bluuebunny/crossref_metadata_2025_split huggingface dataset:
Temporal trends and predictors of salvage cancer treatment after failure following radical prostatectomy or radiation therapy: An analysis from the CaPSURE registry
Authors: Cary K. Clint , Paciorek Alan , Fuldeore Mahesh J. , Carroll Peter R. , Cooperberg Matthew R. 
Published: October 2013

BACKGROUNDProstate cancer treatment after failure of primary therapy by either radical prostatectomy or radiation therapy can vary greatly. This study sought to determine trends and predictors of salvage treatment after failure of primary treatment in a community cohort over the past 10 years.METHODSFrom the community‐based Cancer of the Prostate Strategic Urologic Research Endeavor (CaPSURE) database, 6275 patients were identified who initiated a form of primary treatment for prostate cancer; 839 of these were identified as failing treatment by biochemical recurrence or initiation of secondary treatment between 2000 and 2010. Salvage therapy was categorized as either systemic, local, or none. Patient characteristics were tested for association with salvage therapy using analysis of variance, Pearson chi‐square tests, and multinomial logistic regression analysis.RESULTSOf the 839 patients identified as failing therapy, 390 (47%), 146 (17%), and 303 (36%) received systemic, local, or no salvage therapy, respectively. Type of primary treatment received was associated with type of salvage therapy (P < .01). There has been an increasing trend in the use of local salvage therapy over the past 10 years (P = .04). Primary treatment type and biopsy Gleason score were significantly associated with type of salvage therapy.CONCLUSIONSThe use of local salvage therapy has increased over the past decade, whereas the use of systemic salvage therapy has declined. Primary treatment is an important factor in determining which type of salvage therapy a patient will receive. Cancer 2014;120:507–512. © 2013 American Cancer Society.
A six‐year experience with anal cytology in women with HPV in the lower genital tract: Utility, limitations, and clinical correlation
Authors: Cardinal L. H. , Carballo P. , Lorenzo M. C. Cabral , García A. , Suzuki V. , Tatti S. , Vighi S. , Díaz L. B. 
Published: October 2013

This study assessed the utility and limitations of anal cytology as a screening method for women infected with human papilloma virus (HPV) in the lower genital tract. Furthermore, this study aimed to establish risk factors for pathological anal cytology/biopsy findings, the prevalence of anatomopathological lesions associated with positive anal brushings, and the frequency of concomitant lesions of the lower genital tract.A cross‐sectional, retrospective, descriptive study in 207 women with HPV‐associated lesions of the lower genital tract and 25 women with immunosuppression was carried out. Anal cytology, high resolution anoscopy, and biopsy of suspicious lesions were performed.In total, 232 anal brushings were performed: 184 (79.3%) were negative, 24 (10.34%) showed atypical squamous cells of undeterminated significance, 18 (7.7%) showed low‐grade squamous intraepithelial lesions, and 6 (2.6%) showed high‐grade squamous intraepithelial lesion. Cytohistological correlation was obtained for 70 cases. The sensitivity of anal cytology in detecting intraepithelial lesions was 70%, whereas the specificity was 93%. The sensitivity of the method for detecting high‐grade lesions (84%) was higher, than that for detecting low‐grade lesions (66%). The most frequently associated pathology was vulvar lesion.It is important to perform anal brushings in women who have had lower genital tract biopsies for HPV‐associated lesions due to the high prevalence of anal lesions in such patients. Anal cytology is useful for detecting high‐grade lesions but the sensitivity for detecting low‐grade lesions is low. It is of the utmost importance to perform high‐resolution anoscopy and biopsy in women with suspicious lesions in order to confirm the pathology. Diagn. Cytopathol. 2014;42:396–400. © 2013 Wiley Periodicals, Inc.
A first‐generation microsatellite linkage map of the ruff
Authors: Farrell Lindsay L. , Burke Terry , Slate Jon , Lank David B. 
Published: October 2013

AbstractA linkage map of the ruff (Philomachus pugnax) genome was constructed based on segregation analysis of 58 microsatellite loci from 381 captive‐bred individuals spanning fourteen breeding years and comprising 64 families. Twenty‐eight of the markers were resolved into seven linkage groups and five single marker loci, homologous to known chicken (Gallus gallus) and zebra finch (Taeniopygia guttata) chromosomes. Linkage groups range from 10.1 to 488.7 cM in length and covered a total map distance of 641.6 cM, corresponding to an estimated 30–35% coverage of the ruff genome, with a mean spacing of 22.9 cM between loci. Through comparative mapping, we are able to assign linkage groups Ppu1, Ppu2, Ppu6, Ppu7, Ppu10, Ppu13, and PpuZ to chromosomes and identify several intrachromosomal rearrangements between the homologs of chicken, zebra finch, and ruff microsatellite loci. This is the first linkage map created in the ruff and is a major step toward providing genomic resources for this enigmatic species. It will provide an essential framework for mapping of phenotypically and behaviorally important loci in the ruff.
Measuring and evaluating morphological asymmetry in fish: distinct lateral dimorphism in the jaws of scale‐eating cichlids
Authors: Hata Hiroki , Yasugi Masaki , Takeuchi Yuichi , Takahashi Satoshi , Hori Michio 
Published: October 2013

AbstractThe left–right asymmetry of scale‐eatingTanganyikan cichlids is described as a unilateral topographical shift of the quadratomandibular joints. This morphological laterality has a genetic basis and has therefore been used as a model for studying negative frequency‐dependent selection and the resulting oscillation in frequencies of two genotypes, lefty and righty, in a population. This study aims were to confirm this laterality inPerissodus microlepisBoulenger andP. straeleni(Poll) and evaluate an appropriate method for measuring and testing the asymmetry. Left–right differences in the height of the mandible posterior ends (HMPE) and the angle between the neurocranium and vertebrae ofP. microlepisandP. straeleniwere measured on skeletal specimens. Snout‐bending angle was also measured using a dorsal image of the same individuals following a previous method. To define which distribution model, fluctuating asymmetry (FA), directional asymmetry (DA), or antisymmetry (AS), best fit to the lateral asymmetry of the traits, we provided an R package,IASD. As a result,HMPEand neurocranium–vertebrae angle of both species were best fitted toAS, suggesting thatP. microlepisandP. straelenishowed a distinct dimorphism in these traits, although snout‐bending angle ofP. microlepiswas best fitted toFA. Measurement error was low forHMPEcomparing the snout‐bending angle inP. microlepis, indicating that measuringHMPEis a more accurate method. The scale‐eating tribe Perissodini showed distinct antisymmetry in the jaw skeleton and neurocranium–vertebrae angle, and this laterality remains a valid marker for further evolutionary studies.
Chemistry and Biology of the Polycyclic Polyprenylated Acylphloroglucinol Hyperforin
Authors: Richard Jean‐Alexandre 
Published: October 2013

Abstract(+)‐Hyperforin (1) is a polyprenylated acylphloroglucinol (PPAP) natural product isolated in 1971 from Hypericum perforatum. Also known as St. John's wort, Hypericum perforatum is a popular medicinal plant because of its antidepressant properties. (+)‐Hyperforin (1) is the main component of the plant and has attracted the interest of the scientific community since it was identified as the agent responsible for the antidepressant activity. The subsequent discovery that it also displayed a wide range of biological activities triggered the interest of synthetic chemists because of its appealing, compact molecular structure. This microreview presents an overview of the synthetic studies reported so far for the racemic and enantioselective syntheses of (+)‐hyperforin (1) and analogues, and attempts to shed light on the intriguing structure–activity relationships (SARs) of the natural product.
Case of partial vertical laryngectomy with vocal cord reconstruction using a thyroid gland flap
Authors: Ikeda Atsuhiko , Okamoto Hiroki , Tsuchiya Yoshimasa , Nishimura Kunihiro , Ueda Hiromi , Ogawa Tetsuya 
Published: October 2013

ABSTRACTBackgroundTo preserve laryngeal function in early‐stage laryngeal cancer, chemotherapy and radiotherapy are performed more often than surgery as initial treatment. However, in recurrent cases, complex salvage surgery is often required as patients who received aggressive chemoradiotherapy are susceptible to postoperative complications. We report here salvage therapy that preserved laryngeal function in a recurrent case.MethodsA 52‐year‐old man with recurrent laryngeal cancer (rT2N0M0) after chemoradiotherapy and followed by induction chemotherapy underwent partial vertical laryngectomy and right vocal cord reconstruction with a thyroid flap.ResultsLaryngeal functions were successfully preserved and the patient was discharged 2 months after surgery.ConclusionThe number of salvage surgeries performed after high‐dose chemotherapy and radiation is expected to increase in the future. A thyroid gland flap promises to be an effective treatment option for vocal cord reconstruction especially for patients at high risk of postchemoradiotherapy complications. © 2014 Wiley Periodicals, Inc. Head Neck 36: E73–E77, 2014
Deconstructing Global Markets Through Critical Performative Experiences in Puerto Rico
Authors: Medina Carmen Liliana , Weltsek Gustave J. 
Published: October 2013

AbstractCritical Performative Pedagogies, the idea that “The nature of drama as a once removed creative experience turns non‐critical implicit classroom identity formation into explicit identity performance as it asks participants to actively reflect upon how identity is created and engaged within fictional social interactions.” (Weltsek and Medina, 2007) is used to explore English language learning as a political act. Using critical ethnographic research conducted with and on two different groups of students in Puerto Rico, one elementary and one University, as their launching point Gustave Weltsek and Carmen Lillian Medina struggle with the ways in which personal, community and institutionalized literacy education is negotiated within colonial spaces. IN this Water Cooler chat they explain that “When students see themselves as actively involved in the creation/performance of any communicative event, especially one situated as ‘educational’, aware of how they construct their actions the opportunity exists for them to take a more conscious ownership of their education. When applied to literacy learning ‘literacy’ becomes the way multiple sign systems are used to outwardly perform emergent identities. Drama then become an ideal way to observe and articulate how personal, community and institutional literacies are negotiated and created within the performance of self. It is this observation and articulation which ultimately empowers and drives student learning.”
Xpert MTB/RIF for diagnosis of tuberculous cervical lymphadenitis in HIV‐infected patients
Authors: Ablanedo‐Terrazas Yuria , Alvarado‐de la Barrera Claudia , Hernández‐Juan Ramón , Ruiz‐Cruz Matilde , Reyes‐Terán Gustavo 
Published: October 2013

Objectives/HypothesisThe World Health Organization endorsed the Xpert MTB/RIF assay for the diagnosis of pulmonary tuberculosis (TB), but there is limited information about the utility of this assay for the diagnosis of TB lymphadenitis. Therefore, the objective of this study was to assess the diagnostic accuracy of Xpert MTB/RIF assay in HIV‐infected patients with palpable cervical lymph nodes.Study DesignProspective, diagnostic test study.MethodsConsecutive patients with cervical lymphadenopathy were prospectively enrolled between January 2011 and March 2013. Lymph node specimens were obtained through fine‐needle aspiration or excisional biopsy. Mycobacterial culture was considered as the gold standard.ResultsMycobacterium TB was cultured from 15 of 68 specimens (22.05%), and 53 specimens had negative cultures (77.94%). The sensitivity of Xpert MTB/RIF was 100% (95% CI, 74.65%–100%), and the specificity was 100% (95% CI, 91.58%–100%). Smear microscopy had a lower diagnostic performance.ConclusionAlthough based on a limited sample size, our study indicates that Xpert MTB/RIF is a useful method for the diagnosis of cervical TB lymphadenitis in HIV‐infected patients, regardless of the bacillary load in smear‐positive samples or the CD4 T cell count. The sensitivity, specificity, positive predictive value, and negative predictive value were similar to gold‐standard culture.Level of EvidenceN/A. Laryngoscope, 124:1382–1385, 2014
My Anger Is Your Gain, My Contempt Your Loss: Explaining Consumer Responses to Corporate Wrongdoing
Authors: Romani Simona , Grappi Silvia , Bagozzi Richard P. 
Published: October 2013

ABSTRACTTwo forms of consumer response to corporate wrongdoing are constructive punitive actions (i.e., those designed to induce firms to change their behavior but with the hope of sustaining relationships with consumers) and destructive punitive actions (i.e., those intended to discredit or harm firms, ultimately leading to disengagement from firms). This study investigates the conditions under which one or the other actions are taken and shows that anger regulates the former, whereas contempt governs the latter. Hypotheses are tested in two studies: a laboratory experiment and a naturalistic field study with an actual instance of recent corporate malfeasance. Theoretical and managerial implications are discussed.
Option Framing and Product Feature Recommendations: Product Configuration and Choice
Authors: Herrmann Andreas , Hildebrand Christian , Sprott David E. , Spangenberg Eric R. 
Published: October 2013

ABSTRACTWhen configuring a customized product, consumers must decide which product features to include. While many times firms allow consumers to add features to a base item (hereinafter referred to as additive option framing), it is also possible in some settings to remove undesired features from a fully equipped product (subtractive option framing). At the same time, companies not only provide different option‐framing formats, but also include recommendations from different sources such as what other customers have chosen previously or what is recommended by the company. This research provides evidence from two field experiments using a German car manufacturer's online configurator that customer recommendations in an additive option‐framing format affect customer spending equally well as subtractive option framing. A follow‐up experiment reveals that customer recommendations lead to increased positive thoughts about the recommended option, which stimulates consumers’ intention to buy the final product.
More than Just an Opinion: The Effect of Verbal Self‐Expression on Consumer Choice
Authors: Kokkoris Michail D. , Kühnen Ulrich 
Published: October 2013

ABSTRACTIn an ever‐widening range of occasions, consumers have the opportunity to comment and express their opinions on brands and products. However, little is known about how voicing opinions about the choice options before actually choosing might affect consumer choice, and specifically liking of choice. This paper proposes that pre‐choice opinion expression undermines the effect of post‐choice bolstering, because opinion sufficiently satisfies self‐expressive needs and therefore supersedes the use of subsequent choice as a self‐expressive resource. This proposition is based on the assumption that opinion can psychologically substitute for choice, because the two represent alternative routes to self‐expression. Two experiments provide empirical support for this hypothesis. Study 1 showed that after articulating their opinions about the choice options, participants were less likely to idealize their choices, and this effect was mediated by a change in the construal of choice as self‐expression. Study 2 further showed that this effect is moderated by public versus private occasions of opinion voicing and by individual differences in the value of expression. Together, findings support that opinion is enough to express the self, and if such an opportunity is made available prior to choosing, consumers’ liking of their choices is weakened.
Time‐Resolved Angiography using InfLow Subtraction (TRAILS)
Authors: Kopeinigg Daniel , Bammer Roland 
Published: October 2013

PurposeA novel pseudo‐continuous arterial spin labeling based angiographic method called Time‐Resolved Angiography using InfLow Subtraction is introduced and used to acquire time‐resolved whole‐head angiographic data sets in healthy volunteers in a clinical feasible scan time of less than 5 min.MethodsUsing this new method, in conjunction with a sliding window reconstruction, a temporal resolution of 7.2 ms with a low temporal footprint of 432 ms can be achieved.ResultsExcellent vessel delineation compared to a time‐of‐flight MRA was demonstrated. Normal variations of the vascular system including the Circle of Willis (CoW) were identified using Time‐Resolved Angiography Using Inflow Subtraction. Signal intensities were measured in various vascular segments to quantify the blood transit time.ConclusionIn this feasibility study, we showed that Time‐Resolved Angiography using InfLow Subtraction can be used to acquire hemodynamic information of the whole head in healthy volunteers with a high temporal and spatial resolution. Further studies in patients that suffer from vascular diseases to explore various flow patterns including longer transit time are needed. Magn Reson Med 72:669–678, 2014. © 2013 Wiley Periodicals, Inc.
CCSS‐ELA
Authors: Valencia Sheila W. , Wixson Karen K. 
Published: October 2013

AbstractThe purpose of this article is to provide guidance on the implementation of the Common Core State Standards for English language arts (CCSS‐ELA). Toward this end, suggestions and cautions are provided that focus on understanding the vision, understanding the anchor and grade‐level standards, and understanding the implications for instruction. In general, this article stresses the importance of attending to the various “parts” of the standards within the context of the larger vision as a means of avoiding missteps in implementation.
Shape‐stabilized Bi2Te3‐capped Tellurium Nanorods
Authors: Dong Hailong , Popescu Radian , Gerthsen Dagmar , Feldmann Claus 
Published: October 2013

AbstractTellurium nanorods with a diameter of 10–20 nm and a length of 30–60 nm are prepared via hydrazine‐driven reduction of telluric acid. The size of the nanorods is controlled by the experimental conditions, including the N2H4·H2O–to–H2TeO4·2H2O ratio and the addition of polyvinylpyrrolidone (PVP). Although obtained at 0 °C, the as‐prepared tellurium nanorods are readily crystalline. For low aspect ratios (<5), the colloid and shape stability of the nanoparticles turned out as low; they show rapid agglomeration and merging due to storage and/or due to gentle heating (e.g., stirring, centrifugation). To increase the colloid and shape stability, a thin capping of Bi2Te3 is therefore established after the synthesis by addition of Bi(C6H5)3. As a result, Te@Bi2Te3 core@shell nanorods are obtained, exhibiting a Bi2Te3 capping layer of 6 nm in thickness. Composition and structure are validated by low‐energy STEM, HRTEM, HAADF‐STEM, XRD, FT‐IR, and line‐scan EDXS. The shape‐stabilized Bi2Te3‐capped tellurium nanorods can become an interesting precursor for Bi‐Te‐based thin‐film solar cells, thermoelectrics, or topological insulators.
There's Glory for You!
Authors: Ketland Jeffrey 
Published: October 2013

AbstractThis dialogue concerns metasemantics and language cognition. It defends a Lewisian conception of languages as abstract entities (Lewis 1975), arguing that semantic facts are necessities (Soames 1984), and therefore not naturalistically reducible. It identifies spoken languages as idiolects, in line roughly with Chomskyan I-languages. It relocates traditional metasemantic indeterminacy arguments as indeterminacies of what language an agent speaks or cognizes. Finally, it aims to provide a theoretical analysis of the cognizing relation in terms of the agent's assigning certain meanings to strings.
THE CONFESSIONAL UNMASKED: RELIGIOUS MERCHANDISE AND OBSCENITY IN VICTORIAN ENGLAND
Authors: Janes Dominic 
Published: October 2013

On 19 May 1868 the ConservativeMP Percy Wyndham rose in the House of Commons to ask the Secretary of State for the Home Department “whether he is aware that Publications, the sale of which has been condemned by a Court of Law, are now being openly offered for sale in the Streets of London, and such being the case, whether the Police have power to interfere?” Gathorne Hardy replied thatSir, I have made inquiries into the subject of my hon. Friend's Question, and I find that since the decision referred to that book has not been sold in the streets, though there is no doubt – for I hold one of the covers in my hand – that the cover is put on books in order to sell them, but within the cover the purchaser finds a book of a totally different character, and of a harmless nature. The attraction of the title appears to be great, as it is used for advertising and selling books of a very different kind. I am told that the Police keep a register of the books and pamphlets sold in the streets, and interfere when their interference is called for. As to the book referred to by my hon. Friend – for I presume his Question relates toThe Confessional Unmasked– I find on inquiry at the depôt from which it was issued that all the remaining copies have been destroyed, and that there are none now for sale. (Hansard)The legal regulation of pornography in England from the later nineteenth century relied on a definition of obscenity derived from a case concerning a religious tract,The Confessional Unmasked(1836) (McDonald). This pamphlet had been circulating for many years before it came to the notice of the courts. Henry Scott, a metal broker from Wolverhampton, had reprinted the text and circulated it on behalf of the Protestant Evangelical Union. The case went on appeal from the local magistrates, one of whom was Benjamin Hicklin, to the Court of Queen's Bench, where judgment was given on 29 April 1868 (“A Judgment” and Scott). This seems, on the face of it, bizarre. Indeed, that this case was brought at all has been seen as highlighting the problematic nature of the Obscene Publications Act (1857) under which the action was brought (Roberts 627). However, it can be argued that the danger that the act was defined to prevent had much more to do with the publication of religious tracts than might appear to have been the case.