bluuebunny/crossref_metadata_2025_split huggingface dataset:
Field Dependent Carrier Transport Mechanisms in Metal-Insulator–Metal Devices with Ba0.8Sr0.2TiO3/ ZrO2 Heterostructured Thin Films as the Dielectric
Authors: Sahoo Santosh K. , Bakhru H. , Kumar Sumit , Misra D. , Wolden Colin A. , Mohapatra Y. N. , Agrawal D. C. 
Published: July 2013

ABSTRACTBa0.8Sr0.2TiO3/ZrO2 heterostructured thin films with different individual layer ZrO2 thicknesses are deposited on Pt/Ti/SiO2/Si substrates by a sol-gel process. The current versus voltage (I-V) measurements of the above multilayered thin films in metal-insulator-metal (MIM) device structures are taken in the temperature range of 310 to 410K. The electrical conduction mechanisms contributing to the leakage current at different field regions have been studied in this work. Various models are used to know the different conduction mechanisms responsible for the leakage current in these devices. It is observed that Poole-Frenkel mechanism is the dominant conduction process in the high field region with deep electron trap energy levels (φt) whereas space charge limited current (SCLC) mechanism is contributing to the leakage current in the medium field region with shallow electron trap levels (Et). Also, it is seen that Ohmic conduction process is the dominant mechanism in the low field region having activation energy (Ea) for the electrons. The estimated trap level energy varies from 0.2 to 1.31 eV for deep level traps and from 0.08 to 0.18 eV for shallow level traps whereas the activation energy for electrons in ohmic conduction process varies from 0.05 to 0.17 eV with the increase of ZrO2 sub layer thickness. An energy band diagram is given to explain the dominance of the various leakage mechanisms in different field regions for these heterostructured thin films.
Thin Films Made from Colloidal Antimony Tin Oxide Nanoparticles for Transparent Conductive Applications
Authors: Halim Abigail , Gerhardt Rosario A. 
Published: July 2013

ABSTRACTCommercially available antimony tin oxide (ATO) nanoparticles were dispersed in water using tetramethylammonium hydroxide (TMAH) as a dispersing agent and deposited onto glass substrates by spin coating. Films of one to five layers were made. These thin films were characterized using impedance spectroscopy and ultraviolet-visible spectroscopy to obtain their sheet resistances and optical transmittance, respectively. The films displayed sheet resistances around 105-106 kΩ/☐ and optical transmittance in the near infrared to near ultraviolet range above 95%. Films were then made using a higher concentration ATO solution and found to achieve sheet resistances on the order of 102 kΩ/☐ but had decreased transmittance as low as 65% at some wavelengths. Impedance measurements, along with optical micrographs, were taken at different locations on the films. These experiments demonstrated that films of more than one layer showed greater uniformity. Additional sets of films were also produced with varying substrate preparation and dispersion deposition parameters. Aside from dispersion concentration, high humidity during film measurement was found to be the most crucial parameter for achieving low sheet resistances.
RLC electrical circuit of non-integer order
Authors: Gómez Francisco , Rosales Juan , Guía Manuel 
Published: July 2013

Abstract
In this work a fractional differential equation for the electrical RLC circuit is studied. The order of the derivative being considered is 0 < γ ≤ 1. To keep the dimensionality of the physical quantities R, L and C an auxiliary parameter γ is introduced. This parameter characterizes the existence of fractional components in the system. It is shown that there is a relation between and σ through the physical parameters RLC of the circuit. Due to this relation, the analytical solution is given in terms of the Mittag-Leffler function depending on the order of the fractional differential equation.
Recent progress in pancreatic cancer
Authors: Wolfgang Christopher L. , Herman Joseph M. , Laheru Daniel A. , Klein Alison P. , Erdek Michael A. , Fishman Elliot K. , Hruban Ralph H. 
Published: July 2013

Answer questions and earn CME/CNEPancreatic cancer is currently one of the deadliest of the solid malignancies. However, surgery to resect neoplasms of the pancreas is safer and less invasive than ever, novel drug combinations have been shown to improve survival, advances in radiation therapy have resulted in less toxicity, and enormous strides have been made in the understanding of the fundamental genetics of pancreatic cancer. These advances provide hope but they also increase the complexity of caring for patients. It is clear that multidisciplinary care that provides comprehensive and coordinated evaluation and treatment is the most effective way to manage patients with pancreatic cancer. CA Cancer J Clin 2013;63:318‐348. ©2013 American Cancer Society.
Early integration of palliative care services with standard oncology care for patients with advanced cancer
Authors: Greer Joseph A. , Jackson Vicki A. , Meier Diane E. , Temel Jennifer S. 
Published: July 2013

Answer questions and earn CME/CNEScientific advances in novel cancer therapeutics have led to remarkable changes in oncology practice and longer lives for patients diagnosed with incurable malignancies. However, the myriad options for treatment have established a culture of cancer care that has not been matched with a similar availability of efficacious supportive care interventions aimed at relieving debilitating symptoms due to progressive disease and treatment side effects. Accumulating data show that the introduction of palliative care services at the time of diagnosis of advanced cancer leads to meaningful improvement in the experiences of patients and family caregivers by emphasizing symptom management, quality of life, and treatment planning. In this review article, the rationale and evidence base for this model of early palliative care services integrated into standard oncology care are presented. In addition, the implications and limitations of the existing data to 1) elucidate the mechanisms by which early palliative care benefits patients and families; 2) guide the dissemination and application of this model in outpatient settings; and 3) inform health care policy regarding the delivery of high‐quality, cost‐effective, and comprehensive cancer care are discussed. CA Cancer J Clin 2013;63:349‐363. © 2013 American Cancer Society, Inc.
Clinical audit for the tibial tuberosity advancement procedure
Authors: Corr S. A. , Proot J. L. J. 
Published: July 2013

SummaryObjective To quantitatively assess the learning curve for the tibial tuberosity advancement (TTA) procedure performed by a single surgeon using the cumulative summation (CUSUM) technique and to determine if surgeon performance remained under control (i.e. within specified quality boundaries) after the learning curve had been climbed. Study design: Retrospective study.Animals Dogs (n = 122) with cranial cruciate ligament deficient stifles (n = 167).Methods Records of all dogs that had a TTA procedure performed by the same surgeon were reviewed. Cases were included if the following information was available: weight, breed, date of surgery, presence of partial or full cruciate rupture, meniscal pathology, occurrence and description of postoperative complications and treatment with a minimum of 12 months follow-up. Patients were excluded if they had a concurrent illness. Major complications were defined as those requiring revision surgery. The CUSUM technique was used to determine the time taken for the surgeon to reach a pre-defined level of competency and to monitor ongoing performance.Results Major complications occurred in 15 out of 167 procedures (9%) within 12 months of TTA surgery. The complication rate decreased as surgical experience was gained with the technique, however the learning curve continued until the 22nd procedure. Thereafter, despite the target complication rate being re-set at a lower level, the surgeon's performance remained acceptable, i.e. within the revised quality boundary.Clinical significance The CUSUM technique was used for clinical audit, to determine the learning curve for the TTA procedure for a single surgeon, and to monitor ongoing performance. An experienced general practitioner had a learning curve of 22 procedures and complication rates were within the published ranges.
The effects of a novel lateral extracapsular suture system on the kinematics of the cranial cruciate deficient canine stifle
Authors: Lanz O. I. , Aulakh K. S. , Butler J. R. , McLaughlin R. M. , Harper T. A. , Werre S. R. , D´Amico L. L. 
Published: July 2013

SummaryObjective To evaluate the relative position of the femur and tibia in cranial cruciate ligament- intact stifles, cranial cruciate ligamentdeficient stifles, and cruciate-deficient stifles following lateral extracapsular suture system (LESS) stabilization under load at specific joint angles.Study design In vitro biomechanical study.Methods Twenty pelvic limbs from 11 dogs were used to evaluate the relative position of the femur and tibia between three stifle conditions (cranial cruciate ligament-intact, cranial cruciate ligament-deficient, and LESSstabilized) at a load of 30% of body weight and stifle angles of 125°, 135°, and 145° using electromagnetic tracking sensors.Results Cranial cruciate ligament-deficient stifles had significantly greater (p <0.0001) cranial displacement and internal rotation of the tibia relative to the femur than cranial cruciate ligament-intact or LESS stifles at all stifle angles. Cranial displacement of the tibia relative to the femur for cranial cruciate ligament-intact and LESS stifles were not significantly different from one another at a stifle angle of 125°, but were significantly different at stifle angles of 135° (p = 0.0182) and 145° (p = 0.0012). There was no significant difference in internal rotation of the tibia relative to the femur between the cranial cruciate ligament-intact and LESS stifles at any of the stifle angles.Clinical significance The LESS procedure effectively decreased cranial tibial displacement and eliminated internal rotation of the tibia relative to the femur in the cranial cruciate ligament-deficient stifles at stifle angles of 125°, 135°, and 145° in vitro.
Antibiogram and characterization of resistance markers among Escherichia coli Isolates from urinary tract infections
Authors: Kumar Yashwant , Sood Shivani , Sharma Anshu , Mani Kavaratty Raju 
Published: July 2013

Introduction: Urinary tract infection is the most frequently diagnosed kidney and urologic disease, and Escherichia coli is by far its most common etiological agent. Uropathogenic E. coli are responsible for approximately 90% of urinary tract infections seen in individuals with ordinary anatomy therefore, it is essential to review the antibiogram of uropathogenic E. coli periodically to help clinicians decide on the appropriate therapy. Methodology: We evaluated E. coli isolated from urinary tract infections at the National Salmonella and Escherichia Centre for antibiogram, plasmid transferability and stability of resistance markers. Results: In total, 90.9% of the isolates were found to be sensitive to nitrofurantoin while the highest proportion of the isolates was found to be resistant to nalidixic acid. Minimum inhibitory concentrations of all antimicrobials for different isolates were well within the limits specified by the Clinical and Laboratory Standards Institute. Resistance against tetracycline was not transferred either by conjugation and transformation. Streptomycin resistance was found to be lost in the maximum number of tested isolates showing loss at the 10th, 15th and 20th passages. Conclusion: Changing trends in antibiotic resistance necessitates the periodic generation of antibiogram data to help health authorities revise treatment strategies for urinary tract infections caused by E. coli.
Pandemic Influenza A(H1N1) in Cote d'Ivoire: health-care providers’ knowledge of influenza and attitudes towards vaccination
Authors: Coulibaly Daouda , Nzussouo Ndahwouh T , Kadjo Hervé A , Traoré Youssouf , Ekra Daniel K , Chérif Djibril , Kouassi Paquin D , N’gattia Anderson K , Dagnan Simplice N 
Published: July 2013

Introduction: During the 2009 influenza A(H1N1) pandemic (pH1N1), different methods were promoted to reduce the spread of influenza, including respiratory etiquette and vaccination. To identify knowledge gaps about influenza and to plan the vaccination campaign against the pandemic in Côte d’Ivoire, a survey was conducted among health-care providers (HCPs) to assess their knowledge about influenza and their willingness to be vaccinated. Methodology: A cross-sectional survey was performed in the city of Abidjan on 16-18 February 2010, in the three university teaching hospitals, a randomly selected general hospital, and two randomly selected private clinics. In face-to-face interviews, 383 health-care professionals were asked questions about their knowledge of influenza, means of influenza prevention, and their willingness to be vaccinated. Data analysis, both univariate and multivariate, was performed using SPSS. Results: Willingness to be vaccinated against pH1N1 was 80% (n = 284), and 83% of the HCPs would recommend the vaccine to others. The respiratory mode of transmission of influenza was known by 85% (n = 295) of the participants and 50% (n = 174) believed that seasonal influenza virus and pH1N1 virus were different. In a multivariate model, the factors significantly associated with willingness to receive pH1N1vaccine were fear of pH1N1 disease (OR = 2.1; IC = 1.02-4.35), having only a high school education (OR = 8.28; IC = 2.04-33.60), and feeling at risk to contract pH1N1 (OR = 11.43; IC = 4.77-27.38). Conclusion: The willingness to be vaccinated against influenza A (H1N1) by health professionals is real.
Seasonality, clinical types and prognostic factors of Vibrio vulnificus infection
Authors: Tsao Chien-Han , Chen Chun-Chieh , Tsai Shih-Jei , Li Chi-Rong , Chao Wai-Nang , Chan Khee-Siang , Lin Ding-Bang , Sheu Kai-Lun , Chen Shiuan-Chih , Lee Meng-Chih , Bell William R. 
Published: July 2013

Introduction: Vibrio vulnificus infection, an uncommon but life-threatening illness, manifests as two main types, primary septicemia and primary wound infections. Little information regarding the seasonality of V. vulnificus infections in tropical areas and prognostic factors of primary V. vulnificus wound infections is available. Methodology: This retrospective study was conducted to include 159 V. vulnificus-infected admissions at our institution in southern Taiwan, 63 with primary septicemia (Group 1) and 96 with primary wound infections (Group 2), from 1999 to 2008, for analysis. Results: The case-fatality rate was 24%. Eighty-eight percent of these cases occurred during April to November. During December to March, patients in Group 2 were less likely to have acquired the infection compared with those in Group 1. Group 1 was more likely to have comorbidities and a higher case-fatality rate compared to Group 2. In multivariate analysis, hemorrhagic bullous skin lesions/necrotizing fasciitis (P=0.024), lesions involving two or more limbs (P=0.043), and shock on admission (P=0.015) were related to an increased mortality risk, while surgery < 24 hours after admission (P=0.001) was related to a decreased mortality risk in Group 1; however, hemorrhagic bullous skin lesions/necrotizing fasciitis (P=0.045) was the only prognostic factor in Group 2. Conclusion: The presence of hemorrhagic bullous lesion/necrotizing fasciitis is the main prognostic factor for primary septicemia or primary wound infections caused by V. vulnificus. Persons with an underlying immunocompromised status should avoid consuming raw/undercooked seafood or exposing wounds to seawater and should wear clothing during handling of seafood/fishing, especially in warmer months.
Littérature et communauté : vitalité et reconnaissance du Far Ouest francophone
Authors: Sing Pamela V. 
Published: July 2013

Pendant presque un siècle, la « littérature franco-albertaine » a signifié les ouvrages de principalement un écrivain reconnu. Jusqu’aux années 1950, ce fut l’écrivain d’origine française, George Bugnet, qui s’est établi en Alberta peu de temps après la création de la province. De 1960 jusqu’à la fin du siècle, ce fut Marguerite-A. Primeau, qui, née à Saint-Paul-des-Métis dans le nord de l’Alberta, s’est établie à Vancouver en 1954. Or, depuis l’an 2000, la francophonie albertaine connaît une croissance démographique, institutionnelle et culturelle qui permet de parler de sa vitalité. Au seul plan littéraire, le nombre de ses écrivains, définis dans cet article comme les francophones qui sont nés en Alberta ou bien qui, originaires d’une autre francophonie, vivent et écrivent ou ont vécu et ont écrit en Alberta, a augmenté. Ils sont encore peu nombreux relativement aux milieux franco-manitobaine, franco-ontarienne ou acadienne, mais dans l’unique cadre albertain, le « Far Ouest » du titre, « cela bouge ». On pourrait dire que la communauté franco-albertaine se trouve actuellement non tant préoccupée par sa survivance, que soucieuse de son épanouissement. Du coup, elle cherche la reconnaissance. Auprès de qui? Par quels moyens? Cet article tente d’apporter quelques éléments de réponse à ces questions tout en réclamant pour la production littéraire un rôle particulièrement important.
Assembly of Synapses: Biomimetic Assays to Control Neurexin/Neuroligin Interactions at the Neuronal Surface
Authors: Mondin Magali , Tessier Béatrice , Thoumine Olivier 
Published: July 2013

AbstractThe role of adhesion molecules in the assembly of synapses in the nervous system is an important issue. To characterize the role of neurexin/neuroligin adhesion complexes in synapse differentiation, various imaging assays can be performed in primary hippocampal cultures. First, to temporally control contact formation, biomimetic assays can be performed using microspheres coated with purified neurexin or with antibody clusters that aggregate neurexin. These models are combined with live fluorescence imaging to study the dynamics of accumulation of post‐synaptic components, including scaffolding molecules and glutamate receptors. To demonstrate that AMPA receptors can be recruited to nascent neurexin/neuroligin contacts through lateral diffusion, the mobility of AMPA receptors in the neuronal membrane is monitored by tracking individual quantum dots (QDs) conjugated to antibodies against AMPA receptors. Experiments monitoring the attachment and detachment of Nrx‐coated QDs to measure the rates of neurexin/neuroligin interaction can also be performed. Each of these assays is detailed in this unit. Curr. Protoc. Neurosci. 64:2.19.1‐2.19.30. © 2013 by John Wiley & Sons, Inc.
Impact of temperature on Na2Sr(PO4)F:Eu3+ phosphor
Authors: Shinde KN , Pawade VB , Dhoble SJ , Hakeem A. 
Published: July 2013

ABSTRACTIn this article, we report the synthesis of Na2Sr1‐x(PO4)F:Eux phosphor via a combustion method. The influence of different annealing temperatures on the photoluminescence properties was investigated. The phosphor was excited at both 254 and 393 nm. Na2Sr1‐x(PO4)F:Eux3+ phosphors emit strong orange and red color at 593 and 612 nm, respectively, under both excitation wavelengths. Na2Sr1‐x(PO4)F:Eux3+ phosphors annealed at 1050°C showed stronger emission intensity compared with 600, 900 and 1200°C. Moreover, Na2Sr1‐x(PO4)F:Eux3+ phosphor was found to be more intense when compared with commercial Y2O3:Eu3+ phosphor. Copyright © 2013 John Wiley & Sons, Ltd.
Screening of phage‐displayed human liver cDNA library against doxorubicin with drug‐immobilized monolithic polyacrylamide cryogel
Authors: Yu Xiaoming , Zhao Peng , Zhang Lihua , Zhang Yukui 
Published: July 2013

ABSTRACTMonolithic polyacrylamide cryogel was prepared and utilized as a new matrix for drug immobilization to screen against phage‐displayed human liver cDNA library. The macropores and hydrophilic nature of the cryogel made it possible for phage particles to pass unhindered. Doxorubicin, an anticancer drug, was covalently bonded to the monolithic cryogel by the glutaraldehyde method, and after five rounds of affinity selection performed in an SPE cartridge, phage clones that displayed Homo sapiens methyl CpG binding protein 2 (MeCP2) were selectively enriched. The interaction between doxorubicin and MeCP2 displayed phages was further validated by studying the retention of doxorubicin on MeCP2 phage‐coupled cryogel. These results demonstrate that drug‐coupled polyacrylamide cryogel might be a promising kind of matrix for screening target proteins against phage‐displayed library. Copyright © 2013 John Wiley & Sons, Ltd.
Determination of pseudo‐ginsenoside GQ in human plasma by high performance liquid chromatography–tandem mass spectrometry
Authors: Huo Jiping , Wang Hongyun , Hu Pei , Li Pingya , Liu Jinping , Jiang Ji 
Published: July 2013

ABSTRACTA specific, sensitive and rapid method based on high performance liquid chromatography coupled to tandem mass spectrometry (HPLC‐MS/MS) was developed for the determination of pseudo‐ginsenoside GQ in human plasma. Liquid–liquid extraction was used to isolate the analyte from biological matrix followed by injection of the extracts onto a C8 column with isocratic elution. Detection was carried out on a triple quadrupole tandem mass spectrometer (API‐4000 system) in multiple reaction monitoring mode using negative electrospray ionization. The mobile phase consisted of methanol–10 mm ammonium acetate (90:10, v/v) and the flow rate was 0.3 mL/min. The method was validated over the concentration range of 5.0–5000.0 ng/mL for plasma. Inter‐ and intra‐day precisions (relative standard deviation) were all within 15% and the accuracy (relative error) was ≤9.4%. The lower limit of quantitation was 5.0 ng/mL. The pseudo‐ginsenoside GQ was stable after 8 h at room temperature, 24 h at autosampler and three freeze–thaw cycles (from −30 to 25 °C). The method was successfully applied to the pharmacokinetic study of pseudo‐ginsenoside GQ in healthy Chinese volunteers. Copyright © 2013 John Wiley & Sons, Ltd.
On multiuser perspectives in passive stereographic virtual environments
Authors: Tripicchio Paolo , Loconsole Claudio , Piarulli Andrea , Ruffaldi Emanuele , Tecchia Franco , Bergamasco Massimo 
Published: July 2013

ABSTRACTThe use of stereographic systems is spreading out in modern society, from the revolution of cinematography to its adoption in high‐tech products such as portable gaming devices or photo cameras. However, the fruition of immersive stereographic systems by more than one person at a time is still a research issue. In more detail, the class of passive stereo systems presents technological limitations of displaying correct multiuser perspectives. In fact, the stereo image projected onto the screen is usually rendered according to a unique point of view (PoV). Nevertheless, in multiuser systems, the selection of an appropriate PoV can minimize both optical discomfort and perspective distortion. This paper aims to evaluate which among existing PoV calculation methods provides the best performances in terms of projection realism, optical comfort and overall system usability in multiuser passive stereo systems. The performances have been evaluated in three different “distance” scenarios to take into account also the effects of binocular disparity in the PoV calculation. To accomplish this objective, we administered a questionnaire to nine couple subjects, evaluating each of the investigated PoV calculation methods for each of the three distance scenarios. Copyright © 2013 John Wiley & Sons, Ltd.