bluuebunny/crossref_metadata_2025_split huggingface dataset:
The impact of strawflower and mistletoe extract on quality properties of rainbow trout fillets
Authors: Özogul Fatih , Kus Bünyamin , Kuley Esmeray 
Published: June 2013

SummaryMany plants, including strawflower and mistletoe, contain antioxidants and antimicrobials, which can increase the shelf life of seafood. The main aim of this study was to investigate the effect of mistletoe and strawflower extracts at doses of 0.5% (w/v) on the sensory, chemical and microbiological properties of rainbow trout fillets during 27 days of storage at 2 ± 1 °C. The phenolic compounds in these plants have been studied, but their effects on food quality and storage properties have not been reported. We found that extract of mistletoe did not extend the shelf life of the fillets; however, the strawflower extract show high antimicrobial activity in fish fillets. The shelf life of rainbow trout was 20 days for the control and fish treated with mistletoe extract and 23 days for fish treated with strawflower extract. The antioxidant effect of extracts on fish fillets was weak, whereas strawflower extract had high antimicrobial effect. Peroxide value (PV) and thiobarbituric acid (TBA) values fluctuated during storage periods around main values below 14 meq O2 kg−1 and 0.6 MA kg−1, respectively. Putrescine, cadaverine, spermine, spermidine, serotonin, tyramine and dopamine were main amine, whereas histamine accumulated at low levels (<2 mg per 100 g). Strawflower suppressed biogenic amine accumulation in fish fillets. At the limit of acceptability, total viable count (TVC), Enterobacteriaceae and lactic acid bacteria count remained below 7.6, 6.83 and 8.01 log CFU g−1, respectively. The results of this study show that ethanol extracts of strawflower improve the shelf life of rainbow trout.
Self‐reported quantity of normal maximal voided volume in healthy young
Authors: Altun İnsaf , Cınar Nursan Dede 
Published: June 2013

ABSTRACTBladder capacity is an important factor in the diagnosis and treatment of individuals with voiding dysfunction. In contrast, self‐reported quantity of normal maximal voided volume in healthy young is few.The purpose of this study was to define the quantity of normal maximal voided volume in healthy young. This prospective study was carried out in 72 students aged 17–24 years who did not have clinical voiding dysfunction undergoing nursing education in a University in Sakarya, Turkey. The study was conducted in December 2011. Healthy young were recruited to determine the quantity of the normal maximal voided volume. The maximal voided volume was determined in all subjects using a frequency volume chart with a voiding observation.In our study, the normal maximal voided volume (mL) for females was 413·3 ± 167.9 and the normal maximal voided volume (mL) for male was 589·2 ± 108·5.These formulas may be useful for the diagnosis of abnormal bladder capacity and the evaluation of voiding dysfunction in young. This research may be the source for studies that could include climate, cultures and different age groups.
Effects of HCV Seropositive Status on Buprenorphine Pharmacokinetics in Opioid‐Dependent Individuals
Authors: Masson Carmen L. , Rainey Petrie M. , Moody David E. , McCance‐Katz Elinore F. 
Published: June 2013

Background and ObjectivesThe purpose of this study was to examine the effect of hepatitis C virus (HCV) infection on buprenorphine pharmacokinetics in opioid‐dependent, buprenorphine/naloxone‐maintained adults.MethodsA retrospective analysis of buprenorphine pharmacokinetics in HCV seropositive and seronegative buprenorphine/naloxone‐maintained individuals (N = 49) was undertaken.ResultsRelative to HCV seronegative subjects, HCV seropositive subjects had higher buprenorphine exposure, as demonstrated by elevated buprenorphine AUC and Cmax values (p = .03 and .02, respectively) and corresponding elevations in the metabolites, buprenorphine‐3‐glucuronide AUC values (p = .03) and norbuprenorphine‐3‐glucuronide AUC and C24 values (p = .05 and .03, respectively).Discussion and ConclusionsHCV infection was associated with higher plasma concentrations of buprenorphine and buprenorphine metabolites.Scientific Significance and Future DirectionsFindings suggest the potential for opioid toxicity among HCV‐infected patients treated with buprenorphine/naloxone, and possible hepatotoxic effects related to increased buprenorphine exposure. HCV‐infected patients receiving buprenorphine may need lower doses to maintain therapeutic plasma concentrations. (Am J Addict 2014;23:34–40)
The Waterpipe: A New Way of Hooking Youth on Tobacco
Authors: Maziak Wasim 
Published: June 2013

BackgroundTobacco smoking continues to be the number one preventable cause of morbidity and mortality worldwide. Several evidence‐based interventions and policies have been successful in reducing cigarette smoking in developed countries. Globally, however, many beginning smokers are introduced to tobacco by means other than cigarettes. In particular, waterpipe smoking (a.k.a. hookah, narghile, shisha) has been dramatically increasing among youth worldwide.MethodsIn this short review, I will introduce the reader to this emerging tobacco use method and focus on its addictive properties, and how this pertains to the development of effective interventions to curb its spread.Results and ConclusionsWaterpipe smoking is likely to be associated with much of the harmful effects of cigarette smoking, is addictive, and can serve as a bridge to cigarettes. Due to its unique features, waterpipe‐specific interventions and policies are needed to curb the global waterpipe epidemic. (Am J Addict 2014;23:103–107)
Search strategies in systematic reviews in periodontology and implant dentistry
Authors: Faggion Clovis M. , Atieh Momen A. , Park Stephanie 
Published: June 2013

AbstractObjectiveTo perform an overview of literature search strategies in systematic reviews (SRs) published in periodontology and implant dentistry.Materials and MethodsTwo electronic databases (PubMed and Cochrane Database of SRs) were searched, independently and in duplicate, for SRs with meta‐analyses on interventions, with the last search performed on 11 November 2012. Manual searches of the reference lists of included SRs and 10 specialty dental journals were conducted. Methodological issues of the search strategies of included SRs were assessed with Cochrane collaboration guidelines and AMSTAR recommendations. The search strategies employed in Cochrane and paper‐based SRs were compared.ResultsA total of 146 SRs with meta‐analyses were included, including 19 Cochrane and 127 paper‐based SRs. Some issues, such as “the use of keywords,” were reported in most of the SRs (86%). Other issues, such as “search of grey literature” and “language restriction,” were not fully reported (34% and 50% respectively). The quality of search strategy reporting in Cochrane SRs was better than that of paper‐based SRs for seven of the eight criteria assessed.ConclusionThere is room for improving the quality of reporting of search strategies in SRs in periodontology and implant dentistry, particularly in SRs published in paper‐based journals.
Carotid ultrasonography: A potent tool for better clinical practice in diagnosis of atherosclerosis in diabetic patients
Authors: Katakami Naoto , Kaneto Hideaki , Shimomura Iichiro 
Published: June 2013

AbstractCardiovascular disease (CVD) remains the main cause of death in diabetic patients, and once it has developed, diabetic patients have a worse outcome as compared with non‐diabetic patients. One reason for this is the difficulty of early diagnosis of atherosclerotic change in these patients. Although cardiovascular risk assessment based on conventional risk factors is recommended for predicting cardiovascular risk, validation studies showed only moderate performance. In contrast, it is unrealistic to screen for subclinical or silent atherosclerosis by sophisticated modalities, such as myocardial perfusion scintigraphy, coronary computed tomography angiography or conventional angiography in all diabetic patients, as these tests are limited by the potential of significant adverse effects, technical difficulty, availability and high cost. Therefore, a non‐invasive and inexpensive tool for risk prediction of subclinical atherosclerosis is required for identifying individuals at high risk of CVD. Recently, a number of studies have shown close associations between carotid atherosclerosis and cerebrovascular or coronary artery disease. Carotid ultrasonography has allowed clinicians to visualize the characteristics of the carotid wall and lumen surfaces to quantify the severity of atherosclerosis. Carotid intima‐media thickness (IMT) is an especially useful marker of the progression of atherosclerosis throughout the body, and is an excellent predictor of cardiovascular events. As a simple and non‐invasive procedure, measurement of carotid IMT is one of the most appropriate screening methods to specify high‐risk individuals in subjects with and without diabetes. Therefore, it is expected that carotid ultrasonography will become a potent tool for better clinical practice of atherosclerosis in diabetic patients.
Effect of organizational factors and work environments on newly graduated nurses' intention to leave
Authors: Ishihara Itsuko , Ishibashi Yukie , Takahashi Kiyomi , Nakashima Mitsuyo 
Published: June 2013

AbstractAimThe purpose of this study was to investigate intention to leave in relation to organizational factors and work environments among newly graduated nurses (NGN).MethodsA questionnaire was delivered to NGN (n = 762) from baccalaureate programs as well as diploma schools from 19 R‐hospitals (R‐hospitals were designated as “public medical institutions” by the 1951 Medical Law) in 2010. Spearman's rank correlation coefficients and Mann–Whitney U‐test were used to test statistical significance.ResultsOnly 148 questionnaires were returned for a return rate of 19.4%. The authors found that 8.1% of respondents had a highly to extremely likely desire to leave nursing. Intention to leave was significantly associated with Nursing Work Index total (P < 0.01), social support (P < 0.001), work barriers (P < 0.001), commitment to workplace (P < 0.001), job satisfaction (P < 0.001), and burnout (P < 0.001). Those who graduated from R‐schools run by the R‐organization had significantly positive impressions of their organizations and significantly lower intentions to leave compared to other graduates.ConclusionThe study results suggest that NGN intention to leave the workplace and nursing predict actual early intention to leave. In order to reduce burnout and turnover, support from colleagues and supervisors appears to be essential in organizational and psychosocial work environments for NGN to experience job satisfaction and be committed to their workplace. The results of this study also suggest that a longitudinal study is needed to reveal the long‐term effects of organizational factors and work environments on NGN and how they impact role transition and adaptation of the NGN to professional practice roles.
A Rasch‐based dimension of delivery experience: spontaneous vs. medically assisted conception
Authors: Mannarini Stefania , Boffo Marilisa , Bertucci Veronica , Andrisani Alessandra , Ambrosini Guido 
Published: June 2013

Aims and objectivesTo devise a set of indices representative of a latent dimension of delivery perception, aimed at the assessment of birth experience after both spontaneous and medically assisted conception.BackgroundBirth experience is of great importance for its prognostic value for the woman and newborn's psychophysical well‐being, especially after the experience of assisted reproduction technology. Up to date, a delivery perception assessment measure targeted to both spontaneously and medically assisted conceiving women does not exist yet.DesignMeasure development and psychometric analysis; quantitative and qualitative analysis of women's delivery experience measures.MethodsThirty‐one indices characterising seven relevant aspects of birth perception were devised from the literature and evaluated on a 4‐point Likert‐type scale by 98 childbearing women (54 spontaneously and 44 medically assisted conceiving) in the 24–48 hours postpartum time frame. Women's obstetric history information was also collected. The dimension psychometric definition was pursued within a latent trait perspective, by applying the many‐facet Rasch measurement model.ResultsA latent delivery perception dimension composed of 18 valid and reliable indices, qualifying six labour and delivery perception clinical aspects, was identified. Medically assisted conceiving women evidenced a more positive birth perception, but when analysing each index, they showed peculiar intense worries about themselves and their baby's health, even if they felt more satisfied, safer and stronger in almost every labour and birth aspect.ConclusionsThe delivery perception dimension integrates all relevant birth experience aspects in 18 easy‐to‐administer indices and provides a valid, reliable and feasible assessment tool for both the clinical practice and research purposes.Relevance to clinical practiceThe delivery perception dimension clearly discriminates between women's types of conception and identifies relevant differences in their birth experience, which are interesting for their clinical implications within a prognostic and intervention perspective of support provision in the early postpartum period.
Genome variation and personalized cancer medicine
Authors: Hudson T. J. 
Published: June 2013

AbstractGenomic variation, through effects on gene structure and expression, plays an important role in understanding disease predisposition, biology and clinical response to therapy. Transforming this knowledge into clinically relevant information that tailors interventions to an individual's specific genetic, physical, social and environmental profile is challenging. To illustrate how research initiatives at preclinical phases of development are attempting to address clinically important issues in oncology, six clinical problems related to cancers of the colon, prostate, breast, pancreas and brain (medulloblastoma) as well as metastatic disease of different origins are described. A unifying theme across applications is that healthy individuals previously indistinguishable in regards to cancer risk and patients with cancer previously categorized as similar with regard to prognosis or drug response are being stratified into more refined subgroups with different clinical profiles. Effective matching of a broad range of tests with more tailored strategies for prevention and/or treatment will require well‐designed clinical studies to evaluate benefits and costs.
Different Stages of White Matter Changes in the Original HDLS Family Revealed by Advanced MRI Techniques
Authors: Sundal Christina , Jönsson Lars , Ljungberg Maria , Zhong Jianhui , Tian Wei , Zhu Tong , Linden Thomas , Börjesson‐Hanson Anne , Andersen Oluf , Ekholm Sven 
Published: June 2013

ABSTRACTBACKGROUNDThe temporal evolution of white matter (WM) changes on MR examinations in hereditary diffuse leukoencephalopathy with spheroids (HDLS) is largely unknown. Our purpose was to investigate the evolution of these WM changes with diffusion weighted/tensor imaging (DWI/DTI) and MR Spectroscopy (MRS).METHODSA newly diagnosed patient with HDLS from the original Swedish family was followed prospectively with 5 MRI as well as DWI/DTI and MRS examinations during 16 months.RESULTSThe DTI eigenvalues demonstrated changes that suggested early myelin and axonal disturbances in the normal appearing WM (NAWM). DWI/DTI showed a rim of decreased diffusion progressively expanding through the WM from the initial frontal periventricular zones, and indicated complete destruction of axons and myelin in the area behind the front. MRS findings were suggestive of axonal destruction in the NAWM.CONCLUSIONWe describe HDLS changes in three temporal stages of development corresponding to lesions outside, in the vicinity of, and behind a characteristic rim centrifugally progressing from the ventricular horns. The axonal disturbances indicated by MRS changes in the NAWM support a primary axonal degeneration, as proposed in the original HDLS report, rather than axonal degeneration secondary to demyelination. These findings could help in differential diagnosis of HDLS.
MR Neurography in Diagnosing Nondiabetic Lumbosacral Radiculoplexus Neuropathy
Authors: Filosto Massimiliano , Pari Elisa , Cotelli Mariasofia , Todeschini Alice , Vielmi Valentina , Rinaldi Fabrizio , Padovani Alessandro , Gasparotti Roberto 
Published: June 2013

ABSTRACTHere we describe the imaging findings in a 73‐year‐old woman who had pain in the right inguinal region, followed by progressive weakness of muscles innervated by the right femoral and obturator nerves, diagnosed as nondiabetic lumbosacral radiculoplexus neuropathy. Magnetic resonance neurography showed thickening and increase in signal intensity of the right femoral and obturator nerves.
Relationships between sleep disruptions, health and care responsibilities among mothers of school‐aged children with disabilities
Authors: Bourke‐Taylor Helen , Pallant Julie F , Law Mary , Howie Linsey 
Published: June 2013

AimSleep problems are more common among children with disabilities. Mothers are likely to provide night‐time care. Mothers of children with disabilities are known to experience high levels of stress and mental health issues compared with other mothers. Relationships between a child's sleep problems, and chronic maternal sleep interruption and subjective health have not been researched.MethodCross‐sectional mail‐out survey with follow‐up phone call was used. Instruments included the Short Form 36 version 2 and instruments that measured maternal, child and sleep characteristics. Descriptive statistics examined characteristics of participants and correlation, and Kruskal–Wallis test was used to determine important maternal and child characteristics around sleep issues.ResultsAll mothers (n = 152) cared for a school‐aged child with a developmental disability including autism spectrum disorder (n = 94) and cerebral palsy (n = 29). Nearly half (49%) of the mothers were awoken more than 4 nights/week. Three distinct sleep groups were identified: no sleep interruption; sleep interruption once/night, 4 nights/week; and more frequent interruption. Mothers experiencing the most sleep interruptions reported significantly poorer health on six Short Form 36 version 2 dimensions. Night‐time caregiving was associated with higher child care needs rather than children's diagnoses. Mothers who experienced more sleep interruption also participated less in health‐promoting activities (active leisure, time with socially supportive others) during the day.ConclusionThis study identifies a group of mothers with chronic sleep interruption and demonstrates related poor maternal subjective health and lower participation in health activities that may service to support maternal health. Mothers with children with the highest daytime care needs also experienced high night‐time care responsibilities. Changes to service provision are recommended to identify mothers in need of additional supports and services.
Neural representations of perceptual and semantic identities of individuals in the anterior ventral inferior temporal cortex of monkeys
Authors: Eifuku Satoshi 
Published: June 2013

AbstractSince the discovery of “face cells” in the early 1980s, single‐cell recording experiments in nonhuman primates have made great contributions toward elucidation of the neural mechanisms underlying face perception and recognition. In this article, I review the recent progress in face cell studies, including recent research into the face patches scattered around the anterior temporal cortical areas of monkeys. In particular, I focused on the neural representations of individual identity in these areas. Several groups have shown that the population of face cells in the anterior ventral inferior temporal cortex of monkeys represents the perceptual identity of faces in a view‐invariant manner. In this context, I also summarized our own study showing that the face‐cell population in the anterior ventral inferior temporal cortex of monkeys, which represents the perceptual identity of the faces, can also represent the semantic identity of the individuals; the learned paired associations between an abstract picture and a particular facial identity were also represented in the anterior ventral IT cortex.
Endothelin‐1 Concentrations in Bronchoalveolar Lavage Fluid of Cats with Experimentally Induced Asthma
Authors: Sharp C.R. , Lee‐Fowler T.M. , Reinero C.R. 
Published: June 2013

BackgroundThere is a need for biomarkers for diagnosis, therapeutic monitoring, and prognosis for asthma in cats. Endothelin‐1 (ET‐1) is implicated in the pathogenesis of inflammatory airway diseases in other species but not the cat.ObjectiveTo conduct a prospective experimental study to show that experimentally asthmatic cats, but not control cats without airway inflammation, would have increased concentrations of ET in BALF.AnimalsEleven healthy, adult research cats.MethodsProspective experimental study. Six healthy cats without airway inflammation were used as controls. Asthma was induced using Bermuda grass allergen (BGA) in 5 cats. Collection of BALF for total nucleated cell and differential counts was performed. The concentration of ET‐1 in cell‐free BALF samples was determined. Data were analyzed using a Mann–Whitney U‐test with P < .05 considered significant.ResultsThe median [range] BALF total cell numbers, eosinophil numbers, and eosinophil percentages were significantly higher in the cats following experimental induction of asthma (1,870 cells/μL [1,450–3,440], 711 cells/μL [356–1,686] and 38% [20–49]) compared to baseline control parameters (462 cells/μL [239–780], 18 cells/μL [18–62] and 3.5% [0–8]) (P < .01). The median [range] BALF ET concentration was also significantly higher after induction of asthma (1.393 fmol/mL[0.977–2.247]) compared to healthy control cats (0.83250 fmol/mL [0.625–1.038]) (P = .012).Conclusions and Clinical ImportanceThis study suggests that BAL ET‐1 concentration can be used to differentiate normal cats from those with experimentally induced asthma. If the same holds true for cats with naturally developing asthma, BAL ET‐1 may prove a useful diagnostic biomarker for asthma.