bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sincronías y sinergias animadas: La visión de la industria de la animación de Pixar y Ghibli
Authors: Montero Plata Laura , Pérez-Guerrero Ana María 
Published: May 2015

<p>Pixar y Ghibli, dos de los estudios más internacionalmente de la industria de la animación, han mantenido una estrecha relación a lo largo de sus más de veinticinco años, que va más allá de los claros homenajes que el estudio estadounidense ha hecho a las películas de Hayao Miyazaki. Organización de exposiciones, doblajes de películas, apoyo en la distribución, documentales o clases magistrales, tanto desde Pixar a Ghibli como en el caso contrario, ponen en evidencia la relación tan prolífica y polifacética que han entablado los dos estudios de animación a lo largo de los años. Para exponer y detallar esta estrecha colaboración comercial, artística y personal, hemos invitado a las investigadoras Laura Montero Plata y Ana María Pérez Guerrero —autoras respectivamente de El mundo invisible de Hayao Miyazaki (2012) y Pixar, las claves del éxito (2013)—, a desgranar la correspondencia entre estos dos gigantes de la animación.</p>
El verdadero ataque de los titanes: la combinación ganadora internacional de Shingeki no Kyojin
Authors: Seva Victoria Carmen Lavinia 
Published: May 2015

<p>Tras años de silenciosa pero creciente mejora de la animación japonesa, emerge Ataque a los titanes, una serie televisiva de tales dimensiones, en su producción y sus planes de mercado, que es imposible ignorarla por parte del gran público occidental. Ataque a los Titanes representa un recordatorio internacional de que la animación es una técnica capaz de subyugar también al espectador adulto. En este caso, es también una prueba de los últimos avances artísticos y técnicos en el anime, desde un lenguaje muy personal. Su triunfo no debe tanto a su idónea receta inicial como a su impresionante impacto en los públicos, convirtiéndose en un fenómeno viral, que la industria nipona ha sabido retroalimentar con suficiente maestría, hasta convertirlo en un colosal fenómeno de 2013. El presente artículo ahondará, en primer lugar, en la concepción de la serie, haciendo énfasis en los factores que la hacen destacar dentro de las series anime y en competencia con obras de acción real; en un segundo punto, introduciremos los valores artísticos de su unicidad; y, finalmente, evaluaremos su repercusión a nivel nacional e internacional.</p>
Cuentos de viejos: los relatos de la memoria
Authors: Dematei Marcelo , Piaggio María Laura 
Published: May 2015

<p>Cuentos de Viejos es un documental colaborativo transmedia que incluye una serie de animación para TV, una plataforma web y proyectos escolares. Concebido por las productoras HIERROanimación (Bogotá) y Piaggiodematei (Barcelona), fue elegido Mejor Proyecto Transmedia en el MIFA-Festival de Annecy 2012. Ese mismo año comenzó a producirse, coproducido por la TV pública colombiana (RTVC-Señal Colombia). La serie fue estrenada en septiembre de 2013, y está en producción una tercera temporada. Recibió numerosas distinciones internacionales, y en 2014 estuvo presente en decenas de festivales incluyendo Annecy, Hiroshima, Anima Mundi, Dok Leipzig, DocDF y Animasivo. Fue merecedor de dos premios TAL (de la Red de TV pública latinoamericana), nominado al Prix Jeunesse International y el Japan Prize, y obtuvo el India Catalina a la Innovación (otorgado por la academia colombiana de TV). También ha sido galardonado en el Savannah Animation Festival (USA), Golden Kuker (Bulgaria) y Anima (Argentina). En el siguiente artículo, dos de sus principales artífices nos revelan los entresijos de este inusual modelo de éxito.</p>
Deformar a la Gorgona: la imagen animada como estrategia para documentar el horror
Authors: Hachero Hernández Bruno 
Published: May 2015

<p>¿Qué nuevas relaciones con lo real propone el documental animado? ¿Qué nuevas configuraciones de lo visible y lo pensable plantea? Estudiar las características del documental animado a la luz del límite representativo que supone el horror es una oportunidad para reflexionar sobre la propia ontología de la imagen animada en su relación con lo real. Este artículo parte de Vals con Bashir para analizar cómo la animación se erige como imagen intermediaria frente a la no-imagen del horror. La imagen animada, al igual que el escudo de Perseo, permite abordar la realidad desde una determinada desfiguración, una distancia que plantea nuevas miradas y nuevos interrogantes para el cine.</p>
Entrevista a Gerben Schermer, director del Holland Animation Film Festival
Authors: Álvarez Sarrat Sara 
Published: May 2015

<p>Gerben Schermer (Países Bajos, 1959) puso películas. Pero, como Schermer afirma, “esa en marcha el Holland Animation Film Festival junto al director de animación Gerrit van Dijk, en 1985. Schermer ha desarrollado una destacada carrera en la selección y programación para el HAFF, además de diseñar programas invitados para numerosos festivales internacionales. Ha sido miembro de organizaciones y consultor de organismos internacionales, y en la actualidad es miembro del comité asesor del Programa de Diseño del fondo para las industrias creativas. Schermer ha estado también involucrado en la producción de películas, y en 2010 produjo Clown’s Revolution, del artista visual chino Sun Xun, que trabajó como artista en residencia para el HAFF. En esta entrevista Gerben Schermer nos habla del perfil del Holland Animation Film Festival, su visión sobre la animación y otros muchos temas de interés para profesionales, estudiantes y aficionados a la animación.</p>
El realismo animado de Sang-ho Yeon
Authors: Gómez Gurpegui Carlos 
Published: May 2015

<p>Este artículo se centra en la figura del director de animación surcoreano Sang-ho Yeong. Con solo dos largometrajes en su haber, ha logrado que sean las primeras cintas animadas de Corea del Sur en proyectarse en Cannes o ganar con su segunda cinta en Sitges. Su obra, aún poco conocida en nuestro país, realiza un crudo retrato de la sociedad surcoreana del momento. En el presente artículo revisaremos las bases sobre las que se asienta el cine de Sang-ho Yeong, trazando una correspondencia entre su cine y el cine independiente de animación de su país, y cómo ha sabido aunar el realismo y la animación creando un sólido discurso social, focalizando el estudio en sus dos largometrajes dirigidos hasta la fecha: The King of Pigs (Dwae-ji-ui Wang, 2011) y The Fake (Saibi, 2013).</p>
Conociendo a Silly Walks Studio
Authors: Andrés López Rafa , Valls Ajo P. 
Published: May 2015

<p>Silly Walks Studio es un equipo de reciente creación formado por cuatro jóvenes artistas especializados en desarrollo visual y animación 2D. Este colectivo se creó en 2013 después de que sus miembros concluyesen sus estudios gracias a una Startup UPV, un programa de apoyo a jóvenes, de la cual estos cuatro egresados en Bellas Artes han sido los primeros beneficiarios en toda la Universitat Politècnica de València. Por su carácter multidisciplinar podemos encontrar en la trayectoria de Silly Walks trabajos de Motion Graphics, espots publicitarios, arte para videojuegos e incluso participaciones en películas. Hasta la fecha han compaginado el desarrollo de proyectos propios con trabajos comerciales de cierta envergadura, como la secuencia de animación para la película Pixel Theory (2013) o la imagen gráfica y audiovisual para la 5ª Edición del Máster en Animación de la UPV (2013-15). Asimismo, en el último año han trabajado como diseñadores visuales y como animadores para el sector de los videojuegos, uniendo fuerzas con el estudio Brave Zebra. En las siguientes líneas podremos conocer de primera mano a este colectivo y hacer un repaso por su corta pero intensa carrera en el mundo audiovisual animado.</p>
The impact of hepatitis C virus infection on early post-liver transplantation complications and early graft function in a single low-volume liver transplant center
Authors: Buivydienė Arida , Basytė Viktorija , Mašalaitė Laura , Stanislovaitytė Danguolė , Adomavičiūtė Jurgita , Valantinas Jonas 
Published: May 2015

Background. End-stage liver disease associated with hepatitis C virus (HCV) infection has become one of the leading indications for liver transplantation. The effect of HCV infection on patients and long-term graft survival after orthotopic liver transplantation is well known. The aim of this study was to evaluate the impact of HCV infection on early post-liver transplantation complications and early graft function.
Materials and methods. Between July 2005 and February 2015 60 cadaveric orthotopic liver transplantations were performed in 58 adult patients at the Vilnius University Hospital Santariškių Clinics. We retrospectively reviewed our low-volume liver transplant center experience. To evaluate the changes that occurred in HCV-positive and HCV-negative transplant recipients, the study population was divided into two groups according to their HCV status. Statistical analysis was performed using the Microsoft Excel and SPSS 20.0 program. Group differences and data reliability were determined by the Student’s t-test.
Results. For 21 patients (35%) the indication for liver transplantation was end-stage liver disease due to HCV infection and for 39 patients (65%) there was another (non-HCV infection) indication. Overall, 29 patients (48%) have developed early biliary and/or vascular complications after transplantation: vascular complications were observed in 17 patients (28%) and biliary complications were observed in 12 patients (20%). Early graft function was good or fair in 52 patients (87%), primary dysfunction was observed in 8 (13%) patients.
Conclusions. The incidence of early post-transplant complications and early graft dysfunction had no statistically significant difference according to the patient’s HCV status.
Contraction force versus action potential duration of cardiomyocytes: which methodology is more informative for selection of effective 1,4-dihydropyridine compounds in experimental research?
Authors: Barsys Vygantas , Garalienė Vida , Urbonas Gediminas 
Published: May 2015

Background. Identification of activity properties of new synthesized compounds is important to help choose the adequate research methodology. The goal of this experimental research was to determine the relationship between the chemical structure of 25 compounds of 1,4-dihydropyridine derivatives and their effects on the contraction force of guinea pig papillary muscles and the action potential (AP) duration.
Methods. AP recordings were obtained with standard microelectrodes that were made from borosilicate glass capillaries, filled with 2.5 M KCl and connected to the high-input impedance amplification system. 1.0 Hz stimulation frequency was used. The contraction of papillary muscles was recorded by using a force transducer. Both signals (inotropic response and AP) were digitised by an A/D converter and registered by a computer specialised program.
Results. The results have shown that most of 1,4-dihydropyridine derivatives possessed the negative inotropic action and had the negligible impact on the AP duration.
It was identified that 1,4-dihydropyridine compound OSI 9719 (2-propoxyethyl-4-difloemethoxyphenyl-2-methyl-5-nitro-1,4-dihydro­pyridine-3carbo­xylate) had a prolonged duration of AP and simultaneously increased the force of contraction (p
Patellofemoral joint biomechanics in the females with anterior knee pain applying full weight bearing kinematic MRI
Authors: Brazaitis Andrius , Tamošiūnas Algirdas , Tutkuvienė Janina 
Published: May 2015

Purpose. The aim of the study was to evaluate biomechanics of the patellofemoral joint using full weight bearing kinematic MRI. We postulated that females with unilateral PFP might have greater medial femoral rotation in comparrison to the contralateral knee, also greater lateral patella tilt and displacement.
Methods. Forty four females aged 20–40 years with unilateral PFP were included in the study. The kinematic MRI examination was performed with a 1.5 T MRI unit. Full-weight bearing was used. Sagittal and axial images of the patellofemoral joint were acquired with a transmit-receive surface body coil. The study parameters, i. e. bisect offset, patella tilt angle, medial femoral rotation, patellar rotation at 0, 10, 20, 30, 40, 50° of flexion, were measured for both knees.
Results. Statistically significant changes were confirmed for greater bisect offset at all angles of flexion. The patella tilt angle increased steadily throughout full extension, but there was no significant difference in the tilt angle at 50° flexion. Greater medial femoral rotation was observed at all degrees of flexion, while patellar rotation showed no difference.
Conclusions. Our study has confirmed the growing body of literature, theorizing that the primary cause of PFP pain is altered femur dynamics under relatively stable patella.
Gonadotropins and Growth Hormone Family Characterization in an Endangered Siluriform Species, Steindachneridion parahybae (Pimelodidae): Relationship With Annual Reproductive Cycle and Induced Spawning in Captivity
Authors: Honji Renato Massaaki , Caneppele Danilo , Pandolfi Matias , Lo Nostro Fabiana Laura , Moreira Renata Guimarães 
Published: May 2015

ABSTRACTThe aim of this study was to identify and characterize pituitary cells of Steindachneridion parahybae females in captivity, highlighting the possible relationship with reproductive disorders at this level, since this species shows oocyte final maturation, ovulation and spawning dysfunction in captivity. The localization and distribution of growth hormone (GH), prolactin (PRL), somatolactin (SL), β‐luteinizing hormone (β‐LH), and β‐follicle stimulating hormone (β‐FSH) immunoreactive (‐ir) cells in the adenohypophysis was studied by immunohistochemical and Western blot methods. In addition, cellular morphometric analyses and semi‐quantification of ir‐cells optical density (OD) during the annual reproductive cycle and after artificial induced spawning (AIS) were performed. Results showed that the distribution and general localization of pituitary cell types were similar to that of other teleost species. However, the morphometrical study of adenohypophysial cells showed differences along the reproductive cycle and following AIS. In general, females at the vitellogenic stage presented greater OD values for GH, PRL and SL than at other maturation stages (previtellogenic and regression stages), probably indicating an increased cellular activity during this stage. Conversely, β‐LH OD did not vary during the annual reproductive cycle. After AIS, β‐LH, SL and GH ir‐cells showed an increase in OD values suggesting a possible involvement on oocyte final maturation, ovulation and spawning or a feedback control on the brain‐pituitary‐gonads axis. Reproductive dysfunction in S. parahybae females in captivity may be due to alteration of the synthesis pathways of β‐LH. In addition, GH family of hormones could modulate associated mechanisms that influence the reproductive status in this species. Anat Rec, 298:1644–1658, 2015. © 2015 Wiley Periodicals, Inc.
Determinants of Hydroxychloroquine Blood Concentration Variations in Systemic Lupus Erythematosus
Authors: Jallouli M. , Galicier L. , Zahr N. , Aumaître O. , Francès C. , Le Guern V. , Lioté F. , Smail A. , Limal N. , Perard L. , Desmurs‐Clavel H. , Le Thi Huong D. , Asli B. , Kahn J.‐E. , Pourrat J. , Sailler L. , Ackermann F. , Papo T. , Sacré K. , Fain O. , Stirnemann J. , Cacoub P. , Leroux G. , Cohen‐Bittan J. , Sellam J. , Mariette X. , Blanchet B. , Hulot J. S. , Amoura Z. , Piette J. C. , Costedoat‐Chalumeau N. ,   the Plaquenil Lupus Systemic Study Group
Published: May 2015

ObjectiveBlood concentrations of hydroxychloroquine (HCQ) vary widely among patients with systemic lupus erythematosus (SLE). A pharmacokinetic/pharmacodynamic relationship has been found in different situations, and a very low blood concentration of HCQ is a simple marker of nonadherence to treatment. Therefore, interest in blood HCQ concentration measurement has increased, but little is known about factors that influence blood HCQ concentration variability. This study was undertaken to analyze determinants of blood HCQ concentrations.MethodsWe conducted a retrospective analysis of patient data, including data from the Plaquenil Lupus Systemic (PLUS) study, to determine the association of epidemiologic, clinical, and biologic factors with blood HCQ concentrations. Data for nonadherent patients (blood HCQ concentration <200 ng/ml) were excluded.ResultsTo examine homogeneous pharmacologic data, we restricted the analyses of the PLUS data to the 509 SLE patients receiving 400 mg/day. We found no association of ethnicity or smoking with blood HCQ concentrations and no pharmacokinetic drug–drug interaction with antacids or with inhibitors or inducers of cytochrome P450 enzymes. On multivariate analysis, high body mass index (P = 0.008), no treatment with corticosteroids (P = 0.04), increased time between the last tablet intake and measurement of blood HCQ concentrations (P = 0.017), low platelet count (P < 0.001), low neutrophil count (P < 0.001), and high estimated creatinine clearance (P < 0.001) were associated with low blood HCQ concentrations. In 22 SLE patients with chronic renal insufficiency (median serum creatinine clearance 52 ml/minute [range 23–58 ml/minute]) who received 400 mg/day HCQ, the median blood HCQ concentration was significantly higher than that in the 509 patients from the PLUS study (1,338 ng/ml [range 504–2,229 ng/ml] versus 917 ng/ml [range 208–3316 ng/ml]) (P < 0.001).ConclusionWe provide a comprehensive analysis of determinants of blood HCQ concentrations. Because this measurement is increasingly being used, these data might be useful for clinicians.
Prognostic characteristics of duodenal gastrointestinal stromal tumours
Authors: Zhang Q , Shou C-H , Yu J-R , Yang W-L , Liu X-S , Yu H , Gao Y , Shen Q-Y , Zhao Z-C 
Published: May 2015

AbstractBackgroundThis study evaluated the clinical characteristics, surgical procedures and prognosis of duodenal gastrointestinal stromal tumours (GISTs).MethodsPatients with a diagnosis of primary duodenal GIST treated between January 2000 and December 2012 were analysed. Patients with gastric and small intestinal GISTs were chosen as control groups according to the following parameters: age, tumour size, mitotic index and adjuvant imatinib therapy. Operative procedures for patients with duodenal GIST included pancreaticoduodenectomy or limited resection. Disease-free survival (DFS) was calculated using Kaplan–Meier analysis.ResultsSome 71 patients with duodenal, 71 with gastric and 70 with small intestinal GISTs were included in the study. DFS of patients with duodenal GIST was shorter than that of patients with gastric GIST (3-year DFS 84 versus 94 per cent; hazard ratio (HR) 3.67, 95 per cent c.i. 1.21 to 11.16; P = 0.014), but was similar to that of patients with small intestinal GIST (3-year DFS 84 versus 81 per cent; HR 0.75, 0.37 to 1.51; P = 0.491). Patients who underwent pancreaticoduodenectomy were older, and had larger tumours and a higher mitotic index than patients who had limited resection. The 3-year DFS was 93 per cent among patients who had limited resection compared with 64 per cent for those who underwent PD (HR 0.18, 0.06 to 0.59; P = 0.001).ConclusionThe prognosis of duodenal GISTs is similar to that of small intestinal GISTs.
Communicating Corporate Social Responsibility to Internal Stakeholders: Walking the Walk or Just Talking the Talk?
Authors: Brunton Margaret , Eweje Gabriel , Taskin Nazim 
Published: May 2015

AbstractAs organizations recognize the need to engage in CSR and sustainability initiatives, it is integral to success to communicate that they are doing so. However, the research focus is more often on communicating with external stakeholders to draw attention to corporate responsibility initiatives. Internal stakeholders as employees are not researched as often, despite their integral role in communicating the organization's CSR vision and sustainability as they interact with external stakeholders. In order to explore employee perceptions of CSR communication, a two‐phase mixed‐method study was undertaken, including semi‐structured interviews with 20 CSR managers in NZ organizations to provide content to inform an online questionnaire survey to seek feedback from employees in these same organizations. This paper contributes to research on internal stakeholders in revealing the influence of the perceived value congruence between managers and employees in influencing internal stakeholder perceptions of CSR and sustainability initiatives. The findings have implications for public policy, enhancing organizational communication, the need for authenticity and managerial recognition of their role in facilitating employee commitment to CSR initiatives. Copyright © 2015 John Wiley & Sons, Ltd and ERP Environment
Aggregation‐Prone Amyloid‐β⋅CuII Species Formed on the Millisecond Timescale under Mildly Acidic Conditions
Authors: Pedersen Jeppe T. , Borg Christian B. , Michaels Thomas C. T. , Knowles Tuomas P. J. , Faller Peter , Teilum Kaare , Hemmingsen Lars 
Published: May 2015

AbstractMetal ions and their interaction with the amyloid beta (Aβ) peptide might be key elements in the development of Alzheimer's disease. In this work the effect of CuII on the aggregation of Aβ is explored on a timescale from milliseconds to days, both at physiological pH and under mildly acidic conditions, by using stopped‐flow kinetic measurements (fluorescence and light‐scattering), 1H NMR relaxation and ThT fluorescence. A minimal reaction model that relates the initial CuII binding and Aβ folding with downstream aggregation is presented. We demonstrate that a highly aggregation prone Aβ⋅CuII species is formed on the sub‐second timescale at mildly acidic pH. This observation might be central to the molecular origin of the known detrimental effect of acidosis in Alzheimer's disease.
Adaptive model predictive control of autonomic distributed parallel computations with variable horizons and switching costs
Authors: Mencagli G. 
Published: May 2015

SummaryAutonomic computing is a paradigm for building systems capable of adapting their operation when external changes occur, such as workload variations, load surges and changes in the resource availability. The optimal configuration in terms of the number of computing resources assigned to each component must be automatically adjusted to the new environmental conditions. To accomplish the execution goals with the desired Quality of Service, decision‐making strategies should be in charge of selecting the best reconfigurations by taking into account metrics like performance, efficiency (avoiding wasting resources), number and frequency of reconfigurations, and their amplitude (performing minimal modifications of the current configuration). This paper presents a decision‐making strategy that merges the potential of Model Predictive Control with a cooperative optimization framework. After a description of our approach, we investigate the effect of different switching costs to model the resource allocation problem. We use a control method in which our proactive decision‐making strategy (designed to use future prediction horizons) is made adaptive itself by dynamically changing the horizon length on the basis of the prediction errors. Simulations have been used to exemplify our approach and to discuss the effectiveness of the variable‐horizon strategy in achieving the best trade‐offs between reconfiguration metrics. Copyright © 2015 John Wiley & Sons, Ltd.