bluuebunny/crossref_metadata_2025_split huggingface dataset:
Primary to post‐depositional microbial controls on the stable and clumped isotope record of shoreline sediments at Fayetteville Green Lake
Authors: Leapaldt Hanna C. , Frantz Carie M. , Olsen‐Valdez Juliana , Snell Kathryn E. , Trower Elizabeth J. , Ingalls Miquela 
Published: July 2024

AbstractLacustrine carbonates are a powerful archive of paleoenvironmental information but are susceptible to post‐depositional alteration. Microbial metabolisms can drive such alteration by changing carbonate saturation in situ, thereby driving dissolution or precipitation. The net impact these microbial processes have on the primary δ18O, δ13C, and Δ47 values of lacustrine carbonate is not fully known. We studied the evolution of microbial community structure and the porewater and sediment geochemistry in the upper ~30 cm of sediment from two shoreline sites at Green Lake, Fayetteville, NY over 2 years of seasonal sampling. We linked seasonal and depth‐based changes of porewater carbonate chemistry to microbial community composition, in situ carbon cycling (using δ13C values of carbonate, dissolved inorganic carbon (DIC), and organic matter), and dominant allochems and facies. We interpret that microbial processes are a dominant control on carbon cycling within the sediment, affecting porewater DIC, aqueous carbon chemistry, and carbonate carbon and clumped isotope geochemistry. Across all seasons and sites, microbial organic matter remineralization lowers the δ13C of the porewater DIC. Elevated carbonate saturation states in the sediment porewaters (Ω > 3) were attributed to microbes from groups capable of sulfate reduction, which were abundant in the sediment below 5 cm depth. The nearshore carbonate sediments at Green Lake are mainly composed of microbialite intraclasts/oncoids, charophytes, larger calcite crystals, and authigenic micrite—each with a different origin. Authigenic micrite is interpreted to have precipitated in situ from the supersaturated porewaters from microbial metabolism. The stable carbon isotope values (δ13Ccarb) and clumped isotope values (Δ47) of bulk carbonate sediments from the same depth horizons and site varied depending on both the sampling season and the specific location within a site, indicating localized (μm to mm) controls on carbon and clumped isotope values. Our results suggest that biological processes are a dominant control on carbon chemistry within the sedimentary subsurface of the shorelines of Green Lake, from actively forming microbialites to pore space organic matter remineralization and micrite authigenesis. A combination of biological activity, hydrologic balance, and allochem composition of the sediments set the stable carbon, oxygen, and clumped isotope signals preserved by the Green Lake carbonate sediments.
“Entanglement” as a concept in recent research on Christian missions in the South Pacific and Africa
Authors: Tilson Kate 
Published: July 2024

AbstractThis article provides a short overview of ‘entanglement’ in recent histories of mission, examining what distinguishes it from earlier conceptualisations of cross‐cultural encounters. This article locates the emergence of the term in the social sciences and global histories of empire, and explores its current influence in studies of Christian evangelism in imperial and colonial contexts. This article shows the strengths of recent works on entanglement, while indicating some new research avenues for scholars of mission. The discussion primarily focuses on research on Africa and the South Pacific.
Consumer adoption of digital health services: A systematic literature review and research agenda
Authors: Goel Anushka , Singh Aarushi , Taneja Udita , Jain Shilpa 
Published: July 2024

AbstractDigital health services (DHSs) have revolutionized the healthcare sector to provide quality care facilities that are affordable, efficient, and universally accessible. By making patients the focus of the healthcare delivery process, these services can offer more personalized and effective health solutions and thus facilitate a more robust and resilient health ecosystem. The adoption of these services increased manifold during the COVID‐19 pandemic and gained immense attention from researchers across the globe. Despite this, there is limited knowledge about the facets of DHS adoption from the consumers' perspective. Thus, it is imperative to synthesize the extant literature to provide a holistic view of DHS adoption. This article offers an organized, retrospective view of the DHS literature, using a framework‐based systematic review approach to identify factors contributing to DHS adoption from the consumers' perspective. To do this, 63 articles from the Web of Science database over the last 23 years were systematically reviewed using two well‐known organising frameworks. The Antecedents‐Decisions‐Outcomes framework uncovers the known associations of constructs in the DHS literature. Followed by the theories‐contexts‐methods framework that offers information on the theoretical, contextual, and methodological approaches applied in the DHS research. Additionally, the article identifies the major gaps in the existing body of literature and offers a few recommendations for future investigation for researchers and practitioners in the fields of consumer behaviour, technology, and health management. The global perspective of this review has multiple ramifications that can foster a more sustainable healthcare system by giving insight into consumers' perspectives.
Cash holding by consumers: The role of the perceived characteristics of money
Authors: Acedański Jan , Maciejewski Grzegorz , Pietrucha Jacek 
Published: July 2024

AbstractThis study examined why consumers who typically pay electronically at points of sale still carry cash and explained the inertia of demand for cash by considering the additional (perceived by consumers) characteristics of cash. The research was motivated by the growing discussion on why cash, despite the increasing importance of e‐payments, remains a significant part of the demand for money. The study focused on psychological factors and consumers' perceptions of certain features of cash, which make it an attractive additional option for precautionary reasons, and therefore, explored beyond the typical discussion of money as a means of payment. The structural equation modeling based on data collected as part of a survey of Polish consumers was used to verify the hypotheses. It was revealed that cash becomes a reserve solution for consumers, which is kept “just in case” to expand the scope of personal freedom and flexibility in making payments and protect against various potential restrictions and threats related to e‐payments. Consumers' holding of cash as an additional option depends on three key factors: attitude toward cash, particularly the flexibility it offers, unusual purchasing situations, and perceived card or mobile payment risk, considered as a moderator. In the debate on the future of cash, the study supports the position that cash has a place in the modern payment system, although it plays a different role. Cash is a supportive backup solution. Eliminating cash significantly reduces consumer welfare.
Efficacy of communicating periodontal risk on psychological outcomes and supragingival plaque control in patients undergoing first periodontal consultation: A parallel‐arm, randomized trial
Authors: Farina Roberto , Simonelli Anna , Guarnelli Maria Elena , Secchiati Giacomo , Montemezzo Giulia , Scapoli Chiara , Trombelli Leonardo 
Published: July 2024

AbstractAimTo evaluate the efficacy of the PerioRisk prognostic tool in implementing the effect of motivational interviewing (MI) on psychological outcomes and supragingival plaque control.Materials and MethodsParticipants underwent MI immediately after their first periodontal visit. According to a parallel‐arm, randomized study design, MI was performed with (RISK group) or without (CTR group) information on PerioRisk level and treatment goals based on PerioRisk output. Psychological outcomes were assessed using the Positive Affect Negative Affect Scale (PANAS) and Protection Motivation Theory (PMT). Plaque index (PI) was re‐evaluated after 8–12 weeks.ResultsSignificant improvements in PMT overall score and PI were observed in CTR and RISK groups, without inter‐group difference in PANAS and PMT overall scores and PI. A sub‐analysis showed that the overall PMT scores recorded immediately after MI in both CTR and RISK groups for subjects with no tooth loss due to periodontitis were higher than those recorded before MI in subjects with tooth loss due to periodontitis.ConclusionsAt first periodontal visit, MI (implemented with without PerioRisk) has tangible effects on psychological outcomes and supragingival plaque control and seems to anticipate the awareness that is commonly generated by periodontitis‐related tooth loss (ClinicalTrials.gov protocol registration ID: NCT05078411).
Explicit inference: A meta‐replication of SEER cancer registry research evaluating the Affordable Care Act's Medicaid expansion
Authors: Semprini Jason 
Published: July 2024

AbstractObjectivesAmong the provisions within the Affordable Care Act (ACA), expanding Medicaid was arguably the greatest contributor to increasing access to care. For over a decade, researchers have investigated how Medicaid expansion impacted cancer outcomes. Over this same decade, statistical theory illuminated how state‐based policy research could be compromised by invalid inference. After reviewing the literature to identify the inference strategies of state‐based cancer registry Medicaid expansion research, this study aimed to assess how inference decisions could change the interpretation of Medicaid expansion's impact on staging, treatment, and mortality in cancer patients.Data sourcesCancer case data (2000–2019) was obtained from the Surveillance, Epidemiology, End Results (SEER) programme. Cases included all cancer sites combined, top 10 cancer sites combined, and three screening amenable cancers (colorectal, female breast, female cervical).Study designA Difference‐in‐Differences design estimated the association between Medicaid expansion and four binary outcomes: distant stage, initiating treatment >1 month after diagnosis, no surgery recommendation, and death. Three inference techniques were compared: (1) traditional, (2) cluster, and (3) Wild Cluster Bootstrap.Data collectionData was accessed via SEER*Stat.Principal findingsEstimating standard errors via traditional inference would suggest that Medicaid expansion was associated with delayed treatment initiation and surgery recommendations. Traditional and clustered inference also suggested that Medicaid expansion reduced mortality. Inference using Wild Cluster Bootstrap techniques never rejected the null hypotheses.ConclusionsThis study reiterates the importance of explicit inference. Future state‐based, cancer policy research can be improved by incorporating emerging techniques. These findings warrant caution when interpreting prior SEER research reporting significant effects of Medicaid expansion on cancer outcomes, especially studies that did not explicitly define their inference strategy.
Methods and approaches for developing plain language versions of guidelines recommendations: Scoping review protocol
Authors: Friessová Tereza , Langaufová Alena , Dolanová Dana , Beharková Natália , Vrbová Tereza , Búřilová Petra , Pokorná Andrea 
Published: July 2024

AbstractAims and ObjectivesThis is a protocol of a scoping review that will aim to synthesise methodological evidence on formulating plain language versions of recommendations from guidelines both for clinical practice and for public health.MethodWe will conduct a search in MEDLINE (Ovid), Embase (Ovid) databases, and webpages of guidelines developers with no language and date limitations. The title/abstract and full‐text screening will be performed by two reviewers independently. The team of reviewers will extract data on methods used for developing plain language versions of recommendations in a standardised manner. The data analysis and synthesis will be presented narratively in tabular form.Results and ConclusionWe will conduct a scoping review based on this protocol.
Can large language models provide accurate and quality information to parents regarding chronic kidney diseases?
Authors: Naz Rüya , Akacı Okan , Erdoğan Hakan , Açıkgöz Ayfer 
Published: July 2024

AbstractRationaleArtificial Intelligence (AI) large language models (LLM) are tools capable of generating human‐like text responses to user queries across topics. The use of these language models in various medical contexts is currently being studied. However, the performance and content quality of these language models have not been evaluated in specific medical fields.Aims and objectivesThis study aimed to compare the performance of AI LLMs ChatGPT, Gemini and Copilot in providing information to parents about chronic kidney diseases (CKD) and compare the information accuracy and quality with that of a reference source.MethodsIn this study, 40 frequently asked questions about CKD were identified. The accuracy and quality of the answers were evaluated with reference to the Kidney Disease: Improving Global Outcomes guidelines. The accuracy of the responses generated by LLMs was assessed using F1, precision and recall scores. The quality of the responses was evaluated using a five‐point global quality score (GQS).ResultsChatGPT and Gemini achieved high F1 scores of 0.89 and 1, respectively, in the diagnosis and lifestyle categories, demonstrating significant success in generating accurate responses. Furthermore, ChatGPT and Gemini were successful in generating accurate responses with high precision values in the diagnosis and lifestyle categories. In terms of recall values, all LLMs exhibited strong performance in the diagnosis, treatment and lifestyle categories. Average GQ scores for the responses generated were 3.46 ± 0.55, 1.93 ± 0.63 and 2.02 ± 0.69 for Gemini, ChatGPT 3.5 and Copilot, respectively. In all categories, Gemini performed better than ChatGPT and Copilot.ConclusionAlthough LLMs provide parents with high‐accuracy information about CKD, their use is limited compared with that of a reference source. The limitations in the performance of LLMs can lead to misinformation and potential misinterpretations. Therefore, patients and parents should exercise caution when using these models.
Star wars: The hidden empire
Authors: Yadin‐Israel Azzan 
Published: July 2024

AbstractThe remarkable cultural vitality of Star Wars and the subsequent franchise is due in part to the way in which it simultaneously builds on and bolsters the Gramscian “common sense” that America is not an empire. Like the Western, Star Wars uses apolitical individualism to portray political actions as the result of individuals' search for freedom, while representing the galaxy as home to a single, evil Empire. These narrative mechanisms, invite the viewers of Star Wars to think of the United States as a ragtag group of fighters battling an oppressive empire, but not itself an empire.
Assessing bias in the causal role of HPV in oral cancer: A systematic review and meta‐analysis
Authors: Kaur Gagandeep , Yap Tami , Ramani Rishi , McCullough Michael , Singh Ankur 
Published: July 2024

AbstractObjectiveHigh‐risk human papillomaviruses (HPV) are an established cause of oropharyngeal cancer. Their relationship with oral cancer remains unclear with detection ranging from 0% to 100%. HPV DNA detection or evidence of exposure alone is insufficient to conclude causality. This systematic review assesses the extent of bias in studies of HPV detection in cancers of the oral cavity.MethodsPubMed, Ovid MEDLINE, EMBASE, and PsycInfo databases were searched for observational studies reporting the effect of HPV in oral cavity specific cancers.ResultsAll 15 included studies presented HPV DNA detection or serum HPV‐antibodies, none included mRNA E6/E7 analysis. Cases with oral cancer had 5.36 times (95% CI 3.29–8.72) higher odds of having HPV detected compared to controls. The odds of HPV detection were higher in cell‐based (OR 6.93; 95% CI 0.82–58.55) and tissue samples (OR 5.28; 95% CI 3.41–8.18) than blood‐based samples (OR 3.36; 95% CI 1.53–7.40).ConclusionWhen cancer site is clearly differentiated between oropharynx and oral cavity, 12 studies showed strong association between HPV and oral cancer, but the available estimates lack internal validity due to inconsistent measurements, high confounding, and lack of gold standard testing. There is not high‐quality evidence to conclude a causal relationship of HPV with oral cancer.
Revisiting “Bounded Spaces in the Mobile World”: A Contextualized Rejoinder
Authors: Paasi Anssi 
Published: July 2024

AbstractThis contribution aims firstly to contextualize the author's article Bounded spaces in the mobile world: Deconstructing “regional identity” and, secondly, to give a response to four invited comments on that article published on this forum. This paper is organized as follows. After the introduction, the geographical and conceptual contextualization of the TESG article and the scientific links behind the article will be discussed. These are followed by a response to four comments.
Conducting a successful diet trial for the diagnosis of food allergy in dogs and cats
Authors: Jackson Hilary A. , Dembele Veronique 
Published: July 2024

AbstractA limited antigen diet trial and subsequent food provocation is currently the optimal method of confirming a diagnosis of food allergy in dogs and cats. However, performing an effective diet trial can be challenging as it requires a high level of client and pet compliance, appropriate diet selection and correct interpretation of the provocative challenge. This narrative guides the clinician through the process, highlights potential pitfalls and specifies how these can be avoided to achieve a successful outcome.
Print-N-Grip: A Disposable, Compliant, Scalable, and One-Shot 3D-Printed Multifingered Robotic Hand
Authors: Laron Alon , Sne Eran , Perets Yaron , Sintov Avishai 
Published: July 2024

Abstract
Robotic hands are an important tool for replacing humans in handling toxic or radioactive materials. However, these are usually highly expensive, and in many cases, once they are contaminated, they cannot be re-used. Some solutions cope with this challenge by 3D printing parts of a tendon-based hand. However, fabrication requires additional assembly steps. Therefore, a novice user may have difficulties fabricating a hand upon contamination of the previous one. We propose the Print-N-Grip (PNG) hand, which is a tendon-based underactuated mechanism able to adapt to the shape of objects. The hand is fabricated through one-shot 3D printing with no additional engineering effort and can accommodate a number of fingers as desired by the practitioner. Due to its low cost, the PNG hand can be easily detached from a universal base for disposing upon contamination and replaced by a newly printed one. In addition, the PNG hand is scalable such that one can effortlessly resize the computerized model and print. We present the design of the PNG hand along with experiments to show the capabilities and high durability of the hand.
An essential host dietary fatty acid promotes TcpH inhibition of TcpP proteolysis promoting virulence gene expression in
Vibrio cholerae
Authors: Demey Lucas M. , Sinha Ritam , DiRita Victor J. 
Published: July 2024

ABSTRACT

Vibrio cholerae
is a Gram-negative gastrointestinal pathogen responsible for the diarrheal disease cholera. Expression of key virulence factors, cholera toxin and toxin-coregulated pilus, is regulated directly by ToxT and indirectly by two transmembrane transcription regulators (TTRs), ToxR and TcpP, that promote the expression of
toxT
. TcpP abundance and activity are controlled by TcpH, a single-pass transmembrane protein, which protects TcpP from a two-step proteolytic process known as regulated intramembrane proteolysis (RIP). The mechanism of TcpH-mediated protection of TcpP represents a major gap in our understanding of
V. cholerae
pathogenesis. The absence of
tcpH
leads to unimpeded degradation of TcpP
in vitro
and a colonization defect in a neonate mouse model of
V. cholerae
colonization. Here, we show that TcpH protects TcpP from RIP
via
direct interaction. We also demonstrate that α-linolenic acid, a dietary fatty acid, promotes TcpH-dependent inhibition of RIP
via
co-association of TcpP and TcpH molecules within detergent-resistant membranes (DRMs) in a mechanism requiring the TcpH transmembrane domain. Taken together, our data support a model where
V. cholerae
cells use exogenous α-linolenic acid to remodel the phospholipid bilayer
in vivo
, leading to co-association of TcpP and TcpH within DRMs where RIP of TcpP is inhibited by TcpH, thereby promoting
V. cholerae
pathogenicity.

IMPORTANCE

Vibrio cholerae
continues to pose a significant global burden on health and an alternative therapeutic approach is needed, due to evolving multidrug resistance strains. Transcription of
toxT
, stimulated by TcpP and ToxR, is essential for
V. cholerae
pathogenesis. Our results show that TcpP, one of the major regulators of
toxT
gene expression, is protected from proteolysis by TcpH,
via
direct interaction. Furthermore, we identified a gut metabolite, α-linolenic acid, that stimulates the co-association of TcpP and TcpH within detergent-resistant membranes (also known as lipid-ordered membrane domains), thereby supporting TcpH-dependent antagonism of TcpP proteolysis. Data presented here extend our knowledge of RIP, virulence gene regulation in
V. cholerae
, and, to the best of our knowledge, provides the first evidence that lipid-ordered membranes exist within
V. cholerae
. The model presented here also suggests that TTRs, common among bacteria and archaea, and co-component signal transduction systems present in
Enterobacteria
, could also be influenced similarly.
Going fishing: how to get what you want from a fungal genetic screen
Authors: O'Meara Teresa R. 
Published: July 2024

ABSTRACT

Five years ago, as I was starting my lab, I wrote about two functional genomic screens in fungi that had inspired me (mSphere 4:e00299-19,
https://doi.org/10.1128/mSphere.00299-19
). Now, I want to discuss some of the principles and questions that I ask myself and my students as we embark on our own screens. A good screen, whether it is a genetic or chemical screen, can be the starting point for new discovery and an excellent basis for the beginning of a scientific research project. However, screens are often criticized for being “fishing expeditions.” To stretch this metaphor to the extreme, this is because people are worried that we do not know how to fish, that we will come home without any fish, bring home the wrong fish, or not know what to do with a fish if we caught it. How you set up the screen and analyze the results determines whether the screen will be useful. In this mini-review, and in the spirit of teaching a scientist to fish, I will discuss recent excellent fungal genetic and chemical screens that illustrate some of the key aspects of a successful screen.