bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tunable quantum transport in topological semimetal candidates LaxSr1-xMnSb2
Authors: Song Jiangpeng , Li Junbo , Du Zan 
Published: August 2024

Abstract
The magnetic semimetal SrMnSb2 contains a nonsymmorphic crystal symmetry that could protect Dirac crossings, offering the coexistence of a quasi-two-dimensional characteristic, magnetic order and nontrivial topology in bulk single crystals. Here, we report the evolution of Fermi surfaces by probing quantum oscillations in the La
x
Sr1-x
MnSb2 single crystals. Hall measurements reveal that the conduction process changes from a hole-dominated multiband nature to a single hole-band nature after La doping. Compared with parent-SrMnSb2, the Fermi surface corresponding to F

α
is slightly enlarged and the small Fermi surface corresponding to F

γ
appears with a tunable feature in La-doped crystals. The topological semimetal candidates La
x
Sr1-x
MnSb2 provide a fine-tuning platform for potential applications in the future.
A comparison of dynamic warm-up and “warm-up” using self-massage tools on subsequent sit-and-reach displacement
Authors: Aquino Michele , DiMenna Frederick , Petrizzo John , Yusuff George , Otto Robert M. , Wygand John 
Published: August 2024

ObjectivesA dynamic warm-up (DWU) comprising exercise involving rhythmic muscle actions results in an acute increase in range of motion; however, recent findings suggest that a passive one using self-massage techniques might elicit a similar effect. This study’s purpose was to compare the acute effect of leg cycling DWU on sit-and-reach score to the effect of a preparatory regimen of foam rolling (FR) or percussive massage (PM).DesignSingle-blind, randomized, repeated-measures crossover study.MethodsThirty-two asymptomatic, physically-active participants (male;n= 17) aged 20.9 ± 1.5 years performed sit-and-reach tests before, immediately following and 10-, 20- and 30-minutes following eight minutes of each of the “warm-ups.” Analyses of variance at each time point across conditions and for the percent change elicited by each intervention were conducted to determine significant differences (p < 0.05).ResultsRepeated-measures ANOVA revealed a significant difference between mean percent difference of sit-and-reach score for FR (8.8 ± 0.5%) compared to DWU and PM (p = 0.046 and 0.048, respectively) while DWU (6.3 ± 0.8%) and PM (6.8 ± 0.5%) did not differ (p = 0.717). There were no differences between scores across interventions at any of the four time points.ConclusionsA bout of FR or PM resulted in an acute increase in a sit-and-reach score during a test performed immediately post and at 10-, 20- and 30-minutes post that was similar in magnitude to that which was present following leg cycling. These passive “warm-ups” are appropriate alternate strategies that can be employed to improve performance on a sit-and-reach test.
Stroke rehabilitation in urban and rural settings in the Philippines: Protocol for an interview and visual elicitation study
Authors: Buckingham Sarah Ann , Dar Juan Alyssa Marie , Demain Sara , De Vera June Ann , Estrada Myrna , Hermosura-Faeldon Lorraine , Kent Bridie , Linog Maria Teresa Sharon , Navea Roy Francis , Jones Fiona ,   on behalf of the TULAY project team
Published: August 2024

Introduction
There is a lack of community-based rehabilitation for stroke in the Philippines, and research on this topic is limited. Different challenges may be encountered in urban and rural settings. The aim of the Tulong, Ugnayan ng Lingap At gabaY (TULAY) project is to develop a context-appropriate, community-based stroke support programme, consisting of self-management and training resources to augment the rehabilitation and recovery process. An important stage in the development of this programme is to qualitatively explore the experiences and needs of all stakeholders.

Materials and methods
Using co-designed and evidence-based topic guides, in-depth semi-structured interviews will be conducted with people living with stroke, household carers and care providers. We will aim to gain a representation of different regions (within Luzon, Visayas, and Northern Mindanao), socioeconomic levels, and urban and rural locations. For people with stroke and household carers, interviews will be supplemented by auto-photography and visual elicitation to widen access for those that prefer to share their experiences visually or have communication problems. An interpretivist paradigm will be applied across all interview data and the consolidated criteria for reporting qualitative research (COREQ) will be followed. Thematic analysis will be undertaken using guidance by Braun and Clarke.

Discussion
To our knowledge, this study is the first of its kind in the Philippines. It has several methodological strengths, including the capture of perspectives from multiple stakeholders in diverse settings, the inclusion of people with communication difficulties, use of visual methods, and analysis in the native language. The findings will have various applications, including the potential to influence policy, practice and guidelines, and to inform the development of the TULAY stroke support programme.
How to get over with medication errors underestimation? Improving indices of medication errors with focus on intravenous medications in hematopoietic stem cell transplantation setting; a direct observation study
Authors: Mansouri Ava , Moazzeni Kiana , Valeh Maryam , Heidari Kazem , Hadjibabaie Molouk 
Published: August 2024

Background
The administration of intravenous (IV) medications is a technically complicated and error-prone process. Especially, in the hematopoietic stem cell transplantation (HSCT) setting where toxic drugs are frequently used and patients are in critical immunocompromised conditions, medication errors (ME) can have catastrophic reactions and devastating outcomes such as death. Studies on ME are challenging due to poor methodological approaches and complicated interpretations. Here, we tried to resolve this problem using reliable methods and by defining new denominators, as a crucial part of an epidemiological approach.

Methods
This was an observational, cross-sectional study. A total of 525 episodes of IV medication administration were reviewed by a pharmacist using the disguised direct observation method to evaluate the preparation and administration processes of 32 IV medications in three HSCT wards. We reported errors in 3 ratios; 1) Total Opportunities for Error (TOE; the number of errors/sum of all administered doses observed plus omitted medications), 2) Proportional Error Ratio (the number of errors for each drug or situation/total number of detected errors) and, 3) Corrected Total Opportunities for Errors (CTOE; the number of errors/ Sum of Potential Errors (SPE)).

Results
A total of 1,568 errors were observed out of 5,347 total potential errors. TOE was calculated as 2.98 or 298% and CTOE as 29.3%. Most of the errors occurred at the administration step. The most common potential errors were the use of an incorrect volume of the reconstitution solvent during medication preparation and lack of monitoring in the administration stage.

Conclusion
Medication errors frequently occur during the preparation and administration of IV medications in the HSCT setting. Using precise detection methods, denominators, and checklists, we identified the most error-prone steps during this process, for which there is an urgent need to implement effective preventive measures. Our findings can help plan targeted preventive measures and investigate their effectiveness, specifically in HSCT settings.
Latent toxoplasmosis, Cytomegalovirus, and Herpes Simplex Virus infections and risk of motorcycle accidents: A case-control study in a county with a high rate of motorcycle injuries in Iran
Authors: Rayatdoost Esmail , Chegin Mahdi , Taghipour Ali , Shadmand Enayat , Rezaei Fatemeh , Falahi Shahab , Kenarkoohi Azra , Badri Milad , Solhjoo Kavous , Abdoli Amir 
Published: August 2024

Background
Road traffic injuries (RTIs) are among the most important issues worldwide. Several studies reported that infection with the neurotropic parasite Toxoplasma gondii (T. gondii) increased the risk of car accidents. In this study, our objective was to investigate the possible associations among latent T. gondii, Cytomegalovirus (CMV), and Herpes Simplex Virus (HSV) infections with the risk of motorcycle accidents in Jahrom (Fars Province), which is a county with a high rate of motorcycle accidents in Iran.

Methods
In the setting of a case-control study; 176 motorcyclist men, including 88 survivors of motorcycle accidents and 88 motorcyclist without accidents, were considered as case and control groups, respectively. Rates of latent infections with T. gondii, CMV, and HSV were assessed by an enzyme-linked immunosorbent assay (ELISA).

Results
Eleven of 88 (12.5%) in the case group and 22 of 88 (25.0%) in controls were positive for anti-T. gondii IgG antibodies, this difference was statistically significant (OR = 0.42; CI: 0.19–0.95, p = 0.03). The general seroprevalence of CMV (94.3% in the case group vs. 87.5% in the control group, OR = 2.37; CI: 0.78–7.13, p = 0.12) and HSV (63.6% in the case group vs. 62.5% in the control group, OR = 1.05; CI: 0.57–1.94, p = 0.87) were not significantly different between the case and control groups.

Conclusions
Although latent toxoplasmosis has been associated with traffic accidents in recent reports, we found a negative association between latent toxoplasmosis and motorcycle accidents among survivors of these accidents. As such, latent CMV and HSV infections did not differ significantly between the cases compared to the control groups.
Optimal and Tolerant Conditions for Alginate and Calcium Chloride for the Semen Encapsulation of Pasundan Bull
Authors: Khan Ayesha , Manan Muhammad Abdul , Samsudewa Daud , Pamungkas Fitra Aji , Zulfiqar Hamza , Irfan Saad , Haidari Kiran , Wulandari Vidi , Hadi Didik Nurul 
Published: August 2024

The study aimed to determine the tolerance of Pasundan bull's sperm with different alginate and calcium chloride (CaCl2) concentrations to identify optimal conditions for sperm encapsulation. Semen samples were collected weekly with artificial vaginas from pasundan bulls. Pooled semen was divided into 9 equal volumes. The first sample was diluted with tris egg yolk extender (control), 4 samples were diluted with tris egg yolk extender supplemented with different concentrations of alginate (0.25, 0.5, 0.75, and 1%), and 4 other samples with CaCl2 (2.5, 5, 10, and 20 mM). Evaluation of semen was determined after 5 min incubation at room temperature and after overnight storage at 5 °C. Results showed that after 24h of refrigerated storage, the values for total motility and progressive motility in the groups with 2.5 mM CaCl2 and 0.25% alginate showed no difference compared to the control group. In contrast, a significant difference (P0.05) was found between the other groups with CaCl2 and alginate. The progressive motility value in the group with alginate concentration greater than 0.25% decreased significantly (P0.05). There was no difference between the groups (both alginate and CaCl2) in the spermatozoa viability and plasma membrane integrity variable. In conclusion, sperm with 2.5 mM calcium chloride and 0.25 % alginate was more tolerant of appropriate prolonged exposure and the sperm encapsulation process.
The Relationship Between Social Media Addiction and Self-Esteem in Medical Students of Diponegoro University
Authors: Subiyakto Difa Maulana , Saktini Fanti , Sumekar Tanjung Ayu 
Published: August 2024

Background: In the modern era, social media has become a necessity in carrying out daily activities. Playing social media too often can have negative effects. These negative effects include addiction. Social media addiction can interfere with daily activities and affect the level of self-esteem.Objective: To prove the relationship between social media addiction and selfesteem among medical students at Universitas Diponegoro.Methods: This research was an analytical observational investigation utilizing a cross-sectional methodology. The study was carried out over a span of one month, involving 90 participants from the medical students batch 2022 at Universitas Diponegoro. The questionnaires used were the Social Media Addiction Scale-Student Form (SMAS-SF) and Rosenberg Self Esteem Scale (RSES). The assessment of the correlation between social media addiction and self-esteem using the Spearman test.Results: 2.2% of respondents had a very low level of social media addiction; 52.2% had a low level; 44.4% had a high level; and 1.1% had a very high level. In terms of self-esteem, the data revealed that 84.4% of respondents had a high level of self-esteem, while 15.6% had a low level. In the correlation test between demographic factors, social media addiction, and self-esteem, an insignificant relationship was found with a p-value greater than 0.05. Meanwhile, a significant relationship was found in the correlation test between social media addiction and the level of self-esteem (p=0.001, r=-0.335).Conclusion: A significant relationship exists between social media addiction and the level of self-esteem among medical students at Diponegoro University.
Does Self-Esteem Affect Stress Levels in Final Year Medical Students? (A Study In Final Year Medical Students, Faculty Of Medicine, Diponegoro University)
Authors: Felita Fiona , Adiwijaya Janice Nathania , Hadiati Titis , Fitrikasari Alifiati , Savitri Soesmeyka 
Published: August 2024

Background: During young adulthood, individuals are forced to encounter countless and overwhelming challenges and responsibilities. Individuals are very prone during this period due to the fluctuation in self-esteem. Low self-esteem might significantly impact individuals as they could perceive challenges as distress, putting them at an increased risk of harming physical or mental health.Objective: To examine the relationship between self-esteem and stress levels among final year medical students, Faculty of Medicine, Diponegoro University. Methods: This research is an observational analytic correlational study with a cross-sectional design. Samples were obtained by total sampling method involving final year medical students, Faculty of Medicine, Diponegoro University (Class of 2018). Self-esteem was measured using the Rosenberg Self-esteem Scale (RSES), and stress levels were measured using the Perceived Stress Scale (PSS-10) that had been tested valid and reliable. Data were analyzed using Spearman and Lambda Correlation Tests.Results: There were 226 subjects involved in this research. Most subjects had high self-esteem (69,5%) and moderate level of stress (67,3%). Demographic factors (gender, residency status, academic achievement and economic status) were not significantly associated with self-esteem and stress levels. However, there was a significant relationship (p=0.000) between self-esteem and stress levels with moderate negative correlation (r=-0.385).Conclusion: There was a significant relationship between self-esteem and stress levels.
Szkoła życia. Wektory aksjologiczne w „Pamiętniku” Janusza Korczaka
Authors: Rudnicki Zbigniew 
Published: August 2024

Humanity found itself once again in a deep crisis. Its political and ecological dimensions are most frequently recognized, and recently its ecological ones. This provokes fundamental questions and a search for adequate answers, especially in the subtle realm of spiritual matters, where we also find values. It seems necessary to reconsider the effort to reflect on rudimentary issues and to turn to classical texts. The profound thoughts of Janusz Korczak in the Ghetto Diary, his last, very personal, and multi-threaded work as the “Old Doctor”, appear to be an excellent source here.
Novel variant in IGHM gene in a patient with agammaglobulinemia: A case report of a preschool child presenting with recurrent pneumonia
Authors: Heifetz Erin Joy , Sharifabadi Anahita Dehmoobad , Brager Rae , Garkaby Jenny 
Published: August 2024

Introduction: Agammaglobulinemia is a primary immunodeficiency characterized by absent B cells and originates from X-linked or autosomal mutations affecting B cell maturation. While the most common agammaglobulinemia is X-linked, one well-documented site of autosomal recessive agammaglobulinemia is within the immunoglobulin μ heavy chain protein, encoded by the IGHM gene. Such variants frequently result in clinical presentations of recurrent bacterial infections early in life. Aim: To describe a case of a five-year-old female with agammaglobulinemia resulting from a novel homozygous IGHM variant, presenting with pneumonia complicated by empyema and H. influenzae bacteremia. Methods: Case data was compiled retrospectively from the patient’s medical chart, including relevant laboratory testing for immunoglobulins, quantitative B cell subsets, and genetic testing using a primary immunodeficiency panel. Results: The proband is a 5-year-old female with a history of recurrent pneumonia, presenting with H. influenzae bacteremia in the context of pneumonia complicated by an empyema. Investigations revealed low immunoglobulin levels, absent vaccine responses, and undetectable B cells on flow cytometry. Genetic testing revealed a novel homozygous variant in the IGHM gene: c.775T>C, p.Trp259Arg. Conclusion: Autosomal recessive agammaglobulinemia is a rare but severe, treatable disorder of the immune system which typically presents in early childhood. Hypomorphic mutations, while less commonly reported in the literature, are an important consideration in atypical presentations of primary immunodeficiencies, such as in the case presented. Statement of Novelty: Herein, we report a case of agammaglobulinemia presenting with a novel homozygous variant in the IGHM gene leading to later onset agammaglobulinemia in a 5-year-old female.
Alterations in cardiac contractile and regulatory proteins contribute to age‐related cardiac dysfunction in male rats
Authors: Han Young Soo , Pakkam Madona , Fogarty Matthew J. , Sieck Gary C. , Brozovich Frank V. 
Published: August 2024

AbstractAging is associated with cardiac contractile abnormalities, but the etiology of these contractile deficits is unclear. We hypothesized that cardiac contractile and regulatory protein expression is altered during aging. To investigate this possibility, left ventricular (LV) lysates were prepared from young (6 months) and old (24 months) Fischer344 rats. There are no age‐related changes in SERCA2 expression or phospholamban phosphorylation. Additionally, neither titin isoform expression nor phosphorylation differed. However, there is a significant increase in β‐isoform of the myosin heavy chain (MyHC) expression and phosphorylation of TnI and MyBP‐C during aging. In permeabilized strips of papillary muscle, force and Ca2+ sensitivity are reduced during aging, consistent with the increase in β‐MyHC expression and TnI phosphorylation. However, the increase in MyBP‐C phosphorylation during aging may represent a mechanism to compensate for age‐related contractile deficits. In isolated cardiomyocytes loaded with Fura‐2, the peak of the Ca2+ transient is reduced, but the kinetics of the Ca2+ transient are not altered. Furthermore, the extent of shortening and the rates of both sarcomere shortening and re‐lengthening are reduced. These results demonstrate that aging is associated with changes in contractile and regulatory protein expression and phosphorylation, which affect the mechanical properties of cardiac muscle.
Socioeconomic status as a risk factor for SARS-CoV-2 infection in pregnant women
Authors: Lastinger Julia , Gerich Joachim , Beham-Rabanser Martina , Stelzl Patrick , Trautner Philip Sebastian , Enzelsberger Simon-Hermann , Altmann Reinhard , Shebl Omar , Oppelt Peter , Enengl Sabine 
Published: August 2024

Abstract

Objectives
Due to the association between COVID-19 and adverse pregnancy outcomes, pregnant women are considered to be a vulnerable patient group. Studies have shown that low socioeconomic status (SES) is a risk factor for SARS-CoV-2 infection. COVID-19 and low SES are likely to have a synergistic adverse effect. This study aimed to evaluate the socioeconomic background, indicated by self-reported SES, educational level, and financial situation, in pregnant women who were positive for SARS-CoV-2.

Methods
A case-control study was conducted, including all pregnant women with positive SARS-CoV-2 PCR tests at Kepler University Hospital Linz between May 2020 and August 2021 (n=150) and a control group matched 1:1 relative to gestational age at birth (n=150). Data were collected using written questionnaires and medical records from the hospital information system.

Results
Lower self-reported socioeconomic status (p=0.029) and lower education level (p=0.003) were detected in the COVID group. Mothers in the COVID group were significantly younger (p=0.024). However, after adjustment for educational attainment, younger age was not confirmed as a risk factor for SARS-CoV-2 infection during pregnancy (p=0.326). The social gradient was not explained by the assumed mediators and confounders.

Conclusions
These findings confirm an association between lower socioeconomic status and the risk of SARS-CoV-2 infection during pregnancy. Since both socioeconomic factors and COVID-19 impose negative effects on pregnancy outcomes, health inequalities should be taken into consideration when implementing SARS-CoV-2 prevention measures and when providing health care for pregnant women from disadvantaged communities.
Conservative Profitability Evaluation for a Newsboy-Type Product: Frequentist Approach versus Bayesian Approach
Authors: Su Rung-Hung , Hou Chia-Ding , Wu Chia-Huang , Lin Cheng-I 
Published: August 2024

Abstract
Retailers in competitive markets must determine the optimal order quantity of the product while ensuring that the product keeps a stable performance of profitability. The achievable capacity index (ACI) has a streamlined form to measure the profitability of a newsboy-type product with normally distributed demand. In situations wherein the parameters of the normal distribution are unknown, it is also possible to estimate accurate ACI values using statistical approaches based on historical demand; however, the results tend to vary with the statistical approaches employed (e.g., frequentist or Bayesian). Furthermore, point estimates of ACI lead to overestimates of profitability due to sampling error. This study used frequentist and Bayesian approaches to derive the lower confidence bounds of ACI with the aim of obtaining conservative estimates of profitability. The comparison of the levels of conservatism and confidence between the two approaches was also explored. Our results could be used as a guide for the selection of approaches by which to estimate profitability.