bluuebunny/crossref_metadata_2025_split huggingface dataset:
Molecular Engineering of Methylated Sulfone‐Based Covalent Organic Frameworks for Back‐Reaction Inhibited Photocatalytic Overall Water Splitting
Authors: Zhang Xiang , Xiao Zhiwei , Jiao Lei , Wu Huyue , Tan Yan‐Xi , Lin Jing , Yuan Daqiang , Wang Yaobing 
Published: June 2024

AbstractSolar‐to‐hydrogen (H2) and oxygen (O2) conversion via photocatalytic overall water splitting (OWS) holds great promise for a sustainable fuel economy, but has been challenged by the backward O2 reduction reaction (ORR) with favored proton‐coupled electron transfer (PCET) dynamics. Here, we report that molecular engineering by methylation inhibits the backward ORR of molecular photocatalysts and enables efficient OWS process. As demonstrated by a benchmark sulfone‐based covalent organic framework (COF) photocatalyst, the precise methylation of its O2 adsorption sites effectively blocks electron transfer and increases the barrier for hydrogen intermediate desorption that cooperatively obstructs the PCET process of ORR. Methylation also repels electrons to the neighboring photocatalytic sulfone group that promotes the forward H2 evolution. The resultant DS‐COF achieves an impressive inhibition of about 70 % of the backward reaction and a three‐fold enhancement of the OWS performance with a H2 evolution rate of 124.7 μmol h−1 g−1, ranking among the highest reported for organic‐based photocatalysts. This work provides insights for engineering photocatalysts at the molecular level for efficient solar‐to‐fuel conversion.
Structural Modulation of Covalent Organic Frameworks for Efficient Hydrogen Peroxide Electrocatalysis
Authors: Wang Rui , Zhang Ziqi , Zhou Haiping , Yu Mingrui , Liao Li , Wang Yan , Wan Sheng , Lu Haiyan , Xing Wei , Valtchev Valentin , Qiu Shilun , Fang Qianrong 
Published: June 2024

AbstractThe electrochemical production of hydrogen peroxide (H2O2) using metal‐free catalysts has emerged as a viable and sustainable alternative to the conventional anthraquinone process. However, the precise architectural design of these electrocatalysts poses a significant challenge, requiring intricate structural engineering to optimize electron transfer during the oxygen reduction reaction (ORR). Herein, we introduce a novel design of covalent organic frameworks (COFs) that effectively shift the ORR from a four‐electron to a more advantageous two‐electron pathway. Notably, the JUC‐660 COF, with strategically charge‐modified benzyl moieties, achieved a continuous high H2O2 yield of over 1200 mmol g−1 h−1 for an impressive duration of over 85 hours in a flow cell setting, marking it as one of the most efficient metal‐free and non‐pyrolyzed H2O2 electrocatalysts reported to date. Theoretical computations alongside in situ infrared spectroscopy indicate that JUC‐660 markedly diminishes the adsorption of the OOH* intermediate, thereby steering the ORR towards the desired pathway. Furthermore, the versatility of JUC‐660 was demonstrated through its application in the electro‐Fenton reaction, where it efficiently and rapidly removed aqueous contaminants. This work delineates a pioneering approach to altering the ORR pathway, ultimately paving the way for the development of highly effective metal‐free H2O2 electrocatalysts.
Nanoarchitectonics of S‐Scheme Heterojunction Photocatalysts: A Nanohouse Design Improves Photocatalytic Nitrate Reduction to Ammonia Performance
Authors: Xi Yamin , Xiang Yitong , Bao Tong , Li Zhijie , Zhang Chaoqi , Yuan Ling , Li Jiaxin , Bi Yin , Yu Chengzhong , Liu Chao 
Published: June 2024

AbstractPhotocatalytic nitrate reduction reaction (NitRR) is a promising route for environment remediation and sustainable ammonia synthesis. To design efficient photocatalysts, the recently emerged nanoarchitectonics approach holds great promise. Here, we report a nanohouse‐like S‐scheme heterjunction photocatalyst with high photocatalytic NitRR performance. The nano‐house has a floor of plate‐like metal organic framework‐based photocatalyst (NH2‐MIL‐125), on which another photocatalyst Co(OH)2 nanosheet is grown while ZIF‐8 hollow cages are also constructed as the surrounding wall/roof. Experimental and simulation results indicate that the positively charged, highly porous and hydrophobic ZIF‐8 wall can modulate the environment in the nanohouse by (i) NO3− enrichment/NH4+ discharge and (ii) suppression of the competitive hydrogen evolution reaction. In combination with the enhanced electron‐hole separation and strong redox capability in the NH2‐MIL‐125@Co(OH)2 S‐scheme heterjunction confined in the nano‐house, the designed photocatalyst delivers an ammonia yield of 2454.9 μmol g−1 h−1 and an apparent quantum yield of 8.02 % at 400 nm in pure water. Our work provides new insights into the design principles of advanced photocatalytic NitRR photocatalyst.
Lattice Oxygen in Photocatalytic Gas–Solid Reactions: Participator vs. Dominator
Authors: Li Zhonghua , Chen Ping , Feng Jianyong , Zhao Minyue , Zhao Zongyan , Zhang Yuanming , Xu Xiaoming , Huang Huiting , Zou Zhigang , Li Zhaosheng 
Published: June 2024

AbstractLattice‐oxygen activation has emerged as a popular strategy for optimizing the performance and selectivity of oxide‐based thermocatalysis and electrolysis. However, the significance of lattice oxygen in oxide photocatalysts has been ignored, particularly in gas–solid reactions. Here, using methane oxidation over a Ru1@ZnO single‐atom photocatalyst as the prototypical reaction and via 18O isotope labelling techniques, we found that lattice oxygen can directly participate in gas–solid reactions. Lattice oxygen played a dominant role in the photocatalytic reaction, as determined by estimating the kinetic constants in the initial stage. Furthermore, we discovered that dynamic diffusion between O2 and lattice oxygen proceeded even in the absence of targeted reactants. Finally, single‐atom Ru can facilitate the activation of adsorbed O2 and the subsequent regeneration of consumed lattice oxygen, thus ensuring high catalyst activity and stability. The results provide guidance for next‐generation oxide photocatalysts with improved activities and selectivities.
Guidelines in Practice: Team Communication
Authors: Speth Jennifer 
Published: June 2024

ABSTRACTThe perioperative setting is a complex environment requiring interdisciplinary team collaboration to avoid adverse events. To protect the safety of patients and perioperative team members, communication among personnel should be clear and effective. The recently updated AORN “Guideline for team communication” provides perioperative nurses with recommendations on the topic. To promote effective communication in perioperative areas, all personnel should value and commit to a culture of safety. This article discusses recommendations for supporting a culture of safety, developing and implementing an effective hand‐off process and surgical safety checklist, and developing education strategies for team communication. It also includes a scenario describing the implementation of a standardized, electronic surgical safety checklist in the OR. Perioperative nurses should review the guideline in its entirety and apply the recommendations for team communication in their working environments.
Improving Intraoperative Parathyroid Hormone Specimen Handling and Processing
Authors: Murgatroyd Jocelyn , Wagner Laura M. , Duh Quan‐Yang 
Published: June 2024

ABSTRACTSurgeons request intraoperative parathyroid hormone (PTH) monitoring during parathyroidectomy procedures to confirm identification of abnormal gland tissue. Generally, a 50% decrease in the baseline PTH level indicates the abnormal tissue has been removed. A delay in collecting and processing PTH blood samples can complicate intraoperative decision making and prolong the procedure. The purpose of this quality improvement project was to develop tools to facilitate the specimen management process (eg, requesting, transporting, analyzing) for PTH blood samples and decrease the average total time required for transit and assay. We implemented a two‐pronged initiative that involved improving the laboratory requisition form and creating a parathyroid tote box to contain all the needed information and supplies. The average total time for transit and assay decreased from 31.36 minutes before implementation to 22.06 minutes after implementation. Perioperative nurses expressed satisfaction with the changes and continue to use the revised process.
Enhancement of CO2 separation efficiency in mixed matrix membranes through zinc ion modified g‐C3N4 nanosheets
Authors: Sun Qin‐Qin , Zhu Ming‐Chao , Zhu Peng‐fei , OuYang Yun‐Xiang , Lu Yong‐Ze , Li Na , Chen Shou‐Wen 
Published: June 2024

AbstractThis study employed modified graphitic carbon nitride (g‐C3N4) nanosheets and polyether block amide (Pebax) to prepare mixed matrix membranes (MMMs) aiming to enhance CO2 separation efficiency. Through sulfonation and zinc ion (Zn2+) modification of g‐C3N4 nanosheets, high Zn2+ loaded nanofillers (SCN‐Zn2+) were synthesized. Compared to g‐C3N4, MMMs with SCN‐Zn2+ as nanofiller showed a CO2 permeance of 462 Barrer as well as the CO2/N2 selectivity of 47.5 at the feed gas pressure of 2 bar, which surpassed the 2008 Robeson upper bound. Additionally, the Pebax/SCN‐Zn2+(30) membrane was subjected to continuous gas permeability experiments for 70 h and showed good stability. The results showed that SCN‐Zn2+ nanosheets played an important role in enhancing the gas selectivity of the membranes. SEM confirmed that the SCN‐Zn2+ nanosheets had good compatibility with the Pebax substrate and the presence of hydrophilic sulfonic acid groups effectively suppressed the interfacial defects. The increase in the free volume fraction of the membranes as well as the solubility and diffusion coefficient suggested that the introduction of g‐C3N4 nanosheets led to more tortuous gas transport paths, which enhanced the permeability and selectivity of CO2.
Optimizing Electrodeposition of Polyaniline on Various Woven Steel Mesh Sizes for Enhanced Supercapacitor Performance
Authors: Abbas Dalhatu Ahmad , Faisal Al‐Betar Abdul‐Rahman , Dahiru Abubakar , Shaheen Shah Syed , Abdul Aziz Md. 
Published: June 2024

AbstractThe development of efficient supercapacitors hinges on the innovation of superior electrodes, which are pivotal in augmenting their energy storage capabilities. Supercapacitors, recognized for their high‐power density and extended cycle life, play a crucial role as sustainable solutions in addressing energy storage challenges. A fundamental aspect of supercapacitor functionality involves the electrode material, which works in concert with other key components such as the current collector, separator, and electrolyte. This study focuses on evaluating the impact of the current collector material on the performance of symmetric supercapacitors. We investigated the electropolymerization of polyaniline on woven steel mesh current collectors of varying mesh sizes, ranging from 20 to 200 mesh per inch, using assorted deposition conditions. The electrochemically modified woven steel meshes were utilized to construct symmetric supercapacitors. The electrochemical performance of the assembled supercapacitors, configured in a two‐electrode system, was investigated using a variety of electrochemical techniques to better understand the kinetics of electrolyte ion migration. Notably, the 20‐mesh size, characterized by the fewest pores per inch, demonstrated superior performance with an optimum capacitance of 4730 mF/cm2, an energy density of 317.8 μWh/cm2, and a power density of 400 μW/cm2 at a current density of 1 mA/cm2.
Impact of green human resource management and internal green supply chain management practices on operational performance: An empirical investigation of manufacturing sector
Authors: Gelagay Daniel Atnafu , Werke Shimelis Zewdie 
Published: June 2024

AbstractThe increasing environmental impact has triggered a global shift towards eco‐friendly business strategies. This study examines the impact of green human resource management (GHRM) and internal green supply chain management (IGSCM) on operational performance within the Ethiopian manufacturing sector. Survey data from 219 large and medium‐sized companies in the leather, textiles, agro processing, and cement industries were analysed using partial least squares structural equation modelling. The findings demonstrate that IGSCM practises, such as eco‐design and internal environmental management, have a positive impact on operational performance. GHRM encourages a culture that supports these practises. Mediation analysis reveals that GHRM indirectly enhances operational performance through IGSCM practises. This study contributes to the existing literature on sustainable HR and supply chain management by emphasising the importance of integrating environmental considerations into HR and supply chain strategies to enhance operational outcomes. Policymakers are encouraged to utilise these findings to develop frameworks that promote environmentally sustainable business practises.
Working title: Molecular involvement of p53‐MDM2 interactome in gastrointestinal cancers
Authors: Yedla Poornachandra , Bhamidipati Pranav , Syed Riyaz , Amanchy Ramars 
Published: June 2024

AbstractThe interaction between murine double minute 2 (MDM2) and p53, marked by transcriptional induction and feedback inhibition, orchestrates a functional loop dictating cellular fate. The functional loop comprising p53‐MDM2 axis is made up of an interactome consisting of approximately 81 proteins, which are spatio‐temporally regulated and involved in DNA repair mechanisms. Biochemical and genetic alterations of the interactome result in dysregulation of the p53‐mdm2 axis that leads to gastrointestinal (GI) cancers. A large subset of interactome is well known and it consists of proteins that either stabilize p53 or MDM2 and proteins that target the p53‐MDM2 complex for ubiquitin‐mediated destruction. Upstream signaling events brought about by growth factors and chemical messengers invoke a wide variety of posttranslational modifications in p53‐MDM2 axis. Biochemical changes in the transactivation domain of p53 impact the energy landscape, induce conformational switching, alter interaction potential and could change solubility of p53 to redefine its co‐localization, translocation and activity. A diverse set of chemical compounds mimic physiological effectors and simulate biochemical modifications of the p53‐MDM2 interactome. p53‐MDM2 interactome plays a crucial role in DNA damage and repair process. Genetic aberrations in the interactome, have resulted in cancers of GI tract (pancreas, liver, colorectal, gastric, biliary, and esophageal). We present in this article a review of the overall changes in the p53‐MDM2 interactors and the effectors that form an epicenter for the development of next‐generation molecules for understanding and targeting GI cancers.
A Bispecific Chimeric Aptamer Design Platform Based on c‐MET Aptamer with a Replaceable Redundant Region
Authors: Zhang Xiangru , Zhang Nan , Sun Haojun , Li Dandan , Long Zhenhao , Sheng Jing , Zu Shuang , Bing Tao , Shangguan Dihua 
Published: June 2024

AbstractMolecular engineering enables the creation of aptamers with novel functions, but the prerequisite is a deep understanding of their structure and recognition mechanism. The cellular‐mesenchymal epithelial transition factor (c‐MET) is garnering significant attention due to the critical role of the c‐MET/HGF signaling pathway in tumor development and invasion. This study reports a strategy for constructing novel chimeric aptamers that bind to both c‐MET and other specific proteins. c‐MET was identified to be the molecular target of a DNA aptamer, HF3‐58, selected through cell‐SELEX. The binding structure and mechanism of HF3‐58 with c‐MET were systematically studied, revealing the scaffold, recognition, and redundancy regions. Through molecular engineering design, the redundancy region was replaced with other aptamers possessing stem‐loop structures, yielding novel chimeric aptamers with bispecificity for binding to c‐MET and specific proteins. A chimeric bispecific aptamer HF‐3b showed the ability to mediate the adhesion of T‐cells to tumor cells, suggesting the prospective utility in tumor immunotherapy. These findings suggest that aptamer HF3‐58 can serve as a molecular engineering platform for the development of diverse multifunctional ligands targeting c‐MET. Moreover, comprehensive understanding of the binding mechanisms of aptamers will provide guidance for the design of functional aptamers, significantly expanding their potential applications.
(S)‐ML‐SA1 Activates Autophagy via TRPML1‐TFEB Pathway
Authors: Cunha Micael R. , Do Amaral Bruno S. , Takarada Jéssica E. , Valderrama Gabriel V. , Batista Andrea N. L. , Batista João M. , Cass Quezia B. , Couñago Rafael M. , Massirer Katlin B. 
Published: June 2024

AbstractAutophagic flux plays a crucial role in various diseases. Recently, the lysosomal ion channel TRPML1 has emerged as a promising target in lysosomal storage diseases, such as mucolipidosis. The discovery of mucolipin synthetic agonist‐1 (ML‐SA1) has expanded our understanding of TRPML1′s function and its potential therapeutic uses. However, ML‐SA1 is a racemate with limited cellular potency and poor water solubility. In this study, we synthetized rac‐ML‐SA1, separated the enantiomers by chiral liquid chromatography and determined their absolute configuration by vibrational circular dichroism (VCD). In addition, we focused on investigating the impact of each enantiomer of ML‐SA1 on the TRPML1‐TFEB axis. Our findings revealed that (S)‐ML‐SA1 acts as an agonist for TRPML1 at the lysosomal membrane. This activation prompts transcription factor EB (TFEB) to translocate from the cytosol to the nucleus in a dose‐dependent manner within live cells. Consequently, this signaling pathway enhances the expression of coordinated lysosomal expression and regulation (CLEAR) genes and activates autophagic flux. Our study presents evidence for the potential use of (S)‐ML‐SA1 in the development of new therapies for lysosomal storage diseases that target TRPML1.
Ultrafine Ru Nanoparticles Supported on Mesoporous Silica for Hydrogen Production via Decomposition of Ammonia
Authors: Tang Shu , Ding Jun , Li Wenyi , Zhang Shengbo , Zhang Haimin 
Published: June 2024

AbstractWe reported metallic ruthenium (Ru) nanoparticles loaded on amino modified dendritic mesoporous silica microspheres (Ru/NH2‐DMSMs) for ammonia decomposition to hydrogen. The sizes of the loaded Ru nanoparticles on carrier are 2–3 nm, providing rich active sites for ammonia decomposition reaction. As a result, the obtained Ru/NH2‐DMSMs‐5.1 can afford almost ~100 % ammonia decomposition at 550 °C, due to the unique mesoporous structure of DMSMs inhibiting the aggregation of active Ru nanoparticles and enhancing the mass transport of ammonia.
Study of Mass Transport in the Anode of a Proton Exchange Membrane Fuel Cell with a New Hydrogen Flow‐Rate Modulation Technique
Authors: Duque Luis , Molinero Antonio , Oller J. Carlos , Barcala J. Miguel , Diaz‐Alvarez E. , Folgado M. Antonia , Chaparro Antonio M. 
Published: June 2024

AbstractHydrogen transport in the anode of a proton‐exchange membrane fuel cell (PEMFC) has been studied with a modulation technique relating the hydrogen flow‐rate (
) and the faradaic current (
), called Current‐modulated Hydrogen flow‐rate Spectroscopy (CH2S). A simple analytical expression for the transfer function, H(jω)=n F
/
, is provided, showing a skewed semicircle in Nyquist representation (−H'' vs. H'), extending from H’=0 to H’=1, and with the maximum frequency at ωmax=2.33(DH2 /Li2), where DH2 is the effective hydrogen diffusivity and Li the thickness of the anode gas diffusion layer (GDL). The expression for CH2S is also calculated with an existing reversible chemical reaction in the GDL. Experimental results under different operation conditions show two transport processes limiting the anode reaction, one attributed to molecular diffusion through the partially saturated GDL, and the other to the microporous layer (MPL), or its interfaces with GDL or with the catalyst layer (CL). CH2S provides the hydrogen diffusivities (DH2,i) associated to each process under the different conditions. Current density decreases slightly the diffusivity of the GDL, while it becomes activated in the MPL; using two GDLs in the anode improves both GDL and MPL diffusivities; humidification decreases the diffusivity in both, GDL and MPL; finally, a superhydrophobic anodic CL prepared by electrospray improves hydrogen diffusivity in GDL and MPL.
A semi‐automated and structured approach for creating a Geotechnical Synthesis Model
Authors: Werkgarner Hannah , Salzgeber Hannah , Exenberger Hans , Harder Manfred , Schneiderbauer Larissa 
Published: June 2024

AbstractThis article presents an innovative approach to structured information exchange in ground modeling, integrating geology, geotechnics, and hydrogeology. It proposes a data framework seamlessly merging the DAUB's modeling guidelines with the University of Innsbruck research. Addressing diverse data management challenges and ensuring interoperability, the workflow offers solutions for CAD‐ and interpolation‐based modeling, enabling semi‐automated generation of Geotechnical Synthesis Models with open file format export. Overcoming obstacles, the article introduces a uniform rasterization method, defining a tunnel‐specific repository voxel (Tuxel). Results showcase a streamlined, semi‐automated process using Autodesk Civil 3D® and Seequent Leapfrog Works®, enhancing data uniformity and enabling cross‐project information exchange. This workflow provides practical solutions for collaborative ground modeling within BIM/TIM frameworks, fostering efficient and standardized data handling.
Probing Basal and Prismatic Planes of Graphitic Materials for Metal Single Atom and Subnanometer Cluster Stabilization
Authors: Vidal Mathieu , Pandey Jyoti , Navarro‐Ruiz Javier , Langlois Joris , Tison Yann , Yoshii Takeharu , Wakabayashi Keigo , Nishihara Hirotomo , Frenkel Anatoly I. , Stavitski Eli , Urrutigoïty Martine , Campos Cristian H. , Godard Cyril , Placke Tobias , del Rosal Iker , Gerber Iann C. , Petkov Valeri , Serp Philippe 
Published: June 2024

AbstractSupported metal single atom catalysis is a dynamic research area in catalysis science combining the advantages of homogeneous and heterogeneous catalysis. Understanding the interactions between metal single atoms and the support constitutes a challenge facing the development of such catalysts, since these interactions are essential in optimizing the catalytic performance. For conventional carbon supports, two types of surfaces can contribute to single atom stabilization: the basal planes and the prismatic surface; both of which can be decorated by defects and surface oxygen groups. To date, most studies on carbon‐supported single atom catalysts focused on nitrogen‐doped carbons, which, unlike classic carbon materials, have a fairly well‐defined chemical environment. Herein we report the synthesis, characterization and modeling of rhodium single atom catalysts supported on carbon materials presenting distinct concentrations of surface oxygen groups and basal/prismatic surface area. The influence of these parameters on the speciation of the Rh species, their coordination and ultimately on their catalytic performance in hydrogenation and hydroformylation reactions is analyzed. The results obtained show that catalysis itself is an interesting tool for the fine characterization of these materials, for which the detection of small quantities of metal clusters remains a challenge, even when combining several cutting‐edge analytical methods.