bluuebunny/crossref_metadata_2025_split huggingface dataset:
Idiopathic sterile inflammation of the epidural fat and epaxial muscles causing paraplegia in a mixed-breed dog
Authors: Cornelis Ine , De Decker Steven , Gielen Ingrid , Gadeyne Caroline , Chiers Koen , Vandenabeele Sophie , Kromhout Kaatje , Van Ham Luc M. L. 
Published: May 2013

Abstract
Case Description—A 4-year-old sexually intact male mixed-breed dog was evaluated because of clinical signs of acute-onset pelvic limb ataxia, rapidly progressing to paraplegia with severe spinal hyperesthesia.
Clinical Findings—General physical examination revealed pyrexia, tachycardia, and tachypnea. Neurologic examination demonstrated severe spinal hyperesthesia and paraplegia with decreased nociception. Magnetic resonance imaging revealed extradural spinal cord compression at T13-L1 and hyperintense lesions on T1- and T2-weighted images in the epaxial musculature and epidural space.
Treatment and Outcome—Decompressive surgery, consisting of a continuous dorsal laminectomy, with copious lavage of the vertebral canal was performed. Cultures of blood, urine, and surgical site samples were negative. Histologic examination results for samples obtained during surgery demonstrated suppurative myositis and steatitis. These findings confirmed a diagnosis of sterile idiopathic inflammation of the epidural fat and epaxial muscles with spinal cord compression. The dog's neurologic status started to improve 1 week after surgery. After surgery, the dog received supportive care including antimicrobials and NSAIDs. The dog was ambulatory 1 month after surgery and was fully ambulatory despite signs of mild bilateral pelvic limb ataxia 3 years after surgery.
Clinical Relevance—Although idiopathic sterile inflammation of adipose tissue, referred to as panniculitis, more commonly affects subcutaneous tissue, its presence in the vertebral canal is rare. Specific MRI findings described in this report may help in reaching a presumptive diagnosis of this neurologic disorder. A definitive diagnosis and successful long-term outcome in affected patients can be achieved by decompressive surgery and histologic examination of surgical biopsy samples.
Endoparasitoses of fallow deer (Dama dama) in game-park in South Moravia (Czech Republic)
Authors: Borkovcová M. , Langrová I. , Totková A. 
Published: May 2013

Abstract
During the years 2002–2008 endoparasitoses of fallow deer Dama dama were monitored in White Carpathians (Czech Republic). Samples of excrements were tested by flotation and Baermann method and occasionally grallochs were dissected in order to detect gastrointestinal nematods (GIN) and lungworms (LW). In the same time we cooperated with gamekeepers, who carried out several differently successful measurements to lower the endoparasites’ prevalence. These measurements included pasture management, shooting management, additional-feeding management and drug treatment, all during the whole period of monitoring. Prevalence of endoparasites had descending trend, while intensity of infection had ascending trend. Total maximal prevalence (GIN+LW) in herd was 60 % (2004), in 2008, it fell down to 20 %. Annual dynamic of parasites was always highest in autumn months. Spectrum of detected parasites consisted only of species of the order Strongylida. Monitoring proved, that breeding management strategy can significantly influence parasitocenoses and help animals to regain health.
Small rodents — permanent reservoirs of toxocarosis in different habitats of Slovakia
Authors: Reiterová K. , Antolová D. , Zaleśny G. , Stanko M. , Špilovská S. , Mošanský L. 
Published: May 2013

Abstract
The study aimed to estimate the role of small rodents in the circulation of larval toxocarosis in light of their different habitats. From 2005 to 2008, a total of 1523 small rodents, belonging to 11 species, were captured in 5 different habitats of Slovakia. Anti-Toxocara antibodies were detected in 6.6 % animals. The dominant reservoirs of toxocarosis were striped-field mouse Apodemus agrarius (11.7 %) and mound-building mouse Mus spicilegus (10.7 %), while the seropositivity of voles was low. Sexually active adults were infected more frequently (10.8%) in comparison with inactive ones (5.2 %). According to habitats, seroprevalence of toxocarosis in windbreaks (2.4 %) was significantly lower (p < 0.05) than in agrocoenoses (6.7 %), alluvia (8.5 %) and ecotones (7.5 %). Log-linear analysis performed in A. agrarius indicates that type of habitat and sexual activity affect the seropositivity to Toxocara infection. The highest seroprevalence was observed in alluvium (21.2 %) while the lowest in windbreak (1.8 %) (χ2 = 17.232, p < 0.001) and sexually active mice were characterised by 22.5 % and sexually inactive by 6.4 % seroprevalence (χ2 = 30.634, p < 0.001). The occurrence pattern of toxocarosis in small rodents suggests that they are permanent reservoirs for Toxocara spp. in nature and significant indicators of Toxocara egg contamination in environs.
Microtrema barusi gen. n. and sp. n. (Digenea: Phaneropsolidae) from Prunella modularis (Aves, Passeriformes) in the Czech Republic
Authors: Sitko J. 
Published: May 2013

Abstract
Microtrema gen. n. and Microtrema barusi sp. n. are described from the intestine of Prunella modularis in the Czech Republic. Genus and species have the following features: Body claviform, widest in region of ventral sucker. Tegument densely covered with tiny spines. Suckers small, widely separated. Oral sucker globular, subterminal. Ventral sucker globular, equatorial. Prepharynx very short or absent. Pharynx small, fine. Oesophagus divided into two short intestinal branches ending blindly anterior to testes. Testes globular, lateral, in region of ventral sucker. Vesicula seminalis small, genital pore in short distance before ventral sucker and opening of uterus. Bursa cirri and cirrus absent. Ovary globular, median, between testes. Mehlis’ gland long oval, posterior to ovary. Vitellarium weakly developed, in two lateral clusters composed of small follicles. Uterus in posterior part of body, with many eggs, covering vitellarium and partly ventral sucker. Excretory vesicle V-shaped, pore terminal.
Venolymphatic Malformation of the Proximal Gastrocnemius Muscle in a Girl
Authors: Skabelund Jeremy , Andrews Robert S. 
Published: May 2013

The patient was an 8-year-old girl who was referred to a physical therapist by her pediatrician for a chief complaint of worsening proximal right calf pain and progressive right-sided toe walking for the past 6 weeks. Due to concern that the patient's symptoms were nonmusculoskeletal in nature, the physical therapist discussed the history and physical examination findings with the patient's pediatrician and an orthopaedic surgeon. Subsequent magnetic resonance imaging and percutaneous biopsy led to a diagnosis of a low-flow venolymphatic malformation of the proximal gastrocnemius muscle. J Orthop Sports Phys Ther 2013;43(5):349. doi:10.2519/jospt.2013.0408
Exploring a Practice-Based Approach to Foreign Language Teacher Preparation: A Work in Progress
Authors: Troyan Francis J. , Davin Kristin J. , Donato Richard 
Published: May 2013

Abstract:This article describes the implementation of a practice-based approach to foreign language (FL) teacher preparation. After briefly framing the discussion in relation to the literature on the practice-based approach in teacher education – including Phase I of the American Council on the Teaching of Foreign Languages (ACTFL) Research Priorities – we present the implementation and integration of this approach in the context of FL teacher preparation. The successes and challenges encountered throughout the implementation experience are discussed, and recommendations are made for practice-based course design in FL teacher preparation programs and for future research on the practice-based approach.
Private Edge Domination Number of a Graph
Authors: S Kavitha , C. S Robinson 
Published: May 2013

A set is said to be a private edge dominating set, if it is an edge dominating set, for every has at least one external private neighbor in . Let and denote the minimum and maximum cardinalities, respectively, of a private edge dominating sets in a graph . In this paper we characterize connected graph for which ? q/2 and the graph for some upper bounds. The private edge domination numbers of several classes of graphs are determined.Keywords: Edge domination; Perfect domination; Private domination; Edge irredundant sets.© 2013 JSR Publications. ISSN: 2070-0237 (Print); 2070-0245 (Online). All rights reserved.doi: http://dx.doi.org/10.3329/jsr.v5i2.12024 J. Sci. Res. 5 (2), 283-294 (2013)
Ni-Cu-Zn Ferrite Research: A Brief Review
Authors: Huq M. F. , Saha D. K. , Ahmed R. , Mahmood Z. H. 
Published: May 2013

The temperature at which the ferrite is sintered critically depends on the chemical composition. The electromagnetic properties are dependent on the densification and microstructure. Substitutions and addition of sintering aids is an attractive approach to enhance the electromagnetic properties. Various compositions in the system Ni1-x-yCuxZnyFe2O4 were investigated. Cu is used to decrease the sintering temperature. However, Cu decreases the resistivity, which is not desirable for its high frequency applications. So, optimization of Cu content is necessary. Different ranges of electromagnetic properties have been reported with various Zn concentrations. Optimization of Zn concentration with respect to Ni and Cu is essential to achieve desirable electromagnetic properties. Influence of rare earths has also been reported. The investigations showed an improved densification in Ni-Zn and increased permeability in Cu-Zn ferrite by Sm substitution. La substitutions showed an improved resistivity in Ni-Zn ferrites. Similarly, these substitutions may improve the electromagnetic properties in Ni-Cu-Zn ferrites. V2O5, MoO3 and Bi2O3 were reported to be the most widely used sintering additives. Bi2O3-WO3 and V2O5-MoO3 mixed additives were better than the individual additives in Ni-Cu-Zn ferrite, respectively. Further research is needed on the mixed sintering additivesKeywords: Additives; Ferrite preparation; Ni-Cu-Zn ferrite; Rare Earth; Sintering aids.© 2013 JSR Publications. ISSN: 2070-0237 (Print); 2070-0245 (Online). All rights reserved.doi: http://dx.doi.org/10.3329/jsr.v5i2.12434 J. Sci. Res. 5 (2), 215-233 (2013)
Study of GPS derived Total Electron Content and Scintillation Index variations over Indian Arctic and Antarctic stations
Authors: Bhawre P. , Gwal A. K. , Mansoori A. A. , Khan P. A. 
Published: May 2013

In the present study we have investigated the monthly and seasonal variability of total electron content (TEC) and amplitude scintillation index (S4) over two Indian polar stations Maitri (Antarctic) and Ny-Alesund (Arctic), during the low solar activity period 2008. We have used the Novatels dual frequency GPS receiver GSV4004A to accomplish this study. From our analysis we observed that TEC achieves its highest values during the months of November and December while during the month of May and June the lowest values of TEC were recorded at Maitri station. Similarly during summer season the highest values of TEC are recorded while in winter season lowest values of TEC are observed. The scintillations that occurred during the year 2008 at Maitri as well as at Ny-Alesund were generally found to be of weak type (S4?0.1), although few cases of moderate (S4?0.3) and strong (S4?0.5) scintillation were also observed. The occurrence characteristics of scintillations showed that maximum scintillations at Maitri occur during the month of July and August while least scintillations occur during the month of January and February. This type of ionospheric variability can be explained on the basis of solar irradiance at Polar Regions.Keywords: Total electron content; Scintillation index; Polar ionosphere.© 2013 JSR Publications. ISSN: 2070-0237 (Print); 2070-0245 (Online). All rights reserved.doi: http://dx.doi.org/10.3329/jsr.v5i2.12724 J. Sci. Res. 5 (2), 255-264 (2013)
Effect of Collaborative Care on Cost Variation in an Intensive Care Unit
Authors: Garland Allan 
Published: May 2013

Background
Improving the cost-effectiveness of health care requires an understanding of the genesis of health care costs and in particular the sources of cost variation. Little is known about how multiple physicians, caring collaboratively for patients, contribute to costs.

Objective
To explore the effect of collaborative care by physicians on variation in discretionary costs in an intensive care unit (ICU) by determining the contributions of the attending intensivists and ICU fellows.

Methods
Prospective, observational study using a multivariable model of median discretionary costs for the first day in the ICU, adjusting for confounding variables. Analysis included 3514 patients who spent more than 2 hours in the ICU on the initial day. Impact of the physicians was assessed via variables representing the specific intensivist and ICU fellow responsible on the first ICU day and allowing for interaction terms.

Results
On the initial day, patients spent a median of 10.6 hours (interquartile range, 6.3–16.5) in the ICU, with median discretionary costs of $1343 (interquartile range, $788–2208). There was large variation in adjusted costs attributable to both the intensivists ($359; 95% CI, $244–$474) and the fellows ($756; 95% CI, $550–$965). The interaction terms were not significant (P = .12–.79).

Conclusions
In an ICU care model with intensivists and subspecialty fellows, both types of physicians contributed significantly to the observed variation in discretionary costs. However, even in the presence of a hierarchical arrangement of clinical responsibilities, the influences on costs of the 2 types of physicians were independent.
Rapid Response Teams: Qualitative Analysis of Their Effectiveness
Authors: Leach Linda Searle , Mayo Ann M. 
Published: May 2013

Background
Multidisciplinary rapid response teams focus on patients’ emergent needs and manage critical situations to prevent avoidable deaths. Although research has focused primarily on outcomes, studies of the actual team effectiveness within the teams from multiple perspectives have been limited.

Objective
To describe effectiveness of rapid response teams in a large teaching hospital in California that had been using such teams for 5 years.

Methods
The grounded-theory method was used to discover if substantive theory might emerge from interview and/or observational data. Purposeful sampling was used to conduct in-person semistructured interviews with 17 key informants. Convenience sampling was used for the 9 observed events that involved a rapid response team. Analysis involved use of a concept or indicator model to generate empirical results from the data. Data were coded, compared, and contrasted, and, when appropriate, relationships between concepts were formed.

Results
Dimensions of effective team performance included the concepts of organizational culture, team structure, expertise, communication, and teamwork.

Conclusions
Professionals involved reported that rapid response teams functioned well in managing patients at risk or in crisis; however, unique challenges were identified. Teams were loosely coupled because of the inconsistency of team members from day to day. Team members had little opportunity to develop relationships or team skills. The need for team training may be greater than that among teams that work together regularly under less time pressure to perform. Communication between team members and managing a crisis were critical aspects of an effective response team.
Workplace Physical Activity Interventions: A Systematic Review
Authors: To Quyen G. , Chen Ted T. L. , Magnussen Costan G. , To Kien G. 
Published: May 2013

Objective. To assess the effectiveness of workplace interventions in improving physical activity. Data Source. EBSCO research database (and all subdatabases). Study Inclusion and Exclusion Criteria. Articles were published from 2000 to 2010 in English, had appropriate designs, and measured employees' physical activity, energy consumption, and/or body mass index (BMI) as primary outcomes. Articles that did not meet the inclusion criteria were excluded. Data Extraction. Data extracted included study design, study population, duration, intervention activities, outcomes, and results. Data Synthesis. Data were synthesized into one table. Results of each relevant outcome including p values were combined. Results. Twelve (60%) of 20 selected interventions reported an improvement in physical activity level, steps, or BMI, and there was one slowed step reduction in the intervention group. Among these, 10 were less than 6 months in duration; 9 used pedometers; 6 applied Internet-based approaches; and 5 included activities targeting social and environmental levels. Seven of 8 interventions with pre-posttest and quasi-experimental controlled design showed improvement on at least one outcome. However, 7 of 12 randomized controlled trials (RCTs) did not prove effective in any outcome. Conclusion. Interventions that had less rigorous research designs, used pedometers, applied Internet-based approaches, and included activities at social and environmental levels were more likely to report being effective than those without these characteristics.
Large congenital nevus spilus—improved follow-up through the use of in vivo reflectance confocal microscopy
Authors: Prodinger Christine , Tatarski Rafaella , Laimer Martin , Ahlgrimm-Siess Verena 
Published: May 2013

Background: Nevus spilus (NS) is a potential precursor of melanoma; the vast majority of cases reported in the literature were histologically classified as superficial spreading melanoma.
Objective: To demonstrate the diagnostic value of reflectance confocal microscopy (RCM) in this subtype of congenital nevi.
Methods: We report a case of a large congenital NS with equivocal clinical and dermoscopic findings in which RCM was applied for diagnosis and follow-up.
Results: There was a good correlation of RCM with histopathology and a lack of dynamic changes during follow-up.
Conclusion: Our observations indicate that RCM, as a non-invasive tool, can be useful for diagnosis and follow-up of clinically and dermoscopically equivocal NS.
Does taping torso scars following dermatologic surgery improve scar appearance?
Authors: Rosengren Helena , Askew Deborah A. , Heal Clare , Buettner Petra G. , Humphreys Willliam O. , Semmens Lyndie A. 
Published: May 2013

Background: Studies show that patients are significantly less satisfied with torso scars than scars elsewhere. Though not an uncommon practice, it is unknown if application of adhesive tapes following dermatological surgery help improve cosmesis.
Objective: To determine the effect of taping sutured torso wounds on overall scar appearance, scar width and patient satisfaction with the scar.
Patients/Methods: Participants having elliptical torso skin excisions in a primary care setting in regional Australia were randomized in a single-blinded, controlled trial to 12 weeks taping (intervention) or usual care (control) following deep and subcuticular suturing. A blinded assessor reviewed scars at three and six months.
Results: Of 195 participants recruited, 136 (63 taped, 73 controls) completed six months of follow-up. Independent blinded assessment of overall scar appearance was significantly better in taped participants (p= 0.004). Taping reduced median scar width by 1 mm (p=0.02) and when stratified by gender, by 3.0 mm in males (p=0.04) and 1.0 mm in females (p=0.2). High participant scar satisfaction was not further improved by taping.
Conclusion: Taping elliptical torso wounds for 12 weeks after dermatologic surgery improved scar appearance at six months.
Modified β‐casein restores thermal reversibility of human carbonic anhydrase II: The salt bridge mechanism
Authors: Fallah‐Bagheri Azadeh , Moosavi‐Movahedi Ali Akbar , Taghizadeh Mohammad , Khodarahmi Reza , Ma'mani Leila , Bijari Nooshin , Bohlooli Mousa , Shafiee Abbas , Sheibani Nader , Saboury Ali Akbar 
Published: April 2013

AbstractModified β‐casein (mβ‐CN) was investigated as an efficient additive for thermal reversibility of human carbonic anhydrase II (HCA II) at pH 7.75. The mβ‐CN was obtained via modification of β‐casein (β‐CN) acidic residues using Woodward's reagent K. The effects of mβ‐CN on the reversibility and stability of HCA II were determined by differential scanning calorimetry, UV–vis, and 1‐anilinonaphthalene‐8‐sulfonic acid fluorescence spectroscopic methods. The mβ‐CN, as an additive, enhanced thermal reversibility of HCA II by 33%. Together, our results indicated that mβ‐CN is very efficient in decreasing thermal aggregation and enhancing the stability of HCA II. Using theoretical studies, we propose that the mechanism for thermal reversibility is mediated through formation of a salt bridge between the Woodward part of mβ‐CN and the Zn ion of HCA II.
Functional characterization of an ACCase subunit from the diatom Phaeodactylum tricornutum expressed in Escherichia coli
Authors: Xie Wei‐Hong , Pang Fei , Niu Ying‐Fang , Zhang Meng‐Han , Yang Wei‐Dong , Liu Jie‐Sheng , Yan Dao‐Guang , Li Hong‐Ye 
Published: April 2013

AbstractThe marine diatom Phaeodactylum tricornutum, a widely used forage species, has a storage lipid content of up to 30% dry cell weight. To explore the mechanism behind the high storage lipid accumulation in this diatom, acetyl‐CoA carboxylase (ACCase), which catalyzes the first committed step of the fatty acid biosynthetic pathway, was characterized in this study. A homogeneous type of ACCase (PtACC) was identified from P. tricornutum by homology searches. The first exon of the ACCase gene (PtACC‐1) was cloned. PtACC‐1 was fused with a Myc epitope tag and cloned into plasmid pMD18 driven by the LacZ promoter and expressed in Escherichia coli. The expression of the PtACC‐1‐Myc protein was verified by Western blot. The neutral lipid content in transformed E. coli increased substantially by twofold as determined by Nile red fluorescent dye staining. Concomitantly, ACCase activity increased by 1.72‐fold. The fatty acid composition, analyzed by GC‐MS, demonstrated a significant difference in the ratio of saturated fatty acids and monounsaturated fatty acids (MUFAs). MUFAs of PtACC‐1 expressing cells increased by 13%. This study represents the first characterization of the key domains of ACCase from a diatom and demonstrates high neutral lipid accumulation in E. coli expressing PtACC‐1, providing an additional genetic resource with the potential for biodiesel development.
Decrease in gastrointestinal absorption of roxithromycin in bile duct cannulated rats due to depletion of bile salts
Authors: Lee Joo Hyun , Park Young Ju , Oh Ju‐Hee , Lee Young‐Joo 
Published: April 2013

ABSTRACTThe purpose of this study was to investigate the effect of bile salts on gastrointestinal absorption and the plasma second peak phenomenon of roxithromycin in rats. The pharmacokinetic parameters of roxithromycin were calculated after single oral administration at a dose of 20 mg/kg in sham‐operated (control), bile duct cannulated (BDC) and bile salt co‐administered bile duct cannulated (BSBDC) rats. In BDC rats, the total area under the plasma concentration–time curve from time zero to time infinity (AUC0–∞) and the peak plasma concentration (Cmax) were significantly smaller (0.572‐fold) and lower (0.412‐fold), respectively, than those in the control rats. These values were recovered by co‐administration of bile salt (0.831‐ and 0.828‐fold for AUC0–∞ and Cmax compared with the control, respectively). Thus, the decreased absorption of roxithromycin in BDC rats could be due to a depletion of bile. The solubility of roxithromycin was 3.09‐fold increased at 30 mm of sodium taurocholate. The oral dosage regimen of roxithromycin could be changed in patients with bile deficiency or when the drug is administered to individuals on a high‐fat diet, if the present rat data can be extrapolated to humans. Copyright © 2013 John Wiley & Sons, Ltd.