bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fingerprinting the Robust Recovery of Antarctic Ozone
Authors: Wang Peidong , Solomon Susan , Santer Benjamin , Kinnison Douglas , Fu Qiang , Stone Kane , Zhang Jun , Manney Gloria , Millan Luis 
Published: August 2024

Abstract

The Antarctic ozone “hole” was discovered in 19851, and its primary cause is man-made ozone-depleting substances (ODS)2. Following reductions of ODSs under the Montreal Protocol3, signs of ozone recovery have been reported, based largely on observations and broad yet compelling model-data comparisons4. While such approaches are highly valuable, they do not establish levels of overall confidence that account for the temporal and spatial structure of Antarctic ozone trends as well as uncertainties in internal climate variability. Here, we rely on trend pattern information as a function of month and height to separate anthropogenically forced ozone responses from internal variability, using pattern-based detection and attribution (D&A) methods as employed in climate change studies5–11. The analysis uses satellite observations together with both single-model and multi-model ensemble simulations to identify and quantify the month-height Antarctic ozone recovery “fingerprint”12. We demonstrate that the data and simulations show remarkable agreement in the fingerprint pattern of the ozone response to decreasing ODS forcing since 2005. We also show that ODS forcing has enhanced ozone internal variability during the austral spring, influencing detection of forced responses and their time of emergence. Our results provide robust statistical and physical evidence that actions taken under the Montreal Protocol to reduce ODSs are indeed resulting in Antarctic ozone recovery.
Experimental Investigation on the Low-velocity Impact of Beetle Elytron-inspired Plates
Authors: Song Yiheng , Yang Haixia , Chen Jinxiang 
Published: August 2024

Abstract

The elytra of beetles feature a naturally evolved sandwich structure that offers a lightweight and protective function, especially effective against falling object impacts in complex environments. Consequently, structures mimicking the design of beetle elytra hold potential applications in fields requiring resistance to low-speed impacts, such as civil automotive and aviation industries. This study investigates the impact resistance of two beetle-inspired sandwich plates, end- trabecular beetle elytron plates (EBEP) and grid beetle elytron plates (GBEP), comparing their performance with widely used honeycomb plates (HP) and grid plates (GP). Utilizing 3D printing technology and environmentally friendly polylactic acid (PLA) as the material, samples of these four types of sandwich plates were integrally fabricated and tested under a 10 J impact energy to assess their impact response, damage mode, and characteristics. The results showed that, compared to HP and GP, the average peak force of EBEP and GBEP increased by 29.38% and 17.06%, respectively. Additionally, GBEP's impact resistance indicators, including specific energy absorption (SEA), were 2.9% to 5.4% higher than those of GP, with maximum peak force (MPF), mean compressive force (Fm), and crush force efficiency (CFE) increasing by 5.0%, 24.5%, and 17.8%, respectively. For EBEP, apart from a slight decrease in CFE (2.6%), SEA was 7.8% to 9.2% higher than HP's, while MPF and Fm increased by 18.2% and 15.2%, respectively. Furthermore, damage analysis revealed that the central residual indentation depth of HP was 640% greater than that of EBEP, and GP's was 63.1% greater than that of EBEP. These experimental results validate that beetle plates have significant advantages in load-bearing capacity and impact resistance.
Identification of defects on the inner wall of water supply pipes based on the optimized residual network
Authors: Zhao Qian , Wang Gaojuan 
Published: August 2024

ABSTRACT
The urban water supply network is part of the infrastructure that sustains the economic and social functions of cities and regions. Timely inspection and maintenance of the network can effectively reduce resource wastage and prevent accidents. Traditional manual detection methods are inefficient and can be based on subjective judgments. A classification model based on an improved ResNet34 network has been proposed to classify and detect various types of corrosion on the inner walls of pipes under challenging conditions. The introduction of the attention mechanism and multi-scale feature fusion modules further improved the model's effectiveness in classifying defects within the inner walls of pipes. The model can detect various types of pipeline corrosion with a detection accuracy of 98.61%. This accuracy is significantly superior to that achieved with traditional models such as ResNet34, AlexNet, MobileNet, and VGGNet.
Balance of water footprint using an input–output economic model in semi-arid regions
Authors: Tarvirdizadeh Elmira , Hosseini Seyed Abbas , Abedi Zahra , Alipour Mohammad Sadegh 
Published: August 2024

ABSTRACT
This research estimates the water footprint and the share of imported and exported virtual water for each economic product in the input–output (IO) economic model of 2001, 2011, and 2016 based on top-down approach in Iran in the Middle East region. The IO model can quantify the virtual water content of agricultural and industrial products, as well as other services involved with the economy. Based on the findings of this study, the national water footprint (NWF) has increased in economic sectors over the studied years, with the highest footprint in the agricultural sector. Iran has been a net importer of virtual water due to importing more products than exports during 2001 and 2016. In addition, the commercial balance of virtual water has increased over these years. The results show that Iran's NWF is increasing rapidly, while the water footprint per capita and biological water capacity are decreasing. This indicates that the country is experiencing significant water stress due to the excessive and uncontrolled withdrawal of water resources, more than the limits of sustainable development. To address this issue, policymakers need to pay special attention to the virtual water trade in terms of integrated water resources management.
Regioselective Thiolation of Indole to Construct 3-Arylthioindoles
Authors: Yadav Ashvani , Kumar Rohit , Yadav Vikas , Ghosh Mitushree , Prasad Virendra 
Published: August 2024

:
A practical and novel approach for the regioselective synthesis of 3-arylthioindole
derivatives has been accomplished using a combination of indole substrates with p-toluene
sulfonyl hydrazide. This methodology employs NIS as the oxidant and PPh3 as the reductant
to give the desired 3-arylthioindoles in good to excellent yields. This method offers several
advantages, including simplicity, operational ease, and broad substrate scope.
Use of Olives-derived Phytochemicals for Prevention and Treatment of Atherosclerosis: An Update
Authors: Dabravolski Siarhei A. , Pleshko Elizaveta M. , Sukhorukov Vasily N. , Glanz Victor Y. , Sobenin Igor A. , Orekhov Alexander N. 
Published: August 2024

:
Mediterranean diet is frequently associated with longevity and a lower incidence of adverse
cardiovascular events because of the biological activities and health effects of olives - its
key component. Olive oil, olive leaf extract, fruits and different by-products contain many bioactive
components that exert anti-oxidant, anti-inflammatory and anti-apoptotic activities. In this review,
we focus on the recent studies exploring molecular mechanisms underlying the cardioprotective
properties of different olive oils, olive leave extracts, and specific micro-constituents (such as
oleuropein, tyrosol, hydroxytyrosol and others) in vitro on rodent models and in clinical trials on
human subjects. Particularly, hydroxytyrosol and oleuropein were identified as the major bioactive
compounds responsible for the antioxidant, anti-inflammatory, anti-platelet aggregation and
anti-atherogenic activities of olive oil. In total, the discussed results demonstrated a positive association
between the consumption of olive oil and improvement in outcomes in atherosclerosis, diabetes,
myocardial infarction, heart failure, hypertension and obesity.
Method Development and Validation for Quantification of Quercetin in Blood Plasma of Wistar Rats Using LC-MS/MS
Authors: Panda Bhisma Narayan , Gupta Sapna , Kumari Premlata , Singh Ruchi , Bhat Binu , Pramod Ravindran Kumar 
Published: August 2024

Background:
Quercetin is a flavanol that has demonstrated pharmaceutical properties
such as anti-inflammatory, antioxidant, and anti-carcinogenic properties. However, parenteral formulations
of quercetin are currently not in widespread use due to its poor aqueous solubility, fast
metabolism, and low bioavailability.

Objective:
This study aimed to develop a quick, simple, and accurate method for the quantification
of quercetin using ultra-fast liquid chromatography-tandem mass spectrometry (LC-MS/MS).

Methods:
A rapid and sensitive LC-MS/MS method was developed and fully validated for the
quantification of quercetin in rat plasma after intravenous administration. Quercetin reference standard
was used for the method development as well as in-vivo validation. ACQUITY UPLC BEH
C18 Column (2.1 x 50 mm, 1.7 μm) was used for the chromatographic separation. The mobile
phase consisted of solution A (water with 0.1% formic acid) and solution B (methanol: acetonitrile
with 0.1% formic acid in the ratio of 1:1) with a flow rate of 0.350 μL/min. Further, the
method was applied to quantify and pharmacokineticly profile quercetin in the blood plasma of
outbred male and female Wistar rats.

Results:
The accuracy of the method was calculated for intraday and inter-day, which came out as
≤ 85.23% and 84.87%, respectively. The precision of the method calculated for intraday was
≤3.02%, and for inter-day was ≤2.75%. The percentage recovery was found to be ≤85.23% for intraday
and ≤84.87% for inter-day. The Relative Standard Deviation was 0.04 for intraday and 1.10
for inter day, respectively.

Conclusion:
The developed method has an advantage over other reported methods because of its
short run time of 6 minutes as well as its short time of data registration of approximately 2.5 minutes.
This method can be used for the routine analysis of quercetin in vivo animal studies.
A Novel Synthesis and Quantitation Route of Belinostat
Authors: Laxmi Kumari Nagarapu , Sudhakar Chithaluri 
Published: August 2024

Introduction:
This research article describes the production, quantification, and purification
of belinostat from 3-nitrobenzaldehyde as the starting material. A cascade-step process produces
higher yields when compared to all previous existing methodologies.

Method:
The procedure involved the following: Horner–Wadsworth–Emmons (HWE) reaction of
aromatic aldehydes with triethylphosphonoacetate in the presence of potassium carbonate, reduction
of the nitro group to the amino group, sulfochlorination by thionyl chloride, aniline-mediated
sulfonamidation, and hydroxylamine amidation as the last step.

Results:
The prepared solid belinostat was purified, and an acceptable yield of 56-60% was obtained.

Conclusion:
The approach has several key benefits, including low-cost beginning materials,
straightforward techniques, safer and more reliable results, and substantial environmental advantages.
In-Home Positioning for Remote Home Health Monitoring in Older Adults: Systematic Review
Authors: Chan Andrew , Cai Joanne , Qian Linna , Coutts Brendan , Phan Steven , Gregson Geoff , Lipsett Michael , Ríos Rincón Adriana M 
Published: August 2024

Background
With the growing proportion of Canadians aged >65 years, smart home and health monitoring technologies may help older adults manage chronic disease and support aging in place. Localization technologies have been used to support the management of frailty and dementia by detecting activities in the home.

Objective
This systematic review aims to summarize the clinical evidence for in-home localization technologies, review the acceptability of monitoring, and summarize the range of technologies being used for in-home localization.

Methods
The PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) methodology was followed. MEDLINE, Embase, CINAHL, and Scopus were searched with 2 reviewers performing screening, extractions, and quality assessments.

Results
A total of 1935 articles were found, with 36 technology-focused articles and 10 articles that reported on patient outcomes being included. From moderate- to high-quality studies, 2 studies reported mixed results on identifying mild cognitive dementia or frailty, while 4 studies reported mixed results on the acceptability of localization technology. Technologies included ambient sensors; Bluetooth- or Wi-Fi–received signal strength; localizer tags using radio frequency identification, ultra-wideband, Zigbee, or GPS; and inertial measurement units with localizer tags.

Conclusions
The clinical utility of localization remains mixed, with in-home sensors not being able to differentiate between older adults with healthy cognition and older adults with mild cognitive impairment. However, frailty was detectable using in-home sensors. Acceptability is moderately positive, particularly with ambient sensors. Localization technologies can achieve room detection accuracies up to 92% and linear accuracies of up to 5-20 cm that may be promising for future clinical applications.

Trial Registration
PROSPERO CRD42022339845; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=339845
WINTER ELSA LAW SCHOOL "WELS Niš" 2024
Authors: Sekulić Lenka , Jovanović Vuksan , Milić Nađa 
Published: August 2024

In this report, we present the results achieved in the Winter ELSA Law School (WELS) Niš, organized in the period from 18 - 25 February 2024 by ELSA Niš. The WELS project aims to allow students from various European countries to acquire new knowledge from different spheres of legal life, make new friendships, and connect with other young lawyers across Europe. The local group ELSA Niš organized this event for the first time in February 2024. In addition to the rich academic program on the topic of “Business Law and IT Law” prepared for the WELS Niš participants, the local group ELSA Niš managed to present the City of Niš and the Serbian culture to our friends from all over Europe. During the five-day event, held on the premises of the Science and Technology Park Niš and the Faculty of Law, University of Niš, our lecturers covered a range of topics which included: the legal framework of information technologies in the European Union, the legal regulation of blockchain technology, strategies for the defense of a joint-stock company against a hostile takeover, the phenomenon of mass tort claims, and many more up-to-date topics in the sphere of Business Law and IT Law. The lecturers who generously participated in the WELS Niš are prominent experts in their fields, including well-known lawyers, businessmen, and professors from the Faculty of Law, University of Niš.
Reconfigurações alegóricas de uma Revolução
Authors: Dias Maria Heloisa Martins 
Published: August 2024

A partir da focalização de um episódio nuclear do romance Paisagem com mulher e mar ao fundo (1982), de Teolinda Gersão, este artigo propõe suscitar reflexões sobre os sentidos desdobrados da figura opressora de Oliveira Salazar e os efeitos de sua ação ditatorial sobre o país. Não apenas o conteúdo político contido nesse momento histórico, mas, principalmente, o modo como esse recorte é tratado ficcionalmente e gera efeitos para além da pontualidade do acontecimento. Nesse caso, o “acontecimento” (noção colocada por Jacques Derrida) tem que ver com a linguagem, enquanto “desconstrução” e “diferença”, enfim, uma escrita enquanto “devir” que rasura o factual para re-configurá-lo em outro espaço – o da escritura. É por meio desta que a romancista portuguesa utiliza alegorias que problematizam, tanto a figura do Poder quanto a da massa revolucionária que busca derrubá-lo. Visionarismo, mitogenia, sacralização, ritos religiosos, profanação, polifonia acabam despontando na narrativa como recursos estéticos que propiciam interessantes indagações sobre a Revolução de Abril. Eis a atualidade desse romance de Teolinda Gersão. Nosso corpus crítico está constituído por Rolando Barthes, Octavio Paz, Walter Benjamin, José Miguel Wisnik, Flávio Kothe, entre outros autores.
Revolução, palavra-mulher: a respeito de alguma poesia de Maria Teresa Horta e Natália Correia
Authors: Fonseca Carlos Henrique 
Published: August 2024

Maria Teresa Horta e Natália Correia são duas autoras de extrema importância na Literatura Portuguesa, fazendo de sua poesia um espaço de compromisso com o seu tempo referencialmente histórico e, recorrentemente, discutindo o papel da mulher. Com base nesse viés, o presente artigo tem por objetivo ser uma revisitação crítica a dois livros das autoras: Mulheres de Abril (1977), de Teresa Horta, e as Cantigas de amigo, publicadas como inéditos na reunião da poesia de Natália Correia, O Sol nas Noites e o Luar nos Dias (1993). Com base na leitura de alguns poemas selecionados, este trabalho pretende discutir como a discursividade poética em feminino das duas autoras tematizou o 25 de Abril.
Clinical and epidemiological aspects Astrakhan rickettsial fever depending on severity of illness
Authors: Бедлинская Н.Р. , Галимзянов Х.М. , Мирекина Е.В. 
Published: August 2024

Сравнительный анализ и комплексное изучение клиникоэпидемиологических проявлений Астраханской риккетсиозной лихорадки (АРЛ) позволили выявить эпидемиологические аспекты и клинические особенности течения заболевания в зависимости от степени тяжести.
A comparative analysis and a comprehensive study of the clinical and epidemiological manifestations of Astrakhan rickettsial fever (ARF) made it possible to identify the epidemiological aspects and clinical features of the course of the disease, depending on the severity.
Population bases for management of small mammals
Authors: Щипанов Н.А. 
Published: August 2024

Дан обзор основных подходов к описанию и моделированию популяционных реакций. Функционирование локальных популяций рассмотрено как альтернативное: контроль и восстановление. С учетом возможности и механизмов изменения функции виды могут быть объединены в три группы с прогнозируемыми ожидаемыми демографическими характеристиками, возможными негативными последствиями контроля, устойчивостью к действию факторов и скоростью восстановления локальной популяции.
An overview of the main approaches to the description and modeling of population process is given. The functioning of local populations is considered as an alternative: control vs. recovery. Taking into account the possibilities and mechanisms for changing the function, species can be combined into three groups with expected demographic patterns, predictable negative consequences of control, with prognoses of resistance to impacts and the rates of recovery of populations.
Emergent zoonoses associated with bats
Authors: Макаров В.В. , Барсуков О.Ю. , Барсуков Ю.И. 
Published: August 2024

Категория эмерджентных инфекций насчитывает более 300 новых, кардинально меняющих стереотипы или возвращающихся (реэмерджентных) особо опасных, социально и экономически значимых нозоединиц животных и человека. Выход возбудителей за рамки сложившихся естественных симбиосистем хозяин патоген среда происходит преимущественно как следствие прямой или синергизирующей разрушительной антропо и техногенной деятельности в планетарном масштабе и провоцирует чрезвычайные проблемы ветеринарной и гуманной медицины. Трафик патогенов в направлении природные резервуары домашние животные, человек сопровождается необычными для ортодоксальной эпидемиологии явлениями, такими как пострезервуарная амплификация инфекции, индексслучаи, внесистемная заболеваемость типа спилловер (spill over). Примерами таких явлений служат эмерджентные вирусные зоонозы с природными резервуарами в популяциях рукокрылых новые для науки и практики болезни Хендра и Нипах, тяжелый острый и ближневосточный респираторные синдромы, марбург и эболавирусные болезни, возникновение которых на рубеже столетий сопровождалось чрезвычайными последствиями для гуманной и ветеринарной медицины, а также лиссавирусные инфекции.
The category of emergent infections includes more than 300 new, radically changing stereotypes or reemergent especially dangerous, socially and economically significant nosoforms of the animal and human. The release of pathogens beyond the established natural host pathogen environment symbiosis occurs primarily as a result of direct or synergistic destructive anthropogenic activities on a global scale and provokes extreme problems of veterinary and humane medicine. Traffic pathogens with vector of natural reservoirs domestic animals, man is accompanied by phenomena that are unusual for orthodox epidemiology, such as postreserve amplification of infection, index cases, and offsystem morbidity of the spill over type. Demonstrative examples of emergent phenomena are viral zoonoses natural reservoirs that serve populations of bats there is new to the science and practice of diseases Hendra and Nipah, Severe Acute and the Middle East Respiratory Syndromes, Marburg and Ebolaviruse diseases the occurrence of which in the turn of the century was accompanied by extraordinary disasters on human and veterinary medicine as well as lyssavirus infections.
Aspects of production and control of microcapsulated insecticide compositions. I. Determination of particle size
Authors: Львовский А.И. , Носикова Л.А. , Кочетов А.Н. 
Published: August 2024

Рассмотрены возможности определения размера частиц в коммерческих и опытной композициях, произведенных с использованием технологии микрокапсулирования инсектицидных субстанций. В качестве капсулообразователей фигурировали различные строительные блоки природные липиды (животного и растительного происхождения) и синтетические полимерные материалы, при этом в качестве инкапсулированных инсектицидных субстанций рассматривались синтетические пиретроидные и фосфорорганические производные. Рассмотрены несколько вариантов проведения оценки размеров частиц в растворах инсектицидных микрокапсулированных средств. Установлено, что для корректного определения размера частиц необходимо проводить разбавление исходных композиций до концентраций ниже установленных значений для рабочих растворов. Диапазон размера частиц, выявленный в процессе исследования, позволяет отнести все рассмотренные композиции к микрокапсулированным.
The possibilities of determining the particle size in commercial and experimental compositions produced using the technology of microencapsulation of insecticidal substances are considered. Various building blocks natural lipids (of animal and plant origin) and synthetic polymeric materialswere used as capsuleformers, while different classes of organic compounds pyrethroid and organophosphorus derivativeswere considered as encapsulated insecticidal substances. The evaluation of particle sizes in the working solutions of microencapsulated insecticidal means. It is established that for the correct determination of the particle size it is necessary to dilute the initial compositions to concentrations below the set values for the working solutions. The range of particle size, revealed in the course of the study, allows us to refer all the considered compositions really to the microcapsulated ones. We believe it is necessary for the registration of new microencapsulated funds to implement not only control their residual effect on different surfaces and, optionally, monitoring of particle size, because their effectiveness and, perhaps, Toxicological characteristics, certainly, will not equally change the size of the capsules, and thus information on the size and fractional composition will serve as an important characteristics of these formulations.