bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of prenatal exercise interventions on maternal body composition: A secondary analysis of the FitMum randomized controlled trial
Authors: Roland Caroline Borup , Seyedhosseini Parisa , Knudsen Signe de Place , Jessen Anne Dsane , Jensen Ida Karoline Bach , Bendix Jane M. , van Hall Gerrit , Molsted Stig , Alomairah Saud Abdulaziz , Løkkegaard Ellen , Stallknecht Bente , Clausen Tine D. 
Published: August 2024

The main objective of the study was to investigate the effects of prenatal exercise interventions on maternal body composition at 28 weeks gestation and 7–14 days after delivery. We also explored associations between physical activity (PA) per se and body composition. This study presents secondary outcomes of the FitMum randomized controlled trial, which included healthy inactive pregnant women at gestational age ≤ 15+0 weeks. They were randomized to structured supervised exercise training, motivational counselling on PA, or standard care. Maternal body composition was measured by doubly labeled water at 28 weeks gestation (n = 134) and by dual-energy X-ray absorptiometry scan 7–14 days after delivery (n = 117). PA, including moderate-to-vigorous-intensity PA (MVPA), active kilocalories, and steps, were measured continuously from inclusion to delivery by a wrist-worn activity tracker. One hundred fifty pregnant women were included with a median pre-pregnancy body mass index (BMI) of 24.1 (21.6–27.9) kg/m2. We found no differences between groups in fat mass, fat percentage or fat-free mass at 28 weeks gestation or 7–14 days after delivery. Visceral adipose tissue mass and bone mineral density measured 7–14 days after delivery did not differ between groups either. Linear regression analyses adjusted for pre-pregnancy BMI showed that a higher number of daily steps was associated with lower fat mass, fat percentage, and visceral adipose tissue mass at 28 weeks gestation and 7–14 days after delivery. Active kilocalories during pregnancy was positively associated with fat-free mass 7–14 days after delivery. Neither structured supervised exercise training nor motivational counselling on PA during pregnancy affected maternal body composition at 28 weeks gestation or 7–14 days after delivery compared to standard care. Interestingly, when adjusted for pre-pregnancy BMI, higher number of daily steps was associated with lower fat content during pregnancy and after delivery, whereas MVPA and active kilocalories were not.
Trial registration: ClinicalTrials.gov; NCT03679130; 20/09/2018.
Lactate dehydrogenase can be used for differential diagnosis to identify patients with severe polytrauma with or without chest injury—A retrospective study
Authors: Yan Weining , Bläsius Felix , Wahl Tabea , Hildebrand Frank , Balmayor Elizabeth Rosado , Greven Johannes , Horst Klemens 
Published: August 2024

Background
Chest injury is an important factor regarding the prognosis of patients with polytrauma (PT), and the rapid diagnosis of chest injury is of utmost importance. Therefore, the current study focused on patients’ physiology and laboratory findings to quickly identify PT patients with chest injury.

Method
Data on 64 PT patients treated at a trauma center level I between June 2020 and August 2021 were retrospectively collected. The patients were divided into a PT group without chest injury (Group A) and a PT group including chest injury (Group B). The relationship between chest injury and the patients’ baseline characteristics and biochemical markers was analyzed.

Results
Heart rate, respiration rate, Sequential Organ Failure Assessment (SOFA) score, glutamate oxaloacetate aminotransferase (GOT), glutamate pyruvate transaminase (GPT), creatine kinase MB (CK-MB), leucocytes, hemoglobin (Hb), platelets, urine output, lactate, and lactate dehydrogenase (LDH) in groups A and B exhibited statistically significant differences at certain time points. Multifactorial analysis showed that blood LDH levels at admission were associated with chest injury (P = 0.039, CI 95% 1.001, 1.022).

Conclusion
LDH may be a promising indicator for screening for the presence of chest injury in patients with severe polytrauma.
Polatuzumab vedotin combined with bendamustine and rituximab for relapsed/refractory diffuse large B-cell lymphoma: A systematic review protocol
Authors: Eslami Mohammadreza , Mehrabi Mahdi , Payandeh Mehrdad , Saba Fakhredin 
Published: August 2024

Background
Diffuse large B-cell lymphoma (DLBCL) is an aggressive non-Hodgkin lymphoma subtype with a significant relapse rate and poor prognosis in relapsed/refractory (R/R) patients. Polatuzumab vedotin in combination with bendamustine and rituximab (Pola-BR) has demonstrated promising efficacy and safety as salvage therapy for R/R DLBCL. This systematic review protocol aims to comprehensively evaluate the efficacy of Pola-BR for the treatment of R/R DLBCL by synthesizing data from relevant randomized controlled trials.

Methods
This protocol details the eligibility criteria, search strategy, study selection, data extraction, and analysis methods for the systematic review. Randomized controlled trials comparing Pola-BR with other interventions for R/R DLBCL will be included. The primary endpoint is overall survival, with secondary endpoints being progression-free survival and incidence of adverse events. A comprehensive search will be conducted across databases such as Medline/PubMed, Cochrane Library, Web of Science, Scopus, EMBASE, ProQuest, EU Clinical Trials Register, WHO International Clinical Trials Registry Platform (ICTRP), and ClinicalTrials.gov from the January 2000 to April 2024. To assess the potential risk of bias, the Cochrane Risk of Bias 1 tool will be used. Data synthesis will utilize fixed-effect or random-effects models, and subgroup and meta-regression analyses will examine heterogeneity. Additionally, publication bias and sensitivity analyses will be performed, and the GRADE approach will be applied to assess the certainty of the evidence.

Conclusion
This systematic review and meta-analysis protocol provides a rigorous framework for evaluating the efficacy of Pola-BR in the treatment of R/R DLBCL. The results will inform clinical decision-making and guideline development, addressing the unmet need for effective and tolerable treatments for this challenging patient population. Potential limitations and biases will be acknowledged, and future research directions will be discussed.
Indictment of the U.S. Federal Government, Senan Shaibani (2024)
Authors: MacDonald Leslie T. 
Published: August 2024

Review of: Indictment of the U.S. Federal Government, Senan Shaibani (2024)
Bloomington, IN: AuthorHouse, 276 pp.,
ISBN-13 979-8-82301-672-8, h/bk, USD 19.94
ISBN-13 979-8-82301-671-1, e-book, USD 6.99
Rodríguez-Avial Llardent, L. Irastorza Ruigómez, L y Escauriaza Lázaro, J. L. de (2023). En defensa de la prolongación de la Castellana. El proyecto que pudo cambiar el Norte de Madrid
Authors: Longato Davide 
Published: August 2024

Rodríguez-Avial Llardent, L. Irastorza Ruigómez, L y Escauriaza Lázaro, J. L. de (2023). En defensa de la prolongación de la Castellana. El proyecto que pudo cambiar el Norte de Madrid. Colegio de Ingenieros de Caminos, Canales y Puertos y Colegio Oficial de Arquitectos de Madrid Madrid, 455 pp. ISBN 978-84-88496-03-4
Exosomal miR‐106a‐5p derived from intermittently hypoxic non‐small‐cell lung cancer increases tumor malignancy
Authors: Ren Jie , Jin Zhuan , Huang Yongjie 
Published: August 2024

AbstractIntermittent hypoxia (IH) is a hallmark of obstructive sleep apnea (OSA), which is related to tumorigenesis and progression. We explored the possible mechanisms by which OSA may promote the development of non‐small cell lung cancer (NSCLC). In this study, NSCLC cells with and without miR‐106a‐5p inhibition were exposed to IH or room air (RA), and subsequently, exosomes were extracted and identified. Macrophages were incubated with these exosomes to detect the expression of the STAT3 signaling pathway and M2‐type macrophage markers, as well as the effect of the macrophages on the malignancy of NSCLC cells. A nude mouse tumorigenesis model was constructed to detect the effects of exosomal miR‐106a‐5p on M2 macrophage polarization and NSCLC cell malignancy. Our results showed that IH exosomes promoted the polarization of M2 macrophages, thereby promoting the proliferation, invasion, and metastasis of NSCLC cells. Further, Based on microarray analysis of RA and IH exosomes, we discovered that miR‐106a‐5p, transferred to the macrophages through exosomes, participated in this mechanism by promoting M2 macrophage polarization via down‐regulating PTEN and activating the STAT3 signaling pathway in vitro and in vivo. For patients with NSCLC and OSA, exosomal miR‐106a‐5p levels showed a positive relation to AHI. Exosomal miR‐106a‐5p represents a potential therapeutic target among patients with concomitant cancer and NSCLC.
Wissenschaft und prähistorische Forschung in fünf politischen Systemen. Robert Rudolf Schmidt (1882–1950) und die SS-Grabung Mauern 1937 bei Rennertshofen
Authors: Schöbel Gunter 
Published: August 2024

Zusammenfassung
Der Gründer des ersten freien und nichtstaatlich finanzierten Forschungsinstitutes für Ur- und Frühgeschichte in Deutschland im Jahre 1921, des UFI in Tübingen, Robert Rudolf Schmidt, verdient es, für eine bislang wenig beachtete Schlüsselphase seines Lebens nach seiner Entlassung aus dem Universitätsdienst im Frühjahr 1934 noch einmal betrachtet zu werden. Und dies, obwohl seine Person schon mehrfach aus wissenschaftlicher Sicht bewertet wurde
Bolus/Conard 2012; Fehr 2008, 99f.; Heiligmann 1992, 30–32; Häck 2020; Hülle 1951; Kater 1974, 80f.; Keefer 1992; Kimmig 1958; 1992, 16f.; v. Koenigswald/Müller-Beck/Pressmar 1974; Müller-Beck 2000; 2011, 123f.; Leube/Hegewisch 2002; Leube 2013; Strobel 2000, 20–42; 2010; Veit 2006; Schöbel 2001; 2002; 2011; 2012, 9f.; 2022; Vojkffy in: Zotz 1955, 9–12; propyläum vitae https://sempub.ub.uni-heidelberg.de/propylaeum_vitae/de/wisski/navigate/7913/view).
. Neue Dokumente aus Privatarchiven ergänzen seine Forscher-Vita und sind geeignet, unter anderem Blickwinkel fachlich bereits vorgebrachte Narrative zu seiner Person erneut zu beleuchten. Dies trifft besonders auf die unter ihm vorgenommene Ausgrabung in den paläolithischen Höhlen von Mauern bei Rennertshofen in Bayern zu, die sich bislang einer genaueren Nachschau entzogen hatte. Er war bei seinem wissenschaftlichen Wirken im 20. Jahrhundert in fünf politischen Systemen tätig. Im Kaiserreich (bis 1918), in der Weimarer Republik (bis 1933), im Nationalsozialismus (bis 1945), in der Alliiertenzeit (bis 1949) und in seinen letzten Lebensmonaten in der Bundesrepublik Deutschland (ab 1949), deren Anforderungen er sich stellte, deren Spielräume er für seine prähistorische Forschung zu nutzten versuchte, an denen er aber mehrfach scheiterte.
Making Verse in a Precarious Language: Poetry in Late 19th-Century Ukrainian Culture between Silence and Music, Present and Future
Authors: Achilli Alessandro 
Published: August 2024

Summary
In this article, I analyze instances of Ukrainian poetry written between Taras Ševčenko’s death and the establishment of modernism that deal with the theme of the precarity of Ukrainian literature as a consequence of the lack of a Ukrainian nation in those times. On the basis of examples drawn from the works of Pantelejmon Kuliš, Lesja Ukrajinka, Mychajlo Staryc’kyj, Borys Hrinčenko, Volodymyr Samijlenko, Volodymyr Šaškevyč, and Ivan Franko, I aim to show how Ukrainian poets of the second half of the 19th century tended to imagine the Ukrainian community as belonging to the past and/or the future, while its presence and its agency in the present are made impossible by imperial subjugation, hence making communication, including literary, impossible or powerless. In the final part of my article, I also reflect on the complex nexus between aesthetic judgment and the re-evaluation of Ukrainian literary history.
Effect of aerobic intermittent exercise on the decreased cognitive ability induced by PM2.5 exposure in rats
Authors: Wang Zhongwei , Qin Fei , Wu Dongzhe , Xu Minxiao , Cui Shuqiang , Zhao Jiexiu 
Published: August 2024

Abstract

Objectives
This study aimed to investigate the protective effects and underlying mechanisms of aerobic intermittent exercise on cognitive impairment by PM2.5 exposure.

Methods
Thirty-two rats were randomly divided into four groups: sedentary, exercise, sedentary + PM2.5 exposure, and exercise + PM2.5 exposure. The exercise groups underwent 8 weeks of exercise training (5 days of exercise per week). Subsequently, PM2.5 exposure groups were subjected to PM2.5 for three weeks. Post-exposure, we assessed cognitive abilities (shuttle box test), hippocampal tissue structure, related inflammatory factors (TNF-α, IL-6, IL-1β), the protein of inflammatory responses mechanism (P65, IκκB) and cognitive-related protein levels (BDNF, Aβ-42).

Results
PM2.5 exposure caused cognitive impairment, abnormal histopathological changes, reduced cognitive related protein and increased pro-inflammatory cytokine levels. Analysis of shuttle box test data revealed significant main effects on the passive avoidance latency times measured in rats (p<0.05). Aerobic intermittent exercise improves spatial learning decline in rats induced by PM2.5. Conversely, the Exercise + PM2.5 group demonstrated a significant reduction in latency of 24.9 % compared to the Sedentary + PM2.5 group (p<0.05, ES=1.41).

Conclustion
Aerobic intermittent exercise may help in protecting against the decrease of cognitive ability induced by PM2.5 exposure.
Social Commerce Success Impact on Business Performance Insight From TikTok Shop Phenomena in Indonesia
Authors: Ardiansah Muhammad Noor , Azizah Asmaul , Sadida Afiat 
Published: August 2024

Purpose : Social commerce has revolutionized as a more interactive business platform beyond e-commerce, but there are still limited studies on its success and impact on TikTok Shop’s performance case as the most popular social commerce. This study investigates the determinants of success in the framework of Delone and Mclean’s information system success model, which was developed by attributing its impact on TikTok Shop’s business performance.Method : The research was conducted on Generation Z users and entrepreneurs who use TikTok Shop as an essential part of business in Indonesia, using SEM analysis through the stages of outer model, inner model, goodness fit, and hypothesis testing.Findings : The results show that the usage level is indicated by system quality and trust, while user satisfaction is indicated by information quality, service quality, and trust, which affect the success of TikTok Shop and positively influence the seller’s business performance. Social media transformation into social commerce requires consideration of usage and user satisfaction as determinants of system success that practically affect the seller’s business performance. Novelty : The study proposes the trust variable as an extension of Delone and Mclean’s ISSM and examines its direct relationship with multidimensional seller performance so that it can be developed to enrich the existing model.
Adopción de billeteras digitales como determinante de la inclusión financiera en comerciantes ambulantes en Cusco
Authors: Cruz Hermoza Alfredo 
Published: August 2024

Objetivo: Medir a influência da adoção de carteiras digitais na inclusão financeira dos comerciantes ambulantes em Cusco. Métodos: Foi desenvolvido com base em método de abordagem quantitativa, escopo explicativo de natureza prospetiva e analítica, delineamento não experimental e corte transversal. As informações foram coletadas por meio da pesquisa como técnica e do questionário como instrumento, os quais foram aplicados a 242 participantes. A análise dos dados foi realizada por meio de modelo de regressão linear. Resultados: Foi determinado que a adoção de carteiras digitais tem uma influência significativa e positiva na inclusão financeira (β = 1.938, p < 0.05), além disso, o grau de determinação foi ótimo (R2 = 99 %). Quanto às dimensões da inclusão financeira, constatou-se que foram influenciadas pela adoção de carteiras digitais de forma significativa e positiva (p < 0.05). Conclusão: A adoção de carteiras digitais tem uma influência significativa e positiva na inclusão financeira, portanto, o acesso ao sistema financeiro para setores marginalizados requer a participação conjunta entre entidades financeiras e o Governo para propor políticas e direcionar a inclusão financeira.
Navegación de un robot Ackermann para tareas de transporte en invernaderos mediterráneos con MultiVehicle Simulator (MVSim)
Authors: Cañadas Aranega Fernando , Blanco Claraco Jose Luis , Mañas Alvarez Francisco José , Moreno Úbeda José Carlos 
Published: August 2024

La agricultura intensiva bajo invernadero se ha convertido en uno de los pilares del crecimiento demográfico de las sociedad. Sin embargo, a medida que pasan los años, el aumento de la superpoblación tanto en los humanos como en el mundo animal, supone un problema para la humanidad, por lo que la agricultura existente debe ser más eficiente y sostenible. En esta búsqueda, la automatización y, en particular, los robots, juegan un papel fundamental ya que son herramientas para la resolución óptima de algunos problemas claves en este campo relacionados con el desarrollo de tareas tediosas, sucias y/o peligrosas, las típicas tareas DDD (del inglés Dull, Dirty, Dangerous). Este trabajo se centra en uno de los resultados del proyecto Agricultural Collaborative Robots inside IoT II (AGRICOBIOT II), en particular, en un robot móvil Ackermann destinado a realizar tareas de transporte dentro de invernaderos de tipo Mediterráneo, diseñado y construido en la propia Universidad de Almería para poder trabajar de forma colaborativa con el agricultor. Este trabajo describe los detalles de este robot, validando su funcionamiento en el simulador MVSim, a partir de un modelo 3D del mismo. En particular, el trabajo se centra en el problema de navegación durante el transporte teniendo en cuenta la presencia de personas y objetos inesperados o dinámicos mediante el framework de navegación autónoma Nav2.
Interfaz inteligente de ayuda a la navegación autónoma en exteriores
Authors: Hidalgo García Luz María , Roldán Gómez Juan Jesús 
Published: August 2024

La navegación autónoma terrestre en exteriores es una tarea compleja que se enfrenta a numerosos desafíos. Las aplicaciones que consigan fusionar diferentes tipos de información para la ayuda a la toma de decisiones serán las más exitosas. Se presenta el desarrollo de una interfaz inteligente para ofrecer asistencia a la navegación autónoma proporcionando información de las posibles rutas a seguir en el mapa geográfico por el que se lleva a cabo la navegación. Integra buscadores de rutas de menor coste de proveedores de mapas evitando zonas virtuales restringidas incorporadas al escenario. Para zonas de exploración no muy grandes en las que no existan rutas registradas en los mapas, el sistema incorpora un algoritmo ad-hoc para encontrar la ruta óptima. Este proyecto integra tres importantes tecnologías facilitadoras para el desarrollo de aplicaciones para la navegación autónoma de plataformas robóticas en exteriores: Unity como motor de desarrollo, ROS para los mensajes de comunicación y OpenStreetMaps como software para procesamiento de mapas geográficos.
Jésuites et Herméneutique du Marxisme chinois
Authors: Vendé Yves 
Published: August 2024

The contribution begins by giving an account of the Jesuits’ relationship to philosophy – a relationship nourished by Thomism but not solely dependent on it. The Jesuit perspective is concerned with maintaining a balance between, on one hand, a unified vision of knowledge and human life, and an openness to developments in the world; and on the other hand, emphasizing the link between knowledge effort and moral transformation. This approach, anchored in the Greek tradition, guided the Jesuits in their encounter with Confucianism in the 17th century, leading to notable developments and particularly a “conversion” with neo-Confucianism. This interpretive framework was also applied against Marxism, involving various evaluations of the non-Thomist tradition. The remainder of this article explains how a historian of Chinese thought and comparative philosopher, Henri Bernard-Maître, developed an interpretation of Marxism as a resource meeting the expectations of Chinese youth in the 1930s. His successor, Octave Brière, adopts a more critical tone, whether describing the history of Chen Duxiu, the Communist Party, or the effects of Marxist thought with the central role of propaganda. Brière highlights the importance of characters, laws of evolution of history, practice, and the anthropological limits of the Marxist position. The last part of this article provides a counterpoint to the theoretical reflections with field reports from several missionaries present in Shanghai or in rural areas of the North. Ultimately, in the Jesuits’ engagement with Chinese Marxism, the main point of friction reveals itself to be the room left for the possibility of personal spiritual experience.
Cursos institucionales masivos: retos, experiencias y buenas prácticas
Authors: Schumacher Gagelmann Christian Tomás 
Published: August 2024

This article reports the experience of designing and implementing massive institutional, virtual courses aimed at the 23,000 employees of the Fiscalía General de la Nación, Colombia. Courses aimed at such a large and heterogeneous population present pedagogical and curricular challenges. How to design a course aimed at a non-academic audience? How to design contextually relevant courses? How to direct a course to a supremely heterogeneous audience? What role do these courses play in organizational learning? This article reflects on these challenges and the resulting good practices.
Spectrum of various histomorphological changes in heart studied with autopsy specimens - An institutional observational study
Authors: Barua Madhumita , Goswami Bidyut Krishna , Ganguly Soumik 
Published: August 2024

Regardless of the suspected cause of death, the post-mortem examination should always be done where deaths (related to sudden and unexpected demise), come under the jurisdiction to determine the cause and manner of the death. Various incidental findings are identified during microscopic examination which may or may not be the contributing factor for cause of death. This findings may have been a great learning tool for pathologists. So, an autopsy study of heart was conducted to find out the various histopathological changes. To study the spectrum of histomorphological changes in heart in autopsies. The study was conducted in the Department of Pathology, North Bengal medical college, West Bengal for a period of 2 years from August 2021 to August 2023. Total 143 autopsy specimen was received during this period, specimen of heart received were 139, 06 were autolysed. So 133 specimens of heart were examined macroscopically and microscopically to see the different histopathological findings. In our study most of the heart received in the age group of 21 -30 yrs. 72.1% cases showed fatty tissue interposition, 59.4% showed myocardial hypertrophy, 39.8% showed myocyte fibrosis, 31.57% showed inflammatory infiltration within myocyte, 22.5% showed atherosclerosis and thrombus within coronary vessels found in 6.7%. The most common finding in our study is fatty tissue interposition within myocyte which differs from previous studies which showed atherosclerosis as the most common findings.