bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Self‐Calibrating Sensing Platform Based on Amine‐Responsive Excitation Wavelength‐Dependent Fluorescent Polymers for Real‐Time and Visual Detection of Food Freshness
Authors: Zhang Qi , Yu Lan , Han Weiqiang , Yang Li , Li Hongjuan , Sun Shiguo , Xu Yongqian 
Published: August 2024

AbstractAccurate assessment of food freshness is critical to maintaining human health. However, the complex environment of food usually leads to false‐positive measurements result. Therefore, the development of sensing platforms with self‐calibration for accurate detection of food freshness in complex environments is essential. Here, using the green fluorescence‐emitting FITC‐ene and the red fluorescence‐emitting DBA‐ene‐Eu3+ as fluorescent units, fluorescent polymeric materials P1‐P4 with excitation wavelength‐dependent (254 and 365 nm, matched with standard UV lamp) emission are prepared. P1‐P4 responded rapidly to biogenic amines (BAs). Among them, P3 exhibits the widest linear range, and the most noticeable fluorescence color change (from orange‐red to yellow‐green) under 254 nm excitation and enhanced green fluorescence under 365 nm excitation. The changes of P3‐prepared labels at different excitation wavelengths can be utilized to rapidly evaluate the food's freshness. Furthermore, by using a smartphone to read the Red/Green/Blue values of the labels, the total volatile basic nitrogen (TVBN) values can be output to quantitatively evaluate the food freshness, and the output TVBN values at different excitation wavelengths are utilized for mutual calibration to improve the accuracy of the estimation results. This self‐calibrating sensing platform is fast and nondestructive, which provides an effective method for the accurate evaluation of food freshness.
Optimized Electrode/Electrolyte Interface Engineering for Dendrite‐Free Al Anode and Self‐Activated Graphite Cathode
Authors: Xie Yuehong , Meng Yi , Liu Mingxia , Wang Shixin , Guo Yuan , Liang Zhongshuai , Du Xianfeng 
Published: August 2024

AbstractRechargeable aluminum batteries (RABs) have garnered attention owing to their impressive theoretical capacity, outstanding safety features, and abundant Al reserves, thereby positioning them as a potential alternative and supplement to fixed energy storage. Nonetheless, RABs still suffer from issues, such as poor anode stability stemming from the corrosivity of the chloral aluminate ionic liquid electrolyte (ILs) and subpar wettability of the cathode. To address these issues, the proposed electrolyte interfacial engineering involves the nonionic surfactant (F127) as an interfacial optimizer in ILs, simultaneously modulating the anode–electrolyte and cathode–electrolyte interfaces. Systematic experiments and theoretical analyses validate that F127 preferentially adsorbs on the electrode surface, forming a dense and uniform adsorption layer. The F127 layer can effectively mitigate the corrosion of ILs on the Al anode and regulate the current density to achieve uniform Al deposition. Furthermore, F127 enhances the wettability between the cathode and ILs, preventing the collapse of the graphite structure and enhancing the active material's utilization. The Al//FG full battery assembled with F127 modifying ILs (F127‐0.5) is able to retain a specific capacity of 104.9 mAh g−1 after 1600 cycles, which is higher than ILs (69.0 mAh g−1). This electrolyte interface modification strategy holds considerable practical significance for achieving long‐lifespan and high‐capacity RABs.
Rapid Biofabrication of an Advanced Microphysiological System Mimicking Phenotypical Heterogeneity and Drug Resistance in Glioblastoma
Authors: Pun Sirjana , Prakash Anusha , Demaree Dalee , Krummel Daniel Pomeranz , Sciumè Giuseppe , Sengupta Soma , Barrile Riccardo 
Published: August 2024

AbstractMicrophysiological systems (MPSs) reconstitute tissue interfaces and organ functions, presenting a promising alternative to animal models in drug development. However, traditional materials like polydimethylsiloxane (PDMS) often interfere by absorbing hydrophobic molecules, affecting drug testing accuracy. Additive manufacturing, including 3D bioprinting, offers viable solutions. GlioFlow3D, a novel microfluidic platform combining extrusion bioprinting and stereolithography (SLA) is introduced. GlioFlow3D integrates primary human cells and glioblastoma (GBM) lines in hydrogel‐based microchannels mimicking vasculature, within an SLA resin framework using cost‐effective materials. The study introduces a robust protocol to mitigate SLA resin cytotoxicity. Compared to PDMS, GlioFlow3D demonstrated lower small molecule absorption, which is relevant for accurate testing of small molecules like Temozolomide (TMZ). Computational modeling is used to optimize a pumpless setup simulating interstitial fluid flow dynamics in tissues. Co‐culturing GBM with brain endothelial cells in GlioFlow3D showed enhanced CD133 expression and TMZ resistance near vascular interfaces, highlighting spatial drug resistance mechanisms. This PDMS‐free platform promises advanced drug testing, improving preclinical research and personalized therapy by elucidating complex GBM drug resistance mechanisms influenced by the tissue microenvironment.
Screening and Exploring the Application of the Multifunctional Antioxidant Peptides MSWLC and TSWLC
Authors: Yu Mingtao , Wang Yue , Wang Dayang , Cong Hailin , Yu Bing 
Published: August 2024

AbstractIn this study, an antioxidant pentapeptide library is created based on antioxidant characteristics. The peptides are then purified and separated using liquid chromatography/mass spectrometry (LC/MS) and time‐of‐flight mass spectrometry (TOF). Chemical evaluations identify four peptides with excellent antioxidant activity. The four peptides undergo biocompatibility testing with L‐929, NIH 3T3, and Hep‐G2 cells. A model of hydrogen peroxide‐induced cellular damage in G2 cells shows the peptides' protective and reparative effects against oxidative damage. Two peptides, MSWLC and TSWLC, which perform best overall, are chosen for further analysis. To explore the peptides' potential multifunctionality, acute liver inflammation, keratitis, and aging models are established in mice. MSWLC and TSWLC demonstrate anti‐inflammatory and anti‐aging properties. An antioxidant emulsion prepared by emulsification is found to be non‐irritant in a mouse skin irritation test. In a mouse model exposed to ultraviolet radiation, the sunscreen exhibits excellent UV protection and antioxidant effects. These peptides possess potent antioxidant properties and multifunctionality, indicating broad application potential.
Emergence of Interfacial Magnetism in Strongly‐Correlated Nickelate‐Titanate Superlattices
Authors: Asmara Teguh Citra , Green Robert J. , Suter Andreas , Wei Yuan , Zhang Wenliang , Knez Daniel , Harris Grant , Tseng Yi , Yu Tianlun , Betto Davide , Garcia‐Fernandez Mirian , Agrestini Stefano , Klein Yannick Maximilian , Kumar Neeraj , Galdino Carlos William , Salman Zaher , Prokscha Thomas , Medarde Marisa , Müller Elisabeth , Soh Yona , Brookes Nicholas B. , Zhou Ke‐Jin , Radovic Milan , Schmitt Thorsten 
Published: August 2024

AbstractStrongly‐correlated transition‐metal oxides are widely known for their various exotic phenomena. This is exemplified by rare‐earth nickelates such as LaNiO3, which possess intimate interconnections between their electronic, spin, and lattice degrees of freedom. Their properties can be further enhanced by pairing them in hybrid heterostructures, which can lead to hidden phases and emergent phenomena. An important example is the LaNiO3/LaTiO3 superlattice, where an interlayer electron transfer has been observed from LaTiO3 into LaNiO3 leading to a high‐spin state. However, macroscopic emergence of magnetic order associated with this high‐spin state has so far not been observed. Here, by using muon spin rotation, x‐ray absorption, and resonant inelastic x‐ray scattering, direct evidence of an emergent antiferromagnetic order with high magnon energy and exchange interactions at the LaNiO3/LaTiO3 interface is presented. As the magnetism is purely interfacial, a single LaNiO3/LaTiO3 interface can essentially behave as an atomically thin strongly‐correlated quasi‐2D antiferromagnet, potentially allowing its technological utilization in advanced spintronic devices. Furthermore, its strong quasi‐2D magnetic correlations, orbitally‐polarized planar ligand holes, and layered superlattice design make its electronic, magnetic, and lattice configurations resemble the precursor states of superconducting cuprates and nickelates, but with an S→1 spin state instead.
Ultrasound‐Activated Probiotics Vesicles Coating for Titanium Implant Infections Through Bacterial Cuproptosis‐Like Death and Immunoregulation
Authors: Li Shuoyuan , Yue Yan , Wang Wenqi , Han Mingyue , Wan Xufeng , Li Qiaochu , Chen Xiaoting , Cao Jian , Zhang Yangming , Li Jiyao , Li Jianshu , Cheng Lei , Yang Jiaojiao , Wang Duan , Zhou Zongke 
Published: August 2024

AbstractImplant‐associated infections (IAIs) are the main cause of prosthetic implant failure. Bacterial biofilms prevent antibiotic penetration, and the unique metabolic conditions in hypoxic biofilm microenvironment may limit the efficacy of conventional antibiotic treatment. Escaping survival bacteria may not be continually eradicated, resulting in the recurrence of IAIs. Herein, a sonosensitive metal‐organic framework of Cu‐TCPP (tetrakis(4‐carboxyphenyl) porphyrin) nanosheets and tinidazole doped probiotic‐derived membrane vesicles (OMVs) with high‐penetration sonodynamic therapy (SDT), bacterial metabolic state interference, and bacterial cuproptosis‐like death to eradicate IAIs is proposed. The Cu‐TCPP can convert O2 to toxic 1O2 through SDT in the normoxic conditions, enhancing the hypoxic microenvironment and activating the antibacterial activity of tinidazole. The released Cu(II) under ultrasound can be converted to Cu(I) by exogenous poly(tannic acid) (pTA) and endogenous glutathione. The disruption of the bacterial membrane by SDT can enhance the Cu(I) transporter activity. Transcriptomics indicate that the SDT‐enhanced Cu(I) overload and hypoxia‐activated therapy hinder the tricarboxylic acid cycle (TCA), leading to bacterial cuproptosis‐like death. Moreover, the OMVs‐activated therapy can polarize macrophages to a M2‐like phenotype and facilitate bone repair. The sonodynamic biofilm microenvironment modulation strategy, whereby the hypoxia‐enhanced microenvironment is potentiated to synergize SDT with OMVs‐activated therapy, provides an effective strategy for antibacterial and osteogenesis performance.
Unlocking the Potential of Organic‐Inorganic Hybrid Manganese Halides for Advanced Optoelectronic Applications
Authors: Zhang Wei , Zheng Wei , Li Lingyun , Huang Ping , Xu Jin , Zhang Wen , Shao Zhiqing , Chen Xueyuan 
Published: August 2024

AbstractOrganic‐inorganic hybrid manganese(II) halides (OIMnHs) have garnered tremendous interest across a wide array of research fields owing to their outstanding optical properties, abundant structural diversity, low‐cost solution processibility, and low toxicity, which make them extremely suitable for use as a new class of luminescent materials for various optoelectronic applications. Over the past years, a plethora of OIMnHs with different structural dimensionalities and multifunctionalities such as efficient photoluminescence (PL), radioluminescence, circularly polarized luminescence, and mechanoluminescence have been newly created by judicious screening of the organic cations and inorganic Mn(II) polyhedra. Specifically, through precise molecular and structural engineering, a series of OIMnHs with near‐unity PL quantum yields, high anti‐thermal quenching properties, and excellent stability in harsh conditions have been devised and explored for applications in light‐emitting diodes (LEDs), X‐ray scintillators, multimodal anti‐counterfeiting, and fluorescent sensing. In this review, the latest advancements in the development of OIMnHs as efficient light‐emitting materials are summarized, which covers from their fundamental physicochemical properties to advanced optoelectronic applications, with an emphasis on the structural and functionality design especially for LEDs and X‐ray detection and imaging. Current challenges and future efforts to unlock the potentials of these promising materials are also envisioned.
Supramolecular Assembly of Cesium Copper Iodine Resulting in Rich Emission Properties
Authors: Jiang Meifeng , Lu Xinle , Chen Maosheng , Tong Wenyi , Lin Hechun , Luo Chunhua , Peng Hui , Duan Chungang 
Published: August 2024

AbstractCrown ether‐assisted supramolecular assembly is a robust strategy for manipulating low‐dimensional metal halides. In this study, the supramolecular assembly of 0D‐Cs3Cu2I5 is presented. Upon the addition of 15‐crown‐5 (15C5) to Cs3Cu2I5, 15C5 immediately coordinates with Cs+ to form the cone‐shaped [(15C5)Cs]+. Simultaneously, one of the iodine atoms is removed from the [Cu2I5]3‐ cluster, resulting in the formation of a sub‐planar rhombic [Cu2I4]2− unit. This process leads to white emission, specifically [(15C5)Cs]2[Cu2I4], which exhibits a photoluminescence quantum yield (PLQY) close to unity. The [(15C5)Cs]+ further reacts with 15C5 to form the sandwich‐type cationic structure [(15C5)2Cs]+, accompanied by the generation of red emission [(15C5)2Cs]2[Cu2I4]. By carefully controlling the amount of 15C5, various emission composites can be achieved, particularly tunable white emission. The assembly process is reversible. The pristine Cs3Cu2I5 can be recovered after thermal curing because of the volatility of crown ether and the weak Cs‐crown ether bond. Theoretical calculations have demonstrated that the coordination of the crown ether primarily affects the energy level, leading to changes in the excited state and photophysical properties. The applications in anticounterfeiting and LED phosphors have been demonstrated. This work provides a new approach for the development of low‐dimensional copper halides with promising applications in optoelectronics.
Silicon‐On‐Silicon Carbide Platform for Integrated Photonics
Authors: DeVault Clayton T. , Deckoff‐Jones Skylar , Liu Yuzi , Hammock Ian N. , Sullivan Sean E. , Dibos Alan , Sorce Peter , Orcutt Jason , Awschalom David D. , Heremans F. Joseph , Falk Abram , High Alexander A. 
Published: August 2024

AbstractSilicon carbide (SiC)'s nonlinear optical properties and applications to quantum information have recently brought attention to its potential as an integrated photonics platform. However, despite its many excellent material properties, such as large thermal conductivity, wide transparency window, and strong optical nonlinearities, it is generally a difficult material for microfabrication. Here, it is shown that directly bonded silicon‐on‐silicon carbide can be a high‐performing hybrid photonics platform that does not require the need to form SiC membranes or directly pattern in SiC. The optimized bonding method yields defect‐free, uniform films with minimal oxide at the silicon–silicon–carbide interface. Ring resonators are patterned into the silicon layer with standard, complimentary metal–oxide–semiconductor (CMOS) compatible (Si) fabrication and measure room‐temperature, near‐infrared quality factors exceeding 105. The corresponding propagation loss is 5.7 dB cm−1. The process offers a wafer‐scalable pathway to the integration of SiC photonics into CMOS devices.
Long‐Infrared Broadband Polarization‐Sensitive Absorber with Metasurface Based on Ladder Network
Authors: Yu Haihong , Liang Zhongzhu , Shi Xiaoyan , Yang Fuming , Xu Haiyang , Wu Zhe , Dai Rui , Smith David R. , Liu Yichun 
Published: August 2024

AbstractPlasmonic resonant and metamaterial structures allow for manipulating the polarization properties of electromagnetic waves to achieve polarization beam splitting. Broadband polarization‐sensitive metamaterial absorbers based on surface plasmon polaritons have the advantages of high‐energy utilization and excellent stability, which may replace traditional polarizing devices. Here, an absorber based on a ladder network construction is designed theoretically and investigated experimentally. The absorber can possess almost 92% average absorptivity for TM polarization light in 8–12 µm range (experimental result: 83% from 7 to 11 µm). It is especially sensitive to the polarization angle of incident light, and with the increase of polarization angle, the broadband absorption response can present analogously monotonous reduction. The theoretical and experimental results for TE polarization light are 12% and 25%, respectively. The broadband absorption response performs angle insensitive property under oblique incidence. The proposed metamaterial absorber opens a path to realize broadband polarization‐sensitive absorption based on simple nanostructure. It will possess great potential applications in high‐performance polarimetric photodetectors and imaging fields.
Complementary Cost‐Effective Electrochemical Platforms for Point‐Of‐Use Biosensing
Authors: Monaco Mason , Zamani Marjon , Sarram Ava , Kuo Chao‐Chi , Abeyrathne Chathurika , Li Miaosi , Furst Ariel L. 
Published: August 2024

AbstractThe COVID‐19 pandemic has illustrated the urgent need for rapid and affordable point‐of‐use diagnostics. Electrochemical biosensors are useful for such applications because they enable quantitative readout and show drastically improved sensitivity compared to prevalent lateral flow technologies. However, to‐date, the poor quality of commercially‐available, mass‐produced electrodes has prohibited the scaled production and commercialization of such biosensors beyond glucose sensing. Low‐cost gold leaf electrodes have previously been developed that can be fabricated with no specialized equipment at the point‐of‐use. These electrodes are more effective for biosensing than prevalent commercially‐available systems. Yet, their manual fabrication can be tedious and is not scalable in its current form. Here, performance of mass‐produced gold electrodes generated using roll‐to‐roll manufacturing is evaluated, offering the potential to scale production. Upon comparison of these electrodes with the gold leaf, it is found that these electrodes are high quality, equivalent to the gold leaf electrodes, and support biosensing applications through the detection of both DNase I and BtsI‐v2 activity with comparable performance. These results demonstrate the role of complementary technologies to achieve point‐of‐use sensing by enabling flexibility between mass‐produced manufacture and on‐site production.
Hydrochar Utilization for Saline‐Alkali Soil Amelioration and Its Carbon Sequestration Potential Assessment
Authors: Shen Jia , Jiang Zili , Tang Zhichao , Guo Fanke , Shao Hongyun , Ruan Xiuxiu 
Published: August 2024

AbstractFor the current situation of saline‐alkali soil amelioration, it is urgent to explore a multi‐objective amelioration strategy involving crop income increase and environmental benefits. This study used pine‐needle hydrochar to ameliorate saline‐alkali soil and conducted column and pot experiments to investigate its effects on soil properties and crop growth. And the environmental advantages of hydrochar are evaluated through Life Cycle Assessment (LCA). The electrical conductivity, exchangeable sodium percentage, and pH of saline‐alkali soil ameliorated with hydrochar using the column elution method are reduced by 60%, 58%, and 1.2 pH units, respectively, compared to the original soil. Also, the gene copy number of the ameliorated soil has doubled according to qPCR determination. Pot experiment results show that the root length, fresh weight, and germination rate of wheatgrass are increased by 107, 75, and 20%, respectively. These results demonstrated that the exchange of Na+ with H+ released from hydrochar reduced the soil alkalinity and the viability of organisms is enhanced. Moreover, based on this study's data including the hydrochar dosage and wheatgrass yield, the LCA results showed 3.7 × 109 t CO2e carbon sequestration potential and significant environmental benefits.
Crystal Composition Transformer: Self‐Learning Neural Language Model for Generative and Tinkering Design of Materials
Authors: Wei Lai , Li Qinyang , Song Yuqi , Stefanov Stanislav , Dong Rongzhi , Fu Nihang , Siriwardane Edirisuriya M. D. , Chen Fanglin , Hu Jianjun 
Published: August 2024

AbstractSelf‐supervised neural language models have recently achieved unprecedented success from natural language processing to learning the languages of biological sequences and organic molecules. These models have demonstrated superior performance in the generation, structure classification, and functional predictions for proteins and molecules with learned representations. However, most of the masking‐based pre‐trained language models are not designed for generative design, and their black‐box nature makes it difficult to interpret their design logic. Here a Blank‐filling Language Model for Materials (BLMM) Crystal Transformer is proposed, a neural network‐based probabilistic generative model for generative and tinkering design of inorganic materials. The model is built on the blank‐filling language model for text generation and has demonstrated unique advantages in learning the “materials grammars” together with high‐quality generation, interpretability, and data efficiency. It can generate chemically valid materials compositions with as high as 89.7% charge neutrality and 84.8% balanced electronegativity, which are more than four and eight times higher compared to a pseudo‐random sampling baseline. The probabilistic generation process of BLMM allows it to recommend materials tinkering operations based on learned materials chemistry, which makes it useful for materials doping. The model is applied to discover a set of new materials as validated using the Density Functional Theory (DFT) calculations. This work thus brings the unsupervised transformer language models based generative artificial intelligence to inorganic materials. A user‐friendly web app for tinkering materials design has been developed and can be accessed freely atwww.materialsatlas.org/blmtinker.
Nanomaterials that Aid in the Diagnosis and Treatment of Alzheimer's Disease, Resolving Blood–Brain Barrier Crossing Ability
Authors: Song Qingting , Li Junyou , Li Ting , Li Hung‐Wing 
Published: August 2024

AbstractAs a form of dementia, Alzheimer's disease (AD) suffers from no efficacious cure, yet AD treatment is still imperative, as it ameliorates the symptoms or prevents it from deteriorating or maintains the current status to the longest extent. The human brain is the most sensitive and complex organ in the body, which is protected by the blood–brain barrier (BBB). This yet induces the difficulty in curing AD as the drugs or nanomaterials that are much inhibited from reaching the lesion site. Thus, BBB crossing capability of drug delivery system remains a significant challenge in the development of neurological therapeutics. Fortunately, nano‐enabled delivery systems possess promising potential to achieve multifunctional diagnostics/therapeutics against various targets of AD owing to their intriguing advantages of nanocarriers, including easy multifunctionalization on surfaces, high surface‐to‐volume ratio with large payloads, and potential ability to cross the BBB, making them capable of conquering the limitations of conventional drug candidates. This review, which focuses on the BBB crossing ability of the multifunctional nanomaterials in AD diagnosis and treatment, will provide an insightful vision that is conducive to the development of AD‐related nanomaterials.