bluuebunny/crossref_metadata_2025_split huggingface dataset:
Wafer‐Scale Growth and Transfer of High‐Quality MoS2 Array by Interface Design for High‐Stability Flexible Photosensitive Device
Authors: Lü Bingchen , Chen Yang , Ma Xiaobao , Shi Zhiming , Zhang Shanli , Jia Yuping , Li Yahui , Cheng Yuang , Jiang Ke , Li Wenwen , Zhang Wei , Yue Yuanyuan , Li Shaojuan , Sun Xiaojuan , Li Dabing 
Published: July 2024

AbstractTransition metal disulfide compounds (TMDCs) emerges as the promising candidate for new‐generation flexible (opto‐)electronic device fabrication. However, the harsh growth condition of TMDCs results in the necessity of using hard dielectric substrates, and thus the additional transfer process is essential but still challenging. Here, an efficient strategy for preparation and easy separation‐transfer of high‐uniform and quality‐enhanced MoS2 via the precursor pre‐annealing on the designed graphene inserting layer is demonstrated. Based on the novel strategy, it achieves the intact separation and transfer of a 2‐inch MoS2 array onto the flexible resin. It reveals that the graphene inserting layer not only enhances MoS2 quality but also decreases interfacial adhesion for easy separation‐transfer, which achieves a high yield of ≈99.83%. The theoretical calculations show that the chemical bonding formation at the growth interface has been eliminated by graphene. The separable graphene serves as a photocarrier transportation channel, making a largely enhanced responsivity up to 6.86 mA W−1, and the photodetector array also qualifies for imaging featured with high contrast. The flexible device exhibits high bending stability, which preserves almost 100% of initial performance after 5000 cycles. The proposed novel TMDCs growth and separation‐transfer strategy lightens their significance for advances in curved and wearable (opto‐)electronic applications.
Dithiocarbamate‐Based Solution Processing for Cation Disorder Engineering in AgBiS2 Solar Absorber Thin Films
Authors: Ha Neul , Lee GwangHee , Park Jaemin , Lee Joo‐Hong , Jung Jisu , Barma Sunil V. , Kim Jugyoung , Kim Ji Hoon , Kim Jung Kyu , Kwon Seok Joon , Lee Sang Uck , Jeong Sohee , Jo Sae Byeok , Lee Jin‐Wook , Yang Wooseok 
Published: July 2024

AbstractCation disorders refer to the phenomenon where cations are randomly distributed in multi‐cation systems. These disorders have emerged as an effective strategy for tailoring material properties across diverse applications. Notably, engineering cation disorder in AgBiS2 has garnered attention, owing to its remarkable enhancement of light absorption coefficients, which are crucial for efficient solar energy conversion in ultrathin light absorber layers. In this study, a novel dithiocarbamate (DTC)‐based solution processing method designed to control cation disorder is presented in AgBiS2 thin films. Unlike conventional approaches that rely on heat treatment, the strategy is based on molecular coordination dynamics between DTC and metal cations. By adjusting the ratio of DTC to the metal cations, the formation of cation‐disordered AgBiS2 thin films is demonstrated. Notably, the order‐to‐disorder transition is solely dependent on the DTC‐metal coordination and independent of the annealing temperature. These disordered films exhibit a high light absorption coefficient (>5 × 105 cm−1), mirroring the characteristics of thermally‐treated cation‐disordered AgBiS2 nanocrystals reported previously. The disordered AgBiS2 thin‐film photodetector exhibited a higher photocurrent density and responsivity compared to its ordered counterpart. The approach establishes a novel platform for cation disorder engineering, paving the way for advancements in cation‐disordered materials with diverse applications.
Impact of allelochemicals from shade trees bark on the performance of cocoa seedlings
Authors: Danso Jacob , Boadu Isaac Kankam , Sarkodie‐Addo Joseph , Opoku‐Agyeman Michael O. , Padi Francis , Ulzen Jacob , Arthur Alfred 
Published: July 2024

AbstractShade trees are important in cocoa agroforestry systems; however, they release allelochemicals from various parts that affect understory plants. Unfortunately, information on allelochemicals produced by shade tree bark in cocoa plantation remain scarce. This study investigates the effect of allelochemicals from bark of shade trees on cocoa seedlings growth. The experiment was a 4 × 11 factorial study, and the treatments were four different concentrations from each of the 11 tree species. The treatments were laid out in a completely randomized design with four replicates. Data were collected at 30, 60, 90, 120, and 150 days after treatment applications. The tree species alone and bark extract concentrations alone significantly impacted plant height from 90 to 150 days after application. Albizia ferruginea (Guill. & Perr.) Benth, Celtis mildbraedii Engl., and Triplochiton scleroxylon K. Schum produced the highest cocoa seedling heights. All concentrations also influenced stem diameter of cocoa seedlings. Albizia ferruginea enhanced stem diameter significantly among tree species and the control. Tree species and bark extract concentrations interacted to increase fresh root weights and dry plant biomass. Albizia ferruginea consistently increased dry plant biomass, while C. mildbraedii produced the highest enhancement for fresh roots. All concentrations enhanced plant biomass, with the 75 mg mL−1 concentration consistently producing the highest plant fresh and dry weights. Albizia ferruginea and C. mildbraedii can be potential tree species in the cocoa agroforestry when 2‐month‐old cocoa seedlings are to be transplanted on the field. Bark extract of 75 mg mL−1 concentration can be used as a growth stimulant on cocoa seedlings.
Are SCN2A‐related BFNISs also responsible for seizures in adulthood? A case report opens new scenarios
Authors: Brunetti Sara , Muda Alice , Conti Chiara , Gazzina Stefano , Accorsi Patrizia , Giordano Lucio 
Published: July 2024

AbstractLarge cohort studies and variant‐specific electrophysiology have enabled the delineation of different SCN2A‐epilepsy phenotypes, phenotype–genotype correlations, prediction of pharmacosensitivity to sodium channel blockers, and long‐term prognostication for clinicians and families. One of the most common clinical presentations of SCN2A pathological variants is benign familial neonatal‐infantile seizures (BFNIS), which are characterized by seizure onset between the first day of life and 23 months of age and typically resolve, either spontaneously or with the aid of sodium channel blockers, within the first 2 years of life. In 2004, Berkovic et al. reported the case of a young boy affected by SCN2A‐related BFNIS whose mother, who carried the same pathological variant, had also presented with BFNIS in infancy. Our case report focuses on the aforementioned woman who, more than 40 years later, presented two additional seizures, therefore opening the possibility of a role for SCN2A‐related seizures in adulthood.
Developments in the study of Chinese herbal medicine's assessment index and action mechanism for diabetes mellitus
Authors: Liu Xin‐Yue , Zheng Han‐Wen , Wang Feng‐Zhong , Atia Tul‐Wahab , Fan Bei , Wang Qiong 
Published: July 2024

AbstractIn traditional Chinese medicine (TCM), based on various pathogenic symptoms and the ‘golden chamber’ medical text,Huangdi Neijing, diabetes mellitus falls under the category ‘collateral disease’. TCM, with its wealth of experience, has been treating diabetes for over two millennia. Different antidiabetic Chinese herbal medicines reduce blood sugar, with their effective ingredients exerting unique advantages. As well as a glucose lowering effect, TCM also regulates bodily functions to prevent diabetes associated complications, with reduced side effects compared to western synthetic drugs. Chinese herbal medicine is usually composed of polysaccharides, saponins, alkaloids, flavonoids, and terpenoids. These active ingredients reduce blood sugar via various mechanism of actions that include boosting endogenous insulin secretion, enhancing insulin sensitivity and adjusting key enzyme activity and scavenging free radicals. These actions regulate glycolipid metabolism in the body, eventually achieving the goal of normalizing blood glucose. Using different animal models, a number of molecular markers are available for the detection of diabetes induction and the molecular pathology of the disease is becoming clearer. Nonetheless, there is a dearth of scientific data about the pharmacology, dose‐effect relationship, and structure–activity relationship of TCM and its constituents. Further research into the efficacy, toxicity and mode of action of TCM, using different metabolic and molecular markers, is key to developing novel TCM antidiabetic formulations.
Aluminiumalkylinduzierte Isomerisierung von Gruppe IV meso Metallocen Komplexen
Authors: Lenz Tim M. , Chiorescu Ion , Napoli Fabrizio E. , Liu Jin Y. , Rieger Bernhard 
Published: July 2024

AbstractBei der Synthese von Gruppe IV Metallocen‐Präkatalysatoren für die Polymerisation von Propylen werden im Allgemeinen zwei verschiedene Isomere gebildet: Das racemische Isomer, das isotaktisches Polypropylen (iPP) produziert und das meso‐Isomer, das ataktisches Polypropylen (aPP) produziert. Aufgrund seiner vergleichbar schlechten physikalischen Eigenschaften ist die Anwendung von aPP sehr begrenzt. Um Mischungen beider Polymere zu vermeiden, was die mechanischen und thermischen Eigenschaften von iPP zu verschlechtern würde, müssen die meso Metallocenkomplexe mühsam von den racemischen Komplexen getrennt werden, was die Metallocen‐basierte Polymerisation von Propylen industriell weit weniger attraktiv macht als das Ziegler/Natta‐Verfahren. Um dieses Problem zu umgehen, haben wir ein Isomerisierungsprotokoll zur Umwandlung von meso Metallocenkomplexen in ihre racemischen Analoga entwickelt. Dieses Protokoll steigerte die Ausbeute an iPP um 400 %, wobei die hervorragenden physikalischen Eigenschaften des Polymers beibehalten wurden; es war sowohl auf Hafnocen‐, als auch auf Zirkonocenkomplexe, sowie auf verschiedene Methoden zur Aktivierung des Präkatalysators anwendbar. Durch gezielte Variation der Liganden wurden Methoxygruppen an den Indenylsubstituenten als die für eine Isomerisierung verantwortlichen Strukturmotive gefunden ‐ dieser experimentelle Nachweis wurde durch Dichtefunktionaltheorieberechnungen bestätigt. Flüssig‐Injektion‐Feld‐Desorption‐Ionisierung‐Massenspektrometrie, sowie 1H‐ und 29Si‐Kernresonanzstudien ermöglichten den Vorschlag eines Isomerisierungsmechanismus.
Electrosynthesis of Transition Metal Coordinated Polymers for Active and Stable Oxygen Evolution
Authors: Wang Xiao , Liu Fangming , Qin Hongye , Li Jinhan , Chen Xijie , Liu Kuiming , Zhao Tete , Yang Wanling , Yu Meng , Fan Guilan , Cheng Fangyi 
Published: July 2024

AbstractTransition metal coordination polymers (TM‐CP) are promising inexpensive and flexible electrocatalysts for oxygen evolution reaction in water electrolysis, while their facile synthesis and controllable regulation remain challenging. Here we report an anodic oxidation‐electrodeposition strategy for the growth of TM‐CP (TM=Fe, Co, Ni, Cr, Mn; CP=polyaniline, polypyrrole) films on a variety of metal substrates that act as both catalyst supports and metal ion sources. An exemplified bimetallic NiFe‐polypyrrole (NiFe‐PPy) features superior mechanical stability in friction and exhibits high activity with long‐term durability in alkaline seawater (over 2000 h) and anion exchange membrane electrolyzer devices at current density of 500 mA cm−2. Spectroscopic and microscopic analysis unravels the configurations with atomically distributed metal sites induced by d‐π conjugation, which transforms into a mosaic structure with NiFe (oxy)hydroxides embedded in PPy matrix during oxygen evolution. The superior catalytic performance is ascribed to the anchoring effect of PPy that inhibits metal dissolution, the strong substrate‐to‐catalyst interaction that ensures good adhesion, and the Fe/Ni−N coordination that modulates the electronic structures to facilitate the deprotonation of *OOH intermediate. This work provides a general strategy and mechanistic insight into building robust inorganic/polymer composite electrodes for oxygen electrocatalysis.
High‐Performance Piezoelectric Two‐Dimensional Covalent Organic Frameworks
Authors: Gu Qianfeng , Lu Xiangqian , Chen Cailing , Wang Xiang , Kang Fangyuan , Li Yang Yang , Xu Qingfeng , Lu Jianmei , Han Yu , Qin Wei , Zhang Qichun 
Published: July 2024

AbstractOrganic piezoelectric nanogenerators (PENGs) are attractive in harvesting mechanical energy for various self‐powering systems. However, their practical applications are severely restricted by their low output open circuit voltage. To address this issue, herein, we prepared two two‐dimensional (2D) covalent organic frameworks (COFs, CityU‐13 and CityU‐14), functionalized with fluorinated alkyl chains for PENGs. The piezoelectricity of both COFs was evidenced by switchable polarization, characteristic butterfly amplitude loops, phase hysteresis loops, conspicuous surface potentials and high piezoelectric coefficient value (d33). The PENGs fabricated with COFs displayed highest output open circuit voltages (60 V for CityU‐13 and 50 V for CityU‐14) and delivered satisfactory short circuit current with an excellent stability of over 600 seconds. The superior open circuit voltages of CityU‐13 and CityU‐14 rank in top 1 and 2 among all reported organic materials‐based PENGs.
Plasma exchange and intravenous immunoglobulin for the peri‐operative management of type 2 heparin‐induced thrombocytopaenia in a patient requiring urgent surgery for critical limb ischaemia
Authors: Perera Y. , Taylor R. , Bera K. D. , Holman L. , Curry N. , Shah A. 
Published: July 2024

SummaryWe report the case of a 61‐year‐old female who developed heparin‐induced thrombocytopaenia following treatment of a submassive pulmonary embolism, and who then required an above knee amputation for critical limb ischaemia. Heparin‐induced thrombocytopaenia is a rare, immune‐mediated complication associated with an in‐hospital mortality rate of 10%. It is more common in surgical patients, with patients undergoing orthopaedic surgery more likely to develop it than patients undergoing cardiac surgery, but heparin‐dependent immunoglobulin G antibodies are more likely to be formed in the latter. Peri‐operative management remains a challenge. Ideally, it is preferable to wait for the platelet count to improve; but in certain cases, surgery cannot be delayed. Heparin‐induced thrombocytopaenia is usually managed with direct thrombin inhibitors, such as argatroban and bivalirudin. Newer therapeutic modalities, such as plasmapheresis and intravenous immunoglobulin, as used in this case, can rapidly remove antibodies, but the certainty of evidence is low. Our case adds to the literature regarding the use of these modalities and highlights the multidisciplinary team approach required to manage such complex cases.
Features of the modern development of metal‐insulator‐metal waveguide based plasmonic sensors
Authors: Butt Muhammad Ali 
Published: July 2024

AbstractPlasmonic sensors based on metal‐insulator‐metal (MIM) waveguides are renowned for their miniaturization and high sensitivity in various sensing applications. A broad spectrum of researchers is numerically investigating the characteristics of MIM waveguide‐based plasmonic sensors with diverse cavity shapes. However, practical demonstrations of these sensors have not yet been realized, primarily due to the overlooked aspect of the light coupling mechanism into these waveguides. In this context, two distinct methods for coupling light into and out of plasmonic chips based on MIM waveguides are presented.
Mapping and Analysis of Protein and Gene Profile Identification of the Important Role of Transforming Growth Factor Beta in Synovial Invasion in Patients With Pigmented Villonodular Synovitis
Authors: Li Tao , Xiong Yan , Li Jian , Tang Xin , Zhong Yutong , Tang Zhigang , Zhang Qiuping , Luo Yubin 
Published: July 2024

ObjectivePigmented villonodular synovitis (PVNS) is a rare benign proliferative disease affecting the soft‐tissue lining the synovial joints and tendons. Its etiology is poorly understood, largely limiting the availability of current therapeutic options. Here, we mapped the synovial gene and protein profiles of patients with PVNS, revealed a link between synovial inflammation and invasion, and elucidated the potential molecular mechanism involved.MethodsThe expression of synovial genes from 6 control individuals, 7 patients with osteoarthritis (OA), and 19 patients with PVNS was analyzed via RNA sequencing. Protein profiles from 5 control individuals, 10 patients with OA, and 32 patients with PVNS were analyzed using label‐free proteomics. Microarray and reverse transcription–polymerase chain reaction analyses and immunohistochemical staining were used to evaluate inflammatory cytokine and target gene expression levels in synovial tissue, epithelial cells, and synovial fibroblasts (FLSs) derived from tissue of patients with PVNS. Various signaling pathway inhibitors, small interfering RNAs, and Western blots were used for molecular mechanism studies. Transwell migration and invasion assays were subsequently performed.ResultsIn total, 522 differentially expressed proteins were identified in the tissues of patients with PVNS. By integrating RNA sequencing and microarray analyses, significant changes in the expression of epithelial–mesenchymal transition (EMT)‐related genes, including transforming growth factor TGF‐b induced, neural cadherin, epithelial cadherin, SNAIL, and TWIST, were confirmed in the tissue of patients with PVNS compared to the control tissue. In vitro, TGFβ induced EMT and increased epithelial cell migration and invasion. Moreover, TGFβ not only promoted interactions between epithelial cells and FLSs but also directly increased the migration and invasion abilities of FLSs by activating the classical Smad2/3 and nonclassical JNK/AKT signaling pathways.ConclusionThis study provides overall protein and gene profiles of PVNS and identifies the crucial role of TGFβ in synovial invasion pathology. Exploring the related molecular mechanism may also reveal a new strategy or target for PVNS therapy.
Dynamic event‐triggered control of 2‐D continuous systems in Roesser model
Authors: Hu Hongsheng , Meng Yunhe , Huang Shipei 
Published: July 2024

AbstractIn this paper, a dynamic event‐triggered control problem is discussed for 2‐D continuous systems by the Roesser model. In order to reduce communication frequency and avoid dependence on global information, a dynamic event‐triggered mechanism is constructed, which is more flexible than some existing event‐triggered schemes with fixed event‐triggered thresholds. Utilizing the dynamic event‐triggered mechanism, a state feedback controller is designed. By constructing a 2‐D Lyapunov function, sufficient conditions expressed in terms of linear matrix inequalities (LMIs) are firstly established such that the 2‐D system is asymptotically stable with a disturbance attenuation performance. It is also proved that the Zeno phenomenon is excluded. Finally, two examples are provided to illustrate the effectiveness of the proposed method.
Longitudinal changes in executive function in autism spectrum disorder: A systematic review and meta‐analyses
Authors: Yeung Michael K. , Bai Jieru , Mak Kwai‐Lai 
Published: July 2024

AbstractIndividuals with an autism spectrum disorder (ASD) diagnosis show impairment in executive function (EF). However, findings are mixed regarding differences in the age effect on EF between autistic individuals and persons with typical development (TD). Questions remain regarding whether the age‐related trajectories of EF in ASD are the same as or different from those in TD. To bridge this knowledge gap, we conducted a systematic review and meta‐analyses of longitudinal studies that compared age‐related changes in EF between ASD and TD groups (preregistration: osf.io/j5764). A literature search was conducted using PubMed, PsycINFO, and Web of Science on January 29, 2024. After screening by two independent reviewers, 14 longitudinal studies were included. Random‐effects meta‐analyses of studies involving a maximum total of 518 autistic and 3558 TD children and adolescents (mean baseline ages: 5.7–12.0 years) showed that ASD had significantly poorer EF than TD at both baseline and follow‐up. However, there was no significant group difference in the age‐related change in EF across domains, including working memory, inhibition, shifting, and planning. Robust Bayesian meta‐analyses also provided substantial evidence in favor of the null hypothesis that ASD and TD groups showed similar changes over time for most EF processes. Limitations of the literature included the limited number of longitudinal studies and a narrow range of developmental stages and EF constructs analyzed across studies. Altogether, these findings suggest that autistic children and adolescents generally can improve in EF over time similarly to their neurotypical peers. This has important implications for parents and educators, encouraging appropriate EF training and intervention for autistic children and adolescents at an early stage.
Green micellar factorial design optimized first derivative synchronous spectrofluorimetric method for tripelennamine and diphenhydramine determination in pharmaceutical gel
Authors: Amer Mona M. , El‐Khateeb Basma Z. 
Published: July 2024

AbstractA green micellar synchronous spectrofluorimetric method was developed and validated for simultaneous determination of tripelennamine hydrochloride and diphenhydramine in bulk and combined pharmaceutical formulation. Synchronous fluorescence of tripelennamine hydrochloride and diphenhydramine was determined using Δλ = 60 nm. The first derivative of synchronous fluorescence was computed to resolve overlap in the synchronous fluorescence spectra. Tripelennamine hydrochloride was quantified at 375 nm, whereas diphenhydramine was quantified at 293 nm; each is the zero‐crossing point of the other. As diphenhydramine exhibited weak native fluorescence, micelle enhancement upon incorporation of sodium dodecyl sulfate was considered. Two‐level full factorial design was carried out to optimize experimental parameters. Optimum conditions involved using SDS (2% w/v) along with Teorell and Stenhagen buffer (pH 9). The method was found to be linear over the range 0.2–4.5 and 0.2–5 μg/mL for tripelennamine and diphenhydramine, respectively, with limits of detection 0.211 and 0.159 μg/mL. The method was successfully applied for simultaneous determination of tripelennamine hydrochloride and diphenhydramine in laboratory‐prepared gel containing all possible excipients with mean percent recoveries ±SD 100.59 ± 0.79 and 98.99 ± 0.98 for tripelennamine hydrochloride and diphenhydramine, respectively. The proposed method was proved to be eco‐friendly using different greenness assessment tools.