bluuebunny/crossref_metadata_2025_split huggingface dataset:
Examining the Relationship between Cultural Globalization and Marriage Spaces: The Mediating Role of Modern Identity
Authors: Mirzaei Ezatalah , Moghadam Elham Keshavarz , Asgari Ehsan , Mirzaei Mahdi 
Published: July 2024

Aim: The purpose of writing this article was to investigate the relationship between cultural globalization and marriage spaces, relying on the mediating role of modern identity. Methods: The research type was descriptive and survey methodology was used. The total sample size consisted of 271 students of Al-Zahra University (S) who were married between the years 2020 and 2023, and this number was able to fill out the Mirzaei’s (2021) Cultural Globalization and the Kianpour et al. (2015) and Afsharian (2021) Modern Identity Questionnaire. The collected data were analyzed and interpreted using SPSS and AMOS softwares. Results: In terms of effecting the dimensions of the dependent variable (spouse selection spaces), the highest rate was related to the relationship between individualism and the unsupervised spousal selection space (0.77); this means that the higher the level of individualism, the higher the number of unsupervised marriages and vice versa. The lowest level of correlation was also seen between the variables of using Iranian music and the atmosphere of passive supervision in choosing a spouse (0.16). Also, relying on the Sobel test, it was determined that the value of this statistic in all variables is greater than ±1.96, and this means that the modern identity variable has played a significant mediating role in the relationship between cultural globalization and spouse selection spaces. Conclusion: Considering the limitless expansion of communication and the internet and virtual space that is accessible to everyone, the religious-traditional fabric of Iranian society, as well as the decrease in the marriage rate and the increase in the divorce rate in the current era, it seems that the authorities should adopt appropriate policies and providing basic and important schemas by experts and university professors is more and more able to return the atmosphere of marriage and choosing a spouse to the past and its traditional state and also to overcome such alarming statistics related to the categories of marriage and divorce. In other words, it is necessary to think of measures to pay attention to the rich traditional culture so that the identity of Iranians does not suffer from contradictions and conflicts.
Addressing Violence Against Women and Children Through the 'Lapor Pak 129' Innovation
Authors: Pusparini Rani 
Published: July 2024

Abstract
This study aims to elucidate the service innovations implemented by the Office of Women's Empowerment and Child Protection and Population of the East Java Provincial Government to provide protection against violence towards women through the LAPOR PAK 129 innovation. The number of complaints of violence against women and children is quite high. Therefore, the Office of Women's Empowerment and Child Protection and Population of East Java Province developed this innovation to address the issue. It serves not only as a platform for receiving complaints of violence against children and women but also provides health services, social rehabilitation services, legal aid and enforcement services, as well as repatriation and social reintegration services. This study employs a qualitative method. Data collection techniques include interviews, observations, and document studies. This study applies interactive data analysis. The results of the "LAPOR PAK 129" innovation by DP3AK East Java aim to provide protection and services to women and children from violence through a toll-free telephone service and updated complaint procedures. This innovation encompasses non-discriminatory policies, active participation of children in recovery, and a new governance system, thereby enhancing the ease, convenience, and effectiveness of services.
Keywords: innovation, service, violence, women and children.

Abstrak
Penelitian ini bertujuan menjelaskan inovasi pelayanan yang dijalankan oleh Dinas Pemberdayaan Perempuan dan Perlindungan Anak dan Kependudukan (DP3AK) Pemerintah Provinsi Jawa Timur dalam memberikan perlindungan terhadap kekerasan perempuaan melalui inovasi LAPOR PAK 129. Pengaduan kekerasan Perempuan dan anak cukup tinggi. Oleh karena itu, Dinas Pemberdayaan Perempuan dan Perlindungan Anak dan Kependudukan Provinsi Jawa Timur membuat inovasi untuk menangani permasalahan tersebut. Tidak hanya sebagai tempat dalam menerima pengaduan kekerasan terhadap anak dan Perempuan saja, tetapi memberikan layanan kesehatan, layanan rehabilitasi sosial, layanan bantuan dan penegak hukum, hingga layanan pemulangan dan reintegrasi sosial. Penelitian ini menggunakan metode kualitatif. Teknik pengumpulan data dilakukan dengan cara wawancara, observasi dan studi dokumentasi. Penelitian ini menerapkan analisis data interaktif. Hasil penelitian Inovasi "LAPOR PAK 129" oleh DP3AK Jawa Timur bertujuan untuk memberikan perlindungan dan pelayanan kepada perempuan dan anak dari kekerasan melalui layanan telepon bebas pulsa dan pembaruan prosedur pengaduan. Inovasi ini mencakup kebijakan nondiskriminasi, partisipasi aktif anak dalam pemulihan, serta sistem tata kelola baru, sehingga meningkatkan kemudahan, kenyamanan, dan efektivitas pelayanan.
Kata kunci: inovasi, pelayanan, kekerasan, perempuan dan anak.
Propuesta para incrementar el uso de energía solar fotovoltaica en Ámsterdam. = Strategic guidelines to increase the use of photovoltaic solar energy in Amsterdam
Authors: Piña Henríquez Elvimar , Millán Aguilar Celina 
Published: July 2024

ResumenLa energía solar fotovoltaica (ESF) es una de las estrategias de Países Bajos para cumplir la meta de reducción de Gases Efecto Invernadero (GEI). Ámsterdam presenta debilidad en el uso de esta energía, por lo que se procuró identificar las barreras que impiden su uso, con el objetivo de formular lineamientos estratégicos para el incremento en el uso de la ESF enmarcado en la sostenibilidad urbana. Para ello se desarrolló esta investigación con un enfoque mixto, a través de revisión documental y de campo con instrumentos aplicados a los actores involucrados. Los resultados indicaron que las barreras que impiden incrementar el uso de la energía solar están relacionadas con la falta de información, conocimiento, integración social y recursos financieros. La información obtenida da lugar a la generación de lineamientos estratégicos para aumentar el uso de la ESF y contribuir al logro de las metas climáticas locales, nacionales e internacionales. AbstractPhotovoltaic solar energy (ESF) is one of the strategies of the Netherlands to meet the goal of reducing Greenhouse Gases (GHG). Amsterdam presents a weakness in the use of this energy, so an attempt was made to identify the barriers that prevent its use, with the objective of formulating strategic guidelines for the increase in the use of the ESF framed in urban sustainability. For this, this research was developed with a mixed approach, through documentary and field review with instruments applied to the actors involved. The results indicated that the barriers that prevent increasing the use of solar energy are related to the lack of information, knowledge, social integration and financial resources. The information obtained leads to the generation of strategic guidelines to increase the use of the ESF and contribute to the achievement of local, national and international climate goals.
A Surgical Skills Rotation for Mid-Level Residents
Authors: Nguyen Lanchi B. , Long Steven A. , Lawler Ericka A. , Karam Matthew D. 
Published: July 2024

Introduction:
The University of Iowa orthopaedic residency previously designed a month-long surgical skill rotation for postgraduate year (PGY)-1 residents. This successful initiative has become a model of interest for other teaching institutions. In addition to the intern year, an important phase in residency occurs during the transition from PGY2 to PGY3, when residents assume greater responsibility and autonomy in leading surgical procedures.

Methods:
To directly address this transition and assess residents' readiness, our residency program established a week-long PGY2 surgical skills rotation. This rotation serves as a training checkpoint and focuses on both training and evaluation of level-appropriate skills in joint arthroplasty, trauma, arthroscopy, and wire navigation. The primary objective of the PGY2 surgical skills rotation is to enhance orthopaedic residents' operative skills and experience by providing increased exposure and practice of requisite technical skills. Similar to the Orthopedic In-Training Examinations that assess residents' knowledge, this week-long program, aimed at assessing residents' proficiency in fundamental orthopaedic technical skills, occurs before their PGY3 year.

Results:
Faculty-led training and assessment sessions in each area offer residents many opportunities for dedicated practice and improvement. Transferring these acquired skills from the laboratory to the operating room is essential for a training program. To confirm improvement, the final day of the surgical skills rotation was exclusively dedicated to structured performance evaluations, with a specific emphasis on establishing proficiency benchmarks.

Conclusion:
We herein describe the University of Iowa's PGY2 surgical skills rotation, providing insights into its development, implementation, and outcomes. By sharing our experience, we offer a framework for other academic departments seeking to optimize surgical skills education and ensure the successful transition of mid-level residents.
Polygenic scores for psychiatric traits mediate the impact of multigenerational history for depression on offspring psychopathology
Authors: Cha Jiook , Lee Eunji , Dijk Milenna van , Kim Bogyeom , Kim Gakyung , Murphy Eleanor , Talati Ardesheer , Joo Yoonjung , Weissman Myrna 
Published: July 2024

Abstract

A family history of depression is a well-documented risk factor for offspring psychopathology. However, the genetic mechanisms underlying the intergenerational transmission of depression remain unclear. We used genetic, family history, and diagnostic data from 11,875 9–10 year-old children from the Adolescent Brain Cognitive Development study. We estimated and investigated the children’s polygenic scores (PGSs) for 30 distinct traits and their association with a family history of depression (including grandparents and parents) and the children's overall psychopathology through logistic regression analyses. We assessed the role of polygenic risk for psychiatric disorders in mediating the transmission of depression from one generation to the next. Among 11,875 multi-ancestry children, 8,111 participants had matching phenotypic and genotypic data (3,832 female [47.2%]; mean (SD) age, 9.5 (0.5) years), including 6,151 [71.4%] of European ancestry). Greater PGSs for depression (estimate = 0.129, 95% CI = 0.070–0.187) and bipolar disorder (estimate = 0.109, 95% CI = 0.051–0.168) were significantly associated with higher family history of depression (Bonferroni-corrected P < .05). Depression PGS was the only PGS that significantly associated with both family risk and offspring’s psychopathology, and robustly mediated the impact of family history of depression on several youth psychopathologies including anxiety disorders, suicidal ideation, and any psychiatric disorder (proportions mediated 1.39%-5.87% of the total effect on psychopathology; FDR-corrected P < .05). These findings suggest that increased polygenic risk for depression partially mediates the associations between family risk for depression and offspring psychopathology, showing a genetic basis for intergenerational transmission of depression. Future approaches that combine assessments of family risk with polygenic profiles may offer a more accurate method for identifying children at elevated risk.
A Novel Feature Selection Evolutionary Computation Framework for Privacy Preservation
Authors: Duan Duan-Ting , Sun Bing , Li Jian-Yu , Yang Qiang , Liu Xiao-Fang 
Published: July 2024

Abstract

The application of feature selection to identify important features in data processing is critical for enhancing the efficiency of learning models, which not only reduces the training duration of the models but also enhances their interpretability. Evolutionary Computation (EC) is one of the most powerful and efficient feature selection methods, capable of identifying representative subsets of features through evolutionary processes in a reasonable computational time. However, with the increasing social and legal focus on privacy, the requirement to perform effective data analysis without revealing sensitive personal information has become a growing concern, posing new challenges to existing feature selection methods. To efficiently select features from privacy-sensitive data, this paper introduces a novel feature selection framework for EC to balance data privacy and computational efficiency. Specifically, a privacy-preserving framework is proposed that employs a rank-based cryptographic function to return encrypted fitness values rather than specific values, thereby ensuring privacy by preventing access to actual data information. Then, an elite population learning strategy is introduced to speed up EC algorithm convergence and prevent trapping in local optima. Finally, by integrating the privacy-preserving framework with enhanced EC algorithms, this paper introduces new methods for feature selection in privacy-sensitive data, and experiments on public datasets demonstrate that our algorithms not only preserve privacy but also enhance feature selection efficiency.
A groundbreaking anal preservation theory: sufficient pelvic floor muscle function can retain significant defecation function after in-situ anal reconstruction surgery
Authors: Liu Guoyan , Lei YiHui , Lin Li 
Published: July 2024

Abstract

Currently, patients with ultra-low rectal cancer/anal canal cancer usually undergo an abdominoperineal resectionwith sigmoid colostomy. Patients commonly experience a poor quality of life post-surgery, often feeling that their dignity has been compromised. Some patients are even willing to forego treatment rather than lose their anus. To explore the patients with ultra-low rectal/anal canal cancer who have well function of pelvic floor muscle before surgery can still retain clinically significant defecation function after undergoing combined procedures of partial pelvic floor muscle resection and in-situ anal reconstruction. After 6 months postoperatively,patient 1’s Wexner scores was 9, and she reported effective control over bowel movements. After 24 months postoperatively, the Wexner scores was 12 for patient 2, and 16 for patient 3. Patient 2 can effectively suppress fecal discharge, experiencing only 2-3 episodes of fecal incontinence per week. Patient 3 can perceive the urge for defecation and can consciously inhibit bowel movement for approximately 20s. Patients who have well-functioning pelvic floor muscle can undergo combined procedures of partial pelvic floor muscle resection and in-situ anal reconstruction.
Predicting the risk of postoperative death risk in Acute Type A Aortic Dissection: development and evaluation of a new predictive nomogram
Authors: Ying Chenxi , Wan Zhedong , Chen Ruoshi , Li Weidong , Chen Xin 
Published: July 2024

Abstract

Background
Acute type A aortic dissection (ATAAD) is an emergency condition characterized by severe chest pain and back pain, with rapid disease progression and a very high mortality rate. The current methods for predicting postoperative mortality rate in acute type A aortic dissection are inadequate, necessitating the urgent need for new prediction methods.
Methods
This study is a retrospective analysis of 309 patients with ATAAD in The First Affiliated Hospital Zhejiang University of Medicine. By utilizing the LASSO and logistic regression analysis, we have developed a novel predictive model for postoperative mortality rate. The model incorporates factors such as platelet count (PLT), lactic acid (LA), hydroxybutyrate dehydrogenase (HBDH) , activated partial thromboplastin time (APTT) , deep hypothermic circulatory arrest (DHCA) time to predict the risk of mortality in patients.
Results
The predictive nomogram included predictors such as PLT, LA, HBDH, APTT, and DHCA time. With a C-index of 0.9787, the model demonstrated good discrimination power, calibration, and ROC curve. It was able to maintain a high C-index value of 0.984 even during interval verification.
Conclusions
We have developed and validated a novel predictive model for assessing postoperative mortality risk in Chinese ATAAD patients. This predictive tool demonstrates good discriminatory ability and calibration, which can assist clinicians in making more accurate risk assessments and devising personalized treatment plans.
Examining Dimensions of Career Intentions: Insights From Medical and Nursing Students at a Private Not-for Profit University in Vietnam
Authors: Ha Minh Thuy , Dao Huy Cu , Nguyen Hoa Huyen , Nguyen Hoang Long , Le Phuoc 
Published: July 2024

Abstract

In undergraduate health professions education, the primary goal is to prepare students with the skills and knowledge for employment and to foster a motivated future health workforce. Studies show that job satisfaction is linked to educational satisfaction, and well-designed transition programs and clinical exposure are crucial for smooth transitions from academia to the professional world. Through a mixed-methods approach incorporating both quantitative surveys and qualitative interviews, this study aims to provide further insights into students' career aspirations and the underlying determinants for health professions students in Vietnam. In phase one, 198 respondents were surveyed, equivalent to 77% of recipients, providing demographic data and quantitative insight into career preferences. Phase two consisted of in-depth individual interviews with 11 students to explore the nuanced factors influencing their career intentions. The results reveal a diverse range of career aspirations among students, with a predominant interest in clinical practice, focusing on surgery, internal medicine and pediatrics. Notably, 22.7% (n = 45) of students aspire to practice overseas, while nearly 31.4% (n=62) have yet to decide between local or overseas practice. The study also reveals a need to improve career counseling support, as a significant portion (70.7%, n=140) of participants feel they have not received adequate assistance in this area. Factors such as personal interest, family influence, financial considerations, societal appreciation, and mentorship emerged as significant influences on students' career decisions. The study provides insights for educational institutions and policymakers to enhance career guidance and support services, identify the needs of counselling and mentorship program, thereby facilitating the successful transition of students into their chosen healthcare professions.
Flubendazole presents anti-tumor effects by promoting cell cycle arrest and inhibiting the invadopodia in pancreatic cancer
Authors: Zhao Pengcheng , Wang Zihe , Huang Xing , Xue Kang , Liu Xiaofeng , Tian Bole 
Published: July 2024

Abstract

Pancreatic ductal adenocarcinoma (PDAC) is characterised by its high aggressive biological tumor behavior leading to a poor prognosis. The existing chemotherapy regimes have considerable limitations such as drug resistance and serious adverse effects. Flubendazole is an antihelmintic drug with highly safety that is recently reported to be a potential anti-tumor agent in various types of human cancer cells. We conducted a series of assays to explore its role in PDAC, like CCK8 assays, transwell-migration and invasion assays. In addition, we constructed the invadopodia model in vitro to investigate the effect of flubendazole on invadopodia. We found that flubendazole could inhibit the viability of PDAC cells dose-dependently and time-dependently. It also caused G2/M arrest by disrupting the microtubule and also induce apoptosis. The migration of PDAC cells was attenuated and could be partly explained by the disruption of EMT caused by flubendazole. Besides, the invasion was weakened by flubendazole and the number of cells with mature invadopodia was also decreased. Moreover, it interfered the formation and maturation of invadopodia by inhibiting PI3K/Akt pathway and Src-mediated Tks5 phosphorylation, and thus inhibit the metastasis of PDAC cells. Due to its high safety, it may provide a novel insight for the prevention and treatment of pancreatic cancer metastasis.
Evaluation of easterly wave disturbances over the tropical South Atlantic in CMIP6 models
Authors: Cavalcante Lucas , Gomes Helber , Hodges Kevin , Ray Pallav , Herdies Dirceu , Barbosa Henrique , Gonçalves Weber , Silva Maria Cristina , Brito José Ivaldo , Nobre João Pedro , Lyra Matheus , Baltaci Hakki 
Published: July 2024

Abstract

This study assesses the performance of the latest phase of Coupled Model Intercomparison Project (CMIP6) models in simulating easterly wave disturbances (EWD) over the tropical South Atlantic (TSA) impacting northeast Brazil (NEB). Initially, we evaluate simulated precipitation from 17 historical CMIP, 16 AMIP, 7 hist-1950, and 10 highresSST-present models against the Global Precipitation Climatology Project (GPCP) dataset to identify models that accurately reproduce the spatial and temporal precipitation patterns in the study region. The ensemble's spatial analysis demonstrates their capability in reproducing annual and seasonal precipitation climatology. However, models underestimate precipitation intensity along NEB's coast while overestimating it in TSA and NEB's north. Model uncertainties tend to be greater with higher latitudes. The models represented the annual cycle in all subareas within the study region, particularly from July to October, albeit with a greater spread in the first half of the year, especially over the Intertropical Convergence Zone (ITCZ). Based on it, three top-performing models from each ensemble were selected for EWD evaluation. The automatic tracking algorithm for EWDs showed the model's ability to represent mean values of EWD lifetime (~ 6 days) and phase speed (~ 7 m s-1) as found in ERA5 reanalysis. However, they failed to capture EWD's interannual variability or climatological mean frequency. Despite CMIP6 model weaknesses, they accurately identified two primary EWD genesis regions: one over the TSA and another near the West African coast. Overall, CMIP6 models, particularly atmospheric and high-resolution models (HighResMIP), effectively captured precipitation climatology and EWD characteristics over NEB and the adjacent TSA.