bluuebunny/crossref_metadata_2025_split huggingface dataset:
Statistical modeling of copper losses in the silicate slag of the sulfide concentrate smelting process
Authors: Savic Marija V. , Djordjevic Predrag B. , Mihajlovic Ivan N. , Zivkovic Zivan D. 
Published: September 2015

Abstract
This article presents the results of the statistical modeling of copper losses in the silicate slag of the sulfide concentrates smelting process. The aim of this study was to define the correlation dependence of the degree of copper losses in the silicate slag on the following parameters of technological processes: SiO2, FeO, Fe3O4, CaO and Al2O3 content in the slag and copper content in the matte. Multiple linear regression analysis (MLRA), artificial neural networks (ANNs) and adaptive network based fuzzy inference system (ANFIS) were used as tools for mathematical analysis of the indicated problem. The best correlation coefficient (R2 = 0.719) of the final model was obtained using the ANFIS modeling approach.
A very rare, petro-clival, neurothekeoma tumor. Case Report
Authors: Iacob G. , Tene Silvia , Iuga Mariana , Simion G. 
Published: September 2015

Abstract
Known as nerve sheath myxoma too, neurothekeoma are benign tumors, usually arise in the skin of the head, neck region and upper extremities, in young females. Cerebral neurothekeoma are very rare, a few cases were already described in the parasellar area, in the middle cranial and posterior fossa. We present a petro-clival neurotekoma. A 78-year-old male was admitted for two years left fronto-temporal headache completed in the last 6 months with left trigeminal V1 neuralgia, left facial hypoesthesia, diplopia, swallowing disorders for liquid foods, balance disorders. From his medical records we noticed: stage 2 chronic kidney disease, hypertension, prostate adenoma, dyslipidemia hypercholesterolemia. The MRI showed a macronodular petroclival mass in hiper T2, hipo T1, flair iso signal; normal cerebral angiography. The patient was operated on using a left retrosigmoid, retromastoidian approach. A 4/3/3 cm tumor, gray, encapsulated, soft consistency, partially cystic, less bleeding, attached to the dura, displacing the basilar artery and brain stem controlateral, encasing the trigeminal nerve. The tumor was totally removed with a good postop evolution. Six months follow up he had no more facial pain, but only persistant left facial hypoesthesia. Histologically the tumor had lobular appearance with spindle or stellate cells embedded in abundant myxoid background. The tumor cells were diffusely positive for S100, PGP9.5’, CD 34” positive in vessels, Ki67’positive in 5%. Cranial MRI performed one month after surgery did not show any residual tumor. Also known as nerve sheath myxomas, neurothekoma are rare benign tumors. For intracranial neurothekoma surgical indication is mandatory
Partial thrombosed parasagittal AVM, complete resection. Case report
Authors: Sandu Aurelia Mihaela , Gorgan M.R. 
Published: September 2015

Abstract
INTRODUCTION: Arteriovenous malformations (AVMs) are congenital lesions formed by a network of dysplastic vessels.
CASE REPORT: We report a case of a 63 years old man, admitted with seizures and headache. Imaging findings, angio-CT, angio-MR and angiography revealed a partially thombosed right parasagittal frontal AVM, with fully thrombosed associated flow-related aneurysm on the main arterial feeder. The patient underwent surgery and we performed total resection of the AVM. The particularity of this case is the rare possibility of outcome with regression of the vascular malformation.
CONCLUSIONS: Brain AVMs are evolutive lesions. Regression, through progressive thrombosis of the nidus is a rare possible outcome in brain AVMs. In thrombosed AVMs angiography is not reliable, and angio-CT and/or angio-MR are mandatory, in order to correctly evaluate nidus size and associated lesions. Symptomatic AVMs require surgery. Partial thombosed AVMs can be safely resected.
The impact of surgery in high grade gliomas - a literature review
Authors: Baritchii Adriana , Gubian A. , Florian St.I. 
Published: September 2015

Abstract
Malignant gliomas are aggressive brain cancers. After many decades of intensive research they represent a major cause of cancer related mortality and morbidity. Management of malignant gliomas is very difficult. None of the current treatments are curative. High grade gliomas are optimally treated with surgery followed by radiotherapy and chemotherapy. The impact of surgery on progression free survival and overall survival was a constant preoccupation and debate for decades among neurosurgeons. Different studies published in the last 25 years have provided evidence that the extent of resection of high grade gliomas can influence time to progression and median survival, although so far there is no class I prospective randomized trial to fully answer this question. Some of the most important studies are reviewed here. The modern neurosurgery relay on some tools that proved to be very helpful in guiding the surgeon to achieve the maximal tumoral cytoreduction with minimum impact on the brain’s eloquent areas. iMRI has been proved to be safe and became an important tool during tumor surgery, used alone or in conjuction with other important techniques: intraoperative neurophysiology, awake cortical mapping, 5-ALA fluorescence etc. Although so far the prognostic of high grade gliomas is still disappointing, further understanding of the biology of these tumors and a patient-tailored treatment could be the keys of finding a cure in the future.
Pedicle screw fixation for low lumbar burst fracture with grade 4 retrolisthesis without any neurological deficit
Authors: Patil Rahul Pramod , Jaiswal Gaurav , Gupta Tarun Kumar 
Published: September 2015

Abstract
Burst fractures of the spine account for 14% of all spinal injuries. Lower lumbar burst fracture with retrolisthesis is a rare presentation of traumatic cause. Management of this type of fracture are controversial and depends on plenty of factors like age of patient, type of injury, neurological deficit, associated comorbit injury. Here we are discussing a rarest case of traumatic burst fracture of L4 vertebrae with grade 4 retrolysthesis of L4 on L5 vertebrae with severe secondary canal stenosis and neurologically intact, which was manage with pedicle screw fixation.
Prevalence and determinants of depression and its association with quality of life in Traumatic Brain Injury (TBI) patients
Authors: Sharma Anand , Jain Akhilesh , Sharma Achal , Mittal R.S. , Gupta I.D. 
Published: September 2015

Abstract
Introduction: Traumatic brain injury (TBI) is a major cause of disability. Assessment and treatment of TBI typically focus on physical and cognitive impairments, yet psychological impairments represent significant causes of disability. Depression may be the most common and disabling psychiatric condition in individuals with TBI.
Objective: This cross-sectional study was design to investigate prevalence and risk factors of depression in Traumatic brain injury (TBI).
Material and method: The Group studied consists of 204 patients of mild and moderate TBI between 14-days to one-year post injury. Demographic characteristics of the participants were assessed on a self-designed semi structured performa. Interviews focused on assessment of severity of TBI, depression and quality of life (Qol) using GCS, PHQ-9 and WHOBREF-QOL respectively.
Results: Total 204 patients were included. 42.15% participants were found to have depression. None of the demographic variables were associated with depression except female sex, severity and time since injury. Moderate TBI patient (55.80%) had significantly higher occurrence of depression than the mild cases (44.2%). Patients with lesser duration (time since injury) of TBI had high incidence (50.2%) of depression compare to longer duration of TBI. Depressed patients also had poor Qol than those without depression in all domains except physical health domain. Neuroanatomical localization was also correlated with depression. Cerebral contusions were the most common (44.24%) lesions associated with depression.
Conclusion: Depression is commonly associated, yet under diagnosed clinical entities in head injury and have tremendous impact in overall outcome measures. Every patient of head injury warrants psychiatric evaluation and concomitant treatment if required to ensure the attainment of not only neuroanatomical intact but overall productive and qualitative life vindicating the holistic and multidisciplinary treatment approach.
THE INFLUENCE OF PAROXETINE ON THE PHARMACOKINETICS OF ATOMOXETINE AND ITS MAIN METABOLITE
Authors: Todor Ioana , Popa Adina , Neag Maria , Muntean Dana , Bocsan Corina , Buzoianu Anca , Vlase Laurian , Gheldiu Ana-Maria , Chira Ruxandra , Briciu Corina 
Published: September 2015

Background and aims. To evaluate the effects of paroxetine on the pharmacokinetics of atomoxetine and its main metabolite, 4-hydroxyatomoxetine-O-glucuronide, after coadministration of atomoxetine and paroxetine in healthy volunteers.Methods. 22 healthy volunteers, extensive metabolizers, took part in this open-label, non-randomized, clinical trial. The study consisted of two periods: Reference, when a single oral dose of 25 mg atomoxetine was administrated to each subject and Test, when 25 mg atomoxetine and 20 mg paroxetine were coadministered. Between the two periods, the volunteers received an oral daily dose of 20-40 mg paroxetine, for 6 days. Atomoxetine and 4-hydroxyatomoxetine-O-glucuronide plasma concentrations were determined within the first 48 hours following drug administration. The pharmacokinetic parameters of both compounds were assessed using a non-compartmental method and the analysis of variance aimed at identifying any statistical significant differences between the pharmacokinetic parameters of atomoxetine and its main metabolite, corresponding to each study period.Results. Paroxetine modified the pharmacokinetic parameters of atomoxetine. Cmax increased from 221.26±94.93 to 372.53±128.28 ng/mL, while AUC0-t and AUC0-∞ also increased from 1151.19±686.52 to 6452.37±3388.76 ng*h/mL, and from 1229.15±751.04 to 7111.74±4195.17 ng*h/mL respectively. The main metabolite pharmacokinetics was also influenced by paroxetine intake, namely Cmax, AUC0-t and AUC0-∞ decreased from 688.76±270.27 to 131.01±100.43 ng*h/mL, and from 4810.93±845.06 to 2606.04±923.88 and from 4928.55±853.25 to 3029.82 ±941.84 respectively.Conclusions. Multiple-dose paroxetine intake significantly influenced atomoxetine and its active metabolite pharmacokinetics, causing a 5.8-fold increased exposure to atomoxetine and 1.6-fold reduced exposure to 4-hydroxyatomoxetine-O-glucuronide.
GENETIC DIVERSITY AND POPULATION STRUCTURE OF MANDAR BESAR (Porphyrio porphyrio) iNHABITING JAVA WETLANDS
Authors: Subrata Sena Adi 
Published: September 2015

<p>Despite the occurrence of a massive agricultural landscape change in Java, very few reliable studies evaluate its genetic consequence for impacted wildlife species. This study reported the genetic diversity of the Mandar besar (Porphyrio porphyrio) in the modified landscape of Java as a backdrop for such an evaluation. Aim of this study was to estimate genetic diversity and genetic structure of the species. I collected eighty-eight blood samples from five a-priory populations (Demak, Jombor, Kendal, Pagak, and Nawan) and genotyped them at ten selected microsatellite loci to estimate allelic richness (R) and expected heterozygosity (He), fixation index (FST) and genetic clusters (K). DNA was isolated using a commercial kit (Invitrogen) and amplified using touch-down polymerase-chain-reaction technique. Allele length was estimated using an automatic sequencer. Pre-analysis showed that all selected loci have null alleles frequency less than 0.2, successful amplification rate more than 80%, no significant linkage between loci and no deviation from HWE. Further analysis employing GDA and FSTAT showed that Demak population has richest genetic diversity in term of R, meanwhile Jombor was the poorest population. Analysis of population structure employing FSTAT and STRUCTURE showed that the population was likely structured into four subpopulations, as showed by FST (0.085; P&lt;0.05) and K=4 (ln probability -1725.2+3.92). This study might reveal that genetic diversity and population structure of Mandar besar in Java were still in common level as compared to other aquatic bird species.</p><p><br /><strong>Keywords </strong>:Swamphen, bird, richness, genetic, wetlands</p>
Atrial fibrillation and chronic kidney disease: focus on rivaroxaban
Authors: Barrios Vivencio , Górriz José Luis 
Published: September 2015

Renal insufficiency increases the risk of stroke and bleeding in atrial fibrillation patients. Although vitamin K antagonists reduce the risk of stroke in patients with moderate renal dysfunction, this observation is less clear in patients with renal impairment. Moreover, the risk of bleeding with vitamin K antagonists increases as renal function worsens. Maintaining international normalized ratio values within therapeutic targets is more difficult in patients with renal dysfunction, and those agents may cause warfarin-related nephropathy and vascular calcification. Rivaroxaban is the only nonvitamin K oral anticoagulant with a dose specifically tested in patients with moderate renal insufficiency. Rivaroxaban is effective for the prevention of stroke in atrial fibrillation patients with moderate renal dysfunction, with a lower risk of intracranial and fatal bleeding.
A Comparison Of The Wind Spectrum According To Different Methods - An Original Project Of A Building On A Cliff In Gdynia
Authors: Zielińska M. , Zarychta K. 
Published: September 2015

Abstract
The article presents numerical simulations of the dynamic wind loads on the structure of a building designed on a cliff in Gdynia. The results obtained from the two methods: Davenport’s and Karman’s are compared. The results allowed a comparison of the two methods, and they provided an answer to the question how a construction, designed in such an unusual condition of a cliff behaves under the influence of the gusting wind. The wind spectrum is presented and compared in both directions: of the X-axis and of the Y-axis. The dynamic calculations are carried out in the Abaqus software. The conducted numerical analyses compare the displacements in two points - at half height of the building and at the top - obtained by the two methods.
Compressed Sensing Of Complex Sinusoids Off The Grid
Authors: Ping Cheng , Liu Shi , Jiaqun Zhao 
Published: September 2015

Abstract
To solve off-grid problem in compressed sensing, a new reconstruction algorithm for complex sinusoids is proposed. The compressed sensing reconstruction problem is transformed into a joint optimized problem. Based on coordinate descent approach and linear estimator, a new iteration algorithm is proposed. The results of experiments verify the effectiveness of the proposed method.
Textual meaning and its place in a theory of language
Authors: Jeffries Lesley 
Published: September 2015

Abstract
Following the development of a framework for critical stylistics (Jeffries 2010) and the explication of some of the theoretical assumptions behind this framework (Jeffries 2014a, 2014b, 2015a, 2015b), the present article attempts to put this framework into a larger theoretical context as a way to approach textual meaning. Using examples from the popular U.S. television show, The Big Bang Theory, I examine the evidence that there is a kind of textual meaning which can be distinguished from the core propositional meaning on the one hand and from contextual, interpersonal meaning on the other. The specific aim, to demonstrate a layer of meaning belonging to text specifically, is set within an argument which claims that progress in linguistics can better be served by adherence to a rigorous scientific discipline.
Effect of Initial Porosity on Material Response Under Multi-Axial Stress State for S235JR Steel
Authors: Kossakowski P.G. 
Published: September 2015

AbstractThe effect of the initial porosity on the material response under multi-axial stress state for S235JR steel using the Gurson-Tvergaard-Needleman (GTN) material model was examined. Three levels of initial porosity, defined by the void volume fraction f0, were considered: zero porosity for fully dense material without pores, average and maximum porosity according to the metallurgical requirements for S235JR steel. The effect of the initial porosity on the material response was noticed for tensile elements under multi-axial stress state defined by high stress triaxiality σm/σe = 1.345. This effect was especially noticeable at the range of the material failure. In terms of the load-bearing capacity of the elements, the conservative results were obtained when maximum value of f0 = 0.0024 was used for S235JR steel under multi-axial stress state, and this value is recommended to use in the calculations in order to preserve the highest safety level of the structure. In usual engineering calculations, the average porosity defined by f0 = 0.001 may be applied for S235JR.
Nonlinear Static Analysis of an Asphalt Concrete Core Dam dor Comparison of Three Constitutive Models
Authors: Hong Z. , Hongyan Z. , Jianke D. 
Published: September 2015

AbstractThe goal of this work is to compare different constitutive models in the nonlinear static characteristic analysis of asphalt concrete core dams. The Duncan E- μ model, Duncan E-B model and double-yield-surface model are three major constitutive models in the nonlinear static prediction of earth-rockfill dam. In this paper, an earth-rock fill dam with asphalt concrete core-wall in an actual hydraulic engineering is employed to compare the three models. The finite element model of the core-wall dam is proposed. Nonlinear static analysis of the dam is carried out and the static characteristics are obtained to study the differences generated from different constitutive models. Numerical results show that both the stress extremum and the stress distribution of dam body with three different models are coincident one another. In the deformation analysis of dam body and core-wall, the maximum values of sedimentation with the Duncan E-μ model and the Duncan E-B model, which are greater than the value with double-yield-surface model, are close to the practical test data though the deformation distributions with three models are in good agreement. But, the analysis results of core-wall stress with double-yield-surface model are proper and more reasonable than the other models.
Tendinopathy: Update on Pathophysiology
Authors: Scott Alex , Backman Ludvig J. , Speed Cathy 
Published: September 2015

Synopsis Tendinopathy has become the accepted term to describe a spectrum of changes that occur in damaged and/or diseased tendons. Over the past 2 decades, there have been new insights into tendon pathophysiology of relevance to clinicians, including (1) better characterization of the overuse injury process and the resultant structural and functional disruption in chronically painful tendons, (2) improved understanding of the pathomechanics associated with chronic tendon injury, and (3) greater knowledge about the influence of lifestyle factors and drugs on tendon pathology. The implications of these new insights are discussed. J Orthop Sports Phys Ther 2015;45(11):833–841. Epub 21 Sep 2015. doi:10.2519/jospt.2015.5884
Patellar Tendinopathy: Clinical Diagnosis, Load Management, and Advice for Challenging Case Presentations
Authors: Malliaras Peter , Cook Jill , Purdam Craig , Rio Ebonie 
Published: September 2015

Synopsis The hallmark features of patellar tendinopathy are (1) pain localized to the inferior pole of the patella and (2) load-related pain that increases with the demand on the knee extensors, notably in activities that store and release energy in the patellar tendon. While imaging may assist in differential diagnosis, the diagnosis of patellar tendinopathy remains clinical, as asymptomatic tendon pathology may exist in people who have pain from other anterior knee sources. A thorough examination is required to diagnose patellar tendinopathy and contributing factors. Management of patellar tendinopathy should focus on progressively developing load tolerance of the tendon, the musculoskeletal unit, and the kinetic chain, as well as addressing key biomechanical and other risk factors. Rehabilitation can be slow and sometimes frustrating. This review aims to assist clinicians with key concepts related to examination, diagnosis, and management of patellar tendinopathy. Difficult clinical presentations (eg, highly irritable tendon, systemic comorbidities) as well as common pitfalls, such as unrealistic rehabilitation time frames and overreliance on passive treatments, are also discussed. J Orthop Sports Phys Ther 2015;45(11):887–898. Epub 21 Sep 2015. doi:10.2519/jospt.2015.5987
Concordance in the interpretation of PET after chemotherapy in advanced stage Hodgkin lymphoma
Authors: Kuhnert G. , Haverkamp H. , Fuchs M. , Kahraman D. , Eich H.-T. , Kriz J. , Baues C. , Nast-Kolb B. , Bröckelmann P. J. , Borchmann P. , Drzezga A. , Engert A. , Dietlein M. , Kobe C. 
Published: September 2015

SummaryThe aim was to analyze the degree of agreement between the central review panel and the local PET interpretation within the HD15 trial and its impact on subsequent treatment and progression free survival. Patients, methods: The analysis set consisted of 739 patients with residues ≥ 2.5 cm after 6 or 8 cycles of BEACOPPesc from the HD15 trial performed by the German Hodgkin Study Group. The recommendation for or against further radiotherapy was based on the central [18F]FDG-PET interpretation. Central PET interpretation was compared to the local PET interpretation and concordance was measured using Cohen's Kappa coefficient. Prognostic impact of the analysis of concordance between local and central PET interpretations was evaluated using progression free survival (PFS); groups were compared with the log rank test. Results: The central panel rated 548 of 739 patients (74%) as PET negative. Of these, 513 were also rated as PET negative in the local PET interpretation. PET positivity was seen by central reviewers in the remaining 191 patients (26%), in concordance with local reviewers in 155 cases. Even though substantial agreement was found (Cohen's Kappa 0.81), the interpretation of the central PET review panel led to a different therapeutic recommendation in 71/739 (10%) patients. PFS was equally high in groups in which the therapeutic regime had been changed on the basis of the central panel decision. Conclusion: High concordance is found between local and central reviewers with regard to PET interpretation in residual tissue after intense chemotherapy. The existence of the central PET review panel allows the identification of additional patients as PET negative so that radiotherapy can be safely omitted (35 of 548 patients = 4.7%).