bluuebunny/crossref_metadata_2025_split huggingface dataset:
Antibacterial and Biofilm Removal Strategies Based on Micro/Nanomotors in the Biomedical Field
Authors: Wu Wenlu , Wang Yuxin , Yang Haiyue , Chen Haixu , Wang Cong , Liang Junge , Song Yiran , Xu Shanshan , Sun Yuan , Wang Lei 
Published: July 2024

AbstractBacterial infection, which can trigger varieties of diseases and tens of thousands of deaths each year, poses serious threats to human health. Particularly, the new dilemma caused by biofilms is gradually becoming a severe and tough problem in the biomedical field. Thus, the strategies to address these problems are considered an urgent task at present. Micro/nanomotors (MNMs), also named micro/nanoscale robots, are mostly driven by chemical energy or external field, exhibiting strong diffusion and self‐propulsion in the liquid media, which has the potential for antibacterial applications. In particular, when MNMs are assembled in swarms, they become robust and efficient for biofilm removal. However, there is a lack of comprehensive review discussing the progress in this aspect. Bearing it in mind and based on our own research experience in this regard, the studies on MNMs driven by different mechanisms orchestrated for antibacterial activity and biofilm removal are timely and concisely summarized and discussed in this work, aiming to show the advantages of MNMs brought to this field. In addition, an outlook was proposed, hoping to provide the fundamental guidance for future development in this area.
Interface‐Interactive Nanoarchitectonics: Solid and/or Liquid
Authors: Ariga Katsuhiko 
Published: July 2024

AbstractThe methodology of nanoarchitectonics is to construct functional materials using nanounits such as atoms, molecules, and nanoobjects, just like architecting buildings. Nanoarchitectonics pursues the ultimate concept of materials science through the integration of related fields. In this review paper, under the title of interface‐interactive nanoarchitectonics, several examples of structure fabrication and function development at interfaces will be discussed, highlighting the importance of architecting materials with nanoscale considerations. Two sections provide some examples at the solid and liquid surfaces. In solid interfacial environments, molecular structures can be precisely observed and analyzed with theoretical calculations. Solid surfaces are a prime site for nanoarchitectonics at the molecular level. Nanoarchitectonics of solid surfaces has the potential to pave the way for cutting‐edge functionality and science based on advanced observation and analysis. Liquid surfaces are more kinetic and dynamic than solid interfaces, and their high fluidity offers many possibilities for structure fabrications by nanoarchitectonics. The latter feature has advantages in terms of freedom of interaction and diversity of components, therefore, liquid surfaces may be more suitable environments for the development of functionalities. The final section then discusses what is needed for the future of material creation in nanoarchitectonics.
Calcium Carbonate Nanocrystal Growth and Formation on Substrate by Thermal Chemical Vapor Deposition at Different Pre‐Cursor Concentration
Authors: Sulimai Nurul Hidah , Mohammad Jafar Salifairus , Khusaimi Zuraida , Malek Mohd. Firdaus , Abdullah Saifollah , Mahmood Mohamad Rusop 
Published: July 2024

AbstractRecent observations of crystallization by thermal chemical vapor deposition systems indicate that the classical mechanism of nucleation and growth is followed. Information on aragonite nanocrystal growth and formation on substrate have been lacking due to the lack of reports on diffusional growth that can observe calcium carbonate nucleation processes in thin film formation. This report is important due to the additive‐free method able to grow stable single‐phase nanocrystals without the presence of other phases, amorphous or impurities. This work demonstrates homogeneous nucleation occurred in gas phase reaction in a constant flow of carbon dioxide gas (100 sccm) with optimally 0.5 M calcium chloride precursor in atmospheric pressure at 400 °C resulting in a calculated crystallite size of 27.8 nm. X‐ray diffraction and energy dispersive spectrometer confirm the presence of calcium carbonate nanocrystal, whereas its structural changes are observed by its micrograph from field emission scanning electron microscope. The aim is to convey its importance in gaining control of aragonite nanocrystal morphology and structural properties, and thus generate nanocrystals with controlled phase. This work may contribute to development of more sensitive and crucial applications of calcium carbonate nanocrystal thin film such as in biosensors and biomedical.
Surface Cleaning of Oil Contaminants Using Bulk Nanobubbles
Authors: Hansen Helena H. W. B. , Ouyang Lingxi , Cha Haotian , Zhang Jun , Li Qin , Tan Beng Hau , Vashi Aditya , Nguyen Nam‐Trung , An Hongjie 
Published: July 2024

AbstractThe removal of oil from solid surfaces, such as textiles and plates, remains a challenge due to the strong binding affinity of the oil. Conventional methods for surface cleaning often require surfactants and mechanical abrasion to enhance the cleaning process. However, in excess, these can pose adverse effects on the environment and to the material. This study investigated how bulk nanobubble water can clean oil microdroplets deposited on surfaces like glass coverslips and dishes. Microscopy imaging and further image analysis clearly revealed that these microdroplets detached from both hydrophobic and hydrophilic surfaces when washed with bulk nanobubble water within a fluidic microchannel. Oil contaminant cleaning was also conducted in water as mobile phase to mimic the circumstances that occur in a dishwasher and washing machine. Cleaning on a larger scale also proved very successful in the removal of oil from a porcelain bowl. These results indicate that nanobubble water can easily remove oil contaminants from glass and porcelain surfaces without the assistance of surfactants. This is in stark contrast to negligible results obtained with a control solution without nanobubbles. This study indicates that nanobubble technology is an innovative, low‐cost, eco‐friendly approach for oil removal, demonstrating its potential for broad practical applications.
Enhancing Oxygen Evolution Reaction Performance of Metal‐Organic Frameworks through Cathode Activation
Authors: Dong Jie , Boukhvalov Danil W. , Lv Cuncai , Humphrey Mark G. , Zhang Chi , Huang Zhipeng 
Published: July 2024

AbstractDue to their abundant active sites and porous structures, metal‐organic frameworks (MOFs) have garnered significant interest as oxygen evolution reaction (OER) electrocatalysts. Nevertheless, the development of MOF s‐based electrocatalysts with efficient OER activity and excellent stability simultaneously still face challenges. Herein, a cathodic activation strategy was used to enhance the OER electrocatalytic performance of M‐HHTP for the first time, where M refers to Ni, Cu, Co, Fe, while HHTP denotes 2, 3, 6, 7, 10, 11‐hexahydroxytriphenylene. As a prototype, the activated Ni‐HHTP (HA‐Ni‐HHTP) demonstrates outstanding OER performance, with an overpotential as low as 140 mV at 20 mA cm−2 and a small Tafel slope of 78.7 mV−1, surpassing commercial RuO2 and rivaling state‐of‐the‐art MOFs‐based electrocatalysts. Characterizations and density functional theory calculations reveal that the superior performance of HA‐Ni‐HHTP is primarily ascribed to changes in semiconductor type, contact angle, and oxygen vacancy content induced by cathodic activation. Electrochemical impedance spectroscopy analysis using the transmission line model confirms that cathodic activation accelerates charge transport, enhancing the OER process. Furthermore, the cathodic activation strategy holds promise for improving the water oxidation performance of other MOFs such as Fe‐HHTP, Co‐HHTP, and Cu‐HHTP.
PROteolysis Targeting Chimeras: A new cutting‐edge nanomedicine for colorectal cancer
Authors: Maitra Swastika , Mukerjee Nobendu , Mukherjee Dattatreya , Ghosh Arabinda , Alexiou Athanasios T. 
Published: July 2024

AbstractColorectal cancer (CRC) is a prevalent malignancy with a high mortality rate, necessitating innovative treatment strategies. PROTACs (PROteolysis Targeting Chimeras) represent a promising therapeutic approach by targeting and degrading oncogenic proteins via the ubiquitin‐proteasome pathway. This study explores the potential of using exosomes as delivery vehicles for PROTACs to enhance treatment efficacy. Exosomes, due to their biocompatibility and inherent targeting capabilities, offer a precise method for delivering PROTACs to CRC cells, potentially overcoming challenges associated with traditional therapies such as drug resistance and off‐target effects. By harnessing the advantages of both exosome‐based delivery and PROTAC technology, this approach aims to improve targeted protein degradation and therapeutic outcomes in CRC treatment. Further research is required to optimize exosome engineering, ensure efficient PROTAC loading, and validate the safety and efficacy of this novel therapeutic strategy through preclinical and clinical trials.
Ionic‐Liquid‐Supported Magnetic Nanoparticles: Synthesis, Characterization, and Their Use for the Separation of Co and Ni from Li in Aqueous Solutions
Authors: Almeida Joana C. , Cardoso Celso E. D. , Neves Márcia , Trindade Tito , Freire Mara G. , Pereira Eduarda 
Published: July 2024

AbstractThe evolution of the electric vehicle market and the ongoing demand for lithium (Li), cobalt (Co) and nickel (Ni) for batteries production requires secondary sources for obtaining these elements. The recycling of Li‐ion batteries involves hydrometallurgical processes with potential environmental implications, hence there is an urgent need for sustainable and more efficient recycling methods. Functionalized colloidal magnetic nanomaterials have gained interest as sorbents as they can selectively bind and remove metal species from waters, allowing their easy recovery through magnetic separation. This work addresses the preparation and evaluation of silica‐coated magnetite nanoparticles (NPs), as alternative materials to recover Co and Ni from aqueous media, after their surface modification with 1‐methyl‐3‐propylimidazolium chloride. The magnetic nanosorbents were fully characterized and the influence of solution pH and amount of ILs on the NPs surface was evaluated. Our research allows us to conclude that IL functionalized magnetic nanoparticles can be explored as an alternative to hydrometallurgical processes for the separation of Co and Ni from alkaline lixiviates of spent lithium‐ion battery (LIB) powders.
The role of motivation in shaping social inclusion of people with intellectual disabilities in physical‐sports activity contexts
Authors: Ocete Calvo Carmen , Pérez‐Calzado Elena , Berástegui Ana , Franco Álvarez Evelia 
Published: July 2024

AbstractThe present study aims to test a model in which basic psychological needs (BPN) satisfaction in physical‐sport activity contexts is associated with self‐determined motivation, which, in turn, would predict the social inclusion of people with intellectual disabilities. A total of 286 people with intellectual disabilities (53.5% men) who reported engaging in physical‐sport activities responded to a validated questionnaire about the satisfaction of their BPN, motivation (using the Self‐determination index [SDI]), and social inclusion. A Pearson's bivariate correlation and structural equation modeling were conducted. The resulting model was reanalyzed in a multigroup analysis to test its invariance across self and proxy reports. Positive associations were found between the satisfaction of the BPN and the SDI. However, the SDI and social inclusion were positively associated only in proxy reports (βself = 0.07 vs. βproxy = 0.30). The tested model established positive relationships between the BPN and SDI in autonomy (βself = 0.21 vs. βproxy = 0.18), competence (βself = 0.47 vs. βproxy = 0.53), and relatedness (βself = 0.21 vs. βproxy = 0.23). Further research is needed to understand the factors leading to discrepancies between participants and proxies when relating the SDI to social inclusion in the context of physical‐sport activity. However, the results obtained suggest that it would be optimal to develop contexts of practice for people with intellectual disabilities in which the satisfaction of their BPN is favored and that this has a positive impact on their motivation and social inclusion.
Impact of dance classes on motor and cognitive functions and gut microbiota composition in multiple sclerosis patients: Randomized controlled trial
Authors: Adamová Louise Mária , Slezáková Darina , Hric Ivan , Nechalová Libuša , Berisha Genc , Olej Peter , Chren Matej , Chlapcová Adela , Penesová Adela , Minár Michal , Bielik Viktor 
Published: July 2024

AbstractEvidence suggests that multiple sclerosis (MS) induces a decline in motor and cognitive function and provokes a shift in gut microbiome composition in patients. Therefore, the aim of the study was to explore the effect of dance classes on the motor and cognitive functions and gut microbiota composition of MS patients. In this randomized controlled trial, 36 patients were randomly divided into two groups: the experimental group (n = 18) and the passive control group (n = 18). Supervised rock and roll and sports dance classes were performed for 12 weeks at a frequency of two times a week. Before and after the intervention, fecal samples were taken and the motor and cognitive function assessments were completed. Fecal microbiota were categorized using primers targeting the V3–V4 region of 16S rDNA. Our results revealed significant differences in mobility performance (T25‐FWT), attention and working memory (TMT B), and finger dexterity (9‐HPT) within the experimental group. Furthermore, we reported favorable shifts in gut microbial communities (an increase in Blautia stercoris and a decrease in Ruminococcus torques) within the experimental group. In conclusion, our randomized control trial on the effects of 12‐week dance classes in MS patients found significant improvements in motor and cognitive functions, with further moderate influence on gut microbiota composition.
Low-Level Dietary Clothianidin Exposure Preferentially Causes Prepupal Mortality of Monarch Butterflies (Danaus plexippus)
Authors: Bargar Timothy A. 
Published: July 2024

Abstract
Data from prior research indicate the prepupal stage of the monarch butterfly life cycle is more sensitive to clothianidin exposure than the larval stage. A set of experiments was conducted to determine if the dietary clothianidin exposures that cause prepupal mortality are environmentally relevant. Monarch larvae were raised from egg to pupae on clothianidin-contaminated swamp milkweed plants (Asclepias incarnata). Larval growth as well as larval and prepupal survival were monitored throughout the experiments, in which the exposures ranged from 1.4 to 2793.1 ng/g leaf. Exposures of 5.4 to 46.9 ng/g leaf resulted primarily in prepupal mortality, whereas higher exposures of 1042.4 to 2793.1 ng/g leaf resulted exclusively in larval mortality, indicating the prepupal stage is more sensitive to clothianidin exposure than the larval stage. A median lethal concentration and a 10% lethal concentration of 37 and 6 ng/g leaf, respectively, were estimated for prepupal mortality. Both effect concentrations are within the range of clothianidin concentrations reported in leaves collected from wild milkweed plants, indicating prepupal mortality is an environmentally relevant effect. Environ Toxicol Chem 2024;43:2039–2044. © 2024 The Authors. Environmental Toxicology and Chemistry published by Wiley Periodicals LLC on behalf of SETAC.
Analysis of posture and balance impairments in individuals with chronic nonspecific neck pain—An observational study
Authors: Prakash Nithin , Cleland Joshua , Kalyan Hemant K. , Roy Ajit Kumar , Jose Naveen Mathew , Harikesavan Karvannan 
Published: July 2024

AbstractBackgroundNeck pain is one of the most burdensome chronic musculoskeletal problems globally. Impaired proprioception is associated with chronic nonspecific neck pain as the structures of the cervical spine are crucial for proprioception and balance. There is a paucity of literature examining objective measures of balance and postural sway in patients with nonspecific neck pain.MethodsThis study was observational consisting 126 individuals (63 cases and 63 controls) who were recruited using convenience sampling. The demographics of the samples were collected and the postural and balance impairment was assessed using Biodex Balance SD. Mean, Median, and SD were obtained and the inferential analysis was done using the Whitney U Test and the level of significance was accepted at p < 0.05.ResultsThe subjects with neck pain showed had a lower static stability index, static sway index, static stability index—forward backward and static sway index lateral scores than the normal counterparts. There are significant differences in the overall static stability index (p < 0.001). There was a significant difference in static sway index (p = 0.003) and static stability index lateral (p = 0.004). There was no significant difference for static sway index forward and backward (p = 0.550) and lateral sway index (p = 0.711).ConclusionSubjects with neck pain had a lower static stability index, static sway index, static stability index—forward backward, and static sway index lateral scores than the normal counterparts and there was a significant difference between the static sway and static stability index in forward and backward directions as well as in lateral direction. These findings may help to assess the specific balance parameters and address the underlying causes of balance issues in patients with neck pain and also provide a comprehensive care to the patients.Clinical Trial RegistrationThe trial was registered with CTRI India with registration number: CTRI/2022/07/044222.
Non‐isothermal flow dynamics during reverse roll coating phenomena of non‐Newtonian polymer
Authors: Hanif Alia , Abbas Zaheer 
Published: July 2024

AbstractRoll coating plays a major role in industrial coating, including wallpapers, plastic and photographic films, sticky tapes, magnetic recordings, wrapping magazines and books, and so on. The current study proposes a mathematical model for a non‐isothermal, incompressible Sutterby fluid flowing through a narrow gap between two heated, counterrotating rollers. Lubrication approximation theory is used to simplify nondimensional expressions. The perturbation technique provides exact results for velocity profile, temperature, flow rate, and pressure gradient, whereas the numerical technique (Simpson rule) is used to compute the pressure profile and flow rate, respectively. The effects of the involved parameters on various physical characteristics like pressure, flow rate, temperature, pressure gradient, force, and power input are depicted in graphs and tabular form. A mechanism for controlling the coating thickness, power input, flow rate, separation force, and pressure distribution is provided by the material properties involved. With variations to a Sutterby fluid parameter and the velocity ratio K, both the pressure gradient and pressure decrease. It is significant to note that the temperature distribution is controlled by the velocities ratio and Brinkman number. Moreover, the separation point is shifted towards the nip area and the coating thickness on the web reduces with increasing velocities ratio K.
Atypical hemolytic‐uremic syndrome after COVID‐19 vaccine: A case report
Authors: Campos Marcos Adriano Garcia , Ataídes Rômullo José Costa , Ferreira Maxwell Cabral , Alves Adriano Soares , Silva Gyl Eanes Barros 
Published: July 2024

AbstractBackgroundThe emergence of new SARS‐CoV‐2 variants and the global COVID‐19 pandemic spurred urgent vaccine development. While common vaccine side effects are well‐documented, rare adverse events necessitate post‐marketing surveillance. Recent research linked messenger RNA vaccines to thrombotic microangiopathy (TMA), a group of syndromes characterized by microvascular hemolytic anemia and thrombocytopenia. This report describes a new‐onset atypical hemolytic‐uremic syndrome (aHUS) occurring after COVID‐19 vaccination and complements recent literature.Case PresentationA previously healthy 25‐year‐old woman developed malaise, nausea, edema, and renal dysfunction 60 days postvaccination. Laboratory findings confirmed TMA diagnosis. Genetic testing for complement system mutations was negative. Kidney biopsy supported the diagnosis, and the patient required hemodialysis.ConclusionThis case illustrates the rare occurrence of aHUS following COVID‐19 vaccination, with unique characteristics compared to previous reports. Despite the critical role of vaccination in pandemic control, emerging adverse events, such as vaccine‐related TMA, must be recognized and investigated. Additional clinical trials are imperative to comprehend the clinical features and pathophysiological mechanisms underlying TMA associated with COVID‐19 vaccination.
Res‐MulFra: Multilevel and Multiscale Framework for Brain Tumor Segmentation
Authors: Huang Dan , Qiu Luyi , Liu Zifeng , Ding Yi , Cao Mingsheng 
Published: July 2024

ABSTRACTIn clinical diagnosis and surgical planning, extracting brain tumors from magnetic resonance images (MRI) is very important. Nevertheless, considering the high variability and imbalance of the brain tumor datasets, the way of designing a deep neural network for accurately segmenting the brain tumor still challenges the researchers. Moreover, as the number of convolutional layers increases, the deep feature maps cannot provide fine‐grained spatial information, and this feature information is useful for segmenting brain tumors from the MRI. Aiming to solve this problem, a brain tumor segmenting method of residual multilevel and multiscale framework (Res‐MulFra) is proposed in this article. In the proposed framework, the multilevel is realized by stacking the proposed RMFM‐based segmentation network (RMFMSegNet), which is mainly used to leverage the prior knowledge to gain a better brain tumor segmentation performance. The multiscale is implemented by the proposed RMFMSegNet, which includes both the parallel multibranch structure and the serial multibranch structure, and is mainly designed for obtaining the multiscale feature information. Moreover, from various receptive fields, a residual multiscale feature fusion module (RMFM) is also proposed to effectively combine the contextual feature information. Furthermore, in order to gain a better brain tumor segmentation performance, the channel attention module is also adopted. Through assessing the devised framework on the BraTS dataset and comparing it with other advanced methods, the effectiveness of the Res‐MulFra is verified by the extensive experimental results. For the BraTS2015 testing dataset, the Dice value of the proposed method is 0.85 for the complete area, 0.72 for the core area, and 0.62 for the enhanced area.