bluuebunny/crossref_metadata_2025_split huggingface dataset:
2012 – Patients’ Experiences Of Medication For Anxiety Disorders
Authors: Igoumenou A. 
Published: July 2013

Background to the studyAnxiety disorders are abnormal states in which the most noticeable features are mental and physical symptoms of anxiety. They are of the most common psychiatric disorders in the general population with the lifetime prevalence approaching a 21%.The evidence based medicine lacks research on patients’ experience of medication for psychiatric disorders, especially of medication for anxiety disorders.This research involves patients referred to secondary care because of their anxiety symptoms and diagnosed as suffering with anxiety disorders.AimsTo illuminate the subjective experiences of patients diagnosed with anxiety disorders and their experience of taking medication. Therefore qualitative methodology was appropriate.ParticipantsAll the potential participants in two Mental Health Trusts in the UK were informed about the research from their consultant psychiatrist or care coordinator if different, and provided with an information sheet. In depth interviews were used to explore patients experiences and phenomenological approach to analyse the data.FindingsThe patients we interviewed presented with a range of anxiety disorders. There were participants that suffered from generalized anxiety disorder, others with panic disorder, obsessive compulsive disorder, agoraphobia or social phobia. Furthermore, the pharmacological treatment they were receiving varied. The overall treatment varied as treatment with medication was combined with any talking therapy or other support.In this presentation we share some of our patients’ feelings and thoughts about living with an anxiety disorder, their attitudes about the chosen treatment, their subjective perceptions about their medication and their perceptions around the effectiveness of such a treatment.
2039 – Multidimensional Scaling Analysis Of The Association Of Snps Related 5-htr2a Signal Pathway And The Phenotype Characteristics Of Major Depression In Chinese Han
Authors: Yang K. , Li H. 
Published: July 2013

ObjectiveOur aim was to explore the possible association between four SNPs related with 5-HTR2A signal pathways and phenotype characteristics of major depressive disorder (MDD) in Chinese Han.Methods194 patients with recurrent major depressive episodes were from Chinese Han origin. 4 SNPs were detected with LDR (ligase detection reaction). The multidimensional scaling analysis was use for testing the association between different genotypes of four SNPs (5-HTR2A rs6311, Gβ3 rs5443, ADCY9 rs2230739 and PDE1A rs1549870 related with 5-HT2A signal pathway) and phenotype characteristic of MDD.ResultsThe multidimensional scaling illustrated: rs6311CC, rs5443CC and rs1549870GG with the certainly-existed fundamental symptom 2 were in the same zone; rs6311CC and accessory symptoms 7, and rs6311CC and depressive episode with psychotic symptoms and repeated episodes are in the same zone. The results showed rs6311CC had a close correlation with depressive symptoms.ConclusionsIt is concluded that rs6311 may be the functional point of the 5-HT2A gene in MDD; It is presumed that different genotypes of rs5443 and rs2230739 can modulate the second message signal pathways in MDD.
2075 – Prevalence Of Mental Disorders Among Prisoners In The State Of são Paulo - Brazil
Authors: Andreoli S.B. , Santos M.M. , Quintana M.I. , Ribeiro W.S. , Blay S.L. , Taborda J.G.V. , Mari J.J. 
Published: July 2013

Epidemiological studies conducted with prisoners in several countries have shown a high prevalence of mental disorders.ObjectiveTo determine the prevalence of psychiatric disorders in the prison population in the State of São Paulo, Brazil.MethodsThrough stratified random sampling, 1,192 men and 617 women prisoners were evaluated for the presence of psychiatric disorders by the Composite International Diagnostic Interview, 2.1 version, according to definitions and criteria of International Classification of Diseases (ICD-10). The prevalence estimates of mental disorders and their respective 95% confidence intervals were calculated and adjusted for sample design through complex sample analysis.ResultsLifetime and 12-month prevalence rates differed between genders. Lifetime and 12-month prevalence of any mental disorder was, respectively, 68.9% and 39.2% among women, and 56.1% and 22.1% among men. Lifetime and 12-month prevalence of anxious-phobic disorders was, respectively, 50% and 27.7% among women and 35.3% and 13.6% among men, of affective disorders was 40% and 21% among women and 20.8% and 9.9% among men, and of drug-related disorders was 25.2% and 1.6% among women and 26.5% and 1.3% among men. For severe mental disorders (psychotic, bipolar disorders, and severe depression), the lifetime and 12-month prevalence rates were, respectively, 25.8% and 14.7% among women, and 12.3% and 6.3% among men.ConclusionsThis study, which was performed with a representative prison population, showed high rates of psychiatric disorders among men and women. Epidemiological studies on mental health needs of prisoners are crucial for planning and development of appropriate health care programs for specific prison populations.
2095 – The Portuguese Frost Mutidimensional Perfectionism Scale And Mood States In Portuguese College Students
Authors: Amaral A.P. , Soares M.J. , Pereira A.T. , Bos S.C. , Marques M. , Valente J. , Nogueira V. , Macedo A. 
Published: July 2013

IntroductionPerfectionism has been a topic of increased interest in recent years. Findings from the literature have shown that perfectionism is associated in the development and maintenance of a wide range of psychopathological conditions.Objectives/aims1)to analyze the psychometric properties of the Portuguese version of the Frost Multidimensional Perfectionism Scale (FMPS);2)to explore the associations between perfectionism dimensions and positive/negative affectivity.Methods217 students from two Portuguese Universities filled in the FMPS and the Profile of Mood States (POMS). A subgroup (n=166) completed a retest of the FMPS with a four weeks interval.ResultsScale reliability was good (Cronbach alpha = .857). Corrected item-total correlations ranged from .019 and .548, and were higher than .2 for most of the items. Test-retest reliability suggested a good temporal stability for FMPS total score (r=.765). A principal component analysis with Varimax rotation was performed and based on Scree plot, two robust factorial structures were suggested (four and six factors). The more maladaptive dimensions of perfectionism were significantly and positively associated with negative affect and negatively associated with positive affect. Depression and anxiety/hostility dimensions are both positively associated with concern over mistakes (respectively, r=.338, r=.360, p< .01), parental criticism (respectively, r=.180, r=.254, p< .01) and doubts about actions (respectively, r=.312, r=.189, p< .01). An unexpected result was the positive association with personal standards dimension (respectively, r=.178, p< .05; r=.204, p< .01).ConclusionsThe Portuguese version of FMPS showed good reliability and internal consistency. The perfectionism personality trait is associated with mood states.
2110 – Changes In Intellect Of War Veterans With Developed Ptsd
Authors: Pavlović S. , Hasanović M. , Kravić-Prelić N. 
Published: July 2013

IntroductionThe previous neuropsychological studies have pointed to a significant understanding of the neurobiological correlates of Post Traumatic Stress Disorder with deficits in the functions of the intellect.AimTo establish the existence of intellectual changes in war veterans with developed PTSD and their relationship to PTSD.MethodsWar veterans are divided into two groups: Group A, war veterans with PTSD and “B” groups, veterans without PTSD. Were used:-Wechsler's Adult Intelligence Scale (WB-F2)-Trauma Questionnaire (UT-PTSD)Questionnaire-socio-biographical data promjena u intelektualnom funkcionisanju.ResultsThe severity of stress and severity of post-traumatic stress disorder is directly associated with the intellectual functions. War veterans, who had more severe traumatic experience, with a strong and destructive PTSD compared to veterans without PTSD had significantly lower ratio of general, verbal and non-verbal intelligence quotient of mental efficiency, a high level of mental deterioration with significantly pronounced oscillations in intratest and insidetest variability. Veterans with PTSD showed significantly lower scores in the immediate memory capacity, efficient attention, concentration under conditions of mental activity, visual perceptual skills predicted exactly bit of trivial things, of associative elasticity of thinking and short-term learning abilities.ConclusionsThese results suggest that deficits in the intellect, are not primarily the result of low intelligence, of premorbid states, but it occurs under the devastating impact of PTSD, which influencing changes in certain centers in the brain and changes in intellectual functioning.
2113 – Self-esteem And Person-centered Therapy: a Pilot Study With Older Adults
Authors: von Humboldt S. , Leal I. 
Published: July 2013

ObjectivesA higher SE is suggested by a reduced difference between ideal and real self. The present pilot study was designed to investigate if a brief eight-session individual person-centered therapy (PCT) intervention on older adults can promote their self-esteem (SE), as compared with a control group (waiting list). We hypothesized that participants randomized to PCT would report improvements in SE from pre- to post-intervention compared tocontrol group.MethodWe recruited 81 persons aged between 65-82 years (M=71.9 SD=4.77) and randomized 40 to PCT and 41 to control group. Measures were completed, including demographics and the Self-esteem Scale (SES) at the baseline, post-treatment and at the 12-month follow-up.ResultsFindings indicated that individual PCT with older adults may improve their SE. The difference between ideal self and real self, evidenced at follow-up (M=1.251, SD=.524) by the participants who had undergone PCT, was significantly lower (41.3%) in comparison to the baseline score (M=2.131, SD=.799). Significant differences between the intervention group and the control group were found in the post- intervention (F(1) = 34.939, p < 0.01) and follow-up (F(1) = 34.595, p < 0.01). During these three assessments there were no significant differences in the waiting list participants. In addition, results revealed no significant between group differences in any socio-demographic variable (P's>.05) in t1, t2 and t3.ConclusionsResults suggest that PCT is beneficial for improving SE. Clinical practice and health care context may benefit from including PCT as an important component for reducing health disparities and for aging well.
2132 – Clinical And Neuropsychological Predictors Of Global Functioning In Paranoid Schizophrenia
Authors: García-Cabeza I. , Vicente I. , Sánchez Ayuso M.J. , Laorden A. , De Portugal E. 
Published: July 2013

IntroductionSchizophrenia is a worldwide public health problem that exacts enormous personal and economic costs. Schizophrenic patients often have difficulties to care by themselves and need from family and community support, including invalidity benefits.Objective and aimDetermine clinical and neuropsychological factors which predict global functioning and incapacity in paranoid schizophrenia.Methods40 paranoid schizophrenic outpatients (DSM-IV TR) were evaluated. Global functioning and incapacity was assessed with the DAS (Disability Assessment Schedule). Sociodemographic and clinical data were collected using a questionnaire including: age, gender, years of education and premorbid IQ (National Adult Reading Test), illness onset and triggers, admissions, adherence (Compliance Rating Scale), pharmacological treatment and drug abuse. In addition, psychopathology was assessed with PANSS, depressive symptoms’ with the Beck Inventory, insight with SUMD and cognitive functioning with a wide neuropsychological battery of tests which assessed attention, executive functions, verbal and working memory and social cognition.T-tests and chi-square analyses were used to explore binary or categorical variables and Pearson correlation coefficient for quantitative scales. A stepwise multiple regression analysis was used to predict DAS.ResultsDAS was correlated to positive (χ2 = .415; p = .008) and negative symptoms’ (χ2 = .530; p = .000), insight (χ2 = .519; p = .000) and executive functioning (χ2 = -.335; p = .035).The multiple regression analysis revealed that insight and negative symptoms’ predicted disability (R2 = .417).ConclusionsPsychological and psychosocial interventions that increase insight and improve negative symptoms’ should be included in a comprehensive treatment of schizophrenia to prevent disability. Future research on antipsychotics should be addressed to improve negative symptoms’.
2137 – Adaptive Behavior Of Family In Schizophrenia
Authors: Gutkevich E. , Semke A. , Dmitrieva E.G. 
Published: July 2013

Schizophrenia is a chronic disease resulting in disability, disturbance of adaptation in patient and his/her family.ObjectiveAnalysis of characteristics of adaptation based on authors’ many-level model of family functioning.Materials and methodsIdentification of quality of life of mental health care users, FACES-3, scales of prognosis of compliance in psychiatry (Lutova N. B. et al., 2007) and MARS. We have examined 152 schizophrenic patients (ICD-10 F2.0) and 38 their relatives.ResultsQuality of life of patients and relatives is affected; family are characterized by schizophrenic patients as a whole as balanced and middle-balanced in 82,35% of cases, as imbalanced - in 17,65%. Relatives of patients define families as balanced in 27,3%, as middle-balanced - in 54,5%, as imbalanced - in 18,2%. There are more middle-balanced families according to rating of probands and lesser balanced than relatives’ ratings. Imbalanced families are found almost with equal frequency. During the first hospitalization the insight of necessity of maintenance therapy, in opinion of patients, was found only in 27,6%; there was insight but they did not adhere recommendations of the doctor - 49,0%; there was not insight regarding meaning of doctor's prescription and they did not adhere doctor's recommendations - 23,4%. In the first year after the first hospitalization to psychiatric institution 55,0% persons have been re-hospitalized, out of them with non-compliance - 42,0%.ConclusionTraits of adaptive behavior of families in schizophrenia have been revealed.
2139 – Overprotective Parenting And Anxiety Of Children Presented At Albanian Child And Adolescent Psychiatry Clinic
Authors: Skendi V. , Alikaj V. , Spaho E. , Suli A. 
Published: July 2013

IntroductionMany children experience severe anxiety symptoms that lead to impairment in daily functioning (Albano, Chorpita, & Barlow, 2003). Anxiety disorders are among the most common psychiatric problems experienced by children and they appear to remain stable and problematic for many youngsters throughout childhood and adolescence. About 13 of every 100 children and adolescents ages 9 to 17 experience some kind of anxiety disorder; girls are affected more than boys. Various parenting styles have been associated with the development of a wide range of anxiety disorders.AimsThis study will look at correlations between parenting styles and symptoms among children with symptoms of anxiety disorders, at the Child/Adolescent Clinic of Psychiatry at University Hospital Center “Mother Teresa”.MethodsFamilies participating in this observational study completed different parent and child questionnaires during the first study session. The child questionnaires asked for information regarding the child's feelings and family interactions. Parent questionnaires asked for information about their own personal feelings as well as the child's feelings, symptoms, and behaviors. Age range was between 6 to 17 years, 58% of them was female. Exclusion criteria were mental retardation, current or past diagnosis of autistic spectrum disorders, current or past diagnosis of psychotic disorders.ResultsThere was a significant statistical correlation between overprotective parenting and number, intensity and severity of anxiety symptoms.ConclusionsResults of this study may contribute to the future treatment of children with anxiety disorders.
2145 – Importance Of The Collaborative Activities For The Development Of The Psychiatric Association Of Bosnia-herzegovina
Authors: Račetović G. , Pajević I. , Hasanović M. 
Published: July 2013

IntroductionNational association of experts dealing with psychiatry in our country named Psychiatric Association of Bosnia- Herzegovina (PABH) was formally started with its work on March 17th 2008, as the first national associations in the post-war Bosnia-Herzegovina (BH). Since 2009 has been actively promoted and profiling as one of the best organized professional associations in BH. Recognition on the international level and the active role of the PABH substantially achieved in 2010 in the World (WPA), and from 2011 in European (EPA) Psychiatric Association. The Third Congress of Psychiatrists of BH with international participation is the first in a series of future Congresses organized by PABH with the full support provided by EPA and WPA.AimTo show importance of the roles of EPA and WPA for the future PABH achievements.MethodsA retrospective review of the significance of the PABH collaboration with major psychiatric association both nationally and internationally through the documentation and archives of the PABH development.ResultsThe PABH is included in major psychiatric events in the country (active participation in the organization, logistics and scientific programme) and had strong collaboration with EPA and WPA, particularly on the national Congress in Tuzla 2012.ConclusionsThe PABH is the leading BH psychiatric association, an active member of the most important international organizations, with a continuous increase of the number of members who recognize the importance, relevance and quality of the PABH and further progress in its development and tendencies to harmonize psychiatric practice in the country and internationally.
2165 – Clinical Study On The Efficacy And Tolerability Of Escitalopram In Patients Diagnosed With Social Anxiety
Authors: Ionescu D. 
Published: July 2013

BackgroundSocial anxiety disorder represents a substantial public health problem because is a relative common mental disorder and has a high prevalence and lifelong chronicity. The fact that serotonergic agents is considered to be effective for its treatment suggests that patients may have an abnormal serotonergic neurotransmission. Selective serotonin reuptake inhibitors are effective in the treatment of social anxiety disorder and are currently perceived as the pharmacotherapy of choice.AimsWe investigated the efficacy and tolerability of escitalopram in the treatment of generalised social anxiety disorder.MethodPatients with generalised social anxiety disorder were randomised to receive placebo (n = 61) or10-20 mg escitalopram (n = 60) in a 12-week, double-blind study. The primary outcome measure was the mean change from baseline to last assessment in the Liebowitz Social Anxiety Scale (LSAS) total score.ResultsThe study showed a statistically superior therapeutic effect for escitalopram compared with placebo on the LSAS total score (p = 0.005).There were significantly more responders to treatment for escitalopram than for placebo (68% v. 28%; p < 0.005). The clinical relevance of these findings was supported by significant reduction in the work and social components of the Sheehan Disability Scale and by the good tolerability of escitalopram treatment.ConclusionsThese data suggest that escitalopram was efficacious and well tolerated in the treatment of social anxiety disorder. Further studies are needed on larger groups of patients to certify these results.
2168 – A Novel Mutation Of The Alpha Galactosidase Gene Linked With Fabry Disease And Therapy-resistant Depression
Authors: Weber S.K. , Muehlbacher M. , Egger C.L. , Geretsegger C. , Stuppaeck C. 
Published: July 2013

IntroductionFabry disease (FD) is an X- chromosome linked recessive glycolipid storage disease caused by deficient activity of the lysosomal enzyme Alpha Galactosidase A, resulting in progressive accumulation of aberrant catabolites like Globotriaosylsphingosin (lyso-Gb3) in vulnerable cells. The disorder can affect multiple organ systems including the central nervous system. A high proportion of patients with FD are at increased risk of developing neuropsychiatric symptoms.Materials and methodsA 56 year old female inpatient suffering from treatment resistant recurring depression with psychotic symptoms for a period of over two decades was diagnosed with asymptomatic hypertrophic cardiomyopathy in a routine health checkup. The incidental finding lead to an elaborate diagnostic work-up including genetic testing for FD as a possible cause.ResultA novel, hitherto undescribed mutation in the Alpha Galactosidase Gene (c.1025.1027delGAC) affecting enzyme activity was detected. In addition, lyso-GB3 concentration was increased above the normal level, in concordance with the diagnosis of FD.ConclusionIn this patient, undiagnosed FD associated with a novel mutation of the Alpha Galctosidase Gene may have caused predominantly psychiatric symptoms and contributed to therapy resistance.
2183 – Comparative Psychometric Analysis The Vascular, Traumatic And Epileptic Dementia
Authors: Verbenko V.A. , Malev A.L. , Zakharova A.N. 
Published: July 2013

IntroductionThe cerebrovascular disorders, traumatic brain injury and epilepsy lead to the development of dementia, which requires a psychometric verification of cognitive disorders.ObjectivesIn patients with dementia due to vascular brain diseases, traumatic brain injury and epilepsy was analyzed psychometric indicators of cognitive impairment.AimWas studied the severity psychometric characteristics of cognitions in patients with dementia due to vascular diseases of the brain, brain injury and epilepsy.Materials5 groups patients with dementia: F01.00 - 14 patients (mean age 55 years), F01.1 + F01.3 - 14 patients (mean age 60 years), F01.8 - 14 patients (mean age 65 years), F02.802 - 21 patients (mean age 50 years), F02.803 - 15 patients (mean age 38.5 years).MethodsThe psychometric methods: MMSE, FAB, Schulte, the clock drawing test, nonparametric statistical methods.Table of results:DiagnosisMMSEFABTable Schulte (seconds)Clock drawing testF02.80319,93±3,7313,30±2,1783,5±49,56,27±1,90F02.80220,04±4,1210,47±4,1597,5±536,66±2,18F01.0020,90±2,9810,27±3,37105±464,72±2,05F01.817,66±6,2010,11±3,33122±593,77±2,68F01.1+F01.317,40±6,538,30±3,33188±1175,12±1,45[Psychometric indicators of dementia]ConclusionSeverity of cognitive impairment is increasing in the following order:1)dementia due to epilepsy;2)dementia due to brain injury;3)acute post-stroke dementia;4)atherosclerotic, vascular dementia unspecified;5)multi-stroke, mixed cortical and subcortical vascular dementia.Disorders of frontal functions dominate in the structure of cognitive impairment in all dementias.