bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ferrocene‐Based Planar Chiral Imidazopyridinium Salts for Catalysis
Authors: Check Christopher T. , Jang Ki Po , Schwamb C. Benjamin , Wong Alexander S. , Wang Michael H. , Scheidt Karl A. 
Published: January 2015

AbstractPlanar chirality remains an underutilized control element in asymmetric catalysis. Factors that have limited its broader application in catalysis include poor catalyst performance and difficulties associated with the economical production of enantiopure planar chiral compounds. The construction of planar chiral azolium salts that incorporate a sterically demanding iron sandwich complex is now reported. Applications of this new N‐heterocyclic carbene as both an organocatalyst and a ligand for transition‐metal catalysis demonstrate its unprecedented versatility and potential broad utility in asymmetric catalysis.
λ‐Orthogonale Photochemie: Lichtinduzierte pericyclische Reaktionen an Makromolekülen
Authors: Hiltebrandt Kai , Pauloehrl Thomas , Blinco James P. , Linkert Katharina , Börner Hans G. , Barner‐Kowollik Christopher 
Published: January 2015

AbstractEine photochemische Strategie nutzt λ‐orthogonale Reaktionen zum Aufbau makromolekularer Architekturen und zum wellenlängenabhängigen Einbau chemischer Funktionalitäten in ein einzelnes Molekül. λ‐Orthogonale pericyclische Reaktionen können unabhängig voneinander durch die spezifische photochemische Aktivierung einer chemischen Funktionalität ablaufen. Die Leistungsfähigkeit dieses neuen Konzeptes wird durch eine Eintopfreaktion belegt, bei der Maleinsäureimid mit zwei Polymeren, die unterschiedliche photoaktive Endgruppen (Photoenol und Tetrazol) tragen, selektiv reagieren. Beliebige aktivierte Doppelbindungen können durch eine gezielte Bestrahlung mit λ=310–350 nm mit einem Photoenol‐funktionalisierten Polymer reagieren. Nach vollständigem Photoenolumsatz aktiviert eine Bestrahlung mit λ=270–310 nm die Reaktion des Tetrazols mit Maleimid. Die Vielseitigkeit dieses Ansatzes wird durch die λ‐orthogonale Klick‐Reaktionen von komplexen Maleimiden, funktionalen Enen und Polymeren an ein zentrales Polymergerüst gezeigt.
Structure Determination of [Au18(SR)14]
Authors: Das Anindita , Liu Chong , Byun Hee Young , Nobusada Katsuyuki , Zhao Shuo , Rosi Nathaniel , Jin Rongchao 
Published: January 2015

AbstractUnravelling the atomic structures of small gold clusters is the key to understanding the origin of metallic bonds and the nucleation of clusters from organometallic precursors. Herein we report the X‐ray crystal structure of a charge‐neutral [Au18(SC6H11)14] cluster. This structure exhibits an unprecedented bi‐octahedral (or hexagonal close packing) Au9 kernel protected by staple‐like motifs including one tetramer, one dimer, and three monomers. Until the present, the [Au18(SC6H11)14] cluster is the smallest crystallographically characterized gold cluster protected by thiolates and provides important insight into the structural evolution with size. Theoretical calculations indicate charge transfer from surface to kernel for the HOMO–LUMO transition.
Small vessels and long lesions
Authors: Srour John Fani , Abbott J. Dawn 
Published: January 2015

Key Points

Small vessels (SV) and long lesions (LL) are associated with a relatively high rate of adverse outcomes even in the drug eluting stent (DES) era.
The current study shows very low rates of target vessel failure in SV and LL cohorts treated with the platinum chromium everolimus‐eluting stent (PtCr‐EES).
Further investigation directly comparing newer DES in these subsets is needed.
A Green Strategy to Enhance a Liquid–Liquid Heterogeneous Reaction with a Magnetic Recyclable Pickering Emulsion
Authors: Feng Linbin , Wang Jianli , Chen Liang , Lu Meizhen , Zheng Zhi , Jing Ren , Chen Hualiang , Shen Xianbo 
Published: January 2015

AbstractThis work described a general strategy to enhance a typical organic–aqueous heterogeneous green oxidation reaction by introducing surface tunable magnetic nanoparticles into liquids to form a controllable Pickering emulsion. We synthesized cross‐linked polystyrene (PS)‐covered Fe3O4 nanoparticles grafted with different N‐alkyl imidazoles and systematically discussed the effect of surface properties on the formation of emulsions. By loading such particles, the dichloromethane–water‐based 2,2,6,6‐tetramethylpiperidine‐1‐oxyl‐mediated Montanari oxidation system was converted from the unstable millimeter‐scale dispersion into a stable micrometer‐scale emulsion, which significantly reduced the reactant transfer distance and resulted in a significantly high overall reaction rate. This reaction efficiency is elucidated in terms of unique properties inherent in an emulsion, including the self‐assembly of Fe3O4/PS and Fe3O4/PS[im‐Cn]Cl (n=1, 4, 6, and 10) nanoparticles, well ensuring a large specific surface area of the water–oil interface.
Effects of Thickness and Grafting Density on the Activity of Polymer‐Brush‐Immobilized Tris(triazolyl) Copper(I) Catalysts
Authors: Fernandes Antony E. , Ye Qian , Collard Laurent , Le Duff Cécile , d'Haese Cécile , Deumer Gladys , Haufroid Vincent , Nysten Bernard , Riant Olivier , Jonas Alain M. 
Published: January 2015

AbstractWe report herein the application of polymer brushes for the immobilization of tris[(1,2,3‐triazolyl)methyl]amine CuCl catalysts. Well‐defined catalytic brushes were prepared through grafting‐from and postpolymerization modification approaches on Si surfaces and characterized by X‐ray reflectivity, X‐ray photoelectron spectroscopy, and inductively coupled plasma mass spectrometry. Hairy catalysts of varying thickness and grafting density were investigated in a model CuI‐catalyzed azide–alkyne cycloaddition reaction and showed remarkable activity at loadings as low as 0.02 mol % as a result of the unique catalytic site density and nuclearity found in the brush. We demonstrate that thickness and grafting density parameters can be adjusted to maximize catalytic activity along the brush thickness.
Natural Abundance 15N NMR by Dynamic Nuclear Polarization: Fast Analysis of Binding Sites of a Novel Amine‐Carboxyl‐Linked Immobilized Dirhodium Catalyst
Authors: Gutmann Torsten , Liu Jiquan , Rothermel Niels , Xu Yeping , Jaumann Eva , Werner Mayke , Breitzke Hergen , Sigurdsson Snorri T. , Buntkowsky Gerd 
Published: January 2015

AbstractA novel heterogeneous dirhodium catalyst has been synthesized. This stable catalyst is constructed from dirhodium acetate dimer (Rh2(OAc)4) units, which are covalently linked to amine‐ and carboxyl‐bifunctionalized mesoporous silica (SBA‐15NH2COOH). It shows good efficiency in catalyzing the cyclopropanation reaction of styrene and ethyl diazoacetate (EDA) forming cis‐ and trans‐1‐ethoxycarbonyl‐2‐phenylcyclopropane. To characterize the structure of this catalyst and to confirm the successful immobilization, heteronuclear solid‐state NMR experiments have been performed. The high application potential of dynamic nuclear polarization (DNP) NMR for the analysis of binding sites in this novel catalyst is demonstrated. Signal‐enhanced 13C CP MAS and 15N CP MAS techniques have been employed to detect different carboxyl and amine binding sites in natural abundance on a fast time scale. The interpretation of the experimental chemical shift values for different binding sites has been corroborated by quantum chemical calculations on dirhodium model complexes.
ChemInform Abstract: Thermochromism in Yttrium Iron Garnet Compounds.
Authors: Serier‐Brault Helene , Thibault Lucile , Legrain Magalie , Deniard Philippe , Rocquefelte Xavier , Leone Philippe , Perillon Jean‐Luc , Le Bris Stephanie , Waku Jean , Jobic Stephane 
Published: January 2015

AbstractThe compounds Y3Fe5O12 and Y3Fe5‐xCrxO12 are synthesized by solid state reaction of stoichiometric mixtures of Y2O3, Fe2O3, and Cr2O3 (air, 1350 °C, 6 h).
ChemInform Abstract: Superparamagnetism, Magnetoresistance and Anomalous Hall Effect in Amorphous MnxSi1‐x Semiconductor Films.
Authors: Xiao Shu‐qin , et al. et al. 
Published: January 2015

AbstractMn0.48Si0.52 semiconductor films are prepared by co‐sputtering from high‐purity Mn and Si targets on glass substrates (20 °C, 10 mTorr argon).
ChemInform Abstract: Aminopolycarboxylate Bismuth(III)‐Based Heterometallic Compounds as Single‐Source Molecular Precursors for Bi4V2O11 and Bi2CuO4 Mixed Oxides.
Authors: Whitmire Kenton H. , et al. et al. 
Published: January 2015

AbstractCompounds (IV), (V), (VI), (VIII), and (X) are prepared as single‐source precursors for Bi4V2O11 and Bi2CuO4 mixed oxides, and the crystal structures of (IV), (VI), (VIII), and (X) are determined by single crystal XRD.
ChemInform Abstract: Sr3Bi2(SeO3)6·H2O: A Novel Anionic Layer Consisting of Second‐Order Jahn—Teller (SOJT) Distortive Cations.
Authors: Ahn Hyun Sun , Lee Eun Pyo , Chang Hong‐Young , Lee Dong Woo , Ok Kang Min 
Published: January 2015

AbstractSingle crystals of the title compound are grown by hydrothermal reaction of SrCO3, Bi2O3, and SeO2 in the molar ratio 3:5:6 (H2O, autoclave, 230 °C, 4 d; 77% yield).
ChemInform Abstract: 1D Heterometallic Oxalate Compounds as Precursors for Mixed Ca—Cr Oxides — Synthesis, Structures, and Magnetic Studies.
Authors: Andros Lidija , Juric Marijana , Popovic Jasminka , Pajic Damir , Zadro Kreso , Molcanov Kresimir , Zilic Dijana , Planinic Pavica 
Published: January 2015

AbstractThe single‐source precursors (IV) for the formation of Ca—Cr oxides are characterized by single crystal XRD, magnetic measurements, and IR spectroscopy.
ChemInform Abstract: Stereoselective Aminoxylation of Biradical Titanium Enolates with TEMPO.
Authors: Gomez‐Palomino Alejandro , Pellicena Miquel , Romo Juan Manuel , Sola Ricard , Romea Pedro , Urpi Felix , Font‐Bardia Merce 
Published: January 2015

AbstractConversion of chiral N‐acyl‐4‐benzyl‐oxazolidinones (I) to titanium enolates and subsequent quenching with TEMPO results in an efficient formation of 2‐aminoxylation adducts in excellent yields and good enantioselectivities.
ChemInform Abstract: Iridium(I) Hydroxides in Catalysis: Rearrangement of Allylic Alcohols to Ketones.
Authors: Nelson David J. , Fernandez‐Salas Jose A. , Truscott Byron J. , Nolan Steven P. 
Published: January 2015

AbstractAn iridium(I) hydroxide complex catalyzes the rearrangement of allylic alcohols to ketones.
ChemInform Abstract: Buchwald—Hartwig Amination Approach for the Synthesis of Functionalized 1,2,3,4‐Tetrahydroacridine Derivatives.
Authors: de Sousa Julien , Brown Richard C. D. , Baati Rachid 
Published: January 2015

AbstractThe synthesis of a series of functionalized tacrines by using a microwave‐assisted Buchwald—Hartwig amination reaction is described.
ChemInform Abstract: Coupling of Titanacyclopentadienes with a Cp Ligand and Elimination of One Substituent.
Authors: Mizukami Yuki , Li Haijun , Nakajima Kiyohiko , Song Zhiyi , Takahashi Tamotsu 
Published: January 2015

AbstractTrisubstituted indenes are formed from alkynes and Cp2TiCl2 via titanacyclopentadienes in the presence of trimethylphosphine and azobenzene.
ChemInform Abstract: Rapid Access to β‐Trifluoromethyl‐Substituted Ketones: Harnessing Inductive Effects in Wacker‐Type Oxidations of Internal Alkenes.
Authors: Lerch Michael M. , Morandi Bill , Wickens Zachary K. , Grubbs Robert H. 
Published: January 2015

AbstractThe title procedure under conditions A) renders possible a rapid and successful access to the desired ketones.
ChemInform Abstract: Hyperbranched Polyamines: Tunable Catalysts for the Henry Reaction.
Authors: Ganesan Subramaniapillai Selva , Ganesan Asaithampi , Kothandapani Jagatheeswaran 
Published: January 2015

AbstractThe synthesis of the catalysts (Ia,b) and the recyclability of (Ia) is described.
ChemInform Abstract: Palladium‐Catalyzed C‐H Acylation of Arenes Using Thioethers as Directing Groups.
Authors: Xu Bo , Liu Wei , Kuang Chunxiang 
Published: January 2015

AbstractA convenient protocol for the synthesis of diaryl ketones through Pd‐catalyzed direct ortho‐acylation of benzylmercaptans using α‐oxocarboxylic acids is presented.
ChemInform Abstract: A Broensted Acid Catalyzed Redox Arylation.
Authors: Peng Bo , Huang Xueliang , Xie Lan‐Gui , Maulide Nuno 
Published: January 2015

AbstractThe metal‐free procedure can be applied to various aryl sulfoxides and ynamides bearing a terminal oxazolidone to afford α‐arylated acyl compounds in a redox‐neutral, atom‐economic fashion.
ChemInform Abstract: Enantioselective Construction of Quaternary Stereogenic Carbon Atoms by the Lewis Base Catalyzed Additions of Silyl Ketene Imines to Aldehydes.
Authors: Denmark Scott E. , Wilson Tyler W. , Burk Matthew T. 
Published: January 2015

AbstractThe presented reaction gives alcohols bearing quaternary stereocenters in high yields and excellent diastereo‐ and enantioselectivities tolerating a broad scope of aliphatic and aromatic substituents on both, the aldehyde and ketene imine.
ChemInform Abstract: Pd‐Catalyzed Synthesis of 9,9′‐Bifluorenylidene Derivatives via Dual C—H Activation of Bis‐biaryl Alkynes.
Authors: Zhao Jian , Asao Naoki , Yamamoto Yoshinori , Jin Tienan 
Published: January 2015

AbstractThe combination of MnO2 with PivOH/PdCl2 is found to be optimal for the preparation of the title compounds with a broad spectrum of functionalities.
ChemInform Abstract: Asymmetric Diastereoselective Synthesis of Spirocyclopropane Derivatives of Oxindole.
Authors: Oseka Maksim , Noole Artur , Zari Sergei , Oeeren Mario , Jaerving Ivar , Lopp Margus , Kanger Tonis 
Published: January 2015

AbstractThe title reaction is based on the Michael addition of 3‐chlorooxindole (I) to unsaturated 1,4‐dicarbonyl compounds (II) and (IV), followed by an intramolecular nucleophilic substitution.
ChemInform Abstract: Thermolysis of 4‐Diazotetrahydrofuran‐3‐ones: Total Change of Reaction Course Compared to Photolysis.
Authors: Rodina Ludmila L. , Medvedev Jury J. , Galkina Olesia S. , Nikolaev Valerij A. 
Published: January 2015

AbstractThe title reaction furnishes 2,2,4,5‐substituted 3(2H)‐furanones as a result of 1,2‐alkyl (aryl) shift.
ChemInform Abstract: Base‐Catalyzed Domino Michael—Alkylation—Rearrangement Reaction: A Synthetic Route to Functionalized 2,3‐Dihydrofurans.
Authors: Zhang Ren‐Zun , Meng Chang‐Yu , Xie Jian‐Wu , Xu Mei‐Lan , Zhu Wei‐Dong 
Published: January 2015

Abstract2,3‐Dihydrofurans are formed from acetyl‐derived 2‐halo‐1,3‐dicarbonyl compounds and dienes in the presence of potassium hydroxide.
ChemInform Abstract: Access to 3‐Arylindoles Through a Tandem One‐Pot Protocol Involving Dearomatization, a Regioselective Michael Addition Reaction, and Rearomatization.
Authors: Chittimalla Santhosh Kumar , Bandi Chennakesavulu , Putturu Sireesha , Kuppusamy Rajesh , Boellaard Kevin Christopher , Tan David Chu Aan , Lum Demi Ming Jie 
Published: January 2015

AbstractOxidation of 2‐methoxy phenol derivatives in the presence of methanol provides dearomatized oxygenated intermediates.
ChemInform Abstract: Catalyst‐Free One‐Pot Tandem Reduction of Oxo and Ene/Yne Functionalities by Hydrazine: Synthesis of Substituted Oxindoles from Isatins.
Authors: Jha Mukund , Shelke Ganesh M. , Kumar Anil 
Published: January 2015

AbstractAn unique one‐pot, catalyst‐free tandem reduction of oxo and ene/yne functionalities of substituted isatins is disclosed for the synthesis of oxindole derivatives.
ChemInform Abstract: Synthesis of 3‐Aryl‐1H‐indazoles via Iridium‐Catalyzed C—H Borylation and Suzuki—Miyaura Coupling.
Authors: Egan Ben A. , Burton Paul M. 
Published: January 2015

AbstractBoronic esters, prepared by iridium‐catalyzed regioselective C3‐borylation undergo Suzuki—Miyaura coupling with various aryl halides to afford the corresponding 3‐arylated products.
ChemInform Abstract: Rhodium(III)‐Catalyzed Regioselective C2‐Amidation of Indoles with N‐(2,4,6‐Trichlorobenzoyloxy)amides and Its Synthetic Application to the Development of a Novel potential PPARγ Modulator.
Authors: Shi Jingjing , Zhao Guanguan , Wang Xiaowei , Xu H. Eric , Yi Wei 
Published: January 2015

AbstractThe first direct regioselective C2‐amidation of pyrimidyl‐protected indoles is presented.
ChemInform Abstract: Metal‐Templated Enantioselective Enamine/H‐Bonding Dual Activation Catalysis.
Authors: Huo Haohua , Fu Chen , Wang Chuanyong , Harms Klaus , Meggers Eric 
Published: January 2015

AbstractThe Ir(III) complex IRC constitutes one of the most efficient catalyst for the enantioselective α‐amination of aldehydes with catalyst loadings down to 0.1 mol%.
ChemInform Abstract: Sulfur—Carbon Bond Formation Through Ring‐Opening of Triazolothiadiazole with Organometallics.
Authors: Othman Raja Ben , Massip Stephane , Marchivie Mathieu , Jarry Christian , Vercouillie Johnny , Chalon Sylvie , Guillaumet Gerald , Suzenet Franck , Routier Sylvain 
Published: January 2015

AbstractS‐substituted thiotriazoles are formed from triazolothiadiazoles and arylcuprates, Grignard‐reagents and organolithium compounds.
ChemInform Abstract: Cascade Michael—Intramolecular Transesterification—Elimination Reaction of 3,4‐Dihydro‐3‐nitrochromen‐2‐ones and β,γ‐Unsaturated α‐Oxo Esters: An Efficient Access to 2‐Pyrone Derivatives.
Authors: Zhang Li , Wang Youming , Song Haibin , Zhou Zhenghong , Tang Chuchi 
Published: January 2015

AbstractA new and efficient method for the preparation of 2‐oxopyrone‐6‐carboxylates under mild conditions is described.
ChemInform Abstract: Catalyst‐Free Cascade Reaction of Heterocyclic Ketene Aminals with N‐Substituted Maleimide to Synthesise Bicyclic Pyrrolidinone Derivatives.
Authors: Liu Jin , Zhang Hai‐Rui , Lin Xin‐Rong , Yan Sheng‐Jiao , Lin Jun 
Published: January 2015

AbstractThe title reaction provides a facile access to a wide variety of bicyclic pyrrolidine derivatives.
ChemInform Abstract: Ligand‐Free MCR for Linking Quinoxaline Framework with a Benzimidazole Nucleus: A New Strategy for the Identification of Novel Hybrid Molecules as Potential Inducers of Apoptosis.
Authors: Sunke Rajnikanth , Babu P. Vijaya , Yellanki Swapna , Medishetti Raghavender , Kulkarni Pushkar , Pal Manojit 
Published: January 2015

AbstractBenzimidazole functionalized quinoxalines are prepared in a multi‐component‐reaction.
ChemInform Abstract: Anionic Access to Silylated and Germylated Binuclear Heterocycles.
Authors: Boddaert Thomas , Francois Cyril , Mistico Laetitia , Querolle Olivier , Meerpoel Lieven , Angibaud Patrick , Durandetti Muriel , Maddaluno Jacques 
Published: January 2015

AbstractThe sila‐Matteson rearrangement is studied to allow access to silicon‐containing binuclear heterocycles.
ChemInform Abstract: Agelamadins A and B, Dimeric Bromopyrrole Alkaloids from a Marine Sponge Agelas sp.
Authors: Kusama Taishi , Tanaka Naonobu , Sakai Kanae , Gonoi Tohru , Fromont Jane , Kashiwada Yoshiki , Kobayashi Jun'ichi 
Published: January 2015

AbstractTitle compounds (I) show antimicrobial activity against B.
ChemInform Abstract: Entangled Structures in Polyoxometalate‐Based Coordination Polymers
Authors: He Wen‐Wen , Li Shun‐Li , Zang Hong‐Ying , Yang Guang‐Sheng , Zhang Shu‐Ran , Su Zhong‐Min , Lan Ya‐Qian 
Published: January 2015

AbstractReview: 112 refs.
Synthesis and Biological Evaluation of Ferrocenylquinoline as a Potential Antileishmanial Agent
Authors: Yousuf Md , Mukherjee Debarati , Pal Abhishek , Dey Somaditya , Mandal Supratim , Pal Chiranjib , Adhikari Susanta 
Published: January 2015

AbstractThe emergence of resistance against antileishmanial drugs in current use necessitates the search for new classes of antileishmanial compounds. Herein we report the design, synthesis, and evaluation of a novel ferrocenylquinoline for activity against Leishmania donovani. 7‐Chloro‐N‐[2‐(1H‐5‐ferrocenyl‐1,2,3‐triazol‐1‐yl)ethyl]quinolin‐4‐amine (1) was generated by coupling an iron(II) ethynylferrocene species with 4‐(2‐ethylazido)amino‐7‐chloroquinoline using click chemistry. The synthesized compound 1 was tested for its antileishmanial activity using both promastigote and amastigote stages of L. donovani. Compound 1 showed promising anti‐promastigote activity, with an IC50 value of 15.26 μM and no cytotoxicity toward host splenocytes. From the battery of tests conducted in this study, it appears that this compound induces parasite death by promoting oxidative stress and depolarizing the mitochondrial membrane potential, thereby triggering apoptosis. These results suggest that ferrocenylquinoline 1 is a suitable lead for the development of new antileishmanial drugs.
Social sensing enhanced time estimation for bus service
Authors: Liu Jin , Li Juan , Cui Xiaohui , Niu Xiaoguang , Sun Xiaoping , Zhou Jing 
Published: January 2015

SummaryThe precise prediction of bus routes or the arrival time of buses for a traveler can enhance the quality of bus service. However, many social factors influence people's preferences for taking buses. These social factors may include heavy traffic cost, traffic congestion, poor air quality and so forth. Existing prediction techniques rarely consider social sensing when predicting the bus arrival time. Accordingly, this paper proposes a social sensing enhanced service for predicting bus routes, which integrates sensing ability and social networks to understand and measure the influence between social events and vehicle velocity. We focus on the analysis of two different attributions: PT service quality attributions PEAs and road condition attributions PRCAs. Both of them synthesize the social sensing in their evaluation of bus routes. PEA represents individual preferences and PRCA represents physical factors that significantly influence vehicle velocity. Bus relevant social events were further categorized into PEA events or PRCA events. PEAs of buses were scored according to the tendency of bus conditions reflected in social events. Furthermore, an artificial neural network prediction model is established to estimate the bus travel time. Copyright © 2015 John Wiley & Sons, Ltd.
Transcriptomics of two evolutionary novelties: how to make a sperm‐transfer organ out of an anal fin and a sexually selected “sword” out of a caudal fin
Authors: Kang Ji Hyoun , Manousaki Tereza , Franchini Paolo , Kneitz Susanne , Schartl Manfred , Meyer Axel 
Published: January 2015

AbstractSwords are exaggerated male ornaments of swordtail fishes that have been of great interest to evolutionary biologists ever since Darwin described them in the Descent of Man (1871). They are a novel sexually selected trait derived from modified ventral caudal fin rays and are only found in the genus Xiphophorus. Another phylogenetically more widespread and older male trait is the gonopodium, an intromittent organ found in all poeciliid fishes, that is derived from a modified anal fin. Despite many evolutionary and behavioral studies on both traits, little is known so far about the molecular mechanisms underlying their development. By investigating transcriptomic changes (utilizing a RNA‐Seq approach) in response to testosterone treatment in the swordtail fish, Xiphophorus hellerii, we aimed to better understand the architecture of the gene regulatory networks underpinning the development of these two evolutionary novelties. Large numbers of genes with tissue‐specific expression patterns were identified. Among the “sword genes” those involved in embryonic organ development, sexual character development and coloration were highly expressed, while in the gonopodium rather more morphogenesis‐related genes were found. Interestingly, many genes and genetic pathways are shared between both developing novel traits derived from median fins: the sword and the gonopodium. Our analyses show that a larger set of gene networks was co‐opted during the development and evolution of the “older” gonopodium than in the “younger,” and morphologically less complex trait, the sword. We provide a catalog of candidate genes for future efforts to dissect the development of those sexually selected exaggerated male traits in swordtails.