bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Moment-Sum-of-Squares Hierarchy for Robust Polynomial Matrix Inequality Optimization with Sum-of-Squares Convexity
Authors: Guo Feng , Wang Jie 
Published: July 2024

We study a class of polynomial optimization problems with a robust polynomial matrix inequality (PMI) constraint where the uncertainty set itself is also defined by a PMI. These can be viewed as matrix generalizations of semi-infinite polynomial programs because they involve actually infinitely many PMI constraints in general. Under certain sum-of-squares (SOS)-convexity assumptions, we construct a hierarchy of increasingly tight moment-SOS relaxations for solving such problems. Most of the nice features of the moment-SOS hierarchy for the usual polynomial optimization are extended to this more complicated setting. In particular, asymptotic convergence of the hierarchy is guaranteed, and finite convergence can be certified if some flat extension condition holds true. To extract global minimizers, we provide a linear algebra procedure for recovering a finitely atomic matrix-valued measure from truncated matrix-valued moments. As an application, we are able to solve the problem of minimizing the smallest eigenvalue of a polynomial matrix subject to a PMI constraint. If SOS convexity is replaced by convexity, we can still approximate the optimal value as closely as desired by solving a sequence of semidefinite programs and certify global optimality in case that certain flat extension conditions hold true. Finally, an extension to the nonconvexity setting is provided under a rank 1 condition. To obtain the above-mentioned results, techniques from real algebraic geometry, matrix-valued measure theory, and convex optimization are employed. Funding: This work was supported by the National Key Research and Development Program of China [Grant 2023YFA1009401] and the National Natural Science Foundation of China [Grants 11571350 and 12201618].
A nasopalatine duct cyst in an orthodontic patient: a case report
Authors: Hook Hannah , Power Gavin 
Published: July 2024

This case report describes the presentation of a nasopalatine duct cyst in a 27-year-old orthodontic patient. The patient presented with pain in the anterior hard palate and a Class II division 2 occlusion with a complete overbite. The cyst was discovered upon further radiographic investigation. Following discussion at a joint orthognathic clinic, the decision was made to leave the cyst under active monitoring and review the patient clinically and radiographically after 12 months. CPD/Clinical Relevance: Nasopalatine duct cysts are common, therefore awareness of their clinical and radiographic features and treatment options is essential.
Gold nanoparticle-mediated nanosecond laser-induced polystyrene carbonization with luminescent products
Authors: Kudryashov Andrey , Gusev Sergey , Tatarskiy Dmitry , Nadtochenko Victor A. , Bityurin Nikita 
Published: July 2024

A highly soluble Au(I) gold precursor is used to produce a nanocomposite material
consisting of a polystyrene matrix and gold nanoparticles. Irradiation
of such a material with nanosecond laser pulses at the plasmon
resonance wavelength leads to the formation of black spots containing
luminescent products of carbonization. HR TEM analysis and Raman
spectroscopy confirm disordered carbon. A simple model, based on laser
heating of a nanoparticle to a temperature of more than 2000 K
and stabilization of this temperature by the endothermic process of
polystyrene carbonization, fits well with the dependence of the
luminescent signal increment on the laser fluence.
Comparison of intraoperative hemodynamics in classical and single-port adrenalectomy
Authors: Shikhmagomedov Sh. Sh. , Rebrova D. V. , Alekseev M. A. , Krasnov L. M. , Fedorov E. A. , Chinchuk I. K. , Chernikov R. A. , Rusakov V. F. , Sleptsov I. V. , Sablin I. V. , Kuleshov O. V. 
Published: July 2024

BACKGROUND: Pheochromocytoma (PCC) is a tumor from the chromaffin tissue of the adrenal medulla, capable of hyperproduction of catecholamines. An important feature of pheochromocytoma, due to its hormonal activity, is the threat of sudden changes in hemodynamic parameters during surgical treatment. Retroperitoneoscopic access is currently becoming increasingly popular in the surgical treatment of chromaffin tumors of the adrenal glands. In clinical practice, two variants of the mentioned access are used: classic (three-port) and single-port. In this study, the influence of these options of retroperitoneoscopic access on intraoperative hemodynamic control was evaluated.AIM: Comparison of treatment results and intraoperative hemodynamic parameters of patients with adrenal pheochromocytomas operated with single-port and three-port retroperitonescopic access options.MATERIALS AND METHODS: A retrospective single-center cohort study was conducted on a sample of patients initially operated for pheochromocytoma at the Pirogov St. Petersburg State University High Medical Technology Clinic from October 2015 to February 2020 with intraoperative invasive hemodynamic control using PiCCO+ systems.RESULTS: 47 patients were examined, 24 of whom underwent single–port adrenalectomy (included in the first group), 23 — three-port (second group). The average tumor size in the second group was larger (40.12±9.3 and 56.7±21.5, p<0.05), presumably, in this regard, the average duration of surgery was statistically significantly higher (73±21.5 and 111.7±36.1, p<0.05). The body mass index (BMI) of patients in the two groups did not differ statistically significantly. Intraoperatively measured values of maximum and minimum mean systolic and diastolic blood pressure, the number of episodes of increased diastolic blood pressure above 120 mmHg and their duration did not differ statistically in both groups (p>0.05). Episodes of increased systolic blood pressure above 180 mm Hg were more frequent in the second group (p=0.03), but their total duration in the two groups was without significant differences (p>0.05). Intraoperative consumption of antihypertensive drugs during the release of the adrenal gland and vasopressor drugs after compression of the central vein of the adrenal gland were similar. Blood pressure after compression of the central vein in the first and second groups did not differ significantly (p>0.05). No deaths and postoperative complications were registered in both groups.CONCLUSION: Single-port modification of retroperitoneoscopic access with sufficient experience of the anesthesiological team and the operating surgeon does not lead to deterioration of hemodynamic control and operation results, being safe and effective in the surgical treatment of pheochromocytoma.
Gangguan Fonetik pada Penyandang Down Syndrome di SLBN Karanganyar Kabupaten Karanganyar
Authors: Pakerti Falah Ageng , Tiani Riris 
Published: July 2024

Kemampuan anak dalam linguistik dapat diukur dari kemampuanya dalam Psikolinguistik. Tahap pemerolehan bahasa mencakup proses kompetensi dan performasi. Namun, dalam kondisi tertentu ada beberapa kondisi yang menghambat proses dalam Psikolinguistik. Penghambat tersebut disebabkan oleh ketidaknormalan fisik maupun mental, salah satu contoh kelainan Down syndrome. Down syndrome merupakan kelainan yang disebabkan kelebihan kromosom 21 yang mengakibatkan kelainan secara fisik dan mental sehingga menyebabkan kemampuan berbicara terganggu karena alat artikulator yang tidak sempurna. Keterbatasan inilah yang membuat anak penyandang Down syndrome mengalami gangguan berbicara. Penelitian ini bertujuan untuk menguraikan pola-pola penyimpangan fonetik yang terjadi pada anak penyandang Down syndrome. Penelitian ini bersifat kualitatif menggunakan subjek jamak yang terdiri dari tiga orang informan penyandang Down syndrome di SLBN Karanganyar, Kabupaten Karanganyar. Pelafalan yang tidak mampu dilafalkan oleh anak penyandang Down Syndorme konsonan /z/, /sy/,/ny/,/y/,/x/ informan 1, /sy, /ny/, /x/ informan 2, /z/, /sy/, /ny/, dan /x/ informan 3. Penyimpangan fonetik yang terjadi pada pelafalan anak penyandang Down syndrome yang ditemukan yakni penghilangan dan perubahan bunyi.
Exploring the coupling mode of water and fertilizer for improving growth, fruit quality, and yield of the pear in the arid region
Authors: Li Tianle , Gao Zhijian , Bai Xinlu , Yu Sihai , An Shijie , Zheng Qiangqing , Tang Zhihui , Zhi Jinhu 
Published: July 2024

Abstract
Considering the pear in the arid region as the research object, single-factor testing and water–fertilizer coupling testing were conducted. The response of pear tree growth to water, nitrogen, and phosphorus was explored and provided a theoretical basis for efficient water and fertilizer management. Among them, the single-factor test set water, nitrogen, and phosphorus as the three factors, and five levels were set. Screening out W3, W4, N3, N4, P3, and P4 promoted plant nutrient uptake and fruit quality. Eight treatments were set up in the water and fertilizer coupling test: Treatment 1 (T1, W3N3P3), Treatment 2 (T2, W3N3P4), Treatment 3 (T3, W3N4P3), Treatment 4 (T4, W3N4P4), Treatment 5 (T5, W4N3P3), Treatment 6 (T6, W4N3P4), Treatment 7 (T7, W4N4P3), and Treatment 8 (T8, W4N4P4). The results showed that the leaf area index of the T1, T2, T3, and T4 treatments was significantly higher than that of the other treatments at maturity. The yield, single fruit weight, and primary fruit rate were the highest under T3 treatment. The gray correlation degree analysis of fruit quality showed that the T3 treatment had the highest degree of correlation and ranking of each fruit quality index, indicating that the T3 treatment had the highest fruit quality. The yield model showed that irrigation with 6510.06 m3 hm−2, nitrogen fertilizer with 337.5 kg N hm−2, and phosphate fertilizer with 262.5 kg P hm−2 had the best yield. A detailed investigation of pear tree growth and fruit quality showed that the T3 treatment had the best fruit growth and development performance, and the pear fruit quality was the best.
Considerations for applying emerging technologies in paediatric laboratory medicine
Authors: Lang Tim , Geaghan Sharon , Loh Tze Ping , Mak Chloe , Papassotiriou Ioannis , Kyriakopoulou Lianna G. 
Published: July 2024

Abstract
Emerging technology in laboratory medicine can be defined as an analytical method (including biomarkers) or device (software, applications, and algorithms) that by its stage of development, translation into broad routine clinical practice, or geographical adoption and implementation has the potential to add value to clinical diagnostics. Paediatric laboratory medicine itself may be considered an emerging area of specialisation that is established relatively recently following increased appreciation and understanding of the unique physiology and healthcare needs of the children. Through four clinical (neonatal hypoglycaemia, neonatal hyperbilirubinaemia, sickle cell disorder, congenital adrenal hyperplasia) and six technological (microassays, noninvasive testing, alternative matrices, next generation sequencing, exosome analysis, machine learning) illustrations, key takeaways of application of emerging technology for each area are summarised. Additionally, nine key considerations when applying emerging technology in paediatric laboratory medicine setting are discussed.
Fuzzy fractional delay integro-differential equation with the generalized Atangana-Baleanu fractional derivative
Authors: Wang Guotao , Feng Meihua , Zhao Xianghong , Yuan Hualei 
Published: July 2024

Abstract
In this work, we consider a class of fuzzy fractional delay integro-differential equations with the generalized Caputo-type Atangana-Baleanu (ABC) fractional derivative. By using the monotone iterative method, we not only obtain the existence and uniqueness of the solution for the given problem with the initial condition but also give the monotone iteration sequence converging to the unique solution of the problem. Furthermore, we also give the continuous dependence of the unique solution on initial value. Finally, an example is presented to illustrate the main results obtained. The results presented in this study are new and open a new avenue of research for fuzzy fractional delay integro-differential equations with the generalized ABC fractional derivative.
A novel variant of the STAR gene: nonclassical presentation from Turkey
Authors: Aytaç Kaplan Emel Hatun , Gezdirici Alper , Kocabey Sütçü Zümrüt , Gökpinar İli Ezgi 
Published: July 2024

Abstract

Objectives
Lipoid congenital adrenal hyperplasia (LCAH) is a rare autosomal recessive disease caused by mutations in the steroidogenic acute regulatory protein (STAR) gene, expressed in the adrenal and gonadal tissues. In classical LCAH, individuals with 46, XY chromosomes present with a female appearance of the external genitalia due to insufficient androgen production. In the non-classical form, a milder phenotype is observed with male external genitalia. Here, we present a non-classical LCAH diagnosis with a newly identified c.266T>A (p.Ile89Asn) likely pathogenic homozygous variant in a 46, XY infant.

Case presentation
A three-month-and-thirteen-day-old male proband presented with clinical features of cortisol and mineralocorticoid deficiencies. The manifestation of salt-wasting syndrome occurred relatively late, and although the external genitalia appeared male, there was a mild virilization defect. The combination of mild impairment in androgen production and severe salt-wasting syndrome is an intriguing finding in our patient. Peripheral blood samples were obtained from the patient and his family. The newly identified variant, determined by next-generation sequencing analysis, was confirmed by segregation analysis showing carrier status in both parents.

Conclusions
We aim to contribute to the literature by elucidating molecular mechanisms by presenting an atypical presentation and a newly identified variant.
Crystal structure of (S)-1-phenylpropan-1-aminium (S)-(1-phenylpropyl)carbamate C19H26N2O2
Authors: Jiang Qiong-Feng , Ou Guang-Chuan 
Published: July 2024

Abstract
C19H26N2O2, orthorhombic, P212121 (no. 19), a = 5.254(2) Å, b = 12.172(6) Å, c = 29.088(13) Å, V = 1860.2(14) Å3, Z = 4, R

gt
(F) = 0.0509, wR

ref
(F
2) = 0.1345, T = 173 K.
Chinese Crude Oil Futures and Sectoral Stocks: Copula-Based Dependence Structure and Connectedness
Authors: Imran Zulfiqar A. , Ahad Muhammad , Ahmad Mobeen , Hameed Imran 
Published: July 2024

Abstract
China launched its first crude oil futures on 18th March 2018, with the primary objective of introducing its own hedging instrument in China. Our study responds to this objective by investigating the dependence structure based on time-variant and time-invariant copula, connectedness in various market conditions, and hedging effectiveness of oil futures with eleven GICS sectors in China using daily returns data from 19th June 2019 to 24th February 2024. Findings suggest that time-varying copula is a best fit for all the GICS sectors in China except for the Energy. Similarly, the results of time-varying (TVP-VAR) connectedness indicate that the oil futures are the net receiver of shocks in total, short (1–5 days), and long-time (5 to infinity) spillover. The oil futures can better offset portfolio losses during the down market than normal and up markets. Lastly, based on TVP-VAR, the hedging ratio, optimum portfolio weights, and hedge effectiveness are calculated. We find a positive hedge ratio across various pairs of assets, which reduces the assets’ volatility. Moreover, hedge ratios and optimum portfolio weights are non-constant over time. Our results significantly contribute to the scant literature on Chinese crude oil futures and have implications for investors and policymakers.
The crystal and molecular structure of (R)-sirtinol – C26H22N2O2 – a chemo-sensitive enhancer and ligand in metal complexes with important bio-inorganic applications
Authors: Bernal Ivan , Lalancette Roger A. , Hudaihed Ahmad , Kucheryavy Pavel 
Published: July 2024

Abstract
Sirtinol is a known inhibitor of sirtuin proteins – a family of deacetylases involved in the physiology of aging. Its crystalline structure has never been determined except when bound to Fe(III) where it participates in the seven-fold coordination of the metal or to Cu(II) where it acts as a bidentate or tridentate ligand. Herein, we describe the structure of this important molecule, as follows: (a) the prevalent form of the keto-enol tautomerism in the solid state, and (b) in solution. Do they match? If not, how? The crystals of (R)-sirtinol are characterized by a large number of π–π bonded interactions linking molecules in infinite ribbons, which, in turn, are linked by additional π–π interactions of a variety of types, and by hydrogen bonds. In the latter case, we confirm by NMR that the X-ray determined position of an important H atom is on a N atom rather than on an O, which is how the molecule is usually depicted.
Cellulose acetate sheet supported gold nanoparticles for the catalytic reduction of toxic organic pollutants
Authors: Ullah Fahim , Khan Adnan , Gul Kashif , Asiri Abdullah M. , Kamal Tahseen , Ali Nauman 
Published: July 2024

Abstract
Water contamination by toxic organic dyes represents a significant global challenge necessitating effective remediation strategies. Due to their high catalytic activity, considerable attention has been gained to metal-based nanocatalysts. Cellulose acetate sheets supported by gold nanoparticles through a reduction method were synthesized. The composite synthesized material presents a compelling platform for catalytic reduction in the remediation of toxic organic pollutants, ensuring controlled particle size and stability. In this study, the prepared cellulose acetate sheet (CAsheet) was dipped in a 0.001 M aqueous chloroauric acid (HAuCl4) solution and reduced by immersion in a 0.1 M sodium borohydride (NaBH4) aqueous solution. After the successful preparation of virgin cellulose acetate sheet (CAsheet) and gold-supported cellulose acetate sheet (Au-CAsheet) samples were assessed by scanning electron microscopy (SEM), X-ray crystallography (XRD), energy dispersive X-rays spectroscopy (EDX), and Fourier transform infrared spectroscopy (FTIR) analysis. The catalytic reduction reaction of toxic compounds i.e. reduction of 4-nitroaniline (4-NA), Congo red (CR), and reactive yellow (RY-42) by using NaBH4. The catalytic activity of the Au-CAsheet was exhibited by the reaction rate constant (k
app) values 0.3189, 0.1596, and 0.1593 min−1 for CR, 4-NA, and RY-42 respectively. This kind of procedure for Au-CAsheet synthesis may be valid for different applications in catalysis, sensing, and environmental application.
MICROBIOME: Microbiomes in birds: a review of links to health and reproduction
Authors: Ottinger Mary Ann , Mani Shailaja , Krüger Sonja , Coverdale Brent , Willows-Munro Sandi , Combrink Leigh 
Published: July 2024

Microbiomes have emerged as a key component essential for maintaining the health of an organism. Additionally, the roles of microbiomes are multifaceted, some unique to specific body areas and organs while others, particularly the gut microbiome, having broader effects on the entire organism. Comparative literature is emerging that compares microbiomes across mammals and birds. Domestic poultry have been the most extensively studied relative to their role in production agriculture. These data have provided a great deal of information about the effects of diet and nutritional requirements relative to the gut microbiome, productivity, and resilience to diseases. Conversely, limited research has been conducted on wild birds, despite them inhabiting a broad array of ecological niches and environments, providing a rich diversity in their adaptations to different habitats. Migratory birds and raptors are of particular interest. Migratory birds encounter a range of ecosystems and provide a link between allopatric populations. Raptors occupy high positions in the food chain, with potential exposure to biomagnification of environmental contaminants and pathogens. This review overviews our current understanding of the structure and function of avian microbiomes as related to avian health and reproduction in domestic and wild birds, highlighting knowledge gaps in need of further investigation for more effective conservation of rapidly declining avian populations.

Lay summary
Birds are among the most endangered organisms on the planet, vulnerable to many environmental challenges, including disease, loss of habitat, shortage of food resources, and climate-related change. They need to adapt to these challenges to survive and flourish. While the links between the gut microbiome, diet, resistance to infection, and behavior have been well studied in humans, laboratory animals, and domestic or captive birds, comparatively little is known about these associations in wildlife, where diet is expected to be more varied and seasonal. This is especially true for wild bird species. We review the information that is available on the microbiomes of both domestic and wild birds, highlighting knowledge gaps in our understanding of the health and reproduction of wild birds, toward furthering their conservation.
Novel PLCZ1 compound heterozygous mutations indicate gene dosage effect involved in total fertilisation failure after ICSI
Authors: Li Qing , Guo Juncen , Huang Gelin , Wu Nan , Chen Su , Dai Jing , Zhang Xueguang , Zhang Guohui , Zhi Weiwei , Yan Jierui , Zheng Rui , Yan Fei , Yan Zheng , Wu Ling , Wu Sixian , Ji Zhiliang , Zeng Jiuzhi , Lin Ge , Li Bin , Xu Wenming 
Published: July 2024

In brief
PLCZ1 mutations are related to total fertilisation failure (TFF) after intracytoplasmic sperm injection (ICSI), characterised by abnormal oocyte oscillations. The novel PLCZ1 compound heterozygous mutations reported by this study were associated with TFF after ICSI, with one of the mutations indicating a gene dosage effect.

Abstract
Oocyte activation failure is thought to be one of the main factors for total fertilisation failure (TFF) after intracytoplasmic sperm injection (ICSI), which could be induced by abnormal calcium oscillations. Phospholipase C zeta (PLCZ), a sperm factor, is associated with Ca2+ oscillations in mammalian oocytes. To date, some mutations in PLCZ1 (the gene that encodes PLCZ) have been linked to TFF, as demonstrated by the observed reduction in protein levels or activity to induce Ca2+ oscillations. In this study, normozoospermic males whose sperms exhibited TFF after ICSI and their families were recruited. First, mutations in the PLCZ1 sequence were identified by whole exome sequencing and validated using Sanger sequencing. Then, the locations of PLCZ1/PLCZ and the transcript and protein levels in the sperm of the patients were studied. Subsequently, in vitro function analysis and in silico analysis were performed to investigate the function–structure correlation of mutations identified in PLCZ1 using western blotting, immunofluorescence, RT-qPCR, and molecular simulation. Ca2+ oscillations were detected after cRNA microinjection into MII mouse oocytes to investigate calcium oscillations induced by abnormal PLCZ. Five variants with compound heterozygosity were identified, consisting of five new mutations and three previously reported mutations distributed across the main domains of PLCZ, except the EF hands domain. The transcript and protein levels decreased to varying degrees among all detected mutations in PLCZ1 when transfected in HEK293T cells. Among these, mutations in M138V and R391* of PLCZ were unable to trigger typical Ca2+ oscillations. In case 5, aberrant localisation of PLCZ in the sperm head and an increased expression of PLCZ in the sperm were observed. In conclusion, this study enhances the potential for genetic diagnosis of TFF in clinics and elucidates the possible relationship between the function and structure of PLCZ in novel mutations.