bluuebunny/crossref_metadata_2025_split huggingface dataset:
Global trend and hotspot of resin materials for dental caries repair: a bibliometric analysis
Authors: Han Baodi , Wang Lian 
Published: June 2024

ObjectiveThe objective of this study is to explore the current research status, key areas, and future development trends in the field of resin materials for dental caries repair through an objective and quantitative analysis of the literature.MethodsA search was conducted on the Web of Science Core Collection using “dental cavity” and “resin” as keywords, covering the period from 2000 to 2023. Data including author names, journals, countries, institutions, keywords, and citation rates were extracted. The collected data was subjected to statistical analysis using bibliometrics methodology, and visual knowledge maps were generated using software like CiteSpace 6.2.R4, Microsoft365, and R.ResultsA total of 4800 articles were retrieved, involving 13,423 authors, 2654 institutions, 76 countries, and 560 journals. The number of publications and cumulative publications in this field showed an increasing trend, reaching a peak in 2022. Dental Materials was the journal with the highest number of publications, cumulative publications, and citation rates. XU HHK was the most prolific author in terms of publications and citations. The University of Maryland was the institution with the highest number of publications. Brazil was the country with the highest number of publications. The USA had the highest level of collaboration with other countries. Collaboration between different authors, institutions, and countries in this field was relatively close, which contributed to the rapid development of resin materials for caries repair. The current research focus is mainly on the nature of dental caries, characteristics of resin materials, and bonding strength of adhesives. Enhancing the bioactivity and remineralization of resin materials, advanced antibacterial strategies, longevity and durability of resin restorations, nanotechnology, and material innovation, as well as digital dentistry, will receive increased attention as future research trends.ConclusionResin materials for dental caries repair have received significant attention. Future research should combine nanotechnology and big data analysis to investigate the mechanisms of dental caries occurrence and development, enhance the performance and longevity of resin materials, and conduct high-quality, large-scale empirical research.
Visual and refractive outcomes of opposite clear corneal incision combined with rotationally asymmetric multifocal intraocular lens implantation
Authors: Qin Xiaoyu , Yao Pengxiang , Wu Xinyuan , Wu Yang , Hong Yufang , Chen Zhenzong , Yuan Yuanzhi 
Published: June 2024

PurposeTo evaluate the visual and refractive outcomes of astigmatic cataract patients following opposite clear corneal incision (OCCI) combined with rotationally asymmetric multifocal intraocular lens (IOL) implantation.SettingDepartment of Ophthalmology, Zhongshan Hospital (Xiamen), Fudan University, People’s Republic of China.DesignRetrospective cohort study.MethodsThis study comprised 58 cataract eyes of 54 patients with corneal astigmatism who underwent phacoemulsification and rotationally asymmetric multifocal IOL implantation which received either OCCI (OCCI group) or a single clear corneal incision (SCCI group). The follow-up period was 3 months after surgery. Distance, intermediate and near visual acuity, refractive outcomes, and corneal anterior keratometry were compared between the two groups. Vector analysis was used to evaluate astigmatism correction.ResultsThree months after surgery, the distance, intermediate and near visual acuity, and sphere remained comparable between the two groups, but a significant difference was detected in residual astigmatism and anterior corneal keratometric astigmatism. In the OCCI group, the residual astigmatism and keratometric astigmatism were −0.60 ± 0.29 D and 0.59 ± 0.28 D, respectively, which were lower than those in SCCI groups (−1.18 ± 0.47 D and 1.15 ± 0.45 D, both p &lt; 0.05). In vector analysis, the difference vector (DV), angle of error (AoE), absolute AoE, index of success (IoS) and correction index (CI) were statistically significantly different between the two groups (p &lt; 0.05).ConclusionOCCI combined with rotationally asymmetric multifocal intraocular lens implantation showed predictable and desirable efficacy in treating cataract patients with astigmatism.
Comparative analysis of obstetric, perinatal, and neurodevelopmental outcomes following chorionic villus sampling and amniocentesis
Authors: Kim Nari , Joo Eun Hui , Kim Seoyeon , Kim Taeho , Ahn Eun Hee , Jung Sang Hee , Ryu Hyun Mee , Lee Ji Yeon 
Published: June 2024

BackgroundThe risks of invasive prenatal tests are reported in previous studies such as miscarriage, fetal anomalies, and bleeding. However, few compare short-term and long-term outcomes between invasive tests. This study aims to investigate obstetric, perinatal, and children’s neurodevelopmental outcomes following chorionic villus sampling (CVS) or amniocentesis in singleton pregnancy.MethodsThis retrospective cohort study included healthy singleton pregnancies underwent transabdominal CVS (gestational age [GA] at 10–13 weeks) or amniocentesis (GA at 15–21 weeks) at a single medical center between 2012 and 2022. Only cases with normal genetic results were eligible. Short-term and long-term neurodevelopmental outcomes were evaluated.ResultsThe study included 200 CVS cases and 498 amniocentesis cases. No significant differences were found in body mass index, parities, previous preterm birth, conception method, and cervical length (CL) before an invasive test between the groups. Rates of preterm labor, preterm premature rupture of the membranes, preterm birth, neonatal survival, neonatal short-term morbidities, and long-term neurodevelopmental delay were similar. However, the CVS group had a higher rate of cervical cerclage due to short CL before 24 weeks (7.0%) compared to the amniocentesis group (2.4%). CVS markedly increased the risk of cervical cerclage due to short CL (adjusted odd ratio [aOR] = 3.17, 95%CI [1.23–8.12], p = 0.016), after considering maternal characteristics.ConclusionPerforming CVS resulted in a higher incidence of cerclage due to short cervix or cervical dilatation compared to amniocentesis in singleton pregnancies. This highlights the importance of cautious selection for CVS and the necessity of informing women about the associated risks beforehand.
A novel Enterococcus faecium phage EF-M80: unveiling the effects of hydrogel-encapsulated phage on wound infection healing
Authors: Khazani Asforooshani Mahshid , Elikaei Ameneh , Abed Sahar , Shafiei Morvarid , Barzi Seyed Mahmoud , Solgi Hamid , Badmasti Farzad , Sohrabi Aria 
Published: June 2024

BackgroundEnterococcus faecium is one of the members of ESKAPE pathogens. Due to its resistance to antimicrobial agents, treating this bacterium has become challenging. The development of innovative approaches to combat antibiotic resistance is necessary. Phage therapy has emerged as a promising method for curing antibiotic-resistant bacteria.MethodsIn this study, E. faecium phages were isolated from wastewater. Phage properties were characterized through in vitro assays (e.g. morphological studies, and physicochemical properties). In addition, whole genome sequencing was performed. A hydrogel-based encapsulated phage was obtained and its structure characteristics were evaluated. Wound healing activity of the hydrogel-based phage was assessed in a wound mice model.ResultsThe purified phage showed remarkable properties including broad host range, tolerance to high temperature and pH and biofilm degradation feature as a stable and reliable therapeutic agent. Whole genome sequencing revealed that the genome of the EF-M80 phage had a length of 40,434 bp and harbored 65 open reading frames (ORFs) with a GC content of 34.9% (GenBank accession number is OR767211). Hydrogel-based encapsulated phage represented an optimized structure. Phage-loaded hydrogel-treated mice showed that the counting of neutrophils, fibroblasts, blood vessels, hair follicles and percentage of collagen growth were in favor of the wound healing process in the mice model.ConclusionThese findings collectively suggest the promising capability of this phage-based therapeutic strategy for the treatment of infections associated with the antibiotic-resistant E. faecium. In the near future, we hope to expect the presence of bacteriophages in the list of antibacterial compounds used in the clinical settings.
A synbiotic mixture of Bifidobacterium breve M16-V, oligosaccharides and pectin, enhances Short Chain Fatty Acid production and improves lung health in a preclinical model for pulmonary neutrophilia
Authors: Bezemer Gillina F. G. , Diks Mara A. P. , Mortaz Esmaeil , van Ark Ingrid , van Bergenhenegouwen Jeroen , Kraneveld Aletta D. , Folkerts Gert , Garssen Johan 
Published: June 2024

IntroductionPulmonary neutrophilia is a hallmark of numerous airway diseases including Chronic Obstructive Pulmonary Disease (COPD), Neutrophilic asthma, Acute Lung Injury (ALI), Acute Respiratory Distress Syndrome (ARDS) and COVID-19. The aim of the current study was to investigate the effect of dietary interventions on lung health in context of pulmonary neutrophilia.MethodsMale BALB/cByJ mice received 7 intra-nasal doses of either a vehicle or lipopolysaccharides (LPS). To study the effect of nutritional interventions they received 16 intra-gastric doses of either a vehicle (PBS) or the following supplements (1) probiotic Bifidobacterium breve (B. breve) M16-V; (2) a prebiotic fiber mixture of short-chain galacto-oligosaccharides, long-chain fructo-oligosaccharides, and low-viscosity pectin in a 9:1:2 ratio (scGOS/lcFOS/lvPectin); and (3) A synbiotic combination B. breve M16-V and scGOS/lcFOS/lvPectin. Parameters for lung health included lung function, lung morphology and lung inflammation. Parameters for systemic immunomodulation included levels of fecal short chain fatty acids and regulatory T cells.ResultsThe synbiotic supplement protected against the LPS induced decline in lung function (35% improved lung resistance at baseline p = 0.0002 and 25% at peak challenge, p = 0.0002), provided a significant relief from pulmonary neutrophilia (40.7% less neutrophils, p &lt; 0.01) and improved the pulmonary neutrophil-to-lymphocyte ratio (NLR) by 55.3% (p = 0.0033). Supplements did not impact lung morphology in this specific experiment. LPS applied to the upper airways induced less fecal SCFAs production compared to mice that received PBS. The production of acetic acid between day −5 and day 16 was increased in all unchallenged mice (PBS-PBS p = 0.0003; PBS-Pro p &lt; 0.0001; PBS-Pre, p = 0.0045; PBS-Syn, p = 0.0005) which upon LPS challenge was only observed in mice that received the synbiotic mixture of B. breve M16-V and GOS:FOS:lvPectin (p = 0.0003). A moderate correlation was found for butyric acid and lung function parameters and a weak correlation was found between acetic acid, butyric acid and propionic acid concentrations and NLR.ConclusionThis study suggests bidirectional gut lung cross-talk in a mouse model for pulmonary neutrophilia. Neutrophilic lung inflammation coexisted with attenuated levels of fecal SCFA. The beneficial effects of the synbiotic mixture of B. breve M16-V and GOS:FOS:lvPectin on lung health associated with enhanced levels of SCFAs.
Development and validation of the BMQ-AIR©: a screening tool for assessing patients’ treatment beliefs about switching to anti-inflammatory reliever (AIR) therapy
Authors: Foot Holly , Chan Amy Hai Yan , Horne Rob 
Published: June 2024

IntroductionDespite anti-inflammatory reliever (AIR) therapy now being the preferred treatment choice across all severities of asthma, many patients are still “attached” to their short-acting beta2-agonist (SABA) reliever, believing this to be the best way to control their asthma. To encourage individuals to switch to AIR, it is important to first identify the beliefs that patients hold about AIR.ObjectiveThe aim of this paper was to describe the initial development and validation of the BMQ-AIR©, a six-item screening tool which assesses and identifies patients’ treatment beliefs about switching to AIR therapy.MethodsStatements were identified from the primary literature that assessed patients’ perceptions of AIR therapy and adapted from the Beliefs about Medicines Questionnaire (BMQ). Internal reliability was examined using Cronbach’s alpha coefficient. Construct validity was evaluated by comparing scores on BMQ-AIR© with a validated measure of medication adherence and SABA beliefs.ResultsA total of 446 participants completed the online survey. The BMQ-AIR© contained two subscales with three items each. Both the Necessity and Concerns subscales demonstrated good internal reliability, with Cronbach’s α-values of 0.70 and 0.69, respectively. Both subscales were negatively correlated with self-report inhaled corticosteroid adherence (Necessity: r = −0.28, p &lt; 0.0001; Concerns: r = −0.28, p &lt; 0.0001) and positively correlated with SRQ scores (Necessity: r = 0.51, p &lt; 0.0001; Concerns: r = 0.44, p &lt; 0.0001).ConclusionPreliminary findings indicate that BMQ-AIR© demonstrates satisfactory reliability and validity. BMQ-AIR© is a promising tool that may help tailor interventions to an individual’s specific beliefs and barriers to switching to better support individuals in stopping SABA and initiating AIR therapy.
Clinical efficacy of Osteoking in knee osteoarthritis therapy: a prospective, multicenter, non-randomized controlled study in China
Authors: Zhou Jun , Zheng Zelu , Luo Yuxin , Dong Yawei , Yan Yan , Zhang Yi , Tang Kaiqiang , Quan Rui , Lin Jiaming , Zhang Kuayue , Dong Pengxuan , Wang Rongtian , He Haijun , Lin Na , Weng Xisheng , Mi Baohong , Zhang Yanqiong , Chen Weiheng 
Published: June 2024

BackgroundOsteoking has been extensively used for the treatment of knee osteoarthritis (KOA). However, it is lack of high-quality evidence on the clinical efficacy of Osteoking against KOA and the comparison with that of nonsteroidal anti-inflammatory drugs (NSAIDs).AimsTo evaluate the efficacy and safety of Osteoking in treating KOA.MethodsIn the current study, a total of 501 subjects were recruited from 20 medical centers, and were divided into the Osteoking treatment group (n = 428) and the NSAIDs treatment group (n = 73). The Propensity Score Matching method was used to balance baseline data of different groups. Then, the therapeutic effects of Osteoking and NSAIDs against KOA were evaluated using VAS score, WOMAC score, EQ-5D-3L and EQ-VAS, while the safety of the two treatment were both assessed based on dry mouth, dizziness, diarrhea, etc.ResultsAfter 8 weeks of treatment, the Osteoking group was compared with the NSAIDs group, the VAS score [2.00 (1.00, 3.00) vs. 3.00 (2.00, 4.00)], WOMAC pain score [10.00 (8.00, 13.00) vs. 11.00 (8.00, 16.00) ], WOMAC physical function score [32.00 (23.00, 39.00) vs. 39.07 ± 16.45], WOMAC total score [44.00 (31.00, 55.00) vs. 53.31 ± 22.47) ], EQ-5D-3L score [0.91 (0.73, 0.91) vs. 0.73 (0.63, 0.83) ] and EQ-VAS score [80.00 (79.00, 90.00) vs. 80.00 (70.00, 84.00) ] were improved by the treatment of Osteoking for 8 weeks more effectively than that by the treatment of NSAIDs. After 8 weeks of treatment with Osteoking, the VAS scores of KOA patients with the treatment of Osteoking for 8 weeks were reduced from 6.00 (5.00, 7.00) to 2.00 (1.00, 3.00) (p &lt; 0.05), which was better than those with the treatment of NSAIDs starting from 2 weeks during this clinical observation. Importantly, further subgroup analysis revealed that the treatment of Osteoking was more suitable for alleviating various clinical symptoms of KOA patients over 65 years old, with female, KL II-III grade and VAS 4-7 scores, while the clinical efficacy of NSAIDs was better in KOA patients under 65 years old and with VAS 8–10 scores. Of note, there were no differences in adverse events and adverse reactions between the treatment groups of the two drugs.ConclusionOsteoking may exert a satisfying efficacy in relieving joint pain and improving life quality of KOA patients without any adverse reactions, especially for patients with KL II-III grades and VAS 4–7 scores.Clinical Trial Registration:https://www.chictr.org.cn/showproj.html?proj=55387, Identifier ChiCTR2000034475
Effects of structured and unstructured interventions on fundamental motor skills in preschool children: a meta-analysis
Authors: Chen Delong , Zhao Guanggao , Fu Jinmei , Shun Sunli , Su Liqiang , He Zihao , Chen Ruiming , Jiang Tianle , Hu Xuewen , Li Yunong , Shen Fanchao 
Published: June 2024

BackgroundIt has been suggested that higher levels of fundamental motor skills (FMS) promote the physical health of preschool-aged children. The impacts of structured and unstructured interventions on FMS in children aged 10–16 years have been widely acknowledged in previous studies. However, there is a lack of relevant studies in preschool-aged children.ObjectiveThis meta-analysis aimed to compare the effects of structured and unstructured interventions on FMS in preschool-aged children.MethodsThe PubMed, Web of Science, and Google Scholar databases were searched from inception to 1 November 2023 to identify experiments describing structured and unstructured interventions for FMS in preschool-aged children. The Downs and Black Checklist was used to assess the risk of bias. A random effects model was used for the meta-analysis to evaluate the pooled effects of interventions on FMS. Subgroup analyses based on the duration and characteristics of the intervention were conducted to identify sources of heterogeneity.ResultsA total of 23 studies with 4,068 participants were included. There were 12 studies examining structured interventions, 9 studies examining unstructured interventions, and 6 studies comparing structured vs. unstructured interventions. The risk of bias in the included studies was generally low. All interventions significantly improved FMS in preschool-aged children compared to control treatments (p &lt; 0.05). Structured interventions had more significant effects on locomotor skills (LMSs) in preschool-aged children than unstructured interventions (Hedges’ g = 0.44, p = 0.04). The effects of structured interventions were strongly influenced by the total intervention duration, such that long-term interventions were more effective (Hedge’s g = 1.29, p &lt; 0.001).ConclusionStructured interventions play a crucial role in enhancing FMS among young children, especially when considering LMSs. These interventions require consistent and repeated practice over time to reach proficiency.Systematic review registration:PROSPERO, identifier number CRD42023475088, https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023475088.
ƯỚC LƯỢNG TỐC ĐỘ LUỒNG GIAO THÔNG TRÊN VIDEO GIAO THÔNG SỬ DỤNG YOLOV8 VÀ BYTETRACK
Authors: Phương Vũ Lê Quỳnh , Khang Phạm Nguyên , Thư Trần Nguyễn Minh 
Published: June 2024

Lưu lượng giao thông là một lĩnh vực quan trọng trong sự phát triển của kinh tế, xã hội và môi trường. Để đánh giá lưu lượng giao thông, việc ước lượng tốc độ luồng giao thông là quan trọng. Trong bài nghiên cứu này, chúng tôi đề xuất một mô hình ước lượng tốc độ luồng giao thông dựa trên dữ liệu thu thập từ các camera giám sát giao thông. Mục tiêu chính là đếm và theo dõi các phương tiện để ước lượng lưu lượng giao thông bằng cách kết hợp mô hình Yolov8 và ByteTrack, sau đó tính toán tốc độ trung bình của các phương tiện. Để huấn luyện và đánh giá hiệu suất của mô hình, dữ liệu thu thập từ Công an phường Vĩnh Thanh Vân – Thành phố Rạch Giá, bao gồm 10 092 ảnh và hơn 96 024 đối tượng được gán nhãn trong nhiều điều kiện khác nhau được sử dụng. Trong nghiên cứu đã thử nghiệm và so sánh hiệu suất của mô hình của mình với các mô hình kết hợp Yolov8 và DeepSort. Kết quả thực nghiệm cho thấy rằng mô hình đề xuất có thời gian thực thi thấp nhất và có khả năng ước lượng lưu lượng giao thông gần với thực tế, với độ chính xác là 91,39%. Bộ dữ liệu sử dụng trong nghiên cứu này có thể được nghiên cứu sử dụng như một tập kiểm thử đối với các bài toán tương tự.
Memory in Philosophy of Religion
Authors: Briedis Mindaugas 
Published: June 2024

This article analyzes the notion of memory in the philosophy of religion. The area of this problematic is defined by Descartes, who, in a thought experiment, postulates an all-powerful, evil demon capable of falsifying human perception. The problem of solipsism raised here also implies doubt about claims based on memory. Descartes’ assumptions are taken up constructively by Alvin Plantinga in his attempt to solve problems in the epistemology of religion by raising the following new question: is belief in God rational, and, if so, is it justified? Peter van Inwagen, for his part, uses memory analysis to construct arguments in support of theodicy. In considering these issues, other key topics within the philosophy of religion, such as the afterlife and the existence of the soul, which are closely related to the analysis of personal identity, inevitably arise.
Efficacy of Keratinolytic Bacteria (Bacillus pumilus) for decomposing non-sparingly degradable poultry feathers from waste to wealth
Authors: Aishwath Om Prakash , Jangir Chetan Kumar , Manglani Neetu 
Published: June 2024

There is a growing need for economical and environmentally responsible ways to valorizing poultry feather waste, and keratinolytic bacteria show significant promise. A single strain of Bacillus pumilus NM03, which was isolated from living poultry and has been shown to have substantial keratinolytic characteristics, degrades feathers. In this work, the effects of temperature on the quality of compost prepared with wheat and coriander straw were assessed both alone and in combination with thermophilic microbial inoculation. Temperature @ 37°C + inoculum significantly reduced total nitrogen loss (56.20 and 69.80%) and total organic carbon degradation (47.06 and 62.41%) in coriander and wheat straw composting, respectively, when compared to temperature @37°C. For different regression models, the higher and lower R2 values were estimated for the linear-linear and log logistic models for coriander with feather composting, and the linear-linear and linear models for wheat with feather composting, respectively. The principal component loading matrix obtained from correlation matrix reveals that the first three components whose eigen values are greater than 1, together account for about 91.70% and 87.69 % of the total explained variance in coriander and wheat with feather composting, respectively. Furthermore, our results showed that temperature @ 37°C + inoculum were most suited for feather composting with wheat and coriander straw for total organic carbon and total nitrogen breakdown was expedited for increased bacterial richness and diversity, as well as Bacillus pumilus overrepresentation. The quality of end-product obtained based on final C: N ratio coriander compost with feathers was found to be the best supplement for composting of such highly keratinoluytic waste.
PREPARATION OF STATE AVIATION FLIGHT PERSONNEL FOR SURVIVAL IN EXTREME ENVIRONMENTAL CONDITIONS
Authors: Бородин Сергей Константинович 
Published: June 2024

Работа посвящена проблемам подготовки летного состава государственной авиации к выживанию в условиях экстремальной природной среды. Рассмотрены факторы и условия, влияющие на благоприятный исход выживания. На примере одного из факторов выживания показаны взаимосвязь и взаимозависимость различных элементов подготовки летчика на успех выживания. Обоснована необходимость системного подхода в вопросах данного вида подготовки летного состава.
The work is devoted to the problems of training the flight personnel of state aviation to survive in an extreme natural environment. The factors and conditions affecting the favorable outcome of survival are considered. Using the example of one of the survival factors, the interrelation and interdependence of various elements of pilot training for survival success are shown. The necessity of a systematic approach to the issues of this type of training of flight personnel is substantiated.