bluuebunny/crossref_metadata_2025_split huggingface dataset:
Developmental trends in auditory processing can provide early predictions of language acquisition in young infants
Authors: Chonchaiya Weerasak , Tardif Twila , Mai Xiaoqin , Xu Lin , Li Mingyan , Kaciroti Niko , Kileny Paul R. , Shao Jie , Lozoff Betsy 
Published: December 2012

AbstractAuditory processing capabilities at the subcortical level have been hypothesized to impact an individual's development of both language and reading abilities. The present study examined whether auditory processing capabilities relate to language development in healthy 9‐month‐old infants. Participants were 71 infants (31 boys and 40 girls) with both Auditory Brainstem Response (ABR) and language assessments. At 6 weeks and/or 9 months of age, the infants underwent ABR testing using both a standard hearing screening protocol with 30 dB clicks and a second protocol using click pairs separated by 8, 16, and 64‐ms intervals presented at 80 dB. We evaluated the effects of interval duration on ABR latency and amplitude elicited by the second click. At 9 months, language development was assessed via parent report on the Chinese Communicative Development Inventory ‐ Putonghua version (CCDI‐P). Wave V latency z‐scores of the 64‐ms condition at 6 weeks showed strong direct relationships with Wave V latency in the same condition at 9 months. More importantly, shorter Wave V latencies at 9 months showed strong relationships with the CCDI‐P composite consisting of phrases understood, gestures, and words produced. Likewise, infants who had greater decreases in Wave V latencies from 6 weeks to 9 months had higher CCDI‐P composite scores. Females had higher language development scores and shorter Wave V latencies at both ages than males. Interestingly, when the ABR Wave V latencies at both ages were taken into account, the direct effects of gender on language disappeared. In conclusion, these results support the importance of low‐level auditory processing capabilities for early language acquisition in a population of typically developing young infants. Moreover, the auditory brainstem response in this paradigm shows promise as an electrophysiological marker to predict individual differences in language development in young children.
ANS acuity and mathematics ability in preschoolers from low‐income homes: contributions of inhibitory control
Authors: Fuhs Mary Wagner , McNeil Nicole M. 
Published: December 2012

AbstractRecent findings by Libertus, Feigenson, and Halberda (2011) suggest that there is an association between the acuity of young children's approximate number system (ANS) and their mathematics ability before exposure to instruction in formal schooling. The present study examined the generalizability and validity of these findings in a sample of preschoolers from low‐income homes. Children attending Head Start (N = 103) completed measures to assess ANS acuity, mathematics ability, receptive vocabulary, and inhibitory control. Results showed only a weak association between ANS acuity and mathematics ability that was reduced to non‐significance when controlling for a direct measure of receptive vocabulary. Results also revealed that inhibitory control plays an important role in the relation between ANS acuity and mathematics ability. Specifically, ANS acuity accounted for significant variance in mathematics ability over and above receptive vocabulary, but only for ANS acuity trials in which surface area conflicted with numerosity. Moreover, this association became non‐significant when controlling for inhibitory control. These results suggest that early mathematical experiences prior to formal schooling may influence the strength of the association between ANS acuity and mathematics ability and that inhibitory control may drive that association in young children.
Infants' mu suppression during the observation of real and mimicked goal‐directed actions
Authors: Warreyn Petra , Ruysschaert Lieselot , Wiersema Jan R. , Handl Andrea , Pattyn Griet , Roeyers Herbert 
Published: December 2012

AbstractSince their discovery in the early 1990s, mirror neurons have been proposed to be related to many social‐communicative abilities, such as imitation. However, research into the early manifestations of the putative neural mirroring system and its role in early social development is still inconclusive. In the current EEG study, mu suppression, generally thought to reflect activity in neural mirroring systems was investigated in 18‐ to 30‐month‐olds during the observation of object manipulations as well as mimicked actions. EEG power data recorded from frontal, central, and parietal electrodes were analysed. As predicted, based on previous research, mu wave suppression was found over central electrodes during action observation and execution. In addition, a similar suppression was found during the observation of intransitive, mimicked hand movements. To a lesser extent, the results also showed mu suppression at parietal electrode sites, over all three conditions. Mu wave suppression during the observation of hand movements and during the execution of actions was significantly correlated with quality of imitation, but not with age or language level.
Frontolimbic neural circuitry at 6 months predicts individual differences in joint attention at 9 months
Authors: Elison Jed T. , Wolff Jason J. , Heimer Debra C. , Paterson Sarah J. , Gu Hongbin , Hazlett Heather C. , Styner Martin , Gerig Guido , Piven Joseph ,   for the IBIS Network
Published: December 2012

AbstractElucidating the neural basis of joint attention in infancy promises to yield important insights into the development of language and social cognition, and directly informs developmental models of autism. We describe a new method for evaluating responding to joint attention performance in infancy that highlights the 9‐ to 10‐month period as a time interval of maximal individual differences. We then demonstrate that fractional anisotropy in the right uncinate fasciculus, a white matter fiber bundle connecting the amygdala to the ventral‐medial prefrontal cortex and anterior temporal pole, measured in 6‐month‐olds predicts individual differences in responding to joint attention at 9 months of age. The white matter microstructure of the right uncinate was not related to receptive language ability at 9 months. These findings suggest that the development of core nonverbal social communication skills in infancy is largely supported by preceding developments within right lateralized frontotemporal brain systems.
Ethical Issues in Field Trials of Genetically Modified Disease‐Resistant Mosquitoes
Authors: Resnik David B. 
Published: December 2012

AbstractMosquito‐borne diseases take a tremendous toll on human populations, especially in developing nations. In the last decade, scientists have developed mosquitoes that have been genetically modified to prevent transmission of mosquito‐borne diseases, and field trials have been conducted. Some mosquitoes have been rendered infertile, some have been equipped with a vaccine they transmit to humans, and some have been designed to resist diseases. This article focuses on ethical issues raised by field trials of disease‐resistant, genetically modified mosquitoes. Some of these issues include: protecting the public and the environment from harm, balancing benefits and risks, collaborating with the local community, avoiding exploitation, and safeguarding the rights and welfare of research subjects. One of the most difficult problems involves protecting the welfare of community members who will be impacted by the release of mosquitoes but who are not enrolled in the study as research subjects. To address this concern, field trials should take place only when the targeted disease is a significant public health problem in an isolated area, the benefits of the trial for the community are likely to outweigh the risks, community leaders approve of the trial, and there are measures in place to protect the welfare of un‐enrolled community members, such as informing the community about the study and offering free treatment to people who contract mosquito‐borne diseases. Since the justification of any field trial depends on a careful examination of the scientific and ethical issues, proposed studies should be evaluated on a case‐by‐case basis.
Alternatives of Informed Consent for Storage and Use of Human Biological Material for Research Purposes: Brazilian Regulation
Authors: Marodin Gabriela , França Paulo Henrique Condeixa de , Salgueiro Jennifer Braathen , Motta Marcia Luz da , Tannous Gysélle Saddi , Lopes Anibal Gil 
Published: December 2012

AbstractInformed consent is recognized as a primary ethical requirement to conduct research involving humans. In the investigations with the use of human biological material, informed consent (IC) assumes a differentiated condition on account of the many future possibilities. This work presents suitable alternatives for IC regarding the storage and use of human biological material in research, according to new Brazilian regulations. Both norms – Resolution 441/11 of the National Health Council, approved on 12 May 2011, and Ordinance 2.201 (NATIONAL GUIDELINES FOR BIOREPOSITORIES AND BIOBANKS OF HUMAN BIOLOGICAL MATERIAL FOR RESEARCH PURPOSE) of the Brazil Ministry of Health, approved on 14 September 2011 – state that the consent of subjects for the collection, storage and use of samples stored in Biobanks is necessarily established by means of a Free and Informed Consent Form (ICF). In order to obtain individual and formal statements, this form should contain the following two mutually exclusive options: an explanation about the use of the stored material in each research study, and the need for new consent or the waiver thereof when the material is used for a new study. On the other hand, ICF suitable for Biorepositories must be exclusive and related to specific research. Although Brazilian and international regulations identify the main aspects to be included in the IC, efforts are still necessary to improve the consent process, so that the document will become a bond of trust between subject and researcher.
The aftermath of reunification
Authors: Kohn Karsten , Antonczyk Dirk 
Published: December 2012

AbstractThis article traces the evolution of the East German wage structure throughout the transition period 1992–2001. Wage dispersion has generally been rising. This increase occurred predominantly in the lower part of the wage distribution for women and in the upper part for men. Moreover, the sectoral transition affected female workers to a much larger extent than their male counterparts. A sequential decomposition analysis using quantile regressions reveals that changes in industry‐specific remuneration schemes contributed strongly to the rise in wage inequality in the lower part of the distribution for women, whereas changes in the industry composition alone would have led to a polarization of wages. In contrast, for men, changes in individual characteristics are the single most important factor contributing to the increasing wage dispersion. These gender differences are attributed to employment segregation across industries present right after German reunification.
The end of economic transition
Authors: Sonin Konstantin 
Published: December 2012

AbstractThe transition from plan to market was the largest natural experiment in economics ever. Now, 20 years from the start of transition, all former socialist countries are market economies at the middle stage of economic development, and convergence with neighbours, if not with the developed world, is largely achieved. With hindsight, it is clear that economists have spent too much time debating proper sequencing of reforms and the fine‐tuning of reform packages. At the same time, the magnitude of the output and consumption fall in some countries was vastly underestimated, while the benefits of reforms have taken longer to materialize than expected. Successful practitioners of reform praise perseverance during and after the initial setbacks and willingness to make political compromises. At the conclusion of the natural experiment, transition economics has all but vanished as an academic discipline, although it played a crucial role in the formation of modern political economics.
‘Le Crete 1’ and ‘Le Crete 2’: two newly patentedSeiridium cardinalecanker‐resistant cultivars ofCupressus sempervirens
Authors: Danti R. , Di Lonardo V. , Pecchioli A. , Della Rocca G. 
Published: December 2012

SummaryIn the Mediterranean area, common cypress (Cupressus sempervirens) has traditionally been used as a multipurpose tree, for its symbolic and ornamental role, for its valuable timber, as well as for windbreaks and soil protection. The epidemic spread of theSeiridium cardinalecanker has limited the use of this tree since the 1970s, inducing researchers to develop a breeding programme of cypress aimed at selecting canker‐resistant lines for different uses and to support a flourishing trade of cypress plants. ‘Le Crete 1’ and ‘Le Crete 2’ described here are two new canker‐resistantC. sempervirensvarieties patented in 2010, selected through a 13‐year assessment of their response to artificial inoculations and growth traits. Both are characterized by a rapid growth and by a columnar and fastigiated habit that confers them a notable ornamental effect. Preliminary observations showed also that both tend to produce yearly few microsporophylls and little pollen. ‘Le Crete 2’ was also selected for the high growth rate it maintained on heavy, clayey soils.
Separate amygdala subregions signal surprise and predictiveness during associative fear learning in humans
Authors: Boll Sabrina , Gamer Matthias , Gluth Sebastian , Finsterbusch Jürgen , Büchel Christian 
Published: December 2012

AbstractIt has recently been suggested that learning signals in the amygdala might be best characterized by attentional theories of associative learning [such as Pearce–Hall (PH)] and more recent hybrid variants that combine Rescorla–Wagner and PH learning models. In these models, unsigned prediction errors (PEs) determine the associability of a cue, which is used in turn to control learning of outcome expectations dynamically and reflects a function of the reliability of prior outcome predictions. Here, we employed an aversive Pavlovian reversal‐learning task to investigate computational signals derived from such a hybrid model. Unlike previous accounts, our paradigm allowed for the separate assessment of associability at the time of cue presentation and PEs at the time of outcome. We combined this approach with high‐resolution functional magnetic resonance imaging to understand how different subregions of the human amygdala contribute to associative learning. Signal changes in the corticomedial amygdala and in the midbrain represented unsigned PEs at the time of outcome showing increased responses irrespective of whether a shock was unexpectedly administered or omitted. In contrast, activity in basolateral amygdala regions correlated negatively with associability at the time of cue presentation. Thus, whereas the corticomedial amygdala and the midbrain reflected immediate surprise, the basolateral amygdala represented predictiveness and displayed increased responses when outcome predictions became more reliable. These results extend previous findings on PH‐like mechanisms in the amygdala and provide unique insights into human amygdala circuits during associative learning.
Cuticular hydrocarbons as a basis for chemosensory self‐referencing in crickets: a potentially universal mechanism facilitating polyandry in insects
Authors: Weddle Carie B. , Steiger Sandra , Hamaker Christopher G. , Ower Geoffrey D. , Mitchell Christopher , Sakaluk Scott K. , Hunt John 
Published: December 2012

AbstractFemales of many species obtain benefits by mating polyandrously, and often prefer novel males over previous mates. However, how do females recognise previous mates, particularly in the face of cognitive constraints? Female crickets appear to have evolved a simple but effective solution: females imbue males with their own cuticular hydrocarbons (CHCs) at mating and utilise chemosensory self‐referencing to recognise recent mates. Female CHC profiles exhibited significant additive genetic variation, demonstrating that genetically unique chemical cues are available to support chemosensory self‐referencing. CHC profiles of males became more similar to those of females after mating, indicating physical transfer of CHCs between individuals during copulation. Experimental perfuming of males with female CHCs resulted in a female aversion to males bearing chemical cues similar to their own. Chemosensory self‐referencing, therefore, could be a widespread mechanism by which females increase the diversity of their mating partners.
Oral health‐care utilization in adults with disabilities in Belgium
Authors: Leroy Roos , Declerck Dominique 
Published: December 2012

Leroy R, Declerck D. Oral health‐care utilization in adults with disabilities in Belgium.   Eur J Oral Sci 2013; 121: 36–42. © 2012 Eur J Oral SciReports on oral health‐service utilization among individuals with disabilities are very sparse. Nevertheless, such data are a prerequisite for the provision of proper care and for the development of optimal reimbursement schemes and may ultimately lead to better access to care. The objective of the present study was to provide data on oral health‐care utilization in Belgian residents with disabilities and to compare these data with the utilization pattern of their peers without special needs. Data from the Permanent Sample of Socially Insured Persons, an anonymous representative sample of Belgian residents, were used. The database contained prospective data on oral and general health‐care utilization and socio‐demographic variables from 1,221 individuals with disabilities and from 131,877 individuals without disabilities, collected from 2002 to 2008. Overall, annual dental‐attendance rates were very low and in those who attended, professional debridements, a cornerstone in preventive oral health care, were infrequently recorded. In adults with disabilities, significantly fewer radiographs, restorations, and endodontic treatments were recorded, whereas significantly more emergency visits were charged. Further research is indicated to evaluate whether this outcome points to high unmet oral‐treatment needs.
Delegated and Implementing Rule Making: Proceduralisation and Constitutional Design
Authors: Mendes Joana 
Published: December 2012

AbstractThe reform of non‐legislative acts introduced by Articles 290 and 291 of the Treaty on the Functioning of the European Union was guided by concerns regarding the democratic legitimacy of (lato sensu) implementing acts of the Union. However, it has ignored the centrality of transparency in the Union's democracy and the role of participation as a complementary source of democracy. This article argues that the procedures leading to the adoption of delegated and implementing acts are subject to the treaties' provisions on transparency and participation, and should be shaped by them. It analyses the constitutional choices underlying Articles 290 and 291, with a view to assessing whether and to what extent the material, organic and functional profiles of delegated and implementing acts condition procedural rules on transparency and participation to be followed in their adoption.
Non‐Legislative Rule Making after the Lisbon Treaty: Implementing the New System of Comitology and Delegated Acts
Authors: Christiansen Thomas , Dobbels Mathias 
Published: December 2012

AbstractThe reform of comitology and the introduction of the new instrument of delegated acts in the Lisbon Treaty were followed by protracted negotiations on the implementation of both articles. This article examines the resultant system that has emerged for both types of non‐legislative instruments. In the area of implementing acts, a new regulation sets out important changes: a reduction in the number of procedures, the extension of the scope to trade defence measures and the replacement of a referral to the Council with a new appeal committee. With respect to delegated acts, the search for an overarching framework resulted in a Common Understanding. Our analysis not only demonstrates the need to go beyond the treaty provisions in understanding the nature of non‐legislative rule making in the EU, but also emphasises the importance of informal procedures and non‐binding agreements in fully assessing the nature of non‐legislative rule making in this area.
European Agencies' Rulemaking: Powers, Procedures and Assessment
Authors: Chiti Edoardo 
Published: December 2012

AbstractThis article aims at identifying European agencies' rulemaking powers, mapping the procedures through which such powers are exercised and assessing the existing procedural arrangements. The first section analyses the main forms of European agencies' rulemaking. It shows, on the one hand, that not all European agencies are actually engaged in the adoption of administrative rules, on the other hand, that European agencies carrying out rulemaking activities tend to converge on two specific forms of rulemaking, namely participation in the adoption of binding implementing rules and regulation by soft law. The second section, devoted to mapping the procedures through which rulemaking powers are exercised, argues that the two main types of European agencies' rulemaking cannot be said to be subject to a really common procedural framework. In both cases, the emerging procedural rules implement the same principles of transparency and participation and rely on the same consultation mechanism, sometimes complemented by regulatory impact assessment. Yet, proceduralisation has an uneven development: while the establishment of a procedural discipline is quite common with reference to participation in the adoption of binding implementing rules, regulation by soft law remains largely under‐proceduralised. The last section proposes an assessment of the European agencies' rulemaking procedures. Two main shortcomings are identified: the asymmetry between the tendency to proceduralise the adoption of binding implementing rules and the parallel tendency to keep informal the process of adoption of soft law measures; and the too rudimental development of consultation.
Rule‐Making by the European Financial Supervisory Authorities: Walking a Tight Rope
Authors: Busuioc Madalina 
Published: December 2012

AbstractThe new European Financial Supervisory Authorities have received much attention in the literature, particularly due to their exceptional emergency decision‐making powers. By contrast, this article explicitly chooses to focus on these agencies' less explored yet equally crucial role: their (quasi‐)rule‐making responsibilities. While being less striking at first sight than their emergency counterparts, these rule‐making powers are considerable, carry significant consequences, and raise some interesting dilemmas and concerns. This article complements the previous contribution by going at a lower level of specification and zooming in on a crucial case for studying rule‐making by agencies as the Authorities constitute a culmination of agency rule‐making powers, as well as agency powers, more broadly. The article will analyse the Authorities' main (quasi‐)rule‐making powers and the relevant procedures. It will specifically investigate their role with respect to the adoption of regulatory and implementing technical standards, as well as guidelines and recommendations. The article also identifies and highlights a set of problematic issues that arise, threatening to jeopardise the legitimacy and credibility of their rule‐making.