bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sistem Penyiraman Otomatis berbasis Arduino Pada Kebun Tomat Menggunakan Sensor Soil Moisture
Authors: Dimas Rizky Putra Pratama  , Nunu Nugraha Pratama  , Muhamad Riyad Ariwibowo  
Published: July 2024

Tanah merupakan media tumbuh tanaman yang memiliki kandungan mineral tanah yang dapat mempengaruhi kondisi tanah tersebut, di antaranya suhu dan kelembapan tanah. Kondisi tanah yang baik mempunyai nilai kelembapan di atas 50%-80%. Selain kelembapan tanah faktor lain yang mempengaruhi pertumbuhan tanaman salah satunya yaitu suhu, Suhu tanah yang ideal bagi sebagian jenis tumbuhan berada di kisaran 20ºC hingga 35ºC ,Tanaman tomat bisa tumbuh dengan baik dengan minimal kondisi kelembapan tanah di atas 50%,. Oleh karena itu dibutuhkannya pengujian untuk mengetahui kondisi tanah tersebut, dengan cara membuat sistem penyiraman otomatis berbasis arduino menggunakan sensor soil moisture. Hasil pengujian pada sensor soil moisture menunjukkan bahwa kondisi tanah yang ideal ada pada waktu malam hari, dengan rata rata setiap sensor yang digunakan yaitu 66,92 %, 60,19 %, 61,81%, 66,86%, sehingga pengujian sensor pH memperoleh nilai rata rata error 3,89 %, serta nilai pengujian sensor water flow dengan nilai rata rata 7,828 L/min.
Media Disc Triage Assessment on Improving Triage Skills Using the Australasian Triage Scale (ATS) on Students of Kusuma Husada University Surakarta
Authors: Rosida Nikma Alfi , Afni Annisa Cindy Nurul , Rahmad Muhamad Nur 
Published: July 2024

ABSTRACT The Australasian Triage Scale (ATS) is a tool used by triage officers in the emergency department to assess patient severity and prioritize services based on the severity of the patient's condition. To evaluate the effectiveness of using learning tools in the form of Disc Triage Assessment as a learning medium in improving understanding and accuracy in determining triage by nursing students in using ATS triage. The Community Service method used is quasi-experimental with a pre-post test without control design. Community Service will be carried out on Nursing Study Program Students, Diploma Three Program, Faculty of Health Sciences, Kusuma Husada University. Data analysis was performed using the Wilcoxon test. The pretest results showed that the moderate category was 1 respondent (3.1%) and the poor category was 31 respondents (96.9%). The posttest results with the Good category were 3 respondents (9.4%) and the Fair category were 5 respondents (75.0%). The results of the use of Disc Triage Assessment media show that the p-value is 0.016 (<0.05) which means that there is an effect of Disc Triage Assessment Media on Skills to Determine Australasian Triage Scale (ATS) on Students of Kusuma Husada University Surakarta. Keywords: Media Disc Triage Assessment, Triage skills, Australasian Triage Scale (ATS)
Penerapan Terapi Bermain Mewarnai Pada Anak Prasekolah Yang Mengalami Kecemasan Hospitalisasi
Authors: Amalia Luthfiana , Irdawati Irdawati , Putri Rosalia Dian Arsita 
Published: July 2024

ABSTRACT Hospitalization of children is a procedure that requires children to be in health services to receive medical treatment until their condition recovers and they are allowed to go home. The reaction of preschool-aged children during the treatment period is anxiety. Anxiety occurs because the child feels a traumatic situation because he is separated from his daily environment. Coloring play therapy is an effective game option for children to play during their hospital stay. Applying coloring play therapy to reduce anxiety in children who are hospitalized. This case study uses a nursing care approach by applying coloring play therapy for 30 minutes given to three preschool age children who experienced anxiety due to hospitalization as measured using the Faces Anxiety Scale (FAS). Coloring play therapy was proven to reduce the anxiety scale in pre-school children due to hospitalization. Play therapy intervention can reduce anxiety in children undergoing hospitalization so that children become cooperative in receiving nursing actions Keywords : Coloring play therapy, Anxiety, Preschool Children ABSTRAK Hospitalisasi pada anak merupakan prosedur yang mengharuskan anak berada di pelayanan kesehatan untuk mendapat perawatan medis hingga kondisi pulih dan diperbolehkan pulang. Reaksi anak usia preschool selama masa perawatan adalah kecemasan, kecemasan terjadi karena anak merasakan situasi traumatis karena terpisah dari lingkungan sehari-hari. Terapi bermain mewarnai menjadi salah satu pilihan permainan yang efektif untuk dilakukan anak saat masa perawatan di rumah sakit. Menerapkan terapi bermain mewarnai untuk mengurangis kecemasan pada anak yang mengalami hospitalisasi. Studi kasus ini menggunakan pendekatan asuhan keperawatan dengan menerapkan terapi bermain mewarnai selama 30 menit yang diberika pada tiga anak usia prasekolah yang mengalami kecemasan akibat hospitalisasi yang diukur menggunakan Faces Anxiety Scale (FAS). Terapi bermain mewarnai terbukti menurunkan skala kecemasan pada anak usia pra sekolah akibat hospitalisasi. Intervensi terapi bermain dapat menurunkan kecemasan pada anak yang menjalani hospitalisasi sehingga anak menjadi kooperatif menerima tindakan keperawatan Kata kunci: Terapi Bermain mewarnai, Kecemasan, Anak Prasekolah
Analisis Faktor yang Berhubungan dengan Kanker Payudara Pada Wanita di Klinik Bintang Ki Maja Lampung
Authors: Fadhila Syifa Rahmi , Karyus Aila , Setiaji Bambang , Irianto Sugeng Eko , Za'im Ammar , Nonasri Fitra Galih 
Published: July 2024

ABSTRACT Breast cancer is the first contributor to cancer in women in Indonesia. The early detection rate for breast cancer in Bandar Lampung City in 2022 through the SADANIS examination is quite low (40.8%), the prevalence of breast cancer in Bandar Lampung City is high. Bintang Ki Maja Clinic founded by oncology surgeons, has a community of breast cancer sufferers “Komunitas Tetap Semangat”. To examining factors related to the incidence of breast cancer in women at the Lampung Bintang Ki Maja Clinic in 2024. This research is a quantitative research with a case control design. The minimum sample size is 100 people, using consecutive sampling technique. Data were collected using a breast cancer risk factors and smoking behavior questionnaires, then analyzed and presented in univariate, bivariate and multivariate analysis, using chi square and binary logistic regression. Age at first pregnancy (p=0.021), hormonal contraception use (p=0.003), family history (p=0.021), and smoking behavior (p=0.025) were associated with the incidence of breast cancer and the dominant factor is hormonal contraception use (OR 4.872). Hormonal contraceptive use, family history, and smoking behavior are related to the incidence of breast cancer and hormonal contraceptive use is the dominant factor. Keywords: Breast Cancer, Hormones, Women of Childbearing Age ABSTRAK Kanker payudara menjadi penyumbang pertama kanker pada wanita di Indonesia. Angka deteksi dini kanker payudara di Kota Bandar Lampung tahun 2022 melalui pemeriksaan SADANIS cukup rendah (40,8%), sehingga prevalensi kejadian kanker payudara di Kota Bandar Lampung masih tinggi. Klinik Bintang Ki Maja yang didirikan oleh dokter spesialis bedah onkologi memiliki komunitas penderita kanker payudara “Komunitas Tetap Semangat”. Untuk meneliti faktor-faktor yang berhubungan dengan kejadian kanker payudara pada wanita di Klinik Bintang Ki Maja Lampung tahun 2024. Penelitian ini menggunakan desain case control. Jumlah sampel minimal 100 orang diambil dengan teknik consecutive sampling. Pengambilan data dilakukan menggunakan kuesioner faktor risiko kanker payudara dan perilaku merokok, kemudian dianalisis, dan disajikan dalam analisis univariat, bivariat, dan multivariat, menggunakan chi square dan regresi logistik ganda. Faktor usia pada kehamilan pertama (p=0,021), pemakaian kontrasepsi hormonal (p=0,003), riwayat keluarga (p=0,021), dan perilaku merokok (p=0,025) berhubungan dengan kejadian kanker payudara. Faktor yang dominan berhubungan dengan kejadian kanker payudara pada wanita di Klinik Bintang Ki Maja Lampung adalah pemakaian kontrasepsi hormonal (OR 4,872). Faktor pemakaian kontrasepsi hormonal, riwayat keluarga, dan perilaku merokok berhubungan dengan kejadian kanker payudara dengan faktor yang dominan berhubungan adalah pemakaian kontrasepsi hormonal. Kata Kunci: Hormon, Kanker Payudara, Wanita Usia Subur
Generation of lysolipin derivatives by genetic engineering
Authors: Robertsen Helene , Rohrer Sabrina , Kulik Andreas , Wohlleben Wolfgang , Mast Yvonne 
Published: July 2024

Lysolipin I is a halogenated, polycyclic xanthone natural product belonging to the polyketide class of antibiotics, naturally produced by Streptomyces violaceoniger TÜ96 and Streptomyces tendae TÜ4042. The biosynthesis is encoded on a 43 kb-spanning biosynthetic gene cluster. Heterologous expression of the gene cluster has been established in previous work by using the cosmid 4H04, which was transferred to Streptomyces albus. In the current study, we demonstrate the optimization of production yields of therapeutically interesting lysolipin derivatives with extended activity against Gram-negatives and less cytotoxic bioactivities, respectively, by using mutated heterologous S. albus producer strains. Production yields were significantly increased by adapting cultivation conditions as well as by inactivating the transcriptional repressor gene llpRI, which lead to increased and consistent lysolipin (derivatives) production. Furthermore, cultivation of a S. albus 4H04∆llpOI mutant strain in bromide-containing fermentation medium resulted in the production of a new brominated lysolipin derivative (C28H20BrNO9).
Good learning environment of medical schools is an independent predictor for medical students’ study engagement
Authors: Huang Runzhi , Li Yuanan , Gong Meiqiong , Zhang Wei , Xian Shuyuan , Tang Jieling , Lu Bingnan , Yang Yiting , Jin Minghao , Qian Weijin , Liu Zhenglin , Ma Haonan , Wu Xinru , Yin Huabin , Liu Xin , Zhang Chongyou , Du Erbin , Lin Qing , Huang Zongqiang , Lin Min , Wang Xiaonan , Wang Yue , Chen Wenfang , Liu Yifan , Zhang Jie , Ji Shizhao 
Published: July 2024

BackgroundStudy engagement is regarded important to medical students’ physical and mental wellbeing. However, the relationship between learning environment of medical schools and the study engagement of medical students was still unclear. This study was aimed to ascertain the positive effect of learning environment in study engagement.MethodsWe collected 10,901 valid questionnaires from 12 medical universities in China, and UWES-S was utilized to assess the study engagement levels. Then Pearson Chi-Square test and Welch’s ANOVA test were conducted to find the relationship between study engagement and learning environment, and subgroup analysis was used to eradicate possible influence of confounding factors. After that, a multivariate analysis was performed to prove learning environment was an independent factor, and we constructed a nomogram as a predictive model.ResultsWith Pearson Chi-Square test (p &lt; 0.001) and Welch’s ANOVA test (p &lt; 0.001), it proved that a good learning environment contributed to a higher mean of UWES scores. Subgroup analysis also showed statistical significance (p &lt; 0.001). In the multivariate analysis, we could find that, taking “Good” as reference, “Excellent” (OR = 0.329, 95%CI = 0.295–0.366, p &lt; 0.001) learning environment was conducive to one’s study engagement, while “Common” (OR = 2.206, 95%CI = 1.989–2.446, p &lt; 0.001), “Bad” (OR = 2.349, 95%CI = 1.597–3.454, p &lt; 0.001), and “Terrible” (OR = 1.696, 95%CI = 1.015–2.834, p = 0.044) learning environment only resulted into relatively bad study engagement. Depending on the result, a nomogram was drawn, which had predictive discrimination and accuracy (AUC = 0.680).ConclusionWe concluded that learning environment of school was an independent factor of medical student’s study engagement. A higher level of learning environment of medical school came with a higher level of medical students’ study engagement. The nomogram could serve as a predictive reference for the educators and researchers.
Serum HDL-C subfractions as predictors of cardiovascular calcification in hemodialysis patients: novel insights and clinical implications
Authors: Li Dong-Yun , Sun Wei , Zhou Xiao-Tao , Wen Yu , Zou Yang 
Published: July 2024

ObjectiveThis study aims to explore the relationship between cardiovascular calcification (CVC) and serum levels of high-density lipoprotein cholesterol (HDL-C) and its subfractions in hemodialysis (HD) patients.MethodsHD patients and healthy participants were recruited based on specific inclusion and exclusion criteria. Various blood indicators were measured, and demographic information was recorded. HDL-C particle levels were quantified using lipophilic fluorescent dye staining and capillary electrophoresis (microfluidic platform). Coronary artery calcium scores and valve calcification were used to classify HD patients into calcification and non-calcification groups.ResultsCompared to healthy participants, HD patients showed a significant increase in HDL-C, high-density lipoprotein 2 cholesterol (HDL2-C), and high-density lipoprotein 3 cholesterol (HDL3-C) levels (p &lt; 0.001). Further division of HD patients into calcification and non-calcification groups revealed higher serum HDL3-C concentrations (p = 0.002) and a higher HDL3-C/HDL-C ratio (p = 0.04) in the calcification group. Additionally, elevated HDL3-C levels were found to be an independent risk factor for CVC in HD patients (p = 0.040). The ROC curve analysis showed an AUC value of 0.706 for HDL3-C (p = 0.002).ConclusionOur study indicates that elevated serum HDL3-C levels in HD patients are an independent risk factor for CVC and can serve as a potential predictor for CVC events. However, more studies need to verify its potential as a predictive indicator..
Causal role of immune cells in uveitis: a Mendelian randomization study
Authors: Pu Jianping , Zhao Zhuanghong , Duan Yanping , Lu Jun , Yao Yuchen , Wen Yuxin , Li Yanxun , Zhang Yu , Ye Fengyu 
Published: July 2024

BackgroundUveitis refers to a group inflammation affecting the uvea, retina, retinal blood vessels as well as vitreous body, which is one of the common causes of blindness. There is growing evidence linking different types of immune cells to uveitis, although it remains uncertain if these associations imply causal relationships. Recent advancements in high-density genetic markers like SNPs or CNVs for genotyping, along with the progress in genome-wide association studies (GWAS) technologies, have improved our understanding of the immunological mechanisms involved in ocular diseases. Therefore, our objective was to investigate the potential causal link between immune cells and uveitis using a Mendelian randomization study.MethodsThe exposure and outcome GWAS data for this study were sourced from an open-access database (https://gwas.mrcieu.ac.uk/). Two-sample MR analysis was utilized to evaluate the causal relationship between 731 immune cell features and uveitis. Various MR methods were employed to reduce bias and obtain dependable estimates of the causal link between the immune cell variables and the outcomes. Instrumental variable selection criteria were carefully chosen to enhance the accuracy and efficacy of the causal relationship between different immune cell types and the risk of uveitis.ResultsUsing two-sample MR, IVW modeling showed that GAD had significant effect on immunophenotypes. CD3 levels on CD45RA− CD4+ T cells (OR = 1.087, 95%CI = 1.029 ~ 1.147, p = 0.003) and CD3 levels on CM CD4+ T cells (OR = 1.086, 95%CI = 1.033 ~ 1.141, p = 0.001) were found to be elevated in cases of uveitis. HLA DR levels in CD14− CD16+ monocyte cells (OR = 0.735, 95% CI = 0.635 ~ 0.850, p &lt; 0.001) and HLA DR levels in NK cells (OR = 0.910, 95% CI = 0.851 ~ 0.972, p = 0.005) were observed to be reduced in individuals with uveitis. Furthermore, Two cells were identified to be significantly associated with uveitis risk: HLA DR on in NK cells (OR = 0.938, 95%CI = 0.899 ~ 0.979, p = 0.003), HLA DR on CD14− CD16+ monocytes (OR = 0.924, 95%CI = 0.878 ~ 0.972, p = 0.002).ConclusionThis study highlights the intricate relationship between immune cells and generalized anxiety disorder using genetic methods, offering valuable insights for future clinical investigations.
The Montreal cognitive assessment: normative data from a large, population-based sample of Chinese healthy adults and validation for detecting vascular cognitive impairment
Authors: Wei Qiang , Du Baogen , Liu Yuanyuan , Cao Shanshan , Yin Shanshan , Zhang Ying , Ye Rong , Bai Tongjian , Wu Xingqi , Tian Yanghua , Hu Panpan , Wang Kai 
Published: July 2024

BackgroundThe Montreal Cognitive Assessment (MoCA) is a valuable tool for detecting cognitive impairment, widely used in many countries. However, there is still a lack of large sample normative data and whose cut-off values for detecting cognitive impairment is considerable controversy.MethodsThe assessment conducted in this study utilizes the MoCA scale, specifically employing the Mandarin-8.1 version. This study recruited a total of 3,097 healthy adults aged over 20 years. We performed multiple linear regression analysis, incorporating age, gender, and education level as predictor variables, to examine their associations with the MoCA total score and subdomain scores. Subsequently, we established normative values stratified by age and education level. Finally, we included 242 patients with vascular cognitive impairment (VCI) and 137 controls with normal cognition, and determined the optimal cut-off value of VCI through ROC curves.ResultsThe participants in this study exhibit a balanced gender distribution, with an average age of 54.46 years (SD = 14.38) and an average education period of 9.49 years (SD = 4.61). The study population demonstrates an average MoCA score of 23.25 points (SD = 4.82). The multiple linear regression analysis indicates that MoCA total score is influenced by age and education level, collectively accounting for 46.8% of the total variance. Higher age and lower education level are correlated with lower MoCA total scores. A score of 22 is the optimal cut-off value for diagnosing vascular cognitive impairment (VCI).ConclusionThis study offered normative MoCA values specific to the Chinese adults. Furthermore, this study indicated that a score of 26 may not represent the most optimal cut-off value for VCI. And for detecting VCI, a score of 22 may be a better cut-off value.
Prediction of protein content in paddy rice (Oryza sativa L.) combining near-infrared spectroscopy and deep-learning algorithm
Authors: Yang Ha-Eun , Kim Nam-Wook , Lee Hong-Gu , Kim Min-Jee , Sang Wan-Gyu , Yang Changju , Mo Changyeun 
Published: July 2024

Rice is a staple crop in Asia, with more than 400 million tons consumed annually worldwide. The protein content of rice is a major determinant of its unique structural, physical, and nutritional properties. Chemical analysis, a traditional method for measuring rice’s protein content, demands considerable manpower, time, and costs, including preprocessing such as removing the rice husk. Therefore, of the technology is needed to rapidly and nondestructively measure the protein content of paddy rice during harvest and storage stages. In this study, the nondestructive technique for predicting the protein content of rice with husks (paddy rice) was developed using near-infrared spectroscopy and deep learning techniques. The protein content prediction model based on partial least square regression, support vector regression, and deep neural network (DNN) were developed using the near-infrared spectrum in the range of 950 to 2200 nm. 1800 spectra of the paddy rice and 1200 spectra from the brown rice were obtained, and these were used for model development and performance evaluation of the developed model. Various spectral preprocessing techniques was applied. The DNN model showed the best results among three types of rice protein content prediction models. The optimal DNN model for paddy rice was the model with first-order derivative preprocessing and the accuracy was a coefficient of determination for prediction, Rp2 = 0.972 and root mean squared error for prediction, RMSEP = 0.048%. The optimal DNN model for brown rice was the model applied first-order derivative preprocessing with Rp2 = 0.987 and RMSEP = 0.033%. These results demonstrate the commercial feasibility of using near-infrared spectroscopy for the non-destructive prediction of protein content in both husked rice seeds and paddy rice.
Predictors of fear of COVID-19 in a low-income country: health literacy is important
Authors: Ranjbaran Soheila , Chollou Khalil Maleki , Abedi-Nerbin Salar , Babazadeh Towhid 
Published: July 2024

IntroductionExcessive fear of a threatening condition or situation can result in individuals engaging in unhealthy behaviors, especially during the COVID-19 pandemic. Identifying the influential factors of fear can be effective in designing and implementing health-center interventions to control and reduce the COVID-19 pandemic.MethodsThis study was a cross-sectional design implemented in Iran in 2022. Participants were adults 18–65 years of age recruited randomly from primary Health Care Services Centers (HCSCs) by medical records (n = 380, 64.7% female, mean (SD) age 32.14 ± 10.98 years) in urban and rural areas of the county. The data collection included a demographic form, Fear of COVID-19 questionnaire, Perceived Barriers of COVID-19 preventive behaviors, Self-efficacy, and Health Literacy for Iranian Adults (HELIA) questionnaire.ResultsIt was determined that the fear of COVID-19 showed statistically significant differences according to gender (p-value = 0.013), education level (p-value = 0.001), and job status (p-value = 0.001). According to the hierarchical linear regression, educational level (p-value = 0.001; β = 0.665), job (β = 0.126; p-value = 0.018), self-efficacy (p-value = 0.015; β = 0.103), and Health Literacy (HL) (p-value = 0.001; β = 0.446) were significant predictors of fear of COVID-19. Also, among variables, educational level (p-value = 0.001; β = 0.665) and HL (p-value = 0.001; β = 0.446) were the most important predictors for fear of COVID-19.DiscussionThis research shows that HL has a potential and determinative role in controlling fear of COVID-19. The findings can help healthy policymakers and healthcare providers design HL-based programs in similar epidemics and pandemic situations.