bluuebunny/crossref_metadata_2025_split huggingface dataset:
SAT‐OFDM: a satellite radio interface for the IMT‐advanced system
Authors: Kim Hee Wook , Kang Kunseok , Ku Bon‐Jun , Chang Dae‐Ig , Kim Sooyoung 
Published: April 2015

SummaryThis paper presents the satellite orthogonal frequency division multiplexing (SAT‐OFDM) technology as a satellite radio interface for international mobile telecommunications (IMT)‐Advanced. The SAT‐OFDM radio interface is designed to provide various advanced IMT services in satellite environments. For cost‐effective deployment of a satellite IMT‐Advanced system, the radio interface must have a high degree of commonality with third‐generation partnership project long‐term evolution (3GPP LTE) technology for IMT‐Advanced, but it also has a number of different features. Those features are needed to adapt the 3GPP LTE technology for satellite‐specific environments such as long round‐trip delay, large cell size, and slow‐fading satellite channel. In this paper, we summarize the key features of the SAT‐OFDM technology and propose satellite specific features included in the SAT‐OFDM technology as an adaption way of LTE over satellite. Then we show the performance evaluation results of the SAT‐OFDM technology to see the feasibility of LTE over satellite. Copyright © 2015 John Wiley & Sons, Ltd.
The psychology of appraisal: Specific emotions and decision‐making
Authors: So Jane , Achar Chethana , Han DaHee , Agrawal Nidhi , Duhachek Adam , Maheswaran Durairaj 
Published: April 2015

AbstractA growing stream of research has examined emotions and decision‐making based on the appraisal tendencies associated with emotions. This paper outlines two general approaches that can lead to further our understanding of the variety of ways emotions affect decision‐making and information processing. Specifically, future research can examine the nature of emotional appraisals or investigate the nature of decision contexts and underlying psychological processes influenced by emotions. To understand the nature of emotional appraisals, scholars could examine the interaction of two appraisal dimensions or identify novel appraisal tendencies. To understand the decision‐making contexts and psychological processes influenced by emotions, scholars could examine how emotions interact with contextual influences to shape judgments through a variety of processes such as providing information, priming goals, or activating mindsets. These approaches to the study of emotions and decision‐making will contribute to more nuanced theory development around emotions, nurture new empirical work, and encourage interest in exploring a broader set of emotions.
Ablation of an atriofascicular accessory pathway with a zero‐fluoroscopy procedure
Authors: Proietti Riccardo , Abadir Sylvia , Bernier Martin L. , Essebag Vidal 
Published: April 2015

AbstractA 16‐year‐old patient with recurrent palpitations and documented left bundle branch block superior axis wide complex tachycardia underwent an electrophysiological study and ablation with a zero‐fluoroscopy procedure. The electrophysiological study showed a decremental antegrade conducting atriofascicular pathway. Three‐dimensional CARTO‐guided mapping of the tricuspid annulus in sinus rhythm was performed, and a distinct signal corresponding to the accessory pathway potential of the atriofascicular pathway was found in the posterolateral region. By using an SR0 sheath and a 4‐mm‐tip catheter, radiofrequency application was delivered at this point on the annulus and successfully eliminated conduction through the accessory pathway.
Temperature dependence of the inversion degree in three-cation spinel solid solutions: experimental evaluation by XRD
Authors: Podwórny Jacek 
Published: April 2015

The method of degree of inversion calculation presented in the present paper was based on the determination of several temperature-dependent parameters such as: oxygen positional parameter, lattice parameter, cation site occupancies, and a cation–anion distance in tetrahedral and octahedral sites. The theoretical basis of the method as well as the required derivation of formulae and the conditions of its application has been described.The values of the measured temperature-dependent parameters were used to calculate the degree of inversion vs. temperature in the spinel structure. Initial temperatures of the order–disorder transformation were determined. The described method of investigating the order–disorder phase transformation based on three examples of spinel solid solutions: Mg(Al0.5Fe0.5)2O4, (Mg0.75Ni0.25)Al2O4, and (Mg0.75Co0.25)Al2O4 has been presented. Investigations by means of the high-temperature X-ray diffraction method at temperatures ranging from 25 to 1100 °C were carried out. It has been shown that using the present method, it is possible to determine the distribution of each cation in tetrahedral and octahedral sites at each temperature. In consequence, the unidirectional order–disorder phase transformation as well the bidirectional transformation in the spinel structure can be investigated. The advantages and disadvantages of the method have been discussed and its uncertainties presented.
Predictors of Adolescents’ Consent to Use Health Records for Research and Results from Data Collection in a Swedish Twin Cohort
Authors: Ullemar Vilhelmina , Lundholm Cecilia , Örtqvist Anne K. , Gumpert Clara Hellner , Anckarsäter Henrik , Lundström Sebastian , Almqvist Catarina 
Published: April 2015

Introduction:Non-random selection into a study population due to differences between consenters and non-consenters may introduce participation bias. Past investigations of factors predicting consent to collection of medical health records for research imply that age, sex, health status, and education are of importance for participation, but disagree on the direction of effects. Very little is known about influences on consent from adolescents.Methods:Two cohorts of Swedish 15-year-old twins (totaln= 4,611) previously invited to the Child and Adolescent Twin Study in Sweden (CATSS) responded to a questionnaire with information on sex, individual's health, height, weight, and parental factors. The questionnaire included a question for consent to collection of medical health records. Predictors for consent were analyzed using logistic regression. Additionally, regional differences in the collection of health records of consenters were evaluated.Results:Males were significantly less likely to consent compared to females (OR 0.74, 95% CI 0.64–0.85). The twin siblings’ decision to consent was strongly associated with consent (OR 10.9, 95% CI 8.76–13.5), and individuals whose parents had responded to the original CATSS study were more likely to consent to record collection at age 15 (OR 2.2, 95% CI 1.81–2.75). Results of the subsequent collection of consenters’ medical health records varied between geographical regions of Sweden.Conclusion:We identified several predictors for adolescents’ consent to collection of their medical health records. Further selection was introduced through the subsequent record collection. Whether this will induce participation bias in future studies depends on the research questions’ relationship to the identified predictors.
Tunable solid-state fluorescent materials for supramolecular encryption
Authors: Hou Xisen , Ke Chenfeng , Bruns Carson J. , McGonigal Paul R. , Pettman Roger B. , Stoddart J. Fraser 
Published: April 2015

AbstractTunable solid-state fluorescent materials are ideal for applications in security printing technologies. A document possesses a high level of security if its encrypted information can be authenticated without being decoded, while also being resistant to counterfeiting. Herein, we describe a heterorotaxane with tunable solid-state fluorescent emissions enabled through reversible manipulation of its aggregation by supramolecular encapsulation. The dynamic nature of this fluorescent material is based on a complex set of equilibria, whose fluorescence output depends non-linearly on the chemical inputs and the composition of the paper. By applying this system in fluorescent security inks, the information encoded in polychromic images can be protected in such a way that it is close to impossible to reverse engineer, as well as being easy to verify. This system constitutes a unique application of responsive complex equilibria in the form of a cryptographic algorithm that protects valuable information printed using tunable solid-state fluorescent materials.
Crystal structure of a mirror-image L-RNA aptamer (Spiegelmer) in complex with the natural L-protein target CCL2
Authors: Oberthür Dominik , Achenbach John , Gabdulkhakov Azat , Buchner Klaus , Maasch Christian , Falke Sven , Rehders Dirk , Klussmann Sven , Betzel Christian 
Published: April 2015

AbstractWe report the crystal structure of a 40mer mirror-image RNA oligonucleotide completely built from nucleotides of the non-natural L-chirality in complex with the pro-inflammatory chemokine L-CLL2 (monocyte chemoattractant protein-1), a natural protein composed of regular L-amino acids. The L-oligonucleotide is an L-aptamer (a Spiegelmer) identified to bind L-CCL2 with high affinity, thereby neutralizing the chemokine’s activity. CCL2 plays a key role in attracting and positioning monocytes; its overexpression in several inflammatory diseases makes CCL2 an interesting pharmacological target. The PEGylated form of the L-aptamer, NOX-E36 (emapticap pegol), already showed promising efficacy in clinical Phase II studies conducted in diabetic nephropathy patients. The structure of the L-oligonucleotide·L-protein complex was solved and refined to 2.05 Å. It unveils the L-aptamer’s intramolecular contacts and permits a detailed analysis of its structure–function relationship. Furthermore, the analysis of the intermolecular drug–target interactions reveals insight into the selectivity of the L-aptamer for certain related chemokines.
Two-dimensional gold nanostructures with high activity for selective oxidation of carbon–hydrogen bonds
Authors: Wang Liang , Zhu Yihan , Wang Jian-Qiang , Liu Fudong , Huang Jianfeng , Meng Xiangju , Basset Jean-Marie , Han Yu , Xiao Feng-Shou 
Published: April 2015

AbstractEfficient synthesis of stable two-dimensional (2D) noble metal catalysts is a challenging topic. Here we report the facile synthesis of 2D gold nanosheets via a wet chemistry method, by using layered double hydroxide as the template. Detailed characterization with electron microscopy and X-ray photoelectron spectroscopy demonstrates that the nanosheets are negatively charged and [001] oriented with thicknesses varying from single to a few atomic layers. X-ray absorption spectroscopy reveals unusually low gold–gold coordination numbers. These gold nanosheets exhibit high catalytic activity and stability in the solvent-free selective oxidation of carbon–hydrogen bonds with molecular oxygen.
Radical cascade reaction of alkynes with N-fluoroarylsulfonimides and alcohols
Authors: Zheng Guangfan , Li Yan , Han Jingjie , Xiong Tao , Zhang Qian 
Published: April 2015

AbstractCascade reactions initiated by radical addition to alkynes are synthetically very attractive because they enable access to highly complex molecular skeletons in only few synthetic steps under usually mild conditions. Here we report a general radical cascade reaction of alkynes, N-fluoroarylsulfonimides and alcohols, enabling the efficient synthesis of important α-amino-α-aryl ketones from readily available starting materials via a single operation. During this process, the highly regioselective nitrogen-centred radical addition to internal and terminal alkynes generating vinyl radicals and the next explicit migration of aryl group from the nitrogen source lead the following efficient desulfonylation, oxygenation, and semi-pinacol rearrangement. In addition, the semi-pinacol rearrangement precursors, α-alkyloxyl-α,α-diaryl imines, could also be efficiently obtained under milder conditions. This methodology might open a new entry for designing intermolecular radical cascade reaction of alkynes.
Hypothermic temperature effects on organ survival and restoration
Authors: Ishikawa Jun , Oshima Masamitsu , Iwasaki Fumitaka , Suzuki Ryoji , Park Joonhong , Nakao Kazuhisa , Matsuzawa-Adachi Yuki , Mizutsuki Taro , Kobayashi Ayaka , Abe Yuta , Kobayashi Eiji , Tezuka Katsunari , Tsuji Takashi 
Published: April 2015

AbstractA three-dimensional multicellular organism maintains the biological functions of life support by using the blood circulation to transport oxygen and nutrients and to regulate body temperature for intracellular enzymatic reactions. Donor organ transplantation using low-temperature storage is used as the fundamental treatment for dysfunctional organs. However, this approach has a serious problem in that donor organs maintain healthy conditions only during short-term storage. In this study, we developed a novel liver perfusion culture system based on biological metabolism that can maintain physiological functions, including albumin synthesis, bile secretion and urea production. This system also allows for the resurrection of a severely ischaemic liver. This study represents a significant advance for the development of an ex vivo organ perfusion system based on biological metabolism. It can be used not only to address donor organ shortages but also as the basis of future regenerative organ replacement therapy.
Direct ethanol production from starch using a natural isolate, Scheffersomyces shehatae: Toward consolidated bioprocessing
Authors: Tanimura Ayumi , Kikukawa Minako , Yamaguchi Shino , Kishino Shigenobu , Ogawa Jun , Shima Jun 
Published: April 2015

AbstractConsolidated bioprocessing (CBP), which integrates enzyme production, saccharification and fermentation into a one-step process, is a promising strategy for cost-effective ethanol production from starchy biomass. To gain insights into starch-based ethanol production using CBP, an extensive screening was undertaken to identify naturally occurring yeasts that produce ethanol without the addition of any amylases. Three yeast strains were capable of producing a significant amount of ethanol. Quantitative assays revealed that Scheffersomyces shehatae JCM 18690 was the strain showing the highest ethanol production ability. This strain was able to utilize starch directly and the ethanol concentration reached 9.21 g/L. We attribute the ethanol-producing ability of this strain to the high levels of glucoamylase activity, fermentation potential and ethanol stress tolerance. This study strongly suggests the possibility of starch-based ethanol production by consolidated bioprocessing using natural yeasts such as S. shehatae JCM 18690.
A Pure Inorganic ZnO-Co3O4 Overlapped Membrane for Efficient Oil/Water Emulsions Separation
Authors: Liu Na , Lin Xin , Zhang Weifeng , Cao Yingze , Chen Yuning , Feng Lin , Wei Yen 
Published: April 2015

AbstractThe earth's environmental problems, especially for water remediation, need effective methods to solve. Materials with special wettability are developed for the separation of oil/water mixtures. However, the separation of emulsified oil/water mixtures can be a real challenge. There is still much deficiencies, on account of the surfactant, which could link water molecules and oil molecules to form a stabilized system. Here we report a pure inorganic ZnO-Co3O4 overlapped membrane to give a brand new solution to emulsified oil/water mixture separation. Fabricated by an easy and cost-efficient way, such a membrane combines the properties of under-water superoleophobicity and under-oil superhydrophobicity, which can be successfully used for the efficient separation of both surfactant-free and surfactant-stabilized emulsions, solely driven by gravity. This ZnO-Co3O4 overlapped membrane shows great potential applications to industrial wastewater treatment, domestic sewage purification and other water remediation.
Prognostic value of pretreatment serum lactate dehydrogenase level in patients with solid tumors: a systematic review and meta-analysis
Authors: Zhang Jiao , Yao Yan-Hong , Li Bao-Guo , Yang Qing , Zhang Peng-Yu , Wang Hai-Tao 
Published: April 2015

AbstractAlthough most studies have reported that high serum lactate dehydrogenase (LDH) levels are associated with poor prognosis in several malignancies, the consistency and magnitude of the impact of LDH are unclear. We conducted the first comprehensive meta-analysis of the prognostic relevance of LDH in solid tumors. Overall survival (OS) was the primary outcome; progression-free survival (PFS) and disease-free survival (DFS) were secondary outcomes. We identified a total of 68 eligible studies that included 31,857 patients. High LDH was associated with a HR for OS of 1.48 (95% CI = 1.43 to 1.53; P < 0.00001; I2 = 93%), an effect observed in all disease subgroups, sites, stages and cutoff of LDH. HRs for PFS and DFS were 1.70 (95% CI = 1.44 to 2.01; P < 0.00001; I2 = 13%) and 1.86(95% CI = 1.15 to 3.01; P = 0.01; I2 = 88%), respectively. Analysis of LDH as a continuous variable showed poorer OS with increasing LDH (HR 2.11; 95% CI = 1.35 to 3.28). Sensitivity analyses showed there was no association between LDH cutoff and reported HR for OS. High LDH is associated with an adverse prognosis in many solid tumors and its additional prognostic and predictive value for clinical decision-making warrants further investigation.
Solitons shedding from Airy beams and bound states of breathing Airy solitons in nonlocal nonlinear media
Authors: Shen Ming , Gao Jinsong , Ge Lijuan 
Published: April 2015

AbstractWe investigate the spatially optical solitons shedding from Airy beams and anomalous interactions of Airy beams in nonlocal nonlinear media by means of direct numerical simulations. Numerical results show that nonlocality has profound effects on the propagation dynamics of the solitons shedding from the Airy beam. It is also shown that the strong nonlocality can support periodic intensity distribution of Airy beams with opposite bending directions. Nonlocality also provides a long-range attractive force between Airy beams, leading to the formation of stable bound states of both in-phase and out-of-phase breathing Airy solitons which always repel in local media.
Red Queen dynamics in multi-host and multi-parasite interaction system
Authors: Rabajante Jomar F. , Tubay Jerrold M. , Uehara Takashi , Morita Satoru , Ebert Dieter , Yoshimura Jin 
Published: April 2015

AbstractIn host-parasite systems, dominant host types are expected to be eventually replaced by other hosts due to the elevated potency of their specific parasites. This leads to changes in the abundance of both hosts and parasites exhibiting cycles of alternating dominance called Red Queen dynamics. Host-parasite models with less than three hosts and parasites have been demonstrated to exhibit Red Queen cycles, but natural host-parasite interactions typically involve many host and parasite types resulting in an intractable system with many parameters. Here we present numerical simulations of Red Queen dynamics with more than ten hosts and specialist parasites under the condition of no super-host nor super-parasite. The parameter region where the Red Queen cycles arise contracts as the number of interacting host and parasite types increases. The interplay between inter-host competition and parasite infectivity influences the condition for the Red Queen dynamics. Relatively large host carrying capacity and intermediate rates of parasite mortality result in never-ending cycles of dominant types.
Proteome-wide identification and quantification of S-glutathionylation targets in mouse liver
Authors: McGarry David J. , Chen Wenzhang , Chakravarty Probir , Lamont Douglas L. , Wolf C. Roland , Henderson Colin J. 
Published: April 2015

Protein S-glutathionylation is a reversible post-translational modification regulating sulfhydryl homeostasis. However, little is known about the proteins and pathways regulated by S-glutathionylation in whole organisms and current approaches lack the sensitivity to examine this modification under basal conditions. We now report the quantification and identification of S-glutathionylated proteins from animal tissue, using a highly sensitive methodology combining high-accuracy proteomics with tandem mass tagging to provide precise, extensive coverage of S-glutathionylated targets in mouse liver. Critically, we show significant enrichment of S-glutathionylated mitochondrial and Krebs cycle proteins, identifying that S-glutathionylation is heavily involved in energy metabolism processes in vivo. Furthermore, using mice nulled for GST Pi (GSTP) we address the potential for S-glutathionylation to be mediated enzymatically. The data demonstrate the impact of S-glutathionylation in cellular homeostasis, particularly in relation to energy regulation and is of significant interest for those wishing to examine S-glutathionylation in an animal model.
Full length and protease domain activity of chikungunya virus nsP2 differ from other alphavirus nsP2 proteases in recognition of small peptide substrates
Authors: Saisawang Chonticha , Sillapee Pornpan , Sinsirimongkol Kwanhathai , Ubol Sukathida , Smith Duncan R. , Ketterman Albert J. 
Published: April 2015

Alphavirus nsP2 proteins are multifunctional and essential for viral replication. The protease role of nsP2 is critical for virus replication as only the virus protease activity is used for processing of the viral non-structural polypeptide. Chikungunya virus is an emerging disease problem that is becoming a world-wide health issue. We have generated purified recombinant chikungunya virus nsP2 proteins, both full length and a truncated protease domain from the C-terminus of the nsP2 protein. Enzyme characterization shows that the protease domain alone has different properties compared with the full length nsP2 protease. We also show chikungunya nsP2 protease possesses different substrate specificity to the canonical alphavirus nsP2 polyprotein cleavage specificity. Moreover, the chikungunya nsP2 also appears to differ from other alphavirus nsP2 in its distinctive ability to recognize small peptide substrates.