bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cell Adhesion Molecules and Stem Cell-Niche-Interactions in the Limbal Stem Cell Niche
Authors: Polisetti Naresh , Zenkel Matthias , Menzel-Severing Johannes , Kruse Friedrich E. , Schlötzer-Schrehardt Ursula 
Published: September 2015

Abstract
Interactions between stem cells and their microenvironment are critical for regulation and maintenance of stem cell function. To elucidate the molecular interactions within the human limbal epithelial stem/progenitor cell (LEPC) niche, which is essential for maintaining corneal transparency and vision, we performed a comprehensive expression analysis of cell adhesion molecules (CAMs) using custom-made quantitative real-time polymerase chain reaction (qRT-PCR) arrays and laser capture-microdissected LEPC clusters, comprising LEPCs, melanocytes, mesenchymal cells, and transmigrating immune cells. We show that LEPCs are anchored to their supporting basement membrane by the laminin receptors α3β1 and α6β4 integrin and the dystroglycan complex, while intercellular contacts between LEPCs and melanocytes are mediated by N-, P-, and E-cadherin together with L1-CAM, a member of the immunoglobulin superfamily (Ig)CAMs. In addition to the LEPC-associated heparan sulfate proteoglycans syndecan-2, glypican-3, and glypican-4, the IgCAM members ICAM-1 and VCAM-1 were found to be variably expressed on LEPCs and associated niche cells and to be dynamically regulated in response to chemokines such as interferon-γ to enhance interactions with immune cells. Moreover, junctional adhesion molecule JAM-C accumulating in the subepithelial limbal matrix, appeared to be involved in recruitment of immune cells, while mesenchymal stromal cells appeared to use the nephronectin receptor integrin α8 for approaching the limbal basement membrane. In summary, we identified a novel combination of cell surface receptors that may regulate both stable and dynamic cell-matrix and cell–cell interactions within the limbal niche. The findings provide a solid foundation for further functional studies and for advancement of our current therapeutic strategies for ocular surface reconstruction.
Synthesis, Characterization, and Crystal Structure of a Polymeric Copper(II) Complex Derived from 2‐(5‐Chloro‐2‐hydroxybenzylideneamino)‐2‐ethylpropane‐1,3‐diol with Catalytic Oxidation Property
Authors: Wang Ning 
Published: September 2015

AbstractThe copper(II) complex [Cu2L2(μ1,3‐NCS)2]n·nMeOH [HL = 2‐(5‐chloro‐2‐hydroxybenzylideneamino)‐2‐ethylpropane‐1,3‐diol] was synthesized and characterized by elemental analysis, as well as FT‐IR, and UV/Vis spectroscopy. The structures of the ligand and the complex were confirmed by single‐crystal X‐ray diffraction analyses. The Schiff base ligand coordinates to the copper atoms through the phenolate oxygen and imino nitrogen atoms, and one hydroxyl oxygen atom. The copper atoms are in octahedral coordination. The complex is an active catalyst for the oxidation of cyclooctene and styrene with tert‐butylhydroperoxide as the oxidant under mild conditions.
Improved Synthesis and Detailed Characterization of a Hybrid Pyrazole‐TACN Dinucleating Ligand
Authors: Dalle Kristian Erwin , Dechert Sebastian , Meyer Franc 
Published: September 2015

AbstractAn improved synthetic procedure is reported for the hybrid ligand HL, composed of two TACN macrocycles bridged by a central pyrazole moiety. Detailed NMR spectroscopic characterization showed that asymmetry in this dinucleating organic scaffold can be induced at room temperature through the use of anhydrous conditions, owing to pyrazole‐NH prototropy. Thermally induced line broadening allowed for an estimation of the thermodynamic parameters for this proton exchange reaction, giving ΔH‡ = 46.7 kJ·mol–1 and ΔS‡ = –74.2 J·mol–1·K–1. Crystallization of a key intermediate is a crucial aspect of the synthetic improvement, characterization of which revealed an intramolecular hydrogen bond between a sidearm heteroatom and the pyrazole‐NH proton. Protonation of the macrocyclic sidearms in [H3L](BF4)2 allowed for exploration of the influence that this interaction has on the tautomerism, which may in turn potentially be exploited to produce heterobimetallic systems. Structural characterization of the corresponding sodium salt NaL gave further insights into the general coordination behavior of HL.
Qualitative and quantitative analysis of solar hydrogen generation literature from 2001 to 2014
Authors: Maghami Mohammad Reza , asl Shahin navabi , Rezadad Mohammad esmaeil , Ale Ebrahim Nader , Gomes Chandima 
Published: September 2015

Abstract
Solar hydrogen generation is one of the new topics in the field of renewable energy. Recently, the rate of investigation about hydrogen generation is growing dramatically in many countries. Many studies have been done about hydrogen generation from natural resources such as wind, solar, coal etc. In this work we evaluated global scientific production of solar hydrogen generation papers from 2001 to 2014 in any journal of all the subject categories of the Science Citation Index compiled by Institute for Scientific Information (ISI), Philadelphia, USA. Solar hydrogen generation was used as keywords to search the parts of titles, abstracts, or keywords. The published output analysis showed that hydrogen generation from the sun research steadily increased over the past 14 years and the annual paper production in 2013 was about three times 2010-paper production. The number of papers considered in this research is 141 which have been published from 2001 to this date. There are clear distinctions among author keywords used in publications from the five most high-publishing countries such as USA, China, Australia, Germany and India in solar hydrogen studies. In order to evaluate this work quantitative and qualitative analysis methods were used to the development of global scientific production in a specific research field. The analytical results eventually provide several key findings and consider the overview hydrogen production according to the solar hydrogen generation.
General practitioner reported incidence of Lyme carditis in the Netherlands
Authors: Hofhuis A. , Arend S.M. , Davids C.J. , Tukkie R. , van Pelt W. 
Published: September 2015

Abstract

Background
Between 1994 and 2009, incidence rates of general practitioner (GP) consultations for tick bites and erythema migrans, the most common early manifestation of Lyme borreliosis, have increased substantially in the Netherlands. The current article aims to estimate and validate the incidence of GP-reported Lyme carditis in the Netherlands.

Methods
We sent a questionnaire to all GPs in the Netherlands on clinical diagnoses of Lyme borreliosis in 2009 and 2010. To validate and adjust the obtained incidence rate, medical records of cases of Lyme carditis reported by GPs in this incidence survey were reviewed and categorised according to likelihood of the diagnosis of Lyme carditis.

Results
Lyme carditis occurred in 0.2 % of all patients with GP-reported Lyme borreliosis. The adjusted annual incidence was six GP-reported cases of Lyme carditis per 10 million inhabitants, i.e. approximately ten cases per year in 2009 and 2010.

Conclusions
We report the first incidence estimate for Lyme carditis in the Netherlands, validated by a systematic review of the medical records. Although Lyme carditis is an uncommon manifestation of Lyme borreliosis, physicians need to be aware of this diagnosis, in particular in countries where the incidence of Lyme borreliosis has increased during the past decades.
Performance of the Visual-Motor Integration of Preschool Children in Hong Kong
Authors: Ng Miranda , Chui Mandy , Lin Lenzs , Fong Anita , Chan Donna 
Published: September 2015

Objective/Background The Beery–-Buktenica Developmental Test of Visual-Motor Integration (VMI) is an important assessment tool used by occupational therapists working with children. The aims of this study were (a) to identify performance differences in the VMI between Hong Kong preschool children and their counterparts in the United States; (b) to develop local references for the VMI (fifth edition) for the preschool children in Hong Kong; and (c) to examine the dimensionality and the hierarchical ordering of the VMI items using the Rasch Measurement Model (RMM). Methods A total of 288 healthy children aged between 3 years and 6 months and 5 years and 11 months were recruited from 54 local preschools in Hong Kong using the multistage sampling method. VMI was administered to the children individually at their preschools. Results Hong Kong preschool children were significantly better than those in the United States in VMI performance (p < .001). The results of the RMM showed that the VMI fell within the acceptable levels of unidimensionality. Most items were found to be hierarchically ordered, although a few items were found to have the same level of difficulty. Conclusion The local reference developed in this study yielded additional insights for occupational therapists and psychologists with regard to the application of the VMI (fifth edition) for Hong Kong children aged between 3 years and 6 months and 5 years and 11 months.
Delays and barriers to care in Colombia among women obtaining legal first‐ and second‐trimester abortion
Authors: Baum Sarah , DePiñeres Teresa , Grossman Daniel 
Published: September 2015

AbstractObjectiveTo evaluate delays before first‐ or second‐trimester legal abortion and barriers to care in Colombia.MethodsA secondary analysis was undertaken of data from a prospective cohort study of women undergoing first‐trimester (< 12 weeks) and second‐trimester (12–15 weeks) abortion between February and July 2012. Participants (aged ≥ 18 years with access to a telephone) reported key dates in their abortion process and barriers to care. Univariate and multivariate analyses were performed.ResultsOverall, 100 women in the first trimester and 200 in the second trimester were included. Second‐trimester clients experienced longer delays in each step of the abortion process than did first‐trimester clients (P < 0.001 for all three intervals examined), with the largest delay being time to suspicion of pregnancy (37 days vs 17 days). Difficulty accessing care was associated with the second trimester (odds ratio 5.1, 95% CI 2.9–9.1) and low socioeconomic status (odds ratio 2.3, 95% CI 1.2–4.3). Financial barriers were the most common (30 [30.0%] first‐trimester clients; 86 [43.0%] second‐trimester clients).ConclusionDespite partial decriminalization of abortion in 2006, Colombian women still face barriers to legal services that probably contribute to late presentation. Interventions promoting early pregnancy recognition and information about how to access legal abortion could reduce the need for second‐trimester services.
Trajectories of decline in cognition and daily functioning in preclinical dementia
Authors: Verlinden Vincentius J.A. , van der Geest Jos N. , de Bruijn Renée F.A.G. , Hofman Albert , Koudstaal Peter J. , Ikram M. Arfan 
Published: September 2015

AbstractIntroductionAlthough preclinical dementia is characterized by decline in cognition and daily functioning, little is known on their temporal sequence. We investigated trajectories of cognition and daily functioning in preclinical dementia, during 18 years of follow‐up.MethodsIn 856 dementia cases and 1712 controls, we repetitively assessed cognition and daily functioning with memory complaints, mini‐mental state examination (MMSE), instrumental activities of daily living (IADL), and basic activities of daily living (BADL).ResultsDementia cases first reported memory complaints 16 years before diagnosis, followed by decline in MMSE, IADL, and finally BADL. Vascular dementia related to earlier decline in daily functioning but later in cognition, compared with Alzheimer's disease. Higher education related to larger preclinical cognitive decline, whereas apolipoprotein E (APOE) ε4 carriers declined less in daily functioning.DiscussionThese results emphasize the long hierarchical preclinical trajectory of functional decline in dementia. Furthermore, they show that various pathologic, environmental, and genetic factors may influence these trajectories of decline.
CAPITAL TAXES, LABOR TAXES AND THE HOUSEHOLD
Authors: Oikonomou Rigas , Siegel Christian 
Published: September 2015

Abstract:We study the impact of capital and labor taxation in an economy where couples bargain over the intrahousehold allocation under limited commitment. In this framework more wealth improves commitment and gives rise to insurance gains within the household. Our theory motivates these gains by the empirical observation that wealth, in contrast to labor income, is a commonly held resource within households. Based on this observation we study whether eliminating capital taxes from the economy, and raising labor taxes to balance the government’s budget, may generate welfare gains to married households. We illustrate that the quantitative effects from this reform are rather small. We attribute the small effects to the life cycle pattern of wealth accumulation and to the impact of labor income taxes on household risk sharing: In particular, we show that higher labor taxes may make the limited commitment friction more severe, even though they may make the distribution of labor income more equitable within the household.
Fair Revaluation of Wine as an Investment
Authors: Bocart Fabian Y.R.P. , Hafner Christian M. 
Published: September 2015

AbstractThe price of wine is a key topic among market participants interested in valuing their stock, including dealers and restaurants, and consumers who may be interested in optimizing their purchases. A closely related issue, revaluation is the need to regularly update the value of a stock. This need is especially acute in the growing industry of wine as an investment. In this case, fair-value measurement is compulsory by law. We briefly review methods available to funds and introduce a new quantitative method aimed at achieving compliance with IFRS (International Financial Reporting Standard) 13 for fair valuation. Using auction data on 26,640 lots, we apply this method to compute the current fair value of a basket of 232 different wines. (JEL Classifications: C14, C43, Z11)
‘Chronophilia’: Entries of Erotic Age Preference into Descriptive Psychopathology
Authors: Janssen Diederik F. 
Published: September 2015

A scientific nomenclature oferotic age preferencesinformed the mid- through late nineteenth century joint appearance of homosexuality and sexual abuse of minors on the medico-legal scene. Yet, even in the twenty-first century, legal, psychiatric and culture-critical dimensions of related terms are rarely cleanly distinguished. Review of primary sources shows the ongoing Western suspension of notions of ‘sick desire’, alongside and beyond the medicalisation of homosexuality, between metaphor, legal interdiction and postulated psychopathology. Virtually all early attention to erotic age preference occurred in the context of emergent attention to erotic gender preference. Age of attraction and age difference centrally animate modern homosexuality’s pre-modern past; its earliest psychiatric nomenclature and typologies (1844–69); its early aetiologies stipulating degrees of sexual differentiation (1890s); its concomitant sub-classification (1896–1914); its earliest psychophysiological tests (1950s); and, finally, its post-psychiatric, social scientific typologies (1980s). Several identifications of ‘paedophilia’ were seen throughout the 1890s but as a trope it gained cultural momentum only during, and as a seemingly intriguing corollary of, the progressive depsychiatricisation of homosexuality across the Anglo-European world (late 1950s through 1980s). Early twentieth century sources varied in having it denote (1) a distinct perversion, thus possible ‘complication’ of sexual inversion (2) a discrete corollary of psychosexual differentiation akin to gender preference (3) a distinct subtype of fetishism, thus a likely imprint of early seduction (4) a more intricate expression of erotic symbolism or psychosexual complex or (5) a taste answering to culture, a lack of it, or a libertine disregard for it.
Comparative validity of vitamin C and carotenoids as indicators of fruit and vegetable intake: a systematic review and meta-analysis of randomised controlled trials
Authors: Pennant Mary , Steur Marinka , Moore Carmel , Butterworth Adam , Johnson Laura 
Published: September 2015

AbstractCirculating vitamin C and carotenoids are used as biomarkers of fruit and vegetable intake in research, but their comparative validity has never been meta-analysed. PubMed, EMBASE, CENTRAL, CINAHL and Web of Science were systematically searched up to December 2013 for randomised trials of different amounts of fruit and vegetable provision on changes in blood concentrations of carotenoids or vitamin C. Reporting followed PRISMA guidelines. Evidence quality was assessed using the GRADE system. Random effects meta-analysis combined estimates and meta-regression tested for sub-group differences. In all, nineteen fruit and vegetable trials (n1382) measured at least one biomarker, of which nine (n667) included five common carotenoids and vitamin C. Evidence quality was low and between-trial heterogeneity (I2) ranged from 74 % for vitamin C to 94 % forα-carotene. Groups provided with more fruit and vegetables had increased blood concentrations of vitamin C,α-carotene,β-carotene,β-cryptoxanthin and lutein but not lycopene. However, no clear dose–response effect was observed. Vitamin C showed the largest between-group difference in standardised mean change from the pre-intervention to the post-intervention period (smd0·94; 95 % CI 0·66, 1·22), followed by lutein (smd0·70; 95 % CI 0·37, 1·03) andα-carotene (smd0·63; 95 % CI 0·25, 1·01), but all CI were overlapping, suggesting that none of the biomarkers responded more than the others. Therefore, until further evidence identifies a particular biomarker to be superior, group-level compliance to fruit and vegetable interventions can be indicated equally well by vitamin C or a range of carotenoids. High heterogeneity and a lack of dose–response suggest that individual-level biomarker responses to fruit and vegetables are highly variable.
Soyabean glycinin depresses intestinal growth and function in juvenile Jian carp (Cyprinus carpiovar Jian): protective effects of glutamine
Authors: Jiang Wei-Dan , Hu Kai , Zhang Jin-Xiu , Liu Yang , Jiang Jun , Wu Pei , Zhao Juan , Kuang Sheng-Yao , Tang Ling , Tang Wu-Neng , Zhang Yong-An , Zhou Xiao-Qiu , Feng Lin 
Published: September 2015

AbstractThis study investigated the effects of glycinin on the growth, intestinal oxidative status, tight junction components, cytokines and apoptosis signalling factors of fish. The results showed that an 80 g/kg diet of glycinin exposure for 42 d caused poor growth performance and depressed intestinal growth and function of juvenile Jian carp (Cyprinus carpiovar. Jian). Meanwhile, dietary glycinin exposure induced increases in lipid peroxidation and protein oxidation; it caused reductions in superoxide dismutase (SOD), catalase and glutathione peroxidase (GPx) activities; and it increasedMnSOD, CuZnSOD, GPx1b and GPx4amRNA levels, suggesting an adaptive mechanism against stress in the intestines of fish. However, dietary glycinin exposure decreased both the activity and mRNA levels of nine isoforms of glutathione-S-transferase (GST) (α,μ,π,ρ,θ,κ,mGST1,mGST2andmGST3), indicating toxicity to this enzyme activity and corresponding isoform gene expressions. In addition, glycinin exposure caused partial disruption of intestinal cell–cell tight junction components, disturbances of cytokines and induced apoptosis signalling in the distal intestines>mid intestines>proximal intestines of fish. Glycinin exposure also disturbed the mRNA levels of intestinal-related signalling factorsNrf2,Keap1a,Keap1b, eleven isoforms of protein kinase C and target of rapamycin/4E-BP. Interestingly, glutamine was observed to partially block those negative influences. In conclusion, this study indicates that dietary glycinin exposure causes intestinal oxidative damage and disruption of intestinal physical barriers and functions and reduces fish growth, but glutamine can reverse those negative effects in fish. This study provides some information on the mechanism of glycinin-induced negative effects.
QTIPs: Questionable theoretical and interpretive practices in social psychology
Authors: Brandt Mark J. , Proulx Travis 
Published: September 2015

AbstractOne possible consequence of ideological homogeneity is the misinterpretation of data collected with otherwise solid methods. To help identify these issues outside of politically relevant research, we name and give broad descriptions to three questionable interpretive practices described by Duarte et al. and introduce three additional questionable theoretical practices that also reduce the theoretical power and paradigmatic scope of psychology.
Political orientations do not cancel out, and politics is not about truth
Authors: Pfister Hans-Rüdiger , Böhm Gisela 
Published: September 2015

AbstractDuarte et al. propose that divergent political biases cancel each other out such that increasing political diversity will improve scientific validity. We argue that this idea is misguided. Their recommendations for improving political diversity in academia bear the danger of imposing political interests on science. Scientific scrutiny and criticism are the only viable remedies for bad science.
When theory trumps ideology: Lessons from evolutionary psychology
Authors: Tybur Joshua M. , Navarrete Carlos David 
Published: September 2015

AbstractEvolutionary psychologists are personally liberal, just as social psychologists are. Yet their research has rarely been perceived as liberally biased – if anything, it has been erroneously perceived as motivated by conservative political agendas. Taking a closer look at evolutionary psychologists might offer the broader social psychology community guidance in neutralizing some of the biases Duarte et al. discuss.
Meta-ethical pluralism: A cautionary tale about cohesive moral communities
Authors: Wright Jennifer Cole 
Published: September 2015

AbstractMeta-ethical pluralism gives us additional insight into how moral communities become cohesive and why this can be problematic (even dangerous) – and in this way provides support for the worries raised by the target article. At the same time, it offers several reasons to be concerned about the proposed initiative, the most important of which is that it could seriously backfire.
A conservative's social psychology
Authors: McCauley Clark 
Published: September 2015

AbstractI suggest that social psychologists should stick to studying positive and negative attitudes and give up stigmatizing some attitudes as “prejudice.” I recommend that we avoid assuming that race and ethnicity have no biological foundations, in order to avoid a collision course with modern biology. And I wonder how much difference the target article recommendations can make in the context of hiring a social psychologist for an academic position.