bluuebunny/crossref_metadata_2025_split huggingface dataset:
1836 – Functional Remission In Depression And Patient Satisfaction Index: Results Of The Diapason Study
Authors: Mouchabac S. , Lemoine P. , Baylé F.J. 
Published: July 2013

IntroductionA consensus is emerging for functional remission to be routinely assessed in the treatment of major depression. This is because, in many cases, clinical remission is not necessarily accompanied by optimum functioning which would favour the rehabilitation of patients.AimThe objective was to study in depressed patients treated with agomelatine their global clinical response and their social functioning. The QFS (Questionnaire de Fonctionnement Social) provides information on specific areas of functioning: objectively via the frequency of social behaviours (F: Frequency index) and subjectively via the patient's perception of his/her social performance (S: Satisfaction index), making up a global index (G).Method3139 patients were followed over 6-8 weeks. Assessments were carried out at inclusion (C1) and at the follow-up visit (C2): QIDS-C, CGI, QFS and SDS.ResultsAt C1 the mean QIDS-C score was 17.0 ± 3.4. For the QFS-G: 72.4% of functioning was “poor”. The SDS global score was 21.3 ± 4.8. At C2, a reduction in the QIDS score was observed: -7.9 ± 4.7 (p < 0.01). QIDS response rates were 50.2% [48.4-52.0%]. Improvement on the SDS was significant and the 3 QFS indexes saw significant increases, but more markedly so for S (6.7 ± 6.7) than for F (4.2 ± 5.4).ConclusionThe results show an improvement in the social functioning of depressed patients treated with agomelatine. They suggest that a specific action of the treatment contributes to providing the patient with the possibility of better rehabilitation into his/her social, family and professional environments.
1837 – Characteristics Of Social Networks Of Patients With Psychotic Disorders: a Systematic Literature Review
Authors: Palumbo C. , Matanov A. , Volpe U. , Priebe S. 
Published: July 2013

IntroductionThe concept of the “social network” (SN) describes the set of social relationships of an individual. SNs of patients with psychotic disorders have often been investigated in the last few decades, however, diverse theories and different assessment methods were utilised within this field of research.ObjectivesTo assess morphological (size, density, degree) and interactional (direction and intensity) characteristics of SNs of patients with psychotic disorders reported in different studies.AimsTo explore the characteristics of the SNs of psychotic patients and to identify the factors that influence their size and composition.MethodsA systematic literature review was carried out using the databases MEDLINE, PsychInfo and EMBASE. When feasible, the characteristics of SNs were compared across studies.ResultsOut of 739 identified studies, 142 reported quantitative findings on SN characteristics. 27 (19%) of them reported figures on the size of SNs in a way that allowed meaningful comparison across studies. For all other SN characteristics, only descriptive accounts were possible. The overall mean network size was 15.2 (SD 9.4). Being single was negatively correlated with SN size.ConclusionsThe concept of SNs in psychotic disorders has been underpinned by diverse theoretical frameworks and assessed with a variety of tools. Only a small number of studies were methodologically comparable, which makes findings on SN characteristics and associated factors difficult to interpret. There is a need to develop standardised instruments in order to advance the quality of the research in the field.
1838 – Preliminary Results Of Using The Geriatric Depression Scale In Serbian Elderly Population
Authors: Ignjatovic Ristic D. , Jovic J. , Bukumiric Z. , Knezevic M. 
Published: July 2013

IntroductionLate life depression is still not well recognized. As depression increased risk for mortality and morbidity in elderly,it is necessary to have efficient instrument for detecting and measuring depression in this population. The Geriatric Depression Scale (GDS-15) is a screening test for depression in late life but it is not use in Serbian erderly population.ObjectivesTo show preliminary results of using the Short Form Geriatric Depression Scale (GDS-15) in Serbian elderly population.AimsWe wanted to estimate whether this scale correlate with Beck Depression Inventory (BDI) which has been validated in Serbia.MethodsWe studied 248 pariticipants (40,3% were male,59,7% female) age 65 and older. Mean age for the whole sample was 70,87 ± 5,79. Hamilton depression scale, BDI and GDS-15 we used for assessing depressive symptomathology and two psychiatrist confirmed diagnosis of depression. According to inclusion criteria,102 participants met criteria for depression (experimental group) and 146 were in control group.ResultsWe found statistically significant difference in mean GDS-15 score between experimental (4,83 ± 4,93) and control group (1,51 ± 1,42) and no gender differences were found according to GDS-15 mean score. Significant difference (p≤ 0,05) was found on GDS item 11(Do you think it is wonderful to be alive now?),where woman scored higher in control group. Strong positive correlation was found between BDI and GDS-15 mean scores (r=0,863; p< 0,001).ConclusionsThe preliminary results confirm that GDS may be accepted as useful tool for measurement depression in Serbian elderly population. This may facilitate recognition and treatment of depression in elderly.
1839 – The Influence Of Psychoactive Substances On Paranoid Schizophrenia
Authors: Verbenko V.A. , Stroevskiy V.V. 
Published: July 2013

ObjectivesDuring the last years an increasing number of abusers of various psychoactive substances (surfactants), leads to a high incidence depending on the surfactant in patients with various forms of mental disorders, including schizophrenia patients. Interaction between schizophrenia and drug addiction is very complex, because of atypical clinical picture of both diseases and there are a lot of different opinions about the impact of drug use on the progression of schizophrenia. That's why this problem must be studied.The main aim of researchTo study influence of psychoactive substances (alcohol, cannabis) on the paranoid schizophrenia's clinic, to develop treatment and prevention measures. This research includes studies of 60 patients with paranoid schizophrenia and addiction of cannabis and alcohol.ResultsAdmission mentally active agents in patients with schizophrenia impact on the overall clinical and dynamic patterns of endogenous disease: manifest in patients receiving mentally active substances episode schizophrenia are exogenous type. With the progression of the development of schizophrenia complicated by psychoactive substances we can see smoothing of psychotic defect. Adherence of psychoactive substances to schizophrenia affect social functioning.ConclusionsThe significant differences in the dynamics of mental health status in patients with paranoid schizophrenia, depending on psychoactive substances addiction were described. Joining alcohol and cannabis addiction increases the frequency of hospitalizations, but did not affect the level of social functioning of patients with schizophrenia.
1843 – Depression In The Peripartum Period In Association With Salivary Cortisol Levels
Authors: Iliadis S.I. , Hellgren C. , Sylvén S. , Papadopoulos F. , Sundström Poromaa I. , Skalkidou A. 
Published: July 2013

IntroductionThe Hypothalamic-Pituitary-Adrenal Axis (HPA axis) has been implicated in the pathogenesis of many affective disorders. Peripartum depression is a condition that includes depressive episodes occurring during pregnancy and the postpartum period. During uncomplicated pregnancy, mean cortisol levels rise substantially, mostly due to high levels of corticotropin releasing hormone produced by the placenta (p-CRH). The latter also suppresses hypothalamic CRH, leading to hypo-cortisolemia after partus. Cortisol concentration is usually normalised within two weeks after delivery. Failure of the above process results in continuing hypo-cortisolemia, which might increase susceptibility to PPD.Objectives/aimsThe current study aims to investigate the relationship between evening salivary cortisol levels and depression during the peripartum period.MethodsThree hundred and forty six pregnant women were asked to participate in the study. They completed the Edinburgh Postnatal Depression Scale (EPDS) and the Spielberger State-Trait Anxiety Inventory-State version (STAI-S) at the 36th week of pregnancy and the 6th week after delivery. At both times, study subjects were also asked to collect evening salivary samples by using a mail-delivered kit. Moreover, they were interviewed at the 36th week of pregnancy using the Mini International Neuropsychiatric Interview (MINI).ResultsPreliminary results indicate significantly higher evening salivary cortisol levels in depressed women during late pregnancy compared to healthy controls. No difference in cortisol levels was found between women with postpartum depression and healthy controls.ConclusionsOur study results support the hypothesis that depression during pregnancy resembles melancholic depression characterized by hyperactivity of the HPA-axis and hyper-cortisolemia.
1851 – Prevalence Of Mental Disorders Among Karajá Indians In a Primary Psychiatry Service
Authors: Caixeta L.F. , Taveira D.L.R. , Vargas C.M. 
Published: July 2013

IntroductionMental disorders are highly prevalent in the general population and are among the factors that most affect the quality of life, creating great social impact. The national literature that discusses mental disorders in indigenous is very scarce.ObjectivesTo characterize the socio-demographic profile and major psychiatric disorders that affect a sample of indigenous villagers who sought primary care mental health.MethodsWe developed a retrospective cross-sectional study of a consecutive series of cases of Karajá Indians who sought primary care. Symptoms were classified as major syndromes: affective, anxiety, psychotic and organic, and then calculated the prevalence of each syndrome and psychiatric diagnosis according to DSM-IV, as well as their association with sociodemographic variables.Results63% of the sample were male. Aged 10-67 years, mean 30.7 years. Schooling to 1st elementary school was 46.2%, and 26.9% illiteracy. 54.5% are married. The affective syndrome was present in 50% of patients, depression in 28%, and 21% in Bipolar Disorder. The anxiety disorder accounted for 8%, the psychotic 15%, and 12% organic. Considering the whole sample, 20% are composed of married patients with affective syndrome. Of the patients diagnosed with affective syndrome, 30% had problems with alcohol and drugs, 38% had suicidal ideation, and suicide attempt 6%. Regarding treatment used, 35% and 33% of patients were on antidepressants and mood stabilizers, respectively.ConclusionThere is a high prevalence of Depression and Bipolar Disorder among the causes of mental disorder among Indians who seek primary care.
1852 – Psychosis In Parkinson's Disease. a Case Report
Authors: Diaz Marrero G. , Suarez Benitez M.N. , Vera-Barrios E. , Hernandez-Dorta A. , Gonzalez I. , Quant-Herrera P. , Barrau Alonso V.M. , Yelmo S. 
Published: July 2013

IntroductionParkinson's disease (PD) is classified primarily as a movement disorder. Psychiatric complications, however, are common during the progression of the disease. Psychosis is rare in untreated patients with PD, but the prevalence rises to 40% during dopaminergic treatment.ObjectivesWe report the clinical course of a ropinirole induced psychosis in a 57-year-old female with PD.Aims/methodsThe patient was treated with different antiparkinsonians (rasagiline, ropinirole and levodopa), and after a dosage increase of ropinirole, psychotic symptoms appeared (auditory hallucinations and paranoid delusion). Antipsychotic treatment started with quetiapine and a gradual dose reduction of antiparkisonians. Nevertheless, psychotic symptoms required a hospital admission.Rasagiline was suspended at admission, the dose of ropinirole was decreased until withdrawal, and the dose of levodopa was reduced. The dose of quetiapine was increased to control psychotic symptoms.ResultsThe pathogenesis of psychosis in PD is poorly understood. It has been related with the presence of dementia and concomitant treatment with dopaminergic agonists (DA). According to the literature, pergolide is associated with a significantly increased risk for the development of psychosis, followed by ropinirole, pramipexole and cabergoline, whereas levodopa has the lowest associated risk. Treatment includes, in the first place, suspending anticholinergics and selegiline, and then, amantadine, DA, and entacapone. Finally, levodopa may also be reduced. These patients frequently require antipsychotic treatment that may worsen extrapyramidal symptoms.ConclusionsPsychosis should be considered in PD, especially in patients treated with DA. Treatment begins with reducing antiparkinsonians and then adding antipsychotics. Clozapine and quetiapine are a good choice.
1861 – Affective Temperaments And Somatization In a 55 Healthy Subjects Sample
Authors: Gentile A. , Ventriglio A. , Bonfitto I. , Bellomo A. 
Published: July 2013

IntroductionSome authors have found an association between affective temperaments and mood fluctuations, and a common comorbidity between somatization disorders and mood disorders. In addition, It’s known a significant association between abnormal affective temperaments and somatoform disorders.ObjectivesThe present study investigated associations between affective temperaments and somatization in a 55 healthy subjects sample.AimThe aim of the study was to describe associations between affective temperament and somatization scores in a sample of healthy subjects.MethodIn this observational study we adopted the following rating scales: Mini International Neuropsychiatric Interview (MINI), 17-item Self Rating Depression Scale (SDS), Hypomania check list 32(HCL-32), Self Rating Anxiety Scale (SAS), DCPR diagnostic criteria for psychosomatic research, Brief TEMPS-A, Modified Somatic Perception Questionnaire (MSPQ), Somatosensory Amplification Scale- SSAS.ResultsLogistic regression analysis showed that cyclothymic temperament scores at Brief TEMPS-A are associated with MSPQ scores for somatic perception (somatosensory amplification) and SASS scores (hypochondriacal aspects). Moreover, depressive temperaments scores at Brief TEMPS-A are significantly associated to MSPQ tools.ConclusionOur data suggest an association between an affective temperamental dysregulation and somatization aspects in a 55 healthy subjects sample.
1865 – Cognitive Adaptation Training For Long-term Hospitalized Patients With Schizophrenia Living In The Netherlands
Authors: Quee P.J. , Stiekema A. , Schneider H. , Wiersma D. , Velligan D.I. , Bruggeman R. 
Published: July 2013

IntroductionCognitive impairment substantially contributes to functional disability in schizophrenia. Methods to improve functioning in long-term hospitalized patients are lacking. Cognitive Adaptation Training (CAT) improves functional outcomes in schizophrenia outpatients living in the US.Objectives/aimsTo investigate the efficacy of CAT in long-term hospitalized schizophrenia patients living in the Netherlands.MethodsTwenty schizophrenia inpatients participated in this study. Ten patients received treatment as usual (TAU), the other 10 patients received TAU plus CAT. CAT uses environmental supports (e.g. calendars, alarm clocks) in order to compensate the impact of cognitive impairment. CAT was provided for 8 months. Assessments of the Multnomah Community Ability Scale (MCAS) and SOFAS were conducted at baseline, halfway, and after 8 months. In addition, participation in work-related activities (e.g. woodworking, graphic center) was recorded every month for a duration of 12 months. Anayses of mixed models were conducted, using the baseline score as a covariate.ResultsAfter 6 months, CAT patients spent significantly more partial days at activity centers, compared to TAU patients. Differences remained significant after 12 months. With regard to the other measures, CAT patients showed improvement on the SOFAS and the MCAS after 8 months (trend) with a large effect size (0.8).ConclusionsThese findings suggest that inpatients with schizophrenia may benefit from CAT. In particular, the method may be effective to increase productivity in this chronic population. These results are promising, research with a larger sample size is needed to further investigate the effect of CAT in long-term hospitalized psychiatric patients.
1871 – The Shedler-westen Assessment Procedure (swap) As a Useful Procedure In a Multi-perspective Diagnostic Process Of Personality And Eating Disorders In Adolescent Patients
Authors: Bragoszewska J. , Misiec M. , Namyslowska I. 
Published: July 2013

Diagnosis and case conceptualization are of utmost importance for treatment planning in eating and personality disorder patients. The science-practice schism, especially noticeable in personality assessment, has been a growing concern among both researchers and clinical practitioners. The Shedler - Westen Assessment Procedure (SWAP) allows for a systematic and empirically sound quantification of clinical observations and formulation of a dimensional diagnosis of personality. It offers clinicians and researchers a common “standard vocabulary” in the field of personality assessment. Unlike self-report questionnaires, it enables clinicians to discover patient characteristics that the patients may be unlikely to disclose themselves, without subjecting patients to a pen-and-paper procedure. It offers clinicians an opportunity to rely on their perceptions and feelings, thus fostering self-awareness and a reflective stance.Preliminary results of former studies in which SWAP-200-A was used revealed three personality subgroups of adolescent anorexic patients (Zechowski, Namyslowska, Bragoszewska, Witkowska). The use of SWAP-200-A has since been incorporated by the authors into their clinical practice. The way the procedure is currently being used by the authors as part of a multi-dimensional and multi-perspective diagnostic process of personality and eating disorder patients will be presented. A case study will illustrate how the procedure may be used in assessment, treatment planning and treatment monitoring.
1872 – Comorbidity Between Panic Disorder With And Without Co-occurring Depression And Personality Disorders: a Systematic Review
Authors: Navinés R. , Gutiérrez F. , Subirà S. , Obiols J. , Binelly C. , Martín-Santos R. 
Published: July 2013

IntroductionPanic disorder is an anxiety disorder characterized by unexpected and repeated episodes of intense fear accompanied by physical symptoms. The diagnosis frequently is associated to other comorbid axis-I psychiatric disorders, especially depressive disorders. Moreover panic disorder can also be comorbid with axis-II diagnosis of Personality Disorder1(PDs).ObjectiveThe aim of this study was to evaluate the existing comorbidity between current DSM-IV axis I panic disorder with and without co-occurring depression and current DSM-IV axis II PDs.MethodsWe review all database from 1987 until January 2012 of all relevant cross-sectional and case-control studies which evaluate the comorbidity between panic disorders and PDs.ResultsWe found 97 possible papers, 20 entered in the review. Among patients with a current DSM-IV panic disorder 44.3% [34.6, 54.2] had any PDs; 6.3% [3.1, 10.4] had any cluster A-PDs; 17.9% [12.2, 24.2] any cluster B-PDs, and 34.9% [25.6, 44.7] had any cluster C-PDs. Among patients with a current DSM-IV panic disorder and co-occurring depression 61.8% [44.6, 77.7] had any personality disorder 7.2% [4.4, 10.5] had any cluster A-PDs; 24.0% [17.6, 30.9] any cluster B-PDs, and 38.6% [25.7, 52.2] had any cluster C-PDs.ConclusionsThe comorbidity between Panic disorder and Personality disorders is common. Cluster C-PDs was the most frequent PDs subtype related to panic disorder. Personality disorders were more prevalent among individuals with panic disorder and co-occurring depression. Further evaluations including dimensional and characterial dimensions are needed.Goodwin RD, Brook JS, Cohen P. Panic attacks and the risk of personality disorder. Psychol Med. 2005;35:227-35.
1879 – Interrelationship Of Prevalence Of Non-psychotic Mental Disorders, Level Of Unemployment, Poverty And Incomes On Territories Of Siberia And Far East
Authors: Gychev A. 
Published: July 2013

Analysis of 12-year dynamics of indices of documented morbidity with mental disorders on territories of Siberia and Far East and number of unemployed persons in this period has shown presence of positive close association of these data (respectively, r=0,85 and r=0,95; p<0,05). Analogous interrelationships of mental disorders has been revealed also with number of employed in economics population of able-bodied age (r=0,94 and r=0,99). We have not found significant differences in interrelationships of employed and unemployed population with indices of poverty (percent of persons with incomes below cost of living) and monetary incomes; poverty is not a distinctive characteristic of unemployment. In Siberian regions, interrelationship of poverty and number of unemployed persons and employed in economics ones is similar both in closeness and in negative directedness (r=-0,57 and r=-0,56; p<0,05). In Far East regions, correlations of considered parameters have not been identified (r=0,33 and r=0,28; p>0,2); with cash incomes, both categories of economically active population (employed and unemployed) have negative relationship at level of significance 80% (r=-0,48 и r=-0,47; p<0,2). In Siberia, considered relationships are not reliable.For non-psychotic mental disorders in Siberian region negative correlation relationship of number of patients with organic nonpsychotic disorders (r=-0,56; p<0,05), affective non-psychotic disorders (r=-0,49; p<0,1) and behavioral disorders and personality disorders in adults (r=-0,75; p<0,05) with poverty of the population was typical. In Far East we have revealed negative interrelationships of prevalence of organic non-psychotic disorders (r=-0,51; p<0,05) and neurotic, stress-related and somatoform disorders (r=-0,54; p<0,05) with cash incomes.
1882 – The Association Between Post-stroke Depression And Mortality: a Metaanalysis
Authors: Bartoli F. , Lillia N. , Lax A. , Crocamo C. , Mantero V. , Pini E. , Carrà G. , Agostoni E. , Clerici M. 
Published: July 2013

IntroductionStroke represents the third most frequent cause of mortality in developed countries, following only coronary heart diseases and cancer. Post-Stroke Depression (PSD) is extremely common among stroke survivors, and it may have great burden on the likelihood of functional recovery and long-term outcomes. We hypothesized that PSD is related to a higher rate of mortality among people suffering from a stroke.AimTo estimate the risk of mortality among subjects suffering from PSD as compared with stroke survivors who did not suffer from PSD.MethodsWe performed a systematic review of papers indexed in Pubmed. Both fixed and random-effects methods for estimating association and time-to-event pooled effects were used. The presence and the level of heterogeneity were assessed using Q test and I2 statistic.ResultsSeven papers had data suitable for meta-analysis. The pooled association effect for mortality at follow-up in people with PSD were statistically significant (p< 0.05). The time-to-event estimation showed a statistically significant correlation exclusively under the fixed effect analysis.ConclusionsThese findings pointed out the potential burden of PSD on post stroke mortality. Further investigation is required to clarify the nature of PSD/mortality association.