bluuebunny/crossref_metadata_2025_split huggingface dataset:
Flexible hollow Ni/Al2O3 fibers: A sustainable and reusable catalyst for efficient dry reforming of methane
Authors: Yan Huihui , Wang Kun , Zhao Liping , Zhang Peng , Chen Han , Liu Jing , Gao Lian 
Published: July 2024

AbstractA new type of Ni/Al2O3 self‐supporting catalysts, with high specific surface area, was fabricated by blow‐spinning technology. These Ni/Al2O3 self‐supporting catalysts are hollow flexible fibers and were utilized for the dry reforming of methane. The Ni/Al2O3 catalysts exhibited exceptional catalytic performance, maintaining their activity for over 150‐h at a high temperature of 800°C. The Ni nanoparticles disputed on the hollow fibers demonstrated remarkable resistance to sintering and coking during high‐temperature catalysis. This was a noteworthy feature, as sintering and coking are common challenges faced by catalysts during high‐temperature reactions. Furthermore, the catalysts retained its activity even after a rigorous 150‐h test at 800°C, indicating its durability and stability. Importantly, the Ni/Al2O3 self‐supporting could be successfully reactivated after the test, further highlighting its reusable nature. This study offers promising new avenues for the development of high‐temperature, self‐supporting, and reactivatable catalysts.
The recognition and the initial reaction to children's signals after experiencing maltreatment during childhood
Authors: Bérubé Annie , Turgeon Jessica , Tsur Noga , Talmon Anat 
Published: July 2024

AbstractMaltreatment during childhood has many long‐lasting effects. Victims often become parents who experience parenting difficulties, therefore contributing to the intergenerational cycle of maltreatment. This paper highlights the consequences of severe trauma during childhood on two processes critical for a sensitive response, namely the recognition of and the initial reaction to emotional signals. We argue that most interventions focus on the observed parental response to children's behaviors or on parental interpretation of children's signals, that is, the attribution of meaning or intent to the signal. Interventions should better integrate research indicating that a history of childhood maltreatment could impair the capacity to correctly identify the emotion and the immediate reaction to these signals. By failing to acknowledge these long‐lasting consequences of childhood maltreatment, scholars and practitioners might never achieve true success in intervening with families in the hope of breaking the intergenerational cycle of maltreatment.
Annexin A5 is a novel prognostic biomarker in oral squamous cell carcinoma
Authors: Zhou Ting , Zhang Xiaoxin , Song Yuxian , Ding Liang , Huang Xiaofeng , Zhang Lei , Ye Chuanjin , Yang Yan , Celentano Antonio , Hu Qingang , Ni Yanhong 
Published: July 2024

AbstractBackgroundANXA5, a notable tumor marker, displays irregular expression in diverse solid cancers, and links to local recurrence and metastasis rates. We aimed study the expression of ANXA5 in oral squamous cell carcinoma (OSCC) and its diagnostic and prognostic values.Methods520 head and neck squamous cell carcinoma (HNSCC) patients in TCGA database and 124 OSCC patients in Nanjing stomatology hospital were enrolled in our study. Immunohistochemical analyses were performed using ANXA5 antibodies. Chi‐square test was used to analyze the clinicopathological features. Survival rates were determined using the Kaplan–Meier method and log‐rank test.ResultsOur results showed significantly elevated ANXA5 at the gene and protein levels in HNSCC and OSCC compared to non‐tumor tissues. Histopathologically, ANXA5 was broadly present in OSCC tumor cells and fibroblast‐like cells but absent in tumor‐infiltrating lymphocytes, particularly at the invasive tumor front. Patients exhibiting high ANXA5 expression in these cells demonstrated poor differentiation, aggressive invasion patterns, and heightened lymph node metastasis risk, contributing to poorer postoperative outcomes. Remarkably, ANXA5 in fibroblast‐like cells emerged as an independent risk factor impacting survival in OSCC patients. Gene set enrichment analysis (GSEA) highlighted ANXA5's involvement in key pathways like epithelial‐mesenchymal transformation (EMT), TGF‐beta signaling, and hypoxia, which correlated with adverse clinical outcomes in OSCC.ConclusionANXA5 emerges as a significant prognostic biomarker for OSCC, potentially influencing its metastasis via the EMT pathway.
Understanding the role of temperature in seasonal timing: Effects on behavioural, physiological and molecular phenotypes
Authors: Sur Sayantan , Sharma Aakansha 
Published: July 2024

AbstractOrganisms adapt to daily and seasonal environmental changes to maximise their metabolic and reproductive fitness. For seasonally breeding animals, photoperiod is considered the most robust cue to drive these changes. It, however, does not explain the interannual variations in different seasonal phenotypes. Several studies have repeatedly shown the influence of ambient temperature on the timing of different seasonal physiologies including the timing of migration, reproduction and its associated behaviours, etc. In the present review, we have discussed the effects of changes in ambient temperature on different seasonal events in endotherms with a focus on migratory birds as they have evolved to draw benefits from distinct but largely predictable seasonal patterns of natural resources. We have further discussed the physiological and molecular mechanisms by which temperature affects seasonal timings. The primary brain area involved in detecting temperature changes is the hypothalamic preoptic area. This area receives thermal inputs via sensory neurons in the peripheral ganglia that measure changes in thermoregulatory tissues such as the skin and spinal cord. For the input signals, several thermal sensory TRP (transient receptor potential ion channels) channels have been identified across different classes of vertebrates. These channels are activated at specific thermal ranges. Once perceived, this information should activate an effector function. However, the link between temperature sensation and the effector pathways is not properly understood yet. Here, we have summarised the available information that may help us understand how temperature information is translated into seasonal timing.
Effects of ondansetron on symptoms during a gastric emptying study and enteral lipid challenge and on daily symptoms in diabetic gastroenteropathy
Authors: Varma Revati , Chakraborty Subhankar C. , Ramu Shivabalan Kathavarayan , Burton Duane D. , Deb Brototo , Ryks Michael D. , Feuerhak Kelly J. , Bailey Kent R. , Bharucha Adil E. 
Published: July 2024

AbstractBackgroundThis study compared the effects of ondansetron and placebo in patients with diabetes mellitus and symptoms of dyspepsia (diabetic gastroenteropathy [DGE]).MethodsWe performed a randomized, double‐blinded, placebo‐controlled study of ondansetron tablets (8 mg) three times daily for 4 weeks in DGE patients. Symptoms were assessed with the Gastroparesis Cardinal Symptom Index daily diaries. Gastric emptying (GE) of solids (scintigraphy) and duodenal lipid infusions (300 kcal over 2 h) were each assessed twice, with placebo and ondansetron. Drug effects on GE, symptoms during the GE study and during lipid infusion, and daily symptoms were analyzed.Key ResultsOf 41 patients, 37 completed both GE studies and one completed 1; 31 completed both lipid infusions and four only placebo; and all 35 randomized patients completed 4 weeks of treatment. Compared to placebo, ondansetron reduced the severity of fullness (p = 0.02) and belching (p = 0.049) during lipid infusion but did not affect GE T1/2. Both ondansetron and placebo improved daily symptoms versus the baseline period (p < 0.05), but the differences were not significant. In the analysis of covariance of daily symptoms during the treatment period, the interaction term between treatment and the acute effect of ondansetron on symptoms during lipid challenge was significant (p = .024).Conclusions & InferencesOndansetron significantly reduced fullness during enteral lipid infusion in patients with DGE. Overall, ondansetron did not improve daily symptoms versus placebo. But patients in whom ondansetron improved symptoms during enteral lipid challenge were perhaps more likely to experience symptom relief during daily treatment.
Personal and Social Worries Associated with the Likelihood of Having Children
Authors: Golovina Kateryna , Jokela Markus 
Published: July 2024

AbstractPrevious studies showed that worries about the economic situation and job security are associated with childbearing, but evidence is scarce on whether worries about other personal and social issues are also related to childbearing. Drawing on the German Socio‐Economic Panel Study, this study examined the relationship between worries about various personal and social issues and the likelihood of having children. Based on exploratory factor analysis, worries were categorized into social/environment and economy/safety factors. Cox regression models showed that social/environment worries were associated with a decreased likelihood of having children, even after adjusting for sociodemographic characteristics, personality traits, and political attitudes. Among specific worries, concerns about environmental protection, climate change, personal health, peace, immigration to Germany, and hostility toward immigrants were linked to a decreased likelihood of having children. Notably, worries about the economy in general were strongly associated with a reduced probability of becoming a parent among childless individuals, with a 25 percent lower likelihood for those highly worried about it. Similarly, childless individuals highly worried about climate change exhibit a 16 percent lower likelihood of parenthood. Our findings highlight the role of other worries in childbearing in addition to economic uncertainty and suggest that fertility decreases when the future is perceived as uncertain.
Intensity and associated factors of home health care service needs among elderly patients with chronic diseases in the community: A cross‐sectional survey
Authors: Li Hang , Liu Suzhen , Zhou Luling 
Published: July 2024

AbstractAim and ObjectivesThis study aimed to investigate the intensity of needs for home health care services (HHCs) among elderly patients with chronic diseases and to identify the associated factors.DesignA cross‐sectional survey was conducted in Wuhou District, Chengdu, Sichuan Province, China, from April to November 2021.MethodsConvenient sampling was used to screen elderly patients with chronic diseases managed by Yulin Community Health Service Center. The questionnaires included general information and the Chinese version of the Community Healthy Intensity Rating Scale were completed according to patients’ conditions. The data were analyzed using descriptive statistics and binary logistic regression.ResultsA total of 371 patients (10.40%) completed the survey. The mean age of the elderly patients was 84.04 years (SD = 7.07); these patients suffered from 1 to 7 kinds of chronic diseases, and the most common were hypertension (78.98%) and diabetes (40.97%). The need intensity of patients for HHCs was moderate (41.51%) or severe (58.49%). For each additional chronic disease that patients suffered from, the need intensity increases by 1.289 times (OR = 1.289; 95% CI: 1.055–1.575, p = .013); in additional, those aged more than 90 years, with a personal monthly income less than 2500 yuan ($387.00), with a poor health current status, and with only basic medical insurance presented greater need intensity (p < .05).ConclusionOur data analysis revealed that economic status, insurance condition, poor health status, and multiple comorbidities may be the most common factors associated with the need intensity for HHCs. These characteristics may help medical staff to identify and help those with urgent health problems.
Optimization of Ultrasonic-Assisted Extraction Condition for Total Phenolic Compounds from Citrus Hystrix Peel
Authors: Ong Chun Keat  , Wan Azelee Nur Izyan , Zainan Nur Hidayah 
Published: July 2024

This study aims to optimize the extraction conditions of Ultrasonic-Assisted Extraction (UAE) on the extraction of phenolic compound and antioxidant activity of Citrus Hystrix (C. Hystrix) peel. The experimental design was carried out using Face Centered Central Composite Design. A total of 20 sets of different combination experiment designs were generated from 3 parameters; temperature (30-50°C), time (20-40 min), and raw material to the solvent ratio (1:30-1:70). The highest yield of total phenolic compounds was 4.36 mg/g with the optimize extraction condition of , 30 min extraction time and 1:50 raw material to the solvent ratio. The result of this study indicates that the phenolic compounds extracted from C. Hystrix peel could have the potential to be used for pharmaceutical and food applications.
Screening of Different Fungi Strains Gongronella sp. WICC F60 and Cordyceps sp. WICC F61 for Degradation of Low-Density Polyethylene
Authors: Dailin Daniel Joe , Azzahra Sitty Zhaqia , Rithwan Fahim , Hanapi Siti Zulaiha , Rashidi Ahmad Ramli , Ramli Solleh , Abdul Manas Nor Hasmaliana , El Enshasy Hesham 
Published: July 2024

Over the past decade, polyethylene (PE) products have become increasingly important in several industries. Their biggest concerns are plastic material degradation resistance and environmental longevity. Therefore, this study aims to find fungi that are capable of degrading low-density polyethylene (LDPE) efficiently. This study uses Gongronella sp. WICC F60, and Cordyceps sp., WICC F61. The fungi were grown on potato dextrose agar for 30 days. Following that, fungal colonies were placed in potato dextrose broth for incubation. The LDPE sample was then cultured with the fungal strain in a minimum salt medium with a 10% inoculum. After 30 days of biodegradation testing, the analysis was done. These studies measured LDPE sample weight loss, pH, and fungal biomass. It was observed that the LDPE sample weight loss increased with time until the end of inclubation. Gongronella sp. WICC F60 and Cordyceps sp. WICC F61 were able to degrade LDPE plastic. Both fungi show an increase in LDPE weight loss. However, Cordyceps sp. WICC F61 shows more efficiency in LDPE degradation compared to Gongronella sp. WICC F60. The LDPE weight loss using Gongronella sp. WICC F60 was 1.07%, which is lower than Gongronella sp. WICC F60's LDPE weight reduction of 5.56%.
Orthonormal representations, vector chromatic number, and extension complexity
Authors: Balla Igor 
Published: July 2024

AbstractWe construct a bipartite generalization of Alon and Szegedy's nearly orthogonal vectors, thereby obtaining strong bounds for several extremal problems involving the Lovász theta function, vector chromatic number, minimum semidefinite rank, nonnegative rank, and extension complexity of polytopes. In particular, we answer a question from our previous work together with Letzter and Sudakov, while also addressing a question of Hrubeš and of Kwan, Sauermann, and Zhao. Along the way, we derive a couple of general lower bounds for the vector chromatic number which may be of independent interest.
Supporting breastfeeding for women with low education levels, psychosocial problems, and/or socioeconomic constraints: a scoping review protocol
Authors: Frandsen Annemi Lyng , Rytter Maren Johanne Heilskov , Beck Malene , Schiøtz Michaela Louise , Broberg Lotte 
Published: July 2024

Objective:
This scoping review aims to identify and map interventions and/or strategies used to support the initiation and continuation of breastfeeding for women at risk of delaying initiation, early cessation, or not breastfeeding due to low levels of education, psychosocial problems, and/or socioeconomic challenges in high-income countries.

Introduction:
While breastfeeding has lifelong beneficial health effects for women and infants, there is a risk of delaying initiation, early cessation, or not initiating breastfeeding at all due to factors related to health inequalities, such as low levels of education, psychosocial problems, and/or socioeconomic constraints.

Inclusion criteria:
This review will include eligible quantitative, qualitative, and mixed methods studies, as well as systematic reviews and gray literature. We will include studies conducted in high-income countries, focusing on interventions and/or strategies to support women with low levels of education, psychosocial problems, and/or socioeconomic constraints in the initiation and continuation of breastfeeding for up to 6 months postpartum.

Methods:
This review will follow the JBI methodology for scoping reviews, using the Participants, Concept, and Context framework. The primary search will be performed in MEDLINE (Ovid), PsycINFO (EBSCOhost), Embase (Ovid), and CINAHL (EBSCOhost). We will include publications in English, Swedish, Norwegian, Danish, German, Bulgarian, Arabic, and Spanish, published from 1991 until the present. A data charting form will be developed and used for all the included articles.

Review registration:
Open Science Framework https://osf.io/tmp4v/
Reliability Test of Mobile-Embedded Accelerometers and Gyroscopes With the Goal of Measuring Postural Stability for People With Parkinson's Disease
Authors: Thelen Matthew , Meeker Alexis , Mazumder Fardeen , Tabbah Mariam , Zhu Linda , Tang Charlotte , Miller Nathaniel S. 
Published: July 2024

Abstract
Parkinson's disease (PD) is the second most common neurodegenerative disease in the United States. The cardinal symptoms of PD are tremor, rigidity, slowed movement, and impaired balance. These symptoms often interfere with the daily activities of people with Parkinson's (PwPD) and negatively affect quality of life (QoL). Therefore, monitoring PD symptoms is essential for clinical evaluations and adjusting medication to help maintain QoL for PwPD. We are developing a mobile app to conduct at-home PD symptom monitoring to provide more timely, frequent, and accurate measurements of PD symptoms. While the tremor and finger-tapping results collected in the mobile app have been discussed in previous publications, this paper focuses on the design and evaluation of postural stability tests in the app and validating the reliability of the embedded accelerometers and gyroscopes in smartphones. During the test, a shaker was employed to provide vibration in amplitude and frequency ranges similar to human postural stability signals, and both the accelerometer and gyroscope measurements were evaluated. We used signal processing algorithms to extract postural stability factors, such as the root-mean-square (RMS) value, the derivative of acceleration, and frequency factors for the accelerations, and the ranges and RMS for the angular velocity. Our findings show that smartphone devices have good consistency over multiple trials and between devices, and motion patterns achieved from multiple data points are reliable for postural stability analysis.
Diagnosis and Management of Upper Gastrointestinal Bleeding in Long-Term NSAID Users : Case Report
Authors: Haitsam Muhamad Haitsam , Wardhani Shinta , Yudha Fakhmi 
Published: July 2024

Upper gastrointestinal bleeding is one of the most frequently encountered emergency cases. For most general practitioners, diagnosing and providing initial management is a challenge in itself. Upper gastrointestinal bleeding is divided into variceal and non-variceal bleeding. Clinical symptoms that can be found include hematemesis or melena. Patients with melena tend to have lower hemoglobin (Hb) levels than hematemesis because clinical manifestations appear more slowly. Drug Induced NSAIDs are also one of the etiologies that can cause upper gastrointestinal bleeding. Endoscopy is the gold standard for diagnosis, but not all health facilities are able to perform it.
This case reported a 66-years-old male patient came to the emergency room with complaints of blackish stools with a soft, sticky consistency for 6 days, accompanied by weakness, dizziness, nausea in the stomach and disruption of daily activities. The patient has a history of taking over-the-counter NSAIDs long term to relieve his knee pain. On physical examination, hepatomegaly and splenomegaly were not found and the patient’s hemodynamics is stable. On laboratory examination, Hb was found to be 3.4 g/dl. It was suspected that there was upper gastrointestinal bleeding, then received therapy in the form of PPI injections, antiemetic injections and planned PRC transfusion.
Track Deflection of Typhoon Chanthu (2021) near Taiwan as Investigated Using a High-Resolution Global Model
Authors: Chi Ya-Shin , Huang Ching-Yuang , Skamarock William C. 
Published: July 2024

Abstract
The Model for Prediction Across Scales (MPAS) with variable resolution (60–15–1 km) is used to investigate the track deflection of Typhoon Chanthu (2021) near Taiwan. Chanthu exhibited a rightward track deflection as it approached southeast Taiwan and underwent a leftward deflection when moving northward offshore of northeast Taiwan. Numerical experiments are conducted to identify the physical processes for the track deflection. The rightward deflection of the northbound typhoon is induced by the recirculating flow resulting from the effect of Taiwan’s topography. A wavenumber-1 potential vorticity (PV) budget analysis indicates that horizontal PV advection dominates the earlier rightward deflection, while the later leftward deflection is mainly in response to stronger asymmetric cloud heating at low levels at the offshore quadrant of the typhoon. A pair of cyclonic and anticyclonic gyres in the wavenumber-1 flow difference is induced by Taiwan’s topography. These rotate counterclockwise to drive the track deflection, most often in westbound typhoons. Idealized WRF simulations are also conducted to explore the track deflection under different northbound conditions. The simulations confirm the track deflection mechanism with similar PV dynamics to the MPAS simulations for Chanthu and illustrate the variabilities of the track deflection for different steering conditions and vortex origins. The rightward deflection of northbound typhoons is essentially determined by a reduced ratio of R/LE, where R is the vortex size and LE is the effective length of the mountain range.