bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of the electric field on the free volume investigated from positron annihilation lifetime and dielectric properties of sulfonated PVC/PMMA
Authors: Elsharkawy Mohamed R. M. , Mohammed Wael M. 
Published: July 2024

AbstractPolymer electrolyte membranes (PEMs) play a vital role in electrochemical devices, facilitating ion conduction while blocking gases and electrons. Their effectiveness is closely linked to their microstructural properties, especially the free volume, which impacts ionic conductivity, mechanical strength, and overall device performance. This study examines the behavior of PVC/PMMA/SSA blends under electric fields, using Positron Annihilation Lifetime Spectroscopy (PALS) to assess free volume and dielectric properties. The study involved preparing and characterizing membranes through x‐ray diffraction (XRD), thermogravimetric analysis (TGA), and PALS. XRD results indicated semi‐crystalline structures with changes in intensity due to temperature variations, while TGA highlighted changes in thermal stability under different electric fields. PALS measurements showed that free volume varied with temperature and electric field strength, influencing the material's dielectric and mechanical characteristics. The results revealed that higher electric fields reduced free volume while enhancing dielectric properties. The dielectric constant and loss were found to depend on frequency, which was affected by the polar SO3H groups. Impedance spectroscopy provided further insights into the electrical properties, showing increased dc conductivity with stronger electric fields. A correlation between the free volume investigated from PAL and the electrical properties was observed. This study emphasizes the significance of free volume and external electric field in optimizing PEMs for advanced energy applications.
Metabolomics‐based profiling of five Salvia L. (Lamiaceae) species using untargeted data analysis workflow
Authors: Kharazian Navaz , Dehkordi Farzaneh Jafari , Xiang Chun‐Lei 
Published: July 2024

AbstractIntroductionThe genus Salvia L., a member of the family Lamiaceae, is a keystone genus with a wide range of medicinal properties. It possesses a rich metabolite source that has long been used to treat different disorders.ObjectivesDue to a deficiency of untargeted metabolomic profiling in the genus Salvia, this work attempts to investigate a comprehensive mass spectral library matching, computational data annotations, exclusive biomarkers, specific chemotypes, intraspecific metabolite profile variation, and metabolite enrichment by a case study of five medicinal species of Salvia.Material and methodsAerial parts of each species were subjected to QTRAP liquid chromatography–tandem mass spectrometry (LC–MS/MS) analysis workflow based on untargeted metabolites. A comprehensive and multivariate analysis was acquired on the metabolite dataset utilizing MetaboAnalyst 6.0 and the Global Natural Products Social Molecular Networking (GNPS) Web Platform.ResultsThe untargeted approach empowered the identification of 117 metabolites by library matching and 92 nodes annotated by automated matching. A machine learning algorithm as substructural topic modeling, MS2LDA, was further implemented to explore the metabolite substructures, resulting in four Mass2Motifs. The automated library newly discovered a total of 23 metabolites. In addition, 87 verified biomarkers of library matching, 58 biomarkers of GNPS annotations, and 11 specific chemotypes were screened.ConclusionIntegrative spectral library matching and automated annotation by the GNPS platform provide comprehensive metabolite profiling through a workflow. In addition, QTRAP LC–MS/MS with multivariate analysis unveiled reliable information about inter and intraspecific levels of differentiation. The rigorous investigation of metabolite profiling presents a large‐scale overview and new insights for chemotaxonomy and pharmaceutical studies.
Uniaxial tensile‐induced deformation of spherulite: combining experimental and simulation methods
Authors: Yuan Maoqing , Ren Linjuan , Zhao Na , Liu Yanping , Li Qian 
Published: July 2024

AbstractA combination of experimental and simulation methods is adopted to study the relationship between micro‐stress and micro‐strain of a single spherulite upon uniaxial tensile deformation. To verify the simulation results and establish a suitable spherulite model, large‐sized isotactic polypropylene spherulite is first cultured with isothermal crystallization, whose structural deformation upon application of uniaxial tension is recorded using a polarizing optical microscope. A nanoindenter is used to measure the elastic modulus of the spherulite and amorphous region, preparing the property parameters for numerical simulation. Modeling and meshing of the single spherulite are conducted with the finite element software ABAQUS. The entire deformation of the spherulite is analyzed with fixed strain as the boundary condition, and the microscopic stress and strain distribution inside and outside of the spherulite is obtained. The higher micro‐stress region mainly locates at two poles in the equatorial direction, where might be the origin of craze. Generally, the simulation result is basically consistent with the experimental deformation process, which provides a new idea for the study of microscale structure and performance. © 2024 Society of Chemical Industry.
18F‐FDG accumulation at the early onset of acute exacerbation of idiopathic interstitial pneumonia on 18F‐FDG PET/CT: A case report
Authors: Akaike Kimitaka , Saruwatari Koichi , Sakata Shinya , Oda Seitaro , Shiraishi Shinya , Iyama Shinji , Masunaga Aiko , Tomita Yusuke , Ichiyasu Hidenori , Sakagami Takuro 
Published: July 2024

AbstractAcute exacerbation of idiopathic interstitial pneumonias (AE‐IIPs) is a disease associated with a poor prognosis in patients with IIPs. However, the specific characteristics of fluorine‐18 2‐fluoro‐2‐deoxy‐d‐glucose (18F‐FDG) positron emission tomography/computed tomography (PET/CT) imaging for AE‐IIPs remain unclear. Herein, we present the case of a patient with lung cancer combined with IIPs who underwent 18F‐FDG PET/CT at the early onset of AE‐IIPs. The scan, conducted 18 days post‐bronchoscopy for lung cancer evaluation, revealed AE‐IIPs before the onset of respiratory failure. New ground‐glass opacities appeared, accompanied by significant 18F‐FDG accumulation extending beyond these regions. To the best of our knowledge, this report represents the first assessment of 18F‐FDG PET/CT images at the early onset of AE‐IIPs before respiratory failure in humans. The observed features in this PET image could potentially contribute to our understanding of the pathophysiology of AE‐IIPs.
Addressing the Role of “Linguistic Knowledge” in Global Englishes Pedagogy
Authors: Suzuki Yuichi , Crowther Dustin 
Published: July 2024

AbstractOne key tenet of Global Englishes for Language Teaching (GELT) is that the native English speaker should no longer serve as the role model for second language (L2) English users. Such a view does not discount that some degree of linguistic knowledge is necessary for successful global communication. However, GELT scholarship has remained relatively silent on the process and product of L2 acquisition. In this paper, we propose integrating L2 acquisition theory into GELT pedagogical practices without relying on theoretical perspectives steeped in some form of native speakerism. At the heart of our discussion is the concept of linguistic knowledge–implicit (unconscious) and explicit (conscious)–emphasizing the role of explicit learning processes in GELT classrooms rather than adhering solely to the idealistic goal of implicit competence. Because L2 learners need to reflect on linguistic knowledge (repertoire) and strategies for effective global communication, we propose that their learning should aim to develop skill sets of using explicit and implicit knowledge dynamically and efficiently in varied communicative contexts. We argue that skill acquisition theory offers a useful framework for GELT, as it can account for the development of automatized explicit knowledge alongside implicit knowledge, aligning with GELT objectives of fostering multicompetent English users. We illustrate how this perspective can inform classroom activities such as shadowing and task repetition. These activities not only promote deliberate, explicit learning processes but also integrate seamlessly with awareness–raising activities commonly employed in GELT, enhancing learners' communication strategies and capacity for effective English use in global contexts.
A versatile functional interaction between electrically silent KV subunits and KV7 potassium channels
Authors: Renigunta Vijay , Xhaferri Nermina , Shaikh Imran Gousebasha , Schlegel Jonathan , Bisen Rajeshwari , Sanvido Ilaria , Kalpachidou Theodora , Kummer Kai , Oliver Dominik , Leitner Michael G. , Lindner Moritz 
Published: July 2024

AbstractVoltage-gated K+ (KV) channels govern K+ ion flux across cell membranes in response to changes in membrane potential. They are formed by the assembly of four subunits, typically from the same family. Electrically silent KV channels (KVS), however, are unable to conduct currents on their own. It has been assumed that these KVS must obligatorily assemble with subunits from the KV2 family into heterotetrameric channels, thereby giving rise to currents distinct from those of homomeric KV2 channels. Herein, we show that KVS subunits indeed also modulate the activity, biophysical properties and surface expression of recombinant KV7 isoforms in a subunit-specific manner. Employing co-immunoprecipitation, and proximity labelling, we unveil the spatial coexistence of KVS and KV7 within a single protein complex. Electrophysiological experiments further indicate functional interaction and probably heterotetramer formation. Finally, single-cell transcriptomic analyses identify native cell types in which this KVS and KV7 interaction may occur. Our findings demonstrate that KV cross-family interaction is much more versatile than previously thought—possibly serving nature to shape potassium conductance to the needs of individual cell types.
Radiomics combined with clinical and MRI features may provide preoperative evaluation of suboptimal debulking surgery for serous ovarian carcinoma
Authors: Liu Li , Zhang Wenfei , Wang Yudong , Wu Jiangfen , Fan Qianrui , Chen Weidao , Zhou Linyi , Li Juncai , Li Yongmei 
Published: July 2024

Abstract
Purpose
To develop and validate a model for predicting suboptimal debulking surgery (SDS) of serous ovarian carcinoma (SOC) using radiomics method, clinical and MRI features.

Methods
228 patients eligible from institution A (randomly divided into the training and internal validation cohorts) and 45 patients from institution B (external validation cohort) were collected and retrospectively analyzed. All patients underwent abdominal pelvic enhanced MRI scan, including T2-weighted imaging fat-suppressed fast spin-echo (T2FSE), T1-weighted dual-echo magnetic resonance imaging (T1DEI), diffusion weighted imaging (DWI), and T1 with contrast enhancement (T1CE). We extracted, selected and eliminated highly correlated radiomic features for each sequence. Then, Radiomic models were made by each single sequence, dual-sequence (T1CE + T2FSE), and all-sequence, respectively. Univariate and multivariate analyses were performed to screen the clinical and MRI independent predictors. The radiomic model with the highest area under the curve (AUC) was used to combine the independent predictors as a combined model.

Results
The optimal radiomic model was based on dual sequences (T2FSE + T1CE) among the five radiomic models (AUC = 0.720, P < 0.05). Serum carbohydrate antigen 125, the relationship between sigmoid colon/rectum and ovarian mass or mass implanted in Douglas’ pouch, diaphragm nodules, and peritoneum/mesentery nodules were considered independent predictors. The AUC of the radiomic–clinical–radiological model was higher than either the optimal radiomic model or the clinical–radiological model in the training cohort (AUC = 0.908 vs. 0.720/0.854).

Conclusions
The radiomic–clinical–radiological model has an overall algorithm reproducibility and may help create individualized treatment programs and improve the prognosis of patients with SOC.

Graphical abstract
Human Infant Fecal Microbiota Differentially Influences the Mucosal Immune Pathways Upon Influenza Infection in a Humanized Gnotobiotic Pig Model
Authors: Schrock Jennifer , Yan Ming , Dolatyabi Sara , Patil Veerupaxagouda , Yadagiri Ganesh , Renu Sankar , Ramesh Anikethana , Wood Ronna , Hanson Juliette , Yu Zhongtang , Renukaradhya Gourapura J. 
Published: July 2024

AbstractIn this study, we evaluated the impact of human gut microbiota on the immune pathways in the respiratory tract using a gnotobiotic (Gn) piglet model. We humanized piglets with rural and urban infant fecal microbiota (RIFM and UIFM, respectively) and then infected them with a H1N1 swine influenza virus. We analyzed the microbial diversity and structure of the intestinal and respiratory tracts of the piglets before and after the influenza virus infection and measured the viral load and immune responses. We found that the viral load in the upper respiratory tract of UIFM transplanted piglets was higher than their rural cohorts (RIFM), while virus-specific antibody responses were comparable. The relative cytokine gene expression in the tracheobronchial (respiratory tract) and mesenteric (gastrointestinal) lymph nodes, lungs, blood, and spleen of RIFM and UIFM piglets revealed a trend in reciprocal regulation of proinflammatory, innate, and adaptive immune-associated cytokines as well as the frequency of T-helper/memory cells, cytotoxic T cells, and myeloid immune cell subsets. We also observed different phylum-level shifts of the fecal microbiota in response to influenza virus infection between the two piglet groups, suggesting the potential impact of the gut microbiota on the immune responses to influenza virus infection and lung microbiota. In conclusion, Gn piglets humanized with diverse infant fecal microbiota had differential immune regulation, with UIFM favoring the activation of proinflammatory immune mediators following an influenza virus infection compared to their rural RIFM cohorts. Furthermore, Gn piglets can be a useful model in investigating the impact of diverse human microbiota of the gastrointestinal tract, probably also the respiratory tract, on respiratory health and testing specific probiotic- or prebiotic-based therapeutics.
The importance of variance and microsite conditions for growth and hydraulic responses following long-term rewetting in pedunculate oak wood
Authors: Resente Giulia , Di Fabio Alessandro , Scharnweber Tobias , Gillert Alexander , Crivellaro Alan , Anadon-Rosell Alba , Trouillier Mario , Kreyling Juergen , Wilmking Martin 
Published: July 2024

Abstract
Key message
Early rewetting influenced growth variability and hydraulic uniformity in Pedunculate oak wood on disturbed peatland. Long-term study highlighted vessel widening's importance in adapting to water availability changes.

Abstract
Pedunculate oak (Quercus robur L.) is a widely recognized flood-tolerant tree that thrives on fertile and moist soil conditions, such as on or close to peatland ecosystems. In the frame of climate change counteracting policies, rewetting peatland ecosystems is gaining increasing interest, while the ecological consequences are not always clear. Whereas the effect of flooding on wood anatomical traits of pedunculate oak is widely documented, little is known about the effect of permanent rewetting. In this study, we investigated the wood anatomical responses of 12 pedunculate oak trees located on a formerly drained peatland in NE Germany, that experienced flooding and a consequent rewetting. Wood anatomical traits were analyzed via CARROT, a tool that employs the accuracy and efficiency of artificial intelligence to identify tree rings and vessels. Growth anatomical traits (e.g., tree ring width) showed a sudden increase after the rewetting started in 1995, while hydraulic traits (Dh and Ks) displayed a decreasing trend only after the rewetting process was fostered by the opening of an artificial canal in 2004. Variance analysis highlighted subtle changes in the trait’s distribution over time: high soil water content triggered variability in the growth anatomical traits and, simultaneously, homogeneity in the hydraulic traits. Results suggest the relevance of the “vessel widening” mechanisms to develop coping strategies in response to the later stage of the rewetting, and pose relevant insights concerning the importance of specific site conditions for the implementation of rewetting policies in peatlands with presence of pedunculate oak.
Resilience in supply chain risk management in disruptive world: rerouting research directions during and after pandemic
Authors: Madzík Peter , Falát Lukáš , Copuš Lukáš , Čarnogurský Karol 
Published: July 2024

AbstractThe pandemic and a series of subsequent disruptive events fully exposed the vulnerability of supply chains. Research in the field of resilience in supply chain risk management has recorded significant interest across a wide range of academic disciplines. Therefore, there is a need to synthesize, categorize and explain existing and newly emerging research directions, which may represent relevant platforms for developing supply chain concepts in the future. This study addresses this need by providing a bibliometric review of published papers on resilience in supply chain risk management. By analyzing more than 2500 published papers through bibliometric and machine-learning-based methods, we identified ten topics related to risk and resilience of supply chains: Pandemic impacts of food supply chain; Practices for capability and performance; Supplier-related modeling and optimization; System security and critical infrastructure; Production changes; IT in manufacturing process; Sustainability in global economy; Management and business approach; Modeling and design of complex networks; Operational strategies for risk mitigation. By analyzing articles published since 2020, we also identified a change in the direction of research dedicated to supply chain risk and resilience; we identified three other topics that were not recognized as distinct topics prior to 2020—Operational management; strategy; Sustainable production. The results of this study help in understanding the change in the direction of research in the area of risk and resilience of supply chains and thus provide up-to-date information for further research in this dynamically developing area.
Emotion Regulation Flexibility in Adolescents: A Systematic Review from Conceptualization to Methodology
Authors: Haag Ann-Christin , Bagrodia Rohini , Bonanno George A. 
Published: July 2024

AbstractConsiderable attention has been devoted to the concept of flexible emotion regulation, which de-emphasizes the importance of any specific regulatory strategy in favor of the flexible deployment of strategies in response to specific situational challenges. The bulk of research in this area has been conducted on adult samples. Research on emotion regulation flexibility (ERF) in youth has been documented in only a limited number of studies and using various definitions. This systematic review aims to gather and summarize different conceptualizations and methodological approaches of adolescent ERF. We incorporate these findings into a general framework to understand ERF and its role in adolescents’ emotional, behavioral and social functioning. Adhering to the PRISMA guidelines, 11 studies were included in the review. While ERF has been defined in various and inconsistent ways, the included studies utilized conceptualizations from two overarching domains: the regulation of expressed emotion and the repertoire of emotion regulation strategies. Promising approaches and future directions will be highlighted.
A Systematic Literature Review of Strategies Implemented in Extended Education Settings to Address Children’s Mental Health and Wellbeing
Authors: Murray Sarah , March Sonja , Pillay Yosheen , Senyard Emma-Leigh 
Published: July 2024

AbstractMental health and wellbeing problems in middle childhood are increasing worldwide which needs more support than just clinical services. Early intervention has been explored in other settings, but not in extended education care settings such as outside school hours care (OSHC). A systematic literature review was undertaken to determine what interventions have been tested in extended education settings to address or promote emotional, behavioural, or social wellbeing in children, and to assess how effective they have been. A PRISMA guided search found seven peer reviewed articles from an initial pool of 458. Data from the articles were extracted and the mixed method appraisal tool (MMAT) was applied to assess methodological quality of the studies design, data collection, and analyses. The final selections were methodologically heterogeneous with an average MMAT quality rating of 71%. All but one of the interventions were delivered to children in small group settings and were a mix of activities. Studies that trained educators to deliver the interventions were limited and no data were collected for them. The two interventions that trained educators to deliver content to children were seen as promising. This review showed an overall paucity of research examining interventions delivered in extended education settings to improve children’s wellbeing. Given variations in extended education services and the absence of formal qualifications required for educators, further research is needed to understand what interventions may be effective and what role educators could play in such interventions or in supporting children’s wellbeing in extended education.This review protocol was prospectively registered with PROSPERO. Registration ID: CRD42023485541 on 03/12/2023.
Role of Bi/Te co-dopants on the thermoelectric properties of SnSe polycrystals: an experimental and theoretical investigation
Authors: Shankar Manasa R. , Prabhu A. N. , Ashok Anuradha M. , Davis Nithya , Srinivasan Bhuvanesh , Mishra Vikash 
Published: July 2024

AbstractA sustainable solution to the energy crisis may be found in thermoelectric materials and generators, capable of transforming thermal energy into electrical energy or vice versa. SnSe is one of the emerging thermoelectric materials with distinctive properties. The main advantages of this compound are earth-abundant, inexpensive, non-toxic and it is also known for its high thermoelectric performance. Here we prepared Bi/Te co-doped SnSe polycrystals; whereas, Bi and Te are added with different compositions such as (x = 0.0,0.02,0.04,0.06 and y = 0.03) in (Sn1-xBixSe1-YTeY) matrix by using the solid-state reaction method. XRD data confirms the samples belong to the orthorhombic crystal system with the Pnma space group. DFT calculations were used to see structural stability and electronic properties for pure and doped SnSe samples. Temperature-dependent semiconducting behavior of the samples has been demonstrated by electrical resistivity. The Seebeck coefficient, correlated with carrier concentration and mobility, validates the p-type behavior for the pristine samples and the n-type behavior for co-doped samples. The dominant behavior of phonon scattering has been demonstrated by thermal conductivity analysis. After co-doping there is decrement in total thermal conductivity was observed which 1.3 times lower than SnSe. A theoretical calculation was used to validate experimental results to estimate electrical properties, Seebeck coefficient, specific heat capacity, thermal conductivity, and power factor using Quantum espresso code with Boltzmann transport Equation. 4% Bi-doped sample displayed a significant increment in electrical conductivity and an enhanced Seebeck coefficient, which led to the power factor enhancement of approximately 2.0 times in contrast to the pristine sample and enhanced ZT of about 0.055 which is 3.43 times higher than the pristine SnSe.
Graphical abstract