bluuebunny/crossref_metadata_2025_split huggingface dataset:
Methodical Approach to Determine the Influence of Economic Activity in the Region on the State of the Territorial Environment of the Territory
Authors: Berezina Olena , Petrovskiy Maksim 
Published: January 2015

Abstract
The goal of this research work is the formation of methodological approach of ecological factor assessment impact on the development level of territorial economic systems. This article presents the quality indicators of the development of socio-economic areas, which reflect total level and the extent of human impact on the natural environment characterizing the level of economy influence (economic activities) on the environment. This article suggests the approach to the calculation of Eco-intensity indicator and general air pollution dynamics in Ukraine, regarding regions, type of economic activities/industries. The research studies the comparative evaluation and the characteristics of the ecological status of the territories. It was determined that for the period from 2005 till 2012 the emissions of pollutants into the atmosphere from stationary and mobile pollution sources are being gradually reduced due to the decreasing level of production enterprises, which were the main polluters of the atmosphere. According to the types of economic activity, the measurements of Eco-intensity emissions of pollutants and carbon dioxide indicated that the biggest indices were in energy distribution, mining and processing industries.
Species Complexes of Predatory Phytoseiid Mites (Parasitiformes, Phytoseiidae) in Green Urban Plantations of Uman’ (Ukraine)
Authors: Grabovska S. L , Kolodochka L. A 
Published: January 2015

Abstract
Structure of species complexes of predatory phytoseiid mites (Phytoseiidae) and their distribution were studied in plant associations of Uman’ town (Cherkasy Region, Ukraine). Twelve species of seven genera of phytoseiid mites were revealed. It was observed centripetal reduction of the species diversity in the phytoseiid complexes from the outlying districts to the center of the town.
Comparative Analysis of Karyotypes of Two Cryptic Species of Pelobatid Frogs (Amphibia, Anura) of Ukraine
Authors: Suryadnaya N. N 
Published: January 2015

Abstract
The paper first describes in detail the karyotype of Pelobates vespertinus (Pallas, 1771) in comparison with the karyotype of Pelobates fuscus (Laurenti, 1768). Comparative morphological analysis of chromosomes has shown that these two cryptic species have a symmetrical karyotype consisting of two-armed chromosomes. It has been established that their chromosome sets consist of 7 pairs of large chromosomes and 6 pairs of small ones. The species diff er by the position of the centromere in the chromosomes of the 10th and 11th pairs. The 10th pair of P. fuscus is metacentrics, the 11th pair is submetacentric; the 10th pair of P. vespertinus is submetacentric, and the 11th one is metacentrics. Secondary constrictions are on the short arms of the 7th chromosome pair. The chromosomal formula for both species is 4 meta-(m) + 7 submeta-(sm) + 2 subtelocentrics (st), 2n = 26, N.F. = 52. Absolute length of all the chromosomes in the karyotype of P. fuscus is somewhat larger than that one in the karyotype of P. vespertinus. The parameters of relative length are equivalent on average, but they diff er in individual chromosomes. On the background of established chromosomal differences between the cryptic species, reliable diagnostic features have not been identified.
Unusual Age Structure of the Winter Aggregation of Nyctalus Noctula (Mammalia, Chiroptera) in Kyiv
Authors: Godlevska L. V , Gol’din P. E 
Published: January 2015

AbstractWe analysed the sex and age composition of a large colony of Nyctalus noctula (605 specimens), wintering in Kyiv, Ukraine. Age was identified in 113 individuals using the method of counting growth layer groups in dentine. Males contained ca. 70 % both in the colony and in the sample of animals with the estimated ages. Males and females of all ages were in good body condition. There were bats from 0+ to 7+ years old in the sample. In males, 0+ age class was represented by 38 %; 1+ class, by 20 % of individuals. In females, 0+ and 1+ year old individuals were found in similar numbers: 29 % and 32 % correspondingly. The observed sex ratio and proportions of males and females across age classes cannot be explained only by demography. The data are interpreted in terms of migratory behaviour and mating strategy of the species: the unusual female age structure is possibly due to age-specific preferences in wintering habitat selection and search for potential mating partners.
A Survey of Gill Histopathology of Thirteen Common Fish Species in the Sanyati Basin, Lake Kariba, Zimbabwe/ Badania Histopatologiczne Skrzeli Trzynastu Pospolitych Gatunków Ryb W Zlewni Sanyati, Jezioro Kariba, Zimbabwe
Authors: Mabika Nyasha , Barson Maxwell 
Published: January 2015

Abstract
Following a study of gill pathology in African catfish (Clarias gariepinus) and Nile Tilapia (Oreochromis niloticus) from the Sanyati Basin of Lake Kariba, Zimbabwe, a similar survey was carried out in thirteen other common fishes of Lake Kariba. Gill tissues were dissected from the fish, preserved and prepared for histology. The prepared tissue sections were observed under a light microscope. Six histopathological lesions were observed, namely epithelial lifting, hyperplasia, lamellae fusion, parasitic cysts, oedema, and aneurysm. Epithelial lifting was prevalent in all fish species whilst aneurysm was only observed in two fish species. Synodontis zambezensis had the highest prevalence of gill lesions whilst Marcusenius microlepidotus, Brycinus imberi and Micralestes acutidens had the least prevalence of lesions. Most of these histopathological lesions were mild to moderate, and this is suggestive of good health of the fish species investigated. Seventy seven percent of the fish species were infected with monogenean ectoparasites. More research on fish health in Lake Kariba is recommended and future studies should aim to quantify these histological changes in relation to environmental conditions of the lake. This will enable histopathology to be used as a biomarker or predictor of water quality.
Dorsal Surface of the Tongue of the Hazel Dormouse Muscardinus Avellanarius: Scanning Electron and Light Microscopic Studies/ Grzbietowa Powierzchnia Języka Orzesznicy Muscardinus Avellanarius: Badania Z Wykorzystaniem Mikroskopu Skaningowego I Świetlnego
Authors: Wołczuk Katarzyna 
Published: January 2015

Abstract
The dorsal surface of a hazel dormouse tongue was examined by scanning electron and light microscopy. The tongue of the hazel dormouse is elongated and widened in the proximal part. On the proximal one-third of the tongue a clear median groove is observed. The dorsal lingual surface was covered with five types of papillae: filiform, conical, fungiform, vallate and foliate. The arrangement, shape, size and direction of the filiform papillae vary depending on the region of the tongue. On the proximal part of the tongue, the filiform papillae are saw-like and tilted medioposteriorly, while on the distal part they have a fork-like shape and form a radial pattern with their processes oriented towards the center of the tongue. Fungiform papillae with single taste buds are evenly scattered on the anterior and middle part of the tongue body. On the root of the tongue, three star-like shaped vallate papillae are arranged in the form of a triangle and surrounded by conical papillae. A pair of foliate papillae are found on both edges of the posterior area of the tongue, forming three parallel folds separated by deep grooves. The dorsal surfaces of the vallate and foliate papillae are covered with hard-cornified epithelium, while the lateral surfaces have noncornified epithelium with numerous taste buds. The results of our studies show that the tongue structure of the hazel dormouse is more primitive in comparison with other rodents which is related to their phylogeny and feeding habits.
Endoscopic Dacryocystorhinostomy with Silicone, Polypropylene, and T-tube Stents; Randomized Controlled Trial of Efficacy and Safety
Authors: Okuyucu Semsettin , Gorur Hatice , Oksuz Huseyin , Akoglu Ertap 
Published: January 2015

Objective To compare the efficacy and safety of endoscopic dacryocystorhinostomy (En-DCR) with different stent materials for lacrimal sac intubation in primary nasolacrimal ductal obstructions. Study Design Randomized controlled study with three parallel groups. Level of evidence is 1b. Methods A total of 91 patients (five bilateral) with primary nasolacrimal duct obstruction (NLDO) at a tertiary referral center scheduled for En-DCR were to allocated into three stent groups with a sealed envelope and were randomized into three treatments: silicone, Prolene (polypropylene), and otologic T-tube. Ophthalmology and otolaryngology clinics evaluated the patients preoperatively and postoperatively with endoscopes, lacrimal system syringing, and dacryocystography. The success of the stents was evaluated 12 months after surgery with symptom relief and ostial patency. Complications were also noted. Results The overall success rate of the En-DCR in the stent groups was 78.1% (75/96); specifically, 87.5% (28/32) with silicone, 84.4% (27/32) with Prolene, and 62.5% (20/32) with T-tube. The efficacy of the procedures with the T-tube was significantly lower than that of the Prolene and silicone (p = .031, χ2 test). There were no significant differences between the silicone and Prolene (p = .718, χ2 test). Prolene was found to be related with orbital complications. Spontaneous loss is a particular complication of otologic T-tube and highly portends to failure. Conclusions The results of our study suggest that efficacy, defined as anatomic and functional success, is equally high for silicone and Prolene stents and lower for otologic T-tube in En-DCR.
Does Atopy Influence the Effectiveness of Treatment of Adenoid Hypertrophy with Mometasone Furoate?
Authors: Rezende Renato M. , Amato Flávia S. , Barbosa Aline P. , Menezes Ulissis P. , Rezende Patrícia , Ferriani Virgínia P.L. , Anselmo-Lima Wilma T. , Valera Fabiana C. P. 
Published: January 2015

Background The effect of topical mometasone for adenoid hypertrophy treatment is well established. Nevertheless, the influence of atopy on this treatment remains ill defined. Objective This study aims to compare the effects of topical mometasone furoate treatment on the adenoid tissue between atopic and nonatopic children. Methods Fifty-one children with obstructive respiratory complaints underwent a semistructured clinical questionnaire on nasal symptoms, prick test, and nasoendoscopy. Nasoendoscopic images were digitalized, and both adenoid and nasopharyngeal areas were measured in pixels; the relative adenoid/ nasopharyngeal area was calculated. Patients were initially treated for 40 days with nasal saline solution. In a subsequent 40-day period, topical mometasone furoate (total dose, 100 μg/day) was used. Results Topical mometasone significantly improved nasal obstruction, snoring, and apnea and also significantly reduced the adenoid tissue area related to the nasopharynx (p < 0.0001). Treatment with this glucocorticoid was not influenced by atopy, neither for symptoms nor for adenoid area. Conclusion Topical mometasone furoate significantly reduced the adenoid tissue area and led to a supplementary improvement ofnasal symptoms. This improvement was similar for atopic and nonatopic patients.
Staphylococcus Aureus Biofilms Induce Apoptosis and Expression of Interferon-γ, Interleukin-10, and Interleukin-17A on Human Sinonasal Explants
Authors: Cantero Daniel , Cooksley Clare , Bassiouni Ahmed , Tran Hai Bac , Roscioli Eugene , Wormald Peter-John , Vreugde Sarah 
Published: January 2015

Background Staphylococcus aureus is one of the most common bacteria associated with chronic rhinosinusitis (CRS). Although S. aureus biofilms have been correlated with disease severity in CRS, little is known about the initial immune response that biofilms induce in the sinonasal mucosa. Objective The aim of this study was to evaluate the innate immune response (in terms of cytokines) of nondiseased human sinonasal tissue to S. aureus biofilms. Methods Full-thickness sinonasal explant cultures (n = 7 donors) were challenged with established S. aureus biofilms for 24 hours. The expression profiles of 17 cytokines were measured using multiplex analysis, real-time quantitative reverse transcription polymerase chain reaction, and immunohistochemistry. Differences in expression were evaluated using Student's t-test. Results Interleukin (IL)-1β, IL-10, TNF, IL-17A, and interferon (IFN)-γ were up-regulated at the RNA and protein levels in biofilm-treated tissues compared with controls. Elevation of caspase-3 in biofilm-treated samples indicates S. aureus biofilms induce apoptosis on the sinonasal mucosa. Conclusion S. aureus biofilms induced apoptosis and a predominant proinflammatory immune response on normal sinonasal mucosal explants. This immune response appeared to be triggered by intrinsic bacterial elements but also by components of the biofilm matrix. Live biofilms were present on the mucosa at the end of the challenge, suggesting an inability of the induced immune response to eliminate the S. aureus biofilms.
Prevalence of Nasal Polyps and its Risk Factors: Korean National Health and Nutrition Examination Survey 2009-2011
Authors: We Jaewoon , Lee Woo Hyun , Tan Keng Lu , Wee Jee Hye , Rhee Chae-Seo , Lee Chul Hee , Ann Soyeon , Lee Ju Hyun , Kim Jeong-Whun 
Published: January 2015

Background Although nasal polyps (NPs) are thought to be a common otorhinolaryngologic disease, there have been few population-based epidemiologic studies on the prevalence of NPs. The aim of this study is to evaluate the prevalence of NPs and the risk factors in the general Korean population. Methods The data were obtained from the Korea National Health and Nutrition Examination Survey (KNHANES) (2009-2011), which was a cross-sectional survey of noninstitutionalized populations all around the country (n = 28,009). Among them, 19,152 participants (age more than or equal to 20 years) completed medical interviews, physical examinations and endoscopic examination. Analyses were performed using a complex sample design to identify the prevalence and its risk factors. Results The weighted prevalence of NPs was 2.5%. The increased prevalence was associated with increasing age. In the multivariate analyses, male sex [adjusted odds ratio (OR) = 1.68, 95% confidence interval (CI) = 1.25-2.26], low education level (adjusted OR = 1.57, CI = 1.16-2.13), obesity (adjusted OR = 1.49, CI = 1.19-1.87), asthma (adjusted OR = 1.80, CI = 1.24-2.62), and thyroid cancer (adjusted OR = 2.98, CI = 1.26-7.09) were associated with NPs. Among those with NPs, the proportion of symptomatic NPs was 34.4% and asthma was the only significant associated risk factor. Conclusion The prevalence of NPs in the Korean general population was not low despite advances in medical and surgical treatment and two thirds of the subjects with NPs were asymptomatic. Further investigation is needed to exhibit the causal relationship between the associated risk factors identified and NPs.
Tension of the Ulnar, Median, and Radial Nerves During Ulnar Nerve Neurodynamic Testing: Observational Cadaveric Study
Authors: Manvell Nicole , Manvell Joshua J. , Snodgrass Suzanne J. , Reid Susan A. 
Published: January 2015

BackgroundThe ulnar nerve upper limb neurodynamic test (ULNT3) uses upper limb positioning to investigate symptoms arising from the ulnar nerve. It is proposed to selectively increase tension of the nerve; however, this property of the test is not well established.ObjectiveThe aim of this study was to determine the upper limb position that results in: (1) the greatest tension of the ulnar nerve and (2) the greatest difference in tension between the ulnar nerve and the other 2 major nerves of the upper limb: median and radial.DesignThis was an observational cadaver study.MethodsTension (in newtons) of the ulnar, median, and radial nerves was measured simultaneously using 3 buckle force transducers in 5 upper limb positions in 10 embalmed human cadavers (N=20 limbs). Repeated-measures analysis of variance (ANOVA) with Bonferroni post hoc tests determined differences in tension among nerves and among limb positions.ResultsThe addition of shoulder horizontal abduction (H.Abd; 12.62 N; 95% confidence interval [95% CI]=10.76, 14.47) and combined shoulder abduction and internal rotation (H.Abd+IR; 11.86 N; 95% CI=9.96, 13.77) to ULNT3 (scapular depression, shoulder abduction and external rotation, elbow flexion, forearm pronation, and wrist and finger extension) produced significantly greater ulnar nerve tension compared with the ULNT3 alone (8.71 N; 95% CI=7.25, 10.17). The ULNT3+H.Abd test demonstrated the greatest difference in tension among nerves (mean difference between ulnar and median nerves=11.87 N; 95% CI=9.80, 13.92; mean difference between ulnar and radial nerves=8.47 N; 95% CI=6.41, 10.53).LimitationsThese results pertain only to the biomechanical plausibility of the ulnar nerve neurodynamic test and do not account for other factors that may affect the clinical application of this test.ConclusionsThe ULNT3+H.Abd is a biomechanically plausible test for detecting peripheral neuropathic pain related to the ulnar nerve. In situations where the shoulder complex will not tolerate the combination of shoulder external rotation in abduction, performing upper limb neurodynamic tests with internal rotation instead of external rotation is a biomechanically plausible alternative.
Accuracy of direct magnetic resonance imaging-guided placement of drug infusion cannulae
Authors: Chittiboina Prashant , Heiss John D. , Lonser Russell R. 
Published: January 2015

An intraoperative MRI (iMRI)–compatible system has been developed for direct placement of convection-enhanced delivery (CED) cannulae using real-time imaging. To establish the precision and feasibility of this technology, the authors analyzed findings in patients who underwent direct iMRI CED cannula placement.
Three consecutive patients underwent iMRI-guided placement of CED infusion cannulae (6 cannulae) for treatment of diffuse intrinsic brainstem glioma (2 patients) or Parkinson's disease (1 patient). Convective infusion cannulae were guided to the target using the ClearPoint iMRI-based navigation platform (MRI Interventions, Inc.). Placement accuracy was analyzed.
Real-time iMRI during infusion cannula insertion allowed for monitoring of trajectory accuracy during placement. During cannula insertion, no reinsertions or changes due to errors in targeting were necessary. The mean radial error was 1.0 ± 0.5 mm (± SD). There was no correlation between the total length of the planned trajectory and the radial error (Pearson's coefficient: −0.40; p = 0.5). The mean anteroposterior and lateral errors were 0.9 ± 0.5 and 0.3 ± 0.2 mm, respectively. The mean in-plane distance error was 1.0 ± 0.4 mm. The mean tip error (scalar distance between the planned target and actual tip) was 1.9 ± 0.9 mm. There was no correlation between the length of the planned trajectory and any of the measured errors. No complications were associated with cannula placement.
Real-time iMRI-based targeting and monitoring of infusion cannula placement is a safe, effective, and accurate technique that should enable more selective perfusion of brain regions.
Giant intracranial epidermoids: is total removal feasible?
Authors: Aboud Emad , Abolfotoh Mohammad , Pravdenkova Svetlana , Gokoglu Abdulkerim , Gokden Murat , Al-Mefty Ossama 
Published: January 2015

OBJECT
Epidermoid tumors arise from misplaced squamous epithelium and enlarge through the accumulation of desquamated cell debris. Optimal treatment consists of total removal of the capsule; therefore, giant and multicompartmental tumors are particularly challenging. A conservative attitude in handling the tumor capsule is common given concerns about capsule adherence to neurovascular structures, and thus the possibility of recurrence is accepted with the intent of minimizing complications. This study focuses on the outcome of surgery in patients with giant epidermoid tumors for which total capsule removal was the aim.

METHODS
The authors conducted a retrospective analysis of all patients with giant epidermoid tumors treated by the senior author (O.A.), who pursued total removal of the capsule through skull base approaches. Patients were divided into 2 groups: one including patients with de novo tumors and the other consisting of patients who presented with recurrent tumors.

RESULTS
Thirty-four patients had undergone 46 operations, and the senior author performed 38 of these operations in the study period. The average tumor dimensions were 55 × 36 mm, and 25 tumors had multicompartmental extensions. Total removal of the tumor and capsule was achieved with the aid of the microscope in 73% of the 26 de novo cases but in only 17% of the 12 recurrent tumor cases. The average follow-up among all patients was 111 months (range 10–480 months), and the average postsurgical follow-up was 56.8 months (range 6–137 months). There were 4 recurrences in the de novo group, and every case had had a small piece of tumor capsule left behind. One patient died after delayed rupture of a pseudoaneurysm. In the de novo group, the average preoperative Karnofsky Performance Scale (KPS) score was 71.42%, which improved to 87.14% on long-term follow-up. In the group with recurrences, the KPS score also improved on long-term follow-up, from 64.54% to 84.54%. In the de novo group, 3 cases (11.5%) had permanent cranial nerve deficits, and 4 cases (15.4%) had a CSF leak. In the recurrence group, 3 cases (25%) had new, permanent cranial nerve deficits, and 1 (8.3%) had a CSF leak. Two patients in this group developed hydrocephalus and required a shunt.

CONCLUSIONS
Total removal of the capsule of giant epidermoid tumors was achieved in 73% of patients with de novo tumors and was associated with improved function, low morbidity and mortality, and a lower risk of recurrence. Surgery in patients with recurrent tumors was associated with higher morbidity and persistence of the disease.
Endoscopic endonasal resection of skull base chondrosarcomas: technique and early results
Authors: Moussazadeh Nelson , Kulwin Charles , Anand Vijay K. , Ting Jonathan Y. , Gamss Caryn , Iorgulescu J. Bryan , Tsiouris Apostolos John , Cohen-Gadol Aaron A. , Schwartz Theodore H. 
Published: January 2015

OBJECT
The authors of this study sought to report the technique and early clinical outcomes of a purely endonasal endoscopic approach for resection of petroclival chondrosarcomas.

METHODS
Between 2010 and 2014, 8 patients (4 men and 4 women) underwent endonasal endoscopic operations to resect petroclival chondrosarcomas at 2 institutions. The patients' mean age was 44.8 years (range 30–64 years). One of the patients had previously undergone radiation therapy and another a staged craniotomy. Using volumetric software, an independent neuroradiologist assessed the extent of the resections on MRI scans taken immediately after surgery and at the 3-month follow-up. Immediate complications and control of symptoms were also recorded. In addition, the authors reviewed the current literature on surgical treatment of chondrosarcoma.

RESULTS
The mean preoperative tumor diameter and volume were 3.4 cm and 9.8 cm3, respectively. Six patients presented with cranial neuropathies. Endonasal endoscopic surgery achieved > 95% resection in 5 of the 8 patients and < 95% resection in the remaining 3 patients. One of the 6 neuropathies resolved, and the remaining 5 partially improved. One instance of postoperative CSF leakage required a reoperation for repair; no other complications associated with these operations were observed. All of the patients underwent adjuvant radiotherapy.

CONCLUSIONS
According to the authors' experience, the endoscopic endonasal route is a safe and effective approach for the resection of appropriately selected petroclival chondrosarcomas.