bluuebunny/crossref_metadata_2025_split huggingface dataset:
Risk of adverse cardiovascular events based on common genetic variants in 8-year follow-up of the LIPIDOGEN2015 population using the polygenic risk score (PRS) - study design and methodology.
Authors: Banach Maciej , Fronczek Martyna , Osadnik Tadeusz , Gach Agnieszka , Strapagiel Dominik , Słomka Marcin , Lejawa Mateusz , Goc Anna , Boniewska-Bernacka Ewa , Pańczyszyn Anna , Lip Gregory Y.H. , Toth Peter P. , Penson Peter E. , Jóźwiak Jacek 
Published: August 2024

IntroductionClassical risk factors such as hypertension, hypercholesterolemia, pre-diabetes, diabetes and obesity can predict adverse cardiovascular events, but they are less prognostic in patients age <60 years. Polygenic risk scores (PRS) can be effective in predicting adverse coronary events in younger and middle-aged patients. Our main aim is to assess the utility of new PRS created for the Polish population in predicting mortality during an 8-year follow-up in a nationwide LIPIDOGEN2015 population.Material and methodsAll DNA samples of 1779 patients were genotyped using Infinium Global Screening Array-24+ v3.0 Kit microarrays. The samples were amplified, fragmented, and hybridized to BeadChips. The BeadChips were scanned using iScan and converted to genotypes using Genome Studio 2.0.ResultsWe will develop a PRS based on the marked single nucleotide polymorphisms (SNPs) in the LIPIDOGEN2015 project's studied population and determine the analyzed group's risk of death due to cardiovascular diseases (CVD) based on data obtained from 8-years of patient-follow-up. Based on the developed PRS scale and biochemical analyses, we will assess the effectiveness of lipid-lowering therapy with statins in patients with high and low genetic risk of sudden CVD events (secondary endpoints).ConclusionsThe developed PRS scale, combined with clinical covariates, will facilitate the creation of an algorithm to predict long-term mortality. This will enable us to stratify CVD risk more precisely, which may result in earlier implementation of lifestyle changes and dietary adjustments and potentially initiate earlier pharmacotherapy for at-risk individuals.
THỰC TRẠNG CHĂM SÓC DẪN LƯU BÀNG QUANG TRÊN NGƯỜI BỆNH SAU PHẪU THUẬT NỘI SOI TĂNG SẢN LÀNH TÍNH TUYẾN TIỀN LIỆT TẠI BỆNH VIỆN ĐA KHOA TỈNH NINH BÌNH NĂM 2022
Authors: Phạm Thị Nga 
Published: August 2024

Nghiên cứu được thực hiện nhằm mô tả thực trạng và xác định một số yếu tố liên quan đến chăm sóc dẫn lưu bàng quang trên người bệnh sau phẫu thuật nội soi tăng sản lành tính tuyến tiền liệt tại bệnh viện đa khoa tỉnh Ninh Bình. Kết quả của nghiên cứu cho thấy rằng: Thực hiện chăm sóc đạt ở mức khá cao, với thực hiện về y lệnh chiếm 100% và nhận định người bệnh ở mức 92,9%, thực hiện chăm sóc thấp nhất là phần giáo dục sức khỏe cho người bệnh, với phần tư vấn về chế độ dinh dưỡng chỉ ở mức 28,6%. Trình độ chuyên môn, kiến thức của người điều dưỡng về chăm sóc người bệnh sau phẫu thuật tăng sản lành tính tuyến tiền liệt, rào cản có mối tương quan tới thực hiện chăm sóc. Trong đó trình độ chuyên môn có mối tương quan thuận và lớn nhất với r = 0,78, p < 0,01 và rào cản có mối tương quan nghịch với r = -0,77, p < 0,01. Tuổi và số năm công tác không có mối liên quan đến thực hiện kỹ thuật chăm sóc.
Risk-informed representative earthquake scenarios for Valparaíso and Viña del Mar, Chile
Authors: Rosero-Velásquez Hugo , Monsalve Mauricio , Gómez Zapata Juan Camilo , Ferrario Elisa , Poulos Alan , de la Llera Juan Carlos , Straub Daniel 
Published: August 2024

Abstract. Different risk management activities, such as land-use planning, preparedness, and emergency response, utilize scenarios of earthquake events. A systematic selection of such scenarios should aim at finding those that are representative of a certain severity, which can be measured by consequences to the exposed assets. For this reason, defining a representative scenario as the most likely one leading to a loss with a specific return period, e.g., the 100-year loss, has been proposed. We adopt this definition and develop enhanced algorithms for determining such scenarios for multiple return periods. With this approach, we identify representative earthquake scenarios for the return periods of 50, 100, 500, and 1000 years in the Chilean communes of Valparaíso and Viña del Mar, based on a synthetic earthquake catalog of 20 000 scenarios on the subduction zone with a magnitude of Mw≥5.0. We separately consider the residential-building stock and the electrical-power network and identify and compare earthquake scenarios that are representative of these systems. Because the representative earthquake scenarios are defined in terms of the annual loss exceedance rates, they vary in function of the exposed system. The identified representative scenarios for the building stock have epicenters located not further than 30 km from the two communes, with magnitudes ranging between 6.0 and 7.0. The epicenter locations of the earthquake scenarios representative of the electrical-power network are more spread out but not further than 100 km away from the two communes, with magnitudes ranging between 7.0 and 9.0. For risk management activities, we recommend considering the identified scenarios together with historical events.
Sulfide Mineralization and Associated Platinum Group Elements in Mafic-Ultramafic Units of the Tantalite Valley Complex, Southern Namibia
Authors: Ferreira D. R. , Von der Heyden B. P. , Klausen M. , Martin L. 
Published: August 2024

Abstract
The formation of an immiscible sulfide melt, with associated base, semiprecious, and precious metals, is an important ore-forming process in mafic-ultramafic systems. These magmatic deposits are of great economic importance because they are our primary source of global platinum group element (PGE) reserves—metals that will play a crucial role in facilitating the green energy transition. This study focuses on the Tantalite Valley Complex in southern Namibia and the formation of sulfides within mafic-ultramafic layers, as well as their potential to host valuable metals (PGEs + Ni-Cu-Co). The study investigates the source of sulfur, the fractionation of precious metals between sulfide phases including subsequent alteration assemblages, and the textures and distribution of these minerals, as well as approximating the R factor of the system to assess the mineralization potential of the complex. In situ sulfur isotope and S/Se studies suggest that the origin of the sulfur in the system was derived from the mantle. Sulfide saturation likely occurred because of high degrees of crystal fractionation, and the resultant immiscible sulfide melt percolated into the ultramafic layers (notably an orthopyroxenite layer), accumulating in the basal parts of the magma chamber. Noble metals exist in both solid solution and discrete precious metal-bearing minerals found closely associated with sulfide phases. The R factor for the complex stands at approximately 3,000, which suggests that a small fraction of sulfide melt formed and mixed at moderate to high degrees with the silicate magma. This study provides the first indication of PGE occurrence, and thus further prospectivity, in a poorly explored mafic magmatic suite located in the underexplored geologic terrane (i.e., the Gordonia subprovince of the Namaqua Natal metamorphic province).
Normativity Naturalized? Some Thoughts on Bruno Celanos Pre-Conventions
Authors: Escher Ana 
Published: August 2024

Bruno Celanos thought-provoking 2016 paper on Pre Conventions, A fragment of the Background prompted intense discussion. Unsurprisingly so given the perplexity as to the existence of entities which dwell both in the normative and the factual realms. Ever since Hume and Moore we have grown zealous about this divide. My aim here, however, is neither an in-debt discussion of Humes Law nor a detailed critical analysis of Celanos Pre Conventions. Rather, I want to point out that the underlaying structure of Celanos Pre Conventions closely resembles theoretical constructs offered by linguistic philosophers (and interestingly so, of the externalist branch) in their meaning formation explanations. I am thinking in particular of Millikans construct of natural conventions, reproduction and precedent. Following this thread, the question of the normativity of Celanos embodied facts seems to mirror the disjunction problem in informational theories of meaning (Fodor) and the general question of normativity of meaning (correctness conditions of terms implying meaning normativity). What I have in mind here is, then, to assess the validity and reach of Celanos claim not about the existence of entities of this type, but about their inherent normative nature.
QUANTIFICATION OF THROMBUS BURDEN AND IDENTIFICATION OF ITS DETERMINANTS IN PATIENTS OF ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION UNDERGOING PRIMARY PERCUTANEOUS INTERVENTION
Authors: KHAN AR , AQEEL M , AHMAD R , HAMID S , ARSHAD A , ZAHOOR S 
Published: August 2024

Primary PCI is the gold standard treatment of STEMI. Thrombus Burden in coronary vessels is the main challenge for a good procedure prognosis. We aimed to analyze thrombus burden and to identify its determinants. Objective: To evaluate the extent of thrombus burden in coronary vessels and identify associated determinants in patients treated with primary PCI. Methods: A single center cross-sectional survey that included 470 patients was conducted at the Punjab Institute of Cardiology, Lahore from June 2023 to December 2023. We recorded demographics and risk factors in history. The angiographic findings about thrombus burden and TIMI flow were recorded before and after the procedure. All the collected data was analyzed using SPSS 23.00. Results: The mean age of the participants was 51.97±10.84 years. 410 (87.2%) were male patients and 60(12.8%) females were included in this study. 283 (60.2%) patients in our study had a high thrombus burden, whereas 187 (39.8%) patients had a low thrombus burden. There was a significant difference in TIMI flow before and after the procedure (p-value = 0.004). Four patients had no flow. All of them had high thrombus burden but were not found to be associated significantly (p-value>0.05). Conclusion: Most of the patients with STEMI had a high thrombus burden. Risk factors of IHD were not associated with high thrombus burden. 410 (87.2%) were male patients and 60(12.8%) females were included in this study.
Pengaruh Profitabilitas, Ukuran Perusahaan, dan Leverage Terhadap Penghindaran Pajak Pada Perusahaan Pertambangan yang Terdaftar di BEI
Authors: Puja Raihani Puja Raihani , Muhammad Salman  , Tuti Meutia  
Published: August 2024

This research aims to examine the effect of: (1) profitability on tax avoidance, (2) firm size on tax avoidance, (3) leverage on tax avoidance, (4) profitability, company size and leverage on tax avoidance simultaneously. This research is a quantitative research with the population in this research being 87 energy sector mining companies listed on the IDX, and a sample of 8 companies. The data analysis technique in this research uses descriptive statistical tests, classical assumption tests, t tests, simultaneous tests and determination tests (R2). The results of the t test for the profitability variable have a value of 0,004<0,05, which means that the profitability variable has a significant influence on tax avoidance. The company size variable has a value of 0,000<0,05 which means that the company size variable has a significant influence on tax avoidance. The leverage variable has a value of 0.771 > 0.05, which means that the leverage variable does not have a significant influence on tax avoidance. The results of the F test obtained a value of 0.000 < 0.05, indicating that the variables used in this research simultaneously have a significant effect on tax avoidance. From the results of the coefficient of determination test, it was found that 30,3% of the dependent variable could be explained by the independent variable, while the remaining 69,7% was influenced by other factors not included in this research.
Epidemia de Dengue: uma análise sobre as projeções para o ano de 2024
Authors: Dias Grazielle Maria Coutinho , Machado Brenna Kurt Reis de Morais Rezende Dante , Sousa Mariana Lobo Mendonça de , Alves Felipe Silvério , Mello Vitória Moreira de , Ferreira Sophia Maia , Silva Rosana de Sousa da , Castro Taline Monteiro Barros de , Oliveira Maria Eduarda Dornelles de , Melo Gabrielle Nascimento de , Melo Sarah Nascimento de , Farias Ireni da Silva , Fiedler Emmanuele 
Published: August 2024

A dengue é uma doença sistêmica, febril aguda e dinâmica que varia de casos assintomáticos a doenças graves e até a morte. No Brasil, o vírus da dengue é transmitido pelas fêmeas do mosquito Aedes aegypti (Leite et al., 2020). Estatísticas mostram que este ano o Brasil enfrentará o pior surto de dengue dos últimos anos. Dito isso, o estudo tem como objetivo realizar uma análise sobre a epidemia de dengue em 2024 no Brasil no estado de Goiás com base nos últimos anos, e apresentar as ações adotadas pelo governo para mitigar esse problema. O estudo trata-se de um estudo descritivo de casos confirmados na região de Goiás notificados no sistema. Os dados nos sites do Ministério da Saúde e Secretaria do Estado de Goiás e demais fontes seguras indicaram que em 2024 o Brasil registrou mais de 1 milhão de casos de dengue e cerca de 214 mortes pela doença. Dados indicaram que no mesmo período de 2023 o país apresentou um número bem distinto de casos e óbitos, com 207.475 e 149, respectivamente. Devido a incidência de casos o país já declarou estado de alerta e diversos Estados brasileiros estão adotando medidas de combate à transmissão e proliferação do mosquito. Entretanto, embora o Governo Nacional e dos Estados estejam atuando fortemente para essa causa, a população possui responsabilidade ativa na mitigação do vírus, o que torna a necessidade de conscientização ainda mais evidente.
The Influence of Organizational Support and Turn of Duty on Performance Through Work Engagement in the Surabaya Transportation Department
Authors: Arifianti Erny Lutfiyah , Fauzi Akhmad , Swasti Ika Korika 
Published: August 2024

This research aims to examine the effect of organizational support and turn of duty on employee performance through work engagement at the Surabaya City Transportation Agency. This study uses a quantitative approach and survey technique involving Civil Servants at the Surabaya City Transportation Agency as respondents. Data was collected through questionnaires distributed to employees. Data analysis was performed using statistical techniques to test the relationships between the variables studied. The sample of this study consists of 76 staff-level employees from various work units and educational levels. The data from the sample were analyzed using Structural Equation Modelling (SEM) based on partial least squares (SEM-PLS). The findings indicate that: 1) organizational support has a non-significant effect on performance; 2) turn of duty has a non-significant effect on performance; and 3) organizational support has a significant effect on performance through work engagement; 4) turn of duty has a significant effect on performance through work engagement. This indicates that although employee engagement at the workplace increases both through organizational support and turn of duty, it does not directly or indirectly enhance employee performance. Work engagement acts as a crucial mediator where employees who feel engaged with their work tend to have a better understanding of their duties and responsibilities and are intrinsically motivated to work responsibly.
Political Communication Strategy and Public Opinion for the Victory of the Prabowo Gibran Pair in the 2024 Presidential and Vice Presidential Elections of the Republic of Indonesia
Authors: Fardiansyah Hardi , Euis Komalawati  
Published: August 2024

In the context of a political communication strategy focused on the campaign for candidate pair number 2 Prabowo Subianto-Gibran Rakabuming Raka, this research shows that their communication strategy is very effective, especially among young voters. This research uses a qualitative approach with primary data in the form of interviews and documentation from various informants, such as TKN/Golkar/Partai Pengusung, TKN Secretary, as well as the community and volunteers who were randomly selected. The research results show the Prabowo-Gibran communication strategy. First, the Prabowo-Gibran candidate pair aims to convince the public, especially Generation Z, about their vision and mission as presidential candidates. This goal includes efforts to build a positive image, increase electability, and win the presidential election. Second, these candidate pairs use various persuasive communication strategies, such as creative and diverse campaigns, the use of social media to spread messages, and participation in debates to strengthen their arguments and vision. Third, the Prabowo-Gibran candidate pair targets Generation Z in particular as important potential voters, using language and communication platforms that suit Generation Z's preferences and habits to increase their appeal
Komposisi Botani dan Kapasitas Tampung Area Penggembalaan pada Perkebunan Kelapa di Desa Labelete Kecamatan Kulisusu Utara Kabupaten Buton Utara
Authors: Hasrifa  , Sandiah Natsir , Kurniawan Widhi 
Published: August 2024

Penelitian bertujuan untuk mengevaluasi komposisi botani dan kapasitas tamping aere penggembalaan pada perkebunan kelapa di Desa Labelete Kecamatan Kulisusu Utara Kabupaten Buton Utara. Metode yang digunakan pada penelitian adalah metode survei dan pengukuran serta pengamatan secara langsung di lapangan. Pengukuran produksi hijauan menggunakan metode “Actual Weight Estimate” dengan menggunakan kuadran berukuran 1meter × 1 meter. Data yang diperoleh ditabulasi dan dianalisis menggunakan metode deskriptif. Hasil penelitian menunjukan bahwa area penggembalaan pada perkebunan kelapa di Desa Labelete memiliki presentasi rumput 56,11%, leguminosa 18,43% dan gulma 25,46%. Kapasitas tampung area penggembalaan pada perkebunan kelapa di Desa Labelete yakni 0.59 ST/ha/tahun dengan produksi hijauan segar berupa rumput 1.430 kg/ha, leguminosa 303,62 dan gulma 432,5 kg/ha.
Konsumsi Energi, Energi Tercerna Dan Energi Metabolisme Dari Kambing Kacang Jantan Yang Dipelihara Secara Intensif Di musim Kemarau
Authors: Nahak Meliana , Tahuk Paulus Klau , Nahak Oktovianus R. 
Published: August 2024

Penelitian ini bertujuan untuk mengetahui Konsumsi Energi, Energi Tercerna Dan Energi Metabolisme Dari Kambing Kacang Jantan Yang Dipelihara Secara Intensif Di Musim Kemarau. Penelitian ini dilaksanakan di kandang percobaan Fakultas Pertanian, Sains Dan Kesehatan, Universitas Timor, Kabupaten Timor Tengah Utara (TTU). Penelitian ini dilaksanan dari bulan Juli - September 2023. Kambing Kacang jantan yang digunakan sebanyak 9 ekor. penelitian ini menggunakan Rancangan Acak Lengkap (RAL) yang terdiri dari 3 perlakuan dan 3 ulangan. perlakuan yang diberikan adalah T1: Ternak memperoleh level energi 65%,+PK:15%, T2 : Ternak memperoleh level energi 67%,+PK:15%, T3 Ternak memperoleh level energi 70%,+PK:15%. Variabel yang diamati dalam penelitian ini adalah konsumsi energi, energi metabolisme, dan energi tercerna. Data yang diperoleh dianalisis dengan sidik ragam (ANOVA) dan Uji Jarak Berganda Duncan. Hasil penelitian menunjukkan bahwa rata-rata konsumsi energi pada perlakuan T1 T2, T3 masing-masing adalah T1 sebesar, 1190,89±63,02 T2 sebesar 1467,14±60,56 dan T3 sebesar 1364,03±143,25 (Kkal/Kg.Bk/Hari) energi metabolisme T1 sebesar 523,99±54,68 T2 sebesar 764,33±52,68 dan T3 sebesar 674,63±124,63 (Kkal/Kg.Bk/Hari) Energi tercerna T1 sebesar 651,86±63,02, T2 sebesar 928,11±60,56 dan T2 sebesar 825,00±143,26 (Kkal/Kg.Bk/Hari). Hasil penelitian menunjukkan bahwa perlakuan berpengaruh nyata terhadap konsumsi energi, energi metabolisme dan energi tercerna (P<0,05). Disimpulkan bahwa penggunaan level energi 67 -70% dalam ransum dapat meningkatkan konsumsi energi, energi tercerna, dan energi metabolis, menurunkan ekskresi energi feses. Sebaliknya, peningkatan energi ransum berkontribusi pada meningkatnya ekskresi energi melalui urin dan gas methan.
Analisis Potensi Energi Angin Menggunakan Turbin Horizontal di Kawasan Wisata Mangrove Desa Tanjung Rejo, Kecamatan Percut Sei Tuan
Authors: Idris Muhammad , Zulfikar Achmad Jusuf , Darianto Darianto , Iswandi Iswandi , Jufrizal Jufrizal , Hermanto Tino , Haniza Haniza , Harahap Uun Novalia 
Published: August 2024

Tridarma perguruan tinggi merupakan tugas pokok dan fungsi bagi setiap dosen yang harus dilaksanakan setiap semester. Salah satu kegiatan tridarma perguruan tinggi ialah pengabdian kepada masayarakat yang bertujuan untuk meberikan kontribusi keilmuan yang dimiliki oleh setiap dosen. Dalam kesempatan ini program studi teknik mesin UMA berkesempatan melaksanakannya di desa Tanjung Rejo Kecamatan Percut Sei. Tuan yang meiliki objek wisata hutan magrove. Objek wisata tersebut terletak di pesisir pantai selat Melaka, dimana secara georafisnya memiliki potensi energi terbarukan, yaitu energi angin. Berdasarkan data pengukuran kecepatan angin rata-rata diperoleh 2 m/s. Dari potensi daya yang dapat dibangkitkan melalui turbin angin jenis horizontal secara reoritis 59,8 W. Secara aktual turbin ini memiliki daya rata-rata 20,9 W. Perbedaan ini terjadi sebabkan oleh faktor efisiensi sebesar 35%. Potensi energi angin Desa Wisata Tanjung Rejo sangat menjanjikan untuk pengembangan. Upaya ini tidak hanya akan meningkatkan kemandirian energi desa tersebut, tetapi juga mengurangi emisi karbon dan melestarikan lingkungan
Assessment of Plastic Distribution and Nutrient Flux in Kandolla Shella Stream at Usmanu Danfodiyo University, Sokoto State, Nigeria
Authors: Ayeni Joshua Adaviriku , Magami Ibrahim Muhammad 
Published: August 2024

Study’s Excerpt/Novelty

This study investigates plastic waste distribution and nutrient flux in the Kandolla Shella Stream, Nigeria, an area that has received limited attention in existing research.
The comprehensive analysis revealed the predominant presence of polyvinyl chloride near construction sites and highlighted the varying concentrations of nutrients, such as nitrate-nitrogen and phosphorus, between water and sediment samples.
These findings underscore the significant role of mineralization processes in nutrient accumulation within sediments, offering critical insights into the environmental impact of plastic pollution and nutrient dynamics in the region.

Full Abstract
Plastic waste has emerged as a significant global pollutant in aquatic ecosystems, drawing increasing worldwide attention from the scientific community. However, its impact has received comparatively less attention in Nigeria. This study aimed to assess plastic distribution and nutrient flux in the Kandolla Shella Stream. The Kandolla Shella stream was divided into four sampling points for the study. Standard analysis methods were adopted to assess plastic distribution and nutrient flux. Plastic samples were classified by polymer type, revealing a total weight of 341.8 grams. Polyvinyl chloride (205 grams) was found at only location A due to a nearby construction site. Polyethylene (79.5 grams), Polypropylene (29.6 grams), and Polyethylene terephthalate (27.3 grams) were present across all locations. Water and sediment samples were also evaluated, in which surface water pH ranged from 6.91-6.95 while in sediment from 6.77-6.99. Electrical conductivity varied in surface water (420-434 μs/m) and sediment (31.1-105.9 μs/m). Nitrate-nitrogen concentration was higher in water (5.675 mg/l) than in sediments (1.5 cmol/kg), while phosphorus concentration showed the opposite trend (sediments: 0.535 cmol/kg; water: 0.094 mg/l). Other chemical parameters exhibited higher concentrations in water but lower concentrations in sediments, except for potassium (sediments: 21.5 cmol/kg; water: 11.25 mg/l). The study observed the accumulation of important nutrients, particularly phosphorus, in sediments, emphasising the role of mineralisation processes near or below the bedrock interface along stream bottoms. Finally, the article provides valuable insights into plastic pollution and nutrient dynamics in the Kandolla Shella Stream.