bluuebunny/crossref_metadata_2025_split huggingface dataset:
Computing the various pathways of penicillin synthesis and their molar yields
Authors: Prauße Maria T. E. , Schäuble Sascha , Guthke Reinhard , Schuster Stefan 
Published: July 2015

ABSTRACTMore than 80 years after its discovery, penicillin is still a widely used and commercially highly important antibiotic. Here, we analyse the metabolic network of penicillin synthesis in Penicillium chrysogenum based on the concept of elementary flux modes. In particular, we consider the synthesis of the invariant molecular core of the various subtypes of penicillin and the two major ways of incorporating sulfur: transsulfuration and direct sulfhydrylation. 66 elementary modes producing this invariant core are obtained. These show four different yields with respect to glucose, notably ½, 2/5, 1/3, and 2/7, with the highest yield of ½ occurring only when direct sulfhydrylation is used and α‐aminoadipate is completely recycled. In the case of no recycling of this intermediate, we find the maximum yield to be 2/7. We compare these values with earlier literature values. Our analysis provides a systematic overview of the redundancy in penicillin synthesis and a detailed insight into the corresponding routes. Moreover, we derive suggestions for potential knockouts that could increase the average yield. Biotechnol. Bioeng. 2016;113: 173–181. © 2015 Wiley Periodicals, Inc.
Intrinsic Kinetics of Esterification of Fatty Acids Catalyzed by Supported Ionic Liquid Catalysts
Authors: Heer Parminder Kaur Khabinder Singh , Chabukswar Deepak D. , Gaikar Vilas G. 
Published: July 2015

AbstractEsterification of palm fatty acid distillate with methanol was investigated for intrinsic kinetics and regarding the effect of catalyst loading, temperature, and methanol to feed molar ratio using ionic liquid acidic catalysts covalently attached to a polystyrene support. The kinetic parameters of the Langmuir‐Hinshelwood‐Hougan‐Watson model of the reaction are determined for comparison with those using p‐toluenesulfonic acid and methanesulfonic acid as homogeneous catalysts considering the phase split of the reaction mixture into two liquid phases during the reaction. The intrinsic parameters could predict the dynamic behavior of the system under various operating conditions.
ChemInform Abstract: Revisit of Pressure‐Induced Phase Transition in PbSe: Crystal Structure, and Thermoelastic and Electrical Properties.
Authors: Wang Shanmin , et al.  
Published: July 2015

AbstractThe pressure‐induced phase transition in PbSe is characterized by in situ high‐pressure/high‐temperature synchrotron XRD, electrical resistivity measurements, and DFT band structure calculations.
ChemInform Abstract: Structure and Magnetism of Sr3NiSb2O9.
Authors: Battle Peter D. , Chin Chun‐Mann , Evers Sophie I. , Westwood Mark 
Published: July 2015

AbstractThe title compound is prepared from a stoichiometric mixture of SrCO3, Sb2O5, and NiO (alumina crucible, 1250 °C, 8 d) and characterized by X‐ray and neutron powder diffraction, and magnetic measurements.
ChemInform Abstract: Hydrogen Diffusion in MgH2 Doped with Ti, Mn and Fe.
Authors: Koteski Vasil , Belosevic‐Cavor Jelena , Batalovic Katarina , Radakovic Jana , Umicevic Ana 
Published: July 2015

AbstractThe role of Ti, Fe, and Mn on H diffusion in MgH2 is studied by DFT calculations using the PW91 generalized gradient functional on a 71 atom 2 x 2 x 3 supercell of rutile‐type MgH2 in which one Mg host atom is replaced by the dopant.
ChemInform Abstract: Syntheses, Crystal Structures, and NLO Properties of the Quaternary Sulfides RE3Sb0.33SiS7 (RE: La, Pr).
Authors: Zhao Hua‐Jun 
Published: July 2015

AbstractThe title compounds are synthesized by solid state reactions of stoichiometric mixtures of the elements (evacuated silica tubes, 1223 K, 4 d).
ChemInform Abstract: Li4Ti5O12 Hollow Mesoporous Microspheres Assembled from Nanoparticles for High Rate Lithium‐Ion Battery Anodes.
Authors: Cao Liyun , Hui Yani , Ouyang Haibo , Huang Jianfeng , Xu Zhanwei , Li Jiayin , Zhang Wanzhuo , Chai Simin , Guo Shouwu 
Published: July 2015

AbstractLi4Ti5O12 hollow mesoporous microspheres assembled from nanoparticles are prepared by hydrothermal reaction of LiOH and TiO2 (autoclave, 160 °C, 2 d) and subsequent calcination (400 °C, 2 h).
ChemInform Abstract: Synthesis and Crystal Structure of a Novel Layered Barium Antimonate Ba2Sb7O13(OH) with Mixed‐Valence Antimony.
Authors: Geng Lei , Meng Chang‐Yu , Wang Miao‐Miao , Dai Kai , Lin Chen‐Sheng , Cheng Wen‐Dan 
Published: July 2015

AbstractPale brown crystals of Ba2Sb7O13(OH) are prepared by hydrothermal reaction of Ba(OH)2, Sb2O3, KCl, and H2O (autoclave, 190 °C, 4 d).
ChemInform Abstract: A New Synthetic Route to Rhenium and Iodine Oxide Fluoride Anions: The Reaction Between Oxoanions and Sulfur Tetrafluoride.
Authors: Goettel James T. , Turnbull Douglas , Gerken Michael 
Published: July 2015

AbstractOne‐step preparation of [Ag(MeCN)x][ReVIIO2F4] (x = 0, 2, 4) is achieved by addition of excess SF4 to a frozen MeCN solution of Ag[ReO4] at ‐196 °C followed by warming up to room temp.
ChemInform Abstract: Palladium‐Catalyzed Enantioselective Allylic Substitution in the Presence of Monodentate Furanoside Phosphoramidites.
Authors: Majdecki Maciej , Jurczak Janusz , Bauer Tomasz 
Published: July 2015

AbstractA library of monodentate furanoside phosphoramidites is prepared and applied in the Pd‐catalyzed allylic alkylation and amination.
ChemInform Abstract: Copper‐Catalyzed Base‐Accelerated Direct Oxidation of C—H Bond to Synthesize Benzils, Isatins, and Quinoxalines with Molecular Oxygen as Terminal Oxidant.
Authors: Yu Jing‐Wen , Mao Shuai , Wang Yong‐Qiang 
Published: July 2015

AbstractA mild, general, and efficient copper (II)‐catalyzed base‐accelerated oxidation of the C—H bond to synthesize benzils and isatins is developed.
ChemInform Abstract: Organic Hypervalent Iodine(III) Catalyzed ipso‐Hydroxylation of Aryl‐ and Alkylboronic Acids/Esters.
Authors: Chatterjee Nachiketa , Goswami Avijit 
Published: July 2015

AbstractA novel methodology for the iodine‐catalyzed ipso‐hydroxylation of aryl and alkylboronic acids and esters is developed affording diversely functionalized aromatic and aliphatic alcohols.
ChemInform Abstract: A Simple Iridicycle Catalyst for Efficient Transfer Hydrogenation of N‐Heterocycles in Water.
Authors: Talwar Dinesh , Li Ho Yin , Durham Emma , Xiao Jianliang 
Published: July 2015

AbstractFirst time, a cyclometalated iridium complex is used to catalyze the transfer hydrogenation of (iso)quinolines, indoles, and pyridinium salts in an aqueous solution of HCOOH/HCOONa under mild conditions.
ChemInform Abstract: Synthesis of 2‐Nitroso Heterocyclic Ketene Aminals with (E)‐1‐Nitro‐4‐(2‐nitrovinyl)‐benzene as the Nitrosating Agent.
Authors: Yu Fu‐Chao , Hao Xiao‐Pan , Huang Rong , Yan Sheng‐Jiao , Lin Jun 
Published: July 2015

AbstractThe reaction proceeds with 2‐aryloylmethylidene‐1,3‐diazacycloalkanes with high regioselectivity forming the corresponding α‐nitroso compounds.
ChemInform Abstract: Transition‐Metal‐Free Decarboxylation of Dimethyl Malonate: An Efficient Construction of α‐Amino Acid Esters Using TBAI/TBHP.
Authors: Zhang Jie , Shao Ying , Wang Yaxiong , Li Huihuang , Xu Dongmei , Wan Xiaobing 
Published: July 2015

AbstractThe tandem hydrolysis‐decarboxylation‐nucleophilic substitution of dimethyl malonate with primary, secondary, and tertiary aromatic amines under mild conditions gives α‐amino esters in moderate to good yields.
ChemInform Abstract: Catalytic C—H Imidation of Aromatic Cores of Functional Molecules: Ligand‐Accelerated Cu Catalysis and Application to Materials‐ and Biology‐Oriented Aromatics.
Authors: Kawakami Takahiro , Murakami Kei , Itami Kenichiro 
Published: July 2015

AbstractThe direct C—H imidation of a variety of arenes and heteroarenes is possible with N‐fluorobenzenesulfonamide in the presence of CuBr and 6,6′‐dimethyl‐2,2′‐bipyridine.
ChemInform Abstract: SnCl4—Zn: A Novel Reductive System for Deoxygenative Coupling of Aliphatic, Aromatic, Chalcone Epoxide, and Indanone Carbonyl Compounds to Olefins.
Authors: Pathe Gulab Khushalrao , Ahmed Naseem 
Published: July 2015

AbstractA novel, efficient, and economical tin‐reagent for the reductive cross‐coupling reaction of carbonyl compounds under McMurry coupling with aliphatic and aromatic ketones, aldehydes, chalcone epoxides, and indanones is developed.
ChemInform Abstract: Iron‐Catalyzed Trifluoromethylation of Enamide.
Authors: Rey‐Rodriguez Romain , Retailleau Pascal , Bonnet Pascal , Gillaizeau Isabelle 
Published: July 2015

AbstractThe first example of an Fe(II)‐catalyzed trifluoromethylation of enamides, e.g. (I), (IV), (VI), (VIII), and (X), using Togni′s reagent (II) as electrophilic CF3 source is reported.
ChemInform Abstract: C—C Coupling of Ketones with Methanol Catalyzed by a N‐Heterocyclic Carbene—Phosphine Iridium Complex.
Authors: Quan Xu , Kerdphon Sutthichat , Andersson Pher G. 
Published: July 2015

AbstractThe title transformation proceeds via a hydrogen transfer reaction involving the dehydrogenation of MeOH to form formaldehyde, followed by aldol condensation with the ketone (I) and (IV).
ChemInform Abstract: Photocatalyzed Site‐Selective C—H to C—C Conversion of Aliphatic Nitriles.
Authors: Yamada Keiichi , Okada Megumi , Fukuyama Takahide , Ravelli Davide , Fagnoni Maurizio , Ryu Ilhyong 
Published: July 2015

AbstractIn most cases, the alkylation takes place at the γ‐position.
ChemInform Abstract: [Et3NH][HSO4]‐Catalyzed Eco‐Friendly and Expeditious Synthesis of Thiazolidine and Oxazolidine Derivatives.
Authors: Malla Ali Mohammed , Parveen Mehtab , Ahmad Faheem , Azaz Shaista , Alam Mahboob 
Published: July 2015

AbstractThe title compounds are obtained by one‐pot three‐component reaction of cyclic diketones (I), cyanates (II) or (V) or (VII), and ethyl chloroacetate (III) under solvent‐free, mild, and environmentally benign conditions.
ChemInform Abstract: Ambiphilic Properties of SF5CF2CF2Br Derived Perfluorinated Radical in Addition Reactions Across Carbon—Carbon Double Bonds.
Authors: Dudzinski Piotr , Matsnev Andrej V. , Thrasher Joseph S. , Haufe Guenter 
Published: July 2015

AbstractThe ambiphilic character of the F5S—CF2‐CF2· radical is exploited in addition reactions to both electron‐rich and ‐deficient alkenes.
ChemInform Abstract: Oxidation of Secondary Alcohols by Conventional and Microwave—Assisted Methods Using Molybdenum Complexes of ONO Donor Ligands.
Authors: Maurya Mannar R. , Dhaka Sarita , Avecilla Fernando 
Published: July 2015

AbstractNewly synthesized dioxidomolybdenum(VI) complexes are tested for the oxidation of secondary alcohols (I) using conventional liquid phase and microwave‐assisted method with 30% aqueous H2O2 as oxidant giving the respective ketones (II).
ChemInform Abstract: The Synthesis and Ring Opening of 3‐Aroyl(heteroaroyl)‐1,2‐dicyanocyclopropane‐1,2‐dicarboxylates.
Authors: Karpov Sergey V. , Kayukov Yakov S. , Grigor'ev Arthur A. , Tafeenko Victor A. 
Published: July 2015

AbstractNovel electron‐deficient cyclopropanes are prepared from glyoxal hydrates and methyl cyanoacetate.
ChemInform Abstract: Cobalt‐Catalyzed Intermolecular Stereoselective Bisbenzylation of Alkynes.
Authors: Komeyama Kimihiro , Asakura Ryota , Fukuoka Hiroshi , Takaki Ken 
Published: July 2015

AbstractThe cobalt‐catalyzed reaction of benzyl bromides with alkynes in the presence of manganese as reductant produces cis‐1,2‐bisbenzylated alkenes.
ChemInform Abstract: Direct Amide Synthesis from Equimolar Amounts of Carboxylic Acid and Amine Catalyzed by Mesoporous Silica SBA‐15.
Authors: Tamura Mizuki , Murase Daisuke , Komura Kenichi 
Published: July 2015

AbstractThe heterogeneous amidation reaction proves successful for the transformation of aryl and alkyl carboxylic acids as well as N‐Boc‐protected amino acids with primary aliphatic amines and secondary amines such as morpholine while delivering the desired amides in high to excellent yields.
ChemInform Abstract: Concise Synthesis of Semicarbazides and Formylhydrazines via Direct Addition Reaction Between Aromatic Azoarenes and N‐Substituted Formamides.
Authors: Liu Defu , Mao Jincheng , Rong Guangwei , Yan Hong , Zheng Yang , Chen Jie 
Published: July 2015

AbstractThe direct C—H addition of formamides to the N=N double bond of aromatic azo compounds under transition‐metal‐free catalytic conditions is presented.
ChemInform Abstract: A Metalloenzyme‐Like Catalytic System for the Chemoselective Oxidative Cross‐Coupling of Primary Amines to Imines under Ambient Conditions.
Authors: Largeron Martine , Fleury Maurice‐Bernard 
Published: July 2015

AbstractThe direct oxidative cross‐coupling of primary imines is a challenging transformation as homocoupling is usually preferred.
ChemInform Abstract: Metal‐Free Oxidative Functionalization of C(sp3)—H Bond Adjacent to Oxygen and Radical Addition to Olefins.
Authors: Zhou Wei , Qian Ping , Zhao Jincan , Fang Hong , Han Jianlin , Pan Yi 
Published: July 2015

AbstractPrimary and secondary alcohols as well as cyclic ethers add regioselectively to the double bond of N‐allyl and N‐homoallyl amides.
ChemInform Abstract: Sulfonamide Formation from Sodium Sulfinates and Amines or Ammonia under Metal‐Free Conditions at Ambient Temperature.
Authors: Yang Kai , Ke Miaolin , Lin Yuanguang , Song Qiuling 
Published: July 2015

AbstractA metal‐, base‐, ligand‐, and additive‐free protocol for the efficient construction of a variety of sulfonamides is developed.
ChemInform Abstract: Aza‐Wacker‐Type Reaction Between Electron‐Deficient Olefins and N‐Alkylsulfonamides.
Authors: Hu Huayou , Tian Jiaxin , Liu Yun , Liu Yong , Shi Fei , Wang Xiang , Kan Yuhe , Wang Chao 
Published: July 2015

AbstractA scalable protocol for the oxidative amination of electron‐deficient olefins in presence of methanesulfonic acid is presented.
ChemInform Abstract: Manganese Catalyzed Sulfenylation of N‐Methyl Amides with Arenesulfonyl Hydrazides.
Authors: Sun Jinwei , Wang Yi , Pan Yi 
Published: July 2015

AbstractOxidative sulfenylation of N‐methyl amides with arenesulfonic acid hydrazides yields the corresponding N‐sulfenylmethyl amides.
ChemInform Abstract: Synthesis of Acyl Carbamates via Four Component Pd‐Catalyzed Carbonylative Coupling of Aryl Halides, Potassium Cyanate, and Alcohols.
Authors: Yin Hongfei , de Almeida Angelina M. , de Almeida Mauro V. , Lindhardt Anders T. , Skrydstrup Troels 
Published: July 2015

AbstractThe reactions are carried out in a two chamber system, generating CO from COgen in the first chamber.
ChemInform Abstract: Iron‐Catalyzed Oxidative Biaryl Cross‐Couplings via Mixed Diaryl Titanates: Significant Influence of the Order of Combining Aryl Grignard Reagents with Titanate.
Authors: Liu Kun Ming , Wei Juan , Duan Xin Fang 
Published: July 2015

AbstractFor the first time mixed diaryl titanates are used as intermediates to modify the reactivity of the Grignard reagents.
ChemInform Abstract: Gold(I)‐Catalyzed Cycloisomerizations and Alkoxycyclizations of ortho‐(Alkynyl)styrenes.
Authors: Sanjuan Ana M. , Rashid Muhammad A. , Garcia‐Garcia Patricia , Martinez‐Cuezva Alberto , Fernandez‐Rodriguez Manuel A. , Rodriguez Felix , Sanz Roberto 
Published: July 2015

AbstractThe Au‐catalyzed chiral cycloisomerization of ortho‐(alkynyl)styrenes leads to enantioenriched indenes (II), whilst the similar reaction in the presence of water or methanol affords hydroxy and methoxy derivatives (III) and (V).
ChemInform Abstract: Studies Towards Development of Asymmetric Double‐Mannich Reactions of Chiral 2‐Oxocyclohexanecarboxylate Derivatives with Bis(aminol)ethers.
Authors: Sparrow Kevin John , Carley Sarah , Soehnel Tilo , Barker David , Brimble Margaret A. 
Published: July 2015

AbstractTiCl4 as Lewis acid promoter as well as the (4R,5S)‐4‐methyl‐5‐phenyloxazolidin‐2‐on‐3‐yl moiety as chiral auxiliary show the best results in the title reaction.
ChemInform Abstract: One‐Pot Synthesis of Multisubstituted Butyrolactonimidates: Total Synthesis of (‐)‐Nephrosteranic Acid.
Authors: Wang Huijing , Tang Pei , Zhou Qilong , Zhang Dan , Chen Zhitao , Huang Hongxiu , Qin Yong 
Published: July 2015

AbstractImidates (I) or (IV) and α,β‐unsaturated diesters are subjected to a one‐pot, three‐step cascade reaction to afford the desired lactone structures in a completely diastereoselective manner.
ChemInform Abstract: Bi(OTf)3‐Mediated Cycloisomerization of γ‐Alkynyl Arylketones: Application to the Synthesis of Substituted Furans.
Authors: Chang Meng‐Yang , Cheng Yu‐Chieh , Lu Yi‐Ju 
Published: July 2015

AbstractThe γ‐alkynyl arylketones prepared from the corresponding arylketones by α‐alkylation with propargyl bromides under basic conditions in high yields are efficiently converted to the corresponding substituted furan derivatives under mild reaction conditions.
ChemInform Abstract: Iron‐Catalyzed Tandem Cyclization of Olefinic Dicarbonyl Compounds with Benzylic Csp3—H Bonds for the Synthesis of Dihydrofurans.
Authors: Guo Li‐Na , Wang Shun , Duan Xin‐Hua , Zhou Shi‐Liu 
Published: July 2015

AbstractA highly effective protocol for the synthesis of dihydrofurans through a tandem radical cyclization of olefinic dicarbonyl compounds with benzyl hydrocarbons using iron salt as an environmentally benign catalyst is developed.
ChemInform Abstract: Cu(II)‐Catalyzed Coupling of Aromatic C—H Bonds with Malonates.
Authors: Wang Hong‐Li , Shang Ming , Sun Shang‐Zheng , Zhou Zeng‐Le , Laforteza Brian N. , Dai Hui‐Xiong , Yu Jin‐Quan 
Published: July 2015

AbstractIsoindolines are prepared by oxidative coupling of (oxazolylphenyl)benzamides with malonates using copper catalysis.
ChemInform Abstract: Bifunctional Silver(I) Complex‐Catalyzed CO2 Conversion at Ambient Conditions: Synthesis of α‐Methylene Cyclic Carbonates and Derivatives.
Authors: Song Qing‐Wen , Chen Wei‐Qiang , Ma Ran , Yu Ao , Li Qiu‐Yue , Chang Yao , He Liang‐Nian 
Published: July 2015

AbstractThe Ph3P complex of Ag2CO3, which can be prepared in situ, is found to be a robust bifunctional catalyst for the carboxylative cyclization of propargylic alcohols (I) with CO2.
ChemInform Abstract: Multicomponent Synthesis of Substituted and Fused‐Ring Imidazoles via Phospha‐Muenchnone Cycloaddition.
Authors: Aly Sara , Romashko Mikhail , Arndtsen Bruce A. 
Published: July 2015

AbstractThe reaction of imines (I) with acyl chlorides (II) and 2‐phenyl‐1,3,2‐benzodioxaphosphole followed by reaction of intermediate phospha‐muenchnones with imines (III) leads to a variety of tetrasubstituted imidazoles (IV).
ChemInform Abstract: Synthesis of Oxazolines from Amides via Palladium‐Catalyzed Functionalization of Unactivated C(sp3)—H Bond.
Authors: Li Bo , Wang Si‐Qing , Liu Bin , Shi Bing‐Feng 
Published: July 2015

AbstractOxazolines are prepared from amides by C—H bond activation, chlorination, and nucleophilic cyclization using palladium catalysis.
ChemInform Abstract: Organocatalytic Enantioselective Decarboxylative Reaction of Malonic Acid Half Thioesters with Cyclic N‐Sulfonyl Ketimines by Using N‐Heteroarenesulfonyl Cinchona Alkaloid Amides.
Authors: Nakamura Shuichi , Sano Masahide , Toda Ayaka , Nakane Daisuke , Masuda Hideki 
Published: July 2015

AbstractChiral sultam structures are readily available by the title reaction where the addition of thioester (IV) or analogous reactants such as β‐ketocarboxylic acids (VI) takes place prior to decarboxylation.
ChemInform Abstract: Catalytic Amounts of CBr4 Mediated Dehydrogenative Coupling of Isochromans with Aromatic Ketones.
Authors: Huo Congde , Wu Mingxia , Chen Fengjuan , Jia Xiaodong , Yuan Yong , Xie Haisheng 
Published: July 2015

AbstractA simple procedure is elaborated for the CBr4‐catalyzed oxidative coupling of isochromans (II) and (IV) with aromatic ketones (I).
ChemInform Abstract: Synthesis of New 3‐Carboxamidine Iminocoumarins and Benzopyrano[2,3‐d]pyrimidines.
Authors: Trichili Sihem , Kammoun Myriam , Turki‐Guermazi Hamida , Abid Souhir , Ammar Houcine 
Published: July 2015

AbstractAmong all the tested compounds, iminocoumarin (IIIc) exhibits the greatest AChE inhibitory activity (IC50=0.66 mg/mL).
ChemInform Abstract: Metal‐Free Arylation of Ethyl Acetoacetate with Hypervalent Diaryliodonium Salts: An Immediate Access to Diverse 3‐Aryl‐4(1H)‐quinolones.
Authors: Monastyrskyi Andrii , Namelikonda Niranjan K. , Manetsch Roman 
Published: July 2015

AbstractTreatment of title ester (II) with a series of symmetrical diaryliodonium salts is successful to form the required arylation products.
ChemInform Abstract: Synthesis of Quinolinones with Palladium‐Catalyzed Oxidative Annulation Between Acrylamides and Arynes.
Authors: Wang Weiguo , Peng Xianglong , Qin Xiaoyu , Zhao Xiangyun , Ma Chen , Tung Chen‐Ho , Xu Zhenghu 
Published: July 2015

AbstractThe catalyzed oxidative annulation of electron‐deficient acrylamides with strained benzyne precursors under mild conditions is presented.
ChemInform Abstract: An Efficient Synthesis of Quinolines via Copper‐Catalyzed C—N Cleavage.
Authors: Xi Long‐Yi , Zhang Ruo‐Yi , Zhang Lei , Chen Shan‐Yong , Yu Xiao‐Qi 
Published: July 2015

AbstractA domino C—N cleavage‐cyclocondensation reaction of 2‐aminobenzylamines with various ketones using air as an oxidant efficiently gives quinolines.
ChemInform Abstract: Preparation of 1‐Methyl‐3‐phenylisoquinoline Derivatives from Oximes Using Polyphosphoric Esters.
Authors: Niemczak Michal , Czerniak Kamil , Kopczynski Tomasz 
Published: July 2015

AbstractThe title compounds (II) are synthesized by this new method using the ethyl ester of polyphosphoric acid (PPE) as an efficient reagent.
ChemInform Abstract: Visible Light Mediated Cyclization of Tertiary Anilines with Maleimides Using Nickel(II) Oxide Surface‐Modified Titanium Dioxide Catalyst
Authors: Tang Jian , Grampp Guenter , Liu Yun , Wang Bing‐Xiang , Tao Fei‐Fei , Wang Li‐Jun , Liang Xue‐Zheng , Xiao Hui‐Quan , Shen Yong‐Miao 
Published: July 2015

Abstract30 examples
ChemInform Abstract: Base‐Promoted Transannulation of Heterocyclic Enamines and 2,3‐Epoxypropan‐1‐ones: Regio‐ and Stereoselective Synthesis of Fused Pyridines and Pyrroles.
Authors: Yang Zheng , Hao Wen‐Juan , Xu Hai‐Wei , Wang Shu‐Liang , Jiang Bo , Li Guigen , Tu Shu‐Jiang 
Published: July 2015

AbstractThe microwave‐assisted reaction of N‐aryl 4‐aminofuranones (VI) with epoxypropanones (II) leads to desired furo[3,2‐b]pyridines (VII).
ChemInform Abstract: Synthesis of Pyrrolo[2,1,5‐cd]indolizines Through Dehydrogenative Heck Annelation of Indolizines with Diaryl Acetylenes Using Dioxygen as an Oxidant.
Authors: Hu Huayou , Li Guodong , Hu Weiming , Liu Yun , Wang Xiang , Kan Yuhe , Ji Min 
Published: July 2015

AbstractThe reaction is restricted to diarylacetylenes (II), (XIII), and (XV).
ChemInform Abstract: Synthesis of 6‐(Arylthio)phenanthridines by Copper‐Catalyzed Tandem Reactions of 2‐Biaryl Isothiocyanates with Diaryliodonium Salts.
Authors: Guo Weisi , Li Shoulei , Tang Lin , Li Ming , Wen Lirong , Chen Chao 
Published: July 2015

Abstract(Arylthio)phenanthridines are prepared by tandem C—S/C—C bond—forming reaction of biaryl isothiocyanates with diaryliodonium salts using copper catalysis.
ChemInform Abstract: Tunable Regioselective Synthesis of Pyrazolo[3,4‐d]pyrimidine Derivatives via Aza‐Wittig Cyclization and Dimroth‐Type Rearrangement.
Authors: Wang Tao , Xiong Jun , Wang Wenjuan , Li Rou , Tang Xiaoli , Xiong Fei 
Published: July 2015

AbstractDifferent substituted pyrazolo[3,4‐d]pyrimidine derivatives are efficiently and regioselectively obtained by aza‐Wittig/Ag(I)‐promoted reaction leading to compounds (III) or by base‐promoted tandem reaction leading to compounds (IV).
ChemInform Abstract: Regiospecific Synthesis of Neuroprotective 1,4‐Benzoxazine Derivatives Through a Tandem Oxidation—Diels—Alder Reaction.
Authors: Nguyen Khac Minh Huy , Schwendimann Leslie , Gressens Pierre , Largeron Martine 
Published: July 2015

AbstractCompound (IXa) shows a promising neuroprotective activity in an animal model of excitotoxic lesions in newborn mice.