bluuebunny/crossref_metadata_2025_split huggingface dataset:
Statistical Analysis of the Effect of the Temperature and Inlet Humidities on the Parameters of a PEMFC Model
Authors: Giner‐Sanz J. J. , Ortega E. M. , Pérez‐Herranz V. 
Published: April 2015

AbstractAn individual PEM fuel cell 6‐parameter mechanistic model was developed. In parallel, experimental polarization curves were obtained at different temperature and inlet gas humidities conditions. The 6 model parameters were determined by fitting the semi empirical model to the experimental curve using a non linear regression method. Finally, a statistical analysis was carried out in order to determine which operating conditions (temperature and inlet humidities) have a significant effect on which model parameters. A black box model was built in order to relate the model parameter values to the significant operating conditions for each one of them. The obtained model was able to satisfactory reproduce the experimental behaviour of the system at low current densities.
Underground CO2 storage: demonstrating regulatory conformance by convergence of history‐matched modeled and observed CO2 plume behavior using Sleipner time‐lapse seismics
Authors: Chadwick R. Andrew , Noy David J. 
Published: April 2015

AbstractOne of the three key regulatory requirements in Europe for transfer of storage site liability is to demonstrate conformity between predictive models of reservoir performance and monitoring observations. This is a challenging requirement because a perfect and unique match between observed and modeled behavior is near impossible to achieve. This study takes the time‐lapse seismic monitoring data from the Sleipner storage operation to demonstrate that as more seismic data becomes available with time, predictive models can be matched more accurately to observations and become more reliable predictors of future performance. Six simple performance measures were defined: plume footprint area, maximum lateral migration distance of CO2 from the injection point, area of CO2 accumulation trapped at top reservoir, volume of CO2 accumulation trapped at top reservoir, area of all CO2 layers summed, and spreading co‐efficient. Model scenarios were developed to predict plume migration up to 2008. Scenarios were developed for 1996 (baseline), 2001, and 2006 conditions, with models constrained by the information available at those times, and compared with monitoring datasets obtained up to 2008. The 1996 predictive range did generally encompass the future observed plume behavior, but with such a wide range of uncertainty as to render it of only marginal practical use. The 2001 predictions (which used the 1999 and 2001 seismic monitoring datasets) had a much lower uncertainty range, with the 2006 uncertainties somewhat lower again. There are still deficiencies in the actual quality of match but a robust convergence, with time, of predicted and observed models is clearly demonstrated. We propose modeling‐monitoring convergence as a generic approach to demonstrating conformance. © 2015 British Geological Survey. Greenhouse Gases: Science and Technology published by Society of Chemical Industry and John Wiley & Sons, Ltd.
Resection margins in oral cancer surgery: Room for improvement
Authors: Smits Roeland W.H. , Koljenović Senada , Hardillo Jose A. , ten Hove Ivo , Meeuwis Cees A. , Sewnaik Aniel , Dronkers Emilie A.C. , Bakker Schut Tom C. , Langeveld Ton P.M. , Molenaar Jan , Hegt V. Noordhoek , Puppels Gerwin J. , Baatenburg de Jong Robert J. 
Published: April 2015

AbstractThe purpose of this review was to identify publications on resection margins in oral cancer surgery and compare these with the results from 2 Dutch academic medical centers. Eight publications were considered relevant for this study, reporting 30% to 65% inadequate resection margins (ie, positive and close margins), compared to 85% in Dutch centers. However, clinical outcome in terms of overall survival and recurrence seemed comparable. The misleading difference is caused by lack of unanimous margin definition and differences in surgicopathological approaches. This prevents comparison between the centers. Data from Dutch centers showed that inadequate resection margins have a significantly negative effect on local recurrence, regional recurrence, distant metastasis, and overall survival. These results confirm the need for improvement in oral cancer surgery. We underline the need for consistent protocols and optimization of frozen section procedures. We comment on development of optical techniques for intraoperative assessment of resection margins. © 2015 Wiley Periodicals, Inc. Head Neck 38: E2197–E2203, 2016
Relationship between CO2 laser–induced artifact and glottic cancer surgical margins at variable power doses
Authors: Buchanan Malcolm A. , Coleman Hedley G. , Daley James , Digges James , Sandler Mark , Riffat Faruque , Palme Carsten E. 
Published: April 2015

AbstractBackgroundThe carbon dioxide laser can induce thermal cytologic artifacts at the margin of early glottic squamous cell carcinoma histologic specimens, which makes assessment of the margin difficult. This study assesses and correlates the depth of laser‐induced thermal artifact with laser power rating.MethodsThe surgical margins of 30 patients with early glottic squamous cell carcinomas who underwent laser resection were reanalyzed retrospectively.ResultsThermal damage consisted of collagen denaturation within the vocal cord lamina propria and vocalis muscle, and epithelial structural changes. There was a decrease in depth of tissue artifact with increased power rating (p > .05). The average depth of thermal damage was 380.83 ± 178.79 μm.ConclusionThe laser causes less thermal damage at higher power, presumably because of the increased speed of cutting and reduced contact time with surrounding cells. Knowledge of the depth of thermal artifact is important surgically when ensuring the cancer is excised with sufficient oncologic margin. © 2015 Wiley Periodicals, Inc. Head Neck 38: E712–E716, 2016
On the horizon: Optical imaging for cutaneous squamous cell carcinoma
Authors: de Boer Esther , Moore Lindsay S. , Warram Jason M. , Huang Conway C. , Brandwein–Gensler Margaret S. , van Dam Gooitzen M. , Rosenthal Eben L. , Schmalbach Cecelia E. 
Published: April 2015

AbstractBackgroundSurgical resection with negative margins remains the standard of care for high‐risk cutaneous squamous cell carcinoma (SCC). However, surgical management is often limited by poor intraoperative tumor visualization and inability to detect occult nodal metastasis. The inability to intraoperatively detect microscopic disease can lead to additional surgery, tumor recurrence, and decreased survival.MethodsA comprehensive literature review was conducted to identify studies incorporating optical imaging technology in the management of cutaneous SCC (January 1, 2000–December 1, 2014).ResultsSeveral innovative optical imaging techniques, Raman spectroscopy, confocal microscopy, and fluorescence imaging, have been developed for intraoperative surgical guidance. Fifty‐seven studies review the ability of these techniques to improve cutaneous SCC localization at the gross and microscopic level.ConclusionSignificant advances have been achieved with real‐time optical imaging strategies for intraoperative cutaneous SCC margin assessment and tumor detection. Optical imaging holds promise in improving the percentage of negative surgical margins and in the early detection of micrometastatic disease. © 2015 Wiley Periodicals, Inc. Head Neck 38: E2204–E2213, 2016
Effect of Hashimoto thyroiditis on low‐dose radioactive‐iodine remnant ablation
Authors: Kwon Hyungju , Choi June Young , Moon Jae Hoon , Park Hyo Jin , Lee Won Woo , Lee Kyu Eun 
Published: April 2015

AbstractBackgroundRadioactive‐iodine remnant ablation is an integral part of the papillary thyroid carcinoma (PTC) treatment. Although a minimum dose is usually recommended, there is controversy as to whether the low‐dose (1100 MBq) radioactive‐iodine remnant ablation is adequate for selected patients.MethodsA retrospective cohort study was conducted on 691 patients. Patients with no remnant thyroid on the follow‐up whole body scan and low stimulated thyroglobulin (sTg) level (<2.0 ng/mL) were deemed as successful treatment cases.ResultsInitial low‐dose radioactive‐iodine remnant ablation was successful in 431 patients (62.3%). Multivariate analysis demonstrated a negative correlation between successful radioactive‐iodine remnant ablation and coexisting Hashimoto thyroiditis based on histopathology diagnosis (odds ratio [OR] = 3.23; p < .001) as well as elevated preablation sTg (OR = 1.24; p < .001).ConclusionOur data suggest that coexisting Hashimoto thyroiditis and elevated sTg are negative predictive factors for successful low‐dose radioactive‐iodine remnant ablation treatment. An appropriate risk‐adjusted approach may improve the efficacy of radioactive‐iodine remnant ablation treatment. © 2015 Wiley Periodicals, Inc. Head Neck 38: E730–E735, 2016
Sialoblastoma of the parotid gland in a 13‐year‐old girl with multiple recurrences and long‐term follow‐up
Authors: Saravakos Panagiotis , Hartwein Joerg , Fayyazi Afshin 
Published: April 2015

AbstractBackgroundSialoblastoma is an extremely rare congenital salivary gland tumor of epithelial origin. It is usually localized in the parotid or submandibular gland and presents primarily at birth or in early childhood.MethodsWe report a case of a 13‐year‐old girl with a sialoblastoma of the parotid gland presenting as an asymptomatic painless mass.ResultsThe patient showed multiple recurrences and, based on the histopathological finding of facial nerve infiltration, was treated surgically with total parotidectomy and facial nerve reconstruction.ConclusionBecause of the rare occurrence of sialoblastoma, there is no evidence‐based treatment of choice. The treatment should be individualized, taking into consideration the patient's age, the high locoregional recurrence rate, the local aggressive characteristics, and the potential metastatic activity of this rare tumor. A close follow‐up of the patient is strongly recommended. © 2015 Wiley Periodicals, Inc. Head Neck 38: E13–E15, 2016
Nodular fasciitis of the tongue
Authors: Celentano Antonio , Mascolo Massimo , De Rosa Gaetano , Mignogna Michele Davide 
Published: April 2015

AbstractBackgroundNodular fasciitis is a non‐neoplastic proliferation within the subcutaneous tissue and the deep fascia of the fibroblasts, probably of a reactive nature characterized by apparent infiltration of the connective tissues by a mitotically active spindle cell lesion. Nodular fasciitis in the head/neck region is rarely found and only 2 previous cases affecting the tongue have been reported.Methods and ResultsThe purpose of this study was for us to report a very rare case of a 67‐year‐old man with a history of a 3‐month subepithelial asymptomatic nodule of the tongue tip with an ulcerated surface. An excisional biopsy of the mass was performed with 0.5‐mm surgical margins.ConclusionThe clinical and histological features of nodular fasciitis may mimic a head and neck malignancy, but it is often misdiagnosed as a malignant mesenchymal neoplasm. Even if it is a rare entity, nodular fasciitis should be considered in cases of rapidly growing masses of the head and neck region. © 2015 Wiley Periodicals, Inc. Head Neck 38: E29–E31, 2016
Perfect Graphs with No Balanced Skew‐Partition are 2‐Clique‐Colorable
Authors: Penev Irena 
Published: April 2015

AbstractA graph G is perfect if for all induced subgraphs H of G, . A graph G is Berge if neither G nor its complement contains an induced odd cycle of length at least five. The Strong Perfect Graph Theorem [9] states that a graph is perfect if and only if it is Berge. The Strong Perfect Graph Theorem was obtained as a consequence of a decomposition theorem for Berge graphs [M. Chudnovsky, Berge trigraphs and their applications, PhD thesis, Princeton University, 2003; M. Chudnovsky, N. Robertson, P. Seymour, and R. Thomas, The strong perfect graph theorem, Ann Math 164 (2006), 51–229.], and one of the decompositions in this decomposition theorem was the “balanced skew‐partition.” A clique‐coloring of a graph G is an assignment of colors to the vertices of G in such a way that no inclusion‐wise maximal clique of G of size at least two is monochromatic, and the clique‐chromatic number of G, denoted by , is the smallest number of colors needed to clique‐color G. There exist graphs of arbitrarily large clique‐chromatic number, but it is not known whether the clique‐chromatic number of perfect graphs is bounded. In this article, we prove that every perfect graph that does not admit a balanced skew‐partition is 2‐clique colorable. The main tool used in the proof is a decomposition theorem for “tame Berge trigraphs” due to Chudnovsky et al. (http://arxiv.org/abs/1308.6444).
Control of citrus molds using bioactive coatings incorporated with fungal chitosan/plant extracts composite
Authors: Tayel Ahmed A , Moussa Shaaban H , Salem Mohammed F , Mazrou Khaled E , El‐Tras Wael F 
Published: April 2015

AbstractBACKGROUNDThe ongoing postharvest loss in citrus fruits, due to fungal infection, is a chronic economic and agricultural problem. Most of citrus damage is caused by Penicillium spp., e.g. green mold (P. digitatum) and blue mold (P. italicum). Fungal chitosan, from Mucor rouxii, and plant extracts from cress seeds, olive leaves, pomegranate peels and senna pods, were evaluated as antifungal agents against the phytopathogenic fungi, P. digitatum and P. italicum, using in vitro qualitative and quantitative assays.RESULTSAll natural agents tested exhibited potent antifungal activity; the most powerful agent was cress (Lepidium sativum) seed extract, followed by pomegranate (Punica granatum) peel extract. Fungal chitosan also had a remarkable fungicidal potentiality using both evaluation assays. Penicillium digitatum was generally more resistant than P. italicum toward all examined agents. The incorporation of each individual natural agent in coating material resulted in a great reduction in fungal growth and viability. The addition of chitosan combined with cress and pomegranate extracts, to the coating materials, prevented coated citrus fruit from decay by green and blue mold for a 2‐week storage period.CONCLUSIONNatural derivatives could be recommended as powerful antifungal alternatives to protect citrus fruits from postharvest fungal decay. © 2015 Society of Chemical Industry
Sensory and nutritional attributes of pomegranate juices extracted from separated arils and pressed whole fruits
Authors: Mayuoni Kirshenbaum Lina , Benjamin Ofir , Porat Ron 
Published: April 2015

AbstractBACKGROUNDThe present study aimed to compare the sensory and nutritional attributes of ‘Wonderful’ pomegranate juices extracted from separated arils with those from pressed whole fruits.RESULTSFive different sensory tests were conducted to evaluate the flavor quality of ‘Wonderful’ pomegranate juices. Consumer acceptance tests revealed that juice from separated arils achieved significantly higher likability scores than that from whole pressed fruits. Furthermore, preference tests revealed that 84% of the tasters preferred the juice extracted from separated arils whereas only 16% preferred the juice from whole pressed fruits. Sensory discrimination tests (triangle tests) revealed that tasters significantly distinguished between the two juices at P ≤ 0.01. Descriptive tests by a trained panel and sensory analysis with an electronic tongue demonstrated that juice from whole pressed fruits was more astringent and had a stronger aftertaste than juice from separated arils. Juice from pressed whole fruits contained significantly higher levels of phenols and hydrolysable tannins, which led to higher astringency.CONCLUSIONSPomegranate juice extracted from separated arils was less astringent and more preferred by tasters than juice from whole pressed fruits. Nonetheless, juice from separated arils has lower nutritional benefits. © 2015 Society of Chemical Industry
Tree age, fruit size and storage conditions affect levels of ascorbic acid, total phenolic concentrations and total antioxidant activity of ‘Kinnow’ mandarin juice
Authors: Khalid Samina , Malik Aman U , Khan Ahmad S , Shahid Muhammad , Shafique Muhammad 
Published: April 2015

AbstractBACKGROUNDBioactive compounds (ascorbic acid, total phenolics and total antioxidants) are important constituents of citrus fruit juice; however, information with regard to their concentrations and changes in relation to tree age and storage conditions is limited. ‘Kinnow’ (Citrus nobilis Lour × Citrus deliciosa Tenora) mandarin juice from fruit of three tree ages (6, 18 and 35 years old) and fruit sizes (large, medium and small) were examined for their bioactive compounds during 7 days under ambient storage conditions (20 ± 2 °C and 60–65% relative humidity (RH)) and during 60 days under cold storage (4 ± 1 °C and 75–80% RH) conditions.RESULTSUnder ambient conditions, a reduction in total phenolic concentrations (TPC) and in total antioxidant activity (TAA) was found for the juice from all tree ages and fruit sizes. Overall, fruit from 18‐year‐old trees had higher mean TPC (95.86 µg mL−1) and TAA (93.68 mg L−1), as compared to 6 and 35‐year‐old trees. Likewise, in cold storage, TAA decreased in all fruit size groups from 18 and 35‐year‐old trees. In all tree age and fruit size groups, TPC decreased initially during 15 days of cold storage and then increased gradually with increase in storage duration. Ascorbic acid concentrations showed an increasing trend in all fruit size groups from 35‐year‐old trees. Overall, during cold storage, fruit from 18‐year‐old trees maintained higher mean ascorbic acid (33.05 mg 100 mL−1) concentrations, whereas fruit from 6‐year‐old trees had higher TAA (153.1 mg L−1) and TPC (115.1 µg mL−1). Large‐sized fruit had higher ascorbic acid (32.08 mg 100 mL−1) concentrations and TAA (157.5 mg L−1).CONCLUSIONFruit from 18‐year‐old trees maintained higher TPC and TAA under ambient storage conditions, whereas fruit from 6‐year‐old trees maintained higher TPC and TAA during cold storage. Small‐sized fruit had higher TPC after ambient temperature storage, whereas large fruit size showed higher ascorbic acid concentrations and TAA after cold storage. © 2015 Society of Chemical Industry
Unimolecular Rate Constants for the HF and HCl Elimination Reactions from Chemically Activated CF2ClSH
Authors: Rossabi Samuel M. , Smith Kylie C. , Heard George L. , Holmes Bert E. 
Published: April 2015

ABSTRACTChemically activated CF3SH, CFCl2SH, and CF2ClSH were formed through combination of SH and CF3, CFCl2, and CF2Cl radicals, respectively. The SH radical was prepared by abstraction of an H‐atom from H2S by the halocarbon radical produced during photolysis of (CF3)2C=O, (CFCl2)2C=O, or (CF2Cl)2C=O. 1,2‐HX (X = F, Cl) elimination reactions were observed from CF3SH, CFCl2SH, and CF2ClSH with products detected by GC‐MS. The combination reaction of CF2Cl radicals with SH radicals prepared CF2ClSH molecules with approximately 318 kJ/mol of internal energy. The experimental rate constants for elimination of HCl and HF from CF2ClSH were 3 ± 3 × 1010 and 2 ± 1 × 109 s−1, respectively. Comparison to Rice–Ramsperger–Kassel–Marcus (RRKM) calculated rate constants assigned the threshold energies as 171 ± 12 and 205 ± 12 kJ/mol for the unimolecular elimination of HCl and HF, respectively. Theoretical calculations using the B3PW91, MP2, and M062X methods with the 6311+G(2d,p) and 6‐31G(d',p') basis sets established that for a specific method the threshold energies differ by only 4 kJ/mol between the two different basis sets. There was wide variation among the three methods, but the M062X approach appeared to give threshold energies closest to the experimental values. Chemically activated CF3SH and CFCl2SH were also prepared with about 318 kcal mol−1 of internal energy, and the HX (X = F, Cl) elimination reactions were observed. Only HCl loss was detected from CFCl2SH, but the rate was too fast to measure with our kinetic method; however, based on our detection limit the HF elimination channel is at least 50 times slower.
Competition between photochemical and biological degradation of dissolved organic matter from the cyanobacteria Microcystis aeruginosa
Authors: Bittar Thais B. , Vieira Armando A. H. , Stubbins Aron , Mopper Kenneth 
Published: April 2015

AbstractExtracellular and intracellular dissolved organic matter (E‐DOM and I‐DOM, respectively) produced in axenic cultures by the cosmopolitan cyanobacteria Microcystis aeruginosa were characterized, and photoreactivity, bioreactivity, and the effects of phototransformations on bioavailability of E‐DOM and I‐DOM were assessed in laboratory experiments. Chromophoric (CDOM) and fluorescent (FDOM) properties were analyzed by spectrophotometry, and chemical signatures were obtained by ultrahigh resolution Fourier transform ion cyclotron resonance mass spectrometry (FTICR‐MS). E‐DOM was more heterogeneous regarding optical characteristics as indicated by the presence of multiple CDOM peaks and the more even distribution of FDOM components, and had less absolute and relative numbers for molecular formulae containing nitrogen (N) than I‐DOM. E‐DOM was more photolabile, with greater photochemical removal of dissolved organic carbon (DOC), CDOM and FDOM, and exhibited more pronounced photochemical alterations in molecular formulae composition than I‐DOM. E‐DOM was less biolabile, with less biological removal of DOC, CDOM, and protein‐like fluorescent material, and supported lower rates of bacterial productivity than I‐DOM. Phototransformations reduced the bioavailability of E‐DOM and I‐DOM, as shown by lower bacterial productivity and longer DOC and CDOM half‐lives in bioassays with photoirradiated DOM in comparison to those with nonirradiated DOM. Analyses of CDOM, FDOM, and FTICR‐MS revealed that the decrease in bioavailability was caused primarily by photolysis of the biolabile DOM, indicating competition between photochemical and biological removal of cyanobacterial DOM. These results provided insights into mechanistic effects of independent and combined photochemical and biological degradation on M. aeruginosa‐derived DOM.