bluuebunny/crossref_metadata_2025_split huggingface dataset:
Kunnskapsoppsummering og klassifisering av tiltaket: Grønne tanker - glade barn (2. utg.)
Authors: Eng Helene , Ulvund Stein Erik 
Published: August 2024

Bakgrunn: Denne artikkelen er en kunnskapsoppsummering for effektene av tiltaket Grønne tanker- glade barn. Artikkelen er en revisjon av en tidligere beskrivelse av samme tiltaket i Ungsinn (Eng & Ulvund, 2015), men videreutviklet i henhold til Ungsinn sine nye prosedyrer og kriterier. Grønne tanker – glade barn er en materiellpakke som kan brukes i barnehagen for å stimulere barns tanke- og følelsesbevissthet. Det skal hjelpe barna med å forstå egne og andres følelsesreaksjoner, å bli bedre i stand til å regulere egne følelser og gjennom dette også bidra til et godt psykososialt miljø. Tiltaket kan brukes universelt med mål om å styrke psykosial utvikling for alle barn. Samtidig legges det opp til at en kan bruke materiellet i en styrket innsats for barn som har større utfordringer enn andre med engstelse, sinne eller tristhet. Organisasjonen Voksne for Barn er ansvarlig for implementering av tiltaket i Norge, og de tilbyr også opplæring. Formålet med denne artikkelen er å undersøke om Grønne tanker – glade barn kan antas å være virksomt benyttet i vanlig praksis i Norge.
Metode: Denne kunnskapsoppsummeringen bygger på et systematisk litteratursøk i databasene Embase, Medline og Psykinfo, NORART Cochrane, Cristin, NORA, SCOPUS og SweMed samt informasjon gitt fra tiltakseier i Norge.
Resultater: Resultatene omfatter en oppsummering av tiltakets beskrivelse, foreliggende effektstudier, forskningsmetodisk kvalitet og implementeringskvalitet. Tiltakets bakgrunn, innhold og metoder er godt beskrevet i tiltakets materiell og gjennom to fagartikler. Tiltaket har også god teoretisk og empirisk forankring gjennom kognitiv atferdsterapi, men det foreligger ingen studier der tiltakets effekt er undersøkt. Tiltaket er fritt tilgjengelig, og utover en kort opplæring tilbys det lite implementeringsstøtte. Det finnes heller ikke systemer som sikrer at tiltaket implementeres med god kvalitet. Det er grunn til å tro at tiltaket utøves svært ulikt i forskjellige barnehager, noe som sannsynligvis har betydning for effektene av tiltaket.
Konklusjon: Grønne tanker – glade barn er et tilfredsstillende beskrevet tiltak som åpenbart treffer et behov i folkehelsearbeidet, og som er tilpasset barnehagenes rammeplan. Studier på tiltakets effekter og hvordan tiltaket best utøves for å oppnå eventuelle effekter, er nødvendig for å vite om tiltaket er virksomt. Gjennomføring av en god effektstudie vil imidlertid forutsette en bedre presisering av tiltakets konkrete målsetninger. En god teoretisk forankring styrker sannsynligheten for at tiltaket kan fremme god psykisk helse og redusere vansker for barn i tidlig alder.
Grønne tanker – glade barn klassifiseres på evidensnivå 2 – Teoretisk begrunnede tiltak.
Influence of Auxin on Flowering, Fruit Set and Yield Performance of Yard Long Bean (Vigna unguiculata var. sesquipedalis)
Authors: Nahid Ridwana Afrin , Das Banalata , Parvez Md. Nahid , Akter Thamina , Uddain Jasim 
Published: August 2024

The field experiment was conducted at the Horticultural Farm, Sher-e-Bangla Agricultural University, Dhaka, Bangladesh, to study the effects of different levels of nutrient management and the growth regulator Auxin on the growth and yield of yard-long bean. The experiment was laid out in a randomized complete block design (RCBD) consisted with two factors. Factor A: four levels of nutrient management; i) N0: control (N0, P0, K0) Kg/ha; ii) N1: (N12 P18 K22) Kg/ha; iii) N2: (N18 P27 K33) Kg/ha; iv) N3: (N24 P36 K44) Kg/ha. Factor B: three levels of auxin (indole acetic acid); i) I0: control (0 ppm); ii) I1: 20 ppm; iii) I2: 40 ppm. The variety of yard long bean was BARI borboti-1. The All treatments were replicated three times. The results revealed that nutrient management and auxin significantly affected the plant height, number of leaves, number of branches, number of flowers, number of pods per plant, and pod yield per hectare. In the case of nutrient management, the maximum yield (14.5 t/ha) was observed in the N2 treatment, and the minimum yield (9.61 t/ha) was observed in the N0 treatment. For auxin, the highest yield (12.57 t/ha) was observed from the I2 treatment, and the minimum yield (9.83 t/ha) was observed from the control treatment I0. For the combined effect, the N2I2 treatment combination gave the maximum yield (16.64 t/ha), and the lowest yield (6.37 t/ha) was obtained from the N0I0 combination treatment. So, from the result, it may be concluded that applying 18 kg N/ha, 27 kg P/ha, and 33 kg K/ha with 40 ppm auxin is the best for growth and a higher yield of Yard Long Bean.
Competence as a Moderating Influence of Remuneration and Training on Employee Performance: Study at the Poltekkes Kemenkes Malang, Indonesia
Authors: Prasetyo Andry , Orbaningsih Dwi , Wijayanti Tri Cicik 
Published: August 2024

Employee performance problems in higher education can be influenced by several factors such as lack of motivation caused by inappropriate remuneration practices, competency mismatch, and lack of development opportunities. This study aims to find empirical evidence for the concept of competence as a moderator, providing insight for organizational leaders in designing more effective remuneration and human resource development strategies to achieve good performance for employees. This research method is quantitative, the sample in this study was 100 respondents who met the criteria, with a total population of 621 education personnel at Polkesma. Data analysis was carried out using the Partial Least Square (PLS) method using SmartPLS software version 3. Hypothesis testing uses the statistical value then for alpha 5% by comparing t count with t table. The results showed that there was an influence between remuneration on employee performance with at statistics value of 3.076, there was an influence between training on employee performance with at statistics value of 3.981. Then in the third hypothesis shows there is an effect of remuneration on employee performance which is strengthened by competence with a t statistics value of 2.715. And there is no significant effect on training on employee performance which is weakened by competence with at statistics value of 1.645. This study contributes significantly to the field of human resource management by demonstrating the critical role of remuneration and training in enhancing employee performance. The findings underscore the necessity for organizations to invest in appropriate remuneration strategies and effective training programs to optimize employee output. Additionally, the moderating role of competence provides valuable insights into how individual capabilities can influence the efficacy of these interventions, offering a nuanced understanding of performance improvement mechanisms in educational institutions.
Impact of quality control of satellite soil moisture data on their assimilation into land surface model
Authors: Yin Jifu , Zhan Xiwu , Zheng Youfei , Liu Jicheng , Hain Christopher R. , Fang Li 
Published: July 2014

AbstractA global Soil Moisture Operational Product System (SMOPS) has been developed to process satellite soil moisture observational data at the NOAA National Environmental Satellite, Data, and Information Service for improving numerical weather prediction (NWP) models at the NOAA National Weather Service (NWS). A few studies have shown the benefits of assimilating satellite soil moisture data in land surface models (LSMs), which are the components of most NWP models. In this study, synthetic experiments are conducted to determine how soil moisture data quality control may impact the benefit of their assimilation into LSMs. It is found that using green vegetation fraction to quality control the SMOPS soil moisture product may significantly increase the benefit of assimilating it into Noah LSM in terms of increasing the agreement of Noah LSM surface and root zone soil moisture simulations with the corresponding in situ measurements. The quality control procedures and parameters are suggested for the assimilation of SMOPS data into NWS NWP models.
Zonal momentum budget along the equator in the Indian Ocean from a high‐resolution ocean general circulation model
Authors: Nagura Motoki , McPhaden Michael J. 
Published: July 2014

AbstractThis study examines the zonal momentum budget along the equator in the Indian Ocean in a high‐resolution ocean general circulation model. Wyrtki Jets, wind‐driven eastward flows in the upper 100 m that appear typically twice per year in boreal spring and fall, are a prominent feature of the ocean circulation in this region. Our results indicate that nonlinearity associated with these jets is an important element of the zonal momentum budget, with wind driven eastward momentum advected downward into the thermocline. This advection results in annually averaged zonal currents that flow against the zonal pressure gradient in the upper 200 m, such that there is no mean subsurface undercurrent in the Indian Ocean as there is in the Pacific and Atlantic Oceans. Zonal momentum is further distributed along the equator by zonal advection, with eastward flow substantially enhanced in the eastern basin relative to the western basin. Meridional advection, though generally weak, tends to decelerate surface eastward flow along the equator. These results contrast with those from previous idealized wind‐forced model experiments that primarily emphasized the importance of vertical momentum advection. Also, beyond semiannual period fluctuations, significant momentum advection results from a broad range of interacting processes, spanning intraseasonal to interannual time scales. We conclude that proper simulation of zonal flows along the equator in the Indian Ocean, including their climatically relevant impacts on the mass and heat balance, requires accurate representation of nonlinearities that derive from a broad range of time and space scales.
Modeling intersite dependence for regional frequency analysis of extreme marine events
Authors: Weiss Jérôme , Bernardara Pietro , Benoit Michel 
Published: July 2014

AbstractThe duration of observation at a site of interest is generally too low to reliably estimate marine extremes. Regional frequency analysis (RFA), by exploiting the similarity between sites, can help to reduce uncertainties inherent to local analyses. Extreme observations in a homogeneous region are especially assumed to follow a common regional distribution, up to a local index. The regional pooling method, by gathering observations from different sites into a regional sample, can be employed to estimate the regional distribution. However, such a procedure may be highly affected by intersite dependence in the regional sample. This paper derives a theoretical model of intersite dependence, dedicated to the regional pooling method in a “peaks over threshold” framework. This model expresses the tendency of sites to display a similar behavior during a storm generating extreme observations, by describing both the storm propagation in the region and the storm intensity. The proposed model allows the assessment of (i) the regional effective duration of the regional sample and (ii) different regional hazards, e.g., return periods of storms. An application to the estimation of extreme significant wave heights from the numerical sea‐state database ANEMOC‐2 is provided, where different patterns of regional dependence are highlighted.
Solute transport in aquifers of arbitrary variability: A time‐domain random walk formulation
Authors: Cvetkovic Vladimir , Fiori Aldo , Dagan Gedeon 
Published: July 2014

AbstractSolute transport in three‐dimensional aquifers, with spatially varying hydraulic conductivity of arbitrary point distribution is investigated. The basis of our study is a multiindicator model (MIM) representation of the heterogeneity, combined with a self‐consistent approximation for groundwater flow and particle transport. A time‐domain random walk (TDRW) approach is presented for computing the expected mass arrival along the longitudinal transport direction that is simple and honors the hydrodynamics of flow for any variability. Using hydraulic conductivity measurements at the MADE site and the MIM, it is shown that the travel time distribution for large variability, cannot be well reproduced by the common distributions used for modeling hydrological transport, such as the log‐normal distribution, or the inverse‐Gaussian distribution. The proposed TDRW approach directly relates to the Lagrangian trajectory formulation and is appropriate for applications where occurrence of negative flow velocities is small. These results open new possibilities for modeling solute transport in aquifers of arbitrary variability by the time‐domain random walk that can readily account for a wide range of mass transfer reactions.
Haplotype and nucleotide variation in the exon 3‐VNTR of the DRD4 gene from indigenous and urban populations of Mexico
Authors: Aguirre‐Samudio Ana Julia , Cruz‐Fuentes Carlos Sabás , González‐Sobrino Blanca Zoila , Gutiérrez‐Pérez Verónica , Medrano‐González Luis 
Published: July 2014

ObjectiveTo describe the population structure of the 48‐bp variable number of tandem repeats (VNTR), located in exon 3 of the dopamine receptor D4 gene (DRD4), in 41 Tarahumara from northern Mexico, 20 Mixe from southern Mexico, and 169 people from Mexico City.MethodsGenotypes for the DRD4‐VNTR were determined, from which 15 Tarahumara, eight Mixe, and 37 urban homozygous individuals were sequenced. Repeat‐allele frequencies were compared with other world populations.ResultsThe DRD4‐VNTR variation in Mexico City appeared similar to the world mean. For the Mixe and Maya, DRD4‐VNTR diversity appeared closer to South American groups whereas the Tarahumara were similar to North American groups. People from Mexico City and the Mixe exhibited attributes of a large and admixed population and an isolated population, respectively. The Tarahumara showed endogamy associated with a substructure as suggested by a preliminary regional differentiation. For the DRD4‐VNTR and/or the adjacent 5′‐173 bp sequence, the three populations exhibited negative Tajima's D. Two new VNTR haplotypes were discovered: one in Mexico City and another among the Tarahumara.ConclusionsA differentiation in the DRD4‐VNTR of global relevance occurs between northern and southern populations of Mexico suggesting that the Mexican Trans‐volcanic Belt has been a major frontier for human dispersion in the Americas. Ancient trespass of this barrier appears thus related to a major change in the population structure of the DRD4‐VNTR. Distinctive and independent patterns of DRD4‐VNTR diversity occur among the two Mexican indigenous populations by a still undefined combination of drift and selection. Am. J. Hum. Biol. 26:682–689, 2014. © 2014 Wiley Periodicals, Inc.
Light‐Controlled Chemical Reactions and Their Applications in Biological Systems
Authors: Lee Jeeyeon 
Published: July 2014

AbstractLight has long been used as an external signal to control biological systems. The ability to control chemical reactions with a light stimulus has led to advances in the use of optical techniques for the precise control of biological systems. In particular, light can be used to reversibly control biological processes via photoisomerization of light‐responsive molecules. This Focus Review discusses recent developments of novel light‐controlled compounds including photoresponsive drugs, red light‐shifted azobenzene photoswitches, and synthetic chromophores of fluorescent proteins with new spectroscopic characteristics.
A genetic comparison of two alleged subspecies of Philippine cynomolgus macaques
Authors: Smith David Glenn , Ng Jillian , George Debra , Trask Jessica Satkoski , Houghton Paul , Singh Balbir , Villano Jason , Kanthaswamy Sreetharan 
Published: July 2014

ABSTRACTTwo subspecies of cynomolgus macaques (Macaca fascicularis) are alleged to co‐exist in the Philippines, M. f. philippensis in the north and M. f. fascicularis in the south. However, genetic differences between the cynomolgus macaques in the two regions have never been studied to document the propriety of their subspecies status. We genotyped samples of cynomolgus macaques from Batangas in southwestern Luzon and Zamboanga in southwestern Mindanao for 15 short tandem repeat (STR) loci and sequenced an 835 bp fragment of the mtDNA of these animals. The STR genotypes were compared with those of cynomolgus macaques from southern Sumatra, Singapore, Mauritius and Cambodia, and the mtDNA sequences of both Philippine populations were compared with those of cynomolgus macaques from southern Sumatra, Indonesia and Sarawak, Malaysia. We conducted STRUCTURE and PCA analyses based on the STRs and constructed a median joining network based on the mtDNA sequences. The Philippine population from Batangas exhibited much less genetic diversity and greater genetic divergence from all other populations, including the Philippine population from Zamboanga. Sequences from both Batangas and Zamboanga were most closely related to two different mtDNA haplotypes from Sarawak from which they are apparently derived. Those from Zamboanga were more recently derived than those from Batangas, consistent with their later arrival in the Philippines. However, clustering analyses do not support a sufficient genetic distinction of cynomolgus macaques from Batangas from other regional populations assigned to subspecies M. f. fascicularis to warrant the subspecies distinction M. f. philippensis. Am J Phys Anthropol 155:136–148, 2014. © 2014 Wiley Periodicals, Inc.
Alkene–Tetrazine Ligation for Imaging Cellular DNA
Authors: Rieder Ulrike , Luedtke Nathan W. 
Published: July 2014

Abstract5‐Vinyl‐2′‐deoxyuridine (VdU) is the first reported metabolic probe for cellular DNA synthesis that can be visualized by using an inverse electron demand Diels–Alder reaction with a fluorescent tetrazine. VdU is incorporated by endogenous enzymes into the genomes of replicating cells, where it exhibits reduced genotoxicity compared to 5‐ethynyl‐2′‐deoxyuridine (EdU). The VdU–tetrazine ligation reaction is rapid (k≈0.02 M−1 s−1) and chemically orthogonal to the alkyne–azide “click” reaction of EdU‐modified DNA. Alkene–tetrazine ligation reactions provide the first alternative to azide–alkyne click reactions for the bioorthogonal chemical labeling of nucleic acids in cells and facilitate time‐resolved, multicolor labeling of DNA synthesis.
Genome‐Wide DNA Methylation Study Identifies Significant Epigenomic Changes in Osteoarthritic Cartilage
Authors: Jeffries Matlock A. , Donica Madison , Baker Lyle W. , Stevenson Michael E. , Annan Anand C. , Humphrey Mary Beth , James Judith A. , Sawalha Amr H. 
Published: July 2014

ObjectiveTo perform a genome‐wide DNA methylation study to identify DNA methylation changes in osteoarthritic (OA) cartilage tissue.MethodsThe contribution of differentially methylated genes to OA pathogenesis was assessed by bioinformatic analysis, gene expression analysis, and histopathologic severity correlation. Genome‐wide DNA methylation profiling of >485,000 methylation sites was performed on eroded and intact cartilage from within the same joint of 24 patients undergoing hip arthroplasty for OA. Genes with differentially methylated CpG sites were analyzed to identify overrepresented gene ontologies, pathways, and upstream regulators. The messenger RNA expression of a subset of differentially methylated genes was analyzed by reverse transcription–polymerase chain reaction. Histopathology was graded by modified Mankin score and correlated with DNA methylation.ResultsWe identified 550 differentially methylated sites in OA. Most (69%) were hypomethylated and enriched among gene enhancers. We found differential methylation in genes with prior links to OA, including RUNX1, RUNX2, DLX5, FURIN, HTRA1, FGFR2, NFATC1, SNCAIP, and COL11A2. Among these, RUNX1, HTRA1, FGFR2, and COL11A2 were also differentially expressed. Furthermore, we found differential methylation in approximately one‐third of known OA susceptibility genes. Among differentially methylated genes, upstream regulator analysis showed enrichment of TGFB1 (P = 4.40 × 10−5) and several microRNAs including miR‐128 (P = 4.48 × 10−13), miR‐27a (P = 4.15 × 10−12), and miR‐9 (P = 9.20 × 10−10). Finally, we identified strong correlations between 20 CpG sites and the histologic Mankin score in OA.ConclusionOur data implicate epigenetic dysregulation of a host of genes and pathways in OA, including a number of OA susceptibility genes. Furthermore, we identified correlations between CpG methylation and histologic severity in OA.
Brief Report: A Novel Application of Buccal Micronucleus Cytome Assay in Systemic Lupus Erythematosus: A Case–Control Study
Authors: Al‐Rawi Ziad S. , Gorial Faiq I. , Tawfiq Rana Fawzi , Mohammed Ahmed Khaled , Al‐Naaimi Ahmed S. , Al'aadhmi Mohammed A. , Hayyawi Ali A. 
Published: July 2014

ObjectiveSystemic lupus erythematous (SLE) is a systemic autoimmune disease, and both genetic and environmental factors are implicated in its pathogenesis. The aim of this study was to assess cellular and nuclear morphology of SLE using a buccal micronucleus cytome assay.MethodsThis study included 58 SLE patients and 58 healthy age‐ and sex‐matched controls. Patients' baseline characteristics were recorded, and a buccal micronucleus cytome assay was used to measure cellular and nuclear abnormalities in both groups.ResultsSignificantly higher frequencies of micronuclei, nuclear buds, binucleated cells, basal cells, condensed chromatin cells, karyorrhectic cells, pyknotic cells, and karyolytic cells were seen in SLE patients as compared to controls. A buccal micronucleus cytome assay score of ≥4 had the highest accuracy (93.1%), almost perfect positive predictive value (98.1% at 50% pretest probability and 99.8% at 90% pretest probability), 87.9% sensitivity, and 98.3% specificity for the diagnosis of SLE.ConclusionBiomarkers of DNA damage, proliferative potential, and cell death were significantly increased in SLE patients. The buccal micronucleus cytome assay was a valid and easy way for clinicians to assess individuals at high risk of developing SLE.
A Protein in the palm of your hand through augmented reality
Authors: Berry Colin , Board Jason 
Published: July 2014

AbstractUnderstanding of proteins and other biological macromolecules must be based on an appreciation of their 3‐dimensional shape and the fine details of their structure. Conveying these details in a clear and stimulating fashion can present challenges using conventional approaches and 2‐dimensional monitors and projectors. Here we describe a method for the production of 3‐D interactive images of protein structures that can be manipulated in real time through the use of augmented reality software. Users first see a real‐time image of themselves using the computer's camera, then, when they hold up a trigger image, a model of a molecule appears automatically in the video. This model rotates and translates in space in response to movements of the trigger card. The system described has been optimized to allow customization for the display of user‐selected structures to create engaging, educational visualizations to explore 3‐D structures. © 2014 by The International Union of Biochemistry and Molecular Biology, 42(5):446–449, 2014.