bluuebunny/crossref_metadata_2025_split huggingface dataset:
The use of vascular closure devices and impact on major bleeding and net adverse clinical events (NACEs) in balloon aortic valvuloplasty: A sub‐analysis of the BRAVO study
Authors: O'Neill Brian , Singh Vikas , Kini Annapoorna , Mehran Roxana , Jacobs Evan , Knopf David , Alfonso Carlos E. , Martinez Claudia A. , Martinezclark Pedro , O'Neill William , Heldman Alan W. , Yu Jennifer , Baber Usman , Kovacic Jason C. , Dangas George , Sharma Samin , Sartori Samantha , Cohen Mauricio G. 
Published: February 2013

ObjectiveTo determine the impact of suture‐mediated vascular closure devices (VCDs) on net adverse clinical events (NACEs) after balloon aortic valvuloplasty (BAV).BackgroundIschemic and bleeding complications are common following transfemoral BAV; however, previous studies have been single center and limited by varying definitions of major bleeding.MethodsThe Effect of Bivalirudin on Aortic Valve Intervention Outcomes (BRAVOs) study was a retrospective observational study conducted at two high‐volume academic centers over a 6‐year period designed to compare the effect of bivalirudin versus unfractionated heparin. This is a subanalysis of 428 consecutive patients who underwent BAV (with 10–13 French sheaths) to compare the effect of hemostasis with VCDs versus manual compression utilizing standardized definitions. NACE was defined as the composite of major bleeding and major adverse clinical events (MACEs). All events were adjudicated by an independent clinical events committee who were blinded to antithrombin use.ResultsPreclosure was performed in 269 (62.8%) of patients. While bivalirudin was used more frequently in those with pre‐closure (60.6% vs. 37.7%, P < 0.001), a history of prior BAV (11.1% vs. 3.6%, P = 0.04) and peripheral vascular disease (30.7% vs. 19.7%, P = 0.01) was more common in those not undergoing preclosure (n = 159, 37%). Other clinical and demographic features were well balanced between groups. Vascular closure was associated with a significant reduction in NACE (24.5% vs. 10.0% P < 0.001). Results remained significant after adjusting for baseline differences and bivalirudin use (OR 0.38, 95% CI: 0.21–0.68; P = 0.001).ConclusionsOur study suggests that suture‐mediated vascular closure is associated with a substantial reduction in NACE after transfemoral BAV. Large randomized clinical trials should be conducted to confirm our results.© 2013 Wiley Periodicals, Inc.
Solvent and Structural Effects on the Activation Parameters of the Reaction of Carboxylic Acids with Diazodiphenylmethane
Authors: Nikolić J. B. , Ušćumlić G. S. 
Published: February 2013

ABSTRACTThe kinetics of the reaction of benzoic, 2‐methylbenzoic, phenylacetic, cyclohex‐1‐enecarboxylic, 2‐methylcyclohex‐1‐enecarboxylic, and cyclohex‐1‐eneacetic acids with diazodiphenylmethane was studied at 30, 33, 37, 40, and 45°C in a set of 12 protic and aprotic solvents. The reactions were found to follow the second‐order kinetics. The activation energy as well as the activation parameters, such as the standard entropy, the standard enthalpy, and the standard Gibbs energy of the activation, was calculated from the second‐order rate constants. The solvent and structural effects on the activation energy and the standard Gibbs energy of activation, for each examined compound, were analyzed. The results of Kamlet–Taft multiple correlation analysis show that the specific solvent–solute interactions play a dominant role in the governing of the reaction. The signs of the equation coefficients support the proposed reaction mechanism.
Dispersion relations of dust lattice waves in two-dimensional honeycomb configuration
Authors: FAROKHI B. 
Published: February 2013

AbstractThe linear dust lattice waves propagating in a two-dimensional honeycomb configuration is investigated. The interaction between particles is considered up to distance 2a, i.e. the third-neighbor interactions. Longitudinal and transverse (in-plane) dispersion relations are derived for waves in arbitrary directions. The study of dispersion relations with more neighbor interactions shows that in some cases the results change physically. Also, the dispersion relation in the different direction displays anisotropy of the group velocity in the lattice. The results are compared with dispersion relations of the waves in the hexagonal lattice.
Up or Out: Research Incentives and Career Prospects of Postdocs in Germany
Authors: Fitzenberger Bernd , Schulze Ute 
Published: February 2013

AbstractAcademic careers in Germany have been under debate for a while. We conduct a survey among postdocs in Germany to analyze the perceptions and attitudes of postdocs regarding their research incentives, their working conditions, and their career prospects. We conceptualize the career prospects of a postdoc in a life-cycle perspective of transitions from academic training to academic or non-academic jobs. Only about half of the postdocs sees strong incentives for academic research, but there is quite a strong confidence to succeed in an academic career. Furthermore, postdocs who attended a PhD program show better career prospects and higher research incentives compared to others. Academic career prospects and motivation are strongest for assistant professors. Apart from this small group, however, postdocs report only a small impact of the university reforms of the last decade. Female postdocs show significantly higher research incentives but otherwise we find little gender differences. Finally, good prospects in nonacademic jobs are not associated with a reduction in the motivation for research.
Implantable Cardioverter Defibrillators in Patients with Cardiac Amyloidosis
Authors: LIN GRACE , DISPENZIERI ANGELA , KYLE ROBERT , GROGAN MARTHA , BRADY PETER A. 
Published: February 2013

ICD in Cardiac AmyloidosisBackgroundCardiac amyloidosis (CA) is associated with increased risk of sudden cardiac arrest. Although ICD therapy improves survival in patients with cardiomyopathy due to other etiologies, the benefit of ICD therapy in patients with CA is unclear in large part due to limited data on the precise mechanism of sudden cardiac arrest and selection of patients with cardiac amyloidosis for ICD therapy.ObjectiveThe objective was to determine the benefit of ICD therapy in cardiac amyloidosis.MethodsWe reviewed all ICD implant indications, procedures, and therapies, of CA patients evaluated at Mayo Clinic between 2000 and 2009.ResultsA total of 53 patients with CA (33 AL, 10 senile, 9 familial, and 1 AA) who underwent ICD implantation were included. Indication for ICD implantation was for primary prevention of sudden cardiac arrest in 41 (77%) patients and secondary prevention in 12 (23%) patients. The rate of appropriate ICD shocks was 32% in the first year and was observed almost exclusively in AL amyloidosis patients, occurring in 15 patients (12 AL amyloidosis, 2 senile, 1 AA). Appropriate ICD shocks were more frequent in patients with prior sudden cardiac arrest or sustained ventricular arrhythmias (secondary prevention indication), and less frequent in patients who presented with decreased ejection fraction or syncope.ConclusionsA high rate of appropriate ICD shocks was observed especially in patients with AL‐type amyloidosis. However, appropriate ICD therapy did not translate into overall survival benefit, suggesting that selection of patients with CA who might be candidates for ICD is imprecise.
Prognotic impact of serum follistatin in patients with hepatocellular carcinoma
Authors: Tomoda Takeshi , Nouso Kazuhiro , Miyahara Koji , Kobayashi Sayo , Kinugasa Hideaki , Toyosawa Junki , Hagihara Hiroaki , Kuwaki Kenji , Onishi Hideki , Nakamura Shinichiro , Ikeda Fusao , Miyake Yasuhiro , Shiraha Hidenori , Takaki Akinobu , Yamamoto Kazuhide 
Published: February 2013

AbstractBackground and AimFollistatin (FST) is a glycoprotein expressed in most organs, which interacts with activins or other members of the transforming growth factor beta family. Recently, several reports have shown that FST regulates a variety of processes during tumor progression. Here, serum FST in patients with liver diseases was measured, and its clinical utility as a biomarker was assessed.MethodsSerum was collected from 162 patients (91 hepatocellular carcinoma [HCC], 43 liver cirrhosis, and 28 chronic hepatitis) as well as from 16 healthy volunteers. FST was quantified by enzyme‐linked immunosorbent assays, and levels were compared with clinical parameters including survival of the HCC patients.ResultsMedian serum FST levels in HCC, liver cirrhosis, chronic hepatitis, and healthy volunteers were 1168, 1606, 1324, and 1661 pg/mL, respectively, not significantly different. In HCC patients, higher serum FST was associated with greater age, hepatitis C virus antibody‐negativity, large tumor size, g‐glutamyl transpeptidase, des‐gamma carboxyprothrombin and presence of portal vein tumor thrombus. Survival of HCC patients with high FST levels was significantly shorter than for those with low levels (P = 0.004). Multivariate analysis revealed that in addition to large tumor size and presence of portal vein thrombus, high FST levels were independently correlated with poor prognosis (hazard ratio = 2.41, 95% confidence interval = 1.16–5.00, P = 0.02).ConclusionsSerum FST levels are significantly associated with HCC prognosis and could represent a predictive biomarker in this disease.
The recognized benefits of negative thinking/affect in depression and anxiety: Developing a scale
Authors: Sasaki Jun , Sakamoto Shinji , Moriwaki Aiko , Inoue Kai , Ugajin Kenkichi 
Published: February 2013

AbstractNegative thinking/affect (NTA) in depression and anxiety is an important target of clinical intervention. However, individuals recognize the benefit of NTA. There is a need to develop a scale for empirical studies of NTA. Two‐hundred and fifty‐nine Japanese university students were assigned to answer: (a) the state in the past week (positive affect (PA) and Center for Epidemiologic Studies Depression Scale), (b) the current state (PA and State‐Trait Anxiety Inventory‐State (STAI‐S)), and (c) the usual state (PA and STAI‐Trait), after completing the Recognized Benefit of NTA Scale (RBNTA). Another 291 students completed the Rosenberg Self‐Esteem Scale and the Revised Life Orientation Test, after completing the RBNTA. Two weeks later, 76 participants completed the RBNTA. The RBNTA with nine subscales was developed after comparing the indices of fitness from 14 different factor solutions. The internal and test‐retest reliability and content validity were confirmed. Correlation analyses revealed that the recognition of trying to obtain benefits/avoid costs tends to associate with positive/negative affect and that most of such recognitions did not associate with self‐esteem and optimism.
An Evaluation of Wikipedia as a Resource for Patient Education in Nephrology
Authors: Thomas Garry R. , Eng Lawson , de Wolff Jacob F. , Grover Samir C. 
Published: February 2013

AbstractWikipedia, a multilingual online encyclopedia, is a common starting point for patient medical searches. As its articles can be authored and edited by anyone worldwide, the credibility of the medical content of Wikipedia has been openly questioned. Wikipedia medical articles have also been criticized as too advanced for the general public. This study assesses the comprehensiveness, reliability, and readability of nephrology articles on Wikipedia. The International Statistical Classification of Diseases and Related problems, 10th Edition (ICD‐10) diagnostic codes for nephrology (N00–N29.8) were used as a topic list to investigate the English Wikipedia database. Comprehensiveness was assessed by the proportion of ICD‐10 codes that had corresponding articles. Reliability was measured by both the number of references per article and proportion of references from substantiated sources. Finally, readability was assessed using three validated indices (Flesch‐Kincaid grade level, Automated readability index, and Flesch reading ease). Nephrology articles on Wikipedia were relatively comprehensive, with 70.5% of ICD‐10 codes being represented. The articles were fairly reliable, with 7.1 ± 9.8 (mean ± SD) references per article, of which 59.7 ± 35.0% were substantiated references. Finally, all three readability indices determined that nephrology articles are written at a college level. Wikipedia is a comprehensive and fairly reliable medical resource for nephrology patients that is written at a college reading level. Accessibility of this information for the general public may be improved by hosting it at alternative Wikipedias targeted at a lower reading level, such as the Simple English Wikipedia.
Genome Sequence of Mycoplasma feriruminatoris sp. nov., a Fast-Growing
Mycoplasma
Species
Authors: Fischer Anne , Santana-Cruz Ivette , Giglio Michelle , Nadendla Suvarna , Drabek Elliott , Vilei Edy M. , Frey Joachim , Jores Joerg 
Published: February 2013

ABSTRACT

Members of the “
Mycoplasma mycoides
cluster” represent important livestock pathogens worldwide. We report the genome sequence of
Mycoplasma feriruminatoris
sp. nov., the closest relative to the “
Mycoplasma mycoides
cluster” and the fastest-growing
Mycoplasma
species described to date.
MITEs in the promoters of effector genes allow prediction of novel virulence genes in Fusarium oxysporum
Authors: Schmidt Sarah M , Houterman Petra M , Schreiver Ines , Ma Lisong , Amyotte Stefan , Chellappan Biju , Boeren Sjef , Takken Frank L W , Rep Martijn 
Published: February 2013

Abstract

Background
The plant-pathogenic fungus Fusarium oxysporum f.sp.lycopersici (Fol) has accessory, lineage-specific (LS) chromosomes that can be transferred horizontally between strains. A single LS chromosome in the Fol4287 reference strain harbors all known Fol effector genes. Transfer of this pathogenicity chromosome confers virulence to a previously non-pathogenic recipient strain. We hypothesize that expression and evolution of effector genes is influenced by their genomic context.

Results
To gain a better understanding of the genomic context of the effector genes, we manually curated the annotated genes on the pathogenicity chromosome and identified and classified transposable elements. Both retro- and DNA transposons are present with no particular overrepresented class. Retrotransposons appear evenly distributed over the chromosome, while DNA transposons tend to concentrate in large chromosomal subregions. In general, genes on the pathogenicity chromosome are dispersed within the repeat landscape. Effector genes are present within subregions enriched for DNA transposons. A miniature Impala (mimp) is always present in their promoters. Although promoter deletion studies of two effector gene loci did not reveal a direct function of the mimp for gene expression, we were able to use proximity to a mimp as a criterion to identify new effector gene candidates. Through xylem sap proteomics we confirmed that several of these candidates encode proteins secreted during plant infection.

Conclusions
Effector genes in Fol reside in characteristic subregions on a pathogenicity chromosome. Their genomic context allowed us to develop a method for the successful identification of novel effector genes. Since our approach is not based on effector gene similarity, but on unique genomic features, it can easily be extended to identify effector genes in Fo strains with different host specificities.
Parent smoker role conflict and planning to quit smoking: a cross-sectional study
Authors: Friebely Joan , Rigotti Nancy A , Chang Yuchiao , Hall Nicole , Weiley Victoria , Dempsey Janelle , Hipple Bethany , Nabi-Burza Emara , Murphy Sybil , Woo Heide , Winickoff Jonathan P 
Published: February 2013

Abstract

Background
Role conflict can motivate behavior change. No prior studies have explored the association between parent/smoker role conflict and readiness to quit. The objective of the study is to assess the association of a measure of parent/smoker role conflict with other parent and child characteristics and to test the hypothesis that parent/smoker role conflict is associated with a parent’s intention to quit smoking in the next 30 days. As part of a cluster randomized controlled trial to address parental smoking (Clinical Effort Against Secondhand Smoke Exposure—CEASE), research assistants completed exit interviews with 1980 parents whose children had been seen in 20 Pediatric Research in Office Settings (PROS) practices and asked a novel identity-conflict question about “how strongly you agree or disagree” with the statement, “My being a smoker gets in the way of my being a parent.” Response choices were dichotomized as “Strongly Agree” or “Agree” versus “Disagree” or “Strongly Disagree” for the analysis. Parents were also asked whether they were “seriously planning to quit smoking in 30 days.” Chi-square and logistic regression were performed to assess the association between role conflict and other parent/children characteristics. A similar strategy was used to determine whether role conflict was independently associated with intention to quit in the next 30 days.

Methods
As part of a RTC in 20 pediatric practices, exit interviews were held with smoking parents after their child’s exam. Parents who smoked were asked questions about smoking behavior, smoke-free home and car rules, and role conflict. Role conflict was assessed with the question, “Please tell me how strongly you agree or disagree with the statement: ‘My being a smoker gets in the way of my being a parent.’ (Answer choices were: “Strongly agree, Agree, Disagree, Strongly Disagree.”)

Results
Of 1980 eligible smokers identified, 1935 (97%) responded to the role-conflict question, and of those, 563 (29%) reported experiencing conflict. Factors that were significantly associated with parent/smoker role conflict in the multivariable model included: being non-Hispanic white, allowing home smoking, the child being seen that day for a sick visit, parents receiving any assistance for their smoking, and planning to quit in the next 30 days. In a separate multivariable logistic regression model, parent/smoker role conflict was independently associated with intention to quit in the next 30 days [AOR 2.25 (95% CI 1.80-2.18)].

Conclusion
This study demonstrated an association between parent/smoker role conflict and readiness to quit. Interventions that increase parent/smoker role conflict might act to increase readiness to quit among parents who smoke.

Trial registration
Clinical trial registration number: NCT00664261.
Press and Elections in the French Revolution of 1848: The Case of Lyon
Authors: Popkin Jeremy D. 
Published: February 2013

The French legislative election of April 23, 1848, was one of the first examples of a ritual that has become central to modern democracy: the consecration by a population of a new political order to replace a fallen regime. The newspaper press played a major but little-studied role in ensuring that the election was held relatively smoothly and that the results were generally accepted by the population. This case study, based on the press of Lyon, France’s second largest city, shows, however, the role of the press in 1848 was very different from what it had been in 1830. Despite many years of preparation, the republican opposition journalists of 1848 were resoundingly disavowed by the voters, whereas papers representing the conservative parties and the democratic-socialist movement were more successful in promoting their candidates.
Les élections d’avril 1848 sont le premier exemple d’un rituel qui est devenu central dans la démocratie moderne: la consécration par une population d’un ordre politique nouveau en remplacement d’un « ancien régime » tombé. La presse quotidienne a joué un rôle majeur mais peu étudié en assurant cette transition. Cette étude de la presse de Lyon, deuxième ville de France, montre cependant que le rôle de la presse en 1848 était très différent de ce qu’il a été en 1830. Malgré plusieurs années de préparation, les journalistes républicains de l’opposition de 1848 ont été solennellement désavoués par les électeurs, tandis que les journaux représentant les forces conservatrices et le mouvement social-démocrate ont eu plus de succès.
Laparoscopos sigmaresectio situs inversus totalisban
Authors: Berencsi Attila , Bezsilla János , Sikorszki László , Temesi Rita , Bende Sándor 
Published: February 2013

Absztrakt
A situs inversus totalis (SIT) egy ritka, veleszületett rendellenesség, amelyben a hasi és mellkasi szervek mindegyike tükörkép-pozícióban helyezkedik el. Egy 57 éves, ismert situs inversusos férfit széklethabitus-változás, véres székletürítés miatt kezdtünk vizsgálni. A colonoscopia és a hasi, kismedencei CT-vizsgálat stenotizáló sigmatumort igazolt. Osztályunkon az elektív laparoscopos vastagbél-resectio a nyitott műtét alternatívája, mintegy 60%-ban választott eljárás. Cikkünkben Magyarországon elsőként számolunk be sikeres, dokumentált, tumor miatt végzett laparoscopos sigmaresectióról situs inversus totalisban. Áttekintést adunk a biztonságos műtéti technikáról, melyet fotóval dokumentáltunk. Megfelelő anatómiai ismeret és kellő haladó laparoscopos jártasság esetén a laparoscopos resectio ilyen különleges, ritka esetben is biztonsággal alkalmazható eljárás.
Ways of Representing Accumulation: The Archive and the Collection in Jonathan Safran Foer’s Everything is Illuminated and John Fowles’ the Collector
Authors: Ada Erika 
Published: February 2013

Abstract
The paper explores the desire of accumulating in our contemporary society by analysing two processes: that of archiving and that of collecting; and how these are represented in literature, in novels such as Everything is Illuminated, which deals with the preservation of memory through the archive; and The Collector, which brings a different perspective on the act of collecting, namely, the relationship between collecting, possession and fetishism.
The Impossible Tradition of the Pindaric Ode in England
Authors: Barna Zsófia 
Published: February 2013

Abstract The “burden of the past” (W. J. Bate) has persistently remained in the focus of poets’ attention across various periods of the history of Western poetry. Questions of tradition, historical belatedness, and “anxieti[es] of influence” (H. Bloom) have fueled both theorists and practitioners of poetry. The English Pindaric tradition confronts these questions uniquely. It has shown consciousness of its own historicity from the beginning. The vocation of the Pindaric poet and his relation to the inimitable master, Pindar, persist as central themes throughout the reception history. They contribute to the evolution of a tradition where poets increasingly question the possibility of autonomous poetic creation.
Planning and Financing Schemes Linked to the Decision-Making for the Interconnection of Long-Short Distance Transport
Authors: Nathanail Eftihia , Adamos Giannis 
Published: February 2013

Abstract
The development of interfaces between long and short distance transport networks is associated with the general processes planned by central governmental bodies; and the degree of their efficiency depends heavily on the successful cooperation among the involved planning stakeholders at various territorial levels. At the same time, no matter how efficient the planning process may be the lack of the appropriate financial planning and the coordination of the involved stakeholders for finding the required resources, affects the development of successful long and short-distance interfaces.
Towards this direction, the aim of the present paper is to investigate the planning and financing schemes developed in longshort interconnection in representative European countries, and assess how these processes are linked to the decision-making processes at a local, regional, national and European level. In addition, obstacles and barriers in the relative processes are indicated and methods for their alleviation are proposed.