bluuebunny/crossref_metadata_2025_split huggingface dataset:
Progressive Originalism and the New Canon Wars
Authors: Khan Almas 
Published: August 2024

Abstract
This essay responds to Geoffrey Kirsch’s review essay “What’s Past is Prologue: Democracy in the Age of Originalism” by evaluating how the three texts Kirsch reviews—Kermit Roosevelt, III’s The Nation That Never Was: Reconstructing America’s Story (2022), Cass R. Sunstein’s How to Interpret the Constitution (2023), and D. Berton Emerson and Gregory Laski’s edited collection Democracies in America: Keywords for the Nineteenth Century and Today (2023)—engage with progressive originalism. Drawing inspiration from civil rights activists including Frederick Douglass, progressive originalists seek to recast an ostensibly conservative method of constitutional interpretation grounded in what the “founding fathers” or a historical public thought or intended. Roosevelt’s and Sunstein’s books reveal the potential and limits of both progressive originalism and insular disciplinary conversations about constitutional interpretation. Contrastingly, the multidisciplinary Democracies in America has a more expansive conception of whose voices should matter when interpreting the Constitution through a progressive originalist lens. A comparative analysis of the three books also demonstrates the value of literature and literary historians in an age characterized by the ascendancy of historical approaches to constitutional interpretation and a revival of the “canon wars.”
Preoperative Patient Guidance and Education in Aesthetic Breast Plastic Surgery: A Novel Proposed Application of Artificial Intelligence Large Language Models
Authors: Abi-Rafeh Jad , Bassiri-Tehrani Brian , Kazan Roy , Furnas Heather , Hammond Dennis , Adams William P , Nahai Foad 
Published: August 2024

Abstract

Background
At a time when Internet and social media use is omnipresent among patients in their self-directed research about their medical or surgical needs, artificial intelligence (AI) large language models (LLMs) are on track to represent hallmark resources in this context.

Objectives
The authors aim to explore and assess the performance of a novel AI LLM in answering questions posed by simulated patients interested in aesthetic breast plastic surgery procedures.

Methods
A publicly available AI LLM was queried using simulated interactions from the perspective of patients interested in breast augmentation, mastopexy, and breast reduction. Questions posed were standardized and categorized under aesthetic needs inquiries and awareness of appropriate procedures; patient candidacy and indications; procedure safety and risks; procedure information, steps, and techniques; patient assessment; preparation for surgery; postprocedure instructions and recovery; and procedure cost and surgeon recommendations. Using standardized Likert scales ranging from 1 to 10, 4 expert breast plastic surgeons evaluated responses provided by AI. A postparticipation survey assessed expert evaluators' experience with LLM technology, perceived utility, and limitations.

Results
The overall performance across all question categories, assessment criteria, and procedures examined was 7.3/10 ± 0.5. Overall accuracy of information shared was scored at 7.1/10 ± 0.5; comprehensiveness at 7.0/10 ± 0.6; objectivity at 7.5/10 ± 0.4; safety at 7.5/10 ± 0.4; communication clarity at 7.3/10 ± 0.2; and acknowledgment of limitations at 7.7/10 ± 0.2. With regards to performance on procedures examined, the model's overall score was 7.0/10 ± 0.8 for breast augmentation; 7.6/10 ± 0.5 for mastopexy; and 7.4/10 ± 0.5 for breast reduction. The score on breast implant–specific knowledge was 6.7/10 ± 0.6.

Conclusions
Albeit not without limitations, AI LLMs represent promising resources for patient guidance and patient education. The technology's machine learning capabilities may explain its improved performance efficiency.

Level of Evidence: 4
Localised waste reduction networks, global destruction networks and the circular economy
Authors: Bryson John R , Herod Andrew , Johns Jennifer , Vanchan Vida 
Published: August 2024

Abstract
Creating a circular economy (CE) is considered central to solving problems like climate change and resource depletion. In this context, the concept of global destruction networks was developed to better theorise using waste in new production. However, CE advocates also seek to avoid waste production by extending products’ lives. These efforts occur within what we term waste reduction networks. Examining how these two sets of networks intersect allows a fuller understanding of the CE’s emergent geographies. We analyse 17 European and US clothing firms focussed on value creation through waste minimisation to illustrate our argument.
Therapeutic targets in membranous nephropathy: plasma cells and complement
Authors: Tomas Nicola M 
Published: August 2024

ABSTRACT
Membranous nephropathy (MN) is an antibody-mediated autoimmune disease and the most common cause of nephrotic syndrome in adults. The discovery of phospholipase A2 receptor 1 (PLA2R1) as the first target antigen in patients with MN 15 years ago has led to a paradigm shift in the pathobiological understanding of this disease. Autoantibodies against PLA2R1 as well as thrombospondin type-1 domain-containing 7A, the second identified antigen in adults, were shown to be disease-causing and act through local activation of the complement system, primarily via the classical and lectin pathways. These findings indicate that both plasma cells, the main source of antibodies and autoantibodies, as well as the complement system, the main pathogenic effector mechanism in MN, are rational and pathogenesis-based treatment targets in MN. This review summarizes pathomechanistic and clinical evidence for and against plasma cell– and complement-targeted treatments in MN.
A fiery heart: case report of perimyocarditis in a patient with eosinophilic granulomatosis with polyangiitis
Authors: Park Dae Yong , Planek Maria Isabel , Mohammed Abdul Khayyam , Nanna Michael G , Alyousef Tareq 
Published: August 2024

Abstract

Background
Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare disease caused by small- to medium-sized vessel vasculitis which can also impact the heart. Because of its rarity and diverse clinical manifestations, diagnosis can be challenging. Here, we present a unique case of EGPA causing perimyocarditis in a young female patient.

Case summary
A 37-year-old woman with hypertension, asthma, and sickle cell trait presented with palpitations, dyspnoea, and sharp chest pain. White blood cell was elevated to 16 300/μL with peripheral eosinophilia at 5216/μL. Electrocardiogram revealed sinus tachycardia with frequent non-sustained ventricular tachycardia. Echocardiogram showed an ejection fraction of 20–25% with severe diffuse hypokinesis and dilated cardiac chambers. Coronary angiogram was normal. Cardiac magnetic resonance imaging revealed focal subendocardial late gadolinium enhancement (LGE) of the septum and subepicardial LGE of the basal anterolateral wall of the left ventricle. Further work-up showed elevated Immunoglobulin E level, left antrochoanal polyp, and ground glass opacities in the left upper lobe. Endomyocardial biopsy showed interstitial infiltrates of eosinophils with sporadic necrosis, confirming the diagnosis of EGPA perimyocarditis. The patient was treated with prednisone, colchicine, and guideline-directed medical therapy.

Discussion
This case report describes an unusual cause of perimyocarditis. Keeping a broad differential is important as diagnosis is challenging, and cardiac involvement in EGPA is associated with higher morbidity and mortality. Recognizing the typical manifestations of EGPA, implementing multidisciplinary approach, and promptly initiating appropriate treatment are crucial for the optimal management of EGPA perimyocarditis.
The optimal degree of core temperature for hypothermic circulatory arrest in complex aortic arch surgery: results from 1310 patients
Authors: Zhang Kai , Zhou Chenyu , Gao Shiqi , Ji Yumeng , Qiu Jiawei , Cao Fangfang , Qiu Juntao , Yu Cuntao 
Published: August 2024

Abstract

OBJECTIVES
The optimal core temperature for hypothermic circulatory arrest during aortic arch surgery remains contentious. This study aims to evaluate patient outcomes under various temperatures within a large single-centre cohort.

METHODS
Between 2010 and 2018, patients diagnosed with type A aortic dissection underwent total arch replacement at Fuwai Hospital were enrolled. They were categorized into 4 groups: deep hypothermia group, low-moderate hypothermia group, high-moderate hypothermia group and mild hypothermia group. Clinical data were analysed to ascertain differences between the groups.

RESULTS
A total of 1310 patients were included in this cohort. Operative mortality stood at 6.9% (90/1310), with a higher incidence observed in the deep hypothermia group [29 (12.9%); 35 (6.9%); 21 (4.8%); 5 (3.4%); all adjusted P &lt; 0.05]. Overall 10-year survival was 80.3%. Long-term outcomes did not significantly differ among the groups. Multivariable logistic analysis revealed a protective effect of higher core temperature on operative mortality (odds ratio 0.848, 95% confidence interval 0.766–0.939; P = 0.001). High-moderate hypothermia emerged as an independent protective factor for operative mortality (odds ratio 0.303, 95% confidence interval 0.126–0.727; P = 0.007). Multivariable Cox analysis did not detect an effect of hypothermic circulatory arrest on long-term survival (all P &gt; 0.05).

CONCLUSIONS
High-moderate hypothermia (24.1–28°C) offers the most effective protection against surgical mortality and is therefore recommended. Different hypothermic circulatory arrest temperatures do not influence long-term survival or quality of life.
Molecular phylogeny of old-world Dryopoidea beetles (Coleoptera: Polyphaga: Elateriformia) based on ultraconserved elements of DNA sequence data from Japanese taxa
Authors: Hayashi Masakazu , Kobayashi Takuya , Yoshitomi Hiroyuki , Sota Teiji 
Published: August 2024

Abstract
The superfamily Dryopoidea is a diverse group of beetles with a mixture of aquatic, semiaquatic, and terrestrial life histories. These beetles exhibit remarkable morphological diversity, particularly in the larval stages, which is likely associated with their repeated adaptation to aquatic habitats. The phylogenetic relationships among Dryopoidea families and subfamilies are controversial, as phylogenetic analyses based on morphology have failed to propose robust and consistent hypotheses. However, recent molecular phylogenetic studies have provided better resolution for the interfamilial relationships and suggested the non-monophyly of a few families. In this study, we conducted phylogenetic analyses of Dryopoidea obtained in Japan along with other groups in the Elateriformia (Byrrhoidea, Dascilloidea, Buprestoidea, and Elateroidea) using sequence data from ultraconserved elements with the maximum-likelihood method and species-tree analysis based on a multispecies coalescent model. Our results show that Dryopoidea is a monophyletic group, not sister to Byrrhoidea. In Dryopoidea, Dryopidae is sister to all other groups, and Psephenidae and Ptilodactylidae are not monophyletic groups. In Psephenidae, Eubrianacinae has clearly diverged from the other subfamilies (Psepheninae, Psephenoidinae, and Eubriinae) and is closely related to Callirhipidae; in Ptilodactylidae, Cladotominae is related to Psephenidae (except Eubrianacinae) + Chelonariidae and separated from the other Ptilodactylidae subfamilies (Anchytarsinae and Ptilodactylinae). Although ML analyses indicated paraphyly of subfamilies in Limnichidae and Psephenidae (except Eubrianacinae), this was resolved in species tree analysis. Our results show that Eubrianacinae and Cladotominae are clearly distinct groups with different origins from other subfamilies of the respective families and can be separated as independent families.
Generalizable clinical note section identification with large language models
Authors: Zhou Weipeng , Miller Timothy A 
Published: August 2024

Abstract

Objectives
Clinical note section identification helps locate relevant information and could be beneficial for downstream tasks such as named entity recognition. However, the traditional supervised methods suffer from transferability issues. This study proposes a new framework for using large language models (LLMs) for section identification to overcome the limitations.

Materials and Methods
We framed section identification as question-answering and provided the section definitions in free-text. We evaluated multiple LLMs off-the-shelf without any training. We also fine-tune our LLMs to investigate how the size and the specificity of the fine-tuning dataset impacts model performance.

Results
GPT4 achieved the highest F1 score of 0.77. The best open-source model (Tulu2-70b) achieved 0.64 and is on par with GPT3.5 (ChatGPT). GPT4 is also found to obtain F1 scores greater than 0.9 for 9 out of the 27 (33%) section types and greater than 0.8 for 15 out of 27 (56%) section types. For our fine-tuned models, we found they plateaued with an increasing size of the general domain dataset. We also found that adding a reasonable amount of section identification examples is beneficial.

Discussion
These results indicate that GPT4 is nearly production-ready for section identification, and seemingly contains both knowledge of note structure and the ability to follow complex instructions, and the best current open-source LLM is catching up.

Conclusion
Our study shows that LLMs are promising for generalizable clinical note section identification. They have the potential to be further improved by adding section identification examples to the fine-tuning dataset.
Common consumer residual insecticides lack efficacy against insecticide-susceptible and resistant populations of the German cockroach (Blattodea: Ectobiidae)
Authors: Gordon Johnalyn M , Eva Marla J , Gaire Sudip , Appel Arthur G , DeVries Zachary C 
Published: August 2024

Abstract
The German cockroach, Blattella germanica (L.) (Blattodea: Ectobiidae), is a ubiquitous pest in affordable housing. They represent a major threat to human health due to their contribution of asthma-exacerbating allergens and the potential to transfer pathogenic microorganisms indoors. Despite well-documented pyrethroid resistance, pyrethroid-based broadcast residual insecticide products are often used by residents to control cockroaches in their homes. Additionally, there is little empirical independent testing of these products. Thus, it remains unclear how effective these commonly used do-it-yourself products are at controlling German cockroaches. This study represents a comprehensive examination of the efficacy of these products with direct, limited, and continuous exposure assays on a variety of common household surfaces on field populations of cockroaches with varying levels of pyrethroid resistance. While most products performed well when applied directly to test insects, mortality was substantially lower across all surfaces with limited exposure (30 min). In continuous exposure assays on a nonporous surface, products took at least 24 hr to cause 100% mortality in a field population, with some products taking up to 5 d to achieve 100% mortality. The findings of this study demonstrate a lack of residual efficacy from common pyrethroid-based consumer-use pesticides products. Given that it is not feasible to find and treat every cockroach in a home directly, the residuality of spray-based formulations is critical for products designed to control German cockroaches. Without residual efficacy, as shown in the consumer aerosol and spray products tested, we expect these products to add little to no value to cockroach control.
Transnational Human Rights Violations: Addressing the Evolution of Globalized Repression through National Human Rights Institutions
Authors: Chubb Andrew , Roberts Lyer Kirsten 
Published: August 2024

Abstract
Transnational Human Rights Violations (THRV) are infringements of individual rights that originate outside the jurisdiction in which they take effect. Ranging from violent and criminal forms of transnational repression through to coercion against targets’ family members abroad, digital surveillance, and legal intimidation, THRVs today generate widespread and systemic constraints on the exercise of human rights in jurisdictions around the world. At present, however, targets of THRVs typically find few avenues through which to raise complaints, receive assistance or pursue redress. This article proposes a new domestic institutional mechanism to directly address this situation. It first examines the mutually reinforcing, additive effects of transnational surveillance, coercion and censorship in the digital era. Next, it identifies relevant human rights standards showing state responsibilities to monitor and counter THRVs within their jurisdiction, and the growing recognition of additive, systemic effects of THRVs on broad populations. The third section examines policy responses in the United States, Australia, United Kingdom, and international organizations, noting that none has adequately addressed the contemporary nature and scope of THRVs as international standards require. The final section argues that to meet their obligations, states should establish Transnational Rights Protection Offices (TRPOs) to provide a clear contact point for targets to raise complaints and receive support; monitor and report on the situation of THRVs taking effect within the state’s jurisdiction; advise and inform government departments on THRV issues; and develop evidence-based policy recommendations. We conclude by laying out the rationale for its institutional status within National Human Rights Institutions (NHRIs).
Frequency shift in binary microlensing
Authors: Sarbaz Samaneh , Rahvar Sohrab 
Published: August 2024

ABSTRACT
Gravitational microlensing with binary lensing is one of the channels for detecting exoplanets. Due to the degeneracy of the lens parameters for the binary microlensing, additional features such as parallax and finite-size effects need to identify the lens parameters. The frequency-shift effect as the relativistic analogy of the gravity assist for the photons, is an extra observation that provides additional constraint between the lens parameters. In this work, we extend the application of the frequency-shift effect to binary microlensing and derive the frequency shift during the lensing and caustic crossing. The frequency shift for the binary lens is of the order of ${\Delta \nu }/{\nu }\sim 10^{-12}$. We also investigate the feasibility of detecting this effect by employing cross-correlation methods.
SDSS-IV MaNGA: stellar rotational support in disc galaxies versus central surface density and stellar population age
Authors: Wang Xiaohan , Luo Yifei , Faber S M , Koo David C , Mao Shude , Westfall Kyle B , Lu Shengdong , Wang Weichen , Bundy Kevin , Boardman N , Avila-Reese Vladimir , Fernández-Trincado José G , Lane Richard R 
Published: August 2024

ABSTRACT
We investigate how the stellar rotational support changes as a function of spatially resolved stellar population age ($D_n4000$) and relative central stellar surface density ($\Delta \Sigma _1$) for MaNGA isolated/central disc galaxies. We find that the galaxy rotational support indicator $\lambda _{R_\mathrm{e}}$ varies smoothly as a function of $\Delta \Sigma _1$ and $D_n4000$. $D_n4000$ versus $\Delta \Sigma _1$ follows a ‘J-shape’, with $\lambda _{R_\mathrm{e}}$ contributing to the scatters. In this ‘J-shaped’ pattern rotational support increases with central $D_n4000$ when $\Delta \Sigma _1$ is low but decreases with $\Delta \Sigma _1$ when $\Delta \Sigma _1$ is high. Restricting attention to low-$\Delta \Sigma _1$ (i.e. large-radius) galaxies, we suggest that the trend of increasing rotational support with $D_n4000$ for these objects is produced by a mix of two different processes, a primary trend characterized by growth in $\lambda _{R_\mathrm{e}}$ along with mass through gas accretion, on top of which disturbance episodes are overlaid, which reduce rotational support and trigger increased star formation. An additional finding is that star-forming galaxies with low $\Delta \Sigma _1$ have relatively larger radii than galaxies with higher $\Delta \Sigma _1$ at fixed stellar mass. Assuming that these relative radii rankings are preserved while galaxies are star forming then implies clear evolutionary paths in central $D_n4000$ versus $\Delta \Sigma _1$. The paper closes with comments on the implications that these paths have for the evolution of pseudo-bulges versus classical bulges. The utility of using $\rm D_n4000$–$\Delta \Sigma _1$ to study $\lambda _{R_\mathrm{e}}$ reinforces the notion that galaxy kinematics correlate both with structure and with stellar-population state, and indicates the importance of a multidimensional description for understanding bulge and galaxy evolution.
A complex node of the cosmic web associated with the massive galaxy cluster MACS J0600.1-2008
Authors: Furtak Lukas J , Zitrin Adi , Richard Johan , Eckert Dominique , Sayers Jack , Ebeling Harald , Fujimoto Seiji , Laporte Nicolas , Lagattuta David , Limousin Marceau , Mahler Guillaume , Meena Ashish K , Andrade-Santos Felipe , Frye Brenda L , Jauzac Mathilde , Koekemoer Anton M , Kohno Kotaro , Espada Daniel , Lu Harry , Massey Richard , Niemiec Anna 
Published: August 2024

ABSTRACT
MACS J0600.1-2008 (MACS0600) is an X-ray-luminous, massive galaxy cluster at $z_{\mathrm{d}}=0.43$, studied previously by the REionization LensIng Cluster Survey and ALMA Lensing Cluster Survey projects which revealed a complex, bimodal mass distribution and an intriguing high-redshift object behind it. Here, we report on the results of a combined analysis of the extended strong lensing (SL), X-ray, Sunyaev–Zeldovich (SZ), and galaxy luminosity-density properties of this system. Using new JWST and ground-based Gemini-N and Keck data, we obtain 13 new spectroscopic redshifts of multiply-imaged galaxies and identify 12 new photometric multiple-image systems and candidates, including two multiply-imaged $z\sim 7$ objects. Taking advantage of the larger areal coverage, our analysis reveals an additional bimodal, massive SL structure which we measure spectroscopically to lie adjacent to the cluster and whose existence was implied by previous SL-modelling analyses. While based in part on photometric systems identified in ground-based imaging requiring further verification, our extended SL model suggests that the cluster may have the second-largest critical area and effective Einstein radius observed to date, $A_{\mathrm{crit}}\simeq 2.16\, \mathrm{arcmin}^2$ and $\theta _{\mathrm{E}}=49.7^{\prime \prime }\pm 5.0^{\prime \prime }$ for a source at $z_{\mathrm{s}}=2$, enclosing a total mass of $M(\lt \theta _{\mathrm{E}})=(4.7\pm 0.7)\times 10^{14}\, \mathrm{M}_{\odot }$. These results are also supported by the galaxy luminosity distribution, and the SZ and X-ray data. Yet another, probably related massive cluster structure, discovered in X-rays 5 arcmin (1.7 Mpc) further north, suggests that MACS0600 is part of an even larger filamentary structure. This discovery adds to several recent detections of massive structures around SL galaxy clusters and establishes MACS0600 as a prime target for future high-redshift surveys with JWST.