bluuebunny/crossref_metadata_2025_split huggingface dataset:
Superior Enhancement in Mechanical Properties of Polyurethane‐Based Multifunctional GAP Partially Grafted with Fluorinated Polyether via Catalyst‐Free Click Reaction
Authors: Zhou Yanqiu , Peng Rufang , Jin Bo 
Published: August 2024

AbstractDifunctional glycidyl azide polymer (GAP) is an energetic binder promising for propellant formulations. The multifunctional fluorine‐containing GAP has been synthesized to enhance its mechanical properties. This work outlined multifunctional GAP partially grafted with 1,2,3‐triazole‐5‐(α‐hydroxyl)‐fluorinated polyether (GAP‐g‐3F) synthesized by thermal and catalyst‐free azide‐alkyne cycloaddition reaction, in which the azide groups were from GAP and electron‐deficient alkynes from β‐propargyl‐α‐hydroxyl poly (tri‐fluoropropane glycidyl ether) (PHP3F). PHP3F was synthesized via the typical cationic ring‐opening polymerization of 2‐((2,2,2‐trifluoroethoxy) methyl) oxirane and propargyl alcohol as the initiator. The chemical structures, molecular weight, and thermal properties were characterized by FTIR, NMR, GPC, DSC, and TGA, respectively. HNMR results showed that 8 % of total azide groups in GAP were grafted. GAP‐g‐3F had a slightly higher glass transition temperature than that of GAP. The results of TGA showed that GAP‐g‐3F had suitable thermal decomposition resistance up to 200 °C. The thermal properties, mechanical properties, cross‐linking network structures, and microstructures of the polyurethane networks cured with hexamethylene diisocyanate trimer as a crosslinking agent were determined and compared by TGA, universal tensile test, swelling measurement, and SEM, respectively. The initial decomposition temperature of GAP‐g‐3F‐based polyurethane networks (GAP‐g‐3F‐PU) was around 220 °C, thus meeting the requirements for propellants. In addition, GAP‐g‐3F‐PU exhibited superior mechanical properties, showing an almost twelvefold increase in tensile strength to 16.9 MPa compared with difunctional GAP‐PU with 1.4 MPa tensile strength. The results of the swelling measurement revealed that the GAP‐g‐3F‐PU sample showed a higher crosslinking density in comparison to the GAP‐PU sample. SEM results indicated that the multifunctional fluorine‐containing GAP could enhance compatibility between the soft and hard segments of polyurethanes, leading to a decrease in their separation degree. This finding showed that the synthesis of a multifunctional GAP partially grafted with fluorinated polyether via a triazole ring may be a promising solution to decrease the separation degree increase of PUs, thereby improving the mechanical properties.
Anti‐Phytopathogenic and Phytotoxic Effects of Annona glabra Lin. and Annona muricata Lin. Seed Extracts: In vitro and In vivo Assessment, Bioactive Compound Quantification, and Mechanism Involved
Authors: Le Dang Quang , Quoc Nguyen Cuong , De Tran Quang , Kim Jin‐Cheol , Thi Vo Kieu Anh , Thi Cao Hong , Thi Nguyen Xuyen , Huy Nguyen Trung , Thi Nguyen Thu Trang , Huu Nguyen Tung , Tu Ho Cuong , Thanh Nguyen Cong , Tam Le The , Son Nguyen Vu , Ja Choi Gyung 
Published: August 2024

AbstractBuilding upon prior research demonstrating the excellent antifungal and nematicidal efficacy of Annona squamosa Lin. seed extracts, this study extends its scope to investigate similar properties in seed extracts from two other Annonaceae species: Annona muricata Lin. and Annona glabra Lin. The focus is on assessing their effectiveness against tomato late blight (TLB) and wheat leaf rust (WLR) diseases, as well as their broader antifungal activity against Colletotrichum sp. and Fusarium sp. The A. glabra seed extract exerted a superior control efficacy against TLB (85 % at 62.5 μg/mL) and WLR (75 % at 125 μg/mL) in vivo. The two Annonaceous extracts also exhibited in vitro antifungal inhibition against Colletotrichum sp. and Fusarium sp., as well as toxicology against pine wilt nematodes and Artemia salina. Besides, they showed phytotoxicity against Raphanus sativus seed germination. Squamocin G, a potent bioactive acetogenin, was isolated from A. glabara, which was found to occur at high contents in the following ascending order in A. glabra, A. muricata and A. squamosa dichloromethane extracts. To investigate the antifungal mechanism, molecular docking and molecular dynamic of squamocin G ligand were also performed for the first time at the active site of succinate dehydrogenase and β‐tubulin.
Noble Metal‐Free High Entropy Perovskite Oxide with High Cationic Dispersion Enhanced Oxygen Redox Reactivity
Authors: Chatterjee Arindam , Ganguly Dipsikha , Sundara Ramaprabhu , Bhattacharya Subramshu S. 
Published: August 2024

AbstractHigh entropy perovskite oxide (HEPO) materials have received significant interest as efficient electrocatalysts owing to their chemical and structural stability, effective interaction of multiple metal active sites with the reaction intermediate species resulting in enhanced catalytic activity. The effect of high‐entropy strategy could achieve the regulation of the structural durability by tailoring the composition. Herein, we design a novel transition metal and rare‐earth metal based high entropy perovskite oxide (Co0.11Mn0.11Ni0.11Fe0.14La0.13Nd0.13Gd0.13Pr0.13)O3, showing superior catalytic activity in the oxygen reduction reaction (ORR) and also promising electrocatalyst in oxygen evolution reaction (OER). High degree of cationic dispersion in the lattice and multiple electrocatalytic active sites enhance the oxygen ion migration at the surface and facilitate electron transfer, manifesting good ORR performance. Notably, the as‐prepared high entropy material exhibits onset and half‐wave potential of 1.02 V and 0.89 V versus RHE, respectively, exceeding the performance of the benchmarked Pt/C catalyst in the ORR process with reasonable redox kinetics. Moreover, the material also presents faster kinetics with reasonably low overpotential and excellent electrochemical stability in the OER process as well. This study shows the viability of designing non‐precious high entropy materials as highly efficient oxide electrocatalyst by utilizing its broad compositional space.
Iron‐Catalyzed Vinylogous Michael Addition of Boron Dipyrromethene (BODIPY) Derivatives to para‐Quinone Methides
Authors: Li Chaofan , Yuan Changxian , Wang Xu , Guo Qinghua , Liu Biao , Wang Sinan , Zhang Zhiguang , Gao Jinlong , Zhai Pengda , Zhang Yong 
Published: August 2024

AbstractWe report herein an effective method for an iron‐catalyzed vinylogous Michael addition of BODIPY derivatives to para‐quinone methides under mild conditions. The corresponding BODIPY‐derived diarylmethane compounds were obtained in 65–93 % yields. This method is featured by its inexpensive catalyst, simple reaction condition and broad substrate scope.
Comparative Study on Silver Nanoparticle Synthesis Using Male and Female Pistacia Khinjuk Leaf Extracts: Enhanced Efficacy of Female Leaf Extracts
Authors: Tural Bilsen , Ertaş Erdal , Batıbay Hayri , Tural Servet 
Published: August 2024

AbstractThis study aims to uncover the potential differences in bioactive compounds present in leaf extracts obtained from female and male individuals of Pistacia khinjuk, abundantly found in the Southeast Anatolia region of Turkey, and their roles in influencing the properties of synthesized silver nanoparticles (AgNPs). Results obtained through TEM and SEM imaging techniques determined the morphology and size of AgNPs synthesized from female (FL‐AgNPs) and male (ML‐AgNPs) leaf extracts. Additionally, FTIR spectrum analysis demonstrated the chemical composition of the FL‐AgNPs, ML‐AgNPs, and the extracts. Zeta potential and zeta sizer analyses revealed differences between nanoparticles obtained from female and male plants. The total phenolic content of leaf extracts from female plants is significantly higher than that obtained from male plants (female plants: 30.68±0.26 mg GAE/g, male plants: 24.22±0.37 mg GAE/g). Furthermore, FL‐AgNPs (43.2±2.64 mg GAE/g) exhibit higher antioxidant activity compared to ML‐AgNPs (31.7±1.16 mg GAE/g). ICP‐MS analyses indicate that FL‐AgNPs are synthesized with higher efficiency compared to ML‐AgNPs (FL‐AgNPs: 99.90±0.106 %, ML‐AgNPs: 94.99±0.079 %). Finally, the antibacterial efficacy of FL‐AgNPs and ML‐AgNPs nanoparticles was evaluated agar well diffusion method against the pathogen Escherichia coli (E.Coli) and Staphylococcus aureus (S. Aureus]
Base Mediated Formal [2+4] Annulation of 3‐Hydroxyoxindoles with 1,2‐Bis(bromomethyl)benzene: Access to Spirooxindole‐Fused Oxacycles
Authors: Feng Jiaxu , Yang Bingyu , Wang Xiangdi , Wu Yingying , Wang Shiqiang , Li Yuming , Fan Zhi 
Published: August 2024

AbstractHere a base‐mediated formal [2+4] annulation of 3‐hydroxyoxindoles with 1,2‐bis(bromomethyl)benzene have been accomplished, affording spirooxindole‐fused oxacycles in good yields. This protocol features great functional group tolerance in mild reaction conditions. Gram‐scale synthesis and further transformation have also been demonstrated.
Rod‐Shaped Au@Ce Nano‐Platforms for Enhancing Photodynamic Tumor Collaborative Therapy
Authors: Sun Yuxiang , Cao Ziqi , Zhang Xiaoli , Zhu Xingchen , Xu Zhenyang , Zhou Hantong , Wei Xiaoer , Du Wenxian , Xu Li 
Published: August 2024

AbstractTumor photodynamic therapy (PDT) relies on intratumoral free radicals, while the limited oxygen source and the depletion of tissue oxygen may exacerbate the hypoxia. As the treatment progresses, there will eventually be a problem of insufficient free radicals. Here, it is found that Au@CeO2 nano‐rods (Au@Ce NRs), assembled by gold nano‐rods (Au NRs) and ceria nanoparticles (CeO2 NPs), can efficaciously absorb near‐infrared light (NIR) to promote the release of oxygen and free radicals. Au@Ce NRs exhibit a higher proportion of Ce3+ (Ce2O3) after oxygen release, while Ce3+ is subsequently oxidized to Ce4+ (CeO2) by trace H2O2. Interestingly, Au@Ce NRs re‐oxidized by trace H2O2 can re‐release oxygen and free radicals again upon NIR treatment, achieving oxygenation/oxygen evolution, similar to charging/discharging. This loop maximizes the conversion of limited oxygen source into highly cytotoxic free radicals. As a result, when B16‐F10 cells are treated by NIR/Au@Ce NRs, more tumor cells undergo apoptosis, consistent with the higher level of free radicals. Importantly, NIR/Au@Ce NRs successfully suppresses tumor growth and promotes the generation of epidermal collagen fibers in the transplanted tumor model. Therefore, the rod‐shaped Au@Ce NRs provide an ideal platform for maximizing the utilization of intratumoral oxygen sources and improving the treatment of melanoma.
A lightweight security defense algorithm for multimodal attack blocking in industrial control networks based on momentum enhanced feature graphs
Authors: Yang Zhenyong , Gao Changzhong , Wang Yong , Meng Hailong , Han Shicong 
Published: August 2024

AbstractAs the infrastructure of modern industry, the safe and stable operation of lightweight industrial control network is crucial for industrial production. Multi‐mode attack is a kind of highly customized and low resource consumption network attack method, which can target the specific vulnerabilities and configuration weaknesses of lightweight industrial control network. In order to improve the defense capability of industrial control network against multimodal attacks, a lightweight security defense algorithm based on momentum‐enhanced feature graph is proposed. The lightweight industrial control network operation mode is determined by abstract relationship, and the ontology structure of industrial control network multi‐mode attack is established; with reference to the ontology structure, the multi‐mode attack map of industrial control network is defined; the normal behavior and lightweight attack behavior are divided, and the convolutional network is used to enhance the characteristics of lightweight attack; and the momentum‐enhanced feature map technology is used to correspond to the enhancement process, and to block and defend against the multi‐mode attack of industrial control network. The results show that the studied algorithm can realize accurate prediction of attack behaviors with different attack behaviors as test objects, and ensure accurate blocking of all kinds of attack behaviors with better security defense effect.
A deep experimental analysis of energy‐proficient firewall policies and security practices for resource limited wireless networks
Authors: Rajasoundaran S. , Sivakumar S. A. , Devaraju S. , Pasha M. Jahir , Lloret Jaime 
Published: August 2024

AbstractThe role of firewalls and security principles in resource‐limited wireless networks and Wireless Sensor Networks (WSN) is more expected than in any dedicated network environment. The advanced wireless technologies and emerging fashion of autonomous wireless network nodes are mostly expecting resilient firewall services with multi‐level security policies. Wireless networks are classified under sensor networks, Internet of Things (IoT) mobile networks, and so forth. According to the expectations, security frameworks are gradually invented around the communication platform using various ideologies. The novel ideology and respective implementation effort open better solutions against wireless network attacks. Anyhow, the minimal production of time complexity, energy complexity, and computation overhead from any novel security approach is always considered under the best practices. The complexity levels directly affect the wireless node's energy consumption ability and operational spans severely. The energy optimization techniques and load‐balancing techniques integrated into multi‐class firewall rules are extremely useful solutions for resource‐limited wireless networks. This article has been motivated to analyze the recent firewall techniques and secure data communication mechanisms used for securing wireless networks. Consequently, the practice of comparative literature analysis helps to improve the current limitations identified under the classified categories of security mechanisms such as energy‐optimized security principles and load‐balanced security principles. The establishment of secure and energy‐optimized multi‐class firewall rules in each wireless node assures a healthy focus on next‐generation networks. The experiment section shows the benefits of energy‐optimized secure network communication in terms of better accuracy and the benefits of load‐balanced secure network communication through minimal overhead in computing platforms.
Translational evaluation of Gelsectan® effects on gut barrier dysfunction and visceral pain in animal models and irritable bowel syndrome with diarrhoea
Authors: Inczefi Orsolya , Eutamene Hélène , Placide Fanny , Tondereau Valérie , Pallagi Petra , Bagyánszki Mária , Bódi Nikolett , Gémes Nikolett , Szebeni Gábor , Molnár Tamás , Theodorou Vassilia , Róka Richárd 
Published: August 2024

AbstractBackgroundGelsectan® is a formulation of xyloglucan (XG), pea protein, grape seed extract (PPGS) and xylo‐oligosaccharides (XOS). Our aim was to examine the effect of Gelsectan® on rectal sensitivity in an animal model, abdominal pain in irritable bowel syndrome with diarrhoea (IBS‐D) subjects and intestinal permeability in both conditions.MethodsAnimals: Wistar rats received gavage with XOS, XG + PPGS or XG + PPGS + XOS, as a single dose or for 7 days before a partial restraint stress (PRS). Visceromotor response to rectal distension and total gut paracellular permeability to 51Cr‐EDTA were assessed. Humans: IBS‐D and control patients were involved. After initial colonoscopy with biopsy sampling Gelsectan® was administered to IBS‐D patients for 12 weeks. Stool count and pain scores were documented. After treatment, colonoscopy was repeated. The permeability of biopsy samples was measured in Ussing‐chambers. Adherent mucus layer, Muc‐2 expression as well as TNFα, Interferon IFNγ were evaluated by histology/immunohistochemistry and ELISA assays, respectively.ResultsAnimal studies: In control rats, PRS significantly increased visceromotor response as well as gut paracellular permeability. Single dose administration of XG + PPGS + XOS failed to reverse PRS, but 7 days of oral treatment reversed PRS‐induced rectal hypersensitivity and gut hyperpermeability. Human studies: Gelsectan® treatment significantly reduced and abdominal pain. Intestinal permeability in IBS‐D patients was elevated compared with controls, Gelsectan® restored permeability in the ascendent colon. Periodic acid–Schiff‐stained mucus layer was significantly thinner in IBS‐D patients compared with controls, In both segments, mucus thickness and the proportion of Muc‐2 positive cells were not affected by Gelsectan® treatment. IFNγ tissue level in the sigmoid colon shows modest mucosal inflammation in IBS‐D.ConclusionsGelsectan® prevented rectal hypersensitivity in rats, abdominal pain in human and intestinal hyperpermeability in rat and human studies respectively. These effects involve restoration of gut permeability. Based on this translational study, Gelsectan® can be considered as an effective therapy for IBS‐D symptoms.
Medical intelligence for anxiety research: Insights from genetics, hormones, implant science, and smart devices with future strategies
Authors: Akhtar Faijan , Belal Bin Heyat Md , Sultana Arshiya , Parveen Saba , Muhammad Zeeshan Hafiz , Merlin Stalin Fathima , Shen Bairong , Pomary Dustin , Ping Li Jian , Sawan Mohamad 
Published: August 2024

AbstractThis comprehensive review article embarks on an extensive exploration of anxiety research, navigating a multifaceted landscape that incorporates various disciplines, such as molecular genetics, hormonal influences, implant science, regenerative engineering, and real‐time cardiac signal analysis, all while harnessing the transformative potential of medical intelligence [medical + artificial intelligence (AI)]. By addressing fundamental research questions, this study investigated the molecular and hormonal foundations underlying anxiety disorders, shedding light on the intricate interplay of genetic and hormonal factors contributing to the etiology and progression of anxiety. Furthermore, this review delves into the emerging implications of biomaterials, defibrillators, and state‐of‐the‐art devices for anxiety research, elucidating their potential roles in diagnosis, treatment, and patient management. A pivotal contribution of this review is the development and exploration of an AI‐driven model for real‐time cardiac signal analysis. This innovative approach offers a promising avenue for enhancing the precision and timeliness of anxiety diagnosis and monitoring. Leveraging machine learning and AI techniques enables the accurate classification of persons with anxiety based on real‐time cardiac data, thereby ushering in a new era of personalized and data‐driven mental health care. Identifying emerging themes and knowledge gaps lays the foundation for future research directions and offers a roadmap for scholars and practitioners to navigate this intricate field. In conclusion, this comprehensive review serves as a vital resource, consolidating diverse perspectives and fostering a deeper understanding of anxiety disorders from biological, engineering, and technological standpoints, ultimately contributing to advancing mental health research and clinical practice.This article is categorized under:
Application Areas > Health Care
Application Areas > Science and Technology
Technologies > Classification
Adding stubs to quantum string field theories
Authors: Maccaferri C. , Poletti R. , Ruffino A. , Valsesia B. 
Published: August 2024

Abstract
Generalizing recent work by Schnabl-Stettinger and Erbin-Fırat, we outline a universal algebraic procedure for ‘adding stubs’ to string field theories obeying the BV quantum master equation. We apply our results to classical and quantum closed string field theory as well as to open-closed string field theory. We also clarify several aspects of the integration-out process in the co-algebraic formulation of string field theory at the quantum level.
A convergence theorem for Crandall–Lions viscosity solutions to path-dependent Hamilton–Jacobi–Bellman PDEs
Authors: Criens David 
Published: August 2024

AbstractWe establish a convergence theorem for Crandall–Lions viscosity solutions to path-dependent Hamilton–Jacobi–Bellman PDEs. Our proof is based on a novel convergence theorem for dynamic sublinear expectations and the stochastic representation of viscosity solutions as value functions.
A “Self-Milieux” perspective on help-seeking: examining the impact of a person’s sociocultural background on help-seeking in people with untreated depressive symptoms
Authors: McLaren Thomas , Peter Lina-Jolien , Tomczyk Samuel , Muehlan Holger , Schomerus Georg , Schmidt Silke 
Published: August 2024

Abstract

Background
Mental illness is a global concern and the leading cause of years lived with disability. Research on help-seeking behaviour has focused on individual factors, but there is still much unexplained variance. Suggesting complex interactions between determinants of human behaviour a new framework called Self-Milieux is proposed to represent a person’s sociocultural background. The article introduces a statistical approach to determine Self-Milieux and exemplarily examines its predictive validity for health-related research.

Methods

Self-Milieux are determined through a two-stage clustering method based on the determinants socioeconomic status and self-construal profile. Descriptive analyses are used to compare Self-Milieux characteristics. Hierarchical binary logistic regression models test the association between Self-Milieux and help-seeking behaviour, while controlling for socioeconomic status as an established predictor.

Results
The sample size was N = 1535 (M

age
= 43.17 and 64.89% female participants). Average depression severity was M = 12.22, indicating mild to moderate symptoms. Six Self-Milieux were determined and named. Participants from privileged (aOR = 0.38) and self-sufficient (aOR = 0.37) milieux were less likely to seek help from a general practitioner than those from the entitled milieu. Participants from privileged (aOR = 0.30), collaborators (aOR = 0.50), disadvantaged (aOR = 0.33), and self-sufficient (aOR = 0.21) milieux were less likely to seek help from family members than those from the entitled and family-bound milieux.

Discussion
The study’s strengths and limitations, as well as the cluster methodology, are discussed. The comparative results for the six Self-Milieux are interpreted based on current research. For example, participants from some milieux follow a help-seeking process proposed in previous research, while participants from other milieux seem to show a different process, one that ends in informal help-seeking.