bluuebunny/crossref_metadata_2025_split huggingface dataset:
O conhecimento e acesso ao script de base segura e a percepção de suporte social em mães com crianças em idade pré-escolar
Authors: Branco Irina , Monteiro Lígia , Veríssimo Manuela 
Published: June 2015

O presente estudo analisou a relação entre o conhecimento e acesso ao script de base de mães e pais e a percepção da qualidade do suporte social recebido. Participaram 37 mães com crianças em idade pré-escolar. De modo a aceder às representações de vinculação utilizou-se as Narrativas de Representação da Vinculação em Adultos; tendo a competência verbal sido controlada com o recurso ao Índice de Compreensão Verbal (W). O Suporte Social percebido foi avaliado com base na Escala de Satisfação com o Suporte Social. Os resultados indicam associações entre a segurança e dimensões do suporte social. Os resultados são discutidos no contexto da teoria da vinculação de Bowlby e Ainsworth, e do Suporte Social Percebido.
Determination of caftaric acid in tincture and rose water obtained from Rosae damascenae flores
Authors: Popescu Antoanela , Matei Nicoleta , Roncea Florentina , Miresan Horatiu , Pavalache Georgeta 
Published: June 2015

Abstract
Polyphenolic compounds were determined from a pharmaceutical (tincture) and a cosmetic preparation (rose water), both obtained from the Rosae damascenae flores. Separation of the phenolic compounds was done by a HPLC method, using a Zorbax XDB or equivalent column C18, 250 mm x 4,6 mm; 5 μm. A gradient elution was performed with phosphoric acid and acetonitrile eluted under gradient conditions. The flow rate was 1.5 mL/min and the injection volume was 20 μL. HPLC method for determination of caftaric acid presented in this paper, has been validated. The results were statistically analyzed with SPSS 10 software.
Determination of loratadine in pharmaceuticals by a spectrophotometric method
Authors: Pavalache Georgeta , Matei Nicoleta , Popescu Antoanela 
Published: June 2015

Abstract
The spectrophotometric method for determination of loratadine using tetraiodomercurate has been applied in various pharmaceutical formulations. The results confirmed that recovery value is optimum and the method is valid, thus it can be used in quality control and evaluation of loratadine tablets, oral formulations of mixed composition, oral solutions, etc. The method is easy and simple to apply, does not require complicated equipment and spectrophotometric reading time is reduced, which allows a large number of analyzes in a relatively short time.
Applications of a DAD-HPLC method for determination of loratadine on biological samples
Authors: Pavalache Georgeta , Matei Nicoleta , Popescu Antoanela , Schroder Verginica 
Published: June 2015

Abstract
The aim of research is to assess the active substance by a HPLC method for the separation and quantitative determination of loratadine. The method has been developed and validated on the standard solutions, in previous research. The current study was undertaken to present the results obtained from loratadine determination in biological samples (human serum, urine and breast milk). These results may be applicable on patients with different physiological conditions (aging, pregnancy or recently giving birth, etc.) and pathological conditions which may interfere with the metabolism of loratadine. The used HPLC method detected loratadine concentrations in human serum samples, respectively urine samples, at 2 hours after drug administration. The method detected traces of loratadine which passed into breast milk, as well. Data were statistically interpreted using MED CALC 10.2 software. These results show that the applied method can be used for quantitative analysis of loratadine in biological fluids (all permissible limits of quality specifications being in the range 95- 105%).
Cadmium and lead occurrence in soil and grape from Murfatlar Vineyard
Authors: Matei Nicoleta , Popescu Antoanela , Radu Gabriel-Lucian , Artem Victoria , Pavalache Georgeta 
Published: June 2015

Abstract
The study investigates the pollution with heavy metals of grapes and soil. The grapes nourish from the respective soil, with all existing substances: either nutrients or toxic materials. This link, between grapes and soil, made mandatory to focus on observing the level of toxic materials in both samples grapes and land. The aim of this research is to analyze the level of Cd and Pb in Vitis vinifera L. grape fruits and soil, by flame atomic absorption spectrometry (FAAS) method. The grapes and the soil used in this work were sampled from the Murfatlar City, a nonindustrial area, placed far from the car traffic pollution. Cd and Pb were quantified, after the chemical mineralization of the samples using nitric acid. It can be noticed that the values of cadmium and lead concentrations in grapes were lower than the recommendable maximum limit.
Optimal Product R&D Policies with Endogenous Quality Choices and Unilateral Spillover
Authors: Taba Yumiko 
Published: June 2015

Abstract
This study derives non-cooperative and cooperative optimal product research and development (R&D) policies of a country with a high-quality firm and a country with a low-quality firm in the presence of technology spillover under Cournot and Bertrand competitions in an international duopoly. When the respective governments determine their R&D policies non-cooperatively, optimal policies for both countries involve an R&D tax (subsidy) if spillover is large (small). When the governments choose their R&D policies cooperatively, a tax is always optimal for the country with low-quality firm and a subsidy (tax) is optimal for the country with high-quality firm if spillover is large (small). In addition, we show that the non-cooperative optimal product R&D Policy is tax for a wider range of spillover effects under Cournot competition, compared to the case of Bertrand competition.
Performance characteristics of the VIDAS® 25-OH Vitamin D Total assay – comparison with four immunoassays and two liquid chromatography-tandem mass spectrometry methods in a multicentric study
Authors: Moreau Emmanuel , Bächer Silvia , Mery Sophie , Goff Caroline Le , Piga Nadia , Vogeser Michael , Hausmann Michael , Cavalier Etienne 
Published: June 2015

AbstractThe study was conducted to evaluate the analytical and clinical performance of the VIDASVIDASThe VIDASThe VIDAS
Correlates of serum hepcidin levels and its association with cardiovascular disease in an elderly general population
Authors: Pechlaner Raimund , Kiechl Stefan , Mayr Manuel , Santer Peter , Weger Siegfried , Haschka David , Bansal Sukhvinder S. , Willeit Johann , Weiss Günter 
Published: June 2015

AbstractThe expression of the key iron regulatory hormone hepcidin is regulated by iron availability, inflammation, hormones, hypoxia, and anaemia. Increased serum concentrations of hepcidin have recently been linked to atherosclerosis. We studied demographic, haematologic, biochemical, and dietary correlates of serum hepcidin levels and its associations with incident cardiovascular disease and with carotid atherosclerosis.Serum hepcidin concentrations were measured by tandem mass spectrometry in samples taken in 2000 from 675 infection-free participants of the prospective population-based Bruneck study (age, mean±standard deviation, 66.0±10.2; 48.1% male). Blood parameters were measured by standard methods. Dietary intakes of iron and alcohol were surveyed with a food frequency questionnaire. Carotid atherosclerosis (365 cases) was assessed by ultrasound and subjects were observed for incident stroke, myocardial infarction, or sudden cardiac death (91 events) until 2010.Median (interquartile range) hepcidin levels were 2.27 nM (0.86, 4.15). Most hepcidin correlates were in line with hepcidin as an indicator of iron stores. Independently of ferritin, hepcidin was related directly to physical activity (p=0.024) and fibrinogen (p<0.0001), and inversely to alcohol intake (p=0.006), haemoglobin (p=0.027), and γ-glutamyltransferase (p<0.0001). Hepcidin and hepcidin-to-ferritin ratio were not associated with prevalent carotid atherosclerosis (p=0.43 and p=0.79) or with incident cardiovascular disease (p=0.62 and p=0.33).In this random sample of the general community, fibrinogen and γ-glutamyltransferase were the most significant hepcidin correlates independent of iron stores, and hepcidin was related to neither atherosclerosis nor cardiovascular disease.
Clinical utility of one versus two faecal immunochemical test samples in the detection of advanced colorectal neoplasia in symptomatic patients
Authors: Auge Josep Maria , Fraser Callum G. , Rodriguez Cristina , Roset Alba , Lopez-Ceron Maria , Grau Jaume , Castells Antoni , Jimenez Wladimiro 
Published: June 2015

AbstractThe utility of faecal immunochemical tests (FIT) in assessment of symptomatic patients with lower gastrointestinal symptoms has not been well explored. The aims of this study were to evaluate the diagnostic yield for advanced colorectal neoplasia (ACRN) in symptomatic patients using the first of two FIT samples (FIT/1) and the higher concentration of two FIT samples (FIT/max).Samples from two consecutive bowel motions from 208 symptomatic patients who required colonoscopy were analysed using the HM-JACKarc analyser (Kyowa Medex Co., Ltd., Tokyo, Japan). Patients were categorised into two groups: patients with any ACRN and individuals with other diagnoses or normal colonoscopy.Colonoscopy detected ACRN in 29 patients. In these patients, FIT/1 and FIT/max were significantly higher than in patients with low-risk adenoma (p=0.006 and p=0.024), other findings (p=0.002 and p=0.002) and normal colonoscopy (p<0.001 and p<0.001). The areas under the curves (AUC) of FIT/1 and FIT/max were 0.71 and 0.69, respectively. Undetectable FIT/1 rules out 96.6% of ACRN and the specificity was 10.6%. Increasing the FIT/1 cut-off to 10 μg Hb/g faeces, sensitivity and specificity were 34.5% and 87.2%, respectively. Similar results were obtained using FIT/max with 20 μg Hb/g faeces cut-off, providing a sensitivity and specificity of 34.5% and 85.6%, respectively.Undetectable FIT is a good strategy to rule-out ACRN in symptomatic patients. The diagnostic yield of collecting two samples for FIT can be achieved with one sample, but a lower faecal haemoglobin concentrations (f-Hb) cut-off is required.
Homocitrulline: a new marker for differentiating acute from chronic renal failure
Authors: Desmons Aurore , Jaisson Stéphane , Pietrement Christine , Rieu Philippe , Wynckel Alain , Gillery Philippe 
Published: June 2015

AbstractCarbamylation is a non-enzymatic post-translational modification of proteins characterized by the addition of isocyanic acid to amino groups. As isocyanic acid mainly originates from the spontaneous dissociation of urea, carbamylation rate is increased during renal failure. The aim of the study was to evaluate serum homocitrulline (HCit), which results from the carbamylation of ε-amino groups of lysine (Lys) residues, in acute renal failure (ARF) and to determine if it could be useful for differentiating acute from chronic renal failure (CRF).In total, 213 patients with renal failure referred to the nephrology department of the university hospital of Reims were included. Patients were classified into three groups: patients with ARF (ARF group, n=39), patients with CRF complicated with ARF (A/CRF group, n=29) and patients with CRF (CRF group, n=145). Serum HCit concentrations were measured by LC-MS/MS. Concentration kinetics of HCit and urea were studied in patients suffering from ARF. The HCit thresholds distinguishing ARF and CRF were investigated.HCit concentrations increased in ARF patients reaching a peak delayed compared to urea concentration peak. HCit concentrations were positively correlated with urea concentrations (r=0.51) and with the time elapsed since the estimated onset of ARF (r=0.57). Serum HCit concentrations were higher (p<0.05) in CRF group compared to ARF group. The receiver operating characteristic curve analysis showed that HCit concentrations <289 μmol/mol Lys were predictive of ARF (Sensitivity: 83%, Specificity: 72%, AUC: 0.856).Our results demonstrate that HCit is a promising biomarker for distinguishing between ARF and CRF patients.
Lipiduria – with special relevance to Fabry disease
Authors: Becker Gavin J. , Nicholls Kathleen 
Published: June 2015

AbstractExamination of the urine under the microscope using polarised light is invaluable for detecting and identifying lipid particles. Attention to the shape of these Maltese cross bearing bodies can distinguish conventional fat particles from Fabry bodies with great sensitivity and specificity across a wide phenotypic spectrum. This could be a cheap and rapid tool for screening subjects suspected of having Fabry disease for renal involvement. It remains to be seen whether there is value in integrating polarised light into automated urine microscopy machines, but potentially this could greatly help the pathologist or nephrologist in identifying unusual urinary particles, and broaden the capacity for larger scale screening.
Corrosion inhibition behavior of two quinoline chalcones: insights from density functional theory
Authors: Gece Gökhan 
Published: June 2015

AbstractThere has been a considerable surge of experimental inquiry in recent years into understanding the factors responsible for the corrosion inhibition efficiency of chalcones; however, the question of what actually determines the efficiency still remains a topic of debate. In this study, the dependence of the inhibition effect of such two compounds, namely, 3-(3-oxo-3-phenyl-propenyl)-1H-quinolin-2-one and 3-(3-oxo-3-phenyl-propenyl)-1H-benzoquinolin-2-one, on their molecular and electronic structure is analyzed using density functional theory calculations. In agreement with experiments, this study found strong evidence to link corrosion inhibition property of the compounds to their actual molecular structures in acidic media.
Variability of sulfur speciation in sediments from Sulejów,Turawa and Siemianówka dam reservoirs (Poland)
Authors: Drzewicki Wojciech , Ciężka Monika , Jezierski Piotr , Jędrysek Mariusz Orion 
Published: June 2015

Abstract
A study on sulfur circulation in sediments wascarried out in dam reservoirs (Sulejów, Siemianówka, Turawa)with different hydrological and age characteristicsas well as with a different level of sediment accumulationand organic matter content.Differences in the isotopic composition of SO2−
4 in the watercolumn and small variations in the concentration ofthis ion were observed in the Turawa reservoir. The investigationsdid not show vertical variation in the watercolumnconcentrations and isotopic composition. This isdue to the small depths of the reservoir and mixing of water.A part of sulfate sulfur from the water column is reducedby incorporating it into cell structures, while a partof it is deposited in the sediment. The study revealed asmall exchange of SO2−
4 between thewater column and thesediment. Depending on the season of the year and thesediment sampling site, biogeochemical transformationsof sulfur species are observed.A significant variation in the biogeochemical processeswas found between the Siemianówka and Sulejów reservoirs,both in the concentrations and in the isotopic compositionof particular sulfur species. This primarily resultsfrom the different characteristics of either of these reservoirs(flows, sedimentation, and material discharge to thelake). The main source of sulfur supplied to the sedimentsin the Siemianówka reservoir is organic sulfur contained inorganic matter deposited at the bottom. In the sediment,organic sulfur is bacterially oxidized and fixed as SO2−
4 .This is manifested in a substantial enrichment of sulfate in34S. The presence of polysulfides was found in both reservoirs,but a distinct depletion of δ34S(S2−) in the light sulfurisotope was observed in the Siemianówka reservoir. Ina part of the Sulejów reservoir, polysulfides are oxidized toSO2−
4 ,probably at the sediment/water interface.
Impact of landfilling of red mud waste on local environment – the case of Górka / Wpływ Składowania Odpadów Typu Red Mud Na Środowisko Lokalne Na Przykładzie „Górki“
Authors: Pietrzyk-Sokulska Elżbieta , Kulczycka Joanna 
Published: June 2015

Streszczenie
Pomimo zaostrzenia wymagań środowiskowych, na terenie Europy nadal występują zdegra- dowane obszary przemysłowe, które stanowią poważane zagrożenie dla środowiska i zdrowia ludzi. Jednym z nich są składowiska odpadów typu red mud o silnie alkalicznym odczynie, często za- wierające toksyczne związki. Na całym świecie jest zmagazynowanych około 2,7 mld Mg odpadów typu red mud. W artykule przedstawiono problemy związane ze składowiskiem odpadów tego typu, zlokalizowanym w opuszczonym kamieniołomie pomarglowym w Trzebini (Polska połud- niowa). Identyfikacja zachodzących w nim zmian w ostatnich latach oraz związanego z nimi wpły- wu na środowisko pozwoliła wskazać sposób postępowania minimalizujący istniejące zagro- żenia. Przeprowadzone w trakcie 30-lctniego istnienia wyrobiska badania wskazują, iż zachodząca w tym czasie infiltracja zgromadzonych na zwałowisku odpadów przez wody deszczowe i podziemne była powodem powstania głębokiego zbiornika silnie alkalicznych odcieków (pH >13), które mogą negatywnie oddziaływać na środowisko wodno-glebowc. W 2000 r. podniesienie poziomu odcieków w zbiorniku do krawędzi wyrobiska zagroziło ich przelaniem na otaczający teren, stwarzając zagro- żenie dla zdrowia ludzi. Działania zaradcze, w postaci odpompowywania nadmiaru odcieków, zapo- biegły czasowo ekologicznej katastrofie. Ze względu na to, że skład chemiczny odpadów red mud może stwarzać potencjalne zagrożenie dla środowiska ze względu na wypłukiwanie z nich substancji toksycznych, które mogą przyczynić się do skażenia gleby i wody wokół zbiornika, szczegółowe analizy odcieków ze zbiornika Górka, gleby wokół zbiornika Górka, wody i osadów dennych w jeziorze Balaton (znajdującego się w pobliżu składowiska) zostały przeanalizowane. Składo- wany odpad przestanie stanowić zagrożenie dopiero dzięki całkowitej utylizacji. Może to nastąpić w roku 2015 dzięki realizacji kompleksowych prac rekultywacyjnych dofinansowanych z funduszy rządowych i UE.
Wpływ wybranych zagrożeń środowiskowych na właściwości hydrofobowe drobnodyspersyjnego wapienia / The Influence of Chosen Environmental Hazards on Hydrophobic Properties of Fine Dispersional Limestone
Authors: Vogt Elżbieta , Horak Anna , Wolak Eliza , Kanik Urszula 
Published: June 2015

StreszczeniePrzestawiono wyniki badań zmiany hydrofobowych właściwości drobnodyspersyjnego wapienia pod wpływem wybranych czynników korozyjnych. Badano dwie frakcje ziarnowe drobnodysper- syjnego wapienia, o średnicy ziaren zgodnie z danymi producenta (Kopalnia Wapienia Czatkowice) wynoszącej odpowiednio: dla mączki wapiennej poniżej 80 um oraz piasku wapiennego z przedziału 100-400 um. Badano również mączką wapienną hydrofobizowaną w kamieniołomie wapieni i margli cementowni w Małogoszczy. Badano materiały surowe oraz hydrofobizowanc za pomocą kwasu stearynowego, preparatu silikonowego oraz preparatu bitumicznego. Jako substancji agresywnych (korodotwórczych) użyto roztworów: kwasu etanowego, zasady amonowej, siarczanu VI sodu. Określono wpływ tych substancji na zmianą nasiąkliwości i ściśliwości badanych materiałów. Miarą nasiąkliwości była zmiana wilgotności materiałów podczas procesu wilgotnego składowania. Ściśli- wość obliczano na podstawie pomiarów deasymetrycznych: gęstości nasypowej swobodnej i upako- wanej, oznaczanych za pomocą cylindra miarowego. Niewielkie zmiany wartości współczynników ściśliwości uzyskane dla materiałów skorodowanych w porównaniu do wartości uzyskanych dla materiałów wyjściowych świadczą o podobnych właściwościach kohezyjnych obu rodzajów mate- riałów. Większość modyfikowanych (hydrofobowych) materiałów po procesie korodowania uzyski- wała gorsze właściwości wodoodporne niż materiały wyjściowe, ale w dalszym ciągu charakte- ryzowała sią wyższym stopniem hydrofobowości niż skorodowane materiały surowe. Dla mączki wapiennej nie uzyskano powtarzalnych wyników, co najprawdopodobniej spowodowane jest większą reaktywnością tego materiału związaną z małą średnicą ziaren. Przeprowadzone badania miały charakter wstępny.
Analiza porównawcza kosztu kapitału własnego przedsiębiorstw górnictwa węgła kamiennego w ujęciu międzynarodowym / Comparative Analysis of the Cost of Equity of Hard Coal Mining Enterprises – An International Perspective
Authors: Michalak Aneta , Leszek Nawrocki Tomasz 
Published: June 2015

Streszczenie
Branża górnictwa węgla kamiennego, uznawana za znajdującą się w fazie schyłkowej, przechodzi Ropniowe odrodzenie. Światowy rynek węgla rośnie. Popyt na czarne paliwo jest napędzany głównie przez energetykę w krajach spoza OECD oraz rosnące ceny alternatywnych nośników energii. W związku z rosnącą rolą przedsiębiorstw górniczych w rozwoju gospodarki światowej w niniejszym artykule podjęto problem kosztu kapitału własnego zaangażowanego w finansowanie tego typu przedsiębiorstw. Celem artykułu jest analiza porównawcza kosztu kapitału własnego przedsiębiorstw górniczych w ujęciu międzynarodowym. Zbadano koszt kapitału własnego w największych kon­cernach górniczych działających na rynku w Australii, Chinach oraz USA. Badaniem objęto 12 przed­siębiorstw wydobywających węgiel kamienny. Okres badań obejmuje lata 2009-2013. W badaniach zastosowano przede wszystkim analizę statystyczną danych pierwotnych, dotyczących notowań akcji badanych przedsiębiorstw górniczych oraz indeksów giełd papierów wartościowych, stanowiących dla nich benchmarki. Przeprowadzone badania mogą być pomocne do określenia perspektyw roz­wojowych węgla kamiennego na świecie w aspekcie uwarunkowań międzynarodowych. Pozwalają również uzyskać odpowiedź na podstawowe pytanie badawcze: czy w obliczu globalizacji rynków międzynarodowych i intensyfikacji przepływu surowców, w szczególności węgla, koszt kapitału własnego zaangażowanego do finansowania przedsiębiorstwa wydobywającego węgiel kamienny jest zróżnicowany względem rynku, na którym to przedsiębiorstwo działa? Uzyskane wyniki pozwalają stwierdzić, że koszt kapitału własnego przedsiębiorstw górnictwa węgla kamiennego jest zróż­nicowany w zależności od rynku, na którym te przedsiębiorstwa prowadzą działalność. Zaobser­wowana prawidłowość stanowi przyczynek dalszych badań w kierunku poszukiwania przyczyn tego zróżnicowania oraz wskazania konsekwencji w dłuższej perspektywie czasowej.