bluuebunny/crossref_metadata_2025_split huggingface dataset:
Teacher Educators' Attitudes toward Technology-Enhanced Learning and its Role in the Teaching Process
Authors: Ma Jianjin  , Feng Liyun  , Liu Limin  , Zhou Jie  
Published: August 2024

The major problem of the study is to determine the overall teacher educators’ attitude towards technology-enhanced learning and its incorporation into teaching-learning process. This research is based on a descriptive survey which aimed to analyze teacher educators' attitude towards TEL. Data were collected from teacher educators working in different teacher education colleges and universities in China. The study will consist of 112 teacher educators during the school year 2021-2022. Majority of the students agreed that male teachers have a more structured approach, while female educators use various teaching methods and technology. Most of the students agreed that female educators are patient, while younger teachers are more familiar with current trends and technologies. Further, students value older teachers for their extensive knowledge and approachability on the other hand, professors are tough, demanding, research-oriented, and collaborative.
Rancang Bangun game 2D Pacman Menggunakan Aplikasi Greenfoot Pada Metode Rad
Authors: Stye Ine , Harahap Baginda , Imam Chairul 
Published: August 2024

Perkembangan teknologi dan game yang saat ini semakin pesat setiap waktunya, sehingga banyak muncul beraneka ragam jenis game. Era globalisasi masa kini ditandai dengan penggunaan teknologi komputer dan smartphone yang semakin meluas di semua bidang kehidupan. Dalam penulisan skripsi ini penulis ingin membuat salah satu game yang dulunya banyak dimainkan orang pada waktu itu ialah game Pacman. Pacman adalah sebuah permainan arkade yang dikembangkan Namco dan diterbitkan Midway; dirilis di Jepang pada 22 Mei 1980. Perancang permainan ini adalah Toru Iwatani, yang merupakan karyawan Namco. Pemain harus mengontrol tokoh berwarna kuning bernama Pacman dan membawanya mengelilingi lorong berlika-liku sambil "memakan" titik-titik kecil dan benda-benda khusus lainnya. Pada saat yang sama, terdapat empat "hantu" yang berkeliling di lorong tersebut yang bertugas menangkap Pacman. Untuk alat yang akan digunakan dalam merancang bangun sebuah game yang akan digunakan peneliti dalam pembuatan laporan skripsi ini yaitu Greenfoot, Greenfoot merupakan sebagai aplikasi yang akan digunakan dalam pembuatan. Ini semua dipilih karena aplikasi ini merupakan sebuah program yang dimana pemakai bisa membuat berbagai game berdasarkan kemampuan pembuat, dalam hal ini saya menggunakan aplikasi Greenfoot tersebut, Metode yang digunakan untuk perancang dalam membuat game Pacman ini adalah metode Rapid Application Development (RAD). yang dimana penulis sudah menentukan alur dalam pebuatan, baik itu dari sesi perancangan, sesi desain, sesi pemrograman yang akan digunakan dalam pembuatan game Pacman ini dalam bentuk laporan Skripsi.
PERKEMBANGAN TERKINI MANIFESTASI KLINIS FRAMBUSIA
Authors: Natasha Joanne , Menaldi Sri Linuwih SW , Irawan Yudo , Novianto Endi 
Published: August 2024

Frambusia merupakan penyakit tropis terabaikan yang masih menjadi masalah kesehatan di beberapa negara. World Health Organization (WHO) telah menargetkan eradikasi frambusia tahun 2030 setelah target tahun 2020 belum tercapai. Indonesia masih menjadi salah satu penyumbang kasus frambusia terbesar di Asia Tenggara. Lesi yang bervariasi dan perkembangan gambaran klinis menjadi lesi yang tidak spesifik menyebabkan penegakan diagnosis frambusia menjadi tantangan tersendiri. Pedoman WHO digunakan sebagai acuan untuk menentukan manifestasi klinis frambusia, terbagi menjadi lesi tahap awal (infeksius) hingga lesi tahap lanjut (non-infeksius). Gambaran klinis frambusia seharusnya dapat dikuasai oleh tenaga kesehatan di Indonesia, mengingat penegakan kasus suspek diawali dengan pemeriksaan klinis yang akan dikonfirmasi dengan pemeriksaan serologi. Beberapa surveilans klinis terbaru sudah tidak melaporkan lesi tahap awal sebagai temuan klinis terbanyak, melainkan skar yang sebelumnya dihilangkan dari modifikasi pedoman klinis WHO. Diagnosis yang terlewat mengakibatkan penularan tetap berlangsung.
Cloaking antibodies are prevalent in Burkholderia cepacia complex infection and their removal restores serum killing
Authors: Pham Amy , Tan Kellynn K. Y. , Ledger Emma L. , Smith Daniel J. , Reid David W. , Burr Lucy , Chambers Daniel C. , Wells Timothy J. 
Published: August 2024

IntroductionThe Burkholderia cepacia complex encompasses a group of gram-negative opportunistic pathogens that cause chronic lung infections in people with cystic fibrosis. Distinct from other respiratory pathogens, Burkholderia causes a unique clinical disease in a subset of patients known as ‘cepacia syndrome’, fulminant pneumonia accompanied by bacteraemia and sepsis with a mortality rate of up to 75%. Due to the bacteraemia associated with this disease, the mechanisms that allow Burkholderia to resist the bactericidal effects of serum complement-depending killing are vital. Antibodies usually promote serum killing; however, we have described ‘cloaking antibodies’, specific for lipopolysaccharides that paradoxically protect serum-sensitive bacteria from complement-mediated lysis. Cloaking antibodies that protect Pseudomonas aeruginosa have been found in 24%–41% of patients with chronic lung diseases. The presence of these antibodies is also associated with worse clinical outcomes. Here, we sought to determine the relevance of cloaking antibodies in patients with Burkholderia infection.MethodsTwelve Burkholderia spp. were isolated from nine pwCF and characterised for susceptibility to healthy control serum. Patient serum was analysed for the titre of the cloaking antibody. The ability of the patient serum to prevent healthy control serum (HCS) killing of its cognate isolates was determined.ResultsWe found that several of the Burkholderia strains were shared between patients. Ten of the 12 isolates were highly susceptible to HCS killing. Four of nine (44%) patients had cloaking antibodies that protected their cognate strain from serum killing. Depleting cloaking antibodies from patient serum restored HCS killing of Burkholderia isolates.DiscussionCloaking antibodies are prevalent in patients with Burkholderia pulmonary infection and protect these strains from serum killing. Removal of cloaking antibodies via plasmapheresis, as previously described for individuals with life-threatening Pseudomonas infection, may be a useful new strategy for those with serious and life-threatening Burkholderia infection.
Experimental investigation of enhancement heat dissipation in a novel heat sink under simultaneous impact of impingement jet and magnetic field
Authors: Azadi Shervin , Abjadi Ali , Vahdat Azad Abazar , Ahmadi Danesh Ashtiani Hossein , Afshar Hossein 
Published: August 2024

In today’s world, research on cooling systems that can effectively reduce the cooling time of heat sinks and enhance heat transfer efficiency in a shorter duration is extremely crucial. This experimental study analyzed the cooling time by simultaneously utilizing two cooling techniques. This involved the passage of ferrofluid (Fe3O4/water) through three channels of a heat sink under the influence of a magnetic field, as well as the application of an air impingement jet on the heat sink’s surface. A novel plate-fin heat sink with dimensions of 40 mm (L) × 31.32 mm (W) × 23.5 mm (H) consists of three channels with a diameter of 3 mm for crossing ferrofluid flow and 24 channels on the top of the heat sink for crossing the air was designed and built for the study. The heat sink was exposed to an air impingement jet and an external magnetic field simultaneously. Multiple tests were conducted to determine the convective heat transfer coefficients of the heat sink over time under specific conditions, including a magnetic field of 800 G, a volume fraction of 3%, a Reynolds number of 600 for the ferrofluid, and a mass flow rate of 0.1 kg/s. It was discovered that using the combined method of magnetic field and impingement jet (MF-IJ) compared to cooling by air impingement jet with the simultaneous passage of pure water through the ferrofluid channels (Water-IJ), as well as the ferrofluid flow under a magnetic field without the impingement jet (MF) methods for the designed heat sink, can increase the maximum heat transfer coefficient by 27.4% and 46.4%, respectively. The findings of this study suggest that using the MF-IJ cooling method as a flow control mechanism, along with this innovative geometry, can reduce the cooling time of the heat sinks.
The influence of competitive anxiety of Chinese elite swimmers
Authors: Zhou Yuhang , Jin Zhenyu , Wen Yuhong 
Published: August 2024

BackgroundCompetitive anxiety is a common stress response in competitive environments, influencing sports performance, particularly among elite swimmers.PurposeThis study aims to examine how the characteristics of competitive anxiety impact sports performance across different phases of competitive preparation, alongside its correlation with trait anxiety.MethodsA longitudinal research design, integrating quantitative and qualitative approaches, was employed with 20 swimmers from the Chinese national swimming team participating in both the 2023 Fukuoka World Championships and the Hangzhou Asian Games. The mental readiness form-3 (MRF-3) scale was employed at four time points during the preparation period for longitudinal tracking, complemented by the trait anxiety inventory (T-AI) scale to assess trait anxiety.ResultsThe study identified a negative correlation between cognitive anxiety and somatic anxiety among elite swimmers, with confidence demonstrating a positive correlation. Additionally, there was a significant between trait anxiety and competitive anxiety (p &lt; 0.05). Variations in competitive anxiety were found at different stages of the preparation cycle (F = 15.074; 11.627; 19.552, p &lt; 0.05), impacting sport performance.ConclusionTo optimise performance, tailored psychological intervention programs should be developed and implemented to address the distinct characteristics of competitive anxiety experienced by elite swimmers throughout the preparation phases.
Metabolic profiles associated with exposure to ambient particulate air pollution: findings from the Betula cohort
Authors: Raza Wasif , Öhman Anders , Kanninen Katja M. , Jalava Pasi , Zeng Xiao-wen , de Crom Tosca O. E. , Ikram M. Arfan , Oudin Anna 
Published: August 2024

IntroductionAir pollution is a significant contributor to morbidity and mortality globally and has been linked to an increased risk of dementia. Previous studies within the Betula cohort in Northern Sweden have demonstrated associations between air pollution and dementia, as well as distinctive metabolomic profiles in dementia patients compared to controls. This study aimed to investigate whether air pollution is associated with quantitative changes in metabolite levels within this cohort, and whether future dementia status would modify this association.MethodsBoth short-term and long-term exposure to air pollution were evaluated using high spatial resolution models and measured data. Air pollution from vehicle exhaust and woodsmoke were analyzed separately. Metabolomic profiling was conducted on 321 participants, including 58 serum samples from dementia patients and a control group matched for age, sex, and education level, using nuclear magnetic resonance spectroscopy.ResultsNo statistically significant associations were found between any metabolites and any measures of short-term or long-term exposure to air pollution. However, there were trends potentially suggesting associations between both long-term and short-term exposure to air pollution with lactate and glucose metabolites. Notably, these associations were observed despite the lack of correlation between long-term and short-term air pollution exposure in this cohort. There were also tendencies for associations between air pollution from woodsmoke to be more pronounced in participants that would later develop dementia, suggesting a potential effect depending on urban/rural factors.DiscussionWhile no significant associations were found, the trends observed in the data suggest potential links between air pollution exposure and changes in lactate and glucose metabolites. These findings provide some new insights into the link between air pollution and metabolic markers in a low-exposure setting. However, addressing existing limitations is crucial to improve the robustness and applicability of future research in this area. The pronounced associations in participants who later developed dementia may indicate an influence of urban/rural factors, warranting further investigation.
Preparation, solubility, and anti-inflammatory effects of a complex of diphenylcyclopropenone/β-cyclodextrin derivatives as the treatment of alopecia areata
Authors: Inoue Yutaka , Yoshino Kaede , Kudo Suzu , Kodama Nao , Moteki Hajime , Kimura Mitsutoshi 
Published: August 2024

PurposeTo investigate the preparation of inclusion complexes of diphenylcyclopropenone (DPCP)/β-cyclodextrin (β-CD) derivatives using a three-dimensional (3D) ball mill, and verify the inclusion behavior of the solid dispersion. Additionally, we aimed to investigate the effect of DPCP/β-CDs complex formation on the spleens of male C57BL/6 mice in terms of anti-inflammatory effects.MethodsThe inclusion complexes of DPCP with β-CD and hydroxypropyl-β-cyclodextrin (HPβCD) were prepared using a 3D ball mill. Powder X-ray diffraction (PXRD) and Fourier-transform infrared spectroscopy (FT-IR) were used to evaluate the solid-state properties. The solubility of the prepared DPCP/β-CD and HPβCD complexes and the intermolecular interaction between DPCP and β-CD derivatives in solution were assessed using 1H nuclear magnetic resonance (NMR). Furthermore, the anti-inflammatory effects of DPCPs in the prepared DPCP/CD complexes were investigated using spleens from male C57BL/6 mice, with measurement of interferon gamma (IFN-γ) secretion as an endpoint. Additionally, the protective effects of each drug on NIH-3T3 cells exposed to ultraviolet (UV) irradiation were examined.ResultsSolid-state characterization confirmed the formation of inclusion complexes in the 3D ground mixture (3DGM) (DPCP/β-CD = 1/1) and 3DGM (DPCP/HPβCD = 1/1) complexes through PXRD and IR analysis. The solubility of 3DGM (DPCP/β-CD = 1/1) and 3DGM (DPCP/HPβCD = 1/1) was 17.5 μg/mL and 58.4 μg/mL, respectively, indicating higher solubility than that of DPCP alone. NMR analysis of 3DGM samples suggested that DPCP/β-CD and DPCP/HPβCD form inclusion complexes at a molar ratio of 1/1 but with different inclusion modes. Regarding the anti-inflammatory activity of DPCP, 3DGM (DPCP/HPβ-CD) showed anti-inflammatory effects at lower doses compared to 3DGM (DPCP/β-CD) in terms of IFN-γ and NIH-3T3 cells injured by UV irradiation.ConclusionWe successfully formed inclusion complexes of DPCP/β-CD and DPCP/HPβCD using the 3D ground mixture method. NMR analysis suggested that DPCP/β-CD and DPCP/HPβCD form inclusion complexes at a molar ratio of 1/1 but with different inclusion modes. The anti-inflammatory activity of DPCP was more pronounced in 3DGM (DPCP/HPβCD) at lower doses compared to that in 3DGM (DPCP/β-CD), indicating that the HPβCD derivatives were more effective in enhancing the anti-inflammatory properties of DPCP.
Comparative Analysis of the Mitochondrial Genome Sequences of Diaporthe longicolla (syn. Phomopsis longicolla) Isolates Causing Phomopsis Seed Decay in Soybean
Authors: Li Shuxian , Hu Xiaojun , Song Qijian 
Published: August 2024

Diaporthe longicolla (syn. Phomopsis longicolla) is an important seed-borne fungal pathogen and the primary cause of Phomopsis seed decay (PSD) in soybean. PSD is one of the most devastating seed diseases, reducing soybean seed quality and yield worldwide. As part of a genome sequencing project on the fungal Diaporthe–Phomopsis complex, draft genomes of eight D. longicolla isolates were sequenced and assembled. Sequences of mitochondrial genomes were extracted and analyzed. The circular mitochondrial genomes ranged from 52,534 bp to 58,280 bp long, with a mean GC content of 34%. A total of 14 core protein-coding genes, 23 tRNA, and 2 rRNA genes were identified. Introns were detected in the genes of atp6, cob, cox1, cox2, cox3, nad1, nad2, nad5, and rnl. Three isolates (PL7, PL10, and PL185E) had more introns than other isolates. Approximately 6.4% of the mitochondrial genomes consist of repetitive elements. Moreover, 48 single-nucleotide polymorphisms (SNPs) and were identified. The mitochondrial genome sequences of D. longicolla will be useful to further study the molecular basis of seed-borne pathogens causing seed diseases, investigate genetic variation among isolates, and develop improved control strategies for Phomopsis seed decay of soybean.
A FORMAÇÃO DO/A ASSISTENTE SOCIAL EM CURSO DE GRADUAÇÃO A DISTÂNCIA: UMA ABORDAGEM REFLEXIVA DO OLHAR DOCENTE
Authors: FERREIRA AZEVEDO RAQUEL DE FÁTIMA , ROJAS ACOSTA ANA 
Published: August 2024

Este estudo teve como tema central o processo de formação do/a assistente social em curso de Graduação a distância. Seu objetivo geral foi verificar se o processo de formação do/a Assistente Social na EAD está em consonância com os princípios e diretrizes que fundamentam a formação do/a assistente social. Para alcançar tal objetivo, adotamos, como método de pesquisa, a abordagem quali-quantitativa, exploratória e descritiva, fazendo uso de fonte primária aplicação de questionário eletrônico e secundárias baseadas na literatura da área do Serviço Social. Para análise dos dados coletados em campo optamos por aplicação do Discurso do Sujeito Coletivo. Os principais resultados encontrados demostraram que a hipótese levantada foi confirmada, na medida em que constatamos que as Instituições de Ensino Superior, por meio dos respectivos Projetos Pedagógicos do Curso de Serviço Social, primam pela observância e aplicabilidade dos princípios e diretrizes que fundamentam a formação profissional do/a assistente social, buscando formar profissionais qualificados para seu exercício. Foram identificadas fragilidades quanto à relação trabalhista entre IES e docentes, em razão da sobrecarga das atividades acadêmicas, sem a compensação salarial adequada para esses fins. Por outro lado, percebe-se a necessidade de contínua capacitação para o uso dos recursos tecnológicos pertinentes a essa modalidade. Visando contribuir a partir desta dissertação elaborou- se um produto técnico que visa capacitar permanentemente o corpo docente de IES que propiciem o seu desenvolvimento e melhore a qualidade da EAD destacando a relevância e o acesso ao ensino dos usuários dessa modalidade formativa.
Palavras-chaves: Formação Acadêmica; Assistente Social; Educação a Distância; Professores Universitários.
Analisis Makna Wail pada Q.S. Al-Ma’un (Study Tafsir Ma’a ̅ni ̇ Qur’an dan Tafsir Sya’ra ̅wi ̅)
Authors: Turohmah Atia , Isnaeni Ahmad , Alghifari Abuzar 
Published: August 2024

<p>Penelitian ini bertujuan untuk mengkaji makna wail yang terdapat pada al-Qur'an surat al-Ma’un. Makna wail biasanya dikaitkan dengan perbuatan yang negatif, tetapi pada aur’an surat al-ma’un inidikaitkan dengan perbuatan yang positif tetapi termasuk dalam kategori perbuatan yang celaka. Untuk mengetahui aspek linguistik pada lafadz wail penulis menggunakan tafsir “Ma’ani Qur’an karya al-Farra”. Lalu untuk melihat konteks sosial pada masyarakat di era klasik hingga dapat diterapkan di era kontemporer penulis menggunakan kitab tafsir asy-Sya’rawi. Penelitian ini menggunakan jenis penelitian studi pustaka dengan sifat jenis penelitian kualitatif yang berfokus pada analisis deskriptif teks. Hasil penelitian menunjukkan bahwa makna wail disini yaitu kecelakaan bagi orang yang sholat, bentuk sholat seperti apa yang terancam oleh kecaman Allah swt? Menurut surat tersebut, mereka adalah individu-individu ceroboh yang melakukan sesuatu ketika dilihat orang lain dan menghalangi mereka melakukan aktivitas yang baik. Penafsiran al-Farra’ berfokus pada aspek bahasa dan tafsir klasik sementara asy-Sya'rawi berfokus pada aspek sosial dan kemasyarakatan.</p>
Exploring the Relationship Between Professional Commitment and Emotional Maturity
Authors: Dr. Mandeep Kaur  
Published: August 2024

The vital connection between emotional maturity and professional commitment is examined in this review of the research, along with its implications for both individual and organisational growth. The ability to recognise, comprehend, manage, and make use of one's emotions has a big impact on how well one gets along with others and can handle stress.
Job satisfaction, performance, and loyalty are all correlated with professional commitment, including emotional, continuation, and normative commitment. According to studies, people who are emotionally mature report higher levels of job satisfaction and more positive interpersonal interactions, which strengthen their commitment to their vocation. However, further research is needed to determine whether emotional maturity and commitment to one's career are related. This relationship is being investigated by a study of 200 instructors in Punjab State, however preliminary findings show that more research is necessary because they paint an incomplete picture.
El sentido común en las luchas cotidianas de inmigrantes ilegales en Nueva York
Authors: Gúzman-Aguilar José 
Published: August 2024

El trabajo aborda los procesos hegemónicos que se suscitan entre los inmigrantes mexicanos y el Estado en la ciudad de Nueva York en las últimas cuatro décadas. Describimos las luchas cotidianas desorganizadas y espontaneas que un grupo de sujetos realizan bajo formas creativas para resistir, acomodarse, reinterpretar y agrietar las imposiciones del poder. Concretamente, abordamos el sentido común del proletariado internacional en sus formas de entender y desafiar al castigo de la deportación, sus métodos de reingreso para llevar una vida en las sombras, las diferentes reinterpretaciones y la flexibilización de leyes migratorias para acceder a la legalización, las formas creativas de auto-emplearse y el robo hormigas en sus empleos, las auto-inclusiones en el sistema de salud y el doble uso de los programas de asistencia social.
UMA BREVE ANÁLISE FARMACOLÓGICA SOBRE O USO DE HIPOGLICEMIANTESNA POPULAÇÃO ADULTA COM DIABETES MELLITUS TIPO 2
Authors: Tiago Costa Maia  , Paulo Victor Brasileiro Mota  , Rodolfo Basílio Madeira Neto  , Diana Carla Gouveia Falcão  , Ana Lara Vieira Soares  , Mariana Costa Cavalcante  , José Kilderlan Nascimento de Sousa Filho  , Larissa Bastos Lima  , Francisco Victor Machado Junior  , Samuel de Almeida Cunha  , Márcio Roberto Pinho Pereira  , Maria Angelina Silva Medeiros  
Published: August 2024

Introdução: O diabetes é uma das doenças metabólicas mais frequentes do mundo, sendo considerado uma pandemia. O diabetes é a principal causa de hospitalizações, amputações e necessidade de diálise em pacientes com doença renal crônica no Brasil. O tratamento visa o controle glicêmico e a prevenção de complicações a partir de mudança no estilo de vida e de farmacoterapia. Objetivo: Analisar o uso de hipoglicemiantes em adultos com diabetes mellitus tipo 2 (DM II), em vista de descrever os medicamentos disponíveis, seus mecanismos de ação, eficácia clínica e segurança. Metodologia: Desenvolveu-se um estudo descritivo e qualitativo a partir de revisão bibliográfica nas bases de dados PubMed, SciELO e LILACs entre fevereiro e abril de 2024, sendo selecionados, ao final, 23 trabalhos. Resultados: Os estudos avaliados apresentam diversos dados sobre a terapia medicamentosa da DMII, reforçando informações sobre uso de biguanidas, tiazolidinedionas, glinidas, inibidores da alfa-glucosidase, inibidores da DPP 4, agonistas do receptor de GLP-1, inibidores de SGLT2, insulinas associados aos níveis alvo de HBA1c e às expectativas dos pacientes quanto ao uso desses fármacos. Conclusão: O acompanhamento individualizado do paciente com DM II, como o desenvolvimento contínuo de hipoglicemiantes mais eficazes no controle da doença, podem garantir melhor qualidade de vida para o sujeito, como também tornar estratégias de saúde pública ainda mais promissoras.