bluuebunny/crossref_metadata_2025_split huggingface dataset:
BURNOUT IN THE HYBRID WORKPLACE: EXAMINING THE STRUGGLE OF LANGUAGE LECTURERS IN MALAYSIA
Authors: Azizan Mazlin , Shafie Hidayu , Mohd Jaafar Nurjanah , Komarudin Nabila Eizati , Samud Nurul Nadia 
Published: July 2024

Background and Purpose: Many workers struggle with stressful conditions, resulting in work burnout. While studies have examined issues revolving around working from home, research on hybrid work environment is lacking, particularly in Malaysian contexts. This study aims to examine work burnout issues faced by language lecturers in a hybrid work landscape.

Methodology: A quantitative cross-sectional survey design was employed in this study. An adapted Copenhagen Burnout Inventory was administered online to 130 language lecturers from two public universities in Selangor through random sampling procedure. To determine levels of personal, work-related, and colleague-related burnout, data were analysed using descriptive statistics analyses which were conducted on SPSS Version 29.

Findings: The findings revealed that personal and work-related burnout are perceived as sometimes contributing to burnout. Conversely, colleague-related burnout is perceived less frequently, suggesting minimal impact on burnout in interactions with colleagues. The overall low burnout levels suggest that hybrid working could be an effective arrangement for educators in the long run.
Contributions: The insights gained on work burnout among language lecturers will be particularly useful in maneuvering work effectively in academia, with the hope to address issues within the UN SDG Goal 3 where good health and well-being would be the focus.

Keywords: Work-life balance, hybrid workplace, burnout, academia, language lecturers.

Cite as: Azizan, M., Shafie, H., Mohd Jaafar, N., Komarudin, N. E., & Samud, N. N. (2024). Burnout in the hybrid workplace: Examining the struggle of language lecturers in Malaysia. Journal of Nusantara Studies, 9(2), 577-602. http://dx.doi.org/10.24200/jonus.vol9iss2pp577-602
Mastectomy in ten mares: indications, surgical technique, complications, and long-term outcome
Authors: Steiner Morgan N. , Boone Lindsey H. , Hayden Lyndsey , Schumacher Jim , Arnold Carolyn E. 
Published: July 2024

Abstract

OBJECTIVE
To describe the indications for and surgical technique of mastectomy of mares and to describe the outcome of 10 mares that underwent mastectomy in a retrospective case series.

ANIMALS
10 mares having disease of one or both mammary glands.

CLINICAL PRESENTATION
Medical records (1995 to 2022) from 2 university teaching hospitals were searched to identify mares that had undergone unilateral or bilateral mastectomy. Data regarding history, signalment, diagnostic tests, preoperative treatment, surgical procedure, and postoperative management were reviewed. Follow-up information was obtained by interviewing the owners by telephone.

RESULTS
One (n = 4 mares) or both mammary glands (6 mares) were excised for the following reasons: chronic bacterial mastitis (4), neoplasia (3), lymphangiectasia (1), pythiosis (1), and lymphoid hamartoma (1). None of the mares experienced intraoperative complications. The surgical site was closed primarily in 2 mares and left unsutured in 8 mares. Both sutured wounds developed a seroma, and 1 dehisced. The owners reported that the surgical wound, whether sutured or unsutured, was healed within 3 months. All mares returned to use for their intended purpose, but 3 mares were euthanized 2 to 4 years after surgery due to progression of disease. One mare drowned 1 year after discharge.

CLINICAL RELEVANCE
Mastectomy can be an effective treatment for mares suffering from disease of one or both mammary glands when the mare is refractory to medical treatment.
Impact of size of banks and insurance companies on their profitability in Bosnia and Herzegovina
Authors: Torlaković Anes , Proho Mahir , Hadžiahmetović-Milišić Nejra , Dedović Lejla 
Published: July 2024

Abstract
In this paper, we investigate the determinants of bank profitability by examining endogenous factors used to measure the size of a financial institution. We underscore the significance of bank employees in embodying institutional values and playing a pivotal role in sales channels, as well as the impact of technological integration on customer expectations and workforce dynamics.
Utilizing a dataset from regulatory agencies, which includes information from 47 banks and insurance companies in Bosnia and Herzegovina for the year 2021, the study explores the relationship between the independent variables which include the volume of total assets and the number of employees, and the dependent variable for profitability. By calculating Return on Equity (ROE) and employing a multiple linear regression model, the study finds that a statistically significant relation between independent variables and the dependent variable does not exist. Despite this, the research highlights the need for further investigation, particularly considering the differentiation between banks and insurance companies, the potential impact of outliers, and the broader economic context of the year studied. The findings suggest that a more refined model, possibly incorporating panel data, could provide clearer insights into the profitability determinants of financial institutions in Bosnia and Herzegovina.
TGF-Β Isoforms: TGF-β1, TGF-β2 and TGF-β3 in Ligament and Tendon Healing
Authors: Krawczak-Wójcik Katarzyna , Mazurkiewicz Anna , Petr Miroslav 
Published: July 2024

Abstract

Introduction.
Tendon and ligament injuries affect people of all ages, including professional athletes. Tumor Growth Factor β (TGF- β) isoforms play a significant role in the regeneration of tendons and ligaments, such as through the recruitment of macrophages and fibroblasts or the regulation of the formation of extracellular matrix (ECM). Although the TGF- β family regulates signalling pathways related to the healing process, excessive TGF- β activation can lead to fibrosis and the formation of scars and adhesions. This article recapped the significance of TGF- β isoforms TGF- β1, TGF- β2, and TGF- β3 in the physiological healing of injured tendons and ligaments.

Material and Methods.
A total of 1434 articles were identified using the PubMed search string (TGF-β isoforms or TGF-β1 or tgfb1 or TGF-β2 or tgfb2 or TGF-β3 or tgfb3) and (tendon or ligament). Human studies, animal models and in vitro cultures were included in the search. Forty-nine published articles were included.

Results.
Histologic evidence demonstrated greater ligament and tendon regeneration and collagen type I expression when using TGF-β1, often leading to fibrosis. TGF-β3 inhibits the TGF-β1 and TGF-β2 by switching Smad2/3 signaling to Smad7 and CREB-1 transcription factor. There was a delay in TGF-β3 level peak compared to other isoforms.

Conclusions.
All 3 TGF-β isoforms seem to play a significant role in the subsequent stages of healing. We state a hypothesis that during the initial phase of tendon and ligament healing, TGF-β1 levels need to be elevated. Further, TGF-β3 may inhibit the action of TGF-β1 and TGF-β2, which leads to the inhibition of inflammation and changes in ECM production, and consequently to a reduction in the level of scarring.
Performance Analysis in Chinese Female Club Soccer Based on Offensive and Defensive Technical-Tactical Indicators
Authors: Xing Yang , Erdmann Wlodzimierz , Chamera Tomasz 
Published: July 2024

Abstract

Introduction.
This study aimed to analyze how technical and tactical performance indicators differ by different match outcomes in women’s soccer and apply a comprehensive approach to match analysis.

Material and Methods.
The investigation analyzed many technical and tactical indicators of female club players from 28 matches in the Chinese Women’s Super League during the 2020 and 2021 seasons. These included both offensive and defensive indicators, such as goal kicks, clearances, interceptions, and more. Standard scores and T-scores were considered in illustrating the typical performance status of the team. In evaluating the technical and tactical performance indicators across various match outcomes, we applied non-parametric Kruskal-Wallis tests. This approach was taken because the data were found appropriate for the non-normal distribution, allowing the comprehensive detection of the differences across game states.

Results.
Kruskal-Wallis test-based statistical analysis showed that there is a substantial number of differences in team performance across slumped and high-performance phases within the games. The passable offensive indicators, such as shot frequency and forward passes, dropped significantly during the slump (p < 0.05). Amongst the defensive actions, there were significant increases. By contrast, in high-performance phases, offensive actions-shots and forward passes were significantly more frequent (p < 0.01), indicating dynamics in the change of the team approach according to the state of play.

Conclusions.
Our analysis showed that more offensive actions relate to a win in a match, while defensive action usually leads to a lost match. This result will offer valuable information to coaches for training and game strategies.
Physical Activity and Dietary Habits in Young Females with Varying Levels of Body Fat and Fat Distribution
Authors: Agnieszka Dmitruk , Wojciech Hołub 
Published: July 2024

Abstract

Introduction.
Physical activity and good diet are the primary determinants of body weight. The aim of the study was to compare physical activity and eating behaviours of overweight and obese females (taking into consideration their body fat distribution) with individuals with normal levels of body fat.

Material and methods.
The study included females aged 20-35. The study group consisted of 449 subjects, who were categorised into groups based on their body fat percentage: underweight, normal body fat, overweight and obese. The WHR index was computed in individuals who were overweight or obese. The assessment of physical activity levels was conducted using data obtained from the IPAQ, while eating behaviours were examined using the Dietary Habits And Nutrition Beliefs Questionnaire developed by the Polish Academy of Sciences.

Results.
Females who were overweight or obese exhibited greater values of the examined physical characteristics in comparison to individuals with normal levels of body fat. Subjects with fat tissue in the abdomen area had higher values of somatic characteristics. There were no statistically significant differences in physical activity levels between individuals with normal body fat and overweight or obese females. However, when the second group was divided into those with abdominal fatness and those with peripheral fatness, it was observed that individuals with abdominal fatness had lower levels of physical activity, including both total activity as well as vigorous and moderate activity. There were no significant differences in eating behaviours found between the groups.

Conclusions.
The amount and placement of fat tissue in young females is more closely linked to their levels of physical activity rather than their eating habits and knowledge about food and nutrition.
Individual Management of Physical Activity of Tourism and Recreation Students Through Mobile Applications
Authors: Berbeka Jadwiga 
Published: July 2024

Abstract

Introduction.
The impact of mobile applications on the physical activity of Tourism and Recreation students in Krakow has not been the subject of in-depth research so far. The aim of this study is to identify the areas of management, scope of use and motivation for using mobile applications during physical activity by students of Tourism and Recreation. The theoretical framework for motivation analysis is the Achievement Goal Theory.

Material and methods.
A quantitative approach was adopted, surveys were conducted among students of Tourism and Recreation in Krakow. The basic parameters of descriptive statistics, coefficient of variation V, and correlation coefficients were calculated.

Results.
Students of Tourism and Recreation use mobile applications while running, cycling and aerobics. The most important functionalities for students are those that support processes of controlling the performance of their physical activity. The results show that, with regard to the Achievement Goal Theory, stronger motivation comes from aspects falling into the Goal category.

Conclusions.
In the theoretical aspect, the results deepened the understanding of the processes of individual management of students’ physical activity; in the methodological aspect, they allowed the researchers to conclude that the Achievement Goal Theory is suitable for analysing the motivation to use mobile applications during physical activity, while in the practical aspect, the results indicated the possibility of improving the quality of students’ physical activity through individual management with the efficient use of mobile applications.
Correlations of high miRNA expressions with traditional proteins and prognosis of breast cancer
Authors: Chen Jianrong , Zhang Haiyong , Li Xiufang , Hu Mengjun 
Published: July 2024

Abstract

Background
In this study, we aimed to analyze the correlations of high expressions of micro ribonucleic acids (miRNAs) with traditional proteins and prognosis of breast cancer.

Methods
The clinical data of 60 breast cancer patients treated from August 2018 to July 2019 were retrospectively analyzed. All the patients received radical mastectomy combined with postoperative adjuvant chemoradiotherapy and were followed up for 3 years after treatment. The 3-year survival was recorded. The surviving patients were included in a good prognosis group, and the deceased ones were assigned to a poor prognosis group. The levels of miRNAs (miR-182, miR-155, and miR-217) and traditional breast cancer proteins [estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor-2 (CerbB-2/HER-2), and cell proliferation factor-67 (Ki-67)] were measured. Receiver operating characteristic (ROC) curve was plotted to investigate the predictive value of miRNA levels for poor prognosis.

Results
The relative expressions of miR-182, miR-155 and miR-217 were negatively correlated with ER and PR (r<0, P<0.05), but positively correlated with positive Ki-67 expression (r>0, P<0.05). High relative expressions of miR-182, miR-155 and miR-217 and positive Ki-67 expression were risk factors for poor prognosis, and the positive expressions of ER and PR were protective factors (OR<1, P<0.05). The areas under the curves of the relative expressions of miR-182, miR-155 and miR-217 and combined detection for predicting poor prognosis all exceeded 0.70. The combined detection had the highest predictive value.

Conclusions
The high expressions of miR-182, miR-155 and miR-217 are correlated with the expressions of traditional breast cancer proteins ER, PR, and Ki-67, and may predict the prognosis of breast cancer patients.
Assessment of ocrelizumab impact on neurofilament levels in multiple sclerosis patients
Authors: Maier Smaranda , Huțanu Adina , Bărcuțean Laura , Sărmășan Emanuela , Bălașa Rodica 
Published: July 2024

Abstract

Background
Multiple sclerosis (MS) is a debilitating neurological disease characterized by inflammation, demyelination, and neurodegeneration in the central nervous system. Despite extensive research, the pathology of MS remains incompletely understood. Ocrelizumab (OCRE), a monoclonal antibody targeting CD20-positive B cells, has shown efficacy in relapsing (RR) and primary progressive (PP) MS. Neurofilaments (Nf) are emerging biomarkers of neuroaxonal injury, reflecting disease activity and treatment response in MS. This study aimed to assess the impact of OCRE on serum Nf levels (NfLs) in RRMS and PPMS patients and explore factors influencing treatment response.

Methods
A prospective study included 23 RRMS and PPMS patients initiating OCRE and 23 healthy controls. Serum NfLs were quantified using ELISA. Statistical analyses evaluated changes in NfLs and factors influencing treatment response.

Results
MS patients exhibited significantly higher NfLs than controls. OCRE treatment led to a significant reduction in NfLs after one cycle. Age and gender influenced treatment response, with older patients and females experiencing greater NfL reduction. Disability level and disease duration did not significantly affect NfLs reduction. Both RRMS and PPMS patients showed decreased NfLs levels with OCRE treatment.

Conclusions
In conclusion, OCRE demonstrated efficacy in reducing NfLs levels in RRMS and PPMS patients after one cycle, with potential age and gender-related variations in treatment response. Larger longitudinal studies are needed to further elucidate OCRE’s mechanisms and implications for personalized MS treatment.
Implementing essential requirements of the ISO 17043:2023 for a proficiency testing provider as a step towards accreditation achievement
Authors: Ilinca Radu , Luțescu Dan Adrian , Sfeatcu Ruxandra Ionela , Iosif Laura , Wagner Andreea , Țâncu Ana Maria Cristina 
Published: July 2024

Abstract
Successful participation in Proficiency Testing/Interlaboratory Comparison (PT/ILC) schemes is a method to ensure validity of results for any laboratory. It is also a component of a complex of means for demonstrating technical competence of a laboratory as an organization. The new accreditation standard ISO 17043 for PT providers together with the newly updated ILAC Policy of PT participation introduce a different perspective on the activity of PT provider in regard to quality assurance.
Technical and management requirements from the ISO 17043:2023 that are essential for a competent activity of PT/provider are identified with a rationale for their increased importance. This importance is related both to the practical impact on the PT/ILC providers’ customers (laboratories) activity and laboratory benefits of participation in PT/ILS schemes besides the traditional qualitative and quantitative interpretation of their participation.
Identified requirements are accompanied by a practical and explained potential implementation strategy which is aligned with the ILAC Policy on PT/ILC participation.
Successful implementation of the essential requirements of the ISO 17043:2023 is a necessary step for any PT/ILC provider that seeks credibility on the proficiency testing market. Such implementation may also be an important step towards full implementation of the ISO 17043:2023 and achieving accreditation thus benefiting from full confidence in the activities of the provider.
Up-Regulation of microRNA-34a in Women with Systemic Lupus Erythematosus
Authors: Abdullah Wissam L. , Abed Reema M. 
Published: July 2024

Systemic Lupus Erythematosus (SLE) is a chronic systemic autoimmune disease with multiple contributing factors. It is characterized by the immune system's inability to tolerate autoantigens such as nuclear antigens. The objective of this study is to evaluate the expression of microRNA-34a in relation to the incidence and occurrence of SLE in Iraqi women using quantitative real-time PCR and to determine its potential relationship with various demographic and laboratory parameters and disease activity. This investigation enrolled 100 healthy controls with a mean age of 31.68 years and 100 SLE patients, all of whom were women with a mean age of 32.85 years and a disease duration of 9.00 (6.75) years. The mean of the Systemic Lupus Erythematosus disease activity index (SLEDAI-2k) score was 10.860±3.275. Erythrocyte sedimentation rate, C-reactive protein, urea, and creatinine were significantly higher (50.00 vs. 10.00 mm/h, 16.70 vs. 0.650 mg/dl, 58.00 vs. 33.00 mg/l, and 1.550 vs. 0.700 mg/l, respectively), while hemoglobin, white blood cells, and Complement 3 and Complement 4 were significantly lower (8.40 vs. 13.00 g/dl, 3.500 vs. 6.800 x 109 /L, 74.00 vs. 130.00 mg/dl, and 10.00 vs. 13.50 mg/dl, respectively) in patients with SLE compared with controls (P≤ 0.001). The analysis of anti-nuclear antibodies (ANA) in patients showed that 89% have ANA and 95% have anti-double-stranded DNA (anti-dsDNA). Also, the findings revealed a significant increase in microRNA-34a expression with fold change (5.19 ±0.48) when compared to the fold change mean in controls (1.00 ±0.00). There is no evidence for any correlation between microRNA-34a fold change and any laboratory or demographic examination of the illness in the present study except for age and BMI. In addition, receiver operating characteristic (ROC) analysis was performed on SLE patients to establish the diagnostic accuracy of microRNA-34a in differentiating SLE patients from controls. The specificity and sensitivity of microRNA-34a were 98% and 100%, respectively. The area under the curve (AUC) was 0.990, and the cutoff point was 1.050. This indicates that the identified microRNA-34a may represent strong biomarkers for SLE disorders.
Generalizations of Supplemented and Lifting Semimodules
Authors: Alwan Ahmed H. 
Published: July 2024

In this paper, principally supplemented (-supplemented), and principally lifting (-lifting) semimodules are defined as generalizations of principally supplemented (-supplemented), and principally lifting (-lifting) modules. Let be a semiring. An -semimodule is called a principally supplemented (-supplemented) semimodule, if for all there exists a subsemimodule of with and small (-small) in . In this paper, we examine properties of principally -supplemented semimodules and generalize results on principally -supplemented modules to semimodules. Besides, we characterize -semiperfect semimodules as a generalization of -semiperfect modules.
Noise levels in the «Hospital Universitario del Valle» newborn intensive care unit «Cirena», Cali, Colombia.
Authors: Fajardo Diana Lorena , Gallego Sonia Yurany , Argote Luz Ángela 
Published: July 2024

Introduction: The high risk newborn babies requires special care and treatment then they have to be move to a exclusive area of the new born intensive care unit (Cirena), where they stay in the hospital during long periods of time and they are more vulnerable to multiple physics and environmental aggressions like noise that can make a negative influence on their clinical situation and post evolution. Objective: Determine level and noise levels in the newborn intensive care unit (Cirena), to planning nurse care to make a contribution to the well being of the new born babies. Methodology: This is a prospective descriptive study that quantified the sound intensity in different areas of the unit, with a digital sound meter, the study identifies some hours of the day and the noise increment related activities in CIRENA, according to international standards. The statistic analysis was made with SPSS program V 11.5. Results: The study shows that the CIRENA´s noise level is above of the allowed limit, the maximum registered value was 73.6 dB and the minimum value was 46.5 dB, the main source of noise was the people in the room. All the health team needs to keep in mind that is necessary to apply strategies to decrease the noise level and in this way, reduce the stress level for kids in the hospital.