bluuebunny/crossref_metadata_2025_split huggingface dataset:
Unlocking the Mysteries of Epicardial Adipose Tissue: Implications of Cardiometabolic Syndrome
Authors: Cacciapuoti Federico , Liguori Carlo , Nasti Rodolfo , Capone Valentina , Cacciapuoti Fulvio 
Published: August 2024

Abstract
Metabolic syndrome (MS) is a complex condition characterized by various factors, including abdominal obesity, high triglyceride levels, low high-density lipoprotein-cholesterol, high blood pressure, and elevated fasting blood sugar. Obesity, marked by the expansion of fat mass and increased fat cell production, is closely linked to MS. This review explores the role of adipose tissue (AT), particularly epicardial AT (EAT), in the development of MS and other cardiovascular complications. Notably, EAT, located around the heart and coronary arteries, is implicated in cardiovascular diseases such as coronary artery disease, atrial fibrillation, and heart failure through the production of proinflammatory cytokines. Emerging therapies, including glucagon-like peptide-1 receptor agonists and sodium-glucose co-transporter-2 inhibitors, have shown promise in reducing EAT thickness and improving cardiovascular outcomes. However, distinguishing visceral fat from subcutaneous fat in obese individuals remains a challenge, necessitating further research to develop targeted interventions. In conclusion, EAT plays a critical role in cardiovascular health, and ongoing studies are required to advance our understanding and develop precise interventions to mitigate its impact on cardiovascular diseases in at-risk individuals.
Stigma in steatotic liver disease: A survey of patients from Saudi Arabia
Authors: Alqahtani Saleh A. , Alswat Khalid , Mawardi Mohamed , Sanai Faisal M. , Abaakhail Faisal , Alghamdi Saad , Al-Hamoudi Waleed K. , Nader Fatema , Stepanova Maria , Younossi Zobair M. ,   on behalf of the Global NASH Council
Published: August 2024

Abstract

Background:
A recent name change of nonalcoholic fatty liver disease (NAFLD) or metabolic dysfunction-associated fatty liver disease (MAFLD) to metabolic dysfunction-associated steatotic liver disease was primarily driven by potential stigma associated with the terminology. This stigma can be different between patients and healthcare providers and differ according to geographic regions of the world. Our aim was to better understand stigma and disease burden among patients with NAFLD enrolled in the global survey from Saudi Arabia (SA).

Methods:
Members of the Global NASH Council created a 68-item survey about patients’ experience with NAFLD, covering history of stigmatization and discrimination due to the disease, various aspects of the disease burden [(Liver Disease Burden (LDB), 35 items, 7 domains], and perception of various diagnostic terms for NAFLD. Patients whose country of residence was SA were asked to complete the survey.

Results:
The survey was completed by 804 patients with NAFLD from SA. Of all enrolled patients, 17% ever disclosed having NAFLD/nonalcoholic steatohepatitis (NASH) to family/friends. The most commonly used term for the disease was “fatty liver” (96% used it at least sometimes, 79% frequently or always). There were 3.7% who reported experiencing stigma or discrimination (at least sometimes) due to obesity/overweight versus only 2.7% due to NAFLD. Female patients reported a history of stigmatization or discrimination more frequently than males: 5.9% versus 3.0% due to obesity (P = 0.06) and 5.4% versus 1.8% due to NAFLD (P = 0.01). There were 43% of patients who reported ever missing or avoiding a visit to a primary care provider due to NAFLD (48% male vs 28% female, P < 0.0001). The greatest social-emotional burden among patients with NAFLD (by LDB) was being or being identified as a person with liver disease (10% agree, 4% male vs 26% female) and feeling like they could not do anything about their liver disease (6.4% agree, 3% male vs 16% female). Regarding how patients perceived diagnostic terms, there were no substantial differences between “fatty liver disease”, “NAFLD”, “NASH”, and “MAFLD”.

Conclusion:
Stigmatization in terms of disease burden, disease-related stigma, and perception of various diagnostic terms are rarely observed in patients with NAFLD in SA. In comparison to male patients, female patients with NAFLD reported more commonly a history of stigmatization and discrimination and a significantly greater disease burden. The findings will help inform policymakers to develop programs to increase awareness and provide education about stigma related to NAFLD.
Effect of Media Composition on Biohydrogen Production from Fig (<i>Ficus carica</i>) by Dark Fermentation
Authors: Abibu W. , Kaya M. , Karadas Y. , Karapinar I. 
Published: August 2024

In this study, mesophilic batch fermentation experiments were conducted to investigate the effects of varying C/N ratios (25 -100) on biohydrogen production. The fermentable sugar was obtained from microwave hydrolyzed waste fig (Ficus carica). A control experiment without external nitrogen addition was also set-up to evaluate if the nitrogen content of hydrolyzed fig could sustain biohydrogen production. The highest cumulative hydrogen volume (861± 0.5 ml) and volumetric production (4.3 ± 0.3 L/Lreactor) were obtained at C/ N=50. The yields varied between 0.9 ± 0.21 and 1.1 ± 0.23 mol H2 mol-1 TSconsumed for C/N= 25-100. The highest production rates achieved were 11.5 ± 0.12 ml h-1 and 57.5 ± 0.14 ml L-1 h -1 at C/N=50. Thus, the best ratio in terms of substrate conversion to hydrogen is C/N=50 which can be evaluated as the nitrogen-sufficient condition. The nitrogen content of the hydrolyzed waste fig (control) was not sufficient for efficient biohydrogen production and external nitrogen addition is required to obtain a higher production rate. There were significant differences between the C/N ratio for cumulative hydrogen volumes, hydrogen production rate and volumetric hydrogen production rate.
Isolation, Characterization and Biodegradability Tests of Cellulase from Bacterium Obtained from the Soil of Agro Dumpsite
Authors: Odufuwa K.T. , Otuyemi K.M. , Fagbohunka B.S. , Ezima E.N. , Faponle A.S. , Itakorode B.O. 
Published: August 2024

The study investigated the waste biodegradation potential of cellulase produced by bacteria isolated from soil at an agro dumpsite, along with their physicochemical properties. The bacterium was identified as Bacillus subtilis and subjected to extracellular cellulase production via shaking flask fermentation. The production conditions such as pH, temperature, and incubation time were optimized using random surface methodology (RSM). The response was predicted by second-order polynomial model. In addition, the enzyme produced was partially purified, characterized, and explored in the biodegradation of agricultural waste products using standard methods. Cellulase yield in the experiment varied from 3.00 to 10.30 U/mL and under the optimum conditions of pH 7.0, 40 oC and 18 hr incubation time, the value for cellulase yield was 10.70 U/mL. The enzyme purification resulted in a specific activity of 3.3 Units/ mg of protein and 20 % yield. The Km and Vmax of the partially purified enzyme were 3.33 mg/mL and 52.0 U/mL respectively. The optimum pH and temperature of B. subtilis cellulase were at pH 5.0 and 50oC respectively. The inhibitory study showed that Na+ did not inhibit the activity of the enzyme while the enzyme activity was moderately inhibited by Mg2+, Sn2+ and Hg2+. Potassium ions (K+) strongly inhibited enzyme activity. The substrate specificity test showed that the enzyme was able to utilize other substrates. CMC, orange peel, pectin, pineapple peel and maize cob all showed 100% activity while rice husk and maize starch had an activity of 89 and 14 % respectively. The study concluded that response surface methodology (RSM) could be used to optimize bacteria cellulase production conditions and that the enzyme is suitable for various biotechnological processes such as waste management.
Dynamics of Foliar Application of Silver Nitrate on <i>Fusarium wilt</i> Severity, Growth and Fruit Yield of Tomato
Authors: Ganiyu S.A. , Popoola A.R. , Wahab O.Y , Imonmion J.E. , Yekini B.A. , Oke M.O. , Danbabuwa M.Y. 
Published: August 2024

Management of fungal diseases on crop plants has been towards developing safe and sustainable approaches that pose less danger to man and the environment. The study examined the foliar application of silver nitrate in screenhouse for the management of the Fusarium wilt of tomato. A completely randomized design was used for the experiment and replicated three times. The experiment consisted of a tomato variety (Roma round) and silver nitrate (AgNO3) at 10 ppm, 50 ppm, and 100 ppm. Untreated control (0 ppm) pots served as negative control while Carbendazim (2500 ppm) served as a positive control. Results revealed that tomato plants treated with silver nitrate at 100 ppm at 8th WAT had a severity index of 3.00, which was significantly lower than the 4.33 and 6.00 disease severity recorded for plants treated with 50, 10 and 0 ppm concentrations of silver nitrate, respectively. The highest harvested fruit yield (35.90 tons/ha) was recorded for plants treated with Carbendazim, followed by 32.59 tons/ha recorded for plants treated with 100 ppm silver nitrate, which were not significantly different from each other. However, both values were significantly different from 20.47, 0.40, and 0.31 tons/ha fruit yield recorded for plants treated with 50, 10, and 0 ppm silver nitrate concentrations, respectively. The results showed that silver nitrate at 100 ppm concentration can reduce Fusarium wilt infection on tomato which would consequently translate to fruit yield increase.
Tautological relations and integrable systems
Authors: Buryak Alexandr , Shadrin Sergey 
Published: August 2024

We present a family of conjectural relations in the tautological cohomology of the moduli spaces of stable algebraic curves of genus $g$ with $n$ marked points. A large part of these relations has a surprisingly simple form: the tautological classes involved in the relations are given by stable graphs that are trees and that are decorated only by powers of the psi-classes at half-edges. We show that the proposed conjectural relations imply certain fundamental properties of the Dubrovin-Zhang (DZ) and the double ramification (DR) hierarchies associated to F-cohomological field theories. Our relations naturally extend a similar system of conjectural relations, which were proposed in an earlier work of the first author together with Gu\'er\'e and Rossi and which are responsible for the normal Miura equivalence of the DZ and the DR hierarchy associated to an arbitrary cohomological field theory. Finally, we prove all the above mentioned relations in the case $n=1$ and arbitrary $g$ using a variation of the method from a paper by Liu and Pandharipande, this can be of independent interest. In particular, this proves the main conjecture from our previous joined work together with Hern\'andez Iglesias. We also prove all the above mentioned relations in the case $g=0$ and arbitrary $n$.Comment: v3: final journal version, 44 pages
Integrating mindfulness and physical activity for diabetes prevention and management: systematic review
Authors: Yusuf Ah , Nurhasan Nurhasan , Rahmatika Qory Tifani , Kinanti Rias Gesang , Aditya Ronal Surya , Sulistyana Caturia Sasti , Fauzi Abdul , Almutairi Reem Iafi , Kotijah Siti 
Published: August 2024

Background: Urgent need lies in the development of more effective and holistic interventions that encompass both the physical and psychological dimensions of diabetes. The aim of this study was to investigate the effectiveness of integrating mindfulness and physical activity in the prevention and management of diabetes. Method: The systematic review of existing literature aims to highlight the importance of a deeper understanding of the relationship between mindfulness and physically active activities in the context of diabetes prevention and managing. Result: The results of this systematic review highlight multiple beneficial outcomes, including improvements in psychological well-being and diabetes management, holistic care, parasympathetic activity, insulin resistance, stress reduction, self-management, and mindful eating. Conclusion: The findings advocate for the adjunctive use of mindfulness-based interventions like mindfulness based stress reduction (MBSR), MBCT, and MB-EAT in diabetes care, offering avenues to mitigate stress, bolster self management, and potentially augment diabetes care through enhanced self-efficacy, knowledge, and communication.
Keywords: Self-Management, Mindfulness, Insulin Resistance, Psychological Well-Being, Self Efficacy, Exercise, Aging
OPTIMALISASI PERAN KIP DENGAN MEDIA SOSIAL DALAM MENINGKATKAN PARTISIPASI PUBLIK DAN PENYELENGGARA DALAM PEMILU 2024
Authors: Armiadi  , Nurmayuli  
Published: August 2024

Pentingnya alat komunikasi dan informasi yang cepat dan tepat untuk mengatasi masalah dalam penyelenggaraan pemilu 2024, seperti fenomena yang terjadi ditengah masyarakat, banyaknya pemilih yang memilih tidak memakai hak memilihnya; dikarenakan merasa ada kecurangan dalam pemilu dan banyaknya berita hoax seputar pemilu. Sehingga membutuhkan penyuluhan berasal dari Komisi Indenpenden Pemilu (KIP) sebagi penyampaian informasi yang akurat, untuk menghindari atau mengantisipasi fenomena tersebut dengan penggunaan media sosial. Tujuan artikel ini ialah memberikan informasi bagaiaman peran media sosial sebagai alat komunikasi dan informasi dalam rangka peningkatan partisipasi penyelenggra dan masyakarat (publik) dalam pemilu 2024. Hasil analisis menujukkan KIP sebagai panitia penyelenggara harus melakukan sosialisi dan pengotimalan informasi dan keuangan. Hal itu memiliki alasan yaitu Pertama, persentase pengguna edia sosial yang tinggi di tengah masyarakat Indonesia, kedua, media sosial menjadi alat komunikasi yang mudah dan cepat dalam penyampaian informasi sosialisasi Pemilu yang tepat adan akurat. Ketiga, sebagai penangkal berita hoax seputar sosialisasi Pemilu, dan meningkatkan partisipasi publik dan kinerja penyelengara KIP (panitia tingkat kabupaten, kecamatan ataupun desa) dalam pemilu dengan adanya interaksi aktif dalam media sosial.
Timings, Reporting Procedures About Violence Incident and Encouragement to Report WPV Among Health Care Workers
Authors: Hassan Hameed  , Rafiq Ahmed Shahid  , Ejaz Rahim  , Asma Abdul Qadeer  , Rabia Mahmood  , Sara Bashir Kant  , Mudassar Mushtaq Jawad Abbasi  
Published: August 2024

Objective: To evaluate and gain insight about timings, reporting procedures and encouragement to report workplace violence events among HCW’s of Multan
Methodology: Using a World Health Organization (WHO) tool, a cross-sectional study was carried out at emergency department of hospital in Multan from June to August 2019. Quantitative data on various aspects of the workplace violence (WPV) amongst 164-universally-sampled healthcare workers was collected.
Results: There were 167 healthcare workers; 97 of them were men and 67 were women. 98 (60%) reported violence at some point in their employment. Almost half of the participants (44.5%) most frequently worked with children < 10 years, whereas 13.4% treat elder patients. Talking about worriedness about violence in current workplace, 22.6% subjects were very worried in comparison to 56% little bit worried. One third subjects in this study reported that physical violence incident happened during the morning shift and 1st day of week. All HCW’s said that there are procedures for reporting of violence at their workplace, they know how to use them & there is an encouragement to report WPV as well. 92.7% & 2.4% partakers said that encouragement was from colleague & management / employer respectively
Conclusion: Mostly, violence was reported at 1st working day of the week and there were reporting procedures and an encouragement to report those events as well. Local, state, and federal initiatives are required to modify policies in future to address workplace violence in the healthcare sector.
PENINGKATAN PRESTASI BELAJAR SISWA KELAS XI IPA-4 SMAN 1 CERME PADA PELAJARAN PPKN TENTANG SISTEM HUKUM DAN PERADILAN DI INDONESIA MELALUI METODE INQUIRI TERPIMPIN
Authors: Kusmiati Sri 
Published: August 2024

Demikian besar tujuan pembelajaran PPKn, tidak sebanding dengan prestasi belajar yang diraih para siswa kelas XI IPA-4 SMAN 1 Cerme Gresik tahun pelajaran 2021/2022. Pada ulangan harian tentang Sistem Hukum dan Peradilan di Indonesia, didapat nilai rata–rata kelas yang sangat rendah yaitu 55,4 dan ketuntasan belajar secara klasikal mencapai 41,7%. Hal ini menunjukkan bahwa ada 15 siswa dari 36 siswa sudah tuntas belajar. Maka, peneliti akan menerapkan metode inquiri terpimpin. Metode pembelajaran inquiri terpimpin adalah metode mengajar yang sangat erat hubungannya dengan memecahkan masalah (problem solving). Penelitian berlangsung di ruang kelas XI IPA-4 SMAN 1 Cerme Gresik, pada tanggal 7 Februari 2022 sampai 23 Mei 2022. Yang menjadi subjek penelitian adalah siswa kelas XI IPA-4 SMAN 1 Cerme Gresik tahun pelajaran 2021/2022, sebanyak 36 siswa. Dari hasil kegiatan pembelajaran yang telah di lakukan selama dua siklus, dan berdasarkan seluruh pembahasan serta analisis yang telah dilakukan dapat disimpulkan bahwa penerapan metode pembelajaran inquiri terpimpin memiliki dampak positif dalam meningkatkan prestasi belajar PPKn tentang Sistem Hukum dan Peradilan di Indonesia, yang ditandai dengan peningkatan aktivitas pembelajaran dalam setiap siklus, serta meningkatnya nilai rata-rata hasil post test. Pembelajaran PPKn tentang Sistem Hukum dan Peradilan di Indonesia melalui penerapan metode pembelajaran inquiri terpimpin diawali dengan memberikan tugas mendiskusikan salah satu permasalahan, diantaranya : 1). Sistem ketatanegaraan menurut UUD 1945. 2). Sistem ketatanegaraan menurut Konstitusi RIS. 3). Sistem ketatanegaraan menurut UUD Sementara 1950. Pada kegiatan pembelajaran selanjutnya, siswa diberi tugas mencari artikel sistem ketatanegaraan menurut UUD 1945 berikut penyimpangan yang pernah terjadi, sistem ketatanegaraan menurut Konstitusi RIS berikut penyimpangan yang pernah terjadi, serta sistem ketatanegaraan menurut UUD Sementara 1950 berikut penyimpangan yang pernah terjadi melalui kajian buku, internet dan sumber-sumber lain.
PENERAPAN METODE INQUIRY BASED LEARNING UNTUK PENINGKATAN HASIL BELAJAR MATEMATIKA TENTANG PELUANG DI KELAS IX-D SMPN 2 KUTOREJO
Authors: Suntai Bawon 
Published: August 2024

Pembelajaran matematika khususnya pada materi peluang, di kelas IX-D SMP Negeri 2 Kutorejo Mojokerto tahun pelajaran 2019/2020, mengalami banyak hambatan. Kurangnya kemampuan siswa kelas IX-D dalam memahami materi peluang dapat diketahui dari hasil penelitian awal yang dilakukan oleh guru matematika (peneliti). Dari 37 orang siswa di kelas IX-D yang terdiri dari 9 laki dan 28 perempuan, kemampuan dalam materi tersebut teridentifikasi sebagai berikut: (a) sangat baik sebanyak 7 orang atau 18,92%; (b) baik sebanyak 7 orang atau 18,92%; (c) cukup sebanyak 5 orang atau 13,51%; (d) kurang sebanyak 13 orang atau 35,14%; dan (e) sangat kurang sebanyak 5 orang atau 13,51%. Maka melalui penelitian tindakan kelas ini, peneliti akan menerapkan metode pembelajaran inquiry based learning. Penelitian ini dilaksanakan dengan rancangan penelitian tindakan kelas yang prosedur pelaksanaannya mengikuti prinsip dasar penelitian tindakan yang umum. Prosedur tersebut merupakan suatu proses siklus atau daur ulang. Setiap siklus meliputi planning (rencana), action (tindakan), observation (pengamatan), dan reflection (refleksi). Langkah pada siklus berikutnya adalah perncanaan yang sudah direvisi, tindakan, pengamatan, dan refleksi. Pelaksanaan penelitian ini dilaksanakan sebanyak dua siklus. Tiap siklus dilaksanakan dalam 2 kali pertemuan @ 2 jam pelajaran. Berdasarkan uraian pada bab IV, peneliti menarik simpulan bahwa prestasi belajar siswa kelas IX-D SMP Negeri 2 Kutorejo Mojokerto sebelum menggunakan metode inquiry based learning dikategorikan kurang dengan dengan prosentase 59,56%. Setelah menggunakan metode inquiry based learning dalam pembelajaran terjadi peningkatan prestasi belajar siswa kelas IX-D SMP Negeri 2 Kutorejo Mojokerto dengan kategori baik yaitu mencapai 75,80% pada siklus I, kemampuan tersebut meningkat pada siklus II mencapai prosentase 83,40%. Adapun tingkat keberhasilan belajar siswa pada siklus I adalah 80,67% meningkat menjadi 86,13% pada siklus II.
Launching the Career of William J. Tonesk of Schenectady, New York
Authors: Mazurkiewicz Anna 
Published: August 2024

Abstract
William J. Tonesk was born to a family of Polish immigrants who came from Russian and Austrian partitions of Poland. Born Władysław Jan Toniecki in Schenectady, New York, he can be traced in historical records using several last names: Tonski, Toniski, Tonick. While using his passion for Polish literature and theater as an advantage throughout his high school and college years, he invariably presented himself as an American. He settled for William J. Tonesk in 1932 as he entered Columbia University in New York. This article explores the opportunities available to the young man from Schenectady who skillfully navigated the ethnic advantage and native opportunity to spur his professional career. It also examines the support from Polish American organizations that was instrumental in keeping him intellectually and professionally engaged in the 1930s. Repeatedly, he multiplied the effects of the opportunities available to him, thus establishing a sound prequel to his professional career in the US intelligence establishment and diplomacy.
Efektivitas Pemberian Aromaterapi Lavender terhadap Kualitas Tidur pada Ibu Menopause di RT04/RW15 Kec. Baleendah Kab. Bandung Tahun 2023
Authors: Nurwiliani Lia , Nency Aprilya , Dewi Meinasari Kurnia 
Published: August 2024

Gangguan tidur merupakan salah satu gejala yang paling banyak dilaporkan oleh wanita menopause, Dampak gangguan tidur diantaranya adalah penurunan kualitas hidup, penurunan produktivitas kerja, peningkatan prevalensi kecemasan, depresi serta penyakit kardiovaskuler.(Proserpio et al., 2020) Perlu adanya upaya yang dilakukan bidan untuk mengatasi gangguan tidur pada menopause, pemberian essential oil Aromaterapi lavender merupakan salah satu cara untuk mengatasi gangguan tidur pada menopause. Tujuan penelitian ini adalah mengetahui Efektifitas Aromtherapi Lavender terhadap kualitas tidur menopause di RT04 RW 15 Kec. Baleendah tahun 2023. Karya penulisan ini disusun menggunakan metode Study Case Literature Review. Data diperoleh dengan cara mengukur kualitas tidur menggunakan kuisioner PSQI terhadap 2 orang ibu menopause dengan intervensi aromaterapi lavender pada salah satunya, kemudian di evaluasi sebanyak 3 kali yaitu hari ke 1, 4 dan 7. Didapatkan hasil penelitian yaitu, terdapat pengurangan skor PSQI yang artinya perbaikan kuallitas tidur pada kedua responden. Akan tetapi pada responden dengan intervensi aromaterapi lavender memiliki perbaikan kualitas tidur yang lebih banyak dengan hasil kualitas tidur pada hari ke 1, 4, dan 7 yaitu, buruk, cukup kemudian baik. Berbeda dengan responden 2 diketahui kualitas tidur, yaitu buruk, buruk dan cukup. Disarankan pada ibu menopause dengan gangguan tidur untuk menggunakan aromaterapi lavender