bluuebunny/crossref_metadata_2025_split huggingface dataset:
Repetitive combined doses of bacteriophages and gentamicin protect against Staphylococcus aureus implant-related infections in Galleria mellonella
Authors: Mannala Gopala K. , Rupp Markus , Walter Nike , Youf Raphaelle , Bärtl Susanne , Riool Martijn , Alt Volker 
Published: August 2024

AimsBacteriophages infect, replicate inside bacteria, and are released from the host through lysis. Here, we evaluate the effects of repetitive doses of the Staphylococcus aureus phage 191219 and gentamicin against haematogenous and early-stage biofilm implant-related infections in Galleria mellonella.MethodsFor the haematogenous infection, G. mellonella larvae were implanted with a Kirschner wire (K-wire), infected with S. aureus, and subsequently phages and/or gentamicin were administered. For the early-stage biofilm implant infection, the K-wires were pre-incubated with S. aureus suspension before implantation. After 24 hours, the larvae received phages and/or gentamicin. In both models, the larvae also received daily doses of phages and/or gentamicin for up to five days. The effect was determined by survival analysis for five days and quantitative culture of bacteria after two days of repetitive doses.ResultsIn the haematogenous infection, a single combined dose of phages and gentamicin, and repetitive injections with gentamicin or in combination with phages, resulted in significantly improved survival rates. In the early-stage biofilm infection, only repetitive combined administration of phages and gentamicin led to a significantly increased survival. Additionally, a significant reduction in number of bacteria was observed in the larvae after receiving repetitive doses of phages and/or gentamicin in both infection models.ConclusionBased on our results, a single dose of the combination of phages and gentamicin is sufficient to prevent a haematogenous S. aureus implant-related infection, whereas gentamicin needs to be administered daily for the same effect. To treat early-stage S. aureus implant-related infection, repetitive doses of the combination of phages and gentamicin are required.Cite this article: Bone Joint Res 2024;13(8):383–391.
Trend and determinants of minimum dietary diversity consumption change among children aged 6–23 months in Ethiopia from 2011 to 2019: A multivariate decomposition analysis
Authors: Endawkie Abel , Asmare Lakew , Alemu Hiwot Tadesse , Geberu Demiss Mulatu , Hagos Asebe , Jejaw Melak , Abera Kaleab Mesfin , Tiruneh Misganawu Guadie , Demissie Kaleb Assegid , Tsega Yawkal , Yeshambel Belay Adina , Negash Wubshet Debebe , Workie Amare Mesfin , Yohannes Lamrot , Getnet Mihret , Worku Nigusu 
Published: August 2024

Background
Sustainable Development Goals 2 target 2.2 aimed to end all forms of malnutrition by 2030. However, the prevalence of inadequate minimum dietary diversity (MDD) is high in Ethiopia and the evidence of trends and determinants of MDD consumption change among children over time is limited. Therefore, this study aimed to determine trends and determinants of MDD consumption change among children aged 6 to 23 months in Ethiopia from 2011–2019 Demographic and Health Survey (DHS) data.

Method
The study used the data on nationally representative weighted samples of 6,971, 7,467, and 3,154 children aged 6–23 months from the 2011, 2016, and 2019 rounds of the DHS. Trend and Multivariate Decomposition analysis was conducted to determine MDD consumption change from 2011–2016, and 2016–2019 into two components: one that was explained by differences in the level of the determinants (endowment), and the other component was explained by differences in the effect of the covariates on the outcome (coefficient effects).

Result
The trends analysis showed that adequate MDD consumption significantly increased from 2% to 10.41% from 2011 to 2016 but decreased from 10.41% to 7.11% from 2016 to 2019 in Ethiopia. The compositional and behavioral change factors like maternal age, occupational status of parents, sex of the household head, wealth index, residence, and sex of child statistically contributed to changes in MDD consumption from 2011 to 2016, and from 2016 to 2019 at p-value <0.05.

Conclusion
The trend of minimum dietary diversity consumption among children aged 6 to 23 months in Ethiopia increased from 2011–2016 and decreased from 2016–2019 in the last decade. The study revealed that the changes in behavioral response and population composition contributed to MDD consumption change among children in Ethiopia. The finding highlights the urgent need for targeted interventions and policies to address the issue of MDD consumption change among young children due to population structure changes like wealth status, residence, and behavioral response related to employment, household head, and sex of the child in Ethiopia. Therefore, efforts should be geared to reduce poverty and improve maternal employment status, particularly for women, by producing equitable economic opportunities.
Spatial distribution of Tetraclinis articulata (Vahl) Mast. formations in north- western Algeria
Authors: El Mechri Omar , Belgherbi Benamar , Benaradj Abdelkrim , Berkane Ibrahim 
Published: August 2024

Tetraclinis articulata (Vahl) Mast., syn. Thuja articulata Vahl, is mainly confined to the south-western Mediterranean region and considered to be endemic to North Africa (Morocco, Algeria, and Tunisia). This tree species is experiencing a significant regression of its range, in some cases irreversible. Currently, it is classified as an Ibero-Mauritanianelement. Our objective was to study the dynamics of land cover and even the possibilities of rehabilitation of this species. The forest formation based on Tetraclinis articulata, represented in this study by the areas known as Oued Fergoug and Béni-Khenies forests, has been subject to both regressive and progressive dynamics. An analysis and mapping of the vegetation over 48 years (1975-1994-2022) revealed that the forest cover, with an initial surface area of 3680.47 ha (61.36%) deteriorated dramatically in 1994 as a result of repeated fires and the drought that prevailed then, to 122.65 ha (2.04%) – a truly alarming situation. However, in 1994-2022 this forest formation experienced a significant biological recovery, so that the estimated vegetation cover is now 4292.64 ha (71.56%), with the appearance of dense woodland in an area of 13.18 ha.
New records of protected, threatened, and rare vascular plant species in the Lower Bug Valley (eastern Poland)
Authors: Szulc Adam Piotr , Wiśniewski Marcin 
Published: August 2024

We present new localities and verified published records of protected, rare, and threatened vascular plant species in the Mazovia region, mostly in the left-bank part of the Lower Bug Valley (Dolina Dolnego Bugu). Some localities are in the Wołomin Plain (Równina Wołomińska) and the Siedlce Plateau (Wysoczyzna Siedlecka). The analysed species occur in various natural and semi-natural habitats, such as xerothermic and sandy grasslands, floodplain meadows, wetlands, bogs, and forests. Data were collected during field research carried out in 2021-2023. In the left-bank part of the Lower Bug Valley, 45 species of protected plants were recorded, but also red-listed or regionally rare plants (90 species in total). They include 16 species are under strict protection, 29 under partial protection, and 35 species are rare in the region. Some of the localities described earlier by other authors were found again or verified. In the Lower Bug Valley, there are almost all plant associations known from Mazovia, including the extremely valuable boreal Sphagno girgensohnii-Piceetum, protected in the “Jegiel” reserve. There are also oak forests on the edge of the Siedlce Plateau. The valleys of the Bug and its tributaries are dominated by areas of cultivation, arable fields, meadows, and forests. Some species considered to be common in other regions are rare in the Bug river valley, e.g. Hepatica nobilis, Asarum europaeum, Isopyrum thalictroides. This is because their habitats are sparse or degraded. However, some other species, rare in other regions, are common in the study area, e.g. Allium angulosum, Euphorbia lucida, and Hierochloë odorata on floodplain meadows, Salvinia natans in oxbow lakes, and Arctostaphylos uva-ursi in pine forests and sandy grasslands. The only locality of Blechnum spicant in this part of Mazovia was found in this study. The species is characteristic of montane forests and fir-spruce forests. Two localities of Diphasiastrum tristachyum were recorded, in typical habitats of this species: heaths formed after forest fires.
State and contours of research on roselle (Hibiscus sabdariffa L.) in Africa
Authors: El Bilali Hamid 
Published: August 2024

Abstract
Roselle (Hibiscus sabdariffa L.) – also called sorrel, Bissap or Karkadeh – is believed to be native to Africa. Research is needed to set a solid foundation for the development of roselle in the continent. Therefore, this article presents an analysis of the research landscape on roselle in Africa; it covers bibliographical metrics, the geography of the research, and the topics addressed in the scholarly literature about roselle. The systematic review drew upon 119 eligible articles identified through a search carried out on the Web of Science in March 2024. The research field is not well-established; the number of publications on roselle in Africa is limited, indicating an unstable and inconsistent interest. The research field is multidisciplinary but appears to focus more on biological sciences than social sciences and economics. The research geography is not balanced, with more than half of all studies on roselle in Africa conducted in just five countries, viz. Nigeria, Egypt, Sudan, Ghana, and Senegal. The content analysis suggests that roselle holds the potential to contribute to food and nutrition security and the well-being of the populations. It can not only contribute to agricultural development but also to addressing many challenges the continent faces. Research is needed to unlock its potential. Future research should pay more attention, inter alia, to the relationships between roselle and environmental issues (e.g. climate change), social and economic aspects (e.g. livelihoods), and agronomy (cf. fertilization, pest management, irrigation). Given that roselle is grown across Africa, collaboration among African countries should also be encouraged.
Copper-Based Nanomaterials for Image-Guided Cancer Therapy
Authors: Xu Haonan , Guo Zhili , Li Mingjie , Chaves Hellíada Vasconcelos , Pinto Vicente de Paulo Teixeira , Filho Gerardo Cristino , Du Meng , Bezerra Mirna Marques 
Published: August 2024

Abstract
Cancer is a significant disease that poses a major threat to human health. Image-guided cancer therapy refers to a series of medical procedures that use imaging technology to precisely locate and treat cancer. Combining the dual characteristics of medical images and functional nanomaterial (NM) drug carriers, various integrated diagnosis and treatment probes have been developed for in vivo dynamic monitoring and therapeutic effect evaluation of drugs based on medical imaging. Copper (Cu)-based NMs have emerged as valuable products of nanotechnology due to their unique physicochemical properties, which are influenced by factors, such as size, shape, and surface properties. In the field of imaging, Cu-based NMs offer a combination of desirable characteristics, including fluorescence emission, contrast enhancement, and radiolabeling stability. These properties form the foundation for a wide range of imaging modalities. In addition, Cu-based NMs can be used as a carrier for diagnostic or therapeutic drugs and the synergistic effect of multiple therapeutic modalities can be realized by doping multiple transition metals into the heterostructures. These properties have become an important basis for imaging-guided therapy with Cu-based NMs. In this review we introduce biocompatible Cu-based NMs for image-guided cancer therapy and provide an overview of the promising outcomes in biomedical research.
РОЛЬ ЦИФРОВІЗАЦІЇ КРЕАТИВНИХ ІНДУСТРІЙ У ВОЄННИЙ ЧАС І В ПЕРІОД ПОВОЄННОГО ВІДНОВЛЕННЯ УКРАЇНИ
Authors: ДУЛЬСЬКА Ірина 
Published: August 2024

Досліджено релевантність оцінки глибини цифровізації галузей креативних індустрій (КІ) України для розробки заходів з принципового збільшення гнучкої зайнятості й доходів бізнесу і населення в КІ, які можуть частково замістити втрати матеріальних, людських і виробничих ресурсів під час війни і в період повоєнної відбудови країни.
Встановлено, що мають місце методологічні відмінності між дефініціями КІ світових інституцій (ЮНКТАД), країнових переліків і законодавчо визначеним у 2019 р. в Україні переліком галузей КІ, що потребує актуалізації, оскільки не враховує глибини формування інформаційного суспільства й стрімкого переходу соціально-економічної системи від постіндустріальної до неоіндустріальної фази розвитку, поштовх якому надали пандемія COVID-19 і повномасштабна війна в Україні.
Розвитку цифровізації КІ бракує засобів статистичного моніторингу, оскільки переважну більшість галузей КІ не включено до статистичних обстежень Державної служби статистики України; не моніториться впровадження таких ІКТ-інновацій, як штучний інтелект, що масово запроваджуються в КІ (нейромережі, Chat-GPT тощо), блокчейн (NFT), що суперечить підходам ЄС щодо моніторингу цифровізації соціально-економічних систем як для країни – кандидата на членство в ЄС. Здебільшого для дослідження цифровізації КІ доступний лише івент-метод аналізу. Через проблеми статистики важко оцінити місце КІ в зовнішньоекономічній діяльності. Не налагоджено екосистему комплаєнсу нерегулярного підприємництва в КІ при розміщенні інтелектуального продукту і послуг у так званих нових медіа на зарубіжних відеохостингових платформах і в Інтернеті щодо податків, авторського права та інтелектуальної власності. Спроби запровадити адекватні інструменти контролю за сплатою податків з доходів фрілансерів виявилися малоефективними. Законопроєкт щодо реєстрації і оподаткування нерегулярних видів діяльності, у тому числі в КІ, досі не прийнято.
Запропоновано механізми сприяння розвитку масових КІ від бізнесу, держави, органів місцевого самоврядування, інститутів громадянського суспільства тощо.
Geolocalización de municipios idóneos en Colombia para instalar calentadores solares de agua por medio de un análisis multicriterio sustentable
Authors: Marín Quiroga Francisco , Solís Cháves Juan Sebastián , Medina Gamba Andrés Felipe 
Published: August 2024

Un factor que ha llevado a un aumento en el uso de fuentes energéticas basadas en la utilización del sol, el viento, el agua o la biomasa (denominadas fuentes de energía renovables) es la necesidad de minimizar la aceleración del calentamiento. Con esta preocupación ambiental se han establecido diferentes estrategias enmarcadas dentro del enfoque del Desarrollo Sustentable haciendo necesaria una evaluación adecuada de los sitios idóneos para la utilización óptima de estos recursos. El presente se enmarca en la temática de las Fuentes No Convencionales de Energía Sustentable, proponiendo una revisión y simulación, teniendo en cuenta diferentes fuentes de información estadística para la identificación y determinación de los municipios idóneos en Colombia para el aprovechamiento del calor solar con el fin de instalar sistemas de energía solar térmica en función de las perspectivas técnicas, económicas y socioambientales (perspectivas del desarrollo sustentable). El estudio se realiza con el uso combinado de Sistemas de Información Geográfica y la Toma de Decisiones MultiCriterio. En particular, se aplica uno de los métodos estadísticos multicriterio, concretamente el Proceso de Jerarquía Analítica (Analytic Hierarchy Process - AHP) y la técnica de las Sumas Ponderadas (Rank Sum) con la estrategia de evaluación conocida como Combinación Lineal Ponderada (Weighted Linear Combination –WLC). En el análisis se considera el modelo digital de elevación para descartar municipios de clima cálido-templado en Colombia.
Compensación de factor de potencia y desbalance de carga mediante un inversor fotovoltaico seguidor de red
Authors: Osorio Silva Fausto , Mantilla Villalobos María A. , Petit Suárez Johann F. 
Published: August 2024

Los sistemas de generación distribuida conectados a la red mediante inversores juegan un rol importante en los sistemas eléctricos modernos de distribución. Funcionalidades adicionales para mejorar la calidad de la energía y dar soporte a la red pueden ser incorporadas a los inversores de potencia, siendo este un campo de investigación y desarrollo de gran relevancia en la actualidad. Teniendo en cuanta esta tendencia mundial en donde los sistemas de generación distribuida han aumentado considerablemente su participación en la matriz energética, los códigos de red se están actualizando constantemente, y la operación y control de los dispositivos electrónicos de potencia deben considerar las dinámicas actuales que conlleven a un escenario de transición seguro y confiable. En este contexto, este trabajo presenta un sistema de control para un inversor fotovoltaico trifásico operando en modo de seguidor de red, el cual permite incorporar funcionalidades de corrección de factor de potencia y compensación de desbalance de carga al sistema fotovoltaico. Mediante este sistema de control es posible seleccionar las componentes de potencia de la carga a compensar, las cuales definen las funcionalidades de filtrado activo a integrar al sistema fotovoltaico con el fin de mejorar la calidad de la energía en el sistema de distribución. La operación del sistema fotovoltaico es evaluada mediante simulaciones en la plataforma Matlab/Simulink, considerando una carga lineal desbalanceada y cuatro diferentes modos de operación del inversor según las componentes de potencia de la carga a compensar. Los resultados obtenidos permiten verificar el cumplimiento de los objetivos de control y evidencian ventajas y desventajas de los diferentes modos de operación considerados para el inversor de potencia.
Janusz Korczak's work on child protection and its contemporary implications
Authors: Godawa Grzegorz 
Published: August 2024

AbstractJanusz Korczak's pedagogy is focused on the child and its needs. The need to protect the child from abuse in its environment is especially important. The Polish pedagogue spoke out against this kind of abuse in his publications as well as in his educational activity. In 1912, together with Stefania Wilczyńska, he founded an orphanage in Warsaw. In that house, children's rights were protected and good conditions were created for their multifaceted development. During World War II, the house was closed down and its inhabitants were sent to a Nazi extermination camp. Janusz Korczak accompanied the exiled children and lost his life with them. Although he failed to protect his pupils from death, he showed that protection is a fundamental right of the child. It is a right which should be universally respected. The contemporary implications of Janusz Korczak's thoughts and activities can be observed in legal and pedagogical initiatives for child protection. Its scope should be constantly adapted to the current threats and changing conditions of social life. Korczak's call to respect the rights of the child which protect its dignity and freedom is still relevant.
CULTURA MAKER, TECNOLOGIAS ASSISTIVAS E INTERNET DAS COISAS (IoT): APERFEIÇOAMENTO E VALIDAÇÃO DE PROTÓTIPO DE BAIXO CUSTO PARA ACESSIBILIDADE DE PESSOA COM DEFICIÊNCIA
Authors: Silva Nicacio Erikson Pedro , Silva Oliveira Gabriel , Gomes Araújo Hector Hêndrio , Souza Soares Emiliana , Araujo da Silva Humberto 
Published: August 2024

Baseado no ponto de vista das tecnologias assistivas e Internet das Coisas (IoT), o presente trabalho tem como objetivo apresentar o desenvolvimento de um protótipo de uma tecnologia assistiva composta por uma bengala eletrônica e um aplicativo para smartphone que visa contribuir para a acessibilidade de deficientes visuais sob a perspectiva de práticas de cultura maker. Quando associado ao piso tátil, o uso do protótipo torna possível a identificação dos setores de um recinto pelo deficiente visual, através de avisos audíveis transmitidos para o usuário por meio de seu smartphone mediante a detecção de um determinado cartão de identificação, ou tag, presente no piso tátil. Para a construção dessa tecnologia assistiva proposta, foi empregado o microcontrolador ESP 32 e a ferramenta tecnológica denominada Identificação por Radiofrequência (RFID – do inglês Radio Frequency Identification). Dessa forma, o protótipo comunica-se com um aplicativo via conexão bluetooth, de modo que o ESP 32 encaminha para o usuário a informação referente a sua localização com base na identificação realizada por um leitor RFID quando este detecta um cartão de identificação RFID. Metodologicamente, trata-se de uma pesquisa bibliográfica e experimental, considerando literaturas acerca dos conceitos e tecnologias abordadas neste trabalho. O projeto continua em andamento, porém com grau avançado na realização de testes práticos de usabilidade, visando seu aprimoramento. Os resultados parciais já assinalam a viabilidade do protótipo e a relevância de seus benefícios, inclusive para utilização em contexto escolar, com perspectivas futuras de novas pesquisas.
Informativity, information status and the accessibility of indefinite noun phrases
Authors: von Heusinger Klaus , Weeber Frederike , Hoek Jet , Brocher Andreas 
Published: August 2024

In discourse processing, speakers collaborate toward a shared mental model by introducing discourse referents and picking them up with the adequate linguistic forms. Discourse referents compete with each other with respect to their prominence and their accessibility for pronouns. This study focuses on transitive sentences with proper names as subjects and indefinite noun phrases as second arguments, typically direct objects. An ambiguous pronoun in the subsequent sentence may access either referent of the first sentence. Various factors have been shown to influence pronoun resolution, including informativity (how informative is the phrase in which the referent is introduced? E.g., the waiter vs. the waiter at the entrance) and information status (is the referent given or new in the context?). While both factors have been independently shown to increase referent accessibility, our visual-world eye-tracking experiment shows an original and quite unexpected effect: informativity and information status interact when it comes to the accessibility of indefinite noun phrases: a higher degree of informativity increases accessibility when a referent is brand-new, but surprisingly decreases accessibility when a referent is inferred. We discuss a potential explanation for this surprising pattern in terms of a mismatch between the denotational type of the indefinite and the type required by the modification. We conclude that indefinites strongly interact with additional semantic, contextual and communicative parameters in establishing their referents.