bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of dietary macronutrients on postprandial incretin hormone release and satiety in obese and normal-weight women
Authors: Wikarek Tomasz , Chudek Jerzy , Owczarek Aleksander , Olszanecka-Glinianowicz Magdalena 
Published: August 2013

The aim of the present study was to assess the effect of dietary macronutrients on postprandial incretin responses and satiety and hunger sensation in obese and normal-weight women. A total of eleven obese and nine normal-weight women were recruited for the assessment of plasma concentrations of glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP) and insulin and the sensation of satiety and hunger using a visual analogue scale before and during a 6 h period after administration of three different macronutrient test meals. The AUCtotalGLP-1 and AUCtotalGIP values were decreased in obese women after the consumption of a fatty meal and all the test meals, respectively. However, the AUCtotal insulin value after a carbohydrate meal was greater in the obese group. The AUCtotal satiety value was decreased only after the intake of the protein meal in obese women when compared with normal-weight women. After the consumption of the fatty meal, a significant positive correlation between maximum satiety sensation and the AUCtotal GLP-1 value in the obese group and that between minimum hunger sensation and the AUCtotal GLP-1 value in the normal-weight group were observed. In conclusion, the findings of the present study suggest that: (1) satiety sensation after consumption of carbohydrate and protein meals in the obese group is related to the postprandial insulin response, while after consumption of a fatty meal, it is related to the postprandial GLP-1 release; (2) the postprandial GIP response does not influence the sensation of satiety and hunger; (3) the reduced GLP-1 release after the intake of a fatty meal in obese individuals may explain impaired satiety sensation; (4) the impaired postprandial GIP response is not related to the consumption of macronutrients and may be the early indicator of incretin axis dysfunction in obese women.
Methionine improves the performance and breast muscle growth of broilers with lower hatching weight by altering the expression of genes associated with the insulin-like growth factor-I signalling pathway
Authors: Wen Chao , Wu Ping , Chen Yueping , Wang Tian , Zhou Yanmin 
Published: August 2013

The present study aimed to investigate the responses of broilers with different hatching weights (HW) to dietary methionine (Met). A total of 192 1-d-old Arbor Acres broiler chicks with different HW (heavy: 48·3 (sem 0·1) g and light: 41·7 (sem 0·1) g) were allocated to a 2 (HW) × 2 (Met) factorial arrangement with six replicates of eight chicks. Control starter (1–21 d) and finisher (22–42 d) diets contained 0·50 and 0·43 % Met, respectively. Corresponding values for a high-Met treatment were 0·60 and 0·53 %. Light chicks had poorer (P< 0·05) growth performance and breast muscle weight and lower (P< 0·05) insulin-like growth factor-I (IGF-I) concentration and mRNA level in breast muscle than heavy chicks when both were fed the control diets. High-Met diets improved performance and promoted breast muscle growth and IGF-I concentration in light chicks (P< 0·05). Increased IGF-I and target of rapamycin (TOR) mRNA levels as well as decreased eIF4E-binding protein 1 (4EBP1), atrogin-1 and forkhead box O 4 (FOXO4) mRNA levels were induced by high-Met diets in light chicks (P< 0·05). In conclusion, the Met requirement of broilers might depend on their HW and Met levels used in the control diets in the present study were adequate for heavy chicks but inadequate for light chicks, resulting in poorer performance and breast muscle growth, which were improved by increasing dietary Met supply presumably through alterations in IGF-I synthesis and gene expression of the TOR/4EBP1 and FOXO4/atrogin-1 pathway.
Effects of bovine lactoferrin on the immature porcine intestine
Authors: Nguyen Duc Ninh , Li Yanqi , Sangild Per T. , Bering Stine B. , Chatterton Dereck E. W. 
Published: August 2013

Bioactive milk proteins may be important in protecting preterm infants from developing inflammation and necrotising enterocolitis (NEC). A preterm pig model was used to investigate the protective effects of enteral bovine lactoferrin (bLF) against NEC development and inflammation. Caesarean-delivered preterm pigs were fed parenteral and minimal enteral nutrition for the first 2 d followed by 2 d of total enteral nutrition before euthanasia. Pigs were stratified into two groups and fed with either a control formula (CON,n15) or a 10 g/l of bLF-enriched formula (LF,n13). NEC incidence, gut functions and inflammatory cytokines were analysed. NEC incidence and nutrient absorption were similar between the two groups. In pigs that developed NEC, disease outcome was more severe in the colon accompanied by increased intestinal permeability in LF pigs. In contrary, the LF pigs had a lowered IL-1β level in the proximal small intestine. Dose-dependent effects of bLF on cell proliferation, intracellular signalling and cytokine secretion were tested in porcine intestinal epithelial cells (PsIc1)in vitro.Low doses (0·1–1 g/l) increased cell proliferation via extracellular signal-regulated kinase (ERK), limited IL-8 secretion and prevented NF-κB and hypoxia-inducible factor-1α (HIF-1α) activation, suggesting anti-inflammatory effects. In contrast, at a higher dose (10 g/l), bLF exerted adverse effects by reducing cell proliferation, stimulating IL-8 release, inhibiting ERK activation and up-regulating NF-κB and HIF-1α activation. Overall, at a dose of 10 g/l, bLF exacerbated disease severity in pigs that developed NEC, while thein vitrostudies indicated the positive effects of bLF at low doses (0·1–1 g/l). Supplementation of infant formulas with bLF should therefore be optimised carefully.
Treatment of paediatric laryngeal papillomas: web survey of British Association of Paediatric Otolaryngologists
Authors: Manickavasagam J , Wu K , Bateman N D 
Published: August 2013

AbstractBackground and objective:Recurrent respiratory papillomatosis is the most common benign neoplasm of the larynx in children. Intralesional injection of cidofovir may have some potential as an adjunctive treatment. There is no standardised protocol in the UK for the management of recurrent respiratory papillomatosis. This study aimed to investigate the management practices of surgeons treating paediatric recurrent respiratory papillomatosis in the UK.Method:A web questionnaire survey was sent by e-mail to all members of the British Association of Paediatric Otorhinolaryngology.Results:Out of 35 respondents, 23 were at that time treating children with recurrent respiratory papillomatosis. Nineteen respondents preferred to use a microdebrider, 12 preferred laser, and 5 preferred cold steel along with either laser or a microdebrider. Twelve surgeons used cidofovir for selected patients and 12 surgeons did not use cidofovir for any patients. Cidofovir was considered after 0–4 surgical procedures by seven respondents, after 4–6 surgical procedures by four respondents and after 6 surgical procedures by six respondents. Eleven respondents warned patients about the possible side effects of cidofovir and five gave no warning.Conclusion:There was no consensus as to when it would be appropriate to use cidofovir, indicating the need for cidofovir usage guidelines.
The Global Cholera Pandemic Reaches Chinese Villages: Population Mobility, Political Control, and Economic Incentives in Epidemic Prevention, 1962–1964
Authors: FANG XIAOPING 
Published: August 2013

AbstractIn 1961 the seventh global cholera pandemic, El Tor cholera, broke out in Indonesia. Between 1962 and 1964, El Tor infected the southeast coastal areas of China. This pandemic occurred at a time of significant reorganization for both the rural medical and health systems and the people's communes following the failures of the Great Leap Forward. This paper explores how local governments led rural medical practitioners, health care workers, and villagers to participate in the campaign against the spread of El Tor cholera despite the readjustment and retrenchment of the people's communes as social, administrative, and political units. I argue that, during this period of flux, the local government strengthened its control over rural medical practitioners by institutionalizing their daily work practices and reducing their freedom of movement, whilst simultaneously providing incentives for health care workers to join the vaccination campaign. The people's communes and the household-registration system after 1961 put further restrictions on population mobility. This cellularization of village society greatly facilitated the vaccination, quarantine, and epidemic-reporting processes, and contributed to the formation of an epidemic-prevention system and eventually a response scheme for managing public health emergencies in rural China. This process reflected the complexity of the mutual interactions between the political and medical systems under socialism.
Riparian old-growth forests provide critical nesting and foraging habitat for Blakiston's fish owl Bubo blakistoni in Russia
Authors: Slaght Jonathan C. , Surmach Sergei G. , Gutiérrez R.J. 
Published: August 2013

AbstractConservation efforts for Blakiston's fish owl Bubo blakistoni in Russia are limited, partly because habitat use by these rare owls is poorly known. We therefore studied nesting and foraging habitat characteristics of Blakiston's fish owls in Primorye, Russia. We sampled habitat at 14 nest sites, 12 nest stand sites and 13 random sites; we also sampled rivers within 14 fish owl home ranges across our 20,213 km2 study area. We found that large old trees and riparian old-growth forest were the primary characteristics of nest and foraging sites, respectively. Large trees were probably used as nest sites because they have cavities large enough to accommodate these birds. Big trees are also important because they are primary sources of large woody debris in rivers, which enhances suitable habitat for salmon, the owl's primary prey. Based on habitat characteristics, nest sites were correctly distinguished from random sites 74% (Kappa = 0.48) of the time, nest stands from random sites 56% (Kappa = 0.12) of the time, and used sites from available foraging sites 68% (Kappa = 0.36) of the time. The management and conservation of old-growth forests is essential for sustaining this species because they are central to the owls' nesting and foraging behaviour. Moreover, conservation of these forests sustains habitat for many other species.
Generation and evolution of plasma during femtosecond laser ablation of silicon in different ambient gases
Authors: Chen Zhandong , Wu Qiang , Yang Ming , Tang Baiquan , Yao Jianghong , Rupp Romano A. , Cao Yaan , Xu Jingjun 
Published: August 2013

AbstractGeneration and evolution of plasma during femtosecond laser ablation of silicon are studied by steady-state and time-resolved spectroscopy in air, N2, SF6, and under vacuum. The plasma is generated faster than 200 ps (time resolution of our experiment) after excitation and mainly contains atoms and monovalent ions of silicon. Time-resolved spectra prove that silicon ions are faster than the silicon atoms which may be attributed to Coulomb repulsion and a local electric field when they are ejected from the silicon surface. During plasma evolution, ambient gas causes a confinement effect that enhances the dissociation of ambient gas molecules and the re-deposition of the removed material and leads to higher intensity and longer lifetime of the emission spectra. In SF6, a chemical reaction increases the plasma density and weakens the re-deposition effect. The different processes during plasma evolution strongly influence microstructure formation.
Laser interferometry measurements based calibration and error propagation identification for pose estimation in mobile robots
Authors: Jiménez Paulo A. , Shirinzadeh Bijan 
Published: August 2013

SUMMARYA widely used method for pose estimation in mobile robots is odometry. Odometry allows the robot in real time to reconstruct its position and orientation from the wheels' encoder measurements. Given to its unbounded nature, odometry calculation accumulates errors with quadratic increase of error variance with traversed distance. This paper develops a novel method for odometry calibration and error propagation identification for mobile robots. The proposed method uses a laser-based interferometer to measure distance precisely. Two variants of the proposed calibration method are examined: the two-parameter model and the three-parameter model. Experimental results obtained using a Khepera 3 mobile robot showed that both methods significantly increase accuracy of the pose estimation, validating the effectiveness of the proposed calibration method.
Practical feasibility of a high-precision 3-UPU parallel mechanism
Authors: Bhutani Gaurav , Dwarakanath T. A. 
Published: August 2013

SUMMARYIn this paper, we revisit the 3-degrees of freedom (DOF) pure translational mechanism. The mathematical model and the design considerations are discussed. A detailed sensitivity and error analysis is carried out and the results are discussed in a new perspective. The feasibility of the practical 3-DOF pure translational mechanism is established with novel design considerations to take care of theoretical mobility and geometrical constraints. We describe and validate the theoretical observations with stage-wise prototype models and experiments. The experimental results concur that all is well with 3-UPU in contrast to what is presented in refs. [6, 9, 10].
Older Adults with Acquired Brain Injury: Outcomes After Inpatient Rehabilitation
Authors: Chan Vincy , Zagorski Brandon , Parsons Daria , Colantonio Angela 
Published: August 2013

RÉSUMÉCette étude a examiné un profil basé sur la population des personnes âgées atteintes des lésions cérébrales acquises (LCA), et de leur résultats fonctionnels, en réadaptation en milieu hospitalier au Canada. Les personnes âgées de 65 ans et plus qui ont été admises en réadaptation en milieu hospitalier de soins aigus pour un traumatisme cranio-cérébrale (TCC) (n = 1 214) ou une lésion cérébrale non pas traumatique (nTCC) (n = 1 530) ont été identifiées en Ontario de 2003/04 à 2009/10. Les caractéristiques démographiques et cliniques et les notes fonctionnelles totales de l’instrument (FIMMD) ont eté examinées. On a utilisé le Base de données sur les congés des patients (BDCP) et le Système nationale d’information sur la réadaptation (SNIR). Les résultats ont montré que les personnes plus âgées atteintes d’un traumatisme cranio-cérébrale (TCC) présentaient un niveau d’indépendence fonctionelle plus élevé que celles sans TCC à l’admission et à la sortie. Cependant, les deux groupes ont faits des gains importants (p = .001) et similaires (p > .05). Nous concluons que les personnes âgées avec TCC et nTCC font des gains similaires de réadaptation en milieu hospitalier. L’incapacité fonctionnelle initiale plus faible des patients nTCC à l’admission et les profils cliniques différents offrent des implications pour la répartition des soins et des ressources cliniques.
Concordance between Self-Reported and Physician-Reported Chronic Co-morbidity among Disabled Older Adults
Authors: Iecovich Esther , Biderman Aya 
Published: August 2013

RÉSUMÉLa discordance entre les auto-rapports et les dossiers médicaux reflètent des éléments concernant les patients et les prestataires qui ont des implications pour la recherche et la gestion. Cette étude a examiné la discordance et les facteurs socio-démographiques qui expliquent la concordance. Un échantillon téléologique de 402 personnes âgées handicapées a été interrogés à l’aide d’un questionnaire structuré. On a trouvé les concordances les plus hauts pour le diabète, l’accident cardiovasculaire (CVA), et le cancer, et les plus bas pour l’arthrite, et les conditions rénales et digestives. Les facteurs explicatifs importants inclurent: (a) l’âge dans l’explication de la concordance dans l’hypertension; (b) l’ethnicité en expliquant la concordance dans l’arthrite et le cancer; (c) la situation de famille en expliquant la concordance dans les maladies de la thyroïde; (d) l’éducation pour expliquer la concordance dans les conditions gastro-intestinales, et (e) l’état fonctionnel en expliquant la concordance dans maladies respiratoires, gastro-intestinales et thyroïdiennes. La comorbidité a accrue la concordance dans toutes les conditions de santé, et a diminué la concordance pour l’hypertension. Une enquête plus poussée est nécessaire pour examiner la cause des disparités entre les deux sources d’information.
Ambulance Collisions in an Urban Environment
Authors: Saunders Charles E. , Heye Constance J. 
Published: August 2013

AbstractIntroduction:Decisions to send an ambulance with or without lights and siren are made every day. While travel with lights and siren is presumed to have relatively more risk associated with it than travel without, little epidemiologic analysis has been conducted to compare the two modes of travel or to characterize collisions in general.Objective:To characterize ambulance collisions and assess the risk of traveling with lights and siren in an urban 9-1-1 environment.Methods:Retrospective analysis of all consecutive ambulance collisions of the Paramedic Division of the San Francisco Department of Public Health during a 27-month period.Results:The overall collision rate for lights and siren (LS) travel was higher than that for non-lights and siren travel, although the difference was not statistically significant (45.9 collisions per 100,000 LS patient travels, 95% confidence limits 29.7, 62.1, versus 27.0/100,000 for non-LS travel, 95% confidence limits 18.3, 35.7). However, the rates of resulting injuries displayed a statistically significant difference (22.2 injuries per 100,00 LS patient travel, 95% confidence limits 11.0, 33.5, versus 1.5/100,000 for non-LS travel, 95% confidence limits −0.6, 3.5). While the majority of collisions (60.0%) occurred during patient-related travel, 35.6% occurred while the ambulance was available awaiting assignment, and 4.4% in a hospital parking lot. The majority of collisions were due to inattention, failure of on-coming traffic to yield, or unsafe parking; unsafe speed was an infrequent cause. Most crashes occurred during daylight, in dry weather, and involved another vehicle.Conclusion:There is some elevated risk for collision and added injury during lights and siren travel compared to travel without LS. The causes for these collisions suggest that interventions designed to improve driver skills and increase citizen awareness of an approaching ambulance could help reduce the number of collisions.
Structural typologies of salivary calculi
Authors: Nolasco P. , Anjos A.J. , Aquino Marques J.M. , Cabrita F. , Pereira M.F.C. , Alves de Matos A.P. , Carvalho P.A. 
Published: August 2013

Several theories have been put forward regarding the aetiology and pathogenesis of salivary calculi, although a comprehensive understanding of the nucleation and growth mechanisms involved in the formation of these structures is still lacking.In general, sialoliths present one core partially or highly mineralized surrounded by concentric layers of organic and mineralized matter that alternate in succession following a chronologic sequence. The layers consist of fine mineralized strata intercalated with fine organic ones and threaded globular structures with variable degrees of mineralization.The exact mechanism involved in the genesis of sialoliths remains largely unknown, theories defending an initial organic nidus or an initial precipitation of minerals, with subsequent deposition of organic and inorganic layers, can be found in the literature. Nevertheless, it remains object of discussion the etiologic factors responsible for the formation of the first nidus or the initial precipitation, since infection, inflammation of the gland, viscous nature of the mucous secretions or naturally existing sialomicroliths have all have been implicated.Aiming at an exhaustive systematization of salivary calculi morphogenesis, their morphology has been studied by micro-computed tomography (bCT) and scanning electron microscopy (SEM). CCT studies were done on as-extracted dried samples using uCT SkyScan 1172 instrument with a 1.3 Megapixel camera, operated at the maximum available power of the source (10W). Radiographs acquisition was performed with a rotational step in the 0.70-1° range, until a maximum of 180º, with an exposure time in the 3.1-5 s range. Microscopy observations were carried out with backscattered electron (BSE) signals using a JEOL JSM 7001F operated at 15 kV, samples were previously prepared following metallographic procedures.The submandibular and parotid calculi investigated presented similar growth patterns, which can follow either concentric (Figure 1) or perturbed-growth typologies (Figure 2), although in most situations a gradation between them has been found. Nevertheless, a single well-defined core constituted by material with low mineralization was frequently present, supporting the nucleation hypothesis of an initial organic nidus.The combination of TCT with SEM enabled a comprehensive characterization of the sialoliths: (i) the former technique allowed for a precise localization of the core and other morphological features within the calculus volume, while (ii) investigation of details at higher resolution could be achieved with the latter method. However, due to the friable nature of the sialoliths, handling during sample preparation results often in material loss (compare (a) and (b) in both Figures).The work was carried out with financial support of the Portuguese Foundation for Science and Technology through PTDC/SAU-ENB/111941/2009 and PEst-OE/CTM-UI0084/2011 grants.