bluuebunny/crossref_metadata_2025_split huggingface dataset:
Home ranges, habitat selection, and energy expenditure of Strix varia (Barred Owls): Understanding the full diel cycle matters for enhancing urban landscapes
Authors: Jirinec Vitek , Bresnan Alessandra M , Clément Marion A , Colón Melanie R , Long Ashley M , Rhyne Garrett S , Rodrigues Patricia F , Stein Eliza D , Pérez-Umphrey Anna A , Varian Christina P , Williams S Tyler , Taylor Sabrina S 
Published: August 2024

Abstract
We integrated GPS and accelerometer data to examine habitat selection and energy expenditure patterns across the diel cycle in Strix varia (Barred Owls), addressing a critical gap in wildlife research that often overlooks activity during the “inactive” phase. Owls in Baton Rouge, Louisiana, selected forests with tall canopies and open understories, particularly in affluent neighborhoods, supporting the “luxury effect” in urban biodiversity. Nocturnal home ranges were larger (31.8 ha) compared to diurnal home ranges (8.9 ha), indicating broader habitat use at night. The total area of preferred nocturnal habitat was 33% of the Baton Rouge study area, whereas preferred diurnal habitat comprised only 5%. Energy expenditure was inversely related to preference in nocturnal home ranges but increased with preference in diurnal home ranges. Our models were validated using independent data from Clemson, South Carolina, supporting the robustness of our analysis and revealing generalities in owl habitat selection across these regions. This research contributes to a deeper understanding of urban ecology, highlighting habitat components preferred by owls and possibly other forest-dwelling species. It emphasizes the difference in nocturnal and diurnal home range sizes, the scarcity of daytime refuges for S. varia in urban landscapes, and the variation in energy expenditure in preferred habitats. Our findings advocate for urban designs that accommodate wildlife activity throughout the day and night, and highlight the positive correlation between preferred owl habitat and affluent neighborhoods, underscoring the need for equitable distribution of green spaces to foster biodiversity across socioeconomic gradients. These insights will help develop strategies to enhance the ecological value of urban environments and the conservation of S. varia and associated forest-dwelling species in rapidly urbanizing areas.
Quantifying the emergence of moral foundational lexicon in child language development
Authors: Ramezani Aida , Liu Emmy , Lee Spike W S , Xu Yang 
Published: August 2024

Abstract
Theorists have argued that morality builds on several core modular foundations. When do different moral foundations emerge in life? Prior work has explored the conceptual development of different aspects of morality in childhood. Here, we offer an alternative approach to investigate the developmental emergence of moral foundations through the lexicon, namely the words used to talk about moral foundations. We develop a large-scale longitudinal analysis of the linguistic mentions of five moral foundations (in both virtuous and vicious forms) in naturalistic speech between English-speaking children with ages ranging from 1 to 6 and their caretakers. Using computational methods, we collect a dataset of 1,371 human-annotated moral utterances and automatically annotate around one million utterances in child-caretaker conversations. We discover that in childhood, words for expressing the individualizing moral foundations (i.e. Care/Harm, Fairness/Cheating) tend to emerge earlier and more frequently than words for expressing the binding moral foundations (i.e. Authority/Subversion, Loyalty/Betrayal, Purity/Degradation), and words for Care/Harm are expressed substantially more often than the other foundations. We find significant differences between children and caretakers in how often they talk about Fairness, Cheating, and Degradation. Furthermore, we show that the information embedded in childhood speech allows computational models to predict moral judgment of novel scenarios beyond the scope of child-caretaker conversations. Our work provides a large-scale documentation of the moral foundational lexicon in early linguistic communication in English and forges a new link between moral language development and computational studies of morality.
A legend in one's own mind: The link between ambition and leadership evaluations
Authors: Alzahawi Shilaan , Reit Emily S , Flynn Francis J 
Published: August 2024

Abstract
Individuals who have more ambition—a persistent striving for success, attainment, and accomplishment—are more likely to become leaders. But are these ambitious individuals also more effective in leadership roles? We hypothesize that leader ambition is related to positive self-views of leader effectiveness that remain uncorroborated by relevant third-party actors. In a multiwave, preregistered study, we find evidence for this hypothesis using a sample of executives (N = 3,830 ratings of 472 leaders) who were rated by peers, subordinates, managers, and themselves on ten leadership competencies, including their ability to motivate others, manage collaborative work, coach and develop people, and present and communicate ideas. We consider the implications of our findings for both scholars and practitioners interested in leadership selection and development.
Correcting misperceptions of partisan opponents is not effective at treating democratic ills
Authors: Dias Nicholas C , Aarslew Laurits F , Frederiksen Kristian Vrede Skaaning , Lelkes Yphtach , Pradella Lea , Westwood Sean J 
Published: August 2024

Abstract
Many warn that the United States is on the brink of democratic collapse, because partisan animosity, support for partisan violence, and support for undemocratic practices are on the rise. Quelling some fears, scholars have offered interventions that use messages to correct misperceptions about citizens’ partisan opponents (the “out-party”). In this article, we provide evidence that the effects of these interventions are not as robust or consistent as hoped. First, we use panel data (n=9,810) to show that perceptions of the out-party are highly variable. This suggests that these perceptions are weakly held and thus unlikely to be a significant cause of hostile attitudes. The oscillation of perceptions over time also suggests that, for many, any effect of corrections would likely be overwhelmed in just 1 month. Second, in a meta-analysis of 67 statistical tests from 12 studies in eight papers, we document that current evidence on the efficacy of corrections is weak. Third and finally, in pre-registered experiments (n=2,846), we find that changing Americans’ perceptions of the out-party’s demographics, policy attitudes, and support for undemocratic practices has no consistent effect on partisan animosity, support for partisan violence, or support for undemocratic practices. These observations suggest that correcting misperceptions of the out-party is not a panacea for our democratic ills.
Balancing Equitable Enforcement and Property Rights: Revisiting Section 23 of the Maintenance and Welfare of Parents and Senior Citizens Act, 2007 of India
Authors: Yadav Mohit , Pathak Gaurav , Ganesh Anush 
Published: August 2024

Abstract
The Maintenance and Welfare of Parents and Senior Citizens Act, 2007 (hereinafter “MWPSC Act”) of India, specifically section 23, addresses the responsibility of heirs towards their parents’ maintenance and the consequences of failure in such obligations. This article critically evaluates the interpretation and application of section 23, focusing on the judicial reasoning, implications on property rights, and comparisons with international jurisprudence. The article proposes a balanced approach to ensure equitable enforcement while safeguarding third-party interests and the broader legal landscape. It advocates for a nuanced understanding of the statute, emphasizing the need for explicit conditions, limitations on resorting to section 23, and harmonizing maintenance obligations with property rights. Drawing from foreign legal systems, this article underscores the uniqueness of Indian legislation while highlighting the absence of similar provisions in other jurisdictions. By analysing the interpretation and application of section 23 of the MWPSC Act, this article contributes to the broader discourse on balancing legislative intent, public policy, familial obligations, and property rights in the context of elder care in India.
Efficacy and safety of mesenchymal stem cell therapies for ischemic stroke: a systematic review and meta-analysis
Authors: Shen Zhiyuan , Tang Xian , Zhang Yaxin , Jia Yicun , Guo Xin , Guo Xiaosu , Bao Junqiang , Xie Xiongwei , Xing Yuan , Xing Jun , Tian Shujuan 
Published: August 2024

Abstract

Background
The efficacy and safety of mesenchymal stem cells (MSCs) in the treatment of ischemic stroke (IS) remains controversial. Therefore, this study aimed to evaluate the efficacy and safety of MSCs for IS.

Methods
A literature search until May 23, 2023, was conducted using PubMed, EMBASE, the Cochrane Library, and the Web of Science to identify studies on stem cell therapy for IS. Interventional and observational clinical studies of MSCs in patients with IS were included, and the safety and efficacy were assessed. Two reviewers extracted data and assessed the quality independently. The meta-analysis was performed using RevMan5.4.

Results
Fifteen randomized controlled trials (RCTs) and 15 non-randomized trials, including 1217 patients (624 and 593 in the intervention and control arms, respectively), were analyzed. MSCs significantly improved patients’ activities of daily living according to the modified Rankin scale (mean difference [MD]: −0.26; 95% confidence interval [CI]: −0.50 to −0.01; P = .04) and National Institutes of Health Stroke Scale score (MD: −1.69; 95% CI: −2.66 to −0.73; P &lt; .001) in RCTs. MSC treatment was associated with lower mortality rates in RCTs (risk ratio: 0.44; 95% CI: 0.28-0.69; P &lt; .001). Fever and headache were among the most reported adverse effects.

Conclusions
Based on our review, MSC transplantation improves neurological deficits and daily activities in patients with IS. In the future, prospective studies with large sample sizes are needed for stem cell studies in ischemic stroke. This meta-analysis has been registered at PROSPERO with CRD42022347156.
Hierarchical Heuristic Species Delimitation Under the Multispecies Coalescent Model with Migration
Authors: Kornai Daniel , Jiao Xiyun , Ji Jiayi , Flouri Tomáš , Yang Ziheng 
Published: August 2024

Abstract
The multispecies coalescent (MSC) model accommodates genealogical fluctuations across the genome and provides a natural framework for comparative analysis of genomic sequence data from closely related species to infer the history of species divergence and gene flow. Given a set of populations, hypotheses of species delimitation (and species phylogeny) may be formulated as instances of MSC models (e.g., MSC for 1 species versus MSC for 2 species) and compared using Bayesian model selection. This approach, implemented in the program bpp, has been found to be prone to over-splitting. Alternatively, heuristic criteria based on population parameters (such as population split times, population sizes, and migration rates) estimated from genomic data may be used to delimit species. Here, we develop hierarchical merge and split algorithms for heuristic species delimitation based on the genealogical divergence index (gdi) and implement them in a Python pipeline called hhsd. We characterize the behavior of the gdi under a few simple scenarios of gene flow. We apply the new approaches to a dataset simulated under a model of isolation by distance as well as 3 empirical datasets. Our tests suggest that the new approaches produced sensible results and were less prone to oversplitting. We discuss possible strategies for accommodating paraphyletic species in the hierarchical algorithm, as well as the challenges of species delimitation based on heuristic criteria.
Rethinking non-conformity of a serious nature: From the CISG and the PICC’s concept of fundamental breach towards a Nachfrist principle—learning from the amendments to Catalan sales law’s cure regime
Authors: Mirambell Fargas Miquel 
Published: August 2024

Abstract
Whereas the European Commission’s endeavours to codify European contract law are at an impasse, the harmonization effect of European Union (EU) Directive 2019/771 should not be under-estimated. Such effect extends beyond consumer legislation and is particularly remarkable in EU jurisdictions that did not enact ad hoc consumer acts. This article takes the amendments to Catalan sales law after the transposition of Article 13 of the Directive as a benchmark. It delves into the recently introduced seriousness threshold under Article 13(4) lit. (c) of the Directive as an additional basis for contract avoidance in case of the delivery of non-conforming goods. The article further discusses whether such a serious nature threshold should (or can) coexist with the previous notion of fundamental breach and rethinks the contours of these legal thresholds from a cure perspective.
The Soybean Cyst Nematode Effector Cysteine Protease 1 (CPR1) Targets a Mitochondrial Soybean Branched-Chain Amino Acid Aminotransferase (GmBCAT1)
Authors: Margets Alexandra , Foster Jessica , Kumar Anil , Maier Tom R. , Masonbrink Rick , Mejias Joffrey , Baum Thomas J. , Innes Roger W. 
Published: August 2024

The soybean cyst nematode (SCN; Heterodera glycines) facilitates infection by secreting a repertoire of effector proteins into host cells to establish a permanent feeding site composed of a syncytium of root cells. Among the diverse proteins secreted by the nematode, we were specifically interested in identifying proteases to pursue our goal of engineering decoy substrates that elicit an immune response when cleaved by an SCN protease. We identified a cysteine protease that we named Cysteine Protease 1 (CPR1), which was predicted to be a secreted effector based on transcriptomic data obtained from SCN esophageal gland cells, the presence of a signal peptide, and the lack of transmembrane domains. CPR1 is conserved in all isolates of SCN sequenced to date, suggesting it is critical for virulence. Transient expression of CPR1 in Nicotiana benthamiana leaves suppressed cell death induced by a constitutively active nucleotide binding leucine-rich repeat protein, RPS5, indicating that CPR1 inhibits effector-triggered immunity. CPR1 localizes in part to the mitochondria when expressed in planta. Proximity-based labeling in transgenic soybean roots, co-immunoprecipitation, and cleavage assays identified a branched-chain amino acid aminotransferase from soybean (GmBCAT1) as a substrate of CPR1. Consistent with this, GmBCAT1 also localizes to mitochondria. Silencing of the CPR1 transcript in the nematode reduced penetration frequency in soybean roots, while the expression of CPR1 in soybean roots enhanced susceptibility. Our data demonstrates that CPR1 is a conserved effector protease with a direct target in soybean roots, highlighting it as a promising candidate for decoy engineering. [Formula: see text] Copyright © 2024 The Author(s). This is an open access article distributed under the CC BY-NC-ND 4.0 International license .
The interplay between lymphatic vessels and macrophages in inflammation response
Authors: Zhou Cheng , Sun TianYi , Dong ZiQing , Lu Feng , Li Bin 
Published: August 2024

AbstractBoth lymphatic vessels and macrophages are key factors influencing the inflammatory response. During the inflammatory response, lymphatic vessels undergo dilation and growth, playing a beneficial role in alleviating inflammation by facilitating the drainage of exudate, inflammatory mediators, and leukocytes. Consequently, the promotion of lymphangiogenesis has emerged as a novel therapeutic approach to treating inflammation. Macrophages play a crucial role in promoting lymphangiogenesis by secreting several pro‐lymphatic growth factors, including vascular endothelial growth factor (VEGF)‐C, and undergoing transdifferentiation into lymphatic endothelial cell progenitors (LECP), which integrate into newly formed lymphatic vessels. Macrophages exhibit heterogeneity and perform diverse functions based on their phenotypes. The regulation of macrophage polarization is crucial in inflammatory responses. Notably, macrophages promote lymphangiogenesis, while lymphatic vessels, in turn, serve as a conduit for macrophages to drain out inflamed tissue and also affect macrophage polarization. Thus, there is an interactive relationship between them. In this review, we discuss current work on the effects of macrophages on lymphangiogenesis as well as lymphatic vessel recruitment of macrophages and regulation of macrophage polarization. Furthermore, we explore the roles of lymphatic vessels and macrophages in various inflammation‐related diseases, emphasizing potential therapeutic targets within the context of lymphatic–macrophage interactions.
Transcriptome and proteome changes triggered by overexpression of the transcriptional regulator Maf1 in the human pathogen Leishmania major
Authors: Rivera‐Rivas Luis A. , Florencio‐Martínez Luis E. , Romero‐Meza Gabriela , Ortega‐Ortiz Roberto C. , Manning‐Cela Rebeca G. , Carrero Julio C. , Nepomuceno‐Mejía Tomás , Martínez‐Calvillo Santiago 
Published: August 2024

AbstractMaf1, originally described as a repressor of RNA polymerase III (RNAP III) transcription in yeast, participates in multiple functions across eukaryotes. However, the knowledge about Maf1 in protozoan parasites is scarce. To initiate the study of Maf1 in Leishmania major, we generated a cell line that overexpresses this protein. Overexpression of Maf1 led to a significant reduction in the abundance of tRNAs, 5S rRNA, and U4 snRNA, demonstrating that Maf1 regulates RNAP III activity in L. major. To further explore the roles played by Maf1 in this microorganism, global transcriptomic and proteomic changes due to Maf1 overexpression were determined using RNA‐sequencing and label‐free quantitative mass spectrometry. Compared to wild‐type cells, differential expression was observed for 1082 transcripts (615 down‐regulated and 467 up‐regulated) and 205 proteins (132 down‐regulated and 73 up‐regulated) in the overexpressing cells. A correlation of 44% was found between transcriptomic and proteomic results. Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses revealed that the differentially expressed genes and proteins are mainly involved in transcription, cell cycle regulation, lipid metabolism and transport, ribosomal biogenesis, carbohydrate metabolism, autophagy, and cytoskeleton modification. Thus, our results suggest the involvement of Maf1 in the regulation of all these processes in L. major, as reported in other species, indicating that the functions performed by Maf1 were established early in eukaryotic evolution. Notably, our data also suggest the participation of L. major Maf1 in mRNA post‐transcriptional control, a role that, to the best of our knowledge, has not been described in other organisms.
Research progress on interferon and cellular senescence
Authors: Wang Da , Chen Kaixian , Wang Zheng , Wu Huali , Li Yiming 
Published: August 2024

AbstractSince the 12 major signs of aging were revealed in 2023, people's interpretation of aging will go further, which is of great significance for understanding the occurrence, development, and intervention in the aging process. As one of the 12 major signs of aging, cellular senescence refers to the process in which the proliferation and differentiation ability of cells decrease under stress stimulation or over time, often manifested as changes in cell morphology, cell cycle arrest, and decreased metabolic function. Interferon (IFN), as a secreted ligand for specific cell surface receptors, can trigger the transcription of interferon‐stimulated genes (ISGs) and play an important role in cellular senescence. In addition, IFN serves as an important component of SASP, and the activation of the IFN signaling pathway has been shown to contribute to cell apoptosis and senescence. It is expected to delay cellular senescence by linking IFN with cellular senescence and studying the effects of IFN on cellular senescence and its mechanism. This article provides a review of the research on the relationship between IFN and cellular senescence by consulting relevant literature.
Evaluating the Knowledge Levels and Attitudes Regarding Pressure Injuries among Nurses in Turkey
Authors: Şahan Seda , Güler Sevil 
Published: August 2024

ABSTRACT

OBJECTIVE
To determine nurses’ knowledge levels and attitudes regarding pressure injury (PI) in Turkey and to reveal the relationship between these two variables.

METHODS
This study was conducted with 604 nurses to obtain 98% power based on the G*Power analysis. The authors used the Pressure Ulcer Knowledge Assessment Tool (PUKAT) 2.0 and Attitude toward Pressure Ulcer Prevention (APuP) instrument for data collection. Regression, correlation analysis, independent-sample t test, and analysis of variance were used in data analysis.

RESULTS
Nurses’ mean total PUKAT 2.0 score was 9.40 ± 2.47 (46.72% correct). Nurses’ mean total score on the APuP instrument was 32.39 ± 2.752. The total knowledge score and total attitude score were positively correlated (ρ = 0.761; P = .007). According to the results of linear regression analysis, the demographic variables of sex, education, seniority, and unit significantly predicted PUKAT 2.0 scores and APuP scores.

CONCLUSIONS
Nurses’ knowledge of PI prevention was insufficient, and their attitudes were average. A significant and positive relationship was identified between nurses’ knowledge and attitudes regarding PI.