bluuebunny/crossref_metadata_2025_split huggingface dataset:
Text messages to improve young child diets: Results from a cluster‐randomized controlled trial in Kanchanpur, Nepal
Authors: Cunningham Kenda , Cech Sidney , Gupta Aman Sen , Rana Pooja Pandey , Humphries Debbie , Frongillo Edward A. 
Published: July 2024

AbstractThe objective of this study was to test whether adding a text message campaign about the importance of eating eggs and other nutrition‐related behaviours to an on‐going package of large‐scale, diverse social and behaviour change interventions would improve four types of nutrition‐related knowledge and behaviour outcomes: child diets (egg consumption as the primary outcome), maternal diets, maternal nutrition knowledge, and maternal participation in additional interventions. The cluster‐randomized controlled trial involved a repeat cross‐sectional design, recruiting families with children 12–23 months of age at baseline and endline in one plains district of Nepal. Throughout the 1000‐day period, 51 text messages were sent to each household at specific time points to reinforce ideal diets and other nutrition‐related practices and promote engagement with community health workers and other intervention platforms. The primary outcome was egg consumption and dietary diversity among young children. We found no population‐level effect. Some evidence supports that for those who received and opened the SMS intervention, it improved child egg consumption (odds ratio [OR]: 1.41, 95% confidence interval [CI]: 1.03–1.93), child minimum dietary diversity (OR: 1.36, 95% CI: 1.07–1.73), child dietary diversity scores (β: 0.15, 95% CI: 0.01–0.24), as well as maternal IYCF knowledge (β: 0.21, 95% CI: 0.08–0.35), participation in health mothers' group meetings (OR: 3.03, 95% CI: 1.91–4.84) and Bhanchhin Aama listenership (OR: 1.36, 95% CI: 1.07–1.73). This study highlights the importance of more research to understand the effectiveness of emerging digital interventions for behaviour change among specific populations, to facilitate nuanced targeting to those who can best benefit from these investments. Registered at clinicaltrials.gov with identifier NCT03926689.
(Re)constructing and (re)negotiating identities: A case study of postsecondary language teachers and social justice education
Authors: Paesani Kate , Goodspeed Lauren , Menke Mandy , Ruf Helena 
Published: July 2024

AbstractThis study explores the identity formation of two postsecondary language teachers and course coordinators—one in German and one in French—as they created intermediate‐level, content‐based social justice curricular units for a multiyear project. Using a multiple‐case‐study methodology and cultural–historical activity theory, this qualitative investigation answers the following research question: How do experienced postsecondary language teachers (re)construct and (re)negotiate their identities while developing social justice teaching materials? Findings, based on multicycle descriptive coding, reveal that participants’ past experiences, personal values, feelings of self‐doubt, and positionality as content‐based language teachers influenced their language teacher identity, as did tensions within and across three activity systems: the curriculum development project, classroom teaching, and the coordination of multisection courses. These findings have important implications for teacher professional development and community building related to social justice in language education.
The morphology of alveolar bone of the mandibular second and third molars in skeletal Class III patients
Authors: Jiang Liya , Weng Luxi , Yu Xin , Lin Jun 
Published: July 2024

AbstractObjectivesTo investigate the alveolar bone morphology of the mandibular second and third molars in skeletal Class III patients from a buccolingual direction.MethodsSixty skeletal Class III patients were recruited. The alveolar bone width, buccal cortical bone thickness and lingual cortical bone thickness were measured in five planes from mesial to distal and at five depths from gingival to root. The effects of the gender of the patients, the second molar lingual inclination and the third molar on alveolar bone width and cortical bone thickness were evaluated. To explore the effect of third molar extraction on alveolar bone morphology, the measurements before and after third molar extraction were compared.ResultsThe impacted third molar had significantly greater alveolar bone width and thicker buccal cortical bone at the cervical third of the molar, while the erupted third molar had greater alveolar bone width at the apical third. Three weeks after third molar extraction, these advantages would weaken owing to the reconstruction of the alveolar bone. Patients with lingually inclined molar were observed to own thicker lingual cortical bone. Males tended to have greater alveolar bone width, but no significant differences were shown in this study.ConclusionsThe growth of the third molar and the second molar lingual inclination affect the alveolar bone morphology of the mandibular second and third molars significantly, but gender has trivial effects on the morphology. The alveolar bone morphology of the mandibular second and third molars would change 3 weeks after third molar extraction.
Sextuple knockouts of a highly conserved and coexpressed AUXIN/INDOLE‐3‐ACETIC ACID gene set confer shade avoidance‐like responses in Arabidopsis
Authors: Yang Xinxing , Ma Yuan , Chen Jie , Huang Minhua , Qi Mengyuan , Han Ning , Bian Hongwu , Qiu Ting , Yan Qingfeng , Wang Junhui 
Published: July 2024

AbstractAUXIN/INDOLE‐3‐ACETIC ACIDs are transcriptional repressors for auxin signalling. Aux/IAAs of Arabidopsis thaliana display some functional redundancy. The IAA3/SHY2 clade (IAA1, IAA2, IAA3 and IAA4) show strong sequence similarity, but no higher‐order mutants have been reported. Here, through CRISPR/Cas9 genome editing, we generated loss‐of‐function iaa1/2/3/4 mutants. The quadruple mutants only exhibited a weak phenotype. Thus, we additionally knocked out IAA7/AXR2 and IAA16, which are coexpressed with IAA1/2/3/4. Remarkably, under white light control conditions, the iaa1/2/3/4/7/16 mutants exhibited a shade avoidance‐like phenotype with over‐elongated hypocotyls and petioles and hyponastic leaves. The sextuple mutants were highly sensitive to low light intensity, and the hypocotyl cells of the mutants were excessively elongated. Transcriptome profiling and qRT‐PCR analyses revealed that the sextuple mutation upregulated IAA19/MSG2 and IAA29, two shared shade/auxin signalling targets. Besides, genes encoding cell wall‐remodelling proteins and shade‐responsive transcription regulators were upregulated. Using dual‐luciferase reporter assays, we verified that IAA2/IAA7 targeted the promoters of cell wall‐remodelling genes to inhibit their transcription. Our work indicates that the IAA1/2/3/4/7/16 gene set is required for the optimal integration of auxin and shade signalling. The mutants generated here should be valuable for exploring the complex interactions among signal sensors, transcription activators and transcription repressors during hormone/environmental responses.
Pediatric cutaneous Crohn disease: A case series of 89 patients and review
Authors: McKay Grace E. , Liu Lynn , Shaw Katharina S. , Shakshouk Hadir , Murphy Michael J. , Damsky William , Ortega‐Loayza Alex G. , Caplan Avrom S. , Arkin Lisa M. , Shields Bridget E. 
Published: July 2024

AbstractBackgroundCutaneous (or “Metastatic”) Crohn disease (CCD) is a rare and underrecognized disease characterized by cutaneous granulomatous inflammation. We describe patient demographics, clinical characteristics, histology, and treatment of 89 pediatric cases of CCD, including 78 previously reported and 11 new cases seen at four academic institutions. We emphasize the efficacy of biologic mono‐ and dual therapy.MethodsPubMed identified cases using keywords including “metastatic Crohn disease” and “cutaneous Crohn disease”. Patients were identified by retrospective review of the electronic health record including histopathologic diagnosis consistent with CCD. Chart review collected demographic, clinical, and histologic data.ResultsMost pediatric patients with CCD are male 55% (49/89), present with edema (73/89, 82%) and erythema (47/89, 53%) of the genitals (33/49, 67%), and have intestinal Crohn disease (69/89, 78%). Oral corticosteroids (53/75, 71%) and metronidazole (29/75, 39%) are the most frequently prescribed medications. Of the 17 patients treated with tumor necrosis factor (TNF)‐blockade, 94% (16/17) had partial or total clearance. Ustekinumab resulted in clearance of cutaneous disease in two patients (2/3, 67%) and partial clearance in one patient (1/3, 33%). Two cases achieved total clearance with the use of dual biologic therapy defined as the use of two biologic therapies with differing mechanisms of action or the use of a biologic therapy and small molecule inhibitor.ConclusionsTNF blockade is an effective treatment for pediatric CCD, and interleukin‐12/23 inhibitors may be similarly effective. Consideration of dual biologic therapy may be useful in pediatric patients requiring discordant therapies for their intestinal and cutaneous CD.
Bringing the deep self back to the racecourse: Rethinking accountability and the deep self
Authors: Zhang Ke 
Published: July 2024

AbstractDeep self views of moral responsibility suggest that an agent fully satisfies the freedom condition for responsibility if and only if her actions or omissions issue from, and so express, her deep self. This analysis generates both false negatives and false positives regarding people's responsibility, and counterexamples proliferate. I defend a novel version of the deep self view by offering a necessary condition for accountability while retaining the core of deep self views. Indeed, an agent may be blameworthy for her wrongdoing without it issuing from, and so expressing, her deep self. And yet, I argue that she must have a deep self for which she is responsible. This is achieved by paying closer attention to history than standard views have. Focusing on history then reveals a less discussed problem for standard views: the ahistorical features of them make them less equipped to explain cases of blameworthiness that is undermined.
Sustainable aquaculture over the last 30 years: An analysis of the scientific literature by the Text Mining approach
Authors: Tucciarone Isabella , Secci Giulia , Contiero Barbara , Parisi Giuliana 
Published: July 2024

AbstractA literature search approach (using Scopus®, Elsevier© database) was established to identify peer‐reviewed articles published in English between 1960 and 2023 dealing with ‘sustainable aquaculture’ and focusing on specific aquaculture practices (aquaponics, integrated multi‐trophic aquaculture, biofloc and recirculating aquaculture systems). Text Mining combined with Topic Analysis was utilized to extract information from the text data of the papers identified. After an appropriate screening procedure, 1111 articles were selected. The analysis showed a gradual increase in sustainable aquaculture publications over time, peaking at more than 200 publications in 2023. The first articles on biofloc, integrated multi‐trophic aquaculture and recirculating aquaculture systems as alternative aquaculture practices began to appear in 2010, while studies in aquaponics have only been published since 2015. Most publications (40%) came from Asia, in line with the leadership of this continent in aquaculture. European also showed considerable interest in sustainable aquaculture practices, with Italy (leader in publications), Portugal and Germany researchers contributing with 111 papers on the subject in the past 30 years. This study identified the main research topics on the subject and observed how these have evolved. The papers analysed dealt mainly with optimization of aquatic life, genetic in aquaculture and disease management. The topic of protein replacement in feed was also important, with the term ‘diet’ the most frequently utilized in papers. The subjects identified could serve as valuable primary data source, offering opportunities for deeper examination, such as systematic reviews on research topics or geographic regions.
The impact of a disaster recovery policy on health status of the 2015 Gorkha earthquake victims: Evidence from a natural experiment
Authors: Huang Qiong , Bhandari Gautam , Khan Ghulam Dastgir , Yoshida Yuichiro 
Published: July 2024

AbstractThe 2015 Gorkha earthquake destroyed key infrastructure in Greater Kathmandu and the surrounding earthquake‐affected areas, undermining the health status of affected households. As one of the disaster recovery policies, the Nepalese government distributed taxi permits to severely affected households through a lottery. Leveraging on this natural experimental setting, we examine the impact of the policy on their health status and access to health services. The results show that the treated households have fewer chronic and diarrhoeal diseases, and fewer doctor visits. However, we find no significant difference in the households' medical expenditure between the two groups. We also find that rural households with the taxi permits benefit more from the policy. The results of this study may provide policymakers with some insight to enhance their post‐disaster recovery strategy.
Comparative responses of renewable energy stock market to economic policy uncertainty and climate policy uncertainty shocks: Evidence from China
Authors: Yang Xiuqi , Nie Jing 
Published: July 2024

AbstractWith rising climate policy uncertainty (CPU) and economic policy uncertainty (EPU), it is crucial to analyze the factors influencing the renewable energy stock market (RE) from a comprehensive perspective. Using data from January 2009 to May 2022, we use a time‐varying parameter vector autoregressive model with stochastic volatility (TVP‐VAR‐SV) to examine CPU, EPU, macroeconomic factors, and RE in a unified framework. We analyze the various responses of RE to CPU and EPU. Furthermore, we test for differences in the impact of the four classifications of EPU on RE. The findings are as follows. The time‐varying impact of CPU on RE is centered on the short term and is positive during non‐crisis periods. In contrast, the impact of EPU on RE is negative in the short term. In addition, causal identification at the micro level reveals that RE can increase by 0.932% on average after being affected by CPU. Further comparing the four classifications of EPU, we find that exchange rate policy uncertainty has the largest negative impact. Our study enriches the investment theory on RE. It avoids biased interpretations of various policy uncertainties and has a significant implication for policymakers, renewable energy firms, and investors.
Outcomes in solid organ transplant recipients receiving organs from a donor with Fusarium solani species complex meningitis
Authors: Griffin Isabel S. , Smith Dallas J. , Annambhotla Pallavi , Gold Jeremy A. W. , Ostrosky‐Zeichner Luis , Kauffman Carol A. , Gade Lalitha , Litvintseva Anastasia , Friedman Daniel ZP , Nishio Lucar Angie G , Parpia Tarina C , Lieberman Joshua , Bujan Janet , Corkrean Julie , Divatia Mukul K. , Grimes Kevin , Lin Jiejian , Mobley Constance , Schwartz Mary R. , Hannawi Bashar , Malilay Anne , O'Boye Anne , Lysne Jeffrey , Subramani Mrinalini Venkata , Heckmann Hayley , Servellita Venice , Chiu Charles , Basavaraju Sridhar V. 
Published: July 2024

AbstractBackgroundFive organs (heart, right lung, liver, right, and left kidneys) from a deceased patient were transplanted into five recipients in four US states; the deceased patient was identified as part of a healthcare‐associated fungal meningitis outbreak among patients who underwent epidural anesthesia in Matamoros, Mexico.MethodsAfter transplant surgeries occurred, Fusarium solani species complex, a fungal pathogen with a high case‐mortality rate, was identified in cerebrospinal fluid from the organ donor by metagenomic next‐generation sequencing (mNGS) and fungal‐specific polymerase chain reaction and in plasma by mNGS.ResultsFour of five transplant recipients received recommended voriconazole prophylaxis; four were monitored weekly by serum (1‐3)‐β‐d‐glucan testing. All five were monitored for signs of infection for at least 3 months following transplantation. The liver recipient had graft failure, which was attributed to an etiology unrelated to fungal infection. No fungal DNA was identified in sections of the explanted liver, suggesting that F. solani species complex did not contribute to graft failure. The remaining recipients experienced no signs or symptoms suggestive of fusariosis.ConclusionAntifungal prophylaxis may be useful in preventing donor‐derived infections in recipients of organs from donors that are found to have Fusarium meningitis.
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Emerging shadows: HHV‐8‐associated encephalitis unveiled in a solid organ transplant recipient
Authors: Mann Inderjit , Morado‐Aramburo Oscar , Hasbun Rodrigo 
Published: July 2024

AbstractHuman herpesviruses (HHVs) cause a wide variety of central nervous system (CNS) infections including meningitis and encephalitis. While HHV‐8 is not typically associated with neurological diseases, several studies have indicated a relationship, such as secondary central nervous system (CNS) metastases and a few isolated cases of HHV‐8 encephalitis in acquired immunodeficiency syndrome (HIV). However, it has not been previously linked to encephalitis in solid organ transplantation (SOT). This case presents the first‐ever instance of HHV‐8 encephalitis in a SOT recipient. Our case highlights the association of HHV‐8‐related diseases, such as post‐transplant Kaposi's Sarcoma (KS), with encephalitis. The patient was diagnosed with KS before developing neurological symptoms and received a prompt clinical response through intravenous foscarnet and ganciclovir treatment for 14 days. It is important to note that HHV‐8 is a rare cause of encephalitis, and diagnosis requires a high index of suspicion in the appropriate clinical context, allowing for the use of antiviral therapy. This case also underscores the importance of considering the possibility of HHV‐8‐related diseases in SOT recipients, as they are at risk of developing such infections.
Context‐dependent antisense transcription from a neighboring gene interferes with the expression of mNeonGreen as a functional in vivo fluorescent reporter in the chloroplast of Chlamydomonas reinhardtii
Authors: Navarrete Axel , Pollak Bernardo 
Published: July 2024

SUMMARYAdvancing chloroplast genetic engineering in Chlamydomonas reinhardtii remains challenging, decades after its first successful transformation. This study introduces the development of a chloroplast‐optimized mNeonGreen fluorescent reporter, enabling in vivo observation through a sixfold increase in fluorescence via context‐aware construct engineering. Our research highlights the influence of transcriptional readthrough and antisense mRNA pairing on post‐transcriptional regulation, pointing to novel strategies for optimizing heterologous gene expression. We further demonstrate the applicability of these insights using an accessible experimentation system using glass‐bead transformation and reestablishment of photosynthesis using psbH mutants, focusing on the mitigation of transcriptional readthrough effects. By characterizing heterologous expression using regulatory elements such as PrrnS, 5′atpA, and 3′ rbcL in a sense‐transcriptional context, we further documented up to twofold improvement in fluorescence levels. Our findings contribute new tools for molecular biology research in the chloroplast and evidence fundamental gene regulation processes that could enable the development of more effective chloroplast engineering strategies. This work not only paves the way for more efficient genetic engineering of chloroplasts but also deepens our understanding of the regulatory mechanisms at play.
General extenders in New Zealand Englishes
Authors: Onysko Alexander , Degani Marta 
Published: July 2024

AbstractThis paper provides insight into the use of general extenders (e.g., and stuff, or something and and whatnot) in New Zealand Englishes as spoken by Māori and New Zealand European (Pākehā) New Zealanders. Based on audio‐recorded data of prompted co‐constructed narrations, the article explores the types of general extenders and their rate of occurrence in both groups. Contrary to expectations, the group of Pākehā New Zealanders shows a significantly higher rate of using general extenders compared to the Māori participants while the preferred types of general extenders overlap to a large extent among the two speaker groups. A close‐up on the by far most widely spread general extender in both groups (and stuff) unveils interesting patterns of variation across the Māori and Pākehā New Zealanders.
A Study on the Fracture Toughness Evaluation Considering Material Tensile Characteristic for Cryogenic Steel
Authors: Kim Ji Hoon , Jeong Young Cheon , Cho Dong Pil , Kim Myung Hyun 
Published: July 2024

Abstract
ISO 12135, a representative standard for the evaluation of fracture toughness, was revised in 2021. In the previous standard published in 2016, only yield strength was reflected for material property in fracture toughness calculation. In the revised standard, however, yield to tensile strength ratio is additionally reflected in consideration of strain hardening effect of the material. The current fracture toughness calculation formula evaluates fracture toughness reasonably considering the tensile characteristic. However, in some cases of cryogenic steels, fracture toughness is evaluated very conservatively than the previous procedure in 2016. In the case of STS 304L, there is no ductile-brittle transition phenomenon and it has excellent ductility and strength in cryogenic temperature. However, due to the secondary hardening phenomenon, yield to tensile strength ratio is relatively low, and as a result, fracture toughness is evaluated very low. The target of this study is to resolve the undervaluation of fracture toughness of cryogenic steel in the revised ISO 12135. For this purpose, the elastic and the plastic parameters in crack tip opening displacement (CTOD) equation in ISO 12135 are examined. The crack tip profile is derived by a series of finite element analysis and crack tip opening displacement is calculated for the derivation of new parametric equations for cryogenic materials. The calculated crack tip opening displacement is validated by experimental results.
Review and Gap Analysis of Heliostat Components and Controls
Authors: Armijo Kenneth M. , Muller Matthew , Tsvankin Daniel , Madden Dimitri 
Published: July 2024

Abstract
This investigation provides a comprehensive literature review pertaining to heliostat components and controls as part of the U.S. Department of Energy (DOE), Heliostat Consortium (Heliocon) program. This work presents a detailed assessment of subcomponents, controls and wireless communications elements that comprise various designs of helisotats within concentrating solar power (CSP) installations. Additionally, this work also provides the results of an industry survey, intended to compliment the literature discussion, to provide a gap analysis of the primary technology and cost areas that need to be addressed to help improved to spur concentrating solar power (CSP) bankability. Although the results of the study determined several key areas for development, three strategic areas identified were: (1) the use of advanced composite materials to replace a need for expensive steel within the structure and mirror substrate, (2) employment of closed-loop controls for automated calibration, reduction of commissioning time and O&M hours, reduction of drive requirements, as well as overall cost reduction, and (3) the need for more Heliostat-centric codes and standards to facilitate engineering confidence in the development of new features, cost reductions, or other design iterations to be seamlessly introduced without optical performance problems.