bluuebunny/crossref_metadata_2025_split huggingface dataset:
A review of sleep deprivation studies evaluating the brain transcriptome
Authors: Elliott Alisa S , Huber Jason D , O’Callaghan James P , Rosen Charles L , Miller Diane B 
Published: December 2014

Abstract
Epidemiological studies show a positive association between adequate sleep and good health. Further, disrupted sleep may increase the risk for CNS diseases, such as stroke and Alzheimer’s disease. However, there has been limited progress in determining how sleep is linked to brain health or how sleep disruption may increase susceptibility to brain insult and disease. Animal studies can aid in understanding these links. In reviewing the animal literature related to the effects of sleep disruption on the brain, we found most of the work was directed toward investigating and characterizing the role of various brain areas or structures in initiating and regulating sleep. In contrast, limited effort has been directed towards understanding how sleep disruption alters the brain’s health or susceptibility to insult. We also note many current studies have determined the changes in the brain following compromised sleep by examining, for example, the brain transcriptome or to a more limited extent the proteome. However, these studies have utilized almost exclusively total sleep deprivation (e.g., 24 out of 24 hours) paradigms or single short periods of limited acute sleep deprivation (e.g., 3 out of 24 hours). While such strategies are beneficial in understanding how sleep is controlled, they may not have much translational value for determining links between sleep and brain health or for determining how sleep disruption may increase brain susceptibility to insult. Surprisingly, few studies have determined how the duration and recurrence of sleep deprivation influence the effects seen after sleep deprivation. Our aim in this review was to identify relevant rodent studies from 1980 through 2012 and analyze those that use varying durations of sleep deprivation or restriction in their effort to evaluate the effects of sleep deprivation on the brain transcriptome and to a more limited extent the proteome. We examined how differences in the duration of sleep deprivation affect gene and protein expression to better understand the full consequences of repeated sleep disruption on the brain. Future research needs to consider and emphasize how the type and extent of the sleep deprivation exposure impacts the conclusions reached concerning the influence of sleep disruption on the brain.
We identified relevant studies between 1980 and 2012 by searching the electronic databases of PubMed, Medline (Ovid), Embase (Ovid), and Web of Science using the terms “sleep” AND “disrupt”, “deprivation”, “restrict”, “fragment”, “loss”, “disturb”, “disorder”, “dysfunction”, “brain”, “cortex”, striatum”, hypothalamus”, “hippocampus”, “gene”, “protein”, “genomics”, “proteomics”, “polymerase chain reaction”, “pcr”, “microarray”, “molecular”, “rodent” “rat”, “rats”, “mouse”, “mice”. All searches were limited to rodent studies in English and the reference lists of retrieved articles were searched for additional pertinent studies.
Diesel biodegradation capacities of indigenous bacterial species isolated from diesel contaminated soil
Authors: Palanisamy Nandhini , Ramya Jayaprakash , Kumar Srilakshman , Vasanthi NS , Chandran Preethy , Khan Sudheer 
Published: December 2014

Abstract
Petroleum based products are the major source of energy for industries and daily life. Leaks and accidental spills occur regularly during the exploration, production, refining, transport, and storage of petroleum and petroleum products. In the present study we isolated the bacteria from diesel contaminated soil and screened them for diesel biodegradation capacity. One monoculture isolate identified by 16S rRNA gene sequence analysis to be Acinetobacter baumannii was further studied for diesel oil biodegradation. The effects of various culture parameters (pH, temperature, NaCl concentrations, initial hydrocarbon concentration, initial inoculum size, role of chemical surfactant, and role of carbon and nitrogen sources) on biodegradation of diesel oil were evaluated. Optimal diesel oil biodegradation by A. baumanii occurred at initial pH 7, 35°C and initial hydrocarbon concentration at 4%. The biodegradation products under optimal cultural conditions were analyzed by GC-MS. The present study suggests that A. baumannii can be used for effective degradation of diesel oil from industrial effluents contaminated with diesel oil.
Enantioselective Synthesis of (+)-N-(Desmethyl)dysibetaine CPb
Authors: Tanaka Kento , Sakai Michihiro , Takamizawa Satoshi , Oikawa Masato 
Published: December 2014

Abstract
The synthetic efforts to dysibetaine CPb, isolated from Micronesian marine sponge, amenable to analog synthesis are reported. Cyclopropane was constructed by a sulfonium ylide-mediated reaction and enantioselective desymmetrization was performed by methanolysis mediated by a quinine derivative. (+)-N-(Desmethyl)dysibetaine CPb was finally synthesized in 0.37% yield in total 14 steps. This is the first synthesis of the dysibetaine CPb analog.
Prospect Theory Explains Newsvendor Behavior: The Role of Reference Points
Authors: Long Xiaoyang , Nasiry Javad 
Published: December 2014

Current understanding in operations management is that prospect theory, as a theory of decision making under uncertainty, cannot systematically explain the ordering behavior observed in experiments on the newsvendor problem. We suggest this is because the newsvendor’s reference point is assumed to be the status quo, i.e., zero payoff. We propose an alternative based on newsvendor’s salient payoffs and show that prospect theory can, in fact, account for experimental results. This paper was accepted by Serguei Netessine, operations management.
Discussing the Igbo language on the Igbo Internet radio: Explicating ethnolinguistic vitality
Authors: Onuzulike Uchenna 
Published: December 2014

Abstract
There is a growing concern about the decline and possible extinction of the Igbo language. The Igbo are primarily located in the south-eastern part of Nigeria. This study analysed four interviews on Igbo Radio, an Igbo Internet radio station, to ascertain how Internet radio is being utilized in discussing the decline of the Igbo language. Drawing on ethnolinguistic vitality theory, this qualitative study triangulates four selected interviews on Igbo Radio, the website, and personal observations for the analysis. Three salient themes emerged: (1) decline and challenges of the Igbo language, (2) second-generation immigrants and the Igbo language, and (3) sustaining the Igbo language. The findings suggest that Igbo parents appear to have less vitality; as a result, they tend not to teach their children Igbo.
From digital switchover to austerity measures: A case study of the Cypriot television landscape
Authors: Nicoli Nicholas 
Published: December 2014

Abstract
In April 2013 Cyprus and the Troika (the European Commission, the European Central Bank and the International Monetary Fund) reached an agreement aimed at addressing the country’s financial imbalances by leading the Island through a series of austerity measures. This article addresses the Cypriot digital television landscape three years following digital switchover (DSO) and currently in the midst of austerity measures. The article draws on long-term historical analyses combined with discourse analysis of current policy decisions, media coverage and expert interviews with the main stakeholders. It is divided into five sections. The first situates the case study within an appropriate theoretical framework. The second sheds light on Cyprus’ turbulent history and how it has affected the development of the media sectors. Next, it offers an overview of digital television in Cyprus and highlights how the main players had positioned themselves in the market before the country sunk into a deep recession. The fourth section underlines the financial crisis and the resulting austerity measures that have affected Cyprus, especially since 2012/2013. In the fifth and final section, the work focuses on the current situation, paying particular attention to how political and market-driven agendas have collided, with the example of the digital terrestrial television (DTT) platform Velister.
The mediatization of celebrity politics through the social media
Authors: Wheeler Mark 
Published: December 2014

Abstract
This article provides an analysis of celebrity politics within the public sphere. As there has been a commodification of digital media services, the lines between politics and entertainment have been blurred. With the rise of talent shows, rolling news channels, Web 2.0 networks and user-generated online content, celebrity has become instantaneous and may be orchestrated in viral terms. Therefore, this analysis will consider how politicized celebrities (CP2s) have received a greater amount of coverage with reference to social networks such as Twitter and Facebook to associate themselves with endorsements, causes and activities. The article will provide a case study of the online dispute that occurred amongst film, television and music stars concerning Israel’s 2014 military action within Gaza. Finally, it will reflect upon whether celebrity activists’ use of the social media can reinvigorate politics or will such activity erode the political culture.
Beryl Reid Says… Good Evening: Performing queer identity on British television
Authors: White Rosie 
Published: December 2014

Abstract
Beryl Reid Says… Good Evening (1968) was a comedy revue series broadcast on BBC television in the late 1960s that showcased the talents of a renowned British character comedy performer. Beryl Reid’s career spanned music hall, variety theatre, dramatic acting, radio comedy, film and television. She was a celebrity figure from the 1950s to her death in the 1990s but never became a ‘star’ as such. Reid’s work is addressed as a form of queer performance, both in roles that reference lesbian sexuality and roles that depict eccentric femininities. This television series was one of the few attempts to showcase her talents, and it is discussed here as an example of how character comedy queers heteronormativity through its camp attention to the everyday.
Multilevel preconditioning for sparse optimization of functionals with nonconvex fidelity terms
Authors: Dahlke Stephan , Fornasier Massimo , Friedrich Ulrich , Raasch Thorsten 
Published: December 2014

Abstract
This paper is concerned with the development of numerical schemes for
the minimization of functionals involving sparsity constraints and nonconvex fidelity terms. These functionals appear in a natural way in the context of Tikhonov regularization of nonlinear inverse problems with ℓ1 penalty terms. Our method of minimization
is based on a generalized conditional gradient scheme. It is well known that these algorithms might converge quite slowly
in practice. Therefore, we propose an acceleration which is based on a decreasing thresholding strategy. Its efficiency relies on certain spectral
properties of the problem at hand.
We show that under certain boundedness and contraction conditions the resulting algorithm is
linearly convergent to a global minimizer and that the iteration is monotone with respect to the Tikhonov functional.
We study important classes of operator equations to which our
analysis can be applied. Moreover, we introduce a certain multilevel preconditioning strategy which in practice promotes the
aforementioned spectral properties for problems where the nonlinearity is a perturbation of a linear operator.
On the Piecewise Linear Exact Solution
Authors: Pogorilyi Oleksandr , Trivailo Pavel M. , Jazar Reza N. 
Published: December 2014

Abstract
In this paper we will show how the exact frequency
response of the piecewise linear vibration isolator
can be reduced to be found by solving only two transcendental
equations. Adopting a new nondimensionalization
method, the mathematical modeling of the system is presented
and the mathematics to determine the exact steadystate
response of the system is explained.
Effect of Porphyromonas gingivalis Lipopolysaccharide on Bone Marrow Mesenchymal Stem Cell Osteogenesis on a Titanium Nanosurface
Authors: Xing Helin , Taguchi Yoichiro , Komasa Satoshi , Yamawaki Isao , Sekino Tohru , Umeda Makoto , Okazaki Joji 
Published: December 2014

Background: Titanium (Ti) dental implants have been widely used for prosthetic reconstruction of dentition. Unfortunately, peri‐implantitis can result in failure of dental implant osseointegration. Lipopolysaccharide (LPS) acts as a chronic inflammatory stimulus and maintains peri‐implant inflammation, worsening the prognosis for implant osseointegration. The purpose of this study is to determine the effects of 10 M NaOH‐modified Ti surface with nanonetwork structure on the proliferation and osteogenic differentiation of rat bone marrow mesenchymal stem cells (BMMSCs) in the context of Porphyromonas gingivalis LPS exposure.Methods: Titanium disks treated with 10 M NaOH solution and control were incubated with BMMSCs and exposed to P. gingivalis LPS (0, 0.1, or 1 μg/mL). The effects of the modified nanonetwork structure on osteogenic differentiation of rat BMMSCs were evaluated in the context of different concentrations of P. gingivalis LPS exposure.Results: Rat BMMSCs on the 10 M NaOH‐modified Ti surface with nanonetwork structure had higher levels of osteogenesis‐related gene expression and significantly greater cell proliferation, alkaline phosphatase activity, and extracellular matrix deposition and mineralization than cells on the untreated Ti surfaces, in all the groups with different doses of P. gingivalis LPS exposure.Conclusion: The 10 M NaOH‐modified Ti surface with nanonetwork structure has better endotoxin tolerance under P. gingivalis LPS exposure than the non‐modified surface.
Evaluation of Biochemical Parameters and Local and Systemic Levels of Osteoactive and B‐Cell Stimulatory Factors in Gestational Diabetes in the Presence or Absence of Gingivitis
Authors: Gümüş Pınar , Özçaka Özgün , Ceyhan‐Öztürk Banu , Akcali Aliye , Lappin David F. , Buduneli Nurcan 
Published: December 2014

Background:Gestational diabetes mellitus (GDM) is defined as varying glucose intolerance, with first onset or recognition in pregnancy. This study evaluates clinical and biochemical parameters in a possible association between GDM and gingivitis.Methods:A total of 167 pregnant females was included in the study. There were 101 females with GDM and 66 females without GDM. Subgroups were created according to the presence or absence of gingival inflammation. Plaque index, bleeding on probing, and probing depth were recorded at four sites per tooth. Serum, saliva, and gingival crevicular fluid (GCF) levels of interleukin (IL)‐6, IL‐8, soluble receptor activator of nuclear factor‐kappa B ligand (sRANKL), osteoprotegerin (OPG), B‐cell activating factor (BAFF), and a proliferation‐inducing ligand (APRIL) were determined by enzyme‐linked immunosorbent assay. Data were analyzed by Kruskal‐Wallis and Mann‐WhitneyUtests and Spearman correlation analysis.Results:Age and anthropometric indices were higher in the GDM than non‐GDM group (P<0.0001). Clinical periodontal recordings, serum BAFF, IL‐8, and saliva sRANKL levels were higher in the GDM group (P<0.05). Saliva IL‐6 level was higher in the GDM with gingivitis group than non‐GDM with gingivitis group (P= 0.044). Serum and GCF BAFF (P<0.0001), serum, saliva, and GCF APRIL (P<0.0001;P<0.0001;P= 0.032, respectively), GCF OPG (P= 0.036), and serum and saliva sRANKL (P<0.0001) were higher in the GDM with gingivitis group than GDM without gingivitis group.Conclusions:The inflammatory response seems to be more pronounced in females with GDM. The observed increase in both local and systemic levels of inflammatory cytokines may suggest an interaction between gingivitis and GDM.
Development of New Kill Fluids with Minimum Sagging Problems for High Pressure Jilh Formation in Saudi Arabia
Authors: AlAbdullatif Ziad , Al-Yami Abdullah , Wagle Vikrant , Bubshait Abdulaziz , Al-Safran Ali 
Published: December 2014

Abstract
A successful kill fluid formulation for the overpressured Jilh formation has been achieved. Jilh formation is a dolomitic middle Triassic tight zone that ranges from 8,000 to 10,000 ft TVD with abnormal salt-water pressure that requires a kill fluid with a density up to 150 lb/ft3 (pcf). Addition of weighting materials such as barite (BaSO4) or hematite (Fe2O3) is needed to achieve the desired density for the kill fluid. However, maintaining high volume of solid content for barite particles (or any other weighting material) in suspension is challenging, especially for extended period of time. This phenomenon is described in the industry as static barite sag and it may lead to serious well control incidents and lost circulation.
Saudi Aramco developed a new formula for kill fluids at high range of densities up to 150 pcf using barite with manganese tetroxide (Mn3O4). No similar formulations were developed before to the best of the authors' knowledge. The properties of small particle size (D50=1 μm), spherical shape, and high specific gravity (4.95 g/cm3) of manganese tetroxide make it a good weighting material to reduce solids loading and settling compared to barite (SG= 4.20 g/cm3 and D50=20 μm). Results show that the density variation between the upper and lower section after 24 hours of vertical static condition is 5 pcf for the new formula (density= 150 pcf) compared to a variation of 13 pcf for the conventional formula that has barite only. When the drilling fluid is put in inclined static condition for 24 hours, the density variation is 6 pcf for the new formula (density= 150 pcf). However, the conventional formula showed a density variation of 17 pcf.
The experimental work in this paper involved rheological properties, thermal stability, HT/HP filtration, and static sagging. This paper also describes field cases with barite sagging in high temperature wells and method and formulation of combining manganese tetroxide and barite to formulate new kill fluid formulations for Jilh Formation in Saudi Arabia fields.
Successful DST Methodology Adopted in Highly deviated, Deep, Sour & HPHT Exploratory well: A Case Studie
Authors: Al-Ibrahim Abdulla , Al-Bader Haifa , Al-Salali Yousef , Duggriala Vidya sagar , Ayyayo Manimaran , Subban Packirisamy 
Published: December 2014

Abstract
Exploration in the state of Kuwait focuses on finding light oil and gas from deeper, HPHT and naturally fractured tight gas and condensate Jurassic Reservoirs. These reservoirs are drilled with high Oil Base Mud (OBM) densities(16-20.8ppg). The existing surface and subsurface constraints resulted in changing the proposed well location, which resulted in changing the well profile from vertical to highly deviated well. Having a deep HPHT well in highly deviated manner causes more complexity while drilling and testing the Jurassic formations. 78.2-degree angle deviated well with several side tracks and two doglegs was drilled to a depth of around 20,000-ft.(MD) to delineate the potential of the deep reservoirs. Well intervention operations were considered potentially risky due to the presence of hazardous well conditions such as HPHT and high H2S concentration. Keeping in view of well profile and hostile environments, it was very challenging task to conduct a short term well testing (STT) in these deep reservoirs.
Tractor was used in the highly deviated sections with more than 50-degree angle to record the cement quality logs with Wireline. The target formations were perforated using high temperature and high shot density TCP guns in overbalance condition using drill-pipe. Two separate Drill Stem Tests (DST) consist of tester valve, multi-cycle circulating valve, two rupture disc valves, Down-hole sampler and Down-Hole memory gauges were used to test two different deep high pressure and sour reservoirs. Using of 15K Coiled Tubing with total length of 20,000ft for well activation and stimulation assisted the well intervention during the STT.
Careful planning, proper selection of equipment & materials, detailed well test program and procedures resulted in a safe and successful testing operations in such extreme well conditions such as unconventional well profile, HPHT, and presence of H2S. For the first time in Kuwait, a highly deviated exploratory well with complete set of DST tools was successfully tested and proved significant amount of light oil and gas from a hostile reservoir.
This paper describes and discusses the challenges encountered while drilling and testing an exploratory well and the achievement of overcoming these challenges which leads to successful well testing.
Higher Recoveries and Sustained Production Following Structured Multi-Disciplinary Reviews: A Case from Offshore Nigeria
Authors: Sonde Adekoyejo Babatunde , Emesi John Chukwudi , Avu Albert A. , Oladipo Titilola 
Published: December 2014

Abstract
Getting the maximum possible recovery from existing developments safely is at the heart of the Wells Reservoirs and Facilities Management (WRFM) processes of Shell Companies. WRFM in Shell seeks to keep deferments and natural production decline rates as low as possible and optimise production in line with field WRFM philosophy (minimal pressure depletion, keeping producing GOR below a threshold, keeping well head pressure and surface vessels within a defined envelope, etc). At the foundation of this efficient WRFM lies a thorough and current understanding of the entire production system, one of the ways by which this is achieved is via a system of multi-discipline (daily, quarterly, annual and ad-hoc) reviews developed within Shell and for Wells, Reservoirs and Facilities Management to enable quick understanding of deviations and quick decision making and quick corrective actions.
These reviews are applied in the field under discussion. The King Field is located offshore Nigeria and has been operated for over a decade. Increasing water production with an attendant oil production decline is the most critical concern in the field. Good WRFM practices have therefore become more important than ever to safely and optimally produce hydrocarbons from the field.
In one reservoir, decisions and actions following from systematic reviews resulted in the restoration of production to two producers and increased production from two other producers by artificial lift opportunity identification and execution in the wells with the following benefits: Increase in reservoir ultimate recovery.Optimal use of installed FPSO capacity.
Similar applications of structured multi-discipline reviews to developed reservoirs have the potential to improve the recovery efficiency of these reservoirs using "common place" technologies such that a small increase in recovery factors could cumulatively result in an immense increase in production from developed fields at minimal expenditures.