bluuebunny/crossref_metadata_2025_split huggingface dataset:
SEOM-GEICO Clinical Guidelines on cervical cancer (2023)
Authors: Manso Luis , Ramchandani-Vaswani Avinash , Romero Ignacio , Sánchez-Lorenzo Luisa , Bermejo-Pérez María José , Estévez-García Purificación , Fariña-Madrid Lorena , García García Yolanda , Gil-Martin Marta , Quindós María 
Published: August 2024

AbstractCervical cancer (CC) is the fourth most common cancer and the fourth leading cause of mortality in women worldwide. It is strongly associated with high-risk human papillomavirus infection. High-income countries that have implemented human papillomavirus (HPV) vaccination and screening programs have seen dramatic reductions in CC incidence, while developing countries where these programs are not available continue to experience high rates of CC deaths. In early-stage CC, the primary treatment is surgery or radiotherapy, whereas concurrent chemo-radiotherapy (CRT) remains the conventional approach in locally advanced stages until the upcoming approval of immunotherapy. The incorporation of immunotherapy in combination with chemotherapy (with or without bevacizumab) in first line and as monotherapy in second line after platinum-based chemotherapy, has significantly increased overall survival (OS) in recurrent or metastatic CC. The purpose of this guideline is to summarize the most relevant evidence in the diagnosis, treatment, and follow-up of CC and to provide evidence-based recommendations for clinical practice.
In need of improvement: archaeological evidence of river management in South-Eastern Australia
Authors: Lawrence Susan , Davies Peter 
Published: August 2024

AbstractPatterns of river modification since settler invasion of southern Australia are the product of a specific set of deep-seated and implicit cultural values concerning the purpose and function of waterways. Rivers have been dammed, diverted, dredged and straightened to meet a range of human needs and objectives. Such changes are routinely described as ‘improvements’ but there is a lack of critical engagement with what ‘improvement’ might mean. Interventions carried out initially on an ad hoc basis, and later more systematically with state support, collectively shed light on the persistent underlying drive to ‘Improve’ nature and society that has permeated Western thought since the Enlightenment. Here we use the example of one river system, the Loddon, to analyse ways in which Improvement intersected with settler engagement with Australian rivers. We argue that settler interventions have been informed by a consistent set of understandings about the purpose of rivers. The characteristics of water management infrastructure along the Loddon reveal how the river fell short of the settler-colonial ideal and why they thought it needed to be Improved at all.
Monitoring climate change vulnerability in the Himalayas
Authors: Malik Ishfaq Hussain , Ford James D. 
Published: August 2024

AbstractLongitudinal assessment of climate vulnerability is essential for understanding the complex factors affecting how people experience and respond to climate change. We report on the first longitudinal assessment of climate vulnerability in the Himalayan region, exploring the evolving landscape, perceptions, and experiences of communities of climate change impacts, vulnerability, and adaptation in Kashmir over an 8-year period from 2017 to 2024. We provide the Himalayan Re-study Framework (HRF) to monitor, characterise, and conceptualise climate change in the Himalayas. Utilising mixed methods, we showcase how climate change is affecting social, economic, political, and environmental dimensions, examining how the impacts of climate change and vulnerability evolve over time, shaping and reshaping how climate risks are experienced and responded to by communities. Our analysis reveals a nuanced understanding of vulnerability, highlighting the impact on communities’ livelihoods and water security, differential impacts on marginalised communities, and the gendered nature of climate change. We examine how certain sections of the population face marginalisation, discrimination, and racism, and how climate change exacerbates these challenges. Kashmir’s vulnerability to climate change extends beyond environmental factors, intertwining with culture, livelihoods, social dynamics, and politics. Climate change continues to compete for attention with immediate political and socio-economic challenges, highlighting the need for integrated approaches to address both environmental and societal issues in Kashmir.
Advanced Respiratory Monitoring in the Perioperative Setting
Authors: Jimenez-Santana Jose Daniel , Spadaro Savino , Argente Navarro Maria Pilar , Mazzinari Guido 
Published: August 2024

Abstract
Purpose of Review
This narrative review explores the technical principles and evidence supporting the use of advanced respiratory monitoring tools in the perioperative setting to enhance patient care. We aim to identify which patients benefit most from these technologies during major surgeries.

Recent Findings
Advanced monitoring techniques, such as electrical impedance tomography (EIT), esophageal pressure (Pes) monitoring, and lung ultrasound (LUS), provide detailed insights into lung mechanics and function. Recent studies indicate these tools can optimize ventilation strategies by individualizing the lung protective ventilation, particularly in high-risk patients.

Summary
While these tools can help to improve intraoperative respiratory mechanics and oxygenation, further randomized clinical trials are needed to confirm their impact on patient-centered outcomes.
Parental styles are associated with eating disorder symptoms, anxiety, interpersonal difficulties, and nucleus accumbens response
Authors: Sahota Neha , Shott Megan E. , Frank Guido K. W. 
Published: August 2024

Abstract
Objectives
Eating disorders (EDs) typically emerge during adolescence. Parental bonding has a lasting impact on a child’s mental health during those developmentally critical years. There remains uncertainty over whether parental bonding is a risk factor for developing or maintaining specifically EDs or, rather, general psychopathology and the associated underlying brain function.

Methods
Forty-one young adult healthy control individuals (HC, 26.6 ± 3.5 years) and 46 individuals with EDs (25 with anorexia nervosa, AN, 22.8 ± 6.4 years, and 21 with bulimia nervosa, BN, 23.5 ± 4.2 years) completed the parental bonding instrument (PBI), assessments for anxiety, depression, and ED behaviors, and underwent a conditioning paradigm during brain imaging.

Results
In both groups, perceived parental care and overprotection were correlated with state and trait anxiety and interpersonal alienation, and in HC only, with body dissatisfaction and drive for thinness. Individuals with an ED reported lower self-perceived parental care, but higher overprotection compared to the HC group. Nucleus accumbens (NAc) response was related to bonding measures in both groups and right NAc response mediated the relationship between maternal care and trait anxiety in HC.

Conclusions
Perceived parental bonding is associated with general psychopathology, including elevated anxiety and interpersonal difficulties across HC and ED groups. Lower perceived parental care and higher overprotection could predispose healthy individuals to develop problems with body shape or weight; however, other, maybe biological factors may determine whether a person will develop an ED. The link between perceived parental bonding, NAc valence processing and anxiety implicates dopaminergic circuits that should be studied further.
Level of Evidence: Level III: Case–control analytic study
On the fractional heat semigroup and product estimates in Besov spaces and applications in theoretical analysis of the fractional Keller–Segel system
Authors: Pérez-López Jhean E. , Rueda-Gómez Diego A. , Villamizar-Roa Élder J. 
Published: August 2024

AbstractThis paper is concerned with the fractional Keller–Segel system in temporal and spatial variables. We consider fractional dissipation for the physical variables including a fractional dissipation mechanism for the chemotactic diffusion, as well as a time fractional variation assumed in the Caputo sense. We analyze the fractional heat semigroup obtaining time decay and integral estimates of the Mittag–Leffler operators in critical Besov spaces, and prove a bilinear estimate derived from the nonlinearity of the Keller–Segel system, without using auxiliary norms. We use these results in order to prove the existence of global solutions in critical homogeneous Besov spaces employing only the norm of the natural persistence space, including the existence of self-similar solutions, which constitutes a persistence result in this framework. In addition, we prove a uniqueness result without assuming any smallness condition on the initial data.
Communication Preferences and Factors Predicting Smartphone Addiction Among Four Generations of Australians: Gender and Generational Differences
Authors: Belic Ivanka , Winskel Heather , Allen Kachina , Longstaff Mitchell Grant 
Published: August 2024

AbstractSmartphones are commonly used for socializing, entertainment, and information-seeking. However, excessive and problematic usage may lead to smartphone addiction, which is linked to cognitive and attentional deficits and mental health issues globally. Historically, age and gender have been found to influence smartphone usage. Furthermore, the relationship between communication preferences (via mobile-technology versus in-person) and usage, and addictive tendencies is understudied. Past research has seldom explored older age groups. This study investigates generational (“Gen-Z,” “Gen-X,” “Gen-Y,” and Baby-Boomers) and gender differences in smartphone usage, communication preferences, and factors predicting smartphone addiction scores (SAS). The study surveyed 894 adults aged 18–80 years to examine interpersonal communication preferences, daily hours of smartphone usage, and SAS. Participants were recruited via snowball sampling through digital and printed media. Daily hours of usage and SAS were closely related and shown to reduce after the age of 40 years. Generations “Z” and “Y” reported the highest daily use and scored higher in SAS than the older generations. Women scored higher in SAS than men in all generations except “Gen-X.” Age, hours of usage, and preference for mobile communication predicted SAS, but gender did not. Overall, people prefer to communicate with others in-person more than via mobile-technology. The findings identify significant generational and gender differences in daily usage, addiction scores, and communication preferences. Preference to communicate more via mobile-technology than in-person predicted SAS. Future research needs to investigate smartphone usage among all age groups and genders to clarify the risks and protective factors associated with smartphone addiction.
A proactive grey wolf optimization for improving bioinformatic systems with high dimensional data
Authors: Alsaeedi Ali Hakem , Al-Shammary Dhiah , Hadi Suha Mohammed , Ahmed Khandakar , Ibaida Ayman , AlKhazraji Nooruldeen 
Published: August 2024

AbstractThis paper introduces a new methodology for optimization problems, combining the Grey Wolf Optimizer (GWO) with Simi-stochastic search processes. Intelligent optimizations represent an advanced approach in machine learning and computer applications, aiming to reduce the number of features used in the classification process. Optimizing bioinformatics datasets is crucial for information systems that classify data for intelligent tasks. The proposed A-Proactive Grey Wolf Optimization (A-GWO) solves stagnation in GWO by applying a dual search with a Simi-stochastic search. This target is achieved by distributing the population into two groups using a different search technique. The model's performance is evaluated using two benchmarks: the Evolutionary Computation Benchmark (CEC 2005) and seven popular biological datasets. A-GWO demonstrates highly improved efficiency in comparision to the original GWO and Particle Swarm Optimization (PSO). Specifically, it enhances exploration in 66% of CEC functions and achieves high accuracy in 70% of biological datasets.
The Past and Future of the Fisheries and Marine Ecosystem Model Intercomparison Project
Authors: Novaglio Camilla , Bryndum‐Buchholz Andrea , Tittensor Derek P. , Eddy Tyler D. , Lotze Heike K. , Harrison Cheryl S. , Heneghan Ryan F. , Maury Olivier , Ortega‐Cisneros Kelly , Petrik Colleen M. , Roberts Kelsey E. , Blanchard Julia L. 
Published: August 2024

AbstractClimate change is increasingly affecting the world's ocean ecosystems, necessitating urgent guidance on adaptation strategies to limit or prevent catastrophic impacts. The Fisheries and Marine Ecosystem Model Intercomparison Project (FishMIP) is a network and framework that provides standardised ensemble projections of the impacts of climate change and fisheries on ocean life and the benefits that it provides to people. Since its official launch in 2013 as a small, self‐organized project within the larger Inter‐Sectoral Impact Model Intercomparison Project, the FishMIP community has grown substantially and contributed to key international policy processes, such as the Intergovernmental Panel on Climate Change Assessment Report, and the Intergovernmental Science‐Policy Platform on Biodiversity and Ecosystem Services Global Biodiversity Assessment. While not without challenges, particularly around comparing heterogeneous ecosystem models, integrating fisheries scenarios, and standardising regional‐scale ecosystem models, FishMIP outputs are now being used across a variety of applications (e.g., climate change targets, fisheries management, marine conservation, Sustainable Development Goals). Over the next decade, FishMIP will focus on improving ecosystem model ensembles to provide more robust and policy‐relevant projections for different regions of the world under multiple climate and societal change scenarios, and continue to be open to a broad spectrum of marine ecosystem models and modelers. FishMIP also intends to enhance leadership diversity and capacity‐building to improve representation of early‐ and mid‐career researchers from under‐represented countries and ocean regions. As we look ahead, FishMIP aims to continue enhancing our understanding of how marine life and its contributions to people may change over the coming century at both global and regional scales.
Isotropic High‐Frequency Radiation in Near‐Fault Seismic Data
Authors: Ben‐Zion Yehuda , Zhang Siyuan , Meng Xiaofeng 
Published: August 2024

AbstractWe compare Fourier Amplitude Spectra of Fault Normal (FN) and Fault Parallel (FP) seismograms at near‐fault sites for seven strike‐slip earthquakes with moment magnitudes Mw ≥ 6. For all events we find large FN/FP ratios at low frequencies consistent with near‐fault S‐wave radiation patterns for strike‐slip earthquakes. However, the difference diminishes with increasing frequency and FN/FP is about 1 above a transition frequency. The results may reflect small tensile/isotropic components in the earthquake rupture zones that homogenize the high‐frequency radiation in different directions at near‐fault sites. The FN/FP ratios at low frequencies and transition frequencies above which FN ∼ FP vary among the analyzed earthquakes and have no clear correlation with the magnitudes. The lack of correlation may signify a characteristic scale (e.g., process zone size, duration of source time function) controlling the isotropic radiation, and/or wave propagation and other effects that mask the source effects.
RegionGrow3D: A Deterministic Analysis for Characterizing Discrete Three‐Dimensional Landslide Source Areas on a Regional Scale
Authors: Mathews Nicolas W. , Leshchinsky Ben A. , Mirus Benjamin B. , Olsen Michael J. , Booth Adam M. 
Published: August 2024

AbstractRegional‐scale characterization of shallow landslide hazards is important for reducing their destructive impact on society. These hazards are commonly characterized by (a) their location and likelihood using susceptibility maps, (b) landslide size and frequency using geomorphic scaling laws, and (c) the magnitude of disturbance required to cause landslides using initiation thresholds. Typically, this is accomplished through the use of inventories documenting the locations and triggering conditions of previous landslides. In the absence of comprehensive landslide inventories, physics‐based slope stability models can be used to estimate landslide initiation potential and provide plausible distributions of landslide characteristics for a range of environmental and forcing conditions. However, these models are sometimes limited in their ability to capture key mechanisms tied to discrete three‐dimensional (3D) landslide mechanics while possessing the computational efficiency required for broad‐scale application. In this study, the RegionGrow3D (RG3D) model is developed to broadly simulate the area, volume, and location of landslides on a regional scale (≥1,000 km2) using 3D, limit‐equilibrium (LE)‐based slope stability modeling. Furthermore, RG3D is incorporated into a susceptibility framework that quantifies landsliding uncertainty using a distribution of soil shear strengths and their associated probabilities, back‐calculated from inventoried landslides using 3D LE‐based landslide forensics. This framework is used to evaluate the influence of uncertainty tied to shear strength, rainfall scenarios, and antecedent soil moisture on potential landsliding and rainfall thresholds over a large region of the Oregon Coast Range, USA.
Digital consults in heart failure care: a randomized controlled trial
Authors: Man Jelle P. , Koole Maarten A. C. , Meregalli Paola G. , Handoko M. Louis , Stienen Susan , de Lange Frederik J. , Winter Michiel M. , Schijven Marlies P. , Kok Wouter E. M. , Kuipers Dorianne I. , van der Harst Pim , Asselbergs Folkert W. , Zwinderman Aeilko H. , Dijkgraaf Marcel G. W. , Chamuleau Steven A. J. , Schuuring Mark J. 
Published: August 2024

AbstractGuideline-directed medical therapy (GDMT) has clear benefits on morbidity and mortality in patients with heart failure; however, GDMT use remains low. In the multicenter, open-label, investigator-initiated ADMINISTER trial, patients (n = 150) diagnosed with heart failure and reduced ejection fraction (HFrEF) were randomized (1:1) to receive usual care or a strategy using digital consults (DCs). DCs contained (1) digital data sharing from patient to clinician (pharmacotherapy use, home-measured vital signs and Kansas City Cardiomyopathy Questionnaires); (2) patient education via a text-based e-learning; and (3) guideline recommendations to all treating clinicians. All remotely gathered information was processed into a digital summary that was available to clinicians in the electronic health record before every consult. All patient interactions were standardly conducted remotely. The primary endpoint was change in GDMT score over 12 weeks (ΔGDMT); this GDMT score directly incorporated all non-conditional class 1 indications for HFrEF therapy with equal weights. The ADMINISTER trial met its primary outcome of achieving a higher GDMT in the DC group after a follow-up of 12 weeks (ΔGDMT score in the DC group: median 1.19, interquartile range (0.25, 2.3) arbitrary units versus 0.08 (0.00, 1.00) in usual care; P < 0.001). To our knowledge, this is the first multicenter randomized controlled trial that proves a DC strategy is effective to achieve GDMT optimization. ClinicalTrials.gov registration: NCT05413447.
Exploring alternative fuel solutions: lemon grass oil biodiesel blend with dibutyl ether additive for VCR diesel engines - an experimental analysis
Authors: Paramasivam Prabhu , Balasubramanian Arun , Adeleke Adekunle Akanni , Ikubanni Peter Pelumi , Kumar Sandeep , Prakash Chander , Kumar Rahul 
Published: August 2024

AbstractThere has been an intense surge in interest in the search for alternative sources of petroleum fuels in the modern world as a result of the inflation of fuel prices and the historic supply gap. When compared to petroleum fuels, biodiesel is becoming an increasingly valuable option due to the fact that it produces less emissions and provides the almost same amount of energy. In point of fact, the prime aim of this work is to explore the possibility of utilizing biodiesel derived from lemongrass oil and including dibutyl ether as an additive for the test diesel engine operating on varied compression ratios. The findings showed that the best operating settings are a 17.5 compression ratio with a blend of 30% biodiesel and 70% diesel fuel. At greater loads, brake thermal efficiency is lower than that of diesel engines. Lower loads result in lower specific fuel usage. Mechanical efficiency at higher loads is highest in the B30 blend, but emission metrics such as CO, CO2, HC, and NOx were reduced with the inclusion of an additive, though HC rose with higher loads of lemongrass oil biodiesel blends. When compared to the B30 biodiesel blend with various composition additives, the B30 + 4% additive has the highest efficiency at the fourth load in terms of both brake power and mechanical efficiency.
Performance analysis of high voltage disc insulators with different profiles in clean and polluted environments using flashover, withstand voltage tests and finite element analysis
Authors: Ali Arfan , Bhatti Abdul Rauf , Rasool Akhtar , Rehman Fazal Ur , Khan Muhammad Amjad , Ali Ahmed , Sherefa Abdulkerim 
Published: August 2024

AbstractSevere pollution-induced flashovers on insulators present a pressing challenge to power system safety. The frequent failure of high-voltage insulators, particularly in the polluted environments of Pakistan, poses a critical concern. This paper investigates the impact of insulator profile on reducing pollution flashovers, testing two designs as per IEC standard 60383 and simulated using the Finite Element Method in COMSOL Multiphysics®. The test results revealed that deep under-ribs insulators exhibited a 5.008% reduction in flashover voltage, while alternating shed insulators experienced a 3.233% decrease in polluted conditions compared to clean conditions. Notably, under both clean and polluted conditions, alternating shed insulators consistently outperformed deep under-ribs insulators, with a 25.377% higher flashover voltage in clean conditions and a 27.400% superiority in polluted conditions. Computational analysis through the Finite Element Method in COMSOL Multiphysics shows a consistent pattern in potential distribution with increasing insulator count, but the presence of a pollution layer introduces spikes in the electric field distribution, validating experimental results. These findings highlight the superior performance of alternating shed insulators, especially in polluted environments.