bluuebunny/crossref_metadata_2025_split huggingface dataset:
Modified Ross score and echocardiographic score in children with heart failure: a subgroup analysis
Authors: Setiyawan I Made Karma , Kartika Yantie Ni Putu Veny , Widnyana Anak Agung Ngurah Ketut Putra , Sidiartha I Gusti Lanang , Karyana Putu Gede , Arimbawa I Made 
Published: July 2024

Background Over the past two decades, heart failure in children has increased in terms of symptom recognition and prevalence. The initial clinical manifestations of heart failure in children are non-specific. Therefore, diagnosis requires the support of echocardiography. The symptomatic severity of heart failure in children can be classified through a simple scoring system such as Ross score. The duration of heart disease, duration of therapy, and cardiac remodeling status may have clinical and anatomical effects on the disease.
Objective To analyze for a possible correlation between modified Ross score and echocardiographic score by subgroup analysis consisting of duration of heart disease, duration of therapy, and cardiac remodeling.
Methods This cross-sectional study included children aged 1 month - 18 years with heart failure who sought treatment at Prof.Dr. I.G.N.G Ngoerah Hospital, Denpasar from June 2019 to February 2020. Cardiac remodeling was defined as >20% increase in left ventricle internal end diastolic dimension (LVIDd) compared to normal values, ??based on body surface area. Spearman’s correlation test was used for statistical analysis.
Results A total of 30 subjects were analyzed in this study. The median modified Ross score and echocardiography score were 3 points (range 2-11) and 4 (range 2-6), respectively. The median durations of heart disease and preventive heart failure therapy were 2 years (range 7 days-15 years) and 1 year (range 7 days-15 years), respectively. The mean LVIDd was 4.3 (SD 1.4) cm. Twenty-one out of 30 subjects experienced a ? 20% increase of LVIDd from baseline. The modified Ross score and echocardiographic score had no significant correlation (r=0.18; P=0.33). However, the modified Ross score had significant correlations with duration of heart disease (r=-0.632; P<0.001) as well as duration of therapy (r=-0.584; P=0.001). In addition, no correlation was found between echocardiographic score with heart disease and therapy duration (P>0.05). Echocardiography score and remodelling process was significantly correlated (r=0.64; P<0.001).
Conclusion There is no correlation between modified Ross score and echocardiographic score. Duration of heart disease and duration of therapy are significantly negatively correlated with modified Ross scores. The remodelling process is positively correlated with echocardiographic score. Further research on acute symptomatic and validated echocardiographic scores are needed.
Efficacy of lactose-free formula in acute diarrheal management for children under 5 years: a systematic review and meta-analysis
Authors: Putri Ayu Maghfira Nida , Witarto Andro Pramana , Yofi Fadhil Abiyyu , Suasti Ni Made Adnya , Alawiyah Kania 
Published: July 2024

Background Acute diarrhea is the most common gastrointestinal disease in children under five years of age with high morbidity and mortality risk. The use of lactose-free formula in the management of children with acute diarrhea was said to accelerate the diarrheal resolution time.
Objective To determine the efficacy of lactose-free formula in managing acute diarrhea in pediatric patients by systematic review and meta-analysis.
Methods A comprehensive literature search was conducted on PubMed, Proquest, Web of Science, and CINAHL Plus Database from November 1971 to July 11th, 2021. The study selection process was carried out under PRISMA 2020 guidelines based on several eligibility criteria. The quality of the included studies were further assessed using Modified Jadad Scores.
Results Fifteen randomized controlled trials (RCTs) were included, involving a total of 1,390 children with acute diarrhea. Shorter recovery time (MD -0.21; 95%CI -0.50 to 0.08; P=0.16) was observed in patients receiving lactose-free formula than the control group. However, this finding was not statistically significant. The subgroup analysis showed that lactose-free formula significantly shortened the recovery time compared to oral rehydration solution (ORS) group (MD -0.70; 95%CI -0.98 to -0.41; P=0.00001). Furthermore, lactose-free formula also significantly reduced the amount of stool output (MD -0.61; 95%CI -0.86 to -0.36; P=0.00001) and the incidence of persistent diarrhea more than seven days (OR 0.22; 95%CI 0.10 to 0.51; P=0.0004) compared to the control group.
Conclusion Lactose-free formula as dietary management for acute diarrhea in children can reduce stool output and the incidence of persistent diarrhea for more than seven days. It also may shorten the recovery time compared to the administration of ORS alone.
Evaluation of performance of Indonesian Sepsis National Guidelines (PNPK) 2021 in diagnosing pediatric bacterial sepsis
Authors: Asiyani Lilis Siti , Rusmawatiningtyas Desy , Indrawanti Ratni Indrawanti , Arguni Eggi Arguni , Wibowo Tunjung Wibowo , Nurnaningsih Nurnaningsih Nurnaningsih 
Published: July 2024

Background Sepsis remains one of the causes of child morbidity and mortality worldwide. The reference standard diagnosis of sepsis is blood culture, but its false negative is relatively high. Therefore, a validated triage tool is needed for rapid
diagnosis. In Indonesia, diagnosis and management of pediatric sepsis are based on Indonesian Sepsis National Guidelines 2021.
Objective To evaluate the performance of Indonesian Sepsis National Guidelines 2021 in diagnosing pediatric bacterial sepsis in PICU.
Methods This cross-sectional study was conducted in the PICU unit of Dr. Sardjito Hospital, Yogyakarta, using subject’s the medical records. All patients with suspected bacterial infection who were admitted to the PICU, had complete evaluation of PELOD-2 score, and the blood culture results were included in this study. Sepsis was assessed with Indonesian Sepsis National Guidelines 2021. Performance analysis of the guidelines was conducted with SPSS version 25, by assessing sensitivity, specificity, accuracy, positive predictive value, negative predictive value, and likelihood ratio.
Results Two hundred subjects were enrolled in this study, of whom 52.5% were males.
Most subjects aged under one year (40.5%), and the most common infection was respiratory system (49%). A total of 63.5% were referral cases, with the length of stay in the previous hospital more than 48 hours (69.7%). There were 77% of subjects had antibiotics treatment at the previous hospital. As for outcomes, 63.5% survived and 36.5% died. The positivity rate of blood culture in this study was 19%. Performance evaluation of Sepsis Indonesian Sepsis National Guidelines 2021 revealed sensitivity 28.95%, specificity 87.65%, accuracy 76.5%, positive predictive value 35.48%, negative predictive value 84.02%, positive likelihood ratio 2.34 (95%CI 1.28 to 4.32) and negative likelihood ratio 0.81 (95%CI 0.7 to 0.94).
Conclusion Indonesian Sepsis National Guidelines 2021 (PNPK Sepsis 2021) has low sensitivity and high specificity in diagnosing bacterial sepsis.
Intermuscular adipose tissue accumulation is associated with higher tissue sodium in healthy individuals
Authors: Ertuglu Lale A. , Sahinoz Melis , Alsouqi Aseel , Deger Serpil Muge , Guide Andrew , Pike Mindy , Robinson‐Cohen Cassianne , Akwo Elvis , Pridmore Michael , Crescenzi Rachelle , Madhur Meena S. , Kirabo Annet , Harrison David G. , Luft Friedrich C. , Titze Jens , Ikizler T. Alp , Gamboa Jorge L. 
Published: July 2024

AbstractBackground and AimsHigh tissue sodium accumulation and intermuscular adipose tissue (IMAT) are associated with aging, type 2 diabetes, and chronic kidney disease. In this study, we aim to investigate whether high lower‐extremity tissue sodium accumulation relates to IMAT quantity and whether systemic inflammatory mediators and adipocytokines contribute to such association.MethodsTissue sodium content and IMAT accumulation (percentage of IMAT area to muscle area) were measured in 83 healthy individuals using sodium imaging (23Na‐MRI) and proton (1H‐MRI) imaging of the calf. Insulin sensitivity was assessed by glucose disposal rate (GDR) measured with the hyperinsulinemic‐euglycemic clamp.ResultsMedian (interquartile range) muscle and skin sodium contents were 16.6 (14.9, 19.0) and 12.6 (10.9, 16.7) mmol/L, respectively. Median IMAT was 3.69 (2.80, 5.37) %. In models adjusted for age, sex, BMI, GDR, adiponectin, and high‐sensitivity C‐reactive protein, increasing tissue sodium content was significantly associated with higher IMAT quantity (p = 0.018 and 0.032 for muscle and skin tissue sodium, respectively). In subgroup analysis stratified by sex, skin sodium was significantly associated with IMAT only among men. In interaction analysis, the association between skin sodium and IMAT was greater with increasing levels of high‐sensitivity C‐reactive protein and interleukin‐6 (p for interaction = 0.022 and 0.006, respectively).ConclusionsLeg muscle and skin sodium are associated with IMAT quantity among healthy individuals. The relationship between skin sodium and IMAT may be mediated by systemic inflammation.
Application of the Taguchi method and RSM for process parameter optimization in AWSJ machining of CFRP composite-based orthopedic implants
Authors: Kodandappa Ramesha , Nagaraja Santhosh , Chowdappa Manjunatha Matnahalli , Krishnappa Manjunath , Poornima Gubbi Shivarathri , Ammarullah Muhammad Imam 
Published: July 2024

Abstract
Abrasive water suspension jet (AWSJ) machining on carbon fiber-reinforced polymer (CFRP) composite-based orthopedic implants yielded insightful results based on experimental data and subsequent statistical validations. Underwater AWSJ cutting consistently outperformed free air cutting, with numerical findings demonstrating its superiority. For instance, at #100 abrasive size and 5 mm standoff distance (SOD), the material removal rate (MRR) peaked at 2.44 g/min with a kerf width of 0.89 mm and a surface roughness (SR) of 9.25 µm. Notably, the increase in abrasive size correlated with higher MRR values, such as achieving 2.15 g/min at #120 grit and 3 mm SOD. Furthermore, optimization techniques like the Taguchi method and response surface methodology (RSM) were applied to refine machining parameters. These methodologies enhanced MRR, exemplified by achieving 2.10 g/min with #120 abrasive size and 5 mm SOD in underwater cutting conditions. The research explored the impact of key process parameters, namely, the speed, feed, and SOD on the MRR, kerf width, and SR in both free air cutting and underwater cutting conditions, which is one of the novel research endeavors in the domain of abrasive jet machining of composites.
Humor in Chinese Traditions of Thought, Part One: Systematic Reflections in View of Ancient Confucian and Daoist Applications of Humor
Authors: Bartosch David 
Published: July 2024

Abstract
I argue that most of the pre-modern Chinese schools of thought contain elements of humor that can be analyzed in a differentiated and systematic manner. This article provides the first of two parts of this investigation. As a preparatory part, its scope is outlined on the basis of a traditional ideograph that represents the basic Chinese schools of thought as a whole. This is followed by an introduction to the present analytical framework. It is shown that it is compatible with the most basic ancient and modern concepts in the Chinese philosophy of humor. Based on this, the investigation turns to the Analects. It is shown that Confucius uses elaborate forms of humor as an allusive manner of teaching. Afterwards, the parallel Confucian refusal of comical entertainment and mass humor is discussed. A comparative discussion of evolved forms of humor in Confucian contexts and the Daoist classic Zhuangzi provides the transition to the more specific perspectives in the narrative of “Huzi, the Face Changer.” This is followed by a further in-depth comparison of Confucius and Zhuangzi’s high-level transformative humor. This leads to the discussion of the shielding function of humor as alluded to in the Daoist story of Hundun in the Zhuangzi.
Solid fuel use and low birth weight: a systematic review and meta-analysis
Authors: He Jie , Zhong Kangkang , Yang Rui , Wen Chuanting , Liu Shubo , Yang Yiping , Zhong Qi 
Published: July 2024

Abstract
Solid fuel use is increasingly linked to low birth weight (LBW), but conclusions were inconsistent. We aimed to summarize the association between solid fuel use and LBW. Twenty-one studies that met the inclusion criteria were identified through PubMed, Qvid Medline, and Web of Science databases. The final search occurred on March 20, 2024. Summary relative effect and 95 % confidence intervals were estimated with a random-effects model. Subgroup analyses and sensitivity analyses were performed to investigate possible sources of heterogeneity and to test the stability of the results. Nineteen studies evaluated the association between solid fuel use in pregnant woman and LBW (1.188 for solid fuels: 1.055 to 1.322). No significant heterogeneity was identified among the included studies (p=0.010, Tau2=0.02, I2=48.1 %). Subgroup analysis found positive correlations for Asia, data years prior to 2014, and rural studies (1.245 for Asia: 1.077 to 1.412; Tau2=0.03, I2=56.0 %; 1.243 for data years prior to 2014: 1.062 to 1.424; Tau2=0.04, I2=60.98 %; 1.514 for rural: 1.258 to 1.771; Tau2=0.00, I2=0.0 %). Our meta-analysis showed that solid fuel use in pregnant women had an impact on LBW. Measures and policies are also needed to promote energy conversion and to limit and reduce the use of solid fuels.
On the spectrum of tridiagonal matrices with two-periodic main diagonal
Authors: Dyachenko Alexander , Tyaglov Mikhail 
Published: July 2024

Abstract
We find the spectrum and eigenvectors of an arbitrary irreducible complex tridiagonal matrix with two-periodic main diagonal. This is expressed in terms of the spectrum and eigenvectors of the matrix with the same sub- and superdiagonals and zero main diagonal. Our result generalises some recent results where the latter matrix stemmed from certain discrete orthogonal polynomials including specific cases of the classical Krawtchouk and Hahn polynomials.
Linguistic typology in action: how to know more
Authors: Aikhenvald Alexandra Y. 
Published: July 2024

Abstract
Linguistic typology is an all-embracing discipline central for inductively-based cross-linguistic generalizations, supported by language facts. Firsthand investigation of previously undescribed languages from regions known for their linguistic diversity helps expand our knowledge about the nature of language and the parameters of cross-linguistic variation. We explore the options of marking commands in a non-main clause and the issue of associative non-singular number in Yalaku and in Manambu (from Papua New Guinea), before turning to nominal aspect and non-propositional evidentiality (exemplified with Tariana and Jarawara, from Brazilian Amazonia). Previously undescribed languages help typologists expand and test our analytic frameworks
FLEXIBILIZAÇÃO DE DIREITOS PELA VIA DO NEGOCIADO SOBRE O LEGISLADO: DUAS VISÕES DISTINTAS SOB A ÉGIDE DA LEI 13.467 DE 2017
Authors: Fernandes Bárbara Barbosa , Gurgel Christianne Moreira Moraes 
Published: July 2024

Resumo: O presente artigo explora a temática da flexibilização dos direitos trabalhistas pela via do negociado sobre o legislado trazida de forma expressa na Lei 13.467 de 2017, utilizando como parâmetro duas visões distintas. Adota-se uma análise positiva e negativa sobre o movimento flexibilizatório negocial, com a finalidade de se compreender um primeiro posicionamento consubstanciado na relevância da autonomia negocial, na preservação da empresa para que seja cumprida a função para a qual foi destinada, reconhecendo a possibilidade de uma flexibilização responsável de direitos. Quanto ao segundo posicionamento legitima-se a percepção de indisponibilidade absoluta de direitos laborais insuscetíveis de flexibilização, bem como afronta ao princípio da vedação do retrocesso social quando da flexibilização de direitos amparada por sindicatos que perderam legitimidade com o fim da contribuição obrigatória. Para essa análise, foi adotado o procedimento metodológico de revisão bibliográfica e levantamento documental. Palavras-chaves: flexibilização; negociação coletiva; autonomia negocial; função social da empresa; direitos indisponíveis; retrocesso social. Abstract: This article explores the theme of the flexibilization of labor rights through negotiations on the legislation expressly brought in by federal statute 13,467/2017, using as parameter two different views. A positive and negative analysis of the flexibilization of negotiations is adopted, with the purpose of understanding a first position embodied in the relevance of negotiating autonomy, in the preservation of the company so that the function for which it was intended is fulfilled, recognizing the possibility of a responsible flexibilization of rights. As for the second position, the perception of absolute non-disposability of labor rights that cannot be made more flexible is legitimized, as well as an affront to the principle of prohibition of social regression when the flexibilization of rights is supported by unions that have lost legitimacy with the end of the mandatory contribution. For this analysis, the methodological procedure of bibliographic review and documentary survey was adopted. Keywords: flexibilization; collective bargaining; negotiation autonomy; social function of the company; non-disposable rights; social regression. Sumário: Introdução. 1. A flexibilização no direito do trabalho. 1.1. Breve análise do instituto da flexibilização no direito do trabalho brasileiro. 1.2 MovimentoFlexibilizatório: AConstituiçãoFederalde 1988 e aLei 13.467 de 2017. 2. Princípios concercentes às negociações coletivas. 3. Flexibilização de direitos pela via do negociado sobre o legislado. 3.1 Visão positiva da flexibilização de direitos pela via do negociado sobre o legislado. 3.2 Visão negativa da flexibilização de direitos pela via do negociado sobre o legislado. Considerações finais. Referências.
PARALELO ENTRE AS SOLUÇÕES NEGOCIADAS NA ESFERA PENAL: MEDIAÇÃO X SUSPENSÃO PROVISÓRIA DO PROCESSO NO ORDENAMENTO JURÍDICO PORTUGUÊS
Authors: Migliati Gislaine Rosália 
Published: July 2024

Resumo: O presente artigo busca traçar uma comparação entre os institutos da mediação e da suspensão provisória do processo em Portugal, uma vez que ambos são considerados formas negociais na esfera penal. A principal finalidade é restabelecer o contato do ofensor com a sociedade, fazendo-o perceber e valorizar esta nova chance, uma vez que é parte ativa na consolidação deste novo compromisso em conjunto com a vítima, havendo uma descaracterização de conflito para consenso. Mediante a análise bibliográfica da doutrina, poderemos analisar e comparar o funcionamento destes institutos no ordenamento jurídico processual-penal, suas respectivas particularidades e procedimentos.Palavras-chave: Processo penal; Suspensão provisória do processo; Mediação penal; Métodos negociais; Consenso. Abstract: This article attempts to draw a comparison between mediation and provisional suspension in legal proceedings in Portugal, since both judicial measures are considered transitional solutions in criminal proceedings. The main purpose is to reestablish interaction from the offender with society, by aiding him to recognize and value this innovative opportunity, throughout his active participation in the consolidation of a cooperative settlement with the victim, and the conversion from conflict to consensus. By way of doctrinal bibliographic analysis, we were able to examine and compare the functioning of those legal institutes in criminal procedural law, with focus in its particularities and proceedings.Keywords: Criminal procedure; provisional suspension measures; criminal mediation; transitional methods; consensus. Sumário: Introdução. 1. Contexto histórico e evolução dos institutos. 1.1. Suspensão provisória do processo. 1.2. Mediação. 2. Peculiaridades da suspensão provisória do processo. 2.1. Conceito. 2.2. Princípios. 2.2.1. Legalidade. 2.2.2. Oportunidade. 2.2.3. Conflito entre princípio da legalidade e princípio da oportunidade? 2.3. Características e pressupostos processuais para concessão. 3. Peculiaridades da mediação. 3.1. Conceito. 3.2. Princípios. 3.2.1. Voluntariedade. 3.2.2. Confidencialidade. 3.2.3. Igualdade e imparcialidade. 4. Comparações: semelhanças e distinções. Conclusão. Referências.
REPRESENTAÇÕES SIMBÓLICAS DO ESTIGMA NA PRODUÇÃO TEXTUAL NA PENITENCIÁRIA ESTADUAL DO RIO GRANDE
Authors: Peixoto Cláudia Carneiro , Coronel Luciana Paiva 
Published: July 2024

RESUMO: O presente trabalho, vinculado ao Projeto de Extensão de Remição pela Leitura “Ler é Liberdade”, desenvolvido com doze presos, em isolamento, nas celas do denominado “seguro”, destinado, via de regra, a presos condenados por crimes contra a liberdade sexual, que sofrem ameaças de morte, membros de facções, e LGBTs, na Penitenciária Estadual do Rio Grande, objetiva, a partir da abordagem metodológica baseada na pedagogia de Paulo Freire, analisar a percepção do estigma provocado pelo sistema prisional. No primeiro encontro com os educandos do projeto, foi proposta uma atividade em cartolina, denominada “Meu mundo, minha palavra”, em que os educandos interagiam espontaneamente. As seguintes palavras foram aportadas: preconceito; respeito; atitude; compreensão; companheirismo; escutar; deserto; lembranças; carinho; solidariedade; cidadania; aprender mais; taxado; injustiça e impunidade. O léxico apresentado pelos educandos direcionou as reflexões nos encontros posteriores, seguidos pela leitura do livro O pequeno Príncipe. Destacamos a palavra “taxado”, conquanto tenha se sobressaído nas reflexões dos educandos além de estar presente em uma das imagens produzidas, na representação dos obstáculos enfrentados pelo egresso a fim de se inserir no mercado de trabalho. Em correspondência com a apreensão de estigma exposta por Goffman, os educandos percebem termo “taxado” no cotidiano prisional como um julgamento depreciativo que os define, inclusive para além da prisão e, em face do qual, um sentimento de impotência, injustiça, revolta e resignação se instala. Entendemos que a representação de sentimentos permite a apropriação da realidade e oportuniza uma pequena libertação simbólica do peso da experiência carcerária.