bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Selective Formation of Non‐conjugated Olefins by Samarium(II)‐Mediated Elimination/Isomerization of Allylic Benzoates.
Authors: Schaefer Sara L. , Roberts Connor L. , Volz Erasmus O. , Grasso Monika R. , O'Neil Gregory W. 
Published: February 2014

AbstractAromatic allylic benzoates are prone to undergo SmI2‐mediated isomerization/elimination to form non‐conjugated olefins with useful selectivity.
ChemInform Abstract: Generation of a Low‐Valent Titanium Species from Titanatrane and Its Catalytic Reactions: Radical Ring Opening of Oxetanes.
Authors: Takekoshi Naoto , Miyashita Kenji , Shoji Noriaki , Okamoto Sentaro 
Published: February 2014

AbstractThe first examples of the C—O bond cleavage of various oxetanes at the 2‐position using low valent titanium alkoxides, generated in situ from the titanatrane complex, Mg, and TmsCl, are presented.
ChemInform Abstract: Efficient Synthesis of Functionalized 6‐Arylsalicylates via Microwave‐Promoted Suzuki Cross‐Coupling Reaction.
Authors: Liu Yu‐Chao , Huang Zhi‐You , Chen Qiong , Yang Guang‐Fu 
Published: February 2014

AbstractThe two‐step procedure gives access to the title compounds starting from iodo salicylate (I) and a broad variety of arylboronic acids within a very short time and good to excellent yields.
ChemInform Abstract: Allylation Reactions of Aldehydes with Allylboronates in Aqueous Media: Unique Reactivity and Selectivity that are Only Observed in the Presence of Water.
Authors: Kobayashi Shu , Endo Toshimitsu , Yoshino Takumi , Schneider Uwe , Ueno Masaharu 
Published: February 2014

AbstractThe reaction proceeds in water and exclusively affords α‐addition products with high dia‐ and enantioselectivities.
ChemInform Abstract: Palladium‐Catalyzed Insertion of α,β‐Unsaturated N‐Tosylhydrazones and Trapping with Carbon Nucleophiles.
Authors: Ye Yu‐Ying , Zhou Ping‐Xin , Luo Jian‐Yi , Zhong Mei‐Jin , Liang Yong‐Min 
Published: February 2014

AbstractA palladium‐catalyzed carbene migratory insertion‐cyclization reactions is described yielding dihydronaphthalene and indane derivatives.
ChemInform Abstract: Synthesis of 2,5‐Disubstituted Dihydrofuran‐3(2H)‐ones via [2,3]‐Sigmatropic Rearrangement of Oxonium Ylides Generated from α‐Oxo Gold Carbenes.
Authors: Han Miyeon , Bae Joohee , Choi Juhee , Tae Jinsung 
Published: February 2014

AbstractThe synthetic value of this procedure is demonstrated by total synthesis of racemic kumausallene (VI) starting from a mixture of IIc and IIIc.
ChemInform Abstract: One‐Pot Three‐Component Synthesis of Indole‐3‐glyoxyl Derivatives and Indole‐3‐glyoxal Triazoles.
Authors: Stefani Helio A. , Vasconcelos Stanley N. S. , Souza Frederico B. , Manarin Flavia , Zukerman‐Schpector Julio 
Published: February 2014

AbstractA general and efficient one‐pot reaction of indole with oxalyl chloride and nucleophiles providing 3‐indolylglyoxyl derivatives is developed.
ChemInform Abstract: Highly Efficient Aluminum Trichloride Catalyzed Michael Addition of Indoles and Pyrroles to Maleimides.
Authors: An Yu‐Long , Shao Zhi‐Yu , Cheng Jian , Zhao Sheng‐Yin 
Published: February 2014

AbstractThe title addition reactions proceed with excellent regioselectivity in the presence of ZnCl2 or AlCl3 as the catalyst to afford 3‐substituted indoles and 2‐substituted pyrroles.
ChemInform Abstract: Multicomponent Reaction for Synthesis of N‐Arylsulfonyl Pyrazoles.
Authors: Khalili Gholamhossein 
Published: February 2014

AbstractArylsulfonyl hydrazones react with dialkyl acetylenedicarboxylates in the presence of nucleophiles such as PPh3, Py or isoquinoline to furnish N‐arylsulfonylpyrazoles (III) in good yield.
ChemInform Abstract: Diethylaminosulfur Trifluoride‐Mediated Intramolecular Cyclization of 2‐Hydroxycycloalkylureas to Fused Bicyclic Aminooxazoline Compounds and Evaluation of Their Biochemical Activity Against β‐Secretase‐1 (BACE‐1).
Authors: Siu Michael , et al. et al. 
Published: February 2014

AbstractA series of unique bicyclic aminooxazolines are synthesized and found to exhibit micromolar inhibition of β‐secretase‐1 (BACE‐1).
ChemInform Abstract: C—H Alkenylation of Azoles with Enols and Esters by Nickel Catalysis.
Authors: Meng Lingkui , Kamada Yuko , Muto Kei , Yamaguchi Junichiro , Itami Kenichiro 
Published: February 2014

AbstractThe utility of this new title reaction is demonstrated by the synthesis of compound (XVI) which is an intermediate in the synthesis of siphonazole B (XVII).
ChemInform Abstract: Catalyst‐Free Facile Synthesis of 2‐Substituted Benzothiazoles.
Authors: Panda Siva S. , Ibrahim Mohamed A. , Oliferenko Alexander A. , Asiri Abdullah M. , Katritzky Alan R. 
Published: February 2014

AbstractThe reaction is conducted under environmentally benign conditions and is suitable for multiple applications in medicinal chemistry and synthesis of specialty chemicals.
ChemInform Abstract: An Unexpected Formation of Pyrazolopyrimidines During the Attempted to Obtain 5‐Substituted Tetrazoles from Carbonitriles.
Authors: Faria Jessica Venancia , dos Santos Mauricio Silva , Vegi Percilene Fazolin , Borges Julio Cesar , Bernardino Alice M. R. 
Published: February 2014

AbstractThe synthesis of new tetrazoles (II) is described.
ChemInform Abstract: A Facile and Rapid Access Towards the Synthesis of 2,3‐Dihydroquinazolin‐4(1H)‐ones.
Authors: Labade Vilas B. , Shinde Pravin V. , Shingare Murlidhar S. 
Published: February 2014

AbstractAn efficient synthetic route to 2,3‐dihydroquinazolin‐4(1H)‐ones (III) using microwave irradiation in the presence of 2‐morpholinoethanesulfonic acid (MES) as organocatalyst is described.
ChemInform Abstract: AlCl3 as an Efficient Catalyst Toward the Synthesis of 1,6‐Dihydropyrazine‐2,3‐dicarbonitrile Derivatives
Authors: Bhosale Shrikar M. , Naik Nilesh H. , Kusurkar Radhika S. 
Published: February 2014

Abstractmulti‐component reaction of diaminomalonitrile, ketones or aldehydes, and isocyanides
ChemInform Abstract: Catalytic and Stereoselective ortho‐Lithiation of a Ferrocene Derivative.
Authors: Steffen Patricia , Unkelbach Christian , Christmann Mathias , Hiller Wolf , Strohmann Carsten 
Published: February 2014

AbstractPreliminary results for desymmetrization of ferrocenylethylamine (I) using a TMCAD‐mediated ortho‐lithiation/quenching sequence is presented.
ChemInform Abstract: A New Deoxyisoaustamide Derivative from the Marine‐Derived Fungus Penicillium sp. JF‐72.
Authors: Quang Tran Hong , Lee Dong‐Sung , Sohn Jae Hak , Kim Youn‐Chul , Oh Hyuncheol 
Published: February 2014

AbstractOne new diketopiperazine alkaloid, deoxydihydroisoaustamide (I), and a new metabolite (II) are isolated together with the already known and structurally related deoxyisoaustamide.
ChemInform Abstract: Isoflavanones from the Stem of Cassia siamea and Their anti‐Tobacco Mosaic Virus Activities.
Authors: Hu Qiu‐Fen , Niu De‐Yun , Zhou Bin , Ye Yan‐Qing , Du Gang , Meng Chun‐Yang , Gao Xue‐Mei 
Published: February 2014

AbstractTwo new isoflavanone derivatives (I) and (II) are isolated together with six already known isoflavanones.
Selective Bromocyclization of 2‐Geranylphenols Promoted by Phosphite–Urea Cooperative Catalysts
Authors: Sawamura Yasuhiro , Nakatsuji Hidefumi , Akakura Matsujiro , Sakakura Akira , Ishihara Kazuaki 
Published: February 2014

ABSTRACTNucleophilic phosphite–urea cooperative catalysts are highly efficient for the bromonium‐induced cyclization of 2‐geranylphenols. Phosphite–N,N’‐dimethylurea catalysts also show moderate activity, probably due to the steric effect of their bent conformation. Chirality 26:355–359, 2014. © 2014 Wiley Periodicals, Inc.
Contemporary prevalence of pretreatment urinary, sexual, hormonal, and bowel dysfunction: Defining the population at risk for harms of prostate cancer treatment
Authors: Resnick Matthew J. , Barocas Daniel A. , Morgans Alicia K. , Phillips Sharon E. , Chen Vivien W. , Cooperberg Matthew R. , Goodman Michael , Greenfield Sheldon , Hamilton Ann S. , Hoffman Karen E. , Kaplan Sherri H. , Paddock Lisa E. , Stroup Antoinette M. , Wu Xiao‐Cheng , Koyama Tatsuki , Penson David F. 
Published: February 2014

BACKGROUNDThe authors investigated the prevalence of pretreatment urinary, sexual, hormonal, and bowel dysfunction in a contemporary, population‐based prostate cancer cohort. They also explored the associations between baseline function and age, comorbidity, and timing of baseline survey completion with respect to treatment.METHODSThe Comparative Effectiveness Analysis of Surgery and Radiation (CEASAR) study is a population‐based, prospective cohort study that enrolled 3691 men with incident prostate cancer during 2011 and 2012. Pretreatment function was ascertained using the Expanded Prostate Cancer Index‐26 (EPIC‐26). Data were stratified by age, comorbidity, and timing of baseline survey completion with respect to treatment. Unadjusted and multivariable linear regression analyses were performed to evaluate the relations between exposures and pretreatment function.RESULTSAfter applying exclusion criteria, the study cohort comprised 3072 men. A strikingly high proportion of men reported inability to obtain erections satisfactory for intercourse (45%) and some degree of urinary incontinence (17%) at baseline. Sexual function was particularly age‐sensitive, with patients aged ≤60 years reporting summary scores in excess of 30 points higher than patients aged ≥75 years (P < .001). Compared with the healthiest men, highly comorbid patients reported less favorable function in each domain, including urinary incontinence (summary score, 89.5 vs 74.1; P < .001) and sexual function (summary score, 70.8 vs 32.9; P < .001). Although statistically significant differences in summary scores were identified between patients who completed the baseline questionnaire before treatment (52%) versus after treatment (48%), the absolute differences were small (range, 1‐3 points).CONCLUSIONSPatients with newly diagnosed prostate cancer exhibit a wide distribution of pretreatment function. The current data may be used to redefine the population “at risk” for treatment‐related harms. Cancer 2014;120:1263–1271. © 2014 American Cancer Society.
Vitamin D receptor FokI gene polymorphisms may be associated with colorectal cancer among African American and Hispanic participants
Authors: Sarkissyan Marianna , Wu Yanyuan , Chen Zujian , Mishra Dhruva K. , Sarkissyan Suren , Giannikopoulos Ioannis , Vadgama Jaydutt V. 
Published: February 2014

BACKGROUNDVitamin D plays a role in cancer tumorogenesis and acts through the vitamin D receptor (VDR). Although African Americans have the lowest serum vitamin D levels, supplementation has not yielded a significant improvement in cancer. Gene polymorphisms in VDR may play a role. There is a dearth of information on VDR gene polymorphisms and colorectal cancer (CRC) among under‐represented ethnic groups. In this study, the authors examined whether VDR gene single nucleotide polymorphisms (SNPs) were associated with CRC in predominately African American and Hispanic study participants.METHODSBlood samples were collected from 378 participants, including a group of 78 patients with CRC (cases), a group of 230 noncancer participants without polyps (controls without polyps), and a group of 70 noncancer participants with polyps (controls with polyps). The 4 polymorphic SNPs in VDR (FokI, BsmI, TaqI, and ApaI) were assessed using the polymerase chain reaction‐restriction fragment length polymorphism method.RESULTSThere was a significant association of the VDR‐FokI FF genotype with CRC cases (odds ratio, 2.9; P = .036) compared with the controls without polyps. The most common VDR‐FokI genotype in the overall study population was the FF genotype (46%). However, upon breakdown by ethnicity, the FF genotype was the most common in African American participants (61%), and the Ff genotype was the most common in Hispanic/Latino participants (49%). When the association was assessed in a multivariate model, there was no significant association with any VDR polymorphism and CRC cases (P > .05). The other 3 polymorphic variants of VDR (BsmI, TaqI, and ApaI) were not associated with CRC.CONCLUSIONSThe results from this study suggest that genetic variation of the VDR‐FokI SNPs may influence CRC risk, particularly in African American cohorts. Cancer 2014;120:1387–1393. © 2014 American Cancer Society.
Exploring the effects of spatial autocorrelation when identifying key drivers of wildlife crop‐raiding
Authors: Songhurst Anna , Coulson Tim 
Published: February 2014

AbstractFew universal trends in spatial patterns of wildlife crop‐raiding have been found. Variations in wildlife ecology and movements, and human spatial use have been identified as causes of this apparent unpredictability. However, varying spatial patterns of spatial autocorrelation (SA) in human–wildlife conflict (HWC) data could also contribute. We explicitly explore the effects of SA on wildlife crop‐raiding data in order to facilitate the design of future HWC studies. We conducted a comparative survey of raided and nonraided fields to determine key drivers of crop‐raiding. Data were subsampled at different spatial scales to select independent raiding data points. The model derived from all data was fitted to subsample data sets. Model parameters from these models were compared to determine the effect of SA. Most methods used to account for SA in data attempt to correct for the change in P‐values; yet, by subsampling data at broader spatial scales, we identified changes in regression estimates. We consequently advocate reporting both model parameters across a range of spatial scales to help biological interpretation. Patterns of SA vary spatially in our crop‐raiding data. Spatial distribution of fields should therefore be considered when choosing the spatial scale for analyses of HWC studies. Robust key drivers of elephant crop‐raiding included raiding history of a field and distance of field to a main elephant pathway. Understanding spatial patterns and determining reliable socio‐ecological drivers of wildlife crop‐raiding is paramount for designing mitigation and land‐use planning strategies to reduce HWC. Spatial patterns of HWC are complex, determined by multiple factors acting at more than one scale; therefore, studies need to be designed with an understanding of the effects of SA. Our methods are accessible to a variety of practitioners to assess the effects of SA, thereby improving the reliability of conservation management actions.
Wind‐Disturbance‐Based Control Approach for Blimp Robots
Authors: Furukawa Hayato , Shimada Akira 
Published: February 2014

SUMMARYBlimps have some advantages, for example, that they do not need driving forces to float and can move in three‐dimensional space. However, it is not easy to control them since they are underactuated systems with nonholonomic constraints. Some papers have presented control technologies, but the technologies need impractical conditions. Furukawa and colleagues presented a blimp control technology considering a nonholonomic situation, but it cannot be used to control blimps in the presence of wind disturbances. This paper introduces a wind‐observer‐based control approach that involves the consideration of wind disturbances. A controller based on the proposed approach can generate a driving force in the direction opposite to that of a wind disturbance and help a blimp move against the wind.
Optimal Design of Buffer Material in the Geological Disposal of Radioactive Wastes Using the Satisficing Trade‐off Method and a Self‐Organizing Map
Authors: Okamoto Takashi , Hanaoka Yuya , Aiyoshi Eitaro , Kobayashi Yoko 
Published: February 2014

SUMMARYIn this paper, we consider the use of a multi‐objective optimization method in order to obtain a preferred solution for the buffer material optimal design problem in the high‐level geological disposal of radioactive waste. The buffer material optimal design problem is formulated as a constrained multi‐objective optimization problem. Its Pareto optimal solutions are distributed evenly over the entire feasible region. Hence, we develop a search method to find a preferred solution easily for a decision maker from the Pareto optimal solutions, which are distributed evenly and broadly. In the preferred solution search method, a technique for visualization of a Pareto optimal solution set using a self‐organizing map is introduced into the satisficing trade‐off method, which is an interactive method for obtaining a Pareto optimal solution that satisfies a decision maker. We confirm the effectiveness of the preferred solution search method in the buffer material optimal design problem. © 2014 Wiley Periodicals, Inc. Electr Eng Jpn, 187(2): 17–32, 2014; Published online in Wiley Online Library (wileyonlinelibrary.com). DOI 10.1002/eej.22634
Iterative α‐Glycosylation Strategy for 2‐Deoxy‐ and 2,6‐Dideoxysugars: Application to the One‐Pot Synthesis of Deoxysugar‐Containing Oligosaccharides
Authors: Chen Jiun‐Han , Ruei Jyh‐Herng , Mong Kwok‐Kong Tony 
Published: February 2014

AbstractThis paper describes the development of an iterative and α‐selective glycosylation method for 2‐deoxyglycosyl and 2,6‐dideoxythioglycoside donors based on the DMF modulation concept. We used NMR spectroscopy to probe the 2‐deoxyglycosyl imidinium intermediate and elucidated the conditions to decrease the formation of glycal and thus to increase the reaction yields. Further elaboration of the glycosylation method opened the gate for an iterative one‐pot synthesis of 2‐deoxy‐ and 2,6‐dideoxyglycoside‐containing oligosaccharides.
Seismic assessment of damaged piloti‐type RC building subjected to successive earthquakes
Authors: Shin Jiuk , Kim JunHee , Lee Kihak 
Published: February 2014

SUMMARYBuilding structures damaged by a seismic event may be exposed to the risk of aftershocks or another event within a certain period. In this paper, the seismic assessment of damaged piloti‐type RC buildings was carried out to evaluate probabilistic retrofitting effects under successive earthquakes. First, a framework to evaluate the effectiveness of retrofitting was proposed, and then the proposed methodology was demonstrated with a structure retrofitted with buckling‐restrained braces (BRBs). For consideration of realistic successive earthquakes, past records measured at the same station were combined. Within the framework, a series of nonlinear time history analyses were performed for an as‐is model subjected to single earthquake, a damaged model subjected to successive earthquakes, and a damaged model retrofitted with BRBs subjected to successive earthquakes. In addition, fragility analysis was systematically applied in the framework for evaluation of effectiveness of the retrofitting strategy. The proposed framework was capable of quantifying the influence of successive earthquakes and evaluating the effectiveness of BRB retrofitting by considering the severity of the first earthquake damage and the hysteresis behavior of the retrofit element. Copyright © 2014 John Wiley & Sons, Ltd.
The Prevalence of Binge Eating Disorder in a Sample of College Students in the North of Portugal
Authors: Ribeiro Mónica , Conceição Eva , Vaz Ana Rita , Machado Paulo P. P. 
Published: February 2014

AbstractBinge eating disorder (BED) has important associated comorbidities and has been recently considered as a diagnostic category in the Diagnostic and Statistical Manual of Mental Disorders – Fifth Edition. This study investigates the prevalence of BED in a sample of college students using a two‐stage design. Between October 2008 and July 2009, 805 students attending a public college campus completed the Questionnaire on Eating and Weight Patterns – Revised to screen for possible cases. Eighty‐five students meeting key criteria for BED were invited for a second stage interview using the Eating Disorder Examination. At stage 1, 9.6% of the subjects reported binge eating episodes. At stage 2, a prevalence rate of 0.5% for BED was found, and 1% if the criterion for large amount of food was excluded. Copyright © 2014 John Wiley & Sons, Ltd and Eating Disorders Association.
Landscape response to tectonic and climatic forcing in the foredeep of the southern Apennines, Italy: insights from Quaternary stratigraphy, quantitative geomorphic analysis, and denudation rate proxies
Authors: Gioia Dario , Gallicchio Salvatore , Moretti Massimo , Schiattarella Marcello 
Published: February 2014

ABSTRACTWe present new data about the morphological and stratigraphic evolution and the rates of fluvial denudation of the Tavoliere di Puglia plain, a low‐relief landscape representing the northernmost sector of the Pliocene‐Pleistocene foredeep of the southern Apennines. The study area is located between the easternmost part of the southern Apennine chain and the Gargano promontory and it is characterized by several orders of terraced fluvial deposits, disconformably overlying lower Pleistocene marine clay and organized in a staircase geometry, which recorded the emersion and the long‐term incision history of this sector since mid‐Pleistocene times. We used the spatial and altimetric distribution of several orders of middle to late Pleistocene fluvial terraces in order to perform paleotopographic reconstruction and GIS‐aided eroded volumes estimates. Then, we estimated denudation rates on the basis of the terraces chronostratigraphy, supported by published OSL and AAR dating. Middle to upper Pleistocene denudation rates estimated by means of such an approach are slightly lower than 0.1 mm yr‐1, in good agreement with short‐term data from direct and indirect evaluation of suspended sediment yield. The analysis of longitudinal river profiles using the stream power erosion model provided additional information on the incision rates of the studied area. Middle to late Quaternary uplift rates (about 0.15 mm yr‐1), calculated on the basis of the elevation above sea level of marine deposits outcropping in the easternmost sector of the study area, are quite similar to the erosion rates average value, thus suggesting a steady‐state fluvial incision. The approach adopted in this work has demonstrated that erosion rates traditionally obtained by quantitative geomorphic analysis and ksn estimations can be successfully integrated to quantify rates of tectonic or geomorphological processes of a landscape approaching steady‐state equilibrium. Copyright © 2014 John Wiley & Sons, Ltd.