bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of nonpermanent inferior vena cava filter placement in patients with deep venous thrombosis after lower extremity fracture: A single-center retrospective study
Authors: Pan Ye , Zhao Jun , Mei Jiacai , Shao Mingzhe , Zhang Jian , Wu Haisheng 
Published: August 2015

Objective To investigate nonpermanent inferior vena cava (IVC) filter in the prevention of perioperative pulmonary embolism (PE) in patients of lower extremity and/or pelvic bone fracture with deep vein thrombosis (DVT). Methods Lower extremity or pelvic bone fracture patients with lower extremity DVT hospitalized in our hospital from January 2003 to October 2014 were retrospectively analyzed. Data was analyzed for age, gender, position of fracture, position of proximal of thrombosis, indications of placement, complications, retrieval rate, and rate of entrapped filter clot. Patients who underwent IVC filter placement were selected as the filter group. The patients who did not perform IVC filter placement after 2008 and the cases between January 2003 and December 2007 were selected as control group 1 and control group 2, respectively. The incidence of perioperative symptomatic PE and mortality were analyzed. Results A total of 2763 cases complicated with DVT underwent orthopedic surgery between January 2003 and October 2014. 823 nonpermanent filters were inserted. All filters were successfully deployed with no major complications. After a mean 14.2 days indwelling time, all of temporary filters were removed. Retrieval was attempted in 556 patients with retrievable filters and was successful in 545 (98%); mean indwelling time was 16.3 days. The total retrieval rate was 90%. The incidence of PE in the filter group was significantly lower compared with the two control groups. Among the patients who received chemical anticoagulant therapy, the incidence of PE in filter group, control group 1 and control group 2 were 0.14%, 1.60% and 2.10%, respectively. The incidence of PE in filter group was also significant lower compared with control groups. Conclusion Nonpermanent IVC filter placement seems like to be a safe and effective method for preventing perioperative symptomatic and fatal PE in bone fracture patients with DVT in the present retrospective study.
Serum level of proximal renal tubular epithelial cell-binding immunoglobulin G in patients with lupus nephritis
Authors: Yap D Y H , Yung S , Zhang Q , Tang C , Chan T M 
Published: August 2015

In vitro data showed that immunoglobulin G (IgG) from lupus nephritis (LN) patients could bind to proximal renal tubular epithelial cells (PTEC), but the clinical relevance of such binding remained unclear. Binding of IgG and subclasses to PTEC was measured by cellular ELISA (expressed as OD index) in 189 serial serum samples from 23 Class III/IV ± V LN patients who had repeated renal flares (48 during renal flares, 141 during low level disease activity (LLDA)), and compared with 64 patients with non-lupus glomerular diseases (NLGD) and 23 healthy individuals. Total IgG PTEC-binding index was 0.34 ± 0.16, 0.29 ± 0.16, 0.62 ± 0.27 and 0.83 ± 0.38 in healthy controls, NLGD, LN patients during LLDA, and LN patients during nephritic flare, respectively ( p < 0.001, LLDA vs. renal flare; p < 0.001, healthy controls or NLGD vs. LN during LLDA or renal flare). PTEC-binding index for IgG1 was 0.09 ± 0.05, 0.16 ± 0.12, 0.44 ± 0.34 and 0.71 ± 0.46 for the corresponding groups ( p < 0.001, LLDA vs. renal flare; p < 0.001, healthy controls or NLGD vs. LN during LLDA or renal flare). Sixteen of 48 episodes (33.3%) of nephritic flare showed persistent PTEC-binding IgG seropositivity for more than 9.4 ± 3.1 months, despite clinical response to immunosuppressive treatment. Total IgG and IgG1 PTEC-binding correlated with anti-dsDNA level ( r = 0.34 and 0.52, respectively, p < 0.001 for both), and inversely with C3 level ( r = –0.26 and –0.50, respectively, p = 0.002 and<0.001). Sensitivity/specificity of PTEC-binding index in detecting renal flares was 45.8%/80.1% for total IgG (ROC AUC 0.630, p = 0.007) and 87.5%/35.5% for IgG1 (ROC AUC 0.615, p = 0.018). IgG1 PTEC-binding index correlated with tubulo-interstitial inflammation score in renal biopsy from corresponding patients. Our data suggested that total IgG and IgG1 PTEC-binding index in serum of LN patients correlate with serological activity, and in combination could predict renal flares. The correlation between IgG1 PTEC-binding and tubulo-interstitial inflammation suggests potential pathogenetic significance.
Improved glycemic control in veterans with poorly controlled diabetes mellitus using a Specialty Care Access Network-Extension for Community Healthcare Outcomes model at primary care clinics
Authors: Watts Sharon A , Roush Laura , Julius Mary , Sood Ajay 
Published: August 2015

Introduction An increasing number of patients with diabetes mellitus has created a need for innovative delivery of specialized care not only by diabetes specialists but also by primary care providers (PCPs) as well. A potential avenue to address this need is training of PCPs by specialists via telehealth. The Veteran Affairs (VA) Specialty Care Access Network-Extension for Community Healthcare Outcomes (SCAN-ECHO) program includes education and case-based learning for PCPs by a multidisciplinary specialty team utilizing videoconferencing technology. Methods Two PCPs completed a year of SCAN-ECHO diabetes training. These two PCPs set up “diabetes mini-clinics” to treat difficult-to-control high-risk patients with diabetes mellitus from their own panel and from their colleagues in the same community-based outpatient clinic (CBOC). We utilized a retrospective program evaluation by t-test using pre/post glycated hemoglobin (HbA1c) lab values after being seen by the two PCPs. Results A total of 39 patients, all with HbA1c > 9.0%, were seen in the two PCP mini-clinics over 15 months. The mean HbA1c improved from 10.2 ± 1.4% to 8.4 ± 1.8% ( p < 0.001) over the average follow-up period of five months. This was not explained by system-wide changes or improvements. Discussion Care of veteran patients with poorly controlled diabetes by PCPs who participated in SCAN-ECHO program leads to improvement in glycemic control. This model of health care delivery can be effective in remote or rural areas with limited availability of specialists.
Implementation of Endoscopic Submucosal Dissection for Gastric Lesions in Norway
Authors: Rushfeldt C. , Aabakken L. 
Published: August 2015

Background and Aims: Endoscopic submucosal dissection is a minimal invasive method for an en bloc resection of dysplasia or early cancer in the stomach. It was developed in Japan in the 1990s, but thus far has not been widely adopted in Western countries. The aim of this study is to report from the introductory phase of gastric endoscopic submucosal dissection in a small-volume Scandinavian center. Material and Methods: The 15 first patients operated on with endoscopic submucosal dissection in the stomach at the University Hospital of North Norway were consecutively registered in a prospective database and evaluated as a quality assurance study. The indications for the procedures were diagnostic or therapeutic. Results: Three patients had benign lesions, three had low-grade dysplasia, five had high-grade dysplasia, two had neuroendocrine tumors, and two had early gastric cancers (T1b). The R0 resection rate was 83%. One neuroendocrine tumor was directed to surgery. No recurrences have been detected after the median of 6 months, and with the exception of one delayed bleeding being treated endoscopically, no serious complications occurred. Two perforations were perioperatively closed with clips. Conclusion: This is the first report on gastric endoscopic submucosal dissection in Scandinavia. Preliminary results from an introductory phase indicate that endoscopic submucosal dissection for dysplasia or early gastric cancer may be conducted safely and with acceptable results even in a small-volume center, assuming that surgeons and gastroenterologists in a region direct cases to one individual who can learn this skill.
The Role of Mobile Applications in Improving Alcohol Health Literacy in Young Adults With Type 1 Diabetes
Authors: Tamony Peter , Holt Richard , Barnard Katharine 
Published: August 2015

Background: Mobile health (mHealth) is an expanding field which includes the use of social media and mobile applications (apps). Apps are used in diabetes self-management but it is unclear whether these are being used to support safe drinking of alcohol by people with type 1 diabetes (T1DM). Alcohol health literacy is poor among young adults with T1DM despite specific associated risks. Methods: Systematic literature review followed by critical appraisal of commercially available apps. An eSurvey investigating access to mHealth technology, attitudes toward apps for diabetes management and their use to improve alcohol health literacy was completed by participants. Results: Of 315 articles identified in the literature search, 7 met the inclusion criteria. Ten diabetes apps were available, most of which lacked the educational features recommended by clinical guidelines. In all, 27 women and 8 men with T1DM, aged 19-31 years were surveyed. Of them, 32 had access to a smartphone/tablet; 29 used apps; 20 used/had used diabetes apps; 3 had used apps related to alcohol and diabetes; 11 had discussed apps with their health care team; 22 felt more communication with their health care team would increase awareness of alcohol-associated risks. Conclusions: Use of mobile apps is commonplace but the use of apps to support safe drinking in this population was rare. Most participants expressed a preference for direct communication with their health care teams about this subject. Further research is needed to determine the preferences of health care professionals and how they can best support young adults in safe drinking.
Jenseits der Cloud: Metadaten- und Datenmanagement in der bibliothekarischen Infrastruktur
Authors: Altenhöner Reinhard 
Published: August 2015

Zusammenfassung:
In der laufenden Diskussion um die zukünftige Informationsinfrastruktur spielen – auch vor dem Hintergrund einer entsprechenden Förderinitiative der DFG – bibliothekarische Metadaten, ihre Erzeugung und -verwaltung sowie die Träger der entsprechenden Systeme in einem globalen Kontext eine Rolle. Der erste Teil dieses Beitrags versuchte sich an einer Verortung der laufenden Bemühungen einerseits, er beleuchtete aus Sicht des Autors wesentliche Perspektiven und den absehbar erreichbaren Stand. Damit eng verknüpft ist der vorliegende zweite Teil, der sich mit dem Einsatz von Text- und Datamining-Verfahren in Bibliotheken mit einem Schwerpunkt auf den Aktivitäten der Deutschen Nationalbibliothek beschäftigt.
Sequence-specific DNA nicking endonucleases
Authors: Xu Shuang-yong 
Published: August 2015

AbstractA group of small HNH nicking endonucleases (NEases) was discovered recently from phage or prophage genomes that nick double-stranded DNA sites ranging from 3 to 5 bp in the presence of Mg2+ or Mn2+. The cosN site of phage HK97 contains a gp74 nicking site AC↑CGC, which is similar to AC↑CGR (R=A/G) of N.ϕGamma encoded by Bacillus phage Gamma. A minimal nicking domain of 76 amino acid residues from N.ϕGamma could be fused to other DNA binding partners to generate chimeric NEases with new specificities. The biological roles of a few small HNH endonucleases (HNHE, gp74 of HK97, gp37 of ϕSLT, ϕ12 HNHE) have been demonstrated in phage and pathogenicity island DNA packaging. Another group of NEases with 3- to 7-bp specificities are either natural components of restriction systems or engineered from type IIS restriction endonucleases. A phage group I intron-encoded HNH homing endonucleases, I-PfoP3I was found to nick DNA sites of 14–16 bp. I-TslI encoded by T7-like ΦI appeared to nick DNA sites with a 9-bp core sequence. DNA nicking and labeling have been applied to optical mapping to aid genome sequence assembly and detection of large insertion/deletion mutations in genomic DNA of cancer cells. Nicking enzyme-mediated amplification reaction has been applied to rapid diagnostic testing of influenza A and B in clinical setting and for construction of DNA-based Boolean logic gates. The clustered regularly interspaced short palindromic repeats-ribonucleoprotein complex consisting of engineered Cas9 nickases in conjunction with tracerRNA:crRNA or a single-guide RNA have been successfully used in genome modifications.
Semanalysis, Psychoanalysis, and Poststructuralist Feminism
Authors: Festić Fatima 
Published: August 2015

Abstract
Taking the concept of semanalysis as Julia Kristeva’s proposition of a cross-disciplinary work on that which is trans- beneath-, and also beyond the linguistic, it is logical and inevitable to read its psychoanalytic stems, specifically from Sigmund Freud and Jacques Lacan, along with their further dispersal and redirection or utilization in poststructuralist feminism. This article shows how the playing field of these interacting lines re-elucidates Kristeva’s concept of semiotic also as providing with a political dimension the sought out “deeper and hidden meanings”. Further, the article argues that the poststructuralist profiling - Lacan’s semioticizing Freud, Kristeva’s rewriting their common equaling of women with negative/death/lack/void and her further tuning with Helene Cixous and Luce Irigaray, - reveals what semanalysis is about, and what it can lead to. The article also looks for a possible actualization of semanalysis along with Rosi Braidotti's nomadic matter-realist thought.
Dynamics of the Collateral Encyclopedia
Authors: Thellefsen Torkild , Sørensen Bent , Thellefsen Martin 
Published: August 2015

Abstract
Both Umberto Eco and Charles S. Peirce have been concerned with the notion of background knowledge. Eco refers to background knowledge as the encyclopedia; Peirce’s term of reference is collateral experience. The aim of this article is to investigate the degree to which these two concepts are comparable. We focus on one major metaphysical issue, viz. the fact that Eco defines collateral experience, which is the first step in any process of cognition, as private, whereas Peirce, as a realist, would never accept the concept of private thoughts, feelings, etc. We suggest that freeing collateral experience from its nominalistic nomenclature makes possible a comparison and synthesis of Eco’s and Peirce’s conceptions when seen from the perspectives of their cognitive type, nuclear type, and molar content.
A novel and highly efficient polymerization of sulfomethylated alkaline lignins via alkyl chain cross-linking method
Authors: Hong Nanlong , Yu Wei , Xue Yuyuan , Zeng Weimei , Huang Jinhao , Xie Wenqin , Qiu Xueqing , Li Yuan 
Published: August 2015

AbstractA new family of water-soluble lignosulfonate polymers with ultrahigh molecular weight (Mw) was developed based on alkali lignin (AL) as starting material in a one-pot reaction in two steps: sulfomethylation of AL as raw material led to AL-S and this material was subsequently cross-linked via alkylation with 1,6-dibromohexane (alkAL-S). Gel permeation chromatography showed a significant increase of Mw from 5200 Da of AL-S to 201 000 Da of alkAL-S with high degree of alkylation. Fourier transform infrared spectroscopy (FTIR) and proton nuclear magnetic resonance spectroscopy and functional group analysis confirmed the efficient polymerization by a nucleophilic substitution reaction mechanism. Additionally, alkAL-S with high Mw showed unexpected viscosity-reducing effect, stability and good rheological properties on a low-rank coal-water slurry (CWS), which are even better than those obtained by naphthalene sulfonate formaldehyde (NSF) as additive. The adsorption properties of the new products were also characterized via a quartz crystal microbalance combined with dissipation monitoring (QCM-D method). Cross-linked structure, large steric hindrance from high Mw and suitable amphiphilic properties of alkAL-S polymers contribute together to the highly improved dispersion performances for CWS.
Prevalence and correlates of the perpetration of cyberbullying among in-school adolescents in Oyo State, Nigeria
Authors: Olumide Adesola O. , Adams Patricia , Amodu Olukemi K. 
Published: August 2015

Abstract

Objective: Cyberharassment/cyberbullying is a global problem that has been inadequately investigated in developing countries. In this paper, we present findings on the prevalence and predictors of perpetration of cyberbullying among in-school adolescents in Oyo state, Nigeria.

Methods: A total of 653 students were selected via multi-stage sampling. Information on history of perpetrating harassment via an electronic medium in the 3-month period preceding the survey was obtained.

Results: Respondents’ mean age was 14.2±2.2 years and 51.3% were females. All respondents had personal mobile phones and about half had Internet access. About 40% accessed the Internet every day while about 48% accessed it at least once to several times a week and <5% accessed it about once every 2 weeks. One hundred and fifty-six (23.9%) had harassed someone electronically, 260 (39.8%) had been victimized, and 137 (21.0%) were both victims and perpetrators. Common modes of harassment were via phone calls 99 (63.5%), chat rooms 70 (44.9%), and text messages 60 (38.5%). Students who had been victims of cyberbullying (OR=21.76, 95% CI=12.64–37.47) and those with daily Internet access (OR=2.32, 95% CI=1.28–4.19) had significantly higher Oods of being perpetrators.

Conclusion: About a quarter of students were perpetrators of cyberbullying, and the correlates of perpetration were history of cyber victimization and daily Internet access. Intervention programs must be instituted for victims as well as frequent users of the Internet to curb the problem in the study area.
Optical Probe Thermometry Using Optically Trapped Erbium Oxide Nanoparticles
Authors: Johnson Samuel C. , Baral Susil , Alaulamie Arwa A. , Richardson Hugh H. 
Published: August 2015

ABSTRACTA new thermal imaging technique is characterized that uses an optically trapped erbium oxide nanoparticle cluster of approximately 150 nm. This technique can measure absolute temperature and has an imaging spatial resolution of the trapped particle. Scanning optical probe thermometry has been used to thermally image a cluster of gold nanowires that were excited with the trapping laser. Following a deconvolution of the measured thermal profile, a point spread function of the imaging technique has been determined to be a Gaussian with a FWHM of 165 nm. This width is a function of the clustering of Er2O3nanoparticles used to image the nanowire. Optical probe thermometry has further been used to measure the temperature of nucleation events where a dichotomy of temperature for nucleated water occurs from degassed water and native water. Degassed water has been measured to nucleate at 555K confirming water adjacent to the gold nanoparticle superheats to the spinodal decomposition temperature before nucleating into a water vapor bubble. Following this event, the temperature inside the vapor bubble rises to the melting point of the gold nanoparticle, 1300 K which is followed by temperature stabilization. The rapid and significant temperature increase is attributed to the loss of a thermal dissipation pathway, to the surrounding water, previously available to the gold nanoparticle due to the insulator nature of the growing vapor envelope around the gold nanoparticle.
Chitosan-alginate Hybrid Scaffolds for in Vitro Bone Tissue Regeneration
Authors: Li Zhensheng , Ramay Hassna R. , Hauch Kip D. , Zhang Miqin 
Published: August 2015

AbstractThis paper reports the development of a biodegradable porous scaffold made from naturally derived chitosan and alginate polymers for bone tissue engineering. The scaffold has a 3-D interconnected porous structure and was fabricated through thermally induced phase separation. The mechanical test showed that the scaffold has compressive strength of 0.46 ± 0.02 MPa — about 4 times that of the pure chitosan scaffold. The cell-material interaction study indicated that osteoblast cells seeded on the chitosan-alginate scaffold attach and proliferate well. The mineral deposition occurred after 3 days of culture and formed large chunks after 7 days. The chitosan-alginate scaffold was also found to have desirable swelling property and was structurally stable in solutions of different pH. The chitosan-alginate scaffold can be prepared from solutions of neutral pH allowing growth factors to be incorporated homogeneously into the scaffold for sustained release. This research demonstrated a technique by which a polymer-based biodegradable scaffold can be made to have high porosity up to 92% and excellent mechanical and biological properties.
Diagnostics and treatment of congenital heart diseases in newborns
Authors: Mirolyubov L M , Petrushenko D Yu , Kalinicheva J B , Sabirova D R 
Published: August 2015

Aim. Early detection and timely appropriate surgical treatment of congenital heart disease in order to reduce infant mortality.
Methods. The algorithm was designed for the prediction of critical conditions in congenital heart disease in newborns. The algorithm is simple to use, because it does not set a pediatrician-neonatologist a difficult task for the accurate diagnosis of congenital heart disease, but leads physician from the syndromic diagnosis to a certain group of diseases and, therefore, appropriate strategy of patient treatment and management. The algorithm combines both syndromes and hemodynamic conditions causing them. The conditions are divided into fetal-dependent and fetal-independent, which determines the time of surgery. The questionnaire consisting of a series of questions with multiple choice answers helps the doctor to see into the symptoms and syndromes. The questions are made in a way to emphasize the certain signs, the details of medical history and disease progression to pediatricians. It is important to notice that 13 out of 20 questions are based on the medical history and clinical picture, 7 questions are based on the test results such as electrocardiography, radiography, and do not include echocardiography.
Results. Since 2000, the questionnaire was implemented in the Republic of Tatarstan as a recommended diagnostic algorithm for examining newborns with congenital heart disease. Since 2003, the questionnaire and algorithm for prediction of the critical conditions was introduced by the order №867 of the Ministry of Health of the Republic of Tatarstan «On measures to improve health care in congenital heart disease in children». Remote consultations with maternity hospitals are strictly based on them. They carry a certain training load, and when doctors pronounce aloud all the items of the test, the examination algorithm gradually becomes automatic.
Conclusion. During 13 years of using the proposed diagnostic algorithm for congenital heart disease with physiological rationale for palliative care and timely terms of surgery, the mortality rate from congenital heart disease in the Republic of Tatarstan has significantly dropped.
Diagnóstico do uso de ferramentas de gestão por proprietários rurais de Uberlândia - MG.
Authors: Lisboa Fernando Caixeta , Medeiros Matheus Henrique , Peixoto Jéssica Laura Miranda , Gouveia Leôncio Campos , Do Nascimento Washington Ribeiro 
Published: August 2015

O produtor rural deve se adequar, na tentativa de tornar-se consciente da gestão de sua propriedade rural, pois um melhor gerenciamento resulta em maior lucratividade e em menor custo de produção. Sendo assim, o objetivo deste trabalho foi realizar um diagnóstico do uso de ferramentas de gestão por produtores rurais do município de Uberlândia – MG. Para tanto, realizou-se a aplicação de formulários estruturados a 23 produtores rurais da referida localidade, através de pesquisa de campo, obtendo-se assim, panoramas quanto ao uso destas ferramentas. Os resultados indicam a necessidade de aprimoramento e do uso das ferramentas de gestão utilizada pelos proprietários rurais entrevistados. Detectou-se, ainda, a necessidade de abertura de um curso para esclarecimento do uso dessas ferramentas.