bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nature and properties of carbohydrate derivatives of piperidin-4-one
Authors: Sarymzakova Roza , Ibragimova Ayzada , Sarymzakova Bermet , Khaperskaya Lydya , Sulyamanova Shafika 
Published: August 2024

In the modern world, drug resistance of pathogens responsible for various diseases has become a deadly threat to mankind, and requires the search for new biologically active substances. One of the approaches is the introduction of carbohydrates with unprotected hydroxyl groups into the structure of medical drugs, which can reduce their toxicity, increase their water solubility and increase the selectivity of action. The aim of the study was to develop a scientific basis for the synthesis of biologically active substances by condensation of glycosylvinylnitrosourea with various γ-piperidone derivatives and to study their properties. The choice of γpiperidone derivatives was justified by their strong antiviral and antibacterial activity. Despite their low water solubility, these compounds have potential for the development of new effective drugs. Experiments were carried out using various aglycones and carbohydrate components. A variety of methods including analytical, comparative, computer modelling and experimental methods were employed in this work to achieve the results. The results showed potentials in the proposed synthesis methods for the development of new drug compounds. The introduction of unprotected hydroxyl groups into the structure of the medicinal compounds by forming glycosyl carbamide bond improved the toxicological characteristics, solubility, and selectivity. It has been shown experimentally that the interaction of nitroso derivatives of glycosylurea with basic amines is relatively easy. This study opens prospects for the development of new drugs with improved properties and biological activity. The results of this work may lead to the development of effective therapeutic agents in the fight against drug resistance and infectious diseases.
Effet de la complémentation de la pousse d’<i>Euphorbia heterophylla</i> L. sur les principales hormones gonadotropes et sur les spermatozoïdes du cobaye
Authors: Kouame Francois Yao , Kouakou Vincent David N'goran , Djadji Lenoir Thierry Ayoman 
Published: August 2024

Euphorbia heterophylla est une adventice qui popularise 70% des parcelles cotonnières du nord de la Côte d’Ivoire. Une enquête, en vue de sa valorisation, a révélé ses effets profertiles. Dans le but de vérifier ces effets sur la fertilité du cobaye mâle, l’étude des activités fertilisantes de sa pousse sèche a été menée. A cet effet, une analyse du taux des hormones gonadotropes dans le sang après 15 jours, 30 jours et 60 jours de complémentation avec 5 g ou 10 g et des tests de motilité, vitalité, concentration et de formes des spermatozoïdes le 60ieme jour, ont été effectués après administration des traitements. Les résultats ont montré un effet propulseur sur la testostérone et la quantité et la qualité du sperme mais aucun effet sur la FSH, la LH et la prolactine. Pour une consommation d’environ 5 g ou 10 g par jour, le taux de testostérone a successivement augmenté. De plus, la complémentation a présenté une forte amélioration de la motilité, la vitalité, la motilité et la concentration des spermatozoïdes, et de leurs formes par rapport au témoin. Ces résultats montrent que la plante pourrait contribuer à l’amélioration des paramètres de reproduction des cobayes.

English title: Effect of Euphorbia heterophylla L. shoot supplementation on the main gonadotropic hormones and on guinea pig spermatozoaEuphorbia heterophylla is a weed which popularizes 70% of cotton plots in northern Ivory Coast. An investigation into its valuation revealed its profertile effects. In order to verify these effects on the fertility of male guinea pigs, the study of the fertilizing activities of its dry shoot was carried out. For this purpose, an analysis of the level of gonadotropic hormones in the blood after 15 days, 30 days and 60 days of supplementation with 5 g or 10 g and tests of motility, vitality, concentration and shape of the spermatozoa on the 60th day, were carried out. were carried out after administration of the treatments. The results showed a boosting effect on testosterone and sperm quantity and quality but no effect on FSH, LH and prolactin. For a consumption of around 5 g or 10 g per day, the testosterone level successively increased. In addition, the supplementation presented a strong improvement in the motility, vitality, motility and concentration of spermatozoa, and their shapes compared to the control. These results show that the plant could contribute to improving the reproductive parameters of guinea pigs.
Determinants of Information and Communication Technology Usage Among Cassava Value Chain Actors in Southwest, Nigeria
Authors: Oladipo Isaiah Fisayo , Ogunleye Kehinde Yewande , Olaniyi Olumuyiwa Akin , Dlamini Mbuyazwe Micheal 
Published: August 2024

This study investigated the determinants of information and communication technology usage among cassava value chain actors in Southwest Nigeria. The research focuses on identifying the factors influencing the use of ICT tools among cassava producers, marketers, and processors. Data were collected from 355 respondents using random and cluster sampling techniques and analysed through mean scores, frequency counts, percentages, and multiple regression. The most commonly used ICT tools among the actors are radio ( = = 2.92), mobile phones ( = = 2.80), and social media ( = 2.55), while global positioning systems (GPS) ( = = 0.34), and aerial drones = = 0.06) are among the least utilized. The finding revealed that the level of ICT usage among CVCAs in the region is relatively low. The result of multiple regression analysis indicates that sex, education level, household size, years of CVC experience, extension contacts, and membership in social organizations significantly influenced ICT usage among CVCAs. The study recommends that the extension institutions and relevant stakeholders should design and implement training programmes focused on enhancing the skills and capacity of cassava value chain actors (CVCAs) in utilizing modern ICT tools and harnessing their power for an efficient, and sustainable cassava value chain in Nigeria.
Effect of glycerol on preservation of Mycoplasma capricolum subsp. capripneumonia (Mccp) in frozen lung Samples
Authors: Adhiambo Onywera Ruth , Ouma Mungube Erick , Hezron Wesonga , Jane Ngaira , Nimmo Gicheru 
Published: August 2024

Mycoplasma capricolum subspecies capripneumoniae (Mccp) is the causative agent of contagious caprine pleuropneumonia (CCPP), a disease that affects the respiratory system of goats. Diagnosis of CCPP encounters challenges since Mccp is fastidious making it difficult to isolate or revive from stored samples. This study assessed the effect of glycerol on success of isolating Mccp from stored lung tissues. Experimentally infected goats developed fever and respiratory both consistent with CCPP and about 83% of the infected goats showed a variety of gross lesions including red hepatization, hyperemia, fibrinous pleural deposits and fibrinous adhesions. Three pieces of lung samples were collected from the same site of each of the 24 experimentally infected goats immediately after euthanasia. One piece was placed in media prepared with 8 weeks old serum immediately after collection for cultivation. The other two pieces were stored with and without glycerol at - 40℃. The stored samples were retrieved and cultured after 21, 34 and 39 months and the samples where Mccp was isolated re-cultured after six months. Mccp was not isolated in fresh lung samples. There was 50% (4/8) success in isolation of Mccp for lung samples stored in glycerol for 21 months compared to 37.5% (3/8) for those stored for 34 months. Out of the four lung samples which yielded Mccp at 21 months, Mccp was isolated in all four at 27 months, 3 samples at 34 months, and in no samples after 40 months of storage. At all-time points, samples stored without glycerol did not show growth. The findings demonstrate the effect of glycerol in preserving Mccp viability in longer duration periods storage. Further studies are needed to assess success of isolating Mccp using a single batch of quality-controlled serum, aliquoted and stored at different time intervals.
Do we think alike? Exploring user perceptions of road aesthetic dimensions in Nairobi
Authors: Ondieki Kemuma , Njuguna Mugwima , Gariy Abiero 
Published: August 2024

Road aesthetics is critical to improving safety, traffic flow, and user experience. This study hypothesises that these aesthetic qualities exist as latent factors in urban roads, influencing how people perceive them. The study aims to examine how different road users perceive these qualities. The study used a mixed-methods approach to collect data from 354 road users and identified coherence, naturalness, and imageability as the inherent aesthetic qualities in the roads. Different road user categories demonstrated distinct perceptions of the aesthetic dimensions. Regarding coherence, there was evidence of a difference in the perceptions by the types of road users; H(2) = 55.684, p  .001, among the categories of age groups; H(4) = 15.624, p = .004, and in the frequency of road use; H(2) = 9.006, p = .011. With regards to road naturalness, statistically significant differences were found between pedestrians and motorcyclists U(Npedestrians = 170, Nmotorcyclists = 87) = 3928.00, z = -6.170, p ˂ .001, as well as between pedestrians and drivers U(Npedestrians = 170, Ndrivers = 97) = 5963.00, z = -3.772, p ˂ .001. There was also evidence of a difference in male and female users, H(1) = 12.844, p < .001. Additionally, the one-way ANOVA showed a statistical difference among age groups, F(4,349) = 3.40, p=.010. Finally, the test results for road imageability indicated a difference in the types of road users, H(2) = 31.513, p < .001. It also revealed a statistical difference among groups based on the frequency of use F(2,305) =3.93, p=.021. These findings suggest differences in cognitive loads among different categories of road users and highlight the need to review how road users prioritise self-explaining road principles. The study proposes consideration of diverse user cognitive abilities as a major contributor to the human factors in the initial stages of road planning. This consideration will lead to more inclusive and effective road design strategies, ultimately resulting in safer urban roads.
The influence of transformational and transactional leadership styles on the implementation of strategic plans by devolved governments in Kenya
Authors: Gichuki Godfrey K. , Karanja Kabare , Atikiya Rukia 
Published: August 2024

Strategy implementation is only successful when backed by an effective leadership defined by how well leadership functions are carried out and how managers typically behave towards members of an organization. The purpose of the study was to investigate the influence of leadership styles on the implementation of strategic plans by devolved governments in Kenya. The study is anchored on Higgins's model of strategy implementation, and transformational and transactional theories of leadership. The study employed a cross-sectional descriptive survey research design. The target population was the 47 devolved governments in Kenya represented by the five devolved units in the Nairobi Metropolitan area comprising of Nairobi Kiambu, Murang’a, Machakos and Kajiado. A stratified random sampling technique was applied to Yamane’ formula to select 217 respondents from 474 senior county officers the five counties. Data was collected using a semi-structured, self-administered questionnaire. A pilot test was carried out to assess the reliability and validity of the data collection instrument. Descriptive data analysis and inferential statistics were produced using SPSS and presented in figures and tables. Qualitative data collected using the open-ended questions was transformed into quantitative data by use of content analysis. The study findings revealed that the transformational leadership style had a positive and significant influence on strategy implementation while the transactional leadership style had a negative and insignificant influence on strategy implementation by the devolved governments in Kenya. The study found other factors such as lack of prioritization of projects, lack of public participation and feedback and political interference were important. The study therefore provides empirical evidence in evaluating transformational and transactional leadership styles, adds valuable insights on how to improve strategic management practice, and presents recommendation for leadership policy development by devolved government and options for future research studies.
Assessment of Heavy Metals and Pesticide Residues in Abelmoschus esculentus (Okro), Amaranthus cruentus (Spinach), Hibiscus sabdariffa (Roselle) and Cabbage Vegetables from Agricultural Area of Boronji Jimeta, Adamawa State, Nigeria
Authors: Micah M. M. , Peace Z. , Usaku R. , Onyebuchi P. U. 
Published: August 2024

Although green leafy vegetables are a great source of micronutrients, they can also often include harmful heavy metals and pesticides. Hence, the objective of this paper was to assess the levels of heavy metals and pesticide residues in Abelmoschus esculentus (Okra), Amaranthus cruentus (Spinach), Hibiscus sabdariffa (Roselle) and Cabbage vegetable samples from Agricultural Area of Boronji Jimeta, Adamawa State, Nigeria using Atomic Adsorption Spectroscopy (AAS) and gas chromatography/mass spectrometry (GC-MS) respectively. Result show that the detected heavy metals include Cd, Cr, Pb, Zn, and Cu whereas pesticide residues include Dichlorvos, Dimethoate, Chlorpyrifos Lambda.-Cyhalothrin and Imdacloprid. The concentration of Cd 0.62mg/kg, 0.47mg/kg, 0.56mg/kg and 1.93mg/kg in spinach, Roselle, okra and Cabbage. Pb 0.60mg/kg, 0.35mg/kg and 0.32mg/kg in spinach, Roselle, and okra and pesticide residues in Dimethoate in cabbage 0.202mg/kg and Lambda.-Cyhalothrin 0.067mg/kg and Chlorpyrifos 0.195mg/kg in okra were found to be above the establish permissible limit. Pesticide residues and heavy metal levels fluctuated, showing distinct patterns even though they were mostly below the established maximum permissible limit. These heavy metals and pesticide residues can be harmful to human health, especially if consumed in excess. They can come from both naturally occurring and man-made sources.
PENGARUH HARGA DAN PELAYANAN TERHADAP KEPUASAN KONSUMEN PADA CV. VIORA CONSULTANT DI MEDAN
Authors: Sahputri Balqis , Nasution Muhammad Amri , Zulkarnain Mierna 
Published: August 2024

Dalam perusahaan jasa berfokus pada jasa yang akan mereka jual kepada konsumen yang memerlukan, perusahaan jasa atau sering disebut perusahaan penyedia layanan jasa menawarkan suatu keahlian tertentu yang dapat memberikan manfaat kepada konsumen sebagai pengguna jasa tersebut. Tujuan perusahaan jasa sendiri yaitu untuk memperoleh keuntungan atau laba. Tujuan penelitian ini adalah untuk mengetahui pengaruh harga terhadap kepuasan konsumen pada perusahaan study tour CV. Viora consultant di Medan. Untuk mengetahui pengaruh pelayanan terhadap kepuasan konsumen pada perusahaan study tour CV. Viora Consultant di Medan. Untuk mengetahui pengaruh harga dan pelayanan terhadap kepuasan konsumen pada CV. Viora Consultant di Medan. Teknik analisis data yang digunakan adalah uji reliabilitas, uji normalisasi dan regresi linier berganda. Sampel yang diteliti sebanyak 30 responden. Hasil penelitian uji t diperoleh(4,848>2,04) (Sig 0.001 < α0.05) sehingga dapat disimpulkan harga berpengaruh terhadap keputusan pembelian. Hasil penelitian uji t diperoleh (5,899>2,04) (Sig 0.000 < α0.05) sehingga dapat disimpulkan pelayanan berpengaruh terhadap keputusan pembelian.Artinya dengan mengenal pelayanan perusahaan konsumen tersebut menikmati pelayanan tersebut karena kualitas. Hasil penelitian uji F diperoleh (50,785> 3,13) (Sig. 0.000 < α0.05)harga dan pelayananberpengaruh terhadap keputusan pembelian. Artinya dengan bersama-sama harga dan pelayanan berpengaruh nyata terhadap keputusan pembelian. Dari hasil R dapat dilihat bahwa 0.600 dan hal ini menyatakan bahwa variable pengaruh harga dan pelayanan sebesar 0.600. Nilai R-Square sebesar 0.359 atau 35,9% keputusan pembelian sisanya dipengaruhi oleh faktor lain atau variable lain
Sosialisasi Anti-Bullying dengan Metode Kreatif Sebagai Upaya Peningkatan Pemahaman Dan Perilaku Baik Siswa Di MI Muhammadiyah Kota Madiun
Authors: Istighfarin Awit , Aini Dyta Noor , Khudin Mifta 
Published: August 2024

Program pengabdian masyarakat ini bertujuan untuk meningkatkan pemahaman dan perilaku baik siswa terhadap bullying melalui sosialisasi anti-bullying dengan metode kreatif di MI Muhammadiyah Kota Madiun. Bullying merupakan masalah serius yang dapat mempengaruhi kesejahteraan psikologis dan akademik siswa. Pendekatan konvensional dalam sosialisasi sering kali kurang efektif dalam menarik perhatian dan keterlibatan siswa. Oleh karena itu, program ini mengadopsi metode kreatif seperti bernyanyi, bercerita, dan bermain game untuk menyampaikan pesan anti-bullying dengan cara yang lebih menarik dan interaktif. Metode dalam pengabdian ini mencakup observasi lapangan, perencanaan sosialisasi, dan pelaksanaan sosialisasi. Hasil dari program ini memiliki dampak positif pada peningkatan pemahaman siswa mengenai bullying setelah mengikuti sosialisasi dengan metode kreatif. Metode kreatif cukup efektif dalam meningkatkan keterlibatan siswa dan menciptakan suasana belajar yang menyenangkan. Program ini membuktikan bahwa sosialisasi anti-bullying dengan metode kreatif dapat menjadi solusi yang efektif dalam meningkatkan pemahaman dan perilaku baik siswa terhadap bullying
UJI EFEKTIVITAS PLANT GROWTH PROMOTING RHIZOBACTERIA (PGPR) DARI AKAR BAMBU KUNING (BAMBUSA SP.) UNTUK PERTUMBUHAN DAN PRODUKSI TANAMAN KACANG TANAH (ARACHIS HYPOGAEA VAR) PADA MEDIA GAMBUT
Authors: Riono Yoyon , Marlina Marlina 
Published: August 2024

Abstract
This research is entitled TESTING THE EFFECTIVENESS of Plant Growth Promoting Rhizobacteria (PGPR) FROM YELLOW BAMBOO ROOTS (Bambusa sp.) FOR THE GROWTH AND PRODUCTION OF PEANUT PLANTS (Arachis hypogaea var) ON PEAT MEDIA. The aim of this research was to determine the growth and production of peanut plants with different doses of PGPR. This research was conducted from August to November 2023 with a non-factorial Randomized Block Design (RAK). Namely the PGPR dose consisting of 0 ml/L (P0), 10 ml/L (P1), 20 ml/L (P2), 30 ml/L (P3), 40 ml/L (P). The parameters observed were the increase in plant height, average flowering age, number of pods per plant, and weight of 100 grains. The results showed that the best treatment was a PGPR concentration of 40 ml/L which had a significant to very significant effect on the parameters of plant height increase, average flowering age, wet weight of pods per plant, and weight of 100 seeds.

Penelitian ini berjudul UJI EFEKTIVITAS Plant Growth Promoting Rhizobacteria (PGPR) DARI AKAR BAMBU KUNING (Bambusa sp.) UNTUK PERTUMBUHAN DAN PRODUKSI TANAMAN KACANG TANAH (Arachis hypogaea var) PADA MEDIA GAMBUT. Tujuan dari penelitian ini adalah untuk mengetahui pertumbuhan dan produksi tanaman kacang tanah dengan perbedaan dosis PGPR. Penelitian ini dilaksanakan pada bulan Agustus sampai November 2023 dengan Rancangan Acak Kelompok (RAK) nonfaktorial. Yaitu dosis PGPR yang terdiri dari 0 ml/L (P0), 10ml/L (P1), 20 ml/L (P2), 30 ml/L (P3), 40 ml/L (P). Parameter yang diamati adalah pertambahan tinggi tanaman, umur berbunga rata-rata, jumlah polong per tanaman, bobot 100 butir. Hasil penelitian menunjukkan bahwa perlakuan terbaik adalah konsentrasi PGPR 40 ml/L yang memberikan pengaruh nyata sampai sangat nyata pada parameter pertambahan tinggi tanaman, umur berbunga rata-rata, berat basah polong per tanaman dan bobot 100 biji
PENYERAPAN TENAGA KERJA INDUSTRI MIKRO KECIL DAN PENURUNAN TINGKAT KEMISKINAN: BUKTI DATA PANEL DI PROVINSI RIAU
Authors: Arifin Muhammad , Amri Khairul 
Published: August 2024

This study aims to analyze the impact of labor absorption in the micro and small industrial (IMK) sector on poverty levels in Riau province. The data used is in the form of panel data from 12 districts/cities over the period 2018-2020. The data is then analyzed using an econometric panel regression model. The study finds that labor absorption in this industrial sector has a negative and significant effect on poverty levels. The greater the labor absorption in the IMK sector, the lower the poverty level in Riau province. Conversely, the smaller the labor absorption, the higher the poverty level. The results of this study provide implementable policy recommendations that efforts to reduce poverty levels in Riau province can be carried out through policies related to the development of micro and small industries in the community.

Penelitian ini bertujuan untuk menganalisis pengaruh penyerapan tenaga kerja sektor industri mikro kecil (IMK) terhadap tingkat kemiskinan di provinsi Riau. Data yang digunakan berbentuk data panel 12 kabupaten kota selama periode 2018-2020. Selanjutnya data dianalisis menggunakan model ekonometrik regresi panel. Penelitian menemukan bahwa penyerapan tenaga kerja pada sektor industri ini berpengaruh negatif dan signifikan terhadap tingkat kemiskinan. Semakin besar penyerapan tenaga kerja di sektor IMK, semakin rendah tingkat kemiskinan di provinsi Riau. Sebaliknya, semakin kecil penyerapan tenaga kerja semakin tinggi tingkat kemiskinan. Hasil penelitian ini memberikan rekomendasi implementatif bahwa upaya penurunan tingkat kemiskinan di provinsi Riau dapat dilakukan melalui kebijakan yang berkaitan dengan pengembangan industri mikro kecil di masyarakat.
Penguatan Toleransi Melalui Implementasi Budaya Sekolah Religius: Studi Kasus SDN di Jakarta Timur
Authors: Amirullah Amirullah , Nurhalimah Nurhalimah , Wisudiyantie Nurma Dwi , Oktafiani Oktafiani 
Published: August 2024

Intoleransi menjadi masalah dan tantangan di tengah masyarakat majemuk seperti bangsa Indonesia. Sikap intoleransi adalah bukanlah bawaan tapi dibentuk oleh banyak faktor termasuk faktor lingkungan pendidikan. Penguatan toleransi sejak usia dini dan sekolah dasar dinilai penting. Penelitian ini bertujuan untuk mengetahui penguatan sikap toleransi peserta didik melalui implementasi lingkungan budaya sekolah religius dengan integrasi nilai Islam dan Kristen di SDN Ciracas 03 Jakarta. Penelitian ini merupakan penelitian studi kasus dengan menggunakan metode analisis kualitatif deskriptif dan didukung dengan data kuantitatif melalui data angket. Teknik pengumpulan data pada penelitian ini adalah dengan melalui pengamatan dan kuesioner angket yang telah dilakukan pengujian validasi dengan rumus korelasi product moment dan pengujian reliabilitas dengan rumus alpha cronbach. Hasil penelitian ini menunjukkan bahwa lingkungan budaya sekolah religius yang menekankan implementasi nilai-nilai toleransi berpengaruh pada sikap toleransi siswa/i di SDN Ciracas 03. Interaksi siswa Muslim dan Kristen yang berbeda agama membuat mereka semakin terbuka dan tidak saling berprasangka karena perbedaan agama. Kesimpulan ini diperkuat oleh data kuantitatif kami yang menunjukkan bahwa sebesar 87 % siswa/i bersikap terbuka dalam perbedaan, 90% bersikap saling menghargai satu sama lain, 84% siswa/i bersikap peduli terhadap perbedaan, 94% bersikap mengakomodasi keberagaman beragama, dan 83% menyatakan sikap kenyaman dalam perbedaan. Penelitian ini memperkuat pandangan dan merekomendasikan perlunya implementasi lingkungan budaya religius yang berlandaskan pada nilai-nilai toleransi dalam memperkuat sikap toleransi pada siswa/i sekolah dasar di Indonesia.