bluuebunny/crossref_metadata_2025_split huggingface dataset:
Systematic surveillance of SARS-CoV-2 reveals dynamics of variant mutagenesis and transmission in a large urban population
Authors: Wrana Jeff , Aynaud Marie-Ming , Caldwell Lauren , Al-Zahrani Khalid , Barutcu Seda , Chan Kin , Obersterescu Andreea , Ogunjimi Abiodun , Jin Min , Zakoor Kathleen-Rose , Patel Shyam , Padilla Ron , Jen Mark , Veniegas Princess Mae , Dewsi Nursrin , Yonathan Filiam , Zhang Lucy , Ayson-Fortunato Amelia , Aquino Analiza , Mazzulli Tony , Krzyzanowski Paul , Simpson Jared , Bartlett John , Lungu Ilinca , Poutanen Susan , Pelletier Laurence , Gekas Michael , Wouters Bradly , Rini James 
Published: August 2024

Abstract

Highly mutable pathogens generate viral diversity that impacts virulence, transmissibility, treatment, and thwarts acquired immunity. We previously described C19-SPAR-Seq, a high-throughput, next-generation sequencing platform to detect SARS-CoV-2 that we deployed to systematically profile variant dynamics of SARS-CoV-2 for over 3 years in a large, North American urban environment (Toronto, Canada). Sequencing of the ACE2 receptor binding motif and polybasic furin cleavage site of Spike in over 70,000 patients revealed that population sweeps of canonical variants of concern (VOCs) occurred in repeating wavelets. Furthermore, we found that subvariants and putative quasi-species with alterations characteristic of future VOCs and/or predicted to be functionally important arose frequently, but always extinguished. Systematic screening of functionally relevant domains in pathogens could thus provide a powerful tool for monitoring spread and mutational trajectories, particularly those with zoonotic potential.
Unveiling the true nanostructure of carbon nitride-supported single-atom catalysts
Authors: Vilé Gianvito , Allasia Nicolò , Xu Shuai , Jafri Sadaf Fatima , Borfecchia Elisa , Cipriano Luis A. , Terraneo Giancarlo , Tosoni Sergio , Mino Lorenzo , Liberto Giovanni Di , Pacchioni Gianfranco 
Published: August 2024

Abstract

Single-atom catalysts (SACs) are gathering significant attention in chemistry due to their unique properties, offering uniform active site distribution and enhanced selectivity. However, their precise structure often remains unclear, with multiple models proposed in the literature. Understanding the coordination environment of the active site at the atomic level is crucial for explaining catalytic activity. Here, we present a comprehensive study of SACs made of carbon nitride (CNx) containing isolated nickel atoms. Using a combination of synthesis techniques and characterization methods including Fourier-transform infrared (FT-IR) spectroscopy, X-ray absorption spectroscopy (XAS), and density functional theory (DFT) calculations, we have investigated the local environment of nickel active centres in CNx-supported SACs. Our results challenge conventional structural models and propose a new architecture that better aligns with current experimental evidence. This new structure serves as a foundational step towards a rational approach to catalyst development and can facilitate more precise design and application of these innovative catalysts.
Overview of perianeurysmal edema after the endovascular management of cerebral aneurysms. A pooled analysis of 48 cases.
Authors: Azab Mohammed A. , Hamid  , Atallah Oday 
Published: August 2024

Abstract

Background:
Perianeurysmal edema occurring after endovascular treatment for cerebral aneurysms is uncommon compared to surgical clipping. The clinical aspects and the exact explanation is poorly understood.
Methods:
We searched PubMed, Google Scholar, Web of Science. We used the following keywords “endovascular management of cerebral aneurysms” “perianeurysmal cerebral edema”, perianeurysmal cerebral edema after endovascular treatment endovascular treatment” “intracranial aneurysms with perianeurysmal edema” “vessel wall enhancement after endovascular therapy”. For each case, demographic, clinicopathological, therapeutic and follow-up data were gathered and analyzed.
Results:
Perianeurysmal edema after endovascular treatment has a clear female predilection, with a male: female ratio of (12 (25%):29 (60.41%)). The average time from EVT to the onset of edema ranged from one day to about eight years. The aneurysm dimension ranged from 6.8 to 25 mm as the largest size reported. Most patients were asymptomatic 18(37.5 %), and headache was the presenting symptom in 10 patients (20.8%). Aneurysmal wall enhancement was reported in (16 (33.3 %)) patients with perianeurysmal edema. About 12 patients (25%) developed post EVT hydrocephalus. The most common coil used was the platinum type 31 (64.58%). Most of the patients were treated expectantly with follow up 17 (35.41 %), while steroids were used only in 14 (29.16%) patients. Most of the patients have their edema resolved 29 (60.41%) or stable 9 (37.5%).
Conclusion:
There is growing evidence supporting the incidence of post embolization inflammatory reactions involving the vessel wall and the surrounding parenchyma, however, the exact clinical perspectives and the predisposing factors are not fully uncovered. This analysis highlights the possible presentations, and short term outcome of patients presenting with perianeurysmal edema after endovascular management of cerebral aneurysms.
Trends and Excess Risk of Place of Delivery for Under-five Mortality in Ethiopia: A Trend Analysis of the Ethiopian Demographic and Health Survey Data from 2000-2019
Authors: Hailu Getachew , Abeje Gedefaw , Asemahagn Mulusew Andualem 
Published: August 2024

Abstract

BackgroundThe place of delivery plays a crucial role in the survival of neonates. Following the recommendation that giving birth at a health facility is safer than giving birth at home, health facility delivery increased from 26% in 2016 to 48% in 2019. However, neonatal mortality increased from 29 in 2016 to 33 per 1,000 live births in 2019 in Ethiopia. Hence, this study aimed to analyze the trends and disparities in risk differences according to place of delivery for mortality in children under five years of age in Ethiopia.MethodsThis study used five years of nationally representative demographic and health survey data. The Child and Birth Recode data files were accessed as electronic versions in STATA file format. A modified DHS_U5_rates shared code of chap08_CM was used to save the number of deaths and at-risk individuals for the eight age intervals. Then, we calculated the number of deaths, at-risks, and mortality rates for home- and facility-born children using the Stata command “collapse (sum)” for neonates, post-neonates, infants, children, and under-fives. The trends and disparities in mortality according to place of delivery are presented with line graphs and tables. The mortality difference (RD) at the place of delivery with a 95% uncertainty level was calculated using the “csi”STATAcommand.ResultsThe excess risk difference of 12.7 under five mortality rates [RD=12.66, 95%CI: 3.27, 22.05] in 2016, 7.24 child mortality rate (CMR) [RD=7.24, 95%CI: 1.53, 12.95] in 2019, 14 infant mortality rate (IMR) [RD=13.95, 95%CI: 8.39, 19.52] for all survey years in total, 11 post-natal mortality rate (PNMR) [RD=11.22, 95%CI:6.44, 16] in 2016, and 7 PNMR [RD=7.34, 95%CI: 1.13, 13.56] in 2019 per 1000 live births might be attributable to home birth. However, the negative risk difference of -16.02 neonatal mortality rate (NMR) [RD= -16.02, 95%CI: -29.20, -2.84] in 2011 and -8.51 NMR [RD= -8.51, 95%CI: -16.23, -0.79] in 2016 per 1000 live births might indicate neonates born at home had reduced risk of death than those born at health facility.ConclusionThe difference in the risk of excess U5MR, CMR, IMR, and PNMR per 1000 live births among children born at home might be attributed to their home delivery. These excess deaths would have been prevented if children born at home had the same risk of death as children born at health facilities. However, the difference in the risk of bias associated with NMR might indicate that neonates born at home have a lower risk of death than neonates born at health facilities; this possibility requires further investigation with contextual characteristics as well as access to emergency neonatal health care services.
Teacher Candidates’ Epistemic Reflexivity about Elementary Science Instruction
Authors: Foss James 
Published: August 2024

Abstract

Knowledge of science and engineering practices remain a priority in the U.S. (NASEM, 2021) and internationally (Allen et al., 2021). Moreover, scientific thinking is recognized as necessary for a healthy and equitable society (NASEM, 2021). This positions educators to prepare students with a scientific skill set via complex methods (NSTA, 2020), yet research documents elementary teachers lack confidence in their training and knowledge necessary to teach science (Nowikowski, 2017). Therefore, pre-service training is an ideal context to introduce a practical heuristic for thinking critically about science instruction. Epistemic education recently established new directions to support teachers to engage in critical evaluation of knowledge that results in action. The construct of epistemic reflexivity offers a pathway to improving views of knowledge and interactions with knowing (Lunn Brownlee, Feucht, & Schraw, 2017). The extant record has not yet explored preservice teachers use of this conceptual frame for critical thinking. This paper reports the results of a pilot study where teacher candidates in a baccalaureate level teacher induction program engaged in epistemic reflexivity to consider the relationship between how knowledge is developed in science by experts and how these ideas may influence how children are taught. This was done through written prompts based on constructs from the (3R-EC) framework for epistemic reflexivity developed by Lunn Brownlee et al. (2019).
Frontiers of Biogeography relaunched with Pensoft Publishers
Authors: Whittaker Robert J. , Franklin Janet , Costello Mark John 
Published: August 2024

Frontiers of Biogeography, the scientific journal of The International Biogeography Society (TIBS), is now being published in partnership with Pensoft Publishers, who provide a sophisticated review and publication platform, enhancing publication and dissemination of scholarly work for authors.
Frontiers of Biogeography has been selected for inclusion in the Web of Science™.
The International Biogeography Society is committed to the growth and success of Frontiers of Biogeography as a service to biogeographical science.
Frontiers of Biogeography will continue to support low cost, high quality, high visibility, open-access publishing for biogeographers.
Groundwater quality assessment for drinking, irrigation purposes and fuzzy logic-based water quality index for industrial suitability in Walajapet taluk, Ranipet district, Tamil Nadu, India
Authors: Loganathan Sankar , Sathiyamoorthy Mahenthiran 
Published: August 2024

ABSTRACT

Ranipet district in Tamil Nadu is one of the major industrial zones in India. Groundwater has been extensively used in this region for drinking, agricultural, and industrial purposes. For finding the groundwater quality, representative samples have been collected in the premonsoon (PRM) and postmonsoon (POM) seasons of 2023 and analysed for major physicochemical parameters. The drinking suitability was analysed based on drinking water quality index, and it showed that 68.52 and 70.37% of samples from the PRM and POM seasons are classified as poor groundwater for drinking. The groundwater's suitability for irrigation was analysed based on various irrigation quality indices, and it highlighted that most of the groundwater was suitable for agriculture. Industrial suitability was determined by several industrial quality indices. Due to the simultaneous application of several indices, a sample is categorised into many water quality groups, introducing bias into handling and decision-making. The Mamdani fuzzy inference system creates a unique integrated industrial water quality index to address this issue. The index revealed that only 24.07 and 9.26% of samples from the PRM and POM seasons, respectively, were free of corrosion or scaling, while the remaining samples were inappropriate for industrial use.
De (on)tembare Noordzee
Authors: van Dooren Korneel , Fias Mona 
Published: August 2024

Doorheen de eeuwen hebben we een gelaagde relatie opgebouwd met de zee. Terwijl haar onstuimigheid ontzag inboezemt, biedt ze ook volop kansen. De klimaatverandering dwingt ons echter onze relatie met de zee te herzien. In dit AGORA nummer belichten we een aantal sociaalruimtelijke processen die daarmee gepaard gaan.
Enhancing the Role of Posyandu Cadres in Early Detection and Support for High-Risk Pregnant Women through a Psychoeducation Approach
Authors: Meo Maria Lupita Nena , Rotty Monique Priscilla Fransiska , Mapaly Heilbert Armando 
Published: August 2024

Introduction: High-risk pregnancies are a major cause of maternal morbidity and mortality, both on a global and national scale. Tuminting Public Health Center, which is a partner in the Community Partnership Empowerment activities, has a significant number of patients with high-risk pregnancies. This indicates an urgent need for the care of high-risk pregnant women. Pregnant women with high-risk pregnancies require priority and continuous care, including early screening/detection, monitoring, and support. However, a situation analysis at the partner site has identified several issues, including: 1) Posyandu cadres are not actively involved in supporting high-risk pregnant women, resulting in these women not receiving appropriate healthcare for their pregnancy conditions. 2) Health promotion media for high-risk pregnant women is limited, preventing these women from receiving accurate health information tailored to their condition. The objectives of these activities are to enhance the role of cadres in supporting high-risk pregnant women and to improve the availability of health promotion media as a support tool for cadres in their role. Methods: To address these issues, the proposers offer the following solutions: 1) Training on early detection, monitoring, and support for posyandu cadres using a psychoeducational approach.2) Training on the use of digital media for health promotion for high-risk pregnant women for cadres. Results: This training was attended by 37 cadres at Tuminting Public Health Center. Participants' knowledge levels were evaluated before and after the activity. The evaluation of these activities showed a p-value of 0.000, indicating that there was a difference in the knowledge of the training participants before and after the training. Conclusion: Training activities with a psychoeducational approach can improve the knowledge of cadres, enabling them to enhance their role in early detection and support for high-risk pregnant women.
Upaya Meningkatkan Hasil Belajar Matematika melalui Model Pembelajaran Problem Based Learning Berbantuan Media Powerpoint Interaktif
Authors: Retnaningtiyas Agustina , Sanoto Herry 
Published: August 2024

Rendahnya hasil belajar siswa dalam muatan pelajaran matematika. Tujuan dari penelitian ini adalah untuk menganalisis model Problem Based Learning (PBL) berbantuan media powerpoint interaktif untuk meningkatkan hasil belajar matematika siswa kelas IV SD. Jenis penelitian yang digunakan adalah Penelitian tindakan kelas dilaksanakan dalam dua siklus. Setiap siklus dilaksanakan dalam tiga tahap yaitu Look, Think, dan Act. Subjek penelitian kelas IV berjumah 16 siswa yang terdiri dari 14 siswa laki-laki dan 12 siswa perempuan. Pengumpulan data yang digunakan adalah tes evaluasi, wawancara, observasi dan dokumentasi, kemudian dianalisis dengan menggunakan cara deskriptif kualitatif dan kuantitatif. Hasil belajar pada pra siklus dengan persentase 26,92% atau 7 siswa yang tuntas dan memperoleh rata-rata 48,5, kemudian meningkat pada siklus I dengan persentase 61,54% atau 16 siswa yang tuntas dan memperoleh rata-rata 70,38. Selanjutnya meningkat lagi pada siklus II dengan persentase 88,46% atau 23 siswa yang tuntas dan memperoleh rata-rata 85,57. Simpulan penelitian bahwa dengan menerapkan model Problem Based Learning berbantuan media powerpoint interaktif dapat meningkatkan hasil belajar matematika siswa kelas IV SD. Implikasi dalam proses pembelajaran khususnya pada mata pelajaran matematika agar mampu menciptakan suasana belajar yang kondusif dapat dilakukan dengan menggunakan media pembelajaran powerpoint interaktif sebagai salah satu alternatif dalam membatu proses pembelajaran.
Upaya Peningkatan Penguasaan Kosakata dan Keterampilan Berbicara Melalui Metode Bercerita dengan Menggunakan Media Boneka Tangan pada Mata Pelajaran Bahasa Indonesia
Authors: Destyani Early regina , Herry Sanoto  
Published: August 2024

Penelitian ini dilatarbelakangi karena siswa masih belum lancar berbicara serta belum mampu menyampaikan ide, pikiran, gagasan, dan perasaan lewat komunikasi lisan, sehingga berdamapk terhadap rendahnya keterampilan berbicara siswa. Maka penelitian ini dilakukan yang bertujuan untuk meningkatkan penguasaan kosakata dan keterampilan berbicara siswa melalui media boneka tangan. Jenis penelitian ini adalah penelitian tindakan kelas kolaboratif dengan menggunakan model Kemmis dan Mc Taggart dengan dua siklus, dengan subjek penelitian sebanyak 22 peserta didik. Objek penelitian ini adalah penguasaan kosakata dan keterampilan berbicara peserta didik. Teknik pengumpulan data menggunakan teknik observasi, dokumentasi dan wawancara. Teknik analisis data dilakukan secara deskriptif kualitatif dan kuantitatif. Berdasarkan hasil penelitian menunjukkan bahwa capaian penguasaan kosakata yang dilakukan pada Pra Siklus mencapai 40,90%, pada Siklus I mencapai 64,00% dan Siklus II mencapai 91,00%. Sedangkan capaian keterampilan berbicara pada Pra Siklus 45,40%, pada Siklus I mencapai 69,00% dan Siklus II mencapai 88,00%. Sehingga dapat disimpulkan bahwa penerapan media boneka tangan dapat meningkatkan penguasaan kosakata dan keterampilan berbicara dengan kriterian Sangat Baik.
Pemanfaatan Media Pembelajaran Five In One Box Dalam Mengembangkan Kognitif Anak Usia Dini
Authors: Rahayu Titik , Wahidah Finadatul 
Published: August 2024

Five In One Box merupakan salah satu media pembelajaran yang dirancang untuk membantu anak-anak dalam mengenal angka, huruf, dan konsep dasar lainnya melalui berbagai aktivitas yang terintegrasi dalam satu kotak. Media ini dirancang untuk memberikan pengalaman belajar yang menarik dan bermanfaat bagi anak usia dini. Penelitian ini bertujuan untuk mengetahui pemanfaatan media pembelajaran Five In One Box dalam mengembangkan kognitif anak usia dini. Dalam penelitian ini menggunakan pendekatan kualitatif dengan jenis penelitian deskriptif. Teknik pengumpulan datanya menggunakan teknik observasi, teknik wawancara dan teknik dokumentasi. Dengan analisis data yang digunakan adalah dengan langkah reduksi data, display data, dan verifikasi data. Hasil penelitian ini adalah perencanaan pemanfaatan media pembelajaran Five In One Box dalam mengembangkan perkembangan kognitif anak dimulai dengan identifikasi kebutuhan media di KB Dharma Wanita, pemperolehan data, menciptakan alat peraga edukatif dan penyusunan strategi pembelajaran yang termuat dalam modul ajar. Pelaksanaan pemanfaatan media pembelajaran Five In One Box dimulai dengan pengenalan media Five In One Box. Guru KB Dharma Wanita tidak hanya menjadi fasilitator namun juga mengamati, mengarahkan dan membantu peserta didik dalam memahami kegiatan pembelajaran. Evaluasi perkembangan kognitif anak KB Dharma Wanita diukur menggunakan alat ukur yang meliputi tes pengetahuan dasar, kemampuan problem solving, dan kemampuan berpikir logis. Adapun teknik penilaian yang digunakan oleh guru KB Dharma Wanita dalam pemanfaatan media pembelajaran Five In One Box untuk mengembangkan kemampuan kognitif anak usia dini antara lain Observasi, penilaian percakapan, dan portofolio.
METAFORA KONSEPTUAL EMOSI MARAH: STUDI KASUS MASYARAKAT SUKU JAWA DI PROVINSI LAMPUNG
Authors: Pangestuti Dina Agil 
Published: August 2024

Metafora konseptual emosi marah telah dikategorisasikan oleh Kövecses (2003) dalam beberapa bentuk metafora seperti salah satu contoh ANGER IS THE HOT OF A FLUID IN A CONTAINER. Tujuan dari penelitian ini adalah melihat metafora konseptual emosi marah pada penutur Bahasa Indonesia beretnis Jawa di Provinsi Lampung, dengan menerapkan konseptual metafora yang telah dikonsepkan Kövecses (2003). Penelitian ini merupakan studi kasus dengan melibatkan empat partisipan perempuan. Pengambilan data dilakukan dengan mewawancarai partisipan yang sesuai dengan kriteria. Hasil penelitian ini mendukung temuan Kövecses. Namun, peneliti menemukan keunikan metafora konseptual emosi marah yang belum dirumuskan oleh penelitian sebelumnya yang dipahami sebagai objek berupa benda padat yang menyebabkan rasa tidak nyaman di dalam dada. Kata Kunci: Metafora konseptual, emosi marah, perempuan, Jawa
Simbolisasi dan Nilai Moral dalam “Ramayana”
Authors: Malik Muhammad Ardiansah Maulana , Wirajaya Asep Yudha , Wirajaya Asep Yudha 
Published: August 2024

Studi ini bertujuan untuk menggali dan menganalisis simbolisme serta nilai moral yang terkandung dalam karya sastra Jawa Kuno, "Ramayana". Dengan menggunakan pendekatan hermeneutika, penelitian ini menyelidiki berbagai elemen simbolik yang tersembunyi dalam narasi dan bagaimana elemen-elemen ini berkontribusi pada pembentukan nilai moral dan budaya masyarakat Jawa kuno. Penelitian ini juga membahas perbandingan antara versi Jawa Kuno dan versi lain dari epos Ramayana, untuk menyoroti keunikan interpretasi lokal dan pengaruhnya terhadap nilai-nilai sosial dan budaya. Hasil penelitian menunjukkan bahwa Ramayana versi Jawa tidak hanya merupakan karya sastra yang menghibur, tetapi juga sarana pendidikan moral dan spiritual yang mencerminkan kebijaksanaan serta filosofi hidup masyarakat Jawa kuno. Penelitian ini memberikan wawasan baru tentang pentingnya simbol dan moral dalam sastra klasik Jawa, serta kontribusinya terhadap pembentukan identitas budaya dan nilai-nilai masyarakat. Kata kunci: Simbolisasi, Nilai Moral, Ramayana
KECEMASAN TOKOH NISKALA DALAM FILM KU KIRA KAU RUMAH KAJIAN PSIKOANALISIS
Authors: Maghfiroh Erisa Faridatul , Darmadi Renalita Adesyah Putri , Apriliany Yeppi , Nugroho Abdillah 
Published: August 2024

Tujuan penelitian ini untuk mendeskripsikan karakteristik dan kecemasan tokoh Niskala dalam film Ku Kira Kau Rumah menggunakan kajian psikoanalisis. Metode penelitian kualitatif deskriptif digunakan dalam penelitian ini. Menggunakan dua teknik penelitian. Teknik studi kepustakaan yang dilakukan dengan mengintegrasikan referensi yang memiliki fokus sebagai landasan teori yang digunakan. Teori yang digunakan berupa dari seorang pakar bernama Sigmund Freud. Psikoanalisis berangkat dari sebuah ilmu guna menelisik tujuan sebuah sikap psikologis dari manusia. Teknik observasi dengan menganalisis film Kukira Kau Rumah yang dilakukan secara berulang-ulang yang diiringi dengan group discussion guna mendapatkan berbagai perspektif berbagai sudut. Dari data yang telah dikaji terhimpun sepuluh data yang dimana dapat disimpulkan, karakteristik tokoh Niskala yaitu, bipolar, ramah, introvert, dan koleris. Para pemeran pendukung turut menonjolkan tokoh Niskala dengan sifat dan sisi kecemasan yang dimilikinya. Atau dapat dikatakan sutradara mengemas film dengan apik hingga rasa sampai kepada pononton atau penikmat film. Kecemasan tokoh Niskala dalam film tersebut terdapat, kecemasan realistik, kecemasan neurotik, dan kecemasan moral.