bluuebunny/crossref_metadata_2025_split huggingface dataset:
Frequency and Distribution of Dental Anomalies in Iran: A Radiographic Survey
Authors: Tofangchiha Maryam , Azimi Somayyeh , Neirizi Masoud 
Published: June 2013

ABSTRACT

Aim
Many epidemiological studies have been performed around the world in order to determine the frequency of different types of dental anomalies. There are regional and ethnic variations in the prevalence of dental anomalies.
To determine the prevalence of developmental and acquired dental anomalies in Iran, study was done from 2011 to 2012.

Materials and methods
A total of 1,000 digital panoramic radiographs of patient were evaluated which consisted of 424 (42/4%) male and 576 (57/6%) female. Data were analyzed by Chi-square and Fisher exact tests.

Results
Wisdom tooth impaction was the most prevalent anomaly (41.4% in females and 36% in males) followed by missing (8.7% male, 7/3% female), microdontia (3.2%), dilacerations (2.2%), macrodontia (1%), supernumerary teeth (0.8%), fusion and taurodontism (0.2%). A case of bilateral second mandibular molar impaction was observed. Germination, transposition and concrescence were not observed. Among the acquired anomalies, hypercementosis (0.6%) and internal resorption (0.4%) were the most prevalent respectively. External resorption was not observed.

Conclusion
Comparison of these results with those of other studies, showed that the frequency of these disorders were different in countries and communities around the world. Knowledge about these anomalies may facilitate the endodontic, prosthodontics, periodontics and surgical management of such teeth.

How to cite this article
Tofangchiha M, Azimi S, Neirizi M. Frequency and Distribution of Dental Anomalies in Iran: A Radiographic Survey. Int J Experiment Dent Sci 2013;2(1): 14-17.
Use of Lasers in Nonsurgical Periodontal Therapy
Authors: Kulkarni Varun , Uttamani Juhi , Shaikh Imaad 
Published: June 2013

ABSTRACT
The use of dental lasers for treatment of periodontal diseases has been the area of interest in the recent years. Current evidence indicates that the use of lasers for the treatment of adult chronic periodontitis—either used solely or as an adjunct to traditional scaling and root planning therapy—offers minimal benefit. This article which is a peer review of various articles provides a brief explanation of the mechanism behind soft tissue lasers. The use of laser therapy in addition to traditional nonsurgical periodontal treatment in the management of periodontal diseases is reviewed. Lasers have been applied for hard and soft tissue debridement, as also for the bacterial load reduction from the periodontal pocket. Although, subgingival application of few of them during nonsurgical periodontal therapy can result in undesired outcomes, even when using manufacturer-recommended parameters. Over the past 20 years the research conducted regarding the clinical application of lasers is very limited. This article tries to fill in the void by reviewing the current and potential application of laser therapy. It has in turn proven to be a promising field in nonsurgical periodontal treatment of diseases.

How to cite this article
Uttamani J, Shaikh I, Kulkarni V. Use of Lasers in Nonsurgical Periodontal Therapy. Int J Experiment Dent Sci 2013;2(1):29-32.
Occupational Hazards in Modern Dentistry
Authors: Shaik Mohammed Asif , Mohammed Naheeda Shaik 
Published: June 2013

ABSTRACTDentists, as well as other dental personnel are constantly exposed to a number of specific occupational hazards. These cause the appearance of various ailments, specific to the profession, which develop and intensify with years. Despite numerous technical advances in recent years, many occupational health problems still persist in modern dentistry. These include percutaneous exposure incidents (PEI), exposure to infectious diseases, radiation, dental materials, musculoskeletal disorders (MSD), dermatitis, respiratory disorders, eye injuries and psychological problems. PEI remains a particular concern, as there is an almost constant risk of exposure to serious infectious agents. Aside from biological hazards, dentists continue to suffer a high prevalence of MSD, especially of the back, neck and shoulders. Awareness regarding these occupational hazards and implementation of preventive strategies can provide a safe working environment for all the dental personnel. There is also a need for continuing dental education programs in dentistry so that dentists can update themselves with the latest and newer techniques and materials.How to cite this articleMohammed NS, Shaik MA. Occupational Hazards in Modern Dentistry. Int J Experiment Dent Sci 2013;2(1):33-40.
Investigating the Effectiveness of Full-Time Wrist Splinting and Education in the Treatment of Carpal Tunnel Syndrome: A Randomized Controlled Trial
Authors: Hall Barbara , Lee Hoe C. , Fitzgerald Helen , Byrne Brent , Barton Annette , Lee Andy H. 
Published: June 2013

Abstract
This study investigated the effects of wearing a wrist support splint for 8 wk and receiving a formal education program on patients with carpal tunnel syndrome (CTS), as well as factors associated with patients’ desire to seek surgical intervention. Participants were recruited from a hospital surgical wait list and randomly assigned to an intervention group (n = 30) or a control group (n = 24). Significant improvements in measures of symptom severity and functional status over the duration of the study appeared in the intervention group but not in the control group. Logistic regression for the intervention group showed that symptom severity (odds ratio [OR] = 1.53, 95% confidence interval [CI] [1.20–1.93]), functional deficits (OR = 1.31, 95% CI [1.08–1.57]), pain score (OR = 1.25, 95% CI [1.11–1.61]), and symptom duration (OR = 1.11, 95% CI [1.01–1.24]) were positively associated with the desire to seek surgical intervention. This conservative CTS treatment program conducted by occupational therapists can improve symptoms and hand function in CTS patients.
Evidence for the Effectiveness of Different Service Delivery Models in Early Intervention Services
Authors: Kingsley Karrie , Mailloux Zoe 
Published: June 2013

Abstract
Consideration of the evidence for all aspects of service delivery is a growing relevant concern of occupational therapists, including those providing early intervention to children and families. We conducted a review of the literature to uncover what evidence existed for determining the effectiveness of different service delivery models and methods used to improve occupational performance for children and families who receive early intervention services. Through a comprehensive search, we reviewed and synthesized studies, finding common themes of family-centered and routine-based approaches, service setting, and the inclusion of parent participation and training. Families consistently reported positive perceptions of family-centered and routine-based approaches. Parent participation and training resulted in positive outcomes. No specific setting or method of service delivery was identified as clearly most effective, with most studies reporting combined approaches and environments for interventions.
Effects of Visual Rehabilitation on a Child With Severe Visual Impairment
Authors: Tsai Li-Ting , Meng Ling-Fu , Wu Wei-Chi , Jang Yuh , Su Yu-Chin 
Published: June 2013

Abstract
We examined the effects of visual rehabilitation, including a chromatic luminance discrimination program and a fixation training program, on a 6-yr-old boy with severe visual impairment. Single-subject ABA and AB designs were used. The programs were conducted 2×/wk and included 6 to 7 sessions for the baseline phase and 10 to 11 sessions for the intervention phase. Play was integrated into the visual training programs. Goggle visual evoked potential (VEP) testing was used to evaluate neural activity in the primary visual cortex. Correct responses increased and response times were shortened after training in luminance discrimination. The total and maximum fixation time also improved, as did P100 latency and amplitude of VEPs. While walking, the boy was able to detect obstacles he had not noticed before training. The results indicate the value of visual training and the possibility of brain plasticity in a child with severe visual impairment.
Mobile Media Content Exposure and Toddlers’ Responses to Attention Prompts and Behavioral Requests
Authors: Webb Sara Jane , Howard Waylon , Garrison Michelle , Corrigan Sarah , Quinata Shayeleen , Taylor Lani , Christakis Dimitri A. 
Published: July 2024

ImportanceWith personalized touch-screen tablets, young children can choose content and engage in play-like activities. However, tablets may also reduce shared engagement as the action of viewing or touching the screen is often not visible to nearby adults. This may impact communicative gazing and pointing, which is critical to the formation of shared awareness and in turn supports language development.ObjectiveTo assess the association of tablet media content with toddlers’ responses to joint attention prompts and behavioral requests.Design, Setting, and ParticipantsThis cohort study took place at a behavioral research laboratory and included toddlers who were aged 18 to 32 months with neurotypical development who were recruited from a volunteer and community sample. Toddlers engaged with a real toy or 3 different types of tablet content (ie, viewing video of toy play, playing with a digital toy, or playing a commercial game) while an experimenter delivered joint attention prompts. Data were acquired from June 2021 November XX 2022, and data analysis occurred from January 2023 to May 2024.Main Outcomes and MeasuresMain outcomes included child response to joint attention (number of prompts with joint attention response per number of prompts delivered) and child response to behavioral request (ie, the prompt on which the child responded to the behavioral request). Measures included crossed random effects, Wald tests, and likelihood ratio tests.ResultsIn this study, 63 toddlers were enrolled, and data from 62 were included (31 female [49%]; mean [SD] age, 26.1 [3.4] months; median [IQR] age, 25.0 [18.6-32.6] months). When toddlers were playing a commercial game on a tablet, they responded to fewer joint attention prompts (crossed random effects model, −0.15; 95% CI, −0.24 to −0.06 prompts) and male toddlers took longer to acknowledge a behavioral request (interaction of content and sex, −0.75; 95% CI, −1.36 to −0.17). The negative impact of the tablet game was larger as child age increased (τ = −2.30; 95% CI, −0.05 to 0; P = .03). Greater media use at home was associated with decreased responding to joint attention prompts during the tablet game (ρ = −0.47; P &amp;lt; .001), while better language skills were associated with more joint attention during play with a real toy (ρ = 0.31; P = .02).Conclusions and RelevanceIn this cohort study, a touch-screen tablet game was associated with decreased joint attention among toddlers and they were less likely to respond to a behavioral request. In a laboratory setting, it was difficult for toddlers to engage in social-communicative interactions with adults when using a tablet media device.
Health Care Costs After Genome-Wide Sequencing for Children With Rare Diseases in England and Canada
Authors: Weymann Deirdre , Buckell John , Fahr Patrick , Loewen Rosalie , Ehman Morgan , Pollard Samantha , Friedman Jan M. , Stockler-Ipsiroglu Sylvia , Elliott Alison M. , Wordsworth Sarah , Buchanan James , Regier Dean A. 
Published: July 2024

ImportanceEtiologic diagnoses for rare diseases can involve a diagnostic odyssey, with repeated health care interactions and inconclusive diagnostics. Prior studies reported cost savings associated with genome-wide sequencing (GWS) compared with cytogenetic or molecular testing through rapid genetic diagnosis, but there is limited evidence on whether diagnosis from GWS is associated with reduced health care costs.ObjectiveTo measure changes in health care costs after diagnosis from GWS for Canadian and English children with suspected rare diseases.Design, Setting, and ParticipantsThis cohort study was a quasiexperimental retrospective analysis across 3 distinct English and Canadian cohorts, completed in 2023. Mixed-effects generalized linear regression was used to estimate associations between GWS and costs in the 2 years before and after GWS. Difference-in-differences regression was used to estimate associations of genetic diagnosis and costs. Costs are in 2019 US dollars. GWS was conducted in a research setting (Genomics England 100 000 Genomes Project [100KGP] and Clinical Assessment of the Utility of Sequencing and Evaluation as a Service [CAUSES] Research Clinic) or clinical outpatient setting (publicly reimbursed GWS in British Columbia [BC], Canada). Participants were children with developmental disorders, seizure disorders, or both undergoing GWS between 2014 and 2019. Data were analyzed from April 2021 to September 2023.ExposuresGWS and genetic diagnosis.Main Outcomes and MeasuresAnnual health care costs and diagnostic costs per child.ResultsStudy cohorts included 7775 patients in 100KGP, among whom 788 children had epilepsy (mean [SD] age at GWS, 11.6 [11.1] years; 400 female [50.8%]) and 6987 children had an intellectual disability (mean [SD] age at GWS, 8.2 [8.4] years; 2750 female [39.4%]); 77 patients in CAUSES (mean [SD] age at GWS, 8.5 [4.4] years; 33 female [42.9%]); and 118 publicly reimbursed GWS recipients from BC (mean [SD] age at GWS, 5.5 [5.2] years; 58 female [49.2%]). GWS diagnostic yield was 143 children (18.1%) for those with epilepsy and 1323 children (18.9%) for those with an intellectual disability in 100KGP, 47 children (39.8%) in the BC publicly reimbursed setting, and 42 children (54.5%) in CAUSES. Mean annual per-patient spending over the study period was $5283 (95% CI, $5121-$5427) for epilepsy and $3373 (95% CI, $3322-$3424) for intellectual disability in the 100KGP, $724 (95% CI, $563-$886) in CAUSES, and $1573 (95% CI, $1372-$1773) in the BC reimbursed setting. Receiving a genetic diagnosis from GWS was not associated with changed costs in any cohort.Conclusions and RelevanceIn this study, receiving a genetic diagnosis was not associated with cost savings. This finding suggests that patient benefit and cost-effectiveness should instead drive GWS implementation.
Heterogeneity in Antidepressant Treatment and Major Depressive Disorder Outcomes Among Clinicians
Authors: Rathnam Sarah , Hart Kamber L. , Sharma Abhishek , Verhaak Pilar F. , McCoy Thomas H. , Doshi-Velez Finale , Perlis Roy H. 
Published: July 2024

ImportanceWhile abundant work has examined patient-level differences in antidepressant treatment outcomes, little is known about the extent of clinician-level differences. Understanding these differences may be important in the development of risk models, precision treatment strategies, and more efficient systems of care.ObjectiveTo characterize differences between outpatient clinicians in treatment selection and outcomes for their patients diagnosed with major depressive disorder across academic medical centers, community hospitals, and affiliated clinics.Design, Setting, and ParticipantsThis was a longitudinal cohort study using data derived from electronic health records at 2 large academic medical centers and 6 community hospitals, and their affiliated outpatient networks, in eastern Massachusetts. Participants were deidentified clinicians who billed at least 10 International Classification of Diseases, Ninth Revision (ICD-9) or Tenth Revision (ICD-10) diagnoses of major depressive disorder per year between 2008 and 2022. Data analysis occurred between September 2023 and January 2024.Main Outcomes and MeasuresHeterogeneity of prescribing, defined as the number of distinct antidepressants accounting for 75% of prescriptions by a given clinician; proportion of patients who did not return for follow-up after an index prescription; and proportion of patients receiving stable, ongoing antidepressant treatment.ResultsAmong 11 934 clinicians treating major depressive disorder, unsupervised learning identified 10 distinct clusters on the basis of ICD codes, corresponding to outpatient psychiatry as well as oncology, obstetrics, and primary care. Between these clusters, substantial variability was identified in the proportion of selective serotonin reuptake inhibitors, selective norepinephrine reuptake inhibitors, and tricyclic antidepressants prescribed, as well as in the number of distinct antidepressants prescribed. Variability was also detected between clinician clusters in loss to follow-up and achievement of stable treatment, with the former ranging from 27% to 69% and the latter from 22% to 42%. Clinician clusters were significantly associated with treatment outcomes.Conclusions and RelevanceGroups of clinicians treating individuals diagnosed with major depressive disorder exhibit marked differences in prescribing patterns as well as longitudinal patient outcomes defined by electronic health records. Incorporating these group identifiers yielded similar prediction to more complex models incorporating individual codes, suggesting the importance of considering treatment context in efforts at risk stratification.
Accelerated Intermittent Theta-Burst Stimulation and Treatment-Refractory Bipolar Depression
Authors: Sheline Yvette I. , Makhoul Walid , Batzdorf Alexandra S. , Nitchie Frederick J. , Lynch Kevin G. , Cash Robin , Balderston Nicholas L. 
Published: July 2024

ImportanceBipolar disorder (BD) is chronic and disabling, with depression accounting for the majority of time with illness. Recent research demonstrated a transformative advance in the clinical efficacy of transcranial magnetic stimulation for treatment-resistant major depressive disorder (MDD) using an accelerated schedule of intermittent theta-burst stimulation (aiTBS), but the effectiveness of this treatment for treatment-refractory BD is unknown.ObjectiveTo evaluate the effectiveness of aiTBS for treatment-refractory BD.Design, Setting, and ParticipantsThis randomized clinical trial, conducted from March 2022 to February 2024, included individuals with treatment-resistant BD with moderate to severe depressive episodes referred from the Penn Bipolar outpatient clinic. Included patients had 2 or more prior failed antidepressant trials by Antidepressant Treatment History Form criteria and no other primary psychiatric diagnosis, were receiving a mood stabilizer for 4 or more weeks, and had a Montgomery-Åsberg Depression Rating Scale (MADRS) score of 20 or higher.InterventionPrior to treatment, resting-state functional magnetic resonance imaging was used to compute personalized left dorsolateral prefrontal cortex target by connectivity to subgenual anterior cingulate cortex. Patients were randomized 1:1 to 10 sessions per day of imaging-guided active or sham aiTBS for 5 days with 1 session per hour at 90% resting motor threshold for 90 000 pulses total.Main Outcome and MeasuresThe main outcome was repeated MADRS scores before and after treatment.ResultsA total of 24 participants (12 [50%] female; 12 [50%] male; mean [SD] age, 43.3 [16.9] years) were randomized to active (n = 12) or sham (n = 12) aiTBS. All participants completed treatment and 1-month follow-up. MADRS scores were significantly lower in the active group (mean [SD], 30.4 [4.8] at baseline; 10.5 [6.7] after treatment) than in the sham group (28.0 [5.4] at baseline; 25.3 [6.7] after treatment) at treatment end (estimated difference, –14.75; 95% CI, –19.73 to –9.77; P &amp;lt; .001; Cohen d, –2.19).Conclusion and RelevanceIn this randomized clinical trial, aiTBS was more effective than sham stimulation for depressive symptom reduction in patients with treatment-resistant BD. Further trials are needed to determine aiTBS durability and to compare with other treatments.Trial RegistrationClinicalTrials.gov Identifier: NCT05228457
A mechanism of customizing learning programs for older adults’ lifelong learning
Authors: Suto Hidetsugu , Wang Qianran 
Published: July 2024

AbstractJapan, like many countries, is facing problems with an aging society, and lifelong learning is becoming more and more important. To provide older adults with the opportunity to enroll in lifelong learning programs, it is essential to offer suitable programs. However, designing learning programs for older adults is not easy because they may have various physical and mental conditions. To approach the problem, the authors have proposed a mechanism for personalizing learning programs for older adults. The basic ideas of the mechanism are: (1) omitting unessential steps and (2) suggesting collaboration with others. In this paper, the algorithm and the data structures of the mechanism are explained, and results of experiments are shown.
Highly Conductive Double‐Wall Carbon Nanotube Fibers Produced by Dry‐Jet Wet Spinning
Authors: Wang Hao‐Zike , Jiao Xin‐Yu , Gao Zhao‐Qing , Hou Peng‐Xiang , Xu Le‐Le , Shi Chao , Liang Yan , Wang Yun‐Peng , Liu Chang 
Published: July 2024

AbstractCarbon nanotube fibers (CNTFs) are considered an ideal candidate as next‐generation conducting wires due to their high conductivity and low density. However, the orientation and compaction of the nanotubes in a CNTF need to be further improved to achieve even higher conductivity and ampacity. Here the fabrication of double‐wall CNTFs (DWCNTFs) is reported by a dry‐jet wet spinning method, which significantly improves the orientation and compaction of the carbon nanotubes (CNTs). As a result, the obtained DWCNTFs have a record high electrical conductivity of 1.1 × 107 S m−1 and ampacity of 8.0 × 108 A m−2. The fibers also have a high tensile strength of 1.65 GPa and a toughness of 130.9 MJ m−3, among the highest for wet‐spun CNTFs. The DWCNTFs preserve their integrity and conductivity after more than 5000 bending cycles. Theoretical calculations indicate that in a dry‐jet wet‐spinning process, gravity promotes the orientation of the CNTs along the axial direction of the fiber.
Harnessing Liquid Metals with In Situ Polymerized Electrolyte for Anode‐Free Lithium Metal Batteries
Authors: Nguyen Minh Hai , Kim Dohun , Kim Byung‐Kook , Park Sangbaek 
Published: July 2024

AbstractTo enhance safety and energy density in conventional Li‐ion batteries, anode‐free or zero‐lithium configurations using only a current collector (CC) in the anode have emerged. However, challenges including rapid Li dendrite growth, low Coulombic efficiency, safety concerns, and thickness issues hinder the practical use of anode‐free batteries (AFBs) with liquid electrolytes (LEs) or solid electrolytes (SEs). Herein, potential AFBs using an anode current collector coated with a liquid metal (LM)@C nanocomposite with an in situ polymerized electrolyte (PE) are reported. Interestingly, LM nanoparticles added to the composite layer on CC play a crucial role in promoting uniform Li plating/stripping behavior through a self‐healing mechanism, along with reversible liquid–solid–liquid phase transitions caused by alloying and de‐alloying of Li and LMs. Furthermore, incorporating in situ polymerized electrolytes stabilizes LMs by preventing the agglomeration of LM nanoparticles, resulting in significantly improved cell performance compared to other conventional LEs. A systematical model study with ex situ analysis unveils the synergetic effects between LMs and PE, along with elucidating the mechanism of in situ polymerization and Li‐LMs reactions. The investigation contributes valuable insights for future studies on practical applications of AFBs using polymer electrolytes and composite interlayers.