bluuebunny/crossref_metadata_2025_split huggingface dataset:
Recurrence of Hepatocellular Carcinoma after Living Donor Liver Transplantation Prevalence, Patterns, Perioperative Factors and Outcome
Authors: El Malatawy Mohammed Abd El Fattah , Bahaa El Din Mohamed Mohamed , Mohamed Eslam Safwat , Faheem Heba Ahmed , Shawkey Isac Shadi Emad 
Published: July 2024

Abstract

Background
Hepatocellular carcinoma (HCC) is the sixth most common cancer and the third cause of cancer-related mortality world- wide. The incidence of HCC is on the increase, and it is a major threat to our modern life. Epidemiological studies have indicated that HCC are related to chronic hepatitis B virus (HBV) and chronic hepatitis C virus (HCV) infection.

Aim of the Work
To detect prevalence, patterns, perioperative factors and outcome of recurrence of HCC after living donor liver transplantation.

Patients and Methods
This was a cross sectional study based on the review of medical records of all patients undergoing LT at Ain Shams Centre of Transplantation, between January 1, 2010, and December 31, 2018.

Results
we detected prevalence, patterns, perioperative factors and outcome of recurrence of HCC after living donor liver transplantation.

Conclusion
Oral lactoferrin could not be used as a substitute to totally replace IV ferrous sulphate in treating iron deficiency anemia in end stage renal disease (ESRD) on dialysis. Oral lactoferrin could not even control Hb level constant without dropping in patients with end stage renal disease (ESRD). Oral lactoferrin had some gastrointestinal effects on some patients which did not allow compliance on the medication.
The Diagnostic Value of Monocyte Count/HDL Cholesterol Ratio as a New Marker in Diabetic Retinopathy
Authors: Abd El Baky Rania Sayed , Bekhet Meram Mohamed , Aly Salah Hussein , El Gayed Ahmed Amany Talaat Abd 
Published: July 2024

Abstract

Background
Diabetes mellitus is a set of metabolic diseases characterized by chronic hyperglycemia as a consequence of lack in insulin action, secretion, or both. All of which lead to long-term damage and dysfunction of different organs predominantly the eyes, kidneys, nerves, heart, and blood vessels.

Aim of the Work
The aim of the study is to investigate the diagnostic value of MHR in diabetes and whether it can be utilized as an indicator of diabetic retinopathy.

Patients and Methods
This study was a case control study on 100 patients attending diabetes outpatient clinic at Ain shams university hospital 30 male, 70 female. 50 patient with diabetic retinopathy and 50 patient without retinopathy to detect the MHR in each group and to detect whether it can be utilized as an indicator of diabetic retinopathy.

Results
In this study there is a significant correlation between diabetic retinopathy and MHR, MHR being higher in patient with diabetic retinopathy, with a cut-off level of &gt; 0.01 with 74% sensitivity and 64% specificity. Our study showed a significant relation between long standing duration of diabetes mellitus and diabetic retinopathy. Also there was significant relation between diabetic retinopathy with high glycemic profile with fasting blood sugar and 2 hour post prandial blood sugar and Hba1c. The study also show that there is no significant relation between diabetic retinopathy and weight, height, BMI.

Conclusion
Diabetic retinopathy (DR) is a major complication of diabetes mellitus (DM), which remains a leading cause of visual loss in working-age populations. MHR being higher in patient with diabetic retinopathy. And can be it can be utilized as an indicator of diabetic retinopathy.
Serum Selenium Status in Egyptians Patients who had Graves’ Disease with and without Ophthalmopathy
Authors: Hasanin Ghada Atef , Mohamed Magda Shokry , Maher Maram Mohamed , Ali Hanan Mahmoud , Mansour Hany Khairy , Ahmed Said Azza Mohamed 
Published: July 2024

Abstract

Objective
Selenium is effective in improving quality of life and reducing the progression of active Graves’ orbitopathy. The effect of correcting relative selenium deficiency on improving Graves’ orbitopathy is unknown, as baseline selenium levels have not previously been measured. The study aims to determine whether serum selenium levels are reduced in patients with Graves’ disease with orbitopathy (GO) compared with without orbitopathy (GD).

Design
A prospective, case–control study performed between 2019 and 2021 at endocrine and ophthalmology clinics in Ain SHams University, Cairo.

Subjects
A total of 75 subjects, 25 as control and a total of 50 patients with Graves’ disease participated in the study: 25 with Graves’ orbitopathy and 25 without Graves’ orbitopathy. Measurements Serum selenium levels in all groups.

Results
Mean serum selenium levels were significantly lower in GO (16.6 +- 7.5 ng/ml) than in GD (42.9 +- 8.2 ng/ml) with (P &lt; 0.001). Mean selenium levels appeared to decrease in parallel with increasing severity of GO; selenium level was 30-55 ng/ml in GD, 21-28ng/ml in mild GO, 18-22 ng/ml in moderate GO and 5-16 ng/ml in severe GO (P &lt; 0.001).

Conclusion
Serum selenium levels are lower in patients with GO compared with GD in an Egyptian study population with marginal selenium status. selenium deficiency may be an risk factor for orbitopathy in patients with Graves’ disease.
Association of Serum M2BPGi Levels with Nutritional Status (Using CONUT score) in Hepatitis C Virus Related Compensated Liver Cirrhosis Patients
Authors: Keddeas Marcel William , Kaisar Hany Haroun , Elessawy Hagar Ahmed , Abosree Mohamden Nahla Mohsen 
Published: July 2024

Abstract

Background
Protein-energy malnutrition (PEM), which is one of the most common complications seen in LC patients and associated with high morbidity and mortality. So, predicting the presence of PEM and providing appropriate nutritional support help improve the prognosis of those patients. Mac-2-binding protein glycosylation isomer (M2BPGi) was recently identified as a serum glycobiomarker for liver fibrosis. However, the relationship between M2BPGi and malnutrition in patients with chronic liver disease (CLD) is unclear.

Aim of the Work
The aim of this study is to evaluate the role of serum M2BPGi levels as a surrogate marker for malnutrition in HCV related cirrhotic patients, correlated with CONUT score as the nutritional status marker.

Patients and Methods
This is a Cross-sectional - Analytic study that included patients with chronic HCV infection and normal control group selected from patients attending to Hepatology Outpatient Clinics at Ain Shams University Hospital. This study was carried out from 30 patients (child A) attending to Hepatology Outpatient Clinics at Ain Shams University Hospital and 30 healthy individuals as a control.

Results
The M2BPGi levels increased with CONUT score. The correlation coefficient between M2BPGi and CONUT score was r = 0.315 (p = 0.05), indicating a positive weak correlation between M2BPGi and CONUT score. The cut-off for M2BPGi to predict CONUT low vs. moderate was 1.43 with a sensitivity 93.33% and specificity 100% when AUC =0.9 and CONUT moderate vs. severe was 1.7 with a sensitivity 91.67% and specificity 100% when AUC =0.9.

Conclusion
We found that there is correlation between M2BPGi and CONUT score and both can be useful as a marker for malnutrition in HCV related cirrhotic patients cut of point
Impact of Nutrition Education on the Outcome of Bariatric Surgery
Authors: Hamed Elagroudi Reham Mohammed , Ibrahim Wesam Ahmed , Zaky Doaa Zakaria , Anwar Christina Alphonse , Abdelaziz Mohamed Magdy 
Published: July 2024

Abstract

Background
Bariatric Surgery is the most effective way for inducing long term weight loss and decreasing comorbidities and mortality in patients with severe obesity. After the surgery, nutritional counselling is important to facilitate the adaption of eating habit to the new gastric intestinal physiology and to prevent the nutritional deficits arising after the bariatric surgery.

Aim of the Work
Assess impact of nutrition education no outcome of bariatric surgery regarding dietary habits and clinical parameters.

Patients and Methods
This study was carried out on 128 bariatric patients, 64 patients underwent bariatric surgery and took nutritional education session and follow-up for 6months from the first day of performing the operation (Group A), and another 64 bariatric patients performed the surgery six month ago without taking the nutritional education session or any follow-up (Group B).

Results
In Group A (with the nutritional education intervention) there was a statistically significant difference in the eating after bariatric surgery knowledge, taking supplementation, satisfaction level after the surgery, eating habits, anthropometry and weight loss measurements, improving nausea and vomiting symptoms, and better Hb%, albumin level, and improvement in serum TG level, Serum LDL level which decreased and also improvement of HDL level which increased at the six month of performing the operation more than Group B (without the nutritional education intervention).

Conclusion
There is a great importance of nutritional education and compliance to the follow-up after performing the bariatric surgery on the outcome of the bariatric surgery regarding dietary habits and clinical parameters.
Effect of Parathyroid Hormone on Left Ventricular Hypertrophy in Patients on Regular Hemodialysis
Authors: Botros Raef Malak , Bekhet Meram Mohamed , Mohamed Amr Mahmoud , Helmy Marina Nashaat 
Published: July 2024

Abstract

Background
Cardiovascular disease is the most common cause of death in patients with end-stage renal disease (ESRD) and accounts for much of the morbidity in this population.

Aim of the Work
We therefore aimed to consider the evidences regarding the role of excess PTH in the development of left ventricular (LV) hypertrophy as well as LV ejection fraction in patients with end-stage renal disease under regular hemodialysis.

Patients and Methods
This study was cross sectional study and was conducted in hemodialysis unit, Elsahel Hospital. This study was conducted on 70 patients on regular hemodialysis (3 times a week for at least 6 months) for timing of study from January 2022 to June 2022.

Results
In our study, we demonstrated that there was statistically significant relation between P.T.H quartiles and LVMI which found higher in 2nd quartile and lower in 3rd quartile with p-value = 0.036. Our results showed that there was statistically significant positive correlation found between LVMASS and AP, LVEDD, PWT, IVST and LVMI and also negative correlation between LVMASS and weight, BMI and EF% among female patients.

Conclusion
our study suggested the role of hyperparathyroidism in the development of LVH, with a potential impact on cardiovascular outcome for patients on HD. Adverse effects of secondary hyperparathyroidism on LV function and structure showed the role of excess PTH in the development of left ventricular (LV) hypertrophy as well as low LV ejection fraction in patients with end-stage renal disease under hemodialysis which needs more attention to control of secondary hyperparathyroidism to reduce the risk of cardiovascular morbidity and mortality in dialysis patients.
Relationship between Serum Zinc Level and Retinopathy in Type 2 Diabetic Patients
Authors: Eid Yara Mohamed , Ibrahim Wesam Ahmed , Abdelbaky Rania Sayed , Aly Elhalawany Salah Hussein , El Sayed Nouh Mona Ahmed 
Published: July 2024

Abstract

Background
Diabetes mellitus (DM) is a metabolic disorder characterized by chronic hyperglycemia caused by insulin resistance (IR) or impaired insulin production. Diabetic retinopathy (DR) is a common microvascular disorder which occurs in type 2 diabetes mellitus (T2DM) patients due to chronic hyperglycemia. Previous studies reported that serum zinc (Zn) was associated with certain diabetic microvascular complications.

Objective
To evaluate relation between serum zinc level and diabetic retinopathy in patients with type 2 diabetes mellitus.

Subjects and Methods
The current study included 60 subjects with their ages ranging from 18- 60, selected from diabetes and ophthalmology outpatient clinics of Ain Shams University Hospitals for 7 months in a period from July 2022 to January 2023 with matched age and sex . fasting and post prandial blood glucose, hemoglobin A1c (HbA1c), systolic blood pressure (SBP), diastolic blood pressure (DBP),serum creatnine, LDL, HDL, TG,TC and serum zinc levels were measured among groups.

Results
The study shows statistically significant difference between DM type II subgroups regarding duration of disease (yrs) being higher in DM II with retinopathy 12.5 (10.5 – 16.5) than DM II without retinopathy 9 (6 – 12) with p &lt; 0.001. serum Zn levels were significantly lower in the DR group than the controls and diabetic without retinopathy.in whole DM type II group, there was statistically significant negative correlation found between zinc level and duration of diabetes, HbA1c, LDL, TC, FBS, 2PP and serum creatinine level, while in DM II without retinopathy there was statistically significant negative correlation found between zinc level and duration of diabetes, LDL, TC and FBS and also in DM type II retinopathy there was statistically significant negative correlation found between zinc level and duration of diabetes, HbA1c, FBS, 2PP and serum cretainine level .There is no statistically significant difference found between control group and DM type II group regarding weight, height and BMI of the studied patients with p-value = 0.108, 0.198 and 0.343; respectively. There is no statistically significant difference found between control group and DM type II group regarding systolic and diastolic blood pressure of the studied patients with p- value = 0.554 and 0.405; respectively.

Conclusion
Our study suggested that lower serum zinc level in T2D patients was related to higher prevalence of diabetic microvascular complications. Patients with lower serum zinc level were more likely to have a longer duration of diabetes, poorer glucose control, and worse β-cell function. Older age, higher HbA1c level, and the prevalence of DN were risk factors related to the lower serum zinc level.
Selfie Phenomenon among a Sample of Egyptian University Students: Rate and Psychiatric Correlates
Authors: Mohamed Hashem Reem El Sayed , Hassan Ghada A M , EL-sheikh Mona Mahmoud , Hassan Hadeer , Ismail Azzam Lobna Abu-Bakr 
Published: July 2024

Abstract

Background
The SELFIE phenomenon being an emanating one, specifically affecting adolescents and young adults. It emerges as a reflection of a wide spectrum of Neuro- psychiatric disorders. Based on this, the current study aimed to assess the rate of the selfie phenomenon among Egyptian university students, and its sociodemographic and psychiatric correlates. During the study procedure we enrolled 200 undergraduate Egyptian university students from two different faculties and were assessed using the Selfie Behavioral Scale, Structured Clinical Interview for DSM-IV- TR Axis I Disorders, Structured Clinical Interview for DSM-IV- TR Axis II Disorders, and Global assessment of functioning scale.

Results
49.5 % of the students being assessed had borderline selfitis with a higher rate among females, we found a highly significant relationship between the selfie phenomenon and depression, anxiety, obsessive-compulsive disorder, eating disorders, and other psychiatric disorders and personality disorders, we also found that selfie had a significant negative correlation with the level of functioning among students.

Conclusions
results concur with previous existing literature regarding the magnitude of the selfie phenomenon and its relationship with .different psychiatric disorders and personality disorders.
Sleep Disorders Linked to Quality of Life in a Sample of Egyptian Policemen a Comparative Study between Shift Workers and Non-Shift Workers
Authors: Omar Abdelnasser Mahmoud , Elkhayat Naglaa Mohamed , Khalil Sherien Ahmed , Naguib Rehab Mohamed , Mohamed Kotb Mostafa Ahmed 
Published: July 2024

Abstract

Background
Poor sleep is associated with bad health outcomes, worse wellbeing and decreases in performance, productivity and safety at work. Police officers are exposed to several risk factors including extended work schedules, shift work, occupational stress, dangerous and traumatic events and can, as such, develop sleep problems.

Aim and Objectives
To compare quality of life, occupational stress level, between shift &non shift workers policemen working at El-Agouza Police Hospital.

Subjects and Methods
This was a cross-sectional comparative study conducted on 64 policemen working in 6 different Police department recruited from sleep clinic neuropsychiatry department at EL-Agouza Police Hospital serving police officers in El-Nile street, Giza, Egypt.

Result
Occurrence of sleep disorders was significantly higher in the shift workers compared to the non-shift worker group (p &lt; 0.01).

Conclusion
In the current population-based study of police officers, poor sleep quality was more prevalent among officers who were engaged in shift work. The findings are consistent with prior evidence that night shift carried the greatest risk of poor sleep quality because night-shift officers have to make some adaptations that compensate for their natural circadian patterns.
A Systematic Review Comparing Fusion Rates and Cage Subsidence in ACDF by Cage Alone vs Cage and Plate in Multilevel Cervical Disc Prolapse
Authors: Abdel Hamid Ahmed Wael Hamed , Khalil Hamdy Ibrahim , Elsayed Ahmed Mohammed , Elmashad Mohammed Gamal 
Published: July 2024

Abstract

Background
Anterior cervical discectomy and interbody fusion (ACDF) has become the standard procedure for treating degenerative cervical disc disease. Multiple techniques and modalities of fixation are used in ACDF, each with its merits and demerits.

Aim of the Work
The objective of this study is to compare the outcome of anterior cervical discectomy and fusion by cage alone versus surgical fusion by cage and plate in terms of morbidity, mortality, fusion rates, cage subsidence and quality of life estimates in treatment of multilevel cervical disc prolapse.

Patients and Methods
Our search strategy identified a total of 235 citations. Search was done for studies conducted or published within 2010 – 2022. After removal of 58 duplicate studies, eligibility criteria was applied to the titles of 177 articles with the exclusion of non-appropriate study design. This yielded 21 studies that underwent full text analysis of which 13 did not meet the inclusion criteria for having only single level ACDF or short follow up period.

Results
Our study included 8 observational studies (6 retroscpective and 2 prospective) comparing multilevel ACDF with cage alone vs cage and plate regarding fusion rate and cage subsidence, the results showed that while the cage plate group had lower rate of cage subsidence, there was no significant difference in the rate of fusion.

Conclusion
Our study included 8 observational studies (6 retroscpective and 2 prospective) comparing multilevel ACDF with cage alone vs cage and plate regarding fusion rate and cage subsidence, the results showed that while the cage plate group had lower rate of cage subsidence, there was no significant difference in the rate of fusion.
Effect of Primary Arthroplasty on Post Treatment Results among Elderly with Pertrochanteric Femur Fracture
Authors: Awad Mahmoud Mostafa , Basiouny Ayman Abdelaziz , Sayed Kotb Ahmed 
Published: July 2024

Abstract

Background
With an increasing global incidence of hip fractures, designing ppropriate treatment strategies for hip fractures is fundamentally important to healthcare professionals. Evaluation of the role of 1ry arthroplasty in the setting of trauma for the acute treatment of hip fractures will be fulfilled.

Aim of the Work
to review the literature to know the best arthroplastic option for elderly people with pertrochantric fracture and compare between them as regard post-operative complications (infections, bed sores, pneumonia and other chest infections, dislocations), post-operative functional outcome, post-operative dislocation, rate of revision surgrey.

Patients and Methods
The included studies were randomized controlled trials, including cluster RCTs, controlled (non-randomized) clinical trials or cluster trials, prospective and retrospective comparative cohort studies, and case-control or nested case-control studies. The excluded studies were cross-sectional studies, case series, case reports and literature not in English.

Results
after extraction of non-compatible studies as regard our priciples, we setteled on 18 studies that compare different types of primary arthroplasty and their post operative outcome among elderly with pertrochanteric femur fracture. We found some heterogenty in the results of some studies but we overcome this problem by using other methods for comparison.Another problem is lack of studies that compare among interventios in some comparative points. Among these studies We found that, as regard postoperative functional outcome and harris hip scoring (HHS), dual mobility arthroplasty(DMA) is higher than Total Hip Arthroplasty (THA). Total hip arthroplasty (THA) is also higher than (BHA) in the score.

Conclusion
As the general population is getting older while staying active, faster and more complete rehabilitation as well as decreased complication rate must be achieved for these patients.
Anterior Cruciate Ligament Reconstruction using Peroneus Longus Tendon Autograft (Systematic Review and Meta-Analysis)
Authors: Khater Ahmad Hany , Hemida Mohamed Amr , Elsayed Ghonim Samir Sabry 
Published: July 2024

Abstract

Background
The ACL is the most commonly injured ligament in the knee, controversy exists about the most suitable graft for ACLR.

Aim of the Work
This study aims to assess the efficiency of PLT autograft as a good alternative graft choice for ACLR and to outline the advantages and disadvantages of its use.

Methodology
We searched the literature through PUBMED, Cochrane library, Medscape, direct science, JBJS and Google scholar with publication date restricted to 10 years range from 2012-2022. English literature of prospective studies only were selected with strict inclusion criteria where human studies undergoing Arthroscopic ACLR using PLT autograft which commenting on clinical +/- imaging outcomes and repeated studies excluded. Eleven studies were included satisfying the predetermined inclusion criteria with total of 564 patients. Four literatures compared ACLR using peroneus longus tendon autograft versus Hamstring tendon,1 literature versus Semitendinosus graft and another versus Patellar tendon. After pooling of collected data from the desired search studies, the relative risk of each of intended outcome measures of interest was calculated and tabulated according to IKDC and AOFAS score.

Results
In 4 literatures, in total, outcomes of 108 PLT versus 129 HT autografts were analyzed with mean follow up 10.5 months, reported little difference was found between the two grafts in favor of PLT autograft, with mean score 95.58 for PLT versus 91.65 for HT. Outcomes of 15 PLT versus 15 semitendinosus autografts were analyzed. PLT autograft gave better clinical and biomechanical outcomes than semitendinosus graft as mean IKDC score was 91.58 for PLT versus 88.37 for semitendinosus graft. Outcomes of 50 PLT versus 50 Patellar tendon autografts were analyzed and reported that PLT autograft has better IKDC score than patellar tendon autograft (96.8 versus 95.1) and lower graft rupture rate (6% versus 10%). In 5 literatures, in total, outcomes of 189 patients, had ACLR using PLT autograft, were analyzed after mean follow up 12.4 months and revealed that mean IKDC score was increased from 64.7 preoperative to 97.8 postoperative. PLT harvest does not appear to affect foot and ankle function to any clinically significant degree with slightly decreased AOFAS score (96.88 ± 4.95).

Conclusion
PLT autograft consider a very promising and ideal graft option for ACLR with excellent functional and biomechanical outcomes. PLT harvest is easy and causes minimal donor-site morbidity.