bluuebunny/crossref_metadata_2025_split huggingface dataset:
Red blood cells in Rett syndrome: oxidative stress, morphological changes and altered membrane organization
Authors: Ciccoli Lucia , De Felice Claudio , Leoncini Silvia , Signorini Cinzia , Cortelazzo Alessio , Zollo Gloria , Pecorelli Alessandra , Rossi Marcello , Hayek Joussef 
Published: May 2015

AbstractIn this review, we summarize the current evidence on the erythrocyte as a previously unrecognized target cell in Rett syndrome, a rare (1:10 000 females) and devastating neurodevelopmental disorder caused by loss-of-function mutations in a single gene (i.e.MeCP2,CDKL5, or rarelyFOXG1). In particular, we focus on morphological changes, membrane oxidative damage, altered membrane fatty acid profile, and aberrant skeletal organization in erythrocytes from patients with typical Rett syndrome andMeCP2gene mutations. The beneficial effects of ω-3 polyunsaturated fatty acids (PUFAs) are also summarized for this condition to be considered as a ‘model’ condition for autism spectrum disorders.
Approximate generalized derivations close to derivations in Lie C
*-algebras
Authors: Eshaghi Madjid , Abbaszadeh Sadegh 
Published: May 2015

Abstract
We apply a fixed point theorem to prove that there exists a unique
derivation close to an approximately generalized derivation in Lie
C
*-algebras. Also, we prove the hyperstability of generalized
derivations. In other words, we find some conditions under which an
approximately generalized derivation becomes a derivation.
Performance Analysis of Remote Desktop Virtualization based on Hyper-V versus Remote Desktop Services
Authors: Darabont Örs , Kiss Konrád József , Domokos József 
Published: May 2015

Abstract
The fast spread of computer networks and broadband Internet access, and also the development of different operating systems, makes possible to use different virtualization techniques and virtual machines. The release and spread of virtualization platforms makes possible the development of cost-effective information systems that can provide in addition dynamic resource management and simplified system administration.
In this paper we present a comparative performance analysis of Remote Desktop Virtualization based on Hyper-V versus Remote Desktop Services. We introduce system architecture for the two tested scenario and test environment including detailed hardware description.
The main conclusions of the paper are that despite the higher acquisition and maintenance costs, the Remote Desktop Services outperforms the Hyper-V based Remote Desktop Virtualization in memory, CPU and also storage management.
Hardware Implementation of a Neuro-Fuzzy Controller Using High Level Synthesis Tool
Authors: Tămas Tibor , Brassai Sándor Tihamér 
Published: May 2015

Abstract
The purpose of this work is to present the design flow and the implementation of a neuro-fuzzy controller Intellectual Property (IP) core, using High Level Synthesis (HLS) tool. The realized IP core is designed for FPGA based embedded system architectures. The implemented control algorithm is a Sugeno model based Adaptive Neuro-Fuzzy Inference System (ANFIS). The optimization possibilities using the HLS tool and the designing of the interfaces for the IP core are presented.
Kinematic Analysis of 2 DoF Spherical Mechanism Applying Constraint Equations
Authors: Tolvaly-Rosca Ferenc , Papp István 
Published: May 2015

Abstract
Constraint equations for complex robot structures can lead to a large number of equations. Also, constraint equations permits universal solutions for various mechanisms and solving a large number of equations can be simplified with numerical solutions. Therefore, if discreet solutions are allowed, a universal way to determine the necessary control parameters of a mechanism for different positions, or corresponding positions for different driving parameters is to use constraint equations. A direct kinematical analysis of a 2 DoF spherical mechanism with two driving axes is presented; a numerical simulation is made for given arm dimensions; according to specified degrees of freedom, a simplified CAD model is built and driven with the angular parameters.
Cataract surgery today and 20 years ago
Authors: Rozegnał-Madej Agnieszka , Żarnowski Tomasz 
Published: May 2015

Abstract
Introduction. Cataract surgery is one of the most important surgical procedures in ophthalmology.
Aim. The aim of this study is to compare cataract surgeries performed in 1994 and 2014.
Material and methods. A retrospective analysis of 100 cataract procedures in 1994, as well as a total of 100 cataract procedures performed in 2014. The authors considered the following factors: age, sex, vision acuity, cataract type, preoperative patient preparation, intra- and postoperative complications, and total hospitalization time.
Results. Back in 1994, extracapsular cataract extraction (ECCE) was the most common treatment technique. It caused more intraoperative complications (46) and postoperative complications (38) and longer total hospitalization time (9.25 days±3.25 SD). In 2014, all procedures were performed using phacoemulsification. As a result, the number of intraoperative (20) and postoperative (14) complications has dropped significantly. Total hospitalization time was also reduced (1.53 days±1.08 SD).
Conclusions. Phacoemulsification significantly improved cataract treatment. This method is much safer and more effective than ECCE.
Ovarian cancer: early detection, angiogenesis, lymphangiogenesis and current prospects for therapy
Authors: Wertel Iwona , Bednarek Wiesława , Czekierdowski Artur , Kotarski Jan 
Published: May 2015

Abstract
I Chair and Department of Gynecological Oncology and Gynecology is a specialist research center providing help in diagnostics and treatment of gynecological malignancies. The research work is focused on the processes of angiogenesis and lymphangiogenesis. Development of blood and lymphatic vessels is subject to research in a wide range of malignancies, including ovarian cancer, endometrial cancer and uterine sarcomas. Angiogenesis in malignancies of the female genital tract is investigated by using some modern 3D sonography that uses high-definition blood flow imaging. Ovarian Tumors and Early Ovarian Cancer Detection unit was established in 2002 and since that time more than 3500 patients with difficult to diagnose tumors have been consulted and treated in the Department. Ovarian cancer immunology studies are the second leading research fiekld in the 1st Chair Department of Gynecological Oncology and Gynecology. The Department is well equipped with diagnostic devices as well as a scientific laboratory. This allows for studies in the fields of imaging of masses, their immunology, biochemistry and molecular biology. Understanding immunological response in patients with ovarian cancer is the key to develop new, effective therapies, including immunological vaccines. In this area we are cooperating with prominent international research centers: Department of Surgery, University of Michigan and Department of Microbiology and Immunology, University of Arkansas. Results of our research are published in both Polish and international journals specializing in fields of gynecology, oncology, immunology and basic science.
Capillaroscopic patterns in patients with systemic sclerosis, psoriasis and alopecia and their correlations with serum concentrations of several angiogenic markers
Authors: Chodorowska Grażyna , Michalska-Jakubus Małgorzata , Bartosińska Joanna , Gerkowicz Agnieszka , Adamczyk Michał , Krasowska Dorota 
Published: May 2015

Abstract
Introduction. Capillaroscopy is a non-invasive imaging method that allows cutaneous microcirculation to be analyzed. During the last decades, a diagnostic and prognostic potential of nailfold capillaroscopy (NVC) has been gaining increasing appreciation. The main indications include Raynaud phenomenon and scleroderma spectrum diseases, however the usefulness of this technique is also suggested in a variety of non-rheumatic diseases.
Aim. To assess capillaroscopic patterns in systemic scleroderma (SSc), psoriasis (PV), psoriatic arthritis (PsA), alopecia areata (AA) and androgenetic alopecia. To evaluate serum levels of several endothelial and angiogenic markers, and their relation to capillaroscopic pattern.
Material and methods. There were evaluated 295 patients with systemic scleroderma (SSc), psoriasis (PV), psoriatic arthritis (PsA), alopecia areata (AA) and androgenetic alopecia, as well as age- and sex-matched controls, were examined. In each subject, NVC was performed and serum concentration levels of several angiogenic markers.
Results. In SSc three NVC patterns: early, active and late were distinguished. Angiopoietin-2 concentrations were higher and andothelial microparticles were lower in patients with late NVC pattern. We found several differences between the NVC pattern in PV and PsA. No correlations between NVC pattern and serum levels of angiogenic markers were revealed. In AA, we distinguished both normal and abnormal NVC patterns, although the normal patterns were more frequent. Branching capillaries and features of neoformation were often present in patients with the abnormal pattern. In androgenetic alopecia, the normal NVC pattern was most frequently present, however, we found several statistically significant capillarosopic alterations, like branching capillaries, features of neoformation and altered distribution of capillaries.
Discussion and Conclusions. Serum levels of Ang-2 and EMPs may reflect capillary damage in SSc. NVC pattern varies between PV and PsA patients. The presence of abnormal NVC patterns in alopecia patients might show the role of disturbances in microcirculation in the diseases. Further studies are required to confirm the hypothesis.
Czy istnieje „idealna” pozycja siedząca? / Does „ideal” sitting position exist?
Authors: Czaprowski Dariusz , Leszczewska Justyna , Sitarski Dominik 
Published: May 2015

Streszczenie
Wspołczesny człowiek większą cześć dnia spędza w pozycji siedzącej mimo, że sedenteryjny tryb życia często wymieniany jest jako jeden z determinantow zaburzeń postawy ciała oraz dolegliwości bolowych kręgosłupa. Negatywny wpływ długotrwałego przebywania w nieprawidłowej pozycji siedzącej powoduje, że w ramach postępowania profilaktycznego i leczniczego, fizjoterapeuci oraz lekarze często rekomendują rożne sposoby siedzenia w celu uniknięcia lub zmniejszenia dolegliwości bolowych kręgosłupa. Nie ma jednak jednolitych wytycznych odnośnie najbardziej pożądanej pozycji siedzącej, a jej charakterystyka jest przedmiotem dyskusji. Ze względu na negatywne konsekwencje pozycji siedzącej z kyfotycznym ustawieniem kręgosłupa (np. rozciąganie więzadeł nadkolcowych, wywołanie dolegliwości bolowych) w części rekomendacji sugeruje się konieczność odtwarzania w tej pozycji lordotycznego ustawienia odcinka lędźwiowego kręgosłupa. Wśrod zalet tej pozycji wymienia się m. in. mniejsze, w porownaniu do pozycji zgięciowej, ciśnienie w jądrze miażdzystym; mniejsze obciążenie kompresyjne w przedniej części pierścienia włoknistego oraz lepszą amortyzację wstrząsow w czasie ruchu. Pozycja ta może wiązać się jednak ze zwiększonym obciążeniem stawow międzywyrostkowych oraz zwiększoną aktywnością mięśni grzbietu i związanym z tym odczuciem dyskomfortu. Dlatego też w niektorych wytycznych rekomenduje się przyjmowanie pozycji siedzącej z umiarkowanym zgięciem części lędźwiowej kręgosłupa. Ma to zapewnić m. in. rownomierny rozkład obciążenia w krążkach międzykręgowych oraz mniejsze obciążenie stawow międzywyrostkowych.
Biorąc pod uwagę sprzeczne opinie w piśmiennictwie wydaje się, że nie istnieje jedna, uniwersalna, „idealna” pozycja siedząca. Dobor pozycji siedzącej powinien być zawsze indywidualny i uwzględniający osobniczą charakterystykę narządu ruchu. Szczegolnie, że każda pozycja (lordotyczna, kyfotyczna) utrzymywana przez dłuższy czas prowadzi do dyskomfortu oraz objawow ze strony tkanek okołokręgosłupowych.
Demograficzne uwarunkowania stosowania ćwiczeń fizycznych w profilaktyce bólu w chorobie dyskowej odcinka krzyżowo – lędźwiowego kręgosłupa / Demographic determinants of using exercise as the prophlaxis of the cross section of the disk – lumbar spine’s pain
Authors: Turkiewicz-Maligranda Agnieszka , Rymaszewska Joanna 
Published: May 2015

Streszczenie
Wstęp: Choroba dyskowa odcinka krzyżowo-lędźwiowego jest częstym schorzeniem, którego główną przyczyną jest degeneracja krążka międzykręgowego. Wiodącą dolegliwością jest ból w dolnym odcinku kręgosłupa oraz znaczne upośledzenie sprawności fizycznej. Jest to choroba chroniczna, z nawracającymi okresowo epizodami silnego bólu. Radzenie sobie z nią oznacza m.in. wzmacnianie mięśni okołokręgosłupowych poprzez regularne ćwiczenia fizyczne. Zakłada się, że czynniki socjodemograficzne będą miały związek z podjęciem zachowań zdrowotnych w postaci aktywności fizycznej dostosowanej do dyskopatii odcinka krzyżowo-lędźwiowego kręgosłupa. Celem przedstawionych badań była odpowiedź na pytanie czy zmienne demograficzne mają związek z podjęciem aktywności fizycznej dostosowanej do schorzenia dolnego odcinka kręgosłupa.
Materiał i metody: Badania miały charakter podłużny (dwa punkty pomiaru w odstępie pół roku), którym zostały objęte 92 osoby ze stwierdzoną rezonansem magnetycznym chorobą dyskową odcinka krzyżowo-lędźwiowego kręgosłupa. W badaniach wykorzystano: wywiad (dane socjodemograficzne), 11-punktową skalę VAS oraz ankietę dotyczącą podjętej aktywności fizycznej.
Wyniki: Badani przejawiali niski poziom aktywności fizycznej podejmowanej ze względu na schorzenie kręgosłupa (M=2,33 SD=2,21). Stwierdzono zależność pomiędzy młodszym wiekiem (H(2, N=92)=4,5, p<0,08) i wyższym wykształceniem (H(3, N=91)=16,62, p=0,001) a podejmowaniem aktywności fizycznej dostosowanej do schorzenia dolnego odcinka kręgosłupa.
Wnioski: Osoby badane w niewielkim stopniu podejmowały aktywność fizyczną ze względu na schorzenie kręgosłupa. Wiek oraz wykształcenie mają związek z podejmowaniem aktywności fizycznej dostosowanej do schorzenia dolnego odcinka kręgosłupa.
Klasyfikacja zawodników w lekkoatletycznych konkurencjach biegowych w świetle wyników uzyskanych na Igrzyskach Paraolimpijskich w latach 2000 – 2012 / Classification of athletes in athletics track events in terms of results obtained during Paralympics Games in years 2000 – 2012
Authors: Bednarczuk Grzegorz , Przepióra Wiktor , Rutkowska Izabela , Skowroński Waldemar 
Published: May 2015

Streszczenie
Wstęp: Zagadnienia związane z klasyfikacją w sporcie niepełnosprawnych to jeden z głównych obszarów badań w tym obszarze. Poszukuje się obiektywnych kryteriów oceny możliwości funkcjonalnych zawodników co ma umożliwić im sprawiedliwą rywalizację, w której wpływ na osiągany wynik ma przygotowanie do startu, a nie rodzaj i stopień niepełnosprawności.
Materiał i metody: Analiza wyników uzyskanych na Igrzyskach Paraolimpijskich (IP) w latach 2000-2012 miała na celu próbę oceny obowiązującego systemu klasyfikacji zawodników w lekkiej atletyce (LA) przez pryzmat uzyskiwanych przez nich wyników sportowych. Materiał badań stanowiły wyniki sportowe, na podstawie oficjalnych komunikatów z zawodów uzyskane przez zawodników z niepełnosprawnością narządu ruchu (NNR) w konkurencjach biegowych na IP w latach 2000-2012. Do określenia różnic wyników z IP pomiędzy klasami startowymi wykorzystano test U Manna-Whitney’a. Istotność statystyczną określono na poziomie p<0,05.
Wyniki: Największe zróżnicowanie wyników uzyskanych przez zawodników o zbliżonych możliwościach funkcjonalnych z NNR zaobserwowano wśród startujących na wózkach. Brak istotnych statystycznie różnic pomiędzy wynikami zawodników startujących w pozycji stojącej zaobserwowano w klasach T38 i T44 w biegu na 400m, w całym analizowanym okresie. Zbliżony poziom uzyskiwanych wyników zaobserwowano u kobiet z klas T53 i T54 uprawiających lekkoatletyczne konkurencje sprinterskie.
Wnioski: Specyfika dyscypliny jaką jest LA (duża liczba konkurencji o rożnym charakterze wysiłków) może powodować problemy w ocenie systemu klasyfikacyjnego, który nie uwzględnia konkurencji w której startują zawodnicy.
Clinical study regarding nasal reconstruction methods
Authors: Ionita Sabina , Lascar Ioan 
Published: May 2015

Abstract
BACKGROUND. In present days, there are described many reconstruction techniques for nasal post-traumatic and post-excision total defects, from simple suture to microsurgical free transfer in nasal reconstruction. It is important to follow the defect dimensions, its topography and also its etiology. The nasal aesthetic subunits principle is very important in aesthetic and functional reconstruction of a nasal defect.
MATERIAL AND METHODS. The clinical study from this paper was realised on the patients admitted in the Department of Plastic and Reconstructive Surgery of the Emergency Clinical Hospital from Bucharest, between 2012 and 2013. Different determinant factors were studied for the success of nasal reconstruction. It was compared the difference between the reconstruction of the whole nasal subunit, based on aesthetic subunits principle, and the reconstruction of the defect.
RESULTS. Although in our clinic the reconstruction of the defect is used in the majority of the cases and rarely the reconstruction based on aesthetic subunits principle, very good results were obtained, with a reduced number of complication and very few relapses.
CONCLUSION. The success of the reconstruction depends on multiple factors regarding the type of the defect. The grafts can give very good results in all aesthetic subunits, while the nasogenian flap has good results for the reconstruction of the nasal wing and lobule defects. The frontal flap is the first option for reconstruction of the dorsum nasi with satisfactory results. This paper is supported by the Sectoral Operational Programme Human Resources Development (SOP HRD), financed from the European Social Fund and by the Romanian Government under the contract number POSDRU/159/1.5/137390
Specific features of endoscopic dacryocystorhinostomy – case report
Authors: Lapusneanu Lucian , Neacsu Alina , Naca Andreea 
Published: May 2015

Abstract
OBJECTIVE. The aim of the study was to evaluate the endoscopic dacryocystorhinostomy (DCR) with some particularities and its advantages over external DCR.
MATERIAL AND METHODS. We evaluated 3 female patients (age range 35-84 years) diagnosed with chronic dacryocystitis - lacrimal sac abscess (2 cases) and lacrimal sac fistula (1 case). All patients presented a history of repeated episodes of acute dacryocystitis initially treated with broad spectrum antibiotics by the ophthalmologist. The evaluation protocol consisted in cranio-facial CT scan or MRI for the evaluation of the lacrimal sac and nasal structures, an ophthalmologic examination with the catheterization of the superior and inferior lacrimal punctum with a light probe to verify the permeability of the lacrimal pathway, and the Jones test with fluorescein to receive information about the common lacrimal path. Lacrimal syringing with regurgitation of fluid from the opposite punctum was the only criteria to decide the surgery. In all three cases we performed an endoscopic DCR, with stent insertion in two cases and a laco-dacryo-rhinostomy in one case. In only one case a reintervention was needed 12 months later.
CONCLUSION. The endoscopic DCR, with its different particularities, is a safe surgical procedure with a low rate of complications, being the treatment of choice for the treatment of nasolacrimal duct obstruction.
The Relationship of Kicking Ball Velocity with Anthropometric and Physiological Factors in Soccer
Authors: Bekris Evangelos , Gioldasis Aristotelis , Bekris Vasilis , Gissis Ioannis , Komsis Stergios , Mitrousis Ioannis 
Published: May 2015

Abstract
The purpose of the current study was to examine the relationship of kicking ball velocity with anthropometric and physiological parameters in soccer. Specifically, the researchers examined how the anthropometric variables such as body weight, body fat, body mass index, and body height, as well as the physiological variables such as running speed, lower body explosive strength, lower limb endurance, balance, and agility are related to ball velocity. Fifty eight U-12 male soccer players, sixty one U-14, forty three U-16, and thirty five adult male soccer players participated in this study. The results showed that ball velocity is related to both anthropometric and physiological factors differently according to the age of the players. It was also confirmed that ball velocity is an indicator of playing level. The key finding from this research was that ball velocity is related to the explosive strength parameters. Thus this relationship is an indicator that coaches and trainers have to take into account so as maximize the kicking potential of their players.
Clement of Alexandria’s Anti-Valentinian Interpretation of Gen 1:26−27
Authors: Edwards Robert G. T. 
Published: May 2015

Abstract
Clement of Alexandria’s interpretations of Gen 1:26−27 are made in reaction to what he perceived to be heretical Valentinian interpretations of the same passage. Clement’s notes on Valentinian biblical interpretation, the Excerpta ex Theodoto, contain the content against which he is reacting, which he perceives to be heretical in terms of their determinism: people made according to the “image” and the “likeness” of God consist of two different classes of people, non- Christians and ecclesial Christians respectively. On top of this the Valentinians add one more category of humanity which is according to “its own” nature-this is the category to which the gnostic Christians, the Valentinians, belong. Clement counters this perceived determinism by having “image” and “likeness” correspond to two stages of the Christian life: “faith” (πίστις) and “knowledge” (γνῶσις) respectively. By doing this, he appropriates this aspect of Valentinian theology into his own orthodox-that is, apostolic and ecclesiastical-Christian theological and philosophical project.
Basil of Caesarea’s Uses of Origen in His Polemic against Astrology
Authors: Rasmussen Adam D. P. 
Published: May 2015

Abstract
Basil of Caesarea, in his polemic against astrology (Homiliae in hexaemeron 6,5−7), makes direct, creative uses of Origen’s anti-astrological treatise (Philocalia 23). My argument is based on an identical context, namely the interpretation of Gen 1:14b, and five close similarities in content, some verbatim, between Basil’s sermon and Origen’s anti-astrological polemic (and in one case a passage from De principiis). These five similarities are on the topics of the definition of genethlialogy, the system of genethlialogy, aspects, the life of the stars, and fatalism. In each instance, Basil uses Origen in a different way. These uses run the gamut from the wholesale adoption of Origen’s definition of genethlialogy to the refutation of Origen’s belief that the stars are alive. Adaptation is necessitated, not only by Basil’s inherent creativity and relative independence from Origen, but by the fact that the rhetorical form of Basil’s treatment is different from Origen’s: whereas Origen offers a commentarial treatment with a systematic question-and-answer structure, Basil’s argument is a rhetorically sophisticated diatribe, which uses sarcasm and mockery to entertain as well as persuade its audience. Basil uses Origen sometimes freely, sometimes verbatim, but always critically, to support his own goals.