bluuebunny/crossref_metadata_2025_split huggingface dataset:
ANALISIS PERSONAL BRANDING PRATAMA ARHAN MELALUI MEDIA SOSIAL INSTAGRAM PADA AKUN INSTAGRAM @Pratamaarhan8
Authors: Faikoh Faikoh Umairoh 
Published: August 2024

Global trends are marked by the presence of social media. One of them is Instagram which can be used as a place to build a person's personal branding. In this research, personal branding is also a very important part for athletes, especially the U-23 Pratama Arhan national team soccer players. This research aims to determine Pratama Arhan's personal branding through the social media Instagram and the interactions that occur therein through the features on Instagram. This research is descriptive qualitative in nature with the main key informant being the Instagram account @pratamaarhan8. Data collection was carried out by documenting interviews with followers and literature studies related to personal branding. Researchers tried to analyze the social media account instagram@pratamaarhan8 in building personal branding with eight concepts coined by Peter Montoya, namely: Specialization, Leadership, Personality, Difference, Visibility, Unity, Firmness, good name. The results of this research, Pratama Arhan succeeded in building personal branding through his Instagram social media by utilizing several features on Instagram and the eight personal branding concepts coined by Peter Montoya.
Anti-IL-4Rα monoclonal antibody (CM310) in patients with chronic rhinosinusitis with nasal polyps (CROWNS-2): Rationale and design of a multicenter, randomized, double-blind, placebo-controlled, parallel-group study
Authors: Shen Shen , Yan Bing , Wang Ming , Wu Di , Wang Chengshuo , Zhang Luo 
Published: August 2024

Background:
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a heterogeneous disease that affects a large proportion of the global population. The treatment of CRSwNP, especially eosinophilic CRSwNP (ECRSwNP), has always been of great obstacle. Our previous phase 2 trial showed that CM310, a monoclonal antibody that targets interleukin-4 receptor alpha, was both safe and effective in reducing the size of nasal polyps, improving symptom scores, and increasing the quality of life for those with severe ECRSwNP.

Objective:
This phase 3 trial aims to evaluate the efficacy, safety, pharmacokinetic, pharmacodynamic, and immunogenicity of CM310 in participants with CRSwNP.

Result:
The CROWNS-2 is a multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 3 trial. The study consisted of a screening/run-in period (up to 4 weeks), a treatment period (24-week double-blind treatment period plus 28-week maintenance period), and a safety follow-up period (8 weeks). The study planned to enroll 180 participants with CRSwNP (at least 60% of ECRSwNP) to receive CM310 300 mg/placebo every 2 weeks (Q2W) subcutaneously for a total of 12 doses in double-blind treatment period and 300 mg CM310 Q2W subcutaneously for a total of 14 doses in maintenance period. Enrolled participants continued to use mometasone furoate nasal spray throughout the study. The primary endpoints are a change from baseline in nasal polyp score and nasal congestion score at week 24 between CM310 and placebo in both ECRSwNP and CRSwNP.

Conclusion:
The CROWNS-2 is a multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 3 clinical study to evaluate the efficacy and safety of CM310 in patients with CRSwNP.

Trial registration:
NCT05436275.
Emotional Consequences of Gender-Based Violence: Influences on Ratnamala’s Decision-Making in The Story of Felanee
Authors: Boruah Bhagirath , Bari Rachel 
Published: August 2024

This study analyses how the emotional consequences of gender-based violence (GBV) shape Ratnamala's decision to elope with Kinaram in Arupa Patangia Kalita's novel, The Story of Felanee (2011). Focusing on the sociocultural practices of 1940s Assam, this research reveals how GBV, particularly the oppressive norms of widowhood prevalent in Ratnamala's patriarchal, upper-caste Hindu community, profoundly impacts her emotional landscape and ultimately fuels her act of resistance through elopement. By integrating the decision-making framework of Ernst and Paulus with Damasio's Somatic Marker Hypothesis and Kahneman and Tversky's Prospect Theory, this paper provides a nuanced understanding of the interplay between GBV, emotional responses, and Ratnamala's pursuit of autonomy and happiness.
Elevated Titanium Levels After Revision Total Hip Caused by Previously Unreported Mechanism
Authors: Josephson Brian G. , Damron Timothy A. 
Published: August 2024

Introduction:
Metallosis from total hip arthroplasty is usually due to trunnionosis and is associated with elevated serum cobalt and chromium levels. Titanium levels usually remain normal.

Methods:
Here, we report two rare cases of elevated titanium levels, both with the same mechanism, which is a previously unreported cause of titanium metallosis.

Results:
In these cases, contact between cables and the titanium stem were the source.

Discussion:
Reports of isolated high titanium levels associated with total hip arthroplasty are rare. These cases illustrate a new mechanism from which this situation may arise.
Workers particularly sensitive to cardiovascular risk
Authors: Carlos Álvarez-Fernández , Manuel Vaquero-Abellán , Manuel Romero-Saldaña , Carlos Álvarez-López 
Published: August 2024

<p><strong>Background:</strong> Of the 607 fatal occupational accidents that occurred in Spain in 2016, 37.9% were due to ischemic heart disease and stroke. Working conditions such as night work, noise or respiratory contaminants were associated with a higher cardiovascular incidence. The aim of the present study was to assess whether health surveillance in workers exposed to these conditions should include assessment of cardiovascular risk. <strong>Subjects and methods: </strong>A cross-sectional study was conducted in 680 workers in a public administration. The qualification of working conditions was obtained from the company risk assessment and from personal, anthropometric and analytical data, which allowed the assessment of cardiovascular risk in the medical examination performed in 2015. <strong>Results: </strong>30.1% of the sample were exposed to these working conditions, with significant differences by sex (37% in men, 11.9% in women, p&lt;0.05). According to REGICOR, 13.2% of those exposed were classified as particularly sensitive to cardiovascular risk. <strong>Conclusions:</strong> A large percentage of workers are exposed to TC related to a greater prevalence of cardiovascular pathology. The percentage of workers classified as especially sensitive to cardiovascular risk among those exposed suggests that this risk should be assessed in occupational health surveillance when there are working conditions related to cardiovascular pathology.</p>
FIBROTERAPIA COM MODULADORES DE CFTR PARA PACIENTES COM FIBROSE CÍSTICA- ARTIGO DE REVISÃO
Authors: Silva Daniela Diniz Martins da , Chaimowicz Beatriz de Faria , Santos Clara Chagas Barbosa , Pimenta Clara Rubião , Sternick Letícia Ribeiro 
Published: August 2024

INTRODUÇÃO: A fibrose cística é uma doença genética na qual ocorre uma mutação no gene codificador da proteína CFTR que regula o transporte de cloro na membrana. Com isso, há prejuízo na reabsorção de algumas substâncias, o que acaba prejudicando diversos órgãos. Ainda não há uma cura descoberta mas, recentemente, estão sendo estudados medicamentos moduladores de CFTR, que, quando combinados e aplicados em pacientes homozigotos para o gene F508del, formam uma terapia eficaz para a doença. OBJETIVO: Discorrer sobre a pesquisa acerca da terapia medicamentosa usada no tratamento da doença fibrose cística. MÉTODO: Revisão literária integrativa de artigos dos bancos de dados SciELO, PubMed, NCBI, The New England Journal of Medicine, UpToDate, utilizando como descritores os termos em português e inglês ‘’Cystic Fibrosis’’, ‘’Tezacaftor’’, ‘’Ivacaftor’’ e ‘’CFTR Modulators’’ em artigos publicados entre 2017 e 2019. RESULTADO: Houve melhora do quadro respiratório com aumento do volume expirado forçado nas duas terapias, sendo que as combinadas ou triplas, (VX-tezacaftor-ivacaftor) se mostraram a mais eficazes. CONCLUSÃO: Com essa revisão, foi possível compreender a relação de eficácia dos remédios ivacaftor e tezacaftor (associados ou não com VX-659 e o VX-445) e observar os efeitos positivos dessa terapia para um melhor prognóstico da fibrose cística, podendo dar esperança de melhora na qualidade de vida de pacientes com essa doença.
Perancangan Aplikasi Register Berbasis Web Di Dinas Pendidikan Kota Pematangsiantar
Authors: Damanik Rissa Azzahra , Irawati Novica 
Published: August 2024

Dinas Pendidikan Kota Pematansiantar masih mengandalkan pengolahan manual pada sebagian besar dokumennya sehingga menyebabkan rendahnya efisiensi dan tingginya risiko kesalahan. Untuk mengatasi permasalahan tersebut, dikembangkanlah aplikasi registry berbasis web yang bertujuan untuk meningkatkan efektifitas dan efisiensi pengelolaan data. Aplikasi ini dikembangkan dengan menggunakan metodologi pengembangan perangkat lunak berbasis air terjun yang meliputi tahap analisis, desain, implementasi, pengujian, dan pemeliharaan. Fitur utama aplikasi ini antara lain registrasi online, pengelolaan data siswa, guru, dan sekolah, serta pelaporan berbasis web. Dengan adanya aplikasi ini diharapkan proses administrasi pada Dinas Pendidikan Kota Pematansiantar dapat dilaksanakan lebih cepat, akurat dan terstruktur. Pengujian menunjukkan bahwa aplikasi ini memenuhi kebutuhan Anda dan berfungsi dengan baik di berbagai perangkat yang mendukung akses web.
Energy Analysis and Economy Performance of a Hybrid Solar Dryer for Drying Coffee
Authors: Suherman Suherman , Hadiyanto Hadiyanto , Franz Nicholas , Kamandjaja Vimala , Sinuhaji Tubagus Rayyan Fitra 
Published: August 2024

This work studies the effect of the drying temperature on the profile of the water content, drying rate, drying efficiency, economic performance, and the quality of Robusta and Arabica coffee beans using the hybrid solar dryer. The drying instrument with the help of LPG heating is used in this research with a specified temperature of 40 ℃, 50 ℃, and 60 ℃. The research is conducted on a sunny day for 1 day for each temperature and coffee beans. The temperature profile shows that the lowest water content in the study is 60 ℃. The drying rate for both 50 ℃ and 60 ℃ are similar and the highest average efficiency of the instrument is at 50 ℃ for both Robusta and Arabica beans. The dominant peak in GCMS analysis result of coffee samples was caffeine with a total area percentage of 30.89%, the description of the coffee bean structure using SEM test resulted in a hole size of 5-10 µm, the obtained fat content was 1.6%, the obtained protein content 17.3%. A hybrid solar dryer is an environmentally friendly solution that enables faster coffee drying, with a payback period of 1.5 years for both coffee bean types.
NEUROCRIPTOCOCOSE: UMA COMPARAÇÃO ENTRE A TERAPÊUTICA REALIZADA COM A ANFOTERICINA B E O FLUCONAZOL
Authors: Freire Ludmylla Ellen Ferreira , Bezerra Lucas Frederico Miranda , Samineses João Gabriel Queiroz , Santos Lucas Clovisan Camargo , Sá Gabriela Sebastiana Barbosa , Nascimento Jouwsen Henrieth Reis Andrade , Costa Hayla Thatielle Cardoso de Oliveira , Mota Isaac Dias , Silva Elias Ribeiro Nunes da , Rios Pedro Igor de Sousa , Gomes Diogo Antonio Paiva , Almeida Andreya Lorena Luso de , Santos Neto Jamil dos , Amaral Maria Eduarda Brito , Ferraz Eloismaile Leite 
Published: August 2024

A Criptococose se refere a uma doença fúngica oportunista que possui predileção pelo Sistema Nervoso Central (SNC). Apesar de acometer principalmente pacientes imunossuprimidos, a infecção também pode atingir indivíduos imunocompetentes. Ela acomete, em maior escala, homens entre a terceira e a quinta década de vida devido à incidência de infecção pelo Vírus da Imunodeficiência Humana (HIV). A indução é feita com a Anfotericina B (AnB) associada ou não à Flucitosina, a consolidação com o Fluconazol (FLZ), seguida da fase de manutenção. Todavia, a Flucitosina não é vendida no país e em casos mais graves utiliza-se apenas a AnB ou uma combinação entre ela e o FLZ. Esse tratamento foi o mais utilizado na fase de indução e os desfechos foram, em sua maioria, favoráveis. Mas é preciso destacar que isso só foi possível graças a um tempo maior de tratamento. O FLZ apresentou maiores taxas de resistência, mas isso não pode ser considerado como uma verdade absoluta, pois há relatos que mostram pacientes evoluindo melhor com o FLZ ao invés de AnB. A AnB possui índices de resistência menores, contudo mais efeitos colaterais. Portanto, cada caso deve ser analizado e a evolução clínica do paciente deve predizer o uso da AnB ou do FLZ.
Altas habilidades no ensino: Revisão de literatura
Authors: Da Silva Juliana Rodrigues Faria 
Published: August 2024

Este estudo qualitativo e descritivo em sua metodologia buscou levantar artigos na base de dados Scielo dos últimos cinco anos, ou seja de 2019 a 2023, utilizando os descritores "Altas Habilidades" AND "Educação". O objetivo geral deste estudo foi compreender as altas habilidades e superdotação (AH/SD) no sistema educacional. Os objetivos específicos foram: a) investigar como a literatura aborda o tema das AH/SD; b) identificar, por meio da leitura de artigos científicos, como o direito à educação inclusiva é garantido em relação às AH/SD nas escolas. Os estudos, as AH/SD geralmente apontam que uma pessoa pode inicialmente ter algumas vantagens em relação aos seus pares, porém também enfrentam desafios e vulnerabilidades. Quanto à legislação que está em vigor para assegurar a educação inclusiva tanto para pessoas com AH/SD quanto para qualquer outra pessoa, com ou sem deficiência, há pontos de destaque na lei para garantir o direito à educação inclusiva. Cabe ressaltar que todos contribuem nesse processo de educar e é necessário fornecer orientações aos profissionais da educação e pais, pois desempenham um papel importante nesse contexto.
The Impact of Digitalization on Improving Vocational Skills Mastery for Learning Disabilities Special Education Needs Students (SENs): A Literature Review Analysis
Authors: Ayaoo Dhevendren , Gunarhadi Gunarhadi , Yasin Mohd Hanafi bin Mohd , Subagya Subagya 
Published: August 2024

This literature review analysis explores the growing use of digital tools in vocational training programs for students with learning disabilities (LD). Through a review of literature (2014-2024), more than 20 articles related to the topic, examines the potential of digital tools to address the specific learning challenges faced by students with LD and improve their vocational skill mastery. This analysis is expected to reveal the effectiveness of various digital tools such as simulations, gamified learning platforms, and personalized learning technologies. While the research suggests promise in improved skill acquisition, enhanced engagement, and development of essential workplace skills, challenges like teacher training and accessibility concerns are also identified. Emerging trends in the use of virtual reality, artificial intelligence, and gamification for personalized learning are explored, highlighting the potential for further advancements in this field. Overall, the analysis underscores the significant role digital tools can play in creating more inclusive and effective vocational training programs, ultimately empowering students with LD to achieve successful career outcomes.
Development of Kotak Saran for Unit of Measurement Learning in SLB Negeri 2 Sawahlunto
Authors: Paramuditha Widi Kumara Jaga , Padri Maizal , Handayani Fitri , Harianti Yutri , Rahmahtrisilvia Rahmahtrisilvia , Tsaputra Antoni , Irdamurni Irdamurni , Iswari Mega 
Published: August 2024

This research was motivated by the lack of innovative teaching tools in special education settings, one of which is learning the conversion of units of measurement. The research was conducted at SLB Negeri 2 Sawahlunto with the target of intellectual

disability students who face challenges in understanding math concepts related to units of measurement. This research aims to develop learning media in the form of Kotak Saran (Unit of Measurement Conversion). Using research and development methods with 4D design. The subject of this research and development trial was by related experts such as media experts, tools, and learning for students with disabilities. As well as a practicality test by an educator and a student of intellectual disability. The data collection tool is a questionnaire instrument for the validity of the Kotak Saran media and a response instrument for the assessment of the Kotak Saran media. The data analysis technique used is descriptive data analysis technique. The results of this study indicate that the Kotak Saran learning media is useful and feasible as a learning media in the conversion of units of measurement with the acquisition of a validation value of 92.40% and a practicality test of 82.5%. The final form of this product is in the form of learning media packaged in the form of an android application so that it can be opened anywhere and anytime via an android smartphone.
Penerapan Keterampilan Membaca Sekilas dalam Memahami Karya Ilmiah
Authors: Jasmine Malaika Ramadhani  , Putri Nadiarahma  , Elsa Nabila Mustofa  , Mahmudah Fitriyah Z.A.  
Published: August 2024

The purpose of this study is to investigate the effectiveness of applying reading skills at a glance in improving understanding of scientific work. The method used in this study was library study. The data in this study were obtained from reading reference books and journal articles. The result of this study is that by applying fleeting reading skills in understanding scientific work, we can improve academic literacy, help students and researchers access information quickly, and form critical and effective individuals in managing information. A fleeting reading skill is not just a technical skill, but a learning strategy that supports the achievement of higher education goals. In extensive reading, these skills are key to achieving an overall picture and basic information of scientific texts. In addition, the application of fleeting reading skills in scientific work provides significant benefits, such as time efficiency and the ability to quickly identify key information, although deep reading remains essential for comprehensive understanding.
Potensi dan Strategi Pengembangan Usaha Ternak Sapi Potong di Kabupaten Nagekeo
Authors: Wuda Victoria , Krova Maria , R. Lole Ulrikus , A. Nale Agus 
Published: August 2024

Penelitian ini bertujuan untuk menganalisis kedudukan komoditas ternak sapi potong sebagai sector basis atau non basis dan merumuskan strategi pengembangan usaha ternak sapi potong di Kabupaten Nagekeo. Penelitian ini telah dilaksanakan di Kecamatan Aesesa dan Kecamatan Boawae pada bulan juni 2023. Metode penelitian yang digunakan adalah metode survei untuk memperoleh data primer dan sekunder melalui teknik observasi, wawancara dan dokumentasi. Pengambilan contoh dilakukan melalui tiga tahap. Tahap pertama dilakukan pada tingkat kecamatan secara purposive sampling, tahap kedua penentuan desa contoh dan tahap ketiga penentuan peternak contoh sebagai responden sebanyak 60 orang secara acak non proposional. Data dianalisis menggunakan analisis location quotiont (LQ) dan analisis SWOT. Hasil penelitian menunjukkan bahwa nilai LQ Kabupaten Nagekeo 0,75 dan bukan merupakan wilayah basis. Hasil analisis SWOT menunjukkan bahwa usaha ternak sapi potong berada pada kuadran satu dan strategi adalah strategi agresif yang mendukung penuh pertumbuhan dan pembangunan usaha ternak sapi di Kabupaten Nagekeo. Strateginya adalah meningkatkan produktivitas ternak dan meningkatkan etos kerja peternak untuk memenuhi permintaan pasar, meningkatkan keterampilan peternak melalui pelatihan dan pemberdayaan peternak untuk meningkatkan kualitas hasil ternak.
Cerita Hipertensi : Pengabdian Masyarakat Aktivitas Fisik Pencegah Hipertensi
Authors: Saptono Fahrurodzi Denny , Zulianing Dewi Aldise , Azhari Nugrahani Nur’Aini , Prasetyo Aji Dony , Rolavi Jannah Fadilah , Amelta Sahda Renaya , Sukma Anggreani Shafira , Madrinia Rahmawati Meisya , Rizky Dwi Achmad Yanuar , Adi Setyaningsih Putri 
Published: August 2024

Hipertensi atau dikenal dengan tekanan darah tinggi merupakan kondisi dimana tekanan darah pada pembuluh darah meningkat secara terus-menerus. Metode yang dilakukan dengan cara sosialisasi secara langsung kepada lansia terkait pengetahuan hipertensi. Kegiatan penyuluhan ini dilaksanakan di Dusun Banaran, Desa Tegalsari, Kecamatan Weru, Kabupaten Sukoharjo, pada tanggal 11 Januari 2024. Sasaran dari kegiatan ini adalah lansia di Dusun Banaran yang rata rata berumur 50-60 keatas sebelum dilakukan edukasi dilakukan pre test kepada para lansia lalu Bagian inti dari kegiatan ini adalah pemberian materi hipertensi, yang meliputi pengertian hipertensi, fakta hipertensi, faktor penyebab hipertensi, cara pencegahan dan penaggulangan hipertensi, pengertian aktivitas fisik, pentingnya melakukan aktivitas fisik. Setelah dilakukan pemberian edukasi terkait hipertensi, kegiatan selanjutnya adalah post-tes. Hasil post-test menunjukkan para lansia sudah bisa menjawab semua pertanyan yang diberikan dengan benar setelah mendengarkan materi yang telah dipaparkan
Peningkatan Pengetahuan Remaja Putri Tentang Stunting Melalui Penggunaan Media Video Animasi Berbasis Platform Instagram
Authors: Sulistyowati, Sulistyowati , Kandriasari Annis , Rusilanti Rusilanti 
Published: August 2024

Penelitian ini bertujuan untuk untuk mengukur peningkatan pnerapan media video animasi berbasis Platform Instagram terhadap hasil pengetahuan remaja putri tentang stunting. Penelitian ini dilakukan secara online di Whatsapp Group. Penggunaan metode pada penelitian ini adalah pre-eksperimen dengan sampel 30 orang remaja putri. Data dikumpulkan dengan desain penelitian one group pre-test post-test design pilihan ganda 20 butir soal. Butir soal telah di uji validitas sehingga diperoleh hasil valid pada tiap butir dengan nilai lebih besar atau sama dengan 0,3; kemudian dilakukan uji reliabilitas dengan hasil sangat reliabel sebesar 1,0; dan diuji taraf kesukaran butir soal yang diperoleh hasil 21 butir pada kategori kesukaran sedang serta 9 butir pada kategori kesukaran mudah. Hasil teknik analisis data diperoleh nilai rata – rata pre-test sebesar 56,666 dan nilai rata-rata post-test sebesar 88,33 artinya terdapat selisih nilai sebesar 31,667. Dapat disimpulkan bahwa penerapan media video animasi berbasis Platform Instagram dinilai meningkatkan rata – rata pengetahuan remaja putri karena terdapat peningkatan pengetahuan secara signifikan dari hasil pre-test dan post-test yang telah diuji dengan N-gain, dari hasil uji N-gain diperoleh nilai 0,701 termasuk peningkatan pengetahuan tinggi dengan presentase 70,329% tingkat keefektifan yang baik karena antusias remaja putri untuk mengetahui tentang stunting