bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical results of definitive radiotherapy for local recurrent kimura disease in the head and neck after surgery: A retrospective study
Authors: Lv Wenlong , Li Shan , Liu Feng , Xue Wangui , Guo Feibao , Hong Jinsheng 
Published: August 2024

AbstractObjectiveTo evaluate the efficacy and safety of definitive radiotherapy in selected patients with local recurrence of Kimura disease of the head and neck after surgery.MethodsThis retrospective study collected the clinical data of 14 patients with postoperative recurrence of Kimura disease of the head and neck who received definitive radiotherapy at the First Affiliated Hospital of Fujian Medical University between 2006 and 2022. The radiation dose ranged from 28 to 40 Gy. Its efficacy and safety were analyzed.ResultsDuring follow‐up, ranging from 17 to 168 months, local control was achieved in 13 (92.9%) of the 14 patients with postoperative recurrence. There were no serious late toxicities except for mild xerostomia in four (28.6%) patients; the patients’ peripheral blood eosinophil count dropped from 1.73×109/L before treatment to 0.42×109/L after treatment, and the eosinophil percentage dropped from 20.64% to 9.78%. Both changes were statistically significant (p<0.001).ConclusionsThe findings of the study suggest that definitive radiotherapy is a viable and effective alternative to repeated surgery for managing recurrent Kimura disease of the head and neck, with significant response rates and a good safety profile. Peripheral blood eosinophil counts and percentages serve as simple and reliable biomarkers for monitoring Kimura disease progression and treatment responses.
Modified Cotton Sorbent for Removing Crude Oil Pollution From Water: Sorption Kinetic Study
Authors: Zibaei Saeed , Tabatabaei Ghomsheh Seyed Mostafa , Mirzaei Masoumeh , Azimi Alireza 
Published: August 2024

ABSTRACTThis research marks an advancement in the field of environmental remediation by introducing a novel sorbent material tailored for the efficient removal of crude oil from industrial wastewater. By focusing on the modification of cotton fibers with charcoal and bentonite, the study addresses the pressing need for sustainable solutions to oil contamination in aquatic environments. Through a comprehensive array of characterization techniques including FT‐IR, TGA, XRD, SEM, EDS, and BET analysis, the structural and surface properties of the modified materials were thoroughly examined, providing insights into their suitability for practical applications. Sorption studies conducted to determine sorption capacity, optimize sorbent amount, and evaluate the effect of contact time on removal efficiency yielded favorable results, highlighting the potential of the developed sorbents to effectively treat crude oil in aqueous solutions. Additionally, the investigation of sorption kinetics using pseudo‐first‐order, pseudo‐second‐order, and intra‐particle diffusion models elucidated the underlying adsorption mechanisms governing the interaction between the sorbent and crude oil molecules. These findings not only contribute to the scientific understanding of sorption processes but also offer practical guidance for the development of optimized sorbent materials and remediation strategies. Overall, this study represents a significant step toward the development of cost‐effective and environmentally friendly methods for oil spill cleanup and industrial wastewater treatment, with implications for sustainable water management practices worldwide. Continued research efforts in this direction hold promise for further advancements in the field, potentially leading to more efficient and scalable solutions for addressing the global challenge of oil contamination in water environments.
Adaptive event‐triggered lateral control for autonomous vehicle system under stochastic‐sampling subject to dynamic quantization
Authors: Jiang Wenke , Luo Mengzhuo , Cheng Jun , Katib Iyad , Shi Kaibo 
Published: August 2024

SummaryIn this paper, we delve into the intricate problem of lateral control in autonomous vehicles, utilizing adaptive event triggering, dynamic quantizers, and incorporating stochastic sampling. By integrating the Adaptive Event‐Triggering Scheme (AETS) and dynamic quantizer in dual channels—namely the sensor‐to‐controller and controller‐to‐observer channels—we aptly cater to the multifaceted road conditions faced by autonomous vehicles. Moreover, in light of Denial of Service (DoS) attacks, our controllers ensure system stability amidst stochastic sampling. While ensuring an effective reduction in the amount of network communication data, the efficiency of the output feedback controllers is also significantly improved, thus enabling the closed‐loop system to be strictly dissipative performance stabilized. To substantiate the efficacy of our proposed method, simulation experiments were rigorously conducted using the Carsim‐Simulink platform, highlighting the enhanced safety of autonomous vehicles in real‐world operations.
Soil chemical properties affecting grain yield and oil content of crambe biofuel crop
Authors: de Marins Araceli Ciotti , Secco Deonir , Ruffato Guilherme Gabriel , Bassegio Doglas , Tiruneh Gizachew Ayalew , Reichert José Miguel 
Published: August 2024

AbstractCrambe (Crambe abyssinica Hochst) is an important grain crop for biodiesel production. The objective of this study was to evaluate how spatial distribution of soil properties affects crambe grain yield and oil content. We analyzed six different sampling densities, with a distance between sampling points ranging from 5.5 to 44 m, to identify correlations among soil and crop variables, and the best spatial distribution. Crambe oil content was not correlated to any of the physicochemical properties, whereas crambe grain yield was correlated with total porosity and exchangeable Al and Ca, effective cation exchange capacity, available P, K, Cu, and Zn, and aluminum and base saturation, with highly significant correlation (p < 0.001) for P and K and Cu and Zn. Most soil properties had spatial dependence degrees from weak to strong, and were modeled by spherical or exponential semi‐variograms. Spatial data showed that low grain yield is associated with high seed oil content, while crambe grain yield was more correlated with phosphorous availability in soil in the first year (2012) and with Ca, Mg, and soil organic matter in the second year (2013). Spatial variability in soil nutrients is attributed to uneven distribution of fertilizers and surface runoff. The results demonstrate sampling density must be increased to generate more accurate maps for soil chemical properties affecting crambe. The use of a grid of 25 points in a 625 m2 of land is suggested, providing more than 60% accuracy for grain yield estimation and more than 40% for most chemical properties’ estimation.
Fruit Peel Derived Carbon Dots for Improved Curcumin Delivery: A Promising Strategy for Enhanced Antimicrobial and Antioxidant Activity
Authors: Patel Pinkesh J. , Gupte Shilpa , Naik Raj , Kailasa Suresh Kumar , Jha Sanjay , Patel Sejal B. , Mehta Vaibhavkumar N. 
Published: August 2024

AbstractCurcumin, known for its proapoptotic, chemo‐preventive, chemo‐therapeutic, antioxidant, anti‐inflammatory, anticancer, and antimicrobial properties, suffers from poor bioavailability, limiting its applications. This study aims to enhance curcumin's bioavailability using carbon dots (CDs) synthesized from fruit peels as a novel nano formulation. CDs were synthesized via hydrothermal synthesis using banana and orange peels as carbon sources, and functionalized with curcumin to improve its solubility and cellular uptake. The synthesis and functionalization of CDs were confirmed using Fluorescence spectrophotometer, FT‐IR, and HR‐TEM. The curcumin‐loaded CDs exhibited superior antimicrobial activity, with minimum inhibitory concentrations of 22 μg/mL for Staphylococcus aureus (S. aureus), 11 μg/mL for Bacillus subtilis (B. subtilis), and 22 μg/mL for Bacillus cereus (B. cereus). Additionally, the developed CDs demonstrated enhanced antioxidant activity compared to curcumin in DMSO. The findings indicate that curcumin‐loaded CDs significantly increase the biological activity of curcumin, offering a promising approach for its incorporation into functional foods, beverages, and pharmaceutical products. This study highlights the novel use of CDs to overcome the bioavailability issues of water‐insoluble bioactive compounds like curcumin, presenting a significant advancement in nano‐formulation technology.
Preparation of Light‐Diffusing Materials Combined with High Transmittance and High Haze–Comparing the Effectiveness of Diameter and Refractive Index
Authors: Ouyang Xing , Lei Shuai , Tang Xiao , Chen Dazhu 
Published: August 2024

AbstractPreparing light‐diffusing material (LDM) combined with high haze and high transmittance has a significant value, but it is a challenge for the industry. The refractive index and diameter of light‐diffusing particles are the main factors. Two series of silicone microspheres with different diameters and refractive indices were prepared through precipitation polymerization and applied in LDM. The morphology of particles and LDM were investigated by scanning electron microscope. The corresponding thermal stability was studied by a thermal gravimetric analyzer. Furthermore, the influence of diameter and refractive index on light‐diffusing properties was explored systematically. The results show that the silicone particles have excellent thermal stability and can disperse evenly in a polycarbonate matrix. The corresponding LDM also has good thermal stability. It is the diameter, not the refractive index, acting as the key factor in preparing LDM combined with high haze and high transmittance. When achieving the same haze, selecting an appropriate diameter can prepare LDM with higher transmittance than other diameters. Different refractive indices lead to similar transmittance and haze of LDMs, but the refractive index can markedly affect the loading of particles to achieve an expected light‐diffusing property. This research has aspiring guidance for the industry.
9‐Fluorenone Catalyzed Visible Light Oxidation of Hydrazides: An Efficient Route for the Synthesis of N,N′‐Diacylhydrazines Derivatives
Authors: Khobrekar Pritesh P. , Chari Vishnu R. , Bugde Sandesh T. 
Published: August 2024

AbstractA visible light‐mediated oxidative coupling of hydrazides into corresponding N,N’‐ diacylhydrazines using a commercially available and low‐cost metal‐free photocatalyst was reported. The versatility of the reaction has been demonstrated across a broad spectrum of functional groups present in hydrazides. Interestingly, the developed methodology was utilized to synthesize symmetrical and unsymmetrical N,N’‐diacylhydrazines in moderate yields. Density Functional Theory (DFT) calculations, along with control reactions and quenching studies, provide evidence supporting the proposed mechanism, favoring the photoredox pathway. Additionally, NMR and UV‐Vis studies confirmed the generation of H2O2 in the reaction mixture, which strengthens the proposed mechanism. To our knowledge, this is the first report for the conversion of hydrazides to N,N’‐diacylhydrazines using 9‐fluorenone as an organic photoredox catalyst.
Unveiling the Therapeutic Potential of Quinazolinone Derivatives in Cancer Treatment: A Comprehensive Exploration
Authors: Kaur Jasneet , Kaur Sukhmeet , Muskan  , Kaur Navneet , Kumar Vipan , Anand Amit 
Published: August 2024

AbstractQuinazolinone derivatives have garnered attention for their diverse biological activities, including anticancer properties. This review combines findings from 2018 to 2024, focusing on the impact of quinazolinones on cancer cells, tubulin formation, and EGFR/PI3 K pathways. By unraveling the intricacies of structure‐activity relationships, this review endeavors to provide guidance for researchers in identifying promising avenues for the development of cancer treatments. Although in vitro studies underscore significant potential, it is imperative that future research prioritizes pre‐clinical investigations to seamlessly traverse the transitional phase towards clinical applications, thereby propelling the advancement of quinazolinone‐based cancer therapy.
Atomic Layer Deposition of γ‐Al2O3 on Hexagonal Boron Nitride: A Hybrid Support for Metallocene Catalysts
Authors: Mazhar Hassam , Shehzad Farrukh , Al‐harthi Mamdouh A. 
Published: August 2024

AbstractHexagonal boron nitride (hBN), also known as white graphene, has recently gained larger attention due to its unique physical and chemical properties. Owing to its excellent thermal conductivity and stability, hBN has been reported as an effective filler in many polymers. This study explores the potential of hBN as a catalyst support and filler for olefin polymerization. We report the atomic layer deposition (ALD) of γ‐Al2O3 on hydroxyl‐functionalized hBN. The alumina precursor, methylaluminoxane, showed high selectivity, depositing Al species only on the B‐OH sites, while B−O‐O−B sites remained unreacted. The hBN/γ‐Al2O3 hybrid was characterized by Fourier transform infrared (FTIR) spectroscopy, X‐Ray diffraction and transmission electron microscopy (TEM). The deposition of the aluminum over the hBN sheets was confirmed. The hBN/γ‐Al2O3 was used as a support for metallocene catalysts. The supported catalyst complex was highly active and produced ethylene‐propylene polymers with molecular weights up to 10 times higher, as demonstrated by gel permeation chromatography (GPC)
Boosting the Sodium‐Ion Storage Performance of Prussian Blue Analogs by Crystalline Regulation
Authors: Qie Liangliang , Chen Yiming , Wu Guiling , Zhang Xiaowen , Yu Jiage , Pi Yuqiang , Ding Yu , Wang Feng 
Published: August 2024

AbstractIn the development of practical sodium‐ion batteries, electrochemical performance and cost efficiency of the electrode materials are vital considerations. Prussian blue analogs (PBAs) have emerged as promising cathode materials due to their affordability, high theoretical capacity, and cycling stability. However, low crystallinity can negatively impact their performance. This study introduces a straightforward “chelating agent‐assisted” method for producing highly crystalline PBAs. The resulting cathode boasts excellent characteristics, including a high capacity of 150 mAh g−1, an initial Coulombic efficiency of 87.2 %, a long cycling lifespan of 1000 cycles, and superior rate performance. Furthermore, the study shows that the low structure distortion and high sodium diffusion coefficient can be attributed to the suppression of structural defects, as evidenced by in situ synchrotron powder diffraction. We believe these findings have the potential to enable the widespread use of PBAs in sodium‐ion batteries for an affordable and large‐scale energy storage system.
Synthesis, Conformational Properties and DFT Computational Studies of [3]Metacyclo[3](1,3)pyrenophanes
Authors: Islam Md. Monarul , Sharma Bigyan , Wang Chuan‐Zeng , Rahman Shofiur , Alodhayb Abdullah N. , Georghiou Paris E. , Elsegood Mark R. J. , Yamato Takehiko 
Published: August 2024

AbstractTwo new 6,17‐di‐tert‐butyl‐[3]metacyclo[3](1,3)‐pyrenophane‐2,11‐diones 8 a–b were synthesized by the coupling reaction of 1,3‐bis(bromomethyl)‐7‐tert‐butylpyrene 5 with the corresponding TosMIC‐adducts 7 a–b in CH2Cl2 and water under phase‐transfer conditions, followed by acid treatment. Wolff–Kishner reduction of 8 a–b afforded in good yields the corresponding 6,17‐di‐tert‐butyl‐[3]metacyclo[3](1,3)‐pyrenophanes 9 a–b. The spectroscopic data of both 8 a and 8 b show that they adopt anti‐conformations. In contrast, both pyrenophanes 9 a and 9 b adopt syn‐conformations. Variable‐temperature 1H NMR studies were carried out to determine the conformational behavior of the pyrenophanes. A single crystal X‐ray structure of 8 a shows that it also has an anti‐conformation in the solid state. Density functional theory (DFT) computations of 8 a–b and 9 a–b were used to determine their energy‐minimized structures and the total energies of their different conformers.
Enhanced Photocatalytic Degradation of Methyl Orange by Metal‐Tio2 Nanoparticles
Authors: Zhang Wei , Jiang Tuohong , Li Ning , Zhao Shiling , Zhao Yu 
Published: August 2024

AbstractIn this study, a series of transition metal‐doped TiO2 was prepared by a simple sol‐solvothermal method. Mix an ethanol solution of tetrabutyl titanate and metal nitrate solution to obtain a homogeneous sol, which is then subjected to solvothermal treatment. After calcination, the metal‐TiO2 naoncomposite was obtained. Selected transition metal precursors, including Cu, Fe, Ag, Cr, Co and Zn, were doped into TiO2 nanocatalysts to assess photocatalytic degradation activities. The results show that 1 mol % Ag−TiO2 photocatalyst has a larger specific surface area, a stable anatase phase and the narrowest forbidden band energy (3.00 eV). In photocatalytic degradation of methyl orange (MO) tests, 1 mol % Ag−TiO2 could reach 100 % decolourisation after 70 min and 75.43 % mineralisation after 90 min. ESR analysis confirmed that Ag doping significantly increased the content of ⋅O2− and ⋅OH for the TiO2 catalyst, which are responsible for the oxidation reactions and consequently degradation of pollutants. The photocatalytic degradation mechanism of MO was also proposed. The TOC analyses confirmed the mineralization of MO. The excellent thermal and chemical stability of 1 mol % Ag−TiO2 has also been demonstrated by thermogravimetric analysis and cycling experiments. Electrochemical tests have also demonstrated the excellent electrochemical properties of 1 mol % Ag−TiO2.
Lipid‐Coated Mesoporous Silica Nanoparticles for pH‐Responsive Release and Enhanced Anti‐Proliferative Activity of Piperlongumine Natural Product
Authors: Ishaniya Wickneswaran , Sugantharam Karnan , Subramani Muthuraman , Kumar Arumugam Madan , Gopinath Pushparathinam , Rajendran Saravanakumar , Ganeshpandian Mani 
Published: August 2024

AbstractThe incorporation of natural products into a suitable delivery system has the potential to augment their therapeutic effectiveness significantly. In this study, we demonstrate how silicasomes, a lipid‐coated mesoporous silica nanorods, influence the anticancer potency and release behaviour of the natural product. Piperlongumine (Pip), a natural product isolated from long pepper, is loaded into mesoporous silica nanorods (MSNRs) followed by a bilayer coating made of 1,2‐Dimyristoyl‐sn‐glycero‐3‐phosphocholine (DMPC). The size and morphology of Pip‐loaded MSNRs (Pip@MSNRs) and phospholipid‐coated Pip@MSNRs (PL‐Pip@MSNRs) are characterized well using suitable analytical techniques. The release of Pip from Pip@MSNRs attained saturation at 48 h while PL‐Pip@MSNRs exhibited the same only after 100 h in both simulated physiological and endolysosomal acidic environments. Moreover, PL‐Pip@MSNRs displayed a higher percentage of Pip release in an acidic medium than in a physiological medium after 24 h. These results confirm that the DMPC coating could assist the pH‐responsive and sustained release of loaded drug from silica nanorods. Most importantly, PL‐Pip@MSNRs demonstrate a higher potency of cytotoxicity and apoptosis against MCF‐7 (Human Breast Carcinoma) cells than the Pip@MSNRs, emphasizing the significance of DMPC‐coated MSNRs as a suitable nanocarrier for natural product delivery.
Oxide Derivatives of Nb2CTx MXene and Their Application as Electron Transport Layers in Perovskite Solar Cells: Unraveling the Oxidation Process and Functionalization
Authors: Yang Lin , Liu Ziyan , Zheng Tianfang , Li Peng , Ma Jiangang , Zhang Xintong , Zhu Hancheng , Wang Xiao‐Feng , Liu Yichun 
Published: August 2024

AbstractIn the realm of photovoltaic research, 2D transition metal carbides (MXenes) have gained significant interest due to their exceptional photoelectric capabilities. However, the instability of MXenes due to oxidation has a direct impact on their practical applications. In this work, the oxidation process of Nb2CTx MXene in aqueous systems is methodically simulated at the atomic level and nanosecond timescales, which elucidates the structural variations influenced by the synergistic effects of water and dissolved oxygen, predicting a transition from metal to semiconductor with 44% C atoms replaced by O atoms in Nb2CTx. Moreover, Nb2CTx with varying oxidation degrees is utilized as electron transport layers (ETLs) in perovskite solar cells (PSCs). Favorable energy level alignments with superior electron transfer capability are achieved by controlled oxidation. By further exploring the composites of Nb2CTx to its derivatives, the strong interaction of the nano‐composites is demonstrated to be more effective for electron transport, thus the corresponding PSC achieves a better performance with long‐term stability compared with the widely used ETLs like SnO2. This work unravels the oxidation dynamics of Nb2CTx and provides a promising approach to designing ETL by exploiting MXenes to their derivatives for photovoltaic technologies.
Temperature‐Sensitive Polymer‐Driven Nanomotors for Enhanced Tumor Penetration and Photothermal Therapy
Authors: Ma Beng , Yu Ying , Li Jiayi , Zhang Yunqi , Sun Bo , Ji Anqi , Song Kexing , Shi Linlin , Hu Hao , Gao Shegan , Cheng Haoyan 
Published: August 2024

AbstractSelf‐propelled nanomotors possess strong propulsion and penetration abilities, which can increase the efficiency of cellular uptake of nanoparticles and enhance their cytotoxicity against tumor cells, opening a new path for treating major diseases. In this study, the concept of driving nanomotors by alternately stretching and contracting a temperature‐sensitive polymer (TS‐P) chain is proposed. The TS‐Ps are successfully linked to one side of Cu2‐xSe@Au (CS@Au) nanoparticles to form a Janus structure, which is designated as Cu2‐xSe@Au‐polymer (CS@Au‐P) nanomotors. Under near‐infrared (NIR) light irradiation, Cu2‐xSe nanoparticles generate photothermal effects that change the system temperature, triggering the alternation of the TS‐P structure to generate a mechanical force that propels the motion of CS@Au‐P nanomotors. The nanomotor significantly improved the cellular uptake of nanoparticles and enhanced their penetration and accumulation in tumor. Furthermore, the exceptional photothermal conversion efficiency of CS@Au‐P nanomotors suggests their potential as nanomaterials for photothermal therapy (PTT). The prepared material exhibited good biocompatibility and anti‐tumor effects both in vivo and in vitro, providing new research insights into the design and application of nanomotors in tumor therapy.