bluuebunny/crossref_metadata_2025_split huggingface dataset:
Refugee Entrepreneurship: Resolving Multi-contextuality and Differential Exclusion
Authors: Yetkin Ugur , Tunçalp Deniz 
Published: August 2024

AbstractThis study examines the multi-contextual dynamics of refugee entrepreneurship through the lens of embeddedness. It attempts to explain the interplay of inclusion and exclusion within a host society. For this purpose, the study qualitatively analyses the narratives of 39 Syrian refugee entrepreneurs and four critical informants in Türkiye. Our findings reveal a diverse set of refugee entrepreneurs, categorized into survival, ethnic-targeting, and integrating entrepreneurs, based on their motivations and level of embeddedness. Interestingly, as refugee entrepreneurs become more embedded in the host country, they experience increased exclusion due to various societal factors. To navigate these challenges, entrepreneurs continually negotiate their societal position using innovative strategies to combat exclusion. Our study incorporates social, political, institutional, and spatial contexts across host, home, and third countries. Thus, it extends the embeddedness literature by highlighting refugee entrepreneurs' multi-layered and multi-locational embeddedness. Our findings also emphasise the significant role of political embeddedness, which Research often overlooks. Differentially excluding refugee entrepreneurs from society and their counter-strategies are closely tied to their limited political embeddedness. Finally, we discuss the ethical and policy implications of promoting the inclusion of refugee entrepreneurs and contributing to the United Nations' Sustainable Development Goals. We argue that clear integration policies, removal of institutional barriers, and international cooperation are necessary.
ArcMatch: high-performance subgraph matching for labeled graphs by exploiting edge domains
Authors: Bonnici Vincenzo , Grasso Roberto , Micale Giovanni , Maria Antonio di , Shasha Dennis , Pulvirenti Alfredo , Giugno Rosalba 
Published: August 2024

AbstractConsider a large labeled graph (network), denoted the target. Subgraph matching is the problem of finding all instances of a small subgraph, denoted the query, in the target graph. Unlike the majority of existing methods that are restricted to graphs with labels solely on vertices, our proposed approach, named can effectively handle graphs with labels on both vertices and edges. ntroduces an efficient new vertex/edge domain data structure filtering procedure to speed up subgraph queries. The procedure, called path-based reduction, filters initial domains by scanning them for paths up to a specified length that appear in the query graph. Additionally, ncorporates existing techniques like variable ordering and parent selection, as well as adapting the core search process, to take advantage of the information within edge domains. Experiments in real scenarios such as protein–protein interaction graphs, co-authorship networks, and email networks, show that s faster than state-of-the-art systems varying the number of distinct vertex labels over the whole target graph and query sizes.
The impact of corporate social responsibility on green innovation: do industry, data type and region matter? a meta-analysis research
Authors: Gurler Hasan Emin 
Published: August 2024

AbstractThis study aims to explore the relationship between corporate social responsibility (CSR) and green innovation due to the fragmented and inconsistent findings in previous research. To achieve this, a meta-analysis is conducted on 29 peer-reviewed articles. The aim is to unravel the overall relationship between CSR and green innovation and identify potential factors that may influence this relationship, such as industry, data type, and region. The author’s results concluded that the robust relationship between CSR and green innovation remains consistent and strong, whether in manufacturing or other industries. Moreover, the outcomes indicate that research based on primary data demonstrates a more robust relationship between CSR and green innovation than secondary data studies. The findings also bring attention to regional differences in the relationship between CSR and green innovation, with studies conducted in North America displaying the most notable influence. This study represents the first-ever comprehensive meta-analytic investigation into the relationship between CSR and green innovation.
Randomized single-blinded study comparing sedation effectiveness and hemodynamic stability of remifentanil vs dexmedetomidine infusion for electrophysiology procedures in patients of National Heart Institute cathlab
Authors: Hassan Rozaini , Mutalib Azlee Abdul , Shang Chen Yi , Sachdev Nirpal Singh , Rahman Farkad Abdul , Ling Esther Siew Lee 
Published: August 2024

Abstract
Background
While studies comparing the effectiveness of remifentanil and dexmedetomidine are prevalent in other nations, using remifentanil alone is uncommon in Malaysia. This research aims to evaluate the effectiveness of sedation with remifentanil or dexmedetomidine infusion in monitored anesthesia care for electrophysiology procedures.

Methods
This study is a single-center, single-blinded, prospective randomized clinical study. One hundred twenty patients were randomized into two groups (remifentanil vs dexmedetomidine). Demographic characteristics and clinical outcomes, including level of sedation, vital signs, and patient satisfaction were monitored and recorded.

Results
Group R showed a higher mean observer’s assessment of alertness/sedation score (3.9 ± 0.7 vs 3.6 ± 0.8; p = 0.008), mean arterial pressure (92.0 ± 12.0 vs 83.0 ± 13.0 mmHg; p < 0.001), heart rate (82.0 ± 20.0 vs 73.0 ± 18.0 beats/min; p = 0.006), systolic blood pressure (139.0 ± 16.0 vs 123.0 ± 17.0 mmHg; p < 0.001) and diastolic blood pressure (75.0 ± 13.0 vs 69.0 ± 14.0 mmHg; p = 0.009) than Group D. Oxygen saturation (99.0 ± 1.0%; p = 0.220) and respiration rate (16.0 ± 3.0 breaths/min; p = 0.361) for both groups were the same. Adverse events, including hypotension, bradycardia, and respiratory depression were observed in both groups. Both groups gave positive responses ranging from fair to good for patient satisfaction.

Conclusion
Dexmedetomidine is a better choice of anesthesia as it was associated with a higher level of sedation, more stable hemodynamics, lower incidence of adverse events, and better patient satisfaction.

Graphical Abstract
Epidermodysplasia Verruciformis and Vδ2 γδ T-cell Expansion in STK4 Deficiency
Authors: Ying Wenjing , Long Xin , Vandergriff Travis , Karnati Hemanth , Heberton Meghan , Chen Mingyi , Wang Xiaochuan , Wysocki Christian , Kong Xiao-Fei 
Published: August 2024

AbstractThe clinical penetrance of infectious diseases varies considerably among patients with inborn errors of immunity (IEI), even for identical genetic defects. This variability is influenced by pathogen exposure, healthcare access and host-environment interactions. We describe here a patient in his thirties who presented with epidermodysplasia verruciformis (EV) due to infection with a weakly virulent beta-papillomavirus (HPV38) and CD4+ T-cell lymphopenia. The patient was born to consanguineous parents living in the United States. Exome sequencing identified a previously unknown biallelic STK4 stop-gain mutation (p.Trp425X). The patient had no relevant history of infectious disease during childhood other than mild wart-like lesion on the skin, but he developed diffuse large B-cell lymphoma (DLBCL) and EBV viremia with a low viral load in his thirties. Despite his low CD4+ T-cell count, the patient had normal counts of CD3+ cells, predominantly double-negative T cells (67.4%), which turned out to be Vδ2+ γδ T cells. γδ T-cell expansion has frequently been observed in the 33 reported cases with STK4 deficiency. The Vδ2 γδ T cells of this STK4-deficient patient are mostly CD45RA-CD27+CCR7+ central memory γδT cells, and their ability to proliferate in response to T-cell activation was impaired, as was that of CD4+ T cells. In conclusion, γδ T-cell expansion may act as a compensatory mechanism to combat viral infection, providing immune protection in immunocompromised individuals.
Novel algorithms based on forward-backward splitting technique: effective methods for regression and classification
Authors: Atalan Yunus , Hacıoğlu Emirhan , Ertürk Müzeyyen , Gürsoy Faik , Milovanović Gradimir V. 
Published: August 2024

AbstractIn this paper, we introduce two novel forward-backward splitting algorithms (FBSAs) for nonsmooth convex minimization. We provide a thorough convergence analysis, emphasizing the new algorithms and contrasting them with existing ones. Our findings are validated through a numerical example. The practical utility of these algorithms in real-world applications, including machine learning for tasks such as classification, regression, and image deblurring reveal that these algorithms consistently approach optimal solutions with fewer iterations, highlighting their efficiency in real-world scenarios.
Is a Problem-Solving Intervention with Workplace Involvement for Employees on Sickness Absence Due to Common Mental Disorders More Effective, than Care as Usual, in Reducing Sickness Absence Days? Results of a Cluster-Randomised Controlled Trial in Primary Health Care
Authors: Karlsson Ida , Frantz Anna , Axén Iben , Bergström Gunnar , Bültmann Ute , Finnes Anna , Holmgren Kristina , Kwak Lydia , Björk Brämberg Elisabeth 
Published: August 2024

Abstract
Purpose
The aim was to evaluate the effectiveness of a problem-solving intervention with workplace involvement (PSI-WPI) added to care as usual (CAU) in reducing sickness absence days among employees with common mental disorders compared to CAU alone in Swedish primary health care on a monthly basis over 18-months follow-up.

Methods
We conducted a cluster-randomised controlled trial including 197 employees blinded to allocation (85 PSI-WPI and 112 CAU). As sickness absence data was skewed and over-dispersed, generalised estimating equations was used to enable a comparison between the intervention and control group for each month of the follow-up period.

Results
The median number of sickness absence days over the 18-month follow-up was 78 days, inter-quartile range (IQR) 18–196 for employees receiving PSI-WPI and 64 days, IQR 18–161 for employees receiving CAU. The time x group generalised estimating equations analysis showed no statistically significant difference in sickness absence days per month.

Conclusion
The addition of a PSI-WPI to CAU was not more effective in reducing sickness absence days. This may be explained by the primary health care context, lack of specialisation in occupational health and the Swedish social insurance system with specific time limits.
Trial registration.
The trial was registered at ClinicalTrials.gov, identifier: NCT03346395 on January 12th, 2018.
Physically adjusted ground motion prediction equations for induced seismicity at Preston New Road, UK
Authors: Suroyo Pungky Megasari , Sunny Jaleena , Edwards Benjamin 
Published: August 2024

AbstractPredicting ground motions due to induced seismicity is a challenging task owing to the scarcity of data and heterogeneity of the uppermost crust. Dealing with this requires a thorough understanding of the underlying physics and consideration of inter-site variability. The most common ground motion model used in practice is the parametric ground motion prediction equation (GMPE), of which hundreds exist in the literature. However, relatively few are developed with a focus on induced seismicity. Developing GMPEs that are specific to an appropriate magnitude-distance range ($$R < 30$$

R
<
30

km; $$2 \le M \le 6$$

2
≤
M
≤
6

) is important for induced seismicity applications. This paper proposes a framework for the development of physically-based GMPEs to provide more accurate and reliable estimates of the potential induced-seismicity ground motion hazard, allowing for better risk assessment and management strategies. To demonstrate this approach, a new set of GMPEs for the 2018-2019 induced seismicity sequence at the Preston New Road (PNR) shale gas site near Blackpool, United Kingdom, is presented. The physically-based GMPE was developed based on a pseudo-finite-fault stochastic ground motion simulation, calibrated with parameters derived from the spectral analysis of weak-motion records from induced seismic events. An optimization-based calibration technique using the area metric (AM) was subsequently performed to calibrate optimal parameters for simulating ground motion at the PNR site. Finally, using a suite of forward simulations for events with $$1 \le M \le 6$$

1
≤
M
≤
6

recorded at distances up to 30 km, combined with empirical data, a location-specific GMPE was derived through adjustment of an existing model.
Efficient adsorption of thorium and cerium from Rosetta monazite concentrate using a novel phosphorylated Schiff-base adsorbent
Authors: Gado Mohamed A. 
Published: August 2024

Abstract(Pyridine-2,5-diylbis(azaneylylidene)) bis-(methaneylylidene)) bis(benzene-5,1,3-triyl) tetrakis (hydrogen phosphonate) (PZMB) was successfully synthesized for Th(IV) and Ce(IV) adsorption, the adsorption parameters evaluated and found to be pH 3.5, time 60 min, dose 0.15 g. Adsorption kinetics, isotherm, and thermodynamics studies. Adsorption kinetics studies show that adsorbent follow pseudo-second-order model while isotherm studies conclude that adsorption processes fitted Langmuir and D-R isotherm model. The maximum adsorption capacity of BZMB of Th(IV) and Ce(IV) are 366.4 and 244.53 mg/g respectively, Thermodynamic studies indicate both adsorption processes exhibited by the PZMB were endothermic, spontaneous and sorption occurs in a random manner.
A variational model for finger-driven cell diffusion in the extracellular matrix
Authors: Favata Antonino , Rodella Andrea , Vidoli Stefano 
Published: August 2024

AbstractWe present a simple chemo-mechanical variational model for a fibrous material that describes (i) the emergence of the anisotropy due to microscopic buckling instabilities (ii) a diffusion in the substrate of the cell phase driven by the new created macroscopic bands characterized by intense compressive deformation. The model is applicable for simulating the spreading of cells within tissues and their interaction with tissue remodeling during mesenchymal migration.
Quality and Safety Considerations for Therapeutic Products Based on Extracellular Vesicles
Authors: Takakura Yoshinobu , Hanayama Rikinari , Akiyoshi Kazunari , Futaki Shiroh , Hida Kyoko , Ichiki Takanori , Ishii-Watabe Akiko , Kuroda Masahiko , Maki Kazushige , Miura Yasuo , Okada Yoshiaki , Seo Naohiro , Takeuchi Toshihide , Yamaguchi Teruhide , Yoshioka Yusuke 
Published: August 2024

AbstractExtracellular vesicles (EVs) serve as an intrinsic system for delivering functional molecules within our body, playing significant roles in diverse physiological phenomena and diseases. Both native and engineered EVs are currently the subject of extensive research as promising therapeutics and drug delivery systems, primarily due to their remarkable attributes, such as targeting capabilities, biocompatibility, and low immunogenicity and mutagenicity. Nevertheless, their clinical application is still a long way off owing to multiple limitations. In this context, the Science Board of the Pharmaceuticals and Medical Devices Agency (PMDA) of Japan has conducted a comprehensive assessment to identify the current issues related to the quality and safety of EV-based therapeutic products. Furthermore, we have presented several examples of the state-of-the-art methodologies employed in EV manufacturing, along with guidelines for critical processes, such as production, purification, characterization, quality evaluation and control, safety assessment, and clinical development and evaluation of EV-based therapeutics. These endeavors aim to facilitate the clinical application of EVs and pave the way for their transformative impact in healthcare.
Sosa on scepticism and the background
Authors: Pritchard Duncan 
Published: August 2024

AbstractSosa’s influential work on virtue epistemology includes an intriguing proposal about background commitments, which he in turn relates to the Wittgensteinian notion of a hinge commitment. A critique is offered of Sosa’s proposal, particularly with regard to how he aims to apply it to the problem of radical scepticism. In light of this critique, an alternative conception of hinge commitments is offered that enables them to play a very different role in our treatment of radical scepticism.
Health-related quality of life in psychiatric outpatients: a cross-sectional study of associations with symptoms, diagnoses, and employment status
Authors: Havnen Audun , Lindberg Martin Schevik , Lundqvist Jakob , Brattmyr Martin , Hjemdal Odin , Solem Stian 
Published: August 2024

Abstract
Background
This cross-sectional study aimed to explore health-related quality of life (HRQoL) in a large heterogeneous patient sample seeking outpatient treatment at a specialist mental health clinic.

Method
A sample of 1947 patients with common mental disorders, including depressive-, anxiety-, personality-, hyperkinetic- and trauma-related disorders, completed the EuroQoL 5-Dimension 5-Level (EQ-5D-5L) to assess HRQoL. We investigated clinical and sociodemographic factors associated with the EQ-5D index and the EQ Visual Analogue Scale (VAS) using regression analyses.

Results
The sample reported lower HRQoL compared with the general population and primary mental health care patients. Sick leave, disability pension, work assessment allowance, and more symptoms of anxiety and depression were associated with lower EQ-5D index and EQ VAS scores. Furthermore, being male, use of pain medication and having disorders related to trauma were associated with reduced EQ-5D index scores, while hyperkinetic disorders were associated with higher EQ-5D index scores.

Conclusion
HRQoL of psychiatric outpatients is clearly impaired. This study indicated a significant association between employment status, symptom severity, and HRQoL in treatment-seeking outpatients. The findings highlight the importance of assessing HRQoL as part of routine clinical assessment.
The Gendered Influence of Cross-Gender Friends on the Development of Adolescents’ Gender Role Attitudes
Authors: Kretschmer David 
Published: August 2024

AbstractGender role attitudes have important implications at the individual, family, and societal levels, underscoring the importance of understanding their development. Although parents predominate in the socialization of gender role attitudes in childhood, the influence of friends increases during adolescence. In particular, cross-gender friends can provide unique insights and perspectives on another gender group, making them likely to shape gender role attitudes. However, empirical explorations of the link between gender role attitudes and cross-gender friendships have been rare. Furthermore, the few studies conducted have yielded ambiguous results and have struggled to separate the influence of cross-gender friends from a selection of such friendships based on gender role attitudes. This study addresses these limitations by using longitudinal social network models to assess the co-evolution of friendship networks and gender role attitudes among 3,194 youth (Mage = 15.2, SD = 0.67, 51% female) in German schools. The findings reveal that, after accounting for selection processes, boys with cross-gender friends develop more egalitarian gender role attitudes, while girls’ attitudes are unaffected by cross-gender friendships. These findings suggest that promoting cross-gender friendships among adolescent boys holds the potential to foster egalitarian gender role attitudes.
Deep disagreement across moral revolutions
Authors: Lane Benedict 
Published: August 2024

AbstractMoral revolutions are rightly coming to be recognised as a philosophically interesting and historically important mode of moral change. What is less often acknowledged is that the very characteristics that make a moral change revolutionary pose a fundamental challenge to the possibility of moral progress. This is because moral revolutions are characterised by a diachronic form of deep moral disagreement: moral agents on either side of a moral revolution adopt different standards for assessing the merits of a moral argument, and according to the standards they adopt, agents on neither side of the revolution ought to accept the arguments being put forward by those on the other. This threatens to undermine the progressive status of many of our most celebrated historical examples of moral revolutions: if a moral revolution only looks progressive in light of a change in evaluative standards it itself brought about, then moral progress seems relative to a particular historical perspective; if prior to a moral revolution taking place the moral arguments in its favour fall short of the relevant standards, moral revolutions can never be the outcome of rational argumentation. This apparent relativism and irrationality sits uncomfortably alongside our common-sense intuition that the moral revolutions upon which our contemporary moral worldview rests count as genuine moral progress. In this paper, I deepen currently popular Kuhnian-inspired accounts of moral revolution by incorporating Wittgensteinian ideas from Philosophical Investigations and On Certainty. The result is an original way of thinking about deep moral disagreements, moral revolutions, and moral progress.
Repeated injections of vitamin E and Se improves testicular morphology, testosterone and in vitro and in vivo sperm fertility in subfertile rabbits
Authors: Fadl Aya M. , Samir Haney , Shahat Abdallah M. 
Published: August 2024

AbstractSubfertility is a multifactorial disorder that affects the rabbit production industry. However, subfertility may be treated by using a simple intervention such as vitamin supplementation. Vitamin E and selenium (Se) are potent antioxidants that protect the male reproductive system. The aim of this study is to determine the effects of vitamin E and Se on testicular size, semen quality and freezability, antioxidant activity, testosterone levels, and fertility in subfertile rabbits. Twenty-one New Zealand rabbits were classified as subfertile rabbits based on their semen characteristics and fertility records. The rabbits were randomly allocated into 3 equal groups (G1: control; G2: injected with Vit E 100 IU/head + Se 0.1 mg/kg b.w.; G3: injected with Vit E 200 IU/head + Se 0.2 mg/kg b.w. once weekly for 8 weeks).Once weekly for 8 W, blood samples were collected to measure serum testosterone level and total antioxidant capacity (TAC), and semen samples were collected by artificial vagina to assess the quality of fresh and frozen semen. At the 8th week of the study, 150 multiparous does were artificially inseminated with fresh semen to assess the fertility of rabbits after treatment; 50 does for each group. At the end of the study, rabbits were slaughtered to assess testicular morphometry. Fresh and post-thaw semen quality parameters were significantly (p < 0.05) higher in G3in comparison with G2and G1, respectively. Also, testosterone level was significantly (p < 0.05) increased at the 2nd week in G3in comparison with other groups. Conception and kindling rates were significantly (p < 0.05) higher in does which were inseminated with semen fromG3. In conclusion, injection of vitamin E and selenium at a higher dose (G3) improved the testicular morphology, quality of fresh and post-thaw semen, and most importantly, the fertility of subfertile rabbits.