bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fate and transport of fragmented and spherical microplastics in saturated gravel and quartz sand
Authors: Ameen Ahmad , Stevenson Margaret E. , Kirschner Alexander K. T. , Jakwerth Stefan , Derx Julia , Blaschke Alfred P. 
Published: August 2024

AbstractMicroplastics in urban runoff undergo rapid fragmentation and accumulate in the soil, potentially endangering shallow groundwater. To improve the understanding of microplastic transport in groundwater, column experiments were performed to compare the transport behavior of fragmented microplastics (FMPs ∼1‐µm diameter) and spherical microplastics (SMPs ∼1‐, 10‐, and 20‐µm diameter) in natural gravel (medium and fine) and quartz sand (coarse and medium). Polystyrene microspheres were physically abraded with glass beads to mimic the rapid fragmentation process. The experiments were conducted at a constant flow rate of 1.50 m day−1 by injecting two pore volumes of SMPs and FMPs. Key findings indicate that SMPs showed higher breakthrough, compared to FMPs in natural gravel, possibly due to size exclusion of the larger SMPs. Interestingly, FMPs exhibited higher breakthrough in quartz sand, likely due to tumbling and their tendency to align with flow paths, while both sizes (larger and smaller relative to FMPs) of SMPs exhibited higher removal in quartz sand. Therefore, an effect due to shape and size was observed.
Internet development and green economic efficiency in China: A new perspective of government's dual goal constraints and citizens' green lifestyle
Authors: Quan Tianshu , Yang Bin , Quan Tianli , Zhang Hui , Yu Yi 
Published: August 2024

AbstractThe rapid development of the information and communication technologies (ITCs) and the internet is deeply embedded in all aspects of economic life. With its high economic efficiency and significant green attributes, digitalization provides opportunities for promoting a green economy. However, the effects of digitalization and internet development on China's green economic efficiency are understudied. There is also a gap in research on how digitalization and internet development influence Chinese citizens to choose a green lifestyle from the consumer perspective. This article aims to enrich the research in this field by exploring the effects of internet development on green economic efficiency in China. The article further analyses how digitalization and internet development can encourage citizens to choose a green lifestyle. Drawing on panel data from 257 cities in China spanning the period from 2012 to 2020, this article utilizes the entropy method and the SBM‐GML model to assess the correlation between internet development and green economy efficiency. We also employ the basic regression model, system GMM model, mediation effect model and adjustment model to study the impact of internet development on urban green economic efficiency. The study found that internet development and green economic efficiency face constraints that are inherent in the government's dual economic growth and environmental goals and targets. We also found that digitalization and internet development can promote citizens' adoption of green lifestyles through the fostering of citizen environmental concern and green consumption habits. Further analysis shows that internet development has a more pronounced effect on green economic efficiency in eastern cities, large cities, non‐resource‐based cities and cities with higher economic development. These findings provide useful references for developing countries that promote urban green economic efficiency through digitalization and internet development.
Clinical glycoprotein mass spectrometry: The future of disease detection and monitoring
Authors: Marrero Roche Daniel E. , Chandler Kevin Brown 
Published: August 2024

AbstractProtein glycosylation is the co‐ and/or post‐translational modification of proteins with oligosaccharides (glycans). This process is not template based and can introduce a heterogeneous set of glycan modifications onto substrate proteins. Glycan structures preserve biomolecular information from the cell, with glycoproteins from different cell types and tissues displaying distinct patterns of glycosylation. Several decades of research have revealed that glycan structures also differ between normal physiology and disease. This suggests that the information stored in glycoproteins and glycans can be utilized for disease diagnosis and monitoring. Methods that enable sensitive and site‐specific measurement of protein glycosylation in clinical settings, such as nano‐flow liquid chromatography tandem mass spectrometry, are therefore essential. The purpose of this perspective is to discuss recent advances in mass spectrometry and the potential of these advances to facilitate the detection and monitoring of disease‐specific glycoprotein glycoforms. Glycoproteomics, the system‐wide characterization of glycoprotein identity inclusive of site‐specific characterization of carbohydrate modifications on proteins, and glycomics, the characterization of glycan structures, will be discussed in this context. Quantitative measurement of glycopeptide markers via parallel reaction monitoring is highlighted. The development of promising glycopeptide markers for autoimmune disease, liver disease, and liver cancer is discussed. Synthetic glycopeptide standards, ambient ionization mass spectrometry, and consideration of glyco‐biomarkers in two‐ and three‐dimensional space within tissue will be critical to the advancement of this field. The authors envision a future in which glycoprotein mass spectrometry workflows will be integrated into clinical settings, to aid in the rapid diagnosis and monitoring of disease.
Managing career plateaus for mid‐career professionals: A process‐driven practice intervention using life‐design counseling
Authors: Unnikrishnan Deepa , Rajeev Priya Nair 
Published: August 2024

AbstractThis qualitative study explores the impact of life‐design counseling (LDC) on mid‐career professionals facing career plateauing. Seven mid‐career professionals underwent counselling sessions focused on overcoming barriers, evaluating career beliefs, and exploring options. Thematic analysis delves into their experiences, attitudes, and unresolved mid‐career dilemmas. Results indicate a shift from problem‐focused to solution‐based thinking. A two‐wave longitudinal study spanning 4 years confirms counseling's effectiveness in assisting individuals in making crucial career decisions, guiding positive career redirection amidst mid‐career plateauing. Our study specifically explored and analyzed the practical application of LDC intervention in the real‐world counseling scenario for overcoming career plateauing.
A matter of research integrity: The reporting of statistical software used in studies published in nursing journals in 2023
Authors: Hedlund Åsa , Lindberg Magnus 
Published: August 2024

AbstractThe field of nursing has consistently upheld a strong sense of ethical awareness, which can be assumed to be reflected in the performance of nursing research. Adhering to sound research principles involves prioritizing research integrity. This entails being clear and open in detailing the methods used, allowing others to have confidence in both the methods and the resulting outcomes. This methodological review aimed to provide an overview of how statistical software programs have been reported in nursing studies. We screened articles published in the year 2023 in the five top‐ranking and the five bottom‐ranking nursing journals and found 311 that were eligible for this review; that is, quantitative/mixed‐methods/meta‐analyses. The most commonly used statistical software programs in these articles was IBM SPSS Statistics, followed by R. However, one out of 10 studies did not report the software used. Among those that reported the software, the software version was not always reported. Our findings suggest that there is insufficient reporting on the statistical software used for analysing quantitative data in nursing journal publications. From a perspective of maintaining research integrity, this presents an issue, as it jeopardizes transparency, sincerity, and, consequently, the ability to replicate methods and have confidence in the results.
Hot corrosion behavior of Mo–Si–Ti alloys
Authors: Beck Katharina , König Till , Senvardarli Ekin , Hinrichs Frauke , Heilmaier Martin , Galetz Mathias C. 
Published: August 2024

AbstractThe hot corrosion behavior of two ternary Mo–Si–Ti alloys (eutectic Mo–20.0Si–52.8Ti (at.%) and eutectoid Mo–21.0Si–34.0Ti (at.%)) was investigated at C and C for up to 100 h. Both Mo‐based alloys evidenced a hot corrosion attack, resulting in a uniform attack of the substrate surface. The higher Ti content of the eutectic alloy significantly reduced the formation of solid and volatile Mo oxides compared with the eutectoid alloy. After 24 h at C, the corrosion products formed on the eutectic alloy were only one‐tenth the thickness of the layers formed on the eutectoid alloy. The corrosion products were examined with optical and electron microscopy. Semiquantitative electron probe micro analysis and X‐ray diffraction measurements were used to identify the formed phases. The underlying corrosion mechanisms comprising not only hot corrosion‐induced fluxing but also oxidation‐induced pesting are discussed in detail.
The determination of the price of capital goods: A differential game approach
Authors: Guerrazzi Marco , Candido Giuseppe 
Published: August 2024

AbstractIn this paper, we address the determinants of the price of newly installed productive capacity. Specifically, we develop a differential game in which a competitive producer of consumption goods deals with a seller of capital goods endowed with market power. From a theoretical perspective, we demonstrate that an open‐loop Stackelberg equilibrium requires the producer of consumption goods to be more impatient than the seller of capital goods. Thereafter, we show that our theoretical setting can replicate the countercyclical pattern of the relative price of capital goods as well as its negative relationship with the investment–output ratio.
The prognostic value of microRNA‐200 family expression in digestive system tumors: A meta‐analysis and validation
Authors: Wu Xiaoshuang , Heng Jinghua , Li Mengxiang , Deng Danxia , Wu Bingli , Wang Muting , Li Sanqiang , Gao Shegan , Qi Yijun , Li Enmin 
Published: August 2024

AbstractThe relevance of miR‐200 family in the prognosis of digestive system tumors remains controversial. Through a systematic review of the pertinent literature using online databases including PubMed, EMBASE, The Cochrane Library, and Web of Science, our pooled‐analysis revealed that miR‐200 family downregulation was significantly correlated with poor overall survival (OS, hazard ratio [HR] > 1) and disease‐free survival (HR > 1) in digestive malignancies. Consistently, subgroup analyzes of various organ tissues, univariate analysis, gastric cancer, pancreatic cancer, and patients of American descent revealed the hazardous effects of miR‐200 family downregulation. In contrast, low miR‐200 family expression in blood samples predicted favorable OS (HR < 1). Moreover, lower expression levels of miR‐200c‐5p and miR‐429 were validated in esophageal squamous cell carcinoma (ESCC) tissues. Both the protein and messenger RNA expression levels of Paralemmin‐2 (PALM2) and Mitotic Arrest Deficient 2‐Like Protein (MAD2L1), regulated by miR‐200c‐5p, were notably higher in ESCC, and increased protein levels of PALM2 and MAD2L1 were correlated with adverse OS. PALM2 overexpression significantly enhanced ESCC cell migration. In conclusion, our study highlights the prognostic value of miR‐200 family in digestive system tumors, and the decrease of miR‐200c‐5p may promote ESCC invasion through upregulation of PALM2 and MAD2L1.
Examination tolerance, pre‐examination anxiety, knowledge needs and cooperation in gastroscopic examinees: A prospective, correlational analysis in a health screening population
Authors: Yang Yingzi , Xia Qing , Wu Liangyu , Luo Ruihua , Huang Haiyan , LYU Qiong , Wang Fei 
Published: August 2024

AbstractAimTo explore the correlations between examination tolerance and anxiety, knowledge needs and examination cooperation in sedation‐free gastroscopy examinees.DesignCross‐sectional survey using convenience sampling.MethodsA total of 170 healthy adults who underwent sedation‐free gastroenteroscopy were asked to complete a visual analogue scale (VAS) to rate their examination tolerance, the state anxiety questionnaire (S‐AI), a newly designed knowledge needs questionnaire and a cooperation questionnaire.ResultsThe VAS score was 4.47 ± 1.96, the state anxiety score was 39.46 ± 9.81, the total score for knowledge needs was 44.89 ± 11.02, and the average cooperation score was 2.47 ± 0.38. The VAS score during the examination positively correlated with the pretest state anxiety score and pretest knowledge needs score and negatively correlated with the examination cooperation score. The results of multiple linear regression analysis showed that after undergoing the examination for the first time, anxiety, body position and swallowing control were the main factors influencing the examination tolerance of sedation‐free gastroscopy examinees.Patient or Public ContributionWe would like to thank the staff and patients of the participating hospital for their assistance and cooperation in performing the current study.
An exploration of how construal level framing determines bequest giving behavior
Authors: Shang Jen , Routley Claire , Sargeant Adrian 
Published: August 2024

AbstractThis research tests the Construal‐Level Theory of Psychological Distance in a three‐dimensional context via a bequest fundraising telephone campaign. We experimentally primed temporal distance (i.e., 10 vs. 50 years) and social distance (i.e., donors' family and friends vs. benefits for wider society) before people answered a bequest‐related question. We then observed how matching and mismatching between these two dimensions impacted decisions differently depending on whether people engaged in a lower‐level thinking task (i.e., recalling whether they have left a bequest to a charity) or a higher‐level thinking task (i.e., considering whether they might leave a bequest in the future). Our findings contribute to the existing Construal‐Level Theory and nonprofit research by testing the unique combination of a three‐dimensional construal situation. Learning from this research can be applied to the design of innovative bequest fundraising procedures as well as innovative procedures to promote other voluntary decisions in the future.
Enhanced shape memory performance and numerical simulation of knitted‐fabric reinforced polymer composites with weft yarns
Authors: Huang Ying , Zhao Wei , Ren Haipeng , Jiang Liquan , Ouyang Yiwei , Xu Weilin , Liu Yang 
Published: August 2024

AbstractFabric‐reinforced shape memory polymeric composites (SMPC) have shown great potential in the design of intelligent deformation structures. In this work, the weft‐knitted fabric inserted with weft yarns was developed as reinforcement to fabricate the shape memory epoxy polymer (SMEP) composites. The effects of weft yarn, loop density and direction on the shape memory performance of SMPC under different bending radii were experimentally investigated. The results show that the SMPC have good shape fixity ratios and shape recovery ratios of around 98%. As compared with those of SMPCs without inserting weft yarns, the SMPCs with weft yarns have shorter shape recovery time, and the recovery force of SMPCs with weft yarns in the 0° and 90° directions shows an increase of 86.4% and 79.5%, respectively. The recovery force of SMPC improve 3.7 times compared to SMEP. The multiscale models of SMPC were established with basis of the results of micro‐computed tomography scanning of specimens and viscoelastic theory. The surface buckling behaviors of SMEP and SMPC specimens after U‐bending load were discussed. Finally, the deformation of loops and weft yarns of SMPC were analyzed to reveal the shape memory mechanism.Highlights
Shape memory polymeric composites (SMPC) with weft yarns has shorter shape recovery time.
Recovery force of SMPC with weft yarns was obvious enhanced.
Multi‐scale viscoelastic models of SMPC were established.
Surface buckling behaviors of SMPC after U‐bending load were revealed.
Multiple health outcomes associated with algae and its extracts supplementation: An umbrella review of systematic reviews and meta‐analyses
Authors: Wang Caixia , Min Ruixue , Zhou Qilun , Qi Yue , Ma Yanli , Zhang Xiaofeng 
Published: August 2024

AbstractAlgae and its extracts, widely consumed as functional foods, offer numerous health benefits; however, a comprehensive systematic summary of clinical evidence is currently lacking. The study was to assess the available evidence and provide an accurate estimate of the overall effects of algae and its extracts supplementation on various health outcomes. The comprehensive searches in PubMed, Scopus, Embase, Web of Science, and the Cochrane Library until December 22, 2023 were implemented. The random‐effects model was employed to pool the overall effect sizes (ESs) and the corresponding 95% confidence intervals (CIs) using Stata software. Moreover, detecting the methodological quality and evidence level of the eligible studies were employed by A Measurement Tool to Assess Systematic Review 2 (AMSTAR2) and the Grading of Recommendations Assessment Development and Evaluation. Ultimately, 25 articles covering 133 health outcomes were included in this umbrella review. The pooled results demonstrated that the algae and its extracts could significantly decrease body weight (ES = −1.65; 95% CI: −1.97, −1.34; p < 0.001), body mass index (BMI) (ES = −0.42; 95% CI: −0.78, −0.07; p = 0.020), waist circumference (WC) (ES = −1.40; 95% CI: −1.40, −1.39; p < 0.001), triglyceride (TG) (ES = −1.38; 95% CI: −2.15, −0.62; p < 0.001), total cholesterol (TC) (ES: −1.40; 95% CI: −2.09, −0.72; p < 0.001), very low‐density lipoprotein cholesterol (VLDL‐C) (ES = −7.85; 95% CI: −8.55, −7.15; p < 0.001), fasting blood glucose (ES = −2.68; 95% CI: −4.57, −0.79; p = 0.005), glycated hemoglobin (HbA1c) (ES = −0.15; 95% CI: −0.24, −0.07; p < 0.001), systolic blood pressure (ES = −3.21; 95% CI: −5.25, −1.17; p = 0.002), diastolic blood pressure (ES = −3.84; 95% CI: −7.02, −0.65; p = 0.018), alanine transaminase (ES = −0.42; 95% CI: −0.70, −0.14; p = 0.003), and alkaline phosphatase (ES = −0.54; 95% CI: −0.99, −0.10; p = 0.017). Due to the limited number of studies, no benefit was displayed on markers of inflammation and oxidative stress. Considering the suboptimal quality of studies and the insufficient articles pertaining to certain outcomes, further well‐designed research is imperative to substantiate the observed findings.
Dissection of potential anti‐osteoporosis mechanism of isopsoralen – a quality control marker in Psoraleae Fructus – by metabolite profiling and network pharmacology
Authors: Ruan Yan‐Jie , Wang Guo‐Wei , Chen Zi‐Hao , Tu Xin‐Pu , Han Chuan‐Bao , Shi Wei , Liu Jian‐Hang , Zhang Feng‐Xiang 
Published: August 2024

RationaleIsopsoralen (ISO), a quality control marker (Q‐marker) in Psoraleae Fructus, is proven to present an obvious anti‐osteoporosis effect. Until now, the metabolism and anti‐osteoporosis mechanisms of ISO have not been fully elucidated, greatly restricting its drug development.MethodsThe metabolites of ISO in rats were profiled by using ultrahigh‐performance liquid chromatography coupled with time‐of‐flight mass spectrometry. The potential anti‐osteoporosis mechanism of ISO in vivo was predicted by using network pharmacology.ResultsA total of 15 metabolites were characterized in rats after ingestion of ISO (20 mg/kg/day, by gavage), including 2 in plasma, 12 in urine, 6 in feces, 1 in heart, 3 in liver, 1 in spleen, 1 in lung, 3 in kidney, and 2 in brain. The pharmacology network results showed that ISO and its metabolites could regulate AKT1, SRC, NFKB1, EGFR, MAPK3, etc., involved in the prolactin signaling pathway, ErbB signaling pathway, thyroid hormone pathway, and PI3K‐Akt signaling pathway.ConclusionsThis is the first time for revealing the in vivo metabolism features and potential anti‐osteoporosis mechanism of ISO by metabolite profiling and network pharmacology, providing data for further verification of pharmacological mechanism.
High‐Performance Low‐Iridium Catalyst for Water Oxidation: Breaking Long‐Ranged Order of IrO2 by Neodymium Doping
Authors: Wang Yifan , Qin YuFeng , Wen Rou , Wang Longxiang , Dou Meiling , Wang Feng 
Published: August 2024

AbstractExploring efficacious low‐Ir electrocatalysts for oxygen evolution reaction (OER) is crucial for large‐scale application of proton exchange membrane water electrolysis (PEMWE). Herein, an efficient non‐precious lanthanide‐metal‐doped IrO2 electrocatalyst is presented for OER catalysis by doping large‐ionic‐radius Nd into IrO2 crystal. The doped Nd breaks the long‐ranged order structure by triggering the strain effect and thus inducing an atomic rearrangement of Nd─IrO2 involving the forming of Nd─O─Ir bonds along with an increased amount of oxygen vacancies (Ov), giving rise of a long‐ranged disorder but a short‐ranged order structure. The formed Nd─O─Ir bonds tailor the electronic structure of Ir, leading to a lowered d‐band center that weakens intermediates absorption on Ir sites. Moreover, doping Nd triggers Nd─IrO2 to catalyze OER mainly through lattice oxygen mechanism (LOM) by activating lattice oxygen owing to abundant Ov. The optimal catalyst only requires a relatively low overpotential of 263 mV@10 mA cm−2 with a high mass activity of 216.98 A gIr−1 (at 1.53 V) (eightfold of commercial IrO2), and also shows a superior durability at 50 mA cm−2 (20 h) than commercial IrO2 (3 h) due to the oxidation‐suppressing effect induced by Nd doping. This work offers insights into designing high‐performance low‐Ir electrocatalysts for PEMWE application.
Antibody‐Directing Antibody Conjugates (ADACs) Enabled by Orthogonal Click Chemistry for Targeted Intracellular Delivery
Authors: Gong Shuai , Liu Bin , Qiu Jingyi , Huang Fangying , Thayumanavan S. 
Published: August 2024

AbstractUsing orthogonal click chemistries for efficient nanoscale self‐assembly, a new antibody‐directing antibody conjugate (ADAC) nanogel is generated. In this system, one of the antibodies is displayed on the nanogel surface to specifically recognize cell‐surface epitopes while the other antibody is encapsulated inside the nanogel core. The system is programmed to release the latter antibody in its functional form in the cytosolic environment of a specific cell to engage intracellular targets. ADACs offer a potential solution to harness the advantages seen with antibody‐drug conjugates (ADCs) to deliver therapeutic cargos to specific tissues, but with the added capability of carrying biologics as the cargo. In this manuscript, this potential is demonstrated through delivery of antibodies against intracellular targets in specific cells. This platform offers new avenues for precise therapeutic interventions and the potential to address previously “undruggable” cellular targets.