bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of n-3 unsaturated fatty acid diet on C-reactive protein and erythrocyte sedimentation rate in the anti-inflammatory effect of rheumatoid arthritis: A meta-analysis
Authors: Ding C.B. , Wang Y.L. , Deng J.M. , Zhang K.X. , Feng X.J. , Zhang Z.H. , Gao M. 
Published: August 2024

AbstractThe work was carried out to explore whether the anti-inflammatory effect of n-3 unsaturated fatty acids on patients with rheumatoid arthritis is related to the levels of inflammatory markers CRP and ESR. Studies on the treatment of rheumatoid arthritis with n-3 unsaturated fatty acid diet therapy and the outcome index containing CRP and/or ESR were included, and studies on the subjects suffering from other diseases affecting the outcome index were excluded. PubMed, Web of Science, EMBASE and Google Scholar were systematically searched, and all studies published from the establishment of the library to 2024 were collected. The Cochrane Bias Risk Assessment tool was used to evaluate the quality of the included studies. Data analysis was performed using Stata 16.0 software. Seven studies were included in this analysis. A total of 399 subjects were studied to explore the effect of an n-3 unsaturated fatty acid diet on rheumatoid arthritis. The results showed that there was no significant difference in CRP (Hedges's g = 0.06, 95% CI: −0.48–0.37, P = 0.79) and ESR (Hedges's g = −0.14, 95% CI: −0.61–0.33, P = 0.55) between the intervention and control groups. The results of this study showed that the anti-inflammatory effect of unsaturated fatty acids on rheumatoid arthritis was not correlated with CRP and ESR levels. Due to the small number of included studies, more high-quality studies are still needed to confirm this.
Robust energy management system for electric vehicle
Authors: Challoob Ali Falih , Bin Rahmat Nur Azzammudin , A/L Ramachandaramurthy Vigna K. , Humaidi Amjad J. 
Published: August 2024

AbstractThe Energy Management System (EMS) is critical for electric vehicle (EV) in order to optimize energy consumption, improve efficiency, and enhance vehicle performance. The EMS provides the optimization of energy distribution among various vehicle components, reduces energy losses and maximizes the vehicle's efficacy. The EMS reduces battery stress to prevent excessive charging and discharging cycles; thereby, decreases the necessity for premature battery replacement which, in turn, contributes to the battery's life time. The goal of this research is to develop robust control technique to maximize the use of energy storage systems, renewable energy sources and the bidirectional power flow associated with EVs. The proposed robust control approach is based on combination of flatness theory with artificial neural network. The controller is responsible for maintaining the voltage DC bus stabilized and enhancing the quality of the power fed to the EV side. The performance of controlled EMS is verified via computer simulation within MATLAB/SIMULINK environment. As compared to classical proportional-integral (PI) control, the computer results show the proposed controller (FEMS-ANN) gives higher power quality of EV, lower overshot level in the DC voltage, faster response to abnormal conditions, and less steady state error.
Regenerative Role of Lrig1 + Cells in Kidney Repair
Authors: Lee Yura , Kim Kwang H. , Park Jihwan , Kang Hyun Mi , Kim Sung-Hee , Jeong Haengdueng , Lee Buhyun , Lee Nakyum , Cho Yejin , Kim Gyeong Dae , Yu Seyoung , Gee Heon Yung , Bok Jinwoong , Hamilton Maxwell S. , Gewin Leslie , Aronow Bruce J. , Lim Kyung-Min , Coffey Robert J. , Nam Ki Taek 
Published: August 2024

Key Points

Lrig1

+
cells exist long term during kidney homeostasis and become activated upon injury, contributing to regeneration.
Lrig1

+
cells and their progeny emerge during tubulogenesis and contribute to proximal tubule and inner medullary collecting duct development.
Lrig1

+
cells expand and differentiate into a mature nephron lineage in response to AKI to repair the proximal tubule.

Background
In response to severe kidney injury, the kidney epithelium displays remarkable regenerative capabilities driven by adaptable resident epithelial cells. To date, it has been widely considered that the adult kidney lacks multipotent stem cells; thus, the cellular lineages responsible for repairing proximal tubule damage are incompletely understood. Leucine-rich repeats and immunoglobulin-like domain protein 1–expressing cells (Lrig1
+ cells) have been identified as a long-lived cell in various tissues that can induce epithelial tissue repair. Therefore, we hypothesized that Lrig1
+ cells participate in kidney development and tissue regeneration.

Methods
We investigated the role of Lrig1

+
cells in kidney injury using mouse models. The localization of Lrig1

+
cells in the kidney was examined throughout mouse development. The function of Lrig1

+
progeny cells in AKI repair was examined in vivo using a tamoxifen-inducible Lrig1-specific Cre recombinase-based lineage tracing in three different kidney injury mouse models. In addition, we conducted single-cell RNA sequencing to characterize the transcriptional signature of Lrig1

+
cells and trace their progeny.

Results

Lrig1
+ cells were present during kidney development and contributed to formation of the proximal tubule and collecting duct structures in mature mouse kidneys. In three-dimensional culture, single Lrig1
+ cells demonstrated long-lasting propagation and differentiated into the proximal tubule and collecting duct lineages. These Lrig1
+ proximal tubule cells highly expressed progenitor-like and quiescence-related genes, giving rise to a novel cluster of cells with regenerative potential in adult kidneys. Moreover, these long-lived Lrig1
+ cells expanded and repaired damaged proximal tubule in response to three types of AKIs in mice.

Conclusions
These findings highlight the critical role of Lrig1
+ cells in kidney regeneration.
Tomografía axial computarizada y resonancia magnética para la elaboración de un atlas de anatomía segmentaria a partir de criosecciones axiales del perro
Authors: Aguinaga Héctor F. , Rivera Posada Jairo A. , Tamayo Arango Lynda , Tobón R. Mauricio , Osorno Ch. Roberto C. 
Published: August 2024

Resumen
El artículo describe el método para la elaboración de un atlas digital de la anatomía segmentaria del perro, por crioseccionamiento, mediante las técnicas de tomografía axial computarizada y de resonancia magnética. Dicho atlas es una herramienta didáctica y de apoyo diagnóstico para estudiantes de pre y posgrado, y para los profesionales del área. Para el procedimiento se utilizó una hembra canina, adulta, criolla, de color negro, clínicamente sana, de aproximadamente 4 años de edad, 22 kg de peso y de tamaño mediano (50 cm de altura a la cruz). Los exámenes imagenológicos de tomografía axial computarizada y de resonancia magnética se llevaron a cabo en el Hospital San Vicente de Paúl y en el Instituto de Alta Tecnología Médica de Antioquia (IATM), respectivamente. Se obtuvieron imágenes segmentarias de la estructura corporal total del animal en sus planos frontal, sagital y transverso o axial. Con base en estas imágnes se compararon las estructuras anatómicas con los cortes del cadáver del animal. Además de la utilidad para el atlas digital, las imágenes formarán parte de una base de datos a utilizar en el laboratorio de anatomía animal de la Universidad de Antioquia.
Summary
This article describes the process of creation of a digital atlas of canine anatomy by criosectioning with computed tomography and magnetic resonance. The atlas is intended to be of help for students and practitioners. A medium size, adult, healthy creole, black colored bitch was used, weighing 22 Kg. Computed tomography and magnetic resonance were performed at the San Vicente de Paul Hospital and at the Instituto de Alta Tecnología Médica de Antioquia (IATM), respectively. Segmentary images (frontal, sagital and transverse) of the complete body were obtained and analyzed by comparison with real cuts of the dog's body. Besides its use for the atlas these images are available in the animal anatomy laboratory at the Universidad de Antioquia.
Influencia de la inclusión del efecto materno en la estimación de parámetros genéticos del peso al destete en un hato de ganado de carne
Authors: Quintero Juan C. , Triana Juan G. , Quijano Jorge H. , Arboleda Elkin 
Published: August 2024

Resumen
En el presente trabajo se estimaron componentes de (co)varianza y parámetros genéticos para la característica peso al destete en animales de las razas brahman y cebú comercial. El objetivo general fue estimar y comparar los parámetros genéticos incluyendo o no el efecto genético materno por medio del Modelo Animal, usando el programa MTDFREML. Se consideraron cinco modelos que incluyeron como efectos fijos el grupo genético materno, el número de partos y el grupo contemporáneo, y como aleatorios los efectos genéticos directos y maternos y los efectos del ambiente permanente materno, además del efecto del error residual. Los coeficientes de heredabilidad directa fueron de medios a bajos (h2 a, 0.10 a 0.29) en todos los modelos. Los modelos que incluyeron el efecto genético materno presentaron valores de heredabilidad materna bajos (h2 m, 0.07 a 0.17). Las correlaciones genéticas entre los efectos directo y materno fueron de baja magnitud y negativas (-0.18 y -0.29). Se compararon los modelos entre sí realizando la prueba de máxima verosimilitud (-2LogL) a través de la prueba de ji cuadrado, obteniéndose como resultado que el mejor modelo fue el número 5 (Y = Xβ + Z1a + Z3m + Z2ep + e), el cual tuvo en cuenta todos los efectos.
Summary
The component of (co)variance and genetic parameters for weaning weight trait in animals of pure (Brahman) or crossbreed (Zebu cattle) breeds were estimated, with the aim to estimate and to compare the genetic parameters and genetic value with or without including the maternal genetic effects by mean of Animal model, using MTDFREML program. Five models were considered including 1) the maternal genetic group, 2) calving, and 3) contemporary group as fixed effects, 4) direct and maternal genetic effects and 5) maternal permanent environmental effects, as random effects, and finally the residual error effect. Direct heritability coefficients varied form median to low (h2a, 0.10 to 0.29) in all models. Models that included the maternal genetic effect presented the lowest values of maternal heritability (h2m, 0.07 to 0.17). The genetic correlations between direct and maternal effects were negative and with low magnitude (-0.18 and -0.29). The models were compared between each other using the Maximum Likelihood method (- 2 log L) based on a X2 test, and it gave as result that the best model was the five one (Y = Xb + Z1a + Z3m + Z2ep + e) which included all effects.
Uso del análisis de componentes principales para construir un índice tipo producción en ganado Romosinuano (Bos taurus)
Authors: Ruales España Fredy R. , Manrique Perdomo Carlos 
Published: August 2024

Resumen
En este trabajo se presente la metodología de Análisis de Componentes Principales (ACP) y su aplicación en la construcción de un Índice de Selección (IS) en ganado criollo Romosinuano. Para ello, se utilizó la base de datos de la Asociación de Criadores de ganado Romosinuano de Colombia (Asoromo) correspondiente a 5825 registros de peso en báscula a 30 meses de edad y 31 características bovinométricas de 184 toros y sus progenies nacidos entre 1981 y 1993, en 17 fincas. Se editó la base de datos para que todos los animales tuviesen información en todas las variables para obtener las correlaciones entre ellas, obteniendo una base completa de 1562 registros y 20 características correspondientes a las progenies de 121 toros. Se realizó un ACP sobre el peso y las medidas bovinométricas en estudio para seleccionar aquellas variables que aportaron los mayores componentes principales de variación y se asociaron a estos resultados los valores de los parámetros genéticos, obteniendo ocho medidas bovinométricas asociadas con el peso. Se construyó un IS con estas características, con lo cual se obtuvo mayor progreso genético que la selección por peso, lo que justifica la utilización del ACP para generar un índice basado en medidas bovinométricas correlacionadas con el peso de los animales.
Summary
In this work the Principal Components Analysis (PCA) and its application in constructing a Selection Index (SI) for Romosinuano cattle is shown. The database of the Colombian Romosinuano Breeders Association was used, corresponding to 5825 records of body weight at 30 months and 31 bovinometrics traits of a progeny of 184 sires, born between 1981 and 1993 in 17 herds. The data base was edited for including only animals that fit all variables needed to get correlations, which resulted in a data base of 1562 records from progenies belonging to 121 sires. A PCA was applied to body weight and bovinometrics traits with the aim to select those that gave the maximum principal component variation and that were associated with genetic parameters, which results in 8 bovinometric traits associated to body weight. A SI was constructed with these traits, resulting in a greater genetic progress than that obtained for selection according to body weight alone, justifying the use of PCA to generate a SI based on morphometric traits associated to body weight.
Comparación de las propiedades de osteoconducción y osteointegración de una hidroxiapatita reabsorbible comercial con una hidroxiapatita reabsorbible sintetizada
Authors: Jaramillo Carlos D. , Rivera Posada Jairo A. , Echavarría Alejandro , O¨byrne Johan , Congote Diego , Restrepo Luis F. 
Published: August 2024

Summary
In the following article the effects of two types of hydroxiapatites on bone synthesis and properties were evaluated. One of them (OseoU) was synthesized at two different temperatures to compare it to a commercial mixture of hydroxiapatite (Osteogen®) commonly used in several surgical procedures in which loss of bone tissue is present. The synthesis was carried out in the laboratories of the Universidad de Antioquia by precipitating the mixture of calcium nitrate and ammonium phosphate. The final products and the commercial hydroxiapatite were characterized by sweeper electronic microscopy (SEM), X ray diffraction (XRD), Fourier transformed infrared spectroscopy (FTIR), and energy dispersed spectrometry (EDS). The properties of osteoconduction and osteointegration were measured according to the capacity of the products to induce the differentiation of local cells into bone forming cells. Such characteristics were evaluated in hydroxiapatite implants in 70 New Zealand breed rabbits distributed in seven groups, ten rabbits in each group, which were evaluated at days 7, 14, 21, 28, 42, 60 and 90 after the surgical procedure. The results demonstrated that the hydroxiapatites synthesized in the laboratories of the Universidad de Antioquia and the commercial hydroxiapatite showed similar characteristics in terms of the crystal structure, chemical composition and absorption properties with slight morphological differences in particle shape and size. Using variance analysis, no meaningful statistical differences were found between the histopathological variables evaluated in the several hydroxiapatite groups (p>0.05), indicating that results obtained with both the OseoU and the commercial hydroxiapatite equally affected bone synthesis and properties.
Virus de Fiebre Aftosa: Una aproximación al estado del arte
Authors: Ruiz Sáenz Julián , Jaime Jairo , Vera Víctor 
Published: August 2024

Summary Foot-and-Mouth disease (FMD) is a viral disease caused by a prototype member of the Picornaviridae family. Although the disease has been described for more than 5 centuries, it remains one of the major health and economic barriers for cattle and swine import and export. Since 75% of the national cattle herd is FMD free, it is necessary to provide an updated literature review of the disease. Updated information of FMD will assist in the decision making of the need and use of vaccines, especially at the time when the country is declared free of FMD.
Aktivitas Fisik dengan Status Gizi Remaja di SMP Negeri 25 Surabaya
Authors: Rochmah Aulia , Nadhiroh Siti Rahayu 
Published: August 2024

Latar Belakang: Aktivitas fisik ialah suatu tindakan yang dilakukan oleh individu mulai dari bangun tidur sampai kembali istirahat. Aktivitas Fisik merupakan suatu hal yang sangat penting supaya dapat menjaga kesehatan tubuh dan berat badan ideal. Peningkatan tingkat hidup dan kemajuan teknologi telah memicu perubahan dalam cara hidup atau pola kebiaasan hidup. Adanya budaya kekinian dengan dukungan inovasi terkini dapat menyebabkan berkurangnya menurunnya aktivitas fisik. Kurang aktivitas fisik dapat memicu resiko peningkatan nilai IMT (Indeks Massa Tubuh). Untuk memastikan bahwa remaja mencapai berat badan yang ideal dan mempertahankan kondisi kesehatan fisik, sangat penting bagi mereka untuk meningkatkan tingkat aktivitas fisik.
Tujuan: Penelitian ini dilakukan dengan tujuan untuk megetahui hubungan aktivitas fisik dengan status gizi remaja di SMP Negeri 25 Surabaya
Metode: Jenis penelitian ini bersifat observasional dengan desain studi review cross-sectional. Sampel penelitian ini sebanyak 80 responden. Analisis data pada penelitian ini terdiri dari univariat dan bivariat dengan menggunakan Chi-Square
Hasil: Hasil penelitian ini menunjukkan kalau 42,5% siswa berstatus gizi normal dan 77,5% siswa melakukan aktivitas fisik ringan. Berdasarkan analisis bivariat diketahui terdapat hubungan yang signifikan antara aktivitas fisik dengan status gizi remaja di SMP Negeri 25 Surabaya (p-value = 0,008).
Kesimpulan: Adanya hubungan yang signifikan antara aktivitas fisik dengan status gizi remaja di SMP Negeri 25 Surabaya. Disarankan agar melakukan pengukuran dan penimbangan berat badan setiap minggu oleh petugas yang terlatih untuk dapat memantau status gizi masing-masing dan melakukan aktivitas fisik secara rutin.
Determinants of Wealth Related Inequalities in Full Childhood Vaccination in Nepal: A Decomposition Analysis Using Nepal Demographic and Health Survey (NDHS) 2022
Authors: Singh Barun Kumar , Khatri Resham B 
Published: August 2024

Abstract

Background Over the past two decades, child health indicators in Nepal have improved significantly at the national level. Yet, this progress hasn't been uniform across various population subsets. This study identified the determinants associated with childhood full vaccination, assessed wealth-related inequalities, and delved into the key factors driving this inequality.Methods Data for this study were taken from the most recent nationally representative Nepal Demographic and Health Survey 2022. A total of 959 children aged 12–23 months who had received routine childhood vaccinations as per the national immunisation program were considered for analysis. Binary logistic regression models were conducted to identify the associated factors with outcome variable (uptake of full vaccination). The concentration curve and Erreygers normalized concentration index were used to assess inequality in full vaccination. Household wealth quintile index scores were used to measure wealth-related inequality in households. Decomposition analysis was conducted to identify determinants explaining socio-economic inequality in the uptake of childhood vaccination.Results The coverage of full vaccination among children was 79.8% at national level. Several factors, including maternal health service utilisation variables (e.g., antenatal care, institutional delivery), financial challenges related to visiting health facilities, and mothers' awareness of health mother group meetings within their ward, were associated with the uptake of full vaccination coverage among children. The concentration curve was below the line of equality, and the relative Erreygers normalized concentration index was 0.090, indicating that full vaccination was disproportionately higher among children from wealthy groups. The decomposition analysis identified institutional delivery (20.21%), the money needed to visit health facilities (14.25%), maternal education (16.79%), maternal age (8.53%), and caste (3.03%) were important contributors to wealth related inequalities in childhood full vaccination uptake.Conclusions There was notable socioeconomic inequality in full vaccine uptake among children in Nepal. Multisectoral actions involving responsible stakeholders are pivotal in reducing the inequalities, including promoting access to maternal health services and improving educational attainment among mothers from socioeconomically disadvantaged communities.
Pediatric Endogenous Endophthalmitis: Clinical features and treatment outcomes
Authors: Padhy Srikanta Kumar , Nanda Ridham , Das Taraprasad , Padhy Tapas , Panda Krushna Gopal 
Published: August 2024

Abstract

Objectives: Analyse the demographic, clinical-microbiological profile, and treatment outcome of pediatric patients with endogenous endophthalmitis.
Methodology: We conducted a retrospective analysis of electronic medical records covering eight years from 2013 to 2020 at a tertiary eye care centre in India, focusing on patients of age <18 years diagnosed with endogenous endophthalmitis. Data extraction included demographic variables, clinical presentations, microbiological analyses, therapeutic interventions, and visual outcomes.
Results: The analysis included 48 patients with an average age of 5.4 ± 4.98 years and an equal gender ratio. In this period, 5% of all endophthalmitis (48 of 961) and 20.8% of pediatric endophthalmitis (48 of 231) were treated. Common symptoms included redness (62.5%), reduced vision (20.8%), leucocoria (27.08%), pain (22.91%), and watering/discharge (29.16%). Clinical signs included vitritis (89.58%) and anterior chamber exudates/hypopyon (47.91%). Vitreous culture positivity was 54.05%; common isolates were gram-negative bacilli (35%), gram-positive cocci (25%), gram-positive bacilli and fungus (20% each). Systemic infection was present in 72.9% of patients; respiratory tract infection was most common (54.2%). All eyes received intravitreal antibiotic injections, and 28 (75.7%) received vitrectomy. Children under 5 with systemic illness had a worse visual prognosis. Unfavourable outcomes were associated with gram-positive bacilli and fungal infection. Approximately 45% of eyes worsened to phthisis.
Conclusions: Any redness in a child with systemic infection warrants prompt ophthalmic evaluation. Children under 5 with systemic illness are associated with a worse visual prognosis. Unfavourable outcomes are linked to gram-positive bacilli and fungal infection.