bluuebunny/crossref_metadata_2025_split huggingface dataset:
SUÁREZ BRIONES, Beatriz (ed.): Las lesbianas (no) somos mujeres. En torno a Monique Wittig. Icaria Editorial, Barcelona 2013; IDEM (ed.): Feminismos lesbianos y queer. Representación, visibilidad y políticas. Plaza y Valdés, Madrid 2014.
Authors: Romero Morales Yasmina 
Published: April 2015

Reseña de SUÁREZ BRIONES, Beatriz (ed.): Las lesbianas (no) somos mujeres. En torno a Monique Wittig. Icaria Editorial, Barcelona 2013; IDEM (ed.): Feminismos lesbianos y queer. Representación, visibilidad y políticas. Plaza y Valdés, Madrid 2014.
Tieftemperatur‐Isolierung des bicyclischen Phosphinophosphoniumsalzes [Mes*2P4Cl][GaCl4]
Authors: Bresien Jonas , Faust Kirill , Schulz Axel , Villinger Alexander 
Published: April 2015

AbstractDie Reaktion von [ClP(μ‐PMes*)]2 (1) mit der Lewis‐Säure GaCl3 ergab ein bisher unbekanntes Tetraphosphabicyclo[1.1.0]butan‐2‐iumsalz, [Mes*P4(Cl)Mes*][GaCl4] (3[GaCl4]), dessen bicyclisches P4‐Rückgrat ein positiv geladenes Phosphoniumzentrum enthält. Die Bildung der Titelverbindung wurde durch Tieftemperatur‐NMR‐Experimente untersucht. Hierdurch konnte ein intermediäres cyclisches Tetraphospheniumkation identifiziert werden, das durch Dimethylbutadien (dmb) abgefangen wurde. Alle Verbindungen wurden vollständig durch experimentelle und rechnerische Methoden charakterisiert.
High‐Yield Electrosynthesis of Hydrogen Peroxide from Oxygen Reduction by Hierarchically Porous Carbon
Authors: Liu Yanming , Quan Xie , Fan Xinfei , Wang Hua , Chen Shuo 
Published: April 2015

AbstractH2O2 production by electroreduction of O2 is an attractive alternative to the current anthraquinone process, which is highly desirable for chemical industries and environmental remediation. However, it remains a great challenge to develop cost‐effective electrocatalysts for H2O2 synthesis. Here, hierarchically porous carbon (HPC) was proposed for the electrosynthesis of H2O2 from O2 reduction. It exhibited high activity for O2 reduction and good H2O2 selectivity (95.0–70.2 %, most of them >90.0 % at pH 1–4 and >80.0 % at pH 7). High‐yield H2O2 generation has been achieved on HPC with H2O2 concentrations of 222.6–62.0 mmol L−1 (2.5 h) and corresponding H2O2 production rates of 395.7–110.2 mmol h−1 g−1 at pH 1–7 and −0.5 V. Moreover, HPC was energy‐efficient for H2O2 production with current efficiency of 81.8–70.8 %. The exceptional performance of HPC for electrosynthesis of H2O2 could be attributed to its high content of sp3‐C and defects, large surface area and fast mass transfer.
Electrodeposited Cobalt‐Phosphorous‐Derived Films as Competent Bifunctional Catalysts for Overall Water Splitting
Authors: Jiang Nan , You Bo , Sheng Meili , Sun Yujie 
Published: April 2015

AbstractOne of the challenges to realize large‐scale water splitting is the lack of active and low‐cost electrocatalysts for its two half reactions: H2 and O2 evolution reactions (HER and OER). Herein, we report that cobalt‐phosphorous‐derived films (Co‐P) can act as bifunctional catalysts for overall water splitting. The as‐prepared Co‐P films exhibited remarkable catalytic performance for both HER and OER in alkaline media, with a current density of 10 mA cm−2 at overpotentials of −94 mV for HER and 345 mV for OER and Tafel slopes of 42 and 47 mV/dec, respectively. They can be employed as catalysts on both anode and cathode for overall water splitting with 100 % Faradaic efficiency, rivalling the integrated performance of Pt and IrO2. The major composition of the as‐prepared and post‐HER films are metallic cobalt and cobalt phosphide, which partially evolved to cobalt oxide during OER.
Magnetic field measurements of ϵ Eridani from Zeeman broadening
Authors: Lehmann L. T. , Künstler A. , Carroll T. A. , Strassmeier K. G. 
Published: April 2015

AbstractWe present new magnetic field measurements of the K2 main‐sequence star ϵ Eri based on principal components analysis (PCA) line‐profile reconstructions. The aim of this paper is to quantify the surface‐averaged magnetic field and search for possible variations. A total of 338 optical échelle spectra from our robotic telescope facility STELLA with a spectral resolution of 55 000 were available for analysis. This time‐series was used to search for the small line‐profile variations due to a surface magnetic field with the help of a PCA. Evidence for a spatial and temporal inhomogeneous magnetic field distribution is presented. The mean, surface averaged, magnetic field strength was found tobe 〈B〉 = 186 ± 47 G in good agreement with previous Zeeman‐broadening measurements. Clear short‐term variations of the surface averaged magnetic field of up to few tens Gauss were detected together with evidence for a three‐year cycle in the surface‐averaged magnetic field of ϵ Eri. (© 2015 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Ionic liquid activated Bacillus subtilis lipase A variants through cooperative surface substitutions
Authors: Zhao Jing , Jia Ning , Jaeger Karl‐Erich , Bocola Marco , Schwaneberg Ulrich 
Published: April 2015

ABSTRACTThe interest in performing enzyme‐catalyzed reactions in amphiphilic systems, e.g., imidazolium‐based ionic liquids (ILs) or surfactants, has been increased over the past decades. Directed protein evolution has been successful in tailoring enzymes for desired properties. Herein, nine IL‐resistant Bacillus subtilis lipase A variants, particularly an IL‐activated variant M1 (M134N/N138S/L140S), were identified by directed evolution. For instance, variant M2 (M134R/L140S) showed almost doubled specific activity (16.9 vs. 9.4 U/mg) and resistance (233% vs. 111%) at 9 vol% 1‐butyl‐3‐methylimidazolium trifluoromethanesulfonate ([C4mim][TfO]) compared with wild–type. The specific activities and resistance of purified individual single and double variants have been studied in five different IL‐aqueous mixtures. The re‐activation of lipase variant M1 (not wild–type) at high IL concentration was attributed to the cooperative effect of three surface substitutions (M134N, N138S, L140S) near the substrate‐binding cleft. The presence of IL/substrate clusters under assay conditions was likely related to the re‐activation effect. This study provides first example of IL‐activated lipase variant generated by protein engineering, and helps to better understand the protein‐IL interaction. Biotechnol. Bioeng. 2015;112: 1997–2004. © 2015 Wiley Periodicals, Inc.
Evaluating algal growth performance and water use efficiency of pilot‐scale revolving algal biofilm (RAB) culture systems
Authors: Gross Martin , Mascarenhas Vernon , Wen Zhiyou 
Published: April 2015

ABSTRACTA Revolving Algal Biofilm (RAB) growth system in which algal cells are attached to a flexible material rotating between liquid and gas phases has been developed. In this work, different configurations of RAB systems were developed at pilot‐scale by retrofitting the attachment materials to a raceway pond (2000‐L with 8.5 m2 footprint area) and a trough reservoir (150 L with 3.5 m2 footprint area). The algal growth performance and chemical composition, as well as the water evaporative loss and specific water consumption were evaluated over a period of nine months in a greenhouse environment near Boone, Iowa USA. Additionally a raceway pond was run in parallel, which served as a control. On average the raceway‐based RAB and the trough‐based RAB outperformed the control pond by 309% and 697%, respectively. A maximum productivity of 46.8 g m−2 day−1 was achieved on the trough‐based RAB system. The evaporative water loss of the RAB system was modeled based on an energy balance analysis and was experimentally validated. While the RAB system, particularly the trough‐based RAB, had higher water evaporative loss, the specific water consumption per unit of biomass produced was only 26% (raceway‐based RAB) and 7% (trough‐based RAB) of that of the control pond. Collectively, this research shows that the RAB system is an efficient algal culture system and has great potential to commercially produce microalgae with high productivity and efficient water use. Biotechnol. Bioeng. 2015;112: 2040–2050. © 2015 Wiley Periodicals, Inc.
Challenges and opportunities for microalgae‐mediated CO2 capture and biorefinery
Authors: Seth Jyoti R. , Wangikar Pramod P. 
Published: April 2015

ABSTRACTAquacultures of microalgae are frontrunners for photosynthetic capture of CO2 from flue gases. Expedient implementation mandates coupling of microalgal CO2 capture with synthesis of fuels and organic products, so as to derive value from biomass. An integrated biorefinery complex houses a biomass growth and harvesting area and a refining zone for conversion to product(s) and separation to desired purity levels. As growth and downstream options require energy and incur loss of carbon, put together, the loop must be energy positive, carbon negative, or add substantial value. Feasibility studies can, thus, aid the choice from among the rapidly evolving technological options, many of which are still in the early phases of development. We summarize basic engineering calculations for the key steps of a biorefining loop where flue gases from a thermal power station are captured using microalgal biomass along with subsequent options for conversion to fuel or value added products. An assimilation of findings from recent laboratory and pilot‐scale experiments and life cycle analysis (LCA) studies is presented as carbon and energy yields for growth and harvesting of microalgal biomass and downstream options. Of the biorefining options, conversion to the widely studied biofuel, ethanol, and manufacture of the platform chemical, succinic acid are presented. Both processes yield specific products and do not demand high‐energy input but entail 60–70% carbon loss through fermentative respiration. Thermochemical conversions, on the other hand, have smaller carbon and energy losses but yield a mixture of products. Biotechnol. Bioeng. 2015;112: 1281–1296. © 2015 Wiley Periodicals, Inc.
Promotional Effect of Ag on the Catalytic Activity of Au for Glycerol Electrooxidation in Alkaline Medium
Authors: Garcia Amanda C. , Caliman Julia , Ferreira Eduardo B. , Tremiliosi‐Filho Germano , Linares José J. 
Published: April 2015

AbstractThe potential of silver as an auxiliary metal for gold in the electrochemical oxidation of glycerol in alkaline medium is studied. Three bimetallic materials (Au3Ag/C, AuAg/C, and AuAg3/C) and the corresponding monometallic reference materials (Au/C and Ag/C) are prepared by chemical reduction of their precursors with glycerol. Half‐cell measurements evidence the beneficial effect of Ag on the electrocatalytic activity of Au for glycerol oxidation owing to decreased onset potential and higher current density in chronoamperometry, with an optimum formulation of AuAg/C. These results are confirmed by the single‐cell performance of AuAg/C, which, despite having half the Au loading, has a higher open‐circuit voltage than Au/C and a similar maximum power density. The results are correlated with the structural and electronic features of these materials, which are widely discussed in other works.
Generation of Photocurrent by Visible‐Light Irradiation of Conjugated Dawson Polyoxophosphovanadotungstate–Porphyrin Copolymers
Authors: Azcarate Iban , Huo Zhaohui , Farha Rana , Goldmann Michel , Xu Hualong , Hasenknopf Bernold , Lacôte Emmanuel , Ruhlmann Laurent 
Published: April 2015

AbstractFour hybrid polyoxometalate–porphyrin copolymer films were obtained by the electrooxidation of zinc octaethylporphyrin in the presence of four different Dawson‐type polyoxometalates bearing two pyridyl groups (POM(py)2) with various spacers. The POM monomers were designed around 1,3,5‐trisubstituted benzene rings. Two of the substituents of the benzene ring are linked to the pyridyl groups, and the third is connected to the POM subunit. The four monomers vary in the relative positions of the nitrogen atoms of the pyridine rings or in the distance from the carbonyl group. The monomers were fully characterized by 1H, 31P, and 13C NMR spectroscopy, electrospray mass spectrometry, IR and UV/Vis spectroscopy, and electrochemistry. The copolymers were characterized by UV/Vis spectroscopy, X‐ray photoelectron spectroscopy, electrochemistry, and AFM. Their photovoltaic performance under visible light irradiation was investigated by photocurrent transient measurements under visible illumination.
Smart Soft‐Templating Synthesis of Hollow Mesoporous Bioactive Glass Spheres
Authors: Li Yunqi , Bastakoti Bishnu Prasad , Yamauchi Yusuke 
Published: April 2015

AbstractHollow bioactive glass spheres with mesoporous shells were prepared by using dual soft templates, a diblock co‐polymer poly(styrene‐b‐acrylic acid) (PS‐b‐PAA) and a cationic surfactant cetyltrimethylammonium bromide (CTAB). Hollow mesoporous bioactive glass (HMBG) spheres comprise the large hollow interior with vertical mesochannels in shell, which realize large uptake of drugs and their sustained release. The formation of hydroxyapatite layer on the surface of HMBG particles shows the clear evidence for promising application in bone regeneration.
Selective Targeting of the TPX2 Site of Importin‐α Using Fragment‐Based Ligand Design
Authors: Holvey Rhian S. , Valkov Eugene , Neal David , Stewart Murray , Abell Chris 
Published: April 2015

AbstractProtein–protein interactions are difficult therapeutic targets, and inhibiting pathologically relevant interactions without disrupting other essential ones presents an additional challenge. Herein we report how this might be achieved for the potential anticancer target, the TPX2–importin‐α interaction. Importin‐α is a nuclear transport protein that regulates the spindle assembly protein TPX2. It has two binding sites—major and minor—to which partners bind. Most nuclear transport cargoes use the major site, whereas TPX2 binds principally to the minor site. Fragment‐based approaches were used to identify small molecules that bind importin‐α, and crystallographic studies identified a lead series that was observed to bind specifically to the minor site, representing the first ligands specific for this site. Structure‐guided synthesis informed the elaboration of these fragments to explore the source of ligand selectivity between the minor and major sites. These ligands are starting points for the development of inhibitors of this protein–protein interaction.
Evaluation of the effect of food and age on the pharmacokinetics of oral netupitant and palonosetron in healthy subjects: A randomized, open‐label, crossover phase 1 study
Authors: Calcagnile Selma , Lanzarotti Corinna , Gutacker Michaela , Jakob‐Rodamer Verena , Peter Kammerer Klaus , Timmer Wolfgang 
Published: April 2015

AbstractAntiemetic treatment compliance is important to prevent chemotherapy‐induced nausea and vomiting, a feared chemotherapy side effect. NEPA, a new oral fixed combination of netupitant, a highly selective NK1 receptor antagonist (RA), and palonosetron, a second‐generation 5‐HT3 RA, targets dual antiemetic pathways with a single dose. This study investigated the effect of food intake and age on NEPA pharmacokinetics (PK) and safety. In this open‐label, single‐center, randomized, phase 1 study, 24 adults (18−45 years) received NEPA in a fed or fasted state during the first treatment period and in the alternative state in the next treatment period. Twelve elderly subjects (≥65 years) received NEPA in a fasted state. Blood samples were taken for netupitant and palonosetron PK analysis. In the fed condition, netupitant plasma exposure increased, whereas palonosetron PK parameters were not affected. Furthermore, elderly subjects showed increased netupitant and palonosetron exposure compared with adults. All adverse events were mild/moderate, with constipation and headache the most common. Although food intake and age altered NEPA PK, dose adjustments were not needed, as netupitant and palonosetron exposure increases did not lead to safety concerns in healthy subjects.
Safety, bioavailability, and pharmacokinetics of VGX‐1027—A novel oral anti‐inflammatory drug in healthy human subjects
Authors: Lee Jessica C. , Menacherry Stanley , Diehl Malissa C. , Giffear Mary D. , White C. Jo , Juba Rob , Bagarazzi Mark L. , Muthumani Karuppiah , Boyer Jean , Agarwal Vipin , Nicoletti Ferdinando , Bart Stephen , Kim J. Joseph , Weiner David B. , Sardesai Niranjan Y. 
Published: April 2015

AbstractVGX‐1027, a novel oral immune modulator, is under development for the treatment of rheumatoid arthritis. The safety, tolerability, and pharmacokinetics of single (1–800 mg) and multiple (40–400 mg) oral doses were evaluated in 2 clinical studies. The doses were well tolerated up to 800 mg in a single dose and 200 mg twice daily in multiple doses. Adverse events were mild to moderate in severity with no identifiable dose‐related pattern. There were no clinically significant physical or laboratory findings. The pharmacokinetic data indicated that increases in Cmax and AUC0−inf were dose‐proportional, and AUC0−τ was approximately dose‐proportional. For the single‐dose study, median Tmax ranged from 0.5 to 2 hours and mean t1/2 ranged from 4.9 to 8.7 hours. For the multiple‐dose study, median Tmax ranged from 0.5 to 2.0 hours and mean t1/2 ranged from 7.05 to 10.05 hours. No accumulation of the drug was observed after day 1, indicating that steady‐state concentrations were attained with single and multiple dosing for 5 days. Approximately 90% of the administered dose was excreted in urine as unchanged drug.
An adaptive energy‐efficient framework for time‐constrained optical backbone networks
Authors: Sarigiannidis Panagiotis , Kakali Vasiliki , Fragakis Manos 
Published: April 2015

SummaryPower management has emerged as a challenge of paramount importance having strong social and financial impact in the community. The rapid growth of information and communication technologies made backbone networks a serious energy consumer. Concurrently, backbone networking is deemed as one of the most promising areas to apply energy efficient frameworks. One of the most popular energy efficient techniques, in the context of backbone networks, is to intentionally switch off nodes and links that are monitored underutilized. Having in mind that optical technology has thoroughly dominated modern backbone networks, the function of switching off techniques entails fast operation and rigorous decision‐making because of the tremendous speed of the underlying optical media. This paper addresses this challenge by introducing a novel, adaptive, and efficient power management scheme for large‐scale backbone networks. The proposed framework exploits traffic patterns and dynamics in order to effectively switch off the set of network entities in a periodic fashion. An adaptive decision‐making algorithm is presented to maximize the network energy gains with respect to time constraints as well as QoS guarantees. The conducted simulation results reveal considerable improvements when applying the proposed framework compared with other inflexible energy efficient schemes. Copyright © 2015 John Wiley & Sons, Ltd.
A distributed adaptive landmark clustering algorithm based on mOverlay and learning automata for topology mismatch problem in unstructured peer‐to‐peer networks
Authors: Saghiri Ali Mohammad , Meybodi Mohammad Reza 
Published: April 2015

SummaryPeer‐to‐peer networks are overlay networks that are built on top of communication networks that are called underlay networks. In these networks, peers are unaware of the underlying networks, so the peers choose their neighbors without considering the underlay positions, and therefore, the resultant overlay network may have mismatches with its underlying network, causing redundant end‐to‐end delay. Landmark clustering algorithms, such as mOverlay, are used to solve topology mismatch problem. In the mOverlay algorithm, the overlay network is formed by clusters in which each cluster has a landmark peer. One of the drawbacks of mOverlay is that the selected landmark peer for each cluster is fixed during the operation of the network. Because of the dynamic nature of peer‐to‐peer networks, using a non‐adaptive landmark selection algorithm may not be appropriate. In this paper, an adaptive landmark clustering algorithm obtained from the combination of mOverlay and learning automata is proposed. Learning automata are used to adaptively select appropriate landmark peers for the clusters in such a way that the total communication delay will be minimized. Simulation results have shown that the proposed algorithm outperforms the existing algorithms with respect to communication delay and average round‐trip time between peers within clusters. Copyright © 2015 John Wiley & Sons, Ltd.
Energy‐efficient multiple‐domain bidirectional scheme for G.hn applications
Authors: Gacanin Haris , Adebisi Bamidele , Ligata Amir 
Published: April 2015

SummaryThis paper presents an energy‐efficient relaying scheme for G.hn standard. We propose a multi‐domain bidirectional communication network with network coding at the physical layer in order to increase network coverage. The logical link control stack was also modified and supplemented with additional functionality. This reduces the power consumption in the network and enhances the performance while reducing collisions for inter‐domain network access. We consider domain selection to minimize the total energy consumption of the network and present optimal power allocation for the given QoS of each end node. Energy efficiency is evaluated in terms of transmit energy per bit for relay networks with bidirectional symmetric and asymmetric traffic flows. Simulation results show that the proposed multi‐domain bidirectional communication provides improved performance and higher energy savings than the single‐domain unidirectional network, especially in powerline communication channel, which is the worst medium of the three G.hn media. Finally, it was demonstrated that improved energy efficiency can be achieved with appropriate domain selection. Copyright © 2015 John Wiley & Sons, Ltd.
Ultra‐Fast Microwave Synthesis of 3D Flower‐Like Co9S8 Hierarchical Architectures for High‐Performance Supercapacitor Applications
Authors: Yin Li , Wang Longqiang , Liu Xiaohong , Gai Yansong , Su Linghao , Qu Baohan , Gong Liangyu 
Published: April 2015

AbstractUltra‐fast microwave irradiation is used to synthesize 3D flower‐like Co9S8 hierarchical architectures. Based on time‐dependent SEM observations, a multistep splitting–growth mechanism is proposed to understand the formation of the observed structures. Moreover, the materials were used as electrodes to fabricate supercapacitors with high specific capacitances of 522, 499, 441, 436, and 397 F g–1 at current densities of 0.5, 0.8,1.0, 1.5, and 2.0 A g–1, respectively. The devices also show high charge–discharge reversibility, with an efficiency of 97.7 % after cycling 1000 times at a current density of 1.0 A g–1.
Palladium‐Catalyzed Direct C–H Arylation of Dicyanobenzenes
Authors: Ihanainen Netta E. , Kumpulainen Esa T. T. , Koskinen Ari M. P. 
Published: April 2015

AbstractA direct palladium‐catalyzed C–H arylation method to synthesize biaryls from dicyanobenzenes has been developed. The reaction is selective towards C2‐arylation of 1,3‐dicyanobenzene and provides biaryls from both electron‐rich and electron‐poor aryl bromides containing para and meta substituents. A variety of functional groups are tolerated, and yields up to 83 % can be obtained. The methodology can be extended to C–H activation of other electron‐deficient benzonitriles.