bluuebunny/crossref_metadata_2025_split huggingface dataset:
Is there an editorial glass ceiling? Editorial leadership in nephrology and transplantation journals: A gender‐based cross‐sectional analysis
Authors: Scarlato Rose‐Marie , Wyburn Kate , Wyld Melanie L. 
Published: August 2024

AbstractAimEditors‐in‐Chief (EiC) play a key role as gatekeepers in academic medicine, often shaping research agendas. Women have historically been underrepresented in editorial leadership roles in academic medicine. The purpose of this study was to examine gender representation among EiC of contemporary transplantation and nephrology journals.MethodsThis cross‐sectional study evaluated gender disparities among EiC of transplantation and nephrology medical journals. The study population was drawn from journals in two subject categories (1) ‘Transplantation’ and (2) ‘Urology and Nephrology’ in the 2023 Journal Citation Reports. Binary gender classification (woman/man) was determined by the names/pronouns used to describe the EiC on the journal or institutional webpage. The primary outcome was the proportion of women EiC. Secondary outcome was the proportion of women EiC based on journal topic, location and metrics. Descriptive statistics were used. Gender differences were compared using students t‐test or Fisher's exact test.ResultsA total of 79 EiC were identified of which 16 (20%) were women and 63 (80%) were men (p < .001). Transplantation and nephrology journals had 21% and 20% women EiC, respectively. The proportion of women to men EiC was not impacted by journal category (p = .93), journal location (p = .61), journal impact factor (p = .71) or quartile (p = .59).ConclusionThere was a disparity in gender representation in EiC in nephrology and transplantation journals, with men holding 80% of all positions. These findings, among growing evidence of gender disparity, highlight a need for targeted efforts to promote gender equity in academic medicine.image
Reciprocal Evaluation of Hybrid Wheat (Triticum aestivum L.) Crosses Between German and US ‘Great Plains’ Genotypes Across Their Contrasting Target Environments
Authors: Schneider Johannes , Frels Katherine , Sakhale Sandeep , Baenziger P. Stephen , Longin C. Friedrich H. , Reif Jochen C. , Schulthess Albert W. 
Published: August 2024

ABSTRACTHybrid wheat could deliver the grain yield (GY) and stability levels to confront climate change while crossing genetically divergent pools should maximize heterosis. We crossed 22 breeding lines from Nebraska (USA) with two German cultivars to produce 44 hybrids. Hybrids, parents and 12 checks were reciprocally tested across their contrasting target environments for GY, plant height and flowering biology during 2 consecutive years at multiple locations. Trait variation within target environments had the greatest impact on performance. Therefore, mega‐environments could not be derived from target environments despite a clear clustering using weather variables. Short plants and locally optimized flowering biology were main drivers for crop performance and adaptation. Modified Rogers' distances derived from genotyping‐by‐sequencing revealed the genetic divergence between German and ‘Great Plains’ pools. However, variation on GY heterosis could not be explained by this divergence. In general, GY of hybrids was more stable across target environments than for locally adapted material, whereas GY heterosis was higher under harsh climate conditions of the Nebraska's ‘Great Plains’.
Donor Characteristics and Outcomes of Pediatric Heart Transplantation in South Korea
Authors: Kim Susan Taejung , Shin Hyewon , Yu Jeong Jin , Lee Sang Yun , Ahn Joonghyun , Song Jinyoung 
Published: August 2024

ABSTRACTBackgroundHeart transplantation is often limited by the availability of transplantable donor heart and understanding of donor aspects that would influence transplant outcomes becomes important. In this study, donor characteristics and their impact on the outcomes of pediatric heart transplantations performed in South Korea were investigated.MethodsWe reviewed the medical records of patients less than 18 years old who received heart transplantation between 2002 and 2022 in three tertiary hospitals located in South Korea.ResultsA total of 139 cases were enrolled. One‐year mortality was 10.4% and total mortality was 33.8%. Forty‐nine recipients (35.3%) showed biopsy‐proven rejections and 20 (14.4%) showed cardiac allograft vasculopathy during mean follow‐up of 6.4 ± 4.9 years. Six recipients (4.5%) showed left ventricle ejection fraction of less than 55% post‐transplantation. The mean age of the donors was 23.0 ± 15.4 years. The most common cause of death of the donors was unspecified illness (46.4%). Donors with a history of diabetes, hypertension, smoking, and alcohol consumption were 0%, 3.1%, 32.1%, and 34.4%, respectively. Mean total ischemic time was 191.6 ± 72.7 min, while total ischemic time was over 4 h in 37 patients (26.6%). There were no significant relationship between donor factors and survival. However, donor's history of drinking or cardiopulmonary resuscitation was significantly associated with acute rejection and donor's age with cardiac allograft vasculopathy.ConclusionDonor factors did not show significant impact on post‐transplant survival but some factors were predictive of post‐transplant rejection and cardiac allograft vasculopathy.
How does chronic disease influence subjective life expectancy among middle‐aged and older adults? Evidence from the China Health and Retirement Longitudinal Study (CHARLS) 2018 cross‐sectional data
Authors: Tang Shao‐Liang , Feng Yu‐Li , Gong Yue , Dong Hui‐Qiu , Qian Yu‐Xin , Chen Lei 
Published: August 2024

AbstractChronic diseases have become one of the most important factors threatening human health. Subjective life expectancy (SLE) describes an individual's expectation or subjective perception of lifespan. This article aims to explore the relationship between chronic diseases and SLE, as well as the differences among different age groups and different types of chronic diseases in this relationship.China Health and Retirement Longitudinal Study (CHARLS) is a nationwide longitudinal study that evaluates the social, economic, and health conditions of middle‐aged and older adult families and individuals aged 45 and above in China. In this study, CHARLS used probability proportional to size sampling (PPS sampling) to ensure the breadth and representativeness of the sample. This study selected cross‐sectional data from CHARLS 2018, removed missing values, and obtained a valid sample of 10,658 middle‐aged and older individuals, of whom 8564 had chronic diseases. After controlling demographic, health behavior, socioeconomic, psychological, and social security factors, an ordered logistic regression was performed to explore the relationship between chronic disease and SLE in middle‐aged and older adults.The results show that chronic diseases negatively correlate with SLE in middle‐aged and older adults. Middle‐aged and older adults with chronic diseases are 36.2% less likely to have high life expectancy than those without chronic diseases. Many different types of chronic diseases are negatively correlated with SLE. Cancer is most negatively correlated with SLE, far exceeding other chronic diseases. Chronic disease and SLE of middle‐aged and older adults have age‐heterogeneous differences. For middle‐aged people aged 45–59 and young older adults aged 60–79, there is a significant correlation between chronic diseases and SLE. However, there is no correlation between chronic diseases and subjective life expectancy in the older population aged 80 and above.The government and society should pay close attention to the prevention and treatment of chronic diseases among middle‐aged and older adults and adjust policies and measures according to the population's age structure. In addition, the government and society should pay attention to the spiritual needs of middle‐aged and older adults. The government and society should pay more attention to cancer patients. Finally, the scientific research team should also strengthen research on chronic diseases, research and development of specific drugs and vaccines, improve the cure rate of chronic diseases, promote people's health, and make people no longer afraid of diseases.
A multimodal non‐pharmacological intervention for persons with dementia in nursing homes: a multicentre randomised controlled trial
Authors: Yorozuya Kyosuke , Kubo Yuta , Asaoka Yoshihiro , Hayashi Hiroyuki , Fujita Takashi , Hanaoka Hideaki 
Published: August 2024

AbstractBackgroundPersons with dementia in nursing homes often experience cognitive decline (e.g., memory and visuospatial/construction problems), behavioural and psychological symptoms of dementia (BPSD), and impaired activities of daily living. Therefore, comprehensive interventions for this population are needed. We assessed whether a multimodal non‐pharmacological intervention improved cognitive functions, BPSD, and activities of daily living in persons with dementia in nursing homes.MethodsThis was a multicentre randomised controlled trial. Participants were 40 persons with dementia (38 women) living in four nursing homes (intervention group = 21; control group = 19). The intervention was conducted for 8 weeks, followed by an 8‐week follow‐up. Outcome measures were scores on the Japanese version of the Neurobehavioral Cognitive Status Examination Five and the ABC Dementia Scale. In the analysis, parameters were estimated using Bayesian statistics and a mixed‐effects linear regression model for the change in each outcome measure.ResultsThere were significant between‐group differences in changes in ABC Dementia Scale BPSD scores (8‐week: posteriori median = 1.66, 95% Bayesian confidence interval 0.36–3.01; 16‐week: median = 2.37, 95% Bayesian confidence interval 0.05–4.65). There was also a significant between‐group difference in changes in Neurobehavioral Cognitive Status Examination Five constructional ability scores (16‐week: median = 0.93, 95% Bayesian confidence interval 0.35–1.50).ConclusionThis intervention may have a maintenance and improvement effect on BPSD in persons with dementia in nursing homes, and a sustained effect on constructional ability post‐intervention. The intervention may be useful and easy to apply in practice.
The effect of performance contingent reward prospects flexibly adapts to more versus less specific task goals
Authors: Liegel Nathalie , Schneider Daniel , Wascher Edmund , Klatt Laura‐Isabelle , Arnau Stefan 
Published: August 2024

AbstractIn some situations, for example, when we expect to gain a reward in case of good performance, goal‐driven top‐down attention is particularly strong. Little is known about the task specificity of such increases of top‐down attention due to environmental factors. To understand to what extent performance‐contingent reward prospects can result in specific and unspecific changes in cognitive processing, we here investigate reward effects under different levels of task specification. Thirty‐two participants performed a visual or an auditory discrimination task cued by two consecutive visual stimuli: First, a reward cue indicated if good performance was rewarded. Second, a task cue announced either which of the two tasks would follow (precise cue) or that both tasks would follow equally likely (imprecise cue). Reward and task cue preciseness both significantly improved performance. Moreover, the response time difference between precisely and imprecisely cued trials was significantly stronger in rewarded than in unrewarded trials. These effects were reflected in event‐related potential (ERP) slow wave amplitudes: Reward and preciseness both significantly enhanced the contingent negative variation (CNV) prior to the task stimulus. In an early CNV time interval, both factors also showed an interaction. A negative slow wave prior to the task cue was also significantly enhanced for rewarded trials. This effect correlated with the reward difference in response times. These results indicate that reward prospects trigger task‐specific changes in preparatory top‐down attention which can flexibly adapt over time and across different task requirements. This highlights that a reward‐induced increase of cognitive control can occur on different specificity levels.
Role of pediatric dentist in West syndrome rehabilitation: A case report
Authors: Mehrotra Deepshikha , Nayak Prajna P. , Naik Shilpa Shetty , Krishna Nidhish 
Published: August 2024

AbstractAimWest syndrome is characterized by a triad of infantile spasms, arrested psychomotor development, and pronounced paroxysmal electroencephalogram (EEG) abnormalities, notably hypsarrhythmia. This case report aims to discuss the various considerations and strategies for the dental management of a child with West syndrome.Method and ResultThis report focuses on a case of a 5‐year‐old girl diagnosed with West Syndrome who presented for her first dental visit with complaints of pain and swelling in the right posterior tooth region for the past three weeks. Due to frequent seizure episodes, neuropsychomotor delay, and multiple dental treatment needs, comprehensive full‐mouth rehabilitation was performed under general anesthesia.ConclusionAwareness of syndromes like West syndrome equips dentists to better manage children with complex conditions. Additionally, parental counselling and early preventive measures can significantly reduce the added burden of dental diseases in these patients.
In vitro efficacy of lavender oil, otological gel and gentamicin to eradicate biofilm produced by Pseudomonas aeruginosa
Authors: Mourão Ana , Serrano Isa , Cunha Eva , Tavares Luís , Lourenço Ana , Oliveira Manuela 
Published: August 2024

AbstractBackgroundOtitis externa (OE) is one of the most frequently diagnosed dermatological diseases in dogs, having a multifactorial aetiology. Among the bacterial agents associated with canine OE, Pseudomonas aeruginosa is of special concern owing to its frequent multidrug resistance profile and ability to form biofilms related to the infection's chronicity and recurrence.ObjectivesThe main objective of this study was to evaluate and compare the antibiofilm activity of two innovative antimicrobials—an otological gel containing a synthetic antimicrobial peptide and Lavandula angustifolia essential oil—with gentamicin (a conventional antibiotic) using biofilm‐producing P. aeruginosa isolates obtained from dogs with OE.Materials and MethodsThe biofilm eradication capacity of gentamicin, otological gel and lavender oil was determined against a collection of 12 P. aeruginosa biofilm‐producers among 35 clinical isolates obtained from the ear canals of dogs with OE. Also, the antimicrobial activity of the otological gel against P. aeruginosa biofilms was assessed in an in vitro model of dog cerumen.ResultsLavender oil showed the best effectiveness after 30 min of contact, eradicating 58.3% (seven of 12) of the isolates, and gentamicin showed full eradication (12 of 12) after 24 h. The otological gel acted more slowly than the lavender oil; yet at 24 h, the antibiofilm capacity of both compounds was similar, with no significant difference between them. It also was found that triglycerides from synthetic cerumen earwax had antipseudomonal activity and, when combined with the otological gel, led to the full eradication of P. aeruginosa.Conclusions and Clinical RelevanceThe results of this in vitro study indicate that lavender oil and the otological gel may be effective topical treatments for canine OE promoted by P. aeruginosa biofilm‐producers, as alternatives to gentamicin.
Identification of cross‐reactive allergens between the Dermatophagoides farinae house dust mite and the Toxocara canis nematode in dogs with suspected allergies
Authors: Olivry Thierry , Mas‐Fontao Ana , Jacquenet Sandrine , Aumayr Martina , Tsukui Toshihiro , Gomord Véronique , Faye Loïc , Favrot Claude 
Published: August 2024

AbstractBackgroundImmunoglobulin (Ig)E cross‐reactivity has been shown between Dermatophagoides farinae (Df; house dust mite) and the nematode Toxocara canis (Tc), yet its allergen basis is unknown.ObjectivesTo identify the Df allergens IgE‐cross‐reactive with those of Tc.AnimalsArchived sera from 73 dogs with suspected allergy sensitised to Df.Materials and MethodsWe performed a combination of Pet Allergy Xplorer (PAX) and enzyme‐linked immunosorbent assay (ELISA) inhibitions with excretory–secretory and somatic (i.e. nematode body) extracts of Tc or recombinant Tc tropomyosin on coats of Df, Der f 15 and Zen‐1 (ELISA) or PAX allergens.ResultsThe ELISA and PAX inhibitions established that there is mutual yet variable cross‐reactivity between the Tc excretory–secretory extract, purified Der f 15 and purified Zen‐1. This cross‐reactivity is likely to involve cross‐reactive glycans, as there is no inhibition between the Tc excretory–secretory extract and recombinant Der f 15 without its predicted natural O‐glycans. We also confirmed a heterogeneous cross‐reactivity between the somatic Tc extract and Der p 11 (paramyosin), as well as between the recombinant Toxo c 3 and Der p 10 tropomyosins. The cross‐reactivity among tropomyosins and paramyosins is likely to involve peptidic epitopes, as these recombinant allergens are not glycosylated.Conclusions and Clinical RelevanceIn dogs with suspected allergies, the cross‐reactivity between Tc and Df for dogs is complex and heterogeneous. Some of the cross‐reactive IgE recognises shared glycans on Der f 15 and Zen‐1, while some targets peptidic epitopes on shared paramyosins and tropomyosins. We do not exclude that additional cross‐reactive allergens between Df and Tc also might exist.
High-Volume Production of Repeatable High Enhancement SERS Substrates Using Solid-State Superionic Stamping
Authors: Sultana Papia , Qian Boqiang , Son ChangHee , Kim Seho , Mensing Glennys , Ferreira Placid 
Published: August 2024

Abstract
Surface-enhanced Raman spectroscopy (SERS) is emerging as a powerful tool for detecting and identifying chemical and biological substances because of its high sensitivity, specificity, speed, and label-free detection. For SERS substrates to be effective in sensing applications, they must exhibit reproducible and robust high signal enhancement and cost-effective scalability. This article introduces a highly sensitive, large-area silver SERS substrate patterned with a uniform array of 3D retroreflecting inverted pyramids and develops a manufacturing pathway for it, using a novel and facile electrochemical imprinting process called solid-state superionic stamping (S4). Substrates, approximately 4 mm2 in area, are produced and tested with 1,2-bis(4-pyridyl) ethylene (BPE). Uniformly high and reproducible spatially averaged enhancement factor (EF), typically around a value of 2 × 107 with a relative standard deviation of 6.7% and a high batch-to-batch repeatability with a relative standard deviation of 10.5% between batches were observed. Passivating a substrate's surface with atomically thin layers of alumina, deposited using atomic layer deposition (ALD) was effective in maintaining the EF constant over a 60-day period, albeit with a trade-off between its EF and its lifespan. S4 has the potential to make substrates with EF consistently greater than 107 available at a cost of $1 to $2 per substrate, allowing SERS to be adopted across a wide spectrum of high-volume applications, including security, food safety, medical diagnostics, and chem-bio analysis.
Debonding Fiber Damage Mechanism Modeling for Machining Damage Inhibition During Rotary Ultrasonic Face Grinding SiO2f/SiO2
Authors: Yao Longxu , Liu Zhanqiang , Song Qinghua , Wang Bing , Cai Yukui , Luan Qiang , Wang Hongxin 
Published: August 2024

Abstract
The debonding fiber defects on the grinding surface of SiO2f/SiO2 ceramic matrix composites deteriorate the service performance of related components. The low-damage process window is the key information to suppress machining damage by controlling grinding parameters. A mechanism model for debonding fiber damage on SiO2f/SiO2 surface was first proposed in this paper by the large deformation analysis for SiO2 fibers during rotary ultrasonic face grinding (RUFG). The established mechanism model built a bridge between grinding parameters and damage inhibition by integrating the ultrasonic stress effect, grinding force calculation, and critical fracture curvature cutting-off criterion of SiO2 fibers. The modeling mechanism for fiber deformation and fracture in grinding was validated by in situ observation of single abrasive grit scratching experiments. Besides, the low debonding damage process window predicted by the model was verified by experimental results and could be adopted to suppress the debonding fiber damage in grinding. The affected mechanism of fiber orientation, ultrasonic amplitude, and fiber-matrix interface strength on the low debonding damage process window was analyzed based on the theoretical and experimental results. The damage inhibition effect of the RUFG process was limited by the low fiber-matrix interface strength and axial cutter-relieving movement component. The ultrasonic-assisted vibration exerted its auxiliary effects through the ultrasonic stress effect and force reduction effect. The prerequisite for exerting the damage inhibition effect of RUFG was that the fiber-matrix interface strength was sufficient to resist the negative influence of the ultrasonic stress effect.
A Surrogate Model to Predict Stress Intensity Factor of Tubular Joint Based on Bayesian Optimization Gaussian Process Regression
Authors: Leng Jiancheng , Zhang Jiajia , Zhang Jinbo , Chen Zitong 
Published: August 2024

Abstract
The tubular joints located in the splash zone of the jacket platform are prone to damage or even crack due to long-term loads such as wind, wave, and current. If the crack development is not monitored and tracked, serious consequences will be caused. Aiming at the problem of long calculation time and low efficiency of stress intensity factor (SIF) in fracture mechanics, a method based on Gaussian process regression is proposed to construct the SIF surrogate model of tubular joints. By conducting mechanical simulation analysis on the tubular joint of the jacket platform under extreme storm load conditions, the dangerous position of the tubular joint is determined, cracks are introduced, and crack propagation simulation is carried out to obtain training data for the surrogate model. The Gaussian process regression surrogate model is established based on the composite kernel function, and the Bayesian optimization is introduced to optimize the hyper-parameters of the kernel function to determine the optimal surrogate model and verify the accuracy. The results show that the maximum mean relative error (MRE) of the SIF obtained by the proposed method is 4.94%, and the average value of MRE is only 0.41%. At the same time, the calculation time is reduced from about 4 h to 2.9 s, providing a method reference for real-time prediction of crack growth of jacket platform under the background of digital twin.