bluuebunny/crossref_metadata_2025_split huggingface dataset:
A whole genome analyses of genetic variants in two Kelantan Malay individuals
Authors: Wan Juhari Wan Khairunnisa , Md Tamrin Nur Aida , Mat Daud Mohd Hanif Ridzuan , Isa Hatin Wan , Mohd Nasir Nurfazreen , Maran Sathiya , Abdul Rajab Nur Shafawati , Ahmad Amin Noordin Khairul Bariah , Nik Hassan Nik Norliza , Tearle Rick , Razali Rozaimi , Merican Amir Feisal , Zilfalil Bin Alwi 
Published: October 2014

AbstractBackgroundThe sequencing of two members of the Royal Kelantan Malay family genomes will provide insights on the Kelantan Malay whole genome sequences. The two Kelantan Malay genomes were analyzed for the SNP markers associated with thalassemia andHelicobacter pyloriinfection.Helicobacter pyloriinfection was reported to be low prevalence in the north-east as compared to the west coast of the Peninsular Malaysia and beta-thalassemia was known to be one of the most common inherited and genetic disorder in Malaysia.ResultBy combining SNP information from literatures, GWAS study and NCBI ClinVar, 18 unique SNPs were selected for further analysis. From these 18 SNPs, 10 SNPs came from previous study ofHelicobacter pyloriinfection among Malay patients, 6 SNPs were from NCBI ClinVar and 2 SNPs from GWAS studies. The analysis reveals that both Royal Kelantan Malay genomes shared all the 10 SNPs identified by Maran (Single Nucleotide Polymorphims (SNPs) genotypic profiling of Malay patients with and without Helicobacter pylori infection in Kelantan, 2011) and one SNP from GWAS study. In addition, the analysis also reveals that both Royal Kelantan Malay genomes shared 3 SNP markers; HBG1 (rs1061234), HBB (rs1609812) and BCL11A (rs766432) where all three markers were associated with beta-thalassemia.ConclusionsOur findings suggest that the Royal Kelantan Malays carry the SNPs which are associated with protection toHelicobacter pyloriinfection. In addition they also carry SNPs which are associated with beta-thalassemia. These findings are in line with the findings by other researchers who conducted studies on thalassemia andHelicobacter pyloriinfection in the non-royal Malay population.
Sparse coding of the modulation spectrum for noise-robust automatic speech recognition
Authors: Ahmadi Sara , Ahadi Seyed Mohammad , Cranen Bert , Boves Lou 
Published: October 2014

AbstractThe full modulation spectrum is a high-dimensional representation of one-dimensional audio signals. Most previous research in automatic speech recognition converted this very rich representation into the equivalent of a sequence of short-time power spectra, mainly to simplify the computation of the posterior probability that a frame of an unknown speech signal is related to a specific state. In this paper we use the raw output of a modulation spectrum analyser in combination with sparse coding as a means for obtaining state posterior probabilities. The modulation spectrum analyser uses 15 gammatone filters. The Hilbert envelope of the output of these filters is then processed by nine modulation frequency filters, with bandwidths up to 16 Hz. Experiments using the AURORA-2 task show that the novel approach is promising. We found that the representation of medium-term dynamics in the modulation spectrum analyser must be improved. We also found that we should move towards sparse classification, by modifying the cost function in sparse coding such that the class(es) represented by the exemplars weigh in, in addition to the accuracy with which unknown observations are reconstructed. This creates two challenges: (1) developing a method for dictionary learning that takes the class occupancy of exemplars into account and (2) developing a method for learning a mapping from exemplar activations to state posterior probabilities that keeps the generalization to unseen conditions that is one of the strongest advantages of sparse coding.
Reducing avoidable pressure ulcers: an online clinical ordering system
Authors: Acton Claire 
Published: October 2014

Healthcare practitioners face diverse challenges presented by an ageing population, reducing funds, public demand for better health care, and a zero tolerance to avoidable healthcare-acquired injuries, such as pressure ulcers. To support the reduction in avoidable pressure ulcers European Pressure Ulcer Advisory Panel and National Institute for Health and Clinical Excellence guidelines recommend patient repositioning, the provision of either an active or reactive pressure-redistributing support surface and, for some, complete and permanent off-loading of the tissue. Guys and St Thomas's NHS Foundation Trust recognised that an evidence-based prevention strategy was required to reduce the incidence of pressure ulcers in line with the Harm Free Care initiative. As part of the prevention strategy, eTRACE was implemented, an online clinical ordering system that uses the patients' clinical risk assessment in conjunction with the Trust's clinical protocols to recommend appropriate equipment selection. Additionally the system supports the organisational and national reporting/management requirements. This article will review the clinical and economic evidence to support the introduction of eTRACE and how this system has contributed to the Trust's agenda in reducing avoidable pressure ulcers.
The delivery of recreation programs: Students gain entry level management skills through service learning
Authors: Zimmermann Jo An M , Dupree Jessica , Hodges Jan S 
Published: October 2014

Service learning is a well-established pedagogy within higher education. Specifically, service learning allows students to engage in 'real world' activitites to practice skills and reflect upon their own competence. To enhance the effectiveness of service learning, instructors need to consider a multitude of learning influences. This study adhered to the tenants of the Social Cognitive Theory (Bandura, 1986; Schunk, 2004) to engage students in service learning activities related to entry level administrative competencies. Data analysis included a content analysis of reflection papers to determine how many times competencies expected of entry level recreation professionals were mentioned. Students percieved the acquisition of competencies consistent with entry level competencies identified within the recreation industry. Results contribute to the development of effective assignments to facilitate the acquisition of desired professional competencies.
Alliances and Contestations in the Legal Production of Space: The Case of Bali
Authors: Wardana Agung 
Published: October 2014

AbstractThe controversy over the provincial spatial planning regulation for Bali Province reflects the dynamic of Balinese society in the era of regional autonomy. The dynamic is polarised between expanding the tourism and real estate industry for economic reasons and constraining such expansion for the sake of protecting Bali’s environment and culture. Thus, the law governing space becomes an essential means to intervene in crafting the relations between competing interests over space. The application of the law itself is also complicated by the condition of legal pluralism which provides different and sometimes conflicting sources of legality to be used to justify the interests of legal actors. This article aims at highlighting how space is produced in a pluralistic legal setting and examining whose interests are served by the condition of legal pluralism in contemporary Bali. Employing socio-legal methods with Lefebvre’s conception of space and legal pluralism as an integrating analytical framework, the article contributes to the literature on spatial planning law in Indonesia that is dominated by “legal centralism” and a given notion of space.
Preparation of water-dispersive poly(3,4-ethylenedioxythiophene) (PEDOT) conductive nanoparticles in lignosulfonic acid solution
Authors: Deng Yonghong , Li Zhuoxi , Qiu Xueqing , Zhao Dacheng 
Published: October 2014

AbstractLignosulfonic acid (LS) has been applied both as dispersant and dopant for chemical polymerization of 3,4-ethylenedioxythiophene (EDOT). EDOT is successfully polymerized in LS aqueous solutions, resulting in a water-dispersive poly(3,4-ethylenedioxythiophene) (PEDOT) conductive nanoparticle (PEDOT:LS). The structure, intermolecular interaction, and performance of the PEDOT:LS were investigated by ultraviolet-visible-Near-infrared spectrophotometry, Fourier transform infrared spectroscopy, thermogravimetric analysis, dynamic light scattering, transmission electron microscopy, X-ray photoelectron spectroscopy, and surface resistivity tester. Results were interpreted in a way that PEDOT:LS is a polyelectrolyte complex, in which the highly hydrophobic PEDOT is in the inner part of the particle and the LS-rich layer with high hydrophilicity is on its surface. During oxidizing reaction of EDOT to PEDOT in LS, the water-insoluble PEDOT product is adsorbed on the surface of water-soluble LS by electrostatic attraction and forms PEDOT:LS polyelectrolyte complexes. In this process, excess LS is needed to be adsorbed on the surface of PEDOT:LS complexes. The process is driven by π-π interaction to increase the water solubility and contributes to a continuous polymerization. The PEDOT:LS as coating has a good conductivity, transparency, humidity resistance, water resistance, and thermal stability and can be used as high-performance antistatic agents.
Covariate adjusted differential variability analysis of DNA methylation with propensity score method
Authors: Kuan Pei Fen 
Published: October 2014

AbstractIt has been proposed recently that differentially variable CpG methylation (DVC) may contribute to transcriptional aberrations in human diseases. In large scale epigenetic studies, potential confounders could affect the observed methylation variabilities and need to be accounted for. In this paper, we develop a robust statistical model for differential variability DVC analysis that accounts for potential confounding covariates by utilizing the propensity score method. Our method is based on a weighted score test on strata generated propensity score stratification. To the best of our knowledge, this is the first proposed statistical method for detecting DVCs that adjusts for confounding covariates. We show that this method is robust against model misspecification and achieves good operating characteristics based on extensive simulations and a case study.
Estimating point and density forecasts for the US economy with a factor-augmented vector autoregressive DSGE model
Authors: Bekiros Stelios , Paccagnini Alessia 
Published: October 2014

AbstractAlthough policymakers and practitioners are particularly interested in dynamic stochastic general equilibrium (DSGE) models, these are typically too stylized to be applied directly to the data and often yield weak prediction results. Very recently, hybrid DSGE models have become popular for dealing with some of the model misspecifications. Major advances in estimation methodology could allow these models to outperform well-known time series models and effectively deal with more complex real-world problems as richer sources of data become available. In this study we introduce a Bayesian approach to estimate a novel factor augmented DSGE model that extends the model of Consolo et al. [Consolo, A., Favero, C.A., and Paccagnini, A., 2009. On the Statistical Identification of DSGE Models. Journal of Econometrics, 150, 99–115]. We perform a comparative predictive evaluation of point and density forecasts for many different specifications of estimated DSGE models and various classes of VAR models, using datasets from the US economy including real-time data. Simple and hybrid DSGE models are implemented, such as DSGE-VAR and tested against standard, Bayesian and factor augmented VARs. The results can be useful for macro-forecasting and monetary policy analysis.
Evidence for Stabilizing Selection on Codon Usage in Chromosomal Rearrangements ofDrosophila pseudoobscura
Authors: Fuller Zachary L , Haynes Gwilym D , Zhu Dianhui , Batterton Matthew , Chao Hsu , Dugan Shannon , Javaid Mehwish , Jayaseelan Joy C , Lee Sandra , Li Mingmei , Ongeri Fiona , Qi Sulan , Han Yi , Doddapaneni Harshavardhan , Richards Stephen , Schaeffer Stephen W 
Published: October 2014

AbstractThere has been a renewed interest in investigating the role of stabilizing selection acting on genome-wide traits such as codon usage bias. Codon bias, when synonymous codons are used at unequal frequencies, occurs in a wide variety of taxa. Standard evolutionary models explain the maintenance of codon bias through a balance of genetic drift, mutation and weak purifying selection. The efficacy of selection is expected to be reduced in regions of suppressed recombination. Contrary to observations in Drosophila melanogaster, some recent studies have failed to detect a relationship between the recombination rate, intensity of selection acting at synonymous sites, and the magnitude of codon bias as predicted under these standard models. Here, we examined codon bias in 2798 protein coding loci on the third chromosome of D. pseudoobscura using whole-genome sequences of 47 individuals, representing five common third chromosome gene arrangements. Fine-scale recombination maps were constructed using more than 1 million segregating sites. As expected, recombination was demonstrated to be significantly suppressed between chromosome arrangements, allowing for a direct examination of the relationship between recombination, selection, and codon bias. As with other Drosophila species, we observe a strong mutational bias away from the most frequently used codons. We find the rate of synonymous and nonsynonymous polymorphism is variable between different amino acids. However, we do not observe a reduction in codon bias or the strength of selection in regions of suppressed recombination as expected. Instead, we find that the interaction between weak stabilizing selection and mutational bias likely plays a role in shaping the composition of synonymous codons across the third chromosome in D. pseudoobscura.
Serge Lifar as a Dance Historian and the Myth of Russian Dance in Zarubezhnaia Rossiia (Russia Abroad) 1930–1940
Authors: Veroli Patrizia 
Published: October 2014

Serge Lifar built his career during the 1930s, a decade crucial to understanding his ‘années noires’ – or ‘black years’, as the French historian Henry Rousso called the period of the German occupation of Paris (1940–1944). Lifar's powerful and respected position at the Paris Opéra, the social connections he had built and maintained and the psychological impact of exile: all these elements help clarify Lifar's accommodating attitude towards the German occupants of his adopted city. 1 During the 1930s Lifar came to be accepted in French intellectual society as the ‘heir’ of Serge Diaghilev. Through his publications he made a powerful contribution to the process by which Diaghilev's Ballets Russes assumed its paramount position in the development of modern ballet, a process set in motion by the impresario himself. 2 Lifar played this role chiefly in France. In the English-speaking world, where relatively few of his books appeared in translation, other writers served to canonise the Diaghilev endeavour, albeit for somewhat different ends. 3 A list of Lifar's publications in Russian and other languages (French above all) displays the growing influence of his actions and authority, the power of his connections (inherited primarily from Diaghilev), and his relentless will to overcome the problems of emigration as he secured not only success as a dancer and choreographer but also a public reputation as an intellectual. 4 The recent discovery of new evidence has led to the identification of the respected Pushkin authority Modeste Hofmann 5 as the writer whose unacknowledged work enabled Lifar to establish himself as an historian. This evidence, provided by Hofmann's grandsons André and Vladimir Hofmann, raises serious questions about the authority of Lifar's books. An interplay of subjective relationships is woven into the texture of these narratives in which survival and ambition, a paternal attitude and filial respect, exist in constant tension. Neither the making of these books nor the myth of Russian dance which they espouse can be understood without placing their authors in the milieu they shared in Paris as Russian émigrés.
Medullary cavity diameter of metacarpal and metatarsal bones in cats
Authors: Amort K. , Failing K. , Kramer M. , Kornmayer M. 
Published: October 2014

SummaryObjectives: To compare radiography and computed tomography (CT) for the evaluation of medullary cavity diameters of metacarpal and metatarsal bones in cats and to analyse their correlation with intramedullary pin size.Methods: Radiography and CT were performed in cadavers (n = 12). The mid-diaphysis was determined and the medullary cavity diameter was measured by two observers. Each bone was osteotomized at the mid-diaphysis, Kirschner wires were inserted, and pin size was documented. Intra- and interobserver variability was evaluated (hierarchical analysis of variance). Radiography and CT were compared (correlation analysis, a t-test for dependent samples, a Bland-Altman analysis) and pin size, radiography and CT were compared (regression and correlation analysis).Results: Intra-observer variability was low for radiographs and CT, with an estimated median variation of 0.10 mm for radiographs and 0.12 mm for CT. Inter-observer variability was low, with a median variation of 0.03 mm for radiographs and 0.21 mm for CT. There was a high correlation between radiography and CT for the assessment of the medullary cavity diameter. A high correlation was found between pin size and measurement on radiographs, and between pin size and measurements on CT. In two cats, pin insertion was difficult or impossible.Clinical significance: Mid-diaphyseal measurements are applicable methods for the assessment of the medullary cavity diameter in feline metacarpal and metatarsal bones regarding intramedullary pins. In some cats the medullary cavity diameter may be too small for intramedullary pinning techniques, which can be identified preoperatively on radiographs.
Barbed versus smooth poly- propylene three-loop pulley sutures for repair of canine gastrocnemius tendon
Authors: Harper T. A. , Mitchell M. A. , McFadden M. S. , Perry B. Heggem , Perry B. S. 
Published: October 2014

SummaryObjective: To compare the ultimate tensile strength (UTS) and load to 1 and 3 mm gap formation of smooth (3-metric) and knotless barbed (4-metric) polypropylene sutures placed in a three-loop pulley pattern for canine gastrocnemius tendon repair.Study design: In vitro.Sample size: Thirty-three paired bonetendon units with one of each pair assigned to each suture type. Barbed suture size was based on previously published materials testing results.Methods: Each unit was placed in a servohydraulic testing machine and tested under single cycle tensile loading until repair failure.Results: There was a significantly higher UTS for smooth polypropylene compared to the barbed polypropylene repairs. The loads resulting in 1 and 3 mm gaps for the barbed repairs were consistently significantly less than the corresponding smooth polypropylene repair values.Conclusion: The knotted smooth polypropylene repair was consistently stronger than the knotless barbed polypropylene repair when placed in a three-loop pulley pattern for gastrocnemius repair.Clinical significance: Knotless barbed polypropylene suture should not be considered equivalent to knotted smooth polypropylene of comparable tensile strength when placed in a three-loop pulley pattern for canine gastrocnemius tendon repair. The low failure loads of the barbed repair are probably due to failure of the barbs to anchor consistently throughout the tendon in the knotless configuration.
Des mots, de leurs histoires et de quelques enjeux
Authors: Gisel Pierre 
Published: October 2014

Pour comprendre la multiplicité des appellations en usage à propos de l’étude scientifique du « religieux », l’auteur analyse l’histoire de cette terminologie mouvante. Il examine d’abord celle qui vise à définir une discipline appelée tour à tour « Sciences religieuses », « sciences des religions », « religiologie », « Religious Studies », puis celle des formulations visant à caractériser une histoire religieuse et montre qu’il existe une hésitation symétrique pour la philosophie qui oscille entre « philosophie religieuse » ou « philosophie de la religion ». Il y voit le signe d’une tâche jamais achevée pour définir ce qu’on entend par « religion », « croyance », « science » ou « philosophie ».
Confession, confessionnalisation
Authors: Duhamelle Christophe 
Published: October 2014

D’abord circonscrit au monde germanique et au milieu des historiens de la Réforme, le débat autour de la confessionnalisation a obligé à reconsidérer le processus religieux qui est enclenché au xvi e s.. La paix d’Augsbourg en 1555, confortée par la paix de Westphalie en 1648, a pour conséquence d’inscrire dans la durée une distinction confessionnelle qui lie étroitement politique, droit et religion. Ainsi la Réforme n’est plus interprétée seulement comme un moment clé de la sécularisation. Le « confessionnel » est le domaine où se construit le rapport entre appartenance politique, appartenance religieuse et appartenance sociale. Et ce rapport n’est pas une simple intersection : il est un problème posé en termes nouveaux. La « confession » est une des réponses apportées à la construction de l’État moderne, celle qui légalise la diversité en déterminant quels pouvoirs ont le droit de choisir et quels textes ils peuvent adopter, entraînant à la fois une disqualification des autres options et une cristallisation des confessions légitimes.
Le « tournant culturel » de l'histoire « religieuse » et « ecclésiastique »
Authors: Grosse Christian 
Published: October 2014

La contribution s’attache à décrire le mouvement qui, sur un gros siècle, entre la fin du xix e et le début du xxi e siècle, conduit une tradition historiographique qui s’est d’abord définie comme « ecclésiastique » à accomplir un « tournant » épistémologique qui l’amène à se définir plutôt comme « culturelle ». Tout en éclairant les courants qui, jouant un rôle de médiation, ont contribué à rendre cette évolution possible, l’auteur bat en brèche l’idée que nous sommes véritablement en présence d’un « tournant », et suggère que cette approche renoue en réalité avec de plus anciennes traditions. On serait ainsi moins strictement en présence d’une forme de rupture que de la récupération d’une perspective qui s’est trouvée marginalisée au moment même où l’historiographie entamait l’évolution dont il est question ici. Le mouvement d’ensemble est étudié en portant une attention plus forte aux manières dont s’est écrite l’histoire des christianismes, en particulier durant l’époque moderne.