bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of Adding an Internet-Based Pain Coping Skills Training Protocol to a Standardized Education and Exercise Program for People With Persistent Hip Pain (HOPE Trial): Randomized Controlled Trial Protocol
Authors: Bennell Kim L. , Rini Christine , Keefe Francis , French Simon , Nelligan Rachel , Kasza Jessica , Forbes Andrew , Dobson Fiona , Haxby Abbott J. , Dalwood Andrew , Vicenzino Bill , Harris Anthony , Hinman Rana S. 
Published: May 2015

Background
Persistent hip pain in older people is usually due to hip osteoarthritis (OA), a major cause of pain, disability, and psychological dysfunction.

Objective
The purpose of this study is to evaluate whether adding an Internet-based pain coping skills training (PCST) protocol to a standardized intervention of education followed by physical therapist–instructed home exercise leads to greater reductions in pain and improvements in function.

Design
An assessor-, therapist-, and participant-blinded randomized controlled trial will be conducted.

Setting
The study will be conducted in a community setting.

Participants
The participants will be 142 people over 50 years of age with self-reported hip pain consistent with hip OA.

Intervention
Participants will be randomly allocated to: (1) a control group receiving a 24-week standardized intervention comprising an 8-week Internet-based education package followed by 5 individual physical therapy exercise sessions plus home exercises (3 times weekly) or (2) a PCST group receiving an 8-week Internet-based PCST protocol in addition to the control intervention.

Measurements
Outcomes will be measured at baseline and 8, 24, and 52 weeks, with the primary time point at 24 weeks. Primary outcomes are hip pain on walking and self-reported physical function. Secondary outcomes include health-related quality-of-life, participant-perceived treatment response, self-efficacy for pain management and function, pain coping attempts, pain catastrophizing, and physical activity. Measurements of adherence, adverse events, use of health services, and process measures will be collected at 24 and 52 weeks. Cost-effectiveness will be assessed at 52 weeks.

Limitations
A self-reported diagnosis of persistent hip pain will be used.

Conclusions
The findings will help determine whether adding an Internet-based PCST protocol to standardized education and physical therapist–instructed home exercise is more effective than education and exercise alone for persistent hip pain. This study has the potential to guide clinical practice toward innovative modes of psychosocial health care provision.
Les Antigonides avaient-ils des cornes ? Sur l’utilisation d’un attribut divin dans les représentations d’une dynastie hellénistique
Authors: Barre Romain 
Published: May 2015

Avec l’éclatement de l’empire d’Alexandre le Grand apparaît le morcellement du pouvoir et les souverains qui prennent sa suite se livrent à une intense concurrence. Leur rivalité ne s’exprime pas uniquement sur le champ de bataille mais ils s’affrontent aussi par le biais de leur mode de représentation. Les attributs qu’ils choisissent sont donc lourds de sens, et c’est ainsi qu’il convient de les analyser. Dans le cas de la dynastie des Antigonides, un attribut semble tenir une place particulière : les cornes, en ce qu’elles font référence aux succès militaires des souverains, sont un élément décisif quant à l’identification des portraits des rois antigonides.
Twist1 and Twist2 Contribute to Cytokine Downregulation following Chronic NOD2 Stimulation of Human Macrophages through the Coordinated Regulation of Transcriptional Repressors and Activators
Authors: Zheng Shasha , Hedl Matija , Abraham Clara 
Published: May 2015

Abstract
Proper regulation of microbial-induced cytokines is critical to intestinal immune homeostasis. Acute stimulation of nucleotide-binding oligomerization domain 2 (NOD2), the Crohn’s disease–associated sensor of bacterial peptidoglycan, induces cytokines. However, chronic NOD2 stimulation in macrophages decreases cytokines upon pattern recognition receptor (PRR) restimulation; cytokine attenuation to PRR stimulation is similarly observed in intestinal macrophages. The role for the transcriptional repressors Twist1 and Twist2 in regulating PRR-induced cytokine outcomes is poorly understood and has not been reported for NOD2. We found that Twist1 and Twist2 were required for optimal cytokine downregulation during acute and, particularly, chronic NOD2 stimulation of human macrophages. Consistently, Twist1 and Twist2 expression was increased after chronic NOD2 stimulation; this increased expression was IL-10 and TGF-β dependent. Although Twist1 and Twist2 did not coregulate each other’s expression, they cooperated to enhance binding to cytokine promoters after chronic NOD2 stimulation. Moreover, Twist1 and Twist2 contributed to enhance expression and promoter binding of the proinflammatory inhibitor c-Maf and the transcriptional repressor Bmi1. Restoring c-Maf and Bmi1 expression in Twist-deficient macrophages restored NOD2-induced cytokine downregulation. Furthermore, with chronic NOD2 stimulation, Twist1 and Twist2 contributed to the decreased expression and cytokine promoter binding of the transcriptional activators activating transcription factor 4, C/EBPα, Runx1, and Runx2. Knockdown of these transcriptional activators in Twist-deficient macrophages restored cytokine downregulation after chronic NOD2 stimulation. Finally, NOD2 synergized with additional PRRs to increase Twist1 and Twist2 expression and Twist-dependent pathways. Therefore, after chronic NOD2 stimulation Twist1 and Twist2 coordinate the regulation of both transcriptional activators and repressors, thereby mediating optimal cytokine downregulation.
Specific Contributions of CSF-1 and GM-CSF to the Dynamics of the Mononuclear Phagocyte System
Authors: Louis Cynthia , Cook Andrew D. , Lacey Derek , Fleetwood Andrew J. , Vlahos Ross , Anderson Gary P. , Hamilton John A. 
Published: May 2015

Abstract
M-CSF (or CSF-1) and GM-CSF can regulate the development and function of the mononuclear phagocyte system (MPS). To address some of the outstanding and sometimes conflicting issues surrounding this biology, we undertook a comparative analysis of the effects of neutralizing mAbs to these CSFs on murine MPS populations in the steady-state and during acute inflammatory reactions. CSF-1 neutralization, but not of GM-CSF, in normal mice rapidly reduced the numbers of more mature Ly6C− monocytes in blood and bone marrow, without any effect on proliferating precursors, and also the numbers of the resident peritoneal macrophages, observations consistent with CSF-1 signaling being essential only at a relatively late state in steady-state MPS development; in contrast, GM-CSF neutralization had no effect on the numbers of these particular populations. In Ag-induced peritonitis (AIP), thioglycolate-induced peritonitis, and LPS-induced lung inflammation, CSF-1 neutralization lowered inflammatory macrophage number; in the AIP model, this reduced number was not due to suppressed proliferation. More detailed studies with the convenient AIP model indicated that CSF-1 neutralization led to a relatively uniform reduction in all inflammatory cell populations; GM-CSF neutralization, in contrast, was more selective, resulting in the preferential loss among the MPS populations of a cycling, monocyte-derived inflammatory dendritic cell population. Some mechanistic options for the specific CSF-dependent biologies enumerated are discussed.
The history of the interpretation of Matthew: Lessons learned
Authors: Allison Dale C. 
Published: May 2015

Scholars pay attention to the history of interpretation of biblical texts and of their reception for multiple good reasons. This essay urges that, in addition to the reasons typically offered, careful Wirkungsgeschichte can sometimes bring to light credible exegetical and historical proposals that were once in the commentary tradition but dropped out for no apparent or good reason. Such proposals need to be restored to the tradition. I shall offer several illustrations, including the old association of Matthew 5:21–26 with the sacrifice of Cain and Abel and the ancient linking of Matthew 9:20–21 and 14:36 with the prophecy of Malachi 4:2 (‘The Son of Righteousness will arise with healing in his wings’). The article also, however, draws attention to some of the limitations of Wirkungsgeschichte for historical exegesis. Die interpretasiegeskiedenis van Matteus: Lesse geleer. Navorsers skenk aan die interpretasiegeskiedenis van bybelse tekste en die ontvangs van die verskillende tekste omverskeie redes aandag. Hierdie artikel toon aan dat, behalwe vir redes wat normaalweg aangebied word, ’n noukeurige ‘Wirkungsgeschichte’ soms geloofwaardige eksegetiese en historiese voorstelle na vore kan bring wat tevore wel tot die kommentaretradisie behoort het, maar gaandeweg in onbruik verval het. Sodanige voorstelle behoort weer tot die tradisie toegevoeg te word. Ter stawing hiervan kan verskeie voorbeelde genoem word soos die bekende assosiasie van Matteus 5:21–26 met die offer van Kain en Abel en die oeroue koppeling van Matteus 9:20–21 en 14:36 met die profesie van Maleagi 4:2 (‘Die son van geregtigheid salverrys met genesing in sy vleuels’). Hierdie artikel vestig egter ook die aandag op sekere beperkings van die ‘Wirkungsgeschichte’ vir die historiese eksegese.
Computational Study of Nonadiabatic Wave Patterns in Smouldering Combustion under Microgravity
Authors: Ijioma Ekeoma Rowland , Izuhara Hirofumi , Mimura Masayasu , Ogawa Toshiyuki 
Published: May 2015

AbstractWe numerically study a thermal-diffusive model for smouldering combustion under microgravity with convective heat losses. In accordance with previous experimental observations, it is well known that porous materials burning against a gaseous oxidiser under microgravity exhibit various finger-like char patterns due to the destabilising effect of oxidiser transport. There is a close resemblance between the pattern-forming dynamics observed in the experiments with the mechanism of thermal-diffusive instability, similar to that occurring in low Lewis number premixtures. At large values of the Lewis number, the finger-like pattern coalesces and propagates as a stable front reminiscent of the pattern behaviour at large Péclet numbers in diffusion-limited systems. The significance of the order of the chemical kinetics for the coexistence of both upstream and downstream smoulder waves is also considered.
A Multigrid Solver based on Distributive Smoother and Residual Overweighting for Oseen Problems
Authors: Chen Long , Hu Xiaozhe , Wang Ming , Xu Jinchao 
Published: May 2015

AbstractAn efficient multigrid solver for the Oseen problems discretized by Marker and Cell (MAC) scheme on staggered grid is developed in this paper. Least squares commutator distributive Gauss-Seidel (LSC-DGS) relaxation is generalized and developed for Oseen problems. Residual overweighting technique is applied to further improve the performance of the solver and a defect correction method is suggested to improve the accuracy of the discretization. Some numerical results are presented to demonstrate the efficiency and robustness of the proposed solver.
Opportunities for Improved Fire Use and Management in California: Lessons from Western Australia
Authors: Sneeuwjagt Rick J. , Kline Tim S. , Stephens Scott L. 
Published: May 2015

AbstractAs the large scale of fuel treatments needed to promote ecosystem health and reduce heavy fuel loads becomes clear in California’s mixed conifer forests, managers are beginning to focus on how to scale up prescribed fire use in order to treat a meaningful portion of the landscape. We look at the example of Western Australia’s large-scale and highly successful prescribed burning program by their Department of Environment and Conservation as a model for emulation by land management agencies in California. Focusing on: 1) novel management practices, 2) inter-agency collaboration, 3) regulatory collaboration and policy, 4) research integration, 5) cultural acceptance, and 6) political support of prescribed fire, we make recommendations for a new approach to the management and regulation of fire use in California’s mixed conifer forests.
Creating Hotter Fires in the Sonoran Desert: Buffelgrass Produces Copious Fuels and High Fire Temperatures
Authors: McDonald Christopher J. , McPherson Guy R. 
Published: May 2015

AbstractBuffelgrass (Pennisetum ciliare [L.] Link) can create a grass-fire cycle in many parts of the world because it is a highly competitive, fire-tolerant grass and can replace less fire-tolerant native plants. Fuel loads, loss of buffelgrass biomass after herbicide treatments, and allometric data of buffelgrass growth were measured across sites in southern Arizona, USA. Prescribed fires also were conducted in buffelgrass-dominated fields to measure fire temperatures and quantify relationships between temperature and fuel load. We directly recorded temperatures up to 871 °C and indirectly recorded temperatures of 900 °C. There was no relationship between fuel load and temperature, likely because increased fuel was insufficient to contribute to additional fire intensity beyond minimum fuel loads. Compared to previously described buffelgrass stands and across different desert ecosystems, buffelgrass fuel loads were higher than reported in most other studies, and inter-annual variation in buffelgrass biomass is much lower than that of other invasive grasses, including annual and perennial grasses. As a result, buffelgrass creates a more consistent year-to-year fire hazard than annual grasses. Managers have used herbicide to reduce buffelgrass biomass and we found that, after three years of decomposition, stands of dead buffelgrass were unlikely to support fire spread. Allometric relationships can provide an accurate estimate of buffelgrass biomass of individual plants, but not fuel loads. Buffelgrass produces nonnative grasslands at relatively low elevations of the Sonoran Desert, with more biomass than comparable grasslands in more mesic environments.
Relative Bark Thickness is Correlated with Tree Species Distributions along a Fire Frequency Gradient
Authors: Schafer Jennifer L. , Breslow Bradley P. , Hohmann Matthew G. , Hoffmann William A. 
Published: May 2015

AbstractThe probability of stem survival after fire is strongly influenced by energy allocation to bark because bark thickness affects heat transfer during fire. Greater relative investment in inner bark versus outer bark should also enhance survival because of greater moisture content of inner bark. We measured stem diameter, bark thickness, and habitat preference of five species typical of long-leaf pine savannas, and six species characteristic of adjacent wetlands (pocosins), and calculated relative bark thickness, the inner bark proportion, radial growth, and bark accumulation of each species. We hypothesized that savanna species have thicker bark and greater relative investment in inner bark than pocosin species, because fires occur more frequently in savannas than pocosins. As hypothesized, savanna species have relatively thicker bark than pocosin species. Relative bark thickness and the rate of bark accumulation were correlated with the mean location of a species along the pocosin-to-savanna gradient. However, the inner bark proportion did not differ between savanna and pocosin species. Our results indicate that relative bark thickness is likely the primary bark trait affecting fire-induced topkill and influencing the distribution of species along the pocosin-to-savanna gradient.
Statistical convergence of double sequences on probabilistic normed spaces defined by $[ V, \lambda, \mu ]$-summability
Authors: Kumar Pankaj , Bhatia S. S. , Kumar Vijay 
Published: May 2015

In this paper, we aim to generalize the notion of statistical convergence for double sequences on probabilistic normed spaces with the help of two nondecreasing sequences of positive real numbers $\lambda=(\lambda_{n})$ and $\mu = (\mu_{n})$ such that each tending to zero, also $\lambda_{n+1}\leq \lambda_{n}+1, \lambda_{1}=1,$ and $\mu_{n+1}\leq \mu_{n}+1, \mu_{1}=1.$ We also define generalized statistically Cauchy double sequences on PN space and establish the Cauchy convergence criteria in these spaces.
Les musées de sciences, la « présence » des objets et les défis pédagogiques de l’habitus
Authors: Gauvin Jean-François 
Published: May 2015

L’objectif de ce texte est de jeter les bases théoriques et pratiques pour la création d’une approche complémentaire à la visite conventionnelle des musées de sciences et de techniques. Le point de vue proposé cherche à (re)centrer, à (re)focaliser encore plus la pédagogie et la didactique muséale sur l’objet. Comment, en effet, redonner à ces objets froids et inertes, généralement placés derrière d’austères vitrines, leur « présence » originelle, qui éveillera en nous non seulement le sens de la vue (la « beauté » esthétique et pratique de l’objet), mais tous les autres, sans lesquels les objets de notre quotidien perdent toute leur signification – leur sens. La clé d’analyse se trouve dans trois concepts : profondeur, procédé et participation. Et au coeur de ces concepts se cache l’habitus, l’apprentissage structuré et structurant de toute connaissance.
Les origines du Groupe d’intérêt spécialisé en éducation muséale (GISEM) dans la perspective de l’histoire de l’éducation muséale au Québec
Authors: Allard Michel 
Published: May 2015

L’ouverture du Muséum central des arts de la République (Louvre) au grand public parisien, en 1793, symbolise la volonté que le musée devienne un lieu voué à l’éducation. Dans la première moitié du 19e siècle, au Québec, on retrouve trois catégories de musée : ceux dits de divertissement; ceux dits savants, fondés par des sociétés scientifiques, artistiques ou historiques dont la plupart organisent des activités éducatives réservées à leurs membres; les musées dits didactiques, situés surtout dans des établissements scolaires. Ces derniers musées connaissent au 19e siècle une période d’expansion, suivie cent ans plus tard d’un déclin. À l’inverse, les musées savants organisent de plus en plus d’activités éducatives à l’intention d’un public de plus en plus diversifié. Le Musée des beaux-arts qui, en 1961, est devenu le premier musée savant québécois à mettre en place un service éducatif apparaît comme un pionnier. C’est dans ce contexte que seront mises sur pied dans les universités montréalaises des équipes de recherches axées sur le développement d’une pédagogie propre au musée ou sur le comportement des visiteurs. Ces groupes de recherche fonderont dans le cadre des sociétés savantes un groupe d’intérêt sur l’éducation muséale où les chercheurs mettent en commun le fruit de leurs travaux.
Les temporalités climatiques des paysages d’hiver hollandais
Authors: Metzger Alexis 
Published: May 2015

L’essor de la peinture hollandaise est une des facettes les plus riches du Siècle d’or. Au sein de cette profusion picturale, s’interroger sur les temporalités des paysages d’hiver apparaît porteur de réflexions pertinentes, aussi bien méthodologiques que conceptuelles. Il s’agira dans cet article d’analyser ces temporalités à travers des types de représentations picturales hollandaises, appartenant à un territoire à peu près homogène pour le climat, identifié politiquement et socialement au XVIIe siècle.En premier lieu, ces peintures s’inscrivent enfin dans une temporalité climatique pluriséculaire, le petit âge glaciaire (vers 1300-1860). L’autre pas de temps à analyser est celui de la saison hivernale. Enfin, un pas de temps très court correspondant à la journée, au temps qu’il fait, sera interrogé. Assurément, ces différentes temporalités sont imbriquées car certains types de temps appartiennent à l’hiver, qui est particulièrement long et froid au petit âge glaciaire.
Similarity in Difference
Authors: Lundh Christer , Kurosu Satomi 
Published: May 2015

A study of marriage in preindustrial Europe and Asia that goes beyond the Malthusian East–West dichotomy to find variation within regions and commonality across regions.
Since Malthus, an East–West dichotomy has been used to characterize marriage behavior in Asia and Europe. Marriages in Asia were said to be early and universal, in Europe late and non-universal. In Europe, marriages were supposed to be the result of individual choices but, in Asia, decided by families and communities. This book challenges this binary taxonomy of marriage patterns and family systems. Drawing on richer and more nuanced data, the authors compare the interpretations based on aggregate demographic patterns with studies of individual actions in local populations. Doing so, they are able to analyze simultaneously the influence on marriage decisions of individual demographic features, socioeconomic status and composition of the household, and local conditions, and the interactions of these variables. They find differences between East and West but also variation within regions and commonality across regions.
The book studies local populations in Sweden, Belgium, Italy, Japan, and China. Rather than a simple comparison of aggregate marriage patterns, it examines marriage outcomes and determinants of local populations in different countries using similar data and methods. The authors first present the results of comparative analyses of first marriage and remarriage and then offer chapters each of which is devoted to the results from a specific country. Similarity in Difference is the third in a prizewinning series on the demographic history of Eurasia, following Life under Pressure (2004) and Prudence and Pressure (2009), both published by the MIT Press.
Ostension
Authors: Engelland Chad 
Published: May 2015

An examination of the role of ostension—the bodily manifestation of intention—-in word learning, and an investigation of the philosophical puzzles it poses.
Ostension is bodily movement that manifests our engagement with things, whether we wish it to or not. Gestures, glances, facial expressions: all betray our interest in something. Ostension enables our first word learning, providing infants with a prelinguistic way to grasp the meaning of words. Ostension is philosophically puzzling; it cuts across domains seemingly unbridgeable—public–private, inner–outer, mind–body. In this book, Chad Engelland offers a philosophical investigation of ostension and its role in word learning by infants.
Engelland discusses ostension (distinguishing it from ostensive definition) in contemporary philosophy, examining accounts by Quine, Davidson, and Gadamer, and he explores relevant empirical findings in psychology, evolutionary anthropology, and neuroscience. He offers original studies of four representative historical thinkers whose work enriches the understanding of ostension: Wittgenstein, Merleau-Ponty, Augustine, and Aristotle. And, building on these philosophical and empirical foundations, Engelland offers a meticulous analysis of the philosophical issues raised by ostension. He examines the phenomenological problem of whether embodied intentions are manifest or inferred; the problem of what concept of mind allows ostensive cues to be intersubjectively available; the epistemological problem of how ostensive cues, notoriously ambiguous, can be correctly understood; and the metaphysical problem of the ultimate status of the key terms in his argument: animate movement, language, and mind. Finally, he argues for the centrality of manifestation in philosophy. Taking ostension seriously, he proposes, has far-reaching implications for thinking about language and the practice of philosophy.