bluuebunny/crossref_metadata_2025_split huggingface dataset:
Retrospective analysis of the effect of SGLT-2 inhibitors on renal function in patients with type 2 diabetes in the real world
Authors: Song Rongjing , Hou Qiaoyu , Zhang Xiuying , Zhao Wei , Liu Gang , Li Meng , Zhang Xiaohong , Ji Linong 
Published: August 2024

IntroductionThe protective effect of sodium–glucose cotransporter-2 (SGLT-2) inhibitors on the kidneys has been widely recognized. However, limited research has reported the changes in estimated glomerular filtration rate (eGFR) of real-world patients with type 2 diabetes mellitus (T2DM) over time after administration of SGLT-2 inhibitors. This study aimed to reflect the trend of eGFR changes over time in T2DM patients having different baseline eGFR after SGLT-2 inhibitors administration in the real world.MethodsA single-center retrospective study was performed in a tertiary public hospital in Beijing, China. In total, 998 outpatients with T2DM who initiated SGLT-2 inhibitors treatment were included in the study. The changes in eGFR, urinary albumin/creatinine ratio (UACR), and glycolipid metabolism indicators were analyzed during the 18-month follow-up period.ResultsThe eGFR levels significantly decreased to their lowest point (−3.04 mL/min/1.73 m2) in the first 3 months after initiation of SGLT-2 inhibitors treatment, however, gradually returned to the baseline level after 1 year. Compared to the subgroup with eGFR &gt;90 mL/min/1.73 m2, improvements in renal function were more significant in patients with T2DM from the 60 &lt; eGFR ≤90 mL/min/1.73 m2 and eGFR ≤60 mL/min/1.73 m2 subgroups after treatment with SGLT-2 inhibitors. Similarly, SGLT-2 inhibitors reduced the UACR in patients with diabetic nephropathy.ConclusionThis study further confirmed the real-world long-term protective effect of SGLT-2 inhibitors on the kidneys of patients with T2DM, which is not related to baseline renal function and blood glucose.
Green synthesis of zinc oxide nanoparticles from Wodyetia bifurcata fruit peel extract: multifaceted potential in wound healing, antimicrobial, antioxidant, and anticancer applications
Authors: Moalwi Adel , Kamat Keerti , Muddapur Uday M. , Aldoah Bader , AlWadai Hajar Hassan , Alamri Abdulrahman Manaa , Alrashid Fauwaz Fahad , Alsareii Saeed Ali , Mahnashi Mater H. , Shaikh Ibrahim Ahmed , Khan Aejaz Abdullatif , More Sunil S. 
Published: August 2024

This study focuses on the synthesis, characterization, and use of zinc oxide nanoparticles (ZnONPs) derived from W. bifurcata fruit peel extract. ZnONPs are frequently synthesized utilizing a green technique that is both cost-effective and ecologically friendly. ZnONPs were characterized utilizing analytical techniques. Ultra Violet visible (UV-Vis) spectra showed peaks at 364 nm, confirming the production of ZnONPs. Scanning Electron Microscope analysis indicated that the nanoparticles generated were spherical/agglomerated, with diameters ranging from 11 to 25 nm. FTIR spectroscopy was used to identify the particular functional groups responsible for the nanoparticles’ reduction, stabilization, and capping. Phytochemical analysis of the extract revealed that flavonoids, saponins, steroids, triterpenoids, and resins were present. The antibacterial activity of W. bifurcata synthesised nanoparticles was evaluated against pathogenic bacteria. The ZnONPs antioxidant activity was assessed using DPPH assay. The in vitro cytotoxicity was assessed against prostate cancer PC3 cells. The wound healing potential was assessed by employing in vitro scratch assay and in vivo excision model in Wistar rats. Because of its environmentally benign production, low toxicity, and biocompatibility, ZnONPs exhibited potential antibacterial, antioxidant, anticancer, and wound healing activities, indicating that they could be used in cancer treatment and wound management. Further study is required to examine the fundamental mechanisms and evaluate the safety and effectiveness of the test sample in clinical situations.
The prevalence of sarcopenia and risk factors in the older adult in China: a systematic review and meta-analysis
Authors: Meng Shilong , He Xiaomin , Fu Xinlei , Zhang Xu , Tong Minghao , Li Wei , Zhang Wei , Shi Xiaolin , Liu Kang 
Published: August 2024

BackgroundUnderstanding the epidemiological information of a certain disease is the first step in related prevention and control work. This article aims to understand the prevalence and associated risk factors of sarcopenia among the older adult (≥60 years old) in China and to provide an evidence-based basis for early identification, management, and prevention of sarcopenia patients.MethodsWe searched seven databases: CNKI, Wanfang, VIP, PubMed, Web of Science, Embase, and Cochrane Library databases from the establishment of the database until January 31, 2024. The Quality evaluation criteria of cross-sectional studies recommended by the Agency for Healthcare Research and Quality (AHRQ) were used for literature quality evaluation. Stata 18.0 software was used for statistical analysis.ResultsWe finally included 45 studies, involving a total of 37,571 cases. After statistical analysis, we found that the prevalence of sarcopenia among the older adult in China was 20.7% [95% CI (18.3, 23.0%)]. The results of subgroup analysis suggest that: ① According to gender, the prevalence rate of sarcopenia in women (21.6%) is higher than that in men (19.2%); ② According to age, the prevalence rate of older adult people aged ≥80 (45.4%) was the highest, followed by 70–79 (27.2%) and 60–69 (15.7%). ③ According to region, the prevalence rate of the older adult in the south (21.7%) is higher than that in the north (19.0%); ④ According to the time of publication, the prevalence of sarcopenia among the older adult in China has increased (from 19.2% in 2014–2018 to 21.4% in 2019–2024); ⑤ According to the diagnostic criteria, the detection rate of AWGS (2019) is higher than that of AWGS (2014) (24.5% vs. 19.3%). Finally, aging, low BMI, low leg circumference, smoking, depression, osteoporosis, malnutrition and malnutrition risk are all risk factors for sarcopenia among the older adult in China.ConclusionThe prevalence of sarcopenia in the older adult in China was higher (20.7%), which should be paid attention to by relevant health authorities. In addition, aging, low BMI, low calf circumference, smoking, depression, osteoporosis, malnutrition and malnutrition risk are risk factors for the development of sarcopenia in the older adult in China. For these high-risk populations, early identification, prevention, and intervention can be carried out to delay the occurrence and progression of sarcopenia.
Assessment of patients’ knowledge and perceptions of MRI scans and safety in Saudi Arabia
Authors: Alghamdi Sami A. 
Published: August 2024

BackgroundThis study was conducted to assess the levels of knowledge about MRI scans and safety measures among patients in Saudi Arabia.MethodsThis cross-sectional study was conducted at nine Saudi Arabian hospitals and utilized a questionnaire comprising 22 items that evaluated patients’ knowledge regarding MRI scans and safety measures, divided into four sections. The questions encompassed patients’ sociodemographic data (A), knowledge about MRI (B), safety measures (C), and communication (D). Descriptive statistics were used to characterize the participant demographics and responses.ResultsOut of 446 MRI patients, 60.5% correctly identified that MRI does not involve ionizing radiation, and 78% recognized MRI as a diagnostic tool. Further, 94.2% knew that metal objects are not allowed in MRI rooms. However, 80.3% incorrectly believed that pregnant patients cannot undergo MRI at any time, 57% thought the MRI scanner is turned off when not in use, and 72.6% did not recognize any MRI-compatible devices. About 62% were unaware of the need for kidney function tests with contrast agents, and 43% reported anxiety during MRI scans. Overall, 57% of the patients had limited knowledge of MRI safety, with 39.5% considering their understanding adequate. Educational attainment and employment status were significantly associated with improved MRI knowledge. Most participants sought information from healthcare professionals.ConclusionThis study highlights the need to educate patients about MRI procedures and safety protocols. Significant gaps remain in patients’ knowledge, especially regarding safety measures. Higher levels of educational attainment and employment status were linked to greater levels of MRI knowledge, suggesting the importance of targeted educational interventions. Healthcare professionals were the patients’ main information sources; nevertheless, comprehensive and accessible information is necessary. Improved communication and training for healthcare providers can enhance patient understanding and experiences during MRI scans.
WATERHYPERNET: a prototype network of automated in situ measurements of hyperspectral water reflectance for satellite validation and water quality monitoring
Authors: Ruddick Kevin G. , Brando Vittorio E. , Corizzi Alexandre , Dogliotti Ana I. , Doxaran David , Goyens Clémence , Kuusk Joel , Vanhellemont Quinten , Vansteenwegen Dieter , Bialek Agnieszka , De Vis Pieter , Lavigne Héloise , Beck Matthew , Flight Kenneth , Gammaru Anabel , González Vilas Luis , Laizans Kaspars , Ortenzio Francesca , Perna Pablo , Piegari Estefania , Rubinstein Lucas , Sinclair Morven , Van der Zande Dimitry 
Published: August 2024

This paper describes a prototype network of automated in situ measurements of hyperspectral water reflectance suitable for satellite validation and water quality monitoring. Radiometric validation of satellite-derived water reflectance is essential to ensure that only reliable data, e.g., for estimating water quality parameters such as chlorophyll a concentration, reach end-users. Analysis of the differences between satellite and in situ water reflectance measurements, particularly unmasked outliers, can provide recommendations on where satellite data processing algorithms need to be improved. In a massively multi-mission context, including Newspace constellations, hyperspectral missions and missions with broad spectral bands not designed for “water colour”, the advantage of hyperspectral over multispectral in situ measurements is clear. Two hyperspectral measurement systems, PANTHYR (based on the mature TRIOS/RAMSES radiometer) and HYPSTAR® (a newly designed radiometer), have been integrated here in the WATERHYPERNET network with SI-traceable calibration and characterisation. The systems have common data acquisition protocol, data processing and quality control. The choice of validation site and viewing geometry and installation considerations are described in detail. Three demonstration cases are described: 1. PANTHYR data from two sites are used to validate Sentinel-2/MSI (A&amp;B); 2. HYPSTAR® data at six sites are used to validate Sentinel-3/OLCI (A&amp;B); 3. PANTHYR and HYPSTAR® data in Belgian North Sea waters are used to monitor phytoplankton parameters, including Phaeocystis globosa, over two 5 month periods. Conclusion are drawn regarding the quality of Sentinel-2/MSI and Sentinel-3/OLCI data, including indications where improvements could be made. For example, a positive bias (mean difference) is found for ACOLITE_DSF processing of Sentinel-2 in clear waters (Acqua Alta) and clues are provided on how to improve this processing. The utility of these in situ measurements, even without accompanying hyperspectral satellite data, is demonstrated for phytoplankton monitoring. The future evolution of the WATERHYPERNET network is outlined, including geographical expansion, improvements to hardware reliability and to the measurement method (including uncertainty estimation) and plans for daily distribution of near real-time data.
New and Interesting Pine-Associated Hyphomycetes from China
Authors: Tian Wen-Hui , Jin Yan , Liao Yue-Chi , Faraj Turki Kh. , Guo Xin-Yong , Maharachchikumbura Sajeewa S. N. 
Published: August 2024

Pine trees play a crucial role in the forests of Sichuan Province, boasting rich species diversity and a lengthy evolutionary history. However, research and investigation on fungi associated with pine trees are insufficient. This study investigated the diversity of hyphomycetes fungi associated with pine trees in Sichuan Province, China. During the survey, we collected five specimens of hyphomycetes from branches and bark of species of Pinus. Five barcodes were selected for study and sequenced, including ITS, SSU, LSU, TEF1, and RPB2. Morphological examination and multi-locus phylogenetic analyses revealed three new species, viz. Catenulostroma pini sp. nov. within Teratosphaeriaceae, Kirschsteiniothelia longisporum sp. nov. within Kirschsteiniotheliaceae, Sporidesmiella sichuanensis sp. nov. within Junewangiaceae, and two known species, Paradictyoarthrinium diffractum and P. hydei within Paradictyoarthriniaceae, which are the new host records from Pinus species. Catenulostroma pini, distinguished from other species in the genus by its unique morphology, has three conidial morphologies: small terminal helicoconidia, scolecoconidia with many septa, and phragmoconidia conidia. Kirschsteiniothelia longisporum has longer spores when compared to the other species in the genus. According to phylogenetic analysis, Sporidesmiella sichuanensis formed an independent clade sister to S. aquatica and S. juncicola, distinguished by differences in conidial size.
Reflexiones acerca de la actualidad y el futuro del derecho a la vivienda en la Argentina
Authors: Dos Santos Freire Ramiro 
Published: August 2024

Este artículo examina las perspectivas actuales del derecho a la vivienda en Argentina, a partir del análisis de las políticas públicas relacionadas con la integración de villas y barrios populares, sus aspectos políticos, históricos y sociales, y sus bases jurídicas.
Se analizan determinadas políticas públicas de urbanización, centrándose en el ámbito nacional, la Ciudad de Buenos Aires y la provincia de Buenos Aires. Se argumenta que, ante el avance de los programas de ajuste fiscal y la reducción del Estado, es fundamental reivindicar su rol articulador en la implementación de políticas públicas enfocadas en mejorar la vida de la población, desde una perspectiva de derechos. Para ello, es necesario preservar las experiencias y aprendizajes acumulados, como base para la reflexión y el debate sobre el presente. Este artículo busca contribuir a esta reflexión.
Species composition of phytophages on ornamental plants
Authors: Borzykh O. , Vlasova O. , Zatserkliana M. , Vlasova M. 
Published: August 2024

Goal. Monitoring the phytosanitary status and determining the species composition of phytophages on decorative coniferous and deciduous plants.
Methods. Field — determination of the species composition of pests and the dynamics of the number of main species; laboratory — determination of pests selected on experimental plots. Research was conducted in accordance with generally accepted methods in entomology and plant protection.
Results. In the industrial plant nursery of open soil «Megaplant» located in the Kyiv region, Fastiv district, village The monitoring of the phytosanitary state of ornamental plant plantations was carried out in Trilys. The natural saturation of harmful organisms and the level of their harmfulness were studied.
Conclusions. It has been established that plants in industrial nurseries in open ground are damaged by a large number of insects and mites. The most dangerous and widespread on conifer ornamental plants were 8 pests from the following families coccids (Coccidae), bark beetles (Scolytidae), adelgids (Adelgidae), snout beetles (Curculionidae) and spider mites (Tetranychidae); 9 most harmful species from the following families were noted on decorative leafy plants: crambid Snout Moths (Crambidae), mealybugs (Pseudococcidae) and аrmored scales or diaspidids (Diaspididae), eriophyidae mites (Eriophyidae), aphids (Aphididae), snout beetles (Curculionidae), scarab beetles (Scarabaeidae).
ON THE STATE OF DETENTION PLACES IN THE BELARUSIAN LANDS IN THE FIRST HALF OF THE XIX CENTURY AND THE ORGANIZATION OF THE CONVICTS` RE-SOCIALIZATION IN THEM
Authors: Бурый В.Е. 
Published: August 2024

В статье автором рассматривается развитие института отбывания наказания в виде лишения свободы на территории белорусских земель в первой половине XIX в. Изучение архивных дореволюционных материалов позволяет отметить неудовлетворительное состояние белорусских мест лишения свободы в период польско-литовского влияния: ветхость пенитенциарных учреждений к концу XVIII в., требующих значительных денежных средств на ремонт, бессистемная организация в них надзора за осужденными лицами, а также неупорядоченные условия отбывания наказания, в том числе по причине социальной непрестижности работы и низкой оплаты труда администрации тюрем (острогов, крепостей). Акцентируется внимание на том, что после трех разделов Речи Посполитой в конце XVIII в. и присоединения всех земель территории современной Республики Беларусь к Российской империи белорусские места лишения свободы в частности и пенитенциарная система в целом начали медленно, постепенно и целенаправленно реорганизовываться как в организационно-правовом, так и в иных направлениях, в том числе в вопросе ресоциализации осужденных. Вместе с тем, несмотря на принимаемые меры, ситуация в тюрьмах (острогах) в исследуемый период оставалась сложной, поскольку законодателям и правоприменителям приходилось одновременно решать значительное количество давно назревших в этой сфере задач и проблем.
In the article, the author examines the development of the institution of serving a sentence of imprisonment on the territory of the Belarusian lands in the first half of the XIX century. By studying archival pre-revolutionary materials, it is noted that the state of Belarusian places of detention during the period of Polish-Lithuanian influence left much to be desired, since not only these penitentiary institutions by the end of the XVIII century often had a dilapidated condition (requiring significant funds for repairs), but also the organization of supervision of convicted persons in them, as well as the order and conditions of their punishment were haphazard and disordered, including due to the social lack of prestige of work and low wages for the administration of prisons (prisons, fortresses). Attention is focused on the fact that after the three sections of the Polish-Lithuanian Commonwealth at the end of the XVIII century and the annexation of all lands of the territory of the modern Republic of Belarus to the Russian Empire, Belarusian places of detention (in particular) and the penitentiary system (as a whole) slowly and gradually began to be purposefully reorganized both in organizational and legal, and in other directions, including in the issue of the re-socialization of convicts. At the same time, despite all the measures taken, the situation in prisons during the study period remained difficult, since legislators and law enforcement officers had to simultaneously solve a significant number of long-overdue tasks and problems in this area.
THE SPESIFIC ОF INTERNАL АFFАIRS BОDIЕS INTERACTIОN WIТH ОTHЕR LАW ENFОRCЕMЕNT АGENCIЕS IN CОUNTЕRING EMBЕZZLEMЕNT ОF BUDGЕT FUNDS
Authors: Мангасаров Р.А. 
Published: August 2024

Высокий уровень хищений бюджетных средств в России на протяжении последних лет обуславливает поиск эффективных методов противодействия рассматриваемым видам преступлений. В статье рассматриваются актуальные проблемы взаимодействия правоохранительных органов, возникающие в ходе противодействия указанным преступлениям, и предлагаются пути их преодоления. Развитие взаимодействия правоохранительных органов является важным условием эффективного противодействия хищениям бюджетных средств. По мнению автора, последовательная работа по фактам хищений бюджетных средств следственных органов и оперативных подразделений, направленная на внедрение в их деятельность совместных планов, а также специализированных следственно-оперативных групп положительно повлияет на качество раскрытия и расследования рассматриваемых преступлений. Вместе с тем распространение практики совместного проведения проверочных мероприятий правоохранительными органами и контрольно-надзорными структурами в рамках межведомственных планов, по мнению автора, повысит результаты их работы и уровень межведомственного взаимодействия в борьбе с хищениями бюджетных средств. На основе отечественного опыта автором выделены некоторые направления совершенствования противодействия хищениям бюджетных средств, связанные с ведомственным и межведомственным взаимодействием, а также предлагаются мероприятия по повышению результативности ОРД правоохранительных органов в рамках противодействия рассматриваемым преступлениям.
The high level of embezzlement of budget funds in Russia over the past few years has led to the search for effective methods of countering these types of crimes. The article examines the actual problems of interaction between law enforcement agencies that arise in the course of countering these crimes, аnd suggеsts wаys tо оvercоmе thеm. The dеvеlоpment оf cooperation between law enforcement agencies is an important condition for effective counteraction to embezzlement of budget funds. According to the author, the consistent work of investigative bodies and operational units aimed at introducing joint plans into their activities, on the facts of embezzlement of budget funds, and specialized investigative and operational groups, will positively affect the quality of disclosure and investigation of the crimes under consideration. At the same time, the spread of the practice of joint verification activities by law enforcement agencies and control and supervisory structures within the framework of interdepartmental plans, according to the author, will increase the results of their work and the level of interdepartmental interaction in the fight against embezzlement of budget funds. Based on domestic experience, the author identifies some areas of improvement in countering embezzlement of budget funds related to departmental and interdepartmental interaction, and suggests measures to improve thе еffеctiveness оf оpеrаtiоnаl invеstigаtivе аctivitiеs оf intеrnаl аffаirs bоdiеs tо counteract the crimes in question.