bluuebunny/crossref_metadata_2025_split huggingface dataset:
The smell of infection: Disease surveillance in insects using volatile organic compounds
Authors: Asiri Ayman , Perkins Sarah E. , Müller Carsten T. 
Published: August 2024

Abstract
Insects play crucial roles in nearly every ecosystem and provide a wide array of ecosystem services. However, both managed and wild insect populations face threats from parasites and pathogens, which require surveillance to mitigate.
Current infectious disease surveillance methods for insects often involve invasive, time‐consuming and occasionally destructive techniques, such as manual inspections and molecular detection.
Volatile organic compound (VOC) surveillance provides a real‐time, accurate and non‐invasive alternative for disease detection and has been well‐established in humans and livestock.
Recent advances in sensor technology now allow for the development of in‐field VOC surveillance devices. This review explores the need for disease surveillance in insects and highlights recent advances of using VOCs for this purpose, focusing on honey bees as an example.
We outline potential applications, challenges and future prospects of using VOCs for insect disease surveillance, providing examples of how this technology could be globally applied to mitigate the impacts of disease in a range of insect systems.
Do Audit Efforts Reduce Stock Price Crash Risk? The Role of Corporate Governance
Authors: Lee Sang Hyuk , Jung Nam Chul 
Published: August 2024

AbstractThis study investigates the Korean audit market, revealing that increased audit efforts correlate with reduced stock price crash risk, suggesting audits bridge the information gap between managers and investors, deterring negative news hoarding. The study also finds that this relationship is stronger in firms with more external directors, institutional investor presence, and financial analyst oversight, highlighting the importance of robust corporate governance. The research implies that in emerging markets, comprehensive audits and strong governance are crucial to protect investors from the adverse effects of stock price crashes.
Intra‐ and Inter‐Rater Reliability of Linear and Nonlinear Measures of Short‐Term Heart Rate Variability Following Combat‐Related Traumatic Injury
Authors: Maqsood Rabeea , Schofield Susie , Bennett Alexander N. , Khattab Ahmed , Bull Anthony M. J. , Fear Nicola T. , Boos Christopher J. ,   for the ADVANCE Study
Published: August 2024

ABSTRACTBackgroundHeart rate variability (HRV) is a marker of autonomic function. However, the reliability of short‐term HRV measurement in individuals with combat‐related traumatic injury (CRTI) remains undetermined.MethodsAn intra‐ and inter‐rater reliability study was conducted using a subsample (n = 35) of British servicemen with CRTI enrolled in the ongoing ADVANCE study. A five‐minute epoch of single‐lead electrocardiogram data collected during spontaneous breathing was used to measure HRV. HRV analyses were independently performed by two examiners using Kubios. Intraclass correlation coefficient (ICC), standard error of measurement (SEM), minimum detectable change (MDC), and coefficient of variance were calculated for linear [root mean square of successive difference (RMSSD), standard deviation of NN interval, low‐frequency, high‐frequency, total power] and nonlinear (SD1‐2, acceleration and deceleration capacities, sample entropy) measures. Bland–Altman %plots were used to assess bias in intra‐ and inter‐rater HRV data.ResultsThe mean age of participants was 39.3 ± 6.3 years. An excellent ICC score of 0.9998 (95% CI 0.9997, 0.9999) was observed for intra‐rater analyses of RMSSD, and similar excellent ICC scores were seen for all other HRV measures. The inter‐rater reliability analyses produced an excellent ICC score (range 0.97–1.00). Comparatively, frequency‐domain measures produced higher MDC% and SEM% scores than time‐domain and nonlinear measures in both inter‐ and intra‐rater analyses. The Bland–Altman plots revealed relatively higher bias for frequency‐domain and nonlinear measures than time‐domain measures.ConclusionECG‐related short‐term HRV measures were reliable in injured servicemen under spontaneous breathing. However, the reliability appeared better with the time‐domain measure than frequency‐domain and nonlinear measures in this sample.
Facial growth dynamics dictate optimal facemask fitting during the first year of life
Authors: Haase Bianca , Badinska Ana‐Maria , Sowula Julian , Springer Laila , Schwarz Christoph E. , Stauch Anette , Weismann Christina , Poets Christian F. , Wiechers Cornelia 
Published: August 2024

AbstractAimThe aim of this study is to prevent mask leak during ventilation in infant emergencies, appropriate facemask fitting is essential. Therefore, we investigated facial profiles during the first year of life and their correlation with the correct sizing of masks.MethodsThis is a post hoc subgroup analysis of 32 healthy term infants, based on a prospective observational study performed from September 2018 to December 2019 in Tuebingen, Germany. In 3‐monthly intervals, facial aspects were measured based on anatomical landmarks in three‐dimensional frontal photographs to describe their changes across the first year of life. All infants were awake and breathing spontaneously; none required any anaesthesia.ResultsIn 130 3D images, mean distance between nasion and gnathion was 54 mm (3.3) measured at birth and 70 mm (3.5) at age 12 months. Gompertz models showed relevant growth‐related changes in the facial profile in vertical but not horizontal direction. Vertical growth occurred mainly in the first 6 months. Boys and girls differed by an average of about 2 mm (boys >girls).ConclusionBased on our findings, it should now be verified whether the 50 mm facemasks are suitable for infants from birth to 2 months of age, respectively, the 60 mm version for infants aged three to 12 months.
Non‐invasive analysis of Chinese traditional dyes in royal textiles of the Qing dynasty by excitation–emission matrix fluorescence
Authors: Zhao Li , Wang Yunli , Zhang Yun , Wang Xu , Lei Yong , Gu An 
Published: August 2024

AbstractChinese royal textiles of the Qing dynasty are widely collected around the world, creating a significant demand for dye identification in these textiles. However, the need for sampling in conventional analytical methods greatly limits their applicability. To address this issue, a non‐invasive analysis method based on excitation–emission matrix (EEM) fluorescence was developed. In this study, the EEM spectra of 18 typical natural dyeing recipes used for royal textiles of the Qing dynasty were systematically characterized. The results demonstrated that EEM fluorescence is effective in discriminating between natural dyes with similar colour hues and various dyeing techniques. Furthermore, the dyeing recipes of two historical kesi cushions in the Palace Museum, Beijing, were non‐invasively decoded.
Plasma ofCS‐modified CD44 predicts the survival of patients with lung cancer
Authors: Wu Zi‐Yi , Yang Da‐Wei , He Yong‐Qiao , Wang Tong‐Min , Zhou Ting , Li Xi‐Zhao , Zhang Pei‐Fen , Xue Wen‐Qiong , Zhang Jiang‐Bo , Mu Jianbing , Jia Wei‐Hua 
Published: August 2024

AbstractPlasma levels of oncofetal chondroitin sulfate (ofCS)‐modified CD44 have emerged as a promising biomarker for multi‐cancer detection. Here, we explored its potential to predict the survival of patients with lung cancer. A prospective observational cohort was conducted involving 274 newly diagnosed patients with lung cancer at the Sun Yat‐sen University Cancer Center from 2013 to 2015. The plasma levels of ofCS‐modified CD44 were measured, and Cox regression analysis was performed to assess the association between plasma‐modified CD44 levels and overall survival (OS) as well as other prognostic outcomes. Prognostic nomograms were constructed based on plasma ofCS‐modified CD44 levels to predict survival outcomes for patients with lung cancer. Patients with high expression ofCS‐modified CD44 exhibited significantly worse outcomes in terms of OS (HR = 1.61, 95%CI = 1.13–2.29, p = 0.009) and progression‐free survival (PFS). These findings were consistent across various analyses. The concordance index of the prognostic nomogram for predicting OS in both the training set and validation set were 0.723 and 0.737, respectively. Additionally, time‐dependent receiver operating characteristic (ROC) curves showed that the nomogram could serve as a useful tool for predicting OS in patients with lung cancer. Plasma ofCS‐modified CD44 may serve as an independent prognosis marker for patients with lung cancer. Further validation of its predictive value could enhance prognostic assessment and guide personalized treatment strategies for patients with lung cancer.
A genomic framework to assist conservation breeding and translocation success: A case study of a critically endangered turtle
Authors: Nelson Holly V. , Farquharson Katherine A. , Georges Arthur , McLennan Elspeth A. , DeGabriel Jane L. , Giese Melissa , Ormond Christopher , McFadden Michael , Skidmore Adam , Prangell Jarrad , Belov Katherine , Hogg Carolyn J. 
Published: August 2024

AbstractConservation breeding programs are an effective approach to addressing biodiversity loss. Captive populations are managed to maintain genetic diversity, yet there remains an “implementation gap” in effectively translating molecular genetic data into management. Technological advancements are facilitating rapid generation of genetic data, increasing accessibility for breeding programs. In 2010, Frankham and colleagues proposed a six‐stage process for establishing successful conservation breeding and release programs. Here, we describe the conservation breeding program for the critically endangered Bellinger River turtle (Myuchelys georgesi) and characterize the value of genetic sampling for informing management actions. By generating a chromosome‐level genome and population genetic data, we investigated past and present diversity and assessed relatedness among captive founders. We present a framework modeled on Frankham and colleagues six stages to assist managers in implementing genetic data into actionable conservation strategies. This framework, and worked case study, for managers aims to better guide implementation of genetic approaches into conservation breeding programs.
Marshaling science to advance large landscape conservation
Authors: Daskin Joshua H. , Meeks Angeline , Sclater Vivienne L. , Sorfleet Julie M. , Oetting Jon , Hoctor Thomas S. , Guthrie Joseph M. , Swain Hilary M. 
Published: August 2024

AbstractApplying science to conservation requires deliberate planning and action infrequently taught in academic settings. To illustrate impactful analysis and science communication, we describe scientific activities targeting the needs of land trusts, NGOs, landowners, and government agencies working to conserve the Florida Wildlife Corridor (“Corridor”). This 7.2 million hectare area is prioritized for habitat connectivity conservation in the US state of Florida. Our activities are built on decades of science guiding Florida land conservation. We quantified threats (e.g., average of over 14,000 ha of development/year from 2001 to 2019) and socio‐ecological benefits of Corridor conservation, prioritized yet‐to‐be‐conserved Corridor areas, produced and shared a new statewide connectivity model, and convened groups to identify campaign science needs. The new connectivity model—the Florida Circuit Model—supported the geography of the Corridor, as designated, and facilitates local (10 km radius, or less) conservation planning. Our efforts have contributed to allocation of over $2 billion for land conservation and the permanent protection of over 82,000 ha within the Corridor by state agencies from June 2021 to March 2024. Targeting science to outreach and policy, planning, and management decisions can motivate public, media, researcher, and government support for land conservation, improve conservation interventions, and attract research funding.
Assessing the societal value of health lost to alcohol use in India compared to excise taxes on alcohol sales
Authors: Zadey Siddhesh 
Published: August 2024

AbstractIntroductionWe retrospectively studied the societal value of lost health due to alcohol use and compared it with excise taxes on alcohol sales for India in 2019.MethodsWe estimated the overall alcohol‐attributable disease burden using disability‐adjusted life‐years (DALY) for India and its 30 states for all causes with alcohol use as a risk factor from the GBD 2019 Study. The societal value of lost health was calculated using value of life‐year (VLY) approach by multiplying region‐specific factors from ‘Global Health 2035’, 2019–2020 GDP per capita and DALYs. We acquired the national and state‐level (top 10 states) alcohol sales excise taxes from the Reserve Bank of India. Net losses were assessed by subtracting the revenue collected from excise taxes from VLY. All values are in Indian rupees (INR).ResultsThe societal value of health lost due to alcohol use in India was 6.2 (95% uncertainty interval 4.8, 7.8) trillion INR in 2019. The absolute state‐level values varied from 7.3 (4.7, 10.4) billion INR in Mizoram to 1.1 (0.8, 1.4) trillion INR in Maharashtra. The per capita values ranged from 950.2 (642.9, 1285.3) INR for Bihar to 61,332 (39,273.7, 87,288.5) INR for Mizoram. Nationally, excise tax collection from alcohol sales was 1.8 trillion INR depicting a net loss of 4.4 (3.1, 6.0) trillion. Maharashtra had the largest absolute and per capita net loss.Discussion and ConclusionsThese are novel estimates depicting the net losses due to alcohol use in India with direct policy implications to disincentivise sales and adequately raise taxes.
[P3]PP, a stable, long‐acting pancreatic polypeptide analogue, evokes weight lowering and pancreatic beta‐cell‐protective effects in obesity‐associated diabetes
Authors: Tanday Neil , Zhu Wuyun , Tarasov Andrei I. , Flatt Peter R. , Irwin Nigel 
Published: August 2024

AbstractAimTo thoroughly investigate the impact of sustained neuropeptide Y4 receptor (NPY4R) activation in obesity‐associated diabetes.MethodsInitially, the prolonged pharmacodynamic profile of the enzymatically stable pancreatic polypeptide (PP) analogue, [P3]PP, was confirmed in normal mice up to 24 h after injection. Subsequent to this, [P3]PP was administered twice daily (25 nmol/kg) for 28 days to high‐fat‐fed mice with streptozotocin‐induced insulin deficiency, known as HFF/STZ mice.ResultsTreatment with [P3]PP for 28 days reduced energy intake and was associated with notable weight loss. In addition, circulating glucose was returned to values of approximately 8 mmol/L in [P3]PP‐treated mice, with significantly increased plasma insulin and decreased glucagon concentrations. Glucose tolerance and glucose‐stimulated insulin secretion were improved in [P3]PP‐treated HFF/STZ mice, with no obvious effect on peripheral insulin sensitivity. Benefits on insulin secretion were associated with elevated pancreatic insulin content as well as islet and beta‐cell areas. Positive effects on islet architecture were linked to increased beta‐cell proliferation and decreased apoptosis. Treatment intervention also decreased islet alpha‐cell area, but pancreatic glucagon content remained unaffected. In addition, [P3]PP‐treated HFF/STZ mice presented with reduced plasma alanine transaminase and aspartate transaminase levels, with no change in circulating amylase concentrations. In terms of plasma lipid profile, triglyceride and cholesterol levels were significantly decreased by [P3]PP treatment, when compared to saline controls.ConclusionCollectively, these data highlight for the first time the potential of enzymatically stable PP analogues for the treatment of obesity and related diabetes.
Reduced insulin clearance in paediatric metabolic (dysfunction)‐associated fatty liver disease and its dual role in beta‐cell offload and diabetes risk
Authors: Jiang Li , Lai Jinxin , Xu Xu , Lu Yang , Gu Kefeng , Chen Sha , Xu Lulian , Liu Kerong 
Published: August 2024

AbstractAimDiminished hepatic insulin clearance (HIC) is observed in obese adults and is presumed to be mediated by fatty liver. However, few reports have examined HIC in Chinese children with metabolic (dysfunction)‐associated fatty liver disease (MAFLD). This study aimed to investigate the correlation between HIC, insulin sensitivity and β‐cell function in obese Chinese children with MAFLD.MethodsIn total, 204 obese children (74 MAFLD) aged 4–17 years were enrolled into this study. HIC, insulin sensitivity and β‐cell function were calculated using the oral glucose tolerance test (1.75 g/kg body weight). Correlation analyses between the HIC and clinical variables were performed using Pearson's product–moment correlation coefficients. HIC and glucose homeostasis were assessed in a high‐fat diet mouse model, and liver samples were collected for molecular analysis.ResultsObese children with MAFLD exhibited significantly lower HIC (AUCC‐peptide/insulin ratio, p = 0.0019), higher insulin resistance (homeostatic model assessment of insulin resistance, p = 0.002), and increased compensatory β‐cell function (homeostatic model assessment‐β, p = 0.046) than obese children without liver involvement. Notably, HIC was negatively correlated with insulin sensitivity (r = −0.5035, p < 0.0001) and β‐cell function (r = −0.4576, p < 0.0001). However, pancreatic β‐cell dysfunction (p = 0.046) was accompanied by future reduced HIC (p = 0.034) in children with MAFLD in prediabetes. In a high‐fat diet mouse model, MAFLD mice showed a 50% reduction in insulin‐degrading enzyme expression, consistent with the observed decrease in HIC.ConclusionsA lower HIC may offload pancreatic β‐cells at an early stage. However, obese children with MAFLD are at risk of developing diabetes, and preventive efforts should be prioritized.
Effects of Physical Activity on Disordered Eating Behaviours in Individuals With a Psychotic Disorder
Authors: Carrier Kathya , Abdel‐Baki Amal , Thériault Lorilou , Karelis Antony D. , Lecomte Tania , Romain Ahmed Jérôme 
Published: August 2024

ABSTRACTAimThis study aims to determine the effect of physical activity on cognitive restraint, uncontrolled eating and emotional eating in individuals with a psychotic disorder.MethodsTwenty‐seven participants with a psychotic disorder (55% male; mean age: 30 ± 7.5 years; Caucasian: 66.7%; schizophrenia spectrum disorders: 44.4%; bipolar disorder with psychotic features: 29.6%) took part in a 6‐month bi‐weekly physical activity program (walking, running, yoga, cycling and dancing). The Three‐Factor Eating Questionnaire was used to assess participant's eating behaviours, and the frequency of completed physical activity sessions was compiled.ResultsThe mixed models analysis approach revealed that the level of cognitive restraint remained unchanged (pre: 39.2 ± 18.7 vs. post: 44.1 ± 18.3; p = 0.24), while the levels of uncontrolled eating (pre: 39.7 ± 19 vs. post: 31.6 ± 19.7; p = 0.02) and emotional eating (pre: 45.5 ± 22.3 vs. post: 32.2 ± 22.2; p < 0.001) decreased at the end of the 6‐month physical activity program.DiscussionThis study showed that physical activity has positive effects on disordered eating behaviours in individuals with a psychotic disorder, similarly to previous studies on other populations (e.g., overweight and obese participants, postmenopausal women).ConclusionFurther studies are warranted to better understand the role of physical activity in moderating eating behaviours.
MYC translocation is a valuable marker for the development and relapse of extramedullary disease in multiple myeloma
Authors: Song Yuhang , Du Jianhua , Jin Xianghong , Li Hui , Jia Congwei , Liu Yuanyuan , Li Kaimi , Zhou Daobin , Zhuang Junling 
Published: August 2024

AbstractObjectiveTo study the cytogenetic characteristics of extramedullary disease (EMD) in patients with multiple myeloma (MM) and their impact on prognosis.MethodsPatients with newly diagnosed MM (NDMM) at Peking Union Medical College Hospital (Beijing, China) between June 2007 and December 2019 were recruited for this study. Demographic information, clinical data, fluorescence in situ hybridization (FISH) results of marrow and tissue samples, and survival outcome data were collected.ResultsA total of 439 patients with NDMM were divided into those without EMD (non‐EMD, n = 339), those with EMD with primary paraosseous plasmacytoma (pEMD‐B, n = 48), those with primary EMD with soft‐tissue involvement (pEMD‐S, n = 33), and those with secondary EMD (sEMD, n = 19). The incidence of EMD was 18.5% (81/439) at diagnosis and 22.8% (100/439) throughout the disease course. Comparison of FISH results showed a higher proportion of RB1 deletion (n = 20; 60.0% vs. 20.0%, p = .013) and MYC translocation (n = 12; 44.4% vs. 12.5%, p = .041) in the extramedullary tissues than in the paired bone marrow samples. At diagnosis, the percentage of MYC translocations in the sEMD group was notably higher than that in the non‐EMD group (55.6% vs. 15.5%, p = .012). The median overall survival (OS) of patients with pEMD‐S (32 months) and sEMD (17 months) was significantly shorter (both p = .001) than that of non‐EMD patients (60 months).ConclusionSoft‐tissue EMD can be considered a high‐risk condition, even in the era of novel agents. MYC translocation can serve as a valuable marker that correlates with extramedullary spread and relapse in patients with MM and should be considered for inclusion in routine FISH panels in clinical practice.
Joint Declaration on the Doctrine of Justification
Authors: O'Brien Christopher M. 
Published: August 2024

AbstractThe year 2024 marks 25 years since the Lutheran World Federation and the Catholic Church signed the Joint Declaration on the Doctrine of Justification (JDDJ), along with an Official Common Statement and an attached Annex, on 31 October 1999. In reflecting upon the JDDJ, this article attempts to evaluate the impact of the declaration by addressing the following questions: What did the JDDJ accomplish, and what did it fail to achieve? What progress has been made since 1999 to build on the work of the JDDJ? What work still needs to be done moving forward in Catholic–Lutheran dialogue? The article concludes that the JDDJ has had a ground‐breaking impact in ecumenical dialogue – both in and beyond the Catholic–Lutheran context – that continues to unfold today. While there is a long way to go in the ecumenical venture, the JDDJ represents a pivotal moment and a sign of hope for visible Christian unity, which is the goal of ecumenism.
Unlocking the potential: A review of artificial intelligence applications in wind energy
Authors: Dörterler Safa , Arslan Seyfullah , Özdemir Durmuş 
Published: August 2024

AbstractThis paper presents a comprehensive review of the most recent papers and research trends in the fields of wind energy and artificial intelligence. Our study aims to guide future research by identifying the potential application and research areas of artificial intelligence and machine learning techniques in the wind energy sector and the knowledge gaps in this field. Artificial intelligence techniques offer significant benefits and advantages in many sub‐areas, such as increasing the efficiency of wind energy facilities, estimating energy production, optimizing operation and maintenance, providing security and control, data analysis, and management. Our research focuses on studies indexed in the Web of Science library on wind energy between 2000 and 2023 using sub‐branches of artificial intelligence techniques such as artificial neural networks, other machine learning methods, data mining, fuzzy logic, meta‐heuristics, and statistical methods. In this way, current methods and techniques in the literature are examined to produce more efficient, sustainable, and reliable wind energy, and the findings are discussed for future studies. This comprehensive evaluation is designed to be helpful to academics and specialists interested in acquiring a current and broad perspective on the types of uses of artificial intelligence in wind energy and seeking what research subjects are needed in this field.