bluuebunny/crossref_metadata_2025_split huggingface dataset:
The first determination of Eustrongylides excisus Jägerskiöld, 1909 — larvae (Nematoda: Dioctophymatidae) in the pike-perch Sander lucioperca in Vojvodina (Serbia)
Authors: Bjelić-Čabrilo O. , Novakov N. , Ćirković M. , Kostić D. , Popović E. , Aleksić N. , Lujić J. 
Published: February 2014

Abstract
Twenty-one specimens of pike-perch (Sander lucioperca) were caught in the Danube-Tisa-Danube Canal in the city area of Novi Sad for parasitological examination. The presence of nematodes in the muscles was revealed in three fish. The parasites were identified to belong to the species Eustrongylides excisus, for which the pike-perch is a paratenic host. This finding represents the first determination of the larvae in the pike-perch in Serbia. The pike-perch is infected by ingestion of benthos- or plankton-eating fishes, the second intermediate hosts harbouring the fourth-stage nematode larvae. E. excisus is pathogenic to humans, who may be infected by consuming raw or undercooked fish.
Dialogue on ‘Dialogic Education’: Has Rupert gone over to ‘the Dark Side’?
Authors: Matusov Eugene , Wegerif Rupert 
Published: February 2014

This email dialogue that we record and report here between Eugene Matusov and Rupert Wegerif, exemplifies Internet mediated dialogic education. When Eugene emailed Rupert with his initial (mis)understanding of Rupert's position about dialogic pedagogy Rupert felt really motivated to reply. Rupert was not simply motivated to refute Eugene and assert his correctness, although Rupert is sure such elements enter into every dialogue, but also to explore and to try to resolve the issues ignited by the talk in New Zealand. Through this extended dialogue Rupert's and Eugene's positions become more nuanced and focussed. Rupert brings out his concern with the long-term and collective nature of some dialogues claiming that the – "dialogue of humanity that education serves is bigger than the interests of particular students and particular teachers.…" – and so he argues that it is often reasonable to induct students into the dialogue so far so that they can participate fully. On the other hand, Eugene's view of dialogue seems more focussed on personal responsibility, particular individual desires, interests and positions, individual agency and answering the final ethical "damned questions" without an alibi-in-being. Rupert claims that dialogic education is education FOR dialogue and Eugene claims that dialogic education is education AS dialogue. Both believe in education THROUGH dialogue but education through dialogue is not in itself dialogic education. For Rupert dialogic education can include ‘scaffolding’ for full participation in dialogue as long as dialogue is the aim. For Eugene dialogic education has to be a genuine dialogue and this means that a curriculum goal cannot be specified in advance because learning in a dialogue is always emergent and unpredictable. Our dialogue-disagreement is a relational and discursive experiment to develop a new genre of academic critical dialogue. The dialogue itself called to us and motivated us and flowed through us. This dialogue is much bigger than us. It participates in a dialogue that humanity has been having about education for thousands of years. We hope that it also engages you and calls you to respond.
Defending the Secular from its Secularist Critics Albert Camus, Saint Augustine, and the New Atheism
Authors: Carlson John D. 
Published: February 2014

AbstractThere is an intellectual movement afoot—known commonly as “new atheism”—that has undertaken a concerted effort to hijack the secular. This project involves arming secularists who wish to keep religion out of political deliberation, if not public life altogether. There are several moral and intellectual failings of this approach that emanate from the distorted conception of “the secular” that the new atheists presume. While considerable scholarly discussion in the past decade has been paid to problems of secularity, secularism, and the secular more broadly, this scholarship has largely overlooked the ideas and insights of the Nobel Prize–winning writer and philosopher Albert Camus, the centennial of whose birth was celebrated in 2013. An unbeliever distinctive for his humility, Camus at times formed common cause with religious figures and, at other times, engaged them critically. He exemplifies an oft-forgotten conception of the secular first articulated by the church father Saint Augustine. Interestingly, Camus knew and admired Augustine's work even if he didn't share his faith. What they did share—a common upbringing in North Africa, a deep intellectual preoccupation with the problem of evil, and a concern to distinguish the affairs of this world from all forms of political absolutism or heavenly utopianism—formed the basis for a vision of the secular that is much in need in our own polarizing times.
Cultural Grounding for the Transmission of the "Moon Man" Figure in the Tale of the "Predestined Wife" (ATU 930A)
Authors: Zhang Juwen 
Published: February 2014

AbstractFocusing on the "Moon Man" (or matchmaker) in the tale "Predestined Wife" (ATU 930A) in Chinese examples, this article applies the historic-geographic method in a broad cultural context by exploring how the Moon Man figure in the tale has been transmitted and transformed over the past two millennia and is still alive in oral tradition, and how elements in tales rise and fall because of their relations to the fundamental values in the culture. This author argues that any key element in an "imported" tale must have familiar characteristics enabling it to adapt to the local audience and take root and, in turn, strengthen hidden beliefs and values, and that the transformation or migration of tales is the precursor of cultural integration that continues in our everyday practices.
La empresa 60 de las Empresas Morales de Juan de Borja. Posible origen textual de la imagen del caracol
Authors: Martínez Sobrino Alejandro 
Published: February 2014

ABSTRACT: The author of this essay argues that the source of the image of the snail from Juan de Borja’s 60th impresa of his Empresas Morales is textual, and that it can be traced back to the Picta Poesis by Aneau Barthèlemy. KEYWORDS: Source, Snail, Impresa, Empresas Morales, Juan de Borja, Picta Poesis, Aneau Barthèlemy. RESUMEN: El autor defiende, en el presente artículo, que el origen de la imagen del caracol que aparece en la empresa número 60 de las Empresas Morales de Juan de Borja posee un origen escrito y que puede rastrearse hasta la Picta Poesis de Aneau Barthèlemy. PALABRAS CLAVES: Origen, Caracol, Empresa, Empresas Morales, Juan de Borja, Picta Poesis, Aneau Barthèlemy.
Una aproximación a la cultura visual de la fiesta barroca. Los retratos de presencias virtuales
Authors: López de Munain Gorka 
Published: February 2014

ABSTRACT: In this study I deal briefly with some issues related to the visual culture of the Baroque festival; and more specifically, with those related to the royal portraits that were on display during the festive activities. To this end I place special emphasis on developing the concepts of presence, body and virtuality –as applied to those works or visual objects– from an approach that offers a new theoretical framework, namely, that which involves «image studies» or «visual culture studies» (Bildwissenschaft, Bildanthropologie y visual studies). KEYWORDS: Baroque Festival, Royal Portraits, Presence, Body, Virtuality, Image Studies. RESUMEN: En el presente estudio abordaremos brevemente algunas cuestiones relativas a la cultura visual de la fiesta barroca; y más específicamente, aquellas vinculadas a los retratos reales que se exponían durante los actos festivos. Para ello, pondremos especial énfasis en desarrollar los conceptos de presencia, cuerpo y virtualidad –aplicados a dichas obras u objetos visuales–, desde un marco teórico novedoso como es el determinado por los estudios de la imagen o estudios de cultura visual (Bildwissenschaft, Bildanthropologie y visual studies). PALABRAS CLAVES: fiesta barroca, retratos reales, presencia, cuerpo, virtualidad, estudios de la imagen.
Games that People Played in Early Modern Europa and the Emblem
Authors: Daly Peter M. 
Published: February 2014

ABSTRACT: This study explores the existence and readership of board games in 16th and 17th century Europe of an emblematic nature. Such games may have derived from the conversation games featured in Baldassare Castiglione's The Book of the Courtier (1528), a work which includes a passage on emblems. In the Spanish tradition, the Filosofía cortesana moralizada (1587) of Alonso de Barros is a book of instructions on how to play this highly emblematic courtly board game, the board of which has unfortunately been lost. Some English emblems of the 17th century also include emblems likely based on Castiglione that depict the courtier as both warrior and scholar. Future studies need to clarify the readership and social class of these emblematic books and their print history. KEYWORDS: Emblematic Board Games, Readership, Baldassare Castiglione, The Book of the Courtier, Alonso de Barros, Filosofía cortesana moralizada. RESUMEN: Este estudio explora la existencia y número de lectores de juegos de tablero de índole emblemática en la Europa de los siglos XVI y XVII. Tales juegos pueden haberse derivado de El Cortesano de Baltasar Castiglione (1528), obra que incluye un pasaje sobre los emblemas. En la tradición española, la Filosofía cortesana moralizada (1587) de Alonso de Barros es un manual de instrucciones sobre cómo jugar este juego de tablero cortesano de naturaleza emblemática, cuyo tablero, desafortunadadmente, no se ha conservado. Ciertos emblemas ingleses del siglo XVII incluyen emblemas, inspirados probablemente por Castiglione, que retratan al cortesano como guerrero y hombre de letras. La investigación futura debe aclarar el número y posición social de los lectores de estos libros, y la historia de su publicación. PALABRAS CLAVES: Juegos de tablero emblemáticos, Número de lectores, Baltasar Castiglione, El Cortesano, Alonso de Barros, Filosofía cortesana moralizada.
Cuestiones religiosas en los Emblemata (Amberes, 1565) de Adriano Junio
Authors: Espigares Pinilla Antonio 
Published: February 2014

ABSTRACT: In this study I deal briefly with some issues related to the visual culture of the Baroque festival; and more specifically, with those related to the royal portraits that were on display during the festive activities. To this end I place special emphasis on developing the concepts of presence, body and virtuality –as applied to those works or visual objects– from an approach that offers a new theoretical framework, namely, that which involves «image studies» or «visual culture studies» (Bildwissenschaft, Bildanthropologie y visual studies). KEYWORDS: Baroque Festival, Royal Portraits, Presence, Body, Virtuality, Image Studies. RESUMEN: En el presente estudio abordaremos brevemente algunas cuestiones relativas a la cultura visual de la fiesta barroca; y más específicamente, aquellas vinculadas a los retratos reales que se exponían durante los actos festivos. Para ello, pondremos especial énfasis en desarrollar los conceptos de presencia, cuerpo y virtualidad –aplicados a dichas obras u objetos visuales–, desde un marco teórico novedoso como es el determinado por los estudios de la imagen o estudios de cultura visual (Bildwissenschaft, Bildanthropologie y visual studies).PALABRAS CLAVES: fiesta barroca, retratos reales, presencia, cuerpo, virtualidad, estudios de la imagen.
Evidence for a differential sea level rise between hemispheres over the twentieth century
Authors: Wöppelmann Guy , Marcos Marta , Santamaría‐Gómez Alvaro , Martín‐Míguez Belén , Bouin Marie‐Noëlle , Gravelle Médéric 
Published: February 2014

AbstractTide gauge records are the primary source of sea level information over multidecadal to century timescales. A critical issue in using this type of data to determine global climate‐related contributions to sea level change concerns the vertical motion of the land upon which the gauges are grounded. Here we use observations from the Global Positioning System for the correction of this vertical land motion. As a result, the spatial coherence in the rates of sea level change during the twentieth century is highlighted at the local and the regional scales, ultimately revealing a clearly distinct behavior between the Northern and the Southern Hemispheres with values of 2.0 mm/yr and 1.1 mm/yr, respectively. Our findings challenge the widely accepted value of global sea level rise for the twentieth century.
Meridional maps of Saturn's thermal electrons
Authors: Carbary J. F. , Rymer A. M. 
Published: February 2014

AbstractAll available observations (July 2004 to June 2011) made by the electron spectrometer (ELS) of the Cassini Plasma Science instrument were used to generate meridional maps of thermal electron fluxes (10–20,000 eV) separated by dayside and nightside. The maps had a spatial resolution of 1 × 1 RS (1 RS = 60,238 km), 10° resolution in pitch angle, and full ELS energy resolution. These maps indicate that electron fluxes tend to accumulate along the field lines between the L shells of ~6 and ~13 in apparent association with the flux tube of Rhea. In the vicinity of Rhea's flux tube, the electrons tend to have field‐aligned pitch angle distributions near the equator, especially between ~10 eV and ~500 eV, but can be isotropic or butterfly at different energies north or south of the equator, and there was no strong evidence of field‐aligned electron pitch angle distributions at higher latitudes. The electron fluxes display strong day‐night asymmetries in flux intensity and pitch angle distribution. However, the day‐night asymmetry observed in the ions, seen as a thicker plasma sheet on the dayside, is not observed in the electrons. Finally, the flux distributions approximately resemble those expected from propagation along field lines using conservation of the first adiabatic invariant.
POEMS syndrome: 2014 Update on diagnosis, risk‐stratification, and management
Authors: Dispenzieri Angela 
Published: February 2014

Disease overview: POEMS syndrome is a paraneoplastic syndrome due to an underlying plasma cell neoplasm. The major criteria for the syndrome are polyradiculoneuropathy, clonal plasma cell disorder (PCD), sclerotic bone lesions, elevated vascular endothelial growth factor, and the presence of Castleman disease. Minor features include organomegaly, endocrinopathy, characteristic skin changes, papilledema, extravascular volume overload, and thrombocytosis. Diagnoses are often delayed because the syndrome is rare and can be mistaken for other neurologic disorders, most commonly chronic inflammatory demyelinating polyradiculoneuropathy. POEMS syndrome should be distinguished from the Castleman disease variant of POEMS syndrome, which has no clonal PCD and typically little to no peripheral neuropathy but has several of the minor diagnostic criteria for POEMS syndrome.Diagnosis: The diagnosis of POEMS syndrome is made with three of the major criteria, two of which must include polyradiculoneuropathy and clonal PCD, and at least one of the minor criteria.Risk stratification: Because the pathogenesis of the syndrome is not well understood, risk stratification is limited to clinical phenotype rather than specific molecular markers. The number of clinical criteria is not prognostic, but the extent of the PCD is. Those patients with an iliac crest bone marrow biopsy that does not reveal a plasma cell clone are candidates for local radiation therapy; those with a more extensive or disseminated clone will be candidates for systemic therapy.Risk‐adapted therapy: For those patients with a dominant sclerotic plasmacytoma, first line therapy is irradiation. Patients with diffuse sclerotic lesions or disseminated bone marrow involvement and for those who have progression of their disease 3–6 months after completing radiation therapy should receive systemic therapy. Corticosteroids are temporizing, but alkylators are the mainstay of treatment, either in the form of low dose conventional therapy or high dose with stem cell transplantation. The benefit of anti‐VEGF antibodies is conflicting. Lenalidomide shows promise with manageable toxicity. Thalidomide and bortezomib also have activity, but their benefit needs to be weighed against their risk of exacerbating the peripheral neuropathy. Prompt recognition and institution of both supportive care measures and therapy directed against the plasma cell result in the best outcomes. Am. J. Hematol. 89:214–223, 2014. © 2014 Wiley Periodicals, Inc.
Asymmetrische Hydrierung disubstituierter Furane
Authors: Wysocki Jędrzej , Ortega Nuria , Glorius Frank 
Published: February 2014

AbstractEine enantioselektive Hydrierung disubstituierter Furane in Gegenwart eines chiralen Rutheniumkatalysators mit N‐heterocyclischem Carbenliganden überführt Furane in wertvolle enantiomerenangereicherte, disubstituierte Tetrahydrofurane.
Biosynthesis of Phenylnannolone A, a Multidrug Resistance Reversal Agent from the Halotolerant Myxobacterium Nannocystis pusilla B150
Authors: Bouhired Sarah M. , Crüsemann Max , Almeida Celso , Weber Tilmann , Piel Jörn , Schäberle Till F. , König Gabriele M. 
Published: February 2014

AbstractThe myxobacterial strain Nannocystis pusilla B150 synthesizes the structurally new polyketides phenylnannolone A–C. Apart from some common volatiles and siderophores, these are the first natural products from the genus Nannocystis. Phenylnannolone A shows inhibitory activity towards the ABCB1 gene product P‐glycoprotein and reverses daunorubicin resistance in cancer cells. To decipher the biochemical reactions leading to the formation of phenylnannolone A, the putative biosynthetic genes were identified (phn1, phn2). Phn2 is a polyketide synthase (PKS) with an NRPS‐like loading module, and its domain order is consistent with the phenylnannolone A structure. The functionality and substrate selectivity of the loading module were determined by means of a γ‐18O4‐ATP pyrophosphate exchange and a phosphopantetheine ejection assay. A specific activation of cinnamic acid by the AMP‐ligase was detected. Phn1 is a putative butyryl‐CoA carboxylase (BCC), providing ethylmalonyl‐CoA for the formation of the ethyl‐substituted part of phenylnannolone A. Phn1 is the first BCC found in biosynthetic genes for an ethyl‐substituted natural compound. Biosynthesis of phenylnannolone A, putatively encoded by phn1 and phn2, thus utilizes the first biosynthetic machinery in which both a BCC and a PKS are involved.
Cytochrome P450 as Dimerization Catalyst in Diketopiperazine Alkaloid Biosynthesis
Authors: Saruwatari Takayoshi , Yagishita Fumitoshi , Mino Takashi , Noguchi Hiroshi , Hotta Kinya , Watanabe Kenji 
Published: February 2014

AbstractAs dimeric natural products frequently exhibit useful biological activities, identifying and understanding their mechanisms of dimerization is of great interest. One such compound is (−)‐ditryptophenaline, isolated from Aspergillus flavus, which inhibits substance P receptor for potential analgesic and anti‐inflammatory activity. Through targeted gene knockout in A. flavus and heterologous yeast gene expression, we determined for the first time the gene cluster and pathway for the biosynthesis of a dimeric diketopiperazine alkaloid. We also determined that a single cytochrome P450, DtpC, is responsible not only for pyrroloindole ring formation but also for concurrent dimerization of N‐methylphenylalanyltryptophanyl diketopiperazine monomers into a homodimeric product. Furthermore, DtpC exhibits relaxed substrate specificity, allowing the formation of two new dimeric compounds from a non‐native monomeric precursor, brevianamide F. A radical‐mediated mechanism of dimerization is proposed.
Fabclavines: Bioactive Peptide–Polyketide‐Polyamino Hybrids from Xenorhabdus
Authors: Fuchs Sebastian W. , Grundmann Florian , Kurz Michael , Kaiser Marcel , Bode Helge B. 
Published: February 2014

AbstractThe structure of the fabclavines—unique mixtures of nonribosomally derived peptide–polyketide hybrids connected to an unusual polyamino moiety—has been solved by detailed NMR and MS methods. These compounds have been identified in two different entomopathogenic Xenorhabdus strains, thereby leading also to the identification of the fabclavine biosynthesis gene cluster. Detailed analysis of these clusters and initial mutagenesis experiments allowed the prediction of a biosynthesis pathway in which the polyamino moiety is derived from an unusual type of fatty acid synthase that is normally involved in formation of polyunsaturated fatty acids. As fabclavines show broad‐spectrum activity against bacteria, fungi, and other eukaryotic cells, they might act as “protection factors” against all kinds of food competitors during the complex life cycle of Xenorhabdus, its nematode host, and their insect prey.
Enantioselective Synthesis and Physicochemical Properties of Libraries of 3‐Amino‐ and 3‐Amidofluoropiperidines
Authors: Orliac Aurélie , Routier Julie , Burgat Charvillon Fabienne , Sauer Wolfgang H. B. , Bombrun Agnes , Kulkarni Santosh S. , Gomez Pardo Domingo , Cossy Janine 
Published: February 2014

AbstractThe enantioselective syntheses of 3‐amino‐5‐fluoropiperidines and 3‐amino‐5,5‐difluoropiperidines were developed using the ring enlargement of prolinols to access libraries of 3‐amino‐ and 3‐amidofluoropiperidines. The study of the physicochemical properties revealed that fluorine atom(s) decrease(s) the pKa and modulate(s) the lipophilicity of 3‐aminopiperidines. The relative stereochemistry of the fluorine atoms with the amino groups at C3 on the piperidine core has a small effect on the pKa due to conformationnal modifications induced by fluorine atom(s). In the protonated forms, the CF bond is in an axial position due to a dipole–dipole interaction between the N−H+ and CF bonds. Predictions of the physicochemical properties using common software appeared to be limited to determine correct values of pKa and/or differences of pKa between cis‐ and trans‐3‐amino‐5‐fluoropiperidines.
The High‐Throughput Synthesis and Phase Characterisation of Amphiphiles: A Sweet Case Study
Authors: Feast George C. , Hutt Oliver E. , Mulet Xavier , Conn Charlotte E. , Drummond Calum J. , Savage G. Paul 
Published: February 2014

AbstractA new method for the discovery of amphiphiles by using high‐throughput (HT) methods to synthesise and characterise a library of galactose‐ and glucose‐containing amphiphilic compounds is presented. The copper‐catalysed azide–alkyne cycloaddition (CuAAC) “click” reaction between azide‐tethered simple sugars and alkyne‐substituted hydrophobic tails was employed to synthesise a library of compounds with systematic variations in chain length and unsaturation in a 24‐vial array format. The liquid–crystalline phase behaviour was characterised in a HT manner by using synchrotron small‐angle X‐ray scattering (SSAXS). The observed structural variation with respect to chain parameters, including chain length and degree of unsaturation, is discussed, as well as hydration effects and degree of hydrogen bonding between head groups. The validity of our HT screening approach was verified by resynthesising a short‐chain glucose amphiphile. A separate phase analysis of this compound confirmed the presence of numerous lyotropic liquid–crystalline phases.