bluuebunny/crossref_metadata_2025_split huggingface dataset:
Chronic alcohol produces neuroadaptations to prime dorsal striatal learning
Authors: DePoy Lauren , Daut Rachel , Brigman Jonathan L. , MacPherson Kathryn , Crowley Nicole , Gunduz-Cinar Ozge , Pickens Charles L. , Cinar Resat , Saksida Lisa M. , Kunos George , Lovinger David M. , Bussey Timothy J. , Camp Marguerite C. , Holmes Andrew 
Published: August 2013

Significance
Alcoholism is characterized by a progressive degradation of executive control and an increase in compulsive alcohol seeking that is hypothesized to involve a shift from prefrontal cortex to dorsal striatal (DLS) control over behavior. Here, we show that mice exposed to chronic intermittent alcohol exhibited expansion of dendritic material in DLS neurons, coupled with loss of endocannabinoid CB1 receptor signaling and CB1-mediated long-term depression in the DLS. Behaviorally, chronic alcohol exposure facilitated various forms of DLS-dependent learning and augmented in vivo DLS neuronal activity as correct learned choices were made. These findings support a model in which chronic ethanol causes DLS neuroadaptations that prime for greater striatal control over behavior, potentially contributing to the progression of alcoholism.
Insights into Eph receptor tyrosine kinase activation from crystal structures of the EphA4 ectodomain and its complex with ephrin-A5
Authors: Xu Kai , Tzvetkova-Robev Dorothea , Xu Yan , Goldgur Yehuda , Chan Yee-Peng , Himanen Juha P. , Nikolov Dimitar B. 
Published: August 2013

Significance
Our paper describes the high-resolution structures of the complete EphA4 receptor tyrosine kinase ectodomain and its complex with ephrin-A5. These structures reveal for the first time how ephrin binding promotes Eph conformational changes allowing for the formation of ordered signaling clusters at the sites of cell–cell contact. In addition, the structural data, combined with structure-based mutagenesis and cell-based assays, reveal a previously undescribed receptor–receptor interaction between the EphA4 ligand-binding and membrane-proximal fibronectin domains, which is functionally important for efficient Eph activation. Based on the data we suggest a mechanism for Eph preclustering and recruitment of unliganded Eph into existing Eph/ephrin signaling clusters.
Reproductive Biology of the Cuban Dogfish in the Northern Gulf of Mexico
Authors: Jones Lisa M. , Driggers William B. , Hoffmayer Eric R. , Hannan Kristin M. , Mathers Alyssa N. 
Published: August 2013

Abstract
Within the northern Gulf of Mexico, the Cuban Dogfish Squalus cubensis is the most frequently encountered squalid in continental shelf and slope waters. Despite the relatively high abundance of Cuban Dogfish in the region, there is a dearth of information regarding even the most basic aspects of the species’ biology. Furthermore, what has been reported is conflicting and of questionable utility. From 2005 to 2012, 139 male and 252 female Cuban Dogfish were collected opportunistically. The analyses indicated that male Cuban Dogfish reach 50% maturity at 379 mm stretch total length (STL) and are capable of reproducing throughout the year. Females reach 50% maturity at 466 mm STL and 50% maternity at 478 mm STL. Brood size ranges from one to four, and vitellogenesis and gestation are concurrent. Although samples were not collected during all months of the year, the presence of ova in the blastodisc stage of development during the summer and fall, coupled with the relatively high variability of embryo size within fall months, suggest that Cuban Dogfish reproduce asynchronously.
Received October 29, 2012; accepted January 9, 2013
HippDB: a database of readily targeted helical protein–protein interactions
Authors: Bergey Christina M. , Watkins Andrew M. , Arora Paramjit S. 
Published: August 2013

Abstract
Summary: HippDB catalogs every protein–protein interaction whose structure is available in the Protein Data Bank and which exhibits one or more helices at the interface. The Web site accepts queries on variables such as helix length and sequence, and it provides computational alanine scanning and change in solvent-accessible surface area values for every interfacial residue. HippDB is intended to serve as a starting point for structure-based small molecule and peptidomimetic drug development.
Availability and implementation: HippDB is freely available on the web at http://www.nyu.edu/projects/arora/hippdb. The Web site is implemented in PHP, MySQL and Apache. Source code freely available for download at http://code.google.com/p/helidb, implemented in Perl and supported on Linux.
Contact: arora@nyu.edu
A fast Peptide Match service for UniProt Knowledgebase
Authors: Chen Chuming , Li Zhiwen , Huang Hongzhan , Suzek Baris E. , Wu Cathy H. ,   UniProt Consortium
Published: August 2013

Abstract
Summary: We have developed a new web application for peptide matching using Apache Lucene-based search engine. The Peptide Match service is designed to quickly retrieve all occurrences of a given query peptide from UniProt Knowledgebase (UniProtKB) with isoforms. The matched proteins are shown in summary tables with rich annotations, including matched sequence region(s) and links to corresponding proteins in a number of proteomic/peptide spectral databases. The results are grouped by taxonomy and can be browsed by organism, taxonomic group or taxonomy tree. The service supports queries where isobaric leucine and isoleucine are treated equivalent, and an option for searching UniRef100 representative sequences, as well as dynamic queries to major proteomic databases. In addition to the web interface, we also provide RESTful web services. The underlying data are updated every 4 weeks in accordance with the UniProt releases.
Availability: http://proteininformationresource.org/peptide.shtml
Contact: chenc@udel.edu
Supplementary information: Supplementary data are available at Bioinformatics online.
Influence of Bran Particle Size on Bread‐Baking Quality of Whole Grain Wheat Flour and Starch Retrogradation
Authors: Cai Liming , Choi Induck , Hyun Jong‐Nae , Jeong Young‐Keun , Baik Byung‐Kee 
Published: August 2013

ABSTRACTThe influence of bran particle size on bread‐baking quality of whole grain wheat flour (WWF) and starch retrogradation was studied. Higher water absorption of dough prepared from WWF with added gluten to attain 18% protein was observed for WWFs of fine bran than those of coarse bran, whereas no significant difference in dough mixing time was detected for WWFs of varying bran particle size. The effects of bran particle size on loaf volume of WWF bread and crumb firmness during storage were more evident in hard white wheat than in hard red wheat. A greater degree of starch retrogradation in bread crumb stored for seven days at 4°C was observed in WWFs of fine bran than those of coarse bran. The gels prepared from starch–fine bran blends were harder than those prepared from starch–unground bran blends when stored for one and seven days at 4°C. Furthermore, a greater degree of starch retrogradation was observed in gelatinized starch containing fine bran than that containing unground bran after storage for seven days at 4°C. It is probable that finely ground bran takes away more water from gelatinized starch than coarsely ground bran, increasing the extent of starch retrogradation in bread and gels during storage.
Human capital disclosures in developing countries: figureheads and value creators
Authors: Choo Huang Ching , Luther Robert , Tayles Michael , Haniffa Roszaini 
Published: August 2013

Purpose– The purpose of this paper is to explore if any disparity exists between human capital information desired by financial analysts and fund managers and actual disclosure of such information in company annual reports, in the context of developing countries.Design/methodology/approach– Financial analysts and fund managers were interviewed to obtain opinions on the importance attributed to human capital information and whether their desired information is disclosed in the annual reports. Content analysis was then used to assess the extent and nature of human capital information actually provided in the annual reports of 100 listed companies in Malaysia.Findings– Interviewees seek information on company management and key corporate decision makers who could provide a firm with competitive advantage. However, the human capital information provided is limited, and tends to focus on directors, many of whom may be figureheads with little impact on the way companies are run and in creating value for the firm. Accordingly, analysts rely on alternative sources to get their desired information – a costly process for private shareholders.Originality/value– The paper contributes to the literature on the demand for, and disclosure of, human capital information in the context of developing countries. It identifies the inadequacy of current human capital disclosure practices in company annual reports. The authors theorise that in developing countries, resource dependence, legitimacy-seeking and “culture” cause companies to pay relatively more attention to figureheads than value creators.
Corrosion behaviour of Mn‐Si‐Fe‐Cu‐Al alloy explosion suppression materials
Authors: Jing Yan , Zhang Chao , Ma Jun , Jia Yongzhong 
Published: August 2013

PurposeThe purpose of this paper is to prepare the Mn‐Si‐Fe‐Cu‐Al alloy explosion suppression materials, and determine the corrosion behavior of aluminum alloy explosion suppression materials in HCl and NaOH solutions. The different mechanism of corrosion was discussed.Design/methodology/approachIn this paper, Mn‐Si‐Fe‐Cu‐Al alloy explosion suppression materials were prepared, and the electrochemical behavior of the EAESM was studied. The corrosion parameters were calculated and the mechanism of the corrosion process was discussed. The corrosion behavior was characterized by immersion tests and SEM at room temperature.FindingsMn‐Si‐Fe‐Cu‐Al alloy explosion suppression materials have been prepared. SEM, the polarization curves showed that materials have corrosion resistance. The best content of Al alloy is Mn 0.880%, Si 0.135%, Fe 0.383% and Cu 0.0835%.Originality/valueThe results of this investigation show that adding alloying elements can form new strengthening phases that influence the corrosion resistance of alloys.
Research into sulfide resistant polymer latex cement for sour well applications
Authors: Ren Chengqiang , He Yi , Zeng Dezhi , Shi Taihe 
Published: August 2013

PurposeThe long‐term durability of cement becomes an important challenge in oil and gas wells due to the aggressive acid gas. H2S has been found in more and more wells. The purpose of this research was to add polymer latex to the Class G cement in order to promote the H2S corrosion resistance of oilwell cement.Design/methodology/approachThe water loss and thickening time of cement slurry and compressive strength and gas permeability of bond cement were investigated to determine the cement formulation. The corrosion resistance of the polymer cement was compared to base Class G cement in solution with 1.8 MPa H2S at 120°C.FindingsThe optimum concentration of polystyrene latex was determined as 5 percent. The permeability change, compressive strength loss and corrosion ratio of latex cement were all lower than for the base Class G cement. The electrochemical impedance spectroscopy results and microstructure details confirmed that the latex cement had stronger resistance to the aggressive medium. Thus, latex cement had excellent corrosion resistance to H2S.Originality/valueThe findings of this study can further improve the sulfide resistance of Class G cement. Two roles of the polystyrene latex were observed in the cement, including interstitial in‐filling of the pore structure and packing around hydration products, which are proposed to properly explain the results.
Optimization of the aircraft general overhaul process
Authors: Rašuo Boško , Đuknić Gradimir 
Published: August 2013

PurposeThe purpose of this paper is to present the development results of the overhaul melioration plan for the following aircraft types: MiG‐21Bis, G‐4 Galeb and SA‐341 helicopter. This research has been conducted based on available knowledge and extensive experience gained by performing general maintenance of the Air Force of Serbia aircraft.Design/methodology/approachA general analysis was performed by processing data collected while performing maintenance and repair procedures. The magnitude of data is based on detecting the delays and errors that occurred while going through the operational and inter‐operational stages of aircraft overhaul. On the basis of the obtained research results, a proposal for the aircraft overhaul optimization is offered.FindingsThe proposed overhaul improvement plan points out the priority steps to be taken in order to optimize the most critical features that jeopardize the quality of the aircraft overhaul process relating to organization, technology and design. Moreover, existing technical logistics have been used for providing actions to achieve the objective in focus: the all‐encompassing optimization of the above selected aircraft overhaul.Research limitations/implicationsThe method of the overhaul optimization has so far been applicable to the aircraft of the Army of Serbia. However, the particular methodology can be proved potentially useful and highly germane when applying to other aircraft types.Originality/valueA plan to optimize the overhaul is based on a one‐year monitoring process of the aforementioned aircraft. It enables significant savings in performing overhauls within the financial realm as well as time‐wise.
Reusable boosted vehicle attitude controller design
Authors: Xu Jiangtao , Qi Hui , Chen Weidong , Wu Xiande 
Published: August 2013

PurposeThe purpose of this paper is to develop an attitude control strategy for the reusable boosted vehicle with large angle of attack, and to remove the cross coupling among roll, pitch and yaw channels.Design/methodology/approachThe coordinated gain scheduling control strategy consists mainly of two parts. First, initially ignoring dynamic coupling, single channel gain scheduling controller is designed based on linearized models, respectively. Second, with respect to main channel gain scheduling controller, coordinated scheduling controller is used to generate intentionally cross coupling to partly cancel inter‐channel cross coupling of reusable boosted vehicle.FindingsA coordinated gain scheduling control strategy is presented, and no such analytical solution can be found for the reusable boosted vehicle.Practical implicationsThe design idea of coordinated gain scheduling strategy is straightforward in physical concepts and has great value for engineering applications.Originality/valueCoordinated gain scheduling control strategy is novel in that single channel gain scheduling design does not involve small perturbation linearization and coordinated channel is scheduled.
Optimization of flatback airfoils for wind turbine blades
Authors: Chen Xiaomin , Agarwal Ramesh 
Published: August 2013

PurposeIn recent years, the airfoil sections with blunt trailing edge (called flatback airfoils) have been proposed for the inboard regions of large wind‐turbine blades because they provide several structural and aerodynamic performance advantages. The purpose of this paper is to optimize the shape of these airfoils for optimal performance using a multi‐objective genetic algorithm.Design/methodology/approachA multi‐objective genetic algorithm is employed for shape optimization of flatback airfoils to achieve two objectives, namely the generation of maximum lift as well as the maximum lift to drag ratio. The commercially available software FLUENT is employed for calculation of the flow field using the Reynolds‐Averaged Navier‐Stokes (RANS) equations in conjunction with a two‐equation Shear Stress Transport (SST) turbulence model and a three‐equation k‐kl‐ω turbulence model.FindingsIt is shown that the multi‐objective genetic algorithm based optimization can generate superior flatback airfoils compared to those obtained by using a single objective genetic algorithm.Research limitations/implicationsThe method of employing genetic algorithms for shape optimization of flatback airfoils could be considered as an excellent example for the optimization of other types of wind turbine blades such as DU FX and S series airfoils.Originality/valueThis paper is the first to employ the multi‐objective genetic algorithm for shape optimization of flatback airfoils for wind‐turbine blades to achieve superior performance.
Turbofan multiobjective‐multipoint optimization for UAV/UCAV applications
Authors: Benini Ernesto , Chiereghin Nicola 
Published: August 2013

PurposeThe purpose of this paper is to present a multi‐objective and multi‐point optimization method to support the preliminary design of an unmixed turbofan mounted on a sample UAV/UCAV aircraft.Design/methodology/approachAn in‐house multi‐objective evolutionary algorithm, a flight simulator and a validated engine simulator are implemented and joined together using object‐oriented programming.FindingsOptimal values are found of the pressure ratio and corrected mass flow of both the engine fan and compressor as they operate in on/off design conditions (multipoint approach), as well as the engine by‐pass ratio, that contextually minimize time and engine fuel consumption required to cover a fixed trajectory (mission profile). Furthermore, the optimal distribution of the thermodynamic quantities along the trajectory is determined.Research limitations/implicationsThe research deals with a preliminary design of an engine, therefore no detailed engine geometry can be found.Practical implicationsThe paper shows how a multiobjective and multipoint approach to the design of an engine can affect the choice of the engine architecture. In particular, major practical implications regard how the mission profile can affect the choice of the design point: in fact, there is no longer a definitive design point but the design of a UAV/UCAV should be addressed as a function of the mission profile.Originality/valueThe paper presents a multiobjective and multipoint approach to engine optimization as a function of the mission profile.
Unlocking the laboratory: autonomous wireless sensor authentication in practice
Authors: Huggard Meriel , Mc Goldrick Ciarán 
Published: August 2013

PurposeThe purpose of this study is to evaluate a practical laboratory task where final year undergraduate students design, implement and validate an inferred security wireless sensor access system.Design/methodology/approachThe quality of the learning and technical environment was evaluated from a number of perspectives using a mixed methods approach where both quantitative and qualitative data was collected and analysed. Two‐tailed paired t‐tests were used to analyse data on student performance, while a targeted survey was used to assess the achievement of the learning outcomes. The students’ experience of working with the Sun Microsystems SunSPOTs was evaluated and the evolution of their perception of both ubiquity and security from inception to completion of the activity was explored.FindingsThe results of this study indicate that the students’ level of engagement with the assigned laboratory task was higher than with the two other forms of continuous assessment used on the module. Quantitative feedback gathered indicated that the learning outcomes were achieved, while the qualitative data indicated a high level of student satisfaction with the laboratory assignment.Originality/valueA novel wireless sensor network laboratory that encourages students to engage with the concepts of ubiquity and security is presented and evaluated.
On computational algorithms of grey numbers based on information background
Authors: Xie Nai‐ming 
Published: August 2013

PurposeThe purpose of this paper is to redefine the concept of grey number with information background and to propose novel grey number algorithms.Design/methodology/approachAs the basic element of a grey system, grey number is defined as a number of which the true value is unknown because of the limited information while the boundary or possible value set can be known. Grey number algorithms are key points for constructing grey system models and helping to calculate model results. The concept of grey number is redefined with information background in this paper. Novel grey number algorithms are defined considering all the different forms of grey number information background. Several illustrative examples are applied to state the process of the proposed algorithms.FindingsThe results show that the novel grey number algorithms can do the operations well no matter what the grey number's type. It is useful to create effective grey system models and to do system analysis, forecasting, decision making and control in grey systems.Practical implicationsThe method exposed in the paper can be used to calculate different grey numbers and used in constructing new grey models.Originality/valueThe paper succeeds in defining new grey number algorithm. The concept and its remarks of grey number are discussed. The novel algorithm can be used in creating new grey models and solve the modelling parameters in of grey systems theory undoubtedly.
Work‐life balance in times of economic crisis and austerity
Authors: Gregory Abigail , Milner Susan , Windebank Jan 
Published: August 2013

PurposeThe purpose of this editorial is to provide an overview of the wider debates concerning the evolution of work‐life balance practice and policy since the onset of the “Great Recession” of 2008 and to draw out some comparisons of the issues raised by the papers in the special issue by focusing particularly on the example of the UK.Design/methodology/approachThe editorial analyses how the direction and pace of changes in work‐life balance practice and policy varies between different national contexts and welfare regimes and also asks whether, within the same national context, the changes taking place are always consistent.FindingsThe special issue draws together an international overview of work‐life balance measures which focuses particularly on measures for fathers, an EU‐wide analysis of the use of flexible employment and its relationship with work‐family conflict and a number of specific country case studies from Southern Europe where recession has been particularly severe (Spain and Italy) and the Southern hemisphere (Australia) where the recession has been less deep. It finds that economic crisis and austerity have resulted in a variety of labour market changes and policy responses in different national settings, some but not all of which map onto existing welfare regime typologies. The articles raise a wider set of questions about what type of policy best promotes employees' work‐life balance. The editorial argues in favour of legislative support for work‐life balance to help address structural inequalities.Originality/valueThis editorial and special issue is one of the first to review the small but growing literature on the effect of recession on individuals' experience of work‐life balance, organisations' approach to work‐life balance and reconciliation policy since 2008.