bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sexuality in female patients on hemodialysis: a scoping review protocol
Authors: Imhof Solange , Nerbass Fabiana Baggio , Ribeiro Heitor S. , Santos Rafaela Gonzaga dos , Nilson Luana Gabriele 
Published: August 2024

Sexuality is a human biological function that is not limited only to genitality but to total corporeality. Sexual function is a complex biopsychosocial phenomenon in which internal and external stimuli are modulated by the central and peripheral nervous system, resulting in biochemical, hormonal, and circulatory changes that culminate in physical and cognitive sexual results. Several conditions influence sexuality, and one of the diseases that can impair female sexual function and impact sexuality is chronic kidney disease. Considering the complexity and specificity of chronic kidney disease, the significant repercussions of hemodialysis treatment on the lives of patients, and the scarce scientific production, the need to delve deeper into the topic was perceived since the experience of sexuality of these women is relevant in the quality of life and not usually addressed by health professionals. To investigate the topic in-depth, a scoping review will be developed on the sexuality of female people undergoing hemodialysis treatment, regardless of their sexual orientation. The objective of this work is to map the production of knowledge about sexuality in women undergoing hemodialysis treatment. The search for publications will be carried out in the following databases and bibliographic index: Medical Literature Analysis and Retrieval System Online (MEDLINE via PubMed), Web of Science, in the Bibliographic Index of Latin American and Caribbean Literature in Health Sciences (LILACS) and APA PsycNet. In addition to these databases, the research will also include gray literature, such as Google, Google Scholar, and YouTube. The question that will guide the review is: "What is the current knowledge about sexuality in women on hemodialysis? The review will consider studies that include the terms "sexuality", "women" and "hemodialysis", without restrictions on language and date.
Coronavirus Disease 2019 (COVID-19) Vaccination Status Prior to Delivery and Administration Among Hospitalized Obstetric Patients
Authors: Michelson Lisa P. , Beckham A. Jenna 
Published: August 2024

Background This chart review aimed to assess the COVID-19 vaccination status of pregnant patients prior to hospitalization for delivery and vaccine administration while hospitalized postpartum. Methods This was a retrospective chart review of pregnant patients admitted for delivery at WakeMed Hospital during a six-month period who were offered COVID-19 vaccination immediately following delivery. We analyzed demographic characteristics by vaccination status prior to admission, during hospitalization, and at discharge. ANOVA, chi-squared, and multinomial logistic regression analyses were performed. Results Data analysis was performed on 1,476 obstetric patients admitted for delivery, of which 260 (17.6%) were vaccinated prior to admission. Of the 1,216 unvaccinated postpartum patients, 257 (21.1%) received a vaccine dose. Among our population, for every year increase in age, the odds of being vaccinated before admission and receiving vaccination while hospitalized postpartum were higher than those of remaining unvaccinated. The odds of being vaccinated before admission versus remaining unvaccinated at discharge were lower for Black patients compared to White patients. The odds of receiving vaccination during hospitalization were higher for Asian and Hispanic/ Latino patients compared to White patients. The odds of being vaccinated prior to admission versus remaining unvaccinated at discharge were higher for those with private insurance compared to those with public insurance. Limitations At the time of our intervention, we did not collect data on COVID-19 infection status of the patient at the time of admission. Additionally, vaccination counseling and administration had not been added to standardized order sets, thus variations in counseling by providers may have impacted patient acceptance. Conclusions Compared to patients who remained unvaccinated following discharge, patients vaccinated prior to admission were more likely to be older with private insurance, and less likely to be Black, while patients vaccinated during hospitalization once postpartum were more likely to be older and either Asian or Hispanic/Latino.
Conventional all ceramic crowns versus CADCAM all ceramic laminates for esthetic rehabilitation of teeth with dental fluorosis: A 5 year follow-up study
Authors: Kapri Anita , Jacob Oliver , Rana Varun , Reddy Kiran , Kumari Pushpa , Rathi Akshi 
Published: August 2024

Every individual wants to look good and have a pleasing smile. In this era of social media where each and every phase of one’s life is captured in camera, having an unpleasant smile makes a huge negative psychological impact on every individual. The foremost reason of an unesthetic smile commonly is dental fluorosis. Dental Fluorosis is an abnormality that causes enamel discolouration which may result when excess fluoride is consumed during the teeth forming stage i.e. 8 years and younger. The effect remains lifelong resulting in a huge esthetic insult. Treating such patients with aesthetic all ceramic crowns and veneers will definitely improve the patient’s self-esteem. In this retrospective study we clinically evaluated the aesthetics and patient satisfaction of 2 different treatment modalities for dental fluorosis namely Conventional all ceramic crowns and CADCAM all ceramic laminates in teeth with anterior fluorosis. Patients were divided in two groups. Both the groups included 35 patients each, Group 1 received conventional all ceramic crowns (156 in anterior maxilla and 24 in anterior mandible) using IPS e max fabricated in porcelain furnace and Group 2 received CADCAM porcelain laminate veneers (144 in the anterior maxilla and 36 in the mandible) fabricated with incisal overlap technique that covered the incisal edge and part of the palatal/lingual side of the tooth with a 1 mm high palatal bevel. The Orofacial Aesthetic Scale (OES) was used to assess the overall satisfaction level and White Aesthetic Score was used to assess the overall aesthetic improvement post treatment in both the groups. On the basis of the OES, it was found that CADCAM all ceramic laminates was more satisfying treatment for the patient rather than more extensive conventional all ceramic crown preparation. WES scores suggest that conventional all ceramic crown gives more aesthetic results as compared to CADCAM all ceramic laminates in moderate fluorosis. The results of this clinical study should encourage clinicians to consider CADCAM all ceramic veneers over Conventional all ceramic crown restorations when restoring the smile of patients with moderate fluorosis.
Comparative evaluation of the fracture resistance of different core build up materials – An ex vivo study
Authors: Rajput Renu , Singh Anshdeep , Gupta Pulkit , Dhingra Anil , Dixit Seema , Grover Sheetal 
Published: August 2024

The aim of this study was to evaluate and compare the fracture resistance of ParaCore, luxacore, multicore in permanent anterior teeth using universal testing machine. Eighty recently extracted intact caries free Human Permanent Mandibular Premolars and disinfected according to CDC guidelines on infection control in dental health-care setting 2003. The teeth were then randomly assigned to four groups on the basis of material used (Group A – Multicore, Group B – Luxacore, Group C – Paracore, and Group D – control group, without any core buid up), each group consisting of 20 samples. The dentin surface was treated with the respective adhesives of the groups and then bulk filled with core build-up materials. The attained samples were than subjected to shear loading in Instron Universal Testing Machine. The data were tabulated and statistically analyzed using analysis of variance, Tukey’s HSD test. MultiCore material had the greatest fracture resistance followed by Group B and then group C. The least strength exhibited was by Group D – Control group preceded by Group A – ParaCore. MultiCore showed the highest fracture resistance followed by Luxacore, ParaCore, and control group
Vocational High School Teachers’ Perception of Project-based Learning Method in English Language Teaching: A Case Study
Authors: Tanila Melvira , Sulastini Sri , Agustina Imas Wahyu 
Published: August 2024

As Vocational High School (VHS) students are prepared to work in certain fields, project-based learning (PjBL)becomes one of the teaching and learning methods that teachers can use to meet the expectations in the work field. Even though the effectiveness of PjBL implementation is related to how the teacher perceives the method, less attention is given to studies that focus on teachers' perception of the principles of PjBL. Therefore, this study aimed to investigate the English teachers' perception of the PjBL method in terms of the objectives, principles, and teachers' roles. The descriptive case study was employed as the research design to answer the formulated research questions. Semi-structured interviews with English teachers at SMKN 26 Jakarta were conducted to collect the data. The findings show that all teachers have a good perception of the objectives of the PjBL method. Most teachers fully understand their role in the PjBL method. However, there was some misunderstanding in teachers' perception of the principle of challenging problem/question and public product. 75% of the teachers did not see sustained inquiry and reflection as the principle of the PjBL method. Therefore, teacher professional development training related to the principles of the PjBL method needs more attention.
Intrauterine Adhesions Repair with Menstrual Blood-derived Mesenchymal Stem Cells via CXCL13-CXCR5 Signal Axis and its Mechanism
Authors: Luo Bing , Zeng Xun , luo li 
Published: August 2024

Abstract

Backgroud:
Intrauterine Adhesions (IUA) is a common gynecological disease which is seriously endangers the reproductive function of women without any ideal treatment. Some researchers found Menstrual Blood-derived Mesenchymal Stem Cells (MenSCs) can repair of damaged endometrium, however, has not been fully clarified. This study aims to evaluate the therapeutic effects of MenSCs in IUA and the repair mechanism in vivo.
Methods
This study is Laboratory-based study. To evaluate the therapeutic effects of MenSCs in IUA, We cultivated MenSCs, established mouse endometrial injury model, observed the uterine morphology and degree of endometrial fibrosis and compared the expression of CXC chemokine ligand-13 (CXCL13)、CXC chemokine receptor-5 (CXCR5)、Plasmin Activating Inhibitor-1(Pai-1), Transforming Growth Faction-β1(TGF- β1) and Matrix Metalloproteinase-9 (Mmp-9) among each groups. GraphPad Prism 8.0 was used for statistical processing. Data were expressed as mean ± SD. Statistical comparisons among groups were performed with one-way ANOVA. P < 0.05 were considered statistically significant.
Results
We successfully cultured and identified MenSCs and established mice model of uterine adhesion. After treatment with MenSCs, endometrial morphology of mice was partially restored, endometrial thickness was increased, and glands were multipiled. The concentrations of CXCL13 and CXCR5 were significantly increased by immunofluorescence detection compared with the control group. The results of RT-qPCR showed that the expressions of Pai-1 and Mmp-9 were significantly lower than those of the control group.
Conclusions
MenSCs may reduce endometrial fibrosis and the down-regulating expression of Pai-1、Mmp-9 and CXCL13-CXCR5 axis were involved in the process of MenSCs repaired IUA.
Electroacupuncture Suppresses Premature Ventricular Complexes Occurring Post-myocardial Infarction through corticothalamic circuit
Authors: CAI ronglin , ZHANG Fan , WANG Qian-yi , Zhu Xia , WU Li-bin , SHU Qi , CHANG Hui-min , WU Yan , SHAO Wen-jing , WEI Xia , ZHOU Xiang , ZHOU Jie , LUO Zheng-jie , YANG Liu , DUAN Wen-xiu , ZHANG Bin , HU Ling , YU Qing , Zhang Zhi 
Published: August 2024

Abstract

Electroacupuncture (EA) has been shown to suppress premature ventricular complexes (PVCs) following myocardial infarction (MI) in humans. However, the specific neural circuitry and causal mechanisms underlying this effect remain unclear. Here, we reveal a previously unrecognized connection from the primary motor cortex (M1) to the nucleus rostral ventrolateral medulla (RVLM) circuitry via the layer 5 of the primary motor cortex (M1L5)-zona incerta (ZI) pathway, which selectively suppresses PVCs in post-MI mice. Utilizing viral tracing, fiber photometry recordings, and optogenetic stimulation, we demonstrate that EA inhibits glutamatergic projections from M1L5 to ZI, leading to the activation of local GABAergic neurons and subsequent inhibition of RVLM (M1L5-ZI-RVLM). Furthermore, optogenetic or chemogenetic inhibition of the M1L5-ZI-RVLM circuit replicates the anti-PVC effects observed with EA in MI mice. Artificial activation of M1L5-projecting ZI neurons reverses the suppressive effects of EA on PVCs in MI mice. Overall, our findings highlight the M1L5-ZI-RVLM circuit as a crucial mediator of EA-induced suppression of PVCs following myocardial infarction. Additionally, this newly identified corticothalamic circuit may represent a promising target for mitigating PVCs post-myocardial infarction.
Adsorption of CaAl-LDH for Cd2+ and its passivation on Cd-contaminated farmland around electroplating and metal processing industry cluster area
Authors: LU Xin-zhe , BAO Jia-yu , CAO Lan-yu , HUANG Chun-lei , ZHANG Jian-yu , ZHANG Xu-chuan , SUN Rui , LIU Yan-liang , ZHONG Nan-chong , LIU Jiacheng , WEI Ying-chun , WANG Xiao-zhi 
Published: August 2024

Abstract

The enrichment of heavy metal Cd in farmland soil results in significant harm to agricultural products, yet its removal poses considerable challenges. CaAl-layered double hydroxide (CaAl-LDH), a category of layered bimetallic composite hydroxides, is characterized by high efficiency, cleanliness, and stability in soil remediation. In this study, a CaAl-LDH adsorption experiment was conducted, and Cd-contaminated farmland surrounding a typical hardware processing enterprise was selected for a field trial using CaAl-LDH to passivate Cd in the soil. Alterations in Cd forms in soil and Cd content in rice were continuously monitored over three consecutive years to investigate the passivation effect of CaAl-LDH on Cd-contaminated farmland. The results indicated that the absorption of Cd2+ by CaAl-LDH adhered to a pseudo-second-order kinetic and the Langmuir model. At a pH of 6, CaAl-LDH's maximum adsorption capacity for Cd2+ reached 469.48 mg kg–1. Compared to fields treated with CaAl-LDH, a greater proportion of ion-exchange state Cd in rhizosphere soil transitioned to residual state and Fe-Mn bound state Cd, significantly reducing Cd content in rice grains. Continuous in-situ monitoring revealed that Cd content in rice grains treated with CaAl-LDH decreased by over 37% in the second year.
Effects of Personalized Meals on Quality of Life in Adult Cancer Patients Who Experience Chemotherapy-Induced Taste Alterations
Authors: Geurden Bart , Wijngaert Lobke Van den , Boeren Peter , Goossens Edwig , Adriaenssens Jef , Vandecandelaere Pieter 
Published: August 2024

Abstract

Purpose: This study aimed to assess whether the application of selective taste steering (STS) to personalize bread and soup recipes had any effect on (1) quality of life, (2) the palatability of these meals, and (3) food intake in patients with chemotherapy-induced taste alterations (CiTA).
Methods: This multicentre controlled before-and-after study included two groups of adult cancer outpatients who all experienced CiTA. Both groups received dietary advice as standard care. In one group, STS was applied to bread and soups at home for three months. Both groups were compared using validated scales and a structured questionnaire, at the start of the study and after 1 and 3 months of follow-up.
Results: A total of 19.3% of all patients (N=160) had a normal nutritional status (MNA-SF score >11). Compared to that in the intervention group, the number of patients with undernutrition (MNA-SF score <8) in the control group increased after 1 month (p <0.001) and 3 months (p <0.001) of follow-up. Compared to those in the control group, the 'fatigue', 'nausea/vomiting' and ‘diarrhoea’ symptom scores in the intervantion group decreased significantly (p <0.001, <0.001 and 0.002, respectively). In the intervention group, the score for 'appetite loss' decreased after 1 month (p <0.001) and remained low after 3 months of follow-up (p <0.001).
Conclusion: STS translates into a significant decrease in the loss of appetite and an increase in palatability and intake of personalized bread and soups. These findings are clinically relevant and support this innovative approach to malnutrition in cancer patients.
Climate-driven succession in marine microbiome biodiversity and biogeochemical function
Authors: Larkin Alyse A. , Brock Melissa L. , Fagan Adam J. , Moreno Allison R. , Gerace Skylar D. , Lees Lauren E. , Suarez Stacy A. , Eloe-Fadrosh Emiley A. , Martiny Adam 
Published: August 2024

Abstract

Seasonal and El Niño-Southern Oscillation (ENSO) warming result in similar ocean changes as predicted with climate change. Climate-driven environmental cycles have strong impacts on microbiome diversity, but impacts on microbiome function are poorly understood. We quantified changes in microbial genomic diversity and functioning over 11 years covering seasonal and ENSO cycles at a coastal site in the southern California Current. We observed seasonal oscillations between large genome lineages during cold, nutrient rich conditions in winter and spring versus small genome lineages, including Prochlorococcus and Pelagibacter, in summer and fall. Parallel interannual changes separated communities depending on ENSO condition. Biodiversity shifts translated into clear oscillations in microbiome functional potential. Ocean warming induced an ecosystem with less iron but more macronutrient stress genes, depressed organic carbon degradation potential and biomass, and elevated carbon-to-nutrient biomass ratios. The consistent microbial response observed across time-scales points towards large climate-driven changes in marine ecosystems and biogeochemical cycles.
Numerical simulation of the time-domain evolution characteristics of seismic waves for advanced detection of adverse geology in tunnels
Authors: Zhang Peng , Wang Jing , Ba Xingzhi , Li Xingyuan , Li Li-ping , Ni Jian 
Published: August 2024

Abstract

Identification of adverse geological bodies in front of the tunnel excavation face is essential to take precautionary measures for safer tunnel construction. Nowadays, the interpretation of seismic data in tunnels relies more on experience, which is caused by the lack of understanding of the propagation mechanism of seismic waves in tunnels. Therefore, based on the finite element method of seismic wave in two-phase medium, we investigate the time-domain evolution characteristics of seismic wave in tunnel space with two typical adverse geologic bodies, namely, water-bearing fracture zones and lithological interfaces. The results show that under the combined influence of solid-solid and solid-fluid phase reflections, the propagation complexity of the seismic wave is significantly increased, and the obvious diffraction phenomenon caused by tunnel face plays a promoting role. The amplitude attenuation of the waves obtained from the self-defined factor is exponentially related to the propagation time, which is influenced by the energy difference of the wave itself and the degree of wave crosstalk in the propagation process. This study can provide theoretical guidance for the technological development and field application of tunnel geological detection.
Identification of Phase Angle and Triglyceride-Glucose Index as Biomarkers for Prediction and Management of Diabetic Foot Disease
Authors: CLIMENT ESTHER SOLER , Rico Loreto Lledó , Poblet Marta García , Sopedra Isabel , Junquera-Godoy Isabel , Martinez-De-Juan Jose Luis , Gomis-Tena Julio , Saiz Javier , Prats-Boluda Gema , Pérez Remedio Santoyo 
Published: August 2024

Abstract

Introduction:
Approximately 25% of diabetic patients develop diabetic foot ulcers (DFUs), which significantly increase morbidity, mortality, and healthcare costs. Effective control and prevention are crucial to mitigate these impacts.
Objective
This study aims to identify easily measurable parameters for predicting DFU risk in routine consultations by assessing the correlation between Phase Angle (PA) and the Triglyceride-Glucose (TyG) index with DFU risk, based on their known association with diabetes.
Materials and Methods
A comparative observational case-control study was conducted at the General Hospital of Elche from March to June 2023, with 70 participants: 33 with diabetes and 37 without. Inclusion criteria for the case group were a diabetes diagnosis for over five years and a diabetic foot risk grade of 0, 1, or 2 according to the 2019 IWGDF stratification system. Exclusion criteria included inability to walk, prior use of plantar orthoses, and severe complications like edema or wounds. Predictive variables included PA, TyG index, body composition, and biochemical markers. Pearson or Spearman tests were used for correlations, Student's t-test or Mann-Whitney test for group comparisons, and one-way ANOVA or Kruskal-Wallis tests for normally and non-normally distributed variables, respectively.
Results
PA and TyG index were strongly linked to diabetic foot risk, supporting their potential as biomarkers. We confirmed the correlation between PA, TyG index, and diabetic foot risk, along with their significant relationships with other relevant biomarkers, enhancing our understanding of the condition.
Conclusion
PA and TyG index are valuable, easily measurable biomarkers for diabetic foot risk assessment. Their use in clinical practice could improve the management of diabetic complications, especially in resource-limited settings.