bluuebunny/crossref_metadata_2025_split huggingface dataset:
A rare 3q13.31 microdeletion including GAP43 and LSAMP genes
Authors: Gimelli Stefania , Leoni Massimiliano , Di Rocco Maja , Caridi Gianluca , Porta Simona , Cuoco Cristina , Gimelli Giorgio , Tassano Elisa 
Published: November 2013

Abstract

Background
Interstitial deletions affecting the proximal long arm of chromosome 3 have been rarely reported in the literature. The deleted segments vary in localization and size with different breakpoints making genotype-phenotype correlation very difficult. Until now, a girl with a 1.9-Mb interstitial deletion of 3q13.2q13.31 and 14 novel patients with deletions in 3q11q23 have been reported.

Results
Here we report on a 7-year-old girl with neuropsychiatric disorders and renal, vascular and skeletal anomalies. Array-CGH analysis revealed a small rare inherited 3q13.31 deletion containing only two genes, GAP43 and LSAMP. The mutation analysis of the two genes was negative on the other non-deleted chromosome. GAP43 is considered a crucial component for an effective regenerative response in the nervous system and its mRNA is localized exclusively to nerve tissue where the protein is linked to the synaptosomal membrane. LSAMP is a 64- to 68-kD neuronal surface glycoprotein found in cortical and subcortical regions of the limbic system that acts as an adhesion molecule and guides the development of specific patterns of neuronal connection. The deleted region is adjacent to a “desert gene” region extending 2.099 Mb.

Conclusions
We discuss the effects of GAP43 and LSAMP haploinsufficiency, proposing that their deletion may be responsible for the main phenotype. Further cases with similar microdeletion are expected to be diagnosed and will help to better characterize the clinical spectrum of phenotypes associated with 3q13.31 microdeletion.
Genetic structure of Bufo bankorensis distinguished by amplified restriction fragment length polymorphism of cytochrome b
Authors: Chen Chu-Chih , Li Kou-Wei , Yu Teng-Lang , Chen Li-Hsuen , Sheu Pei-Yuan , Tong Yi-Wen , Huang Kao-Jean , Weng Ching-Feng 
Published: November 2013

Abstract

Background

Bufo bankorensis is an endemic species in Taiwan, and its populations are geographically and reproductively isolated. However, the distinction of Taiwanese B. bankorensis as a separate species from the Chinese Bufo gargarizans remains in dispute.

Results
A primer set was designed to explore the mitochondrial (mt)DNA cytochrome (Cyt) b sequence (700 bp) of B. bankorensis in 148 individuals collected from 12 locations in Taiwan. After a polymerase chain reaction and sequencing, we found that the nucleotide sequence of Cyt b contained two restricted enzyme sites of Bam HI and Tsp RI. Following Bam HI enzyme digestion, samples of B. bankorensis were divided into two clades: western (which were undigested) and eastern (which were digested) clades. Additionally, Cyt b of the western clade of B. bankorensis was not cut by Bam HI, while it was cut by Tsp RI into two sublineages. The result infers that at least two broadly divergent phylogroups of B. bankorensis exist in Taiwan and are not morphologically distinguishable. Based on the divergent sequence of Cyt b and cutting restriction enzymes, these populations were classified into three distinct phylogroups.

Conclusion
Genetically, one (western group 1, uncut by Bam HI and cut by Tsp RI) is most likely B. gargarizans, a second one (western group 2, uncut by both Bam HI and Tsp RI) is B. bankorensis, and a third one (eastern clade, cut by Bam HI but not cut by Tsp RI) could be a new subspecies. All three phylogroups were found in some areas, suggesting that they are sympatric, not allopatric.
Feeding and Bone Turnover in Gastric Bypass
Authors: Valderas Juan P. , Padilla Oslando , Solari Sandra , Escalona Manuel , González Gilberto 
Published: November 2013

Context:
Roux-en-Y gastric bypass (RYGB) is associated with high bone turnover. In healthy subjects, feeding causes acute reduction of bone resorption, which is regulated by several intestinal and pancreatic peptides.

Objective:
Our objective was to assess bone turnover after feeding in patients with RYGB.

Design and Setting:
This was a cross-sectional case-control study at a university hospital.

Participants:
Fifteen postmenopausal women who underwent RYGB 7.4 ± 4.1 years previously were matched by age and body mass index with 15 nonoperated women (controls).

Main Outcomes:
Serum PTH, calcium, phosphorus, insulin, carboxy telopeptide (CTX), procollagen type I N-terminal propeptide (P1NP), and glucagon-like peptide 2 (GLP-2) were measured while fasting and after a standard meal (SM).

Results:
The fasting calcium, phosphorus, and PTH were similar in both groups and exhibited similar decreases after an SM. The fasting CTX level was higher in the RYGB than in the control group (0.589 ± 0.18 vs 0.382 ± 0.11 ng/mL; P &lt; .05) and fell to a nadir of 42.2% of the basal value in the RYGB and 53.9% in controls (P &lt; .05). The fasting and postprandial P1NP levels were similar in both groups and fell to a nadir of 85.8% in the RYGB and 89.3% in controls. Insulin and GLP-2 levels were similar during fasting in both groups. RYGB patients had exaggerated postprandial insulin and GLP-2 response compared with the controls with the insulin and GLP-2 area under the curve being significantly higher in the RYGB group. There was a significant negative correlation between the peak of insulin levels and the CTX changes.

Conclusion:
The acute reduction in bone resorption after feeding is preserved in RYGB and is even higher than in nonoperated subjects. This phenomenon is related to the increase of postprandial levels of insulin. These findings suggest a bone-protecting mechanism in RYGB that may counteract the elevated bone resorption that occurs during fasting.
Novel Detection Technique for Particulate Matter in Air Using Metal Mesh Device Sensors
Authors: Seto Hirokazu , Kamba Seiji , Kondo Takashi , Ogawa Yuichi , Hoshino Yu , Miura Yoshiko 
Published: November 2013

Abstract
A novel technique for detection of particulate matter in air using metal mesh devices is proposed. A metal mesh device with square apertures was used as membrane filter and as band-pass filter. Frequency shifts in transmittance spectra of the metal mesh device collected with particulate matter had a linear relationship to the particulate matter concentrations with a high coefficient of determination. When metal mesh devices with different opening lengths were stacked, particulate matter was fractionalized by size.
Severe bilateral amyotrophic neuralgia associated with major dysphagia secondary to acute hepatitis E
Authors: Moisset Xavier , Vitello Nicolas , Bicilli Elodie , Courtin Romain , Ferrier Anna , Taithe Frederic , Lahaye Clément , Hssain Ali Ait , Garrouste Cyril , Pierre Clavelou 
Published: November 2013

Introduction:Several acute neurological syndromes can be triggered by immune events. Hepatitis E virus (HEV), an emerging infectious disease, can be one of these triggers.Case report:We report the case of a 36-year-old man that presented nausea and a dull abdominal pain for a week and then felt an acute neuralgic pain involving both shoulders that lasted for 8 to 10 hours. Immediately after, the patient presented a severe bilateral muscular weakness of the proximal part of both upper limbs, corresponding to an amyotrophic neuralgia. Two days after the shoulder pain, the patient presented a dysphagia necessitating tube feeding. A blood sample confirmed hepatitis caused by hepatitis E virus (HEV; genotype 3F). Oral feeding resumed progressively after five months. The patient was fully independent for the activities of daily living but was still unable to work after six months.Conclusion:Amyotrophic neuralgia and hepatitis E are both under-diagnosed. It is noteworthy that HEV can trigger amyotrophic neuralgia. Antiviral drugs, oral steroids and intravenous immunoglobulins can be proposed, but the optimal treatment has not yet been determined.
An identification problem for a semilinear evolution delay equation
Authors: Lorenzi Alfredo , Vrabie Ioan I. 
Published: November 2013

Abstract.
We prove the existence, uniqueness and continuous dependence on the data of a mild
solution to an identification problem for a first-order semilinear delay differential equation in a Banach
space subjected to an overdetermination expressed by means of an integral with respect to an absolutely
continuous measure (with respect to the Lebesgue measure). Two applications to some identification
problems, the first one for a parabolic delay equation and the second one for a hyperbolic delay equation,
are also considered.
Nonlinear Load-Displacement Behavior Observed During Fracture Toughness Testing of Aluminum-Beryllium Material
Authors: McKeighan Peter C. , Donald J. Keith , Svilar Mark 
Published: November 2013

AbstractIn fracture toughness testing on beryllium and aluminum-beryllium materials, the load-displacement response exhibits a significant amount of nonlinearity that requires special, nontraditional methods for analysis. This work is directed toward determining what causes this nonlinearity, focusing on plasticity and subcritical crack extension. Plasticity was indirectly assessed by varying the size of the fracture toughness specimen, whereas crack advance was monitored with unloading compliance during the fracture toughness tests. Neither of these influences appears to be the primary contributor to the nonlinearity. Rather, the range of loading employed during precracking influences the load-displacement response of the material. The central, more linear portion of the load-displacement response appears bounded at the low end by the crack opening load and at the high end by the maximum load applied during the terminal stage of precracking. This region of the load-displacement curve represents an alternative to the standard 20 % to 80 % maximum load analysis region. Although using this region for analysis offers the advantage of representing the portion of the curve where the crack is fully open and behaving in an elastic manner, it will likely increase the number of invalid tests as a result of violation of the Pmax/PQ &lt; 1.1 criterion.
A look at the rokorona language
Authors: Birchall Joshua 
Published: November 2013

AbstractThis paper presents an analysis of the only remaining documentation of the Rokorona language, a collection of three prayers published in Teza (1868). First, a survey of the various mentions of Rokorona in the ethno-historical literature is presented, allowing for new insights into the original homeland of these people. Then, a number of phonological and grammatical features of the language are identified based on the texts. These features show that Rokorona displays a number of grammatical properties typical of Chapacuran languages, and when combined with the available lexical data, allow for the language to be definitively classified as such.
Evaluating historical data (wordlists) in the case of bolivian extinct languages
Authors: Danielsen Swintha 
Published: November 2013

AbstractThis article advocates the reanalysis of historical data on extinct languages in the view of our current knowledge on the grammatical characteristics of possibly related languages.The example given here is a corpus of eight Arawakan languages of Bolivia, of which four are already extinct (Apolista, Joaquiniano, Paikoneka, Saraveka). Even though there are only wordlists available for these extinct languages, it is possible to analyze the data in the light of Arawakan grammar.Those aspects that can be excerpted from all data are taken as typological features in a questionnaire used for phylogenetic analyses. The graphs that result from the feature analysis deliver evidence for certain relations between the languages and those that are still spoken today, which again gives us some idea about the migration of the Arawakan languages, in general.
The nootka and sandwich vocabularies in the relación de la entrada de san lorenzo de nutka (1789)
Authors: Fernández Rodríguez Rebeca 
Published: November 2013

AbstractNootka is an historical fur-trading centre in Yuquot, on the west coast of Vancouver Island, British Columbia, Canada. In 1788, the Spanish king Charles III sent an expedition to Nootka commanded by Ignacio Arteaga (1731-1783). A year later, Spain established a military post, San Lorenzo de Nutka, at Yuquot in 1789 which existed until 1795. The missionaries who arrived with the sailors were urged to learn the vernacular languages in order to evangelize. In chapter 5 of the
Bidirectional Associations Between Mothers’ and Fathers’ Parenting Consistency and Child BMI
Authors: Jansen Pauline W. , Giallo Rebecca , Westrupp Elizabeth M. , Wake Melissa , Nicholson Jan M. 
Published: November 2013

BACKGROUND:
Research suggests that general parenting dimensions and styles are associated with children’s BMI, but directionality in this relationship remains unknown. Moreover, there has been little attention to the influences of both mothers’ and fathers’ parenting. We aimed to examine reciprocal relationships between maternal and paternal parenting consistency and child BMI.

METHODS:
Participants were 4002 children and their parents in the population-based Longitudinal Study of Australian Children. Mothers and fathers self-reported parenting consistency, and children’s BMI was measured at 4 biennial waves starting at age 4 to 5 years in 2004. Bidirectionality between parenting and child BMI was examined by using regression analyses in cross-lagged models.

RESULTS:
The best-fitting models indicated a modest influence from parenting to child BMI, whereas no support was found for bidirectional influences. For mothers, higher levels of parenting consistency predicted lower BMI in children from Waves 1 to 2 and 3 to 4; for example, for every SD increase in mothers’ parenting consistency at Wave 1, child BMIz fell by 0.025 in Wave 2 (95% confidence interval: −0.05 to −0.003). For fathers, higher levels of parenting consistency were associated with lower child BMI from Waves 1 to 2 and 2 to 3.

CONCLUSIONS:
Parenting inconsistency of mothers and fathers prospectively predicted small increases in offspring BMI over 2-year periods across middle childhood. However, child BMI did not appear to influence parenting behavior. These findings support recent calls for expanding childhood overweight interventions to address the broad parenting context while involving both mothers and fathers.
Incidence of Obesity Among Young US Children Living in Low-Income Families, 2008–2011
Authors: Pan Liping , May Ashleigh L. , Wethington Holly , Dalenius Karen , Grummer-Strawn Laurence M. 
Published: November 2013

OBJECTIVE:
To examine the incidence and reverse of obesity among young low-income children and variations across population subgroups.

METHODS:
We included 1.2 million participants in federally funded child health and nutrition programs who were 0 to 23 months old in 2008 and were followed up 24 to 35 months later in 2010–2011. Weight and height were measured. Obesity at baseline was defined as gender-specific weight-for-length ≥95th percentile on the 2000 Centers for Disease Control and Prevention growth charts. Obesity at follow-up was defined as gender-specific BMI-for-age ≥95th percentile. We used a multivariable log-binomial model to estimate relative risk of obesity adjusting for gender, baseline age, race/ethnicity, duration of follow-up, and baseline weight-for-length percentile.

RESULTS:
The incidence of obesity was 11.0% after the follow-up period. The incidence was significantly higher among boys versus girls and higher among children aged 0 to 11 months at baseline versus those older. Compared with non-Hispanic whites, the risk of obesity was 35% higher among Hispanics and 49% higher among American Indians (AIs)/Alaska Natives (ANs), but 8% lower among non-Hispanic African Americans. Among children who were obese at baseline, 36.5% remained obese and 63.5% were nonobese at follow-up. The proportion of reversing of obesity was significantly lower among Hispanics and AIs/ANs than that among other racial/ethnic groups.

CONCLUSIONS:
The high incidence underscores the importance of early-life obesity prevention in multiple settings for low-income children and their families. The variations within population subgroups suggest that culturally appropriate intervention efforts should be focused on Hispanics and AIs/ANs.
Gas Migration Prevention Using Hydroxypropylmethylcellulose as a Multifunctional Additive in Oil Well Cement Slurry
Authors: Abbas Ghulam , Irawan Sonny , Kumar Sandeep , Khan Muhammad Nisar , Memon Shuaib 
Published: November 2013

Abstract
This paper introduces Hydroxypropylmethylcellulose (HPMC) polymer, first time ever as a multifunctional additive for oil well cementing applications. This work is demonstrated by laboratory experiments. In which, API properties of HPMC based cement slurries were determined. From these experimental results, HPMC polymer effectively controlled fluid loss of cement slurry up to the temperature of 190 °F. HPMC completely prevented free water and it has excellent rheology at ambient and high temperatures. In addition, HPMC was found to develop an impervious barrier for prevention of gas migration. Further it was quantified by cement hydration analyzer. It was confirmed that HPMC based cement slurry was gas-tight formation. Such as pore pressure was remained constant at 16 psi with continues injection of gas at 150 psi for 08 hours. In addition, thickening time was increased 3:23 to 5:54 hours by the addition of HPMC polymer in cement slurry. The gas migration prevention was also confirmed through transition time of cement slurry. That was obtained as less than 30 minutes, which is excellent for gas migration prevention according to API criteria. Meanwhile, compressive strength was improved at 0.20 to 0.40 gallon per sack of HPMC polymer in cement slurries at 190 °F. This study showed that HPMC performed as an effective multifunctional additive and overall decreasing the quantity of additives in cement slurry. HPMC polymer comprehensively improved the properties of cement slurry. Thus, it can be effectively used as gas migration preventer at high temperature in field applications.
Determination of iron by Z-GFAAS and the influence of short-term precision and long-term precision
Authors: Andersen Jens 
Published: November 2013

Abstract
A detailed method validation of graphite-furnace atomic absorption spectrometry (GFAAS) with Zeeman background correction was performed. The aim is to perform a detailed investigation of short-term precision as opposed to long-term precision. It was suggested that release of graphite flakes into the light path during measurement significantly influenced the performance of the method. It was found that significant deviations with respect to the certified values were frequent and an estimate of reliable uncertainties was obtained only after a high number of repetitions. Uncertainty of Interlaboratory testing was evaluated as a method to estimate uncertainties that are comparable to uncertainties that were obtained by Interlaboratory testing and to uncertainties predicted by the Horwitz curve. To a large extent, the uncertainty in measurement that was predicted by pooled calibrations corresponded to the uncertainties that were obtained from multiple determinations of unknowns. It was thus proposed that a large proportion of the difference in uncertainty in measurement between laboratories could be explained by properties of the different detectors. In order to support accuracy, it is suggested that a higher level of uncertainty should be accepted in analytical investigations.
Copper-cobalt ferrites as catalysts for methanol decomposition
Authors: Velinov Nikolay , Koleva Kremena , Tsoncheva Tanya , Paneva Daniela , Manova Elina , Tenchev Krassimir , Kunev Boris , Genova Izabela , Mitov Ivan 
Published: November 2013

Abstract
Copper-cobalt ferrites with composition Cu1−xCoxFe2O4, where x= 0.2 and 0.8 were prepared by thermal treatment of co-precipitated precursor. The obtained materials were characterized by TG-DSC, XRD, Transmission and Conversion Electron Mössbauer spectroscopy and temperature programmed reduction with hydrogen. The catalytic properties of ferrites were tested in methanol decomposition to CO and hydrogen.
Influence of temperature on the reduction kinetics of Bi(III) ion in the presence of cystine in chlorate (VII) solutions of decreased water activity
Authors: Nosal-Wiercińska Agnieszka 
Published: November 2013

Abstract
The results of the kinetic measurements of Bi(III) electroreduction on a mercury electrode in 1–8 mol dm−3 chlorate (VII) solutions and in the presence of cystine demonstrate a dependence of the process on the temperature. The applied electrochemical techniques (DC polarography, cyclic and SWV voltammetry) allowed for the determination of the kinetic and thermodynamic parameters and their correlation with water activity. The catalytic activity of cystine was confirmed by the decrease in overall enthalpies of activation. The changes in the values of ΔH
≠ and ΔS
0 for Bi(III) electroreduction in the presence of cystine with the increase of chlorate (VII) concentration showed that the mechanism is different in solutions with low water activity as compared to those with high water activity. Probably it is connected with a different structure of the activated complexes (Bi-Hg(SR)2), mediating electron transfer.
Les trajectoires de passage à l’âge adulte en Europe
Authors: Ferreira Vitor Sérgio , Nunes Cátia 
Published: November 2013

Becoming an adult across Europe : portraying different pathways of youth transitions.
The de-standardization of life course transitions seems to be a convergent and relatively widespread phenomenon across the European space. Longer and more extended timings to reach traditional markers of passage -such as residential and financial autonomy, marriage or having children -have been characterizing the process of becoming an adult. However, there has been cross-national evidence that suggests the existence of different transitional experiences. This article aims to identify different pathways regarding transition to adulthood across Europe and to what extent these pathways reflect the different regimes of youth
transition nationally institutionalized. Moreover, it intends to discuss to what extent the de-standardization trend also reflects patterns of de-ritualization
of the traditional social markers of passage to become an adult, by evaluating their ritualistic value. Using data from the European Social Survey -Round 3 (2006) and specifically focusing on the rotating module on the timing of life : the organization of the life course, it will present and discuss results regarding the experiences and the symbolic value of events traditionally perceived as being important in becoming an adult, namely : first fulltime job, leaving the parents’ house, first conjugal experience and first child. Differences between and within countries were found, presenting a diverse patterning of pathways and attitudes on becoming an adult across European societies.
Nouveaux pauvres, nouvelles politiques
Authors: Duvoux Nicolas 
Published: November 2013

New poor, new politics.
Over the past three decades, poverty has again become a structural reality in French society. The «wage society » of the 30 boom years after World War II might have eradicated poverty, but mass unemployment and the flexibility of employment have led to a decided lack of security in modern society. This article studies objective developments of poverty and focuses particularly on their impact on the job market. It also covers institutional responses to the lack of security among wage-earners.