bluuebunny/crossref_metadata_2025_split huggingface dataset:
CEO transformational leadership and top manager ambidexterity
Authors: Li Ci-Rong , Lin Chen-Ju , Tien Yun-Hsiang 
Published: October 2015

Purpose– The purpose of this paper is to explore the role of CEO transformational leadership in promoting ambidexterity of top managers. This paper posits that connecting CEO transformational leadership with the CEO-top manager interface offers a better explanation of heterogeneity in top manager ambidextrous behavior.Design/methodology/approach– This study is based on a questionnaire survey of 388 senior managers in 80 top teams nested in 80 small- to medium-sized Taiwan manufacturing firms.Findings– The findings indicate that transformational CEOs shape the CEO-top manager interface, characterized by senior team behavioral integration, decentralization of responsibilities, long-term compensation, and individual manager risk propensity, and in turn promote ambidexterity at the individual top manager level.Originality/value– Hence, the authors contribute to the existing understanding that transformational CEOs may not only have a beneficial influence on firm-level ambidexterity, but also may be particularly effective in enabling individual-level top managers to simultaneously explore and exploit.
Motivating continued knowledge sharing in crowdsourcing
Authors: Heo Misook , Toomey Natalie 
Published: October 2015

Purpose– The purpose of this paper is to investigate the impact of system-generated visual feedback and continued contribution on individuals’ motivation to share knowledge in a crowdsourcing environment.Design/methodology/approach– An experimental setting was designed to investigate participants’ motivation to contribute knowledge in a crowdsourcing environment. Responses from a total of 101 participants were analyzed. The independent variables were visual feedback and time. The dependent variable was the participants’ self-expressed willingness to further contribute in the experimental knowledge-sharing activity.Findings– A significant main effect of time was found, showing overall gains in the mean willingness to participate over time. It was also found that the mean willingness of the control and top assimilation groups were higher than the mean willingness of the rank contrast and status groups. The mean difference obtained for the control group was mainly during the first half of the knowledge-sharing tasks, while the mean difference obtained for the top assimilation group was mainly during the second half of the knowledge-sharing tasks.Originality/value– This study contributes to the literature related to motivation in knowledge sharing by providing theory-based, empirical evidence of the potential for external interventions to improve willingness to contribute and sustain knowledge sharing. The findings additionally provide practical implications for motivating and sustaining knowledge sharing.
On the capacity to suffer one's self
Authors: Mizen Richard 
Published: October 2015

AbstractProblems in the establishment of the sense of a ‘psychic’ skin, in the ways described by Bick and Meltzer for example, commonly give rise to distortions in the capacity for self‐experiences as a consequence of difficulties in relation to projective and identificatory processes. These latter may acquire a markedly adhesive character as a defence against the anxieties that arise. This makes for considerable technical difficulties in an analysis. This essay addresses the nature of these problems and considers some of the ways in which they may be approached clinically.
On the analysand's need to know the real person of the analyst
Authors: K  
Published: October 2015

AbstractBut the conscious achievement of inner unity clings to human relationships as to an indispensable condition. C.G.Jung (1946, p.233)Based on personal experience the main part of this paper explores the theme of the analysand's need to know the real person of the analyst and the importance, on occasion, of the analyst's disclosure of subjectivity. The concluding part offers suggestions about working with analysands where there is early emotional damage and deficits in relationship.
Synchronicity, the infinite unrepressed, dissociation and the interpersonal
Authors: Carvalho Richard 
Published: October 2015

AbstractThis paper uses the logic derived by Matte Blanco to provide an Archimedean point and a mathematics, both of which Jung complained of lacking, with which to validate the notion of synchronicity and to demonstrate that it is one of the inevitable properties of an unconscious which is unrepressed such as Jung's collective unconscious, and that such an unconscious will also be affective and interpersonal as well as intrapersonal. These have important clinical implications. After an exposition of Matte Blanco's thinking, some clinical material is presented of an episode in which patient and author both suffered the same psychosomatic symptom some time just prior to a session. Correspondences between Matte Blanco's logically derived ideas and Jung's phenomenological observations are made.
Does Medicaid Managed Care Help Equalize Racial and Ethnic Disparities in Utilization?
Authors: Marton James , Yelowitz Aaron , Shores Meredith , Talbert Jeffery C. 
Published: October 2015

ObjectiveTo estimate the impact of different forms of Medicaid managed care (MMC) delivery on racial and ethnic disparities in utilization.Data SourceLongitudinal, administrative data on 101,649 children in Kentucky continuously enrolled in Medicaid between January 1997 and June 1999. Outcomes considered are monthly professional, outpatient, and inpatient utilization.Study DesignWe apply an intent‐to‐treat, instrumental variables analysis using the staggered geographic implementation of MMC to create treatment and control groups of children.Principal FindingsThe implementation of MMC reduced monthly professional visits by a smaller degree for non‐whites than whites (3.8 percentage points vs. 6.2 percentage points), thereby helping to equalize the initial racial/ethnic disparity in utilization. The Passport MMC program in the Louisville‐centered region statistically significantly reduced disparities for professional visits (closing the gap by 8.0 percentage points), while the Kentucky Health Select MMC program in the Lexington‐centered region did not. No substantive impact on disparities was found for either outpatient or inpatient utilization in either program.ConclusionsWe find evidence that MMC has the possibility to reduce racial/ethnic disparities in professional utilization. More work is needed to determine which managed care program characteristics drive this result.
Low Glucose Degradation Product Peritoneal Dialysis Regimen Is Associated With Lower Plasma EN‐RAGE and HMGB‐1 Proinflammatory Ligands of Receptor for Advanced Glycation End Products
Authors: Opatrna Sylvie , Popperlova Anna , Kalousová Marta , Zima Tomas 
Published: October 2015

AbstractIntraperitoneal glucose degradation products (GDP) load influences systemic advanced glycation end products (AGEs) but the effects on soluble receptor for AGEs (s‐RAGE) and its proinflammatory ligands: extracellular newly identified receptor for advanced glycation end‐products binding protein(EN‐RAGE) and high mobility group box‐1 protein (HMGB‐1) are unknown. We aimed to compare plasma and peritoneal s‐RAGE, EN‐RAGE and HMGB‐1 between three peritoneal dialysis (PD) prescription regimens with different intraperitoneal GDP loads. High GDP load (glucose‐lactate PD fluid, D; N = 8) was compared with a low (glucose‐bicarbonate/lactate with icodextrin for overnight dwell, E; N = 9) and a very low GDP load (glucose‐bicarbonate/lactate, P; N = 16). D group demonstrated higher plasma EN‐RAGE, 77.8 ng/mL, vs. both E, 11.2, P < 0.001 and P, 27.0, P < 0.001 as well as higher plasma HMGB‐1, 2.2 ng/mL vs. both E, 1.1, P < 0.01 and P, 1.5, P < 0.01. Plasma s‐RAGE, which did not differ between D, E and P, correlated with its effluent levels. Patients with faster peritoneal transport (D/Pcr > 0.65) tended to have higher plasma s‐RAGE compared to slow transporters (2300 vs. 1762 pg/mL, P = 0.056). Peritoneal clearance of s‐RAGE and EN‐RAGE was higher with E compared to both D and P (P < 0.001 resp. P < 0.01). Subgroup of PD patients with CRP above median demonstrated higher plasma HMGB‐1 and EN‐RAGE, P < 0.05 for both. A lower intraperitoneal GDP load is associated with decreased plasma levels of EN‐RAGE and HMGB‐1. Peritoneal transport, microinflammation and the capability of icodextrin to increase peritoneal clearance of middle molecular weight substances might also exert an effect on plasma s‐RAGE and its proinflammatory ligands levels.
Effective Combination Therapy of Polymyxin‐B Direct Hemoperfusion and Recombinant Thrombomodulin for Septic Shock Accompanied by Disseminated Intravascular Coagulation: A Historical Controlled Trial
Authors: Yamato Masafumi , Minematsu Yusuke , Fujii Junya , Mori Kohei , Minato Takumi , Miyagawa Sachie , Fujimura Ryuta , Morikage Naoko , Arata Yuka , Nakano Chisako , Wada Akira , Ito Takahito 
Published: October 2015

AbstractDisseminated intravascular coagulation (DIC) and multiple organ failure often occur via the crosstalk between inflammation and coagulation, which is mediated by High Mobility Group Box 1 (HMGB1). In septic shock, Polymyxin‐B direct hemoperfusion (PMX‐DHP) ameliorates hemodynamics by endogenous cannabinoid adsorption and improves pulmonary oxygenation by indirect cytokine reduction through the adsorption of activated mononuclear cells. However, PMX‐DHP has no direct effect on HMGB1 circulating in the plasma. In cases with DIC, recombinant thrombomodulin (rTM), an effective drug for DIC, exerts not only anticoagulation but also antiinflammatory properties via direct anti‐HMGB1 activity. Therefore, a combination of PMX‐DHP and rTM is expected to block the vicious cycle of a cytokine storm ending up with multiple organ failure in DIC. The aim of this study was to investigate the efficacy of combination therapy for septic shock associated with DIC. This study comprised 22 consecutive patients with sepsis‐induced DIC who received PMX‐DHP. The initial eight patients were treated without rTM (historical control group), and the following 14 patients were given rTM (rTM group). The baseline Sequential Organ Failure Assessment (SOFA) score or age was not different between both groups. Sixty‐day survival rate in the rTM group was significantly higher than that in the control group (85.7% vs. 37.5%, P = 0.015). A combination of PMX‐DHP and rTM may be effective in septic shock accompanied by DIC and is expected to improve survival rates.
Analysis of Protein Removal Properties During Cryofiltration Apheresis Using the Evaflux‐5A Plasma Fractionator in a Patient With Hepatitis C Virus‐Associated Cryoglobulinemic Glomerulonephritis
Authors: Nakajima Hirofumi , Kaneko Shuzo , Takano Tomoo , Hoshino Toshihisa , Sato Yukihiro , Kawase Tomonori , Tsukamoto Yusuke 
Published: October 2015

AbstractCryofiltration (CF) is a technique in which separated plasma is chilled before being subjected to a plasma fractionator (PF), leading to cryoglobulin precipitation or cryogel formation. In CF using the Evaflux‐5A as the PF, there is no consensus on the necessity of albumin supplementation, and when or how often the PF column should be washed. We analyzed the sieving effects of various solutes (albumin, IgG, IgM, LDL, HCV‐RNA, and cryoglobulin) depending on transmembrane pressure (TMPPF) during CF using the Evaflux‐5A in a patient with hepatitis C virus‐associated cryoglobulinemic glomerulonephritis. Five CF treatments were initially performed and a sixth one later, at disease recurrence. Quantitative detection of cryoglobulin and a marked rise in TMPPF to 400 mm Hg were observed only at the first and sixth treatment, and albumin losses during these treatments were very high, at 16.8 g, and 14.6 g, respectively, while those of others (from the second to fifth) were 6.7 g, 6.4 g, 5.9 g, and 7.0 g, respectively. The sieving coefficients (SCs) of both albumin and IgG were stable (0.8–1.0) at TMPPF < 200 mm Hg, but significantly decreased at TMPPF ≥ 200 mm Hg (P < 0.01). The SC of IgM tended to decrease at TMPPF ≥ 200 mm Hg, but not significantly, while that of LDL was zero regardless of the TMPPF. Albumin loss per treatment likely depends on degree of TMPPF rise, which is mainly affected by the patient's cryoglobulinemic status. In CF using Evaflux‐5A, washing the PF column to keep TMPPF < 200 mm Hg during treatment may be a recommended for selective removal and albumin salvage.
Whither Geography? A Response to Finlayson's Concerns
Authors: Holmes John 
Published: October 2015

AbstractPrompted by Brian Finlayson's editorial, titled ‘Whither (or Wither?) Geography’, I am reminded that a review of the discipline's status and directions would be timely, using the 2002 Australia‐wide reviews in this journal as benchmarks. I welcome the thoughtful proposal for a disciplinary report to the Academy of Science recently prepared by Alaric Maude on behalf of the National Committee for Geography. I take the view that the three central issues are: firstly, flux in the discipline's ‘external relations’ in an era of interdisciplinarity, cross‐disciplinary mergers, instrumentalism, and budgetary constraints; secondly, flux in ‘internal relations’ involving subdisciplines and subcultures: and thirdly, flux in ‘vertical relations’ involving the links between secondary and tertiary Geography. It is instructive to note that the earliest disciplinary reviews, up to the 1980s, were solely directed towards bibliographic celebrations of research directions whereas recent reviews, of necessity, have been focussed on pressing issues concerning ‘Whither Geography?’. Alaric's proposal will also be issue focussed, with its emphasis on relevance and on contributions of national significance.
Modernizing wholesalers and guava farmers in Mexico
Authors: Hernandez Ricardo , Berdegué Julio A. , Reardon Thomas 
Published: October 2015

AbstractThis article focuses on the rapid development of the “modernizing wholesale” channel, with a study of guava traders and farmers in Mexico. This adds to a literature on modernization of food markets that has focused primarily on exports, supermarkets, and large processors and addressed less wholesale in general and rarely modernizing wholesale per se. We find that participation in the modernizing wholesale channel, relative to the traditional broker channel, requires greater land, regional, and nonland assets, as well as confers a premium controlling for quality, and spurs employment in harvesting and handling locally.
Recombinant tissue plasminogen activator (rt‐PA) utilisation by rural clinicians in acute ischaemic stroke: A survey of barriers and enablers
Authors: Williams Jocelyn M. , Jude Martin R. , Levi Christopher R. 
Published: October 2015

AbstractObjectiveThis paper identified barriers which prevent rural health care providers from utilising rt‐PA in acute ischaemic stroke and proposes possible support mechanisms to increase its utilisation.MethodsThis descriptive study uses data from anonymous surveys distributed to health care providers involved in acute stroke patient care in three rural hospitals with rt‐PA pathways. Saturation sampling was used. Surveys gathered self assessed ratings of experience, practice environment, attitudes, existing support, barriers and possible enablers regarding rt‐PA use in acute stroke.ResultsPhysicians reported the strongest barriers to the use of rt‐PA in acute stroke as pre‐hospital delays (91%), risk of intracerebral haemorrhage (ICH) (73%) and clinical diagnostic uncertainty (60%). They reported high levels of confidence in the support received from their stroke units (90%). Nurses identified a poor level of stroke education and knowledge on rt‐PA utilisation in acute stroke. A third of nurses could correctly list six different stroke signs. The risk of ICH following rt‐PA administration in stroke was also a significant barrier for nurses. Response rate from physicians was 26% (10/38) and 19% (13/69) for nurses.ConclusionsTo reduce barriers to rt‐PA utilisation in rural facilities physicians require education on the calculated risk of ICH as well as exposure and experience to improve their ability to confidently diagnose stroke patients who are eligible for rt‐PA treatment. Education for nurses on symptoms of stroke and rt‐PA utilisation and administration is recommended.
Intra‐abdominal blockage of a ventriculoperitoneal shunt by a suspected mesenteric pseudocyst in a dog
Authors: Driver CJ , Pinilla MJ , Loderstedt S , Kenny PJ 
Published: October 2015

BackgroundThere are few reports of abdominal complications following ventriculoperitoneal (VP) shunt placement for the treatment of hydrocephalus in dogs.Case reportA 3‐year‐old dog underwent successful VP shunting for the treatment of hydrocephalus, but re‐presented 10 months later with progressive central vestibular syndrome. Magnetic resonance imaging of the brain suggested VP catheter obstruction. The dog was euthanased and on postmortem examination the abdominal tip of the VP catheter was ensheathed and blocked by fibrous mesentery, possibly a pseudocyst.ConclusionsAbdominal complications are common in humans, with pseudocysts reported in up to 4.5% of cases. This diagnosis should be considered for dogs re‐presenting following VP shunt surgery.
Triggering of Suicidal Erythrocyte Death by the Antibiotic Ionophore Nigericin
Authors: Bissinger Rosi , Malik Abaid , Bouguerra Ghada , Zhou Yuetao , Singh Yogesh , Abbès Salem , Lang Florian 
Published: October 2015

AbstractThe K+,H+ ionophore and antibiotic nigericin has been shown to trigger apoptosis and is thus considered for the treatment of malignancy. Cellular mechanisms involved include induction of oxidative stress, which is known to activate erythrocytic Ca2+‐permeable unselective cation channels leading to Ca2+ entry, increase in cytosolic Ca2+ activity ([Ca2+]i) and subsequent stimulation of eryptosis, the suicidal erythrocyte death characterized by cell shrinkage and cell membrane scrambling with phosphatidylserine translocation to the erythrocyte surface. This study explored whether and how nigericin induces eryptosis. Phosphatidylserine exposure at the cell surface was estimated from annexin V binding, cell volume from forward scatter, [Ca2+]i from Fluo3 fluorescence, pHi from BCECF fluorescence, ceramide abundance utilizing antibodies and reactive oxygen species (ROS) formation from DCFDA‐dependent fluorescence. A 48‐hr exposure of human erythrocytes to nigericin significantly increased the percentage of annexin‐V‐binding cells (0.1–10 nM), significantly decreased forward scatter (0.1–1 nM), significantly decreased cytosolic pH (0.1–1 nM) and significantly increased Fluo3 fluorescence (0.1–10 nM). Nigericin (1 nM) slightly, but significantly, increased ROS, but did not significantly modify ceramide abundance. The effect of nigericin on annexin V binding was significantly blunted, but not abolished by removal of extracellular Ca2+. The nigericin‐induced increase in [Ca2+]i and annexin V binding was again significantly blunted but not abolished by the Na+/H+ exchanger inhibitor cariporide (10 μM). Nigericin triggers eryptosis, an effect paralleled by ROS formation, in part dependent on stimulation of Ca2+ entry, and involving the cariporide‐sensitive Na+/H+ exchanger.
An Approximate Marginal Logistic Distribution for the Analysis of Longitudinal Ordinal Data
Authors: Nooraee Nazanin , Abegaz Fentaw , Ormel Johan , Wit Ernst , van den Heuvel Edwin R 
Published: October 2015

SummarySubject-specific and marginal models have been developed for the analysis of longitudinal ordinal data. Subject-specific models often lack a population-average interpretation of the model parameters due to the conditional formulation of random intercepts and slopes. Marginal models frequently lack an underlying distribution for ordinal data, in particular when generalized estimating equations are applied. To overcome these issues, latent variable models underneath the ordinal outcomes with a multivariate logistic distribution can be applied. In this article, we extend the work of O'Brien and Dunson (2004), who studied the multivariate t-distribution with marginal logistic distributions. We use maximum likelihood, instead of a Bayesian approach, and incorporated covariates in the correlation structure, in addition to the mean model. We compared our method with GEE and demonstrated that it performs better than GEE with respect to the fixed effect parameter estimation when the latent variables have an approximately elliptical distribution, and at least as good as GEE for other types of latent variable distributions.
Physician‐Led, Hospital‐Linked, Birth Care Centers can Decrease Cesarean Section Rates Without Increasing Rates of Adverse Events
Authors: O'Hara Margaret H. , Frazier Linda M. , Stembridge Travis W. , McKay Robert S. , Mohr Sandra N. , Shalat Stuart L. 
Published: October 2015

AbstractBackgroundThis study compares outcomes at a hospital‐linked, physician‐led, birthing center to a traditional hospital labor and delivery service.MethodsUsing de‐identified electronic medical records, a retrospective cohort design was employed to evaluate 32,174 singleton births during 1998–2005.ResultsCompared with hospital service, birth care center delivery was associated with a lower rate of cesarean sections (adjusted Relative Risk = 0.73, 95% confidence interval 0.59–0.91; p < 0.001) without an increased rate of operative vaginal delivery (adjusted Relative Risk = 1.04, 95% confidence interval 0.97–1.13; p = 0.25) and a higher initiation of breastfeeding (adjusted Relative Risk = 1.28, 95% confidence interval 1.25–1.30; p ≤ 0.001). A maternal length of stay greater than 72 hours occurred less frequently in the birth care center (adjusted Relative Risk = 0.60, 95% confidence interval 0.55–0.66; p < 0.001). Comparing only women without major obstetrical risk factors, the differences in outcomes were reduced but not eliminated. Adverse maternal and infant outcomes were not increased at the birth care center.ConclusionA hospital‐linked, physician‐led, birth care center has the potential to lower rates of cesarean sections without increasing rates of operative vaginal delivery or other adverse maternal and infant outcomes.