bluuebunny/crossref_metadata_2025_split huggingface dataset:
An enzootic outbreak of acute disease associated with pathogenic E. coli in Adler monkey colony
Authors: Lapin Boris A. , Yakovleva Lelita A. , Dzhikidze Eteri K. , Gvozdik Tatiana E. , Agumava Aslan A. , Stasilevich Zinaida K. , Danilova Irina G. 
Published: July 2015

AbstractBackgroundIn spring 2009 in Adler colony of the Institute of Medical Primatology, a large enzootic outbreak of acute intestine infection associated with pathogenic E. coli occurred and caused 5% mortality of population (209 animals).MethodsThe epidemiological analysis, bacteriological investigation, postmortem examination, histological analysis, and PCR were used to identify the infectious agent.ResultsMarked hemorrhagic diathesis, lethargy, dehydration, diarrhea with blood, wasting, and sometimes dystrophic changes in articular cartilages were noted. Morphologically, hemorrhagic enterocolitis and massive hemorrhages were found. PCR investigation of bacteriologically isolated E. coli characterized it as enteropathogenic and enteroinvasive E. coli.ConclusionsThe outbreak in Adler colony slightly differed from similar outbreak in Florida in 2014 by more marked hemorrhagic diathesis and articular changes in some monkeys caused by polyavitaminosis developed in the course of infection. Sensitive to infection were M. mulatta, M. fascicularis, Cercopithecus aethiops, P. hamadryas and anubis, and Cebus capucinus.
Making Visible a Theory‐Guided Advance Care Planning Intervention
Authors: Song Mi‐Kyung , Ward Sandra E. 
Published: July 2015

AbstractPurposeIn reports of end‐of‐life communication interventions, it is difficult to find sufficient detail about the intervention to allow replication, extension, and translation into practice. The purpose of this article is to provide details about a theory‐guided advance care planning intervention, sharing the patient's illness representations to increase trust (SPIRIT), an intervention that has been shown to be efficacious for patients and their surrogates with respect to preparation for end‐of‐life decision making.Methods and DesignThe description of SPIRIT is based on an intervention description checklist by Conn (2012), the Intervention Taxonomy from Schulz, Czaja, McKay, Ory, and Belle (2010) and on relevant segments of Consolidated Standards of Reporting Trials.DiscussionThe SPIRIT intervention was developed based on sound theoretical underpinnings and pilot tested with target patient populations and racial or ethnic groups. We describe details about the intervention's theoretical basis, requisite intervener training, implementation of each intervention component, and fidelity monitoring.Clinical RelevanceThe details about the components of a theory‐guided advance care planning intervention may facilitate translation of the intervention to practice settings.
Torn between dual roles: the experiences of nurse‐family members when a loved one is hospitalised in a critical condition
Authors: Giles Tracey M , Williamson Victoria 
Published: July 2015

Aims and objectivesTo understand and interpret the experiences of nurse‐family members when a family member or loved one is hospitalised in a critical condition.BackgroundHaving a family member hospitalised with a critical illness is a traumatic stressor, often with long‐term sequelae. Providing holistic care for family members who are also nurses makes the provision of care more complex because of their professional expertise; yet few studies have explored this issue.DesignIn this descriptive study, qualitative data were collected using a questionnaire and analysed using van Manen's (Researching Lived Experience: Human Science for an Action Sensitive Pedagogy, 1990, State University of New York Press, London, ON) six‐step approach.MethodsTwenty nurse‐family members completed an online questionnaire in June 2013. Qualitative findings from 19 participants were included in the analysis. The phenomenological analysis approach described by van Manen (Researching Lived Experience: Human Science for an Action Sensitive Pedagogy, 1990, State University of New York Press, London, ON) was used to describe and interpret nurse‐family member experiences.ResultsNurse‐family members experience significant dual role conflicts between their personal and professional personas due to their specialised knowledge, need for watchfulness and competing expectations. Our findings describe how dual role conflicts developed and were managed, and reveal the resultant emotional toll and psychological distress as nurse‐family members struggled to resolve these conflicts.ConclusionsNurse‐family members require a different type of care than general public family members, yet their unique needs are often unmet, leading to increased anxiety and distress that could potentially be minimised. An increased awareness and emphasis on the nurse‐family member experience can ensure health care professionals are better placed to provide appropriate and targeted care to minimise distressing dual role conflicts.Relevance to clinical practiceThere is a need for targeted and specialised communication appropriate to each nurse‐family members' needs and level of understanding, and to clarify expectations to ensure nurse‐family members' professional knowledge and skills are recognised and respected without being exploited.
Relationship between dialysis adequacy and sleep quality in haemodialysis patients
Authors: Tosun Nuran , Kalender Nurten , Cinar Fatma Ilknur , Bagcivan Gulcan , Yenicesu Mujdat , Dikici Dilek , Kaya Dilek 
Published: July 2015

Aim and objectivesThe aim of this study is to examine the relationship between dialysis adequacy and sleep quality in haemodialysis patients.BackgroundSleep problems are common in haemodialysis patients. Dialysis adequacy is one of the factors associated with sleep quality. Studies evaluating the association between dialysis adequacy and sleep quality in haemodialysis patients present different results.DesignDescriptive and cross‐sectional study.MethodsThis study was performed with a total of 119 patients who had applied to dialysis centres for haemodialysis treatment between January and March 2014. The data collection form consists of socio‐demographic and medical characteristics as well as laboratory parameters. A modified Post‐Sleep Inventory was used to examine sleep quality in the research.ResultsThere were no statistically significant relationship between sleep quality and dialysis adequacy (p > 0·05). When the Post‐Sleep Inventory scores were evaluated according to sleep quality, 63·0% of patients had poor sleep quality, and 37·0% had good sleep quality. Sleep quality was worse in unemployed patients (X2 = 4·852; p = 0·025) and patients who smoked heavily (Z = 2·289; p = 0·022).ConclusionsIn this study, there is no statistically significant relationship between dialysis adequacy and sleep quality. However, it was found that the majority of haemodialysis patients had poor sleep quality.Relevance to clinical practiceEven if the dialysis adequacy of patients is at the recommended level, their sleep qualities may be poor. Therefore, evaluations of the sleep quality of haemodialysis patients during the clinical practice must be taken into consideration.
The perspective of children on factors influencing their participation in perioperative care
Authors: Sjöberg Carina , Amhliden Helene , Nygren Jens M , Arvidsson Susann , Svedberg Petra 
Published: July 2015

Aims and objectivesTo describe the experiences of participation in perioperative care of 8‐ to 11‐year‐old children.BackgroundAll children have the right to participate in decisions that affect them and have the right to express their views in all matters that concern them. Allowing children to be involved in their perioperative care can make a major difference in terms of their well‐being by decreasing fear and anxiety and having more positive experiences. Taking the views of children into account and facilitating their participation could thus increase the quality of care.DesignDescriptive qualitative design.MethodsThe study was conducted in 2013 and data were collected by narrative interviews with 10 children with experience from perioperative care in Sweden. Qualitative content analysis was chosen to describe the variations, differences and similarities in children's experiences of participation in perioperative care.ResultsThe result showed that receiving preparatory information, lack of information regarding postoperative care and wanting to have detailed information are important factors for influencing children's participation. Interaction with healthcare professionals, in terms of being listened to, being a part of the decision‐making and feeling trust, is important for children's participation in the decision‐making process. Poor adaptation of the care environment to the children's needs, feeling uncomfortable while waiting and needs for distraction are examples of how the environment and the care in the operating theatre influence the children's experiences of participation.ConclusionsEfforts should be made to improve children's opportunities for participation in the context of perioperative care and further research is needed to establish international standards for information strategies and care environment that promotes children's participation in perioperative care.Relevance to clinical practiceNurse anaesthetists need to acquire knowledge and develop strategies for providing preparatory visits and information to children prior to surgery as well as reducing waiting times and creating environments with meaningful and tailored opportunities for distraction in perioperative care.
mHealth SMS text messaging interventions and to promote medication adherence: an integrative review
Authors: DeKoekkoek Tracy , Given Barbara , Given Charles W , Ridenour Kimberly , Schueller Monica , Spoelstra Sandra L 
Published: July 2015

Aims and objectivesThis article is an integrative review of the evidence for mobile health Short Message Service text messages as an innovative and emerging intervention to promote medication adherence. Authors completed this review to draw conclusions and implications towards establishing a scientific foundation for use of text messages to promote medication adherence, thus informing clinical practice.BackgroundThe World Health Organization has identified medication adherence as a priority global problem. Text messages are emerging as an effective means of improving health behaviours and in some diseases to promote medication adherence. However, a gap in the literature indicates lack of evidence in guiding theories and content of text messages, which should be synthesised prior to use in clinical practice.DesignIntegrative review.MethodsCumulative Index to Nursing and Allied Health Literature, Excerpta Medica dataBASE, Scopus, the Cochrane Library and PubMed were searched for relevant studies between 2004–2014. Inclusion criteria were (1) implementation of a text‐message intervention and (2) medication adherence to a prescribed oral medication as a primary outcome. Articles were assessed for quality of methodology and measures of adherence. An integrative review process was used to perform analysis.ResultsThirteen articles meeting the inclusion criteria are included in this review. Nine of 13 studies found adherence rates improved between 15·3—17·8% when using text messages to promote medication adherence. Text messages that were standardised, tailored, one‐ or two‐way and timed either daily to medication regimen, weekly or monthly showed improvement in medication adherence.ConclusionsThis review established a scientific basis for text messages as an intervention to improve medication adherence across multiple diseases. Future large rigorous randomised trials are needed to further test text messaging interventions.Relevance to clinical practiceThis review provides clinicians with the state of the science with regard to text messaging interventions that promote medication adherence. A description of intervention components are provided to aid nurses in development of text messages and in translating evidence into practice.
Schenker, Cube and Schubert's ‘Der Doppelgänger’
Authors: BRETHERTON DAVID 
Published: July 2015

ABSTRACTSchubert's ‘Der Doppelgänger’ is among the composer's most‐analysed works. Yet, in spite of numerous published Schenkerian readings, Schenker's own analytical sketches of the song remain largely neglected. His work on ‘Der Doppelgänger’ was prompted by a letter from Felix‐Eberhard von Cube of 8 May 1932, which enclosed a voice‐leading analysis. Although this analysis does not survive, the broad outline of Cube's reading can be reconstructed from the letter. Schenker's reply to Cube is not known to survive, but a diary entry of 17 July 1932 records work on the song and the sending of a ‘solution’ to his former pupil; sketches in the Oster Collection, also dating from 17 July 1932, further document the theorist's work on the song that day.Schenker appears to settle on an Urlinie that descends from , in contrast to the primary tone of that features not only in Cube's original analysis but also in many recently published ones. In choosing a ‐line, Schenker places great weight on the relationship between the song's Urlinie and its four‐note ostinato motive, and the sketches illustrate how his concerns are similar to those of modern‐day theorists working three‐quarters of a century later.
Identification of a naturally processed HLA‐Cw7‐binding peptide that cross‐reacts with HLA‐A24‐restricted ovarian cancer‐specific CTLs
Authors: Yamada E. , Demachi‐Okamura A. , Kondo S. , Akatsuka Y. , Suzuki S. , Shibata K. , Kikkawa F. , Kuzushima K. 
Published: July 2015

AbstractHere, we describe an human leukocyte antigen (HLA)‐A*24:02‐restricted cytotoxic T‐lymphocyte (CTL) clone, 1G3, established from naïve CD8+ T‐lymphocytes obtained from a healthy donor stimulated with HLA‐modified TOV21G, an ovarian cancer cell line. The 1G3 clone responds not only to ovarian cancer cells in the context of HLA‐A*24:02 but also to allogeneic HLA‐Cw*07:02 molecules through cross‐reactive T‐cell receptor recognition. Expression screening using a complementary DNA library constructed from TOV21G messenger RNA revealed that this alloreactivity was mediated through the nine‐mer peptide VRTPYTMSY, derived from RNA‐binding motif protein 4. To our knowledge, this study presents the first example of the allorecognition of an HLA‐Cw molecule by HLA‐A‐restricted T‐cells, thereby revealing a naturally processed epitope peptide. These findings provide the structural bases for the allorecognition of human T‐cells. In addition, this study suggests that unexpected alloresponses occur in certain HLA combinations, and further study is needed to understand the mechanisms of alloreactivity for better prediction of alloresponses in clinical settings.
JC polyomavirus nephropathy confirmed by using an in‐house polymerase chain reaction method
Authors: Querido S. , Jorge C. , Sousa H. , Birne R. , Matias P. , Weigert A. , Adragão T. , Bruges M. , Ramos S. , Santos M. , Paixão P. , Curran M.D. , Machado D. 
Published: July 2015

AbstractWe report the case of an isolated JC virus (JCV) infection, without co‐infection by polyoma BK virus (BKV), associated with nephropathy 4 years after kidney transplantation. Clinical suspicion followed the observation of a decrease in estimated glomerular filtration rate (eGFR) and a renal allograft biopsy revealing polyomavirus‐associated tubulointerstitial nephritis and positivity for SV40. An in‐house real‐time polymerase chain reaction assay, targeting the presence of JCV and the absence of BKV in biopsy tissue, confirmed diagnosis. Thirteen months after diagnosis, and following therapeutic measures, eGFR remains stable.
Phototropins maintain robust circadian oscillation of PSII operating efficiency under blue light
Authors: Litthauer Suzanne , Battle Martin W. , Lawson Tracy , Jones Matthew A. 
Published: July 2015

SummaryThe circadian system allows plants to coordinate metabolic and physiological functions with predictable environmental variables such as dusk and dawn. This endogenous oscillator is comprised of biochemical and transcriptional rhythms that are synchronized with a plant's surroundings via environmental signals, including light and temperature. We have used chlorophyll fluorescence techniques to describe circadian rhythms of PSII operating efficiency () in the chloroplasts of Arabidopsis thaliana. These oscillations appear to be influenced by transcriptional feedback loops previously described in the nucleus, and are induced by rhythmic changes in photochemical quenching over circadian time. Our work reveals that a family of blue photoreceptors, phototropins, maintain robust rhythms of under constant blue light. As phototropins do not influence circadian gene expression in the nucleus our imaging methodology highlights differences between the modulation of circadian outputs in distinct subcellular compartments.
Estradiol‐induced alopecia in five dogs after contact with a transdermal gel used for the treatment of postmenopausal symptoms in women
Authors: Wiener Dominique J. , Rüfenacht Silvia , Koch Hans J. , Mauldin Elizabeth A. , Mayer Ursula , Welle Monika M. 
Published: July 2015

BackgroundNoninflammatory alopecia is a frequent problem in dogs. Estrogen‐induced alopecia is well described in dogs, with estrogen producing testicular tumors and canine female hyperestrogenism.ObjectivesTo increase awareness that extensive alopecia in dogs can be caused by exposure to estradiol gel used by owners to treat their postmenopausal symptoms.AnimalsSkin biopsies from five dogs with extensive alopecia were examined.MethodsOwners were asked for a thorough case history, including possible exposure to an estradiol gel. Complete blood work and serum chemistry panel analysis were performed to investigate possible underlying causes. Formalin‐fixed skin biopsy samples were obtained from lesional skin and histopathology was performed.ResultsAll owners confirmed the use of a transdermal estradiol gel and close contact with the affected dogs before development of alopecia. Histopathologic examination showed a similar picture in all five dogs. Most hair follicles were predominantly either in kenogen or telogen and hair follicle infundibula showed mild to moderate dilation. Hair regrowth was present in all five dogs after the exposure to the estradiol gel was stopped or minimized. Blood work and serum chemistry panel were within normal limits in all cases. One dog had elevated estradiol concentrations, whereas in another dog estradiol concentrations were within normal limits.Conclusion and clinical importanceAlopecia can occur after contact with a transdermal gel used as treatment for postmenopausal symptoms in women. Estradiol gel used by female owners therefore represents a possible cause for noninflammatory alopecia in dogs. Estradiol concentrations are not necessarily elevated in affected dogs.
Effects of Yoga on Stress, Stress Adaption, and Heart Rate Variability Among Mental Health Professionals—A Randomized Controlled Trial
Authors: Lin Shu‐Ling , Huang Ching‐Ya , Shiu Shau‐Ping , Yeh Shu‐Hui 
Published: July 2015

ABSTRACTBackgroundMental health professionals experiencing work‐related stress may experience burn out, leading to a negative impact on their organization and patients.AimThe aim of this study was to examine the effects of yoga classes on work‐related stress, stress adaptation, and autonomic nerve activity among mental health professionals.MethodsA randomized controlled trial was used, which compared the outcomes between the experimental (e.g., yoga program) and the control groups (e.g., no yoga exercise) for 12 weeks. Work‐related stress and stress adaptation were assessed before and after the program. Heart rate variability (HRV) was measured at baseline, midpoint through the weekly yoga classes (6 weeks), and postintervention (after 12 weeks of yoga classes).ResultsThe results showed that the mental health professionals in the yoga group experienced a significant reduction in work‐related stress (t = −6.225, p < .001), and a significant enhancement of stress adaptation (t = 2.128, p = .042). Participants in the control group revealed no significant changes. Comparing the mean differences in pre‐ and posttest scores between yoga and control groups, we found the yoga group significantly decreased work‐related stress (t = −3.216, p = .002), but there was no significant change in stress adaptation (p = .084). While controlling for the pretest scores of work‐related stress, participants in yoga, but not the control group, revealed a significant increase in autonomic nerve activity at midpoint (6 weeks) test (t = −2.799, p = .007), and at posttest (12 weeks; t = −2.099, p = .040).Linking Evidence to ActionBecause mental health professionals experienced a reduction in work‐related stress and an increase in autonomic nerve activity in a weekly yoga program for 12 weeks, clinicians, administrators, and educators should offer yoga classes as a strategy to help health professionals reduce their work‐related stress and balance autonomic nerve activities.
The Effect of Foot Reflexology on Acute Pain in Infants: A Randomized Controlled Trial
Authors: Koç Tuba , Gözen Duygu 
Published: July 2015

ABSTRACTAimThis study was a randomized controlled trial designed to evaluate the effect of foot reflexology applied on infants on acute pain that may arise after vaccine injection.MethodsThe sample consisted of 1‐ to 12‐month‐old infants registered in a family health center in Istanbul, Turkey, for healthcare follow‐up. A total of 60 infants who met the criteria of the sample group were included in the study; 30 infants constituted the reflexology group and the other 30 constituted the control group. Although questionnaire forms were used to determine the descriptive characteristics of infant‐mother pairs, the Face, Legs, Activity, Cry, Consolability (FLACC) Pain Assessment Scale was used to evaluate pain level. Infants in the reflexology group received reflexology treatment for an average of 20–30 minutes before vaccination, depending on the physical size of the infant's foot. Pain, heart rate, oxygen saturation levels, and crying periods of infants in the reflexology and control groups were evaluated before and after vaccination.ResultsThe FLACC pain score was observed to be statistically similar between groups. After reflexology was applied to infants in the reflexology group before vaccination, it was determined that the pain score was reduced to .50 ± 1.14. In the examination performed after vaccination, FLACC pain score was found to be 5.47 ± 2.11 in the reflexology group and 9.63 ± .85 in the control group. A statistically significant difference was observed between the mean FLACC pain scores of infants in the reflexology and control groups (p = .000). The infants in the reflexology group also had lower heart rates, higher oxygen saturation, and shorter crying periods than the infants in the control group (p <.001).Linking Evidence to ActionsReflexology before vaccine reduced the pain level experienced after vaccination. Future research needs to explore different interventional practices.