bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Stereoselective Total Synthesis of 4‐Ketoclonostachydiol (I)
Authors: Rajaram Singanaboina , Ramulu Udugu , Ramesh Dasari , Prabhakar Peddikotla , Venkateswarlu Yenamandra 
Published: March 2014

Abstractinvolving a Horner‐Wadsworth‐Emmons olefination, Grignard reaction, and Hoveyda—Grubbs‐II catalyzed ring closing metathesis as key step
ChemInform Abstract: Depsidones from an Endophytic Fungus Chaetomium sp. Associated with Zanthoxylum leprieurii.
Authors: Talontsi Ferdinand Mouafo , Douanla‐Meli Clovis , Laatsch Hartmut 
Published: March 2014

AbstractChaetosidone A (I), a new depsidone, is isolated from a culture of Chaetomium sp.
ChemInform Abstract: Intramolecular C—C Agostic Complexes: C—C Sigma Interactions by Another Name
Authors: Etienne Michel , Weller Andrew S. 
Published: March 2014

AbstractReview: developments in the synthesis, characterization and reactivity of metal complexes (s‐, d‐ and f‐block) in which a C—C single bond interacts with a metal center; 112 refs.
ChemInform Abstract: What Molecular Assembly Can Learn from Catalytic Chemistry
Authors: Wang Yu , Lin Hai‐Xin , Chen Liang , Ding Song‐Yuan , Lei Zhi‐Chao , Liu De‐Yu , Cao Xiao‐Yu , Liang Hao‐Jun , Jiang Yun‐Bao , Tian Zhong‐Qun 
Published: March 2014

AbstractReview: 136 refs.
Focus on technology: How important is resolution in telecytopathology?
Authors: McMahon Rachel Q. , McCarthy Erin E. , Hetzel Scott J. , Das Kasturi , Stewart Jimmie 
Published: March 2014

BACKGROUNDThe authors conducted an analysis of 2 telepathology systems with different resolutions to determine how resolution affects the pathologists' ability to provide preliminary diagnoses for fine‐needle aspirations (FNA).METHODSFNA cases evaluated by telepathology between February 1, 2011 and January 18, 2012 were reviewed. Concordance indices between preliminary and final diagnoses were calculated for cases assessed with two proprietary systems (the Remote Meeting Technologies iMedHD system and the Olympus NetCam system) using 3 diagnostic classifications (negative, atypical, and suspicious/positive). A Wilcoxon rank‐sum test was used to compare the number of passes necessary to determine adequacy.RESULTSIn total, 298 NetCam cases and 26 iMedHD cases were evaluated. The concordance index, which was calculated using the 3 classifications, was 0.943 (95% confidence interval, 0.922‐0.963) for NetCam compared with 0.951 (95% confidence interval, 0.898‐1.000) for iMedHD. The mean value for the number of passes required to determine adequacy was 2.2 for NetCam and 2.1 for iMedHD (P = .838).CONCLUSIONSThe results from statistical analyses demonstrated no difference in the concordance indices between preliminary and final diagnoses or in the number of passes necessary to render adequacy between the 2 telepathology systems. However, because it had higher resolution along with other features, the iMedHD system achieved greater user satisfaction. Cancer (Cancer Cytopathol) 2014;122:546–552. © 2014 American Cancer Society.
Discovery of biological networks using an optimized partial correlation coefficient with information theory algorithm on Stampede's Xeon and Xeon Phi processors
Authors: Koesterke Lars , Koltes James E. , Weeks Nathan T. , Milfeld Kent , Vaughn Matthew W. , Reecy James M. , Stanzione Dan 
Published: March 2014

SUMMARYThe partial correlation coefficient with information theory (PCIT) method is an important technique for detecting interactions between networks. The PCIT algorithm has been used in the biological context to infer complex regulatory mechanisms and interactions in genetic networks, in genome wide association studies, and in other similar problems. In this work, the PCIT algorithm is re‐implemented with exemplary parallel, vector, input/output (I/O), memory, and instruction optimizations for today's multi‐core and many‐core architectures. The evolution and performance of the new code targets the processor architectures of the Stampede supercomputer but will also benefit other architectures. The Stampede system consists of an Intel Xeon E5 processor base system with an innovative component consist of Intel Xeon Phi Coprocessors. Optimized results and an analysis are presented for both the Xeon and the Xeon Phi. Copyright © 2014 John Wiley & Sons, Ltd.
Generation and correlation algorithms for ternary complementary pairs of sequences of length 3·2n
Authors: Donato P. G. , Hadad M. N. , Funes M. A. , Carrica D. O. 
Published: March 2014

SummaryBinary complementary pairs of sequences, which are available for certain even length values (L = 2n · 10m · 26p), are very interesting for applications with high noise levels and/or highly attenuated signals. To extend the range of useful lengths, some authors have defined ternary complementary pairs of sequences. These sequences have been approached from a theoretical perspective, but further research should be conducted regarding the architectures to process them. This letter describes algorithms for generating and performing the correlation of these sequences using a minimum amount of calculations. These algorithms allow to work with sequences of length 3 · 2n, making it possible to attain a wider range of lengths, and, as a consequence, a wider range of noise immunity in some applications. The proposed approach uses a particular delay arrangement that minimizes the memory requirements in hardware applications. The procedure described could also be used in ternary complementary pairs generated from primitives of length different from 3. Copyright © 2014 John Wiley & Sons, Ltd.
Hexamolybdenum Cluster Complexes with Pyrene and Anthracene Carboxylates: Ultrabright Red Emitters with the Antenna Effect
Authors: Kirakci Kaplan , Fejfarová Karla , Kučeráková Monika , Lang Kamil 
Published: March 2014

AbstractPhosphorescent hexamolybdenum cluster complexes with pyrene and anthracene carboxylates exhibit energy transfer from the grafted ligands to the {Mo6I8} core. The complex with the pyrene ligands exhibits the highest brightness of emission ever reported for a Mo6 cluster complex excited in the near‐UV region (ϵ355 = 2.3 105 M–1 cm–1, ΦL = 0.60). These antenna systems possess attractive features as UV/Red light convertors, optical oxygen sensors, or sensitizers of singlet oxygen.
Regio‐ and Enantioselective Organocascade Michael–Michael Reactions: Construction of Chiral Trisubstituted Indanes
Authors: Li Ning , Liu Guo‐Gui , Chen Jian , Pan Feng‐Feng , Wu Bing , Wang Xing‐Wang 
Published: March 2014

AbstractGiven the importance of indane derivatives in both organic and medicinal chemistry, the development of an effective synthetic protocol for the preparation of multifunctionalized 1,2,3‐trisubstituted indane derivatives is of considerable interest. In this paper, we developed a cascade regio‐ and enantioselective double Michael addition to construct challenging multifunctionalized chiral indane derivatives in the presence of a bifunctional acid–base organocatalyst. The resulting optically active indane derivatives with three alternating trans stereocenters were produced in moderate to good yields with excellent diastereoselectivities and excellent enantioselectivities. Remarkably, the resulting products were facilely converted into multifunctionalized optically active (1‐indanylmethyl)amine and tetrahydroindeno[2,1‐b]pyrrole derivatives.
Living in the north is not necessarily favorable: Different metaphoric associations between cardinal direction and valence in Hong Kong and in the United States
Authors: Huang Yanli , Tse Chi‐Shing , Cho Kit W. 
Published: March 2014

AbstractThe Conceptual Metaphor Theory (e.g., Lakoff & Johnson, ) suggests that people represent abstract concepts in terms of concrete concepts via metaphoric association. Participants in the United States (US) showed that cardinal direction (north/south) is metaphorically associated with valence (positive/negative), as reflected by their estimate for where a person with high or low socioeconomic status (SES) lives in a fictional city or their own living preference (Meier, Moller, Chen, & Riemer‐Peltz, ). The present study tested whether the cardinal direction–valence metaphoric association could be moderated by cultural differences. Although US participants believed that high‐SES and low‐SES individuals were more likely to live in the northern and southern part of the city, respectively, the reverse was so for Hong Kong (HK) participants (Study 1). When asked where they themselves would like to live, HK participants preferred to live in a southern area, whereas US participants showed no preference (Studies 2 and 3). These findings demonstrate cultural differences in metaphoric associations between cardinal direction and valence for HK and US participants. Copyright © 2014 John Wiley & Sons, Ltd.
To help or not to help an outgroup member: The role of the target's individual attributes in resolving potential helpers' motivational conflict
Authors: Siem Birte , Lotz‐Schmitt Katharina , Stürmer Stefan 
Published: March 2014

AbstractWhen people are faced with the decision of whether or not to help an outgroup member, they often experience conflicting motivational tendencies due to the concurrent presence of factors prompting help and factors prompting non‐help. We argue that one way of how people deal with this conflict is by taking a closer look at the target's individual attributes, especially at those indicating the target's benevolence. Findings of Experiment 1 (N = 96), in which we manipulated intercultural dissimilarity between participants and a (fictitious) recipient of help and normative pressure to help as two factors affecting motivational conflict, support this basic assumption. Specifically, response latencies analyses confirmed that participants assigned a culturally highly dissimilar target spent more time on inspecting target‐related information when normative pressure, and thus motivational conflict, was high than when it was low. Experiment 2 (N = 141) extended these findings by demonstrating that providing potential helpers with explicit information about an outgroup member's benevolence increased helping intentions through reducing their negative interaction expectancies (and thus motivational conflict). As expected, this mediational relationship could only be observed for participants assigned a culturally highly dissimilar target. Experiment 3 (N = 46) replicated these mediation findings in a within‐subjects design. Copyright © 2014 John Wiley & Sons, Ltd.
On the significance of crop‐type information for the simulation of catchment hydrology
Authors: Loosvelt Lien , Pauwels Valentijn R. N. , Verhoest Niko E. C. 
Published: March 2014

AbstractSpatially distributed hydrological models require information on the land cover pattern, as it directly influences the generation of run‐off. However, it is not clear which detail of land cover information is suitable for simulating the catchment hydrology. A better understanding of the relationship between the land cover detail and the hydrological processes is therefore required as it would enhance a successful application of the hydrological model. This study investigates the relevance of accurate information about the crop types in the catchment for the simulation of run‐off, baseflow and evapotranspiration. Results reveal that adding knowledge about the crop type in the model simulation is redundant when area‐averaged water flux predictions are intended. On the contrary, when a spatial distribution of water flux predictions is desired, it is meaningful to increase the land cover detail because an increased heterogeneity in the land cover map induces an increased heterogeneity in the hydrological response and locally reduces the uncertainty in the model prediction up to 50%. To assess the land cover uncertainty and to locate the regions for which the reduction in prediction uncertainty is the highest, the thematic uncertainty map (constructed through fuzzy logic) is shown to be a useful tool. Copyright © 2014 John Wiley & Sons, Ltd.
Effects of mindfulness and distraction on pain depend upon individual differences in pain catastrophizing: An experimental study
Authors: Prins B. , Decuypere A. , Van Damme S. 
Published: March 2014

AbstractBackgroundThe aim of this study was to investigate whether the perception of experimental pain was different during a mindfulness manipulation than during a distraction manipulation. Furthermore, it was examined if effects were moderated by dispositional pain catastrophizing.MethodsUndergraduate students (n = 51) completed self‐report measures of pain catastrophizing and mindfulness. Subsequently, they were administered a series of mildly painful heat stimuli, which they had to rate. During pain induction, participants listened to either a pre‐recorded mindfulness instruction (mindfulness group) or a pre‐recorded story (distraction group).ResultsAfter controlling for baseline experimental pain ratings, we found no overall group effect, indicating that there was no difference in experienced pain between the mindfulness group and the distraction group. However, a significant moderation effect was found. When dispositional pain catastrophizing was high, pain was less pronounced in the mindfulness group than in the distraction group, whereas the opposite effect was found when the level of pain catastrophizing was low.ConclusionsThe findings suggest that in persons with a high level of catastrophic thinking about pain, mindfulness‐based coping may be a better approach than distraction.
Advances in vanadate laser crystals at a lasing wavelength of 1 micrometer
Authors: Yu Haohai , Liu Junhai , Zhang Huaijin , Kaminskii Alexander A. , Wang Zhengping , Wang Jiyang 
Published: March 2014

AbstractSapphire, garnet and vanadate crystals are the most prominent optical materials, and vanadates play important roles in optics, especially in lasers and nonlinear optics. Neodymium‐doped yttrium vanadate (Nd:YVO4) is representative and available commercially. Based on Nd:YVO4, several vanadate crystals are being developed with the goal of fulfilling the need for differential applications and improvement of certain operational aspects, such as with pulsed lasers or high‐power continuous‐wave lasers. In recent years, some important effects, including energy enhancement, bistability of output performance, self‐Raman frequency shifting, etc., and some novel applications, such as quantum optics, pulsed lasers modulated by the two‐dimensional crystals, etc., have been discovered with vanadates as gain materials. In this paper, the preparation, characterization and laser applications of vanadate laser crystals at the lasing wavelength of 1 micrometer, including YVO4, GdVO4, LuVO4, GdxY1–xVO4 and LuxGd1–xVO4 (0 < x < 1) doped with Nd3+ and ytterbium (Yb3+) are systematically reviewed by highlighting the most recent research progress. Their specific properties are presented, generation mechanisms of novel physical effects are discussed, new applications are given and possible future applications proposed by focusing on some potential strengths.
Bicriteria scheduling on a single batching machine with job transportation and deterioration considerations
Authors: Tang Lixin , Gong Hua , Liu Jiyin , Li Feng 
Published: March 2014

AbstractWe study a single batching machine scheduling problem with transportation and deterioration considerations arising from steel production. A set of jobs are transported, one at a time, by a vehicle from a holding area to the single batching machine. The machine can process several jobs simultaneously as a batch. The processing time of a job will increase if the duration from the time leaving the holding area to the start of its processing exceeds a given threshold. The time needed to process a batch is the longest of the job processing times in the batch. The problem is to determine the job sequence for transportation and the job batching for processing so as to minimize the makespan and the number of batches. We study four variations (P1, P2, P3, P4) of the problem with different treatments of the two criteria. We prove that all the four variations are strongly NP‐hard and further develop polynomial time algorithms for their special cases. For each of the first three variations, we propose a heuristic algorithm and analyze its worst‐case performance. For P4, which is to find the Pareto frontier, we provide a heuristic algorithm and an exact algorithm based on branch and bound. Computational experiments show that all the heuristic algorithms perform well on randomly generated problem instances, and the exact algorithm for P4 can obtain Pareto optimal schedules for small‐scale instances. © 2014 Wiley Periodicals, Inc. Naval Research Logistics 61: 269–285, 2014
BRAF V600E mutational status in pediatric thyroid cancer
Authors: Henke Lauren E. , Perkins Stephanie M. , Pfeifer John D. , Ma Changquing , Chen Yumei , DeWees Todd , Grigsby Perry W. 
Published: March 2014

AbstractBackgroundClinical outcome of papillary thyroid carcinoma (PTC) in children differs significantly from that of adults. There is no clear explanation of this difference although previous studies have demonstrated a lower prevalence of the BRAFV600E mutation in PTC of children. However, data are limited due to the rarity of this diagnosis. BRAFV600E mutation prevalence and its relationship with outcome in pediatric PTC remain unclear.ProcedureBRAFV600E mutational status was determined in 27 PTC patients less than 22 years of age using restriction fragment length polymorphism (RFLP) analysis. The relationship between BRAFV600E mutation status, patient and tumor characteristics as well as progression‐free survival (PFS) were analyzed.ResultsBRAFV600E was present in 63% of patients and occurred more often in male patients versus females (P = 0.033). Presence of the mutation did not correlate with any difference in extent of disease at diagnosis, tumor size, capsular invasion, vascular invasion, soft tissue invasion, or margin status. At 10 years, PFS for BRAFV600E positive versus negative patients was 55.5% versus 70.0%, respectively (P = 0.48). Overall survival was 100% and median follow‐up was 13.9 years.ConclusionsThis study of pediatric PTC demonstrates that BRAFV600E mutations occur in children at a rate comparable to adults. We found a correlation of BRAFV600E with the male gender, but no evidence that the mutation correlates with more extensive or aggressive disease. This analysis suggests that differences in disease course of PTC in children versus adults are not strongly dependent upon the presence of the BRAFV600E mutation. Pediatr Blood Cancer 2014;61:1168–1172. © 2014 Wiley Periodicals, Inc.
Umbilical artery Doppler at 19 to 22 weeks of gestation in the prediction of adverse pregnancy outcomes
Authors: De Paco Catalina , Ventura Walter , Oliva Raquel , Miguel Myriam , Arteaga Alicia , Nieto Anibal , Delgado Juan L. 
Published: March 2014

ABSTRACTObjectiveThe aim of this study was to determine the clinical utility of Doppler assessment of the umbilical artery in the second trimester scan for predicting adverse pregnancy outcomes.MethodsSingleton pregnancies that had undergone routine anomaly scan at 19 to 22 weeks of gestation with umbilical and uterine artery Doppler measurements. Receiver operating characteristic curves were constructed to evaluate the ability of umbilical artery pulsatility index (PI) to predict small for gestational age and preeclampsia.ResultsThe final study population comprised 4565 singleton pregnancies. Multiple regression analysis showed significant independent contribution of umbilical artery PI in predicting SGA <10th and SGA <5th centiles (adjusted odds ratios of 2.51 and 3.51, respectively). By using a cutoff of umbilical artery PI >90th centile, the likelihood ratio of SGA <5th centile is 2.3 (95% CI: 1.7–3.0).ConclusionsUmbilical artery PI at 19 to 22 weeks of gestation is significantly associated with SGA below the tenth and fifth centiles. A multivariate model combining umbilical and uterine artery Doppler measurements with additional maternal and sonographic characteristics may help predict small for gestational age, particularly those below the fifth centile. © 2014 John Wiley & Sons, Ltd.
Maternal serum analytes as predictors of IUGR with different degrees of placental vascular dysfunction
Authors: Roman Amanda , Desai Neeraj , Krantz David , Liu Hsiao‐Pin , Rosner Jonathan , Vohra Nidhi , Rochelson Burton 
Published: March 2014

ABSTRACTObjectivesOur primary objective was to determine the association of maternal serum analytes in pregnancies complicated by intrauterine growth restriction (IUGR) stratified by umbilical artery (UA) Doppler versus pregnancies with appropriately grown for gestational age (AGA) and its potential use as screening model.MethodsRetrospective cohort evaluating first and second trimester maternal serum aneuploidy screening markers in women complicated with IUGR [90 with absent or reversed end diastolic velocity (AREDV), 46 with UA systolic/diastolic ratio ≥95th percentile and 215 with normal UA Doppler] versus 2590 women with AGA fetuses (control).ResultsExtreme levels of each analyte were significantly more common in the IUGR/AREDV group than in AGA group: inhibin A >97th percentile [≥2.27 multiples of the median (MoM)], OR: 41 (95% CI: 21–80); unconjugated estriol <3rd percentile (≤0.6 MoM), OR: 17.2 (95% CI: 8.1–42); AFP >97th percentile (≥1.88 MoM), OR: 15 (95% CI: 8.2–27); PAPP‐A <3rd percentile (≤0.33 MoM), OR: 13 (95% CI: 6.6–25.5); and free‐beta human chorionic gonadotrophin second trimester >97th percentile (≥3.24 MoM), OR: 11.6 (95% CI: 4.2–32). In a subgroup of pregnancies in which all markers were evaluated on each patient, a combination of abnormal markers detected 73% (95% CI: 54–87%) of IUGR/AREDV fetuses. When maternal risk factors were included into the risk calculation, it increased to 91% (95% CI: 76–98%).ConclusionsAbnormal maternal serum aneuploidy markers preferentially identify those pregnancies at greatest risk of IUGR with AREDV in the UA. © 2014 John Wiley & Sons, Ltd.
Epitope mapping of monoclonal antibodies for the Deinococcus radiodurans bacteriophytochome
Authors: Kim Tae‐Lim , Yoo Jihey , Sangsawang Kanidta , Cho Man‐Ho , Yang Seung Hwan , Suh Joo‐Won , Hahn Tae‐Ryong , Bhoo Seong Hee 
Published: March 2014

AbstractBacteriophytochromes (BphP) are phytochrome‐like light sensing proteins in bacteria, which use biliverdin as a chromophore. In order to study the biochemical properties of the DrBphP protein, five (2B8, 2C11, 3B2, 3D2, and 3H7) anti‐DrBphP monoclonal antibodies were produced through the immunization of mice with purified full‐length DrBphP and DrBphN (1–321 amino acid) proteins, and epitope mapping was then carried out. Among the five antibodies, 2B8 and 2C11 preferentially recognized the N‐terminal region of BphP whereas 3B2, 3D2, and 3H7 showed preference for the C‐terminal region. We performed further epitope mapping using recombinant truncated BphP proteins to narrow down their target sequences. The results demonstrated that each of the five monoclonal antibodies recognized different regions on the DrBphP protein. Additionally, epitopes of 2B8 and 3H7 antibodies were discovered to be shorter than 10 amino acids (2B8: RDPLPFFPP, 3H7: PGEIEEA). These two antibodies with such specific recognition epitopes could be especially valuable for developing new peptide tags for protein detection and purification.