bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association between phthalates and externalizing behaviors and cortical thickness in children with attention deficit hyperactivity disorder
Authors: Park S. , Lee J.-M. , Kim J.-W. , Cheong J. H. , Yun H. J. , Hong Y.-C. , Kim Y. , Han D. H. , Yoo H.J. , Shin M.-S. , Cho S.-C. , Kim B.-N. 
Published: November 2014

Background.Previous studies have implicated the relationship between environmental phthalate exposure and attention deficit hyperactivity disorder (ADHD) symptoms of childhood, but no studies have been conducted in children who have a confirmed diagnosis of ADHD obtained through meticulous diagnostic testing. We aimed to determine whether phthalate metabolites in urine would be higher in children with ADHD than in those without ADHD and would correlate with symptom severity and cortical thickness in ADHD children.Method.A cross-sectional examination of urine phthalate metabolite concentrations was performed; scores for ADHD symptoms, externalizing problems, and continuous performance tests were obtained from 180 children with ADHD, and brain-imaging data were obtained from 115 participants. For the control group, children without ADHD (N = 438) were recruited. Correlations between phthalate metabolite concentrations and clinical measures and brain cortical thickness were investigated.Results.Concentrations of phthalate metabolites, particularly the di(2-ethylhexyl) phthalate (DEHP) metabolite, were significantly higher in boys with ADHD than in boys without ADHD. Concentrations of the di-n-butyl phthalate (DBP) metabolite were significantly higher in the combined or hyperactive-impulsive subtypes compared to the inattentive subtype, and the metabolite was positively correlated with the severity of externalizing symptoms. Concentrations of the DEHP metabolite were negatively correlated with cortical thickness in the right middle and superior temporal gyri.Conclusions.The results of this study suggest an association between phthalate concentrations and both the diagnosis and symptom severity of ADHD. Imaging findings suggest a negative impact of phthalates on regional cortical maturation in children with ADHD.
PREACHERS AND HEARERS IN REVOLUTIONARY LONDON: CONTEXTUALISING PARLIAMENTARY FAST SERMONS
Authors: Hughes Ann 
Published: November 2014

ABSTRACTStudies of preaching in England during the 1640s and 1650 have focused on the high-profile sermons, preached before the parliament on fast days and other special days of thanksgiving, relying in particular on analysis of preachers’ texts as published in print. This paper explores ways of placing the fast sermons in broader contexts, drawing on the lively scholarship on early modern sermons that presents them as events as well as texts, dynamic encounters between preachers and hearers. This paper thus explores the responses of conscientious hearers to sermons in London in the 1640s and 1650s, through a variety of notes kept by pious Puritans, broadly sympathetic to the parliament's cause, including the artisan Nehemiah Wallington, John and Katherine Gell from the provincial gentry and John Harper, a city fishmonger. For these hearers, sermon note-taking had enduring purposes, for reflection, meditation and discussion, sometimes across generations; recording the immediate political context or the polemical arguments of the fast sermons was not necessarily their priority. Hearers’ notebooks place the fast sermons within a broader context of attendance at more ‘routine’ pastoral and didactic preaching in London parishes, revealing also that a preacher like Stephen Marshall, best known for his dynamic sermons before the parliament, spent most of his time on less controversial series of sermons on central issues of Protestant faith. Note-taking practices suggest that too sharp a contrast between polemical and routine preaching would be misleading; the fast sermons could be apprehended in a variety of ways by conscientious Puritan hearers, while sermons with a more pastoral focus nonetheless exhibited clear signs of the tensions and dilemmas provoked by the religious conflicts of the period.
‘THE HONEST TRADESMAN’S HONOUR’: OCCUPATIONAL AND SOCIAL IDENTITY IN SEVENTEENTH-CENTURY ENGLAND
Authors: Hailwood Mark 
Published: November 2014

ABSTRACTThis paper starts from the proposition that historians of identity in the early modern period have paid insufficient attention to the significance of occupations and work. It demonstrates one possible approach to this topic by exploring the social identity of a particular occupational group – tradesmen – through a study of a particular source – printed broadside ballads. A number of important conclusions result: it argues that historians have overstated the dominance of craft-specific consciousness in the formation of early modern work-based identity (a term that is offered as a more helpful alternative to that of occupational identity), and suggests that broad-based identifiers such as ‘tradesman’ had a real purchase in contemporary discourse. It also considers the extent to which broader changes in the seventeenth-century economy – especially growing commercialisation and the increasing complexity of credit relations – affected the identity of the tradesman. Although the tension between the hard-working tradesman and the prodigal gentleman in ballad portraits suggests a growing social confidence on the part of the former, the marketplace is depicted to be as much a threat as an opportunity for tradesmen given the fragility of credit relationships. Moreover, the paper examines the gender dimensions of this occupational identity, arguing that a ‘female voice’ was central to ballad discussions of masculine ideals, and that the tradesman's patriarchal authority was generally portrayed as insecure. At its heart, the paper is an exploration of the intersection of class, gender and occupational identities in a period of economic change.
Consequences of stratospheric ozone depletion and climate change on the use of materials
Authors: Andrady A. L. , Torikai A. , Redhwi H. H. , Pandey K. K. , Gies P. 
Published: November 2014

Abstract
Materials used in the exterior of buildings and in construction are routinely exposed to solar UV radiation. Especially in the case of wood and plastic building materials, the service life is determined by their weather-induced deterioration. Any further increase in ground-level solar UV radiation, UV-B radiation in particular, will therefore reduce the outdoor service life of these products. Any increase in ambient temperature due to climate change will also have the same effect. However, the existing light-stabilizer technologies are likely to be able to mitigate the additional damaging effects due to increased solar UV radiation and maintain the outdoor lifetimes of these materials at the present levels. These mitigation choices invariably increase the lifetime cost of these products. A reliable estimate of what this additional cost might be for different products is not available at the present time. Personal exposure to UV radiation is reduced both by clothing fabrics and glass windows used in buildings and automobiles. This assessment describes how the recent technical advances in degradation and stabilization techniques impact the lifetimes of plastics and wood products routinely exposed to solar UV radiation and the protection to humans offered by materials against solar UV radiation.
Respiratory sinus arrhythmia in young men and women at different chest wall configurations
Authors: Mortola Jacopo P. , Marghescu Domnica , Siegrist-Johnstone Rosmarie 
Published: November 2014

Respiratory sinus arrhythmia (RSA) is an acceleration of heart rate during inspiration and deceleration with expiration. We asked whether or not in humans some of the volume-related information necessary for RSA originated from the chest wall. Men and women, 19–20 years old, were breathing supine. Rib cage and abdomen displacement provided an index of tidal volume (VT) and RSA was computed breath-by-breath from the peak and trough of instantaneous heart rate. First, measurements were taken during breathing at rest (protocol a, 129 male and 164 female). Then, in subgroups of the original subject population, measurements were collected for the first five breaths immediately following a brief breath-hold period (protocol b), predominantly with the rib cage or predominantly with the abdomen (protocol c), above functional residual capacity or below it (protocol d). As long as VT was constant, severe chest wall distortion (protocol c) did not modify RSA. A drop in absolute lung volume (protocol d) or an increase in VT (protocol b) respectively decreased and increased RSA. The results, globally taken, are compatible with the notion that in humans changes in lung volume are detected by lung mechanoreceptors, whereas chest wall reflexes play no role in RSA. No difference in RSA emerged between genders during resting breathing or modest breath-hold hyperventilation.
Green‐light‐enhanced super‐continuum generation in tapered photonic crystal fibre for efficient fceo detection of Yb:fibre laser frequency combs
Authors: Niu Fuzeng , Jiang Tongxiao , Lai Shunnan , Zhang Wei , Wang Aimin , Zhang Zhigang 
Published: November 2014

Green‐light‐enhanced super‐continuum generation which covers the range from 500 to 1600 nm with a strong peak at 530 nm in a tapered photonic crystal fibre with pump pulse energy as low as 280 pJ from a mode‐locked Yb:fibre laser is reported. By the f‐to‐2f self‐reference technique, a 27 dB fceo signal was detected using the frequency pair at the Yb:laser wavelength (∼1060 nm) and this green light peak. It demonstrates the feasibility and high efficiency of fceo beat detection for simplified Yb:fibre laser frequency combs.
Enhanced isolation with defected ground structure in MIMO antenna
Authors: Anitha R. , Sarin V.P. , Mohanan P. , Vasudevan K. 
Published: November 2014

A defected ground structure (DGS) for improving isolation between four ports in a collocated multiple‐input–multiple‐output (MIMO) antenna is proposed. Isolation improvement by 7 dB is achieved by reducing surface waves within the dielectric substrate. Mutual coupling values as low as −25 dB are obtained along both the E‐ and H‐planes. The MIMO antenna includes a square patch antenna surrounded by a square ring patch antenna with the DGS etched in the form of a square ring. The DGS effectively suppresses the cross‐polarisation levels for all radiating modes. The design and effectiveness of the DGS in improving isolation for a fabricated 4‐port antenna are discussed.
Physical origin of gate voltage‐dependent drain–source capacitance in short‐channel MOSFETs
Authors: Hong Seoyoung , Lee Seonghearn 
Published: November 2014

For the first time, it is revealed that the physical origin of the gate–source voltage (Vgs)‐dependent drain–source capacitance in short‐channel metal–oxide semiconductor field‐effect transistors (MOSFETs) comes from the depletion capacitance components between the drain and channel end in the saturation region. On the basis of this origin, it is newly found that the Vgs‐dependent channel resistance should be connected in series with the drain–source capacitance to model the high‐frequency (HF) response of the intrinsic output capacitance. The accuracy of an improved MOSFET model, including the channel resistance, is validated by observing the excellent agreement with the measured S‐parameters in the wide range of Vgs up to 40 GHz.
Degradation of mouse locomotor pattern in the absence of proprioceptive sensory feedback
Authors: Akay Turgay , Tourtellotte Warren G. , Arber Silvia , Jessell Thomas M. 
Published: November 2014

Significance
Terrestrial locomotion is thought to be generated by the actions of a circuit of interconnected interneurons (central pattern generator) in the spinal cord that drive the patterned activity of pools of motor neurons, causing sequential contraction of dozens of leg muscles. Sensory feedback exerts a strong modulatory influence on this pattern; nevertheless, it remains unclear whether sensory feedback also plays a role in the generation of the normal locomotor pattern. Through the use of a combination of electrophysiology, behavior, and mouse genetics, we provide evidence that the absence of proprioceptive sensory feedback degrades locomotor pattern, indicating that proprioceptive feedback is required for the construction of locomotor pattern.
What handedness and angles between helices has the studied three-helical protein domain?
Authors: Pereyaslavets Leonid B. , Glyakina Anna V. , Dovidchenko Nikita V. , Sokolovskiy Igor V. , Galzitskaya Oxana V. 
Published: November 2014

Abstract
Summary: We have created a new server FoldHandedness. Using this server it is possible: (i) to define the regions of helices from two issues (from the PDB file and using the last version of the DSSP program), (ii) to determine the handedness for any chosen three helices and (iii) to calculate the angle and sign between the chosen pairs of the helices for large proteins and complexes of proteins with DNA or RNA.
Availability and implementation: The FoldHandedness server is available for users at http://bioinfo.protres.ru/foldhandedness
Contact: ogalzit@vega.protres.ru
MUSCLE: automated multi-objective evolutionary optimization of targeted LC-MS/MS analysis
Authors: Bradbury James , Genta-Jouve Grégory , Allwood J. William , Dunn Warwick B. , Goodacre Royston , Knowles Joshua D. , He Shan , Viant Mark R. 
Published: November 2014

Abstract
Summary: Developing liquid chromatography tandem mass spectrometry (LC-MS/MS) analyses of (bio)chemicals is both time consuming and challenging, largely because of the large number of LC and MS instrument parameters that need to be optimized. This bottleneck significantly impedes our ability to establish new (bio)analytical methods in fields such as pharmacology, metabolomics and pesticide research. We report the development of a multi-platform, user-friendly software tool MUSCLE (multi-platform unbiased optimization of spectrometry via closed-loop experimentation) for the robust and fully automated multi-objective optimization of targeted LC-MS/MS analysis. MUSCLE shortened the analysis times and increased the analytical sensitivities of targeted metabolite analysis, which was demonstrated on two different manufacturer’s LC-MS/MS instruments.
Availability and implementation: Available at http://www.muscleproject.org.
Contact: info@muscleproject.org
Supplementary information: Supplementary data are available at Bioinformatics online.
EVpedia: a community web portal for extracellular vesicles research
Authors: Kim Dae-Kyum , Lee Jaewook , Kim Sae Rom , Choi Dong-Sic , Yoon Yae Jin , Kim Ji Hyun , Go Gyeongyun , Nhung Dinh , Hong Kahye , Jang Su Chul , Kim Si-Hyun , Park Kyong-Su , Kim Oh Youn , Park Hyun Taek , Seo Ji Hye , Aikawa Elena , Baj-Krzyworzeka Monika , van Balkom Bas W. M. , Belting Mattias , Blanc Lionel , Bond Vincent , Bongiovanni Antonella , Borràs Francesc E. , Buée Luc , Buzás Edit I. , Cheng Lesley , Clayton Aled , Cocucci Emanuele , Dela Cruz Charles S. , Desiderio Dominic M. , Di Vizio Dolores , Ekström Karin , Falcon-Perez Juan M. , Gardiner Chris , Giebel Bernd , Greening David W. , Gross Julia Christina , Gupta Dwijendra , Hendrix An , Hill Andrew F. , Hill Michelle M. , Nolte-'t Hoen Esther , Hwang Do Won , Inal Jameel , Jagannadham Medicharla V. , Jayachandran Muthuvel , Jee Young-Koo , Jørgensen Malene , Kim Kwang Pyo , Kim Yoon-Keun , Kislinger Thomas , Lässer Cecilia , Lee Dong Soo , Lee Hakmo , van Leeuwen Johannes , Lener Thomas , Liu Ming-Lin , Lötvall Jan , Marcilla Antonio , Mathivanan Suresh , Möller Andreas , Morhayim Jess , Mullier François , Nazarenko Irina , Nieuwland Rienk , Nunes Diana N. , Pang Ken , Park Jaesung , Patel Tushar , Pocsfalvi Gabriella , del Portillo Hernando , Putz Ulrich , Ramirez Marcel I. , Rodrigues Marcio L. , Roh Tae-Young , Royo Felix , Sahoo Susmita , Schiffelers Raymond , Sharma Shivani , Siljander Pia , Simpson Richard J. , Soekmadji Carolina , Stahl Philip , Stensballe Allan , Stępień Ewa , Tahara Hidetoshi , Trummer Arne , Valadi Hadi , Vella Laura J. , Wai Sun Nyunt , Witwer Kenneth , Yáñez-Mó María , Youn Hyewon , Zeidler Reinhard , Gho Yong Song 
Published: November 2014

Abstract
Motivation: Extracellular vesicles (EVs) are spherical bilayered proteolipids, harboring various bioactive molecules. Due to the complexity of the vesicular nomenclatures and components, online searches for EV-related publications and vesicular components are currently challenging.
Results: We present an improved version of EVpedia, a public database for EVs research. This community web portal contains a database of publications and vesicular components, identification of orthologous vesicular components, bioinformatic tools and a personalized function. EVpedia includes 6879 publications, 172 080 vesicular components from 263 high-throughput datasets, and has been accessed more than 65 000 times from more than 750 cities. In addition, about 350 members from 73 international research groups have participated in developing EVpedia. This free web-based database might serve as a useful resource to stimulate the emerging field of EV research.
Availability and implementation: The web site was implemented in PHP, Java, MySQL and Apache, and is freely available at http://evpedia.info.
Contact: ysgho@postech.ac.kr
A DEK Domain-Containing Protein Modulates Chromatin Structure and Function inArabidopsis
Authors: Waidmann Sascha , Kusenda Branislav , Mayerhofer Juliane , Mechtler Karl , Jonak Claudia 
Published: November 2014

AbstractChromatin is a major determinant in the regulation of virtually all DNA-dependent processes. Chromatin architectural proteins interact with nucleosomes to modulate chromatin accessibility and higher-order chromatin structure. The evolutionarily conserved DEK domain-containing protein is implicated in important chromatin-related processes in animals, but little is known about its DNA targets and protein interaction partners. In plants, the role of DEK has remained elusive. In this work, we identified DEK3 as a chromatin-associated protein in Arabidopsis thaliana. DEK3 specifically binds histones H3 and H4. Purification of other proteins associated with nuclear DEK3 also established DNA topoisomerase 1α and proteins of the cohesion complex as in vivo interaction partners. Genome-wide mapping of DEK3 binding sites by chromatin immunoprecipitation followed by deep sequencing revealed enrichment of DEK3 at protein-coding genes throughout the genome. Using DEK3 knockout and overexpressor lines, we show that DEK3 affects nucleosome occupancy and chromatin accessibility and modulates the expression of DEK3 target genes. Furthermore, functional levels of DEK3 are crucial for stress tolerance. Overall, data indicate that DEK3 contributes to modulation of Arabidopsis chromatin structure and function.
Piezo‐composite actuated control surface system for flying vehicle
Authors: Hoon Park Ki , Soo Yoon Bum , Trung Nguyen Ngoc , Seo Goo Nam , Sam Kang Tae , Joon Yoon Kwang 
Published: November 2014

PurposeThe purpose of this paper is to develop lightweight actuators in order to replace conventional hydraulic/pneumatic actuators and to apply the actuation system to a small flying vehicle.Design/methodology/approachA new type of control surface using a piezo‐composite actuator for a small flying vehicle has been designed and manufactured. The piezo‐composite actuator is composed of a piezoelectric ceramic layer, a carbon/epoxy layer and glass/epoxy layers. Through this, the miniaturization and weight reduction of the actuation systems for flying vehicle can be achieved. A simple model of the control surface has been manufactured and evaluated through experiments.FindingsThe performance test results showed that the developed actuator can produce stable angle of attack independent of the applied loading. A radio controller for the actuator was developed to control the motions wirelessly. It was found that the piezo‐composite actuator and its integrated controller system have a possibility to be used not only as a small flying vehicle but also as a control surface actuator of a small unmanned flying robot through the miniaturization of power supply and control system.Originality/valueThe paper describes the procedures of designing and manufacturing smart structure application of the piezo‐composite actuator with performance evaluation and comparison method. It is expected that piezo‐composite actuator can be used as a small flying vehicle control surface actuator through the miniaturization of power supply and control system with the use of the integrated radio controller MIPAD.
Factors influencing auditor change: evidence from Malaysia
Authors: Nazatul Faiza Syed Mustapha Nazri Sharifah , Smith Malcolm , Ismail Zubaidah 
Published: November 2014

PurposeThe purpose of this paper is to examine two factors which influence auditor change: audit and client firms’ characteristics, for Malaysian listed companies. Given the costs involved, it is important to understand the reasons why companies change their auditor and choose a particular level of audit assurance.Design/methodology/approachThis study evaluates the effects of various independent variables on auditor change behaviour and the sensitivity of results to alternative period measurement by using logistic regression analysis.FindingsAn examination of 400 companies listed on the Bursa Malaysia (formerly known as Kuala Lumpur Stock Exchange‐KLSE) over a period of 18 years reveals auditor change to be significantly influenced by client firm's characteristics, notably changes in management, size of the client firm, complexity, and client's firm growth, lending support to the findings of previous survey studies.Research limitations/implicationsIn the cause of brevity, a number of potentially important variables, that might enhance an understanding of auditor change behaviour in Malaysia, were not incorporated in the regression models, and might be considered in future studies.Originality/valueThe results presented in the paper have important implications for both the auditing profession and regulators in Malaysia.