bluuebunny/crossref_metadata_2025_split huggingface dataset:
Immunosuppression and monocyte subsets
Authors: Rogacev Kyrill S. , Zawada Adam M. , Hundsdorfer Johanna , Achenbach Marina , Held Gerhard , Fliser Danilo , Heine Gunnar H. 
Published: October 2014

Abstract

Background
Monocytes are critical in innate immunity and transplantation. Three monocyte subsets exist, CD14++CD16−, CD14++CD16+ and CD14+CD16++ monocytes; cell counts of CD14++CD16+ and CD14+CD16++ monocytes are increased in pre-transplant chronic kidney disease. Interestingly, the effect of immunosuppressants on monocyte heterogeneity has not been well studied.

Methods
The impact of immunosuppressants on monocyte subsets was studied: (i) in 152 kidney transplant (KTx) recipients to characterize subset distribution in the steady state, (ii) in patients after autologous (n = 10) versus allogenic (n = 9) haematopoietic stem cell transplantation (HSCT) to analyse monocyte subset development and (iii) in an in vitro model to compare the effect of immunosuppressants on monocyte subset biology.

Results
In KTx, steroid intake was associated with higher total, CD14++CD16− and CD14++CD16+ monocyte counts, but fewer CD14+CD16++ monocytes, whereas intake of mycophenolate, calcineurin inhibitors (CNI) and mammalian target of rapamycin inhibitors (mTORI) did not affect monocyte (subset) counts. In linear regression analysis, only steroid intake was a significant determinant of monocyte (subset) counts: total monocytes (β = 0.331; P &lt; 0.001), CD14++CD16− monocytes (β = 0.374; P &lt; 0.001), CD14++CD16+ monocytes (β = 0.221; P = 0.010) and CD14+CD16++ monocytes (β = −0.169; P = 0.049). After HSCT, CD14++CD16− monocytes were the first to arise, followed by CD14++CD16+ and later by CD14+CD16++ monocytes. Monocyte subset distribution did not differ significantly in patients after allogenic compared with autologous transplantation. CNI, mycophenolate and methotrexate did not influence monocyte subset development, but modified surface receptor expression (CCR2, HLA-DR, ENG, TEK and TLR4) in allogenic HSCT.

Conclusion
Chronic low-dose steroids are associated with monocytosis and higher counts of CD14++CD16− and of proinflammatory CD14++CD16+ monocytes.
Boosting facility managers’ personal and work outcomes through job design
Authors: Yean Yng Ling Florence , Toh Weiyan 
Published: October 2014

Purpose– This study aims to identify the job characteristics that would boost the personal and work outcomes (e.g. job satisfaction, internal motivation and output quality) of facility managers (FMs) in Singapore based on the Job Characteristics Theory.Design/methodology/approach– The research method is a survey method, and data were collected using a structured questionnaire from 34 FMs through electronic mail and by post.Findings– Usingt-test of the mean, 23 out of the 39 identified job characteristics are found to be significantly present in FMs’ jobs. Pearson’s correlation analysis revealed that the job characteristics that are significantly correlated with personal and work outcomes of FMs include those that use a variety of skills, in which task identity is present, task is significant, allow autonomy, provide feedback and meet FMs’ growth needs.Research limitations/implications– The Job Characteristics Theory is found to be applicable to FMs’ jobs, but this needs to be generalized carefully because of the relatively small sample size.Practical implications– It is recommended that the significant job characteristics that are identified in this study be designed and incorporated into FMs’ jobs. These include setting up teams where members play their parts well; a reward system when a job is done well; a career path with ample opportunities for promotion; and communication channels that are clear and precise.Originality/value– Important job characteristics that could boost FMs’ job satisfaction, internal motivation and quality of work are identified. In addition, job characteristics that could reduce their likelihood of leaving the profession are also uncovered. These job characteristics should be designed into FMs’ jobs, so that firms have high performing and motivated FMs.
Reflecting on future research concerning the added value of FM
Authors: Anker Jensen Per , J.M. van der Voordt Theo , Coenen Christian , Sarasoja Anna-Liisa 
Published: October 2014

Purpose– This paper aims to summarize recent research findings and reflections onThe Added Value of Facilities Management(FM) and to outline perspectives for future research and development of the added value of FM.Design/methodology/approach– The article is based on reflections on contributions to the recently published book “The Added Value of Facilities Management” and related future studies, as well as further exploration of five main themes.Findings– Added value is expected to be central in the future development of FM, which is confirmed by recent foresight studies. There is a need for a better understanding of alignment between FM and core business, performance measurement methods and how models such as the FM Value Map can be of value to the involved stakeholders. Corporate social responsibility (CSR), sustainability and branding have great potential to add value and to elevate FM to become a strategic partner with corporate top management. Management of stakeholders’ perception of value and relationships are essential aspects as well and need further attention.Research limitations/implications– The article is based on the conclusions of several studies that aimed to explore items for further research, on the ideas of all co-authors of “The Added Value of Facilities Management” anthology and on further exploration of five main themes, and not on an extensive review of recommendations for further research to be found in a huge number of research reports.Practical implications– The findings and ideas for further research on the added value of FM deliver input to further professionalization of FM.Originality/value– This paper provides important input to the future research agenda on the added value of FM and sheds new light on five particular research topics.
Meta-measures for technology and environment
Authors: Young Phillips Fred 
Published: October 2014

Purpose– The purpose of this paper is to examine the question: What shall we measure? and offers preliminary answers. Data for innovation management and policy must be valid, reliable, relevant and actionable.Design and approach– The paper examines trends within finance, environment and institutions and society, all with regard to innovation and technology. It examines how these trends interact with each other and with measurement of innovation and socio-technical change.Findings– In the future, measurement for innovation policy must occur in markedly different ways – and on quite different scales – than is currently the practice. The paper concludes with a future-oriented list of items to be measured, with preliminary guidelines on how to organize to measure them.Research limitations/implications– Foresight researchers must put new emphasis on measurement.Practical implications– Local and national statistical agencies will have to measure new indicators and organize differently to measure them.Social implications– Voters may be eager to embrace principles and goals, though they fail to find excitement in the more tedious issues of measurement. It is incumbent on us to pay more attention to measurement, to resist governments’ and lobbyists’ efforts to introduce special-interest bias into public statistics, and to carry the story to the public of the importance of measurement. Much of the policy change that is now needed is needed because of past and current harmful human behaviors. Nicholas Sarkozy (Press 2011) concisely stated the rationale for this paper: “We will not change our behavior unless we change the ways we measure”.Originality/value– This concept paper goes beyond other indexes and proposals to identify new phenomena that must be measured. In contrast to other works which are oriented to measurement-push (toward policy), the present paper makes bold assertions about the trends needing to be addressed by policy, then proposes measurement based on policy-pull. It argues against premature worldwide statistical standards, and for Popperian “multiple engineering experiments”.The USA must “get back into the future business” – President Bill Clinton, at the Milken Institute Global Conference 2012.
“After 300 meters turn right” – the future of Russia’s GLONASS and the development of global satellite navigation systems
Authors: B. Bokov Mikhail , Edelkina Anastasia , Klubova Marina , Thurner Thomas , P. Velikanova Natalia , Vishnevskiy Konstantin 
Published: October 2014

Purpose
– Global navigation satellite systems (GNSS) were designed to determine the exact location of objects on land, water and air for military purposes. With the opening of the satellite signal for civilian use, the technology created business opportunities for various applications. Today, satellite positioning technology is used by transporters, carriers, motorists, surveyors, builders, foresters, etc. through a wide array of devices like mobile phones or multimedia devices with built-in receiver modules.

Design/methodology/approach
– This paper provides the results of a recently held foresight exercise on the future development of Russia’s GLONASS system.

Findings
– The foresight exercise suggested a number niche markets where the GLONASS technology could be of great use, like monitoring of buildings and construction sides or the monitoring of shipments. In addition, in the case of Russia, large-scale government-driven investment programs will be key drivers for GLONASS’ growth perspectives.

Originality/value
– The paper provides a comprehensive picture of the development of GNSS for civilian use until 2020.
Neo-Confucianism and industrial relations in Meiji Japan
Authors: Lottanti von Mandach Stefania 
Published: October 2014

Purpose– This paper sets out to explain the poor nature of industrial relations in Meiji Japan (1868-1911), especially the puzzling lack of Neo-Confucianist values.Design/methodology/approach– This paper combines two approaches. First, it draws on and scrutinizes the major literature. Second, it uses a case approach.Findings– First, we find that a widely accepted assumption used in many management (and other) studies on Japan, namely, that Neo-Confucianism was institutionalized in Tokugawa Japan (1603-1867), is distorted. Second, we find that the poor nature of labor relations in Meiji Japan can be explained by and is the product of a multitude of factors, both indigenous and imported from abroad.Originality/value– First, this paper provides a novel explanation for the poor nature of labor relations in Meiji Japan. Second, this paper corrects a widely held assumption on Japan that is frequently used in management studies.
Effectiveness of TPM implementation with and without integration with TQM in Indian manufacturing industries
Authors: Singh Kanwarpreet , Singh Ahuja Inderpreet 
Published: October 2014

Purpose
– The purpose of this paper is to evaluate and extract various significant factors influencing the implementation of total quality management (TQM) and total productive maintenance (TPM) on business performance for the following approaches: TPM alone; both TQM-TPM combined for improving manufacturing performance in the Indian manufacturing industry.

Design/methodology/approach
– In the present study, 94 manufacturing organizations have been extensively surveyed, to ascertain the contributions made by TQM and TPM initiatives in the Indian manufacturing industries toward realizing manufacturing performance improvements. The correlations between various TQM and TPM implementation issues and manufacturing performance improvements have been evaluated and validated by employing various statistical tools.

Findings
– This paper illustrates how the synergistic relationship of TQM and TPM paradigms can be helpful for Indian manufacturing industries to enhance overall business performance. The major objectives of this research is to examine, the effectiveness of performance parameters (dependent variables) and factors of implementation (independent variables) of companies implementing TPM alone and TQM-TPM combined approach to improve their business performance and how the support of TQM provides a synergetic effect on TPM's contribution in improving better business performance.

Originality/value
– TQM and TPM, are such popular initiatives employed by the manufacturing organizations as performance improvement techniques. These programs are employed world over for attaining customer satisfaction, reliability, productivity, market share, profitability and even survival. The study stresses upon the need for improving coordination between manufacturing parameters and other organizational quality improvement initiatives through transfusion of TQM and TPM and to examine the impact of experience in terms of time period on effectiveness of performance parameters when TQM is supported by TPM for Indian manufacturing companies.
A blueprint paradox
Authors: Rolfsen Monica 
Published: October 2014

Purpose– The purpose of this paper is to investigate if a manufacturing concept such as total productive maintenance (TPM) can be copied from one location to another.Design/methodology/approach– Qualitative data were gathered from a single case. This includes interviews, participatory observation and document collection.Findings– The authors present a company with an intention to make a pure copy from one location to another, and with identical technology, production equipment, owners, customers and products, the conditions for copying should thus be as sufficient as possible. However, several minor adjustments led to a translated version showing better results than the original.Research limitations/implications– The paper provides a deep understanding of a unique case, but should be supplemented with more data in order to reach general conclusions. The main theoretical contribution is to develop an understanding of translation processes different from copying concepts by expanding models of change and transfer from a purely planned perspective to explaining success through the unplanned change of organizational vehicles better fit to the intended tools and techniques.Practical implications– Many companies struggle with implementing total productive maintenance, and implementation and translation aspects are lacking in the literature. The paper provides an understanding on how TPM-practice was changed and adjusted when travelling from one location to another within the same company.Originality/value– Few case studies on TPM and implementation have been described. The authors show in detail how minor adjustments led to wider changes, arguing that a pure copy is not possible. By including institutional theory focusing on translation, new insight on implementation of TPM is provided.
Everyday innovation – pushing boundaries while maintaining stability
Authors: Lippke Lena , Wegener Charlotte 
Published: October 2014

Purpose– The purpose of this paper is to explore how vocational teachers’ everyday practices can constitute innovative learning spaces that help students to experience engagement and commitment towards education and thus increase their possibilities for completing their studies despite notable difficulties.Design/methodology/approach– Based on two ethnographic field studies, we analyse vocational teaching situations in which teachers and students engage in daily remaking of the vocational educational training practice. It is argued that these everyday situations can be understood as innovative transformation of participation and practice.Findings– The exploration of teachers’ practicing new learning spaces sheds light on innovation potential embedded in everyday educational practices. The paper thus challenges the celebration of radical innovation and argues that innovation emerges from everyday activities in which teachers succeed to balance continuities and discontinuities. Studying innovation as a balance between change and stability thus involves emerging, negotiated processes of learning and participation in everyday practices where people talk, interact and conduct their work and studies.Practical implications– Based on the analysis, we argue that students’ engagement in education can be enhanced by transforming the educational settings on various parameters such as buildings, artefacts, emotions and experiences. Thus, innovation should be recognised as emerging everyday activities in which frontline workers like vocational teachers are drivers for innovation.Originality/value– Innovative everyday activities are often invisible; however, we suggest that they can be studied and thus become visible by use of the analytic term: “boundary-pushing“.
Towards ex-centric theorizing of work and learning
Authors: Cooper Linda 
Published: October 2014

Purpose
– This paper aims to highlight the value of research contributions that have focused on making visible the knowledge of those historically excluded from formal knowledge-making. It identifies key bodies of theory that have grounded these analyses, and questions whether we can fully do justice to this project if we continue to rely on established “canons” of social science theory.

Design/methodology/approach
– The article reviews research contributions to Researching Work and Learning conferences over the past decade, aimed at identifying those who have been invisible as makers of knowledge. It then considers a body of critique that our dominant epistemologies within the social sciences are rooted in unequal global and local power relations.

Findings
– In the literature on workplace learning, a few theoretical paradigms forged in the global north seem to predominate. The article concludes that we need to re-centre our sources of knowledge-making to what Homi Bhabha has called an “ex-centric” site, if we are to develop more inclusive theorizations of work and learning, and more socially just ways of working and learning in the future.

Originality/value
– The article invites researchers to reflect critically on their use of theory, and to be more proactive in developing theories with an angle of vision outside of the geo-political centre, so as to better understand the diversity of work and learning globally.
Learning domestic violence interagency work: enacting “practice multiple”
Authors: Stewart Sarah 
Published: October 2014

Purpose– This paper aims to shed light on the complex multiplicity of domestic violence interagency work. It proposes a new conceptualisation that reflects the entangled nature of professional practice and learning.Design/methodology/approach– The research on which this paper draws is an ethnographic study of practice in an integrated local domestic violence initiative. Data include focussed workplace observations, semi-structured interviews and key documents. The study draws on practice-based sociomaterial approaches and the conceptual framework, and methodology is informed by actor-network theory, in particular, the work of Annemarie Mol.Findings– Findings suggest that interagency work that starts from the victim and traces threads of connection outwards is able to “hang together” as “practice multiple” in integrated service provision. I argue that the learning that happens in these circumstances is a relational effect and depends on who and what is assembled in the actor-network.Research limitations/implications– The research has significant implications for framing understandings of domestic violence interagency work, as it firmly anchors “working together” to victims. Findings are expected to be of interest not only to practitioners, educators and researchers but also to policymakers.Originality/value– The paper addresses a current gap in the literature, applies a novel research approach and proposes a new conceptualisation of domestic violence interagency work.
Seeing coal‐seam top ahead of the drill bit through seismic‐while‐drilling
Authors: Zhou Binzhong , Mason Iain , Greenhalgh Stewart , Subramaniyan Shankar 
Published: October 2014

ABSTRACTBlast damage to the tops of coal seams due to incorrect blast standoff distances is a serious issue, costing the industry in Australia about one open‐cut mine for every ten operating mines. The current approach for mapping coal‐seam tops is through drilling and pierce‐point logging. To provide appropriate depth control with accuracy of ±0.2 m for blast hole drilling, it is typically necessary to drill deep reconnaissance boreholes on a 50 m x 50 m grid well in advance of overburden removal. Pierce‐point mapping is expensive and can be inaccurate, particularly when the seam is disturbed by rolls, faults, and other obstacles.Numerical modelling and prototype‐field testing are used in this paper to demonstrate the feasibility of two seismic‐while‐drilling‐based approaches for predicting the approach to the top of coal during blast hole drilling: (i) reverse “walk‐away” vertical seismic profiling recording, in which the drill bit vibration provides the source signal and the geophones are planted on the surface near the drill rig, and (ii) in‐seam seismic recording, in which channel waves, driven by the coupling to the coal of the seismic signal emitted by the approaching drill bit, are guided by the seam to geophones located within the seam in nearby or remote boreholes.
Spatial constrained inverse rock physics modelling
Authors: Moyano Bernardo , Jensen Erling H. , Johansen Tor Arne 
Published: October 2014

ABSTRACTPredicting reservoir parameters, such as porosity, lithology, and saturations, from geophysical parameters is a problem with non‐unique solutions. The variance in solutions can be extensive, especially for saturation and lithology. However, the reservoir parameters will typically vary smoothly within certain zones—in vertical and horizontal directions. In this work, we integrate spatial correlations in the predicted parameters to constrain the range of predicted solutions from a particular type of inverse rock physics modelling method. Our analysis is based on well‐log data from the Glitne field, where vertical correlations with depth are expected. It was found that the reservoir parameters with the shortest depth correlation (lithology and saturation) provided the strongest constraint to the set of solutions. In addition, due to the interdependence between the reservoir parameters, constraining the predictions by the spatial correlation of one parameter also reduced the number of predictions of the other two parameters. Moreover, the use of additional constraints such as measured log data at specific depth locations can further narrow the range of solutions.