bluuebunny/crossref_metadata_2025_split huggingface dataset:
Private Benefits and Product Market Competition
Authors: Thépot Jacques 
Published: December 2013

Bénéfices privés et concurrence sur le marché des produits Cet article traite de l’influence des bénéfices privés sur la valeur des entreprises en situation d’oligopole. Les bénéfices privés sont supposés générer des coûts qui sont transmis à travers la structure organisationnelle. Ils créent ainsi des distorsions de prix sur le marché de produits en aval. Nous montrons que cela peut affecter positivement le résultat (c’est-à-dire la valeur de marché) des entreprises puisque l’intensité de la concurrence est réduite par l’augmentation des coûts unitaires. En situation d’oligopole, l’extraction des bénéfices privés peut améliorer les profits tout en induisant une perte de bien-être : cela suggère que la gouvernance d’entreprise ne peut pas être dissociée de la politique de la concurrence, dans les secteurs où l’opportunisme managérial se traduit par des coûts d’exploitation. Classification JEL : G38, D43.
Revisiting the Balassa-Samuelson Model with Markup Variations
Authors: Restout Romain 
Published: December 2013

Un réexamen du modèle de Balassa-Samuelson en présence de taux de marge endogènes Cet article s’intéresse au rôle des variations des taux de marge lors de la transmission des chocs de productivité sectorielles et de dépenses publiques au prix relatif des biens non échangeables. Le modèle de Balassa-Samuelson dans lequel le marché des biens est parfaitement concurrentiel suggère que, premièrement, le prix relatif augmente de 1 % suite à une augmentation du rapport des productivités sectorielles de 1 %, et que, deuxièmement, les chocs de dépenses publiques n’ont aucun impact sur le prix relatif à long terme. Appliquant les méthodes de cointégration en panel à un groupe de quinze pays de l’OCDE, nos résultats empiriques rejettent ces deux prédictions. Au contraire, nous montrons qu’une hausse de la productivité relative entre les deux secteurs de 1 % augmente le prix relatif des biens non échangeables de seulement 0.70 % et qu’une augmentation de la part des dépenses publiques dans le PIB de 1 % entraîne une hausse du prix relatif d’environ 1 %. Cet article montre ensuite que ces faits empiriques peuvent être répliqués par un modèle d’économie ouverte à deux secteurs dans lequel les changements de la composition de la demande en biens non échangeables génèrent des variations endogènes des taux de marge. Classification JEL : E20, E62, F31, F41.
Evaluations affiliées, dotations initiales et la surenchère dans les prises de contrôle
Authors: Didier Hounwanou Dégnidé 
Published: December 2013

Nous considérons une prise de contrôle dans laquelle les motivations des repreneurs potentiels sont multiples et étudions l’impact du degré d’affiliation de leurs évaluations sur la stratégie optimale. Nous montrons que cet impact dépend du rapport des dotations initiales. Nous trouvons que lorsque les dotations initiales sont symétriques, la stratégie optimale des enchérisseurs est indépendante du degré d’affiliation de leurs évaluations. En revanche, lorsque les dotations initiales sont asymétriques, cet impact dépend du niveau du signal privé de l’enchérisseur. Si les acquéreurs potentiels surenchérissent en présence de dotations initiales, l’étendue de la surenchère décroît avec l’augmentation du degré d’affiliation lorsque le signal privé est inférieur un certain seuil. L’agressivité des enchérisseurs profite à la firme cible dont le revenu espéré augmente avec le degré d’affiliation des évaluations. Classification JEL : D44, D82.
Report of chronic myelogenous leukemia in chronic phase from, Asian Institute of Oncology, Mumbai, 2002-2010
Authors: Bansal Shweta , Advani S.H. 
Published: December 2013

AbstractChronic myeloid leukemia (CML) has paradigm shift in its treatment modality after the discovery of targeted therapy Imatinib. At our centre we collected data of 100 consecutive patients over a period of 8 years. The interesting finding in our study was difference in the survival of patients presenting in early chronic phase (81%) versus late chronic phase (16%). Also the patients with primary resistance did poorly compared to the patients who developed secondary resistance to Imatinib.
Report of chronic myeloid leukemia from Indira Gandhi Institute of Medical Sciences, Regional Cancer Center, 2002-2009
Authors: Prasad Rajiv Ranjan , Singh Pritanjali 
Published: December 2013

AbstractIndira Gandhi Institute of Medical Sciences, Regional Cancer Center was established in 1993. It′s one of the main Health-Care Institution in the state of Bihar. The data of 205 patients was presented in the ICON meeting and 98% of patients were diagnosed in chronic phase. Complete hematological response was seen in 91% of patients in 3 months. A total of 197 (96%) patients were alive at the time of analysis of which 179 (87%) were still in chronic phase with hematological remission.
Chronic myeloid leukemia treatment with Imatinib: An experience from a private tertiary care hospital
Authors: Doval D C , Batra Ullas , Goyal Sumit , Sharma Ajay , Azam Saud , Shirali Rashmi 
Published: December 2013

AbstractThe data presents 75 chronic myeloid leukemia patients diagnosed over a period 6 years i.e. from 2002 to 2008. The most common presentation was splenomegaly and 97% achieved complete hematological response at median duration of 4.3 weeks. The uniqueness of this study is follow-up with molecular response monitoring. Nearly, 30% patients achieved major molecular response (MMoR) by 12 months. 70% of patients achieved MMoR by median time of 60 months. Only 10% of the patient who achieved MMoR by 18 months had lost their responses subsequently.
Report of patients with chronic myeloid leukemia, from hematology clinic, Ahmedabad, Gujarat 2000-2010 at 1 st myelostone meeting: Indian evidence of chronic myelogenous leukemia
Authors: Deotare Uday R , Chudgar Urmish , Bhagat Eva 
Published: December 2013

AbstractThe data of 156 patients was presented from Hematology clinic, Ahmedabad. This hematology clinic caters large number of the population from Gujarat as well as from neighboring states such as Rajasthan and Madhya Pradesh. Out of 156 patients, 146 (94%) patients were in chronic phase. Complete hematological response was seen in 90% of patients and overall survival was 82% at 5 years.
Evidence for nonmigrating tides produced by the interaction between tides and stationary planetary waves in the stratosphere and lower mesosphere
Authors: Xu Jiyao , Smith A. K. , Liu Mohan , Liu Xiao , Gao Hong , Jiang Gouying , Yuan Wei 
Published: December 2013

AbstractIn this work, 11 years (2002–2012) of Thermosphere, Ionosphere, Mesosphere Energetics, and Dynamics/Sounding of the Atmosphere using Broadband Emission Radiometry (SABER) global temperature data are used to study the nonlinear interaction between stationary planetary waves (SPWs) and tides in the stratosphere and mesosphere. The holistic behavior of the nonlinear interactions between all SPWs and tides is analyzed from the point of view of energetics. The results indicate that the intensities of nonmigrating diurnal, semidiurnal, terdiurnal, and 6 h tides are strongest during winter and almost vanish during summer, synchronous with SPW activity. Temporal correlations between the SPWs and nonmigrating tides for these four tidal components are strong in the region poleward of 20° and below about 80 km. In the tropics, where the SPWs are very weak in all seasons, the correlations are small. Bispectral analysis between triads of waves and tides shows which particular interactions are likely to be responsible for the generation of the nonmigrating tides that are largest in the midlatitude stratosphere. Based on the more limited SABER observations at high latitudes, the correlations there are similar to those in midlatitudes during spring, summer, and autumn; there are no high‐latitude observations by SABER in winter. These results show that nonlinear interactions between SPWs and tides in the stratosphere and the lower mesosphere may be an important source of the nonmigrating tides that then propagate into the upper mesosphere and lower thermosphere.
Furfuryl alcohol functionalized graphene nanosheets for synthesis of high carbon yield novolak composites
Authors: Roghani‐Mamaqani Hossein , Haddadi‐Asl Vahid , Mortezaei Mehrzad , Khezri Khezrollah 
Published: December 2013

ABSTRACTGraphene oxide and furfuryl alcohol modified graphene nanosheets (G‐FA) were used to prepare graphene/novolak composites. Effect of graphene compatibilization on the properties of the composites especially carbon yield value is evaluated. Both types of graphene nanosheets were dispersed uniquely in the novolak matrix as proved by X‐ray diffraction analysis. However, modification of graphene sheets by furfuryl alcohol results in more improved dispersions. Thermogravimetric analysis confirms the elevated thermal stability of the nanocomposites in comparison with the neat novolak. In addition, G‐FA containing composites have higher carbon yield values. A shift in the wave number of characteristic bonds of graphene after oxidation and modification with furfuryl alcohol, OH, CO, and CO bonds, are seen in the Fourier transform infrared spectroscopy spectra. Raman results and scanning electron microscopy images show that graphene nanosheets reduced in size and wrinkled by oxidation and functionalization. Transmission electron microscopy image of the composite with 0.2 wt % of G‐FA reveals the presence of nanosheets with curvature. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2014, 131, 40273.
Modification of ibuprofen drug release from poly(ethylene glycol) layered silicate nanocomposites prepared by hot‐melt extrusion
Authors: Campbell Kayleen T. , Craig Duncan Q. M. , McNally Tony 
Published: December 2013

ABSTRACTComposites of the poorly water soluble drug ibuprofen, a nonsteroidal anti‐inflammatory commonly used for pain relief, with layered silicates (nanoclays) and a poly(ethylene glycol) (PEG) were prepared by hot melt extrusion. A highly intercalated and partially exfoliated morphology was determined using wide‐angle x‐ray diffraction, field emission scanning electron microscopy, and high‐resolution transmission electron microscopy. The crystalline content of PEG was significantly reduced, as shown by differential scanning calorimetry studies, as a consequence of the large surface area of clay platelets physically hindering polymer chain dynamics and, in the case of montmorillonite, by tethering of PEG via hydrogen bonding. Addition of layered silicate retarded the release of ibuprofen from the PEG matrix, even though the crystalline content of PEG was reduced. This study therefore indicates that drug release in solid dispersion systems may be modified or indeed tailored by the inclusion of layered silicates. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2014, 131, 40284.
Zinc oxide nanoparticles catalyze rapid hydrolysis of poly(lactic acid) at low temperatures
Authors: Qu Meng , Tu Huilin , Amarante Miranda , Song Yi‐Qiao , Zhu S. Sherry 
Published: December 2013

ABSTRACTPoly(lactic acid) (PLA), a biobased, degradable polymer has been used recently in the field of oil and gas. These applications require rapid hydrolytic degradation of PLA especially at low temperatures. This work reports a simple and ready‐to‐scale up chemistry of using zinc oxide nanoparticles (ZnO NPs) to catalyze the hydrolytic degradation of PLA at the temperatures well below its glass transition temperature. Furthermore, for the first time, we have applied the nondestructive analytical method of 1H T2 NMR relaxometry to measure the apparent rate constants of PLA hydrolysis in solid, heterogeneous/composite systems that have multiple and complex reaction kinetics. We demonstrate that the activation energy for ZnO catalyzed PLA hydrolysis is about 38% lower than that of pure PLA hydrolysis. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2014, 131, 40287.
A physiologically-based pharmacokinetic model for disposition of 2,3,7,8-TCDD in fathead minnow and medaka
Authors: Parhizgari Zahra , Li James 
Published: December 2013

Abstract

A physiologically-based pharmacokinetic model was developed for the disposition of 2,3,7,8-tetrachlorodibenzo-p-dioxin (2,3,7,8-TCDD) in 2 fish species—fathead minnow and medaka. The model was developed based on the empirical data on disposition of dioxins in fish tissues, as well as existing knowledge on the mechanisms of uptake, distribution, storage, and elimination of dioxins in various species (other than fish). The present study examined the applicability of mechanisms known to occur in other species for fish and concluded that the same mechanisms defined for disposition of 2,3,7,8-TCDD in (mostly) rodents can be applicable for the 2 fish species examined as well. Parameter values for the model were selected and/or calibrated using available databases. Model compartments included the gill, kidney, liver, and other richly-perfused tissues, as well as fat and other slowly-perfused tissues. The model was calibrated using 2 independent datasets for exposure of fathead minnow and medaka to 2,3,7,8-TCDD in water. The initial values of the model parameters were selected from several sources, and calibrated to represent the 2 exposure datasets. With very few exceptions, the estimated parameter values for the 2 species were comparable, and the final predictions were in strong agreement with the observations. The model developed in the present study can therefore be used in the prediction of the body burden of 2,3,7,8-TCDD in fathead minnow and medaka. Uncertainty in the model prediction as a result of variability in input parameters is discussed for the parameters with the highest impacts on the model outcome. Environ Toxicol Chem 2014;33:1064–1071. © 2014 SETAC
Bioaccumulation of triclosan and triclocarban in plants grown in soils amended with municipal dewatered biosolids
Authors: Prosser Ryan S. , Lissemore Linda , Topp Edward , Sibley Paul K. 
Published: December 2013

Abstract

Biosolids generally contain the microbiocidal agents triclosan (TCS) and triclocarban (TCC) that are persistent during wastewater treatment and sorp to organic material. The present study investigated the concentration of TCS in tissues of radish, carrot, and soybean grown in potted soil amended with biosolids. Highest mean concentrations of TCS in radish, carrot, and soybean root tissue midway through the life cycle were 24.8 ng/g, 49.8 ng/g, and 48.1 ng/g dry weight, respectively; by the conclusion of the test, however, concentrations had declined to 2.1 ng/g, 5.5 ng/g, and 8.4 ng/g dry weight, respectively. Highest mean concentrations of TCS in radish and carrot shoot tissue were 33.7 and 18.3 ng/g dry weight at days 19 and 45, respectively, but had declined to 13.7 ng/g and 5.5 ng/g dry weight at days 34 and 69, respectively. Concentration of TCS in all samples of soybean seeds was below method detection limit (i.e., 2.8 ng/g dry wt). The present study also examined the concentration of TCS and TCC in edible portions of green pepper, carrot, cucumber, tomato, radish, and lettuce plants grown in a field amended with biosolids. Triclosan was detected only in cucumber and radish up to 5.2 ng/g dry weight. Triclocarban was detected in carrot, green pepper, tomato, and cucumber up to 5.7 ng/g dry weight. On the basis of the present study and other studies, we estimate that vegetable consumption represents less than 0.5% of the acceptable daily intake of TCS and TCC. These results demonstrate that, if best management practices for land application of biosolids in Ontario are followed, the concentration of TCS and TCC in edible portions of plants represents a negligible exposure pathway to humans. Environ Toxicol Chem 2014;33:975–984. © 2014 SETAC
Source apportionment of polycyclic aromatic hydrocarbons (PAHs) into Central Park Lake, New York city, over a century of deposition
Authors: Yan Beizhan , Bopp Richard F. , Abrajano Teofilo A. , Chaky Damon , Chillrud Steven N. 
Published: December 2013

Abstract

Relative contributions of polycyclic aromatic hydrocarbons (PAHs) from combustion sources of wood, petroleum, and coal were computed in sediments from Central Park Lake in New York City (NY, USA) by chemical mass balance based on several reliable source indicators. These indicators are the ratio of retene to the sum of retene and chrysene, the ratio of 1,7-dimethylphenanthrene (DMP) to 1,7-DMP and 2,6-DMP, and the ratio of fluroanthene to fluroanthene and pyrene. The authors found that petroleum combustion–derived PAH fluxes generally followed the historical consumption data of New York State. Coal combustion-derived PAH flux peaked approximately in the late 1910s, remained at a relatively high level over the next 3 decades, then rapidly declined from the 1950s to the 1960s; according to historical New York State coal consumption data, however, there was a 2-peak trend, with peaks around the early 1920s and the mid-1940s. The 1940s peak was not observed in Central Park Lake, most likely because of the well-documented shift from coal to oil as the major residential heating fuel in New York City during the late 1930s. It was widely believed that the decreased PAH concentrations and fluxes in global sediments during the last century resulted from a major energy shift from coal to petroleum. The data, however, show that this shift occurred from 1945 through the 1960s and did not result in an obvious decline. The sharpest decrease, which occurred in the 1970s was not predominantly related to coal usage but rather was the result of multiple factors, including a decline in petroleum usage largely, the introduction of low sulfur–content fuel in New York City, and the introduction of emission-control technologies. Environ Toxicol Chem 2014;33:985–992. © 2014 SETAC
1,2-dibromo-4-(1,2 dibromoethyl) cyclohexane (TBECH)–mediated steroid hormone receptor activation and gene regulation in chicken LMH cells
Authors: Asnake Solomon , Pradhan Ajay , Banjop-Kharlyngdoh Joubert , Modig Carina , Olsson Per-Erik 
Published: December 2013

Abstract

The incorporation of brominated flame retardants into industrial and household appliances has increased their occurrence in the environment, resulting in deleterious effects on wildlife. With the increasing restraints on available compounds, there has been a shift to using brominated flame retardants that has seen the production of alternative brominated flame retardants such as 1,2-dibromo-4-(1,2 dibromoethyl) cyclohexane (TBECH), which has been detected in the environment. In previous in silico and in vitro studies the authors have shown that TBECH can activate both the human androgen receptor (hAR) and the zebrafish AR (zAR) suggesting that it is a potential endocrine disruptor. The present study was aimed at determining the interaction of TBECH with the chicken AR (cAR). In the present study, TBECH bound to cAR, but in vitro activation assay studies using the chicken LMH cell line showed it had a potency of only 15% compared with testosterone. Sequence difference between ARs from different species may contribute to the different responses to TBECH. Further quantitative reverse-transcriptase polymerase chain reaction (qRT-PCR) analysis showed that TBECH interacted with and altered the expression of both thyroid receptors and estrogen receptors. In addition, the qRT-PCR analysis showed that TBECH altered the transcription pattern of genes involved in inflammatory, apoptotic, proliferative, DNA methylation, and drug-metabolizing pathways. This demonstrates that TBECH, apart from activating cAR, can also influence multiple biological pathways in the chicken. Environ Toxicol Chem 2014;33:891–899. © 2013 SETAC
Glioma Risks Associate With Genetic Polymorphisms of XRCC1 Gene in Chinese Population
Authors: Feng Xingjun , Miao Guozhuan , Han Yipeng , Xu Yi , Wu Huayun 
Published: December 2013

ABSTRACTGlioma is the most common type of primary brain tumors in adults. Previous evidence indicates that the X‐ray repair cross‐complementing group 1 gene (XRCC1) is an important candidate gene which influencing the pathogenesis of glioma. This study aims to assess the potential associations between glioma risks and genetic polymorphisms of XRCC1 gene. A total of 1,286 Chinese Han ethnic subjects consisting of 638 glioma patients and 648 controls were recruited in this case‐control study. The genotyping of XRCC1 genetic polymorphisms (c.482C>T, c.1161G>A, and c.1804C>A) were conducted using the polymerase chain reaction‐restriction fragment length polymorphism (PCR‐RFLP), created restriction site‐PCR (CRS‐PCR) and DNA sequencing methods. Our data indicated that the allelic and genotypic frequencies of these genetic polymorphisms in glioma patients were significantly different from those of controls. We detected that the alleles/genotypes were statistically associated with the increased risks of glioma (for c.482C>T, TT versus (vs.) CC: OR = 2.24, 95% CI = 1.48–3.39, P < 0.001; T vs. C: OR = 1.30, 95% CI = 1.09–1.53, P = 0.003; for c.1161G>A, AA vs. GG: OR = 1.62, 95% CI = 1.11–2.35, P = 0.012; A vs. G: OR = 1.19, 95% CI = 1.01–1.41, P = 0.040; for c.1804C>A, AA vs. CC: OR = 2.12, 95% CI = 1.45–3.11, P < 0.001; A vs. C: OR = 1.32, 95% CI = 1.12–1.56, P = 0.001). Our findings suggest that these genetic polymorphisms of XRCC1 gene may influence glioma risks in Chinese Han ethnic subjects, and might be potential molecular markers for evaluating glioma risks. J. Cell. Biochem. 115: 1122–1127, 2014. © 2013 Wiley Periodicals, Inc.
Down Regulation of miR200c Promotes Radiation‐Induced Thymic Lymphoma by Targeting BMI1
Authors: Cui Jianguo , Cheng Ying , Zhang Pei , Sun Mingjuan , Gao Fu , Liu Cong , Cai Jianming 
Published: December 2013

ABSTRACTThe miR‐200c has recently been implicated in the epithelial to mesenchymal transition (EMT) process by directly target the EMT related transcriptional factors ZEB1 and ZEB2. The expression of this miRNA is inversely correlated with tumorgenecity and invasiveness in several human cancers. However, little is known about the expression and targets of the miR‐200c in radiation carcinogenesis. Here in this study, using a split radiation induced thymic lymphoma (RITL) model in BALB/c mice, we found that miR‐200c is down‐regulated in RITL samples. Cell death and apoptosis in lymphoma cells was induced by miR‐200c mimic while decreased by miR‐200c inhibitor. Computational analysis found a putative target site of miR‐200c in the 3′UTR of one of the polycomb group (PcG) protein BMI1 mRNA, which was verified by a luciferase reporter assay. Forced over‐expression of miR‐200c decreased the level of BMI1 protein and moreover, over‐expression of BMI1 rescued the biological effects of miR‐200c, indicating BMI1 is a direct mediator of miR‐200c functions. Furthermore, the BMI1 expression level was up‐regulated and inversely correlated with miR‐200c in RITL samples. Finally, our data also indicates that Adenovirus over‐expression of pre‐miR‐200c reduced tumorgenesis in vivo. Taken together, we conclude that down‐regulated expression of miR‐200c and up‐regulation of its direct target BMI1 in radiation‐induced thymic lymphoma, which may indicate a novel therapeutic method for RITL through induction of miR‐200c or inhibition of BMI1. J. Cell. Biochem. 115: 1033–1042, 2014. © 2013 Wiley Periodicals, Inc.