bluuebunny/crossref_metadata_2025_split huggingface dataset:
« [L]a vie ne se rejoignait pas à elle-même »
Authors: Samson Véronique 
Published: October 2013

Si la première moitié du XXe siècle pense l’aventure romanesque comme une prolifération des possibles, la seconde verrait apparaître les limites de cette conception héritée de Jacques Rivière. En prenant comme cas de figure Un balcon en forêt (1958), le dernier roman de Julien Gracq, cette étude suggère que l’expérience de la « drôle de guerre » aura engendré, au coeur de la carrière littéraire de l’écrivain, une crise toute paradoxale, issue du désir de maintenir les possibles ouverts pour son personnage dans un monde devenu inhabitable.
Biologic Versus Nonbiologic Mesh in Ventral Hernia Repair: A Systematic Review and Meta‐analysis
Authors: Darehzereshki Ali , Goldfarb Melanie , Zehetner Joerg , Moazzez Ashkan , Lipham John C. , Mason Rodney J. , Katkhouda Namir 
Published: October 2013

AbstractBackgroundThe current standard of treatment for most ventral hernias is a mesh‐based repair. Little is known about the safety and efficacy of biologic versus nonbiologic grafts. A meta‐analysis was performed to examine two primary outcomes: recurrence and wound complication rates.MethodsElectronic databases and reference lists of relevant articles were systematically searched for all clinical trials and cohort studies published between January 1990 and January 2012. A total of eight retrospective studies, with 1,229 patients, were included in the final analysis.ResultsBiologic grafts had significantly fewer infectious wound complications (p < 0.00001). However, the recurrence rates of biologic and nonbiologic mesh were not different. In subgroup analysis, there was no difference in recurrence rates and wound complications between human‐derived and porcine‐derived biologic grafts.ConclusionsUse of biologic mesh for ventral hernia repair results in less infectious wound complications but similar recurrence rates compared to nonbiologic mesh. This supports the application of biologic mesh for ventral hernia repair in high‐risk patients or patients with a previous history of wound infection only when the significant additional cost of these materials can be justified and synthetic mesh is considered inappropriate.
Immunological Changes After Minimally Invasive or Conventional Esophageal Resection for Cancer: A Randomized Trial
Authors: Maas K. W. , Biere S. S. A. Y. , van Hoogstraten I. M. W. , van der Peet D. L. , Cuesta M. A. 
Published: October 2013

AbstractBackgroundThis study was performed as a substudy analysis of a randomized trial comparing conventional open esophagectomy [open surgical technique (OE)] by thoracotomy and laparotomy with minimally invasive esophagectomy [minimally invasive procedure (MIE)] by thoracoscopy and laparoscopy. This additional analysis focuses on the immunological changes and surgical stress response in these two randomized groups of a single center.
MethodsPatients with a resectable esophageal cancer were randomized to OE (n = 13) or MIE (n = 14). All patients received neoadjuvant chemoradiotherapy. The immunological response was measured by means of leukocyte counts, HLA‐DR expression on monocytes, the acute‐phase response by means of C‐reactive protein (CRP), interleukin‐6 (IL‐6), and interleukin‐8 (IL‐8), and the stress response was measured by cortisol, growth hormone, and prolactin. All parameters were determined at baseline (preoperatively) and 24, 72, 96, and 168 h postoperatively.
ResultsSignificant differences between the two groups were seen in favor of the MIE group with regard to leukocyte counts, IL‐8, and prolactin at 168 h (1 week) postoperatively. For HLA‐DR expression, IL‐6, and CRP levels, there were no significant differences between the two groups, although there was a clear rise in levels upon operation in both groups.ConclusionIn this substudy of a randomized trial comparing minimally invasive and conventional open esophagectomies for cancer, significantly better preserved leukocyte counts and IL‐8 levels were observed in the MIE group compared to the open group. Both findings can be related to fewer respiratory infections found postoperatively in the MIE group. Moreover, significant differences in the prolactin levels at 168 h after surgery imply that the stress response is better preserved in the MIE group. These findings indicate that less surgical trauma could lead to better preserved acute‐phase and stress responses and fewer clinical manifestations of respiratory infections.
Defining Anatomical Landmarks for Robotic Facelift Thyroidectomy
Authors: Singer Michael C. , Heffernan Andrew , Terris David J. 
Published: October 2013

AbstractBackgroundRobotic facelift thyroidectomy (RFT) is a straightforward remote access thyroidectomy technique. While the anatomy encountered during RFT is well known to surgeons, the vector of approach during this technique may be less familiar. In order to facilitate safe and efficient performance of RFT, the relationships of key anatomical landmarks associated with this technique were determined.MethodsEight anatomical dissections were performed in cadavers and included performance of RFT and definition of discrete anatomical relationships. Morphologic assessments of the great auricular nerve (GAN), omohyoid (OH) muscle, inferior constrictor (IC) muscle, and recurrent laryngeal nerve (RLN) were conducted.ResultsThe mean distance from the incision apex to the anterior and posterior aspects of the GAN were 3.8 ± 1.2 and 7.7 ± 0.8 cm. From the apex of the incision to the OH muscle was 11.1 ± 1.7 cm on average. The OH muscle was located 1.3 ± 0.5 cm inferior to an axial line drawn through the inferior aspect of the thyroid notch. The anterior branch of the RLN was identified coursing deep to the inferior margin of the IC muscle a mean of 1.2 ± 0.2 cm lateral to the origin of this muscle on the cricoid cartilage.ConclusionsCharacterization of the key anatomical landmarks of the lateral neck and thyroid compartment associated with RFT, including the GAN, OH muscle, and RLN, allows for rapid recognition of these critical structures during this operation. Surgeons learning this approach should be familiar with these relationships.
The spectrum of musculoskeletal problems in lipomyelomeningocele
Authors: Segal Lee S. , Czoch Wojciech , Hennrikus William L. , Wade Shrader M. , Kanev Paul M. 
Published: October 2013

Purpose Patients with lipomyelomeningocele (LMMC) represent a unique population within the spectrum of spinal dysraphism. The natural history of LMMC remains poorly defined. The description and prevalence of the presenting orthopaedic clinical signs and symptoms for LMMC have been infrequent and often documented only in general terms. The goal of this study is to define the patterns and prevalence of presenting clinical musculoskeletal signs and symptoms in LMMC patients. Methods This study was a retrospective review of charts of all patients identified as having LMMC in our spina bifida clinic. Patient charts with incomplete data or diagnoses other than LMMC were excluded from the analysis. Data collected included age at initial tethered cord release (TCR); repeat TCR; limb length discrepancy; foot deformities; asymmetry of motor and sensory deficits; presence of scoliosis; orthotic needs; assistive devices; functional status. Results We identified 32 patients with LMMC (21 female and 11 male patients). The majority of patients had their primary TCR by ≤1 year of age (59 %), with 22 and 19 % having primary TCR at ages 1–15 and >15 years, respectively. Fifteen patients had at least one repeat TCR, with ten of these having more than one repeat TCR. A significant relationship was noted between low back/radicular pain and repeat TCR ( p < 0.001). Ten patients (31%) had a limb length discrepancy of >2.5 cm, and 53 % of patients had asymmetric involvement. Nine patients (28 %) had scoliosis of whom only one required operative treatment. Fifteen patients had foot deformities. Thirteen patients (41 %) had two or more orthopaedic procedures in addition to other neurologic or urologic procedures. Conclusion The presenting musculoskeletal clinical signs and symptoms in patients with LMMC are uniquely different in terms of both pattern and frequency compared to myelomeningocele and other forms of spinal dysraphism. We noted a high prevalence of asymmetrical involvement, a high operative burden, and a high rate of repeat symptomatic tethered cord syndrome requiring TCR. As previously noted by others, TCR in LMMC does not prevent long-term functional deterioration. These findings may be important to our colleagues providing counsel to their patients with LMMC and to their families.
Inclusion of glycerol in forage diets increases methane production in a rumen simulation technique system
Authors: Avila-Stagno Jorge , Chaves Alexandre V. , O. Ribeiro Gabriel , Ungerfeld Emilio M. , McAllister Tim A. 
Published: October 2013

We hypothesised that the inclusion of glycerol in the forage diets of ruminants would increase the proportion of propionate produced and thereby decreasein vitroCH4production. This hypothesis was examined in the present study using a semi-continuous fermentation system (rumen simulation technique) fed a brome hay (8·5 g) and maize silage (1·5 g) diet with increasing concentrations (0, 50, 100 and 150 g/kg DM) of glycerol substituted for maize silage. Glycerol linearly increased total volatile fatty acids production (P< 0·001). Acetate production was quadratically affected (P= 0·023) and propionate and butyrate production was linearly increased (P< 0·001). Glycerol linearly increased (P= 0·011) DM disappearance from hay and silage. Crude protein disappearance from hay was not affected (P= 0·789), but that from silage was linearly increased (P< 0·001) with increasing glycerol concentrations. Neutral-detergent fibre (P= 0·040) and acid-detergent fibre (P= 0·031) disappearance from hay and silage was linearly increased by glycerol. Total gas production tended to increase linearly (P= 0·061) and CH4concentration in gas was linearly increased (P< 0·001) by glycerol, resulting in a linear increase (P< 0·001) in mg CH4/g DM digested. Our hypothesis was rejected as increasing concentrations of glycerol in a forage diet linearly increased CH4production in semi-continuous fermenters, despite the increases in the concentrations of propionate. In conclusion, this apparent discrepancy is due to the more reduced state of glycerol when compared with carbohydrates, which implies that there is no net incorporation of electrons when glycerol is metabolised to propionate.
SPECTRA AND CATENARITY OF MULTI-PARAMETER QUANTUM SCHUBERT CELLS
Authors: YAKIMOV MILEN 
Published: October 2013

AbstractWe study the ring theory of the multi-parameter deformations of the quantum Schubert cell algebras obtained from 2-cocycle twists. This is a large family, which extends the Artin–Schelter–Tate algebras of twisted quantum matrices. We classify set theoretically the spectra of all such multi-parameter quantum Schubert cell algebras, construct each of their prime ideals by contracting from explicit normal localizations and prove formulas for the dimensions of their Goodearl–Letzter strata for base fields of arbitrary characteristic and all deformation parameters that are not roots of unity. Furthermore, we prove that the spectra of these algebras are normally separated and that all such algebras are catenary.
The neuroanatomy of subthreshold depressive symptoms in Huntington's disease: a combined diffusion tensor imaging (DTI) and voxel-based morphometry (VBM) study
Authors: Sprengelmeyer R. , Orth M. , Müller H.-P. , Wolf R. C. , Grön G. , Depping M. S. , Kassubek J. , Justo D. , Rees E. M. , Haider S. , Cole J. H. , Hobbs N. Z. , Roos R. A. C. , Dürr A. , Tabrizi S. J. , Süssmuth S. D. , Landwehrmeyer G. B. 
Published: October 2013

BackgroundDepressive symptoms are prominent psychopathological features of Huntington's disease (HD), making a negative impact on social functioning and well-being.MethodWe compared the frequencies of a history of depression, previous suicide attempts and current subthreshold depression between 61 early-stage HD participants and 40 matched controls. The HD group was then split based on the overall HD group's median Hospital Anxiety and Depression Scale-depression score into a group of 30 non-depressed participants (mean 0.8,s.d. = 0.7) and a group of 31 participants with subthreshold depressive symptoms (mean 7.3,s.d. = 3.5) to explore the neuroanatomy underlying subthreshold depressive symptoms in HD using voxel-based morphometry (VBM) and diffusion tensor imaging (DTI).ResultsFrequencies of history of depression, previous suicide attempts or current subthreshold depressive symptoms were higher in HD than in controls. The severity of current depressive symptoms was also higher in HD, but not associated with the severity of HD motor signs or disease burden. Compared with the non-depressed HD group DTI revealed lower fractional anisotropy (FA) values in the frontal cortex, anterior cingulate cortex, insula and cerebellum of the HD group with subthreshold depressive symptoms. In contrast, VBM measures were similar in both HD groups. A history of depression, the severity of HD motor signs or disease burden did not correlate with FA values of these regions.ConclusionsCurrent subthreshold depressive symptoms in early HD are associated with microstructural changes – without concomitant brain volume loss – in brain regions known to be involved in major depressive disorder, but not those typically associated with HD pathology.
A survey of skeletal elements in the orbit of Pseudosuchia and the origin of the crocodylian palpebral
Authors: Nesbitt Sterling J. , Turner Alan H. , Weinbaum Jonathan C. 
Published: October 2013

ABSTRACTOssified skeletal elements within the orbit, such as scleral ossicles, palpebrals, supraorbitals and sesamoids, are widespread across Reptilia, including extant members of Crocodylia, Aves, Squamata and Chelonia. Extant crocodylians lack scleral ossicles, but have a unique palpebral that has recently been shown, through developmental studies, to be an osteoderm in the upper eyelid. Here, we examine the diversity and disparity of the crocodylian palpebral in extant members of Crocodylia and, through the fossil record, trace the origin and evolutionary history of the element throughout Pseudosuchia (all archosaurs more closely related to crocodylians than avians). We show that the crocodylian palpebral originated outside of Crocodylomorpha in early pseudosuchian groups (e.g. Aetosauria, Loricata) and that scleral ossicles are lost in nearly all groups of pseudosuchians, but appear in poposauroids, at least one early crocodylomorph, and some partially or fully marine Crocodyliformes (e.g. thalattosuchians). The morphology and number of palpebrals differs across Crocodyliformes; the presence of two palpebrals is plesiomorphic, but this is reduced to one by Crocodylia. We further recommend the restriction of the term palpebral to the structure in crocodylians and their homologues, but not to the structure in ornithischian dinosaurs.
Macrophages: Gatekeepers of Tissue Integrity
Authors: Lavin Yonit , Merad Miriam 
Published: October 2013

Abstract
Macrophages form a heterogeneous group of hematopoietic cells that reside in tissues, where they are required to maintain organ integrity. Tissue macrophages contribute to tissue formation, metabolism, homeostasis, and repair. They have a unique ability to sense and respond to tissue damage. They serve as the first line of defense during infection and help promote immune tolerance in the steady state. Although most tissue macrophages share a high phagocytic and degradative potential, they are heterogeneous in origin, as well as in homeostatic function and response to insults. Here, we will discuss recent developments in our understanding of the origin of tissue macrophages and their functional specialization in tissues. Cancer Immunol Res; 1(4); 201–9. ©2013 AACR.
High-Latitude Atmospheric Motion Vectors from Composite Satellite Data
Authors: Lazzara Matthew A. , Dworak Richard , Santek David A. , Hoover Brett T. , Velden Christopher S. , Key Jeffrey R. 
Published: October 2013

AbstractAtmospheric motion vectors (AMVs) are derived from satellite-observed motions of clouds and water vapor features. They provide crucial information in regions void of conventional observations and contribute to forecaster diagnostics of meteorological conditions, as well as numerical weather prediction. AMVs derived from geostationary (GEO) satellite observations over the middle latitudes and tropics have been utilized operationally since the 1980s; AMVs over the polar regions derived from low‐earth (polar)‐orbiting (LEO) satellites have been utilized since the early 2000s. There still exists a gap in AMV coverage between these two sources in the latitude band poleward of 60° and equatorward of 70° (both hemispheres). To address this AMV gap, the use of a novel approach to create image sequences that consist of composites derived from a combination of LEO and GEO observations that extend into the deep middle latitudes is explored. Experiments are performed to determine whether the satellite composite images can be employed to generate AMVs over the gap regions. The derived AMVs are validated over both the Southern Ocean/Antarctic and the Arctic gap regions over a multiyear period using rawinsonde wind observations. In addition, a two-season numerical model impact study using the Global Forecast System indicates that the assimilation of these AMVs can improve upon the control (operational) forecasts, particularly during lower-skill (dropout) events.
A Compressible Nonhydrostatic Cell-Integrated Semi-Lagrangian Semi-Implicit Solver (CSLAM-NH) with Consistent and Conservative Transport
Authors: Wong May , Skamarock William C. , Lauritzen Peter H. , Klemp Joseph B. , Stull Roland B. 
Published: October 2013

AbstractA cell-integrated semi-Lagrangian (CISL) semi-implicit nonhydrostatic solver for the fully compressible moist Euler equations in two-dimensional Cartesian (x–z) geometry is presented. The semi-implicit CISL solver uses the inherently conservative semi-Lagrangian multitracer transport scheme (CSLAM) and a new flux-form semi-implicit formulation of the continuity equation that ensures numerically consistent transport. The flux-form semi-implicit formulation is based on a recent successful approach in a shallow-water equations (SWE) solver (CSLAM-SW). With the new approach, the CISL semi-implicit nonhydrostatic solver (CSLAM-NH) is able to ensure conservative and consistent transport by avoiding the need for a time-independent mean reference state. Like its SWE counterpart, the nonhydrostatic solver presented here is designed to be similar to typical semi-Lagrangian semi-implicit schemes, such that only a single linear Helmholtz equation solution and a single call to CSLAM are required per time step. To demonstrate its stability and accuracy, the solver is applied to a set of three idealized test cases: a density current (dry), a gravity wave (dry), and a squall line (moist). A fourth test case shows that shape preservation of passive tracers is ensured by coupling the semi-implicit CISL formulation with existing shape-preserving filters. Results show that CSLAM-NH solutions compare well with other existing solvers for the three test cases, and that it is shape preserving.
Evaluation of age-dependent susceptibility in calves infected with two doses of Mycobacterium avium subspecies paratuberculosis using pathology and tissue culture
Authors: Mortier Rienske AR , Barkema Herman W , Bystrom Janet M , Illanes Oscar , Orsel Karin , Wolf Robert , Atkins Gordon , De Buck Jeroen 
Published: October 2013

Abstract
The longstanding assumption that calves of more than 6 months of age are more resistant to Mycobacterium avium subspecies paratuberculosis (MAP) infection has recently been challenged. In order to elucidate this, a challenge experiment was performed to evaluate age- and dose-dependent susceptibility to MAP infection in dairy calves. Fifty-six calves from MAP-negative dams were randomly allocated to 10 MAP challenge groups (5 animals per group) and a negative control group (6 calves). Calves were inoculated orally on 2 consecutive days at 5 ages: 2 weeks and 3, 6, 9 or 12 months. Within each age group 5 calves received either a high – or low – dose of 5 × 109 CFU or 5 × 107 CFU, respectively. All calves were euthanized at 17 months of age. Macroscopic and histological lesions were assessed and bacterial culture was done on numerous tissue samples. Within all 5 age groups, calves were successfully infected with either dose of MAP. Calves inoculated at < 6 months usually had more culture-positive tissue locations and higher histological lesion scores. Furthermore, those infected with a high dose had more severe scores for histologic and macroscopic lesions as well as more culture-positive tissue locations compared to calves infected with a low dose. In conclusion, calves to 1 year of age were susceptible to MAP infection and a high infection dose produced more severe lesions than a low dose.
Advances in the REDCAT software package
Authors: Schmidt Chris , Irausquin Stephanie J , Valafar Homayoun 
Published: October 2013

Abstract

Background
Residual Dipolar Couplings (RDCs) have emerged in the past two decades as an informative source of experimental restraints for the study of structure and dynamics of biological macromolecules and complexes. The REDCAT software package was previously introduced for the analysis of molecular structures using RDC data. Here we report additional features that have been included in this software package in order to expand the scope of its analyses. We first discuss the features that enhance REDCATs user-friendly nature, such as the integration of a number of analyses into one single operation and enabling convenient examination of a structural ensemble in order to identify the most suitable structure. We then describe the new features which expand the scope of RDC analyses, performing exercises that utilize both synthetic and experimental data to illustrate and evaluate different features with regard to structure refinement and structure validation.

Results
We establish the seamless interaction that takes place between REDCAT, VMD, and Xplor-NIH in demonstrations that utilize our newly developed REDCAT-VMD and XplorGUI interfaces. These modules enable visualization of RDC analysis results on the molecular structure displayed in VMD and refinement of structures with Xplor-NIH, respectively. We also highlight REDCAT’s Error-Analysis feature in reporting the localized fitness of a structure to RDC data, which provides a more effective means of recognizing local structural anomalies. This allows for structurally sound regions of a molecule to be identified, and for any refinement efforts to be focused solely on locally distorted regions.

Conclusions
The newly engineered REDCAT software package, which is available for download via the WWW from http://ifestos.cse.sc.edu, has been developed in the Object Oriented C++ environment. Our most recent enhancements to REDCAT serve to provide a more complete RDC analysis suite, while also accommodating a more user-friendly experience, and will be of great interest to the community of researchers and developers since it hides the complications of software development.