bluuebunny/crossref_metadata_2025_split huggingface dataset:
Thyroid Carcinoma in Hot Nodules: Review of the Literature
Authors: Iranmanesh Pouya , Pusztaszeri Marc , Robert John , Meyer Patrick , Schiltz Boris , Sadowski Samira Mercedes , Goumaz Michel Olivier , Triponez Frederic 
Published: September 2013

ABSTRACT
Thyroid hot nodules are virtually always considered benign. Rare cases of hot thyroid carcinoma exist. We briefly described a clinical case and performed a review of the literature. We performed an extensive research on medical databases, such as PubMed and compiled all published cases matching preset criteria defining true hot thyroid carcinomas as well as guidelines regarding their management. We analyzed 103 articles published over the past 50 years. We selected 16 articles, including 45 cases matching our criteria. The majority were follicular carcinomas. Papillary carcinomas were infrequently found in this setting. Recommended management and survival rates were similar to classical cold thyroid cancer. Although hot nodules should continue to be considered benign most of the time, rare cases of hot thyroid cancers exist and clinicians should not hesitate to ask for additional tests if they encounter any abnormal finding. This form of thyroid cancer can reasonably be managed the same way as the cold thyroid cancers.

How to cite this article
Iranmanesh P, Pusztaszeri M, Robert J, Meyer P, Schiltz B, Sadowski SM, Goumaz MO, Triponez F. Thyroid Carcinoma in Hot Nodules: Review of the Literature. World J Endoc Surg 2013;5(2):50-54.
Autoimmune Rheumatic Disease (Polymyositis and Dermatomyositis) associated with Papillary Thyroid Carcinoma: Report of Two Cases and Review of the Literature
Authors: Lal Geeta , Bhama Anuradha R 
Published: September 2013

ABSTRACT
Autoimmune rheumatic diseases, such as polymyositis and dermatomyositis, have been demonstrated to carry a risk of the development of malignancy. Thyroid cancer is a rare occurrence in this setting; however, multiple cases have been reported. We present two cases of papillary thyroid carcinoma associated with dermatomyositis and polymyositis. The first patient is a 64-year-old female found to have papillary thyroid cancer after the diagnosis of polymyositis who underwent thyroid resection. The second patient is a 51-year-old male who was found to have synchronous papillary thyroid cancer and small cell carcinoma of the lung. He did not undergo thyroid resection due to widely metastatic lung cancer. We describe two cases of papillary thyroid cancer associated with autoimmune rheumatic disease. Though it is rare, thyroid cancer should remain in the differential diagnosis of a patient with new onset autoimmune rheumatic disease, as this may alter the eventual management of these patients.

How to cite this article
Lal G, Bhama AR. Autoimmune Rheumatic Disease (Polymyositis and Dermatomyositis) associated with Papillary Thyroid Carcinoma: Report of Two Cases and Review of the Literature. World J Endoc Surg 2013;5(2):55-58.
Recurrent Medullary Carcinoma detected by Gallium-68 Positron Emission Tomography
Authors: Soydal Cigdem , Araz Mine , Kucuk Ozlem N , Ozkan Elgin , Demirer Taner 
Published: September 2013

ABSTRACT
In this case, we would like to share our experience of a recurrent medullary thyroid cancer patient whose recurrence was detected by Ga-68 DOTATATE PET/CT.

How to cite this article
Soydal C, Ozkan E, Araz M, Kucuk ON, Demirer T. Recurrent Medullary Carcinoma detected by Gallium-68 Positron Emission Tomography. World J Endoc Surg 2013;5(2):59-60.
Gasless Transaxillary Thyroidectomy: A Technique of Endoscopic Thyroidectomy
Authors: Bhargav PRK 
Published: September 2013

ABSTRACT
Various endoscopic thyroidectomy (ET) techniques ranging from video-assisted, total endoscopic, transaxillary endoscopic, robotic and chest wall approaches have been reported for thyroid surgery. They can be broadly divided in to gas-dependent and gasless approaches. Here, we describe our technique of gasless transaxillary thyroidectomy with synergistic benefits of open and endoscopic thyroidectomies.

How to cite this article
Bhargav PRK. Gasless Transaxillary Thyroidectomy: A Technique of Endoscopic Thyroidectomy. World J Endoc Surg 2013;5(2):61-63.
Zerovalent Organometallics
Authors: Platt Andrew W.G. 
Published: September 2013

Abstract

The identification of lanthanide complexes by co‐condensation of metal atoms with carbon monoxide in matrix isolation experiments is described. Structures have been suggested on the basis of infrared spectroscopy and theoretical calculations. The reactions on lanthanide atoms with unsaturated aliphatic hydrocarbons led to the isolation of a variety of materials whose exact nature remains uncertain. Cyclooctatetraene forms ionic compounds with Ln
3+
ions as a result of its ability to form an aromatic dianion. The formation of bulk quantities of complexes with sterically demanding aromatic hydrocarbons and heteroaromatic compounds leads to sandwich‐type complexes. The compounds are thermodynamically stable for many of the lanthanides. The variations in stability have been correlated with the f→d promotion energy and the size of the lanthanide atoms. The compounds are all air and moisture sensitive, and other reactions such as substitution and reaction with compounds containing acidic hydrogen are described.
Photoluminescence of ZnO quantum dot films prepared by low temperature chemical vapor deposition
Authors: Zhang Xinyu , Kobayashi Kenkichiro , Tomita Yasumasa , Maeda Yasuhisa , Kohno Yosiumi 
Published: September 2013

AbstractFilms have been prepared at substrate temperatures of 125 to 200 °C by chemical vapor deposition. As a substrate temperature decreases, the grain sizes of the films are decreased. From transmission electron microscopic observation, the film grown at 125 °C is found to be constructed from ZnO quantum dots with 5 nm in diameter. Photoluminescence spectra in ultraviolet region at 40 K or less are assigned to both free electron‐acceptor and donor‐acceptor pair emissions, whereas photoluminescence spectra at temperatures higher than 50 K are due to the free electron‐acceptor emission. The peak energy of the free electron‐acceptor emission for the film deposited at 125 °C is 0.143 eV larger than that for the film deposited at 200 °C. The blue shift of the emission peak is ascribed to the quantum confinement effect. (© 2013 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Effects of Monoacylglycerols on Kinematic Viscosity and Cold Filter Plugging Point of Biodiesel
Authors: Dunn Robert O. 
Published: September 2013

AbstractBiodiesel is an alternative fuel composed of mono‐alkyl fatty acid esters made from the transesterification of plant oils or animal fats with methanol or ethanol. After conversion, biodiesel may contain trace concentrations of unconverted monoacylglycerols (MAG). These MAG have low solubility in biodiesel and may form solid residues when stored at cold temperatures. The present study evaluates the measurement of kinematic viscosity (ν) and cold filter plugging point (CFPP)‐time to filter (Δt) as parameters that predict the temperature where small concentrations of MAG may lead to formation of solids or other phase transitions that restrict the flow of soybean oil fatty acid methyl esters (SME) through filters and fuel lines. Mixtures of SME doped with MAG were prepared and ν and Δt were measured as the temperature decreased from 20 to below 0 °C. Results showed a correlation between ν and Δt that held for neat SME (SME without added MAG) and SME‐MAG mixtures as the temperature decreased to the threshold temperature (Tth). Sharp increases in Δt disrupted the correlation as temperature decreased below Tth. Furthermore, Tth generally increased as added MAG concentration increased in the mixtures.
Physicochemical Properties of Conjugated Linoleic Acid‐Rich Soy Oil
Authors: Ruan Chuan Min , Proctor Andrew 
Published: September 2013

AbstractCLA‐rich soy oil (CLARSO) has been produced by linoleic acid isomerization in soy oil TAG. The objective was to determine the physicochemical properties of the novel CLARSO relative to conventional refined bleached deodorized soy oil (RBDSO). Iodine value decreased in CLARSO samples despite unsaturation being unchanged, probably because conjugated double bonds in triacylglycerol (TAG) of CLARSO impede the complete addition of iodine. Thermal analysis by differential scanning calorimetry showed the melting point temperature increased with the increase in the CLARSO CLA concentration, and melting point broadening occurred in CLA contained samples. Dynamic viscosity of CLARSO conducted from 4 to 44 °C increased with the increase in CLA concentration, relative to RBDSO. Greatest viscosity differences occurred at the lower temperatures. Refractive indices and density were not greatly affected. The change in physical properties was attributed to the increased intermolecular hydrophobic interaction force due to conjugated double bonds and trans,trans isomers, relative to RBDSO. This may provide hard fat characteristics that may be useful for use in producing margarine or shortenings. Furthermore, the higher viscosity at refrigerator temperatures may be useful in salad oil and refrigerated sauces to enable suspension of particles and maintain a rich, thicker texture.
Addressing career barriers for high risk adolescent girls: The PATHS curriculum intervention☆
Authors: Doren Bonnie , Lombardi Allison R. , Clark Julie , Lindstrom Lauren 
Published: September 2013

AbstractThe study evaluated a gender‐specific comprehensive career development curriculum designed to target career barriers faced by high risk adolescent girls – those with disabilities and at risk for school failure. The goal of the curriculum was to promote social cognitive career and self determination outcomes associated with adaptive career development and adjustment. A pre‐post control group design was used to evaluate the curriculum. Findings suggest that participation in the curriculum resulted in significant and large gains in autonomy and in disability and gender‐related knowledge. Meaningful gains were noted in perceptions of social support and relevance of school. Participants in a high fidelity sample made significant and large gains in vocational skills self‐efficacy and disability and gender‐related knowledge. Meaningful improvements were noted in self‐advocacy, autonomy, and vocational outcome expectations. The findings suggest that the curriculum can improve important indicators of positive career development and adjustment in high risk adolescent girls.
Therapists’ professional and personal characteristics as predictors of outcome in long-term psychodynamic psychotherapy and psychoanalysis
Authors: Heinonen E. , Knekt P. , Jääskeläinen T. , Lindfors O. 
Published: September 2013

AbstractBackground:Whether long-term psychodynamic therapy (LPP) and psychoanalysis (PA) differ from each other and require different therapist qualities has been debated extensively, but rarely investigated empirically.Methods:In a quasi-experimental design, LPP was provided for 128 and PA for 41 outpatients, aged 20–46 years and suffering from mood or anxiety disorder, with a 5-year follow-up from start of treatment. Therapies were provided by 58 experienced therapists. Therapist characteristics, measured pre-treatment, were assessed with the Development of Psychotherapists Common Core Questionnaire (DPCCQ). General psychiatric symptoms were assessed as the main outcome measure at baseline and yearly after start of treatment with the Symptom Check List, Global Severity Index (SCL-90-GSI).Results:Professionally less affirming and personally more forceful and less aloof therapists predicted less symptoms in PA than in LPP at the end of the follow-up. A faster symptom reduction in LPP was predicted by a more moderate relational style and work experiences of both skillfulness and difficulties, indicating differences between PA and LPP in the therapy process.Conclusions:Results challenge the benefit of a classically “neutral” psychoanalyst in PA. They also indicate closer examinations of therapy processes within and between the two treatments, which may benefit training and supervision of therapists.
Cellular Reprogramming of Human Peripheral Blood Cells
Authors: Zhang Xiao-Bing 
Published: September 2013

Abstract
Breakthroughs in cell fate conversion have made it possible to generate large quantities of patient-specific cells for regenerative medicine. Due to multiple advantages of peripheral blood cells over fibroblasts from skin biopsy, the use of blood mononuclear cells (MNCs) instead of skin fibroblasts will expedite reprogramming research and broaden the application of reprogramming technology. This review discusses current progress and challenges of generating induced pluripotent stem cells (iPSCs) from peripheral blood MNCs and of in vitro and in vivo conversion of blood cells into cells of therapeutic value, such as mesenchymal stem cells, neural cells and hepatocytes. An optimized design of lentiviral vectors is necessary to achieve high reprogramming efficiency of peripheral blood cells. More recently, non-integrating vectors such as Sendai virus and episomal vectors have been successfully employed in generating integration-free iPSCs and somatic stem cells.
Clinical Therapy Using iPSCs: Hopes and Challenges
Authors: Lu Xiao , Zhao Tongbiao 
Published: September 2013

Abstract
Induced pluripotent stem cells (iPSCs) are generated by ectopic expression of defined transcription factors in somatic cells. They can undergo unlimited self-renewal and maintain the embryonic stem cells (ESCs)-like ability to differentiate into all three germ layers. iPSCs can potentially provide unlimited autologous cells for therapy and therefore hold great promise for regenerative medicine. Here we reviewed the recent advances in iPSC studies on disease modeling and clinical treatment as well as challenges correlated with clinical development of iPSCs, like tumorigenicity, immunogenicity and genomic instability.
Sexually transmitted infections and women's sexual and reproductive health
Authors: Gottlieb Sami L. , Newman Lori M. , Amin Avni , Temmerman Marleen , Broutet Nathalie 
Published: September 2013

AbstractSexually transmitted infections (STIs) are widespread globally and result in a large burden of sexual and reproductive health consequences that disproportionately affect women, including pregnancy complications, cancer, infertility, and enhanced HIV transmission. A new WHO publication, available online, outlines key points of action and new and future technologies for global STI prevention and control. Highlights from the WHO publication are described in the present article.
Why the bride wears white: Grounding gender with brightness
Authors: Semin Gün R. , Palma Tomás A. 
Published: September 2013

AbstractTwo studies examine the grounding of gender by the alignment of the female–male with the bipolar dimension of light–dark (most likely due to sexual dimorphism in skin pigmentation). We hypothesized and showed that in a speeded classification task male names are processed faster when they are presented in a black typeface (Exp. 1) or a dark color (Exp. 2) than when they are presented in white or a light color, with the opposite pattern for female names. The applied relevance of these findings is investigated in study 3 where lightness and darkness of consumables are revealed to drive gender specific preferences for foods and drinks, with the lighter consumables being female and darker ones being male preferences. Study 4 shows that gender preferences for consumer goods are uniformly driven by whether the good is in black or white, the former being male and the latter being female preference. The implications of these findings are discussed for theory formation in relation to the grounding of abstract concepts and in terms of how to design targeted marketing of products.
Competent in Competition and Health: Das gesundheitsökonomische Forschungszentrum CINCH
Authors: Felder Stefan , Herr Annika 
Published: September 2013

Einleitung
Kompetenz in den Bereichen Wettbewerb und Gesundheit ist Anspruch des gesundheitsökonomischen Forschungszentrums in Essen: CINCH – competent in competition and health. Mehr Wettbewerb im Gesundheitswesen kann den Zielkonflikt zwischen umfassender und qualitativ hochwertiger medizinischer Versorgung einerseits und Begrenzung von Kosten andererseits entschärfen. Wettbewerbsfragen liegen im Kernbereich gesundheitsökonomischer Forschung und werden im Rahmen von CINCH von zwei Nachwuchsgruppen und in ergänzenden Projekten untersucht.
Lebensqualität als Wettbewerbsvorteil in der frühen Nutzenbewertung
Authors: Klose Kristina , Witte Julian , Kreimeier Simone , Greiner Wolfgang 
Published: September 2013

Einleitung
Patientenberichtete Endpunkte (Patient-Reported Outcomes, PRO), wie die gesundheitsbezogene Lebensqualität (Health-Related Quality of Life, HRQoL), finden zunehmend Berücksichtigung im Bereich der Evaluation von Arzneimitteln. In diesem Beitrag wird der Stellenwert der HRQoL als patientenbezogener Endpunkt bei der frühen Nutzenbewertung von (neuen) Arzneimitteln in Deutschland vor dem Hintergrund der bisherigen Erfahrungen aufgezeigt.
International Health and the Limits of its Global Influence: Bhutan and the Worldwide Smallpox Eradication Programme
Authors: Bhattacharya Sanjoy 
Published: September 2013

AbstractHistories of the global smallpox eradication programme have tended to concentrate on the larger national formations in Africa and Asia. This focus is generally justified by chroniclers by the fact that these locations contributed a major share of the world’s annual tally of variola, which meant that international agencies paid a lot of attention to working with officials in national and local government on anti-smallpox campaigns in these territories. Such historiographical trends have led to the marginalisation of the histories of smallpox eradication programmes in smaller nations, which are presented either in heroic, institutional tropes as peripheral or as being largely shorn of sustained campaigns against the disease. Using a case study of Bhutan, a small Himalayan kingdom sandwiched between India and China, an effort is made to reclaim the historical experiences in small national entities in the worldwide smallpox eradication programme. Bhutan’s experience in the 1960s and 1970s allows much more in addition. It provides us with a better understanding of the limited powers of international agencies in areas considered politically sensitive by the governments of powerful nations such as India. The resulting methodological suggestions are of wider historical and historiographical relevance.
Successful use of a military-grade haemostatic agent for a major head and neck bleed
Authors: Crunkhorn R , Burnham R , Walton G 
Published: September 2013

AbstractBackground:Major haemorrhage is a catastrophic complication occurring in 3–4 per cent of head and neck cancer patients. Massive haemorrhage also causes 50 per cent of preventable deaths in combat situations. There has been a surge of interest in the development of effective haemostatic products in the military, with chitosan being one such product.Case report:A 48-year-old lady presented with a life-threatening head and neck bleed. She was known to have a malignant peripheral nerve sheath sarcoma originating from the left parapharyngeal space. Bleeding was successfully controlled with the application of Celox™ granules, a chitosan-based product currently used in the military.Conclusion:This paper describes the first known use of a military haemostatic agent to control a malignant head and neck bleed. Celox granules can be poured directly onto a wound to enhance haemorrhage control. The suggested mechanism of action and reports of current uses of haemostatic agents are described.
The Nature of Verbal Memory Impairment in Multiple Sclerosis: A List-Learning and Meta-analytic Study
Authors: Lafosse Jose M. , Mitchell Sandra M. , Corboy John R. , Filley Christopher M. 
Published: September 2013

AbstractThe primary purpose of this study was to test the hypothesis that multiple sclerosis (MS) patients have impaired acquisition rather than a retrieval deficit. Verbal memory impairment in MS was examined in 53 relapsing-remitting MS patients and 31 healthy controls (HC), and in a meta-analysis of studies that examined memory functioning in MS with list-learning tasks. The MS group demonstrated significantly lower acquisition and delayed recall performance than the HC group, and the meta-analysis revealed that the largest effect sizes were obtained for acquisition measures relative to delayed recall and recognition. Our data argue against a retrieval deficit as the sole explanation for verbal memory impairment in MS, and make a consistent case for the position that deficient acquisition contributes to the memory dysfunction of MS patients. Deficient acquisition may result from demyelination in relevant white matter tracts that reduces encoding efficiency as a result of impaired speed of information processing. (JINS, 2013,19, 995–1008)
all-trans-Retinoic acid improves immunocompetence in a murine model of lipopolysaccharide-induced immunosuppression
Authors: Martire-Greco Daiana , Landoni Veronica I. , Chiarella Paula , Rodriguez-Rodrigues Nahuel , Schierloh Pablo , Rearte Barbara , Isturiz Martin A. , Fernandez Gabriela C. 
Published: September 2013

Secondary infections due to post-sepsis immunosuppression are a major cause of death in patients with sepsis. Strategies aimed at restoring immune functions offer a new perspective in the treatment of sepsis. In the present study, we used LPS (lipopolysaccharide)-immunosuppressed mice to analyse the effects of ATRA (all-trans retinoic acid) on different immune parameters. The IS (immunocompromised) group had decreased lymphocyte and increased MDSC (myeloid-derived suppressor cell) counts in lymph nodes. They also had an impaired in vitro T-cell proliferation, mediated by MDSCs. ATRA administration restored T-cell proliferation, which was associated with a decreased number of live MDSCs. The IS group treated with ATRA had an increased number of CD4+ and CD8+ T-cells. ATRA partially improved the primary humoral immune response, even when immunosuppression was established first and ATRA was administered subsequently. Our results demonstrate that ATRA restores immunocompetence by modulating the number of leucocytes and the survival of MDSCs, and thus represents an additional potential strategy in the treatment of the immunosuppressive state of sepsis.
Facile synthesis of CuO–NiO nanocomposites with high surface areas and their application for lithium‐ion batteries
Authors: Chen Han , Li Chun‐Long , Li Na , Xiang Kai‐Xiong , Hu Zhong‐Liang 
Published: September 2013

CuO–NiO nanocomposites with high surface areas, which are used as anode materials for lithium‐ion batteries (LIBs), are successfully prepared by a facile wet‐chemical method. The CuO microspheres, NiO nanosheets and CuO–NiO nanocomposites were characterised by nitrogen adsorption, X‐ray diffraction, scanning electron microscopy, transmission electron microscopy and thermogravimetric analysis. The CuO–NiO nanocomposites composed of CuO microspheres and NiO nanosheets possess a high surface area of 158.0 m2 g−1. When the CuO–NiO nanocomposites are used as anode materials, they show an initial discharge and charge capacity of 886.7 and 638.8 mAh g−1. A high capacity of 562.5 mAh g−1 at 0.1 C was observed after 50 cycles, which is higher than CuO (345.9 mAh g−1 at 0.1 C after 50 cycles) and NiO (334.4 mAh g−1 at 0.1 C after 50 cycles), demonstrating that the CuO–NiO nanocomposites with high surface area show a better cycling performance than pure CuO and NiO. Therefore the CuO–NiO nanocomposites materials have a great potential application in LIBs.