bluuebunny/crossref_metadata_2025_split huggingface dataset:
Influence of Initial pH Values on the Lag Phase of Escherichia coli and Bacillus licheniformis Batch Cultures
Authors: Palmen Thomas G. , Scheidle Marco , Huber Robert , Kamerke Claudia , Wilming Anja , Dittrich Barbara , Klee Doris , Büchs Jochen 
Published: April 2013

AbstractRobust and reproducible processes are necessary to achieve a constant and high quality of biotechnological products. Thus, suitable online measurement systems and an increased understanding of the parameters influencing the process are required. In this study, two online measurement devices were used to detect the influence of the initial pH value on the lag phase of three E. coli and one B. licheniformis strains cultivated in buffered mineral media. It was shown that the initial pH value, the type of buffer and its concentration have to be carefully chosen to avoid differences in the lag phase, unsuitable pH values during the cultivation, and osmotically inhibiting high buffer concentrations.
Autologous retransplantation for patients with recurrent multiple myeloma
Authors: Sellner Leopold , Heiss Christiane , Benner Axel , Raab Marc S. , Hillengass Jens , Hose Dirk , Lehners Nicola , Egerer Gerlinde , Ho Anthony D. , Goldschmidt Hartmut , Neben Kai 
Published: April 2013

BACKGROUNDTherapeutic options for patients with recurrent multiple myeloma after autologous stem cell transplantation (ASCT) include novel agents, conventional chemotherapy, or salvage ASCT with no standard of care.METHODSA total of 200 patients with multiple myeloma who developed disease recurrence after treatment with upfront ASCT and received an autologous retransplantation as salvage therapy at the study center over a period of 15 years were retrospectively reviewed. The objective of the current study was to evaluate the role of salvage ASCT in terms of efficacy, particularly taking into account the impact of novel agents.RESULTSThe median progression‐free survival (PFS) and overall survival after salvage ASCT were 15.2 months and 42.3 months, respectively. The overall response rate (a partial response or greater) was 80.4% at day 100, excluding 6 patients who died before assessment. Factors associated with improved PFS and overall survival after salvage ASCT included an initial PFS of > 18 months after upfront ASCT, bortezomib‐containing or lenalidomide‐containing therapies for reinduction, response to reinduction, and an International Staging System stage of I before salvage ASCT.CONCLUSIONSSalvage ASCT is capable of achieving sustained disease control in patients with multiple myeloma. The use of lenalidomide and bortezomib for reinduction has improved the results after salvage ASCT, suggesting that novel agents and salvage ASCT are complementary rather than alternative treatment approaches. Cancer 2013;119:2438‐2446. © 2013 American Cancer Society.
A family of memristor‐based reactance‐less oscillators
Authors: Zidan Mohammed Affan , Omran Hesham , Smith Casey , Syed Ahad , Radwan Ahmed Gomaa , Salama Khaled Nabil 
Published: April 2013

SUMMARYIn this paper, we present for the first time a family of memristor‐based reactance‐less oscillators (MRLOs). The proposed oscillators require no reactive components, that is, inductors or capacitors, rather, the ‘resistance storage’ property of memristor is exploited to generate the oscillation. Different types of MRLO family are presented, and for each type, closed form expressions are derived for the oscillation condition, oscillation frequency, and range of oscillation. Derived equations are further verified using transient circuit simulations. A comparison between different MRLO types is also discussed. In addition, detailed fabrication steps of a memristor device and experimental results for the first MRLO physical realization are presented. Copyright © 2013 John Wiley & Sons, Ltd.
An in situ approach to detect tree root ecology: linking ground‐penetrating radar imaging to isotope‐derived water acquisition zones
Authors: Isaac Marney E. , Anglaaere Luke C. N. 
Published: April 2013

AbstractTree root distribution and activity are determinants of belowground competition. However, studying root response to environmental and management conditions remains logistically challenging. Methodologically, nondestructive in situ tree root ecology analysis has lagged. In this study, we tested a nondestructive approach to determine tree coarse root architecture and function of a perennial tree crop, Theobroma cacao L., at two edaphically contrasting sites (sandstone and phyllite–granite derived soils) in Ghana, West Africa. We detected coarse root vertical distribution using ground‐penetrating radar and root activity via soil water acquisition using isotopic matching of δ18O plant and soil signatures. Coarse roots were detected to a depth of 50 cm, however, intraspecifc coarse root vertical distribution was modified by edaphic conditions. Soil δ18O isotopic signature declined with depth, providing conditions for plant–soil δ18O isotopic matching. This pattern held only under sandstone conditions where water acquisition zones were identifiably narrow in the 10–20 cm depth but broader under phyllite–granite conditions, presumably due to resource patchiness. Detected coarse root count by depth and measured fine root density were strongly correlated as were detected coarse root count and identified water acquisition zones, thus validating root detection capability of ground‐penetrating radar, but exclusively on sandstone soils. This approach was able to characterize trends between intraspecific root architecture and edaphic‐dependent resource availability, however, limited by site conditions. This study successfully demonstrates a new approach for in situ root studies that moves beyond invasive point sampling to nondestructive detection of root architecture and function. We discuss the transfer of such an approach to answer root ecology questions in various tree‐based landscapes.
Layer‐by‐layer assembly of photonic crystal using DNA
Authors: Kimura Yoshinori , Kaneda Shohei , Fujii Teruo , Murata Satoshi 
Published: April 2013

AbstractPhotonic crystals are a key component for optical next‐generation communication and computing in that they have a periodic 3D structure on the same scale as optical wavelengths. The major diﬃculty in the practical use of photonic crystals exists in its fabrication process. As an optical component, it must be a defect‐free large crystal with waveguide patterns aﬀecting the propagation of photons. Many attempts have been made to realize such a crystal, but low‐cost and rapid fabrication of a defect‐free large crystal is still a diﬃcult problem. Here, we propose a novel fabrication method combining colloidal crystallization and DNA nanotechnology. In this method, a face‐centered lattice made of 1‐µm polystyrene particles is assembled on a patterned template in a layer‐by‐layer fashion. In order to control the binding among particles, DNA‐gold nano‐particle conjugates (10‐nm GNP modiﬁed with 52mer DNA) are used. Speciﬁc bonding rules between particles and GNPs deﬁned by the base sequence of DNA results in the layer‐by‐layer growth of the crystal. We have built two‐layer crystals using the proposed method, and the results show its feasibility. We also found some important factors necessary to improve the quality of the crystal. © 2013 Wiley Periodicals, Inc. Electron Comm Jpn, 96(5): 42–49, 2013; Published online in Wiley Online Library (wileyonlinelibrary.com). DOI 10.1002/ecj.11377
Dynamic quantizer design for MIMO systems based on communication rate constraint
Authors: Okajima Hiroshi , Sawada Kenji , Matsunaga Nobutomo , Minami Yuki 
Published: April 2013

AbstractThis paper proposes a design method for dynamic quantizers in a MIMO networked control system. It is well known that feedback‐type dynamic quantizers are eﬀective for the quantization of data series in the sense of noise shaping. The dynamic quantizers include a set of a dynamic ﬁlter and a static quantizer. When it is required to use the quantizer in network communication, the data size of the signal should be minimized appropriately by the quantizers. We have proposed a design method for dynamic quantizers in a SISO system based on the communication rate constraint. In this paper, the design method is extended to MIMO systems. Using this extension, the communication rate constraint for one type of concentrated system can be handled. In the setting of the quantizer for a MIMO system, bit assignment is an important matter for the appropriate design of information ﬂow. The eﬀectiveness of the proposed design method is shown using numerical examples. © 2013 Wiley Periodicals, Inc. Electron Comm Jpn, 96(5): 28–36, 2013; Published online in Wiley Online Library (wileyonlinelibrary.com). DOI 10.1002/ecj.11396
Mega‐solar optimal allocation using data envelopment analysis
Authors: Yokota Shinya , Kumano Teruhisa 
Published: April 2013

AbstractIn this paper, the optimal allocation of mega‐solar is examined using data envelopment analysis (DEA). A great deal of attention is paid to photovoltaic power generation in Japan. Because such power generation can be freely used, it is attractive in Japan, which has few natural resources. The allocation of mega‐solar, a large‐scale photovoltaic power generation method, is an important problem for meeting the hope of eﬃcient operation. We tried to apply DEA in Shizuoka Prefecture and to solve this issue. In this type of DEA application, some analyses often result in zero weighting factors in the parameters of some items to be studied, which implies that the corresponding items are not appropriately evaluated. The existing studies do not give special consideration to this situation. In this study, a new calculation scheme is proposed, the above‐stated problems are successfully resolved, and the optimal candidate sites have been selected for the mega‐solar allocation. © 2013 Wiley Periodicals, Inc. Electr Eng Jpn, 183(4): 24–32, 2013; Published online in Wiley Online Library (wileyonlinelibrary.com). DOI 10.1002/eej.22322
Reduction and Hydrogenation of a Diazene by a (β‐Diketiminato)nickel Hydrazide
Authors: Köthe Claudia , Metzinger Ramona , Limberg Christian 
Published: April 2013

AbstractA (β‐diketiminato)nickel(II) hydrazido(1–) complex [LtBuNi(η2‐N2H3)], {1, LtBu = [HC(CtBuNC6H3{iPr}2)2]–} has been obtained by treatment of [LtBuNiBr] with hydrazine. In a reaction of 1 with two equivalents of the azo compound diisopropyl azodicarboxylic ester (adc–OiPr) the Ni(N2H3) entity acts as both a hydrogenating and a reducing agent: diisopropyl hydrazidodicarboxylate (hdc–OiPr) is formed, and more adc–OiPr is reduced by two electrons. The resulting (adc–OiPr)2– is found as a ligand in the ultimate nickel product complex, the trinuclear nickel(II) compound [LtBuNi(μ‐adc–OiPr)Ni(μ‐adc–OiPr)NiLtBu] (2), in which two LtBuNi+ units are linked by a [NiII(adc–OiPr)2]2– moiety. The hypothesis that LtBuNiI species are acting as intermediates was supported by the independent finding that 2 can also be obtained by reaction of [LtBuNi(OEt2)] with adc–OiPr.
Molecular Heterobimetallic Aluminoxanes and Aluminoxane Sulfides Containing Group 4 Metals
Authors: Hidalgo‐Bonilla Sandra , Peyrot Ricardo , Jancik Vojtech , Barroso‐Flores Joaquín , Reyes‐Lezama Marisol , Moya‐Cabrera Mónica 
Published: April 2013

AbstractReactivity studies of aluminoxane hydroxide and hydrogensulfide [{MeLAl(EH)}2(μ‐O)] {MeL = CH[CMe(NAr)]2– (Ar = 2,4,6‐Me3C6H2); E = O (1), S (2)} with Group 4 amides led to the molecular heterobimetallic aluminoxanes [(MeLAlO)2(μ‐O){M(NR2)2}] [M = Ti, R = Me (3); M = Zr, R = Me (4), Et (5); M = Hf, R = Me (6), Et (7)] and aluminoxane sulfides [(MeLAlS)2(μ‐O){M(NR2)2}] [M = Ti, R = Me (8), Et (9); M = Zr, R = Me (10), Et (11); M = Hf, R = Me (12), Et (13)], respectively. The structural analyses of these compounds reveal six‐membered inorganic cores that exhibit Al–E–M (E = O, S; M = Ti, Zr, Hf) moieties. Compounds 10–13 exhibit strong O···M (M = Zr, Hf) transannular bonding, whereas 8 and 9 exhibit relatively short Ti–S bond lengths. DFT calculations performed on 8–13 at the B3LYP/LANL2DZ level of theory indicate that the titanium atoms in 8 and 9, despite having the lowest transannular bond index, have the highest total Wiberg bond indexes. This can be rationalized in terms of the high Ti–S bond indexes, which indicate an important degree of electron density delocalized from the sulfur atoms to the titanium atom.
Chlorosilanes and 3,5‐Dimethylpyrazole: Multinuclear Complexes, Acetonitrile Insertion and 29Si NMR Chemical‐Shift Anisotropy Studies
Authors: Bitto Florian , Kraushaar Konstantin , Böhme Uwe , Brendler Erica , Wagler Jörg , Kroke Edwin 
Published: April 2013

AbstractThe multinuclear silicon complexes [{H2ClSi(μ‐pz*)2}2SiH2] (1) and [Cl2Si(μ‐pzRR)2SiCl2] (2, R = Me; 3, R = Ph) were formed by the reaction of dichlorosilane (for 1) or hexachlorodisilane with 1‐trimethylsilyl‐3,5‐dimethylpyrazole (for 1 and 2) and the 3,5‐diphenyl analogue (for 3). The reaction of trichlorosilane with 3,5‐dimethylpyrazole (Hpz*) in MeCN resulted in the formation of two MeCN insertion products of 2 (4, 5). From different samples of synthesis products of this work a preferred hydrolysis product was obtained: [{(μ‐pz*)2SiH}3–μ3‐O]+Cl– (6). The structural and electronic features of the compounds synthesised in this work were analysed with single‐crystal X‐ray diffraction and 29Si cross‐polarisation (CP)/magic‐angle spinning (MAS) NMR spectroscopy combined with quantum chemical computations to investigate their 29Si chemical‐shift anisotropy principal tensor components.
Understanding the limits of self‐control: Positive affect moderates the impact of task switching on consecutive self‐control performance
Authors: Wenzel Mario , Conner Tamlin S. , Kubiak Thomas 
Published: April 2013

AbstractPerforming consecutive self‐control tasks typically leads to deterioration in self‐control performance. This effect can be explained within the strength model of self‐control or within a cognitive control perspective. Both theoretical frameworks differ in their predictions with regard to the impact of affect and task characteristics on self‐control deterioration within a two‐task paradigm. Whereas the strength model predicts decrements in self‐control performance whenever both tasks require a limited resource, under a cognitive control perspective, decrements should only occur when people switch to a different response conflict in the second task. Moreover, only the cognitive control model predicts an interaction between task switching and positive affect. In the present research, we investigated this interaction within a two‐task paradigm and found evidence that favored a cognitive control interpretation of the results. Positive affect only benefitted consecutive self‐control performance if response conflicts in the two tasks were different (resisting sweets followed by a Stroop task). If they were the same (two consecutive Stroop tasks), positive affect impaired self‐control performance. These effects were partially replicated in the second study that also examined negative affect, which did not affect self‐control performance. We conclude that drawing on cognitive control models could add substantially to research on self‐control. Copyright © 2013 John Wiley & Sons, Ltd.
When relationships do not live up to benevolent ideals: Women's benevolent sexism and sensitivity to relationship problems
Authors: Hammond Matthew D. , Overall Nickola C. 
Published: April 2013

AbstractBenevolent sexism promises women a revered place within intimate relationships, which should lead to greater dissatisfaction when they face relationship difficulties. We collected self‐reports of relationship problems and relationship satisfaction (Study 1; N = 91 heterosexual couples), relationship problems and relationship evaluations daily over 3 weeks (Study 1), and hurtful partner behaviour and relationship evaluations over 10 days (Study 2; N = 86 women). Women's endorsement of benevolent sexism predicted sharper declines in relationship satisfaction when they faced greater relationship problems (Study 1) and hurtful partner behaviour (Study 2). These effects were magnified in longer relationships (Studies 1 and 2), indicating that the sensitivity to relationship problems associated with women's endorsement of benevolent sexism is particularly pronounced when women have more invested in their relationship role being revered and cherished. The results suggest that women who endorse benevolent sexism are vulnerable within their relationships because their satisfaction is contingent upon the fulfilment of the promises of benevolent sexism. Copyright © 2013 John Wiley & Sons, Ltd.
There's no “I” in team: Effects of cooperative video games on cooperative behavior
Authors: Greitemeyer Tobias , Cox Christopher 
Published: April 2013

AbstractThe present research tests the idea that playing a team‐player video game in which players work together as teammates and assist each other in achieving a common goal increases cooperative behavior toward a new partner. In fact, relative to a single‐player mode, cooperatively playing a video game increased cooperation in a mixed‐motive decision dilemma task. Because the players were exposed to the same video game content in both experimental conditions, the effect on cooperative behavior can only be accounted for by the different way the game was played. Mediation analyses revealed that cooperative team play promoted feelings of cohesion, which activated trust (i.e., the expectation of reciprocal cooperation), which in turn increased cooperative behavior. Copyright © 2013 John Wiley & Sons, Ltd.
A novel group access authentication and key agreement protocol for machine‐type communication
Authors: Lai Chengzhe , Li Hui , Li Xiaoqing , Cao Jin 
Published: April 2013

AbstractMachine‐to‐machine communications have been actively engaged in by the standardisation and industry areas, also defined as machine‐type communication (MTC) in the release 10 of the 3rd Generation Partnership Project. The scenarios of 3rd Generation Partnership Project have been regarded as the promising solution facilitating machine‐to‐machine communications, which is being standardised as an emphatic application to be supported by long‐term evolution advanced. In this paper, we propose a novel group access authentication and key agreement protocol for MTC devices, which effectively reduces authentication costs compared with conventional schemes. In our proposed protocol, the first MTC device accessing the network performs a full authentication and key agreement authentication procedure and obtains a group temporary key and group authentication information on behalf of other MTC devices in the same group; then, the remaining MTC devices perform a simplified authentication procedure locally. The key derivation and group member joining and leaving are also discussed. Finally, the security of the proposed protocol is verified by using the AVISPA toolkit, and extensive evaluations of performance illustrate that the proposed protocol achieves better performance in terms of the bandwidth consumption, the number of signaling messages between the home network and the serving network, the computation cost and the storage cost in the serving network compared with several existing schemes. Copyright © 2013 John Wiley & Sons, Ltd.
Aragonite saturation state dynamics in a coastal upwelling zone
Authors: Harris Katherine E. , DeGrandpre Michael D. , Hales Burke 
Published: April 2013

AbstractCoastal upwelling zones may be at enhanced risk from ocean acidification as upwelling brings low aragonite saturation state (ΩAr) waters to the surface that are further suppressed by anthropogenic CO2. ΩAr was calculated with pH, pCO2, and salinity‐derived alkalinity time series data from autonomous pH and pCO2 instruments moored on the Oregon shelf and shelf break during different seasons from 2007 to 2011. Surface ΩAr values ranged between 0.66 ± 0.04 and 3.9 ± 0.04 compared to an estimated pre‐industrial range of 1.0 ± 0.1 to 4.7 ± 0.1. Upwelling of high‐CO2 water and subsequent removal of CO2 by phytoplankton imparts a dynamic range to ΩAr from ~1.0 to ~4.0 between spring and autumn. Freshwater input also suppresses saturation states during the spring. Winter ΩAr is less variable than during other seasons and is controlled primarily by mixing of the water column.
Unexpected Reaction Course of 3‐Amino‐5‐aryl‐1H‐pyrazoles with Dialkyl Dicyanofumarates
Authors: Ali Korany A. , Ragab Eman A. , Mlostoń Grzegorz , Celeda Małgorzata , Linden Anthony , Heimgartner Heinz 
Published: April 2013

AbstractOn treatment of 3‐amino‐5‐aryl‐1H‐pyrazoles 1 with dialkyl dicyanofumarates (=(E)‐but‐2‐enedioates) 4 in boiling 1,2‐dichloroethane, two competitive reactions occurred leading to 3‐aryl‐5‐cyano‐6,7‐dihydro‐6‐oxo‐1H‐pyrazolo[3,4‐b]pyridine‐4‐carboxylates 10 and 7‐amino‐2‐arylpyrazolo[1,5‐a]pyrimidine‐5,6‐dicarboxylates 11. In DMF at room temperature, as well as at 100°, only compounds 10 were isolated. The formation of the major products of type 10 was rationalized via Michael addition of 1 as a C(4)‐nucleophile onto 4, followed by HCN elimination and lactamization. On the other hand, the minor products 11 result from a Michael addition of 1 onto 4 via the NH2 group, and subsequent HCN elimination and cyclization. The structures of the products have been established by X‐ray crystallography.
Emerging roles of endoglin/CD105 and angiogenic cytokines for disease development and progression in multiple myeloma patients
Authors: Pappa CA , Alexandrakis MG , Boula A , Psarakis FE , Kolovou A , Bantouna V , Stavroulaki E , Tsirakis G 
Published: April 2013

AbstractAngiogenesis is an essential process for the expansion of multiple myeloma (MM), in which many angiogenic factors participate. Endoglin (CD105) is a transforming growth factor‐β co‐receptor, being mainly expressed in angiogenic endothelial cells and has been used as a marker of tumor angiogenesis, having prognostic potential. The aim of the study was to evaluate serum levels of soluble CD105 (sCD105) in MM patients, both during diagnosis and after effective conventional chemotherapy, in the plateau phase, and to correlate them with the clinical stage of the disease, as well as with the known angiogenic factors vascular endothelial growth factor, angiogenin and interleukin‐18 (IL‐18). Serum levels of the aforementioned factors were measured, by enzyme‐linked immunosorbent assay, in 56 newly diagnosed MM patients, in 35 of them who entered plateau phase and in 24 healthy controls. Bone marrow aspirations were also performed in all patients to determine plasma cell infiltration. All measured cytokines were higher in MM patients compared with controls and with advancing disease stage (p < 0.001 for all cases). Furthermore, the values of all factors decreased significantly in the plateau phase (p < 0.001 for all cases). Serum levels of sCD105 correlated with the other angiogenic cytokines, whereas only serum levels of angiogenin had prognostic value for the survival. In conclusion, CD105 and the angiogenic cytokines vascular endothelial growth factor, angiogenin and IL‐18, seem to have emerging roles both in angiogenesis and tumor growth in MM. Copyright © 2013 John Wiley & Sons, Ltd.