bluuebunny/crossref_metadata_2025_split huggingface dataset:
1718 – Depression And Risk Development Of Acute Cardiovascular Diseases In Female Population Aged 25–64 In Russia
Authors: Gafarov V. , Panov D. , Gromova E. , Gagulin I. , Gafarova A. 
Published: July 2013

The aimTo explore the effect of depression (D) on relative risk of myocardial infarction (MI) and stroke and its relation with awareness and attitude towards the health in female population of 25–64 years in Russia.Material and methodsUnder the third screening of the WHO “MONICA-psychosocial” (MOPSY) program random representative sample of women aged 25–64 years (n=870) were surveyed in Novosibirsk. D was measured at the baseline examination by means of test “MOPSY”. From 1995 to 2010 women were followed for 16 years for the incidence of MI and stroke.ResultsThe prevalence of D in women aged 25–64 years was 55.2%. With growth of D levels positive self-rated health reduced and almost 100% of those women have health complaints. Women with major D significantly extended negative behavioral habits: smoking and unsuccessful attempts to give it up, low physical activity, they are less likely to follow a diet. Major D associated with high job strain and family stress. Risk of MI development in women with D during 16 years of study was higher in 2.53 times (95%CI=1.26-24.34; p< 0.05), risk of stroke was higher in 4.63 times (95%CI=1.03-20.89; p< 0.05 MI and stroke rates were more likely in married women having D with average educational level who being in both “managers” and “physical labor” social classes.ConclusionsThe prevalence of D in women aged 25–64 years more than 50%. Women with D had 2.53-fold risk of MI and 4.63-fold risk of stroke over 16 years of follow-up.
1720 – From Psychosis To Remission Through Artistic Expression
Authors: Derganc M. , Savs A.P. , Care K. 
Published: July 2013

IntroductionGroup music/art therapy in patients with schizophrenia may not contribute to the treatment outcome but it certainly offers an opportunity to monitor patient's progress during psychiatric treatment. In our case we followed the patient's improvement through ten drawings.Case reportA 24-year-old female psychology student was admitted to our hospital for the first time. She presented with unusual posturing, mannerisms, disorganized speech, auditory hallucinations, and paranoid delusions. According to her mother, the symptoms started about two years prior to the hospitalization. She was unsuccessfully treated with olanzapine at maximum dose. Additional treatment with a maximum dose of amisulpride also proved unsuccessful. After switching her to clozapine and aripiprazole her behavior normalized and the psychotic symptoms subsided. Because of epileptic seizures as a side effect of clozapine treatment she was given valproic acid. She achieved solid remission and was transferred to the day hospital. As an inpatient she attended group music/art therapy sessions once a week. At the beginning her drawings were abstract, disorganized and perseverative. As her mental status improved, her drawings became more and more realistic.ConclusionWhile it is difficult to imagine the way someone with a mental illness perceives the world, drawings produced by the mentally ill offer a hint of this experience. In itself, realistic expression is not ’better’ than abstraction; moreover, it could be ventured that in her early drawings our patient was more responsive to musical stimuli than later when her regaining control produced more organized but also more schematic and stereotypical drawings.
1721 – Expressed Emotion In a Mixed Sample Of Psychiatric, Oncological And Obese Patients
Authors: Gili S. , Gattoni E. , Porro M. , Zeppegno P. , Gramaglia C. 
Published: July 2013

IntroductionExpressed Emotion (EE) reflects the “emotional temperature” of a family. High EE and low EE families can be identified. The degree of family EE correlates with patients’ outcome, being a high family EE predictive of a greater likelihood of relapse, an increased need for care and inpatient treatment.ObjectivesFirstly, to evaluate EE, life events and anxiety in a mixed sample of psychiatric, oncological and obese patients recruited from the Psychiatry, Oncology and Nutrition Wards of the “Maggiore della Carità” General Hospital, Novara (Italy). Secondly, to compare these parameters among the three subgroups of patients. Furthermore, we also recruited a cohabiting relative for each patient and compared the relative's EE and EE as perceived by patients.Methods112 patients attending the Psychiatry (n=34), Nutrition (n=56) and Oncology (n=21) Wards were involved. Patients were assessed by means of the following scales: Level of Expressed Emotion (LEE) scale, Paykel Life Events scale, State Trait Anxiety Inventory 1 and 2.ResultsData collection is ongoing. Anyway, preliminary results suggest that psychiatric patients are more likely to have a longstanding diagnosis, to have received inpatient care but they are less likely to suffer from comorbid organic disorders. Consistently with current literature, obese patients get higher scores than the other subgroups of patients at EE.ConclusionsClinical implications are discussed, focusing on the need to carefully address the issue of high EE families in order to reduce the need for inpatient treatment, increase compliance and improve patients’ and relatives’ quality of life.
1728 – Association Between Duration Of Untreated Psychosis And Progression Of Brain Volume Change In Schizophrenia - The Northern Finland 1966 Birth Cohort
Authors: Jääskeläinen E. , Penttilä M. , Haapea M. , Isohanni M. , Murray G. , Jones P. , Guo J. , Nikkinen J. , Kiviniemi V. , Veijola J. , Miettunen J. 
Published: July 2013

IntroductionLong duration of untreated psychosis (DUP) has been associated to brain morphological changes in schizophrenia in cross sectional analyses. It is unclear DUP relates to brain volume change over time.AimsOur aim was to analyze the association between length of DUP and total brain volume change in schizophrenia in a general population based sample.MethodsAll members of the Northern Finland 1966 Birth Cohort (NFBC1966) known to have had psychotic illness were invited for a field study at the age 34-years (in average 10 year after onset of psychosis) and follow up nine years later at the age 43-years. DUP was assessed from medical records. The total brain volume scan interval change and the DUP information were available for 32 subjects with DSM III R schizophrenia. We analysed the correlation between length of DUP and the mean annual whole brain reduction, adjusted for age of illness onset and sex.ResultsThe mean annual whole brain volume reduction was 0.66%. The reduction was 0.76% among those with shortest DUP, 0.58% among those with median DUP, and 0.63% among those with longest DUP. There was no statistically significant correlation between DUP and annual brain volume change when adjusted for onset age and/or sex.ConclusionsWe did not find an association between long DUP and brain volume decrease in schizophrenia in 9 years follow up. Although long DUP has been associated with differences in brain volume in cross sectional analyses, the significance of DUP on brain morphology in long term is unclear.
1742 – Mood Disorder, Psychotic Symptoms And Overlooked Skin Lesions. Mrs. o.: a Single Case
Authors: Pini E. , Tremolizzo L. , Tremolizzo S. , Cerri C.G. , Bartoli F. , Apollonio I. , Ferrarese C. , Cornaggia C.M. 
Published: July 2013

Mrs. O. is a 57 years old secretary. Her past medical history is unremarkable relative to psychiatric disorders or other diseases. She came to the ER because of sudden and severe depressive symptoms, including thoughts of death. Moreover, at times she had brief episodes of confusion during which she displayed depersonalization and short periods of spatial and temporal disorientation.She was hospitalized in the psychiatric ward and underwent routine blood tests, neurological exams and a MR brain scan, without showing any significant abnormalities. Notably, she presented a maculopapular rash compatible with herpes zoster. Thirteen days later, she was feeling much better and was sent home, with an indication of a psychiatric follow-up. A week later Mrs. O. returned to the ER, since she presented a mixed episode, again with psychotic symptoms. During this second period of hospitalization, Mrs. O. presented persistent mild fever, and more apparent brief moments of spatio-temporal disorientation were noted, accompanied by psychomotor slowness. The impression of an underlying process was further confirmed and a neurological consultation was asked for again. Suspecting viral encephalitis, the patient was admitted to the neurological department and started on acyclovir, demonstrating an initial improvement of the psychiatric symptoms. The follow-up MR brain scan was normal. A suspicion of acute inflammatory demyelinating polyradiculoneuropathy (AIDP) was formulated. Thirty days later Mrs. O.’s deficits in strength were improving steadily and she was transferred to the rehabilitation ward. The psychiatric symptoms had completely receded.
1748 – Electroconvulsive Treatment In Schizophrenia: a Systematic Review
Authors: Dominici G. , Longo L. , Marconi G. , Lester D. , Serafini G. , Girardi P. , Pompili M. 
Published: July 2013

IntroductionElectroconvulsive therapy (ECT) is a medical treatment that is most effective for mood disorders.It has also been shown to be an effective form of treatment for schizophrenia. However, many unanswered questions remain regarding its role in the management of people with schizophrenia.ObjectivesEvaluate the main indications of ECT in schizophrenia patients.AimsTo investigate the efficacy of ECT in the treatment of schizophrenic patients, evaluating its effects in the short-term and the long-term, comparing ECT with pharmacotherapy, and assessing the effects of treatment and the main indications for use in patients with schizophrenia.MethodsA systematic review of the literature was conducted for ECT and schizophrenia. Forty-nine articles from peerreviewed journals were identified.ResultsThe most common indication for using ECT for schizophrenia patients was to augment pharmacotherapy, while the most common accompanying symptoms were, in order, catatonia, aggression and suicide. Catatonic patients responded significantly better to ECT than patients with any other subtype of schizophrenia. The combination of ECT with pharmacotherapy can be useful for drug-resistant patients. The use of an ECT-risperidone combination or ECT-clozapine combination in patients non-responsive to prior pharmacotherapy was found to be most effective.ConclusionsECT, combined with pharmacotherapy, may be a viable option for a selected group of people with schizophrenia. In particular, the use of ECT is recommended for drug-resistant patients, for schizophrenic patients with catatonia, aggression or suicidal behavior, and when rapid global improvement and reduction of acute symptomatology is desired.
1750 – Affect Dysregulation And Eating Disorders: a Preliminary Study On The Construct Of Alexithymia
Authors: Caslini M. , Pini E. , Bartoli F. , Bertelli S. , Zappa L.E. , Clerici M. 
Published: July 2013

IntroductionAlexithymia correlates with fundamental psychological traits of eating disorders in a complex causal model and high relapse rates which may be due to a lack of affect regulation. The literature does not reach definitive conclusions about the usefulness of this construct in the clinical field.AimsThe purpose of this preliminary study was to evaluate the presence of alexithymia and its correlation with epidemiological variables, psychological characteristics, symptom severity, and general psychopathological dimensions.Materials and methodsA sample of 125 patients with eating disorders was recruited from outpatient care for eating disorders at the San Paolo Hospital in Milan. Patients were administered the following scales: the TAS20, SCL-90 and EDI-2.Results and conclusionsThe results indicate that 38% of the sample were alexithymic, an underestimation when compared to literature; different types of ED did not differ in alexithymia scores. The TAS20 did not correlate with the epidemiological variables. Diagnoses of Axis II disorders predicted the presence of alexithymia, suggesting that it may contribute to affective dysregulation found in personality disorders. The TAS20 further correlated with EDI-2, in particular with the subscales relating to the body and the relational aspects, and with the level of general psychopathology on the SCL-90, indicating that alexithymia may be a dimension that extends across nosographies in disorders of affective dysregulation.
1753 – Capacity To Exercise Civil Rights: Serial Cases Study 5 Case Reports
Authors: Barros I. , Felix Junior S.P. 
Published: July 2013

IntroductionIn Brazil there is a great demand for evaluation of the capacity to exercise civil rights of mentally ill patients, aiming their judicial interdiction as a protective measure. In Rio de Janeiro, the Public Attorney Office counts with a seven psychiatrists team, that among other functions, will evaluate the civil capacity of individuals, giving the district attorneys a technical psychiatric background to decide whether, or not, to demand a judicial interdiction.ObjectiveAnalyze five case reports in which district attorneys have demanded a civil capacity evaluation.MethodThis is a serial cases study of five patients, where each individual was assessed. The final psychiatric diagnosis was obtained with a psychiatric evaluation of the patients, the examination of their records or relatives interview.DiscussionThe five patients, each with a different diagnosis, were assessed individually. The civil incapacity is not an absolute state, but a relative situation, and the reasons and circumstances are important elements in forensic evaluation.ConclusionsInterdiction is not always the best, or even the most convenient solution to social, economic and legal problems occasioned by the absence or loss of insight or self-determination caused by disability or mental illness. It is vital to characterize the absence or loss of sense of judgment, self-determination or volition, and it is necessary to determine that such damage would be significant to the specific conditions of the familiar and socio-economic profile of each citizen.
1754 – Psychiatric Symptoms In Patients On Methadone Maintenance Treatment
Authors: Moussas G. , Fanouraki E. , Asomatou A. , Dermatis G. , Pachi A. , Nikoviotis D. , Evmolpidi A. , Zafeiropoulos G. , Bratis D. , Tselebis A. , Giotakis K. , Malliori M. 
Published: July 2013

IntroductionThe high prevalence of psychiatric comorbidity in drug dependent individuals is well known. However, there is limited literature available regarding the comorbidity of psychiatric disorders in drug addicts on methadone maintenance treatment (MMT).AimsTo determine the comorbidity of mental disorders in patients on MMT.MethodsThe Symptom Checklist 90-Revised (SCL-90R) [1] was completed by 85 drug addicts (65 male and 20 female) on MMT. We recorded demographic data, duration of addiction, and duration of MMT.ResultsThe mean age of the sample was 42.0 ± 8.8 years old, the mean duration of substance use was 24.3 ± 8.2 years and the mean duration of MMT was 6.8 ± 4.1. The majority of participants (78.8%) were unemployed and 58.3% of them had no children. Participants scored higher on the depression, paranoid ideation, anxiety, hostility, somatization, interpersonal sensitivity and psychoticism SCL-90R sub-scales, with average scores >1 [2]. On the contrary, lower scores were recorded in the obsessive-compulsive and phobic anxiety sub-scales. The percentage of participants that reported abnormal scores for each sub-scale was as follows: 89.3% for depression, 83.3% for paranoid ideation, 74.7% for anxiety, 66.7% for hostility, 64.7% for somatization, 51.2% for psychoticism and 35.7% for phobic anxiety. No abnormal scores were recorded regarding obsessive-compulsive symptoms. Only 8.4% of participants did not score abnormally on any sub-scale.ConclusionsDrug-addicted patients on MMT show a high comorbidity of psychiatric disorders. In particular, the likely presence of depressive and paranoid symptoms should be taken into serious account when deciding on a therapeutic strategy.
1758 – Comparison Of The Patterns Of Antidepressant Use Among Young And Older Adults In France
Authors: Etchepare F. , Verdoux H. , Sanglier T. , André M. , Tournier M. 
Published: July 2013

IntroductionAntidepressant drugs have been found underused in the older population relative to younger adults, particularly in the USA before Medicare part D. No study assessed the antidepressant use according to age in France.ObjectiveTo compare the patterns of antidepressant use among young and older adults: treatment duration, switches, association of antidepressants, coprescription of psychotropic drugs and adherence to treatment.MethodsA historical cohort study included 27,306 young adults and 7,747 older adults, who were beneficiaries of the French national health care insurance and initiated a new antidepressant treatment over the study period. They were followed for atleast six months.ResultsMost patients received only one type of antidepressant (91.81% of young adults and 91.73% of older). The coprescription of psychotropic drugs was frequent in both groups (62.91% in young adults and 62.36% in older). The associations of antidepressant drugs were rare (1.42% in young adults and 1.50% in older). Elderly patients had a significantly longer duration of treatment than young adults (m = 135.4 days, SD = 198.6 vs m = 104.3 days, SD = 159.6; HR = 0.9; 95%CI=[0.88–0.93]; p < 0,0001). Furthermore, they had a higher probability of good adherence than young adults when treatment was initiated by a general practitioner (23.28% vs 16.02%; OR = 1.3 [1.22–1.41]), a hospital practitioner (OR = 1.76 [1.35–2.30]) or a specialist other than psychiatrist (OR = 1.85 [1.26–2.70]).ConclusionsThe use of antidepressant drugs was similar in both age groups, except for the treatment duration and adherence that were better in the older patients. This result may be attributed to the French healthcare system.
1760 – Attempted Suicide Predictive Factors: a Case Control Study
Authors: di Giacomo E. , Giampieri E. , Clerici M. 
Published: July 2013

Aim and methodsThe aim of the study is to evaluate risk factors for attempted suicide in psychiatric patients.We compared three groups: psychiatric patients who attempted suicide, patients with the same diagnosis and no history of attempted suicide and healthy controls, through the administration of the following tests: TCI, SCL-90, WHOQOL, SASS, SF 36 and IIP.The subjects were matched for sociodemographic characteristics (sex, age, level of education, field of employment and role, marital status) with a 1:1:1 ratio.ResultsWe obtained statistically significant differences between patients who attempted suicide and patient who didn’t in subscales: harm avoidance (TCI, p = 0.021) and environment area (WHOQOL, p = 0.021).We also underline we were able to discriminate healthy subjects from patients, but we didn’t obtain statistically significant differences between controls and patients who attempted suicide in the subscales egocentricity (IIP, p = 0.051), aggressiveness (IIP, p = 0.057) and self-transcendence (TCI, p = 0.255).ConclusionThese results underline the importance of caring, with preventing purpose, about personal history data such as socioeconomic status, living environment perceived safety, different tendency to inhibit own behaviors (correlated to previous suicide attempts), closure to external relations and aggressiveness.
1766 – Female Sexual Identity Disorder And Substance Use Disorder
Authors: di Giacomo E. , Clerici M. 
Published: July 2013

IntroductionSexual identity is often neglected in the analyzes of a potential patient and this represents a very bias and a potential blurring factor especially when we research about attempted suicide or substance abuse.Materials and methodsWe analyzed EBM Literature published in the last five year, and text otherwise and previously published but esteemed as important for our purpose.ResultsLesbian population (L) have a greater and huger use of illicit drug.It's necessary to add that a great part of L population uses drug by injection, thus including all the considerations about related infections (2).Epidemiologically,we can attest that 10% of bisex (B) and 8,8% of L population have an ev drug intake.It results of the greatest interest the fact that we can measure an increase in rapist's victims in the population analyzed compared to GP (64%vs44%), and in ⅓ of the cases violence occurred during childhood.Adding that homosexual population is at major risk of suicide and attempted suicide, we are obliged to wonder if there's a common pathway or a sum of risk factors leading to these conducts.ConclusionsThe evidence of a possible correlation between sexual abuse and via PTSD the conservation of victim role, as well as the development of dissociation or personality disorder might explain a deeper use of illicit drug or alcohol in this population. International researchers in the field of SUD strongly demand to analyze sexual orientation as a risk factor for SUD since the given evidence quoted above.
1769 – Psychotic Disorder And Hospitalization Through Mobile Crisis Unit
Authors: Gómez Pérez L. , Nascimento Osorio M.T. , Sabaté Gómez A. , Córcoles Martínez D. , Malagón Amor Á. , Álvaro Serón P. , Bellsolà M. , González A. , Martín López L.M. , Bulbena Vilarrasa A. 
Published: July 2013

IntroductionThe utility of Mobile Crisis Unit (MCU) and its target population has been a controversial issue and many scientific articles have been writen about it (1,2).ObjectiveThe aim of this study is to identify the demographic and clinical features of patients diagnosed with psychotic disorder who have been hospitalized and have not required hospitalization in psychiatric unit through a Mobile Crisis Unit (MCU).MethodsWe collected retrospectively demographic and clinical variables. These include psychiatric rating scales of severity: Clinical Global Impression Scale (CGI) and Psychiatric Disease Severity (GEP); of functionality as Global Assessment of Functioning Scale (GAF); the aggressive behaviour and violence scale (AVAT) and psychopathology with the Positive and Negative Syndrome Scale (PANSS) of a total of 136 patients between June 2007 and July 2010.ResultsThere have been found stadisticaly significative differences between patients who have been hospitalized versus patients who have not in the items of treatment adherence and security staff intervention (Table 1). There is a positive correlation between patients who required hospitalization and the clinical scales CGI, GEP, GAF, AVAT, SUMD, PANSS-P and PANSS-G (Table 2).ConclusionsWe can conclude that patients cared for by the Mobile Crisis Unit (MCU) that require of psychiatric hospitalization have poor adherence to previous treatment. A high frequency of cases require intervention of security staff for having a higher risk of aggressiveness at the moment of hospitalization. The presence of greater psychopathology and functionality severity in patients hospitalized through the Mobile Crisis Unit (MCU) is also considered.Variables No hospitalization Hospitalization p N%N% SexMen3354.14154.70.95CohabitationAlone1524.62533.30.27ToxicsYes14231722.70.97Psychiatric historyYes4578.95477.10.81Previous hospitalizationsYes4268.942560.12Treatment adherenceYes1431.123.5< 0,05Security staffYes11.73957.4< 0,05Chi-square