bluuebunny/crossref_metadata_2025_split huggingface dataset:
القضايا البلاغية في شرح ابن عقيل على ألفية ابن مالك وأثرها في توجيه المعاني والدلالات القرآنية
Authors: Abedalaziz Maryam , Al-Haj Thabet Abu , Yusoff M. Y. Zulkifli Mohd 
Published: August 2024

Abstract
The aim of this research is to uncover the rhetorical issues in Ibn Aqīl’s explanation of Ibn Malik’s Alfiyyah and their impact on emphasizing the rhetorical significance of the text through the evidence cited in the explanation of Alfiyyah. It explores the extent to which this contributes to understanding the words of Allah Almighty in accordance with their indications and purposes. Ibn Aqīl referenced 264 instances from the Quran in his explanation of Alfiyyah, 164 of which contain rhetorical issues, such as conciseness, anticipation, delay, distinction, connection, definition, negation, indications of meaningful letters, differences in adverbial clauses, and others. The researchers followed a dual methodology combining examination and analysis. They collected Quranic evidence within Ibn Aqīl’s explanation, targeting those associated with rhetorical issues for study, analysis, and deriving benefits and implications. The research concluded that Ibn Aqīl’s explanation contains the fundamentals of rhetoric alongside the rules of grammar. It serves as a foundational rhetorical and grammatical basis related to the Quran, deriving inspiration and relying upon it.
Fairyland-scape: Locus of Retelling and Remembering Ecocentric Tales
Authors: Gülüm Erol 
Published: August 2024

Abstract
This article explores how and why (re)constructions of Fairyland in Earthland can create fairyland-scapes that serve as sites of retelling and remembering ecocentric tales. To conceptualise and theorise the notion of fairyland-scape, the article employs folkloric memory as an approach, fairyland ecology as a method, and fairyland ecosystem as a model. To demonstrate and analyse the various forms and samples of fairyland-scape in practice, the article also examines the interplay between The Grimm Brothers’ Kinder- und Hausmärchen (Children’s and Household Tales) and Die Deutsche Märchenstraße (The German Fairy Tale Route) as a case study.
Voluntary nicotine consumption and reward in a subset of diversity outbred founder strains
Authors: Rahman Yumna , Buzzi Belle , Rogers Walker , Miles Michael F , Damaj M Imad 
Published: August 2024

Background: Nicotine is largely responsible for the initiation and maintenance of tobacco dependence and contributes to a global health problem. Aims: This study characterizes nicotine oral consumption and preference in male and female mice of several Diversity Outbred (DO) founder strains: C57BL/6J, A/J, 129S1/SvImJ, PWK/PhJ, NOD/ShiLtJ, and CAST/EiJ. It assesses the impact of nicotine concentration on intake and preference, the potential interaction of strain with sex, and estimates the degree of heritable variation in nicotine consumption. Methods: Two-bottle choice oral self-administration paradigm was used to assess nicotine intake, nicotine preference, and total fluid intake in male and female mice of each strain in a concentration-response manner. A conditioned place preference (CPP) test was performed to evaluate the rewarding and aversive effects of nicotine in certain strains after systemic administration of the drug. Results: The highest nicotine-consuming strain was found to be 129S1/SvlmJ, and the lowest nicotine-consuming strain was A/J. Strain differences in nicotine intake were not due to differences in bitter and sweet tastes as shown in the saccharine and quinine two-bottle choice tests. A/J strain showed no significant CPP for nicotine while the 129S1/SvImJ strain showed a significant CPP for nicotine and a higher preference when compared to the C57BL/6J strain. Heritability estimates of nicotine intake were sex dependent and concentration dependent. Conclusions: Data support that nicotine consumption patterns are heritable with an influence of genotype in a voluntary oral self-administration paradigm. Results pave the way for future studies with the highly recombinant DO mice that might lead to the identification of novel genetic loci and genes influencing nicotine consumption.
Correlation between human papillomavirus protein expression and clinicopathological features in oral squamous cell carcinoma
Authors: Wang Lin , Jiang Nian , Lee Chen Chijen 
Published: August 2024

Objective Given the implications of concurrent human papilloma viral infection (HPV) in the prognostic course and implications on therapeutic approached of patients with oral squamous cell carcinoma (OSCC), we seek to investigate the implications that P16 expression has on the clinical course and pathological appearance of patients with OSCC and concurrent infection. Methods Using S-P immunohistochemistry, we examined the expression of P16 and Ki67 in 460 patients with OSCC. We compared the expression of the protein between the tumor cells and normal epithelial mucosa within the same patient. The clinical and pathological characteristics (including gender, age, histological grade, lymph node metastasis, clinical stage, clinical recurrence, tumor diameter, Ki67 proliferation index) were analyzed by stratification statistically. Results In total 460 cases of OSCC were identified and expression of P16 was significantly higher in the OSCC group compared to the normal mucosal epithelial group (X2 = 60.545, p = .000). There also appear to be a gender predilection as the expression was higher in females compared to males (0.218 vs. 0.144, X2 = 3.921, p = .048). Younger age also appears to be a predictive factor as those under 35 years old had higher expression of the protein compared to those over 35 years old (0.294 vs. 0.157, X2 = 4.230, p = .040). P16 positivity showed a significant positive correlation with histologic grade (X2 = 4.114, p = .043). In addition, the positive rate of P16 was higher in patients with ki67 over 85% (0.455 vs. 0.160, X2 = 6.667, p = .023). Conclusion OSCC with HPV infection tends to occur more frequently in female patients and those under 35 years of age. HPV infection with expression of the P16 and ki67 protein may promote the proliferation and growth of OSCC at a higher frequency.
Detection and classification of spongy tissue disorder in mango fruit during ripening by using visible-near infrared spectroscopy and multivariate analysis
Authors: Kiran Patil R , Jadhav Parth , Avinash G , Aradwad Pramod , TV Arunkumar , Bhardwaj Rakesh , Parray Roaf A 
Published: August 2024

The esteemed Alphonso mango, cherished in India for its taste, saffron color, texture, and extended shelf life, holds global commercial appeal. Unfortunately, the prevalent spongy tissue disorder in Alphonso mangoes results in a soft and corky texture, with up to 30% of mangoes within a single batch affected. This issue leads to outright rejection during export due to delayed disorder identification. The current assessment method involves destructive sampling, causing substantial fruit loss, and lacks assurance for overall batch quality. In light of the mentioned challenges, this current study focuses on utilizing visible-near infrared (Vis-NIR) spectroscopy as a non-invasive method to assess the internal quality of mangoes. It also enables innovative classification models for automated binary categorization (healthy vs spongy tissue-affected). Through preprocessing and principal component analysis of spectral reflectance data, wavelength ranges of 670–750 nm, 900–970 nm, and 1100–1170 nm were identified for distinguishing healthy and damaged mangoes. Soft independent modelling of class analogy (SIMCA) modelling is a novel approach that can be used to classify mango into healthy and spongy tissue-affected categories for better postharvest management. The accuracy of SIMCA models for classifying mangoes into healthy and spongy tissue-affected classes was highest in the wavelength regions of 670–750 nm and 900–970 nm, being 94.4% and 96.7%, respectively. The spectral reflectance between wavelength region 650–970 nm gave significant and visible differentiation between all stages of spongy tissue, that is, mild, medium, and severe. Furthermore, the application of Vis-NIR spectroscopy alongside SIMCA modelling offers a viable avenue for examining internal abnormalities resulting from diseases or injuries in fruits, broadening its utility for diverse inspection needs.
Establishment and Validation of Prognostic Nomograms for Patients with Metastatic Pulmonary Large Cell Neuroendocrine Carcinoma
Authors: Chen Xiaoyun , Lai Xingyue , Huang Yedong , Deng Chaosheng 
Published: August 2024

Purpose Metastatic pulmonary large cell neuroendocrine carcinoma (LCNEC) is an aggressive cancer with generally poor outcomes. Effective methods for predicting survival in patients with metastatic LCNEC are needed. This study aimed to identify independent survival predictors and develop nomograms for predicting survival in patients with metastatic LCNEC. Patients and Methods We conducted a retrospective analysis using the Surveillance, Epidemiology, and End Results (SEER) database, identifying patients with metastatic LCNEC diagnosed between 2010 and 2017. To find independent predictors of cancer-specific survival (CSS), we performed Cox regression analysis. A nomogram was developed to predict the 6-, 12-, and 18-month CSS rates of patients with metastatic LCNEC. The concordance index (C-index), area under the receiver operating characteristic (ROC) curves (AUC), and calibration curves were adopted with the aim of assessing whether the model can be discriminative and reliable. Decision curve analyses (DCAs) were used to assess the model’s utility and benefits from a clinical perspective. Results This study enrolled a total of 616 patients, of whom 432 were allocated to the training cohort and 184 to the validation cohort. Age, T staging, N staging, metastatic sites, radiotherapy, and chemotherapy were identified as independent prognostic factors for patients with metastatic LCNEC based on multivariable Cox regression analysis results. The nomogram showed strong performance with C-index values of 0.733 and 0.728 for the training and validation cohorts, respectively. ROC curves indicated good predictive performance of the model, with AUC values of 0.796, 0.735, and 0.736 for predicting the 6-, 12-, and 18-month CSS rates of patients with metastatic LCNEC in the training cohort, and 0.795, 0.801, and 0.780 in the validation cohort, respectively. Calibration curves and DCAs confirmed the nomogram’s reliability and clinical utility. Conclusion The new nomogram was developed for predicting CSS in patients with metastatic LCNEC, providing personalized risk evaluation and aiding clinical decision-making.
Differences in Interfacility Transfer from Emergency Department and Inpatient Services for Inpatient Neurologic Care
Authors: Shah Maulik P. , Douglas Anne G. , Sauer Brian M. , Richie Megan B. , Douglas Vanja C. , Josephson S. Andrew , Guterman Elan L. 
Published: August 2024

Introduction Interhospital transfer is an important mechanism for improving access to specialized neurologic care but there are large gaps in our understanding of interhospital transfer for the management of non-stroke-related neurologic disease. Methods This observational study included consecutive patients admitted to an adult academic general neurology service via interhospital transfer from July 1, 2015 to July 1, 2017. Characteristics of the referring hospital and transferred patients were obtained through the American Hospital Association Directory, a hospital transfer database maintained by the accepting hospital, and the electronic medical record. The analyses used descriptive statistics to examine the cohort overall and compare characteristics of patients transferred from an emergency department and inpatient service. Results 504 patients were admitted via interhospital transfer during the study period. Of these, 395 patients (78.4%) were transferred because the referring hospital lacked capability, and 139 patients (27.6%) were transferred from an emergency department as opposed to inpatient service. Seizures was the most common diagnosis (23.8%). Patients who were transferred from an emergency department had a higher proportion covered by Medicaid (44.6%) than those transferred from an inpatient service (28.8%) and had a shorter median length of stay (3 days; IQR 2-7 vs 7 days; IQR 4-12). Conclusions The majority of observed interhospital non-stroke neurologic transfers occurred to improve access to specialized neurological care for patients, though patients transferred from the ED, as opposed to an inpatient service, had lower health care utilization, and this will be important to consider when developing systems of care and in future research.
The Impact of the COVID-19 Pandemic on One-Year Mortality in Geriatric Hip Fracture: A Retrospective Cohort Study
Authors: Selçuk Eşref , Erem Murat , Selçuk Emine Gökçen , Mercan Oğuz 
Published: August 2024

Introduction The COVID-19 pandemic has profoundly impacted global healthcare systems, necessitating substantial shifts in patient care strategies. The pandemic’s onset led to drastic operational changes in hospitals, including reduced bed capacity and staffing levels, which could have further influenced the mortality outcomes for geriatric patients. The study aimed to assess the impact of the COVID-19 pandemic on 1-year mortality rates of surgically treated geriatric hip fractures. Methods This retrospective, single-center cohort study included 346 participants aged 65 and above who underwent surgical treatment for hip fractures. We compared mortality rates between the pre-COVID and COVID eras. Data included demographics, treatment, complications, and COVID-19 status. The independent samples t test and Chi-square tests (or Fisher’s exact test) were used for comparisons for era cohorts. Survival probabilities were assessed using Kaplan-Meier, while multivariate analysis identified mortality predictors. Results 175 patients were included in the pre-COVID era, and 171 patients were included in the COVID era. During the COVID era, the 30-day mortality rate was 11.7% (compared to 13.7% in the pre-COVID era, p = 0.573), and the 1-year mortality rate was 43.9% (compared to 49.1% in the pre-COVID era, p = 0.325). The overall 1-year mortality rate was 46.5%. Patients who underwent surgery within 48 hours had a higher 1-year survival rate (60.5%) compared to those with delayed surgery (51.2%), p = 0.031. Additionally, patients not admitted to the ICU had a higher 1-year survival rate (74.7%) than those who were admitted (44.9%), p < 0.001. 70.1% of the total deaths occurred within the first 90 days. Conclusion Elderly patients with hip fractures experienced high mortality rates before and during the pandemic. This study demonstrates that the 1-year mortality rates of geriatric hip fractures were not significantly affected by the pandemic. The findings emphasize the importance of pandemic preparedness and prompt surgeries and attentive ICU care in reducing mortality rates.
Kinematic Modeling of Pitch Velocity in High School and Professional Baseball Pitchers: Comparisons With the Literature
Authors: Manzi Joseph E. , Dowling Brittany , Wang Zhaorui , Sudah Suleiman Y. , Moran Jay , Chen Frank R. , Estrada Jennifer A. , Nicholson Allen , Ciccotti Michael C. , Ruzbarsky Joseph J. , Dines Joshua S. 
Published: August 2024

Background: Kinematic parameters predictive of pitch velocity have been evaluated in adolescent and collegiate baseball pitchers; however, they have not been established for high school or professional pitchers. Purpose: To create multiregression models using anthropometric and kinematics features most predictive for pitch velocity in high school and professional pitchers and compare them with prior multiregression models evaluating other playing levels. Study Design: Descriptive laboratory study. Methods: High school (n = 59) and professional (n = 337) baseball pitchers threw 8 to 12 fastballs while being evaluated with 3-dimensional motion capture (480 Hz). Using anthropometric and kinematic variables, multiregression models for pitch velocity were created for each group. A systematic review was conducted to determine previous studies that established kinematic models for ball velocity in youth, high school, and collegiate pitchers. Results: Leg length was predictive of pitch velocity for high school and professional pitchers ( P < .001 for both). When compared with previously established models for pitch velocity, almost all groups were distinct from one another when assessing age ( Pmaximum < .001), weight ( Pmax = .0095), and pitch velocity ( Pmax < .001). Stride length was a significant predictor for the youth/high school pitchers, as well as the current study's high school and professional pitchers ( P < .001 for all). Maximal shoulder external rotation (collegiate: P = .001; professional: P < .001) and maximal elbow extension velocity (high school/collegiate: P = .024; collegiate: P < .001; professional: P = .006) were shared predictors for the collegiate and current study's professional group multiregression models. Trunk flexion at ball release was a commonly shared predictor in the youth/high school ( P = .04), high school/collegiate ( P = .003), collegiate ( P < .001), and the current study's professional group ( P < .001). Conclusion: Youth, high school, collegiate, and professional pitchers had unique, predictive kinematic and anthropometric features predictive of pitch velocity. Leg length, stride length, trunk flexion at ball release, and maximal shoulder external rotation were predictive features that were shared between playing levels. Clinical Relevance: Coaches, clinicians, scouts, and pitchers can consider both the unique and the shared predictive features at each playing level when attempting to maximize pitch velocity.
General practitioners’ perspectives on lifestyle interventions for cognitive preservation in dementia prevention
Authors: Kappe Josefine , Wittmann Felix , Luppa Melanie , Cardona Maria Isabel , Weise Solveign , Fuchs Stephan , Kosilek Robert Philipp , Sanftenberg Linda , Brettschneider Christian , Döhring Juliane , Escales Catharina , Czock David , Wiese Birgitt , Thyrian Jochen René , Hoffmann Wolfgang , Frese Thomas , Gensichen Jochen , König Hans-Helmut , Kaduszkiewicz Hanna , Riedel-Heller Steffi Gerlinde 
Published: August 2024

Abstract
Background
General practitioners (GPs) play a crucial role in identifying cognitive impairment and dementia and providing post-diagnostic care. This study investigates (1) how promising GP consider lifestyle changes to maintain cognitive performance in general, (2) GP beliefs about the power of modifiable health and lifestyle factors to maintain cognitive performance, and (3) whether those beliefs vary by GP age.

Methods
As part of the AgeWell.de trial, GPs (n = 72) completed a process evaluation questionnaire assessing their perspectives on lifestyle changes to preserve cognitive performance in elderly patients. In greater detail, their perceived efficacy of established risk and protective factors was investigated using a 5-point Likert scale. Descriptive statistical analyses were performed for research question (1) and (2). Spearman´s rank correlations and ordinal logistic regressions were used to answer research question (3). All results were interpreted exploratively.

Results
GPs rated the overall chance of lifestyle changes maintaining cognitive performance quite neutral with a median score of 3.0 (IQR = 2.0). They rated the efficacy of all the modifiable health and lifestyle factors high, with increase in physical and social activity ((Mdn = 5.0, IQR = 1.0) receiving the highest ratings with the narrowest range. Spearman's rank correlation indicated a significant positive relationship between age and the belief in “Optimization of nutrition” for preventing cognitive decline and dementia (ρ = .255, p = .041). However, ordinal logistic regressions showed no significant relationships between age and GP ratings of lifestyle change efficacy.

Conclusion
These findings highlight the positive perception of GPs on the efficacy of modifiable health and lifestyle factors for preventing cognitive decline and dementia.

Trial registration
The AgeWell.de trial is registered in the German Clinical Trials Register (DRKS; trial identifier: DRKS00013555, Registration Date 07 December 2017).
Interrelationship between subjective wellbeing and health
Authors: Mathentamo Qaqambile , Lawana Nozuko , Hlafa Besuthu 
Published: August 2024

Abstract
Background
Subjective wellbeing (SWB) and health are important facets of any person’s life, and they tend to influence each other. This importance is reflected in the vastness of literature aiming to explore this association. However, most of this literature is based on sampling national population which may present different population characteristics to those of a province. Thus, the paper aims to investigate if the association between perceived health and SWB is moderated by population characteristics at a provincial level. We intend to add value to subjective wellbeing and health literature by reviewing the relationship between SWB and health in the Eastern Cape stratified by age, gender, rural and urban and different income classifications.

Methods
Different population characteristics tend to associate to subjective wellbeing and health differently, therefore influencing how these two variables influence each other. Thus, the paper aims to investigate if the association between perceived health and SWB is moderated by population characteristics at a provincial level. Utilising the South African National Income Dynamics Survey from 2008 to 2017, this study examined the relationship between subjective wellbeing and health using a random effects model stratified according to aforementioned population characteristics.

Results
A better perceived health status is associated with higher subjective wellbeing. A better subjective wellbeing is also associated with a higher health status. Determinants of subjective wellbeing and health associate with these variables differently besides income and employment which led to higher subjective wellbeing and health. Health associates to subjective wellbeing different across populations characteristics.

Conclusion
Subjective wellbeing and health are interdependent as reflected in the World Health Organisation (WHO) and United Nation (UN) statements. Higher income and level of education and being employed is associated with both higher SWB and health. Therefore, improving these economic outcomes maybe associated with an improvement in well-being and health as desired by WHO and UN. Provinces differ, and different population characteristics tend to associate with subjective wellbeing and health differently, therefore influencing how these two variables influence each other. Health improvement policies must consider subjective wellbeing. Well-being improvement policies need to be cognisant of the differences in provincial and population characteristics.