bluuebunny/crossref_metadata_2025_split huggingface dataset:
CluePedia Cytoscape plugin: pathway insights using integrated experimental and in silico data
Authors: Bindea Gabriela , Galon Jérôme , Mlecnik Bernhard 
Published: January 2013

Abstract
Summary: The CluePedia Cytoscape plugin is a search tool for new markers potentially associated to pathways. CluePedia calculates linear and non-linear statistical dependencies from experimental data. Genes, proteins and miRNAs can be connected based on in silico and/or experimental information and integrated into a ClueGO network of terms/pathways. Interrelations within each pathway can be investigated, and new potential associations may be revealed through gene/protein/miRNA enrichments. A pathway-like visualization can be created using the Cerebral plugin layout. Combining all these features is essential for data interpretation and the generation of new hypotheses. The CluePedia Cytoscape plugin is user-friendly and has an expressive and intuitive visualization.
Availability: http://www.ici.upmc.fr/cluepedia/ and via the Cytoscape plugin manager. The user manual is available at the CluePedia website.
Contact: bernhard.mlecnik@crc.jussieu.fr or jerome.galon@crc.jussieu.fr
Supplementary information: Supplementary data are available at Bioinformatics online.
Regulation of intestinal microbiota by the NLR protein family
Authors: Biswas Amlan , Kobayashi Koichi S. 
Published: January 2013

Abstract
The human intestine harbors a diverse microbial community consisting of a large number of bacteria and other micro-organisms that have co-evolved with the host intestinal immune system. During this process, microbiota and the host immune system shape one another by various mechanisms to achieve a successful symbiotic relationship. An increasing amount of evidence suggests that dysbiosis—the breakdown of such harmonized colonization—may result in infectious and inflammatory disorders, and recent advances in our studies indicate that receptors such as Toll-like receptors and NLR (nucleotide-binding oligomerization domain-like receptor; or nucleotide-binding domain- and leucine-rich repeat-containing receptor) proteins that detect micro-organisms and their products play a critical role in maintaining intestinal homeostasis. In this review, we summarize the role of NLR proteins in the regulation of intestinal microbiota. NLR proteins belong to a diverse family of cytoplasmic microbial sensors, mutations of which are involved in various disorders, including inflammatory bowel diseases. Understanding of the different roles of NLR family proteins in the intestine is, therefore, an important step towards the development of therapeutics against digestive diseases.
CSR failures in food supply chains – an agency perspective
Authors: Wiese Anne , Toporowski Waldemar 
Published: January 2013

PurposeCompanies implement corporate social responsibility (CSR) practices along their supply chains to fulfil stakeholder requirements. In doing so, failures in which CSR aspects are violated also emerge, caused by single supply chain members. In these situations, quite often the other supply chain members also appear responsible although they mostly do not have complete control over suppliers and sub‐suppliers due to information gaps. Therefore, the malpractice of one single company can harm the reputation of related companies. This paper aims to analyse recent CSR failures along food supply chains with the aim of evaluating why these occurred and what possibilities exist to avoid similar failures in the future.Design/methodology/approachAgency theory analyses information asymmetries in relationships in which one party delegates work to another party. In the considered failures, the downstream company can be regarded as principal by ordering products from the suppliers (agents). Consequently, agency theory contributes towards understanding failures in CSR implementation and highlighting solutions.FindingsThe cases analysed illustrate that CSR failures can have negative impacts on the companies' reputation and therefore also financial effects. Implementing a successful CSR policy should therefore be a primary interest of companies. Agency theory proved suitable to illustrate supply chain relationships and point out implications for companies. The instruments of agency theory can help to avoid CSR failures in food supply chains.Originality/valueThe paper combines agency theory with failures in CSR along food supply chains. In doing so, new insights into supply chain relationships are gained and implications for supply chain members to avoid CSR failures can be deduced. One special characteristic of the analysed failures is that the principal is not aimed at increasing the quantity of the agent's output but the quality.
The Southern Agrarians: a case study in intellectualized collection development
Authors: Dilevko Juris 
Published: January 2013

PurposeThe purpose of this paper is to present a case study about how academic librarians can contribute to the interdisciplinary research endeavors of professors and students, especially doctoral candidates, through an intellectualized approach to collection development.Design/methodology/approachIn the wake of protest movements such as the Tea Party and Occupy Wall Street, colleges and universities have begun to develop courses about these events, and it is anticipated that there will be much research conducted about their respective histories. Academic librarians can participate in those research efforts by developing interdisciplinary collections about protest movements and by referring researchers to those collections.FindingsThrough a case‐study approach, this paper provides a narrative bibliography about Southern Agrarianism that can help professors and students interested in the Tea Party or Occupy Wall Street movements to see their research endeavors from a new interdisciplinary perspective.Originality/valueThe value of this paper lies in presenting a concrete example of the way in which academic librarians can become active research partners through the work of building collections and recommending sources in areas that professors and students may not have previously considered.
Quantitative assessment of dual gait analysis based on inertial sensors with body sensor network
Authors: Wang Zhelong , Qiu Sen , Cao Zhongkai , Jiang Ming 
Published: January 2013

PurposeDue to the complex mechanism during walking, human gait takes plenty of information reflecting human motion. The method of quantitative measurement of gait makes a profound influence in many fields, such as clinical medicine, biped robot control strategy and so on. The purpose of this paper is to present a gait analysis system based on inertial measurement unit (IMU) and combined with body sensor network (BSN).Design/methodology/approachThe authors placed two wireless inertial nodes on the left and right ankles, so that the acceleration and angular velocity could be obtained from both sides at the same time. By using the kinematical model of the human gait, many methods such as time series analysis, pattern recognition and numerical analysis, are introduced to fuse the inertial data and estimate the sagittal gait parameters.FindingsThe gait parameters evaluation gains a practical precision, especially in the gait phase detection and the process of how the two feet cooperate with each other has been analyzed to learn about the mechanism of biped walking.Research limitations/implicationsThe gait analysis procedure is off line, so that the system ensures sampling at a high rate.Originality/valueThis gait analysis system can be utilized to measure quantitative gait parameters. Further, the coordination of dual gait pattern is presented. Last but not least, the system can also be put into capturing and analyzing the motion of other parts of the body.
Can facility managers impact the expected budgetary outcomes of robust asset management programs?
Authors: Rogers Jeffrey W. 
Published: January 2013

PurposeThe purpose of this paper is to present a conceptual risk assessment technique to aid facility managers with developing robust asset management programs. It proposes to evaluate three discrete risk sensitivity levels relative to the recognition of stochastic costs on expected budgetary outcomes. The paper expands the domain of available risk assessment techniques toward estimating impacts from uncertainty on desired levels of service.Design/methodology/approachThe paper explores the concept that facility managers can cost‐effectively manage robust asset management programs. This is accomplished by evaluating simple relationships between risk‐sensitive decision‐response alternatives and systems degradation characteristics. The resulting parameters are aggregated to estimate expected budgetary outcomes for robust asset management programs.FindingsThe paper reveals that if facility managers assume risk‐avoidance positions, they can positively affect expected budgetary outcomes for robust asset management programs. Facility managers can manage the magnitude of these adverse impacts by mitigating stochastic costs associated with the completion of unscheduled asset management activities.Research limitations/implicationsThe expected implications are enhancements to the abilities of facility managers to cost‐effectively manage stochastic costs relative to risk sensitivity and desired levels of service. However, because of the chosen research approach, the research results may lack general usability. Therefore, researchers are encouraged to test the proposed propositions further.Practical implicationsThe practical implications allow facility managers to cost‐effectively manage adverse impacts on expected budgetary outcomes for robust asset management programs.Social implicationsThe expected contribution is a tool for facility managers to manage uncertainty when allocating limited financial resources among the competing corrective, maintenance, and rehabilitation activities within robust asset management programs.Originality/valueThe paper fulfills an identified need to study how facility managers can do more with less. This need to be cost‐effective requires facility managers to recognize stochastic costs on the expected budgetary outcomes for robust asset management programs.
Analytic hierarchy process approach for competitive property management attributes
Authors: Lo Kak K. , Hui Eddie C.M. , Ching Ringo H.F. 
Published: January 2013

PurposeThe property service agents (PSAs) are the outsourced agents of Hong Kong Housing Authority (HKHA), who manage the HKHA's rental properties in a competitive environment. To enhance the competitiveness edges of these PSAs under the inelastic management fee constraint, it is prudent for them to acknowledge those competitive property management attributes upon which PSAs reallocate their limited internal resources to best meet the expectations of the tenants.Design/methodology/approachAnalytic hierarchy process (AHP) was adopted for revealing the preference of tenants on those captioned attributes under a ratio scale. The data were collected through face‐to‐face interviews with the representatives of tenants of housing estates including but not limited to chairmen of Mutual Aid Committees and District Councilors.FindingsThe findings indicated that, amongst all competitive property management attributes, tenants of older housing estates preferred a higher level of repairs and maintenance, while those tenants of younger and larger population housing estates focused more on environmental control issues.Practical implicationsWithout an objective quantitative analysis of tenants' preferences, the PSAs might render misallocation of limited resources, which would not only jeopardize their survival in the competitive commercial world but also upset the expectation of the tenants.Originality/valueThe use of quantitative study to solicit the preferences of public housing tenants on property management attributes is the first kind of study which provides comprehensive knowledge of tenants' preferences and could enable PSAs to enhance their competitiveness in the commercial world under the constraints of inelastic management fees structure.
Understanding informal feedback seeking in the workplace
Authors: van der Rijt Janine , Van den Bossche Piet , S.R. Segers Mien 
Published: January 2013

Purpose
– The purpose of this study is to investigate whether the position of employees in the organizational hierarchy is important in explaining their feedback seeking behaviour.

Design/methodology/approach
– This study takes a social network perspective by using an ego-centric network survey to investigate employees
'
feedback seeking behaviour within their professional networks. Data were collected from an online questionnaire among 243 employees working in a large multinational organization located in The Netherlands.

Findings
– Results indicate that employees frequently seek feedback from colleagues within the same department. However, managers or leaders seek significantly less feedback from colleagues in the same department and from coaches, as compared to others. Furthermore, employees perceive the feedback they receive from managers/leaders, coaches, and colleagues in the same department as useful.

Originality/value
– The study findings extend the existing literature on the dynamics of feedback seeking of employees across different hierarchical levels. Methodologically, an egocentric network survey was used to investigate the employees
'
relationships within their professional network. The findings suggest that this approach, novel in research on feedback seeking, is valuable and promising.
The impact of feedback training for inspectors
Authors: J. Dobbelaer Marjoleine , J. Prins Frans , van Dongen Dré 
Published: January 2013

Purpose
– The purpose of this paper is to explore whether oral feedback by inspectors of the Dutch Inspectorate of Education is an adequate method to support the professional development of teachers in primary education. This study aims to examine the impact of short feedback training for inspectors (focused on effective feedback conversations) on feedback quality and on teachers
'
feedback perception. In addition, it aims to study the relation between immediate perception and the delayed perception of that feedback.

Design/methodology/approach
– In an independent sample experimental design, 15 inspectors provided feedback to 40 teachers in primary education. Nine inspectors received short feedback training (the experimental group), while six others did not receive this training (the control group).

Findings
– The results indicate that feedback provided by trained inspectors can foster professional development of teachers in primary education and that short feedback training has added value. The quality of the feedback by inspectors was related to teachers
'
immediate perception of the feedback and the delayed perception of the feedback.

Research limitations/implications
– A limitation of this study is the small group of inspectors and the limited number of feedback conversations they could provide. Further research could be aimed at examining the impact of feedback of trained inspectors on the professional development of underperforming teachers.

Originality/value
– This paper contributes to research that examines effective ways to use feedback conversations in workplace settings for the professional development of teachers.
School leadership practice and preparation
Authors: Ylimaki Rose , Jacobson Stephen 
Published: January 2013

PurposeThe aim of this paper is to utilize successful leadership practices drawn from seven nations to improve leadership preparation.Design/methodology/approachThis study used a case study approach to gain a contextualized understanding of successful leadership across seven nations. Data sources primarily featured interviews with principals, teachers, staff members, parents, and students. Cases were analyzed within and then across nations with regards to organizational learning (OL), instructional leadership (IL), and culturally responsive practices (CRP).FindingsThe cross‐national analysis of successful leaders indicated emerging policy trends, demographic changes, similarities and differences among leaders, and recommendations for leadership preparation.Originality/valueThis paper draws from successful practices in OL, IL and CRP in seven nations to make recommendations for improving leadership preparation.
Developing the next generation of black and global majority leaders for London schools
Authors: Johnson Lauri , Campbell‐Stephens Rosemary 
Published: January 2013

PurposeThe aim of this paper is to discuss the views of black and ethnic minority school leaders about the Investing in Diversity program, a black‐led program developed in 2004 to address the underrepresentation of black leaders in the London schools. Major themes are identified from interviews with black and South Asian women graduates of the program and recommendations made for leadership development strategies to help aspiring and current black and global majority headteachers “bring who they are” to their leadership.Design/methodology/approachQualitative case study data about the Investing in Diversity program include document analysis of curriculum modules and participant observation of the weekend residential, survey satisfaction data from several cohorts, and face‐to‐face interviews with a purposive sample of seven headteachers from African Caribbean, African, and South Asian backgrounds who completed the Investing in Diversity program six‐seven years ago. These semi‐structured individual interviews were conducted in the spring of 2012 during an all‐day visit to their schools and focused on barriers and supports in their career path, approach to leadership, and their views on their leadership preparation.FindingsParticipants identified black and ethnic minority headteachers as role models, the importance of mentoring and informal networks, and opportunities to lead as supports to their career path to headship. Many of their long‐term informal networks were established with other BME colleagues who attended Investing in Diversity. Barriers included subtle (and not so subtle) discrimination from parents, teachers, and administrators for some of the participants.Research limitations/implicationsObservational studies and interview studies, which included a bigger sample of black and ethnic minority headteachers, would extend this research.Practical implicationsThis study provides suggestions for schools and local authorities about leadership preparation strategies that make a difference for aspiring BME leaders.Originality/valueThere is a paucity of research on the views of British BME headteachers. This study adds to the research base on BME leadership development in Britain and contributes to international research on self‐defined black leadership perspectives.
Developing tools for research on school leadership development
Authors: Showanasai Parinya , Lu Jiafang , Hallinger Philip 
Published: January 2013

PurposeThe extant literature on school leadership development is dominated by conceptual analysis, descriptive studies of current practice, critiques of current practice, and prescriptions for better ways to approach practice. Relatively few studies have examined impact of leadership development using experimental methods, among which even fewer studies have employed a cross‐cultural comparative perspective. The aim of this paper is to discuss the feasibility of using a computer simulation as tools for research in leadership development.Design/methodology/approachThis is a methodology development paper. It discusses the feasibility of using a computer simulation as tools for research in leadership development. Exemplary research questions, research designs, and data analyses are used to illustrate the potential of this approach for addressing under‐explored issues in management education.FindingsThree categories of cross‐cultural comparative research questions are proposed: comparative study of leadership expertise, comparative study of instructional approaches, and comparative study of leadership development processes. This study demonstrates the research potential of using the computer simulations to address complex issues in leadership development across cultures.Originality/valueAlthough computer simulations have been used as training tools for several decades, few scholars have explored their potential for use in the collection of complex data in an efficient fashion. The current study not only demonstrates how a specific simulation has been adapted to collect data on leadership development in education, but also models the means by which computer simulations could be employed in a similar fashion in other domains of education and training.
How to keep the talent you have got
Authors: Bagga Gaurav 
Published: January 2013

PurposeThe purpose of this paper is to examine where high rates of employee attrition are a problem and put forward some possible solutions.Design/methodology/approachThe paper concentrates on the experience of information technology (IT) firms in India.FindingsThe paper describes how employees seem most likely to leave a company after around five years. The longer an employee remains with a company, the less likely he or she is to leave.Practical implicationsThe paper highlights the importance of making employees feel valued, keeping them informed of what is going on in the company, relating their work to the aims of the organization as a whole and ensuring that they have a clear career‐development path.Social implicationsThe paper stresses that high rates of employee attrition can harm not only individual companies, but also national economies as a whole.Originality/valueThe paper focuses on the IT industry in India to recommend how to reduce employee attrition.
Vodafone puts mobility at the heart of business strategy
Authors: Webb Nick 
Published: January 2013

PurposeThe purpose of this paper is to chart Vodafone's journey from a conventional office‐based business to a new, uncharted, largely mobile and dynamic strategy.Design/methodology/approachThe paper highlights some of the operational and cultural challenges that the company had to overcome along the way, the advantages the changes have brought and the lessons the company has learned.FindingsThe paper explains that, since unified communications were adopted throughout the organization, employees are able to pick up messages and no longer need to miss any call. This seamless service has improved the speed and quality of customer service, slashing decision times and enabling smarter, more informed working. Pricing changes that could take up to 90 days to execute now take only four days. Customer complaints have also dropped by 57 percent in two years.Practical implicationsThe paper reveals that productivity has increased by 15 percent, employees' work‐life balance has improved, and flexibility and openness to change have become embedded in the organizational culture.Social implicationsThe paper describes how employees can use their time more effectively, partly because flexible working enables them to spend less time commuting.Originality/valueThe paper details the lessons that a major multinational company learned from a program of significant organizational change.