bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical outcomes and risk factors in patients with COVID‐19 and autoimmune rheumatic diseases: insights from a major Australian hospital study
Authors: Ling Zhi , Guy Stephen , Fong Christopher 
Published: August 2024

AbstractBackground and AimPatients with autoimmune inflammatory rheumatic disease (AIIRD) are at higher risk of severe infections because of their underlying diseases and immunosuppression. Our objective was to elucidate the epidemiological and clinical characteristics of patients with AIIRD presenting with COVID‐19 and their relation to disease severity. We explored whether variables, including underlying diagnosis, disease‐modifying antirheumatic drugs (DMARDs) and COVID‐19 vaccine status, were associated with more severe forms of COVID‐19 infection.MethodsBetween 1 January 2020 and 30 June 2022, 151 patients with AIIRD and COVID‐19 infection were analysed using a binary regression model and a multinomial regression model.ResultsThe average age was 61.5 years, and average Charlson Comorbidity Index (CCI) was 2.1; 106 (70.2%) patients were diagnosed with rheumatoid arthritis (RA), and 70 (46.4%) patients were receiving prednisolone. In the multivariable logistic regression model, ages between 50 and 69 years (odds ratio (OR) = 5.85; 95% confidence interval (CI) = 1.35–25.25) and older than 70 years (OR = 5.29; 95% CI = 1.21–23.14), prior prednisolone treatment (OR = 7.09; 95% CI = 2.63–19.11) and vaccination status including one and two doses (OR = 0.19; 95% CI = 0.05–0.69) and three and four doses (OR = 0.09; 95% CI = 0.02–0.35) were all statistically significant factors related to changes in the severity level of COVID‐19.ConclusionSeverity of COVID‐19 infection in patients with AIIRD is affected by age, background steroid use and vaccination status. Factors including sex, comorbidity, diagnosis of AIIRDs and use of DMARDs, including conventional synthetic, biologics and targeted DMARDs, were not significantly associated with COVID‐19 severity.
Procreative Obligations and the Directed Duty of Care
Authors: Brandt Reuven 
Published: August 2024

ABSTRACTThere is much dispute about what we owe the children we are responsible for creating. Some argue that so long as we provide offspring with lives worth living we do no wrong. Others argue that our procreative obligations are weightier and oblige us to provide (or attempt to provide) our offspring with a reasonable opportunity to thrive, or meet some other standard beyond merely providing a life worth living. Our practices and intuitions on this matter are inconsistent. For example, gamete donors who intentionally participate in the project of creating a child are thought to have few obligations to their offspring, but those who create a child accidentally are thought to have weighty obligations. Furthermore, a justification for why we are obliged to provide offspring with more than a life worth living has been elusive. To resolve this puzzle I argue that an under‐theorized element of morality, the directed duty of care, explains why we owe our offspring more than a life worth living.
Ocean warming and novel species interactions boost growth and persistence of range‐extending tropical fishes but challenge that of sympatric temperate species in temperate waters
Authors: Sasaki Minami , Monaco Cristián J. , Booth David J. , Nagelkerken Ivan 
Published: August 2024

AbstractAimClimate change can have a broad range of impacts on the physiology and behaviour of animals. These effects can be mediated by the presence of other species in the community, but current forecasts of species responses to climate change largely ignore biological interactions. This is particularly true for novel interactions between range‐extending and native species, as this is often considered as noise and excluded from predictive models. Here we simulate how a tropical range‐extending and a local temperate fish species respond to the independent and combined effects of future ocean warming (RCPs 4.5 and 8.5) and novel ecological interactions in temperate ecosystems.LocationEast coast of Australia, along a ~ 2,000 km latitudinal gradient in a global climate warming hotspot.TaxonAbudefduf vaigiensis (tropical) and Atypicthys strigatus (temperate) fishes.MethodsWe use a dynamic energy budget model to simulate the length growth (i.e., increases in body length of individuals over time) and population persistence of juveniles of a tropical and a temperate fish species that form mixed‐species shoals, under different climate scenarios with and without the effects of novel ecological interactions.ResultsOur model forecasts that length growth of the juvenile tropical species will increase under ocean warming across subtropical to temperate regions. This increased length growth will be more drastic in temperate regions than in the subtropics, as winter warming will allow the tropical species to overwinter more frequently and show positive growth throughout the year. In contrast, warmer summer temperatures in the subtropics will likely exceed the optimal temperature of the juvenile temperate species at their trailing edge, resulting in reduced length growth under climate warming. Novel species interactions increased length growth of the juvenile tropical species but did not affect its winter or summer survival. In contrast, novel species interactions with tropical species were forecast to reduce length growth of the juvenile temperate species.Main ConclusionsOur study suggests that for some coastal fish species future warming will likely reverse body size dominance between temperate and tropical fish species, with increased novel interactions in temperate ecosystems (due to range extensions) but decreased novel interactions in the subtropics (due to range contractions). Novel species interactions and warming effects on body size and species survival are likely to reshuffle temperate fish communities and their competitive interactions.
Fitness consequences of population bottlenecks in an invasive blowfly
Authors: Croft Lilly , Matheson Paige , Butterworth Nathan J. , McGaughran Angela 
Published: August 2024

AbstractInvasive species often undergo demographic bottlenecks that cause a decrease in genetic diversity and associated reductions in population fitness. Despite this, they manage to thrive in novel environments. Investigating the effects of inbreeding and genetic bottlenecks on population fitness for invasive species is, therefore, key to understanding how they may survive in new environments. We used the blowfly Calliphora vicina (Sciences, Mathématiques et Physique, 1830, 2, 1), which is native to Europe and was introduced to Australia and New Zealand, to examine the effects of genetic diversity on population fitness. We first collected 59 samples from 15 populations across New Zealand and one in Australia, and used 20,501 biallelic SNPs to investigate population genomic diversity, structure and admixture. We then explored the impacts of repeated experimental bottlenecks on population fitness by creating inbred and outbred lines of C. vicina and measuring a variety of fitness traits. In wild‐caught samples, we found low overall genetic diversity, signals of genetic admixture and limited (<3%) genetic differentiation between North and South Island populations, with genetic links between the South Island and Australia. Following experimental bottlenecks, we found significant reductions in fitness for inbred lines. However, fitness effects were not felt equally across all phenotypic traits. Moreover, they were not enough to cause population collapse in any experimental line, suggesting that C. vicina (when under relaxed selection, as in laboratory settings) may be able to compensate for population bottlenecks even when highly inbred. Our results demonstrate the value of a tractable experimental system for investigating processes that may facilitate or hamper biological invasion.
Anti‐Ri‐antibodies associated paraneoplastic myelopathy revealing a woman's breast cancer: A case report
Authors: Zouari Rania , Ben Hmid Ahlem , Abdellatif Jihen , Zamali Imen , Saeid Mohamed Zakaria , Sassi Samia Ben , Ben Ahmed Melika 
Published: August 2024

AbstractParaneoplastic myelopathy (PM) is an enigmatic immune‐mediated disorder rarely associated with breast cancer (BC) and anti‐Ri antibodies. Sometimes diagnosis is difficult due to the heterogeneity of symptoms and the timing of their onset. Herein, we report the case of a woman presenting with cervical myelopathy causing spastic left hemiplegia and painful spasms. Diagnosis of PM was confirmed through the positivity of well‐characterized onconeural antibodies (anti‐Ri) and the discovery of BC after a clinical examination and multiple investigations. We highlight, through this case, the importance of onconeural antibodies in the diagnosis of paraneoplastic neurological syndromes and associated cancer.
Biomodulation effects induced by ultrasound stimulation in periodontal cells implicated in orthodontic tooth movement: A systematic review
Authors: Pascoal Selma , Monteiro Francisca , Oliveira Sofia , Simoni Arianna , Carvalho Óscar , Pinho Teresa 
Published: August 2024

AbstractAccelerating orthodontic tooth movement (OTM) is increasingly important for shorter treatment times, which reduces periodontal risks, root resorption and dental caries. Techniques to accelerate OTM focus on stimulating bone remodelling by enhancing osteoclast and osteoblast activity and include both surgical and non‐surgical methods. The therapeutic potential of ultrasounds is highly recognized among many medical areas and has shown promising results in modulating bone remodelling and inflammation phenomena. This systematic review aims to collect and analyse the current scientific in vitro and ex vivo evidence on ultrasound stimulation (US) bioeffects in cells implicated in tooth movement. This review was conducted according to PRISMA 2020 guidelines. A bibliographic search was carried out in the PubMed, Scopus and Web of Science databases. Sixteen articles were selected and included in this review. The revised studies suggest that US of 1.0 and 1.5 MHz, delivered at 30 mW/cm2, 10 to 30 min daily over three to 14 days seems to be effective in promoting osteoclastogenic activity, while US of 1.5 MHz, 30 to 90 mW/cm2, in 5‐ to 20‐min sessions delivered daily for 5 to 14 days exhibits the potential to stimulate osteogenic activity and differentiation. Previous research yielded varied evidence of the effectiveness of US in orthodontics. Future animal studies should employ the recommended US parameters and investigate how distinct protocols can differentially impact tissue remodelling pathways. The knowledge arising from this review will ultimately potentiate the application of US to accelerate OTM in the clinical setting.
Food allergy in a changing dietary landscape: A focus on the Asia Pacific region
Authors: Leung Agnes Sze‐Yin , Pacharn Punchama , Tangvalelerd Supaluk , Sato Sakura , Pitt Erin , Wong Gary , Koplin Jennifer J. 
Published: August 2024

AbstractRecent studies have provided compelling evidence to suggest that various environmental factors play a significant role in the development of food allergies. As our society experiences rapid economic growth, increased urbanization, and a shift towards a more Westernized diet, the incidence of food allergies is also on the rise and the pattern is gradually evolving. This review will delve into the changes in the epidemiology of food allergies within the Asia‐Pacific region and the various dietary practices and factors that are postulated to play a role in the rise in food allergies over the years. Although there have been important advancements in the field of food allergies, there are still numerous uncertainties regarding the intricate relationship between diet and food allergies. Specifically, the role of epigenetic factors in influencing the susceptibility to food allergies, as evidenced by studies that assessed the impact of migration and rural–urban dynamics, is not fully understood. Addressing this knowledge gap presents an opportunity to develop more effective prevention and treatment strategies that could greatly benefit individuals living with food allergies.image
Relationship sustainability: Exploring the idea of sustainable marriages among Indian married couples
Authors: Barman Jeshmeen D. , Maheshwari Saurabh 
Published: August 2024

AbstractThe present study adopted the concept of sustainability to understand Indian marriages and proposed a new concept of relationship sustainability. Employing an exploratory sequential mixed‐method design, Study 1 involved 30 interviews with long‐term married couples (Mage = 44.70; Mmarriage years = 19.48) to understand their marital experiences. Thematic analysis identified three major factors that lead to sustainability in marital relationships: couple bonding (a close connection that binds two partners together), personal well‐being (partner's contributions toward one's well‐being), and partner's well‐being (one's contribution to the partner's well‐being). Findings from Study 1 were used to develop a relationship sustainability scale, which was then used in Study 2, a survey study. A survey was conducted on 415 long‐term married individuals (Male: 221, Female: 194; Mage = 43.55; Mmarriage years = 17.74) that included information about relationship commitment, satisfaction, and happiness, along with other variables. Data from 415 long‐term married individuals were collected. The results confirmed the applicability of the concept of relationship sustainability and also showed that relationship sustainability predicted marital outcomes, such as happiness and satisfaction. Overall, the results showed that to achieve marital well‐being, one needs to move toward a sustainable model of relationship where partners both together strive for long‐term relationship and personal goals.
The effects of spiritual wellbeing on life satisfaction in hematologic cancer patients aged 65 and older in Turkey: mediating role of hope
Authors: Bahcecioglu Turan Gülcan , Özer Zülfünaz , YanmıŞ Safiye 
Published: August 2024

AbstractBackgroundThe mediating role of hope in the effects of spiritual wellbeing on life satisfaction in elderly haematologic cancer patients in Turkey was investigated in the present study.MethodsThe study was conducted in a descriptive, cross‐sectional and correlational design. The study was conducted with 150 patients aged 65 and older who were diagnosed with haematologic cancer and who were referred to a university hospital haematology clinic and outpatient clinic. Research data were collected with Descriptive Information Form, Dispositional Hope Scale (DHS), Spiritual Well‐being Scale (FACIT‐Sp‐12) and Satisfaction with Life Scale (SWLS).ResultsFACIT‐Sp‐12 score was 37.25 ± 7.29; DHS score was 40.42 ± 8.29, SWLS score was 16.24 ± 8.79. FACIT‐Sp‐12 (β = 0.668) and DHS (β = 0.226) were found to affect SWLS positively. In terms of the effect of FACIT‐Sp‐12 on SWLS, DHS has a mediating role and makes the positive effect of FACIT‐Sp‐12 on SWLS stronger (β = 0.771).ConclusionsSpiritual wellbeing levels of the participants in our study were found to be high, while their levels of satisfaction with life and hope were found to be moderate. It was also concluded that spiritual wellbeing had a direct effect on satisfaction with life and an indirect effect through the mediating role of hope.
THYLAKOID FORMATION 1 interacts with FLOWERING LOCUS T and modulates temperature‐responsive flowering in Arabidopsis
Authors: Susila Hendry , Gawarecka Katarzyna , Youn Geummin , Jurić Snježana , Jeong Hyewon , Ahn Ji Hoon 
Published: August 2024

SUMMARYThe intracellular localization of the florigen FLOWERING LOCUS T (FT) is important for its long‐distance transport toward the shoot apical meristem. However, the mechanisms regulating the FT localization remain poorly understood. Here, we discovered that in Arabidopsis thaliana, the chloroplast‐localized protein THYLAKOID FORMATION 1 (THF1) physically interacts with FT, sequestering FT in the outer chloroplast envelope. Loss of THF1 function led to temperature‐insensitive flowering, resulting in early flowering, especially under low ambient temperatures. THF1 mainly acts in the leaf vasculature and shoot apex to prevent flowering. Mutation of CONSTANS or FT completely suppressed the early flowering of thf1‐1 mutants. FT and THF1 interact via their anion binding pocket and coiled‐coil domain (CCD), respectively. Deletion of the CCD in THF1 by gene editing caused temperature‐insensitive early flowering similar to that observed in the thf1‐1 mutant. FT levels in the outer chloroplast envelope decreased in the thf1‐1 mutant, suggesting that THF1 is important for sequestering FT. Furthermore, THF1 protein levels decreased in seedlings grown at high ambient temperature, suggesting an explanation for its role in plant responses to ambient temperature. A thf1‐1 phosphatidylglycerolphosphate synthase 1 (pgp1) double mutant exhibited additive acceleration of flowering at 23 and 16°C, compared to the single mutants, indicating that THF1 and phosphatidylglycerol (PG) act as independent but synergistic regulators of temperature‐responsive flowering. Collectively, our results provide an understanding of the genetic pathway involving THF1 and its role in temperature‐responsive flowering and reveal a previously unappreciated additive interplay between THF1 and PG in temperature‐responsive flowering.
New faunistic data on Cunaxidae (Acari: Bdelloidea) of Asian Russia
Authors: Khaustov Alexander , Khaustov Vladimir 
Published: August 2024

New faunistic data on mites of the family Cunaxidae of Asian Russia are provided. A total of 11 species were found, among them four species are described as new for science, namely, Neobonzia scutata sp. nov., Cunaxa palustris sp. nov., C. quinquesetosa sp. nov., and Cunaxoides magnificus sp. nov. Scirula impressa Berlese is recorded from Russia for the first time and redescribed; Cunaxoides trepidus Kuznetsov and Livshitz recorded from Asian Russia for the first time and redescribed; Armascirus fendai Kalúz and Vrabec and Cunaxoides lootsi Den Heyer are recorded from Russia for the first time; Cunaxa gordeevae Sergeyenko, C. anomala Khaustov and Kuznetsov, and Cunaxoides desertus Kuznetsov and Livshitz are recorded from Asian Russia for the first time.
Characterization of differences in seed endophytic microbiome in conventional and organic rice by amplicon-based sequencing and culturing methods
Authors: Khanal Sabin , Imran Muhammad , Zhou Xin-Gen , Antony-Babu Sanjay 
Published: August 2024

ABSTRACT

The seed serves as the primary source for establishing microbial populations in plants across subsequent generations, influencing plant growth and overall health. Cropping conditions, especially farming practices, can influence the composition and functionality of the seed microbiome. Very little is known about the differences in seed microbiome between organic and conventional production systems. In this study, we characterized the endophytic microbial populations in seeds of rice grown under organic and conventional management practices through culture-dependent and -independent analyses. The V4 region of 16S rRNA was used for bacterial taxa identification, and the ITS1 region was used for the identification of fungal taxa. Our results revealed significantly higher Shannon and Simpson indices for bacterial diversity in the conventional farming system, whereas the fungal diversity was higher for observed, Shannon, and Simpson indices in the organic farming system. The cultivable endophytic bacteria were isolated and identified using the full-length 16S rRNA gene. There was no difference in culturable endophytic bacterial isolates in rice seeds grown under both conventional and organic farming systems. Among 33 unique isolates tested
in vitro
, three bacteria—
Bacillus
sp. ST24,
Burkholderia
sp. OR5, and
Pantoea
sp. ST25—showed antagonistic activities against
Marasmius graminum, Rhizoctonia solani
AG4, and
R. solani
AG11, the fungal pathogens causing seedling blight in rice.

IMPORTANCE
In this paper, we studied the differences in the endophytic microbial composition of rice seeds grown in conventional and organic farming systems. Our results demonstrate a greater bacterial diversity in conventional farming, while organic farming showcases a higher fungal diversity. Additionally, our research reveals the ability of seed bacterial endophytes to inhibit the growth of three fungal pathogens responsible for causing seedling blight in rice. This study provides valuable insights into the potential use of beneficial seed microbial endophytes for developing a novel microbiome-based strategy in the management of rice diseases. Such an approach has the potential to enhance overall plant health and improve crop productivity.
Odd annular Bar-Natan category and 𝔤𝔩(1|1)
Authors: Necheles Casey , Wehrli Stephan 
Published: August 2024

In this paper, we introduce two monoidal supercategories: the odd dotted Temperley–Lieb category [Formula: see text], which is a generalization of the odd Temperley–Lieb category studied by Brundan and Ellis in [Monoidal Supercategories, Commun. Math. Phys. 351 (2017) 1045–1089], and the odd annular Bar-Natan category [Formula: see text], which generalizes the odd Bar-Natan category studied by Putyra in [A [Formula: see text]-category of chronological cobordisms and odd Khovanov homology, Banach Center Publ. 103 (2014) 291–355]. We then show there is an equivalence of categories between them if [Formula: see text]. We use this equivalence to better understand the action of the Lie superalgebra [Formula: see text] on the odd Khovanov homology of a knot in a thickened annulus found by Grigsby and the second author in [An action of [Formula: see text] on odd annular Khovanov homology, Math. Res. Lett. 27(3) (2020) 711–742].