bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hip and Glenohumeral Rotational Range of Motion in Healthy Professional Baseball Pitchers and Position Players
Authors: Sauers Eric L. , Huxel Bliven Kellie C. , Johnson Michael P. , Falsone Susan , Walters Sheri 
Published: November 2013

Background: Research suggests that limitations in the hip motion of baseball players may lead to altered motion at the glenohumeral joint to maintain throwing velocity, thereby predisposing the upper extremity to injury. Purpose: To measure and evaluate the correlation between hip and shoulder rotational range of motion (ROM) in healthy professional baseball players. Study Design: Descriptive laboratory study. Methods: Ninety-nine professional baseball players (50 pitchers and 49 position players; mean age ± standard deviation [SD], 22 ± 2.8 years; mean height ± SD, 187 ± 5.4 cm; mean weight ± SD, 81.6 ± 7.7 kg) with no history of hip or shoulder injury were tested. Dominant and nondominant hip and glenohumeral joints were measured for the following passive ROM variables: (1) hip internal rotation (IR), (2) hip external rotation (ER), (3) total hip rotational ROM (IR + ER), (4) isolated glenohumeral IR, (5) isolated glenohumeral ER, and (6) total glenohumeral rotational ROM (IR + ER). Results: Statistically, hip ER and total hip rotational ROM were greater in position players than in pitchers and less in the lead leg compared with the stance leg hip with groups combined; however, differences are not clinically meaningful. Pitchers had more glenohumeral rotational ROM than did position players. For all players, glenohumeral motion had less IR and greater ER in the throwing arm than the nonthrowing arm, but total glenohumeral rotational ROM was equivalent between sides. The correlations between hip and glenohumeral ROM were little, if any, and ranged from r = −0.19 to 0.11 ( P = .006-.94) for all players and r = −0.29 to 0.23 ( P = .04-.97) for pitchers only. Conclusion: These data suggest no clinically meaningful differences in hip ROM between pitchers and position players and between lead leg and stance legs of all players. There is little or no relationship between hip and glenohumeral ROM in healthy professional baseball players. Clinical Relevance: The study findings add to the growing body of evidence that suggests an absence of chronic hip ROM adaptations. It is therefore suggested that in the hip, unlike the glenohumeral joint, symmetry in ROM between player positions and dominant and nondominant sides should be expected in healthy professional baseball pitchers and position players.
Arthroscopic Meniscus Allograft Transplantation in Male Professional Soccer Players
Authors: Marcacci Maurilio , Marcheggiani Muccioli Giulio Maria , Grassi Alberto , Ricci Margherita , Tsapralis Kyriakos , Nanni Gianni , Bonanzinga Tommaso , Zaffagnini Stefano 
Published: November 2013

Background: Meniscus allograft transplantation (MAT) is an option for symptomatic patients who have undergone subtotal meniscectomy and can potentially result in pain relief and increased function. Hypothesis: Professional soccer players would benefit from arthroscopic MAT in terms of pain, knee function, and return to play at 36-month follow-up. Study Design: Case series; Level of evidence, 4. Methods: Twelve male patients who had undergone MAT (6 medial, 6 lateral) were prospectively evaluated at 12- and 36-month follow-up. The mean age at the time of surgery was 24.5 ± 3.6 years (range, 19-29 years), and the mean time from meniscectomy to surgery was 37 ± 31 months (range, 2-82 months). The transplantation was performed in patients who had undergone subtotal meniscectomy using an arthroscopic bone plug–free technique with a single tibial tunnel plus “all-inside” meniscus sutures. The anterior horn of the transplanted meniscus was sutured to the capsule and to the remnant of the anterior horn of the native meniscus. Seven patients (58%) underwent concurrent procedures. All patients were evaluated at follow-up by the Tegner, Lysholm, International Knee Documentation Committee (IKDC) subjective, IKDC objective, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and visual analog scale (VAS) for pain scores. Information regarding rehabilitation, return to play, and return to official competition was recorded. Results: Eleven of the 12 patients (92%) returned to play soccer. At 36-month follow-up, 9 patients (75%) were still playing as professionals (Tegner score of 10), whereas 2 patients (17%) were playing as semiprofessionals (Tegner score of 9). The mean time from surgery to the end of rehabilitation was 7.5 ± 2 months, whereas the mean time to official competition was 10.5 ± 2.6 months. Patients demonstrated significant improvements on the median Tegner score from 8 (interquartile range, 3-10) to 10 (interquartile range, 9-10) ( P = .0391); the mean Lysholm score from 67 ± 14 to 92 ± 10 ( P = .0021); the mean IKDC subjective score from 61.8 ± 16.3 to 85.3 ± 9.8 ( P = .0026); the mean IKDC objective score from 1 A, 8 B, 1 C, and 2 D to 7 A and 5 B ( P = .0077); the mean WOMAC score from 77.1 ± 15.9 to 92.2 ± 9.1 ( P = .0242); and the mean VAS score from 61 ± 16 to 29 ± 32 ( P = .0029) at 12-month follow-up. There were no significant improvements in these outcomes at 36-month follow-up. One patient developed a knee infection after MAT plus anterior cruciate ligament allograft reconstruction. This complication was successfully treated, but the patient stopped playing soccer (Tegner score of 3 at 36-month follow-up), and this was considered a failure (8%). Conclusion: Arthroscopic MAT in professional soccer players allowed a return to play at the same level (Tegner score of 10) in 75% of the cases at 36-month follow-up.
Meniscus Allograft Transplantation
Authors: Yoon Kyoung Ho , Lee Sang Hak , Park Soo Yeon , Kim Hwan Jin , Chung Kee Yun 
Published: November 2013

Background: Because of the anatomic and biomechanical differences between the lateral and medial menisci, it is believed that the indications, combined injuries, techniques, and outcomes of the 2 meniscus allograft transplantation (MAT) procedures may be different. Hypothesis: Medial meniscus transplantation (medial group) usually combines concomitant surgeries, such as anterior cruciate ligament (ACL) reconstruction, so the medial group will have worse clinical results than the lateral group (lateral meniscus transplantation). Study Design: Cohort study; Level of evidence, 3. Methods: A retrospective study was conducted on 91 patients who underwent MAT (lateral group, n = 56; medial group, n = 35). There were 33 patients with an absence of a concurrent injury (isolated group) and 58 patients with the presence of a concurrent injury (combined group). The mean follow-up was 40 months (range, 24-125 months). Clinical outcomes for range of motion (ROM), visual analog scale (VAS) for pain score, International Knee Documentation Committee (IKDC) subjective score, Lysholm score, and Tegner activity score were evaluated, and an objective evaluation was performed using magnetic resonance imaging (MRI) and second-look arthroscopic surgery. Results: At final follow-up, the mean results for ROM, VAS score, IKDC subjective score, Lysholm score, Tegner activity score, and patient subjective satisfaction were not statistically different between the lateral and medial groups ( P > .05). The VAS and Lysholm scores of the isolated group were significantly better than those of the combined group. Follow-up MRI was performed on 35 patients (24 in the lateral group and 11 in the medial group). Mean graft extrusion was 1.7 mm in the lateral group and 2.6 mm in the medial group ( P = .075). The relative percentage of extrusion was 19.4% in the lateral group and 32.0% in the medial group ( P = .011). Anterior cruciate ligament reconstruction occurred more commonly in the medial group, and cartilage procedures occurred more commonly in the lateral group. Conclusion: The clinical results of the lateral group were not different from those of the medial group. More graft extrusion was found in the medial group on MRI, and second-look arthroscopic surgery results of the lateral group were not as good as those of the medial group. The VAS and Lysholm scores of the combined group were worse than those of the isolated group. With regard to concomitant surgery, ACL reconstruction was most common in the medial group and cartilage procedures in the lateral group.
Mature Trauma Intensivist Model Improves Intensive Care Unit Efficiency But Not Mortality
Authors: Lee John , Rogers Frederick , Rogers Amelia , Horst Michael , Chandler Roxanne , Miller Jo Ann 
Published: November 2013

Background: Although the Leap Frog intensivist staffing model has been shown to improve outcomes in the intensive care unit (ICU), to date, no one has examined the effect of an intensivist model in a dedicated trauma ICU. With stricter adherence to evidence-based protocols and 24-hour availability, we hypothesized that a mature intensivist model in a trauma ICU would decrease mortality. Methods: Level II trauma center trauma ICU admissions 2006 to 2011. The ICU care provided by 6 trauma intensivists. Two periods were compared: early (2006-2008) and mature (2009-2011). Patients matched on age, Injury Severity Score (ISS), preexisting conditions, and so on in a univariate analysis, with significant variables placed in a logistic regression model, with mortality as the outcome. Results: A total of 3527 patients (2999 excluding do not resuscitate status) were reviewed. Age ≥65 (odds ratio [OR] 2.38, P < .001), ISS ≥17 (OR 3.3, P < .001), coagulopathy (OR 1.64, P = .004), and anemia (OR 1.73, P = .02) were independent predictors of mortality. Multivariate logistic model encompassing these factors found no statistically significant differences in mortality across the 6-year period. The ICU efficiency showed significant improvements in terms of ventilator days (30.1% EARLY vs 24.4% MATURE; P < .001), decreases in mean consultant use per patient (0.55 ± 0.85 EARLY vs 0.40 ± 0.74 MATURE; P < .001), and increase in number of bedside procedures per patient (0.09 ± 0.48 EARLY vs 0.40 ± 0.74 MATURE; P < .001 Conclusions: Our mature intensivists staffing model shows improvement in ICU throughput (ventilator days, ICU days, decreased consultant use, and increased bedside procedures) but no survival benefit. Further improvements in overall trauma mortality may lie in the resuscitative and operative phase of patient care.
Lower Hippocampal Volume Predicts Decrements in Lane Control Among Drivers With Amnestic Mild Cognitive Impairment
Authors: Griffith H. Randall , Okonkwo Ozioma C. , Stewart Christopher C. , Stoeckel Luke E. , Hollander Jan A. den , Elgin Jennifer M. , Harrell Lindy E. , Brockington John C. , Clark David G. , Ball Karlene K. , Owsley Cynthia , Marson Daniel C. , Wadley Virginia G. 
Published: November 2013

Objectives: There are few methods to discern driving risks in patients with early dementia and mild cognitive impairment (MCI). We aimed to determine whether structural magnetic resonance imaging (MRI) of the hippocampus—a biomarker of probable Alzheimer pathology and a measure of disease severity in those affected—is linked to objective ratings of on-road driving performance in older adults with and without amnestic MCI. Methods: In all, 49 consensus-diagnosed participants from an Alzheimer’s Disease Research Center (15 diagnosed with amnestic MCI and 34 demographically similar controls) underwent structural MRI and on-road driving assessments. Results: Mild atrophy of the left hippocampus was associated with less-than-optimal ratings in lane control but not with other discrete driving skills. Decrements in left hippocampal volume conferred higher risk for less-than-optimal lane control ratings in the patients with MCI (B = −1.63, standard error [SE] = .74, Wald = 4.85, P = .028), but not in controls (B = 0.13, SE = .415, Wald = 0.10, P = .752). The odds ratio and 95% confidence interval for below-optimal lane control in the MCI group was 4.41 (1.18-16.36), which was attenuated to 3.46 (0.88-13.60) after accounting for the contribution of left hippocampal volume. Conclusion: These findings suggest that there may be a link between hippocampal atrophy and difficulties with lane control in persons with amnestic MCI. Further study appears warranted to better discern patterns of brain atrophy in MCI and Alzheimer disease and whether these could be early markers of clinically meaningful driving risk.
Sir Archibald Hector McIndoe (1900–1960) and the Guinea Pig Club: The development of reconstructive surgery and rehabilitation in the Second World War (1939–1945)
Authors: Macnamara Alexandra F , Metcalfe Neil H 
Published: November 2013

Summary This article discusses the work of pioneering surgeon Sir Archibald McIndoe and particularly his reconstructive surgery and patient-centred approach during the Second World War. It also covers how this affected the lives of his patients and the subsequent formation of the Guinea Pig Club.
Systematic Review and Meta-Analysis of Balloon Angioplasty Versus Primary Stenting in the Infrapopliteal Disease
Authors: Yang Xinrui , Lu Xinwu , Ye Kaichuang , Li Xiangxiang , Qin Jinbao , Jiang Mier 
Published: November 2013

Objectives: We performed a systematic review and meta-analysis of comparing balloon angioplasty and primary stenting for symptomatic infrapopliteal disease to evaluate the clinical value of primary stenting in treating infrapopliteal diseases. Methods: Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines were followed. PubMed (1984-present), ScienceDirect (1980-present), Embase (1990-present), and CBM (1988-present) databases were searched for relevant articles. Finally, 16 studies (published between 2001 and 2013) satisfying the inclusion criteria were identified. The outcome parameters were immediate technical success, 1-year primary patency rate, 1-year limb salvage rate, and 1-year target vessel revascularization (TVR)-free rate. Comparisons were made with balloon angioplasty and primary stenting, and based on the different types of stents, we divided the primary stent group into the bare metal stent (BMS) group and drug-eluting stent (DES) group. Results: A total of 3789 patients and 4339 limbs constituted our final study population. The technical success rate of balloon angioplasty was 92.29% (95% confidence interval [CI] 88.75%-94.78%). Only 2 study reported the technical failure rates as 4% and 5.2% in the primary stent group. The pooled estimates of 1-year primary patency and TVR-free rate were similarly low in the balloon angioplasty group and BMS group (primary patency: 57.65%, 95% CI 53.54%-61.67% vs 60.95%, 95% CI 48.31%-72.28%, P = .38; TVR-free rate: 73.41%, 95% CI 66.51%-80.08% vs 73.66%, 95% CI 63.58%-81.75%, P = .91). The pooled estimates of 1-year primary patency and TVR-free rate in DES group were 81.10% (95% CI 75.48%-85.67%) and 90.30% (95% CI 85.30%-93.73%), respectively, which were better than those of the BMS and balloon angioplasty groups ( P < .001 for both). The pooled estimate of 1-year limb salvage in the balloon angioplasty, BMS, and DES groups was 88.61% (95% CI 85.01%-91.43%), 94.41% (95% CI 89.52%-97.1%), and 95.20% (95% CI 86.97%-98.33%), respectively ( P < .001). The BMS and DES groups had higher limb salvage rates than the balloon angioplasty group ( P < .001 for both comparisons). The rates of severe complications were low both in the balloon angioplasty and in the primary stent groups. Conclusion: Primary BMS implantation had no advantage over balloon angioplasty in reducing restenosis or revascularization for infrapopliteal disease. Primary DES implantation seems to be a promising treatment for focal infrapopliteal lesions. Publication bias could not be ruled out, and the results should be treated with caution.
Altitude Modulates Concussion Incidence
Authors: Smith David W. , Myer Gregory D. , Currie Dustin W. , Comstock R. Dawn , Clark Joseph F. , Bailes Julian E. 
Published: November 2013

Background: Recent research indicates that the volume and/or pressure of intracranial fluid, a physiology affected by one’s altitude (ie, elevation above sea level), may be associated with the likelihood and/or severity of a concussion. The objective was to employ an epidemiological field investigation to evaluate the relationship between altitude and concussion rate in high school sports. Hypothesis: Because of the physiologies that occur during acclimatization, including a decline in intracranial compliance (a “tighter fit”), increased altitude may be related to a reduction in concussion rates in high school athletes. Study Design: Cohort study; Level of evidence, 3. Methods: Data on concussions and athlete exposures (AEs) between 2005-2006 and 2011-2012 were obtained from a large national sample of high schools (National High School Sports-Related Injury Surveillance System [High School RIO]) and were used to calculate total, competition, and practice concussion rates for aggregated sports and for football only. Results: Altitude of participating schools ranged from 7 to 6903 ft (median, 600 ft), and a total of 5936 concussions occurred in 20,618,915 exposures (2.88 per 10,000 AEs). When concussion rates were dichotomized by altitude using the median, elevated altitude was associated with a reduction in concussion rates overall (rate ratio [RR], 1.31; P < .001), in competition (RR, 1.31; P < .001), and in practice (RR, 1.29; P < .001). Specifically, high school sports played at higher altitude demonstrated a 31% reduction (95% confidence interval [CI], 25%-38%) in the incidence of total reported concussions. Likewise, concussion rates at increased altitude were reduced 30% for overall exposures, 27% for competition exposures, and 28% for practice exposures in football players ( P < .001). Conclusion: The results of this epidemiological investigation indicate increased physiological responses to altitude may be associated with a reduction in sports-related concussion rates, especially in collision sports. Future research that focuses on the potential prophylactic effect of optimizing outflow impedance and thus reduction of intracranial compliance (a “tighter fit”) in humans is warranted to determine the most effective approaches to mitigate sport-related concussion, especially in football players.
Human proT-cells generated in vitro facilitate hematopoietic stem cell-derived T-lymphopoiesis in vivo and restore thymic architecture
Authors: Awong Génève , Singh Jastaranpreet , Mohtashami Mahmood , Malm Maria , La Motte-Mohs Ross N. , Benveniste Patricia M. , Serra Pablo , Herer Elaine , van den Brink Marcel R. , Zúñiga-Pflücker Juan Carlos 
Published: November 2013

Key PointsIntrathymic T-cell regeneration is facilitated by human proT-cells generated in vitro. In vitro–generated human proT-cells home to the thymus, wherein they restore thymic structure.
Chromatin looping defines expression of TAL1, its flanking genes, and regulation in T-ALL
Authors: Zhou Yan , Kurukuti Sreenivasulu , Saffrey Peter , Vukovic Milica , Michie Alison M. , Strogantsev Ruslan , West Adam G. , Vetrie David 
Published: November 2013

Key Points
GATA1-dependent chromatin looping at the TAL1 locus accounts for many biological and evolutionary features of TAL1 expression. Chromatin looping also regulates expression of TAL1 flanking genes and brings TAL1 and STIL into close proximity at T-ALL breakpoints.
How I treat nodular lymphocyte predominant Hodgkin lymphoma
Authors: Advani Ranjana H. , Hoppe Richard T. 
Published: November 2013

AbstractNodular lymphocyte predominant Hodgkin lymphoma (NLPHL) is an uncommon entity that, in contrast to classical Hodgkin lymphoma (cHL), universally expresses CD20, a hallmark of the disease. The majority of the patients present with early-stage disease, and treatment with local radiation provides excellent disease control and overall survival (OS). For locally extensive or advanced stages, paradigms used for cHL have been employed, with similar outcomes. Unlike cHL, late relapses may occur, as well as a propensity to transform to an aggressive B-cell non-Hodgkin lymphoma that underscores the importance of long-term follow-up and rebiopsy at the time of relapse. Deaths caused by NLPHL are uncommon, and in older series, secondary malignancies and other treatment-related toxicities contributed appreciably to overall mortality. Expression of CD20 in NLPHL has led to the evaluation of rituximab as a therapeutic option. Although results with single-agent rituximab in the front-line setting are inferior to conventional therapy, rituximab is a reasonable choice for relapsed disease because of the high overall response rate and excellent tolerability. Most patients have a long OS; therefore, overall goals of therapy should be to minimize the risk for relapse and long-term toxicity.
Comparative incidence of pregnancy outcomes in treated obstetric antiphospholipid syndrome: the NOH-APS observational study
Authors: Bouvier Sylvie , Cochery-Nouvellon Éva , Lavigne-Lissalde Géraldine , Mercier Érick , Marchetti Tess , Balducchi Jean-Pierre , Marès Pierre , Gris Jean-Christophe 
Published: November 2013

Key PointsAmong women with pure obstetric APS, late pregnancy complications are more frequent in cases of prior fetal loss. Late pregnancy complications are more frequent among women treated for pure obstetric APS than among nontreated controls.
Existence and uniqueness of a common fixed point under a limit contractive condition
Authors: Imdad Mohammad , Chauhan Sunny , Khan Muhammad Alamgir 
Published: November 2013

Abstract
In this paper, utilizing the notion of common limit range property for two pairs of self mappings, we prove common fixed point theorems in fuzzy metric spaces under a limit contractive condition, which improve and extend the results of Zhu et al. [Common fixed point theorems of new contractive conditions in fuzzy metric spaces, J. Appl. Math. 2013:145190, 2013]. We also give some examples to demonstrate the validity of the hypotheses of our results. As an application to our main result, we obtain a fixed point theorem for four finite families of self mappings in fuzzy metric space.

MSC: 47H10, 54H25.
Estimating the polygamma functions for negative integers
Authors: Salem Ahmed , Kılıçman Adem 
Published: November 2013

Abstract
The polygamma functions

ψ

(
r
)

(
x
)

are defined for all

x
>
0

and

r
∈
N

. In this paper, the concepts of neutrix and neutrix limit are applied to generalize and redefine the polygamma functions

ψ

(
r
)

(
x
)

for all

x
∈
R

and

r
∈
N

. Also, further results are given.

MSC:33B15, 46F10.