bluuebunny/crossref_metadata_2025_split huggingface dataset:
Supraspinatus Tendon Reconstruction Versus the Bridging Technique in a Rat Model: Histological, Biomechanical, and Functional Outcomes
Authors: Liao Yatao , Wang Jun , Zhou Zhou , Tang Bowen , Li Huaisheng , Mu Yuexi , Nie Mao , Yu Sai , Zhou Binghua 
Published: August 2024

Background: Massive irreparable rotator cuff tears (MIRCTs) are among the most challenging shoulder conditions to treat surgically. Supraspinatus tendon reconstruction (STR) is a recently introduced technique for MIRCTs based on fascia lata-muscle interface healing, which completely differs from the classic bridging technique with fascia lata-tendon interface healing. However, histological and biomechanical comparisons of the fascia-muscle and fascia-tendon interfaces have not been performed. Purpose: To investigate the histological and biomechanical healing of the fascia-bone interface and fascia-muscle interface after chronic MIRCTs in a rat model using different surgical methods. Study Design: Controlled laboratory study. Methods: The authors established a chronic MIRCT model in the right shoulder of rats and then repaired it using the STR or bridging repair technique. Evaluations were performed at 2, 4, 8, and 12 weeks, including histological, imaging, biomechanical, and functional analyses. Results: Both techniques resulted in good fascia-bone interface healing based on the histological results. The STR group had significantly more cartilage formation at 8 and 12 weeks and higher Modified Tendon Maturity Score after 12 weeks at the fascia-bone interface compared with the bridging repair group and formed the typical 4-layered structure. Collagen fibers in the fascia-muscle and fascia-tendon interfaces exhibited normal muscle-tendon interface characteristics at 12 weeks. However, the STR group had more improvement in fatty infiltration compared with the bridging repair group. The ultimate failure load and stiffness did not differ between the STR and bridging repair groups 4 weeks postoperatively in both the fascia-bone interface and supraspinatus muscle-fascia-bone integrity. Movement distance and grasp time were significantly longer in the STR group than in the bridging repair group at 12 weeks and attached the level in the normal control groups. Conclusion: These results suggest that the fascia-muscle interface from the STR technique is histologically and functionally better than the fascia-tendon interface. Moreover, this study provides a theoretical basis for the clinical use of the STR technique. Clinical Relevance: The fascia-muscle interface and fascia-tendon interface were the key points of the STR and bridging techniques, respectively. The fascia-muscle interface is histologically and functionally superior to the bridging technique, and the STR technique might be a better choice for the treatment of MIRCTs.
Mobility and sexually transmitted infections: Exploring intersectional axes of alcohol consumption and risky sexual behavior among Indian men
Authors: Paul Pintu , Chandra Rakesh 
Published: August 2024

Objective Studies in India and other low-income countries find an inconsistent association between mobility/migration and sexually transmitted infections (STIs) among men. This study comprehensively examined the association between mobility and STIs among men in India. It also assessed heterogeneous associations of mobility, alcohol consumption, and risky sexual behavior with STIs using interaction analysis. Methods We utilized a sample of 71,128 sexually active men aged 15-54 years from the 2019-21 National Family Health Survey-5. Binary logistic regression models were employed to study the associations. Results Among the study participants, 16% were mobile and away from home for a month or more in the last 12 months. Around 29% of men reported alcohol consumption and 6% had risky sexual behavior (sexual intercourse with a non-marital/non-cohabitating partner). Regression results suggest that mobility (AOR: 1.41, 95% CI: 1.29-1.55 [short-duration]; AOR: 1.95, 95% CI: 1.77-2.13 [long-duration]) and alcohol consumption (AOR: 1.32, 95% CI: 1.24-1.40) were significantly associated with an increased risk of STIs, even after controlling for socio-demographic covariates. Interaction analysis further reveals that mobile men who consumed alcohol and engaged in risky sexual behavior had a significantly higher likelihood of contracting an STI—twice as high in cases of short-duration mobility and three times higher in cases of long-duration mobility. Conclusion Our study indicates that both short and long-duration mobility are significantly associated with an increased risk of STIs among men. Alcohol consumption and risky sexual behavior further exacerbate the risk of STIs in mobile men. Initiatives for STI/HIV prevention among men must pay particular attention to temporary mobile men for both short and long durations.
Metabolic syndrome risk prediction in an Australian sample with first-episode psychosis using the psychosis metabolic risk calculator: A validation study
Authors: Teasdale Scott B , Ardill-Young Oliver , Morell Rachel , Ward Philip B , Khandaker Golam M , Upthegrove Rachel , Curtis Jackie , Perry Benjamin I 
Published: August 2024

Objective To examine the accuracy and likely clinical usefulness of the Psychosis Metabolic Risk Calculator (PsyMetRiC) in predicting up-to six-year risk of incident metabolic syndrome in an Australian sample of young people with first-episode psychosis. Method We conducted a retrospective study at a secondary care early psychosis treatment service among people aged 16-35 years, extracting relevant data at the time of antipsychotic commencement and between one-to-six-years later. We assessed algorithm accuracy primarily via discrimination (C-statistic), calibration (calibration plots) and clinical usefulness (decision curve analysis). Model updating and recalibration generated a site-specific (Australian) PsyMetRiC version. Results We included 116 people with baseline and follow-up data: 73% male, mean age 20.1 years, mean follow-up 2.6 years, metabolic syndrome prevalence 13%. C-statistics for both partial- (C = 0.71, 95% CI 0.64–0.75) and full-models (C = 0.72, 95% CI 0.65–0.77) were acceptable; however, calibration plots demonstrated consistent under-prediction of risk. Recalibration and updating led to slightly improved C-statistics, greatly improved agreement between observed and predicted risk, and a narrow window of likely clinical usefulness improved significantly. Conclusion An updated and recalibrated PsyMetRiC model, PsyMetRiC-Australia, shows promise. Validation in a large sample is required to confirm its accuracy and clinical usefulness for the Australian population.
Safety, feasibility and efficacy of sonothrombolysis with micro boluses of perfluoropropane as a point of care therapy for patients with acute ST-elevation myocardial infarction
Authors: George Mathen Pratheesh , Krupa Jesu , Samson Nathaniel , Mirza Shohiab , Raja Haynes , Selvaraj Sakthivel , Jose John 
Published: August 2024

Background: Despite advances in timely revascularisation of ST elevation myocardial infarction (STEMI) patients, there are several practical and unavoidable delays. Sonothrombolysis (administered during micro boluses of Perfluoropropane) initiated bedside as a point-of-care therapy during the initial evaluation of the patient may potentially mitigate this by producing early culprit vessel revascularisation. Methods: This was a prospective, single-centre study on hemodynamically stable patients presenting within 12 hours of a first STEMI who consented for study participation. Results: Fifteen patients were recruited over a 1-month period. Eleven were male. Nine patients had anterior wall STEMI and left anterior descending as culprit vessel. There were no significant changes in safety outcomes. Median First Medical Contact (FMC)-Sono time was 12 min (10–15). Median duration of sonothrombolysis was 14 min (12–16). FMC-device time was 97 min (79–128). Six patients had culprit vessel recanalisation before primary percutaneous coronary intervention (PPCI) which was consistent with the reference rates of therapy-associated recanalisation ( p = 0.535). Conclusion: Micro bolus sonothrombolysis maybe safely initiated as a point of care therapy adjunctive to PPCI in hemodynamically stable STEMI patients with reasonable efficacy. Further randomised trials are needed to ascertain its applicability in various geographical and clinical settings.
Examining the Effect of Message Strategies on Peruvian Mothers´ Intentions to Increase Fruit Intake Among Children
Authors: Busse Peter 
Published: August 2024

Background The Peruvian population does not meet the recommended guidelines for daily consumption of fruits and vegetables and, thus, social marketing approaches are needed in order to improve this behavior. Focus of the Article The focus of this study was on changing intentions to engage in a recommended health behavior by experimentally testing one component of a social marketing strategy, namely the effect of messages to motivate mothers to increase the fruit consumption of their children. Research Question What type of messages, either those communicating the advantages of engaging in the recommended behavior or those communicating the norms about the behavior, are better at increasing mothers’ intentions to give 3 daily fruits to their children? Importance to the Social Marketing Field This study identifies methodological steps that can guide future social marketing approaches to test the effect of messages in the area of behavior change. Methods A total of 285 mothers completed an online survey with an experiment built in. Mothers were randomly assigned to one of three conditions: a gain-framed messages condition, a normative messages condition and a no message condition (control condition) and then answered questions about the dependent variables. Results Results showed that exposure to messages communicating information about the advantages of engaging in the behavior increased mothers’ attitudes and intentions to give 3 daily fruits to their children; however, messages communicating information about descriptive norms did not increase mothers’ perceived norms or intentions. Recommendations for Research or Practice Social marketing approaches that address low levels of fruit consumption among children can benefit from message strategies that target mothers and that focus on communicating the advantages of giving more fruits to their children.
Foot and Ankle MRI Findings in Asymptomatic Professional Ballet Dancers
Authors: Katakura Mai , Clark Richard , Lee Justin C. , Mitchell Adam W.M. , Shaw Joseph W. , Tsuchida Anika I. , Jones Mary , Kelly Shane , Calder James D.F. 
Published: August 2024

Background: Previous research in sport populations has demonstrated that abnormal magnetic resonance imaging (MRI) findings may be present in individuals without symptoms or known pathology. Extending this understanding to ballet, particularly in relation to the foot and ankle, is important to guide medical advice given to dancers. Purpose: To assess foot and ankle MRI scans in asymptomatic ballet dancers focusing on bone marrow edema and the posterior ankle and to investigate whether these MRI findings would become symptomatic within 1 year. Study Design: Case series; Level of evidence, 4. Methods: In total, 31 healthy dancers (62 feet/ankles; 15 male and 16 female; age, 26.5 ± 4.3 years) who were dancing in full capacity were recruited from an elite professional ballet company. Orthogonal 3-plane short tau inversion recovery imaging of both feet and ankles was obtained using 3T MRI and the images were reviewed using a standardized evaluation form by 2 musculoskeletal radiologists. Injuries in the company were recorded and positive MRI findings were assessed for correlation with any injuries requiring medical attention during the subsequent 12 months. Results: A total of 51 (82%) of the 62 feet and ankles had ≥1 area of bone marrow edema. The most common locations of bone marrow edema were the talus (n = 41; 66%), followed by first metatarsal (n = 14; 23%). Os trigonum and Stieda process were seen in 5 (8%) and 8 (13%) ankles, respectively. Among them, 2 os trigona showed bone marrow edema. Fluid in the anterior and posterior talocrural joints and the subtalar joint was observed in 48%, 63%, and 63% of these joints, respectively. Fluid around foot and ankle tendons was observed, with the most prevalent being the flexor hallucis longus tendon (n = 13; 21%). Two dancers who had positive findings on their MRI subsequently developed symptoms during the next 12 months. Conclusion: Positive MRI findings are commonplace in the foot and ankle of asymptomatic professional ballet dancers. The majority do not result in the development of symptoms requiring medical attention within 12 months. Careful interpretation of MRI findings with the dancer's clinical picture is required before recommending activity modification or further intervention.
Perceived impacts of a school-based growth mindset programme ‘Mindset Teams’ in Scotland: a qualitative study
Authors: Morgan Kelly , Reed Hayley , Garay Samantha , de Vocht Frank , Murphy Simon 
Published: August 2024

Abstract
Background
Teachers as delivery agents within school-based mindset programmes is a potential intervention strategy for improving pupils’ outcomes. The Mindset Teams programme, utilises teachers as delivery agents, with an aim to improve learning resilience for health and attainment outcomes among schools in Scotland. This study examined the perceived impacts of the programme to develop a programme theory of change and refine an earlier co-produced logic model.

Methods
Across six intervention schools, one-to-one interviews were conducted with teachers (N = 18) and focus groups were conducted with 23 pupils aged 8-11-years. Fourteen stakeholders involved in programme provision, secondary school delivery, funding decisions or policy-related areas also participated in a one-to-one interview. Qualitative data were analysed using thematic analysis with a combined deductive and inductive coding approach.

Results
Themes were identified in relation to impacts on teachers (five themes), pupils (eight themes), and broader outcomes (two themes), with most themes discussed by teachers and wider stakeholders. Across data, findings highlighted the proposed mechanisms by which the programme was intending to produce impacts, largely through increasing teacher knowledge and facilitating a positive school environment. Themes demonstrated the breadth of perceived programme impacts, highlighting both attainment and wellbeing outcomes among pupils.

Conclusions
Findings provide support for Mindset programmes focusing on the development of teachers’ mindsets, highlighting the resultant perceived impacts this can have on both teachers and pupils alike. Future research should seek to capture health and wellbeing measures alongside attainment data to fully explore programme impacts.
Exploring the acceptability, barriers, and facilitators to psychosis screening in the integrated behavioral health primary care setting: a qualitative study
Authors: Savill Mark , Loewy Rachel L , Gobrial Sarah , Kirkpatrick Julianna , Porteus A. Jonathan , Lesh Tyler A , Ragland J. Daniel , Niendam Tara A , Carter Cameron S 
Published: August 2024

Abstract
Background
A longer duration of untreated psychosis (DUP) is associated with poorer treatment outcomes. Screening for psychosis spectrum disorders in the primary care setting could help support the earlier detection and treatment of individuals in need. However, the acceptability of screening for psychosis in this setting as part of routine care is currently unknown.

Methods
We conducted a qualitative interview study with providers and service users who participated in an early psychosis screening program conducted in an integrated behavioral health primary care (IBH-PC) setting. Interviews were recruited from one of eight WellSpace Federally Qualified Health Center IBH-PC clinics in the Sacramento, CA area. Transcripts of the recorded interviews were analyzed using thematic analysis.

Results
In total, 12 providers and eight service users participated in the interviews. Most service user and provider participants were supportive of psychosis screening in an IBH-PC setting, but not as part of the general practitioner consultation due to the brief, non-behavioral health nature of many of the appointments, and the expected low prevalence of psychosis in this population. The support of leadership, adequate training and support, staff turnover, and organizational changes were all seen to impact the successful implementation of the program. Different barriers and facilitators were considered important at each stage of the process from introducing the screening procedures to service users; to determining when, where, and how to screen; and how to effectively manage the referral and post-referral stages.

Conclusions
Despite the additional challenges of screening in an IBH-PC setting relative to secondary mental health services, the process was considered acceptable and feasible to providers and service users. Services that plan to conduct psychosis screening in their clinics need to consider the challenges and their potential solutions to implementation at each stage of the screening process.
Daytime napping and the incidence of Parkinson’s disease: a prospective cohort study with Mendelian randomization
Authors: Lin Fabin , Shi Yisen , Song Wenjing , Weng Yanhong , Zou Xinyang , Chen Xuanjie , Zheng Jiayi , Chen Ke , Ye Qinyong , Wu Xilin , Cai Guoen 
Published: August 2024

Abstract
Background
The causal relationship between daytime napping and the risk of Parkinson’s disease (PD) remains unclear, with prospective studies providing limited evidence. This study investigated the association between daytime napping frequency and duration and PD incidence and explored the causality relationship between this association by conducting Mendelian randomization (MR) analysis.

Methods
This prospective cohort study included 393,302 participants, and accelerometer-measured daytime napping data were available only for 78,141 individuals. Cox proportional hazards regression was used to estimate the association between the daytime napping frequency and duration and the PD risk. The role of the systemic immune-inflammation index (SII) in the association between daytime napping frequency and PD risk was assessed through mediation analyses. Moreover, the causal association between the daytime napping frequency and the PD risk was preliminarily explored by conducting two-sample MR analyses.

Results
The median follow-up duration was 12.18 years. The participants who reported napping sometimes or usually exhibited a significantly higher PD risk than those who never/rarely napped during the day [sometimes: hazard ratio (HR), 1.13; 95% confidence interval (CI), 1.03–1.23; usually: HR, 1.33; 95% CI, 1.14–1.55], and SII played a mediating role in this association. However, the MR analyses did not indicate that the daytime napping frequency and PD risk were significantly associated. The participants napping for over 1 h exhibited a significantly elevated PD risk (HR, 1.54; 95% CI, 1.11–2.16). Moreover, no significant interaction was identified between napping frequency or duration and genetic susceptibility to PD (P for interaction > 0.05).

Conclusions
In this study, increased daytime napping frequency and duration were associated with an increased PD risk, but no causal relationship was observed between napping frequency and PD risk in the MR analysis. Larger GWAS-based cohort studies and MR studies are warranted to explore potential causal relationships.
Novel microwave assisted carboxymethyl-graphene oxide and its hepatoprotective activity
Authors: Tohamy Hebat-Allah S. , Mohamed Fatma El-Zahraa S. , El-Sakhawy Mohamed 
Published: August 2024

AbstractThis study reports a novel, eco-friendly; fast and cost-effective microwave method for synthesizing carboxymethylated graphene oxide (CMGO) from sugarcane residues. Fourier-transform infrared spectroscopy (FTIR) confirmed successful CMGO synthesis through the presence of characteristic peaks at 1567.93 and 1639.29 cm−1 (COONa vibrations) and increased CH2 intensity compared to unmodified graphene oxide (GO). Furthermore, CMGO derived from sugarcane residues demonstrated potential in mitigating the side effects of toxic materials like carbon tetrachloride (CCl4). Treatment with CMGO partially reduced elevated levels of liver enzymes (ALT and AST) and nitrogenous waste products (urea and uric acid) in CCl4-induced liver damage models, suggesting an improvement in liver function despite ongoing cellular damage.This work paves the way for a sustainable and economical approach to produce functionalized graphene oxide with promising biomedical applications in alleviating toxin-induced liver injury.
Graphical abstract
Digitalizing cultural heritage through metaverse applications: challenges, opportunities, and strategies
Authors: Buragohain Dipima , Meng Yahui , Deng Chaoqun , Li Qirui , Chaudhary Sushank 
Published: August 2024

Abstract
Preservation and accessibility of cultural heritage have become essential with the rapid advancements of globalization and modernization endeavors constantly threatening historical artifacts and sites across the world. The advent of the metaverse, with its immersive and interactive capabilities, presents a novel approach to safeguarding and promoting cultural heritage. The current study aims to explore the potential of metaverse applications in digitalizing cultural heritage, encompassing virtual reconstructions, educational outreach, global accessibility, and sustainability. It conducts a systematic literature review using PRISMA guidelines to collect, screen, and evaluate existing research enquiries into investigating current practices and technologies in the digitalization of heritage preservation. The study also conducts case study research to investigate the challenges and opportunities associated with the virtual preservation of tangible and intangible cultural assets, including issues of authenticity, representation, and sustainability. Furthermore, it evaluates the impact of metaverse applications on public engagement and cultural education. The findings provide valuable insights into developing innovative strategies for preserving cultural heritage in the digital age while highlighting best practices and guidelines for optimizing metaverse applications in cultural heritage preservation.