bluuebunny/crossref_metadata_2025_split huggingface dataset:
AUTOMORPHISM GROUPS OF SELF-COMPLEMENTARY VERTEX-TRANSITIVE GRAPHS
Authors: HUANG ZHAOHONG , PAN JIANGMIN , DING SUYUN , LIU ZHE 
Published: November 2015

Li et al. [‘On finite self-complementary metacirculants’, J. Algebraic Combin.40 (2014), 1135–1144] proved that the automorphism group of a self-complementary metacirculant is either soluble or has $\text{A}_{5}$ as the only insoluble composition factor, and gave a construction of such graphs with insoluble automorphism groups (which are the first examples of self-complementary graphs with this property). In this paper, we will prove that each simple group is a subgroup (so is a section) of the automorphism groups of infinitely many self-complementary vertex-transitive graphs. The proof involves a construction of such graphs. We will also determine all simple sections of the automorphism groups of self-complementary vertex-transitive graphs of $4$-power-free order.
Attentional bias modification (ABM) training induces spontaneous brain activity changes in young women with subthreshold depression: a randomized controlled trial
Authors: Li H. , Wei D. , Browning M. , Du X. , Zhang Q. , Qiu J. 
Published: November 2015

BackgroundAttention bias modification (ABM) training has been suggested to effectively reduce depressive symptoms, and may be useful in the prevention of the illness in individuals with subthreshold symptoms, yet little is known about the spontaneous brain activity changes associated with ABM training.MethodResting-state functional MRI was used to explore the effects of ABM training on subthreshold depression (SubD) and corresponding spontaneous brain activity changes. Participants were 41 young women with SubD and 26 matched non-depressed controls. Participants with SubD were randomized to receive either ABM or placebo training during 28 sessions across 4 weeks. Non-depressed controls were assessed before training only. Attentional bias, depressive severity, and spontaneous brain activity before and after training were assessed in both training groups.ResultsFindings revealed that compared to active control training, ABM training significantly decreased depression symptoms, and increased attention for positive stimuli. Resting-state data found that ABM training significantly reduced amplitude of low-frequency fluctuations (ALFF) of the right anterior insula (AI) and right middle frontal gyrus which showed greater ALFF than non-depressed controls before training; Functional connectivity strength between right AI and the right frontoinsular and right supramarginal gyrus were significantly decreased after training within the ABM group; moreover, the improvement of depression symptoms following ABM significantly correlated with the connectivity strength reductions between right AI and right frontoinsular and right supramarginal gyrus.ConclusionThese results suggest that ABM has the potential to reshape the abnormal patterns of spontaneous brain activity in relevant neural circuits associated with depression.
The Boussinesq Debate: Reversibility, Instability, and Free Will
Authors: Michael Mueller Thomas 
Published: November 2015

ArgumentIn 1877, a young mathematician named Joseph Boussinesq presented amémoireto theAcadémiedes sciences which demonstrated that some differential equations may have more than one solution. Boussinesq linked this fact to indeterminism and to a possible solution to the free will versus determinism debate. Boussinesq's main interest was to reconcile his philosophical and religious views with science by showing that matter and motion do not suffice to explain all there is in the world. His argument received mixed criticism that addressed both his philosophical views and the scientific content of his work, pointing to the physical “realisticness” of multiple solutions. While Boussinesq proved to be able to face the philosophical criticism, the scientific objections became a serious problem, thus slowly moving the focus of the debate from the philosophical plane to the scientific one. This change of perspective implied a wide discussion on topics such as instability, the sensitivity to initial conditions, and the conservation of energy. The Boussinesq debate is an example of a philosophically motivated debate that transforms into a scientific one, an example of the influence of philosophy on the development of science.
Gastrointestinal, influenza-like illness and dermatological complaints following exposure to floodwater: a cross-sectional survey in The Netherlands
Authors: DE MAN H. , MUGHINI GRAS L. , SCHIMMER B. , FRIESEMA I. H. M. , DE RODA HUSMAN A. M. , VAN PELT W. 
Published: November 2015

SUMMARYExtreme rainfall events may cause pluvial flooding, increasing the transmission of several waterborne pathogens. However, the risk of experiencing clinically overt infections following exposure to pluvial floodwater is poorly estimated. A retrospective cross-sectional survey was performed to quantify the occurrence of self-reported gastrointestinal, influenza-like illness (ILI) and dermatological complaints, and the frequency of visits to the general practitioner (GP), during a 4-week observation period following pluvial flooding at seven locations in The Netherlands. Questionnaires were sent to 817 flooded households, 149 (17%) of which returned the questionnaire reporting information for 199 participants. Contact with floodwater was significantly associated with increased occurrence of gastrointestinal [odds ratio (OR 4·44)], ILI (OR 2·75) and dermatological (OR 6·67) complaints, and GP visits (OR 2·72). Having hand contact with floodwater was associated with gastrointestinal and dermatological complaints, whereas ILI complaints were associated with being engaged in post-flooding cleaning operations and having walked/cycled through floodwater. This study shows that floodwater-associated diseases occur in urban settings following extreme rainfall events in a high-income country. As pluvial floods are expected to escalate in the future due to global climate change, further research is warranted to determine the disease burden of pluvial flooding and to assess the effect of different interventions, including raising awareness among stakeholders.
Research and Evaluations of the Health Aspects of Disasters, Part V: Epidemiological Disaster Research
Authors: Birnbaum Marvin L. , Daily Elaine K. , O’Rourke Ann P. 
Published: November 2015

AbstractStudies of the health aspect of disasters focus either on the epidemiology of disasters to define the causes and the progression from a hazard to a disaster, or the evaluations of interventions provided during any phase of a disaster. Epidemiological disaster research studies are undertaken for the purposes of: (1) understanding the mechanisms by which hazards evolve into a disaster; (2) determining ways to mitigate the risk(s) that a specific hazard will progress into a disaster; (3) predicting the likely damages and needs of the population-at-risk for an event; and (4) identifying potential measures to increase the resilience of a community to future events. Epidemiological disaster research utilizes the Conceptual, Temporal, and Societal Frameworks to define what occurs when a hazard manifests as an event that causes a disaster. The findings from such studies should suggest interventions that could augment the absorbing, buffering, or/and response capacities to lessen the probability of similar damages occurring from the next event. Ultimately, the use of these Frameworks in studying the health aspects of a disaster will help define what to expect in a specific setting and the standards and best practices upon which education, training, competencies, performance, and professionalization will be built.BirnbaumML, DailyEK, O’RourkeAP. Research and evaluations of the health aspects of disasters, part V: epidemiological disaster research. Prehosp Disaster Med.2015;30(6):648–656.
contamDE: differential expression analysis of RNA-seq data for contaminated tumor samples
Authors: Shen Qi , Hu Jiyuan , Jiang Ning , Hu Xiaohua , Luo Zewei , Zhang Hong 
Published: November 2015

AbstractMotivation: Accurate detection of differentially expressed genes between tumor and normal samples is a primary approach of cancer-related biomarker identification. Due to the infiltration of tumor surrounding normal cells, the expression data derived from tumor samples would always be contaminated with normal cells. Ignoring such cellular contamination would deflate the power of detecting DE genes and further confound the biological interpretation of the analysis results. For the time being, there does not exists any differential expression analysis approach for RNA-seq data in literature that can properly account for the contamination of tumor samples.Results: Without appealing to any extra information, we develop a new method ‘contamDE’ based on a novel statistical model that associates RNA-seq expression levels with cell types. It is demonstrated through simulation studies that contamDE could be much more powerful than the existing methods that ignore the contamination. In the application to two cancer studies, contamDE uniquely found several potential therapy and prognostic biomarkers of prostate cancer and non-small cell lung cancer.Availability and implementation: An R package contamDE is freely available at http://homepage.fudan.edu.cn/zhangh/softwares/.Contact: zhanghfd@fudan.edu.cnSupplementary information: Supplementary data are available at Bioinformatics online.
Realtime analysis and visualization of MinION sequencing data with npReader
Authors: Cao Minh Duc , Ganesamoorthy Devika , Cooper Matthew A. , Coin Lachlan J. M. 
Published: November 2015

Abstract
Motivation: The recently released Oxford Nanopore MinION sequencing platform presents many innovative features opening up potential for a range of applications not previously possible. Among these features, the ability to sequence in real-time provides a unique opportunity for many time-critical applications. While many software packages have been developed to analyze its data, there is still a lack of toolkits that support the streaming and real-time analysis of MinION sequencing data.
Results: We developed npReader, an open-source software package to facilitate real-time analysis of MinION sequencing data. npReader can simultaneously extract sequence reads and stream them to downstream analysis pipelines while the samples are being sequenced on the MinION device. It provides a command line interface for easy integration into a bioinformatics work flow, as well as a graphical user interface which concurrently displays the statistics of the run. It also provides an application programming interface for development of streaming algorithms in order to fully utilize the extent of nanopore sequencing potential.
Availability and implementation: npReader is written in Java and is freely available at https://github.com/mdcao/npReader.
Contact: m.cao1@uq.edu.au or l.coin@imb.uq.edu.au
Dispatch from the non-HITECH–incented Health IT world: electronic medication history adoption and utilization
Authors: Gabriel Meghan Hufstader , Smith Jaime Y , Sow Max , Charles Dustin , Joseph Seth , Wilkins Tricia Lee 
Published: November 2015

Objective To document national trends of electronic medication history use in the ambulatory setting and describe the characteristics and predicting factors of providers who regularly use medication history transaction capabilities through their e-prescribing systems.Materials and Methods The study used provider-initiated medication history data requests, electronically sent over an e-prescribing network from all 50 states and the District of Columbia. Data from 138,000 prescribers were evaluated using multivariate analyses from 2007 to 2013.Results Medication history use showed significant growth, increasing from 8 to 850 million history requests during the study period. Prescribers on the network for &lt;5 years had a lower likelihood of requests than those on the network for 5 or more years. Although descriptive analyses showed that prescribers in rural areas were alongside e-prescribing, and requesting medication histories more often than those in large and small cities, these findings were not significant in multivariate analyses. Providers in orthopedic surgery and internal medicine had a higher likelihood of more requests than family practice prescribers, with 12% and 7% higher likelihood, respectively.Discussion Early adopters of e-prescribing have remained medication history users and have continually increased their volume of requests for medication histories.Conclusion Despite the fact that the use of medication histories through e-prescribing networks in the ambulatory care setting has not been encouraged through federal incentive programs, there has been substantial growth in the use of medication histories offered through e-prescribing networks.
How cold atoms got hot: an interview with William Phillips
Authors: Ball Philip 
Published: November 2015

Abstract
William Phillips of the National Institute of Standards and Technology (NIST) in Gaithersburg, Maryland, shared the 1997 Nobel Prize in physics for his work in developing laser methods for cooling and trapping atoms. Interactions between the light field and the atoms create what is dubbed an ‘optical molasses’ that slows the atoms down, thereby reducing their temperature to within a fraction of a degree of absolute zero. These techniques allow atoms to be studied with great precision, for example measuring their resonant frequencies for light absorption very accurately, so that these frequencies may supply very stable timing standards for atomic clocks. Besides applications in metrology, such cooling methods can also be used to study new fundamental physics. The 1997 Nobel award was widely considered to be a response to the first observation in 1995 of pure Bose–Einstein condensation (BEC), in which a collection of bosonic atoms all occupy a single quantum state. This quantum-mechanical effect only becomes possible at very low temperatures, and the team that achieved it, working at JILA operated jointly by the University of Colorado and NIST, used the techniques devised by Phillips and others. Since then, cold-atom physics has branched in many directions, among them being attempts to make a quantum computer (which would use logic operations based on quantum rules) from ultracold trapped atoms and ions. ‘National Science Review’ spoke with Phillips about the development and future potential of the field.
Near-infrared spectroscopy of quasars at z ∼ 3 and estimates of their supermassive black hole masses
Authors: Saito Yuriko , Imanishi Masatoshi , Minowa Yosuke , Morokuma Tomoki , Kawaguchi Toshihiro , Sameshima Hiroaki , Minezaki Takeo , Oi Nagisa , Nagao Tohru , Kawatatu Nozomu , Matsuoka Kenta 
Published: November 2015

Abstract
We present the results of new infrared spectroscopic observations of 37 quasars at z ∼ 3, selected based on the optical r ′-band magnitude and the availability of nearby bright stars for future imaging follow-up with an adaptive optics system. The supermassive black hole (SMBH) masses (MBH) were successfully estimated in 28 out of 37 observed objects from the combination of the Hβ emission linewidth and continuum luminosity at rest-frame 5100 Å. Comparing these results with those from previous studies of quasars with similar redshift, our sample exhibited slightly lower Eddington ratios (∼−0.11 dex in median), and the SMBH masses are slightly higher (∼0.38 dex in median). The SMBH growth time, tgrow, was calculated by dividing the estimated SMBH mass by the mass accretion rate measured using optical luminosity. We found, given reasonable assumptions, that tgrow was smaller than the age of the universe at the redshift of individual quasars for a large fraction of observed sources, suggesting that the SMBHs in many of our observed quasars are in the growing phase with high accretion rates. A comparison of the SMBH masses derived from our Hβ data and archived C iv data indicated considerable scattering, as indicated in previous studies. All quasars with measured SMBH masses have at least one nearby bright star, such that they are suitable targets for adaptive optics observations to study the mass relationship between SMBHs and host galaxies’ stellar components at high redshift.
The Subaru COSMOS 20: Subaru optical imaging of the HST COSMOS field with 20 filters
Authors: Taniguchi Yoshiaki , Kajisawa Masaru , Kobayashi Masakazu A. R. , Shioya Yasuhiro , Nagao Tohru , Capak Peter L. , Aussel Herve , Ichikawa Akie , Murayama Takashi , Scoville Nick Z. , Ilbert Olivier , Salvato Mara , Sanders David B. B. , Mobasher Bahram , Miyazaki Satoshi , Komiyama Yutaka , Le Fèvre Olivier , Tasca Lidia , Lilly Simon , Carollo Marcella , Renzini Alvio , Rich Michael , Schinnerer Eva , Kaifu Norio , Karoji Hiroshi , Arimoto Nobuo , Okamura Sadanori , Ohta Kouji , Shimasaku Kazuhiro , Hayashino Tomoki 
Published: November 2015

Abstract
We present both the observations and the data reduction procedures of the Subaru COSMOS 20 project, an optical imaging survey of the HST COSMOS field, carried out by using Suprime-Cam on the Subaru Telescope with the following 20 optical filters: six broad-band (B, g′, V, r′, i′, and z′), two narrow-band (NB711 and NB816), and 12 intermediate-band filters (IA427, IA464, IA484, IA505, IA527, IA574, IA624, IA679, IA709, IA738, IA767, and IA827). Part of this project is described in Taniguchi et al. (2007, ApJS, 172, 9) and Capak et al. (2007, ApJS, 172, 99) for the six broad-band and one narrow-band (NB816) filter data. In this paper, we present details of the observations and data reduction for the remaining 13 filters (the 12 IA filters and NB711). In particular, we describe the accuracy of both the photometry and astrometry in all the filter bands. We also present the optical properties of the Suprime-Cam IA filter system in appendices.
Utility of Postoperative Antibiotics After Percutaneous Pinning of Pediatric Supracondylar Humerus Fractures
Authors: Schroeder Nicholas O. , Seeley Mark A. , Hariharan Arun , Farley Frances A. , Caird Michelle S. , Li Ying 
Published: November 2015

Background:
Pediatric supracondylar humerus fractures are common injuries that are often treated surgically with closed reduction and percutaneous pinning. Although surgical-site infections are rare, postoperative antibiotics are frequently administered without evidence or guidelines for their use. With the increasing prevalence of antibiotic-resistant organisms and heightened focus on health care costs, appropriate and evidence-based use of antibiotics is needed. We hypothesized that postoperative antibiotic administration would not decrease the rate of surgical-site infection.

Methods:
A billing query identified 951 patients with operatively treated supracondylar humerus fractures at our institution over a 15-year period. Records were reviewed for demographic data, perioperative antibiotic use, and the presence of surgical-site infection. Exclusion criteria were open fractures, open reduction, pathologic fractures, metabolic bone disease, the presence of other injuries that required operative treatment, and follow-up <2 weeks after pin removal. χ2 and Fisher exact test were used to compare antibiotic use to the incidence of surgical-site infection.

Results:
Six hundred eighteen patients met our inclusion criteria. Two hundred thirty-eight patients (38.5%) received postoperative antibiotics. Eleven surgical-site infections were identified for an overall rate of 1.8%. The use of postoperative antibiotics was not associated with a lower rate of surgical-site infection (P=0.883). Patients with a type III fracture (P<0.001), diminished preoperative vascular (P=0.001) and neurological status (P=0.019), and postoperative hospital admission (P<0.001) were significantly more likely to receive postoperative antibiotics.

Conclusions:
Administration of postoperative antibiotics after closed reduction and percutaneous pinning of pediatric supracondylar humerus fractures does not decrease the rate of surgical-site infection.

Level of Evidence:
Level III—therapeutic.
Klebsiella pneumoniae Hepatic Abscess and Bacteremia Despite Prophylactic Antibiotics Posttransarterial Bland Embolization
Authors: Hill Ebone' Danielle , Nanjappa Sowmya , Kis Bela 
Published: November 2015

Abstract
Transarterial embolizations have become a common treatment of both unresectable primary and metastatic liver tumors. Infectious complications of this procedure are relatively uncommon because most patients are treated with empiric broad spectrum antibiotics after the procedure. However, infections that may occur include skin infection at the puncture site, hepatic abscess, necrotizing pancreatitis, and cholecystitis. Hepatic abscess formation typically occurs in patients with previous biliary intervention and can often prove fatal. This case describes a patient with no previous biliary intervention who developed Klebsiella pneumoniae hepatic abscess and bacteremia despite prophylactic antibiotics after transarterial bland embolization of a liver metastasis.
The Myriad Advantages of Ultrasonography in Image-Guided Interventions
Authors: Copelan Alexander , Scola Dominic , Roy Anindya , Nghiem Hanh Vu 
Published: November 2015

Abstract
We will review and illustrate the multiple advantages of ultrasound as an image guidance tool, including real-time vessel visualization, multiplanar capability, portability/availability, and decreased procedure time and cost.
We will demonstrate the unique advantages of the use of this imaging modality in the biopsy of small parenchymal lesions particularly those that are not visible with unenhanced computed tomography (CT) or not persistently visible with contrast-enhanced CT or those lesions not readily accessible by CT guidance, the use of direct probe compression to displace bowel away from biopsy targets, the use of direct probe compression to staunch intraprocedural bleeding observed with real-time visualization to minimize postprocedural bleeding complications, and the ability to biopsy masses in pediatric patients as a function of the inherent lack of ionizing radiation.
Finally, we will review and illustrate how the use of preprocedural lesion characterization with ultrasound at times can serve as a problem-solving tool providing an alternative and reasonably confident diagnosis and thus avoiding unnecessary procedures and associated potential risks.
Ultrasound of Biliary Cast Syndrome and Its Mimics
Authors: Hu Bing , Horrow Mindy M. 
Published: November 2015

Abstract
Biliary cast syndrome (BCS) consists of mass-like hardened collections of inspissated bile and sloughed biliary mucosa filling the intrahepatic and/or extrahepatic bile ducts, which show an alternating pattern of dilatation and stricture. It is a rare but serious complication of liver transplantation frequently necessitating repeated percutaneous, endoscopic or surgical stent placements, and cast retrieval. Although not typically considered as the modality of choice for BCS compared with magnetic resonance cholangiopancreatography and endoscopic retrograde cholangiopancreatography, ultrasound can be quite useful for this diagnosis. This article reviews the sonographic appearance of BCS in postliver transplant patients and correlates with other imaging modalities including computed tomography, MRCP, and endoscopic retrograde cholangiopancreatography. Also reviewed are other intrahepatic pathologies that mimic the appearance of BCS on ultrasound.
Physics-based multiscale mass transport model in drug delivery and tumor microenvironment
Authors: Ziemys Arturas , Kojic Milos , Ferrari Mauro 
Published: November 2015

AbstractWe describe multiscale transport model, which was developed to simulate drug diffusion and convection in tissues and drug vectors. Models rely on material properties and physical laws of transport. Our methods show that drug transport analysis may provide deep insight into mechanisms of pharmacokinetics useful in nanotherapeutics and transport study within tumor microenvironment. Because the method relies on material properties and structures, the approach can help studying phenotypical differences as well.