bluuebunny/crossref_metadata_2025_split huggingface dataset:
Factors affecting the diffusion of integrated reporting – a UK FTSE 100 perspective
Authors: Robertson Fiona Ann , Samy Martin 
Published: April 2015

Purpose– This study seeks to investigate the likely adoption of integrated reporting (IR), in addition to highlighting the limitations of current reporting practices. In particular, the analysis in this study used the characteristics of diffusion of innovation theory to investigate how perceptions of IR as offering a relative advantage over existing practices; its compatibility to existing organisational values, past experiences and needs; and its perceived complexity impacted on the adoption and diffusion of IR.Design/methodology/approach– Methodology was based on a content analysis of 22 UK FTSE 100 annual and sustainability reports across industries. To build a phenomenological triangulation research approach, semi-structured interviews were conducted with ten senior managers to ascertain their perceptions of current SR practices and IR.Findings– The analysis in this study revealed that low/medium levels of linkages exist between the majority of reports in the sample, thus limiting their usefulness. Based on these findings, this study suggests that senior managers perceive IR as having a relative advantage over existing practice. Overall, the senior managers interviewed were supportive of IR and this research revealed that many companies are starting to integrate their reporting along IR guidelines. This study further identifies factors that are likely to impact on more widespread diffusion of IR.Research limitations/implications– The sample size to assess linkages between reports was based on a sample of company reports across industries to give a balanced view of reporting practices. This could be viewed as a limitation as it was not a representative sample of the population as a whole. Another limitation of this research study was the small sample of organisations that participated in the interview process, and the single country focus.Practical implications– This study has identified several factors that were likely to impact on wider spread diffusion of IR, which should be of interest to practitioners in this field as well as those considering the adoption of IR.Originality/value– As an emerging phenomenon, there are few empirical studies exploring IR practices and perceptions. To the best of the authors' knowledge, this is the first paper that provides some insights into IR from a UK perspective.
Broadening out and opening up: an agonistic attitude toward progressive social accounting
Authors: Dillard Jesse , Brown Judy 
Published: April 2015

Purpose– The purpose of this paper is to review the current research program in agonistic dialogic accounting and to reflect on future possibilities for broadening out and opening up accounting and accountability systems, especially as they relate to social and environmental accounting (SEA).Design/methodology/approach– The authors describe an ethic of accountability as a context for dialogue and debate intended to broaden out and open up new imaginings of accounting for democracy. The authors review the accounting literature addressing dialogic accounting and agonistics as the precursor of what has evolved into agonistic dialogic accounting. The authors discuss their work to date on agonistic pluralism and engagement, recognizing the necessity of linking the normative framework to an effective political program. The authors review prior studies applying science and technology studies that have addressed these issues.Findings– The authors consider how the application of agonistic ideas might facilitate the development of multiple accountings that take pluralism seriously by addressing constituencies and perspectives often marginalized in both SEA and mainstream accounting. An ethic of accountability and science and technology studies are useful for stimulating dialogue and debate regarding democratic and civil society institutions as they relate to economic entities, especially corporations.Practical implications– Agonistic dialogic accounting in conjunction with other disciplines such as science and technology studies can be used in formulating, implementing and evaluating policy for advancing a progressive social agenda.Originality/value– A reflective view of the current work in agonistic dialogic accounting highlights considerations for further research regarding the possible interdisciplinary work particularly with science and technology studies in broadening out and opening up accounting and accountability systems as facilitators of progressive social agenda.
Successful adalimumab treatment of a psoriasis vulgaris patient with hemodialysis for renal failure: A case report and a review of the previous reports on biologic treatments for psoriasis patients with hemodialysis for renal failure
Authors: Kusakari Yoshiyuki , Yamasaki Kenshi , Takahashi Toshiya , Tsuchiyama Kenichiro , Shimada‐Omori Ryoko , Nasu‐Tamabuchi Mei , Aiba Setsuya 
Published: April 2015

AbstractThe efficacy and safety of biologic treatments have been established in patients with moderate to severe psoriasis, but there are few reports on biologic therapy for patients with psoriasis complicated by end‐stage renal failure on hemodialysis (HD). In this report, we demonstrated the efficacy and safety of adalimumab for patients with severe psoriasis on HD. A 46‐year‐old Japanese man with a 14‐year history of psoriasis was referred to our clinic in September 2009. He had developed hypertension and renal failure during a 7‐year history of cyclosporin treatment. With the infliximab treatment, he achieved 75% improvement of the Psoriasis Area and Severity Index (PASI) score within 3 months from the PASI of 42.3 before the treatment. However, his renal failure gradually deteriorated, and HD was initiated at 1 year after the introduction of infliximab. Because of hydration during the i.v. injection of infliximab, he developed pulmonary edema with every infliximab treatment after starting HD. We switched to ustekinumab treatment, but his psoriasis was not improved. Then, we switched to adalimumab and achieved a PASI‐100 response within 2 months. The patient received adalimumab treatment for more than a year without any adverse effects. In addition to our case, five articles reported cases of psoriasis patients with renal failure on HD who were treated with biologics. The psoriatic lesions were improved by biologics in these cases, and no severe adverse effects on the renal function were reported. Thus, biologics are a reasonable treatment option for patients with severe psoriasis with renal failure on HD.
Betapapillomavirus in multiple non‐melanoma skin cancers of Netherton syndrome: Case report and published work review
Authors: Guerra Liliana , Fortugno Paola , Sinistro Anna , Proto Vittoria , Zambruno Giovanna , Didona Biagio , Castiglia Daniele 
Published: April 2015

AbstractNetherton syndrome (NS) is a rare genetic disease presenting with ichthyosiform erythroderma, hair alterations and atopy. NS is due to SPINK5 gene mutations, which cause absent or decreased expression of the encoded protein lymphoepithelial Kazal‐type‐related inhibitor (LEKTI) in all stratified epithelia. We report a 43‐year‐old man affected with NS, who developed several squamous and basal cell carcinomas on the face, ears and scalp and papillomatous lesions of hips, groin and genitoanal area. Molecular analysis of the SPINK5 gene revealed homozygosity for the recurrent mutation c.238dupG. Human papillomavirus (HPV) DNA detection and genotyping on patient skin carcinomas and hyperplastic lesions found betapapillomavirus DNA in 10 of 12 (83%) carcinomas and in a hip papilloma, with multiple betapapillomavirus types being identified. Immunohistochemistry showed upregulated expression of p16INK4a protein in nine of 12 (75%) patient carcinomas, in line with findings reported in HPV‐related cancers. LEKTI and filaggrin immunostaining was strongly decreased in patient skin. A published work search for NS cases with skin cancers and HPV infection identified 15 NS patients, five of them showing mucosal or cutaneous HPV infection. Overall, our results confirm the increased susceptibility to skin carcinomas of some NS patients and provide further evidence of an association between HPV and non‐melanoma skin cancers in NS. The highly impaired skin barrier function, hallmark of NS, could facilitate HPV infection, in turn increasing the risk for cancer development.
Enhancement of Crystallization Processes by Power Ultrasound: Current State‐of‐the‐Art and Research Advances
Authors: Zhang Zi , Sun Da‐Wen , Zhu Zhiwei , Cheng Lina 
Published: April 2015

AbstractPower ultrasound‐assisted crystallization, which is also called sonocrystallization, is a novel and effective method for enhancing crystallization processes compared to conventional processes. In both supercooled and supersaturated crystallization, power ultrasound can accelerate the nucleation rate and better control the formation and growth of crystals. Due to its high efficiency, power ultrasound has been applied in many fields. In this review, studies published in recent years on effects of power ultrasound in both supercooled and supersaturated crystallization processes are discussed, with focus on the widely accepted crystallization mechanism and modeling. The applications of power ultrasound in liquid ice crystallization, ice cream manufacture, fruit and vegetable preservation and sugar and food supersaturated crystallization are summarized, and challenges and trends for further development of the technology are presented.
Influences of Operating Parameters on the Formation of Furan During Heating Based on Models of Polyunsaturated Fatty Acids
Authors: Shen Mingyue , Liu Qian , Jiang Yujie , Nie Shaoping , Zhang Yanan , Xie Jianhua , Wang Sunan , Zhu Fan , Xie Mingyong 
Published: April 2015

AbstractFuran, a possible carcinogen, is commonly produced by thermal processing in a number of heated foods. The existence of furan levels in foods has attracted considerable attention worldwide. Recent research of furan in food has focused on the possible influences of operating parameters on the furan formation during heat processing. The aim of our study was to investigate the impacts of multiple factors (pH, temperature, heating time, ferric, and glutamic acid) on furan formation using linolenic and linoleic acids‐based model systems in which furan was analyzed by headspace gas chromatography–mass spectrometry (HS‐GC–MS). The results revealed that the content of furan increased rapidly when the heating temperature was elevated, with the highest levels of furan in neutral buffer solutions, the furan levels were also found to be related to heating time in all model systems. Ferric promoted furan formation from polyunsaturated fatty acids, conversely glutamic acid with an optimum concentration suppressed the furan formation. The minimal level of furan in foods during thermal treatment could be achieved via adding furan formation suppressors, and/or avoidance of furan forming promoter.
Navy Bean Flour Particle Size and Protein Content Affect Cake Baking and Batter Quality1
Authors: Singh Mukti , Byars Jeffrey A. , Liu Sean X. 
Published: April 2015

AbstractWhole navy bean flour and its fine and coarse particle size fractions were used to completely replace wheat flour in cakes. Replacement of wheat flour with whole bean flour significantly increased the protein content. The protein content was adjusted to 3 levels with navy bean starch. The effect of navy bean flour and its fractions at 3 levels of protein on cake batter rheology and cake quality was studied and compared with wheat flour samples. Batters prepared from navy bean flour and its fractions had higher viscosity than the cake flour. Reducing the protein content by addition of starch significantly lowered the viscosity of cake batters. The whole navy bean flour and coarse bean fraction cakes were softer than cakes made with wheat flour but had reduced springiness. Principal component analysis showed a clear discrimination of cakes according to protein. It also showed that low protein navy bean flour cakes were similar to wheat flour cakes. Navy bean flour with protein content adjusted to the level of cake (wheat) flour has potential as a healthy alternative in gluten‐free cakes.
Rapid Detection of Melamine in Milk Using Immunological Separation and Surface Enhanced Raman Spectroscopy
Authors: Li Xiyuan , Feng Shaolong , Hu Yaxi , Sheng Wei , Zhang Yan , Yuan Shifang , Zeng Haishan , Wang Shuo , Lu Xiaonan 
Published: April 2015

ABSTRACTWe integrated immunological separation and surface‐enhanced Raman spectroscopy (SERS) to detect melamine in milk. Antimelamine was produced by New Zealand white rabbits following the injection with melamine hapten‐ovalbumin immunogen. Melamine was separated from milk by binding to the converted protein G‐antimelamine complex. After releasing antimelamine and melamine from the complex, the eluents were deposited directly onto the silver dendrite SERS‐active substrate for spectral collection. Multivariate statistical analysis including unsupervised principal component analysis and supervised soft independent modeling of class analogy validated the feasibility of applying this method to detect trace levels of melamine in milk. The limit of detection can be as low as 0.79×10–3 mmol/L. The overall analysis can be completed in 20 min, thus, it is a high‐throughput technique to screen for melamine in milk samples.
Combined Application of Antibrowning, Heat Treatment and Modified‐Atmosphere Packaging to Extend the Shelf Life of Fresh‐Cut Lotus Root
Authors: Son Jihye , Hyun Jeong‐Eun , Lee Jo‐Won , Lee Sun‐Young , Moon BoKyung 
Published: April 2015

AbstractThis work aimed to determine the effects of different concentrations of antibrowning treatments (that is, distilled water [DW], 1% ascorbic acid [AA], 0.5% chamomile [CM], and 1% AA + 0.5% CM) and heat‐treatment (55 °C for 45 s) combined with packaging under 4 different modified‐atmosphere gas compositions (that is, air, vacuum, 100% CO2, 50% CO2/50% N2) on the quality and microbiological characteristics of fresh‐cut lotus root. The quality characteristics (that is, color, weight loss, texture, pH, polyphenoloxidase activity, and total phenolic content) of the AA + CM‐dipped sample in 100% CO2 packaging were maintained significantly better than those of the other samples (P < 0.05). The microbiological counts observed in the DW‐dipped sample during storage were higher than those of the AA, CM, and AA + CM samples, and heat‐treatment retarded the microbiological deterioration of fresh‐cut lotus root. Therefore, the results revealed that dipping in an antibrowning treatment (AA + CM), and 100% CO2 MAP with heat treatment effectively extend the shelf life of fresh‐cut lotus root to 21 d at 5 °C.
Quantifying wildlife‐watching ecotourism intensity on an endangered marine vertebrate
Authors: Schofield G. , Scott R. , Katselidis K. A. , Mazaris A. D. , Hays G. C. 
Published: April 2015

AbstractHere, we show how seasonal changes in animal density drive strategic shifts in the activities of wildlife‐watching operators. These shifts result in high viewing intensity when animal densities are low, highlighting the need for modifications to existing wildlife‐watching guidelines. We used the endangered loggerhead sea turtle Caretta caretta as a model species that exhibits staggered departure from an important breeding area (Zakynthos, Greece, Mediterranean) over a 2‐month period (July to August) when tourism is at a peak, to investigate changes in wildlife‐watching strategies, zoning effectiveness and voluntary guideline compliance over time. We used a combination of direct land‐based observations, global positioning system tracking (of wildlife‐watching vessels and turtles) and models. The modelled number of turtles present in the breeding area decreased from > 200 in July to < 50 in August, while the intensity of turtle‐viewing increased from a mean 1.5 to 6.1 wildlife‐watching vessels per turtle‐viewing event (i.e. concurrent and consecutive vessels observing a single turtle) over the same period, respectively. During this period, the wildlife‐watching strategy changed and compliance to guidelines reduced (exacerbated by recreational vessels). However, wildlife‐watching activity was limited to a highly restricted 0.95‐km2 nearshore area, overlapping with just 9.5% of the core habitat area used by turtles. Our results have broad implications (whale watching etc.) by showing the importance of taking the number of animals available for viewing into consideration when assessing wildlife‐watching activity and when designing viewing guidelines, particularly for populations where numbers noticeably fluctuate.
Current knowledge of the subfamily Anacharitinae (Hymenoptera: Figitidae) in the Australasian region
Authors: Mata‐Casanova Noel , Selfa Jesús , Pujade‐Villar Juli 
Published: April 2015

AbstractA revision of the Anacharitinae material from Australia and New Zealand deposited in the Natural History Museum of London and material from Papua New Guinea deposited in the Muséum National d'Histoire Naturelle of Paris was conducted. The ranges of the previously known described Anacharis zealandica Ashmead and Xyalaspis victoriensis New are expanded. A new Australasian species of Anacharis Dalman, Anacharis tasmaniae sp. nov., is described, and the genus Aegilips Haliday is cited for the first time in the region, with the description of Aegilips papuensis sp. nov. The biology and distribution patterns of Australasian anacharitines are discussed.
Stronger T‐Cell Alloreactivity and Diminished Suppressive Capacity of Peripheral Regulatory T Cells in Infertile Women Undergoing In Vitro Fertilization
Authors: Lashley Lisa E.E.L.O. , van der Keur Carin , van Beelen Els , Schaap Rowena , van der Westerlaken Lucette A.J. , Scherjon Sicco A. , Claas Frans H.J. 
Published: April 2015

ProblemIncreasing evidence suggests modulation of the maternal immune response to be essential for successful pregnancy. We studied the immunophenotypic profile and function of peripheral blood T lymphocytes in infertile women undergoing in vitro fertilization (IVF) and fertile control population.MethodWe collected peripheral blood mononuclear cells (PBMC) from infertile patients with recurrent implantation failure (RIF), infertile patients with successful IVF (IVFs), and normal fertile women. Cells were phenotypically analyzed, and the proliferative response and cytokine production were studied in mixed lymphocyte cultures (MLC), using lymphocytes of the own partner, or a third‐party male as stimulators cells. To examine the suppressive capacity of regulatory regulatory T cells (Tregs), we performed MLC studies with a CD45+ fraction depleted for CD4+CD25bright T cells.ResultsNo significant differences in proportions of subsets of circulating T lymphocytes were observed. The proliferative allo‐immune response of PBMC of IVF women (RIF and IVFs) was significantly higher, with higher production of T‐helper cells (Th1) and Th2 cytokines, compared to the fertile women. This difference in proliferation and cytokine production was associated with a diminished suppressive capacity of Tregs in these women.ConclusionThe higher allo‐immune response of the IVF women compared to fertile women might be the result of a diminished suppressive capacity of Tregs and emphasizes the important role of Tregs during conception.
Expression of CCL22 and Infiltration by Regulatory T Cells are Increased in the Decidua of Human Miscarriage Placentas
Authors: Freier Christoph P. , Kuhn Christina , Rapp Moritz , Endres Stefan , Mayr Doris , Friese Klaus , Anz David , Jeschke Udo 
Published: April 2015

ProblemRegulatory T cells (Treg) are a T‐cell subpopulation with suppressive capacities, specifically attracted by CCL22. We aimed to investigate whether CCL22 is expressed in human placentas and whether its presence, together with Treg infiltration, is associated with miscarriage conditions.Method of studyParaffin samples were stained for CCL22 and for the Treg‐specific transcription factor FoxP3. Expression levels were evaluated in a semi‐quantitative manner. Double immunofluorescence was used for the identification of CCL22‐producing cells.ResultsIn all placentas, trophoblasts expressed CCL22. Interestingly, expression in the decidua was only observed in miscarriage conditions. Maternal stromal cells expressed CCL22. Correlation with a higher presence of Treg in the decidua of abortive tissues was observed.ConclusionOur results demonstrate that CCL22 is expressed in human placenta. Decidual expression was only observed in miscarriage conditions and correlates with Treg infiltration. Thus, CCL22 plays a role in human pregnancy and may occur as a negative feedback response to pro‐inflammatory events during miscarriage conditions.
Supervisor volume affects oncological outcomes of trainees performing open radical prostatectomy
Authors: O'Kane Dermot , Papa Nathan , Lawrentschuk Nathan , Syme Rodney , Giles Graham , Bolton Damien 
Published: April 2015

AbstractBackgroundThe relationship between biochemical failure (BF) rate and surgeon experience following open radical prostatectomy (ORP) has been well established, but BF when ORP is performed by urology trainees who are supervised by urologists of differing volume has not. We aimed to compare the oncological outcomes from ORP when a urology trainee as primary operator and is supervised by a high‐ or low‐volume consultant urologist.MethodsUsing a centralized whole of population dataset, created through the Victorian Radical Prostatectomy Registry, patients were classified as either those where a consultant was the primary operator, a urology trainee was the primary operator and supervised by a high‐volume consultant or those where a urology trainee was supervised by a low‐volume consultant. BF‐ and prostate cancer (PCa)‐specific mortality was compared between these latter two groups and the consultant‐only group.ResultsWe found BF‐ and PCa‐specific mortality rate to be poorer when ORP was performed by a urology trainee supervised by a low‐volume consultant compared with consultant‐led surgery (hazard ratio (HR) = 1.33, P = 0.022; subhazard ratio (SHR) = 2.31, P = 0.010, respectively). When a urology trainee, as primary operator, was supervised by a high‐volume consultant, there was no statistical difference in BF‐ or PCa‐specific mortality rate following ORP compared with consultant‐led surgery (HR = 1.19, P = 0.234; SHR = 1.53, P = 0.346, respectively). There was a trend evident with decreasing supervisor volume leading to worse oncological and mortality outcomes for trainee‐led cases.ConclusionThis study demonstrates the value of high‐volume and fellowship‐trained urologists in performing and teaching ORP. As outcomes are increasingly scrutinized with audits, the best strategy for clinicians to maintain standards and optimal patient outcomes is to understand these elements and direct trainees to appropriate centres for training and fellowships.