bluuebunny/crossref_metadata_2025_split huggingface dataset:
Knotless Labral Repair Using the Inversion Technique in Hip Arthroscopy
Authors: Kolevar Matthew P. , Lingenfelter Cameron C. , Rocca Michael S. , Meredith Sean J. 
Published: August 2024

Background: Hip arthroscopy is technically demanding with a steep learning curve, and labral repair is an important component of the surgical treatment of femoroacetabular impingement (FAI) syndrome. As hip arthroscopy indications and techniques are evolving, it is important to remain focused on teaching techniques that are easily mastered and have a measurable benefit to patient outcomes. Indications: Patients with FAI syndrome and labral tear who have failed conservative treatment may benefit from hip arthroscopy, labral repair, and femoroplasty. Technique Description: Labral repair is an essential component of the surgical treatment of FAI syndrome. The hip is accessed in standard fashion, and multiple knotless anchors are used for labral repair. Repair sutures are passed around the labrum in an inverted fashion. This inversion technique ensures the labrum is not everted away from the acetabular rim and that the final position of the labrum will restore a good suction seal on the femoral head. Femoroplasty and capsule closure are always performed. Results: Patients can reliably expect improvements in hip pain and function. A cohort of 62 patients was investigated, and these patients demonstrated significant improvement in multiple patient-reported outcomes related to physical function, activity, and pain at 2 years after hip arthroscopy. Forty-seven percent stated they felt “completely better” at 2 years postoperatively. Discussion/Conclusion: Good hip arthroscopy technique in the proper patient can yield excellent results. The inversion labral repair technique reliably restores the suction seal and prevents eversion of the labrum to preserve normal function. Patient Consent Disclosure Statement: The author(s) attests that consent has been obtained from any patient(s) appearing in this publication. If the individual may be identifiable, the author(s) has included a statement of release or other written form of approval from the patient(s) with this submission for publication.
Time for health change: promoting community-based diabetes screening and prevention with video vignettes and social marketing
Authors: Jirjees Feras , Hasan Sanah , Krass Ines , Saidawi Ward , Al-Juboori Mohammed Khalid , Othman Amna M. , Alzoubi Karem H. , Alzubaidi Hamzah 
Published: August 2024

AbstractMeaningful communication between health service users and providers is essential. However, when stakeholders are unfamiliar with new health services, innovative communication methods are necessary to engage them. The aim of the study was to create, validate, and evaluate a video-vignette to enhance stakeholders’ (physicians, pharmacists, and laypeople) engagement and understanding of an innovative pharmacy-based diabetes screening and prevention program. Also, to assess the video-vignette’s capacity to measure appetite and appeal for such preventive programs. This mixed-methods study consisted of two phases. In phase one, a video-vignette depicting the proposed screening and prevention program was developed and validated following established international guidelines (n = 25). The video-vignette was then evaluated by stakeholders (n = 99). In phase two, the video-vignette’s capacity as a communication tool was tested in focus groups and interviews to explore stakeholders’ perspectives and engagement on the proposed service (n = 22). Quantitative data were analyzed descriptively, while qualitative data underwent thematic analysis. In total, 146 stakeholders participated. The script was well-received, deemed credible, and realistic. Furthermore, the video-vignette received high ratings for its value, content, interest, realism, and visual and audio quality. The focus groups and interviews provided valuable insights into the design and delivery of the new service. The video-vignette compellingly portrayed the novel pharmacy-based diabetes screening and prevention service. It facilitated in-depth discussions among stakeholders and significantly enhanced their understanding and appreciation of such health services. The video-vignette also generated significant interest in pharmacy-based diabetes screening and prevention programs, serving as a powerful tool to promote enrollment in these initiatives.
“Learn from Errors”: Post-traumatic growth among second victims
Authors: Huang Huanhuan , Liu Tong , Peng Ying , Du Xingyao , Huang Qi , Zhao Qinghua , Xiao Mingzhao , Luo Yetao , Zheng Shuangjiang 
Published: August 2024

Abstract
Background
Second victims, defined as healthcare providers enduring emotional and psychological distress after patient safety incidents (PSIs). The potential for positive transformation through these experiences is underexplored but is essential for fostering a culture of error learning and enhancing patient care.

Objective
To explore the level and determinants of post-traumatic growth (PTG), applying the stress process model.

Methods
The study was conducted at a tertiary general hospital in Chongqing, China. A descriptive, cross-sectional study design was used. A total of 474 s victims were included. An online survey was conducted in November 2021 to assess various factors related to the second victim experience. These factors included PSIs (considered as stressors), coping styles, perceived threats, and social support (acting as mediators), as well as the outcomes of second victim syndrome (SVS) and PTG. Statistical description, correlation analysis, and structural equation modeling were utilized for the data analysis. A p-value ≤ 0.05 was considered to indicate statistical significance.

Results
The participants reported moderate distress (SVS = 2.84 ± 0.85) and PTG (2.72 ± 0.85). The total effects on SVS of perceived threat, negative coping, social support, positive coping, and PSIs were 0.387, 0.359, -0.355, -0.220, and 0.115, respectively, accounting for 47% of the variation in SVS. The total effects of social support, positive coping, and PSIs on PTG were 0.355, 0.203, and − 0.053, respectively, accounting for 19% of the variation in PTG.

Conclusions
The study provides novel insights into the complex interplay between perceived threats, coping styles, and social support in facilitating PTG among second victims. By bolstering social support and promoting adaptive coping strategies, the adverse effects of PSIs can be mitigated, transforming them into opportunities for resilience and growth, and offering a fresh perspective on managing PSIs in healthcare settings.
How does online postal self-sampling (OPSS) shape access to testing for sexually transmitted infections (STIs)? A qualitative study of service users
Authors: Spence Tommer , Howarth Alison , Reid David , Sheringham Jessica , Apea Vanessa , Crundwell David , Day Sara , Dewsnap Claire , Jackson Louise , Mercer Catherine H. , Mohammed Hamish , Ross Jonathan D. C. , Sullivan Ann , Williams Andy , Winter Andrew , Wong Geoff , Burns Fiona , Gibbs Jo 
Published: August 2024

Abstract
Background
Sexually transmitted infections (STIs) are a serious public health issue in many countries. Online postal self-sampling (OPSS) is increasingly used to test for STIs, a trend accelerated by the COVID-19 pandemic. There remains limited understanding of how service users experience OPSS and what leads them to access it over clinic-based services, or vice versa. This research seeks to address these gaps, by undertaking a large qualitative study which sits within the ASSIST study, a mixed-methods, realist evaluation of OPSS.

Methods
Participants were recruited via clinic-based and online sexual health services in three case study areas in England. Purposive sampling was used to over-represent populations disproportionately affected by poor sexual health: young people; people of colour; men who have sex with men; and trans and non-binary people. Semi-structured interviews were analysed using Levesque’s conceptual framework of access to healthcare.

Results
We interviewed 100 service users. Participants typically became aware of OPSS from sexual health services, the internet or word of mouth. Acceptability of OPSS was facilitated by the perceived privacy it offered over clinic-based services, which some participants found embarrassing to access. OPSS also enabled participants to overcome barriers to reaching clinic-based services, such as a lack of appointment availability, although difficulty obtaining OPSS kits in some areas undermined this. As all services in our case study areas were free to use, affordability did not significantly shape access, although OPSS enabled some participants to avoid costs associated with travelling to clinic-based services. Participants were usually able to engage with OPSS, finding it easy to use and reliable, although blood self-sampling was challenging for most. Participants valued the support offered by clinic-based services beyond STI testing, including the opportunity to access contraception or ask staff questions, and felt this was more appropriate when they had specific concerns about their sexual health, such as STI symptoms.

Conclusions
Our findings constitute one of the largest qualitative studies to have explored OPSS and offer valuable insights to providers. OPSS shapes access to STI testing in a number of ways, including facilitating access in many circumstances, but users also want to retain access to clinic-based services, particularly for when they believe they need support beyond STI testing.
Clinical and radiological features associated with rupture of pulmonary artery pseudoaneurysm: a retrospective study
Authors: Liu Min , Liu Jixiang , Yu Wei , Gao Xiaoyan , Chen Shi , Qin Wei , Zhu Ziyang , Li Chenghong , Li Fajiu , Zhai Zhenguo 
Published: August 2024

Abstract
Background
Hemoptysis resulting from rupture of the pulmonary artery pseudoaneurysm (PAP) is massive and fatal, while factor contributing to the rupture of pseudoaneurysm remains elusive. This study aimed to elucidate the clinical and radiological features of PAP and identify the risk factors associated with rupture.

Methods
Patients who developed hemoptysis with PAP were collected from January 2019 to December 2022 retrospectively. Clinical data of the demographic characteristics, radiological findings, treatment strategies, and prognosis were collected. A comparative analysis was performed on the characteristics in the ruptured and non-ruptured cases.

Results
A total of 58 PAPs were identified in the 50 patients. The most common causes were infection (86%) and cancer (8%). The PAPs were located predominantly in the upper lobes of both lungs, and 57 (99.3%) were distributed in the segmental or subsegmental pulmonary arteries. The median diameter was 6.1(4.3–8.7) mm. A total of 29 PAPs were identified adjacent to pulmonary cavitations, with the median diameter of the cavity being 18.9 (12.4–34.8) mm. Rupture of pseudoaneurysm occurred in 21 cases (42%). Compared to unruptured group, the ruptured group had a significantly higher proportion of massive hemoptysis (57.1% vs. 6.9%, p < 0.001), larger pseudoaneurysm diameter (8.1 ± 3.2 mm vs. 6.0 ± 2.3 mm, p = 0.012), higher incidence of pulmonary cavitation (76.2% vs. 44.8%, p = 0.027), and larger cavitation diameters (32.9 ± 18.8 mm vs. 15.7 ± 8.4 mm, p = 0.005). The mean pulmonary artery pressure (mPAP) in the ruptured group was also significantly higher than that in the unruptured group [23.9 ± 7.4 mmHg vs. 19.2 ± 5.0 mmHg, p = 0.011]. Endovascular treatment was successfully performed in all 21 patients with ruptured PAP, of which the clinical success rate was 96.0%. Five patients experienced recurrent hemoptysis within one year.

Conclusions
Massive hemoptysis, pseudoaneurysm diameter, pulmonary cavitation, and elevated mPAP were the risk factors for rupture of pseudoaneurysm. Our findings facilitate early identification and timely intervention of PAP at high risk of rupture.
Post-race reactions: The emotional paradox of high performance and anxiety – a conventional content analysis
Authors: Augustsson Sofia Ryman , Bergh Malin , Petersson Kornelia 
Published: August 2024

Abstract
Background
Studies examining post-race emotional experiences in the context of endurance races among recreational athletes are scarce. The purpose of this study was to describe how recreational athletes experience the time after completing an endurance race.

Methods
In this study, a qualitative study design was used, and data collection was carried out with semi-structured interviews. The selection of subjects was completed systematically through criterion selection. The selection criteria were men and women, aged 18 years or older, who had completed an endurance race, and finished, lasting at least 180 min within the past 12 months. The interviews were analyzed using conventional qualitative content analysis.

Results
Sixteen recreational endurance athletes who, within six months, had completed an endurance race of running, cycling, cross-country skiing or Ironman, participated and were interviewed. Four overarching themes emerged from the analysis: “High on life”, “Loss of energy, Ambivalence and Melancholy”, “Activity-charged emotions”, and “Dimensions of emotions over time and new goals”, describing the content of the interviews.

Conclusions
Endurance athletes experienced varied post-race emotions that were both physically and mentally challenging, suggesting a holistic approach to managing post-race emotions would be beneficial. From the athletes’ perspectives, post-race feelings were dependent on many factors, including time spent training for a specific race, and perceived inability to set new goals for an upcoming training period. Setting future goals prior to an event may be a tool for reducing the risk of negative post-race emotions, including post-race blues.
Important aspects of experiences from patients and parents related to medications in Child and Adolescents Mental Health Services (CAMHS) - a qualitative study
Authors: Steiro Asbjørn Kulseng , Iversen Hilde Hestad 
Published: August 2024

Abstract
Purpose
Patient-reported experiences are a key source of information on quality in mental health care. Most patient experience surveys are limited to assessments from adults, including those conducted by parents or proxies on behalf of others. The aim of this study was to produce findings to inform development of modules on patient and parent experiences with medication in outpatient CAMHS in Norway, for use in previously validated instruments applied in national surveys.

Patients and methods
We developed survey questions based on a systematic literature review, expert-group consultations, interviews with adolescents and parents, and pretesting of the modules in a pilot study. This study included adolescents aged 12–17 years and parents with experiences from outpatient CAMHS and we present findings from semi-structured interviews.

Results
Adolescents with ADHD emphasized the following aspects as important concerning medication use in CAMHS: positive effects of medication like better function and concentration in school and change of behaviour. They also stressed the importance of side effects such as eating problems, nausea, loss of appetite, insomnia, and changes in thoughts and feelings. In addition, adolescents highlighted the significance of aspects as support in daily routines for taking medications, while parents highlighted needs for a professional follow-up care. Parents emphasized aspects regarding their children’s medication included both positive effects and change in behaviour, as well as their identification of negative side effects.

Conclusion
Our findings from semi-structured interviews identified important aspects reported by both patients and parents on functions, side effects and follow-up care related to medication. The results indicated that both groups emphasized corresponding aspects of what was important regarding medication. However, when it came to follow-up care, the two groups highlighted distinct aspects, indicating differing priorities or concerns in this area.
Perioperative chemotherapy with nivolumab for HER2-negative locally advanced gastric cancer: a case series
Authors: Toji Yuta , Takeuchi Shintaro , Ebihara Yuma , Kurashima Yo , Harada Kazuaki , Hayashi Mariko , Abe Hirotake , Wada Hideyuki , Yorinaga Satoko , Shichinohe Toshiaki , Tomaru Utano , Komatsu Yoshito , Hirano Satoshi 
Published: August 2024

Abstract
Background
Nivolumab with chemotherapy has been transformative for metastatic gastric cancer (GC). The potential of this regimen for local tumor control could be utilized for perioperative chemotherapy in locally advanced GC with bulky tumors or lymph node metastasis involving other organs.

Case presentation
Five patients with HER2-negative advanced GC were treated with nivolumab and oxaliplatin-based chemotherapy. All patients presented with clinical stage III or IVA GC with tumors in contact with either the pancreas or liver. Following chemotherapy, all tumors demonstrated shrinkage, allowing successful radical gastrectomies including four minimally invasive approach without postoperative complications. Four patients avoided combined resection of other organs.

Conclusions
Perioperative chemotherapy with nivolumab was effective for local disease control in this case series. This regimen could be a promising treatment approach for locally advanced GC; however, its survival benefits should be evaluated in clinical trials.
Deterministic modelling of implied volatility in cryptocurrency options with underlying multiple resolution momentum indicator and non-linear machine learning regression algorithm
Authors: Leung F. , Law M. , Djeng S. K. 
Published: August 2024

AbstractModeling implied volatility (IV) is important for option pricing, hedging, and risk management. Previous studies of deterministic implied volatility functions (DIVFs) propose two parameters, moneyness and time to maturity, to estimate implied volatility. Recent DIVF models have included factors such as a moving average ratio and relative bid-ask spread but fail to enhance modeling accuracy. The current study offers a generalized DIVF model by including a momentum indicator for the underlying asset using a relative strength index (RSI) covering multiple time resolutions as a factor, as momentum is often used by investors and speculators in their trading decisions, and in contrast to volatility, RSI can distinguish between bull and bear markets. To the best of our knowledge, prior studies have not included RSI as a predictive factor in modeling IV. Instead of using a simple linear regression as in previous studies, we use a machine learning regression algorithm, namely random forest, to model a nonlinear IV. Previous studies apply DVIF modeling to options on traditional financial assets, such as stock and foreign exchange markets. Here, we study options on the largest cryptocurrency, Bitcoin, which poses greater modeling challenges due to its extreme volatility and the fact that it is not as well studied as traditional financial assets. Recent Bitcoin option chain data were collected from a leading cryptocurrency option exchange over a four-month period for model development and validation. Our dataset includes short-maturity options with expiry in less than six days, as well as a full range of moneyness, both of which are often excluded in existing studies as prices for options with these characteristics are often highly volatile and pose challenges to model building. Our in-sample and out-sample results indicate that including our proposed momentum indicator significantly enhances the model’s accuracy in pricing options. The nonlinear machine learning random forest algorithm also performed better than a simple linear regression. Compared to prevailing option pricing models that employ stochastic variables, our DIVF model does not include stochastic factors but exhibits reasonably good performance. It is also easy to compute due to the availability of real-time RSIs. Our findings indicate our enhanced DIVF model offers significant improvements and may be an excellent alternative to existing option pricing models that are primarily stochastic in nature.
Vessel-based CTA-image to spatial anatomy registration using tracked catheter position data: preclinical evaluation of in vivo accuracy
Authors: Tangen Geir Arne , Aadahl Petter , Hernes Toril A. N. , Manstad-Hulaas Frode 
Published: August 2024

Abstract
Electromagnetic tracking of endovascular instruments has the potential to substantially decrease radiation exposure of patients and personnel. In this study, we evaluated the in vivo accuracy of a vessel-based method to register preoperative computed tomography angiography (CTA) images to physical coordinates using an electromagnetically tracked guidewire. Centerlines of the aortoiliac arteries were extracted from preoperative CTA acquired from five swine. Intravascular positions were obtained from an electromagnetically tracked guidewire. An iterative-closest-point algorithm registered the position data to the preoperative image centerlines. To evaluate the registration accuracy, a guidewire was placed inside the superior mesenteric, left and right renal arteries under fluoroscopic guidance. Position data was acquired with electromagnetic tracking as the guidewire was pulled into the aorta. The resulting measured positions were compared to the corresponding ostia manually identified in the CTA images after applying the registration. The three-dimensional (3D) Euclidean distances were calculated between each corresponding ostial point, and the root mean square (RMS) was calculated for each registration. The median 3D RMS for all registrations was 4.82 mm, with an interquartile range of 3.53–6.14 mm. A vessel-based registration of CTA images to vascular anatomy is possible with acceptable accuracy and encourages further clinical testing.

Relevance statement
This study shows that the centerline algorithm can be used to register preoperative CTA images to vascular anatomy, with the potential to further reduce ionizing radiation exposure during vascular procedures.

Key Points

Preoperative images can be used to guide the procedure without ionizing intraoperative imaging.

Preoperative imaging can be the only imaging modality used for guidance of vascular procedures.

No need to use external fiducial markers to register/match images and spatial anatomy.

Acceptable accuracy can be achieved for navigation in a preclinical setting.

Graphical Abstract
Research reviews on myosin head interactions with F-actin
Authors: Park Yoon Ho , Song Gang San , Jung Hyun Suk 
Published: August 2024

AbstractThe sliding filament theory and the cross-bridge model have been fundamental in understanding muscle contraction. While the cross-bridge model explains the interaction between a single myosin head and actin filament, the native myosin molecule consists of two heads. This review explores the possibility and mechanism of two-headed binding in myosin II to the actin. Recent studies using electron tomography and resonance energy transfer have provided evidence in support of the occurrence of two-headed binding. The flexibility of the regulatory light chain (RLC) appears to play a significant role in enabling this binding mode. However, high-resolution structures of the RLCs in the two-headed bound state have not yet been reported. Resolving these structures, possibly through sub-tomogram averaging or single-particle analysis, would provide definitive proof of the conformational flexibility of RLCs and their role in facilitating two-headed binding. Further investigations are also required to address questions such as the predominance of two-headed versus single-headed binding and the influence of the state of each of the heads on the other. An understanding of the mechanism of two-headed binding is crucial for developing a comprehensive model of the cross-bridge cycle of the native myosin molecule.