bluuebunny/crossref_metadata_2025_split huggingface dataset:
Design calculations of an extractor for aromatic and aliphatic hydrocarbons separation using ionic liquids
Authors: Graczová Elena , Steltenpohl Pavol , Šoltýs Martin , Katriňák Tomáš 
Published: November 2012

AbstractThe study concentrates on the separation of aromatic hydrocarbons from aliphatic hydrocarbon mixtures using ionic liquids as a new alternative of extraction solvents. Influence of the phase equilibrium description accuracy on the separation equipment design using different thermodynamic models was investigated. As a model system, a heptane-toluene binary mixture was chosen, employing 1-ethyl-3-methylimidazolium ethyl sulfate (EMIES) ionic liquid as an extractive solvent. Liquid-liquid equilibrium (LLE) data of the ternary system were calculated using NRTL equations with different quality model parameters. Model 1 corresponds to the NRTL equation with the original binary parameters evaluated independently from the respective binary equilibrium data. Model 2 is represented by an NRTL equation extended by the ternary correction term (with the original binary parameters and ternary correction term parameters evaluated from the ternary tie-lines). Model 3, i.e. the NRTL equation with binary model parameters determined via ternary LLE data regression using ASPEN Plus, was taken from Meindersma et al. (2006). Continuous-flow liquidphase extraction was simulated considering a cascade of mixer-settler type extractors according to the Hunter-Nash scheme (Hunter & Nash, 1934). Based on the simulation results, for a preset separation efficiency criterium, different accuracies of the equilibrium description caused serious discrepancies in the separation equipment design, e.g. in the number of theoretical stages, solvent to feed ratio, and product purity.
Salvaging a tooth by hemisection
Authors: Vikram M , Pai AR Vivekananda 
Published: November 2012

Introduction : Hemisection may be a valuable form of treatment for molar teeth when caries has progressed to the furcation, or where there is an extensive carious lesion extending subgingivally in one area of the root, making it impossible to place an adequate restoration in that area and the root is considered unrestorable. Case Presentation : When one of the roots of a multirooted teeth is beyond the scope of restoration, it becomes imperative to remove the diseased root. This case report is about the use of hemisection procedure which was carried out to salvage the mesial portion of the mandibular right first molar.Conclusion : The use of the procedure of hemisection can successfully eliminate the need for extraction of the whole tooth if only a part of it is unrestorable. Health Renaissance; September-December 2012; Vol 10 (No.3);251-253DOI: http://dx.doi.org/10.3126/hren.v10i3.7057
Lymphangioma circumscriptum - rare site
Authors: Kar S , Mohankar A , Krishnan A 
Published: November 2012

22 year old male came to Skin department with grouped vesicles over sternal region since birth along with serous discharge. The biopsy taken from site showed histopathologically Lymphangioma circumscriptum. It was treated with CO2 Laser, and response was good. Health Renaissance; September-December 2012; Vol 10 (No.3);256-257 DOI: http://dx.doi.org/10.3126/hren.v10i3.7059
Experimental and numerical investigation of the microstructural influence on the deformation behavior of notched cp-titanium specimens
Authors: Ruffing Christoph , Grad Patrick , Klassen Markus , Müller Ralf , Kerscher Eberhard 
Published: November 2012

Abstract
Notches lead to a decrease in the strength of machine parts in comparison to unnotched structures. The strength reduction is caused by stress concentration at the notch base. In static or dynamic calculations this effect is considered by the notch stress concentration factor. In this paper, simulations with a titanium single-crystal were carried out to analyze the dependence of the notch-stress concentration factor on the orientation of the anisotropic single-crystal material. Furthermore, numerical simulations and experiments with notched commercially pure titanium specimens have been performed to compare the stress–strain relationships until the ultimate tensile stress. The strain rate and grain size have been varied to identify dependencies on the microstructural situation which may influence the strength during the tests. After the tests, interrupted at ultimate tensile stress, metallographic sections were taken to reveal possible changes in microstructure. In the present investigation it is shown that for the single-crystal the notch-stress concentration factor depends strongly on the crystal orientation. Evidence is found that the grain size affects the strength of a notched specimen negatively, when the grain size is of the same size as the notch radius.
Presentation, management, and outcome of newly diagnosed glioblastoma in elderly patients
Authors: Tanaka Shota , Meyer Fredric B. , Buckner Jan C. , Uhm Joon H. , Yan Elizabeth S. , Parney Ian F. 
Published: November 2012

Object
Optimum management for elderly patients with newly diagnosed glioblastoma (GBM) in the temozolomide (TMZ) era is not well defined. The object of this study was to clarify outcomes in this population.

Methods
The authors retrospectively reviewed 105 consecutive cases involving elderly patients (age ≥ 65 years) with newly diagnosed GBM who were treated at the Mayo Clinic between 2003 and 2008.

Results
The patients' median age was 74 years (range 66–87 years), and the median Karnofsky Performance Status (KPS) score was 80 (range 40–90). Half of the patients underwent biopsy and half underwent resection. Patients with deep-seated lesions (19 patients [18%]) or multifocal lesions (34 patients [32%]) were more likely to have biopsy than resection (p = 0.0001 and 0.0009, respectively). New persistent neurological deficits developed in 7 patients (6.7%). Postoperative hemorrhage occurred in 6 patients (5.7%), all of whom underwent biopsy. Complete follow-up data regarding adjuvant treatment was available in 84 patients. Forty-one (49%) were treated with chemotherapy (mostly TMZ) and radiation therapy (RT), and 23 (27%) with RT alone. Nineteen (23%) received only palliative care after surgery (more common with biopsy, p = 0.03). Chemotherapy complications occurred in 28.6% (Grade 3 or 4 hematological complications in 11.9%). The median values for progression-free survival (PFS) and overall survival (OS) were 3.5 and 5.5 months. In a multivariate analysis, younger age (p = 0.03, risk ratio [RR] 0.34, 95% CI 0.13–0.89), single lesion (p = 0.02, RR 0.51, 95% CI 0.30–0.89), resection (p = 0.04, RR 0.54, 95% CI 0.31–0.94), and adjuvant treatment (p = 0.0001, RR 0.24, 95% CI 0.11–0.49) were associated with better OS. Only adjuvant treatment was significantly associated with prolonged PFS (p = 0.0007, RR 0.27, 95% CI 0.13–0.57). With combined therapy with resection, RT, and chemotherapy, the median PFS and OS were 8 and 12.5 months, respectively.

Conclusions
The prognosis for GBM worsens with increasing age in elderly patients. With important risks, resection and adjuvant treatment are associated with prolonged survival. Although selection bias cannot be excluded in this retrospective study, advanced age alone should not necessarily preclude optimal resection followed by adjuvant radiochemotherapy.
L'enfant rêvé : clinique d'un changement d'adresse
Authors: Bulat-Manenti Gorana 
Published: November 2012

Il arrive que l’enfant à qui l’on s’adresse ne soit pas tout à fait celui qu’on imagine... La cure avec une jeune femme démontre dans les détails de son déroulement qu’un travail analytique peut aboutir à un changement d’adresse. Un éclairage progressif d’un « angle mort », cause d’une adresse erronée, peut produire un changement d’angle d’approche et réduire l’écart entre l’enfant « rêvé » et l’enfant réel. Dans un va-et-vient entre l’universel de la théorie et le singulier de la clinique, la cure va valider ou invalider des hypothèses diverses et avancer grâce à la place faite au sujet, toujours singulier, différent de tout ce qui le précède.
Un vent d'ailleurs et d'ici
Authors: Chiang-Laluc Magnolia 
Published: November 2012

Le fait d’entrer dans un univers linguistique étranger induit chez certains enfants mutisme et inhibition. À travers une vignette clinique, nous assistons à la naissance du sujet à la parole par le travail de l’analyste en tant que « truchement » entre la mère et l’enfant.
Usages idéologiques et fantasmatiques du signifiant « équipe »
Authors: Henri Alain-Noël 
Published: November 2012

Résumé À partir d’une longue expérience de formation et de supervision auprès de praticiens de la régulation sociale, l’article aborde l’emploi du signifiant « équipe » dans sa double fonction idéologique et fantasmatique de masquage de contradictions spécifiques. Une brève enquête sur sa filiation sémantique, à partir du vocabulaire naval, montre un basculement entre la représentation d’un équipement humain, qui ne se distingue pas à l’origine d’un équipement matériel, vers celle d’un groupe coordonné de sujets de pratique. Ce qui renvoie à la contradiction entre modèles de sociabilité proto-industriels et néo-industriels. S’y ajoutent des contradictions inconscientes, plus nettement perceptibles dans les pratiques non productives : l’équipe est investie comme idéal du moi de la pratique, mais le paradoxe de l’appartenance – ce « nous » qui est à la fois pour chacun « moi » et « non-moi » – conduit à des arbitrages compliqués, qu’on éclaire de la comparaison avec le rapport entre les membres d’un couple parental et l’entité « couple ».
Le rôle du sport durant la Grande Guerre en Italie ou la mise en place d'un consensus nationaliste
Authors: Favero Jean-Pierre 
Published: November 2012

Résumé La pratique sportive durant la Grande Guerre en Italie est mise au service d’un nationalisme exacerbé par les interventionnistes et la presse sportive, en particulier La Gazzetta dello Sport . Le sport au début du conflit est pratiqué par la classe dirigeante, les officiers. Les paysans et les ouvriers jetés dans la tourmente découvrent la pratique sportive, notamment le football, en zone de guerre dès 1915. Suite aux mouvements insurrectionnels liés à la défaite de Caporetto en octobre 1917, les conditions de vie des soldats sont améliorées. La Gazzetta dello Sport aidée par les autorités militaires envoie des ballons de football et des gants de boxe au front, multiplie les rencontres sportives entre régiments mais aussi entre les nations de l’Entente. L’arditisme sportif s’inspirant des valeurs des corps francs : sang-froid, intrépidité, sens du sacrifice, est mis au service du nationalisme sportif lors des rencontres internationales, notamment les Jeux Interalliés de 1919. C’est un homme nouveau qui est mis en scène à la fin du conflit préfigurant la politique fasciste où le corps symbolise la virilité et l’action.
Autour des « Maries-Louises »
Authors: Largeaud Jean-Marc 
Published: November 2012

Résumé	L’armée napoléonienne repose sur le principe de la conscription mais en 1813-1814 les pertes subies à partir de la campagne de Russie et l’infériorité numérique de la Grande Armée obligent à une levée massive de classes d’âge de plus en plus jeunes ; on désignera sous l’épithète « Maries-Louises » les jeunes recrues de l’année 1815, mais dans quelles limites d’âge et dans quelle proportion ? Jean-Marc Largeaud donne un compte rendu détaillé des sources historiographiques disponibles, des variations départementales et de l’engagement réel de ces jeunes soldats sur le terrain. De fait, l’appellation elle-même est tardive, même si elle est attestée une première fois sous la plume du colonel Fabvier en 1819. Ce sont les romans d’Erckmann-Chatrian, l’ Histoire d’un conscrit de 1813 (1864) et Waterloo (1865), puis ceux d’Edward Montier Les Marie-Louises (1911) et d’Henri Houssaye 1814 (1888) qui lui donnent forme dans la littérature et c’est la guerre de 1914-1918 qui donnera un statut définitif à la représentation de la jeunesse en armes, héroïque et défenseur de la patrie.
Determining water quality parameters of aquifers in the Vientiane Basin, Laos, using geophysical and water chemistry data
Authors: Perttu Nils , Wattanasen Kamhaeng , Phommasone Khamphouth , Elming Sten‐Åke 
Published: November 2012

ABSTRACTThe aim of this study is to test the possibility of using magnetic resonance sounding (MRS) and vertical electrical sounding (VES) together with groundwater chemistry data from shallow and deep wells to distinguish freshwater aquifers from salt affected groundwater and moreover determine water quality parameters directly from geophysical data. Three study areas within the Vientiane Basin, including 46 sites and 38 sampled wells, have been chosen for the study. The main water quality parameters affecting the water conductivity in the Vientiane Basin are total dissolved solids (TDS) and hardness and to a minor extent chloride, which all have shown to have fairly high correlation to the electrical conductivity of groundwater. The resistivity of the aquifers is highly variable but is most often above 4 Ωm, suggesting fresh water. No wells in the investigated areas have water quality parameters exceeding the limit for unacceptable drinking or irrigation water. There is a fairly strong relationship between the conductivity of water from deep wells and the conductivity of the main water bearing layer determined by VES, where the best fit is obtained using: , . However, due to equivalence in the VES interpretation and the difficulty to estimate the resistivity contribution from finer sediments, the equation may be seen and used as guidance to good water quality only within the Vientiane Basin area or in other areas with similar geology. The MRS results have been used to identify water layers in the VES inversion results to decrease the uncertainty in the interpretation The combination of MRS and VES techniques has been successful in distinguishing high conductive clay and mudstone from water bearing layers and moreover freshwater aquifers from salt affected water. Altogether, this makes MRS and VES very promising tools for guidance of future drilling and water quality estimation.
Revision of the Canadian species ofAmauromyzaHendel (Diptera: Agromyzidae)
Authors: Boucher Stéphanie 
Published: November 2012

AbstractThe Canadian fauna of the genusAmauromyzaHendel (Diptera: Agromyzidae) is revised and contains 11 species:Amauromyza abnormalis(Malloch),A. angulicornisZlobin,A. flavifrons(Meigen),A. karli(Hendel),A. luteiceps(Hendel),A. nevadensisSpencer,A. pleuralis(Malloch),A. ripariaSehgal,A. scleriticaSpencer,A. shepherdiaeSehgal, andA.subinfumata(Malloch). Among these, three species (A. luteiceps,A. nevadensis, andA. scleritica) are here newly recorded in Canada andA. angulicornisnewly recorded in the United States of America. Other species are significantly more widespread in Canada than previously recorded. All species are redescribed and a new identification key to Canadian species is provided.
The effect of sex and maturation on cuticular semiochemicals in Monochamus scutellatus (Coleoptera: Cerambycidae)
Authors: Brodie Bekka S. , Wickham Jacob D. , Teale Stephen A. 
Published: November 2012

AbstractContact pheromones are a subset of a complex mixture of hydrocarbons secreted on the cuticle and play an important role in the mating behaviour of several cerambycid species (Coleoptera: Cerambycidae). In this study, we investigated the relationship between maturation (newly eclosed and sexually mature) adult Monochamus scutellatus (Say) beetles and sex and the composition of the cuticular hydrocarbon blend to determine if this information is encoded in the blend and potentially available for communication purposes. Whole-body extracts of unfed females, and both mature females and males were analysed by gas chromatography mass spectrometry to identify and quantify the components of the cuticular hydrocarbons. There were no unique compounds present in any of the three groups, but discriminant analysis indicated that the relative proportions of the cuticular hydrocarbon components were unique for each group.
Molecular Characterization of the Early B Cell Response to Pulmonary Cryptococcus neoformans Infection
Authors: Rohatgi Soma , Pirofski Liise-anne 
Published: November 2012

Abstract
The role of B cells in host defense against fungi has been difficult to establish. We quantified and determined the molecular derivation of B-1a, B-1b, and B-2 B cell populations in C57BL/6 mice after pulmonary infection with Cryptococcus neoformans. Total B-1 and B-2 cell numbers increased in lungs and peritoneal cavity as early as day 1 postinfection, but lacked signs of clonal expansion. Labeled capsular (24067) and acapsular (Cap67) C. neoformans strains were used to identify C. neoformans–binding B cell subsets by flow cytometry. Peritoneal cavity B-1a B cells exhibited the most acapsular and capsular C. neoformans binding in C. neoformans–infected mice, and C. neoformans–selected B-1 B cells secreted laminarin- and C. neoformans–binding IgM. Single-cell PCR-based sequence analysis of B-1a, B-1b, and B-2 cell IgH V region H chain (VH) genes revealed increased usage of VH11 and VH12, respectively, in acapsular and capsular C. neoformans–selected B-1a cells. Germline VH segments were used, with capsular C. neoformans–selected cells having less junctional diversity than acapsular C. neoformans–selected cells. Further studies in B-1 B cell–depleted mice showed that these mice had higher brain and lung fungal burdens and less alveolar macrophage phagocytosis of C. neoformans than did control and B-1a B cell–reconstituted mice. Taken together, these results establish a mechanistic role for B-1 B cells in the innate B cell response to pulmonary infection with C. neoformans and reveal that IgM-producing B-1a cells, which express germline VH genes, bind C. neoformans and contribute to early fungal clearance. Thus, B-1a B cells provide a first line of defense during pulmonary C. neoformans infection in mice.
Clinical Significance of Alk-1 Gene Abnormalities in Diffuse Large Cell Lymphoma
Authors: Korashy L. , El-Zawahry H. , Abdou S. , Shahin D. , Sherif F. , Farrag W. , Abdel-Khalik O. , Salem H. , El-Sebaaie A. 
Published: November 2012

Objectives To detect relative frequency of anaplastic lymphoma kinase (ALK-1) gene abnormality in diffuse large cell lymphoma (DLCL) using fluorescence in situ hybridization (FISH), and correlate its presence with clinicopathological features which may be useful for choice of therapy and predict survival in newly diagnosed cases. Patients and Methods A prospective study was done between March 2004 and October 2009. Fifty patients newly diagnosed with DLCL were enrolled into the study. Immunophenotyping was done and detection of ALK-1 gene abnormalities were carried out by immunohistochemically (IHC) and FISH. Patients that proved to be ALK-1 positive were treated with standard cyclophosphamide –hydroxydaunorubicin-oncovin-prednisone (CHOP) protocol. Results All ALK +ve patients achieved complete remission (CR) vs. 93.5% CR and 6.5% partial remission (PR) for ALK –ve patients respectively. Disease free survival (DFS) at 24 months was 81.8% in the CHOP-14 group (ALK-1−) vs. 100% for the CHOP-21 group (ALK-1+). Overall survival (OS) at 30 months was 80.4% in the CHOP-14 group vs. 100% for the CHOP-21 group.
Treatment of Macular Serous Neuroretinal Detachment in Tilted Disk Syndrome: Report of 3 Cases
Authors: Donati Maria Carla , Miele Alba , Abbruzzese Giacomo , Giuntoli Matteo , Giansanti Fabrizio , Menchini Ugo 
Published: November 2012

Purpose. To describe functional and anatomic results obtained by treatment with photodynamic therapy (PDT) or intravitreal bevacizumab (Avastin, Roche) in macular serous retinal detachment associated with tilted disk syndrome. Methods. Three eyes of 3 patients with symptomatic macular serous detachment associated with tilted disc syndrome (optic disc with an oblique axis, inferonasal crescent, and inferior staphyloma) were treated. In all patients, best-corrected visual acuity (BCVA) was tested and fluorescein angiography (FA) and optical coherence tomography (OCT) were performed before and about 45 days after treatment. All patients underwent a complete ophthalmologic examination including OCT at least 6 months after treatment. The first patient was treated with one low fluence (300 mW/cm2 for 83 seconds) PDT (6 months follow-up). The second patient was treated with 3 intravitreal injections of bevacizumab 1.25 mg (33 months follow-up) and the third patient was treated with 2 low fluence PDTs at 4 months and, after 1 year, 3 intravitreal injections of bevacizumab 1.25 mg (37 months follow-up). Results. Before treatment, all patients complained of visual loss and metamorphopsia. The OCT showed in the macular area a focal neurosensory detachment with foveal involvement. The FA showed in the macular area multiple focal areas of hyperfluorescence due to pigment epithelium atrophy and in the second and third patient also a hyperfluorescent pinpoint with minimal leakage. After treatment in all eyes, symptoms did not change, BCVA remained stable, and in OCT the foveal neuroretinal detachment was changeless. In FA, no noticeable variation of the hyperfluorescence areas was appreciated. In the second patient, the hyperfluorescent point remained unvaried, and the same occurred in the third patient after the first PDT, while after the second PDT a new leaking dot disappeared. Conclusions. Macular serous retinal detachment was first described in 1998 as an uncommon complication of tilted disc syndrome showing angiographic and OCT features similar to a chronic central serous chorioretinopathy. In contrast to this pathology, in our patients treatment with PDT or intravitreal bevacizumab did not succeed, probably because of a different pathogenesis of macular serous detachment. Further investigations are needed to clarify the proper therapy of this disease.