bluuebunny/crossref_metadata_2025_split huggingface dataset:
From illustrations to an interactive art installation
Authors: Pavlin Erika , Elsner Žiga , Jagodnik Tadej , Batagelj Borut , Solina Franc 
Published: May 2015

Purpose– The purpose of this paper is to set an example of how people with severe learning difficulties could be more integrated into our society.Design/methodology/approach– The installation consists of puzzles in the form of a specially designed table with an integrated touch screen. As the visual templates for the puzzles serve pictures painted by a person with severe learning difficulties. The pieces of the puzzles are manipulated directly by the player on the touch screen presenting an intuitive and easily learned user interface.Findings– The framework for the work was a creation of an interactive art installation in the form of a game where users assemble puzzles on a touch monitor, housed in a specially designed table. Paintings by a person with severe learning difficulty served as visual templates for the puzzles. The pieces of the puzzles can be manipulated directly by the user on a touch screen presenting an intuitive and easily learned user interface, which stimulates the learning of fine motor skills and encourages practice, thus making it suitable for persons with severe learning difficulties in an art therapy setting.Practical implications– As the work has the format of an interactive art installation, this enables it to gain publicity through exhibitions in art galleries.Social implications– The installation demonstrates how people with severe learning difficulties can be integrated into the broader society. At the same time, these people are encouraged to use modern computer information technology, which is becoming a necessity also for this group of users. Ethical issues regarding how this group of people can get involved in such work are also discussed.Originality/value– Combining the habituation of people with severe learning difficulties with computer technology in the form of a game, and framing the whole process as a fine art undertaking, to win the public recognition, is a novelty in addressing the needs of these people.
Applying classification controls to Internet content in Australia
Authors: Leitch Shona , Warren Matthew 
Published: May 2015

Purpose
– The purpose of this study is to explore Australian public and stakeholders views towards the regulation of the Internet and its content. The federal government called for submissions addressing their proposal, and this paper analyses these submissions for themes and provides clarity as to the Australian public and stakeholders key concerns in regards to the proposed policy.

Design/methodology/approach
– The paper uses a qualitative approach to analyse the public consultations to the Australian Federal Government. These documents are coded and analysed to determine negative and positive viewpoints.

Findings
– The research has shown, based upon the analysis of the consultation, that there was no public support for any of the measures put forward, that the Australian Federal Government in its response has not recognised this public feedback and instead has only utilised some of the qualitative feedback obtained through the public consultation process to try to justify its case to proceed with its proposals.

Research limitations/implications
– The study is focussed on Australia.

Practical implications
– The paper analyses a proposed national approach to filtering the content of the Internet and discussed the public reaction to such an approach.

Social implications
– The paper looks at how different parts of Australian society view Internet filtering in a positive or negative manner.

Originality/value
– The only study that directly looks at the viewpoint of the Australian public.
Ex‐ante Evaluation of Policy Measures: Effects of Reward and Punishment for Fertiliser Reduction in Palm Oil Production
Authors: Moser Stefan , Mußhoff Oliver 
Published: May 2015

AbstractPalm oil production creates negative externalities, e.g. through intensive fertiliser application. Policies to limit externalities need an effective, sustainable and efficient measure We use a business simulation game in a framed field experiment in Indonesia to test ex‐ante different incentives for reducing such negative externalities. This setting allows inclusion of adequate contextual features, required for reasonable ex‐ante evaluation of policy measures. The different designs of the test incentives (either a reward or punishment) varied in their magnitude and probability of occurrence but with constant effects on expected income. Results show that participants react differently to these incentives, indicating that the design can contribute significantly to effectiveness, sustainability or efficiency. A high reward with a low probability was found to be the most effective and sustainable incentive. Moreover, for the most efficient design, a low and certain reward is indicated.
Systematic analysis of design and stratification for phase III trials in first‐line advanced non‐small cell lung cancer
Authors: Komiya Takefumi , Perez Raymond P. , Erickson Kirsten D. , Huang Chao H. 
Published: May 2015

AbstractBackgroundA recent study reviewed phase III trials of first‐line advanced non‐small cell lung cancer (NSCLC) conducted from 1981 to 2010, and provided trends in the study outcome. However, such trials have never been analyzed in detail for design and stratification factors.MethodsPhase III studies of systemic treatment for first‐line advanced or metastatic NSCLC published in English literature between 1981 and 2010 were identified. Characteristics, including sample size, number of trials, region, rate of meeting accrual goal, primary endpoint, type of phase III, interim analysis, allocation method, and stratification factors, were determined for each decade.ResultsA total of 162 studies met the criteria. The number of studies and sample size increased over the three decades. The primary endpoint was reported more frequently in recent decades, and non‐overall survival endpoints were chosen in European and Asian studies. Interim analysis was conducted more commonly during the 2000s. Allocation method was rarely reported throughout the three decades. The number of stratification factors increased significantly from one in 1980s to three in 2000s. Performance status, stage, and institution were most frequently selected, and at least one of the three factors was used in most of the studies in the 2000s. However, there are many other stratification factors that were used infrequently.ConclusionsDespite Consolidated Standards of Reporting Trials guidelines, allocation method has rarely been reported. The choice of stratification factor remains inconsistent across studies.
Agreement Between Experts Regarding Assessment of Postoperative Urinary Elimination Nursing Outcomes in Elderly Patients
Authors: Bitencourt Graziele Ribeiro , Alves Luise de Almeida Ferreira , Santana Rosimere Ferreira , Lopes Marcos Venicios de Oliveira 
Published: May 2015

PurposeThis study aims to verify the interrater reliability for indicators of the Nursing Outcomes Classification of urinary elimination.MethodsA total of 103 elderly postoperative patients were followed by two nurses with specialized training in medical‐surgical and gerontological nursing.FindingsThe agreement of evaluators was based on interpretation of the Krippendorff's alpha coefficient, for complete emptying of the bladder (.928) and presence of leukocytes (.885). The amount of urine (.262), density (.425), and urinary frequency (.307) had the lowest rates of agreement.Implications for Nursing PracticeAnalysis of urinary elimination could help in clinical follow‐up of elderly postoperative patients and selection of nursing interventions.
Defining Characteristics and Related Factors of Decreased Cardiac Tissue Perfusion: Proposal of a New Nursing Diagnosis
Authors: Santos Vinicius Batista , Atallah Álvaro Nagib , Lopes Camila Takáo , Lopes Juliana de Lima , Bottura Leite de Barros Alba Lúcia 
Published: May 2015

PurposeTo identify the possible defining characteristics (DCs) and related factors of the nursing diagnosis (ND) decreased cardiac tissue perfusion.MethodsCross‐sectional study using medical charts of adults admitted to an emergency department with the chief complaint of chest pain in a hospital in São Paulo, Brazil.FindingsDCs identified: crushing chest pain, elevated markers of myocardial necrosis, ischemic electrocardiogram changes, sweating, nausea, and vomiting. Related factors identified: interruption of arterial blood flow and coronary spasm.ConclusionThis ND was clinically identified due to significant differences in the DCs of patients with and without the diagnosis.Practice ImplicationsThe clinical indicators identified in this study can be the starting point for the DCs for this ND.
Effects of single‐shot and steady‐state propofol anaesthesia on rocuronium dose–response relationship: a randomised trial
Authors: Stäuble C. G. , Stäuble R. B. , Schaller S. J. , Unterbuchner C. , Fink H. , Blobner M. 
Published: May 2015

BackgroundSimilar to volatile anaesthetics, propofol may influence neuromuscular transmission. We hypothesised that the administration of propofol influenced the potency of rocuronium depending on the duration of the administration.MethodsAfter consent, patients scheduled for elective surgery randomly received rocuronium either after induction of anaesthesia with propofol (2 min of propofol, n = 36) or after 30 min of propofol infusion (30 min of propofol, n = 36). Remifentanil was given in both groups. Neuromuscular monitoring was performed by calibrated electromyography. The dose–response relationship of rocuronium was determined with a single‐bolus technique (0.07, 0.1, 0.15, 0.2, 0.3 and 0.45 mg/kg rocuronium). The primary endpoints were the ED50 and ED95 of rocuronium after 2 and 30 min propofol. Data are presented as means with (95% confidence interval). The trial is registered with the Eudra‐CT: 2009‐012815‐16.ResultsA total of 72 patients were included. Time to maximal neuromuscular blockade was significantly shorter in patients after 30 min of propofol [3.3 min (2.9–3.7)] compared with patients anaesthetised with 2 min of propofol [4.6 min (4.0–5.2)]. After 30 min of propofol, the slope of the dose–response curve was significantly steeper (30 min of propofol: 4.34 [3.62–5.05]; 2 min of propofol: [3.34 (2.72–3.96)], resulting in lower ED95 values of rocuronium (30 min of propofol: 0.287 mg/kg [0.221–0.368]; 2 min of propofol [0.391 mg/kg (0.296–0.520)]. The ED50 were not different between groups.ConclusionThe potency of rocuronium was significantly enhanced after propofol infusion for 30 min. Estimates of potency those are usually determined during steady‐state anaesthesia might underestimate rocuronium requirements for endotracheal intubation at the time of induction.
Ethnic disparities in thyroid surgery outcomes in New Zealand
Authors: Kwon Hyok Jun , Morton Randall P. 
Published: May 2015

AbstractBackgroundAlthough thyroid disease is known to have significant ethnic variability, ethnic disparities in outcomes of thyroid surgery have been poorly studied.MethodRetrospective review of 716 consecutive thyroid operations at Counties Manukau Health, a public health provider in New Zealand, from January 2002 to August 2013.ResultsCompared with Europeans, Māori and Pacific Islanders have longer operation times (P < 0.001) and heavier thyroid glands (P < 0.001). Polynesians also had higher risk of post‐operative haemorrhage compared with non‐Polynesians (P = 0.016). They also have higher body mass index, American Society of Anesthesiologists scores and rates of smoking. There were no differences in length of inpatient stay and readmission rates.ConclusionsThere are significant ethnic differences in certain outcomes of thyroid surgery. Part of this may be explained by higher co‐morbid characteristics.
Minimally invasive Ivor–Lewis oesophagectomy is a feasible and safe approach for patients with oesophageal cancer
Authors: Mei Xinyu , Xu Meiqing , Guo Mingfa , Xie Mingran , Liu Changqing , Wang Zhou 
Published: May 2015

AbstractBackgroundMinimally invasive approaches are increasingly being used in oesophagectomy. The aim of this study was to compare the short‐term clinical outcomes of the minimally invasive Ivor–Lewis oesophagectomy (MIILE) technique with those of the open Ivor–Lewis oesophagectomy (OILE) technique.MethodsWe identified 131 patients who underwent MIILE combined with thoracoscopy and laparoscopy. These patients were compared with 248 patients who underwent OILE between January 2012 and December 2013.ResultsMIILE and OILE produced similar post‐operative hospital mortality (MIILE 2.3 versus OILE 2%; P = 1.000). The MIILE approach was associated with a significant decrease in the time until chest drain removal (MIILE 9.07 ± 5.075 days versus OILE 11.26 ± 6.989 days; P = 0.002) and post‐operative length of stay (MIILE 10.89 ± 4.976 days versus OILE 12.83 ± 6.921 days; P = 0.002). Pneumonia was the most common complication in both groups. MIILE patients exhibited a lower incidence of post‐operative pneumonia (MIILE 17.6% versus OILE 28.2%; P = 0.024) compared with OILE. The survival rate did not significantly differ between the MIILE and OILE groups (1‐year survival rates: MIILE 86 versus OILE 88.2%; P = 0.537).ConclusionsIn this study, we demonstrate that MIILE is a feasible and safe approach for patients with middle or lower oesophageal cancer.
Combined metformin‐clomiphene in clomiphene‐resistant polycystic ovary syndrome: a systematic review and meta‐analysis of randomized controlled trials
Authors: Abu Hashim Hatem , Foda Osama , Ghayaty Essam 
Published: May 2015

AbstractObjectiveOur objective was to compare the effectiveness of metformin plus clomiphene citrate vs. gonadotrophins, laparoscopic ovarian diathermy, aromatase inhibitors, N‐acetyl‐cysteine and other insulin sensitizers+clomiphene for improving fertility outcomes in women with clomiphene‐resistant polycystic ovary syndrome.DesignPubMed, SCOPUS and CENTRAL databases were searched until April 2014 with the key words: PCOS, polycystic ovary syndrome, metformin, clomiphene citrate, ovulation induction and pregnancy. The search was limited to articles conducted with humans and published in English.SampleThe PRISMA statement was followed. Twelve randomized controlled trials (n = 1411 women) were included.Main outcome measuresOvulation and clinical pregnancy rates per woman randomized.ResultsCompared with gonadotrophins, the metformin+clomiphene combination resulted in significantly fewer ovulations (odds ratio 0.25; 95% confidence interval 0.15–0.41; p < 0.00001, 3 trials, I2 = 85%, n = 323) and pregnancies (odds ratio 0.45; 95% confidence interval 0.27–0.75; p = 0.002, 3 trials, I2 = 0%, n = 323). No significant differences were found when metformin+clomiphene was compared with laparoscopic ovarian diathermy (odds ratio 0.88; 95% confidence interval 0.53–1.47; p = 0.62, 1 trial, n = 282; odds ratio 0.96; 95% confidence interval 0.60–1.54; p = 0.88, 2 trials, I2 = 0%, n = 332, for ovulation and pregnancy rates, respectively). Likewise, no differences were observed in comparison with aromatase inhibitors (odds ratio 0.88; 95% confidence interval 0.58–1.34; p = 0.55, 3 trials, I2 = 3%, n = 409; odds ratio 0.85; 95% confidence interval 0.53–1.36; p = 0.50, 2 trials, n = 309, for ovulation and pregnancy rates, respectively).ConclusionsThere is evidence for the superiority of gonadotrophins, but the metformin+clomiphene combination is mainly relevant for clomiphene‐resistant polycystic ovary syndrome patients and, if not effective, a next step could be gonadotrophins. More attempts with metformin+clomiphene are only relevant if there is limited access to gonadotrophins.
THE MARKET SHARE OF NONPROFIT AND FOR‐PROFIT ORGANIZATIONS IN THE QUASI‐MARKET: JAPAN'S LONG‐TERM CARE SERVICES MARKET
Authors: KANAYA Nobuko , TAKAHASHI Hiromasa , SHEN Junyi 
Published: May 2015

ABSTRACTThis study uses a prefectural panel data set to examine the factors that affect the market share of nonprofit and for‐profit providers in Japan's long‐term care insurance system. Here, we focus on the market size and potential, asymmetric information, and the voluntarism environment. Our findings are as follows: (1) nonprofit organizations have a larger market share in areas with relatively unprofitable market conditions; (2) in the case of asymmetric information, experienced nonprofit providers, including government‐driven and partial nonprofit providers, have a larger market share than citizen‐driven nonprofit and for‐profit providers; and (3) citizen‐driven nonprofit providers have a larger market share in areas with more active civic voluntarism.
THE ROLE OF PROXIMITY IN VALUE PREFERENCES: A STUDY OF CONSUMER CO‐OPERATIVES
Authors: BYRNE Noreen , HEINONEN Kristina , JUSSILA Iiro 
Published: May 2015

ABSTRACTProximity is seen as an essential part of the relationship between a co‐operative and its members, one that is a source of member value and competitive advantage. As the restructuring trend in co‐operatives has tended towards scale and centralization, proximity to the member decreases. Thus, proximity between the members and the co‐operative is a major challenge. Still, proximity has received limited attention in both the co‐operative and consumer (member) value literature. The purpose of this paper is to begin filling this gap by investigating the relationship between proximity (both spatial and non‐spatial) and members' value preferences in a co‐operative. Our findings based on a credit union member survey indicate that in terms of member value preferences, spatial proximity has an indirect impact and non‐spatial proximities impact directly on member value preferences. Implications of the study are discussed.
SOCIAL JUSTICE AND THE FUTURE OF THE SOCIAL ECONOMY
Authors: VAN PARIJS Philippe 
Published: May 2015

ABSTRACTA just society is a society whose institutions sustainably secure the greatest possible real freedom to those with least real freedom. It must comprise a ‘social economy’ for two reasons : (1) its greater ability to achieve a fruitful combination between the flexibility it shares with the for‐profit sector and the trust it shares with the public sector; (2) its ability to mobilize ‘self exploitation’ and thereby to meet many needs that could only be met by the other two sectors at a prohibitive price. Moreover, a just society requires the introduction of an unconditional basic income, which provides a simple, non‐intrusive way of systematically encouraging and stabilizing the social economy.
Antipsychotics as antidepressants
Authors: Roberts Rona Jeannie , Lohano Kavita K. , El‐Mallakh Rif S. 
Published: May 2015

AbstractThree second‐generation antipsychotic (SGA) agents have received FDA approval for adjunctive treatment, to antidepressant, of major depressive disorder: quetiapine, aripiprazole, and olanzapine. Additionally, quetiapine and lurasidone have been approved for the treatment of bipolar depression. There are data suggesting that quetiapine is effective for major depressive disorder as monotherapy. These agents are effective for depression only at subantipsychotic doses. Receptor profiles predict that all SGA will have anxiolytic effects as subantipsychotic doses but that all will be dysphorogenic at full antipsychotic doses (i.e., produce a depression‐like clinical picture). The antidepressant effect appears to be unique to some agents, with direct evidence of insignificant antidepressant action for ziprasidone. Three general principles can guide the use of antipsychotics as antidepressants: (i) All SGAs may have anxiolytic effects; (ii) full antipsychotic doses are dysphorogenic, and therefore, subantipsychotic doses are to be used; and (iii) SGAs do not have a general antidepressant effect, rather, this appears to be unique to quetiapine and aripiprazole, and possibly lurasidone.
Significance of the Immunohistochemical Expression of Bone Morphogenetic Protein‐4 in Bone Maturation after Maxillary Sinus Grafting in Humans
Authors: Torrecillas‐Martínez Laura , Galindo‐Moreno Pablo , Ávila‐Ortiz Gustavo , Ortega‐Oller Inmaculada , Monje Alberto , Hernández‐Cortés Pedro , Aguilar David , O'Valle Francisco 
Published: May 2015

AbstractBackgroundBone morphogenetic proteins (BMPs) are members of the transforming growth factor‐β (TGFβ) protein superfamily and are known to be involved in bone and cartilage formation. Within this family, BMP‐4 is one of the most studied members. It has been shown to induce osteogenic differentiation of osteoblasts and osteoprogenitor cells in vitro, but the intimate processes in which this protein promotes and regulates osseous repair still remains unclear.PurposeTo assess whether the native cellular immunohistochemical expression of BMP‐4 correlates with the maturation of bone samples obtained at 6 months after maxillary sinus augmentation.Materials and MethodsHistopathological and histomorphometrical analyses were performed in all the samples, which were obtained from a total of 58 patients. Immunohistochemical expression of BMP‐4 was analyzed in 30 core biopsies obtained from maxillary sinuses grafted with a combination of anorganic bovine bone and autogenous cortical bone [1:1] (AB‐group), and 18 biopsies from maxillary sinuses grafted solely with a cortico‐cancellous particulate allograft (M‐group), all of them after a 6‐month healing period. Also, 10 biopsies of native pristine bone were obtained and used as control group (C‐group).ResultsMild to moderate immunohistochemical expression of native granular BMP‐4 was present in 56.8% (31.0% AB‐group, 22.4% M‐group, and 3.4% C‐group) (p = 0.000, chi‐square) of the specimens analyzed. BMP‐4 expression was primarily located in the cytoplasm of osteoblasts, osteoclasts, and epithelial cells of the schneiderian membrane. Whereas significant differences were observed in the proportion of mineralized tissue and cellularity between sinuses grafted with anorganic bovine bone, allograft, or nongrafted sinuses, there were no statistically significant differences in the cellular expression of BMP‐4 among groups.ConclusionOur findings suggest that the native expression of BMP‐4 appears to be associated with normal bone homeostasis and reparation in grafted and nongrafted maxillary sites.
Anatomical Considerations on the Alveolar Antral Artery as Related to the Sinus Augmentation Surgical Procedure
Authors: Valente Nicola Alberto 
Published: May 2015

AbstractBackgroundThe alveolar antral artery (AAA) is a vascular structure that often passes through the area of lateral window opening during sinus augmentation and can reach dimensions that, if the vessel is severed, can represent a serious complication of the surgical procedure.PurposeWith this narrative review, we aimed at summarizing the results obtained from all the studies that analyzed the variability in anatomical position and dimension of the AAA in order to give the clinician a reference when planning for a sinus augmentation surgery.Materials and MethodsA search of available literature was conducted using electronic databases (PubMed and Medline) and manual searching.ResultsDetection rate of AAA on cone beam computerized tomography (CBCT) is variable and may depend upon the experience of the clinician. The course of the vessel is most frequently intraosseous, and its diameter, despite being smaller than 1 mm in most of the cases, can have a high incidence of diameters between 1 mm and 2 mm. Mean distances of the AAA from alveolar crest and sinus floor range from 11.25 mm to 26.90 mm and 5.80 mm to 10.40 mm.ConclusionsAnatomical variants of the AAA that may increase the risk of severe intraoperatory bleeding are frequent and must be detected by the clinician implementing the use of the CBCT.