bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multiresidue Pesticide Analysis of Tuber and Root Commodities by QuEChERS Extraction and Ultra-Performance Liquid Chromatography Coupled to Tandem Mass Spectrometry
Authors: Frenich Antonia Garrido , Fernández María Del Mar Martín , Moreno Laura Díaz , Vidal Jose Lúis Martínez , López-Gutiérrez Noelia 
Published: October 2012

Abstract
A simple, rapid, and reliable multiresidue method to determine 84 pesticides in potato and carrot samples by ultra-performance liquid chromatography coupled to MS/MS has been developed and fully validated for routine analysis according to ISO/IEC 17025:2005. The method makes use of a buffered Quick, Easy, Cheap, Effective, Rugged, and Safe (QuEChERS) sample preparation procedure based on a single extraction with acidified acetonitrile, followed by partitioning with salts. Chromatographic conditions were optimized in order to achieve a rapid separation in the multiple reaction monitoring mode. Performance characteristics of the method, including an estimation of measurement uncertainty using validation data, are reported for both matrixes. Calibration curves were linear from 0.010 to 0.150 mg/kg for most compounds. The LOD and LOQ were 0.006 and 0.010 mg/kg, respectively, except for fluorocloridone, fluquinconazol, and hexitiazox, which were 0.030 and 0.050 mg/kg, respectively. Recoveries obtained were in the range 70–116%, with intraday precision values ≤20% RSD and interday precision values ≤25% RSD at two different concentration levels. The overall uncertainty of the method was estimated at two concentrations as being lower than 34% in all cases. The method has been applied to the analysis of 70 vegetable samples, and imidacloprid and linuron were the pesticides most frequently found in potato and carrot commodities, respectively.
Razões para a falta de rendimento esportivo do Comercial F.C.
Authors: Ferraresi de Araujo Gerado José , Costa André Lucirton , Carvalho Cesar Machado 
Published: October 2012

The international football, according to the report of the Plan for Modernization of the Brazilian Football FGV (2000) annual turnover of approximately $ 250 billion, while Brazil represents only 1% of the total. The Commercial F. C. headquartered in the city of Ribeirão Preto (SP), had its poly auctioned sports stadium partially forbidden for 23 years and not disputed the series A1, A3series being relegated to the Campeonato Paulista in 2009. This study aimed to identify those factors that hinder sports performance of the Commercial F. C., to do so, we studied its history, its relations with the government and legislation, market performance, partnerships established, administrative structures and results in the tournaments played between 2007 and 2008 to discuss their management problems. The methods used were research-explanatory and qualitative semi-structured interview to build a case study. We conclude that the gap between the formal structure and practice of members of the answers as a key element in the absence of the club's sports performance.
Faire confiance au Canadien moyen – Les manuels techniques de Louis-Alexandre Bélisle
Authors: Vincent Josée 
Published: October 2012

C’est à la veille de la Deuxième Guerre mondiale que Louis-Alexandre Bélisle, journaliste et enseignant devenu imprimeur, conçoit plusieurs collections de manuels à l’usage des ouvriers et des élèves des écoles techniques. Inspirée en partie d’ouvrages produits aux États-Unis, la série « Arts, métiers et technique » n’en est pas moins collée à la réalité québécoise. En effet, Bélisle ne se contente pas de transposer des données factuelles dans le contexte canadien, il adapte les contenus et, surtout, il accorde une importance capitale à la terminologie, n’hésitant pas à conserver des anglicismes et à avoir recours à des canadianismes pour mieux rendre compte de l’univers ouvrier. Ainsi, avec ses manuels, non seulement Bélisle reconnaît l’originalité et l’exactitude du vocabulaire ouvrier, mais il en revendique l’utilisation et en défend la légitimité. Les manuels de Bélisle s’adressent à une classe ouvrière économiquement et culturellement dominée. Certes, l’éditeur y transpose sa vision du monde, soit celle d’un enseignant de l’École de commerce et d’un patron d’entreprise, mais il y transmet aussi sa conception de la culture, qui lui fait préférer au français standard la vivacité de la langue du peuple. C’est cet intérêt pour la langue qui fait des manuels de Bélisle un cas à part, à la frontière des cultures bourgeoise et ouvrière.
Attention-Deficit/Hyperactivity Disorder Diagnoses in Finland During the COVID-19 Pandemic
Authors: Auro Kirsi , Holopainen Ida , Perola Markus , Havulinna Aki S. , Raevuori Anu 
Published: June 2024

ImportanceSeveral reports suggest an increase in attention-deficit/hyperactivity disorder (ADHD) symptoms during the COVID-19 pandemic. This nationwide study assessed new ADHD diagnoses and ADHD prevalence before and during the pandemic.ObjectiveTo investigate trends in new ADHD diagnoses, prevalence, and ADHD medication use from 2015 to 2022 in Finland.Design, Setting, and ParticipantsThis longitudinal cohort study comprised the entire Finnish population. ADHD diagnoses and medication use were obtained from nationwide registers and assessed at 3 time points: in 2015 and before (2020) and after (2022) the pandemic. Data were analyzed from January 2015 to June 2022.Main outcomes and MeasuresNew ADHD diagnoses, ADHD lifetime prevalence, and ADHD medication use.ResultsThe cohort comprised 5 572 420 individuals (2 819 645 women [50.6%]). Lifetime prevalence of ADHD increased by 2.7-fold during 2015 to 2022; prevalence was 1.02% in 2015 (95% CI, 1.01%-1.03%), 1.80% in 2020 (95% CI, 1.79%-1.81%), and 2.76% in 2022 (95% CI, 2.75%-2.77%). Young men aged 13 to 20 years had the highest lifetime prevalence of 11.68% (95% CI, 11.56%-11.81%) in 2022. New ADHD diagnoses doubled during the pandemic, from 238 per 100 000 in 2020 to 477 per 100 000 in 2022. The pandemic-associated incremental increase in new diagnoses was 18.60% (95% CI, 16.47%-20.49%; 9482 per 50 897 cases). Young women aged 13 to 20 years had a 2.6-fold increase in new diagnoses during the pandemic, from 577 per 100 000 in 2020 to 1488 per 100 000 in 2022, and women aged 21 to 30 years had a 3.0-fold increase, from 361 per 100 000 to 1100 per 100 000. New diagnoses increased by 2.9-fold among those older than 55 years (from 5 per 100 000 to 13 per 100 000 in women and from 5 per 100 000 to 14 per 100 000 in men). Boys younger than 13 years had the highest absolute rate of new ADHD diagnoses in 2022 (1745 per 100 000), but boys and young men younger than 21 years did not show a significant incremental increase in new diagnoses. Lifetime prevalence of ADHD medication purchases was 0.57% (95% CI, 0.56%-0.58%) in 2015 (31 771 [55.62%] of those with ADHD diagnosis), 1.15% (95% CI, 1.14%-1.16%) in 2020 (64 034 [63.83%]), and 1.69% (95% CI 1.68%-1.70%) in 2022 (92 557 [61.43%]), respectively.Conclusions and RelevanceIn this nationwide cohort study, new ADHD diagnoses and ADHD prevalence showed significant increase in Finland during the pandemic. ADHD medication use did not increase in relation to ADHD diagnoses. These results highlight potential adverse outcomes of pandemic-associated changes in living conditions.
Electrochemical Liquid‐Liquid‐Solid Growth of Ag‐In Crystals with Liquid Indium Alloy Electrodes
Authors: Wu Henry , Hazelnis Joshua P. , Maldonado Stephen 
Published: June 2024

AbstractSynthesis of intermetallic crystals by electrodeposition of Ag from alkaline aqueous electrolytes containing AgCN onto liquid metal electrodes via an electrochemical liquid‐liquid‐solid (ec‐LLS) process has been performed. X‐ray diffraction, scanning electron microscopy, and transmission electron microscopy were performed to identify crystalline products. Ec‐LLS experiments performed with pure liquid Hg and Ga electrodes resulted in the formation of polycrystalline Ag2Ga and Ag2Hg3. Experiments performed with In‐containing liquid metals preferentially yielded Ag9In4 and AgIn2 products with liquid Hg0.35In0.65 and Ga0.86In0.14, respectively. The product distribution with liquid Hg0.35In0.65 depended on the level of Ag supersaturation during the electrodeposition. A mechanism that accounts for the aforementioned observations is presented and discussed. This work described the formation of Ag−In intermetallic phases by the isothermal electroreduction of Ag into different liquid metal solvents via ec‐LLS. Electrodeposition of Ag into a pure Ga or pure Hg liquid metal pool yielded precisely the compounds predicted from isothermal cross‐sections of the respective binary phase diagrams. These compounds were not found when using liquid Hg or Ga containing appreciable In. The smaller enthalpy of formation for AgIn2 was consistent with its synthesis in Ga0.86In0.14. However, the observed product of Ag9In4 in Hg‐containing liquid metals could not be rationalized solely from thermodynamic factors. Instead, this observation was consistent with a kinetic pathway based on the lability of Hg‐metal bonds and nearly identical crystal structures of Ag9In4 and Ag2Hg3. Site exchange of Hg for In is consistent with our prior observations[23] of In exchange into Hg−Pd structures during Pd electrodeposition. This mechanism is not based on any direct role of electrochemistry other than aspects that dictate the operative supersaturation of the metal solute.
Hollow CeO2‐Based Nanozyme with Self‐Accelerated Cascade Reactions for Combined Tumor Therapy
Authors: Meng Lili , Tang Lingxue , Gao Fangli , Zhu Liang , Liu Xinhe , Zhang Jie , Chang Yi , Ma Xiaoming , Guo Yuming 
Published: June 2024

AbstractNanozymes have obvious advantages in improving the efficiency of cancer treatment. However, due to the lack of tissue specificity, low catalytic efficiency, and so on, their clinical applications are limited. Herein, the nanoplatform CeO2@ICG@GOx@HA (CIGH) with self‐accelerated cascade reactions is constructed. The as‐prepared nanozyme shows the superior oxidase (OXD)‐like, superoxide dismutase (SOD)‐like, catalase (CAT)‐like and peroxidase (POD)‐like activities. At the same time, under 808 nm near‐infrared (NIR) irradiation, the photodynamic and photothermal capabilities are also significantly enhanced due to the presence of indocyanine green (ICG). We demonstrate that the nanozyme CIGH can efficiently accumulate in the tumor and exhibit amplified cascade antitumor effects with negligible systemic toxicity through the combination of photodynamic therapy (PDT), photothermal therapy (PTT), chemodynamic therapy (CDT) and starvation therapy. The nanozyme prepared in this study provides a promising candidate for catalytic nanomedicines for efficient tumor therapy.
Doping control of estra‐4,9‐diene‐3,17‐dione in horses
Authors: Ho Helen S. M. , Farrington Adrian F. , Bond Amanda J. , Ho Emmie N. M. , Wong Wing‐Tak 
Published: June 2024

AbstractEstra‐4,9‐diene‐3,17‐dione (dienedione) is an anabolic‐androgenic steroid (AAS) available on the market as a dietary supplement for bodybuilding. It is prohibited in both human and equine sports due to its potential performance‐enhancing effect. With the rare presence of the 4,9‐diene configuration in endogenous steroids, dienedione has been considered as a synthetic AAS. Nevertheless, the reoccurring detection of dienedione in entire male horse urine samples led to the investigation of its possible endogenous nature in horses, and its endogenous nature in entire male horses has been recently confirmed and reported by the authors' laboratory. While dienedione is not detected in castrated horses (geldings), it is essential to study its elimination and identify its metabolites for its effective control. To study the elimination and biotransformation of dienedione, administration experiments were performed by giving three castrated horses (geldings) each single oral dose of 1500 mg of dienedione powder for seven consecutive days. The postulated in vivo metabolites included 17‐hydroxyestra‐4,9‐dien‐3‐one (M1a and M1b), hydroxylated dienedione (M2a, M2b, M3a, M3b, M4, M5) and hydroxylated M1 (M6a, M6b, M7a, M7b, M8a and M8b), formed from hydroxylation and reduction of dienedione. To control the misuse of dienedione in geldings, M3a and M3b are the potential targets that gave the longest detection time, which could be detected for up to 2–5 days in urine and 0.4–4 days in plasma.
Therapeutic plasmapheresis in idiopathic membranous nephropathy anti‐PLA2R‐related: A case series
Authors: Musone Dario , Nicosia Valentina , D'Alessandro Riccardo , Andrietti Marco , Steri Paolo Francesco , Ruosi Carolina , Giuliana Sofia , Elefante Claudia , Cuccurullo Pina , Treglia Antonio 
Published: June 2024

AbstractMembranous nephropathy is the most common cause of nephrotic syndrome (NS) in non‐diabetic adults; in 80% of patients it is idiopathic (PMN). PMN has an autoimmune pathogenesis, 70%‐85% of patients have increased titer of antibodies to the podocyte membrane antigen PLA2R. The etiological, prognostic and predictive role of the Ab anti‐PLA2R is demonstrated. Standard therapy consists in anti‐CD20 monoclonal antibody rituximab (RTX) combined with steroids or immunosuppressants according to the risk of progressive loss of kidney function. The immunosuppressive therapies are potentially associated to severe adverse events that lead to protocol suspension. Given their pivotal pathogenetic role, serum clearance of anti‐PLA2R with plasmapheresis could have a beneficial impact on NS, particularly in patients not requiring or tolerating standard therapies. In this series, we present three cases of PMN anti‐PLA2R related treated with a RTX plus plasmapheresis approach and demonstrate its overall effective role on anti‐PLA2R titer and clinical outcomes.
Accelerating workforce development in the federal infrastructure moment and beyond
Authors: Kane Joseph W. 
Published: June 2024

AbstractA surge in US federal infrastructure funding is accelerating a variety of transportation, water, energy, broadband, and other improvements nationally, with the potential to support millions of new jobs. However, continued struggles to recruit, train, and retain infrastructure workers—particularly younger workers, women, and people of color—may limit the reach and ultimate impact of this funding. This article—drawing from past Brookings Institution analyses on the infrastructure workforce—explores these struggles in greater depth and points to several steps that both infrastructure and workforce leaders can take to better harness new funding and support more durable workforce development strategies in years to come.
Nutrient limitation dampens the response of a harmful algae to a marine heatwave in an upwelling system
Authors: Fischer Alexis D. , Houliez Emilie , Bill Brian D. , Kavanaugh Maria T. , Alin Simone R. , Collins Andrew U. , Kudela Raphael M. , Moore Stephanie K. 
Published: June 2024

AbstractHarmful algal blooms caused by toxin‐producing species of the diatom genus Pseudo‐nitzschia have been linked to anomalously warm ocean conditions in the Northern California Current System. This study compares summertime concentrations of Pseudo‐nitzschia spp. and the toxin they produce, domoic acid, during a marine heatwave year (2019) and a climatologically neutral year (2021). An Imaging FlowCytobot was installed on a fishery survey vessel alongside environmental sensors to continuously sample phytoplankton and oceanographic parameters. This was paired with targeted manual sample collections for nutrients, chlorophyll, and domoic acid. Accumulations of Pseudo‐nitzschia spp. were associated with upwelling zones and established hotspot regions: the Juan de Fuca Eddy, Heceta Bank, and Trinidad Head. Overall, however, Pseudo‐nitzschia spp. and domoic acid concentrations were low during both summers and appear to have been limited by nitrate. Nutrient availability may therefore modulate the response of Pseudo‐nitzschia spp. to warm anomalies. Comparison of these results with 2015, another marine heatwave year but one that produced record concentrations of Pseudo‐nitzschia spp. and domoic acid, suggests that the timing of marine heatwave conditions in the nearshore relative to seasonal upwelling plays a key role in determining whether a Pseudo‐nitzschia spp. harmful algal bloom will occur.
A linear finite difference scheme with error analysis designed to preserve the structure of the 2D Boussinesq paradigm equation
Authors: Poochinapan K. , Manorot P. , Mouktonglang T. , Wongsaijai B. 
Published: June 2024

AbstractUse of the finite difference method has produced successful solutions to the general partial differential equations due to its efficiency and effectiveness with wide applications. For example, the 2D Boussinesq paradigm equation can be numerically studied using a linear‐implicit finite difference scheme based on the Crank‐Nicolson/Adams‐Bashforth technique. First, conservative quantities are derived and preserved through numerical scheme. Then, the convergence and stability analysis is then provided to simulate a numerical solution whose existence and uniqueness are proved based on the boundedness of the numerical solution. Analysis of spatial accuracy is found to be second order on a uniform grid. Numerical results from simulations indicate that these proposed scheme provide satisfactory second‐order accuracy both in time and space with an ‐norm, and also preserve discrete invariants. Additionally, previous scientific literature review has provided little evidence of studied terms with dispersive effect in 2D Boussinesq paradigm equation. The current study explores solution behavior by applying the proposed scheme to numerically analyze initial Gaussian condition.
Zoonoses in the workplace: A Seroprevalence study of Coxiella, Brucella, and Leptospira among marine mammal rescue and rehabilitation workers in California
Authors: Bjork Adam , Stoddard Robyn A. , Anderson Alicia D. , de Perio Marie A. , Niemeier Richard Todd , Self Joshua S. , Fitzpatrick Kelly A. , Gulland Frances M. D. , Field Cara L. , Kersh Gilbert J. , Gibbins John D. 
Published: June 2024

AbstractBackgroundQ fever, brucellosis, and leptospirosis are zoonoses typically associated with terrestrial animal reservoirs. These bacterial agents are now known to infect marine mammal species, though little is known about potential human health risks from marine mammal reservoir species. We investigated potential risks of these bacteria in humans associated with marine mammal exposure.MethodsThe Marine Mammal Center (TMMC) in Sausalito, California, requested a Health Hazard Evaluation by the National Institute for Occupational Safety and Health. In June 2011, an investigation occurred, which included a written questionnaire and serosurvey among workers for Coxiella burnetii, Brucella spp., and Leptospira spp., and an environmental assessment for C. burnetii.ResultsSerologic evidence of past exposure was detected in 4% (C. burnetii), 0% (Brucella), and 1% (Leptospira) of 213 participants, respectively. One of 130 environmental samples tested positive for C. burnetii. No significant marine mammal‐specific risk factors were identified, but some safety deficiencies were noted that could lead to a higher risk of exposure to zoonotic diseases.ConclusionAlthough this study did not identify disease exposure risks associated with marine mammals, additional studies in different settings of other groups with frequent exposure to marine mammals are warranted. Some deficiencies in safety were noted, and based on these, TMMC modified protocols to improve safety.
Prevalence of bacterial vaginosis among pregnant women attending antenatal care in low‐ and middle‐income countries between 2000 and 2020: A systematic review and meta‐analysis
Authors: Park Faith Jiyeong , Rosca Aliona S. , Cools Piet , Chico R. Matthew 
Published: June 2024

AbstractBackgroundBacterial vaginosis increases risk of preterm birth and low birthweight, adverse pregnancy outcomes that disproportionately affect low‐ and middle‐income countries (LMICs).ObjectivesWe aimed to estimate the prevalence of bacterial vaginosis among pregnant women attending antenatal care in LMICs between 2000 and 2020.Search StrategyWe conducted a systematic review of PubMed, Embase and five regional databases.Selection CriteriaWe included studies conducted in LMICs and published between 2000 and 2020 in which bacterial vaginosis prevalence was reported among pregnant women attending antenatal care.Data Collection and AnalysisWe corrected point estimates and applied random‐effects models to generate pool prevalence estimates. We carried out subgroup analyses by study year, country‐income level, HIV prevalence, sample size, diagnostic method, trimester of pregnancy, presence of symptoms at diagnosis and risk of bias.Main ResultsOf 1132 publications, 74 studies met inclusion criteria, contributing 80 data points from 46 661 pregnant women. Overall pooled mean prevalence across LMICs was 15.7%. Regional prevalence ranged from 25.1% in sub‐Saharan Africa to 7.4% in Central and Southern Asia. Prevalence was 33.4% in studies where HIV prevalence was ≥10%, and 6.6% in which HIV prevalence was <10%. The prevalence of bacterial vaginosis among pregnant women who were symptomatic was 24.2% versus 11.8% among those without associated symptoms.ConclusionsBacterial vaginosis prevalence is high. World Health Organization guidelines recommend screening and treatment for symptomatic pregnant women. This recommendation should be extended to include all pregnant women who have HIV infection. Research is needed to characterise biological mechanisms of bacterial vaginosis that lead to preterm birth and low birthweight, and to investigate antenatal interventions that may better interrupt these pathways.
39‐1: Invited Paper: RGB Nanowire Based Micro‐LED Chips For Efficient and High Performance Ultra Fine Pitch Direct View Displays
Authors: Robin Ivan-Christophe , Tchoulfian Pierre , Sannicolo T. , Malier Yoann , Butaud Eric , Gilet Philippe 
Published: June 2024

One of the micro‐LED direct view display major challenges is to find ways of drastically dropping the cost, for instance, by reducing the micro‐LED size, simplifying the assembly process and improving the assembly yield.In this paper, we present Aledia's GaN‐on‐Si nanowire (NW) LED technology made on standard 8 “Si wafers, scalable to 12” wafers. We will present two components using our NW technology and their use case for the manufacturing of micro‐LED direct view fine pitch display:

NWs RGB three color chips obtained using quantum dot (QD) color conversion at chip level. The RGB chips can then be transferred on PCB or glass or TFT substrates for panel manufacturing.
The integration within the same chip of a three color RGB chip together with its CMOS driving electronics. Those chips allow to obtain an active‐matrix architecture on any passive backplane without the use of TFT.