bluuebunny/crossref_metadata_2025_split huggingface dataset:
Role of integrated pulmonary index in respiratory monitoring of spontaneously breathing COVID-19 patients with moderate to severe respiratory symptoms
Authors: Kasem Sahar Mahmoud , Ahmed Maysa Kamal , Mukhtar Ahmed Muhammed , Abdelbary Akram Ahmed , Eladawy Akram Shahat , Maher Mohamed Ahmed , Farouk Sara 
Published: July 2024

Background & objective: Most of the COVID-19 patients suffered from moderate to severe respiratory symptoms. Many of them needed oxygen supplementation or even mechanical ventilation. There is little data available about the use of either end-tidal CO2 (EtCO2) or integrated pulmonary index (IPI) in these patients. The aim of this study to investigate the difference in IPI values for subjects requiring mechanical ventilation compared to those managed without ventilation and the correlation between EtCO2 and SpO2.
Methods: This prospective observational study involved adult COVID-19 patients admitted to the ICU with moderate to severe respiratory symptoms. All patients were connected to a portable respiratory monitor with the IPI algorithm (Medtronic Capnostream 35) and treated according to a standardized protocol. Oxygen flow was adjusted to maintain oxygen saturation (92–96%). If the respiratory rate did not fall below 30 breaths per minute and/or the SpO2 did not reach the target, non-invasive ventilation (NIV) was initiated. Patients with NIV failure was eligible for invasive mechanical ventilation.
Results: SpO2 was significantly lower, while RR was significantly higher in intubated group compared to non- intubated group (P < 0.001 and 0.018, respectively). However, IPI, EtCO2, and HR did not differ among both groups. There was a significant positive correlation between EtCO2 and SpO2 at baseline before oxygen therapy (r = 0.419; P = 0.007). There was a significant negative correlation between CT score and SpO2 (r = -0.408; P = 0.01); however, there was no correlation between CT score and both IPI and end tidal CO2 at baseline (r = 0.017; P = 0.9).
Conclusion: The integrated pulmonary index cannot be used as a single parameter for assessing respiratory severity in COVID-19 patients.
Abbreviations: EtCO2 - end-tidal CO2; IPI - integrated pulmonary index; NIV - non-invasive ventilation;
Keywords: Integrated Pulmonary Index, COVID-19, EtCO2, CT severity score.
Citation: Kasem SM, Ahmed MK, Mukhtar AM, Eladawy AS, Maher MA, Farouk S. Role of integrated pulmonary index in respiratory monitoring of spontaneously breathing COVID-19 patients with moderate to severe respiratory symptoms. Anaesth. pain intensive care 2024;28(2):446−451; DOI: 10.35975/apic.v28i3.2460
Received: January 09, 2024; Reviewed: March 24, 2024; Accepted: March 24, 2024
Intergenerational workforce: synergism for the benefit of clinical practice
Authors: Degrandi Oliveira Carlos R. 
Published: July 2024

Rapidly increasing world population has forced the governing authorities to increase the pace of the expansion of the healthcare facilities. It has resulted in more and more health related institutions, with more requirement of work force as well as the latest technology-based gadgets. All these factors have lead to healthcare teams with diverse age groups, diverse technical knowledge and skills and divers clinical experiences. This editorial sheds some light on the positive aspects of this deversity in unity.
Keywords: Diversity; Generations; Intergenerational diversity; Synergy; Workforce
Citation: Oliveira CRD. Intergenerational workforce: synergism for the benefit of clinical practice. Anaesth. pain intensive care 2024;28(3):402−404; DOI: 10.35975/apic.v28i3.2476
Received: April 28, 2024; Accepted: May 05, 2024
The impact of thyroid hormone levels and APACHE II scores on the clinical outcome in critically ill patients
Authors: Wironegoro Rio , Suhardi Christian Julio , Maulydia Maulydia , Wibisono Sony , Adi Soebagijo , Rahmaweni Rahmaweni 
Published: July 2024

Background & objective: Thyroid hormone levels are often raised during stress and acute illness. APACHE II score has been linked to adverse outcome after severe disease. We analyzed the impact of the level of free triiodothyronine (fT3), free thyroxine (fT4), thyroid stimulating hormones (TSH), and APACHE II scores on the outcome of critically ill patients admitted to Intensive Care Unit (ICU).
Methodology: A cohort prospective study was conducted on critically ill patients in the ICU. Patients’ baseline data, thyroid hormone levels, including fT3, fT4, TSH, and APACHE II score within 24 h of admission were compared between 30-day survivors and non-survivors. Multivariate Cox proportional hazards regression analysis was conducted to assess the risk factors for mortality.
fT3Non-survivors were significantly older than survivors (55.81 ± 12.61 vs 41.40 ± 11.40, P = 0.003). The APACHE II score was higher in non-survivors (25.88 ± 9.28 vs 22.13 ± 10.42, P = 0.299). Thyroid hormone levels showed no significant difference between the two groups. The area under the receiver-operating curve for APACHE II was 0.610 (0.403-0.818), and for fT3 was 0.523 (0.311-0.735).
Conclusion: Although there was no significant difference in thyroid hormone levels between the survivors and non-survivors, the results of this study show that low fT3 levels and high APACHE II scores had a more significant association with adverse clinical outcomes in critically ill patients.
Abbreviations: APACHE - Acute Physiology and Chronic Health Evaluation; ESS - Euthyroid Sick Syndrome; ft3 - Free Triiodothyronine; ft4 - Free Triiodothyronine; NTIS - Non-Thyroidal Illness Syndrome; TSH - Thyroid Stimulating Hormone
Keywords: Critically ill; Mortality; fT3 level; fT4 level; APACHE II score
Citation: Wironegoro R, Suhardi CJ, Maulydia, Wibisono S, Adi S, Rahmaweni R. The impact of thyroid hormone levels and APACHE II scores on the clinical outcome in critically ill patients. Anaesth. pain intensive care 2024;28(3):416−422; DOI: 10.35975/apic.v28i3.2478
Received: March 03, 2024; Revised: April 13, 2024; Accepted: April 15, 2024
Bertolotti's syndrome as an uncommon cause of LBP; a case series
Authors: Ali Liaqat , Abbas Muhammad Ali , Hanif Huma , Nasir Sana , Ali Umer 
Published: July 2024

Lumbosacral transition of L5 vertebra is an anatomical variation. The transverse process of L5 vertebra may become enlarged and form a pseudo joint with ilium or sacrum, leading to low back pain, especially in young adults due to change in biomechanical properties of the lumber spine. This condition is referred to as Bertolotti’s syndrome. Here we report an ongoing case series of 11 of our patients in whom we studied the impact of steroid and local anesthetic infiltration as a treatment approach.
The primary objective of this case series is to comprehensively investigate and report the clinical characteristics, radiological findings, treatment modalities, and outcomes in a group of 11 patients diagnosed with Bertolotti's syndrome, thus adding to the existing body of knowledge about Bertolotti's syndrome by focusing on its occurrence and management in younger individuals, which is relatively less explored in the literature.
Abbreviations: VAS - Visual Analogue Scale; FABER - Flexion Abduction External rotation; SLR - Straight Leg Raising
Keywords: Bertolotti's Syndrome, Low back pain, Lumbosacral transition
Citation: Ali L, Abbas MA, Hanif H, Nasir S, Ali U. Bertolotti's syndrome as an uncommon cause of LBP; a case series. Anaesth. pain intensive care 2023;27(6):593−599; DOI: 10.35975/apic.v28i3.2484
Received: January 28, 2024; Reviewed: March 19, 2024; Accepted: April 03, 2024
RAQUIANESTESIA NA PRÁTICA CIRÚRGICA: BENEFÍCIOS E DESAFIOS
Authors: Camargo Marília Ferreira , Silva Danillo Pedro Mendes da , Menezes Gabriel Barbosa , Santos Ana Clara Andrade Noronha , Silva Roger Andrade Da , Pontifícia Aline Cristina da Silva Duarte , Ripari Vitória Alagia , Silveira Luísa Teixeira , Lima Delza Correia , Coscia Bárbara Cirilo de Sá , Silva Geovanna Beatriz de Arruda e , Pinto Maria Queiroga , Costa Débora Morgana Bezerra da , Cunha Brunno Alexandre Pereira da 
Published: July 2024

A raquianestesia, também conhecida como anestesia espinhal, é uma técnica anestésica regional amplamente utilizada em diversas cirurgias, principalmente em procedimentos abaixo do abdômen. Esta abordagem oferece inúmeros benefícios, incluindo uma rápida indução anestésica, estabilidade hemodinâmica e menor risco de complicações respiratórias em comparação com a anestesia geral. No entanto, a prática da raquianestesia também apresenta desafios significativos, como a potencial ocorrência de hipotensão e cefaleia pós-punção dural. Objetivo: Explorar e analisar a aplicação da raquianestesia em procedimentos cirúrgicos, destacando suas vantagens e desafios. Metodologia: Foram utilizadas as bases de dados Cochrane, Scielo e Medline, buscando artigos publicados entre os anos de 2023 e 2024, nos idiomas Português ou Inglês. Considerações Finais: A raquianestesia é valorizada na prática cirúrgica por sua rápida indução e menores complicações respiratórias em comparação com a anestesia geral. No entanto, apresenta desafios como hipotensão e cefaleia pós-punção dural. Assim, o sucesso dessa técnica depende da habilidade do anestesiologista e do manejo eficaz dos efeitos adversos, bem como investir em educação contínua e pesquisa é essencial para aprimorar a segurança e a eficácia da raquianestesia.
ANALISIS INFORMASI KEUANGAN DALAM MENGEVALUASI KINERJA PEMERINTAHAN KABUPATEN DELI SERDANG
Authors: Purba Sahala , Nadeak Heri Imanuel , Siregar Elizabeth , Damanik Nia Tabita , Purba Dian Herdeliani 
Published: July 2024

Penelitianl ini bertujuanl untuk menganilisis Kinerjal Keuangan Pemerintahl Kabupaten Simalungun untuk tahunl anggaran 2013 - 2022 dilihatl dari : (1) Rasiol Kemandirian Keuanganl Daerah, (2) Rasiol Ketergantungan Keuanganl Daerah, (3) Rasiol Derajat Desentralisasi Fiskal, (4) Rasiol Efektifitas Pendapatan Asli lDaerah, (5) Rasiol Efisiensi Pendapatan Asli lDaerah, (6) Rasiol Efektifitas Pajakl Daerah, (7) Rasiol Efisiensi Pajakl Daerah, danl (8) Rasiol Derajat Kontribusil BUMD. Pengumpulan data menggunakan metode sampling.lllllllllllllllllllllllllllllllllllllll
PENINGKATAN KEMAMPUAN PERTOLONGAN PERTAMA ANGGOTA PMR DALAM PENANGANAN CEDERA JARINGAN LUNAK DI SMK CENDIKA BANGSA
Authors: Ratna Mi'asih Wiwit , Nafisa Adita 
Published: July 2024

Cedera atau kecelakaan ringan dapat dialami siapa saja di lingkungan terdekat khususnya sekolah. Oleh karena itu sudah sepatutnya sekolah memiliki eksrakurikuler yang dapat menjadi rujukan Ketika terjadi hal-hal tersebut. Salah satunya adalah Ekstrakurikuler Palang Merah Remaja (PMR) yang merupakan salah satu ektrakurikuler yang cukup menarik, karena siswa akan cenderung banyak berlatih mengenai penanganan P3K. Program pengabdian Kepada Masyarakat ini menggunakan metode pelatihan dalam upaya pertolongan pertama pada perawatan cedera jaringan lunak bagi siswa Palang Merah Remaja SMK Cendika Bangsa. Setelah dilakukan pelaksanaan kegiatan pengabdian kepada Masyarakat, kepada peserta siswa Palang Merah Remaja SMK Cendika Bangsa, maka hasil yang diperoleh dari kegiatan tersebut adalah : 1. Terlaksananya edukasi dalam upaya memberikan pengetahuan dan pemahaman tentang perlunya perawatan cedera jaringan lunak kepada anggota Palang Merah Remaja SMK Cendika Bangsa. 2. Terlaksananya pelatihan perawatan cedera jaringan lunak dengan melibatkan peserta siswa-siswi anggota Palang Merah Remaja SMK Cendika Bangsa untuk dapat meningkatkan perawatan luka dalam aktivitas sehari-hari, baik menolong diri sendiri, keluarga maupun orang lain. 3. Anggota PMR SMK Cendika Bangsa mampu menerapkan bagaimana cara penanganan serta pencegahan cedera agar tidak semakin fatal sebelum dirujuk ke fasilitas Kesehatan.
Effect of Perturbation Training and Dynamic Resistance Exercises in Patients with Grade II Knee Osteoarthritis: Case Report
Authors: Madhuripu P  , M.Premkumar  , Aishwarya Nitin Sonwane  , Kamalakannan R  , Arun Krishnan  
Published: July 2024

Osteo Arthritis of the knee manifests as stiffness, mobility restriction, and difficulty with daily activities. Perturbation training, a method for fostering the growth of motor abilities, whereas resistance training improves physical function, reduces OA pain, and lowers self-reported disability. This study is to analyze and understand the effect of perturbation training and dynamic resistance exercise training on muscle strength and knee extension range of motion in grade II knee osteoarthritis. Grade II Osteoarthritis knee patient was recruited for this study. 20 sessions of perturbation training with dynamic resistance exercises for the affected knee joint for 30 minutes, session with 5 sessions per week were given. Pre and Post Intervention values of muscle strength of 1 Repetition Maximum for knee extensor and knee extension range of motion was taken and analyzed. This case study results had shown significant improvement in the outcome of muscle strength in 10 RM and knee extension ROM after the combined intervention of perturbation training and resistance exercise for Grade II OA Knee Patients. Thus this study may be concluded that there was a significant improvement in knee extensor muscle strength (1 RM) in the affected knee joint in a patient with grade II knee osteoarthritis after combined intervention perturbation training and dynamic resistance exercises.
La política pública de gestión territorial, comercial, social, ambiental, urbanístico del gad del cantón arenillas en su parte administrativa
Authors: Vilela Pincay Wilson Exson , Rivera Torres Elkin Paul 
Published: July 2024

Este articulo tiene como objetivo, La política pública de gestión territorial, comercial, social, ambiental, urbanístico del GAD del cantón arenillas en su parte administrativa la metodología responde a una investigación descriptiva de tipo de revisión bibliográfica con enfoque cualitativo, sistematizada mediante los métodos histórico lógico, análisis documental, los hallazgos evidencian la contextualización de esta dimensión develando su carácter multicultural no obstante el análisis de los documentos observan la existencias de asimetrías entre el discurso, social, ambiental, urbanístico, plurinacional y administrativa en el quehacer histórico a la diversidad de culturas que se asentaron en el cantón.
Perancangan Purwarupa Mobile App Pemanfaatan Food Waste untuk Mendorong Ekonomi Sirkular sebagai Solusi Pangan
Authors: Shirley Stephanie Elizabeth 
Published: July 2024

Penumpukan food waste di Indonesia menjadi masalah krusial dengan dampak negatif yang signifikan. Fenomena food waste ini disebabkan oleh pemborosan makanan dan pengelolaan sampah yang tidak optimal. Dampaknya meliputi degradasi lingkungan, kerugian ekonomi, memperparah kelaparan, dan mengancam ketahanan pangan. Oleh karena itu, dalam penelitian ini akan dirancang model bisnis dan purwarupa mobile app pemanfaatan food waste sebagai solusi pengelolaan food waste yang terintegrasi dan efektif. Aplikasi ini diharapkan dapat mempermudah akses masyarakat terhadap makanan berlebih dan daur ulang food waste, sehingga meningkatkan pengelolaan food waste dan menciptakan ekonomi sirkular di Indonesia.
Terdapat 4 tahapan proses dasar untuk mencapai kesuksesan perancangan purwarupa ini. Tahapan tersebut meliputi identifikasi masalah, pengumpulan data dengan metode studi literatur, perancangan User Interface (UI) untuk menentukan aplikasi referensi dan konsep purwarupa, dan hasil perancangan yang merupakan hasil final dari purwarupa yang telah dibuat.
Hasil penelitian membahas tentang pembuatan ide bisnis aplikasi bernama FOODCYCLE. Perancangan purwarupa ini didasarkan pada penelitian terdahulu yang menganalisis kelayakan aplikasi food waste yang cukup serupa. Di mana penelitian tersebut menunjukkan adanya hasil yang positif dari aplikasi food waste dalam meningkatkan behavioral intention pengguna melalui model TAM (Technology Acceptance Model). Hal ini dipengaruhi oleh perceived ease of use dan perceived usefulness. Penyusunan konsep pada bagian ini juga mengacu pada aplikasi referensi. Hasil akhir dari penelitian ini terbagi menjadi karya utama yang merupakan purwarupa mobile app dalam bentuk UI dan karya pendukung berupa rancangan desain media sosial, banner, dan brosur mobile app
Implementation of Condition Monitoring and Predictive Maintenance for Building Sustainability
Authors: Ahmad Subri Ahmad Danial , Suleiman Mohd Zailan 
Published: July 2024

This research explores the role of Condition Monitoring and Predictive Maintenance (CPM) in improving building sustainability. CPM is a technique that uses advanced sensors and data analysis to anticipate and prevent equipment failure, ensuring the system operates smoothly and efficiently. Through real examples, CPM is of benefit, for energy savings, reduced maintenance costs and extending the lifespan of building components. The research methodology outlines the systematic approach mix-method by applying survey questionnaires to the stakeholders in Malaysia and case studies in selected areas. The findings revealed that CPM can lead to significant sustainability gains in the built environment by optimizing resource use and reducing waste. Challenges encountered such as start-up costs and the need for skilled personnel were also discussed. The results also offer recommendations for successful use of CPM. In overall, this research revealed that CPM is a valuable tool for making buildings more sustainable.
PUNISHMENT TELEOLOGY IN INTERNATIONAL CRIMINAL JUSTICE: INSIGHTS FROM THE ICC'S JURISPRUDENCE
Authors: Mazurek Maria 
Published: July 2024

The following study explores the issue of rationales for international criminal punishment by studying the treatment this question has received in the jurisprudence of the International Criminal Court. The aim is to help construct a normative, theoretical foundation for the practice of international criminal tribunals. First, it looks into all seven ICC sentencing judgements to deconstruct the parts in which the judges discuss why the court punishes. Upon a comparative analysis of the teleological pronouncements, the paper identifies three patterns in the ICC’s teleological discourse. These include: the court’s unfounded import of domestic punishment rationales, fusion of different objectives and rhetorical, performative language used to justify punishment. Building on these findings and literature on the expressivism of punishment, I put forward the claim that the ICC judges’ discourse on penal rationales reveals an expressive function of punishment at play. Finally, the paper discusses how the ICC uses this expressivist practice in its jurisprudence to build a narrative of legalism and situate itself in the wider project of international justice. By implication, this legalism narrative is then seen as the court’s tool in fighting against its legitimacy crisis.
THE DIRECTIVE ON CORPORATE SUSTAINABILITY DUE DILIGENCE: SUCCESS OR A FAILURE?
Authors: Bakhtina Krystyna 
Published: July 2024

Formally endorsed by the European Parliament and the Council of the European Union in spring 2024, the Directive on Corporate Sustainability Due Diligence (CSDDD) is going to become an EU legally binding instrument. The present article demonstrates the main features of this legislation and highlights that despite its strong initial ambitions, the final text of the Directive has considerable weaknesses and there are serious doubts on whether the Directive will indeed achieve its goal of fostering a respect for human rights and environmental protection among the companies’ operations and across their global value chains.
ANALISIS PARTISIPASI LAKI -LAKI DALAM PROGRAM KELUARGA BERENCANA DI INDONESIA: SEBUAH PENDEKATAN THEORY OF PLANNED BEHAVIOUR
Authors: Rochimah Haris Annisari Indah Nur , Priastuty Chairunnisa Widya , Wicaksono Jefri 
Published: July 2024

Program Keluarga Berencana (KB) adalah inisiatif pemerintah Indonesia untuk mengatur pertumbuhan penduduk dan membentuk keluarga yang berkualitas. Meskipun diakui secara internasional sebagai program yang berhasil menurunkan angka kelahiran, KB seringkali dianggap sebagai tanggung jawab perempuan, sehingga partisipasi laki-laki rendah. Studi ini memfokuskan pada data subjek penelitian sebelumnya yakni laki- laki remaja dewasa, yang mayoritas belum menikah. Penelitian ini ingin melihat partisipasi laki-laki terutama remaja dewasa dari sudut pandang Theory of Planned Behavior yang melihat sikap, norma subjektif dan kontrol perilaku mereka terhadap partisipasi mereka pada program KB di Indonesia. Studi ini menggunakan pendekatan kualitatif dengan menganalisis studi pustaka dan literatur terkait penelitian tentang KB, remaja laki-laki dan faktor-faktor yang mempengaruhi perilaku mereka.Temuan dari penelitian ini adalah pengaruh keluarga, tenaga kesehatan, teman, media, dan lingkungan tinggal berperan dalam membentuk sikap positif terhadap program KB. Faktor psikologis, seperti kekhawatiran akan impotensi, dan stigma sosial juga mempengaruhi sikap dan partisipasi laki-laki. Dukungan tokoh agama juga memainkan peran penting dalam membentuk norma subjektif. Peningkatan pengetahuan, informasi, edukasi, serta kampanye media massa dapat mengubah sikap dan meningkatkan partisipasi laki-laki dalam KB. Hasil penelitian ini dapat membantu merumuskan strategi dan program yang lebih efektif untuk meningkatkan peran laki-laki dalam program KB di Indonesia.
Analyses of Johannes Kepler’s Sunspot Drawings in 1607: A Revised Scenario for the Solar Cycles in the Early 17th Century
Authors: Hayakawa Hisashi , Murata Koji , Teague E. Thomas H. , Bechet Sabrina , Sôma Mitsuru 
Published: July 2024

Abstract
Telescopic sunspot observations began in 1610 and captured subsequent solar cycles. In combination with proxy reconstructions on an annual scale, these data sets indicate a gradual transition between regular solar cycles and the Maunder Minimum. The telescopic sunspot observations missed the beginning of the first telescopic solar cycle (Solar Cycle −13), leaving room for considerable uncertainty as to its temporal evolution. Before these early telescopic observations, however, Kepler made solar observations using camerae obscurae and recorded a sunspot group in three solar drawings in 1607. Here, we make use of Kepler’s sunspot drawings and descriptive texts to identify his observational sites and time stamps. We have deprojected his sunspot drawings and compared the reported positions with our calculations of the inclination of the solar equator as seen from these sites at that time. These results locate the reported sunspot group near the solar equator eastward from the central meridian. This contrasts with telescopic sunspot drawings from the 1610s that show sunspot groups in the higher heliographic latitudes. Therefore, what Kepler saw was probably a sunspot group from Solar Cycle −14, rather than one from Solar Cycle −13. These records allow us to place the beginning of Solar Cycle −13 between 1607 and 1610. In comparison with the 14C-based solar-cycle reconstructions, our result supports regular solar-cycle durations around the 1610s, rather than any suggested extreme extensions of the solar-cycle duration(s) around the 1610s.