bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Highly Stereoselective C—C Bond Formation by Rhodium‐Catalyzed Tandem Ylide Formation/[2,3]‐Sigmatropic Rearrangement Between Donor/Acceptor Carbenoids and Chiral Allylic Alcohols.
Authors: Li Zhanjie , Parr Brendan T. , Davies Huw M. L. 
Published: December 2012

AbstractTwo vicinal stereogenic centers are generated in the title reaction with excellent enantioselectivity.
ChemInform Abstract: Enantioselective Synthesis of anti‐ and syn‐Homopropargyl Alcohols via Chiral Broensted Acid Catalyzed Asymmetric Allenylboration Reactions.
Authors: Chen Ming , Roush William R. 
Published: December 2012

AbstractThe chiral BINOL‐derived phosphate‐catalyzed addition of chiral allenic boronates towards aromatic and aliphatic aldehydes provides access towards anti‐ (IV), (VI) and syn‐homopropargyl alcohols (III) in good yields and high stereoselectivities, although aliphatic aldehydes provide the syn‐homopropargylic alcohols (VII) in low diastereoselectivity.
ChemInform Abstract: Rh‐Catalyzed Intermolecular Reactions of Cyclic α‐Diazocarbonyl Compounds with Selectivity over Tertiary C—H Bond Migration.
Authors: DeAngelis Andrew , Dmitrenko Olga , Fox Joseph M. 
Published: December 2012

AbstractSuitable reaction conditions are presented for the Rh‐catalyzed intermolecular reaction of cyclic α‐diazocarbonyl compounds (I), (XII) and (XX) with olefins, alkynes and O‐, N‐, S‐nucleophiles.
ChemInform Abstract: Synthesis of Phosphodiesterase IVb Inhibitors. Part 2. Stereoselective Synthesis of Hexahydro‐3H‐pyrrolo[1,2‐c]imidazol‐3‐one and Tetrahydro‐1H‐pyrrolo[1,2‐c][1,3]oxazol‐3‐one Derivatives.
Authors: Zhmurov P. A. , Tabolin A. A. , Sukhorukov A. Yu. , Lesiv A. V. , Klenov M. S. , Khomutova Yu. A. , Ioffe S. L. , Tartakovsky V. A. 
Published: December 2012

AbstractStarting from the known nitrone (I), the highly potent phosphodiesterase IVb inhibitors (VII) and (X) are stereoselectively synthesized in an overall yield of 22% and 18%, respectively.
ChemInform Abstract: Nonmetathetic Activity of Ruthenium Alkylidene Complexes: 1,4‐Hydrovinylative Cyclization of Multiynes with Ethylene.
Authors: Yun Sang Young , Wang Kung‐Pern , Kim Mansuk , Lee Daesung 
Published: December 2012

AbstractGrubbs′ second generation catalyst efficiently catalyzes the 1,4‐hydrovinylative cyclization of tetraynes (I), (VI) and triynes (VIII) under an ethylene atmosphere.
ChemInform Abstract: C—H Bond Functionalization via Hydride Transfer: Formation of α‐Arylated Piperidines and 1,2,3,4‐Tetrahydroisoquinolines via Stereoselective Intramolecular Amination of Benzylic C—H Bonds.
Authors: Vadola Paul A. , Carrera Ignacio , Sames Dalibor 
Published: December 2012

AbstractTreatment of aldehydes of type (I), (IV), (VI), and (IX) with Tos‐NH2 leads to imines which in the presence of BF3·OEt2 undergo cyclization to α‐arylated piperidines and tetrahydroisoquinolines.
ChemInform Abstract: Ring Transformations of β‐Lactam‐Condensed 1,3‐Benzothiazines to Isoquinoline and Thiazole Derivatives by Sulfur Extrusion and Addition Sequences.
Authors: Fodor Lajos , Csomos Peter , Csampai Antal , Sohar Pal 
Published: December 2012

AbstractThe ring transformation of dichloro β‐lactams (I) in the presence of sodium methoxide is investigated.
ChemInform Abstract: Photoinduced Addition and Addition—Elimination Reactions of Perfluoroalkyl Iodides to Electron‐Deficient Olefins.
Authors: Yajima Tomoko , Jahan Ishrat , Tonoi Takayuki , Shinmen Manami , Nishikawa Aya , Yamaguchi Kanako , Sekine Izumi , Nagano Hajime 
Published: December 2012

AbstractPhotoinduced radical perfluoroalkylation of various simple electron‐deficient olefins is achieved in the presence of an aqueous Na2S2O3 solution.
ChemInform Abstract: Transition Metal Free Transfer Hydrogenation of Ketones Promoted by 1,3‐Diarylimidazolium Salts and KOH.
Authors: Ikhile Monisola Itohan , Nyamori Vincent Onserio , Bala Muhammad Dabai 
Published: December 2012

AbstractIMD is found to be most efficient salt for the process which utilizes mild aerobic conditions compared to the inert atmosphere required for metal‐based systems.
ChemInform Abstract: An Expedient Route for the Reduction of Carboxylic Acids to Alcohols Employing 1‐Propanephosphonic Acid Cyclic Anhydride as Acid Activator.
Authors: Nagendra G. , Madhu C. , Vishwanatha T. M. , Sureshbabu Vommina V. 
Published: December 2012

AbstractA simple protocol presented for the reduction of carboxylic acids as well as amino acids and peptides to the corresponding alcohols under mild conditions.
ChemInform Abstract: Copper‐Catalyzed Conversion of Aryl and Heteroaryl Bromides into the Corresponding Chlorides.
Authors: Feng Xiujuan , Qu Yiping , Han Yanlei , Yu Xiaoqiang , Bao Ming , Yamamoto Yoshinori 
Published: December 2012

AbstractThe reaction is conducted under mild conditions using a very inexpensive chlorine source.
ChemInform Abstract: A Protocol for Accessing the β‐Azidation of α,β‐Unsaturated Carboxylic Acids.
Authors: Angelini Tommaso , Bonollo Simona , Lanari Daniela , Pizzo Ferdinando , Vaccaro Luigi 
Published: December 2012

AbstractThe new, efficient, and recoverable bifunctional supported ammonium fluoride PAS selectively catalyzes the direct and solvent‐free β‐azidation of the title carboxylic acids without the need to protect/deprotect the carboxylic functionality.
ChemInform Abstract: Kumada—Tamao—Corriu Coupling of Heteroaromatic Chlorides and Aryl Ethers Catalyzed by (IPr)Ni(allyl)Cl.
Authors: Iglesias Maria Jose , Prieto Auxiliadora , Nicasio M. Carmen 
Published: December 2012

AbstractThe title reaction allows an efficient access to a number of biaryls and heterobiaryls.
ChemInform Abstract: Preparation of α,β‐Unsaturated Esters and Amides via External CO‐Free Palladium‐Catalyzed Carbonylation of Alkenyl Tosylates.
Authors: Ueda Tsuyoshi , Konishi Hideyuki , Manabe Kei 
Published: December 2012

AbstractThe tosylate substrates react with phenyl formate (II) to give α,β‐unsaturated esters directly.
ChemInform Abstract: Aluminum Triflate Catalyzed O‐Glycosidation: Temperature‐Switched Selective Ferrier Rearrangement or Direct Addition with Alcohols.
Authors: Williams D. Bradley G. , Simelane Sandile B. , Kinfe Henok H. 
Published: December 2012

AbstractThe reaction of benzyl protected glycal (I) with both aliphatic and aromatic alcohols in the presence of Al(O‐Tf)3 proceeds either via addition or via Ferrier rearrangement depending on the reaction temperature.
ChemInform Abstract: Heteropolyacid‐Catalyzed Direct Deoxygenation of Propargyl and Allyl Alcohols.
Authors: Egi Masahiro , Kawai Takuya , Umemura Megumi , Akai Shuji 
Published: December 2012

AbstractTreatment of propargyl and allyl alcohols with Et3SiH and H3[PW12O40] provides a mild and efficient approach to various alkynes and trisubstituted alkenes.
ChemInform Abstract: Pd/Light‐Accelerated Atom‐Transfer Carbonylation of Alkyl Iodides: Applications in Multicomponent Coupling Processes Leading to Functionalized Carboxylic Acid Derivatives.
Authors: Fusano Akira , Sumino Shuhei , Nishitani Satoshi , Inouye Takaya , Morimoto Keisuke , Fukuyama Takahide , Ryu Ilhyong 
Published: December 2012

AbstractThree‐ and four‐component reactions towards functionalized esters, lactones and lactames are developed based on palladium/light induced, radical carbonylation reactions.
ChemInform Abstract: Single‐Step Thioetherification by Indium‐Catalyzed Reductive Coupling of Carboxylic Acids with Thiols.
Authors: Sakai Norio , Miyazaki Takahiro , Sakamoto Tomohiro , Yatsuda Takuma , Moriya Toshimitsu , Ikeda Reiko , Konakahara Takeo 
Published: December 2012

AbstractIt provides a new method to prepare a wide range of thioethers.
ChemInform Abstract: Rhodium‐Catalyzed Carbonylation of Cyclopropyl Substituted Propargyl Esters: A Tandem 1,3‐Acyloxy Migration [5 + 1] Cycloaddition.
Authors: Shu Dongxu , Li Xiaoxun , Zhang Min , Robichaux Patrick J. , Guzei Ilia A. , Tang Weiping 
Published: December 2012

AbstractThe title reaction allows an efficient access to highly substituted cyclohexenones.
ChemInform Abstract: S‐Benzyl Isothiouronium Chloride as a Recoverable Organocatalyst for the Reduction of Conjugated Nitroalkenes with Hantzsch Ester.
Authors: Nguyen Quynh Pham Bao , Kim Jae Nyoung , Kim Taek Hyeon 
Published: December 2012

AbstractThe reduction of unsaturated nitroalkanes into nitroalkanes using a combination of Hantzsch ester and S‐benzyl isothiouronium chloride as organic catalyst system is reported.
ChemInform Abstract: Samarium Diiodide Promoted Tandem β‐Elimination and Cross‐Pinacol Coupling: A New Access to 1‐Vinyl‐1,2‐diols with Two Adjacent Quaternary Carbon Centers.
Authors: Zhao Yun‐Hui , Ma Ru‐Lin , Sun Xing‐Wen , Lin Guo‐Qiang 
Published: December 2012

Abstract1,3‐Dioxolane substrates rearrange in the presence of excess SmI2 to afford novel 1,2‐diol structures as highly functionalized skeletons for natural product syntheses.
ChemInform Abstract: Metal‐Free N—H Insertions of Donor/Acceptor Carbenes.
Authors: Hansen Stephanie R. , Spangler Jillian E. , Hansen Joern H. , Davies Huw M. L. 
Published: December 2012

AbstractThe thermal decomposition of aryldiazoacetates generates carbenes, which directly undergo the C—H insertion reactions with a wide range of primary and secondary alkyl‐ and aryl/heteroarylamines to give α‐arylamino esters in good yields.
ChemInform Abstract: A Straightforward and General Access to α‐Phthalimido‐α′‐substituted Propan‐2‐ones.
Authors: Pace Vittorio , Holzer Wolfgang 
Published: December 2012

AbstractRegioselective ring opening of starting compound (I) with a variety of nucleophiles produces propan‐2‐ol derivatives which are readily oxidized to the corresponding ketones in excellent yields.
ChemInform Abstract: TBD‐Catalyzed α‐Sulfenylation of Cyclic Ketones: Desymmetrization of 4‐Substituted Cyclohexanones.
Authors: Poladura Belen , Martinez‐Castaneda Angel , Rodriguez‐Solla Humberto , Concellon Carmen , del Amo Vicente 
Published: December 2012

AbstractA simple and efficient protocol for the α‐sulfenylation of cyclic ketones is developed.
ChemInform Abstract: Transition‐Metal‐Free α‐Arylation of β‐Keto Amides via an Interrupted Insertion Reaction of Arynes.
Authors: Mohanan Kishor , Coquerel Yoann , Rodriguez Jean 
Published: December 2012

AbstractBoth cyclic and acyclic β‐keto amides undergo the title reaction to give the corresponding α‐phenyl‐ or α‐(2‐naphthyl)‐substituted products.
ChemInform Abstract: A One‐Pot Synthesis of 1,4‐Naphthoquinone‐2,3‐bis‐sulfides Catalyzed by a Commercial Laccase.
Authors: Wellington Kevin W. , Bokako Refiloe , Raseroka Nelly , Steenkamp Paul 
Published: December 2012

AbstractAn oxidative C—S bond formation with alkyl and aryl thiols (II) and (IV) is achieved under mild conditions from both the naphthohydroquinone carboxylic acid (I) and the naphthohydroquinone (VI), enabling direct access to naphthoquinone (bis)sulfides such as (III) and (V).
ChemInform Abstract: Base‐ and Metal‐Free C—H Direct Arylations of Naphthalene and Other Unbiased Arenes with Diaryliodonium Salts.
Authors: Castro Susana , Fernandez Juan J. , Vicente Ruben , Fananas Francisco J. , Rodriguez Felix 
Published: December 2012

AbstractThe arylation of naphthalene with diaryliodonium triflate (I) proceeds readily under microwave irradiation to afford 1‐arylnaphthalene (III) as main product.
ChemInform Abstract: Pd‐Catalyzed Double C—H Bond Activation of Diaryl Ketones for the Synthesis of Fluorenones.
Authors: Gandeepan Parthasarathy , Hung Chen‐Hsun , Cheng Chien‐Hong 
Published: December 2012

AbstractThe palladium‐catalyzed oxidative cyclization of benzophenones (I) leads to desired fluorenones (II) in good yields.
ChemInform Abstract: Visible Light Induced Intermolecular [2 + 2]‐Cycloaddition Reactions of 3‐Ylideneoxindoles Through Energy Transfer Pathway.
Authors: Zou You‐Quan , Duan Shu‐Wen , Meng Xiang‐Gao , Hu Xiao‐Qiang , Gao Shuang , Chen Jia‐Rong , Xiao Wen‐Jing 
Published: December 2012

AbstractTitle reaction provides access towards structurally constraint spirooxindoles bearing four contiguous stereocenters in excellent diastereoselectivity.
ChemInform Abstract: Benzyl‐Type Cation Initiated Nucleophilic Substitution on Furan and Thiophene by Using α‐EWG Ketene S,S‐Acetals as Nucleophiles.
Authors: Sun Shaoguang , Liu Jun , Liu Qun , Wang Mang 
Published: December 2012

AbstractNovel Lewis acid catalyzed reactions of furan and thiophene derivatives including aldehydes and Baylis—Hillman adducts with ketene S,S‐acetals are investigated.
ChemInform Abstract: Stereospecific Synthesis of endo‐endo‐3,7‐Dioxabicyclo[3.3.0]octane Lignans Using 1,6‐Bis(dipropylboryl)‐2,4‐hexadiene.
Authors: Anfimov A. N. , Erdyakov S. Yu. , Gurskii M. E. , Bubnov Yu. N. 
Published: December 2012

AbstractStereospecific intramolecular cyclization of known unsaturated diols (I) is achieved by ozonolysis, whereas other methods such as iodocyclization fail.
ChemInform Abstract: Synthesis of C1‐Substituted Oxabenzonorbornadienes.
Authors: Haner Jamie , Jack Kelsey , Menard Michelle L. , Howell Jennifer , Nagireddy Jaipal , Raheem Mohammed Abdul , Tam William 
Published: December 2012

AbstractThe title compounds, which are of interest as precursors of highly substituted ring systems, can be directly prepared by Diels—Alder reaction of benzyne with 2‐substituted furans.
ChemInform Abstract: Visible Light‐Induced Synthesis of 3,4‐Diarylthiophenes from 3,4‐Diaryl‐2,5‐dihydrothiophenes.
Authors: Chen Yu‐Zhe , Wang Deng‐Hui , Chen Bin , Zhong Jian‐Ji , Tung Chen‐Ho , Wu Li‐Zhu 
Published: December 2012

AbstractIt provides a facile method to prepare 3,4‐diarylthiophenes.
ChemInform Abstract: Iodine‐Catalyzed Highly Efficient Synthesis of 3‐Alkylated/3‐Alkenylated Indoles from 1,3‐Dicarbonyl Compounds.
Authors: Singh Neetu , Singh Krishna Nand 
Published: December 2012

AbstractThe reaction leads to the desired products if dimedone (II) is used as dicarbonyl unit.
ChemInform Abstract: One‐Pot Synthesis of 1H‐Benzimidazole Derivatives Using Thiamine Hydrochloride as a Reusable Organocatalyst.
Authors: Lei Min , Ma Lei , Hu Lihong 
Published: December 2012

AbstractThiamine hydrochloride is shown to be an efficient catalyst for the synthesis of benzimidazole derivatives of type (III) or (V) from o‐phenylendiamine and aromatic aldehydes.
ChemInform Abstract: Microwave‐Assisted Hantzsch Thiazole Synthesis of N‐Phenyl‐4‐(6‐phenylimidazo[2,1‐b]thiazol‐5‐yl)thiazol‐2‐amines from the Reaction of 2‐Chloro‐1‐(6‐phenylimidazo[2,1‐b]thiazol‐5‐yl)ethanones and Thioureas.
Authors: Kamila Sukanta , Mendoza Kimberly , Biehl Edward R. 
Published: December 2012

AbstractThe biologically important title structures (III) can be prepared in an easy manner with good to excellent yields.
ChemInform Abstract: Indium‐Mediated Regioselective Mono‐Allylation of 1,5‐Dicarbonyl Compounds and Dehydrative Cyclization to 2,3‐Dihydro‐4H‐pyran‐4‐ones and 3,4‐Dihydro‐2H‐[1,4]oxazines.
Authors: Kim Sung Hwan , Lee Sangku , Kim Se Hee , Lim Jin Woo , Kim Jae Nyoung 
Published: December 2012

AbstractIn the case of intermediates (VIIb) and (XIb), unexpected bicyclic products (IX) and (XIII) are obtained.
ChemInform Abstract: Synthesis of (5S*,4aS*,7aS*)‐5‐Hydroxyhexahydrocyclopenta[c]pyran‐3(1H)‐one.
Authors: Lozanova A. V. , Chizhov A. O. , Veselovsky V. V. 
Published: December 2012

AbstractTitle compound (VII) is synthesized as potential isoprostane building block.
ChemInform Abstract: Synthesis of Substituted Quinolines from N‐Aryl‐N‐(2‐alkynyl)toluenesulfonamides via FeCl3‐Mediated Intramolecular Cyclization and Concomitant Detosylation.
Authors: Roy B. , Ansary Inul , Samanta Srikanta , Majumdar K. C. 
Published: December 2012

AbstractOptimized conditions afford the target compounds via a 6‐endo‐dig cyclization/detosylation sequence and are suitable for the access to a diverse range of quinoline structures from simple starting materials.
ChemInform Abstract: Reductive Nitro‐Mannich Route for the Synthesis of 1,2‐Diamine Containing Indolines and Tetrahydroquinolines.
Authors: Anderson James C. , Noble Adam , Tocher Derek A. 
Published: December 2012

AbstractA convenient and highly stereoselective method to prepare 3‐aminotetrahydroquinolines and 2‐aminomethylene indolines starting from nitrostyrenes of type (I) is reported.
ChemInform Abstract: Synthesis of C1‐Indol‐3‐yl‐Substituted Tetrahydroisoquinoline Derivatives via a Pictet—Spengler Approach.
Authors: Larsson Rikard , Blanco Narda , Johansson Martin , Sterner Olov 
Published: December 2012

AbstractThe condensation of L‐DOPA derivative (I) with aldehydes (II) provides a diastereomeric mixture of tetrahydroquinolines.
ChemInform Abstract: Mannich Reaction in the Synthesis of N,S‐Containing Heterocycles. Part 14. Unexpected Formation of Thiazolo[3,2‐a]pyridines in the Aminoalkylation of N‐Methylmorpholinium 4‐Aryl‐3‐cyano‐6‐oxo‐1,4,5,6‐tetrahydropyridine‐2‐thiolates by Isobutyraldehyde and Primary Amines.
Authors: Dotsenko V. V. , Krivokolysko S. G. 
Published: December 2012

AbstractTitle compounds (IV) are synthesized through a three‐component condensation starting from thiolates (I).
ChemInform Abstract: Novel Synthesis of Functionalized Indolizine Derivatives from Huisgen′s Zwitterions and 1‐Methylimidazole/Dichloroketene Adduct.
Authors: Yavari Issa , Hosseinpour Reza , Pashazadeh Ramin , Skoulika Stavroula 
Published: December 2012

AbstractThe process involves the in situ formation of zwitterionic intermediates from pyridines or quinolines and dimethyl acetylene dicarboxylate.
ChemInform Abstract: Copper(II)/Iron(III) Co‐Catalyzed Intermolecular Diamination of Alkynes: Facile Synthesis of Imidazopyridines.
Authors: Zeng Jing , Tan Yu Jia , Leow Min Li , Liu Xue‐Wei 
Published: December 2012

AbstractThe reaction proceeds with high regioselectivity and imidazoisoquinolines are also available.
ChemInform Abstract: New Three‐Component Reaction of Perimidines with Sodium Azide and Sodium Nitrile in Polyphosphoric Acid.
Authors: Lyakhovnenko A. S. , Aksenov A. V. , Aksenov N. A. , Goncharov V. I. , Aksenova I. V. 
Published: December 2012

AbstractAll products are purified by recrystallization.
ChemInform Abstract: Design and Synthesis of a Novel Pyrrolidinyl Pyrido Pyrimidinone Derivative as a Potent Inhibitor of PI3Kα and mTOR.
Authors: Le Phuong T. , et al. et al. 
Published: December 2012

AbstractLead optimization efforts that employed structure‐based drug design and physicochemical property based refinement lead to the discovery of title compound (XIII) which exhibits potent activity against PI3Kα and mTOR, good kinase selectivity, and robust ADMET properties as well as good oral bioavailability.
ChemInform Abstract: Pd‐Catalyzed Amination of 6‐Halo‐2‐cyclopropyl‐3‐(pyridyl‐3‐ylmethyl)quinazolin‐4(3H)‐one.
Authors: Garlapati Ramesh , Pottabathini Narender , Gurram Venkateshwarlu , Chaudhary Avinash B. , Chunduri Venkata Rao , Patro Balaram 
Published: December 2012

AbstractThe halogenated substrates (I) and (IV) are used for amination in order to prepare highly functionalized derivatives of the pharmaceutically important skeleton.
ChemInform Abstract: New Tricyclic Compounds with Pyrimido[4,5‐d]pyrimidine Fragment, the 7,8‐Dihydro‐1H‐pyrimido[4,5,6‐de]quinazoline Derivatives.
Authors: Dorokhov V. A. , Voronkova V. A. , Komkov A. V. , Shashkov A. S. 
Published: December 2012

AbstractNovel fused heterocycles (VI) are obtained by the sequential reaction of 2‐diaminomethylidenedimedone with aryl isocyanates.
ChemInform Abstract: An Efficient One‐Pot Multicomponent Synthesis of 2,3‐Dihydro‐3‐alkyl/aryl‐2‐thioxoquinazolin‐4(1H)‐ones under Solvent‐Free Conditions.
Authors: Devi Nepram Sushuma , Singh Sarangthem Joychandra , Singh Okram Mukherjee 
Published: December 2012

AbstractThe procedure is highly efficient in the case of primary aliphatic amines and no catalyst is necessary.
ChemInform Abstract: Novel Spiroderivatives of Isothiourea of the 1,3‐Thiazine Series as Promising Neuroprotectors.
Authors: Proshin A. N. , Serkov I. V. , Petrova L. N. , Bachurin S. O. 
Published: December 2012

AbstractA synthetic route to the hitherto unknown 2‐aminospirothiazines (III) is developed.
ChemInform Abstract: Modular Functionalization of Allenes to Aminated Stereotriads.
Authors: Adams Christopher S. , Boralsky Luke A. , Guzei Ilia A. , Schomaker Jennifer M. 
Published: December 2012

AbstractRhodium‐catalyzed cyclization of allenic sulfamate (I) provides access towards a strained bicyclic methylene aziridine intermediate, which undergoes aziridine ring opening on reaction with various nucleophiles to afford cyclic sulfamates (III).
ChemInform Abstract: Conformationally Restricted Peptide Mimetics by Ring‐Closing Olefin Metathesis.
Authors: Wakchaure Satish , Einsiedel Juergen , Waibel Reiner , Gmeiner Peter 
Published: December 2012

AbstractThe RCM‐based synthetic strategy to access cyclic peptide mimetics is extended to 10‐membered lactams of type (II).
ChemInform Abstract: Tricyclic Pyrazoles: An Efficient Approach to Cannabinoid Analogues with a Tricyclic Framework Incorporating the Pyrrole and Pyrazole Moieties.
Authors: Pinna Giansalvo , Pinna Gerard A. , Chelucci Giorgio , Baldino Salvatore 
Published: December 2012

AbstractThe synthesis of cyclic analogues (VIII) and (IX) of the potent and selective CB1 antagonist rimonabant is developed.
ChemInform Abstract: Synthesis of Chalcones Derived from (+)‐ and (‐)‐Usnic Acids.
Authors: Sokolov D. N. , Luzina O. A. , Polovinka M. P. , Salakhutdinov N. F. , Tolstikov G. A. 
Published: December 2012

AbstractDifferent pathways to obtain chalcones from usnic acid derivative (I) are studied.
ChemInform Abstract: Epitaxially Stabilized EuMoO3: A New Itinerant Ferromagnet.
Authors: Kozuka Yusuke , et al. et al. 
Published: December 2012

AbstractAn epitaxially stabilized new perovskite compound, EuIIMoIVO3 is prepared as a thin film by pulsed laser deposition using perovskite substrates.
The risk of developing invasive breast cancer in Hispanic women
Authors: Banegas Matthew P. , Leng Mei , Graubard Barry I. , Morales Leo S. 
Published: December 2012

AbstractBACKGROUND:Current evidence on breast cancer among US Hispanic women indicates a significant public health threat, although few studies have assessed the heterogeneity in breast cancer risk among Hispanics of different origin.METHODS:The 2000 and 2005 National Health Interview Survey Cancer Control Modules were used to examine the Breast Cancer Risk Assessment Tool (BCRAT) 5‐year risk and lifetime risk of invasive breast cancer among Mexican/Mexican American, Puerto Rican, Cuban/Cuban American, Dominican (Republic), Central/South American, Other Hispanic, and non‐Hispanic white (NHW) women ages 35 to 84 years. Multiple linear regression models were used to compare the BCRAT 5‐year and lifetime breast cancer risk between 1) Hispanics and NHWs and 2) Hispanic subgroups.RESULTS:Hispanic women had significantly lower mean BCRAT 5‐year and lifetime breast cancer risk compared with NHW women (P < .001). Among Hispanic subgroups, Cuban/Cuban Americans had a higher BCRAT 5‐year risk (P < .05), whereas Dominicans had a higher lifetime risk (P < .001) compared with Mexican/Mexican Americans. Approximately 2.6% of Hispanic women were at high risk for breast cancer (BCRAT 5‐year risk ≥1.67%), ranging from 1% of Central/South Americans to 3.7% of Puerto Ricans; few Hispanics (0.2%) had a lifetime risk ≥20%.CONCLUSIONS:The current findings indicate that Hispanic women have a significantly lower risk of breast cancer compared with NHW women, although the risk according to BCRAT differed significantly between specific Hispanic subgroups. We provide estimates of the number of US Hispanic women from six subgroups who may be eligible for prophylactic breast cancer chemoprevention. The authors concluded that future studies should further investigate the heterogeneity in breast cancer risk and risk factors between Hispanic women of different origins. Cancer 2013. © 2012 American Cancer Society.