bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multisource information fusion method for vegetable disease detection
Authors: Liu Jun , Wang Xuewei 
Published: August 2024

AbstractAutomated detection and identification of vegetable diseases can enhance vegetable quality and increase profits. Images of greenhouse-grown vegetable diseases often feature complex backgrounds, a diverse array of diseases, and subtle symptomatic differences. Previous studies have grappled with accurately pinpointing lesion positions and quantifying infection degrees, resulting in overall low recognition rates. To tackle the challenges posed by insufficient validation datasets and low detection and recognition rates, this study capitalizes on the geographical advantage of Shouguang, renowned as the “Vegetable Town,” to establish a self-built vegetable base for data collection and validation experiments. Concentrating on a broad spectrum of fruit and vegetable crops afflicted with various diseases, we conducted on-site collection of greenhouse disease images, compiled a large-scale dataset, and introduced the Space-Time Fusion Attention Network (STFAN). STFAN integrates multi-source information on vegetable disease occurrences, bolstering the model’s resilience. Additionally, we proposed the Multilayer Encoder-Decoder Feature Fusion Network (MEDFFN) to counteract feature disappearance in deep convolutional blocks, complemented by the Boundary Structure Loss function to guide the model in acquiring more detailed and accurate boundary information. By devising a detection and recognition model that extracts high-resolution feature representations from multiple sources, precise disease detection and identification were achieved. This study offers technical backing for the holistic prevention and control of vegetable diseases, thereby advancing smart agriculture. Results indicate that, on our self-built VDGE dataset, compared to YOLOv7-tiny, YOLOv8n, and YOLOv9, the proposed model (Multisource Information Fusion Method for Vegetable Disease Detection, MIFV) has improved mAP by 3.43%, 3.02%, and 2.15%, respectively, showcasing significant performance advantages. The MIFV model parameters stand at 39.07 M, with a computational complexity of 108.92 GFLOPS, highlighting outstanding real-time performance and detection accuracy compared to mainstream algorithms. This research suggests that the proposed MIFV model can swiftly and accurately detect and identify vegetable diseases in greenhouse environments at a reduced cost.
Potentially inappropriate prescribing (PIP) in older people and its association with socioeconomic deprivation—a systematic review and narrative synthesis
Authors: Hire Adrian James , Franklin Bryony Dean 
Published: August 2024

Abstract
Background
Potentially inappropriate prescribing (PIP) refers to the prescription of medications that carry a higher risk of adverse outcomes, such as drug interactions, falls, and cognitive impairment. PIP is of particular concern in older adults, and is associated with increased morbidity, mortality, and healthcare costs. Socioeconomic deprivation has been identified as a potential risk factor for PIP. However, the extent of this relationship remains unclear. This review aimed to synthesize the current literature on the association between PIP and socioeconomic status (SES) in older adults.

Methods
A literature search was conducted using the databases Medline, Embase and CINAHL. A search strategy was developed to capture papers examining three key concepts: PIP, socioeconomic deprivation and older/elderly populations. Peer-reviewed quantitative research published between 1/1/2000 and 31/12/2022 was eligible for inclusion.

Results
Twenty articles from 3,966 hits met the inclusion criteria. The sample size of included studies ranged from 668 to 16.5million individuals, with the majority from Europe (n = 8) and North America (n = 8). Most defined older patients as being 65 or over (n = 12) and used income (n = 7) or subsidy eligibility (n = 5) to assess SES. In all, twelve studies reported a statistically significant association between socioeconomic deprivation and an increased likelihood of experiencing PIP. Several of these reported some association after adjusting for number of drugs taken, or the presence of polypharmacy. The underlying reasons for the association are unclear, although one study found that the association between deprivation and higher PIP prevalence could not be explained by poorer access to healthcare facilities or practitioners.

Conclusion
The findings suggest some association between an older person’s SES and their likelihood of being exposed to PIP. SES appears to be one of several factors that act independently and in concert to influence an older person’s likelihood of experiencing PIP. This review highlights that prioritising older people living in socioeconomically-deprived circumstances may be an efficient strategy when carrying out medication reviews.
Exercise, mental well-being and burnout in Thai medical students in 2020–2021: an online cross-sectional survey
Authors: Dhachpramuk Dhachdanai , Sonjaipanich Suprapath , Theppiban Supparat , In-iw Supinya 
Published: August 2024

Abstract
Introduction
Within the Thai medical curriculum, its rigorous education framework, demanding schedules and high academic standards can contribute to psychological distress. Regular physical activity has consistently shown positive effects on mental health. The aim of the study was to investigate the association between exercise and psychological well-being, including depression, anxiety, and burnout, in Thai medical students, and factors related to insufficient exercise and depression.

Methods
The cross-sectional study was conducted among medical students in the university hospital during 2020–2021. Participants completed self-administered questionnaires consisting of demographic data, Godin-Shephard Leisure-Time Physical Activity Questionnaire, depression screening (9Q), Thai General Health Question-28 (4 domains: somatic symptoms, anxiety and insomnia, social dysfunction, severe depression), and Maslach burnout inventory (Emotional exhaustion (EE), Depersonalization (DP), Reduced Personal Achievement (rPA).

Results
Of the 404 participants, 50.5% were women, the mean age (SD) was 21.06 (1.8) years, and 52% were in clinical years. The prevalence of insufficient exercise was 59.6%, depression (30.2%), somatic symptoms (27.7%), anxiety (30.7%), insomnia (89.4%), social dysfunction (89.4%), high level of EE (32.4%), DP (21%), and rPA (56.7%). Insufficient exercise was associated with moderate to severe depression (OR 2.89, 95% CI 1.16–7.25), anxiety and insomnia (OR 1.56, 95% CI 1.01–2.43), social dysfunction (OR 2.51, 95% CI 1.31–4.78), burnout in part due to high rPA (OR 2.4, 95% CI 1.4–4.13), and study in clinical years (OR 1.91, 95% CI 1.28–2.87). After adjusted significant factors, only studying in the clinical year, social dysfunction, and burnout in part of rPA were related to insufficient exercise.

Conclusions
High rates of insufficient exercise, psychological challenges, and burnout were prevalent among medical students. To effectively address these issues, medical school should advise students to participate in regular exercise, promoting mental well-being and healthier lifestyles.
Towards an integrative approach of healthcare: implementing positive health in three cases in the Netherlands
Authors: de Bekker Ankie , Beijer Maarten , Lemmens Lidwien 
Published: August 2024

Abstract
Background
The healthcare system is under tremendous pressure. One possible solution towards relieving some of this pressure is to use Positive Health, which takes ‘health’ as a starting point, rather than ‘illness’. Positive Health provides opportunities for stimulating integrated care.

Methods
Three cases in the Netherlands are studied in this paper. Their way of working with Positive Health is investigated through semi-structured and narrative interviews, using realist-evaluation and thematic analyses.

Results
Seven ‘working elements’ are identified that enhance the chances of successfully implementing Positive Health in practice (part 1). The interviews show that healthcare professionals have noticed that people adopt a healthier lifestyle and gain a greater degree of control over their own health. This boosts job satisfaction for healthcare professionals too. The organisations and professionals involved are enthusiastic about working with Positive Health, but still experience barriers (part 2).

Conclusions
The results of this study imply that implementing Positive Health in practice can facilitate collaboration between organisations and professionals from different disciplines, such as healthcare, welfare, and municipal health services. Operating from the perspective of a shared goal, professionals from different disciplines will find it easier to jointly organise activities to foster citizens’ health. Additionally, more attention is paid to non-medical problems affecting people’s well-being, such as loneliness or financial problems.
India Hypertension Control Initiative: decentralization of hypertension care to health wellness centres in Punjab and Maharashtra, India, 2018–2022
Authors: Chavan Tejpalsinh A. , Kaviprawin Mogan , Sakthivel Manikandanesan , Kishore Navneet , Jogewar Padmaja , Gill Sandeep Singh , Kunwar Abhishek , Durgad Kiran , Wankhede Amol B. , Bharadwaj Vishwajit , Khedkar Suhas N. , Sarode Lalit , Das Bidisha , Bangar Sampada D. , Venkatasamy Vettrichelvan , Gupta Ashu , Kriina Mosoniro , Krishna Ashish , Pathni Anupam Khungar , Sahoo Swagata K. , Parasuraman Ganeshkumar , Shivashankar Roopa , Pragya Pragati , Sharma Meenakshi , Kaur Prabhdeep 
Published: August 2024

Abstract
Introduction
The India Hypertension Control Initiative (IHCI) emphasizes decentralized patient-centric care to boost hypertension control in public healthcare facilities. We documented the decentralization process, enrolment pattern by facility type, and treatment outcomes in nine districts of Punjab and Maharashtra states, India, from 2018–2022.

Methods
We detailed the shift in hypertension care from higher facilities to Health and Wellness Centres (HWCs) using the World Health Organization (WHO) health system pillar framework. We reviewed hypertension treatment records in 4,045 public facilities from nine districts in the two states, focusing on indicators including registration numbers, the proportion of controlled, uncontrolled blood pressure (BP), and missed visits among those under care.

Results
The decentralization process involved training, treatment protocol provision, supervision, and monitoring. Among 394,038 individuals registered with hypertension from 2018–2021, 69% were under care in 2022. Nearly half of those under care (129,720/273,355) received treatment from HWCs in 2022. Care of hypertensive individuals from district hospitals (14%), community health centres (20%), and primary health centres (24%) were decentralized to HWCs. Overall BP control rose from 20% (4,004/20,347) in 2019 to 58% (157,595/273,355) in 2022, while missed visits decreased from 61% (12,394/20,347) in 2019 to 26% (70,894/273,355) in 2022. This trend was consistent in both states. HWCs exhibited the highest BP control and the lowest missed visits throughout the study period compared to other facility types.

Conclusion
We documented an increase in decentralized access to hypertension treatment and improved treatment outcomes over four years. We recommend operationalizing hypertension care at HWCs to other districts in India to improve BP control.
Validity and reliability of self-reported methods for assessment of 24-h movement behaviours: a systematic review
Authors: Šuc Anja , Einfalt Lea , Šarabon Nejc , Kastelic Kaja 
Published: August 2024

Abstract
Background
Time spent in sleep, sedentary behaviour (SB), and physical activity are exhaustive and mutually exclusive parts of a 24-h day that need to be considered in a combination. The aim of this study was to identify validated self-reported tools for assessment of movement behaviours across the whole 24-h day, and to review their attributes and measurement properties.

Methods
The databases PubMed, Scopus, and SPORTDiscus were searched until September 2023. Inclusion criteria were: (i) published in English language, (ii) per-reviewed paper, (iii) assessment of self-reported time spent in sleep, SB, and physical activity, (iv) evaluation of measurement properties of all estimates across the full 24-h day, and (v) inclusion of adolescents, adults, or older adults. The methodological quality of included studies was assessed using the Consensus-based Standards for the selection of health Measurement Instruments checklist.

Results
Our search returned 2064 records. After studies selection, we included 16 articles that reported construct validity and/or test-retest reliability of 12 unique self-reported tools – eight questionnaires, three time-use recalls, and one time-use diary. Most tools enable assessment of time spent in sleep, and domain-specific SB and physical activity, and account that sum of behaviours should be 24 h. Validity (and reliability) correlation coefficients for sleep ranged between 0.22 and 0.69 (0.41 and 0.92), for SB between 0.06 and 0.57 (0.33 and 0.91), for light-intensity physical activity between 0.18 and 0.46 (0.55 and 0.94), and for moderate- to vigorous-intensity physical activity between 0.38 and 0.56 (0.59 and 0.94). The quality of included studies being mostly fair-to-good.

Conclusions
This review found that only a limited number of validated self-reported tools for assessment of 24-h movement behaviours are currently available. Validity and reliability of most tools are generally adequate to be used in epidemiological studies and population surveillance, while little is known about adequacy for individual level assessments and responsiveness to behavioural change. To further support research, policy, and practice, there is a need to develop new tools that resonate with the emerging 24-h movement paradigm and to evaluate measurement properties by using compositional data analysis.

Systematic review registration
PROSPERO CRD42022330868.
Primary pulmonary meningioma presenting as a pulmonary ground glass nodule: a case report and review of the literature
Authors: Zhao Shengliang , Liu Xiaoqing , Xiang Mingzhang , Dai Jigang 
Published: August 2024

Abstract
Background
A primary pulmonary meningioma is an extremely rare entity. Primary pulmonary meningiomas manifested with a ground glass nodule are a very rare occurrence in clinical practice.

Case presentation
In this study, we report a case of a primary pulmonary meningioma with atypical computed tomography features. A 59-year-old Han Chinese female came to our hospital for treatment and reported that her physical examination revealed a ground glass nodule in the right lung for over 3 months. The histologic result revealed a primary pulmonary meningioma. The patient underwent a thoracoscopic lung wedge resection of the right upper lobe for a ground glass nodule. After 1 year of follow-up, the patient is still alive without evidence of metastasis or recurrence.

Conclusions
Primary pulmonary meningiomas could have a variety of radiological findings. As there are no specific radiologic features for the diagnosis of primary pulmonary meningiomas, complete resection of the lesion is required for both diagnosis and treatment. It is necessary to note the imaging features of primary pulmonary meningiomas, presenting as a ground glass nodule; this rare tumor should be considered in differential diagnoses.
Fast computation of function composition derivatives for flatness-based control of diffusion problems
Authors: Scholz Stephan , Berger Lothar 
Published: August 2024

AbstractThe chain rule is a standard tool in differential calculus to find derivatives of composite functions. Faà di Bruno’s formula is a generalization of the chain rule and states a method to find high-order derivatives. In this contribution, we propose an algorithm based on Faà di Bruno’s formula and Bell polynomials (Bell in Ann Math 29:38–46, 1927; Parks and Krantz in A primer of real analytic functions, 2012) to compute the structure of derivatives of function compositions. The application of our method is showcased using trajectory planning for the heat equation (Laroche et al. in Int J Robust Nonlinear Control 10(8):629–643, 2000).
Food security and large-scale land acquisitions by sovereign wealth funds: a systematic review of the literature from 2012 to 2023
Authors: Blekking Jordan , Aassouli Dalal , Jureidini Ray 
Published: August 2024

AbstractMany countries that have large surplus financial resources but contend with limited land and water resources use large-scale land acquisitions (LSLAs) in foreign countries to ensure national food security and earn long-term returns on their investments. LSLAs can provide positive direct and indirect benefits in countries where investment occurs by increasing access to financial and technical resources. On the other hand, LSLA critics state inequitable and unsustainable resource use practices are common, and that negative impacts tend to disproportionately impact local communities. Using the PRISMA systematic literature review approach, we conducted a literature review of 49 articles published between 2012 and early 2023 to understand if LSLAs contribute to food security, if national sovereign wealth funds invest in LSLAs, and to what extent the environmental, social, and governance impacts of LSLAs are evaluated. We find that most articles in our review state LSLAs do not improve food security in the country where the investment occurs or in the country where the investment originates. We also find that sovereign wealth funds were not prevalent LSLA investors during the study period, despite becoming a top contributor to agri-food sector investments during the same time. Finally, we find that the environmental, social, and governance impacts of LSLAs are not equally considered. Specifically, governance impacts are poorly understood. Improving the governance mechanisms associated with LSLAs could increase the equitability and sustainability of LSLAs, thus ensuring the public’s best interest in the immediate and long-term and reassuring investors about the long-term financial viability of their investment.
Five-Year Follow-Up of Standard-of-Care Axicabtagene Ciloleucel for Large B-Cell Lymphoma: Results From the US Lymphoma CAR T Consortium
Authors: Jain Michael D. , Spiegel Jay Y. , Nastoupil Loretta J. , Tamaresis John , Ghobadi Armin , Lin Yi , Lekakis Lazaros , Reagan Patrick , Oluwole Olalekan , McGuirk Joseph , Deol Abhinav , Dorritie Kathleen A. , Sehgal Alison R. , Goy Andre , Hill Brian T. , Andreadis Charalambos , Munoz Javier , Ulrickson Matthew , Westin Jason , Chavez Julio C. , Patel Dilan , Jacobs Miriam T. , Bansal Radhika , Bennani N. Nora , Patel Vivek G. , Rapoport Aaron P. , Vose Julie M. , Miklos David B. , Neelapu Sattva S. , Locke Frederick L. , Lunning Matthew , Dahiya Saurabh 
Published: August 2024

PURPOSE
Axicabtagene ciloleucel (axi-cel) is an autologous CD19 chimeric antigen receptor (CAR) T-cell therapy that is approved for the treatment of relapsed or refractory large B-cell lymphoma. Little is known about the long-term survivorship after CAR T-cell therapy.

METHODS
We previously reported the results of 298 patients who were leukapheresed with the intent to receive standard-of-care axi-cel (n = 275 infused) after two or more previous lines of therapy at a median follow-up of 12.9 months. Here, we report extended follow-up of this cohort to a median of 58 months, with a focus on late survivorship events.

RESULTS

Among axi-cel–infused patients, progression-free survival at 5 years was 29% and overall survival (OS) at 5 years was 40%. The 5-year lymphoma-specific survival was 53% with infrequent late relapses. However, the 5-year nonrelapse mortality (NRM) was 16.2%, with over half of NRM events occurring beyond 2 years. Patients who were 60 years and older had a lower risk of relapse (
P
= .02), but a higher risk of NRM compared with patients younger than 60 years (NRM odds ratio, 4.5 [95% CI, 2.1 to 10.8];
P
< .001). Late NRM was mainly due to infections and subsequent malignant neoplasms (SMNs). In total, SMNs occurred in 24 patients (9%), including therapy-related myeloid neoplasms (n = 15), solid tumors (n = 7), and unrelated lymphoid malignancies (n = 2).

CONCLUSION
In the standard-of-care setting, axi-cel exhibits outcomes consistent with those reported in clinical trials, with sustained, durable responses observed at the 5-year time point. However, late infections and the development of SMN are key survivorship issues that reduce long-term survival after CAR T-cell therapy, particularly in the elderly.
The effect of in-bed cycling combined with high flow nasal cannula treatment on arterial oxygen and respiratory dynamics in patients with severe respiratory failure: A retrospective study
Authors: Wang Xiaoyan , Zhang Jiapo , Jiang Yang , Liu Jie , Huo Deyuan 
Published: August 2024

Objective: To assess the effects of in-bed cycling (IBC) combined with high flow nasal cannula (HFNC) on arterial oxygen and respiratory dynamics in patients with severe respiratory failure (RF).
Methods: We retrospectively collected clinical data of 103 patients with severe RF, admitted to the intensive care unit (ICU) of The Second Affiliated Hospital of Harbin Medical University from March 2021 to March 2023. Among them, 50 patients had HFNC alone (control group), and 53 patients did IBC in addition to HFNC (observation group). We compared arterial oxygen index, lung function, respiratory dynamics, and clinical efficacy between the two groups.
Results: There was no significant difference in the basic data between the two groups (P>0.05). After the treatment, the improvement of the partial pressure of oxygen (PaO2), PaO2/fraction of inspired oxygen (FiO2), arterial oxygen saturation (SaO2), and oxygen delivery (DO2) in the observation group was significantly better than that in the control group (P<0.05). After the treatment, the improvement of lung function in the observation group was better than that in the control group (P<0.05). After the treatment, the end expiratory pulmonary pressure (Ptp-ee) and driving pressure (△Ptp) levels in the observation group were significantly higher, and the duration of ICU hospitalization and the incidence of ICU-acquired weakness(ICU-AW) were significantly lower than those in the control group (P<0.05).
Conclusions: IBC combined with HFNC can significantly improve arterial oxygen levels, lung function, and respiratory dynamics in patients with severe RF. IBC in combination with HFNC is associated with shorter stay time in the ICU, reduced of ICU-acquired weakness, and better physical recovery of patients.
doi: https://doi.org/10.12669/pjms.40.8.9471
How to cite this: Wang X, Zhang J, Jiang Y, Liu J, Huo D. The effect of in-bed cycling combined with high flow nasal cannula treatment on arterial oxygen and respiratory dynamics in patients with severe respiratory failure: A retrospective study. Pak J Med Sci. 2024;40(8):---------. doi: https://doi.org/10.12669/pjms.40.8.9471
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