bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ameliorative role of gemfibrozil against partial abdominal aortic constriction-induced cardiac hypertrophy in rats
Authors: Singh Amrit Pal , Singh Randhir , Krishan Pawan 
Published: June 2014

AbstractFibrates are peroxisome proliferator-activated receptor-α agonists and are clinically used for treatment of dyslipidemia and hypertriglyceridemia. Fenofibrate is reported as a cardioprotective agent in various models of cardiac dysfunction; however, limited literature is available regarding the role of gemfibrozil as a possible cardioprotective agent, especially in a non-obese model of cardiac remodelling. The present study investigated the role of gemfibrozil against partial abdominal aortic constriction-induced cardiac hypertrophy in rats. Cardiac hypertrophy was induced by partial abdominal aortic constriction in rats and they survived for 4 weeks. The cardiac hypertrophy was assessed by measuring left ventricular weight to body weight ratio, left ventricular wall thickness, and protein and collagen content. The oxidative stress in the cardiac tissues was assessed by measuring thiobarbituric acid-reactive substances, superoxide anion generation, and reduced glutathione level. The haematoxylin–eosin and picrosirius red staining was used to observe cardiomyocyte diameter and collagen deposition, respectively. Moreover, serum levels of cholesterol, high-density lipoproteins, triglycerides, and glucose were also measured. Gemfibrozil (30 mg/kg,p.o.) was administered since the first day of partial abdominal aortic constriction and continued for 4 weeks. The partial abdominal aortic constriction-induced cardiac oxidative stress and hypertrophy are indicated by significant change in various parameters used in the present study that were ameliorated with gemfibrozil treatment in rats. No significant change in serum parameters was observed between various groups used in the present study. It is concluded that gemfibrozil ameliorates partial abdominal aortic constriction-induced cardiac oxidative stress and hypertrophy and in rats.
Successful implantation of a dual-chamber pacemaker in an ELBW infant for long QT syndrome
Authors: McCrossan Brian , d’Udekem Yves , Davis Andrew Mark , Pflaumer Andreas 
Published: June 2014

AbstractLong QT syndromes encompass the most prevalent group of ion channelopathies. Long QT syndromes are predominantly familial and predispose the affected individual to ventricular arrhythmias and sudden death. Permanent pacemaker insertion for long QT syndrome is discouraged apart from younger patients exhibiting 2:1 atrioventricular block. However, permanent pacemaker insertion is a relatively common procedure in neonates with atrioventricular block, and dual-chamber permanent pacemaker insertion in low birth weight infants is challenging. We describe the management of long QT syndrome − type 2 − presenting in an extremely preterm neonate including epicardial, dual-chamber permanent pacemaker insertion.
Transposition of the great arteries and sinus venosus defect with partially anomalous pulmonary venous return: physiological and anatomic considerations
Authors: Raju Vijayakumar , Rathod Rahul , Quinonez Luis G. , Baird Christopher W. 
Published: June 2014

AbstractTransposition of the great arteries is a common congenital heart defect causing cyanosis in neonates, occurring in 0.2 per 1000 live births. It has been reported to occur with other associated congenital heart lesions. However, its association with a superior sinus venosus defect and partially anomalous pulmonary venous return has not been reported. We present a neonate with transposition of the great arteries, superior sinus venosus defect with partially anomalous pulmonary venous return that underwent successful complete neonatal repair, and discuss important physiological and anatomic considerations.
Existential behavioral therapy for informal caregivers of palliative patients: Barriers and promoters of support utilization
Authors: Thurn Tamara , Brandstätter Monika , Fensterer Veronika , Küchenhoff Helmut , Fegg Martin Johannes 
Published: June 2014

AbstractObjective:Several interventions have been developed during recent years to support informal caregivers of palliative patients. However, these trials reported low enrollment rates. Employing a newly developed group intervention, existential behavioral therapy (EBT), one study reported that only 13.6% of approached informal caregivers participated. The purpose of our present study was to identify the reasons for this low enrollment rate in order to improve future support designs.Method:All participants in the EBT trial (intervention vs. standard-care control group) as well as those who declined participation during a 4-month recruitment period were studied prospectively over 12 months. Andersen's behavioral model of healthcare service use was employed to identify group differences between acceptors and decliners: predisposing (age, gender, education, family status, relationship), enabling (social support, distance to hospital, caring vs. bereaved), and need factors (psychological distress, quality of life) were evaluated in a binary-logistic model.Results:Some 94 decliners were compared to 160 EBT participants (n = 81 intervention, n = 79 control). Caregivers who took part were significantly more distressed and suffered from a lower quality of life compared to decliners. Not only these need factors but also predisposing (age <55 years) and enabling (use of social/professional support, familiarity with caregiving institution) factors were associated with EBT utilization. At the 12-month follow-up, EBT intervention participants reported greater quality of life improvements than decliners or controls (p = 0.05). While all groups had mean anxiety scores below the cutoff at 12-month follow-up, decliners showed better improvement in anxiety compared to EBT participants (intervention p = 0.04, controls p = 0.03).Significance of results:On average, decliners are less burdened: they may be more resilient, may have better coping strategies, or already have a sufficient support network in place. Screening caregivers with regard to their experienced quality of life and targeting those in need, especially younger caregivers with low levels of quality of life, may help to allocate resources more appropriately.
Can marine bacteria be recruited from freshwater sources and the air?
Authors: Comte Jérôme , Lindström Eva S , Eiler Alexander , Langenheder Silke 
Published: June 2014

Abstract
There is now clear evidence that microorganisms present biogeographic patterns, yet the processes that create and maintain them are still not well understood. In particular, the contribution of dispersal and its exact impact on local community composition is still unclear. For example, dispersing cells may not thrive in recipient environments, but may still remain part of the local species pool. Here, we experimentally tested if marine bacteria can be retrieved from freshwater communities (pelagic and sediment) and the atmosphere by exposing bacteria from three lakes, that differ in their proximity to the Norwegian Sea, to marine conditions. We found that the percentage of freshwater taxa decreased with increasing salinities, whereas marine taxa increased along the same gradient. Our results further showed that this increase was stronger for lake and sediment compared with air communities. Further, significant increases in the average niche breadth of taxa were found for all sources, and in particular lake water and sediment communities, at higher salinities. Our results therefore suggests that marine taxa can readily grow from freshwater sources, but that the response was likely driven by the growth of habitat generalists that are typically found in marine systems. Finally, there was a greater proportion of marine taxa found in communities originating from the lake closest to the Norwegian Sea. In summary, this study shows that the interplay between bacterial dispersal limitation and dispersal from internal and external sources may have an important role for community recovery in response to environmental change.
Al13@Pt42 Core-Shell Cluster for Oxygen Reduction Reaction
Authors: Xiao B. B. , Zhu Y. F. , Lang X. Y. , Wen Z. , Jiang Q. 
Published: June 2014

AbstractTo increase Pt utilization for oxygen reduction reaction (ORR) in fuel cells, reducing particle sizes of Pt is a valid way. However, poisoning or surface oxidation limits the smallest size of Pt particles at 2.6 nm with a low utility of 20%. Here, using density functional theory calculations, we develop a core-shell Al13@Pt42cluster as a catalyst for ORR. Benefit from alloying with Al in this cluster, the covalent Pt-Al bonding effectively activates the Pt atoms at the edge sites, enabling its high utility up to 70%. Valuably, the adsorption energy of O is located at the optimal range with 0.0–0.4 eV weaker than Pt(111), while OH-poisoning does not observed. Moreover, ORR comes from O2dissociation mechanism where the rate-limiting step is located at OH formation from O and H with a barrier of 0.59 eV, comparable with 0.50 eV of OH formation from O and H2O on Pt(111).
Factors Affecting Partial Migration in Puget Sound Coho Salmon
Authors: Rohde Jessica , Fresh Kurt L. , Quinn Thomas P. 
Published: June 2014

Abstract
Partial migration, the behavior pattern in which a portion of a population migrates while others do not, is a widespread phenomenon with ecological and evolutionary consequences. Most Coho Salmon Oncorhynchus kisutch from Puget Sound, Washington, migrate to feed over the continental shelf or offshore in the North Pacific Ocean, but some remain in the semiestuarine waters of Puget Sound and are termed residents. The objective of this study was to determine which of several factors influenced residency in Puget Sound Coho Salmon. Coded wire tag recovery data showed that resident Coho Salmon were smaller than their migratory counterparts, and we used this size difference and the relative catch patterns along the coast and in Puget Sound to classify Coho Salmon caught in Puget Sound between November and August as residents. We then analyzed the effects of location of origin, day of release, weight at release, hatchery or wild rearing, and year on the proportion of fish caught as residents. Based on 268 release groups between 1975 and 1992, we classified 3.4% of fish recovered as residents, 61.3% as migrants, and 35.3% as ambiguous because they were recovered in Puget Sound in September and October, when residents and migrants were mixed. The proportion of residents varied as a function of year, basin, and day of the year. Releases into south Puget Sound produced the highest proportion of residents, and resident fish tended to be recovered in the basin where they entered Puget Sound. While other factors may influence residency in Coho Salmon, the effects of day of release and location of origin may be useful for management of these populations, as the tendency to remain in Puget Sound or migrate to the coast affects the fisheries in which the fish are taken and their growth rate, their uptake of contaminants, and their role in food webs.
Received August 15, 2013; accepted February 3, 2014
Performance of a Surface Bypass Structure to Enhance Juvenile Steelhead Passage and Survival at Lower Granite Dam, Washington
Authors: Adams Noah S. , Plumb John M. , Perry Russell W. , Rondorf Dennis W. 
Published: June 2014

Abstract
An integral part of efforts to recover stocks of Pacific salmon Oncorhynchus spp. and steelhead O. mykiss in Pacific Northwest rivers is to increase passage efficacy and survival of juveniles past hydroelectric dams. As part of this effort, we evaluated the efficacy of a prototype surface bypass structure, the removable spillway weir (RSW), installed in a spillbay at Lower Granite Dam, Washington, on the Snake River during 2002, 2003, 2005, and 2006. Radio-tagged juvenile steelhead were released upstream from the dam and their route of passage through the turbines, juvenile bypass, spillway, or RSW was recorded. The RSW was operated in an on-or-off condition and passed 3–13% of the total discharge at the dam when it was on. Poisson rate models were fit to the passage counts of hatchery- and natural-origin juvenile steelhead to predict the probability of fish passing the dam. Main-effect predictor variables were RSW operation, diel period, day of the year, proportion of flow passed by the spillway, and total discharge at the dam. The combined fish passage through the RSW and spillway was 55–85% during the day and 37–61% during the night. The proportion of steelhead passing through nonturbine routes was &lt;88% when the RSW was off during the day and increased to &gt;95% when the RSW was on during the day. The ratio of the proportion of steelhead passed to the proportion of water passing the RSW was from 6.3:1 to 10.0:1 during the day and from 2.7:1 to 5.2:1 during the night. Steelhead passing through the RSW exited the tailrace about 15 min faster than fish passing through the spillway. Mark–recapture single-release survival estimates for steelhead passing the RSW ranged from 0.95 to 1.00. The RSW appeared to be an effective bypass structure compared with other routes of fish passage at the dam.
Received June 13, 2013; accepted February 2, 2014
Genetic Identification of Chinook Salmon in the Columbia River Estuary: Stock-Specific Distributions of Juveniles in Shallow Tidal Freshwater Habitats
Authors: Teel David J. , Bottom Daniel L. , Hinton Susan A. , Kuligowski David R. , McCabe George T. , McNatt Regan , Roegner G. Curtis , Stamatiou Lia A. , Simenstad Charles A. 
Published: June 2014

Abstract
Extensive efforts are underway to restore and conserve nearshore shallow water habitats in the Columbia River estuary with the intent of increasing the estuary's capacity to provide food, refuge, and other crucial ecosystem functions for juvenile salmon. Juvenile Chinook Salmon Oncorhynchus tshawytscha, including those from the five Evolutionarily Significant Units listed as threatened or endangered under the U.S. Endangered Species Act, are particularly expected to benefit from the habitat improvements. However, information on the temporal and spatial estuarine distributions of juveniles from specific populations or stocks is lacking and impedes restoration planning for at-risk salmon. We conducted a series of surveys to sample juvenile Chinook Salmon occupying shallow-water habitats with sandy beaches in six hydrogeomorphic reaches across the tidal freshwater portion of the estuary and also at one long-term reference site near the estuary mouth. Sites were sampled bimonthly over 26 months during 2010–2012 to capture seasonal patterns of stock-specific habitat use. Genetic stock identification analyses were conducted on the samples using microsatellite DNA loci and genotypic data representing spawning populations from throughout the Columbia River basin. We identified three tidal freshwater areas that could be distinguished by genetic stock composition. Lower tidal freshwater reaches were dominated by fall-run juveniles from West Cascade tributaries (&gt;70%), upper reaches had a large proportion of fish from the upper Columbia River summer–fall stock (&gt;60%), and middle reaches were characterized by greater stock diversity with no single stock contributing more than 30% in each reach. Stock-specific juvenile habitat use differed by season, life history type, and between natural and hatchery-produced fish. Data from this study provide improved descriptions of the near-shore estuary habitat use of several Columbia River genetic stocks of Chinook Salmon that can assist managers in the design and selection of estuary restoration projects.
Received November 11, 2013; accepted February 18, 2014
Quantifying the Effectiveness of Conservation Measures to Control the Spread of Anthropogenic Hybridization in Stream Salmonids: a Climate Adaptation Case Study
Authors: Al-Chokhachy Robert , Muhlfeld Clint C. , Boyer Matthew C. , Jones Leslie A. , Steed Amber , Kershner Jeffrey L. 
Published: June 2014

Abstract
Quantifying the effectiveness of management actions to mitigate the effects of changing climatic conditions (i.e., climate adaptation) can be difficult, yet critical for conservation. We used population genetic data from 1984 to 2011 to assess the degree to which ambient climatic conditions and targeted suppression of sources of nonnative Rainbow Trout Oncorhynchus mykiss have influenced the spread of introgressive hybridization in native populations of Westslope Cutthroat Trout O. clarkii lewisi. We found rapid expansion in the spatial distribution and proportion of nonnative genetic admixture in hybridized populations from 1984 to 2004, but minimal change since 2004. The spread of hybridization was negatively correlated with the number of streamflow events in May that exceeded the 75th percentile of historic flows (r = −0.98) and positively correlated with August stream temperatures (r = 0.89). Concomitantly, suppression data showed a 60% decline in catch per unit effort for fish with a high proportion of Rainbow Trout admixture, rendering some uncertainty as to the relative strength of factors controlling the spread of hybridization. Our results illustrate the importance of initiating management actions to mitigate the potential effects of climate change, even where data describing the effectiveness of such actions are initially limited but the risks are severe.
Received November 22, 2013; accepted March 1, 2014
Size Selective Feeding in Captive and Free Ranging Atlantic Bluefin Tuna
Authors: Butler Christopher M. , Hanrahan Brian , Buckel Jeffrey A. , Rudershausen Paul J. , Juanes Francis , Smith Joseph W. 
Published: June 2014

Abstract
We examined size selective feeding in captive and free ranging Atlantic Bluefin Tuna Thunnus thynnus. For the captive study, Bluefin Tuna were maintained in a cylindrical net pen enclosure (30.5 m in diameter; 15.2 m deep) located 32.2 km offshore of Virginia. Tests of prey size selectivity by captive Bluefin Tuna were observed using underwater video. In free ranging Bluefin Tuna, size selection was examined by comparing the sizes of Atlantic Menhaden Brevoortia tyrannus found in stomach contents with the sizes of those collected during the fall purse seine fishery for Atlantic Menhaden off the North Carolina coast. Captive Bluefin Tuna selected larger prey when prey length : predator length ratios (PPRs) were less than 10%; however, size selectivity was not observed when the PPRs exceeded 10%. For free ranging Bluefin Tuna, PPRs were mostly greater than 10% (12.98 ± 0.06% [mean ± SE]), and there were no significant differences in length between Atlantic Menhaden from stomach contents and those from purse seine collections. The minimum and median sizes of Atlantic Menhaden prey increased with increasing predator size; however, the maximum size of Atlantic Menhaden prey did not change, indicating that the smallest Bluefin Tuna sampled could consume the largest Atlantic Menhaden. We conclude that the relatively small size of forage fishes commonly observed in Bluefin Tuna stomachs was likely due to the high abundance of these fishes in the environment rather than to active selection for small prey.
Received August 29, 2013; accepted January 14, 2014
Small Scale Vertical Movements of Summer Flounder Relative to Diurnal, Tidal, and Temperature Changes
Authors: Henderson Mark J. , Fabrizio Mary C. 
Published: June 2014

Abstract
Observation of animal movements on small spatial scales provides a means to understand how large scale species distributions are established from individual behavioral decisions. Small scale vertical movements of 14 Summer Flounder Paralichthys dentatus residing in Chesapeake Bay were observed by using depth data collected with archival tags. A generalized linear mixed model was employed to examine the relationship between these vertical movements and environmental covariates such as tidal state, time of day, lunar phase, and temperature. Vertical movements increased with warming water temperatures, and this pattern was most apparent at night and during rising and falling tides. Fish generally exhibited greater vertical movements at night, but the difference between vertical movements in the day and those at night decreased as fish increased in size. Results from this study fill a void in understanding the small scale movements of Summer Flounder and could be incorporated into individual based models to investigate how species distributions develop in response to environmental conditions.
Received October 28, 2013; accepted January 28, 2014
EuGene-PP: a next-generation automated annotation pipeline for prokaryotic genomes
Authors: Sallet Erika , Gouzy Jérôme , Schiex Thomas 
Published: June 2014

Abstract
Summary: It is now easy and increasingly usual to produce oriented RNA-Seq data as a prokaryotic genome is being sequenced. However, this information is usually just used for expression quantification. EuGene-PP is a fully automated pipeline for structural annotation of prokaryotic genomes integrating protein similarities, statistical information and any oriented expression information (RNA-Seq or tiling arrays) through a variety of file formats to produce a qualitatively enriched annotation including coding regions but also (possibly antisense) non-coding genes and transcription start sites.
Availability and implementation: EuGene-PP is an open-source software based on EuGene-P integrating a Galaxy configuration. EuGene-PP can be downloaded at eugene.toulouse.inra.fr.
Contact: erika.sallet@toulouse.inra.fr
Supplementary information: Supplementary data are available at Bioinformatics online.
Sushi.R: flexible, quantitative and integrative genomic visualizations for publication-quality multi-panel figures
Authors: Phanstiel Douglas H. , Boyle Alan P. , Araya Carlos L. , Snyder Michael P. 
Published: June 2014

AbstractMotivation: Interpretation and communication of genomic data require flexible and quantitative tools to analyze and visualize diverse data types, and yet, a comprehensive tool to display all common genomic data types in publication quality figures does not exist to date. To address this shortcoming, we present Sushi.R, an R/Bioconductor package that allows flexible integration of genomic visualizations into highly customizable, publication-ready, multi-panel figures from common genomic data formats including Browser Extensible Data (BED), bedGraph and Browser Extensible Data Paired-End (BEDPE). Sushi.R is open source and made publicly available through GitHub ( https://github.com/dphansti/Sushi ) and Bioconductor ( http://bioconductor.org/packages/release/bioc/html/Sushi.html ).Contact: mpsnyder@stanford.edu or dphansti@stanford.edu