bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pendampingan Remaja Melalui Edukasi Kesehatan Reproduksi di SMP Satap Molobog Kabupaten Bolaang Mongondow Timur
Authors: Wahyuni Wahyuni , Fajrin Irmasanti , Solang Sesca Diana 
Published: July 2024

ABSTRAK Asuhan kesehatan reproduksi sangat penting bagi remaja, yang mencakup 16% dari populasi global, namun banyak yang belum terpenuhi kebutuhannya. Mereka sering menghadapi hambatan seperti kurangnya pengetahuan dan akses ke layanan kesehatan. Kebijakan perlu ditingkatkan untuk memberikan edukasi dan layanan kesehatan reproduksi yang aman, akurat, dan terjangkau. Tujuan kegiatan ini yaitu untuk meningkatkan pengetahuan dan pemahaman remaja tentang kesehatan reproduksi. Metode yang digunakan adalah edukasi terstruktur melalui ceramah dan tanya jawab tentang kesehatan reproduksi selama ± 60 menit. Hasil pengabdian menunjukkan peningkatan signifikan pengetahuan remaja tentang kesehatan reproduksi. Sebelumnya, skor pengetahuan berkisar antara 39 hingga 72, dengan rata-rata 53. Setelah mendapat edukasi, skor pengetahuan meningkat menjadi 61 hingga 89, dengan rata-rata 76. Berdasarkan kategori, sebelum pemberian edukasi, sebagian besar remaja (78%) memiliki pengetahuan yang kurang tentang kesehatan reproduksi. Setelah edukasi, mayoritas (58%) telah memperoleh pengetahuan yang baik tentang kesehatan reproduksi. Dapat disimpulkan bahwa dengan pendampingan berupa pemberian edukasi secara terstruktur dapat meningkatkan pemahaman remaja tentang kesehatan reproduksi secara signifikan. Kata kunci: Edukasi Remaja, Kesehatan Reproduksi ABSTRACT Reproductive health care is critical for adolescents, who make up 16% of the global population, but many have unmet needs. They often face barriers such as lack of knowledge and access to health services. Policies need to be improved to provide safe, accurate and affordable reproductive health education and services. The aim of this activity is to increase teenagers' knowledge and understanding of reproductive health. The method used is structured education through lectures and questions and answers about reproductive health for ± 60 minutes. The results of the service show a significant increase in teenagers' knowledge about reproductive health. Previously, knowledge scores ranged from 39 to 72, with an average of 53. After receiving education, knowledge scores increased to 61 to 89, with an average of 76. Based on category, before providing education, the majority of teenagers (78%) had knowledge less about reproductive health. After education, the majority (58%) have gained good knowledge about reproductive health. It can be concluded that assistance in the form of providing structured education can significantly increase teenagers' understanding of reproductive health. Keywords : Adolescent Education, Reproductive Health
Optimalisasi Peran Kader dalam Melakukan Latihan Fungsional Pasien Post Stroke di Desa Gisikcemandi Sidoarjo
Authors: Prastyawati Irine Yunila , Pramono Dominggus Ruku Yudit , Yuliati Ignata , Kurniawaty Yuni , Dwianto Ignatius Heri 
Published: July 2024

ABSTRAK Kader memiliki kontribusi dalam optimalisasi fungsional pasien post stroke, agar pasien mampu meningkatkan derajat kesehatan serta kemandirian pasien. Tujuan kegiatan ini adalah meningkatkan keterampilan kader untuk membantu memberikan tindakan latihan fungsional kepaada pasien. Metode yang dilakukan metode partisipatoris Participatory Rural Apraissal (PRA). Pelaksanaan kegiatan pengabdian kepada masyarakat diawali dengan perijinan kepada Kepala Desa Gisikcemandi, koordinasi dengan mitra, pembagian tugas diantara tim pelaksana. Partisipasi mitra dilakukan dengan mempersiapkan tempat dan alat pengeras suara. Proses diskusi lancar, mitra memperhatikan penjelasan, beberapa pertanyaan diajukan kepada tim pelaksana. Hasil terdapat peningkatan keterampilan mitra tentang latihan fungsional pada stroke dengan tingkat keterampilan baik setelah diberikan pelatihan kesehatan kepada mitra. Diharapkan dengan adanya peningkatan keterampilan latihan fungsional pada kader, terjadi perubahan perilaku menolong yang lebih spesifik khususnya pada bidang latihan fungsional. Kata Kunci: Optimalisasi, Kader, Stroke ABSTRACT Cadres have a contribution in optimizing the functional function of post-stroke patients, so that patients are able to improve the patient's level of health and independence. The aim of this activity is to improve the skills of cadres to help provide functional training procedures to patients. The method used is the Participatory Rural Appraisal (PRA) method. Implementation of community service activities begins with permission from the Gisikcemandi Village Head, coordination with partners, division of tasks between the implementing team. Partner participation is carried out by preparing a place and loudspeakers. The discussion process was smooth, partners paid attention to the explanation, several questions were asked to the implementing team. The results showed an increase in partners' skills regarding functional training for stroke with good skill levels after health training was provided to partners. It is hoped that by increasing functional training skills in cadres, there will be changes in more specific helping behavior, especially in the area of functional training. Keywords: Optimization, Community Health Workers, Stroke
Peningkatan Pengetahuan Masyarakat dalam Pemanfaatan dan Pemilihan Bahan Baku Obat Tradisional di Daerah Cikatomas Kabupaten Tasikmalaya
Authors: Nurdianti Lusi , Rahayuningsih Nur , Wulandari Winda Trisna , Aprillia Ade Yeni , Idacahyati Keni , Indra Indra , Wardani Gatut Ari , Setiawan Fajar , Gustaman Firman , Annissya Widia Primi , Julyanti Ai Rian 
Published: July 2024

ABSTRAK Masyarakat daerah Cikatomas Kabupaten Tasikmalaya mata pencaharian utamanya adalah sebagai petani, sehingga tanaman tumbuh baik disana, pemanfaatan tanaman ini dapat dibuat untuk bahan baku jamu sehingga dapat memberdayakan dan mendorong masyarakat dalam upaya pengembangan kesehatan tradisional. Memberdayakan masyarakat dengan pengetahuan dan keterampilan dalam mengolah tanaman obat menjadi produk jamu yang bermanfaat bagi Kesehatan selain itu untuk meningkatkan kesadaran masyarakat tentang pentingnya memilih jamu yang aman dan memiliki izin edar dari BPOM serta mengembangkan potensi ekonomi lokal melalui usaha home industry berbasis produk jamu. Total peserta yang termasuk dalam kriteria inkulusi dalam kegiatan ini adalah 110 orang, penyuluhan yang dilakukan menggunakan metode presentasi dengan media spanduk, stiker, dan power point, selain itu dilakukan pretest dan post-test. Rata-rata pretest sebesar 58,41 dan post-test sebesar 92,95, berdasarkan hasil pengujian statistik nilai pretest dengan post-test memiliki perbedaan yang signifikan (p<0,05). Program penyuluhan pemanfaatan Bahan Baku Obat Tradisional dalam pembuatan sediaan jamu dan cerdas memilih obat tradisional di Kampung Parunggolong desa Lengkong Barang kecamatan Cikatomas Kabupaten Tasikmalaya mendapatkan respon yang positif dari masyarakat setempat. Kata Kunci: Obat Tradisional, Jamu, Cikatomas ABSTRACT The people of the Cikatomas area in Tasikmalaya Regency primarily earn their livelihood as farmers. The plants grown there are well-suited for use as raw materials in herbal medicines. Utilizing these plants can empower and encourage the community in their efforts to develop traditional health practices. Empowering the community with knowledge and skills to process medicinal plants into beneficial herbal products not only increases public awareness about the importance of selecting herbal medicines that are safe and approved by BPOM but also helps develop local economic potential through home-based businesses centered around herbal medicine products. A total of 110 participants met the inclusion criteria for this activity. The counseling was conducted using presentations with banners, stickers, and PowerPoint. Additionally, a pretest and post-test were administered. The pretest average score was 58.41, while the post-test average was 92.95. Based on statistical testing, there is a significant difference between the pretest and post-test scores (p < 0.05). The outreach program focused on the use of traditional medicinal raw materials for making herbal medicine preparations and smart selection of traditional medicines in Parunggolong Village, Lengkong Barang Village, Cikatomas District, Tasikmalaya Regency, was well-received by the local community. Keywords: Traditional Medicine, Jammu, Cikatomas
Faktor-Faktor yang Berhubungan dengan Pencapaian Pemberian ASI Eksklusif di Praktik Mandiri Bidan Cut Nurasma
Authors: Siregar Elvina Rizki , Pasaribu Friska Yanti , Waruwu Febriati , Sari Hesti Kumala , Taringan Pebriani Br. , Paninsari Debora 
Published: July 2024

ABSTRACT Exclusive breast milk is very important for a child's survival to protect against various diseases that are highly susceptible to nature and which can be fatal for the baby. Such as diarrhea & pneumonia. There is a lot of evidence that shows that mothers who exclusively breastfeed their babies can have higher dominant intelligence when compared with babies who do not receive exclusive breast milk from their mothers. In addition, babies who are breastfed have a lower chance of becoming obese and also experiencing DM (Diabetes Mellitus). To determine the internal and external factors related to the successful achievement of providing Exclusive Breast Milk by Midwife Cut Nurasma's Independent Practice. This research uses a type of quantitative research, namely an analytical survey with a cross-sectional research design carried out by interviews and distributing questionnaires to determine the factors in achieving exclusive breastfeeding. Based on the analysis of the chi-square test results on husband's support & knowledge, it shows a p-value of 0.000, on family support it shows a p-value of 0.036 and on mother's attitude it shows a p-value of 0.010, which means <0.05 so Ho rejected and Ha accepted. Conclusion: the researcher can conclude that there are success factors in achieving exclusive breastfeeding. Keywords: Factors, Achievement, Exclusive Breastfeeding ABSTRAK ASI Eksklusif sangat penting diberikan bagi kelangsungan hidup seorang anak untuk melindungi dari macam-macam penyakit yang sangat rentan di alami serta yang dapat berakibat fatal bagi bayi. Sepertidiare & pneumonia. Sudah banyak bukti yang memperlihatkan bahwa ibu yang menjalankan ASI Eksklusif kepada bayi nya, bayi dapat memiliki kecerdasan yang dominan lebih tinggi ketika kita bandingkan dengan bayi yang tidakmendapatkan ASI Eksklusif dari sang ibu. Selain itu, Bayi yang diberi ASI memiliki kemungkinan lebih rendah mengalami obesitas dan juga mengalami DM (Diabetes Melitus). Untuk mengetahui faktor internal dan eksternal yang berhubungan dengan keberhasilan pencapaian pemberian Asi Eksklusif Praktik Mandiri Bidan Cut Nurasma. Penelitian ini menggunakan jenis penelitian kuantitatif yaitu survey analitik dengan desain penelitian yang digunakan adalah cross-sectional yang dilaksanakan dengan wawancara danpenyebaran kuesioner untuk mengetahui faktor- faktor dalam pencapaian pemberian asi eksklusif. Hasil: Berdasarkan Analisis hasil uji chi-square pada dukungan suami & pengetahuan menunjukkan nilai p-value sebesar 0,000, padadukungan keluarga menunjukkan nilai p-value sebesar 0,036 dan pada sikap ibu menunjukkan nilai p-value sebesar 0,010 yang berarti<0,05 sehingga Ho ditolakdan Ha diterima. maka peneliti dapat menyimpulkan bahwa adanya faktor-faktor keberhasilan dalam pencapaian pemberian ASI Eksklusif. Kata Kunci: Faktor-Faktor, Pencapaian, ASI Eksklusif
Noise sensitivity and its associated factors among the students of Rajshahi City in Bangladesh: A cross-sectional study
Authors: Sarker Pramath Chandra , Ullah Md. Nayamat , Morshed Fahim , Sultana Sabina , Siddique Md. Nur-E-Alam 
Published: July 2024

Background: Noise pollution is an important environmental problem with far-reaching and unavoidable consequences. The present study aimed to identify noise sensitivity and its associated factors among students of Rajshahi City.
Methods: A total of 473 respondents were selected conveniently from five educational institutions in Rajshahi City. Among them, 273 were women, and 200 were men aged 18 to 28 (mean, 22.9). The Bangla version of the Noise Sensitivity Scale was administered to measure the participants' noise sensitivity level.
Results: Noise sensitivity varied significantly with sleep duration, anger toward noise polluters, level of noise annoyance, and the avoidance of noise-polluted roads (using alternative roads) among the respondents. There was no significant effect of sex or residence in a noise-polluted area on noise sensitivity. The results also indicate that anger at polluters and noise annoyance strongly influence noise sensitivity.
Conclusion: Noise sensitivity affects many aspects of human life. These findings will assist policymakers, and urban planners mitigate the harmful effects of noise sensitivity on human health.
Perancangan Keputusan Cut Off Baterai ROV menggunakan Metode Decision Tree
Authors: Zhafirah Talitha Amalia , Agus Khumaidi  , Zindhu Maulana Ahmad Putra  , Dwi Sasmita Aji Pambudi  , Ryan Yudha Adhitya  , Didik Sukoco  
Published: July 2024

Dalam beberapa dekade terakhir, teknologi transportasi bawah air telah berkembang pesat, ditandai dengan munculnya berbagai jenis kendaraan bawah air yang semakin canggih, termasuk Remotely Operated Vehicle (ROV). ROV menggunakan baterai sebagai sumber energi karena sifatnya yang portabel dan efisien. Baterai ROV memerlukan sistem proteksi bayerai yang efisien untuk mencegah kerusakan serta memperpanjang masa pakai baterai. Dengan ini, metode decision tree diterapkan dalam perancangan keputusan cut off baterai ROV. Pengambilan keputusan ditentukan oleh nilai arus dan tegangan yang dibaca oleh sensor INA219. Dalan decision tree, nilai gain terbesar dijadikan node utama atau root node. Dalam penelitian ini nilai gain yang diperoleh sama besar akibat dataset yang seimbang, data pertama dipilih sebagai root node berdasarkan prinsip Occam's Razor untuk kesederhanaan. Sehingga nilai dari sensor 1 akan dijadikan node utama atau root node. Perancangan keputusan cut off baterai ROV menggunakan metode decision tree memberikan hasil yang efektif dan efisien dalam pengendalian daya baterai ROV
Modulation of arterial intima stiffness by disturbed blood flow
Authors: Bywaters Briana C. , Trache Andreea , Rivera Gonzalo M. 
Published: July 2024

The intima, comprising the endothelium and the subendothelial matrix, plays a crucial role in atherosclerosis pathogenesis. The mechanical stress arising from disturbed blood flow (d-flow) and the stiffening of the arterial wall contributes to endothelial dysfunction. However, the specific impacts of these physical forces on the mechanical environment of the intima remain undetermined. Here, we investigated whether inhibiting collagen crosslinking could ameliorate the detrimental effects of persistent d-flow on the mechanical properties of the intima. Partial ligation of the left carotid artery (LCA) was performed in C57BL/6J mice, inducing d-flow. The right carotid artery (RCA) served as an internal control. Carotids were collected 2 days and 2 weeks after surgery to study acute and chronic effects of d-flow on the mechanical phenotype of the intima. The chronic effects of d-flow were decoupled from the ensuing arterial wall stiffening by administration of β-aminopropionitrile (BAPN), an inhibitor of collagen crosslinking by lysyl oxidase (LOX) enzymes. Atomic force microscopy (AFM) was used to determine stiffness of the endothelium and the denuded subendothelial matrix in en face carotid preparations. The stiffness of human aortic endothelial cells (HAEC) cultured on soft and stiff hydrogels was also determined. Acute exposure to d-flow caused a slight decrease in endothelial stiffness in male mice but had no effect on the stiffness of the subendothelial matrix in either sex. Regardless of sex, the intact endothelium was softer than the subendothelial matrix. In contrast, exposure to chronic d-flow led to a substantial increase in the endothelial and subendothelial stiffness in both sexes. The effects of chronic d-flow were largely prevented by concurrent BAPN administration. In addition, HAEC displayed reduced stiffness when cultured on soft vs. stiff hydrogels. We conclude that chronic d-flow results in marked stiffening of the arterial intima, which can be effectively prevented by inhibition of collagen crosslinking.
Development of polyvinyl alcohol nanofiber scaffolds loaded with flaxseed extract for bone regeneration: phytochemicals, cell proliferation, adhesion, and osteogenic gene expression
Authors: Abdelaziz Ahmed G. , Nageh Hassan , Abdalla Mohga S. , Abdo Sara M. , Amer Asmaa A. , Loutfy Samah A. , Abdel Fattah Nasra F. , Alsalme Ali , Cornu David , Bechelany Mikhael , Barhoum Ahmed 
Published: July 2024

Introduction: Bone tissue engineering seeks innovative materials that support cell growth and regeneration. Electrospun nanofibers, with their high surface area and tunable properties, serve as promising scaffolds. This study explores the incorporation of flaxseed extract, rich in polyphenolic compounds, into polyvinyl alcohol (PVA) nanofibers to improve their application in bone tissue engineering.Methods: High-performance liquid chromatography (HPLC) identified ten key compounds in flaxseed extract, including polyphenolic acids and flavonoids. PVA nanofibers were fabricated with 30 wt.% flaxseed extract (P70/E30) via electrospinning. We optimized characteristics like diameter, hydrophilicity, swelling behavior, and hydrolytic degradation. MG-63 osteoblast cultures were used to assess scaffold efficacy through cell adhesion, proliferation, viability (MTT assay), and differentiation. RT-qPCR measured expression of osteogenic genes RUNX2, COL1A1, and OCN.Results: Flaxseed extract increased nanofiber diameter from 252 nm (pure PVA) to 435 nm (P70/E30). P70/E30 nanofibers showed higher cell viability (102.6% vs. 74.5% for pure PVA), although adhesion decreased (151 vs. 206 cells/section). Notably, P70/E30 enhanced osteoblast differentiation, significantly upregulating RUNX2, COL1A1, and OCN genes.Discussion: Flaxseed extract incorporation into PVA nanofibers enhances bone tissue engineering by boosting osteoblast proliferation and differentiation, despite reduced adhesion. These properties suggest P70/E30’s potential for regenerative medicine, emphasizing scaffold optimization for biomedical applications.
Direct comparison of whole heart quantifications between different retrospective and prospective gated 4D flow CMR acquisitions
Authors: Fischer Kady , Grob Leonard , Setz Louis , Jung Bernd , Neuenschwander Mario D. , Utz Christoph D. , von Tengg-Kobligk Hendrik , Huber Adrian T. , Friess Jan O. , Guensch Dominik P. 
Published: July 2024

Introduction4D flow cardiovascular magnetic resonance (CMR) is a versatile technique to non-invasively assess cardiovascular hemodynamics. With developing technology, choice in sequences and acquisition parameters is expanding and it is important to assess if data acquired with these different variants can be directly compared, especially when combining datasets within research studies. For example, sequences may allow a choice in gating techniques or be limited to one method, yet there is not a direct comparison investigating how gating selection impacts quantifications of the great vessels, semilunar and atrioventricular valves and ventricles. Thus, this study investigated if quantifications across the heart from contemporary 4D flow sequences are comparable between two commonly used 4D flow sequences reliant on different ECG gating techniques.MethodsForty participants (33 healthy controls, seven patients with coronary artery disease and abnormal diastolic function) were prospectively recruited into a single-centre observational study to undergo a 3T-CMR exam. Two acquisitions, a k-t GRAPPA 4D flow with prospective gating (4Dprosp) and a modern compressed sensing 4D flow with retrospective gating (4Dretro), were acquired in each participant. Images were analyzed for volumes, flow rates and velocities in the vessels and four valves, and for biventricular kinetic energy and flow components. Data was compared for group differences with paired t-tests and for agreement with Bland-Altman and intraclass correlation (ICC).ResultsMeasurements primarily occurring during systole of the great vessels, semilunar valves and both left and right ventricles did not differ between acquisition types (p &gt; 0.05 from t-test) and yielded good to excellent agreement (ICC: 0.75–0.99). Similar findings were observed for the majority of parameters dependent on early diastole. However, measurements occurring in late diastole or those reliant on the entire-cardiac cycle such as flow component volumes along with diastolic kinetic energy values were not similar between 4Dprosp and 4Dretro acquisitions resulting in poor agreement (ICC &lt; 0.50).DiscussionDirect comparison of measurements between two different 4D flow acquisitions reliant on different gating methods demonstrated systolic and early diastolic markers across the heart should be compatible when comparing these two 4D flow sequences. On the other hand, late diastolic and intraventricular parameters should be compared with caution.
Exploring galectin-3’s role in predicting mild cognitive impairment in type 2 diabetes and its regulation by miRNAs
Authors: Zhou Xueling , Dai Ning , Yu Dandan , Niu Tong , Wang Shaohua 
Published: July 2024

ObjectiveThis study aimed to investigate the role of galectin-3 (Gal-3; coded by LGALS3 gene), as a biomarker for MCI in T2DM patients and to develop and validate a predictive nomogram integrating galectin-3 with clinical risk factors for MCI prediction. Additionally, microRNA regulation of LGALS3 was explored.MethodsThe study employed a cross-sectional design. A total of 329 hospitalized T2DM patients were recruited and randomly allocated into a training cohort (n = 231) and a validation cohort (n = 98) using 7:3 ratio. Demographic data and neuropsychological assessments were recorded for all participants. Plasma levels of galectin-3 were measured using ELISA assay. We employed Spearman’s correlation and multivariable linear regression to analyze the relationship between galectin-3 levels and cognitive performance. Furthermore, univariate and multivariate logistic regression analyses were conducted to identify independent risk factors for MCI in T2DM patients. Based on these analyses, a predictive nomogram incorporating galectin-3 and clinical predictors was developed. The model’s performance was evaluated in terms of discrimination, calibration, and clinical utility. Regulatory miRNAs were identified using bioinformatics and their interactions with LGALS3 were confirmed through qRT-PCR and luciferase reporter assays.ResultsGalectin-3 was identified as an independent risk factor for MCI, with significant correlations to cognitive decline in T2DM patients. The developed nomogram, incorporating Gal-3, age, and education levels, demonstrated excellent predictive performance with an AUC of 0.813 in the training cohort and 0.775 in the validation cohort. The model outperformed the baseline galectin-3 model and showed a higher net benefit in clinical decision-making. Hsa-miR-128-3p was significantly downregulated in MCI patients, correlating with increased Gal-3 levels, while Luciferase assays confirmed miR-128-3p’s specific binding and influence on LGALS3.ConclusionOur findings emphasize the utility of Gal-3 as a viable biomarker for early detection of MCI in T2DM patients. The validated nomogram offers a practical tool for clinical decision-making, facilitating early interventions to potentially delay the progression of cognitive impairment. Additionally, further research on miRNA128’s regulation of Gal-3 levels is essential to substantiate our results.