bluuebunny/crossref_metadata_2025_split huggingface dataset:
The impact of awareness of terminal illness on quality of death and care decision making: a prospective nationwide survey of bereaved family members of advanced cancer patients
Authors: Ahn Eunmi , Shin Dong Wook , Choi Jin Young , Kang Jina , Kim Dae Kyun , Kim Hyesuk , Lee Eunil , Hwang Kwan Ok , Oh Bumjo , Cho BeLong 
Published: July 2013

AbstractObjectsWe aimed to assess whether awareness of a terminal illness can affect care decision making processes and the achievement of a good death in advanced cancer patients receiving palliative care services.MethodsAwareness of terminal illness at the time of palliative care service admission was assessed by the health care professionals during the routine initial comprehensive assessment process and was recorded in the national terminal cancer patient registry. A follow‐up nationwide bereavement survey was conducted, which contained questions regarding decision making processes and the Korean version of the Good Death Inventory.ResultsAmong the 345 patients included in the final analysis, the majority (68.4%) of the patients were aware of the terminal illness. Awareness of the terminal illness tended to reduce discordances in care decision making (adjusted odds ratio = 0.55; 95% CI: 0.29–1.07), and increased the patients' own decision making when there were discordances between patients and their families (adjusted odds ratio = 3.79; 95% CI: 1.31–10.94). The Good Death Inventory score was significantly higher among patients who were aware of their terminal illnesses compared with those who were not (5.04 vs. 4.80; p = 0.013) and especially in the domains of ‘control over the future’ (5.18 vs. 4.04; p < 0.001), ‘maintaining hope and pleasure’ (4.55 vs. 3.92; p = 0.002), and ‘unawareness of death’ (4.41 vs. 4.26; p = 0.024).ConclusionAwareness of the terminal illness had beneficial effect on the harmonious decision making, patient autonomy, and patient's quality of death. Disclosure of terminal illness should be encouraged. Copyright © 2013 John Wiley & Sons, Ltd.
Use of 1,5‐diaminonaphthalene to combine matrix‐assisted laser desorption/ionization in‐source decay fragmentation with hydrogen/deuterium exchange
Authors: Lemaire Pascale , Debois Delphine , Smargiasso Nicolas , Quinton Loïc , Gabelica Valérie , De Pauw Edwin A. 
Published: July 2013

RATIONALEIn‐Source Decay (ISD) in Matrix‐Assisted Laser Desorption/Ionization (MALDI) mass spectrometry is a fast and easy top‐down activation method. Our objective is to find a suitable matrix to locate the deuterons following in‐solution hydrogen/deuterium exchange (HDX). This matrix must circumvent the commonly encountered undesired back‐exchange reactions, in order to preserve the regioselective deuteration pattern.METHODSThe 1,5‐diaminonaphthalene (1,5‐DAN) matrix is known to be suitable for MALDI‐ISD fragmentation. MALDI Mass Spectrometry Imaging (MSI) was employed to compare 1,5‐DAN and other commonly used MALDI matrices with respect to the extent of back‐exchange and the uniformity of the H/D exchange profiles within the MALDI spots. We tested the back‐exchange on the highly sensitive amyloid‐beta peptide (1‐40), and proved the regioselectivity on ubiquitin and β‐endorphin.RESULTSMALDI‐MSI results show that 1,5‐DAN leads to the least back‐exchange over all the spot. MALDI‐ISD fragmentation combined with H/D exchange using 1,5‐DAN matrix was validated by localizing deuterons in native ubiquitin. Results agree with previous data obtained by Nuclear Magnetic Resonance (NMR) and Electron Transfer Dissociation (ETD). Moreover, 1,5‐DAN matrix was used to study the H/D exchange profile of the methanol‐induced helical structure of β‐endorphin, and the relative protection can be explained by the polarity of residues involved in hydrogen bond formation.CONCLUSIONSWe found that controlling crystallization is the most important parameter when combining H/D exchange with MALDI. The 1,5‐DAN matrix is characterized by a fast crystallization kinetics, and therefore gives robust and reliable H/D exchange profiles using MALDI‐ISD. Copyright © 2013 John Wiley & Sons, Ltd.
A SEM and non‐contact surface white light profilometry in vivo study of the effect of a crème containing CPP‐ACP and fluoride on young etched enamel
Authors: Baroni Chiara , Marchionni Silvia , Bazzocchi Maria Giulia , Cadenaro Milena , Nucci Cesare , Manton David J 
Published: July 2013

SummaryThe aim of this in vivo study was to evaluate the short and a longer term effect on enamel of the application of a crème containing 10% CPP‐ACP and 900 ppm fluoride, in orthodontically planned, high caries‐risk patients. Epoxy resin replicas of upper lateral incisors were obtained from polyvinyl siloxane (PVS) impressions, before and after etching. The right incisors were left untreated in order to control saliva remineralizing potential. The upper left surfaces were coated with a pea‐size amount of the crème. Replicas were obtained at 3 weeks and 6 months and analyzed by SEM and non‐contact surface white light profilometry. In the treated sample the profilometric roughness parameters at 3 weeks were statistically significantly lower than the control group values (p < 0.05). At 3 weeks SEM images of the enamel surface showed fewer irregularities. After 6 months, differences between test and control groups were not present on SEM images and profilometric values. CPP‐ACP and fluoride crème had positive in vivo effects on enamel surfaces. Significant differences in surface roughness existed after a 3‐week period of crème use. SCANNING 36:270–277, 2014. © 2013 Wiley Periodicals, Inc.
A secure authentication scheme for session initiation protocol by using ECC on the basis of the Tang and Liu scheme
Authors: Irshad Azeem , Sher Muhammad , Faisal Muhammad Shahzad , Ghani Anwer , Ul Hassan Mahmood , Ashraf Ch Shehzad 
Published: July 2013

ABSTRACTSession initiation protocol (SIP) provides the basis for establishing the voice over internet protocol sessions after authentication and exchanging signaling messages. SIP is one of the significant and extensively used protocols in the multimedia protocol stack. Since the RFC2617 was put forth, numerous schemes for SIP authentication have been presented to overcome the flaws. Recently, in 2012, Tang and Liu proposed SIP based authentication protocol and claimed for eliminating the threats in Arshad and Ikram protocol. However the scheme can be made more robust by making further improvements, as the former scheme may come under a threat by adversaries through impersonating a server, given that the user password is compromised. We have proposed an improved protocol for SIP authentication by using elliptic curve cryptography that encounters the previous threat with enhanced security. The analysis shows that proposed scheme is suitable for applications with higher security requirements. Copyright © 2013 John Wiley & Sons, Ltd.
An aggregated signature‐based fast RFID batch detection protocol
Authors: Li Chaoliang , Wang Guojun , Zheng Jin 
Published: July 2013

ABSTRACTThe wireless channels between tags and readers are not secure in Internet of Things. Before a reader processes packets from tags, the reader should detect the integrity of these packets. In existing research, these packets are detected by readers one by one. This process is time‐consuming and impractical under some real‐time scenarios. To decrease the detection time, we propose a fast radio‐frequency identification batch detection protocol that is more suitable to detect whether the packets are modified by adversaries. The analysis and experimental results show that the proposed protocol has the following good properties: (i) it can detect the integrity of packets very fast; (ii) it has better performance in computational cost and storage cost of tags and servers; (iii) it can provide security protection in an efficient way. Copyright © 2013 John Wiley & Sons, Ltd.
Tunable Assembly of Gold Nanoparticles on Nanopatterned Poly(ethylene glycol) Brushes
Authors: Onses M. Serdar , Nealey Paul F. 
Published: July 2013

AbstractThe organization of metallic nanoparticles (NPs) into ordered arrays on nanopatterned surfaces is an enabling process to fabricate devices and study the properties of the particles. Tailoring the interaction between NPs and nanopatterns is a necessity to gain a high level of control in this process. Here, nanopatterned poly(ethylene glycol) (PEG) brushes are presented as a platform for the organization of Au NPs on surfaces. The binding of citrate‐stabilized Au NPs to the PEG brushes depends on the size of the particles and molecular weight of the brushes: the density of NPs immobilized on the nanopatterns of PEG brushes increases with decreasing the diameter of the particles and increasing the chain length of the brushes. The key aspect of the process is to pattern PEG brushes with high resolution and chemical contrast to provide controllable and specific interaction between Au NPs and nanopatterns at a single particle resolution. The modulation of the number (0–4) of Au NPs (e.g., 30 nm) per patterned feature with a high level of accuracy and the generation of patterned heterostructures that consist of two different sizes (e.g., 40 and 20 nm) of particles constitute two examples showing the capabilities of the presented platform.
Students' conceptual change in electricity and magnetism using simulations: A comparison of cognitive perturbation and cognitive conflict
Authors: Dega Bekele Gashe , Kriek Jeanne , Mogese Temesgen Fereja 
Published: July 2013

AbstractThe purpose of this study was to investigate Ethiopian physics undergraduate students' conceptual change in the concepts of electric potential and energy (EPE) and electromagnetic induction (EMI). A quasi‐experimental design was used to study the effect of cognitive perturbation using physics interactive simulations (CPS) in relation to cognitive conflict using physics interactive simulations (CCS). Data were collected by using the modified Diagnostic Exam of Electricity and Magnetism (DEEM). ANCOVA was conducted on the scores of 45 students on the modified DEEM test to compare the effectiveness of the CCS and CPS. The results showed a significant difference between the two classes of the post‐test scores on the DEEM test, (1, 36) = 4.66, p = 0.04, partial eta squared = 0.12. Consequently, it was concluded that there is a statistically significant difference between CPS and CCS in changing students' alternative conceptions towards scientific conceptions favoring CPS. Medium practical difference between the two classes was estimated by the partial eta squared effect size. To characterize and compare improvement of the students' conceptual learning in both treatment classes, Hake's average normalized gain 〈g〉 from pre‐ to post‐scores were analyzed. It is suggested that in abstract conceptual areas of electricity and magnetism, in which most students have inappropriate and counterproductive responses, cognitive perturbation through interactive simulations is more effective than cognitive conflict through interactive simulations in facilitating conceptual change, and, thus, can improve classroom instruction in the area. Recommendations are also suggested for guiding future research in this area. © 2013 Wiley Periodicals, Inc. J Res Sci Teach
How do students in an innovative principle‐based mechanics course understand energy concepts?
Authors: Ding Lin , Chabay Ruth , Sherwood Bruce 
Published: July 2013

AbstractWe investigated students' conceptual learning of energy topics in an innovative college‐level introductory mechanics course, entitled Matter & Interactions (M&I) Modern Mechanics. This course differs from traditional curricula in that it emphasizes application of a small number of fundamental principles across various scales, involving microscopic atoms, macroscopic deformable objects, and large‐scale planetary systems. To best match the unique features of this course, a multiple‐choice energy assessment was developed. We followed the development framework and explicitly delineated test purpose, scope, and specifications to guide the design, implementation and evaluation of the energy assessment. Also, particular attention was given to: (1) categorizing content and cognition levels and (2) determining reasoning steps of each test item—aspects that often were not explicitly addressed in designing prior concept assessments. We implemented the energy assessment as a written test before and after course instruction with M&I students at two research universities. Interviews were also conducted to explore students' reasoning in applying energy concepts. Results showed that positive change in student conceptual understanding after course instruction was significant on the entire assessment, on individual items, and on individual test objectives. Subsequent interviews further revealed that after instruction students could properly apply the Energy Principle and perform qualitative analysis without using formula sheets. However, students still showed difficulty in dealing with systems involving deformable objects. This study exemplifies practical means of establishing and evaluating key assessment features, provides evidence for the effectiveness of a principle‐focused approach to physics learning, and offers useful implications for teaching energy topics. © 2013 Wiley Periodicals, Inc. J Res Sci Teach 9999: 1–26, 2013
Multiscale image‐based modeling and simulation of gas flow and particle transport in the human lungs
Authors: Lin Ching‐Long , Tawhai Merryn H. , Hoffman Eric A. 
Published: July 2013

Improved understanding of structure and function relationships in the human lungs in individuals and subpopulations is fundamentally important to the future of pulmonary medicine. Image‐based measures of the lungs can provide sensitive indicators of localized features, however to provide a better prediction of lung response to disease, treatment, and environment, it is desirable to integrate quantifiable regional features from imaging with associated value‐added high‐level modeling. With this objective in mind, recent advances in computational fluid dynamics (CFD) of the bronchial airways—from a single bifurcation symmetric model to a multiscale image‐based subject‐specific lung model—will be reviewed. The interaction of CFD models with local parenchymal tissue expansion—assessed by image registration—allows new understanding of the interplay between environment, hot spots where inhaled aerosols could accumulate, and inflammation. To bridge ventilation function with image‐derived central airway structure in CFD, an airway geometrical modeling method that spans from the model ‘entrance’ to the terminal bronchioles will be introduced. Finally, the effects of turbulent flows and CFD turbulence models on aerosol transport and deposition will be discussed. WIREs Syst Biol Med 2013, 5:643–655. doi: 10.1002/wsbm.1234This article is categorized under:

Analytical and Computational Methods > Computational Methods
Models of Systems Properties and Processes > Organ, Tissue, and Physiological Models
Varied Layer Topologies in Luminescent Zinc Coordination Polymers with Flexible Aromatic ortho‐Dicarboxylate and Dipyridyl Ligands
Authors: Murray Nathan H. , Farnum Gregory A. , LaDuca Robert L. 
Published: July 2013

AbstractHydrothermal synthesis has afforded four divalent zinc flexible‐arm aromatic ortho‐dicarboxylate coordination polymers containing dipyridyl coligands. According to X‐ray crystallography, all four show layered coordination polymer structures. Nevertheless there is significant ligand influence on the nature of zinc atom aggregation and overall topology. In both {[Zn2(hmph)2(dpa)2]·2H2O}n (1) (hmph = homophthalate, dpa = 4, 4′‐dipyridylamine), and {[Zn2(hmph)2(dpe)2](ClO4)2·H2dpe·4H2O}n (2) [dpe = bis(4‐pyridyl)ethane], large {Zn2(hmph)2} dimeric units are evident, along with an overall herringbone (6, 3) layer topology. The longer span of the dpe ligands results in larger incipient channels, which can accommodate protonated dpe dications and perchlorate counterions. In {[Zn2(hmph)2(3‐pna)]·H2O}n (3) (3‐pna = 3‐pyridylnicotinamide), {Zn2(OCO)2} anti‐syn bridged dimers and {Zn2(OCO)4} syn‐syn paddlewheel dimers coexist and are linked together by hmph and 3‐pna ligands into decorated (4, 4) grid coordination polymer layers. {[Zn(1, 2‐phda)(3‐pina)]·2H2O}n (4) (1, 2‐phda = 1, 2‐phenylenediacetate, 3‐pina = 3‐pyridylisonicotinamide) manifests an undulating (4, 4) grid structure with isolated zinc atoms; the “wavelength” of the layers measures over 40 Å. Luminescent properties of these materials are also reported.
An Oxygen/Chlorine Double‐Capped Praseodymium Tetramer Cluster Complex with Thiazole
Authors: Dannenbauer Nicole , Müller‐Buschbaum Klaus 
Published: July 2013

AbstractA tetramer cluster complex of the formula [Pr4Cl10(OH)2(thz)8(H2O)2] was prepared constituted by two edge sharing metal triangles coordinated by thiazole (thz) and chloride ligands bent together by opposing μ3‐hydroxide and chloride capping for both triangles. The tetramer is the first thiazole complex of a lanthanide ion and shows a previously unknown symmetric capping mode. It co‐crystallizes with an anhydrous dimeric complex of the formula [Pr2Cl6(thz)8] in equal amounts.
The New Homoleptic Tetracyanamidoaluminate LiBa2[Al(CN2)4]
Authors: Unverfehrt Leonid , Ströbele Markus , Meyer H.‐Jürgen 
Published: July 2013

AbstractThe new tetracyanamidoaluminate LiBa2[Al(CN2)4] was prepared by solid state metathesis reaction in a fused copper ampoule from a mixture of BaF2, AlF3, and Li2(CN2) at 550 °C. The crystal structure was solved and refined based on single‐crystal X‐ray diffraction data [P212121, Z = 4, a = 6.843(1) Å, b = 11.828(2) Å, c = 11.857(2) Å]. The compound belongs to the known formula type LiM2[Al(CN2)4] (M = Sr, Eu) containing the homoleptic [Al(CN2)4]5– ion. However, LiBa2[Al(CN2)4] forms a distinct crystal structure, containing a two‐dimensional [(NCN)2/2Li(NCN)2Al(NCN)2/2] network with four‐coordinate Li+ and Al3+ ions. Two crystallographically independent Ba2+ ions are situated in eightfold environment of terminal nitrogen atoms of cyanamide ions.
Groundwater Flow Modelling of Hindon-Yamuna Interfluve Region, Western Uttar Pradesh
Authors: Alam Fakhre , Umar Rashid 
Published: July 2013

Abstract:
The study area Hindon -Yamuna interfluve region is underlain by a thick pile of unconsolidated Quaternary alluvial deposits and host multiple aquifer system. Excessive pumping in the last few decades, mainly for irrigation, has resulted in a significant depletion of the aquifer. Therefore, proper groundwater management of Hindon-Yamuna interfluve region is necessary. For effective groundwater management of a basin it is essential that careful zone budget study should be carried out. Keeping this in view, groundwater flow modelling was attempted to simulate the behavior of flow system and evaluate zone budget. Visual MODFLOW, pro 4.1 is used in this study to simulate groundwater flow. The model simulates groundwater flow over an area of about 1345 km2 with a uniform grid size of 1000 m by 1000 m and contains three layers, 58 rows and 37 columns. The horizontal flows, seepage losses from unlined canals, recharge from rainfall and irrigation return flows were applied using different boundary packages available in Visual MODFLOW, pro 4.1. The river – aquifer interaction was simulated using the river boundary package. Simulated pumping rates of 500 m3/day, 1000 m3/day and 1500 m3/day were used in the pumping well package. The zone budget for the steady state condition of study area indicated that the total annual direct recharge is 416.10 MCM and the total annual groundwater draft through pumping is of the order of 416.63 MCM. Two scenarios were considered to predict aquifer system response under different conditions. Sensitivity analysis on model parameters was conducted to quantitatively evaluate the impact of varying model inputs. Based on the results obtained from the sensitivity analysis, it was found that the model is more sensitive to hydraulic conductivity and recharge parameter. Present study deals with importance of groundwater modelling for planning, design, implementation and management of groundwater resources.
A New Occurrence of Sapphirine-Spinel-Corundum-bearing Granulite from NE of Jagtiyal, Eastern Dharwar Craton, Andhra Pradesh
Authors: Prakash D. , Singh P. Chandra , Hokada T. 
Published: July 2013

Abstract:
We report a new occurrence of sapphirine-spinel-corundum bearing granulites enclosed in granitic gneisses near Jagtiyal in the Eastern Dharwar Craton (EDC). These granulites are very important in deciphering the prehistory of the thermal peak of metamorphism due to the presence of refractory phases. The appearance of sapphirine is related to the following reactions: (a) Spl1 + Crd1 = Spr1 (2:2:1) (b) Phl (in Bt1) + Crn1 = East (in Bt2) + Spr2 (7:9:3) + Crd2 (c) Bt2 + Crd1 +Crn1 = Spr2 (7:9:3) + Kfs + H2O (d) Crd1 + Spl1 + Crn1 = Spr2 (7:9:3). The P–T evolution of these sapphirine granulites has been constrained through the use of THERMOCALC program. Temperature of formation of sapphirine-spinel assemblages is high, around 800 °C, and pressure ranges from 5-7 kbars, suggesting that sapphirine formation took place during decompression stage.