bluuebunny/crossref_metadata_2025_split huggingface dataset:
Réussir son insertion professionnelle : une analyse féministe de trajectoires sociales de femmes qui se sont engagées dans un processus d’alphabétisation
Authors: Savoie Lise , Gaudet Jeanne d’Arc 
Published: August 2013

Les auteures présentent les résultats d’une recherche qualitative portant sur la compréhension de la trajectoire professionnelle de femmes qui sont retournées aux études dans un programme d’alphabétisation. Une analyse de leur trajectoire sociale avant et après le processus d’alphabétisation permet de comprendre la manière dont divers espaces de socialisation (famille, école, formation) influent sur les formes de travail dans lesquelles ces femmes s’engagent. La recherche a d’ailleurs mis en perspective que ces femmes, après une formation en alphabétisation, s’orientent vers des secteurs d’emploi traditionnellement féminins : le soin aux autres. C’est dans ces filières d’emploi qu’elles disent se sentir reconnues et valorisées.
« Voir » la santé autrement : les constructions discursives de la santé de jeunes femmes vivant en situation de handicap visuel
Authors: Pouliot Annie , Rail Geneviève 
Published: August 2013

À partir d'une perspective poststructuraliste et féministe, les auteures explorent, dans le contexte du discours dominant de l'obésité, les constructions discursives de la santé de 20 jeunes femmes vivant en situation de handicap visuel. Dans un premier temps, elles utilisent l'écriture évocatrice afin de rapporter les résultats de l'analyse thématique. Cette dernière leur permet de mettre en scène deux résultats émergents: la santé est principalement construite en termes corporels et en tant que responsabilité individuelle liée à l'adoption de pratiques sanitaires. Dans un second temps, les récits des jeunes femmes sont examinés par l'entremise d'une analyse poststructuraliste du discours. À partir de celle-ci, les auteures notent les positions multiples et fluides que les jeunes femmes adoptent en tant que « sujets » : à certains moments en tant que sujets « néolibéraux », reproduisant sans les remettre en question les éléments de certains discours dominants de la santé et de l'obésité, mais à d'autres moments en tant que sujets « poststructuralistes », capables d'apporter un regard critique sur les discours dominants et ainsi de reconstruire la notion de santé autrement et de manière moins oppressive.
Les scripts sexuels des femmes de carrière célibataires dans les téléséries québécoises. Études de cas : Tout sur moi, Les hauts et les bas de Sophie Paquin et C.A.1
Authors: Lavigne Julie , Auger Anne-Marie , Lévy Joseph Josy , Engler Kim , Fernet Mylène 
Published: August 2013

Dans le contexte d'une recherche portant sur les femmes célibataires à Montréal, l'analyse de trois téléséries québécoises mises en ondes par Radio- Canada ayant comme personnage central une femme de carrière célibataire dans la trentaine (Tout sur moi, Les hauts et les bas de Sophie Paquin et C.A.) a été effectuée afin de dégager les représentations de leur vie sociosexuelle, et ce, à partir du concept d'agentivité sexuelle, de la théorie des scripts de la sexualité et celle des orientations intimes de soi. Les divers scénarios sexuels vécus par les trois personnages, des scripts de rencontre à ceux de rupture, en passant par les types de relations qui y sont rattachés, sont présentés.
L'analyse suggère une grande variabilité dans les scripts sexuels féminins et l'adoption de scripts considérés traditionnellement comme masculins : notamment, les femmes prennent souvent l'initiative de la rencontre et des rapports sexuels. Deux des trois personnages féminins étudiés possèdent des caractéristiques d'une orientation intime de soi du type « désir individuel », le troisième personnage présentant une construction de soi du type « réseau sexuel »; cependant, les trois personnages conservent certains aspects d'une orientation intime de soi de la sexualité conjugale. Ces téléséries présentent donc des personnages féminins multipartenaires, sans les confiner dans des rôles de femmes faciles et sans que cet aspect leur porte préjudice, ce qui laisse ainsi suggérer une transformation des représentations de la sexualité des femmes célibataires québécoises.
Gérald Leblanc et l’expérience du corps dans la ville
Authors: Ferron Andrée Mélissa 
Published: August 2013

Dans La condition urbaine, Olivier Mongin soutenait que « le premier langage qui permet de qualifier l’expérience urbaine est […] celui du poète et de l’écrivain, celui des mots et de leur rythmique. » (Mongin 2005 : 32). Mongin posait alors la question de l’implication du corps dans l’expérience de l’espace urbain traduite dans le texte. En littérature acadienne, il est difficile de songer à un exemple plus pertinent pour illustrer ces propos que celui de l’oeuvre de Gérald Leblanc. Dans un contexte de francophonie minoritaire, où l’espace demeure investi d’un récit de dépossession, Leblanc aura choisi de canaliser l’identité collective dans les possibles de l’expérience urbaine individuelle. Empirique, adoptant l’esprit jubilatoire que lui inspire l’espace monctonien pour libérer son identité acadienne de ses faux récits contraignants et restrictifs, le poète propose une « infinité de parcours » individuels (Mongin 2005 : 39-40) pour signifier l’appartenance collective.
Les défis du télétravail à l’égard de la vie privée du télétravailleur
Authors: Drolet Johanne , Lebnan Karim 
Published: August 2013

Comment le télétravail peut-il se mettre en place en droit québécois du travail
sans qu’il n’entraîne une violation injustifiée du droit au respect de la vie privée
des télétravailleurs à domicile ? Pour tenter de répondre à cette question, les
auteurs tracent d’abord un portrait du cadre juridique du droit du travail québécois
en ayant en tête son application au télétravail. Ensuite, ils passent en revue la
jurisprudence des tribunaux pour voir la portée que ceux-ci ont donnée au droit à la
vie privée. Enfin, les auteurs mettent en relief certains arguments justifiant une
pondération à la hausse de l’expectative raisonnable de la vie privée du
télétravailleur à domicile, le télétravailleur salarié n’ayant pas renoncé à son
droit à la vie privée du seul fait de sa subordination juridique à l’employeur. Qui
plus est, le télétravailleur à domicile exécute sa prestation de travail depuis le
domaine souverain de la vie privée, son domicile.
Prévenir les atteintes à la santé des travailleurs dans les opérations de sous-traitance et de mise à disposition de personnel
Authors: Abellard Stéphanie , Verkindt Pierre-Yves 
Published: August 2013

Le prêt de main-d’oeuvre à titre exclusif et à but lucratif est interdit en France. Les formes légales de mise à disposition de personnel et notamment le travail temporaire sont donc strictement encadrées. Leur utilisation fait l’objet d’un contrôle administratif et judiciaire strict. Ces formes de mise à disposition coexistent avec d’autres mécanismes rassemblés sous le vocable général de « sous-traitance ». Au sens strict, la sous-traitance consiste pour une entreprise à confier à une autre l’exécution partielle d’une tâche qui lui incombe. Au sens large, elle inclut la « sous-traitance » interne par laquelle une entreprise demande à une entreprise extérieure de réaliser des tâches sur son site. Dans tous les cas, ces techniques parfois appelées « d’externalisation » ont pour effet de faire coexister spatialement des travailleurs appartenant à des entreprises différentes. Cette coexistence augmente les risques d’accident dans un contexte où l’identification du « décideur » s’avère parfois difficile. Les prévenir suppose de tenir compte de la pluralité d’entreprises concernées et de chaînes de direction.
The 2012-2013 Influenza Epidemic and the Role of Osteopathic Manipulative Medicine
Authors: Mueller Donna M. 
Published: August 2013

Abstract
The 2012-2013 influenza epidemic arrived approximately 4 weeks early, augmented by an unusual variant type-A (“swine flu”) strain that caused greater-than-normal illness and a lack of efficacy in vaccination against it. Tens of thousands of people die of influenza or related complications during a nonepidemic influenza season. Osteopathic medicine can substantially help to address the complications that result from influenza. For example, during the deadly 1918-1919 Spanish influenza pandemic, osteopaths reduced patient mortality and morbidity by using lymphatic treatment techniques. Use of osteopathic manipulative treatment with vaccination, antiviral therapy, and chemoprophylaxis has potential to save lives and reduce complications. The present article describes the role of osteopathic manipulative treatment in the management of influenza and highlights current issues surrounding the use of antiviral therapy.
Role of Preoperative Sonography in the Diagnosis and Pathologic Staging of Pseudomyxoma Peritonei
Authors: Li Yanmi , Guo Aitao , Tang Jie , Wang Longxia , Wang Junyan , Yu Dejiang 
Published: August 2013

ObjectivesThe purpose of this study was to analyze the sonographic features of pseudomyxoma peritonei and the ability of preoperative sonography to assess the pathologic grades of this disease.MethodsNineteen patients with pseudomyxoma peritonei who underwent preoperative sonographic examinations were included (9 male and 10 female; age range, 31–70 years). Four patients presented with disseminated peritoneal adenomucinosis, 7 with peritoneal mucinous carcinomatosis with intermediate or discordant features (intermediate‐grade disease), and 8 with peritoneal mucinous carcinomatosis. The sonographic characteristics, clinical features, and serum tumor marker levels were recorded and compared among the 3 grades.ResultsClinical symptoms and carcinoembryonic antigen, cancer antigen 125 (CA‐125), CA‐19‐9, CA‐724, and CA‐153 levels were not significantly different among the 3 pathologic grades (P > .05). Ascites, scalloping of the visceral margin, invasive parenchymal nodules, and peritoneal masses were detected in all grades. Disseminated peritoneal adenomucinosis occurred without the finding of an omental cake. The presence of enlarged lymph nodes was more common in peritoneal mucinous carcinomatosis. The diagnosis of pseudomyxoma peritonei was made by preoperative sonography in 1 case. Four cases were diagnosed as ovarian mucinous cystadenoma with rupture. One case was diagnosed as a mucinous appendiceal cyst. Four cases were diagnosed as ascites or encapsulated effusion. One case was misdiagnosed as lymphoma. The others were diagnosed as celiac masses.ConclusionsPreoperative sonography can be used to diagnose pseudomyxoma peritonei as long as radiologists are familiar with the imaging features. Although there are overlaps in the sonographic findings among the different grades, some features may aid in separating them.
Evaluation of Screening Whole‐Breast Sonography as a Supplemental Tool in Conjunction With Mammography in Women With Dense Breasts
Authors: Chae Eun Young , Kim Hak Hee , Cha Joo Hee , Shin Hee Jung , Kim Hyunji 
Published: August 2013

ObjectivesThe purpose of this study was to evaluate the use and performance of supplemental screening whole‐breast sonography in conjunction with mammography in asymptomatic women with dense breast tissue.MethodsA total of 28,796 asymptomatic women underwent screening mammography. Among 20,864 women with dense breasts (72%), 8359 underwent additional sonography as part of their screening examinations. We classified women with mammographically dense breasts into mammography‐only and mammography‐plus‐sonography groups. The reference standard was a combination of pathologic results and clinical follow‐up at 2 years. We compared the recall rate, cancer detection yield, sensitivity, specificity, and positive predictive value in each group.ResultsAmong the 20,864 women with dense breasts, 35 cancers were diagnosed, with a mean size of 13 mm. The cancer detection yield was 0.480 per 1000 women in the mammography‐only group and increased to 2.871 in the mammography‐plus‐sonography group. Of 24 cancers detected in the mammography‐plus‐sonography group, the mean size was 11 mm, and the axillary lymph nodes were negative in 19 of 20. The sensitivity was significantly higher in the mammography‐plus‐sonography group than the mammography‐only group (100% versus 54.55%; P = .002). The positive predictive values of sonographically prompted biopsy were 11.1% for the mammography‐plus‐sonography group and 50% for the mammography‐only group.ConclusionsSupplemental screening whole‐breast sonography increases the cancer detection yield by 2.391 cancers per 1000 women with dense breast tissue over that of mammography alone. It is beneficial for increased detection of breast cancers that are predominantly small and node negative; however, it also raises the number of false‐positive results.
Improving Antenatal Prediction of Small‐for‐Gestational‐Age Neonates by Using Customized Versus Population‐Based Reference Standards
Authors: Landres Inna V. , Clark Aundrea , Chasen Stephen T. 
Published: August 2013

ObjectivesThe purpose of this study was to evaluate whether the use of customized fetal reference standards improves the prenatal detection of intrauterine growth restriction.MethodsWe conducted a retrospective cohort study. Singleton pregnancies with a diagnosis of a small‐for‐gestational‐age (SGA) fetus based on the in utero reference standard of Hadlock et al (Am J Obstet Gynecol 1985; 151:333–337; Radiology 1991; 181:129–133) were identified from our ultrasound database, and customized percentiles were calculated by adjusting for maternal height, weight, ethnicity, parity, and sex.ResultsA total of 300 pregnancies were identified as SGA by both the Hadlock and customized standards, and 60 were identified as SGA by the Hadlock standard only. Small‐for‐gestational age pregnancies identified by the Hadlock standard only were significantly less likely to have any abnormal sonographic findings, including an elevated head to abdominal circumference ratio (8.3% versus 21.7%; P = .019), oligohydramnios (3.3% versus 13%; P = .027), abnormal umbilical artery Doppler findings (3.4% versus 14.7%; P = .017), maternal hypertensive disease (3.3% versus 12.7%; P = .041), and preterm delivery (6.7% versus 27.7%; P < .001). There was no difference in neonatal intensive care unit admission rates; however, neonates identified as SGA by the Hadlock standard only were less likely to have a postnatal diagnosis of SGA (9.1% versus 78.3%; P < .001) and had a shorter neonatal intensive care unit stay (median, 2 versus 8 days; P < .001).ConclusionsUsing a customized standard, we have identified a population of pregnancies with low rates of antenatal complications and sonographic findings associated with pathologic growth. Adoption of customized standards to improve our antenatal detection rate of intrauterine growth restriction may decrease the need for intervention in healthy but constitutionally small fetuses.
Effect of B‐Mode Optimization Techniques on Fetal Bowel Echogenicity Using Computerized Image Analysis
Authors: Karayanni-Ammuri Rasha , Ohel Gonen , Degani Shimon , Zreik Amer , Odeh Marwan , Shapiro Israel , Leibovitz Zvi 
Published: August 2013

ObjectivesThe purpose of this study was to provide and compare measurable parameters for normal fetal bowel echogenicity under predefined B‐mode scanning presets.MethodsForty healthy fetuses underwent 14‐ to 17‐week ultrasound scans, and 40 underwent 21‐ to 25‐week scans. Sagittal, coronal, and axial fetal abdominal images were tested using predefined B‐mode presets. The presets differed from fundamental imaging by isolated activation of harmonic imaging, compound resolution imaging, speckle reduction imaging, focus and frequency composite imaging, and coded excitation imaging features. A transabdominal probe was used in all fetuses, and transvaginal images were added for the 14‐ to 17‐week scans. The images were studied with custom‐developed software, which provided a grayscale analysis of the pixels in the region of interest within the image. The mean brightness of the pixels from the fetal bowel area was calculated.ResultsThe 14‐ to 17‐week transabdominal scans showed significantly higher mean brightness on harmonic imaging compared to fundamental imaging (P < .01). Activation of coded excitation and compound resolution imaging in these scans resulted in a significant decrease in the mean brightness compared to fundamental imaging. Mean bowel brightness values on the 21‐ to 25‐week transabdominal scans did not differ significantly with the use of the different imaging presets compared to fundamental imaging.ConclusionsTransabdominal harmonic imaging in the early second trimester may significantly increase the mean brightness of the fetal bowel tissue. Contrarily, compound resolution imaging and coded excitation imaging produce the opposite effect on bowel echogenicity.
Airport apron capacity: estimation, representation, and flexibility
Authors: Mirkovic Bojana , Tosic Vojin 
Published: August 2013

SUMMARYThis paper addresses some important issues related to airport apron capacity planning and management. An overview of existing apron models for supporting planning studies and for optimizing available resources utilization is given, with an emphasis on analytical models for apron capacity estimation. Constraints on apron usage, physical and operational with respect to different users, are discussed in detail, together with their impact on apron capacity. Simple extension of existing apron capacity estimation models is suggested accounting for constraints both on aircraft types and dominant users. Further on, instead of expressing apron capacity through a single number, an apron capacity envelope is used to illustrate capacity changes, that is, an apron's ability to accept various mixes of dominant users in demand. The apron capacity envelope provides information on capacity for one apron configuration (with respect to stand size and policy of usage) and a given fleet mix, for different shares of dominant users in demand. Finally, apron capacity flexibility is discussed with respect to its role in apron capacity planning and management. It is suggested how to express and interpret apron capacity flexibility. Copyright © 2013 John Wiley & Sons, Ltd.
Leveraging systems biology approaches in clinical pharmacology
Authors: Melas Ioannis N. , Kretsos Kosmas , Alexopoulos Leonidas G. 
Published: August 2013

ABSTRACTComputational modeling has been adopted in all aspects of drug research and development, from the early phases of target identification and drug discovery to the late‐stage clinical trials. The different questions addressed during each stage of drug R&D has led to the emergence of different modeling methodologies. In the research phase, systems biology couples experimental data with elaborate computational modeling techniques to capture lifecycle and effector cellular functions (e.g. metabolism, signaling, transcription regulation, protein synthesis and interaction) and integrates them in quantitative models. These models are subsequently used in various ways, i.e. to identify new targets, generate testable hypotheses, gain insights on the drug's mode of action (MOA), translate preclinical findings, and assess the potential of clinical drug efficacy and toxicity. In the development phase, pharmacokinetic/pharmacodynamic (PK/PD) modeling is the established way to determine safe and efficacious doses for testing at increasingly larger, and more pertinent to the target indication, cohorts of subjects. First, the relationship between drug input and its concentration in plasma is established. Second, the relationship between this concentration and desired or undesired PD responses is ascertained. Recognizing that the interface of systems biology with PK/PD will facilitate drug development, systems pharmacology came into existence, combining methods from PK/PD modeling and systems engineering explicitly to account for the implicated mechanisms of the target system in the study of drug–target interactions. Herein, a number of popular system biology methodologies are discussed, which could be leveraged within a systems pharmacology framework to address major issues in drug development. © 2013 The Authors. Biopharmaceutics & Drug Disposition published by John Wiley & Sons, Ltd.
Management of reproduction and pregnancy complications in maternal obesity: Which role for dietary polyphenols?
Authors: Santangelo Carmela , Varì Rosaria , Scazzocchio Beatrice , Filesi Carmelina , Masella Roberta 
Published: August 2013

AbstractObesity is a global and dramatic public health problem; maternal obesity represents one of the main risk factors of infertility and pregnancy complications as it is associated with adverse maternal and offspring outcomes. In the last few years, adipose tissue dysfunction associated with altered adipocytokine secretion has been suggested to play a critical role in all the phases of reproductive process. Obesity is a nutrition‐related disorder. In this regard, dietary intervention strategies, such as high intake of fruit and vegetables, have shown significant effects in both preserving health and counteracting obesity‐associated diseases. Evidence has been provided that polyphenols, important constituents of plant‐derived food, can influence developmental program of oocyte and embryo, as well as pregnancy progression by modulating several cellular pathways. This review will examine the controversial results so far obtained on adipocytokine involvement in fertility impairment and pregnancy complications. Furthermore, the different effects exerted by polyphenols on oocyte, embryo, and pregnancy development will be also taken in account. © 2013 BioFactors, 40(1):79–102, 2014
Inhibition of hydroxycinnamic acid sulfation by flavonoids and their conjugated metabolites
Authors: Wong Chi Chun , Williamson Gary 
Published: August 2013

AbstractHydroxycinnamic acids and flavonoids are dietary phenolic antioxidants that are abundant in our diet. Hydroxycinnamic acids are highly sulfated in vivo, and sulfotransferases (SULTs), in particular SULT1A1, play a major role in their metabolism. Flavonoids are potent inhibitors of human SULTs. In this study, the potential metabolic interaction between dietary hydroxycinnamic acids and flavonoids was investigated. Flavonoids, such as luteolin, quercetin, daidzein, and genistein, are identified as potent inhibitors of hydroxycinnamic acid sulfation in human liver S9 homogenate with IC50 values <1 µM. The inhibitory activity was less potent in the human intestinal S9 homogenate. We also demonstrate that quercetin conjugates found in vivo (quercetin‐3‐O‐glucuronide, quercetin‐7‐O‐glucuronide, and quercetin‐3′‐O‐sulfate) moderately inhibited the sulfation of hydroxycinnamic acids in human liver S9. In an intact cellular system, human HepG2 cells, caffeic acid and ferulic acid sulfation was inhibited by luteolin and quercetin (IC50: 1.6–3.9 µM). Quercetin‐3′‐O‐sulfate weakly inhibited sulfation. Quercetin glucuronides, limited by their low cellular uptake, were ineffective. These data suggest that the inhibition of SULTs by flavonoids and in vivo flavonoid conjugates may modify the bioavailability of dietary hydroxycinnamic acids by suppressing their conversion to sulfated metabolites. © 2013 BioFactors, 39(6):644–651, 2013