bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical significance of atypical glandular cells on cytology: 10 years’ experience of a colposcopic referral center
Authors: Monti Ermelinda , Di Loreto Eugenia , Libutti Giada , Alberico Daniela , Barbara Giussy , Boero Veronica , Cetera Giulia Emily , Pasquali Coluzzi Maria , Cipriani Sonia , Parazzini Fabio 
Published: August 2024

Introduction
‘Atypical glandular cells’ (AGC) is an uncommon cytological result of cervical Pap smears which includes a wide of histopathological diagnoses, from benign to premalignant and malignant cervical disorders, endometrial cancer and, occasionally, other genital malignancies. This study aims to provide a comprehensive overview of AGC, assessing risk factors and clinical and histological features in affected patients.

Materials and methods
A retrospective analysis was conducted on a cohort of 239 women diagnosed with AGC between 2012 and 2022 at the ‘Regional Referral Center for Prevention, Diagnosis and Treatment of HPV-related Genital Disorders’, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy. Following AGC detection, patients underwent colposcopy with endocervical sampling and endometrial assessment via pelvic ultrasound. Selective cases also received endometrial biopsies.

Results
Among a total of 190 women who underwent both colposcopy and endometrial assessment, 116 (61%) had negative clinical and histopathological findings. The remainder displayed various abnormalities: 36 women (18.9%) were found to have endometrial or cervical polyps, 23 (12.1%) were diagnosed with preinvasive cervical neoplasia, and 21 (10.9%) with invasive cervical or endometrial disease. Menopause, multiparity, and older age were all significantly associated with endometrial cancer, but none of the abovementioned variables were significantly associated with cervical neoplasia.

Conclusion
Our data confirm that AGC may reveal the presence of a wide range of histopathological conditions. Patients diagnosed with AGC should undergo a careful evaluation including both colposcopy with endocervical sampling and an endometrial assessment.
Emerging trends in early-onset gastric cancer
Authors: Wang Xinlin , Gao Xianchun , Yu Jun , Zhang Xiaotian , Nie Yongzhan 
Published: August 2024

Abstract
The incidence of early-onset gastric cancer (EOGC) is consistently increasing, and its etiology is notably complex. This increase may be attributed to distinctive factors that differ from those associated with late-onset gastric cancer (LOGC), including genetic predispositions, dietary factors, gastric microbiota dysbiosis, and screening of high-risk cases. These factors collectively contribute to the onset of cancer. EOGC significantly differs from LOGC in terms of clinicopathological and molecular characteristics. Moreover, multiple differences in prognosis and clinical management also exist. This study aimed to systematically review the latest research advancements in the epidemiological characteristics, etiological factors, clinicopathological and molecular features, prognosis, and treatment modalities of EOGC.
A Review of Linear Lichen Planus Case Reports
Authors: Rousseau Morgan A. , Nelson Emelie E. , Rashid Rashid M. 
Published: August 2024

Abstract:
Lichen linear planus is a rare variant of lichen planus that appears as pruritic, polygonal, purple papules in a blaschkoid distribution. This review critically assesses all reported cases of linear lichen planus (LLP) for proposed etiology, clinical and histologic traits, treatment options, and recurrence. A PubMed search from inception through March 2023, followed by article screening and full-text review, identified 51 unique cases of LLP. Data from each case including the sex of the patient, anatomic distribution of lesions, biopsy results, proposed etiology, treatment, and recurrence were recorded. LLP did not show a significant gender or age predilection, most frequently presented unilaterally with pruritus, and involved numerous anatomic regions. Various triggers including metal implants, vaccinations, infections, malignancy, and pregnancy were identified. The most common histopathologic descriptions included band-like lymphocytic or lichenoid infiltrate, basal liquefactive, vacuolar degeneration, hypergranulosis, hyperkeratosis, civatte or colloid bodies, melanin incontinence, and orthokeratosis. Treatment options, duration of treatment, and recurrence rate of LLP lesions were variable. Although LLP is rare, dermatologists should be aware of this presentation and appropriate diagnostic and treatment options because swift diagnosis can reduce patient morbidity.
Functional, Cosmetic, and Psychological Outcomes after Rhinoplasty
Authors: Omer Goran , Girolamo Stefano , Hamatofiq Binaiy , Tofiq Sozyar , Mohammed Mawa Aziz , Abdulkarim Diya , Mohammed Shnya , Gubari Mohammed , Habibullah Imad , Mustafa Ayman , Fatah Mariwan , Ahmed Sarwat , Kakamad Fahmi 
Published: August 2024

Background:
Rhinoplasty is conducted to address both cosmetic and functional objectives. It is not merely a cosmetic procedure, as it frequently aims to improve function by enhancing nasal breathing and removing congenital or acquired obstructions. The current study aims to determine the functional, cosmetic, and psychological outcomes of rhinoplasties.

Methods:
This is a descriptive cross-sectional study. The data were collected using an interview and an online Google form. A chi-square test was used to determine the relationship between qualitative variables and quantitative variables using frequency, percentage, and mean for quantitative variables. Each variable’s P value is used to detect statistical significance. The significance level was set at a P value of less than 0.05.

Results:
Of the 234 patients enrolled in this study, 69.2% were women, whereas 30.8% were men, with a mean age of 22.86 ± 4.546 years. In terms of satisfaction, functional satisfaction accounted for about 59% of all satisfaction, cosmetic satisfaction was 63.2%, and psychological satisfaction was 70.9%. The primary reason for surgery was cosmetic (45%).

Conclusion:
The majority of enrolled participants were satisfied with their functional outcomes, whereas their satisfaction with psychological and cosmetic outcomes was moderate.
Associations of Neighborhood Environments and Socioeconomic Status With Subclinical Atherosclerosis
Authors: Hajj Jihane , Schneider Andrea L. C. , Jacoby Douglas , Schreiber James , Nolfi David , Turk Melanie T. 
Published: August 2024

Background
A limited understanding exists on the associations of neighborhood environment with subclinical atherosclerosis and its progression.

Purpose
The purpose of this integrative review was to explore associations of neighborhood environments and socioeconomic status (SES) with subclinical atherosclerosis and its long-term progression.

Results
Three themes were identified: environmental exposure affects the natural history of atherosclerosis, neighborhood characteristics are associated with subclinical atherosclerosis, and individual SES is associated with development and progression of subclinical atherosclerosis more so than neighborhood SES. Some variations in results were noted based on the vascular site examined.

Clinical Implications
Disadvantaged neighborhoods and low SES are associated with greater subclinical atherosclerosis. Inconsistencies in a few studies seemed to be related to lack of coronary artery progression among the relatively young adults. This suggests further examination is needed of the contextual associations of neighborhood and SES with markers of generalized atherosclerosis, such as carotid intima-media thickness.
Association of pitavastatin use with bone markers and bone mineral density in postmenopausal women
Authors: Hyun Jihye , Sohn Minji , Oh Hyeran , Lim Soo 
Published: August 2024

AbstractBACKGROUNDThe study aimed to evaluate the effects of pitavastatin therapy on biochemical markers of bone turnover and bone mineral density (BMD) in postmenopausal women with osteopenia or osteoporosis and hypercholesterolemia.METHODS AND RESULTSThis prospective observational study recruited 70 postmenopausal Korean women who were administered pitavastatin. Changes in BMD at the femoral neck (FN), total hip (TH), and lumbar spines (LS), as well as laboratory values related to bone turnover markers and lipid profiles, including lipoprotein subfractions, were assessed over 12 months. BMD was further observed during regular clinic visits up to 4 years. A total of 67 patients completed 12 months of pitavastatin therapy. There were no significant changes in BMD (–0.001 ± 0.026 at FN, –0.005 ± 0.032 at TH, and 0.002 ± 0.037 at LS; all Ps > 0.05). Bone markers did not change except for procollagen type 1 N-propeptide (P1NP), which slightly decreased (–4.0 ± 10.3,P< 0.05). Low-density lipoprotein (LDL) cholesterol levels decreased by 36% to 39% from baseline, and the LDL subfraction score decreased from 2.85 ± 1.79 to 1.80 ± 0.63 (P< 0.001). During the extended observation period, BMD at FN and TH decreased by 0.85% and 1.69% per year, respectively, while BMD at the LS was preserved.CONCLUSIONSIn postmenopausal women with osteopenia or osteoporosis requiring lipid-lowering therapy, one year of pitavastatin maintained BMD and effectively controlled cholesterol levels. BMD changes during statin therapy were more favorable than the natural decline. These findings suggest pitavastatin can be safely used in menopausal women without compromising bone health.
Chimeras of Kinesin-6 and Kinesin-14 reveal head-neck-tail domain functions and dysfunctions that lead to aneuploidy in fission yeast
Authors: Sasmal Priyanka , Miyazaki Makito , Carlier-Grynkorn Frédérique , Tran Phong T. 
Published: August 2024

AbstractKinesin motors play diverse roles in cells, including spindle assembly and chromosome segregation. Each kinesin has three general domains – the motor head, neck, and tail. As microtubule (MT) motors, kinesins have directionality, walking toward the plus- or minus-end of a MT. Plus-end kinesins have their motor head at the N-terminus, while minus-end kinesins have their motor head at the C-terminus. Interestingly,in vitrodata indicate that the motor head does not dictate directionality. Here, we seek to understand the cellular function of each kinesin domain. We systematically created chimeras of fission yeast kinesin-6 Klp9 (a plus-end kinesin localized at the spindle midzone to slide the MTs and elongate the spindle) and kinesin-14 Pkl1 (a minus-end kinesin localized at the spindle poles to focus MTs). Ourin vivodata reveal that the tail dictates cellular localization, and in some cases directionality of the motor head; the motor head produces binding and sliding forces affecting spindle function; and the neck modulates the forces of the motor head. Specifically, Pkl1-head, when put on Klp9-neck-tail, walks toward the spindle midzone and slides MTs faster than the wild-type Klp9. This results in spindle breakage and aneuploidy. In contrast, Klp9-head, when put on Pkl1-neck-tail, localizes to the spindle poles, but failed to properly focus MTs, leading to abnormal MT protrusions. This results in asymmetric displacement of the chromosomes and aneuploidy. Our studies reveal domain-dependent control of motor localization, direction, and force production, whose dysfunctions lead to different modes of aneuploidy.
Decoding the source of value: evidence from listed firms in India
Authors: Mishra Sanjay Kumar 
Published: August 2024

PurposeThe objective of the study is to investigate the factors that differentiate long-term shareholder value (LTSV) creating firms from LTSV destroying firms.Design/methodology/approachThrough the review of literature, the hypothesis for the study is developed. To test the hypothesis, the study collects data from S&P BSE 500 companies listed in Bombay Stock Exchange (BSE). Based on the average overall return to shareholders for the period from year 1991 to 2019, the study identifies top 25 LTSV creating and LTSV destroying firms. The top 50 firms form the basis of this study. The study uses descriptive statistics and independent sample t-test to test the hypothesis of the study.FindingsAmong the variables investigated such as capital management policy and effective capital management practices, business and financial strategy, intellectual capital strategy, relational capital strategy and human capital strategy, the study found effective capital management and governance as a long-term source of value for shareholders.Research limitations/implicationsThe study highlights the importance of inclusion of value-relevant information in the annual report of the company. The study also supports the proposition that discretionary disclosure of intangible assets is relevant for the market to enable market participants to reasonably comprehend the fair value of the firm.Practical implicationsAdoption of a reporting framework that ensures the availability of all value-relevant information including off-balance-sheet resources is in the interest of the investors and policymakers alike.Originality/valueThis is a first such study exploring the value-relevant information and the source of long-term value for listed firms.
Consumer education strategies for overcoming prefabricated housing challenges in China: a systematic review
Authors: Yao Yicheng , Gurmu Argaw 
Published: August 2024

PurposePrefabricated housing is a construction method that largely reduces construction waste and promotes sustainable development. However, the adoption of this method of construction is inhibited by the lack of demand by consumers. The purpose of this research is to explore consumer education strategies aimed at overcoming prefabricated housing challenges in China.Design/methodology/approachThe study conducted a systematic literature review following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. A comprehensive search was conducted using databases such as Scopus and Web of Science, without any restriction on publication date. A total of 33 relevant articles were retrieved and analyzed using the content analysis method. The findings were then summarized and presented using the tabulation technique.FindingsThis study identified several barriers to prefabricated housing, including negative perception, limited public understanding, risk-averse culture and lack of green value. To foster market demand, relevant authorities should consider implementing effective educational mechanisms, such as comparative advertising, social media marketing, school programs and critical adult education programs. These strategies can effectively overcome the existing negative perception, alleviate concerns and create a positive environment for the growth of prefabricated housing in China.Originality/valueThis research provides practical and theoretical implications by identifying key challenges to prefabricated housing and suggesting targeted educational strategies to address them. It offers valuable guidance for policymakers, industry stakeholders and researchers, contributing to the advancement of sustainable housing practices.
Slowing down in the final lap: investigating the effect of CEO career horizon on green innovation in China
Authors: Yin Nianwei , Wang Ruzhou , Jia Liangding 
Published: August 2024

Purpose
Drawing on upper echelons theory, the authors study how the career horizon of a CEO promotes green innovation through the incentive mechanism. Meanwhile, from the perspective of speed and amount of value realization, the authors also identify two sets of shift parameters that reduce or increase incentive gap between short-career-horizon CEOs and long-career-horizon CEOs. Specifically considering the digital trend in China and the heterogeneity of firms and industries, this study aims to examine the moderating effects of firm digitalization, industrial digital transformation, slack resources and polluting firms.

Design/methodology/approach
In the context of China’s transitional economy, this study uses all A-share listed companies in China from 2007 to 2021, resulting in a total of 4,286 companies with 29,310 company-year observations.

Findings
The results support the hypothesis that CEO career horizon significantly facilitates green innovation at the firm level. The positive effect is attenuated by both firm digitalization and industrial digital transformation, but is amplified by slack resources and by the polluting firms. After a series of robustness tests, the research conclusions remain valid.

Originality/value
To extend the upper echelons perspective of existing research into CEO−green innovation, the authors make important contributions in four ways. First, this study contributes to green innovation literature by adding an unexplored yet increasingly important managerial determinant. Second, it advances research on the role of the CEO in green innovation by revealing a new theoretical mechanism. Third, it deepens the understanding of CEO career horizon by exploring its influence on innovations in the context of corporate social responsibility (CSR). Fourth, it identifies boundary conditions that motivate CEOs in distinguishable ways, to provide a nuanced understanding of the relationship between CEO career horizon and green innovation.
Evaluation of market transformation efficiency of urban investment and development companies based on the three-stage DEA model
Authors: Tang Wenbin , Chen Xia , Zhang Xue , Peng Zhihong 
Published: August 2024

Purpose
This study aims to explain the market-oriented transformation dilemma of Chinese urban investment and development companies (UIDCs; also known as local government investment and financing companies) and objectively evaluate their transformation efficiency from both static and dynamic perspectives. The results of the research provide methodological bases for improving the transformation efficiency of UIDCs, thus pointing out the direction for the rational planning of their transformation path.

Design/methodology/approach
This study takes Chinese UIDCs in market transformation during 2015–2019 as the research object and uses principal component analysis to screen the index system for measuring the efficiency of market transformation. It then uses a three-stage data envelopment analysis model and the Malmquist productivity index to evaluate the market transformation efficiency of these companies during 2015–2019 and comprehensively analyzes the influence of external environmental factors on the market transformation of Chinese UIDCs.

Findings
Research results show that the transformation efficiency of Chinese UIDCs is low and slow overall and that large spatial and temporal differences exist. The transformation efficiency of UIDCs located in eastern China is higher than that of UIDCs in central and western China. The higher the external environmental factors of regional GDP, local debt service pressure and credit rating, the more likely they are to cause input redundancy in the transformation process of Chinese UIDCs, which is not conducive to their market-oriented transformation. In addition, the higher the urbanization rate, the more effective it is to improve the efficiency of market-oriented transformation of UIDCs. If the influence of environmental factors is stripped away, both the overall efficiency value and pure technical efficiency value of market-oriented transformation of Chinese UIDCs will increase while the scale efficiency value becomes smaller.

Originality/value
This research measures the transformation efficiency of Chinese UIDCs and comprehensively analyzes the influence of external environmental factors on their market-oriented transformation. The goal is to enrich the study of the market-oriented transformation efficiency evaluation index system of Chinese UIDCs at the theoretical level and provide important reference values for improving the efficiency of market-oriented transformation of Chinese UIDCs at the practical level.
English, German and Indonesian nominalizations: a contrastive study and their application in teaching English to Indonesian learners of German
Authors: Muhammad Anwar , Yusri Yusri , Mantasiah R. , Jufri Jufri 
Published: August 2024

PurposeThis study aimed to investigate the process of nominalization in English, German, and Indonesian, utilizing a contrastive analysis approach, and to apply the findings to teaching English to Indonesian learners of German.Design/methodology/approachThis mixed-method study used an exploratory sequential design. The qualitative method used contrastive analysis to focus on the nominalization process in English, Indonesian, and German, and the quantitative method assessed student responses related to the developed English teaching material.FindingsThe study found similarities and differences in the nominalization process between the languages, with nominalization occurring by adding various affixations. Most students considered the learning materials developed based on the findings of contrastive analysis to help understand the nominalization process in English.Practical implicationsThe study’s findings hold significant implications for the global application of foreign language teaching, particularly in English as the first foreign language (FL1) or as the second foreign language (FL2). The research suggests that an effective method of teaching English grammar involves providing examples equivalent to those used in the learner’s first language or other languages. These results may contribute to developing pedagogical practices and enhancing language learners' proficiency in FL1 and FL2 contexts.Originality/valueThis study contributes to the existing literature by comparing the nominalization process in German, Indonesian, and English and explaining how the results of contrastive analysis can be applied in teaching English to Indonesian students majoring in German.
High-strength geopolymer based engineered cementitious composites (ECC) for sustainable and resilient construction
Authors: Kanagaraj Balamurali , Anand N. , Thomas Mathew , Siew Choo Chin 
Published: August 2024

Purpose
The development of high-strength engineered cementitious composite (ECC) gains a significant leap in structural engineering. Engineers have been looking for new formulations that combine outstanding compressive strength with increased flexural resistance. This research focuses on the main characteristics, techniques and prospective applications of high-strength ECC. The proposed work explores the composition of such concrete, emphasizing the use of novel additives, fiber reinforcements and optimal particle packing to produce excellent mechanical characteristics and demonstrating how high-strength ECC contributes to incorporate sustainability by potentially lowering the need for supplemental reinforcing and resulting in a lower environmental effect.

Design/methodology/approach
This research involves on studying the composition of high-strength ECC and geopolymer-based ECC, the use of novel additives, fiber reinforcements and optimal particle packing. It examines the capacity of high-strength ECC to sustain high loads with an allowable deformation without any catastrophic collapse. It discusses the sustainability aspects of high-strength ECC and its potential alternative as geopolymer-based ECC.

Findings
High-strength ECC offers an excellent compressive strength while also providing increased flexural capacity. Employment of copper slag (CS) as a filler material for the production of ECC results in 28.92% lower cost, when compared to the mix developed using conventional river sand. Whereas in the case of geopolymer-based ECC, the cost of production was found to be 31.92% lower than that of the conventional.

Originality/value
High-strength ECC is developed using conventional river sand and industrial by-product, CS as a filler material. The combination of achieving higher compressive strength with an increased use of industrial by-products leads to the development of sustainable high strength ECC. The potential use of high-strength ECC reduces the need for supplementary reinforcing and increases the structural lifetime, resulting in a lower environmental impact.