bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGEMBANGAN LEMBAR KERJA PESERTA DIDIK (LKPD) KINEMATIKA GERAK LURUS PADA SMA MENGGUNAKAN LEARNING CYCLE 7E UNTUK MELATIHKAN KETERAMPILAN BERPIKIR KRITIS SISWA
Authors: Fajria Indah , Putri Desy Hanisa , Setiawan Iwan 
Published: July 2024

ABSTRAK

Penelitian ini merupakan jenis penelitian dan pengembangan (R&D) yang bertujuan untuk menghasilkan produk, mendeskripsikan kelayakan, mendeskripsikan karakteristik dan mengetahui respons siswa terhadap LKPD kinematika gerak lurus menggunakan Learning Cycle 7E untuk melatihkan keterampilan berpikir kritis siswa SMA. Penelitian ini menggunakan model pengembangan 4D yang di modifikasi menjadi 3D yaitu define, design, dan development. Pada tahap define terdiri dari studi literatur, analisis observasi awal dan analisis questioner awal kebutuhan guru dan siswa. Tahap design terdiri rancangan produk LKPD dan tahap development terdiri validasi ahli, revisi berdasarkan saran/masukan dari validasi ahli dan melakukan uji keterbacaan produk kepada siswa. Hasil validasi ahli yang telah dilakukan menunjukkan bahwa LKPD yang dikembangkan dalam kategori sangat layak yaitu dengan nilai 84,44 % dan respons siswa pada kategori sangat baik yaitu dengan nilai 91,11%. Karakteristik dari LKPD ini terdiri dari 5 karakteristik yaitu self instructional, self contained, stand alone, adaptif, and user friendly.

Kata kunci: Penelitian dan pengembangan (R&D), LKPD, Learning Cycle 7E, dan Keterampilan berpikir kritis

ABSTRACT

This research is a type research and development (R&D) aimed at producing products, describe worthiness, describe characteristics and determine student responses to LKPD kinematics straight motion using the learning cycle 7E to improve senior high school students critical thinking skills. This research uses a 4D development model that is modified into 3D, namely define, design, and development. At the define stage consists of a literature study, an early observational analysis and questioner an early analysis of the needs and students. The design phase consists of expert validation, a revision based on the advice/input from expert validation and conducting the study of product reading to students. The results of expert validation that have been carried out show that the LKPD developed in the very feasible category is with a score of 84,44% and student responses in the very good category, namely with a score of 91,11%. The characteristics of this LKPD consist of 5 characteristics namely self instructional, self contained, stand alone, adaptive, and user friendly.
Keywords: Research and development, LKPD, Learning Cycle 7E and Critical Thinking Skills.
PENGARUH MEDIA TUMBUH DAN INTENSITAS CAHAYA TERHADAP PERTUMBUHAN BIBIT GAHARU (Grynops versteegii) ASAL KEKAIT PUNCANG
Authors: Nur Zarkasi , Wangiyana I Gde Adi Suryawan 
Published: July 2024

Pembibitan G. versteegii merupakan faktor esensial dalam mendukung budidaya gaharu di Pulau Lombok. Penelitian ini bertujuan untuk mengetahui pengaruh komposisi media dan intensitas cahaya terhadap pertumbuhan bibit G. versteegii. Penelitian menggunakan Rancangan Acak Lengkap Faktorial dengan dua faktor yaitu Media Semai (M1: tanah:Sekam = 2:1; M2: tanah:sekam = 1:2; M3: tanah:sekam = 1:1) dan Intensitas Cahaya (I1: intensitas cahaya 50%; I2: Intensitas Cahaya 25%). Terdapat 5 Penelitian ini yaitu: persiapan lahan pembibitan, persiapan media tumbuh, penanaman bibit, pemeliharaan bibit, dan pengamatan pertumbuhan bibit. Data parameter perumbuhan tinggi bibit dan jumlah daun bibit di analisis dengan Analisis of Varian (ANVOA) dan uji Beda Nyata Jujur (BNJ) pada taraf α = 0,05. Selain itu dilakukan pula analisis standard error dengan menggunakan program Co-Stat for windows. Hasil ANOVA menunjukkan bahwa faktor media semai dan faktor intensitas cahaya berpengaruh signifikan terhadap tinggi bibit dan jumlah daun bibit. Akan tetapi tidak terdapat interaksi antarfaktor. Tinggi batang bibit G. versteegii pada medium pertumbuhan berbeda dapat diurutkan mulai dari yang terbesar ke terkecil yaitu: M1, M3, dan M2. Sementara intensitas cahaya I1 memberikan pengaruh tinggi bibit lebih besar dibandingkan I2. Rerata jumlah daun pada bibit juga menunjukkan pola yang sama dengan data tinggi bibit. Dapat disimpulkan bahwa faktor yang mendukung pertumbuhan bibit G. versteegii yang optimal adalah medium dengan komposisi tanah:sekam = 2:1 dan intensitas cahaya 50%.
PERSEPSI MASYARAKAT TERHADAP PENGELOLAAN HUTAN KEMASYARAKATAN LEMBAH SEMPAGER PADA BLOK 3 DESA GUNUNG MALANG KECAMATAN PRINGGABAYA KABUPATEN LOMBOK TIMUR
Authors: Andini Risma Ayu , Masrilurrahman L L Suhirsan 
Published: July 2024

Persepsi merupakan proses untuk memahami lingkungan yang meliputi objek dan simbol. Penelitian ini bertujuan untuk mengetahui persepsi masyarakat terhadap pengelolaan hutan kemasyarakatan (Hkm) Lembah Sempager pada blok 3. Metode yang digunakan dalam penelitian ini adalah metode random sampling. Data primer di dapatkan melalui teknik observasi, kuisoner, wawancara dan dokumentasi dengan menggunakan kuisioner 20 orang. Dalam penelitian ini data dianalisis menggunakan skala likert. Pengukuran komponen penilaian pada skala likert yaitu mencakup rentang nilai 5 di artikan sangat setuju, rentang nilai 4 ≤ 4,5 diartikan setuju, rentang 3 ≤ 3,5 ragu-ragu, rentang 2 ≤ 2,5 diartikan tidak setuju, dan rentang 1 diartikan sangat tidak setuju. Berdasarkan hasil penelitian mengenai persepsi masyarakat terhadap pengelolaan hutan kemasyarakatan lembah sempager pada blok 3 yaitu mengenai persepsi masyarakat terhadap perencanaan HKm mendapatkan nilai akhir yaitu (4,5), persepsi masyarakat terhadap pengorganisasian HKm mendapatkan nilai akhir yaitu (4,4), persepsi masyarakat terhadap pelaksanaan HKm mendapatkan nilai akhir yaitu (4,6) dan persepsi masyarakat terhadap pengawasan HKm mendapatkan nilai akhir yaitu (4,4). Dalam hal ini masyarakat pada blok 3 mendapatkan dampak yang baik terutama dari segi ekonomi.
Adjustable parameters-based control strategy for VSG-type grid forming converters considering grid strength
Authors: Hu Xuekai , Li Zifan , Shu Zhipeng , Wang Yaqin 
Published: July 2024

IntroductionGrid-forming control has received increasing attention for being an effective solution to cope with low-inertia and weak damping systems. Owing to the basic characteristics of transient voltage regulation, inertia support and primary frequency regulation (PFR), virtual synchronous generator (VSG) is the most promising candidate of grid-forming control scheme. The damping characteristic plays a significant role in stabilizing when the system is disturbed. However, the traditional approaches for damping emulation pose a number of problems, such as the introduction of phase-locked loop (PLL) that may lead to stability issues, or the blurring of the functional distinction between damping characteristic and primary frequency regulation. Moreover, the grid strength affects the operational characteristics of the converters.MethodsBased on the background of these issues, firstly, an effective transient damping power strategy is proposed in this paper. In contrast to conventional damping approaches, the proposed scheme provides a positive damping during transient period that suppresses the fluctuation of active power, and has no impact on the steady-state frequency droop characteristic. Ulteriorly, based on small-signal models and classical control theory, an parameters adjustment strategy for both active and reactive power control is proposed to considerably enhance the adaptability of the converter to the variations in grid strength.Results and DiscussionThe results obtained from PSCAD/EMTDC and hardware-in-the-loop (HIL) platform verify that proposed control strategy exhibits excellent transient damping effect, the decoupling characteristic between fixed damping coefficient and PFR coefficient, and performs well across a broad spectrum of grid strengths.
Working characteristic research on the mechanical stable platform of the automatic vertical drilling system
Authors: Chai Lin , Sun Qiang , Liu Baolin , Tang Feng 
Published: July 2024

As a novel technology, the mechanical stable platform can effectively improve the temperature resistance of the automatic vertical drilling system, but its working characteristics are still not yet clear. In this paper, theoretical mechanics is introduced to establish the critical deviation angle model, in order to evaluate the sensitivity of the mechanical stable platform to well deviation. Multi-body dynamics simulation is applied to mutually verify the models and further analyze the effect of vibration. The results show that the critical deviation angle is not only affected by the platform design parameters, but also by the system speed and external vibration. When the system angular velocity is less than the critical angular velocityωc(3.76 rad/s), the critical deviation angleαC′gradually decreases with the decreasing angular velocity until it approaches the extreme deviation angleαl(5.1°). The critical deviation angle is jointly affected by the amplitude A and frequency B of torsional vibration. When A&gt;500°/s and B &gt; 8 Hz, its variation range is between theαl(5.1°) and the critical deviation angleαc(7.03°). The critical deviation angle is jointly affected by the amplitude E and frequency F of axial vibration, with its value always greater thanαc, but very small range of variation (0.2°). Torsional vibration plays a dominant role in torsional-axial coupled vibration, and the additional effect of axial vibration is relatively small. The results obtained herein are significant for further understanding and improvement of the performance of the mechanical vertical drilling system.
Association between systemic inflammatory response index and bone turnover markers in Chinese patients with osteoporotic fractures: a retrospective cross-sectional study
Authors: Zhou Peng , Lu Ke , Li Chong , Xu Min-zhe , Ye Yao-wei , Shan Hui-qiang , Yin Yi 
Published: July 2024

BackgroundThe systemic inflammatory response index (SIRI) is a novel composite biomarker of inflammation. However, there is limited information on its use in the context of osteoporotic fractures. Hence, this study aimed to investigate the association between baseline SIRI values and bone turnover markers (BTMs) in Chinese patients diagnosed with osteoporotic fractures (OPFs), to offer a more precise method for assessing bone health and inflammation in clinical settings.MethodsA retrospective cross-sectional study was conducted on 3,558 hospitalized patients with OPFs who required surgery or hospitalization at the First People’s Hospital of Kunshan City from January 2017 to July 2022. Baseline measurements of SIRI, β-CTX (beta-C-terminal telopeptide of type I collagen), and P1NP (procollagen type I N-terminal propeptide) were obtained. The analyses were adjusted for variables, including age, sex, body mass index (BMI), and other initial laboratory and clinical findings. Furthermore, multivariable logistic regression, smooth curve fitting, and threshold analysis were also performed.ResultsThe results revealed a negative correlation between baseline SIRI values and both β-CTX and P1NP levels. After adjusting for covariates in the regression analysis, each unit increase in SIRI was found to be inked to a reduction of 0.04 (β = −0.04; 95% confidence interval [CI], −0.05 to −0.03; with p-value &lt;0.001) in β-CTX levels and a decrease of 3.77 (β = 3.77; 95% CI, 5.07 to 2.47; with p-value &lt;0.001) in P1NP levels. Furthermore, a curvilinear relationship and threshold effect were also identified. Turning points were identified at SIRI values of 1.41 and 1.63 on the adjusted smooth curve.ConclusionThe results showed a negative correlation between the baseline SIRI value and β-CTX level, as well as the level of P1NP. This suggests a possible link between the systemic inflammatory response and reduced bone metabolism. If these findings are verified, SIRI has the potential to function as a predictive indicator for BTMs. Nevertheless, additional research is necessary to verify these findings.
Bamboo fiber improves piglet growth performance by regulating the microbial composition of lactating sows and their offspring piglets
Authors: Dai Fawen , Lin Tao , Jin Muqu , Huang Xia , Wang Lu , Ma Jing , Yu Hang , Fan Xianlin , Nong Xiang , Zuo Jianjun 
Published: July 2024

IntroductionFeeding bamboo powder is a kind of fiber raw material mainly composed of insoluble dietary fiber (IDF). In this study, IDF-based rice husk meal and feeding bamboo powder were used to compare the effects of bamboo fiber on fecal microflora and the performance of lactating sows and their offspring piglets.MethodsThirty healthy crossbred gilts (Yorkshire × Landrace) at day 105 of gestation were randomly allocated into three groups: CON, TRE1 supplemented with 2% BBF1 (feeding bamboo powder), and TRE2 supplemented with 2% BBF2 (99% feeding bamboo powder +1% bamboo fiber polymer material). The reproductive performance, serum indexes, and fecal microbiota of sows and piglets were analyzed. The results showed that, compared with CON, the average feed intake of sows in TRE1 during the second week of lactation was significantly increased by 21.96% (p &lt; 0.05), the average daily gain (ADG) per litter in TRE1 on 11–21 days and 3–21 days of lactation was significantly increased by 50.68 and 31.61%, respectively (p &lt; 0.05), and the serum triglyceride content of sows in TRE1 on the 21st day of lactation was significantly increased (p &lt; 0.05). The 16S rRNA analysis showed that dietary bamboo fiber significantly increased the fecal microbial richness index Ace, Chao, and Sobs of sows (p &lt; 0.05) and tended to increase the Sobs index of suckling piglets on day 21 (p &lt; 0.10). Compared with CON, BBF1 supplementation significantly decreased the abundance of Christensenellaceae_R-7_group in feces of sows on days 7 and 21 after delivery (p &lt; 0.05), while BBF2 decreased the genera Christensenellaceae_R-7_group on days 7 (p &lt; 0.10) and 21 (p &lt; 0.05) after delivery. Spearman correlation analysis showed that the abundance of Phascolarctobacterium in the feces of piglets on the 21st day after delivery was significantly positively correlated with diarrhea rate and significantly negatively correlated with ADG per litter, day 21 litter weight, and 3- to 21-day survival rate. In contrast, Christensenellaceae_R-7_group was significantly negatively correlated with diarrhea rate and positively correlated with ADG per litter.DiscussionThese results indicated that maternal BBF1 supplementation improved the litter weight gain of suckling piglets, which was associated with the improvement of diversity and structure of the fecal microbiota in the piglets.
Relapse treatment with low-dose steroids in steroid-sensitive minimal change disease
Authors: Martin Capon Irene , Gutierrez Eduardo , Huerta Ana , Viera Elizabeth , Alvarez Nadal Marta , Fernández-Lucas Milagros , Villacorta Javier 
Published: July 2024

BackgroundThe treatment of minimal change disease (MCD) consists of a high dose of steroids for several months, implying significant drug toxicity. Nevertheless, relapses of steroid-sensitive MCD usually respond to lower doses of steroids.MethodsThe objective of this study was to analyze whether a low dose of steroids (LDS) is effective for the treatment of MCD relapses. Since 2018, new relapses of steroid-sensitive adult patients with MCD in three Spanish centers have been treated with LDS. The cumulative dose of steroids, the time to remission, and the relapse-free time were compared between relapses treated with LDS and previous relapses of the same patients treated with a standard dose of steroids (SDS).ResultsA total of 51 relapses in 31 patients were treated with LDS and compared with 48 historical relapses of the same patients treated with SDS. The mean doses of prednisone adjusted by weight for the initial treatment were 0.45 mg/kg (0.40–0.51 mg/kg) in the relapses treated with LDS and 0.88 mg/kg (0.81–1.00 mg/kg) in those treated with SDS. The mean cumulative doses of prednisone in LDS- and SDS-treated relapses were 1,191 mg (801–1,890 mg) and 3,700 mg (2,755–5,800 mg), respectively. The duration of treatment was 63 days (42–117 days) in the LDS group and was 140 days (65–195 days) in the SDS group. All patients achieved complete remission within 1 month after steroid therapy in both groups. The times to remission of the LDS and SDS groups were 19.10 ± 12.80 and 18.93 ± 12.98 days, respectively (p = 0.95).ConclusionAmong the steroid-sensitive patients with MCD, relapse therapy with LDS (0.5 mg/kg) appears effective and allows minimization of the steroid cumulative dose.
Clinical validation of commercial deep-learning based auto-segmentation models for organs at risk in the head and neck region: a single institution study
Authors: Johnson Casey L. , Press Robert H. , Simone Charles B. , Shen Brian , Tsai Pingfang , Hu Lei , Yu Francis , Apinorasethkul Chavanon , Ackerman Christopher , Zhai Huifang , Lin Haibo , Huang Sheng 
Published: July 2024

PurposeTo evaluate organ at risk (OAR) auto-segmentation in the head and neck region of computed tomography images using two different commercially available deep-learning-based auto-segmentation (DLAS) tools in a single institutional clinical applications.MethodsTwenty-two OARs were manually contoured by clinicians according to published guidelines on planning computed tomography (pCT) images for 40 clinical head and neck cancer (HNC) cases. Automatic contours were generated for each patient using two deep-learning-based auto-segmentation models—Manteia AccuContour and MIM ProtégéAI. The accuracy and integrity of autocontours (ACs) were then compared to expert contours (ECs) using the Sørensen-Dice similarity coefficient (DSC) and Mean Distance (MD) metrics.ResultsACs were generated for 22 OARs using AccuContour and 17 OARs using ProtégéAI with average contour generation time of 1 min/patient and 5 min/patient respectively. EC and AC agreement was highest for the mandible (DSC 0.90 ± 0.16) and (DSC 0.91 ± 0.03), and lowest for the chiasm (DSC 0.28 ± 0.14) and (DSC 0.30 ± 0.14) for AccuContour and ProtégéAI respectively. Using AccuContour, the average MD was&lt;1mm for 10 of the 22 OARs contoured, 1-2mm for 6 OARs, and 2-3mm for 6 OARs. For ProtégéAI, the average mean distance was&lt;1mm for 8 out of 17 OARs, 1-2mm for 6 OARs, and 2-3mm for 3 OARs.ConclusionsBoth DLAS programs were proven to be valuable tools to significantly reduce the time required to generate large amounts of OAR contours in the head and neck region, even though manual editing of ACs is likely needed prior to implementation into treatment planning. The DSCs and MDs achieved were similar to those reported in other studies that evaluated various other DLAS solutions. Still, small volume structures with nonideal contrast in CT images, such as nerves, are very challenging and will require additional solutions to achieve sufficient results.
Clinical and pathological characteristics of cervical clear cell carcinoma in patients not exposed to diethylstilbestrol: a comprehensive analysis of 49 cases
Authors: Zeng Jing , Jiang Wei , Li Kemin , Zhang Mengpei , Chen Jinghong , Duan Yuanqiong , Li Qingli , Yin Rutie 
Published: July 2024

PurposeThis study aimed to investigate the clinical and pathological characteristics, treatment strategies, and prognosis of cervical clear cell carcinoma (CCCC) in patients not exposed to diethylstilbestrol in uteroMethodsThe patients diagnosed with CCCC at West China Second University Hospital of Sichuan University between January 2011 and Jun 2023 were enrolled for this retrospective study. The clinical characteristics and information on treatment and follow-up were collected. The Kaplan–Meier method and Cox regression analysis were performed to identify the relative variables for predicting progression-free survival (PFS) and overall survival (OS).ResultsOf the 49 patients included, the Federation International of Gynecology and Obstetrics (FIGO) (2018) stage distribution was 37 (75.5%) stage I, 6 (12.2%) stage II, and 6 (12.2%) stage III. The median follow-up interval was 24.1 months. Six (12.2%) patients had a recurrence, and five (10.2%) patients died. The 5-year PFS rate was 86.8%, and the 5-year OS rate was 88.2%. No recurrence or death was detected in two patients who successfully completed fertility-preserving treatment and seven patients who underwent surgery to preserve ovaries. Two patients became pregnant, giving birth to two babies. The univariate analysis showed that FIGO stage, Pelvic lymph node (PLN) metastasis, lymph vascular space invasion, and depth of stromal invasion (P &lt; 0.05) were significantly associated with PFS and OS. However, no significant prognostic factors were identified in the multivariate analysis.ConclusionOvary-preserving treatment and fertility-preserving surgery are safe and feasible in early-stage CCCC. Surveillance other than adjuvant treatment may be a better choice for early-stage CCCC without any pathological risk factors. More targeted therapies and immunotherapy should be pursued in future studies.
Comparisons of infection events associated with tumor necrosis factor inhibitors in patients with inflammatory arthritis: A systematic review and network meta-analysis
Authors: Jiang Ziwei , Zou Yue , Li Guangyao , Zhao Sixuan , Zhang Wei 
Published: July 2024

Objective: To compare the risk of infection in inflammatory arthritis patients treated with tumor necrosis factor (TNF) inhibitors.Methods: PubMed, Embase, and the Cochrane Library were systematically searched from inception to 28 December 2023 for randomized controlled trials (RCTs) assessing TNF inhibitors and reporting infections. Subsequently, pairwise and network meta-analyses were conducted to determine odds ratios (ORs) and the corresponding 95% confidence intervals (CIs).Results: A total of 61 RCTs involving 20,458 patients were included. Pairwise meta-analysis revealed that certolizumab pegol was significantly associated with an increased risk of serious infection compared to placebo (OR:2.28, 95% CI: 1.13–4.62). Both adalimumab and certolizumab pegol were also significantly associated with an increased risk of any infection compared to placebo (OR:1.18, 95% CI: 1.06 to 1.30 and OR:1.40, 95% CI: 1.11 to 1.76, respectively). Moreover, a network meta-analysis indicated that certolizumab pegol and infliximab were associated with a higher risk of serious infection compared to other TNF inhibitors. In the cumulative ranking of any infection risk, certolizumab pegol had the highest risk compared with others. TNF inhibitors increased the risk of tuberculosis but not that of herpes zoster.Conclusion: Available evidence indicates etanercept and golimumab are likely associated with a lower risk of infection compared to other TNF inhibitors in inflammatory arthritis. For patients at a heightened risk of infection, prioritizing the use of etanercept and golimumab may be advisable to minimize patient risk.Systematic Review Registration: identifier CRD42022316577