bluuebunny/crossref_metadata_2025_split huggingface dataset:
1615 – Internal Shame: Differences Between Men And Women Greek Roma
Authors: Kotrotsiou S. , Gouva M.I. , Gourgoulianis K. , Paralikas T. , Hatzoglou C. , Skenteris N. 
Published: July 2013

IntroductionInternational and Greek literature on Roma psychological features remains exceptionally limited.ObjectiveThis study examined the internal shame on Greek Roma.AimPresent study evaluated internal shame in a Roma population living in Greece and assess the differentiation of these feelings between Roma men and women.Materials and methods361 individuals (125 male and 236 female with mean age 33.96 SD=12.77), residents of the general area of Greece, participated in the present study. The measuring tools used were: a) the Experience of Shame Scale (ESS), b) a questionnaire concerning socio-demographic information.ResultsThe mean of the internal shame (ESS total) was 39.68 ± 10.67 (men), 49.06 ± 14.20 (women) (p= .000). The mean of the behavioral shame was 18.00 ± 5.61 (men), 20.69 ± 6.12 (women) (p= .000). The analysis of variance between age groups showed that age and Educational level did not affect the internal shame in Greek Roma. Marital status had a significant effect on internal shame of Greek Roma where the application of the Bonferonni criterion found that divorced participants demonstrated a statistical significant difference from those with different marital status (p =.009), the latter had lower levels of internal shame.ConclusionLevels of internal shame in the group of Roma women is very high and higher than Roma men and the influence of marital status on the internal shame is important for Greek Roma.
1625 – External Shame To Greek Roma
Authors: Kotrotsiou S. , Paralikas T. , Gourgoulianis K.I. , Gouva M. , Kotrotsiou E. , Skenteris N. 
Published: July 2013

IntroductionBelonging to a minority often leads to stigmatization and reduction of social power.ObjectiveThe current study assessed the role of external shame on Greek Roma.AimThe present study aimed at evaluating external shame in a Roma living in Greece and assess the differentiation of these feelings between Roma men and women.Materials and methods361 individuals (125 male and 236 female with mean age 33.96 SD=12.77), residents of the general area of Greece, participated in the present study. The measures used were: a) the Other As Shamer scale (OAS) b), a questionnaire concerning sociodemographic information.ResultsThe mean of the external shame (OAS total) was 24,08±13,71 (men), 31,84±15,15 (women) (p= .000). The mean of the inferior was 10,34±5,90 (men), 13,19±6,45 (women) (p= .000). The mean of the empty was 3,85±3,26 (men), 6,19±3,80 (women) (p= .000) and Mistakes was 8,64±5,28 (men), 10,85±5,17 (women) (p= .000). The analysis of variance showed that age did not affect the external shame in Greek Roma. Marital status and educational level had a significant effect on external shame of Greek Roma where the application of the Bonferonni criterion found that unmarried participants demonstrated a statistical significant difference from those married (p =.000), the latter had higher levels of external shame and illiterate participants demonstrated a statistical significant difference from those primary school graduates (p =.000), the latter had higher levels of external shame.ConclusionThe role of gender, educational level and marital status are particularly important to increase the external shame to Greek Roma.
1626 – Feedback Versus Non-feedback To Improve Patient Outcome In Group Psychotherapy For Eating Disorders: a Randomised Clinical Trial
Authors: Davidsen A. , Lau M. , Poulsen S. , Waaddegaard M. 
Published: July 2013

IntroductionOne out of four patients with eating disorders drop out of psychotherapeutic treatment. The high rate of dropout calls for ways to improve treatment adherence. Research indicates that continuous feedback to patient and therapist during treatment reduces the number of dropout and increases outcome; however there are only two published randomised trials on the effect of feedback on the treatment of eating disorders showing inconclusive results, and there are no randomised trials on the effect of feedback in group therapy.ObjectivesWe are investigating the impact of continuous feedback on dropout and outcome in group therapy. The hypothesis is that continuous feedback to patient and therapist on treatment progress and alliance will1)reduce the number of dropouts and2)increase treatment outcome.AimsWe aim to discover if feedback is a way of improving adherence in group therapy for outpatients with eating disorders.MethodsThe trial is set up in a randomised design with 196 outpatients diagnosed with bulimia nervosa, binge eating disorder or eating disorder not otherwise specified, according to the DSM-IV. They are allocated toa)systemic and narrative group therapy with feedback intervention orb)systemic and narrative group therapy as usual.In the experimental group, two sets of feedback measures are added to the treatment as usual: the outcome rating scale and the group session rating scale.Results and conclusionsIf the results will confirm the hypothesis, this trial will support feedback as a way to improve treatment adherence for outpatients with eating disorders.
1631 – Repetitive Transcranial Magnetic Stimulation (rtms) As a New Supportive Tool In The Therapy Of Panic Disorder?
Authors: Deppermann S. , Vennewald N. , Haeussinger F.B. , Sickinger S. , Ehlis A.-C. , Fallgatter A.J. , Zwanzger P. 
Published: July 2013

IntroductionWith a life-time prevalence of about 3.5 percent, Panic disorder (PD) belongs to the most common anxiety disorders which can often chronify if not treated adequately. Characterized by the sudden onset of unexpected panic attacks it is associated with a significant loss of quality of life. As in other anxiety disorders, inadequate top-down regulation of subcortical structures by the prefrontal cortex (PFC) is assumed to be a core feature.Objectives/aimsEven though fMRI studies could show that Cognitive Behavioral Therapy (CBT) is an effective treatment method that can normalize prefrontal hypoactivity, the onset of its effect is delayed. Moreover, recent neuroscientific studies indicated a beneficial effect of repetitive transcranial magnetic stimulation (rTMS), which has been shown to modulate neural activity by depolarization of cortical neurons. The goal of this study was, therefore, to investigate the application of a sham (placebo) controlled activating rTMS protocol during CBT.MethodsForty PD patients were assessed with the optical imaging method near-infrared-spectroscopy (NIRS) while performing emotional paradigms as well as a cognitive task before and after receiving 15 sessions of rTMS.ResultsPreliminary results show a significant increase in prefrontal activation from the beginning to the end of the treatment period. This effect was even larger in the active rTMS group.ConclusionIt can hence be concluded that it is possible to depict the effects of CBT on a neural level after only three weeks. Furthermore, rTMS seems to serve as a useful tool in terms of supporting the general therapy outcome.
1640 – A New Simple Score Of Behavioral & Psychological Symptoms Of Dementia (bpsd)
Authors: Abe K. , Kurata T. , Deguchi K. , Yamashita T. , Ikeda Y. 
Published: July 2013

IntroductionThere are a number of clinical scores to measure cognitive impairment and behavioral and psychological symptoms of dementia (BPSD) for dementia patients.ObjectivePrevious BPSD scores are well established, but they usually take long time. Furthermore they were made almost 20 years ago, and therefore may not even fit a current BPSD because affective expressions may change depending on modern society change.AimTo make a new and simple score which fits modern change of BPSD.MethodBased on BPSD inquiry from 129 caregivers in local area (patients 81.6 ± 9.9 years old and female 70.5%), a new and simple BPSD score was created, and compared to standard BPSD score NPI (neuropsychiatry inventory). Time was measured to complete this new BPSD score (ABS, Abe's BPSD score) and NPI. This ABS was examined before and after a choline esterase inhibitor treatment.ResultWe gave final scores to each BPSD items with such temporal frequencies taken into account ranging 0-9, and finalized a new BPSD score of score 0-44 between no BPSD to full BPSD. Average time to complete both NPI and ABS was 308.9 ± 86.3 sec and 46.5 ± 16.2 sec (**p< 0.01), respectively. Galantamine showed an improvement of average ABS with - 2.3 ± 1.0 (*p< 0.05) from original score of 6.1 ± 6.6 after 3 month of the treatment.ConclusionThese data suggest that this new and simple BPSD score (ABS) may be beneficial to quickly evaluate BPSD before and after a treatment of dementia patients.
1642 – The Association Between Duration Of Untreated Psychosis (dup) And Long-term Outcome In Schizophrenia. a Systematic Review Andmeta-analysis
Authors: Penttilä M. , Hirvonen N. , Isohanni M. , Jääskeläinen E. , Miettunen J. 
Published: July 2013

IntroductionDuration of untreated psychosis (DUP) is one of the few potentially modifiable predictors of outcome in schizophrenia. The long DUP and its relation to poor short-term outcome of schizophrenia has been studied in meta-analyses, but the conclusions remain unclear regarding the long-term effects of DUP.AimTo study the association between DUP and long-term outcome in a meta-analysis.MethodsA systematic literature search of studies on DUP and long-term outcome in schizophrenia was performed using seven electronic databases. Studies were included if the follow-up was at least two years, the majority of subjects had a diagnosis of schizophrenia and DUP was studied with at least one of the following outcome categories: positive, negative, general and total symptoms, need of treatment, social functioning, employment, global outcome, quality of life and remission. Random effect methods were used to pool the effects of original studies.Results2636 unique publications were identified of which 37 met our pre-defined selection criteria. Long DUP correlated with more severe positive (number of studies n=16; r=0.17), negative (n=17; r=0.14), general (n=4; r=0.29) and total symptoms (n=7; r=0.14) and with poor social functioning (n=13; r=0.13), poor global outcome (n=15; r=0.22) and less likely remission (n=16; r=0.14). The association between long DUP and decreased need of treatment was close to statistical significance (n=12; r=0.12). Employment (n=5) and quality of life (n=5) were not associated with DUP.ConclusionSevere symptoms and decreased functionality does not seem to increase the need of treatment or decrease the quality of life or employment.
1643 – Efficacy Of Agomelatine In More Anxious Elderly Depressed Patients. a Randomized, Double-blind Study vs Placebo
Authors: Heun R. , Corral R.M. , Ahokas A. , Nicolini H. , Teixeira J.M. , Dehelean P. 
Published: July 2013

Agomelatine, has been shown to be effective and well-tolerated, in treating: major depressive disorder, anxiety symptoms of depression (1,2) and Generalized Anxiety Disorder (3,4).The present analysis evaluate the antidepressant efficacy of agomelatine in the more anxious elderly depressed patients ≥ 65 years, based on a score of the HAMD combined items 10 and 11 ≥ 5 at baseline.In this 8-week international double-blind randomized study, among 222 elderly depressed out-patients randomized, 119 were more anxious: 82 in the agomelatine 25-50 mg group and 37 in the placebo group.In the total population, the mean HAM-D total score significantly decreased from baseline to endpoint with agomelatine vs placebo, p=0.013.In the more anxious population, the decrease on the mean HAM-D total score was also significantly higher with agomelatine (from 27.8 ± 3.0 to 12.2 ± 7.9) vs placebo (from 28.1 ± 3.3 to 16.3 ± 8.8) with a difference in favor of agomelatine of 4.14 (SE=1.57), p=0.010. The response rate (on HAM-D) was higher on agomelatine (68.3%) than on placebo (40.5%), p=0.004. On the three SDS scores, patients reported significantly less symptom-related impairments on agomelatine than on placebo on work/daily activities (p=0.001), in social life (p=0.020), and in family life (p=0.010).In these patients, most common reported adverse events and more frequent on agomelatine were somnolence, headache, nausea, diarrhoea, upper respiratory tract infection and pain in extremity. There was no transaminases increase.This results show that agomelatine is efficacious in the treatment of more anxious elderly depressed patients.
1644 – Genetic Variability And Heroin Dosage Requirements In Opioid-dependent Individuals
Authors: González D. , Cañadas M. , Aguilera M. , Reyes J.A. , Plaza A. , Calleja M.Á. 
Published: July 2013

IntroductionEffective and safe prescription of individualized opioid-doses for opioid-dependent is a complicated task for the clinician, due inter-individual differences in dosage requirements and narrow therapeutic range.Mu-opioid receptor gene (OPRM1) plays a key role in addiction. A118G-rs1799971 polymorphism in OPRM1 is probably the most promising biomarker of better response in opioid-dependents.Gene polymorphisms in CYP450-isoenzymes (CYP3A5, CYP3A4, CYP2D6, CYP2B6, CYP1A2, CYP2C9 and CYP2C19) also significantly influence pharmacokinetics and effects of opioids and concomitant treatments.Objectives and aimsAssociation of heroin-dose requirements to OPRM1-rs1799971, CYP3A4-rs2740574 and CYP3A5- rs776746 gene polymorphisms in patients from a Heroin Prescription Program (PPH) in Andalusia.MethodsSeries of cases: 15 patients with opioid-addiction. Collection of heroin-doses/patient administered for a year. Genotyping of A118G, CYP3A4 and CYP3A5 polymorphisms was performed by Polymerase Chain Reaction and Restriction Fragment Length Polymorphism.ResultsEleven patients were AA homozygous (11/15;73.33%) and four heterozygous AG (4/15;26.67%) for A118G-OPRM1; median doses: 179.57[157.85,225.49] and 271.38[145.11,288.88]mg/day respectively were no statistically different (p=0.240). Four subjects presented doses>250mg/day, showing an association of AG-OPRM1 genotype with higher doses, OR:30.00(CI95%:1.41,638.15);p=0.033.Fourteen patients were homozygous AA and GG for CYP3A4 and CYP3A5 respectively (14/15;93.33%), and one patient was heterozygous AG(1/15;6.66%) for both isoenzymes and presented a high dose(280 mg/day).ConclusionsHigher heroin-doses (>250mg/day) were associated to AG genotype for OPRM1-A118G, despite the great variability in the dose prescription avoided to find an association between OPRM1 genotype and the specific administered dose.Pharmacogenetic analysis, focused on OPRM1-A118G, may be a useful tool to adjust the pharmacotherapeutic dose in each case.
1646 – Genetic Risk Factors For Interferon-induced Anxiety
Authors: Udina M. , Moreno-España J. , Navinés R. , Langohr K. , Gratacós M. , Forns X. , Capuron L. , Vieta E. , Solà R. , Martín-Santos R. 
Published: July 2013

Background/aimsInterferon-alpha (IFN-α) and Ribavirin is the recommended treatment for chronic hepatitis C (CHC). Common treatment side-effects include neuropsychiatric symptoms such as anxiety, which impairs patient's quality of life and treatment adherence. Inflammation and neurotransmission systems may play a role in the pathogenesis of IFN-α-induced anxiety. The GC/GG genotype at a polymorphism located in the interleukin-6 synthesizer gene (IL6 gene) has been related with a higher production of IL-6 and “higher inflammation response”. A polymorphism in the serotonin transporter gene (SERT) has been related with anxiety and antidepressant response. The aim of the study was to assess the role of IL6 and SERT polymorphisms as predictive variables of IFN- induced anxiety.Material/methodsA cohort of 385 Caucasian outpatients with CHC initiating antiviral treatment. Patients were euthymic and without current anxiety disorder (SCID) at baseline. Anxiety evaluation: Hospital anxiety and depression scale. Assesment: Baseline, 4, 12, 24, and 48 weeks after antiviral treatment initiation. DNA was extracted and polymorphisms genotyped. Hardy- Weinberg equilibrium: IL-6 (p=0.72) and SERT (p=0.41). Statistical analysis: linear mixed-effects.ResultsPatients carrying the G allele (GC/GG genotype) of IL6 polymorphism (G vs. CC) had more anxiety symptoms (p=0.004) during antiviral treatment. We did not find a significant effect of SERT (S vs. LL) on anxiety (p=0.15). No significant interaction between both genes was reported.ConclusionGC/GG genotype, that implies higher seric concentrations of IL6, predicts interferon-α-induced anxiety supporting a role of inflammatory pathway on pathophysiology of anxiety.GrantsPSICOCIT-VHC-P110/01827, and PSIGEN-VHC-EC08/00201. ERDF, European Union “One way to make Europe”.
1652 – Child Pornographers: Clinical Features Of a Virtual Assault
Authors: Prat S. , Bertsch I. , Jonas C. 
Published: July 2013

IntroductionThe child pornography collecting process and the way the pornographer considers his collection need to be better understood. It is these psychopathological issues and the risk of the person acting out his fantasies that need to be analyzed.ObjectivesWe want to understand the phenomenon of child pornography, because it is sometimes a matter of deviance without leading to actual abuse.AimsThe aim of our study is thus to identify the characteristics of people who download child pornography.MethodsWe collected datas from forensic psychiatric assessments. The criterion for inclusion was the possession of pornographic images of minors. We studied pathological characteristics of this sample.ResultsSubjects were almost exclusively male with an average age of forty years. They have generally a good academic level. A significant difference is observed between the childhood aspects of child pornographers, sex online and offline offenders. A sense of loneliness is expressed in 32.8%.ConclusionChild generally fulfills a fantasy of a pedophile nature. Different profiles of child pornographers have been proposed which are not always related to pedophilia. Our study has permitted to have informations about the sexuality of child pornographers. The feel to not be well integrated could explain the use of virtual mean of telecommunication. Clinical differences can be made between child pornographers and sex online offenders.
1659 – The Development Of a Case Formulation Training Package For Probation Staff
Authors: Brown S. , Hedges L. , Patel G. , Duggan C. , Vollm B. 
Published: July 2013

IntroductionA recent UK Government initiative has sought to address the management of personality disordered (PD) offenders, aiming to improve public protection by reducing reoffending whilst simultaneously improving the psychological health of offenders with PD. Case formulation (CF) is given primacy here as it enhances offender management through a psychologically informed approach and informs pathway planning through Criminal Justice System or NHS services. Probation services are given an important role in formulating cases as part of the new strategy.ObjectivesDevelop a consensus amongst professionals as to what makes a good Case Formulation (CF). Investigate whether probation services can be taught CF skills, and to enhance these skills.AimsDevelop a case formulation training package for probation staff and evaluate the training.MethodThe training package was informed by the results of a Delphi survey amongst professionals, and focus groups with probation staff, offenders and carers of individuals with PD.ResultsThere was consensus that CF allows for collaboration between client and therapist, helps with complexity through organisation of case notes and has utility in treatment planning. Themes highlighted for effective CF included background, trauma, offending, risk and current lifestyle. The theoretical model gaining most support was a CBT model. The assessment of formulations was identified as challenging.The CF training package is currently being evaluated and findings will be presented at the conference, alongside outcomes of all phases of the research.ConclusionsCF has the potential to enhance treatment planning. Its suitability for probation staff will be discussed.
1665 – Gender Differences In Depressive Co-morbidity And Suicidal Behaviour Among Delusional Disorder Patients
Authors: González-Rodríguez A. , Molina-Andreu O. , Imaz Gurrutxaga M.L. , Bernardo Arroyo M. , Catalán Campos R. 
Published: July 2013

IntroductionAlthough gender differences in schizophrenia are well known, this topic in delusional disorder (DD) has been poorly studied. Previous studies have shown an earlier mean age at onset in men than in women, and in those with depressive co-morbidity.ObjectivesTo examine demographic and clinical differences by gender in DD.AimsTo compare depressive co-morbidity and suicidality between men and women.MethodsNinety-seven patients with delusional disorder (DSM-IV-RT), attended at the Department of Psychiatry (Hospital Clinic-BCN) from 2000 to 2012, were included and followed up for one year. Demographic and clinical features at index admission, pharmacological treatment, compliance, presence of depressive co-morbidity and suicidal behaviour at follow-up were recorded. For comparisons, T, Chi-square tests and analysis of covariance (ANCOVA) were used.ResultsSeventy-six per cent were women and the most common delusional idea was delusion of persecution (74.2%). Gender differences regarding demographic features and depressive co-morbidity were not found. 22.7% of the sample presented suicidal ideation and 12.4% attempted suicide during follow-up. Women became ill later than men (50.07 vs.44.57 years), but when ANCOVA model is used with age at onset as dependent variable, sex as factor, and depressive co-morbidity and suicidal behaviour as covariates, this difference was not significant for sex effect. Women attempted suicide more often than men (13.5% vs. 8.7%) and showed less compliance during the evaluation period.ConclusionsNo gender differences in age at onset, types of DD, presence of depression and severity of global functioning were found. Women showed higher suicidal behaviour.
1666 – The Burden Of Accelerated Ageing In Schizophrenia
Authors: Cohen D. , Nugter A. 
Published: July 2013

IntroductionAmong patients with schizophrenia there is a significant increased prevalence of type 2 diabetes mellitus. In addition, schizophrenia is accompanied by 15–32 years reduced life-expectancy. We hypothesize a contribution from accelerated ageing.ObjectivesTo compare Autofluorescence (AF) levels of patients with severe mental illness (SMI) with the general population.AimsTo test to what extent accelerated ageing is specific for patients with schizophrenia.MethodOutpatients with SMI were asked to participate. AF levels were measured with the AGE-reader. Patients with diabetic mellitus were excluded from the analyses.Results[Mean AF values in study-population (N=122)]Age-cohortsGeneral PopulationSMI-populationt-valueSize Study Population20–29 years1.532.175.95***N=1130–39 years1.732.2110.20***N=3040–49 years1.812.317.85***N=4350–59 years2.092.857.03***N=2460–69 years2.462.8252.44*N=14*p< .05***p< .001Of the 154 patients who were asked to participate 70,8% were male, 74,3% suffered from schizophrenia, 15,3% from diabetes mellitus and of 3% the skin was too dark for a reliable assessment. Only 5 patients refused to participate.A regression analysis with age as single predictor, confirmed the predictive value of age. Compared to the general population (R2 = .60), the explained variance of R2=.23, p< .001 in the study population is low. Addition of duration of treatment or psychiatric diagnosis as predictors did not change the outcome.ConclusionAF-values indicate that accelerated ageing is present in patients with SMI.