bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of antibacterial activity of selected plant extracts against Serratia marcescens
Authors: Singh Gagandeep , Parihar Akanksha Singh , Sharma Vishakha , Tandon Smriti , Bhagwat Prateeksha , Yadav Sunanda , Grewal Jyotika , Rawat Hemant , Singh Virendra , Narasimhaji Ch. Venkata , Soni Hemant , Srikanth Narayanam , Acharya Rabinarayan 
Published: July 2024

Abstract

BACKGROUND:

Serratia marcescens is a well-known Gram-negative, rod-shaped bacterium commonly found in soil, animal skin, hospital environment, and plant-based raw materials. It is an opportunistic pathogen that causes serious infections, including pneumonia, bloodstream infection, wound infection, meningitis, and respiratory and urinary tract infections. Due to multiple resistant strains of S. marcescens being identified, new and effective plant-based antimicrobial compounds/drugs against S. marcescens must be searched. The present study is focused to explore the Stem of Neem (Azadirachta indica), Seed of Nirgundi (Vitex negundo) and Clove buds (Syzygium aromaticum) for their antibacterial activity against the isolated S. marcescens.

METHODS:
The S. marcescens was isolated from the garden soil of CARI Jhansi and identified based on various morphological and biochemical tests. We also checked the antibiotic profile of isolated S. marcescens. The ethanolic and methanolic extracts of the selected plant parts were prepared and explored for their antibacterial activity against S. marcescens using the disc diffusion method.

RESULTS:
The antibiotic profile of S. marcescens showed resistance to multiple broad-spectrum antibiotics, including erythromycin, rifampicin, chloramphenicol, and narrow-spectrum antibiotic vancomycin. At the same time, it was sensitive to kanamycin, streptomycin, ciprofloxacin, and ofloxacin. We observed that both methanolic and ethanolic extracts of clove buds were effective, while only the ethanolic extract of Nirgundi seed and Neem stem were found to be effective against S. marcescens.

CONCLUSION:
From this study, we conclude that both methanolic and ethanolic extracts of Clove buds, while only the ethanolic extract of Nirgundi seed and Neem stem, were found effective and showed significant inhibition of growth of S. marcescens.
Mitigation of testicular damage induced by DMBA/TPA through Murraya koenigii (L.) Spreng.: Insights into antioxidant and anti-apoptotic mechanisms
Authors: Kaur Sarvnarinder , Aniqa Aniqa , Kumar Sunil , Sadwal Shilpa 
Published: July 2024

Abstract

BACKGROUND:
7,12-Dimethylbenz[a]anthracene (DMBA) is a known mutagen, teratogen, and toxicant besides being a significant factor responsible for skin carcinogenesis. During carcinogenesis, DMBA and its metabolites produce excessive free radicals and oxidative stress. This oxidative stress further targets various cell organelles. Consequences of the damage by DMBA also influence vital organs, such as the brain, liver, and testis, with complex reactions, such as an increase in mutation, modification in cell membranes, structural proteins, metabolic enzymes, and signaling proteins. Therefore, this study evaluated the possible role of hydroethanolic Murraya koenigii (L.) Spreng. leaves extract (HEMKLE) upon damages incurred in testis tissues against DMBA/12-O-tetradecanoyl phorbol-13-acetate (TPA) in skin tumor-bearing mice.

METHODS:
Forty male LACA mice were segregated into four groups: control, DMBA/TPA, HEMKLE, and HEMKLE + DMBA/TPA. Skin tumors were induced by DMBA (500 nmol/100 μL of acetone) and TPA (1.7 nmol/100 μL of acetone; applied topically).

RESULTS:
The protective response of HEMKLE (200 mg/kg body weight) to testicular damage during skin tumorigenesis was apparent by recovery of endogenous antioxidant enzymes, along with histoarchitecture in the HEMKLE + DMBA/TPA group contrasted with the DMBA/TPA group. Furthermore, in the HEMKLE + DMBA/TPA group, reduced messenger ribonucleic acid and protein expressions of proapoptotic genes (caspase-9 and caspase-3) and enhancement in Bcl-2 were observed, proposing the anti-apoptotic potential of HEMKLE in testicular tissues.

CONCLUSION:
HEMKLE could be used as a nutraceutical or antioxidant drug to protect the body from testicular insults.
Exploring the link between eustress and adolescent health in India: An empirical study
Authors: Saini Reena , Arora Astha , Joshi Hardeep , Gaurav Alok K. 
Published: July 2024

BACKGROUND:
Modern psychological research challenges the conventional view of stress as solely detrimental by introducing the concept of eustress versus distress, emphasizing the potentially positive aspects of stress. In the context of India, limited studies have investigated the distinct effects of eustress and distress on adolescents, a group prone to stress-related health issues. This study aims to bridge this gap by examining the correlation between eustress and both mental and physical well-being among adolescents attending government schools in two districts of Haryana, India.

MATERIALS AND METHODS:
A non-experimental quantitative research approach was adopted to achieve this objective. The study involved a sample of 400 adolescent students, equally split between genders, aged 15 to 18 years, enrolled in grades 10 to 12. Participants were selected through systematic random sampling from two districts in Haryana. The assessment tools employed in the study included the Post Graduate Institute Health Questionnaire and the Eustress Scale, which were utilized to evaluate the participants’ mental, physical, and eustress levels.

RESULTS:
In our study involving Indian adolescents, we discovered a substantial positive correlation (r = 0.563, P < 0.01) between eustress and mental health, underlining the valuable role of positive stress in enhancing psychological well-being. Notably, male participants exhibited significantly higher eustress scores (mean = 26.63) than their female counterparts (mean = 22.82, P < 0.01), indicating gender-specific variations in stress responses. Furthermore, our findings emphasized the influence of cultural nuances inherent to the Indian context on how adolescents perceived and experienced eustress. These outcomes emphasize the urgency of culturally sensitive interventions to promote adolescents’ well-being.

CONCLUSION:
This investigation contributes valuable insights into the nexus between eustress and adolescent health in the Indian context. The study accentuates the potential advantages of leveraging eustress to foster positive development by underlining the differential influence of eustress and distress on adolescent health. Future research endeavors and policy formulation could delve into the mechanisms underpinning eustress and distress, thus guiding strategies to enhance adolescents’ health and overall well-being.
Impact of COVID-19 pandemic on the mental health status among general masses: An in-deep analysis of the worst “hitters” of COVID-19 pandemic
Authors: Rangarajan Priyadarshni , Sultana Shaik F. , Punnoose Kurian , Ahmed Hina , Singh Gautam , Kiruthika V. , Babu Suresh J. , Swarnalatha C. , Nayyar Abhishek Singh 
Published: July 2024

BACKGROUND:
A plethora of studies have reported the adverse psychiatric outcomes among the general masses during the COVID-19 pandemic; however, not much data is available in relation to the Indian population from this perspective. The aim of the present study was to investigate the impact of the COVID-19 pandemic on the mental health status among the general masses in the Indian population.

MATERIALS AND METHODS:
The present study was planned in a cross-sectional study design between July 2020 and October 2021 in which a well-structured questionnaire, consisting of questions assessing the sociodemographic profile, while, also, specific questions related to the stress and anxiety-related variables, was used. The questionnaire was validated through intra-class correlation with a strong correlation of 0.84. The Chi-square test was used for statistical analysis to test the association between the studied variables, while P < 0.05 was considered statistically significant.

RESULTS:
On comparison between the male and female participants using stress and anxiety-related variables, 43.81% of males as against 56.19% of the female participants reported that they felt horrified due to the pandemic with the results being statistically highly significant (P = 0.0043). Similarly, 45.18% of male and 54.82% of female participants expressed apprehension due to the fear of the pandemic with the results being statistically significant (P = 0.0217).

CONCLUSION:
The research findings of the present study indicated that men and women responded to stress differently, with women experiencing greater sadness and anxiety and were found to be at a relatively greater risk for developing anxiety and depression than men.
Body composition, cardiovascular fitness and attention of school-aged male children practicing sports club activities: A cross-sectional
Authors: Ates Bahar , Tanir Halil , Akinci Yasin 
Published: July 2024

BACKGROUND:
The positive effects of physical activity on physical fitness, bone health, academic achievement, cognitive functions, mental health, and reduced obesity have been proven. This study aims to investigate the relationship between sports club activities, physical activity selected health-related fitness, and the d2 attention test.

MATERIALS AND METHODS:
A cross-sectional study was conducted in different sports clubs. A total of 78 male students aged 10-13 years participating in various branches of sports clubs were included in the study, 42 of whom were assigned to the sports group and 36 to the control group. Questionnaires were administered to assess sports club participation and attention levels, while physical health profiles were tested with body composition and Yo-Yo IR1C performance measures. Data were analyzed according to sports participation and the five most frequently reported sports. The means and standard deviation of each study value were calculated for the total subjects and by participating in sports activity using the IBM SPSS (version 23) analysis program. Data normality was checked and confirmed by the Skewness and Kurtosis Tests.

RESULTS:
The results showed that boys enrolled in a sports activity had lower body mass (-17.9%, P < 0.05 d = 0.72), body mass index (-13.4%, P < 0.05, d = 0.87), and body fat (%) (-54.1%, P < 0.05, d = 1.38) and higher VO2max 32.3% (P < 0.05, d = 3.67), than the non-active group. The boys active in sports clubs also had better results in the total number of items processed (11%, P < 0.05 d = 0.50) and in concentration performance (17.7%, P < 0.05 d = 0.56) than the non-active group. In correlation analyses, VO2max was negatively associated with body mass, body mass index, and body fat (P = 0.011; P = 0.001 and P = 0.00, respectively) and positively related to the total number of items processed and concentration performance (P = 0.003 and P = 0.015, respectively). In the Pearson Correlation analyses, body fat showed a lower negative correlation with TN (r = 0.33; P = 0.003) and CP (r = 0.28; P = 0.015).

CONCLUSIONS:
Boys participating in regular sports have lower body mass, BMI, and BF values. In addition, boys who participated in sports showed higher imaginary fitness and selective attention and concentration capacity results, as expected, for any sports part compared to their body peers. Another attempt from this study is that body mass and body fat percentage recovery are negatively associated with fitness. Considering the increasing prevalence of obesity in children and adolescents due to sedentary living, which has become a worldwide epidemic, it is recommended that pedagogical and public health strategies and policies be developed based on the physical fitness level of children.
Weight bias internalization and its association with psychological distress and weight-related factors among youths in university, Thailand
Authors: Yangyuen Suneerat , Somdee Thidarat , Yin Meihua , Chaichan Atchara 
Published: July 2024

BACKGROUND:
Weight bias internalization (WBI) is associated with poor weight-related health and psychological health problems in adults. However, less is known about WBI in Thai youths, and its associated factors are scarce. This study aimed to assess the association between psychological, weight-related factors, and WBI among Thai youths.

MATERIALS AND METHODS:
A cross-sectional design was conducted on 1185 university youths from three universities in northeastern, Thailand from January to June 2023, with multistage sampling methods. The data were collected by self-administered questionnaire. Multinomial logistic regression was applied to explore factors that influence WBI.

RESULTS:
Most of the youth were female; with the average body mass index (BMI) was 23.3 ± 3.2 kg/m2. More than half (n = 628; 52.9%) of them reported a high level of WBI that was present across the weight spectrum. Approximately 41.4% (n = 490) reported being dissatisfied with their body image, and 50.6% (n = 600) had peers with obesity. WBI was positively related to depressive symptoms, perceived stress, the experience of weight stigma, BMI, and body image dissatisfaction. Conversely, it was negatively related to self-esteem and peers with obesity.

CONCLUSION:
WBI is influenced by several psychological and weight-related factors. Additionally, youths across body weight categories could be vulnerable to high WBI. Hence, consideration of these potential factors could be useful in designing targeted interventions to reduce WBI.
Prevalence and factors associated with the poor quality of sleep among Indian nurses
Authors: Kaur Jasneet , Upendra Sheela , Barde Sheetal 
Published: July 2024

BACKGROUND:
Nursing health workers deal with a variety of issues that may have an unfavorable influence on their capability to peaceful sleep. The consequences of poor quality of the sleep can lead to increased fatigue, decreased concentration, and a higher risk of medical and nursing errors. The purpose of this research study was to determine in the occurrence and associated factors for poor quality of the sleep among Indian nurses.

MATERIALS AND METHODS:
The participants in this cross-sectional study were selected by the use of a multi-stage sampling technique. A total of 25 hospitals (across 4 zones) were randomly sampled. A total of 850 (out of 1250) nurses participated in the study. To collect socio-demographic data, a self-administered questionnaire was employed. PSQI scale was implemented to assess quality of sleep, and the other scale of DASS-21 was used to assess mental well-being.

RESULTS:
The majority of nurses had mild (6–7 hours) as well as moderate (5–6 hours) levels of difficulty in the duration of sleep time. The occurrence of poor quality of the sleep in nursing professionals is high. 9.2% had depression, 13.7% had anxiety, and 18.9% faced, which appears to be linked to insufficient sleep in the adjusted model. In the univariate study, additional night shifts and additional shift hours were substantially related to insufficient sleep.

CONCLUSION:
Nurses’ quality of sleep is substantially hampered due to various reasons, and nurse mangers should devise the framework to avoid its harmful effects and to provide desirable management and high-quality patient care.
Impact of sleep deprivation on stress levels and cognitive performance in young and middle-aged adults at a Medical University in Ajman, UAE
Authors: Shaikh Shaman A. , Alintakli Farid , Mohamed Moustafa , Mohammed Masud , Khanam Razia , Shetty Preetha J. 
Published: July 2024

BACKGROUND:
Inadequate sleep is a widespread public health concern, impacting physical and mental health, as well as cognitive well-being. This study explores the link between sleep quality, the inflammatory marker interleukin-6 (IL-6), and cognitive function in two age groups (18-25 years and 35 years and above) at Gulf Medical University.

MATERIALS AND METHODS:
Sleep quality was assessed using the Pittsburgh questionnaire, and salivary IL-6 levels were measured. Cognitive function was evaluated using the National Aeronautics and Space Administration-Psychomotor Vigilance Test (NASA-PVT), focusing on mean reaction time (RT), lapses, fastest 10% RT, and slowest 10% RT. Descriptive and inferential statistics were used to analyze the data. The descriptive statistics used were frequency, percentage mean, and standard deviation (SD). The inferential statistics used was the unpaired t-test. The level of significance was taken as P ≤ 0.05. Statistical Package for the Social Sciences (SPSS) 28 was used to analyze the data.

RESULTS:
Approximately 75% of young adults and 80% of middle-aged adults reported good sleep quality. Sleep disturbances were reported by 65% of young adults and 95% of middle-aged adults. In both age groups, individuals with poor sleep exhibited higher IL-6 levels, but all IL-6 values remained within the reference range. NASA-PVT results indicated that individuals with poor sleep had higher mean RT and lapses compared to those with good sleep. In the older age group, both mean RT and lapses were higher than in the younger group, suggesting potential age-related effects on psychomotor vigilance.

CONCLUSION:
Our findings suggest a connection between poor sleep quality, elevated IL-6 levels, and impaired cognitive performance.
Adherence to the Mediterranean diet and sleep quality are inter-correlated with flash glucose monitoring (FGM)-measured glycemia among children with type 1 diabetes
Authors: Muayyad Mariam , Abusnana Salah , Mussa Bashair M. , Helal Radwa , Abdelrahim Dana N. , Abdelreheim Naguib Hassan , Al Amiri Elham , Daboul Mays , Al-Abadla Zainab , Lessan Nader , Faris MoezAlIslam E. 
Published: July 2024

BACKGROUND:
We examined the inter-correlation between diet quality, objectively measured sleep duration, and subjectively measured sleep quality with flash glucose monitoring (FGM)-measured glycemia among young patients with type 1 diabetes (T1D).

MATERIALS AND METHODS:
Following cross-sectional design, Fitbit® accelerometers were used to objectively assess sleep duration, while the validated questionnaires Pittsburgh sleep quality index and Mediterranean diet (MD) adherence were used to subjectively assess sleep quality and diet quality, respectively. Glycated hemoglobin (HbA1c) and FGM-reported glycemia components among children with T1D were assessed as well.

RESULTS:
Of the 47 participants surveyed (25 boys, 22 girls, 9.31 ± 2.88 years), the majority reported high HbA1c, good sleep quality, and high adherence to the MD. However, only one-third of the participants reported a healthy sleep duration. Only the sleep latency was significantly (P < 0.05) associated with the time above range level 2 and time below range level 2 (P = 0.048) components of the FGM. A positive correlation (r = 0.309, P = 0.035) was reported between adherence to MD and time in range of the FGM.

CONCLUSIONS:
Diet quality and sleep quality are variably inter-correlated with FGM-measured glycemia among young patients with T1D and are suggested to be considered influential factors in FGM-monitored diabetes research on this age group.
Stress levels and eating behavior among university students in Jordan: A cross-sectional study
Authors: AL-Dalaeen Anfal , Batarseh Nour , Al-Bashabsheh Zaher , ALjeradat Baha’Ghandi , Batarseh Dima , Karablieh Arab 
Published: July 2024

BACKGROUND:
Increased body weight is common among university students; transitioning from high school to university may increase perceived stress levels, thus changing dietary habits and metabolism to promote overweight or obesity. The current study investigates the association between stress and dietary habits among university students in Jordan.

MATERIALS AND METHODS:
A cross-sectional study was conducted among 221 university students aged between 20 and 25 at Applied Science Private University [ASU]. A self-reported questionnaire was distributed to university students. The questionnaires were divided into three sections: the first was about general characteristics, body weight, change in body weight, and stress eating.

RESULT:
The survey of 208 participants showed that 64.3% were females, and 84.2% of students lived with their families. Results showed that more than half [51.1%] of the respondents were dissatisfied with their eating habits. Females [57.7%] monitored their food intake more than males did. However, most males [77.2%] reported less eating during stress compared to females. In addition, the data analysis revealed that those who ate more were less likely to monitor their food intake [χ
2 =9.734, df = 1, P = .002] or quantity [χ
2 =16.704, df = 1, P < .001]. Only 20.8% of the participants preferred sports or hobbies as a stress reduction activity; 29.4% took showers, while 51.1% ignored what made them stressed. Finally, 56.3% of participants reported increased weight after starting university, and it was significantly correlated with stress eating while studying for exams [χ
2 =8.762, df = 2, P = .013]. Stress affects university students and can lead to unhealthy eating habits and health issues like obesity.

CONCLUSION:
Many students face stress during their academic years, which affects their dietary choices. Policies promoting healthy eating habits and stress-reducing activities are important for university students.
Compare the effectiveness of two treatments, behavioral activation and acceptance and commitment therapy, on depression and mental rumination in mothers of children with cerebral palsy in Ilam city
Authors: Alirahmi Mostafa , Kikhavani Sattar , Soleimannejad Homeira 
Published: July 2024

BACKGROUND:
Since in most families, mothers are more responsible for taking care of children and have more responsibility than fathers for monitoring the child, taking care of a disabled child can have a more negative effect on the psychological state of mothers. This study aimed to investigate the effectiveness of behavioral activation (BA) and acceptance and commitment therapy (ACT) in depression and rumination in mothers with children with cerebral palsy.

MATERIALS AND METHODS:
This research was quasi-experimental field research with a pre-posttest and control group. The study population comprised 237 mothers with children who had cerebral palsy and were referred to occupational therapy centers in Ilam, Iran. The sample consisted of 60 participants selected by convenience sampling, who were randomly divided into two experimental groups (BA and ACT) and a control group (n = 20 per group). Data were analyzed using Statistical Package for the Social Sciences (SPSS) version 27.0 with descriptive and inferential statistics, such as mean, standard deviation, and multivariate analysis of covariance (MANCOVA).

RESULTS:
The results of both BA and ACT were effective in reducing depression (P < 0.01) and rumination (P < 0.01) in the two experimental groups compared with the control group in the posttest phase. Furthermore, the effectiveness of the ACT in reducing depression and rumination was found to be more significant than the effectiveness of BA (P ≤ 0.05).

CONCLUSION:
The findings of the study suggest that both BA and ACT are effective in reducing depression and rumination in the research participants. However, the study also found that ACT was more effective than BA in reducing depression and rumination. Thus, both approaches can be used to strengthen treatment interventions to lessen depression and rumination in the research participants.