bluuebunny/crossref_metadata_2025_split huggingface dataset:
EFL Learners’ Translation Strategies: A Semantic Bridge in Two Languages
Authors: Jupri Jupri , Rahman Arif , Hassan Ahmad Javed , Manu Said Malika Tridane 
Published: August 2024

This study examines translation strategies and the impact of translation strategies on translated texts produced by master's students of the English program at the campus of UNDIKMA Mataram. This study used a qualitative approach that included recording methods, specifically internal data recording. The data collected were 10 products translated from English to Indonesian by the requester. The English translation includes 390 words. They are allowed to use traditional or offline/electronic dictionaries when translating text. The study used several translation strategies, which are translation methods (literal translation and oblique translation) and translation processes (borrowing, calque translation, literal translation, modulation, transposition, equivalence, and translation). Transform). The results show that master's students tend to use local strategies and literal translation methods in translation. This affects the quality of the translation, making it less natural in the target language. In addition, translation errors also occur due to wrong/incorrect word selection, leading to failure to convey the message in the text source. The result of this research expected will bring valuable contributions to future research and courses serving translation activities.
Penerapan Nilai-Nilai Pendidikan Agama Islam dalam Meningkatkan Kedisiplinan Melalui Program Bimbingan dan Konseling di SMK Sultan Agung 1 Tebuireng
Authors: Izzatul Ma'rifah  , Syamsuddin  
Published: August 2024

Penerapan nilai-nilai PAI menanamkan akidah, ibadah, dan akhlak. Disiplin bagian penting dari kehidupan seperti aturan tentang memanfaatkan waktu dengan baik. Guru bimbingan dan konseling telah menanamkan disiplin kepada siswa serta memiliki pendekatan sesuai untuk mengatasi masalah kedisiplinan siswa. Fokus penelitian; 1). Bagaimana penerapan nilai- nilai PAI dalam meningkatkan kedisiplinan siswa di SMK Sultan Agung 1 Tebuireng, 2). Bagaimana penerapan nilai- nilai PAI dalam meningkatkan kedisiplinan siswa melalui program bimbingan dan konseling di SMK Sultan Agung 1 Tebuireng, 3). Apa saja faktor pendukungdan penghambat penerapan nilai- nilai PAI dalam meningktkan kedisiplinan siswa melalui program bimbingana dan konseiling di SMK Sultan Agung1 Tebuireng. Penelitian ini jenisnya adalah studi kasus, penelitian ini menggunakan pendekatan sebuah kualitatif, adapun pengumpulan data dengan observasi atau pengamatan, bertanya atau wawancara, serta dokumentasi. Hasil penelitiannya; 1). SMK Sultan Agung 1 Tebuireng menerapkan nilai-nilai PAI untuk meningkatkan kedisiplinan siswa dengan melewati berbagai tata tertib dan kegiatan keagamaan. Nilai Akidah; pemahaman tentang keyakinan dalam agama Islam. Nilai Ibadah; Siswa melaksanakan sholat berjama’ah dan praktik keagamaan lainnya. Nilai Akhlak; Penerapan tawadhu yang baik atau rasa hormat kepada yang lebih tua. 2). Nilai kedisiplinan; a). Disiplin Waktu, siswa tiba ke sekolah sesuai aturan sekolah, mengerjakan tugas tepat waktu. b). Disiplin Perbuatan, menerapkan aturan dan sanksi untuk memastikan kedisiplinan. Nilai bimbingan dan konseling meliputi; a). Bersikap Terbuka, Siswa merasa diperhatikan membuat mereka lebih menerima bimbingan dari guru bimbingan dan konseling. b). Humanistik, interaksi personal dengan siswa untuk memahami masalah mereka serta pemberian solusi. 3). Faktor pendukung dan penghambat tergantung latar belakang siswa, karena tingkat kedisiplinannya bermacam.
Hemodynamic influence of mild stenosis morphology in different coronary arteries: a computational fluid dynamic modelling study
Authors: Chen Xi , Cao Haoyao , Li Yiming , Chen Fei , Peng Yong , Zheng Tinghui , Chen Mao 
Published: August 2024

Introduction: Mild stenosis [degree of stenosis (DS) &lt; 50%] is commonly labeled as nonobstructive lesion. Some lesions remain stable for several years, while others precipitate acute coronary syndromes (ACS) rapidly. The causes of ACS and the factors leading to diverse clinical outcomes remain unclear.Method: This study aimed to investigate the hemodynamic influence of mild stenosis morphologies in different coronary arteries. The stenoses were modeled with different morphologies based on a healthy individual data. Computational fluid dynamics analysis was used to obtain hemodynamic characteristics, including flow waveforms, fractional flow reserve (FFR), flow streamlines, time-average wall shear stress (TAWSS), and oscillatory shear index (OSI).Results: Numerical simulation indicated significant hemodynamic differences among different DS and locations. In the 20%–30% range, significant large, low-velocity vortexes resulted in low TAWSS (&lt;4 dyne/cm2) around stenoses. In the 30%–50% range, high flow velocity due to lumen area reduction resulted in high TAWSS (&gt;40 dyne/cm2), rapidly expanding the high TAWSS area (averagely increased by 0.46 cm2) in left main artery and left anterior descending artery (LAD), where high OSI areas remained extensive (&gt;0.19 cm2).Discussion: While mild stenosis does not pose any immediate ischemic risk due to a FFR &gt; 0.95, 20%–50% stenosis requires attention and further subdivision based on location is essential. Rapid progression is a danger for lesions with 20%–30% DS near the stenoses and in the proximal LAD, while lesions with 30%–50% DS can cause plaque injury and rupture. These findings support clinical practice in early assessment, monitoring, and preventive treatment.
Lactic acid production by Lactobacillus casei using a sequence of seasonally available fruit wastes as sustainable carbon sources
Authors: Costa Stefania , Summa Daniela , Radice Matteo , Vertuani Silvia , Manfredini Stefano , Tamburini Elena 
Published: August 2024

Introduction: Lactic acid (LA) production from fossil resources is unsustainable owing to their depletion and environmental concerns. Thus, this study aimed to optimize the production of LA by Lactobacillus casei in a cultured medium containing fruit wastes (FWs) from agro-industries and second cheese whey (SCW) from dairy production, supplemented with maize steep liquor (MSL, 10% v/v) as the nitrogen source.Methods: The FWs were selected based on seasonal availability [early summer (early ripening peach), full summer (melon), late summer (pear), and early autumn (apple)] and SCW as annual waste. Small-scale preliminary tests as well as controlled fermenter experiments were performed to demonstrate the potential of using various food wastes as substrates for LA fermentation, except for apple pomace.Results and discussion: A 5-cycle repeated batch fermentation was conducted to optimize waste utilization and production, resulting in a total of 180.56 g/L of LA with a volumetric productivity of 0.88 g/L∙h. Subsequently, mechanical filtration and enzymatic hydrolysis were attempted. The total amount of LA produced in the 5-cycle repeated batch process was 397.1 g/L over 288 h, achieving a volumetric productivity of 1.32 g/L∙h. These findings suggest a promising biorefinery process for low-cost LA production from agri-food wastes.
Signatures of selection in Angus and Hanwoo beef cattle using imputed whole genome sequence data
Authors: Nawaz Muhammad Yasir , Savegnago Rodrigo Pelicioni , Lim Dajeong , Lee Seung Hwan , Gondro Cedric 
Published: August 2024

In this study, we detected signatures of selection in Hanwoo and Angus beef cattle using allele frequency and haplotype-based methods based on imputed whole genome sequence variants. Our dataset included 13,202 Angus animals with 10,057,633 imputed SNPs and 10,437 Hanwoo animals with 13,241,550 imputed SNPs. The dataset was subset down to 6,873,624 SNPs in common between the two populations to identify within population (runs of homozygosity, extended haplotype homozygosity) and between population signals of selection (allele fixation index, extended haplotype homozygosity). Assuming these selection signals were complementary to each other, they were combined into a decorrelated composite of multiple signals to identify regions under selection for each of the breeds. 27 genomic regions spanning 25.15 Mb and harboring 360 genes were identified in Angus on chromosomes 1,3, 4, 5, 6, 7, 8, 12, 13, 14, 16, 20, 21 and 28. Similarly, in Hanwoo, 59 genes and 17 genomic regions spanning 5.21 Mb on chromosomes 2, 4, 5, 6, 7, 8, 9, 10, 13, 17, 20 and 24 were identified. Apart from a small region on chromosome 13, there was no major overlap of selection signals between the two breeds reflecting their largely different selection histories, environmental challenges, breeding objectives and breed characteristics. Positional candidate genes identified in selected genomic regions in Angus have been previously associated with growth, immunity, reproductive development, feed efficiency and adaptation to environment while the candidate genes identified in Hanwoo included important genes regulating meat quality, fat deposition, cholesterol metabolism, lipid synthesis, neuronal development, and olfactory reception.
Elevated international normalized ratio contributes to poor prognosis in patients with traumatic lung injury
Authors: Lin Qingwei , Peng Enlan , Deng Xingping , Song Xiaomin , Zhong Lincui , He Longping , Zeng Qingbo , Song Jingchun 
Published: August 2024

ObjectiveTo investigate the pivotal determinants contributing to the adverse prognosis in patients afflicted with traumatic lung injury (TLI), with an aim to mitigate the elevated mortality rate associated with this condition.MethodsA retrospective analysis was carried out on 106 TLI patients who were admitted to the intensive care unit of a comprehensive hospital from March 2018 to November 2022. The patients were categorized into two groups based on their 28-day outcome: the survival group (n = 88) and the death group (n = 18). Random forest model, least absolute shrinkage and selection operator (LASSO) regression and support vector machine recursive feature elimination (SVM-RFE) were utilized to pinpoint the primary factors linked to poor prognosis in TLI patients. The Receiver Operating Characteristic (ROC) curve analysis was utilized to ascertain the predictive value of INR in forecasting the prognosis of TLI patients. Based on the cut-off value of INR, patients were categorized into two groups: INR ≥ 1.36 group (n = 35) and INR &lt; 1.36 group (n = 71). The 28-day survival rate was then compared using Kaplan–Meier analysis.ResultsRandom forest model, LASSO, and SVM-RFE jointly identified International standardization ratio (INR) as a risk factor for TLI patients. The area under the ROC curve for INR in predicting the 28-day mortality of TLI patients was 0.826 (95% CI 0.733–0.938), with a cut-off value of 1.36. The 28-day mortality risk for TLI patients with an INR ≥ 1.36 was 8.5 times higher than those with an INR &lt; 1.36.ConclusionTraumatic lung injury patients with elevated INR have a poor prognosis. An INR of ≥1.36 can be used as an early warning indicator for patients with traumatic lung injury.
Case report: Roxadustat overdose in an anemia patient of chronic kidney disease: insight beyond insignificant consequence
Authors: Zhang Long-Guang , Ma Xue-Juan , Li Xiang-Yang 
Published: August 2024

A 71-year-old man with a 20-year history of grade 3 hypertension experienced kidney dysfunction 2 years earlier. His serum creatinine (SCr) at the time was 140 μmol/L [with estimated glomerular filtration rate (eGFR) of 43.9 ml/min per 1.73m2], for which he received irbesartan since. At initial presentation, the spot urine dipstick protein was 1+, with an albumin-to-creatinine ratio of 230 mg/g (0–30) and normal urine sediments. The SCr was 176 μmol/L (eGFR = 32.8 ml/min per 1.73m2). The hemoglobulin (Hb) level decreased from 102 to 96 g/L despite oral ferrous succinate 100 mg twice daily starting 2 months ago. Roxadustat (ROXA) 50 mg (body weight, 70 kg) three times weekly was then prescribed. Unfortunately, the patient mistakenly took the drug at 50 mg three times a day (i.e., 1,050 mg instead of the intended 150 mg per week), which was 3.5 times the recommended starting dose for non-dialysis-dependent chronic kidney disease (CKD) patients (100 mg three times weekly for body weight &gt;60 kg) and two times the highest drug manual-recommended weekly dose (2.5 mg/kg three times weekly) approved in the country. When the attending nephrologist discovered the misuse 1 month later, the patient reported no apparent discomfort, and his home blood pressure was in the range 110–130/60–80 mmHg. Repeat blood tests showed that the Hb increased from 96 to 163 g/L and the SCr from 199 to 201 μmol/L in a month. The serum alanine transaminase (ALT) remained within the normal range (from 12 U/L at baseline to 20 U/L), while the serum total and indirect bilirubin levels were slightly elevated. ROXA was withheld immediately. In 30 days, the serum bilirubin returned to baseline, but the Hb decreased from 163 to 140 g/L, and then to 108 g/L after 3 months. On the other hand, the SCr increased from 179 to 203 μmol/L. At 9 months after the initial dosing, when the SCr increased to 256 μmol/L and the Hb decreased to 94 g/L again, ROXA 50 mg three times weekly was reinitiated uneventfully. Herein, by introducing a case who erroneously consumed twice the highest recommended dose of ROXA for a month, but had apparently no obvious discomfort or unfavorable consequence, we attempt to provide a brief overview of the mechanism of action, characteristics, drug metabolism, and side effect profile associated with this agent.
Dynamic A-to-I RNA editing during acute neuroinflammation in sepsis-associated encephalopathy
Authors: Li Yu-Ning , Liang Ya-Ping , Zhang Jing-Qian , Li Na , Wei Zhi-Yuan , Rao Yijian , Chen Jian-Huan , Jin Yun-Yun 
Published: August 2024

IntroductionThe activation of cerebral endothelial cells (CECs) has recently been reported to be the earliest acute neuroinflammation event in the CNS during sepsis-associated encephalopathy (SAE). Importantly, adenosine-to-inosine (A-to-I) RNA editing mediated by ADARs has been associated with SAE, yet its role in acute neuroinflammation in SAE remains unclear.MethodsOur current study systematically analyzed A-to-I RNA editing in cerebral vessels, cerebral endothelial cells (CECs), and microglia sampled during acute neuroinflammation after treatment in a lipopolysaccharide (LPS)-induced SAE mouse model.ResultsOur results showed dynamic A-to-I RNA editing activity changes in cerebral vessels during acute neuroinflammation. Differential A-to-I RNA editing (DRE) associated with acute neuroinflammation were identified in these tissue or cells, especially missense editing events such as S367G in antizyme inhibitor 1 (Azin1) and editing events in lincRNAs such as maternally expressed gene 3 (Meg3), AW112010, and macrophage M2 polarization regulator (Mm2pr). Importantly, geranylgeranyl diphosphate synthase 1 (Ggps1) and another three genes were differentially edited across cerebral vessels, CECs, and microglia. Notably, Spearman correlation analysis also revealed dramatic time-dependent DRE during acute neuroinflammation, especially in GTP cyclohydrolase1 (Gch1) and non-coding RNA activated by DNA damage (Norad), both with the editing level positively correlated with both post-LPS treatment time and edited gene expression in cerebral vessels and CECs.DiscussionThe findings in our current study demonstrate substantial A-to-I RNA editing changes during acute neuroinflammation in SAE, underlining its potential role in the disease.
The effect of proximity to grocery stores and the pandemic on parents’ and youths’ perceptions of eating habits in predominately African American rural communities
Authors: Williams Amanda , Newman Sharlene D. 
Published: August 2024

BackgroundRural communities have a disproportionately high level of childhood obesity along with high rates of food insecurity.ObjectivesTo assess the eating habits of youth in predominantly African American rural communities and assess the association between proximity to a grocery store and eating habits as well as how the COVID-19 pandemic may have impacted eating habits.Methods203 youth and parents completed a 16-item survey. Analyses were performed to assess the effect of having a neighborhood grocery store as well as to compare responses between youth and parents.ResultsHaving a neighborhood grocery store was associated with increased consumption of vegetables (F(1,122) = 41.56) and fruits (F(1,121) = 65.05), decreased consumption of chips (F(1,125) = 79.51) and a smaller percentage of overweight youth (χ2(1,125) = 5.03). Parents underestimated the effect of the COVID-19 pandemic on youth eating habits (χ2 (1,198) = 17.88).ConclusionProximity to a grocery store significantly associated with eating habits and weight in the rural communities examined. Given the steady decrease in the number rural grocery stores over the past decade it is important to consider how to improve access to healthy foods in these communities.
The moderating effect of perceived hope in the relationship between anxiety and posttraumatic growth during the Russian-Ukrainian war
Authors: Slezackova Alena , Malatincova Tatiana , Millova Katarina , Svetlak Miroslav , Krafft Andreas M. 
Published: August 2024

IntroductionThis study examines the relationships between perceived hope, posttraumatic growth, well-being, anxiety, and perceived threat of the Russian-Ukrainian War (RUW) in the Czech adult population. Drawing on the evidence of posttraumatic growth (PTG) amidst crisis, we hypothesized that perceived hope moderates the effects of perceived threat of war and anxiety on PTG.MethodsData were obtained from 1,000 Czech respondents via an online questionnaire ten months post-invasion. The form included measures of posttraumatic growth, perceived hope, well-being, anxiety and depression, and perceived threat of war.ResultsOur findings reveal that perceived hope acted as a moderator enhancing the positive effects of perceived threat and anxiety on PTG. However, perceived hope did not significantly moderate the direct effects of perceived threats and anxiety on well-being.DiscussionThis study highlights the significant role of hope amidst adversity and underscores its potential as a target for interventions aiming to foster PTG in populations who navigate traumatic experiences. Furthermore, it advocates for continued exploration of the factors interacting to enhance well-being and facilitate PTG in affected communities.
A bibliometric analysis of anxiety and depression among primary school students
Authors: Fu Jian Nan , Yu Wen Bing , Li Shuo Qi , Sun Wen Ze 
Published: August 2024

BackgroundRising anxiety and depression in primary school students adversely affect their development and academics, burdening families and schools. This trend necessitates urgent, focused research within this young demographic. This alarming trend calls for a systematic bibliometric analysis to develop effective preventative and remedial strategiesObjectivesThis study aims to identify and analyze the prevailing research hotspots and emerging trends concerning anxiety and depression in primary school students, thereby furnishing a foundational reference for future academic endeavors in this area.MethodsThis study uses the Web of Science (WOS) Core Collection database as the data source, focusing on literature published between 2013 and 2023 concerning anxiety and depression in primary school students. An initial search identified 1852 articles, which were then manually screened to exclude duplicates, conferences, announcements, and unrelated literature, resulting in 1791 relevant articles. The analysis, executed on December 31, 2023, employed CiteSpace and Vosviewer tools to assess various bibliometric indicators including authorship, country, institutional affiliations, publication trends, keyword frequency, and citation analysis.ResultsThe analysis revealed a corpus of 1,791 English-language articles, with a discernible upward trend in publications over the decade. The USA and China were the leading countries in this field, with 482and 272 papers, respectively. The research predominantly addresses the etiological factors of anxiety and depression, various intervention strategies, and the comorbidities associated with these conditions in the target population. Key research focuses have been identified in areas such as suicidal thoughts, bullying in schools, the impact of COVID-19, mindfulness interventions, and anxiety related to mathematics. Future research is projected to increasingly focus on the effects of mathematics anxiety on the psychological and behavioral outcomes in students.ConclusionThis study provides a critical visual and analytical overview of the key research areas and trends in the field of anxiety and depression among primary school students. It underscores the necessity of concentrating on the underlying causes and potential interventions. Such focused research is imperative for mitigating the mental health challenges faced by young students and enhancing their educational and developmental outcomes.
Can physical activity counteract the negative effects of sedentary behavior on the physical and mental health of children and adolescents? A narrative review
Authors: Wang Kun , Li Yan , Liu Hengxu , Zhang Tingran , Luo Jiong 
Published: August 2024

BackgroundThe increase in sedentary behavior (SB) in children and adolescents is one of the major threats to global public health, and the relationship between physical activity (PA) and SB has always been a key topic.MethodsThe literature search was conducted through PubMed, Web of Science, CNKI, Wanfang, and Scopus, and 121 pieces of literature were included in this study after screening and evaluation.Results(1) SB caused by screen time such as mobile phones and TVs has varying degrees of negative impact on obesity, cardiovascular metabolism, skeletal muscle development, and cognitive, and psychological disorders in children and adolescents. (2) Regular physical activity could effectively prevent, offset, or improve the harm of SB to the physical and mental health of children and adolescents, mainly by reducing the incidence of obesity, and cardiovascular and metabolic risks, promoting skeletal muscle development, and improving cognitive function and mental health. (3) The mechanism of physical activity to prevent or ameliorate the harm of SB was relatively complex, mainly involving the inhibition or activation of neurobiomolecules, the improvement of blood and cell metabolic factors, and the enhancement of brain functional connectivity.ConclusionsChildren and adolescents should avoid excessive SB, and through a variety of moderate to vigorous physical activity (MVPA) to replace or intermittent SB, which could effectively prevent or improve the harm of SB to physical and mental health.