bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gonioscopy-assisted Transluminal Trabeculotomy (GATT): Thermal Suture Modification With a Dye-stained Rounded Tip
Authors: Grover Davinder S. , Fellman Ronald L. 
Published: September 2015

Purpose:
To describe a novel technique for thermally marking the tip of a suture, in preparation for a gonioscopy-assisted transluminal trabeculotomy.

Patient:
One patient was used as an example for this technique.

Methods:
Technique report.

Results and Conclusions:
The authors introduce a modification of a novel surgical procedure (GATT) in which a suture is marked and thermally blunted allowing a proper visualization while performing an ab interno, minimally invasive, circumferential 360-degree suture trabeculotomy. The authors have previously reported on the GATT surgery with the use of an illuminated microcatheter, which allowed for visualization of the tip of the catheter as it circumnavigated Schlemm canal. This modification allows for similar visualization of the tip of the suture, however, is much more cost-effective while still maintaining similar safety.
FINEMAP: Efficient variable selection using summary data from genome-wide association studies
Authors: Benner Christian , Spencer Chris C.A. , Ripatti Samuli , Pirinen Matti 
Published: September 2015

AbstractMotivationThe goal of fine-mapping in genomic regions associated with complex diseases and traits is to identify causal variants that point to molecular mechanisms behind the associations. Recent fine-mapping methods using summary data from genome-wide association studies rely on exhaustive search through all possible causal configurations, which is computationally expensive.ResultsWe introduce FINEMAP, a software package to efficiently explore a set of the most important causal configurations of the region via a shotgun stochastic search algorithm. We show that FINEMAP produces accurate results in a fraction of processing time of existing approaches and is therefore a promising tool for analyzing growing amounts of data produced in genome-wide association studies.AvailabilityFINEMAP v1.0 is freely available for Mac OS X and Linux athttp://www.christianbenner.com.Contact:christian.benner@helsinki.fi,matti.pirinen@helsinki.fi
Applying the maturity model concept to the servitization process of consumer durables companies in Brazil
Authors: Alvarez Rodrigo L. P. , Martins Marcelo Ramos , Silva Marcia Terra 
Published: September 2015

Purpose
– The purpose of this paper is to contribute to the understanding of the servitization process of typical manufacturing companies that already provide after-sales services, by identifying the phases and organizational elements that enable the delivery of more services.

Design/methodology/approach
– A servitization maturity model for consumer durables companies is proposed. Servitization is an evolutionary process based on customer profiling, company profiling, the nature of the service, maturity of the process and process characteristics. The capacity of maintaining organizational relationships among players in the value chain describes the organizational maturity needed to advance towards the next phase. The research has been conducted as an exploratory study, in which four different case studies of consumer durables companies were performed to validate the proposed maturity model and detail each phase and the critical resources needed to become servitized.

Findings
– Four category levels of organizational relationships were identified: first, company and customers; second, company and production network; third, company and market, in addition to; fourth, the internal relations of the company.

Practical implications
– The means to evaluate companies that undergo servitization are also presented to provide a better understanding of their placement in the process and guide managers through the next necessary steps of action.

Originality/value
– The development and application of this model allowed exploring the levels of servitization as an evolutionary process based on the relationships among players in the value chain by gathering, structuring, organizing several critical requirements and highlighting important attributes that must be examined by companies during the servitization process.
Leadership, governance, and organization in higher education: select books for administrators
Authors: Frey Susan 
Published: September 2015

Purpose
– The purpose of this bibliography is to provide academic administrators, and those studying higher education administration, a targeted collection of recommended resources that inform the practice of academic management.

Design/methodology/approach
– Reading lists from two advanced educational programs were consulted: Indiana State University’s faculty training program, Leadership-ISU, sponsored by the Office of the President, and the Indiana State University doctoral program in higher education administration, taught by the Bayh College of Education. Criteria for selection were based on canonicity, comprehensiveness and the inclusion of useful bibliographies and practical appendices.

Findings
– Broad scholarship on management, traditionally focused on for-profit institutions, can sometimes be applied to academia. But management research specific to that of the higher education environment more fully addresses the corresponding information needs of the academic administrator.

Research limitations/implications
– A limitation of this bibliography is its scope. Due to the rich environment of research on academic management, any abridgement of this literature will result in the omission of many worthy titles. Just seven English language, print-based publications are selected as representative of the pool. Although many of the concepts found in these resources can be generalized to all of academia, authors’ perspectives mainly concern higher education environments in North America.

Originality/value
– The literature on academic management is rich and varied. This bibliography pulls together representative and canonical works providing a focused, one-shelf collection of critical resources for busy practitioners and novice researchers.
Occupational therapy influence on a carer peer support model in a clinical mental health service
Authors: Bourke Cate , Sanders Bronwyn , Allchin Becca , Lentin Primrose , Lang Shannon 
Published: September 2015

Background/aimCurrent policy frameworks call for the participation of consumers and carers in all levels of mental health service delivery in Australia. Such inclusion leads to better outcomes for all, however, it is recognised that carers have needs and occupations beyond their carer role. The aim of this article is to describe an innovative carer peer support program developed by a group of occupational therapists. The article describes the rationale, phases of development and the role that occupational therapists played in developing and sustaining the model. This is followed by an exploration of the occupational therapy attitudes, knowledge and skills that contributed to the conceptualisation and implementation of the model.MethodFive occupational therapists engaged in a review process involving documentation, literature review, evaluation, reflection and discussion. Four of the occupational therapists had either coordinated or managed the service described. The fifth author facilitated the process.ResultsReview of the model indicates it equips carers to perform their caring occupation and helps carers recognise the need for occupations beyond caring, for their health and wellbeing. Employing carers as paid workers values their ‘real life’ experience in their caring occupation. Findings also illustrate that the attitudes, knowledge, skills and competency standards of occupational therapists are well suited in enabling this emerging area of service delivery.ConclusionAlthough this model has been developed in a clinical mental health setting, the key principles could be applied with carers or consumers across a variety of settings in which occupational therapists are employed.
Diversity patterns of Rhizobiaceae communities inhabiting soils, root surfaces and nodules reveal a strong selection of rhizobial partners by legumes
Authors: Miranda‐Sánchez Fabiola , Rivera Javier , Vinuesa Pablo 
Published: September 2015

SummaryCurrent knowledge about rhizobial diversity patterns in non‐nodule habitats is scarce, limiting our understanding of basic aspects of rhizobial ecology like competitiveness for nodule occupancy and host effects on community structure. We used a combination of cultivation‐dependent and independent approaches to analyse alpha and beta diversity patterns of Rhizobiaceae communities from a conserved seasonally dry tropical forest site in central Mexico and two nearby agricultural fields. Lineage‐specific recA amplicon libraries were generated from soil DNA and their sequences compared with those from root surface and nodule isolates recovered in trapping experiments from two native Acacia species and two Phaseolus vulgaris cultivars. Rarefaction analyses revealed that Rhizobiaceae diversity in soils is larger than on root surfaces, and smallest in nodules. A ‘rare biosphere'‐like distribution of species was found in the three habitats. Multivariate statistical analyses demonstrated that the plant genus exerted a stronger influence than the land‐usage regime on the diversity of rhizobia associated with hosts. Rhizobium etli was the dominant Rhizobiaceae found in the soil libraries. It dominated nodulation of Acacia spp. and predominately harboured symbiovar mimosae‐like nodC genes. A novel Rhizobium lineage (Rsp1) dominated bean nodulation. Specialist and generalist genotypes for host nodulation were detected in both species.
The Elizabethan Puritan Movement (1967)
Authors: Lake Peter 
Published: September 2015

AbstractThis essay seeks to set Patrick Collinson's book The Elizabethan Puritan Movement within the historiographical context in which it was written, within the context provided by his own subsequent oeuvre and in that provided by the succeeding historiography. It is intended as both an appreciation and a critique, but one offered with the greatest respect to a great scholar. It suggests that from the outset Collinson's work was contained within a triad linking religion, politics and, for want of a better word, ‘culture’ and that his work was at its best when politics retained its place as a central organizing principle and his other claims and concerns remained firmly attached, either explicitly or implicitly, to some form of, local, national or even interpersonal, political narrative.
‘A mere historian’: Patrick Collinson and the Study of Literature
Authors: Kewes Paulina 
Published: September 2015

AbstractPatrick Collinson experienced a ‘cultural’ or more specifically a ‘literary’ turn in mid‐career (the early 1980s) which had a profound effect on how he ‘did’ history. He rarely wrote about overtly ‘literary’ texts, but he helped to shape the area in which historians and literary scholars could have fruitful dialogue (sixteenth‐century histories and sermons, for example). This essay explores three aspects of this story. First, it examines when, where, how and with whom he came to experience a new and transformative relationship with English literature and its scholars. Second, it scrutinizes the precise forms of that relationship. Third, it considers which of his publications have most influenced English studies and why others, arguably no less important, have been relatively neglected. It finds him at once passionate and strangely diffident, deeply hostile to the New Historicism, for example, but never willing to define his own position against those of whom he was so wary. Despite this, the essay seeks to demonstrate how deeply influential his empirical studies have been in a multi‐disciplinary context.
Do Audit Clients Successfully Engage in Opinion Shopping? Partner‐Level Evidence
Authors: CHEN FENG , PENG SONGLAN , XUE SHUANG , YANG ZHIFENG , YE FEITENG 
Published: September 2015

ABSTRACTThis study investigates whether companies engage in audit opinion shopping activities by exerting influence over an audit firm's decision to switch the engagement partner (“partner‐level opinion shopping”) in the Chinese setting, where the identities of engagement partners are publicly disclosed. Adopting the empirical framework developed by Lennox [2000], we show evidence that companies successfully engage in partner‐level opinion shopping. Further, partner‐level opinion shopping is more likely to be successful if a company is economically important to an audit firm, and it is less likely to be successful if the audit firm is formed as a partnership rather than a corporation. We also find that companies successfully engaging in partner‐level opinion shopping exhibit significantly lower earnings quality. Finally, we directly compare audit records between incoming and outgoing partners and find that, for companies that successfully improve audit opinions after partner switching, incoming partners have a significantly higher propensity to issue clean opinions than their outgoing counterparts.
Conspiracies, Conspiracy Theories and Democracy
Authors: Moore Alfred 
Published: September 2015

Conspiracy theories are attracting increasing attention from political scientists, much of it negative. Three recent books, from the disciplines of political science, cultural history and social theory, provide a valuable critical corrective. Uscinski and Parent argue that conspiracy theories are connected to partisan distrust and are largely stable across the twentieth century. Michael Butter uses detailed historical cases from the Puritan witch trials to the Red Scare of the 1950s to show the central and influential role that conspiratorial beliefs have played in American history. Luc Boltanski focuses on conspiracy narratives in early detective and spy novels, but situates them in a broader account of the relation between the state, the social and political sciences, and popular representations of political power. Taken together, these books place the problem of conspiracy theory firmly in the context of democratic politics, opening important empirical and conceptual questions about partisanship, populism, publicity and secrecy. Boltanski, L. (2014) Mysteries and Conspiracies: Detective Stories, Spy Novels and the Making of Modern Societies. Translated by Catherine Porter. Cambridge: Polity Press. Butter, M. (2014) Plots, Designs and Schemes: American Conspiracy Theories from the Puritans to the Present. Berlin: Walter de Gruyter. Uscinski, J. E. and Parent, J. M. (2014) American Conspiracy Theories. Oxford: Oxford University Press.
Bayesian Framework for Parametric Bivariate Accelerated Lifetime Modeling and Its Application to Hospital Acquired Infections
Authors: Bilgili D. , Ryu D. , Ergönül Ö. , Ebrahimi N. 
Published: September 2015

Summary
Infectious diseases that can be spread directly or indirectly from one person to another are caused by pathogenic microorganisms such as bacteria, viruses, parasites, or fungi. Infectious diseases remain one of the greatest threats to human health and the analysis of infectious disease data is among the most important application of statistics. In this article, we develop Bayesian methodology using parametric bivariate accelerated lifetime model to study dependency between the colonization and infection times for Acinetobacter baumannii bacteria which is leading cause of infection among the hospital infection agents. We also study their associations with covariates such as age, gender, apache score, antibiotics use 3 months before admission and invasive mechanical ventilation use. To account for singularity, we use Singular Bivariate Extreme Value distribution to model residuals in Bivariate Accelerated lifetime model under the fully Bayesian framework. We analyze a censored data related to the colonization and infection collected in five major hospitals in Turkey using our methodology. The data analysis done in this article is for illustration of our proposed method and can be applied to any situation that our model can be used.
Identification of N‐arachidonoyl dopamine as a highly biased ligand at cannabinoid CB1 receptors
Authors: Redmond William J. , Cawston Erin E. , Grimsey Natasha L. , Stuart Jordyn , Edington Amelia R. , Glass Michelle , Connor Mark 
Published: September 2015

Background and PurposeN‐arachidonyl dopamine (NADA) has been identified as a putative endocannabinoid, but there is little information about which signalling pathways it activates. The purpose of this study was to identify the signalling pathways activated by NADA in vitro.Experimental ApproachHuman or rat cannabinoid CB1 receptors were expressed in AtT20, CHO or HEK 293 cells. NADA displacement of radiolabelled cannabinoids, and CB1 receptor mediated activation of K channels or ERK phosphorylation, release of intracellular calcium ([Ca]i) and modulation of adenylyl cyclase were measured in addition to NADA effects on CB1 receptor trafficking.Key ResultsAt concentrations up to 30 μM, NADA failed to activate any signalling pathways via CB1 receptors, with the exception of mobilization of [Ca]i. The elevations of [Ca]i were insensitive to pertussis toxin, and reduced or abolished by blockers of Gq/11‐dependent processes including U73122, thapsigargin and a peptide antagonist of Gq/11 activation. Prolonged NADA incubation produced modest loss of cell surface CB1 receptors. The prototypical cannabinoid agonist CP55940 signalled as expected in all assays.Conclusions and ImplicationsNADA is an ineffective agonist at most canonical cannabinoid receptor signalling pathways, but did promote mobilization of [Ca]i via Gq‐dependent processes and some CB1 receptor trafficking. This signalling profile is distinct from that of any known cannabinoid, and suggests that NADA may have a unique spectrum of effects in vivo. Our results also indicate that it may be possible to identify highly biased CB1 receptor ligands displaying a subset of the pharmacological or therapeutic effects usually attributed to CB1 ligands.
Cost‐effective conservation of an endangered frog under uncertainty
Authors: Rose Lucy E. , Heard Geoffrey W. , Chee Yung En , Wintle Brendan A. 
Published: September 2015

AbstractHow should managers choose among conservation options when resources are scarce and there is uncertainty regarding the effectiveness of actions? Well‐developed tools exist for prioritizing areas for one‐time and binary actions (e.g., protect vs. not protect), but methods for prioritizing incremental or ongoing actions (such as habitat creation and maintenance) remain uncommon. We devised an approach that combines metapopulation viability and cost‐effectiveness analyses to select among alternative conservation actions while accounting for uncertainty. In our study, cost‐effectiveness is the ratio between the benefit of an action and its economic cost, where benefit is the change in metapopulation viability. We applied the approach to the case of the endangered growling grass frog (Litoria raniformis), which is threatened by urban development. We extended a Bayesian model to predict metapopulation viability under 9 urbanization and management scenarios and incorporated the full probability distribution of possible outcomes for each scenario into the cost‐effectiveness analysis. This allowed us to discern between cost‐effective alternatives that were robust to uncertainty and those with a relatively high risk of failure. We found a relatively high risk of extinction following urbanization if the only action was reservation of core habitat; habitat creation actions performed better than enhancement actions; and cost‐effectiveness ranking changed depending on the consideration of uncertainty. Our results suggest that creation and maintenance of wetlands dedicated to L. raniformis is the only cost‐effective action likely to result in a sufficiently low risk of extinction. To our knowledge we are the first study to use Bayesian metapopulation viability analysis to explicitly incorporate parametric and demographic uncertainty into a cost‐effective evaluation of conservation actions. The approach offers guidance to decision makers aiming to achieve cost‐effective conservation under uncertainty.
Functional brain organization for number processing in pre‐verbal infants
Authors: Edwards Laura A. , Wagner Jennifer B. , Simon Charline E. , Hyde Daniel C. 
Published: September 2015

AbstractHumans are born with the ability to mentally represent the approximate numerosity of a set of objects, but little is known about the brain systems that sub‐serve this ability early in life and their relation to the brain systems underlying symbolic number and mathematics later in development. Here we investigate processing of numerical magnitudes before the acquisition of a symbolic numerical system or even spoken language, by measuring the brain response to numerosity changes in pre‐verbal infants using functional near‐infrared spectroscopy (fNIRS). To do this, we presented infants with two types of numerical stimulus blocks: number change blocks that presented dot arrays alternating in numerosity and no change blocks that presented dot arrays all with the same number. Images were carefully constructed to rule out the possibility that responses to number changes could be due to non‐numerical stimulus properties that tend to co‐vary with number. Interleaved with the two types of numerical blocks were audio‐visual animations designed to increase attention. We observed that number change blocks evoked an increase in oxygenated hemoglobin over a focal right parietal region that was greater than that observed during no change blocks and during audio‐visual attention blocks. The location of this effect was consistent with intra‐parietal activity seen in older children and adults for both symbolic and non‐symbolic numerical tasks. A distinct set of bilateral occipital and middle parietal channels responded more to the attention‐grabbing animations than to either of the types of numerical stimuli, further dissociating the specific right parietal response to number from a more general bilateral visual or attentional response. These results provide the strongest evidence to date that the right parietal cortex is specialized for numerical processing in infancy, as the response to number is dissociated from visual change processing and general attentional processing.