bluuebunny/crossref_metadata_2025_split huggingface dataset:
Truths and Misinformation: A Qualitative Exploration of Myotonic Dystrophy
Authors: LaDonna Kori A. , Ghavanini Amer A. , Venance Shannon L. 
Published: April 2015

AbstractBackground:Myotonic dystrophy (DM1) is an autosomal dominant, progressive, and multisystem condition that impacts affected individuals physically, socially, and emotionally. Understanding individuals’ perceptions of their disease is critical to ensuring appropriate information, education, and counseling.Methods:We conducted a content analysis of findings from a larger study that used a novel, qualitative research approach called photovoice to explore nine patients’ experiences of living with DM1. Participants took pictures that illustrated barriers or facilitators to living with DM1; their photographs then formed the basis of semistructured interviews. Transcripts were analyzed and, among themes, we identified one titled “DM1 truths and misinformation” that described participants’ disease knowledge. Analysis revealed four categories within this broader theme: “the physical and emotional cost of DM1,” “managing my DM1,” “genetics and me” and “patients as advocates and educators.”Results:Findings showed that DM1 participants had good core knowledge with respect to their disease and its implications. However, each participant held as fact fragments of misinformation that shaped decision-making and pointed to a clear need for strategies to mitigate variable interpretation of health information.Conclusions:We conclude that there is a need for increased education and awareness about symptoms, genetic information and treatment strategies for patients, their family members, and health care providers.
ON THE INTIMATE RELATIONSHIP OF KNOWLEDGE AND ACTION
Authors: Anderson Charity 
Published: April 2015

AbstractPragmatic encroachment offers a picture of knowledge whereby knowledge is unstable. This paper argues that pragmatic encroachment is committed to more instability than has been hitherto noted. One surprising result of the arguments in this paper is that pragmatic encroachment is not merely about changes in stakes. All sorts of practical factors can make for the presence or absence of knowledge on this picture – stakes are just one factor among many that are knowledge-depriving. In this way, the focus in the literature on ‘stakes-sensitivity’ is misleading. Furthermore, insufficient attention has been paid to the variety of ways in which on this view pragmatic factors affect knowledge: pragmatic factors are not merely knowledge-depriving but are also knowledge-inducing.
WHAT SEEMINGS SEEM TO BE
Authors: Taylor Samuel A. 
Published: April 2015

AbstractAccording to Phenomenal Conservatism (PC), if it seems to a subject S that P, S thereby has some degree of (defeasible) justification for believing P. But what is it for P to seem true? Answering this question is vital for assessing what role (if any) such states can play. Many have appeared to adopt a kind of non-reductionism that construes seemings as intentional states which cannot be reduced to more familiar mental states like beliefs or sensations. In this paper I aim to show that reductive accounts need to be taken more seriously by illustrating the plausibility of identifying seemings and conscious inclinations to form a belief. I briefly close the paper by considering the implications such an analysis might have for views such as PC.
HUMAN KNOWLEDGE/HUMAN KNOWERS: COMMENTS ON MICHAEL WILLIAMS' “WHAT'S SO SPECIAL ABOUT HUMAN KNOWLEDGE?”
Authors: Fantl Jeremy 
Published: April 2015

AbstractIn Michael Williams' “What's So Special About Human knowledge?” he argues that the kind of knowledge characteristic of adult humans is distinctive in that it involves epistemic responsibility. In particular, when an adult human has knowledge, they have a certain kind of epistemic authority, and that to attribute knowledge to them is to grant them a certain kind of authority over the subject matter. I argue that, while it is true that when we attribute knowledge to adult humans, we typically also attribute to them the relevant kind of epistemic authority, this need not be because adult humans have a distinctive kind of knowledge. Rather, it may be because adult humans are distinctive kinds of beings - beings that can have epistemic authority over the subject matter about which they know. The only thing that need be special about human knowledge is that it's had by human knowers.
Differences between men and women in dietary intakes and metabolic profile in response to a 12-week nutritional intervention promoting the Mediterranean diet
Authors: Leblanc Vicky , Hudon Anne-Marie , Royer Marie-Michelle , Corneau Louise , Dodin Sylvie , Bégin Catherine , Lemieux Simone 
Published: April 2015

AbstractFew studies have compared men and women in response to nutritional interventions but none has assessed differences between men and women in the response to a nutritional intervention programme based on the self-determination theory (SDT) and using the Mediterranean diet (MedDiet) as a model of healthy eating, in a context of CVD prevention and within a non-Mediterranean population. The present study aimed to document differences between men and women in changes in dietary, anthropometric and metabolic variables, in response to a nutritional intervention programme promoting the adoption of the MedDiet and based on the SDT. A total of sixty-four men and fifty-nine premenopausal women presenting risk factors for CVD were recruited through different media advertisements in the Québec City Metropolitan area (Canada). The 12-week nutritional programme used a motivational interviewing approach and included individual and group sessions. A validated FFQ was administered to evaluate dietary intakes from which a Mediterranean score (Medscore) was derived. Both men and women significantly increased their Medscore in response to the intervention (P < 0·0001). Men showed a significantly greater decrease in red and processed meat (−0·4 (95 % CI −0·7, −0·1) portions per d) and a greater increase in fruit (0·9 (95 % CI 0·2, 1·6) portions per d) intakes than women. Significant decreases were observed for BMI and waist circumference in both men and women (P ≤ 0·04). Significant greater decreases were found for total cholesterol (total-C):HDL-cholesterol (HDL-C) (−0·2; 95 % CI −0·4, −0·03) and TAG:HDL-C (−0·2; 95 % CI −0·4, −0·04) ratios in men than in women. When adjusting for the baseline value of the response variable, differences between men and women became non-significant for red and processed meat and fruit intakes whereas significant differences between men and women (i.e. larger increases in men than women) were observed for legumes, nuts and seeds (0·6 (95 % CI 0·2, 1·0) portions per d) and whole-grain products (0·5 (95 % CI 0·01, 1·0) portions per d) intakes. For metabolic variables, differences between men and women became non-significant for total-C:HDL-C and TAG:HDL-C ratios when adjusted for the baseline value of the response variable. The present results suggest that the nutritional intervention promoting the adoption of the Mediterranean diet and based on the SDT led to greater improvements in dietary intakes in men than in women, which appear to have contributed to beneficial anthropometric and metabolic changes, more particularly in men. However, the more deteriorated metabolic profile found in men at baseline seems to contribute to a large extent to the more beneficial changes in CVD risk factors observed in men as compared with women.
Hiring of Personal Ties: A Cultural Consensus Analysis of China and the United States
Authors: Liu Xiao-xiao , Keller Joshua , Hong Ying-yi 
Published: April 2015

ABSTRACTAlthough employees react negatively when employers hire individuals with whom the employers have personal ties, the practice is prevalent worldwide. One factor contributing to the discrepancy between reactions to the practice may be differences in cultural beliefs and institutions regarding perceptions about hiring decisions. To examine cross-national differences in perceptions about hiring personal ties, we conducted a consensus analysis on the perceived fairness, profitability, and overall evaluation of hiring decisions in China and the United States. We find cross-national differences in consensus levels as to whether people believe it is fair or unfair to hire moderately qualified candidates with employer ties (kinships or close friends with the employer) and whether people positively or negatively evaluate the hiring of unqualified candidates with stakeholder ties (ties to business associates or government officials). We also find contrasting areas of consensus about whether hiring unqualified candidates with stakeholder ties is profitable. Implications for research on cultural comparisons of perceptions of hiring practices andguanxiare discussed.
Distribution of vitamin C is tissue specific with early saturation of the brain and adrenal glands following differential oral dose regimens in guinea pigs
Authors: Hasselholt Stine , Tveden-Nyborg Pernille , Lykkesfeldt Jens 
Published: April 2015

Vitamin C (VitC) deficiency is surprisingly common in humans even in developed parts of the world. The micronutrient has several established functions in the brain; however, the consequences of its deficiency are not well characterised. To elucidate the effects of VitC deficiency on the brain, increased knowledge about the distribution of VitC to the brain and within different brain regions after varying dietary concentrations is needed. In the present study, guinea pigs (like humans lacking the ability to synthesise VitC) were randomly divided into six groups (n10) that received different concentrations of VitC ranging from 100 to 1500 mg/kg feed for 8 weeks, after which VitC concentrations in biological fluids and tissues were measured using HPLC. The distribution of VitC was found to be dynamic and dependent on dietary availability. Brain saturation was region specific, occurred at low dietary doses, and the dose–concentration relationship could be approximated with a three-parameter Hill equation. The correlation between plasma and brain concentrations of VitC was moderate compared with other organs, and during non-scorbutic VitC deficiency, the brain was able to maintain concentrations from about one-quarter to half of sufficient levels depending on the region, whereas concentrations in other tissues decreased to one-sixth or less. The adrenal glands have similar characteristics to the brain. The observed distribution kinetics with a low dietary dose needed for saturation and exceptional retention ability suggest that the brain and adrenal glands are high priority tissues with regard to the distribution of VitC.
Major food sources contributing to energy intake – a nationwide survey of Brazilians aged 10 years and older
Authors: Sichieri Rosely , Bezerra Ilana Nogueira , Araújo Marina Campos , de Moura Souza Amanda , Yokoo Edna Massae , Pereira Rosangela Alves 
Published: April 2015

Identification of major sources of energy in the diet helps to implement dietary recommendations to reduce obesity. To determine the food sources of energy consumed by Brazilians, we used the traditional method of ranking energy contribution of selected food groups and also compared days with and without consumption of specific food groups. Analysis was based on two non-consecutive days of dietary record from the Brazilian National Dietary Survey, conducted among 34 003 Brazilians (aged 10 years or more), taking into account the complex design of the survey. Comparison of days with and without consumption gave more consistent results, with sweets and cookies as the most important contributors to energy intake, increasing 992 kJ/d (95 % CI 883, 1096) for those days when consumption of cakes, cookies and desserts was reported compared to days without their consumption. Savoury snacks, cheese and sugar-sweetened beverages (SSB) also increase energy intake by about 600 kJ. The only group associated with decreased energy intake was vegetable ( − 155 kJ; 95 % CI − 272, − 37). Consumption of beans, milk and fruits increased the energy intake by about 210 kJ. In total, the mean energy intake of the group was 8000 kJ. Except for the consumption of vegetables, all of the other ten food groups analysed were associated with increased energy intake. Sweets and cookies may increase the energy intake by 12 % and SSB by 7 %, indicating that these two groups are major targets for improving healthy eating by reducing energy intake; whereas vegetable intake is associated with the reduction of energy content of the diet.
Education, Propaganda, and the People: Democratic paternalism in 1930s Siam
Authors: SUBRAHMANYAN ARJUN 
Published: April 2015

AbstractOn the morning of 24 June 1932 the ‘People's Party’, a small group of civil and military bureaucrats, toppled the Thai absolute monarchy and introduced constitutional democracy. This article discusses the establishment of democracy as an endeavour in ‘democratic paternalism,’ by which is meant the Party's attempt to establish a new moral and intellectual leadership that had as its main goal the creation of a depoliticized democratic citizenry. To implement their programme for democracy, the Party embarked on an ambitious plan to modernize education and explain popular sovereignty through countrywide lectures and radio programmes. The democratic paternalist effort had mixed results. State weakness limited the reach of the educational and propaganda campaigns, and further the ‘people’ in whose name the revolution was staged, constituted two different groups: a largely illiterate peasantry and a small, incipient new intelligentsia. Because of its limited capacity, the People's Party tasked the second group with assisting in democratic mentorship of the masses, but many in this second category of people had a broader conception of democracy than the Party's ‘top-down’ model and criticized the Party for its paternalist constraints on popular sovereignty. Democratic paternalism and frustration with the limits imposed on popular democracy are two central aspects of this period of history that have endured in Thai society.
How Germans prepare for the English past tense: Silent production of inflected words during EEG
Authors: FESTMAN JULIA , CLAHSEN HARALD 
Published: April 2015

ABSTRACTProcesses involved in late bilinguals’ production of morphologically complex words were studied using an event-related brain potentials (ERP) paradigm in which EEGs were recorded during participants’ silent productions of English past- and present-tense forms. Twenty-three advanced second language speakers of English (first language [L1] German) were compared to a control group of 19 L1 English speakers from an earlier study. We found a frontocentral negativity for regular relative to irregular past-tense forms (e.g., asked vs. held) during (silent) production, and no difference for the present-tense condition (e.g., asks vs. holds), replicating the ERP effect obtained for the L1 group. This ERP effect suggests that combinatorial processing is involved in producing regular past-tense forms, in both late bilinguals and L1 speakers. We also suggest that this paradigm is a useful tool for future studies of online language production.
Perspectives on ageing, later life and ethnicity: ageing research in ethnic minority contexts
Authors: ZUBAIR MARIA , NORRIS MERIEL 
Published: April 2015

ABSTRACTThis special issue focuses broadly upon questions and themes relating to the current conceptualisations, representations and use of ‘ethnicity’ (and ethnic minority experiences) within the field of social gerontology. An important aim of this special issue is to explore and address the issue of ‘otherness’ within the predominant existing frameworks for researching those who are ageing or considered aged, compounded by the particular constructions of their ethnicity and ethnic ‘difference’. The range of theoretical, methodological and empirical papers included in this collection provide some critical insights into particular facets of the current research agendas, cultural understandings and empirical focus of ethnic minority ageing research. The main emphasis is on highlighting the ways in which ethnic cultural homogeneity and ‘otherness’ is often assumed in research involving older people from ethnic minority backgrounds, and how wider societal inequalities are concomitantly (re)produced, within (and through) research itself – for example, based on narrowly defined research agendas and questions; the assumed age and/or ethnic differences of researchersvis-à-vistheir older research participants; the workings of the formalised ethical procedures and frameworks; and the conceptual and theoretical frameworks employed in the formulation of research questions and interpretation of data. We examine and challenge here the simplistic categorisations and distinctions often made in gerontological research based around research participants' ethnicity, age and ageing and assumed cultural differences. The papers presented in this collection reveal instead the actual complexity and fluidity of these concepts as well as the cultural dynamism and diversity of experiences within ethnic groups. Through an exploration of these issues, we address some of the gaps in existing knowledge and understandings as well as contribute to the newly emerging discussions surrounding the use of particular notions of ethnicity and ethnic minority ageing as these are being employed within the field of ageing studies.
Investigation of a measles outbreak in Zimbabwe, 2010: potential of a point of care test to replace laboratory confirmation of suspected cases
Authors: SHONHAI A. , WARRENER L. , MANGWANYA D. , SLIBINSKAS R. , BROWN K. , BROWN D. , FEATHERSTONE D. , SAMUEL D. 
Published: April 2015

SUMMARYBlood and oral fluid (OF) samples were collected from 103 suspected measles cases between February and November 2010 during a nationwide measles outbreak in Zimbabwe. Siemens measles IgM enzyme immunoassay (EIA) on serum, Microimmune measles IgM capture EIA on OF, real-time haemagglutinin (H) gene PCR and nested nucleocapsid (N) gene PCR on OF were performed, confirming 75 measles cases. These samples were then used to evaluate a newly developed point of care test (POCT) for measles and determine its potential for identifying measles cases in outbreaks. After performing POCTs on OF samples, nucleic acid was extracted from the used test strips and the measles H and N genes amplified by RT–PCR. The sensitivity, specificity, positive and negative predictive values of the POCT for IgM in OF was 75·0% [95% confidence interval (CI) 63·4–84·5], 96·2% (95% CI 80·4–99·9), 98·2% (95% CI 90·3–100) and 58·1% (95% CI 42·1–73·0), respectively. The N gene sequences showed high level of agreement between original OF and corresponding POCT strips. Measles genotype B3 was identified in all cases. We conclude that the measles POCT has the potential to be used, at the point of contact, in outbreak situations and provide molecular characterization of the virus at a later date.
Determination of cut-off cycle threshold values in routine RT–PCR assays to assist differential diagnosis of norovirus in children hospitalized for acute gastroenteritis
Authors: TRANG N. V. , CHOISY M. , NAKAGOMI T. , CHINH N. T. M. , DOAN Y. H. , YAMASHIRO T. , BRYANT J. E. , NAKAGOMI O. , ANH D. D. 
Published: April 2015

SUMMARYNorovirus (NV) is an important cause of acute gastroenteritis in children, but is also frequently detected in asymptomatic children, which complicates the interpretation of NV detection results in both the clinical setting and population prevalence studies. A total of 807 faecal samples from children aged <5 years hospitalized for acute gastroenteritis were collected in Thai Binh, Vietnam, from January 2011 to September 2012. Real-time RT–PCR was used to detect and quantify NV-RNA in clinical samples. A bimodal distribution of cycle threshold (Ct) values was observed in which the lower peak was assumed to represent cases for which NV was the causal agent of diarrhoea, whereas the higher peak was assumed to represent cases involving an alternative pathogen other than NV. Under these assumptions, we applied finite-mixture modelling to estimate a threshold of Ct<21·36 (95% confidence interval 20·29–22·46) to distinguish NV-positive patients for which NV was the likely cause of diarrhoea. We evaluated the validity of the threshold through comparisons with NV antigen ELISA results, and comparisons of Ctvalues in patients co-infected with rotavirus. We conclude that the use of an appropriate cut-off value in the interpretation of NV real-time RT–PCR results may improve differential diagnosis of enteric infections, and could contribute to improved estimates of the burden of NV disease.
Risk prediction tools for older general surgical patients
Authors: Middleton M , Stechman MJ , Moug S , McCarthy K , Hewitt J 
Published: April 2015

SummaryThis review identifies and examines the clinical application of risk prediction tools, including the American Society of Anaesthesiology (ASA) Classification System and POSSUM-based scores, in the older general surgical patient. Predicting outcomes in this patient group remains difficult; it is challenging to design a risk prediction tool that will apply to both emergency and elective surgery and that remains valid across the wide age range that this patient group encompasses. Risk prediction tools can have benefit but should be used in conjunction with the clinical assessment of those experienced in the care of this challenging patient group.
The Cold War and Socialist Identity: The Socialist International and the Italian ‘Communist Question’ in the 1970s
Authors: DI DONATO MICHELE 
Published: April 2015

AbstractComing about in a phase of renewal and electoral success for the European socialist parties, the rise of the Italian Communist Party in the 1970s elicited differentiated reactions within the Socialist International. While providing an account of the transnational socialist debate on Italian Eurocommunism, this article suggests to understand it in the context of a wider discussion on the political identity and aims of the European left. Divisions on the new ‘communist question’ amongst the socialist movement mirrored the divergent opinions on how to react to the changes that were taking place in European economics and society, as well as in the international system.
Religious Regimes: Rethinking the Societal Role of Religion in Post-War Europe
Authors: VAN DAM PETER , VAN TRIGT PAUL 
Published: April 2015

AbstractThis article discusses the concept of ‘religious regimes’ in order to identify institutionalised arrangements regulating the social position of religion. By analysing such regimes and the views underpinning them, three visions of the societal role of religion come into focus: segmented pluralism, the Christian nation and the secular nation. Taking up Dutch post-war history as a case study, it becomes clear that religious regimes regularly result from fragile compromises. The concept thus yields insight into the gradual transitions between different institutional arrangements regarding religion and into the impact of changing views on the societal role of religion within and outside religious communities.
The European Community's Public Communication Policy 1951–1967
Authors: HARRISON JACKIE , PUKALLUS STEFANIE 
Published: April 2015

AbstractFrom its inception the European Community had a civil aim: the need to stimulate a European civil consciousness. Viewed as a pre-condition for the popular acceptance of increased European integration, this provided the rationale for the Community's public communication policy of 1951–1967. The Community pursued this civil aim through two distinct public communication approaches: popularist (1951–1962) and opinion leader led (1963–1967). We contend that the way the Community undertook its public communication policy cannot be understood without considering the Community's civil aim. This leads us to question some of the common views held concerning the significance of European public communication policy from 1951 to 1967.1