bluuebunny/crossref_metadata_2025_split huggingface dataset:
Lactation and appetite-regulating hormones: increased maternal plasma peptide YY concentrations 3–6 months postpartum
Authors: Vila Greisa , Hopfgartner Judith , Grimm Gabriele , Baumgartner-Parzer Sabina M. , Kautzky-Willer Alexandra , Clodi Martin , Luger Anton 
Published: August 2015

AbstractBreast-feeding is associated with maternal hormonal and metabolic changes ensuring adequate milk production. In this study, we investigate the impact of breast-feeding on the profile of changes in maternal appetite-regulating hormones 3–6 months postpartum. Study participants were age- and BMI-matched lactating mothers (n 10), non-lactating mothers (n 9) and women without any history of pregnancy or breast-feeding in the previous 12 months (control group, n 10). During study sessions, young mothers breast-fed or bottle-fed their babies, and maternal blood samples were collected at five time points during 90 min: before, during and after feeding the babies. Outcome parameters were plasma concentrations of ghrelin, peptide YY (PYY), leptin, adiponectin, prolactin, cortisol, insulin, glucose and lipid values. At baseline, circulating PYY concentrations were significantly increased in lactating mothers (100·3 (se 6·7) pg/ml) v. non-lactating mothers (73·6 (se 4·9) pg/ml, P=0·008) and v. the control group (70·2 (se 9) pg/ml, P=0·021). We found no differences in ghrelin, leptin and adiponectin values. Baseline prolactin concentrations were over 4-fold higher in lactating mothers (P<0·001). Lactating women had reduced TAG levels and LDL-cholesterol:HDL-cholesterol ratio, but increased waist circumference, when compared with non-lactating women. Breast-feeding sessions further elevated circulating prolactin (P<0·001), but induced no acute effects on appetite-regulating hormones. In summary, one single breast-feeding session did not acutely modulate circulating appetite-regulating hormones, but increased baseline PYY concentrations are associated with prolonged lactation. PYY might play a role in the coordination of energy balance during lactation, increasing fat mobilisation from maternal depots and ensuring adequate milk production for the demands of the growing infant.
Administration of Lactobacillus gasseri SBT2055 suppresses macrophage infiltration into adipose tissue in diet-induced obese mice
Authors: Ukibe Ken , Miyoshi Masaya , Kadooka Yukio 
Published: August 2015

AbstractAdministration of Lactobacillus gasseri SBT2055 (LG2055) has been shown to prevent body weight gain and it also down-regulates the expression of the Ccl2 gene in adipose tissue in diet-induced obese mice. The CC chemokine ligand 2 has a crucial role in macrophage infiltration into adipose tissue, which is known to exacerbate inflammation. However, it is not yet known how LG2055 affects the invasion of macrophages into adipose tissue. C57BL/6J male mice were fed a normal-fat diet (10 % energy fat), high-fat diet (HFD; 45 % energy fat), or HFD containing LG2055 for 12 weeks. After the feeding period, gene expression and macrophage population in adipose tissue were analysed by real-time PCR and flow cytometry, respectively. Body weight and abdominal fat weight were not altered by feeding LG2055. Flow cytometry analysis revealed that the population of macrophages in adipose tissue was significantly reduced by feeding LG2055 compared with HFD only. Furthermore, the ratio of classically activated inflammatory macrophages (M1 macrophages) to total macrophages was significantly decreased in the LG2055-fed group. The expressions of Ccl2, Ccr2 and Lep were down-regulated and that of Il6, Tnf and Nos2 tended to be down-regulated in adipose tissue by feeding LG2055. In addition, fasting glucose levels were significantly decreased in the LG2055-fed group. These data suggest that administration of LG2055 might attenuate inflammation, which is caused by the intake of an HFD, through the inhibition of macrophage invasion into adipose tissue.
CUSTODY CHAINS AND ASSET VALUES: WHY CRYPTO-SECURITIES ARE WORTH CONTEMPLATING
Authors: Micheler Eva 
Published: August 2015

AbstractComputerisation facilitates instantaneous and direct links between all of us in our work and social lives. At the same time, and counter-intuitively so, securities are increasingly held indirectly through chains of custodians that operate between issuers and investors. This disconnects investors from issuers and can significantly reduce the value of assets. The regulatory framework does not prevent this effect. UK-regulated holders of client securities should be required to hold these directly in the name of the investor. At an international level, it is worth asking whether the technology underlying bitcoin and other cryptocurrencies can be used to create an un-intermediated securities ledger connecting investors and issuers directly.
THE ENFORCEABILITY OF ARBITRATION CLAUSES IN TRUSTS
Authors: Conaglen Matthew 
Published: August 2015

AbstractThis article considers the enforceability of arbitration clauses which are included in trust documentation. It focuses on two main questions. The first is whether internal trust disputes are capable of being settled by arbitration. The article offers arguments in favour of the arbitrability of such disputes. It then addresses the question of whether parties to an internal trust dispute can be forced to arbitrate, rather than litigate, where the trust documentation contains an arbitration clause. It is argued that there are real difficulties in the argument that such clauses can be enforced as arbitration agreements, under the ordinary arbitration statutes, but that the court could potentially enforce such a clause under its inherent jurisdiction to control its proceedings.
The Politics of Language Roadmaps in Canada: Understanding the Conservative Government's Approach to Official Languages
Authors: Cardinal Linda , Gaspard Helaina , Léger Rémi 
Published: August 2015

AbstractThis article critically examines the Conservative government's approach to official languages, through a policy instrument framework. Special attention is paid to the third federal roadmap for official languages—the first having been unveiled by the Liberal government in 2003 and the second by the Conservative minority government in 2008—and how this roadmap conveys a new representation of official languages in relation to Canadian identity and citizenship. The focus on the linguistic integration of new immigrants in the 2013 language roadmap generates interest. The policy instrument framework also shows how language roadmaps represent the fourth generation of official language policies in Canada; the first three generations found their respective bases in the 1969Official Languages Act, theCharter of Rights and Freedomsand the 1988Official Languages Act. The article concludes that an analysis of language roadmaps elucidates transformations initiated by the Conservative governments in the area of official languages in Canada. It also promotes further exploration and analysis of language policies through the policy instrument framework.
STATE AND DIPLOMATIC IMMUNITY AND EMPLOYMENT RIGHTS: EUROPEAN LAW TO THE RESCUE?
Authors: Garnett Richard 
Published: August 2015

AbstractThe issues of State and diplomatic immunity in cases involving persons employed by foreign States in embassies or consulates or engaged directly by diplomats remain controversial. The focus of this article is on recent developments in European law, in particular under the European Convention on Human Rights, the Brussels I Regulation and the Charter of the European Union, the effect of which has been to enhance the rights of employees of foreign States. Analysis is also made of the United Nations Convention on Jurisdictional Immunities of States and their Property and the current domestic practice of States with the aim of identifying the present international law standard on State immunity and embassy and consular employment. Employees of diplomats, however, remain inadequately protected and this article considers possible strategies for improving their position.
Finding potential high-yield areas for Mexican maize under current and climate change conditions
Authors: URETA C. , MARTÍNEZ-MEYER E. , GONZÁLEZ E. J. , ÁLVAREZ-BUYLLA E. R. 
Published: August 2015

SUMMARYAnalyses of the geographic patterns of wild species abundance have been carried out in studies ranging from those interested in hot-spots for biodiversity and conservation to basic ecological analyses. Based on the methodological approaches used, the present study searched for areas of higher yield among native races of maize in Mexico, its centre of origin and diversification. Ecological theory suggests that population fitness, and thus abundance, is maximal at the centroid of the multi-dimensional ecological niche of a particular species, and decreases progressively as distance from it increases. In the present study, yield was used instead of abundance, assuming it to be higher under optimal environmental conditions. It was assessed whether nine Mexican maize races exhibited higher yields in areas that are ecologically closer to their niche centroid (NC), or a niche optimum (NO) that did not always coincide with the geometric centroid. Environmental and geographical clusters for each race were also created to identify additional NOs in widely distributed races. All races showed significant correlations between yield and distance, both to the NC or NOs, but in only six of them was the chosen model better than the null model. Three races and two sub-groups were selected for projection under climate change conditions: Celaya (R2= 0·288), Celaya 3 (R2= 0·774), Vandeño (R2= 0·277) and Vandeño 2 (R2= 0·466) and Tepecintle (R2= 0·537). The Celaya race improved with environmental clustering, while Vandeño improved under geographical clustering. Finally, Tepecintle was projected at a race level. Projections under climate change suggested some potential areas for high yields in the future. It was concluded that the approach used in the present paper, considering the distance to NC/NO as a predictor of maize landrace yield, may contribute important information to agro-ecological projects.
Serological and coprological analyses for the diagnosis of Fasciolagigantica infections in bovine hosts from Sargodha, Pakistan
Authors: Rehman T. , Khan M.N. , Abbas R.Z. , Babar W. , Sikandar A. , Zaman M.A. 
Published: August 2015

AbstractA serological and coprological survey of fasciolosis was conducted in bovine hosts from the Sargodha district, Pakistan using excretory–secretory (ES) antigens of Fasciola gigantica from cattle and buffaloes. Livers, faecal and blood samples of 146 cattle and 184 buffaloes were collected from slaughterhouses and examined for the presence of any Fasciola in bile ducts and ova in faeces. Serum was separated. ES antigens were prepared by incubating adult Fasciola in phosphate-buffered saline for 6–8 h and then filtering using a 0.22-μm syringe filter. Checkerboard titration was performed and optimum concentrations of antigen and serum were determined. Sero-prevalence was found to be 50.00 and 38.35% in buffalo and cattle, respectively. Using liver examination as the gold standard, enzyme-linked immunosorbent assay (ELISA) sensitivity was found to be 100% in both buffalo and cattle as compared with that of coprological examination in buffalo (61.79%) and cattle (54.54%). This indigenous ELISA was also highly specific, with values of 96.84 and 98.90% in buffalo and cattle, respectively. Positive predictive values were calculated as 96.74 and 98.21% in buffalo and cattle, respectively, while negative predictive values were 100%. For the validation of indigenous ELISA in field surveys, faecal and blood samples were collected from six sub-districts (tehsils) in the district of Sargodha. Sera were screened for the presence of anti-fasciola antibodies using both the indigenous and commercial ELISA kits. While both kits were equally sensitive, the indigenous ELISA was found to be more specific. The highest prevalence of fasciolosis was found in December, as ascertained using both serological and coprological examination. Significant differences were found in prevalences of fasciolosis in different sub-districts and age groups, together with feeding and watering systems.
Exploring linguistic malleability across the life span: Age-specific patterns in quotative use
Authors: Buchstaller Isabelle 
Published: August 2015

AbstractThis article explores the degree and kind of lability that occurs throughout the life span of the individual during ongoing rapid change in the quotative system. Two comparative analyses trace speakers' use ofbe likeacross a shorter and a longer time span. Trend data reveal that the robust change is arrested in the middle age brackets; speakers in their thirties seem to display ‘retrograde movement’ (Sankoff & Wagner 2006) away from the community-wide change. This finding could be interpreted as incipient age-grading. A small-scale panel sample collected forty-two years after the initial interview suggests that some older speakers participate in the trend, albeit at very low frequencies. This finding, while exploratory at the moment, might be interpreted as indicative of ‘life-span change’ (Sankoff 2005). A conception of the change in progress in the quotative system as monotonous would thus both under and overestimate the rate of change. (Change across the life span, age-grading, retrograde change, life-span change, quotation, style, language ideologies)*
‘New’ Scottish Gaelic speakers in Glasgow: A phonetic study of language revitalisation
Authors: Nance Claire 
Published: August 2015

AbstractThis article analyses phonetic variation among young people who have learned a minority language in immersion schooling as part of revitalisation measures. Such speakers are increasingly referred to as ‘new speakers’ in an expanding body of literature. The variable phonetic features analysed are vowels, laterals, and intonation in the speech of new Gaelic speakers from Glasgow and the Isle of Lewis. Results support previous work suggesting that new speakers will sound different from ‘traditional speakers’. These results are discussed in terms of language contact, modes of acquisition in revitalisation situations, and the differing perceptions and ideologies surrounding how new speakers use Gaelic. The data also necessitate an examination of some of the assumptions in sociolinguistic models of change and their applicability to contexts of rapid social evolution. (New speakers, language revitalisation, minority languages, Scottish Gaelic, laterals, vowels, intonation)*
The perlocutionary is political: Listening as self-determination in a Papua New Guinean polity
Authors: Slotta James 
Published: August 2015

AbstractJ. L. Austin's influential dissection of speech acts into locutionary, illocutionary, and perlocutionary acts has given rise to much scholarly attention to illocutionary acts and forces. While the perlocutionary facet of speech acts has gone largely undiscussed by philosophers and linguists, folk theories of language often attend closely to the relation between speech and its consequences. In this article, I discuss one conception of perlocutions prominent in Yopno speaking communities in Papua New Guinea that emphasizes the agentive role of listeners in mediating between speech and its outcome. This cultural conception of perlocutions, I argue, is tied to a political sensibility that stresses the self-determination and equality of adult men. The article shows how cultural conceptions of perlocutions provide insight into political values and practices, and how political concerns inform folk models of perlocutions. (Perlocutions, politics, fashions of speaking, language ideology, Melanesia, Papua New Guinea)*
Motivating rural older residents to prepare for disasters: moving beyond personal benefits
Authors: ASHIDA SATO , ROBINSON ERIN L. , GAY JANE , RAMIREZ MARIZEN 
Published: August 2015

ABSTRACTIn the United States of America (USA), older adults in rural areas are at increased risk for adverse outcomes of disasters, partly due to medical needs, limited or long geographic distances from community resources, and less knowledge and motivation about preparedness steps. Older residents and ageing service providers in a rural community in the USA were interviewed regarding their perceptions about disasters and preparedness, and their reactions to the preparedness training programme using the concepts of the Extended Parallel Process Model. Participants generally indicated low motivation to engage in preparedness behaviours despite perceptions of personal risk and beliefs that preparedness behaviours were easy and could improve disaster outcomes. A theme of social relationships emerged from the data, with participants identifying social relationships as resources, barriers and motivators. People surrounding older adults can support or deter their preparedness behaviours, and sometimes elicit a desire to protect the wellbeing of others. Findings suggest two potential strategies to facilitate preparedness behaviours by moving beyond personal benefits: highlighting older adults' increased ability to protect the wellbeing of younger generations and their community by being prepared themselves, and engaging family, friends and neighbours in preparedness programmes to enhance the resilience of their social groups. Older adults in many cultures have a desire to contribute to their society. Novel and effective approaches to increase preparedness could target their social groups.
Input and uptake at 7 months predicts toddler vocabulary: the role of child-directed speech and infant processing skills in language development
Authors: NEWMAN ROCHELLE S. , ROWE MEREDITH L. , BERNSTEIN RATNER NAN 
Published: August 2015

ABSTRACTBoth the input directed to the child, and the child's ability to process that input, are likely to impact the child's language acquisition. We explore how these factors inter-relate by tracking the relationships among: (a) lexical properties of maternal child-directed speech to prelinguistic (7-month-old) infants (N = 121); (b) these infants' abilities to segment lexical targets from conversational child-directed utterances in an experimental paradigm; and (c) the children's vocabulary outcomes at age 2;0. Both repetitiveness in maternal input and the child's speech segmentation skills at age 0;7 predicted language outcomes at 2;0; moreover, while these factors were somewhat inter-related, they each had independent effects on toddler vocabulary skill, and there was no interaction between the two.
Global blow-up for a semilinear heat equation on a subspace
Authors: Budd C. J. , Dold J. W. , Galaktionov V. A. 
Published: August 2015

We study the asymptotic behaviour as t → T–, near a finite blow-up time T > 0, of decreasing-in-x solutions to the following semilinear heat equation with a non-local term:with Neumann boundary conditions and strictly decreasing initial function u0(x) with zero mass. We prove sharp estimates for u(x, t) as t → T–, revealing a non-uniform global blow-up:uniformly on any compact set [δ, 1], δ ∈ (0, 1).
Families, Intergenerational Bonds, and Aging in Sub-Saharan Africa
Authors: Aboderin Isabella , Hoffman Jaco 
Published: August 2015

RÉSUMÉCette note de recherche propose une justification, et offre un ensemble de paramètres initiaux, pour un effort explicite de forger une politique et une gérontologie de famille scientifiquement pertinentes à l'Afrique. Il se fonde sur une évaluation critique des discours politiques dominants dans la région et les efforts de recherche existants concernant les familles et le vieillissement, en particulier en Afrique sub-saharienne (ASS).
Intra-couple Caregiving of Older Adults Living Apart Together: Commitment and Independence
Authors: De Jong Gierveld Jenny 
Published: August 2015

RÉSUMÉRécemment, un nombre accroîssant d’adultes d’âge mûr ou plus agés se lancent dans des relations de “vivre ensemble séparément” après le divorce ou pendant le veuvage. Un "VES" est une relation intime dans laquelle les partenaires maintiennent domiciles séparées. Cette étude a examiné les types de soins pour les couples VES plus âgés et à long terme, et a dévoilé des commentaires personnels au sujet des soins pour ces couples. Nous avons interrogé 25 VES partenaires et aussi avons interrogé un groupe de comparaison de 17 personnes âgées qui se sont remariées dans les Pays-Bas, à travers une étude ancillaire à la Panel Study Pays-Bas parenté (PSP-BP). Les résultats ont révelé qu’environ la moitié de ces partenaires VES a l’intention d’ échanger des soins si nécessaire (engagement du partenariat); l’autre moitié a éprouvé des sentiments ambigus, ou avait l’intention de refuser des soins (l’orientation indépendante). Toutefois, pour les partenaires VES déjà confrontés aux maladies dans leur relation actuelle, tous ont soigné partenaires dans leur besoin. La minorité de partenaires VES qui ne voulait pas échanger réciproquement les soins sont plus susceptibles de donner, plutôt que de recevoir, des soins.
Long-term mortality of hospitalized pneumonia in the EPIC-Norfolk cohort
Authors: MYINT P. K. , HAWKINS K. R. , CLARK A. B. , LUBEN R. N. , WAREHAM N. J. , KHAW K.-T. , WILSON A. M. 
Published: August 2015

SUMMARYLittle is known about cause-specific long-term mortality beyond 30 days in pneumonia. We aimed to compare the mortality of patients with hospitalized pneumonia compared to age- and sex-matched controls beyond 30 days. Participants were drawn from the European Prospective Investigation into Cancer (EPIC)-Norfolk prospective population study. Hospitalized pneumonia cases were identified from record linkage (ICD-10: J12-J18). For this study we excluded people with hospitalized pneumonia who died within 30 days. Each case identified was matched to four controls and followed up until the end June 2012 (total 15 074 person-years, mean 6·1 years, range 0·08–15·2 years). Cox regression models were constructed to examine the all-cause, respiratory and cardiovascular mortality using date of pneumonia onset as baseline with binary pneumonia status as exposure. A total of 2465 men and women (503 cases, 1962 controls) [mean age (s.d.) 64·5 (8·3) years] were included in the study. Between a 30-day to 1-year period, hazard ratios (HRs) of all-cause and cardiovascular mortality were 7·3 [95% confidence interval (CI) 5·4–9·9] and 5·9 (95% CI 3·5–9·7), respectively (with very few respiratory deaths within the same period) in cases compared to controls after adjusting for age, sex, asthma, smoking status, pack years, systolic and diastolic blood pressure, diabetes, physical activity, waist-to-hip ratio, prevalent cardiovascular and respiratory diseases. All outcomes assessed also showed increased risk of death in cases compared to controls after 1 year; respiratory cause of death being the most significant during that period (HR 16·4, 95% CI 8·9–30·1). Hospitalized pneumonia was associated with increased all-cause and specific-cause mortality beyond 30 days.