bluuebunny/crossref_metadata_2025_split huggingface dataset:
La production bio alimentaire distinctive en région québécoise : des territoires de ressources évoluant au rythme du cycle de vie de l'entreprise
Authors: Fortin Marie-José , Handfield Mario 
Published: April 2013

La localisation et l’ancrage des entreprises sont toujours l’objet de questionnement. Les théories sur les ressources et sur les systèmes productifs locaux invitent à examiner le travail individuel et collectif d’acteurs territoriaux, privés et publics, comme un facteur déterminant des dynamiques productives et économiques. Cette perspective est adoptée pour éclairer un contexte peu étudié, celui de trois régions québécoises. Les résultats d’une enquête menée auprès de 65 entreprises fabriquant des produits bioalimentaires distinctifs montrent la variété des ressources mobilisées par les dirigeants, se rapportant à l’entrepreneur, à la sphère productive, au milieu institutionnel et au milieu de vie. Parmi celles-ci, certaines apparaissent plus stratégiques lors de phases du cycle de vie de l’entreprise et qui réfèrent au territoire d’installation, au territoire d’action et au territoire d’avenir. En conséquence, les ressources associées au milieu de vie, y compris la famille élargie, mériteraient une attention dans les analyses, en complémentarité d’autres facteurs.
Penser la pluriactivité dans le Haut-Languedoc : registres de justification et dispositif d'accompagnement
Authors: Tallon Hélène , Dulcire Michel , Dubien Aurélie 
Published: April 2013

Cet article interroge les formes de légitimation de la pluriactivité sur lesquelles s’appuient les organismes de soutien aux projets d’activité d’un territoire. En Languedoc-Roussillon, de nombreux organismes de développement territorial et d’accompagnement s’intéressent à la pluriactivité, avec des visions parfois opposées sur ses impacts dans l’économie d’un territoire. Pour comprendre ces divergences, nous avons relevé les principaux registres de justification rencontrés en Languedoc-Roussillon, et dans un espace rural plus restreint, le Haut-Languedoc. Nous constatons que ces registres diffèrent de ceux énoncés par les pluriactifs eux-mêmes, et sont centrés autour de la capacité de résilience de la pluriactivité, véritable atout dans la gestion des crises mais qui la confine dans la dimension du « petit », associée à l’idée de « fragile ». Loin d’un « monde » cohérent, des visions politiques du travail divergentes s’expriment, avec lesquelles le dispositif d’accompagnement à la pluriactivité doit faire des compromis.
Géographie et transports publics locaux
Authors: Alderighi Marco , Gorla Gianluigi 
Published: April 2013

Géographie et transports publics locaux Cet article examine comment la géographie influe sur la performance des entreprises locales de transports publics en Italie. En utilisant des données sur 110 entreprises impliquées dans le transport urbain et interurbain, nous fournissons différentes estimations des frontières de coût stochastiques. Il en ressort que les variables géographiques influencent l’efficacité des entreprises. En particulier, nous constatons que le transport dans les régions métropolitaines et dans les zones de montagne révèle une perte d’efficacité de 15-21 % et de 15-18 %, respectivement.
The Effectiveness of Multilevel Promotion of Exclusive Breastfeeding in Rural Indonesia
Authors: Susiloretni Kun Aristiati , Krisnamurni Sri , Sunarto  , Widiyanto Santo Yosef Didik , Yazid Ahmad , Wilopo Siswanto Agus 
Published: April 2013

Purpose. To examine the effectiveness of multilevel promotion on exclusive breastfeeding (EBF) duration and prevalence. Design. A pretest-posttest control group design, quasi-experiment. Setting. Two public health centers in the Demak District, Central Java, Indonesia. Subjects. A total of 163 families were enrolled, including pregnant mothers, fathers, and grandmothers. Intervention. The multilevel promotion of EBF was conducted at the subdistrict, village, family, and individual levels. This was a complex intervention that modified breastfeeding determinants, integrated multidisciplinary partnerships, and involved community leaders (i.e., voluntary health workers, traditional birth attendants, Muslim scholars, and heads of villages). The strategies applied were advocacy, training, media, and home visit counseling. Measures. EBF duration and prevalence. Analysis. Survival analyses, Cox proportional-hazard model. Results. The duration of EBF increased after the multilevel promotion. The median postintervention duration in the intervention group was 18 weeks compared with .1 week in the control group (p < .001). The prevalence of EBF at 1, 8, 16, and 24 weeks for the intervention versus control groups was 75.3% vs. 28.0%, 64.2% vs. 14.6%, 50.6% vs. 8.5%, and 37.0% vs. 3.7%, respectively (p < .001). Mothers in the control group were three times more likely to stop exclusive breastfeeding per unit of time than were mothers in the intervention group (adjusted hazard ratio 3.01; 95% confidence interval: 1.96, 4.63). Conclusion. Multilevel promotion can prolong the duration and increase the prevalence of EBF.
The Association of Predeployment and Deployment-Related Factors on Dimensions of Postdeployment Wellness in U.S. Military Service Members
Authors: Bagnell Melissa E. , LeardMann Cynthia A. , McMaster Hope S. , Boyko Edward J. , Smith Besa , Granado Nisara S. , Smith Tyler C. 
Published: April 2013

Purpose. To assess the effects of predeployment and deployment-related factors on dimensions of wellness following deployment. Design. Prospective longitudinal study. The dependent variable was dimensions of wellness. Independent variables were measured in terms of modifiable, nonmodifiable, and military factors, such as sex, race/ethnicity, service branch, smoking status, and combat experience. Setting. A large military cohort participating in the Millennium Cohort Study. Subjects. Included 10,228 participants who deployed in support of the operations in Iraq and Afghanistan. Measures. Dimensions of wellness were measured by using standardized instruments assessing self-reported physical health, mental health, and stress. Covariates were measured by using self-reported and electronic data. Analysis. Factors of postdeployment wellness were assessed by using ordinal logistic regression. Results. Most participants (78.7%) were categorized as “moderately well” post deployment. Significant modifiable predeployment predictors of postdeployment wellness included normal/underweight body mass index (odds ratio [OR] = 1.72, p < .05). Military factors significantly associated with wellness included not experiencing combat (OR = .56, p < .05), member of Air Force (OR = 2.02, p < .05) or Navy/Coast Guard (OR = 1.47, p < .05), and combat specialist occupation (OR = 1.22, p < .05). Conclusion. Multiple modifiable factors associated with postdeployment wellness were identified, which may help inform medical and military leadership on potential strategies to ensure a well force. Those trained in combat roles were more likely to be well post deployment though this apparent benefit was not conferred onto those reporting combat experiences.
Predictors of Voluntary Home-Smoking Restrictions and Associations with an Objective Measure of In-Home Smoking among Subsidized Housing Tenants
Authors: Hood Nancy E. , Wewers Mary Ellen , Ferketich Amy K. , Klein Elizabeth G. , Pirie Phyllis 
Published: April 2013

Purpose. Examine predictors of voluntary home-smoking restrictions (HSRs) and associations with an objective measure of in-home smoking. Design. Cross-sectional. Setting. Publicly subsidized multiunit housing units managed by private company in Columbus, Ohio, without a smoke-free housing policy. Subjects. Probability sample of primary leaseholders (N = 301, 64% response rate). Measures. Self-reported knowledge, attitudes, and behaviors collected during face-to-face survey in fall 2011, including individual (e.g., knowledge of health effects), social (e.g., number of friends who smoke), and environmental (e.g., safety) factors hypothesized to be related to having HSRs. Surface nicotine concentration (μg/m2) based on samples collected from wood surface in respondents' living rooms (n = 279). Analysis. Multiple linear and logistic regression were used to identify factors associated with having HSRs and with indoor surface nicotine concentrations. Results. Fewer than one-third (29.2%) of tenants had complete HSRs, while more than half (55.8%) had partial restrictions. Several individual and social factors, but no environmental/community factors, were associated with having HSRs. Type of HSRs (p < .001) and smoking status (p < .001) were independently associated with mean surface nicotine concentrations. Conclusion. Few subsidized housing tenants voluntarily limit in-home smoking. Partial restrictions could be considered as a harm reduction strategy but may be less effective among smokers. Strategies to change social norms are also needed to modify in-home smoking behavior among subsidized housing tenants.
National Implementations of Legal Deposit
Authors: Stephens Andy , Gibby Richard 
Published: April 2013

In 2011, the Conference of Directors of National Libraries commissioned the authors to undertake an international survey of its membership: to establish the current state of legal deposit, or equivalent arrangements in all national libraries participating in the Conference of Directors of National Libraries including both the extent of legal deposit coverage and also how the deposited material may be used; and to identify any key lessons or principles which could be used for advocacy or to inform planning with regard to legal deposit. This paper reports the findings of that survey. The results confirm that e-legal deposit is now widespread at least for publications on CD-ROM and there is real traction towards securing e-legal deposit for web and electronic publications. However, it would appear that the terms of access to electronic publications under legal deposit are often more restrictive than for print or for original publication. Respondents also proposed a number of principles and advocacy points and these informed the development of an advocacy pack to be used by those national libraries seeking to secure the legal deposit of electronic publications. These advocacy points are reproduced in an Appendix to the paper.
pH‐Dependent Anticancer Drug Release from Silk Nanoparticles
Authors: Seib F. Philipp , Jones Gregory T. , Rnjak‐Kovacina Jelena , Lin Yinan , Kaplan David L. 
Published: April 2013

AbstractSilk has traditionally been used as a suture material because of its excellent mechanical properties and biocompatibility. These properties have led to the development of different silk‐based material formats for tissue engineering and regenerative medicine. Although there have been a small number of studies about the use of silk particles for drug delivery, none of these studies have assessed the potential of silk to act as a stimulus‐responsive anticancer nanomedicine. This report demonstrates that an acetone precipitation of silk allows the formation of uniform silk nanoparticles (98 nm diameter, polydispersity index 0.109), with an overall negative surface charge (–33.6 ± 5.8 mV), in a single step. Silk nanoparticles are readily loaded with doxorubicin (40 ng doxorubicin/μg silk) and show pH‐dependent release (pH 4.5≫ 6.0 > 7.4). In vitro studies with human breast cancer cell lines demonstrates that the silk nanoparticles are not cytotoxic (IC50 > 120 μg mL−1) and that doxorubicin‐loaded silk nanoparticles are able to overcome drug resistance mechanisms. Live cell fluorescence microscopy studies show endocytic uptake and lysosomal accumulation of silk nanoparticles. In summary, the pH‐dependent drug release and lysosomal accumulation of silk nanoparticles demonstrate the ability of drug‐loaded silk nanoparticles to serve as a lysosomotropic anticancer nanomedicine.
Recent advances in low‐cost carbon fiber manufacture from lignin
Authors: Baker Darren A. , Rials Timothy G. 
Published: April 2013

ABSTRACTThe confluence of two US energy policy mandates, the 2012 Corporate Average Fuel Economy Standards and Renewable Fuels Standard #2, provide the opportunity to examine the possibility of high‐value materials from lignin with increased depth. In this case, the desire to provide lighter, low‐cost materials for automobiles to reduce fuel consumption, and to improve the economics of biorefineries for fuel production, have led to an increased interest in low‐cost carbon fiber manufacture from lignin. For this review the authors provide the context of subject matter importance, a cost comparison of potential low‐cost carbon fibers, a brief review of historical work, a review of more recent work, and a limited technical discussion followed by recommendations for future directions. As the available material for review is limited, the author includes many references to publicly available government documents and reviewed proceedings that are generally difficult to locate. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 130: 713‐728, 2013
Heterometallic Mixed‐Valence Copper(I,II) Cyanides that were Tuned by Using the Chelate Effect: Discovery of Famous Cairo Pentagonal Tiling and Unprecedented (3,4)‐Connected {83}2{86} Topological 3D Net
Authors: Qin Ying‐Lian , Yao Ru‐Xin , Wu Guo‐Xing , Liu Min‐Min , Zhang Xian‐Ming 
Published: April 2013

AbstractBy using environmentally friendly [Ni(CN)4]2− as a cyanide source, three new heterometallic cyano‐bridged mixed‐valence CuI/CuII coordination polymers with three different electronic configurations (d8–d10), that is, [Cu2Ni(CN)5(H2O)3] (1), [Cu2Ni(CN)5(pn)H2O] (2), and [Cu3Ni(CN)6(pn)2] (3, pn=1,2‐propane diamine) have been synthesized by gradually increasing the amount of pn. Compound 1, which was hydrothermally synthesized in the absence of pn ligand, exhibits the famous 2D Cairo pentagonal tiling, in which the CuI, CuII, and NiII atoms act as trigonal, T‐shaped, and square‐planar nodes, respectively. Notably, there are three water molecules located at the meridianal positions of the octahedrally coordinated CuII atom in compound 1. A similar reaction, except for the addition of a small amount of pn, generated a similar Cairo pentagonal tiling layer in which two of the water molecules that were located at the meridianal positions of the octahedrally coordinated CuII atom were replaced by a chelating pn group. Another similar hydrothermal reaction, with the addition of a larger amount of pn, yielded compound 3, which showed a related two‐fold‐interpenetrated (3,4)‐connected 3D framework with an unprecedented {83}2{86} topology in which the CuII atom was chelated by two pn groups. These structural changes between compounds 1, 2, 3 can be explained by the chelating effect of the pn group. The replacement of two meridianally coordinated water molecules on the octahedral CuII atom in compound 1 by a pn group gives compound 2, which shows similar Cairo tiling, and a further increase in the amount of pn results in the formation of the [Cu(NC)2(pn)2] unit and the two‐fold‐interpenetrated 3D framework of compound 3. The mixed‐valence properties of compounds 1, 2, and 3 were confirmed by variable‐temperature magnetic‐susceptibility measurements.
Global gene expression analysis of Saccharomyces cerevisiae grown under redox potential‐controlled very‐high‐gravity conditions
Authors: Liu Chen‐Guang , Lin Yen‐Han , Bai Feng‐Wu 
Published: April 2013

AbstractRedox potential (ORP) plays a pivotal role in yeast viability and ethanol production during very‐high‐gravity (VHG) ethanol fermentation. In order to identify the correlation between redox potential profiles and gene expression patterns, global gene expression of Saccharomyces cerevisiae was investigated. Results indicated that significant changes in gene expression occurred at the periods of 0 ‐ 6 h and 30 ‐ 36 h, respectively. Changes noted in the period of 0 ‐ 6 h were mainly related to carbohydrate metabolism. In contrast, gene expression variation at 30 ‐ 36 h could be attributed primarily to stress response. Although CDC19 was down‐regulated, expression of PYK2, PDC6 and ADH2 correlated inversely with ORP. Meanwhile, expression of GPD1 decreased due to the depletion of dissolved oxygen in the fermentation broth, but expression of GPD2 correlated with ORP. Transcription of genes encoding heat shock proteins was characterized by uphill, downhill, valley and plateau expression profiles, accordingly to specific function in stress response. These results highlight the role of ORP in modulating yeast physiology and metabolism under VHG conditions.
Sexually Violent Predators: Toward Reasonable Estimates of Recidivism Base Rates
Authors: Neller Daniel J. , Petris Giovanni 
Published: April 2013

ABSTRACTThe sexual recidivism rate of sex offenders is a controversial issue. Perhaps as controversial is the sexual recidivism rate of the select group of sex offenders who are examined pursuant to sexually violent predator (SVP) statutes. At present, reliable estimates of SVP recidivism are unavailable. We propose that reasonable estimates of SVP recidivism can be reached by considering three available pieces of data: (i) a likely recidivism rate of the general population of sex offenders; (ii) procedures typically followed by jurisdictions that civilly commit sex offenders; and (iii) classification accuracy of procedures. Although sexual recidivism rates vary across jurisdictions, the results of our analyses suggest sex offenders referred for examination pursuant to SVP statutes recidivate at substantially higher rates than typical sex offenders. Our results further suggest that sex offenders recommended for commitment as SVPs recidivate at even greater rates than SVP respondents who are not recommended for commitment. We discuss practice and policy implications of these findings. Copyright © 2013 John Wiley & Sons, Ltd.
Integrating a learning constructionist environment and the instructional design approach into the definition of a basic course for embedded systems design
Authors: Cano E. M. , Ruiz J. G. , Garcia I. A. 
Published: April 2013

AbstractThe benefits of the constructionist theory as a learning paradigm are widely recognized, among other reasons, because it offers to instructional designers an alternative set of values that may significantly influence and provide consistency to any Instructional System Design (ISD) model. Relevant characteristics of the two approaches are described to identify the real necessities of undergraduate students to avoid deficiencies in static classrooms; these characteristics support significant learning environments where students of IT‐related curricula are actively related to implementing their own public artifacts, passing through passive to active learning states. Thus, from our perspective the constructionist theory in combination with an ISD model can be useful in developing an embedded systems course for undergraduate education. This approach is supported by a software/hardware tool that was created to enhance the teaching–learning process through hands‐on experimentation. Finally, the results of a comprehensive assessment of the course effectiveness are presented. © 2013 Wiley Periodicals, Inc. Comput Appl Eng Educ 23:36–53, 2015; View this article online at wileyonlinelibrary.com/journal/cae; DOI 10.1002/cae.21574
Mechanistic Aspects of hSOD1 Maturation from the Solution Structure of CuI‐Loaded hCCS Domain 1 and Analysis of Disulfide‐Free hSOD1 Mutants
Authors: Banci Lucia , Cantini Francesca , Kozyreva Tatiana , Rubino Jeffrey T. 
Published: April 2013

AbstractSuperoxide dismutase 1 (SOD1) maturation within the cell is mainly accomplished with the SOD1‐specific chaperone, CCS, a dimeric protein with three distinct domains in each monomer. We recently showed that the first domain of human CCS (hCCSD1) is responsible for copper transfer to its protein partner, human SOD1 (hSOD1). The NMR solution structure of the copper(I)‐loaded form of hCCSD1 reported here contributes further to characterization of the copper‐transfer mechanism to hSOD1. NMR spectroscopy was also used to examine the hSOD1 mutants C57A, C146A, and C57A/C146A, which are unable to form the structurally conserved disulfide bond in SOD1, in order to investigate the role of these cysteines during hSOD1 copper acquisition. Together, the information on both hCCS and hSOD1, along with a sequence analysis of eukaryotic CCSD1, allows us to propose important mechanistic aspects regarding the copper‐transfer process from hCCS to hSOD1.
Materials Discovery and Crystal Growth of Zeolite A Type Zeolitic–Imidazolate Frameworks Revealed by Atomic Force Microscopy
Authors: Cubillas Pablo , Anderson Michael W. , Attfield Martin P. 
Published: April 2013

AbstractA new zeolitic–imidazolate framework (ZIF), [Zn(imidazolate)2−x(benzimidazolate)x], that has the zeolite A (LTA) framework topology and contains relatively inexpensive organic linkers has been revealed using in situ atomic force microscopy. The new material was grown on the structure‐directing surface of [Zn(imidazolate)1.5(5‐chlorobenzimidazolate)0.5] (ZIF‐76) crystals, a metal–organic framework (MOF) that also possesses the LTA framework topology. The crystal growth processes for both [Zn(imidazolate)2−x(benzimidazolate)x] and ZIF‐76 were observed using in situ atomic force microscopy; it is the first time the growth process of a nanoporous material with the complex zeolite A (LTA) framework topology has been monitored temporally at the nanoscale. The results reveal the crystal growth mechanisms and possible surface terminations on the {100} and {111} facets of the materials under low supersaturation conditions. Surface growth of these structurally complex materials was found to proceed through both “birth‐and‐spread” and spiral crystal‐growth mechanisms, with the former occurring through the nucleation and spreading of metastable and stable sub‐layers reliant on the presence of non‐framework species to bridge the framework during formation. These results support the notion that the latter process may be a general mechanism of surface crystal growth applicable to numerous crystalline nanoporous materials of differing complexity and demonstrate that the methodology of seeded crystal growth can be used to discover previously unobtainable ZIFs and MOFs with desirable framework compositions.
Enantiomeric Fraction Determination of 2‐Arylpropionic Acids in a Package Plant Membrane Bioreactor
Authors: Hashim Nor H. , Stuetz Richard M. , Khan Stuart J. 
Published: April 2013

ABSTRACTEnantiomeric compositions of three 2‐arylpropionic acid (2‐APA) drugs, ibuprofen, naproxen, and ketoprofen, were monitored in a membrane bioreactor (MBR) treating municipal effluent in a small rural town in Australia. Specific enantiomers were determined as amide diastereomers using the chiral derivatizing reagent, (R)‐1‐phenylethylamine (PEA), followed by gas chromatography–tandem mass spectrometry (GC‐MS/MS). The six individual enantiomers were quantified by isotope dilution and the enantiomeric fractions (EFs) were determined. Over four separate sampling events, ibuprofen EF ranged from 0.88 to 0.94 (median 0.93) in the influent and 0.38 to 0.40 (median 0.39) in the effluent. However, no significant change in ketoprofen EF was observed, with influent EFs of 0.56–0.60 (median 0.58) and effluent EFs 0.54–0.68 (median 0.56). This is the first report of enantiospecific analysis of ketoprofen in municipal wastewater and it is not yet clear why such different behavior was observed compared to ibuprofen. Naproxen EF was consistently measured at 0.99 in the influent and ranged from 0.86 to 0.94 (median 0.91) in the effluent. This study demonstrates that EF is a relatively stable parameter and does not fluctuate according to concentration or other short‐term variables introduced by sampling limitations. The enantiospecific analysis of chiral chemicals presents a promising approach to elucidate a more thorough understanding of biological treatment processes and a potential tool for monitoring the performance of key biological pathways. Chirality 25:301–307, 2013. © 2013 Wiley Periodicals, Inc.