bluuebunny/crossref_metadata_2025_split huggingface dataset:
Acute coronary syndrome in very young adults (<35 years of age) - time to awake and act! A prospective analytical study from South India
Authors: M. Selvaganesh , R. R. Saravanan , S. Satheeshkumar , G. S. Sivakumar , S. R. Veeramani , S. Arul A. , S. Balasubramanian 
Published: June 2024

Background: Acute coronary syndrome in very young adults (<35 yrs) was considered as an uncommon entity, recently shows rising incidence especially in India. Hence we planned this study with the aim, to investigate the incidence, clinical, angiographic profile and outcome of ACS in this population.
Methods: This is a prospective analytical study included patient <35 yrs with ACS admitted to cardiology department in a tertiary hospital of South India. Risk factors, clinical, angiographic profile and follow up data were recorded and analyzed.
Results: Among the total 2180 patients with ACS, 5.8% (n=127) were very young adults. Youngest one was 11 yrs old with coronary anomaly. Median age was 30yrs (SD±3) and only 8.6% (n=10) were obese. Smoking, male sex were the major conventional risk factors followed by low HDL (52%). Family history of premature coronary event seen in 12.9%, hyperhomocysteinemia, elevated LPA and high fibrinogen were observed in 15%, 20% and 3.5% respectively. Anterior wall MI with LAD occlusion was the commonest type (66.3%). Angiographically 31.4% (36/116) had recanalised vessels, coronary anomaly was seen in 3 (2.5%) patients and pure ectasia in 4 (3.4%) patients. Only 2 were undergone primary PCI (1.7%), 61% (n=71) received thrombolytic therapy. Median delay for angiogram was 72 hrs (3 days). In-hospital mortality was 3.4% and 4.5% (n=5) during follow up.
Conclusions: The incidence of ACS among very young adults is on the rising trend (5.8%). Obstructive CAD in 56.9% patients implies the rapid progression of atherosclerosis. With little contribution of novel risk markers of atherosclerosis, smoking and dyslipidemia accelerate the process of premature vascular aging in Indian subcontinent.
A novel approach for anatomical repair of ventral hernia with modified smead jones technique
Authors: Chatterjee Sudipta , Chakraborty Shobhik , Meena Shivani 
Published: June 2024

Background: Ventral hernia repair is the most popular procedures done worldwide. Despite of enough literature, evidence for optimal repair is lacking. We introduced a novel surgical technique for open primary ventral hernia repair, using modified smead jones technique.
Methods: This prospective interventional study conducted at the department of general surgery in Midnapore Medical College and Hospital from October 2022 to February 2023 aimed to assess the efficacy of the modified smead jones technique in open primary ventral hernia repair.
Results: Thirty cases were enrolled, predominantly featuring umbilical hernias in females aged 51-60 years. All cases presented with swelling, pain, and irreducibility. The Modified smead jones technique, employing Prolene no. 1, was utilized, with post-operative complications primarily comprising superficial wound infections managed by IV antibiotics and post-operative pain addressed with adequate analgesia. Recurrence was not observed during follow-ups at 15 days, 1 month, 6 months, and 12 months.
Conclusions: The study concludes that this modified technique offers a straightforward approach with low rates of early and potential reduction in late complications, serving as a viable alternative in both elective and emergency settings for primary ventral hernia repair.
An integrated approach to the quality assessment of special conditions for children with special educational needs
Authors: Rusanova Liliya S. 
Published: June 2024

Оценка качества специальных условий для детей с ограниченными возможностями здоровья в детских садах и школах вызывает исследовательский интерес психологов. В статье рассматриваются результаты анализа создания специальных условий, раскрыта значимость <span class="highlight" title="Возможно разрыв слова">психолого-медико</span>-педагогических комиссий и <span class="highlight" title="Возможно разрыв слова">психолого-педагогических</span> консилиумов образовательных организаций, установлены детерминанты, повышающие эффективность <span class="highlight" title="Возможно разрыв слова">психолого-педагогической</span> помощи ребенку и его семье.
Prospective comparative analysis of the ambulatory blood pressure monitoring changes in patients with hypertension after COVID‑19 in the conditions of the Arctic watch
Authors: Vetoshkin A. S. , Shurkevich N. P. , Gapon L. I. , Kareva M. A. 
Published: July 2024

Objective. To conduct a prospective (2-year) comparative analysis of the dynamics of 24-hour ambulatory blood pressure monitoring (ABPM) in patients with arterial hypertension (HTN) and previous COVID-19 infection working in the conditions of the Arctic watch.Design and methods. In the Medical Unit of Gazprom Dobycha Yamburg LLC (GDY) in the polar shift settlement of Yamburg, 347 patients were examined: 222 men (M) and 125 women (W). All of them underwent ABPM according to the standard protocol in 2019 and 2022. Among them, 261 patients had confirmed COVID-19 between 2020 and 2021 and were treated in the Medical Unit of GDY. Among the examined M and W, according to medical history in 2019, 80 % of M (178 from 222 people) and 66 % of W (82 from 125 people) had elevated blood pressure (BP), p = 0,003. Among patients with HTN, 109 M (61,2 %) and 42 W (51,2 %) survived after COVID-19, p = 0,129. They formed observation group (n = 151). Comparison group included HTN patients without COVID-19 (n = 109).Results. In patients with HTN who had COVID-19, ABPM showed an increase in average daily systolic BP (SBP) values after 2 years: from 134,5 (12,3) to 140,5 (11,8) mmHg (p < 0,0001) and diastolic BP (DBP): from 96,6 (14,0) to 105,1 (13,4) mmHg (p < 0,0001), hypertensive load time indices (TI): TI SBP24 (from 49,5 (29,3) to 61,6 (28,1) mmHg (p < 0,0001) and TI DBP24 from 69,3 (30,5) to 83,4 (21,9) mmHg (p < 0,0001), increase in daytime SBP variability (p = 0,048), decrease in daily SBP indices by 1,2 %: from 7,9 (4,6) to 6,7 (4,3) (p = 0,038) and DBP by 2,0 %: from 9,7 (4,8) to 7,7 (4,7) (p = 0,032). Desynchronization of SBP and DBP rhythms were found by chronobiological analysis.Conclusions. A prospective comparative analysis of the dynamics of ABPM in patients with HTN after COVID-19 in the conditions of the Arctic watch showed an increase in the average daily values of SBP and DBP and their daily variability, deterioration in the daily BP profile with an increase in the “night peaker” phenotype. In patients with HTN who did not have COVID-19, a prospective analysis of ABPM showed a significant increase in DBP and average daily hypertensive load of DBP, which may contribute to further cardiovascular remodeling. In patients with HTN who have recovered from COVID-19, desynchronization processes of SBP and DBP rhythms intensify, which requires an in-depth analysis of the chronobiological structure of the rhythm BP.
E-training environment for developing Capstone teaching skills for STEM teachers in Egypt
Authors: Anbar Noha , Hegazy Tarek , El Naggar Mohamed 
Published: June 2024

The research investigated the efficacy of utilizing an e-training environment to enhance capstone teaching skills among STEM educators. Conducted at Obour STEM School, Cairo, Egypt, the study employed a quasi-experimental design with 27 randomly selected participants. Three instruments were utilized: a list of Capstone teaching skills, a pre-post achievement test, and an observation card assessing skill acquisition in two main fields: EDP Field and Process Management Field. These fields encompassed eight main skills, subdivided into 64 subskills. The researchers conducted pre- and post-testing, initially administering a 70-question pre-test followed by a month-long online training via Microsoft Teams. The training content aimed to address identified needs based on pre-test results. After the training, participants completed a post-test, which was repeated after another month. Results indicated a statistically significant difference (p<=0.05) between pre-test and post-achievement test scores, favoring the latter, suggesting improvement in Capstone teaching skills. Similarly, there was a significant difference (p<=0.05) between pre-test and post-observation card scores, indicating enhanced skill development. Conclusively, the study demonstrated the effectiveness of e-training, particularly employing the SOLE technique, in enhancing capstone teaching skills among STEM educators. Consequently, the researchers recommended the integration of e-training environments in STEM teacher development programs in Egypt.
Balanced Scorecard : Optimisation de la Performance dans le Secteur Public Marocain
Authors: Amine Fraine , Rajae Sabhi , Noureddine Abdelbaki 
Published: June 2024

L'article analyse l'introduction de la Nouvelle Gestion Publique (NGP) au Maroc, en mettant l'accent sur la mise en œuvre du Balanced Scorecard (BSC) pour relever les défis du secteur public. Malgré les critiques sur sa standardisation, le BSC a été adopté dans le but d'instaurer une culture de la performance ; l’étude montre que le BSC a permis d'améliorer la gestion performante des organisations publiques marocaines. Grâce à une évaluation globale liant indicateurs financiers et non financiers, le BSC a favorisé une prise de décision plus éclairée. Cependant, des défis persistent, notamment la résistance au changement de la part des acteurs publics et la difficulté à définir des indicateurs de performance pertinents, l'introduction du BSC a renforcé la transparence, la responsabilisation et l'orientation stratégique, mais nécessite une formation continue du personnel et des ressources dédiées pour sa mise en œuvre. Enfin, les résultats suggèrent d'étendre l'utilisation du BSC à d'autres entités du secteur public en adoptant une approche adaptative et personnalisée afin de maximiser les bénéfices à long terme.

The article analyzes the introduction of the New Public Management (NPM) in Morocco, focusing on the implementation of the Balanced Scorecard (BSC) to meet the challenges of the public sector. Despite criticism of its standardization, the BSC was adopted with the aim of establishing a performance culture; the study shows that the BSC has helped to improve the performance management of Moroccan public organizations. Thanks to a global assessment linking financial and non-financial indicators, the BSC has fostered more informed decision-making. However, challenges remain, notably resistance to change on the part of public players and the difficulty of defining relevant performance indicators. The introduction of the BSC has strengthened transparency, accountability, and strategic orientation, but requires ongoing staff training and dedicated resources for its implementation. Finally, the results suggest extending the use of BSC to other public sector entities, adopting an adaptive and customized approach to maximize long-term benefits.
Honorary Teachers Peformence : Academic Supervision and Organizational Culture in Public Junior High School
Authors: Yuliarti Dinny Puspita , Sari Eliana , Fuad Nurhattati 
Published: June 2024

Teacher performance is one of the important elements in the achievement of quality at school because the teacher is the main component in the educational system that can affect the success of educational goals. Many factors can affect the performance of teachers, among them are seen from the implementation of supervision academic and organizational culture applied in the school environment. This research aims to determine the performance of honorary teachers who are influenced by the academic supervision and culture of organizations in the subdistrict of South Cikarang. The researchers took samples using the Purposive Sampling method of 134 honorary junior high school teachers in the subdistrict of south Cikarang, Bekasi. Data was analyzed using path analysis techniques, to test the hypothesis of the academic supervision variable (X1) on the performance of teachers (Y) and the organizational culture (X2) on the teacher performance (Y), with SPSS 25. Results of the calculation of the path analysis of X1 and Y, obtained t-count = 2,893 > ttable (α=0.05) = 1,978, the result that the variable of academic supervision influences teacher performance. Then the path analysis of X2 and Y, obtained tcount= 2,962 > ttable (α=0.05) = 1,978, showing that the variables of the cultural organization influence teacher performance.
The Brucella effector protein BspF crotonylates TRIM38 to inhibit NF-κB and MAPK signaling pathway.
Authors: Zhu Jinying , Wu Sijiao , Xing Yukai , Li Yuzhuo , Wang Yuqi , Gao Jingbo , Yu Ze , Li Ang , Zhang Huan , Liu Jinling , Chen Xiaoyue , Chen Zeliang 
Published: July 2024

Abstract

Brucellosis is caused by Brucella, which is a highly prevalent intracellular parasite. Type IV secretion system(T4SS) is an important virulence factor of Brucella. T4SS secretes 16 effector proteins, which affect the intracellular transport of Brucella-containing vacuole and regulate the host immune response, helping Brucella to survive and replicate in host cells. In our previous crotonylation proteomics data of HEK-293T cell proteintriggered by BspF, we found BspF crotonylated on TRIM38, which is an important modulator in the pathways of inflammation, and the crotonylation site is K142. Therefore, it is speculated that BspF may be involved in the regulation of host inflammatory response during Brucella infection. In this study, we found BspF-mediated TRIM38K142 crotonylation promotes the ubiquitination of Tumor necrosis factor receptor (TNFR)-associated factor 6 (TRAF6), leading to the degradation of TRAF6, thereby inhibiting the transduction of NF-κB, p38 MAPK and JNK MAPK signaling pathways and inhibits the secretion of pro-inflammatory factors IL-1β, IL-6 and IL-8, which finally helps Brucella to promote intracellular survival. This study provides a new theoretical basis for Brucella to achieve intracellular survival by regulating host innate immunity through T4SS, and provides an important reference for the study of non-histone crotonylation.
Measuring the impact of the African Continental Free Trade Area (AfCFTA) on intra-regional intermediate exports in Africa: A matching approach
Authors: ouakil hicham , OUAZZANI HICHAM EL , MOUSTABCHIR Abdelhamid 
Published: July 2024

Abstract

This study assesses the impact of the implementation of the African Continental Free Trade Area (AfCFTA) on the proportion of intra-regional intermediate exports in Africa. We utilized data from the Initiative for Regional Integration in Africa (IIRA) for the year 2019 and employed a matching method with Caliper. Our findings indicate that the signing of the AfCFTA leads to an average decrease of 0.02374 in the share of intra-regional intermediate exports. However, this relationship is not statistically significant at the 5% level. These results are in contrast with the predictions of the International Monetary Fund (2020) and the findings of other studies. The discrepancy may be attributed to various factors, including the level of implementation of the AfCFTA and the specific reforms needed to maximize its potential long-term benefits, which are areas that warrant further investigation.
JEL classification : F13, F15, O55
The analysis of high-risk factors and clinical characteristics in patients with main pulmonary artery thromboembolism
Authors: Feng Wanjie , He Xing , Fang Siyu , Tang Jialong , Tian Renping , Guo Lu 
Published: July 2024

Abstract

Objective: Main pulmonary artery thromboembolism (MPATE), a subtype of pulmonary thromboembolism (PTE), is characterized by acute onset and high mortality rate. Currently, less is known about the early diagnosis of MPATE. This study aimed to investigate the clinical characteristics and strategies of MPATE, exploring the predictive factors of MPATE.
Methods: Patients with PTE diagnosed by computed tomographic pulmonary angiography (CTPA) were retrospectively included between May 2012 to May 2022 at Sichuan Provincial People's Hospital. Based on imaging characteristics, patients were divided into the MPATE group and Non-MPATE group. The clinical features, treatment strategies, and prognosis were compared between two groups, and high-risk factors in MPATE group were analyzed by multiple logistic regression.
Results: 302 patients with PTE were enrolled, including 142 in MPATE group and 160 in Non-MPATE group. Dyspnea was the most common symptom in both groups, but the proportion of dyspnea was higher in MPATE group (P< 0.05).
Compared with Non-MPATE group, the left ventricular ejection fraction (LVEF), diastolic blood pressure, troponin I (TnI) level, and plasma D-dimer (D-D) level in MPATE group were higher at early admission (P < 0.05). Besides, the MPATE group had a higher proprotion of patients with chronic obstructive pulmonary disease (COPD) and deep vein thrombosis (DVT)(P< 0.05), and the number of patients at moderate-high risk in MPATE group was more than in Non-MPATE group(P< 0.05). The multiple logistic regression analysis showed that COPD (OR= 6.620, 95%CI: 1.825-24.015), dyspnea (OR= 2.300, 95%CI: 1.032-5.124), diastolic blood pressure (OR= 1.031, 95%CI: 1.006-1.057), DVT (OR= 2.330, 95%CI: 1.043-5.209), and LVEF (OR= 1.053, 95%CI: 1.006-1.102) were considered as risk factors of MPATE. In MPATE group, there was a negative correlation between EF and high risk (r= -0.187) or moderate-high risk (r= -0.151), but a positive correlation with low risk (r= 0.181) (P<0.01).
Conclusion: Compared with non-MPATE group, MPATE group were more likely to experience dyspnea, as well as higher levels of diastolic blood pressure and LVEF. Patients with MPATE was also prone to co-occur with comorbidities such as DVT and COPD. These results provided further understanding of MPATE.
Dietary Intake and Associated Factors Among Elderly Persons Receiving Social Assistance Grant for Empowerment (SAGE) in Northern Uganda
Authors: Omoko Jasper 
Published: June 2024

Abstract

Background: The government of Uganda introduced a social assistance grant for empowerment (SAGE) programme specifically targeting elderly people with the aim of improving their livelihoods and nutrition. However, its contribution to nutrient intake is not known because the objective of this study was to determine dietary intake and associated factors among elderly individuals residing in rural areas of northern Uganda.
Method: Using a cross-sectional survey design, 395 elderly individuals aged 65 years and above were sampled purposively. Validated Individual Dietary Diversity (IDDS) and 24-hour dietary recall questionnaires were used to obtain information on dietary quality and nutrient intake adequacy, respectively, as well as demographic characteristics. Descriptive and inferential statistics were computed using the Statistical Package for Social Sciences (SPSS) version 20.
Results. Although the SAGE beneficiaries generally had an improved mean micronutrient intake adequacy ratio (MAR) of 0.61±0.21, there were no statistically significant differences between their MARs and those of the non-SAGE beneficiaries, i.e., 0.58±0.23. Generally, the mean IDDS of this studied population was 5.9±1.6 food groups out of 12 food groups. The consumption of only sugary and sweet foods differed significantly between SAGE beneficiaries and non-SAGE individuals (p<0.05). The results of the general linear model regression showed that only district (β = 0.108, p=0.009) significantly determined the MAR among non-SAGE beneficiaries, while income (β = -0.120, p=0.000) and household size (β = 0.078, p = 0.044) determined the MAR among SAGE beneficiaries. The Poisson regression results indicated that the marital status (β = -0.157, p=0.003), district (β = 0.129, p=0.009) and business status (β = -0.127, p=0.019) significantly determined the IDDS (DQ) of non-SAGE beneficiaries, while education (β = -0.082, p=0.030) determined the DQ among SAGE beneficiaries. Therefore, DQ and NIA do not significantly vary among SAGE and non-SAGE beneficiaries.
Conclusion: Income above 200,000 Ugandan shillings and nutrition education could significantly improve nutrient intake among beneficiaries. The government of Uganda should therefore implement nutrition education during social gatherings, in local health centres and during SAGE distribution to cater to proper food choices, preparation and a good balanced diet.
Using Storytelling to Boost Immunization Awareness: A Pre-Post Study in a Malaysian Primary School
Authors: Othman Nur Sabrina , Bakaruddin Syafi’ah , Noordin Zakiah Mohd , Karuppannan Mahmathi 
Published: July 2024

Abstract

Vaccine hesitancy has led to a decline in immunization rates worldwide, posing a threat to herd immunity. Leveraging storytelling's appeal, a pictorial storybook was designed to improve children's vaccine knowledge. This study evaluated the effectiveness of the storybook in improving vaccine knowledge among children aged 8-9 years. The study employed a one-group pre-test-post-test experimental design. The survey questions were divided into two sections: demographic data and vaccine knowledge consisting of eight questions developed from the content of the storybook. A total of seven classes were randomly selected, and each child read the book with the researcher. The researcher facilitated the survey, ensuring that the participants were not guided towards specific answers. The pre- and post-test data was analysed using the Wilcoxon Signed Rank Test in SPSS version 27.0. The mean score improved from 4.43 to 6.25, and the median score increased from 5.00 to 6.00 showing a significant increase in children's knowledge about vaccines after the intervention. The proportion of children with low vaccine knowledge decreased from 49.1% before the intervention to 6.4% after the intervention. Meanwhile, the percentage of children with high vaccine knowledge increased from 6.7% to 41.2%. The Wilcoxon Signed Rank Test confirmed the statistical significance (p < 0.001) of these findings. The pictorial storybook proved to be an effective tool for enhancing children's vaccine knowledge, validating the use of age-appropriate storytelling in health education. This approach can help address vaccine hesitancy, promote early vaccine literacy, and contribute to improved vaccination rates and better public health outcomes.
A Multiscale Attention Network for the Classification of Lightning Safety Risk Warnings
Authors: Luo Zhiyong , Yin Qiyuan , Xia Min , Li Xiang 
Published: July 2024

Abstract

In order to meet practical business application requirements, this study considered the physical characteristics of lightning, combined with the risk of lightning disasters and disaster responses, to develop a precise classification model for lightning safety risk warnings at target points based on the the multi-scale attention residual network. By analyzing 1404 sets of thunderstorm data from four warning levels in Guangdong region, we trained convolutional neural networks, support vector machines, random forests, extreme gradient enhancement networks, as well as the multi-scale attention residual network (MSA) constructed by our research institute. The results showed that the multi-scale attention residual network has interpretability for lightning safety risk warning, (1) This model proposes an attention mechanism to fuse different features, obtain the importance distribution of different features, and increase the number of neural network layers to extract deeper features. (2) This lightning safety risk warning model is the most reliable among the five models, with an accuracy rate of 93%. (3) For the four-level classification model, it was found that the accuracy of the lightning safety risk warning models based on the MSA remained above 70% (77%), and also achieved the highest recall, lowest standard deviation, and lowest log loss.