bluuebunny/crossref_metadata_2025_split huggingface dataset:
Double‐edged stars: Michelin stars, reactivity, and restaurant exits in New York City
Authors: Sands Daniel B. 
Published: August 2024

AbstractResearch SummaryThis article develops a theoretical framework to explicate how third parties, who are not transactionally involved in a given exchange relationship, can promote or impede the creation and capture of value by influencing market actor beliefs and behaviors. I investigate these issues empirically through an abductive mixed‐method case study of the Michelin Guide's entry into New York City. An examination of two decades of the openings and closings of New York City's elite restaurants indicates that receiving a Michelin star corresponded to an increased likelihood of restaurant exit. Michelin stars appear to have fostered disruptions at recipients' upstream and downstream interfaces, which inhibited their ability to capture value. This ultimately underscores how value network reactivity to third‐party evaluations may lead to unintended consequences for firms.Managerial SummaryThis article explains how third‐party evaluators' reviews, ratings, and rankings can promote or impede the creation and capture of value. This occurs because third‐party evaluations engender reactions by those being evaluated, as well as reactions by other market actors such as competitors and exchange partners. I study these issues within the context of the Michelin Guide's entry into New York City, and my findings indicate that restaurants that received a Michelin star were more likely to close in subsequent years. Evidence suggests that intensified bargaining problems with landlords, suppliers, and employees, along with heightened consumer expectations, created new challenges for these Michelin‐starred restaurants, which ultimately made it more difficult for them to stay in business.
Empirische Untersuchung zum Status quo der externen Unternehmensberichterstattung über digitale Transformation und Würdigung vor dem Hintergrund der Anforderungen potenzieller Stakeholder
Authors: Pelster Clemens 
Published: August 2024

ZusammenfassungUm ein Berichtskonzept zur entscheidungsnützlichen externen Berichterstattung über digitale Transformation zu entwickeln, soll im Verlauf der vorliegenden Arbeit die folgende Leitfrage beantwortet werden: Wer sollte wem, wozu, wo, wann, was und wie zur digitalen Transformation berichten? In Kapitel 3 wurden zur Beantwortung dieser Fragen zunächst die Anforderungen potenzieller Adressaten einer solchen Berichterstattung erhoben. Mögliche Erwartungen an eine Berichterstattung zur digitalen Transformation innerhalb des (Konzern-)Lageberichts wurden in Kapitel 4 formuliert. Gegenstand des vorliegenden Kapitels ist die Praxis der externen Berichterstattung über digitale Transformation. Es ist das Ziel, auf Basis des Stands der Forschung und einer eigenen Untersuchung ausgewählter Konzernlageberichte den Status quo der externen Berichterstattung über digitale Transformation zu erheben. Anhand der Ergebnisse soll zudem gewürdigt werden, inwieweit die zuvor erhobenen Anforderungen potenzieller Adressaten bereits erfüllt werden (können). Darüber hinaus sollen Verbesserungspotenziale und best practices identifiziert werden, um sie in dem nachfolgend entwickelten Berichtskonzept zu berücksichtigen. In Abschnitt 5.2 wird zunächst der Stand der Forschung zur externen Berichterstattung über digitale Transformation dargelegt und die eigene Untersuchung von den bestehenden abgegrenzt. Im Anschluss werden die Konzernlageberichte 2019 und 2021 ausgewählter Unternehmen im Hinblick auf Angaben zur digitalen Transformation analysiert (Abschnitt 5.3 und 5.4). Die Studie ist die erste, in welcher unter Berücksichtigung der regulatorischen Vorgaben eines Berichtsinstruments sowohl die Verortung von digitalisierungsbezogenen Informationen innerhalb der Berichtsbestandteile als auch deren Inhalte sowie die Art ihrer Darstellung analysiert und zugleich die Anforderungen potenzieller Stakeholder für eine Würdigung berücksichtigt werden. Zu Beginn der zunächst folgenden Beschreibung des Forschungsdesigns, werden der Forschungsgegenstand erläutert und die Forschungsfragen aus der zuvor genannten Leitfrage zur Entwicklung des Berichtskonzepts abgeleitet (Abschnitt 5.3.1). Nach der Beschreibung der Datenbasis (Abschnitt 5.3.2) wird die verwendete Methode der integrativen Inhaltsanalyse sowie der Ablauf der Analyse beschrieben und das Kategoriensystem erläutert (Abschnitt 5.3.3). Sodann folgt eine Darstellung des Status quo der externen Berichterstattung über digitale Transformation als Ergebnis der Analyse (Abschnitt 5.4). Abschließend werden die Ergebnisse vor dem Hintergrund der Anforderungen potenzieller Stakeholder zusammenfassend gewürdigt und ein Zwischenfazit gezogen (Abschnitt 5.5).
Celestial holography revisited. Part II. Correlators and Källén-Lehmann
Authors: Iacobacci Lorenzo , Sleight Charlotte , Taronna Massimo 
Published: August 2024

Abstract
In this work we continue the investigation of the extrapolate dictionary for celestial holography recently proposed in [1], at both the perturbative and non-perturbative level. Focusing on scalar field theories, we give a complete set of Feynman rules for extrapolate celestial correlation functions and their radial reduction in the hyperbolic slicing of Minkowski space. We prove to all orders in perturbation theory that celestial correlators can be rewritten in terms of corresponding Witten diagrams in EAdS which, in the hyperbolic slicing of Minkowski space, follows from the fact that the same is true in dS space. We then initiate the study of non-perturbative properties of celestial correlators, deriving the radial reduction of the Källén-Lehmann spectral representation of the exact Minkowski two-point function. We discuss the analytic properties of the radially reduced spectral function, which is a meromorphic function of the spectral parameter, and highlight a connection with the Watson-Sommerfeld transform.
GP100 expression is variable in intensity in melanoma
Authors: Mann Jacqueline E. , Hasson Nitzan , Su David G. , Adeniran Adebowale J. , Smalley Keiran S. M. , Djureinovic Dijana , Jilaveanu Lucia B. , Schoenfeld David A. , Kluger Harriet M. 
Published: August 2024

AbstractDrugs or cellular products that bind to gp100 are being investigated for treatment of cutaneous melanoma. The relative specificity of gp100 expression in melanocytes makes it an attractive target to harness for therapeutic intent. For example, Tebentafusp, a bispecific gp100 peptide-HLA-directed CD3 T cell engager, has generated significant enthusiasm in recent years due to its success in improving outcomes for uveal melanoma and is being studied in cutaneous melanoma. However, the extent and intensity of gp100 expression in advanced cutaneous melanoma has not been well studied. Here, we interrogated a large cohort of primary and metastatic melanomas for gp100 expression by immunohistochemistry. Expression in metastatic samples was globally higher and almost uniformly positive, however the degree of intensity was variable. Using a quantitative immunofluorescence method, we confirmed the variability in expression. As gp100-binding drugs are assessed in clinical trials, the association between activity of the drugs and the level of gp100 expression should be studied in order to potentially improve patient selection.
Predictive value of the single most suspicious ultrasound feature in subcentimeter thyroid nodules: a retrospective observational cohort study
Authors: Huang Peiying , Han Lili , Shi Xiulin , Xiao Fangsen , Shen Qingbao , Li Xuejun , Zhang Fuxing 
Published: August 2024

Abstract
Purpose
Proper management of subcentimeter thyroid nodules remains challenging for both clinicians and patients. Conducting extensive sonographic research using a safe and inexpensive tool for identifying thyroid nodules is necessary. The aim of this study was to identify whether having the highest-risk ultrasound (US) characteristic suggests that US-guided fine-needle aspiration (FNA) biopsy of subcentimeter nodules is more appropriate for the identification of malignancy than active surveillance (AS) or surgery.

Methods
The data of patients with highly suspicious subcentimeter thyroid nodules and US characteristic data who underwent surgery were retrospectively examined.

Results
Among a total of 556 subcentimeter nodules, 223 (40.1%) were benign, and 333 (59.9%) were malignant, with a mean maximal nodule size of 8.1 mm. In addition to age younger than 45 years, several US features were significantly associated with malignancy: irregular margins, the presence of microcalcifications, and taller-than-wide shapes (P < 0.001). Multivariate analysis also revealed that a taller-than-wide shape (OR = 8.988, P = 0.0015) was an independent factor associated with malignancy in subcentimeter thyroid nodules. The diagnostic performance of preoperative FNA was classified as a malignancy, with a sensitivity of 98.4%, specificity of 100%, positive predictive value of 100%, and negative predictive value of 76.9%.

Conclusions
This is one of the few reports based on actual data of the most suspicious US features in subcentimeter thyroid nodules. A taller-than-wide shape US feature is most significantly associated with malignancy. FNA is a simple, accurate, and reliable preoperative method for diagnosing malignant subcentimeter thyroid nodules with highly suspicious US characteristics. AS was less appropriate than FNA for subcentimeter nodules with a taller-than-wide shape, especially in patients ≤ 45 years of age.
Large language models in healthcare: from a systematic review on medical examinations to a comparative analysis on fundamentals of robotic surgery online test
Authors: Moglia Andrea , Georgiou Konstantinos , Cerveri Pietro , Mainardi Luca , Satava Richard M. , Cuschieri Alfred 
Published: August 2024

AbstractLarge language models (LLMs) have the intrinsic potential to acquire medical knowledge. Several studies assessing LLMs on medical examinations have been published. However, there is no reported evidence on tests related to robot-assisted surgery. The aims of this study were to perform the first systematic review of LLMs on medical examinations and to establish whether ChatGPT, GPT-4, and Bard can pass the Fundamentals of Robotic Surgery (FRS) didactic test. A literature search was performed on PubMed, Web of Science, Scopus, and arXiv following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) approach. A total of 45 studies were analyzed. GPT-4 passed several national qualifying examinations with questions in English, Chinese, and Japanese using zero-shot and few-shot learning. Med-PaLM 2 obtained similar scores on the United States Medical Licensing Examination with more refined prompt engineering techniques. Five different 2023 releases of ChatGPT, one of GPT-4, and one of Bard were tested on FRS. Seven attempts were performed with each release. The pass score was 79.5%. ChatGPT achieved a mean score of 64.6%, 65.6%, 75.0%, 78.9%, and 72.7% respectively from the first to the fifth tested release on FRS vs 91.5% of GPT-4 and 79.5% of Bard. GPT-4 outperformed ChatGPT and Bard in all corresponding attempts with a statistically significant difference for ChatGPT (p < 0.001), but not Bard (p = 0.002). Our findings agree with other studies included in this systematic review. We highlighted the potential and challenges of LLMs to transform the education of healthcare professionals in the different stages of learning, by assisting teachers in the preparation of teaching contents, and trainees in the acquisition of knowledge, up to becoming an assessment framework of leaners.
Fine-scale deep learning model for time series forecasting
Authors: Chen Yuwei , Jia Wenjing , Wu Qiang 
Published: August 2024

AbstractTime series data, characterized by large volumes and wide-ranging applications, requires accurate predictions of future values based on historical data. Recent advancements in deep learning models, particularly in the field of time series forecasting, have shown promising results by leveraging neural networks to capture complex patterns and dependencies. However, existing models often overlook the influence of short-term cyclical patterns in the time series, leading to a lag in capturing changes and accurately tracking fluctuations in forecast data. To overcome this limitation, this paper introduces a new method that utilizes an interpolation technique to create a fine-scaled representation of the cyclical pattern, thereby alleviating the impact of the irregularity in the cyclical component and hence enhancing prediction accuracy. The proposed method is presented along with evaluation metrics and loss functions suitable for time series forecasting. Experiment results on benchmark datasets demonstrate the effectiveness of the proposed approach in effectively capturing cyclical patterns and improving prediction accuracy.
Routine Data Analysis of HIV Pre-Exposure Prophylaxis Use and Rates of Sexually Transmitted Infections Since Coverage of HIV Pre-Exposure Prophylaxis by the Statutory Health Insurance in Germany
Authors: Valbert Frederik , Schmidt Daniel , Kollan Christian , Dröge Patrik , Klein Melanie , Schneider Udo , Friebe Martin , Wasem Jürgen , Neumann Anja 
Published: August 2024

AbstractHuman immunodeficiency virus pre-exposure prophylaxis (PrEP) is considered as an effective protection against a human immunodeficiency virus (HIV) infection. However, it is still unclear, how PrEP use is associated with the incidence of sexually transmitted infections (STI) other than HIV. PrEP became reimbursable in Germany from September 1, 2019 for persons with statutory health insurance (SHI). With the EvE-PrEP study, the Federal Ministry of Health commissioned the evaluation of the effects of the new reimbursement situation in Germany. In the presented module of the EvE-PrEP study, routine data from three large German SHI funds were analyzed in anonymized form for the period January 1, 2019 to March 31, 2020. Data were analyzed regarding: Characteristics and adherence of PrEP users, treatment success of PrEP, and changes in STI incidence rates before and since PrEP use. The cooperating SHI funds collectively covered about 52% of the overall population in Germany in 2019. A total of 7102 persons with PrEP use were included into the analysis. These were predominantly male (99%), on average 37.4 years old and a high proportion of persons lived in large cities. The average quotient of PrEP daily defined doses and assumed days on PrEP was 87%. The average STI rates normalized per 100 person-years at individual level pre PrEP did not statistically significant differ compared to since PrEP (chlamydia: 17.5 vs. 17.6, gonococcal infection: 29.1 vs. 30.7, and syphilis: 14.6 vs.13.6). A large data set was used to evaluate the introduction of PrEP as a SHI benefit in Germany. A potentially suspected increase in bacterial STI incidence rates was not found. A rather high average adherence rate was observed. The very high proportion of men and people from the largest German cities among PrEP users is striking. These results could indicate barriers to PrEP access for people at risk of HIV, especially if they are women or people living in less urban areas.
Avenues for Coexistence: How Perception of Costs and Benefits Shape Attitudes towards Wolves
Authors: Lino Sofia , Carvalho João , Fonseca Carlos , Rosalino Luís Miguel 
Published: August 2024

AbstractHuman dimensions play a pivotal role in wolf management and conservation. To offer an informed basis to improve Human-Wolf coexistence, we explore how socio-demographic factors, fear, knowledge, and perceptions of costs and benefits of wolf presence drive human attitudes in the southern area of the Douro River, Portugal, a region inhabited by a small and endangered wolf population. We interviewed 220 people (175 from the general public, 13 hunters, and 32 livestock owners) through a semi-structured survey organized on a 5-point Likert scale. Public and hunter respondents exhibited neutral to positive attitudes, whereas livestock owners expressed negative to neutral attitudes and revealed a Not-In-My-Backyard sentiment. We found that positive attitudes were linked to a greater receptiveness to increased wolf numbers, particularly in areas of irregular wolf presence. Fear was a significant driver of public attitudes, while the presence of wolves influenced livestock owners’views. For both groups, attitudes were also influenced by perceived costs and benefits. Knowledge about wolves did not significantly influence attitudes, with scores being consistently low across groups, and the myth of reintroduction persisting. Thus, management actions should address the concerns and complaints of individuals directly affected by wolves, dispel common fears and myths, and emphasize the ecological and economic benefits of wolf presence in the territory. Media outlets can serve as strategic partners in engaging the neutral population through untargeted interventions. Prioritizing the input of all groups, including conservationists, is essential for establishing common ground and ensuring sustained coexistence.
Co-design Pedagogy for Computational Thinking Education in K-12: A Systematic Literature Review
Authors: Sunday Amos Oyelere , Agbo Friday Joseph , Suhonen Jarkko 
Published: August 2024

AbstractThe recent popularity of computational thinking (CT) and the desire to apply CT in our daily lives have prompted the need for a successful pedagogical technique for learning CT in K-12 education. The application of co-design pedagogical techniques has the potential to improve students’ CT learning through knowledge sharing and the creation of ideas to solve problems and develop an artifact. However, there is a limited understanding of how co-design pedagogical techniques have been explored to foster CT learning, which could hamper the successful use of co-design as a pragmatic teaching approach. This study examined the ways in which co-design pedagogical techniques have been applied in CT education by implementing a systematic literature review (PRISMA protocol) to document the review analysis. A total of 26 articles that met the inclusion criteria for this study were reviewed. Findings in this study revealed that workshops are the most utilized co-design learning setting and, as expected, the collaborative technique is the co-design pedagogical technique most frequently adopted for implementing CT in K-12 education. NetLogo is the most frequently used co-design tool for teaching and learning CT in K-12 education, and an interdependence exists between NetLogo and the Common Online Data Analysis Platform. Co-design also helps teachers develop the ability to use co-design pedagogical techniques to learn, create content, and integrate CT into their various subjects. This study contributes to practical knowledge by unraveling and advocating the use of dialogical, prompting, framing, and game-based techniques as co-design pedagogical techniques for K-12 teachers and also helps teachers identify useful co-design tools for learning CT.
Organizational Practices for the Inclusion of People with Disabilities. A Scoping Review
Authors: van Berkel Rik , Breit Eric 
Published: August 2024

Abstract
Purpose
The purpose of the scoping review presented in this article is to map the state-of-the-art and development of empirical research of organizational practices designed to include people with disabilities. It contributes to debates on demand-side approaches in promoting the labour-market participation of people with disabilities.

Methods
A literature search took place in PsychINFO, Web of Science, Sociological Abstracts and Sociological Index. Articles included empirical studies published between 2000 and 2023.

Results
The search resulted in 10,535 unique articles of which 146 were included in the review. Organizational inclusion practices have received increasing attention in academic journals in a variety of research fields. In terms of content two groups of studies can be distinguished: hiring studies and studies focusing on organizational practices aimed at employees with disabilities. Hiring studies include studies analysing relationships between a large range of factors and actual hiring or intention to hire as well as studies of a more exploratory nature. Studies focusing on employees with disabilities look at outcomes of specific organizational practices; the conditions promoting their implementation; or explore practices in organizations employing people with disabilities.

Discussion
Based on the findings of the review three suggestions for future research are discussed: (i) internationally comparative studies; (ii) specific attention to small and medium sized enterprises in studies of inclusion; (iii) systematic reviews as follow-ups to scoping reviews.
Health-related quality of life is an independent predictor of mortality and hospitalisations in transthyretin amyloid cardiomyopathy: a prospective cohort study
Authors: Poledniczek Michael , Kronberger Christina , Willixhofer Robin , Ermolaev Nikita , Cherouny Bernhard , Dachs Theresa-Marie , Rettl René , Binder-Rodriguez Christina , Camuz Ligios Luciana , Gregshammer Bernhard , Kammerlander Andreas Anselm , Kastner Johannes , Bergler-Klein Jutta , Duca Franz , Badr Eslam Roza 
Published: August 2024

Abstract
Purpose
Transthyretin amyloid cardiomyopathy (ATTR-CM) is associated with severely impaired health-related quality of life (HRQL). HRQL is an independent predictor of outcome in heart failure (HF), but data on patients with ATTR-CM is scarce. This study therefore aims to evaluate the association of HRQL with outcome in ATTR-CM.

Methods
Patients from our prospective ATTR-CM registry were assessed using the Kansas City cardiomyopathy questionnaire (KCCQ), the Minnesota living with HF questionnaire (MLHFQ), and the EuroQol five dimensions questionnaire (EQ-5D). Cox regression analysis was utilised to assess the impact of HRQL on all-cause mortality.

Results
167 patients [80 years; interquartile range (IQR): 76–84; 80.8% male] were followed for a median of 27.6 (IQR: 9.7–41.8) months. The primary endpoint of all-cause mortality was met by 43 (25.7%) patients after a median period of 16.2 (IQR: 9.1–28.1) months. In a univariate Cox regression for mortality, a 10-point change in the KCCQ implied a hazard ratio (HR) of 0.815 [95%-confidence interval (CI): 0.725–0.916; p = 0.001], in the EQ-5D VAS of 0.764 (95%-CI: 0.656–0.889; p < 0.001), and 1.163 (95%-CI: 1.114–1.433; p < 0.001) in the MLHFQ. After adjustment for established biomarkers of HF, all-cause mortality was predicted independently by the EQ-5D VAS (HR: 0.8; 95%-CI: 0.649–0.986; p = 0.037; per 10 points) and the MLHFQ (HR: 1.228; 95%-CI: 1.035–1.458; p = 0.019; per 10 points).

Conclusion
HRQL is a predictor of outcome in ATTR-CM. The EQ-5D VAS and the MLHFQ predict survival independent of biomarkers of HF.
Spaziergang in die Zukunft der Altenpflege: Wie Robis die Lebensqualität von Oldies verbessern könnten
Authors: Ďuranová Lenka , Schrödel Frank , Rösner Marlene 
Published: August 2024

ZusammenfassungIn der Altenpflege herrscht Fachkräftemangel. Dieser beeinträchtigt Organisationen, Personal, Pflegebedürftige sowie Angehörige und erfordert innovative Lösungen. In der Berufspraxis entstand eine konkrete Forderung: Roboter, die mit den Älteren spazieren gehen. Dieser gehen wir nach. In diesem Beitrag skizzieren wir die Notwendigkeit einer Technologieinnovation in der Altenpflege aus wirtschaftspsychologischer Sicht, danach potenzielle Vorteile des begleitenden Roboters, seine Anwendungsszenarien, Hindernisse bei der Einführung und die notwendigen Entwicklungsschritte. Schließlich appellieren wir an die Praxis, die Technologieentwicklung zu unterstützen.