bluuebunny/crossref_metadata_2025_split huggingface dataset:
Delayed Laparotomy After Selective Non‐operative Management of Penetrating Abdominal Injuries
Authors: Peev Miroslav P. , Chang Yuchiao , King David R. , Yeh Daniel D. , Kaafarani Haytham , Fagenholz Peter J. , De Moya Marc A. , Velmahos George C. 
Published: October 2014

AbstractBackgroundMain concern during the practice of selective non‐operative management (SNOM) for abdominal stab wounds (SW) and gunshot wounds (GSW) is the potential for harm in patients who fail SNOM and receive a delayed laparotomy (DL). The aim of this study is to determine whether such patients suffer adverse sequelae because of delays in diagnosis and treatment when managed under a structured SNOM protocol.Methods190 patients underwent laparotomy after an abdominal GSW or SW (5/04–10/12). Patients taken to operation within 120 min of admission were included in the early laparotomy (EL) group (n =153, 80.5 %) and the remaining in the DL group (n =37, 19.5 %). Outcomes included mortality, hospital stay, and postoperative complications.ResultsThe median time from hospital arrival to operation was 43 min (range: 17–119) for EL patients and 249 min (range: 122–1,545) for DL patients. The average number and type of injuries were similar among the groups. Mortality and negative laparotomy were observed only in the EL group. There was no significant difference in the hospital stay between the groups. The overall complications were higher in the EL group (44.4 vs. 24.3 %, p =0.026). DL was independently associated with a lower likelihood for complications (OR 0.39, 95 % CI 0.16–0.98, p =0.045). Individual review of all DL patients did not reveal an incident in which complications could be directly attributed to the delay.ConclusionsIn a structured protocol, patients who fail SNOM and require an operation are recognized and treated promptly. The delay in operation does not cause unnecessary morbidity or mortality.
Behandlung einer serösen makulären Netzhautablösung mit Antihistaminika
Authors: Kirschfeld K. 
Published: October 2014

Zusammenfassung
Die Ätiologie der Netzhautablösungen bei Chorioretinopathia centralis serosa (CCS) ist unbekannt. Von 3 Tatbeständen wird aber ausgegangen: 1) dass der Abhebung der Rezeptor/Pigmentepithel-Schicht durch ein seröses Exsudat eine Hyperpermeabilität der Choriokapillaren zugrunde liegt; 2) dass betroffene Patienten häufig unter Kopfschmerzen leiden; 3) dass die Erkrankung durch Stress begünstigt wird. Eine erhöhte Histaminkonzentration im Blutplasma könnte zu den genannten Konsequenzen führen. Dies führte zur Hypothese, dass Histamin an der Entstehung der CCS beteiligt sein könnte. Nach Einnahme des Antihistaminikums Loratadin erfolgten innerhalb 1 Woche ein deutlicher Abbau des retinalen Exsudats sowie die Wiederherstellung des Sehvermögens. Dies stützt die Hypothese, dass Histamin an der Entstehung von Netzhautablösungen beteiligt sein könnte. Weitere Untersuchungen müssen klären, ob diese Hypothese zutrifft und ob Antihistaminika womöglich auch bei Makuladegeneration (AMD) eingesetzt werden können.
Dimensional Analysis of the Distal Phalanx with Consideration of Distal Interphalangeal Joint Arthrodesis Using a Headless Compression Screw
Authors: Darowish Michael , Brenneman Rodney , Bigger Justin 
Published: October 2014

Background Headless compression screws have been used for arthrodesis of the distal interphalangeal joint with good clinical results. However, some distal phalanges are too small, thus precluding their use, or increasing complication rates. Methods In order to validate our digital measurements, radiographs of five cadaveric hands were obtained. The distal phalanges of these fingers were measured using our institution's digital radiograph software. The cadavers were then dissected, and the actual phalanges were measured to confirm the accuracy of the digital measurements; 200 consecutive hand radiographs were then measured to obtain average width and heights of the narrowest measurements of the distal phalanx of each finger. Subgroup analysis of each finger for age and gender was completed. Results and Conclusions Females were routinely smaller than their male counterparts. No age-related differences were seen. A substantial number of fingers were found to be too small to allow for use of headless compression screws; 42 % of small finger distal phalanges are too small to accommodate 2.8-mm threads, and that number increases to 81 % with 3.2-mm threads and 97 % with 3.5-mm threads. Few distal phalanges, regardless of which finger, are large enough to accommodate 3.5-mm-diameter threads; 22% of female ring finger distal phalanges are smaller than 2.8 mm, and 66 % of ring fingers are smaller than 3.2 mm. Based on our measurements, a surprising number of distal phalanges are smaller than the trailing thread diameter of commonly commercially available headless screws. Care must be taken in selecting implants for distal interphalangeal (DIP) fusion.
Trends in Mortality Decrease and Economic Growth
Authors: Niu Geng , Melenberg Bertrand 
Published: October 2014

AbstractThe vast literature on extrapolative stochastic mortality models focuses mainly on the extrapolation of past mortality trends and summarizes the trends by one or more latent factors. However, the interpretation of these trends is typically not very clear. On the other hand, explanation methods are trying to link mortality dynamics with observable factors. This serves as an intermediate step between the two methods. We perform a comprehensive analysis on the relationship between the latent trend in mortality dynamics and the trend in economic growth represented by gross domestic product (GDP). Subsequently, the Lee-Carter framework is extended through the introduction of GDP as an additional factor next to the latent factor, which provides a better fit and better interpretable forecasts.
Additional intranasal oxytocin to escitalopram improves depressive symptoms in resistant depression: An open trial
Authors: Scantamburlo G. , Hansenne M. , Geenen V. , Legros J.J. , Ansseau M. 
Published: October 2014

AbstractThe aim of this open trial was to assess the antidepressant/anxiolytic effects of oxytocin used as an adjunct to antidepressant in treatment-resistant depression. Fourteen patients, who have not responded to 40 mg of escitalopram, received intranasal synthetic oxytocin during 4 weeks, in association with antidepressant. This is the first open trial study suggesting OT in association with escitalopram significantly reduced scores on Hamilton Depression Rating Scale.
Lake Level Reconstruction for 12.8–2.3 ka of the Ngangla Ring Tso Closed-Basin Lake System, Southwest Tibetan Plateau
Authors: Hudson Adam M. , Quade Jay , Huth Tyler E. , Lei Guoliang , Cheng Hai , Edwards Lawrence R. , Olsen John W. , Zhang Hucai 
Published: October 2014

AbstractWe present a shoreline-based, millennial-scale record of lake-level changes spanning 12.8–2.3 ka for a large closed-basin lake system on the southwestern Tibetan Plateau. Fifty-three radiocarbon and eight U–Th series ages of tufa and beach cement provide age control on paleoshorelines ringing the basin, supplemented by nineteen ages from shell and aquatic plant material from natural exposures generally recording lake regressions. Our results show that paleo-Ngangla Ring Tso exceeded modern lake level (4727 m asl) continuously between ~ 12.8 and 2.3 ka. The lake was at its highstand 135 m (4862 m asl) above the modern lake from 10.3 ka to 8.6 ka. This is similar to other closed-basin lakes in western Tibet, and coincides with peak Northern Hemisphere summer insolation and peak Indian Summer Monsoon intensity. The lake experienced a series of millennial-scale oscillations centered on 11.5, 10.8, 8.3, 5.9 and 3.6 ka, consistent with weak monsoon events in proxy records of the Indian Summer Monsoon. It is unclear whether these events were forced by North Atlantic or Indian Ocean conditions, but based on the abrupt lake-level regressions recorded for Ngangla Ring Tso, they resulted in significant periodic reductions in rainfall over the western Tibetan Plateau throughout the Holocene.
MARITAL ALLIANCES AND AFFINAL RELATIVES (SHENG甥 ANDHUNGOU婚購) IN THE SOCIETY AND POLITICS OF ZHOU CHINA IN THE LIGHT OF BRONZE INSCRIPTIONS
Authors: Khayutina Maria 
Published: October 2014

AbstractSeveral hundred inscribed bronze objects dating from Western and Eastern Zhou periods were commissioned for or by married women. Several dozen inscriptions are known whose commissioners called themselvessheng生 (甥) of a number of lineages. In pre-Qin Chinese, the termsheng甥 designated several categories of affinal relatives: paternal aunts’ sons, maternal uncles’ sons, wives’ brothers, sisters’ husbands, and sons of sisters or daughters. The wide geographical and chronological spread of female- orsheng-related vessels, as well as dedications to “many affinal relatives” (hungou婚購) in bronze inscriptions point to the importance of marital ties in early Chinese society and politics.Focusing on the inscriptions commissioned bysheng, the present article suggests that even when concluded at a considerable distance, marriages produced long-term mutual obligations for male members of the participating lineages or principalities. Affinal relationships represented social and political capital that could be converted in terms of individuals’ careers and prestige or benefits for their whole lineages/states. In sum, starting from the early Western Zhou period, marital alliances represented a substantial integrative factor in early Chinese politics. On the one hand, marital alliances helped to consolidate the radial network of Zhou states centered on the Zhou king. On the other hand, they facilitated the construction of decentralized regional and interregional inter-state networks. The latter guaranteed the stability of the Zhou political system even when it had a weak center. As a result, the Zhou networks did not fall apart following crises in the Zhou royal house, but continued to expand by the inclusion of new members.
Iodine intake and status of UK women of childbearing age recruited at the University of Surrey in the winter
Authors: Bath Sarah C. , Sleeth Michelle L. , McKenna Marianne , Walter Alan , Taylor Andrew , Rayman Margaret P. 
Published: October 2014

As intra-thyroidal iodine stores should be maximised before conception to facilitate the increased thyroid hormone production during pregnancy, women who are planning to become pregnant should ideally consume 150 μg iodine/d (US RDA). As few UK data exist for this population group, a cross-sectional study was carried out at the University of Surrey to assess the iodine intake and status of women of childbearing age. Total iodine excretion was measured from 24 h urine samples in fifty-seven women; iodine intake was estimated by assuming that 90 % of ingested iodine was excreted. The average iodine intake was also estimated from 48 h food diaries that the participants completed. The median urinary iodine concentration value (63·1 μg/l) indicated the group to be mildly iodine deficient by WHO criteria. By contrast, the median 24 h urinary iodine excretion value (149·8 μg/24 h) indicated a relatively low risk of iodine deficiency. The median estimated iodine intake, extrapolated from urinary excretion, was 167 μg/d, whereas it was lower, at 123 μg/d, when estimated from the 48 h food diaries. Iodine intake estimated from the food diaries and 24 h urinary iodine excretion were strongly correlated (r 0·75, P< 0·001). The intake of milk, eggs and dairy products was positively associated with iodine status. The iodine status of this UK cohort is probably a best-case scenario as the women were mostly nutrition students and were recruited in the winter when milk-iodine content is at its highest; further study in more representative cohorts of UK women is required. The present study highlights the need for revised cut-off values for iodine deficiency that are method- and age group-specific.
Influence of exogenous enzymes in presence ofSalix babylonicaextract on digestibility, microbial protein synthesis and performance of lambs fed maize silage
Authors: VALDES K. I. , SALEM A. Z. M. , LOPEZ S. , ALONSO M. U. , RIVERO N. , ELGHANDOUR M. M. Y. , DOMÍNGUEZ I. A. , RONQUILLO M. G. , KHOLIF A. E. 
Published: October 2014

SUMMARYSixteen Suffolk lambs with 29 ± 2·0 kg body weight were housed in individual cages for 60 days and allotted to four treatments in a completely randomized design to determine the effect of administration ofSalix babylonica(SB) extract and/or exogenous enzymes (ZADO®) on lamb performance. Lambs were fed with 300 g/kg concentrate (160 g crude protein (CP)/kg, 13·4 MJ metabolizable energy (ME)/kg dry matter (DM)) and 700 g/kg maize silage (80 g/kg CP, 11·7 MJ ME/kg DM) as a basal diet (control). Another three treatments were tested; the SB extract was administered at 30 ml/day (SB) and exogenous enzymes ZADO®(i.e. an exogenous enzyme cocktail in a powder form) directly fed at 10 g/day (EZ), while the last treatment contained ZADO®at 10 g/day + SB extract at 30 ml/day (EZSB). Lambs of the treatment EZSB had the greatest average daily weight gain (ADG) and feed conversion throughout the period of the experiment. However, during the first 30 days SB was more effective for ADG than EZ andvice versaduring the last 30 days of the experiment. Water consumption was greater for SB, followed by EZ and EZSB compared to the control. Intakes of DM and organic matter (OM) were the highest in EZSB followed by EZ, which had the greatest neutral detergent fibre, acid detergent fibre (ADF) and nitrogen (N) intakes. The EZSB treatment had the greatest DM and OM digestibilities compared to the other treatments; however, SB had the greatest ADF digestibility. Combination of EZ and SB had the best N balance. Allantoin, total purine derivatives (PD), allantoin : -creatinine ratio, and PD : creatinine ratio were increased in EZSB compared to the other treatments. However, EZ supplementation increased uric acid concentration, whereas the microbial N (g N/day) and metabolizable protein (g N/day) were increased in EZSBversusthe other treatments. It can be concluded that addition of 10 g ZADO®in combination withS. babylonicaextract at 30 ml/day in the diet of lambs increased feed intake, nutrient digestibility and daily gain, with a positive impact on the use of N and microbial protein synthesis.
Estimation of wheat nitrogen status under drip irrigation with canopy spectral indices
Authors: JIN X. L. , DIAO W. Y. , XIAO C. H. , WANG F. Y. , CHEN B. , WANG K. R. , LI S.-K. 
Published: October 2014

SUMMARYCrop nitrogen (N) status is an important indicator of crop health and predictor of subsequent crop yield. The present study was conducted to analyse the relationships between nitrogen nutrition index (NNI), nitrogen biomass difference (ΔNB) and spectral indices in wheat, and then attempt to improve field N management. Spectral indices and concurrent sample N and biomass parameters were obtained from the Shihezi University experimental site in Xinjiang, China during 2009 and 2010. The results showed that all spectral indices were significantly correlated with NNI. Regression functions with the highest determination coefficient (R2) and the lowest root mean square error (RMSE) were used to improve prediction of NNI, and then the selected spectral index was used to estimate NNI and ΔNB. The strongest relationships were observed for the products of modified normalized difference 705 × biomass dry weight (BND705) and the enhanced vegetation index 2 (EVI2) for estimating NNI. There were also strong relationships between the NNI and the normalized NNI (ΔNNI) as well as between ΔNNI and ΔNB, with a linear relationship between ΔNB and the spectral index BND705 and a linear relationship between ΔNB and the spectral index EVI2. These results indicated that BND705 and EVI2 can be used to improve the accuracy of NNI estimation, and the correlations of ΔNB and NNI with BND705 and EVI2 can be used to further improve field N management in wheat.
Construction and evaluation of a chimeric protein made fromFasciola hepaticaleucine aminopeptidase and cathepsin L1
Authors: Hernández-Guzmán K. , Sahagún-Ruiz A. , Vallecillo A.J. , Cruz-Mendoza I. , Quiroz-Romero H. 
Published: October 2014

AbstractLeucine aminopeptidase (LAP) and cathepsin L1 (CL1) are important enzymes for the pathogenesis and physiology ofFasciola hepatica. These enzymes were analysedin silicoto design a chimeric protein containing the most antigenic sequences of LAP (GenBank; AAV59016.1; amino acids 192–281) and CL1 (GenBank CAC12806.1; amino acids 173–309). The cloned 681-bp chimeric fragment (rFhLAP-CL1) contains 270 bp from LAP and 411 bp from CL1, comprising three epitopes, DGRVVHLKY (amino acids 54–62) from LAP, VTGYYTVHSGSEVELKNLV (amino acids 119–137) and YQSQTCLPF (amino acids 161–169) from CL1. The ~25 kDa rFhLAP-CL1 chimeric protein was expressed from the pET15b plasmid in the Rosetta (DE3)Escherichia colistrain. The chimeric protein rFhLAP-CL1, which showed antigenic and immunogenic properties, was recognized in Western blot assays usingF. hepatica-positive bovine sera, and induced strong, specific antibody responses following immunization in rabbits. The newly generated chimeric protein may be used as a diagnostic tool for detection of antibodies againstF. hepaticain bovine sera and as an immunogen to induce protection against bovine fasciolosis.
Diversity of nematodes in the yellow-necked field mouseApodemus flavicollisfrom the Peripannonic region of Serbia
Authors: Čabrilo B. , Jovanović V.M. , Bjelić-Čabrilo O. , Budinski I. , Blagojević J. , Vujošević M. 
Published: October 2014

AbstractUp to six nematode species were identified from 86 specimens of the yellow-necked field mouseApodemus flavicollisfrom three mountainous localities known as Avala, Cer and Liškovac in Serbia. The highest prevalence of infection of 97% was recorded from Mt. Avala. Only one nematode species,Syphacia frederici, occurred in all three localities. There was complete overlap in nematode species from Mts. Avala and Liškovac, whereas the taxonomic distinctness of Mt. Cer was seen in the presence of the insect-transmitted speciesRictularia proni. Locality was a statistically significant factor in all the best-fitted generalized linear models of variation in abundances. The highest level of both species richness and parasite alpha diversity (Shannon'sH= 1.47) was found in the easternmost Mt. Liškovac, whereas the diversity indices were lowest for the westernmost Mt. Cer (Shannon'sH= 0.48). In view of this geographical difference, the beta diversity indices were calculated along a west to east longitudinal gradient.
Stray animal and human defecation as sources of soil-transmitted helminth eggs in playgrounds of Peninsular Malaysia
Authors: Mohd Zain S.N. , Rahman R. , Lewis J.W. 
Published: October 2014

AbstractSoil contaminated with helminth eggs and protozoan cysts is a potential source of infection and poses a threat to the public, especially to young children frequenting playgrounds. The present study determines the levels of infection of helminth eggs in soil samples from urban and suburban playgrounds in five states in Peninsular Malaysia and identifies one source of contamination via faecal screening from stray animals. Three hundred soil samples from 60 playgrounds in five states in Peninsular Malaysia were screened using the centrifugal flotation technique to identify and determine egg/cyst counts per gram (EPG) for each parasite. All playgrounds, especially those in Penang, were found to be contaminated with eggs from four nematode genera, withToxocaraeggs (95.7%) the highest, followed byAscaris(93.3%),Ancylostoma(88.3%) andTrichuris(77.0%). In addition, faeces from animal shelters were found to contain both helminth eggs and protozoan cysts, with overall infection rates being 54% and 57% for feline and canine samples, respectively. The most frequently occurring parasite in feline samples wasToxocara cati(37%; EPG, 42.47 ± 156.08), while in dog faeces it wasAncylostomasp. (54%; EPG, 197.16 ± 383.28). Infection levels also tended to be influenced by season, type of park/playground and the texture of soil/faeces. The occurrence ofToxocara,AncylostomaandTrichuriseggs in soil samples highlights the risk of transmission to the human population, especially children, while the presence ofAscariseggs suggests a human source of contamination and raises the issue of hygiene standards and public health risks at sites under investigation.
Synovial sarcoma of the ethmoidal sinus
Authors: Wong H-T , Ho C-Y , Nazarina A R , Prepageran N 
Published: October 2014

AbstractBackground:Synovial sarcoma is a high-grade, soft tissue, malignant disease associated with poor outcome. Typically, synovial sarcoma involves the extremities, with less than 10 per cent of cases occurring in the head and neck region. Synovial sarcoma of the paranasal sinuses is a rare entity. This paper presents a case of an elderly patient with synovial sarcoma of the ethmoidal sinus.Case report:An 80-year-old woman who had right epistaxis underwent nasal endoscopy and biopsy. The pathology indicated synovial sarcoma and the patient underwent endoscopic excision of the tumour.Conclusion:Synovial sarcoma of the ethmoidal sinus is very rare. Patients should undergo excision of the tumour with post-operative radiotherapy. However, the prognosis remains poor and usually the patient succumbs to death within a year.
Nebulised N-acetylcysteine used in acute tracheostoma obstruction
Authors: Patel A , Theokli C 
Published: October 2014

AbstractBackground:Patients with laryngectomy tracheostomas are at risk of developing acute airway obstruction due to mucous crusting. Current management relies on saline nebulisers, followed by suction and manual evacuation to remove the obstruction. This paper describes the first reported case of using N-acetylcysteine nebulisers in addition to saline to adequately soften the mucous plugs in order to facilitate removal.Case report:A 68-year-old female attended the emergency department with a partial obstruction of her laryngectomy tracheostoma as a result of mucous crusting. Saline nebulisers did not provide adequate softening to allow the obstructing mucous plugs to be removed. N-acetylcysteine nebulisers were used to further soften the mucous plugs which successfully resulted in their removal.Conclusion:N-acetylcysteine nebulisers can be used to assist in the removal of mucous plugs in saline-resistant cases.