bluuebunny/crossref_metadata_2025_split huggingface dataset:
Combined pelvic muscle exercise and yoga program for urinary incontinence in middle‐aged women
Authors: Kim Gwang Suk , Kim Eun Gyeong , Shin Ki Young , Choo Hee Jung , Kim Mi Ja 
Published: February 2015

AbstractAimUrinary incontinence is a major health problem among middle‐aged women. Pelvic muscle exercise is one of the primary interventions, but difficulty performing this exercise has led researchers to seek alternative or conjunctive exercise. This study aimed to examine the effect of a combined pelvic muscle exercise and yoga intervention program on urinary incontinence.MethodsA single group pre‐/post‐test design was used. Subjects were recruited from a community health center in Seoul, Korea, and a questionnaire survey was conducted. Fifty‐five women participated in the first day of the program, 34 of whom completed the 8 week, twice weekly intervention program. Urinary incontinence was measured by five domains of urinary tract symptoms: filling factor, voiding factor, incontinence factor, sexual function, and quality of life. Also measured were attitude toward pelvic muscle exercise and pelvic muscle strength.ResultsSignificant improvements were found in attitude toward pelvic muscle exercise, pelvic muscle strength, and incontinence factor. Daily performance of pelvic muscle exercise was positively correlated with improved incontinence factor and with quality of life related to urinary tract symptoms.ConclusionA combined pelvic muscle exercise and yoga program was effective for improving overall urinary incontinence in community health center attendees in Korea. Further study is needed with a control group, different populations, and a longer intervention period.
Integrating self‐control with physical attractiveness and cognitive ability to examine pathways to career success
Authors: Converse Patrick D. , Thackray Michelle , Piccone Katrina , Sudduth Mary Margaret , Tocci Michael C. , Miloslavic Stephanie A. 
Published: February 2015

Physical attractiveness, cognitive ability, and self‐control predict many important outcomes but are rarely examined in combination, particularly in the context of career success. Drawing from Judge et al.'s (2009, J. Appl. Psychol., 94, 742) model of income antecedents and Caspi et al.'s (1989, J. Pers., 57, 375) concepts of cumulative and interactional continuity, this study investigated the pathways leading from these characteristics to career outcomes. Specifically, we developed a model with links involving (1) attractiveness, intelligence, and self‐control; (2) self‐evaluations, delinquent behaviours, educational attainment, and job complexity; and (3) income and job satisfaction. The model was examined with data from three waves of the National Longitudinal Study of Adolescent Health. Results supported a slightly modified model, with major findings indicating attractiveness, intelligence, and self‐control measured during adolescence predicted later self‐evaluations or delinquent behaviour; these variables predicted later education level; education level predicted job complexity; and job complexity predicted income and job satisfaction. Implications related to this integrated model are discussed.Practitioner points

Interventions might focus on enhancing self‐control‐related skills in adolescents in an effort to improve later work‐related outcomes.

Core self‐evaluations and delinquent tendencies could also be targeted during adolescence to influence life pathways relevant to career outcomes.
Development of Microsatellite Markers for Miiuy Croaker, Miichthys miiuy (Sciaenidae), and Their Application in Verifying Gynogenesis of Large Yellow Croaker, Pseudosciaena crocea, Induced with M. miiuy Sperm
Authors: Miao Liang , Li Ming‐Yun , Chen Ying‐Ying , Guo Xiao‐Fei , Xu Yu‐Min , Li Xiao‐Meng , Chen Jiong 
Published: February 2015

AbstractA total of 30 microsatellite markers were isolated from miiuy croaker, Miichthys miiuy, and characterized. Of these, 24 were polymorphic with an average of 4.33 alleles per locus (range: 2–8). The observed (Ho) and expected (He) heterozygosities ranged from 0.0667 to 1.0000 (mean: 0.6361) and 0.3828 to 0.8139 (mean: 0.6443), respectively. The mean polymorphism information content (PIC) value was 0.576, ranging from 0.348 to 0.823. Eight loci deviated significantly from the Hardy–Weinberg equilibrium (HWE). Twelve of the 30 primer pairs amplified DNA sequences of large yellow croaker, Pseudosciaena crocea, and 10 were polymorphic. Except for MM007, sequence alignments of microsatellite flanking regions of the other 11 loci were highly similar between the two species. The gynogenetic P. crocea induced by the sperm of M. miiuy were verified using four cross‐amplified primer pairs. No specific paternal bands were found in the offspring, indicating exclusive maternal inheritance.
Accumulation of transportin 1 in the fused in sarcoma‐positive neuronal inclusions in sporadic amyotrophic lateral sclerosis without FUS mutation
Authors: Tokushige Shin‐ichi , Sasaki Takuya , Hatsuta Hiroyuki , Uchino Akiko , Kakuta Yukio , Shimizu Jun , Tsuji Shoji , Nakayama Takahiro , Imafuku Ichiro , Murayama Shigeo 
Published: February 2015

AbstractWe describe a female patient with sporadic amyotrophic lateral sclerosis (ALS) with fused in sarcoma (FUS)‐immunoreactive neuronal inclusions. She presented with weakness mainly in the upper extremities that had started at the age of 53 years. She died at the age of 61 years. Neuronal loss and gliosis accompanying FUS‐positive neuronal cytoplasmic inclusions involved the upper and lower motor neurons, brainstem motor neurons, basal ganglia, substantia nigra, cerebellar dentate nuclei, thalamus, hypothalamic nuclei, and red nuclei. Most of these inclusions were positive for transportin 1, in a pattern similar to frontotemporal lobar degeneration with FUS and different from familial ALS‐FUS. Mutational analysis showed no mutations in the FUS gene. Our findings show that transportin 1 accumulates in the FUS‐positive inclusions in sporadic ALS‐FUS.
Irritable bowel syndrome: an integrated explanatory model for clinical practice
Authors: Hungin A. P. S. , Becher A. , Cayley B. , Heidelbaugh J. J. , Muris J. W. M. , Rubin G. , Seifert B. , Russell A. , De Wit N. J. 
Published: February 2015

AbstractBackgroundAlthough irritable bowel syndrome (IBS) is a symptom‐based diagnosis, clinicians' management of and communication about the disorder is often hampered by an unclear conceptual understanding of the nature of the problem. We aimed to elucidate an integrated explanatory model (EM) for IBS from the existing literature for pragmatic use in the clinical setting.MethodsSystematic and exploratory literature searches were performed in PubMed to identify publications on IBS and EMs.Key ResultsThe searches did not identify a single, integrated EM for IBS. However, three main hypotheses were elucidated that could provide components with which to develop an IBS EM: (i) altered peripheral regulation of gut function (including sensory and secretory mechanisms); (ii) altered brain–gut signaling (including visceral hypersensitivity); and (iii) psychological distress. Genetic polymorphisms and epigenetic changes may, to some degree, underlie the etiology and pathophysiology of IBS and could increase the susceptibility to developing the disorder. The three model components also fit into one integrated explanation for abdominal symptoms and changes in stool habit. Additionally, IBS may share a common pathophysiological mechanism with other associated functional syndromes.Conclusions & InferencesIt was possible to elucidate an integrated, three‐component EM as a basis for clinicians to conceptualize the nature of IBS, with the potential to contribute to better diagnosis and management, and dialog with sufferers.
Laser therapy reduces gelatinolytic activity in the rat trigeminal ganglion during temporomandibular joint inflammation
Authors: Desiderá AC , Nascimento GC , Gerlach RF , Leite‐Panissi CRA 
Published: February 2015

ObjectivesTo investigate whether low‐level laser therapy (LLLT) alters the expression and activity of MMP‐2 and MMP‐9 in the trigeminal ganglion (TG) during different stages of temporomandibular joint (TMJ) inflammation in rats. It also evaluated whether LLLT modifies mechanical allodynia and orofacial hyperalgesia.Materials and MethodsWistar rats (±250 g) were divided into groups that received saline (SAL) or complete Freund's adjuvant (CFA, 50 μl) in the TMJ, and that later underwent LLLT (20 J cm−2) at their TMJ or not (groups SAL, SAL + LLLT, CFA, and CFA + LLLT). LLLT was applied on days 3, 5, 7, and 9 after SAL or CFA. Mechanical allodynia was evaluated on days 1, 3, 5, 7, and 10; orofacial hyperalgesia was assessed on day 10. Gelatin zymography and in situ zymography aided quantification of MMPs in the TG.ResultsLow‐level laser therapy abolished the reduction in the mechanical orofacial threshold and the increase in orofacial rubbing during the orofacial formalin test induced by CFA. LLLT also decreased the CFA‐induced rise in the levels of MMP‐9 and MMP‐2 as well as the gelatinolytic activity in the TG.ConclusionLow‐level laser therapy could constitute an adjuvant therapy to treat temporomandibular disorders and prevent inflammation‐induced alterations in the levels of MMP‐2 and MMP‐9 and in the gelatinolytic activity in TGs.
What lessons can be learned about asthma phenotypes in children from cohort studies?
Authors: Just J. , Saint Pierre P. , Amat F. , Gouvis‐Echraghi R. , Lambert‐Guillemot N. , Guiddir T. , Annesi Maesano I. 
Published: February 2015

Abstract‘Phenotyping’ asthma by multivariate analyses and more recently by unsupervised analysis has been performed in children cohorts. We describe the key findings that have emerged from these cohorts. It would appear that there are three wheeze phenotypes in children of preschool age: the mild episodic viral wheeze phenotype; the multitrigger atopic wheeze; and, less often encountered, the severe non‐atopic wheeze. Early onset of allergy in asthma (more prevalent in boys) is associated with poor prognosis unlike the severe non‐atopic wheeze phenotype which has a female predominance. The prognosis of the severe non‐atopic wheeze depends on time of onset (early or late) of allergic expression. At school age, the risk of severe asthmatic exacerbations is associated with eosinophil predominant inflammation frequently related to allergic asthma, whereas neutrophil inflammation is associated with moderate‐to‐severe asthma with poorer lung function. Nevertheless, allergic asthma is also a heterogeneous disease with a severe allergic phenotype strongly associated with atopic dermatitis and very high eosinophil‐driven inflammatory markers. Further studies are required to find non‐invasive biological markers in very young children to better define wheezing phenotypes associated with an elevated risk of developing severe asthma with a view to personalizing treatment.
Crowding Out or Welfare Promotion? How Foreign Aid Affects Social Expenditures in Latin American Welfare Systems
Authors: Berens Sarah A. 
Published: February 2015

AbstractForeign assistance constitutes a significant share of government revenue in many low‐ and middle‐income economies and is targeted at poverty reduction and the promotion of social and economic well‐being. This study therefore examines fiscal responses by Latin American welfare states to the inflow of such aid. As a form of external non‐tax revenue, aid can function as a substitution for public welfare expenditure, with a crowding out effect being the likely outcome. This article investigates whether overall aid and aid that is particularly targeted at the social sector substitutes public welfare provision and, if so, whether it also substitutes its function. A time‐series cross‐section analysis of 19 Latin American countries for the period 1980–2008 provides limited support for the assumption that foreign aid payments influence the welfare budget. It is only the health care sector in middle‐income countries which experiences a small decrease in expenditures. Social security and education expenditures are not affected.
Effect of active infection on cytochrome P450‐mediated metabolism of cyclosporine in renal transplant patients
Authors: Hegazy S.K. , Adam A.G. , Hamdy N.A. , Khalafallah N.M. 
Published: February 2015

AbstractBackgroundInfections downregulate cytochrome‐P activities and thus may alter drug disposition, especially for drugs with a narrow therapeutic index. Cyclosporine (CyA), still used for the prevention of allograft rejection in renal transplant recipients in Egypt, seems to be affected by these infectious changes, based on random clinical observations. In the present study, the effects of bacterial and fungal infection on CyA metabolism were studied in renal transplant patients and subsequent nephrotoxicity was monitored.MethodsTwenty renal transplant patients, diagnosed with fungal or bacterial infection, were recruited from the renal transplantation outpatient clinic in Alexandria University Hospitals. No dose adjustment in CyA was performed at least 1 week before the onset of infection. Exclusion criteria were patients with acute or chronic unstable liver disease, elderly patients, and patients on concomitant drugs affecting CyA metabolism. CyA trough levels and serum creatinine (SCR) concentrations were measured by fluorescence polarization immunoassay and enzymatic assay, respectively, pre‐infection, during infection and in many cases, post infection.ResultsCyA trough levels and SCR concentrations increased significantly during the infection (P < 0.001, P = 0.002) respectively. Of the patients, 87% experienced a concomitant rise in CyA trough level and SCR concentrations. No significant difference between pre‐infection and post‐infection levels of CyA trough and SCR was found.ConclusionsCyA trough and SCR levels increased during bacterial and fungal infections and returned to pre‐infection levels once the infection was resolved. The data generated stress the importance of monitoring CyA levels during episodes of infection. Our recommendations concerning CyA dose adjustment differ according to severity and duration of infection.
Adverse Drug Reaction reports for cardiometabolic drugs from sub‐Saharan Africa: a study in VigiBase
Authors: Berhe Derbew Fikadu , Juhlin Kristina , Star Kristina , Beyene Kidanemariam G. M. , Dheda Mukesh , Haaijer‐Ruskamp Flora M. , Taxis Katja , Mol Peter G. M. 
Published: February 2015

AbstractObjectiveIdentifying key features in individual case safety reports (ICSR) of suspected adverse drug reactions (ADRs) with cardiometabolic drugs from sub‐Saharan Africa (SSA) compared with reports from the rest of the world (RoW).MethodsReports on suspected ADRs of cardiometabolic drugs (ATC: A10[antidiabetic], B01[antithrombotics] and C[cardiovascular]) were extracted from WHO Global database, VigiBase®(1992–2013). We used vigiPoint, a logarithmic odds ratios (log2 OR)‐based method to study disproportional reporting between SSA and RoW. Case‐defining features were considered relevant if the lower limit of the 99% CI > 0.5.ResultsIn SSA, 3773 (9%) of reported ADRs were for cardiometabolic drugs, in RoW for 18%. Of these, 79% originated from South Africa and 81% were received after 2007. Most reports were for drugs acting on the renin–angiotensin system (36% SSA & 14% RoW). Compared with RoW, reports were more often sent for patients 18–44 years old (log2 OR 0.95 [99 CI 0.80; 1.09]) or with non‐fatal outcome (log2 OR 1.16 [99 CI 1.10; 1.22]). Eight ADRs (cough, angioedema, lip swelling, face oedema, swollen tongue, throat irritation, drug ineffective and blood glucose abnormal) and seven drugs (enalapril, rosuvastatin, perindopril, vildagliptin, insulin glulisine, nifedipine and insulin lispro) were disproportionally more reported in SSA than in the RoW.Conclusions‘In recent years, the number of adverse drug reactions (ADRs) reported in Sub‐Saharan Africa (SSA) has sharply increased. The data showed the well‐known population‐based differential ADR profile of ACE inhibitors in the SSA population.’
Platelet transfusion and catheter insertion for plasma exchange in patients with thrombotic thrombocytopenic purpura and a low platelet count
Authors: Riviere Etienne , Saint‐Léger Mélanie , James Chloé , Delmas Yahsou , Clouzeau Benjamin , Bui Nam , Vital Anne , Coppo Paul , Gruson Didier , Boyer Alexandre 
Published: February 2015

BACKGROUNDIn thrombotic thrombocytopenic purpura (TTP), platelet (PLT) transfusion is contraindicated unless a life‐threatening hemorrhage occurs. However, when PLT count is low (<20 × 109/L), their benefit–risk balance before central venous catheter (CVC) insertion for plasma exchange (PE) has not specifically been addressed in guidelines.CASE REPORTSWe report two cases in which PLTs were transfused before CVC insertion for PE, resulting in fatal myocardial infarction or neurologic complications.DISCUSSIONTo date, there is a paucity of high‐quality, evidence‐based information on prophylactic PLT transfusion for CVC placement in TTP. Several monocenter series report that CVC could be inserted safely without PLT transfusion by experienced teams under ultrasound guidance. Uncertainty makes most physicians uncomfortable with this decision and this is a common reason why PLT transfusion remains a “precautionary” albeit misguided position.CONCLUSIONWe propose a practical algorithm to avoid unnecessary PLT transfusion before CVC insertion for rapid PE in the initial management of TTP patients. We recommend no prophylactic PLT transfusion but CVC insertion in a compressible vein under ultrasound guidance by an experienced team or quick PE started on two peripheral veins if possible. PLTs should only be transfused in case of severe bleeding in association with plasma infusion and CVC insertion for immediate PE.
Construction of spline curves on smooth manifolds by action of Lie groups
Authors: Pobegailo A. P. 
Published: February 2015

AbstractPolynomials for blending parametric curves in Lie groups are defined. Properties of these polynomials are proved. Blending parametric curves in Lie groups with these polynomials is considered. Then application of the proposed technique to construction of spline curves on smooth manifolds is presented. As an example, construction of spherical spline curves using the proposed approach is depicted.
Impact of ISO 9000 Quality Program on Power Generating Industry
Authors: Ullmann Klaus , Kautz Hans R. 
Published: February 2015

The objective of the ‘Roman Contracts’ concluded in 1957 was to establish a common European market, i.e. a gradual economic (and possibly political) union. This, however, required an increasing understanding that national reservations would have to be abolished and some basic measures implemented. Here European standardization plays an essential part, also with respect to harmonization — a presently very popular term in Europe. Harmonization means adaptation/standardization of the inevitably differing national, technical regulatory guides. The following milestones were decisive and determining for the harmonization of the regulatory guides:
• Various decisions of the European Court of Justice1 concerning the limitation of the national reservations;
• the new concept for the technical harmonization [1].
Genome Sequence and Annotation of Helicobacter pylori Strain Hp238, Isolated from a Taiwanese Patient with Mucosa-Associated Lymphoid Tissue Lymphoma
Authors: Kao Cheng-Yen , Chen Jenn-Wei , Huang Yi-Ting , Sheu Shew-Meei , Sheu Bor-Shyang , Wu Jiunn-Jong 
Published: February 2015

ABSTRACT

We present the complete genome sequence of
Helicobacter pylori
strain Hp238, isolated from a Taiwanese patient with gastric mucosa-associated lymphoid tissue lymphoma. Importantly,
H. pylori
strain Hp238 can multiply in THP-1 cells after internalization through the induction of autophagosome formation. These genome data will help to identify genes associated with
H. pylori
intracellular multiplication and pathogenesis.
Draft Genome Sequence of Marine-Derived Streptomyces sp. TP-A0873, a Producer of a Pyrrolizidine Alkaloid Bohemamine
Authors: Komaki Hisayuki , Ichikawa Natsuko , Hosoyama Akira , Fujita Nobuyuki , Igarashi Yasuhiro 
Published: February 2015

ABSTRACT
Streptomyces sp. TP-A0873, isolated from deep-sea water, produces three different classes of secondary metabolites: antimycin, bohemamine, and alkylated butenolides. In order to assess the biosynthetic potential of this strain, draft genome sequencing was carried out. The genome contained at least 14 gene clusters for polyketide synthase (PKS) and nonribosomal peptide synthetase (NRPS).
Draft Genome Sequence of
Phomopsis longicolla
Type Strain TWH P74, a Fungus Causing Phomopsis Seed Decay in Soybean
Authors: Li Shuxian , Song Qijian , Ji Pingsheng , Cregan Perry 
Published: February 2015

ABSTRACT

Phomopsis longicolla
is the primary cause of Phomopsis seed decay in soybean. Here, we report the
de novo
assembled draft genome sequence of the P. longicolla type strain TWH P74 (ATCC 60325), which was originally isolated by Hobbs et al. from soybean seed in Ohio in 1983.
Genome Sequence of Arthrobacter sp. MWB30, Isolated from a Crude Oil-Contaminated Seashore
Authors: Kim Jonghyun , Kim Soo Jung , Kim Seon Hee , Moon Yoon-Jung , Park Sung-Joon , Kim Seung Il , Kahng Hyung-Yeel , Chung Young-Ho 
Published: February 2015

ABSTRACT
We report here the draft genome sequence of Arthrobacter sp. MWB30 strain, isolated from a crude oil-contaminated seashore in Tae-an, South Korea, which is able to degrade the crude oil and its derivatives. The draft genome sequence of 4,647,008 bp provides a resource for the identification of crude oil-degrading mechanisms in strain MWB30.
Analysis of Quorum-Sensing Pantoea stewartii Strain M073a through Whole-Genome Sequencing
Authors: Mohamad Nur Izzati , Tan Wen-Si , Chang Chien-Yi , Tee Kok Keng , Yin Wai-Fong , Chan Kok-Gan 
Published: February 2015

ABSTRACT

Pantoea stewartii
strain M073a is a Gram-negative bacterium isolated from a tropical waterfall. This strain exhibits quorum-sensing activity. Here, the assembly and annotation of its genome are presented.
Complete Genome Sequence of Campylobacter fetus subsp.
testudinum
Strain Pet-3, Isolated from a Lizard (Hydrosaurus pustulatus)
Authors: Wang Chao-Min , Wu Zong-Yen , Shia Wei-Yau , Jhou Yi-Jyun , Tung Kwong-Chung , Shyu Ching-Lin 
Published: February 2015

ABSTRACT

The whole-genome sequence for
Campylobacter fetus
subsp.
testudinum
, a pathogen isolated from humans and turtles, has been reported recently. We present another completed genome sequence of the
C. fetus
subsp.
testudinum
strain pet-3, which was isolated from a lizard in Taiwan, for further genomic comparison study.
Sequence Analysis of Staphylococcus hyicus ATCC 11249
T
, an Etiological Agent of Exudative Epidermitis in Swine, Reveals a Type VII Secretion System Locus and a Novel 116-Kilobase Genomic Island Harboring Toxin-Encoding Genes
Authors: Calcutt Michael J. , Foecking Mark F. , Hsieh Hsin-Yeh , Adkins Pamela R. F. , Stewart George C. , Middleton John R. 
Published: February 2015

ABSTRACT

Staphylococcus hyicus
is the primary etiological agent of exudative epidermitis in swine. Analysis of the complete genome sequence of the type strain revealed a locus encoding a type VII secretion system and a large chromosomal island harboring the genes encoding exfoliative toxin ExhA and an EDIN toxin homolog.
Draft Genome Sequence of
Rhodobacteraceae
Strain PD-2, an Algicidal Bacterium with a Quorum-Sensing System, Isolated from the Marine Microalga
Prorocentrum donghaiense
Authors: Zheng Li , Cui Zhisong , Xu Luyan , Sun Chengjun , Powell Ryan J. , Hill Russell T. 
Published: February 2015

ABSTRACT

Rhodobacteraceae
strain PD-2 was isolated from the marine microalga
Prorocentrum donghaiense
. It has algicidal activity toward its host and could produce
N
-acylhomoserine lactone signals. Here, we present the draft genome of strain PD-2, which contains 5,227,214 bp with an average GC content of 66.19%. There were 4,864 encoding gene sequences and two clusters of
luxI
and
luxR
homologues identified.