bluuebunny/crossref_metadata_2025_split huggingface dataset:
1947 – “Deja Vu” Fenomena In Psychosis -case Report
Authors: Barac-Otasevic Z.V. , Vujisic S. , Mastilovic-Cukovic R. 
Published: July 2013

Deja Vu is a sense that something has already suffered from before, or have someone from before and seen the like. In casual conversation with someone you can get this deja vu feeling that you have something to talk to or work, have seen or experienced.In this article the authors describe a patient who is a phenomenon of deja vu was the introduction to the first psychotic episodeAdditional tests are sent to a neurologist, and there werw changing in the EEG and neurologist started to treat him by antiepileptic drug, and monitored regularly.First EEG showed bilateral acticvity a little more left FC.Working together psychiatrist and neurologist treated by regular medication the patient is now in a satisfactory clinical remission status.
1951 – The Role Of Self-transcendence In Personality And Its Impact On Quality Of Life
Authors: Minodora M.M. , Herta D.C. , Cozman D.M.C. 
Published: July 2013

IntroductionThe concept of person is connected to personality and self-transcendence belongs to its structure, as core component. The assessment of self-transcendence as part of human personality opens the gate of self-awareness in personology. Robert Cloninger is a distinctive researcher because he states that the comprehensive assessment of the human being includes the moral-spiritual dimension which implies deep self-awareness, in the absence of which subjective well-being is not possible.Thus, in Cloninger's view self-transcendence is a character dimension. Self-transcendent individuals are often described as un-demanding, fulfilled, enduring, creative, altruistic, spiritualized. High self-transcendence has adaptive advantages when the individuals deals with suffering and death, which are inevitable once the person grows older.Material and method131 patients with personality disorder aged 19 to 62 were included in the study. Temperament and Character Inventory; Multicultural Quality of Life Index (J. Mezzich et all, 2000).Specific objective of the studyThe assessment of the relationship between the scores in personality dimensions and the quality of life.ResultsSignificant correlations were ascertained between the character dimension Self-transcendence and the Multicultural Quality of Life Index. Thus, according to this correlation analysis, (r2 = 0,035) of the variation of the score on the Multicultural Quality of Life Index is given by variations of the Self-Transcendence score.ConclusionsThe assessment of the self-transcendence dimension as part of human personality opens the doors of knowledge in personology.Human personality directly influences scores in quality of life scales through character dimensions.
1953 – Professional Burnout Syndrome Among Intensive Care Physicians In Salvador, Brazil
Authors: Andrade-Nascimento M. , Barros D.S. , Nascimento Sobrinho C.L. 
Published: July 2013

IntroductionBurnout syndrome is a response to prolonged occupational stress that involves three main dimensions: emotional exhaustion, depersonalization, and reduced personal accomplishment. There are few studies on burnout doctors in Brazil.Objectives/aimsTo describe the prevalence of burnout syndrome among intensive care physicians in Salvador, Brazil, and analyze it for associations with demographic data and aspects of their working conditions (psychological demands and control over tasks).MethodsThis was a cross-sectional study investigating associations between psychosocial aspects of work and professional burnout in a population of 297 intensive care physicians in Salvador. A self-administered individual questionnaire was used to collect data on psychosocial features of work using the demand-control model (Job Content Questionnaire) and on the mental health of the physicians using the Maslach Burnout Inventory (MBI).ResultsAn elevated level of working hours overload and on-call work overload was observed. The prevalence of professional burnout was 7.4% and was more strongly associated with the psychological demands of work than with intensive care physician's control over that work.ConclusionsPhysicians doing highly demanding work (many demands and little control) suffered 10.2 times more burnout than those with undemanding work (few demands and a high degree of control).
1955 – Aspects Of Disbalance Macro- And Microelements In Children With Autism Spectrum Disorders In Belarus
Authors: Dokukina T.V. 
Published: July 2013

IntroductionDetermination of macro-and microelements disbalance in children with autism spectrum disorders (ASD) provides us with opportunity to understand the etiology and pathogenesis.ObjectivesWe performed research on the macro-and microelement status of 65 children with ASD and their parents. We investigated 130 samples of hair (65 children: 18 girls and 47 boys and 65 parents).AimsThe purpose of this study was to identify and determine the nature of the disbalance of macro-and microelements of children with ASD in Belarus.MethodsAs a biological substrate we used hair. For carrying out researches using a laser multi-atomic emission spectrometer LSS-1.ResultsDiselementose on aluminum in 35.4% of the children and their parents 33.85%. Calcium in children found in 100% a deficiency. Iron content occurred in 50.8% children, and in 65% parents. In 26.1% children and parents 13% had a deficiency. 23.1% children and 18.5% parents had diselementose towards above norma. Copper content found in 87.7%, a deficiency in children and parents. Excess of the level occurred in 4.6% among parents and 7.7% among children. In 55.3% children have zinc deficiency. Reduction of zinc was noted and the parents in 44.6%. Exceeding concentration of zinc was noted in 7.7% in children and in 10.8% among parents.ConclusionsDiselementose had children with ASD and parents. Given that the change in the content of copper and zinc is an indirect marker of the exchange protein metallothionein suggests violation of the content of this protein, which is alleged etiopathogenetic factor for ASD.
1956 – Comparison Of Serum Prolactine Levels Between Risperidone And Paliperidone Extended-release In Female Patients With Schizophrenia
Authors: Albayrak Y. , Beyazyuz M. , Öztürk N. , Binbay Z. , Kuloğ lu M. 
Published: July 2013

IntroductionPaliperidone extended-release (ER) is an atypical antipsychotic that presents the active metabolite of risperidone (9-hydroxyrisperidone) using OROS® technology [1]. Multinational placebo-controlled studies have shown paliperidone ER 3- 15 mg/day to be both efficacious and safe, with discontinuation rates due to adverse events (AEs) similar to placebo [2].MethodsSeventy-eight female patients who were diagnosed as schizophrenia according to DSM-IV-TR and who were started on the treatments of risperidone or paliperidone included to present study. The serum prolactine levels were measured before and after 5 weeks of treatment.ResultsThe 35 of patients were treated with paliperidone, while 43 patients were given oral risperidone treatment. The increases in serum prolactine levels were significant in both groups (p≤0.001), however the increase was much more in paliperidone group. Furthermore, discontinuation rates due to indirect effects of prolactine increase such as galactorrhea, amenorrhea were higher in paliperidone group compared with risperidone group.DiscussionBeside the efficacy and well tolerability of paliperidone extended-release, the increase of prolactine level and associated side effects should be carefully assessed during treatment specifically in young women patients.
1957 – Study Of Paraoxonase 1 Activity In Tunisian Bipolar 1 Patients Treated With Thymoregulators
Authors: Ezzaher A. , Haj Mouhamed D. , Hellara I. , Neffati F. , Mechri A. , Douki W. , Gaha L. , Najjar M.F. 
Published: July 2013

IntroductionParaoxonase (PON), an enzyme, is a key process in the pathophysiology of atherosclerosis.AimsWe aim to investigate the variations of PON1 activity in Tunisian bipolar I patients treated with thymoregulators.Patients and methodsOur study included 78 patients with bipolar I disorder, diagnosed according to the DSM-IV, and 64 controls aged 35.97±11.55 years and 36,31±18.26 years respectively. 41 patients were treated by valproic acid, 16 under carbamazepine and 21 under lithium. PON1 activity was determined by kinetic methods using Konelab 30 equipment.ResultsCompared to controls, patients treated by thymoregulators had a significantly lower paraoxonase activity (p=0.004). Furthermore, PON1 was significantly correlated with c-HDL values (r=0.5612; P< 0.001). The lowest PON1 levels were noted in patients treated with lithium (150±94UI/L) and the highest levels were showed in those under carbamazepine (260±185UI/L), but this difference was not significant. In patients under lithium, we showed that this parameter was significantly lower when illness duration was more than 12 years, the lithium posology exceeds 1000 mg/day and the lithium plasmatic concentrations were more than 0.54 mmol/L. However, there was no significant difference among gender, age, cigarette smoking and alcoholic beverage.ConclusionsBipolar patients had a significant decrease in PON1 activity that contributes to increased risk of cardiovascular diseases. This perturbation could be related to treatment with thymoregulators and particularly lithium. Therefore, such patients should require specific care and clinics should track the effects of treatment on physical and biological parameters, and should facilitate access to appropriate medical care.
1958 – Efficacy Of Modified Compliance Therapy For Schizophrenia Patients
Authors: Omranifard V. , Achochachian S. , Maracy M.R. 
Published: July 2013

BackgroundSchizophrenia requires a large share of medical resources due to its early onset and chronic and severe nature. Compliance therapy is a therapy specifically designed to improve concordance with treatment for those with major mental illnesses. The aim of present study was to determine whether compliance therapy improves drug adherence and consequently makes better global functioning and improves quality of life in schizophrenic patients.MethodsThis randomized controlled clinical trial study was done in Noor hospital in 2008-2009. Patients were randomly assigned to receive the intervention consisting of 8 sessions of compliance therapy, or the control treatment consisting of an equal number of sessions of supportive counseling. All patients were evaluated by Heinrichs Quality of Life scale, Global Assessment of Functioning (GAF) scale, and Positive and Negative Symptoms Scale (PANSS) at baseline, third month and sixth month follow-up after intervention.Results76 schizophrenic patients who met criteria of study were enrolled in the trial. Our data showed a significant main effect for interaction of group and time for GAF scale, Heinrichs Quality of Life scale and PANSS.ConclusionsThe findings of our study showed that compliance therapy can improve not only global functioning but also quality of life in schizophrenic patients. In addition, PNASS was improved during the six months follow up in compliance therapy group.
1962 – Community Mental Health Competence - Mutual Association
Authors: Ferreira J.S. , Martins M. 
Published: July 2013

The majority of the European Countries are facing the challenge to address the very high prevalence of mental disorders with limited mental health resources. Some of them drafted mental health strategies with community based models of care with the aim to give the best care as possible. Mutualista Association is the largest Portuguese mutual association, one of the largest mutual associations in Europe. Is also a reference as an institution in the social economy sector and financial activity in Portugal. The commitment with all the mutual association members brings to the institution importante and unique solidarity values.The authors reflect about the psychiatric response of the Mutualidade Terras de Santa Maria to the psychiatric community patients attending the Clinic. The project gives “voice” to a vulnerable communitie perceived as a “receptive social environment” and emphasise the need for greater attention to the impacts of context, culture and local resources on people's responses to adversity and illness. They present a social-demographic characterization of the population attended as well as local strategies put in action to the various clinical situations.The authors highlight the role of potential partnerships such as National Health System and Community Groups that are able to recognize better their communities's needs and assist them in working for improved well-being. Respectful local-global alliances have a key role to play in this process.
1965 – Corticosteroid-induced Mania Treated With Risperidone - a Case Report
Authors: Almeida T. , Araújo F. , Rodrigues J.D. , Venâncio Â. , Horta A. , Monteiro A.L. , Lapa G. , Bouça J. 
Published: July 2013

IntroductionCorticosteroids have either somatic and psychiatric side effects. Somatic adverse effects are well described while neuropsychiatric have received less attention. Psychiatric symptoms such as depression, psychosis and especially mania are common side effects of corticotherapy.Aims and objectivesDescribe a case of a 53 year old female patient, with no psychiatric history, who developed psychiatric symptoms during the treatment of an acute exacerbation of multiple sclerosis with large parenteral doses of corticosteroids. Three days after the onset of corticotherapy she developed increased energy, elevated mood, increased motor activity, racing thoughts, and diminished need for sleep. She subsequently developed grandiose and persecutory ideation and then feared her grandson was going to die. This lead to her admission to psychiatric unit of our hospital to address this behavioral problems. Her husband noticed that she had become “hyper” in the past when she received pulse corticosteroid therapy, but the most recent episode was by far the worst.MethodsRevision of the scientific literature through Pubmed, Embase and Psychinfo using search terms including corticosteroids, mania, depression, psychosis and mood.ResultsPrednisone was suspended and Risperidone 2 mg was begun for presumed steroid-induced mood disorder, and the patient became calmer and much less guarded over the next 2-3 days. After a week she recovered complete euthymic mood and reverted to normal functioning.ConclusionsThese data suggest that Risperidone is well tolerated and appears to be useful for mood disturbances associated with corticosteroid therapy. Controlled trials seem warranted to confirm these observations.
1966 – A Wrong Body: a Neuroscience Perspective On The Etiology Of Anorexia Nervosa
Authors: Gaudio S. , Riva G. 
Published: July 2013

Anorexia nervosa (AN) patients have a disturbance in the way in which one's body is experienced and perceived: they evaluate negatively their own body and body parts and deny the seriousness of their current low body weight. It is controversial whether these symptoms are secondary to dysfunctions in the neuronal processes related to appetite and emotionality or reflect a primary disturbance in the way the body is experienced and remembered. Our spatial experience is organized around two different reference frames - egocentric (body as reference of first-person experience) and allocentric (body as object in the physical world) - that influence each other during the interaction between long- and short-term memory processes in spatial cognition.Neuroimaging studies on AN patients showed several structural and functional alterations in frame and memory-related bodyimage-processing brain circuits. Particularly, both structural and functional studies showed alterations of the precuneus and the inferior parietal lobe. These alterations may be related to the etiology of the body image distortion: individuals with AN are locked to an allocentric (observer view) negative memory of the body that is no more updated by contrasting egocentric representations driven by perception.
1973 – The Role Of Comorbid Anxiety Disorder In The Outcome Of Bipolar i Disorder
Authors: Andrade-Nascimento M. , Miranda-Scippa A. , Telles C.A.S. , Rocha M. , Nery-Fernandes F. , Pettersen K.C. , Daltro-Oliveira R. , Leite C.R. , Kapczinski F. , Quarantini L.C. 
Published: July 2013

IntroductionBipolar disorder (BD) commonly co-occurs with anxiety disorders (AD) and this comorbidity has been associated to worse clinical outcomes in BD patients. However frequency and clinical outcomes data might be biased once some of them had been originated from acutely ill bipolar patients as well as those in remission.Objectives/aimsTo assess AD in bipolar sample in order to know if this frequency vary according illness phase and identify possible clinical outcomes related to this comorbidity.MethodsA population of 355 outpatients with bipolar I disorder were evaluated using structured instruments (SCID). The sample was split into four groups considering the illness phase and the presence of AD: euthymic without AD (euthymic/non- AD); euthymic with AD (euthimic/AD); non-euthymic without AD (non-euthymic/non-AD) and non-euthymic with AD (noneuthymic/ AD) groups. Clinical and socio-demographics differences between the groups were compared through bivariate analysis.ResultsThere was a progressive and significantly increasing in some worst clinical outcomes frequency, such as rapid cycling, suicide attempts, substance and alcohol use disorders, history of antidepressant use and decreased scores in all domains of QoL, from control group (euthymic /non-AD) through out intermediate group (non-euthymic/non-AD) until the group most affected (non-euthymic/AD). Both euthymic/non-AD and euthimic/AD groups did not differ.ConclusionsWe identified a group of severe bipolar patients that have worse clinical outcomes, and among them, the anxiety comorbidity. But, contrary to what has been stated, AD appears to be related with poor bipolar prognosis only when other severity clinical factors are presents.
1975 – Correspondence Among Emotional Regulation, Mentalization And Burn-out At Hungarian Health Care Workers
Authors: Fülöp E. , Devecsery Á. , Kurimay T. , Csabai M. 
Published: July 2013

IntroductionSeveral studies have shown that excessive emotional involvement of health care professionals may lead to burnout (Zapf et al 2001; Brotheridge&Grandey 2002). As our perevious studies (Fülöp, Devecsery & Csabai 2012) also showed, medical and paramedical professionals who are prone to overinvolve in the interactions of the patients experiencing distress, may suffer from emotional exhaustion for long run.ObjectiveWe looked for correlations between disturbances of emotional regulation, lack of mentalization, and intensive emotional distress.MethodsWe used a descriptive approach, where a set of questionnaires were applied. The sample consisted of 200 health care professionals - nurses, and assistents for oxyology-, from all over Hungary. Questionnaires used: Maslach Burnout Inventory, (Maslach and Jackson, 1986), Interpersonal Reactivity Index (Davis, 1980), Difficulties in Emotional Regulation Scale, (Gratz és Roemer, 2004) and Secondary Traumatic Stress Scale (Bride 2003). Our research team developed a test for mentatalization consists of 3 pictures of provider/patient interactions, and exposed with different instuctions according to 3 levels of mentalization.ConclusionOur preliminary results show that the “3-picture test”, as a global one, can be useful to measure the complexity of mentalization, its components, as spontaneous mentalization, emotional identification, and emotional anticipation. This test may help the further understanding of the relationships between emotional regulation and the phenomenon of burn-out.
1980 – Effect Of Cigarette Smoking On Insulin Resistance Risk
Authors: Haj Mouhamed D. , Ezzaher A. , Hellara I. , Neffati F. , Douki W. , Gaha L. , Najjar M.F. 
Published: July 2013

IntroductionSmoking is one of the main risk factors for cardiovascular disease (CVD). The mechanism(s) for the effects of smoking on CVD are not clearly understood; however, a number of atherogenic characteristics such as insulin resistance have been reported.AimsWe aim to investigate the effects of cigarette smoking on insulin resistance and to determine the correlation between this parameter with smoking status characteristics.MethodsThis study was conducted on 138 nonsmokers and 162 smokers aged respectively 35.55±16.03 and 38.47±21.91 years. All subjects are not diabetics. Fasting glucose was determined by enzymatic methods and insulin by chemiluminescence method. Insulin resistance (IR) was estimated using the Homeostasis Model of Assessment equation: HOMA-IR = [fasting insulin (mU/L) × fasting glucose (mmol/L)] /22.5. IR was defined as the upper quartile of HOMA-IR. Values above 2.5 were taken as abnormal and reflect insulin resistance.Results and discussionCompared to non-smokers, smokers had significantly higher levels of fasting glucose, fasting insulin and HOMA-IR index. A statistically significant association was noted between the smoking status parameters, including both the number of cigarettes smoked/day and the duration of smoking, and fasting insulin levels as well for HOMA-IR index. Among smokers, we noted a positive correlation between HOMA-IR index and both plasma thiocyanates and urinary cotinine.ConclusionThe findings show that smokers have a high risk to developing an insulin resistant, hyperinsulinaemic, compared with a matched group of non-smokers, and may help to explain the high risk of cardiovascular diseases in smokers.
1983 – Identifying Specific Domains Of Cognitive Dysfunction For Manic Episodes In Bipolar Affective Disorder
Authors: Vrabie M.I. , Miclutia I. , Marinescu V. , Popescu C. 
Published: July 2013

IntroductionThe recurrence of episodes of mania and/or depression is a feature of bipolar affective disorder and it interferes with neurocognitive performance.ObjectiveIdentifying specific domains of cognitive dysfunction for manic episodes in bipolar affective disorder.AimImproving life quality of bipolar patients with cognitive deficits.Methods60 bipolar (HAMD score >= 17, manic/hippomanic: YMRS score >= 12, euthymic: 6 month of remission, HAMD score < = 8, YMRS score < = 6) patients (DSM IV TR). The cognitive battery included standardized test of IQ, attention, working memory, visual memory, verbal memory and executive functioning. Demographic data, data about family history, psychiatric history, past/current treatment, history of psychosis, duration of illness, age of onset were collected. We analyzed statistically these data and identified specific domains of cognitive dysfunction for manic episode.ResultsStable and lasting cognitive impairments involving executive functioning (working memory, executive control, verbal fluency, mental manipulation and cognitive flexibility), verbal learning and memory and attention are evident across all phases of illness. Sustained attention (vigilance) is impaired in bipolar patients regardless of whether they are studied during periods of mania or depression. Performances on task that tapes domains of verbal learning and memory, and sustained attention were particularly impaired in manic patients.ConclusionsThere are persistent cognitive deficits over the course of bipolar affective disorder and specific cognitive impairment of each phase of the illness, like mania. This study identified several important risk factors that may moderate these cognitive deficits in manic patients.