bluuebunny/crossref_metadata_2025_split huggingface dataset:
IMPLEMENTASI PERAN GURU DALAM STRATEGI PEMBELAJARAN TEMATIK BERBASIS MULTIPLE INTELLIGENCES KELAS IV SD PLUS AL KAUTSAR MALANG
Authors: Akbarani Masyitha Dwi 
Published: August 2024

ABSTRACT
Learning strategies as a way for teachers to achieve learning objectives. Basically, every child born into this world is an intelligent child with various potentials and uniqueness (multiple intelligences). This research uses a qualitative type of research. Datacollection techniques by means of observasi, interviews and documentation, while checking the validity of data using source triangulation techniques, data triangulation and time triangulation. In practice, each child has more than one type of intelligence. There are children who are good at science studies, but have a hobby of singing. It's just that at certain times the type of intelligence is more inclined or dominant to one type of intelligence among the nine types of multiple intelligence types. Factors that influence the implementation of the teacher's role are internal factors such as physical, interest, talent, experience, self-confidence and health. External factors are parents' attention to their children, learning with learning styles that suit students, and teachers' ability to combine appropriate strategies and learning methods.

ABSTRAK
Strategi pembelajaran sebagai cara guru dalam mencapai tujuan pembelajaran. Pada dasarnya, setiap anak yang terlahir ke dunia ini merupakan anak-anak cerdas dengan berbagai potensi dan keunikan (multiple intelligences). Penelitian ini menggunakan jenis penelitian kualitatif. Teknik pengumpulan data dengan cara observasi, wawancara dan dokumentaasi, sedangkan pengecekan keabsahan data menggunakan teknik triangulasi sumber, triangulasi data dan triangulasi waktu. Dalam penerapannya, setiap anak memiliki lebih dari satu tipe kecerdasan. Ada anak yang pandai dalam pelajaran sains, tetapi memiliki hobi bernyanyi. Hanya saja pada waktu tertentu tipe kecerdasan tersebut lebih condong atau dominan pada satu tipe kecerdasan diantara Sembilan jenis tipe kecerdasan multiple. Faktor yang memengaruhi implementasi peran guru adalah faktor dari dalam seperti fisik, minat, bakat, pengalaman, kepercayaan diri dan Kesehatan. Faktor dari luar yaitu perhatian orang tua terhadap anaknya, pembelajaran dengan gaya belajar yang sesuai dengan siswa, dan kemampuan guru dalam memadukan stategi dan metode belajar yang sesuai
ANALISIS KESIAPAN GURU DALAM IMPLEMENTASI KURIKULUM MERDEKA BELAJAR PADA PENDIDIKAN DASAR
Authors: Aida Ana Nur 
Published: August 2024

ABSTRACT
The development of science and technology demands adaptation from various elements of education to encourage curriculum renewal. The Merdeka Curriculum is a renewed curriculum based on technological advances and reduced learning loss due to the Covid-19 pandemic. Welcoming the new curriculum, teacher readiness is needed so that learning can be delivered optimally. This study aims to determine the readiness of teachers in implementing the Merdeka Curriculum, especially at the basic education level. This article uses a qualitative method with a type of literature study. Data collection techniques by collecting various sources both from books, journals, and others related to the concept of discussion.

ABSTRAK
Perkembangan ilmu pengetahuan dan teknologi menuntut adaptasi dari berbagai elemen pendidikan hingga mendorong pembaharuan kurikulum. Kurikulum Merdeka merupakan suatu kurikulum hasil pembaharuan yang dilatarbelakangi oleh kemajuan teknologi dan mengurangi learning loss akibat pandemic Covid-19. Menyongsong kurikulum baru, kesiapan guru dibutuhkan agar pembelajaran dapat tersampaikan secara optimal. Penelitian ini bertujuan untuk mengetahui kesiapan guru dalam mengimplementasikan Kurikulum Merdeka, khususnya pada tingkat pendidikan dasar. Artikel ini menggunakan metode kualitatif dengan jenis studi literatur. Teknik pengumpulan data dengan mengumpulkan berbagai sumber baik dari buku, jurnal, dan lainnya yang berkaitan dengan konsep bahasan.
DINAMIKA NU DAN MODERNISME KEAGAMAAN
Authors: H Hamidah 
Published: August 2024

Sejarah masuk dan berkembangnya Islam di Indonesia tidak dapat dipisahkan dari keterlibatan kegiatan perdagangan yang berkembang sejak abad ke XI. Adanya kontak dagang tersebut menyebabkan tumbuhnya pemukiman masyarakat muslim di wilayah pesisir kepulauan Nusantara, sehingga lambat laun Islam telah menjadi bagian yang menguasai batin masyarakat Indonesia.
Keberadaan Islam di Indonesia tidak terlepas dari kultur masyarakat setempat. Pergumulan Islam dengan kultur yang telah mendarah daging menuntut adanya adaptasi yang kontinu tanpa harus kehilangan ide aslinya. Islam, ketika berhadapan dengan realitas sejarah, akan memunculkan realitas baru yang tidak hanya diakibatkan pergumulan internalnya dalam merespon masalah yang muncul tetapi juga keterlibatannya dalam proses sejarah yang bertindak sebagai subyek yang ikut membentuk keadaan zaman.
Gut microbiota prevents small intestinal tumor formation due to bile acids in gnotobiotic mice
Authors: Wortmann Esther , Wylensek David , Basic Marijana , Hermeling Sven , Bleich André , Haller Dirk , Tolba René , Liebisch Gerhard , Janssen Klaus-Peter , Clavel Thomas 
Published: August 2024

Aim: The gut microbiota is implicated in the development of intestinal tumors. Furthermore, Western diet is a risk factor for colorectal cancer and induces alterations in both the microbiota and bile acid metabolism. Therefore, we aimed to investigate the causal role of Western diet-induced changes in the microbiota and secondary bile acid production, which were linked to disease exacerbation in APC 1311/+ pigs.
Methods: We performed fecal microbiota transfer experiments by inoculating germfree Apc 1368N/+ mice with stool from genetically engineered APC 1311/+ pigs. A control group of Apc 1368N/+ mice stayed germfree. All mice were fed either a control diet, or the same diet supplemented with the primary bile acid cholic acid (CA) to stimulate secondary bile acid production.
Results: Unexpectedly, the germfree mice fed CA had a high number of lesions in the upper small intestine, which was reduced by the colonization with microbes. The same mice (germfree, CA diet) were characterized by a remarkable lengthening of the small intestine (approximately +10 cm on average). Colonic lesions were rare and only observed in the mice that received stool from control pigs and fed the CA diet. Diversity and composition analyses showed that the microbiota transfer was incomplete. Nevertheless, mice receiving the Western diet-associated microbiota clustered separately from control animals. The effects of the CA diet on the microbiota were less pronounced and were observed primarily in mice that received stool from control pigs. Bile acid analysis in the recipient mice revealed associations between the phenotype and specific bile acid species in bile and cecum.
Conclusion: This descriptive study highlights the importance of diet-microbiota-bile acid interactions in intestinal morphogenesis and tumorigenesis.
The inner elbow skin microbiome contains Lactobacillus among its core taxa and varies with age, season and lifestyle
Authors: Delanghe Lize , De Boeck Ilke , Van Malderen Joke , Gehrmann Thies , Allonsius Camille Nina , Bron Peter A. , Claes Ingmar , Hagendorens Margo , Leysen Julie , Wittouck Stijn , Lebeer Sarah 
Published: August 2024

Background: The human skin microbiome plays an essential role in protecting against pathogens and other external substances. This open ecosystem is also influenced by personal and environmental factors, but the precise impact of these factors, such as lifestyle and season, is understudied. We focused here on the inner elbow, a skin site prone to inflammatory conditions like atopic dermatitis and psoriasis.
Methods: We collected skin swabs from the inner elbow of 52 children and adults, with no signs of skin disorders, in the winter and summer seasons. Samples were analyzed using metagenomic shallow shotgun sequencing. In addition, metadata were collected using questionnaires on health, lifestyle, and environmental factors.
Results: The core inner elbow community, taxa with a prevalence of 95% or higher, consisted of several well-known skin taxa, such as Staphylococcus hominis , Staphylococcus capitis , Staphylococcus epidermidis , and Cutibacterium acnes . In addition, Streptococcus and Lactobacillus species were also found to be highly prevalent members of the skin microbiota, especially in the age group up to 3 years old. Of all investigated factors, age appeared to be the major driver defining the skin microbiome composition and longitudinal stability over the seasons. Differential abundance analysis using three statistical tests also pointed out that specific skin species were significantly associated with sampling season, age, hygiene practices, vitamin D supplements, probiotics, and the number of household members.
Conclusion: This study identifies novel factors influencing the inner elbow skin microbiome composition and paves the way for future comparative and intervention studies in skin disorders such as atopic dermatitis.
Digital Activism, Bahasa, dan Politik Representasi Film
Authors: Rianto Puji 
Published: August 2024

Artikel-artikel yang terbit di Jurnal Komunikasi Volume 18, Nomor 2, 2024 masih melanjutkan kecenderungan kajian-kajian sebelumnya yang terbit di Jurnal Komunikasi edisi sebelumnya. Kajian tersebut memberikan perhatian pada kehadiran media digital atau secara khusus media sosial. Penetrasi internet dan media sosial yang semakin luas di masyarakat (APJII, 2022) tampaknya menarik perhatian lebih banyak peneliti di Indonesia untuk mengkaji fenomena tersebut. Menariknya, kajian-kajian itu lebih memberikan perhatian pada kontribusi penting kehadiran media digital bagi pemberdayaan dan juga perlawanan masyarakat atau yang sering dikenal luas sebagai netizen dalam mendorong perubahan. Kajian ini bukanlah sama sekali baru karena banyak peneliti sebelumnya telah memberikan perhatian pada media digital dalam mendorong perubahan (Lim, 2017; Rianto, 2023; Suwana, 2020; Valera-Ordaz & López-García, 2019), tetapi luasnya bidang ini telah membuka area-area penelitian yang baru. Digital activsm tidak hanya masuk dalam ranah politik (Saud & Margono, 2021; Suwana, 2020), tetapi juga mencakup gerakan-gerakan yang lebih luas, termasuk meluasnya budaya pembatalan (Driessen, 2023; Rutledge, 2021; Verga et al., 2021) atau gerakan berorientasi pada pola hidup berkelanjutan (Cahyaningtyas et al., 2021). Hasil-hasilnya pun tergantung pada banyak faktor (Lim, 2017; Rianto et al., 2024). Pada edisi ini, hanya satu artikel yang tidak membahas kajian media digital, yakni kajian yang dilakukan oleh Ismail & Wijaksono. Fokusnya pada voluntarisme masyarakat dalam menanggulangi pandemi Covid-19.
Implementation of Al-Islam and Kemuhammadiyahan (AIK) Learning Development through Al-Islam Intensive Lecture Training (KIAI)
Authors: Hidayat Yayat 
Published: August 2024

This research is expected to be able to encourage the development of al-Islam and Kemuhammadiyahan learning that is being the characteristic in Muhammadiyah Universities. The purpose of this research is to explore the implementation of the development of al-Islam and Kemuhammadiyahan (AIK) learning through the al-Islam Intensive Lecture Training (KIAI) at the Students of Faculty of Education and Language Studies, Muhammadiyah University of Yogyakarta. The object of this research was The student in Faculty of Education and Language Studies and Al-Islam Intensive Lecturer (KIAI). This study used descriptive-analytic method by collecting information and applying observation, In-depth interview and documentation.
Highlights:

Exploration Focus: Investigating AIK learning's implementation via KIAI at Muhammadiyah University, Yogyakarta, emphasizing development.

Methodology: Descriptive-analytic approach utilizes observation, interviews, and documentation for comprehensive insight into AIK learning.

Educational Impact: Study on Faculty of Education and Language Studies students and KIAIs highlights AIK learning's significance in nurturing Islamic and Muhammadiyah characteristics in university education.

Keywords: Implementation of Al-Islam, Kemuhammadiyahan Learning, KIAI Training
Polymer Solution Preparation, Quality Control, and Produced Fluid Analysis at Milne Point
Authors: Aitkulov Almas , Redwine Connor , Alvord Jeremy , Edwards Reid , Seright R. S. 
Published: August 2024

SummaryThis paper focuses on solution preparation and quality control activities associated with the Milne Point polymer flood on the North Slope of Alaska. This project uses 10 different polymer injection locations with a variety of skid types and configurations, which had a notable impact on polymer quality control and dissolution operations. Compared with bulk 500-kg to 750-kg polymer bags, silos greatly improved the storage capacity and increased the overall quality of the polymer solutions. Silos required less physical effort when transferring polymer. Polymer hydration skids that were made in-house by the polymer supplier were more reliable and experienced fewer polymer solution quality and startup issues than those that were outsourced. These in-house skids also used a uniform programming software that made it relatively easy to train the operators on new hydration skids. For pumping polymer mother solution, triplex pumps provided the best runtime and were most maintenance-friendly, compared with diaphragm or triple screw pumps. Because of the soluble iron present in the polymer makeup water, nitrogen blanketing was preferred to minimize corrosion and oxidative degradation. Inline static mixers were ineffective in mixing mother solution with dilution water when the mixing occurred close to the wellhead. Mixing the two streams too close to the wellhead led to substantial variations in wellhead viscosity measurements. Dedicating individual pumps for injection into a given well provided desirable flexibility in controlling rates and concentrations of polymer for the well. Monitoring produced salinity and polymer concentration provided useful insights about improved sweep and polymer retention associated with the polymer flood. The observed field behavior was consistent with laboratory studies, indicating a “tailing” phenomenon associated with polymer retention at Milne Point.
Experiments on Steam-Assisted Gravity Drainage with Coinjection of Noncondensable Gases during the Middle and Later Stages of Its Development in Super-Heavy Oil Reservoirs
Authors: Zhong Lei , Zhou You , Liu Peng , Liu Pengcheng , Luo Chihui , He Wanjun , Hua Daode , Wang Chao 
Published: August 2024

Summary
The problems of oil/steam ratio (OSR) and oil production decline are prominent during the middle/later stages of steam-assisted gravity drainage (SAGD) in superheavy oil reservoirs. Using noncondensable gas (NCG) by SAGD can reduce heat loss to the overburden and reduce carbon dioxide (CO2) emissions. However, to date, laboratory experiments have mainly been conducted to simulate NCG coinjection with steam in the early stage of SAGD. There has been limited research on the NCG coinjection into the mature SAGD steam chamber. For this study, five sets of 2D physical simulation experiments are introduced and designed based on NCG coinjection with steam into the sand-packed model. The influencing factors of steam-assisted and gas push (SAGP) are analyzed through experiments, including different NCGs [methane (CH4), CO2, and nitrogen (N2)] and coinjection of NCG at different times (i.e., during the lateral expansion and descending stages of the steam chamber). The results indicate that the mechanism of SAGP includes reducing the steam consumption, maintaining the pressure balance of the steam chamber, reducing the partial pressure of the steam, maintaining the quality of the steam, and improving the displacement efficiency of the steam during the lateral expansion of the steam chamber. In addition, the top gravity displacement is the primary mechanism during the later stage of pure gas injection, which manifests that the residual oil at the bottom of the steam chamber is further recovered by using the residual heat of the the steam chamber. Compared with SAGD, the recovery of CO2-assisted SAGD (CA-SAGD), CH4-assisted SAGD (MA-SAGD), and N2-assisted SAGD (NA-SAGD) increased 6.8%, 5.4%, and 4.4%, respectively. The NCG coinjection effect was better during the descending stage of steam chamber, and the oil recovery was 4.7% higher than that during the lateral expansion stage. The selection of NCG and coinjection timing plays a crucial role in improving the ultimate oil recovery and OSR during the middle and later stages of SAGD in superheavy oil reservoirs.
Genomic regions associated with spot blotch resistance in elite barley breeding populations
Authors: Roy Dipika , Dinglasan Eric , Fowler Ryan , Platz Greg , Lance Reg , Synman Lisle , Franckowiak Jerome , Hickey Lee Thomas , Voss-Fels Kai , Robinson Hannah 
Published: August 2024

Abstract

Spot blotch (SB) is a common foliar disease of barley, caused by the hemibiotrophic fungal pathogen Bipolaris sorokiniana. Predominately found in humid growing regions worldwide, the disease can cause yield losses of up to 30%. Genetic control through deployment of durable resistance in barley cultivars is the preferred, yet the majority of Australian cultivars are susceptible, despite the identification of major resistance loci in bi-parental studies. In this study, we explore the genetic architecture of spot blotch resistance in an Australian barley breeding program. Seedling (glasshouse) and adult (field) experiments using a single conidial isolate (SB61) were conducted across two consecutive years for 337 lines genotyped with 16,824 polymorphic DArT-seq™ markers. Two mapping approaches were investigated, a single-marker genome-wide association study (GWAS) and a haplotype-based local genomic estimated breeding values (GEBV) approach. Both methods detected two major regions on chromosomes 3H and 7H that contribute resistance across growth stages. Additional chromosomal regions on 1H, 3H and 6H were detected only in the local GEBV approach. Haplotype stacking revealed the importance of the 7H region for adult-plant resistance in combination with other resistance haplotypes, suggesting a significant gene by gene interaction and demonstrating the highly quantitative nature of the genetic control. Our study validates the presence of major spot blotch resistance loci in Australian breeding populations, while generating novel insight into the genetic architecture, and highlights the challenges and opportunities to improve resistance levels via haplotype stacking or whole-genome approaches.
Dynamic oxygen assessment techniques enable determination of anesthesia’s impact on tissue
Authors: Clark Megan A. , Tavakkoli Armin D. , Petusseau Arthur F. , Scorzo Augustino V. , Kheirollah Alireza , Davis Scott C. , Strawbridge Rendall R. , Bruza Petr , Pogue Brian W. , Gladstone David J. , Hoopes P. Jack 
Published: August 2024

Abstract

Tissue oxygenation is well understood to impact radiosensitivity, with reports demonstrating a significant effect of breathing condition and anesthesia type on tissue oxygenation levels and radiobiological response. However, the temporal kinetics of intracellular and extracellular oxygenation have never been quantified, on the timescale that may affect radiotherapy studies. C57BL/6 mice were anesthetized using isoflurane at various percentages or ketamine/xylazine (ket/xyl: 100/10 mg/kg) (N = 48). Skin pO2 was measured using Oxyphor PdG4 and tracked after anesthetization began. Oxyphor data was validated with relative measurements of intracellular oxygen via protoporphyrin IX (PpIX) delayed fluorescence (DF) imaging. Ex vivo localization of both PdG4 Oxyphor and PpIX were quantified. Under all isoflurane anesthesia conditions, leg skin pO2 levels significantly increased from 12–15 mmHg at the start of anesthesia induction (4–6 minutes) to 24–27 mmHg after 10 minutes (p < 0.05). Ketamine/xylazine anesthesia led to skin pO2 maintained at 15–16 mmHg throughout the 10-minute study period (p < 0.01). An increase of pO2 in mice breathing isoflurane was demonstrated with Oxyphor and PpIX DF, indicating similar intracellular and extracellular oxygenation. These findings demonstrate the importance of routine anesthesia administration, where consistency in the timing between induction and irradiation may be crucial to minimizing variability in radiation response.
Are second-level literature reviews reliable? An assessment through bibliometric and network analysis
Authors: Klaser Klaudijo , Casari Paolo , Cuel Roberta 
Published: August 2024

Abstract

It has been estimated that in the last 30 years over 64 million scientific manuscripts were published, with the number of publications recently showing an exponential growth. Therefore, it becomes crucial to find effective ways to synthesize and systematize in a reliable way all the knowledge produced and published so far, also to identify new potential research gaps. Among the various methods devised to organize the scientific literature (narrative reviews, integrative reviews, systematic literature reviews, meta-analysis, meta-synthesis, bibliometric reviews, etc.) second-level literature reviews – that is literature reviews of previous literature reviews – represent an increasingly diffuse practice. But how reliable is this method in representing the underlying literature of the field under inquiry? Investigating the second-level literature review on flexible work arrangements (FWAs) by Toscano and Zappalà (2020) as a paradigmatic example and taking advantage of bibliometric and network analysis tools, we corroborate this research practice. With this study, we prove that second-level literature reviews are a reliable method to provide an overview of the core knowledge within a given research field, including management and organization studies.
Investigation of antifibrotic properties of lithium as a potential treatment agent for idiopathic pulmonary fibrosis and comparing its antifibrotic activity with standard of care drugs for IPF
Authors: Idelevich Pavel , Reed Kenneth 
Published: August 2024

Abstract

Background
In this study, we examined in a proprietary in vitro system the antifibrotic properties of lithium and its modulating effect on telomere maintenance and telomerase activity. Lithium effects were compared with FDA-approved drugs for the treatment of Idiopathic pulmonary fibrosis.
Methods
Lithium in three different concentrations, Nintedanib and Pirfenidone were tested in InMatrico IPF assay (Xylyx Bio) using a decellularized extracellular matrix obtained from a human lung with Idiopathic pulmonary fibrosis added with primary lung fibroblasts. After 72 hours of drug treatment samples were collected for gene expression analysis and protein secretion analysis.
Results
Lithium statistically significantly decreased the expression of two out of three tested pro-fibrotic genes. Nintedanib statistically significantly downregulated the expression of one out of three pro-fibrotic genes. Pirfenidone did not decrease the expression of pro-fibrotic genes tested in this study. Lithium and FDA-approved drugs upregulated the expression of genes related to telomere maintenance. lithium and Nintedanib exhibit a statistically significant upregulating effect on gene related to telomerase activity. Pirfenidone did not show such activity. Lithium in a dose-dependent, statistically significant manner suppresses profibrotic protein secretion. Nintedanib demonstrated a similar activity. Pirfenidone treatment failed to do so.
Conclusions
Lithium in the present study demonstrated the ability to modulate major factors related to lung fibrosis development and progression favorably, better or comparable to the “gold standard” drugs.