bluuebunny/crossref_metadata_2025_split huggingface dataset:
L'économie de la passion
Authors: Slimani Hassen 
Published: February 2015

Cet article repose sur une enquête ethnographique réalisée en 2002 qui porte sur la formation et l’insertion professionnelle des diplômé(e)s du brevet d’État d’éducateur sportif en activités équestres, rénové en 2003 en brevet professionnel. Son propos vise à démontrer que la survie des moniteurs(trices) sur les marchés du travail de l’enseignement et de l’animation tient autant sinon plus à la détention ou non de capital scolaire et compétitif, et surtout social et affectif, qu’aux compétences et certifications acquises. Ainsi, à diplôme égal, le positionnement sur le marché matrimonial et/ou l’héritage familial (économique, social et patrimonial) facilitent une insertion professionnelle durable. Et, dans ces professions sur-féminisées où prédomine un fort taux de turn-over , les femmes, plus nombreuses et plus jeunes, constituent sui generis les plus fortes cohortes à s’engager dans les pratiques équestres et, par passion, en formation. Leur éviction pour « incompétence » est alors vécue comme plus légitime que pour leurs homologues masculins.
Les classes populaires face à l'impératif scolaire
Authors: Cayouette-Remblière Joanie 
Published: February 2015

Cet article interroge les raisons de la persistance des orientations socialement différenciées après la seconde « explosion scolaire ». S’appuyant sur la reconstitution des trajectoires scolaires de deux cohortes entières d’élèves ainsi que sur une enquête ethnographique, il met en évidence une contradiction latente aux discours des agents scolaires : d’un côté, ils intègrent et agissent en fonction de la hiérarchie entre enseignement GT et voie professionnelle ; de l’autre, ils nient et disent regretter cette hiérarchie. L’article questionne ensuite les modalités de transmission de cette hiérarchie niée aux élèves. De ce fait, il contextualise la façon dont les « vœux » scolaires sont produits, en dégageant quatre principes d’orientation : l’orientation « anormale » des élèves des classes moyennes et supérieures, l’orientation vécue comme « irréaliste » des garçons des franges supérieures des classes populaires, l’orientation « généreuse » de certaines filles de classes populaires et l’orientation par exclusion et auto-exclusion des franges les plus démunies des classes populaires.
Les comportements déviants des consommateurs vus par leurs pairs : le cas du commerce de détail
Authors: Perron Frédérique , Djelassi Souad 
Published: February 2015

Les comportements déviants du consommateur et les moyens engagés pour en limiter les effets portent préjudice aux distributeurs, aux salariés en contact et aux autres consommateurs. Les dommages causés sont à la fois organisationnels, économiques et sociaux. S’appuyant sur 16 entretiens semi-directifs auprès de particuliers et de l’analyse de 12 forums de discussion, cette recherche vise à comprendre l’attitude que les consommateurs ont vis-à-vis des déviances de leurs pairs et le sens qu’ils en donnent. Au vu des résultats, de nombreux consommateurs tolèrent ces comportements et mobilisent les techniques de neutralisation, associées aux injustices distributive et procédurale, pour les justifier. Pour désamorcer une telle logique de défense, nous proposons d’associer l’approche éducative aux techniques de contrôle en magasin.
Pilotage des projets d'ERP fondé sur les communautés de pratique : entre architecture hiérarchique et cognitive
Authors: Azan Wilfrid , Bootz Jean-Philippe 
Published: February 2015

Nous nous intéressons dans cette recherche aux ERP, qui en tant que référentiel informationnel commun, relient les utilisateurs dans et en dehors de l’organisation, et visent à épouser au mieux les pratiques, les savoirs et les compétences qui alimentent l’organisation. Certains travaux laissent apparaître les liens étroits qu’entretiennent les SI (en particulier l’ERP) et la dimension cognitive de la firme en étant potentiellement source de rigidifications, de destructions mais aussi de partage de représentations (Ciborra, 2000 ; Levina et Vaast, 2005). L’étude, de nature interprétative et qualitative menée sur deux ans, met en évidence, sur un plan théorique l’enjeu de l’interconnexion des communautés dans la réussite d’un PERP sur un plan managérial, elle fournit aux praticiens une grille d’analyse explicite les aidant à concevoir et à mettre en œuvre des Projet ERP.
Core Fucosylation of IgG B Cell Receptor Is Required for Antigen Recognition and Antibody Production
Authors: Li Wenzhe , Yu Rui , Ma Biao , Yang Yan , Jiao Xinyan , Liu Yang , Cao Hongyu , Dong Weijie , Liu Linhua , Ma Keli , Fukuda Tomohiko , Liu Qingping , Ma Tonghui , Wang Zhongfu , Gu Jianguo , Zhang Jianing , Taniguchi Naoyuki 
Published: February 2015

Abstract
Ag recognition and Ab production in B cells are major components of the humoral immune response. In the current study, we found that the core fucosylation catalyzed by α1,6-fucosyltransferase (Fut8) was required for the Ag recognition of BCR and the subsequent signal transduction. Moreover, compared with the 3-83 B cells, the coalescing of lipid rafts and Ag-BCR endocytosis were substantially reduced in Fut8-knockdown (3-83-KD) cells with p31 stimulation and then completely restored by reintroduction of the Fut8 gene to the 3-83-KD cells. Indeed, Fut8-null (Fut8−/−) mice evoked a low immune response following OVA immunization. Also, the frequency of IgG-producing cells was significantly reduced in the Fut8−/− spleen following OVA immunization. Our results clearly suggest an unexpected mode of BCR function, in which the core fucosylation of IgG-BCR mediates Ag recognition and, concomitantly, cell signal transduction via BCR and Ab production.
Harmful effects of nicotine
Authors: Mishra Aseem , Chaturvedi Pankaj , Datta Sourav , Sinukumar Snita , Joshi Poonam , Garg Apurva 
Published: February 2015

AbstractWith the advent of nicotine replacement therapy, the consumption of the nicotine is on the rise. Nicotine is considered to be a safer alternative of tobacco. The IARC monograph has not included nicotine as a carcinogen. However there are various studies which show otherwise. We undertook this review to specifically evaluate the effects of nicotine on the various organ systems. A computer aided search of the Medline and PubMed database was done using a combination of the keywords. All the animal and human studies investigating only the role of nicotine were included. Nicotine poses several health hazards. There is an increased risk of cardiovascular, respiratory, gastrointestinal disorders. There is decreased immune response and it also poses ill impacts on the reproductive health. It affects the cell proliferation, oxidative stress, apoptosis, DNA mutation by various mechanisms which leads to cancer. It also affects the tumor proliferation and metastasis and causes resistance to chemo and radio therapeutic agents. The use of nicotine needs regulation. The sale of nicotine should be under supervision of trained medical personnel.
Tobacco-related knowledge, attitudes, and practices among urban low socioeconomic women in Mumbai, India
Authors: Majmudar V Parishi , Mishra A Gauravi , Kulkarni V Sheetal , Dusane R Dusane , Shastri S Surendra 
Published: February 2015

Abstract
Context: Tobacco use is an important health issue globally. It is responsible for a large number of diseases and deaths in India. Female tobacco users have additional health risks. Aims: The aim was to assess changes in pre and post-intervention tobacco-related knowledge, attitudes, and practices among women from urban low socioeconomic strata, after three rounds of interventions. Subjects and Methods: A structured questionnaire was used to interview women living in low socioeconomic housing clusters in Mumbai, regarding their tobacco consumption, attitudes, and practices, by Medical Social Workers. These data were entered into IBM SPSS Statistics, version 20 and analysed. Interventions for tobacco cessation were provided 3 times over a span of 9 months, comprising of health education and counseling. Post-intervention questionnaire was introduced at 12 months. Results: There was statistically significant improvement in the knowledge of women, following the interventions, with particular reference to poor oral hygiene and tobacco use being main cause of oral cancer (P = 0.007), knowledge of ill effects of second hand smoke (P = 0.0001), knowledge about possibility of early detection of oral cancer (P = 0.0001), perception of pictorial and written warnings on tobacco products (P = 0.0001), and availability of help for quitting tobacco (P = 0.024). Conclusion: The prevalence of smokeless tobacco use is very high among urban women from lower socioeconomic strata. Therefore, tobacco awareness programs and tobacco cessation services tailor made for this group of women must be planned and implemented.
Neoadjuvant chemotherapy in advanced epithelial ovarian cancer: A survival study
Authors: Baruah Upasana , Barmon Debabrata , Kataki Amal Chandra , Deka Pankaj , Hazarika Munlima , Saikia Bhargab J. 
Published: February 2015

Abstract
Context: Patients with advanced ovarian cancer have a poor prognosis in spite of the best possible care. Primary debulking surgery has been the standard of care in advanced ovarian cancer; however, it is associated with high mortality and morbidity rates as shown in various studies. Several studies have discussed the benefit of neoadjuvant chemotherapy in patients with advanced ovarian cancer. Aims: This study aims to evaluate the survival statistics of the patients who have been managed with interval debulking surgery (IDS) from January 2007 to December 2009. Materials and Methods: During the period from January 2007 to December 2009, a retrospective analysis of 104 patients who underwent IDS for stage IIIC or IV advanced epithelial ovarian cancer at our institute were selected for the study. IDS was attempted after three to five courses of chemotherapy with paclitaxal (175 mg/m 2 ) and carboplatin (5-6 of area under curve). Overall survival (OS) and progression free survival (PFS) were compared with results of primary debulking study from existing literature. OS and PFS rates were estimated by means of the Kaplan-Meier method. Results were statistically analyzed by IBM SPSS Statistics 19. Results: The median OS was 26 months and the median PFS was 18 months. In multivariate analysis it was found that both OS and PFS was affected by the stage, and extent of debulking. Conclusions: Neoadjuvant chemotherapy, followed by surgical cytoreduction is a promising treatment strategy for the management of advanced epithelial ovarian cancers.
Time from last chemotherapy to death and its correlation with the end of life care in a referral hospital
Authors: Karim Syed Mustafa , Zekri Jamal , Abdelghany Ehab , Dada Reyad , Munsoor Husna , Ahmad Imran 
Published: February 2015

Abstract
Background: A substantial number of cancer patients receive chemotherapy until the end of life (EoL). Various factors have been shown to be associated with receipt of chemotherapy until near death. In this study, we determine our average time from last chemotherapy to death (TLCD) and explore different factors that may be associated with decreased TLCD. Materials and Methods: A retrospective review of medical records of adult cancer patients who received chemotherapy during their illness and died in our hospital between January 2010 and January 2012 was conducted. Chi-square test and t-test were used to examine the correlation between selected factors and use of chemotherapy within 60 days of death. Multivariate analysis was used to test independent significance of factors testing positive in univariate analysis. Kaplan-Meier method was used to perform survival analysis. Results: Of the 115 cancer patients who died in the hospital, 41 (35.6%) had TLCD of 60 days or less. Patients with better performance status and those dying under medical oncology service were more likely to be in this group of patients. Univariate analysis showed that these patients were less likely to have palliative care involvement, were more likely to die of treatment related causes, and more likely to have died in the Intensive Care Unit. Multivariate analysis confirmed lack of palliative care involvement and better performance status as independent factors for TLCD less than 60 days. Survival analyses showed that patients with palliative care involvement and those dying under palliative care service were likely to have significantly longer TLCD. Conclusions: Cancer patients who have no involvement of palliative care team in their management tend to receive chemotherapy near the EoL, have more aggressive EoL care, and have higher risk of dying die from treatment related complications. Palliative care should be involved early in the care of cancer patients.
Commentary on 19 th annual scientific meeting of the Society for Neuro-Oncology
Authors: Jalali Rakesh 
Published: February 2015

AbstractThe Society for Neuro-Oncology (SNO) is the premier organization dedicated to the cause of central nervous system (CNS) tumors. Although it is primarily located in North America, it attracts considerable memberships from all over the world with truly multi-disciplinary representations from not only neuro-oncology, neurosurgery, radiation oncology, medical oncology and basic scientists, but also in recent years from imaging, psychology, epidemiology, public health and industry, etc. SNO annual meetings are very much looked forward to with presentations of the latest cutting edge data as well as several educational sessions for trainees and updates for senior members too. The meeting is unique in the way that almost the entire scientific agenda is based on submitted abstracts with very few invited lectures.
Updates from the 2014 San antonio breast cancer symposium
Authors: Dawood Shaheenah 
Published: February 2015

AbstractThe san antonio breast cancer syposium (SABCS 2014) was an exciting one this year. Data from the SOFT trial was presented that had potential implications on the treatment of pre menapausal women with hormone receptor positive breast cancer. In a phase II trial fulvestrant was found to significantly improve progression free and overall survival compared to anastrazole in the first line treatment of women with hormone receptor positive metastatic breast cancer. We saw a number of intersting abstracts looking at trying to refine the role of platinums and exploring the role of blocking PD-1 among women with triple receptor negative breast cancer. We also saw the results of a number of trials trying to refine standard chemotherapeutic regimens. Here we will review some fon the most interesting abstracts presented this year at SABCS 2014.
Addressing Radicalisation into the Classroom - A New Approach to Teacher and Pupil Learning
Authors: Reeves Jane , Sheriyar Alamgir 
Published: February 2015

<p>This article examines one response to the UK Government’s directive that radicalisation and extremism should be tackled in all UK secondary schools. The small scale study is set in the broader literature of teaching often difficult Personal, Social and Health Education (PSHE) topics to young people in secondary school, and also the use of simulations as tools for learning in the classroom. It analyses the responses of teachers to being trained with, and using, ‘Zak’ a bespoke research-based simulation on the radicalisation process. An analysis of the teachers’ responses indicated recognition that the principles of adults manipulating children, whether for sexual gratification or radicalisation, are considered to be very important topics for staff working with young people in school settings to address. It was also recognised as a flexible learning tool enabling various pathways to be explored with young people in lessons, addressing the many aspects of e-safety, not just radicalisation. Additionally, the teachers remarked that the social media ‘Facebook’ format of the simulation was appreciated by the young people, and this appeal resulted in their immersion with it as a teaching aid. The comprehensive delivery of the ‘Zak’ package into schools was also significant. Staff reported that the inter-professional training delivered by specialist police trainers, and the accompanying materials, enhanced the learning and confidence of the teachers on this multi-faceted and complex topic.</p>
Platelet serotonin modulates immune functions
Authors: Mauler M. , Bode C. , Duerschmied D. 
Published: February 2015

SummaryThis short review addresses immune functions of platelet serotonin. Platelets transport serotonin at a high concentration in dense granules and release it upon activation. Besides haemostatic, vasotonic and developmental modulation, serotonin also influences a variety of immune functions (mediated by different serotonin receptors). First, platelet serotonergic effects are directed against invading pathogens via activation and proliferation of lymphocytes, modulation of cytokine release, and recruitment of neutrophils to sites of acute inflammation by induction of selectin expression on endothelial cells. Second, serotonin levels are elevated in autoimmune diseases, such as asthma or rheumatoid arthritis, and during tissue regeneration after ischemia of myocardium or brain. Specific antagonism of serotonin receptors appears to improve survival after myocardial infarction or sepsis and to attenuate asthmatic attacks in animal models. It will be of great clinical relevance if these findings can be translated into human applications. In conclusion, targeting immune modulatory effects of platelet serotonin may provide novel therapeutic options for common health problems.
Witwasonderzoeken zonder aantoonbaar gronddelict
Authors: Rozemeijer J.P. 
Published: February 2015

Dutch money laundering investigations without a link to the predicate offence
In Dutch criminal money laundering investigations there is no need to fully proof the predicate offence. When a criminal suspicion of money laundering exists without a direct connection to the predicate offence it’s the suspect who must prove the legal origin of his income or possessions. If the suspect doesn’t succeed in this, the judge will rule that the origin has to be criminal. This article shows in six steps how judges rule in this kind of cases and how an investigation can be done. These six steps are combined with examples from recent jurisprudence. The goal of this article is to raise awareness on this subject in order to operate more efficiently and effectively in money laundering investigations.
Hoe
effectief is het antiwitwasbeleid in elke
EU-lidstaat?
Authors: Ferwerda J. , Unger B. 
Published: February 2015

How effective are anti-money laundering policies in each EU Member State?
All EU Member States developed anti-money laundering policies based on EU directives and FATF recommendations. While uniformity in this policy area is needed for international cooperation, the different countries are facing different money laundering challenges and interpret the goal of anti-money laundering policy quite differently. This article analyses the money laundering threat in each EU Member State and the effectiveness of the corresponding policy reaction. Furthermore, the authors identify four types of anti-money laundering policy in the EU and classify each country in one of the four types by using the statistical method of cluster analysis.
Prognosis of Ti abundance in Sinus Iridum using a nonlinear analysis of Chang' E‐1 Interference Imaging Spectrometer imagery
Authors: Tingyan Xing , Fujiang Liu , Li Liu , Chan Li , Ying Zhang , Le Qiao , Rong Yang , Xiaopo Zheng , Meng Zhu , Qi Zhang 
Published: February 2015

AbstractWe report here on the relationship between titanium abundance and its spectral features on the Moon, using 36 craters exposed in Sinus Iridum, a landing site for China's Lunar Exploration Program. Six absorption parameters (full width at half maximum, absorption depth (D), absorption position (λ), absorption area (A), absorption asymmetry (S), and (Rmin)) at the wavelength of 500–550 nm were computed, and the lowest reflectance values (Rmin) to characterize the properties of titanium abundance and its spectral features were calculated. The correlation between Rmin and TiO2 abundance calculated by Clementine multispectral images is 0.812, and a second‐order polynomial fits the data better with a correlation of 0.837. The TiO2 abundance inversed by the Chang' E‐1 Interference Imaging Spectrometers (IIM) data is thus relatively higher than that revealed by the Clementine data. This good correlation between Rmin and TiO2 abundance may thus be used very effectively to estimate the Ti distribution on the surface of the Moon by IIM hyperspectral data.
Lightning locating systems: Insights on characteristics and validation techniques
Authors: Nag Amitabh , Murphy Martin J. , Schulz Wolfgang , Cummins Kenneth L. 
Published: February 2015

AbstractGround‐based and satellite‐based lightning locating systems are the most common ways to detect and geolocate lightning. Depending upon the frequency range of operation, LLSs may report a variety of processes and characteristics associated with lightning flashes including channel formation, leader pulses, cloud‐to‐ground return strokes, M‐components, ICC pulses, cloud lightning pulses, location, duration, peak current, peak radiated power and energy, and full spatial extent of channels. Lightning data from different types of LLSs often provide complementary information about thunderstorms. For all the applications of lightning data, it is critical to understand the information that is provided by various lightning locating systems in order to interpret it correctly and make the best use of it. In this study, we summarize the various methods to geolocate lightning, both ground‐based and satellite‐based, and discuss the characteristics of lightning data available from various sources. The performance characteristics of lightning locating systems are determined by their ability to geolocate lightning events accurately with high detection efficiency and with low false detections and report various features of lightning correctly. Different methods or a combination of methods may be used to validate the performance characteristics of different types of lightning locating systems. We examine these methods and their applicability in validating the performance characteristics of different LLS types.