bluuebunny/crossref_metadata_2025_split huggingface dataset:
MXene and Polymer Collision: Sparking the Future of High‐Performance Multifunctional Coatings
Authors: He Xiaoling , Cui Chengqiang , Chen Ying , Zhang Li , Sheng Xinxin , Xie Delong 
Published: August 2024

AbstractThe development of nanomaterials is crucial to upgrading of modern industry. MXene nanosheets have attracted significant attention due to their superb resistance to permeation, diverse surface chemical properties, impressive mechanical properties, and metal‐like electrical and thermal conductivity, etc., providing unique advantages in various technical fields. When MXene nanosheets are combined with polymers to form functional coatings, their applications span multiple fields, including anticorrosion, wear resistance, flame‐retardancy, electromagnetic interference (EMI) shielding, and de‐icing. This review, in conjunction with MXene's barrier property, lubricity, thermal stability, conductivity, and photothermal conversion property, discusses in detail the various applications of MXene‐based polymer coatings. Additionally, it examines the dispersion and interaction of MXene within polymer coatings and the role of functionalized MXene in polymers. Finally, based on the current research status and emerging needs, the development challenges and future research opportunities of MXene‐based polymer coatings in a targeted manner are discussed. This review aims to summarize the existing research results and put forward an objective and fair point of view, providing a constructive reference for upgrading modern nanofunctional polymer coatings.
Precise Regulation of Reactive Oxygen Species in Tumor Microenvironment for Alleviating Inhibitory Immunogenic Cell Death
Authors: Xu Zichuang , He Yuchu , Zhang Xuwu , Tu Wenkang , Li Xiaoling , Wang Dong , Yan Yaqian , Gao Jiajun , Wang Desong , Gao Dawei 
Published: August 2024

AbstractHigh level of reactive oxygen species (ROS) within the tumor microenvironment (TME) not only damage tumor cells but also diminish the efficacy of immunogenic cell death (ICD) and the activity of tumor‐infiltrating T lymphocytes, thereby limiting the effectiveness of immunotherapy. Therefore, precise modulation of ROS level is crucial to effectively eliminate tumor cells and activate ICD‐induced immunotherapy. Here, an intelligent yolk shell nanoplatform (SPCCM) that features calcium carbonate shells capable of decomposing under acidic TME conditions, thereby releasing the natural antioxidant proanthocyanidins (PAs) and the photosensitizer Ce6 is designed. PAs scavenge ROS within tumors, extending the survival time of T lymphocytes, while Ce6, as an ICD inducer, generates high ROS concentrations upon laser irradiation, thus reaching the toxic threshold within tumor cells and inducing apoptosis. The resulting apoptotic cells serve as tumor‐associated antigens, promoting dendritic cells (DCs) maturation, and activating ICD. By effectively neutralizing ROS in the TME, PAs sustainably reduce ROS level, thereby enhancing DCs activation and restoring antitumor immune cell activity suppressed by ROS (resulting in an eightfold increase in DCs activation). This study demonstrates effective synergistic effects between photodynamic therapy and immunotherapy by precisely modulating ROS level.
Unraveling the Solution Aggregation Structures and Processing Resiliency of High‐Efficiency Organic Photovoltaic Blends
Authors: Gao Mengyuan , Sun Chunlong , Li Yiwen , Li Na , Jiang Hanqiu , He Chunyong , Chen Yu , Zhao Wenchao , Hou Jianhui , Ye Long 
Published: August 2024

AbstractThe solution aggregation structure of conjugated polymers is crucial to the morphology and resultant optoelectronic properties of organic electronics and is of considerable interest in the field. Precise characterizations of the solution aggregation structures of organic photovoltaic (OPV) blends and their temperature‐dependent variations remain challenging. In this work, the temperature‐dependent solution aggregation structures of three representative high‐efficiency OPV blends using small‐angle X‐ray/neutron scattering are systematically probed. Three cases of solution processing resiliency are elucidated in state‐of‐the‐art OPV blends. The exceptional processing resiliency of high‐efficiency PBQx‐TF blends can be attributed to the minimal changes in the multiscale solution aggregation structure at elevated temperatures. Importantly, a new parameter, the percentage of acceptors distributed within polymer aggregates (Ф), for the first time in OPV blend solution, establishes a direct correlation between Ф and performance is quantified. The device performance is well correlated with the Kuhn length of the cylinder related to polymer aggregates L1 at the small scale and the Ф at the large scale. Optimal device performance is achieved with L1 at ≈30 nm and Ф within the range of 60 ± 5%. This study represents a significant advancement in the aggregation structure research of organic electronics.
Viruses and Non‐Woven Polymers: Surface Properties and Future Perspectives in Sampling for Wastewater‐Based Epidemiology
Authors: Ahmedullah Mayisha , Whiley Harriet , Fallowfield Howard , Köper Ingo 
Published: August 2024

AbstractEnvironmental disease monitoring initiatives such as wastewater‐based epidemiology can offer a unique perspective on the health status of a population. Such efforts are being increasingly utilized to guide public health initiatives and to aid in controlling the spread of infectious diseases. Key to these approaches is the sampling and identification of viruses, bacteria, and other pathogens. Advanced material technologies can be explored for the development of materials suitable for sampling, leading to the retention and detection of viruses. Here, how the surface interactions between viruses and adsorbent materials can inform the future development of effective, novel materials to aid in sampling viruses for wastewater‐based epidemiology are considered. This review provides a summary of the surface properties of viruses along with their physiochemical interactions with adsorbent materials at the solid‐water interface. Also discussed are the properties of non‐woven polymer membranes, a newer material technology being employed for the retention of viruses, with a focus on virus‐capture applications in aqueous environments.
Solid–Liquid Elastic Pendulum Triboelectric Nanogenerator Design for Application to Omnidirectional Blue Energy Harvesting
Authors: Zhang Xinyao , Su Yuxiang , Dong Xin , Wu Jinlin , Su Xiaonan , Dai Guanyu , Liu Anguo , Feng Wuwei , Zhao Keyang , Lei Bangjun , Li Zhenhua 
Published: August 2024

AbstractThe ocean is regarded as a significant resource for renewable energy development. The use of triboelectric nanogenerators (TENGs) provides an effective approach to capturing energy from low‐frequency, random, and disorganized water waves. In this paper, the solid–liquid elastic pendulum (SLEP)‐TENG is designed for omnidirectional blue energy harvesting applications. Differentiating from traditional designs, the proposed TENG has a simple, reliable, and durable flexible pendulum structure with a spherical shell and a solid counterweight at the bottom that can absorb the impact of ocean waves efficiently. The structure also has a hollow hexagonal space that allows it to generate a larger contact area when it is subjected to wave impacts from different directions. Under low‐speed lateral motion conditions (at frequencies below 0.83 Hz), its open‐circuit voltage VOC, short circuit current ISC, and power density Pm can reach up to 486.8 V, 16.9 µA, and 10.26 W m−3, respectively, which is sufficient to power more than 450 commercial light‐emitting diodes. By storing electrical power in small capacitors, the TENG can support small power‐consuming devices, e.g., thermometers and calculators. Therefore, the SLEP‐TENG has great potential for use in combination with Internet of Things devices to enable self‐powered sensing system construction in complex ocean areas.
Amplitude‐Phase Independently Encoding Space‐Division Multiplexed Wireless Communication Using Beamforming Reconfigurable Metasurfaces
Authors: Xiong Qi , Zhang Zuojun , Huang Cheng , Pu Mingbo , Luo Jun , Guo Yinghui , Ye Jia , Pan Wei , Ma Xiaoliang , Yan Lianshan , Luo Xiangang 
Published: August 2024

AbstractWireless communications utilizing reconfigurable metasurfaces have garnered significant attention due to their capability to transmit information without traditional radio‐frequency chains. Space‐division multiplexing techniques, in particular, can be utilized to improve their channel capacity. However, most of them are only implemented through either amplitude or phase encoding. Here, a space‐division multiplexed wireless communication system with amplitude‐phase independent encoding is proposed. By designing dual beams with varying power intensity ratios, dual channels that allow for independent amplitude modulation are established. The phase between the two channels can be independently modulated based on the pattern synthesis algorithm. By using the pattern nulling technique, independent modulation between amplitude and phase can be achieved in each channel. Compared to amplitude‐only modulation, amplitude‐phase modulation offers an additional degree of freedom for carrier wave modulation, which not only increases system capacity but also enhances physical layer security through directional modulation (DM) techniques. To demonstrate this approach, sixteen scattering beams are generated using a beamforming reconfigurable metasurface, and a dual‐channel 4 amplitude phase‐shift keying (4APSK) wireless communication system is experimentally realized. This work paves the way for establishing multiple channels, potentially applicable in multi‐user wireless communications.
Thermally‐Induced Reentrant Order‐Disorder‐Order Transitions in ALa9(GeO4)6O2 Apatites
Authors: Chufarov Alexander Yu. , Tyutyunnik Alexander P. , Tarakina Nadezda V. , Fortes A. Dominic , Melkozerova Marina A. , Enyashin Andrey N. , Lipina Olga A. , Baklanova Yana V. , Kiryakov Arseny N. , Surat Ludmila L. , Zubkov Vladimir G. 
Published: August 2024

AbstractOxyapatites A10(GeO4)6O2 (A – alkaline, rare‐earth elements) are considered promising materials for applications in solid‐state lighting and non‐contact thermometry. The temperature dynamics of the oxygen sublattice have a crucial influence on the luminescent properties of these optical hosts. Here, the structural evolution with temperature of germanates with the general formula ALa9(GeO4)6O2 (A – Li, Na, K, Rb) is investigated, using X‐ray and neutron powder diffraction methods. These compounds crystallize in space‐group P63/m. NPD experiments helped to determine the oxygen and alkaline metal positions. Thermally‐induced reentrant structural transitions relating to the oxygen in the apatite channel are discovered for the first time. In the example of Eu‐doped RbLa9(GeO4)6O2 and KLa9(GeO4)6O2, it is demonstrated that the luminescence of the Eu3+ ion is influenced by small changes in the crystal structure.
Dynamic Long‐Afterglow Materials with Ultralong Lifetime for Advanced Message Encryption
Authors: Tang Zhaorun , Zeng Jianwen , Zheng Yuewei , Guan Zhihao , Liu Xinghai 
Published: August 2024

AbstractUltralong afterglow materials has special optical properties and a broad application prospect in the field of information encryption. A single afterglow color largely limits the application of afterglow materials in the direction of advanced encryption, and materials with dynamic afterglow are more popular. However, most of the dynamic afterglow materials are doped with multiple chromophores, and these materials with a single chromophore are rarely reported and have low lifetimes. Herein, a series of dynamic afterglow materials with time‐dependent phosphorescence is obtained by a simple one‐step strategy, and the longest lifetime reached 1.39 s, the maximum PLQY reached 85.9%, and the naked‐eye duration reached 20 s, which is the best level reported so far. The dynamic afterglow phenomenon is attributed to the multiple phosphorescence emission centers of the guest molecule with different decay rates, which results in a dynamic shift of the phosphorescence color. It is demonstrated through a series of characterizations that the covalent bonding interaction between the guest molecule and the host boric acid largely inhibits the nonradiative leaps of the guest molecule and provides it with a rigid matrix environment. Crucially, the dynamic afterglow material has been successfully applied in the field of displays and advanced information encryption.
High‐Performance Orange Narrow Band Electroluminescent Material Based on Central Symmetry‐Arrangement of Two Fused Multiple Resonance Building Blocks
Authors: Lu Xueying , Cai XinLiang , Qu Yupei , Huang Tingting , Wei Jinbei , Song Xiaoxian , Wang Yue 
Published: August 2024

AbstractThe high‐performance multiple resonance thermally activated delayed fluorescence (MR‐TADF) materials with narrowband orange emission have considerable promise in automotive, signal indicators, and medical devices, due to their unique luminescent characteristic and potential applications in the organic electronic industry. However, the methodologies for constructing orange‐emitting materials with high color purity are relatively limited. In this contribution, an orange‐emitting MR‐TADF molecule (namely DBNN) is developed by employing a central symmetry‐arrangement of two fused MR‐building blocks to simultaneously realize spectral redshift and narrowband emission. DBNN exhibits intense orange emission with a narrow full width at half maximum (FWHM) of 28 nm (0.10 eV) and a high photoluminescence quantum yield (ΦPL) of 94%. By utilizing a novel exciplex host and a phosphorescent sensitizer to harvest excitons, the optimized DBNN‐based device demonstrates bright orange electroluminescence with a peak at 588 nm, high maximum external quantum efficiency (EQE) of 32.1% and small FWHM of 39 nm (0.14 eV). Additionally, the device achieves ultrahigh brightness exceeding 145 000 cd m−2 and low efficiency roll‐off, maintaining EQEs of 28.3% and 23.3% at luminescence of 1000 and 10 000 cd m−2, respectively.
Synthesis of Dithiocarbamate‐Functionalized Aliphatic Sulfonyl Fluoride via a One‐Pot Three‐Component Reaction
Authors: Mohamedy Heba H. , Fayad Eman , Katouah Hanadi A. , Qin Hua‐Li 
Published: August 2024

AbstractAn eco‐friendly and efficient method was developed for synthesizing a novel class of aliphatic sulfonyl fluorides in a catalyst‐free one‐pot reaction. The new approach offers a streamlined synthesis for N‐(Substituted)‐2‐(fluorosulfonyl) ethyl carbamodithioates by combining amines, carbon disulfide, with ethenesulfonyl fluoride. The synthesized compounds were obtained in good yields under mild conditions, making this reaction a valuable tool for exploring new chemical transformations.
Maternal rejection but not protectiveness predicts juvenile Japanese macaque behavior without direct maternal influence
Authors: Kuběnová Barbora , MacIntosh Andrew J. J. 
Published: August 2024

AbstractPrimates show large interindividual variability in the character and quantity of interactions between mothers and their immature offspring. Multiple studies have documented associations between maternal behavior and the occurrence or frequency of certain behaviors among offspring, but it remains unclear whether and how early maternal interactions generally affect behavioral development in offspring. We followed two wild groups of Japanese macaques on Yakushima island and investigated the relationship between maternal behavior and several types of behavior performed by 35 juvenile offspring. We further asked if the impact of maternal behavior on juvenile behavior persists regardless of the distance between mother and offspring, testing whether the influence extends beyond cases when the mother is nearby. We found that juveniles whose mothers frequently rejected them approached and played with others more often, independent of their mother's presence. Juveniles of more protective mothers were in proximity to fewer other individuals and played less, but only if their mothers were nearby. Maternal rejection appears to exert a generalized effect on offspring behavior that endures when mothers are absent. In contrast, effects of maternal protectiveness may be temporary and/or reflect direct maternal influences, such as active intervention in offspring interactions, or effects of the mother's own social relationships on offspring interactions. Our results suggest that understanding how maternal behavior affects offspring development requires paying attention to the context of juvenile behavior, including the mother's distance from her offspring.
Tetrapodal Hole‐Collecting Monolayer Materials Based on Saddle‐Like Cyclooctatetraene Core for Inverted Perovskite Solar Cells
Authors: Truong Minh Anh , Ueberricke Lucas , Funasaki Tsukasa , Adachi Yuta , Hira Shota , Hu Shuaifeng , Yamada Takumi , Sekiguchi Naomu , Nakamura Tomoya , Murdey Richard , Iikubo Satoshi , Kanemitsu Yoshihiko , Wakamiya Atsushi 
Published: August 2024

AbstractHole‐collecting monolayers have greatly advanced the development of positive‐intrinsic‐negative perovskite solar cells (p‐i‐n PSCs). To date, however, most of the anchoring groups in the reported monolayer materials are designed to bind to the transparent conductive oxide (TCO) surface, resulting in less availability for other functions such as tuning the wettability of the monolayer surface. In this work, we developed two anchorable molecules, 4PATTI‐C3 and 4PATTI‐C4, by employing a saddle‐like indole‐fused cyclooctatetraene as a π‐core with four phosphonic acid anchoring groups linked through propyl or butyl chains. Both molecules form monolayers on TCO substrates. Thanks to the saddle shape of a cyclooctatetraene skeleton, two of the four phosphonic acid anchoring groups were found to point upward, resulting in hydrophilic surfaces. Compared to the devices using 4PATTI‐C4 as the hole‐collecting monolayer, 4PATTI‐C3‐based devices exhibit a faster hole‐collection process, leading to higher power conversion efficiencies of up to 21.7 % and 21.4 % for a mini‐cell (0.1 cm2) and a mini‐module (1.62 cm2), respectively, together with good operational stability. This work represents how structural modification of multipodal molecules could substantially modulate the functions of the hole‐collecting monolayers after being adsorbed onto TCO substrates.
A Targeted Click‐to‐Release Activation of the Last‐Resort Antibiotic Colistin Reduces its Renal Cell Toxicity
Authors: Charoenpattarapreeda Jiraborrirak , Tegge Werner , Xu Chunfa , Harmrolfs Kirsten , Hinkelmann Bettina , Wullenkord Hannah , Hotop Sven‐Kevin , Beutling Ulrike , Rox Katharina , Brönstrup Mark 
Published: August 2024

AbstractThe use of highly potent but very toxic antibiotics such as colistin has become inevitable due to the rise of antimicrobial resistance. We aimed for a chemically‐triggered, controlled release of colistin at the infection site to lower its systemic toxicity by harnessing the power of click‐to‐release reactions. Kinetic experiments with nine tetrazines and three dienophiles demonstrated a fast release via an inverse‐electron‐demand Diels–Alder reaction between trans‐cyclooctene (TCO) and the amine‐functionalised tetrazine Tz7. The antibiotic activity of colistin against Escherichia coli was masked by TCO units, but restored upon reaction with d‐Ubi−Tz, a tetrazine functionalised with the bacterial binding peptide d‐Ubi29–41. While standard TCO did not improve toxicity against human proximal tubular kidney HK‐2 cells, the installation of an aspartic acid‐modified TCO masking group reduced the overall charge of the peptide and entry to the kidney cells, thereby dramatically lowering its toxicity. The analog Col−(TCO‐Asp)1 had favourable pharmacokinetic properties in mice and was successfully activated locally in the lung by d‐Ubi−Tz in an in vivo infection model, whereas it remained inactive and non‐harmful without the chemical trigger. This study constitutes the first example of a systemically acting two‐component antibiotic with improved drug tolerability.
Synergistic anticancer effect of polymersome‐encapsulated curcumin and cytarabine: A spectroscopic and theoretical approach
Authors: Das Debashree , Bhattacharya Sampurna , Ganguly Sreshtha , Sur Runa , Sen Kamalika 
Published: August 2024

AbstractCytarabine, also known as cytosine arabinoside is an anticancer drug, and it is widely used to treat acute myeloid leukemia (AML). But, clinical efficacy of highly hydrophilic cytarabine is often limited due to its rapid degradation and high biodistribution. Hence, this study aims to enhance the anticancer effect of cytarabine with the help of a naturally occurring polyphenol, curcumin. The interaction between cytarabine and curcumin was established by different spectroscopic techniques like UV–Visible, fluorescence, and Fourier transform infrared (FT‐IR). Molecular interactions were also studied using isothermal calorimetric titrations (ITC) followed by theoretical docking. The involvement of the amine group of cytarabine with the interaction of curcumin has been supported by FT‐IR and docking study. However, the major challenge with curcumin is that, in spite of its several medicinal benefits, poor solubility and bioavailability restricts its potential clinical applications. Hence, polymersome‐encapsulated curcumin (PEC) was prepared for the intravenous application. A two‐fold decrease in IC50 value of cytarabine against HeLa cell line was found in presence of encapsulated curcumin. This was justified on the basis of observed reactive oxygen species enhancement in serum in presence of cytarabine and PEC together, determined using absorption spectroscopy. The enhanced affinity of cytarabine toward DNA‐curcumin complex as compared to free DNA, supported by theoretical study, also validates the increased cytotoxicity of cytarabine in presence of PEC.
Toll‐Like Receptor 8 is Expressed in Monocytes in Contrast to Plasmacytoid Dendritic Cells and Mediates Aberrant Interleukin‐10 Responses in Patients With Systemic Sclerosis
Authors: Ehlers Christine , Thiele Thea , Biermann Hannah , Traidl Stephan , Bruns Luzia , Ziegler Annett , Schefzyk Matthias , Bartsch Lea M. , Kalinke Ulrich , Witte Torsten , Graalmann Theresa 
Published: August 2024

ObjectiveSystemic sclerosis (SSc) is a severe rheumatic disease causing fibrotic tissue rearrangement. Aberrant toll‐like receptor (TLR) 8 transcripts in plasmacytoid dendritic cells (pDCs) were recently linked to SSc pathogenesis, which is at least partially mediated by increased type I interferon (IFN‐I) responses. Here, we addressed the functional role of TLR8 signaling in different immune cell subsets of patients with SSc.MethodsMonocytes, conventional dendritic cells (cDCs), and pDCs from the blood and skin of patients with SSc were analyzed for TLR8 protein expression. To assess TLR function, cytokine responses upon TLR7 and TLR8 stimulation were studied. To identify relevant alterations specific for patients with SSc (n = 16), patients with primary Sjögren disease (pSS; n = 10) and healthy controls (HCs; n = 13) were included into the study.ResultsIn all individuals, TLR8 was expressed in monocytes and cDCs but not in pDCs. The TLR8 expression levels were overall similar in patients with SSc and pSS and HCs. Additionally, in all study participants, TLR8 stimulation of pDCs did not induce IFN‐I expression. In contrast, monocytes from patients with SSc revealed increased interleukin (IL)‐10 responses upon TLR8 (patients with SSc vs HCs, P = 0.0126) and TLR7/8 stimulation (patients with SSc vs HCs, P = 0.0170).ConclusionTLR8 protein is not expressed in pDCs of patients with SSc. Accordingly, they do not respond to TLR8 stimulation. In contrast, monocytes of patients with SSc respond to TLR8 stimulation with increased IL‐10 responses. Therefore, TLR8 signaling in monocytes participates in SSc pathogenesis by conferring aberrant IL‐10 expression.image