bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ethos préalable et ethos (re) construit La transformation de l'humour légendaire de François Hollande
Authors: Jaubert Anna , Mayaffre Damon 
Published: November 2013

L’exercice de l’humour est fortement contraint dans le champ du discours politique, surtout lors d’une campagne présidentielle. Au-delà des programmes et des partis, élection uninominale et suffrage universel obligent, on voit les candidats se livrer à une guerre d’image. Pour François Hollande, opposé au président sortant, il s’agit de construire sa crédibilité. Cette contribution montre comment il corrige son ethos préalable de « monsieur petite blague » pour convertir son humour en force de frappe très contrôlée. À travers cette étude de cas, qui convoque en contrepoint politique Nicolas Sarkozy, et en contrepoint historique François Mitterrand, ce sont les conditions de félicité de l’humour en politique qui sont interrogées ; elles relèvent d’un ensemble de déterminations contextuelles où l’ethos discursif retravaille l’ethos préalable et où le locuteur négocie en permanence un rapport de place avec ses concurrents. Une telle approche dégage la solidarité de fait entre rhétorique et pragmatique.
Les enfants en danger dans la presse : la construction discursive de l'enfant agresseur et de l'enfant victime dans des narrations médiatiques
Authors: Ramos Rui , Cristina Martins Paula , Pereira Sara , Oliveira Madalena 
Published: November 2013

Ce texte présente des résultats issus d’un projet de recherche sur les images médiatiques des enfants en danger mené au Portugal. Il s’agit d’un projet interdisciplinaire, qui assume l’analyse de la problématique du danger et de la maltraitance envers les enfants dans sa configuration discursive et médiatique, à partir des textes présents en quatre quotidiens de grand tirage. Ce qui est en analyse est la construction discursive du rôle de l’enfant agresseur et de l’enfant victime dans les narrations médiatiques recueillies. On sait que la notion d’« enfant » est fréquemment associée à la faiblesse et à l’absence (d’autonomie, de responsabilité, de compétence, de pouvoir) du côté juridique, social, éducatif - et discursif. Aussi le rôle de victime est-il marqué par un cadre de faiblesse. Quand l’enfant est la victime, il ya une combinaison qui intensifie la vulnérabilité des deux conditions. D’autre part, l’idée d’enfant agresseur met en cause la représentation prototypique de l’enfance. Il semble donc stimulant d'analyser comment le rôle d’enfant agresseur ou victime est construit et quels sont les instruments linguistiques de cette construction ; quelles sont les voix évoquées (en particulier, si l’enfant a droit à se faire écouter) et quels sont les « frames » créés, à partir de quels instruments argumentatifs.
Osteomas of the craniofacial region: A case series and review of literature
Authors: Gundewar Sagar , Kothari Deepak S. , Mokal Nitin J. , Ghalme Amol 
Published: November 2013

ABSTRACT
Objective: 0 To discuss the clinical presentation, diagnosis and management of osteomas involving the craniomaxillofacial region. Materials and Methods: This study was conducted from June 2004 to March 2012 at our institute. A total of 12 cases between the ages of 10 and 50 years were managed with surgical excision and reconstruction. The criteria used to diagnose osteoma included radiographic and clinical features and histological confirmation of the specimen. The total follow-up period ranged from 6 to 24 months. Results: Out of 12 osteomas, 10 were peripheral and 2 were centrally located. Mandible involvement was seen in six patients, four involved the orbit, one the frontal bone and one the frontal bone with the skull base. All patients undergoing excision and reconstruction had a favourable aesthetic and functional outcome. There were no recurrences and no post-operative complications. Conclusion: Osteomas affect all age groups with no sex predilection and are usually clinically asymptomatic till they become large in size. Surgical excision and appropriate reconstruction is the mainstay of management. Surgery is indicated when lesion is symptomatic or actively growing and the surgical approach for exposure of the lesion should be case specific.
The effect of different positions on lower limbs skin perfusion pressure
Authors: Kawasaki Tota , Uemura Tetsuji , Matsuo Kiyomi , Masumoto Kazuyuki , Harada Yoshimi , Chuman Takahiro , Murata Tomoyuki 
Published: November 2013

ABSTRACTWe have encountered situations of patients with critical limb ischemia accompanied by pain at rest and necrosis, who hang their legs down from the bed during sleep. This lower limb position is known to be a natural position, which reduces pain in the lower extremity induced by ischemia. However, the effect of this position on blood flow of the lower extremity is poorly understood. We studied whether measurements of skin perfusion pressure (SPP) changes by leg position and the difference between healthy adults and patients with critical limb ischemia. The subjects of this study were 10 healthy adults and 11 patients with critical limb ischemia. Patients with critical limb ischemia, including both dorsum of foot and plantar of foot, having SPP of lower limbs of less than 40 mmHg (supine position) were the object of this study. SPP was measured on four positions (supine position, lower limbs elevation position, sitting position, and reclining bed elevation of 20° position). In sitting position, both the number of healthy adults and critical patients show significant increases in SPP compared with the other three positions. These results suggest that sitting position is effective to keep good blood stream of lower limbs not only in healthy adults but also in patients with critical limb ischemia. However, an appropriate leg position should not have lower limbs hang downwards for long periods time because edema is caused by the fall in venous return in lower limbs, and the wound healing is prolonged.Our clinical research could be more useful in the future, particularly in developing countries, for surgeons managing wounds in leg and foot and preserving ischemic limbs.
Aesthetical outcome after breast reconstruction using deep inferior epigastric perforator flap: Personal techniques
Authors: Gelati Chiara , Negosanti Luca , Fabbri Erich , Cipriani Riccardo 
Published: November 2013

ABSTRACT
Background: Now-a-days, deep inferior epigastric perforator (DIEP) flap breast reconstruction is widespread throughout the world. The aesthetical result is very important in breast reconstruction and its improvement is mandatory for plastic surgeons. Materials and Methods: The most frequent problems, we have observed in breast reconstruction with DIEP flap are breast asymmetry in terms of volume and shape, the bulkiness of the inferior lateral quadrant of the new breast, the loss of volume of the upper pole and the lack of projection of the inferior pole. We proposed our personal techniques to improve the aesthetical result in DIEP flap breast reconstruction. Our experience consists of more than 220 DIEP flap breast reconstructions. Results: The methods mentioned for improving the aesthetics of the reconstructed breast reported good results in all cases. Conclusion: The aim of our work is to describe our personal techniques in order to correct the mentioned problems and improve the final aesthetical outcome in DIEP flap breast reconstruction.
Expanding the spectrum of phenotypes associated with germline PIGA mutations: A child with developmental delay, accelerated linear growth, facial dysmorphisms, elevated alkaline phosphatase, and progressive CNS abnormalities
Authors: van der Crabben Saskia N. , Harakalova Magdalena , Brilstra Eva H. , van Berkestijn Frédérique M.C. , Hofstede Floris C. , van Vught Adrianus J. , Cuppen Edwin , Kloosterman Wigard , Ploos van Amstel Hans Kristian , van Haaften Gijs , van Haelst Mieke M. 
Published: November 2013

AbstractPhosphatidyl inositol glycan (PIG) enzyme subclasses are involved in distinct steps of glycosyl phosphatidyl inositol anchor protein biosynthesis. Glycolsyl phosphatidyl inositol‐anchored proteins have heterogeneous functions; they can function as enzymes, adhesion molecules, complement regulators and co‐receptors in signal transduction pathways. Germline mutations in genes encoding different members of the PIG family result in diverse conditions with (severe) developmental delay, (neonatal) seizures, hypotonia, CNS abnormalities, growth abnormalities, and congenital abnormalities as hallmark features. The variability of clinical features resembles the typical diversity of other glycosylation pathway deficiencies such as the congenital disorders of glycosylation. Here, we report the first germline missense mutation in the PIGA gene associated with accelerated linear growth, obesity, central hypotonia, severe refractory epilepsy, cardiac anomalies, mild facial dysmorphic features, mildly elevated alkaline phosphatase levels, and CNS anomalies consisting of progressive cerebral atrophy, insufficient myelinization, and cortical MRI signal abnormalities. X‐exome sequencing in the proband identified a c.278C>T (p.Pro93Leu) mutation in the PIGA gene. The mother and maternal grandmother were unaffected carriers and the mother showed 100% skewing of the X‐chromosome harboring the mutation. These results together with the clinical similarity of the patient reported here and the previously reported patients with a germline nonsense mutation in PIGA support the determination that this mutation caused the phenotype in this family. © 2013 Wiley Periodicals, Inc.
Expansion of the TARP syndrome phenotype associated with de novo mutations and mosaicism
Authors: Johnston Jennifer J. , Sapp Julie C. , Curry Cynthia , Horton Margaret , Leon Eyby , Cusmano‐Ozog Kristina , Dobyns William B. , Hudgins Louanne , Zackai Elaine , Biesecker Leslie G. 
Published: November 2013

AbstractThe TARP syndrome (Talipes equinovarus, Atrial septal defect, Robin sequence, and Persistent left superior vena cava) is an X‐linked disorder that was determined to be caused by mutations in RBM10 in two families, and confirmed in a subsequent case report. The first two original families were quite similar in phenotype, with uniform early lethality although a confirmatory case report showed survival into childhood. Here we report on five affecteds from three newly recognized families, including patients with atypical manifestations. None of the five patients had talipes and others also lacked cardinal TARP features of Robin sequence and atrial septal defect. All three families demonstrated de novo mutations, and one of the families had two recurrences, with demonstrable maternal mosaicism. © 2013 Wiley Periodicals, Inc.
Thiazolothiazole‐Containing Ambipolar Organic Semiconductor with Balanced Hole and Electron Mobility
Authors: Wang Yuanyuan , Huang Qiuliu , Liu Zhiqiang , Li Hongxiang 
Published: November 2013

AbstractThiazolothiazole‐containing organic semiconductors DH‐TTFZTT and DPCO‐TTFZTT were synthesized. Single crystal diffraction result revealed that DH‐TTFZTT adopts herringbone packing in the crystals, and strong S–S and S–π intermolecular interactions were found among neighboring molecules, which form a two‐dimensional network in the crystals. Thin‐film transistor characteristics showed that DH‐TTFZTT behaves as a p‐channel semiconductor with a hole mobility of approximately 2×10−2 cm2 V−1 s−1. DPCO‐TTFZTT‐based devices have balanced ambipolar performance, with hole and electron mobilities as high as 2.41×10−2 cm2 V−1 s−1 and 2.36×10−2 cm2 V−1 s−1 respectively, which are some of the highest values for thiazolothiazole derivatives.
Highly Enantioselective Preparation of Fluorinated Phosphonates by Michael Addition of α‐Fluoro‐β‐ketophosphonates to Nitroalkenes
Authors: Kwiatkowski Jacek , Lu Yixin 
Published: November 2013

AbstractFluorinated phosphonates are excellent surrogates of phosphates, outperforming the latter in terms of hydrolytic stability in biological systems while retaining similar activities. However, methods for preparing chiral fluorinated phosphonates are very limited. In this report, racemic α‐fluoro‐β‐ketophosphonates were used in stereoselective Michael addition to nitroalkenes promoted by trifunctional thiourea organocatalyst. Highly functionalised α‐fluoro‐β‐keto‐γ‐nitrophosphonates were obtained in high yields of 84–99% with excellent stereochemical control (96–99% ee and 3:1–34:1 d.r.).
Highly Selective Dimerization and Trimerization of Isobutene to Linearly Linked Products by Using Nickel Catalysts
Authors: Behr Arno , Rentmeister Nils , Seidensticker Thomas , Vosberg Jonas , Peitz Stephan , Maschmeyer Dietrich 
Published: November 2013

AbstractThe unique linear linkage of isobutene to generate highly valuable C8 precursors for plasticizers is feasible by using special nickel catalysts. (4‐Cyclooctene‐1‐yl)(1,1,1,5,5,5‐hexafluoro‐2,4‐acetylacetonato)nickel and aluminum‐alkyl‐activated nickel acetylacetonates produce isobutene dimers with high selectivities of up to 95 %. Moreover, selectivity for the head‐to‐head products (2,5‐dimethylhexenes) is remarkably high at up to 99 %. Additionally, novel C12 isobutene trimers are also formed with a very high selectivity of up to 99 % for the linear linkage. The trimer structure (2,5,8‐trimethylnonenes) reflects the stepwise characteristic of the reaction mechanism. Pathways of insertion and activation and the deactivation processes of the catalyst are discussed in detail.
Clickable SBA‐15 to Screen Functional Groups for Adsorption of Antibiotics
Authors: Gao Jinsuo , Zhang Xueying , Xu Shutao , Liu Jian , Tan Feng , Li Xinyong , Qu Zhenping , Zhang Yaobin , Quan Xie 
Published: November 2013

AbstractPharmaceutical antibiotics, as emerging contaminants, are usually composed of several functional groups that endow them with the ability to interact with adsorbents through different interactions. This makes the preparation of adsorbents tedious and time‐consuming to screen appropriate functionalized materials. Herein, we describe the synthesis of clickable SBA‐15 and demonstrate its feasibility as a screening material for the adsorption of antibiotics based on similar adsorption trends on materials with similar functional groups obtained by a click reaction and cocondensation/grafting methods.
Why Have We Made Neglect So Complicated? Taking a Fresh Look at Noticing and Helping the Neglected Child
Authors: Daniel Brigid 
Published: November 2013

The experience of chronic neglect is extremely harmful to children's physical, emotional, cognitive and behavioural development. As an area of research it has been traditionally described as neglected, and as an arena of practice it is viewed as complex and intractable. Over the last few decades, however, there has been a body of evidence building up to help with the understanding of the impact of neglect upon children and to guide intervention. This paper draws on experience as a researcher in the field to present some thoughts on our current understanding of neglect, and how we can move forward with more appropriate responses. It argues that existing evidence is not being used to best effect and that current protective systems, like those in the UK, are still struggling to provide an effective response to neglected children. The language of neglect has become over‐complicated and the systems and processes for assessment, planning and intervention are mired in bureaucracy. Some of these complexities are explored in more detail and a model is proposed that would support a more direct and straightforward response to children whose needs are not being met. Copyright © 2013 John Wiley & Sons, Ltd.‘current protective systems’‘are still struggling to provide an effective response to neglected children’Key Practitioner Messages:

Agencies and practitioners need to avoid being driven into developing complex responses by the complexity of neglect as a phenomenon.
Separate ‘child protection’ and ‘family support/child in need’ pathways are not helpful for neglected children.
In relation to a neglected child, practitioners can consider what the child needs and what they need people to think about and do on their behalf. Copyright © 2013 John Wiley & Sons, Ltd.
Hetero‐bivalent GLP‐1/Glibenclamide for Targeting Pancreatic β‐Cells
Authors: Hart Nathaniel J. , Chung Woo Jin , Weber Craig , Ananthakrishnan Kameswari , Anderson Miranda , Patek Renata , Zhang Zhanyu , Limesand Sean W. , Vagner Josef , Lynch Ronald M. 
Published: November 2013

AbstractG protein‐coupled receptor (GPCR) cell signalling cascades are initiated upon binding of a specific agonist ligand to its cell surface receptor. Linking multiple heterologous ligands that simultaneously bind and potentially link different receptors on the cell surface is a unique approach to modulate cell responses. Moreover, if the target receptors are selected based on analysis of cell‐specific expression of a receptor combination, then the linked binding elements might provide enhanced specificity of targeting the cell type of interest, that is, only to cells that express the complementary receptors. Two receptors whose expression is relatively specific (in combination) to insulin‐secreting pancreatic β‐cells are the sulfonylurea‐1 (SUR1) and the glucagon‐like peptide‐1 (GLP‐1) receptors. A heterobivalent ligand was assembled from the active fragment of GLP‐1 (7–36 GLP‐1) and glibenclamide, a small organic ligand for SUR1. The synthetic construct was labelled with Cy5 or europium chelated in DTPA to evaluate binding to β‐cells, by using fluorescence microscopy or time‐resolved saturation and competition binding assays, respectively. Once the ligand binds to β‐cells, it is rapidly capped and presumably removed from the cell surface by endocytosis. The bivalent ligand had an affinity approximately fivefold higher than monomeric europium‐labelled GLP‐1, likely a result of cooperative binding to the complementary receptors on the βTC3 cells. The high‐affinity binding was lost in the presence of either unlabelled monomer, thus demonstrating that interaction with both receptors is required for the enhanced binding at low concentrations. Importantly, bivalent enhancement was accomplished in a cell system with physiological levels of expression of the complementary receptors, thus indicating that this approach might be applicable for β‐cell targeting in vivo.
Isomerization During Olefin Metathesis: An Assessment of Potential Catalyst Culprits
Authors: Higman Carolyn S. , Plais Lucie , Fogg Deryn E. 
Published: November 2013

AbstractTwo ruthenium hydride complexes commonly proposed as agents of unintended isomerization during olefin metathesis are examined for their activity in isomerization of estragole, a representative allylbenzene. Neither proves kinetically competent to account for the levels of isomerization observed during cross‐metathesis of estragole by the second‐generation Grubbs catalyst. A structure–activity analysis of selected ruthenium hydride complexes indicates that higher isomerization activity correlates with a more electrophilic metal center.
ChemInform Abstract: Ca1‐xRExAg1‐ySb (RE: La, Ce, Pr, Nd, Sm; 0 ≤ x 1; 0 ≤ y ≤ 1): Interesting Structural Transformation and Enhanced High‐Temperature Thermoelectric Performance.
Authors: Wang Jian , Liu Xiao‐Cun , Xia Sheng‐Qing , Tao Xu‐Tang 
Published: November 2013

AbstractThe new Zintl phase‐based thermoelectric materials are synthesized from the elements using Pb as flux (alumina crucible, 900 °C, 24 h).
ChemInform Abstract: Mechanical Niobium Doping in Barium Titanate Electroceramics.
Authors: Velasco‐Davalos I. A. , Ruediger A. , Cruz‐Rivera J. J. , Gomez‐Yanez C. 
Published: November 2013

AbstractNb‐doped BaTiO3 ceramics are prepared by mechanical alloying of BaTiO3 and Nb2O5 powders in a planetary mill for up to 9 h followed by sintering at 1500 °C for 5 h.
ChemInform Abstract: Luminescent Carbon Dots in a New Magnesium Aluminophosphate Zeolite.
Authors: Wang Yanyan , Li Yi , Yan Yan , Xu Jun , Guan Buyuan , Wang Qiang , Li Jiyang , Yu Jihong 
Published: November 2013

AbstractThe structure of the new magnesium aluminophosphate molecular sieve materials (III) (obtained with 86 wt.% yield; monoclinic, space group P21/c, Z = 4) and (IV) (monoclinic, P21/n, Z = 4) are determined by single crystal XRD.
ChemInform Abstract: New Monoclinic Phase at the Composition Cu2SnSe3 and Its Thermoelectric Properties.
Authors: Fan Jing , Carrillo‐Cabrera Wilder , Akselrud Lev , Antonyshyn Iryna , Chen Lidong , Grin Yuri 
Published: November 2013

AbstractA new phase of Cu2SnSe3 is synthesized from stoichiometric mixtures of the elements (quartz ampule, 1173 K for 12 h and annealing at 850 K for 7 d).
ChemInform Abstract: Electrochemical Technique and Copper‐Promoted Transformations: Selective Hydroxylation and Amination of Arylboronic Acids.
Authors: Qi Hing‐Lin , Chen Dong‐Song , Ye Jian‐Shan , Huang Jing‐Mei 
Published: November 2013

AbstractBoronic acids are selectively converted by electrolysis into the corresponding phenols and amines in aqueous ammonia simply by changing the concentration of ammonia solution and the potential.
ChemInform Abstract: Efficient Ring Opening Reaction of Epoxides with Oxygen Nucleophiles Catalyzed by Quaternary Onium Salt.
Authors: Kim Jin Won , Cho Dae Won , Park Gyoosoon , Kim Sung Hong , Ra Choon Sup 
Published: November 2013

AbstractThe quarternary phosphonium salt Bu4PBr shows to be the most efficient catalyst for the title ring opening reaction.
ChemInform Abstract: Rh(III)‐Catalyzed Halogenation of Vinylic C—H Bonds: Rapid and General Access to Z‐Halo Acrylamides.
Authors: Kuhl Nadine , Schroeder Nils , Glorius Frank 
Published: November 2013

AbstractAdditionally representative application of this method for subsequent Sonogashira coupling is demonstrated.
ChemInform Abstract: Room Temperature Ambient Pressure (RTAP)‐Hydroformylation in Water Using a Self‐Assembling Ligand.
Authors: Straub Alexander T. , Otto Marina , Usui Ippei , Breit Bernhard 
Published: November 2013

AbstractThe Ru‐catalyzed hydroformylation of a variety of terminal alkenes is demonstrated to proceed under mild reaction conditions using the self‐assembling ligand PTS.
ChemInform Abstract: Three‐Component Chemoenzymatic Synthesis of Amide Ligated 1,2,3‐Triazoles.
Authors: Hassan Sidra , Tschersich Roxanne , Mueller Thomas J. J. 
Published: November 2013

AbstractNovozym 435 is used as efficient promotor for the aminolysis of a variety of methyl esters with propargylamine.
ChemInform Abstract: Catalytic Asymmetric Hydrogenation of δ‐Ketoesters: Highly Efficient Approach to Chiral 1,5‐Diols.
Authors: Yang Xiao‐Hui , Xie Jian‐Hua , Liu Wei‐Peng , Zhou Qi‐Lin 
Published: November 2013

AbstractThis method yields the title compounds in high yields and with excellent enantioselectivities under mild reaction conditions and with low catalyst loadings.
ChemInform Abstract: In situ Formed Bifunctional Primary Amine‐Imine Catalyst: Application to the Construction of Chiral Tertiary Alcohols Through Asymmetric Aldol‐Type Reaction.
Authors: Mao Zhijie , Zhu Xi , Lin Aijun , Li Weipeng , Shi Yan , Mao Haibin , Zhu Chengjian , Cheng Yixiang 
Published: November 2013

AbstractThe asymmetric aldol‐type reaction of cyclic ketones with β,γ‐unsaturated α‐keto esters and isatins is developed using chiral bisimines as precatalysts.
ChemInform Abstract: The Pd(0) Nanoparticles Stabilized by Collagen Fibers as a Recyclable Heterogeneous Catalyst for the Cyanation of Aryl Bromides Using K4Fe(CN)6 as Non‐toxic Source of Cyanide.
Authors: Bahari Siavash 
Published: November 2013

AbstractThe title reaction is applicable to a wide range of aromatic bromides with good yields and the catalyst can be recycled and reused without significant loss of activity.
ChemInform Abstract: Immobilization of L‐Lysine on Zeolite 4A as an Organic‐Inorganic Composite Basic Catalyst for Synthesis of α,β‐Unsaturated Carbonyl Compounds under Mild Conditions.
Authors: Zamani Farzad , Rezapour Mehdi , Kianpour Sahar 
Published: November 2013

AbstractThe immobilized lysine catalyst is shown to be highly active for the Knoevenagel reaction of various aromatic and aliphatic aldehydes with ethyl cyanoacetate.