bluuebunny/crossref_metadata_2025_split huggingface dataset:
Seeing the forest beyond the trees
Authors: Saatchi Sassan , Mascaro Joseph , Xu Liang , Keller Michael , Yang Yan , Duffy Paul , Espírito‐Santo Fernando , Baccini Alessandro , Chambers Jeffery , Schimel David 
Published: November 2014

AbstractIn a recent paper (Mitchard et al. 2014, Global Ecology and Biogeography, 23, 935–946) a new map of forest biomass based on a geostatistical model of field data for the Amazon (and surrounding forests) was presented and contrasted with two earlier maps based on remote‐sensing data Saatchi et al. (2011; RS1) and Baccini et al. (2012; RS2). Mitchard et al. concluded that both the earlier remote‐sensing based maps were incorrect because they did not conform to Mitchard et al. interpretation of the field‐based results. In making their case, however, they misrepresented the fundamental nature of primary field and remote‐sensing data and committed critical errors in their assumptions about the accuracy of research plots, the interpolation methodology and the statistical analysis. By ignoring the large uncertainty associated with ground estimates of biomass and the significant under‐sampling and spatial bias of research plots, Mitchard et al. reported erroneous trends and artificial patterns of biomass over Amazonia. Because of these misrepresentations and methodological flaws, we find their critique of the satellite‐derived maps to be invalid.
Diabetes increases pancreatitis induced systemic inflammation but has little effect on inflammation and cell death in the lung
Authors: Zechner Dietmar , Spitzner Marie , Müller‐Graff Tassilo , Vollmar Brigitte 
Published: November 2014

SummaryAcute pancreatitis (AP) can lead to a systemic inflammatory response that often results in acute lung injury and single or multiple organ failure. In a previous study we demonstrated that diabetes aggravates the local pathophysiological process during AP. In this study we explore, if diabetes also increases pancreatitis induced systemic inflammation and causes lung injury. Acute pancreatitis was induced in untreated and streptozotocin‐treated diabetic mice by injection of cerulein. Systemic inflammation was studied by IL‐6 ELISA in blood plasma and white blood cell count. Lung inflammation and lung injury were quantified by chloroacetate esterase staining, evaluation of the alveolar cellularity index and cleaved caspase‐3 immunohistochemistry. In normoglycaemic mice AP increased the IL‐6 concentration in plasma and caused lymphocytopenia. Diabetes significantly increased the IL‐6 concentration in plasma and further reduced the number of lymphocytes during AP, whereas diabetes had little effect on these parameters in the absence of pancreatitis. However, diabetes only marginally increased lung inflammation and did not lead to cell death of the lung epithelium during AP. We conclude that diabetes increases parameters of systemic inflammation during AP, but that this increase is insufficient to cause lung injury.
Male eco‐fashion: a market reality
Authors: D'Souza Clare , Gilmore Andrew J. , Hartmann Patrick , Apaolaza Ibáñez Vanessa , Sullivan‐Mort Gillian 
Published: November 2014

AbstractWith the fashion industry striving for competitive advantage, eco‐fashions provide an opportunity to distinguish environmentally friendly products from other fashion products. However, the viability of these eco‐fashion brands is questionable. An exploratory study is conducted to explain men's differences, particularly, as clothing styles vary for men and women. The research examines if men's purchase intent would make a difference to the eco‐fashion industry. A random sample is collected to examine men's purchase intentions for eco‐clothing by product attributes, environmental concerns and sustainable behaviour. Partial least squares is used to empirically test the sample. A conceptual model is developed. It was found that there are four significant exogenous variables, environmental concern, sustainable pricing, sustainable behaviour and sustainable branding with a moderately strong, negatively signed coefficient path. Perceived consumer effectiveness and faith in others are not found to be significant moderators. This defined male segment makes several theoretical contributions as well as generating useful recommendations for marketing practitioners.
Adolescents' sustainability concerns and reasons for not consuming sustainably
Authors: Francis Julie E. , Davis Teresa 
Published: November 2014

AbstractMany consumers report being concerned about sustainability but they do not necessarily consume in a sustainable manner. Understanding why this occurs is vital to encouraging sustainable consumption practices. Understanding the phenomenon in relation to adolescents is particularly important. In addition to being a significant segment of current consumers, adolescents are learning consumption habits and preferences that they will carry into adulthood. This research contributes to the domain by fulfilling two research objectives. The first objective was to develop and use a scale for measuring adolescents' sustainability concerns (ASC). The second objective was to identify and examine adolescents' reasons for not consuming sustainably. The research used a three‐stage multi‐method design that included small group interviews and two online surveys with adolescents aged 12 to 17 years. The ASC scale that we produced identifies 14 key sustainability concerns across the dimensions of environment, well‐being and society. The reasons for not consuming sustainably varied across these dimensions. For example, the most frequently reported reasons in the environmental dimension included cost and convenience whereas peer pressure and hedonic preferences were the dominant reasons for well‐being. More broadly, three groups of reasons for unsustainable consumption emerged. These included (i) limited application of sustainability concerns across consumption; (ii) deviating from concerns due to competing priorities; and (iii) limiting or eliminating personal responsibility. The contributions of this research have theoretical, methodological and practical implications for consumer researchers, social marketers and policy makers.
A randomized controlled trial of an educational programme to improve self‐care in Brazilian patients following percutaneous coronary intervention
Authors: Furuya Rejane K. , Arantes Eliana C. , Dessotte Carina A.M. , Ciol Marcia A. , Hoffman Jeanne M. , Schmidt André , Dantas Rosana A.S. , Rossi Lidia A. 
Published: November 2014

AbstractAimsTo test an educational programme with telephone follow‐up to improve self‐care in Brazilian patients who underwent percutaneous coronary intervention.BackgroundPercutaneous coronary intervention has been established as a treatment for coronary disease. However, additional intervention is needed to improve self‐care for individuals who undergo this procedure to reduce further disease. Telephone follow‐up is one strategy that has been used to improve chronic disease self‐care.DesignRandomized controlled trial. Trial registration: ClinicalTrials.gov, NCT01341093.MethodsSixty patients who were preparing for their first percutaneous coronary intervention between 2011–2012 were randomly allocated to an educational programme with telephone follow‐up (N = 30) or a control group (N = 30). Perceived health status was assessed with the Medical Outcomes Study 36‐Item Short Form. Self‐efficacy, symptoms of anxiety and depression and medication adherence were also assessed. Measures were collected before intervention (baseline) and 6 months later.ResultsBoth groups improved from baseline to 6 months in the ‘Physical Component Summary’ and in the domains of ‘Physical Functioning’, ‘Role–Emotional’ and ‘Role–Physical’. The educational programme group showed a reduction in anxiety from baseline to 6‐month follow‐up, while the control group showed a slight increase. No differences in symptoms in depression and self‐efficacy were found and both groups reported high levels of medication adherence.ConclusionThe educational programme with telephone follow‐up is a promising intervention as it led to reduction in anxiety for those receiving the educational programme. Further improvements in timing and focus of the educational programme, such as targeting emotional and social lifestyle changes, might be warranted.
Effect of peer education on self‐management and psychological status in type 2 diabetes patients with emotional disorders
Authors: Liu Yan , Han Ying , Shi Jieli , Li Ruixia , Li Sufen , Jin Nana , Gu Yong , Guo Honglei 
Published: November 2014

AbstractAims/IntroductionThe purpose of the present study was to assess the effect of peer education in type 2 diabetes patients with emotional disorders on the metabolic index and psychological status.Materials and MethodsEducators use psychological scales to screen type 2 diabetes patients with emotional disorders. Participants were divided into usual and peer education groups. Both groups received usual diabetes education. Peer leaders were recruited to provide support with the peer education group for 6 months. The metabolic index, diabetes knowledge, self‐management, diabetes‐related distress, emotional status and quality of life were compared at the end of the study.ResultsA total of 127 patients participated in the study. There were 20 peer leaders engaged in the study as volunteers for peer education. All participants completed the study and fulfilled the scales. Improvements in the peer education group were significant compared with the usual education group with respect to anxiety (49.0 ± 9.65 vs 54.0 ± 8.48), depression (51.3 ± 7.97 vs 55.8 ± 7.52), diabetes knowledge (18.8 ± 2.46 vs 16.3 ± 2.08), distress (2.67 ± 0.55 vs 3.02 ± 0.56), self‐management (66.5 ± 4.26 vs 62.4 ± 5.88) and quality of life (−1.98 ± 0.82 vs −2.50 ± 0.71), whereas no significant difference existed with respect to the metabolic index.ConclusionsPeer education, providing more attention to diabetes patients with emotional disorders, is a preferred model for delivering care.
Photoreceptors in diabetic retinopathy
Authors: Kern Timothy S , Berkowitz Bruce A 
Published: November 2014

AbstractAlthough photoreceptors account for most of the mass and metabolic activity of the retina, their role in the pathogenesis of diabetic retinopathy has been largely overlooked. Recent studies suggest that photoreceptors might play a critical role in the diabetes‐induced degeneration of retinal capillaries, and thus can no longer be ignored. The present review summarizes diabetes‐induced alterations in photoreceptor structure and function, and provides a rationale for further study of a role of photoreceptors in the pathogenesis of the retinopathy.
Mate‐sampling costs and sexy sons
Authors: Kokko H. , Booksmythe I. , Jennions M. D. 
Published: November 2014

AbstractCostly female mating preferences for purely Fisherian male traits (i.e. sexual ornaments that are genetically uncorrelated with inherent viability) are not expected to persist at equilibrium. The indirect benefit of producing ‘sexy sons’ (Fisher process) disappears: in some models, the male trait becomes fixed; in others, a range of male trait values persist, but a larger trait confers no net fitness advantage because it lowers survival. Insufficient indirect selection to counter the direct cost of producing fewer offspring means that preferences are lost. The only well‐cited exception assumes biased mutation on male traits. The above findings generally assume constant direct selection against female preferences (i.e. fixed costs). We show that if mate‐sampling costs are instead derived based on an explicit account of how females acquire mates, an initially costly mating preference can coevolve with a male trait so that both persist in the presence or absence of biased mutation. Our models predict that empirically detecting selection at equilibrium will be difficult, even if selection was responsible for the location of the current equilibrium. In general, it appears useful to integrate mate sampling theory with models of genetic consequences of mating preferences: being explicit about the process by which individuals select mates can alter equilibria.
The Patient-Centered Discharge—An Electronic Discharge Process Is Associated With Improvements in Quality and Patient Satisfaction
Authors: Buckler Lacey T. , Teasdale Carla , Turner Matthew , Schadler Aric , Schwieterman Tracy M. , Campbell Charles L. 
Published: November 2014

Abstract:
In this retrospective cohort study, 100 records were randomly selected from the intervention period (April 2012) and the control period (April 2011). The hospital's institutional database was queried to compare mortality, length of stay, and patient satisfaction, in the year prior to and the year after the integration of the new process. A chart review was performed to determine if the reengineered process was associated with an improvement in documentation. A scoring system was developed to gauge the quality and timeliness of the process. Institutional data regarding length of stay, mortality, patient satisfaction, and core measures compliance were compared for the pre- and postimplementation of the new process. The reengineered discharge process was associated with an improvement in patient satisfaction and in the quality of the discharge materials as measured by the “patient-centered transitions of care (PCTC) score.” These improvements occurred without a significant increase in the time to complete a discharge.
A redesigned discharge process resulted in system-wide improvements in the quality of information provided to the patient and their outpatient providers. This intervention was associated with an improvement in compliance with core measures, improvements in patient satisfaction and timeliness of discharge summary preparation.
The course and the anatomo‐functional relationships of the optic radiation: a combined study with ‘post mortem’ dissections and ‘in vivo’ direct electrical mapping
Authors: Sarubbo Silvio , De Benedictis Alessandro , Milani Paola , Paradiso Beatrice , Barbareschi Mattia , Rozzanigo Umbero , Colarusso Enzo , Tugnoli Valeria , Farneti Marco , Granieri Enrico , Duffau Hugues , Chioffi Franco 
Published: November 2014

AbstractEven if different dissection, tractographic and connectivity studies provided pure anatomical evidences about the optic radiations (ORs), descriptions of both the anatomical structure and the anatomo‐functional relationships of the ORs with the adjacent bundles were not reported. We propose a detailed anatomical and functional study with ‘post mortem’ dissections and ‘in vivo’ direct electrical stimulation (DES) of the OR, demonstrating also the relationships with the adjacent eloquent bundles in a neurosurgical ‘connectomic’ perspective. Six human hemispheres (three left, three right) were dissected after a modified Klingler's preparation. The anatomy of the white matter was analysed according to systematic and topographical surgical perspectives. The anatomical results were correlated to the functional responses collected during three resections of tumours guided by cortico‐subcortical DES during awake procedures. We identified two groups of fibres forming the OR. The superior component runs along the lateral wall of the occipital horn, the trigone and the supero‐medial wall of the temporal horn. The inferior component covers inferiorly the occipital horn and the trigone, the lateral wall of the temporal horn and arches antero‐medially to form the Meyer's Loop. The inferior fronto‐occipital fascicle (IFOF) covers completely the superior OR along its entire course, as confirmed by the subcortical DES. The inferior longitudinal fascicle runs in a postero‐anterior and inferior direction, covering the superior OR posteriorly and the inferior OR anteriorly. The IFOF identification allows the preservation of the superior OR in the anterior temporal resection, avoiding post‐operative complete hemianopia. The identification of the superior OR during the posterior temporal, inferior parietal and occipital resections leads to the preservation of the IFOF and of the eloquent functions it subserves. The accurate knowledge of the OR course and the relationships with the adjacent bundles is crucial to optimize quality of resection and functional outcome.
Comparison of different technologies for noninvasive skin tightening
Authors: Pritzker Rachel N. , Hamilton Heather K. , Dover Jeffrey S. 
Published: November 2014

SummaryFacial skin laxity is a bothersome sign of aging. In the past, the only option for treating laxity was surgery. While surgical lifting remains the gold standard, there has been a growing demand among patients for less invasive techniques. Patients are increasingly seeking procedures with little to no downtime, lower risk profiles, and a more natural appearance. The industry has responded to these demands with an emergence of noninvasive skin tightening devices. The rate of development and marketing of these devices has increased exponentially within the last decade. Whereas we previously had no options, now we are faced with many choices. How do we choose which technology is best for our patients? While there is a paucity of comparative trials to date, a critical exploration of these technologies is worthwhile. The underlying mechanism of action of all these treatments is essentially the same: heating of the dermis and subdermal areas while minimizing injury to the epidermis. In this article, we outline the different technologies and highlight the differences to help guide us in selecting the right treatment.
The impact of upper facial lines and psychological impact of crow's feet lines: content validation of the Facial Line Outcomes (FLO‐11) Questionnaire
Authors: Yaworsky Andrew , Daniels Selena , Tully Shannon , Beddingfield Frederick , Kowalski Jonathan , Fitzgerald Kristina , Somogyi Christine , Burgess Somali M 
Published: November 2014

SummaryBackgroundTreatments for upper facial lines (UFL), the most visible sign of aging, are of interest to patients and clinicians alike. Patient‐reported outcomes (PROs) are valuable in evaluating the impact of such treatments; however, regulatory recommendations have stipulated that the patient perspective be central in developing these assessments.Objectives(1) To evaluate the content validity of the Facial Lines Outcomes Questionnaire, a PRO instrument developed to assess upper facial line impacts, according to the regulatory guidance of the United States Food and Drug Administration and (2) assess whether it adequately measures the psychological impacts associated with crow's feet lines (CFL) (lateral canthal lines) from the patient perspective.MethodsTwo patient groups participated in face‐to‐face qualitative interviews. One group included patients with UFL (Group 1, n = 25 interviews), and the other included patients specifically with CFL (Group 2, n = 41 interviews). Each interview consisted of a concept elicitation and cognitive debriefing phase.ResultsInterviews with both groups elicited all key concepts of the instrument, including “bothered by facial lines”; “looking older”; “looking less attractive”; and looking “tired,” “stressed,” or “angry.” Most Group 2 patients (n = 35, 85%) agreed that the instrument adequately assessed the psychological impacts associated with CFL. During cognitive debriefing, the majority of patients in both groups agreed the instrument was understandable, comprehensive, and easy to complete.ConclusionsThe Facial Line Outcomes Questionnaire is an appropriate and valid tool to assess the impact of UFL and the psychological impacts associated with CFL.
Discourse in a Material World
Authors: Hardy Cynthia , Thomas Robyn 
Published: November 2014

AbstractWe challenge recent assertions that discourse studies cannot de facto address materiality. We demonstrate how a Foucauldian theorization of discourse provides a way to analyse the co‐constitutive nature of discursive and material processes, as well as explore the power relations implicated in these relationships. To illustrate our argument, we identify exemplary studies that have effectively combined a study of discourse and different aspects of materiality – bodies, objects, spaces, and practices. In doing so, we show how discourse scholars are able to study both materiality and power relations.
Resveratrol suppresses TPA‐induced matrix metalloproteinase‐9 expression through the inhibition of MAPK pathways in oral cancer cells
Authors: Lin Feng‐Yan , Hsieh Yi‐Hsien , Yang Shun‐Fa , Chen Chang‐Tai , Tang Chih‐Hsin , Chou Ming‐Yung , Chuang Yi‐Ting , Lin Chiao‐Wen , Chen Mu‐Kuan 
Published: November 2014

BackgroundNaturally occurring agents, such as resveratrol, have been determined to benefit health. Numerous studies have demonstrated that resveratrol has antioxidative, cardioprotective, and neuroprotective properties. However, the effect of resveratrol exerts on the metastasis of oral cancer cells remains unclear. In this study, we investigated the effect the anti‐invasive activity of resveratrol on a human oral cancer cell line (SCC‐9) in vitro and the underlying mechanisms.MethodsCell viability was examined by MTT assay, whereas cell motility was measured by migration and wound‐healing assays. Zymography, reverse‐transcriptase polymerase chain reaction (PCR), and promoter assays confirmed the inhibitory effects of resveratrol on matrix metalloproteinase‐9 (MMP‐9) expression in oral cancer cells.ResultsWe established that various concentrations (0–100 μM) of resveratrol inhibited the 12‐O‐tetradecanoylphorbol‐13‐acetate (TPA)‐induced migration capacities of SCC‐9 cells and caused no cytotoxic effects. Zymography and Western blot analyses suggested that resveratrol inhibited TPA‐induced MMP‐9 gelatinolytic activity and protein expression. In addition, the results indicated that resveratrol inhibited the phosphorylation of c‐Jun N‐terminal kinase (JNK)1/2 and extracellular‐signal‐regulated kinase (ERK)1/2 involved in downregulating protein expression and the transcription of MMP‐9.ConclusionIn summary, resveratrol inhibited MMP‐9 expression and oral cancer cell metastasis by downregulating JNK1/2 and ERK1/2 signals pathways and, thus, exerts beneficial effects in chemoprevention.
Melatonin prevents cell death and mitochondrial dysfunction via a SIRT1‐dependent mechanism during ischemic‐stroke in mice
Authors: Yang Yang , Jiang Shuai , Dong Yushu , Fan Chongxi , Zhao Lei , Yang Xiangmin , Li Juan , Di Shouyin , Yue Liang , Liang Guobiao , Reiter Russel J. , Qu Yan 
Published: November 2014

AbstractSilent information regulator 1 (SIRT1), a type of histone deacetylase, is a highly effective therapeutic target for protection against ischemia reperfusion (IR) injury (IRI). Previous studies showed that melatonin preserves SIRT1 expression in neuronal cells of newborn rats after hypoxia–ischemia. However, the definite role of SIRT1 in the protective effect of melatonin against cerebral IRI in adult has not been explored. In this study, the brain of adult mice was subjected to IRI. Prior to this procedure, the mice were given intraperitoneal with or without the SIRT1 inhibitor, EX527. Melatonin conferred a cerebral‐protective effect, as shown by reduced infarct volume, lowered brain edema, and increased neurological scores. The melatonin‐induced upregulation of SIRT1 was also associated with an increase in the anti‐apoptotic factor, Bcl2, and a reduction in the pro‐apoptotic factor Bax. Moreover, melatonin resulted in a well‐preserved mitochondrial membrane potential, mitochondrial Complex I activity, and mitochondrial cytochrome c level while it reduced cytosolic cytochrome c level. However, the melatonin‐elevated mitochondrial function was reversed by EX527 treatment. In summary, our results demonstrate that melatonin treatment attenuates cerebral IRI by reducing IR‐induced mitochondrial dysfunction through the activation of SIRT1 signaling.