bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analysis of the hydrological behaviour of an urbanizing basin
Authors: Furusho C. , Andrieu H. , Chancibault K. 
Published: January 2013

AbstractSuburban areas undergo rapid land‐use changes due to urban growth. Consequently, the mitigation of hydrological impacts is a major issue in the field of flood and water pollution management. Nevertheless, suburban catchments have seldom been studied. This paper presents a method for analyzing the hydrological behaviour of suburban catchments; the particular method is tested on the Chézine catchment, located in a suburban area of Nantes (western France). Chézine provides a typical example of a suburban catchment, yet features the unique behaviour of a response time ranging from 1 to 6 h. It is proposed herein to classify rainfall‐runoff events in homogeneous groups according to their flow coefficient. A group of events is characterized by its mean flow coefficient and by its transfer function, which are considered as the signatures of the hydrological behaviour of these similar events. The transfer function is identified from the available series of rainfall and outflow data. The identified transfer functions serve to estimate the localization of contributing zones over the basin by estimating the basin transfer function from flowpaths. The consistency of these assumptions is then verified by comparing the estimated transfer function with the identified one. The application of this method to the Chézine catchment demonstrates that it is possible to distinguish various types of hydrological behaviour regimes associated with significantly different transfer functions. The joint analysis of the flow coefficient and transfer function of each group confirms that the Chézine catchment reacts like an urban basin with just the urban zones contributing to runoff under dry conditions. Otherwise, the wetter the initial state, the greater the tendency of this basin to react like a natural basin, as reflected by the different transfer function shapes. These results confirm the validity of the proposed method to analyse the various behaviour regimes of suburban catchments. In addition, this method helps define the specifications of hydrological models suited to suburban catchments. Copyright © 2013 John Wiley & Sons, Ltd.
Retracted: CDP/Cut is an osteoblastic coactivator of the vitamin D receptor (VDR)
Authors: Ochiai Eiji , Kitagawa Hirochika , Takada Ichiro , Fujiyama Sally , Sawatsubashi Shun , Kim Mi-sun , Mezaki Yoshihiro , Tsushima Yu , Takagi Ken-ichiro , Azuma Yoshiaki , Takeyama Ken-ichi , Yamaoka Kazuyoshi , Kato Shigeaki , Kamimura Takashi 
Published: January 2013

Abstract
Retraction: The following article from the Journal of Bone and Mineral Research, “CDP/Cut Is an Osteoblastic Coactivator of the Vitamin D Receptor (VDR)” by Eiji Ochiai, Hirochika Kitagawa, Ichiro Takada, Sally Fujiyama, Shun Sawatsubashi, Mi-sun Kim,Yoshihiro Mezaki, Yu Tsushima, Ken-ichiro Takagi, Yoshiaki Azuma, Ken-ichi Takeyama, Kazuyoshi Yamaoka, Shigeaki Kato, Takashi Kamimura, published online on December 11, 2009 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the authors, the journal Editor in Chief, Thomas Clemens, the American Society for Bone and Mineral Research and Wiley Periodicals, Inc. The authors have requested the retraction based on their acknowledgement that several of the figures did not reflect the observations presented.
Disruption of NF-κB1 prevents bone loss caused by mechanical unloading
Authors: Nakamura Hitomi , Aoki Kazuhiro , Masuda Wataru , Alles Neil , Nagano Kenichi , Fukushima Hidefumi , Osawa Kenji , Yasuda Hisataka , Nakamura Ichiro , Mikuni-Takagaki Yuko , Ohya Keiichi , Maki Kenshi , Jimi Eijiro 
Published: January 2013

ABSTRACT

Mechanical unloading, such as in a microgravity environment in space or during bed rest (for patients who require prolonged bed rest), leads to a decrease in bone mass because of the suppression of bone formation and the stimulation of bone resorption. To address the challenges presented by a prolonged stay in space and the forthcoming era of a super-aged society, it will be important to prevent the bone loss caused by prolonged mechanical unloading. Nuclear factor κB (NF-κB) transcription factors are activated by mechanical loading and inflammatory cytokines. Our objective was to elucidate the role of NF-κB pathways in bone loss that are caused by mechanical unloading. Eight-week-old wild-type (WT) and NF-κB1-deficient mice were randomly assigned to a control or mechanically unloaded with tail suspension group. After 2 weeks, a radiographic analysis indicated a decrease in bone mass in the tibias and femurs of the unloaded WT mice but not in the NF-κB1–deficient mice. An NF-κB1 deficiency suppressed the unloading-induced reduction in bone formation by maintaining the proportion and/or potential of osteoprogenitors or immature osteoblasts, and by suppression of bone resorption through the inhibition of intracellular signaling through the receptor activator of NF-κB ligand (RANKL) in osteoclast precursors. Thus, NF-κB1 is involved in two aspects of rapid reduction in bone mass that are induced by disuse osteoporosis in space or bed rest.
Reptiles: A New Model for Brain Evo‐Devo Research
Authors: Nomura Tadashi , Kawaguchi Masahumi , Ono Katsuhiko , Murakami Yasunori 
Published: January 2013

AbstractVertebrate brains exhibit vast amounts of anatomical diversity. In particular, the elaborate and complex nervous system of amniotes is correlated with the size of their behavioral repertoire. However, the evolutionary mechanisms underlying species‐specific brain morphogenesis remain elusive. In this review we introduce reptiles as a new model organism for understanding brain evolution. These animal groups inherited ancestral traits of brain architectures. We will describe several unique aspects of the reptilian nervous system with a special focus on the telencephalon, and discuss the genetic mechanisms underlying reptile‐specific brain morphology. The establishment of experimental evo‐devo approaches to studying reptiles will help to shed light on the origin of the amniote brains. J. Exp. Zool. (Mol. Dev. Evol.) 320B:57–73, 2013. © 2013 Wiley Periodicals, Inc.
Greening organizational behavior: An introduction to the special issue
Authors: Andersson Lynne , Jackson Susan E. , Russell Sally V. 
Published: January 2013

SummaryEach of the six articles in this Special Issue on “Greening Organizational Behavior” offers a perspective that provides unique insight and enriches our understanding of organizational greening. As a set, the articles span all levels of analysis, from a study of individual differences to an investigation of leadership dynamics to the analysis of firms and their institutional environments. Taken together, these articles illustrate the complex nature of organizational greening and highlight the need for research that adopts a systems perspective. The embedded and nested nature of organizational greening behavior requires additional research that investigates the interrelated influences of greening behavior by individual employees, work groups, and organizations. By recognizing and appreciating these multi‐level dynamics, scholars of organizational behavior are poised to improve our understanding of effective organizational greening initiatives and thereby promote advancement toward environmental sustainability. Copyright © 2013 John Wiley & Sons, Ltd.
Mild electrical stimulation with heat stimulation increase heat shock protein 70 in articular chondrocyte
Authors: Hiraoka Nobuyuki , Arai Yuji , Takahashi Kenji A. , Mazda Osam , Kishida Tsunao , Honjo Kuniaki , Tsuchida Shinji , Inoue Hiroaki , Morino Saori , Suico Mary Ann , Kai Hirofumi , Kubo Toshikazu 
Published: January 2013

AbstractThe objective of this study is to investigate the effects of mild electrical stimulation (MES) and heat stress (HS) on heat shock protein 70 (HSP70), that protects chondrocytes and enhances cartilage matrix metabolism, in chondrocyte and articular cartilage. Rabbit articular chondrocytes were treated with MES and/or HS. The safeness was assessed by LDH assay and morphology. HSP70 protein, ubiquitinated proteins and HSP70 mRNA were examined by Western blotting and real‐time PCR. Rat knee joints were treated with MES and/or HS. HSP70 protein, ubiquitinated proteins, HSP70 mRNA and proteoglycan core protein (PG) mRNA in articular cartilage were investigated. In vitro, HS increased HSP70 mRNA and HSP70 protein. MES augmented ubiquitinated protein and HSP70 protein, but not HSP70 mRNA. MES + HS raised HSP70 mRNA and ubiquitinated protein, and significantly increased HSP70 protein. In vivo, HS and MES + HS treatment augmented HSP70 mRNA. HS modestly augmented HSP70 protein. MES + HS significantly increased HSP70 protein and ubiquitinated proteins. PG mRNA was markedly raised by MES + HS. This study demonstrated that MES, in combination with HS, increases HSP70 protein in chondrocytes and articular cartilage, and promotes cartilage matrix metabolism in articular cartilage. MES in combination with HS can be a novel physical therapy for osteoarthritis by inducing HSP70 in articular cartilage. © 2013 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 31: 894–900, 2013
The role of leptin on the organization and expression of cytoskeleton elements in nucleus pulposus cells
Authors: Li Zheng , Shen Jianxiong , Wu William Ka Kei , Yu Xin , Liang Jinqian , Qiu Guixing , Liu Jiaming 
Published: January 2013

AbstractObesity is an important risk factor for intervertebral disc degeneration and leptin is a biomarker of obesity. However, the expression of leptin receptors has not been determined in disc tissue. It is not known whether leptin has a direct effect on the nucleus pulposus (NP) cells. To determine whether the NP tissues and cells express leptin receptors (OBRa and OBRb) and whether leptin affects the organization and the expression of major cytoskeletal elements in NP cells. Messenger RNA (mRNA) and protein levels of OBRa and OBRb were measured by real‐time PCR and Western blot, respectively, in NP tissues and cells. Immunofluorescence and real‐time PCR and Western blot were performed to investigate the effect of leptin on cytoskeleton reorganization and expression. Results show that mRNA and proteins of OBRa and OBRb were expressed in all NP tissues and cells, and that OBRb expression was correlated with patients' body weight. Increased expression of β‐actin and reorganization of F‐actin were evident in leptin‐stimulated NP cells. Leptin also induced vimentin expression but had no effect on β‐tubulin in NP cells. These findings provide novel evidence supporting the possible involvement of leptin in the pathogenesis of intervertebral disc degeneration. © 2013 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 31: 847–857, 2013
Efficacy of voluntary mitigation in reducing harbor seal disturbance
Authors: Hoover‐Miller Anne , Bishop Amanda , Prewitt Jill , Conlon Suzanne , Jezierski Caroline , Armato Peter 
Published: January 2013

AbstractMarine and coastal tourism has rapidly expanded worldwide in the past 2 decades, often occurring in once secluded habitats. In Alaska, tourism near tidewater glaciers has attracted millions of visitors and increased the presence of ships, tour vessels, and coastal development. Although sustainable tourism, resulting from balanced effects on wildlife and client satisfaction, is a goal of most tourism operators, it is not always achieved. Voluntary compliance with viewing guidelines and codes of conduct have been encouraged, but few assessments have the longitudinal scope to evaluate long‐term changes in impacts on wildlife and the ability of vessel operators and kayak guides to sustain lower impact operating practices over time. This study assessed vessel and kayak visitation and resulting impacts on harbor seals in the Kenai Fjords National Park, southcentral Alaska. We obtained observations from 2002 to 2011, using remotely controlled video cameras located near Aialik and Pedersen Glaciers in the Kenai Fjords National Park. Overall, disturbance was associated with 5.1% of vessel sightings, 28% of vessel interactions (vessel observed within approx. 300 m of seals), 11.5% of kayak sightings, and 61% of kayak interactions. Results demonstrated that voluntary changes in operations significantly reduced vessel and kayak disturbance of seals by 60–80%. Even with prior establishment of operating guidelines, tour vessel captains were able to further reduce their effect on wildlife with more careful operations. Rapid growth of guided kayak excursions that occurred during this study caused greater disturbance to seals than motorized vessels but guide trainings helped reduce disturbances. Diminished impacts of motor vessels and kayakers persisted across years although effects of kayaks were less consistent than motor vessels, which reflected greater variability in inter‐annual spatial use patterns by kayakers. Long‐term monitoring, including assessments of wildlife responses to vessel and kayak operations, combined with 2‐way communication with vessel operators and guides, enhanced the effectiveness of mitigation and facilitated adaptive adjustments to mitigation protocols over time. © 2013 The Wildlife Society.
Marten space use and habitat selection in managed coniferous boreal forests of eastern Canada
Authors: Cheveau Marianne , Imbeau Louis , Drapeau Pierre , Belanger Louis 
Published: January 2013

AbstractEffects of habitat loss and fragmentation on the behavior of individual organisms may have direct consequences on population viability in altered forest ecosystems. The American marten (Martes americana) is a forest specialist considered as one of the most sensitive species to human‐induced disturbances. As some studies have shown that martens cannot tolerate >30–40% clear‐cuts within their home range, we investigated marten space use (home range size and overlap) and habitat selection in landscapes fragmented by 2 different patterns of timber harvesting in the black spruce boreal forest: dispersed‐cut landscapes (10–80 ha cut‐blocks) and clustered‐cut landscapes (50–200 ha cut‐blocks). We installed radio‐collars on female martens and determined 20 winter home ranges (100% minimum convex polygons and 60–90% kernels) in dispersed‐cut (n = 8) and clustered‐cut (n = 12) landscapes. Home range size was not related to the proportion of clear‐cuts (i.e., habitat loss), but rather to the proportion of mixedwood stands 70–120 years old. However, female body condition was correlated to habitat condition inside their home ranges (i.e., amount of residual forest and recent clear‐cuts). At the home range scale, we determined that mixedwood forests were also among the most used forest stands and the least used were recent clear‐cuts and forested bogs, using resource selection functions. At the landscape scale, home ranges included more mixedwood forests than random polygons and marten high activity zones were composed of more residual forest and less human‐induced disturbances (clear‐cuts, edges, and roads). These results suggest that mixedwood forests, which occupy approximately 10% of the study area, play a critical role for martens in this conifer‐dominated boreal landscape. We recommend permanent retention or special management considerations for these isolated stands, as harvesting mixedwood often leads to forest composition conversion that would reduce the availability of this highly used habitat. © The Wildlife Society, 2013
Photonic time‐stretch digitizer and its extension to real‐time spectroscopy and imaging
Authors: Fard Ali M. , Gupta Shalabh , Jalali Bahram 
Published: January 2013

AbstractReal‐time wideband digitizers are the key building block in many systems including oscilloscopes, signal intelligence, electronic warfare, and medical diagnostics systems. Continually extending the bandwidth of digitizers has hence become a central challenge in electronics. Fortunately, it has been shown that photonic pre‐processing of wideband signals can boost the performance of electronic digitizers. In this article, the underlying principle of the time‐stretch analog‐to‐digital converter (TSADC) that addresses the demands on resolution, bandwidth, and spectral efficiency is reviewed. In the TSADC, amplified dispersive Fourier transform is used to slow down the analog signal in time and hence to compress its bandwidth. Simultaneous signal amplification during the time‐stretch process compensates for parasitic losses leading to high signal‐to‐noise ratio. This powerful concept transforms the analog signal's time scale such that it matches the slower time scale of the digitizer. A summary of time‐stretch technology's extension to high‐throughput single‐shot spectroscopy, a technique that led to the discovery of optical rouge waves, is also presented. Moreover, its application in high‐throughput imaging, which has recently led to identification of rogue cancer cells in blood with record sensitivity, is discussed.
Tm:Fiber laser ablation with real‐time temperature monitoring for minimizing collateral thermal damage: ex vivo dosimetry for ovine brain
Authors: Tunc Burcu , Gulsoy Murat 
Published: January 2013

AbstractBackground and ObjectiveThe thermal damage of the surrounding tissue can be an unwanted result of continuous‐wave laser irradiations. In order to propose an effective alternative to conventional surgical techniques, photothermal damage must be taken under control by a detailed dose study. Real‐time temperature monitoring can be also an effective way to get rid of these negative effects. The aim of the present study is to investigate the potential of a new laser‐thermoprobe, which consists of a continuous‐wave 1,940‐nm Tm:fiber laser and a thermocouple measurement system for brain surgery in an ex vivo study.Study Design/Materials and MethodsA laser‐thermoprobe was designed for using the near‐by tissue temperature as a real‐time reference for the applicator. Fresh lamb brain tissues were used for experiments. 320 laser shots were performed on both cortical and subcortical tissue.ResultsThe relationship between laser parameters, temperature changes, and ablation (removal of tissue) efficiency was determined. The correlation between rate of temperature change and ablation efficiency was calculated.ConclusionLaser‐thermoprobe leads us to understand the basic laser–tissue interaction mechanism in a very cheap and easy way, without making a change in the experimental design. It was also shown that the ablation and coagulation (thermally irreversible damage) diameters could be predicted, and carbonization can be avoided by temperature monitoring. Lasers Surg. Med. 45: 48–56, 2013. © 2013 Wiley Periodicals, Inc.
Insights in the Architecture of Silicon‐Based Plasma Polymers Using Partial Network Ethanolysis Combined with Electrospray Tandem Mass Spectrometry
Authors: Fouquet Thierry , Petersen Julien , Ziarelli Fabio , Bour Jérôme , Toniazzo Valérie , Ruch David , Charles Laurence 
Published: January 2013

AbstractThin films obtained upon plasma polymerization of D4 and HMDSO precursors at atmospheric pressure are submitted to controlled ethanolysis to produce oligomers amenable to electrospray mass spectrometry. When using high resolution mass spectrometry to assess their elemental composition and tandem mass spectrometry to characterize their end‐groups, a whole set of ethanolysis products is identified, from which the network connectivity in the original film can be reconstructed. Ethanolysis products of ppD4 and ppHMDSO exhibit the same structural features composed of linear and cross‐linked PDMS moieties, the extent of cross‐linking reflecting the inorganic character of the film. Oligomers originally embedded in the solid network and released as intact species upon its dissolution are also observed. magnified image
Vivaldi: Visualization and validation of biomacromolecular NMR structures from the PDB
Authors: Hendrickx Pieter M. S. , Gutmanas Aleksandras , Kleywegt Gerard J. 
Published: January 2013

AbstractWe describe Vivaldi (VIsualization and VALidation DIsplay; http://pdbe.org/vivaldi), a web‐based service for the analysis, visualization, and validation of NMR structures in the Protein Data Bank (PDB). Vivaldi provides access to model coordinates and several types of experimental NMR data using interactive visualization tools, augmented with structural annotations and model‐validation information. The service presents information about the modeled NMR ensemble, validation of experimental chemical shifts, residual dipolar couplings, distance and dihedral angle constraints, as well as validation scores based on empirical knowledge and databases. Vivaldi was designed for both expert NMR spectroscopists and casual non‐expert users who wish to obtain a better grasp of the information content and quality of NMR structures in the public archive. © Proteins 2013. © 2012 Wiley Periodicals, Inc.
Deriving how far structural information is transmitted through parallel homodimeric coiled‐coils: A correlation analysis of helical staggers
Authors: Brown Jerry H. 
Published: January 2013

AbstractHow local conformation is affected by local sequence is fairly well understood for alpha‐helical coiled‐coils, but less is known about how local conformation is influenced by distant features. Here, I describe an approach to detect such an effect, based on computing correlation coefficients of local out‐of‐register alignments, or so‐called “staggers” between the helices, as a function of the axial distance between the staggers. This approach requires parallel homodimers, in which each stagger can occur with two “signs,” where either one helix or the other is shifted towards the N terminus. The signs of such staggers separated by up to 12 residues are strongly correlated, indicating that the conformations of the ends of coiled‐coils are commonly influenced by attached structures. Thus, the structures of coiled‐coil residues aberrantly attached to alternative proteins, such as those resulting from leukemogenic chromosomal rearrangements, may be distinguishable from those in normal tissues, and in turn serve as targets of selective drug design. The signs of helical staggers separated by between 13 and 30 residues are moderately yet significantly correlated, indicating that some of the coiled‐coils transmit this conformational feature axially for at least 45 Å. A positive, albeit noisy, correlation also exists among tropomyosin coiled‐coils for signed staggers separated by the 40‐residue actin repeat distance, consistent with the semi‐flexible tropomyosin filament binding F‐actin and regulating skeletal muscle contraction in a partially cooperative manner. Communication of the signs of axial staggers is explained in part by minimization of main‐chain hydrogen bond deformations. © Proteins 2013. © 2012 Wiley Periodicals, Inc.