bluuebunny/crossref_metadata_2025_split huggingface dataset:
Interaction between microbiome and testicular tissue mastocytes in male infertility
Authors: Faniev M. V. , Kadyrov Z. A. , Fedorenko T. V. , Prokopiev Ya. V. , Vodolazhsky D. I. , Sinitsyna A. R. 
Published: July 2024

Introduction. Male infertility is a complex condition with many potential causes, including hormonal imbalances, anatomical problems, genetic factors, lifestyle factors and more. But today, there is a fairly large group of infertile men with unknown causes of the disease.Objective. To analyze the taxonomic microbial diversity of testicular tissue and the urogenital tract of infertile men and to identify correlations between the microbiome and mastocytes in the testicular parenchyma.Materials & methods. The study was performed on testicular tissue samples from infertile patients with azoospermia (n = 33). All patients were divided into two groups based on the form of azoospermia: group 1 — infertile patients with non-obstructive azoospermia (NOA) (n=21); and group 2 — infertile with obstructive azoospermia (OA) patients (n=12). The bacterial diversity of testicular tissue was studied by the method of high-performance new generation sequencing (NGS). Immunohistochemical staining with anti-MCT (Anti-Mast Cell Tryptase) was used to determine the IHC expression of mastocyte markers.Results. The microbiome of patients with NOA differs markedly from the microbiome of patients with OA (p < 0.05). In group 1, representatives of the Enterobacteriaceae and Xanthomonadaceae families, the genera Finegoldia, Bifidobacterium, Porphiromonas, Prevotella, Peptoniphilus and Pseudomonas are significantly more often found. A distinctive feature of group 2 is the rare occurrence of the genus Prevotella. Histochemical analysis revealed mastocytosis in the in-between-canalicular stroma approximately in 83% of azoospermia cases. Mastocytes are found in tubule structures in 68% of cases and correlate with the microbiome of testicular tissue.Conclusions. Injuries caused by mastocytes in the stroma and tubular structures are interrelated with the taxonomic diversity of testicular tissue. Moreover, the testicles of NOA-patients have a qualitatively and quantitatively more diverse spectrum both at the level of families and genera, unlike OA-patients.
Evaluating the Adoption of mHealth Technologies by Community Health Workers to Improve the Use of Maternal Health Services in Sub-Saharan Africa: Systematic Review
Authors: Kachimanga Chiyembekezo , Zaniku Haules Robbins , Divala Titus Henry , Ket Johannes C.F , Mukherjee Joia S , Palazuelos Daniel , Kulinkina Alexandra V , Abejirinde Ibukun-Oluwa Omolade , Akker Thomas van den 
Published: July 2024

Background
Limited information exists on the impact of mobile health (mHealth) use by community health workers (CHWs) on improving the use of maternal health services in sub-Saharan Africa (SSA).

Objective
This systematic review addresses 2 objectives: evaluating the impact of mHealth use by CHWs on antenatal care (ANC) use, facility-based births, and postnatal care (PNC) use in SSA; and identifying facilitators and barriers to mHealth use by CHWs in programs designed to increase ANC use, facility-based births, and PNC use in SSA using a sociotechnical system approach.

Methods
We searched for articles in 6 databases (MEDLINE, CINAHL, Web of Science, Embase, Scopus, and Africa Index Medicus) from inception up to September 2022, with additional articles identified from Google Scholar. After article selection, 2 independent reviewers performed title and abstract screening, full-text screening, and data extraction using Covidence software (Veritas Health Innovation Ltd). In addition, we manually screened the references lists of the included articles. Finally, we performed a narrative synthesis of the outcomes.

Results
Among the 2594 records retrieved, 10 (0.39%) studies (n=22, 0.85% articles) met the inclusion criteria and underwent data extraction. The studies were published between 2012 and 2022 in 6 countries. Of the studies reporting on ANC outcomes, 43% (3/7) reported that mHealth use by CHWs increased ANC use. Similarly, of the studies reporting on facility-based births, 89% (8/9) demonstrated an increase due to mHealth use by CHWs. In addition, in the PNC studies, 75% (3/4) showed increased PNC use associated with mHealth use by CHWs. Many of the studies reported on the importance of addressing factors related to the social environment of mHealth-enabled CHWs, including the perception of CHWs by the community, trust, relationships, digital literacy, training, mentorship and supervision, skills, CHW program ownership, and the provision of incentives. Very few studies reported on how program goals and culture influenced mHealth use by CHWs. Providing free equipment, accessories, and internet connectivity while addressing ongoing challenges with connectivity, power, the ease of using mHealth software, and equipment maintenance support allowed mHealth-enabled CHW programs to thrive.

Conclusions
mHealth use by CHWs was associated with an increase in ANC use, facility-based births, and PNC use in SSA. Identifying and addressing social and technical barriers to the use of mHealth is essential to ensure the success of mHealth programs.

Trial Registration
PROSPERO CRD42022346364; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=346364
The phenomenon symptoms experienced of long covid-19 by students’ survivor after confirmed covid-19
Authors: Ruhyanudin Faqih , Afandi Irvan , Rahayu Henik Tri , Nur Rohmah Anis Ika , Purwanto Edi , Agustiyaningsih Titik , Ubaidillah Zaqqi , Alhusna Chairul Huda , Sunardi Sunardi , Herawati Tiwuk , Syamsiah Anwar Jamilatus 
Published: July 2024

Introduction: COVID-19 survivors often experience symptoms of recurrence or symptoms similar to those when confirmed positive. COVID-19 also has an impact on the physical, psychological, and spiritual health aspects of its survivors. This research aims to determine the health status of COVID-19 survivors after confirmation. Objectives: This research aims to determine the health status of COVID-19 survivors after confirmation. Methods: This quantitative descriptive research was conducted on 65 nursing students in Malang who were selected using the Accidental Sampling technique. Data was collected by providing an online questionnaire via Google Forms. The instruments used in this research were the post-COVID-19 Recovery Clinic Baseline Questionnaire, DASS-21, and the Spiritual Attitude and Involvement List (SAIL). The data was analyzed using Descriptive Analysis. Results: Research shows that the most common physical signs and symptoms during confirmed COVID-19 are loss of taste and smell, fever, shortness of breath, cough, and fatigue. Meanwhile, the symptoms still felt after recovery are changes in the color of the fingers, rashes, diarrhea, and hoarseness. Cough without phlegm and mucus occurred in 43.1%, and shortness of breath was experienced by 42.9% of respondents in the moderate category. Fatigue in the moderate category was felt by 58.3% of respondents. The results of psychological status showed that depression symptoms in the moderate and very severe category were 46.2%, anxiety in the very severe category was 75.4%, and stress symptoms in the very severe category were 38.5%. Regarding spiritual status, the majority are in the sufficient category, namely 68%. Conclusions: Some of the physical signs and symptoms, psychological changes, and spiritual status at the time of confirmation of COVID-19 are still felt even though they have been declared hostile to COVID-19.
Development of Marketing Management Learning Model Based on E-Potofolio in Business Administration Department of Malang State Polythecnic
Authors: Maskan Mohammad , Maskur  , Fauzi Achmad 
Published: July 2024

The current lecture approach demands student activity, so that students can build their own knowledge in the learning process. The student center learning (SCL) approach would be more appropriate to the current situation and conditions, where the lecturer acts as a facilitator, mediator and motivator for students in learning because students can learn from various learning sources, such as: textbooks, business experts, the internet, mass media, electronic media or the business environment that surrounds the student's residence. In addition, the assessment of students is also more comprehensive and includes three aspects, namely cognitive, affective and psychomotor. One such learning model is to use the E-Portfolio approach. This is in accordance with the objectives of marketing learning at the Department of Commerce Administration, State Polytechnic of Malang, which was given in semester 1, which emphasized the achievement of the three learning domains, namely: cognitive, affective and psychomotor. The implementation of marketing learning based on E-Portfolio will raise the enthusiasm of lecturers in teaching, because the content and presentation of learning materials involve students actively and go directly to the field. As for students, it will generate attitudes and marketing motivation and be able to understand the focus of the material discussed, because the lecture material is easier to digest because it is based on direct observation and experience in the field. Based on data analyze of research found that research result show E-Portfolio Model can be applied at Marketing Management learning at Commerce Administration, State Polytechnic of Malang.
Improvisasi Algoritma RSA Menggunakan Generate Key ESRKGS pada Instant Messaging Berbasis Socket TCP
Authors: Aditya Gadhing Putra , Aminuddin Aminuddin , Arifianto Sofyan 
Published: July 2024

Socket TCP adalah abstraksi yang digunakan aplikasi untuk mengirim dan menerima data melalui koneksi antar dua host dalam jaringan komputer. Jaringan yang biasa kita gunakan bersifat publik yang sangat rentan akan penyadapan data. Masalah ini dapat teratasi dengan menggunakan algoritma kriptografi pada socket TCP, salah satunya menggunakan algoritma RSA. Tingkat keamanan algoritma RSA standar memiliki celah keamanan pada kunci publik ataupun privat yang berasal dari inputan 2 bilangan prima saat pembangkitan kunci, begitupun dengan algoritma improvisasi RSA meskipun menggunakan 4 bilangan prima akan tetapi mulai dari pembangkitan kunci hingga dekripsi memiliki proses yang sama persis dengan RSA standar sehingga tingkat keamanan dari kedua algoritma tersebut sama – sama kurang aman meskipun jumlah bilangan prima dari algoritma improvisasi RSA lebih banyak dari RSA standar. Peningkatan keamanan dapat dilakukan dengan memodifikasi algoritma RSA dengan menggunakan ESRKGS (Enhanced and Secured RSA Key Generation Scheme). ESRKGS RSA memiliki kelebihan yang utama pada segi keamanannya. ESRKGS RSA secara total memodifikasi algoritma RSA terutama pada bagian pembangkitan kunci dan diklaim mempunyai performa lebih cepat dari algoritma improvisasi RSA yang sama – sama menggunakan 4 bilangan prima dan tentunya lebih aman dari serangan known plaintext attack dan fermat factorization attack yang akan penulis gunakan untuk pengujian keamanan pada penelitian ini. Hasil pengujian performa waktu pembangkitan kunci dengan panjang bit 256 bit, 512 bit, dan 1024 bit serta untuk proses enkripsi dan dekripsi panjang karakter yang digunakan adalah 100, 250, dan 400 menunjukkan bahwa algoritma ESRKGS RSA lebih baik dibandingkan algoritma improvisasi RSA. Pengujian kemanan menggunakan known plaintext attack dan fermat factorization attack menunjukkan bahwa algoritma ESRKGS RSA lebih baik dibandingkan algoritma RSA standar dan improvisasi RSA.
Penerapan Metode SDLC RUP (Rational Unified Proses) Dalam Pembuatan Sistem Informasi E-kos Berbasis Web
Authors: Young Sandy , Nuryasin Ilyas , Suharso Wildan 
Published: July 2024

Sistem informasi saati ini semakin berkembang pesat. Teknologi di era sekarang sangat membantu semua orang agar lebih mudah dan lebih efektif penggunaannya. Termasuk didalamnya untuk membantu pemilik kost untuk menyebarkan info tentan indekosnya dan mahasiswa untuk mencari tempat indekos terdekat dengan kampus. Kebutuhan akan indekos yang sangat penting bagi mahasiswa yang melakukan studi dalam waktu yang lama dan membutuhkan tempat tinggal.Website indekos ini akan menggunakan Rational Unified Process (RUP) sebagai metode pengembangan sistem untuk membangun website ini. Dari permasalahan yang ada, maka di dapat topik yang dapat diangkat menjadi bahasan dengan judul “Penerapan Metode SDLC RUP (RATIONAL UNIFIED PROSES) Dalam Pembuatan Sistem Informasi E-kos Berbasis Web”.Rational Unified Process memiliki 4 fase yaitu inception, elaboration, Construction, Transition dan disetiap fase memiliki tugasnya masing-masing[1]. Inovasi tersebut dapat mempermudah mahasiswa mencari tempat indekos dan membantu pemilik indekos untuk membantu mempromosikan kostnya serta informasi infokosnya yang detail.
Rekomendasi Lowongan Pekerjaan dari Portal Bursa Lowongan Kerja Memanfaatkan Cosine Similarity dan Simple Additive Weighting
Authors: Ningsih Rahma , Azhar Yufis , Munarko Yuda 
Published: July 2024

Pencarian informasi melalui portal bursa lowongan kerja memanfaatkan mesin pencari (search engine) yang terdapat pada situs layanan. Hasil pencarian oleh sistem didasarkan pada kesamaan query inputan, kemudian hasilnya ditampilkan dengan model sortir yang terbatas pada hierarkis abjad atau angka. Sehingga diperlukan waktu lagi untuk memilah informasi yang dibutuhkan, karena hasil informasi yang ditampilkan sistem juga diantaranya merupakan informasi yang kurang sesuai. Sebab itu diperlukanlah adanya pengembangan model perankingan terhadap rekomendasi informasi dari hasil pencarian tersebut. Metode cosine similarity dalam pengimplementasiannya menghasilkan data sesuai dengan query yang diinputkan user, serta ditambah dengan menerapkan metode simple additive weighting sebagai metode perankingan terhadap data retrive hasil cosine similarity. Sistem memiliki fitur unggulan, yaitu model perankingan yang bertingkat sehingga user dapat menentukan sendiri aturan perankingan dengan menentukan kriteria mana yang cendrung dominan.
Rancang Bangun Sistem Manajemen Pergudangan Berbasis Website pada PT. Astragraphia (Cabang Depo Jayapura)
Authors: Taslim Sahnaz Faradiba , Nuryasin Ilyas , Suharso Wildan 
Published: July 2024

PT. Astragraphia adalah perusahaan yang bergerak pada bidang industri yang dimana aktivitas pengelolaan rantai supplynya harus dijaga dan ditingkatkan , pada bagian pergudangan diperusahaan ini terdapat masalah yaitu dimana belum tersedianya sistem manajemen pergudangan yang bisa diakses di luar lingkungan perusahaan sehingga kurang optimalnya jam kerja karyawan karena harus kembali ke kantor untuk melakukan pengecekan stok barang ataupun memberikan validasi barang yang berupa invoice. Pada saat ini PT. Astragraphia telah memiliki aplikasi namun hak akses aplikasi tersebut terbatas hanya dilingkungan perusahaan sehingga menyulitkan karyawan jika berada diluar perusahaan. Dengan ini menjadikan tidak efektifnya jam kerja karyawan jika ingin mengecek barang, mengorder barang ke pusat dan juga menyerahkan bukti pembelian barang yang berupa invoice kepada pelanggan. Berdasarkan pemasalahan diatas penelitian ini bertujuan untuk membangun sebuah sistem manajemen pergudangan berbasis website dengan menggunakan framework CodeIgniter dan metodologi yang digunakan SDLC (System Development Life Cycle) model Waterfall guna untuk memaksimalkan kegiatan pengolahan data barang pada gudang cabang depo Jayapura. Hasil dari penelitian ini adalah Rancang bangun sistem manajemen pergudangan yang akan membantu kegiatan pengolah data barang yang masuk dan keluar, penyuplai, transaksi pelanggan dan pembuatan laporan barang.
Sistem Perekomendasi Dosen Pembimbing berdasarkan Relevansi Topik Tugas Akhir menggunakan Metode Okapi BM25
Authors: Agustina Meilina , Azhar Yufis , Hayatin Nur 
Published: July 2024

Sistem rekomendasi adalah sebuah perangkat lunak untuk memberikan rekomendasi kepada pengguna mengenai produk yang dapat digunakannya. Masalah administrasi di kantor jurusan Pendidikan Guru Sekolah Dasar Universitas Muhammadiyah Malang merupakan salah satu permasalahan yang selalu dihadapi oleh para staf TU dan part timer. Penggunaan sistem manual yang masih berjalan saat ini dinilai kurang efektif terhadap waktu, tempat, dan tenaga sehingga diperlukan adanya bantuan berupa sistem informasi. Pada perancangan sistem informasi ini akan menggunakan metode Okapi BM25 dimana metode ini merupakan fungsi peringkat yang digunakan oleh mesin pencari (search engine) untuk peringkat dokumen pencocokan sesuai relevansinya dengan permintaan pencarian yaitu berupa topik tugas akhir. BM25 memiliki fungsi yang sesuai dengan 3 prinsip pembobotan yang baik, yaitu memiliki inverse document frequency (idf), term frequency (tf), dan memiliki fungsi normalisasi dari panjang dokumen (document length normalization).
Sistem Administrasi Kependudukan di Desa Mekarsari Berbasis Java Desktop
Authors: Wildan Wildan , Prasetya Rendi , Rismawati Nofita 
Published: July 2024

Pada saat ini sistem berbasis komputer banyak diterapkan pada kegiatan pelayanan, dengan diterapkannya sistem ini diharapkan dapat menambah kualitas dari pelayanan. Setiap warga negara juga berhak atas pelayanan publik yang baik, penjelasan tersebut terdapat dalam Undang-Undang Nomor 25 Tahun 2009 tentang pelayanan publik dimana negara berkewajiban melayani setiap warga negaranya dan Undang-Undang Nomor 2 Tahun 2017 tentang standar pelayanan minimum Desa. Pada sistem yang berjalan saat ini Desa Mekarsari membutuhkan waktu lama dalam melayani penduduk dan menghambat kinerja staf, karena pengolahan data yang tidak efisien. Berpikir bahwasannya sistem masih kurang efisien, maka dibangunlah sebuah sistem administrasi kependudukan di Desa Mekarsari berbasis desktop. Dengan dibangunnya sistem ini diharapkan dapat membuat sistem yang sesuai dengan kebutuhan, mudah digunakan, dan pembuatan laporan yang cepat, tepat dan akurat, sehingga tujuan mempermudah dalam pelayanan administrasi akan tercapai. Metode dalam membangun sistem yang digunakan adalah waterfall, dengan tahapan-tahapan pada metode waterfall ini sistem administrasi yang dibangun akan sesuai dengan kebutuhan Desa Mekarsari.
The Role of Pharmacists in Health Promotion
Authors: Dave Pallav 
Published: July 2024

Health promotion is regarded as instrumental in addressing the growing public healthcare concerns. It is recognized as instrumental in disease prevention and control. Health promotion can also be used as an instrumental tool to address the growing cases of non-communicable diseases. Health promotion is regarded as effective in disease prevention and control because it emphasizes the need for individuals to be in control over their own health. However, despite the significance of health promotion in disease prevention and control, it remains largely underutilized. One of the reasons why health promotion is underutilized is because of the lack of adequate healthcare personnel to take on health promotion initiatives. Expanding the role of pharmacists to include more involvement in health promotion initiatives can help to fill this gap. Some of the measures and initiatives pharmacists can get involved in are being part of building public health policies, creating supportive environments, providing health education, being in community action, ensuring medication safety, and disease prevention and control. To enable pharmacists to perform these measures effectively, there is a need to address the existing barriers and challenges. This will lead to positive outcomes and ensure pharmacists perform their roles effectively to enhance health promotion.
Keywords: health promotion, pharmacists, health education, disease prevention and control, immunization
INTERTEXTUALIDADE, MULTIMODALIDADE E CONTEXTO: UMA PROPOSTA PARA A COMPREENSÃO LEITURA NA PERSPECTIVA DA LINGUÍSTICA TEXTUAL
Authors: Nonato de Oliveira Raimundo 
Published: July 2024

O presente artigo inscreve-se na área de Linguística Textual e traz os conceitos de intertexto, contexto e multimodalidade. Neste sentido, fica o seguinte questionamento: de que maneira esses conceitos contribuem para uma proposta de leitura na perspectiva da linguística textual? Diante disso, elegemos como objetivo principal realizar um estudo sobre esses conceitos e promover uma aplicação de proposta de leitura a partir da capa de jornal “O Estado de Minas” publicada num suporte digital. Para alcançar os objetivos, optamos por uma leitura ampliada em que sejam mobilizados os recursos textuais para a análise, mediante uma revisão bibliográfica. A interpretação do material coletado, seguirá os conceitos de texto, intertexto e contexto de Beaugrande (1997), Cavalcante, Oliveira (2019), Elias, Cavalcante (2017) Koch, Elias (2016), Koch (2005) e multimodalidade de Kress e van Leeuwen (2006 [1996]). Pressupondo que a leitura é uma estratégia potente quando dialoga com as necessidades e urgências do processo de construção do conhecimento, ao abordar o texto de modo a considerar os conceitos supracitados, esperamos refletir o processo de leitura para além do textual, para a construção do conhecimento.
Partner-Level Cumulative Industry Expertise and Audit Quality
Authors: Jiang Like , Naiker Vic , Wang Yu , Zhang Shafu 
Published: July 2024

SUMMARY
We employ a novel framework to evaluate the audit quality implications of cumulative industry expertise that audit partners acquire from auditing public clients across their careers. Leveraging the historical data of audit partner engagements with public clients in China, we find that the development of cumulative industry expertise is explained by various experiences of the partners in their initial year of handling public clients, as well as the growth, homogeneity, and demand for specialized knowledge in an industry. Our main results reveal a positive and significant association between partner cumulative industry expertise and different proxies of audit quality. We also find that many partners deemed specialists based on the largest market shares in a given year do not possess a high level of cumulative industry expertise and are insignificantly associated with audit quality. Our findings highlight the importance of adopting a cumulative perspective to study partners’ industry expertise.
Enhanced pendulum appliance utilizing temporary anchorage device-based Nance arch and modified springs for optimized molar distalization control: a case report
Authors: Sun Chuanxi , Zhou Ziqi , Shi Hui , Algahefi Ahmed , Li Zhihua 
Published: July 2024

ABSTRACT
A 20-year-old female patient with severe maxillary crowding and skeletal Class III malocclusion was successfully treated using an enhanced pendulum appliance. Camouflage treatment was chosen because the patient refused surgical intervention. Detailed examination and analysis revealed that labial inclination of the maxillary anterior teeth could provide the alignment space necessary after tooth extraction in the maxillary arch but it would not be beneficial esthetically and would increase the moment perpendicular to the tooth long axis as well as increase the risk of bone dehiscence. Therefore, lingual inclination of the mandibular anterior teeth was performed. To create space for aligning the maxillary arch, an enhanced pendulum appliance was utilized, in addition to premolar extraction. The enhanced pendulum appliance had one mesial and one distal helix on each spring, exerting opposing forces in the buccolingual direction and reducing the buccolingual inclination of the molars. In addition, miniscrews were integrated into the Nance arch of the enhanced pendulum appliance to provide skeletal anchorage, minimizing the reciprocal movement of anchorage teeth. This modification not only enhanced control over tooth movement but also improved treatment efficiency. During the entire treatment duration of 17 months, substantial improvement in facial and occlusal aspects were noted. Additionally, the patient retained these positive changes until the subsequent 2-year follow-up period.