bluuebunny/crossref_metadata_2025_split huggingface dataset:
Deep reinforcement learning enhances artistic creativity: The case study of program art students integrating computer deep learning
Authors: Zhao Feng 
Published: June 2024

Abstract
During the artistic journey, creators frequently encounter challenges stemming from pressure, resource constraints, and waning inspiration, all of which can impede their creative flow. Addressing these obstacles requires a multifaceted strategy aimed at nurturing creativity throughout the artistic process. Procedural art generation emerges as a viable solution to invigorate artistic creativity. In this study, the deep Q-network (DQN) was constructed to solve the shortage of artistic creativity through its automatic decision-making ability. The model was trained with different types of artistic styles (abstract and minimalism) in WikiArt dataset. The model generates various artistic elements of different styles, forms, or thinking according to the input parameters or constraints, and selects specific colors, textures, or shapes to help the artist maintain focus in the creation process and expand the creativity in the creation process. In order to achieve this goal, in the process of performing the procedural art generation task with DQN, the experiment collected the generation speed, interpretability, and creativity evaluation feedback of each style of art. The feedback results show that the scores of color field painting and minimalism were 83.2, 93.5, 86.3 and 86.6, 91.5, 82.1 respectively. The research shows that employing dynamic mass spectrometry networks enables the automation of the art creation process. This innovative approach facilitates the exploration of diverse creative ideas tailored to various artistic tasks, thereby fostering advancements in art creation and nurturing creativity.
New findings on the karyotype and distribution of two Rhipidomys Tschudi, 1845 species (Rodentia: Sigmodontinae) from Upper Purus River
Authors: Lanes Rayque de Oliveira , Pires Carolina , Teixeira Bernardo R. , Bonvicino Cibele R. 
Published: July 2024

Abstract

Rhipidomys is a Sigmodontinae genus with a great diversity in western Amazonia, including Rhipidomys gardneri and Rhipidomys leucodactylus. These species shared the same diploid number of 44, however, two fundamental numbers were attributed to R. leucodactylus and one to R. gardneri. A new karyotype for R. leucodactylus is described, with a diploid and fundamental number shared by other Rhipidomys species. Data confirmed three karyotypes for R. leucodactylus, only one for R. gardneri, the presence of R. leucodactylus in the Brazilian state of Acre and extend the distribution of R. gardneri to Manoel Urbano, in Acre, showing both species occurring in the high Purus River basin.
A CNN-CBAM-BIGRU model for protein function prediction
Authors: Sharma Lavkush , Deepak Akshay , Ranjan Ashish , Krishnasamy Gopalakrishnan 
Published: June 2024

Abstract
Understanding a protein’s function based solely on its amino acid sequence is a crucial but intricate task in bioinformatics. Traditionally, this challenge has proven difficult. However, recent years have witnessed the rise of deep learning as a powerful tool, achieving significant success in protein function prediction. Their strength lies in their ability to automatically learn informative features from protein sequences, which can then be used to predict the protein’s function. This study builds upon these advancements by proposing a novel model: CNN-CBAM+BiGRU. It incorporates a Convolutional Block Attention Module (CBAM) alongside BiGRUs. CBAM acts as a spotlight, guiding the CNN to focus on the most informative parts of the protein data, leading to more accurate feature extraction. BiGRUs, a type of Recurrent Neural Network (RNN), excel at capturing long-range dependencies within the protein sequence, which are essential for accurate function prediction. The proposed model integrates the strengths of both CNN-CBAM and BiGRU. This study’s findings, validated through experimentation, showcase the effectiveness of this combined approach. For the human dataset, the suggested method outperforms the CNN-BIGRU+ATT model by +1.0 % for cellular components, +1.1 % for molecular functions, and +0.5 % for biological processes. For the yeast dataset, the suggested method outperforms the CNN-BIGRU+ATT model by +2.4 % for the cellular component, +1.2 % for molecular functions, and +0.6 % for biological processes.
Real-world cross-comparison of metabolic outcomes with different sodium-glucose co-transporter 2 inhibitors agents in adults with type 2 diabetes: results from the Association of British Clinical Diabetologists audit programme
Authors: Crabtree Tom 
Published: June 2024

Sodium-glucose co-transporter-2 inhibitors (SGLT2i) have demonstrated significant efficacy in improving cardiorenal and metabolic outcomes, However, whether there are differences between agents remain unclear. We therefore assessed changes in haemoglobin A1c (HbA1c), weight, body mass index (BMI) and systolic blood pressure (SBP) across the class; and between agents.
Methods: Individuals using empagliflozin (E), canagliflozin (C) or dapagliflozin (D) in the ABCD audits were included provided that data were available for the outcomes of interest. Multivariate linear regression analysis was used to assess adjusted change in HbA1c, weight, BMI and SBP and to compare outcomes between drugs. Analyses were performed in Stata 17.
Results: 21,263 individuals (E=11,231; C=2,257; D=7,775) with mean±SD age 60.0±10.4years, HbA1c 75.3±17.2 mmol/mol, BMI 33.9±7.1kg/m2 and 61.2% female were included. Over median follow-up of 1.7 years, HbA1c reduced by 10.0 mmol/mol (95% CI 9.8-10.2; p<0.001); weight reduced by 3.2 kg (95% CI 2.2-4.1; p<0.001); BMI reduced by 1.1 kg/m2 (95% CI 0.8-1.5; p<0.001) and SBP reduced by 0.9 mmHg (95% CI 0.7-1.1; p<0.001). Empagliflozin was associated with larger HbA1c reduction than dapagliflozin and canagliflozin (-10.6 mmol/mol [E] vs -9.8 mmol/mol [C] vs -9.1 mmol/mol [D]; p<0.001 for both). Canagliflozin was associated with statistically larger SBP reductions compared to dapagliflozin (-1.6 mmHg [C] vs 0.6 mmHg [D]). No differences were noted in weight and BMI change between drugs. Discontinuation of SGLT2i therapy was rare, only occurring in 0.35% (75/21,338). Our cohort has individuals with higher baseline weight and HbA1c compared to published trial data and may be more generalisable to a UK population.
Conclusion: SGLT2i are very well tolerated and are associated with improvements in multiple metabolic and clinical parameters in UK real-world practice. Relatively small differences were observed between agents for HbA1c and SBP reduction, but not for weight reduction. Further work should focus on establishing the association between individual SGLT2i agents and hard cardiorenal end points in the real world.
The “Tumbling Gallstone Sign” of Obstructive Gallstone Ileus
Authors: Theodorou Daphne J. , Theodorou Stavroula J. , Gkogkos Vasilios , Ziogas Dimosthenis 
Published: June 2024

The "tumbling gallstone sign" is a diagnostic imaging finding described on radiologic examinations of the abdomen, in patients with cholelithiasis associated with intermittent episodes of gallstone obstructive ileus. Best seen on serial radiographs or CT studies of the abdomen, this sign indicates a sudden change in position of the gallstone(s) within the intestinal lumen from the upper segments of the bowel to the lower segments of the bowel, causing transient mechanical bowel obstruction. The tumbling gallstone sign has been likened to that of the classic childrens' tumbling tower balancing game. On repeat CT scans, the dislodged gallstone(s) may be seen proceeding distally and impact in the ileum at a level lower than that seen on the previous CT scans, analogous to the tumbling gallstone sign.
Humanización, sensibilidad ética y toma de decisión del personal de salud en UCI
Authors: Sánchez–Alfaro Luis Alberto , Carmona González Yolima de Jesús , Corredor Silva Liced Yurany , Ramírez Ortíz Jeniffer Carolina , Boscán Barrera Rita Del Carmen 
Published: July 2024

Objetivo: interpretar la relación entre humanización y sensibilidad ética con la toma de decisiones del personal de la salud que labora en unidades de cuidado intensivo (UCI) en Bogotá y Cartagena.
Materiales y método: estudio cualitativo de tipo comprensivo. Se emplearon tres herramientas de recolección de información: entrevista semiestructurada en línea, análisis de caso y la diada observación participante-diario de campo. Inicialmente, se realizó codificación, categorización, disposición y agrupamiento de datos (análisis categorial deductivo); luego, análisis del discurso y hermenéutica de ideas, identificando dos categorías emergentes (análisis categorial inductivo): Rostros en la UCI y Cultivo del profesionalismo.
Resultados: Rostros en la UCI evidencia que, como territorio, en estas unidades interactúan subjetividades, roles y expectativas encarnadas por quienes las habitan. Cultivo del profesionalismo, como rasgo de carácter, se expresa mediante la práctica de virtudes y se perfecciona a partir de experiencias profesionales y personales.
Conclusiones: la relación entre humanización y sensibilidad ética con la toma de decisiones en UCI está mediada por varios factores entre el personal de salud que trabaja en estas unidades, como el rol, la jerarquía, el sexo, el cansancio y la angustia moral. El cultivo del profesionalismo ocurre a partir de las experiencias personales y profesionales en UCI que permiten objetivar la experiencia de atención y generan alguna reflexión que impulsa el cultivo de virtudes como la compasión. La humanización, la sensibilidad ética y la toma de decisiones se expresan de manera desigual entre los profesionales de la salud, lo cual se explica principalmente por la jerarquía dentro del equipo de UCI, la proximidad con el paciente y los vínculos establecidos.
Sensitivity Analysis and GIS Tools for Groundwater Vulnerability Assessment. (Application in the Middle Chellif Plain, Algeria)
Authors: Nadjai Saci , Khammar Hichem , Boulebaiz Mahreez , Nabed Abdelkader Nadir , Benaabidate Lahcen 
Published: July 2024

Contamination due to rapid urban development, industrialization, and agricultural sources is increasingly threatening the groundwater resources of the plioquaternary phreatic aquifer of the Middle Western Cheliff. An intrinsic vulnerability assessment was carried out based on the DRASTIC method on parameters involved in the vertical transfer of pollution from the soil surface. The vulnerability maps obtained showed a high extension of areas of medium vulnerability (54%). On the other hand, areas of low vulnerability occupied about 36%. The high and very high vulnerability was mainly related to low water depth values (8% and 2%, respectively). The results of a sensitivity analysis using the two tests—the single parameter sensitivity analysis and the map removal sensitivity analysis—show that every parameter is, without fail, required for the computation of the vulnerability index. The validation of the vulnerability map produced by the DRASTIC method confirmed the evolution of this sensitivity which decreases towards the S.W. of the plain with nitrate concentrations between 30 and 120 mg/L. Planners can use the produced risk maps as tools to make a preliminary choice of priority locations for various forms of environmental sustainability.
'Laban, Laban'
Authors: Hourani Afnan 
Published: June 2024

I was born in Baghdad of a Persian father and a half-Turkish mother. My mother's other half was from Aleppo and later I married a Lebanese. This mixture enabled me to live in and travel to yoghurt eating countries most of my life and has therefore enabled me to collect traditional yoghurt recipes. The collection has now grown to the point of constituting a book, which I hope will find a publisher.
In the course of my research I asked friends, relatives and their cooks for recipes and this led to many discussions about yoghurt and its different uses in Turkey, Iran and the Eastern Arab world. It is not common in North Africa, to my chagrin as I spent ten years of my life in Tunisia. I learned that the same traditional method of making yoghurt is used all over and that it is an essential part of the culture. So much so that the early Lebanese emigrants dipped bits of cloth in yoghurt and dried them in the open air. The bits of cloth were taken to their new homes in America, Brazil, Australia or wherever, and reconstituted into yoghurt to be used as starters.
Efeitos reprodutivos da exposição oral crônica ao glifosato em condições ambientalmente relevantes: um estudo experimental
Authors: Simões Jamile Silveira Tomiazzi , Bastianini Mariana Esperendi , Silva Jaqueline Nascimento , Rossi Renata Calciolari , Favareto Ana Paula Alves 
Published: June 2024

O herbicida glifosato está entre os mais utilizados no mundo. Assim, tornou-se crescente a preocupação com seus possíveis efeitos adversos sobre a saúde. Este estudo teve como objetivo avaliar os efeitos reprodutivos do consumo crônico de ração contaminada com o herbicida glifosato em ratos. Ratos receberam ração nebulizada com solução de glifosato em diferentes concentrações: 0 (grupo controle - GC), 20,69 (grupo de baixa concentração - GBC), 34,63 (grupo de média concentração - GMC) ou 51,66 ppm por dia (grupo de alta concentração GAC), durante 180 dias. A qualidade dos espermatozoides foi prejudicada pelo glifosato. A porcentagem de espermatozoides com movimentação progressiva e não progressiva e contagem de espermatozoides no testículo foram reduzidos nos dois grupos de maior concentração de exposição (GMC e GAC). Houve aumento de alterações de cabeça com curvatura em forma de alfinete e anormal e cauda isolada e enrolada nos três grupos expostos com redução significativa no número de espermatozoides normais. A integridade de membrana plasmática do espermatozoide não foi afetada pelo herbicida. A exposição crônica oral ao herbicida glifosato em diferentes concentrações causou alterações na morfologia de espermatozoides de ratos adultos. Tais achados são cruciais, pois sugerem que a exposição prolongada ao glifosato pode ter implicações prejudiciais na fertilidade masculina, ressaltando a necessidade de constantes revisões nas práticas de uso do herbicida e na avaliação dos seus riscos à saúde.
Effect of the mindfulness-based program on stress, anxiety and physiological changes among nurse aid students attending the 9 months course of nurse aid training in Myanmar
Authors: Aye Aung Lin , Win Hla Hla , Thandar Mya , Oo Soe Min 
Published: June 2024

Background: Suffering under stress and anxiety was a big challenge for the majority of nurse aid students and it was requisite to pass the 9 months training without attrition to become a qualified nurse aid.
Methods: From 1st week of February to 4th week of May, 2023, 104 nurse aid training students (51 participants in intervention group and 53 participants in control group) from 7 tertiary hospitals in the Yangon Region were conducted by a quasi-experimental study. Data collection was done by asking questionnaire for stress and anxiety, and by collecting blood samples to test serum cortisol level. Data was analysed by using SPSS 23 and independent t-test, one-way repeated measures ANOVA and multiple linear regression with propensity score adjustment were applied.
Results: The mean changes (before- after- followed up) in the Perceived Stress Scale (PSS) and in the Generalized Disorder Scale (GAD) were significantly different between the intervention and control groups displaying a difference in difference mean change of 4.13 (2.41, 5.86) at p<0.001, 3.02 (95%CI: 1.05, 4.99) at p=0.003 and that of 2.45 (95% CI: 1.24, 3.66), p<0.001, 1.49 (95%CI: 0.16, 2.83) at p=029 respectively. Moreover, there was a significant decrease (before-after 8 week intervention) in the serum cortisol level between two groups showing a difference in difference mean change of 39.66 (95% CI: 4.97, 74.34), p=0.026.
Conclusions: This study might observe as supportive evidence of the mindfulness-based program to manage stress and anxiety among nurse aid students.
EVOLUÇÃO DA TECNOLOGIA NO CONTEXTO EDUCACIONAL: ETE PROFESSOR URBANO GOMES DE SÁ – SALGUEIRO-PE
Authors: Barros e silva Vanessa ohara 
Published: June 2024

Resumo
Este artigo buscou explorar a inserção das tecnologias na educação através de análise documental do Projeto Político Pedagógico da Escola Técnica Professor Urbano Gomes de Sá, situada na zona urbana de Salgueiro, Pernambuco, onde foi realizado um breve comparativo sobre o que foi proposto de uso de tecnologia em sala de aula no ano de 2005 e 2023. O artigo também se apoiou em dois estudos de caso que foram realizados no estado do Ceará e de Alagoas, ambas sobre a rede pública de ensino, e que o Projeto Político Pedagógico também previa o uso de tecnologias em sala de aula. Como resultado, foi identificado o crescente uso de computadores em laboratórios de informática, além de inserção de outros recursos tais como impressora 3D e kits de robótica, ampliando o ensino-aprendizagem dos alunos.

Palavras-chave: tecnologia; contexto educacional; Urbano Gomes de Sá.
AS EXPERIÊNCIAS E POSSIBILIDADES FORMATIVAS NA REALIZAÇÃO DO ESTÁGIO CURRICULAR SUPERVISIONADO REMOTO E PRESENCIAL
Authors: BIKEL ROQUE LUIZ , RODRIGUES MACHADO PIETRO NICOLAS , Cerignoni Benites Larissa 
Published: July 2024

Este relato tem como objetivo relatar as experiências advindas do Estágio Curricular Supervisionado (ECS) no ensino remoto emergencial (ERE) e presencial. Trata-se de um relato de abordagem qualitativa que apresenta em seu desenvolvimento as percepções de um estagiário sobre esses dois momentos, buscando evidenciar dificuldades e possibilidades sobre sua formação docente. Dessa forma, se destaca as experiências no ERE que oportunizaram a compreensão da dinâmica das práticas pedagógicas na medida em que nos deparamos com situações que envolvem o ensino e a aprendizagem, tais como: análise de documentos, criação de videoaula e colcha de retalhos. Já no estágio presencial emergiram particularidades sobre a realidade da escola e sua complexidade, a relação teoria e prática, postura profissional e fazeres docentes. Assim, houve a oportunidade de ir percebendo a própria construção para docência, além de realizar reflexões oportunizadas pelos professores e o contato com os alunos. Por fim, em ambos ECS houve desafios, (re)construções, conquistas que permitiram olhar para as exigências da profissão, superando impressões prévias, destacando aprendizados e fortificando a escolha profissional.
AVANÇOS E DIFICULDADES NA RECEPÇÃO DA LUMEN GENTIUM
Authors: Routhier Gilles 
Published: June 2024

Soixante ans après la fin du concile, la réception de Vatican II, processus long et complexe, se poursuit encore. Résumée dans la notion de « peuple de Dieu » adoptée avec enthousiasme par l’ensemble des fidèles puisqu’elle marquait la fin de la marginalisation des laïcs, l’ecclésiologie conciliaire a dû être approfondie. Si l’Assemblée extraordinaire du Synode des évêques de 1985 semble marquer un recul, elle a obligé un approfondissement exigeant, approfondissement qui a conduit à une résurgence au cours du pontificat de François qui reprend l’enseignement du concile sur le peuple de Dieu, la collégialité, la participation active de tous à la mission et le sensus fidei qui appartient à tous les fidèles.
Diffusive Leakage of scCO2 in Shaly Caprocks: Effect of Geochemical Reactivity and Anisotropy
Authors: Cruz Felipe , Dang Son , Curtis Mark , Rai Chandra 
Published: July 2024

Summary
Supercritical carbon dioxide (scCO2) trapping mechanisms within carbon geostorage (CGS) primarily hinge on the upper caprock system, with shales being favored for their fine-grained nature and geological abundance. Experimental assessments of CO2 reactivity in brine-saturated shales reveal microstructural changes, raising concerns about long-term CO2 leakage risks. Existing models of scCO2 transport through caprocks lack consideration for shale anisotropy. This study addresses these gaps by investigating the diffusive properties and propagation of geochemical reactivity in shaly caprocks, accounting for anisotropy. Horizontal and vertical core samples from three shale formations with varying petrophysical characteristics underwent mineralogical, total organic carbon (TOC), porosity, and velocity measurements. scCO2 treatment for up to 3 weeks at 150°F and 3,000 psi was conducted. The propagation of geochemical reactivity was monitored by multiple surface X-ray fluorescence (XRF) measurements and fine polishing. A nuclear magnetic resonance (NMR)-based H2O-D2O fluid exchange protocol was used to quantify effective diffusivities and tortuosities parallel and perpendicular to bedding. Results indicate preferential surface reactivity toward carbonate minerals; however, the apparent reaction diffusivity of the shaly caprock is notably slow (~10−15 m2/s). This aligns with previous experimental and reactive transport modeling studies, emphasizing long timescales for carbonate dissolution reactions to influence shale caprock properties. Shale-effective diffusivities display anisotropy increasing with clay content, where diffusivities parallel to bedding exceed those perpendicular by at least three times. Faster horizontal diffusion in shaly confining zones should be considered when estimating diffusive leakage along faults penetrating these zones, a significant risk in CGS. Post-scCO2 treatment, diffusivity changes vary among samples, increasing within the same order of magnitude in the clay-rich sample. Nonsteady-state modeling of scCO2 diffusion suggests limited caprock penetration over 100 years, with a minimal increase from 5 m to 7 m post-scCO2 treatment for the clay-rich sample. This study extends existing literature observations on the slow molecular diffusion of scCO2 within shaly caprocks, integrating the roles of geochemical reactions and shale anisotropy under the examined conditions.