bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cerebral Atrophy is an Independent Risk Factor for Unfavorable Outcome After Spontaneous Supratentorial Intracerebral Hemorrhage
Authors: Herweh Christian , Prager Eric , Sykora Marek , Bendszus Martin 
Published: February 2013

Background and Purpose—
To investigate the influence of cerebral atrophy on clinical outcome in patients with supratentorial intracerebral hemorrhage.

Methods—
Computed tomography scans of 320 patients included in a prospective, multicenter trial were used for a segmentation analysis to determine the supratentorial cerebral volume. A logistic regression analysis was used to explore its effect on outcome after 90 days in addition to other clinical and imaging parameters.

Results—

Cerebral volume loss significantly reduced the odds for favorable outcome after 90 days (odds ratio=0.91; confidence interval, 0.85–0.99;
P
=0.02).

Conclusions—
Cerebral atrophy is an independent predictor of unfavorable outcome after intracerebral hemorrhage, indicating reduced functional recovery potential in these individuals.
Institutional Conflict and the Bolivarian Revolution
Authors: Nelson Marcel 
Published: February 2013

A case study of the shift in Venezuela’s attitude toward the negotiation of the Free Trade Area of the Americas sheds light on Jorge Castañeda’s distinction between a “wrong left” and a “right left” in Latin America. Castañeda’s reliance on the “origins” of Latin American leaders as the primary explanation for their governance styles is both deterministic and incomplete. By employing Nicos Poulantzas’s “relational” approach to the state, which conceptualizes the state as a strategic field of social relations, it becomes possible to conceive that the policies and governance styles of leftist governments in Latin America are as much the result of pressures emanating from the institutions of the state as of the origins of their leaders. Un estudio del caso del cambio en la actitud venezolana a las negociaciones del Acuerdo de Libre Comercio de las Américas demuestra la distinción que hiciera Jorge Castañeda entre una “mala izquierda” y una “buena izquierda” en América Latina. La dependencia de Castañeda en el tema del “origen” de los líderes latinoamericanos para explicar sus estilos de gobernar es determinista e incompleta. Empleando el acercamiento “relacional” al Estado de Nicos Poulantzas, según el cual el Estado se ve como un campo estratégico de relaciones sociales, es posible concebir que las políticas y los estilos de gobernar de los gobiernos de izquierda latinoamericanos sean tanto el resultado de presiones emanantes de las instituciones del Estado como del origen de sus líderes.
Roles and Strategies of Diabetes Support Group Facilitators
Authors: Costello Joanne F. 
Published: February 2013

Purpose The purpose of the study was to explore the roles and strategies implemented by diabetes support group facilitators. Methods A descriptive exploratory design that included 2 in-depth interviews and 1 group interview of 6 diabetes support group facilitators was implemented over a 2-month period. Results The participants described the role of facilitator as involving 4 major aspects: (1) a philosophy of shared authority and group ownership; (2) a conception of diabetes as a highly complex disease interconnected with all aspects of one’s life; (3) a focus on quality of life; and (4) recognition of perfectionism as neither possible nor desirable in self-management. These role aspects formed the context for facilitator strategies in working with support groups. Four strategies were identified based on the individual and group interviews: (1) connecting, (2) exchanging information, (3) managing group dynamics, and (4) promoting problem solving. A facilitator support group model was developed from the study results. Conclusions A clear need exists to develop and teach best practices for support group facilitation. Education in this area should occur systematically at the baccalaureate and master’s levels as the role of health providers increasingly expands to include populations living with chronic diseases. Health care providers who are functioning in this role need continuing education to provide proficient care in this area of practice.
Sexual Health and Overall Wellness (SHOW) survey in men and women in selected European and Middle Eastern countries
Authors: Dean John , Shechter Arik , Vertkin Arkadiy , Weiss Petr , Yaman Onder , Hodik Michal , Ginovker Anna 
Published: February 2013

Objective To investigate whether better sexual health is associated with improvements in overall health and wellness, a more loving and intimate relationship, and a more positive outlook on life. Methods The Sexual Health and Overall Wellness survey used self-administered questionnaires to collect data from men and women aged 25–74 years who had had sexual intercourse at least once within the previous 12 months. Results Across nine countries, 3780 self-administered questionnaires were completed: 1893 from men (mean age, 44.6 years); 1887 from women (mean age, 44.2 years). The majority of men and women were satisfied with the frequency of sexual intercourse over the previous 4 weeks (59% and 66%, respectively); the majority (67% and 55%, respectively) reported that having sex was ‘very important’ or ‘absolutely essential’. For men and women, there was a strong association between satisfaction with sex and overall health, and between satisfaction with sex and an overall positive outlook on life. Conclusion For men and women, satisfaction with different aspects of sex was important, and was strongly associated with satisfaction with general health, relationships and other aspects of wellbeing.
The angiotensin-converting enzyme insertion/deletion polymorphism and susceptibility to rheumatoid arthritis, vitiligo and psoriasis: A meta-analysis
Authors: Song Gwan Gyu , Bae Sang-Cheol , Kim Jae-Hoon , Lee Young Ho 
Published: February 2013

Introduction: The purpose of this study was to examine whether the insertion (I) and deletion (D) of angiotensin-converting enzyme ( ACE) polymorphism confers susceptibility to psoriasis, vitiligo and rheumatoid arthritis (RA). Materials and methods: A meta-analysis was conducted on the association between the ACE I/D polymorphisms and psoriasis, vitiligo and RA. Results: Fifteen studies comprising five on psoriasis, five on vitiligo and five on RA were available for the meta-analysis consisting of 2094 cases and 2871 controls. Meta-analysis of the DD+ID genotype showed significant associations with psoriasis (odds ratio (OR) 0.753, 95% confidence interval (CI) 0.601–0.921, p = 0.006). Meta-analysis showed no association between vitiligo and the ACE I/D polymorphism. Meta-analysis of the DD+ID genotype showed an association with RA (OR 2.199, 95% CI 1.379–3.506, p = 0.001). Ethnicity-specific meta-analysis of the D allele showed no association with psoriasis in Europeans, and vitiligo in South Asians. However, subgroup analysis by ethnicity revealed a significant association between the D allele and RA in Arab populations (OR 2.697, 95% CI 1.803–4.034, p = 1.3 × 10−5). Conclusions: Our meta-analysis demonstrates that the ACE I/D polymorphism is associated with susceptibility to RA, especially in Arab populations.
A phase II, sham-controlled, double-blinded study testing the safety and efficacy of the coronary sinus reducer in patients with refractory angina: study protocol for a randomized controlled trial
Authors: Jolicœur E Marc , Banai Shmuel , Henry Timothy D , Schwartz Marc , Doucet Serge , White Christopher J , Edelman Elazer , Verheye Stefan 
Published: February 2013

AbstractBackgroundA growing population of patients lives with severe coronary artery disease not amenable to coronary revascularization and with refractory angina despite optimal medical therapy. Percutaneous reduction of the coronary sinus is an emerging treatment for myocardial ischemia that increases coronary sinus pressure to promote a transcollateral redistribution of coronary artery in-flow from nonischemic to ischemic subendocardial territories. A first-in-man study has demonstrated that the percutaneous reduction of the coronary sinus can be performed safely in such patients. The COSIRA trial seeks to assess whether a percutaneous reduction of the coronary sinus can improve the symptoms of refractory angina in patients with limited revascularization options.Methods/DesignThe COSIRA trial is a phase II double-blind, sham-controlled, randomized parallel trial comparing the percutaneously implanted coronary sinus Reducer (Neovasc Inc, Richmond, BC, Canada) to a sham implantation in 124 patients enrolled in Canada, Belgium, England, Scotland, Sweden and Denmark. All patients need to have stable Canadian Cardiovascular Society (CCS) class III or IV angina despite optimal medical therapy, with evidence of reversible ischemia related to disease in the left coronary artery, and a left ventricular ejection fraction >25%. Participants experiencing an improvement in their angina ≥2 CCS classes six months after the randomization will meet the primary efficacy endpoint. The secondary objective of this trial is to test whether coronary sinus Reducer implantation will improve left ventricular ischemia, as measured by the improvement in dobutamine echocardiogram wall motion score index and in time to 1 mm ST-segment depression from baseline to six-month post-implantation.DiscussionBased on previous observations, the COSIRA is expected to provide a significant positive result or an informative null result upon which rational development decisions can be based. Patient safety is a central concern and extensive monitoring should allow an appropriate investigation of the safety related to the coronary sinus Reducer.Trial registrationClinicalTrials.gov identifier -NCT01205893.
Coughing-induced bowel transection in a patient with an incarcerated inguinal hernia: a case report
Authors: Hakiman Hekmat , DeLibero Jana , Pham Thai , Dineen Sean , Huerta Sergio 
Published: February 2013

Abstract

Introduction
Although blunt trauma to a hernia-containing bowel is known to cause bowel perforation, this report documents the first incident of a small bowel transection following a non-traumatic event.

Case presentation
We report the case of a 49-year-old African American man with a chronic incarcerated inguinal hernia awaiting elective repair. He presented to the Emergency Department with abdominal pain following an episode of coughing. On examination, he was found to have peritonitis. He underwent exploratory laparotomy, and had a complete small bowel transection. A bowel resection with primary anastomosis was performed, as well an inguinal hernia repair.

Conclusion
Chronic hernia incarceration can lead to weakening and ischemia of the bowel, and minimal trauma can lead to perforation of the weakened segment. In such presentations, bowel resection and repair of the defect with a biological material is safe and feasible.
An endonasal approach to the resection of a papillary seromucinous adenocarcinoma of the Eustacian tube
Authors: Glicksman Jordan T , Franklin Jason H , Shepherd Jessica , Rotenberg Brian W 
Published: February 2013

Objectives Papillary seromucinous adenocarcinoma of the sinonasal tract is exceedingly rare. The objectives of this case report are to describe a case of papillary seromucinous adenocarcinoma presenting in the nasopharynx and to review the literature pertaining to other similar cases. Methods A review of the patient's chart and a review of the English literature were conducted. Results We describe the case of a 64 year-old woman who presented with a 3-year history of epistaxis and right-sided otitis media with effusion. The patient had been followed for a known nasopharyngeal mass that had twice been biopsied and in both cases was considered a benign mass pathologically. A third biopsy was diagnosed as a low-grade papillary seromucinous adenocarcinoma. The patient was otherwise asymptomatic. The patient was referred to a multidisciplinary cancer clinic at which endoscopic resection was determined to be the preferred treatment modality. A literature review and approach to patients with nasopharyngeal masses will be presented. Conclusions Papillary seromucinous adenocarcinoma is a rare tumor that can present in the nasopharynx. We describe the endoscopic surgical management of one such patient that presented to our care.
Bisphenol A stimulates human prostate cancer cell migration via remodelling of calcium signalling
Authors: Derouiche Sandra , Warnier Marine , Mariot Pascal , Gosset Pierre , Mauroy Brigitte , Bonnal Jean-Louis , Slomianny Christian , Delcourt Philippe , Prevarskaya Natalia , Roudbaraki Morad 
Published: February 2013

AbstractBisphenol A (BPA), the principal constituent of reusable water bottles, metal cans, and plastic food containers, has been shown to be involved in human prostate cancer (PCa) cell proliferation. The aim of the present study was to explore the effect of BPA on PCa cell migration and the pathways involved in these processes. Using the transwell technique, we clearly show for the first time that the pre-treatment of the cells with BPA (1–10 nM) induces human PCa cell migration. Using a calcium imaging technique, we show that BPA pre-treatment induces an amplification of Store-Operated Calcium Entry (SOCE) in LNCaP cells. RT-PCR and Western blot experiments allowed the identification of the ion channel proteins which are up-regulated by BPA pre-treatments. These include the Orai1 protein, which is known as an important SOCE actor in various cell systems, including human PCa cells. Using a siRNA strategy, we observed that BPA-induced amplification of SOCE was Orai1-dependent. Interestingly, the BPA-induced PCa cell migration was suppressed when the calcium entry was impaired by the use of SOCE inhibitors (SKF96365, BTP2), or when the extracellular calcium was chelated. Taken together, the results presented here show that BPA induces PCa cells migrationviaa modulation of the ion channel protein expression involved in calcium entry and in cancer cell migration. The present data provide novel insights into the molecular mechanisms involved in the effects of an environmental factor on cancer cells and suggest both the necessity of preventive measures and the possibility of targeting ion channels in the treatment of PCa cell metastasis.
RETRACTED ARTICLE: Mobile phone text messaging and Telephone follow-up in type 2 diabetic patients for 3 months: a comparative study
Authors: Zolfaghari Mirta , Mousavifar Seyedeh A , Haghani Hamid 
Published: February 2013

Abstract
Background
To investigate and to compare the effectiveness of a nurse short message service (SMS) by cellular phone and telephone follow-up by nurse on Glycosylated hemoglobin (HbA1c) levels in people with type 2 diabetes.

Methods
Semi experimental study consisted of 77 patients with type 2 diabetes that randomly assigned to two groups: telephone follow-up (n = 39) and short message service (n = 38). Telephone interventions were applied by researcher for 3 months. SMS group that received message daily for 12 weeks. Data gathering instrument include data sheet to record HbA1c and questionnaire that consisted of demographic characteristics. Data gathering was performed at two points: initial the study and after 12 weeks. Data analyzed using descriptive and inferential statistics methods with SPSS version 11.5.

Results
Demographic variables were compared and all of them were homogenous. Results of this study showed that both interventions had significant mean changes in HbA1c; for the telephone group (p = 0.001), with a mean change of −0.93% and for the SMS group (p = 0.001), with a mean change of −1.01%.

Conclusion
Finding of this research showed that intervention using SMS via cellular phone and nurse-led-telephone follow up improved HbA1c for three months in type 2 diabetic patients and it can consider as alternative methods for diabetes control.
Concise Synthesis of the Tetracyclic Framework of Azadiradione: Tandem Radical Cyclization Route
Authors: Yamashita Shuji , Naruko Akito , Yamada Takahiro , Hayashi Yujiro , Hirama Masahiro 
Published: February 2013

Abstract
Azadiradione, a limonoid isolated from the neem plant, possesses a unique stereostructure distinct from that of the steroids. We describe a concise synthesis of the tetracyclic framework of azadiradione by a tandem radical cyclization process.
Design and Synthesis of Novel Piperazine Derivatives with High Antibacterial Activity
Authors: Zhang Maolan , Wang Yuanliang , Sun Jiaoxia , Wu Jinchuan , Yan Weiwei , Zheng Yuxi 
Published: February 2013

Abstract
A novel antibacterial piperazine derivative (PE-B) has been prepared via the nucleophilic substitution reaction of poly(ethylenediaminetetraacetic dianhydride-co-piperazine) (PE) with n-butyl bromide. PE was synthesized by a condensation polymerization reaction of ethylenediaminetetraacetic dianhydride (EDTAD) and piperazine (PA). The thermoresponsive test results showed that the PE was thermoresponsive; however, when it was quaternized by n-butyl bromide, this performance disappeared. The antibacterial test results showed that both the PE and PE-B exhibited potent inhibitory activity on S. aureus and E. coli. Specifically, PE had better antibacterial ability against S. aureus, but PE-B showed similar antibacterial activity against S. aureus and E. coli.
Nonrandom Distribution of Interhomolog Recombination Events Induced by Breakage of a Dicentric Chromosome inSaccharomyces cerevisiae
Authors: Song Wei , Gawel Malgorzata , Dominska Margaret , Greenwell Patricia W , Hazkani-Covo Einat , Bloom Kerry , Petes Thomas D 
Published: February 2013

AbstractDicentric chromosomes undergo breakage in mitosis, resulting in chromosome deletions, duplications, and translocations. In this study, we map chromosome break sites of dicentrics in Saccharomyces cerevisiae by a mitotic recombination assay. The assay uses a diploid strain in which one homolog has a conditional centromere in addition to a wild-type centromere, and the other homolog has only the wild-type centromere; the conditional centromere is inactive when cells are grown in galactose and is activated when the cells are switched to glucose. In addition, the two homologs are distinguishable by multiple single-nucleotide polymorphisms (SNPs). Under conditions in which the conditional centromere is activated, the functionally dicentric chromosome undergoes double-stranded DNA breaks (DSBs) that can be repaired by mitotic recombination with the homolog. Such recombination events often lead to loss of heterozygosity (LOH) of SNPs that are centromere distal to the crossover. Using a PCR-based assay, we determined the position of LOH in multiple independent recombination events to a resolution of ∼4 kb. This analysis shows that dicentric chromosomes have recombination breakpoints that are broadly distributed between the two centromeres, although there is a clustering of breakpoints within 10 kb of the conditional centromere.
Calcium Absorption Response to Cholecalciferol Supplementation in Hemodialysis
Authors: Armas Laura A.G. , Zena Mohsen , Lund Richard , Heaney Robert P. 
Published: February 2013

Summary

Background and objectives
Recent understanding of extrarenal production of calcitriol has led to the use of more vitamin D supplementation in CKD populations. This paper reports the effect of cholecalciferol supplementation on calcium absorption.

Design, setting, participants, & measurements
Paired calcium absorption tests were done before and after 12–13 weeks of 20,000 IU weekly cholecalciferol supplementation in 30 participants with stage 5 CKD on hemodialysis. The study was conducted from April to December of 2011. Calcium absorption was tested with a standardized meal containing 300 mg calcium carbonate intrinsically labeled with 45Ca; 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D were measured.

Results
25-Hydroxyvitamin D rose from 14.2 ng/ml (11.5–18.5) at baseline to 49.3 ng/ml (42.3–58.1) at the end of the study (P<0.001). 1,25-Dihydroxyvitamin D rose from 15.1 (10.5–18.8) pg/ml at baseline to 20.5 (17.0–24.7) pg/ml at the end of the study (P<0.001). The median baseline calcium absorption was 12% (7%–17%) and 12% (7%–16%) at the end of study.

Conclusions
Patients with stage 5 CKD on hemodialysis had very low calcium absorption values at baseline, and cholecalciferol supplementation that raised 25(OH)D levels to 50 ng/ml had no effect on calcium absorption.
Sociocultural Influences on Diabetes Self-Management Behaviors in Older African Americans
Authors: Rovner Barry W. , Casten Robin J. , Harris Lynn Fields 
Published: February 2013

Objective. The purpose of this observational study was to describe the associations between cultural beliefs that are prevalent in older African Americans and adherence to diabetes self-management (DSM) behaviors.
Methods. In a community population of 110 older African Americans with type 2 diabetes, the investigators administered surveys that assess present time orientation (PTO), future time orientation (FTO), and religiosity, as well as exercising habits, reading food labels, and checking blood glucose.
Results. Participants who reported regularly exercising had significantly lower PTO scores and higher FTO and religiosity scores than participants who did not regularly exercise. Similarly, participants who reported reading food labels had lower PTO scores and higher FTO scores but did not differ in religiosity. Participants who reported checking blood glucose levels tended to have higher FTO scores but did not differ in PTO or religiosity. Participants who engaged in all three DSM behaviors had significantly lower PTO scores and higher FTO and religiosity scores.
Conclusion. These data indicate that cultural diversity within older African Americans may influence DSM behaviors and contribute to disparities in diabetes outcomes in this high-risk population. Efforts to prevent complications of diabetes might benefit from consideration of these cultural factors.
Comparative studies on the removal of copper (II) by Ulva fasciata activated carbon and commercially activated carbon
Authors: Suresh Jeyakumar R.P. , Chandrasekaran V. 
Published: February 2013

Abstract
In this work, the efficiency of Ulva fasciata sp. activated carbons (CCUC, SCUC and SSUC) and commercially activated carbon (CAC) were studied for the removal of Cu (II) ions from synthetic wastewater. Batch adsorption experiments were carried out as a function of pH, contact time, initial copper concentration and adsorbent dose. The percentage adsorption of copper by CCUC, SSUC, SCUC and CAC are 88.47%, 97.53%, 95.78% and 77.42% respectively. Adsorption data were fitted with the Langmuir, Freundlich and Temkin models. Two kinetic models pseudo first order and the pseudo second order were selected to interpret the adsorption data.
Iranian Thrips of the Family Aeolothripidae (Insecta, Thysanoptera), with Four Newly Recorded Species
Authors: Mirab-Balou M. , Chen X.-X. 
Published: February 2013

Abstract
The family Aeolothripidae (Thysanoptera, Terebrantia) included seventeen species in four genera from Iran. Here, four species are recorded from Iran for the first time: Aeolothrips albicinctus Haliday, A. cursor Priesner, A. montivagus Priesner and A. gloriosus Bagnall. A checklist of all Iranian species of the family Aeolothripidae, with geographical distributions for each species is provided. New distribution records of eight species in Iran are reported.