bluuebunny/crossref_metadata_2025_split huggingface dataset:
Intracranial ependymomas in pediatric patients: patterns of care, disparities, and survival outcomes from the National Cancer Database
Authors: Jagtiani Pemla , Karabacak Mert , Le Chi , Bahadir Zeynep , Morgenstern Peter F. , Margetis Konstantinos 
Published: August 2024

OBJECTIVE
This study aimed to extract and analyze comprehensive data from the National Cancer Database (NCDB) to gain insights into the epidemiological prevalence, treatment patterns, and survival outcomes associated with intracranial ependymomas in pediatric patients.

METHODS
The authors examined data extracted from the NCDB spanning the years 2010 to 2017, with a specific emphasis on intracranial ependymomas in individuals aged 0–21 years. The study used logistic and Poisson regression, along with Kaplan-Meier survival estimates and Cox proportional hazards models, for analysis.

RESULTS
Among 908 included pediatric patients, 495 (54.5%) were male, and 702 (80.6%) were White. Kaplan-Meier analysis determined overall survival (OS) rates of 97.1% (95% CI 96%–98.2%) at 1 year postdiagnosis, 89% (95% CI 86.9%–91.1%) at 3 years, 82.9% (95% CI 80.3%–85.7%) at 5 years, and 74.5% (95% CI 69.8%–79.4%) at 10 years. Grade 3 tumors predicted a more than fourfold higher mortality hazard (p < 0.001; reference = grade 2). Infratentorial localization was also associated with a 1.7-fold increase in mortality hazard (p = 0.002; reference = supratentorial). Larger maximum tumor size (> 5 cm) correlated with a lower mortality hazard (HR 0.64, p = 0.011; reference ≤ 5 cm). The vast majority of patients (85.9%, n = 780) underwent resection. Uninsured patients had over fourfold higher prolonged length of stay (LOS) odds than those privately insured (OR 4.645, p = 0.007). Radiotherapy was received by 76.1% of patients, and the highest rates of radiotherapy occurred among children aged 5–12 years (p < 0.001). Only 25.6% received chemotherapy at any point during their treatment. Peak chemotherapy use emerged within ages 0–4 years, reaching 33.6% in this age group. Kaplan-Meier analysis indicated chemotherapy was associated with significantly worse OS (p = 0.041).

CONCLUSIONS
This comprehensive analysis of the NCDB provides valuable insights into the epidemiology, treatment patterns, and survival outcomes of intracranial ependymomas in pediatric patients. Higher tumor grade, infratentorial localization, and chemotherapy use was associated with worse OS, while larger tumor size correlated with lower mortality hazard. Disparities in care were identified, with uninsured patients experiencing prolonged LOS. These findings underscore the need for tailored treatment strategies based on patient and tumor characteristics and highlight the importance of addressing socioeconomic barriers to optimize outcomes for children with ependymomas.
Minimally invasive posterior cervical foraminotomy versus the anterior transcorporeal approach for cervical radiculopathy: a systematic review and meta-analysis
Authors: Rajjoub Rami , Nguyen Ryan , Ghaith Abdul Karim , El-Hajj Victor Gabriel , De Biase Gaetano , Onyedimma Chiduziem , Yolcu Yagiz U. , Jarrah Ryan , Elmi-Terander Adrian , Akinduro Oluwaseun O. , Abode-Iyamah Kingsley , Bydon Mohamad 
Published: August 2024

OBJECTIVE
Surgical decompression is often indicated for symptomatic cases of cervical radiculopathy. In the cervical spine, minimally invasive posterior cervical foraminotomy (MIS-PCF) and the anterior transcorporeal approach (ATCA) are modern techniques available to surgeons. This systematic review and single-arm meta-analysis aimed to assess surgical and patient-reported outcomes of MIS-PCF and ATCA for cervical radiculopathy.

METHODS
A systematic review of the literature was conducted using 1) Ovid; 2) Epub Ahead of Print and In-Process, In-Data-Review & Other Non-Indexed Citations; and 3) Scopus databases, which reported outcomes following cervical decompression using MIS-PCF or the ATCA. Specifically, baseline characteristics, operative outcomes, and changes in visual analog scale (VAS) neck pain score were assessed. The quality of the studies was graded using the modified Newcastle-Ottawa Scale for observational studies.

RESULTS
Forty studies with 1661 patients were identified. The comparative analysis of both techniques revealed no significant differences in complication (7%, 95% CI 5%–10%, p = 0.75) or reoperation rates (5%, 95% CI 3%–7%, p = 0.41). Additionally, there were no significant differences in estimated blood loss (55.39, 95% CI 44.62–66.16 ml, p = 0.55) or operative time (85.15, 95% CI 65.38–104.92 minutes, p = 0.05). The ATCA showed significantly greater improvement (p < 0.01) in VAS neck pain scores following surgery (ATCA point reduction 6.7, 95% CI 6.0–7.5 points vs MIS-PCF 3.0, 95% CI 1.0–5.0 points).

CONCLUSIONS
The ATCA and MIS-PCF are effective modern techniques for the surgical treatment of radiculopathy. Both approaches showed comparable postoperative outcomes, including complication and reoperation rates. However, the ATCA was shown to provide significantly greater improvement in VAS neck pain scores.
EXPLORING INDONESIAN EFL PRE-SERVICE TEACHERS’ PROFESSIONAL IDENTITY
Authors: Andana Yosi , Fithriani Rahmah 
Published: August 2024

Professional identity refers to the self-perception that is related to work. Personal professional identity influences behavior and actions in the work environment. A strong impression of professional identity causes individuals to act in accordance with the norms, ethics, and standards of their profession. Professional identity is an inseparable concept in all professions including the teaching profession. Although much research has examined teachers' professional identity, research on prospective teachers who are still in training is still limited. Many researches emphasis identity among qualified teachers with the assumption that they have a more established identity compared to pre-service teachers who are still developing their professional identities. Acknowledging its importance may encourage further research and contribute to a broader understanding of teacher development, which is informed by knowledge of what factors influence professional identity at all levels. Qualitative descriptive approach is employed in this study. The study is conducted on 13 pre-service teachers majoring in English education who have had field teaching experience. The research instruments used are questionnaires, in-depth interviews, and literature research. Then the data is analyzed using thematic analysis. The findings indicate a crucial factor in the establishing of pre-service teachers' professional self-concept, namely the initial motivation when choosing an English education major. Pre-service teachers also expressed an awareness of the role of professional identity in enabling effective professional performance. Additionally, holding positive perspectives about their chosen profession appears to support skills development that provides new perspectives to the preparation of expert teachers
Pengaruh Return on Asset (ROA) dan Debt to Asset Ratio (DAR) Terhadap Harga Saham Pada PT. Ultrajaya Milk Industry, Tbk.
Authors: Firman Firda Milani , Nurhayati Nurhayati , M.Rimawan  
Published: August 2024

Studi ini akan mempelajari pengaruh Retrun On Asset (ROA) dan Debt To Asset Rasio (DAR) terhadap harga saham PT. Industri Susu Ultrajaya, Tbk. Kedua faktor tersebut berdampak pada harga saham PT. Industri Susu Ultrajaya, Tbk. Data akan dikumpulkan dari laporan keuangan yang terdaftar di Bursa Efek Indonesia (BEI) dari tahun 1990 hingga 2022 atau 32 tahun. Metode yang digunakan dalam penelitian ini adalah metode asosiatif dan pengambilan sampel adalah metode purposive sampel akan digunakan pada tahun 2013-2022 atau 10 tahun. Profitabilitas (ROA) dan solvabilitas (DAR) digunakan sebagai analisis rasio atau kinerja keuangan dalam penelitian ini. Bagaimana variabel keterikatan dan variabel bebas berinteraksi satu sama lain juga ditentukan oleh analisis statistik. Hipotesis klasik pertama kali diuji. Untuk memastikan bahwa data tidak menunjukkan heteroskadasitas atau multikoliniaritas, penelitian ini menggunakan metode analisis regresi linier berganda. Uji T, uji F, dan koefisien determinasi digunakan untuk memastikan bahwa distribusi data normal dan tidak terdapat gejala heteroskadasitas atau multikoliniaritas. Hasil penelitian menunjukkan bahwa harga saham PT. Ultrajaya Milk Industry, Tbk Return On Asset (ROA) dan Debt To Aset Ratio (DAR) berpengaruh signifikan secara parsial terhadap harga saham pada PT. Ultrajaya Milk Industry, Tbk. Namun rasio hutang ke aset Retrun On Asset (ROA) tidak mempengaruhi harga saham (penutupan) pada PT. Ultrajaya Milk Industry, Tbk.
Faktor Yang Berhubungan Dengan Perilaku Ibu Dalam Pemberian MP-ASI Pada Bayi Usia 6-12 Bulan
Authors: Nurmadiyah Nurmadiyah , Permanasari Ika , Efliani Destria 
Published: August 2024

<p class="node"><em><strong>Background: </strong>Complementary feeding is the transition from milk intake to semi-solid food. </em><em>Complementary feeding must be introduced at the right time, be adequate, safe, and well-fed as this stage significantly impacts the health and optimal growth of the baby.</em><em> Factors related to complementary feeding include family support, education, cultural, and technological factors. The aim of this research was to identify factors associated with maternal behaviour in providing complementary foods to babies aged 6–12 months in Batu Ampar Village. The design of this research was a cross-sectional study conducted in September 2023. The population and sample in this study consisted of all babies aged 6–12 months in Batu Ampar Village, totalling 47 individuals. Data were obtained from the questionnaire sheet. The data analysis used in this study was cross-sectional. The research results showed that out of 47 respondents, 21 (44.7%) had senior high school education, 29 (61.7%) reported good family support, and 29 (61.7%) indicated having a good cultural background. Additionally, 29 respondents (61.7%) used technology to provide supplementary breast milk to their babies. The results of the analysis indicate a relationship between education (p-value = 0.02), culture (p-value = 0.04), and family support (p-value = 0.018) and the behaviour of providing complementary feeding. There is no significant relationship between technology and the behaviour of providing complementary feeding (p-value = 0.102). It is recommended that health workers and families provide support and motivation to encourage caregivers to practice complementary.</em></p><p class="node"><em> </em></p>
Antioxidant Effects and Fatty Acid Analysis of Leucojum aestivum Seed Coat Extracts
Authors: Uysal Demet İncedere , Çolak Esin , Aytar Erdi Can , Durmaz Alper , Şentürk Bengisu , Torunoğlu Emine İncilay , Özdener Kömpe Yasemin 
Published: August 2024

The aim of this study is to analyze the biochemical composition and antioxidant activity of Leucojum aestivum seed coats. In the crude extract the total phenolic content was determined to be 129.55 ± 1.94 mg gallic acid equivalent (GAE)/g, while the total flavonoid content was found to be 210.21 ± 7.91 mg quercetin equivalent (QE)/g. Additionally, the total flavonol, tannin, and proanthocyanidin contents were determined to be 9.63 ± 5.16 mg QE/g, 3.32 ± 0.14 mg GAE/g, and 129.89 ± 6.10 mg catechin equivalent (CAE)/g, respectively. Furthermore, the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity showed a significant antioxidant potential with a concentration that results in 50% decrease in the initial DPPH concentration IC50 value of 214.97 ± 50.44 mg QE/g in the crude extract. GC/MS analysis revealed the presence of various biologically active compounds, including hexadecanoic acid, oleic acid, and stigmasterol. Moreover, galantamine and galathan were identified in the seed coat extracts. Fatty acid analysis indicated the presence of compounds such as linoleic acid, oleic acid, and palmitic acid. This comprehensive study provides a detailed examination of seed coats and highlights the presence of biologically active compounds such as galantamine. This finding represents a study conducted for the first time in the literature, as no similar research focusing on L. aestivum seed coats has been conducted previously. Therefore, the results of the study provide new insights into the potential biological and pharmacological effects of seed coats and offer significant findings that could serve as a basis for future research.
AN ANALYSIS OF METAPHOR TRANSLATION IN A NOVEL ENTITLED SITI NURBAYA BY MARAH RUSLI
Authors: Rahayu Sarah Siti , Pardede Jannes Freddy 
Published: August 2024

Siti Nurbaya is one of the well-known works of Indonesian literature. This novel was written by Marah Rusli in 1922 and has been translated into various languages, one of which is translated into English. In literary works, especially old literary works, the use of figurative language is often found, one of which is metaphor. This research will discuss the translation of live and dead metaphors from the source language to the target language. Translating metaphor is one of the subs of literary translation. This research using qualitative method to analyze the novel and find the results of live and dead metaphor translation. The research of this live and dead metaphor using theory from Na’imah (2017). The results of this research is there are live and dead metaphors found in this novel. Even some of the translation is equivalent in meaning with the source language, but some are not equivalent. After analyzing the live and dead metaphors, researcher also analyze the metaphor translation strategies that used by translator to translate the metaphors from SL (Source Language) to TL (Target Language). The results of the translation strategies used by translator are based on Newmark's theory. This translator uses 4 of the 7 strategies proposed by Newmark. In this study the researcher also found metaphor translation strategies used by translator to translate metaphors from the source language to the target language. Based on the analysis using Newmark's theory, this translator uses 4 of the 7 strategies proposed by Newmark. They are reproducing, replacing the image, translating metaphors by simile, and translating metaphors by simile and senses.
Evolução da internação por infarto agudo do miocárdio no Brasil entre 2008 e 2023
Authors: Rangel Tura Bernardo , dos Reis von Doellinger Vanessa 
Published: August 2024

A presente nota técnica analisa as tendências das internações hospitalares por infarto agudo do miocárdio (IAM) no Brasil, utilizando dados do Sistema de Internação Hospitalar. O estudo observacional abrange 1.729.543 internações, destacando variações demográficas, incluindo idade e sexo dos pacientes.
A idade média dos internados por IAM aumentou 1,8 anos no período estudado. Internações de pacientes jovens (até 40 anos) também foram analisadas, mostrando um aumento numérico, mas sem mudanças significativas na proporção.
A análise da série temporal, utilizando modelos ARIMA, revelou tendências sazonais e o impacto significativo da pandemia de COVID-19, resultando em uma redução estimada de 22.646 internações por IAM durante a pandemia. Além disso, foi observada uma relação entre as estações do ano e as internações por IAM, com picos no inverno.
Os resultados sublinham a importância de políticas de saúde pública direcionadas, prevenção e otimização do atendimento aos pacientes com IAM. A análise fornece uma base sólida para futuras estratégias de saúde para reduzir a morbimortalidade associada ao IAM no Brasil.
Sugarcane sustainability in a changing climate: a systematic review on pests, diseases, and adaptive strategies
Authors: Msomba Bahati Hakimu , Ndaki Patrick Madulu , Joseph Charles O. 
Published: August 2024

The cultivation of sugarcane (Saccharum officinarum L.) in the face of climate change requires robust strategies for managing pests, diseases, and weeds. This systematic review exposes critical deficiencies in current practices and underscores the need for climate-adaptive strategies. Climate change differentially influences pest behaviour, disease progression, and weed growth across various regions, yet the lack of region-specific responses impairs effective management. The review emphasizes the necessity for localized approaches that consider specific climatic conditions and the development of predictive models to anticipate pest and disease outbreaks. These models include Decision Support Systems (DSS), Support Vector Machines (SVM), Susceptible-Exposed-Infectious-Recovered (SEIR) models, Geographic Information Systems (GIS), Species Distribution Models (SDMs), Agricultural Production Systems sIMulator (APSIM), and Integrated Pest Management (IPM). Crucial strategies encompass integrated pest and disease management, adaptive breeding, precision agriculture, and ongoing innovation. Precision agriculture technologies, such as remote sensing and drones, enable early detection and prompt interventions. By adopting these adaptive measures and addressing existing research gaps, the sugarcane industry can bolster its resilience and maintain productivity amidst evolving climatic conditions.Systematic review registrationhttps://www.bmj.com/content/372/bmj.n71.
Evaluating plantar biomechanics while descending a single step with different heights
Authors: Guo Panjing , Zhang Xiajing , Xu Haoran , Wang Ruiqin , Li Yumin , Xu Chengshuo , Yang Yu , Zhang Linlin , Adams Roger , Han Jia , Lyu Jie 
Published: August 2024

ObjectiveThis study aims to investigate the plantar biomechanics of healthy young males as they descend a single transition step from varying heights.MethodsThirty healthy young males participated the experiment using the F-scan insole plantar pressure system in which participants made single transition steps descent from four step heights (5, 15, 25, and 35 cm), leading with their dominant or non-dominant foot. Plantar pressure data were collected for 5 s during the period between landing touchdown and standing on the ground. Landing at each step height was repeated three times, with a five-minute rest between different height trials.ResultsAt 5 cm and 15 cm steps, participants demonstrated a rearfoot landing strategy on both sides. However, forefoot contact was observed at heights of 25 cm and 35 cm. Parameters related to center of plantar pressure (COP) of the leading foot were significantly larger compared to the trailing foot (P &lt; 0.001), increased with higher step heights. Vertical ground reaction forces for the biped, leading and trailing feet decreased with increasing step height (all P &lt; 0.05). The leading foot had a higher proportion of overall and forefoot loads, and a lower proportion of rearfoot load compared to the trailing foot (P &lt; 0.001). The overall load on the dominant side was lower than that on the non-dominant side for both the leading and trailing feet (P &lt; 0.001). For the trailing foot, forefoot load on the dominant side was lower than that on the non-dominant side, however, the opposite result appeared in rearfoot load (P &lt; 0.001). Upon the leading foot landing, forefoot load exceeded the rearfoot load for the dominant (P &lt; 0.001) and non-dominant sides (P &lt; 0.001). Upon the trailing foot landing, forefoot load was lower than the rearfoot load for the dominant (P &lt; 0.001) and non-dominant sides (P = 0.019).ConclusionWhen the characteristics of biomechanical stability are compromised by step height, landing foot, and footedness factors — due to altered foot landing strategies, changing COP, or uneven force distribution — ability to control motion efficiently and respond adaptively to the forces experienced during movement is challenged, increasing the likelihood of loss of dynamic balance, with a consequent increased risk of ankle sprains and falls.
Prolonged sitting reduces cerebral oxygenation in physically active young adults
Authors: Baker Brett D. , Castelli Darla M. 
Published: August 2024

IntroductionPhysical activity is known to enhance cognitive functioning across the lifespan, yet the effects of sedentary behaviors on cognitive functioning remain unclear. The purpose of this study was to determine how an acute daily bout of prolonged sitting influenced working memory, inhibitory control, and cerebral oxygenation (HbO2) in a sample of healthy young adults.MethodsForty-one young adults (aged between 18–30 years of age) participated in an exploratory design intended to establish a control standard for determining how an acute 2-h bout of prolonged sitting influenced working memory, inhibitory control, and HbO2. The Flanker task, Simon task, and Delayed Match to Sample were utilized to assess inhibitory control and working memory, respectively, while functional near-infrared spectroscopy assessed HbO2. Participants were further subdivided into a physically active (Active) group and a physically inactive group (Inactive) based on self-reported physical activity participation. Paired sample t-tests were used to determine any changes in working memory, inhibitory control, and HbO2 from pre-to-post and between groups.ResultsThere were no differences in working memory or inhibitory control reaction time following prolonged sitting for the entire sample (p &gt; 0.05) or between activity groups (p &gt; 0.05). There was a significant reduction in Flanker accuracy post-prolonged sitting for both the congruent (p &lt; 0.05) and incongruent (p &lt; 0.05) conditions. For those in the Inactive group, there was no difference in HbO2 concentrations post-prolonged sitting. Those in the Active group exhibited a significant reduction in HbO2 during the Flanker Task following prolonged sitting (p &lt; 0.05).ConclusionsAn acute bout of daily prolonged sitting significantly reduced HbO2 in physically active young adults but not in inactive young adults. We recommend that future studies examining the effects of sedentary behaviors on microvasculature include an objective assessment of physical fitness and a direct measure of physical activity patterns and consider these values when assigning participants to the intervention condition.