bluuebunny/crossref_metadata_2025_split huggingface dataset:
Protocol for a feasibility randomised controlled trial of the ‘Outdoor’ mobility intervention for older adults after hip fracture
Authors: Sheehan Katie J. , Bastas Denise , Guerra Stefanny , Creanor Siobhan , Hulme Claire , Lamb Sallie , Martin Finbarr C. , Sackley Catherine , Smith Toby , Bell Philip , Hillsdon Melvyn , Pope Sarah , Cook Heather , Godfrey Emma 
Published: August 2024

Background
A high proportion of patients do not regain outdoor mobility after hip fracture. Rehabilitation explicitly targeting outdoor mobility is needed to enable these older adults to recover activities which they value most. The overarching aim of this study is to determine the feasibility of a randomised controlled trial which aims to assess the clinical- and cost-effectiveness of an intervention designed to enable recovery of outdoor mobility among older adults after hip fracture (the OUTDOOR intervention).

Methods
This is a protocol for a multi-centre pragmatic parallel group (allocation ratio 1:1) randomised controlled assessor-blinded feasibility trial. Adults aged 60 years or more, admitted to hospital from- and planned discharge to- home, with self-reported outdoor mobility in the three-months pre-fracture, surgically treated for hip fracture, and who are able to consent and participate, are eligible. Individuals who require two or more people to support mobility on discharge will be excluded. Screening and consent (or consent to contact) will take place in hospital. Baseline assessment and randomisation will follow discharge from hospital. Participants will then receive usual care (delivered by physiotherapy, occupational therapy, or therapy assistants), or usual care plus the OUTDOOR intervention. The OUTDOOR intervention includes a goal-orientated outdoor mobility programme (supported by up to six in-person visits), therapist-led motivational dialogue (supported by up to four telephone calls), supported by a past-patient led video where recovery experiences are shared, and support to transition to independent ongoing recovery. Therapists delivering the OUTDOOR intervention (distinct from those supporting usual care) will receive training in motivational interviewing and behaviour change techniques. Baseline demographics will be collected. Patient reported outcome measures including health related quality of life, activities of daily living, pain, community mobility, falls related self-efficacy, resource use, readmissions, and mortality will be collected at baseline, 6-weeks, 12-weeks, and 6-months (for those enrolled early in the trial) post-randomisation. Exercise adherence (6- and 12- weeks) and intervention acceptability (12-weeks) will be collected. A subset of 20 participants will also support accelerometery data collection for 10 days at each time point.

Dissemination
The trial findings will be disseminated to patients and the public, health professionals and researchers through publications, presentations and social media channels.

Trial registration
The trial has been registered at ISRCTN16147125.

Protocol version
3.0.
Rural suicide in Newfoundland and Labrador: A qualitative exploration of health care providers’ perspectives
Authors: Pritchard Tyler R. , Buckle Jennifer L. , Thomassin Kristel , Lewis Stephen P. 
Published: August 2024

Introduction
Residents of rural regions may have higher and unique suicide risks. Newfoundland and Labrador (NL) is a Canadian province replete with rural regions. Despite an abundance of rural suicide research, heterogeneity in rural regions may preclude amalgamating findings to inform prevention efforts. Thus, exploring the unique needs of NL is needed. Importantly, health care providers (HCP) may afford unique perspectives on the suicide-related needs or concerns of rural life. We asked HCPs of residents of rural NL their perceived suicide risk factors, concerns, and needs for rural NL.

Method
Twelve HCPs of rural residents of NL completed virtual semi-structured interviews. Interviews were analysed using reflexive thematic analysis [13,14].

Results
HCPs noted individual, psychological, social, and practical factors linked to rural-suicide risk and subsequent needs. Findings highlight the unique challenges of residing and providing health care in rural NL and inform prevention and intervention efforts.
Terror in the City: Local Terrorism and Firm Exports
Authors: Bönte Werner , Procher Vivien D. , Malik Faisal S. 
Published: August 2024

Abstract
In this paper, we examine the relationship between terrorism and exports at the firm-level. We use a panel data of 301 firms listed on the Pakistan Stock Exchange and records of terrorist attacks in Pakistani cities from 1999 to 2014. By calculating city-level terrorism indices, the study reveals significant variations in the frequency of terrorist incidents both between cities and within cities over different time periods. Our panel regressions show that firm exports are correlated with terrorist attacks in the cities where the firms are located, and these correlations are statistically significant even when terrorism is lagged up to six years. Interregional spillover effects of terrorism are less pronounced. While a negative correlation can be found between firm exports and our terrorism indices, the correlation with domestic sales tends to be statistically insignificant. The findings shed light on the persistent link between local terrorism and firms’ international and domestic operations.
Bayesian bivariate Conway–Maxwell–Poisson regression model for correlated count data in sports
Authors: Florez Mauro , Guindani Michele , Vannucci Marina 
Published: August 2024

Abstract
Count data play a crucial role in sports analytics, providing valuable insights into various aspects of the game. Models that accurately capture the characteristics of count data are essential for making reliable inferences. In this paper, we propose the use of the Conway–Maxwell–Poisson (CMP) model for analyzing count data in sports. The CMP model offers flexibility in modeling data with different levels of dispersion. Here we consider a bivariate CMP model that models the potential correlation between home and away scores by incorporating a random effect specification. We illustrate the advantages of the CMP model through simulations. We then analyze data from baseball and soccer games before, during, and after the COVID-19 pandemic. The performance of our proposed CMP model matches or outperforms standard Poisson and Negative Binomial models, providing a good fit and an accurate estimation of the observed effects in count data with any level of dispersion. The results highlight the robustness and flexibility of the CMP model in analyzing count data in sports, making it a suitable default choice for modeling a diverse range of count data types in sports, where the data dispersion may vary.
Selfhood Beyond Death
Authors: Schermbrucker Ben 
Published: August 2024

Abstract
There is a strong secular consensus that death terminates subjective consciousness. In this paper I show that this consensus can be meaningfully doubted for entirely secular reasons. After formulating the strongest possible argument which supports this consensus, I argue that it inconsistently excludes Constitutive Russellian Panpsychism (CRP) from consideration. CRP, I maintain, is fully consistent with the possibility of post-thanatological consciousness. To flesh out this account, I develop an account of the Panpsychist Self (PS) that can be axiomatically derived from CRP. I then show that the PS has the right metaphysical structure to ensure that the persistence of consciousness beyond brain death aligns with the persistence of our individual selves.
The crystal structure of ethyl (Z)-2-(ethoxymethylene)-3-oxobutanoate, C9H14O4
Authors: Hentsch Andreas , Merzweiler Kurt 
Published: August 2024

Abstract
C9H14O4, monoclinic, P21/n (no. 14), a = 8.9332(5) Å, b = 6.8170(2) Å, c = 17.0530(9) Å, β = 102.816(4)°, V = 1,012.62(8) Å3, Z = 4, R[F
2 > 2σ(F
2)] = 0.0363, wR(F
2) = 0.1046, T = 170 K.
The kinetic relativity theory – hiding in plain sight
Authors: Loen Mark V. 
Published: August 2024

Abstract
A question in physics is whether Special Relativity (SR) is the only theory that explains relativistic behavior. SR measures time dilation by a relative velocity between two frames. Laboratory experiments with a single moving body fit this concept. However, GPS satellites and their ground clocks measure time dilation by a velocity relative to a common non-rotating Earth inertial frame. To better understand the conceptual difference, an experimental survey was undertaken. The survey analysis showed that laboratory experiments also fit into the non-rotating Earth frame concept. The laboratory experiments only need to add the Earth rotational velocity to both the laboratory frame and the moving frame. The analysis also revealed that the relative velocity calculation was astonishingly close to the common Earth frame calculation. The common Earth frame then becomes the explanation for all experimental types. And it signifies that a gravity field – moving body interaction causes relativistic effects. The experimental record also contained enough data to draft an empirical kinetic theory different than SR. The “no preferred reference frame” of SR is replaced by “there is a preferred reference frame.” And the preferred frame is the nearby Earth gravity field.
Polyimide strengthened cement mortar
Authors: Poyraz Bayram , Dayi Mustafa 
Published: August 2024

Abstract
This study examined the effects of silane-modified polyimide polymer (PIS) on cement mortar. The PIS was added to replace cement in a specified ratio. Obtained results revealed that the PIS caused retardation on setting time, and accelerated UPV mostly by encapsulating unhydrated cement particles, filling pores, or reacting with C–S–H and Ca(OH)2 with shifting to Si–O vibrations. SEM results showed a good compact interface without forming considerable agglomeration and voids on the microstructure, and this improved flexural and compressive strength properties. In conclusion, silane-modified polyimide as an admixture or cement replacement can be recommended for construction industries to enhance the properties of cement mortar.
Elucidating metformin action on the ovary and fertility in healthy mice
Authors: Velazquez Candela , Bordaquievich Mayra , Herrero Yamila , Cohen Débora Juana , Bianchi María Silvia , Cuasnicu Patricia , Prost Katherine , Pascuali Natalia , Parborell Fernanda , Abramovich Dalhia 
Published: August 2024

In brief
The hypoglycemic drug metformin has shown reproductive effects in women, although its mechanism of action is not fully understood. In this study, we demonstrate the direct effects of metformin on the ovary of healthy mice, with no alterations in fertility.

Abstract
Metformin is a hypoglycemic drug widely used in type-2 diabetes (T2D) patients. In recent years, this drug has been suggested as a treatment for gestational diabetes and recommended to women with ovarian hyperstimulation syndrome (PCOS) to increase the chances of pregnancy or avoid early miscarriages. However, the exact effects of metformin on the female reproductive tract in general, and on the ovary in particular, are still not completely understood. In this study, we analyzed the effect of metformin on fertility and ovarian physiology in healthy female mice. We found that this drug altered the estrous cycle, early follicular development, serum estradiol and progesterone levels, and ovarian steroidogenic enzyme expression. Moreover, ovarian angiogenesis was lower in metformin-treated animals compared with untreated ones, whereas natural or gonadotropin-induced fertilization rates remained unchanged. However, offspring of metformin-treated animals displayed decreased body weight at birth. In this work, we unraveled the main effects of metformin on the ovary, isolated from other conditions such as hyperglycemia and hyperandrogenism, which is essential for a better understanding of metformin’s mechanisms of action on reproduction and fertility.
Implementation of the School as a Learning Organisation Approach in Vocational Education: The Case of Latvia
Authors: Siliņa-Jasjukeviča Gunta , Briška Ilze , Lūsēna-Ezera Inese , Lastovska Agnese , Linde Inga 
Published: August 2024

Context. Recent studies recognise that the use of the School as a Learning Organisation (SLO) approach in educational management is the key factor ensuring a general education institution’s ability to effectively implement the education policy goals and adapt to change as the use of SLO. Although vocational education has different predominant goals and different target groups, likewise general education, it is exposed to dynamic change and new challenges.Purpose. Within the framework of the study, it was researched whether and how SLO can be applied in vocational education as the use of SLO facilitates a high level of professional competence of the management and academic staff, enhances common strategic vision, responsibility and autonomy, diverse collaboration, effective resource management, and the dissemination of knowledge and good practice, which are also important in vocational education.Methods. Using qualitative data analysis, the paper analyses the experience of EU and OECD countries in the implementation of SLO in vocational education and identifies, which dimensions of the SLO model are represented in the policy and practice of vocational education in Latvia. In the focus group interviews with representatives of vocational education institutions of Latvia, the characteristics of the SLO approach in vocational education were studied, challenges were described and solutions proposed for the targeted implementation of the SLO approach in vocational education in Latvia.Results. All 7 dimensions of the SLO can be found in the education policy documents of the EU and OECD countries and Latvia, as well as in the focus group interviews, which shows that there is a gradual progress towards the transformation of vocational education institutions into learning organisations.Conclusions. For education policy makers: Since the features of SLO are only partially visible in vocational education documents in Latvia, the framework should be improved to cover all dimensions of the SLO, and norms and agreements on collective understanding should be harmonised in policy documents. For school representatives: Raise awareness of the staff of vocational education institutions of the essence of the SLO and its role in improving the quality of education and ensure that all dimensions of SLO are understood and addressed appropriately. For entrepreneurs: Help define the diverse, varied manifestations of professions in the sector in order to engage the individual potential of learners as effectively as possible. For researchers: Help find ways to resolve controversies by identifying good practice and research.
Estandarización de una prueba de ELISA para detección de anticuerpos contra el herpesvirus bovino -1 en suero lácteo
Authors: Rodas Juan David , Zuluaga Fabio N , Henao Guillermo , Restrepo Martín , Ossa L Jorge E 
Published: August 2024

Resumen El presente estudio tuvo por objeto estandarizar una prueba de ELISA en suero lácteo para optimizar la aplicación de esta técnica a la caracterización de la Rinotraqueitis Infecciosa Bovina (RIB). Se tomaron, para el efecto, 69 muestras de suero lácteo de animales positivos por neutralización y ELISA en suero sanguíneo y 105 de animales negativos por ambas pruebas. El valor promedio de los delta de densidad óptica (diferencia de promedios entre los pozos con antígeno y con control de antígeno) para los 105 sueros negativos fue de 0,04 con una desviación estándar de 0,02 y para los 69 positivos fue de 0,20 con una desviación estándar de 0,06. Con base en estos datos se determinó un punto de corte de 0,08 con el cual se logra una sensibilidad del 100% y una especificidad del 94%. La concordancia de los resultados entre las pruebas para los dos tipos de muestras fue del 97%. Estos resultados aportan un elemento más para la caracterización y el control o erradicación de esta enfermedad en el país. Finalmente se discute la importancia de optimizar aún mas esta prueba, mediante el uso de leche entera y de "pooles" de suero lácteo, que permitirían la aplicación de la prueba a estudios masivos de tamizaje en grandes poblaciones Summary The objective of this study was to standardize an ELISa technique for serological testing of BHV-1 in milk serum. This technique is expected to facilitate large serological screening in milking cows. For this purpose, 69 samples from Nt and ELISA positives and 105 Nt and ELISA negatives animals were used. The average of optical densities for the negative samples was 0.04 +/- 0.02 and for the positive the averge was 0.20 +/- 0.06 based on this results we set a delta value of optical density of 0.08 as the cut off point for positivity. This value gives a sensibility of 100% and specificity of 94%. The concordance between serum Nt and serum ELISA and milk serum ELISA was of 97%. The standardization of this ELISA provides a new instrument not only for the characterization of the infection in our country but also for its control and eventual eradication. Finally we discuss the possibility of further optimizing by using straight milk or milk serum pools to facilitate further the massive screening of large populations.
Estandarización de una técnica de reacción en cadena de polimerasa (PCR) para detección de Herpesvirus bovino-1 en semen
Authors: Rodas Juan David , Zuluaga Fabio N , Ossa Jorge E 
Published: August 2024

Resumen El HVB-1 puede extraerse en semen de animales seropositivos pero la frecuencia de excreción y el impacto de esta vi de transmisión no han sido aclaradas. Para contribuir a esta discusión se hizo un esfuerzo por estandarizar una prueba de PCR para HVB-1 en semen. Como otros autores lo habían informado, encontramos que el semen contiene factores inhibidores de la reacción que hacen que, cuando no se trabaja con DNA purificado, sea necesaria la dilución de la muestra hasta 1:6000 para poder lograr la amplificación del DNA viral. Con el objetivo de amentar la posibilidad de detección de la banda de DNA viral esperada, se utilizó un Southern Blot con una sonda obtenida a partir del poli nucleótido amplificado por los cebadores respectivos, marcada con P32. Los ensayos preliminares muestran un nivel de detección 100 veces mayor. A pesar de la alta dilución de la muestra de semen que reduce notoriamente la posibilidad de detección del PCR, esta prueba permitió la detección del virus en muestras de campo procedentes de un brote de enfermedad compatible con RIB. La prueba de PCR para la detección del HVB-1 en semen podría tener su mayor impacto en el control de calidad de programas de congelación de semen, inseminación artificial y transferencia de embriones; adicionalmente podría ser de utilidad para definir el verdadero impacto de esta vía de transmisión Summary BHV-1 can be found in semen from seropositive animals, but the frequency of excretion and the impact of this route for the dissemination of the infection have not been established. In order to improve the sensibility of detection of the virus in semen, we attempted to standardize a PCR. As previously reported by others investigators we found that semen contains PCR inhibitory factors that makes it necessary to dilute the samples up to 1:6000 or more to obtain DNA amplification. With the purpose of increasing the sensibility of the assay, the amplified PCR product was detected by southern blot with an oligonucleotide probe internal to the amplified fragment, Preliminary assays showed a 100 fold increase in the sensibility with this strategy. Despite the high dilution of the semen sample, we could detected the virus in samples collected from bulls from herds with symptoms compatible with Infectious Bovine Rinotracheitis (IBR). This PCR could be used in quality control of specimens used in programs of artificial insemination and embryo transfer. In addition, it could be of used for the determination of the biological implications of this route of virological excretion.
Evaluación de los Microorganismos eficaces (E.M) en producción de abono orgánico a partir del estiércol de aves de jaula
Authors: Uribe José F. , Estrada P. Mónica M. , Córdoba Santiago , Hernández Luis E. , Bedoya Diana M. 
Published: August 2024

Resumen En este estudio se evaluó el proceso de compostaje de gallinaza de aves de jaula y el efecto de los Microorganismos Eficaces (EM) sobre la composición física y química del compost. La metodología empleada considera un proceso aeróbico mediante la remoción del material mecánicamente, se tomaron muestras semanales para mediciones de humedad y pH, al final del proceso se realizaron análisis químico para determinar la calidad del producto. Se trabajó bajo un diseño irrestrictamente al azar (DIA) con un grupo testigo y dos tratamientos con cinco réplicas para cada uno, mezcla de gallinaza + aserrín más microorganismos eficaces una sola vez y mezcla de gallinaza +aserrín en proporción 1 :1+E M. El proceso de compostación se produjo de la segunda a la cuarta semana y el secado de la quinta a la sexta semana para todos los tratamientos; sin embargo la mezcla de la gallinaza con EM, presentó una diferencia estadísticamente significativa (p < 0.05) con respecto a la formulación de gallinaza, aserrín y EM en pH, mostrando un descenso más rápido, por debajo de 8.5, lo cual indica una aceleración en el proceso de estabilización del compost. Las pruebas físico-químicas realizadas al final muestran mayores valores de Nitrógeno y Potasio para la mezcla de gallinaza con EM. Los valores en la relación Carbono/Nitrógeno y en la Capacidad de Intercambio catiónico, fueron adecuados para este tipo de compostajes en los tres tratamientos. Palabras clave: abonos orgánicos, compost, compostaje, estiércol, gallinaza. Summary An evaluation of the transformation process of caged hens' dung into organic fertilizer, was carried out in this study in order to recognize the performance of efficient microorganisms (EM) upon the physical and chemical composition of the compost. The used methodology considers an aerobic process by means of mechanical removal of the material, weekly samples were taken for humidity and pH measurements, at the end of the process analysis to determine the products quality were done. The work was done under a random unrestricted design (RUD) with a control group and two treatments, five replicas for each one. According to the results the process of compost formation was produced between the second and fourth week and the drying from the fifth to the sixth week for al¡ the treatments. The mixture of the manure and the EM however, showed a statistically significant difference (p < 0.05) in pH with regard to the other treatments, showing a faster descent (below 8.5), which indicates the positive effect in the acceleration of the compost stabilization process with the addition of EM. The physical and chemical tests carried out at the end show greater values of nitrogen and potassium for the mixture of hens' dung and EM. Key words: bio process, compostage, compost, hens' dung.