bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of in‐hospital bleeding according to the bleeding academic research consortium classification on the long‐term adverse outcomes in patients undergoing percutaneous coronary intervention
Authors: Yoon Yong‐Hoon , Kim Young‐Hak , Kim Seon‐Ok , Lee Jong‐Young , Park Duk‐Woo , Kang Soo‐Jin , Lee Seung‐Whan , Lee Cheol Whan , Park Seong‐Wook , Park Seung‐Jung 
Published: November 2013

ObjectivesThe aim of this study was to assess the impact of bleeding after percutaneous coronary intervention (PCI) with drug‐eluting stents on long‐term clinical events according to the newly proposed Bleeding Academic Research Consortium (BARC) classification.BackgroundCurrent evidence about the impact of the BARC classification is limited.MethodsOut of a total of 6,166 patients who underwent PCI in a prospective IRIS‐DES registry, the impact of in‐hospital bleeding defined as the BARC classification on major adverse cardiovascular events (MACE) comprising death, myocardial infarction (MI), or stroke was analyzed.ResultsIn‐hospital bleeding occurred in 235 patients (3.8%) according to BARC classification. During the 2‐year follow‐up, MACE occurred in 599 patients (9.7%). The 2‐year incidence of MACE was significantly higher in patients with bleeding (16.7% vs. 8.3%; adjusted hazard ratio [HR], 1.6; 95% confidence interval [CI], 1.2–2.3; P = 0.002) than in those without bleeding. We observed a higher risk of MI (12.4% vs. 6.4%; adjusted HR, 1.7; 95% CI, 1.2–2.6, P = 0.005), stroke (3.0% vs. 0.6%; adjusted HR, 2.9; 95% CI, 1.4–6.2, P = 0.005) in patients with bleeding. Death (3.8% vs. 1.6%; adjusted HR, 1.6; 95% CI, 0.9–3.0, P = 0.120) and target vessel revascularization (4.3% vs. 1.9%; adjusted HR, 1.6; 95% CI, 0.9–2.9, P = 0.108) were statistically insignificant. Incidence, adjusted HR and P‐value were similar between BARC and TIMI classification.ConclusionsIn‐hospital bleeding events according to the newly proposed BARC definition were significantly associated with an increased risk of adverse long‐term events in patients undergoing PCI with drug‐eluting stents. © 2014 Wiley Periodicals, Inc.
Tuning Hydrodesulfurization Active‐Phase Dispersion using Optimized Mesoporous Titania‐Doped Silica Supports
Authors: Nguyen Dinh Minh Tuan , Rajbhandari Prashant , Lancelot Christine , Blanchard Pascal , Lamonier Carole , Bonne Magali , Royer Sébastien , Dumeignil Franck , Payen Edmond 
Published: November 2013

AbstractSolids composed of TiO2 nano‐crystallites (10–40 wt %) dispersed in an SBA‐15 matrix were synthesised and used as hydrodesulfurisation (HDS) active‐phase supports. Well‐dispersed polymolybdate species were detected by Raman spectroscopy on all the CoMo‐based oxidic precursors. Undesirable bulk CoMoO4 mixed oxide was also detected on the surface of low‐TiO2‐content materials, which suggests the enhancement of the Mo oxidic species dispersion as a result of the presence of TiO2. After activation under H2/H2S, the obtained catalysts were tested in the HDS of thiophene. An optimum conversion was observed for the catalyst supported on the solid that contained 20 wt % TiO2, which outperformed the homologous samples supported on TiO2 and SBA‐15. This clearly highlights the beneficial effect of using such nano‐TiO2‐SBA‐15 composite supports, in which SBA‐15 confers adequate textural properties to the system, and the active phase benefits from the dispersive effect of TiO2.
Facile Access to cis‐2,6‐Disubstituted Tetrahydropyrans by Palladium‐Catalyzed Decarboxylative Allylation: Total Syntheses of (±)‐Centrolobine and (+)‐Decytospolides A and B
Authors: Zeng Jing , Tan Yu Jia , Ma Jimei , Leow Min Li , Tirtorahardjo Davin , Liu Xue‐Wei 
Published: November 2013

Abstractcis‐2,6‐Tetrahydropyran is an important structural skeleton of bioactive natural products. A facile synthesis of cis‐2,6‐disubstituted‐3,6‐dihydropyrans as cis‐2,6‐tetrahydropyran precursors has been achieved in high regio‐ and stereoselectivity with high yields. This reaction involves a palladium‐catalyzed decarboxylative allylation of various 3,4‐dihydro‐2H‐pyran substrates. Extending this reaction to 1,2‐unsaturated carbohydrates allowed the achievement of challenging β‐C‐glycosylation. Based on this methodology, the total syntheses of (±)‐centrolobine and (+)‐decytospolides A and B were achieved in concise steps and overall high yields.
Modelling strategies for emulsification in industrial practice
Authors: Janssen Jo J.M. , Hoogland Hans 
Published: November 2013

AbstractEmulsification modelling has received quite some attention in academic literature. Given the importance of modelling for process optimisation and scale‐up, it is a relevant question to what extent this work is used in industrial practice. In this paper we address this question based on Unilever experience, mainly for food and personal care emulsions. These products often have a high droplet fraction and/or a non‐Newtonian rheology, and the geometry of the emulsification equipment is often complex. This limits the use of advanced methods like multiphase computational fluid dynamics (CFD). Most of the practical work is still based on semi‐empirical models.
Discovery of Potent HDAC Inhibitors Based on Chlamydocin with Inhibitory Effects on Cell Migration
Authors: Wang Shimiao , Li Xiaohui , Wei Yingdong , Xiu Zhilong , Nishino Norikazu 
Published: November 2013

AbstractThe histone deacetylase (HDAC) family is a promising drug target class owing to the importance of these enzymes in a variety of cellular processes. Docking studies were conducted to identify novel HDAC inhibitors. Subtle modifications in the recognition domain were introduced into a series of chlamydocin analogues, and the resulting scaffolds were combined with various zinc binding domains. Remarkably, cyclo(L‐Asu(NHOH)‐L‐A3mc6c‐L‐Phe‐D‐Pro, compound 1 b), with a methyl group at positions 3 or 5 on the aliphatic ring, exhibited better antiproliferative effects than trichostatin A (TSA) against MCF‐7 and K562 cell lines. In addition to cell‐cycle arrest and apoptosis, cell migration inhibition was observed in cells treated with compound 1 b. Subsequent western blot analysis revealed that the balance between matrix metalloproteinase 2 (MMP2) and tissue inhibitors of metalloproteinase 1 (TIMP1) determines the degree of metalloproteinase activity in MCF‐7 cells, thereby regulating cell migration. The improved inhibitory activity imparted by altering the hydrophobic substitution pattern at the bulky cap group is a valuable approach in the development of novel HDAC inhibitors.
Brightness scaling according to gamut relativity
Authors: Vladusich Tony 
Published: November 2013

AbstractBrill and Carter [Color Res Appl (DOI:10.1002/col21777)] rekindle the question of whether brightness scaling is better approximated by a log or power function, proposing on theoretical and empirical grounds that the log function is the correct choice. This note provides a new twist to this debate in terms of a recently introduced theory of brightness and lightness perception, called gamut relativity. The theory reconciles the log and power function formulations and approximately predicts the weight/exponent values associated with these functions. The theory provides, moreover, a unified and testable approach to human performance in brightness magnitude estimation, discrimination and matching tasks. © 2013 Wiley Periodicals, Inc. Col Res Appl, 39, 463–465, 2014
A new approach to designing firewall based on multidimensional matrix
Authors: Cheng Yuzhu , Wang Weiping , Min Geyong , Wang Jianxin 
Published: November 2013

SummaryFirewalls are crucial elements to enhance network security by examining the field value of every packet and decide whether to accept or discard the packet according to the firewall policy. However, the design of firewall policies, especially for enterprise networks, is complex and error‐prone. This paper aims to propose an effective firewall design method to ensure the consistency, compactness and completeness of firewall rules. Specifically, we develop a new designing model, namely firewall design matrix, and the corresponding construction algorithm for mapping firewall rules to firewall design matrix. A firewall generation algorithm is proposed to generate the target firewall rules that are equivalent to the original ones while maintaining the completeness. Theoretical proof and extensive experiments on both real‐world and synthetic firewalls are conducted to evaluate the performance of the proposed method. The results demonstrate that it can achieve a high compression ratio efficiently while maintaining the firewall rules conflict‐free. Copyright © 2013 John Wiley & Sons, Ltd.
Graphene‐Supported Trimetallic Core–Shell Cu@CoNi Nanoparticles for Catalytic Hydrolysis of Amine Borane
Authors: Meng Xiangyu , Yang Lan , Cao Nan , Du Cheng , Hu Kai , Su Jun , Luo Wei , Cheng Gongzhen 
Published: November 2013

AbstractTrimetallic core–shell Cu@CoNi nanoparticles (NPs) supported on graphene with different compositions are synthesized through a one‐step in situ reduction process by using methylamine borane (MeAB) as a reducing agent. The as‐synthesized Cu‐core/CoNi‐shell NPs are well dispersed on graphene. Among the catalysts studied, Cu0.1@Co0.45Ni0.45/graphene displays the highest catalytic performance toward the hydrolysis of ammonia borane (AB), with a turnover frequency (TOF) value of 15.46 mol H2 min−1(mol catalyst)−1, which is higher than those of most reported non‐noble‐metal‐based NPs, and even higher than many noble‐metal‐based NPs. Additionally, the as‐synthesized Cu0.1@Co0.45Ni0.45/graphene NPs reduced by MeAB exhibit a higher catalytic activity than those reduced by NaBH4 and AB. Furthermore, the as‐prepared NPs have good durability and magnetic recyclability for the hydrolytic dehydrogenation of AB and MeAB.
Design and implementation of switched coil LC‐VCOs in the GHz range using the self‐inductance technique
Authors: Cernoia Federico , Ponton Davide , Palestri Pierpaolo , Thurner Peter , Dalt Nicola Da , Cecco Giulio , Selmi Luca 
Published: November 2013

SummaryThis paper presents the design and implementation of dual‐band LC‐VCOs in the GHz‐range featuring a switched coil LC‐tank. The proposed design exploits the self‐inductance technique. The design of the coil starts from simple considerations and back‐of‐the‐envelope calculations, then electromagnetic simulations are used to optimize the coil layout. The sizing of the switch and its impact on the VCO performance are addressed as well. The VCOs have been implemented in 65 nm CMOS technology. Good correlation between simulated and measured tuning range and phase noise is obtained for all designs, thus confirming the validity and robustness of the design methodology and coil models. Copyright © 2013 John Wiley & Sons, Ltd.
Threat‐related attentional bias in anorexia nervosa
Authors: Dipl‐Psych Ilka Schober , Renwick Beth , de Jong Hannah , Kenyon Martha , Sharpe Helen , Jacobi Corinna , Schmidt Ulrike 
Published: November 2013

ABSTRACTObjectiveAttentional bias (AB) modification treatment targeting general or social anxiety has been recently highlighted as a potential novel approach for the treatment of anorexia nervosa (AN). The purpose of this study was to examine threat‐related AB in patients with ANand healthy control participants (HC) and the relationship between AB and eating disorder and other psychopathology.MethodForty‐nine female outpatients with AN or Eating Disorder Not Otherwise Specified, Anorexia Type (EDNOS‐AN), and 44 female HC completed a dot‐probe task with threat words and a range of self‐report measures assessing eating disorder symptoms and other psychopathology.ResultsThere was no evidence for a differential threat‐related AB in AN patients despite elevated anxiety in this group. The AB‐index, a parameter of the magnitude of attention allocation when two competing stimuli are presented, did not correlate with any of the self‐report measures. However, patients with AN responded significantly more slowly to the probe as compared to controls, regardless of the valence or position of the stimuli.DiscussionThe results suggest that the AB in AN patients may be specific to eating disorder‐relevant anxieties. © 2013 Wiley Periodicals, Inc. (Int J Eat Disord 2014; 47:168–173)
Cannabis withdrawal syndrome: An important diagnostic consideration in adolescents presenting with disordered eating
Authors: Chesney Tyler , Matsos Laura , Couturier Jennifer , Johnson Natasha 
Published: November 2013

ABSTRACTAlthough previously thought to have no withdrawal symptoms, there is now convergent evidence for a cannabis withdrawal syndrome (CWS), criteria for its diagnosis, and evidence of its impact in the adolescent population. Cannabis withdrawal syndrome represents an important and under‐recognized consideration in adolescents with disordered eating. We describe three clinical cases of adolescents presenting to an eating disorders program with primary complaints of gastrointestinal symptoms, food avoidance, and associated weight loss. They did not meet the criteria for an eating disorder, but did fulfill the DSM‐5 criteria for CWS. This report emphasizes the importance of considering the impact of heavy cannabis use in adolescents presenting with gastrointestinal complaints, and eating disorder symptoms, including weight loss. © 2013 Wiley Periodicals, Inc. (Int J Eat Disord 2014; 47:219–223)
Equivalence conditions between linear Lagrangian finite element and node‐centred finite volume schemes for conservation laws in cylindrical coordinates
Authors: De Santis D. , Geraci G. , Guardone A. 
Published: November 2013

SUMMARYA complete set of equivalence conditions, relating the mass‐lumped Bubnov–Galerkin finite element (FE) scheme for Lagrangian linear elements to node‐centred finite volume (FV) schemes, is derived for the first time for conservation laws in a three‐dimensional cylindrical reference. Equivalence conditions are used to devise a class of FV schemes, in which all grid‐dependent quantities are defined in terms of FE integrals. Moreover, all relevant differential operators in the FV framework are consistent with their FE counterparts, thus opening the way to the development of consistent hybrid FV/FE schemes for conservation laws in a three‐dimensional cylindrical coordinate system. The two‐dimensional schemes for the polar and the axisymmetrical cases are also explicitly derived. Numerical experiments for compressible unsteady flows, including expanding and converging shock problems and the interaction of a converging shock waves with obstacles, are carried out using the new approach. The results agree fairly well with one‐dimensional simulations and simplified models. Copyright © 2013 John Wiley & Sons, Ltd.
Use of pilot plant scale continuous fryer to simulate industrial production of potato chips: thermal properties of palm olein blends under continuous frying conditions
Authors: Tarmizi Azmil Haizam Ahmad , Ismail Razali 
Published: November 2013

AbstractBinary blends of palm olein (PO) with sunflower oil (SFO), canola oil (CNO), and cottonseed oil (CSO) were formulated to assess their stability under continuous frying conditions. The results were then compared with those obtained in PO. The oil blends studied were: (1) 60:40 for PO + SFO; (2) 70:30 for PO + CNO; and (3) 50:50 for PO + CSO. The PO and its blends were used to fry potato chips at 180°C for a total of 56 h of operation. The evolution of analytical parameters such as tocols, induction period, color, p‐anisidine value, free fatty acid, smoke point, polar compounds, and polymer compounds were evaluated over the frying time. Blending PO with unsaturated oils was generally proved to keep most qualitative parameters comparable to those demonstrated in PO. Indeed, none of the oils surpassed the legislative limits for used frying. Overall, it was noted that oil containing PO and SFO showed higher resistance toward oxidative and hydrolytic behaviors as compared to the other oil blends.
Above‐zone pressure monitoring and geomechanical analyses for a field‐scale CO2injection project in Cranfield, MS
Authors: Kim Seunghee , Hosseini Seyyed Abolfazl 
Published: November 2013

AbstractPressure and temperature monitoring of an above‐zone monitoring interval (AZMI), as well as of an injection zone (IZ), has been attempted at a field‐scale CO2injection site in Cranfield, MS. Recorded pressure data in the AZMI revealed a certain amount of increase with no evidence of direct fluid flow between the IZ and the AZMI. We therefore attempted to interpret the field‐measurement data from a geomechanical perspective. First, we tried an analytical approach that combined Green's functions with a poroelastic theory that is based on Segall's derivation (1992). The analysis was shown to provide fast first‐order and probabilistic estimation. Next, we attempted a numerical simulation in which fully coupled calculation between fluid flow and poroelasticity was implemented. Numerical‐simulation results using COMSOL matched well with the field data at one monitoring location in the AZMI. However, field data differ from those of a numerical simulation at the other monitoring well. We suggest that field measurement at the other location in the AZMI might be disturbed during the pressure monitoring, based on bottom‐hole pressure records in the IZ and thermal signals. Following the numerical simulation, we discuss the effect of single‐phase fluid flow assumption, observations for thermal effect and pore‐pressure–stress coupling, and desirable resolution of pressure gauges for the optimal utilization of above‐zone pressure monitoring.
Evaluation of coal swelling‐controlled CO2 diffusion processes
Authors: Li Wei , Zhu Jin‐tuo , Cheng Yuan‐ping , Lu Shou‐qing 
Published: November 2013

AbstractCO2 sequestration in deep and unmineable coalbeds is regarded as a viable option for carbon storage. CO2 diffusion is a key parameter determining the effectiveness of sealing CO2 in coal seams. By conducting laboratory tests of coal CO2 desorption and unsteady gas diffusion theory model calculations, the desorption dynamics of Yaojie coal were studied under the condition of constant temperature and varied balance pressures, and the CO2 diffusion coefficient was obtained using the non‐steady diffusion model at different times. The results show that the higher the balance pressure is, the greater the diffusion coefficient is under the same conditions. As the pressure drops, the CO2 diffusion coefficient gradually decreases as time increases, and the mass fraction of desorbed CO2 has a linear relationship with the diffusion coefficient. It was observed that under high pressures, the diffusion coefficient initially increases and then gradually decreases. The non‐steady CO2 diffusion in Yaojie coal is related to CO2‐induced swelling and to the effect of dissolved CO2 on the coal's structures and properties, especially under high‐pressure conditions. The glass transition of coal containing CO2 may be the governing factor leading to the nonlinear diffusion of CO2 in coal.
Sonographic evaluation of hip joint effusion in osteoarthritis with correlation to radiographic findings
Authors: Birn Jeff , Pruente Ryan , Avram Raluca , Eyler William , Mahan Meredith , van Holsbeeck Marnix 
Published: November 2013

AbstractPurposeHip joint effusion is expected in rapidly destructive osteoarthritis, a diagnosis often only made retrospectively at the end stage of the disease. This study assesses whether the presence of an effusion identified during routine ultrasound‐guided hip injection may suggest a more aggressive process such as rapidly destructive osteoarthritis.MethodsAfter the observation of 10 index cases of rapidly destructive osteoarthritis in patients who presented with a joint effusion on ultrasound, we retrospectively reviewed 94 hips from 89 patients who underwent ultrasound‐guided hip injection for pain. Preinjection longitudinal ultrasound images of the anterior capsule adjacent to the femoral neck and inferior to the femoral head were reviewed to determine if a joint effusion was present and the size of the effusion if one was there. Comparison of effusion size was then made between those hips that had a clinical and radiographic diagnosis of osteoarthritis and those who had rapidly destructive osteoarthritis by comparing the severity of joint effusion, if one was present.ResultsPatients with rapidly destructive osteoarthritis were more likely to have a large joint effusion 60% (3/5) than were those with osteoarthritis 6.7% (6/89) (p = 0.013).ConclusionsLarge joint effusions identified sonographically correlate well with radiographic findings of rapidly destructive osteoarthritis. Given rapid onset and severity of the disease, when a large joint effusion is identified on routine hip intervention, patients should be forewarned of the potential for this disease process. © 2013 Wiley Periodicals, Inc. J Clin Ultrasound 42:205–211, 2014
Congenital fibrosarcoma of the bowel: Sonographic description of a rare case of neonatal intestinal obstruction
Authors: Bruno Costanza , Caliari Giuliana , Zampieri Nicola , Segala Diego , Pozzi‐Mucelli Roberto 
Published: November 2013

ABSTRACTA case of localization in the bowel of congenital fibrosarcoma (a rare soft‐tissue tumor usually occurring in the extremities) causing intestinal obstruction in a newborn girl is described. A focal thickening of the ileal wall with features mimicking intussusception was identified at sonography; the final diagnosis was achieved by means of molecular analysis after surgical removal of the mass. © 2013 Wiley Periodicals, Inc. J Clin Ultrasound 42:363–366, 2014
Revisits and postoperative hemorrhage after adult tonsillectomy
Authors: Bhattacharyya Neil , Kepnes Lynn J. 
Published: November 2013

Objectives/HypothesisDetermine revisits and reasons for revisits after adult tonsillectomy.Study DesignCross‐sectional analysis of multistate ambulatory surgery and hospital databases.MethodsAmbulatory adult tonsillectomies performed as the sole procedure were extracted from the State Ambulatory Surgery databases for New York, Florida, Iowa, and California for 2010. Cases were linked to the State Emergency Department databases and the State Inpatient databases for visit encounters occurring 0 to 14 days after tonsillectomy. The number of revisits (including readmissions) was determined as well as the reason for revisit categorized as post‐tonsillectomy bleeding, acute pain, or fever/dehydration. The overall rate of occurrence of and intervention rate for post‐tonsillectomy bleeding was determined.ResultsA total of 7,748 adult tonsillectomies were examined (mean age, 29.2 years; 64.4% female). Overall, 11.6% of patients had a revisit after tonsillectomy (9.6% revisited the ambulatory surgery center, 78.8% the emergency department, and 11.6% to inpatient admission). The primary diagnoses at the first revisit were bleeding (41.3%), acute pain (22.1%), and fever/dehydration (13.2%). Overall, 2.1% of patients incurred a second revisit after adult tonsillectomy (10.7% of these to inpatient admission). Among all tonsillectomies, 4.8% of adult tonsillectomies presented with a bleeding diagnosis at a first revisit. Overall, 2.2% underwent a procedure to control bleeding at a first revisit.ConclusionsThe current data quantify at a multistate level revisits, revisit diagnoses, and procedural rates for post‐tonsillectomy bleeding in the adult population. Interventions to offset revisits for acute pain and fever/dehydration should be explored to decrease adult tonsillectomy morbidity.Level of Evidence2b. Laryngoscope, 124:1554–1556, 2014