bluuebunny/crossref_metadata_2025_split huggingface dataset:
The rural CPR outreach project: Medical students teach bystander CPR to secondary school students
Authors: Bene Watts Simona , McDonagh Erin , Richardson Wesley , Wilson Nicholas , Shi Kevin 
Published: August 2024

Abstract

Introduction:
Prompt bystander cardiopulmonary resuscitation (CPR) can double the chance of cardiac arrest survival. Rural and remote communities experience longer emergency service wait times and have lower rates of bystander-CPR compared to their urban counterparts. Our study addresses this disparity.

Methods:
We designed a 1.5-h free hands-only CPR course tailored to secondary school students in rural and remote communities taught by medical students. We evaluated our course using pre-test and post-test surveys.

Results:
We taught over 300 secondary students in 5 days. Less than one-third of students had previously taken a CPR course. We found that brief CPR instruction taught by medical students was effective in both improving students’ knowledge of CPR (t[528] = −26, P < 0.01) and perceived comfort in performing CPR (t[548] = −12, P < 0.01).

Conclusion:
CPR courses taught by medical students are effective, low cost, and may help address regional health care disparities. Teaching CPR to rural/remote communities may have secondary benefits such as promoting health care careers to rural youth. We encourage other health professional programmes to consider engaging students in CPR outreach projects.

Introduction:
Une réanimation cardio-pulmonaire rapide peut doubler les chances de survie en cas d’arrêt cardiaque. Les communautés rurales et éloignées connaissent des temps d’attente plus longs dans les services d’urgence et ont des taux plus faibles de RCP par rapport à leurs homologues urbains. Notre étude porte sur cette disparité.

Méthodes:
Nous avons conçu un cours de RCP pratique et gratuit d’une heure et demie, adapté aux élèves du secondaire des communautés rurales et isolées et dispensé par des étudiants en médecine. Nous avons évalué notre cours à l’aide d’enquêtes pré-test et post-test.

Résultats:
En 5 jours, nous avons enseigné à plus de 300 élèves du secondaire. Moins d’un tiers des élèves avaient déjà suivi un cours de RCP. Nous avons constaté qu’une brève formation à la RCP dispensée par des étudiants en médecine était efficace pour améliorer les connaissances des élèves en matière de RCP (t[528] = −26, P < 0,01) et la perception de leur aisance à pratiquer la RCP (t[548] = −12, P < 0,01).

Conclusion:
Les cours de RCP dispensés par les étudiants en médecine sont efficaces, peu coûteux et peuvent contribuer à lutter contre les disparités régionales en matière de soins de santé. L’enseignement de la RCP aux communautés rurales/éloignées peut avoir des avantages secondaires tels que la promotion des carrières dans le domaine de la santé auprès des jeunes ruraux. Nous encourageons d’autres programmes professionnels de santé à envisager d’engager leurs étudiants dans des projets de sensibilisation à la RCP.
Utility of Keystone Flap in Armory of Dermatosurgeons
Authors: Singh Abhinav , Singh Rohini , Chaturvedi Gaurav , Singh Malika , Singh RB 
Published: August 2024

Abstract

Purpose and Background:
To create awareness among dermatosurgeons about the versatility of keystone flaps in re-surfacing post-excisional small, medium and large skin defects.

Aims and Objectives:
Single-staged tension-free re-surfacing of various sized skin defects using keystone flap and to have least donor site morbidity, primary healing and maximum functional outcome.

Material and Methods:
This retrospective study was conducted, between October 2021 – January 2023 in Department of Plastic Surgery, PGIMS Rohtak, on 15 males and 1 female aged between 18 - 65 years. Sixteen Keystone flaps (type IIA n=13, Omega cum Sydney melanoma unit modification n=3) were utilized for resurfacing skin defects arising after excision of basal cell carcinoma (n=3) and benign hairy nevus (n=2) on cheek, basal cell carcinoma forehead (n=1), electric burns on deltoid (n=2), giant neurofibroma back (n=1), tattoo forearm (n=3), chronic non-specific granuloma thumb (n=2) and pilonidal sinus disease (n=2). Skin with maximum expansibility was chosen as donor site with utmost care of facial lines and its aesthetic subunits. Flaps were dissected all around preserving maximum number of hand-held Doppler-identified perforators in pedicular area. Sutures were removed on 10th to 15th post-operative day. Follow-ups ranged from 2 to 15 months.

Results:
None had wound dehiscence or loss of flap.

Conclusion:
Keystone flaps have defect-adaptive design, simple bio-geometry, technical simplicity, decreased downtime, cost effectivity and efficiency and can be designed to resurface post-excisional skin defect from head to toe with acceptable results, therefore should strongly be considered by dermatosurgeons while excising skin lesions.
“Little by little, I started feeling I am unable to handle my child alone” – Lived experiences of mothers with postpartum depression and anxiety
Authors: Sridhar Harikrupa , Kishore M. Thomas , Chandra Prabha S. 
Published: August 2024

Background:Anxiety and depression during the postpartum period can have a significant impact on mothers’ perceived sense of responsive caregiving, causing considerable distress. This association may be affected by mothers’ perception about social support. In the context of low-and-middle-income countries where prevalence rates of maternal mental illnesses are high and access to health care services is limited, informal supports become more relevant.Aim:The study aims to understand the lived experience of mothers who had postpartum depression or anxiety and their perceived distress related to infant care giving. It also explores the role of social support in the motherhood experience.Methods:Six mothers with postpartum depression or anxiety were interviewed to understand their experience of postpartum depression and/or anxiety and their perceptions about social support. The interviews were analyzed using a reflexive thematic analysis approach.Results:The thematic analysis revealed four themes, namely, (a) uncertainty and helplessness, (b) misattunement with the immediate family, (c) personal strength rooted in the family support system, and (d) other means of coping. Mothers with postpartum anxiety and depression can have emotional, informational, and tangible social support needs in the context of uncertainty and helplessness, which are associated with different challenges and barriers for infant care in the Indian context.Conclusion:Support from family members is viewed as a pillar of comfort and recovery for the mothers. At the same time, if it is not adequately attuned to the needs of the mother, it can become a major source of distress.
Psychometric attributes of the Dimensional Yale-Brown Obsessive-Compulsive Scale adapted in Bengali: A validation study in the Bengali-speaking population
Authors: Kundu Partha S. , Halder Arghya , Pal Amit K. , Ray Sagarika , Mondal Sayan 
Published: August 2024

Introduction:
Obsessive-compulsive disorder (OCD) is characterized by underlying obsessions and yielding/nonyielding compulsions, which often leads to significant levels of distress for the individual. Recently, obsessive-compulsive symptoms have been grouped into various symptom dimensions. The Dimensional Yale-Brown Obsessive-Compulsive Scale (DY-BOCS) gives a comprehensive picture regarding symptom severity in each individual dimension of OCD, while also providing a global severity score.

Aims and Objectives:
The psychometric properties of the Bengali adaptation of DY-BOCS have been assessed in this study.

Material and Methods:
A cross-sectional study was performed on 80 individuals suffering from OCD as per the ICD-10 DCR criteria. The Bengali version of the DY-BOCS and other scales for OCD, anxiety, and depression were administered to all of them. Inter-rater reliability was assessed for 34 individuals, and agreement between self and clinician-rated version of DY-BOCS was studied for 60 individuals. Internal consistency for items in a particular dimension of DY-BOCS, convergent validity, and divergent validity were also assessed.

Results:
Internal consistency was found to be excellent (Cronbach’s α > 0.90 in all domains), and inter-rater reliability was found to be good to excellent for all the six dimensions of the DY-BOCS (intraclass correlation values >0.80 for aggressive and miscellaneous domains and >0.90 in all other domains). High correlation was found between self and clinician-rated versions of DY-BOCS for the age group 18–35 years, the highest correlations being found for the Contamination (r = 0.82) and Aggressive domains (r = 0.75), while it was found to decrease in the older age group. Convergent validity and divergent validity were found to be satisfactory.

Conclusion:
The psychometric attributes of the Bengali version of DY-BOCS appear to be satisfactory and thus can be reasonably administered to the population having Bengali as their mother tongue.
Efficacy of sequential primary motor and prefrontal cortices intermittent Theta burst stimulation in persistent somatoform PAIN disorder (TAP-PAIN): A randomized sham-controlled pilot trial
Authors: Joshi Shailja , Garg Shobit , Mishra Preeti , Dhyani Mohan , Tikka Sai Krishna 
Published: August 2024

Aim:
There is a need to elucidate intermittent Theta burst stimulation (iTBS) as a novel treatment in persistent somatoform pain disorder (PSPD).

Methods:
Twenty patients were randomly allocated to active iTBS (n = 11) and sham iTBS (n = 9) and received 10 iTBS sessions, 2 sessions per day, sequentially to primary motor and dorsolateral prefrontal cortices for 5 days in a week. Each iTBS session comprised of 2 sec. per train of 10 bursts (3 pulses per burst at 50 Hz; total 30 pulses) and were given with a gap of 5 Hz, total of 20 trains, and 600 pulses. Visual Analogue Scale, Brief Pain Inventory and Global Pain Scale (GPS), Montgomery and Asberg Depression Rating Scale, Hamilton Anxiety Rating Scale - Anxiety, World Health Organization Quality-of-Life Scale-brief, and Pittsburgh Sleep Quality Index were applied at baseline, after last session, and at 2 weeks after last TBS session. Intention to treat analysis was conducted.

Results:
Both groups were comparable for baseline psychopathology scores including clinical variables like age (t = 0.865; P = 0.398), duration of illness (t = 1.600; P = 0.127), and motor threshold (t = 0.304; P = 0.765). On repeated measures ANOVA, a significant within-group time effect for VAS, BPI-Severity, BPI-Interference, BDI – II, MADRS, HAM-A, and WHOQOL- BREF was found for active and sham TBS groups, respectively. GPS scores had significant within-group (active) * time interaction (F = 11.651; P = .001; ηp2 = 0.538) and between-group * time interaction (F = 3.407; P = 0.044; ηp2 = 0.159). However, between-group * time effect interaction was lost after covariance (F = 1.726; P = 0.196; ηp2 = 0.110).

Conclusion:
No major adverse effects were reported. Our pilot trial concludes that safe therapeutic efficacy of iTBS in PSPD is inconclusive. Lower total number of sessions along with small sample size may limit the study findings.
Anticancer and bioactivity effect of the AraA-IL13 fusion protein on the glioblastoma cell line
Authors: Mehrab Rezvan , Sedighian Hamid , Sotoodehnejadnematalahi Fattah , Halabian Raheleh , Imanifooladi Abbas Ali 
Published: August 2024

Background and purpose:
Glioblastoma (GBM) is an aggressive and malignant brain cancer with the highest mortality and low survival rates. To discover a more specific and efficient treatment for GBM, we synthesized and examined the cytotoxic effect of arazyme-interleukin-13 (Ara-IL13) fusion protein on GBM cells.

Experimental approach:
At first, the araA-IL13 chimeric gene in the pET28a (+) vector was designed and synthesized. After transformation into Escherichia coli BL21 (DE3), the chimeric gene was verified by colony polymerase chain reaction. Expression optimization and purification of the AraA-IL13 fusion protein was performed and subsequently evaluated by 10% SDS-PAGE. The protein was purified and concentrated using the Amicon® Ultra- 15 centrifugal filter unit. The presence of AraA-IL13 was investigated by the western blotting technique. The enzyme was evaluated for proteolytic activity after purification on skim milk agar. The cytotoxic effect of the AraA-IL13 fusion protein was evaluated by MTT assay on U251 and T98G cell lines in vitro.

Findings/Results:
The chimeric protein had no proteolytic activity on skim milk agar despite high expression. Furthermore, no cytotoxic effect of this fusion protein (up to 400 μg/mL) was observed on the U251 and T98G cell lines.

Conclusion and implications:
The lack of proteolytic activity and cytotoxic effect of AraA-IL13 may be due to the disruption of the three-dimensional structure of the protein or the large structure of the arazyme coupled with the ligand and the lack of proper folding of the arazyme to make the active site of the enzyme inaccessible.
Epidemiological Patterns, Risk Factors, and Outcomes in COVID-19 Patients from the Al-Hassa City of Saudi Arabia
Authors: Aleid Abdulsalam Mohammed , Ahmed Khadija Adel , Alhar Khalid Abdulrahim , Ma’ashi Esraa Yehea Hasan , Sonbul Yasseer Youssef , Alsuwat Khalid Jameel , Alfaraj Fatimah Baqer , Aljohani Ammar Mohammed , Alosaimi Hadeel Abdullah , Alshehri Abdulmohsen Ali , Aljarid Manar Yahya Saleh , Alalweni Bara Talal , Alghamdi Kheder Mabrook , Alqahtani Mansour Salem Ali , Almadani Noura Abdulla , Kharaba Ayman Mohammed 
Published: August 2024

Abstract

Background:
In the face of the ongoing global health crisis posed by COVID-19, it becomes imperative to understand the disease’s dynamics, particularly in specific regions. This study provides a detailed examination of the factors influencing mechanical ventilation (MV) duration among COVID-19 patients in an intensive care setting, focusing on a diverse patient cohort from the Al Hassa region of Saudi Arabia.

Objectives:
The primary aim of this study was to identify key demographic factors, clinical outcomes, and comorbidities that affect the duration of MV among intensive care unit (ICU) patients with COVID-19. This understanding is crucial for enhancing patient care and informing health-care strategies in the context of the pandemic.

Methods:
A retrospective cohort study was conducted involving patients diagnosed with COVID-19 and admitted to the ICU in the Al Hassa region. Data encompassed patient demographics, comorbidities, clinical outcomes, and MV duration. Statistical analyses were employed to explore the associations between these variables.

Results:
Our findings reveal significant associations between MV duration and various factors, including nationality, legal status, travel history, and comorbidities such as heart failure and immunocompromised status. These insights are instrumental in understanding the nuances of COVID-19 management in critical care.

Conclusion:
The study provides valuable insights into the determinants of MV duration in severe COVID-19 cases, emphasizing the need for individualized patient care approaches. It highlights the complexity of managing COVID-19 in ICU settings and underscores the importance of tailored health-care responses to this global health challenge, particularly in the Al Hassa region.
The prevalence, severity, and risk factors of erosive esophagitis in a Middle Eastern population
Authors: Alsahafi Majid , Salah Fatma , Mimish Hebah , Hejazi Mohammed , Alkhiari Resheed , Alkhowaiter Saad , Mosli Mahmoud 
Published: August 2024

Abstract

Background:
Erosive esophagitis (EE) is frequently present in patients with gastroesophageal reflux disease (GERD), some of which may not have GERD symptoms. The prevalence of EE in the Saudi population is unknown. In this study, we aimed to determine the prevalence and risk factors of EE among patients undergoing esophagogastroduodenoscopy (EGD).

Methods:
We retrospectively reviewed consecutive adults who underwent EGD at an academic tertiary care center. Clinical and endoscopic data were collected. The prevalence and severity of EE were determined. Multivariate regression analysis was used to identify risk factors for EE.

Results:
Records for 3230 patients were reviewed, of which 2805 were included in this study. The mean age was 48.6 ±18.6 years, and 1088 (38.7%) were male. Two hundred and twenty six (8%) patients underwent EGD for GERD-related indications. EE was noted in 309 (11%) patients and 58 (25.6%) with GERD-related indications. For patients with EE, the mean age was 49.2 ± 18.7 years, and 132 (42.7%) were males. LA Grade A esophagitis was the most common (53.9%), followed by grade B (29.6%). Among all patients, only EGD for GERD-related indications and hiatal hernia were significantly associated with EE on multivariate analysis [(aOR = 3.1, 95% CI 2.2–4.4, P < 0.01) and (aOR = 1.4, 95% CI 1.1–1.9, P < 0.01), respectively]. Age, gender, and body mass index were not associated with EE.

Conclusion:
In this large cohort, EE was present in 11% of patients who underwent EGD and in 25% of patients with GERD. EGD for GERD-related indications and hiatal hernia are independent risk factors for the presence of EE.
Tantangan Implementasi Pengakuan Hukum Adat dalam Kitab Undang-Undang Hukum Pidana Baru di Indonesia
Authors: Ramadhani Milenia 
Published: August 2024

KUHP Nasional atau KUHP Baru telah memberikan pengakuan terhadap hukum yang hidup (living law) sebagai asas legalitas materiil, sehingga selain melanggar perundangan, melanggar hukum adat juga dapat dipidanakan dengan ketentuan lebih lanjut. Penelitian ini bertujuan mengidentifikasi tantangan implementasi living law dalam KUHP baru agar dapat menjadi pedoman dan masukan para pemangku kepentingan. Penelitian ini merupakan penelitian normatif yang dipadukan dengan konsep dan teori sosial. Hasil penelitian menunjukan paling tidak ada 6 tantangan yang perlu disiapkan dalam implementasi KUHP baru terkait living law, yaitu 1) Perlu sesegera mungkin di bentuk Peraturan Pemerintah dan Peraturan Daerah yang mengatur terkait hukum yang hidup dalam masyarakat; 2) Perlu pelibatan Lembaga adat dalam pelaksanaan hukum adat; 3) Perlu diatur tentang hukum perselisihan antar adat; 4) Perlu adanya identifikasi hukum-hukum adat yang ada di Indonesia; 5) Perlu pembekalan hakim terhadap persoalan adat istiadat; 6) Perlu kepatuhan terhadap prinsip Hak Asasi Manusia, UUD NRI 1945 dan Pancasila
PENERAPAN METODE JIGSAW TERHADAP PENINGKATAN MINAT BELAJAR PENDIDIKAN AGAMA ISLAM DI KELAS XI MIPA 1 SMAN 3 MAJENE
Authors: Annida Indah Khofiyah  
Published: August 2024

Abstract
Currently, many students have little interest in Islamic Religious Education lessons even though Islamic Religious Education is very important to understand. One of the factors that causes students lack of interest in learning is because learning methods are monotonous and not varied. In this research, the Jigsaw method is expected to increase student’s interest in learning in Class XI MIPA 1 SMAN 3 Majene. The aim of this research is to find out what influence the Jigsaw method has on interest in learning Islamic religious education at XI MIPA 1 SMAN 3 Majene. The research method used is the Classroom Action Research (PTK) method and Library Research related to research. As a result, student’s interest in studying in class.
Keywords: Method, Learning, Jigsaw, Interest in Learning

Abstrak
Saat ini banyak peserta didik yang memiliki minat yang kurang terhadap pelajaran Pendidikan Agama Islam padahal PAI sangat penting untuk dipahami. Salah satu faktor yang menyebabkan kurangnya minat belajar peserta didik yakni karena metode pembelajaran yang monoton dan tidak bervariasi. Dalam penelitian ini, metode jigsaw diharapkan dapat meningkatkan minat belajar peserta didik di Kelas XI MIPA 1 SMAN 3 Majene. Tujuan penelitian ini adalah untuk mengetahui apa pengaruh metode jigsaw terhadap minat belajar Pendidikan agama islam di XI MIPA 1 SMAN 3 Majene. Metode penelitian yang digunakan adalah metode Penelitian Tindakan Kelas (PTK) dan Library Research yang terkait dengan penelitian. Hasilnya, minat belajar siswa Kelas XI MIPA 1 SMAN 3 Majene terhadap mata pelajaran PAI meningkat yang ditandai dengan hasil refleksi atau evaluasi di kelas.
Kata Kunci: Metode, Pembelajaran, Jigsaw, Minat Belajar
Measuring of Digital Banking Service Quality on Customer Satisfaction with Reference to Bengaluru
Authors: Prof Ashwini Basavaraju  , Prof Meghana C  , Prof Rashmi S  , Prof Lohith Kumar S  , Prof Rajendra Kumar V R  , Prof Vinay M  
Published: August 2024

Purpose: The study aims at adding to the existing knowledge of how service quality of Digital Banking has an influence on customer satisfaction of Banks in a Metropolitan City like Bengaluru. This will help Banks and policy makers to understand the internet banking dimension and its contribution to customer satisfaction. With the increased usage of Online banking services in India post COVID. India has emerged as the largest user of Online Payment system, there is an increased need to study the service quality of Digital Banking facility.
Design and Methodology: An exploratory survey was conducted with the help of Likert Scale Questionnaire conducted to investigate the impact of Digital Banking service quality on customer satisfaction in Bengaluru. Convenience sampling was used, and various kinds of Digital banking customers were approached in Bengaluru. Data was collected from a sample of 216DigitalBanking customers. Descriptive statistics, correlation, confirmatory factors analysis are used to analyze the data
Findings: The findings suggest that there is a noteworthy correlation between the characteristics of online banking service quality and the level of customer satisfaction among internet banking users. Customer satisfaction in online banking is attributed to each of the following dimensions: efficiency, system availability, fulfillment, privacy, contact, responsiveness, and contact.
Implication of the Study: The Research will help bank Managers, policy makers to focus on these factors which have a great impact on satisfying the customers which will result in better service quality of Digital Banking services which ensure greater usage of banking services and prosperity resulting in greater number of transactions benefiting the economy.
Upaya Guru Bimbingan Konseling Disekolah Man 2 Deli Serdang Dalam Mengatasi Kejenuhan Belajar Siswa Dikelas
Authors: Nur Azizah  , Khaliza Nur Fazar  , Fahmi Ramdhan Purba  , Dessy Fitasari  , Fauziah Nasution  
Published: August 2024

Penilitian ini bertujuan untuk mengatasi kejunuhan belajar siswa dikelas pada Siswa/I MAN 2 DELI SERDANG dengan menggunakan ice breaking.Kejenuhan belajar adalah keadaan seseorang ditandai dengan letih,tidak bersemangat,serta bosan dalam mengikuti kegiatan belajar mengajar didalam kelas,dengan adanya ice breaking pada saat jam pelajaran membuat siswa dapat kembali bersemangat dalam mengikuti pembelajaran dikelas.Metode penelitian ini menggunakan metode observasi serta wawancara dengan dari seluruh siswa /I yang ada di sekolah MAN 2 DELI SERDANG.Teknik yang digunakan yaitu teknik kualitatif.Hasil dari penelitian ini adalah (1) Cara Siswa dalam mengatasi kejenuh pada saat jam pelajaran berlangsung siswa tersebut permisi keluar kelas untuk pergi kekantin (2) Cara siswa dalam mengatasi kejenuhan pada saat jam pelajaran dengan permisi ke toilet untuk merokok (3) Cara siswa dalam mengatasi kejenuhan pada saat jam pelajaran berlangsung dengan cara bermain game di lapangan sekolah.