bluuebunny/crossref_metadata_2025_split huggingface dataset:
Intraoperative severe gastric venous congestion during total pancreatectomy with replaced common hepatic artery: a case report
Authors: Yamanaka Takahiro , Araki Kenichiro , Suzuki Hideki , Osawa Hidenobu , Shirabe Ken 
Published: August 2024

Abstract
Background
Gastric venous congestion (GVC) is one of the complications of total pancreatectomy (TP). Here, we report a case of intraoperative severe GVC during TP with a replaced common hepatic artery (RCHA).

Case presentation
A 65-year-old female patient was diagnosed with intraductal papillary mucinous carcinoma. Her CHA branched from the superior mesenteric artery as RCHA. She underwent subtotal stomach preserving TP. The tumor was resected with splenic artery (SpA) and total gastric vein transections. Severe GVC and bleeding from the stomach tube occurred intraoperatively. A strong pulsation was observed in the left gastric artery (LGA), and we suspected an increased blood flow from the celiac artery (CeA) to the LGA after SpA resection. Total gastrectomy (TG) was then performed to control the severe GVC-related bleeding. The patient was discharged without complications 19 days postoperatively.

Conclusion
TP with RCHA may increase the risk of severe GVC due to increased blood flow from CeA to LGA.
MICROPHERRET: MICRObial PHEnotypic tRait ClassifieR using Machine lEarning Techniques
Authors: Bizzotto Edoardo , Fraulini Sofia , Zampieri Guido , Orellana Esteban , Treu Laura , Campanaro Stefano 
Published: August 2024

Abstract
Background
In recent years, there has been a rapid increase in the number of microbial genomes reconstructed through shotgun sequencing, and obtained by newly developed approaches including metagenomic binning and single-cell sequencing. However, our ability to functionally characterize these genomes by experimental assays is orders of magnitude less efficient. Consequently, there is a pressing need for the development of swift and automated strategies for the functional classification of microbial genomes.

Results
The present work leverages a suite of supervised machine learning algorithms to establish a range of 86 metabolic and other ecological functions, such as methanotrophy and plastic degradation, starting from widely obtainable microbial genome annotations. Tests performed on independent datasets demonstrated robust performance across complete, fragmented, and incomplete genomes above a 70% completeness level for most of the considered functions. Application of the algorithms to the Biogas Microbiome database yielded predictions broadly consistent with current biological knowledge and correctly detecting functionally-related nuances of archaeal genomes. Finally, a case study focused on acetoclastic methanogenesis demonstrated how the developed machine learning models can be refined or expanded with models describing novel functions of interest.

Conclusions
The resulting tool, MICROPHERRET, incorporates a total of 86 models, one for each tested functional class, and can be applied to high-quality microbial genomes as well as to low-quality genomes derived from metagenomics and single-cell sequencing. MICROPHERRET can thus aid in understanding the functional role of newly generated genomes within their micro-ecological context.
Harnessing real-life experiences: the development of guidelines to communicate research findings on Developmental Coordination Disorder/dyspraxia
Authors: Purcell Catherine , Dahl Annie , Gentle Judith , Hill Elisabeth , Kirby Amanda , Mason Abby , McQuillan Victoria , Meek Andrea , Payne Sally , Scott-Roberts Sally , Shaw Krystal , Wilmut Kate 
Published: August 2024

AbstractDevelopmental Coordination Disorder (DCD), also known as dyspraxia, affects 5–15% of school-aged children (Hamilton and Sutton, Am Fam Physician 66:1435, 2002) and significantly impacts a child’s ability to learn motor skills and perform everyday activities efficiently and effectively (Zwicker et al., Eur J Paediatr Neurol 16:573–81, 2012). These motor deficits can have a negative impact on academic performance, vocational choices and leisure pursuits (Zwicker et al., Eur J Paediatr Neurol 16:573–81, 2012) and profoundly impact quality of life (Izadi-Najafabadi et al., Res Dev Disabil 84:75–84, 2019). DCD persists into adulthood (Kirby et al., J Adult Dev 18:107–13, 2011), impacting motor as well as emotional and behavioural status (Tal Saban and Kirby, Curr Dev Disord Rep 5:9–17, 2018). Despite the continued increase in research in the field of DCD, awareness of DCD remains poor (O’Kelly NL., From invisibility to invincibility: Guidelines for supporting families through the diagnosis and journey with developmental coordination disorder, 2012) even though it has higher prevalence rates when compared to, for example, autism spectrum disorder (Yan et al., J Autism Dev Disord :1–7, 2024), which in part may be due to a lack of accessible research findings. A fundamental feature of the research process is disseminating research findings. This should involve community members in design and delivery to ensure the accessibility of research findings.In 2022 the DCD-UK committee established a DCD Research Advisory Group (DCD-RAG) which met over the course of 12 months to: (1) identify issues of inaccessible research findings; (2) determine the need for a repository for research summaries; (3) co-create guidelines for authors and (4) agree a process for reviewing research summaries to be housed on the Movement Matters website. The new co-produced research repository, author guidelines and process were launched at the DCD-UK conference in Manchester 2023 and subsequently shared on social media and through the DCD research email list. The creation of the DCD-RAG and the process that we undertook together to create a non-academic repository for DCD research summaries are described. It is hoped that this repository will enable the wider public, community members and professionals to be able to readily benefit from accessible research, increasing a deeper and broader understanding of the evidence in the field.
Anesthesia management for percutaneous mitral valve repair in a patient with mitochondrial cardiomyopathy and low cardiac function: a case report
Authors: Tashima Koichiro , Hayashi Masakiyo , Oyoshi Takafumi , Uemura Jo , Korematsu Shinnosuke , Hirata Naoyuki 
Published: August 2024

Abstract
Background
Mitochondrial cardiomyopathy occurs when impaired mitochondrial energy production leads to myocardial dysfunction. Anesthetic management in such cases is challenging due to risks of circulatory depression associated with anesthesia and mitochondrial dysfunction induced by anesthetics. Although there are reports of anesthetic management for patients with mitochondrial diseases, there are few reports specifically addressing cardiac anesthesia for patients with mitochondrial cardiomyopathy. We present a case where percutaneous mitral valve repair with MitraClip™ was successfully performed under remimazolam anesthesia in a patient with mitochondrial cardiomyopathy who developed functional mitral valve regurgitation due to low cardiac function and cardiomegaly.

Case presentation
A 57-year-old woman was diagnosed with chronic cardiac failure, with a 10-year history of dilated cardiomyopathy. She was diagnosed with mitochondrial cardiomyopathy 8 years ago. Over the past 2 years, her cardiac failure worsened, and mitral valve regurgitation gradually developed. Surgical intervention was considered but deemed too risky due to her low cardiac function, with an ejection fraction of 26%. Therefore, percutaneous MitraClip™ implantation was selected. After securing radial artery and central venous catheterization under sedation with dexmedetomidine, anesthesia was induced with a low dose of remimazolam 4 mg/kg/h. Anesthesia was maintained with remimazolam 0.35–1.0 mg/kg/h and remifentanil 0.1 μg/kg/min. Noradrenaline and dobutamine were administered intraoperatively, and the procedure was completed successfully without circulatory collapse. The patient recovered smoothly from anesthesia and experienced no complications. She was discharged on the eighth day after surgery.

Conclusion
Anesthesia management with remimazolam appears to be a safe and effective for MitraClip™ implantation in patients with mitochondrial cardiomyopathy.
Testing reliability and validity of the Korean version of Debriefing Assessment for Simulation in Healthcare (K-DASH)
Authors: Chung Seon-Yoon , Park Bu Kyung , Kim Myoung Jin , Rudolph Jenny W. , Fey Mary , Simon Robert 
Published: August 2024

Abstract
Background
Use of the Debriefing Assessment for Simulation in Healthcare (DASH©) would be beneficial for novice debriefers with less or no formal training in debriefing. However, the DASH translated into Korean and tested for psychometrics is not yet available. Thus, this study was to develop a Korean version of the DASH student version (SV) and test its reliability and validity among baccalaureate nursing students in Korea.

Methods
The participants were 99 baccalaureate nursing students. Content validity using content validity index (CVI), construct validity using exploratory factor analysis (EFA) and confirmatory factor analysis (CFA), and internal consistency using Cronbach’s alpha coefficient were assessed.

Results
Both Item-CVIs and Scale-CVI were acceptable. EFA supported the unidimensional latent structure of Korean DASH-SV and results of CFA indicated 6 items converged within the extracted factor, significantly contributing to the factor (p ≤ .05). Items were internally consistent (Cronbach’s α = 0.82).

Conclusion
The Korean version of the DASH-SV is arguably a valid and reliable measure of instructor behaviors that could improve faculty debriefing and student learning in the long term.
Synergistic effect of Metarhizium flavoviride and Serratia marcescens on western flower thrips, Frankliniella occidentalis Pergande (Thysanoptera: Thripidae)
Authors: Koç Muhammed , Bekircan Eski Duygu , Güllü Mustafa , Demir İsmail , Eski Ardahan 
Published: August 2024

Abstract
Background
The western flower thrips (WFT), Frankliniella occidentalis Pergande (Thysanoptera: Thripidae), is an important polyphagous pest in both greenhouses and fields. Due to its wide range of host plants and short life cycle, the pest causes overwhelming damage and has led to the destruction of many crops. The combined use of entomopathogenic microorganisms could be an important option to overcome the difficulties in controlling WFT. The virulence of thirty local entomopathogen isolates was tested on WFT, and possibilities of combined application for WFT control were investigated.

Results
All isolates were virulent for both the second larval stage and the adult stage of WFT. Serratia marcescens Se9 was the most virulent bacterial isolate with a mortality of 54 and 69.6% against the second larval and the adult stages of WFT, respectively. The LC50 values of the Se9 isolate were determined to be 4 × 106 cfu/ml for the second larval stage and 6.3 × 106 cfu/ml for the adult stage. Among the fungal isolates, Metarhizium flavoviride As18 showed a mortality rate of 92.1 and 74.5% against the second larval and the adult stages of WFT, respectively. The LC50 value was determined to be 1.6 × 104 and 7.1 × 104 conidia/ml for the second larval and adult stages of WFT, respectively. The combined application of S. marcescens Se9 and M. flavoviride As18 at different concentrations generally performed better than single treatments, indicating an additive or synergistic interaction. While the single treatment with S. marcescens and M. flavoviride caused a mortality of 20.4 and 49.5%, respectively, the combined application (S. marcescens LC25; M. flavoviride 100 × LC25) resulted in a mortality of 95.7% of the second larval stage. Similarly, the combined application caused 96% mortality in the adult stage, while the single treatments with S. marcescens and M. flavoviride caused 11.3 and 61.3% mortality, respectively.

Conclusion
The study showed that the combined application of S. marcescens (LC25) and M. flavoviride (LC25 × 100) resulted in synergism against both second larval and adult stages of WFT. This is the first study to show that the combination of S. marcescens and M. flavoviride had synergistic potential to suppress the WFT population. In future studies, these microorganisms should be formulated together as biopesticides and tested under greenhouse or field conditions.
Reproductive outcomes in women with advanced endometriosis in fresh versus frozen embryo transfer cycles
Authors: Shoukry Ahmed , Gazeirly Wael Samir El , Khattab Mohamed Abdelkader , Abdelmoneim Hesham Mahmoud Adel 
Published: August 2024

Abstract
Background
ART in women with endometriosis is associated with poor quality of the retrieved oocytes and lower fertilization and pregnancy rates, reflecting that endometriosis may influence fertility by altering the quality of both the oocyte and embryo quality and also by impairing the endometrial receptivity. On comparing endometriosis-affected patients to healthy counterparts, many differences were demonstrated at the endometrial level. Thus, choosing the appropriate method of embryo transfer is of utmost importance, particularly for patients with advanced endometriosis.

Objective
The aim of the present study was to compare the reproductive outcomes between fresh and frozen embryo transfer cycles in women with advanced endometriosis.

Material and methods
A retrospective cohort study was conducted in the period from January 2018 until December 2021 for patients recruited from two IVF centers, Alexandria, Egypt. Careful review of paper and electronic medical records of infertile women (primary, relative, or secondary infertility) aged 18–37 years who were diagnosed with advanced endometriosis by means of laparoscopy and were scheduled for ICSI followed by either fresh embryo transfer (group I) or freeze-all embryos and deferred embryo transfer (group II) of day 5 embryo(s) was included in the study.

Results
Two-hundred and eleven women were eligible and included in the study. Women in each study group were matched regarding baseline characteristics. Clinical pregnancy, implantation, and ongoing pregnancy rates were statistically significantly higher in the group of frozen embryo transfer (p < 0.001). Miscarriage rate was found to be higher in the group of fresh transfer compared to FET group but without a statistical significance (20.9% vs 9.2%, p = 0.072).

Conclusion
In women with advanced endometriosis, freeze-all policy seems to be associated with better implantation, ongoing pregnancy rates.
Relationship between differential auditory sensitivity and central auditory processing among musicians and nonmusicians
Authors: Arthanarieaswaran Susi Priya , Sahayaraj Perpetua Nancy , Chelliah Pushpa Sarona Edwin , Neelamegarajan Devi , Ravirose Udhayakumar , Karupaiah Kamalakannan 
Published: August 2024

Abstract
Background
Music is the art of combining vocals or instruments to form the beauty of expression. Perception of the sounds includes two types of processing: bottom-up and top-down. Earlier studies have reported that musicians outperformed nonmusicians in the discrimination of frequency, intensity, duration, temporal processing tasks, and working memory. The present study compared musicians’ and nonmusicians’ differential sensitivity and auditory processing abilities in children and younger adults.

Methods
A total of 120 participants in the age range of 9–15 years and 18–25 years were recruited for the study and were further divided into four groups: children musicians, children nonmusicians, young adult musicians, young adult nonmusicians group A, B, C, D, respectively. Each group consisted of 30 participants. Further, all the participants were assessed with Differential sensitivity tests such as DLI, DLF, DDT, GDT, and Dichotic CV.

Results
The study revealed a high statistical difference in the DLI, DLF, DDT, GDT, and DCV, indicating that children who learned music had better scores than those who did not. A similar trend was observed for younger adults, wherein musicians scored better than nonmusicians on differential sensitivity and auditory processing abilities.

Conclusion
It was observed that younger adults (musicians and nonmusicians) showed no difference in Dichotic CV, which shows that the maturation and auditory ability of the younger adults are stabilized. Hence, the present study infers that intensive musical training influences superior performance in auditory perceptual tasks.
Rethinking professional boundaries: the climate crisis and brain health
Authors: Conroy Ronán M. , Golden Jeannette , Malone Conor 
Published: August 2024

SummarySince climate change affects psychiatric, neurological and neuropsychological disorders, as well as brain development, the Irish Doctors for the Environment working group on mental health has changed its title and remit to brain health. Mental health professionals need to respond coherently and effectively to the climate crisis. This need challenges traditional professional, disciplinary and academic boundaries and demands a holistic, person-centred approach. We propose that meeting this challenge is vital if the public, policy-makers and legislators are to grasp the full extent of the significance of climate's impact on brain health.
Contribution of severe mental disorders to fatally harmful effects of physical disorders: national cohort study
Authors: Formánek Tomáš , Krupchanka Dzmitry , Perry Benjamin I. , Mladá Karolína , Osimo Emanuele F. , Masopust Jiří , Jones Peter B. , Plana-Ripoll Oleguer 
Published: August 2024

BackgroundIt remains unknown whether severe mental disorders contribute to fatally harmful effects of physical illness.AimsTo investigate the risk of all-cause death and loss of life-years following the onset of a wide range of physical health conditions in people with severe mental disorders compared with matched counterparts who had only these physical health conditions, and to assess whether these associations can be fully explained by this patient group having more clinically recorded physical illness.MethodUsing Czech national in-patient register data, we identified individuals with 28 physical health conditions recorded between 1999 and 2017, separately for each condition. In these people, we identified individuals who had severe mental disorders recorded before the physical health condition and exactly matched them with up to five counterparts who had no recorded prior severe mental disorders. We estimated the risk of all-cause death and lost life-years following each of the physical health conditions in people with pre-existing severe mental disorders compared with matched counterparts without severe mental disorders.ResultsPeople with severe mental disorders had an elevated risk of all-cause death following the onset of 7 out of 9 broadly defined and 14 out of 19 specific physical health conditions. People with severe mental disorders lost additional life-years following the onset of 8 out 9 broadly defined and 13 out of 19 specific physical health conditions. The vast majority of results remained robust after considering the potentially confounding role of somatic multimorbidity and other clinical and sociodemographic factors.ConclusionsA wide range of physical illnesses are more likely to result in all-cause death in people with pre-existing severe mental disorders. This premature mortality cannot be fully explained by having more clinically recorded physical illness, suggesting that physical disorders are more likely to be fatally harmful in this patient group.
Prevalence and risk of psychiatric disorders in young people: prospective cohort study exploring the role of childhood trauma (the HUNT study)
Authors: Stangeland Helle , Aakvaag Helene Flood , Baumann-Larsen Monica , Wentzel-Larsen Tore , Ottesen Akiah , Zwart John Anker , Storheim Kjersti , Dyb Grete , Stensland Synne Øien 
Published: August 2024

BackgroundBetter knowledge about childhood trauma as a risk factor for psychiatric disorders in young people could help strengthen the timeliness and effectiveness of prevention and treatment efforts.AimsTo estimate the prevalence and risk of psychiatric disorders in young people following exposure to childhood trauma, including interpersonal violence.MethodThis prospective cohort study followed 8199 adolescents (age range 12–20 years) over 13–15 years, into young adulthood (age range 25–35 years). Data about childhood trauma exposure from adolescents participating in the Trøndelag Health Study (HUNT, 2006–2008) were linked to data about subsequent development of psychiatric disorders from the Norwegian Patient Registry (2008–2021).ResultsOne in four (24.3%) adolescents were diagnosed with a psychiatric disorder by young adulthood. Regression analyses showed consistent and significant relationships between childhood exposure to both interpersonal violence and other potentially traumatic events, and subsequent psychiatric disorders and psychiatric comorbidity. The highest estimates were observed for childhood exposure to two or more types of interpersonal violence (polyvictimisation), and development of psychotic disorders (odds ratio 3.41, 95% CI 1.93–5.72), stress and adjustment disorders (odds ratio 4.20, 95% CI 3.05–5.71), personality disorders (odds ratio 3.98, 95% CI 2.70–5.76), alcohol-related disorders (odds ratio 3.28, 95% CI 2.06–5.04) and drug-related disorders (odds ratio 4.67, 95% CI 2.87–7.33).ConclusionsThese findings emphasise the importance of integrating knowledge about childhood trauma as a potent risk factor for psychopathology into the planning and implementation of services for children, adolescents and young adults.
One Year Changes in Body Composition and Musculoskeletal Health Following Metabolic/Bariatric Surgery
Authors: Jassil Friedrich C , Papageorgiou Maria , Mackay Emily , Carnemolla Alisia , Kingett Helen , Doyle Jacqueline , Kirk Amy , Lewis Neville , Montagut Gemma , Marvasti Parastou , Brown Adrian , Chaiyasoot Kusuma , Zakeri Roxanna , Mok Jessica , Wingrove Jed , Collet Tinh-Hai , Devalia Kalpana , Parmar Chetan , Makaronidis Janine , Batterham Rachel L 
Published: August 2024

AbstractContextThere are limited comparative studies between one-anastomosis gastric bypass (OAGB) vs Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) on body composition and musculoskeletal health.ObjectiveTo compare changes in body composition, areal bone mineral density (aBMD), muscle strength, and physical function in the first year following OAGB, RYGB, and SG within a UK-based healthcare setting.MethodsThis is a secondary analysis of the BARI-LIFESTYLE trial in 119 adults (77% women; mean ± SD age 45.9 ± 10.3 years; body mass index 43.6 ± 5.5 kg/m2) who underwent OAGB (n = 19), RYGB (n = 39), and SG (n = 61). Body composition and aBMD by dual energy x-ray absorptiometry, handgrip strength, sit to stand (STS) test and 6-minute walking test (6MWT) were assessed presurgery and at 12 months postsurgery.ResultsOAGB, RYGB, and SG exhibited similar reductions in body weight, body fat, and lean mass (within-group comparisons, P &lt; .001). All surgery types were associated with reductions in aBMD at the total hip, femoral neck, and lumbar spine, which were more pronounced after OAGB and RYGB than after SG (all P &lt; .03), though there was no difference between OAGB and RYGB. Despite reductions in absolute handgrip strength, relative handgrip strength, STS test, and 6MWT improved postsurgery (all P &lt; .02), with no differences by surgical procedure.ConclusionOAGB, RYGB, and SG resulted in comparable weight loss, changes in body composition and improvements in relative muscle strength and physical function. OAGB and RYGB, compared with SG, led to greater BMD reductions at clinically relevant sites. Future long-term studies should explore whether these BMD reductions translate into a greater fracture risk.