bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prenatal diagnosis of haemoglobinopathies: our experience of 523 cases
Authors: Grosso Michela , Puzone Stella , Storino Maria Rosaria , Sessa Raffaele , Izzo Paola 
Published: April 2013

Abstract

Background: We performed counselling for prenatal diagnosis (PD) of haemoglobinopathies in 372 couples. Thirty-four out of 372 (9.1%) did not undergo PD: six due to spontaneous abortion; nine because it was too difficult to make a decision if PD was positive; 18 because counselling excluded the carrier status of one or both parents; and one because parental mutations were mild.

Methods: Eleven out of 338 (3.3%) couples underwent PD because they had a thalassaemic child; 106 (31.4%) were found to be at high risk during pre-conceptional screening; 221 (65.4%) because of familiarity. Of 523 PDs in 486 (92.9%), including six dichorionic twin pregnancies, PD was performed on DNA from chorionic villi (CV), and in 37 from amniocytes (7.1%). In 1/523 cases, PD was not completed because DNA from CV was not sufficient; in two cases single tandem repeat analysis revealed maternal contamination of foetal DNA; in 7/522 (1.3%) cases PD revealed non-paternity. In 435/522 (83.3%) cases, PD was performed using reverse dot-blot and ARMS; 34/522 (6.5%) required sequencing. In 53/522 (10.2%) cases it was necessary to test globin loci for large rearrangements.

Results: One hundred and twenty out of 522 (23.0%) PDs revealed an affected foetus. In all but two cases the couple interrupted pregnancy. In the six twin pregnancies PD revealed a normal and a carrier foetus (two cases), carrier status in both foetuses (two cases) and a carrier and an affected foetus (two cases). In these latter cases the couple planned selective interruption.

Conclusions: Our PD procedure is successful and reliable, and is useful in high-risk areas characterised by molecular heterogeneity.
Symplectic geometry and rationally connected 4-folds
Authors: Tian Zhiyu 
Published: April 2013

Abstract

We study some symplectic geometric aspects of rationally connected 4-folds. As a corollary, we prove that any smooth projective 4-fold symplectic deformation equivalent to a Fano 4-fold of pseudo-index at least 2 or a rationally connected 4-fold whose second Betti number is 2 is rationally connected.
A p-adic Eisenstein measure for unitary groups
Authors: Eischen Ellen E. 
Published: April 2013

Abstract

We construct a p-adic Eisenstein measure with values in the space of p-adic automorphic forms on certain unitary groups. Using this measure, we p-adically interpolate certain special values of both holomorphic and non-holomorphic Eisenstein series, as both the archimedean and the p-adic weights of the Eisenstein series vary.
Prenatal ultrasound and molecular diagnosis elucidate the prognosis of Pfeiffer syndrome1)
Authors: Jelin Angie C. , Chang Jin , Feldstein Vickie , Rauen Katherine A. 
Published: April 2013

Abstract

Background: Pfeiffer syndrome (PS) is one of several related craniosynostosis and occurs in 1 out of every 100,000 births. The diagnosis has historically been based on the clinical neonatal findings of bilateral coronal craniosynostosis, midface hypoplasia, with broad thumbs and great toes.

Case: A craniosynostosis suggestive of PS was identified on prenatal ultrasound at 34+3 weeks gestation by findings of polyhydramnios, a cloverleaf skull, ventriculomegaly, hypertelorism, marked orbital proptosis, short limbs, broad digits, and an abnormality of the spine. Prenatal molecular testing of the FGFR genes revealed an exon 10, p.Y340C mutation in the FGFR2 gene.

Conclusion: PS can now be diagnosed prenatally. In our case, the specific mutation was associated with an especially severe phenotype. The ultrasonographic findings in conjunction with the molecular diagnosis allowed us to better inform the patient and medical staff about the diagnosis and prognosis.
The geographical distribution of typologically diverse comparative constructions of superiority in Purepecha
Authors: Chamoreau Claudine 
Published: April 2013

Abstract
This paper explores the relations between three domains dealing with linguistic variation: dialectology, typology, and contact linguistics. It aims to contribute to dialectal research that also considers syntactic questions, exploring the syntactic domain of comparative constructions of superiority in Purepecha (a language isolate spoken in Mexico). I demonstrate that the expression of the comparison of superiority can be mapped onto the language by means of ten constructions, which may be divided into four types, showing that language contact can lead to the emergence of new types. This study points out that the consequences of language contact are not homogeneous, but fall into various types of construction aligned with local specificities and geographical distribution. I argue that the integration of dialectology, typology, and contact linguistics results in a dynamic and multidimensional organization, which I characterize as a multi-layered perspective.
Orthogonality of polynomials and orthosymmetry
Authors: Toumi Mohamed Ali 
Published: April 2013

Abstract
Orthogonality of homogeneous orthogonally additive polynomials and
orthosymmetry of multilinear maps are in general independent properties. In
this paper, we show, for some important vector lattices, that the vector space
of all orthogonally additive scalar-valued polynomials and the vector space of
orthosymmetric scalar-valued multilinear maps are isomorphic.
Upper triangular matrices and operations in odd primary connective K-theory
Authors: Stanley Laura , Whitehouse Sarah 
Published: April 2013

Abstract
We prove analogues for odd primes of results of Snaith and Barker–Snaith. Let ℓ denote the p-complete connective Adams summand and consider
the group of left ℓ-module automorphisms of ℓ∧ℓ in the stable homotopy category
which induce the identity on mod p homology. We prove a group isomorphism between this group and a certain group
of infinite invertible upper triangular matrices with entries in the p-adic integers. We determine information about the matrix corresponding to the automorphism 1∧Ψ
q
of ℓ∧ℓ,
where Ψ
q
is the Adams operation and q is an integer which generates the p-adic units.
Cluster tilting vs. weak cluster tilting in Dynkin type A infinity
Authors: Holm Thorsten , Jørgensen Peter 
Published: April 2013

Abstract
This paper shows a new phenomenon in higher cluster tilting theory. For each positive integer d, we exhibit a triangulated category
𝖢 with the following properties.

On the one hand, the d-cluster tilting subcategories of 𝖢 have
very simple mutation behaviour: Each indecomposable object has
exactly d mutations. On the other hand, the weakly d-cluster
tilting subcategories of 𝖢 which lack functorial finiteness can
have much more complicated mutation behaviour: For each 0 ≤ ℓ
≤ d - 1, we show a weakly d-cluster tilting subcategory

𝖳
ℓ

${\mathsf {T}_{\ell }}$

which has an indecomposable object with precisely
ℓ mutations.

The category 𝖢 is the algebraic triangulated category generated
by a (d + 1)-spherical object and can be thought of as a higher
cluster category of Dynkin type A
∞.
Solving quintic equations by two-fold origami
Authors: Nishimura Yasuzo 
Published: April 2013

Abstract
It is known that a general quintic equation cannot be solved by an
ordinary origami construction. Alperin and Lang showed that three simultaneous folds leads to a solution
of the general quintic equation. In this paper we improve their result and show that two simultaneous folds
are sufficient to solve the general quintic equation.
The moduli space of 4-dimensional non-nilpotent complex associative algebras
Authors: Fialowski Alice , Penkava Michael 
Published: April 2013

Abstract
In this paper, we study the moduli space of 4-dimensional complex
associative algebras. We use extensions to compute the moduli space,
and then give a decomposition of this moduli space into strata consisting
of complex projective orbifolds, glued together through jump deformations. Because the space of 4-dimensional algebras is large, we only classify the non-nilpotent algebras in this paper.
Languages associated with saturated formations of groups
Authors: Ballester-Bolinches Adolfo , Pin Jean-Éric , Soler-Escrivà Xaro 
Published: April 2013

Abstract
In a previous paper, the authors have shown that Eilenberg's variety
theorem can be extended to more general structures, called
formations. In this paper, we give a general method to describe the
languages corresponding to saturated formations of groups, which are
widely studied in group theory. We recover in this way a number of
known results about the languages corresponding to the classes of
nilpotent groups, soluble groups and supersoluble groups. Our method
also applies to new examples, like the class of groups having a
Sylow tower.
Improvement of eigenfunction estimates on manifolds of nonpositive curvature
Authors: Hassell Andrew , Tacy Melissa 
Published: April 2013

Abstract
Let (M,g) be a compact, boundaryless manifold of dimension n with the property that either (i) n = 2 and (M,g) has no conjugate points, or (ii) the sectional curvatures of (M,g) are nonpositive. Let Δ be the positive Laplacian on M determined by g. We study the L
2 → Lp
mapping properties of a spectral cluster of (Δ)1/2 of width 1/log λ. Under the geometric assumptions above, Bérard [Math. Z. 155 (1977), 249–276] obtained a logarithmic improvement for the remainder term of the eigenvalue counting function which directly leads to a (log λ)1/2 improvement for Hörmander's estimate on the L
∞ norms of eigenfunctions. In this paper we extend this improvement to the Lp
estimates for all p > 2(n+1)/(n-1).
Synthesis of thiazolo[4,5-e][1,2,4]triazolo[1,5-c]pyrimidine derivatives
Authors: Lee Hyuck Joo , Kim Sung Min , Song Yang-Heon 
Published: April 2013

Abstract
Synthesis of a series of 8-phenylthiazolo[4,5-e][1,2,4]triazolo[1,5-c]pyrimidin-5(4H)-one and 5-piperazino-8-phenylthiazolo[4,5-e][1,2,4]triazolo[1,5-c]pyrmidine compounds with promising biological activity is described.
Flatwise Young’s modulus and flatwise shear modulus of plywood measured by flexural vibration test
Authors: Yoshihara Hiroshi 
Published: April 2013

Abstract
The flatwise Young’s modulus and the flatwise shear modulus of 3-, 5-, and 7-ply plywoods made of Lauan (Shorea sp.) veneers have been determined by conducting flexural vibration tests with various specimen lengths and by finite element analysis. The results indicate that the flatwise Young’s modulus decreases with decreasing specimen length, whereas the opposite is true for the flatwise shear modulus.
The role of Donnan effect in kraft cooking liquor impregnation and hot water extraction of wood
Authors: Kuitunen Susanna , Vuorinen Tapani , Alopaeus Ville 
Published: April 2013

Abstract
In this article, a phenomenological model is proposed for alkali impregnation and hot water extraction of wood. Elementary reaction kinetics, ion exchange (IE) equilibrium, and mass transfer rates are considered in the model. IE is a consequence of the dissociation of the covalently bound uronic acid and phenolic groups in the wood fiber wall (FW). Due to this effect, the molality of cations is higher in the FW liquid than in the liquid external to the FW, whereas the opposite is true for anions. For the development of kinetic models under the participation of hydroxyl and hydrogen ions, the estimation of their molalities in these two liquid phases is crucial because of their ubiquitous presence in chemical reactions. This study applies a recently developed physicochemical modeling environment in which alkali impregnation and hot water extraction processes are considered. The simulations revealed that the IE effect is significant and affects the chemical reaction kinetics in both processes in focus. Furthermore, the IE effect does not remain constant but varies as a function of treatment time.
The antiporter-like subunit constituent of the universal adaptor of complex I, group 4 membrane-bound [NiFe]-hydrogenases and related complexes
Authors: Batista Ana P. , Marreiros Bruno C. , Pereira Manuela M. 
Published: April 2013

Abstract
We have recently investigated the long-recognized relationship between complex I and group 4 [NiFe] hydrogenases and we have established the so-called Energy-converting hydrogenase related (Ehr) complex as a new member of the family. We have also observed that four subunits, homologues to NuoB, D, H and L, are common to the members of the family. We have designated this common group of subunits the universal adaptor. Taking into account the similarity of the Na+/H+ antiporter-like subunits of complex I (NuoL, NuoM and NuoN) and the unique structural characteristic of the long amphipathic α helix part of NuoL, the nature of the antiporter-like subunit of the universal adaptor was questioned. Thus, in this work we further explore the properties of the universal adaptor, investigating which antiporter-like subunit is part of the universal adaptor. We observe that the universal adaptor contains an antiporter-like subunit with a long amphipathic α helix, similar to NuoL. Consequently, the long helix is a common denominator that has been conserved in all members of the family. Such conservation surely reflects the key role of such helix in the energy transduction mechanism of this family of enzymes.
Activity of Lead in Copper Matte at Very Low Lead Concentration
Authors: Tran Ty , Wright Steven , Sun Shouyi 
Published: April 2013

AbstractThe thermodynamic behavior of lead in Cu-Fe matte was investigated using a transportation technique where argon gas was bubbled into a bath of copper matte containing approximately 100 ppm lead at temperatures between 1300 and 1400 °C. The effect of flow rate, temperature and matte grade were investigated on the lead transport from a bath containing 100 grams of synthetic copper matte to the gas phase. The concentration of lead in the bath was followed with time. At argon flow rates between 3 l h1 and 18 l h−1, it was observed that the concentration change of lead in the matte was found to follow a first order relationship where the calculated concentration at time t, is of the form [Pb] = a.e−b.t, where a is equal to the initial lead content in ppm, [Pb]i, and b is an exponential term and t is time in minutes. The partial pressure of lead species in the gas phase was calculated from the concentration changes in the matte and from the bubbling gas rate. At gas flow rates between 3 and 9 l h−1, the lead removal appeared to be under equilibrium conditions. At higher gas flow rates, the apparent rate decreased, mainly due to splashing of matte into the cold zone of the furnace. In these experiments with Ar as the carrier gas, the sulphur and oxygen partial pressures of the melt were not controlled. Chemical analysis of the major components in the matte showed only random variation with bubbling time, and so a thermodynamic solution model for copper matte was used to calculate the equilibrium sulphur pressure expected. From this approach the proportion of Pb, PbS and Pb2 species in the gas could be calculated knowing the relevant reaction constants, e.g., PbS(g) = Pb(g) + ½S2(g). From the proportions of the lead species in the gas, the value of the lead activity coefficient with respect to the gas state could be determined. For a 50% copper matte, it was found that the activity coefficient increased with temperature, from a value of 0.8 at 1300 °C to 1.4 at 1400 °C. At the white metal composition, this value was 0.28 at 1300 °C. These results are compared with other relevant studies in the literature.
Modeling Activity and Interaction Coefficients of Components of Multicomponent Alloy Melts: An Example of Iron Melt
Authors: Zhang Ning , Chen Weiliang , Chen Xingqiu , Ding Xueyong , Zhou Guozhi 
Published: April 2013

AbstractAs a popular thermodynamic calculation method for binary alloys, Miedema's model has been applied in many fields. Chou's Model, a new generation of geometric model for ternary and multicomponent alloy systems, overcomes the intrinsic theoretical defects (including symmetric and asymmetric) existing in some original geometric models. Here, by means of combining Miedema's model and Chou's model as well as including the consideration of the excess entropy we attempted to build the new thermodynamic model to evaluate thermodynamic properties of ternary and multicomponent alloying systems in terms of the physical parameters (molar volume, electronegativity, electronic density and melting point) of constituents. Moreover, the activity and interaction coefficients of a wide of components in iron melt have been discussed in details.
Effect of Ultrasonic Melt Treatment on Solidification Structure of Fe-36Ni Invar Alloy
Authors: Peng Hong-bing , Chen Wei-qing , Yu Yan-chong , Zheng Hong-guang 
Published: April 2013

AbstractThe effect of ultrasonic treatment on the solidification structure of Fe-36Ni invar alloy was investigated. The experiment results showed that the ultrasonic treatment before its solidification had no significant effect on the solidification structure. However, when ultrasonic was inputted into the molten alloy during its solidification process, the primary dendrites were broken up into lots of fragments and solidification structure was refined significantly. When ultrasonic treatment was applied in the melt doped with yttrium before its solidification, ultrasonic cavitation could break up precipitates into many small ones, which could refine its solidification structure as nucleation cores. In samples containing yttrium treated by ultrasonic at 1753 K, the number of the precipitates was 623/mm2 and its average size was 2.18 µm; while at 1803 K, they were 604/mm2 and 2.34 µm respectively. The ultrasonic cavitation had a similar effect at two different temperatures. The solidification structure refined greatly at 1753 K was due to its low pouring temperature.
High Temperature and Organosoluble Poly(amide-imide)s Based on 1,4-Bis[4-aminophenoxy]butane and Aromatic Diacids by Direct Polycondensation: Synthesis and Properties
Authors: Faghihi Khalil , Ashouri Mostafa , Hajibeygi Mohsen 
Published: April 2013

AbstractA series of high temperature and organosoluble poly(amide-imide)s 8a–g were prepared by direct polycondensation from 1,4-bis[4-aminophenoxy]butane 4 and various aromatic diacids 7a–g in a medium consisting of N-methyl-2-pyrrolidone (NMP)/triphenyl phosphite (TPP)/calcium chloride (CaCl2)/pyridine system. Aromatic diacids 7a–g were synthesized by reaction of 3,3′,4,4′-benzophenone tetra carboxylic dianhydride 5 and various amino acids 6a–g. All of the above polymers were fully characterized by 1H-NMR and FT-IR spectroscopy, inherent viscosity, solubility test and thermogravimetric analysis (TGA). The resulted polyamides (PAs) 8a–g have showed admirable good inherent viscosities, thermal stability and solubility.
Developmental issues of university students in Hong Kong
Authors: Shek Daniel T.L. , Cheung Boris P.M. 
Published: April 2013

Abstract
Four domains of developmental issues of university students in Hong Kong are examined in this paper. First, behavioral and lifestyle problems of university students are identified, including alcohol consumption, Internet addiction, cyber-pornography, irregular sleep patterns, and interpersonal violence. Second, the mental health problems of university students, including suicidal ideation, depression and anxiety problems, are outlined. Third, issues on self-determination (including establishment of personal goals), self-confidence, and materialism of the students are reviewed. Fourth, issues related to students’ connection to the society, including egocentrism and civic engagement, are discussed. The views of employers about university graduates in Hong Kong are also examined. With the emergence of developmental issues among Hong Kong university students, it is argued that promoting the psychosocial competencies of university students via positive youth development programs is an important strategy in addressing such issues.
Development of a credit-bearing service leadership subject for university students in Hong Kong
Authors: Shek Daniel T.L. , Yu Lu , Ma Cecilia M.S. , Sun Rachel C.F. , Liu Ting Ting 
Published: April 2013

Abstract
Given that service industries contribute to 93% of Hong Kong’s GDP, an important question that should be asked is whether the education system can promote the development of service leadership among young people in Hong Kong. Unfortunately, service leadership programs specifically designed for university students are lacking in Hong Kong. In this paper, the basic tenets of the Service Leadership and Management framework are presented. Based on the fundamental postulation that effective service leadership is a function of moral character, competence and care (E=MC2), a subject called “Service Leadership” has recently been developed at The Hong Kong Polytechnic University. This paper outlines the objectives, intended learning outcomes, syllabus, assessment, and references of the subject. The proposed evaluation strategies are also described.
Second piloting of a leadership and intrapersonal development subject at The Hong Kong Polytechnic University
Authors: Shek Daniel T.L. , Sun Rachel C.F. , Yuen Walter W.H. , Chui Yat Hung , Dorcas Allen , Ma Cecilia M.S. , Yu Lu , Chak Yammy L.Y. , Law Moon Y.M. , Chung Yida Y.H. , Tsui Pik Fong 
Published: April 2013

Abstract
At The Hong Kong Polytechnic University, a course subject entitled “Tomorrow’s Leaders,” which focuses on positive youth development constructs, was developed for the students admitted under the New Undergraduate Curriculum in the 2012/13 academic year. It fulfills the requirement of “Leadership and Intrapersonal Development” under the General University Requirements. The subject was first piloted in the 2010/11 academic year with very positive evaluation results. To refine the subject and to accumulate more experience, the subject was offered again in the first term of 2011/12 academic year. The course content, evaluation strategies, and some initial findings based on the second piloting exercise are presented in this paper. Consistent with the first piloting exercise, evaluation findings based on different strategies generally showed that the subject promoted the holistic development of the enrolled students.
Effect of Different Particle Sizes and Levels of Wheat Bran on the Physical and Nutritional Quality of Sponge Cake
Authors: Majzoobi Mahsa , Pashangeh Safora , Farahnaky Asgar 
Published: April 2013

Abstract
To increase the dietary fiber of sponge cake, it was enriched with wheat bran of different levels (0, 5, 10, 15, and 20%, w/w; flour basis) and particle sizes (90, 170, 280, and 420 μm). The results showed that both crude fiber and phytic acid contents of the bran decreased with the reduction in the particle size. Batter density increased whereas batter consistency decreased with increase in the particle size and the level of the bran. The crust and crumb color became darker, more reddish and less yellowish as the level and particle size of the bran increased. Density of the cakes decreased as higher percentages and coarser brans were included. Determination of the textural properties of the cakes using texture profile analysis technique showed that with increase in the percentage of wheat bran, hardness, gumminess, and chewiness increased whereas, cohesiveness and springiness decreased. According to the taste panel, using no more than 10% bran with particle size smaller than 170 μm resulted in cakes similar to the control. The total dietary fiber and phytic acid content of the resultant cakes was 5.95% and 2.90 (mg/g), respectively.