bluuebunny/crossref_metadata_2025_split huggingface dataset:
Closed Genome Sequence of Octadecabacter temperatus SB1, the First Mesophilic Species of the Genus
Octadecabacter
Authors: Voget Sonja , Billerbeck Sara , Simon Meinhard , Daniel Rolf 
Published: September 2015

ABSTRACT

The Gram-negative alphaproteobacterium
Octadecabacter temperatus
SB1 (DSM 26878) belongs to the marine
Roseobacter
clade. The genome of this strain is the smallest closed genome of the
Roseobacter
clade.
O. temperatus
SB1 is the first described nonpolar mesophilic isolate of the genus
Octadecabacter
and the type strain of the species.
Complete Genome Sequences of Three Neisseria gonorrhoeae Laboratory Reference Strains, Determined Using PacBio Single-Molecule Real-Time Technology
Authors: Abrams A. Jeanine , Trees David L. , Nicholas Robert A. 
Published: September 2015

ABSTRACT

Neisseria gonorrhoeae
, the etiological agent that causes the sexually transmitted infection gonorrhea, is a significant public health concern due to the emergence of antimicrobial resistance. We report the complete genome sequences of three reference isolates with varied antimicrobial susceptibility that will aid in elucidating the genetic mechanisms that confer resistance.
Draft Genome Sequence of a
vanA
-Type Vancomycin-Resistant Reference Strain, Enterococcus faecium ATCC 51559
Authors: Sung Kidon , Khan Saeed , Marasa Bernard , Min Seonggi , Kweon Ohgew , Mohamed Nawaz , Cerniglia Carl 
Published: September 2015

ABSTRACT

Vancomycin-resistant
Enterococcus faecium
has emerged as a multidrug-resistant pathogen in hospital settings. Here, we present the draft genome sequence of a high-level vancomycin-resistant strain,
E. faecium
ATCC 51559, which is employed as a standard laboratory
vanA
genotype-positive control strain for clinical and laboratory studies.
Geographic and socioeconomic variation of sodium and potassium intake in Italy: results from the MINISAL-GIRCSI programme
Authors: Cappuccio Francesco P , Ji Chen , Donfrancesco Chiara , Palmieri Luigi , Ippolito Renato , Vanuzzo Diego , Giampaoli Simona , Strazzullo Pasquale 
Published: September 2015

ObjectivesTo assess geographic and socioeconomic gradients in sodium and potassium intake in Italy.SettingCross-sectional survey in Italy.Participants3857 men and women, aged 39–79 years, randomly sampled in 20 regions (as part of a National cardiovascular survey of 8714 men and women).Primary outcome measuresParticipants’ dietary sodium and potassium intakes were measured by 24 h urinary sodium and potassium excretions. 2 indicators measured socioeconomic status: education and occupation. Bayesian geoadditive models were used to assess spatial and socioeconomic patterns of sodium and potassium intakes accounting for sociodemographic, anthropometric and behavioural confounders.ResultsThere was a significant north-south pattern of sodium excretion in Italy. Participants living in southern Italy (eg, Calabria, Basilicata and Puglia >180 mmol/24 h) had a significantly higher sodium excretion than elsewhere (eg, Val d'Aosta and Trentino-Alto Adige <140 mmol/24 h; p<0.001). There was a linear association between occupation and sodium excretion (p<0.001). When compared with occupation I (top managerial), occupations III and IV had a 6.5% higher sodium excretion (coefficients: 0.054 (90% credible levels 0.014, 0.093) and 0.064 (0.024, 0.104), respectively). A similar relationship was found between educational attainment and sodium excretion (p<0.0001). When compared with those with a university degree, participants with primary and junior school education had a 5.9% higher urinary sodium (coefficients: 0.074 (0.031, 0.116) and 0.038 (0.001, 0.075), respectively). The socioeconomic gradient explained the spatial variation. Potassium excretion was higher in central regions and in some southern regions. Those in occupation V (low-skill workers) showed a 3% lower potassium excretion compared with those in occupation I. However, the socioeconomic gradient only partially explained the spatial variation.ConclusionsSalt intake in Italy is significantly higher in less advantaged social groups. This gradient is independent of confounders and explains the geographical variation.
Use and abuse of medication during 2014 FIFA World Cup Brazil: a retrospective survey
Authors: Vaso Martin , Weber Alexis , Tscholl Philippe M , Junge Astrid , Dvorak Jiri 
Published: September 2015

ObjectiveTo examine the use of medication of top-level male players during the 2014 FIFA World Cup Brazil.DesignRetrospective survey.Participants/information736 top level players.SettingThe teams’ physicians disclosed a list of the medications used by each player within 72 h before each match of the 2014 FIFA World Cup Brazil.Outcome measuresAverage number of medications used per player per match or during the tournament; average number and percentage of players using at least one medication per match or during the tournament.Results67.0% of all players took various types of medication during the tournament. The most used medications during the tournament were non-steroidal anti-inflammatory drugs (NSAIDs), by 54.2% of all players, followed by analgaesics (12.6%); β-2 agonists were only used by 0.5%. On average, 0.8 medications per player were used before each match. More players were reported taking medications during the knockout round than during the qualification round (0.36±0.48 vs 0.49±0.50, p<0.001). Players from the South American and Asian Confederations took twice as many medications per match as players from the African Confederation (1.17±1.55 and 1.01±1.26 vs 0.48±0.69, both p<0.001).ConclusionsThere was high use of NSAIDs during the 2014 FIFA World Cup. Although the intake of NSAIDs per match (0.35±0.46 vs 0.31±0.48, p<0.01) in the 2014 FIFA World Cup decreased compared to the 2010 FIFA World Cup, the average use was still higher than in the 2006 FIFA World Cup, and the average number of all used medications per player remained the same level as 4 years prior, with all its implications for the player's health. More efforts need to be undertaken worldwide in order to reduce the administration of medications in sports, through continuous education for players, starting from a young age, as well as for doctors and paramedics.
Simple interventions can greatly improve clinical documentation: a quality improvement project of record keeping on the surgical wards at a district general hospital
Authors: Glen Peter , Earl Naomi , Gooding Felix , Lucas Emily , Sangha Nicole , Ramcharitar Steve 
Published: September 2015

AbstractClinical documentation is an integral part of the healthcare professional’s job. Good record keeping is essential for patient care, accurate recording of consultations and for effective communication within the multidisciplinary team. Within the surgical department at the Great Western Hospital, Swindon, the case notes were deemed to be bulky and cumbersome, inhibiting effective record keeping, potentially putting patients’ at risk. The aim of this quality improvement project was therefore to improve the standard of documentation, the labelling of notes and the overall filing.A baseline audit was firstly undertaken assessing the notes within the busiest surgical ward. A number of variables were assessed, but notably, only 12% (4/33) of the case notes were found to be without loose pages. Furthermore, less than half of the pages with entries written within the last 72 hours contained adequate patient identifiers on them. When assessing these entries further, the designation of the writer was only recorded in one third (11/33) of the cases, whilst the printed name of the writer was only recorded in 65% (21/33) of the entries.This project ran over a 10 month period, using a plan, do study, act methodology. Initial focus was on simple education. Afterwards, single admission folders were introduced, to contain only information required for that admission, in an attempt to streamline the notes and ease the filing. This saw a global improvement across all data subsets, with a sustained improvement of over 80% compliance seen. An educational poster was also created and displayed in clinical areas, to remind users to label their notes with patient identifying stickers. This saw a 4-fold increase (16%-68%) in the labelling of notes.In conclusion, simple, cost effective measures in streamlining medical notes, improves the quality of documentation, facilitates the filing and ultimately improves patient care.
Identification of Novel Ezrin Inhibitors Targeting Metastatic Osteosarcoma by Screening Open Access Malaria Box
Authors: Çelik Haydar , Hong Sung-Hyeok , Colón-López Daisy D. , Han Jenny , Kont Yasemin Saygideger , Minas Tsion Z. , Swift Matthew , Paige Mikell , Glasgow Eric , Toretsky Jeffrey A. , Bosch Jürgen , Üren Aykut 
Published: September 2015

Abstract
Ezrin is a member of the ERM (ezrin, radixin, moesin) family of proteins and functions as a linker between the plasma membrane and the actin cytoskeleton. Ezrin is a key driver of tumor progression and metastatic spread of osteosarcoma. We discovered a quinoline-based small molecule, NSC305787, that directly binds to ezrin and inhibits its functions in promoting invasive phenotype. NSC305787 possesses a very close structural similarity to commonly used quinoline-containing antimalarial drugs. On the basis of this similarity and of recent findings that ezrin has a likely role in the pathogenesis of malaria infection, we screened antimalarial compounds in an attempt to identify novel ezrin inhibitors with better efficacy and drug properties. Screening of Medicines for Malaria Venture (MMV) Malaria Box compounds for their ability to bind to recombinant ezrin protein yielded 12 primary hits with high selective binding activity. The specificity of the hits on ezrin function was confirmed by inhibition of the ezrin-mediated cell motility of osteosarcoma cells. Compounds were further tested for phenocopying the morphologic defects associated with ezrin suppression in zebrafish embryos as well as for inhibiting the lung metastasis of high ezrin-expressing osteosarcoma cells. The compound MMV667492 exhibited potent anti-ezrin activity in all biologic assays and had better physicochemical properties for drug-likeness than NSC305787. The drug-like compounds MMV020549 and MMV666069 also showed promising activities in functional assays. Thus, our study suggests further evaluation of antimalarial compounds as a novel class of antimetastatic agents for the treatment of metastatic osteosarcoma. Mol Cancer Ther; 14(11); 2497–507. ©2015 AACR.
O Vestido em Panorama: sobre a formação e a relativização de um cânone da historiografia teatral brasileira
Authors: Buarque de Gusmão Henrique , Herzog Thiago 
Published: September 2015

<div class="page" title="Page 2"><div class="layoutArea"><div class="column"><p><span>Este artigo propõe um exercício de história intelectual, buscando encontrar no livro </span><span>Panorama do teatro brasileiro</span><span>, de Sábato Magaldi, algumas chaves explicativas para a criação de um “marco fundador” do teatro brasileiro moderno que se difundiu tão amplamente no ambiente intelectual dos estudos teatrais: a estreia de </span><span>Vestido de noiva</span><span>, de Nelson Rodrigues, em 1943. Para tal, serão analisadas as principais referências que orientam a reflexão de Sábato, assim como os dispositivos centrais que ele constrói para a sua escrita da história do teatro brasileiro. No final do texto, é feita uma reflexão a respeito dos desafios que os historiadores do teatro enfrentam diante do surgimento de novas perspectivas teóricas que desestabilizam as noções de “cânone” e as grandes narrativas que abarcam longos períodos históricos. </span></p></div></div></div>
Fernanda Montenegro em O mambembe: o quelque chose da diva moderna
Authors: Guenzburger Gustavo 
Published: September 2015

<div class="page" title="Page 2"><div class="layoutArea"><div class="column"><p><span>Este trabalho é um estudo sobre a atuação de Fernanda Montenegro no papel de Laudelina na famosa montagem de </span><span>O mambembe </span><span>de 1959, a partir de fotos, testemunhos, críticas e, principalmente, do áudio completo do espetáculo. A discussão sobre a versatilidade da atriz naquele papel pretende se conectar a uma reflexão sobre aspectos determinantes na história da atuação carioca como um todo. No momento da invenção da simbiose entre o teatro e a televisão no Rio de Janeiro, um novo e moderno “divismo” é apontado aqui como resultado de uma versatilidade artística que permitiu, a toda uma geração, negociar seu papel na interseção entre o teatro e a indústria cultural. </span></p></div></div></div>
Legado de Caim: a jornada brasileira do Living Theatre (1970-71)
Authors: Vannucci Alessandra 
Published: September 2015

<div class="page" title="Page 2"><div class="layoutArea"><div class="column"><p><span>Na trajetória do Living Theatre, companhia teatral de origem norte-americana, desde 1964 nômade por opção, a viagem ao Brasil de 1970 a 1971 proporcionou, por meio de experiências extremas de opressão – como a detenção –, a descoberta de novas táticas de ativismo estético-político. Focando um processo teatral que não aconteceu como espetáculo, mas provocou uma espetacular auto exposição dos dispositivos de repressão do regime militar, o artigo se propõe analisar estruturas constitutivas daquela fase da história da nação. </span></p></div></div></div>
Histórias globais do teatro: novas perspectivas para a historiografia
Authors: Junqueira Christine 
Published: September 2015

<div class="page" title="Page 2"><div class="layoutArea"><div class="column"><p><span>As histórias globais do teatro configuram um novo campo de investigação de caráter historiográfico, que vem se delineando com a história do teatro, produzindo novas perspectivas multidisciplinares baseadas no fenômeno da globalização. As relações de criação, produção e distribuição do teatro enquanto commodity, a atuação das redes teatrais internacionais (turnês) são alguns dos temas que interpretam as oportunidades transnacionais de se maximizar o valor do teatro enquanto mercadoria, assim como a mobilidade de artistas, companhias e empresários a partir de meados do século </span><span>XIX</span><span>. </span></p></div></div></div>
Da tela ao palco: pintura, teatro e revolução no Brutus de Jacques-Louis David
Authors: Dessoldi Flavia Giovana 
Published: September 2015

<div class="page" title="Page 2"><div class="layoutArea"><div class="column"><p><span>O artigo discute a contribuição da Revolução Francesa para o campo das artes, mais especificamente para o campo das artes cênicas: a importância do teatro nesse período e o legado deixado após a influência da revolução na ligação entre as linguagens artísticas, analisada a partir da relação entre o quadro </span><em>Brutus</em><span>, de Jacques-Louis David, a montagem da peça de mesmo nome em 1790 escrita por Voltaire, a nova concepção teatral que será desenvolvida e a trajetória de Talma, um ator da Comédie Française que será consagrado a partir de sua posição política assumida durante a Revolução. Também analisa o teatro como ferramenta de protesto e de mobilização das massas. </span></p></div></div></div>
Espaço do Grupo Opinião: vozes dissonantes sobre seu fechamento no Jornal do Brasil
Authors: Calixto Marques Maria Do Socorro 
Published: September 2015

<div class="page" title="Page 2"><div class="layoutArea"><div class="column"><p><span>Neste artigo proponho abordar a publicação no </span><span>Jornal do Brasil</span><span>, em 1980, sobre o fechamento do espaço teatral Opinião. Para analisar o material selecionado, utilizo algumas categorias teóricas sobre discurso e espaço, a exemplo de utopia, heterotopia e formação discursiva, apresentadas por Michel Foucault e Michel de Certeau no tocante a espaços construídos através de narrativas. As duas orientações teóricas apontam para a construção de um lugar como configuração de posições. </span></p></div></div></div>
Espelho falso: a paródia na formação do teatro brasileiro
Authors: Metzler Marta 
Published: September 2015

<div class="page" title="Page 2"><div class="layoutArea"><div class="column"><p><span>Este trabalho articula-se em torno da relação entre as formas paródicas e a atividade teatral desenvolvida no Brasil, com a ideia de que a práxis parodística está diretamente implicada no processo de formação dos autores e na própria construção da noção de </span><span>teatro brasileiro</span><span>. A paródia é uma arte que se manifesta por polifonia, entrecruzando vozes, tempos, lugares, descentrando valores e sentidos artístico-culturais. Considerando que, no caso brasileiro, formas marginais como a paródia ocupam o centro da formação teatral, o olhar se situa nos </span><span>deslimites </span><span>em que se entrelaçam origem e destino, centro e periferia. Objetiva-se realizar um estudo crítico, seguindo uma perspectiva histórica, trabalhando com investigação, registro e análise de material dramatúrgico, bibliográfico e jornalístico, em interconexão com o exame teórico-conceitual fundamentado em estudos contemporâneos da paródia, da história do teatro brasileiro e da cultura. </span></p></div></div></div>
Evasive behaviours of female dusky dolphins (Lagenorhynchus obscurus) during exploitative scramble competition
Authors: Orbach Dara N. , Packard Jane M. , Kirchner Theresa , Würsig Bernd 
Published: September 2015

When males engage in scramble competition, are females non-evasive recipients of male coercion or evasive? Small groups of male dusky dolphins (Lagenorhynchus obscurus) engage in exploitative (non-interference) scramble competition for access to oestrous females near Kaikoura, New Zealand. We conducted behavioural sequence analyses of videos of 48 mating groups with continuous records and focal individual follows of females. We determined (1) the frequency and type of behaviours (non-evasive vs. evasive), (2) the variation in simple transition probabilities of behaviours leading to a copulatory position associated with female resistance and non-resistance and (3) the variation in female responses to male behaviours throughout focal follows. Females exhibited frequent active evasive manoeuvers following male behaviours. Copulation sequences were highly variable and most complex when terminated by females. Females altered responses to male signals, one aspect of mate choice potentially favouring male endurance.
Latronema whataitai sp. n. (Nematoda: Selachinematidae) from intertidal sediments of New Zealand, with notes on relationships within the family based on preliminary 18S and D2-D3 phylogenetic analyses
Authors: Leduc Daniel , Zhao Zeng 
Published: September 2015

Latronema whataitaisp. n. is described from intertidal sediments of Hataitai Beach, North Island of New Zealand, and its placement within the Selachinematidae investigated using 18S and D2-D3 molecular sequences.Latronema whataitaisp. n. is characterised by relatively slender body (a = 22-25), outer labial setae and cephalic setae of similar length, anterior buccal cavity with three sets of seven teeth with larger central tooth positioned above the other six, circular amphid with faint outline, males with 12-13 precloacal supplements and spicules with pointed projection near distal end, and tail 2.0-2.6 anal body diam. long. The cuticle ultrastructure of the genus is investigated for the first time using scanning electron microscopy. Molecular phylogenies of near full length small subunit and D2-D3 expansion segments of the large subunit rRNA genes do not provide support for the division of Selachinematidae into the subfamilies Selachinematinae and Choniolaiminae, and do not support a close relationship betweenLatronemaandRichtersiadespite some morphological similarities. These preliminary results are based on a small number of molecular sequences, and therefore the current morphology-based classification remains the most tractable system for the Selachinematidae until more comprehensive analyses are conducted.
Double Reasoning in the Codified Mixed Systems – Code and Case Law as Simultaneous Methods
Authors: Valentine Palmer Vernon 
Published: September 2015

The thesis of this Article is that the mixed jurisdiction judges often use a system of double reasoning to decide cases under the Civil Codes. In select areas where the Code texts contain principles (rather than rules) and hence are particularly wide, the judges of the codified systems are prone to use two methods at once.This Article describes the judicial use of both syllogistic and inductive reasoning and proposes a new functional classification of civilian jurisprudence. A small case study is used to provide data, concepts and illustrations. The data set encompasses about thirty decisions in the field of medical liability in Quebec, Puerto Rico, and Louisiana. The field of tort law, presided over by the tort General Clause, thus serves as an area par excellence to observe this phenomenon.
Liability of the State and Public Authorities in Israel and South Africa
Authors: Loubser Max , Gidron Tamar 
Published: September 2015

Both the Israeli and the South African legal systems are classified as mixed legal systems, or mixed jurisdictions. In Israel, tort law was originally pure English common law, adopted by legislation and later developed judicially. In South Africa, the law of delict (tort) was originally Roman-Dutch but was later strongly influenced by the English common law. Under both systems, tort law is characterized by open-ended norms allowing extensive judicial development. This paper traces and compares the structural basis, methodology, policy, and trends of the judicial development of state and public-authority liability in the Israeli and South African jurisdictions. Specific factors that have impacted the development of state- and public-authority liability are: (1) constitutional values, (2) the courts’ recognition of the need for expanded protection of fundamental human rights and activism towards achieving such protection, (3) the multicultural nature of the societies, (4) problems of crime and security, and (5) worldwide trends, linked to consumerism, toward the widening of liability of the state and public authorities.Within essentially similar conceptual structures the South African courts have been much more conservative in their approach to state liability for pure economic loss than their Israeli counterparts. This can perhaps be attributed to a sense of priorities. In a developing country with huge disparities in wealth, the courts would naturally be inclined to prioritize safety and security of persons above pure economic loss. The South African courts have been similarly more conservative in cases involving administrative negligence and evidential loss.The development of the law on state and public-authority liability in Israel and South Africa is also the product of factors such as the levels of education, the effectiveness of the public service, and the history and pervasiveness of constitutional ordering. Despite important differences, the law in the two jurisdictions has developed from a broadly similar mixed background; the courts have adopted broadly similar methods and reasoning; and the outcomes show broadly similar trends.