bluuebunny/crossref_metadata_2025_split huggingface dataset:
AVALIAÇÃO NEUROBIOLOGICA DO USO DA RITALINA EM PACIENTES NÃO PORTADORES DE TDHA
Authors: Neto João Pereira da Costa , Lopes Giselly Sales Tizolin , Melo Samille Menezes , Viana Lucas Furtado , Costa Maria Eduarda Gomes Oliveira , Lobo Victor Bezerra , Sousa Bruna Carla Saboia , Fernandes Íris Machado , Costa Anna Júlia Matos , Melo Mirla de Araújo , Lima Júlia Malena Andrade , Peixoto Raphael Nunes Cavalcanti , Lima Sebastião Willo Abreu , Silva Sarah Lucia de Sousa , Santos Allison Luz , Pedrosa Gabriel de Albuquerque , Evangelista Daniel Martins , Lourenço Gislayne Fontenele Albuquerque , Filho Francisco Demontiez Prado Arrua , Aguiar Yan Prado , Evangelista Nayme Martins , Moreira Livia Chagas , Tomaz Ana Sabrina Braz , Balbino Thaís Torres , Parente Thyrso Moreira , Leão Marcelo Novais de Arêa , Cortez Natanael Veras , Albuquerque Emanuel Davi Braga Leite , Fontenele Davi Viana Souza , Filomeno Angelita Heloina Fonteles Castro Lima , Estevam Pedro Henrique de Sousa Pinheiro 
Published: July 2024

O uso não terapêutico da Ritalina, ou metilfenidato, entre indivíduos sem Transtorno de Déficit de Atenção e Hiperatividade (TDAH) tem aumentado, principalmente em ambientes acadêmicos, devido ao seu potencial para melhorar a atenção e o desempenho cognitivo. Este estudo revisa os efeitos neurobiológicos desse uso em indivíduos sem TDAH. Foram comparadas as alterações na atividade cerebral, especialmente no córtex pré-frontal e sistema límbico, investigadas mudanças na neurotransmissão dopaminérgica e avaliadas as diferenças no desempenho neuropsicológico antes e após o uso da Ritalina. A revisão incluiu artigos publicados entre 2011 e 2024 nas bases PubMed, SciELO, LILACS e Google Scholar, focando nos efeitos neurobiológicos da Ritalina em indivíduos sem TDAH. Resultados indicam que, apesar de melhorias temporárias na concentração e memória de trabalho, o uso prolongado pode causar ansiedade, taquicardia, alterações no apetite e dependência, além de reduzir a eficácia do medicamento devido à tolerância. Conclui-se que os riscos à saúde física e mental superam os benefícios cognitivos de curto prazo. É essencial conscientizar sobre os perigos do uso não prescrito da Ritalina e promover alternativas saudáveis para o aprimoramento cognitivo, além de desenvolver diretrizes baseadas em evidências para minimizar os riscos do uso não supervisionado de estimulantes.
KUDUS ISLAMIC CENTER DENGAN PENDEKATAN ARSITEKTUR REGIONALISME
Authors: Indriani Rani , Hartanto Tri , Prabowo Wahyu 
Published: July 2024

Indonesia adalah negara yang mempunyai masyarakat yang beranekaragam, baik keragamaan organisasi, sejarah, budaya, adat istiadat dan sebagainya. Dukcapil Kementrian Dalam Negeri mencatat, terdapat 238,09 juta jiwa atau 86,93% penduduk Indonesia yang tercatat beragama Islam pada tahun 2021. Kudus merupakan salah satu pusat perkembangan Islam di Pulau Jawa dan sebagian besar penduduk Kabupaten Kudus menganut ajaran Islam. Kudus dikenal sebagai Kota Wali. Dibuktikan dengan adanya banggunan sejarah peninggalan Wali yaitu Masjid Menara Kudus, dan terdapat dua makam Wali yaitu makam Sunan Kudus dan Sunan Muria yang sering dikunjungi umat Islam di Jawa. Berdasarkan Badan Pusat Statistik Pertumbuhan penduduk beragama Islam di Kudus sangat berkembang pesat. Berdasarkan kondisi tersebut Perencanaan dan Perancangan Kudus Islamic Center dengan pendekatan Arsitektur Regionalisme sangat mendukung dalam menopang perkembangan pariwisata di kabupaten Kudus dan dapat memberikan wadah bagi Masyarakat dalam mengembangkan dan mengkaji keagamaan, serta dapat bersosialisasi, dan mengenal budaya atau sejarah perkembangan Islam khususnya Kabupaten Kudus. Tujuan dari perencanaan dan perancangan Kudus Islamic Center yaitu sebagai wadah perkembangan Islam dan penopang perkembangan pariwisata religi di kabupaten Kudus. Metode penelitian yang digunakan dalam perencanaan dan perancangan ini menggunakan metode deskriptif kualitatif. Hasil penelitian telah mendapatkan suatu konsep perencanaan dan perancangan Kudus Islamic Center dengan Pendekatan Arsitektur Regionalisme.
FASILITAS PEJALAN KAKI UNTUK DIFABEL PADA JALUR PEDESTRIAN JALAN SLAMET RIYADI SURAKARTA SISI SELATAN
Authors: Rakhmanty Febrione Putri 
Published: July 2024

Jalur pedestrian memiliki peran penting dalam menghubungkan dan mendukung kinerja ruang kota. Jalur pejalan kaki menuju halte dan halte bus telah didesain ulang dan ditingkatkan agar dapat diakses oleh penyandang disabilitas juga. Rute pejalan kaki menuju halte dan halte bus telah dirancang ulang dan diperbaiki agar lebih mudah diakses oleh penyandang disabilitas. Peran aksesibilitas dapat memberikan kenyamanan dengan memenuhi kebutuhan dan kemampuan penyandang disabilitas intelektual dan kognitif, serta penyandang disabilitas fisik dan penglihatan, serta kebutuhan dan kemampuan orang lanjut usia, ibu hamil, bayi, dan anak kecil. Salah satu jalur pedestrian yang ada di Kota Surakarta adalah jalur pedestrian di Jalan Slamet Riyadi Surakarta yang diharapkan dapat memberikan kenyamanan dan persamaan hak bagi seluruh pengguna jalan. Berdasarkan hasil analisa dan observasi lapangan yang telah dilakukan terhadap jalur pedestrian di Jalan Slamet Riyadi Surakarta sisi selatan masih belum dapat dimanfaatkan secara optimal karena kurang dapat memenuhi faktor keamanan bagi pengguna dengan disabilitas.
PELATIHAN INTEGRASI ICT PADA FITUR E-LEARNING BAGI DOSEN FKIP UNIVERISTAS CENDERAWASIH
Authors: Nurbaya  , Hanida Listian  , Suriyah Satar  , Tiffany Shahnaz Rusli  , Agnes Teresa Panjaitan  , Rio Wakhid Hujjatul Islam  
Published: July 2024

Integrasi ICT dalam proses pembelajaran merupakan salah satu karakteristik meningkatnya kualitas pendidikan. Penggunaan LMS oleh dosen dalam proses pembelajaran adalah cara efektif integrasi digital teknologi untuk meningkatkan kompetensi ICT mahasswa. Keharusan dosen dalam mengaplikasikan LMS dalam proses perkuliahan menuntut mereka untuk menguasai fitur-fitur yang ada pada platform E-Learning yang dikembangkan oleh Tim IT universitas Cenderawasih. Tujuan utama diadakannya pelatihan ini adalah meningkatkan pemahaman para dosen di lingkungan FKIP Universitas Cenderawasih terhadap fitur LMS yang akan diaplikasikan dalam proses pembelajaran. Pelatihan ini berlangsung dalam 4 tahap kegiatan, yaitu 1) Pembentukan tim IT oleh FKIP Universitas Cenderawasih sebagai narasumber; 2) Pemaparan materi oleh narasumber; 3) Demonstrasi LMS olleh dosen dan narasumber; dan 4) Evaluasi kegiatan pelatihan. Hasil dari pelatihan adalah seluruh peserta pelatihan dosen yang hadir, sebanyak 150 orang, telah mengetahui fitur-fitur pada LMS yang akan digunakan dalam perkuliahan. Diharapkan pelatihan ini tidak hanya dilakukan kepada dosen di Lingkungan FKIP Universitas Cenderawasih, tetapi juga di sekolah-sekolah yang ada di Kota Jayapura. Hal ini untuk meningkatkan literasi digital yang turut digalakkan oleh pemerintah dalam Kurikulum Merdeka Belajar – Kampus Merdeka.
STRATEGI MAHASISWA DALAM MENINGKATKAN MOTIVASI BELAJAR AL-QUR’AN ANAK DI TPA
Authors: Jumahir Jumahir , Hasna Koba’a  , Lamadang Karmila , Aminullah Muhammad Rizky 
Published: July 2024

Di indonesia pendidikan sangat dibutuhkan untuk masa depan, sehingga pembelajaran sejak kanak-kanak harus diprioriraskan, bukan hanya pembelajaran umum yang harus utamakan melaikan pembelajaran mengaji sejak kenak-kanak harus dijalankan sehingga pemebelajran mengaji harus memerlukan strategi guna meningkatkan motivasi anak anak di TPA ibu suryati di Desa Mina Karya Kecamatan Moilong Kabupaten Banggai Sulawesi Tenggah untuk belajar. Kemampuan membaca huruf hijaiyah yang diteliti adalah membaca huruf hijaiyah secara acak dan membedakan huruf hijaiyah yang bentuknya hampir mirip. Hasil ysng di diharapkan anak –Anak mampu membaca huruf hijaiyah dengan benar, sehingga tidak hanya dengan pendampingan mengaji, akan tetapii mengguakan metode Tahsin, agar anak-anak dapat membaca al quran dengan kaidah-kaidah hukum tajwid, metode yang digunakan bertujuan untuk memperbaiki bacaan al quran membaguskan, atau menjadikan lebih baik daripada sebelumnya karena hasil penelian membuktikan bawahsannya anak-anak masi banyak tidak mengetahui tentang kaidah-kaidah hukum tajwid sehingga metode tahsin sangat bermanfaat dalam pendampingan mengaji pada anak-anak.
The impact of a company ownership structure on managing airport functions
Authors: Sperka-Cieciura Alina 
Published: July 2024

This study analyses the problems of privatisation in the aviation industry by comparing airport ownership structures. In the context of the global perspective, this study focuses on airports located in the EU. Due to the supremacy of EU law over national legal systems, these airports function in a comparable legal environment. The analysis considered the following as main airport functions: investment capacity, environmental impact, public service provision, and ensuring security. The EU law refers to all entities regardless of their ownership structure and location. Moreover, public financing is submitted to provisions concerning state aid. This article shows that ownership structure does not influence airport functions. There are several regulations granting this, and the case study of ECJU rulings has proved that these regulations are effective. Their effectiveness for the future, if the participation of private capital increases, should be the subject of further auditing. From this study arises the question of the effects of possible deregulation of the aviation market. This study can potentially help aviation industries look at ownership issues, specifically those of airports, through the perspective of regional, public welfare, and local economy. This changes the motivation of airports as nodes of global commute from a local perspective. It is also a voice in the discussion about the consequences of possible privatisation in the aviation market.
Poly Lactic-co-Glycolic Acid Nanoparticles: Flow Rates and Gauge Sizes Influence the Droplet Surface Tension and Particle Sizing
Authors: Shakri Adibah , Ikmal Shawaludin Muhammad Ayman , Mohamed Suffian Izzat Fahimuddin , Farikhah Irna , Mohd Pa’ad Khairunnisa 
Published: July 2024

Electrospray is a novel and versatile approach to the synthesis of nanosized particles. In this paper, the effects of electrospray process parameters such as gauge size (18 G-25 G) and flow rate (0.9-1.5 ml hr-1) on droplet surface tension and electrospray particle size were evaluated. 25 mg Poly Lactic-co-Glycolic Acid (PLGA) were dissolved in 100 ml acetone before being subjected to electrospray. Tate’s Law was used to calculate the surface tension while the Malvern nanosizer was used to measure the particle size. Based on Tate’s Law calculation, when the gauze size increased from 18 G-25 G, the droplet surface tension increased from 10.07 Nm-1 to 18.17 Nm-1 showing a direct pattern. At the same time, the flowrate is inversely proportional to droplet surface tension. When the flow rate increased from 0.9-1.5 ml hr-1, the droplet surface tension was reduced. This is due to the increasing ratio of vicious force and surface tension. For particle size, as surface tension increased from 10.07 Nm-1 to 18.17 Nm-1, particle size increased from 205.57 nm to 612 nm owing to the corona discharge producing larger progeny droplets that chain into smaller particles through coulomb fission as more charge is required to overcome the surface tension. In conclusion, flow rate and gauge size influenced the surface tension thus affecting the nanosized particles.
Solar Coronal Heating by Kinetic Alfvén Waves
Authors: Ayaz Syed , Li Gang , Khan Imran A. 
Published: July 2024

Abstract
The utilization of the Cairns distribution serves as a vital tool for characterizing the nonthermal attributes commonly observed in space plasmas. In these intricate plasma environments, extensive measurements have been conducted to monitor the fluctuations inherent in the perturbed electromagnetic (EM) field and the associated Poynting flux, specifically concerning kinetic Alfvén waves (KAWs). Traditionally, these fluctuations have been attributed to gyroradius correction terms within the framework of Maxwellian distributed plasmas. However, our study introduces an innovative perspective grounded in kinetic theory coupled with the Cairns distribution, adept at encapsulating the nonthermal nuances characterized by the index parameter Λ. Within the domain of the solar corona, our investigation centers on the perturbed EM field ratios and the Poynting flux of KAWs, with a foundation in the Cairns distribution function. It is noteworthy that the perpendicular components, although deemed less significant due to the dominance of k
⊥ over k
∥, remain unquantified regarding their relative insignificance. Similarly, the exploration of the imaginary part of the normalized EM field ratio has been a relatively understudied domain. Furthermore, we delve into the nuanced assessment of the power rate I

x
/I

z
characterizing the perpendicular and parallel normalized Poynting fluxes (S

x
and S

z
). Intriguingly, we discern that large values of Λ, compared to their Maxwellian counterparts, manifest advantageous attributes, particularly concerning the energization of the plasma over extended distances along the ambient magnetic field lines. The analytical insights gleaned from this study find practical application in understanding phenomena within the solar atmosphere, particularly shedding light on the significant role played by nonthermal particles in the observed heating processes.
Activin A Promotes Differentiation of a Pathogenic Multicytokine IL-9-secreting CD4+ T Cell Population
Authors: Ulrich Benjamin J , Zhang Wenwu , Kenworthy Blake T , Kharwadkar Rakshin , Olson Matthew R , Kaplan Mark H 
Published: July 2024

Abstract
The development of Th subsets results from cellular and cytokine cues that are present in the inflammatory environment. The developing T cell integrates multiple signals from the environment that sculpt the cytokine-producing capacity of the effector T cell. Importantly, T cells can discriminate similar cytokine signals to generate distinct outcomes, and that discrimination is critical in Th subset development. IL-9-secreting Th9 cells regulate multiple immune responses, including immunity to pathogens and tumors, allergic inflammation, and autoimmunity. In combination with IL-4, TGF-β or activin A promotes IL-9 production; yet, it is not clear if both TGF-β family members generate Th9 cells with identical phenotype and function. We observed that in contrast to TGF-β that efficiently represses Th2 cytokines in murine Th9 cultures, differentiation with activin A produced a multicytokine T cell phenotype with secretion of IL-4, IL-5, IL-13, and IL-10 in addition to IL-9. Moreover, multicytokine secreting cells are more effective at promoting allergic inflammation. These observations suggest that although TGF-β and IL-4 were identified as cytokines that stimulate optimal IL-9 production, they might not be the only cytokines that generate optimal function from IL-9-producing T cells in immunity and disease.
Insight into Body Mass Index among School Students during the COVID-19 Pandemic
Authors: Alfaleh Amjad , Alkattan Abdullah , Almutairi Fatemah , Almutairi Mona , Sagor Khlood , Abdulhai Mody , Alageel Alaa , Alabdulkareem Khaled 
Published: July 2024

Abstract

Background:
Several reports indicate that extended stay at home for online school as a result of the coronavirus disease 2019 (COVID-19) pandemic or other reasons may change the normal physical activity and body weight of school-age students. Previous studies revealed that almost 50% of school students complained of an increase or decrease of more than 3 kg of weight due to lower physical activity. This study aims to provide an insight into the body mass index (BMI) of school students during the COVID-19 pandemic.

Methods:
A retrospective matched-longitudinal study was conducted in 2022 based on previous data on the BMI-for-age percentile in school students aged 6–18 years. These data were collected the year before and during the COVID-19 pandemic (2019–2021).

Results:
All the included students were Arabic (n = 53,580) and were not diagnosed with chronic illnesses. The outcomes showed that the overall percentage of students with normal weight was 54%, 56%, and 53% during 2019–2021 years, respectively. The frequencies of students with optimal BMI increased significantly in 2020 compared to 2019 (P < 0.01); however, there was no statistical significance with regard to normal body weight trends (P > 0.05) between 2019 and 2021. Overweight among students increased during the COVID-19 pandemic (2020–2021), as almost 10% of the students were overweight in 2019 compared to 12% in 2020 and 2021 (P < 0.01). In addition, obese students increased in 2020–2021 compared to 2019 (15–17% vs. 10%, P < 0.01). In contrast, underweight trends among students declined from 26% reported in 2019 compared to 17–18% in 2020 and 2021 (P < 0.01).

Conclusion:
There are significant variations in Arabic school-age students regarding their BMI values. Obesity was highly detected among children and adolescents during the COVID-19 pandemic years compared to that in 2019, while underweight cases declined.
Viral Infections as the most Frequent Causes of Undifferentiated Fever in Children Living in the Lower Mekong Region: A Systematic Review
Authors: Tran Xuan Duong , Dao Thi Loi , Nguyen Nhu Ngoc , Hoang Van Thuan , Gautret Philippe 
Published: July 2024

AbstractTo summarize common infections responsible for undifferentiated fever in children living in the lower Mekong region. This review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. Eighteen articles were included, including eight studies that were performed on both children and adults. A total of 1,017,923 patients were included in these studies, and viral infections were the most common causes of infections. Dengue virus was detected in 6%–72.8% of the patients, chikungunya virus in 15.8%–66.0% of the patients, and influenza A virus in 3.8%–18.8% of the patients.Rickettsia sp. was detected in 0%–18.9% of the patients,Leptospirawas detected in 0%–27.2% of the patients, andSalmonella typhiin 2.6%–37.5% of the patients. Viral fever is the most common cause of undifferentiated fever among children in the lower Mekong region. Testing for microbial pathogens may help reduce inappropriate antibiotic use.
The Utility of Artificial Intelligence and Machine Learning in the Diagnosis of Takotsubo Cardiomyopathy: A Systematic Review
Authors: Huang Helen , Perone Francesco , Leung Keith Sai Kit , Ullah Irfan , Lee Quinncy , Chew Nicholas , Liu Tong , Tse Gary 
Published: July 2024

Abstract

Introduction:
Takotsubo cardiomyopathy (TTC) is a cardiovascular disease caused by physical/psychological stressors with significant morbidity if left untreated. Because TTC often mimics acute myocardial infarction in the absence of obstructive coronary disease, the condition is often underdiagnosed in the population. Our aim was to discuss the role of artificial intelligence (AI) and machine learning (ML) in diagnosing TTC.

Methods:
We systematically searched electronic databases from inception until April 8, 2023, for studies on the utility of AI- or ML-based algorithms in diagnosing TTC compared with other cardiovascular diseases or healthy controls. We summarized major findings in a narrative fashion and tabulated relevant numerical parameters.

Results:
Five studies with a total of 920 patients were included. Four hundred and forty-seven were diagnosed with TTC via International Classification of Diseases codes or the Mayo Clinic diagnostic criteria, while there were 473 patients in the comparator group (29 of healthy controls, 429 of myocardial infarction, and 14 of acute myocarditis). Hypertension and smoking were the most common comorbidities in both cohorts, but there were no statistical differences between TTC and comparators. Two studies utilized deep-learning algorithms on transthoracic echocardiographic images, while the rest incorporated supervised ML on cardiac magnetic resonance imaging, 12-lead electrocardiographs, and brain magnetic resonance imaging. All studies found that AI-based algorithms can increase the diagnostic rate of TTC when compared to healthy controls or myocardial infarction patients. In three of these studies, AI-based algorithms had higher sensitivity and specificity compared to human readers.

Conclusion:
AI and ML algorithms can improve the diagnostic capacity of TTC and additionally reduce erroneous human error in differentiating from MI and healthy individuals.
Enhancing Palliative Care for Deep Vein Thrombosis: A Scoping Review with Clinical Insights on the Integration of Physical Activity
Authors: Sharma Abhishek , Chahal Aksh , Sharma Nidhi 
Published: July 2024

Abstract

Objective:
This review aims to explore the role of physical activity as an integral palliative care strategy in managing deep vein thrombosis (DVT), providing a comprehensive analysis and practical insights for clinicians.

Methods:
A thorough review of relevant literature was conducted, encompassing studies, clinical trials, and expert opinions that examine the relationship between physical activity and palliative care from the perspective of DVT. The search included databases such as PubMed, PEDro, and Scopus, with an emphasis on articles published within the last decade.

Results:
The review highlights the multifaceted benefits of incorporating physical activity into the palliative care approach for individuals with DVT. Physical activity has been effective in enhancing overall well-being, alleviating symptoms, and contributing to the holistic management of DVT-related complications. In addition, the literature underscores the importance of personalized exercise regimens tailored to the patient’s condition, ensuring safety and effectiveness.

Conclusion:
This comprehensive review underscores the significance of physical activity as a pivotal element in palliative care for individuals with DVT. Integrating personalized exercise regimens into the management strategy offers a holistic approach that addresses the physical and psychosocial aspects of DVT. As clinicians navigate the complexities of DVT palliative care, a thorough and timely incorporation of physical activity can significantly contribute to enhancing the overall quality of life for affected individuals.
Sleep quality and glycemic control in adults with type 2 diabetes mellitus
Authors: Borzouei Shiva , Ahmadi Asma , Pirdehghan Azar 
Published: July 2024

ABSTRACTAim:Type 2 diabetes mellitus (T2DM) is a common disease that imposes a substantial burden on the healthcare system and patients. Lifestyle modification such as sleep hygiene plays a crucial role in glycemic control. Sleep disorders impact many aspects of health. In this study, we aimed to investigate the correlation between sleep quality and glycemic control in T2DM. Method: This cross-sectional study was performed on 163 T2DM patients, attending Shahid Beheshti Hospital in Hamadan, Iran from March 2020 to 2021. Besides recording the demographic data and HbA1c level of participants, they were asked the Pittsburgh Sleep Quality Index questionnaire for evaluating sleep quality. We employed SPSS ver. 21 for data analysis and considered 0.05 as a significant levelResults:Among all participants, 62 (38%) were female and 30.7% were illiterate. The mean age was 56.67 ± 12.90 years, and HbA1c was 9.03 ± 1.92 mg/dL. Among sleep metrics, mean waking time was 8.74 ± 1.74 hours, and average sleep time was 12.90 ± 4.90 hours. Overall, 58.2% of the participants had poor glycemic control and 44.8% were suffering from poor sleep quality. We found that patients with poor glycemic control exhibited significantly higher levels of sleep disturbances compared to those with good glycemic control (P< 0.001).Conclusion:Sleep quality is associated with glycemic control in patients with T2DM. Sleep disorders are common among diabetic patients. Thus, healthcare providers need to consider sleep quality improvement in their holistic approach to diabetes management.