bluuebunny/crossref_metadata_2025_split huggingface dataset:
Research and application of omics and artificial intelligence in cancer
Authors: Zhang Ye , Ma Wenwen , Huang Zhiqiang , Liu Kun , Feng Zhaoyi , Zhang Lei , Li Dezhi , Mo Tianlu , Liu Qing 
Published: July 2024

Abstract
Cancer has a high incidence and lethality rate, which is a significant threat to human health. With the development of high-throughput technologies, different types of cancer genomics data have been accumulated, including genomics, epigenomics, transcriptomics, proteomics, and metabolomics. A comprehensive analysis of various omics data is needed to understand the underlying mechanisms of tumor development. However, integrating such a massive amount of data is one of the main challenges today. Artificial intelligence (AI) techniques such as machine learning are now becoming practical tools for analyzing and understanding multi-omics data on diseases. Enabling great optimization of existing research paradigms for cancer screening, diagnosis, and treatment. In addition, intelligent healthcare has received widespread attention with the development of healthcare informatization. As an essential part of innovative healthcare, practical, intelligent prognosis analysis and personalized treatment for cancer patients are also necessary. This paper introduces the advanced multi-omics data analysis technology in recent years, presents the cases and advantages of the combination of both omics data and AI applied to cancer diseases, and finally briefly describes the challenges faced by multi-omics analysis and AI at the current stage, aiming to provide new perspectives for oncology research and the possibility of personalized cancer treatment.
Adaptive local boundary conditions to improve deformable image registration
Authors: Inacio Eloïse , Lafitte Luc , Facq Laurent , Poignard Clair , Denis de Senneville Baudouin 
Published: July 2024

Abstract

Objective. In medical imaging, it is often crucial to accurately assess and correct movement during image-guided therapy. Deformable image registration (DIR) consists in estimating the required spatial transformation to align a moving image with a fixed one. However, it is acknowledged that for DIR methods, boundary conditions applied to the solution are critical in preventing mis-registration. This poses an issue particularly when areas of interest are located near the image border. Despite the extensive research on registration techniques, relatively few have addressed the issue of boundary conditions in the context of medical DIR. Our aim is a step towards customizing boundary conditions to suit the diverse registration tasks at hand. Approach. We analyze the behavior of two typical global boundary conditions: homogeneous Dirichlet and homogeneous Neumann. We propose a generic, locally adaptive, Robin-type condition enabling to balance between Dirichlet and Neumann boundary conditions, depending on incoming/outgoing flow fields on the image boundaries. The proposed framework is entirely automatized through the determination of a reduced set of hyperparameters optimized via energy minimization. Main results. The proposed approach was tested on a mono-modal computed tomography (CT) thorax registration task and an abdominal CT-to-MRI registration task. For the first task, we observed a relative improvement in terms of target registration error of up to 12% (mean 4%), compared to homogeneous Dirichlet and homogeneous Neumann. For the second task, the automatic framework provides results close to the best achievable. Significance. This study underscores the importance of tailoring the registration problem at the image boundaries. In this research, we introduce a novel method to adapt the boundary conditions on a voxel-by-voxel basis, yielding optimized results in two distinct tasks: mono-modal CT thorax registration and abdominal CT-to-MRI registration. The proposed framework enables optimized boundary conditions in image registration without prior assumptions regarding the images or the motion.
A simplex path integral and a simplex renormalization group for high-order interactions
*
Authors: Cheng Aohua , Xu Yunhui , Sun Pei , Tian Yang 
Published: July 2024

Abstract
Modern theories of phase transitions and scale invariance are rooted in path integral formulation and renormalization groups (RGs). Despite the applicability of these approaches in simple systems with only pairwise interactions, they are less effective in complex systems with undecomposable high-order interactions (i.e. interactions among arbitrary sets of units). To precisely characterize the universality of high-order interacting systems, we propose a simplex path integral and a simplex RG (SRG) as the generalizations of classic approaches to arbitrary high-order and heterogeneous interactions. We first formalize the trajectories of units governed by high-order interactions to define path integrals on corresponding simplices based on a high-order propagator. Then, we develop a method to integrate out short-range high-order interactions in the momentum space, accompanied by a coarse graining procedure functioning on the simplex structure generated by high-order interactions. The proposed SRG, equipped with a divide-and-conquer framework, can deal with the absence of ergodicity arising from the sparse distribution of high-order interactions and can renormalize a system with intertwined high-order interactions at the p-order according to its properties at the q-order (

p
⩽
q

). The associated scaling relation and its corollaries provide support to differentiate among scale-invariant, weakly scale-invariant, and scale-dependent systems across different orders. We validate our theory in multi-order scale-invariance verification, topological invariance discovery, organizational structure identification, and information bottleneck analysis. These experiments demonstrate the capability of our theory to identify intrinsic statistical and topological properties of high-order interacting systems during system reduction.
The dynamical evolution of exciton-polaritons in asymmetric ring-step potential well
Authors: Dong Yifan , Ren Yuan , Li Xiuqian , Xiong Zhenyu , Song Tieling , Guo Aolin , Guo Longfei , Li Baili , Liu Peicheng , Wu Hao 
Published: July 2024

Abstract
The exciton-polariton, a quasi-particle formed by the coupling of excitons and photons, exhibits a semi-light-semi-matter nature, inheriting the advantages of both constituents and capable of achieving Bose-Einstein condensation at room temperature. This paper investigates the evolution of superposition states of semiconductor microcavity exciton-polariton Bose–Einstein condensate (BEC) within a ring-shaped structure. By employing theoretical modeling, the time-dependent dynamics of the superposition states of exciton-polaritons bound within a unique asymmetric ring-step potential well structure are analyzed, focusing on halide perovskite semiconductor materials. The study reveals correlations between the potential well structure of this step-like configuration and the transition of exciton-polariton BEC superposition states, shedding light on the evolution paths of BEC systems under specific structural influences and the fluctuation patterns of excitonic fields. These findings hold relevance for experimental manipulations of exciton-polariton superposition states within microcavities. This research demonstrates that ring-step potential well structures influence the excitation and evolution of exciton-polariton BEC superposition states, leading to transitions towards higher or lower order states. This transition is reflected macroscopically in alterations in the number and spatial distribution of interference petals in the superposition states. We consider initial states with orbital angular momentum quantum number l = 2, 3, 4, respectively. By exploiting the different structural relationships of ring-step potential wells, we achieve controlled evolutions of macroscopic occupation states, with interference petal numbers ranging from 4 to 6, 4–8, 6–8, 6–10, 8–10, 8–12, and 6–4.
Construction of fuzzy black holes and self-gravitational droplets in exponential f(R) gravity
Authors: Khan S , Yousaf Z 
Published: July 2024

Abstract
This paper discusses the construction of non-commutative geometry based self-gravitational droplets or fuzzy black holes (BHs) within the context of exponential-f(R) gravity model

1

β

e

β
R

−
1

, where β is a parameter with units [length
2]. Considering the Einasto density profile, a generalization of the Gaussian profile, we extend the noncommutative-inspired mini BH metric to incorporate dark matter (DM) as a constituent of the BH. We investigate various Einasto DM fuzzy objects filled with anisotropic fluid content, considering different values of the shape parameter and rescaled mass. This study investigates the possibility of stable self-gravitational compact objects with fuzzy mass distributions inspired by a well-known DM profile, the Einasto parametrization. These intriguing astrophysical configurations fall into three categories: fuzzy self-gravitational droplets with no event horizon, and fuzzy black holes featuring either one or two horizons. It is important to highlight that all these astrophysical entities are solutions derived from the exponential-f(R) gravity model. The corresponding effective potentials exhibit a significant resemblance to the effective potential of the classical Schwarzschild Black Hole located at the center of the Galaxy. Specifically, we investigate the potential for these black holes to serve as central galactic entities.
A wide angle beam scanning CRLH leaky-wave antenna with non-identical elements per unit-cells
Authors: Zamini H , Afsahi M , Dalili Oskouei H R , Mohammadi Shirkolaei M 
Published: July 2024

Abstract
In this research article, a wide-angle scanning leaky-wave antenna (LWA) based on the composite right/left-handed (CRLH) metamaterial (MTM) operating over the C-band spectrum for mobile applications is proposed, investigated, and realized. The proposed LWA includes nine CRLH-MTM-based unit-cells. The properties of CRLH-MTM have been applied using series slots and shunt metallic via-holes. Each unit cell consists of three patches, two external patches, and one smaller middle patch implemented between them. One slot has been etched on each external patch; the width of these two slots is unequal. Moreover, the distance of the middle patch with each side patch is different. The results show that using this method of realizing non-identical elements caused the achievement of proper return-loss at the transition frequency and provided the balanced CRLH metamaterial condition. Additionally, using CRLH-MTM properties by realizing series capacitance (slot) and shunt inductance (via-holes) made the wide-angle scant from backward to forward radiation pattern. The results demonstrate that the LW antenna with small dimensions of 251.5 × 30 × 1.575 mm3 operates over a frequency range of 4.8–6.13 GHz covering a wide beam scanning range from

−
63

°

to

+
6
5

°

with broadside radiation at the center frequency of 5.46 GHz. The radiation gain of the proposed antenna varies from 6.2–13.1 dB. The achievements confirm the effectiveness of the proposed methods to realize a high-performance LW-antenna with the advantages of simple design, low profile, low cost, and easy of manufacture for mobile applications.
Asymptotics for some logistic maps and the renormalization group
Authors: Faria da Veiga Paulo A , O’Carroll Michael 
Published: July 2024

Abstract
We explain the relation between the r = 1 case of the logistic map x

i+1 = r
x

i
(1 − x

i
),

x

i

∈
R

, i = 0, 1, 2, …, r > 0 and x
0 ≥ 0, and the renormalization group flow arising in the multiscale analysis of interesting zero fixed point, asymptotic free quantum field theory models such as the ultraviolet (1 + 1)-dimensional Gross-Neveu model and QCD, and the infrared

ϕ

4

4

model . We obtain the asymptotics of the mapping, which shows an inverse power decay approach to the fixed point x
* = 0, Gaussian fixed point, with additional logarithmic-like corrections. This asymptotic behavior is independent of the initial condition x
0 ∈ (0, 1) (hence, there is no constraint for x
0 to be small, as usual in quantum field models), and only depends on the lowest orders in a polynomial perturbation. In asymptotic free quantum field theory, this amounts to say that knowing the renormalization group β-function expansion in the coupling constant, up to higher orders, does not improve our knowledge of the asymptotics of the coupling flow. A comparison with a similar differential equation with continuous time is made by analyzing stability of this kind of solution and higher order monomial perturbations. We also obtain the detailed asymptotics for 0 < r < 1. As well, our methods can be applied when r ∈ (1, 3]. It is known, but without detailed asymptotics, that all trajectories with initial condition x
0 ∈ ( − 1, 1) converge to the fixed point x
* = (r − 1)/r. For r = 2, the super attractive case, we obtain an explicit exact solution which exhibits an exploding, non-constant exponential decay rate approach to the x
* = (1/2) fixed point. Our methods include the use of iterations, a discrete version of the Fundamental theorem of Calculus, a discrete version of the integrating factor method for first order linear ODEs and, sometimes, a scaling transformation. To obtain these results, we do not use the traditional Banach contraction mapping theorem, which only provides an upper bound on the asymptotics. We expect that our methods can be employed to determine the asymptotics of the logistic map for a wider range of parameters, where other fixed points are present.
Effect of Al substitution on the electron-phonon interaction for β-Ga2O3
Authors: Bhattacharjee Jayanta , Singh S D 
Published: July 2024

Abstract
The relevant parameters of electron–phonon (e-ph) interaction, like mean phonon temperature and e-ph interaction strength for Al-substituted β-Ga2O3, i.e., β-(AlxGa1–x)2O3 alloys, have been determined from the fitting of the temperature dependence of the band gap using Bose–Einstein empirical model. Both e-ph interaction strength and mean phonon temperature decrease sharply for initial Al compositions; then, they increase slightly and become more or less constant. This is explained by using the already existed concepts of propagon and diffuson for the phonon modes that interact with the electrons. Presence of two sublattices at the local level is found to be the origin of diffuson-like behaviour of phonon modes in β-(AlxGa1–x)2O3 alloyed system, which vibrate independently like a non-propagating oscillator and diffuse through the β-(AlxGa1–x)2O3 lattice. The diffuson-like behaviour of phonon modes in the β-(AlxGa1–x)2O3 alloy is found to be responsible for the reduction in e-ph interaction. The reduction of e-ph interaction strength of β-Ga2O3 with Al substitution may lead to the better performance of power devices working at higher temperatures.
Hysteresis gap-shrinking and structural effects of minor Al and Ti modifications on binary CuAl-based high-temperature shape memory alloys
Authors: Karaduman Oktay , Özkul İskender , Aksu Canbay Canan 
Published: July 2024

Abstract
Cu-based shape memory alloys (SMAs), except for exhibiting shape recovery, superelasticity, and high damping, are desirable because these smart materials have higher electrical and thermal conductivity and much lower prices than NiTi SMAs. However, they also have some downsides in mechanical strength and brittleness (mostly stemming from their coarse grain structure) and thermal instability. Therefore, adding some grain refining elements to these SMAs to improve their shape memory effect (SME), and thermal, structural, and mechanical properties is a widespread and simple way that significantly affects their martensitic phase transitions, structure, and mechanical properties. One of these grain-refining elements is titanium. Its thermal conductivity is lower than those of Cu and Al elements and has a low solubility in Cu-matrix. Besides the effects of small Al variations, the use of minor amounts of titanium in binary CuAl-base alloys can show impressive effects on all characteristics of these shape memory alloys, such as shape memory effect properties, martensitic transformation kinetics parameters, and microstructural features. In this research work, CuAlTi ternary high-temperature shape memory alloys (HTSMAs) with new compositions were produced by the arc melting method without a complicating use of Mn or Ni components in usual ternary CuAlMn and CuAlNi shape memory alloys. Thermal analyses of the prepared samples of the alloys were investigated by using differential scanning calorimetry (DSC) and differential thermal analysis (DTA) measurements. In contrast, x-ray diffraction (XRD) test results and optical micrographs were used for analyzing the structure of the alloy samples. The effect of different amounts of low soluble and grain refining Ti element on the binary CuAl alloy system was investigated.
Effect of void geometry and magnetic anisotropy in controlling the vortex in sub-micron annular Permalloy disc
Authors: Palabindela Praveen , Sinha Jaivardhan , Behera Bhaskar Chandra 
Published: July 2024

Abstract
Ferromagnetic rings, particularly asymmetric Permalloy (Py) rings are recognized as promising configurations for spintronic devices, offering additional degrees of freedom for manipulating magnetic states, especially in vortex configurations. Through micromagnetic simulations, our study explores the impact on magnetization states and spin configuration concerning ring symmetry, aligning with the interest in controlling vortex states for information storage. We initially obtained zero-field spin configurations by varying ring thickness (t), observing a 360° domain wall in rings with t < 12 nm and bi-vortex wall in rings with t ∼36 nm during magnetization reversal. Notably, an extended stability of the global-vortex state was observed in rings with t > 36 nm, indicating the dominance of global-vortex nucleation in thick asymmetric rings during domain wall movement. We investigate the hysteresis loops and spin configurations by varying the in-plane and out-of-plane anisotropy values. Our findings reveal the presence of multiple vortex cores with different polarities and sense of rotations in the ring for the in-plane anisotropy ∼30 to ∼40 kJ m−3. Additionally, a global-vortex with two vortex cores was formed due to demagnetization energy. We analysed the energy profile of stable magnetization states for various t and anisotropy values. Interestingly, the shape of the hysteresis loop changes significantly for the disc containing different shapes of void. Circular and square-shaped geometries suggest that the bi-vortex state is a stable configuration during magnetization reversal in both cases. The study also indicates the stability of the vortex with a square-shaped void geometry up to a sufficiently large field. For the case of triangular-shaped voids, the global-vortex state was favored with even the small fields. The estimated spin canting angles are found to be correlated with the presence of vortex spin configurations. Overall, these results are important for the development of magnetization vortex-based spintronics devices.
CLASS-OneLoop: accurate and unbiased inference from spectroscopic galaxy surveys
Authors: Linde Dennis , Dizgah Azadeh Moradinezhad , Radermacher Christian , Casas Santiago , Lesgourgues Julien 
Published: July 2024

AbstractThe power spectrum is the most commonly applied summary statistics to extract cosmological information from the observed three-dimensional distribution of galaxies in spectroscopic surveys. We presentCLASS-OneLoop, a new numerical tool, fully integrated into the Boltzmann codeCLASS, enabling the calculation of the one-loop power spectrum of biased tracers in spectroscopic surveys. Built upon the Eulerian moment expansion framework for redshift-space distortions, the implemented model incorporates a complete set of nonlinear biases, counterterms, and stochastic contributions, and includes the infrared resummation and the Alcock-Paczynski effect. The code features an evaluation of the loops by either direct numerical integration or Fast Fourier Transform, and employs a fast-slow parameter decomposition, which is essential for accelerating MCMC runs. After presenting performance and validation tests, as an illustration of the capabilities of the code, we apply it to fit the measured redshift-space halo power spectrum wedges on a ΛCDM subset of theAbacusSummitsimulation suite and considering scales up to kmax= 0.3h/Mpc. We find that the one-loop model adeptly recovers the fiducial cosmology of the simulation, while a simplified model commonly used in the literature for sensitivity forecasts yields significantly biased results. Furthermore, we conduct Monte Carlo Markov Chain (MCMC) forecasts for a DESI-like survey, considering a model with a dynamical dark energy component. Our results demonstrate the ability to independently constrain cosmological and nuisance parameters, even in the presence of a large parameter space with twenty-nine variables.
The anomaly of the CMB power with the latest Planck data
Authors: Billi M. , Barreiro R.B. , Martínez-González E. 
Published: July 2024

Abstract
The lack of power anomaly is an unexpected feature observed at large angular scales in the maps of Cosmic Microwave Background (CMB) produced by the COBE, WMAP and Planck satellites. This signature, which consists in a missing of power with respect to that predicted by the ΛCDM model, might hint at a new cosmological phase before the standard inflationary era.
The main point of this paper is taking into account the latest Planck polarisation data to investigate how the CMB polarisation improves the understanding of this feature. With this aim, we apply to the latest Planck data, both PR3 (2018) and PR4 (2020) releases, a new class of estimators capable of evaluating this anomaly by considering temperature and polarisation data both separately and in a jointly way. This is the first time that the PR4 dataset has been used to study this anomaly. To critically evaluate this feature, taking into account the residuals of known systematic effects present in the Planck datasets, we analyse the cleaned CMB maps using different combinations of sky masks, harmonic range and binning on the CMB multipoles.
Our analysis shows that the estimator based only on temperature data confirms the presence of a lack of power with a lower-tail-probability (LTP), depending on the component separation method, ≤ 0.33% and ≤ 1.76% for PR3 and PR4, respectively. To our knowledge, the LTP≤ 0.33% for the PR3 dataset is the lowest one present in the literature obtained from Planck 2018 data, considering the Planck confidence mask. We find significant differences between these two datasets when polarisation is taken into account most likely due to a different level of systematics. Especially, the analysis with PR3 data, unlike that with PR4, seems to point towards a lack of power at large scales also for polarisation.
Moreover, we also show that for the PR3 dataset the inclusion of the subdominant polarisation information provides estimates that are less likely accepted in a ΛCDM cosmological model than the only-temperature analysis over the entire harmonic-range considered. In particular, at ℓmax = 26, we found that no simulation has a value as low as the data for all the pipelines.
Reparametrization invariant action for gravity with dynamical determinant of metric
Authors: Klusoň J. 
Published: July 2024

Abstract
We present manifestly reparametrization invariant action for theory of gravity
with dynamical determinant of metric. We show that it is similar to a reparametrization invariant action for unimodular gravity. We determine canonical
form of the action and study structure of constraints.