bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of an educational intervention using e-mail on diet quality
Authors: Cristina Moura Bombem Kelly , Silva Canella Daniela , Henrique Bandoni Daniel , Constante Jaime Patricia 
Published: October 2014

Purpose
– The purpose of this paper is to assess the impact of a worksite nutritional intervention on the dietary quality of adult workers from the city of São Paulo, Brazil.

Design/methodology/approach
– A 6-month controlled community trial was performed involving 236 workers from São Paulo, Brazil. The intervention was implemented through interactive software that sends recommendations about diet and physical activity by e-mail. Data were collected for all participants using a 24-hour dietary recall and also for a sub-sample containing 25.4 per cent of the participants. Diet quality was assessed by the diet quality index adjusted (DQIa) comprising 10 components (grains and tubers; vegetables; fruits; milk and dairy products; meat and eggs; beans and legumes; total fat; saturated fat; sodium; and variety), scored from 0 (inadequate consumption) to 10 (recommended consumption). Intragroup impact of the intervention was assessed according to variation in total DQIa, its components and energy consumption. Impact adjusted between groups was also determined.

Findings
– The intervention yielded improvements in DQIa and for the components cereals and tubers, vegetables, milk and dairy products and total fat. The workers who had a worst diet quality before the study were more susceptible to the intervention, which improved significantly the diet quality, with an adjusted impact of +6.4 points.

Originality/value
– Few behavioral interventions have been performed using technologies, like e-mail, to encourage a healthy lifestyle. This study shows the importance of the counseling to promote a higher-quality diet, which can result in control of the obesity.
Evaluation of the satiating properties of a fish protein hydrolysate among overweight women
Authors: Zaïr Yassine , Duclos Elisa , Housez Béatrice , Vergara Coralie , Cazaubiel Murielle , Soisson Florian 
Published: October 2014

Purpose
– This paper aims to investigate the satiety properties of a fish protein hydrolysate (blue whiting muscle hydrolysate, BWMH). Protein consumption is associated with higher satiety, protein being considered as the more satiating macronutrient. This property is extensively investigated in regard to weight management.

Design/methodology/approach
– Fifteen overweight women were included in a crossover design study. Subjects consumed 1 g of BWMH or placebo twice daily and sensations associated with satiety were recorded every day.

Findings
– Significant differences, in favour of BWMH, were highlighted on the desire to eat something sweet at T90 min (p < 0.05) and on plasma glucose at T270 min (p < 0.05).

Research limitations/implications
– This study demonstrates effect of BWMH on appetite. Indeed promising data were reported in favour of the test product, in particular on the desire to eat something sweet and on glucose levels. Some additional investigations will be necessary to support these data and those observed in in vitro and in vivo models.

Originality/value
– After promising pre-clinical data, this study is a first investigation of health benefits of BWMH supplementation in humans.
‘I will return as millions?’
Authors: Levingston Oliver 
Published: October 2014

Purpose
– The purpose of this paper is to present reflections on the contradictions between structure and agency in theories of the Bolivian Revolution, 2000-2005. Most studies into the trajectory and outcomes of the revolutionary period in Bolivia between 2000 and 2005 tend to emphasise on the primary role of structural factors or social movements in shifting the terrain of political debate. This paper argues this represents a false dichotomy and discounts the value of this debate. In doing so, it seeks to highlight the need for research that focuses on the role of institutional variables that mediate between structure and agency.

Design/methodology/approach
– The paper uses theories of the Bolivian Revolution, which occurred between 2000 and 2005, to highlight the way theory shapes – and is shaped by – the political organisations that espouse it. This constructivist thesis is applied to conceptions of neoliberalism and Katarismo, an ideology of indigenous liberation, based in Andean-Aymara history. The intellectual and political projects of each approach are demarcated. Theories that privilege either the intellectual project or political project in their narrative of the Bolivian Revolution are then queried.

Findings
– As a consequence of this analysis, the paper concludes by emphasizing the need for political organisation and theory to be considered dialectically along the lines of Gogol (2012). It argues that further research into institutions is required to appreciate why some post-neoliberal projects flourish while others fragment.

Originality/value
– The paper proposes a modified understanding of the interplay between structure and agency in conceptions of the Bolivian Revolution (2000-2005) and suggests an original approach to resolving the underlying questions that motivate these debates.
Insights about the profession: questionable norms and the marginalization of practice
Authors: Murphy Joseph 
Published: October 2014

Purpose
– The purpose of this article is to discuss concerns about dominant university norms and values and their appropriateness in higher education in the 21st century. It also explains how universities marginalize practice through their practices and values.

Design/methodology/approach
– This article employs the tools of the essayist and historian, primarily reflective inquiry and historical analysis.

Findings
– The primary value of this essay is to point to a new direction for academic departments of school leadership and to place academic units primarily in the service of practice not the academic disciplines. Many of the unquestioned core values and ways of operating in universities require serious review.

Originality/value
– The article contributes in a fresh way critique about values and norms in universities.
Weighing up the commitment: A grounded theory of the transition from occupational therapy clinician to academic
Authors: Murray Carolyn , Stanley Mandy , Wright Shelley 
Published: October 2014

Background/aimGrowth in the number of occupational therapy programmes in Australia has resulted in a critical shortage of academics. When experienced clinicians are recruited into academia, they may find the transition process difficult. The study aimed to explore clinicians’ perspectives of what happens when they transition into academia.MethodA constructivist grounded theory approach was used in this qualitative research project. Recruitment was conducted using purposive and theoretical sampling from occupational therapy programmes in Australia. Interview transcripts were analysed using constant comparative method through a process of open, axial, selective and theoretical coding.ResultsSixteen participants engaged in semi‐structured in‐depth interviews. The theory of transition into academia included a process of ‘weighing up the commitment’ to academia and the core category of ‘a good fit for me’. The transition was characterised by the taxing nature of the work, the need to learn multiple aspects of a new role, the different values and beliefs in an academic environment and the amount of time it took to achieve success. Participants underwent a shift in identity to adjust to the academic environment and eventually reached a point where they were able to judge if academia suited them.ConclusionAustralian universities have long‐standing cultural practices which differ considerably from clinical settings. Transitioning from a clinical to an academic occupational therapy role requires complex adjustments to values, beliefs and identity. The process involved consideration by the new academics of their ‘fit’ for academia, and how committed they were to stay.
A multi‐site randomised controlled trial of evidence‐based supported employment for adults with severe and persistent mental illness
Authors: Waghorn Geoffrey , Dias Shannon , Gladman Beverley , Harris Meredith , Saha Sukanta 
Published: October 2014

Background/aimThe Individual Placement and Support (IPS) approach is an evidence‐based form of supported employment for people with severe and persistent mental illness. This approach is not yet widely available in Australia even though there is mounting evidence of its generalisability outside the USA. One previous Australian randomised controlled trial found that IPS is effective for young people with first episode psychosis. The aim of the current trial was to assess the effectiveness of evidence‐based supported employment when implemented for Australian adult consumers of public mental health services by utilising existing service systems.MethodsA four‐site randomised control trial design (n = 208) was conducted in Brisbane (two sites), Townsville and Cairns. The intervention consisted of an IPS supported employment service hosted by a community mental health team. The control condition was delivered at each site by mental health teams referring consumers to other disability employment services in the local area.ResultsAt 12 months, those in the IPS condition had 2.4 times greater odds of commencing employment than those in the control condition (42.5% vs. 23.5%). The conditions did not differ on secondary employment outcomes including job duration, hours worked, or job diversity. Attrition was higher than expected in both conditions with 28.4% completing the baseline interview but taking no further part in the study.ConclusionThe results support previous international findings that IPS‐supported employment is more effective than non‐integrated supported employment. IPS can be successfully implemented this way in Australia, but with a loss of effect strength compared to previous USA trials.
Development and validation of the activity significance personal evaluation (ASPEn) scale
Authors: Mallinson Trudy , Schepens Niemiec Stacey L. , Carlson Mike , Leland Natalie , Vigen Cheryl , Blanchard Jeanine , Clark Florence 
Published: October 2014

Background/aimEngagement in desired occupations can promote health and wellbeing in older adults. Assessments of engagement often measure frequency, amount or importance of specific activities. This study aimed to develop a scale to measure older adults’ evaluation of the extent to which their everyday activities are contributing to their health and wellness.MethodsEighteen items, each scored with a seven‐point rating scale, were initially developed by content experts, covering perceptions of how daily activities contribute to physical and mental health, as well as satisfaction and activity participation in the last six months. Rasch analysis methods were used to refine the scale using the pencil and paper responses of 460 community‐living older adults.ResultsInitial Rasch analysis indicated three unlabelled rating scale categories were seldom used, reducing measurement precision. Five items were conceptually different by misfit statistics and principal component analysis. Subsequently, those items were removed and the number of rating scale steps reduced to 4. The remaining 13‐item, 4‐step scale, termed the Activity Significance Personal Evaluation (ASPEn), formed a unidimensional hierarchy with good fit statistics and targeting. Person separation reliability (2.7) and internal consistency (.91) indicated the tool is appropriate for individual person measurement. Relative validity indicated equivalence between Rasch measures and total raw scores.ConclusionsASPEn is a brief, easily administered assessment of older adults’ perception of the contribution of everyday activities to personal health and wellness. ASPEn may facilitate occupational therapy practice by enabling clinicians to assess change in meaning of an older adult's activity over time.
Isotretinoin‐induced arthritis mimicking both rheumatoid arthritis and axial spondyloarthritis
Authors: Yilmaz Tasdelen Ozlem , Yurdakul Fatma Gul , Duran Semra , Bodur Hatice 
Published: October 2014

AbstractIsotretinoin is used for the treatment of various acne lesions that are resistant to other treatments. The most frequent rheumatologic side effect of isotretinoin is transient muscle and/or joint pains. Here, we report a case with bilateral wrist and metacarpophalangeal joint arthritis and unilateral sacroiliitis associated with isotretinoin usage to attract attention, particularly from physiatrists, rheumatologists and dermatologists, to this rare adverse effect of isotretinoin.
The EU's Future Role on the Global Stage
Authors: Ruser Alexander , Anheier Helmut K. 
Published: October 2014

AbstractWhat role will the EU play on the global stage? The struggle of some of its members in the current economic crisis, its apparent inability to punch its political weight in international negotiations (e.g. the climate summit in Warsaw in 2013) or play a dominant part in international crisis management (the Arab Spring, Syria) cast doubt on the capabilities of the EU as a global player. In order to regain its strength, the EU has to deal with pressing economic and political questions. It has to provide a credible and feasible road map for economic recovery and social cohesion. At the same time, it has to increase the effectiveness and efficiency of European governance without risking its legitimacy. To preserve its actor capacity, the EU must make sure that the (presently unequally distributed) growth potential stemming from research and development serves the economic recovery of the union as a whole. At the same time, successful efforts to make European governance more efficient must be accompanied by additional safeguard measure to ensure its legitimacy.
Cost‐effectiveness of rapid hepatitisCvirus (HCV) testing and simultaneous rapidHCVandHIVtesting in substance abuse treatment programs
Authors: Schackman Bruce R. , Leff Jared A. , Barter Devra M. , DiLorenzo Madeline A. , Feaster Daniel J. , Metsch Lisa R. , Freedberg Kenneth A. , Linas Benjamin P. 
Published: October 2014

AbstractAimsTo evaluate the cost‐effectiveness of rapid hepatitisCvirus (HCV) and simultaneousHCV/HIVantibody testing in substance abuse treatment programs.DesignWe used a decision analytic model to compare the cost‐effectiveness of noHCVtesting referral or offer, off‐siteHCVtesting referral, on‐site rapidHCVtesting offer and on‐site rapidHCVandHIVtesting offer. Base case inputs included 11% undetected chronicHCV, 0.4% undetectedHIV, 35%HCVco‐infection amongHIV‐infected, 53% linked toHCVcare after testing antibody‐positive and 67% linked toHIVcare. Disease outcomes were estimated from established computer simulation models ofHCV[HepatitisCCost‐Effectiveness (HEP‐CE)] andHIV[Cost‐Effectiveness of PreventingAIDSComplications (CEPAC)].Setting and participantsData on test acceptance and costs were from a national randomized trial ofHIVtesting strategies conducted at 12 substance abuse treatment programs in theUnitedStates.MeasurementsLifetime costs (2011US$) and quality‐adjusted life years (QALYs) discounted at 3% annually; incremental cost‐effectiveness ratios (ICERs).FindingsOn‐site rapidHCVtesting had anICERof $18 300/QALYcompared with no testing, and was more efficient than (dominated) off‐siteHCVtesting referral. On‐site rapidHCVandHIVtesting had anICERof $64 500/QALYcompared with on‐site rapidHCVtesting alone. In one‐ and two‐way sensitivity analyses, theICERof on‐site rapidHCVandHIVtesting remained <$100 000/QALY, except when undetectedHIVprevalence was <0.1% or when we assumed frequentHIVtesting elsewhere. TheICERremained <$100 000/QALYin 91% of probabilistic sensitivity analyses.ConclusionsOn‐site rapid hepatitisCvirus andHIVtesting in substance abuse treatment programs is cost‐effective at a <$100 000/quality‐adjusted life year threshold.
Bottom‐up processes in a declining yellow‐footed rock‐wallaby (Petrogale xanthopus celeris) population
Authors: Sharp Andy , McCallum Hamish 
Published: October 2014

AbstractPopulations of large herbivores are generally considered to be food limited, escaping the regulatory effects of predation through their large body size, migratory behaviour and/or the occurrence of alternate prey species. In the Australian arid and semi‐arid zones, the availability of forage biomass is considered to be the primary driver of fluctuations in kangaroo abundance. However, little is known about the population dynamics of the smaller sympatric macropods. We examined the demographic traits of a large colony of yellow‐footed rock‐wallabies (Petrogale xanthopus celeris), following a 2‐year period of above average rainfall. The population was located within a conservation reserve that was subject to a predator control program around its perimeter and on neighbouring properties. The low predator abundance provided an opportunity to gauge the strength of bottom‐up population processes. During the two years of the study, the population declined in size by 53%, resulting from both the virtual absence of juvenile recruitment and the loss of adult wallabies. Although reproductive output was high, low pouch young and juvenile survival rates resulted in few individuals progressing into the adult population. With minimal recruitment, the rate of population decline (r = 0.77) matched the observed adult survival rate (Φ = 0.76). Despite average rainfall conditions during the study, survival rates across all age‐classes were equivalent to those reported for other rock‐wallaby populations during periods of scarcity. The reduced survival rates were attributed to low levels of forage resources, particularly around the wallabies' refuge sites, suggesting the bottom‐up regulation of the colony at high densities. The data suggest that the colony was at temporarily high abundance, following a rainfall driven pulse of recruitment. Conservation management actions for this species should focus on increasing juvenile survival rates within declining populations, through the control of feral goats (Capra hircus), rabbits (Oryctolagus cuniculus) and red foxes (Vulpes vulpes).
Transcriptomic Profiling of Human Choriodecidua During Term Labor: Inflammation as a Key Driver of Labor
Authors: Stephen Gillian L. , Lui Sylvia , Hamilton Sarah A. , Tower Clare L. , Harris Lynda K. , Stevens Adam , Jones Rebecca L. 
Published: October 2014

ProblemInflammation is a driver of labor in myometrium and cervix; however, the involvement of decidua is poorly defined. We have reported decidual leukocyte infiltration prior to and during labor; the regulators of these inflammatory processes are unknown.Method of studyChoriodecidua RNA obtained after term labor or elective cesarean delivery was applied to Affymetrix GeneChips. Pathway analysis and gene validation were performed.ResultsExtensive inflammatory activation was identified in choriodecidua following labor, predominantly upregulation of genes regulating leukocyte trafficking and cytokine signalling. Genes governing cell fate, tissue remodelling, and translation were also altered. Upregulation of candidate genes (ICAM1, CXCR4, CD44, TLR4, SOCS3, BCL2A, and IDO) was confirmed. NFκB, STAT1&3, HMGB1, and miRNA‐21, miRNA‐46, miRNA‐141, and miRNA‐200 were predicted upstream regulators.ConclusionThis study confirms inflammatory processes are major players in labor events in choriodecidua, as in other gestational tissues. Suppressing uterine inflammation is likely to be critical for arresting premature labor.
Suberoylanilide hydroxamic acid (SAHA) and cladribine synergistically induce apoptosis in NK‐LGL leukaemia
Authors: Sun Xiaoshen , Hasanali Zainul S. , Chen Allshine , Zhang Dianzheng , Liu Xin , Wang Hong‐Gang , Feith David J. , Loughran Thomas P. , Xu Kailin 
Published: October 2014

SummaryNatural killer (NK) large granular lymphocyte (LGL) leukaemia features a clonal proliferation of CD3− NK cells that can be classified into either aggressive or chronic categories. The NKL cell line, derived from an aggressive Asian NK cell leukaemia, and patient samples from chronic NK‐LGL leukaemia were used in our study to probe for synergistic efficacy of the epigenetic drugs vorinostat (SAHA) and cladribine in this disease. We demonstrate that histone deacetylases (HDACs) are over‐expressed in both aggressive and chronic NK leukaemia. Administration of the HDAC inhibitor SAHA reduces class I and II HDAC expression and enhances histone acetylation in leukaemic NK cells. In vitro combination treatment with SAHA and cladribine dose‐dependently exerts synergistic cytotoxic and apoptotic effects on leukaemic NK cells. Expression profiling of apoptotic regulatory genes suggests that both compounds led to caspase‐dependent apoptosis through activation of intrinsic mitochondrial and extrinsic death receptor pathways. Collectively, these data show that combined epigenetic therapy, using HDAC and DNA methyltransferase inhibitors, may be a promising therapeutic approach for NK‐LGL leukaemia.
Low frequency of anti‐D alloimmunization following D+ platelet transfusion: the Anti‐D Alloimmunization after D‐incompatible Platelet Transfusions (ADAPT) study
Authors: Cid Joan , Lozano Miguel , Ziman Alyssa , West Kamille A. , O'Brien Kerry L. , Murphy Michael F. , Wendel Silvano , Vázquez Alejandro , Ortín Xavier , Hervig Tor A. , Delaney Meghan , Flegel Willy A. , Yazer Mark H. ,   the Biomedical Excellence for Safer Transfusion collaborative
Published: October 2014

SummaryThe reported frequency of D alloimmunization in D− recipients after transfusion of D+ platelets varies. This study was designed to determine the frequency of D alloimmunization, previously reported to be an average of 5 ± 2%. A primary anti‐D immune response was defined as the detection of anti‐D ≥ 28 d following the first D+ platelet transfusion. Data were collected on 485 D− recipients of D+ platelets in 11 centres between 2010 and 2012. Their median age was 60 (range 2–100) years. Diagnoses included: haematological (203/485, 42%), oncological (64/485, 13%) and other diseases (218/485, 45%). Only 7/485 (1·44%; 95% CI 0·58–2·97%) recipients had a primary anti‐D response after a median serological follow‐up of 77 d (range: 28–2111). There were no statistically significant differences between the primary anti‐D formers and the other patients, in terms of gender, age, receipt of immunosuppressive therapy, proportion of patients with haematological/oncological diseases, transfusion of whole blood‐derived or apheresis platelets or both, and total number of transfused platelet products. This is the largest study with the longest follow‐up of D alloimmunization following D+ platelet transfusion. The low frequency of D alloimmunization should be considered when deciding whether to administer Rh Immune Globulin to D− males and D− females without childbearing potential after transfusion of D+ platelets.
Why Does Infant Stepping Disappear and Can It Be Stimulated by Optic Flow?
Authors: Barbu‐Roth Marianne , Anderson David I. , Streeter Ryan J. , Combrouze Marie , Park Juana , Schultz Brooke , Campos Joseph J. , Goffinet François , Provasi Joëlle 
Published: October 2014

Two independent experiments (n = 22 and n = 22) showed that 2‐month‐old infants displayed significantly more stepping movements when supported upright in the air than when supported with their feet contacting a surface. Air‐ and surface‐stepping kinematics were quite similar (Experiment 2). In addition, when data were collapsed across both experiments, more air steps and more donkey kicks were seen when infants were exposed to optic flows that specified backward compared to forward translation. The findings challenge the currently accepted heavy legs explanation for the disappearance of stepping at 2 months of age and raise new questions about the visual control of stepping.