bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of social and environmental restrictions, and changes in alcohol availability in adolescents’ binge drinking during the COVID-19 pandemic
Authors: Rogés Judit , Bosque-Prous Marina , Folch Cinta , Teixidó-Compañó Ester , González-Casals Helena , Colom Joan , Lafon-Guasch Aina , Fortes-Muñoz Paula , Espelt Albert 
Published: August 2024

Aims
The aim of the present study was to estimate the evolution of binge drinking since the pre-pandemic period, and throughout the pandemic period with the application and lifting of the restrictions in adolescents aged 12 to 19 years old in school in Central Catalonia.

Methodology
Quasi-experimental time series study with two samples of adolescents. The first sample (1st wave of survey, pre-pandemic period) was obtained between the months of September 2019 to March 2020 (n = 6621) and the second sample (2nd wave of survey, pandemic period) between the months of October 2021 and March 2022 (n = 7576). The dependent variable was monthly binge drinking. The main independent variable was the period of data collection (1st and 2nd wave), and gender and grade were also included. Twenty-one time slices were performed by fortnight and the binge drinking prevalence of the previous month was extracted in each of them. Interrupted time series analysis was performed and Poisson regression models with robust variance were estimated.

Results
The data indicated a significant increase in the prevalence of binge drinking in certain periods in girls [easing of measures in October, aPR: 2.25 (1.03–4.89); and total lifting of restrictions in February, aPR: 3.29 (1.57–6.89)] and a reduction in consumption in periods of tightening of restrictions. After the upturn before the return to the pre-pandemic situation binge drinking followed a decreasing trend in both sexes [aPR boys: 0.73 (95%CI: 0.66–0.81); aPR girls: 0.78 (95%CI: 0.71–0.86)].

Conclusions
Periods of community interventions aimed at protecting people’s health have had an impact on other health behaviors or aspects of health such as binge drinking, and differentially across groups and communities.
The Efficacy of Topical Tranexamic Acid in Breast Surgery Evaluating The Drain Output and Complications Reduction: A Systematic Review and Meta-Analysis
Authors: Sudarman Jesica Putri , Sayudo Iqbal F. , Putri Marcelvina Mutiara , Ali Gary , Handini Nurliati Sari 
Published: August 2024

Introduction : The topical administration of Tranexamic Acid (TXA) has gained significant attention for its potential advantages in various plastic surgery procedures. This study aims to conduct a systematic review and meta-analysis focusing on the use of topical TXA in breast surgery, analysing its impact on postoperative drain output and complications.Method : PubMed, Embase and the Cochrane Library databases were systematically searched to identify relevant studies. The data synthesis utilized random-effects models and the findings were presented as a mean difference and weighted odds ratio along with the corresponding 95% confidence interval.Results : Seven studies including four RCTs and three observational studies, comprising 1,553 breasts undergoing surgery were included. The average age of participants was 46 years; mean body mass index (BMI) was 26.1 kg/mm2. Of the breasts studied, 764 (49%) received topical TXA and 789 (51%) received normal saline as placebo. Overall, topical TXA was associated with a lower drain output in the first 24 hours postoperative (MD -25.87; p=0.00001) and a lower cumulative drain output (MD -59.72; p<0.00001). The rate of hematoma is significantly lower in the topical TXA group compared to the control group (OR 0.19; p=0.0009). There were no significant differences in rates of seroma, infection, thromboembolic events and time to drain removal between groups. Conclusion: Evidence of this study suggests that administration of topical TXA significantly reduces the drain output production and hematoma in breast surgery. The use of topical TXA not significantly affecting rates of seroma, infection and postoperative duration with drain.
La seguridad alimentaria, ¿derecho humano garantizado?
Authors: Mettini Guadalupe , Rispolo Florencia Daniela , D´Angelo María Victoria , Narvaez Marcos , Fontanini Dámaris 
Published: August 2024

La seguridad alimentaria es actualmente, y desde hace un largo tiempo, un desafío a escala global cada vez más preocupante. Usualmente se asocia esta problemática con la escasez de alimentos, sin embargo, sus raíces e implicancias son bastante más amplias y complejas. De este modo, a pesar de ser reconocido como un derecho humano fundamental, su cumplimiento sigue siendo un problema sin resolver en muchas regiones, especialmente en países en desarrollo como el nuestro.
Abordar esta cuestión implica reflexionar sobre la oferta y distribución de alimentos, los factores económicos y sociales, desigualdad en el acceso a recursos, sistemas de producción, aspectos culturales, políticas y regulaciones inadecuadas y el impacto de la crisis ecológica, entre muchos otros. Esto significa que estudiar esta problemática supone, por un lado, reconocer la multiplicidad de aristas presentes y, por otro, intentar construir una mirada integral y multidimensional.
Este artículo se propone explorar los aspectos sociales y políticos de la seguridad alimentaria. De esta forma, el objeto del trabajo fue contribuir a la comprensión de la problemática de la seguridad alimentaria a nivel local y nacional, asumiendo la multidimensionalidad de este fenómeno. Para ello se realizó un breve recorrido histórico por la definición del concepto de seguridad alimentaria, se reconstruyó el estado de la cuestión a partir de estadísticas sobre las condiciones de alimentación de la población mundial y local y, finalmente, se reflexionó sobre los modelos productivos vigentes y el accionar estatal frente a este flagelo.
PENDAMPINGAN SERTIFIKASI HALAL KERUPUK RAMBAK KULIT DUSUN CEGOKAN DESA WONOLELO KABUPATEN BANTUL
Authors: Imelda Fajriati  , Diza Harris Pratiwi  , Abdul Aziz  , Prabawati Susy Yunita 
Published: August 2024

Assistance for halal certification for Micro Small Businesses of Wonolelo Bantul leather rambak crackers has been carried out in order to support the acceleration of halal product guarantees as mandated by Law No. 33 of 2014. Micro and small business actors (MSEs) are the largest producers of food and beverage products that are subject to mandatory halal because of the increasing number of MSE commodities. The assistance method is carried out by providing socialization and education carried out in groups and individually, followed by discussion and interpretation of the identification results during the assistance process. The results of the assistance obtained that10 business actors in Cegokan, Wonolelo Bantul who were assisted to obtain halal certificates generally met the criteria for halal product processes in accordance with the provisions of the SJPH (Halal Product Guarantee System). Business actors have understood and followed the provisions in applying for halal certification. However, rambak cracker products still have difficulty getting raw materials from halal-certified slaughterhouses. The supply of raw materials is temporarily obtained from collectors, making it relatively difficult to follow the principle of tracebelity.
Molecular surface coverage standards by reference-free GIXRF supporting SERS and SEIRA substrate benchmarking
Authors: Cara Eleonora , Hönicke Philipp , Kayser Yves , Beckhoff Burkhard , Giovannozzi Andrea M. , Klapetek Petr , Zoccante Alberto , Cossi Maurizio , Tay Li-Lin , Boarino Luca , Ferrarese Lupi Federico 
Published: August 2024

Abstract
Non-destructive reference-free grazing incidence X-ray fluorescence (RF-GIXRF) is proposed as a highly effective analytical technique for extracting molecular arrangement density in self-assembled monolayers. The establishment of surface density standards through RF-GIXRF impacts various applications, from calibrating laboratory XRF setups to expanding its applicability in materials science, particularly in surface coating scenarios with molecular assemblies. Accurate determination of coverage density is crucial for proper functionalization and interaction, such as in assessing the surface concentration of probes on plasmonic nanostructures. However, limited synchrotron radiation access hinders widespread use, prompting the need for molecular surface density standards, especially for benchmarking substrates for surface-enhanced Raman and infrared absorption spectroscopies (SERS and SEIRA) as well as associated surface-enhanced techniques. Using reproducible densities on gold ensures a solid evaluation of the number of molecules contributing to enhanced signals, facilitating comparability across substrates. The research discusses the importance of employing molecular surface density standards for advancing the field of surface-enhanced spectroscopies, encouraging collaborative efforts in protocol development and benchmarking in surface science.
Hybrid plasmonic nanodiamonds for thermometry and local photothermal therapy of melanoma: a comparative study
Authors: Gerasimova Elena N. , Fatkhutdinova Landysh I. , Vazhenin Ivan I. , Uvarov Egor I. , Vysotina Elizaveta , Mikhailova Lidia , Lazareva Polina A. , Kostyushev Dmitry , Abakumov Maxim , Parodi Alessandro , Yaroshenko Vitaly V. , Zuev Dmitry A. , Zyuzin Mikhail V. 
Published: August 2024

Abstract
Hyperthermia plays a significant role in cancer treatment by inducing cell damage through temperature elevation, often used alongside other treatment modalities. During hyperthermia therapy, temperature control is crucial. Here, we report on a simple synthesis route of hybrid plasmonic nanodiamonds either completely wrapped with an Au shell (NV@Au) or densely covered with Au NPs (NV@SiO

2

@Au). Such integration of nanodiamonds with Au NPs is advantageous both for heating and precise thermometry at nanoscale. After structural and optical investigations, heating abilities of the obtained plasmonic nanodiamonds were thoroughly inspected on glass, in association with living cells, and in tissue slices ex vivo, revealing their effective heat generation under excitation with light using a single excitation source. The developed hybrid plasmonic nanodiamonds were finally applied for local photothermal therapy of melanoma in vivo, demonstrating their efficacy in eradicating cancer cells and monitoring temperature during the process.
Extraction, purification, characterization and antidiabetic mechanisms of plant polysaccharides: a critical review
Authors: Li Meng , Law Douglas , Zhu Song , Najm Ahmed Abdul kareem , Fazry Shazrul , Othman Babul Airianah 
Published: August 2024

Abstract
Diabetes mellitus (DM) represents a heterogeneous and multifactorial metabolic disorder, leading to diverse economic challenges and health complications, significantly affecting individuals’ lives. Type 2 diabetes (T2DM) stands as the predominant form of diabetes, with its onset influenced by a range of genetic and environmental factors. Currently, conventional diabetic medications are employed in clinical practice, but they may entail certain side effects. Fortunately, diverse natural polysaccharides extracted from plants exhibit antidiabetic properties, which have been demonstrated to effectively mitigate hyperglycemia, reverse insulin resistance, and forestall complications associated with diabetes. Consequently, exploring the utilization of these polysaccharides as adjuncts to conventional therapies has emerged as a novel research direction in recent years. Thus, this review centers on the extraction, purification, and characterization of plant polysaccharides, providing an overview of the advancements in the antidiabetic effects and mechanisms of natural polysaccharides. This perspective offers fresh insights to explore potential research domains and enhances understanding for the development of diabetic drugs derived from polysaccharides.
Prinsip Manajemen Pendidikan Islam
Authors: Sahudi  
Published: August 2024

Penelitian ini bertujuan mendeskripsikan dan menganalisis 1) prinsip Manajemen Pendidikan Islam, sepuluh ciri/indikator iman dan akhlak, 2) prinsip Manajemen Pendidikan Islam (studi hadits sepuluh indikator iman dan akhlak), 3) penerapan sepuluh ciri/ indikator iman dan akhlak dalam Manajemen Pendidikan Islam.
Metode penelitian berbasis kepustakaan, dengan tahapan penelitian 1) mengumpulkan bahan penelitian, 2) membaca bahan kepustakaan, 3) membuat catatan penelitian, 4) mengolah catatan penelitian, dan 5) membuat kesimpulan. Studi hadits yang diterapkan dalam penelitian ini adalah menampilkan 1) sepuluh teks hadits dan sanad hadits yang berhubungan dengan sepuluh indikator iman dan akhlak, 2) terjemah hadits, 3) biografi singkat sanad/ perawi hadits, 4) analisa hadits, dan 5) implementasi hadits dalam Manajemen Pendidikan Islam.
Adapun subyek penelitian dalam artikel ini adalah studi hadits sepuluh indikator iman dan akhlak sebagai salah satu prinsip Manajemen Pendidikan Islam.
Hasil utama penelitian adalah 1) sepuluh indikator iman dan akhlak merupakan prinsip dasar dan utama dalam menjalankan Manajemen Pendidikan Islam 2) dalam kajian hadits, sepuluh indikator iman dan akhlak telah dipesankan oleh Rasulullah SAW kepada para sahabat dan umatnya. Semua menjadi dasar untuk mewujudkan kehidupan yang harmoni, terkhusus dalam menjalankan Manajemen Pendidikan Islam, 3) dalam Manajemen Pendidikan Islam, sepuluh indikator iman dan akhlak merupakan konsep-konsep yang memegang peran penting dalam membentuk sikap dan perilaku siswa yang positif. Oleh karena itu, penerapannya harus dilakukan secara bersama-sama oleh stake holder.
Ecosystem Model on Adaptive MOOC in Higher Education
Authors: Alwi Ahmad Chafid , Priyanto Priyanto , Dwiningrum Siti Irene Astuti , Nurlaily Akhsin , Raharjo Amrih Setyo 
Published: August 2024

This research aims to develop an adaptive MOOC ecosystem in universities. This study involved development research using the 4-D model, which consists of defining, designing, developing, and disseminating. The results indicate that in developing a MOOC ecosystem, it is necessary to conduct an in-depth analysis of users to find out what structures are needed. The context of MOOCs by companies is undoubtedly different from that of universities. As an educational institution, its stakeholders involve university leaders and researchers from lecturers. In the initial design, it is necessary to test user characteristics so that the MOOC system can make decisions on learning recommendations. We involved metacognitive testing and categorize so that users can learn to the fullest. In its application, validity tests were performed on experts to assess the product from development and on users. The test results showed excellent results. This ecosystem has also been disseminated to users and received a very good response. Moreover, several universities in Indonesia have the status of PTN-BH, which demands financial independence, so MOOC can be one of the breakthroughs to acquire income generation. Keywords: adaptive MOOC, MOOC ecosystem, higher education
Implementasi kurva kaplan-meier dan regresi lognormal terhadap lama pengobatan pasien diabetes mellitus dan faktor-faktor yang mempengaruhinya ( Studi Kasus di RSI Malang Unisma )
Authors: Rohmawati Ruly , Permadi Hendro 
Published: August 2024

Penelitian ini bertujuan menganalisa hasil kurva Kaplan-Meier untuk faktor dugaan yang mempengaruhi lama pengobatan pasien diabetes mellitus, serta memperoleh model regresi Lognormal dan mengetahui faktor yang paling berpengaruh terhadap lama pengobatan pasien diabetes mellitus di RSI Malang Unisma. Hasil kurva Kaplan-Meier menunjukkan bahwa pada kurva survival, cum survival semakin rendah seiring dengan semakin lamanya pengobatan pasien yang berarti bahwa semakin lama pengobatan pasien, maka peluang kondisi pasien membaik semakin kecil. Sedangkan dari kurva hazard dapat dilihat bahwa cum hazard semakin tinggi seiring dengan semakin lamanya pengobatan pasien yang berarti bahwa semakin lama pengobatan pasien, maka peluang pasien menjalani pengobatan semakin besar. Sedangkan dari metode regresi Lognormal diperoleh model regresi dengan faktor yang mempengaruhi lama pengobatan pasien diabetes mellitus adalah , yaitu kadar glukosa pasien diabetes mellitus.
Observatory of Town and Biomimetics For Urban Modeling and Architectural Design of Scientific Space in Landscaped Site.
Authors: Abderrahmane* MAACHOU 
Published: August 2024

Some modern architectural designs face difficulties in completion ,andthe dificult and complexe shapes lead to an increase in the cost of the project. The irregular urban planning of town creates an imbalance in the urban fabric and causes the functional problems. In this searches using biomimetics , we practice the urban planning of scientific space through projects of scientific use in several branches in a pivotal urban area whose scientific space extends to the eastern suburb of Ouzera Town.
After a brief presentation of an urban observatory from Ouzera Town that enhances the scientifc project, the scientific spaces are disgnated for the rapid exucution in scientific space. The architectural design derived from the plants and biological structures facilitates the urban realization insuring easy practices and achieving and urban form through landscape architecture that is consistent in ecologicaland landscaped area of Ouzera Terriory.
Association between sleep and gallstone disease in US adult: A population- based study
Authors: Xu Cheng , Song Zhen , Bian Xin-hai , Li Chong-chao 
Published: August 2024

Abstract

Objective
This study aimed to investigate the association between sleep factors (sleep duration and trouble sleeping) and the risk of gallstone disease.
Methods
Using data from the National Health and Nutrition Examination Survey (NHANES) database spanning from 2017 to 2020, we assessed the relationship between sleep factors (sleep duration and trouble sleeping) and the risk of gallstone disease through logistic regression analysis and subgroup analysis. We addressed the nonlinear relationship between sleep duration and the risk of gallstone disease using generalized additive models and smooth curve fittings.
Results
A total of 9,126 participants were included in the study, among whom 978 self-reported a history of gallstone disease. In the fully adjusted model, individuals with long sleep duration (> 9 hours) exhibited a lower likelihood of gallstone disease compared to those with short sleep duration (< 9 hours) (OR = 0.714, 95% CI: 0.527, 0.967). The generalized additive model and smoothed curve fitting further confirmed the negative association between sleep duration and gallstone disease risk. Trouble sleeping was positively correlated with gallstone disease (OR: 1.513, 95% CI: 1.270, 1.802). However, subgroup analysis indicated that the association between sleep factors and gallstone disease varied according to BMI grouping.
Conclusion
This nationally representative survey revealed a negative correlation between sleep duration and the risk of gallstone disease, while trouble sleeping showed a positive correlation with gallstone disease risk.
Catalyzing Green Lubricants into Graphitic Carbon Layers by Iron Single Atoms to Reduce Friction and Wear
Authors: Li Jinjin , Song Wei , Zeng Chongyang , Wong Janet S. S. , Ouyang Chuke , Erdemir Ali , Sun Shouyi , Lee Seungjoo , Zhang Weiwei , Luo Jianbin , Chen Xing 
Published: August 2024

Abstract

Reducing friction and wear in moving mechanical systems is essential for their intended functionality. This is currently accomplished using a large variety of anti-friction and anti-wear additives, that usually contain sulfur and phosphorous both of which cause harmful emission. Here, we introduce a series of diesters, typically dioctyl malate (DOM), as green and effective anti-friction and anti-wear additives which reduce wear by factors of 5–7 and friction by over 50% compared to conventional additives when tested under extreme pressures (up to 2.78 GPa). Surface studies show that these impressive properties are primarily due to the formation of a 30 nm graphitic tribofilm that protects rubbing surfaces against wear and hence provides low shear stress at nanoscale. This graphitic tribofilm is prone to form from diesters dereived from short-chain carboxylic acid due to their lone pair effect, which stabilizes the carbon free radicals. Furthermore, the formation of this tribofilm was catalyzed by nascent iron single atoms, which were in-situ generated due to the mechanochemical effects during sliding contact. Computational simulations provided additional insights into the steps involved in the catalytic decomposition of DOM by iron and the formation of a graphitic carbon tribofilm. Due to its superior anti-friction and wear properties, DOM holds promise to replace conventional additives, and thus provide a green and more effective alternative for next-generation lubricant formulations.
A Pilot Study: Interrupted Time-Series Analysis of the Impact of the COVID-19 Pandemic on Antimicrobial Stewardship in a Secondary Care Setting in the United Kingdom
Authors: Elshenawy Rasha Abdelsalam , Umaru Nkiruka , Aslanpour Zoe 
Published: August 2024

Abstract

This pilot study examines the impact of the COVID-19 pandemic on antimicrobial stewardship (AMS) practices in a UK secondary care setting. An interrupted time-series analysis compared antibiotic prescribing patterns for respiratory tract infections (RTIs) before (2019) and during (2020) the pandemic. The study, involving 80 admissions, highlights shifts in AMS practices. Community Acquired Pneumonia (CAP) was the most frequent diagnosis. Compliance with AMS practices, based on the PHE SMTF toolkit, showed 100% for clinical indication and drug allergy documentation. However, CURB-65 Score compliance remained at 60%, and other AMS interventions varied, with decreased compliance during the pandemic. RTI admissions peaked at 15 in December 2019, declined to 9 in June and September 2020. The study emphasizes the need for adaptable AMS strategies during health crises to mitigate antimicrobial resistance and maintain effective patient care. Future research should focus on developing resilient AMS frameworks for global health emergencies.
Investigation on the Use of Microorganisms in the Microbiological Breakdown of Synthetic Polymers
Authors: Diddigi Geeta , B Ramalingappa 
Published: August 2024

Abstract

Although a wide spectrum of consumers demand the exceptional performance qualities that polymers offer to modern society, managing the fate of polymers in the environment has grown to be a major management challenge. For product engineers looking for features with a long lifetime, polymer applications provide appealing molecular architectures. These qualities play a significant role in how long plastics or polymers can last in the environment. Recent reports of microbial breakdown of polymeric materials give new emerging technological alternatives to change the significant pollution issue incurred via use of polymers/plastics. There is a substantial body of literature from which prospective biological technology future development paths might be inferred. To supply the database from which a new technique was built, each report of microbial driven polymer degradation must be characterized in great detail. The kinetics of the degradation process must be addressed as part of the development, and novel methods to accelerate the rate of deterioration must be discovered. The quest to design new technologies involves an implicit awareness of how biotic and abiotic deterioration interact.