bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Enantioselective Cyclopropanation of Enals by Oxidative N‐Heterocyclic Carbene Catalysis.
Authors: Biswas Anup , De Sarkar Suman , Tebben Ludger , Studer Armido 
Published: August 2012

Abstractα,β‐Unsaturated aldehydes are activated by a carbene‐catalyzed redox pathway to generate the corresponding acyl azolium intermediates, which react with sulfur ylides and an alcohol to give cyclopropanecarboxylic acid esters.
ChemInform Abstract: Development of Manganese(VI) Oxidizing Agents Soluble in Organic Solvents.
Authors: Ellis Rhys , Lee Kee‐Han , Ainsworth Matthew , Kerr Alexander , Viseux Eddy M. E. 
Published: August 2012

AbstractThe novel agent BAPM is prepared and successfully applied to the oxidation of alcohols, aniline, and 2‐aminothiophenol.
ChemInform Abstract: Oxidation of Alkyl Aromatics to Ketones by tert‐Butyl Hydroperoxide on Manganese Dioxide Catalyst.
Authors: Burange Anand S. , Kale Sandip R. , Jayaram Radha V. 
Published: August 2012

AbstractVarious cyclic systems containing active methylene sites are converted to ketones with a high level of selectivity under the optimized conditions A).
ChemInform Abstract: Dihydroxylation of Olefins Catalyzed by Zeolite‐Confined Osmium(0) Nanoclusters: An Efficient and Reusable Method for the Preparation of 1,2‐cis‐Diols.
Authors: Metin Oender , Alp Nurdan Alcan , Akbayrak Serdar , Bicer Abdullah , Gueltekin Mehmet Serdar , Oezkar Saim , Bozkaya Ugur 
Published: August 2012

AbstractA novel heterogeneous osmium catalyst is prepared and successfully applied for the dihydroxylation of different alkenes.
ChemInform Abstract: Development of Catalysts for the Stereoselective Hydrogenation of α,β‐Unsaturated Ketones.
Authors: Maurer Frauke , Huch Volker , Ullrich Angelika , Kazmaier Uli 
Published: August 2012

AbstractThe new iridium complex is found to be an efficient catalyst to produce various α‐substituted ketones with high enantioselectivity.
ChemInform Abstract: Suzuki—Miyaura Cross‐Coupling Reactions of Potassium Boc‐Protected Aminomethyltrifluoroborate with Aryl and Hetaryl Mesylates.
Authors: Molander Gary A. , Shin Inji 
Published: August 2012

AbstractThe title reaction allows an efficient access to a wide range of aminomethylarenes.
ChemInform Abstract: Regio‐ and Stereoselectivity in the Reactions of Organometallic Reagents with an Electron‐Deficient and an Electron‐Rich Vinyloxirane: Applications for Sequential Bis‐allylic Substitution Reactions in the Generation of Vicinal Stereogenic Centers.
Authors: Dieter R. Karl , Huang Yaxin , Guo Fenghai 
Published: August 2012

AbstractUnder appropriate conditions, the reaction of vinyloxiranes (I) and (IX) with organometallic reagents can take place with high regio‐ and stereoselectivity.
ChemInform Abstract: Preparation of Polystyrene‐Supported Lewis Acidic Fe(III) Ionic Liquid and Its Application in Catalytic Conversion of Carbon Dioxide.
Authors: Gao Jian , Song Qing‐Wen , He Liang‐Nian , Liu Chang , Yang Zhen‐Zhen , Han Xu , Li Xue‐Dong , Song Qing‐Chuan 
Published: August 2012

AbstractTerminal epoxides, aziridines, and a propargylic amine are efficiently carboxylated under neat conditions in the presence of the title catalyst to give cyclic carbonates and oxazolidinones, correspondingly.
ChemInform Abstract: Regioselective, Borinic Acid‐Catalyzed Monoacylation, Sulfonylation and Alkylation of Diols and Carbohydrates: Expansion of Substrate Scope and Mechanistic Studies.
Authors: Lee Doris , Williamson Caitlin L. , Chan Lina , Taylor Mark S. 
Published: August 2012

AbstractThe method can be generally applied to the monotosylation of pyranoside derivatives bearing three secondary hydroxyl groups.
ChemInform Abstract: Zinc Titanate Nanopowder: An Advanced Nanotechnology Based Recyclable Heterogeneous Catalyst for the One‐Pot Selective Synthesis of Self‐Aggregated Low‐Molecular Mass Acceptor—Donor—Acceptor—Acceptor Systems and Acceptor—Donor—Acceptor Triads.
Authors: Das Paramita , Butcher Ray J. , Mukhopadhyay Chhanda 
Published: August 2012

AbstractThe ZnTiO3‐catalyzed multicomponent reaction of ketones (I) with aldehydes (II) and malononitrile (III) under reflux leads to aromatic dinitriles (IV), whilst the reaction at room temperature affords trinitriles (V).
ChemInform Abstract: Iridium Catalyzed Enantioselective Hydrogenation of α‐Alkoxy and β‐Alkoxy Vinyl Ethers.
Authors: Zhu Ye , Burgess Kevin 
Published: August 2012

AbstractA variety of functionalized acid‐sensitive vinyl ethers is successfully hydrogenated in the presence of a chiral Ir—N‐carbene—oxazoline complex (ICOC).
ChemInform Abstract: A Highly Diastereoselective Decarboxylative Mannich Reaction of β‐Keto Acids with Optically Active N‐Sulfinyl α‐Imino Esters.
Authors: Yang Cui‐Feng , Shen Chen , Wang Jian‐Yong , Tian Shi‐Kai 
Published: August 2012

AbstractIt provides an efficient approach to optically active .gamma‐oxo‐α‐amino esters and acids.
ChemInform Abstract: Steric Tuning of C2‐Symmetric Chiral N‐Heterocyclic Carbene in Gold‐Catalyzed Asymmetric Cyclization of 1,6‐Enynes.
Authors: Yamada Ken‐ichi , Matsumoto Yasumasa , Selim Khalid B. , Yamamoto Yasutomo , Tomioka Kiyoshi 
Published: August 2012

AbstractEight chiral NHC‐gold(I) complexes are prepared and investigated.
ChemInform Abstract: Asymmetric α‐Oxyacylation of Cyclic Ketones.
Authors: Smithen Deborah A. , Mathews Christopher J. , Tomkinson Nicholas C. O. 
Published: August 2012

AbstractVarious N‐alkyl‐O‐acyl hydroxylamines are synthesized and their application to the title reaction with different cyclic ketones are investigated.
ChemInform Abstract: mpg‐C3N4 as a Solid Base Catalyst for Knoevenagel Condensations and Transesterification Reactions.
Authors: Su Fangzheng , Antonietti Markus , Wang Xinchen 
Published: August 2012

AbstractIn the Knoevenagel condensation of (I) with (IIa) the catalyst is recycled and used in five consecutive runs without loss of catalytic activity.
ChemInform Abstract: Mesoporous Nickel Hydroxyapatite Nanocomposition for Microwave‐Assisted Henry Reaction.
Authors: Neelakandeswari N. , Sangami G. , Emayavaramban P. , Karvembu R. , Dharmaraj N. , Kim Hak Yong 
Published: August 2012

AbstractThe catalyst is prepared and used for the title reaction of aromatic aldehydes with nitromethane.
ChemInform Abstract: Synthesis of Acridines and Persubstituted Phenols from Cyclobutenones and Active Methylene Ketones.
Authors: Han Xiao‐Dan , Zhao Yu‐Long , Meng Jia , Ren Chuan‐Qing , Liu Qun 
Published: August 2012

AbstractBase‐mediated treatment of cyclobutenones with active methylene ketones provides a new and regioselective approach to persubstituted phenols.
ChemInform Abstract: Simple Preparation of β‐Amino Alcohols Possessing a tert‐Butyl Group at the α‐Carbon.
Authors: Zacharia James T. , Tanaka Takanori , Uesaka Yumiko , Hayashi Masahiko 
Published: August 2012

AbstractAmong the title compounds, derivatives (Ic) and (Id) which bear the tert‐butyl group at the α‐carbon, are shown to be efficient catalysts for the asymmetric addition of diethylzinc to benzaldehyde.
ChemInform Abstract: A Biocatalytic Approach for Regioselective Monoacetylation of 3‐Aryloxy‐1,2‐propanediols by Porcine Pancreatic Lipase.
Authors: Meena Vachan Singh , Banerjee U. C. 
Published: August 2012

AbstractOptimized reaction conditions are examined for the lipase‐catalyzed regioselective monoacetylation of 3‐aryloxy‐1,2‐propanediols (I).
ChemInform Abstract: Enantioselective Organocatalytic Michael Addition of 2‐Arylacetates and 2‐Arylacetonitriles Having an Electron‐Withdrawing Group to α,β‐Unsaturated Aldehydes.
Authors: Seo Seung Woo , Kim Sung‐Gon 
Published: August 2012

AbstractOptimized conditions render possible the preparation of various target compounds whose functionalities allow transformation to biologically important substances.
ChemInform Abstract: Sulfuric Acid Catalyzed Addition of β‐Dicarbonyl Compounds to Alcohols under Conventional Heating and Microwave‐Assisted Conditions.
Authors: Xia Fei , Zhao Zheng Le , Liu Pei Nian 
Published: August 2012

AbstractThe investigation of a broad spectrum reveals that there is no advantage of a microwave version compared to conventional conditions.
ChemInform Abstract: Ruthenium(II) Carbonyl Complexes Containing Benzhydrazone Ligands: Synthesis, Structure and Facile One‐Pot Conversion of Aldehydes to Amides.
Authors: Prabhu Rupesh Narayana , Ramesh Rengan 
Published: August 2012

AbstractA newly developed catalyst is successfully applied to the synthesis of the title amides (II).
ChemInform Abstract: Copper‐Catalyzed Cyanation of Benzyl Chlorides with Non‐Toxic K4[Fe(CN)6].
Authors: Ren Yunlai , Dong Chuanhua , Zhao Shuang , Sun Yanpei , Wang Jianji , Ma Junying , Hou Chaodong 
Published: August 2012

AbstractThe method avoids the use of a non‐toxic cyanide source and metal catalysis.
ChemInform Abstract: Palladium Nanoparticles Supported on Silicadiphenyl Phosphinite (SDPP) as Efficient Catalyst for Mizoroki—Heck and Suzuki—Miyaura Coupling Reactions.
Authors: Iranpoor Nasser , Firouzabadi Habib , Motevalli Somayeh , Talebi Mohsen 
Published: August 2012

AbstractA cheap and convenient method for the phosphorylation of silica gel is developed and the material is used to immobilize Pd(0)‐nanoparticles.
ChemInform Abstract: A Highly Efficient Catalyst‐Free Protocol for C—H Bond Activation: Sulfamidation of Alkyl Aromatics and Aldehydes.
Authors: Borah Arun Jyoti , Phukan Prodeep 
Published: August 2012

AbstractAmination of toluene derivatives with the compound (II) fails in Et‐O‐Ac, while the reaction takes place under solvent‐free conditions [cf.
ChemInform Abstract: A One‐Pot Regioselective Synthetic Route to Vinyl Sulfones from Terminal Epoxides in Aqueous Media.
Authors: Chawla Ruchi , Kapoor Ritu , Singh Atul K. , Yadav Lal Dhar S. 
Published: August 2012

AbstractThe reaction of 2‐alkylepoxides with sulfinates (II) leads selectively to sulfones (IV), whilst the analogous reaction of 2‐arylepoxides affords a mixture of two regioisomers (III) and (IV).
ChemInform Abstract: An Efficient Synthesis of a Potent Antiinflammatory Agent, Viscolin, and Its Inducible Nitric Oxide Synthase Inhibitory Activity.
Authors: Kuo Ping‐Chung , Chen Yi‐Hsien , Leu Yann‐Lii , Huang Chieh‐Hung , Liao Yu‐Ren , Lee E‐Jian , Yang Mei‐Lin , Wu Tian‐Shung 
Published: August 2012

AbstractA more efficient procedure for the large‐scale production of viscolin (VIII) is presented.
ChemInform Abstract: One‐Pot Synthesis of Unsymmetrical Benzils from Aryl Methyl Ketones and Arenes in the Presence of Selenous Acid Catalyzed by p‐Toluenesulfonic Acid Monohydrate.
Authors: Kharkongor Icydora , Rohman Md. Rumum , Myrboh Bekington 
Published: August 2012

AbstractA modified process is presented for the oxidative coupling of acetophenones with weakly or unactivated arenes to produce the synthetically important benzil structures.
ChemInform Abstract: Iodine Mediated/Broensted Acid‐Catalyzed Dimerization of Vinylarenes: A Tandem Reaction Through Ritter Trapping to Produce N‐(4‐Iodo‐1,3‐diarylbutyl) Acetamides.
Authors: Huang Jing‐Mei , Ye Zhi‐Jun , Chen Dong‐Song , Zhu Hong 
Published: August 2012

AbstractThe new title one‐step reaction is developed by using readily available starting materials.
ChemInform Abstract: Design, Synthesis, and Biological Evaluation of Bromophenol Derivatives as Protein Tyrosine Phosphatase 1B Inhibitors.
Authors: Jiang Bo , Shi Dayong , Cui Yongchao , Guo Shuju 
Published: August 2012

AbstractA variety of bromophenol derivatives with bicyclic, tricyclic or tetracyclic scaffold is synthesized and evaluated for protein tyrosine phosphatase 1B inhibitory activity.
ChemInform Abstract: Simple and Inexpensive Threonine‐Based Organocatalysts as Highly Active and Recoverable Catalysts for Large‐Scale Asymmetric Direct Stoichiometric Aldol Reactions on Water.
Authors: Wu Chuanlong , Long Xiaoqin , Li Shi , Fu Xiangkai 
Published: August 2012

AbstractA newly designed catalyst is successfully applied to the title reaction which can be performed on a large‐scale under these conditions.
ChemInform Abstract: C2‐Symmetric Proline‐Derived Tetraamine as Highly Effective Catalyst for Direct Asymmetric Michael Addition of Ketones to Chalcones.
Authors: Ma Shijun , Wu Lulu , Liu Ming , Wang Yongmei 
Published: August 2012

AbstractFor the first time this type of catalyst is effectively applied to the title addition reaction under mild conditions.
ChemInform Abstract: Synthesis of Unsymmetrically Substituted 2,2′‐Dihydroxy‐1,1′‐biaryl Derivatives Using Organic‐Base‐Catalyzed Ferrier‐Type Rearrangement as the Key Step.
Authors: Terada Masahiro , Dan Katsunori 
Published: August 2012

AbstractAn enantioselective reaction in the presence of a chiral base leads to low yields and e.e.
ChemInform Abstract: Conformationally Restricted Naphthalene Derivatives Type isoCombretastatin A‐4 and isoErianin Analogues: Synthesis, Cytotoxicity and Antitubulin Activity.
Authors: Provot Olivier , et al. et al. 
Published: August 2012

AbstractThree new classes of inhibitors of tubulin polymerization, based on the skeleton of dihydronapthalenes, tetrahydronapthalenes, and naphthalenes, are synthesized by a convergent strategy.
ChemInform Abstract: Light‐Induced Carbocyclization of Iodoalkenes.
Authors: Campos‐Gomez Esther , Campos Pedro J. , Gonzalez Hector F. , Rodriguez Miguel A. 
Published: August 2012

AbstractThe direct irradiation of iodoalkenes leads to homolysis of the C—I bond followed by cyclization with formation of 6‐membered.
ChemInform Abstract: Organocatalytic Stereocontrolled Synthesis of 3,3′‐Pyrrolidinyl Spirooxindoles by [3 + 2] Annulation of Isocyanoesters with Methyleneindolinones.
Authors: Wang Liang‐Liang , Bai Jian‐Fei , Peng Lin , Qi Liang‐Wen , Jia Li‐Na , Guo Yun‐Long , Luo Xi‐Ya , Xu Xiao‐Ying , Wang Li‐Xin 
Published: August 2012

AbstractThe annulation proceeds with anti‐ or syn‐stereoselectivity depending on the N‐protecting group of starting oxindoles.
ChemInform Abstract: Passerini Reactions for the Efficient Synthesis of 3,3‐Disubstituted Oxetanes.
Authors: Beasley Banjamin O. , Clarkson Guy J. , Shipman Michael 
Published: August 2012

AbstractThe reaction of unsubstituted oxetan‐3‐one (I) with isocyanides and carboxylic acids allows the access to various pharmaceutically interesting products of type (IV).
ChemInform Abstract: Formal [4 + 1] Annulation of Cyclopropyl Amides and Water Mediated by Lewis Acid: A Novel Entry to γ‐Butyrolactones.
Authors: Zhang Dingyuan , Zhang Rui , Liang Yongju , Dong Dewen 
Published: August 2012

AbstractA ring‐opening/recyclization process of readily available cyclopropylamides (I) is efficiently achieved with the Lewis acid SnCl4 to offer a novel synthesis of γ‐butyrolactones (II).
ChemInform Abstract: Ruthenium‐Catalyzed Transfer Oxygenative Cyclization of α,ω‐Diynes: Unprecedented [2 + 2 + 1] Route to Bicyclic Furans via Ruthenacyclopentatriene.
Authors: Yamashita Ken , Yamamoto Yoshihiko , Nishiyama Hisao 
Published: August 2012

AbstractGenerally, a broad spectrum of bicyclic furan skeletons can be obtained from diynes bearing 2 terminal aryl substituents under the optimized conditions A)‐C).
ChemInform Abstract: Catalytic Enantioselective Construction of Quaternary Stereocenters by Direct Vinylogous Michael Addition of Deconjugated Butenolides to Nitroolefins.
Authors: Manna Madhu Sudan , Kumar Vikas , Mukherjee Santanu 
Published: August 2012

AbstractThe title reaction provides access to highly functionalized γ‐butenolides bearing contiguous quaternary and tertiary stereocenters with high to excellent diastereo‐ and enantioselectivities.
ChemInform Abstract: Regiospecific Synthesis of Cepanolide, a Cancer Chemoprotective Micronutrient Found in Green Onions.
Authors: Boukouvalas John , Albert Vincent 
Published: August 2012

AbstractOn treatment with thiols, the brominated hydroxybutenolide (II) can be regioselectively converted to cepanolide (IVa) and some analogues.
ChemInform Abstract: New Fluoride‐Promoted Hypoiodite‐Catalytic Oxidative Cycloetherification to Aromatic Spiroketals.
Authors: Wei Wei , Li Liqi , Lin Xiaohong , Li Haifeng , Xue Jijun , Li Ying 
Published: August 2012

AbstractHypoiodide reagents, generated in situ from Bu4NI, catalyze the synthesis of bisbenzannulated spiroketal cores.
ChemInform Abstract: CN‐Assisted Oxidative Cyclization of Cyano Cinnamates and Styrene Derivatives: A Facile Entry to 3‐Substituted Chiral Phthalides.
Authors: Reddy R. Santhosh , Kiran I. N. Chaithanya , Sudalai Arumugam 
Published: August 2012

AbstractA novel, highly practical, and efficient approach to the title compounds is developed.
ChemInform Abstract: Palladium‐Based Catalytic System for the Direct C3‐Arylation of Furan‐2‐carboxamides and Thiophene‐2‐carboxamides.
Authors: Si Larbi Karima , Fu Hai Yan , Laidaoui Nouria , Beydoun Kassem , Miloudi Abdellah , El Abed Douniazad , Djabbar Safia , Doucet Henri 
Published: August 2012

AbstractThe Pd‐catalyzed direct arylation of title furan‐ and thiophenecarboxamides proceeds regioselectively at position C‐3 when the system Cs2CO3—xylene is applied.
ChemInform Abstract: Gold(I)‐Catalyzed Rearrangement of 3‐Silyloxy‐1,5‐enynes: An Efficient Synthesis of Benzo[b]thiophenes, Dibenzothiophenes, Dibenzofurans, and Indole Derivatives.
Authors: Hashmi A. Stephen K. , Yang Weibo , Rominger Frank 
Published: August 2012

AbstractBenzanellated heterocycles are efficiently synthesized by the present new tandem 5‐endo‐dig cyclization/2,3‐shift procedure.
ChemInform Abstract: A New Three‐Component Reaction Catalyzed by Silica Sulfuric Acid: Synthesis of Tetrasubstituted Pyrroles.
Authors: Tamaddon Fatemeh , Farahi Mahnaz 
Published: August 2012

AbstractA novel convenient method is presented for the reaction of benzoin derivatives with 1,3‐dicarbonyl compounds and ammonium acetate.
ChemInform Abstract: Domino Cyclization—Alkylation Protocol for the Synthesis of 2,3‐Functionalized Indoles from o‐Alkynylanilines and Allylic Alcohols.
Authors: Xu Chang , Murugan Vinod K. , Pullarkat Sumod A. 
Published: August 2012

AbstractA practical, mild, clean, atom‐economical and efficient protocol for the one‐pot synthesis of the title compounds is developed without the use of any additives.
ChemInform Abstract: Asymmetric N‐Allylation of Indoles Through the Iridium‐Catalyzed Allylic Alkylation/Oxidation of Indolines.
Authors: Liu Wen‐Bo , Zhang Xiao , Dai Li‐Xin , You Shu‐Li 
Published: August 2012

AbstractA wide range of enantioenriched N‐allylindoles is synthesized by the two‐step procedure.
ChemInform Abstract: Organocatalytic Asymmetric Conjugate Addition of 3‐Monosubstituted Oxindoles to (E)‐1,4‐Diaryl‐2‐buten‐1,4‐diones: A Strategy for the Indirect Enantioselective Furanylation and Pyrrolylation of 3‐Alkyloxindoles.
Authors: Liao Yu‐Hua , Liu Xiong‐Li , Wu Zhi‐Jun , Du Xi‐Lin , Zhang Xiao‐Mei , Yuan Wei‐Cheng 
Published: August 2012

AbstractThe disubstituted oxindoles containing a 1,4‐dicarbonyl moiety are subsequently cyclized either into 3‐furanyl‐ or 3‐pyrrolyl‐oxindoles which are difficult to obtain by other methods.
ChemInform Abstract: Ruthenium‐Catalyzed Intramolecular Cyclization of Diaza‐β‐ketoanilides for the Synthesis of 3‐Alkylideneoxindoles.
Authors: Chan Wai‐Wing , Kwong Tsz‐Lung , Yu Wing‐Yiu 
Published: August 2012

AbstractAn excellent chemoselective and mild synthesis of the title compounds from easy to handle starting materials is developed.
ChemInform Abstract: Expedient Synthesis of 1‐Hydroxy‐4‐ and 1‐Hydroxy‐6‐nitroindoles.
Authors: Bujok Robert , Wrobel Zbigniew , Wojciechowski Krzysztof 
Published: August 2012

AbstractNucleophilic substitution of hydrogen in 1,3‐dinitrobenzene (I) or acylation of dinitrotoluenes (VI) gives dinitrobenzoyl ketones which undergo reductive cyclization to produce the 1‐hydroxyindole derivatives.
ChemInform Abstract: Bicyclic Guanidine Catalyzed Asymmetric Michael Additions of 3‐Benzyl‐Substituted Oxindoles to N‐Maleimides.
Authors: Li Lixin , Chen Wenchao , Yang Wenguo , Pan Yuanhang , Liu Hongjun , Tan Choon‐Hong , Jiang Zhiyong 
Published: August 2012

AbstractThe described approach is the first report on the stereospecific embedment of N‐benzylic α‐branched succinimides into the framework of 3,3‐disubstituted oxindoles.
ChemInform Abstract: nBu4NI‐Catalyzed C3‐Formylation of Indoles with N‐Methylaniline.
Authors: Li Lan‐Tao , Huang Juan , Li Hong‐Ying , Wen Li‐Juan , Wang Peng , Wang Bin 
Published: August 2012

AbstractRegioselective formylation of NH‐ and N‐protected indoles is smoothly achieved with N‐methylaniline in the presence of TBAI catalyst and tert‐butyl perbenzoate as oxidant.
ChemInform Abstract: An Efficient Synthesis of N‐Substituted Indoles from Indoline/Indoline Carboxylic Acid via Aromatization Followed by C—N Cross‐Coupling Reaction by Using Nano Copper Oxide as a Recyclable Catalyst.
Authors: Reddy K. Harsha Vardhan , Satish G. , Ramesh K. , Karnakar K. , Nageswar Y. V. D. 
Published: August 2012

AbstractIodides are generally more efficient than other halides.
ChemInform Abstract: Condensation of Propargylic Alcohols with Indoles and Carbazoles in [bmim][PF6] /Bi(NO3)3·5H2O: A Simple High‐Yielding Propargylation Method with Recycling and Reuse of the Ionic Liquid.
Authors: Kumar G. G. K. S. Narayana , Aridoss Gopalakrishnan , Laali Kenneth K. 
Published: August 2012

AbstractThe title method allows the regioselective synthesis of functionalized heterocyclic systems.
ChemInform Abstract: Synthesis of Novel Spirooxindole Derivatives by One Pot Multicomponent Reaction and Their Antimicrobial Activity.
Authors: Bhaskar Gangaru , Arun Yuvaraj , Balachandran Chandrasekar , Saikumar Chandrasekara , Perumal Paramasivan T. 
Published: August 2012

Abstract1,3‐Dipolar cycloaddition of azomethine ylides, generated in situ via decarboxylative condensation of isatins (I) and (IX) and sarcosine (II) or (L)‐proline (X), to naphthoquinone (III), followed by spontaneous dehydrogenation afford the spirooxindoles (IV) and (XI), resp., in high yields.
ChemInform Abstract: Synthesis of Enantiopure 5‐Substituted 2,3‐Methanopyrrolidines by Cyclization of Enantiopure α‐Branched α‐N‐Homoallylamino Nitriles.
Authors: Ouizem Sabrina , Chemla Fabrice , Ferreira Franck , Perez‐Luna Alejandro 
Published: August 2012

AbstractThe transformation to the biologically important scaffolds proceeds with high diastereoselectivity and enantioselectivity only for a few selected substrates.
ChemInform Abstract: Highly Efficient and Chemoselective Method for the Thioacetalization of Aldehydes and Transthioacetalization of Acetals and Acylals Catalyzed by H2SO4‐Silica under Solvent‐Free Conditions.
Authors: Pourmousavi Seied Ali , Kazemi Shaghayegh Sadat 
Published: August 2012

AbstractThioacetalization of a variety of aldehydes can be performed with 1,2‐ethanedithiol (II) using H2SO4‐silica under solvent‐free conditions.
ChemInform Abstract: Conformationally Restricted Novel Pyrazole Derivatives: Synthesis of 1,8‐Disubstituted 5,5‐Dimethyl‐4,5‐dihydro‐1H‐benzo[g]indazoles as a New Class of PDE4 Inhibitors.
Authors: Venkataiah S. , et al. et al. 
Published: August 2012

AbstractNew indazoles (IVa)—(IVd) show promising PDE4B inhibitory properties in vitro and good interactions with PDE4B in silico.
ChemInform Abstract: Novel Diversely Substituted 1‐Heteroaryl‐2‐imidazolines for Fragment‐Based Drug Discovery.
Authors: Krasavin Mikhail 
Published: August 2012

AbstractThe synthesis of the title compounds (V) (20 examples) is based on a Pd‐catalyzed Buchwald—Hartwig N‐heteroarylation of 2‐imidazolines with hetaryl halides.
ChemInform Abstract: 2‐Aminobenzimidazole Derivatives Strongly Inhibit and Disperse Pseudomonas aeruginosa Biofilms.
Authors: Frei Reto , Breitbach Anthony S. , Blackwell Helen E. 
Published: August 2012

AbstractA small library of 2‐aminobenzimidazole derivatives (III)/(IV) is synthesized to probe their capability of inhibiting growth and dispersing Pseudomonas aeruginosa biofilms.