bluuebunny/crossref_metadata_2025_split huggingface dataset:
Predictors of subacute postoperative pain after total knee arthroplasty: A secondary analysis of two randomized trials
Authors: Springborg Anders H. , Kehlet Henrik , Nielsen Niklas I. , Gromov Kirill , Troelsen Anders , Varnum Claus , Foss Nicolai B. 
Published: July 2024

AbstractBackgroundMethods for identifying high‐pain responders undergoing total knee arthroplasty remain important to improve individualized pain management. This study aimed at evaluating pre‐ and perioperative predictors of pain on Days 2–7 after total knee arthroplasty.MethodsThis is a secondary analysis of data from 227 patients participating in two randomized trials. Pain outcomes were mean pain during walking on Days 2–7 and on Days 2, 4 and 7. Multivariable linear and logistic regressions were carried out in two steps. First, only preoperative available variables including demographics, comorbidities, pain catastrophizing scale and preoperative pain were evaluated while controlling for trial intervention and recruitment site. In the second step, perioperative variables and pain during walking 24 h postoperatively were added.ResultsThe model with only preoperative predictors for mean pain Days 2–7 showed preoperative pain (R‐squared 0.097) as the only predictor. In the second model, adding postoperative available variables, only pain 24 h postoperatively (R‐squared 0.248) was significant, with a significant main effect of recruitment site. Results for the separate day analysis similarly showed preoperative pain and pain during walking 24 h postoperatively as predictors. The overall best sensitivity (60%) and specificity (74%) for predicting a high‐subacute postoperative pain response on Days 2–7 was with cut‐off values of VAS 45.5 (out of 100) for pain during walking 24 h postoperatively.ConclusionsPostoperative pain during walking at 24 h is predictive of subacute postoperative pain on Days 2–7 after total knee arthroplasty, while preoperative pain was only a weak predictor.Significance StatementThis study investigated factors associated with pain after total knee arthroplasty beyond the immediate postoperative period. The analysis revealed significant associations between preoperative pain levels and, particularly, pain 24 h postoperatively, with subsequent subacute pain the following week. These findings can assist in identifying patients who would benefit from enhanced, individualized analgesic interventions to facilitate postoperative recovery.
Ultrasound‐assisted synthesis of biodiesel in the presence of a novel catalyst recovered from waste effluent/water: A mini‐review
Authors: Sai Bharadwaj A. V. S. L. , Ilangovan Athithyan , Kameswari K. Sri Bala , Patle Dipesh Shikchand , Kamsonlian Suantak 
Published: July 2024

AbstractThe government of India has mainly focused on waste management, environment protection acts, and control of energy demand, which will lead to the development of a clean and green India. Nowadays most of the drinking water is getting polluted due to the harmful gases released by well‐renowned industries mining operations, alloy industries, and dye industries. The presence of more amounts of heavy metals in drinking water leads to a rise in chemical levels than the constrained level in the environment, inside a human body, and any living being. Protection of the environment through the recovery of heavy metals from waste effluents through a chemical activation process using bio‐derived activated carbons as adsorbents is one of the known strategies in the current decade that can be adopted. The application of these heavy metals as catalysts in the synthesis of biodiesel from nonedible oils through an ultrasound (US)‐assisted process is one of the emerging strategies that will help in the reduction of energy demand. In the current review, the recovery of heavy metals from the waste effluents through a conventional chemical activation process and their applications as catalysts in the US‐assisted synthesis of biodiesel from nonedible oils is discussed.
Exploring the interplay of renewable energy and carbon dioxide emissions across US sectors through wavelet approach
Authors: Trimech Anyssa 
Published: July 2024

AbstractClimate change presents urgent challenges that require simultaneous attention to environmental and economic dimensions. Addressing this global issue involves tackling its root causes and closely monitoring progress in energy transition efforts to formulate effective strategies. Understanding the complexities and opportunities of shifting toward low‐carbon economies underscores the necessity for innovative sector‐specific policies promoting sustainable energy practices and reducing air pollution. An insightful grasp of how energy transitions impact environmental sustainability is critical, highlighting sector‐specific dynamics for informed policy and decision‐making. This study employs a wavelet approach to explore the relationship between CO2 emissions and renewable energy consumption, analyzing both aggregate and sector‐specific metrics. This time‐varying analysis offers a view of how this relationship evolves over time, providing valuable insights into the effectiveness and outcomes of sustainable energy strategies. Drawing on a dataset spanning from January 1989 to March 2022 in the United States, the research identifies coherence and co‐movements across different frequencies and time dimensions. Results underscore the need to tailor energy strategies to sector‐specific dynamics, particularly noting that despite the growing adoption of renewable energies in industrial and transportation sectors, their impact on reducing CO2 emissions remains limited. However, the electric power sector shows a promising potential for reducing emissions through increased renewable energy integration.
Dietary and lifestyle‐related factors behind delayed conception in females
Authors: Rizvi Maryam Khalid , Rabail Roshina , Munir Seemal , Rizvi Muhammad Waleed , Abdi Gholamreza , Aadil Rana Muhammad 
Published: July 2024

AbstractDelayed conceiving is a failure of a female to attain clinical pregnancy within a year without the use of contraception or any precautionary measure. The females of reproductive age (20–49 years) are the sufferers, that is, about 1.5 million or 10% of couples globally are facing this issue. Delayed conception can be caused by several reasons including diet, lifestyle, and genetic and clinical problems. Deficiencies or overconsumption of any nutrient may also cause delayed conception in females. Dietary deficits such as iron, iodine, zinc, folate, and vitamin D reduce the ovarian reserve. Heavy metals such as copper, manganese, lead, and cadmium also have an impact on fertility. Overconsumption of fast foods and nonhome‐made foods increases the likelihood of infertility by 2–3. Smoking, physical activity, age, polycystic ovary syndrome (PCOS), obesity, and depression have all been considered lifestyle and clinical factors. If women have a sedentary lifestyle, too much exercise or obesity both contribute to infertility. In clinical factors, type 1 diabetes, insulin resistance, and hypertension mainly cause infertility. Our focus in this review is on the studies probe that how these variables contributed to delayed conception and how it can be controlled to help combat infertility. Prevention from delayed conception involves consuming a healthy and balanced diet that contains essential nutrients engaging in physical activity and abstaining from smoking, PCOS, and medical issues.
The effect of synbiotic supplementation on plasma levels of advanced glycation end products and cardiovascular risk factors in hemodialysis patients: A double‐blind clinical trial
Authors: Azamian Yasaman , Abdollahzad Hadi , Rezaeian Shahab , Rouhani Mohammad Hossein , Fatehi Mohammad Hossein 
Published: July 2024

AbstractThere is increasing evidence supporting the relationship between imbalance of gut microbiota and development of chronic kidney and cardiovascular diseases. This study aimed to investigate the effect of synbiotic supplementation on plasma levels of advanced glycation end products (AGEs) and cardiovascular risk factors in hemodialysis (HD) patients. In this randomized, double‐blind, placebo‐controlled clinical trial, 36 HD patients were randomly allocated into two groups to receive two synbiotic supplements (n = 19) or placebo (n = 17) daily for 12 weeks. Levels of AGEs, fibrinogen, hemoglobin A1c (HbA1c), and other measures were assessed at the beginning and end of the study. The data were analyzed using independent t‐tests, paired t‐tests, and analysis of covariance (ANCOVA). At the end of the study, the plasma levels of AGEs increased significantly in both the synbiotic (p < .001) and control (p = .001) groups, but the difference between the groups was not significant (p = .272). Plasma levels of fibrinogen decreased specifically within the synbiotic group (p = .007), and a statistically significant disparity between the groups persisted at the study's conclusion (p = .016). The mean levels of blood urea nitrogen (BUN) decreased (p < .05) in both groups, but there was no difference between the two groups at the end of the study (p = .116). No significant differences were observed in other measured biomarkers. Synbiotic supplementation improved plasma fibrinogen and BUN levels in HD patients, but did not significantly improve AGEs and HbA1c. Further investigations are needed to investigate the effect of probiotics on AGEs in HD patients at different stages of kidney disease.
Expanding the landscape of oncogenic drivers and treatment options in acral and mucosal melanomas by targeted genomic profiling
Authors: Turner Jacqueline A. , Van Gulick Robert J. , Robinson William A. , Mughal Tariq , Tobin Richard P. , MacBeth Morgan L. , Holman Blair , Classon Anthony , Bagby Stacey M. , Yacob Betelehem W. , Hartman Sarah J. , Silverman Ian , Vorwald Victoria M. , Gorden Nicholas , Gonzalez Rita , Gay Laurie M. , Ali Siraj M. , Benson Adam , Miller Vincent A. , Ross Jeffrey S. , Pitts Todd M. , Rioth Matthew J. , Lewis Karl D. , Medina Theresa , McCarter Martin D. , Gonzalez Rene , Couts Kasey L. 
Published: July 2024

AbstractDespite advancements in treating cutaneous melanoma, patients with acral and mucosal (A/M) melanomas still have limited therapeutic options and poor prognoses. We analyzed 156 melanomas (101 cutaneous, 28 acral, and 27 mucosal) using the Foundation One cancer‐gene specific clinical testing platform and identified new, potentially targetable genomic alterations (GAs) in specific anatomic sites of A/M melanomas. Using novel pre‐clinical models of A/M melanoma, we demonstrate that several GAs and corresponding oncogenic pathways associated with cutaneous melanomas are similarly targetable in A/M melanomas. Other alterations, including MYC and CRKL amplifications, were unique to A/M melanomas and susceptible to indirect targeting using the BRD4 inhibitor JQ1 or Src/ABL inhibitor dasatinib, respectively. We further identified new, actionable A/M‐specific alterations, including an inactivating NF2 fusion in a mucosal melanoma responsive to dasatinib in vivo. Our study highlights new molecular differences between cutaneous and A/M melanomas, and across different anatomic sites within A/M, which may change clinical testing and treatment paradigms for these rare melanomas.
Conspectus of the Triticeae
Authors: Löve Áskell 
Published: July 2024

SummaryThis is a taxonomical and nomenclatural survey of the more than 500 biological taxa of the Triticeae tribe of grasses in a system of thirty‐seven genomically defined genera based on twenty‐three single‐haplome taxa as recently validated elsewhere. An analytical key is given. to the genera, which are concisely described and defined; brief information on their genomic constitution is added. When appropriate, subgeneric divisions are described and listed with their synonyms. So are also the accepted names of the biological species and subspecies, with validations of transfers or new names when pertinent; chromosome numbers are added when known, those confirmed by the author with an exclamation mark.
A new nickelphilous species of Alyssum (Cruciferae) from Portugal: Alyssum pintodasilvae T. R. Dudley
Authors: Dudley T. R. 
Published: July 2024

SummaryNickel hyperaccumulation of taxa of Alyssum Section Odontarrhena growing on serpentine substrates has been well documented in recent years by several investigators. One such taxon from Portugal, previously described as A. serpyllifolium subspecies lusitanicum T. R. Dudley & A. R. Pinto da Silva, is A. pintodasilvae T. R. Dudley, sp. nov. This new species is distinguished by demonstrating a maximum nickel‐hyperaccumulating capability of nearly 1.44% tissue concentration on dry weight basis as contrasted to the non‐serpentine A. serpyllifolium Desfontaines which possesses a nickel‐hyperaccumulation potential of no more than 0.0065%. Numerous morphological character discontinuites also support the taxonomic judgement that A. pintodasilvae is bost recognized at full specific rank.
Stomatal classifications — a review
Authors: Inamdar J. A. , Mohan J. S. S. , Subramantan R. Bagavathi 
Published: July 2024

SummaryIn order to avoid confusion terminologies to describe: (i) adult stomatal types; (ii) stomatal ontogeny; (iii) stomatal structure; and (iv) stomatal distribution should be used separately. (i) Thirteen adult stomatal types — anomocytic, anisocytic, actinocytic, diacytic, paracytic, cyclocytic, polocytic, desmocytic, pericytic, tetracytic, hexacytic, hemiparacytic, and staurocytic; (ii) three ontogenetic groups — perigenous, mesogenous and mesoperigenous; (iii) five for stomatal structure — acyclic, bicyclic or diacyclic, tricyclic, tetracyclic and polycyclic and (iv) three for stomatal distribution — epistomatic, hypostomatic and amphistomatic widely used in literature should be accepted. Stomatal meristemoid or stoma mother cell should be replaced by a term “stomatocyte”.
Les grandes unités phytosociologiques au Mali central Première partie: Les milieux humides
Authors: Aberlin Jean‐Pierre 
Published: July 2024

ResuméDe nombreux travaux effectués durant ces 20 dernières années par les agrostologues de l'Institut d'Elevage et de Médeeine Vétérinaire des pays Tropicaux (I. E. M. V. T. — Maisons‐Alfort) ont conduit à définir, en République du Mali, divers groupements végétaux.Un séjour de quatre années eonsécutives (1974 à a 1977) a permis, par traitement informatique des données recueillies, de nommner diverses unités phytosociologiques dans une région du Mali central et ceci dans les milieux secs et humides.Seules les unités se trouvant dans les milieux humides seront présentées dans cet article; elles sont formées par: un Ordre, deux Allianees, deux Sous‐Alliances, et huit Associations.
Revision der mitteleuropäischen tertiären Fagaceen nach blattepidermalen Charakteristiken
Authors: Kvaček Z. , Walther H. 
Published: July 2024

ZusammenfassungDryophyllum Debey ex Saporta wird neu typisiert und als Formgattung für auf Blätter begründete fossile Fagaceen ähnliche Sippen reserviert (Dryophyllum pseudofurcinerve Rüffle et al., D. altenburgense Walther, D, diversinervium Rüffle et al.) Nach weiblichen Infloreszenzen, Kupulen, Früchten und Blattresten wird nach der gemeinsamen epidermalen Struktur die Gattung Eoirigonobalanus Walther & Kvaček gen. nov. aufgestellt (E. andreanszkyi (Mai) Kvaček & Walther comb. nov., E. furcinervis (Rossmässler) Walther & Kvaček comb. nov.). Die Gattung wird von zahlreichen Fundorten Mitteleuropas nachgewiesen. Unterschiede in der Blattmorphologie und Trichomausbildung werden durch die formae E. furcinervis f. haselbachensis (Kvaček & Walther) comb. nov., E. furcinervis f. lyellii (Heer) comb. nov. berücksichtigt. Eotrigonobalanus gen. nov. stellt eine ursprüngliche Fagacee dar, bei der Merkmale von Trigonobalanus Forman, Castanopsis Spach und Lithocarpus Blume kombiniert auftreten. Eotrigonobalanus kommt im subtropischen Lauraceen‐Fagaceen‐Wald vor, ist ein Akzessorium der Mixed‐Mesophytic‐Forests und ist an der Zusammensetzung kohlenbildenden Bruch‐ und Moorwälder gemeinsam mit der Taxodiacee Athroiaxis couttsiae (Heer) Gardner beteiligt.
Occurrence and distribution of certain ergastic substances in some species of Euphorbiaceae in relation to taxonomy and function 1. Tannins
Authors: Okoli B. E. , Erefamote G. M. O. , Nwajagu G. 
Published: July 2024

SummaryThe occurrence and distribution of tannins in 27 species spread over three tribes of Euphorbiaceae were determined histochemically. Only five species : Manihot glaziovii, M. esculenta, Euphorbia hyssopifolia, E. pulcherrima and Ricinodendron heudelotii showed a complete absence of tannins in petiole sections. Other species had tannin containing cells distributed in various tissues and at varying frequencies in the stem and leaves. The results indicate that the family Euphorbiaceae consists of predominantly tannin‐producing species and that tannin‐content or lack of it is of taxonomic importance at the generic and specific levels. The localization of tanniniferous cells mainly in the epidermal cells in many species corroborate the view that the functions of tannins include a protective one.
Persulfate activation enhanced by sulfur‐doped cobaltous tetroxide for rapid and efficient degradation of atrazine
Authors: Liu Shanjun , Sun Shan , Xu Yahui , Zhang Jianlin 
Published: July 2024

AbstractBACKGROUNDAtrazine is present in aquatic systems as a pesticide, and poses a serious threat to ecosystems and human health. The advanced oxidation technology based on persulfate is considered a promising approach for removing trace pesticides from water. The synthesis of a persulfate activator for the rapid and efficient degradation of atrazine was studied.RESULTSA novel rod‐like sulfur‐doped Co3O4 (S‐Co3O4) was prepared via the hard template method and used as a persulfate activator to degrade atrazine. The removal efficiency of atrazine (10 mM) could be up to 100% in the presence of peroxymonosulfate (1 mM) activated by S‐Co3O4 (50 mg L−1) within 7 min.CONCLUSIONThe nanorod structure of S‐Co3O4 is conducive to mass transfer and increases the probability of reaction between substances, and sulfur doping increases the interfacial charge transfer capability. The mechanism of atrazine degradation was mainly attributed to the combined effects of •OH and SO4•−, with the effect of SO4•− being more important. The main degradation pathways of atrazine are dichlorination, hydroxylation and dealkylation, corresponding to the cleavage of Cl1‐C9, N5‐C10 and N6‐C11, respectively. © 2024 Society of Chemical Industry (SCI).
In vivo experimental study comparing alveolar ridge preservation versus guided bone regeneration after unassisted socket healing at intact and damaged sites in narrow alveolar ridges
Authors: Shin Hae Jee , Park Jin‐Young , Tien Hsu Kuo , Strauss Franz‐Josef , Cha Jae‐Kook , Lee Jung‐Seok 
Published: July 2024

AbstractBackgroundTo compare bone regeneration and dimensional alteration of alveolar ridge at intact and damaged extraction sockets after alveolar ridge preservation (ARP) and implant placement versus unassisted socket healing followed by guided bone regeneration (GBR) with simultaneous implant placement.MethodsIn 6 beagle dogs, 3 types of extraction sockets in the mandible were created: (1) intact sockets, (2) 1‐wall defect sockets and (3) 2‐wall defect sockets. The sockets were allocated to undergo either (1) ARP and implant placement 8 weeks later (ARP group) or (2) GBR with simultaneous implant placement after 8 weeks of unassisted socket healing (GBR group). After an additional healing period of 8 weeks, bone regeneration and dimensional changes were evaluated radiographically and histologically.ResultsGBR showed superior bone formation and greater bone gains compared to ARP, regardless of the initial extraction‐socket configuration. Although ARP maintained the preexisting alveolar ridge dimensions, peri‐implant bone defects were still detected at 8 weeks of follow‐up. Histomorphometric analyses confirmed that GBR increased dimensions of the alveolar ridge compared to baseline, and the augmentation and bone regeneration were greater with GBR than with ARP.ConclusionEarly implant placement with ARP can mitigate alveolar ridge changes in the narrow alveolar ridge. However, early implant placement with simultaneous GBR creates the conditions for enhanced bone regeneration around the implant and greater ridge augmentation compared to ARP, irrespective of the extraction‐socket configuration.
Concurrent DNA meta‐barcoding and plankton imaging reveal novel parasitic infection and competition in a diatom
Authors: Catlett Dylan , Peacock Emily E. , Fontaine Diana N. , Taylor Crockford E. , McKenzie Mary J. , Rynearson Tatiana A. , Sosik Heidi M. 
Published: July 2024

AbstractLittle is known about diatom parasitism in marine systems. Guinardia delicatula, a biomass‐dominant diatom on the Northeast US Shelf (NES), is regularly parasitized by the protistan nanoflagellate, Cryothecomonas aestivalis in this region. While G. delicatula is known to host other protistan parasites, direct observation of these interactions and their dynamics in nature remain elusive. Here, we integrate concurrent DNA meta‐barcoding and automated imaging‐in‐flow cytometry observations to characterize the dynamics of G. delicatula infection by a second parasite, Pirsonia (likely Pirsonia verrucosa). In contrast with C. aestivalis infections, Pirsonia infections are observed sporadically and typically only in a small fraction of the G. delicatula population on the NES. An exception was found in February 2020, when an anomalous co‐infection event was observed in G. delicatula featuring > 20% infection prevalence by Pirsonia and > 10% infection prevalence by C. aestivalis. Investigation of each parasite's infection dynamics' relationship with temperature and salinity suggested that C. aestivalis may consistently dominate G. delicatula infection dynamics due to its wider thermal tolerance range and more cosmopolitan distribution. Pirsonia only appeared capable of dominating G. delicatula infection at temperatures near or below 4°C, a known temperature threshold below which C. aestivalis infection is suppressed. Our results demonstrate the utility of integrating DNA meta‐barcoding and plankton imaging to observe the dynamics of diatom–parasite interactions in marine systems and shed light on the diversity of infection dynamics in diatom–parasite systems and the forcings governing competition among diatom parasites for a single host.
Cerebellum in Alzheimer's disease and other neurodegenerative diseases: an emerging research frontier
Authors: Yang Cui , Liu Guangdong , Chen Xi , Le Weidong 
Published: July 2024

AbstractThe cerebellum is crucial for both motor and nonmotor functions. Alzheimer's disease (AD), alongside other dementias such as vascular dementia (VaD), Lewy body dementia (DLB), and frontotemporal dementia (FTD), as well as other neurodegenerative diseases (NDs) like Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS), Huntington's disease (HD), and spinocerebellar ataxias (SCA), are characterized by specific and non‐specific neurodegenerations in central nervous system. Previously, the cerebellum's significance in these conditions was underestimated. However, advancing research has elevated its profile as a critical node in disease pathology. We comprehensively review the existing evidence to elucidate the relationship between cerebellum and the aforementioned diseases. Our findings reveal a growing body of research unequivocally establishing a link between the cerebellum and AD, other forms of dementia, and other NDs, supported by clinical evidence, pathological and biochemical profiles, structural and functional neuroimaging data, and electrophysiological findings. By contrasting cerebellar observations with those from the cerebral cortex and hippocampus, we highlight the cerebellum's distinct role in the disease processes. Furthermore, we also explore the emerging therapeutic potential of targeting cerebellum for the treatment of these diseases. This review underscores the importance of the cerebellum in these diseases, offering new insights into the disease mechanisms and novel therapeutic strategies.