bluuebunny/crossref_metadata_2025_split huggingface dataset:
Insights into the Biomedical and Pharmaceutical Potential of Deleserriaceae: A Comprehensive Review
Authors: Malhotra Rohit , Cojandaraj Louis 
Published: June 2024

Abstract:
The family Delesseriaceae possesses enormous bioactive medicinal and pharmacological
constituents that have calculable positive effects on various diseases in humans. The Delesseriaceae
family contains approximately 25 different marine species that are found throughout coastal areas.
This review aims to integrate global scientific literature, including seaweed studies in Mandapam, to
provide a comprehensive understanding of Deleserriaceae species, encompassing taxonomy, ecology,
and potential applications. Nitophyllum species contain bioactive components, especially polysaccharides
and proteins. Deleseriaceae, a seaweed recognized for its nutritional richness, presents a
potential resource for various therapeutic applications. However, it's important to note that the specific
activities mentioned, such as insulin sensitization, lipid peroxidation inhibition, antimicrobial
effects, and antioxidant properties, might not be well-documented or established in Deleserriaceae
species such as Nitophyllum marginale, Nitophyllum punctatum, Nitophyllum hommersandii venvorstia
spectabilis, Martensia indica, Taenioma perpusilium, and Martensia fragilis. Further research
is required to ascertain the exact bioactive compounds and potential health benefits associated with
this seaweed species.
Comprehensive Review on Alzheimer’s Disease: Natural Therapeutics, Gaps and Challenges
Authors: Mishra Prem Shankar , Mishra Rakhi , Kumar Anuj 
Published: June 2024

Abstract:
More than 20 million people worldwide have Alzheimer's disease (AD), making it the
most prevalent disease. Patients with AD may live for at least a decade after diagnosis, making it
the most common cause of disability in the elderly. Each year, 1% to 4% of the population is affected
by AD, with prevalence peaking between ages 65 and 70 and declining to 6% among those
over 85. Researchers have accumulated evidence on medicinal herbs that may reverse the pathogenesis
of Alzheimer's disease. Alzheimer's disease (AD) is associated with severe memory loss,
which can negatively impact social and professional life. The first neurotransmitter linked to Alzheimer's
was acetylcholine (ACh). There is no known cure, and the available treatments are ineffective.
Multiple studies indicate that Ayurvedic restorative herbs and their constituents may be effective
in treating Alzheimer's disease. This technique emphasizes the fact that delaying or preventing
Alzheimer's disease with the help of natural bio-actives could reduce the number of cases over
the next half-century. To provide detailed information, the pathology and pathophysiology of Alzheimer's
Disease are discussed in the text of this review, along with an overview of the neurotransmitters
involved in the progression of the disease. The importance of different natural bioactives
for the treatment of Alzheimer's disease is also outlined in the paper. The information contained
in this paper can serve as a template for future research expressing the more beneficial role
of other bioactive in acting as an adjuvant in the prevention and treatment of this disease, facing
certain challenges and gaps with conventional drugs used to treat Alzheimer's disease.
Enhancing Medical Image Security through a Novel Framework: Crypto-aware Elliptic Curve Diffie-hellman with Key Derivation Function
Authors: Senthilkumar M. , Suthendran K. , Ravi Vinayakumar 
Published: June 2024

Aim
To develop and apply advanced methods to enhance medical image security, ensuring patient data integrity, confidentiality, and authenticity throughout the stages of image collection, transmission, and storage.

Background
Retaining patient privacy and data accuracy in the context of accessible healthcare require the secure broadcast and storage space of medical imaging. Because of the increasing dependence on digital medical imaging technology, it is essential to protect these private images from illegal access and possible cyber attacks.

Objective
Work addresses the drawbacks of conventional encryption techniques in the healthcare sector and offers a novel Crypto-Aware Elliptic Curve Diffie Hellman with Key Derivation Function (CAECDH-KDF) encryption technique to improve the security of medical images.

Methods
The suggested encryption architecture combine domain-specific methods designed for medical imaging data with sophisticated cryptographic algorithms. The framework, in difference to conservative encryption methods, employs an effective tactic that strikes a compromise between processing speed and security. To achieve this, better encryption methods for medical image characteristics are incorporated.

Results
Comparisons are made between the suggested method's security, computation time (0.003001), encryption time (0.001998s), decryption time (0.001001s), entropy (7.997633), and throughput (4.0887) of conventionally encrypted approaches.

Conclusion
A large amount of test images have been utilized to evaluate the effectiveness of the suggested technique. According to numerous tests, the suggested strategy outperforms conventional methods.
Plasma Protein Adsorption on Melphalan Prodrug Bearing Liposomes - Bare, Stealth, and Targeted
Authors: Kobanenko Maria , Samofalov Pavel , Kapitonova Irina , Alekseeva Anna , Kapkaeva Marina , Scheglovitova Olga , Tuzikov Alexander , Tretiakova Daria , Vodovozova Elena 
Published: June 2024

Background:
Plasma protein binding is inevitable for nanomaterials injected into blood circulation. For liposomes, this process is affected by the lipid composition of the bilayer. Membrane constituents and their ratio define liposome characteristics, namely, surface charge and hydrophobicity, which drive protein adsorption. Roughly 30 years ago, the correlation between the amount of bound proteins and the resulting circulation time of liposomes was established by S. Semple, A. Chonn, and P. Cullis. Here, we have estimated ex vivo plasma protein binding, primarily to determine the impact of melphalan prodrug inclusion into bilayer on bare, PEGylated (stealth), and Sialyl Lewis X (SiaLeX)-decorated liposomes.

Experimental:
Liposomes were allowed to bind plasma proteins for 15 minutes, then liposome-protein complexes were isolated, and protein and lipid quantities were assessed in the complexes. In addition, the uptake by activated HUVEC cells was evaluated for SiaLeX-decorated liposomes.

Results::
Melphalan moieties on the bilayer surface enrich protein adsorption compared to pure phosphatidylcholine sample. Although PEG-lipid had facilitated a significant decrease in protein adsorption in the control sample, when prodrug was added to the composition, the degree of pro-tein binding was restored to the level of melphalan liposomes without a stealth barrier. A similar effect was observed for SiaLeX-decorated liposomes.

Conclusion:
None of the compositions reported here should suffer from quick elimination from circulation, according to the cut-off values introduced by Cullis and colleagues. Nevertheless, the amount of bound proteins is sufficient to affect biodistribution, namely, to impair receptor recog-nition of SiaLeX and reduce liposome uptake by endothelial cells.
A familia sometida a un exercicio de enxeñería conceptual
Authors: Permuy Aixa , Latorre Ruíz Enrique 
Published: June 2024

Contra-relatar a idea de familia, ou incluso falar de abolila, semella un imperativo a recuperar fronte a todas esas violencias que acompañan as loitas polas liberdades das disidencias sexuais e de xénero. Ademais de polas demandas, pasadas e presentes, de outras formas de estar no mundo e relacionarse, á marxe dos itinerarios vitais cisheterosexuais monógamos; aínda que nada haxa máis importante que a familia.
Sábese que hai algo que asusta cando se fala de abolición, tal como reflexiona Lewis (2023); porque isto obriga a un desafío senti-mental bastante aterrador: “pero, se eu quero á miña familia!”.
O presente traballo pretende, a través dun exercicio de enxeñería conceptual, analizar a familia, recordando que os significantes non son esenciais, senón simples obxectos de acción, ferramentas que producimos para afrontar a realidade e, por tanto, elementos susceptibles de avaliación e, segundo o caso, de reparación.
Nun momento no que o concepto de familia parece non funcionar, propoñemos unha reflexión favorable á postura abolicionista, sobre os seus límites e naufraxios, acompañada dunha proposta de intervención socioeducativa, enmarcada nunha pedagoxía queer dos afectos, resultado de repensar ese lugar ao que pertencer, onde sentirse a salvo e fabricar mundo.
Legal Protection for Children in Cases of Domestic Violence in the Indonesian Households
Authors: Alifiyah Rifdah , Anshori Isa 
Published: June 2024

This study aims to investigate and evaluate the many legal protections available to children who experience domestic abuse. Additionally, it seeks to provide a comprehensive framework for enhancing legal protection measures specifically designed for child victims of domestic violence. This study employs a normative approach to analyze legal issues by examining legislation. The material examined pertains to legal statutes and laws concerning instances of familial child abuse. This study establishes that child domestic violence can manifest in various forms, including physical, sexual, emotional, neglect, and economic abuse. The act of violence infringes upon the rights of children and adversely affects their overall welfare, leading to diminished cognitive abilities, impaired emotional regulation, challenges in social interaction, psychological developmental disorders, difficulties in establishing relationships and trust, increased susceptibility to depression and anxiety disorders, and various mental health issues. The legal safeguarding of children in Indonesia is governed by Law No. 23/2002 on Child Protection, which was subsequently revised by Law No. 35/2014. This legislation serves as the legal foundation for the protection of children, including all endeavors aimed at ensuring their safety, well being, and the fulfillment of their rights to thrive, mature, progress, and engage fully.
The Tradition of Tepuk Tepung Tawar in Malay Weddings from the Perspective of Islamic Law: A Case Study at Tanjungpinang, Riau Islands
Authors: Ardiansyah Ogie , Masrokhin Masrokhin 
Published: June 2024

Tepuk Tepung Tawar is a ritual in the Malay wedding ceremony, especially in Kampung Melayu of Kota Tanjungpinang Subdistrict. This tradition is also carried out for children who have completed their Qur’an recitation, with prayers for their safety, well-being, and protection from hardship in life. This present study used a sociological method, in which data were analyzed by using the theory of ‘urf (social custom) in Islamic law. Data were collected by means of interview and document study. This study revealed that historically, the tepung tawarceremony for newlyweds would be carried out alternately for each, considering that they have not yet had mahar batih (not yet consummated), while the tepung tawar ceremony for both would be carried out for longtime married couples. The Malay people are very strong in observing their customs and traditions; even giving rise to the Malay proverb “biar mati anak dari pada mati adat”, better for a child to die than for a custom to die. This proverb illustrates how deeply the Malay people are in upholding the customs and traditions of their ancestors. Theoretically, there is also harmony between Islamic law and ‘urf or social custom in Malay weddings.
Settlement of the Fulfillment of Wife and Child Livelihood by the Islamic Religious Council Southern Patani Region of Thailand
Authors: Darmawijaya Edi , Ma'ming Miss Maslinee 
Published: June 2024

Livelihood is all the needs and necessities that occur according to circumstances and places, such as food, clothing, shelter, assistance, and all his needs according to tradition because the law of subsistence is an obligation of a husband towards his wife and family. The Islamic Religious Council (MAIP) of Patani Region has a special working position namely Qadhi which handles matters related to family matters, in the Islamic Religious Council of Southern Patani Thailand does not have a Law or Compilation of Islamic Law (KHI) like Indonesia, but the responsible party will handle issues related to the family rights of Muslims by referring to the fiqh of Imam Shafi'i. In the case of non-fulfillment of the support of wives and children according to the religious assembly, for the Islamic religious assembly, there is no written fatwa, only a letter of agreement that can be an important asset in resolving the problem. This research uses qualitative methods, taking the background of informants, data collection is carried out using observation, interviews, and documentation. The results of this study concluded that after the marriage bond held a taklik letter (agreement) between husband and wife because it held a taklik made by the Islamic Religious Council (MAIP) so that the husband did not commit violence against his wife unfairly and followed shari'i, husbands who did not follow the taklik letter (Agreement) then the wife could complain to the Village Imam or the Islamic Religious Council (MAIP). The wife must bring two witnesses or concrete evidence, the Islamic Religious Council (MAIP) will give advice related to Islamic teachings that follow shari'a law so that peace arises between husband and wife then husband and wife may be added a taklik letter that has been determined by the Islamic Religious Council (MAIP) for the problem of not fulfilling income with the agreement between husband and wife, and the husband does not provide for himself, hurts and does not occupy the position for more than four months the wife may be fasahk
physiochemical and Sensory Properties of Pumpkin and Strawberry Jams Fortified with Chia Seed ( Salvia Hispanica L)
Authors: Saleem Mahmood F. , Ahmed Salar A. , Galali Yaseen , Sebo Nawal H. , Yildrim Ali , Najmdaddin Begard S. 
Published: June 2024

Supplementation of jams with functional ingredients is one of the methods to develop healthier jams. The aim of this research was therefore to develop functional jams supplemented with chia seed (CS). Five formulations of two types of jams were selected (pumpkin (PJ) and strawberry jams (SJ) ) with different levels ( 0, 1.5, 3, 4.5 and 6% ) of CS was added. The jams were assessed chemically, sensorial and nutritionally a using ICP-OES. The results showed that the introduction of CS into PJ significantly increased protein, ash, cellulose content from 0.35%, 0.55 and 46.43 of control to 0.77%, 1.01 and 54.18 of sample containing 6% CS respectively. However pH, acidity and moisture decreased. Similarly protein, ash , cellulose of SJ jam increased from 0.44%, 0.58 and 14.55 of control sample to 0.93%, 0.93 and 16.75 of sample containing 6% CS respectively. Unlike PJ pH, and moisture increased with addition of CS. Antioxidant and total phenol content were not noticeably changed. The sensory data discovered that the addition of CS adversely affected all sensory attributes parallel with CS addition both jams, but appearance color and taste were more influenced particularly in PJ. The addition of CS in PJ increased the content of calcium, iron and zinc from <0.05 mg/kg (control) to 1121, 6.74 and 2.36 respectively. . In conclusion, the data of this study showed the PJ and SJ can be produced by the addition of as high as 6% CS with improved nutritional value and acceptable sensorial properties.
Miracles from the Perspective of the Catholic Church
Authors: Chandrankunnel M. , Lyutaeva M. S. 
Published: June 2024

The article delves into the concept of miracles from the perspective of the Catholic Church, tracing the evolution of human consciousness from fear to awe to curiosity, leading to the phenomena of mythologization, religious experiences, philosophical explanations, and rational understanding of everyday events through science and technology. The relevance of the study is due to the great influence and role of the Catholic Church in the modern world. Miracles as one of the key phenomena related to Catholic values are examined. By means of categorial and discourse analyses, along with the case study method, the work highlights the theological interpretation of miracles, distinguishing between official Christian doctrines and vernacular religious practices. It explores the process of institutionalization of religion and the significance of miracles within the context of Catholicism, emphasizing their role as divine revelations and signs of the supernatural. The article discusses the theological views on miracles of such thinkers as Augustine of Hippo and St. Thomas Aquinas, underscoring how miracles attest to faith and the resurrection. Contemporary examples of miracles recognized by the Catholic Church, such as those at Lourdes and involving figures like St. Padre Pio and Carlo Acutis are outlined. The process of canonization and the phenomenon of stigmata are described. The discussion extends to the philosophical debates on miracles, contrasting rationalistic criticisms from figures like David Hume and Baruch Spinoza with the religious significance attributed to miraculous events. The article also critiques the positivist perspective that subjugates religion to reason and science, emphasizing the enduring nature of miracles in religious discourse despite scientific advancements. In conclusion, the study advocates for a reconnection with the miraculous, religious, and metaphysical realms, positing that embracing mystery and awe can imbue life with meaning, wonder, and purpose, countering the secularization thesis that diminishes the role of miracles and spirituality in the modern world.
Arabic Greeting Etiquette: A Linguocultural Aspect
Authors: Gabdreeva N. V. , A. S. E. Abu Ghriekanah 
Published: June 2024

The article examines speech communication with the example of the various forms of greetings in a number of dialects of the modern Arabic language. The relevance of the study is caused by the intensified contacts between Russia and the Arab world. The theoretical significance is caused by the need to specify the relation between the peculiarities of Arabic as of today and the social, religious and everyday culture of the region. The study aims to identify the most popular forms of greetings in the Arabic language and its five dialects (Levantine, Egyptian, Moroccan, Iraqi and the dialect of the Arab Gulf) widely used across the Middle East and Northen Africa. The following tasks were set: 1) to verify the hypothesis that Arab countries share universal forms of greeting; 2) to outline the specific features of local greetings in the Middle East; 3) to analyze the greeting formulas with regard to the religion, gender, age and social status of speakers; 4) to investigate and hypothesize the origins of linguistic transformations. The materials for the study were collected by the author in the course of involved observation and included field notes from Jordan and interviews with Arab students of the Kazan Federal University. The materials were processed with the help of content-analysis and expert assessment. The study has showed that in the Arab language there exist universal forms of greetings, with local specificities understandable for all those living in the region. The analysis proved that apart from religion, linguocultural factors are at play leading to original multiple-words formulas reducing to one or two words with the same meaning. The reductionist trend is also observed in the phonetical structure of the words, especially among the youth. Providing commentary to the usage of greeting in Arabic, the study is of practical relevance to a wide range of readers because it clarifies the cultural code and helps avoid misunderstanding.
Study of Diversity and Genetic Structure of Cagaita, Cajuzinho-do-Cerrado and Pequi Populations for Conservation and Sustainable Management Purposes
Authors: Silva Pedro Vitor de Souza , Oliveira Leandro Silva , Nunes Rodrigo Magalhães , Sales Nilza de Lima Pereira , Fonseca Rúbia Santos , Sanglard Demerson Arruda 
Published: June 2024

Objective: The aim of this study is to investigate the genetic diversity and population structure of cagaita, cajuzinho-do-cerrado, and pequi populations, with the purpose of providing scientific foundations for the conservation and sustainable management of these plant species.

Theoretical Framework: Investigations into the genetic diversity of species such as cagaita, cajuzinho-do-cerrado, and pequi are fundamental for elucidating their population structures and genetic variability. These studies employ population genetics models and gene flow analyses, forming a robust foundation for determining the conservation and sustainable management needs of these species, which are vital aspects for the preservation of the Cerrado's biodiversity.

Method: Leaf samples were collected from adult individuals of the three species, maintaining a minimum distance of 200 meters between trees, in three locations with different levels of anthropization in the Cerrado. DNA extraction followed the procedures outlined by Doyle and Doyle (1990), with some adaptations. ISSR oligonucleotides from the UBC Collection were used for the PCR reactions, and the products were analyzed by agarose gel electrophoresis. The generated data were processed using binary matrices and the UPGMA method for genetic similarity analysis.

Results and Discussion: The adapted DNA extraction protocol was effective for cagaita and pequi but inefficient for cajuzinho-do-cerrado due to its leathery leaves, suggesting the use of other tissues like floral buds. Dendrograms showed significant genetic diversity among cagaita accessions and similar diversity in pequi. Clustering by genetic similarity indicated small isolated populations, signaling a risk of genetic erosion if forest fragmentation continues, which could affect genotype distribution and compromise species survival.