bluuebunny/crossref_metadata_2025_split huggingface dataset:
Child temperament and trajectories of student–teacher relationships quality
Authors: Harvey Elizabeth , Déry Michèle , Lemelin Jean‐Pascal , Bégin Vincent 
Published: August 2024

AbstractThis study aimed to examine the associations between child temperament and trajectories of the three dimensions of the student–teacher relationship (Closeness, Conflict, and Dependency) during elementary school. Latent class growth analyses conducted among 744 French‐Canadian students recruited between 2008 and 2010 (46.8% girls; M
age = 8.39; 90.9% White; 49.7% with externalizing behavior problems) revealed four Closeness trajectories and three Conflict trajectories, but no significant variability between children in mean levels of change in Dependency. Surgency‐Extraversion and Effortful control were associated with specific trajectories of Closeness and Conflict. Effortful control was also associated with cross‐sectional assessments of Dependency. These results suggest that temperament is a useful construct in understanding developmental patterns of the student–teacher relationship across the elementary school years.
A family systems investigation on couple emotional intimacy, parent–child relationships, and child social skills in middle childhood
Authors: Wu Qiong , Han Soojin , Tawfiq Dania , Jalapa Karina , Lee Chorong , Pocchio Kinsey 
Published: August 2024

AbstractThis study investigated familial attachment‐based processes in middle childhood, using 788 families (50.6% boys; 84.4% White), assessed six times from 4.5 years old to Grade 6. An adapted Random Intercept Cross‐Lagged Panel Model revealed between‐family associations among couple emotional intimacy, relationships with both parents, and child social skills (β = .18–.66). Within‐family increases in child assertion and self‐control prospectively predicted relationships with parents (βs = .13), and parent–child relationships predicted various child social skills (βs = .13–.17). Couple emotional intimacy predicted child cooperation, assertion, and responsibility (βs = .12–.24) and father–child relationships in Grade 6 (βs = .20–22) at the within‐family level. Findings underscore a systemic consideration of attachment‐based processes in the family.
Evolving Trends and Impact of Waitlist Transfusion on Recipient Outcomes Following Heart Transplantation
Authors: Hong Yeahwa , Iyanna Nidhi , Hess Nicholas R. , Ziegler Luke A. , Abdullah Mohamed , Dorken‐Gallastegi Ander , Mathier Michael A. , Keebler Mary E. , Hickey Gavin W. , Kaczorowski David J. 
Published: August 2024

ABSTRACTBackgroundThis study evaluates the clinical trends, risk factors, and impact of waitlist blood transfusion on outcomes following isolated heart transplantation.MethodsThe UNOS registry was queried to identify adult recipients from January 1, 2014, to June 30, 2022. The recipients were stratified into two groups depending on whether they received a blood transfusion while on the waitlist. The incidence of waitlist transfusion was compared before and after the 2018 allocation policy change. The primary outcome was survival. Propensity score‐matching was performed. Multivariable logistic regression was performed to identify predictors of waitlist transfusion. A sub‐analysis was performed to evaluate the impact of waitlist time on waitlist transfusion.ResultsFrom the 21 926 recipients analyzed in this study, 4201 (19.2%) received waitlist transfusion. The incidence of waitlist transfusion was lower following the allocation policy change (14.3% vs. 23.7%, p < 0.001). The recipients with waitlist transfusion had significantly reduced 1‐year posttransplant survival (88.8% vs. 91.9%, p < 0.001) compared to the recipients without waitlist transfusion in an unmatched comparison. However, in a propensity score‐matched comparison, the two groups had similar 1‐year survival (90.0% vs. 90.4%, p = 0.656). Multivariable analysis identified ECMO, Impella, and pretransplant dialysis as strong predictors of waitlist transfusion. In a sub‐analysis, the odds of waitlist transfusion increased nonlinearly with longer waitlist time.ConclusionThere is a lower incidence of waitlist transfusion among transplant recipients under the 2018 allocation system. Waitlist transfusion is not an independent predictor of adverse posttransplant outcomes but rather a marker of the patient's clinical condition. ECMO, Impella, and pretransplant dialysis are strong predictors of waitlist transfusion.
Comparison of the modified Masood's scoring index versus international academy of cytology Yokohama system in the categorization of breast fine needle aspirates
Authors: Khan Adil Aziz , Ahuja Sana , V Shakthivel , Zaheer Sufian , Ranga Sunil 
Published: August 2024

AbstractContextThe Modified Masood Scoring Index (MMSI) categorizes breast fine needle aspirates into four categories non‐proliferative breast diseases (PBD), PBD without atypia, PBD with atypia and carcinoma in situ/carcinoma. The International Academy of Cytology Yokohama System classifies the aspirates into five categories – inadequate, benign, atypical, suspicious, and malignant. Very few studies have been conducted so far to compare the diagnostic accuracy of this system.AimsThe objectives of the study were to classify breast fine needle aspirates according to the MMSI and IAC Yokohama and assess their risk of malignancy (ROM) and performance parameters.Materials and MethodsAll breast FNAs received from June 2020 to May 2023 were classified according to the MMSI and IAC Yokohama. Using histopathological diagnosis as the gold standard, ROM and performance parameters were calculated.ResultsOut of the 559 breast fine needle aspirates, the histopathological correlation was available for 337 cases. The ROM for non‐PBD, PBD without atypia, PBD with atypia and carcinoma in situ/carcinoma categories were 0%, 1.2%, 9.1% and 93%, respectively. The ROM for each of the categories of Yokohama system was 16.6%, 1.1%, 4.3%, 86.2% and 97.6%, respectively. The values for the sensitivity, specificity, PPV, NPV and diagnostic accuracy were slightly higher for IAC Yokohama (97.3%, 97.2%, 94.7%, 98.6% and 97.2%, respectively) than the MMSI (96.4%, 96.2%, 93%, 98.1% and 96.3%, respectively). Furthermore, another shortfall of MMSI is the inability to compare the Inadequate category of the Yokohama system.ConclusionOverall Yokohama system proved to be a better system for categorizing breast lesions on FNAB as the scoring system provides more objective categorization and minimizes false positive and false negative cases.
The Contrasting Footprint of Labour and Capital in Post‐colonial India
Authors: Breman Jan 
Published: August 2024

ABSTRACTIndia's struggle for independence held the promise of an end to poverty and redemption from the communal‐cum‐class‐based inequality which had kept the peasant economy backward. But the planned substitution of the agrarian‐rural fabric for an industrial‐urban way of life failed to materialize. Casualization and contractualization of waged work indicated that labour had become thoroughly commodified in a state of ongoing footlooseness. It was a proletarianization which did not allow for the collective action precondition to raise and settle the social question. The onslaught of neoliberal capitalism in the last quarter of the 20th century ended the brokerage of the nation state to secure the interests of labour next to those of capital. Less than 10 per cent of the workforce has continued to enjoy formalized occupational engagement, mainly in the downgraded public economy. Corporate capital in collusion with statist autocracy has not only effectuated the deregulation of employment but also abandoned the legal code of formality. The outcome is a state of lawlessness for the people at the bottom of the pile. Besides big business, politics and governance are identified in this reconfiguration as stakeholders in a brutal regime of informality, erosive of equality, democracy, welfare and civil rights.
Feasibility of caregiver diabetes distress screening in routine clinical care of youth with type 1 diabetes
Authors: Alkhatib Einas H. , Clary Lauren , Eddington Angelica , Streisand Randi , Majidi Shideh 
Published: August 2024

AbstractAimsCaregiver diabetes distress (DD) consists of feeling overwhelmed, sad, and/or concerned; one‐third of parents of youth with type 1 diabetes (T1D) report severe distress up to 4 years after T1D diagnosis. PAID‐PR (Problem Areas in Diabetes Survey—Parent Revised) assesses DD primarily in research settings; however, less is known about its clinical utility. We aimed to identify the feasibility of implementing PAID‐PR screening at a diverse, academic US paediatric diabetes center during routine clinic follow‐up visits through quality improvement methodologies.MethodsThe PAID‐PR was intended to be offered in English to caregivers at all paediatric T1D appointments, by the front desk during appointment check‐in, or through REDCap prior to telehealth appointments or at local sites to all eligible caregivers. Adult psychosocial resources were provided to all, regardless of score. Forms were scored after appointments; scores ≥80 were referred to Diabetes Psychology providers for follow‐up.ResultsA total of 391 caregivers completed the PAID‐PR, though only half of eligible caregivers received it in person. Response rates were highest in person (90%), compared to REDCap (25%). In total, 27% (n = 107) scored ≥56 (DD). Of those with DD, 21% (n = 23) scored ≥80 and were referred to psychology. Demographics are reported in Table 1. PAID‐PR score was positively correlated to A1c (p = 0.038) and inversely to child age (p = 0.014).ConclusionClinic caregiver DD screening was implemented with higher response rates in person; however, expanding in‐person screening to all eligible caregivers is necessary. Furthermore, since the PAID‐PR was in English, some caregivers with DD were likely missed. Future directions include screening in additional languages.
Metabolically healthy obesity and left ventricular geometric remodelling in Chinese children
Authors: Yang Lili , Li Menglong , Wang Huan , Shu Wen , Zhao Min , Magnussen Costan G. , Hu Yifei , Xi Bo 
Published: August 2024

AbstractAimTo investigate the association between metabolically healthy obesity (MHO) and left ventricular geometric remodelling in Chinese children.Materials and MethodsThis cross‐sectional study used data from two population‐based samples in China, including 2871 children aged 6–11 years. Weight status was defined based on body mass index according to the World Health Organization growth chart. Metabolic status was defined based on the 2018 consensus‐based criteria proposed by Damanhoury et al. Obes Rev 2018;19:1476–1491 (blood pressure, lipids and glucose). Left ventricular geometric remodelling was determined as concentric remodelling, eccentric hypertrophy, and concentric hypertrophy. Multinomial logistic regression analysis was used to determine odds ratios (ORs) and 95% confidence intervals (CIs) for the association between categories of weight and metabolic status and left ventricular geometric remodelling.ResultsCompared with children with metabolically healthy normal weight, those with MHO had higher odds of left ventricular geometric remodelling, with adjusted ORs (95% CIs) of 2.01 (1.23–3.28) for concentric remodelling, 6.36 (4.03–10.04) for eccentric hypertrophy, and 17.07 (7.97–36.58) for concentric hypertrophy. Corresponding ORs (95% CIs) were 2.35 (1.47–3.75), 10.85 (7.11–16.55), and 18.56 (8.63–39.94), respectively, for children with metabolically unhealthy obesity. In contrast, metabolically unhealthy normal weight was not associated with higher odds of left ventricular geometric remodelling. Findings were consistent in sensitivity analyses that used different definitions of weight and metabolic status and left ventricular geometric remodelling.ConclusionsChildren with MHO had higher odds of left ventricular geometric remodelling than their metabolically healthy normal weight counterparts. Our findings suggest MHO may not be a benign condition for cardiac health in children.
Evolution from an antecedent chronic myeloid malignancy does not impact survival outcomes in NPM1‐mutated AML
Authors: Smith Elliot , Atenafu Eshetu G. , Bankar Aniket , Chan Steven , Davidson Marta , Gupta Vikas , Minden Mark D. , Richard‐Carpentier Guillaume , Schimmer Aaron , Schuh Andre C. , Sibai Hassan , Yee Karen , Maze Dawn 
Published: August 2024

AbstractNucleophosmin‐1 (NPM1)‐mutated AML is a molecularly defined subtype typically associated with favorable treatment response and prognosis; however, its prognostic significance in AML evolving from an antecedent chronic myeloid malignancy is unknown. This study's primary objective was to determine the impact of mutated NPM1 on the prognosis of AML evolving from an antecedent chronic myeloid malignancy. We conducted a retrospective chart review including patients with NPM1‐mutated de novo and sAML. sAML was defined as those with a preceding chronic‐phase myeloid malignancy before diagnosis of AML. Of 575 NPM1‐mutated patients eligible for inclusion in our study, 51 (8.9%) patients were considered to have sAML. The median time from diagnosis of NPM1‐mutated chronic myeloid malignancy to sAML evolution was 3.6 months (0.5–79.3 months). No significant differences in leukemia‐free (2‐year LKFS 52.0% vs. 51.2%, p = .9922) or overall survival (2‐year OS 56.3% vs. 49.4%, p = .4246) were observed between patients with NPM1‐mutated de novo versus sAML. Our study suggests that evolution from a preceding myeloid malignancy is not a significant predictor of poor prognosis in the setting of an NPM1 mutation. Our study demonstrated a short time to progression to sAML in most patients, which further supports the consideration of NPM1 as an AML‐defining mutation.
Land use and soil property effects on aggregate stability assessed by three different slaking methods
Authors: Poeplau Christopher , Riefling Thaddäus , Schiedung Marcus , Anlauf Rüdiger 
Published: August 2024

AbstractAggregate stability is an important structural feature of soils, since it controls surface erosion, water infiltration, plant growth and carbon stabilisation. As such, it might be considered as a potential descriptor of soil health in repeated national to continental‐scale soil monitoring programmes, which is, as of now, rarely the case. This might be related to (i) the conception that it can be predicted reasonably well by standard soil parameters, and (ii) the lack of a high‐throughput method. Here, we used a paired plot approach with 50 cropland and adjacent grassland field margin plots to specifically test (i) if measuring aggregate stability is added value over its mere estimation based on soil properties, and (ii) if a high throughput image recognition method can bear comparison with more classical methods. We evaluated the mean weight diameter (MWD), water stable aggregates (WSA) using classical setups, as well as the slaking index (SI) via imagine recognition. Methods were compared regarding their sensitivity to considered parameters as well as their reproducibility. Soil organic carbon (SOC) as well as aggregate stability were significantly higher under grassland than under cropland soils. Remarkably, the specific design of the study could reveal that the difference in aggregate stability between land use types was not solely affected by SOC content and quality, derived from mid‐infrared spectroscopy. Quality and spatial distribution of organic matter inputs, absence of disturbance, as well as biotic parameters might all be relevant factors. Nevertheless, an important finding was that SOC quality had a higher explanatory power than SOC content alone for two out of three methods. Overall, the MWD was the most sensitive to the assessed drivers and together with the WSA the most reproducible method, with coefficients of variation below 6%. By contrast, those of the SI were as high as 192%, which hampered the detection of clear patterns along the soil property gradient and between land use types. For high‐quality scientific applications, 2D image recognition cannot be recommended. Instead, we recommend the use of the MWD or WSA method for scientific purposes with a low number of technical replicates in larger‐scale assessments to further unravel the importance of aggregate stability for healthy soils, and to better determine the underlying factors.
Pro‐inflammatory activity of Cutibacterium acnes phylotype IA1 and extracellular vesicles: An in vitro study
Authors: Cheung Caroline T. , Lancien Ugo , Corvec Stéphane , Mengeaud Valérie , Mias Céline , Véziers Joëlle , Khammari Amir , Dréno Brigitte 
Published: August 2024

AbstractAcne is a chronic inflammatory skin condition that involves Cutibacterium acnes (C. acnes), which is classified into six main phylotypes (IA1, IA2, IB, IC, II and III). Acne development is associated with loss of C. acnes phylotype diversity, characterised by overgrowth of phylotype IA1 relative to other phylotypes. It was also shown that purified extracellular vesicles (EVs) secreted by C. acnes can induce an acne‐like inflammatory response in skin models. We aimed to determine if the inflammatory profile of EVs secreted by C. acnes phylotype IA1 from an inflammatory acne lesion was different from C. acnes phylotype IA1 from normal skin, thus playing a direct role in the severity of inflammation. EVs were produced in vitro after culture of two clinical strains of C. acnes phylotype IA1, T5 from normal human skin and A47 from an inflammatory acne lesion, and then incubated with either human immortalised keratinocytes, HaCaT cells, or skin explants obtained from abdominoplasty. Subsequently, quantitative PCR (qPCR) was performed for human β‐defensin 2 (hBD2), cathelicidin (LL‐37), interleukin (IL)‐1β, IL‐6, IL‐8, IL‐17α and IL‐36γ, and ELISA for IL‐6, IL‐8 and IL‐17α. We found that EVs produced in vitro by C. acnes derived from inflammatory acne lesions significantly increased the pro‐inflammatory cytokines and anti‐microbial peptides at both transcriptional and protein levels compared with EVs derived from normal human skin. We show for the first time that C. acnes EVs from inflammatory acne play a crucial role in acne‐associated inflammation in vitro and that C. acnes phylotype IA1 collected from inflammatory acne lesion and normal skin produce different EVs and inflammatory profiles in vitro.
An overview of S100 proteins and their functions in skin homeostasis, interface dermatitis conditions and other skin pathologies
Authors: Abdi Warda , Romasco Andrew , Alkurdi Dany , Santacruz Elise , Okinedo Isabel , Zhang Yuying , Kannan Shriya , Shakiba Saeed , Richmond Jillian M. 
Published: August 2024

AbstractS100 proteins comprise a family of structurally related proteins that are calcium‐sensitive. S100 proteins have been found to play various roles in regulation of cell apoptosis, cell proliferation and differentiation, cell migration and invasion, energy metabolism, calcium homeostasis, protein phosphorylation, anti‐microbial activity and inflammation in a variety of cell types. While the specific function of many S100 proteins remains unknown, some of the S100 proteins serve as disease biomarkers as well as possible therapeutic targets in skin diseases. Interface dermatitis (ID) is a histopathological term that covers many different skin conditions including cutaneous lupus erythematosus, lichen planus, and dermatomyositis. These pathologies share similar histological features, which include basal cell vacuolization and lymphocytic infiltration at the dermal‐epidermal junction. In this review, we summarize how the S100 protein family contributes to both homeostatic and inflammatory processes in the skin. We also highlight the role of S100 proteins in neuronal signalling, describing how this might contribute to neuroimmune interactions in ID and other skin pathologies. Last, we discuss what is known about the S100 family proteins as both biomarkers and potential treatment targets in specific pathologies.
Characteristics of juvenile chum salmon carrying out inverse migrations after ocean entry from rivers along the Pacific coast of Hokkaido, Japan
Authors: Honda Kentaro , Shirai Kotaro , Morishita Takumi , Saito Toshihiko 
Published: August 2024

AbstractAfter ocean entry, juvenile Japanese chum salmon migrate northeastward to the Sea of Okhotsk. However, some juveniles originating in rivers along the Pacific coast of Hokkaido were reported to migrate in the opposite direction (westward). We compiled historical data to determine which river‐origin juveniles migrate westward and to what extent. Then, the ocean‐entry conditions and growth rates of 398 juveniles from two rivers along the Pacific coast of Hokkaido were estimated with otolith daily‐increment analysis. Many juveniles migrated >100 km westward from multiple natal river mouths. Juveniles collected to the west of their natal rivers tended to enter the ocean earlier than those collected to the east, and many did so before sea surface temperatures reached 5°C (the lower limit of the empirically favorable temperature range). In the west, many small juveniles were collected soon after ocean entry, suggesting that they migrated passively with the Coastal Oyashio, a westward cold current. By contrast, juveniles collected in the east tended to grow faster in length and have a lower body condition factor at capture, possibly due to growth‐dependent mortality during their migration against the flow of the Coastal Oyashio. Moreover, many juveniles in the west were exposed to temperatures near 13°C (the upper limit of favorable temperatures) at capture. In recent years, there has been a shortening of the favorable water‐temperature period and a drastic decline in adult chum returns in the region. There is hence concern that the likelihood of abortive migrations for juveniles transported westward will increase.
Multimorbidity and risk of falls, fractures, and joint replacements over two decades: Findings from the Hertfordshire Cohort Study
Authors: Westbury Leo D , Pearse Camille , Rambukwella Roshan , Ward Kate A , Cooper Cyrus , Dennison Elaine M 
Published: August 2024

AimTo examine the relationship between level of morbidity burden and long‐term risk of fractures, falls, and joint replacements in the community‐dwelling participants of the Hertfordshire Cohort Study.MethodsData were analyzed from 2997 individuals (age 59–73 at baseline). Outcomes (fractures, falls, and lower limb joint replacements) were identified using ICD‐10 and OPCS‐4 codes from Hospital Episode Statistics data, available from baseline (1998–2004) until December 2018. Number of systems medicated (marker of morbidity level) in relation to risk of outcomes was examined using sex‐stratified Cox regression.ResultsAmong both men and women, a greater number of systems medicated was related to increased risk of falls (P < 0.001) and lower limb joint replacements (P < 0.003). More systems medicated was only related to increased risk of fracture among women (P‐values for trend of <0.001 among women and 0.186 among men).ConclusionsHigher morbidity was associated with increased risk of adverse health outcomes related to poor musculoskeletal health, but these relationships varied according to the musculoskeletal outcome studied. Intervention strategies to reduce multimorbidity among middle‐aged and older people may hence reduce the burden of musculoskeletal aging. Geriatr Gerontol Int 2024; 24: 912–917.