bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mitochondrial DNA depletion syndrome, type 3 (hepatocerebral type): a case report
Authors: Kalyakova Natalya V. , Shestak Evgenii V. , Krohaleva Yaroslava M. 
Published: July 2024

Backdround. Mitochondrial DNA depletion syndrome (MDDS) hepatocerebral type is an inherited disease that is inherited in an autosomal recessive type and is associated with a malfunction of the mitochondria. Progressive impairment of vital functions, metabolic and coagulation disorders characteristic of this disease, most often lead to death. At the moment, there is no pathogenetic treatment.Case report. A child born at 39 weeks of gestation from a closely related marriage had metabolic acidosis, hypoglycemia, hemorrhagic syndrome with acute liver failure from the first day of life, which subsequently led to death at the age of 17 days of life.Conclusion. The main clinical and laboratory signs are described, on the basis of which the presence of mtDNA depletion syndrome can be assumed. A molecular genetic examination has been carried out, which makes it possible to diagnose this disease in a child with a high probability and will give parents the opportunity for further more thorough examination, prenatal counseling and planning of the next pregnancy .
Ten-year cardiovascular risk estimation in type 2 diabetes in Europe using the novel SCORE2-Diabetes model
Authors: Arabidze G. G. , Mamedov M. N. , Akhundova H. R. 
Published: July 2024

The article presents a validated prognostic score (SCORE2-Diabetes) developed by a group of European researchers in collaboration with the European Society of Cardiology (ESC) for 10-year cardiovascular risk in type 2 diabetes (T2D) in Europe. The SCORE2-Diabetes risk calculator was developed based on the SCORE2 algorithms using data from patients with T2D and no prior cardiovascular disease (CVD). The authors developed a novel risk model that takes into account sex, age, age at diagnosis of T2D, glycated hemoglobin level, estimated glomerular filtration rate, smoking, systolic blood pressure, total cholesterol and high-density lipoprotein cholesterol levels, based on cardiovascular morbidity rate in 4 regions of Europe. The model included 38602 cases of CVD and showed good discrimination and calculation improvement compared to SCORE2 (change in C-index from 0,009 to 0,031) depending on the T2D-related factors. The authors consider adaptation of the SCORE2-Diabetes risk model to modern populations, including in the Russian Federation. Comparative analysis with similar models, assessing the advantages and disadvantages of various CVD risk models in patients with T2D is presented.Conclusion. SCORE2-Diabetes improves the identification of in­dividuals at higher cardiovascular risk in Europe based on new validated data from the European region.
An Earthquake Ground-Motion Model for Southwest Iberia
Authors: Taherian Amir , Silva Vitor , Kalakonas Petros , Vicente Romeu 
Published: July 2024

ABSTRACT
Ground-motion models (GMMs) are fundamental for the estimation of ground shaking for probabilistic seismic hazard assessment. Because of the paucity of ground motion recordings in regions of low seismicity, stochastic approaches are often employed to generate synthetic data. In this study, we developed a GMM using a stochastic simulation approach for southwest Iberia—a zone for which seismic hazard is usually assessed using models developed for other regions. We collected geological, tectonic, and ground-motion data for offshore and inland Iberia, and calibrated several parameters for a stochastic simulation. The resulting synthetic response spectra were used to train a machine learning algorithm (artificial neural network) capable of predicting peak ground acceleration, peak ground velocity, and spectral acceleration on rock (VS30=760  m/s), along with the associated between-event and within-event terms. The resulting model was compared against other existing models for stable continental regions and ground-motion recordings for Portugal and Spain. The results indicate a good agreement with observations and the model can be used directly in probabilistic seismic hazard analysis for southwest Iberia.
Deskripsi kemampuan siswa dalam menyelesaikan soal PISA
Authors: Asdamayanti Nurul , Putra Aan , Anggraini Reri Seprina 
Published: July 2024

Rendahnya hasil PISA diharapkan mampu memuat konten penting kemmapuan matematis yang dikembangkan dalam diri siswa dalam menyelesaikan soal-soal bertipe PISA. Tujuan dari penelitian ini adalah untuk mendeskripsikan kemampuan siswa dalam menyelesaikan soal PISA dengan menggunakan konten ruang dan bentuk. Metode penelitian ini adalah penelitian kuantitatif. Pengumpulan data kemampuan komunikasi matematis siswa menggunakan instrumen tes dan dokumentasi. Instrumen tes yang digunakan yaitu soal tes bentuk deskripsi dengan 4 buah butir soal dari level 1 sampai 4. Subjek penelitian ini adalah 24 siswa kelas VIII D SMPN 2 Sungai Penuh. Hasil penelitian diperoleh dengan menguji kemampuan matematis siswa SMP dalam menyelsaikan soal PISA materi Geometri pada materi bentuk dan bentuk, ditemukan bahwa hasil tes menunjukkan nilai rata-rata sebesar 34,33. Terdapat juga siswa yang tidak menjawab soal dan siswa dengan nilai maksimal 69. Standar deviasi yang diperoleh sebesar 15,07 persen, yang menunjukkan kategori rendah. Hasil penelitian juga menunjukkan bahwa 62,5 persen siswa termasuk dalam kategori rendah, 37,5 persen siswa dalam kategori sedang, dan tidak ada siswa yang termasuk dalam kategori tinggi. Dalam penelitian ini, siswa terutama berada pada level 1 dan 2, dengan proporsi siswa yang beberapa mampu menerapkan prosedur matematika dalam menyelesaikan masalah. Rekomendasi untuk penelitian analisis selanjutnya adalah kesalahan dan strategi siswa dalam menyelesaikan soal PISA.
IMPLEMENTASI MESIN COPER DENGAN SISTEM KERJA GANDA (COPER TURBO) UNTUK MASYARAKAT PETERNAK SAPI DESA SRIGONCO, BANTUR, KAB. MALANG
Authors: Edy Duwi Leksono , Ansyorie Musthofa Al , Marsono Marsono 
Published: July 2024

Desa Srigonco adalah sebuah desa yang subur dan asri yang terletak di Kecamatan Bantur, Kabupaten Malang, Jawa Timur. Desa Srigonco juga memiliki pantai sangat eksotis dan menarik wisatawan dari berbagai daerah bahkan wisatawan asing, pantai tersebut adalah Pantai Balekambang yang juga menjadi salah satu ikon kota dingin Malang. Masyarakat desa Srigonco memiliki mata pencaharian sebagian besar sebagai petani dan peternak sapi perah. Permasalahan yang dihadapi masyarakat srigonco dalam ternak sapi antara lain: 1) Bagaimana cara peningkatan produktifvitas bagi masyarakat peternak sapi desa srigonco Kec. Bantur, 2) Bagaimana meningkatkan perekonomian masyarakat peternak sapi desa srigonco bantur melalui pengolahan makanan ternak guna peningkatan hasil produksi sapi ternak. Solusi permasalahan yang dihadapi mitra antara lain: 1) Penerapan inovasi teknologi mesin Coper Turbo (mesin pencacah dengan system kerja ganda), 2)Pembuatan SOP komposisi makanan ternak sapi yang memiliki gizi bagus. Target luaran dari kegiatan ini 1) Inovasi teknologi Mesin Coper Turbo (mesin pencacah dengan system kerja ganda), 2) SOP komposisi makanan ternak sapi. Hasil dari kegiatan PKM dimana masyarakat UMKM peternak sapi di Desa Srigonco lebih efektif dalam pengelolaan pakan ternak.Kata Kunci: Mesin Cooper, UMKM, Desa Srigonco
PERANCANGAN MEROTAPALE (MESIN ROTARI OTOMATIS TABUR PAKAN LELE) MENGGUNAKAN RTC (REAL TIME CLOCK) BERBASIS ARDUINO MEGA 2560 UNTUK PENINGKATAN EFISIENSI DAN KUALITAS PRODUK BAGI KELOMPOK PETERNAK LELE DI KECAMATAN PAKIS KABUPATEN MALANG
Authors: Nauri Imam Muda , Sudjono Imam , Mindarta Erwin Komara 
Published: July 2024

Kebutuhan pasar terhadap komoditi ikan lele terus meningkat seiring dengan bertambahnya obyek wisata dan kuliner di Malang Raya. Dua hal yang menyebabkan empat dari sebelas anggota kelompok ternak ikan lele/arwana yang ada di RT 05 / RW 04 Desa Banjarejo, Kabupaten Malang, yang mengalami penurunan produksi hingga 15% dari tahun 2022 yakni akibat pemberian pakan lele yang tidak tepat waktu, dan pola penaburan pakan yang tidak merata. Dampak riil akibat hal ini adalah munculnya sifat kanibalis dan tidak meratanya pertumbuhan ikan lele yang berdampak sangat merugikan. Tujuan dari pengabdian ini adalah memberikan solusi atas masalah yang menyebabkan kerugian tersebut, agar tidak terus terjadi, secara meluas yakni melalui penggunaan alat yang didisain bekerja secara elektronik yang terkontrol berbasis pada pewaktuan yang riil, dan pola penaburan pakan dengan system rotary yang juga terkontrol. Komponen utama untuk membangun unit alat ini adalah real time clock (RTC) dan arduino Mega 2560 sebagai control unit , dan beberapa rangkaian elektronik lainnya yang menjadi system terintegrasi untuk menjamin waktu pemberian pakan tepat dan kontinyu, jumlah pakan yang terukur secara tepat serta pola taburan yang merata. Alat yang dirancang ini dapat menjangkau kolam yang berdimensi 20 x 20 m2 . Hasil dari alat yang dirancang ini adalah: dapat bekerja secara optimal dan otomatis, sehingga pemilik usaha memiliki sejumlah waktu yang dapat dimanfaatkan untuk pengembangan usaha laiannya. Biaya untuk melakukan pekerjaan rutin, dengan menggunakan alat ini tidak lagi ada. Perawatan alat ini sangat mudah dan sederhana. Pengisia tabung pakan cukup dilakukan sepekan sekali. Biaya listrik untuk beroperasinya alat ini sangat murah. Kata Kunci: Mesin penabur, Real time clock, Arduino mega
TEKNIK BUDIDAYA CABE KERITING SECARA ORGANIK DI KELOMPOK TANI HANDAYANI, PEKON SIDOKATON, KECAMATAN GISTING
Authors: Prajaka Nanang Wahyu , Kartina Raida , Putri Sekar Utami , Darma Wika Anrya , Jumawati Riana 
Published: July 2024

Pengabdian kepada masyarakat ini bertujuan untuk membimbing kelompok tani cabe khususnya kelompok tani Handayani untuk memulai membudidayakan tanaman cabe secara organik pada lahan usaha taninya. Metode pelaksanaan yang digunakan terdapat tiga tahapan yaitu peningkatan pengetahuan, peningkatan ketrampilan dan evaluasi. Peningkatan pengatahuan diberikan melalui ceramah untuk memberi pengetahuan tentang budidaya tanaman cabe organik, pestisida nabati dan pembuatan pupuk kompos berbahan Azolla pinnata; dilanjutkan peningkatan keterampilan dengan pembuatan pestisida nabati, perbanyakan Azolla pinnata dan pembuatan kompos, demplot tanaman cabe kemudian evaluasi. Bimbingan demonstrasi cara pembudidayaan cabe organik dimulai dari penanaman bibit di bumbungan, aplikasi kompos azolla pada lubang tanam, lalu penanaman cabe dan aplikasi pestisida nabati. Petani menanam cabe pada bedengan yang telah dibuat sebanyak 192 tanaman yang terbagi dalam 6 bedengan. Kemudian dilaksanakan kegiatan pemeliharaan, pengendalian hama dan penyakit dengan aplikasi pestisida nabati, dan panen serta penanganan pasca panen. Kegiatan ini akan dimonitor. Monitoring dilakukan 1 bulan sekali terutama di setiap akhir kelompok kegiatan budidaya yang dipraktikkan. Sebagai indikator keberhasilan adalah hasil evaluasi akhir penyuluhan dengan masing-masing indikator penilaian meningkat sebesar 90 persen dari segi pengetahuan budidaya cabe secara organik dan keterampilan teknik budidaya cabe organik meningkat.
The Role of Agroforestry in Ecosystem Services and Mitigation of Climate Change
Authors: Worku A. 
Published: July 2024

Relevance. Agroforestry systems are believed to provide a multitude of ecological services. It is thought that agroforestry enhances resilience to the impacts of climate change and aids in adaptation by supporting diverse land use practices, sustainable lifestyles, and income streams, as well as increasing productivity in both forests and agriculture, and reducing weather-related losses in production.Results and Discussion. The aim of this review was to present genuine evidence on the role of agroforestry in ecosystem conservation and mitigation of climate change impacts. Compared to monocropping and open cereal-based agriculture, agroforestry has made a more significant contribution to ecosystem conservation and in reducing carbon dioxide emissions. However, it has been found that agroforestry contributes less to carbon sequestration than natural forests. Carbon sequestration through above-ground and underground biomass, carbon emission reduction from deforestation, and microclimate adjustment are key measures for mitigating climate change. Agroforestry systems provide essential ecosystem services, such as food, fuel wood, fodder, income, and improved soil production, which enable communities to cope better with the impacts of climate change. Therefore, agroforestry must be given significant attention if it is to play a crucial role in ecosystem management.
Protection plants of cucumber (Cucumis sativus) based on the biological characteristics of the development of bacteriosis
Authors: Shishkina E. V. , Oderova E. V. 
Published: July 2024

Relevance. Large differences in the climatic conditions by the region Altai by years determine the prevalence and harmfulness of diseases, therefore, monitoring by the dynamics of disease development and assessing their harmfulness are relevant and necessary measures. An important role in modern plant protection technologies against diseases play biofungicides. The main advantages of biofungicides as compared with chemical plant protection products are safety for humans and the environment, short waiting times and the possibility of use throughout the growing season, the absence by risks of the emergence of resistant pathogens, the creation of conditions for the natural self–regulation of agrocenoses.Materials and Methods. The research was carried out in 2018-2020 on the fields of the West Siberian Vegetable Experimental Station of the branch of the West-Siberian vegetable experimental station – branch of the Federal State Budgetary Scientific Institution «Federal Scientific Vegetable Center». In the experiment was used the F1 hybrid Nezhinsky of Siberia. Accounting of the phytosanitary condition of crops were carried out in three periods with the determination by the degree of spread and the degree of development of the disease. Studied were the doses and timing of the use of biological preparations Phytolavin and Phytoplasmin in the fight against cucumber bacteriosis during the growing season. The repeatability of the experience was 4-fold, the placement of plots in 4 tiers, the area of the plot was 10 m2 , the accounting area was 3 m2 . The total area were 0.05 hectares.Results. The applicationof drugs Phytolavin (2 l/ha), Phytoplasmin (3 l/ha), promotes to reduce the pace of development of development of bacterial spotting of cucumber in the open ground. The least development of the disease was noted by using the drugs Phytolavin 2 l/ha, Phytoplasmin 3 l/ha, Phytolavin 2 l/ha, with alternation and an interval of 14 days. By the influence of bactericidal treatments against bacterial spotting of cucumber, a higher weight of seed fruits was obtained in all variants compared to the control. The best result – 11.96% to the control was obtained on the variant by using the preparations Phytolavin 2 l/ha, Phytoplasmin 3 l/ha with alternation.
Diagnostics of mineral nutrition of carrot and red beet at organic and mineral fertilization systems
Authors: Belova S. V. 
Published: July 2024

Relevance. In the transition to highly productive and environmentally friendly, in particular, organic agriculture and production of safe and high-quality products, which is a priority direction of strategies of scientific and technological development of the Russian Federation, one of the necessary links is the creation and control of optimal conditions of plant nutrition, i.e. provision of plants with nutrients in the right combination throughout the vegetation. Achievement of such conditions is possible through soil and plant nutrition diagnostics, which in turn allows to establish the ability of crops to assimilate nutrients from the soil and adjust the doses of mineral fertilisers as top dressings.Material and Methods. On alluvial meadow soil in the conditions of the non-Black Earth region of Russia, the effectiveness of root feeding with macronutrients (NPK) was studied according to the results of plant and soil diagnostics of table root crops nutrition when grown on organic and mineral fertiliser systems. Plant and soil diagnostics of mineral nutrition was carried out according to the methods of Zerling V.V. (1990) and Magnitsky K.P. (1972). Two crops were tested during the experiment: red beet variety Mulatka and garden carrot variety Losinoostrovskaya 13.Results and Discussion. Root fertilizers on the basis of nutrition diagnostics on the basis of soil and leaf petiole analysis made significant changes in the dynamics of basic nutrients in the soil, there was an increase in nitrate nitrogen and mobile potassium in comparison with the control variant, with natural soil supply of mobile phosphorus (more than 250 mg/kg), which had a positive effect on the root nutrition of plants. At the main application of mineral and organic (biocompost BIUD) fertilizers, root fertilizers according to nutrition diagnostics the carrot yield 51,2-63,9 t/ha with standard 87,4- 94,6%, red beet 41,7-54,2 t/ha with standard 80,7-92,3% were obtained. Root feeding of carrots by soil diagnostics N52K14 on the background of biocompost gave 24.9% increase to the control, by plant diagnostics N17 gave 16.6%; red beet by soil diagnostics N65K45 – 30% increase, by plant diagnostics N54K30 – 23.7%
Study of new elements of technology for cultivating a medium-ripening melon variety
Authors: Galichkina E. A. , Varivoda E. A. 
Published: July 2024

Relevance. Due to climate change on the planet, it is becoming increasingly difficult to obtain high yields of melons and melons in rain-fed conditions. Therefore, it is necessary to develop modern methods of growing them. Accordingly, the use of new water-soluble fertilizers for the cultivation of melon in hot climates is a relevant work at the moment.Material and methodology. Objects of research: medium-ripening melon variety GP 599f and watersoluble fertilizers Lignohumate, Energen Extra, Zinc Sulfate. We have carefully studied options using these fertilizers for double foliar treatment of plants during the growing season.Results. As a result of studying new types of water-soluble fertilizers on increasing the vegetative mass of plants, yield and biochemical parameters of the variety sample, a positive effect was revealed. As a result of a comparative analysis of data on plant development after double treatment with the studied preparations, an increase in canes in all variants was noted in relation to the control by 4.3-18.7%. When calculating the yield in all studied options, an increase in these indicators was noted in relation to the option without treatments. After treating the plants with new types of fertilizers, the yield was 13.4-15.9 t/ha. The average fetal weight varied from 1.7 kg. up to 1.8 kg with maximum values in the Lignohumate and Energen Extra options. An analysis of the comparison of the biochemical composition of fruits showed that new types of fertilizers did not affect the taste and purity of the products. The dry matter content was noted to be 0.8-1% higher than the control variant. Nitrate levels in fruits did not exceed the maximum permissible concentration (90 mg/kg) and amounted to 24-28 mg/kg.
Residential Proximity to Oil and Gas Development and Mental Health in a North American Preconception Cohort Study: 2013–2023
Authors: Willis Mary D. , Campbell Erin J. , Selbe Sophie , Koenig Martha R. , Gradus Jaimie L. , Nillni Yael I. , Casey Joan A. , Deziel Nicole C. , Hatch Elizabeth E. , Wesselink Amelia K. , Wise Lauren A. 
Published: July 2024

Objectives. To evaluate associations between oil and gas development (OGD) and mental health using cross-sectional data from a preconception cohort study, Pregnancy Study Online. Methods. We analyzed baseline data from a prospective cohort of US and Canadian women aged 21 to 45 years who were attempting conception without fertility treatment (2013–2023). We developed residential proximity measures for active OGD during preconception, including distance from nearest site. At baseline, participants completed validated scales for perceived stress (10-item Perceived Stress Scale, PSS) and depressive symptoms (Major Depression Inventory, MDI) and reported psychotropic medication use. We used log-binomial regression and restricted cubic splines to estimate prevalence ratios (PRs) and 95% confidence intervals (CIs). Results. Among 5725 participants across 37 states and provinces, residence at 2 km versus 20 to 50 km of active OGD was associated with moderate to high perceived stress (PSS ≥ 20 vs < 20: PR = 1.08; 95% CI = 0.98, 1.18), moderate to severe depressive symptoms (MDI ≥ 20 vs < 20: PR = 1.27; 95% CI = 1.11, 1.45), and psychotropic medication use (PR = 1.11; 95% CI = 0.97, 1.28). Conclusions. Among North American pregnancy planners, closer proximity to OGD was associated with adverse preconception mental health symptomatology. ( Am J Public Health. 2024;114(9):923–934. https://doi.org/10.2105/AJPH.2024.307730 )
Central Tendon Tenotomy for Management of Extrinsic Extensor Tightness of the Hand
Authors: Chughtai Morad , Parrish Ryan , Tabarestani Arman , Dougherty Courtney , Matthias Robert C. , Dell Paul C. 
Published: July 2024

Case:
We present a 67-year-old woman with long finger extrinsic extensor tightness and a 56-year-old man with limited index finger flexion due to extrinsic extensor tightness secondary to tendon transfers for radial nerve palsy. Both patients underwent prior surgical procedures that led to limited range of motion (ROM). Subsequently, they elected for central tendon tenotomy (CTT), which demonstrated postoperative ROM improvement and satisfactory patient outcomes.

Conclusion:
Surgical management of extrinsic extensor tendon tightness of the hand is generally addressed by performing tenolysis to improve tendon excursion. We present a novel and simple technique of CTT with pertinent anatomy, descriptive cases, and a cadaveric video.
Machine Learning–Assisted Decision Making in Orthopaedic Oncology
Authors: Rizk Paul A. , Gonzalez Marcos R. , Galoaa Bishoy M. , Girgis Andrew G. , Van Der Linden Lotte , Chang Connie Y. , Lozano-Calderon Santiago A. 
Published: July 2024

» Artificial intelligence is an umbrella term for computational calculations that are designed to mimic human intelligence and problem-solving capabilities, although in the future, this may become an incomplete definition. Machine learning (ML) encompasses the development of algorithms or predictive models that generate outputs without explicit instructions, assisting in clinical predictions based on large data sets. Deep learning is a subset of ML that utilizes layers of networks that use various inter-relational connections to define and generalize data.» ML algorithms can enhance radiomics techniques for improved image evaluation and diagnosis. While ML shows promise with the advent of radiomics, there are still obstacles to overcome.» Several calculators leveraging ML algorithms have been developed to predict survival in primary sarcomas and metastatic bone disease utilizing patient-specific data. While these models often report exceptionally accurate performance, it is crucial to evaluate their robustness using standardized guidelines.» While increased computing power suggests continuous improvement of ML algorithms, these advancements must be balanced against challenges such as diversifying data, addressing ethical concerns, and enhancing model interpretability.