bluuebunny/crossref_metadata_2025_split huggingface dataset:
Patrimony, Solitude and Obligation: Prodigal Sons and Absent Fathers
Authors: Duran Gimenez-Rico Isabel 
Published: December 2014

As a contribution to the verifiable moment that auto/biographical explorations of the father are undergoing in the first two decades of the 21st century, my paper focuses on four authors whose relational memoirs "go beyond the subject." In particular, I focus on a comparative analysis of three hybrid texts -Paul Auster's The Invention of Solitude (1982), Philip Roth's Patrimony (1991), and Richard Rodriguez's Days of Obligation: an Argument with my Mexican Father (1992)-, and I include a parallel reading of Dutch author Henri J. M. Nouwen's spiritual journey The Return of the Prodigal Son (1992). My transnational, transethnic reading of these very disparate versions of what has been called "patremoir" (Andre Gerard, 2012) or "patriography" (Couser, 2011) will explore how these authors mix their own portrait with the extended portrait of their (real or metaphoric) father, applying different myths, borrowing forms and strategies from literary antecedents, transgressing norms of familial secrecy and privacy, but -in the end- paying homage to their paternal legacy. This article was submitted on December 15th 2013 and first published on November 26th.
Structures of Tetrasilylmethane Derivatives C(SiXMe2)4 (X=H, F, Cl, Br) in the Gas Phase and their Dynamic Structures in Solution
Authors: Wann Derek A. , Young Stuart , Bätz Karin , Masters Sarah L. , Avent Anthony G. , Rankin David W. H. , Lickiss Paul D. 
Published: December 2014

Abstract
The structures of the molecules C(SiXMe2)4 (X=H, F, Cl, Br) have been determined by gas electron diffraction (GED). Ab initio calculations revealed nine potential minima for each species, with significant ranges of energies. For the H, F, Cl, and Br derivatives nine, seven, two, and two conformers were modelled, respectively, as they were quantum-chemically predicted to be present in measurable quantities. Variable-temperature 1H and 29Si solution-phase NMR studies and, where applicable, 13C NMR, 1H/29Si NMR shift-correlation, and 1H NMR saturation-transfer experiments are reported for C(SiXMe2)4 (X=H, Cl, Br, and also I). At low temperature in solution two conformers (one C1-symmetric and one C2-symmetric) are observed for each of C(SiXMe2)4 (X=Cl, Br, I), in agreement with the isolated molecule ab initio calculations carried out as part of this work for X=Cl, Br. C(SiHMe2)4 is present as a single C1-symmetric conformer in solution at the temperatures at which the NMR experiments were performed.
Hydrometallation (M = Al, Ga) of Silicon- and Germanium-centred Oligoalkynes
Authors: Uhl Werner , Bohnemann Jörg , Kappelt Benedikt , Malessa Kira , Rohling Martina , Tannert Jens , Layh Marcus , Hepp Alexander 
Published: December 2014

Abstract
Treatment of a variety of alkyl- and arylsilanes, R4-nSi(C≡C-R′)n, and -germanes, R4-nGe(C≡C-R′)n (1-7), with equimolar quantities of the dialkylmetal hydrides HMR″ 2 (M = Al, Ga; R″ = CMe3, CH2CHMe2) yielded by reduction of a single alkynyl group a series of mixed alkenyl-alkynyl compounds R4-nSi(C≡C-R′)n-1{C(MR″2) =CHR′} (n = 2, 3) and R2Ge(C≡C-R′){C[M(CMe3)2]=CHR′} (8-13). Reactions with two equivalents of the hydrides afforded the dialkenyl compounds R2E{C[(M(CMe3)2]=CHR′}2 (E = Si, Ge, 14-17), Ge(C≡C- CMe3)2{C[Ga(CMe3)2]=CH-CMe3}2 (18) and MeSi(C≡C-p-Tol){C[Ga(CMe3)2]=CH-p-Tol}2 (19) [R = Ph, Mes, Me, C6F5; R′ = CMe3, Ph). Most of the products were characterised by Xray crystallography which for the alkenyl-alkynyl derivatives revealed short intramolecular contacts between the coordinatively unsaturated metal atoms and the a-C atoms of unreacted ethynyl groups Cα≡C-R′.
Analysis of nonradiative recombination mechanisms and their impacts on the device performance of InGaN/GaN light-emitting diodes
Authors: Han Dong-Pyo , Oh Chan-Hyoung , Zheng Dong-Guang , Kim Hyunsung , Shim Jong-In , Kim Kyu-Sang , Shin Dong-Soo 
Published: December 2014

Abstract
We investigate the nonradiative recombination mechanisms of two conventional InGaN/GaN-based blue light-emitting diodes with different threading dislocation densities (TDDs). The current–voltage, the ideality factor, and the slope of the light-versus-current curve on log scales are analyzed to distinguish the dominant nonradiative recombination mechanisms at room temperature. Through the analysis, we infer the dominant nonradiative recombination mechanisms to be the Shockley–Read–Hall process for the sample with a low TDD (∼1 × 108 cm−2) and the defect-assisted tunneling for the sample with a high TDD (∼1 × 109 cm−2). For more detailed analysis of the nonradiative recombination mechanisms and their impacts on the device performance, we execute the temperature-dependent photovoltage and temperature-dependent electroluminescence efficiency experiments. The sample with a low TDD is found to be more prone to the carrier spill-over at cryogenic temperatures due to the deactivation of point defects, while the sample with a high TDD is more robust to the operation at cryogenic temperatures owing to the relative insensitiveness of the defect-assisted tunneling to temperature.
Resorbable Synthetic Mesh Supported With Omentum Flap in the Treatment of Giant Hiatal Hernia
Authors: Pérez Lara F. J. , Marín R. , del Rey A. , Oliva H. 
Published: December 2014

Abstract
Covering a large hiatal hernia with a mesh has become a basic procedure in the last few years. However, mesh implants are associated with high complication rates (esophageal erosion, perforation, fistula, etc.). We propose using a synthetic resorbable mesh supported with an omental flap as a possible solution to this problem. A 54-year-old female patient with a large hiatal defect (9 cm) was laparoscopically implanted with a synthetic resorbable mesh supported with an omental flap. The surgical procedure was successful and the patient was discharged on postoperative day 2. On a follow-up examination 6 months after surgery, she remained free of relapse or complication signs. Supporting an implanted resorbable mesh with an omental flap may be a solution to the problems posed by large esophageal hiatus defects. However, more studies based on larger patient samples and longer follow-up periods are necessary.
Glasgow Prognostic Score (GPS) Can Be a Useful Indicator to Determine Prognosis of Patients With Colorectal Carcinoma
Authors: Nozoe Tadahiro , Matono Rumi , Ijichi Hideki , Ohga Takefumi , Ezaki Takahiro 
Published: December 2014

Abstract
The Glasgow Prognostic Score (GPS), an inflammation-based score, has been used to predict the biologic behavior of malignant tumors. The aim of the current study was to elucidate a further significance of GPS in colorectal carcinoma. Correlation of GPS and modified GPS (mGPS), which are composed of combined score provided for serum elevation of C-reactive protein and hypoalbuminemia examined before surgical treatment, with clinicopathologic features was investigated in 272 patients with colorectal carcinoma. Survival of GPS 1 patients was significantly worse than that of GPS 0 patients (P= 0.009), and survival of GPS 2 patients was significantly worse than that of GPS 1 patients (P &lt; 0.0001). Similarly, survival of mGPS 1 patients was significantly worse than that of mGPS 0 patients (P = 0.009), and survival of mGPS 2 patients was significantly worse than that of mGPS 1 patients (P = 0.0006). Multivariate analysis demonstrated that GPS (P &lt; 0.0001) as well as tumor stage (P= 0.004) and venous invasion (P = 0.011) were factors independently associated with worse prognosis. Both GPS and mGPS could classify outcome of patients with a clear stratification, and could be applied as prognostic indicators in colorectal carcinoma.
Definitive Chemoradiotherapy and Salvage Esophagectomy for Esophageal Cancer Associated With Multiple Lung Metastases: A Case Report
Authors: Fujinaka Yoshihiko , Morita Masaru , Ohga Takefumi , Kakeji Yoshihiro , Yano Tokujiro , Maehara Yoshihiko 
Published: December 2014

Abstract
The prognosis of esophageal cancer with distant metastasis is dismal. We report a 70-year-old man with esophageal cancer and multiple lung and lymph node metastases. Complete response was achieved following definitive chemoradiotherapy. Twenty-four months after the initial chemoradiotherapy, local recurrence was detected but there was no evidence of distant metastasis. Therefore, the patient underwent salvage esophagectomy. The surgery was well tolerated without any postoperative complications. The patient is still alive 48 months after the salvage surgery. Our experience suggests that salvage esophagectomy is an important component of multimodal therapy for the recurrence of esophageal cancer.
Rectal Cancer With Disseminated Carcinomatosis of the Bone Marrow: Report of a Case
Authors: Nakashima Yuichiro , Takeishi Kazuki , Guntani Atsushi , Tsujita Eiji , Yoshinaga Keiji , Matsuyama Ayumi , Hamatake Motoharu , Maeda Takashi , Tsutsui Shinichi , Matsuda Hiroyuki , Fujihara Megumu , Ishida Teruyoshi 
Published: December 2014

Abstract
We report a rare case of disseminated carcinomatosis of the bone marrow from rectal cancer with disseminated intravascular coagulation (DIC). A 65-year-old man was admitted with melena and low back pain at rest. X-ray examination showed rectal cancer with multiple bone metastases. Laboratory examination showed severe anemia and DIC. Histologic examination showed disseminated carcinomatosis of the bone marrow. The DIC was considered to be caused by disseminated carcinomatosis of the bone marrow from rectal cancer, and we immediately started treatment with anti-DIC therapy and anticancer chemotherapy with the modified FOLFOX6 regimen (mFOLFOX6). After some response to therapy, the patient's general condition deteriorated, and he died 128 days after admission. This is the first English report showing disseminated carcinomatosis of the bone marrow from colorectal cancer treated with mFOLFOX6.
Multiple Metastatic Malignant Melanoma Presenting Intraluminal Gallbladder Bleeding
Authors: Onozawa Hisashi , Saito Motonobu , Yoshida Sayaka , Sakuma Takeshi , Matsuzaki Masami , Katagata Naoto , Watanabe Fumiaki , Yamaguchi Yoshiko , Takenoshita Seiichi , Nomizu Tadashi 
Published: December 2014

Abstract
We report a case of malignant melanoma of unknown primary origin presenting metastasis in various organs as well as intraluminal gallbladder bleeding due to gallbladder metastasis. A 58-year-old woman was diagnosed with stage IV metastatic malignant melanoma. Because she exhibited acute cholecystitis and hemobilia due to malignant melanoma of the gallbladder, laparoscopic cholecystectomy was performed to relieve the symptoms. The resected gallbladder specimen showed a pedunculated black mass indicating malignant melanoma. Pathologic examination and immunohistochemical analysis revealed malignant melanoma of the gallbladder. Only a few cases of gallbladder malignant melanoma presenting hemobilia have been reported; here we present our case, including the experience of multidisciplinary treatment.
Statistical analysis of the geomagnetic response to different solar wind drivers and the dependence on storm intensity
Authors: Katus R. M. , Liemohn M. W. , Ionides E. L. , Ilie R. , Welling D. , Sarno‐Smith L. K. 
Published: December 2014

AbstractGeomagnetic storms start with activity on the Sun that causes propagation of magnetized plasma structures in the solar wind. The type of solar activity is used to classify the plasma structures as being either interplanetary coronal mass ejection (ICME) or corotating interaction region (CIR) driven. The ICME‐driven events are further classified as either magnetic cloud (MC) driven or sheath (SH) driven by the geoeffective structure responsible for the peak of the storm. The geoeffective solar wind flow then interacts with the magnetosphere producing a disturbance in near‐Earth space. It is commonly believed that a SH‐driven event behaves more like a CIR‐driven event than a MC‐driven event; however, in our analysis this is not the case. In this study, geomagnetic storms are investigated statistically with respect to the solar wind driver and the intensity of the events. We use the Hot Electron and Ion Drift Integrator (HEIDI) model to simulate the inner magnetospheric hot ion population during all of the storms classified as intense (Dstmin ≤ −100 nT) within solar cycle 23 (1996–2005). HEIDI is configured four different ways using either the Volland‐Stern or self‐consistent electric field and either event‐based Los Alamos National Laboratory (LANL) magnetospheric plasma analyzer (MPA) data or a reanalyzed lower resolution version of the data that provides spatial resolution. Presenting the simulation results, geomagnetic data, and solar wind data along a normalized epoch timeline shows the average behavior throughout a typical storm of each classification. The error along the epoch timeline for each HEIDI configuration is used to rate the model's performance. We also subgrouped the storms based on the magnitude of the minimum Dst. We found that typically the LANL MPA data provide the best outer boundary condition. Additionally, the self‐consistent electric field better reproduces SH‐ and MC‐driven events throughout most of the storm timeline, but the Volland‐Stern electric field better reproduces CIR‐driven events. Contrary to what we expect, examination of the HEIDI model results and solar wind data shows that SH‐driven events behave more like MC‐driven events than CIR‐driven storms.
Quantifying the energy dissipation of overriding plate deformation in three‐dimensional subduction models
Authors: Chen Zhihao , Schellart Wouter P. , Duarte João C. 
Published: December 2014

AbstractIn a subduction system the force and the energy required to deform the overriding plate are generally thought to come from the negative buoyancy of the subducted slab and its potential energy, respectively. Such deformation might involve extension and back‐arc basin formation or shortening and mountain building. How much of the slab's potential energy is consumed during overriding plate deformation remains unknown. In this work, we present dynamic three‐dimensional laboratory experiments of progressive subduction with an overriding plate to quantify the force (FOPD) that drives overriding plate deformation and the associated energy dissipation rate (ΦOPD), and we compare them with the negative buoyancy (FBU) of the subducted slab and its total potential energy release rate (ΦBU), respectively. We varied the viscosity ratio between the plates and the sublithospheric upper mantle with ηSP/ηUM = 157–560 and the thickness of the overriding plate with TOP = 0.5–2.5 cm (scaling to 25–125 km in nature). The results show that FOPD/FBU has average values of 0.5–2.0%, with a maximum of 5.3%, and ΦOPD/ΦBU has average values of 0.05–0.30%, with a maximum of 0.41%. The results indicate that only a small portion of the negative buoyancy of the slab and its potential energy are used to deform the overriding plate. Our models also suggest that the force required to deform the overriding plate is of comparable magnitude as the ridge push force. Furthermore, we show that in subduction models with an overriding plate bending dissipation at the subduction zone hinge remains low (3–15% during steady state subduction).
Carbon dioxide evasion from headwater systems strongly contributes to the total export of carbon from a small boreal lake catchment
Authors: Kokic Jovana , Wallin Marcus B. , Chmiel Hannah E. , Denfeld Blaize A. , Sobek Sebastian 
Published: December 2014

AbstractInland waters are hotspots for carbon (C) cycling and therefore important for landscape C budgets. Small streams and lakes are particularly important; however, quantifying C fluxes is difficult and has rarely been done for the entire aquatic continuum, composed of connected streams and lakes within the same catchment. We investigated carbon dioxide (CO2) evasion and fluvial fluxes of dissolved inorganic carbon and dissolved organic carbon (DIC and DOC) in stream and lake systems within the 2.3 km2 catchment of a small boreal lake. Our results show pronounced spatial and temporal variability in C fluxes even at a small spatial scale. C loss from the catchment through CO2 evasion from headwaters for the total open water‐sampling period was 9.7 g C m−2 catchment, dominating the total catchment C loss (including CO2 evasion, DIC, and DOC export from the lake, which were 2.7, 0.2, and 5.2 g C m−2 catchment, respectively). Aquatic CO2 evasion was dominated by headwater streams that occupy ~0.1% of the catchment but contributed 65% to the total aquatic CO2 evasion from the catchment. The importance of streams was mainly an effect of the higher gas transfer velocities than compared to lakes (median, 67 and 2.2 cm h−1, respectively). Accurately estimating the contribution of C fluxes from headwater streams, particularly the temporal and spatial dynamics in their gas transfer velocity, is key to landscape‐scale C budgets. This study demonstrates that CO2 evasion from headwaters can be the major pathway of C loss from boreal catchments, even at a small spatial scale.
Observational evidence for impacts of vegetation change on local surface climate over northern China using the Granger causality test
Authors: Jiang Bo , Liang Shunlin , Yuan Wenping 
Published: December 2014

AbstractThe three‐north region in China (northeastern, northwestern, and northern China) is one of the most environmentally vulnerable regions in the country. To improve the local natural environment, the Chinese government launched the Three‐North Shelter Forest Program, one of the largest afforestation/reforestation programs in the world. This program has led to significant changes in vegetation. Although many studies have evaluated the impacts of vegetation changes on local climate in this region, their results are highly inconsistent. In this study, evidence for local monthly climate impacts of vegetation change was investigated using remotely sensed data and ground meteorological measurements during the growing season (May to September) from 1982 to 2011 using the bivariate Granger causality test. The results showed that the local near‐surface climate is sensitive mostly to vegetation changes characterized by the normalized difference vegetation index (NDVI) in arid and semiarid regions and that vegetation plays a more important role in influencing hydroclimate in the arid/semiarid zones than in other zones, which has great implications for water resources in this dry region. Moreover, NDVI changes in northeastern China have a significantly negative influence on air tembut no other climatic variables, whereas the test results in northern China is not as objective as the other zones due to the rapid urbanization. All these results suggest that the local climate is very sensitive to the variations in vegetation in arid and semiarid regions, so extra caution should be taken when planting trees in this area.
Frequently Asked Questions
Authors: Wittekind Ch. , Henson D. E. , Hutter R. V. P. , Sobin L. H. 
Published: December 2014

Abstract
The TNM Supplement: A Commentary on Uniform Use, provides explanations and examples to answer many questions that might arise during the daily use of TNM, particularly in unusual cases. The Frequently Asked Questions (FAQ) presented here were derived from the activities of the TNM web site's “Help Desk” based on questions received by the TNM Prognostic Factors Project Committee concerning the use of TNM and how to interpret rules in specific situations.
Mutations in PTRH2 cause novel infantile‐onset multisystem disease with intellectual disability, microcephaly, progressive ataxia, and muscle weakness
Authors: Hu Hao , Matter Michelle L. , Issa‐Jahns Lina , Jijiwa Mayumi , Kraemer Nadine , Musante Luciana , de la Vega Michelle , Ninnemann Olaf , Schindler Detlev , Damatova Natalia , Eirich Katharina , Sifringer Marco , Schrötter Sandra , Eickholt Britta J. , van den Heuvel Lambert , Casamina Chanel , Stoltenburg‐Didinger Gisela , Ropers Hans‐Hilger , Wienker Thomas F. , Hübner Christoph , Kaindl Angela M. 
Published: December 2014

AbstractObjectiveTo identify the cause of a so‐far unreported phenotype of infantile‐onset multisystem neurologic, endocrine, and pancreatic disease (IMNEPD).MethodsWe characterized a consanguineous family of Yazidian‐Turkish descent with IMNEPD. The two affected children suffer from intellectual disability, postnatal microcephaly, growth retardation, progressive ataxia, distal muscle weakness, peripheral demyelinating sensorimotor neuropathy, sensorineural deafness, exocrine pancreas insufficiency, hypothyroidism, and show signs of liver fibrosis. We performed whole‐exome sequencing followed by bioinformatic analysis and Sanger sequencing on affected and unaffected family members. The effect of mutations in the candidate gene was studied in wild‐type and mutant mice and in patient and control fibroblasts.ResultsIn a consanguineous family with two individuals with IMNEPD, we identified a homozygous frameshift mutation in the previously not disease‐associated peptidyl‐tRNA hydrolase 2 (PTRH2) gene. PTRH2 encodes a primarily mitochondrial protein involved in integrin‐mediated cell survival and apoptosis signaling. We show that PTRH2 is highly expressed in the developing brain and is a key determinant in maintaining cell survival during human tissue development. Moreover, we link PTRH2 to the mTOR pathway and thus the control of cell size. The pathology suggested by the human phenotype and neuroimaging studies is supported by analysis of mutant mice and patient fibroblasts.InterpretationWe report a novel disease phenotype, show that the genetic cause is a homozygous mutation in the PTRH2 gene, and demonstrate functional effects in mouse and human tissues. Mutations in PTRH2 should be considered in patients with undiagnosed multisystem neurologic, endocrine, and pancreatic disease.
ortho‐, meta‐, and para‐Dihydroindenofluorene Derivatives as Host Materials for Phosphorescent OLEDs
Authors: Romain Maxime , Thiery Sébastien , Shirinskaya Anna , Declairieux Céline , Tondelier Denis , Geffroy Bernard , Jeannin Olivier , Rault‐Berthelot Joëlle , Métivier Rémi , Poriel Cyril 
Published: December 2014

AbstractThis work reports the first structure–properties relationship study of ortho [2,1‐c]‐, meta [1,2‐a]‐, and para [1,2‐b]dihydroindenofluorenes, highlighting the influence of bridge rigidification on the electronic properties. This study has made it possible to devise an extended π‐conjugated molecule with both a high triplet state energy level and excellent thermal and morphological stability. As a proof of concept, dihydroindenofluorenes were used as the host in sky‐blue phosphorescent organic light‐emitting diodes (PhOLEDs) with high performance.
Quantitative Trace Analysis of Complex Mixtures Using SABRE Hyperpolarization
Authors: Eshuis Nan , van Weerdenburg Bram J. A. , Feiters Martin C. , Rutjes Floris P. J. T. , Wijmenga Sybren S. , Tessari Marco 
Published: December 2014

AbstractSignal amplification by reversible exchange (SABRE) is an emerging nuclear spin hyperpolarization technique that strongly enhances NMR signals of small molecules in solution. However, such signal enhancements have never been exploited for concentration determination, as the efficiency of SABRE can strongly vary between different substrates or even between nuclear spins in the same molecule. The first application of SABRE for the quantitative analysis of a complex mixture is now reported. Despite the inherent complexity of the system under investigation, which involves thousands of competing binding equilibria, analytes at concentrations in the low micromolar range could be quantified from single‐scan SABRE spectra using a standard‐addition approach.