bluuebunny/crossref_metadata_2025_split huggingface dataset:
Advanced NDE Techniques and Their Deployment on High Pressure Equipment
Authors: Milligan Jeffrey P. , Peters Daniel T. , Van Velsor Jason K. 
Published: August 2013

Many advances in Non-Destructive Examination (NDE) have occurred in recent years. Some of these are becoming common in typical industry applications and are slowly migrating their way into niche industries, such as high-pressure applications. These advanced NDE techniques include the use of Linear Phased Array (LPA) ultrasonic examination for volumetric examination and Eddy Current Array (ECA) technology for surface examination. Advancements in ultrasonic Guided Wave Testing (GWT) also show promise for the examination of long tubes, such as in tubular low density polyethylene (LDPE) reactors. Effective deployment and delivery of these advanced techniques is critical to the collection and analysis of the inspection data.
Common challenges found in high-pressure equipment include access issues such as small diameter deep bores, large and thick section components, weld overlays and examination of thick section welds, complex geometries, and small crack sizes required for detection due to materials and design.
Applying these modern techniques in new designs and updating of in-service inspection plans for this high-pressure equipment can lead to a more accurate assessment of the equipment’s fitness for continued service, reduced maintenance costs, proper asset management of key capital equipment, and reduced turn-around time.
Comparison of Plant Life Management Approaches for Long Term Operations
Authors: Nuzzo Frank , Kang Ki-Sig 
Published: August 2013

Many Member States of the International Atomic Energy Agency (IAEA) have given high priority to long term operation of nuclear power plants beyond the timeframe originally anticipated (e.g. 30 or 40 years). Out of a total of 445 (369 GWe) operating nuclear power plants, 349 units (297 GWe) have been in operation for more than 20 years (as of November 2011) and many are engaged in investigations and studies aimed at prolonging the plant service life. The need for engineering support to operation, maintenance, safety review and life management for long term operation as well as education and training on LTO issues is increasingly evident. Plant life management (PLiM) techniques that can be defined as the integration of ageing and economic planning, have been used in operating nuclear power plants to maintain a high level of safety, optimize performance and justify long term operation (LTO) beyond the plant design life. In addition, as a follow up to the Fukushima accident, operators have become even more attentive to beyond design basis measures in the preparation of their plants for operation beyond their design life.
In many countries, the safety performance of NPPs is periodically assessed and characterized via the periodic safety review (PSR) process. Regulatory review and acceptance of PSRs constitutes for these countries the licensing requirement for continued operation of the plant to the following PSR cycle (usually 10 years). In the USA and in other countries operating US designed plants, instead of a PSR process, a license renewal application (LRA) process is followed, which requires certain pre-requisites such as ageing management programmes, particularly for passive irreplaceable systems structures and components (SSCs). Active components are normally addressed via the maintenance rule (MR) requirements and other established regulatory processes. A third group of Member States have adopted a combined approach that incorporates elements of both the PSR process and selected LRA specific requirements, such as time limited ageing analysis.
Taking into account this variety of approaches, the IAEA initiated work to collect and share information among Member States on good practices in plant life management for long term operation in nuclear power plants, by comparing the various approaches to the PSR reference and by drawing lessons learned from relevant applications and experiences.
Summary of Finite Element (FE) Sensitivity Studies Conducted in Support of the NRC/EPRI Welding Residual Stress (WRS) Program
Authors: Kerr Matthew , Rathbun Howard J. 
Published: August 2013

The U.S. Nuclear Regulatory Commission (NRC) and the Electric Power Research Institute (EPRI) are working cooperatively under an addendum to the ongoing memorandum of understanding to validate welding residual stress (WRS) predictions in pressurized water reactor (PWR) primary cooling loop components containing dissimilar metal (DM) welds. These stresses are of interest as DM welds in PWRs are susceptible to primary water stress corrosion cracking (PWSCC) and tensile weld residual stresses are the primary driver of this degradation mechanism. The NRC/EPRI weld residual stress (WRS) analysis validation program consists of four phases, with each phase increasing in complexity from laboratory size specimens to component mock-ups and ex-plant material.
This paper focuses on Phase 2 of the WRS program that included an international Finite Element (FE) WRS round robin and experimental residuals stress measurements using the Deep Hole Drill (DHD) method on pressurizer surge nozzle mock-up. Characterizing variability in the round robin data set is difficult, as there is significant scatter in the data set and the WRS profile is dependent on the form of the material hardening law assumed. The results of this study show that, on average, analysts can develop WRS predictions that are a reasonable estimate for actual configurations as quantified by measurements. Sensitivity studies assist in determining which input parameters provide significant impact on WRSs, with thermal energy input, post-yield stress-strain behavior, and treatment of strain hardening have the greatest impact on DM WRS distributions.
Draft Genome Sequence of
Euryhalocaulis caribicus
Strain JL2009
T
, a New Member of the Family
Hyphomonadaceae
Isolated from the Caribbean Sea
Authors: Zhang Yao , Zhao Zihao , Deng Wenchao , Xie Xiabing , Jiao Nianzhi 
Published: August 2013

ABSTRACT

Euryhalocaulis caribicus
strain JL2009
T
is a novel genus and species of the family
Hyphomonadaceae
and was first isolated from surface water in the Caribbean Sea. Here, we report the first draft genome from this genus. Its genome contains genes encoding proteins that are involved in organic acid metabolism and probable low-affinity inorganic phosphate transporters, which suggests its competence in oligotrophic oceans.
Whole-Genome Sequence of Fish-PathogenicMycobacteriumsp. Strain 012931, Isolated from Yellowtail (Seriola quinqueradiata)
Authors: Kurokawa Satoru , Kabayama Jun , Nho Seong Won , Hwang Seong Don , Hikima Jun-ichi , Jung Tae Sung , Kondo Hidehiro , Hirono Ikuo , Takeyama Haruko , Aoki Takashi 
Published: August 2013

ABSTRACTThe genusMycobacteriumcomprises a large number of well-characterized species, several of which are human and animal pathogens. Here, we report the whole-genome sequence ofMycobacteriumsp. strain 012931, a fish pathogen responsible for huge losses in aquaculture farms in Japan. The strain was isolated from a marine fish, yellowtail (Seriola quinqueradiata).
Genome Sequence of Bovine Viral Diarrhea Virus Strain 10JJ-SKR, Belonging to Genotype 1d
Authors: Joo Soo-Kyung , Lim Seong-In , Jeoung Hye-Young , Song Jae-Young , Oem Jae-Ku , Mun Seong-Hwan , An Dong-Jun 
Published: August 2013

ABSTRACT
Here, we report the complete genome sequence of a bovine viral diarrhea virus (BVDV) belonging to genotype 1d, strain 10JJ-SKR, which was isolated from cattle. The complete genome is 12,267 nucleotides (nt) in length, with a single large open reading frame. This is the first report of a BVDV belonging to genotype 1d and will enable further study of the molecular and epidemiological characteristics of this virus.
Draft Genome Sequence of Pseudomonas stutzeri Strain B1SMN1, a Nitrogen-Fixing and Naphthalene-Degrading Strain Isolated from Wastewater
Authors: Busquets Antonio , Peña Arantxa , Gomila Margarita , Mayol Joan , Bosch Rafael , Nogales Balbina , García-Valdés Elena , Bennasar Antonio , Lalucat Jorge 
Published: August 2013

ABSTRACT

Pseudomonas stutzeri
strain B1SMN1 is a naphthalene-degrading and simultaneously nitrogen-fixing strain isolated from a wastewater sample taken at a lagooning treatment plant in Menorca (Balearic Islands, Spain). Here we report the draft genome sequence of
P. stutzeri
B1SMN1. It is composed of a chromosome of an estimated size of 5.2 Mb and two plasmids of 44,324 bp and 56,118 bp.
Genome Sequence of Serratia plymuthica Strain S13, an Endophyte with Germination- and Plant-Growth-Promoting Activity from the Flower of Styrian Oil Pumpkin
Authors: Müller Henry , Fürnkranz Michael , Grube Martin , Berg Gabriele 
Published: August 2013

ABSTRACT

The bacterium
Serratia plymuthica
strain S13 was demonstrated to colonize various plant-associated microhabitats and to suppress damping-off diseases. The completed genome sequence has a size of 5.5 Mb, containing 4,957 putative protein-encoding regions, and will be used to identify genetic determinants enabling the bacterium to escort a plant's entire life cycle.
Draft Genome Sequence of
Exiguobacterium pavilionensis
Strain RW-2, with Wide Thermal, Salinity, and pH Tolerance, Isolated from Modern Freshwater Microbialites
Authors: White Richard Allen , Grassa Christopher J. , Suttle Curtis A. 
Published: August 2013

ABSTRACT

We report the draft genome sequence of
Exiguobacterium pavilionensis
strain RW-2, isolated from a cold thrombolytic microbialite. The isolate grows at temperatures from 4 to 50°C, at pH levels from 5 to 11, and in media without added NaCl or KCl or with 7% added NaCl.
The Draft Genome Sequence of Sphingomonas paucimobilis Strain HER1398 (
Proteobacteria
), Host to the Giant PAU Phage, Indicates That It Is a Member of the Genus
Sphingobacterium
(
Bacteroidetes
)
Authors: White Richard Allen , Suttle Curtis A. 
Published: August 2013

ABSTRACT

The draft genome sequence of
Sphingomonas paucimobilis
host index number (HER) 1398, host of the giant PAU phage isolated from silk moths (
Bombyx mori
), indicates that this isolate belongs within the genus
Sphingobacterium
. We suggest that
Sphingomonas paucimobilis
strain HER1398 be reclassified as
Sphingobacterium paucimobilis
strain HER1398.
Draft Genome Sequence of Lactococcus lactis subsp.
lactis
Strain YF11
Authors: Du Yuhui , Song Lifu , Feng Wenjing , Pei Guangsheng , Zheng Ping , Yu Zhichao , Sun Jibin , Qiao Jianjun 
Published: August 2013

ABSTRACT

Lactococcus lactis
subsp.
lactis
strain YF11 is a food preservative bacterium with a high capacity to produce nisin. Here, we announce the draft genome sequence of
Lactococcus lactis
subsp.
lactis
YF11 (2,527,433 bp with a G+C content of 34.81%).
Complete Genome Sequence of
Clostridium
sp. Strain DL-VIII, a Novel Solventogenic
Clostridium
Species Isolated from Anaerobic Sludge
Authors: Taghavi Safiyh , Izquierdo Javier A. , van der Lelie Daniel 
Published: August 2013

ABSTRACT

We report the genome sequence of
Clostridium
sp. strain DL-VIII, a novel Gram-positive, endospore-forming, solventogenic bacterium isolated from activated anaerobic sludge of a wastewater treatment plant. Aside from a complete
sol
operon, the 6,477,357-bp genome of DL-VIII reveals genes for several unique enzymes with applications in lignocellulose degradation, including two phenolic acid decarboxylases.
Whole-Genome Sequence of the Potentially Hypertransmissible Multidrug-Resistant Mycobacterium tuberculosis Beijing Strain OM-V02_005
Authors: Tateishi Yoshitaka , Tamaru Aki , Ogura Yoshitoshi , Niki Mamiko , Wada Takayuki , Yamamoto Taro , Hirata Kazuto , Hayashi Tetsuya , Matsumoto Sohkichi 
Published: August 2013

ABSTRACT

We report the draft genome sequence of
Mycobacterium tuberculosis
Beijing strain OM-V02_005, which exhibits possible hypertransmissible characteristics among the population of patients with multidrug-resistant tuberculosis in Osaka Prefecture, the largest urban area in western Japan.
Consent for the use of human biological samples for biomedical research: a mixed methods study exploring the UK public's preferences
Authors: Lewis Celine , Clotworthy Margaret , Hilton Shona , Magee Caroline , Robertson Mark J , Stubbins Lesley J , Corfield Julie 
Published: August 2013

ObjectiveA mixed-methods study exploring the UK general public's views towards consent for the use of biosamples for biomedical research.SettingCross-sectional population-based focus groups followed by an online survey.Participants12 focus groups (81 participants) selectively sampled to reflect a range of demographic groups; 1110 survey responders recruited through a stratified sampling method with quotas set on sex, age, geographical location, socioeconomic group and ethnicity.Main outcome measures(1) Views on the importance of consent when donating residual biosamples for medical research; (2) preferences for opt-in or opt-out consent approaches and (3) preferences for different consent models.ResultsParticipants believed obtaining consent for use of residual biosamples was important as it was ‘morally correct’ to ask, and enabled people to make an active choice and retain control over their biosamples. Survey responders preferred opt-in consent (55%); the strongest predictor was being from a low socioeconomic group (OR 2.22, 95% CI 1.41 to 3.57, p=0.001) and having a religious affiliation (OR 1.36, 95% CI 1.01 to 1.81, p=0.04). Focus group participants had a slight preference for opt-out consent because by using this approach more biosamples would be available and facilitate research. Concerning preferred models of consent for research use of biosamples, survey responders preferred specific consent with recontact for each study for which their biosamples are eligible. Focus group participants preferred generic consent as it provided ‘flexibility for researchers’ and reduced the likelihood that biosamples would be wasted. The strongest predictor for preferring specific consent was preferring opt-in consent (OR 4.58, 95% CI 3.30 to 6.35, p=0.015) followed by non-‘White’ ethnicity (OR 2.94, 95% CI 1.23 to 7.14, p<0.001).ConclusionsThere is a preference among the UK public for ongoing choice and control over donated biosamples; however, increased knowledge and opportunity for discussion is associated with acceptance of less restrictive consent models for some people.
Socioeconomic position and incidence of gastric cancer: a systematic review and meta-analysis
Authors: Uthman Olalekan A , Jadidi Elham , Moradi Tahereh 
Published: August 2013

BackgroundLow socioeconomic position (SEP) has been associated with increased risks of morbidity and mortality from many diseases. We investigated the associations between gastric cancer incidence and education, occupation and income as indicators for SEP.MethodsWe searched the PubMed and EMBASE databases for studies on SEP and gastric cancer incidence published from 1966 through February 2013. We used a random-effect model to pool the risk estimates from the individual studies. The relative indexes of inequality (RIIs) with their 95% CIs were used as summary estimates. We stratified the analysis by SEP indicators, sex, country's income group, geographical area, level of adjustment for an established risk factor, publication year, study design, type of control and length of follow-up.ResultsOf 1549 citations, 36 studies met our inclusion criteria. We observed an increased risk of gastric cancer among the lowest SEP categories in education (RII=2.97; 95% CI 1.923 to 4.58), occupation (RII=4.33; 95% CI 2.57 to 7.29) and combined SEP (RII=2.64; 95% CI 1.05 to 6.63) compared with the highest SEP categories. Although the association between the incidence of gastric cancer and the level of income is evident, it did not reach a statistically significant level (RII=1.25; 95% CI 0.93 to 1.68).ConclusionsWe found that the risk of gastric cancer incidence is higher among low SEP groups.
Patient needs from general practice following a traumatic injury: a qualitative study using narrative interviews with British service personnel
Authors: Bailey Thomas R 
Published: August 2013

ObjectivesTo explore the first period of sick leave in military patients following a traumatic battle injury, and the role of primary care. To identify if and where patients perceived difficulties.MethodParticipants were recruited from The Defence Medical Rehabilitation Centre (DMRC) Headley Court on their second admission. Purposive sampling was used to access a range of different injuries and experiences. Nine patients were interviewed at DMRC where they were asked to recount their stories throughout rehabilitation. Thematic and structural analysis of the narrative accounts was applied.ResultsThe majority of problems encountered by the participants occurred during their initial period of sick leave between Royal Centre for Defence Medicine (RCDM), Queen Elizabeth Hospital, Birmingham, and DMRC. Participants often had difficulty identifying who to contact if they had a problem on sick leave, with many ringing secondary care directly. Time spent travelling to medical reviews was identified as affecting the quality of leave.ConclusionsThere is a need for greater patient understanding regarding whom to contact should they develop problems while on sick leave. A patient passport containing all discharge documentation and simplified contact details may help reduce patient confusion regarding whom to contact. GPs require greater awareness and understanding of the complexity of these patients’ injuries and the need for early secondary care review to prevent delayed or inappropriate admissions. Most problems that patients face will occur on their first period of sick leave. Reducing the time spent on sick leave before admission to DMRC would limit the likelihood of problems occurring at this high-risk time.
Retraction
Authors: Vareille Marjolaine , Kieninger Elisabeth , Alves Marco P. , Kopf Brigitte S. , Möller Alexander , Geiser Thomas , Johnston Sebastian L. , Edwards Michael R. , Regamey Nicolas 
Published: August 2013

Vareille M, Kieninger E, Alves MP,et al. Impaired type I and type III interferon induction and rhinovirus control in human cystic fibrosis airway epithelial cells.Thorax2012;67:517-25. This article has been retracted.In our article recently published inThorax, we described a novel mechanism explaining the increased susceptibility of patients with cystic fibrosis (CF) to rhinovirus infections, namely defective interferon type I and III production by CF airway epithelial cells. In experiments performed after publication of the article we were unable to consistently replicate our findings of deficient interferon type I and III production by CF airway epithelial cells upon rhinovirus infection. In the light of these results, we carried out detailed investigations of the data reported in the above manuscript and regrettably found evidence of deliberate manipulation of experimental data by the first author Dr M. Vareille. This manipulation was accompanied in some instances by absence of original data files. The manipulation/original data absence involved data presented in most, if not all of the figures, thus we wish to fully retract the paper and apologise to the readers ofThoraxand to the scientific community for the inconvenience this has caused.We also checked data published by our group in manuscripts on which Dr Vareille was a co-author and found that data published in these manuscripts had not been manipulated. These two manuscripts, whose data and conclusions we stand by are:Edwards MR, Regamey N, Vareille M,et al.Impaired innate interferon induction in severe therapy resistant atopic asthmatic children.Mucosal Immunol2013;6:797–806. doi: 10.1038/mi.2012.118.andKieninger E, Vareille M, Kopf BS,et al. Lack of an exaggerated inflammatory response on virus infection in cystic fibrosis.Eur Respir J2012;39:297–304. doi: 10.1183/09031936.00054511.Dr. Vareille has received a letter from the Secretary General of the University of Bern condemning her scientific misconduct as a severe offence against the rules of scientific integrity. Her current employers have also been informed.All co-authors of the publication including Dr. Vareille concur with the retraction statement.
Constitutive β-Catenin Activation Induces Male-Specific Tumorigenesis in the Bladder Urothelium
Authors: Lin Congxing , Yin Yan , Stemler Kristina , Humphrey Peter , Kibel Adam S. , Mysorekar Indira U. , Ma Liang 
Published: August 2013

Abstract
The incidence for bladder urothelial carcinoma, a common malignancy of the urinary tract, is about three times higher in men than in women. Although this gender difference has been primarily attributed to differential exposures, it is likely that underlying biologic causes contribute to the gender inequality. In this study, we report a transgenic mouse bladder tumor model upon induction of constitutively activated β-catenin signaling in the adult urothelium. We showed that the histopathology of the tumors observed in our model closely resembled that of the human low-grade urothelial carcinoma. In addition, we provided evidence supporting the KRT5-positive;KRT7-negative (KRT5+; KRT7−) basal cells as the putative cells-of-origin for β-catenin–induced luminal tumor. Intriguingly, the tumorigenesis in this model showed a marked difference between opposite sexes; 40% of males developed macroscopically detectable luminal tumors in 12 weeks, whereas only 3% of females developed tumors. We investigated the mechanisms underlying this sexual dimorphism in pathogenesis and showed that nuclear translocation of the androgen receptor (AR) in the urothelial cells is a critical mechanism contributing to tumor development in male mice. Finally, we carried out global gene profiling experiments and defined the molecular signature for the β-catenin–induced tumorigenesis in males. Altogether, we have established a model for investigating sexual dimorphism in urothelial carcinoma development, and implicated synergy between β-catenin signaling and androgen/AR signaling in carcinogenesis of the basal urothelial cells. Cancer Res; 73(19); 5914–25. ©2013 AACR.