bluuebunny/crossref_metadata_2025_split huggingface dataset:
Red ear syndrome: a case series and review of the literature
Authors: Callan Grace M. , Freitag Frederick , Tolebeyan Amir Soheil 
Published: July 2024

Abstract
Background
Red Ear Syndrome is a burning sensation and erythema of the ear, associated with a various number of disorders including migraine, trigeminal neuralgia, autoimmune disorders etc. Theories for RES pathophysiology have developed from current understandings of comorbid conditions. Characterizing the underlying mechanism of RES is crucial for defining effective treatments.

Case presentation
Three caucasian patients, ages 15, 47, and 67 years, with migraine, one with erythromelalgia are reported in this manuscript. RES pathophysiology is not fully understood due to its variable clinical presentation and numerous comorbid conditions, making it difficult to identify effective treatments.

Conclusion
RES seems to be largely treatment-resistant, and most options involve treating the associated disorders and minimizing pain. Further investigation of future cases should lead to a more comprehensive understanding of the fundamental cause of RES and, hopefully, successful treatments.
Cross-species transmission and histopathological variation in specific-pathogen-free minipigs infected with different hepatitis E virus strains
Authors: Jung Soontag , Yeo Daseul , Seo Dong-Joo , Choi In-Soo , Choi Changsun 
Published: July 2024

AbstractHepatitis E virus (HEV) is a major cause of viral hepatitis worldwide. Pigs are the natural host of HEV genotype 3 and the main reservoir of HEV. As the host range of HEV genotype 3 expands, the possibility that HEV from various species can be transmitted to humans via pigs is increasing. We investigated the potential cross-species transmission of HEV by infecting minipigs with swine HEV (swHEV), rabbit HEV (rbHEV), and human HEV (huHEV) and examining their histopathological characteristics and distribution in various organs. Fifteen specific-pathogen-free Yucatan minipigs were infected with swHEV, rbHEV, huHEV, or a mock control. In the present study, we analysed faecal shedding, viremia, and serological parameters over a seven-week period. Our results indicated that swHEV exhibited more robust shedding and viremia than non-swHEVs. Only swHEV affected the serological parameters, suggesting strain-specific differences. Histopathological examination revealed distinct patterns in the liver, pancreas, intestine, and lymphoid tissues after infection with each HEV strain. Notably, all three HEVs induced histopathological changes in the pancreas, supporting the association of HEVs with acute pancreatitis. Our results also identified skeletal muscle as a site of HEV antigen presence, suggesting a potential link to myositis. In conclusion, this study provides valuable insights into the infection dynamics of different HEV strains in minipigs, emphasizing the strain-specific variations in virological, serological, and histological parameters. The observed differences in infection kinetics and tissue tropism will contribute to our understanding of HEV pathogenesis and the potential for cross-species transmission.
Predictive value of dynamic arterial elastance for vasopressor withdrawal: a systematic review and meta-analysis
Authors: Alvarado-Sánchez Jorge Iván , Salazar-Ruiz Sergio , Caicedo-Ruiz Juan Daniel , Diaztagle-Fernández Juan José , Cárdenas-Bolivar Yenny Rocio , Carreño-Hernandez Fredy Leonardo , Mora-Salamanca Andrés Felipe , Montañez-Nariño Andrea Valentina , Stozitzky-Ríos María Valentina , Santacruz-Herrera Carlos , Ospina-Tascón Gustavo Adolfo , Pinsky Michael R. 
Published: July 2024

Abstract
Background
Dynamic arterial elastance (Eadyn) has been investigated for its ability to predict hypotension during the weaning of vasopressors. Our study focused on assessing Eadyn’s performance in the context of critically ill adult patients admitted to the intensive care unit, regardless of diagnosis.

Main body
Our study was conducted in accordance with the Preferred Reported Items for Systematic Reviews and Meta-Analysis checklist. The protocol was registered in PROSPERO (CRD42023421462) on May 26, 2023. We included prospective observational studies from the MEDLINE and Embase databases through May 2023. Five studies involving 183 patients were included in the quantitative analysis. We extracted data related to patient clinical characteristics, and information about Eadyn measurement methods, results, and norepinephrine dose. Most patients (76%) were diagnosed with septic shock, while the remaining patients required norepinephrine for other reasons. The average pressure responsiveness rate was 36.20%. The synthesized results yielded an area under the curve of 0.85, with a sensitivity of 0.87 (95% CI 0.74–0.93), specificity of 0.76 (95% CI 0.68–0.83), and diagnostic odds ratio of 19.07 (95% CI 8.47–42.92). Subgroup analyses indicated no variations in the Eadyn based on norepinephrine dosage, the Eadyn measurement device, or the Eadyn diagnostic cutoff to predict cessation of vasopressor support.

Conclusions
Eadyn, evaluated through subgroup analyses, demonstrated good predictive ability for the discontinuation of vasopressor support in critically ill patients.
Research hotspots and trends of spinal cord stimulation for neuropathic pain: a bibliometric analysis from 2004 to 2023
Authors: Zhang Liwen , Li Zhenhua , Gu Haiyan , Chen Jinyan , Zhang Yanping , Yu Yuanyuan , Wang Hexiang 
Published: July 2024

AbstractThe purpose of this study is to systematically analyze the development trend, research hotspots, and future development direction on the treatment of neuropathic pain (NP) with spinal cord stimulation through bibliometric method. We extracted the literature related to the treatment of NP with spinal cord stimulation from January 2004 to December 2023 from the Web of Science database. As a result, a total of 264 articles were retrieved. By analyzing the annual published articles, authors, countries, institutions, journals, co-cited literature, and keywords, we found that the count of publication in this field has been experiencing an overall growth, and the publications within the past 5 years accounted for 42% of the total output. Experts from the United States and the UK have made significant contributions in this field and established a stable collaborative team, initially establishing an international cooperation network. Pain is the frequently cited journal in this field. The study on spinal cord stimulation therapy for NP especially the study on spinal cord stimulation therapy for back surgery failure syndrome (FBSS) and its potential mechanisms are the research hotspots in this field, while the study on novel paradigms such as high-frequency spinal cord stimulation and spinal cord burst stimulation represents the future development directions. In short, spinal cord stimulation has been an effective treatment method for NP. The novel paradigms of spinal cord stimulation are the key point of future research in this field.
“Exploring the relationship of organizational virtuousness, citizenship behavior, job performance, and combatting ostracism” through structural equational modeling
Authors: Gogia Eimad Hafeez , Shao Zhen , Khan Karamat , Rehman Mohd Ziaur , Haddad Hossam , Al-Ramahi Nidal Mahmoud 
Published: July 2024

Abstract
Background
This theoretical model has been drawn on principles of social exchange theory to scrutinize the connection between organizational virtuousness and job performance with the mediating role of Organizational citizenship behavior and moderating role of workplace ostracism. A survey was conducted in Pakistan, gathering data from 486 employees working for various private and commercial banks.

Method
Soft and hard questionnaires were distributed to the participants, with social media platforms used for the soft questionnaires and meetings with employees for the hard questionnaires. A 7-point Likert scale was employed in data collection, and measures for the variables were adapted from reliable and valid sources. A demographic analysis was performed to summarize the sample collected from participants. The demographics results were analyzed using SPSS, while the measurement model and path analysis were conducted using Structural Equational Modeling with Smart PLS-4.

Results
The study’s findings showed a significant and positive relationship between organizational virtuousness and job performance, with organizational citizenship behavior serving as a mediator. Additionally, a negative moderation of workplace ostracism was observed in the mediation of organizational citizenship behavior toward the relationship between organizational virtuousness and job performance.

Conclusion
The study’s results contribute to the implementation of social exchange theory and related concepts in the banking sector of Pakistan, providing practical guidance for implementing virtuous practices within organizations and discouraging ostracism in banks to enhance overall performance. The study suggests that policies regarding the implementation of virtuous practices in organizations can be established, and workplace ostracism can be avoided by providing a platform for social gatherings and training employees. Managers should adopt appropriate leadership styles and relevant communication patterns to impact the organizational climate which can also help reduce the influence of ostracism in the organization. Additionally, a complaint cell should be established with complete confidentiality to reduce ostracism.
Timing limits of ultrafast cross-luminescence emission in CsZnCl-based crystals for TOF-CT and TOF-PET
Authors: Herweg Katrin , Rutstrom Daniel , Nadig Vanessa , Stand Luis , Melcher Charles L. , Zhuravleva Mariya , Schulz Volkmar , Gundacker Stefan 
Published: July 2024

Abstract
Background
Good timing resolution in medical imaging applications such as TOF-CT or TOF-PET can boost image quality or patient comfort significantly by reducing the influence of background noise. However, the timing resolution of state-of-the-art detectors in CT and PET are limited by their light emission process. Core-valence cross-luminescence is an alternative, but well-known compounds (e.g. BaF2) pose several problems for medical imaging applications, such as their emission wavelength in the deep UV. CsZnCl-based materials show promise to solve this issue, as they provide fast decay times of 1–2 ns and an emission wavelength around 300 nm.

Results
In this work, we investigated two CsZnCl-compounds: Cs2ZnCl4 and Cs3ZnCl5. We validated the previously published decay times on a time-correlated single-photon counting setup with 1.786 ± 0.016 ns for Cs2ZnCl4 and 1.034 ± 0.013 ns for Cs3ZnCl5. The setup’s high resolution enabled the discovery of an additional prompt emission component with a significant abundance of 98 ± 18 (Cs2ZnCl4) and 86 ± 14 (Cs3ZnCl5) photons/MeV energy deposit. In a PET coincidence experiment, we measured the best coincidence time resolution (CTR) of 62 ps (FWHM) for Cs2ZnCL4 coupled to FBK VUV SiPMs with silicon oil. To assess the CTR for lower energies, we filtered the energy along the Compton continuum and found a deteriorated CTR that seems to be mainly influenced by photon statistics. Furthermore, this study gave us a rough estimate of e.g. 150 ps (FWHM) CTR at 100 keV energy for Cs2ZnCL4. From measurements with high activity of 14 MBq to check for pile-up effects we assume that Cs2ZnCl4 is better suited for high-rate time-of-flight applications than lutetium-based oxides. Simulations demonstrated that the stopping power of Cs2ZnCl4 is lower than for LSO:Ce,Ca, meaning that a high amount of material would be needed for TOF-PET applications. However, the stopping power seems acceptable for applications in TOF-CT.

Conclusions
The fast decay time, state-of-the-art CTR in benchtop experiments and high-rate suitability make CsZnCl materials a promising candidate for time-of-flight experiments. We consider especially TOF-CT a suitable application due to its relatively low X-ray energies (~ 100 keV) and the thusly acceptable stopping power of Cs2ZnCl4. Currently, further exploration of the prompt emission and its creation mechanism is planned, as well as investigating the light transport of Cs2ZnCl4 in longer crystals.
Recommendations on cutaneous and hematological manifestations of Sjögren’s disease by the Brazilian Society of Rheumatology
Authors: Pugliesi Alisson , Egypto Danielle Christinne Soares do , Duffles Guilherme , Cantali Diego Ustárroz , Pasoto Sandra Gofinet , Oliveira Fabiola Reis , Valim Valeria , Lopes Maria Lucia Lemos , Miyamoto Samira Tatiyama , Fernandes Marilena Leal Mesquita Silvestre , Fialho Sonia Cristina de Magalhães Souza , Pinheiro Aysa César , Santos Laura Caldas dos , Appenzeller Simone , Ribeiro Sandra Lucia Euzébio , Libório-Kimura Tatiana Nayara , Santos Maria Carmen Lopes Ferreira Silva , Gennari Juliana D´Agostino , Pernanbuco Roberta , Capobiano Karina Gatz , Civile Vinicius Tassoni , Pinto Ana Carolina Pereira Nunes , Rocha-Filho César Ramos , Rocha Aline Pereira da , Trevisani Virginia Fernandes Moça 
Published: July 2024

AbstractSjogren’s disease (SjD) is an autoimmune disease that is characterized not only by the sicca symptoms it causes but also by its systemic nature, which is capable of several and not yet fully understood extraglandular manifestations. To gain a clearer understanding of these manifestations as well as a better practical approach, a panel of experts from the Brazilian Society of Rheumatology conducted a systematic review and meta-analysis on the identification of epidemiologic and clinical features of the extraglandular manifestations present in ESSDAI (EULAR Sjogren´s syndrome disease activity index), followed by a voting panel with recommendations for clinical practice. This publication is complementary to others already published and covers cutaneous and hematological manifestations, with prevalence data generated by a meta-analysis of 13 clinical or laboratory manifestations and 6 clinical management recommendations.
A rare case of hepatic hydatid cyst in Somalia: a case report
Authors: Mohamud Mohamed Adam , Omar Abdirahman Ahmed , Adam Mohamed Hussein , Elaagip Arwa , İbrahim Ismail Gedi 
Published: July 2024

Abstract
Background
Echinococcosis, or hydatid disease, is caused by the larval forms of taeniid cestodes belonging to the genus Echinococcus. Echinococcus granulosus and E. multilocularis are the primary species responsible for human echinococcosis, and mostly they affect the liver. The disease course is typically slow, and the patients tend to remain asymptomatic for many years.

Case presentation
A case of 19-year-old male Somali from Medina, Saudi Arabia, was presented to the Mogadishu Somali Turkey Recep Tayyip Erdogan Training and Research Hospital with the complaint of right upper quadrant abdominal pain and dysuria for 1 month. A thorough physical examination, laboratory examination, and imaging investigations, including abdominal sonography and computed tomography (CT), were conducted.
Both ultrasound and CT scans revealed a cystic lesion in the right lobe of the liver, confirming the diagnosis of a hydatid cyst. Consequently, the patient underwent exploratory laparotomy. It was successfully managed surgically, and the definitive diagnosis was provided by the pathologist, confirming degenerated echinococcal cysts that contain abundant debris. Additionally, the patient received oral albendazole both before and after the surgery and after 7 months and is currently symptom-free.

Conclusions
Hydatid disease in the liver may persist without symptoms and often goes undiagnosed due to the slow growth of the cysts. The diagnosis needs careful history reporting, physical examination, and appropriate imaging investigations.
Hepatic cholera: a case report with literature review
Authors: Khatana Gaurav , Unnikrishnan Lal Krishna , Kolassery Sandesh , Sebastian Saji , Nair Sindhu Radha Sadasivan , Muraleedharanpillai Ramu 
Published: July 2024

Abstract
Background
Vasoactive intestinal peptide-secreting tumors (VIPomas), also known as WDHA syndrome (or “pancreatic cholera”), are rare neuroendocrine tumors (NETs) with an incidence of 0.05 to 2%. It secretes excessive amounts of VIP, leading to watery diarrhea, hypokalemia, and hypochlorhydria. In adults, they occur most commonly between the ages of 30 and 50 years and are mostly intrapancreatic, occurring in the tail of the pancreas, and rarely located in other segments of the gastrointestinal tract, such as the adrenal glands (35%), paraspinal retroperitoneal ganglia (30–35%), posterior mediastinum (20%), head and neck (1–5%), pelvis (2–3%), and rarely (1%) thymus, lung, kidney, anterior mediastinum, and liver.

Case presentation
Our patient, a 22-year-old man, was admitted with recurrent episodes of large-volume chronic watery diarrhea, generalized muscle weakness, and significant weight loss. After a complete workup, a solitary primary hepatic VIPoma was diagnosed. The patient underwent surgical resection of the liver lesion. Following surgery, there was immediate regression of diarrhea and electrolyte abnormalities, with no recurrence at the 1-year follow-up.

Conclusion
Neuroendocrine tumors, particularly VIPomas, are rare and mostly intrapancreatic. Solitary primary hepatic VIPoma is extremely rare, and to the best of our knowledge, only four cases without any evidence of a pancreatic lesion have been reported. Diagnosis remains challenging, as it is often not detected on conventional imaging. The prognosis mostly depends on tumor grade, stage, and surgical resectability.
Social media influencer streamers and live-streaming shopping: examining consumer behavioral intention through the lens of the theory of planned behavior
Authors: Long Junyu , Zaidin Norzaidahwati , Mai Xiaojun 
Published: July 2024

AbstractThe rapid development of live streaming has given rise to live-streaming shopping, a novel channel of online shopping that has gained considerable market value. While previous studies have explored various factors influencing consumers' intentions to engage in live-streaming shopping, most have focused on factors influencing behavioral intention after consumers have already chosen live-streaming as their online shopping channel. Few studies have focused on the beginning of the entire shopping journey—the intention of consumers to choose live-streaming shopping. To fill this research gap, this study extends the theory of planned behavior by introducing social media influencer streamers as an exogenous variable. We investigated how attitudes toward live-streaming shopping, subjective norms, perceived behavioral control, and social media influencer streamers collectively influence the consumer’s intention for live-streaming shopping. To achieve those research objectives, the study distributed an online questionnaire across four specific regions in the Chinese market. By using stratified sampling and purposive sampling methods, we garnered 385 valid responses from those four regions. The study employed partial least squares structural equation modelling and SmartPLS 4.0 for data analysis. Consequently, the results show that both attitudes toward live-streaming shopping, subjective norms, perceived behavioral control, and social media influencer streamers have a significant on consumers’ intention for live-streaming shopping. Moreover, social media influencer streamers exhibit significant influences on consumers’ attitudes toward live-streaming shopping, subjective norms, and perceived behavioral control.
An effective investigation of chatter prediction system on Al6061 alloy in an end milling process
Authors: C Trivikrama Raju , S Jakeer Hussain , G Yedukondalu , Kolli Murahari 
Published: July 2024

AbstractVisual examination of the surface topography, in conjunction with the other sensors, may confirm the existence of chatter. Online chatter detection during real machining operations is possible with the use of sensors, and the presence of noise in their output and restricted bandwidth are the major drawbacks of these sensors. Productivity drops and manufacturing costs go up when there is a lot of chatter in the machining process. In the present paper, an integrated spindle tool system is modeled using finite element method with Timoshenko beam theory including rotational and shear deformation effects. To maximize the average stable depth of cut in an end milling process while simultaneously minimizing the chatter vibration levels, real time and offline strategies have been investigated. Machining experiments performed on Al6061-alloy specimens provide an empirical confirmation of the stability boundaries. The surface topography methods such as scanning electron microscope (SEM) and optical microscope images along with vibration levels are considered, to identify chatter marks under various machining conditions, which helps to assure cutting process stability. Stability lobe diagrams are plotted with these derived conditions and observed at an incremental level in the axial depths of the cut. The methodology shown in this paper improves the machining stability of the end milling with the reduction in the tool tip vibrations.
Preparation of a monoclonal antibody against recombinant LSDV034 protein and its application in detecting lumpy skin disease virus through a competitive enzyme-linked immunosorbent assay (cELISA)
Authors: Yuan Xinwei , Zhao Hui , Ji Wanfeng , Yan Xiaohan , Xiang Zhijie , Yang Li , Geng Yuanchen , Chen Yingyu , Chen Jianguo , Chen Xi , Zhang Lei , Hu Changmin , Guo Aizhen 
Published: July 2024

AbstractLumpy skin disease (LSD) is a highly contagious disease caused by lumpy skin disease virus (LSDV) in bovines. Rapid and accurate diagnosis is very important to controll it. However, current commercial detection kits need to be improved in terms of sensitivity or specificity. This study aimed to develop a novel diagnostic competitive enzyme-linked immunosorbent assay (cELISA) based on the newly identified antigen gene LSDV034. The rLSDV034 protein was identified as a potential diagnostic antigen, and it was expressed, purified, and used to immunize BALB/c mice. Using laboratory-prepared indirect ELISA (iELISA), the positive cell lines were screened, and their blocking activity was further verified by competitive ELISA (cELISA). The cell line, 1H7, was chosen to produce mouse ascites, which were purified for a monoclonal antibody (mAb, 5.395 mg/mL). The heavy chain type of the 1H7 mAb was identified as IgG1a, and its light chain subtype was identified as κ. Furthermore, cELISA was developed to detect bovine serum antibodies, with rLSDV034 (4 μg/mL) as the coating antigen and HRP-1H7 mAb (1:300) as the competitive antibody. The cutoff value of cELISA was 55%, based on 32 negative bovine serum samples. The analytical sensitivity was 1:8, and no cross-reaction was detected with bovine viral diarrhea virus (BVDV), infectious bovine rhinotracheitis virus (IBRV), Pasteurella multocida (P. multocida), or Mycoplasma bovis (M. bovis) from the serum samples. The diagnostic sensitivity and specificity of cELISA were 98.46% (95% confidence interval, CI: 91.7–100) and 100% (95% CI: 89.1–100), respectively, based on the analysis of 30 LSDV-infected bovine serum samples, 35 GTPV-vaccinated samples, and 32 negative samples. The overall coincidence of the cELISA with the virus neutralization test (VNT) reached 98.97% (95% CI: 94.4–100). Furthermore, we used cELISA to analyze 230 clinical bovine serum samples (including 59 infected and 171 vaccinated samples) and found that the serum positivity rates of the immunized samples (on d 60 postimmunization) and infected samples were 77.78% (95% CI: 70.8–83.8%) and 71.19% (95% CI: 57.9–82.2), respectively. These results indicate that the developed cELISA is promising for detecting serum antibodies in naturally infected or vaccinated cattle.