bluuebunny/crossref_metadata_2025_split huggingface dataset:
La capacité négative en thérapie : « Laisser le Vide pour faire advenir le Plein »
Authors: Ambroise Pascale 
Published: July 2024

Cet article explore l’importance de la « capacité négative » en psychothérapie, un concept introduit par Bion en 1965, qui implique d’accepter l’inconnu sans agir immédiatement. Cette approche est particulièrement pertinente dans le traitement des enfants, notamment ceux atteints de troubles du spectre autistique. L’auteure illustre son propos avec des cas d’enfants où le thérapeute doit tolérer le silence, l’inaction et l’incompréhension, permettant ainsi l’émergence de la relation et la transformation de l’enfant. Elle souligne la nécessité d’un cadre thérapeutique stable pour la construction de l’identité de l’enfant et son développement psychique. La thérapie est comparée à une vallée dans la peinture chinoise, un espace vide qui nourrit et permet la croissance.
The Medical Consequences of Child Abuse and Neglect
Authors: Palaszynski Karen M. , Nemeroff Charles B. 
Published: July 2024

CME Educational Objectives

1.
Review the basic components of the acute stress response, including the hypothalamic-pituitaryadrenal axis (HPA), corticotropinreleasing factor system, and locus coeruleus-norepinephrine system.

2.
Explain the potential, long-term medical consequences of child abuse, including risk for heart disease and obesity, as well as alterations in HPA axis reactivity, the autonomic nervous system, and immune function in adults who were exposed to early-life trauma.

3.
List other long-standing consequences associated with abuse.
Les cinéphonies, des « chefs-d’œuvre expliqués par l’image » ?
Authors: Taillandier-Guittard Inès 
Published: July 2024

Au milieu des années 1930, Émile Vuillermoz supervise la réalisation d’une série de sept courts métrages produits par la Compagnie des Grands Artistes Internationaux (CGAI), qu’il intitule « cinéphonies », considérées dans la littérature existante comme les ancêtres du vidéoclip. Ce terme désigne un objet audiovisuel dont la visée est double. Il s’agit d’une part de filmer les interprètes (cette captation est dénommée « film technique »), d’autre part de proposer de l’œuvre exécutée une transposition cinématographique (la cinéphonie proprement dite). Cet article se propose d’examiner le statut de ces courts-métrages, partagés entre ambition didactique et visée promotionnelle. Il tente en outre d’envisager le médium visuel non pas comme un pur miroir du son (si complexe que soit cette relation spéculaire), mais comme le fruit de métamorphoses successives qui construisent, à l’intérieur du plan et entre les plans, une logique propre. Trois cinéphonies seront plus particulièrement analysées : La Fontaine d’Aréthuse et Jeune fille au jardin de Dimitri Kirsanoff, ainsi que La Valse brillante de Chopin de Max Ophuls.
De l’instrument joué à la pratique représentée : comprendre les figures de flûtistes dans l’iconographie recuay (sierra nord-centrale du Pérou, 100‑800 n.è.)
Authors: Ferras Mélanie , Moretti Alexia 
Published: July 2024

L’analyse des pratiques musicales et sonores propres à la culture recuay (100‑700 n.è.), dans la sierra nord-centrale de l’actuel Pérou, se heurte à plusieurs inconnues documentaires. Il existe en effet une répartition déséquilibrée des données exploitables : aux contextes archéologiques et aux instruments, peu connus et peu documentés, s’oppose une riche imagerie présente sur des céramiques cérémonielles où sont représentées des scènes, détaillées et récurrentes, dans lesquelles interviennent des instruments de musique.Les céramiques qui représentent des flûtistes sont particulièrement intéressantes. La figure de l’instrumentiste y est toujours centrale et ses attributs le rattachent au domaine sacerdotal. Il serait toutefois réducteur de s’arrêter à l’affirmation selon laquelle l’emploi du son de la flûte est en lien avec une cérémonie. Les analyses formelles et symboliques des motifs représentés permettent d’identifier, sur une même pièce, la juxtaposition de niveaux de réalités distincts qui entrent en contact grâce à la présence de la flûte.Dans le cas présenté, l’approche iconographique offre la possibilité de faire revivre scientifiquement des objets décontextualisés. Ce faisant, elle met en évidence des informations qui, véhiculées par les images, témoignent de la conception du monde d’une culture.
L’archéologie verticale ou l’étude des graffiti anciens : du document iconographique à la source historique (xie‑xvie siècles)
Authors: Gaubert Aymeric 
Published: July 2024

Le Moyen Âge et la Renaissance ont produit un ensemble de signes, d’inscriptions et de graffiti qui fait sens dans une société de l’image. Un tel langage iconographique a donné lieu à des usages multiples du mur, révélant une pratique graffitologique qui semble normale, diversifiée, souvent dévotionnelle, mais largement méconnue. Cette tradition graphique, quasiment absente des sources écrites habituelles, reste à documenter en s’appuyant notamment sur le corpus conservé à la forteresse de Loches en Indre-et-Loire. En dépit des difficultés d’identification, d’attribution et de datation, il s’agit de montrer que le graffiti fournit une authentique voie/x aux sociétés anciennes, renvoyant à des perceptions, des croyances et des pratiques passées à éclaircir et à contextualiser au sein d’une véritable archéologie de la trace. À la fois patrimoine matériel (production graphique), patrimoine culturel (témoignage historique) et patrimoine immatériel (geste), le graffiti constitue une archive lapidaire digne d’intérêt faisant désormais l’objet d’une nouvelle science en construction : la graffitologie.
Exploring the Clinical Characteristics of Patients with Implanted Cardioverter Defibrillator Shocks after Coronavirus Disease 2019 Infection: A Comprehensive Analysis
Authors: Sun Jianying , Ma Juan , Wei Feiyu , Ma Yazhe , Zhang Xi , Gao Xiaolong , Ma Tao , Guo Jia , Li Xiuhua , Fan Jie 
Published: July 2024

AbstractBackground:The relationship between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and implantable cardioverter defibrillator (ICD) shock remains unclear. We analyzed the characteristics of patients receiving shocks after SARS-CoV-2 infection to explore the causes of these shocks and to provide information for subsequent treatment.Subjects and Methods:We retrospectively analyzed the data from seven patients hospitalized at First People’s Hospital of Yunnan Province between December 2022 and January 2023 after experiencing ICD shocks or ventricular arrhythmias following SARS-CoV-2 infection. We collected baseline information, data related to device parameters and events, and laboratory results to analyze the causes of electrical shocks.Results:All patients received ICD implantation at our hospital. The mean age of the patients was 67 ± 10 years. Four patients underwent implantation for primary prevention and three for secondary prevention. These patients received 80 ICD shocks after SARS-CoV-2 infection, 71 (89%), and 9 (11%) of which were the treatment for ventricular tachycardia and atrial fibrillation, respectively. There were 54 antitachycardia pacing treatments, of which 48 arrhythmic events were terminated through antitachycardia pacing, and 6 were not. Laboratory data revealed six patients had blood potassium levels below 4.0 mM. Five patients had blood calcium levels below 2.11 mmol/L. Four patients had elevated troponin concentrations (0.030–0.297 ng/mL). All patients had significantly elevated N-terminal pro-B-type natriuretic peptide levels (608.8–25,758 pg/mL). Six patients had a QT interval of >440 ms and a mean QT interval of 460 ± 46 ms.Conclusion:SARS-CoV-2 infection may be associated with ICD shocks. Clinicians should pay close attention to patients with ICDs after SARS-CoV-2 infection and actively eliminate arrhythmogenic triggers to minimize the likelihood of ICD shock.
Ayurvedic Management of Guttate Psoriasis (Kitibha Kushtha) in Children: A Case Report
Authors: Chaudhary Naresh B. , Patir Nikita , Kori Virendra K. , Bhinde Sagar M. , Rani Renu 
Published: July 2024

Abstract
Every day, the number of people with autoimmune diseases increases. It is still unclear what specifically causes autoimmune diseases. One such condition is guttate psoriasis. It has a correlation with Kitibha Kushtha in Ayurveda. It occurs most often in children and young adults. Panchakarma is a well-known measure to improve the quality of life and prevention of recurrence in chronic diseases. As per the case study, an adolescent girl aged 13 years complained asymmetrical grouped skin lesions with a blackish-brown area covered by lesions on the dorsal and ventral aspects of B/L hands, more on the feet and in groin region and some on the back and all over the body for 10 months. Skin lesions were not associated with any discharge or itching. The patient was treated with Ayurveda interventions. Two sittings of Virechana along with Ayurvedic oral and local medicines and wholesome dietary regimen were given for 4 months. Encouraging relief from the above symptoms was observed after treatment. The patient has shown well tolerance and satisfactory adherence to the given treatment. No adverse event was reported during the course of therapy.
Opinion of medical students and instructors on the challenges of in-person learning postcoronavirus disease 2019 pandemic
Authors: Alsunni Ahmed A. , Latif Rabia , Aldossary Deena A. , Aloraifi Lama I. 
Published: July 2024

Abstract:

BACKGROUND:
Several universities switched back to face-to-face teaching in 2022 after 2 years of online classes during the coronavirus disease 2019 (COVID-19) crisis. There is no data from these students/teachers on the challenges in postpandemic face-to-face teaching and learning. The current study’s aim was to identify the challenges of face-to-face teaching and learning postpandemic from the perspective of students and instructors.

MATERIALS AND METHODS:
Undergraduate medical students (n = 210) registered in Imam Abdulrahman Bin Faisal University and instructors (n = 72) filled out online questionnaires from November 2022 to March 2023 on teaching–learning challenges in the postpandemic period. The questionnaires asked students about their interest in education, scores, degree of shyness, how clear the voices of the instructors wearing face masks were, fear of COVID-19, preferred mode of teaching, and advantages/disadvantages of face-to-face teaching. Descriptive statistics included frequencies and percentages for qualitative variables; Chi-square test was applied to assess association between categorical variables.

RESULTS:
Students reported a decrease in their educational interest postpandemic (47.1%), diffidence in interaction (42.4%), blurred teachers’ voices because of the face masks (63.3%), and lack of teachers’ empathy (47.6%). There was a significant association between preclinical year students and a decrease in educational interest (P = 0.002), diffidence in class interactions (P = 0.001), and fear of contracting COVID-19 infection while interacting with teachers (P = 0.04). Instructors complained of a decrease in students’ interest in education (65.3%), especially the instructors of the clinical years (16.7% vs. 2.1%; P = 0.022). About 10% students reported taking leave from university on purpose due to fear of contracting COVID-19 infection; students and instructors both supported lecture recordings (98.6% and 63.9%, respectively). The students’ and instructors’ preferred platform for learning was “hybrid” (80.5% and 63.9%, respectively).

CONCLUSION:
Challenges faced by the students include decreased interest in learning, drop in scores, muffled voices because of the face masks, increased shyness, waste of time in commutes, lack of flexibility in schedules, increased workload, and fear of catching COVID-19 infection. There is strong support for hybrid/blended learning and recording lectures.
The diagnostic accuracy of the Arabic version of the Pediatric Sleep Questionnaire for screening for pediatric sleep-related breathing disorders in Saudi children
Authors: Alkhateeb Ahmed A. , Alrusayyis Danah F. , Alrashedi Essa A. , Alkhunaizi Lama T. , Alali Shahad M. , Alghamdi Amal A. 
Published: July 2024

Abstract:

BACKGROUND:
Pediatric Sleep Questionnaire (PSQ) is a valid, reliable tool for screening for sleep-related breathing disorders (SRBDs) translated into several languages since 2000. The diagnostic accuracy of an Arabic version of the PSQ has never been tested. Our aim was to translate the original version of PSQ into Arabic (Arabic-PSQ), validate it as a reliable screening tool, and compare it to the gold standard diagnostic method for SRBDs.

MATERIALS AND METHODS:
This was a prospective longitudinal study of 54 children (2–14 years) who were to undergo polysomnography (PSG). SRBD was assessed by administering the Arabic version of PSQ to the parents of these children. The validity and reliability of the Arabic-PSQ were assessed. Data were analyzed using Stata 16. Correlation between with polysomnographic indices and PSQ scores, as well as measurement of the diagnostic accuracy were determined. Receiver operating characteristic analysis between the mean PSQ scores and binary PSG results was done and the area under curve (AUC) value was calculated.

RESULTS:
Thirty-four (63%) children were diagnosed with obstructive sleep apnea by PSG (Apnea–Hypopnea Index [AHI] ≥1), 26 of whom were accurately identified with the Arabic-PSQ (76.5%). Arabic-PSQ showed comparable validity and reliability. Using a cutoff of 0.33, the score showed a significant correlation with AHI: Rs: 0.30 (P = 0.029). The sensitivity was 76.5%, the specificity was 50%, the positive predictive was 72.2%, the negative predictive value was 55.6%, the positive likelihood ratio was 1.63, and the negative likelihood ratio was 0.37.

CONCLUSIONS:
The Arabic-PSQ is a valid tool for the screening of Arabic-speaking populations for SRBD. It is valuable for directing the diagnostic approach in a timely and cost-effective manner.
Impulsiveness, suicide, and aggression in a sample of patients with disorders of methyl amphetamine use
Authors: Ali Moatazbellah I. , Rashad Mahmoud M. , Alzain Nasser M. , Al-Awad Feras A. , Alzaharani Mohammed A. , Alshamarani Abdulsalam S. , Almuqahwi Mohammed S. , Afifi Shrief Y. 
Published: July 2024

Abstract:

BACKGROUND:
Research has showed a link between patients with methamphetamine dependence and the risk of impulsiveness, aggression, and the risk of suicide. But, this link has not been studied in patients abusing methamphetamine, and it is unknown how impulsiveness, aggression, and the risk of suicide affect them.

MATERIALS AND METHODS:
This cross-sectional study included 130 adult patients diagnosed with the disorder of the use of amphetamine, methamphetamine, cannabinoids, alcohol, other substances, and polysubstance admitted in the Addiction Department for Mental Health. Participants were interviewed for detailed psychiatric history using a structured questionnaire comprising of structured clinical interview for diagnosis I, Arabic version of the Barratt Impulsiveness Scale-11 (BIS), Beck Scale for Suicidal Ideation for the evaluation of suicidal ideation and behavior, and the Aggression and Hostility scale for adolescents and youth. SPSS was used for data analysis; Initial analysis included descriptive statistics: frequencies and percentages for categorical variables and mean and standard deviation for continuous variables. Chi-square test/Fisher’s exact test assessed for association between categorical variables, whereas one-way analysis of variance (ANOVA)/ Kruskal–Wallis test was used to compare continuous variables.

RESULTS:
Patients who used methamphetamine either alone (23%) or with polysubstance (42.6%) were associated with higher suicidal risk than patients who did use other substances than methamphetamine (36.1%). A comparison of the three groups on impulsivity, showed significant difference regarding total scores, motor preservation, and non-planning self-control. No significant differences found between three groups on the aggression scores.

CONCLUSIONS:
There was a higher rate of impulsivity and suicidal risk in patients with methamphetamine dependence in comparison to dependence on other substances, while there was no difference with regard to aggression between patients with methamphetamine dependence and those dependent on other substances. This finding raises the issue of methamphetamine use disorder as a new substance of dependence.
Analysis of Diffuse Large B Cell Lymphoma using Immunohistochemistry to Identify Double Expressor Diffuse Large B Cell Lymphoma among Germinal Centre and Non Germinal Centre B Cell Subtypes
Authors: Rani E R Jyothi , Scaria Jasmin , Sathi P P 
Published: July 2024

ABSTRACT

Background:
Diffuse large B cell lymphoma (DLBCL) within non-Hodgkin lymphoma has several morphologic and clinicopathologic variants. DLBCL has two prognostically important subtypes, germinal center B cell (GCB) and nongerminal center (Non-GCB) with the non-GCB having an inferior outcome. Immunohistochemical co-expression of cellular myelocytomatosis (CMYC) and BCL2 in DLBCL has poor prognosis and is considered as double-expressor lymphoma (DEL).

Aims and Objectives:
This study was done to identify DEL using immunohistochemistry among GCB and non-GCB DLBCL and to assess their treatment response.

Methods and Material:
A retrospective analysis of 97 DLBCL cases received in our department was done. Formalin-fixed paraffin blocks were used to prepare Hematoxylin and eosin–stained sections, immunohistochemical subtyping (into GCB and non-GCB using CD10, BCL6, and MUM1) and further to identify DEL (using CMYC and BCL2).

Statistical Analysis:
Analysis was done using Chi-square test (Statistical Package for Social Sciences version 18), and P <.05 was considered significant. Kaplan-Meier test was used to estimate overall survival.

Results:
Of the total 97 DLBCL cases analyzed, 33 (34%) were DEL and 64 (66%) were non-DEL. Of the DEL, 13 (13.40%) were GCB subtype and 20 (20.6%) were non-GCB. However, there was no statistically significant difference in the overall survival and treatment response between DEL and non-DEL.

Conclusions:
In this study, we found that DEL constituted about one-third of the total DLBCL and within the DEL non-GCB subtype was more common. Further studies should be performed in large population to study the difference in clinical outcome.
IgG4-related Renal Disease Case Report and Review of Literature
Authors: Sen Arijit , Kotian Vineet Gopal , Kashif Ahmed Waheed , Datt Bhaskar 
Published: July 2024

ABSTRACT

IgG4-related disease (IgG4-RD) is a clinical entity that involves multiple organs and is characterized by high levels of serum IgG4. We present a case of an elderly male reporting fatigue and weight loss, who after extensive workup, was diagnosed as a case of IgG4-related renal disease on kidney biopsy.

Clinical Profile:
A 73-year-old male patient, a reformed smoker with a history of acute coronary syndrome and bronchial asthma, presented with fatigue and weight loss for 6 months. Clinical examination was unremarkable. Investigations revealed mild anemia, azotemia, hyperglobulinemia, bland urinary sediment, insignificant proteinuria, and symmetrically enlarged kidneys. A kidney biopsy was performed, which demonstrated features of IgG4-related tubulointerstitial nephritis (TIN). Simultaneous serological investigations revealed a Kappa/Lambda ratio of 2.12, IgG–3110 mg/dL, and IgG4–3.56 g/L. The patient was treated with oral prednisolone for 6 months.

Discussion:
IgG4-related disease is a multisystem immune fibro-inflammatory disorder of the elderly with a male preponderance, which involves all organs except the synovium. IgG4-related TIN presents with an insidious rise of creatinine, elevated IgG4 levels, peripheral eosinophilia in 40% of individuals, anti-nuclear antibodies (ANA) positive status in many, and hypocomplementemia. It is characterized by lymphoplasmacytic infiltration with IgG4+ plasma cells with IgG4/IgG ratio >40%, eosinophilic infiltrate, storiform fibrosis, and immune complexes in the tubular basement membrane. The mainstay of treatment is oral corticosteroids, with relapse noted in the majority, followed by a chronic indolent course.

Conclusion:
IgG4-related diseases are an emerging entity and have only been recently recognized. Awareness of the disease and a high index of suspicion is essential for early diagnosis to avoid irreversible organ damage.
Burden of Care, Quality of Life, and Coping Strategies among Spouses of Alcohol-Dependence Patients in Tertiary Health Care Centre
Authors: Singh Pratishtha , Javadekar Archana , Chaudhury Suprakash , Saldanha Daniel 
Published: July 2024

ABSTRACT

Background:
Caregiving to a patient with substance-abuse is quite stressful and places an additional burden to the caregiver which in turn have a huge impact on their quality of life. To overcome this burden and improve their quality of life, caregivers adopt some coping strategies.

Aim:
To study the burden of care, coping strategies and quality of life among spouses of alcohol-dependence patients.

Methodology:
In this case control study, 100 spouses of diagnosed alcohol-dependence patients were taken as cases and the same number of age and sex-matched spouses of normal healthy individuals were taken as controls. AUDIT – C scale was applied to diagnose alcohol dependence in patients. M.I.N.I scale used on spouses, to rule out any chronic psychiatric illness. Burden Interview Schedule (BIS), EUROHIS-QOL scale, and Brief COPE Scale were used to find the burden on spouses, their quality of life, and coping strategies used by them.

Results:
In this study, the mean burden of care score (BIS) was significantly higher in cases (35.11 ± 4.97) as compared to that in controls (16.56 ± 9.98). Mean scores for BIS subdomains were also significantly higher in cases as compared to that in controls. There was no significant difference in the EUROHIS-QOL ratings between the cases and controls. Mean BRIEF COPE scale scores were significantly lower in cases (77.39 ± 18.10) as compared to that in controls (82.89 ± 16.43). The only difference between the two groups that was statistically significant was the avoidant coping score.

Conclusion:
The findings of this study showed that spouses of alcohol-dependent patients experience a high burden of care in all subdomains. Adaptive coping strategies were mainly taken by spouses of alcohol dependence patients, to cope with the situation. The quality of life of spouses of alcohol-dependent patients was not affected.