bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tunable blue-green-emitting wurtzite ZnS:Mg nanosheet-assembled hierarchical spheres for near-UV white LEDs
Authors: Reddy Devulapalli Amaranatha , Kim Deok Hyeon , Rhee Seuk Joo , Lee Bo Wha , Liu Chunli 
Published: January 2014

Abstract
Mg-doped ZnS hierarchical spheres have been synthesized via hydrothermal method using mixed solvents of ethylenediamine and DI water without any surface-active agent. The surface morphology and microstructure studies revealed that the hierarchical spheres were consisted of many well-aligned nanosheets with width 10 nm and length about 50 ~ 100 nm. X-Ray diffraction results show that the ZnS:Mg hierarchical spheres have wurtzite structure with high crystallinity. The absorption edge in the diffuse reflection spectra shifts towards lower wavelength with increasing Mg concentration, indicating an expansion in the bandgap energy that is estimated to be in the range of 3.28 to 3.47 eV. Blue-green photoluminescence with tunable intensity and peak position was observed depending on the Mg content. The Mg2+-activated ZnS phosphor can be good candidates for blue-green components in near-UV white light-emitting diodes.
Estimation of sexual behavior in the 18-to-24-years-old Iranian youth based on a crosswise model study
Authors: Vakilian Katayon , Mousavi Seyed Abbas , Keramat Afsaneh 
Published: January 2014

Abstract

Background
In many countries, negative social attitude towards sensitive issues such as sexual behavior has resulted in false and invalid data concerning this issue.
This is an analytical cross-sectional study, in which a total number of 1500 single students from universities of Shahroud City were sampled using a multi stage technique. The students were assured that their information disclosed for the researcher will be treated as private and confidential. The results were analyzed using crosswise model, Crosswise Regression, T-test and Chi-square tests.

Findings
It seems that the prevalence of sexual behavior among Iranian youth is 41% (CI = 36-53).

Conclusion
Findings showed that estimation sexual relationship in Iranian single youth is high. Thus, devising training models according to the Islamic-Iranian culture is necessary in order to prevent risky sexual behavior.
Fast selection of miRNA candidates based on large-scale pre-computed MFE sets of randomized sequences
Authors: Warris Sven , Boymans Sander , Muiser Iwe , Noback Michiel , Krijnen Wim , Nap Jan-Peter 
Published: January 2014

AbstractBackgroundSmall RNAs are important regulators of genome function, yet their prediction in genomes is still a major computational challenge. Statistical analyses of pre-miRNA sequences indicated that their 2D structure tends to have a minimal free energy (MFE) significantly lower than MFE values of equivalently randomized sequences with the same nucleotide composition, in contrast to other classes of non-coding RNA. The computation of many MFEs is, however, too intensive to allow for genome-wide screenings.ResultsUsing a local grid infrastructure, MFE distributions of random sequences were pre-calculated on a large scale. These distributions follow a normal distribution and can be used to determine the MFE distribution for any given sequence composition by interpolation. It allows on-the-fly calculation of the normal distribution for any candidate sequence composition.ConclusionThe speedup achieved makes genome-wide screening with this characteristic of a pre-miRNA sequence practical. Although this particular property alone will not be able to distinguish miRNAs from other sequences sufficiently discriminative, the MFE-based P-value should be added to the parameters of choice to be included in the selection of potential miRNA candidates for experimental verification.
Comparative analysis of the activation of unfolded protein response by spike proteins of severe acute respiratory syndrome coronavirus and human coronavirus HKU1
Authors: Siu Kam-Leung , Chan Ching-Ping , Kok Kin-Hang , C-Y Woo Patrick , Jin Dong-Yan 
Published: January 2014

Abstract

Background
Whereas severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) is associated with severe disease, human coronavirus HKU1 (HCoV-HKU1) commonly circulates in the human populations causing generally milder illness. Spike (S) protein of SARS-CoV activates the unfolded protein response (UPR). It is not understood whether HCoV-HKU1 S protein has similar activity. In addition, the UPR-activating domain in SARS-CoV S protein remains to be identified.

Results
In this study we compared S proteins of SARS-CoV and HCoV-HKU1 for their ability to activate the UPR. Both S proteins were found in the endoplasmic reticulum. Transmembrane serine protease TMPRSS2 catalyzed the cleavage of SARS-CoV S protein, but not the counterpart in HCoV-HKU1. Both S proteins showed a similar pattern of UPR-activating activity. Through PERK kinase they activated the transcription of UPR effector genes such as Grp78, Grp94 and CHOP. N-linked glycosylation was not required for the activation of the UPR by S proteins. S1 subunit of SARS-CoV but not its counterpart in HCoV-HKU1 was capable of activating the UPR. A central region (amino acids 201–400) of SARS-CoV S1 was required for this activity.

Conclusions
SARS-CoV and HCoV-HKU1 S proteins use distinct UPR-activating domains to exert the same modulatory effects on UPR signaling.
Synovial membrane protein expression differs between juvenile idiopathic arthritis subtypes in early disease
Authors: Finnegan Sorcha , Robson Joanne , Scaife Caitriona , McAllister Catherine , Pennington Stephen R , Gibson David S , Rooney Madeleine E 
Published: January 2014

Abstract
Introduction
Juvenile idiopathic arthritis (JIA) is the most common rheumatological disease of childhood with a prevalence of around 1 in 1,000. Without appropriate treatment it can have devastating consequences including permanent disability from joint destruction and growth deformities. Disease aetiology remains unknown. Investigation of disease pathology at the level of the synovial membrane is required if we want to begin to understand the disease at the molecular and biochemical level. The synovial membrane proteome from early disease-stage, treatment naive JIA patients was compared between polyarticular and oligoarticular subgroups.

Methods
Protein was extracted from 15 newly diagnosed, treatment naive JIA synovial membrane biopsies and separated by two dimensional fluorescent difference in-gel electrophoresis. Proteins displaying a two-fold or greater change in expression levels between the two subgroups were identified by matrix assisted laser desorption ionization-time of flight mass spectrometry with expression further verified by Western blotting and immunohistochemistry.

Results
Analysis of variance analysis (P ≤ 0.05) revealed 25 protein spots with a two-fold or greater difference in expression levels between polyarticular and oligoarticular patients. Hierarchical cluster analysis with Pearson ranked correlation revealed two distinctive clusters of proteins. Some of the proteins that were differentially expressed included: integrin alpha 2b (P = 0.04); fibrinogen D fragment (P = 0.005); collagen type VI (P = 0.03); fibrinogen gamma chain (P = 0.05) and peroxiredoxin 2 (P = 0.02). The identified proteins are involved in a number of different processes including platelet activation and the coagulation system.

Conclusions
The data indicate distinct synovial membrane proteome profiles between JIA subgroups at an early stage in the disease process. The identified proteins also provide insight into differentially perturbed pathways which could influence pathological events at the joint level.
HSF1 at a glance
Authors: Vihervaara Anniina , Sistonen Lea 
Published: January 2014

ABSTRACTHeat shock factor 1 (HSF1) is an evolutionarily highly conserved transcription factor that coordinates stress-induced transcription and directs versatile physiological processes in eukaryotes. The central position of HSF1 in cellular homeostasis has been well demonstrated, mainly through its strong effect in transactivating genes that encode heat shock proteins (HSPs). However, recent genome-wide studies have revealed that HSF1 is capable of reprogramming transcription more extensively than previously assumed; it is also involved in a multitude of processes in stressed and non-stressed cells. Consequently, the importance of HSF1 in fundamental physiological events, including metabolism, gametogenesis and aging, has become apparent and its significance in pathologies, such as cancer progression, is now evident. In this Cell Science at a Glance article, we highlight recent advances in the HSF1 field, discuss the organismal control over HSF1, and present the processes that are mediated by HSF1 in the context of cell type, cell-cycle phase, physiological condition and received stimuli.
Investigating the Anisotropic Features of Particle Orientation in Synthetic Swelling Clay Porous Media
Authors: Hubert Fabien , Bihannic Isabelle , Prêt Dimitri , Tertre Emmanuel , Nauleau Benoit , Pelletier Manuel , Demé Bruno , Ferrage Eric 
Published: January 2014

AbstractThe present study investigated the anisotropy in the orientation of particles in synthetic swelling clay media prepared from the sedimentation of particle-sized fractions of vermiculite. The different size fractions (<0.1, 0.1–0.2, 1–2, and 10–20 μm) were chosen because they represent the wide range of particle sizes of swelling clay minerals encountered in natural environments. Small-angle neutron scattering (SANS) and neutron diffraction measurements allowed the characteristic scattering/diffraction features to be derived and the quantitative information about the particle orientation distributions along two directions with respect to the sedimentation plane to be extracted. The results obtained confirmed that the increase in particle size was associated with the development of a random orientation for the particles, whereas the hydration state had a negligible impact on the organization of the porous media. For finer vermiculite particles, the rocking curves demonstrated an anisotropy of the systems that is similar to those reported previously on natural montmorillonite minerals. This result suggests that the location of the layer charge has little or no impact on the anisotropy features of particle orientation. For the coarsest fraction (10–20 μm), quantitative information about the particle orientation revealed that the relative proportion of the isotropic contribution represents up to 85% of the material. The anisotropy in the 2D SANS patterns revealed a pore-network anisotropy that was consistent with the particle size.
Preparation and Characterization of Fe-, Co-, and Ni-Containing Mg-Al-Layered Double Hydroxides
Authors: Curtius Hilde , Kaiser Gabriel , Rozov Konstantin , Neumann Andreas , Dardenne Kathy , Bosbach Dirk 
Published: January 2014

AbstractSyntheses of Fe-, Co-, and Ni-containing Mg-Al-layered double hydroxides (LDHs) are described here because Fe, Co, and Ni represent the major constituents in steel containers used for storing spent nuclear fuel. Much evidence exists for the formation of LDHs during the corrosion of such containers under repository-relevant conditions. Because of their anion-exchange properties, LDHs can be considered as materials with the potential to retain and immobilize anionic radionuclides. Evaluation of the thermodynamic properties of LDHs is essential for reliable prediction of their behavior (solubility, anion exchange properties) in geochemical environments. The impact on the thermodynamic properties of the isostructural incorporation of divalent cations into the LDH was the main focus of the present study.Mg-Al-Cl-LDH and the Fe-, Co-, and Ni-doped LDHs were synthesized by the co-precipitation method and then characterized (using powder X-ray diffraction (PXRD), extended X-ray absorption fine structure (EXAFS), X-ray absorption near edge structure (XANES), Fourier-transform infrared spectroscopy (FTIR), scanning electron microscopy energy-dispersive X-ray spectroscopy (SEM-EDX), and thermogravimetric analyses (TGA)).The PXRD and EXAFS analyses indicated that all synthesized samples were pure LDHs where Co, Ni, and Fe were incorporated isostructurally. The EXAFS and XANES results demonstrated that Ni and Co were incorporated as divalent cations and Fe as a trivalent cation. Thermodynamic calculations were performed assuming an equilibrium state between aqueous solutions and corresponding precipitates after synthesis. The first estimates of the molar Gibbs free energies for Fe-, Co-, and Ni-containing LDHs at 70ºC were provided. The calculated Gibbs free energy of the pure Mg-Al-LDH (-3629 kJ/mol) was slightly less than those for Fe-, Co-, and Ni-containing compositions (-3612±50, -3604±50, -3593±50kJ/mol).
Tracking Fluid Movement During Cyclic Steam Stimulation of Clearwater Formation Oil Sands Using Stable Isotope Variations of Clay Minerals
Authors: McKay Jennifer L. , Longstaffe Frederick J. 
Published: January 2014

AbstractIn situ thermal recovery methods such as cyclic steam stimulation (CSS) are required to extract highly viscous bitumen from the Clearwater Formation oil sands of Alberta, Canada. The injection of hot fluids during CSS has altered the mineralogy of the sands, resulting in the loss of some minerals (e.g. disseminated siderite, volcanic glass) and precipitation of others (e.g. zeolites and abundant hydroxy-interlayered smectite). The high temperatures and high water—rock ratios associated with CSS might also alter the oxygen and hydrogen isotopic compositions of pre-existing clay minerals even in the absence of mineralogical changes. The present study exploits this fact to track the movement of injected hot fluids during CSS. Berthierine, a common diagenetic clay mineral in the Clearwater sands, survived CSS but acquired substantially lower δ18O and δ2H values in cores located ≤ 10 m from the injection well. In contrast, the oxygen and hydrogen isotopic compositions of berthierine in cores located further from the injection well were generally unaffected, except at the depth of steam injection where horizontal fractures facilitate greater lateral penetration of hot fluids. Smectitic clays in near-injector cores also acquired lower δ18O values during CSS, but a systematic shift in δ2H values was not observed. While hydrogen-isotope exchange undoubtedly occurred, the particular combination of temperature and H isotopic composition of the injected fluid used during CSS appears to have yielded post-steam δ2H values that are indistinguishable from pre-steam values. Only samples from near-injector core G-OB3 that contain hydroxy-interlayered smectite have lower δ2H values as a result of CSS.
Vibration Modeling of Arc-Based Cantilevers for Energy Harvesting Applications
Authors: Apo Daniel J. , Sanghadasa Mohan , Priya Shashank 
Published: January 2014

Abstract
Cantilever beams are widely used for designing transducers for low-frequency vibration energy harvesting. However, in order to keep the dimensions within reasonable constraints, a large tip mass is generally required for reducing the resonance frequency below 100 Hz which has adverse effect on the reliability. This study provides a breakthrough toward realizing low-frequency micro-scale transduction structures. An analytical out-of-plane vibration model for standalone arc-based cantilever beams was developed that includes provisions for shear and rotary inertia, multidirectional arcs, and multiple layers. The model was applied to a multilayered cantilever beam (10-mm wide and 0.1-mm thick) composed of three arcs, and the results indicate that the fundamental bending mode of the beam was 38 Hz for a silicon substrate thickness of 100 μm. The model was validated with modal experimental results from an arc-based cantilever made out of aluminum.
Effect of Frying Time and Temperature on the Functional Properties of Carrot Pomace, Pulse Powder and Rice Flour–Based Extrudates
Authors: Dar Aamir Hussain , Sharma Harish Kumar , Kumar Navneet 
Published: January 2014

Abstract
The extrudates prepared under the optimized conditions of flour proportion (rice flour, pulse powder and carrot pomace), moisture content, screw speed and die temperature, were fried at temperatures of 170, 180, 190 and 200°C and for a time of 5, 10 and 15 s. Based on sensory characteristics, the selected product was stored for a period of 6 months in metalized polypropylene and evaluated for free fatty acid, peroxide value, hardness, crispiness, colour and beta carotene. The increase in colour L-values, b-values, oil absorption and decrease in colour a-values in carrot pomace–based rice extrudates was observed with the increase in frying temperature and time. The product obtained at 180°C for 15 s was rated better. The decrease in free fatty acid, colour L-values, b-values, crispiness and beta carotene and increase in peroxide value, hardness and colour a-values in carrot pomace–based rice extrudates was observed with the increase in storage period. However, the quantitative change in attributes suggested the acceptability of the product even after the storage of 6 month.
Complementarity and redundancy of interactions enhance attack rates and spatial stability in host–parasitoid food webs
Authors: Peralta Guadalupe , Frost Carol M. , Rand Tatyana A. , Didham Raphael K. , Tylianakis Jason M. 
Published: January 2014

Complementary resource use and redundancy of species that fulfill the same ecological role are two mechanisms that can respectively increase and stabilize process rates in ecosystems. For example, predator complementarity and redundancy can determine prey consumption rates and their stability, yet few studies take into account the multiple predator species attacking multiple prey at different rates in natural communities. Thus, it remains unclear whether these biodiversity mechanisms are important determinants of consumption in entire predator–prey assemblages, such that food‐web interaction structure determines community‐wide consumption and stability.Here, we use empirical quantitative food webs to study the community‐wide effects of functional complementarity and redundancy of consumers (parasitoids) on herbivore control in temperate forests. We find that complementarity in host resource use by parasitoids was a strong predictor of absolute parasitism rates at the community level and that redundancy in host‐use patterns stabilized community‐wide parasitism rates in space, but not through time. These effects can potentially explain previous contradictory results from predator diversity research. Phylogenetic diversity (measured using taxonomic distance) did not explain functional complementarity or parasitism rates, so could not serve as a surrogate measure for functional complementarity.Our study shows that known mechanisms underpinning predator diversity effects on both functioning and stability can easily be extended to link food webs to ecosystem functioning.
Serum C‐Reactive Protein and Immunoglobulin G Antibodies to Periodontal Pathogens May Be Effect Modifiers of Periodontitis and Hyperglycemia
Authors: Choi Youn‐Hee , McKeown Robert E. , Mayer‐Davis Elizabeth J. , Liese Angela D. , Song Keun‐Bae , Merchant Anwar T. 
Published: January 2014

Background: Serum C‐reactive protein (CRP) is elevated in both periodontitis and type 2 diabetes mellitus through inflammation. Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis have been found in periodontal pockets in patients with diabetes. This study examines effect modification by examining the extent to which the associations between periodontitis and hyperglycemia were different by levels of serum CRP and periodontal pathogens.Methods: Blood samples with plasma were evaluated for immunoglobulin G antibodies, CRP, and fasting glucose from 5,731 participants ≥20 years old receiving oral examinations and providing other health‐related data from the National Health and Nutrition Examination Survey III. The study participants were classified into quartiles of probing depth (PD) and clinical attachment level (CAL). The first quartile was the reference. Logistic regression models with survey procedures were used to explore the roles of inflammation levels from serum CRP and periodontal pathogens on the relations with periodontitis, including PD, CAL, and hyperglycemia, and their joint associations with interaction terms.Results: Stronger associations between PD and diabetes existed in people having elevated CRP and titers for P. gingivalis; odds ratios comparing extreme quartiles of PD were 1.31 and 3.40 in the groups with low and high CRP, respectively, and 1.28 and 2.96 in groups with low and high titers for P. gingivalis, respectively. The joint association patterns were similar for CAL and diabetes.Conclusions: The strengths of association between periodontitis and diabetes were stronger in people having elevated serum CRP and P. gingivalis titers. This may suggest that chronic inflammatory conditions could increase the impact of periodontitis on hyperglycemic status.
Changes in Vitamin C Content and Soluble Solids of Carrot Content (Daucus Carota L.) During Storage / Zmeny v Obsahu Vitamínu C a Rozpustnej Sušiny Mrkvy (Daucus Carota L.) Počas Skladovania
Authors: Valšíková Magdaléna , Šlosár Miroslav , Ryban Rudolf , Shehata Sami , Hegedűsová Alžbeta 
Published: January 2014

Abstract
The average vitamin C content of fresh carrots was 56 mg.kg-1. Amount of vitamin C was reduced by the length of storage and storage environment. On average, the most significant decrease in vitamin C to 24.4 mg.kg-1 under laboratory conditions was reported after 56 days when stored carrots were packed in plastic box. When stored in a refrigerator, the vitamin C content decreased to 24.7 mg.kg-1 after 126 days of storage in a plastic box. During both experimental periods in laboratory conditions, the most vitamin C was preserved while being wrapped plastic wrap. This way of packaging also enabled relatively long-term preservation of freshness in variety called “Komarno”, which was up to 60 days. The second best option in this respect is the packed carrot in microtene bags. The least convenient was to store the carrots open without packaging. In the case of refrigerated storage, the options of packaging in plastic wrap and microtene bags were also the best. The most significant decline in vitamin C was found in the variant without packaging and in the food box. Average soluble solids (refractometry dry matter) content in fresh roots reached 7.6%. During storage under laboratory conditions, the SS values increased to 14.8% after 14 days when the carrot was stored open without packaging. In the refrigerator, the soluble solids content in carrots increased to 12.7% after 28 days of storage without packaging. Increase in soluble solids content was mainly caused by transpiration process. Under laboratory conditions, evaporation and increase of soluble solids were faster compared to the variants stored in the cooler