bluuebunny/crossref_metadata_2025_split huggingface dataset:
A descriptive study to assess the effectiveness of planned teaching programme on knowledge related to polycystic ovarian disorder among adolescent girls of SGRR nursing college Patel Nagar, Dehradun
Authors: Bahadur Rebecca Priti , Paonam Dineshwori Chanu , Kukreti Deepti , Masih Shivani , Kukreti Aradhana 
Published: February 2025

One of the primary reasons why infertility is on the rise is Polycystic Ovarian Disorder or PCOD. It is a chronic disorder in which many benign cysts form on the ovaries. It affects about 3%-7% of women of reproductive age. It most commonly in women under 30 years old and is a commonest cause of anovulation and a leading cause of infertility. Although the precise origin of PCOD is yet unclear, genetics and hormone abnormalities are thought to have a role. In some cases, it can even run-in families. Now a days most of the adolescent girls are found suffering from PCOD due to bad food habits, sedentary lifestyle and also stress and it will affect their quality of life. Hence the researcher selected this topic for the study.: The aim of the study was to assess the effectiveness of structured teaching programme on knowledge regarding polycystic ovarian disorder among adolescent girls studying in SGRR College of nursing Patel Nagar, Dehradun. : One group pretest post-test design was adopted to evaluate the effectiveness of planned teaching program on PCOD. The sample was collected using convenient sampling technique. 60 adolescent girls of age 18-21 years were selected, [sample size was calculated with the help of Yamane’s formula n= N/ (1+Ne2)] out of which 57 girls were taken from Basic B.Sc. Nursing 1 year and 3 girls from GNM 1 year. A self-developed knowledge questionnaire consisting of 30 multiple choice questions regarding PCOD was used to collect data. The pre-test showed that 66.7% of girls had inadequate knowledge whereas after the structured teaching programme 18.4% had inadequate knowledge. In pre-test 28.34% of girls had moderate knowledge whereas 40% girls had moderate knowledge after exposure to planned teaching programme. Before the planned teaching programme very few 5% girls were having adequate level of knowledge whereas after exposure to structured teaching programme, 41.6% girls attained adequate level of knowledge. Thus, the study concluded that most of the students attained adequate knowledge after the structured teaching program which was found statistically significant (at the level of p&#60; 0.05).
Evaluation of vitamin D status in antenatal patients attending OPD at a tertiary care centre
Authors: Kaur Manpreet , Sood Reena , Pahwa Sangeeta 
Published: February 2025

Vitamin D deficiency during pregnancy is a worldwide epidemic. Studies have reported a prevalence that ranges from 18-84%, depending on country of residence, season and local clothing customs. Furthermore studies have shown that pregnancy alone is a risk factor for vitamin D deficiency particularly among women living at high altitudes.Vitamin D deficiency in pregnancy is associated with increased risk of pre eclampsia, gestational diabetes mellitus, preterm birth, small for gestational age infants, impaired fetal skeletal formation and bone mineral density (BMD). Aim of our study is to assess vitamin D levels in antenatal patients in first trimester attending OPD at a tertiary care centre.: It is a cross-sectional study that was conducted in department of OBG at SGRD, Sri Amritsar. All participants meeting inclusion criteria were enrolled for the study and written informed consent was taken. Serum sample of the eligible primigravida was taken at time of recruitment, centrifuged and stored at -70 degrees for assessment of serum 25 hydroxy-vitamin D level.: A high prevalence of vitamin D deficiency was observed in our study population where only 18.8% had adequate levels of vitamin D while 81.2% of the participants had vitamin D deficiency (69% were insufficient and 12.2% were severe deficient), and none of the participants was having vitamin D toxicity. The deficiency was equally high in all age groups of study participants irrespective of their area of residence. The mean serum calcium in severe deficient and adequate group was 7.97±0.61 and 9.22 ±0.63 respectively (p=0.001). Similarly mean serum phosphorus levels in severe deficient and adequate group is 3.03±0.79 and 3.60±0.63 respectively (p=0.001). Maternal education, socioeconomic status, obesity, serum calcium and serum phosphorus levels were significantly associated with severe vitamin D deficiency.: Vitamin D deficiency is highly prevalent among pregnant women who participated in our study, which raises concern about the health consequences for the mother and the offspring.
Prevalence of extreme preterm, very and moderate to late preterm births and their association with risk factors – in a South Indian cohort
Authors: Dharwad Farzana Begaum , Khursheed Romana , Kannan Roshni , Dalal Anita , Khan Maryum , Maldar Arif 
Published: February 2025

Given the exponential rise in preterm births around the globe, this study aims to know prevalence of overall preterm births and among different categories as well as to analyse the risk factors responsible for preterm birth in different categories. This cross-sectional study was conducted in Dr. Prabhakar Kore Charitable Hospital, Belagavi from June 2021 to May 2022. The risk factors were classified into extreme preterm, very preterm and moderate to late preterm. Chi-square test was used to check the dependency between categorical variables. Odds ratio was calculated for knowing the association of different risk factors with type of preterm birth. Among 3413 women, there were 588 (17.67%) preterm births. 479(81.46%) were in moderate to late preterm category, 71 (12.07%) were very preterm and 38(6.46%) were extremely preterm. Odds of extreme preterm for maternal single kidney, congenital anomalies, covid infection, fetal growth restriction, preeclampsia, still birth, hypothyroidism were 65.68 [95% CI: 3.09-1393.85], 10.22[ 95% CI: 3.08 -33.94], 7.93 [95% CI: 2.21-28.44], 2.83 [95% CI: 1.37-5.90], 2.42[95% CI:1.42-4.10], 2.16 [95% CI: 1.13 -4.13], 3.14 [95% CI: 1.5-6.35], 1.86 [95% CI: 0.94-3.73] respectively when compared with moderate to late preterm group. The prevalence of preterm birth was 17.6%. The risk factors should be controlled in pre conceptional period and early pregnancy to reduce preterm births.
First trimester serum uric acid as an early predictor of gestational diabetes mellitus
Authors: Bhattacharya Aritri , Patil Hema Sharanagouda 
Published: February 2025

First identified during pregnancy, GDM (Gestational diabetes mellitus) is referred by reduced glucose tolerance that results in varied degrees of hyper-glycemia. Usually, the diagnosis is made between twenty four to twenty eight weeks period of gestation. Compared to European women, South Asian, and especially Indian women have an 11 times elevated chance of developing GDM. GDM women are more prone to operative vaginal deliveries, cesarean sections, and complications such as shoulder dystocia during vaginal delivery due to the fetus having macrosomia or large for gestation. Screening and diagnostic methods for GDM depend largely on historical data, clinical examination, and laboratory tests like DIPSI and IADPSG. Early detection and prevention methods for GDM are limited. The purpose of this study was to evaluate the predictive value of serum uric acid levels in the first trimester for GDM in low-risk pregnant women. : Following obtaining permission, the level of serum uric acid had been measured from blood samples obtained from low-risk pregnant women. DIPSI testing was done twice, once between the weeks of gestation of 24 and 28 and then again between 28 and 32 weeks of gestation. Regression analysis employing receiver operating characteristic (ROC) curves and logistic regression was used to evaluate serum uric acid's capacity to predict GDM. The Youden index was utilized to establish the cut-off values. A statistically significant result was defined as having a p-value of &#60;0.05.: 106 patients who met the study's inclusion criteria were included. The level of Serum uric acid in the 1 trimester had an AU-ROC of 0.8316 with a cut-off &#62; 3.4 mg/dl, meaning 74.70% sensitivity and 82.61% specificity for GDM prediction. Serum uric acid and GDM showed a significant correlation (p &#60; 0.001), according to logistic regression. Individuals whose level of serum uric acid is &#62;3.4mg/dl had 14.02 times greater odds of suffering from GDM (95% CI: 4.28 - 45.92) than those with serum uric acid ≤ 3.4.: A one-year observational study conducted at the Dr. Prabhakar Kore Charitable Hospital and Research Centre, Belgaum, on behalf of KAHER revealed that the improvement of GDM can be predicted early with a 1 trimester serum uric acid cutoff of higher than 3.4 mg/dl.
A case series on navigating ovarian cysts during pregnancy assess the outcomes
Authors: Ethirajan Shanthi , Yalamaddi Ooha Dharani , Janarthanam Samya 
Published: February 2025

Ovarian cysts are a common incidental finding during pregnancy, often presenting a diagnostic and management challenge due to concerns regarding maternal and fetal outcomes. This case series aims to explore the management strategies and outcomes of ovarian cysts detected during pregnancy. A total of 5 cases were included in the case series. The mean maternal age was 25 years, with cysts predominantly identified in the second trimester. The majority of cysts were simple or functional. Diagnostic ultrasound was the primary modality for cyst characterization. Management strategies varied from expectant management to surgical intervention depending on cyst size, symptoms, and growth patterns. Maternal complications were rare, with 1 case showing ovarian torsion. Fetal outcomes were favorable, for 3 out of 5 cases. This case series highlights the importance of tailored management approaches for ovarian cysts detected during pregnancy. Conservative management is generally safe, with favorable maternal and fetal outcomes observed in most cases. Close surveillance with serial imaging remains crucial to monitor cyst progression and guide clinical decision-making. Further prospective studies are warranted to establish evidence-based guidelines for optimal management of ovarian cysts in pregnant patients.
Mercado de trabalho, discriminação racial e Justiça do Trabalho no Estado do Rio de Janeiro: o racismo como tema residual?
Authors: Santos Sales Augusto dos 
Published: February 2025

Este artigo descreve e analisa três dos quatro processos sobre discriminação racial no ambiente de trabalho que foram ajuizados por trabalhadores/as contra quatro empresas, entre 1995 e 2005, no Tribunal Regional do Trabalho da 1ª Região-TRT01, localizado no Estado do Rio de janeiro, mas que chegaram à última instância da Justiça Trabalhista, o Tribunal Superior do Trabalho (TST). Constata-se que há disparidade entre um considerável índice de discriminação racial no mercado de trabalho nacional e a baixa quantidade de denúncias pelos/as trabalhadores/as do crime de racismo junto à Justiça do Trabalho, especialmente na do Rio de Janeiro. Como o escopo de fontes primárias é reduzido para o caso do TRT01, não concluiremos, isto é, descreveremos e analisaremos um resultado concreto, mas levantamos a hipótese de que o tema racismo contra os/as trabalhadores/as negros/as foi tratado de forma residual e/ou marginal pelos membros da Justiça do Trabalho, no período supracitado, o que tem prejudicado sobremaneira esses/as trabalhadores/as não somente no Estado do Rio de Janeiro, mas em todas as Unidades da Federação. Pensamos que essa a limitação de dados primários não inviabiliza a necessidade de uma reflexão séria sobre o tema racismo na Justiça Trabalhista do Rio Janeiro, até porque ela precisa ser feita, inclusive para que este assunto não continue marginal na Justiça do Trabalho como um todo.
Comparison between Micro Sandblaster and Direct Flame Technique for Removing Adhesive Remnants from Debonded Orthodontic Metal Bracket Bases
Authors: Wang Sally , Galvan Shirchie Iris 
Published: February 2025

Background: The removal methods of adhesive resin remain a subject of debate among researchers regarding the most effective approach for reconditioning debonded brackets from the tooth.
Objectives: The aim of this study was to evaluate the micro sandblaster and direct flame technique for removing adhesive remnants from debonded orthodontic metal bracket bases.
Method: The research design was experimental and involved comparing the micro sandblaster and direct flame technique in removing adhesive remnant using purposive sampling. Thirty (30) metal brackets were divided into two groups and soaked for 24 hours in an incubator before applying the two methods of removal. The samples were examined in optical microscopy, and the areas of adhesive remnants were analyzed and measured as a percentage of the digital images using the ImageJ analysis software function. Pixels were converted into millimeters (mm). Statistical analyses, including Shapiro-Wilk Test, Levene’s Test, and T-Test for Independent samples were conducted.
Results: The micro sandblaster group exhibited the lowest mean value at 1.518 mm +1.159 (mean + standard deviation), while the direct flame group showed the highest value at 2.264 mm +1.262. The Levene’s Test result was 0.079, and the T-Test for Independent Samples yielded a p-value of 0.103 which exceeded the predetermined significance level of 0.05.
Conclusion: The results of this study indicate that the micro sandblaster and direct flame techniques for removing adhesive residues from debonded metal brackets showed statistically insignificant differences. Either of these methods may be a viable approach for operators to use when reconditioning dislodged brackets.
Fabrication and mechanical performance of bark cloth/glass fiber reinforced hybrid polymer composites for automotive applications
Authors: Alibet Frances , Wambua Paul , Githinji David Njuguna , Rwahwire Samson , Bongomin Ocident 
Published: February 2025

Abstract

This study investigates the mechanical properties of hybrid composites reinforced with bark cloth (Ficus natalensis) and glass fiber in a polyester resin matrix. Composites were fabricated using the hand layup technique with varying fiber weight fractions (15%, 20%, and 25%) and hybrid ratios (3:1, 2:2, 1:3). The influence of hybrid ratio and stacking sequence on flexural, tensile, compressive, and impact strengths was evaluated. Results indicated that composites with higher glass fiber content exhibited superior mechanical performance, with optimal flexural (140.94 MPa), tensile (43.24 MPa), compressive (26.47 MPa), and impact strengths (32.44 kJ/m²) at a 1:3 hybrid ratio. Hybridization improved the mechanical properties of the composites, particularly flexural strength, which was significantly affected by stacking sequence. These findings suggest that bark cloth/glass fiber hybrid composites have potential for applications in automotive and structural industries.
Integrated electrodialysis/electro-oxidation process for the treatment of chlorpyrifos wastewater with high energy efficiency
Authors: Tu Yong , Chen Yong , Zhang Xiaoyue , Xu Yunhao , Zhang Yixuan , Cui Tao , Fu Boming 
Published: February 2025

ABSTRACT

A novel integration of the electrochemical process with electrodialysis and electro-oxidation (IEDEO) was designed for the effective pretreatment of chlorpyrifos manufacturing wastewater, with high concentrations of both salts and organic compounds. The effects of operating parameters including initial pH and constant voltage on the IEDEO process performance were investigated. The IEDEO process showed excellent performance for the simultaneous removal of bio-refractory organics and inorganics in the chlorpyrifos wastewater. In contrast with the single EO process, the results of energy consumption, UV–vis spectra, and GC–MS showed that the oxidation performance for chlorpyrifos wastewater by IEDEO was carried out more efficiently. The biodegradability of the chlorpyrifos wastewater pretreated by IEDEO was significantly improved. The total salt removal (90.3 ± 2.1%) from the chlorpyrifos wastewater obtained by IEDEO was significantly higher than the 5.8 ± 1.6% removal attained with the EO process. The COD removal of chlorpyrifos wastewater by the IEDEO process was 25.5 ± 1.2%, and the energy consumption of the IEDEO process was 15.1 ± 1.6 kWh kg−1 COD at 2 h, representing a 60–65% reduction compared to the EO process. This indicated that the IEDEO process was a valuable pretreatment technique for biological treatment. Moreover, scanning electron microscopy and X-ray diffraction results demonstrated that the IEDEO concentrate was beneficial for subsequent evaporative desalination.
Prevalence and Usage of Dietary Supplements among Teenagers in Chennai: A Cross-sectional Study
Authors: Muppa Leena , Shathriya S Gokul , Alan A. Darius , Aadhithan D. S. , Kaushik K. 
Published: February 2025

Introduction: The use of dietary supplements is increasingly common among teenagers globally, driven by a variety of motivations such as perceived health benefits, peer influence, and body image concerns. Dietary supplements include vitamins, minerals, amino acids, and herbal products intended to supplement one's diet and promote health. However, inappropriate or excessive use of these supplements can pose health risks, particularly in adolescents who may lack sufficient information about proper dosage and potential side effects. This study aims to analyze the prevalence and usage patterns of dietary supplements among teenage students in Chennai. Methods and Materials: This cross-sectional study was carried out for a period of 6 months from May to October 2024. A semi structured questionnaire was used to collect data and a total of 175 responses analysed using descriptive statistics with statistical significance, p-value < 0.05. Results: Approximately 60% of the participants reported using dietary supplements. Among the users, 65% were male, and 35% were female, indicating a higher prevalence of dietary usage among male teenagers. A significant difference in supplement use was observed between medical and non-medical students. The most commonly used supplements were multivitamins, protein powders, and omega-3 fatty acids. Medical students showed a higher usage of specific supplements, possibly due to greater awareness of health benefits. Most students reported using supplements for general health improvement, increased energy, and enhanced physical appearance. Medical students more frequently cited specific health benefits and disease prevention as reasons for use. Conclusion: This study indicates a high prevalence of dietary supplement use among teenagers in Chennai, with a notable gender difference and higher usage rates among medical students. The findings suggest that medical students, possibly due to their academic training, may have a heightened awareness of dietary supplements' potential benefits. However, the widespread use of supplements among teenagers, especially for aesthetic reasons, underscores the need for health education that informs adolescents about safe and effective use. Schools, parents, and healthcare providers should collaborate to ensure that teenagers have access to reliable information, minimizing the risks associated with unsupervised supplement intake.
Keywords: Dietary supplements, Protein, Vitamin, Teenagers
Protein Engineering: A Novel Approach in Vaccine Development
Authors: Adhikari Diwas , Pokhrel Sharada 
Published: February 2025

Due to advances in biotechnology, immunology and molecular biology, protein engineering has been an innovative technique for the development, optimization and production of vaccine. Deliberate alternation in the protein structure causes the improvement or change in the properties of the protein and due to this approach modification of the antigens for inducing the strong immune response is possible thus creating a benchmark in vaccine development. Recombinant DNA Technology, Epitope Mapping, Molecular Display Systems, Fusion Proteins and Designing of virus like particles are some of the key techniques in the protein engineering. Development of the various vaccines such as Hepatitis B vaccine, HPV Vaccine and Covid-19 Vaccine are some of the successes of protein engineering approach. However, there are some challenges associated with the techniques such as Antigen Stability, Immune Evasion and High production cost. Study of structure function relationship is a crucial part of the vaccine development.
Keywords: Protein Engineering, Antigens, Recombinant DNA Technology, Epitope Mapping, Immune Evasion.
Synergistic Anti-Migration Effects of Garcinia cowa and Doxorubicin in T47D Breast Cancer Cells: A Scratch Assay Analysis
Authors: Ifora Ifora , Hamidi Dachriyanus , Susanti Meri , Wahyuni Fatma Sri 
Published: February 2025

Objective: Breast cancer metastasis is a major cause of mortality, highlighting the need for effective anti-migratory therapies. This study investigated the synergistic anti-migratory effects of Garcinia cowa bark ethanol extract and doxorubicin on T47D breast cancer cells, aiming to explore its potential as a combination therapy to inhibit cancer cell migration
Methods: T47D cells were treated with Garcinia cowa bark ethanol extract (GCBEE) (130 µg/mL), doxorubicin (Dox) (0.026 µg/mL), and their combination. Cell migration was evaluated using the scratch assay, with scratch closure monitored at 0, 24, and 48 hours.
Results: The combination of GCBEE (130 µg/mL) and Dox (0.026 µg/mL) significantly inhibited T47D cell migration at both 24 and 48 hours, compared to the individual treatments of DOx (0.026 µg/mL) alone and GCBEE (130 µg/mL) alone.
Conclusions: The combination of Garcinia cowa ehtanol extract and doxorubicin demonstrates synergistic anti-migratory effects on T47D breast cancer cells, suggesting its potential as an adjuvant therapy to enhance the efficacy of doxorubicin in preventing metastasis.
Keywords: Garcinia cowa, doxorubicin, T47D cells, anti-migration, scratch assay, combination therapy.
Peran Motivasi Memasuki dunia Kerja dalam memediasi pengaruh Pengalaman Praktik Kerja Industri dan Locus of Control Internal terhadap Kesiapan Kerja Siswa
Authors: Armiati Armiati , Zahmelinda Septia , Hidayat M Topit 
Published: February 2025

This study aims to determine the effect of internship experience, internal locus of control, and motivation as a mediating variable on the work readiness of SMKN 2 Pariaman students. This type of research is causative. The research population was all class students of SMKN 2 Pariaman and the determination of the number of samples using the slovin formula was 153 samples. The sampling technique used proportional random sampling technique. The data used is the type of primary data obtained through the distribution of questionnaires to students. The analytical method used is path analysis using SPSS.The results showed that internship experience did not significantly affect the motivation of SMKN 2 Pariaman students, internal locus of control had a significant effect on the motivation, internship experience had a significant effect on students' work readiness, internal locus of control has a significant effect on student work readiness, motivation does not significantly affect student work readiness, industrial work experience does not significantly affect student work readiness through motivation as a mediating variable, internal locus of control has no significant effect on student work readiness as a mediating variable.