bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tecnologia da informação, criação e compartilhamento do conhecimento: um estudo do sistema integrado de segurança pública na diretoria de investigações criminais de Santa Catarina
Authors: Silva Indianara , Mussi Clarissa Carneiro 
Published: June 2014

The aim of this study is to analyze the role of information technology in the field of operation of public safety in the Brazilian state of Santa Catarina. More specifically, it was based on the following research problem: how does the use of information technology in the area of public safety influence the creation and sharing of knowledge in criminal investigations in the civilian police force, by means of police inquiry? From a methodological point of view, the study was conducted using a qualitative approach, having the character of a case study. The data collection techniques included the use of questionnaires, semi-structured interviews and the analysis of documentation and physical artifacts. As far as the treatment and interpretation of the data is concerned, content analysis techniques were employed. The study showed that the use of information technology can provide actions which facilitate sharing, mainly of explicit knowledge, and which, as a result, characterize activities related to criminal investigation and the launching of police inquiries. These activities are lacking in strategies that provide the sharing of tacit knowledge and consequently the creation of knowledge. Moreover, it was found that the contribution of technology to knowledge creation and sharing in the criminal investigation process also depends on other variables of a contextual (e.g. institutional policies) and individual nature (e.g. resistance).
Los desarrolladores de libros apps. infantiles y juveniles: características, perspectivas y modelo de negocio
Authors: Sanz Pilar Neila , García Rodríguez Araceli 
Published: July 2014

El mercado de Literatura Infantil y Juvenil en España se ha mantenido en auge en las últimas décadas y ha sufrido un incremento exponencial desde la introducción de las TIC’s, la adquisición de contenidos digitales a través de Internet y la implantación de la edición digital, incluyendo la integración de objetos multimedia en los libros electrónicos, especialmente aquellos dedicados al público infantil y juvenil. Esta investigación pretende mostrar una breve radiografía de los desarrolladores de libros aplicaciones destinados a niños y jóvenes en España, con la finalidad de conocer las características intrínsecas que definen a estas compañías, analizar los cambios producidos en el modelo de negocio a través de la producción, la comercialización y la promoción de los libros aplicaciones; y delinear las perspectivas de futuro tanto de estas empresas como de los libros aplicaciones en el subsector de la Literatura Infantil y Juvenil española.
Effects of a strong ICME on the Martian ionosphere as detected by Mars Express and Mars Odyssey
Authors: Morgan D. D. , Diéval C. , Gurnett D. A. , Duru F. , Dubinin E. M. , Fränz M. , Andrews D. J. , Opgenoorth H. J. , Uluşen D. , Mitrofanov I. , Plaut J. J. 
Published: July 2014

AbstractWe present evidence of a substantial ionospheric response to a strong interplanetary coronal mass ejection (ICME) detected by the Mars Advanced Radar for Subsurface and Ionosphere Sounding (MARSIS) on board the Mars Express (MEX) spacecraft. A powerful ICME impacted the Martian ionosphere beginning on 5 June 2011, peaking on 6 June, and trailing off over about a week. This event caused a strong response in the charged particle detector of the High‐Energy Neutron Detector (HEND) on board the Odyssey spacecraft. The ion mass spectrometer of the Analyzer of Space Plasmas and Energetic Atoms instrument on MEX detected an increase in background counts, simultaneous with the increase seen by HEND, due to the flux of solar energetic particles (SEPs) associated with the ICME. Local densities and magnetic field strengths measured by MARSIS and enhancements of 100 eV electrons denote the passing of an intense space weather event. Local density and magnetosheath electron measurements and remote soundings show compression of ionospheric plasma to lower altitudes due to increased solar wind dynamic pressure. MARSIS topside sounding of the ionosphere indicates that it is extended well beyond the terminator, to about 116° solar zenith angle, in a highly disturbed state. This extension may be due to increased ionization due to SEPs and magnetosheath electrons or to plasma transport across the terminator. The surface reflection from both ionospheric sounding and subsurface modes of the MARSIS radar was attenuated, indicating increased electron content in the Mars ionosphere at low altitudes, where the atmosphere is dense.
Seasonally resolved ice core records from West Antarctica indicate a sea ice source of sea‐salt aerosol and a biomass burning source of ammonium
Authors: Pasteris Daniel R. , McConnell Joseph R. , Das Sarah B. , Criscitiello Alison S. , Evans Matthew J. , Maselli Olivia J. , Sigl Michael , Layman Lawrence 
Published: July 2014

AbstractThe sources and transport pathways of aerosol species in Antarctica remain uncertain, partly due to limited seasonally resolved data from the harsh environment. Here, we examine the seasonal cycles of major ions in three high‐accumulation West Antarctic ice cores for new information regarding the origin of aerosol species. A new method for continuous acidity measurement in ice cores is exploited to provide a comprehensive, charge‐balance approach to assessing the major non‐sea‐salt (nss) species. The average nss‐anion composition is 41% sulfate (SO42−), 36% nitrate (NO3−), 15% excess‐chloride (ExCl−), and 8% methanesulfonic acid (MSA). Approximately 2% of the acid‐anion content is neutralized by ammonium (NH4+), and the remainder is balanced by the acidity (Acy ≈ H+ − HCO3−). The annual cycle of NO3− shows a primary peak in summer and a secondary peak in late winter/spring that are consistent with previous air and snow studies in Antarctica. The origin of these peaks remains uncertain, however, and is an area of active research. A high correlation between NH4+ and black carbon (BC) suggests that a major source of NH4+ is midlatitude biomass burning rather than marine biomass decay, as previously assumed. The annual peak in excess chloride (ExCl−) coincides with the late‐winter maximum in sea ice extent. Wintertime ExCl− is correlated with offshore sea ice concentrations and inversely correlated with temperature from nearby Byrd station. These observations suggest that the winter peak in ExCl− is an expression of fractionated sea‐salt aerosol and that sea ice is therefore a major source of sea‐salt aerosol in the region.
Field‐calibrated model of melt, refreezing, and runoff for polar ice caps: Application to Devon Ice Cap
Authors: Morris Richard M. , Mair Douglas W. F. , Nienow Peter W. , Bell Christina , Burgess David O. , Wright Andrew P. 
Published: July 2014

AbstractUnderstanding the controls on the amount of surface meltwater that refreezes, rather than becoming runoff, over polar ice masses is necessary for modeling their surface mass balance and ultimately for predicting their future contributions to global sea level change. We present a modified version of a physically based model that includes an energy balance routine and explicit calculation of near‐surface meltwater refreezing capacity, to simulate the evolution of near‐surface density and temperature profiles across Devon Ice Cap in Arctic Canada. Uniquely, our model is initiated and calibrated using high spatial resolution measurements of snow and firn densities across almost the entire elevation range of the ice cap for the summer of 2004 and subsequently validated with the same type of measurements obtained during the very different meteorological conditions of summer 2006. The model captures the spatial variability across the transect in bulk snowpack properties although it slightly underestimates the flow of meltwater into the firn of previous years. The percentage of meltwater that becomes runoff is similar in both years; however, the spatial pattern of this melt‐runoff relationship is different in the 2 years. The model is found to be insensitive to variation in the depth of impermeable layers within the firn but is very sensitive to variation in air temperature, since the refreezing capacity of firn decreases with increasing temperature. We highlight that the sensitivity of the ice cap's surface mass balance to air temperature is itself dependent on air temperature.
Responsive Mesoporous Photonic Cellulose Films by Supramolecular Cotemplating
Authors: Giese Michael , Blusch Lina K. , Khan Mostofa K. , Hamad Wadood Y. , MacLachlan Mark J. 
Published: July 2014

AbstractCellulose‐based materials have been and continue to be exceptionally important for humankind. Considering the bioavailability and societal relevance of cellulose, turning this renewable resource into an active material is a vital step towards sustainability. Herein we report a new form of cellulose‐derived material that combines tunable photonic properties with a unique mesoporous structure resulting from a new supramolecular cotemplating method. A composite of cellulose nanocrystals and a urea–formaldehyde resin organizes into a chiral nematic assembly, which yields a chiral nematic mesoporous continuum of desulfated cellulose nanocrystals after alkaline treatment. The mesoporous photonic cellulose (MPC) films undergo rapid and reversible changes in color upon swelling, and can be used for pressure sensing. These new active mesoporous cellulosic materials have potential applications in biosensing, optics, functional membranes, chiral separation, and tissue engineering.
DNA‐Catalyzed Lysine Side Chain Modification
Authors: Brandsen Benjamin M. , Velez Tania E. , Sachdeva Amit , Ibrahim Nora A. , Silverman Scott K. 
Published: July 2014

AbstractCatalyzing the covalent modification of aliphatic amino groups, such as the lysine (Lys) side chain, by nucleic acids has been challenging to achieve. Such catalysis will be valuable, for example, for the practical preparation of Lys‐modified proteins. We previously reported the DNA‐catalyzed modification of the tyrosine and serine hydroxy side chains, but Lys modification has been elusive. Herein, we show that increasing the reactivity of the electrophilic reaction partner by using 5′‐phosphorimidazolide (5′‐Imp) rather than 5′‐triphosphate (5′‐ppp) enables the DNA‐catalyzed modification of Lys in a DNA‐anchored peptide substrate. The DNA‐catalyzed reaction of Lys with 5′‐Imp is observed in an architecture in which the nucleophile and electrophile are not preorganized. In contrast, previous efforts showed that catalysis was not observed when Lys and 5′‐ppp were used in a preorganized arrangement. Therefore, substrate reactivity is more important than preorganization in this context. These findings will assist ongoing efforts to identify DNA catalysts for reactions of protein substrates at lysine side chains.
Small bowel obstruction, incisional hernia and survival after laparoscopic and open colonic resection (LAFA study)
Authors:   the Collaborative LAFA Study Group, Bartels S A L , Vlug M S , Hollmann M W , Dijkgraaf M G W , Ubbink D T , Cense H A , van Wagensveld B A , Engel A F , Gerhards M F , Bemelman W A , Cuesta M A , van Geloven A A W , van der Zaag E S , Wind J , Preckel B , Bossuyt P , Gouma D , Sprangers M , van Berge Henegouwen M I , Tanis P J , Buskens C J , van Lenthe I Picard , Bakker C , DeJong C H , van Dam R M , van der Peet D , van Zalingen E , Noordhuis A , Goei T H , van Tets W , deWit L , Clevers W , Bieleman A , Coenen L , Bonekamp E , van Abeelen J , van Iterson-de Jong D , Krombeen M 
Published: July 2014

Abstract

Background
Short-term advantages to laparoscopic surgery are well described. This study compared medium- to long-term outcomes of a randomized clinical trial comparing laparoscopic and open colonic resection for cancer.

Methods
The case notes of patients included in the LAFA study (perioperative strategy in colonic surgery; LAparoscopy and/or FAst track multimodal management versus standard care) were reviewed 2–5 years after randomization for incisional hernia, adhesional small bowel obstruction (SBO), overall survival, cancer recurrence and quality of life (QoL). The laparoscopic and open groups were compared irrespective of fast-track or standard perioperative care.

Results
Data on incisional hernias, SBO, survival and recurrence were available for 399 of 400 patients: 208 laparoscopic and 191 open resections. These outcomes were corrected for duration of follow-up. Median follow-up was 3·4 (i.q.r. 2·6–4·4) years. Multivariable regression analysis showed that open resection was a risk factor for incisional hernia (odds ratio (OR) 2·44, 95 per cent confidence interval (c.i.) 1·12 to 5·26; P = 0·022) and SBO (OR 3·70, 1·07 to 12·50; P = 0·039). There were no differences in overall survival (hazard ratio 1·10, 95 per cent c.i. 0·67 to 1·80; P = 0·730) or in cumulative incidence of recurrence (P = 0·514) between the laparoscopic and open groups. There were no measured differences in QoL in 281 respondents (P &gt; 0·350 for all scales).

Conclusion
Laparoscopic colonic surgery led to fewer incisional hernia and adhesional SBO events. Registration number: NTR222 (http://www.trialregister.nl).
Anticipated velocity based guidance strategy for wheeled mobile evader amidst stationary and moving obstacles in bounded environment
Authors: Kumar Amit , Ojha Aparajita 
Published: July 2014

AbstractThis paper is concerned with a class of pursuit‐evasion game problems amidst stationary and moving obstacles in a bounded environment. We concentrate on evader's strategy taking into account the following challenges: (i) pursuer and evader are nonholonomic wheeled mobile robots and the evader is slower than the pursuer; (ii) pursuer follows a proportional navigation law; and (iii) geometry of the environment is not known to the players, a priori. We propose an efficient evader‐centric anticipated velocity based guidance strategy. Pursuer's trajectory is anticipated at each step by the evader using quadratic polynomial interpolation. The aim of the evader is to escape interception with the pursuer for maximum possible time. To deal with static obstacles, a technique based on a well‐known tangent bug algorithm is presented. While dealing with dynamic obstacles, a recently introduced reciprocal orientation method is employed to avoid collision in situations when the dynamic obstacle also cooperates in the process. In case dynamic obstacles do not participate in the process of collision avoidance, a well‐known velocity obstacle method is employed for planning safe collision‐free paths. Efficiency of the proposed algorithms is analyzed with respect to the interception time and the distance traveled by the players. Copyright © 2014 John Wiley & Sons, Ltd.
Upper limb erythema nodosum: the first presentation of Crohn's disease
Authors: Faulkes R. E. 
Published: July 2014

Key Clinical MessageInflammatory bowel disease can present with extraintestinal features as the patient's only complaint. The erythema nodosum (EN) initially affected the upper limbs only, reminding us that signs do not always present in a classical fashion. The presence of EN should prompt the clinician to look for any underlying cause.
Application of In Situ Coating on a Two‐Compound System
Authors: Wendt Kristin , Petersen Sandra , Ulrich Joachim 
Published: July 2014

AbstractTo test the application of in situ coating as an alternative coating technology, pastilles drop‐formed from molten mixtures containing xylitol and isomalt were produced. The efficiency and usability of the classical nucleation techniques in this practical application could be demonstrated. Besides the influence of power ultrasound and seeding, the effect of a combination of both on nucleation at the shell of the drop‐formed melt mixtures was examined. Microscopic cross‐section pictures illustrate the impact on quality of the coating layer of drop‐formed pastilles.
Tuning a Single Ligand System to Stabilize Multiple Spin States of Manganese: A First Example of a Hydrazone‐Based Manganese(III) Spin‐Crossover Complex
Authors: Shongwe Musa S. , Al‐Barhi Kaltham S. , Mikuriya Masahiro , Adams Harry , Morris Michael J. , Bill Eckhard , Molloy Kieran C. 
Published: July 2014

AbstractA series of bis‐chelate pseudo‐octahedral mononuclear coordination complexes of manganese with the chromophore [MnN4O2]n+ (n=0, 1) have been generated in all three principal oxidation states of this transition‐metal center under ambient conditions by utilizing a readily tunable, versatile phenolic pyridylhydrazone ligand system (i.e., H2(3,5‐R1,R2)‐L; L=ligand). Strategic combinations of the nature and position of a variety of substituent groups afforded selective, spontaneous stabilization of multiple spin states of the manganese center, which, upon close crystallographic scrutiny, appears to be in part due to the occurrence or absence of hydrogen‐bonding interactions that involve the phenolate/phenolic oxygen atom. The divalent complexes are isolable in two forms, namely, molecular [MnII{H(3,5‐R1,R2)‐L}2] and ionic [MnII{H2(3,5‐R1,R2)‐L}{H(3,5‐R1,R2)‐L}]ClO4, with the latter complex converting easily into the former complex on deprotonation. Accessibility of the higher‐valent states is achievable only when the phenolate oxygen atom is sterically hindered from participation in hydrogen bonding. The [MnIII{H(3,5‐tBu2)‐L}2]ClO4 complex is the first example of a hydrazone‐based MnIII complex to exhibit spin crossover. Formation of the tetravalent complexes [MnIV{(3,5‐R1,R2)‐L}2] (R1=tBu, R2=H; R1=R2=tBu) necessitates base‐assisted abstraction of the hydrazinic proton.
Diastereoselective Nucleophilic Ring‐Opening Reactions of 2,6‐Diazasemibullvalenes for the Synthesis of Diverse Functionalized Δ1‐Bipyrroline Derivatives
Authors: Zhang Shaoguang , Zhan Ming , Zhang Wen‐Xiong , Xi Zhenfeng 
Published: July 2014

AbstractNucleophilic ring‐opening reactions of 2,6‐diazasemibullvalenes (NSBVs) were investigated. Different types of nucleophile (alcohols, phenols, thiols, carboxylic acids, water, enols, amines, indoles, metal‐halide salts, sodium azide, organozinc compounds, lithium alkynethiolate, and sulfoxonium ylides) were used to afford diverse functionalized Δ1‐bipyrroline derivatives in good yields with high regio‐ and diastereoselectivity. Most of the reactions featured milder conditions and higher reactivity relative to those for common aziridine derivatives, probably because of the rigid ring system and substitution patterns of NSBVs.
Identification of neuropeptide receptors expressed by melanin‐concentrating hormone neurons
Authors: Parks Gregory S. , Wang Lien , Wang Zhiwei , Civelli Olivier 
Published: July 2014

ABSTRACTMelanin‐concentrating hormone (MCH) is a 19‐amino‐acid cyclic neuropeptide that acts in rodents via the MCH receptor 1 (MCHR1) to regulate a wide variety of physiological functions. MCH is produced by a distinct population of neurons located in the lateral hypothalamus (LH) and zona incerta (ZI), but MCHR1 mRNA is widely expressed throughout the brain. The physiological responses and behaviors regulated by the MCH system have been investigated, but less is known about how MCH neurons are regulated. The effects of most classical neurotransmitters on MCH neurons have been studied, but those of most neuropeptides are poorly understood. To gain insight into how neuropeptides regulate the MCH system, we investigated which neuropeptide receptors are expressed by MCH neurons by using double in situ hybridization. In all, 20 receptors, selected based on either a suspected interaction with the MCH system or demonstrated high expression levels in the LH and ZI, were tested to determine whether they are expressed by MCH neurons. Overall, 11 neuropeptide receptors were found to exhibit significant colocalization with MCH neurons: nociceptin/orphanin FQ opioid receptor (NOP), MCHR1, both orexin receptors (ORX), somatostatin receptors 1 and 2 (SSTR1, SSTR2), kisspeptin recepotor (KissR1), neurotensin receptor 1 (NTSR1), neuropeptide S receptor (NPSR), cholecystokinin receptor A (CCKAR), and the κ‐opioid receptor (KOR). Among these receptors, six have never before been linked to the MCH system. Surprisingly, several receptors thought to regulate MCH neurons displayed minimal colocalization with MCH, suggesting that they may not directly regulate the MCH system. J. Comp. Neurol., 522:3817–3833, 2014. © 2014 Wiley Periodicals, Inc.
Review of spectral reflectance models for halftone prints: Principles, Calibration, and prediction accuracy
Authors: Hébert Mathieu , Hersch Roger D. 
Published: July 2014

AbstractReliable color reproduction can be achieved by establishing, using a model, the correspondence between the spectral reflectance of the printed surface and the amounts of deposited inks. In this article, we review the main models proposed in the literature, recall how each one is calibrated and compare their prediction accuracy for several print sets. The presented models are the Yule‐Nielsen modified spectral Neugebauer model, its cellular instance, the Clapper‐Yule model, its instance supporting low scattering, and the two‐by‐two halftone independent dot centering model. The Yule‐Nielsen and Clapper‐Yule based models are combined with ink spreading assessment methods that account for the interaction between light, inks, and paper. The prediction accuracy of the different models has been tested for several sets of printed colors on different supports, with different printing systems, different inks and different halftoning methods. These results show how the predictive performances and the model parameters vary according to the different printing setups. © 2014 Wiley Periodicals, Inc. Col Res Appl, 40, 383–397, 2015
A holistic model of the performance and the energy efficiency of hypervisors in a high‐performance computing environment
Authors: Guzek Mateusz , Varrette Sébastien , Plugaru Valentin , Pecero Johnatan E. , Bouvry Pascal 
Published: July 2014

SUMMARYVirtualization is emerging as the prominent approach to mutualise the energy consumed by a single server running multiple virtual machines instances. The efficient utilisation of virtualized servers and/or computing resources requires understanding of the overheads in energy consumption and the throughput especially on high‐demanding high‐performance computing (HPC) platforms. In this paper, a novel holistic model for the power of virtualized computing nodes is proposed. Moreover, we create and validate instances of the proposed model using concrete measures taken during a benchmarking process that reflects an HPC usage, that is, HPC challenge, IOZone and Bonnie++, conducted using two different hardware configurations on Grid'5000 platform, based on Intel and Advanced Micro Devices (AMD) processors and three widespread virtualization frameworks, namely, Xen, Kernel‐based virtual machine and VMware ESXi. The proposed holistic model of machine power takes into account the impact of utilisation metrics of the machine's components, as well as the employed application, virtualization and hardware. The model is further derived using tools such as multiple linear regressions or neural networks that prove its elasticity, applicability and accuracy. The purpose of the model is to enable the estimation of energy consumption of virtualized platforms, aiming to make possible the optimization, scheduling or accounting in such systems or their simulation. Copyright © 2014 John Wiley & Sons, Ltd.