bluuebunny/crossref_metadata_2025_split huggingface dataset:
In vitro bioactivity and degradability of β‐tricalcium phosphate porous scaffold fabricated via selective laser sintering
Authors: Shuai Cijun , Zhuang Jingyu , Hu Huanlong , Peng Shuping , Liu Defu , Liu Jinglin 
Published: April 2013

AbstractPorous scaffolds consisting of β‐tricalcium phosphate (β‐TCP) were successfully fabricated via selective laser sintering. The scaffolds had a controlled microstructure and totally interconnected porous structure. The microstructure and mechanical properties were studied. The bioactivity and degradability of scaffolds were evaluated through the simulated body fluid (SBF) cultivation experiment. The formation of a biologically active carbonate apatite layer on the surface after immersion in SBF was demonstrated using scanning electron microscope, energy dispersive X‐ray, and Fourier transform infrared spectroscopy. Fast nucleation and growth of the carbonate apatite crystals were observed to occur all through the specimen surfaces. The phenomenon was explained in terms of the distribution and dispersion of inorganic phases in the scaffolds and the ionic activity products of the apatite in the SBF. The calculation results of weight loss and Ca/P molar ratio also suggest the good bioactivity and degradability of the scaffolds. These indicate that the β‐TCP porous ceramic scaffold is a potential candidate scaffold for bone tissue engineering.
PfaH2: A novel hydrophobin from the ascomycete Paecilomyces farinosus
Authors: Zelena Katerina , Takenberg Meike , Lunkenbein Stefan , Woche Susanne K. , Nimtz Manfred , Berger Ralf G. 
Published: April 2013

AbstractThe pfah2 gene coding for a novel hydrophobin PfaH2 from the ascomycete Paecilomyces farinosus was identified during sequencing of random clones from a cDNA library. The corresponding protein sequence of PfaH2 deduced from the cDNA comprised 134 amino acids (aa). A 16 aa signal sequence preceded the N‐terminus of the mature protein. PfaH2 belonged to the class Ia hydrophobins. The protein was isolated using trifluoroacetic acid extraction and purified via SDS‐PAGE and high‐performance liquid chromatography. The surface activity of the recently described PfaH1 and of PfaH2 was compared by the determination of contact angles (CAs) on glass slides and Teflon tape, and the CA of distilled water droplets was measured on glass slides coated with hydrophobin PfaH1 or PfaH2. Surprisingly, both hydrophobins adsorbed to hydrophilic surfaces and changed their physicochemical properties to a similar quantitative extent, although little aa sequence homology was found.
An integrated two‐stage anaerobic digestion and biofuel production process to reduce life cycle GHG emissions from US dairies
Authors: Coats Erik R. , Searcy Erin , Feris Kevin , Shrestha Dev , McDonald Armando G. , Briones Aurelio , Magnuson Timothy , Prior Maxine 
Published: April 2013

AbstractOver 9 million dairy cows generate an estimated 226 billion kg of wet manure annually in the USA. To help mitigate dairy greenhouse gas (GHG) emissions associated with the degradation of this organic‐rich waste, manure can be processed via anaerobic digestion (AD) to methane and ultimately electricity. This potential value of AD has generated high‐level dairy‐industry support for broad‐scale technology deployment; however, on‐the‐ground AD realization has been impeded by process stability/reliability concerns and poor economics. Considering these challenges but recognizing that AD represents a fundamentally sound manure‐management approach, an interdisciplinary research team has completed proof‐of‐concept investigations on an integrated process that will concurrently improve manure management economics and reduce dairy GHG emissions. The integrated processes center on a two‐stage fermentation/AD system that can generate methane quantity/quality comparable to conventional single‐stage AD. Molecular level investigations confirm that the AD is highly enriched with a unique and synergistic microbial population which yielded a more resilient and stable process. Beyond AD, algae grown on nitrogen/phosphorus‐rich AD supernatant in a photobioreactor yielded biomass concentrations approaching 1.0 g L–1; despite an apparent growth lag/inhibition associated with excess organic acids and ammonia, algae growth was significant. Environmental life cycle assessment (LCA) demonstrated that the two‐stage AD configuration coupled with algae production can reduce GHG emissions by approximately 60% as compared with a traditional anaerobic lagoon. The end result is a manure‐management platform that can increase US dairy viability and sustainability. Ongoing investigations are aimed at process refinement with an ultimate commercialization goal. © 2013 Society of Chemical Industry and John Wiley & Sons, Ltd
Breast cancer molecular subtypes and survival in a hospital‐based sample in Puerto Rico
Authors: Ortiz Ana Patricia , Frías Orquidea , Pérez Javier , Cabanillas Fernando , Martínez Lisa , Sánchez Carola , Capó‐Ramos David E. , González‐Keelan Carmen , Mora Edna , Suárez Erick 
Published: April 2013

AbstractInformation on the impact of hormone receptor status subtypes in breast cancer (BC) prognosis is still limited for Hispanics. We aimed to evaluate the association of BC molecular subtypes and other clinical factors with survival in a hospital‐based female population of BC cases in Puerto Rico. We analyzed 663 cases of invasive BC diagnosed between 2002 and 2005. Information on HER‐2/neu (HER‐2) overexpression, estrogen (ER), and progesterone (PR) receptor status and clinical characteristics were retrieved from hospitals cancer registries and record review. Survival probabilities by covariates of interest were described using the Kaplan–Meier estimators. Cox proportional hazards models were employed to assess factors associated with risk of BC death. Overall, 17.3% of BC cases were triple‐negative (TN), 61.8% were Luminal‐A, 13.3% were Luminal‐B, and 7.5% were HER‐2 overexpressed. In the multivariate Cox model, among patients with localized stage, women with TN BC had higher risk of death (adjusted hazard ratio [HR]: 2.57, 95% confidence interval [CI]: 1.29–5.12) as compared to those with Luminal‐A status, after adjusting for age at diagnosis. In addition, among women with regional/distant stage at diagnosis, those with TN BC (HR: 5.48, 95% CI: 2.63–11.47) and those HER‐2+, including HER‐2 overexpressed and Luminal‐B, (HR: 2.73, 95% CI:1.30–5.75) had a higher mortality. This is the most comprehensive epidemiological study to date on the impact of hormone receptor expression subtypes in BC survival in Puerto Rico. Consistent to results in other populations, the TN subtype and HER‐2+ tumors were associated with decreased survival.
The Structure of Glycerol Trinitrate Reductase NerA from Agrobacterium radiobacter Reveals the Molecular Reason for Nitro‐ and Ene‐Reductase Activity in OYE Homologues
Authors: Oberdorfer Gustav , Binter Alexandra , Wallner Silvia , Durchschein Katharina , Hall Mélanie , Faber Kurt , Macheroux Peter , Gruber Karl 
Published: April 2013

AbstractIn recent years, Old Yellow Enzymes (OYEs) and their homologues have found broad application in the efficient asymmetric hydrogenation of activated CC bonds with high selectivities and yields. Members of this class of enzymes have been found in many different organisms and are rather diverse on the sequence level, with pairwise identities as low as 20 %, but they exhibit significant structural similarities with the adoption of a conserved (αβ)8‐barrel fold. Some OYEs have been shown not only to reduce CC double bonds, but also to be capable of reducing nitro groups in both saturated and unsaturated substrates. In order to understand this dual activity we determined and analyzed X‐ray crystal structures of NerA from Agrobacterium radiobacter, both in its apo form and in complex with 4‐hydroxybenzaldehyde and with 1‐nitro‐2‐phenylpropene. These structures, together with spectroscopic studies of substrate binding to several OYEs, indicate that nitro‐containing substrates can bind to OYEs in different binding modes, one of which leads to CC double bond reduction and the other to nitro group reduction.
Materials‐Based Receptors: Design Principle and Applications
Authors: Singh Kamaljit , Sareen Divya , Kaur Paramjit , Miyake Hiroyuki , Tsukube Hiroshi 
Published: April 2013

AbstractThis review focuses on recent developments and growth potential in colorimetric and/or fluorimetric chemosensors based on rationally designed materials and suitable for use in highly selective and sensitive naked‐eye detection of environmental and biological analytes.
ChemInform Abstract: Synthesis, Crystal Structure and Chemical Bonding of RE5‐xLixGe4 (RE: Nd, Sm and Gd; x ≅ 1) with the Orthorhombic Gd5Si4 Type.
Authors: Suen Nian‐Tzu , You Tae‐Soo , Bobev Svilen 
Published: April 2013

AbstractThe compounds Sm3.97Li1.03Ge4, Nd3.97Li1.03Ge4, and Gd3.96Li1.03Ge4 are synthesized by solid state reactions of stoichiometric mixtures of the elements (sealed Nb container in an evacuated silica tube, 1358 K, 5 h).
ChemInform Abstract: Growth, Crystal Structure and Optical Properties of a New Layered Fluorine Beryllium Borate, Sr0.23Ca0.77Na2Be2B2 O6F2.
Authors: Huang Hongwei , Yao Wenjiao , Wang Xiaoyang , Zhai Naixia , Chen Chuangtian 
Published: April 2013

AbstractThe title fluorine beryllium borate crystal is grown by high temperature solid state reaction of CaCO3, SrCO3, BeO, B2O3, and NaF in stoichiometric amounts (710°C, 48 h).
ChemInform Abstract: Antiferromagnetic Ordering in an Intermediate Valence Compound Ce9Ru4Ga5.
Authors: Kaczorowski Dariusz , Murashova Elena , Kurenbaeva Zhanaphia 
Published: April 2013

AbstractThe novel Ce9Ru4Ga5 is prepared by arc melting and shows an unusually short Ce—Ru distance in its structure.
ChemInform Abstract: Structural, Magnetic and Transport Study of Monovalent Na‐Doped Manganite Pr0.55Na0.05Sr0.4MnO3.
Authors: Thaljaoui R. , Boujelben W. , Pekala M. , Pekala K. , Mucha J. , Cheikhrouhou A. 
Published: April 2013

AbstractThe manganite Pr0.55Na0.05Sr0.4MnO3 is prepared by standard solid state reaction.
ChemInform Abstract: Organocatalytic, Highly Enantioselective Vinylogous Mukaiyama—Michael Reaction of Acyclic Dienol Silyl Ethers.
Authors: Gupta Vaishali , Sudhir V. Sai , Mandal Tanmay , Schneider Christoph 
Published: April 2013

AbstractThis reaction is accomplished for the first time.
ChemInform Abstract: Hypervalent Iodine Catalyzed Hofmann Rearrangement of Carboxamides Using Oxone as Terminal Oxidant.
Authors: Yoshimura Akira , Middleton Kyle R. , Luedtke Matthew W. , Zhu Chenjie , Zhdankin Viktor V. 
Published: April 2013

AbstractThe reaction is proposed to proceed via electron‐deficient active species generated from hydroxy(phenyl)iodonium ion or hypervalent aminoiodane and (F3C)2CH—OH.
ChemInform Abstract: Catalytic Enantioselective α‐Tosyloxylation of Ketones Using Iodoaryloxazoline Catalysts: Insights on the Stereoinduction Process.
Authors: Guilbault Audrey‐Anne , Basdevant Benoit , Wanie Vincent , Legault Claude Y. 
Published: April 2013

AbstractAn unprecedented mode of stereoinduction from chiral oxazolines is discovered, with the stereogenic center alpha to the oxazolines oxygen atom being significant.
ChemInform Abstract: Trifluoromethylation of Alkenes by Visible Light Photoredox Catalysis.
Authors: Iqbal Naeem , Choi Sungkyu , Kim Eunjin , Cho Eun Jin 
Published: April 2013

AbstractThis radical‐based trifluoromethylation of unactivated alkenes shows broad substrate scope and high E‐selectivity.
ChemInform Abstract: Iridium‐Catalyzed Allylation of Chiral β‐Stereogenic Alcohols: Bypassing Discrete Formation of Epimerizable Aldehydes.
Authors: Schmitt Daniel C. , Dechert‐Schmitt Anne‐Marie R. , Krische Michael J. 
Published: April 2013

AbstractLigand IRC in its (S) or (R) form is found to be optimal for the direct C—H allylation of β‐substituted chiral primary alcohols.
ChemInform Abstract: Novel Skeleton Transformation Reaction of α‐Pyrone Derivatives to Spirobicyclo[3.1.0]hexane Derivatives Using Dimethylsulfoxonium Methylide.
Authors: Miura Takuya , Yadav Navnath Dnyanoba , Iwasaki Hiroki , Ozeki Minoru , Kojima Naoto , Yamashita Masayuki 
Published: April 2013

AbstractIn situ generated dimethylsulfoxonium methylide is used to synthesize the title compounds in moderate yields.
ChemInform Abstract: Iridium‐Catalyzed Asymmetric Hydrogenation of α‐Substituted α,β‐Unsaturated Acyclic Ketones: Enantioselective Total Synthesis of (—)‐Mesembrine.
Authors: Zhang Qian‐Qian , Xie Jian‐Hua , Yang Xiao‐Hui , Xie Jian‐Bo , Zhou Qi‐Lin 
Published: April 2013

AbstractThe spiro pyridine‐aminophosphine catalyst ligands (I) are successfully applied in the title reaction to afford the alcohol products with excellent enantioselectivity.
ChemInform Abstract: A New Catalyst for the Asymmetric Henry Reaction: Synthesis of β‐Nitroethanols in High Enantiomeric Excess.
Authors: White James D. , Shaw Subrata 
Published: April 2013

AbstractThe catalyst system including ligand (I) is successfully applied to the reaction of a broad spectrum of aldehydes with nitromethane and can be extended to a diastereoselective preparation of analogues (XIII) in the presence of nitropropane.
ChemInform Abstract: Tris(4‐methoxyphenyl)phosphine‐Catalyzed C—C Bond Formation Reaction: Mutual Addition of Aromatic Aldehydes and Ethyl Acrylate.
Authors: Teng Jun‐Jiang , Qiao Yan‐Hui , Zhang Qing , Li Chun‐Hai , Huang Min 
Published: April 2013

AbstractAn efficient and rapid access to various 1,4‐dicarbonyl compounds and allylic alcohol derivatives from readily available starting materials under mild reaction conditions is presented.
ChemInform Abstract: Au(III)‐Catalyzed Intermolecular Amidation of Benzylic C—H Bonds.
Authors: Zhang Yan , Feng Bainian , Zhu Chengjian 
Published: April 2013

AbstractNovel and highly efficient Au‐catalyzed amidations of benzylic C—H bonds with sulfonamides and carboamides are described.
ChemInform Abstract: Palladium/Norbornene Catalysis: A Versatile Aryl C—H Hydroxyalkylation, Alkyl Cinnamate Formation.
Authors: Jafarpour Farnaz , Jalalimanesh Nafiseh 
Published: April 2013

AbstractAcrylates and aliphatic alcohols are appropriate reagents in palladium‐catalyzed, norbornene‐mediated domino ortho‐alkylation/Heck reactions.
ChemInform Abstract: A Simple Metal‐Free Catalytic Sulfoxidation under Visible Light and Air.
Authors: Gu Xiangyong , Li Xiang , Chai Yahong , Yang Qi , Li Pixu , Yao Yingming 
Published: April 2013

AbstractA metal‐free aerobic selective sulfoxidation photosensitized by Rose Bengal or solid‐supported Rose Bengal is developed.
ChemInform Abstract: Chugaev‐Type Bis(acyclic diaminocarbenes) as a New Ligand Class for the Palladium‐Catalyzed Mizoroki—Heck Reaction.
Authors: Owusu Millicent O. , Handa Sachin , Slaughter LeGrande M. 
Published: April 2013

AbstractThe structurally optimized catalyst is successfully applied to the title reaction.
ChemInform Abstract: Efficient Diels—Alder Reaction of 1,2‐Benzoquinones with Arynes and Its Utility in One‐Pot Reactions.
Authors: Kaicharla Trinadh , Bhojgude Sachin Suresh , Biju Akkattu T. 
Published: April 2013

AbstractThe arynes react with 1,2‐benzoquinones to give dioxobenzobicyclooctadienes.
ChemInform Abstract: Enantioselective Iodolactonization of Disubstituted Olefinic Acids Using a Bifunctional Catalyst.
Authors: Fang Chao , Paull Daniel H. , Hethcox J. Caleb , Shugrue Christopher R. , Martin Stephen F. 
Published: April 2013

AbstractA bifunctional BINAP‐derived amidine is shown to be highly efficient for the process.
ChemInform Abstract: Expeditious Synthesis of the Cores of Naturally Occurring Cyclic Polyethers Using a Divergent Ring Rearrangement Metathesis Strategy.
Authors: Escavabaja Philippe , Viala Jacques , Coquerel Yoann , Rodriguez Jean 
Published: April 2013

AbstractThe expeditious and stereocontrolled preparation of the bicyclic cores of cyclic polyethers of the dysiherbaine and acetogenin families includes an unprecedented ring rearrangement metathesis, involving the pyran moiety of oxabicyclo[3.2.1]octenes.
ChemInform Abstract: Palladium‐Catalyzed Highly Regioselective Arylation of Allylamines with Thiophenes and Furans.
Authors: Jiang Zhen , Zhang Lingjuan , Dong Chaonan , Cai Zhongzheng , Tang Weijun , Li Huanrong , Xu Lijin , Xiao Jianliang 
Published: April 2013

AbstractIn the presence of appropriate oxidants and a palladium catalyst N,N‐diprotected allylamines undergo terminal γ‐arylation with thiophenes and furans.
ChemInform Abstract: Enols as Feasible Acid Components in the Ugi Condensation.
Authors: Castellano Teresa G. , Neo Ana G. , Marcaccini Stefano , Marcos Carlos F. 
Published: April 2013

AbstractA high‐yielding three‐component reaction of imines, heterocyclic enols, and isocyanides is described to give a variety of heterocyclic enamines.
ChemInform Abstract: Preparation of Enantioenriched Iodinated Pyrrolinones by Iodocyclization of α‐Amino‐ynones.
Authors: Spina Rosella , Colacino Evelina , Gabriele Bartolo , Salerno Giuseppe , Martinez Jean , Lamaty Frederic 
Published: April 2013

AbstractDuring the synthesis of compounds (IV) partial racemization occurs.
ChemInform Abstract: The Synthesis of trans‐Perhydroindolic Acids and Their Application in Asymmetric Domino Reactions of Aldehyde Esters with β,γ‐Unsaturated α‐Keto Esters.
Authors: Shen Jiefeng , Liu Delong , An Qianjin , Liu Yangang , Zhang Wanbin 
Published: April 2013

AbstractA synthetic route towards trans‐perhydroindolic acid (VI), a key intermediate for preparation of trandolapril, as a mixture of four isomers is developed.
ChemInform Abstract: Rhodium‐Catalyzed Enantioselective 1,2‐Addition of Arylboronic Acids to Heteroaryl α‐Ketoesters for Synthesis of Heteroaromatic α‐Hydroxy Esters.
Authors: Wang Hui , Zhu Ting‐Shun , Xu Ming‐Hua 
Published: April 2013

AbstractCompared to established Friedel‐Crafts approaches the current method shows no dependence on the electronic nature of the substrates.
ChemInform Abstract: Diastereoselective Ruthenium Porphyrin‐Catalyzed Tandem Nitrone Formation/1,3‐Dipolar Cycloaddition for Isoxazolidines. Synthesis, in silico Docking Study and in vitro Biological Activities.
Authors: Reddy Annapureddy Rajasekar , Guo Zhen , Siu Fung‐Ming , Lok Chun‐Nam , Liu Fuli , Yeung Kai‐Chung , Zhou Cong‐Ying , Che Chi‐Ming 
Published: April 2013

AbstractThe described method features a broad scope of alkene compounds, excellent compatibility of various functionalities, neutral reaction conditions, and high regio‐, chemo‐ and diastereoselectivity.
ChemInform Abstract: Novel Synthesis of Pyrazolyloxothiazolidine Derivatives.
Authors: Hassan Alaa A. , Ibrahim Yusria R. , El‐Sheref Essmat M. , Aly Ashraf A. , Braese Stefan , Brown Alan B. 
Published: April 2013

AbstractThe title compounds (III) are obtained via microwave‐accelerated reaction of thioureas (I) with dimethyl acetylenedicarboxylate (II).
ChemInform Abstract: Hydrazonoyl Halides as Precursors for Synthesis of Novel Bioactive Thiazole and Formazan Derivatives.
Authors: Farghaly Thoraya A. , Abbas Eman M. H. 
Published: April 2013

AbstractSome of the novel derivatives synthesized, especially compounds (IIIa), (IIIb), (Vb), and (VIIb), exhibit promising activities against antibacterial and antifungal species.
ChemInform Abstract: Chemoselective Preparation of Unsymmetrical Bis(1,2,3‐triazole) Derivatives and Application in Bis(1,2,3‐triazole)‐Modified Peptidomimetic Synthesis.
Authors: Niu Teng‐fei , Gu Lin , Wang Liang , Yi Wen‐bin , Cai Chun 
Published: April 2013

AbstractSequential and one‐pot approaches to the preparation of unsymmetrical bistriazoles are presented.
ChemInform Abstract: (Iminophosphorane)copper(I) Complexes as Highly Efficient Catalysts for 1,3‐Dipolar Cycloaddition of Azides with Terminal and 1‐Iodoalkynes in Water: One‐Pot Multi‐Component Reaction from Alkynes and in situ Generated Azides.
Authors: Garcia‐Alvarez Joaquin , Diez Josefina , Gimeno Jose , Suarez Francisco J. , Vincent Cristian 
Published: April 2013

Abstract(Iminophosphorane)copper complexes, e.g. IPC, are efficient catalysts for the synthesis of triazoles under mild and aerobic conditions in aqueous media.
ChemInform Abstract: Solvent‐Free Huisgen Cyclization Using Heterogeneous Copper Catalysts Supported on Chelate Resins.
Authors: Monguchi Yasunari , Nozaki Kei , Maejima Toshihide , Shimoda Yutaka , Sawama Yoshinari , Kitamura Yoshiaki , Kitade Yukio , Sajiki Hironao 
Published: April 2013

AbstractNew copper catalysts supported on commercially available chelate resins possessing iminodiacetic acid (DIAION CR11) and polyamine moieties (DIAION CR20) are developed.
ChemInform Abstract: Imidazolium Ionic Liquids as Catalyst for Synthesis of (E)‐3‐Arylidene(thio)chroman‐4‐ones under Microwave Irradiation.
Authors: Li Hong‐Ya , Li Shu‐Na , Wang Quan , Wang Shu‐Xiang , Zhu Bao‐Cheng 
Published: April 2013

AbstractBoth employed imidazolium ionic liquids are found to be efficient catalysts in the title synthesis of arylidenechromanone derivatives (III) (21 examples in all).
ChemInform Abstract: Study of Substrate Dependence on the Chemoselectivity of the Gold‐Catalyzed Cycloisomerization of Aryl Substituted 1,7‐Enynes.
Authors: Huang Chuhui , Kothandaraman Prasath , Koh Bing Qin , Chan Philip Wai Hong 
Published: April 2013

AbstractThe substitution pattern of the starting material as well as the steric and electronic nature of the gold catalyst influence the chemoselectivity of this cycloisomerization.
ChemInform Abstract: 3‐Aryl‐6‐methoxy‐2‐oxo‐1,2‐dihydroquinoline‐4‐carbonitriles (VII) as Solvent and pH Independent Green Fluorescent Dyes
Authors: Enoua Guy Crepin , Uray Georg , Stadlbauer Wolfgang 
Published: April 2013

Abstractsynthesis and electronic spectra
ChemInform Abstract: Iodine‐Mediated Intramolecular Electrophilic Aromatic Cyclization in Allylamines: A General Route to Synthesis of Quinolines, Pyrazolo[4,3‐b]pyridines, and Thieno[3,2‐b]pyridines.
Authors: Batchu Harikrishna , Bhattacharyya Soumya , Batra Sanjay 
Published: April 2013

AbstractA unique method is developed to cyclize α‐aminomethyl β‐aryl or hetaryl substituted acrylic esters.
ChemInform Abstract: Synthesis of 4,6‐Disubstituted 2‐(4‐Morpholinyl)pyrimidines by Cross‐Coupling Reactions Using Triorganoindium Compounds.
Authors: Martinez M. Montserrat , Perez‐Caaveiro Cristina , Pena‐Lopez Miguel , Sarandeses Luis A. , Perez Sestelo Jose 
Published: April 2013

AbstractThis method allows the synthesis of symmetrical and non‐symmetrical 4,6‐disubstituted pyrimidine derivatives, which is a motif found in bioactive molecules.
ChemInform Abstract: Copper‐Catalyzed Cascade Synthesis of 1H‐Indolo[1,2‐c]quinazoline Derivatives.
Authors: Zhang Hao , Jin Yibao , Liu Hongxia , Jiang Yuyang , Fu Hua 
Published: April 2013

AbstractThe products can be easily constructed from o‐bromo‐ and o‐iodo‐phenyl indoles and amidines as starting materials.
ChemInform Abstract: Synthesis of 4‐Aminopyrazolo[3,4‐d]pyrimidine Derivatives from 5‐Acetyl‐6‐amino‐4‐methylsulfanyl‐ or 5‐Acetyl‐6‐amino‐4‐methylsulfonylpyrimidines.
Authors: Komkov A. V. , Voronkova V. A. , Shashkov A. S. , Dorokhov V. A. 
Published: April 2013

AbstractPyrazolo[3,4‐d]pyrimidines are successfully obtained starting from pyrimidines bearing vicinal acetyl and methylsulfanyl [cf.
ChemInform Abstract: Iridium‐Catalyzed Condensation of Amines and Vicinal Diols to Substituted Piperazines.
Authors: Lorentz‐Petersen Linda L. R. , Nordstroem Lars Ulrik , Madsen Robert 
Published: April 2013

AbstractPiperazines are prepared without any additives by using 1,2‐diamines and 1,2‐diols or via double condensation between a primary alkylamine and 1,2‐diol.
ChemInform Abstract: Highly Regioselective Synthesis of Fused Seven‐Membered Rings Through Copper‐Catalyzed Cross‐Coupling.
Authors: Sang Peng , Yu Ming , Tu Hangfei , Zou Jianwei , Zhang Yuhong 
Published: April 2013

AbstractAn efficient methodology for the synthesis of fused seven‐membered rings (III) from indole derivatives and 2‐halophenols is reported.