bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: 1,3‐Dipolar Cycloadditions of Nitrile Oxides with 7‐Oxa‐ and 7‐Azabenzonorbornadienes.
Authors: Nagireddy Jaipal R. , Carlson Emily , Tam William 
Published: December 2014

Abstract1,3‐Dipolar cycloadditions of 7‐oxa‐ and 7‐azabenzonorbornadienes with in situ generated nitrile oxides afford exclusively exo‐cycloadducts.
ChemInform Abstract: Redox‐Neutral Iron—Sulfur Promoted Transformation of 2‐Nitrophenols and 2,6‐Disubstituted p‐Cresols into 2‐Arylbenzoxazoles.
Authors: Saibara Masahiko , Ashida Kazuhito , Satomi Kouji , Iwai Toshiyuki , Nakai Takeo , Mihara Masatoshi , Ito Takatoshi , Mizuno Takumi 
Published: December 2014

AbstractSubstitution of 2,6‐di‐tert‐butyl‐p‐cresol (II) by 2‐tert‐butyl‐p‐cresol, 2,6‐dimethoxy‐p‐cresol or 1‐tert‐butyl‐toluene results in the isolation of the corresponding products in small or trace amounts only.
ChemInform Abstract: Glycerol: A Biorenewable Solvent for Base‐Free Cu(I)‐Catalyzed 1,3‐Dipolar Cycloaddition of Azides with Terminal and 1‐Iodoalkynes. Highly Efficient Transformations and Catalyst Recycling.
Authors: Vidal Cristian , Garcia‐Alvarez Joaquin 
Published: December 2014

AbstractCuAAC reactions in glycerol as solvent are studied.
ChemInform Abstract: Design, Synthesis and Antiproliferative Activity of Functionalized Flavone‐triazole‐tetrahydropyran Conjugates Against Human Cancer Cell Lines.
Authors: Ahmed Naseem , Konduru Naveen Kumar , Ahmad Sarfaraz , Owais Mohammad 
Published: December 2014

AbstractThe title compounds were synthesized and tested against three human cancer cell lines (MDA‐MB 231, KCL22, and HeLa).
ChemInform Abstract: Synthesis of 3‐Aminochromenes: The Zincke Reaction Revisited.
Authors: Costa Marta , Rodrigues Ana I. , Proenca Fernanda 
Published: December 2014

Abstract3‐Aminocoumarins (II) and 2‐iminochromen‐3‐amines (IV) are prepared via Zincke‐ring‐opening reaction of corresponding chromen‐3‐pyridinium chlorides (I) and (III), resp., using N‐methylpiperazine.
ChemInform Abstract: Chemoselective Route for Synthesis of N‐Aryl‐3‐oxochromeno[2,3‐c]pyrazole‐2(3H)‐carbothioamide Derivatives
Authors: Alizadeh Abdolali , Ghanbaripour Rashid 
Published: December 2014

Abstractvia multi‐component reaction of various aryl isothiocyanates, salicylaldehydes, malononitrile and hydrazine hydrate
ChemInform Abstract: One‐Pot Synthesis of Novel Pyrano‐Fused Coumarins Catalyzed by ZnO Nanoparticles.
Authors: Khodabakhshi Saeed , Eskandari Khalil , Karami Bahador 
Published: December 2014

Abstract10 Title compounds of type (IV) are prepared using ZnO nanoparticles as catalyst.
ChemInform Abstract: Chemoenzymatic Preparation of Optically Active 4‐Aryl‐5‐carboxy‐6‐methyl‐3,4‐dihydro‐2(1H)‐pyridone Derivatives.
Authors: Torres Susana Y. , Ochoa Estael , Verdecia Yamila , Rebolledo Francisca 
Published: December 2014

AbstractAn efficient route is elaborated to prepare pyridone substrates of type (VII) bearing an ester group which can be easily hydrolyzed.
ChemInform Abstract: Synthesis of Phenanthridin‐6‐yldiphenylphosphine Oxides by Oxidative Cyclization of 2‐Isocyanobiphenyls with Diarylphosphine Oxides.
Authors: Li Yuewen , Qiu Guanyinsheng , Ding Qiuping , Wu Jie 
Published: December 2014

AbstractThe important phosphonated heterocyclic system is formed with high regioselectivity and various functionalities are tolerated.
ChemInform Abstract: Synthesis and Reactions of 2‐Pyrido‐Fused Bicyclic Compounds.
Authors: Chou Shang‐Shing P. , Wu Yi‐Ting 
Published: December 2014

AbstractA new method is given for the preparation of pyrido‐fused bicyclic compounds of type (III) whereas, compound (IIb) is used as starting material for some related compounds.
ChemInform Abstract: Approaches for the Introduction of Fluorinated Substituents into [1,2,3]Triazolo[1,5‐a]pyridines.
Authors: Chiassai Leonardo , Adam Rosa , Drechslerova Marcela , Ballesteros Rafael , Abarca Belen 
Published: December 2014

AbstractFunctionalization of [1,2,3]triazolo[1,5‐a]pyridines with a trifluoromethyl group is achieved for the first time.
ChemInform Abstract: New Convenient Synthesis of Fluorescent 1,8‐Naphthyridines and the Metal‐Sensing Properties of the Dyes.
Authors: Goel Atul , Nag Pankaj , Umar Shahida 
Published: December 2014

AbstractThe photophysical properties of products (III) and (V) and the metal sensing capability of (Va) are examined.
ChemInform Abstract: Synthesis of Polyacrylonitrile Fiber‐Supported Poly(ammonium methanesulfonate)s as Active and Recyclable Heterogeneous Broensted Acid Catalysts.
Authors: Shi Xian‐Lei , Xing Xiaoli , Lin Huikun , Zhang Wenqin 
Published: December 2014

AbstractThe synthesis of the catalyst and its recyclability (ten cycles without loss of activity) is described.
ChemInform Abstract: An Efficient One‐Pot Synthesis of 1,2,4‐Triazoloquinoxalines.
Authors: Niu Xiaoyi , Yang Bingchuan , Fang Shuai , Li Yanqiu , Zhang Zeyuan , Jia Jiong , Ma Chen 
Published: December 2014

AbstractThe formation of the pharmaceutically important skeleton becomes possible under optimized conditions A) which are applied to a broad spectrum of substrates.
ChemInform Abstract: Synthesis and Biological Evaluation of Substituted 2‐Anilino‐7H‐pyrrolopyrimidines as PDK1 Inhibitors.
Authors: O'Brien Nathan J. , Brzozowski Martin , Wilson David J.D. , Deady Leslie W. , Abbott Belinda M. 
Published: December 2014

AbstractTitle compounds (V) are synthesized via sequential Suzuki coupling of dichloro‐pyrrolopyrimidine (I) with boronate (II) followed by Buchwald—Hartwig cross‐coupling with various customized anilines (IV).
ChemInform Abstract: A Novel Synthesis of Quinazolines by Cyclization of 1‐(2‐Isocyanophenyl)alkylideneamines Generated by the Treatment of 2‐(1‐Azidoalkyl)phenyl Isocyanides with NaH.
Authors: Ezaki Kosuke , Kobayashi Kazuhiro 
Published: December 2014

AbstractThe method is efficient and can be successfully applied to the synthesis of related 7‐aza‐analogues (VI).
ChemInform Abstract: Azomethine Ylides Derived from Alkyl‐(3‐oxopiperazin‐2‐yl)acetates in 1,3‐Dipolar Cycloaddition Reactions with N‐Aryl Maleimides.
Authors: Medvedeva S. M. , Stashina G. A. , Firgang S. I. , Malikova E. S. , Krysin M. Yu. , Shikhaliev Kh. S. 
Published: December 2014

AbstractThe title cycloaddition reaction furnishes representatives of a new heterocyclic system, decahydropyrrolopyrrolopyrazine, as a mixture of exo‐ and endo‐diastereomers.
ChemInform Abstract: The Interaction of 2,5‐Diethoxycarbonyl‐ and 5‐Benzoyl‐2‐ethoxycarbonyl‐4‐pyrones with o‐Phenylenediamine.
Authors: Obydennov D. L. , Sosnovskikh V. Ya. 
Published: December 2014

AbstractThe title reaction affords enedioates (III) which easily cyclize into new derivatives of pyrido[1,2‐a]quinoxaline system (IV).
ChemInform Abstract: Triazene Derivatives of (1,χ)‐Diazacycloalkanes. Part 10. Synthesis and Characterization of a Series of 1,4‐Di[2‐aryl‐1‐diazenyl]‐trans‐2,5‐dimethylpiperazines.
Authors: Little Vanessa Renee , Tingley Reid , Vaughan Keith 
Published: December 2014

Abstract13 Title compounds of type (III) are prepared and their 1H and 13C NMR spectra are discussed in detail.
ChemInform Abstract: New Method for Synthesis of the Hetero‐Cyclic System — 1,2,3,4‐Tetrahydroimidazo[5,1‐f][1,2,4]triazin‐7‐amine.
Authors: Vandyshev D. Yu. , Shikhaliev Kh. S. , Potapov A. Yu. , Firgang S. I. , Krysin M. Yu. 
Published: December 2014

Abstractusing the three‐component reaction of 1,2‐diaminoimidazoles (I) with primary amines and formaldehyde
ChemInform Abstract: Chemoselective Amination of Propargylic C(sp3)—H Bonds by Cobalt(II)‐Based Metalloradical Catalysis.
Authors: Lu Hongjian , Li Chaoqun , Jiang Huiling , Lizardi Christopher L. , Zhang X. Peter 
Published: December 2014

AbstractFor the first time, a cobalt/porphyrin‐based complex is used for the chemoselective intramolecular amination of propargylic C(sp3)—H bonds in N‐bishomopropargylic sulfamoyl azides.
ChemInform Abstract: Tuning Thiophene with Phosphorus: Synthesis and Electronic Properties of Benzobisthiaphospholes.
Authors: Noonan Kevin J. T. , et al. et al. 
Published: December 2014

AbstractBenzobisthiaphospholes are prepared by condensation of bismercapto‐bisphosphinobenzenes of type (I) with carboxylic acid chlorides.
ChemInform Abstract: Face to Face Activation of a Phenylselenium Borane with α,β‐Unsaturated Carbonyl Substrates: Facile Synthesis of C—Se Bonds.
Authors: Sanz Xavier , Vogels Christopher M. , Decken Andreas , Bo Carles , Westcott Stephen A. , Fernandez Elena 
Published: December 2014

AbstractActivated olefins directly react with phenylselenium borane (II) without any metal or organocatalytic assistance.
ChemInform Abstract: Diastereoselective Total Synthesis of Salvileucalin C.
Authors: Fu Chenchen , Zhang Yuanbao , Xuan Jun , Zhu Chenlong , Wang Bingnan , Ding Hanfeng 
Published: December 2014

AbstractThe preparation of salvileucalin C (I) and its biosynthetically related diterpenoids salvileucalin D (II), salvipuberulin (III), isosalvipuberulin (IV) and dugesin B (V) is achieved.
ChemInform Abstract: A Mild Method for the Synthesis of a Novel Dehydrobutyrine‐Containing Amino Acid.
Authors: Webster Alexandra M. , Coxon Christopher R. , Kenwright Alan M. , Sandford Graham , Cobb Steven L. 
Published: December 2014

AbstractThe reaction between the amino acid ester (I) and pentafluoropyridine in the presence of potassium carbonate causes the desired elimination reaction to form the desired product.
ChemInform Abstract: Synthesis of Branched Carbasugars via Photooxygenation and Manganese(III) Acetate Free Radical Cyclization.
Authors: Altun Yasemin , Dogan Sengul Dilem , Balci Metin 
Published: December 2014

AbstractTransformation of cyclohexadienes (I) and (IX) to carbasugars (VIII) and (XII), resp., is described.
ChemInform Abstract: Synthesis of 1‐Indolyl Substituted β‐Carboline Natural Products and Discovery of Antimalarial and Cytotoxic Activities.
Authors: Liew Lydia P. P. , Fleming Jessica M. , Longeon Arlette , Mouray Elisabeth , Florent Isabelle , Bourguet‐Kondracki Marie‐Lise , Copp Brent R. 
Published: December 2014

AbstractA series of 1‐indolyl substituted β‐carbolines including the natural products hyrtiosulawesine (Ia), pityriacitrin (Ib) and pityriacitrin B (Ic) are prepared via a Pictet—Spengler condensation‐oxidation strategy from the corresponding indolyl aldehydes and substituted tryptamines.
ChemInform Abstract: An Efficient Method for the Preparation of 3‐Hydroxyl‐5‐substituted 2‐Pyrrolidones and Application in the Divergent Synthesis of (‐)‐Preussin and Its Analogues.
Authors: Zhou Qian‐Ru , Wei Xiao‐Yun , Li You‐Qin , Huang Danfeng , Wei Bang‐Guo 
Published: December 2014

AbstractThis describes the syntheses of (‐)‐preussin (XIb) and analogues (XI).
ChemInform Abstract: Four New Ginkgolic Acids from Ginkgo biloba.
Authors: Deguchi Jun , Hasegawa Yuki , Takagi Ayana , Kutsukake Shihoko , Kono Mizue , Hirasawa Yusuke , Wong Chin Piow , Kaneda Toshio , Morita Hiroshi 
Published: December 2014

AbstractThe compounds (I) and (II) are examined as an inseparable mixture of isomers and are ultimately defined by total synthesis.
ChemInform Abstract: Kaempferol, a Potential Cytostatic and Cure for Inflammatory Disorders
Authors: Rajendran Peramaiyan , Rengarajan Thamaraiselvan , Nandakumar Natarajan , Palaniswami Rajendran , Nishigaki Yutaka , Nishigaki Ikuo 
Published: December 2014

AbstractReview: 125 refs.
Interaction effects between weather and space use on harvesting effort and patterns in red deer
Authors: Rivrud Inger M. , Meisingset Erling L. , Loe Leif E. , Mysterud Atle 
Published: December 2014

AbstractMost cervid populations in Europe and North America are managed through selective harvesting, often with age‐ and sex‐specific quotas, with a large influence on the population growth rate. Less well understood is how prevailing weather affects harvesting selectivity and off‐take indirectly through changes in individual animal and hunter behavior. The behavior and movement patterns of hunters and their prey are expected to be influenced by weather conditions. Furthermore, habitat characteristics like habitat openness are also known to affect movement patterns and harvesting vulnerability, but how much such processes affect harvest composition has not been quantified. We use harvest data from red deer (Cervus elaphus) to investigate how weather and habitat characteristics affect behavioral decisions of red deer and their hunters throughout the hunting season. More specifically, we look at how sex and age class, temperature, precipitation, moon phase, and day of week affect the probability of being harvested on farmland (open habitat), hunter effort, and the overall harvest numbers. Moon phase and day of week were the strongest predictors of hunter effort and harvest numbers, with higher effort during full moon and weekends, and higher numbers during full moon. In general, the effect of fall weather conditions and habitat characteristics on harvest effort and numbers varied through the season. Yearlings showed the highest variation in the probability of being harvested on farmland through the season, but there was no effect of sex. Our study is among the first to highlight that weather may affect harvesting patterns and off‐take indirectly through animal and hunter behavior, but the interaction effects of weather and space use on hunter behavior are complicated, and seem less important than hunter preference and quotas in determining hunter selection and harvest off‐take. The consideration of hunter behavior is therefore key when forming management rules for sustainable harvesting.
Population divergence in compensatory growth responses and their costs in sticklebacks
Authors: Ab Ghani Nurul Izza , Merilä Juha 
Published: December 2014

AbstractCompensatory growth (CG) may be an adaptive mechanism that helps to restore an organisms’ growth trajectory and adult size from deviations caused by early life resource limitation. Yet, few studies have investigated the genetic basis of CG potential and existence of genetically based population differentiation in CG potential. We studied population differentiation, genetic basis, and costs of CG potential in nine‐spined sticklebacks (Pungitius pungitius) differing in their normal growth patterns. As selection favors large body size in pond and small body size in marine populations, we expected CG to occur in the pond but not in the marine population. By manipulating feeding conditions (viz. high, low and recovery feeding treatments), we found clear evidence for CG in the pond but not in the marine population, as well as evidence for catch‐up growth (i.e., size compensation without growth acceleration) in both populations. In the marine population, overcompensation occurred individuals from the recovery treatment grew eventually larger than those from the high feeding treatment. In both populations, the recovery feeding treatment reduced maturation probability. The recovery feeding treatment also reduced survival probability in the marine but not in the pond population. Analysis of interpopulation hybrids further suggested that both genetic and maternal effects contributed to the population differences in CG. Hence, apart from demonstrating intrinsic costs for recovery growth, both genetic and maternal effects were identified to be important modulators of CG responses. The results provide an evidence for adaptive differentiation in recovery growth potential.
Improved Electrical Energy Storage Density in Vanadium‐Doped BaTiO3 Bulk Ceramics by Addition of 3BaO–3TiO2–B2O3 Glass
Authors: Patel Satyanarayan , Chauhan Aditya , Vaish Rahul 
Published: December 2014

AbstractThis study proposes to significantly improve the electrical energy storage characteristics of BaTiO3 bulk ceramics. Addition of 3 BaO–3 TiO2–B2O3 glass was done in controlled amounts to study its effect on the ferroelectric response and storage characteristics of vanadium‐doped BaTiO3 samples. The energy density for the composites was calculated using hysteresis loops. It was observed that a significant improvement in the energy storage density can be obtained by addition of 1 % (weight) 3 BaO–3 TiO2–B2O3 glass. The addition of glass in small amounts was also observed to impart additional benefits such as increased saturation polarization and a thermally invariant ferroelectric response.
Aquifer–peatland connectivity in southern Quebec (Canada)
Authors: Ferlatte Miryane , Quillet Anne , Larocque Marie , Cloutier Vincent , Pellerin Stéphanie , Paniconi Claudio 
Published: December 2014

AbstractIn areas where peatlands are abundant, they are likely to play a significant role in the hydrological and hydrogeological dynamics of a watershed. Although individual case studies are reported in the literature, there is a large range of aquifer–peatland interactions and there is a need to understand the controls of these interactions. The objectives of this study were (1) to better understand aquifer–peatland connections and how these may be predicted by geology and geomorphic location and (2) to provide a variety of reference sites for glacial geological settings. Slope and depression peatlands were studied in the Abitibi‐Témiscamingue region and in the St. Lawrence Lowlands, two contrasting regions of southern Quebec. A total of 12 transects that span a shallow aquifer–peatland interface were instrumented with piezometers. Field investigations included peatland characterization, monthly water level monitoring, and continuous hydraulic head measurements with pressure transducers. The results indicate that 7 of the 12 transects receive groundwater from the surrounding shallow aquifer. At the peatland margin, four lateral flow patterns were identified and associated with slope peatlands (parallel inflow and divergent flow) and with depression peatlands (convergent flow and parallel outflow). Vertical hydraulic gradients suggest that water flows mainly downwards, i.e. from the peatland to the underlying mineral deposits. Vertical connectivity appears to decrease as the distance from the peatland margin increases. All of these exchanges are important components in the sustainability of peatland hydrogeological functions. The regional comparison of aquifer–peatland flow dynamics performed in this study provides a new set of referenced data for the assessment of aquifer–peatland connectivity. Copyright © 2014 John Wiley & Sons, Ltd.
Induction of GADD45α protects M17 neuroblastoma cells against MPP*
Authors: Wang Xiao‐Feng , Zeng Qing‐gan , Zeng Yan , Man Rong‐Yong , Lu Bing‐Xun , Luo Yi‐Feng 
Published: December 2014

AbstractGrowth arrest and DNA‐damage‐inducible protein 45α (GADD45α) is an important member of the family of growth arrest and DNA damage‐inducible (GADD) proteins. The expression patterns and possible roles of GADD45α in Parkinson's disease (PD) are so far less understood. In this study, we found that 1‐methyl‐4‐phenylpyridinium (MPP+) treatment up‐regulates the expression of GADD45α in both a time‐dependent manner and a dose‐dependent manner in human dopamine neuroblastoma M17 cells. The up‐regulation of GADD45α was abolished by pretreatment with the c‐Jun N‐terminal kinases (JNK) inhibitor SP600125 but not the p38 specific inhibitor SB203580. Further study revealed that c‐Jun silencing abolished the effects of MPP+ on the expression of GADD45α. Important, ChIP studies verified the ability of c‐Jun to bind to the GADD45 promoter. In addition, we found that inhibition of GADD45α by small RNA interference exacerbates the impaired cell viability, LDH release, and apoptosis induced by MPP+. Correspondingly, silence of GADD45 exacerbated Caspase‐3 activation induced by MPP+. These data suggested a neuroprotective effect of GADD45α against MPP+ neurotoxicity. © 2014 IUBMB Life, 66(11):786–792, 2014
Humid Bonding with a Water‐Soluble Adhesive Inspired by Mussels and Sandcastle Worms
Authors: Li Ailei , Jia Mingchen , Mu Youbing , Jiang Wei , Wan Xiaobo 
Published: December 2014

Inspired by mussels and sandcastle worms, a water‐soluble adhesive is prepared by grafting catechol and phosphoric acid functionalities to the polyoxetane backbone, which achieves improved adhesion in humid environment. The adhesive is characterized by 1H and 31P NMR spectroscopy and size‐exclusive chromatography. The influence of the content ratio of catechol and different phosphoric acid groups and the Fe3+ ions as the crosslinker on the outcome of the adhesive properties is investigated. When the molar ratio of Fe3+ to catechol and PO4 is 1/1 and 0.7/1, respectively, the best bonding strength of 0.35 MPa is achieved for the adhesive containing 5 mol% catechol and 26 mol% bis‐phosphoric acid groups under humid conditions. It is found out that Fe3+ interacts not only with the catechol, but also with the bis‐phosphoric acid groups, which accounts for its performance in humid conditions.
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The Understanding of Pain by Older Adults Who Consider Themselves to Have Aged Successfully
Authors: Collis David , Waterfield Jackie 
Published: December 2014

AbstractObjectivesDespite an ageing population and an increased prevalence of chronic pain, the relationship between chronic pain and the concept of successful ageing is unclear. The aim of the present research was to explore older people's views on past and present experiences of pain, and its management, and how these experiences relate to their perceptions of successful ageing.MethodsSemi‐structured interviews with six participants, aged 75 years or older, who considered themselves to have aged successfully, explored what this concept meant to them and their experiences of pain. Data analysis used methods drawn from grounded theory. The themes reported in this article are ‘understanding of pain’ and ‘perceptions of ageing’.ResultsNone of the participants recalled painful experiences that were not attributable to physical trauma. They believed that pain is part of life and a natural consequence of the ageing process. While some accepted this with little resistance, others felt frustration at what they considered a dismissive attitude towards older people experiencing pain from healthcare practitioners. The concept of successful ageing was previously unfamiliar to participants, and their conceptualization of ageing derived from comparing themselves with their peers.ConclusionsThe findings of the present study suggest that predictable experiences of pain as one ages may contribute to an acceptance of pain as a biomedical certainty, a belief reinforced both by health professionals and society. However, one may have chronic pain and yet consider oneself to have aged successfully, and it should therefore be recognized that there is a distinction between having pain and having a problem with pain. Copyright © 2014 John Wiley & Sons, Ltd.
“Zum Wohl der Menschheit”
Authors: Männig Detlef 
Published: December 2014

Abstract100 Jahre nach dem erstmaligen Einsatz von Chemiewaffen im Ersten Weltkrieg sind chemische Kampfstoffe heute weltweit geächtet. Das seit dem Jahr 1997 geltende Chemiewaffenübereinkommen wurde zur Erfolgsgeschichte.
Wenn Nanogramm das Aroma verändern
Authors: Schmarr Hans‐Georg , Slabizki Petra , Legrum Charlotte , Langen Johannes 
Published: December 2014

AbstractOft sind es nur Spuren von Substanzen, die den Charakter eines Weines ausmachen. Diese unter der Menge an flüchtigen Substanzen in einem Weinaroma herauszufinden und zu quantifizieren, erfordert mehrdimensionale chromatographische Trennmethoden und kriminalistischen Spürsinn.