bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mood Disorder Questionnaire Positivity in Systemic Lupus Erythematosus and Other Chronic Diseases including Screen Bipolar Disorders or Rhythm and Energy Dysregulation Syndromes (DYMERS)
Authors: Primavera Diego , Fornaro Michele , Carrà Giuseppe , Romano Ferdinando , Aviles Gonzales Cesar Ivan , Preti Antonio , Sancassiani Federica , Cossu Giulia , Nardi Antonio Egidio , Scano Alessandra , Orrù Germano , Chessa Elisabetta , Floris Alberto , Piga Matteo , Cauli Alberto , Carta Mauro Giovanni 
Published: August 2024

Introduction
This study explores the issue of paper-and-pencil screening tests for bipolar disorder, often leading to false positives. It discusses hypotheses that connect MDQ positivity with sleep disorders, a decline in health-related quality of life, and the impact of the COVID-19 pandemic on mood disorders. The study proposes that MDQ identifies a “Dysregulation of Mood, Energy, and Social Rhythms Syndrome” (DYMERS), indicating a stress-related condition. It aims to investigate the association between MDQ positivity and systemic lupus erythematosus (SLE) in comparison to other chronic disorders.

Methods
This case-control study, conducted from April 2019 to February 2020, investigated MDQ positivity in patients with SLE. Ethical approvals were obtained, and statistical analysis was used for data assessment.

Results
This is a case-controlled study where MDQ positivity was significantly higher in systemic lupus erythematosus cases than controls. The analysis compared gender, age, and the presence of depressive episodes between MDQ-positive and MDQ-negative cases, revealing some differences but no significant variations. Interestingly, no association with high prednisone or biologics use was observed. The frequency of MDQ positivity in systemic lupus erythematosus was compared to other chronic pathologies, revealing varying associations with each condition.

Conclusion
This study reveals a high rate of (MDQ) positivity in systemic lupus erythematosus (SLE), associated with the risk of bipolar disorder in SLE. Notable discrepancies in MDQ positivity risk factors between SLE and bipolar disorder are observed. The study emphasizes the ability of MDQ to identify a distinct syndrome characterized by rhythm dysregulation, posing a risk for bipolar disorder and other disorders.
Assessment of Eye Care Apps for Children and Adolescents Based on the Mobile App Rating Scale: Content Analysis and Quality Assessment
Authors: Liu Ming , Wu Xiaoqian , Li Ziyu , Tan Dongmei , Huang Cheng 
Published: August 2024

Background
In China, the current situation of myopia among children and adolescents is very serious. Prevention and control of myopia are inhibited by the lack of medical resources and the low awareness about eye care. Nevertheless, mobile apps provide an effective means to solve these problems. Since the health app market in China is still immature, it has become particularly important to conduct a study to assess the quality of eye-care apps to facilitate the development of better eye-care service strategies.

Objective
This study aimed to evaluate the quality, functionality, medical evidence, and professional background of eye-care apps targeting children and adolescents in the Chinese app stores.

Methods
A systematic search on iOS and Android app stores was performed to identify eye-care apps for children and adolescents. The general characteristics, development context, and functional features of the apps were described. Quality assessment of the apps was completed by 2 independent researchers using the Mobile App Rating Scale.

Results
This study included 29 apps, of which 17 (59%) were developed by commercial organizations and 12 (41%) had a design with relevant scientific basis. The main built-in functions of these apps include self-testing (18/29, 62%), eye exercises (16/29, 55%), and eye-care education (16/29, 55%). The mean overall quality of eye-care apps was 3.49 (SD 0.33), with a score ranging from 2.89 to 4.39. The overall Mobile App Rating Scale score exhibited a significant positive correlation with the subscale scores (r=0.81-0.91; P<.001). In addition, although most apps provided basic eye-care features, there are some deficiencies. For example, only a few apps were developed with the participation of medical organizations or professional ophthalmologists, and most of the apps were updated infrequently, failing to provide the latest eye-care information and technology in a timely manner.

Conclusions
In general, the quality of eye-care apps for children and teenagers in Chinese app stores is good. These apps fulfill users’ needs for eye-care services to a certain extent, but they still suffer from insufficient medical background, low user engagement, and untimely updates. In order to further improve the effectiveness of eye-care apps, cooperation with medical institutions and professional ophthalmologists should be strengthened to enhance the scientific and authoritative nature of the apps. At the same time, interactive features and regular updates should be added to enhance user participation and the continuity of the apps. This study provides a reference for future development or improvement of eye-care apps, which can help promote myopia prevention and control.
Racial Composition of Social Environments Over the Life Course Using the Pictorial Racial Composition Measure: Development and Validation Study
Authors: Bather Jemar R , Kaphingst Kimberly A , Goodman Melody S 
Published: August 2024

Background
Studies investigating the impact of racial segregation on health have reported mixed findings and tended to focus on the racial composition of neighborhoods. These studies use varying racial composition measures, such as census data or investigator-adapted questions, which are currently limited to assessing one dimension of neighborhood racial composition.

Objective
This study aims to develop and validate a novel racial segregation measure, the Pictorial Racial Composition Measure (PRCM).

Methods
The PRCM is a 10-item questionnaire of pictures representing social environments across adolescence and adulthood: neighborhoods and blocks (adolescent and current), schools and classrooms (junior high and high school), workplace, and place of worship. Cognitive interviews (n=13) and surveys (N=549) were administered to medically underserved patients at a primary care clinic at the Barnes-Jewish Hospital. Development of the PRCM occurred across pilot and main phases. For each social environment and survey phase (pilot and main), we computed positive versus negative pairwise comparisons: mostly Black versus all other categories, half Black versus all other categories, and mostly White versus all other categories. We calculated the following validity metrics for each pairwise comparison: sensitivity, specificity, correct classification rate, positive predictive value, negative predictive value, positive likelihood ratio, negative likelihood ratio, false positive rate, and false negative rate.

Results
For each social environment, the mostly Black and mostly White dichotomizations generated better validity metrics relative to the half Black dichotomization. Across all 10 social environments in the pilot and main phases, mostly Black and mostly White dichotomizations exhibited a moderate-to-high sensitivity, specificity, correct classification rate, positive predictive value, and negative predictive value. The positive likelihood ratio values were >1, and the negative likelihood ratio values were close to 0. The false positive and negative rates were low to moderate.

Conclusions
These findings support that using either the mostly Black versus other categories or the mostly White versus other categories dichotomizations may provide accurate and reliable measures of racial composition across the 10 social environments. The PRCM can serve as a uniform measure across disciplines, capture multiple social environments over the life course, and be administered during one study visit. The PRCM also provides an added window into understanding how structural racism has impacted minoritized communities and may inform equitable intervention and prevention efforts to improve lives.
Mapping Knowledge Landscapes and Emerging Trends in AI for Dementia Biomarkers: Bibliometric and Visualization Analysis
Authors: Qi Wenhao , Zhu Xiaohong , He Danni , Wang Bin , Cao Shihua , Dong Chaoqun , Li Yunhua , Chen Yanfei , Wang Bingsheng , Shi Yankai , Jiang Guowei , Liu Fang , Boots Lizzy M M , Li Jiaqi , Lou Xiajing , Yao Jiani , Lu Xiaodong , Kang Junling 
Published: August 2024

Background
With the rise of artificial intelligence (AI) in the field of dementia biomarker research, exploring its current developmental trends and research focuses has become increasingly important. This study, using literature data mining, analyzes and assesses the key contributions and development scale of AI in dementia biomarker research.

Objective
The aim of this study was to comprehensively evaluate the current state, hot topics, and future trends of AI in dementia biomarker research globally.

Methods
This study thoroughly analyzed the literature in the application of AI to dementia biomarkers across various dimensions, such as publication volume, authors, institutions, journals, and countries, based on the Web of Science Core Collection. In addition, scales, trends, and potential connections between AI and biomarkers were extracted and deeply analyzed through multiple expert panels.

Results
To date, the field includes 1070 publications across 362 journals, involving 74 countries and 1793 major research institutions, with a total of 6455 researchers. Notably, 69.41% (994/1432) of the researchers ceased their studies before 2019. The most prevalent algorithms used are support vector machines, random forests, and neural networks. Current research frequently focuses on biomarkers such as imaging biomarkers, cerebrospinal fluid biomarkers, genetic biomarkers, and blood biomarkers. Recent advances have highlighted significant discoveries in biomarkers related to imaging, genetics, and blood, with growth in studies on digital and ophthalmic biomarkers.

Conclusions
The field is currently in a phase of stable development, receiving widespread attention from numerous countries, institutions, and researchers worldwide. Despite this, stable clusters of collaborative research have yet to be established, and there is a pressing need to enhance interdisciplinary collaboration. Algorithm development has shown prominence, especially the application of support vector machines and neural networks in imaging studies. Looking forward, newly discovered biomarkers are expected to undergo further validation, and new types, such as digital biomarkers, will garner increased research interest and attention.
Corporate Social Responcibility PT. Astra Internasional Mewujudkan Ketahanan Sosial Melalui Program Wisata Tiga Agama Kota Tua Jamblang Kabupaten Cirebon Provinsi Jawa Barat
Authors: Chamidah Nurul 
Published: August 2024

ABSTRAKPenelitian ini bertujuan untuk menggali potensi dari kawasan Jamblang melalui program corporate social responsibility PT. Astra Internasional sebagai program pemberdayaan masyarakat bidang desa wisata. Titik utama pengembangan melalui modal sosial masyarakat serta analisis atas penilaian destinasi Kota Tua Jamblang. Jamblang memiliki destinasi yang tidak dimiliki di tempat lain yaitu kerukunan umat beragama sebagai atraksi utama. Kawasan Jamblang menampilkan tiga agama yakni Islam, Kristen dan Kong Hu Chu dan desain arsitektur tiga etnis. Penelitian ini menggunakan pendekatan kualitatif yang menitikberatkan peneliti sebagai instrument utama. Pengumpulan data berupa observasi partisipan yang berarti peneliti ikut masuk dan terlibat dalam semua kegiatan mulai dari tahun 2018 hingga 2023, studi literatur diperoleh dari literatur tutur budayawan serta dokumen dan wawancara dengan manajer Environment Social Responcibility PT. Astra Internasional, Presiden Direktur Grow Up Institute, Kepala Desa Jamblang dan aktor penggerak desa wisata Kota Tua Jamblang. Ketahanan sosial berupaya menjadikan permasalahan menjadi peluang serta kebermanfaatan dirasakan oleh masyarakat. Rangkaian sejarah dan peninggalan bangunan tua menjadi modal bagi masyarakat sebagai destinasi wisata dengan konsep wisata edukasi. Corporate Sosial Responcibility PT. Astra Internasional melalui Desa Sejahtera Astra (DSA) melakukan program pendampingan berupa desa wisata dengan tema Kota Tua Jamblang. Grow Up Institute selaku fasilitator pelaksana di lapangan menjadikan ketahanan sosial yang didasari penghormatan ritual para pemeluk agama serta konten mural sebagai atraksi wisata bertema budaya, nasionalisme dan kepedulian lingkungan. Upaya yang dilakukan meliputi tiga tahap program yakni membuat konsep dasar pengembangan Kota Tua Jamblang pada kerukunan umat beragama, nasionalisme dan lingkungan; Inklusi, pendampingan pada aktor masyarakat guna menumbuhkan kesadaran dan kemauan untuk peduli pada lingkungan tempat tinggal serta menjadi peluang wisata; Stimulus dilakukan dengan melakukan rekayasa wisata setiap akhir pekan dengan menampilkan seni dan budaya lokal; dan tujuan utama adalah kemandirian masyarakat dalam upaya menjadikan Jamblang sebagai laboratorium sosial budaya kerukunan umat beragama.
Peran Negara G20 dalam Percepatan Transisi Energi Baru Terbarukan (EBT) untuk Mewujudkan Ketahanan Energi Nasional
Authors: Rizky Lucitania , Pratiwi Tiffany Setyo , Wibawa Adi , Achdiyana Isna 
Published: August 2024

ASBTRACT This research discussed international influences, especially G20 member countries in accelerating the national energy transition to realizing national energy resilience, according to the mandate of the established rules. The approach used in this study is an intermestic model approach which provides a pattern of the influence of international interests and global ideas in mapping the domestic political agenda, namely the energy transition as a priority issue. The research method used is a qualitative approach with data collection techniques and in-depth interviews with the Directorate General of Multilateral Cooperation, Ministry of Foreign Affairs of the Republic of Indonesia.The results of the study show that the acceleration of the Net Zero Emission (NZE) 2060 Roadmap is related to the intermestic idea that international support and assistance patterns have an impact on national energy resilence.
Strategi Empat Pilar Kebangsaan Bagi Pembangunan Generasi Muda Dalam Menyongsong Bonus Demografi dan Implikasinya Terhadap Ketahanan Sosial Kepulauan Riau
Authors: Soesatyo Bambang 
Published: August 2024

ABSTRACT The Demographic Bonus is a golden opportunity for the Indonesian nation. However, the existing social problems due to limited workforce pose a threat to this opportunity. Through the reconstruction of the Four Pillars of the Nation: (Pancasila, UUD 1945, Negara Kesatuan Republik Indonesia and Bhinneka Tunggal Ika) strengthening of the younger generation is implemented as a preventive measure and societal understanding. The research aims to determine how the Four Pillars of the Nation strategy is implemented for the development of the younger generation in facing the Demographic Bonus and its implications for the social resilience of the Riau Islands. Using a descriptive qualitative approach, the research informants involve academics, community leaders, youth figures, government, and private employees, as well as students. The results show that the Riau Islands Government strives through the Demographic Bonus and the strengthening of national values, but the threat of national disintegration arises. The socialization of the Four Pillars of the Nation needs improvement, especially among teachers and community leaders. Protection for communities vulnerable to human trafficking is carried out through the Trauma Center Protection House (RPTC) with the formation of a social network involving the TPPO Task Force and the Provincial Task Force. Challenges related to financial motivation and economic inequality still exist. The Four Pillars of the Nation are implemented as education on national values, and conflict resolution involves communication and sometimes legal approaches. Collaboration between the TPPO Task Force, the community, and community leaders is expected to reduce the risk of human trafficking in this province.
Inversión Sostenible
Authors: Adriano Miñope Diana Teresa , Charaja Alagón Keidy Luz , Mamani Mamani Stephani Belinda 
Published: August 2024

La inversión sostenible ha adquirido una relevancia significativa a nivel global, impulsada por las consecuencias del cambio climático y la devastación ambiental causada por la explotación excesiva de recursos naturales no renovables. Esta creciente preocupación ha motivado a las empresas a comprometerse cada vez más con la sostenibilidad, generando impacto tanto en sus prácticas de Responsabilidad Social Empresarial como en la formulación de políticas gubernamentales. Este compromiso se tradujo en una creciente demanda de inversiones sostenibles, las cuales tenían como objetivo generar un impacto positivo en el medio ambiente y la sociedad. El objetivo primordial de este artículo fue analizar el impacto a largo plazo de las inversiones sostenibles en la rentabilidad de los proyectos. Para lograrlo, se llevó a cabo una exhaustiva revisión sistemática de la literatura, abarcando información relevante, teorías existentes, investigaciones previas y datos pertinentes. Los resultados obtenidos indicaron que las inversiones sostenibles podían tener un impacto positivo significativo. Por un lado, las empresas comprometidas con la sostenibilidad solían ser más rentables al reducir costos operativos y aumentar sus ventas. En conclusión, la aplicación de las finanzas verdes en estas inversiones se destacaba como una estrategia de “ganar-ganar”. No solo generó un impacto favorable en el medio ambiente, sino que también tenía el potencial de fortalecer la fidelización del consumidor. A pesar de estos beneficios, era crucial reconocer que las inversiones sostenibles podían conllevar un mayor riesgo, requiriendo una evaluación meticulosa antes de tomar decisiones de inversión.
Efek Pemberian Tetes Mata Diquafosol Sodium 3% Sebelum Kegiatan Tatap Layar terhadap Kejadian Mata Kering pada Laki-laki Muda
Authors: Kurniawan Chalid , Ewangga Bayu , Karyana Mey M. 
Published: August 2024

Kegiatan tatap layar yang lama akan meningkatkan kemungkinan terjadinya sindrom mata kering karena stabilitas komponen air mata berkurang. Penggunaan air mata buatan seperti diquafosol sodium dapat membantu mengatasi masalah mata kering. Tujuan penelitian adalah menilai perbedaan gejala subjektif dan tanda objektif mata kering pada kelompok pengguna diquafosol sodium sebelum melakukan kegiatan tatap layar dibandingkan kelompok kontrol. Penelitian ini menggunakan desain potong lingkang dengan subjek laki-laki muda 44 orang yang memenuhi kriteria inklusi dan tidak memenuhi kriteria eksklusi. Subjek dipilih secara acak kemudian dibagi dua kelompok. Penelitian dilakukan di Garut dari Oktober hingga Desember 2022. Dilakukan pemeriksaan Schirmer sebelum dan sesudah kegiatan tatap layar serta pengisian kuesioner mata kering. Kelompok intervensi mendapatkan diquafosol sodium sebelum kegiatan tatap layar sedangkan kelompok kontrol tidak mendapatkan. Data dianalisis dengan t-test atau Mann Whitney. Hasil penelitian menunjukkan terdapat perbedaan bermakna uji Schirmer setelah kegiatan tatap layar antar dua kelompok dan perbedaan bermakna hasil selisih uji Schirmer sebelum dan setelah kegiatan tatap layar. Analisis kuesioner menunjukkan hanya satu responden mengalami gejala mata kering pada kelompok intervensi dibandingkan 7 orang pada kelompok kontrol. Penelitian ini menunjukkan bahwa penggunaan air mata buatan diquafosol sodium efektif mencegah terjadinya sindrom mata kering sebelum kegiatan tatap layar.
Correlation between Atherogenic Index of Plasma and Lipid Profile with Cognitive Function and Their Effect on Outcome in Ischemic Stroke Patients
Authors: Fitri Fasihah Irfani , Zulfikri Muhammad 
Published: August 2024

Dyslipidemia is one of the main risk factors for both ischemic stroke and cognitive impairment. Atherogenic index of plasma (AIP) has been shown to correlate with mortality and clinical outcomes in stroke, but studies about its association with cognitive impairment in ischemic stroke is still limited. We aimed to determine the correlation between AIP and lipid profile and cognitive function and their effect on outcome in ischemic stroke patients. A cross-sectional study involving 50 ischemic stroke patients in the Haji Adam Malik General Hospital was conducted from August 2021 to March 2022. We measured the cholesterol level and calculated the AIP then divided them into 3 risk categories which were high (AIP>0.21); intermediate (AIP>0.11and ≤0.21) and low (≤0.11). We performed cognitive assessment and stroke outcome at the 7th day of stroke onset. Data analysis was conducted with Spearman correlation test. The subjects were predominantly male (60%) with median age of 55 (34-68) years. Most of the subjects had AIP level of high risk (54%) and were cognitively impaired (66%). There was no significant association between AIP and both global cognition and each cognitive domain. However, there were significant negative correlations between total cholesterol (r=-0.31, p=0.03) and LDL-C level (r=-0.30, p=0.03) and attention. There was also a significant negative correlation between cognitive function and stroke outcome (r=-0.61, p=0.01). Higher total cholesterol and LDL-C levels showed negative correlation with cognitive function, mainly attention. Poorer cognitive function correlated with worse outcome in ischemic stroke patients.
Epistemologi Ibnu Khaldun dan Relevansinya Terhadap Kurikulum Pendidikan Agama Islam di Indonesia
Authors: Nurlaila Sri Wisnu Nugraha , Rojab Taufik Fahrul , Agustin Usman 
Published: August 2024

Tulisan ini bertujuan untuk mengungkap konsep epistemologi yang ditawarkan oleh Ibnu Khaldun tentang Pendidikan dan relevansinya terhadap kurikulum Pendidikan Agama Islam di Indonesia. Metode yang di gunakan dalam tulisan ini adalah analisis deskriptif kualitatif, dengan melalui studi literatur terhadap dokumen maupun teks-teks penelitian sebelumnya, ditemukan bahwa secara teoritis ada sedikit relevansi antara kurikulum yang digagas oleh Ibnu Khaldun dengan kurikulum yang dikembangkan dalam Pendidikan Islam di Indonesia yaitu di bidang klasifikasinya, namun ada perbedaan dalam bidang mata pelajaran yang dikembangkan secara fundamental, Ibnu Khaldun menegaskan bahwa adanya klasifikasi ilmu pengetahuan tidak menimbulkan dikotomi ilmu antara kelompok naqqliyah dan aqliyah.
Paradigma Filosofis Integrasi Keilmuan Berdasarkan Refleksi Historis Perguruan Tinggi Keislaman
Authors: Sari Maya 
Published: August 2024

Paradigma integrasi keilmuan tidak serta merta dapat diterima dan terimplikasi dengan baik pada level UIN di PTKI. Begitu banyak permasalahan yang timbul dalam penerapannya sehingga penelitian ini bertujuan untuk; menganalisis sejarah PTKI di Indonesia sebagai upaya penemuan paradigm keilmuan yang berkembang; menganalisasi bagaimana anomali pemikiran mulai terjadi; mendeskripsikan bagaimana paradigma baru berkembang; serta mengetahui implikasi terhadap paradigma tersebut. Penelitian ini menggunakan studi literatur untuk menyusun narasi analisis. Thomas Khun mengajarkan tentang arti paradigma, sekalipun ide besarnya mengkritik tentang kebenaran ilmu yang bersifat doktrinasi. Dalam hal ini pandangan ilmu agama sama sekali tidak dapat dipaksakan dalam merefleksikan paradigma integrasi keilmuan. Akan tetapi Lakatos mampu menawarkan konsep “Program Riset” untuk meninjau bahwa keilmuan agama adalah hardcore yang sifatnya mutlak dan mesti dilindungi oleh falsifikasi. Berbalutkan Protective Belt sebagai analogi keilmuan yang lain, maka dapat dilihat bagaimana implementasi integrasi keilmuan berbasis keagaamaan secara sederhana tergambar pada filosofis Lakatos.