bluuebunny/crossref_metadata_2025_split huggingface dataset:
Progress in the environmental risk assessment of plant protection products in Brazil: An overview of birds and mammals and soil organisms proposals
Authors: Cione Ana Paola , Santos Gustavo Souza , Casallanovo Fábio 
Published: July 2024

Abstract
Since 2019, the Brazilian Institute of Environment and Renewable Natural Resources (IBAMA) has actively developed pesticide environmental risk assessment (ERA) frameworks adapted to Brazil's specific ecological contexts. This initiative, supported by funding from the Brazilian Ministry of Justice and in partnership with academic institutions, has led to a concerted effort to establish ERA protocols for various taxa, including birds and mammals, soil organisms, aquatic organisms, and reptiles and amphibians. The outcomes of this initiative were disseminated in two distinct workshops held in February and November of 2023, where the agency showcased its research to the technical-regulatory community. This article synthesizes the proposals for birds and mammals and soil organisms. First, we summarize the agency's proposals for both focal and generic species to be incorporated into the ERA and the methodologies for calculating exposure of these taxa to pesticides through agricultural practices, encompassing seed treatment and foliar applications. On this occasion, IBAMA also disclosed the risk assessment tool that the agency is developing for birds and mammals. IBAMA highlighted the knowledge gaps that must be bridged to progress from preliminary (lower-tier) to more comprehensive (higher-tier) assessments. Regarding soil organisms, during the workshop, the presenters shared findings on the most prevalent species of earthworms and enchytraeids in Brazil. They emphasized the need for additional data collection on a regional scale. The agency has also proposed methods for estimating soil organism exposure to pesticides at a screening level and identified specific data gaps that could be addressed to refine assessments at higher tiers. In summary, the workshop communicated the progress in establishing ERA guidelines, which we encapsulate here to benefit the technical-regulatory community. Integr Environ Assess Manag 2024;20:1793–1799. © 2024 The Author(s). Integrated Environmental Assessment and Management published by Wiley Periodicals LLC on behalf of Society of Environmental Toxicology & Chemistry (SETAC).
Key Points
This brief communication summarizes the key messages conveyed at the workshop organized by the Brazilian Environmental Regulatory Agency (IBAMA) on ERA frameworks for birds and mammals in Brazil. This brief communication summarizes the key messages conveyed at the workshop organized by IBAMA on ERA frameworks for soil organisms in Brazil. The information summarized in this brief communication is a part of a very important shift in the Brazilian regulatory paradigm and may serve as a reference to the technical-regulatory community, not only in Brazil but in Latin America as well. This brief communication may be very useful to the technical-regulatory community in other regions (e.g., USA and Europe) by helping them to follow up on the regulatory changes in Brazil.
Mueller matrix polarimetry approach for noninvasive glucose sensing with absorbance and anisotropic parameters on fingertips
Authors: Huang Po‐Ling , Lo Yu‐Lung , Chen Yu‐Ren , Liu Chih‐Yi 
Published: July 2024

AbstractA Mueller matrix polarimetry system at 532 nm wavelength is developed for noninvasive glucose sensing in turbid media such as human's fingertip. The system extracts mean absorbance and anisotropic properties, demonstrated numerically and experimentally with phantom glucose samples. It is found that mean absorbance (), depolarization index (Δ), and linear dichroism (LD) show linear variation with glucose concentration 100–500 mg/dL. In addition, LightTools simulations indicate proportional scaling of scattering effects with , Δ, and LD. Real‐world tests on fingertip show a strong correlation between these properties and blood glucose levels with a mean absolute relative deviation (MARD) of 12.56% and a correlation coefficient (R2) of 0.875 in prediction by a neural network (NN) model, highlighting the advantages of Mueller matrix in extracting more parameters related to blood glucose.
Harvesting surface (interfacial) energy for tribocatalytic degradation of hazardous dye pollutants using nanostructured materials: A review
Authors: Emmanuel Stephen Sunday , Adesibikan Ademidun Adeola 
Published: July 2024

AbstractIntroductionTribocatalysis, an emerging cutting‐edge technique that uses frictional mechanical energy to activate the catalytic operation of a reaction or material including nanomaterials has garnered the interest of the research community in recent times.AimThis study aimed to critically review original research works directed toward tribocatalytic degradation of various hazardous dye pollutants. Notably, in this review, various nanomaterials and their composites with outstanding tailored degradation profiles are explored for their tribocatalytic degradation efficiency for various dye pollutants. In addition, the effect of various operating factors that are of importance to engineers, industries, and investors for optimization purposes was pragmatically discussed. Also, the effect of electron trapping and radical scavengers alongside the mechanism of tribocatalytic degradation was empirically analyzed.ResultsFrom this work, it was found that the maximum tribocatalytic degradation efficiency was >80% in most cases at an optimum temperature of 20–40°C, time taken of 0.5‐48 hours, and stirring speed of 500‐1000rmp. It was discovered that magnetic stirring enhances the production of •OH, O2•, and h+ by the nanomaterials that are mechanistically responsible for the degradation of the dye pollutants. Also, it was revealed that expended tribocatalyst can be eluted mostly using H2O and can be reused up to 3–10 times while still sustaining degradation efficiency of >80% in most cases and this suggests the industrial scalability and eco‐friendliness potential of this approach.ConclusionIn the end, challenges and research gaps that can pave the way for method improvement and also serve as future research hotspots for researchers were presented.
Explicit discrimination among Brazilian dental students: A multicenter study
Authors: Lopes‐Silva Jhonathan , Paiva Saul Martins , Oliveira Patricia Alves Drummond , Bendo Cristiane Baccin 
Published: July 2024

AbstractObjectiveTo test the association between socioeconomic and sociodemographic status of Brazilian dental students with discriminatory experiences suffered by them.MethodsThis multicenter cross‐sectional study was conducted with 531 undergraduate dental students from four different Brazilian states. The Explicit Discrimination Scale (EDS) was used to measure the experience of discrimination in several daily situations. A questionnaire about sociodemographic and socioeconomic characteristics, form of admission, and permanence in dental schools was developed and validated by experts and six dental students through cognitive interviews. The EDS and questionnaire were sent to students by an online platform using snowball sampling. Descriptive analysis, bivariate tests, and multiple Poisson regression were performed.ResultsAmong the participants, most were female, white, heterosexual, and cisgender. The mean EDS total score was higher among those students who used Brazilian Affirmative Actions for higher education access and permanence (p < 0.005). The multiple analysis indicated that students who were black (prevalence ratio [PR] = 1.484; 95% confidence interval [95%CI]: 1.291–1.705), women (PR = 1.227; 95%CI: 1.030–1.462), had lower monthly income (PR = 1.212; 95%CI: 1.043–1.409) and were lesbian, gay, bisexual, transgender, intersex, queer, pansexual, and plus (LGBTQIAP+) (PR = 1.466; 95%CI: 1.238–1.735) showed a higher probability of discriminatory experiences when compared to white, male and heterosexual students with higher monthly income.ConclusionThere is a racial and social class pattern among dental students. The exclusionary factors such as black race, female gender, lower monthly income and being LGBTQIAP+ make students more vulnerable to discriminatory experiences.
Revolution in diet therapy for inflammatory bowel disease
Authors: Melton Sarah L. , Day Alice S. , Bryant Robert V. , Halmos Emma P. 
Published: July 2024

AbstractUntil recently, diet as a therapeutic tool to treat inflammatory bowel disease (IBD) has not been proven effective. Nearly a century in the making we are in the grips of a revolution in diet therapies for IBD, driven by emerging data revealing diet as a key environmental factor associated with IBD susceptibility, and observational studies suggesting that dietary intake may play a role in the disease course of established IBD. This review summarizes the current evidence for diets trialed as induction and maintenance therapy for IBD. For Crohn's disease, exclusive enteral nutrition and the Crohn's disease exclusion diet with partial enteral nutrition are supported by emerging high‐quality evidence as induction therapy, but are short‐term approaches that are not feasible for prolonged use. Data on diet as maintenance therapy for Crohn's disease are conflicting, with some studies supporting fortification, and others suppression, of certain food components. For ulcerative colitis, data are not as robust for diet as induction and maintenance therapy; however, consistent themes are emerging, suggesting benefits for diets that are plant‐based, high in fiber and low in animal protein. Further studies for both Crohn's disease and ulcerative colitis are eagerly awaited, which will allow specific recommendations to be made. Until this time, recommendations default to population based healthy eating guidelines.
Investigating the role of killer cell immunoglobulin‐like receptors and human leukocyte antigen genetic variants in hepatitis C virus infection
Authors: Li Yuwen , Zeng Tian , Huang Peng , Tan Weilong , Feng Yue , Xia Xueshan , Feng Zepei , Shen Chao , Fan Haozhi , Zhu Chuanlong , Yin Wen , Qian Liqin , Ren Chengrui , Yue Ming 
Published: July 2024

AbstractThe genetic diversity of killer cell immunoglobulin‐like receptors (KIRs) and human leukocyte antigen (HLA) genes influences the host's immune response to viral pathogens. This study aims to explore the impact of five single nucleotide polymorphisms (SNPs) inKIR3DL2andHLA‐Agenes on hepatitis C virus (HCV) infection. A total of 2251 individuals were included in the case‐control study. SNPs includingKIR3DL2rs11672983, rs3745902, rs1654644, andHLA‐Ars3869062, rs12202296 were genotyped. By controlling various confounding factors using a modified logistic regression model, as well as incorporating stratified analysis, joint effects analysis, and multidimensional bioinformatics analysis, we analyzed the relationship between SNPs and HCV infection. The logistic regression analysis showed a correlation betweenKIR3DL2rs11672983 AA,KIR3DL2rs3745902 TT, and increased HCV susceptibility (p < 0.01). Stratified analysis indicated thatKIR3DL2rs1654644 andHLA‐Ars3869062 also heightened HCV susceptibility in certain subgroups. A linear trend of rising HCV infection rates was observed when combiningKIR3DL2rs11672983 AA andKIR3DL2rs3745902 TT (ptrend = 0.007). Bioinformatics analysis suggested these SNPs' regulatory potential and their role in altering messenger RNA secondary structure, implying their functional relevance in HCV susceptibility. Our findings indicate thatKIR3DL2rs11672983 AA andKIR3DL2rs3745902 TT are significantly associated with increased susceptibility to HCV infection.
Development and Testing of the Cyber Malevolent Creativity Behavior Scale
Authors: Liu Chenxi , Li Leqi , Gong Zhe 
Published: July 2024

ABSTRACTIn the current research, we developed and tested a Cyber Malevolent Creativity Behavior Scale (CMCBS), which contains 11 items in three dimensions and aims to measure the degree of individuals' cyber malevolent creativity through malevolent creative behaviors in their lives. The results revealed satisfactory reliability with Cronbach's α coefficient of 0.749 for the overall scale. Specifically, the calculated values were 0.681 for cybershaming, 0.799 for technology abuse, and 0.644 for information manipulation. Data were collected utilizing an online survey (N = 988) in the form of a questionnaire. Using exploratory factor analysis and confirmatory factor analysis, the questionnaire's latent structure and contribution of relevant correlates for explaining cyber malevolent creativity were examined. The CMCBS was significantly and positively correlated with the Malevolent Creativity Behavior Scale, Buss–Perry Aggression Questionnaire, and the Cyberbullying Inventory. This, along with the adequate psychometric properties uncovered here, indicates that it is a useful tool for research on cyber malevolent creativity.
Walking the line between fidelity and flexibility: A conceptual review of personalized approaches to manualized treatments for posttraumatic stress disorder
Authors: Galovski Tara E. , Nixon Reginald D. V. , Kehle‐Forbes Shannon 
Published: July 2024

AbstractThe heterogeneity of the core symptoms of posttraumatic stress disorder (PTSD), high rates of comorbid mental and physical health conditions, and substantial impact of the disorder on functioning and well‐being contribute to complex clinical presentations that can be challenging to treat. Despite these challenges, there are excellent manualized treatments for PTSD with significant empirical support. Although the success of frontline treatments for PTSD is evident, there remains room for improvement as indicated by suboptimal response and attrition rates. To address challenges to optimal therapy outcomes (COTOs), researchers have conducted numerous clinical trials designed to (a) enhance the core structure of treatment protocols to increase flexibility or (b) expand the protocols to address comorbid conditions that inhibit recovery. However, it is implausible to ever conduct the number of enhancement and expansion clinical trials necessary to test manual modifications for the universe of possible COTOs. This conceptual review describes the concept of a personalized model of therapy that leverages a case formulation approach to implementing an evidence‐based treatment for PTSD. This personalized approach provides guidance for the clinician in assessing the patient's COTOs, monitoring them throughout treatment, and relying on the patient's idiosyncratic data to inform treatment decisions, including how and when to diverge from treatment when clinically indicated and ensuring a clear path to return to trauma‐focused work when the COTO is stabilized. This personalized, case formulation approach to treating PTSD provides guidance for adopting a more flexible approach to treating clinically complex patients while ensuring fidelity to the protocol.
Validation of the IOTA ADNEX Model Among Japanese Women Performed by Gynecology Trainees and Ultrasound Specialists
Authors: Kadooka Mizuho , Suemitsu Tokumasa , Ashimoto Kensuke , Takesawa Ami , Matsui Hiroki , Otsuka Isao , Tajima Atsushi 
Published: July 2024

ObjectivesThis study aimed to validate the diagnostic accuracy of the International Ovarian Tumor Analysis (IOTA) Assessment of Different NEoplasias in the adneXa (ADNEX) model in Japanese women, population with a distinct adnexal mass distribution compared with European women, and to evaluate the model's utility by gynecology trainees and ultrasound specialists.MethodsThis single‐center, retrospective study analyzed ultrasound data from January 2017 to March 2020 of 206 women with adnexal masses. Patients who underwent ultrasonography and serum CA‐125 measurement and received postsurgery histological diagnosis were included. The ADNEX model's diagnostic performance was evaluated by two trainees and two specialists using the area under the receiver operating characteristic curve (AUC) and measures of accuracy, sensitivity, specificity, and predictive values for overall performance and each examiner.ResultsOf the 206 included Japanese women, the prevalence of malignancy was 30.1%, including borderline cases. The overall AUC for distinguishing malignancy was 0.848 (95% confidence interval [CI]: 0.817–0.880). The AUC for each examiner ranged from 0.791 to 0.898, with Specialist 2 showing the highest accuracy and sensitivity varying between 0.677 and 0.839. A moderate degree of agreement was noted among the four examiners (Fleiss' kappa was 0.586). The performance of trainees and specialists differed significantly in evaluating the solid tissue and the papillary projections in both malignant and benign groups (P < .001).ConclusionsThe IOTA ADNEX model effectively differentiates benign and malignant adnexal masses in Japanese women. Although the accuracy matched up moderately among the four examiners, better accuracy is expected with training in evaluating solid tissue and papillary projections.
Disease severity in moderate‐to‐severe plaque psoriasis: Results from the Belgian REDISCOVER study
Authors: Hillary Tom , Ghys Liesbeth F. E. , Willaert Fabienne , Swimberghe Sandra , Lecuyer Myriam , Ghislain Pierre‐Dominique , Morrens Joachim , Lambert Jo 
Published: July 2024

AbstractBackgroundIn the Belgian DISCOVER study, conducted in 2011–2012 before the advent of the IL‐17 and IL‐23 Inhibitors, significant undertreatment of patients with plaque psoriasis was reported.ObjectivesThe present study aimed to re‐evaluate the real‐world clinical management and quality of care of moderate‐to‐severe plaque psoriasis patients treated with systemic treatment for at least 24 weeks in clinical practice in Belgium.MethodsThis cross‐sectional and retrospective chart review (REDISCOVER) was conducted in 2021–2022 in private practices and hospitals in Belgium. Patient data were collected during one single visit and included assessments of psoriasis severity (Psoriasis Area Severity Index [PASI], Body Surface Area [BSA], Pruritus VAS scale) and Health‐Related Quality of Life (Dermatology Life Quality Index [DLQI]) and other selected criteria of the Belgian treat‐to‐target (T2T) outcome set.ResultsOf the 306 patients included in the study, 81.4% received treatment with biologicals and 18.6% with traditional systemics, that is, methotrexate or apremilast. IL‐23 Inhibitors (33.7%) and methotrexate (10.8%) were the most prescribed biologicals and traditional systemic, respectively. Between the time of treatment initiation and enrolment, the average PASI and BSA scores decreased, indicating treatment benefits. PASI scores were lower in patients treated with biologicals versus patients treated with traditional systemics. Full achievement of the two Belgian T2T guidelines dimensions was observed in 51% of the patients. Nonetheless, patients were generally satisfied with their treatment (96.1%) and physicians evaluated the treatment as adequate for most patients (87.3%).ConclusionsCompared to 10 years ago, a demonstrable improvement in care of moderate‐to‐severe psoriasis patients was observed in Belgium. This was reflected by substantial achievement of the current treatment goals and high treatment satisfaction by both patients and physicians. While one out of five patients is not achieving targeted goals, and is not treated with a biological, it seems there is still room for improvement.
Hydrogen production from aqueous‐phase reforming of glycerol, sorbitol, and glycine over Pt/Al2O3catalyst in a fixed‐bed reactor
Authors: Kalekar Vinayak N. , Vaidya Prakash D. 
Published: July 2024

AbstractAqueous‐phase reforming (APR) is an interesting technique for generating hydrogen (H2) from biofeeds. In this work, APR of model compounds of wet biomass for H2production was investigated. Glycerol, sorbitol, and glycine were the chosen model compounds. They represent polyols and amino acids in wet biomass such as waste sludge and microalgal biomass. The Pt/Al2O3catalyst was preferred and it was characterized using nitrogen adsorption–desorption, scanning electron microscopy (SEM), transmission electron microscopy (TEM), x‐ray diffraction (XRD), and x‐ray photoelectron spectroscopy (XPS) techniques. APR trials were performed in a continuous fixed‐bed reactor. The reaction conditions chosen for this work were: temperature (T) 453–498 K, pressure (P) 1.2–2.4 MPa, feed concentration 5–15 wt%, and weight hourly space velocity (WHSV) 0.15–0.6 g reactant/(g catalyst h). The best conditions for H2production by the APR process were found to beT = 498 K,P = 2.4 MPa, and feed concentration = 15 wt%. Among the chosen model compounds, glycerol exhibited the highest H2selectivity (82.7%) and H2yield (21.6%) at 498 K. The analysis of kinetic data suggested first‐order reaction kinetics for all the model compounds. The values of activation energy for the reactions with glycerol (55.4 kJ/mol), sorbitol (51.6 kJ/mol), and glycine (45.7 kJ/mol) were determined. Thus, APR is a promising route for effectively producing H2‐bearing gaseous products with high heating value from wet biomass.
Targeted Chemoprofiling and Bioactivity Screening of Willow Bark
Authors: Antoniadou Kyriaki , Hofmann Thomas F. 
Published: July 2024

AbstractThe chemoprofile of willow bark (Salix cortex) for pharmaceutical use was investigated using a combination of in vitro bioassays and analytical techniques. Salicylates were isolated by means of (semi‐)preparative HPLC, and their structure was elucidated by means of LC‐MS and 1D/2D‐NMR experiments. Bioactivity assays identified key compounds of selected Salix extracts contributing to the overall anti‐inflammatory potential. Finally, these phytochemicals were mapped quantitatively by means of LC‐MS/MS.
Covalent Heteroepitaxy of Large‐Area Vertical Hexagonal Boron Nitride for High‐Temperature VUV Photodetectors
Authors: Chen Le , Ma Haoran , Liu Caiyun , Wang Deyu , Han Zhongyuan , Tai Jiajin , Liang Hongwei , Yin Hong 
Published: July 2024

AbstractHexagonal boron nitride (h‐BN) is a van der Waals (vdW) ultrawide bandgap semiconductor with high band‐edge absorption coefficient and chemical/thermal resistance, demonstrating great potential for vacuum ultraviolet (VUV) and UV‐C detection. Hitherto, most of their prevailing applications have exploited epitaxial films and multilayers either grown on substrates or transferred, which tend to form energy‐favorable noncovalent vdW epitaxy. Here, an alternative heteroepitaxy of 2‐inch h‐BN is reported with desirable thickness and vertically aligned vdW layers covalently bonded to sapphire, enabled by activating the inert substrate surface using ion impingement during deposition and the dislocation‐mediated epitaxial transition. The fabricated photodetectors allow efficient photon absorption and carrier collection using a simple planar device design, showing excellent VUV/UV‐C detection performance with ultrafast response of 270 ns/60 µs (rise/decay) and remarkable operating stability until 500 °C. This covalent heteroepitaxy of wafer‐scale h‐BN opens new avenues for optoelectronics and electronics significant to harsh environment applications.