bluuebunny/crossref_metadata_2025_split huggingface dataset:
À la recherche du français en Nouvelle-Angleterre: une enquête de terrain à travers six États
Authors: SALMON CAROLE , DUBOIS SYLVIE 
Published: September 2013

RÉSUMÉL'héritage francophone américain qui a survécu à la traversée du 21èmesiècle se retrouve essentiellement en Louisiane et en Nouvelle-Angleterre. Cet article propose une description de la communauté francophone de la Nouvelle-Angleterre et d'une enquête sur le terrain au cours de laquelle chaque état a révélé un profil communautaire original. Le corpus audio recueilli en 2011 est composé d'entrevues en français et en anglais auprès de locuteurs franco-américains originaires des six états qui composent la Nouvelle-Angleterre. Ce nouveau corpus nous permettra de comparer l'état du français en Louisiane et en Nouvelle-Angleterre et de révéler des caractéristiques similaires.
Three-Dimensional Morphological and Mineralogical Characterization of Testate Amebae
Authors: du Châtelet Eric Armynot , Noiriel Catherine , Delaine Maxence 
Published: September 2013

AbstractTestate amebae are unicellular shelled protozoa commonly used as indicators in ecological and paleoecological studies. We explored the potential application of three-dimensional (3D) X-ray micro-tomography used in addition to 2D techniques (environmental scanning electron microscopy, electron probe micro-analysis, and cathodoluminescence) for detailed characterization of agglutinated shells of protozoa. We analyzed four specimens of the aquatic testate ameba Difflugia oblonga (Arcellinida), to test whether size distribution and mineral composition of shell grains diverged from sediment size distribution and mineralogical composition. From the 3D images, the geometry of the specimens (size and mass) and of the individual grains forming the specimen (grain size distribution and volume) were calculated. Based on combined chemical, mineralogical, and morphological analyses we show that D. oblonga is able to selectively pick up the small size fraction of the sediment with a preference for low-density silicates close to quartz density (~2.65). The maximum size of the grains matches the size of the pseudostome (shell aperture), suggesting the existence of a physical limit to grain size used for building the shell. This study illustrates the potential of this combined approach to characterize agglutinated shells of protozoa. This data can be useful for detailed morphological studies with applications in taxonomy and ecology.
The perception of radiation therapy students on a clinical specialist radiation therapist-led breast workshop
Authors: Lee Grace , Tan Kieng , Dinniwell Robert 
Published: September 2013

AbstractPurposeThe clinical specialist radiation therapist (CSRT) is a radiation therapist with advanced site-specific clinical skills and knowledge that can be utilised to enhance the education of radiation therapy (RT) students within an academic setting. The aim of this study is to assess the students’ perception of the teaching provided by a CSRT within a case-based learning workshop tailored for breast cancer.MethodsA workshop that followed the patient's RT treatment pathway (consultation, CT simulation, treatment planning and delivery) was led by a breast-site CSRT to 16 third-year students. Following completion of the workshop, a 4-point Likert-scale survey was distributed to explore the students’ didactic and clinical experiences and their general perceptions of the CSRT's contribution to their breast-site module education.ResultsThe median didactic experience reported by the students were ‘a lot’ in patient care and ‘some’ in treatment unit and treatment planning. In contrast, the students reported less clinical experience; the median response for patient care and treatment unit experience was ‘a little’ and ‘none’ for treatment planning. All 13 students who responded to the survey agreed that the CSRT enhanced their understanding of the material. The students felt engaged in the CSRT-lecture and perceived it as value added. The majority of the students (92%) indicated the CSRT to be a useful learning resource in their training and education. Additional comments provided by the students noted the utility of the CSRT-led lecture in consolidating their knowledge of the breast cancer treatment planning and delivery and suggest further expansion of this learning format to other disease sites.ConclusionsThird-year RT students commencing their clinical practicum will have had a greater proportion of their learning from didactic teaching as opposed to clinical experience. In transitioning to their final year, the focus of the curriculum shifts to the application of theory into the clinical environment. The students perceived the CSRT to be a useful resource to enhance their understanding of the breast-site module and their feedback supports the instructional quality and effectiveness of the CSRT in this clinical teaching role.
Desmodium genetic resources for improving flavonoid concentrations, oil content and fatty acid compositions
Authors: Morris J. B. , Wang M. L. , Tonnis B. 
Published: September 2013

Several Desmodium species are adapted to the environment of Griffin, Georgia, USA. The determination of flavonoid concentrations, oil content and fatty acid compositions of 25 Desmodium accessions representing five species (D. discolor Vogel, D. incanum (G.Mey.) DC., D. intortum (Mill.) Urb., D. sandwicense E. Mey. and D. tortuosum (Sw.) DC.) would add value to the members of the genus Desmodium for possible use as livestock health supplements. In this study, the seeds of these 25 accessions were evaluated for flavonoid concentrations, oil content and fatty acid compositions using high-performance liquid chromatography, nuclear magnetic resonance and gas chromatography, respectively. Several accessions exhibited significantly greater values for all the traits than the controls. The Desmodium accessions produced significantly greater concentrations of quercetin and kaempferol than the best control accession (D. incanum, PI 477072). However, all the Desmodium accessions produced significantly greater concentrations of isorhamnetin and luteolin than the control accessions. All the Desmodium accessions had greater linoleic (18:2) and behenic (22:0) acid content than a couple of D. incanum control accessions in 2010 and 2011. Significant correlations were observed between several traits. The concentration of quercetin was significantly correlated with that of kaempferol (r2= 0.69***); however, the concentration of quercetin exhibited a significantly negative correlation (r2= − 0.41*) with that of isorhamnetin. Oil content was significantly correlated with palmitic acid (r2= 0.61**), stearic acid (r2= 0.81***), linolenic acid (r2= 0.58**) and lignoceric acid (r2= 0.80***) content. This information will assist breeders and other scientists in developing superior cultivars with optimum levels of flavonoid concentrations, oil content and fatty acid compositions for many of these Desmodium species.
A novel compact microstrip lowpass filter with wide rejection band and sharp transition band using diamond-shaped resonator
Authors: Hayati Mohsen , Amiri Mozhgan , Faramarzi Zahra 
Published: September 2013

In this paper, a novel compact microstrip lowpass filter (LPF) using diamond-shaped resonator with wide rejection and sharp transition band is presented. The proposed filter has −3 dB cut off frequency at 2.6 GHz. The maximum insertion loss is only 0.1 dB in the passband and the rejection band extends from 2.89 to 20.84 GHz with the attenuation level better than −21 dB. The transition band is only 0.288 GHz, from 2.606 to 2.894 GHz with corresponding attenuation levels of −3 and −20 dB, respectively. The filter size is 12.4 × 11.5 mm2. The proposed filter is fabricated and tested, where the measurement results are in good agreement with the simulation results. The proposed LPF has compact size, simple structure, wide rejection band, and low insertion loss, where all of these characteristics are essential for LPF in the modern communication circuits.
Individualisation in crisis planning for people with psychotic disorders
Authors: Farrelly S. , Szmukler G. , Henderson C. , Birchwood M. , Marshall M. , Waheed W. , Finnecy C. , Thornicroft G. 
Published: September 2013

Background.In England, people with a serious mental illness are offered a standardized care plan under the Care Programme Approach (CPA). A crisis plan is a mandatory part of this standard; however, the quality and in particular the level of individualisation of these crisis plans are unknown. In this context, the aim of this study was to assess the quality of crisis planning and the impact of exposure to a specialized crisis planning intervention.Method.The crisis plans of 424 participants were assessed, before and after exposure to the Joint Crisis Plan (JCP) intervention, for ‘individualisation’ (i.e., at least one item of specific and identifiable information about an individual). Associations of individualisation were investigated.Results.A total of 15% of crisis plans were individualised at baseline. There was little or no improvement following exposure to the JCP. Individualised crisis plans were not associated with a history of prior crises or incidences of harm to self and others.Conclusions.Routine crisis planning for individuals with serious mental illness is not influenced by clinical risk profiles. ‘Top down’ implementation of the policy is unlikely to generate the best practice and compliance if clinicians do not perceive the clinical value in the process.
Quantitative analysis of intra-Golgi transport shows intercisternal exchange for all cargo
Authors: Dmitrieff Serge , Rao Madan , Sens Pierre 
Published: September 2013

Significance
Two models compete to explain the way proteins transit through the Golgi, a cellular organelle consisting of stacked membrane-bound compartments (cisternae) and responsible for protein maturation and sorting. The cisternal maturation model proposes that cisternae created de novo move through the stack, carrying their content with them. The vesicular transport model views cisternae as static structures between which proteins are exchanged by vesicular transport. We have developed a transport model that can quantify the importance of intercisternal exchange by analyzing the spatiotemporal evolution of a protein distribution within the Golgi. Intercisternal exchange is confirmed both for small membrane proteins and large protein complexes. This suggests the involvement of membrane carriers much larger than typical protein-coated vesicles.
Simultaneous modeling of visual saliency and value computation improves predictions of economic choice
Authors: Towal R. Blythe , Mormann Milica , Koch Christof 
Published: September 2013

SignificanceMany everyday decisions require viewing displays with several alternatives and then rapidly choosing one, e.g., choosing a snack from a vending machine. Each item has objective visual properties, such as saliency, and subjective properties, such as value. Objective and subjective properties are usually studied independently. We have implemented a single integrated paradigm that links perceptual with economic decision making by having subjects search through visual displays to choose a single food item that they want to eat. We demonstrate that two linked accumulator models, one modeling perceptual and the other modeling economic decisions, account for subjects’ viewing patterns and choices.
Dissection of Cdk1–cyclin complexes in vivo
Authors: Ear Po Hien , Booth Michael J. , Abd-Rabbo Diala , Kowarzyk Moreno Jacqueline , Hall Conrad , Chen Daici , Vogel Jackie , Michnick Stephen W. 
Published: September 2013

Significance
A simple strategy is described to discover cyclin dependency of general cell cycle regulatory kinase cyclin-dependent kinase 1 for substrates in vivo. γ-Tubulin is discovered to be a specific B cyclin Clb3–cyclin-dependent kinase 1 substrate. The strategy can link proteins to specific phases of the cell cycle, and it can be used to determine subunit dependencies for other posttranslational modifying enzymes.
Testicular volume is inversely correlated with nurturing-related brain activity in human fathers
Authors: Mascaro Jennifer S. , Hackett Patrick D. , Rilling James K. 
Published: September 2013

Significance
Life History Theory posits a trade-off between mating and parenting effort, which may explain some of the observed variance in human fathers’ parenting behavior. The current study tested this hypothesis by measuring aspects of reproductive biology related to mating effort, as well as paternal nurturing behavior and the brain activity related to it. Both testosterone levels and testes volume were negatively correlated with paternal caregiving. In response to viewing pictures of one’s own child, brain activity in a key component of the reward and motivation system predicted paternal caregiving and was negatively related to testes volume. These results suggest that the biology of human males reflects a trade-off between mating effort and parenting effort.
Early developmental emergence of human amygdala–prefrontal connectivity after maternal deprivation
Authors: Gee Dylan G. , Gabard-Durnam Laurel J. , Flannery Jessica , Goff Bonnie , Humphreys Kathryn L. , Telzer Eva H. , Hare Todd A. , Bookheimer Susan Y. , Tottenham Nim 
Published: September 2013

Significance
Early adversity has profound and lasting effects on neurodevelopment and emotional behavior. Under typical environmental conditions, prefrontal cortex connections with the amygdala are immature during childhood and become adult-like during adolescence. Rodent models show that maternal deprivation accelerates this development as an ontogenetic adaptation to adversity. Here, we demonstrate that, as in the rodent, children who experienced early maternal deprivation exhibit early emergence of mature amygdala–prefrontal connectivity. Evidence suggests that the adult-like neural phenotype, which is mediated by cortisol levels, confers some degree of enhanced emotion regulation, as maternally deprived youths with adult-like phenotypes are less anxious than their counterparts with immature phenotypes. Accelerated amygdala–prefrontal development may serve as an ontogenetic adaptation in the human in response to early adversity.
Lysine 63-linked polyubiquitination is required for EGF receptor degradation
Authors: Huang Fangtian , Zeng Xuemei , Kim Woong , Balasubramani Manimalha , Fortian Arola , Gygi Steven P. , Yates Nathan A. , Sorkin Alexander 
Published: September 2013

Significance
Many proteins are modified by the covalent attachment of a small polypeptide called ubiquitin to their lysine residues. Lysines in ubiquitin itself are further ubiquitinated, leading to formation of ubiquitin chains. Single ubiquitins and ubiquitin chains attached to integral membrane proteins, such as receptors, transporters, and channels, serve as molecular signals mediating endocytosis of these proteins and their subsequent targeting to lysosomes for degradation. This work uses quantitative mass spectrometry to show that activated EGF receptor is ubiquitinated by one to two short polyubiquitin chains linked via ubiquitin lysine 63 or conjugated with a single monoubiquitin. It is demonstrated that these Lys63-linked polyubiquitin chains are necessary for efficient targeting of EGF receptor to the lysosomal degradation pathway.
A chemostat array enables the spatio-temporal analysis of the yeast proteome
Authors: Dénervaud Nicolas , Becker Johannes , Delgado-Gonzalo Ricard , Damay Pascal , Rajkumar Arun S. , Unser Michael , Shore David , Naef Felix , Maerkl Sebastian J. 
Published: September 2013

Significance
The ability to culture and image microbes on the single-cell level has provided insight into many biological phenomena. Single-cell studies were made possible through the development of microfluidic devices, which have been restricted to culturing a handful of strains at a time. We developed a microfluidic microchemostat array capable of culturing 1,152 yeast strains and demonstrate that the platform is capable of large-scale analysis by imaging the entire yeast-GFP library under numerous environmental conditions. Aside from identifying novel regulatory mechanisms, large-scale single-cell analysis will be useful for cellular engineering.
Watching energy transfer in metalloporphyrin heterodimers using stimulated X-ray Raman spectroscopy
Authors: Biggs Jason D. , Zhang Yu , Healion Daniel , Mukamel Shaul 
Published: September 2013

Significance
Energy transfer in multiporphyrin arrays is of fundamental interest and plays an important role in natural and artificial light harvesting. In this work, we show how ultrafast hard X-ray pulses may be used to create localized electronic wavepackets in a metalloporphyrin dimer. Energy migration between monomers is detected through a stimulated Raman process, resonant with the metal core. Combining the broad bandwidth of attosecond pulses with the localized nature of core orbitals results in a much higher degree of localization and temporal resolution than is possible with optical pulses.
In-fiber production of polymeric particles for biosensing and encapsulation
Authors: Kaufman Joshua J. , Ottman Richard , Tao Guangming , Shabahang Soroush , Banaei Esmaeil-Hooman , Liang Xiangdong , Johnson Steven G. , Fink Yoel , Chakrabarti Ratna , Abouraddy Ayman F. 
Published: September 2013

Significance
A scalable, chemistry-independent, fluid-instability–mediated in-fiber route for fabricating uniformly sized spherical polymeric particles over a wide span of diameters is developed targeting biomedical applications. Both surface functionalization of solid biocompatible polymer particles for protein–protein interactions and volume encapsulation of a biological material in spherical hollow polymer shells are confirmed, in addition to combining both surface and volumetric functionalities in the same polymeric particle.
Acrylamide concentration determines the direction and magnitude of helical membrane protein gel shifts
Authors: Rath Arianna , Cunningham Fiona , Deber Charles M. 
Published: September 2013

Significance
SDS/PAGE is a protein analysis technique universally used in biochemistry, cell biology, immunology, and virology, where proteins are separated by size on a gel matrix of polyacrylamide. However, most helical membrane proteins, which are biomolecules that comprise 20–30% of genomes and the majority of drug targets, migrate to positions on SDS/PAGE that have for decades been unpredictably larger or smaller than their actual size. We have found that the magnitude and direction of migration among membrane protein mimetics are controlled by the acrylamide concentration in the gel. Our results facilitate straightforward SDS/PAGE analysis of these important biomolecules.
Chemically armed mercenary ants protect fungus-farming societies
Authors: Adams Rachelle M. M. , Liberti Joanito , Illum Anders A. , Jones Tappey H. , Nash David R. , Boomsma Jacobus J. 
Published: September 2013

Significance
We document the behavioral interactions among three ant species: a fungus-growing host ant, a permanently associated parasitic guest ant, and a raiding agro-predator ant. We show that the presence of guest ants becomes advantageous when host ants are attacked by raider ants, because guest ants use alkaloid venom to defend their host ant colony. Furthermore, detection of the guest ant odors is sufficient to discourage raider scouts from recruiting nestmates to host colonies. Guest ants likely have evolved this protective behavior because they also perish when their host colony dies.
Decisions on the fly in cellular sensory systems
Authors: Siggia Eric D. , Vergassola Massimo 
Published: September 2013

Significance
Cell-signaling pathways are often presumed to convert just the level of an external stimulus to response. However, in contexts such as the immune system or rapidly developing embryos, cells plausibly have to make rapid decisions based on limited information. Statistical theory defines absolute bounds on the minimum average observation time necessary for decisions subject to a defined error rate. We show that common genetic circuits have the potential to approach the theoretical optimal performance. They operate by accumulating a single chemical species and then applying a threshold. The circuit parameters required for optimal performance can be learned by a simple hill-climbing search. The complex but reversible protein modifications that accompany signaling thus have the potential to perform analog computations.
Efficient water oxidation catalyzed by homogeneous cationic cobalt porphyrins with critical roles for the buffer base
Authors: Wang Dong , Groves John T. 
Published: September 2013

Significance
Efficient and scalable catalysts that mediate the interconversion of electrical and chemical energy are essential to the future world economy. Central to this challenge are robust systems that can split water into its elements, hydrogen and oxygen, with minimal cost. In this article, we describe the discovery and characterization of an efficient, single-site homogeneous water oxidation catalyst based on a cationic cobalt-porphyrin system. Important roles of the buffer base in this catalysis are also described. Our results shed light on the design of next-generation water oxidation catalysts using earth-abundant transition metals and redox active ligand systems.
Finding a 61.0 d orbital period for the HMXB 4U 1036−56 with the Swift-BAT monitoring
Authors: Cusumano G. , Segreto A. , La Parola V. , Masetti N. , D'Aì A. , Tagliaferri G. 
Published: September 2013

Abstract
Since 2004 November, the Burst Alert Telescope on board Swift is producing a monitoring of the entire sky in the 15–150 keV band, recording the timing and spectral behaviour of the detected sources. Here, we study the properties of the High mass X-ray binary (HMXB) 4U 1036−56 using both the BAT survey data and those from a Swift-X-ray Telescope (XRT) observation. A folding analysis performed on the BAT light curve of the first 100 months of survey unveils a periodic modulation with a period of ∼61.0 d, tied to the presence in the BAT light curve of several intensity enhancements lasting ∼1/4 of P0. We explain this modulation as the orbital period of the binary system. The position of 4U 1036−56 on the Corbet diagram, the derived semimajor orbit axis (≃180 R⊙) and the bulk of the source emission observed in a limited portion of the orbit are consistent with a Be companion star. The broad-band 0.2–150 keV spectrum is well modelled with a flat absorbed power law with a cutoff at ∼16 keV. Finally, we explore the possible association of 4U 1036−56 with the γ-ray source AGL J1037−5808, finding that the BAT light curve does not show any correlation with the γ-ray outburst observed in 2012 November.