bluuebunny/crossref_metadata_2025_split huggingface dataset:
Vectorial secretion of interleukin-8 mediates autocrine signalling in intestinal epithelial cells via apically located CXCR1
Authors: Rossi Oriana , Karczewski Jurgen , Stolte Ellen H , Brummer Robert J M , van Nieuwenhoven Michiel A , Meijerink Marjolein , van Neerven Joost R J , van Ijzendoorn Sven C D , van Baarlen Peter , Wells Jerry M 
Published: October 2013

Abstract

Background
In the intestinal mucosa, several adaptations of TLR signalling have evolved to avoid chronic inflammatory responses to the presence of commensal microbes. Here we investigated whether polarized monolayers of intestinal epithelial cells might regulate inflammatory responses by secreting IL-8 in a vectorial fashion (i.e. apical versus basolateral) depending on the location of the TLR stimulus.

Results
In the Caco-2 BBE model of polarized villus-like epithelium, apical stimulation with TLR2 and TLR5 ligands resulted in the apical secretion of IL-8. The CXCR1 receptor for IL-8 was expressed only on the apical membrane of Caco-2 BBE cells and differentiated epithelial cells in the human small intestine and colon. Transcriptome analyses revealed that Caco-2 BBE cells respond to stimulation with IL-8 supporting the hypothesis that IL-8 induces G protein-coupled receptor signalling.

Conclusions
These results show that IL-8 induces autocrine signalling via an apical CXCR1 in Caco-2 BBE intestinal epithelial cells and that this receptor is also expressed on the apical surface of differentiated human intestinal epithelial cells in vivo, suggesting an autocrine function for IL-8 secreted in the lumen.
Temporal and micro-spatial heterogeneity in the distribution of Anopheles vectors of malaria along the Kenyan coast
Authors: Walker Martin , Winskill Peter , Basáñez María-Gloria , Mwangangi Joseph M , Mbogo Charles , Beier John C , Midega Janet T 
Published: October 2013

AbstractBackgroundThe distribution of anopheline mosquitoes is determined by temporally dynamic environmental and human-associated variables, operating over a range of spatial scales. Macro-spatial short-term trends are driven predominantly by prior (lagged) seasonal changes in climate, which regulate the abundance of suitable aquatic larval habitats. Micro-spatial distribution is determined by the location of these habitats, proximity and abundance of available human bloodmeals and prevailing micro-climatic conditions. The challenge of analysing—in a single coherent statistical framework—the lagged and distributed effect of seasonal climate changes simultaneously with the effects of an underlying hierarchy of spatial factors has hitherto not been addressed.MethodsData onAnopheles gambiaesensu stricto andA. funestuscollected from households in Kilifi district, Kenya, were analysed using polynomial distributed lag generalized linear mixed models (PDL GLMMs).ResultsAnopheline density was positively and significantly associated with amount of rainfall between 4 to 47 days, negatively and significantly associated with maximum daily temperature between 5 and 35 days, and positively and significantly associated with maximum daily temperature between 29 and 48 days in the past (depending onAnophelesspecies). Multiple-occupancy households harboured greater mosquito numbers than single-occupancy households. A significant degree of mosquito clustering within households was identified.ConclusionsThe PDL GLMMs developed here represent a generalizable framework for analysing hierarchically-structured data in combination with explanatory variables which elicit lagged effects. The framework is a valuable tool for facilitating detailed understanding of determinants of the spatio-temporal distribution ofAnopheles. Such understanding facilitates delivery of targeted, cost-effective and, in certain circumstances, preventative antivectorial interventions against malaria.
Molecular relationships between Australian annual wild rice, Oryza meridionalis, and two related perennial forms
Authors: Sotowa Masahiro , Ootsuka Kenta , Kobayashi Yuu , Hao Yin , Tanaka Katsunori , Ichitani Katsuyuki , Flowers Jonathan M , Purugganan Michael D , Nakamura Ikuo , Sato Yo-Ichiro , Sato Tadashi , Crayn Darren , Simon Bryan , Waters Daniel LE , Henry Robert J , Ishikawa Ryuji 
Published: October 2013

Abstract

Background
The perennial, Oryza rufipogon distributed from Asia to Australia and the annual O. meridionalis indigenous to Australia are AA genome species in the Oryza. However, recent research has demonstrated that the Australian AA genome perennial populations have maternal genomes more closely related to those of O. meridionalis than to those found in Asian populations of O. rufipogon suggesting that the Australian perennials may represent a new distinct gene pool for rice.

Results
Analysis of an Oryza core collection covering AA genome species from Asia to Oceania revealed that some Oceania perennials had organellar genomes closely related to that of O meridionalis (meridionalis-type). O. rufipogon accessions from New Guinea carried either the meridionalis-type or rufirpogon-type (like O. rufipogon) organellar genomes. Australian perennials carried only the meridionalis-type organellar genomes when accompanied by the rufipogon-type nuclear genome. New accessions were collected to better characterize the Australian perennials, and their life histories (annual or perennial) were confirmed by field observations. All of the material collected carried only meridionalis-type organellar genomes. However, there were two distinct perennial groups. One of them carried an rufipogon-type nuclear genome similar to the Australian O. rufipogon in the core collection and the other carried an meridionalis-type nuclear genome not represented in the existing collection. Morphologically the rufipogon-type shared similarity with Asian O. rufipogon. The meridionalis-type showed some similarities to O. meridionalis such as the short anthers usually characteristic of annual populations. However, the meridionalis-type perennial was readily distinguished from O. meridionalis by the presence of a larger lemma and higher number of spikelets.

Conclusion
Analysis of current accessions clearly indicated that there are two distinct types of Australian perennials. Both of them differed genetically from Asian O. rufipogon. One lineage is closely related to O. meridionalis and another to Asian O. rufipogon. The first was presumed to have evolved by divergence from O. meridionalis becoming differentiated as a perennial species in Australia indicating that it represents a new gene pool. The second, apparently derived from Asian O. rufipogon, possibly arrived in Australia later.
Biodiversity research in the “big data” era: GigaScience and Pensoft work together to publish the most data-rich species description
Authors: Edmunds Scott C , Hunter Chris I , Smith Vincent , Stoev Pavel , Penev Lyubomir 
Published: October 2013

Abstract
With the publication of the first eukaryotic species description, combining transcriptomic, DNA barcoding, and micro-CT imaging data, GigaScience and Pensoft demonstrate how classical taxonomic description of a new species can be enhanced by applying new generation molecular methods, and novel computing and imaging technologies. This ‘holistic' approach in taxonomic description of a new species of cave-dwelling centipede is published in the Biodiversity Data Journal (BDJ), with coordinated data release in the GigaScience GigaDB database.
Complete genome analysis of a rare human G3P[9] rotavirus posing as an AU-1 like strain
Authors: Theamboonlers Apiradee , Maiklang Ornwalan , Thongmee Thanunrat , Chieochansin Thaweesak , Vuthitanachot Viboonsuk , Poovorawan Yong 
Published: October 2013

Abstract

Background
We performed phylogenetic and sequence analysis by Basic Local Alignment Search Tool (BLAST) of a complete Human Rotavirus (HRV) genome isolated from a hospitalized child with acute gastroenteritis in Thailand.

Findings
The results indicated an uncommon strain characterized by multiple re-assortments in the VP3, VP4, VP6, NSP1, NSP4 and NSP5 genes. The uncommon strain is genotype G3-P[9]-I3-R3-C3-M3-A3-N3-T3-E3-H6, which displays aspects of the AU-1, FRV-1 and corresponds to the feline/canine prototype G3P[9] strain.

Conclusions
The results suggested that nearly all the eleven gene segments of G3P[9] RVA strain CU365 might have originated from feline/canine RVAs (Rotavirus A).
Statistically optimized biotransformation protocol for continuous production of L-DOPA using Mucuna monosperma callus culture
Authors: Inamdar Shrirang Appasaheb , Surwase Shripad Nagnath , Jadhav Shekhar Bhagwan , Bapat Vishwas Anant , Jadhav Jyoti Prafull 
Published: October 2013

Abstract
L-DOPA (3,4-dihydroxyphenyl-L-alanine), a modified amino acid, is an expansively used drug for the Parkinson’s disease treatment. In the present study, optimization of nutritional parameters influencing L-DOPA production was attempted using the response surface methodology (RSM) from Mucuna monosperma callus. Optimization of the four factors was carried out using the Box–Behnken design. The optimized levels of factors predicted by the model include tyrosine 0.894 g l-1, pH 4.99, ascorbic acid 31.62 mg l-1and copper sulphate 23.92 mg l-1, which resulted in highest L-DOPA yield of 0.309 g l-1. The optimization of medium using RSM resulted in a 3.45-fold increase in the yield of L-DOPA. The ANOVA analysis showed a significant R
2 value (0.9912), model F-value (112.465) and probability (0.0001), with insignificant lack of fit. Optimized medium was used in the laboratory scale column reactor for continuous production of L-DOPA. Uninterrupted flow column exhibited maximum L-DOPA production rate of 200 mg L-1 h-1 which is one of the highest values ever reported using plant as a biotransformation source. L-DOPA production was confirmed by HPTLC and HPLC analysis. This study demonstrates the synthesis of L- DOPA using Mucuna monosperma callus using a laboratory scale column reactor.
Relationship Organization and Price Delegation: An Experimental Study
Authors: Lim Noah , Ham Sung H. 
Published: October 2013

Price delegation to the salesforce is a practice widely adopted by firms. This paper examines the relationship between price delegation and managerial profits using a laboratory economics experiment. A novel feature of our experiment is that we study how varying the relationship organization of the sales manager and salesperson to allow for (1) requests by the salesperson for the manager to choose price delegation, and for (2) the manager to award a small bonus after observing the salesperson's decisions, can affect behavior. The results show that, contrary to the theoretical prediction, managers choose price delegation frequently and salespeople respond reciprocally, leading to higher manager profits under price delegation. Moreover, this behavior increases when requests and bonuses are allowed. We show that a behavioral economics model that incorporates positive reciprocity can explain these results well. Data, as supplemental material, are available at http://dx.doi.org/10.1287/mnsc.2013.1778 . This paper was accepted by Pradeep Chintagunta, marketing.
Hardwood Lumber Buyer Purchase Attributes and Relationships with Suppliers
Authors: Dasmohapatra Sudipta , Gonzalez Ronalds W. 
Published: October 2013

The purpose of this study was to examine product and supplier attributes that influence purchase decisions of hardwood lumber buyers in the United States. Specifically, this article explores the influence of buyer–seller relationships compared with other attributes. Results of an electronic survey of 78 hardwood lumber buyers in the United States (National Hardwood Lumber Association's hardwood lumber buyers list) show that product quality, followed by relationship with suppliers, overall service, and price are the top four attributes that affect purchase decisions.
Respondent hardwood lumber buyers purchased more than 50 percent of their lumber volume in 2006 from their top two suppliers (Supplier 1 accounted for about 32% and Supplier 2 accounted for 19% of the total purchase volume). When comparing their top supplier with their second most important supplier, buyers indicated that the top supplier provided higher overall satisfaction, seemed more willing to invest resources and time, and had a greater long-term focus. Our results indicate that unless a supplier is the top supplier, opportunities for partnership and future profitability may not be realized.
Edge Reinforcement of Honeycomb Sandwich Panels
Authors: Sam-Brew Solace , Semple Kate , Smith Gregory D. 
Published: October 2013

Protection of the fragile honeycomb core material in hollow-core panels has long been a subject of interest for the manufacturers because it is necessary to seal the panel edges to prevent damage. Traditionally this has been accomplished by using edge banding, which has the added benefit of improving panel bending strength and stiffness. This study focuses on evaluating the effects of edge banding on the bending strength and stiffness properties of honeycomb core panels. The honeycomb panels were made with a combination of different face sheet materials (3-mm hardboard or 6-mm medium-density fiberboard [MDF]), rail types (particleboard or yellow poplar [Liriodendron tulipifera]), and rail widths (10 or 38 mm), and had edge-band materials fixed to their long edges using either direct coating, stabilizer edge, or surface folding techniques.
Panels made with the 6-mm MDF face sheet and 38-mm poplar rails had the highest strength properties. To safely apply edge banding to honeycomb core panels, a solid edge reinforcement material is required to prevent the core material from being crushed during the process. The surface folding technique was the best method of edge banding and significantly enhanced the maximum bending moment of honeycomb core panels—more than twice that of panels without edge banding.
Influence of the Lunar Phase of Tree Felling on Humidity, Weight Densities, and Shrinkage in Hardwoods (Quercus humilis)
Authors: Villasante Antonio , Vignote Santiago , Ferrer David 
Published: October 2013

The influence of the lunar phase of tree felling on the properties of wood has been debated for centuries, but it is only recently that it has been the subject of rigorous study. These scientific studies have essentially focused on softwoods, leaving unanswered the question of whether hardwoods follow the same pattern.
This article presents the results of the analysis of the lunar influence of the felling date on the humidity, specific weights, and shrinkage of wood. The random sample analyzed consists of 60 oaks (Quercus humilis Mill.) felled during the four lunar phases (15 trees per phase) throughout one lunar period. No significant differences were detected in any of the cases.
Fully Mechanized Harvesting in Aged Oak Coppice Stands
Authors: Suchomel Christian , Becker Gero , Pyttel Patrick 
Published: October 2013

Coppice is a traditional forest management system used all over the world. It takes advantage of fast early growth and the vegetative reproduction of the respective trees. Coppice forests provide firewood and many other products and services, especially to rural communities. In Central Europe, regular periodic cutting and management of coppice forests was abandoned due to socioeconomic changes in recent decades, resulting in aged stands that have gradually lost their coppice characteristics. Today, coppice forests are recognized again not only for their growth potential but also for their benefits for biodiversity and nature conservation. Together with the rising demand for energy wood, this recognition could result in a renaissance of the traditional coppice management system. Several stands grow on relatively easily accessible terrain where fully mechanized systems (harvester, forwarder) could be used. However, there is no current information regarding the technical feasibility and productivity of modern harvester technology used in coppice forests.
In this study, an HSM 405H 6WD harvester with an CTL 40HW processor head was investigated with time studies to determine technical feasibility and time consumption of harvesting aged oak coppice. The results show high productivity for harvesting hardwood. The multiple stem structure that is typical for coppice forests does not result in technical problems or significantly higher time consumption for the harvester, even though it is slightly more time-consuming to grab and fell multi-stem trees than a single tree. Compared with a forest worker with a chainsaw, the harvester left significantly (5 cm) higher stools.
Characteristics of Wood Fuel Pellet Manufacturers and Markets in the United States, 2010
Authors: Lu Ning , Rice Robert W. 
Published: October 2013

The wood fuel pellet industry has been growing rapidly in recent years. The survey results reported here are focused on the annual production, raw material, production cost rankings, market radius, barriers to market expansion, and other data that give an overview of the industry during a very difficult economic period. Eighty-four mills across the United States were contacted and 53 responded. The average volume of production was over 59,000 tons per year. Raw materials for pelletizing and labor were the principal costs of production according to respondents. Market demand and capital costs were cited as the chief barriers to expansion.
The industry is clearly subject to market forces that influence the cost and availability of raw materials as well as the cost of heating fuel alternatives such as oil. Despite the economic difficulties, demand continues to grow for pellet fuels both in the United States and in Europe.
Impact of Wood Variability on the Drying Rate at Different Moisture Content Levels
Authors: Berberović Adin , Milota Michael R. 
Published: October 2013

The impacts on drying behavior of basic density, initial moisture content, percentage and position of heartwood, ring count, rings from the pith, growth ring angle, and earlywood and latewood coverage on board faces were investigated for western hemlock (Tsuga heterophylla) lumber. Mathematical relations for the effects of wood properties and board geometric features related to position within its parental log were developed to predict the drying rate at four moisture content levels for drying temperatures of 80°C and 115°C. These relations were used for simulating wood drying as well as for predicting drying times of individual boards, which were used as a criterion for sorting green boards prior to entering their properties in the drying simulation.
Drying rate was affected by basic density, initial moisture content, percent heartwood, and growth ring angle at 80°C and only initial moisture content at 115°C. Presorting into two groups based on these wood properties reduced the standard deviation of the final moisture content distribution by 40 percent.
A Field-Tested Log Traceability System
Authors: Möller Björn , Wikander Jan , Hellgren Mikael 
Published: October 2013

Today, an information gap exists between log measurements performed in the forest and at the sawmill. By applying a code in the forest during harvesting and then reading it at the sawmill, this information gap would vanish. A log applicator, which applies two-dimensional log codes through the saw bar, and a corresponding detection system based on vision technology have been developed. Key features of this technology are the very low cost of each mark and the zero-time-loss characteristic of both marking and detection.
A field test utilizing this equipment was performed on 210 logs in northern Sweden in December 2009. For logs harvested during real harvesting conditions and automatically detected at the log sorting station of a running sawmill, a detection rate of 40 percent was achieved. A comparison between parameters (length and diameter) measured in the forest and at the sawmill is presented, as are a number of suggested improvements to increase the detection rate substantially.
Effects of End Plates on Reducing Checking of Pentachlorophenol-Treated Douglas-Fir Crossarms
Authors: Love Connie S , Morrell Jeffrey J. 
Published: October 2013

Abstract
The effect of metal end plates on reducing checking of pentachlorophenol-treated Douglas-fir crossarms was evaluated over 13 wet–dry cycles. Check development was variable over the first three to four cycles, and then steadily increased for both plated and nonplated ends of arms; however, both the number of checks and the maximum width of the checks were significantly lower on plated ends. The results suggest that end plating reduces the potential for deep check development in crossarms that could lead to early failure.
Veneer-Reinforced Particleboard for Exterior Structural Composition Board
Authors: Hse Chung Y. , Shupe Todd F. , Pan Hui , Feng Fu 
Published: October 2013

Abstract
Two experiments were performed to determine the physical and mechanical characteristics of panels consisting of a veneer face and a particleboard core composed of mixed wood particles/powdered-recycled polyethylene (PE) bag waste (MWP) using urea-formaldehyde (UF) resin as a binder. The addition of 25 percent powdered-recycled PE bag waste to the MWP panels did not adversely affect nonaged bonding strength but did result in substantial improvement in internal bond (IB) retention after a 24-hour water soak and improved dimensional stability. Average MWP panel IB retention was more than 300 percent higher than the IB retention of wood particle (WP) panels and MWP thickness swell and linear expansion were 70 and 44 percent lower, respectively, than the values for WP panels. For the veneer overlay composite, the mean modulus of rupture (MOR) parallel to the surface grain veneer (MOR||) was lowest (3,668.2 pounds per square inch [psi]) for panels with two veneers cross-laminated on each face over a WP core. Conversely, MOR|| was greatest (8,535.6 psi) for panels with single 1/8-inch veneers on each face over an MWP core. However, the large percentage of shear failure when stressed parallel to face veneer grain hindered an accurate determination of true MOR. As expected, all specimens tested in bending parallel to the surface grain of the veneers resulted in higher modulus of elasticity (MOE) than those tested perpendicular to the grain. For a single veneer overlay on each face, it is interesting to note that thinner veneers (i.e., 1/8 in.) resulted in higher MOE than thicker veneers (i.e., 3/16 in.).
Comparative Study of the Storage Stability between a Melamine-Urea-Formaldehyde and a Urea-Formaldehyde Resin
Authors: Lee Sang-Min , Park Jong-Young , Park Sang-Bum , Han Seung-Tak , Kang Eun-Chang 
Published: October 2013

Abstract
Amino resin wood adhesives used for medium-density fiberboard (MDF), a melamine-urea-formaldehyde (MUF) resin and a urea-formaldehyde (UF) resin, were each synthesized with an overall formaldehyde/urea molar ratio of 1.10. The storage stability of the resins was monitored by their gel times and viscosity changes, as well as by a multiple light scattering method. The storage stability tended to be affected by the temperature at which the resins were stored. MUF resin had a higher storage stability at a storage temperature above room temperature, whereas UF resin exhibited the best storage stability at 10°C with overall good stability at all tested temperatures from 10°C to 40°C.