bluuebunny/crossref_metadata_2025_split huggingface dataset:
Interdisciplinarity in cultural gerontology and geriatric medical humanities – a bibliometric survey
Authors: Waldron Emily , Wakefield Katherine , O'Neill Desmond 
Published: August 2024

Abstract

Purpose Cultural gerontology – understanding ageing through the lens of arts and humanities - has emerged as an important element of epistemology of ageing. As a boundary area between geriatric medicine/gerontology and arts/humanities disciplines, joint-working/interdisciplinarity is desirable. This project aims to assess the degree of joint-working manifested in cultural gerontology by authorship and acknowledgements in papers dedicated to cultural gerontology in five journals.Methods Observational survey of authorship in 5 journals from the founding of the specific sections on cultural gerontology or specific dedicated journals, assessing number of authors, disciplinary identities, and evidence of joint working within cultural gerontology.Results Of 591 papers, 481 (81%) were single authors. There was a spread of disciplinary affiliations, 247 (41.8%) gerontology/age-studies, 169 arts/humanities/social sciences (28.6%) and 133 of uncertain affiliation (22.5%): only 38 papers had a clear indication of joint working across the disciplines (6.4%). In the two geriatric medicine journals, European Geriatric Medicine and Journal of the American Geriatrics Society, authorship was almost exclusively from geriatric medicine/gerontology. There was extremely limited use of acknowledgements.Conclusion Our study indicates that single authorship is the most frequent mode of peer-reviewed publishing in cultural gerontology, while acknowledging that some authors may have scholarly training in multiple fields but are listed as unidisciplinary. Leaders in the field and editors of relevant journals/section need to consider ways of encouraging and recognising joint working, through fuller descriptions of multiple affiliations, brief author biographies, fuller use of acknowledgements and consideration of brief accompanying discussant responses from complementary disciplines.
Positive influence of apple trees on soil chemical and biological activity in an agroecological garden orchard system
Authors: Ramananjatovo T. , Guénon R. , Peugeot J. , Chantoiseau E. , Delaire M. , Buck-Sorlin G. , Guillermin P. , Cannavo P. 
Published: August 2024

Abstract

The specific aim of this study was to assess the impact of 20-year-old apple trees on the soil agronomic quality in an agroforestry system consisting of 2 rows of apple trees with 5 rows of vegetable beds in between. The effects of this system were analyzed specifically on soil microbial activity and fertility. Measurements were carried out for 2 years between 2019 and 2021 in apple tree rows (R) and in vegetable rows 1.5 m (B1), 3 m (B2) and 5 m (C) from the apple tree row. Litter quantities and soil organic matter (SOM) content were measured as well as the decomposition rates of apple tree leaf litter. Soil microbial activity was characterized by measuring (1) in-situ soil respiration and (2) basal (BR) and substrate induced respiration (SIR) under controlled conditions. The results showed that proximity to apple trees was linked to higher SOM content. The litter decomposition rate was up to 1.7-times greater under the tree rows than in vegetable beds. The amplitude of insitu soil CO2 flux variation and the maximum flux were lower under the tree rows than in vegetable beds, mainly due to lower temperature. In the vegetable beds, the maximum in-situ soil CO2 flux was attained faster in B1 than in C. Under controlled laboratory conditions, we showed that BR was significantly stronger in R, B1 and B2 than in C (5, 5, 4.7 and 3.5 µgC-CO2.h− 1.g− 1 soil DW, respectively). In addition, the soil in the apple tree rows was more sensitive to the addition of glucose (SIR) than the soil in the vegetable beds. Our results suggest that soil microbial activity was more intensive up to 3 m from the apple trees. Globally, the results highlight the complexity of the interactions among the biotic and abiotic factors that are at the origin of the spatial heterogeneity encountered.
Wireless Blockchain based Dual Auction Method for Peer-to-Peer Energy Exchange on Microgrid
Authors: Divya G , Supraja P 
Published: August 2024

Abstract

Decentralized energy trading stands as a significant avenue for enhancing the utilization of Sustainable Energy (SE) resources within the Grid network, while simultaneously mitigating losses associated with extensive grid infrastructure. Four distinct dual auction scheme, including Trade Reduction, McAfee, Vickrey Clarke Groves (VCG), and Average, aim to improve the efficiency of decentralized peer-to-peer energy exchange. This research work systematically assessed these mechanisms in a range of forms of microgrid (MG). Participants can specify how much they are willing to spend on various energy modules on varying period that incorporates user priority, bidding methods, and time of use tariffs. In most MG configurations, the Average and VCG processes were shown to be the most efficient. In particular, it was discovered that the average mechanism worked best for a market-focused MG, but the VCG mechanism was mostly beneficial for trading outside of peak hours. This work provides a thorough approach that skillfully determines and suggests the best auction procedures for various MG configurations and consumption schedules, opening the door for extra effective P2P energy exchange.
Enzymatic Synthesis of Reactive RNA Probes Containing Squaramate-Linked Cytidine for Bioconjugations and Cross-Linking with Lysine-Containing Peptides and Proteins
Authors: Hocek Michal , Ivancová Ivana , Ondrus Marek , Sanchez-Quirante Tania , Pohl Radek , Vlkova Marta , Žilecká Eva , Bouřa Evžen 
Published: August 2024

Abstract

We designed and synthesized cytidine 5′-O-triphosphate bearing a reactive squaramate group attached to position 5 of pyrimidine (CESQTP) and used it as substrate for polymerase synthesis of modified RNA. In vitro transcription with T7 RNA polymerase or primer extension using engineered TGK DNA polymerase were used for synthesis of RNA probes bearing one to eight reactive modifications. The squaramate moiety speficially reacts with primary amines to form stable amide bond. Thus, the reactive RNA probes underwent bioconjugations with amine-linked fluorophore or with a lysine-containing peptide. Cross-linking reactions of squaramate-modified RNA probes with RNA-binding proteins including several viral RNA polymerases or HIV reverse transcriptase proceeded with moderate to good conversions. Inhibition of RNA-depending RNA polymerases from Japanese Encephalitis virus through formation of covalent cross-link has also been observed and the cross-link was partially identified by MS/MS analysis. Thus, the squaramate-linked CTP is a useful building block for the synthesis of reactive RNA probes for bioconjugations with amines and cross-linking with lysine residues.
Towards Resilient Pipeline Infrastructure: Lessons Learned from Failure Analysis
Authors: Silva Ana , Evangelista Luís , Ferreira Cláudia , Valença Jónatas , Mendes Maria Paula 
Published: August 2024

Abstract

Understanding the mechanisms of pipeline failures is crucial for identifying vulnerabilities in gas transmission pipelines and planning strategies to enhance the reliability and resilience of energy supply chains. Existing studies and the American Society of Mechanical Engineers’ (ASME) Code for Pressure Piping primarily focus on corrosion, recommending inspections every 10 years to prevent incidents due to this time-dependent threat. However, these guidelines do not provide comprehensive regulation on the likelihood of incidents due to other causes, especially non-time-dependent events (i.e. do not provide any indication of the inspection frequency or the most likely time for an incident to occur). This study adopts an innovative approach adopting machine learning, particularly Artificial Neural Networks (ANNs), to analyse historical pipeline failure data from 1970 to 2023. By analysing records from the US Pipeline & Hazardous Materials Safety Administration, the model captures the complexity of various degradation phenomena, predicting failure years and hazard frequencies beyond corrosion. This innovative approach allows adopting more informed preventive measures and response strategies, offering deep insights into incident causes, consequences, and patterns. The results deliver valuable information for maintenance planning, enabling the estimation of critical times when a pipeline may be susceptible to incidents due to various factors. This study provides operators with a strategic framework to prescriptively address potential vulnerabilities, thereby promoting sustained operational integrity and minimising the occurrence of unexpected events throughout the service life of pipelines. By expanding the scope of risk assessment beyond corrosion, this study significantly advances the field of pipeline safety and reliability, setting a new standard for comprehensive incident prevention.
Prevalence and impact of a protein-truncating POMC variant on obesity in the Estonian Biobank
Authors: Abner Erik , Batool Kanwal , Taba Nele , Nikopensius Tiit , Läll Kristi , Alekseienko Anastasiia , Eriksson Anders , Rämö Joel , Kariis Hanna Maria , Haljasmägi Liis , Võsa Urmo , Tillmann Taavi , Vainik Uku , Lehto Kelli , Kisand Kai , Esko Tōnu , Team Estonian Biobank Research 
Published: August 2024

Abstract

Population-specific genome-wide association studies can reveal high-impact genomic variants that influence traits like body-mass index (BMI). Using the Estonian Biobank BMI dataset (n=204,747 participants) we identified 214 genome-wide significant loci. Among those hits, we identified a common non-coding variant within the newly associated ADGRL3 gene (-0.18 kg/m²; P = 3.06 × 10⁻⁹). Moreover, the missense rare variant PTPRT:p.Arg1384His associated with lower BMI (-0.44 kg/m²; P = 2.5 × 10⁻¹⁰), while the protein-truncating variant POMC:p.Glu206* was associated with considerably higher BMI (+0.81 kg/m²; P = 1.5 × 10-12), both likely affecting the functioning of the leptin-melanocortin pathway. POMC:p.Glu206* was observed in different North-European populations, suggesting a broader, yet elusive, distribution of this damaging variant. These observations indicate the novel roles of the ADGRL3 and PTPRT genes in body weight regulation and suggest an increased prevalence of the POMC:p.Glu206* variant in European populations, offering avenues for developing interventions in obesity management.
The landscape of immune cell infiltration and potential biomarkers in intervertebral disc degeneration
Authors: Wang Yuanhao , Hu Bingtao , Tian Lijun , Feng Xiangling , Wang Guohua , Liu Gang , Du Lilong , Xu Haiwei , Kang Yuxiang , Li Guowang , Xu Baoshan 
Published: August 2024

Abstract

Background
Immune cell infiltration has been found to be strongly associated with the occurrence and progression of intervertebral disc degeneration (IDD), and intervertebral discs (IVDs) are immune-privileged organs. This research aimed to identify novel targets for therapeutic intervention and investigate significant physiological and cellular mechanisms involved in the immune infiltration processes of IDD.
Results
CIBERSORT deconvolution analysis revealed that the levels of follicular helper T cells and M2 macrophages were significantly increased during IDD, while the levels of resting mast cells were significantly decreased. WGCNA revealed that the blue module was associated with macrophage infiltration (positive correlation 0.87, P < 0.001), of which genes, including VAMP8, TLR4, JUN, PLA2G4A, NMI, RORA, IFNGR1, IFNGR2, NINJ1, TNIP1, and CD81, were mainly enriched in macrophage activation, myeloid leukocyte activation and the Toll-like receptor 4 signaling pathway. The proportion of leukocytes in the IVD was greatest on the 14th day after puncture. Single-cell sequencing revealed the division of degenerative IVD cells into seven major cell types, annulus fibrosus cells, smooth muscle cells, fibroblasts, macrophages, monocytes, vascular endothelial cells, and NP cells, in which Jun, Cd81, Rora, Vamp8, Ninj1, and Tnip1 were strongly expressed, western blotting results in normal and degenerated nucleus pulposus cells (NNP and DNP) showed that the expression of VAMP8 and c-Jun increased after 24 hours of stimulation with 50 ng/ml TNF-α. The immunohistochemical results showed an increase in VAMP8 and c-Jun levels in the IVD of rats on the 14th day after acupuncture.
Conclusion
The 14th day after acupuncture in the IVD of rats is a crucial time point for the infiltration of immune cells. This work is the first to reveal that VAMP8 and c-Jun are linked to the infiltration of macrophages in IDD. Elevated expression of VAMP8 and c-Jun was confirmed in both DNP and punctured rat IVDs.
Development and validation of a machine learning-based predictive model for compassion fatigue in nursing interns: A cross-sectional study with latent profile analysis
Authors: Yi Lijuan , Shuai Ting , Liu Yi , Zhou Jingjing , Jiménez-Herrera Maria F. , Tian Xu 
Published: August 2024

Abstract

Background
Exposure to compassion fatigue during internships can significantly impact on nursing students’ future career trajectories and their intention to stay in the nursing profession. Accurately identifying nursing students at high risk of compassion fatigue is vital for timely interventions. However, existing assessment tools often fail to account for within-group variability and lack predictive capabilities. To develop and validate a predictive model for detecting the risk of compassion fatigue among nursing students during their placement.
Design:
A cross-sectional study design.
Methods
Data from 2256 nursing students in China between December 2021 and June 2022 were collected on compassion fatigue, professional identity, self-efficacy, social support, psychological resilience, coping styles, and demographic characteristics. The latent profile analysis was performed to classify compassion fatigue levels of nursing students. Univariate analysis, least absolute shrinkage and selection operator regression analysis were conducted to identify potential predictors of compassion fatigue. Eight machine learning algorithms were selected to predict compassion fatigue, and the performance of these machine learning models were evaluated using calibration and discrimination metrics. Additionally, the best-performing model from this evaluation was selected for further independent assessment.
Results
A three-profile model best fit the data, identifying low (55.73%), moderate (32.17%), and severe (12.10%) profiles for compassion fatigue. The area under the curve values for the eight machine learning models ranged from 0.644 to 0.826 for the training set and from 0.651 to 0.757 for the test set. The eXtreme Gradient Boosting performed best, with area under the receiver operating characteristic curve values of 0.840, 0.768, and 0.731 in the training, validation, and test sets, respectively. SHAP analysis clarified the model’s explanatory variables, with psychological resilience, professional identity, and social support being the most significant contributors to the risk of compassion fatigue. A user-friendly, web-based prediction tool for calculating the risk of compassion fatigue was developed.
Conclusions
The eXtreme Gradient Boosting classifier demonstrates exceptional performance, and clinical implementation of the online tool can provide nursing managers with an effective means to manage compassion fatigue.
WITHDRAWN: Orientation-dependent magnetic properties and anomalous Hall effect in half-metallic NiCo2O4 thin films
Authors: Xu Zedong , Bai Zhijin , Li Xiaowen , Wang Yuming , Liu Qi , Hu Sixia , Zhu Yuanmin , Jiang Yong , Chen Lang 
Published: August 2024

Abstract

The proliferation of spintronic devices necessitates the advancement of novel material platforms, particularly those featuring ferrimagnetic and antiferromagnetic properties. Among them, NiCo2O4 (NCO), a ferrimagnetic material, stands out for its half-metallic band structure and remarkable attributes like robust perpendicular magnetic anisotropy, a high Curie temperature, and tunable film characteristics through conductivity modulation. These unique features render NCO a prime candidate for spintronics applications. Here, we focus on the orientation-dependent magnetic properties and transport behavior of epitaxial NCO films grown on (001)-, (110)-, and (111)-oriented MgAl2O4 substrates. Notably, NCO films with different epitaxial orientations exhibit significant differences in magnetic anisotropy and transport behavior. Specifically, the (110)-oriented NCO samples present a field-driven spin reorientation transition in the out-of-plane direction, resulting in a split hysteresis loop and corresponding longitudinal magnetoresistance and anomalous Hall curves. Importantly, the anomalous Hall effect (AHE) of (100) and (111)-oriented NCO films displays an opposite sign, while the AHE of (110)-oriented NCO films exhibits an unusual sign reversal at approximately 150 K, distinguishing them from other magnetic oxides. With these findings, NCO films offer a novel platform for fundamental AHE research, featuring tunable AHE signs and intriguing physical mechanisms. Additionally, by introducing an antiferromagnetic NiO layer, we achieve a significant exchange-bias effect and enhanced coercive field, holding immense potential for future spintronics applications, such as ferrimagnetic high-density memories.
Fatigue failure of incorporated crack HTPB(Hydroxyl-terminated polybutadiene) propellant under strain control
Authors: Li Genfeng , Gao Bo , Hu Hao , Cui Ruifu , Feng Jiwei , He Jian 
Published: August 2024

Abstract

To study the fatigue properties of incorporated crack HTPB (hydroxyl terminated polybutadiene propellant) propellant under strain control, fatigue tests with different strain amplitudes were carried out on the MTS fatigue testing machine. Four groups of specimens were set up in this test, namely one group with specimens and three groups with incorporated crack specimens with different angles (0°/45°/75°/ to the horizontal) of cracks. During the fatigue test, an infrared camera was used to monitor the temperature of the whole test piece in the whole process. The results show that at the same frequency, the increase of the strain amplitude will shorten the fatigue life. The fatigue life of the three incorporated crack specimens is similar reaching at 20000times, all in the same order of magnitude, and the fatigue life of the un-cracked specimen is larger reaching at 100000times, showing a cross-order phenomenon. In the fatigue test, the samples exhibit obvious strain hysteresis phenomenon and has significant viscoelastic material properties, in terms of the surface temperature monitoring of the specimens, the four groups of specimens all show a trend of temperature increase, and the final surface temperature and fatigue life are positive related.
Nematicidal plants for root-knot nematode (Meloidogyne spp.) management in vegetable cropping systems
Authors: Njekete Cliven , Caravel Claire , Massol François , Lavoir Anne-Violette , Djian-Caporalino Caroline 
Published: August 2024

Abstract

Root-knot nematodes (RKN), Meloidogyne species, are a top global threat associated with economic crop yield losses. They are difficult to detect and control, especially given the recent restrictions on environmentally harmful chemicals. Thus, there is a need for alternative solutions for sustainable RKN management, such as nematicidal plants (non-hosts or poor hosts). Despite the advanced literature, the information for nematicidal plant species, cultivars, and specific RKN species is incomplete or inconsistent. We evaluated the host suitability of 28 nematicidal plant candidates in controlled climate chambers using a susceptible tomato and pepper as controls. The assessment was based on gall and egg mass counts after one RKN cycle. All screened candidates were less infected with M. incognita, M. arenaria, and M. enterolobii than tomatoes, suggesting all the candidates are either non/ poor hosts, except Allium fistulosum. Only Tagetes patula and T. erecta were consistently non-hosts to the three RKN species. Other candidates exhibited RKN species-specificity and varied in their poor host or non-host status depending on the variety. Selected nematicidal plants were further assessed for RKN juvenile penetration and had significantly lower M. incognita penetration than tomato. However, Crotalaria juncea had significantly higher M. incognita penetration than tomato. This suggests that the tested plants inhibit root penetration of most M. incognita juveniles at the rhizosphere level while C. juncea attracts the nematodes and restricts reproduction. There is potential for most of the nematicidal plants to be used in cropping systems for sustainable integrated RKN management.
Longitudinal study of symptom clusters in lung cancer patients with refractory cancer pain during treatment
Authors: He Yuling , Lin Meiqun , Xu Zhenhua , Luo Huiyu , Zhu Hongyu 
Published: August 2024

Abstract

Now temporarily not seen for lung cancer patients with intractable pain symptom group of related research. The aim of this study is to explore the morphology of symptom clusters in patients with refractory lung cancer pain during treatment, and to reflect the changing characteristics of symptom clusters in patients with refractory lung cancer pain. Using Chinese MD Anderson symptom scale and the revised module, lung cancer at baseline (T1), after treatment 2 weeks (T2), 1 month after treatment (T3), and 3 months after treatment (T4) to measure the following four differences of a variety of symptoms.Through exploratory factor analysis to determine the symptom group. A total of 218 lung cancer patients with refractory cancer pain participated in the study. Six symptom clusters were identified at four time points (somatic-psychological SC, gastrointestinal SC, lung cancer-specific SC, adverse effect SC, sleep deprivation SC, and respiratory SC). Of the six symptom clusters, four remained stable at all time points, and there were differences in symptom clusters at different stages of treatment. Lung cancer number than other types of cancer in patients with refractory pain symptoms, severity and troubled degrees were heavier, different time point, symptoms of existing relative stability, and in dynamic change.
In-Plane Quasi-Static Cyclic Testing of Rc Frames Retrofitted With Rigid/Dissipating Steel Haunches
Authors: Ilyas Babar , Jan Faizullah , Khedher Khaled Mohamed , Ullah Arif , Bilal Hazrat , Sarir Muhammad , Alam Muhammad , Kujawa Marcin 
Published: August 2024

Abstract

This research assessed the reliability of haunch retrofitting technique for seismic upgrade of critically damaged frames. Two 1:3 reduced scale two-story RC frames were taken under considered, which were tested previously till the near collapse state. The haunches are employed to strengthen the joint shear strength of the badly damaged joints, which are indicative of old, non-seismic, or defective joints. Damaged concrete was replaced with new high-strength concrete, and haunch-retrofitting technique was adopted to strengthen beam-column connections, in order to avoid shear hinging at joints under lateral loads. The retrofitted frames were tested through quasi-static cyclic loads in a displacement-control condition for multiple-levels of roof drifts. In order to assess the following seismic response factors: stiffness, strength, ductility, and response modification factors—lateral force-displacement capacity curves were created and examined. Hysteretic responses of tested models were analyzed to quantify hysteretic damping. The seismic performance assessment of the retrofitted frames was conducted utilizing a code-based static force approach in multiple seismic zones. The rigid haunches contributed to the over strength factor while the dissipating haunch has major contribution in energy dissipation of the retrofitted frames.