bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sophisticated Conductance Control and Multiple Synapse Functions in TiO2‐Based Multistack‐Layer Crossbar Array Memristor for High‐Performance Neuromorphic Systems
Authors: So Hyojin , Ji Hyeonseung , Kim Sungjun , Kim Sungjoon 
Published: June 2024

AbstractIn this study, oxygen‐rich TiOy and TiOx layers are intentionally designed to have different oxygen compositions, functioning as an overshoot suppression layer (OSL) and oxygen reservoirs. Furthermore, by natural oxidation reactions occurring between the TiOy/TiOx/Al2O3 switching layer and the Pt/Al top electrode, an additional AlOy layer can be induced to act as an additional OSL. The proposed annealing process accelerates the oxidation reaction of AlOy/TiOy OSLs, thereby enhancing the self‐compliance feature of devices. Moreover, the ultrathin AlN serves as an oxygen barrier layer (OBL) that inhibits the movement of oxygen ions at the interface between the Al2O3 layer and the Pt/Ti bottom electrode. The optimized devices are tested by DC sweep and pulses for neuromorphic computing systems. To realize biological synapse characteristics, several key synaptic memory plasticities are proposed. Finally, a 24 × 24 crossbar array based on the 0T‐1R structure, incorporating optimized AlOy/TiOy OSLs and OBL via the annealing process, is characterized. During the electroforming step, all specified target cells (marked with the letters “ESDL”) achieved self‐compliance at low current levels without experiencing hard‐breakdown failures or interference among neighboring cells. The successful array performance is demonstrated by the accurate tuning of target weights.
Intrinsically Safe Lithium Metal Batteries Enabled by Thermo‐Electrochemical Compatible In Situ Polymerized Solid‐State Electrolytes
Authors: Yang Shi‐Jie , Yuan Hong , Yao Nan , Hu Jiang‐Kui , Wang Xi‐Long , Wen Rui , Liu Jia , Huang Jia‐Qi 
Published: June 2024

AbstractIn situ polymerized solid‐state electrolytes have attracted much attention due to high Li‐ion conductivity, conformal interface contact, and low interface resistance, but are plagued by lithium dendrite, interface degradation, and inferior thermal stability, which thereby leads to limited lifespan and severe safety hazards for high‐energy lithium metal batteries (LMBs). Herein, an in situ polymerized electrolyte is proposed by copolymerization of 1,3‐dioxolane with 1,3,5‐tri glycidyl isocyanurate (TGIC) as a cross‐linking agent, which realizes a synergy of battery thermal safety and interface compatibility with Li anode. Functional TGIC enhances the electrolyte polymeric level. The unique carbon‐formation mechanism facilitates flame retardancy and eliminates the battery fire risk. In the meantime, TGIC‐derived inorganic‐rich interphase inhibits interface side reactions and promotes uniform Li plating. Intrinsically safe LMBs with nonflammability and outstanding electrochemical performances under extreme temperatures (130 °C) are achieved. This functional polymer design shows a promising prospect for the development of safe LMBs.
Lightweight Electrolyte Design for Li/Sulfurized Polyacrylonitrile (SPAN) Batteries
Authors: Phan An L. , Nan Bo , Le Phung M. L. , Miao Qiushi , Wu Zhaohui , Le Kha , Chen Fu , Engelhard Mark , Dan Nguyen Thien , Han Kee Sung , Heo Jiyun , Zhang Weiran , Baek Minsung , Xu Jijian , Zhang Xiyue , Liu Ping , Ma Lin , Wang Chunsheng 
Published: June 2024

AbstractSulfurized polyacrylonitrile (SPAN) recently emerges as a promising cathode for high‐energy lithium (Li) metal batteries owing to its high capacity, extended cycle life, and liberty from costly transition metals. As the high capacities of both Li metal and SPAN lead to relatively small electrode weights, the weight and specific energy density of Li/SPAN batteries are particularly sensitive to electrolyte weight, highlighting the importance of minimizing electrolyte density. Besides, the large volume changes of Li metal anode and SPAN cathode require inorganic‐rich interphases that can guarantee intactness and protectivity throughout long cycles. This work addresses these crucial aspects with an electrolyte design where lightweight dibutyl ether (DBE) is used as a diluent for concentrated lithium bis(fluorosulfonyl)imide (LiFSI)‐triethyl phosphate (TEP) solution. The designed electrolyte (d = 1.04 g mL−1) is 40%–50% lighter than conventional localized high‐concentration electrolytes (LHCEs), leading to 12%–20% extra energy density at the cell level. Besides, the use of DBE introduces substantial solvent‐diluent affinity, resulting in a unique solvation structure with strengthened capability to form favorable anion‐derived inorganic‐rich interphases, minimize electrolyte consumption, and improve cell cyclability. The electrolyte also exhibits low volatility and offers good protection to both Li metal anode and SPAN cathode under thermal abuse.
Nickel‐Catalyzed Reductive Amidation of Aryl Sulfonium Salts with Isocyanates for Amide Synthesis via C−S Bond Activation
Authors: Chen Xue , Xu Meng‐Ke , Zhang Xuan‐Qi , Miao Chengping , Chu Xue‐Qiang , Rao Weidong , Xu Hao , Zhou Xiaocong , Shen Zhi‐Liang 
Published: June 2024

AbstractA nickel‐catalyzed reductive amidation of aryl sulfonium salts with isocyanates for amide synthesis via C−S bond cleavage was developed. The reactions proceeded smoothly at ambient temperature in the presence of nickel catalyst and manganese metal in DMF to give a variety of amides in moderate to good yields with wide functional group tolerance.
Data‐Driven Engineering of Phages with Tunable Capsule Tropism for Klebsiella pneumoniae
Authors: Wang Chao , Wang Shiwei , Jing Shisong , Zeng Yuan , Yang Lili , Mu Yongqi , Ding Zixuan , Song Yuqin , Sun Yanmei , Zhang Gang , Wei Dawei , Li Ming , Ma Yingfei , Zhou Haijian , Wu Linhuan , Feng Jie 
Published: June 2024

AbstractKlebsiella pneumoniae, a major clinical pathogen known for causing severe infections, is attracting heightened attention due to its escalating antibiotic resistance. Phages are emerging as a promising alternative to antibiotics; however, their specificity to particular hosts often restricts their use. In this study, a collection of 114 phages is obtained and subjected to analysis against 238 clinical K. pneumoniae strains, revealing a spectrum of lytic behaviors. A correlation between putative tail protein clusters and lysis patterns leads to the discovery of six receptor‐binding protein (RBP) clusters that determine host capsule tropism. Significantly, RBPs with cross‐capsular lysis capabilities are identified. The newly‐identified RBPs provide a toolbox for customizing phages to target diverse capsular types. Building on the toolbox, the engineered phages with altered RBPs successfully shifted and broadened their host capsule tropism, setting the stage for tunable phage that offer a precise and flexible solution to combat K. pneumoniae infections.
Free‐Form Optical Fiber with a Square Mode and Top‐Hat Intensity Distribution
Authors: Kasztelanic Rafal , Nguyen Hue Thi , Pysz Dariusz , Thienpont Hugo , Omatsu Takashige , Buczynski Ryszard 
Published: June 2024

AbstractThe development of bend‐induced effectively single‐mode fiber with a square cross‐section and flat top‐hat intensity distribution is reported using core topology nanostructuring dedicated to femtosecond laser ablation systems. The fiber's core comprises 5419 silica and germanium‐doped silica nanorods with a diameter of 430 nm each arranged into a hexagonal lattice. The distribution of the rods is calculated using in‐house developed code based on the Monte Carlo algorithm to obtain a target shape of mode and intensity distribution. As a proof‐of‐concept, a silica nanostructured fiber with a 24 µm core is developed and verified against the purity of mode guidance, bending, and guiding losses. It is shown that for a wavelength of 1030 nm, the fiber is effectively single‐mode with 96% mode purity when bending with a radius of 20 cm is applied. The fiber has a measured mode area of 360 µm2, numerical aperture of 0.03, and total losses of 0.07 dB m−1.
Host–guest complexation‐induced chirality switching of pillararenes by perylene diimide‐based hexagonal metallacages
Authors: Hou Yali , Mu Chaoqun , Shi Yunzhi , Zhang Zeyuan , Liu Haifei , Zhou Zilin , Ling Sanliang , Shi Bingbing , Duan Xianglong , Yang Cheng , Zhang Mingming 
Published: June 2024

AbstractChirality in confined nanospaces has brought some new insights into chirality transfer, amplification, and chiroptical properties. However, chirality switching, which is a common phenomenon in biological systems, has never been realized in confined environments. Herein, we report a type of hexagonal metallacages that shows good host–guest interactions with ethoxy pillar[5]arene and pillar[6]arene, as confirmed by single‐crystal X‐ray analysis. Importantly, when a chiral pillar[5]arene‐based molecular universal joint (MUJ) is used as the guest, the host–guest complexation would drive the alkyl ring of the MUJ flip from outside to inside the cavity of its pillar[5]arene unit, which enables the configuration change along with the chirality inversion of the MUJ. Moreover, the host–guest complexation facilitates the chirality transfer from guests to hosts, giving circularly polarized luminescence to the system. This study provides a unique metallacage‐pillararene recognition motif for the chirality switching of planar chiral pillararenes, which will promote the construction of host–guest systems with tunable chirality for advanced applications.
Religious participation is associated with fewer dementia diagnoses among Black people in the United States
Authors: Griffith Eric E. , Robbins Paul A. , Ferede Bethlehem T. , Bentley‐Edwards Keisha L. 
Published: June 2024

AbstractIntroductionBlack people had the highest prevalence of Alzheimer's disease and related dementias (ADRD) of any racial/ethnic group in the United States (US) as of 2020. As racial disparities in the prevalence of ADRD are being investigated, more evidence is necessary to determine the pathways and mechanisms that either slow ADRD progression or improve quality of life for those affected. Religion/spirituality (R/S) has been shown to affect health outcomes but has rarely been studied as a possible pathway for reducing ADRD risk. Crucially, Black people also report higher levels of R/S than other racial/ethnic groups in the United States. This research asks if R/S affects ADRD risk among Black adults and if any effects persist after controlling for hypertension.MethodsWe conducted a secondary data analysis drawing from the Health and Retirement Study (HRS), a nationally representative longitudinal dataset with an oversampling of Black adults.ResultsWe used logistic regression analysis to demonstrate how R/S has an ameliorating impact on ADRD risk among Black people, even after controlling for hypertension. Those who never attended religious services had 2.37 higher odds of being diagnosed with ADRD than those who attended more than once a week. Further, as R/S attendance increased, ADRD risk decreased linearly.ConclusionThese findings demonstrate the importance that existing cultural networks (e.g., R/S) can have for reducing ADRD burden for Black people and has important implications for the role of R/S in shaping ADRD symptomatology.
Plasma pTau217 predicts continuous brain amyloid levels in preclinical and early Alzheimer's disease
Authors: Devanarayan Viswanath , Doherty Thomas , Charil Arnaud , Sachdev Pallavi , Ye Yuanqing , Murali Leema Krishna , Llano Daniel A. , Zhou Jin , Reyderman Larisa , Hampel Harald , Kramer Lynn D. , Dhadda Shobha , Irizarry Michael C. 
Published: June 2024

AbstractBACKGROUNDThis study investigated the potential of phosphorylated plasma Tau217 ratio (pTau217R) and plasma amyloid beta (Aβ) 42/Aβ40 in predicting brain amyloid levels measured by positron emission tomography (PET) Centiloid (CL) for Alzheimer's disease (AD) staging and screening.METHODSQuantification of plasma pTau217R and Aβ42/Aβ40 employed immunoprecipitation‐mass spectrometry. CL prediction models were developed on a cohort of 904 cognitively unimpaired, preclinical and early AD subjects and validated on two independent cohorts.RESULTSModels integrating pTau217R outperformed Aβ42/Aβ40 alone, predicting amyloid levels up to 89.1 CL. High area under the receiver operating characteristic curve (AUROC) values (89.3% to 94.7%) were observed across a broad CL range (15 to 90). Utilizing pTau217R‐based models for low amyloid levels reduced PET scans by 70.5% to 78.6%.DISCUSSIONpTau217R effectively predicts brain amyloid levels, surpassing cerebrospinal fluid Aβ42/Aβ40's range. Combining it with plasma Aβ42/Aβ40 enhances sensitivity for low amyloid detection, reducing unnecessary PET scans and expanding clinical utility.CLINICALTRIALS.GOV IDENTIFIERSNCT02956486 (MissionAD1), NCT03036280 (MissionAD2), NCT04468659 (AHEAD3‐45), NCT03887455 (ClarityAD)Highlights
Phosphorylated plasma Tau217 ratio (pTau217R) effectively predicts amyloid‐PET Centiloid (CL) across a broad spectrum.
Integrating pTau217R with Aβ42/Aβ40 extends the CL prediction upper limit to 89.1 CL.
Combined model predicts amyloid status with high accuracy, especially in cognitively unimpaired individuals.
This model identifies subjects above or below various CL thresholds with high accuracy.
pTau217R‐based models significantly reduce PET scans by up to 78.6% for screening out individuals with no/low amyloid.
The Dependence of Solid Electrolyte Interphase on the Crystal Facet of Current Collector in Li Metal Battery
Authors: Hao Zhimeng , Li Geng , Zheng Chunyu , Liu Xinyi , Wu Shuang , Li Haixia , Zhang Kai , Yan Zhenhua , Chen Jun 
Published: June 2024

AbstractThe continuous electrolyte decomposition and uncontrolled dendrite growth caused by the unstable solid electrolyte interphase (SEI) have largely hindered the development of Li metal batteries. Here, we demonstrate that tuning the facet of current collector can regulate the composition of SEI and the subsequent Li deposition behavior using single‐crystal Cu foils as an ideal platform. The theoretical and experimental studies reveal that the (100) facet of Cu possesses strong adsorption to anions, guiding more anions to participate preferentially in the inner Helmholtz plane and further promoting the formation of the stable inorganic‐rich SEI. Consequently, the single‐crystal Cu foils with a single [100] orientation (s‐Cu(100)) achieve the dendrite‐free Li deposition with enhanced Li plating/stripping reversibility. Moreover, the Li anode deposited on s‐Cu(100) can stabilize the operation of an Ah‐level pouch cell (350 Wh kg−1) with a low negative/positive capacity ratio (~2) and lean electrolyte (2.4 g Ah−1) for 150 cycles. Impressively, this strategy demonstrates universality in a series of electrolytes employed different anions. This work provides new insights into the correlation between the SEI and current collector, opening a universal avenue towards high‐performance Li metal batteries.
Novel Self‐Assembling Supramolecular Phenanthro[9,10‐a]phenazine Discotic Liquid Crystals: Synthesis, Characterization and Charge Transport Studies
Authors: Patra Alakananda , Shah Asmita , Singh Dharmendra Pratap , Roy Arun , Kumar Sandeep 
Published: June 2024

AbstractThe incorporation of heteroatoms in the chemical structure of organic molecules has been identified as analogous to the doping process adopted in silicon semiconductors to influence the nature of charge carriers. This strategy has been an eye‐opener for material chemists in synthesizing new materials for optoelectronic applications. Phenanthro[9,10‐a]phenazine‐based mesogens have been synthesized via a cyclo‐condensation pathway involving triphenylene‐based diketone and o‐phenyl diamines. The incorporation of phenazine moiety as discussed in this paper, alters the symmetric nature of the triphenylene. The phenanthro[9,10‐a]phenazine‐based mesogens exhibit hole mobility in the order of 10−4 cm2/Vs as measured by the space‐charge limited current (SCLC) technique. The current density in the SCLC device increases with increasing temperature which indicates that the charge transport is associated with the thermally activated hopping process. This report attempts to elucidate the self‐organization of asymmetric phenanthro[9,10‐a] phenazine in the supramolecular liquid crystalline state and their potential for the fabrication of high‐temperature optoelectronic devices. However, the low charge carrier mobility can be one of the challenges for device performance.
Influence of Configurational Isomerism of Pyridine π Bridge in Donor‐π Bridge‐Acceptor Type Covalent Triazine Frameworks on The Photocatalytic Performance
Authors: Xiong Ji , Li Xiangyu , Chen Minghui , Shi Quan , Jiang Yu , Feng Yaqing , Zhang Bao 
Published: June 2024

AbstractCovalent triazine frameworks (CTFs) involving a donor‐π bridge‐acceptor (D‐π‐A) structure are considered one of the most promising photocatalytic materials, in which the π bridge is known to play an important role in influencing the photocatalytic performance. So far, much effort has been directed at the designing of the different π bridge structure to facilitate the photo‐induced charge separation. However, the orientation of the π bridge units (configurational isomerism) has not been considered. In this paper, a pair of pyridine‐bridged D‐π‐A type CTFs, named TFA‐P1‐CTF and TFA‐P2‐CTF, were designed to investigate how the orientation of the π bridge would influence their performance in the photocatalytic oxidation of olefins into carbonyl compounds. Interestingly, due to the superior charge separation capability, TFA‐P2‐CTF was found to be able to catalyze the reaction more efficiently than TFA‐P1‐CTF. Our study eventually provided a guide for the design of D‐π‐A type CTFs as high‐performance photocatalytic materials via tuning the configurational isomerism of the π bridge unit for use in chemical transformations.
Olivine NaMn0.66Fe0.34PO4 as a Cathode Material for Advanced Sodium Ion Batteries
Authors: Ouaneche Tassadit , Stievano Lorenzo , Monconduit Laure , Guéry Claude , Sougrati Moulay Tahar , Recham Nadir 
Published: June 2024

AbstractSodium‐ion batteries continue to rise in the energy storage landscape, their increasing adoption being driven by factors such as cost‐effectiveness and sustainability. As a consequence, there is a growing emphasis on the development of new electrode materials. Among these, olivine phosphates emerge as a promising family of cathode materials. However, viable synthesis routes are still lacking. In this study, cathode materials of olivine NaMn1‐xFexPO4 (x=0.34 and 1) were prepared by directly sodiating Mn1‐xFexPO4 through a solid‐state process at 300 °C. X‐ray diffraction, Mössbauer spectroscopy and electrochemical measurements were employed to study their structural and electrochemical features. NaMn0.66Fe0.34PO4 exhibits two pseudo‐plateaus profile with an average potential of ~3.2 V vs. Na+/Na0 with a reversible capacity reaching 75 mAh/g at C/20 via a monophasic (de)intercalation mechanism. In parallel, the intermediate composition Na0.5Mn0.66Fe0.34PO4 could be prepared via the solid‐state reaction of NaMn0.66Fe0.34PO4 and Mn0.66Fe0.34PO4. Such a solvent‐free sodiation process not only provides a simplified preparation of NMFP, but also offers easy scalability compared to the more laborious electrochemical sodiation route, making it an interesting prospect for future industrialization. Finally, this research confirms that the olivine NMFP is indeed an attractive candidate as a cathode material for SIBs.
Enhancing Voltage Output in Polyanion‐Type Cathode Materials for Sodium Ion Batteries
Authors: Liu Aifang , Lu Suwan , Wu Xiaodong 
Published: June 2024

AbstractSodium‐ion batteries (SIBs) are promising in several aspects due to their many advantages over lithium‐ion batteries. Among SIB's several outstanding attributes, its low cost, resource abundance, and potential safety make it suitable for large‐scale energy storage systems (ESS). Among the potential cathode materials, poly‐anionic cathode materials could be a better choice for their stability and safety in comparison to layered transition metal oxides and Prussian blue analogues (PBA). However, on the other hand, the conductivity as well as the available capacity of the polyanion compounds are still poor, which limits their applications; moreover, some polyanion cathode operate at low voltage, which reduces the energy density and raises the cost of the battery system. We here try to summarize the recent progress of polyanion compounds as cathode materials for SIB. These compounds are categorized based on the metal redox couple, including V‐, Cr‐, Mn‐, Fe‐, Co‐, and Ni‐polyanion compounds. Our attention is specifically drawn to properties such as reversible redox voltage, capacity, cycling stability, and sodium storage mechanisms. We also discuss the challenges and potential development strategies for the future.
Polyethyleneimine incorporated hydroxyapatite for improved colloidal stability
Authors: Choi Hyebin , An Jaun , Lee Keunyoung , Kwon Ki‐Young 
Published: June 2024

AbstractWe report on the preparation of a polyethyleneimine‐incorporated hydroxyapatite (PEI‐HAP) and its enhanced colloidal stability. Three PEI‐HAPs having different amine contents are synthesized by hydrothermal treatment (200 °C) of the HAP prepared at room temperature (rt‐HAP). The crystallinity of PEI‐HAP is improved compared to rt‐HAP due to the heat treatment. In addition, the size of PEI‐HAP (50.4 nm) increased compared to rt‐HAP (32.1 nm) after heat treatment. However, the presence (or concentration) of PEI has little effect on the crystallinity and size of the samples. Ninhydrin test indicates the presence of amine group in PEI‐HAPs. XPS experiments verified that maximum amine content amounts to 2.81%. As the amount of amine increases, the zeta potential is changed from −22.6 to +31.7 mV due to the adsorption of PEI on HAP surface. Consequently, the sample having high positive valuable zeta potential of +31.7 mV exhibits colloidal stability of more than 6 h.
Morin reverses P‐glycoprotein‐mediated multidrug‐resistance in KBChR‐8‐5 cancer cell lines
Authors: Zhao Yan , Xu Sanhui , Hao Weiting , Fu Yongqing 
Published: June 2024

AbstractMultidrug resistance (MDR) during clinical chemotherapy for cancer has been considered a major obstacle to treatment efficacy. The involvement of adenosine triphosphate‐binding cassette (ABC) transporters in the MDR mechanism significantly reduces the efficacy of chemotherapeutics. This study investigates the potential of morin, a dietary bioflavonoid, to overcome colchicine resistance in KBChR‐8‐5 MDR cells. The P‐gp inhibitory activity by morin was measured by calcein‐AM drug efflux assay. Western blot analysis was employed to evaluate P‐gp messenger RNA and protein expressions following morin treatment. Flow cytometry analysis and acridine orange/ethidium bromide fluorescence staining were utilised to investigate the induction of apoptosis and cell cycle arrest upon treatment with morin and paclitaxel in combination. Additionally, polymerase chain reaction (PCR) array analysis was conducted to study the gene expression profiles related to MDR, apoptosis and cell cycle arrest during treatment with morin, paclitaxel or their combination. Morin exhibited a strong binding interaction with human P‐gp. This was corroborated by drug efflux assays, which showed a reduction in P‐gp efflux function with increasing morin concentration. Furthermore, morin and paclitaxel combination potentiated the induction of apoptosis and G2/M phase cell cycle arrest. Morin treatment significantly downregulated the gene expression of ABCB1 and P‐gp membrane expressions in MDR cells. Additionally, PCR array gene expression analysis revealed that the combination treatment with morin and paclitaxel upregulated proapoptotic and cell cycle arrest genes while downregulating ABCB1 gene and antiapoptotic genes. Thus, morin effectively reversed paclitaxel resistance in KBChR‐8‐5 drug‐resistant cancer cells and concluded that morin resensitized the paclitaxel resistance in KBChR8‐5 drug‐resistant cancer cells.