bluuebunny/crossref_metadata_2025_split huggingface dataset:
Intricate diagnosis due to falsely elevated testosterone levels by immunoassay
Authors: Gardini Benedetta , Bondanelli Marta , Cariani Alessio , Zatelli Maria Chiara , Ambrosio Maria Rosaria 
Published: February 2025

Abstract

Purpose
Hormone immunoassay may be subject to interferences and, although rarely reported, this can occur for testosterone too. This work is aimed to highlight the importance of considering possible analytical interferences when the biochemical data doesn’t match with the clinical picture.

Methods
We report three cases of insidious diagnosis due to laboratory interference in testosterone immunoassay, and we provide a brief literature review on this issue.

Results
We found falsely high testosterone levels due to the presence of heterophilic antibodies, leading to unnecessary investigations, misdiagnosis and inappropriate treatments.

Conclusion
The detection of elevated testosterone levels on immunoassay not corresponding to clinical findings need to be confirmed by liquid chromatography-tandem mass spectroscopy, prior to escalation of complex diagnostic investigation and care.
Patchy Internalization: Transnational Migration and Local Buildings in the Bosnian Borderland
Authors: Hromadžić Azra 
Published: February 2025

Abstract
This article explores transnational migration to the European Union (EU) and its entanglements with human-built structures in Bihać, a city in northwestern Bosnia and Herzegovina. In March 2018, this postwar and postsocialist city located on the northwestern edge of the country emerged as the newest “hot spot” on the so-called Balkan migrant route. This is due to the city’s proximity to Croatia, and thus the EU border, and because of the closing of the borders and routes elsewhere in Europe. Since 2018, the city has been harboring up to 5000 refugees and migrants from South Asia, the Middle East, and Northern Africa who are repeatedly trying to cross into Croatia and the rest of the EU. While waiting to cross into the EU, migrants navigate everyday living among the people of Bihać. In this article, I illustrate how buildings in Bihać facilitate migrants’ experiences of dislocation and migration. By focusing on one, seemingly irrelevant (to transnational migration) structure in town—the Center—I pay attention to the less noticeable spaces in town. It is precisely in these less conspicuous buildings, I contend, that migrant encounters occur and get incorporated into the local environment in a patchy fashion—folding into some spaces while skipping over others. I call this incorporation of transnational migration and violent border regimes into local built environments “patchy internalization.”
The current landscape of mental health challenges in women with PCOS: a narrative review
Authors: Khan Faathimah , Govender Nalini , Thandar Yasmeen 
Published: February 2025

Abstract
Polycystic ovary syndrome (PCOS) research is dominated by the clinical perspective, whilst the psychological experiences of women with PCOS remain less understood. This narrative review explores mental health challenges of women with PCOS, encompassing common psychiatric disorders, emotional challenges, and psychosocial challenges. An online search of published literature was conducted via PubMed and Google Scholar using the terms “polycystic ovary syndrome”, “mental health”, “psychological”, “emotional” and “psychosocial”. Only articles that were directly applicable to mental health, emotional and psychosocial challenges were reviewed. Women with PCOS face increased risks of anxiety, depression, and eating disorders, alongside emotional burdens such as stress and social isolation, which stem from the syndrome’s symptoms and societal stigma. Psychosocial challenges, including body image dissatisfaction and social functioning difficulties, further exacerbate these issues. These findings underscore the necessity for comprehensive PCOS management that includes regular mental health screenings and addresses the complex interplay of psychological factors, emphasizing the importance of further research to deepen understanding and improve care strategies.
Long noncoding RNA SNHG4 promotes glioma progression via regulating miR-367-3p/MYO1B axis in zebrafish xenografts
Authors: Zhang Yueqing , Wang Yongjin , Yang Yang , Sun Chunming 
Published: February 2025

Abstract
Glioma is one of the most malignancy and prevalent tumor in the human central nervous system, which is associated with severe morbidity and high mortality. Numerous studies have explained the clear correlation between abnormal expression of lncRNA and progression of Glioma. LncRNA small nucleolar RNA host gene 4 (SNHG4) have been proved to play oncogenesis roles in various tumors, however, the underlying mechanism remains to be explored deeply. In this study, by analysis of the public database, we found that SNHG4 was upregulated in multiple cancer tissues, including glioma. Subsequently, the functional roles of SNHG4 were investigated, and we found that knockdown of SNHG4 remarkedly inhibited cell proliferation, migration. While, overexpression of SNHG4 enhanced these functions of glioma cells in vitro. Meanwhile, as the in vivo tool, zebrafish xenograft model was used to verify the functions of SNHG4 in glioma cells. Mechanically, we identified that SNHG4 or MYO1B could bind with miR-367-3p by the luciferase reporter assays. Furthermore, the rescue experiments showed that the inhibition of miR-367-3p or the expression of MYO1B partially rescue the inhibition effects of SNHG4 in glioma cells. Our study reveals that SNHG4 promotes the proliferation, migration of glioma via regulating miR-367-3p/MYO1B axis.
Monoclinic Angle of the B19′ Phase in a Cold Worked NiTi
Authors: Li Yingchao , Bakhtiari Sam , Xu Dawn , Yang Hong , Liu Yinong 
Published: February 2025

Abstract
This study evaluated the monoclinic angle of the B19′ martensite in a cold worked equiatomic Ni50Ti50 alloy by means of transmission electron microscopy (TEM) analysis. It also presents a minimum error approach to determining the small changes to the monoclinic angle based on Fast Fourier Transformation patterns generated from high resolution TEM micrographs. The monoclinic angle of the B19′ martensite was found to reduce from 97.3° in the annealed state to 93.8° after 24.4% cold deformation by wire drawing. Such finding may help to interpret some common experimental observations such as the reduction of transformation strains in cold worked NiTi shape memory alloys or in alloys after thermal transformation cycling.
Health-Related Experiences as a Motivation for Pursuing Health Professional Education
Authors: Osborne Emma , Anderson Vivienne , Robson Bridget 
Published: February 2025

Abstract
Health professional students may experience overlaps between their own lives and their course of study. Such experiences may include: personal experiences of illness or disability; family illness, caregiving or bereavement; and collective experiences of health inequities. However, little is known about the role of such experiences in students’ decisions to study health. We describe findings from interviews with 22 students and graduates in Aotearoa New Zealand, who self-identified as having experienced significant overlaps between their study and own lives. Participants described studying health in response to health-related experiences in four ways: meeting family needs; improving life for others in similar situations; exposure to healthcare as consolidating interests; and making meaning after bereavement. We also explore contexts in which participants made decisions about study, including family support, secondary school, and early tertiary study. We argue that health-related experiences and commitment to whānau| family should be recognised more widely in exploring why and how students select health professional qualifications. We also identify the importance of academic and career mentoring programmes throughout secondary and early tertiary education which nurtured students’ aspirations for success in sciences and health education.
Streamlining Legal Document Management: A Knowledge-Driven Service Platform
Authors: Bellandi Valerio , Castano Silvana , Montanelli Stefano , Siccardi Stefano 
Published: February 2025

Abstract
Managing legal documents, particularly court judgments, can pose a significant challenge due to the extensive and continuously growing volume of involved data. The IDJ platform proposed in this paper aims to tackle this challenge by providing knowledge-driven services designed to enforce the streamlined management of legal documents. The IDJ platform consists of a set of modules, repositories, and data flows that interoperate to realize service pipelines enforcing legal document analytics and exploration processes based on a combination of Natural Language Processing (NLP), machine learning, and syntactic rules. In the paper, we describe two service pipelines enforcing knowledge-driven processes over legal documents, namely the entity-based document analytics, and the concept-based document exploration. A comprehensive experimentation of the proposed knowledge-based service pipelines in a real scenario is finally provided, by considering a corpus repository of Italian court decisions collected in the framework of the Next Generation UPP (NGUPP) digital justice project.
Association between COVID-19 history and postoperative delirium in elderly patient undergoing elective surgery: a prospective, two-center observational cohort study
Authors: Duan Wen , Yang Jin-Jin , Fang Pan-Pan , Zhu Wen-Jie , Zhang Yue , Li Xin-Yu , Ma Da-Qing , Shan Yang-Yang , Liu Xue-Sheng , Yang Jian-Jun 
Published: February 2025

Abstract

Purpose
An increased incidence of delirium was reported in patients especially in elderly patient during the acute phase of coronavirus disease 2019 (COVID-19). However, whether COVID-19 history increases the risk of postoperative delirium (POD) in elderly patients remains unclear. This study aims to investigate the association between COVID-19 history and POD in elderly patients undergoing elective surgeries.

Methods
In this prospective, two center cohort study, 500 elderly patients undergoing elective surgeries from March to May 2023 were analyzed. The primary exposure was a history of COVID-19. The primary outcome was POD assessed with 3-min diagnostic confusion assessment method or confusion assessment method for the intensive care unit within three days after surgery. We used inverse probability of treatment weighting (IPTW) to balance the differences between patients with or without a history of COVID-19. The association between COVID-19 history and POD was estimated using a logistic regression model with IPTW. Additionally, we next exploringly conducted subgroup analysis and assessed interaction effects to evaluate the impact of COVID-19 history on POD based on frailty/pre-frailty, cancer, surgical type/classification, sex, profession, and residence type.

Results
In this cohort, 412 patients had a history of COVID-19 with an incidence 16% of POD while 88 were uninfected with 15.9% of POD incidence. There was no association between COVID-19 history and POD [adjusted odds ratio (ORadj) 1.20 (0.80–1.79), P = 0.378] in elderly patients undergoing elective surgery. However, POD was significantly increased in patients with COVID-19 history who were pre-frailty/frailty or with cancers [ORadj 2.41 (1.19–5.10) and ORadj 2.29 (1.23–4.39), respectively].

Conclusion
This preliminary exploratory study found no association between a history of COVID-19 and POD in elderly patients undergoing elective surgery.

Trial registration
Registered at the Chinese Clinical Trial Center (https://www.chictr.org.cn/showproj.html?proj=192846) with No. ChiCTR2300069308 on Mar 13, 2023.
Provision of Practicum in Australian Postgraduate Courses Preparing Special/Inclusive Educators
Authors: Stephenson Jennifer , Ganguly Rahul , Kemp Coral , Sarandrea Anne Marie , Salisbury Catherine 
Published: February 2025

Abstract
The importance of professional experience is clearly recognised in initial teacher education and in other professions. In this study, we explore one element of professional experience for trainee special/inclusive educators, placement in an educational setting for practicum, and how it is provided in postgraduate Australian special/inclusive education courses. We extracted data from publicly available material for all Australian postgraduate courses designed to prepare special and/or inclusive educators. Available data included the length of practicum, content of the unit related to practicum, supervision and placement arrangements, and assessment. We found that only 59% of courses included a unit that required completion of a practicum placement. Given there are no mandatory standards for special/inclusive educators, there was considerable variation in the way practical skills were assessed, the content of practicum units, mentoring arrangements and personnel involved. Practicum placements ranged from 10 to 30 days, and only two courses provided more than one placement. Further research is needed to consider the broader range of professional experiences that may be embedded in courses. We suggest that longer practicum placements should be mandatory in special/inclusive educator professional preparation and should include assessment of the implementation of specific evidence-based practices including collaboration with others.
Red meets brown: investigating the antiliberal political convergence of Italy’s extremes
Authors: Guerra Nicola 
Published: February 2025

Abstract
This study examines the political communication strategies of the Italian Marxist-Leninist and neo-Stalinist party, Sovereign and Popular Democracy (DSP), through a qualitative thematic analysis of its online discourse. The analysis identifies the core elements of the party’s agenda and assesses their potential alignment with the red-brownist movement, often linked to the pro-Russian far right. The research investigates the historical and political intersections between the Stalinist communist sphere and the postfascist Eurasianist and red-brownist factions. Particular attention is given to their shared anti-Western stance and historical connections to ‘left-wing fascism’ in the post-Second World War era. Italy provides a crucial case study, given its postwar role as a hub for radical movements on both the left and the right. The analysis also considers the ideological trajectory of the Italian far-right, particularly the Jeune Europe movement, to situate DSP’s discourse within broader historical and ideological frameworks.
Impact of Breakfast Consumption Timing versus Breakfast Omission on Post-Lunch Glycaemia and Insulinaemia in Adolescent Girls: A Randomised Crossover Trial
Authors: Afeef Sahar , Zakrzewski-Fruer Julia K. , Thackray Alice E. , Barrett Laura A. , Tolfrey Keith 
Published: February 2025

Abstract
Adolescent girls often skip breakfast due to time constraints and reduced morning appetite. This study examined the acute impact of breakfast consumption timing versus breakfast omission (BO) on glycaemic and insulinaemic responses to lunch in infrequent breakfast-consuming girls. Fifteen girls (13.1±0.8 years) completed three conditions in a randomised crossover design: early-morning breakfast consumption (EM-BC; 8:30), mid-morning breakfast consumption (MM-BC; 10:30), and BO. A standardised lunch was provided at 12:30, followed by a 2-h post-lunch observation period. Blood and expired gas samples were collected periodically. Linear mixed models with Cohen’s d effect sizes compared outcomes between conditions. Pre-lunch glucose and insulin incremental area under the curve (iAUC) were higher in the breakfast conditions versus BO (P≤0.009), with no differences between breakfast conditions. MM-BC reduced post-lunch glucose iAUC by 36% and 25% compared with BO and EM-BC, respectively (P<0.001, d=0.92–1.44). A moderate, non-significant 15% reduction in post-lunch glucose iAUC was seen with EM-BC versus BO (P=0.077, d=0.52). These reductions occurred without changes in post-lunch insulinemia (P≥0.323) and were accompanied by increased post-lunch carbohydrate oxidation compared with BO (P≤0.018, d=0.58–0.75); with no differences between EM-BC and MM-BC. MM-BC lowered glycaemic response over the experimental period compared with BO (P=0.033, d=0.98) and EM-BC (P=0.123, d=0.93), with no difference between EM-BC and BO. Compared with BO, both breakfast conditions lowered post-lunch glycaemic responses with mid-morning breakfast eliciting a greater second-meal effect than early-morning breakfast. These findings indicate the breakfast-to-lunch meal interval may be a crucial factor affecting postprandial glycaemia in infrequent breakfast-consuming girls.
School Food and Nutrition Environments in the Pacific Islands: Opportunities to support healthier diets
Authors: Burkhart Sarah , Singh Pragya , Hunter Danny , Raneri Jessica E. 
Published: February 2025

Abstract
The Pacific Islands region is home to a diversity of countries and territories, who are at the forefront of climate change and the triple burden of malnutrition. In recent years there has been increasing interest in schools as a setting for transforming food systems, improving nutrition and health outcomes, increasing educational outcomes and enhancing livelihoods in the Pacific Islands. This review examines and describes current school food and nutrition initiatives within the literature that aim to promote healthier, sustainable diets within the Pacific Islands region. As there is a paucity of literature in this area of interest in the Pacific Islands, the review focuses on the policy landscape, the provision of food near, and in schools, nutrition education, and future opportunities. The available literature demonstrates that there is broad regional interest and momentum from numerous stakeholders to enhance SFNE in the Pacific Islands, with several opportunities for future activities. While there are frameworks to explore food environments available there is a need for a Pacific Islands school food environment conceptual framework that captures aspects, both within and around schools, that can guide research and assessment for robust comparable data collection. This may in turn support healthier SFNE and ultimately nutritious food choices for children and adolescents
The Cold War as a label, meaning, and referent
Authors: Mahoney James 
Published: February 2025

Abstract
In this article, I discuss the Cold War as a label, meaning, and referent in academic research. I consider how the label “the Cold War” focuses attention on the conflict between the United States and USSR and draws attention away from the Global South. I show how academics often use the category the Cold War as a diminished subtype of interstate war, with the adjective cold calling attention to the absence of direct military combat. I analyze the meanings and referents associated with different ways of “casing” the Cold War: a case of cold war, a case of interstate rivalry, and a case of empire building. I also examine the separate meanings of the Cold War when it is treated as a world-historical time versus an event. Using the essays in this special issue, I examine how sociologists study the Cold War as an empirical referent. I find that the cultural orientation of sociology emphasizes symbolic and performative aspects of the Cold War that are not traditionally emphasized in work on the Cold War.
Gestational Diabetes Mellitus and the Longitudinal Fetal Growth Trajectories in Twin Pregnancies
Authors: Shu Xinyu , Yao Mi , Li Chenglong , Chen Na , Zhang Yan , Kang Xin , Juan Juan , Yang Huixia 
Published: February 2025

Abstract
Although it is well established that gestational diabetes mellitus (GDM) is associated with fetal overgrowth in singleton pregnancies, little is known about its role in twins. We aimed to explore the relationship between GDM and the longitudinal fetal growth in twin pregnancies. This was a retrospective matched cohort study of GDM and non-GDM twin pregnancies delivered ≥36 weeks without other complications. All the women performed ≥3 ultrasounds after 22 weeks. Linear mixed models (LMMs) were used to explore the relationships between longitudinal fetal growth trajectories and GDM. Group-based trajectory modeling (GBTM) and generalized estimating equation (GEE) were applied to identify the latent growth patterns and investigate their relationships with GDM. In total, 215 GDM and 645 non-GDM twins were included, the majority of the patients did not require medication therapy (n = 202, GDMA1). LMM revealed that, compared with non-GDM, GDM was associated with an average increase in fetal weight of 4.36 g (95% CI [1.25, 7.48]) per week. GBTM and GEE further revealed that GDM increased the odds of fetal weight trajectory to nearly 40% of the total fetal weight trajectory, classified into the high-speed group (aOR = 1.39, 95% CI [1.03, 1.88]), associating with a 49.44 g (95% CI [11.41, 87.48]) increase in birth weight. Subgroup analysis revealed that all these differences were only significant among the GDMA1 pregnancies (p < .05). GDM (GDMA1) is significantly associated with an increase in fetal weight during gestation in twin pregnancies. However, this acceleration is mild, and its significance requires further exploration.
An Integrated Global‐To‐Regional Scale Workflow for Simulating Climate Change Impacts on Marine Ecosystems
Authors: Ortega‐Cisneros Kelly , Fierros‐Arcos Denisse , Lindmark Max , Novaglio Camilla , Woodworth‐Jefcoats Phoebe , Eddy Tyler D. , Coll Marta , Fulton Elizabeth , Oliveros‐Ramos Ricardo , Reum Jonathan , Shin Yunne‐Jai , Bulman Cathy , Capitani Leonardo , Datta Samik , Murphy Kieran , Rogers Alice , Shannon Lynne , Whitehouse George A. , Adekoya Ezekiel , Dias Beatriz S. , Fuster‐Alonso Alba , Hansen Cecilie , Husson Bérengère , McGregor Vidette , Morell Alaia , Morzaria Luna Hem‐Nalini , Ouled‐Cheikh Jazel , Ruzicka James , Steenbeek Jeroen , Stollberg Ilaria , Subramaniam Roshni C. , Tulloch Vivitskaia , Bryndum‐Buchholz Andrea , Harrison Cheryl S. , Heneghan Ryan , Maury Olivier , Pozo Buil Mercedes , Schewe Jacob , Tittensor Derek P. , Townsend Howard , Blanchard Julia L. 
Published: February 2025

AbstractAs the urgency to evaluate the impacts of climate change on marine ecosystems increases, there is a need to develop robust projections and improve the uptake of ecosystem model outputs in policy and planning. Standardizing input and output data is a crucial step in evaluating and communicating results, but can be challenging when using models with diverse structures, assumptions, and outputs that address region‐specific issues. We developed an implementation framework and workflow to standardize the climate and fishing forcings used by regional models contributing to the Fisheries and Marine Ecosystem Model Intercomparison Project (FishMIP) and to facilitate comparative analyses across models and a wide range of regions, in line with the FishMIP 3a protocol. We applied our workflow to three case study areas‐models: the Baltic Sea Mizer, Hawai'i‐based Longline fisheries therMizer, and the southern Benguela ecosystem Atlantis marine ecosystem models. We then selected the most challenging steps of the workflow and illustrated their implementation in different model types and regions. Our workflow is adaptable across a wide range of regional models, from non‐spatially explicit to spatially explicit and fully‐depth resolved models and models that include one or several fishing fleets. This workflow will facilitate the development of regional marine ecosystem model ensembles and enhance future research on marine ecosystem model development and applications, model evaluation and benchmarking, and global‐to‐regional model comparisons.