bluuebunny/crossref_metadata_2025_split huggingface dataset:
Epidemiology of Field of Vision Disorders (eFOVID) study, Western Australia, 1988–2022. Report 1: Data collection and aggregation protocol
Authors: Manners Siobhan , Morgan William , Morlet Nigel , Meuleners Lynn , Liu Wei , Morlet Hector , Ng Jonathon Q. 
Published: July 2024

AbstractBackgroundComputerised static visual field testing using dedicated machines such as the Humphrey Field Analyzer (HFA) can assess and track changes in visual field sensitivity. The use of retrospective visual field databases is a novel undertaking, with no studies published utilising large scale population‐level data. This study phase developed a method to extract HFA data into a large standardised population‐based database including point sensitivity data with additional derived variables.MethodsRetrospective, longitudinal, population study of visual field data from people who attended an ophthalmology service and had a HFA field test, in Western Australia, between 1988 and 2022. Raw test data included patient demographic fields, sensitivity readings and test parameters. Calculated fields included reliability scores, and a novel combined reliability score.ResultsThere were 606 230 tests for 92 215 study individuals, from 22 ophthalmology practices in metropolitan Perth and three public hospital eye clinics, representing around 85% of the field tests performed by ophthalmologists each year. Raw sensitivity values were available for all tests, and additional descriptors were available for most tests (97.5%–100% of tests) with the exception of data variables retired by the manufacturer.ConclusionsVisual field data from 606 230 tests were collated into a single dataset, which is highly representative over a long period of time, for a defined population. This dataset has been linked to other administrative datasets to allow for epidemiological investigation of field of vision disorders.
‘Crossed the line’: Sexuality discourses of motherhood under 15 years in Uganda
Authors: Kamusiime Annah 
Published: July 2024

AbstractMotherhood under 15 years is constructed as having crossed the line of societal morals and this construction shapes the provision of sexual and reproductive health services (SRH) for mothers under 15 years in Uganda. Using collaborative ethnography and through the lens of discourses and governmentality, I established that adolescent pregnancy is constructed within normative discourses enshrouded in religious and cultural values. What is constructed as non‐normative is regulated through restrictive SRH policies and penalizing discourses which inhibit access to SRH services and care. A paradigm shift in adolescent SRH policies that are rooted in human rights and equity is one alternative required.
Swimming capacity and behaviour of juvenile round goby (Neogobius melanostomus)
Authors: Chow Eddie , Zarini Sina , Coffield Olivia , Chippindale Quinn , Balshine Sigal 
Published: July 2024

AbstractThe round goby (Neogobius melanostomus) is an example of an invasive species where the adults are unimpressive swimmers and yet via human activities, they have managed to rapidly invade the Laurentian Great Lakes, the Baltic Sea and many rivers in Western Europe. The secondary spread from human‐impacted sites has been attributed to adult life stages, despite their poor swimming capacity. However, the swimming capacity of early life stages of round goby has not been considered before. We therefore quantified critical swimming performance (Ucrit), sprint swimming performance (Usprint), burst swimming speeds and swimming behaviours in early juvenile round goby that ranged between 10 and 25 mm in body length. The average Ucrit, Usprint and burst speeds of these fish were an impressive 0.22, 0.34 and 0.67 m/s respectively, with the capacity of these early juveniles ranging between 41 and 79% of what has been documented for adults. Notably, fish spent more time actively swimming as current speed increased, while station holding decreased. Taken together, our findings highlight that despite their small size, early juvenile round goby are not simply passively moved by currents but have movement capacities that approach that of the much larger adults. Our study emphasizes the need to consider the swimming capacity of all life stages as this information will better predict dispersal and range expansion and will help to design mitigation efforts to potentially prevent the spread of this and other invasive species.
Banking on railroads: The effect of market access on banking provision during the Gilded Age
Authors: Chan Jeff 
Published: July 2024

AbstractI examine the effect that market access, induced by the railroad network expansion, had on banking provision in nineteenth‐century America. I find that market access increased the number of national banks. This effect operated via the extensive margin, with market access increasing the probability of having a national bank for affected counties. I find that counties had more national bank activity, with increased assets, loans, deposits, and other outcomes. I do not, however, find any effect of market access on banks already in operation. Market access therefore increased banking provision chiefly through the increased entry of national banks.
A methodological synthesis of narrative inquiry research in applied linguistics: What's the story?
Authors: Ghanbar Hessameddin , Cinaglia Carlo , Randez Robert A. , De Costa Peter I. 
Published: July 2024

AbstractNarrative inquiry has gained traction in applied linguistics as a complementary approach to positivistic research, focusing on the subjectivities of individuals’ lived experiences and using stories as data, analytical tools, and reporting practice. Although numerous methodologically oriented publications on narrative inquiry in the field reflect its vitality, scholars have raised questions about the complexity and ambiguity underlying what exactly constitutes narrative inquiry. While methodological diversity within narrative inquiry can signal innovation, it can also create uncertainty for novice and experienced scholars engaging with the methodology for the first time. To address these concerns, we conducted a systematic methodological synthesis of narrative inquiry studies in applied linguistics published from 2012 to 2022. Specifically, we searched 12 top‐tier applied linguistics journals and developed a corpus of 291 articles. We coded our corpus according to four areas: (a) theoretical framing, (b) demographic characteristics, (c) methodological design, and (d) reporting of ethics, researcher positionality, and funding status. We discuss our results in light of previous thematic reviews of narrative inquiry in applied linguistics, and we offer empirically grounded recommendations for scholars engaging with narrative inquiry. Our study responds to calls for greater methodological transparency in applied linguistics in general and methodological investment in narrative inquiry in particular.
A global perspective on the treatment and maintenance of mature skin using gentle cleansers and moisturizers
Authors: Fluhr Joachim W. , Alexis Andrew F. , Andriessen Anneke , Ferero Barrios Olga L. , Bjerring Peter , Foley Peter , Gold Michael H. , Kaderbhai Hashim , Zhang Chengfeng 
Published: July 2024

AbstractXerosis is highly prevalent in the population aged over 50 years and substantially impacts quality of life due to the associated stigma, related pruritus, and potential sequelae. We propose that the term mature xerosis be used for subjects over 50 who suffer from age‐related xerosis and replace senile xerosis to describe the phenomenon. The etiology of xerosis depends on genetic and environmental factors that affect stratum corneum hydration and skin barrier function. Skincare to restore barrier function is essential in xerosis treatment and is relevant for maintaining and preventing its progression. Many moisturizers and cleansers are available for xerosis; however, they are underutilized by patients with mature xerosis. A panel of eight global dermatologists reviewed the unique aspects of xerosis in mature skin and discussed the specific needs, relevance, and considerations for skincare selection to prevent, treat, and maintain skin with mature xerosis. The panel selected five statements based on evidence from a literature review and the panel's clinical experience to provide clinical considerations and recommendations for dermatologists and other healthcare providers treating patients with mature xerosis. Increased recognition of the burden of xerosis in mature skin is warranted. Gentle cleansers and barrier‐restoring ceramide‐containing moisturizers are essential to xerosis management, reducing signs and symptoms of xerosis, including associated pruritus.
Co‐constructing cooperative value ecosystems: A critical realist perspective
Authors: Zhang Jun , Zamani Efpraxia D. , Gerli Paolo , Mora Luca 
Published: July 2024

AbstractThis study focuses on digital platform cooperatives (DPCs) and investigates how social value is created within platform cooperativism for fostering a more equitable and inclusive digital landscape. We explore and theorise the outcomes of social value creation by DPCs and identify the generative mechanisms that drive their emergence. We do this by adopting a Critical Realism philosophical stance, in combination with Grounded Theory techniques based on the Straussian version of coding. Our data is drawn from 36 interviews with DPC (co‐)founders, members, and experts, alongside an array of documentary data from DPCs across 12 European countries. Our analysis reveals three outcomes of social value creation by DPCs: strengthening community capacities, federating cooperative ventures, and fostering practices for narrative co‐creation. Additionally, we identify two generative mechanisms with enduring properties and explanatory power: collective identity and empowerment, and government‐community symbiosis. These mechanisms are identified through retroductive theorising, offering plausible explanations for the outcomes of social value creation, situated within relevant contextual conditions, such as grassroots mobilisation and advocacy, institutional commitment and policy support, and legislative frameworks for cooperative integration. This study contributes to the understanding of social value creation in platform cooperativism as an endeavour to co‐construct a cooperative value ecosystem, providing valuable insights for both theory and practice.
The muscle pump activator device: From evidence to lived experiences
Authors: Sibbald R. Gary , Geng Ryan S. Q. , Slomovic Jacqueline , Stacey Michael 
Published: July 2024

AbstractA chronic wound is one that fails to progress through a normal timely sequence of repair, or in which the repair process fails to restore anatomic and functional integrity after 3 months. The most common chronic wounds include venous, ischaemic and mixed leg ulcers, diabetic foot ulcers and pressure injuries. Chronic wounds place immense physical and psychosocial burden on patients and exact heavy costs for healthcare systems, with many patients continuing to live with chronic wounds even after all management options have been exhausted. The muscle pump activator (MPA) device can be used to bridge this therapeutic gap. By stimulating the common peroneal nerve to activate venous muscle pump of the leg and foot, the MPA device increases blood flow to the lower leg and foot to improve conditions for healing. Currently, evidence in the literature exist to show that the MPA device improves wound outcomes over standard compression therapy, decreases edema and increases wound healing rates. In this review, we also present a series of chronic wound patients treated with the MPA device in multicentre clinics to demonstrate the ability of the MPA device to improve wound outcomes, reduce pain and edema and improve patient quality of life.
Hypomagnesaemia, an independent risk factor for the development of post‐transplant diabetes mellitus in liver and renal transplant recipients? A systematic review
Authors: Chen Shujie , Bowen David Geoffrey , Liu Ken , Vidot Helen 
Published: July 2024

AbstractBackgroundPost‐transplantation diabetes mellitus (PTDM) is common after solid organ transplantation. In the past decade, there has been increasing interest in the association between hypomagnesaemia and the development of PTDM. This systematic review aimed to investigate the current knowledge regarding the association between hypomagnesaemia and PTDM in adult liver and renal transplant recipients.MethodsA literature search of five databases, Medline, Embase, ProQuest, Scopus and Google Scholar, as well as article reference lists, was performed. Eligible studies that focused on adult liver and renal transplant recipients without pretransplantation hyperglycaemia or diabetes were included. Other eligibility criteria included quantitative studies which reported magnesium concentrations, studies with at least 6 months of follow‐up, and studies published in English. The Newcastle–Ottawa Assessment Tool was used for the quality assessment.ResultsIn total, 12 studies were included in the final analysis. Eleven focused on renal transplantation and one on liver transplantation. All studies were medium to high quality with eight out of 12 achieving the highest rating of nine. Eight studies found a negative association between either pretransplant or early post‐transplant serum magnesium concentration and the risk of PTDM, three studies found no association between these two variables, and one study found a positive association between the magnesium concentration at 8 weeks after transplantation and glycosylated haemoglobin A1C.ConclusionsFurther large‐scale prospective studies with at least 6 months of follow‐up are needed to confirm these findings, particularly in liver transplantation, to further clarify and explore the relationship between hypomagnesaemia and PTDM.
Designing circular economy strategies in distributed generation for small‐ and medium‐sized enterprises using Monte Carlo simulation
Authors: González‐Domínguez Jaime , Sánchez‐Barroso Gonzalo , Zamora‐Polo Francisco , García‐Sanz‐Calcedo Justo 
Published: July 2024

AbstractThe circular economy (CE) strategies in energy communities enable firms to efficiently manage the excess of photovoltaic energy they produce, and thereby enhance their sustainability. Thus, the present research aims to compare the economic and financial profitability and greenhouse gas (GHG) emissions of shared photovoltaic self‐consumption versus individual self‐consumption in the region of Extremadura (Spain). Six firms with complementary energy profiles were selected, analyzing their hourly energy consumption. In addition, the Monte Carlo method was used to generate 30,000 simulations, reducing the uncertainty caused by the variability of the firms' energy consumption. The results show that collective generation covers the energy needs more efficiently, reducing the cost of energy consumed by 14.38% and generating better cost–benefit ratio. They also show that the CE strategy of the energy community allows firms to obtain a considerable reduction of GHG emissions associated with the photovoltaic energy consumed.
Mapping the global mass flow of seaweed: Cultivation to industry application
Authors: Janke Liam 
Published: July 2024

AbstractThe global flows of cultivated seaweed were estimated for the year 2019 using a combination of literature review, assumptions, and simple conservation of mass calculations. Red seaweeds were found to be the largest contributors to the hydrocolloids industry, for both food and non‐food applications. Carrageenan‐containing species were found to be the largest contributors to both food (62%) and non‐food (55%) hydrocolloids and are the primary source for water gels, which make up 27% of non‐food hydrocolloids, followed by pet food (16%), toothpaste (6%), and others (6%). Carrageenan also accounts for almost all meat products, which make up 35% of the food hydrocolloid industry, and dairy products, which make up 26%. Agar‐containing seaweeds are used in confections (10% of food hydrocolloids), baking (9%), and other (2%) and make up 15% of non‐food hydrocolloids. Porphyra (nori) is cultivated for direct consumption and makes up 23% of direct food consumption. Cultivated brown seaweeds were found to comprise Laminaria/Saccharina for alginate production (30%), Laminaria/Saccharina for direct consumption (44%), and Undaria for direct consumption (16%). About half of the alginates produced make up 18% of food hydrocolloids, and the other half is used in non‐food hydrocolloids comprising technical grades (28% of non‐food) and animal feed (3%). The results are discussed in the context of emerging markets for seaweed and the potential for seaweeds as a substitute for staple foods, and the environmental impact of seaweed farming is explored through a review of life cycle assessment studies.
A common variant in the iron regulatory gene (Hfe) alters the metabolic and transcriptional landscape in brain regions vulnerable to neurodegeneration
Authors: Marshall Moscon Savannah , Neely Elizabeth , Proctor Elizabeth , Connor James 
Published: July 2024

AbstractThe role of iron dyshomeostasis in neurodegenerative disease has implicated the involvement of genes that regulate brain iron. The homeostatic iron regulatory gene (HFE) has been at the forefront of these studies given the role of the H63D variant (H67D in mice) in increasing brain iron load. Despite iron's role in oxidative stress production, H67D mice have shown robust protection against neurotoxins and improved recovery from intracerebral hemorrhage. Previous data support the notion that H67D mice adapt to the increased brain iron concentrations and hence develop a neuroprotective environment. This adaptation is particularly evident in the lumbar spinal cord (LSC) and ventral midbrain (VM), both relevant to neurodegeneration. We studied C57BL6/129 mice with homozygous H67D compared to WT HFE. Immunohistochemistry was used to analyze dopaminergic (in the VM) and motor (in the LSC) neuron population maturation in the first 3 months. Immunoblotting was used to measure protein carbonyl content and the expression of oxidative phosphorylation complexes. Seahorse assay was used to analyze metabolism of mitochondria isolated from the LSC and VM. Finally, a Nanostring transcriptomic analysis of genes relevant to neurodegeneration within these regions was performed. Compared to WT mice, we found no difference in the viability of motor neurons in the LSC, but the dopaminergic neurons in H67D mice experienced significant decline before 3 months of age. Both regions in H67D mice had alterations in oxidative phosphorylation complex expression indicative of stress adaptation. Mitochondria from both regions of H67D mice demonstrated metabolic differences compared to WT. Transcriptional differences in these regions of H67D mice were related to cell structure and adhesion as well as cell signaling. Overall, we found that the LSC and VM undergo significant and distinct metabolic and transcriptional changes in adaptation to iron‐related stress induced by the H67D HFE gene variant.image
Effects of endotracheal suctioning duration cerebral oxygenation in preterm infants
Authors: Merter Ozlem Selime , Dertli Semiha , Taskin Erdal , Aydin Mustafa , Benli Samet 
Published: July 2024

AbstractAimThis study evaluates the effects of endotracheal suctioning duration on cerebral oxygenation and physiological parameters in preterm infants in intensive care.DesignProspective and observational study.MethodIn this study, 51 preterm infants born at 28–34 weeks of gestation in NICU were evaluated. Cerebral oxygenation was measured before, during, and after endotracheal suctioning with near‐infrared spectroscopy. Pain levels of the infants were with N‐PASS scale.ResultsA negative correlation was found between the lowest cerebral oxygenation value during endotracheal suctioning and the duration of endotracheal suctioning. Cerebral oxygenation levels during endotracheal suctioning were lower than pre‐ and post‐endotracheal suctioning levels. Higher cerebral oxygenation was observed in infants whose endotracheal aspiration time was less than 13 s. The duration of endotracheal suctioning was positively correlated with pain and cerebral oxygenation stabilization time.ConclusionProlonged endotracheal suctioning duration negatively affects cerebral oxygenation in preterm infants. The study suggests an optimal endotracheal suctioning duration under 13 s.Implications for the Profession and/or Patient CareProperly executed endotracheal suctioning, with the correct technique and knowledge, can alleviate the adverse physiological effects observed in preterm infants and contribute to routine nursing care in intensive care units.Reporting MethodThis study has been reported in line with STROBE checklists.Patient or Public ContributionNo patient or public contribution was required to design or undertake this research. Patients contributed only to the data collection.ImpactThis study contributes to defining the ideal endotracheal aspiration duration, as there is not enough data so far. It showed the effect of prolonged endotracheal aspiration time on cerebral oxygenation, pain and physiological parameters in preterm infants.
SARS‐CoV‐2 spike protein acts as a β‐adrenergic receptor agonist: A potential mechanism for cardiac sequelae of long COVID
Authors: Deng Xiangning , Cui Hongtu , Liang Hao , Wang Xinyu , Yu Haiyi , Wang Jingjia , Wang Wenyao , Liu Dongyang , Zhang Youyi , Dong Erdan , Tang Yida , Xiao Han 
Published: July 2024

AbstractBackgroundCurrently, pathophysiological mechanisms of post‐acute sequelae of coronavirus disease‐19‐cardiovascular syndrome (PASC‐CVS) remain unknown.Methods and resultsPatients with PASC‐CVS exhibited significantly higher circulating levels of severe acute respiratory syndrome‐coronavirus‐2 spike protein S1 than the non‐PASC‐CVS patients and healthy controls. Moreover, individuals with high plasma spike protein S1 concentrations exhibited elevated heart rates and normalized low frequency, suggesting cardiac β‐adrenergic receptor (β‐AR) hyperactivity. Microscale thermophoresis (MST) assay revealed that the spike protein bound to β1‐ and β2‐AR, but not to D1‐dopamine receptor. These interactions were blocked by β1‐ and β2‐AR blockers. Molecular docking and MST assay of β‐AR mutants revealed that the spike protein interacted with the extracellular loop 2 of both β‐ARs. In cardiomyocytes, spike protein dose‐dependently increased the cyclic adenosine monophosphate production with or without epinephrine, indicating its allosteric effects on β‐ARs.ConclusionSevere acute respiratory syndrome‐coronavirus‐2 spike proteins act as an allosteric β‐AR agonist, leading to cardiac β‐AR hyperactivity, thus contributing to PASC‐CVS.