bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Generation of Stereochemically Defined Tetrasubstituted Enolborinates by 1,4‐Hydroboration of α,β‐Unsaturated Morpholine Carboxamides with (Diisopinocampheyl)borane.
Authors: Allais Christophe , Tsai Andy S. , Nuhant Philippe , Roush William R. 
Published: April 2014

AbstractThe aldol reaction of stereodefined tetrasubstituted enolborinates, derived from the reaction of α,β‐unsaturated carboxamides with enantiopure diisopinocampheylborane, with aliphatic and aromatic aldehydes is described.
ChemInform Abstract: Oxidative Heck Coupling of Allylic Amines with 2,2,6,6‐Tetramethylpiperidine‐N‐oxyl (TEMPO) as Oxidant for the Preparation of Tetrasubstituted Alkenes.
Authors: He Zhiheng , Wibbeling Birgit , Studer Armido 
Published: April 2014

AbstractMoreover, the corresponding tetrasubstituted alkenes are obtained with complete E‐selectivity.
ChemInform Abstract: N‐Oxide as a Traceless Oxidizing Directing Group: Mild Rhodium(III)‐Catalyzed C—H Olefination for the Synthesis of ortho‐Alkenylated Tertiary Anilines.
Authors: Huang Xiaolei , Huang Jingsheng , Du Chenglong , Zhang Xingyi , Song Feijie , You Jingsong 
Published: April 2014

AbstractA novel strategy based on N‐oxide substituents as traceless directing groups is developed to achieve selective ortho C—H functionalization of N,N‐dialkylated anilines.
ChemInform Abstract: Nanoscale Fe2O3‐Based Catalysts for Selective Hydrogenation of Nitroarenes to Anilines.
Authors: Beller Matthias , et al. et al. 
Published: April 2014

AbstractPyrolysis of iron‐phenanthroline complexes on carbon furnishes a unique structure in which the active Fe2O3 particles are surrounded by a nitrogen‐doped carbon layer.
ChemInform Abstract: Iodine Catalyzed Three‐Component Synthesis of β‐Amino‐β‐keto‐esters and Their Antimicrobial Activity.
Authors: Kataki Dolly , Bhattacharyya Pranabananda , Deka Manab , Jha Dhruba Kumar , Phukan Prodeep 
Published: April 2014

AbstractNew compounds (IVb) and (IVc) show good antimicrobial activities against all the tested bacterial and fungal pathogens, however, their activities are not on par with the standard antimicrobial agents.
ChemInform Abstract: Phenyl Hydrazine as Initiator for Direct Arene C—H Arylation via Base Promoted Homolytic Aromatic Substitution.
Authors: Dewanji Abhishek , Murarka Sandip , Curran Dennis P. , Studer Armido 
Published: April 2014

AbstractIt is demonstrated that phenylhydrazine is a cheap initiator for the direct arylation of unactivated arenes with diverse aryl iodides.
ChemInform Abstract: Ag‐Promoted Azido‐Carbocyclization of Activated Alkenes via C—H Bond Cleavage.
Authors: Yuan Yizhi , Shen Tao , Wang Kui , Jiao Ning 
Published: April 2014

AbstractAn efficient silver‐promoted azido‐carbocyclization of activated alkenes leading to azido oxindoles is described.
ChemInform Abstract: Microwave‐Accelerated Pd‐Catalyzed Desulfitative Direct C2‐Arylation of Free (NH)‐Indoles with Arylsulfinic Acids.
Authors: Miao Tao , Li Pinhua , Wang Guan‐Wu , Wang Lei 
Published: April 2014

AbstractThe selective direct C2‐arylation of indoles with arylsulfinic acids proceeds through a microwave‐accelerated palladium‐catalyzed desulfitation reaction.
ChemInform Abstract: Transition Metal‐Free Regioselective C‐3 Amidation of Indoles with N‐Fluorobenzenesulfonimide.
Authors: Liu Hai‐Hong , Wang Yi , Deng Guojun , Yang Luo 
Published: April 2014

AbstractA direct transition metal‐free regioselective C‐3 amidation of electron‐deficient indoles is developed with commercially available N‐fluorobenzenesulfonimide (NFSI) as the nitrogen source.
ChemInform Abstract: A Diastereoselective Synthesis of Functionalized 3‐Pyrazolidinones from Hydrazines, Aromatic Aldehydes, and Acylketene.
Authors: Yavari Issa , Bayat Mohammad J. , Skoulika Stavroula 
Published: April 2014

AbstractAcylketene, generated in situ from 1,3‐dioxinone (I) reacts with phenylhydrazine and aromatic aldehydes to give pyrazolidinones.
ChemInform Abstract: A Photoreducible Copper(II)‐Tren Complex of Practical Value: Generation of a Highly Reactive Click Catalyst.
Authors: Harmand Lydie , Lambert Romain , Scarpantonio Luca , McClenaghan Nathan D. , Lastecoueres Dominique , Vincent Jean‐Marc 
Published: April 2014

AbstractA detailed study on the photoreduction of a copper(II) precatalyst to generate a highly reactive cuprous species for the copper(I)‐catalyzed alkyne‐azide cycloaddition (CuAAC) click reaction is presented.
ChemInform Abstract: An Iron/Amine‐Catalyzed Cascade Process for the Enantioselective Functionalization of Allylic Alcohols.
Authors: Quintard Adrien , Constantieux Thierry , Rodriguez Jean 
Published: April 2014

AbstractA novel bicatalytic system consisting of an in situ generated Fe‐complex, obtained by CO‐decoordination with Me3NO, and L‐diphenylsilylprolinol allows the transformation of allylic alcohols into β‐chiral alcohols with high enantioselectivities (up to 90% e.e.).
ChemInform Abstract: Zinc‐Mediated Addition of Diethyl Bromomalonate to Alkynes for the Cascade Reaction Towards Polysubstituted Pyranones and Tetracarbonyl Derivatives.
Authors: Miersch Anne , Harms Klaus , Hilt Gerhard 
Published: April 2014

AbstractIn case of the aryl substituted products (IVb) and (IVc) partial migration of the double bond towards the Knoevenagel product occurs.
ChemInform Abstract: Highly Regioselective α‐Arylation of Coumarins via Palladium‐Catalyzed C—H Activation/Desulfitative Coupling.
Authors: Jafarpour Farnaz , Olia Mina Barzegar Amiri , Hazrati Hamideh 
Published: April 2014

AbstractA novel regioselective α‐arylation of coumarins with readily available arenesulfonyl chlorides via palladium‐catalyzed direct C—H functionalization under mild reaction conditions is described.
ChemInform Abstract: Synthesis, Physicochemical Characterization, Cytotoxicity, Antimicrobial, Antiinflammatory and Psychotropic Activity of New N‐[1,3‐(Benzo)thiazol‐2‐yl]‐ω‐ [3,4‐dihydroisoquinolin‐2(1H)‐yl]alkanamides.
Authors: Zablotskaya Alla , Segal Izolda , Geronikaki Athina , Eremkina Tatiana , Belyakov Sergey , Petrova Marina , Shestakova Irina , Zvejniece Liga , Nikolajeva Vizma 
Published: April 2014

Abstract9 Title compounds of type (III) are prepared and tested for their anti‐inflammatory and psychotropic activities.
ChemInform Abstract: Synthesis of cis or trans 4‐Heteroaromatic Substituted Furano and Pyrano[3,2‐c]tetrahydroquinolines by One‐Pot Imino Diels—Alder Reactions.
Authors: He Gu , et al. et al. 
Published: April 2014

AbstractA mild and efficient method for the synthesis of a wide range of different substituted quinoline derivatives is developed.
ChemInform Abstract: Enantioselective Synthesis of Indoloquinolizidines via Asymmetric Catalytic Hydrogenation/Lactamization of Imino Diesters.
Authors: Liu Yong , Wang Qun , Zhang Ying , Huang Jianbiao , Nie Linlin , Chen Jie , Cao Weiguo , Wu Xiaoyu 
Published: April 2014

AbstractThe application of this method is demonstrated by total syntheses of natural alkaloids isogeissoschizol (V), geissoschizol (VI), and dihydrocorynantheol (VII).
ChemInform Abstract: Microwave‐Assisted [3 + 2] Cycloaddition and Suzuki—Miyaura Cross‐Coupling for a Concise Access to Polyaromatic Scaffolds.
Authors: Hedou Damien , Deau Emmanuel , Dubouilh‐Benard Carole , Sanselme Morgane , Martinet Anthony , Chosson Elizabeth , Levacher Vincent , Besson Thierry 
Published: April 2014

AbstractUnder these conditions a number of novel pyridopyrimidinone and quinazolinone derivatives can be prepared rapidly.
ChemInform Abstract: Synthesis and Anticancer Potential of Benzothiazole Linked Phenylpyridopyrimidinones and Their Diones as Mitochondrial Apoptotic Inducers.
Authors: Kamal Aehmed , Ashraf Md. , Vardhan M. V. P. S. Vishnu , Faazil Shaikh , Nayak V. Lakshma 
Published: April 2014

AbstractAmong the new compounds (III) and related diones (V), compound (IIIb) shows significant cytotoxicity against human cervical cancer cell line ME‐180.
ChemInform Abstract: Synthesis of Novel 7‐Substituted Pyrido[2′,3′:4,5]furo[3,2‐d]pyrimidin‐4‐amines (VII) and Their N‐Aryl Analogues (IX) and Evaluation of Their Inhibitory Activity Against Ser/Thr Kinases.
Authors: Deau Emmanuel , Loidreau Yvonnick , Marchand Pascal , Nourrisson Marie‐Renee , Loaec Nadege , Meijer Laurent , Levacher Vincent , Besson Thierry 
Published: April 2014

AbstractAmong the compounds synthesized derivative (VIIb) shows the best inhibitory activity and appears to be specific to CLK1 among the panel of the tested kinases.
ChemInform Abstract: Highly Diastereoselective NHC‐Catalyzed [4 + 3] Annulation of Enals, Aldehydes and N‐Phenyl Urea/Thiourea for the Synthesis of Monocyclic trans‐1,3‐Diazepanes.
Authors: Siddiqui Ibadur R. , Srivastava Anjali , Shamim Shayna , Srivastava Arjita , Shireen Shireen , Waseem Malik A. , Singh Rana K. P. 
Published: April 2014

AbstractUnder optimized conditions, the simple one‐pot process affords trans‐1,3‐diazepines of potential pharmaceutical interest.
ChemInform Abstract: Regiospecific N‐Heteroarylation of Amidines for Full‐Color‐Tunable Boron Difluoride Dyes with Mechanochromic Luminescence.
Authors: You Jingsong , et al. et al. 
Published: April 2014

AbstractVarious boron difluoride dyes are synthesized through a one‐pot procedure consisting of a catalytic N‐heteroarylation followed by complexation with boron trifluoride (15 examples).
ChemInform Abstract: Rhodium‐Catalyzed Oxidative C—H Activation/Cyclization for the Synthesis of Phosphaisocoumarins and Phosphorous 2‐Pyrones.
Authors: Park Youngchul , Seo Jungmin , Park Sangjune , Yoo Eun Jeong , Lee Phil Ho 
Published: April 2014

AbstractRhodium‐catalyzed cyclizations of phosphinic acids and phosphonic monoesters with alkynes are developed.
ChemInform Abstract: Cross‐Hetero‐Dehydrogenative Coupling Reaction of Phosphites: A Catalytic Metal‐Free Phosphorylation of Amines and Alcohols.
Authors: Dhineshkumar Jayaraman , Prabhu Kandikere Ramaiah 
Published: April 2014

AbstractA convenient synthesis of phosphoramidates and phosphorous triesters is achieved via iodine catalyzed coupling of phosphites with amines, alcohols, and sulfoxime (VII), in the presence of hydrogen peroxide as oxidant.
ChemInform Abstract: Trinorditerpenes from the Roots of Flueggea virosa
Authors: Chao Chih‐Hua , Cheng Ju‐Chien , Hwang Tsong‐Long , Shen De‐Yang , Wu Tian‐Shung 
Published: April 2014

Abstractisolation and structure elucidation flueggrenes A (I) and B (II), two novel trinorditerpenes with anti‐HCV activity
ChemInform Abstract: Irigermanone, a Noriridal with Unprecedented Methylketone Function, from Iris germanica
Authors: Potterat Olivier , Herzog Carmela , Raith Melanie , Ebrahimi Samad Nejad , Hamburger Matthias 
Published: April 2014

Abstractisolation and structure determination of irigermanone (I) along with nine known congeners
ChemInform Abstract: Iron‐Catalyzed Oxidative C—H/C—H Cross‐Coupling: An Efficient Route to α‐Quaternary α‐Amino Acid Derivatives.
Authors: Li Kaizhi , Tan Guangying , Huang Jingsheng , Song Feijie , You Jingsong 
Published: April 2014

AbstractA coordination activation strategy is developed for the synthesis of α‐quaternary α‐amino acid derivatives through oxidative coupling of indoles with N‐picolinamido protected amino acid esters.
ChemInform Abstract: Protection of a New Heptapeptide from Carapax trionycis Against Carbon Tetrachloride‐Induced Acute Liver Injury in Mice.
Authors: Wang Penglong , Zhang Yuzhong , An Yawen , Xu Kuo , Xu Xin , Fu Chao , Lin Jinxuan , Xu Shixun , Li Qiang , Lei Haimin 
Published: April 2014

AbstractThe new heptapeptide GAGPHGG (OC1) (I) is isolated from Carapax trionycis.
ChemInform Abstract: Bio‐Inspired Formal Synthesis of Hirsutellones A—C Featuring an Electrophilic Cyclization Triggered by Remote Lewis Acid‐Activation.
Authors: Li Xu‐Wen , Ear Alexandre , Roger Lukas , Riache Nassima , Deville Alexandre , Nay Bastien 
Published: April 2014

AbstractA bio‐inspired strategy is used to complete the formal synthesis of the antitubercular hirsutellone B (I) and congeners A (II) and C (III), through construction of its decahydrofluorene core from a linear polyene strand activated at both ends by a silyl enol ether and an allyl acetate (not shown).
ChemInform Abstract: β‐Glucuronidase‐Responsive Prodrugs for Selective Cancer Chemotherapy: An Update
Authors: Tranoy‐Opalinski Isabelle , Legigan Thibaut , Barat Romain , Clarhaut Jonathan , Thomas Mikael , Renoux Brigitte , Papot Sebastien 
Published: April 2014

AbstractReview: 136 refs.
Prospects for engineering neurons from local neocortical cell populations as cell‐mediated therapy for neurological disorders
Authors: Bazarek Stanley , Peterson Daniel A. 
Published: April 2014

ABSTRACTThere is little cell replacement following neurological injury, limiting the regenerative response of the CNS. Progress in understanding the biology of neural stem cells has raised interest in using stem cells for replacing neurons lost to injury or to disease. Stem cell therapy may also have a role in rebuilding deficient neural circuitry underlying mood disorders, epilepsy, and pain modulation among other roles. In vitro expansion of stem cells with directed differentiation prior to transplantation is one approach to stem cell therapy. Emerging evidence suggests that it may be possible to convert in vivo endogenous neural cells to a neuronal fate directly, providing an alternative strategy for stem cell therapy to the CNS. This review assesses the evidence for engineering a subtype‐specific neuronal fate of endogenous neural cells in the cerebral cortex as a function of initial cell lineage, reactive response to injury, conversion factors, and environmental context. We conclude with a discussion of some of the challenges that must be overcome to move this alternative in vivo engineered conversion process toward becoming a viable therapeutic option. J. Comp. Neurol. 522:2857–2876, 2014. © 2014 Wiley Periodicals, Inc.
Coherent Magnetic Resonance of Nanocrystal Quantum‐Dot Luminescence as a Window to Blinking Mechanisms
Authors: van Schooten Kipp J. , Boehme Christoph , Lupton John M. 
Published: April 2014

AbstractBlinking of colloidal nanocrystal quantum dots, random intermittency in the stream of photons emitted by single particles, has long commanded the curiosity of researchers. Why does the particle suddenly shut off, and what are the pathways to quench emission? Single‐particle microscopy is not the only way to approach these fundamental questions on the interaction of light and matter: time‐domain sub‐ensemble spectroscopies can also yield relevant information on microscopic electronic processes. We illustrate recent advances in pulsed optically detected magnetic resonance and highlight the conceptual relevance to unravelling mechanisms controlling intermittency on the single‐particle level. Magnetic resonance reveals two distinct luminescence quenching channels, which appear to be related to those previously surmised from single‐particle studies: a trapped charge‐separated state in which the exciton is quenched by dissociation and the particle remains neutral; and a charged state of the particle in which spin‐dependent Auger recombination quenches luminescence.
Palladium and Gold Nanotubes as Oxygen Reduction Reaction and Alcohol Oxidation Reaction Catalysts in Base
Authors: Alia Shaun M. , Duong Kathlynne , Liu Toby , Jensen Kurt , Yan Yushan 
Published: April 2014

AbstractPalladium (PdNTs) and gold nanotubes (AuNTs) were synthesized by the galvanic displacement of silver nanowires. PdNTs and AuNTs have wall thicknesses of 6 nm, outer diameters of 60 nm, and lengths of 5–10 and 5–20 μm, respectively. Rotating disk electrode experiments showed that the PdNTs and AuNTs have higher area normalized activities for the oxygen reduction reaction (ORR) than conventional nanoparticle catalysts. The PdNTs produced an ORR area activity that was 3.4, 2.2, and 3.7 times greater than that on carbon‐supported palladium nanoparticles (Pd/C), bulk polycrystalline palladium, and carbon‐supported platinum nanoparticles (Pt/C), respectively. The AuNTs produced an ORR area activity that was 2.3, 9.0, and 2.0 times greater than that on carbon‐supported gold nanoparticles (Au/C), bulk polycrystalline gold, and Pt/C, respectively. The PdNTs also had lower onset potentials than Pd/C and Pt/C for the oxidation of methanol (0.236 V), ethanol (0.215 V), and ethylene glycol (0.251 V). In comparison to Pt/C, the PdNTs and AuNTs further demonstrated improved alcohol tolerance during the ORR.
Premating isolation is determined by larval rearing substrates in cactophilic Drosophila mojavensis. X. Age‐specific dynamics of adult epicuticular hydrocarbon expression in response to different host plants
Authors: Etges William J. , de Oliveira Cassia C. 
Published: April 2014

AbstractAnalysis of sexual selection and sexual isolation in Drosophila mojavensis and its relatives has revealed a pervasive role of rearing substrates on adult courtship behavior when flies were reared on fermenting cactus in preadult stages. Here, we assessed expression of contact pheromones comprised of epicuticular hydrocarbons (CHCs) from eclosion to 28 days of age in adults from two populations reared on fermenting tissues of two host cacti over the entire life cycle. Flies were never exposed to laboratory food and showed significant reductions in average CHC amounts consistent with CHCs of wild‐caught flies. Overall, total hydrocarbon amounts increased from eclosion to 14–18 days, well past age at sexual maturity, and then declined in older flies. Most flies did not survive past 4 weeks. Baja California and mainland populations showed significantly different age‐specific CHC profiles where Baja adults showed far less age‐specific changes in CHC expression. Adults from populations reared on the host cactus typically used in nature expressed more CHCs than on the alternate host. MANCOVA with age as the covariate for the first six CHC principal components showed extensive differences in CHC composition due to age, population, cactus, sex, and age × population, age × sex, and age × cactus interactions. Thus, understanding variation in CHC composition as adult D. mojavensis age requires information about population and host plant differences, with potential influences on patterns of mate choice, sexual selection, and sexual isolation, and ultimately how these pheromones are expressed in natural populations. Studies of drosophilid aging in the wild are badly needed.
Acid‐Catalyzed Domino Meinwald Rearrangement of Epoxides/Intramolecular [3+2] Cross‐Cycloaddition of Cyclopropane‐1,1‐dicarboxylates
Authors: Zhu Wenju , Ren Jun , Wang Zhongwen 
Published: April 2014

AbstractAn acid‐catalyzed domino Meinwald rearrangement of epoxides/intramolecular [3+2] cross‐cycloaddition of cyclopropane 1,1‐diesters was developed. This supplied a method for the construction of bridged oxa‐[n.2.1] (n = 3, 4) skeletons.
Cleavage of 2‐(Arylamino)‐4,6‐dimethoxypyrimidines To Yield Arylguanidines
Authors: Shaw Julian W. , Grayson David H. , Rozas Isabel 
Published: April 2014

AbstractA novel method for the synthesis of aryl‐substituted guanidines in good overall yields is presented; it consists of the acidic cleavage of 2‐(arylamino)‐4,6‐dimethoxypyrimidines, which were prepared by coupling aryl bromides with 2‐amino‐4,6‐dimethoxypyrimidine. This methodology introduces a new means of protection for the guanidine functionality.
Deconstructing geomorphology: an appreciation of the contributions of Barbara A. Kennedy (1943–2014)
Authors: Church Michael 
Published: April 2014

ABSTRACTBarbara Kennedy has left only a small body of work, consisting principally of eight research papers, nine commentaries and two books. Its extent belies its importance. Read systematically, the work represents a sustained and important critique of the direction taken by mainstream geomorphology since the process‐focused reorientation of the mid‐twentieth century. Copyright © 2014 John Wiley & Sons, Ltd.
Facial color processing in the face‐selective regions: An fMRI study
Authors: Nakajima Kae , Minami Tetsuto , Tanabe Hiroki C. , Sadato Norihiro , Nakauchi Shigeki 
Published: April 2014

AbstractFacial color is important information for social communication as it provides important clues to recognize a person's emotion and health condition. Our previous EEG study suggested that N170 at the left occipito‐temporal site is related to facial color processing (Nakajima et al., [2012]: Neuropsychologia 50:2499–2505). However, because of the low spatial resolution of EEG experiment, the brain region is involved in facial color processing remains controversial. In the present study, we examined the neural substrates of facial color processing using functional magnetic resonance imaging (fMRI). We measured brain activity from 25 subjects during the presentation of natural‐ and bluish‐colored face and their scrambled images. The bilateral fusiform face (FFA) area and occipital face area (OFA) were localized by the contrast of natural‐colored faces versus natural‐colored scrambled images. Moreover, region of interest (ROI) analysis showed that the left FFA was sensitive to facial color, whereas the right FFA and the right and left OFA were insensitive to facial color. In combination with our previous EEG results, these data suggest that the left FFA may play an important role in facial color processing. Hum Brain Mapp 35:4958–4964, 2014. © 2014 Wiley Periodicals, Inc.
SOCIAL INTERACTIONS AND MALARIA PREVENTIVE BEHAVIORS IN SUB‐SAHARAN AFRICA
Authors: Apouey Bénédicte , Picone Gabriel 
Published: April 2014

AbstractThis paper examines the existence of social interactions in malaria preventive behaviors in Sub‐Saharan Africa, that is, whether an individual's social environment has an influence on the individual's preventive behaviors. We focus on the two population groups which are the most vulnerable to malaria (children under 5 years and pregnant women) and on two preventive behaviors (sleeping under a bednet and taking intermittent preventive treatment during pregnancy). We define the social environment of the individual as people living in the same region. To detect social interactions, we calculate the size of the social multiplier by comparing the effects of an exogenous variable at individual and regional levels. Our data come from 92 surveys for 29 Sub‐Saharan countries between 1999 and 2012, and they cover approximately 660,000 children and 95,000 women. Our results indicate that there are social interactions in malaria preventive behaviors in the form of social multipliers effects of women's education and household wealth. The long‐run effects of these characteristics on preventive behaviors at the regional level are larger than those apparent at the individual level. Copyright © 2014 John Wiley & Sons, Ltd.