 
Published: July 2015

ZusammenfassungIn der ausgehenden römischen Republik gehörte die Göttin Venus zu Roms bedeutendsten Gottheiten: sowohl Sulla als auch Pompeius hatten sie zu ihrer persönlichen Schutzgöttin erkoren, und Caesar feierte sie als seine göttliche Stammmutter. Die enorme Popularität der Venus wird oftmals mit ihrer Rolle als Mutter des Aeneas, dessen Mythos durch den zunehmenden Kontakt der Römer mit den Griechen im Verlauf des 2. Jh.s v. Chr. immer mehr an Bedeutung gewann, in Verbindung gebracht. Die römische Venus besaß jedoch auch Qualitäten, die sich von denen ihres griechischen Gegenparts, Aphrodite, deutlich unterschieden. Neben Verbindungen zu Liebe und Sexualität offenbart Venus etwa heilende Kräfte, die sie in die Nähe altitalischer Göttinnen wie Mefitis, Cloacina oder Libitina rücken. Auch kriegerische Charakterzüge sind nachweisbar.Im Folgenden sollen diese verschiedenen Züge der römischen Venus in republikanischer Zeit eingehender untersucht werden, um die Komplexität dieser bedeutenden Göttin zu erklären, die nicht nur durch griechische und etruskische, sondern auch italische und orientalische Einflüsse geprägt war, und die keinesfalls eine reine „Göttin der Liebe“ darstellte.
Selbstbehauptung des Geistes. Richard Kroner und Paul Tillich – die Korrespondenz
Authors: Christophersen Alf , Graf Friedrich Wilhelm 
Published: July 2015

AbstractThis edition makes available the correspondence between Paul Tillich and his friend, the philosopher Richard Kroner, who were colleagues at the Technische Universität Dresden from the winter semester of 1925/26. They were to meet again in New York after Tillich's emigration to the United States in 1933, and Kroner's six years later. In 1941 Tillich was able to secure Kroner a visiting lecturer position at Union Theological Seminary. The exchange of letters, which also includes contributions from their wives Hannah Tillich and Alice Kroner, covers the period from 1942 to 1964. It offers a remarkable account of the struggle for self-assertion and reorientation of two very different personalities who escaped the destructive will of the National Socialists. While Kroner and Tillich shared an enthusiasm for the philosophical legacy of German Idealism, they expressed it very differently in their respective works.
Successful treatment of neonatal severe hyperparathyroidism with cinacalcet in two patients
Authors: Fisher Marisa M , Cabrera Susanne M , Imel Erik A 
Published: July 2015

Summary
Neonatal severe hyperparathyroidism (NSHPT) is a rare disorder caused by inactivating calcium-sensing receptor (CASR) mutations that result in life-threatening hypercalcemia and metabolic bone disease. Until recently, therapy has been surgical parathyroidectomy. Three previous case reports have shown successful medical management of NSHPT with cinacalcet. Here we present the detailed description of two unrelated patients with NSHPT due to heterozygous R185Q CASR mutations. Patient 1 was diagnosed at 11 months of age and had developmental delays, dysphagia, bell-shaped chest, and periosteal bone reactions. Patient 2 was diagnosed at 1 month of age and had failure to thrive, osteopenia, and multiple rib fractures. Cinacalcet was initiated at 13 months of age in patient 1, and at 4 months of age in patient 2. We have successfully normalized their parathyroid hormone and alkaline phosphatase levels. Despite the continuance of mild hypercalcemia (11–12 mg/dl), both patients showed no hypercalcemic symptoms. Importantly, patient 1 had improved neurodevelopment and patient 2 never experienced any developmental delays after starting cinacalcet. Neither experienced fractures after starting cinacalcet. Both have been successfully managed long-term without any significant adverse events. These cases expand the current literature of cinacalcet use in NSHPT to five successful reported cases. We propose that cinacalcet may be considered as an option for treating the severe hypercalcemia and metabolic bone disease found in infants and children with inactivating CASR disorders.

Learning points

NSHPT due to mutations in the CASR gene occurs with hypercalcemia and metabolic bone disease, but not always with severe critical illness in infancy.

NSHPT should be considered in the differential diagnosis for a newborn with a bell-shaped chest, osteopenia, and periosteal reactions.

Neurodevelopmental consequences may occur in children with hypercalcemia and may improve during treatment.

Calcimimetics can be used to successfully treat the pathophysiology of NSHPT directly to control serum calcium levels.
Screening for Speech and Language Delay in Children 5 Years Old and Younger: A Systematic Review
Authors: Wallace Ina F. , Berkman Nancy D. , Watson Linda R. , Coyne-Beasley Tamera , Wood Charles T. , Cullen Katherine , Lohr Kathleen N. 
Published: July 2015

BACKGROUND AND OBJECTIVES:No recommendation exists for or against routine use of brief, formal screening instruments in primary care to detect speech and language delay in children through 5 years of age. This review aimed to update the evidence on screening and treating children for speech and language since the 2006 US Preventive Services Task Force systematic review.METHODS:Medline, the Cochrane Library, PsycInfo, Cumulative Index to Nursing and Allied Health Literature, ClinicalTrials.gov, and reference lists. We included studies reporting diagnostic accuracy of screening tools and randomized controlled trials reporting benefits and harms of treatment of speech and language. Two independent reviewers extracted data, checked accuracy, and assigned quality ratings using predefined criteria.RESULTS:We found no evidence for the impact of screening on speech and language outcomes. In 23 studies evaluating the accuracy of screening tools, sensitivity ranged between 50% and 94%, and specificity ranged between 45% and 96%. Twelve treatment studies improved various outcomes in language, articulation, and stuttering; little evidence emerged for interventions improving other outcomes or for adverse effects of treatment. Risk factors associated with speech and language delay were male gender, family history, and low parental education. A limitation of this review is the lack of well-designed, well-conducted studies addressing whether screening for speech and language delay or disorders improves outcomes.CONCLUSIONS:Several screening tools can accurately identify children for diagnostic evaluations and interventions, but evidence is inadequate regarding applicability in primary care settings. Some treatments for young children identified with speech and language delays and disorders may be effective.
Screening for Speech and Language Delay and Disorders in Children Aged 5 Years or Younger: US Preventive Services Task Force Recommendation Statement
Authors: Siu Albert L. 
Published: July 2015

BACKGROUND:
This report is an update of the US Preventive Services Task Force (USPSTF) 2006 recommendation on screening for speech and language delay in preschool-aged children.

METHODS:
The USPSTF reviewed the evidence on screening for speech and language delay and disorders in children aged 5 years or younger, including the accuracy of screening in primary care settings, the role of surveillance by primary care clinicians, whether screening and interventions lead to improved outcomes, and the potential harms associated with screening and interventions.

POPULATION:
This recommendation applies to asymptomatic children aged 5 years or younger whose parents or clinicians do not have specific concerns about their speech, language, hearing, or development.

RECOMMENDATION:
The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of screening for speech and language delay and disorders in children aged 5 years or younger (I statement).
Gorgonias (Octocorallia: Gorgoniidae) de las aguas someras del Pacífico Norte de Costa Rica
Authors: Breedy Odalisca , Cortés Jorge 
Published: July 2015

<p>Los octocorales son componentes abundantes y característicos de las aguas someras sobre promontorios rocosos y arrecifes de coral. Se ha informado sobre la riqueza de especies de octocorales de Pacífico de Costa Rica en diversas publicaciones taxonómicos. Sin embargo, no han sido estudiados en cuanto a su ecología, especialmente por los problemas que representa el reconocimiento de las especies, especialmente en el campo y el difícil acceso a las localidades para este tipo de investigación. En 2012 como parte del proyecto <em>Estudios científicos en el área costera del Pacífico Norte, Costa Rica</em> para evaluar el estado de las comunidades coralinas de las aguas someras tuvimos la oportunidad de explorar algunos sitios (menos de 35 m de profundidad) y evaluar la fauna de Octocorallia. Se registró la presencia y la riqueza de especies. Se encontraron cuatro especies en el género <em>Eugorgia</em>, nueve en <em>Leptogorgia</em> y 10 en <em>Pacifigorgia</em>. El objetivo de este trabajo es registrar las especies de octocorales encontradas y facilitar la identificación de esta fauna por medio de la elaboración de una clave para futuros estudios. Las especies se identificaron y caracterizaron morfológicamente, se ilustran con fotografías submarinas, de especímenes preservados y de sus escleritas (estructuras esqueléticas que forman la colonia, que se utilizan en su diferenciación taxonómica).</p><div> </div>
Aprender haciendo: Uso de una estrategia didáctica en un curso avanzado de la carrera de Farmacia de la Universidad de Costa Rica
Authors: León-Salas Angie 
Published: July 2015

El presente artículo describe la implementación de la estrategia didáctica del aprendizaje orientado en proyectos (AOP) con el objetivo de promover el aprendizaje de aspectos básicos de prevención de la enfermedad y promoción de la salud, lo anterior con el fin de impulsar el desarrollo de habilidades para la participación en intervenciones de salud pública. Estudiantes del último año de la carrera de Licenciatura en Farmacia de la Universidad de Costa Rica realizaron, durante 3 semanas, un proyecto en el cual identificaron y abordaron un problema de salud que afectaba a su grupo de clase. Se incluyó el desarrollo de una intervención por parte del estudiantado y la respuesta de cuestionarios en línea que evaluaron su propia percepción antes y después de la implementación de la estrategia. La retroalimentación brindada por el estudiantado fue positiva y apoya el desarrollo de acciones dinámicas para fortalecer el proceso de aprendizaje. Se concluye que el uso del AOP permitió analizar los contenidos teóricos de una manera aplicada. Es necesario hacer consideraciones de tiempo y evaluación con el fin de darle continuidad a la actividad propuesta.
Structural style and evolution of the Pyrenean-Provence thrust belt, SE France
Authors: Bestani Lucie , Espurt Nicolas , Lamarche Juliette , Floquet Marc , Philip Jean , Bellier Olivier , Hollender Fabrice 
Published: July 2015

AbstractThe Pyrenean-Provence fold-thrust belt is characterized by a geological complexity arising from superimposed tectonic history and the propagation of the deformation through a heterogeneous mechanical substratum inherited from Paleozoic and Mesozoic times. The construction of a regional balanced cross section together with field data show that the thrust system of the southeastern Provence region is characterized by a mixed thick- and thin-skinned tectonic style related to the inversion of deep-seated late Paleozoic-Triassic extensional structures and the décollement of the Mesozoic-Cenozoic sedimentary cover above Triassic series. Earliest Cenomanian restoration state highlights the northward pinched-out of the Lower Cretaceous sedimentary series above the main long-wavelength Durance High uplift. Latest Santonian restoration state indicates a southward tilting of ~2° of the basin attributed to the initial growth of the Pyrenean-Provence prism controlling the external flexure of the foreland. Thrusts propagation in the northern part of the Pyrenean-Provence fold-thrust belt was recorded to be synchronous during latest Cretaceous to Eocene time and produced a ~7° southward basin tilting. This major tilting is attributed to the tectonic inversion and basement thrust stacking of the Cap Sicié-Sainte Baume units. Cross section balancing shows a total horizontal basement shortening of 40 km (~35 %) across the Pyrenean-Provence foreland. The main part of this shortening (~37 km) was accommodated by thick-skinned thrusts involving basement south of the Arc syncline. ~5 km of shortening were accommodated northward by the Arc syncline and eastern Sainte-Victoire thin-skin structures, resulting from slip transferred from the deep thick-skinned intercutaneous thrust wedge. Finally we interpret salt tectonic structures of the southeastern Provence as passive diapirism growth during Jurassic to late Cretaceous time, and then reactivated during Pyrenean-Provence compression. Late normal faulting related to hypothetical reactive diapirism during the Oligocene extension episode was predominantly localized above inherited salt structures and probably controlled by inherited basement faults.
Post-rift evolution of the Gulf of Lion margin tested by stratigraphic modelling
Authors: Leroux Estelle , Rabineau Marina , Aslanian Daniel , Gorini Christian , Bache François , Moulin Maryline , Pellen Romain , Granjeon Didier , Rubino Jean-Loup 
Published: July 2015

AbstractThe sedimentary architecture of basins and passive margins is determined by a complex interaction of parameters, including subsidence, eustasy, and sediment supply. A quantification of the post-rift (20 Ma-0 Ma) vertical movements of the Gulf of Lion (West Mediterranean) is proposed here based on the stratigraphic study of sedimentary paleomarkers using a large 3D grid of reflection seismic data, correlations with existing drillings, and refraction data. Post-rift subsidence was measured by the direct use of sedimentary geometries analysed in 3D and validated by numerical stratigraphic modelling. Three domains of subsidence were found: on the continental shelf and slope, subsidence corresponds to a seaward tilting with different amplitudes, whereas the deep basin subsides purely vertically. We show that these domains fit with the deeper crustal domains highlighted by previous geophysical data, and that post-break-up subsidence follows the initial hinge lines of the rifting phase. Subsidence rates are quantified on each domain for each stratigraphic interval. At a constant distance from the rotational hinge line, the Plio-Quaternary subsidence rate is constant on the shelf overall. Conversely, Miocene subsidence rates are very different on the eastern and western shelves. Stratigraphic simulations focused on the Messinian salinity crisis (MSC) were also performed. Their results are discussed together with our post-rift subsidence estimates in order to provide ideas and hypotheses for future detailed quantifications of Miocene subsidence, including isostatic readjustments linked to the MSC.
Deep crustal structure across a young passive margin from wide-angle and reflection seismic data (The SARDINIA Experiment) – II. Sardinia’s margin
Authors: Afilhado Alexandra , Moulin Maryline , Aslanian Daniel , Schnürle Philippe , Klingelhoefer Frauke , Nouzé Hervé , Rabineau Marina , Leroux Estelle , Beslier Marie-Odile 
Published: July 2015

Abstract
Geophysical data acquired on the conjugate margins system of the Gulf of Lion and West Sardinia (GLWS) is unique in its ability to address fundamental questions about rifting (i.e. crustal thinning, the nature of the continent-ocean transition zone, the style of rifting and subsequent evolution, and the connection between deep and surface processes).
While the Gulf of Lion (GoL) was the site of several deep seismic experiments, which occurred before the SARDINIA Experiment (ESP and ECORS Experiments in 1981 and 1988 respectively), the crustal structure of the West Sardinia margin remains unknown. This paper describes the first modeling of wide-angle and near-vertical reflection multi-channel seismic (MCS) profiles crossing the West Sardinia margin, in the Mediterranean Sea. The profiles were acquired, together with the exact conjugate of the profiles crossing the GoL, during the SARDINIA experiment in December 2006 with the French R/V L’Atalante.
Forward wide-angle modeling of both data sets (wide-angle and multi-channel seismic) confirms that the margin is characterized by three distinct domains following the onshore unthinned, 26 km-thick continental crust : Domain V, where the crust thins from ~26 to 6 km in a width of about 75 km; Domain IV where the basement is characterized by high velocity gradients and lower crustal seismic velocities from 6.8 to 7.25 km/s, which are atypical for either crustal or upper mantle material, and Domain III composed of “atypical” oceanic crust.
The structure observed on the West Sardinian margin presents a distribution of seismic velocities that is symmetrical with those observed on the Gulf of Lion’s side, except for the dimension of each domain and with respect to the initiation of seafloor spreading. This result does not support the hypothesis of simple shear mechanism operating along a lithospheric detachment during the formation of the Liguro-Provencal basin.