bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gonadotropin-Releasing Hormone Stimulates the Biosynthesis of Pregnenolone Sulfate and Dehydroepiandrosterone Sulfate in the Hypothalamus
Authors: Burel Delphine , Li Jian Hua , Do-Rego Jean-Luc , Wang Ai Fen , Luu-The Van , Pelletier Georges , Tillet Yves , Taragnat Catherine , Kwon Hyuk Bang , Seong Jae Young , Vaudry Hubert 
Published: April 2013

AbstractThe sulfated neurosteroids pregnenolone sulfate (Δ5PS) and dehydroepiandrosterone sulfate (DHEAS) are known to play a role in the control of reproductive behavior. In the frog Pelophylax ridibundus, the enzyme hydroxysteroid sulfotransferase (HST), responsible for the biosynthesis of Δ5PS and DHEAS, is expressed in the magnocellular nucleus and the anterior preoptic area, two hypothalamic regions that are richly innervated by GnRH1-containing fibers. This observation suggests that GnRH1 may regulate the formation of sulfated neurosteroids to control sexual activity. Double labeling of frog brain slices with HST and GnRH1 antibodies revealed that GnRH1-immunoreactive fibers are located in close vicinity of HST-positive neurons. The cDNAs encoding 3 GnRH receptors (designated riGnRHR-1, -2, and -3) were cloned from the frog brain. RT-PCR analyses revealed that riGnRHR-1 is strongly expressed in the hypothalamus and the pituitary whereas riGnRHR-2 and -3 are primarily expressed in the brain. In situ hybridization histochemistry indicated that GnRHR-1 and GnRHR-3 mRNAs are particularly abundant in preoptic area and magnocellular nucleus whereas the concentration of GnRHR-2 mRNA in these 2 nuclei is much lower. Pulse-chase experiments using tritiated Δ5P and DHEA as steroid precursors, and 3′-phosphoadenosine 5′-phosphosulfate as a sulfonate moiety donor, showed that GnRH1 stimulates, in a dose-dependent manner, the biosynthesis of Δ5PS and DHEAS in frog diencephalic explants. Because Δ5PS and DHEAS, like GnRH, stimulate sexual activity, our data strongly suggest that some of the behavioral effects of GnRH could be mediated via the modulation of sulfated neurosteroid production.
Hard-templating Synthesis of Mesoporous Pt-Based Alloy Particles with Low Ni and Co Contents
Authors: Karthika Prasannan , Ataee-Esfahani Hamed , Deng Yu-Heng , Wu Kevin C-W , Rajalakshmi Natarajan , Dhathathreyan Kaveripatnam S , Arivuoli Dakshinamoorthy , Ariga Katsuhiko , Yamauchi Yusuke 
Published: April 2013

Abstract
Pt-Based mesoporous bimetallic alloy particles with low Co and Ni contents were synthesized successfully through a hard-templating method and show great potential as effective catalysts for methanol oxidation reactions.
Taxonomic research priorities for the conservation of the South African flora
Authors: Von Staden Lize , Raimondo Domitilla , Dayaram Anisha 
Published: April 2013

Taxonomic revisions, monographs and floras are the most important, and often the only source of data for assessing the extinction risk of plants, with recent revisions contributing to more accurate assessments. The recently completed Red List of South African plants involved an overview of the taxonomic literature pertaining to the South African flora, providing an opportunity to identify critical gaps in taxonomic coverage. In this study we identified taxonomic research priorities for effective conservation of South African plants. Priorities were identified at genus level, according to time since last revision, level of endemism, collecting effort, proportion of taxa included in revisions, and specimen identification confidence. Although the results indicate that 62% of the flora has been recently revised, revisionary taxonomic output has declined drastically, particularly in the past 10 years. This decline is a result of a decrease in revisionary productivity per taxonomist and not a result of a decline in the number of working taxonomists. The family Aizoaceae is the top priority for taxonomic research with 55% of taxa in need of revision, followed by Hyacinthaceae with 34% of taxa not yet revised. Ericaceae, Euphorbiaceae, Rutaceae, Malvaceae, Asteraceae and Acanthaceae are also priorities with over 30% of taxa last revised before 1970. We recommend the reinstatement of the Flora of Southern Africa project in an online format in order to centralise South Africa’s existing taxonomic information and reinvigorate revisionary taxonomic study. This project will allow South Africa to fulfil its commitments to the Convention on Biodiversity by achieving Target 1 of the Global Strategy for Plant Conservation.
Coping Strategies for Child Bully-Victims
Authors: Buxton David , Potter Mona Patel , Bostic Jeff Q. 
Published: April 2013

CME Educational Objectives

1.
Distinguish what types of bullying are most common at different ages.

2.
Describe six questions to screen for bullying and its effects.

3.
Identify three interventions for students and parents to address bullying, victimization, bystanding, and system rules that allow bullying.

Bullying affects most children in some way, as victims, bystanders, or bullies, during childhood. Children exposed to bullying may present with physical as well as psychological symptoms, and experience negative effects lasting into adulthood. This article provides information regarding bullying screening and interventions with pediatric and adolescent patients. Taking into account a child’s developmental stage, age-appropriate tactics are provided to address bullying, victimization, bystanding, and system “rules” that tolerate or foster bullying.
Female Athletic Training Students' Perceptions of Motherhood and Retention in Athletic Training
Authors: Mazerolle Stephanie M. , Gavin Kerri 
Published: April 2013

Context:
Motherhood appears to be a catalyst in job turnover for female athletic trainers, especially those employed at the National Collegiate Athletic Association Division I level. However, most researchers examining this topic have investigated the perspectives of those who are currently employed rather than those who are preparing to enter the profession.

Objective:
To evaluate female athletic training students' perceptions of motherhood and retention.

Design:
Qualitative study.

Setting:
Athletic training education program.

Patients or Other Participants:
A total of 18 female athletic training students volunteered to participate. They were enrolled in 1 Commission on Accrediting Athletic Training Education–accredited athletic training program and represented 3 levels of academic study.

Data Collection and Analysis:
The participants responded to a series of questions related to work–life balance and retention in athletic training. Analysis of the data followed a general inductive process. Credibility was established by interpretive member checks and peer review.

Results:
The first theme, clinical setting, speaks to the belief that work–life balance and retention in athletic training require an employment setting that fosters a family-friendly atmosphere and a work schedule (including travel) that allows for time at home. The second theme, mentorship, reflects the acknowledgment that a female mentor who is successful in balancing the roles of mother and athletic trainer can serve as a role model. The final theme, work–life balance strategies, illustrates the need to have a plan in place to meet the demands of both home and work life.

Conclusions:
A female athletic trainer who is successfully balancing her career and family responsibilities may be the most helpful factor in retention, especially for female athletic training students. Young professionals need to be educated on the importance of developing successful work–life balance strategies, which can be helpful in reducing attrition from the profession.
Lionel Groulx devant la France catholique: contacts, échanges et collaboration
Authors: Bock Michel 
Published: April 2013

L’étude de la construction du réseau français de Lionel Groulx permet de jeter un éclairage probant sur les moyens par lesquels on a tenté, au sein de l’élite canadienne-française, de bâtir des ponts avec l’Hexagone au début du XXe siècle. C’était vers les milieux associés à la « renaissance littéraire catholique » des années 1910 et 1920 que gravitait tout naturellement l’abbé Groulx, que séduisait le combat des catholiques militants contre la « décadence » engendrée par la modernité philosophique et pour la restauration morale et spirituelle du « génie » français, un combat qui pouvait englober celui des maurrassiens, du moins avant la condamnation pontificale de 1926, mais qui le débordait largement. Sensible aux divergences qui caractérisaient les milieux catholiques de France, Groulx entretenait très peu de liens avec le « noyau dur » du mouvement maurrassien et préférait s’associer à des militants et à des intellectuels dont le rapport au religieux ne souffrait d’aucune ambiguïté, d’une part, et qui, d’autre part, s’intéressaient de plus près aux affaires canadiennes-françaises.
Service social : une longue tradition d’intervention lors d’une crise suicidaire
Authors: Tremblay Gilles 
Published: April 2013

Ce texte porte sur la place du service social dans la recherche et l’intervention en matière de suicide. Il se divise en trois sections : le paradoxe du service social par rapport au suicide, les apports de cette profession dans l’intervention et la recherche, et un exemple à partir d’une recherche menée par l’auteur sur la dépression chez les hommes.
The prevalence of violence towards the elderly: a critical review of the literature
Authors: Santos Ana João , Nicolau Rita , Fernandes Ana Alexandre , Gil Ana Paula 
Published: April 2013

The studies on the prevalence of violence towards the elderly in a family context that have been conducted in the last thirty years, especially in Europe and Anglo-Saxon countries, are not sufficiently elucidative. This is due to shortcomings in both the definition of their theoretical models and their operative concepts. The authors of this article have systematically reviewed the literature and identified a diversity of definitions and research designs, which has an inevitable impact in terms of varying estimates. The European public perception of this problem is also at odds with the low figures contained in this type of estimate. The authors offer somethoughts about the underlying reasons for these representations, and critique the estimates made in population-based prevalence studies.
Origin of Species
Authors: Sorkin Michael 
Published: April 2013

AbstractThe renowned architect, academic and thinker Michael Sorkin reflects on the geneses of architecture, where it comes from and its current status, concluding that ‘the idea of an architecture that participates in a collective stewardship and equitable sharing of the earth ‐ and wears it on its sleeve ‐ works for me’. He illustrates his article with some of his studio's work from the last two decades that has been inspired by nature in its iconography, embracing an entire menagerie of forms.
Quit the Grey Limbo and Return to Paradise
Authors: Cannon Matthew , Gianvanni Mascia 
Published: April 2013

AbstractIn three projects, Matthew Cannon and Mascia Gianvanni of FutureScape Studio explore the possibilities of alleviating the mundaneness of urban life through the introduction of the absurdity of nature, which brings ‘joy and laughter to the stressed worker’. Devices range from a sardine on the London Underground and a giraffe in the office to injecting a sublime, painterly light into the city.
Landscape Utopianism: Information, Ecology and Generative Pastoralism
Authors: Marinic Gregory 
Published: April 2013

AbstractArchitect and educator Gregory Marinic describes how the 21st century is witnessing the rise of a new utopianism through landscape/architectural interventions that pursue the possibilities of ‘ersatz utopias within our quotidian world’. He illustrates this with his own collaborative works and competition entries for d3, an art‐architecture stewardship programme based in New York of which he is director.
Open Fields: The New Rural Design Revolution
Authors: Parvin Alastair 
Published: April 2013

AbstractAlastair Parvin, an architectural and strategic designer at 00:/, calls for a focus on ‘the opposite side of the urbanisation story: the impact that urbanisation has on rural areas’. He advocates a rural design revolution that re‐engages with farming and the countryside as a site of intense production, rather than as a preserve for nostalgia and leisure activities.
Et in Arcadia ego, Et in Arcadia est
Authors: Rhowbotham Kevin 
Published: April 2013

AbstractArchitect, academic and broadcaster Kevin Rhowbotham scrutinises the reasoning and value of the New Pastoralism project. He dispels the Arcadian impulse as ‘a specious and mythicised image of the rural’, calling upon architects to seek a true understanding of rural conditions in relation to the urban.
A Multiwalled‐Carbon‐Nanotube‐Based Biosensor for Monitoring Microcystin‐LR in Sources of Drinking Water Supplies
Authors: Han Changseok , Doepke Amos , Cho Wondong , Likodimos Vlassis , de la Cruz Armah A. , Back Tyson , Heineman William R. , Halsall H. Brian , Shanov Vesselin N. , Schulz Mark J. , Falaras Polycarpos , Dionysiou Dionysios D. 
Published: April 2013

AbstractA multiwalled carbon nanotube (MWCNT)‐based electrochemical biosensor is developed for monitoring microcystin‐LR (MC‐LR), a toxic cyanobacterial toxin, in sources of drinking water supplies. The biosensor electrodes are fabricated using vertically well‐aligned, dense, millimeter‐long MWCNT arrays with a narrow size distribution, grown on patterned Si substrates by water‐assisted chemical vapor deposition. High temperature thermal treatment (2500 °C) in an Ar atmosphere is used to enhance the crystallinity of the pristine materials, followed by electrochemical functionalization in alkaline solution to produce oxygen‐containing functional groups on the MWCNT surface, thus providing the anchoring sites for linking molecules that allow the immobilization of MC‐LR onto the MWCNT array electrodes. Addition of the monoclonal antibodies specific to MC‐LR in the incubation solutions offers the required sensor specificity for toxin detection. The performance of the MWCNT array biosensor is evaluated using micro‐Raman spectroscopy, including polarized Raman measurements, X‐ray photoelectron spectroscopy, cyclic voltammetry, optical microscopy, and Faradaic electrochemical impedance spectroscopy. A linear dependence of the electron‐transfer resistance on the MC‐LR concentration is observed in the range of 0.05 to 20 μg L−1, which enables cyanotoxin monitoring well below the World Health Organization (WHO) provisional concentration limit of 1 μg L−1 for MC‐LR in drinking water.
Nano‐Sized CT Contrast Agents
Authors: Lee Nohyun , Choi Seung Hong , Hyeon Taeghwan 
Published: April 2013

AbstractComputed tomography (CT) is one of the most widely used clinical imaging modalities. In order to increase the sensitivity of CT, small iodinated compounds are used as injectable contrast agents. However, the iodinated contrast agents are excreted through the kidney and have short circulation times. This rapid renal clearance not only restricts in vivo applications that require long circulation times but also sometimes induces serious adverse effects related to the excretion pathway. In addition, the X‐ray attenuation of iodine is not efficient for clinical CT that uses high‐energy X‐ray. Due to these limitations, nano‐sized iodinated CT contrast agents have been developed that can increase the circulation time and decrease the adverse effects. In addition to iodine, nanoparticles based on heavy atoms such as gold, lanthanides, and tantalum are used as more efficient CT contrast agents. In this review, we summarize the recent progresses made in nano‐sized CT contrast agents.
Characterization of human cortical gene expression in relation to glucose utilization
Authors: Sterner Kirstin N. , Mcgowen Michael R. , Chugani Harry T. , Tarca Adi L. , Sherwood Chet C. , Hof Patrick R. , Kuzawa Christopher W. , Boddy Amy M. , Raaum Ryan L. , Weckle Amy , Lipovich Leonard , Grossman Lawrence I. , Uddin Monica , Goodman Morris , Wildman Derek E. 
Published: April 2013

ObjectivesHuman brain development follows a unique pattern characterized by a prolonged period of postnatal growth and reorganization, and a postnatal peak in glucose utilization. The molecular processes underlying these developmental changes are poorly characterized. The objectives of this study were to determine developmental trajectories of gene expression and to examine the evolutionary history of genes differentially expressed as a function of age.MethodsWe used microarrays to determine age‐related patterns of mRNA expression in human cerebral cortical samples ranging from infancy to adulthood. In contrast to previous developmental gene expression studies of human neocortex that relied on postmortem tissue, we measured mRNA expression from the nondiseased margins of surgically resected tissue. We used regression models designed to identify transcripts that followed significant linear or curvilinear functions of age and used population genetics techniques to examine the evolution of these genes.ResultsWe identified 40 transcripts with significant age‐related trajectories in expression. Ten genes have documented roles in nervous system development and energy metabolism, others are novel candidates in brain development. Sixteen transcripts showed similar patterns of expression, characterized by decreasing expression during childhood. Comparative genomic analyses revealed that the regulatory regions of three genes have evidence of adaptive evolution in recent human evolution.ConclusionsThese findings provide evidence that a subset of genes expressed in the human cerebral cortex broadly mirror developmental patterns of cortical glucose consumption. Whether there is a causal relationship between gene expression and glucose utilization remains to be determined. Am. J. Hum. Biol. 25:418–430, 2013. © 2013 Wiley Periodicals, Inc.
Methodik zur Unsicherheitsbewertung und Sensitivitätsanalyse für thermische Gebäudesimulationen
Authors: Burhenne Sebastian , Herkel Sebastian 
Published: April 2013

AbstractUnsichere Randbedingungen haben einen großen Einfluss auf das Ergebnis von Gebäudesimulationen. Trotzdem werden Unsicherheitsbewertungen und Sensitivitätsanalysen bisher in der Planungspraxis und auch in wissenschaftlichen Untersuchungen selten durchgeführt. In diesem Beitrag wird eine Methodik zur Unsicherheitsbewertung und Sensitivitätsanalyse für thermische Gebäudesimulationen vorgestellt. Diese wird exemplarisch angewendet, um Einsatzmöglichkeiten darzustellen. Potentielle Einsatzgebiete sind Simulationen im Planungsprozess von Gebäuden sowie eine simulationsbasierte Gebäudebetriebsanalyse. Die Anwendung der Methodik kann dazu beitragen, den Planungsprozess und den Gebäudebetrieb zu verbessern.Methodology for uncertainty and sensitivity analysis for building performance simulation. Uncertainties in simulation input have a big influence on building performance simulation results. Nevertheless, uncertainty quantification and sensitivity analysis is not commonly applied in the design practice and also in scientific research. In this paper a methodology for uncertainty quantification and sensitivity analysis is introduced. The methodology is applied to an example case to illustrate possible applications. It can be used within the design stage of buildings as well as for simulation ‐based building operation analysis. The methodology can improve the design process as well as building operation.
Conveying Characteristics of Pulverized Coal in a Top‐Discharge Blow Tank System
Authors: Xu G.‐L. , Chen X.‐P. , Liang C. , Liu D.‐Y. , Xu P. , Cai J.‐Y. , Zhao C.‐S. 
Published: April 2013

AbstractBased on the experiments of pulverized coal pneumatic conveying using nitrogen as carrier, the influences of riser inlet height above the gas distribution plate, riser diameter, pulverized coal external moisture content, and supplemental gas flow rate on the conveying characteristics such as pulverized coal mass flow rate and solid‐gas ratio were investigated in a laboratory‐scale experimental setup of a top‐discharge blow tank under atmospheric pressure. There exists an optimal riser inlet height for a given top‐discharge blow tank. The supplemental gas is one of the critical factors affecting the conveying stability and continuity. A model for material mass flow rate prediction with errors ranging from –25 % to +15 % is presented.
Development of a Scalable Method for Manufacturing High‐Temperature CO2 Capture Sorbents
Authors: Yu C. T. , Chen W. C. 
Published: April 2013

AbstractAn engineered process for scalable manufacture of a calcium aluminum carbonate CO2 sorbent with production amounts of about 1000 g per hour has been developed. The process includes mixing and heating, solid‐liquid separation, drying and extrusion, crushing and conveying, and calcined molding steps. The sorbent preparation involves the coprecipitation of Ca2+, Al3+, and CO32– under alkaline conditions. By adjusting the Ca:Al molar ratio, a series of Ca‐rich materials could be synthesized for use as CO2 sorbents at 750 °C. A calcium acetate‐derived sorbent exhibited better cyclic stability than sorbents originating from CaCl2 and Ca(NO3)2. The initial sorption capacity increased with CaO concentration. High stability of more than 90 % was maintained by the Ca:Al sorbents after 40 looping tests.
Amide‐Controlled Highly Selective Catalytic Borylcupration of Allenes
Authors: Yuan Weiming , Zhang Xue , Yu Yihua , Ma Shengming 
Published: April 2013

AbstractA novel copper‐catalyzed, highly regio‐ and stereoselective borylcupration of substituted 2,3‐allenamides with bis(pinacolato)diboron producing Z‐β‐borylated β,γ‐unsaturated enoamides has been demonstrated. Due to the unique effect of the amide‐group, perfect regio‐ and stereoselectivity and good to excellent yields have been achieved, which were rationalized by a DFT study.
ChemInform Abstract: The New Alkali Cyclotrisilicate Cs8[Si6O16].
Authors: Hlukhyy Viktor , Faessler Thomas F. 
Published: April 2013

AbstractHygroscopic transparent single crystals of Cs8[Si6O16] are obtained by high‐temperature reaction of Cs, Si, WO3, and HgO in the molar ratio of 5:5:1:1 (sealed Nb crucible in a fused silica tube, 1.
ChemInform Abstract: Sulfide Iodides (MSI) of the Heavier Lanthanoids (M: Gd—Lu): Crystal Structures and Magnetic Properties.
Authors: Blaschkowski Bjoern , Rosner Helge , Schnelle Walter , Schleid Thomas 
Published: April 2013

AbstractLanthanoide sulfide iodides LnSI with Ln: Gd—Lu are prepared by solid state reaction of an equimolar mixture of Ln, S and I (fused silica tube, 900 °C, 10 d) and powder XRD cell parameters are given.
ChemInform Abstract: Ternary Aluminides Ln0.67Ni2Al6 (Ln: Sc, Y, Gd—Lu) with Partly Disordered Structures.
Authors: Matselko Oksana , Pukas Svitlana , Lutsyshyn Yuriy , Gladyshevskii Roman , Kaczorowski Dariusz 
Published: April 2013

AbstractThe title compounds are prepared by arc‐melting of the elements followed by annealing under vacuum at 600 °C for one month.
ChemInform Abstract: High Pressure Synthesis and Crystal Structure of a Ternary Superconductor Ca2Al3Si4 Containing Layer Structured Calcium Sub‐Network Isomorphous with Black Phosphorus.
Authors: Tanaka Masashi , Zhang Shuai , Tanaka Yuki , Inumaru Kei , Yamanaka Shoji 
Published: April 2013

AbstractThe title compound is prepared by reaction of a stoichiometric mixture of CaSi2, Al, and Si at 1000 °C under a pressure of 5 GPa (1 h).
ChemInform Abstract: Tandem Sequence of Phenol Oxidation and Intramolecular Addition as a Method in Building Heterocycles.
Authors: Ratnikov Maxim O. , Farkas Linda E. , Doyle Michael P. 
Published: April 2013

AbstractRhodium‐catalyzed oxidation of p‐substituted phenols with tBuOOH followed by intramolecular Michael‐addition opens access to a variety of oxa‐ and aza‐heterocycles.