bluuebunny/crossref_metadata_2025_split huggingface dataset:
Surgical techniques and treatment outcomes of transoral robotic supraglottic partial laryngectomy
Authors: Park Young Min , Kim Won Shik , Byeon Hyung Kwon , Lee Sei Young , Kim Se‐Heon 
Published: January 2013

AbstractObjectives/Hypothesis:The objective of this prospective study was to confirm the validity of transoral robotic supraglottic partial laryngectomy as a conservation surgery for treating supraglottic cancer.Study design:Prospective case study.Methods:Between December 2009 and November 2011, 16 patients were enrolled in this study. Acoustic waveform analysis was conducted and Voice Handicap Index 10 was measured to assess voice status. Videopharyngogram study and the functional outcome swallowing scale were administered to evaluate swallowing function. Overall survival and disease‐free survival were analyzed using the Kaplan‐Meier method.Results:A negative margin was reported in 88% patients. During the follow‐up period, distant metastasis occurred in one patient at 6 months. The Kaplan‐Meier disease‐free survival at 1 year was 91%. Patients exhibited complete recovery of swallowing ability after an average of 8.3 days. Videopharyngogram study showed aspiration in one patient. The cannula could be removed at an average 11.2 days. The average hospital stay was 13.5 days. Concerning the results of the functional outcome swallowing scale and Voice Handicap Index 10, most patients (90.9%) subjectively reported favorable swallowing and voice function.Conclusions:Transoral robotic surgery was a safe and feasible modality of treating supraglottic cancer. According to our data, transoral robotic surgery demonstrated oncologically and functionally acceptable results in supraglottic cancer patients. Laryngoscope, 2013
The relationship of external and internal sidewall dimensions in the adult Caucasian nose
Authors: Setabutr Dhave , Sohrabi Sohrab , Kalaria Shana , Gordon Kimberly , Fedok Fred G. 
Published: January 2013

AbstractObjectives/hypotheses:Nasal bone length is commonly referenced in the rhinoplasty literature. It has been suggested that short nasal bone length may predispose one to a greater risk of middle vault collapse after rhinoplasty. However, there are limited data available on what constitutes the normal dimensions of these pertinent structures of the nasal sidewall. In addition, no data exist on the gender and ethnic variability of such dimensions. This article reports on measurements of nasal bones and associated structures in adult Caucasian cadavers and their relationships to the nasal sidewall. Furthermore, this study assesses the validity of using surface measurements to approximate the true dimensions of the nasal sidewall structures.Methods:Using 37 adult cadavers, stable, external, nasal landmarks were identified and measured to approximate the dimensions of the nasal bones and upper lateral cartilages. These clinically relevant surface landmarks were then evaluated relative to the direct measurements of dissected nasal bones and upper lateral cartilages in a subgroup of 14 cadavers.Results:For the subgroup, the average length Ainternal(nasal bone) was 24.57 mm; the average measured length Binternal(upper lateral cartilage) was 12.43 mm. Measurements for the subgroup obtained via external landmarks were 20.21 mm (Aexternal) and 15.67 mm (Bexternal), respectively. The relationship of the nasal bone internal length to the external measurement (A) was a ratio of 1.22:1, whereas the internal length of the upper lateral cartilage to the corresponding external measurement (B) was 0.79:1. Average external measurements for the total group were 20.43 mm for the nasal bone and 14.30 mm for the upper lateral cartilage.Conclusions:These data provide useful information to guide the surgeon in avoiding middle vault collapse postoperatively and when evaluating those patients with presurgical middle vault concerns. With less ability to support the upper lateral cartilages, short nasal bones can predispose an individual to middle vault collapse postoperatively.
Teaching and assessing endoscopic sinus surgery skills on a validated low‐cost task trainer
Authors: Steehler Matthew K. , Chu Eugenia E. , Na Hana , Pfisterer Michael J. , Hesham Hosai N. , Malekzadeh Sonya 
Published: January 2013

AbstractObjectives/Hypothesis:To evaluate a previously validated low‐cost sinus surgery task trainer as a means of acquiring basic endoscopic sinus surgery skills and as an objective structured assessment of technical skills (OSATS) to determine procedural competency.Study Design:Prospective blinded study.Methods:Medical students (N = 52) with no sinus surgery experience learned to perform nasal endoscopy and five specific sinus surgery tasks using the validated task trainer. Training included regimented expert instruction, peer instruction/observation, and experienced‐based learning. Pre‐ and post‐training video recordings of nasal endoscopy and five sinus surgery skills were obtained. Two blinded expert otolaryngologists compared pre‐ and post‐training performance using a checklist and global rating scale.Results:Medical student post‐training performance was significantly better than pre‐training performance for each checklist item and global rating scale as calculated by paired t test (P < .001). Interrater reliability and internal consistency were confirmed by Kendall's coefficient of concordance and Cronbach's α calculations, respectively.Conclusions:The sinus surgery task trainer provides an effective means of teaching and evaluating nasal endoscopy and basic sinus surgery skills for novice surgeons. With repeated practice, there was significant improvement in performance. An OSATS using the sinus surgery task trainer suggests that we can effectively measure endoscopic sinus surgery ability with the potential to reliably determine competency outside the operating room.
Environmental Pressures and Technical Efficiency of Pig Farms in Hungary
Authors: Latruffe Laure , Desjeux Yann , Bakucs Zoltán , Fertő Imre , Fogarasi József 
Published: January 2013

ABSTRACTPig farming is one of the strongest polluters of water due to its intensive production and slurry rejection. Several European countries have introduced environmental regulations aiming at reducing the pollution caused by nitrates from agriculture, but not yet Hungary. We investigate how Hungarian pig farms' output and technical efficiency would be affected if such regulations are to be fully implemented in this country. Results indicate that the pollution could be reduced with no impact on the output level, and that pig farmers have incentives to reduce nitrogen pollution in order to increase their efficiency even in the absence of regulation. Copyright © 2013 John Wiley & Sons, Ltd.
Sanfte Festkörperchemie
Authors: Groh Matthias F. , Heise Martin , Kaiser Martin , Ruck Michael 
Published: January 2013

AbstractFestkörperchemische Synthesen umfassen nicht ausschließlich Reaktionen bei hohen Temperaturen. Niedertemperatursynthesen erschließen neue Stoffsysteme und optimieren die Darstellung bekannter Verbindungen in Hinblick auf Reinheit, Ausbeute und Energieeffizienz.
Empfindlich, automatisch und ohne Lösungsmittel
Authors: Laaks Jens , Jochmann Maik A. , Schmidt Torsten C. 
Published: January 2013

AbstractMikroextraktionstechniken bereiten Proben effizient und weitgehend automatisiert für die Gaschromatographie vor. Die Einsatzfelder reichen von der Umwelt‐ und Lebensmittelanalytik bis hin zu biologischen und medizinischen Anwendungen.
Review of the ordered and proportionate flow shop scheduling research
Authors: Panwalkar S.S. , Smith Milton L. , Koulamas Christos 
Published: January 2013

AbstractOrdered flow shop models have appeared in the literature since the mid‐1970s and proportionate flow shop models have appeared since the early 1980s. We provide a detailed review of these models along with some analysis and potential topics for future research. © 2012 Wiley Periodicals, Inc. Naval Research Logistics, 2013
The knapsack problem with a minimum filling constraint
Authors: Xu Zhou 
Published: January 2013

AbstractWe study a knapsack problem with an additional minimum filling constraint, such that the total weight of selected items cannot be less than a given threshold. The problem has several applications in shipping, e‐commerce, and transportation service procurement. When the threshold equals the knapsack capacity, even finding a feasible solution to the problem is NP‐hard. Therefore, we consider the case when the ratio α of threshold to capacity is less than 1. For this case, we develop an approximation scheme that returns a feasible solution with a total profit not less than (1 ‐ ε) times the total profit of an optimal solution for any ε > 0, and with a running time polynomial in the number of items, 1/ε, and 1/(1‐α). © 2012 Wiley Periodicals, Inc. Naval Research Logistics, 2013
Body composition determinants of metabolic phenotypes of obesity in nonobese and obese postmenopausal women
Authors: Peppa Melpomeni , Koliaki Chrysi , Papaefstathiou Athanasios , Garoflos Efstathios , Katsilambros Nicholas , Raptis Sotirios A. , Hadjidakis Dimitrios I. , Dimitriadis George D. 
Published: January 2013

Objective: Although obesity is typically associated with increased cardiovascular risk, a subset of obese individuals display a normal metabolic profile (“metabolically healthy obese,” MHO) and conversely, a subset of nonobese subjects present with obesity‐associated cardiometabolic abnormalities (“metabolically obese nonobese,” MONO). The aim of this cross‐sectional study was to identify the most important body composition determinants of metabolic phenotypes of obesity in nonobese and obese healthy postmenopausal women.Design and Methods: We studied a total of 150 postmenopausal women (age 54 ± 7 years, mean ± 1 SD). Based on a cardiometabolic risk score, nonobese (body mass index [BMI] ≤ 27) and obese women (BMI > 27) were classified into “metabolically healthy” and “unhealthy” phenotypes. Total and regional body composition was assessed with dual‐energy X‐ray absorptiometry (DXA).Results: In both obese and nonobese groups, the “unhealthy” phenotypes were characterized by frequent bodyweight fluctuations, higher biochemical markers of insulin resistance, hepatic steatosis and inflammation, and higher anthropometric and DXA‐derived indices of central adiposity, compared with “healthy” phenotypes. Indices of total adiposity, peripheral fat distribution and lean body mass were not significantly different between “healthy” and “unhealthy” phenotypes. Despite having increased fat mass, MHO women exhibited comparable cardiometabolic parameters with healthy nonobese, and better glucose and lipid levels than MONO. Two DXA‐derived indices, trunk‐to‐legs and abdominal‐to‐gluteofemoral fat ratio were the major independent determinants of the “unhealthy” phenotypes in our cohort.Conclusions: The “metabolically obese phenotype” is associated with bodyweight variability, multiple cardiometabolic abnormalities and an excess of central relative to peripheral fat in postmenopausal women. DXA‐derived centrality ratios can discriminate effectively between metabolic subtypes of obesity in menopause.
Variations between obese latinos and whites in weight‐related counseling during preventive clinical visits in the United States
Authors: Ma Jun , Xiao Lan , Yank Veronica 
Published: January 2013

ObjectiveTo examine rate differences and explanatory factors for lifestyle counseling to obese Latinos versus non‐Hispanic whites (NHWs) in U.S. outpatient settings.Design and MethodsThe 2009 National Ambulatory Medical Care Survey data assessed the provision of weight‐related lifestyle counseling during general medical exam visits (n = 688) by obese Latino and NHW adults. The Blinder‐Oaxaca decomposition technique to identify the fraction of the overall ethnic difference in counseling rate explained by a selection of measured variables based on the Anderson‐Newman‐Aday behavioral model were used.ResultsAlthough weight‐related lifestyle counseling rates were low in both ethnic groups, the rate among obese Latinos (51.3%) was significantly higher than among NHWs (35.8%) (P = 0.03), with 60% of the difference explained by observed factors. Enabling factors such as provider specialty, metropolitan statistical area, practice type, and provider employment type contributed the most to higher counseling rates among Latinos, whereas geographic region, continuity of care, and health insurance were enabling factors that, along with the predisposing factor of sex, contributed the most in the opposite direction.ConclusionsObese Latinos are more likely to receive weight‐related counseling during general medical exams than do NHWs, which is partly explained by physician practice and patient factors.
Calorie anticipation alters food intake after low‐caloric not high‐caloric preloads
Authors: Hogenkamp P.S. , Cedernaes J. , Chapman C.D. , Vogel H. , Hjorth O.C. , Zarei S. , Lundberg L.S. , Brooks S.J. , Dickson S.L. , Benedict C. , Schiöth H.B. 
Published: January 2013

ObjectiveCognitive factors and anticipation are known to influence food intake. The current study examined the effect of anticipation and actual consumption of food on hormone (ghrelin, cortisol, and insulin) and glucose levels, appetite and ad libitum intake, to assess whether changes in hormone levels might explain the predicted differences in subsequent food intake.Design and MethodsDuring four breakfast sessions, participants consumed a yogurt preload that was either low caloric (LC: 180 kcal/300 g) or high caloric (HC: 530 kcal/300 g) and was provided with either consistent or inconsistent calorie information (i.e., stating the caloric content of the preload was low or high). Appetite ratings and hormone and glucose levels were measured at baseline (t = 0), after providing the calorie information about the preload (t = 20), after consumption of the preload (t = 40), and just before ad libitum intake (t = 60).ResultsAd libitum intake was lower after HC preloads (as compared to LC preloads; P < 0.01). Intake after LC preloads was higher when provided with (consistent) LC information (467±254 kcal) as compared to (inconsistent) HC information (346±210 kcal), but intake after the HC preloads did not depend on the information provided (LC information: 290±178 kcal, HC information: 333±179 kcal; caloric load*information P = 0.03). Hormone levels did not respond in an anticipatory manner, and the post‐prandial responses depended on actual calories consumed.ConclusionsThese results suggest that both cognitive and physiological information determine food intake. When actual caloric intake was sufficient to produce physiological satiety, cognitive factors played no role; however, when physiological satiety was limited, cognitively induced satiety reduced intake to comparable levels.
Polyester resins with carbazole ring
Authors: Lubczak Renata 
Published: January 2013

Abstract3‐(9‐Carbazolyl)propane‐1,2‐diol was obtained in the reaction of 9‐(2,3‐epoxypropyl)carbazole with water. The obtained diol was further used for modification of unsaturated polyester resin to produce enhanced thermal and heat resistance in comparison with classic resins. The properties of polyesters and polyester resins modified with 3‐(9‐carbazolyl)propane‐1,2‐diol were studied in detail. When 3‐(9‐carbazolyl)propane‐1,2‐diol is used instead of propylene glycol the unsaturated polyester resins possess enhanced thermal stability.© 2013 Society of Chemical Industry
Controlled release of bovine serum albumin from stimuli‐sensitive silk sericin based interpenetrating polymer network hydrogels
Authors: Wu Wen , Wang Dongsheng , Lian Yuan 
Published: January 2013

AbstractIn recent years, the use of stimuli‐sensitive interpenetrating polymer network (IPN) hydrogels for the encapsulation and controlled release of protein drugs has received significant attention. The purpose of the present study was to investigate the release of bovine serum albumin (BSA), a model drug, from a series of thermosensitive silk sericin (SS) poly(N‐isopropylacrylamide) and pH‐responsive SS poly(methacrylic acid) IPN hydrogels. The effect of the chemical architecture of the IPN was investigated on the percentage loading of BSA and its subsequent release from the loaded devices. The temperature and pH of the release medium were studied for their impact on the release of BSA. The pulsatile releasing behavior of IPN hydrogels revealed that they can be made into microcapsules or thermo‐valves, which act as an on–off release control. © 2013 Society of Chemical Industry
Chemische Reaktionen in Superzeitlupe
Authors: Moshammer Robert , Rudenko Artem , Ullrich Joachim 
Published: January 2013

AbstractEinen neuen Weg in die Femtochemie eröffnen die intensiven Femtosekunden‐Lichtpulse im extremen Ultraviolett (EUV) aus dem Freie‐Elektronen‐Laser in Hamburg (FLASH) zusammen mit einer ausgefeilten Pump‐Probe‐Apparatur. Damit konnte erstmals die lichtinduzierte Umwandlung eines Acetylenmoleküls in sein Isomer Vinyliden in drei Dimensionen als “Zeitlupenfilm” visualisiert werden. Ein EUV‐Puls ionisiert zunächst das Acetylen, das seine Kernbausteine umordnet und allmählich die Form von Vinyliden annimmt. Ein zweiter, sehr intensiver Lichtpuls ionisiert es währenddessen weiter, so dass es explodiert. Aus der präzisen Erfassung der Fragmente gelingt eine genaue Rekonstruktion der geometrischen Struktur des Moleküls zum Explosionszeitpunkt. Der Ablauf dieser Isomerisierungsreaktion lässt sich durch Variation des Zeitabstands zwischen Pump‐ und Probepuls in Raum und Zeit präzise verfolgen. In Zukunft sollen damit chemische Reaktionen mit Femtosekunden‐Auflösung “gefilmt” werden, die für Biologie und Anwendungen wichtig sind.
Prickelnde Säfte – thermodynamische Sensorik
Authors: Vilgis Thomas 
Published: January 2013

Abstract“Kohlensäure” gibt Mineralwässern oder Champagner das Prickeln als gewisses Etwas. Aber auch kulinarisch lässt sich mit Kohlendioxid ordentlich “würzen”, vor allem wenn Temperatur und Druck stimmen. Mit Kohlendioxid versetzte kalte Gemüse‐ oder Kräutersäfte lassen sich eiskalt perfekt als Ergänzung in der Gastronomie einsetzen.
Self‐efficacy for coping with cancer in melanoma patients: its association with physical fatigue and depression
Authors: Albrecht Karoline , Droll Hannah , Giesler Jürgen M. , Nashan Dorothee , Meiss Frank , Reuter Katrin 
Published: January 2013

AbstractObjectiveThe purpose of this study was to explore the impact of self‐efficacy for coping with cancer (SECC) on physical fatigue and depressive symptoms in melanoma patients, in comparison with objective factors, such as treatment with interferon‐alpha (IFN‐α) and medical and sociodemographic variables. Current literature shows that psychological distress in melanoma patients is generally moderate, that they experience high quality of life, and that symptoms of depression and fatigue have been mostly associated with adjuvant IFN‐α treatmentMethodsA total of 175 melanoma patients, stages Ib–IIIc with and without low‐dose IFN‐α therapy, completed surveys on SECC, depression, and fatigue. Two hierarchical regression analyses were conducted to explore the predictive role of objective factors (first step: tumor stage, time since diagnosis, and current IFN‐α treatment; second step: age and gender) in conjunction with the subjective factor of SECC (third step) on physical fatigue and depression.ResultsRegression analysis revealed no significant effect of IFN‐α treatment upon depression. Current IFN‐α treatment was predictive of higher fatigue scores, however. The highest predictive effect by far was obtained for SECC, indicating higher fatigue and depression in patients with lower SECC.ConclusionsThe findings suggest that the treatment with IFN‐α is mainly accompanied by physical fatigue in melanoma patients rather than by mood changes. Most notably, the potential influence of increased SECC on reducing both physical fatigue and depression is suggested by the data, indicating the importance of self‐efficacy enhancing interventions in the psycho‐oncological support of melanoma patients. Copyright © 2013 John Wiley & Sons, Ltd.
A host‐plant‐derived volatile blend to attract the apple blossom weevil Anthonomus pomorum – the essential volatiles include a repellent constituent
Authors: Collatz Jana , Dorn Silvia 
Published: January 2013

AbstractBackgroundPlant volatiles are promising cues for trapping pest insects. This study started with a recently identified complex blend released by prebloom apple trees and aimed to reduce the number of compounds in the blend while maintaining the attraction of the target pest, the apple blossom weevil Anthonomus pomorum. An evaluation was made to determine whether attraction to plant volatiles is a general feature in this species.ResultsLaboratory‐based bioassays with field‐collected weevils demonstrated repellency by volatiles from the non‐host walnut, indicating that preference for plant odours is not a general feature in this species. By a subtractive bioassay approach, the original number of compounds in the apple‐plant‐released blend was stepwise reduced from 12 to 6 while maintaining weevil attraction. This resulting blend was as attractive as the full blend and as a blossom‐bud‐carrying apple twig. It was found to be composed of two synergistically interacting constituents, of which the first containing benzenoids was behaviourally inactive, and the second comprising the remaining compounds was even repellent.ConclusionsThis study enhances knowledge of the interaction of behaviourally effective constituents in complex odour blends and contributes to the development of an efficient monitoring system involving plant volatiles for the apple blossom weevil. © 2013 Society of Chemical Industry
In search of new herbicidal inhibitors of the non‐mevalonate pathway
Authors: Witschel Matthias , Röhl Franz , Niggeweg Ricarda , Newton Trevor 
Published: January 2013

AbstractThe first five steps of the non‐mevalonate pathway have been tested in high‐throughput screening (HTS) campaigns, using enzymes of plant origin. Hit rates were in general relatively low, which could be attributed to the high polarity and charged nature of substrates and active sites of these enzymes. Still, for all the enzymes, apart from IspF (2‐methylerythritol 2,4‐cyclodiphosphate synthase), inhibitors could be identified with activities below 100 μM, and these were followed up to identify structure–activity relationships (SARs). For the enzyme IspD (2C‐methyl‐D‐erythritol 4‐phosphate cytidyltransferase), inhibitors with IC50 down to 35 nM were identified that also showed herbicidal activity.
Impact of different ozone sounding networks on a 4D‐Var stratospheric data assimilation system
Authors: Baier F. , Erbertseder T. , Elbern H. , Schwinger J. 
Published: January 2013

AbstractObserving system simulation experiments (OSSEs) are performed to examine the impact of ozonesonde observations on a data assimilation system during a simulated satellite data gap during February 2003. Using the four‐dimensional variational chemical data assimilation system SACADA, the relative influence of launch rates and station coverage is investigated. Starting with the VINTERSOL/MATCH campaign, different network and sounding configurations are evaluated. To quantify the performance of assimilation experiments in the lower stratosphere, analysis skill and linear pattern correlation with respect to ERA‐Interim reference data are assessed for the 20 km altitude level. Using first‐guess and analysis minus observation error statistics,a priorierror settings are tuned to optimise the assimilation of simulated and real‐world ozone soundings. In summary, it is found that, during satellite data gaps, ozonesonde data can have a significant positive impact on the mean analysis skill depending both on the number of observations and the network layout. A better distributed network based on the GAW system, with 28 stations and three soundings bi‐weekly, proves clearly superior to VINTERSOL/MATCH, showing a positive gain in skill of 0.26 compared to a free‐running model.