bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessment of Prevention of Mother-to-Child Transmission HIV Services in the Bantey Meanchey Province in Cambodia
Authors: Sau Mealiny Sokun , Balamane Maya , Lurie Mark , Harwell Joseph , Welle Emily , Mean Chhivun , Cu-Uvin Susan 
Published: September 2015

Background: Elimination of pediatric HIV requires a robust program for the prevention of mother-to-child transmission (PMTCT). The goal of this study was to assess the implementation of these services in Cambodia. Methods: This prospective study was conducted in Bantey Meanchey at 2 sites. Staff reviewed daily clinic and laboratory registration logs to gather data on PMTCT service access among antenatal women. Results: A total of 12 140 pregnant women received antenatal care. Only 4034 (33.2%) received pre-HIV test counseling. Of which 3407 (84.5%) received an HIV test. Eighteen (94.7%) of 19 women testing HIV-seropositive received triple-combination antiretroviral (ARV) medication. Fifteen HIV-exposed infants were delivered during the study. One infant tested HIV positive and is on ARV medication. Conclusion: Acceptance for HIV testing was high among women who received pretest counseling. An increase in the number of counselors may improve the rates of HIV testing. Follow-up mechanisms targeting mother–baby pairs should focus on increasing timely service uptake in the public sector.
Environmental exposure to pesticides and respiratory health
Authors: Mamane Ali , Raherison Chantal , Tessier Jean-François , Baldi Isabelle , Bouvier Ghislaine 
Published: September 2015

Respiratory effects of environmental exposure to pesticides are debated. Here we aimed to review epidemiological studies published up until 2013, using the PubMed database. 20 studies dealing with respiratory health and non-occupational pesticide exposure were identified, 14 carried out on children and six on adults.In four out of nine studies in children with biological measurements, mothers' dichlorodiphenyldichloroethylene (DDE) blood levels during pregnancy were associated with asthma and wheezing in young children. An association was also found between permethrin in indoor air during pregnancy and wheezing in children. A significant association between asthma and DDE measured in children's blood (aged 7–10 years) was observed in one study. However, in three studies, no association was found between asthma or respiratory infections in children and pesticide levels in breast milk and/or infant blood. Lastly, in three out of four studies where post-natal pesticide exposure of children was assessed by parental questionnaire an association with respiratory symptoms was found. Results of the fewer studies on pesticide environmental exposure and respiratory health of adults were much less conclusive: indeed, the associations observed were weak and often not significant.In conclusion, further studies are needed to confirm whether there is a respiratory risk associated with environmental exposure to pesticides.
Integration of interventional bronchoscopy in the management of lung cancer
Authors: Guibert Nicolas , Mazieres Julien , Marquette Charles-Hugo , Rouviere Damien , Didier Alain , Hermant Christophe 
Published: September 2015

Tracheal or bronchial proximal stenoses occur as complications in 20–30% of lung cancers, resulting in a dramatic alteration in quality of life and poor prognosis. Bronchoscopic management of these obstructions is based on what are known as “thermal” techniques for intraluminal stenosis and/or placement of tracheal or bronchial prostheses for extrinsic compressions, leading to rapid symptom palliation in the vast majority of patients. This invasive treatment should only be used in cases of symptomatic obstructions and in the presence of viable bronchial tree and downstream parenchyma.This review aims to clarify 1) the available methods for assessing the characteristics of stenoses before treatment, 2) the various techniques available including their preferred indications, outcomes and complications, and 3) the integration of interventional bronchoscopy in the multidisciplinary management of proximal bronchial cancers and its synergistic effects with the other specific treatments (surgery, radiotherapy or chemotherapy).
Early-life adversity and orbitofrontal and cerebellar volumes in
adults with obsessive–compulsive disorder: Voxel-based morphometry
study
Authors: Brooks Samantha J. , Naidoo Vanesh , Roos Annerine , Fouché Jean-Paul , Lochner Christine , Stein Dan J. 
Published: September 2015

BackgroundEarly-life adversity is a risk for obsessive–compulsive disorder (OCD),
but the impact at the neural level is less clear.AimsTo investigate the association between brain volumes and early-life
adversity in individuals with a diagnosis of OCD only.MethodThe Childhood Trauma Questionnaire (CTQ-28) was used to assess early-life
adversity in 21 participants with OCD and 25 matched healthy controls.
The relationship between global and regional brain volume and early-life
adversity was measured using voxel-based morphometry (VBM). All data were
corrected for multiple comparisons using family-wise error (FWE) at
P<0.05.ResultsIn the OCD group, correlations with total CTQ scores were positively
associated with a larger right orbitofrontal cortex volume. Physical
neglect was higher in the OCD group than in controls and was positively
associated with larger right cerebellum volume in the OCD group only.ConclusionsLarger brain volumes may reflect underlying developmental neuropathology
in adults with OCD who also have experience of childhood trauma.
Pre-milling Effects on Self-propagating Reactions in Mechanochemical Synthesis of CdSe and ZnSe
Authors: Ohtani Tsukio , Kusano Yoshihiro , Ishimaru Kenta , Morimoto Takato , Togano Akihiro , Yoshioka Teppei 
Published: September 2015

Abstract
CdSe was synthesized from an elemental mixture via a mechanically-induced self-propagating reaction (MSR). No reaction was observed in the induction period. When each elemental powder was separately pre-milled for 15 min, the elemental mixture formed CdSe after 5 s of milling, which is much shorter than that for MSR without the pre-milling process. It was thus deduced, that in the induction period, the mechanical energy supplied by the ball-milling process was employed primarily for activation of the particles. ZnSe was also formed via MSR from a pre-milled elemental mixture after 5 s of milling. The pre-milled Zn and Se powders showed lattice expansion, suggesting that the strain energy accumulated in the particles.
Acid-regulated Electron-transfer Disproportionation of a Nonsubstituted Tetramethyl-biacridine Derivative
Authors: Yamamoto Koji , Nakamura Toshikazu , Higashibayashi Shuhei 
Published: September 2015

Abstract
A 9,9,9′,9′-tetramethyl-4,4′,10,10′-biacridine derivative without substituents at 2,2′,7,7′-positions was synthesized. The X-ray analysis revealed formation of one-dimensional stacked column in the crystal. The compound underwent electron-transfer disproportionation by acid stimulus. The generated cation radical exhibited high stability in CH2Cl2 solution under air at room temperature over 10 days even without bulky protecting substituents. By neutralization with NEt3, biacridine was recovered in high yield via back electron transfer.
Intergeneric hybridisation between Berula erecta and Helosciadium nodiflorum (Apiaceae)
Authors: Desjardins Stuart D. , Leslie Alan C. , Stace Clive A. , Schwarzacher Trude , Bailey John P. 
Published: September 2015

AbstractA hybrid between Berula erecta and Helosciadium nodiflorum is reported from Chippenham Fen National Nature Reserve, Cambridgeshire, England. Parentage was investigated using chromosome counts, a maternally inherited chloroplast marker (rps16‐trnK), a biparentally inherited nuclear marker (ITS), and fluorescent in situ hybridisation (FISH) using labelled total genomic probes. Two parental genomes were identified in the putative hybrid (2n = 20), a maternal genome consisting of 9 chromosomes from B. erecta (2n = 18) and a paternal genome consisting of 11 chromosomes from H. nodiflorum (2n = 22). The implication of this hybrid for the taxonomy of the group is discussed, and a new hybrid genus is described: ×Beruladium (= Berula × Helosciadium). In overall appearance the hybrid resembles a small, creeping H. nodiflorum, and can be identified in the wild by a combination of characters: (1) the absence of a ring‐mark on the petiole below the lowest pair of leaflets that is characteristic of pure Berula, (2) lower leaves with up to five pairs of leaflets, (3) peduncles varying from shorter than to longer than rays, (4) umbels with several usually untoothed bracts, (5) a relatively long stigma and style, and (6) the absence of ripe fruits. The detection of this taxon is of considerable interest and, as far as we know, it is the first confirmed intergeneric hybrid in the Apiaceae within Europe.
Features of Modern Psycholinguistics Development and Communication in the Process of Teaching Foreign Languages and Cultures
Authors: Соколова  , Sokolova E. 
Published: September 2015

The article devoted to the particular features of psycholinguistics and communication
process in modern tendencies of teaching foreign languages
and cultures.
The author provides the basic problems of psycholinguistics and emphasizes
the role of language and consciousness in solving professional communication
problems.
Verbal Means of Speech Influence in Local Encyclopedic Text
Authors: Яковлев  , Yakovlev D. 
Published: September 2015

The article focuses on the analysis of verbal linguistic manipulation within
local encyclopaedic text relying on materials of local encyclopaedic texts
about Chelyabinsk.
The authors research considerable number of scientific works that use the
concept of verbal communication.
The major tasks are: defining the verbal communication concept, studying
main assets of speech influence, and analysing the bock of local encyclopaedic
texts to identify the means of persuasion and to form the list of
means of verbal influence within the local encyclopaedic text.
From the Experience of Training Russian As Foreign Language: Group and Individual Lessons for the Development of the Speech, with the Pupils, Having Different Level of Preparation
Authors: Салимова  , Salimova D. , Кудрявцева  , Kudryavtseva E. 
Published: September 2015

The article deals with the peculiarities of teaching Russian as a foreign language
by teachers of the department, the main burden of whom is to work
in the Russian groups, the preparation of teachers of Russian language and
literature. Special conditions, namely uneven preparedness for the group of
trainees, different goals and intentions of the students, a variety of ethnic
composition – all this requires from specialists in Russian philology maximum
compression and concentrated types and forms of learning, different
both in structure and content. Only the most advanced and complex methods
causing interest in the subject, participation in the classroom at the
same time two or three teachers, attraction to participate in the classroom
as a teaching and Russian students give the opportunity to work effectively
in a group of foreign nationals. Maximum results and maximum impact can
be achieved only by the individual form of training (two or three teachers
and one trainee).
Media Competence As a Part of Students’ Language Competence
Authors: Ковригина  , Kovrigina A. 
Published: September 2015

In this article we examine the notions of media competence and media critics,
which means a critical approach to mass media texts, from the point
of view of the needs of modern education not only for native speakers,
but also for students of foreign languages practicing with mass media material.
Special attention is paid to the question of students’ preparation to
real communication situations in Internet space. Strategies are proposed
for teachers to work with students in order to contribute to the development
of media competence.
Optimization of Industrial-Scale Assemble-to-Order Systems
Authors: van Jaarsveld Willem , Scheller-Wolf Alan 
Published: September 2015

Using a novel stochastic programming (SP) formulation, we develop an algorithm for inventory control in industrial-size assemble-to-order (ATO) systems that has unparalleled efficiency and scalability. Applying our algorithm to several numerical examples, we generate new insights regarding the control and optimization of these systems. We consider a continuous time model, seeking base-stock levels for components that minimize the sum of holding costs and product-specific backorder costs. Our initial focus is on first-come, first-served (FCFS) allocation of components to products; for this setting our algorithm quickly computes solutions for which the asymptotic optimality gap with the optimal FCFS base-stock policy is less than 1%. We then turn to two related questions: How do common heuristics used in practice compare to our performance, and how costly is the FCFS assumption? For the first question, we investigate the effectiveness of ignoring simultaneous stock-outs (ISS), a heuristic that has been used by companies such as IBM and Dell. Our experiments indicate that ISS performance, when compared to the optimal FCFS base-stock policy, improves as the average newsvendor (NV) fractiles increase but suffers under lead-time demand correlations. For the second question, we develop an efficiently computable upper bound on the benefit of optimal allocation over FCFS. We find that for many large ATO systems, FCFS performs surprisingly well and that its performance improves with decreasing NV fractile asymmetry among products and, again, with increasing average NV fractiles. We also investigate simple no-holdback allocation policies and find that they tend to outperform the best FCFS policies.
Becoming through a/r/tography, autobiography and stories in motion
Authors: LeBlanc Natalie , Davidson Sara Florence , Ryu Jee Yeon , Irwin Rita L. 
Published: September 2015

Abstract
The authors present stories in motion, reminding all those interested in practicebased research of the importance of a/r/tography as becoming-intensity, becoming-event and becoming-movement. Embracing a métissage approach, this article provides an example of art educators co-labouring in order to understand their need for materializing, theorizing and practising their ideas, and, in doing so, realize that being committed to emergence offers ways for becoming artist, researcher and teacher as ways of living one’s art practice as research.
Design students foreseeing the unforeseeable: Practicebased empathic research methods
Authors: McDonagh Deana 
Published: September 2015

Abstract
Designing for the future needs of people requires designers to develop an extensive research skill set and user-centred mindset. As our global community faces the unprecedented ageing tsunami, designers of tomorrow need to be prepared as effective design(er) researchers. Designers cannot rely upon a lengthy history of research methods to help shape our curricula, such as other more established disciplines, and this is both a challenge and an opportunity. As we prepare our students for positions and jobs that may not yet exist, we also have to prepare them for professional expectations that are still emerging. This article discusses a number of practice-based research methods and tools that are helping to contribute to the design student’s skill set whilst also shaping their mindset in terms of ageing, disability and emotional needs of users. In addition, practice-based research is shaping the way we teach, learn and connect with others beyond the classroom.
BRAF V600E and decreased NIS and TPO expression are associated with aggressiveness of a subgroup of papillary thyroid microcarcinoma
Authors: Bastos André Uchimura , Oler Gisele , Nozima Bruno Heidi Nakano , Moysés Raquel Ajub , Cerutti Janete Maria 
Published: September 2015

BackgroundThyroid cancer incidence has dramatically increased worldwide over the last two decades. The rise is mostly due to an increased detection of small papillary thyroid carcinomas (PTCs) (≤20 mm), predominantly microPTC (≤10 mm). Although small tumors generally have an excellent outcome, a considerable percentage may have a more aggressive disease and worse prognosis. The clinical challenge is to preoperatively identify those tumors that are more likely to recur.AimTo improve risk stratification and patient management, we sought to determine the prognostic value of BRAF V600E,NRASorRET/PTCmutations in patients with PTC measuring <20 mm, mainly microPTC.MethodsThe prevalence ofRET/PTCfusion genes was examined by quantitative RT-PCR. BRAF V600E and NRAS Q61 mutations were determined by PCR sequencing. To further elucidate why some small PTC are less responsive to radioactive iodine treatment therapy, we explored if these genetic alterations may modulate the expression of iodine metabolism genes (NIS,TPO,TG,TSHRandPDS) and correlated with clinico-pathological findings that are predictors of recurrence.ResultsThis study shows that tumors measuring ≤20 mm exhibited higher prevalence of BRAF V600E mutation, which correlated with aggressive histopathological parameters, higher risk of recurrence, and lower expression ofNISandTPO. Although this correlation was not found when microPTC were evaluated, we show that tumors measuring 7–10 mm, which were positive for BRAF mutation, presented more aggressive features and lower expression ofNISandTPO.ConclusionWe believe that our findings will help to decide the realistic usefulness of BRAF V600E mutation as a preoperative marker of poor prognosis in small PTC, primarily in microPTC.
Turbulent burning velocity in combustion chamber of SI engine fueled with compressed biogas
Authors: Ga Bui Van , Dong Nguyen Van , Hung Bui Van 
Published: September 2015

Turbulent burning velocity is the most important parameter in analyzing pre-mixed combustion simulation of spark ignition engines. It depends on the laminar burning velocity and turbulence intensity in the combustion chamber. The first term can be predicted if one knows fuel composition, physico chemical properties of the fluid. The second term strongly depends on the geometry of the combustion chamber and fluid movement during the combustion process. One cannot suggest a general expression for different cases of engine. Thus, for accuracy modeling, one should determine turbulent burning velocity in the combustion chamber of each case of engine individually. In this study, the turbulent burning velocity is defined by a linear function of laminar burning velocity in which the proportional constant is defined as the turbulent burning velocity coefficient. This coefficient was obtained by analyzing the numerical simulation results and experimental data and this is applied to a concrete case of a Honda Wave motorcycle engine combustion chamber that fueled with compressed biogas. The results showed that the turbulent burning velocity coefficient in this case is around 1.3 when the average engine revolutions is in the range of 3000 rpm to 6000 rpm with biogas containing 80% Methane. We can then predict the effects of different parameters on the performance of the engine fueled with compressed biogas by simulation.
An analysis of the economic impact of drug-coated balloon use for the treatment of peripheral artery disease
Authors: Micari Antonio , Vadalà Giuseppe , Corbo Mara , D'Alessandro Gianluigi , Castriota Fausto , Cremonesi Alberto 
Published: September 2015

<p><strong>Background</strong>: Drug-coated balloons (DCBs) are an alternative for patients with peripheral arterial disease. Costs and re-intervention rates are potentially reduced compared to other technologies. We assessed the economic impact of these endovascular therapies.</p><p><strong>Methods</strong>: An Italian National Healthcare Service-perspective budget impact model with a 5-year horizon was developed to compare relative costs of 4 index procedures (plain old balloon angioplasty (POBA), DCBs, and bare-metal and drug-eluting stents (BMSs, DESs)) based on 1-year repeat-procedure rates (target-lesion revascularization (TLR)). A published systematic review of TLR rates in patients with femoral-popliteal disease undergoing these treatments was used to measure effectiveness. Costs associated with each treatment were derived from diagnosis-related group tariffs. A decision analytic model was developed to estimate 1-year costs for index procedures and possible revascularizations.</p><p> </p><p><strong>Results</strong>: Pooled TLR rates show clear patient benefits for DCBs (6.9%) compared with POBA (21.6%) and BMSs (14.2%) and non-inferiority vs. DESs (7.3%). One-year payments for index and repeat interventions (by TLR rate) showed that DCBs were the least costly strategy, saving ~€1,000/patient vs. POBA. The potential savings were €8.7M, assuming 5% annual increase in DCB adoption over 5 years. <strong></strong></p><p><strong>Conclusions</strong>: Despite initial higher investment, DCB represent a cost-saving alternative to other technologies. <strong></strong></p>
The Effect of Employee Treatment Policies on Internal Control Weaknesses and Financial Restatements
Authors: Guo Jun , Huang Pinghsun , Zhang Yan , Zhou Nan 
Published: September 2015

ABSTRACT
This study investigates the role of employment policies in reducing internal control ineffectiveness and financial restatements. We provide new evidence that employee treatment policies are an important predictor of ineffective internal control. We also find that employee-friendly policies significantly reduce the propensity for employee-related material weaknesses. These results suggest that greater employee benefits facilitate the acquisition, development, and motivation of the workforce and ameliorate the loss of valuable human capital, thereby mitigating employee failures to implement internal control tasks properly. Moreover, we document novel results that financial restatements, especially those caused by unintentional errors, are less likely to arise in firms that invest more in employee benefits. Collectively, our emphasis on the effect of employee treatment policies on the integrity of internal control and financial reporting distinguishes our paper from previous studies that focus on the role of top executives in accounting practices.
Data Availability: Data are available from public sources indicated in the text.
The Economic Consequences of Tax Service Provider Sanctions: Evidence from KPMG's Deferred Prosecution Agreement
Authors: Finley Andrew R. , Stekelberg James 
Published: September 2015

ABSTRACT
This study investigates the effect of KPMG's Deferred Prosecution Agreement (DPA) on the accounting firm's ability to sell auditor-provided tax services (APTS) and its clients' tax avoidance. We document that following the DPA, clients were more likely to discontinue or reduce purchasing APTS from KPMG relative to the other Big 4 accounting firms. However, we do not find any evidence of a change in tax avoidance among KPMG clients continuing to purchase APTS following the DPA relative to other Big 4 clients. Broadly, our findings highlight how elevated reporting standards and external monitoring impose significant negative economic consequences on the service providers subject to these sanctions. At the same time, it appears clients do not suffer any observable tax costs by continuing to engage a sanctioned tax service provider.