bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nano-fabrication of molecular electronic junctions by targeted modification of metal-molecule bonds
Authors: Jafri S. Hassan M. , Löfås Henrik , Blom Tobias , Wallner Andreas , Grigoriev Anton , Ahuja Rajeev , Ottosson Henrik , Leifer Klaus 
Published: September 2015

AbstractReproducibility, stability and the coupling between electrical and molecular properties are central challenges in the field of molecular electronics. The field not only needs devices that fulfill these criteria but they also need to be up-scalable to application size. In this work, few-molecule based electronics devices with reproducible electrical characteristics are demonstrated. Our previously reported 5 nm gold nanoparticles (AuNP) coated with ω-triphenylmethyl (trityl) protected 1,8-octanedithiol molecules are trapped in between sub-20 nm gap spacing gold nanoelectrodes forming AuNP-molecule network. When the trityl groups are removed, reproducible devices and stable Au-thiol junctions are established on both ends of the alkane segment. The resistance of more than 50 devices is reduced by orders of magnitude as well as a reduction of the spread in the resistance histogram is observed. By density functional theory calculations the orders of magnitude decrease in resistance can be explained and supported by TEM observations thus indicating that the resistance changes and strongly improved resistance spread are related to the establishment of reproducible and stable metal-molecule bonds. The same experimental sequence is carried out using 1,6-hexanedithiol functionalized AuNPs. The average resistances as a function of molecular length, demonstrated herein, are comparable to the one found in single molecule devices.
Breathing silicon anodes for durable high-power operations
Authors: Hwang Chihyun , Joo Sehun , Kang Na-Ri , Lee Ungju , Kim Tae-Hee , Jeon Yuju , Kim Jieun , Kim Young-Jin , Kim Ju-Young , Kwak Sang-Kyu , Song Hyun-Kon 
Published: September 2015

AbstractSilicon anode materials have been developed to achieve high capacity lithium ion batteries for operating smart phones and driving electric vehicles for longer time. Serious volume expansion induced by lithiation, which is the main drawback of silicon, has been challenged by multi-faceted approaches. Mechanically rigid and stiff polymers (e.g. alginate and carboxymethyl cellulose) were considered as the good choices of binders for silicon because they grab silicon particles in a tight and rigid way so that pulverization and then break-away of the active mass from electric pathways are suppressed. Contrary to the public wisdom, in this work, we demonstrate that electrochemical performances are secured better by letting silicon electrodes breathe in and out lithium ions with volume change rather than by fixing their dimensions. The breathing electrodes were achieved by using a polysaccharide (pullulan), the conformation of which is modulated from chair to boat during elongation. The conformational transition of pullulan was originated from its α glycosidic linkages while the conventional rigid polysaccharide binders have β linkages.
Correction: A new blue-shifted luciferase from the Brazilian Amydetes fanestratus (Coleoptera: Lampyridae) firefly: molecular evolution and structural/functional properties
Authors: Viviani Vadim R. , Amaral Danilo , Prado Rogilene , Arnoldi Frederico G. C. 
Published: September 2015

Abstract
Correction for ‘A new blue-shifted luciferase from the Brazilian Amydetes fanestratus (Coleoptera: Lampyridae) firefly: molecular evolution and structural/functional properties’ by Vadim R. Viviani et al., Photochem. Photobiol. Sci., 2011, 10, 1879–1886.
Calibration‐spur reduction in current‐steering DAC utilising digital‐and‐analogue hybrid return‐to‐zero (HRZ) method
Authors: Kim W.‐C. , Kim J.‐G. , Ahn K.‐H. , Kim G.‐J. , Park S.‐H. , Ryu S.‐T. 
Published: September 2015

A simple‐but‐efficient calibration‐spur reduction technique is introduced that utilises the digital‐and‐analogue hybrid return‐to‐zero (HRZ) method in a current‐steering DAC employing a round‐robin‐fashioned background current‐source calibration scheme. A simulation with a 12 b 500 MS/s current‐steering DAC showed 9.9 and 7.8 dB improvements in the spur‐free dynamic range and signal‐to‐noise + distortion ratio, respectively, owing to the reduced calibration spur by the proposed HRZ technique.
Transformer inrush mitigation for dynamic voltage restorer using direct flux linkage control
Authors: Gao Shan , Lin Xinchun , Ye Shangjun , Lei He , Kang Yong 
Published: September 2015

Dynamic voltage restorer (DVR) based on transformer‐coupled topology is the most cost‐effective solution to protect consumer from voltage sags. However, an important issue about this topology is the transformer saturation. Magnetic saturation of the transformer will generate large inrush current which may greatly distort the compensation voltage or even trigger the over‐current protection. To prevent the transformer from saturation, this study proposes a novel direct magnetising flux linkage control strategy. Distinguished from existing DVR models which ignored the transformer magnetising branch, this study establishes a comprehensive DVR model by adopting the magnetising flux linkage as a state‐variable. Therefore, by adopting flux linkage feedback, the magnetising flux linkage would be directly controlled. Otherwise, to implement the flux linkage control, this study proposes a robust flux estimation method to carry out the proposed control scheme. Finally, the whole system is verified on a 380 V/10 kVA three‐phase experimental DVR prototype.
Effects of coffee and caffeine anhydrous on strength and sprint performance
Authors: Trexler Eric T. , Smith‐Ryan Abbie E. , Roelofs Erica J. , Hirsch Katie R. , Mock Meredith G. 
Published: September 2015

AbstractCaffeine and coffee are widely used among active individuals to enhance performance. The purpose of the current study was to compare the effects of acute coffee (COF) and caffeine anhydrous (CAF) intake on strength and sprint performance. Fifty‐four resistance‐trained males completed strength testing, consisting of one‐rep max (1RM) and repetitions to fatigue (RTF) at 80% of 1RM for leg press (LP) and bench press (BP). Participants then completed five, 10‐second cycle ergometer sprints separated by one minute of rest. Peak power (PP) and total work (TW) were recorded for each sprint. At least 48 hours later, participants returned and ingested a beverage containing CAF (300 mg flat dose; yielding 3–5 mg/kg bodyweight), COF (8.9 g; 303 mg caffeine), or placebo (PLA; 3.8 g non‐caloric flavouring) 30 minutes before testing. LP 1RM was improved more by COF than CAF (p = .04), but not PLA (p = .99). Significant interactions were not observed for BP 1RM, BP RTF, or LP RTF (p > .05). There were no sprint × treatment interactions for PP or TW (p > .05). 95% confidence intervals revealed a significant improvement in sprint 1 TW for CAF, but not COF or PLA. For PLA, significant reductions were observed in sprint 4 PP, sprint 2 TW, sprint 4 TW, and average TW; significant reductions were not observed with CAF or COF. Neither COF nor CAF improved strength outcomes more than PLA, while both groups attenuated sprint power reductions to a similar degree. Coffee and caffeine anhydrous may be considered suitable pre‐exercise caffeine sources for high‐intensity exercise.
Ontogenetic and Sex-Specific Shifts in the Feeding Habits of the Barndoor Skate
Authors: Schmitt Joseph D. , Gedamke Todd , DuPaul William D. , Musick John A. 
Published: September 2015

Abstract
Diet analysis is critical in understanding the flow of energy within marine food webs and is necessary for trophic ecosystem modeling and subsequent ecosystem-based management recommendations. This study represents the first comprehensive diet description for the Barndoor Skate Dipturus laevis, the largest rajid species found on the continental shelf in the northwestern Atlantic Ocean. Stomach contents were extracted from 273 individual skate caught as bycatch in the commercial scallop fishery on Georges Bank and a total of 31 prey species were identified. The Barndoor Skate feeds primarily upon sand shrimp Crangon septemspinosa, the rock crab Cancer irroratus, the Acadian hermit crab Pagurus acadianus, and teleost fish. Length-specific analysis revealed four significant feeding groups (ANOVA: P &lt; 0.01). Skate &lt; 35 cm TL were specialized feeders foraging solely on caridean shrimp, and as size increased (35–75 cm TL), they began to feed upon rock crab and then the Acadian hermit crab. At lengths ranging from 85 to 105 cm TL, no caridean shrimp were found in the skate's diet and the prevalence of crustaceans decreased. Large skate (&gt;105 cm TL) began to prey heavily upon teleost fish, yet also continued to consume larger crustaceans. Significant sex-specific differences in food habits were also observed in the biggest skate (&gt;105 cm TL): males fed primarily on teleost fish (∼80%); however, females maintained a diet of approximately equal amounts of fish and crustaceans. These sex-specific feeding patterns and differential food niche utilization may be mitigated by sexually dimorphic dentition.
Received November 18, 2014; accepted June 11, 2015
Exploring peptide/MHC detachment processes using hierarchical natural move Monte Carlo
Authors: Knapp Bernhard , Demharter Samuel , Deane Charlotte M. , Minary Peter 
Published: September 2015

Abstract
Motivation: The binding between a peptide and a major histocompatibility complex (MHC) is one of the most important processes for the induction of an adaptive immune response. Many algorithms have been developed to predict peptide/MHC (pMHC) binding. However, no approach has yet been able to give structural insight into how peptides detach from the MHC.
Results: In this study, we used a combination of coarse graining, hierarchical natural move Monte Carlo and stochastic conformational optimization to explore the detachment processes of 32 different peptides from HLA-A*02:01. We performed 100 independent repeats of each stochastic simulation and found that the presence of experimentally known anchor amino acids affects the detachment trajectories of our peptides. Comparison with experimental binding affinity data indicates the reliability of our approach (area under the receiver operating characteristic curve 0.85). We also compared to a 1000 ns molecular dynamics simulation of a non-binding peptide (AAAKTPVIV) and HLA-A*02:01. Even in this simulation, the longest published for pMHC, the peptide does not fully detach. Our approach is orders of magnitude faster and as such allows us to explore pMHC detachment processes in a way not possible with all-atom molecular dynamics simulations.
Availability and implementation: The source code is freely available for download at http://www.cs.ox.ac.uk/mosaics/.
Contact: bernhard.knapp@stats.ox.ac.uk
Supplementary information: Supplementary data are available at Bioinformatics online.
Infertility and reproductive disorders: impact of hormonal and inflammatory mechanisms on pregnancy outcome
Authors: Vannuccini Silvia , Clifton Vicki L. , Fraser Ian S. , Taylor Hugh S. , Critchley Hilary , Giudice Linda C. , Petraglia Felice 
Published: September 2015

Abstract

BACKGROUND
Reproductive disorders and infertility are associated with the risk of obstetric complications and have a negative impact on pregnancy outcome. Affected patients often require assisted reproductive technologies (ART) to conceive, and advanced maternal age is a further confounding factor. The challenge is to dissect causation, correlation and confounders in determining how infertility and reproductive disorders individually or together predispose women to poor pregnancy outcomes.

METHODS
The published literature, to June 2015, was searched using PubMed, summarizing all evidences concerning the perinatal outcome of women with infertility and reproductive disorders and the potential mechanisms that may influence poor pregnancy outcome.

RESULTS
Reproductive disorders (endometriosis, adenomyosis, polycystic ovary syndrome and uterine fibroids) and unexplained infertility share inflammatory pathways, hormonal aberrations, decidual senescence and vascular abnormalities that may impair pregnancy success through common mechanisms. Either in combination or alone, these disorders results in an increased risk of preterm birth, fetal growth restriction, placental pathologies and hypertensive disorders. Systemic hormonal aberrations, and inflammatory and metabolic factors acting on endometrium, myometrium, cervix and placenta are all associated with an aberrant milieu during implantation and pregnancy, thus contributing to the genesis of obstetric complications. Some of these features have been also described in placentas from ART.

CONCLUSIONS
Reproductive disorders are common in women of childbearing age and rarely occur in isolation. Inflammatory, endocrine and metabolic mechanisms associated with these disorders are responsible for an increased incidence of obstetric complications. These patients should be recognized as ‘high risk’ for poor pregnancy outcomes and monitored with specialized follow-up. There is a real need for development of evidence-based recommendations about clinical management and specific obstetric care pathways for the introduction of prompt preventative care measures.
Lidocaine Reduces Acute Postoperative Pain After Supratentorial Tumor Surgery in the PACU: A Secondary Finding From a Randomized, Controlled Trial
Authors: Peng Yuming , Zhang Wei , Kass Ira S. , Han Ruquan 
Published: September 2015

Background:
Perioperative lidocaine infusion has been reported to reduce postoperative pain in patients after abdominal surgery; however, no study has examined lidocaine’s effect on acute postoperative pain after supratentorial tumor surgery.

Methods:
A total of 94 patients scheduled for supratentorial craniotomy were enrolled. Patients received either lidocaine through an intravenous bolus (1.5 mg/kg) after induction followed by infusion at a rate of 2 mg/kg/h until the end of surgery or the same volume of normal saline. Mean arterial blood pressure, heart rate, and bispectral index were recorded at different intraoperative time points. Patients were assessed for pain in the postoperative anesthesia care unit (PACU) by the numeric rating scale (NRS). Other complications including hypertension, tachycardia, dysphoria, and postoperative nausea and vomiting (PONV) were reported.

Results:
There was no significant difference between the normal saline and lidocaine group for mean arterial blood pressure, heart rate, and bispectral index at any time point (P>0.05). There was no significant difference in the incidence of hypertension, tachycardia, dysphoria, and PONV between groups (P>0.05). The incidence of mild pain (NRS between 1 and 3) after surgery in PACU was lower in lidocaine group than that in the normal saline group (P=0.014); the number of patients with an NRS pain score of 0 before leaving the PACU was significantly greater in the lidocaine group. No patient in either group had moderate or severe pain.

Conclusions:
Intraoperative infusion of lidocaine significantly decreases the proportion of patients with acute pain after supratentorial tumor surgery in the PACU.
Real-Time Measurement of Dynamic Changes of Anterior Segment Biometry and Wavefront Aberrations During Accommodation
Authors: Zhu Dexi , Shao Yilei , Peng Yu , Chen Qi , Wang Jianhua , Lu Fan , Shen Meixiao 
Published: September 2015

Objectives:
To analyze the dynamic relationship between ocular geometrical structure and high-order aberrations (HOAs) in teal-time during accommodation of human eye.

Methods:
A custom-built spectral domain optical coherence tomography (OCT) system with high-speed and ultra-long scan depth was used to image the anterior segment, whereas a Shack–Hartmann wavefront sensor was used to detect the whole-eye aberration. A Badal optometer with switched visual targets was integrated with this system to induce 0 and 3.00 D accommodative stimuli. Three young adult subjects were measured and the structural parameters of anterior segment were measured from OCT images and accommodative response and HOAs were calculated and exponentially fitted in real time during the accommodation.

Results:
The dynamic process from nonaccommodation to 3.00 D accommodation results in reduced pupil diameter, shallower anterior chamber depth, and increased crystalline lens thickness. After an accommodative active time, the RMS of the HOAs changes sharply when an accommodative stimulus is introduced and then tends to be stable. The accommodative response time and velocity are characterized by fitted parameters. The individual differences of changing in HOAs between subjects can be explained by the different sign and changing tendency of certain terms of aberration coefficients in form of Zernike polynomials during the accommodation.

Conclusions:
Based on the integrated ocular measurement platform including OCT system and wavefront sensor, our research demonstrated how the morphology of the human anterior segment affect the aberration in real time during accommodation. The dynamic relationship between them helps us to deeply understand the mechanism of accommodation.
Weaning Off Prognosis Factors of Home Parenteral Nutrition for Children With Primary Digestive Disease
Authors: Petit Laetitia‐Marie , Girard Delphine , Ganousse‐Mazeron Solene , Talbotec Cécile , Pigneur Benedicte , Elie Caroline , Corriol Odile , Poisson Catherine , Goulet Olivier , Colomb Virginie 
Published: September 2015

ABSTRACTObjectives:The aim of the present study was to describe the indications for home parenteral nutrition (HPN) in children with primary digestive diseases and to identify factors associated with weaning off.Methods:All the children initially discharged on HPN between January 1, 2000, and December 31, 2009, for chronic intestinal failure (IF) were included. The associations between clinical factors and weaning off of HPN were assessed using a multivariable Cox regression model.Results:Among the 151 children (boys = 58%) included in this study, 98 (65%) presented with short bowel syndrome (SBS), 17 (11%) with digestive neuromuscular disorders, 14 (9%) with mucosal diseases, 13 (9%) with inflammatory bowel disease, and 9 (6%) with other primary digestive diseases. The probability of survival was ~100%. At the end of the follow‐up, the probability for weaning off of HPN was 0.73 (95% confidence interval 0.54–0.84) but varied according to the underlying cause of IF (for example, SBS and inflammatory bowel disease had a better prognosis). The median time until weaning off was 21 months (95% confidence interval 18–38 months). Unfavourable prognostic factors for weaning off of HPN included a bowel remnant of <40 cm, the presence of <50% of the colon, and daily lipid intakes >1.5 g · kg−1 · day−1. Underlying disease was also associated with weaning off.Conclusions:HPN is a safe therapeutic option for children with chronic IF requiring long‐term nutritional management. Prognostic factors for weaning off of HPN were identified, and they highlight the relevance of SBS anatomy and parenteral nutrition caloric intake. The outcome of children on HPN was primarily dependent on the underlying disease.
Glucose modulatesDrosophilalongevity and immunity independent of the microbiota
Authors: Galenza Anthony , Hutchinson Jaclyn , Hazes Bart , Campbell Shelagh D. , Foley Edan 
Published: September 2015

ABSTRACTThe acquisition of nutrients is essential for maintenance of metabolic processes in all organisms. Nutritional imbalance contributes to myriad metabolic disorders that include malnutrition, diabetes, and even cancer. Recently, the importance of macronutrient ratio of food has emerged as a critical factor to determine health outcomes. Here we show that individual modifications to a completely defined diet markedly impact multiple aspects of organism wellbeing inDrosophila melanogaster.Through a longitudinal survey of several diets we demonstrate that increased levels of dietary glucose significantly improve longevity and immunity in adultDrosophila.Our metagenomic studies, show that relative macronutrient levels not only influence the host, but also have a profound impact on microbiota composition. However, we found that elevated dietary glucose extended the lifespan of adult flies even when raised in a germ-free environment. Furthermore, when challenged with a chronic enteric infection, flies fed a diet with added glucose had increased survival times even in the absence of an intact microbiota. Thus, in contrast to known links between the microbiota and animal health, our findings uncover a novel microbiota-independent response to diet that impacts host wellbeing. As dietary responses are highly conserved in animals, we believe our results offer a general understanding of the association between glucose metabolism and animal health.
Glial and neuronal Semaphorin signaling instruct the development of a functional myotopic map forDrosophilawalking
Authors: Syed Durafshan Sakeena , Swetha BM , Reddy O. Venkateswara , Reichert Heinrich , K. VijayRaghavan 
Published: September 2015

SummaryMotoneurons developmentally acquire appropriate cellular architectures that ensure connections with postsynaptic muscles and presynaptic neurons. InDrosophila,leg motoneurons are organized as a myotopic map, where their dendritic domains represent the muscle field. Here we investigate mechanisms underlying development of aspects of this myotopic map, required for walking. A behavioral screen identified roles for Semaphorins (Serna) and Plexins (Plex) in walking behavior. Deciphering this phenotype, we show that PlexA/Sema1a mediates motoneuron axon branching in ways that differ in the proximal femur and distal tibia, based on motoneuronal birth order. Importantly, we show a novel role for glia in positioning dendrites of specific motoneurons; PlexB/Sema2a is required for dendritic positioning of late-born motoneurons but not early-born motoneurons. These findings indicate that communication within motoneurons and between glia and motoneurons, mediated by the combined action of different Plexin/Semaphorin signaling systems, are required for the formation of a functional myotopic map.
Relationship of budget participation conflict and job performance of South Korean managers
Authors: Leach-López Maria A. , Stammerjohan William W. , Lee Eunsuh , Stammerjohan Claire Allison 
Published: September 2015

Purpose– The purpose of this paper is to examine the effect of budget participation conflict (BPC) on job performance and the mediating effect of job satisfaction and job tenure on this relationship in a South Korean setting. BPC is defined as the difference between a manager’s actual budget participation and the same manager’s preferred level of budget participation.Design/methodology/approach– Survey data, analyzed using path analysis, were used to measure the direct effect of BPC on performance, and the indirect effects between BPC and performance running through job satisfaction and job tenure.Findings– Findings suggest that BPC does not directly impact job performance. Overall, this study suggests that BPC has a negative impact on job satisfaction and that job satisfaction in turn can significantly influence job performance. The authors also find some marginal effect of job satisfaction on job tenure, implying that increasing satisfaction can marginally increase job tenure.Research limitations/implications– Limitations of this study are those usually found in cross-sectional survey research.Originality/value– Despite its limitations, this study has both academic and practical implications. The study adds to the job performance literature in an Asian country which has not been widely researched. The study also finds that managers’ job performance and job satisfaction can be improved by minimizing BPC. Future research should study other variables that influence job performance of South Korean managers.