bluuebunny/crossref_metadata_2025_split huggingface dataset:
Negative and positive life events are associated with small but lasting change in neuroticism
Authors: Jeronimus B. F. , Ormel J. , Aleman A. , Penninx B. W. J. H. , Riese H. 
Published: February 2013

BackgroundHigh neuroticism is prospectively associated with psychopathology and physical health. However, within-subject changes in neuroticism due to life experiences (LEs) or state effects of current psychopathology are largely unexplored. In this 2-year follow-up study, four hypotheses were tested: (1) positive LEs (PLEs) decrease and negative LEs (NLEs) increase neuroticism; (2) LE-driven change in neuroticism is partly long-lasting; and (3) partly independent of LE-driven changes in anxiety/depression; and (4) childhood adversity (before age 16 years) moderates the influence of NLEs/PLEs on neuroticism scores in adult life.MethodData came from the Netherlands Study of Depression and Anxiety [NESDA, n = 2981, mean age 41.99 years (s.d. = 13.08), 66.6% women]. At follow-up (T2) we assessed PLEs/NLEs with the List of Threatening Experiences (LTE) over the prior 24 months and categorized them over recent and distant PLE/NLE measures (1–3 and 4–24 months prior to T2 respectively) to distinguish distant NLE/PLE-driven change in trait neuroticism (using the Dutch version of the Neuroticism–Extroversion–Openness Five Factor Inventory, NEO-FFI) from state deviations due to changes in symptoms of depression (self-rated version of the 30-item Inventory of Depressive Symptomatology, IDS-SR30) and anxiety (Beck Anxiety Inventory, BAI).ResultsDistant NLEs were associated with higher and distant PLEs with lower neuroticism scores. The effects of distant LEs were weak but long-lasting, especially for distant PLEs. Distant NLE-driven change in neuroticism was associated with change in symptoms of anxiety/depression whereas the effect of distant PLEs on neuroticism was independent of any such changes. Childhood adversity weakened the impact of distant NLEs but enhanced the impact of distant PLEs on neuroticism.ConclusionsDistant PLEs are associated with small but long-lasting decreases in neuroticism regardless of changes in symptom levels of anxiety/depression. Long-lasting increases in neuroticism associated with distant NLEs are mediated by anxiety/depression.
Regulation of cholinergic activity by the vesicular acetylcholine transporter
Authors: Prado Vania F. , Roy Ashbeel , Kolisnyk Benjamin , Gros Robert , Prado Marco A. M. 
Published: February 2013

Acetylcholine, the first chemical to be identified as a neurotransmitter, is packed in synaptic vesicles by the activity of VAChT (vesicular acetylcholine transporter). A decrease in VAChT expression has been reported in a number of diseases, and this has consequences for the amount of acetylcholine loaded in synaptic vesicles as well as for neurotransmitter release. Several genetically modified mice targeting the VAChT gene have been generated, providing novel models to understand how changes in VAChT affect transmitter release. A surprising finding is that most cholinergic neurons in the brain also can express a second type of vesicular neurotransmitter transporter that allows these neurons to secrete two distinct neurotransmitters. Thus a given neuron can use two neurotransmitters to regulate different physiological functions. In addition, recent data indicate that non-neuronal cells can also express the machinery used to synthesize and release acetylcholine. Some of these cells rely on VAChT to secrete acetylcholine with potential physiological consequences in the periphery. Hence novel functions for the oldest neurotransmitter known are emerging with the potential to provide new targets for the treatment of several pathological conditions.
CMOS 45 GHz vector modulator with gain/phase correction through calibration
Authors: Juntunen E. , Dawn D. , Laskar J. , Papapolymerou J. 
Published: February 2013

A 45 GHz vector modulator designed in 45 nm SOI CMOS is presented along with an open‐loop calibration technique for gain/phase correction. The continuous 360° vector modulator consists of a passive quadrature signal generation network followed by a Gilbert cell modulator. The simple, open‐loop calibration procedure results in RMS gain and phase errors less than 0.5 dB and 5°, respectively. The circuit consumes 18 mW of DC power from a 1 V supply.
60 GHz CMOS downconversion mixer with 15.46 dB gain and 64.7 dB LO‐RF isolation
Authors: Lee J.H. , Lin Y.S. 
Published: February 2013

A 60 GHz double‐balanced mixer for direct downconversion using standard 90 nm CMOS technology is reported. The downconversion mixer comprises a double‐balanced Gilbert cell with a current‐reused RF single‐to‐differential converter for conversion gain (CG) enhancement, a Marchand balun for converting the single LO input signal to a differential signal, and a baseband amplifier. The mixer consumes 17 mW and achieves a low noise figure of 12.8 dB at 60 GHz. In addition, the mixer achieves excellent LO‐RF isolation of 64.7 dB, LO‐IF isolation of 51.5 dB, and RF‐IF isolation of 59.5 dB at an RF of 60 GHz and LO of 59.9 GHz. At IF of 0.1 GHz, the mixer achieves maximum CG of 15.46 dB at an RF of 62 GHz, and CG of 14.7 dB at an RF of 60 GHz, which are believed to be the best CG results ever reported for a 60 GHz active CMOS downconversion mixer.
Balanced pulse generator for ultra‐wideband radar application
Authors: Xia Xinfan , Liu Lihua , Guan Hongfei , Fang Guangyou 
Published: February 2013

A balanced pulse generator with high voltage amplitude and pulse width in the picoseconds region is described. It can operate well at the pulse repetition frequency (PRF) up to 500 kHz. The proposed generator contains four NPN silicon power transistors operating in avalanche mode and a pair of pulse shaping circuits which effectively utilise the transition characteristics of a step recovery diode. Measurement results are presented, which show the output of the generator are balanced pulses with peak values of ±46 V at 100 kHz PRF and approximately 330 ps full‐width at half‐maximum in width.
Taxonomy and botany.
Authors: Chanderbali A. S. , Soltis D. E. , Soltis P. S. , Wolstenholme B. N. 
Published: February 2013

Abstract

This chapter focuses on taxonomy of the genus Persea, including keys to the species. The gross morphology, architecture and growth habit of the cultivated avocado tree is also discussed as a basis for a better understanding of tree management and manipulation.
Ecology: climate and soils.
Authors: Wolstenholme B. N. 
Published: February 2013

Abstract

This chapter gives an overview of climatic and soil variables that determine where various types of avocados can be successfully grown. The importance of stress minimization of stress to achieve commercial viability, climate and soil selection and Phytophthora root rot resistance are discussed and the risks posed by high rain hazards and less than adequately drained soils to the long-term viability of avocado orchards are presented.
Insect and mite pests.
Authors: Peña J. E. , Hoddle M. S. , Aluja M. , Palevsky E. , Ripa R. , Wysoki M. 
Published: February 2013

Abstract

Insect and mite pests. This chapter describes the most common pests of avocado in different growing areas of the world. Some current pest management methodologies are also presented..
Harvesting, packing, postharvest technology, transport and processing.
Authors: Hofman P. J. , Bower J. , Woolf A. 
Published: February 2013

Abstract

This chapter provides updated information on avocado fruit quality parameters, sensory perception and maturity, production and postharvest factors affecting quality defects, disinfestation and storage (including pre-conditioning), predicting outturn quality and processing.
A systematic review of the literature on counselling and psychotherapy for the prevention of suicide: 1. Quantitative outcome and process studies
Authors: Winter David , Bradshaw Siobhan , Bunn Frances , Wellsted David 
Published: February 2013

AbstractScope of review: The paper reports a meta‐review of 15 previous systematic reviews and meta‐analyses of the literature concerning the outcome of counselling and psychotherapy with people at risk of suicide; a meta‐analysis of 67 outcome studies in this area; and a narrative review of 17 studies of the therapeutic process. Publication time span: The literature reviewed was published between 1981 and 2008. Publication origin: The majority of the literature reviewed was by authors from the USA or the UK, but there were also authors from other European countries, Australia, Canada, India, and Sri Lanka. Findings: There is evidence of the effectiveness of dialectical behaviour therapy, cognitive‐behavioural therapy, and problem solving therapy, but also for other forms of therapy. Therapist and client variables, as well as the therapeutic relationship, appear to be related to treatment outcome. Conclusions: People at risk of suicide should have access to psychological interventions, including, but not necessarily limited to, those within the cognitive‐behavioural spectrum. Therapies for which there have been promising findings, but which are under‐researched, should be a research priority.
Transcriptome signature in young children with acute otitis media due to non-typeable Haemophilus influenzae
Authors: Liu Keyi , Chen Linlin , Kaur Ravinder , Pichichero Michael E. 
Published: February 2013

Abstract
Non-typeable Haemophilus influenzae (NTHi) causes acute otitis media (AOM) in young children. In our recent paper in Microbes and Infection we described the transcriptome signature elicited from PBMCs at onset of AOM caused by Streptococcus pneumoniae. In the current study we found very different results with NTHi AOM infections; 5.1% of 29 187 genes were differentially regulated by more than 2-fold at the onset of AOM compared with the pre-infection healthy state in the same children. Among the 1487 transcripts, 100 genes associated with the immune defense response were specifically analyzed. About half of the differentially regulated genes associated with antibacterial activity and the cell-mediated immune response were activated and half were suppressed. The important signatures for NTHi in children suggested that the balance of the immune response was toward suppression. Moreover, 90% of the genes associated with a pro-inflammatory cytokine response were down-regulated. The genes associated with the classic complement pathway were down-regulated, although the alternative complement pathway genes were up-regulated. These results provide the first human transcriptome data identifying gene expression in the immune response to be predominantly down-regulated at the onset of AOM due to NTHi.
Identification of a Dual-Targeted Protein Belonging to the Mitochondrial Carrier Family That Is Required for Early Leaf Development in Rice
Authors: Xu Jiming , Yang Jian , Wu Zhongchang , Liu Huili , Huang Fangliang , Wu Yunrong , Carrie Chris , Narsai Reena , Murcha Monika , Whelan James , Wu Ping 
Published: February 2013

Abstract
A dual-targeted protein belonging to the mitochondrial carrier family was characterized in rice (Oryza sativa) and designated 3′-Phosphoadenosine 5′-Phosphosulfate Transporter1 (PAPST1). The papst1 mutant plants showed a defect in thylakoid development, resulting in leaf chlorosis at an early leaf developmental stage, while normal leaf development was restored 4 to 6 d after leaf emergence. OsPAPST1 is highly expressed in young leaves and roots, while the expression is reduced in mature leaves, in line with the recovery of chloroplast development seen in the older leaves of papst1 mutant plants. OsPAPST1 is located on the outer mitochondrial membrane and chloroplast envelope. Whole-genome transcriptomic analysis reveals reduced expression of genes encoding photosynthetic components (light reactions) in papst1 mutant plants. In addition, sulfur metabolism is also perturbed in papst1 plants, and it was seen that PAPST1 can act as a nucleotide transporter when expressed in Escherichia coli that can be inhibited significantly by 3′-phosphoadenosine 5′-phosphosulfate. Given these findings, together with the altered phenotype seen only when leaves are first exposed to light, it is proposed that PAPST1 may act as a 3′-phosphoadenosine 5′-phosphosulfate carrier that has been shown to act as a retrograde signal between chloroplasts and the nucleus.
Burden of multiple disabilities among the older population in India
Authors: Maikho Apollo Pou Ladumai , Goli Srinivas 
Published: February 2013

PurposeThe aim of this study is twofold, first, to estimate the prevalence of multiple disabilities among the older population in India; second, to examine the socio economic determinants of multiple disabilities among the older population.Design/methodology/approachThis study used the India Human Development Survey Data (IHDS) for the analysis. Bivariate, multinomial logit regression and multiple classification analysis are used as methods for the study. Disability score is constructed for measuring the multiple disabilities among the older population.FindingsThe results of disability prevalence show, a high prevalence of multiple disabilities among the older population in India. Further, disability prevalence varies considerably by age and socio‐economic characteristics of the older population. Among all the socioeconomic factors, economic factor emerged as a dominant predictor of prevalence of disabilities among the older population in India. The findings of the dimension specific assessment reveal that the disability in walking is the highest among all the disabilities. The distribution of disabled older population by living arrangement and the social network indicates that a large proportion of disabled older population lives with their children. In addition, only a few of the disabled older people have social networks. The distribution of disabled older people by employment and financial source reveal that there is a meager government support to the disabled older population in India. This study evidently suggests that a significant number of older populations in India are suffering from multiple disabilities. The number of multiple disabilities increases with the decrease in the socioeconomic status. The living arrangement and financial security assessment suggest that there is an increasing need of children and government support to the disabled older population.Originality/valueThe distinctiveness of this study can be primarily found in the type of the data used, the assessment of additional disability dimensions, and the inclusion of differentials such as living arrangement, social network and work status as part of the analysis. Overall, the study with its robust statistical assessment provides a number of key insights into the social, economic security, and health care needs of the disabled older population in India.
Steel supply chain management by simulation modelling
Authors: Sandhu Maqsood Ahmad , Helo Petri , Kristianto Yohanes 
Published: February 2013

PurposeThe aim of this paper is to propose a simulation study of the “steel supply chain” to demonstrate the effect of inventory management and demand variety on the bullwhip effect mitigation.Design/methodology/approachThe relevant literature is reviewed, and then the simulation model proposed.FindingsThis study identifies reasons for sharing information under varying levels of demand and some variants, and demonstrates the benefits of mitigating the bullwhip effect by applying a design of experiment. It is shown that the information sharing is able to mitigate the bullwhip effect in the steel supply chain by extending the order interval and minimising the order batch size.Research limitations/implicationsThis study explores the factors associated with the bullwhip effect. This research is focused on built‐to‐order simulation, so the results are only oriented on the basis of orders; hence a simultaneous order‐ and forecast‐based steel supply chain should be carried out in the future.Practical implicationsThis framework is expected to provide a convenient way to measure the optimum inventory level against a limited level of demand uncertainty, and thus enterprises can promote the supply chain coordination.Originality/valueAn innovative simulation model of the “steel supply chain” is proposed, which includes information sharing in the simulation model. Furthermore, dynamic scheduling is shown by applying a continuous ordering and order prioritization rule to replace traditional scheduling methods.
The supplemental role of operating cash flows in explaining share returns
Authors: Agnes Cheng C.S. , Johnston Joseph , Zishang Liu Cathy 
Published: February 2013

PurposeIn response to recent concerns on earnings quality and a firm's fundamental performance, the purpose of this paper is to re‐examine salient questions under accrual accounting: how earnings quality affects the role of earnings and operating cash flows in a firm's valuation.Design/methodology/approachUsing a large sample ranging from 1989 to 2008, the authors contrast the effects of three representative accrual‐based earnings quality measures on the association between earnings, operating cash flows and a firm's abnormal stock returns.FindingsIn the univariate analysis it was found that earnings explain returns similarly to operating cash flows. With control of earnings quality, the results indicate that earnings' role in explaining contemporaneous abnormal returns remains unchanged when earnings quality is better. Conversely, operating cash flows explain more contemporaneous abnormal returns when earnings quality is better. The findings could suggest that the market reacts to operating cash flows conditionally on earnings quality. Intriguingly, the results also indicate that the market perceives better earnings quality captures superior performance of operating cash flows rather than that of earnings. These findings are further fortified by additional analyses revealing that the earnings quality measure with control of operating cash flows affects the supplemental role of operating cash flows most.Originality/valueThe paper's findings provide insights on how the market processes firm value signals embedded in earnings quality, which have direct implications for regulators, standard setters, academics and practitioners.
Petrogenesis of Cenozoic Basaltic Rocks from Jiangsu Province, China: Evidence from Geochemical Constraints
Authors: LEE Yung‐Tan , CHEN Ju‐Chin , SHIH Jyh‐Yi , HO Kung‐Suan , YANG Huai‐Jen , LIN Meng‐Lung , HU Yen‐Tsui , CHIU Ching‐Hsing 
Published: February 2013

AbstractCenozoic (Miocene to Pleistocene) basaltic rocks in Jiangsu province of eastern China include olivine tholeiite and alkali basalt. We present major, trace element and Sr‐Nd isotopic data as well as Ar‐Ar dating of these basalts to discuss the petrogenesis of the basalts and identify the geological processes beneath the study area. On the basis of chemical compisitions and Ar‐Ar dating of Cenonoic basaltic rocks from Jiangsu province, we suggest that these basalts may belong to the same magmatic system. The alkali basalts found in Jiangsu province have higher σFeO, MgO, CaO, Na2O, TiO2 and P2O5 and incompatible elements, but lower Al2O3 and compatible elements contents than olivine tholeiite which may be caused by fractional crystallization of olivine, pyroxene and minor plagioclase. In Jiangsu basaltic rocks the incompatible elements increase with decreasing MgO/σFeO ratios. The primitive mantle‐normalized incompatible elements and chondrite‐normalized REE patterns of basaltic rocks found in Jiangsu province are similar to those of OIB. Partial loss of the mantle Uthosphere accompanied by rising of asthenospheric mantle may accelerate the generation of the basaltic magma. The 143Nd/144Nd vs. 87Sr/86Sr plot indicates a mixing of a depleted asthenospheric mantle source and an EM1 component in the study area. According to Shaw's equation, the basalts from Jiangsu province may be formed by 1%–5% partial melting of a depleted asthenospheric mantle source. On the basis of Ar‐Ar ages of this study and the fractional crystallization model proposed by Brooks and Nielsen (1982), we suggest that basalts from Jiangsu province may belong to a magmatic system with JF‐2 as the primitive magma which has undergone fractional crystallization and evolved progressively to produce other types of basalts.
Geochemical Characteristics and Genesis of the Metallogenic Rocks in the Chagande'ersi Molybdenum Deposit in Wulatehouqi, Inner Mongolia
Authors: Kai YAN , Rongge XIAO , Zhongyin HE , Gang FENG , Shuli WANG 
Published: February 2013

AbstractGeochemical characteristics of the Chagande'ersi molybdenum deposit in Inner Mongolia and its genesis were analyzed in this study using rock mineralography and rock geochemical testing. The mineralized country rocks of the Chagande'ersi molybdenum deposit consist mainly of medium‐to fine‐grained monzogranite, medium‐to fine‐grained rich‐K granite, with minor fine‐grained K‐feldspar granite veins and quartz veins. The rocks are characterized by high silica, rich alkali, high potassium, which are favorable factors for molybdenum mineralization. The rocks have the Rittmann index ranging from 1.329 to 1.961, an average Na2O+K2O value of 7.41, and Al2O3/(CaO+Na2O+K2O) >1, suggesting that the rocks belong to the high‐K calc‐alkaline peraluminous granite. The typical rock samples are enriched in Rb, Th, K and light rare earth elements, depleted in Sr, Ba, Nb, P and Ti, and these features are similar to that of the melt granite resulting from collision of plate margins. The δEu of the rocks falls the zone between the crust granite and crust‐mantle granite, and are close to that of the crust granite; (La/Lu)N indicates the formation environment of granite is a continental margin setting. The Nb/Ta ratios are close to that of the average crust (10); the Zr/Hf ratios of monzogranite are partly below the mean mantle (34–60), while the Zr/Hf ratio of K‐feldspar granite are close to the mean value in the crust Comprehensive analyses show that the granite in this area formed during the transition period between tectonic collision and post‐collision. During the plate collision and orogeny, the crust and mantle material were mixed physically, remelting into lava and then crystal fractionation, finally gave rise to the formation of the rock body in this area. This has close spatial and temporal relation with the molybdenum mineralization.