bluuebunny/crossref_metadata_2025_split huggingface dataset:
Una experiencia innovadora de integración médico-social en la formación de médicos
Authors: Lozano Pérez Fernando Raymundo 
Published: June 2024

En el presente artículo se exponen algunos antecedentes sobre el papel que juegan los determinantes sociales de la salud, su influencia en la práctica de la medicina y en la educación médica; cómo estos se han convertido en la piedra angular en el análisis de los problemas de salud actuales y el aval que representa que la Organización Mundial de la Salud (OMS) haya adoptado esta perspectiva y sea una recomendación para que los gobiernos las tomen en cuenta, no solo en el desarrollo de sus políticas de salud, sino como fundamento en la formación de recursos humanos en salud. Buscando que los futuros médicos logren una comprensión integral del proceso salud-enfermedad y la necesidad de cambio de perspectivas, habilidades y actitudes.
Se analizan algunos fundamentos y principios de experiencias que han intentado llevar a los planes de estudio y currículos, esta nueva visión, sus logros y dificultades.
A partir de un análisis crítico y autocrítico de expe riencias propias y externas, planteamos la necesidad de superar debilidades en la comprensión del papel de las ciencias sociales y humanas y su integración en la Carrera de Médico Cirujano. Describimos a grandes rasgos nuestra experiencia de cuatro años de vinculación de estas en el currículo y práctica en la formación de nuestros estudiantes con la creación e implementación de un Seminario de Integración Sociopsicobiológica en los cuatro primeros semestres de la carrera dentro del nuevo plan de estudios de la Carrera de Médico Cirujano (2016), de la Facultad de Estudios Superiores Iztacala, de la Universidad Nacional Autónoma de México. Por último, hacemos algunas observaciones previas a una evaluación del seminario, en el marco de una evaluación curricular que se encuentra en proceso de revisión.
UJI KADAR ABU PAKAN TERNAK DAERAH KABUPATEN SIJUNJUNG DENGAN METODE GRAVIMETRI
Authors: Komala Sari Irma Septia 
Published: June 2024

Feed is anything that can be given as a source of energy and nutrients. The organic matter content of a feed depends on other components such as dry matter and ash. Gravimetry is a quantitative analysis used to determine the total ash content. This experiment used a completely randomized design. Based on the observation table which presents many samples in Sijunjung, feed samples processed from various different brands meet good nutritional standards for animal nutrition according to SNI standards.
Numerical Investigation of Indentation-Induced Residual Stresses and their Effect on J-Integral and Crack Propagation
Authors: Baltach Abdelghani , Khelil Foudil , Djebli Abdelkader , Benhamena Ali , Chaouch Mohamed Ikhlef , Bendouba Mostefa 
Published: June 2024

Abstract
This work presents an analysis of the effect of ball indentation on fatigue crack growth. The main objective is to assess the effectiveness of indentation, particularly its influence on the J-integral, as a fracture criterion governing fracture toughness. Using the finite element method in Abaqus 6.14, we analyzed the residual stresses induced by indentation at different positions along the predicted line of crack propagation and calculated the J-integral. The results highlight that indentation at the crack tip position significantly reduces the J-integral compared to non-indented structures, demonstrating its potential to extend the lifespan of cracked components by delaying crack propagation. The findings underscore the practical application of ball indentation as a viable technique to retard crack growth, contributing to the longevity of cracked components and, consequently, structural integrity. This analysis revealed a crack propagation retardation gain of up to 56%.
Imprints of Graphene Nanocomposites Towards Energy Storage Potential of Lithium Ion Batteries—State of the Art and Perspectives
Authors: Kausar Ayesha , Ahmad Ishaq 
Published: June 2024

Abstract
This state-of-the-art article is designed to cover essential aspects of graphene based nanomaterials for energy storage purposes. Graphene is, a unique nanocarbon, one atom thick nanosheet made up of sp2 hybridized carbon atoms. Graphene has been focused for various technical energy related devices and systems owing to remarkable structure and properties. In energy storage applications, graphene has been applied for varying devices like supercapacitors, fuel cell and batteries. Important utilization of graphene and derived nanocomposites have been observed for lithium (Li) ion batteries. In this context, graphene has been found to offer superior surface area, electron conduction, electrochemical properties, charge or energy density, reversible capacity, rate capacity, cyclic stability, charge-discharge behavior, and other progressive characteristics for effectual energy or charge storage. In addition, graphene derived nanomaterials have been researched for structural, morphological, mechanical, thermal, and other physical characteristics. Hence, graphene and nanocomposites have been reported as efficient Li ion battery electrode or electrolyte material. Future progress on designing new efficient graphene derived nanocomposites and three dimensional graphene based nanomaterials may overcome the challenges towards the formation of high performance battery electrode or electrolyte materials.
Penetrating Keratoplasty in Children
Authors: Balchev G. , Balabanov C. , Murgova S. 
Published: June 2024

Abstract
Keratoplasty is one of the most common tissue transplants. However, its application in children remains a high-risk procedure. The child eyeball is smaller, the cornea and sclera are more elastic, a higher pressure on the vitreous body and often other malformations of the anterior eye segment are present, all of which makes it a significantly more difficult intervention than that in adults. The aim of the report is to present a case of keratoplasty in a child with corneal perforation due to trauma. A 7-year-old child, who fell off a bicycle 4 days ago and hit their eye area, was admitted to the eye diseases clinic. In the clinic, an examination was performed under general anesthesia; a foreign body was removed from the left eye and a perforation of the cornea was established. A penetrating keratoplasty was performed. Two months after the surgery, loosening of the sutures began, and scarring and their gradual removal became necessary. 18 months after the operation, the eye is completely calm and the transplant is transparent. Penetrating keratoplasty in children remains a major challenge for most surgeons. A good collaboration with the parents is necessary to preserve the transparency of the transplant and improve visual acuity.
Fracture into the Abdominal Cavity and the Presence of A Retroauricular Pseudocyst Are Diagnostic of A Partial Ventriculoperitoneal Shunt Dysfunction
Authors: Bal’afif F. , Wibowo O. , Nazwar T. A. , Wardhana D. W. , Mustofa M. 
Published: June 2024

Abstract
Ventriculoperitoneal shunt malfunction is frequently observed, with the ventriculoperitoneal shunt fracture being a prevalent etiology. The occurrence of ventriculoperitoneal shunt malfunction is approximately 40% in the first year after implantation and increases to 50% in the second year. Ventriculoperitoneal shunt fracture accounts for 15% of total ventriculoperitoneal shunt malfunction incidents. Ventriculoperitoneal shunt fractures commonly occur due to calcification, immune reactions, and abrasions. The report describes a 5-year-old child who exhibited ventriculoperitoneal shunt malfunction based on clinical examination and CT scan findings. The patient presented with fever and pain in the postoperative wound located posteriorly to the left ear. Radiographic imaging of the cranium and thoracoabdominal region revealed the presence of a ventriculoperitoneal shunt fracture and a C5 spinal disconnection. Additionally, it was demonstrated that the distal catheter had relocated to the abdominal cavity. The laboratory examination and cerebrospinal fluid analysis yielded normal results. The fractured ventriculoperitoneal shunt was subsequently removed and replaced with a new one. It is important to thoroughly investigate and comprehend ventriculoperitoneal shunt malfunctions, even during routine follow-ups.
Aggressive Angiomyxoma of the Female External Genitalia
Authors: Gincheva D. , Vanov Al. , Gincheva V. 
Published: June 2024

Abstract
Aggressive angiomyxoma (AAM) is a rare and benign mesenchymal tumor that localizes predominantly in the female pelvis. Its invasive growth and local recurrence are challenging for professionals. Histologically, AAM is a tumor with a myxoid stroma that is highly vascular and hypocellular. The diagnosis is made relatively late due to nonspecific symptoms. Treatment of AAM is extensive local surgical excision with intact resection lines. Gonadotropin-releasing hormone agonists are added postoperatively. The prognosis is good and metastasis is rare. We present a case of an aggressive angiomyxoma located in the left greater labial area in a 50-year-old woman. After discussion and informed consent signed by the patient, on 27.01.2023 at the University Hospital “St. Marina” Pleven, the patient was admitted to the hospital. The tumor was extirpated under epidural anaesthesia on the date of the patient&#39;s informed consent. The patient was prescribed postoperative therapy with Zoladex 3,6 mg implant according to the schedule.The patient was subjected to monthly gynecological check-ups for one year after the surgical intervention. To date, no recurrence of the underlying disease has been detected. Long-term results show a good trend. In conclusion, we can say that the optimal treatment of AAM is wide local excision. It is not recommended to aim for radicality because of the risk of postoperative complications. Postoperative administration of GnRH-a is advisable to avoid recurrences. All patients undergo regular follow-up examinations for long-term follow-up.
Sporadic Creutzfeldt–Jakob Disease
Authors: Zhelyazkova S. , Nachev S. , Kalev O. , Tournev I. 
Published: June 2024

Abstract
Sporadic Creutzfeldt–Jakob disease is a rare and fatal human prion disease characterized by a rapidly progressive dementia, myoclonus, cerebellar, pyramidal, extrapyramidal, visual, and psychiatric symptoms. These findings are all non-specific and making diagnosis is often difficult at the symptoms onset, especially in case of atypical clinical and radiological presentation. This case report describes a woman in her 60s, who presented with rapid cognitive decline, confusion, ataxia and electroencephalographic changes compatible with nonconvulsive status epilepticus. Her symptoms progressively worsened and she died 8 weeks after the onset. The two cerebrospinal fluid analyses were normal and no 14-3-3 protein was detected. The brain MRls revealed areas of cortical restricted diffusion involving the right frontal and parietal lobe. The electroencephalographic findings of continuous periodic generalized bi-triphasic complexes, typical for sporadic Creutzfeldt–Jakob disease, were detected 1 month after the onset. Sporadic Creutzfeldt–Jakob disease was neuropathologically confirmed. Although sporadic Creutzfeldt–Jakob disease is a rare neurodegenerative disease, it should be considered in the differential diagnosis of all cases with unexplained and rapid cognitive decline and confusion, along with ataxia, pyramidal/ extrapyramidal signs, myoclonus and dysphagia.
Comparison of growth performance, pasture usage, carcass yield and breast meat characteristics of two different slow-growing broiler genotypes kept in the free-range
Authors: Sözcü Arda , İpek Aydın , Gündüz Merve , Gunnarsson Stefan 
Published: June 2024

Abstract
Consumers’ interest in animal welfare-friendly systems with outdoor access is growing and therefore the necessity has arisen for genotypes suitable for free-range systems. This study aimed to investigate the suitability of two slow-growing broiler genotypes by comparing growth performance, pasture usage, carcass yield and breast meat traits. Two slow growing genotypes Hubbard ISA Red JA-57 (n= 240) and Sasso XL44 × SA51A (n= 240), were raised in free-range system for 63 days, and their suitability was assessed. Body weight, feed consumption and feed conversion rate were weekly determined. To assess the pasture usage (interior, buffer and outer zones), the observations were performed twice a day. The total of 60 birds (n: 30 broilers/genotype) were randomly sampled for slaughter process at 63rd day of age, and subsequently breast muscle samples were processed for the physical quality and chemical composition parameters of the meat.
At 63 days of age, the final body weight was found to be 2918.0 g and 3253.6 g in Hubbard and Sasso birds respectively (P<0.001). Also, a higher body weight gain was observed for Sasso birds than Hubbard birds as well (3210.2 vs. 2874.8 g, P<0.001). The broilers preferred to pasture at the interior zone rather than buffer and outer zones (P<0.001), and usually in the morning (27.54%) than in the evening (20.93%, P=0.010). The average slaughter weight, carcass weight and carcass yield were higher in Sasso genotype (3296.7, 2540.4 g, 77.1%, respectively] at 63 days of age compared to Hubbard genotype (2878.3, 2192.3g and 76.2%, respectively, P<0.001). The weight and relative weight of breast were also higher in Sasso (746.2 g and 29.4% respectively) than the Hubbard genotype (617.6 g and 28.2% respectively, P>0.001). These findings could help free-range broiler producers to choose a more suitable genotype according to the final body weight, feed efficiency, pasture usage, carcass yield, and breast meat characteristics.
A mouse model of uterine exposure to long-term hyperglycemia and a high-fat diet*
Authors: Zglejc-Waszak Kamila , Korytko Agnieszka , Pomianowski Andrzej , Wojtkiewicz Joanna , Wąsowicz Krzysztof , Juranek Judyta K. 
Published: June 2024

Abstract
A growing body of literature has shown that type 1 diabetes (T1D) and high-fat diet (HFD) affect female reproductive function and may be involved in a chronic inflammatory state. Our previous studies indicated that T1D as well as HFD may evoke perturbations in the receptor for advanced glycation end products (RAGE) signaling pathway. The aim of the study was to determine the amount of RAGE protein and its proinflammatory ligands in uterine tissues harvested from T1D and HFD/pre-diabetic mice (n = 5 per group). We sought the impact of T1D and HFD on the activity of the RAGE signaling pathway in uterine tissues during the estrous cycle. The abundance of RAGE and its ligands were estimated using immunohistochemical staining. However, we also performed nerve conduction velocity studies to confirm diabetic neuropathy. The highest amount of RAGE and its ligands were observed in uterine tissues of T1D mice. Moreover, myometrial activity of the RAGE signaling pathway was increased in HFD in comparison to the control group (P≤0.05). We observed a strong relationship between RAGE, Nε-(carboxymethyl)lysine (CML) and tumor necrosis factor alpha (TNFα) proteins in mice myometrium. These data suggest that T1D and HFD could modulate the activity of RAGE and thus RAGE signaling pathway in uterine tissues during estrous cycle. Long-term diabetes and HFD may induce malfunctions in the uterine milieu. In the future RAGE protein may serve as a molecular marker in the diagnosis of malfunctions in pre- and diabetic uterus milieu.
Altered miRNA pattern in canine mammary tumors - pilot study
Authors: Gherman Luciana-Mădălina , Zanoaga Oana , Budisan Liviuta , Isachesku Ekaterina , Lajos Raduly , Ciocan Cristina , Braicu Cornelia , Atanasov Atanas G. , Berindan-Neagoe Ioana 
Published: June 2024

Abstract
Canine mammary tumors (CMTs) represent a prevalent malignancy in female dogs. MicroRNAs (miRNAs) have emerged as critical regulators of gene expression and are implicated in various cancer types, including CMTs. This study aimed to investigate the altered miRNA expression patterns in CMTs and their potential role in tumorigenesis. We analyzed miRNA profiles in a cohort of CMT samples and matched normal tissues using a custom canine panel microarray slide (Agilent technology). The bioinformatics analysis overlapped the altered miRNA signature in CMT with human breast cancer miRNA (TCGA patient cohort). The biological significance of this altered miRNA signature was evaluated using Ingenuity Pathway Analysis. Our results revealed a distinctive miRNA expression signature associated with CMTs compared to normal mammary tissues, and when overlapped with human breast cancer miRNA data (TCGA cohort), we identified a common signature composed of one overexpressed transcript and eight downregulated transcripts. In conclusion, our study provides comprehensive insights into the altered miRNA expression patterns in CMTs, shedding light on their potential contribution to the pathogenesis of these tumors. Further investigation into the specific roles of these dysregulated miRNAs is warranted to elucidate their precise involvement in CMT progression and to explore their therapeutic implications.
Energy Recovery from Ice Waste Heat Using Thermoelectric Generators
Authors: Iavnic Tudor , Puiu Dragoş , Popescu Aristotel 
Published: June 2024

Abstract
In recent times, people pay more attention to global warming because they realise its impact on the environment and human life. The main factor that influences it are the emissions produced by the transportation industry. Automobiles are one of the biggest source CO2 emissions. Because the engine efficiency is low, most of the energy produced is lost as heat. If the lost heat is recovered and transformed to electrical energy it could power some of the automobile systems, thus reducing the fuel consumption and CO2 emissions. Among the researched power generation technologies, one of the most advantageous in this situation is the thermoelectric generator (TEG). TEGs take advantage of Seebeck effect to convert low temperature heat into electricity using materials similar to thermocouples. The purpose of this paper is to provide a comprehensive overview of the TEG, including its operational principle, the experiments conducted to test it, the materials used in its construction, and the methods employed to improve its performance.
Applications of Axiomatic Design in the Project Management of New Product Development – A Literature Research
Authors: Nicolau Mihaela 
Published: June 2024

Abstract
The article investigates the applications of Axiomatic Design to the Project Management of new product development as it currently stands based on publicly available materials. Project Management is a collection of processes tailored to fit an application. The research focused on processes associated to Project Management, and it was less focused on product design. The results of the investigation indicate that the application of Axiomatic Design to Project Management would be useful and would lead to improvements of projects’ success and business’s Return-on-Investment. The researcher concludes that product requirements could be used to model a uniform approach to most processes used in Project Management but, depending on the project complexities, a smaller scope approach is more appropriate depending on company’s internal organization of work. It will be beneficial to either project management practitioner or any business manager to have a framework easy to utilize in designing processes as needed for the successful completion of any project.
Overview on Bearing Manufacturers Research and Development Directions
Authors: Chitariu Dragoş-Florin , Eduţanu Florin-Daniel , Oancea Lucian , Mihai Constantin-Gheorghe , Bişoc Cristiana 
Published: June 2024

Abstract
The paper presents an overview of development directions and market interest declared by the largest and relevant manufacturers of bearings worldwide. The general directions of improving the quality of and durability of bearings remained a current research field but also adding different products and services (such as remanufacturing of bearings and conditioning monitoring product and services) are in the manufacturers focus. Special considerations are on introducing AI technologies in the decision making process and process coordination in bearing manufacturing, also electrification is considered to be a large part of future sales in automotive and various electric drive units.
Indigenous Place Names: A Literary Toponomastics Study of Suburb Names in Cape Coast
Authors: Nkansah Samuel Kwesi , Bonsu Emmanuel Mensah 
Published: June 2024

Abstract
Most toponomastics research has ignored the importance of indigenous places as sites for identity and other cultural and social significance. Using Cape Coast as a historical site of the transatlantic slave trade, this study explores the origin, meanings and relevance of indigenous place names in the suburbs of Cape Coast, Ghana. Through an interdisciplinary approach that synergizes an interview with a chief, who is a prosopographer, historical documents, and literary sources, this study traces the city’s evolution from its ancestral hunting origins. The findings revealed that Cape Coast’s identity is encapsulated in the indigenous names, which point out the complex dynamics of culture, geography, identity and power. The names reference landmarks, events, environment and communities, transforming the city itself into a living archive with historical relevance. The literary interpretations uncovered metaphorical meanings encoded in some toponyms. Tracing connections across people, events, geography and time, these names reveal an interconnection often obscured by colonial ruptures. Based on these findings, there is a need to preserve the indigenous place names to foster intergenerational connections to the city’s storied landscape. The study contributes to Critical Toponymy theory and empirical insights into using indigenous toponyms to decolonize urban heritage.
Implementing multilevel environmental governance in Košice region (Slovakia): interactions between regional policies, institutional management, and individuals’ needs
Authors: Dobrucká Lucia , Mynaříková Lenka 
Published: June 2024

Abstract
Multilevel governance concept has been increasingly coined by the EU environmental and climate adaptation policies, but its implementation in some countries faces the heavy dominance of state-level perspective in public discourse. This article explores interactions between regional policies (based especially on the Adaptation Strategy, the Nature Recovery Plan, and their action plans), institutional management (how public institutions approached environmental and climate adaptation needs through the design of their institutional areas), and individual needs (how individuals were considered and involved). Methodology includes the content analysis of documents framing regional policies and a questionnaire collected during September 2021 (in which 150 public institutions were addressed and 87 of them responded). Data show that even though the Košice region strived for holistic approach, cooperation, and participation, the proclaimed values and the real-life situation differed. The developed regional strategy was rather unbalanced, projects implemented by individual institutions seemed to be driven by financial aids rather than real needs, and individuals’ needs as well as their participation on implementing environmental policies were often neglected.