bluuebunny/crossref_metadata_2025_split huggingface dataset:
COMMUNICATION RELATIONSHIP OF HEALTH WORKERS TOWARDS THE IMPLEMENTATION OF BASIC IMMUNIZATION IN THE WORKING AREA OF BLANG KUTA HEALTH CENTER, BANDAR DUA DISTRICT, PIDIE JAYA REGENCY
Authors: Munawir Munawir , Ichwansyah Fahmi , Azwar Eddy 
Published: June 2024

Background: Basic immunization coverage in Pidie Jaya Regency from January to December was 29.6% for measles immunization. One of the health centers with the lowest basic immunization is Blang Kuta at 12.9%. This research aims to determine the relationship between health worker communication and the implementation of basic immunization in the work area of the Blang Kuta Health Center. Methods: This research is descriptive- analytic with a cross-sectional design. The population in this study was 145 mothers who had babies aged 0-12 years in the Blang Kuta Community Health Center working area. The sample, consisted of 60 respondents who were determined using the Proportional Random Sampling technique. Data analysis used the Chi-Square test with SPSS. Results: Based on univariate analysis shows that the implementation of basic immunization in the Kuta Blang Health Center working area is still low (61.7%), there is a lack of information sources (71.7%), there is a lack of media (76.7%), there is a lack of communication messages (73.3%), lack of recipients of information (58.3%). Based on bivariate analysis, there is a relationship between information sources (p value=0.012), communication messages (p value=0.043), and recipients of information (p value=0.015) on the implementation of basic immunization in the Blang Kuta Community Health Center Working Area in 2019. Recommendation: Health workers should improve their effective communication skills, so they can provide good and clear information about immunization procedures to the public, especially mothers who have babies and toddlers.
TESS Hunt for Young and Maturing Exoplanets (THYME). X. A Two-planet System in the 210 Myr MELANGE-5 Association
Authors: Thao Pa Chia , Mann Andrew W. , Barber Madyson G. , Kraus Adam L. , Tofflemire Benjamin M. , Bush Jonathan L. , Wood Mackenna L. , Collins Karen A. , Vanderburg Andrew , Quinn Samuel N. , Zhou George , Newton Elisabeth R. , Ziegler Carl , Law Nicholas , Barkaoui Khalid , Pozuelos Francisco J. , Timmermans Mathilde , Gillon Michaël , Jehin Emmanuël , Schwarz Richard P. , Gan Tianjun , Shporer Avi , Horne Keith , Sefako Ramotholo , Suarez Olga , Mekarnia Djamel , Guillot Tristan , Abe Lyu , Triaud Amaury H. M. J. , Radford Don J. , Lopez Murillo Ana Isabel , Ricker George R. , Winn Joshua N. , Jenkins Jon M. , Bouma Luke G. , Fausnaugh Michael , Guerrero Natalia M. , Kunimoto Michelle 
Published: June 2024

Abstract
Young (<500 Myr) planets are critical to studying how planets form and evolve. Among these young planetary systems, multiplanet configurations are particularly useful, as they provide a means to control for variables within a system. Here, we report the discovery and characterization of a young planetary system, TOI-1224. We show that the planet host resides within a young population we denote as MELANGE-5. By employing a range of age-dating methods—isochrone fitting, lithium abundance analysis, gyrochronology, and Gaia excess variability—we estimate the age of MELANGE-5 to be 210 ± 27 Myr. MELANGE-5 is situated in close proximity to previously identified younger (80–110 Myr) associations, Crius 221 and Theia 424/Volans-Carina, motivating further work to map out the group boundaries. In addition to a planet candidate detected by the TESS pipeline and alerted as a TESS object of interest, TOI-1224 b, we identify a second planet, TOI-1224 c, using custom search tools optimized for young stars (Notch and LOCoR). We find that the planets are 2.10 ± 0.09 R
⊕ and 2.88 ± 0.10 R
⊕ and orbit their host star every 4.18 and 17.95 days, respectively. With their bright (K = 9.1 mag), small (R
* = 0.44 R
⊙), and cool (T
eff = 3326 K) host star, these planets represent excellent candidates for atmospheric characterization with JWST.
Enseigner les humanités numériques en Tunisie : conditions, pratiques et choix
Authors: Cavallo Delphine , Chebbi Aïda 
Published: June 2024

L’enseignement des humanités numériques à l’Université tunisienne, présent mais peu structuré, n’a pas encore fait l’objet de recherches ni d’analyses didactiques. Cet article propose, sous forme de retours de différentes expériences des autrices, d’explorer la manière dont se déploient ces enseignements dans un espace académique national, à la fois inséré dans des échanges internationaux et présentant des caractéristiques propres. Il s’agit, à la lumière de la littérature existante sur le sujet, de souligner les adaptations des pratiques pédagogiques caractéristiques des humanités numériques à la situation tunisienne. Notre focus porte sur les conditions de faisabilité d’un tel enseignement en Tunisie, à tout le moins en direction des étudiantes et étudiants tunisiens, en montrant comment nos expériences ont nourri notre réflexion pour la conception d’un cours d’introduction aux humanités numériques en ligne dans le cadre du projet Erasmus + Raqmyat. Nous en concluons que l’analyse des pratiques pédagogiques en situation réelle doit faire partie de l’éthique de l’enseignement des humanités numériques.
Huge Left Atrium Thrombus Presenting with Syncope and Sudden Death, Diagnosed by Point-of-care Ultrasound
Authors: Chiu Yu-Cheng , Chen Jiann-Hwa , Chen Wei-Lung , Chung Jui-Yuan 
Published: June 2024

Abstract
The left atrium (LA) thrombus is a life-threatening disease that can result in systemic embolization and sudden death if misdiagnosed. Point-of-care ultrasound (POCUS) is an efficient tool able to assist emergency physicians in accurately and promptly identifying patients with LA thrombus. We present a 72-year-old man who presented at the emergency department with out-of-hospital cardiac arrest. The patient received cardiopulmonary resuscitation and achieved spontaneous circulation upon arrival. The patient had a past history of mitral valve regurgitation and valve replacement, followed by warfarin treatment for 5 years. Clinical examination, including POCUS, resulted in a diagnosis of LA thrombus with systemic thromboembolism events affecting the brain, kidney, and lower limbs. Although an emergency thrombectomy was performed immediately, the patient eventually died. POCUS should be performed in patients with any prior history of structural heart disease, especially those who received valve replacement surgery, to identify life-threatening thromboembolism events and facilitate prompt treatment.
Histological and Immunohistological Findings in Vesicoureteric and Pelviureteric Junction Obstructions; a Spectrum of the Same Mishap – An Observational Study
Authors: Patil Priya Santosh , Patil Santosh Vasantrao , Dhobale Manisha Randhir , Mudiraj Nitin Radhakishan 
Published: June 2024

Background:
Vesicoureteric and pelviureteric junction obstructions (VUJOs and PUJOs) are the most common causes of congenital obstructions of the urinary tract, and yet the pathophysiology of these conditions is unclear. This study aimed to compare the histological findings of age-matched VUJO and PUJO cases for wall thickness, fibrosis, and the presence of interstitial cells of Cajal (ICC).

Methodology:
This was an observational, inter-institutional study done in the period between January 2020 and May 2021. Twelve age-matched cases of VUJO and PUJO were studied to compare histological findings when stained with hematoxylin and eosin, Masson trichrome, and immunohistochemical stains.

Results:
Results showed that the thickness of the muscle layer was increased in both VUJO and PUJO with no statistically significant difference. Perifascicular fibrosis was significantly more in VUJO as compared to PUJO. ICCs were less than grade 3 in most cases of VUJO and PUJO.

Conclusions:
The histological findings of VUJO and PUJO showed similarities, with more fibrosis in VUJO. The density of ICCs was less in both upper and lower urinary obstructions. As both conditions are the result of the same mishap – failure of maturation of fetal ureters, there may be a possibility that patients of PUJO can also have VUJO.
Retrospective Evaluation of the Effects of Local Anesthesia Before Tooth Extraction Procedures under General Anesthesia on Physiologic Parameters and Postoperative Bleeding in Children
Authors: Turan Y , Senirkentli GB , Cekmen N , Tirali E , Çakmak E 
Published: June 2024

Background:
Studies have been conducted to evaluate changes in hemodynamics, postoperative bleeding, and pain in pediatric dental patients receiving general anesthesia (GA). However, a limited number of studies have evaluated the effects of local anesthetics (LA) on tooth extraction procedures during GA. There is no consensus in the literature regarding LA application in the perioperative period for dental treatments performed within the scope of GA.

Aim:
This study aimed to determine the retrospective physiologic effects of fluctuations in vital signs and postoperative bleeding in children who did or did not receive LA for tooth extraction under GA.

Methods:
A retrospective evaluation of 77 patients aged 5.16 ± 1.85 years who had the extraction of primary posterior teeth with or without LA under GA were reviewed in the post-anaesthesia care unit (PACU) for postoperative bleeding and the effects of intraoperative LA on fluctuations in postoperative parameters such as mean arterial pressure (MAP), heart rate (HR), peripheral oxygen saturation (SpO2), respiratory rate (RR), and the end-tidal carbon dioxide (EtCO2). These were compiled from the patient records of the procedures.

Results:
Significant differences between the baseline and peak MAP (P < 0.001), HR (P = 0.011), and EtCO2 (P = 0.002) were noted in children without LA compared to those who had LA. In addition, substantial variations were observed between the baseline and peak values for MAP (P < 0.001) and HR (P = 0.037) in children who had tooth extraction in the mandibular region. Statistically significant differences were noted between the baseline and peak values for patients who did not receive LA before the extraction of the first primary molar in terms of MAP (P < 0.02) and EtCO2 (P = 0.032). Similarly, significant differences in MAP (P < 0.02) and EtCO2 (P = 0.034) were noted in the extraction of the second primary molar. In addition, there was a significant difference in bleeding based on the number of tooth extractions in those who did not receive LA (P = 0.020).

Conclusion:
This study showed that in children who underwent tooth extraction under GA, additional LA application minimized changes in HR, MAP, and EtCO2, whereas a lack of LA application produced significant fluctuations from baseline to peak values of HR, MAP, and EtCO2. In addition, LA application reduced postoperative bleeding.
Gender Estimation from Morphometric Measurements of Mandibular Lingula by Using Machine Learning Algorithms and Artificial Neural Networks
Authors: Şenol D , Bodur F , Seçgin Y , Şencan D , Duman ŞB , Öner Z 
Published: June 2024

Background:
Sex determination from the bones is of great importance for forensic medicine and anthropology. The mandible is highly valued because it is the strongest, largest and most dimorphic bone in the skull.

Aim:
Our aim in this study is gender estimation with morphometric measurements taken from mandibular lingula, an important structure on the mandible, by using machine learning algorithms and artificial neural networks.

Methods:
Cone beam computed tomography images of the mandibular lingula were obtained by retrospective scanning from the Picture Archiving Communication Systems of the Department of Oral, Dental and Maxillofacial Radiology, Faculty of Dentistry, İnönü University. Images scanned in Digital Imaging and Communications in Medicine (DICOM) format were transferred to RadiAnt DICOM Viewer (Version: 2020.2). The images were converted to 3-D format by using the 3D Volume Rendering console of the program. Eight anthropometric parameters were measured bilaterally from these 3-D images based on the mandibular lingula.

Results:
The results of the machine learning algorithms analyzed showed that the highest accuracy was 0.88 with Random Forest and Gaussian Naive Bayes algorithm. Accuracy rates of other parameters ranged between 0.78 and 0.88.

Conclusions:
As a result of the study, it is thought that mandibular lingula-centered morphometric measurements can be used for gender determination as well as bones such as the pelvis and skull as they were found to be highly accurate. This study also provides information on the anatomical position of the lingula according to gender in Turkish society. The results can be important for oral-dental surgeons, anthropologists, and forensic experts.
Low Pressure versus Standard Pressure Pneumoperitoneum in Laparoscopic Appendectomy: A Randomized Controlled Trial
Authors: Adenuga AT , Olakada F , Ojo C , Aniero J 
Published: June 2024

Background:
The creation of pneumoperitoneum using higher pressure is believed to be associated with increased postoperative abdominal pain.

Aim:
This study aimed to compare postoperative abdominal pain following low pressure laparoscopic appendectomy and standard pressure laparoscopic appendectomy.

Methods:
This was a prospective, double-blind, randomized controlled trial of 54 patients aged between 18 and 56 years with clinical and/or radiologic diagnosis of acute appendicitis. The patients were randomly allocated to two groups: low pressure laparoscopic appendectomy (n = 26) and standard pressure laparoscopic appendectomy (n = 28). The intra-abdominal pressure was kept in either low pressure (9 mm Hg) or standard pressure (13 mm Hg). Abdominal and shoulder pain scores were assessed using the visual analog scale at 6 hours and 3 days post procedure. Postoperative analgesia requirement, duration of surgery, complications, and hospital stay were recorded.

Results:
Both groups match for the demographic parameters. Three patients required conversion from low to standard pressure. There was no difference between the two groups in terms of abdominal pain (P = 0.86) and shoulder pain (P = 0.33), duration of surgery (P = 0.51), complications (P = 0.17), and length of hospital stay (P = 0.83).

Conclusion:
The use of low pressure pneumoperitoneum did not reduce the incidence of abdominal pain in patients who had laparoscopic appendectomy. Patients with acute appendicitis can be treated with either low or normal pressure pneumoperitoneum depending on the experience of the surgeon.
The Prognostic Significance of Tumor SUVmax Value in Pre- and Post-Chemoradiotherapy 18F-FDG PET/CT Imaging in Patients with Localized and Advanced Head and Neck Squamous Cell Carcinoma
Authors: Kandemir O , Demir F , Avcı GG 
Published: June 2024

Background:
Some parameters of 18F-2-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography (18F-FDG PET/CT) can predict tumor chemosensitivity and survival in patients with head and neck squamous cell carcinoma (HNSCC).

Aim:
The aim of the study was to investigate the prognostic value of pre- and post-treatment maximum standardized uptake values (SUVmax) in 18F-FDG PET/CT imaging for predicting mortality in patients with HNSCC, as well as its prognostic value in terms of disease progression, overall survival (OS), and progression-free survival (PFS).

Methods:
This retrospective study included 37 patients with a histopathological diagnosis of HNSCCs between 2015 and 2018. In patients with HNSCC, the first 18F-FDG PET/CT imaging was performed for pre-treatment staging, and the second imaging was performed to evaluate post-treatment response. In these imaging studies, SUVmax values of the primary tumor before and after treatment were determined. After the second imaging, patients were re-evaluated and followed up. ROC analysis was used to determine the predictive value of 18F-FDG PET/CT SUVmax parameters in terms of death and progression, and Cox regression analysis was used to investigate the prognostic value in terms of OS and PFS.

Results:
Cut-off value 15 for SUVmax1 (pre-treatment) had a significant predictive value for mortality (P = 0.02). Cut-off value 3.1 for SUVmax2 (post-treatment) had a significant predictive value for progression (P = 0.024). In univariate analysis, both SUVmax1 and SUVmax2 values were significant prognostic factors for OS (P = 0.047, P = 0.004). However, for PFS, only the SUVmax2 value was a significant prognostic factor (P = 0.001).

Conclusion:
SUVmax1 value of the primary tumor at diagnosis in HNSCC patients has a predictive value for mortality and a prognostic value for OS. However, the SUVmax2 value in the primary tumor after treatment is a predictive factor for progression and a prognostic factor for both OS and PFS.
Hepatitis B virus serology in first-degree relatives and spouses of patients with hepatocellular carcinoma at a Nigerian hospital
Authors: Asaolu Olutoyin Iretiola , Odeghe Emuobor Aghoghor , Oyeleke Ganiyat K. , Onyekwere Charles A. , Lesi Olufunmilayo A. 
Published: June 2024

Abstract

Background:
The link between hepatitis B virus (HBV) infection and hepatocellular carcinoma (HCC) has been well established. There is a dearth of scientific data on the important phenomenon of familial clustering of these diseases in sub-Saharan Africa. This study evaluated the prevalence and risk of HBV infection in first-degree relatives and spouses of patients with HCC.

Materials and Methods:
This case–control study was conducted in a Nigerian hospital. A total of 211 first-degree relatives and spouses of confirmed 110 patients with HCC and 212 matched controls were consecutively recruited. All participants were screened for the HBV serological markers using the Aria lateral immunoassay kits. Logistic regression was used to determine the odds ratio while bivariate analysis was used to calculate χ2.

Results:
The prevalence of HBsAg was higher in the first-degree relatives and spouses of patients with HCC than in the controls (17.1% versus 3.3%, P < 0.001, odds ratio 5.9, 95% confidence interval (CI): 2.6–13.7). Among the relatives, the prevalence of HBsAg positivity was highest in the parents and siblings of HCC patients compared with the children and spouses (P < 0.0001). Furthermore, the relatives of female index patients had a higher prevalence of HBV than the relatives of the male HCC patients (75.0% versus 27.0%, p = 0.012). Significant risks for HBV infection included lower vaccination rate, low educational status and tattoo acquisition (p = 0.006, 0.010 and 0.023 respectively).

Conclusion:
This study provides important local-based population data (perhaps the first of its kind) supporting the scientific postulation of familial clustering of HBV infection and HCC. It also underscores the importance of targeting first-degree relatives and spouses of patients with HCC for HBV screening to reduce the infection and its sequelae.
Nonalcoholic fatty liver disease in Sub-Saharan Africa: A descriptive study of the range of histopathological findings in the South-West zone of Nigeria
Authors: Ojo Olusegun Sylvester , Adekanle Olusegun , Ndububa Dennis , Kolawole Olawunmi , Betiku Omolade Adefolabi 
Published: June 2024

Abstract

Background:
Nonalcoholic fatty liver disease (NAFLD) is increasingly becoming a public health problem worldwide. It has been shown that a very strong link exists between NAFLD and the risk of other systemic diseases. Currently, data on the incidence of NAFLD are limited in much of sub-Saharan, whereas hepatitis B virus (HBV) infections are also endemic. Thus, there is an impelling need to assess if NAFLD makes any significant contribution to the severity of HBV-associated chronic liver disease (CLD) in patients who develop NAFLD simultaneously.

Aim:
This study described the range of histopathological findings in NAFLD and assessed the impact of NAFLD on the severity of HBV-associated chronic hepatitis.

Materials and Methods:
We retrospectively studied 120 cases of histologically diagnosed NAFLD within a 4-year study period from May 31, 2018 to April 30, 2022. Brunt Scoring System was used to grade and stage NAFLD cases with or without chronic hepatitis B (CHB) infection in each case. Data were analyzed using descriptive and Chi-t tests.

Results:
The results revealed that the mean age was 45.78 ± 12.29 years with a female predominance. HBV-associated CLD patients with histological diagnosis of NAFLD were present in 55 (45.83%), and NAFLD in patients without CHB was 54.16%. There was a statistically significant association between the older age group with the cohort cases with NAFLD without associated CHB infection (P < 0.001). The grading and fibrosis stage was found not to be related to the age group or gender among any of the cohorts of cases.

Conclusion:
This study concludes that the histological range primarily includes steatosis with or without lobular and portal inflammation or fibrosis as well as ballooned hepatocytes. There is no statistically significant difference in the grade and stage between NAFLD patients without CHB and HBV-associated CLD patients with histological features of NAFLD. However, the grade tends to be higher in NAFLD patients without CHB, whereas the fibrosis level tends to be higher in cases of HBV-associated CLD patients with histological NAFLD.
Entre a Música e a Política:
Authors: Da Silveira Prado e Figueiredo Maria Clara 
Published: June 2024

A historiadora Natália Ayo Schmiedecke publicou em 2022 o livro Chilean New Song and the Question of Culture in the Allende Government. Voices for a Revolution, a obra busca refletir sobre as políticas culturais e as expressões artísticas durante o governo de coalizão socialista de Salvador Allende Gossens. Observando o papel da cultura para a proposta de transição política e, consequentemente, quais espaços ocuparam os artistas junto ao governo, Schmiedecke empreende uma análise detalhada de projetos culturais, músicas e revistas, ao passo que suas reflexões complexificam as dinâmicas entre política, cultura e atuação artística e partidária durante a experiência da Unidade Popular no Chile.