bluuebunny/crossref_metadata_2025_split huggingface dataset:
Farmacocinética plasmática de la balofloxacina en terneros
Authors: García Hugo , Prieto Guillermo , Lüders Carlos , Errecalde Carlos 
Published: August 2024

Summary
Pharmacokinetic parameters of absorption and disposition of balofloxacin were determined in female Holando-Argentinean calves (n = 6), after a 5 mg/kg single dose, administered as both intravenous and subcutaneous bolus, in a crossed-over design treatment. The analyte was determined in plasma samples by microbiological method in agar diffusion, using a Bacillus subtilis BGA spore solution as microorganism detector in agar Antibiotic Nº 1. The plasmatic concentrations of balofloxacin based on the time were analyzed by a non compartimental kinetic model using software PK Solution 2.0. The intravenous pharmacokinetic parameters obtained were: t1/2β = 2.3 ± 1.1 h; Cltotal area = 10.2 ± 3.4 ml/min/kg; Vdarea = 1.8 ± 0.3 L/kg; and AUCarea = 551.3 ± 247.0 µg/min/ml. Except for Cltotal area and AUCarea, the values obtained for the intravenous administration significantly differed from the obtained ones for the subcutaneous route (p < 0.05), for which Cmax = 1.3 ± 0.4 µg/ml, tmax = 51 ± 12.1 minutes and bioavailability values close to 98% were obtained. The Vdarea value was superior to 1 l/kg for both routes of application and indicates good capacity to spread to extravascular area and tissues.
AUTOCRATIZAÇÃO E ENFRAQUECIMENTO DA DEMOCRACIA NO BRASIL: 2019-2022
Authors: Witt Bendlin Rafaela , Witt Cleonice 
Published: August 2024

O desafio mundial contemporâneo é assegurar a proteção aos direitos humanos fundamentais e a democracia. Mas pesquisas atuais demonstram que há uma grande onda autocrática no mundo, colocando cada vez mais países e cidadãos em risco. Assim, neste contexto, buscou-se compreender a realidade brasileira da autocratização, questionando-se qual foi a evolução da autocracia no Brasil entre os anos de 2019 a 2022? Para responder esta pergunta, buscou-se definir autocracia e democracia, explanar o avanço da autocracia no Brasil a partir de 2019, identificar fatores que favorecem o avanço da autocracia e delimitar o contexto político brasileiro no avanço da autocracia. A metodologia empregada foi a revisão narrativa através do método bibliográfico, utilizando-se artigos científicos, livros, monografias, dissertações, entre outros, bem como pesquisa estatística realizada pelo V-Dem Institute, e a conclusão foi obtida pelo método dedutivo. Concluiu-se então que o Brasil passou por uma onda crescente de autocratização e enfraquecimentos das características democráticas, especialmente a partir da eleição de Bolsonaro em 2018, mas obtendo melhora destas características com a vitória de Lula nas eleições de 2022. Entretanto, ainda deve permanecer o alerta em defesa da democracia.
Shallow Faulting and Folding beneath South-Central Seattle, Washington State, from Land-Based High-Resolution Seismic-Reflection Imaging
Authors: Stephenson William J. , Odum Jack K. , Pratt Thomas L. 
Published: August 2024

Abstract
The geologic framework of the Seattle fault zone (SFZ) has been extensively studied, but the structure and fault strand locations in the central portion of the fault zone through the city of Seattle have remained controversial. Much of what is known about the SFZ has come from light detection and ranging (lidar)-topographic surveys and paleoseismic investigations of fault scarps primarily west of Puget Sound, regional gravity and aeromagnetic modeling, and multiscale marine seismic imaging in waters both west and east of Seattle. We analyze ∼24 km of land-based P-wave seismic-reflection data that fill in a critical gap in our understanding of the SFZ beneath the urban areas of West Seattle, south-central Seattle, and Mercer Island. These data image deformed strata in the upper 1 km, including upwarped Tertiary rock and younger sediments. Collectively, these data provide evidence for multiple Quaternary-active thrust faults, back thrusts, and sub-basins within the SFZ beneath the city of Seattle. The results indicate that multiple and potentially active back thrusts in the upper ∼500 m extend across the length of the SFZ and the entire urban corridor that may be analogous to those on Bainbridge Island west of Puget Sound.
FISICA Y COSMOLOGIA DE LA RADIACION COSMICA DE FONDO
Authors: Torres Arzayúz Sergio 
Published: August 2024

En la radiación cósmica de fondo (RCF) está impresa la información acerca de las condi­ciones existentes en el universo temprano. Mediciones precisas en un rango adecuado de esca­las angulares y frecuencias de la RFC harán posible encontrar de forma definitiva los más importantes parámetros cosmológicos: curvatura, constante cosmológica y forma del espectro de fluctuaciones primordiales. El satélite COBE ha permitido avanzar considerablemente en esta tarea con las mediciones de anisotropías a escalas angulares ≥7°. Se hace una introducción a la teoría de la RCF, se presentan los resultados más recientes obtenidos por COBE y se hace una prueba de modelos cosmológicos abiertos y con constante cosmológica usando los mapas de anisotropía del instrumento DMR a bordo de COBE. El resultado de este análisis revela que los datos son consistentes con modelos abiertos favoreciendo un valor del parámetro de densidad Ω=0.8. Los datos también permiten valores no nulos para la constante cosmológica.
Behcet’s disease: a clinical case of how one uncommon disease was misdiagnosed as another uncommon disease
Authors: Manto I. A. , Shigina E. A. 
Published: August 2024

Bechet’s disease is a rare, multifactorial, systemic inflammatory disease of unknown etiology. Oral and genital ulcers, uveitis, and cutaneous lesions (pseudofolliculitis and erythema nodosum) are its most common manifestations. Less frequent manifestations include lesions of the cardiovascular, joint, gastrointestinal, and nervous systems. There are no specific diagnostic tests for Bechet’s, and the diagnosis is eatablished based on revealed clinical criteria. Due to the variability in clinical presentation, the predominance of non-rheumatic symptoms, and the lack of awareness among physicians, there is often a delay in diagnosis. This can lead to misdiagnosis and unnecessary treatment for patients.This article presents a clinical case of Bechet’s disease, which was initially diagnosed as primary immunodeficiency.
Pengaruh <i>Store Atmosphere</i> dan <i>Price</i> terhadap <i>Customer Loyalty </i>yang Dimediasi <i>Customer Satisfaction</i> di Transmart Bandung dan Cimahi
Authors: Ni Komang Prastiti Dewi  , Hariyadi Triwahyu Putra  
Published: August 2024

Penelitian ini bertujuan untuk menganalisis pengaruh Store Atmoshphere dan Price terhadap Customer Loyalty dimediasi Customer Satisfaction di Transmart Bandung dan Cimahi. Penelitian ini menggunakan metode kuantitatif. Setelah pengumpulan data melalui survei kuesioner, dilakukan pengolahan data dengan teknik analisis regresi berganda dengan menggunakan alat Statistical Program for Social Sciences (SPSS) versi 29 untuk melakukan analisis deskriptif dan tervalidasi. Selanjutnya kami menjalankan tes Sobel menggunakan kalkulator Sobel. Hasil menemukan bahwa Store Atmosphere mempunyai hubungan yang positif dan signifikan terhadap Customer satisfaction, Price mempunyai hubungan yang positif dan signifikan terhadap Customer satisfaction, Store Atmosphere mempunyai hubungan yang negatif dan tidak signifikan terhadap Customer loyalty, Price mempunyai hubungan yang positif dan signifikan terhadap Customer loyalty, Customer satisfaction mempunyai hubungan yang positif dan signifikan terhadap Customer loyalty, Store Atmosphere terhadap Customer loyalty mempunyai hubungan yang positif dan signifikan melalui Customer satisfaction, Price terhadap Customer loyalty mempunyai hubungan yang positif dan signifikansi melalui melalui Customer satisfaction.
PRÁTICAS COMUNITÁRIAS ENTRE INTERIOR E CENTRO
Authors: Sbardelotto Diane , Gruppelli Loponte Luciana 
Published: August 2024

A partir de práticas artísticas comunitárias realizadas em locais do interior, esse artigo busca pensar modos de promover processos decoloniais na formação docente em Artes Visuais. Ações e obras dos coletivos Inço e Adentro, além do projeto Una Escuela Sustentable, as quais deslocam noções colonizadas de arte, atuando de modo comunitário e fora de centros de poder, são pensadas quanto às suas contribuições para a docência em artes visuais. Tais exemplos podem expandir as concepções de arte para além das noções da história universal da arte, por meio de poéticas coletivas e situadas. Ensinam também que a sustentabilidade nos territórios deve considerar a simultaneidade entre a valorização local e a crítica das heranças coloniais.
Analisis Faktor-Faktor yang Mempengaruhi Pengungkapan Emisi Karbon pada Perusahaan BUMN
Authors: Lasmiati  , Pahala Indra , Khairunnisa Hera 
Published: August 2024

Penelitian ini bertujuan untuk menganalisis pengaruh ukuran perusahaan, kinerja lingkungan, profitabilitas dan Leverage terhadap pengungkapan emisi karbon pada perusahaan Badan Usaha Milik Negara (BUMN). Tingkat pengungkapan emisi karbon diukur dengan menggunakan checklist carbon emission disclosure. Penelitian menggunakan data sekunder yang bersumber dari laporan keuangan, laporan keberlanjutan dan laporan peringkat PROPER dari perusahaan BUMN yang terdaftar di Bursa Efek Indonesia (BEI) serta berpartisipasi pada program PROPER selama tahun 2016-2022. Sebanyak 98 sampel observasi terpilih melalui teknik purposive sampling yang diolah dengan analisis regresi data panel menggunakan Eviews 12. Berdasarkan hasil penelitian ditemukan adanya pengaruh positif ukuran perusahaan terhadap pengungkapan emisi karbon, sementara Leverage ditemukan memiliki pengaruh negatif terhadap pengungkapan emisi karbon. Namun, kinerja lingkungan dan profitabilitas tidak secara signifikan memiliki pengaruh terhadap pengungkapan emisi karbon.

Kata Kunci: Pengungkapan Emisi Karbon, Ukuran Perusahaan, Kinerja Lingkungan, Profitabilitas, Leverage
Bilateral Patellar Brown Tumors as Presenting Symptom of Hyperparathyroidism
Authors: Meinerz Carolyn , Wooldridge Adam , King David 
Published: August 2024

Case:
Osteolytic lesions have a broad differential. We present a 33-year-old man with bilateral patellar lytic lesions with unilateral pathologic fracture. Workup demonstrated hyperparathyroidism and isolated patellar lesions consistent with brown tumors. The patient underwent subtotal parathyroidectomy followed by curettage and cement augmentation with open reduction internal fixation of pathologic fracture and aspiration with injection of Pro-Dense to unfractured side. The patient is 2 years postoperatively and doing well.

Conclusion:
Multiple lytic lesions in bone should raise concern for possible metabolic derangements as the cause. Workup for brown tumors including hyperparathyroidism laboratory markers is an important differential diagnosis for orthopaedic surgeons.
Mesenteric lymph nodes involvement in advanced ovarian cancer patients after debulking surgery
Authors: CANDOTTI GIORGIO , PEIRETTI MICHELE , BERGAMINI ALICE , GALLI FEDERICA , FAIS MARIA LUISA , CIOFFI RAFFAELLA , RABAIOTTI EMANUELA , MANGILI GIORGIA , CANDIANI MASSIMO , BOCCIOLONE LUCA 
Published: August 2024

Abstract

Purpose: In literature only few studies investigated the role of mesenteric lymph nodes in the context of bowel resection during cytoreductive surgery for ovarian cancer (OC). Despite the lack of a consensus regarding the best surgical approach, data showed connection between depth of bowel infiltration, rectosigmoid lymph-vascular space infiltration with mesenteric lymph nodes involvement. This study investigates the incidence of mesenteric lymph nodes involvement in patients undergoing bowel resection during debulking surgery in advanced OC and its correlation with pathological factors.
Methods: This is a retrospective study collecting data from November 2018 to August 2022 in two Italian Institutions (IRCCS San Raffaele Hospital, Vita e Salute University Milan and Policlinico Monserrato, University of Cagliari). OC patients undergoing rectosigmoid resection during primary debulking surgery or interval debulking surgery were recorded. The characteristics of mesenteric node involvement were evaluated.
Results: Mesenteric lymph nodes were detected in 38/67 cases (57%); involvement rate was 53%. Metastatic mesenteric lymph nodes were associated with depth of bowel infiltration (p = 0.009). Significant correlation between positive mesenteric lymph nodes and pelvic lymph nodes (p = 0.022), aortic lymph nodes (p = 0.005) was found. No association was found between mesenteric lymph nodes involvement and pattern of relapse. BRCA status did not affect mesenteric lymph nodes involvement.
Conclusion: OC patients undergoing rectosigmoid resection during debulking surgery revealed metastatic mesenteric lymph nodes involvement in 53% of cases. This finding was related to a deeper infiltration of the bowel, rectosigmoid lymph-vascular space infiltration, pelvic and aortic lymph nodes metastases.
Application of single venous approach under echocardiographic without angiography in closure of Patent Ductus Arteriosus
Authors: Xiong Pan , Chen Quan , He Yiwei 
Published: August 2024

Abstract

Background: The conventional arteriovenous approach closure of patent ductus arteriosus（PDA）may be associated with more complications especially in young infants. The objective is to explore the feasibility and clinical efficacy of interventional closure of PDA through single venous approach under echocardiographic without angiography.
Methods: 112 patients (32 males and 80 females) with PDA closed by different methods in Suining Central Hospital were enrolled, including 60 cases with single venous approach under echocardiographic without angiography and 52 cases with conventional arteriovenous approach. There were no significant differences in age and gender composition between the two groups. The success rate of operation, complete closure rate of 24 hours,Procedure time, X-ray fluoroscopic time, radiation dose, intraoperative contrast volume, preoperative and postoperative creatinine, preoperative and postoperative uric acid nitrogen, bed rest time, total hospital stay and incidence of vascular complications were compared between the two groups.
Results: There were no significant differences in the success rate of operation (100% vs 100%) and the complete closure rate of 24 hours (100% vs 100%) between the two groups (P>0.05). In the single venous approach group, the Procedure time was (50.05±4.78min vs 57.69±6.44min), the X-ray fluoroscopy time was (7.30±0.78min vs 10.23±1.58min), and the radiation dose was (79.57±15.18mGy vs 219.22±34.60mGy), contrast volume (0mL vs 62.22±22.69ml), bed rest time (4.03±0.99h vs 12.25±1.73h), total hospital stay (3.30±0.52 days vs 3.39±0.49 days) and the incidence of vascular complications (0% vs 13.9%) were significantly lower than those in the traditional angiography group (P<0.05). There were no significant changes in creatinine (51.86±12.75umol/L vs 53.09±10.27umol/L) and urea nitrogen (4.81±1.21mmol/L vs 4.98±0.93mmol/L) before and after operation in single venous group (P>0.05). Compared with preoperative creatinine level (68.23±8.66umol vs 59.23±22.12umol) and urea nitrogen level (5.98±1.13mmol/L vs 5.16±1.49mmol/L) in traditional angiography group after operation (24 hours) were significantly increased (P < 0.05).
Conclusions: Compared with the conventional arteriovenous approach, the single venous approach has the outstanding advantage of reducing vascular complications, contrast volume, radiation dose,procedure time .Compared with the conventional arteriovenous approach, on the basis of obtaining the same efficacy, the PDA occlusion of the single venous approach under echocardiographic without angiography has the outstanding advantages of simplified operation, less X-ray radiation, no contrast agent injury, short bed rest time, and fewer vascular complications.It is a green and safe surgical method worth promoting for PDA patients with suitable anatomical conditions.
Research on Deduction of Social Media Public Opinion Based on UCIGR Model
Authors: Song Jinbao , Sun Xiangyu 
Published: August 2024

Abstract

As the number of Internet users grows, Internet public opinion spreads rapidly on social media, presenting significant challenges for government and related agencies in managing public sentiment. In light of this, it is crucial to propose a public opinion deduction method that aligns with the current era. This paper combines communication dynamics research with real-world observation and analysis of public opinion communication processes. Building upon the UCIR model, the study introduces the UCIGR (unknown-contact-infective-guided-recovered) communication model, incorporating the instructor-accepted state into the model. The model establishes a law of secondary propagation of public opinion based on this state. Compared to the UCIR model, the UCIGR model proposed in this research demonstrates a 27% improvement in performance, offering a more realistic restoration of the dissemination process of public opinion information. Furthermore, leveraging the rules of the UCIGR model, the study deduces and analyzes public opinion from two dimensions, providing a new framework for governments and related institutions to formulate effective public opinion guidance strategies.
Optimizing groundwater management to prevent drawdown and sustain agricultural production using machine learning model
Authors: Wang Sheng-Wei , Kao Yu-Hsuan , Chen Yen-Yu , Hsu Shu-Han , Kimura Masaomi , Chang Li-Chiu , Pan Tzi-Wen 
Published: August 2024

Abstract

This study presents a comprehensive analysis of groundwater level prediction and management using an extreme gradient boosting (XGB) model, optimized through Bayesian techniques. To address the challenge of unavailable accurate pumping volume data in high-density agricultural well areas, our approach leverages well power consumption as a key feature for the machine learning model. This innovative method enables accurate groundwater level predictions based on precipitation and power consumption data. To mitigate significant groundwater level declines during drought periods, the developed XGB model offers flexible design scenarios with varying degrees of groundwater extraction reduction. This capability allows for rapid predictions of groundwater levels, providing decision-makers with a powerful tool to adapt to hydrological uncertainties caused by future climate change. The results of model testing present that the increases in groundwater levels with a 25% reduction in power consumption range from 0.45 to 0.79 m during the wet season and from 0.45 to 0.99 m during the dry season. Interestingly, as the percentage of power consumption reduction increases, the elevations in groundwater levels do not increase proportionally, indicating that the non-linear characteristics among the interactions of precipitation, pumping behaviors, and groundwater level variations. In all three scenarios, the increases in groundwater levels during the dry season are significantly greater than those during the wet season. This implies that appropriate reductions in pumping volumes during drought periods can effectively prevent sharp groundwater level drawdowns. Furthermore, the XGB model plays a crucial role in formulating groundwater extraction reduction policies and agricultural fallow subsidy programs. When considering the opportunity cost of agricultural labor, the subsidies for the first and second crop periods meet only 30% and 59% of the economic profit, respectively. This economic shortfall is a major barrier to the adoption of fallowing practices by farmers during droughts. Therefore, it is crucial to enhance these subsidies to make fallowing a more viable and attractive option for farmers. In conclusion, while predictive modeling offers a robust tool for groundwater management and policy decision-making, there is a clear need for improved economic incentives and integrated management strategies.
Investigation of Climate Extremes in Jabalpur District of Madhya Pradesh: Trends and Future Implications
Authors: Thakur Pankaj Kumar , Gururani Dheeraj Mohan , Agrawal Abhishek , Varade Divyesh , Dubey Snehil , Kumari Pushpanjali 
Published: August 2024

Abstract

Climate change is a long-term change in hydro-meteorological conditions in a particular geographical region. In the present study, spatio-temporal long-term change in rainfall during 1961–2020 was analyzed using IMD 0.25°×0.25° resolution gridded dataset in the Jabalpur district. The non-parametric Mann–Kendall trend test and Sen’s slope estimator was applied to determine the trend and its magnitude, respectively in the precipitation time series. Extreme indices were employed to understand the risks and vulnerabilities associated with extreme weather events in the district. Mann-Kendall trend test showed an insignificant trend at 95% confidence interval with Sen’s slope value of -2.98 to 0.73 mm/year. CLIMPACT tool was used to study extreme indices and it revealed that, in the district, CDD, CWD, R10, R20, and RX5 were decreasing, whereas RX1 and SDII were found increasing. The study’s outcomes provide valuable inferences for future water resource planning and management in central India, particularly in Jabalpur district.
Alkaline-Enhanced Boehmite Catalysts for Catalytic Hydrolysis of Carbonyl Sulfide at Low Temperature
Authors: Lin Jia Yin , Wang Chih-Ying , Lee Jia-Yu 
Published: August 2024

Abstract

The removal of carbonyl sulfide (COS), a byproduct gas in the steel industry, is crucial due to its environmental impact, including acid rain formation and corrosion of chemical equipment. This study explores enhancing the catalytic performance for COS hydrolysis at low temperatures by loading potassium hydroxide (KOH) onto boehmite catalysts. The modified catalysts demonstrated significantly improved COS conversion rates and hydrogen sulfide (H2S) yields compared to untreated counterparts. At 40°C, K/Boehmite catalysts achieved approximately 80% COS conversion. As the temperature increased to 50°C, 60°C, and 70°C, COS conversion rates neared 100%, with H2S yields reaching up to 98% for K/Boehmite-3. Characterization results confirmed that KOH increased the number of active sites on the catalyst surface, enhancing COS adsorption and reaction. The KOH modification increases alkalinity and promotes the formation of surface hydroxyl groups, which play a key role in the hydrolysis reaction. These hydroxyl groups facilitate water adsorption and the breakdown of COS into H2S and CO2. This study presents a straightforward method for KOH impregnation on boehmite, marking the first use of boehmite as a COS hydrolysis catalyst, significantly boosting its efficiency and offering a viable solution for industrial COS removal while effectively generating H2S.