bluuebunny/crossref_metadata_2025_split huggingface dataset:
Troilos and Achilles: A Monumental Statue Group from Aphrodisias
Authors: Smith R. R. R. , Hallett C. H. 
Published: August 2015

AbstractA remarkable blue-grey marble horse with a white marble rider, found in the Basilica at Aphrodisias, has been a focus of recent research. The article describes the archaeology and history of the monument — how it can be reconstructed, with its base and in its precise setting in the Basilica. The group was a daring composition that had already fallen and been restored once in antiquity. What emerges is firstly a new full-size hellenistic-style statue group whose subject can be identified as Troilos and Achilles, and secondly a striking example of the long second lives of classical statues in Late Antiquity. The horse was a great public monument of the early imperial period that was moved to the Basilica probably in the mid-fourth centurya.d., where it has a well-documented context. The subject of the group can be identified both from epigraphy and from its iconographic antecedents, and its version of the subject can be related to a particular strand in the rich later literary representations of the story.1
Application of the multifactor dimensionality reduction method in evaluation of the roles of multiple genes/enzymes in multidrug-resistant acquisition in Pseudomonas aeruginosa strains
Authors: YAO Z. , PENG Y. , BI J. , XIE C. , CHEN X. , LI Y. , YE X. , ZHOU J. 
Published: August 2015

SUMMARYMultidrug-resistant Pseudomonas aeruginosa (MDRPA) infections are major threats to healthcare-associated infection control and the intrinsic molecular mechanisms of MDRPA are also unclear. We examined 348 isolates of P. aeruginosa, including 188 MDRPA and 160 non-MDRPA, obtained from five tertiary-care hospitals in Guangzhou, China. Significant correlations were found between gene/enzyme carriage and increased rates of antimicrobial resistance (P < 0·01). gyrA mutation, OprD loss and metallo-β-lactamase (MBL) presence were identified as crucial molecular risk factors for MDRPA acquisition by a combination of univariate logistic regression and a multifactor dimensionality reduction approach. The MDRPA rate was also elevated with the increase in positive numbers of those three determinants (P < 0·001). Thus, gyrA mutation, OprD loss and MBL presence may serve as predictors for early screening of MDRPA infections in clinical settings.
Impact of the 13-valent pneumococcal conjugate vaccine on the incidence of pneumococcal meningitis in children
Authors: CHAPOUTOT A. G. , DESSEIN R. , GUILLUY O. , LAGRÉE M. , WALLET F. , VARON E. , MARTINOT A. , DUBOS F. 
Published: August 2015

SUMMARYThe impact of the 13-valent pneumococcal conjugate vaccine (PCV13) on the incidence of pneumococcal meningitis (PM) in children is unknown. To determine this impact, a descriptive multicentre retrospective cohort study was conducted from 2008 to 2013 in northern France. All laboratory-confirmed PM in children aged <18 years in all hospitals of the area with paediatric units were included. Two independent databases were used for exhaustive identification of cases: medical plus laboratory records at each hospital and discharge codes. The corrected incidence of PM was determined by a capture–recapture analysis using these two databases. Sixty-two cases were found over the 6-year period. A decrease of the PM corrected incidence was observed in the global population (P = 0·07), significant only for children aged <2 years, from 11·9/100 000 in 2008 in 1·9/100 000 in 2013 [6·4 fold-decrease, 95% confidence interval (CI) 1·4–41, P = 0·01] between years 2008 and 2013. When comparing the pre- and post-PCV13 periods, this decrease was still statistically significant for children aged <2 years [7·32/100 000 (95% CI 4·39–10·25) to 2·78/100 000 (95% CI 0·96–4·60), P = 0·01]. Only three (5%) cases of PM caused by vaccine serotypes could have been prevented. After the introduction of the PCV13 vaccine, a decrease in the incidence of PM cases in children in northern France was observed.
Cultures of nuclear resistance in 1980s Liverpool
Authors: HOGG JONATHAN 
Published: August 2015

ABSTRACT:Focusing on Liverpool in the early 1980s, this article argues that localized approaches to Cold War cities can help us understand the impact of national nuclear policy on cultures of local government and everyday life. After an articulation of cultural politics in the early 1980s, this article suggests that nuclear cultures that existed in Liverpool were shaped by ideas and assumptions discursively reinforced at both a national and local level.
Modernising historical Slovene words
Authors: SCHERRER YVES , ERJAVEC TOMAŽ 
Published: August 2015

AbstractWe propose a language-independent word normalisation method and exemplify it on modernising historical Slovene words. Our method relies on character-level statistical machine translation (CSMT) and uses only shallow knowledge. We present relevant data on historical Slovene, consisting of two (partially) manually annotated corpora and the lexicons derived from these corpora, containing historical word–modern word pairs. The two lexicons are disjoint, with one serving as the training set containing 40,000 entries, and the other as a test set with 20,000 entries. The data spans the years 1750–1900, and the lexicons are split into fifty-year slices, with all the experiments carried out separately on the three time periods. We perform two sets of experiments. In the first one – a supervised setting – we build a CSMT system using the lexicon of word pairs as training data. In the second one – an unsupervised setting – we simulate a scenario in which word pairs are not available. We propose a two-step method where we first extract a noisy list of word pairs by matching historical words with cognate modern words, and then train a CSMT system on these pairs. In both sets of experiments, we also optionally make use of a lexicon of modern words to filter the modernisation hypotheses. While we show that both methods produce significantly better results than the baselines, their accuracy and which method works best strongly correlates with the age of the texts, meaning that the choice of the best method will depend on the properties of the historical language which is to be modernised. As an extrinsic evaluation, we also compare the quality of part-of-speech tagging and lemmatisation directly on historical text and on its modernised words. We show that, depending on the age of the text, annotation on modernised words also produces significantly better results than annotation on the original text.
Reliable Change on Neuropsychological Tests in the Uniform Data Set
Authors: Gavett Brandon E. , Ashendorf Lee , Gurnani Ashita S. 
Published: August 2015

AbstractLongitudinal normative data obtained from a robust elderly sample (i.e., believed to be free from neurodegenerative disease) are sparse. The purpose of the present study was to develop reliable change indices (RCIs) that can assist with interpretation of test score changes relative to a healthy sample of older adults (ages 50+). Participants were 4217 individuals who completed at least three annual evaluations at one of 34 past and present Alzheimer’s Disease Centers throughout the United States. All participants were diagnosed as cognitively normal at every study visit, which ranged from three to nine approximately annual evaluations. One-year RCIs were calculated for 11 neuropsychological variables in the Uniform Data Set by regressing follow-up test scores onto baseline test scores, age, education, visit number, post-baseline assessment interval, race, and sex in a linear mixed effects regression framework. In addition, the cumulative frequency distributions of raw score changes were examined to describe the base rates of test score changes. Baseline test score, age, education, and race were robust predictors of follow-up test scores across most tests. The effects of maturation (aging) were more pronounced on tests related to attention and executive functioning, whereas practice effects were more pronounced on tests of episodic and semantic memory. Interpretation of longitudinal changes on 11 cognitive test variables can be facilitated through the use of reliable change intervals and base rates of score changes in this robust sample of older adults. A Web-based calculator is provided to assist neuropsychologists with interpretation of longitudinal change. (JINS, 2015, 21, 558–567)
Connecting Self-Awareness and Error-Awareness in Patients with Traumatic Brain Injury
Authors: Dockree Paul M. , Tarleton Yvonne M. , Carton Simone , FitzGerald Mary C.C. 
Published: August 2015

AbstractImpaired self-awareness after traumatic brain injury (TBI) is often seen in stark contrast to the observations of significant-others, who are acutely aware of the difficulties experienced by patients. Our objective was to investigate the relationship between metacognitive knowledge in daily life and emergent awareness of errors during laboratory tasks, since the breakdown of error detection mechanisms may impose limitations on the recovery of metacognitive knowledge after TBI. We also examined the extent to which these measures of awareness can predict dysexecutive behaviors. A sample of TBI patients (n=62) and their significant-others, provided reports of daily functioning post injury. In addition, patients underwent a neuropsychological assessment and were instructed to signal their errors during go/no-go tests. Interrelationships between metacognitive and emergent levels of awareness were examined, after controlling for the influence of secondary cognitive variables. Significant-other ratings correlated with errors made by the patients on neuropsychological tests but not with their premorbid function. Patients who under-reported daily life difficulties or over-reported their competency, compared to significant-other reports, were less likely to show awareness of laboratory errors. Emergent awareness was also identified as the sole predictor of performance on the modified six-element test, an ecologically valid test of multitasking. The online breakdown of error awareness after brain injury is related to difficulties with metacognitive awareness as reported in daily life, and is also predictive of dysexecutive behaviors. These findings are discussed in the context of multidimensional and neural models of awareness and error monitoring. (JINS, 2015,21, 473–482)
Food for thought: obstacles to menu labelling in restaurants and cafeterias
Authors: Thomas Erica 
Published: August 2015

AbstractMenu labelling is recommended as a policy intervention to reduce obesity and diet-related disease. The present commentary considers the many challenges the restaurant industry faces in providing nutrition information on its menus. Barriers include lack of nutrition expertise, time, cost, availability of nutrition information for exotic ingredients, ability to provide accurate nutrition information, libel risk, customer dissatisfaction, limited space on the menu, menu variations, loss of flexibility in changing the menu, staff training and resistance of employees to change current practice. Health promotion specialists and academics involved in fieldwork must help restaurateurs find solutions to these barriers for menu labelling interventions to be widely implemented and successful. Practical support for small independent restaurants such as free or subsidised nutrition analysis, nutrition training for staff and menu design may also be necessary to encourage voluntary participation.
Sustainable life support on Mars – the potential roles of cyanobacteria
Authors: Verseux Cyprien , Baqué Mickael , Lehto Kirsi , de Vera Jean-Pierre P. , Rothschild Lynn J. , Billi Daniela 
Published: August 2015

AbstractEven though technological advances could allow humans to reach Mars in the coming decades, launch costs prohibit the establishment of permanent manned outposts for which most consumables would be sent from Earth. This issue can be addressed byin situresource utilization: producing part or all of these consumables on Mars, from local resources. Biological components are needed, among other reasons because various resources could be efficiently produced only by the use of biological systems. But most plants and microorganisms are unable to exploit Martian resources, and sending substrates from Earth to support their metabolism would strongly limit the cost-effectiveness and sustainability of their cultivation. However, resources needed to grow specific cyanobacteria are available on Mars due to their photosynthetic abilities, nitrogen-fixing activities and lithotrophic lifestyles. They could be used directly for various applications, including the production of food, fuel and oxygen, but also indirectly: products from their culture could support the growth of other organisms, opening the way to a wide range of life-support biological processes based on Martian resources. Here we give insights into how and why cyanobacteria could play a role in the development of self-sustainable manned outposts on Mars.
Enabling sense-making for patients receiving outpatient palliative treatment: A participatory action research driven model for person-centered communication
Authors: Öhlén J. , Carlsson G. , Jepsen A. , Lindberg I. , Friberg F. 
Published: August 2015

ABSTRACTObjectives:In clinical palliative cancer care, the diversity of patient concerns over time makes information provision a critical issue, the demands of information-seeking patients presenting a challenge to both the communicative and organizational skills of the health provider. This study puts forward a practice model for communication between patients, their family members, and professional health providers during ongoing palliative chemotherapy; a model which supports the providers in enabling person-centered communication.Method:A constant comparative analysis adapted to participatory action research was applied. The model was developed step-wise in three interrelated cycles, with results from previous studies from palliative cancer care processed in relation to professional health providers' experience-based clinical knowledge. In doing this, focus group discussions were carried out with providers and patients to develop and revise the model.Results:The Enabling Sense Making model for person-centered communication gave rise to three domains (which are also the major communicative actors in palliative care): the patient, the family, and the provider. These actors were placed in the context of a communicative arena. The three respective domains were built up in different layers discriminating between significant aspects of person-centered communication, from the manifest that is most usually explicated in dialogues, to the latent that tends to be implicitly mediated.Significance of results:The model intends to facilitate timely reorientation of care from curative treatment or rehabilitation to palliation, as well as the introduction of appropriate palliative interventions over time during palliative phases. In this way the model is to be regarded a frame for directing the awareness of the professionals, which focuses on how to communicate and how to consider the patient’s way of reasoning. The model could be used as a complement to other strategic initiatives for the advancement of palliative care communication. It needs to be further evaluated in regard to practice evidence.
Assessment of discomfort in patients with cognitive failure in palliative care
Authors: Ferraz Gonçalves José António , Costa Elisabete , Edra Natércia , Gil João , Martinho Carla , Neves Emília , Peixoto Vânia , Rodrigues Andreia , Silva Margarida , Teixeira Sara 
Published: August 2015

AbstractObjective:When cognitive impairment precludes patients' report of symptoms, it becomes necessary to use other means. The purpose of our study was to evaluate the validity of the method currently in use on our service.Method:Two members of the team simultaneously assessed the patient and independently recorded whether the patient showed signs of discomfort, and a third questioned patients with cognitive failure who maintained some ability to respond if something was bothering them.Results:Some 200 assessments were made of 116 patients. The kappa coefficient of agreement was 0.615. The sensitivity was 17% and specificity 99%. The positive predictive value was 88%, and the negative predictive value was 73%.Significance of Results:Due to the low sensitivity of this method, it cannot be recommended as a screening tool.
The beginning of application of international humanitarian law: A discussion of a few challenges
Authors: Grignon Julia 
Published: August 2015

AbstractThis article discusses some of the challenges related to the beginning of application of international humanitarian law (IHL). It concludes that IHL pertaining to international armed conflicts begins to apply as soon as one State employs force in the territory of another State without the latter's consent, provided that the violence is of a collective nature. In the case of non-international armed conflicts, this article acknowledges that it is now well settled that the two key criteria are the organization of the parties to the conflict and the level of intensity of the violence. This article shows however that some of the challenges inherent to the beginning of application of IHL make it almost impossible to identify a very single point in time at which it begins to become applicable, be it for international armed conflicts, including occupation, or non-international armed conflicts.
mRIN for direct assessment of genome-wide and gene-specific mRNA integrity from large-scale RNA-sequencing data
Authors: Feng Huijuan , Zhang Xuegong , Zhang Chaolin 
Published: August 2015

AbstractThe volume of RNA-Seq data sets in public repositories has been expanding exponentially, providing unprecedented opportunities to study gene expression regulation. Because degraded RNA samples, such as those collected from post-mortem tissues, can result in distinct expression profiles with potential biases, a particularly important step in mining these data is quality control. Here we develop a method named mRIN to directly assess mRNA integrity from RNA-Seq data at the sample and individual gene level. We systematically analyse large-scale RNA-Seq data sets of the human brain transcriptome generated by different consortia. Our analysis demonstrates that 3′ bias resulting from partial RNA fragmentation in post-mortem tissues has a marked impact on global expression profiles, and that mRIN effectively identifies samples with different levels of mRNA degradation. Unexpectedly, this process has a reproducible and gene-specific component, and transcripts with different stabilities are associated with distinct functions and structural features reminiscent of mRNA decay in living cells.
Climate-mediated diversification of turtles in the Cretaceous
Authors: Nicholson David B. , Holroyd Patricia A. , Benson Roger B. J. , Barrett Paul M. 
Published: August 2015

AbstractChelonians are ectothermic, with an extensive fossil record preserved in diverse palaeoenvironmental settings: consequently, they represent excellent models for investigating organismal response to long-term environmental change. We present the first Mesozoic chelonian taxic richness curve, subsampled to remove geological/collection biases, and demonstrate that their palaeolatitudinal distributions were climate mediated. At the Jurassic/Cretaceous transition, marine taxa exhibit minimal diversity change, whereas non-marine diversity increases. A Late Cretaceous peak in ‘global’ non-marine subsampled richness coincides with high palaeolatitude occurrences and the Cretaceous thermal maximum (CTM): however, this peak also records increased geographic sampling and is not recovered in continental-scale diversity patterns. Nevertheless, a model-detrended richness series (insensitive to geographic sampling) also recovers a Late Cretaceous peak, suggesting genuine geographic range expansion among non-marine turtles during the CTM. Increased Late Cretaceous diversity derives from intensive North American sampling, but subsampling indicates that Early Cretaceous European/Asian diversity may have exceeded that of Late Cretaceous North America.
Hail formation triggers rapid ash aggregation in volcanic plumes
Authors: Van Eaton Alexa R. , Mastin Larry G. , Herzog Michael , Schwaiger Hans F. , Schneider David J. , Wallace Kristi L. , Clarke Amanda B. 
Published: August 2015

AbstractDuring explosive eruptions, airborne particles collide and stick together, accelerating the fallout of volcanic ash and climate-forcing aerosols. This aggregation process remains a major source of uncertainty both in ash dispersal forecasting and interpretation of eruptions from the geological record. Here we illuminate the mechanisms and timescales of particle aggregation from a well-characterized ‘wet’ eruption. The 2009 eruption of Redoubt Volcano, Alaska, incorporated water from the surface (in this case, a glacier), which is a common occurrence during explosive volcanism worldwide. Observations from C-band weather radar, fall deposits and numerical modelling demonstrate that hail-forming processes in the eruption plume triggered aggregation of ∼95% of the fine ash and stripped much of the erupted mass out of the atmosphere within 30 min. Based on these findings, we propose a mechanism of hail-like ash aggregation that contributes to the anomalously rapid fallout of fine ash and occurrence of concentrically layered aggregates in volcanic deposits.
Flexible lithium–oxygen battery based on a recoverable cathode
Authors: Liu Qing-Chao , Xu Ji-Jing , Xu Dan , Zhang Xin-Bo 
Published: August 2015

AbstractAlthough flexible power sources are crucial for the realization next-generation flexible electronics, their application in such devices is hindered by their low theoretical energy density. Rechargeable lithium–oxygen (Li–O2) batteries can provide extremely high specific energies, while the conventional Li–O2 battery is bulky, inflexible and limited by the absence of effective components and an adjustable cell configuration. Here we show that a flexible Li–O2 battery can be fabricated using unique TiO2 nanowire arrays grown onto carbon textiles (NAs/CT) as a free-standing cathode and that superior electrochemical performances can be obtained even under stringent bending and twisting conditions. Furthermore, the TiO2 NAs/CT cathode features excellent recoverability, which significantly extends the cycle life of the Li–O2 battery and lowers its life cycle cost.
Detection of entanglement in asymmetric quantum networks and multipartite quantum steering
Authors: Cavalcanti D. , Skrzypczyk P. , Aguilar G. H. , Nery R. V. , Ribeiro P.H. Souto , Walborn S. P. 
Published: August 2015

AbstractThe future of quantum communication relies on quantum networks composed by observers sharing multipartite quantum states. The certification of multipartite entanglement will be crucial to the usefulness of these networks. In many real situations it is natural to assume that some observers are more trusted than others in the sense that they have more knowledge of their measurement apparatuses. Here we propose a general method to certify all kinds of multipartite entanglement in this asymmetric scenario and experimentally demonstrate it in an optical experiment. Our results, which can be seen as a definition of genuine multipartite quantum steering, give a method to detect entanglement in a scenario in between the standard entanglement and fully device-independent scenarios, and provide a basis for semi-device-independent cryptographic applications in quantum networks.