bluuebunny/crossref_metadata_2025_split huggingface dataset:
Model for the Study of Drug Hypersensitivity Based on Bucilamine and the HLA-DRB1*08:02 Allele in Colombian Amerindian Populations
Authors: Lozano Carlos Hernando Parga , Guerrero Nohemí Esther Santodomingo 
Published: August 2024

Backgrounds: Allergic diseases and hypersensitivity reactions are common disorders that in turn consist of an extensive genetic component in which the molecules of the Major Histocompatibility Complex (MHC) are included, which have certain alleles associated with the development of hypersensitivity to certain drugs, among which is the allele HLA-DRB1 * 08: 02 as a predisposing factor of hypersensitivity to Bucillamine; this drug is the starting point for the study of the relationship between hypersensitivity reactions to medications and the expression of certain alleles of MHC.

Objective: Find the relationship between hypersensitivity to the drug and the expression of the specific allele in Amerindian populations of the Sierra Nevada de Santa Marta and in turn suggest the application of the methodological model proposed in similar studies that seek to relate drug allergies with specific HLA alleles.

Methods: A systematic search of information was carried out in the Sience, ScienceDirect, Elsevier and Pubmed databases, the frequencies obtained were tabulated and organized according to their expression to be analyzed with the MEGA7 software.

Results: A significant frequency of the HLA-DRB1 * 08: 02 allele was found in the Ijka (61.7%), Arhuaco (41.5%), Kogi (17.9%) and Arsario (15%).

Conclusion: A cautious use of Bucillamine and structurally similar drugs it’s recommended in susceptible Amerindian populations, at the same time the application of the proposed model it’s recommended for the study of different drugs that could trigger an allergic reaction based on HLA’s allele expression.
Antecedents of Destination Image and Revisitation Intentions Post COVID-19: a Study in Indonesia
Authors: Daru Radityo Suksmaneng , Hudaya Syarifah , Trichayadinata Irsan , Hariyadi Sugeng 
Published: August 2024

Objective: This research aims to explore the dynamics of destination image on the tourism landscape of Berau Regency, East Kalimantan Province, focusing on cultural, socio-economic, and environmental dimensions. A survey was conducted from November 2022 to June 2023

Theoretical Framework: consumer behavior theory, tourism, destination image, cultural image, socio-economic image, environmental image and tourist satisfaction

Method: The survey was conducted from November 2022 to June 2023 by collecting data from 135 tourists in Indonesia through purposive random sampling. Variance-based Structural Equation Modeling (SEM) was used to analyze the data.

Results and Discussion: These results emphasize the important role of cultural preservation, socio-economic development, and environmental management in optimizing tourist experiences and promoting destination sustainability, offering valuable insights for stakeholders and policymakers in destination management and tourism policymaking.

Research Implications: This research aims to explore the dynamics of destination image in the tourism landscape of Berau Regency, East Kalimantan Province, with a focus on cultural, socio-economic, and environmental dimensions.

Originality/Value: these findings offer valuable insights for stakeholders and policymakers to optimize tourist experiences, promote destination sustainability, and foster the growth of Berau Regency's tourism industry post-pandemic.

Keywords: Destination Image Cultural Image, Socio-Economic Image, Environmental Image, Memorable Tourism Experience, Tourist Satisfaction, Interest in Returning, Tourism.
Challenges in Adopting Agile Methodologies in the Software Engineering Processes Management: a Literature Review
Authors: Sena Jefferson Wanderson Pereira de , Oliveira Sandro Ronaldo Bezerra 
Published: August 2024

Objective: To identify and select the main challenges in adopting agile methodologies in the software engineering processes management, that is, to analyze the most recurring challenges involving the application of agile methodologies in organizational environments.

Theoretical Framework: Software Development is marked by a dynamic environment in constant change, where organizations must experiment with new values, manifested in flexibility, adaptation, intelligence, innovation and proactivity, using innovative tools, as conditions to become efficient and competitive.

Method: The research was conducted based on bibliographical review, whose strategy was the analysis of a group of authors who constituted the theoretical framework to substantiate and explain the categories of this study, centered on agile methodologies.

Results and Discussion: The results revealed that organizations encounter obstacles of different natures to implement agile methodologies in their environment, making project development difficult, thus not having the changes considered with good receptivity among employees, given the ingrained values and culture, becoming challenges for the organization.

Implications of the Research: Given this evidence, it is concluded that organizational culture has as its primary factor resistance to change, as being the organization's main challenge for the acceptance and implementation of agile methodologies, indicating that there is no compatibility between organizational culture and agile methodologies.

Originality/Value: This study contributes to identifying factors that become challenges to the successful implementation of agile methodologies in organizations, such as changes in organizational culture.
Educational Games based on the Contextual Teaching Learning (CTL) Approach: Increasing Motivation & Critical Thinking for Students in Riau Province
Authors: Yuliastrin Adisti , Vebrianto Rian , Thahir Musa , Berlian Mery , Permana Niki Dian 
Published: August 2024

Purpose: This research aims to develop interactive multimedia based on educational games using the Contextual Teaching Learning (CTL) approach to enhance students' learning motivation and critical thinking abilities.

Theoretical Reference: Employing the Borg and Gall development model, the study follows stages of identifying potential and problems, data collection, product design, design validation, design revision, product testing, and product revision.

Method: The game design meticulously considers content, language, presentation, graphics, and programming aspects.

Results and Conclusion: Evaluation results demonstrate that the game is of good quality, effectively supports the CTL approach, and has received positive user feedback. Suggested improvements include enhancements in language and sound, use of animated images, additional material, and mobile use considerations.

Implications of Research: The research indicates that further development could make the educational game a valuable tool for increasing student motivation and critical thinking across various educational contexts.

Originality/Value: The integration of the CTL approach within an educational game, validated through a systematic model, highlights its originality and potential value in improving educational outcomes.
Remote Sensing Applied to Pasture Monitoring: A Review
Authors: Hott Marcos Cicarini , Andrad Ricardo Guimarães , D’Oliveira Pérsio Sandir , Motta Matheus Bertolino , Rocha Wadson Sebastião Duarte da , Magalhães Junior Walter Coelho Pereira de 
Published: August 2024

Objective: The goal of this study was to review the results obtained by various authors for large-scale pasture monitoring via remote sensing; to monitor the development and degradation conditions of pastures according to case studies; and to analyze data, images, and Geographic Information System (GIS) procedures in relevant works. Theoretical Framework: In this topic, the principles that guided the literature review are presented, including a discussion of the search for remote sensing results related to pastures in large geographical areas, and case studies in works that denote the technological potential from field sampling and results worldwide are also presented. Method: Research methods associated with different themes, keywords, and regions were adopted to identify results from research in the area of remote sensing applied to surveying the conditions of pastures in the different typologies in the studied regions. Results and Discussion: The literature review in this study highlights the advances and methodologies developed for the evaluation of pasture conditions and mapping, from which it was possible to observe the stage of degradation of this vegetation, which is essential for agricultural production. Research Implications: The potential of using remote sensing materials and mechanisms for pasture assessment, mapping areas in stages of degradation and identifying vegetation vigor is highly valuable in large-scale pasture management. The presented literature indicates that pasture vegetation varies greatly according to geographic region, indicating great complexity in deriving its phenological conditions and showing that field campaigns are essential for the description and establishment of a relationship between the foliar canopy and sensor response. Originality/Value: This literature review addresses large-scale remote sensing surveys of pastures, contributing to research on the conditions of this vegetation. The bibliography presented in this review can support studies on mapping the pasture degradation process through remote sensing images and data.
Technical and Economica Feasibility of Photovoltaic Tiles Applies to a Single-Family Residence in Belo Horizonte-MG
Authors: Horta Ricardo Augusto dos Santos , Lima Weslley Eunathan Fernandes , Pacheco Tiago de Sousa , Villela Luciana Silva , Oliveira Raquel Diniz , Penna Rodrigo de Mello Morado 
Published: August 2024

Objective: The objective of this study is to verify whether photovoltaic tile technology presents technical and economic feasibility to be implemented in a single-family residence located in Belo Horizonte-MG.

Theoretical framework: Through the photoelectric effect, photovoltaic tiles directly convert solar energy into electrical energy in a static, silent, non-polluting and renewable way. In this system, photons, energy-carrying particles present in sunlight, fall on a surface composed of photovoltaic cells (made of semiconductor material). At the ends of the semiconductor material, an electrical potential difference appears, responsible for setting the electrons in the structure in motion, producing electric current.

Methodology: The methodology adopted for this research consists of simulating the energy consumption of a 77m2 residential building, consisting of 3 members. The tile and photovoltaic panel systems were designed to meet the energy demands of this building.

Results and discussion: The results indicated that both systems present technical feasibility for their implementation, since the technologies demonstrated that they are capable of satisfying 100% of energy needs. However, from an economic point of view, only photovoltaic modules were viable.

Originality/value: This work makes a contribution to the literature by analyzing a technology that is still little known in the energy market.

Implications of the research: The relevance and value of this research are evidenced by the fact that photovoltaic tiles are a sustainable alternative to generate clean energy and reduce greenhouse gas emissions, which can contribute to the diversification of the Brazilian energy matrix and mitigation of impacts. of civil construction.
Psychological, Subjective and Social Well-Being of Victims of The Armed Conflict in The Municipality of Chalán – Sucre (Colombia)
Authors: Henrriquez Cindy Hernández , Hernández Patricia Mendivil , Pinillos María Alexandra Morales , Chamorro Mónica Herazo , Sánchez Eduardo González , Dominguez Marelis Gomez 
Published: August 2024

Objective: To describe the level of psychological, social and subjective well-being in victims of the armed conflict in the municipality of Chalán.

Theoretical Framework: Mental health includes psychological, subjective and social well-being. Psychological well-being encompasses the satisfaction and optimal functioning of the individual. Subjective well-being refers to the perception of quality of life and personal satisfaction. Social well-being assesses the perception of social functioning and social context, including social integration and contribution.

Method: A quantitative approach was adopted with a descriptive non-experimental cross-sectional cohort design. The participants were 75 victims of the armed conflict. The following scales were used: Ryff's Psychological Well-Being, Keyes' Social Well-Being and Sánchez Cánovas' Subjective Psychological Well-Being.

Results and Discussion: 56% of the participants reflect a deficit in their psychological well-being, 36% are at a standard level and only 8% are at a high level, in line with research on victims of the armed conflict in Colombia. The 46.6% evaluate their subjective well-being negatively, while 57.3% evaluate it positively, highlighting the complex interaction between traumatic experiences and current satisfaction. 88% present a deficit in their social well-being.

Research implications: The results have direct implications for the formulation of policies and intervention programs aimed at improving the comprehensive well-being of victims of the armed conflict.

Originality/value: It lays the foundation for future research and practices focused on similar contexts, expanding knowledge and improving interventions in conflict and post-conflict situations globally.
Communication Skills and Empowerment of Rural Women
Authors: Flores-Mamani Emilio , Machaca-Machaca Ruth- Delia , Flores-Yapuchura Ányela-Yésica , Tapia-Espinoza Pedro- Basilio , Rolando- Esteban Rodríguez-Huamani , Edwin- Abdon Quispe-Cansaya 
Published: August 2024

Objective: To determine the relationship between communication skills and the empowerment of women farmers located in the Puno region, Peru.

Theoretical Framework: The theoretical basis focuses on communication skills and women's empowerment. Communication skills refer to an individual's ability to express their thoughts, needs, feelings, desires, and concerns using oral and written language, which serve as tools to facilitate interaction among participants involved in communication. Women's empowerment is the process through which women increase their capacity to shape their own lives and environments, manifested in different ways: a sense of security, economic participation, political involvement, leadership, and decision-making.

Methodology: The methodology is based on a quantitative correlational research approach, with a non-experimental and cross-sectional design. The sample was census-based and consisted of 40 women leaders representing the rural communities of the Human Rights and Environment Association.

Results: There is a moderately positive and significant correlation between communication skills and women's empowerment (r = 0.53), with a p-value < 0.05. This indicates that as communication skills develop, women's empowerment improves, giving them greater opportunities to participate in politics, the economy, and decision-making, which contributes to improving their family and local lifestyle.
Improvement Proposal for Enhancing the Role of Dentists Within the Family Health Strategy Workframe
Authors: Cruz Tirza de Oliveira , Chesani Fabiola Hermes , Gouvea Pollyana Bortholazzi 
Published: August 2024

Objective: This research aimed to develop an improvement proposal for enhancing the role of dentists within the Family Health Strategy (FHS) framework in a municipality in the Vale do Itajaí region.

Method: The methodology adopted in this study comprised exploratory, descriptive, and qualitative research. Data collection took place in a municipality with 18 primary health care units. The participants were 10 dentists working in these units, who responded to semi-structured interviews.

Results and Discussion: Data were consolidated through content analysis, revealing four categories for discussion: 1) management and its implications on dental practice; 2) strategic planning as a tool for dental practice-related actions; 3) the impact of the COVID-19 pandemic and post-pandemic on the work process of dentists; and 4) the importance of more dental professionals within the FHS.

Research Implications: the oral health management model of the study municipality was not well defined, there is a lack of epidemiological data, health indicators and the territorialization process in the territory assigned to each UBS, difficulty in communication and understanding as required of the coordinator in oral health.

Originality/Value: The proposed flowchart for improving the dentist's role within the Family Health Strategy represents innovation in Primary Care.
Inclusive Cities for Visually Impaired People
Authors: Santos Deborah Macedo dos , Pontes Thiago Bessa , Landim Camila Bandeira Pinheiro 
Published: August 2024

Objective: The objective of this study is to to present a literature review and its evolution regarding how elements of city architecture can contribute to the inclusion of the visually impaired and the most appropriate way to reproduce it, specifically in the context of Brazil.

Theoretical Framework: The urban organization of a city can either contribute to or hinder human interactions, social inclusion, and the autonomy of people with disabilities. However, for a long time, cities were not planned to accommodate diversity, becoming even a segregating space for some minorities, such as the visually impaired.

Method: The methodology adopted for this research includes the review and discussion of books, articles, specialized virtual pages, and pertinent legislation.

Results and Discussion: The results obtained revealed that urban orientation elements for the visually impaired lack standardization, making them a hindrance to their perception.

Research Implications: Future work needs to invest in the research for the standardization of tactile maps and floors, also incorporating new technologies.

Originality/Value: This study contributes to the literature by discussing city architecture from the perspective of the visually impaired, highlighting practical contributions for better territorial performance for this specific population.
Implementation and Linearization of a Coupled Panel and Vortex Particle Method in State-Space Form
Authors: Hussien Hussien A. A. H. , Cocco Alessandro , Saetti Umberto 
Published: August 2024

This paper describes the implementation and linearization of a coupled panel and vortex particle method in a state-variable form. More specifically, the coupled panel and vortex particle dynamics are formulated as a nonlinear system of ordinary differential equations in first-order form to be self-contained and inherently linearizable. Linearization of this coupled panel and vortex particle method is demonstrated via finite differencing and a novel analytical linearization technique to yield a linear time-invariant representation. The code is implemented in MATLAB® and validated against an open-source aerodynamic solver for a fixed wing in both stationary and unsteady conditions. The linearized models are verified against the nonlinear dynamics both in the time and frequency domains. Linearized models accurately represent the wake dynamics about the equilibrium condition for moderate amplitude inputs and for input frequencies covering the typical frequency range of flight dynamics and flight controls, i.e., 0.3–30 rad/s. Analytical linearization is shown to abate the cost of linearization over perturbation methods by [Formula: see text], where [Formula: see text] is the total number of states of the system. Linearized models of the coupled panel and vortex particle dynamics have applications in the flight dynamics of both fixed- and rotary-wing vehicles, where these dynamics can be used to augment the rigid-body dynamics. The coupled rigid-body and wake dynamics can be leveraged to assess the stability, response characteristics, and handling qualities of vehicles experiencing aerodynamic interactions between rotors, wings, and/or obstacles.
Scaling Laws for Deployable Mesh Reflector Antennas
Authors: Suh Jong-Eun , Dassanayake Sahangi P. , Thomson Mark W. , Pellegrino Sergio 
Published: August 2024

This paper begins with the formulation of a general, rapid design method for deployable mesh reflector antennas based on the AstroMesh architecture. This method is then used to obtain estimates of the total mass, stowed envelope size, and fundamental natural frequency of vibration for antennas with a range of aperture diameters and focal lengths, assuming an operational radio frequency of 10 GHz. A study of the scaling trends of this reflector design shows that the distribution of prestress in the inner tension structure has a major impact on the mass of the outer perimeter truss. Based on this result, a prestress optimization problem to design reflectors of minimum mass is formulated, and analytical scaling laws are obtained for the mass, stowed envelope, and natural frequency of optimally prestressed reflectors with aperture diameters up to 200 m. It is then shown that aperture diameters of 70–100 m are at the limit of launchers that are currently available or under development. A semianalytical homogenization model that accurately estimates the fundamental natural frequencies for batten-supported and free-free boundary conditions is also presented.
Effect of Tripping and Domain Width on Transonic Buffet on Periodic NASA-CRM Airfoils
Authors: Lusher David J. , Sansica Andrea , Hashimoto Atsushi 
Published: August 2024

Transonic buffet is an instability characterized by shock oscillations and separated boundary layers. High-fidelity simulations have typically been limited to narrow domains to be computationally feasible, overly constraining the flow and introducing modeling errors. Depending on the boundary-layer state upstream of the interaction, different buffet features are observed. High-fidelity simulations (implicit large-eddy simulation) were performed on the periodic (infinite) NASA-CRM wing at a moderate Reynolds number to assess the sensitivity of the two-dimensional transonic buffet to boundary-layer state and domain width. Simulations were cross-validated against low-fidelity Reynolds-averaged Navier–Stokes (RANS)/unsteady RANS and global stability analysis, and excellent agreement was found near the onset. By varying the boundary-layer tripping amplitude, laminar, transitional, and turbulent buffet interactions were obtained. All cases consisted of a single shock and low-frequency oscillations [Formula: see text]. The transitional interaction also exhibited reduced shock movement, a 15% increase in [Formula: see text], and energy content at higher frequencies [Formula: see text]. Spanwise domain studies showed sensitivity at the shock location and near the trailing edge. We conclude that the span width must be greater than the trailing-edge boundary-layer thickness to obtain span-independent solutions. For largely separated cases, the sensitivity to span width increased, and variations across the span were observed. This was found to be associated with a loss of two-dimensionality in the flow.