bluuebunny/crossref_metadata_2025_split huggingface dataset:
Necessity for the conservation of drainage systems as last refugia for threatened damselfly species, Coenagrion ornatum
Authors: Harabiš Filip , Dolný Aleš 
Published: October 2014

Abstract

Small streams and rivulets in agricultural landscapes are among the most threatened habitats throughout Europe. Many species occurring primarily within these habitats are listed in the EC Habitats and Species Directive. One example is the damselfly Coenagrion ornatum, which was rediscovered during the last decade in the Elbe Valley (Czech Republic) after more than 40 years. The occurrence of this species, however, was observed only at highly altered sites. Several management attempts, unfortunately, had led to the local extinction instead of strengthening of existing populations, precisely because they ignored the habitat preferences of the target species.

This study analysed the effects of several physiochemical and environmental characteristics of 30 ditch segments in relation to the presence and abundance of C. ornatum.

The occurrence of C. ornatum was found to be positively correlated with the diversity of macrophyte vegetation and negatively with shading. Populations of C. ornatum occurred mostly in smaller, well‐warmed sections of channel, while the species clearly avoided those sections with gravel or concrete substrates.

The results indicate that under certain circumstances, the ongoing utilisation of channels particularly for drainage accords with the objectives of protecting this species and could substitute for routine conservation management activities. Supplementary effective management should focus on removing overgrowing vegetation, eliminating such negative interventions to the channel as strengthening the stream bed, and encouraging the development of rich vegetation along the watercourses (e.g. by establishing buffers or overflows).
Australian consensus guidelines for the safe handling of monoclonal antibodies for cancer treatment by healthcare personnel
Authors: Alexander M. , King J. , Bajel A. , Doecke C. , Fox P. , Lingaratnam S. , Mellor J. D. , Nicholson L. , Roos I. , Saunders T. , Wilkes J. , Zielinski R. , Byrne J. , MacMillan K. , Mollo A. , Kirsa S. , Green M. 
Published: October 2014

AbstractThese consensus guidelines provide recommendations for the safe handling of monoclonal antibodies. Definitive recommendations are given for the minimum safe handling requirements to protect healthcare personnel. The seven recommendations cover: (i) appropriate determinants for evaluating occupational exposure risk; (ii) occupational risk level compared with other hazardous and non‐hazardous drugs; (iii) stratification of risk based on healthcare personnel factors; (iv) waste products; (v) interventions and safeguards; (vi) operational and clinical factors and (vii) handling recommendations. The seventh recommendation includes a risk assessment model and flow chart for institutions to consider and evaluate clinical and operational factors unique to individual healthcare services. These guidelines specifically evaluated monoclonal antibodies used in the Australian cancer clinical practice setting; however, the principles may be applicable to monoclonal antibodies used in non‐cancer settings. The guidelines are only applicable to parenterally administered agents.
Outcome of Surgical and Medical Management of Cecal Impaction in 150 Horses (1991–2011)
Authors: Aitken Maia R. , Southwood Louise L. , Ross Beth M. , Ross Michael W. 
Published: October 2014

ObjectiveTo evaluate short‐ and long‐term outcome after medical and surgical management of horses with cecal impaction and to determine reasons for death or euthanasia.Study DesignRetrospective case series.AnimalsHorses (n = 150).MethodsData collected from medical records (1991–2011) of horses with a diagnosis of cecal impaction, included signalment, history of recent disease/surgical procedure, admission data, management (medical, typhlotomy alone, jejunocolostomy), complications, and outcome. Short‐term outcome (alive or dead at discharge) and long‐term outcome (alive or dead at ≥1 year) were determined by telephone interview. Data were analyzed using a χ2or Fisher's exact test. Level of significance wasP < .05.ResultsOf 150 horses hospitalized with a diagnosis of cecal impaction, 102 (68%) had a history of recent disease or a surgical procedure. Thirty‐eight horses (25%) had cecal perforation at admission and 3 horses (2%) were euthanatized without treatment. Of 109 horses treated, 59 (54%) were managed medically and 50 (46%) surgically (typhlotomy [26]; jejunocolostomy [24]). The proportion of horses alive at hospital discharge was significantly lower for horses managed medically (61%) compared with surgically (82%;P = .02) but there was no difference between horses managed with typhlotomy alone (77%) or with jejunocolostomy (88%;P = .47). There were 57% of horses managed medically alive at 1 year. There was a similar proportion of horses alive at 1 year after typhlotomy alone (73%) and jejunocolostomy (70%;P = .86).ConclusionsCompared to the recent reports, the proportion of horses alive at hospital discharge was lower for both medically and surgically managed horses with cecal impaction. There was decreased survival for horses treated medically than those treated surgically; however, no significant difference was seen in survival between horses managed with typhlotomy alone versus jejunocolostomy.
Surgical Correction of Nephrosplenic Entrapment of the Large Colon in 3 Horses Via Standing Left Flank Laparotomy
Authors: Krueger Clarisa R. , Klohnen Andreas 
Published: October 2014

ObjectiveTo describe a technique for surgical correction of nephrosplenic entrapment via standing left flank laparotomy.Study DesignCase series.AnimalsHorses (n = 3).MethodsNephrosplenic entrapment was diagnosed by abdominal palpation per rectum in all 3 horses and confirmed by transabdominal ultrasonography in 2 horses. Duration of colic was variable and failed to resolve after medical management, phenylephrine administration, and jogging. With sedation and local analgesia, standing left flank laparotomy using a modified grid approach was performed to correct the entrapment. Follow‐up information was obtained by telephone communication with trainers or owners.ResultsNephrosplenic entrapment was successfully corrected in all horses; postoperative fever occurred in 1 horse. Horses were discharged after 48–72 hours and returned to previous use within 30 days.ConclusionStanding flank laparotomy is an alternative for horses with nephrosplenic entrapment unresponsive to medical therapy when general anesthesia and exploratory celiotomy are not an option because of financial constraints or a high anesthetic risk. This approach leads to a favorable outcome, reduces hospital stay and associated costs and leads to a rapid return to function.
Interspecific Differences in Tolerance to Soil Compaction, Drought and Waterlogging Stresses among Maize and Triticale Genotypes
Authors: Grzesiak M. T. , Szczyrek P. , Rut G. , Ostrowska A. , Hura K. , Rzepka A. , Hura T. , Grzesiak S. 
Published: October 2014

AbstractStress susceptibility indexes (SSI) of eight maize and eight triticale genotypes for their ability to cope with soil compaction (SC) combined with drought (D) or waterlogging (W) were estimated through the determination of changes in dry matter of the shoot (S), root (R) and whole plant (S+R) grown at three levels of soil compaction (1.1, 1.3 and 1.6 g cm−3) and exposed to D or W stress for 7 or 14 days. The SSI values showed variation between and within maize and triticale genotypes, and it was possible to divide genotypes into groups of sensitive and resistant ones. The correlation coefficients (r) between stress susceptibility indexes of soil compaction (SCSI) and drought (DSI) or waterlogging (WSI) and between DSI and WSI were statistically significant. This indicates that genotypes resistant to soil compaction (SC) were resistant to drought (D) or waterlogging (W) stresses and that genotypes resistant to D were also resistant to W. Seedlings grown under the stresses showed changes in S to R ratio (S/R). Sensitive genotypes had higher S/R ratio than resistant ones. Decrease of S/R ratio depends on the duration of stresses, and it may be considered an adaptation mechanism to stress. After 7 days of recovery for D and W treatments, we observed only a partial return of growth traits to the level of control plants.
Optimal Management of Riata Leads with No Known Electrical Abnormalities or Externalization: A Decision Analysis
Authors: POKORNEY SEAN D. , ZHOU KE , MATCHAR DAVID B. , LOVE SEAN , ZEITLER EMILY P. , LEWIS ROBERT , PICCINI JONATHAN P. 
Published: October 2014

Riata Decision AnalysisIntroductionRiata and Riata ST implantable cardioverter‐defibrillator (ICD) leads (St. Jude Medical, Sylmar, CA, USA) can develop conductor cable externalization and/or electrical failure. Optimal management of these leads remains unknown.Methods and ResultsA Markov model compared 4 lead management strategies: (1) routine device interrogation for electrical failure, (2) systematic yearly fluoroscopic screening and routine device interrogation, (3) implantation of new ICD lead with capping of the in situ lead, and (4) implantation of new ICD lead with extraction of the in situ lead. The base case was a 64‐year‐old primary prevention ICD patient. Modeling demonstrated average life expectancies as follows: capping with new lead implanted at 134.5 months, extraction with new lead implanted at 134.0 months, fluoroscopy with routine interrogation at 133.9 months, and routine interrogation at 133.5 months. One‐way sensitivity analyses identified capping as the preferred strategy with only one parameter having a threshold value: when risk of nonarrhythmic death associated with lead abandonment is greater than 0.05% per year, lead extraction is preferred over capping. A second‐order Monte Carlo simulation (n = 10,000), as a probabilistic sensitivity analysis, found that lead revision was favored with 100% certainty (extraction 76% and capping 24%).ConclusionsOverall there were minimal differences in survival with monitoring versus active lead management approaches. There is no evidence to support fluoroscopic screening for externalization of Riata or Riata ST leads.
Editorial Perspective: Laying the foundations for next generation models of ADHD neuropsychology
Authors: Sonuga‐Barke Edmund J. S. , Coghill David 
Published: October 2014

The JCPP has just published a virtual issue focusing specifically on the journal's contribution to progress in the field of ADHD neuropsychology over last 30 years and its role in establishing the foundations of next generation ADHD neuropsychology models. The virtual issue is structured around six themes. Here we provide a précis of the issue summarizing these themes and illustrating each with a reference to an influential paper published over the last 5 years.
Non‐ablative fractional photothermolysis in treatment of idiopathic guttate hypomelanosis
Authors: Rerknimitr P. , Chitvanich S. , Pongprutthipan M. , Panchaprateep R. , Asawanonda P. 
Published: October 2014

AbstractBackgroundIdiopathic guttate hypomelanosis (IGH) is a common pigmentary disorder affecting a large number of individuals. Many patients seek medical attention due to aesthetic concern. However, no standard treatment is available.ObjectivesTo evaluate the efficacy and side‐effects of non‐ablative fractional photothermolysis (FP) as a treatment of IGH.Materials and methodsA total of 120 lesions from 30 patients with IGH were treated. In each patient, two lesions on the extremities were assigned to treatment group, while lesions from the other side served as control. The treatment was delivered by fractional 1550‐nm ytterbium/erbium fibre laser for four times at 4‐week intervals. Lesional skin colour was measured by colourimetry. Digital photographs and dermoscopic digital photographs were taken at weeks 0, 4, 8, 12 and 16. In addition, patient satisfaction score and side‐effects were recorded. All clinical photographs were evaluated by three experienced dermatologists to determine clinical improvement using a quartile grading scale.ResultsColourimetry of the treatment side showed normalization of skin colour at each visit and was statistically significant when compared with control after two treatments (week 8) and continued to decrease until 4 weeks' follow‐up (week 16) (P = 0.047, 0.016 and 0.06 respectively). Physicians' improvement grading score showed that 83.34% of the lesions in treatment group vs. 18.34% in the control group showed some improvement. The difference was statistically significant (P < 0.05). Common side‐effects were erythema and oedema in treatment area, which were mild and transient. No post‐inflammatory hyperpigmentation was observed.ConclusionNon‐ablative FP appears to be an effective way to treat IGH. The improvements are documented by both objective and subjective measurements.
Dermoscopic difficult lesions: an objective evaluation of reflectance confocal microscopy impact for accurate diagnosis
Authors: Ferrari B. , Pupelli G. , Farnetani F. , De Carvalho N.T. , Longo C. , Reggiani C. , Argenziano G. , Pellacani G. 
Published: October 2014

AbstractBackgroundEarly detection of melanoma is the main objective to ensure a high survival rate. In some cases melanoma diagnosis still remain difficult and this leads to unnecessary excisions.ObjectiveThe aim of this study was to detect the most relevant Reflectance confocal microscopy (RCM) features for the detection of dermoscopic difficult melanomas.MethodA total of 322 lesions were selected from database and were evaluated on dermoscopy according to the 7‐point checklist score, in blind from histological diagnosis. We classified the lesions into three categories: (i) ‘featureless’ lesions with score ranging between 0 and 2; (ii) ‘positive‐borderline’ moles with score between 3 and 4 and (iii) ‘positive‐clear cut’ lesions with score from 5 to 10. We evaluated confocal features of the ‘featureless’ lesions and of the ‘positive‐borderline’ lesions. Evaluated confocal features were as follows: presence of pagetoid cells, cell shape (roundish or dendritic) and number (< 5 or >5 cells per mm2), overall architecture (ringed, meshwork, clods and non‐specific pattern); architectural disorder, presence of cytological atypia (>5 cells per mm2) and cells arranged in nests.ResultsAmong 322 lesions 70 were melanomas and 252 were nevi. According to the classification based on the 7‐point checklist score, 130 ‘featureless lesions’ (score 0–2) including six melanomas, and 102 ‘positive‐borderline’ moles (score 3–4) including 17 melanomas, were identified. Round pagetoid cells >5 cells per mm2 and/or architectural disorder on RCM were found in all of six melanomas with featureless dermoscopy. Round pagetoid infiltration and five or more atypical cells at the DEJ were found in 16 positive ‘borderline melanomas’.ConclusionsRCM represents a rapid non‐invasive technique that can aid early diagnosis of dermoscopic difficult melanomas. Use of RCM on lesions with clinical and/or dermoscopic suspect of malignancy may reduce the number of unnecessary excision increasing the rate of accurate diagnoses.
Genetic variant in 8q24 is associated with prognosis for gastric cancer in a Chinese population
Authors: Ma Gaoxiang , Gu Dongying , Lv Chunye , Chu Haiyan , Xu Zhi , Tong Na , Wang Meilin , Tang Cuiju , Xu Yong , Zhang Zhengdong , Wang Baolin , Chen Jinfei 
Published: October 2014

AbstractBackground and AimSingle nucleotide polymorphisms (SNPs) located in long noncoding RNA CASC8 gene may influence the process of splicing and stability of messenger RNA conformation, resulting in the modification of its interacting partners. Genome‐wide association studies have identified the SNP rs10505477 and SNP rs1562430 in CASC8 were associated with risk of the colorectal cancer (CRC) and breast cancer, respectively.MethodsIn the present study, we genotyped the 940 surgically resected gastric cancer patients to explore the association between these two SNPs (e.g. rs10505477 and rs1562430) and survival of gastric cancer in a Chinese population.ResultsWe found that the patients carrying rs10505477 GG genotype survived for a longer time than those with the GA and AA genotypes (log‐rank P = 0.030). The similar result was also found in the dominant model (GA/AA vs GG, HR = 1.32, 95% CI = 1.08–1.63, log‐rank P = 0.008). This risk effect was more pronounced among patients with tumor size ≤ 5 cm, diffuse‐type gastric cancer, lymph node metastasis, no distant metastasis, and TNM stage III and IV. Furthermore, the area under the curve at five years was dramatically increased from 0.619 to 0.624 after adding the rs10505477 risk score to the traditional clinical risk score (TNM stage and lymph node metastasis). However, there was no association be found between the rs1562430 and the survival of gastric cancer.ConclusionThese findings suggested the SNP rs10505477 may contribute to the survival of gastric cancer and be a potential prognostic biomarker of gastric cancer.
Agreement between student dietitians' identification of refeeding syndrome risk with refeeding guidelines, electrolytes and other dietitians: a pilot study
Authors: Matthews K. , Owers E. , Palmer M. 
Published: October 2014

AbstractBackgroundLimited research exists concerning how consistently and accurately student and newly‐graduated dietitians are identifying refeeding syndrome risk in hospitalised patients. The present study aimed to determine the consistency of students' and newly‐graduated dietitians' classification of refeeding syndrome risk, as well as agreement with the application of comparison tools such as the National Institute for Health and Care Excellence guidelines, patients' electrolytes and supplementation, and clinical dietitians previously surveyed.MethodsRecently‐graduated and final‐year Griffith University dietetics students were invited to complete an online survey. The survey questioned demographics and asked respondents to classify the level of refeeding syndrome risk (i.e. none, some, high, unsure) in 13 case studies. Electrolytes and supplementation data were sourced from electronic patient records. Chi‐squared tests, t‐tests and linear regression analyses were conducted.ResultsFifty‐three eligible people responded [n = 53 of 112, mean (SD) age 26 (4) years, 89% female, 34% graduates]. Respondents' answers were generally more consistent and more likely to agree with comparison tools when two tools showed the same level of refeeding syndrome risk (49–98%, β = 0.626–1.0994, P < 0.001) than when they differed (11–49%). Respondents' level of agreement with refeeding identification guidelines, electrolyte levels, supplementation and dietitians previously surveyed did not differ by graduate status, degree level, clinical placement status or having read refeeding syndrome guidelines recently (P > 0.05).ConclusionsStudents' and new graduates' identification of refeeding syndrome risk improved when there was consistency between guidelines, electrolytes and dietitians' responses. More research is needed to improve the evidence behind refeeding guidelines, with the aim of enhancing the accuracy and consistency of assessment.
Development of a partnership causal model for couples undergoing fertility treatment
Authors: Asazawa Kyoko , Mori Akiko 
Published: October 2014

AbstractAimThe goals of this study were to develop a partnership causal model and verify the model's fitness for couples undergoing fertility treatment.MethodsA purposive sample of 1004 consenting participants (502 couples) undergoing fertility treatment was selected from five fertility clinics across Japan. A mailed self‐administered questionnaire was used to collect data. The partnership causal model was examined with structural equation modeling.ResultsA total of 565 questionnaires were returned (56.3%) and the number of valid responses was 466 (46.4%). The factor “medical professionals' support (nurses and physicians)” influenced the couples' “partnership” (β = 0.16) and had a direct effect on the men's quality of life (QOL) and an indirect effect on the women's QOL (β = 0.20). Couples' partnership had a significant impact on couples' QOL (β = 0.20) and on “satisfaction in their relationship with their partner” (β = 0.48). The multi‐population path analysis revealed that married couples influenced each other's perceptions of their partnership (men, β = 0.84; women, β = 0.88). Additionally, the spouse's partnership influenced both individual's QOL (men, β = 0.77; women, β = 0.77) and the satisfaction with the relationship (men, β = 0.46; women, β = 0.59). The participants' “distress” significantly and negatively affected the participants' QOL.ConclusionThe results revealed that for a couple undergoing fertility treatments, a strong partnership maintains their QOL, and this could decrease the couples' distress (particularly in women). Partnership was also related to the variability of “medical professionals' support”.
Cervix assessment for the management of labor induction: Reliability of cervical length and Bishop score determined by residents
Authors: Garcia‐Simon Raquel , Oros Daniel , Gracia‐Cólera Daniel , Moreno Esther , Paules Cristina , Cañizares Silvia , Gascón Elena , Fabre Ernesto 
Published: October 2014

AbstractAimTo evaluate the reliability of two techniques of cervical ripeness assessment at the beginning of labor induction, as assessed by inexperienced observers.MethodsA total of 120 women were prospectively studied at admission for labor induction. Two independent physicians examined consenting women successively but separately. One experienced consultant and one of the six first‐year obstetrics residents composed the pairs of observers. The trainees had very limited prior experience with cervical ultrasound scan or evaluating Bishop score. Cervical length and Bishop score were evaluated according to standard methodology. Reliability was described by intraclass correlation coefficients (ICC) and coefficients of variation (COV). Ultrasound cervical length was plotted according to the Bland–Altman method.ResultsThe median Bishop score and mean cervical length were similar for all observers. Ultrasound cervical length and Bishop score were highly reliable when evaluated by first‐year residents. Ultrasound cervical length showed the highest interobserver agreement, with ICC values over 0.9 and COV values of approximately 10% or less for all trainees. The Bishop score was also reliable, but with lower ICC and higher COV values.ConclusionBishop score and ultrasound cervical length examination for the management of labor induction are accurate and easy to learn by inexperienced first‐year residents. However, cervical length showed higher reliability than the Bishop score.
Autoimmune lymphoproliferative syndrome in pregnancy: A case of favorable mother–fetal outcome in a well‐controlled disease
Authors: Patti Simona , Perrone Giuseppina , De Pratti Valentina , Quinti Isabella , Milito Cinzia , Brunelli Roberto 
Published: October 2014

AbstractThe autoimmune lymphoproliferative syndrome (ALPS) is a disorder of abnormal lymphocyte survival caused by the dysregulation of the Fas apoptotic pathway. The Fas gene is expressed at the maternal–fetal interface and is involved in the regulation of immune response and implantation. Altered Fas expression may result in altered apoptosis and, ultimately, affect both the immune response and implantation; it is in fact associated with recurrent pregnancy loss, preterm premature rupture of membranes and pre‐eclampsia. Currently, there are over 500 cases of ALPS reported worldwide from various racial and ethnic backgrounds. Up to date, the published work contains no specific reports on pregnancy outcome in women affected by ALPS. We present a case of full‐term uneventful pregnancy in a patient affected by ALPS. A specific clinical follow‐up in a pregnant woman with primary immunologic disease is suggested.