bluuebunny/crossref_metadata_2025_split huggingface dataset:
L’incertitude et le rêve dans le recueil Lelio de Josef Čapek [Doubts and Dream in Josef Čapek’s Prose Collection Lelio]
Authors: Stolz-Hladká Zuzana 
Published: February 2015

Doubts and Dream in Josef Čapek’s
Prose Collection Lelio
The goal of this article is to demonstrate that dream is not only a central theme in Josef Čapek’s prose, which is varied and developped by the author in Lelio, his prose collection from 1917, but is also a technique of modern art that the artist investigates. The main focus of the dream topic and the dream technique lies on the narratives Lelio (1914) and Rukopis, nalezený na ulici (1915). Searching for modern artistic approaches in painting and poetry Josef Čapek chooses techniques which enlight both, visionary and irreal aspects of the depicted objects. They radically differ from classical procedures in art. In Lelio, a text illustrating dream as an intoxicational state similar to death in Berlioz’ early version already, the alienated and unreliable perspective chosen by Čapek leads to uncertanity concerning all categories of the depicted individuals, objects and situations. The transgression of given borders of identity, materiality and mediality is creating an alternative duplex world. In Rukopis, nalezený na ulici Čapek developpes the theme of dream in a diffent way. He puts it as a shadow which depends on a source and compares it to the characters in a manuscript. Then he follows the literary tradition of Antiquity and its conception of „ eidola“, pictures composing a vision. In this tradition dream is understood as a picture which reflects its prefiguration. In Čapek’s text dream is a vision which enables to anticipate the future existence. The dream as a creative technique of modern art does not stand here for an illusion. It allows the understanding of the object’s true identity and leads to a truthful view of man and his world.
Le rêve comme ouverture et multiplicité d’existence : la recherche d’une « autre » réalité dans les textes de Věra Linhartová [Dream as an Opening and a Proof of the Multiplicity of Life : The Pursuit of ‘Another’ Reality in the Work of Věra Linhartová]
Authors: Košnarová Veronika 
Published: February 2015

Sen jako otevření a mnohost existence : hledání „ druhé“ reality v texteh Věry Linhartové

Studie se zaměřuje na problematiku snu v tvorbě Věry Linhartové, jež sama věnovala tomuto tématu značnou pozornost ve svých odborných studiích o autorech jako jsou Richard Weiner, Jindřich Štyrský či
Jindřich Heisler. Na její vlastní beletristické psaní mělo vliv především pojetí snu Gérarda de Nervala, Richarda Weinera a autorů skupiny Le Grand Jeu. Podněty z těchto koncepcí Linhartová však po svém rozvinula : motiv snu v jejích textech ze šedesátých let slouží především k originálnímu „ osvícení“ vztahu mezi realitou a fikcí z pohledu geneze i recepce literárního díla. Její pozdější francouzsky psané básně v próze, soustředěné do souboru Mes oubliettes, pak lze charakterizovat jako písemné záznamy básnického (bdělého) snění a rozjímání.
Les avatars apocryphes du personnage de Judas dans la prose tchèque contemporaine [The Apocryphal Metamorphoses of Judas in Contemporary Czech Prose]
Authors: Hrtánek Petr 
Published: February 2015

The Apocryphal Metamorphoses of Judas in Contemporary Czech Prose
The essay deals with the inter-textual metamorphoses of the characters of Judas in contemporary Czech apocryphal re-workings of evangel pre-texts. The novels Judas ´ Cross (Kříž Jidášův, 1988) by L. Tomek, The Lord of the Tower (Pán věže, 1992) by E. Kantůrková and The Lamb (Beránek, 2000) by L. Procházková and stories Judas (Jidáš, 2002) by J. Vácha and The Evangelist (Evangelista, 2004) by I. Dousková are the main subjects of presented analyses and comparisons. The essay examines the typical changes in characterization of Judas, therein after pays attention to modifications of roles that the character of Judas plays in the apocryphal versions of the gospel story. Simultaneously the essay does not omit various exchanges and disguising of identity of this character. While the character of Judas is the definite type in the New Testament, the produced apocryphal metamorphoses tend to the semantic inception of this character : the character of Judas is involved in unexpected analogies and parallels, becomes the part of allegorical depiction of reality or becomes the bearer of philosophizing sentences.
К вопросу о возникновении имен числительных как самостоятельной части речи в древнерусском языке (на материале Синайского патерика) [On the Genesis of Numerals as an Independent Part of Speech in Old Russian Language (On the Material of “Sinai Patericon”)]
Authors: Pozsgai István 
Published: February 2015

À propos de l’émergence des numéraux comme partie du discours indépendante en vieux russe (À partir du Paterikon du Sinaï)
Ce travail a pour but d’examiner le système de l’accord des numéraux dans le Paterikon du Sinaï, manuscrit copié d’un manuscrit vieux-slave dans l’aire vieux-russe des XIe-XIIe siècles. L’auteur étudie principalement les phénomènes qui peuvent nous renseigner sur les conditions de l’émergence d’une nouvelle partie du discours indépendante, dans le cas présent, celle des numéraux. L’auteur présente les types d’accord des numéraux et s’intéresse aux phénomènes qui peuvent être reliés à l’unification des différents types d’accord. Il examine aussi les types de relations qui existent entre les différents éléments des numéraux composés.
Sacrement de mariage et miséricorde de Dieu
Authors: Bordeyne Philippe 
Published: February 2015

Peut-on résoudre les problèmes pastoraux soulevés par les échecs conjugaux en faisant appel à la miséricorde divine ? Cette question disputée laisse souvent de côté le fait que le sacrement de mariage peut être pensé théologiquement à la lumière de la miséricorde de Dieu. Dans l’encyclique Dives in misericordia , saint Jean-Paul II voit dans la révélation le point culminant de la miséricorde divine. Tant la théologie biblique que la configuration actuelle des liens amoureux conduisent à interpréter l’entrée dans le mariage comme l’événement d’une rencontre personnelle avec le Dieu miséricordieux et comme un engagement à pratiquer la miséricorde en réponse à son amour. Cette double perspective peut inspirer la préparation au mariage et la pastorale familiale. Elle permet également de placer les échecs apparents tout autant que les réussites sous la lumière inaugurale de la miséricorde divine. Celle-ci a le pouvoir de réintroduire de la continuité dans les histoires humaines souvent marquées par les accrocs et les ruptures.
PRL-3 Mediates the Protein Maturation of ULBP2 by Regulating the Tyrosine Phosphorylation of HSP60
Authors: Leung Wai-Hang , Vong Queenie P. , Lin Wenwei , Bouck David , Wendt Susanne , Sullivan Erin , Li Ying , Bari Rafijul , Chen Taosheng , Leung Wing 
Published: February 2015

Abstract
Many malignant cells release the NKG2D ligand ULBP2 from their cell surface to evade immunosurveillance by NK cells and CD8 T cells. Although the shedding mechanism remains unclear, various inhibitors of matrix metalloproteinases have been shown to efficiently block the release of soluble ULBP2. The clinical use of these inhibitors, however, is limited because of adverse side effects. Using high-throughput screening technique, we identified a specific inhibitor of phosphatase of regenerating liver 3 (PRL-3) that could reduce the level of soluble ULBP2 in the culture supernatant of various cancer cell lines. Inhibition or gene knockdown of PRL-3 did not reduce ULBP2 shedding, but rather suppressed posttranslational maturation of ULBP2, resulting in intracellular retention of immature ULBP2. We then found that ULBP2 was constitutively associated with heat shock protein HSP60. Complete maturation of ULBP2 required tyrosine phosphorylation of HSP60 which was mediated by PRL-3.
Transient Blockade of Delta-like Notch Ligands Prevents Allograft Rejection Mediated by Cellular and Humoral Mechanisms in a Mouse Model of Heart Transplantation
Authors: Wood Sherri , Feng Jiane , Chung Jooho , Radojcic Vedran , Sandy-Sloat Ashley R. , Friedman Ann , Shelton Amy , Yan Minhong , Siebel Christian W. , Bishop D. Keith , Maillard Ivan 
Published: February 2015

Abstract
Rejection remains a major clinical challenge limiting allograft survival after solid organ transplantation. Both cellular and humoral immunity contribute to this complication, with increased recognition of Ab-mediated damage during acute and chronic rejection. Using a mouse model of MHC-mismatched heart transplantation, we report markedly protective effects of Notch inhibition, dampening both T cell and Ab-driven rejection. T cell–specific pan-Notch blockade prolonged heart allograft survival and decreased IFN-γ and IL-4 production by alloreactive T cells, especially when combined with depletion of recipient CD8+ T cells. These effects were associated with decreased infiltration by conventional T cells and an increased proportion of regulatory T cells in the graft. Transient administration of neutralizing Abs specific for delta-like (Dll)1/4 Notch ligands in the peritransplant period led to prolonged acceptance of allogeneic hearts, with superior outcome over Notch inhibition only in T cells. Systemic Dll1/4 inhibition decreased T cell cytokines and graft infiltration, germinal center B cell and plasmablast numbers, as well as production of donor-specific alloantibodies and complement deposition in the transplanted hearts. Dll1 or Dll4 inhibition alone provided partial protection. Thus, pathogenic signals delivered by Dll1/4 Notch ligands early after transplantation promote organ rejection through several complementary mechanisms. Transient interruption of these signals represents an attractive new therapeutic strategy to enhance long-term allograft survival.
Histone Lysine Methyltransferase Ezh1 Promotes TLR-Triggered Inflammatory Cytokine Production by Suppressing Tollip
Authors: Liu Yiqi , Zhang Qian , Ding Yuanyuan , Li Xia , Zhao Dezhi , Zhao Kai , Guo Zhenhong , Cao Xuetao 
Published: February 2015

Abstract
Histone modifications play critical roles in the regulation of gene expression; however, their roles in the regulation of the innate response remain to be fully investigated. Using transcriptome analysis of mouse immature dendritic cells (DCs) and LPS-induced mature DCs, we identified that Ezh1 was the most upregulated histone methyltransferase during DC maturation. In this study, we investigated the role of Ezh1 in regulating the innate immune response. We found that silencing of Ezh1 significantly suppressed TLR-triggered production of cytokines, including IL-6, TNF-α, and IFN-β, in DCs and macrophages. Accordingly, TLR-activated signaling pathways were impaired in Ezh1-silenced macrophages. By transcriptome analysis of Ezh1-silenced macrophages, we found that Toll-interacting protein (Tollip), one well-known negative regulator of TLR signaling, was upregulated. Silencing of Tollip rescued TLR-triggered cytokine production in Ezh1-silenced macrophages. The SET domain of Ezh1 is essential for its enhancing effect on the TLR-triggered innate immune response and downstream signaling, indicating that Ezh1 promotes a TLR-triggered innate response through its lysine methyltransferase activity. Finally, Ezh1 was found to suppress the transcription of Tollip by directly targeting the proximal promoter of tollip and maintaining the high level of trimethylation of histone H3 lysine 27 there. Therefore, Ezh1 promotes TLR-triggered inflammatory cytokine production by suppressing the TLR negative regulator Tollip, contributing to full activation of the innate immune response against invading pathogens.
SHIP1 Intrinsically Regulates NK Cell Signaling and Education, Resulting in Tolerance of an MHC Class I–Mismatched Bone Marrow Graft in Mice
Authors: Gumbleton Matthew , Vivier Eric , Kerr William G. 
Published: February 2015

Abstract
NK cells are an important component of host immune defense against malignancy and infection. NK cells are educated by MHC class I ligands to ensure self-tolerance while also promoting lytic competency against altered self and damaged self targets. However, the intracellular molecular events that culminate in tolerance and functional competency of educated NK cells remain undefined. Mice with germline deficiency in SHIP1 were shown to have a defective NK cell compartment. However, SHIP1 is expressed in all hematopoietic lineages, and consequently several hematolymphoid phenotypes have already been identified in certain cell types that are the result of SHIP1 deficiency in cells in separate and distinct lineages, that is, cell-extrinsic phenotypes. Thus, it was previously impossible to determine the NK cell–intrinsic role of SHIP1. In the present study, through the creation of an NK cell–specific deletion mouse model of SHIP1, we show that SHIP1 plays a profound NK lineage–intrinsic role in NK cell homeostasis, development, education, and cytokine production. Moreover, we show SHIP1 expression by NK cells is required for in vivo–mismatched bone marrow allograft rejection as well as for NK memory responses to hapten.
Osteolytic bone lesions – A rare presentation of AML M6.
Authors: N. Geetha , KP Sreelesh , Jacob Priya Mary , VS Lali , Nair Rekha A 
Published: February 2015

Acute myeloid leukemia (AML) M6 is a rare form of AML accounting for < 5 % of all AML. Extramedullary involvement is very rarely seen in this entity. Skeletal lesion has not been described in AML M6 before. We discuss the case of a 17 year old boy with AML M6 who presented with osteolytic lesion of right humerus. He was treated with induction and consolidation chemotherapy. The present case is the first report in literature of AML M6 presenting with skeletal lesions.
INFLUENCE OF STRAIN AMPLIFICATION NEAR CRACK TIP ON THE FRACTURE RESISTANCE OF CARBON BLACK–FILLED SBR
Authors: Liu Chang , Dong Bin , Zhang Li-Qun , Zheng Qiang , Wu You-Ping 
Published: February 2015

ABSTRACT
Singularity of strain field at the crack tip of elastomeric material has recently attracted considerable attention. For SBR filled with four different types of carbon black, the strain distribution at the crack tip of the single-edge notched tension specimens are investigated using digital image correlation (DIC) and finite element analysis (FEA). Both DIC and FEA results demonstrate that the larger the carbon black particle size, the less strain amplification at the crack tip of SBR. However, the strain amplification region obtained from FEA simulation is much smaller than the strain amplification observed from DIC, and the reasons are discussed. Critical J-integral (JIC) and tearing modulus (TR) are calculated via J-integral method and are connected to crack initiation and propagation resistance of the SBR, respectively. With increasing carbon black particle size, both JIC and TR decrease. Similar trends also occur for tearing energy deduced from the dynamic mechanical thermal analysis. These results are in agreement with the prediction based on strain amplification at the crack tip.
Selective Solid-Phase Extraction of Zinc(II) from Environmental Water Samples Using Ion Imprinted Activated Carbon
Authors: Moniri Elham , Panahi Homayon Ahmad , Aghdam Khaledeh , Sharif Amir Abdollah Mehrdad 
Published: February 2015

Abstract
A simple ion imprinted amino-functionalized sorbent was synthesized by coupling activated carbon withiminodiacetic acid, a functional compound for metal chelating, through cyanoric chloride spacer. The resulting sorbent has been characterized using FTIR spectroscopy, elemental analysis, and thermogravimetricanalysis and evaluated for the preconcentration and determination of trace Zn(II) in environmental watersamples. The optimum pH value for sorption of the metal ion was 6–7.5. The sorption capacity of the functionalized sorbent was 66.6 mg/g. The chelating sorbent can be reused for 10 cycles of sorption-desorption without any significant change in sorptioncapacity. A recovery of 100% was obtained for the metal ion with 0.5 M nitric acid as the eluent. Compared with nonimprinted polymer particles, the preparedZn-imprinted sorbent showed high adsorption capacity, significant selectivity, and good site accessibility for Zn(II). Scatchard analysis revealed that the homogeneous binding sites were formed in the polymer. The equilibrium sorption data of Zn(II) by modified resin were analyzed by Langmuir, Freundlich, Temkin, and Redlich-Peterson models. Based on equilibriumadsorption data, the Langmuir, Freundlich, and Temkin constants were determined as 0.139, 12.82, and 2.34, respectively, at 25°C.
Determination of V, Cr, Cu, As, and Pb Ions in Water and Biological Samples by Combining ICP-MS with Online Preconcentration Using Impregnated Resin
Authors: Wang Shuo , Dong Xv , Dai Bingye , Pan Mingfei , He Shaoyuan , Wang Junping 
Published: February 2015

Abstract
A method was developed for detection of V, Cr, Cu, As, and Pb in water and biological samples by combining online flow injection and preconcentration with inductively coupled plasma-MS. The 2-nitroso-1-naphthol-4-sulfonic acid (Nitroso-S) impregnated MCI GEL CHP20P resin was prepared as an enrichment sorbent. Some parameters affecting the efficiency of the preconcentration process were investigated in the experiment, including the pH and volume of sample solution, the flow rate for sample loading, the type and concentration of eluent, and the influence of co-existing ions. Under the optimal experimental conditions, the enrichment factor and LOD (3s) of chosen metal ions V, Cr, Cu, As, and Pb were in the ranges of 71–268 and 4.89–23.76 ng/L, respectively. Based on 11 repeated measurementsof standard solutions (1.0 μg/L), the RSD ofthe ions ranged from 1.2 to 2.9%. The detection procedure was also performed for analyzing two certifiedreference materials, GBW 08607 (water) and GBW 10052 (green tea), as well as environmental water and biological samples. Good agreement with certified valuesand high recoveries have demonstrated improved accuracy of the proposed method.
Application of Near Infrared Spectroscopy Coupled with Fluidized Bed Enrichment and Chemometrics to Detect Low Concentration of β-Naphthalenesulfonic Acid
Authors: Li Wei , Zhang Xuan , Zheng Kaiyi , Du Yiping , Cap Peng , Sui Tao , Geng Jinpei 
Published: February 2015

Abstract
A fluidized bed enrichment technique was developed to improve sensitivity of near infrared (NIR) spectroscopy with features of rapidness and large volumesolution. D301 resin was used as an adsorption material to preconcentrate β-naphthalenesulfonic acid in solutions in a concentration range of 2.0–100.0 μg/mL, and NIR spectra were measured directly relative to the β-naphthalenesulfonic acid adsorbed on the material. An improved partial least squares (PLS) model was attained with the aid of multiplicative scatter correction pretreatmentand stability competitive adaptive reweighted sampling wavenumber selection method. The root mean squareerror of cross validation was 1.87 μg/mL at PLS factor of 7. An independent test set was used to assess the model, with the relative error (RE) in anacceptable range of 0.46 to 10.03% and mean RE of 3.72%. This study confirmed the viability of the proposed method for the measurement of a low content of β-naphthalenesulfonic acid in water.
Multi-residue Determination of Polar Veterinary Drugs in Livestock and Fishery Products by Liquid Chromatography/Tandem Mass Spectrometry
Authors: Kanda Maki , Nakajima Takayuki , Hayashi Hiroshi , Hashimoto Tsuneo , Kanai Setsuko , Nagano Chieko , Matsushima Yoko , Tateishi Yukinari , Yoshikawa Soichi , Tsuruoka Yumi , Sasamoto Takeo , Takano Ichiro 
Published: February 2015

Abstract
Residues of 37 polar veterinary drugs belonging to six families (quinolones, tetracyclines, macrolides, lincosamides, sulfonamides, and others) in livestock and fishery products were determined using a validated LC-MS/MS method. There were two key points insample preparation. First, extraction was performed with two solutions of different polarity. Highly polar compounds were initiallyextracted with Na2EDTA-McIlvaine's buffer (pH 7.0). Medium polar compounds were then extracted from the same samples with acetonitrile containing 0.1% formic acid. Secondly, cleanup was performed using a single SPE polymercartridge. The first extracted solution was applied to the cartridge. Highly polar compounds were retained on the cartridge. Then, the second extracted solution was applied to the same cartridge. Both highly and medium polar compounds were eluted from the cartridge. This method satisfied the guideline criteria for 37 out of 37 drugs in swine muscle, chicken muscle, bovine muscle, prawn, salmon trout, red sea bream, milk, and honey; 35 out of 37 in egg; and 34 out of 37 in flounder. The LOQ ranged from 0.1 to 5 μg/kg. Residues were detected in 24 out of 110 samples and analyzed using the validated method.
Orphée et l’orphisme dans À la recherche du temps perdu de Marcel Proust
Authors: Turmel Émilie 
Published: February 2015

Plusieurs études ont été menées dans le but de déterminer la signification des allusions mythologiques dans le roman À la recherche du temps perdu de Marcel Proust. Certaines d’entre elles se sont particulièrement intéressées au mythe d’Orphée et à sa résonnance singulière dans l’imaginaire proustien. Mais peu de spécialistes ont questionné les influences du mouvement religieux associé à ce poète légendaire : l’orphisme. Proust n’est pas le seul auteur à s’être réapproprié le mythe orphique ; les tenants du romantisme et du symbolisme en ont fait une véritable figure de proue. L’auteur de la Recherche possède l’avantage, à l’orée de la modernité, de pouvoir embrasser leurs visions et d’y sélectionner soigneusement ce qui correspond à son dessein esthétique. Mais ce dessein est-il expressément orphique ? Pour le savoir, nous nous proposons de revisiter l’oeuvre de Proust en examinant les sources antiques et les inspirations contemporaines ayant alimenté l’intérêt de ce dernier pour la figure d’Orphée ainsi que pour le culte mystique qui y est associé. Nous exposerons ensuite la sélection que Proust opère à travers ces matières premières dans le but de dégager le sens qu’il attribue à son adaptation personnelle de la légende d’Orphée. Subséquemment, nous pourrons vérifier si cette interprétation est cohérente ou non avec les préceptes religieux historiquement attribués au poète mythique. Ainsi, nous saurons si des schèmes orphiques sous-tendent réellement la création narrative de Proust.
Geothermal Resources and Technology: Introduction
Authors: Blair Peter D. 
Published: February 2015

AbstractGeothermal resources are traditionally divided into the following three basic categories or types: 1. Hydrothermal convection systems, which include thermal aquifers that are so‐called vapor‐dominated or liquid‐dominated systems. 2. Hot igneous resources, which include hot dry rock and geologic magna systems. 3. Conduction‐dominated resources, which include geopressured and radiogenic resources. This chapter discusses provisional estimates of the power generation potential of a number of unconventional resource locations in Arizona, California, Colorado, Idaho, Montana, Nevada, New Mexico, Oregon, Utah, Washington, and Wyoming that are potentially suitable for so‐called Enhanced Geothermal Systems (EGS) technology. A variety of technologies are in current use to convert geothermal energy to useful forms. These can very generally be grouped into three basic categories: (1) direct use, (2) electric power generation, and (3) geothermal heat pumps. Each category utilizes the geothermal resource in a very different way.