bluuebunny/crossref_metadata_2025_split huggingface dataset:
CARACTERIZAÇÃO LITOESTRATIGRÁFICA E GEOTÉCNICA E CORRELAÇÕES COM A OCORRÊNCIA DE PROCESSOS DE MOVIMENTO DE MASSA EM TALUDE DA FORMAÇÃO BARREIRAS (CARIACICA-ES)
Authors: Bricalli Luiza Leonardi 
Published: July 2015

Este estudo tem como objetivo descrever e analisar os aspectos litoestratigráficos e geotécnicos, afim de correlacioná-los à ocorrência do processo de movimento de massa (deslizamento) no talude da Formação Barreiras (Cariacica-ES). A base metodológica utilizada foi:execução de Sondagem à Percussão Standard Penetration Test (SPT); análises das camadas estratigráficas; elaboração de perfis geológicos; realização de análises de granulometria, compactação, limite de liquidez e de plasticidade e cisalhamento. Foi possível estabelecer os fatores de Instabilidade do talude e identificar a superfície de Ruptura do Deslizamento, identificando 2 (dois) níveis litoestratigráficos:i)um conjunto de camadas de material fino (argilito),em sua porção superior e; ii) um conjunto de camadas de material mais grosseiro (arenitos). Ambos os pacotes apresentam fatores de segurança abaixo de 1.
Un bagage linguistique diversifié comme capital humain : esquisse d’un (nouveau) rapport aux langues en Acadie
Authors: Arrighi Laurence 
Published: July 2015

Au Canada, les instances gouvernementales et associatives produisent un discours sur les questions linguistiques qui est adapté aux nouveaux modes de production et de gouvernance, façonnés par les transformations économiques, politiques et sociales contemporaines. Au sein des communautés francophones minoritaires, l’accent est mis sur les langues comme capital et outil de développement économique. Tenir les habiletés langagières de ces communautés comme un atout fait partie intégrante de l’« espace discursif francophone » contemporain (Heller et Labrie, 2003). Dans cet article, je montre comment les transformations sociales et discursives se manifestent et alimentent les prises de parole et de position des individus. Plus précisément, j’explore le pendant individuel du discours sur la rentabilisation du capital linguistique comme outil de développement personnel. Je propose essentiellement d’illustrer, dans des prises de parole d’Acadiens, l’une des caractéristiques majeures de la modernité avancée, en l’occurrence l’application des principes et des valeurs du néolibéralisme à la vie sociale et personnelle des individus.
Regulation of biofilm formation and cellular buoyancy through modulating intracellular cyclic di‐GMP levels in engineered cyanobacteria
Authors: Agostoni Marco , Waters Christopher M. , Montgomery Beronda L. 
Published: July 2015

ABSTRACTThe second messenger cyclic dimeric (3′→5′) GMP (cyclic di‐GMP or c‐di‐GMP) has been implicated in the transition between motile and sessile lifestyles in bacteria. In this study, we demonstrate that biofilm formation, cellular aggregation or flocculation, and cellular buoyancy are under the control of c‐di‐GMP in Synechocystis sp. PCC 6803 (Synechocystis) and Fremyella diplosiphon. Synechocystis is a unicellular cyanobacterium and displays lower levels of c‐di‐GMP; F. diplosiphon is filamentous and displays higher intracellular c‐di‐GMP levels. We transformed Synechocystis and F. diplosiphon with a plasmid for constitutive expression of genes encoding diguanylate cylase (DGC) and phosphodiesterase (PDE) proteins from Vibrio cholerae or Escherichia coli, respectively. These engineered strains allowed us to modulate intracellular c‐di‐GMP levels. Biofilm formation and cellular deposition were induced in the DGC‐expressing Synechocystis strain which exhibited high intracellular levels of c‐di‐GMP; whereas strains expressing PDE in Synechocystis and F. diplosiphon to drive low intracellular levels of c‐di‐GMP exhibited enhanced cellular buoyancy. In addition, the PDE‐expressing F. diplosiphon strain showed elevated chlorophyll levels. These results imply roles for coordinating c‐di‐GMP homeostasis in regulating native cyanobacterial phenotypes. Engineering exogenous DGC or PDE proteins to regulate intracellular c‐di‐GMP levels represents an effective tool for uncovering cryptic phenotypes or modulating phenotypes in cyanobacteria for practical applications in biotechnology applicable in photobioreactors and in green biotechnologies, such as energy‐efficient harvesting of cellular biomass or the treatment of metal‐containing wastewaters. Biotechnol. Bioeng. 2016;113: 311–319. © 2015 Wiley Periodicals, Inc.
Catheter-Associated Urinary Tract Infections in Intensive Care Unit Patients
Authors: Tedja Rudy , Wentink Jean , O’Horo John C , Thompson Rodney , Sampathkumar Priya 
Published: July 2015

OBJECTIVETo delineate the epidemiology of catheter-associated urinary tract infections (CAUTIs) and to better understand the value of urine cultures for evaluation of fever in the intensive care unit (ICU) settingDESIGNTwo-year retrospective review (2012–2013)SETTINGA single tertiary center with 1,200 hospital beds and 158 adult ICU bedsPATIENTSICU patients with a CAUTI eventMETHODSThe cohort was identified from a prospective infection prevention database. Charts were reviewed to characterize the patients. CAUTI rates and device utilization ratio (DUR) were calculated. Clinical outcomes were recorded.RESULTSA total of 105 CAUTIs were identified using the National Health and Safety Network (NHSN) definition. Fever was the primary indication for obtaining urine culture in 102 patients (97%). Of these 105 patients, 51 (51%) had an alternative infection to explain the fever, with pneumonia (55%) being the most common followed by bloodstream infection (22%). A total of 18 patients (18%) had fever due to noninfectious cause, and 32 patients (32%) had no alternative explanation. Of these, 66% received appropriate empiric antimicrobial therapy, but no targeted therapy changes were made based on urine culture results. The other 34% did not receive antimicrobial therapy at all. Only 6% of all CAUTIs resulted in blood cultures positive for the same organism within 2 days. The urinary tract was not definitely established as the source of bloodstream infection.CONCLUSIONSUrine cultures obtained for evaluation of fever form the basis for identification of CAUTIs in the ICU. However, most patients with CAUTIs are eventually found to have alternative explanations for fever. CAUTI is associated with a low complication rate.Infect. Control Hosp. Epidemiol. 2015;36(11):1330–1334
Comparison of VivaSight double‐lumen tube with a conventional double‐lumen tube in adult patients undergoing video‐assisted thoracoscopic surgery
Authors: Levy‐Faber D. , Malyanker Y. , Nir R.‐R. , Best L. A. , Barak M. 
Published: July 2015

SummaryThe efficiency of a double‐lumen tube depends on its position in the airways, which can be verified by fibreoptic bronchoscopy. The VivaSight DL is a single‐use double‐lumen tube with a camera embedded in the tube's right side. The view from the camera appears continuously on a monitor. In this prospective study of 71 adult patients, we compared intubation times using either the VivaSight DL or a conventional double‐lumen tube. Median (IQR [range]) duration of intubation with visual confirmation of tube position was significantly reduced using the VivaSight DL compared with the conventional double‐lumen tube (51 (42–60 [35–118]) s vs 264 (233–325 [160–490]) s, respectively, p < 0.0001). None of the patients allocated to the VivaSight DL required fibreoptic bronchoscopy during intubation or surgery. The VivaSight DL enables significantly more rapid intubation compared with the conventional double‐lumen tube.
Real‐Time PCR and Droplet Digital PCR: two techniques for detection of the JAK2V617F mutation in Philadelphia‐negative chronic myeloproliferative neoplasms
Authors: Fontanelli G. , Baratè C. , Ciabatti E. , Guerrini F. , Grassi S. , Del Re M. , Morganti R. , Petrini I. , Arici R. , Barsotti S. , Metelli M. R. , Danesi R. , Galimberti S. 
Published: July 2015

SummaryIntroductionPhiladelphia‐negative chronic myeloproliferative neoplasms (MPNs) are clonal disorders that present JAK2V617F mutation in 50–95% of cases. The main objective of this study was the comparison of two PCR methods, real‐time (qPCR) and droplet digital PCR (DD‐PCR) for detection of the JAK2V617F mutation, to assess analytic sensitivity, specificity, and feasibility of the two methods.MethodsNinety‐nine patients with MPN of 225 presenting the JAK2V617F mutation by qPCR have been evaluated by DD‐PCR also.ResultsWe demonstrated an absolute concordance in terms of specificity between the two methods, DD‐PCR showing a higher sensitivity (half a log higher than qPCR). As expected, a progressive increase of mutant allele burden was observed from essential thrombocythemia (ET) to polycythemia vera (PV) and primary myelofibrosis (PMF) to secondary myelofibrosis (SMF).ConclusionIn conclusion, our study showed that DD‐PCR could represent a new and promising technological evolution for detection of JAK2 mutation in MPNs.
Clinicopathological characteristics of immunoglobulin G4-related sialadenitis
Authors: Li Wei , Chen Yan , Sun Zhi-Peng , Cai Zhi-Gang , Li Tong-Tong , Zhang Lei , Huang Min-Xian , Hua Hong , Li Mei , Hong Xia , Su Jia-Zeng , Zhang Zhu-Yan , Liu Yan-Ying , He Jing , Li Zhan-Guo , Gao Yan , Yu Guang-Yan 
Published: July 2015

Abstract
Introduction
Immunoglobulin G4-related disease (IgG4-RD) is a newly recognized fibro-inflammatory condition. Forty-two cases with immunoglobulin G4-related sialadenitis (IgG4-RS) confirmed by histopathological and immunohistochemical assessment were studied to clarify the clinicopathologic characteristics of the salivary glands involved in IgG4-RS, especially the relationship between the histopathologic features and function of salivary glands or serum levels of IgG4.

Methods
Clinical, serologic, imaging and histopathological data of these cases were analyzed. CT volumes of submandibular, parotid, and lacrimal glands were calculated. The saliva flow rate was measured. Scintigraphy with 99mTc-pertechnetate was undertaken in 31 cases, and the concentration index (CI) and secretion index (SI) was calculated. Relationships between fibrosis severity and salivary gland function or serum IgG4 levels were analyzed.

Results
The first symptom was swelling of bilateral submandibular or lacrimal glands. Physical examination showed multiple bilateral major salivary glands (including sublingual and accessory parotid glands) and lacrimal glands were enlarged in IgG4 RS. Multiple enlarged cervical lymph nodes were noted in 30 patients. Saliva flow at rest was lower than normal in 34 cases; stimulated saliva flow was lower than normal in 15 cases. Secretory function was reduced more severely in the submandibular glands than in the parotid glands. Serum levels of IgG4 were elevated in 95.2% of cases and 78.6% patients had increased IgE levels. Serum IgG4 level was higher and saliva secretion lower as glandular fibrosis increased.

Conclusions
Prominent changes in the morphology, histology, immunohistochemistry and secretion of the major salivary glands of IgG4-RS patients were accompanied by involvement of the lacrimal glands and cervical lymph nodes. Elevated IgE, allergic history, eosinophil infiltration suggest allergic reactions as a potential pathogenesis of IgG4-RS. Severity of glandular fibrosis correlated with salivary function and serum levels of IgG4.
Cinética de crescimento de levedura em mosto de cagaita para produção de bebida fermentada
Authors: Lopes Ana Cláudia Alencar , Pinto Ismael De Oliveira , Souza Clovis Maurilio de , Cangussu Alex Sander Rodrigues , Oliveira Mara Elisa Soares de 
Published: July 2015

<p><strong>Resumo: </strong>Objetivo deste trabalho foi realizar o estudo inicial da cinética de crescimento de levedura para servir como base para futuros estudos visando determinar a potencialidade do mosto de cagaita como fonte de substrato na fermentação alcoólica de S. cerevisiae visando a produção de bebida fermentada. Os frutos foram coletados na região sul do estado de Tocantins e após clarificação foi realizado a inoculação com concentração inicial de 1,8 x 103 Células por ml. Os parâmetros analisados foram, pH, teor de sólidos solúveis e densidade ótica a 550nm e taxa de crescimento celular. Como resultados observamos que o TSS inicial apresenta valor bem acima do encontrado em outras frutas como cajá, melancia e caju, os valores de pH inicial do mosto encontra-se abaixo da maioria dos dados da literatura e abaixo do considerado ideal para o crescimento de leveduras e ainda que a velocidade de crescimento abaixo da maioria dos dados disponíveis na literatura são possivelmente decorrentes de fatores nutricionais ou em relação à cepa utilizada.</p><p align="center"><strong><em><br /></em></strong></p><p align="center"><strong><em>Kinetics of growth of yeast in wort of cagaita for production of fermented beverage</em></strong></p><p> </p><pre><strong>Abstract: </strong>The objective this work was the initial study of growth kinetics of yeast to serve as a basis for future studies to determine the potential of the wort cagaita as a source of substrate in the fermentation of Saccharomyces cerevisiae aimed at producing of fermented drink. Fruits were collected in the southern state of Tocantins and after clarification was conducted inoculation with initial concentration of 1.8 x 103 cells per ml. The analyzed parameters were pH, soluble solids, and optical density at 550nm and cell growth rate. As a result we observe that the initial TSS presented value well above that found in other fruits like cajá, watermelon and cashew, the values of initial pH of the wort is below the majority of the literature data and below the considered ideal for the growth of yeasts and although the growth rate was lower than most of the data available in the literature is possibly arising from nutritional factors or relative to the strain used.</pre><p><span style="font-size: 12.0pt; line-height: 115%; font-family: 'Times New Roman','serif'; mso-fareast-font-family: Calibri; mso-fareast-theme-font: minor-latin; mso-ansi-language: PT-BR; mso-fareast-language: EN-US; mso-bidi-language: AR-SA;"><br /></span></p>
Increasing background seismicity and dynamic triggering behaviors with nearby mining activities around Fangshan Pluton in Beijing, China
Authors: Wang Weijun , Meng Xiaofeng , Peng Zhigang , Chen Qi‐Fu , Liu Ning 
Published: July 2015

AbstractDynamic triggering in western Fangshan Pluton, Beijing, China, has been repeatedly identified, but previous studies are limited by sparse seismic station coverage. Here we systematically analyze continuous waveforms recorded by both permanent stations and a temporary seismic network 40 days before and after the 11 March 2011 Mw 9.1 Tohoku‐Oki and the 14 April 2012 Mw 8.6 Indian Ocean earthquakes. We first build a template database using a short‐term average to long‐term average method. Next, we apply the matched filter technique that cross correlates the template waveforms with continuous data to detect additional seismic events. Overall, we detect 1956 and 950 seismic events around the Tohoku‐Oki and Indian Ocean main shocks, respectively. Most detected events are shallow (<5 km) and clustered at Beiling Syncline in western Fangshan Pluton, which is adjacent to a running coalmine. Seven and 10 events are detected during the large‐amplitude surface waves of the two main shocks, respectively, but no similar burst is detected following their major foreshock and aftershocks. Multiple statistical tests indicate that the short‐term bursts after the two main shocks are dynamically triggered. We suggest that mining‐related activities may perturb the subsurface stress conditions and hence make the region more susceptible for dynamic triggering than other places.
The hysteresis response of soil CO2 concentration and soil respiration to soil temperature
Authors: Zhang Quan , Katul Gabriel G. , Oren Ram , Daly Edoardo , Manzoni Stefano , Yang Dawen 
Published: July 2015

AbstractDiurnal hysteresis between soil temperature (Ts) and both CO2 concentration ([CO2]) and soil respiration rate (Rs) were reported across different field experiments. However, the causes of these hysteresis patterns remain a subject of debate, with biotic and abiotic factors both invoked as explanations. To address these issues, a CO2 gas transport model is developed by combining a layer‐wise mass conservation equation for subsurface gas phase CO2, Fickian diffusion for gas transfer, and a CO2 source term that depends on soil temperature, moisture, and photosynthetic rate. Using this model, a hierarchy of numerical experiments were employed to disentangle the causes of the hysteretic [CO2]‐Ts and CO2 flux Ts (i.e., F‐Ts) relations. Model results show that gas transport alone can introduce both [CO2]‐Ts and F‐Ts hystereses and also confirm prior findings that heat flow in soils lead to [CO2] and F being out of phase with Ts, thereby providing another reason for the occurrence of both hystereses. The area (Ahys) of the [CO2]‐Ts hysteresis near the surface increases, while the Ahys of the Rs‐Ts hysteresis decreases as soils become wetter. Moreover, a time‐lagged carbon input from photosynthesis deformed the [CO2]‐Ts and Rs‐Ts patterns, causing a change in the loop direction from counterclockwise to clockwise with decreasing time lag. An asymmetric 8‐shaped pattern emerged as the transition state between the two loop directions. Tracing the pattern and direction of the hysteretic [CO2]‐Ts and Rs‐Ts relations can provide new ways to fingerprint the effects of photosynthesis stimulation on soil microbial activity and detect time lags between rhizospheric respiration and photosynthesis.
Morphological and Structural Evolutions of Metal–Organic Framework Particles from Amorphous Spheres to Crystalline Hexagonal Rods
Authors: Lee Hee Jung , We Junghun , Kim Jun Oh , Kim Dooyoung , Cha Wonhee , Lee Eunji , Sohn Jeungwon , Oh Moonhyun 
Published: July 2015

AbstractCompositions as well as morphologies and structures of particles are vital factors that define their properties and applications. However, the morphology and structure changes associated with the composition change of metal–organic frameworks (MOFs) are barely studied. Herein, we report the morphology and structure changes of MOF particles associated with the ratio of two organic linkers incorporated within MOF particles, when they are constructed from the reactions of In(NO3)3 in the presence of isophthalic acid (H2IPA) and/or 1,4‐benzenedicarboxylic acid (H2BDC). Two tendencies—the tendency of BDC and In3+ to form porous crystalline hexagonal rods, and the tendency of IPA and In3+ to form non‐porous amorphous spherical particles—compete during the formation of MOF particles. Eventually, the incorporated ratio of BDC and IPA within the MOF particles, and thus their morphology and porosity, are controlled by altering the relative amounts of H2BDC and H2IPA used during the reactions.
Heregulin and HER3 are prognostic biomarkers in oropharyngeal squamous cell carcinoma
Authors: Qian Guoqing , Jiang Ning , Wang Dongsheng , Newman Scott , Kim Sungjin , Chen Zhengjia , Garcia Gabriela , MacBeath Gavin , Shin Dong M. , Khuri Fadlo R. , Chen Zhuo G. , Saba Nabil F. 
Published: July 2015

BACKGROUNDAlthough heregulin and human epidermal growth factor receptor 3 (HER3) are frequently expressed at high levels in patients with head and neck cancer, their prognostic value remains unclear. The authors explored the prognostic significance of heregulin/HER3 expression in patients with oropharyngeal squamous cell carcinoma (OPSCC), taking into account other HER family members as well as p16 status.METHODSNinety‐six primary tumor specimens from patients with OPSCC were retrospectively collected and analyzed for heregulin messenger RNA (mRNA) using in situ hybridization and for HER3, epidermal growth factor receptor, and human epidermal growth factor receptor 2 (HER2) using quantitative immunohistochemistry. Heregulin and HER3 mRNA levels were also examined among different tumor types using The Cancer Genome Atlas database.RESULTSHigh heregulin mRNA (> the median) correlated significantly with poor overall survival (OS) (hazard ratio [HR], 8.48; 95% confidence interval [95% CI], 2.17‐33.17 [P =.002]) but not disease‐free survival (HR, 1.52; 95% CI, 0.64‐3.65 [P =.341]) in patients with OPSCC. Heregulin mRNA correlated negatively with OS in both patients with p16‐positive (P =.049) and p16‐negative (P =.091) OPSCC on univariate analysis. High HER3 (> the median) also correlated with poor OS (HR, 4.68; 95% CI, 1.47‐14.90 [P =.009]) on multivariate analysis. Epidermal growth factor receptor levels independently correlated with disease‐free survival (P =.025) and inversely correlated with p16 status (P =.012). In addition, The Cancer Genome Atlas data demonstrated that head and neck squamous cell carcinoma exhibits higher heregulin expression compared with other solid tumor types examined.CONCLUSIONSHigh heregulin mRNA and high HER3 protein levels were found to independently correlate with poor OS in patients with OPSCC. These data support targeting HER3 in patients with heregulin‐high OPSCC and warrant further clinical investigation. Cancer 2015;121:3600–3611. © 2015 American Cancer Society.
A Restart Control Method for Position Sensorless PMSM Drive Systems Without Potential Transformer for Railway Vehicle Traction
Authors: Taniguchi Shun , Yasui Kazuya , Yuki Kazuaki , Nakazawa Yosuke , Onda Shouji 
Published: July 2015

SUMMARYThis paper proposes a restart control method for position sensorless PMSM drive systems without a potential transformer for railway vehicle traction. This method can estimate the initial rotor speed and position under coasting conditions over the entire speed range. The method can also be used when the back‐EMF voltage is higher than the inverter DC link voltage. The proposed method is verified by experiments using a 200‐kW PMSM.
Formation of Electrical Machinery Technology in the Edo Period of Japan
Authors: Inui Akifumi , Yamamoto Mitsuyoshi , Kawaguchi Yoshihiro 
Published: July 2015

SUMMARYIn the early Meiji era western civilization flowed into Japan, and the concept of “civilization and enlightenment” was established. In the field of electricity, the electric telegraph and electric lighting spread nationwide. This can be credited to the scientific and technological development nurtured during the Edo Period (1603–1868). In 1720, in order to improve the encouragement of new industry and medical technology, Shogun Yoshimune Tokugawa removed the embargo on the importation of books unrelated to Christianity from the Netherlands. As a result, European natural science made its way into Japan, opening the way for the formation of electrical machinery technology. This paper describes electrical machinery technology in Japan in comparison with that of Western Europe at the time of the Edo period. Many people contributed to the formation of electrical engineering in the Edo period, but three persons, Gennai Hiraga, Soukichi Hashimoto, Koumin Kawamoto, are considered to have made especial contributions to the formation of electrical engineering due to their broad knowledge and efforts.
Regioselective Synthesis of 6‐Vinyl‐3,6‐dihydropyridine‐2(1H)‐ones through Simple Addition of a Vinylmagnesium “Ate” Complex to 2‐Pyridones
Authors: Sośnicki Jacek G. , Dzitkowski Przemysław , Struk Łukasz 
Published: July 2015

AbstractA highly nucleophilic vinylation reagent, lithium vinyldimethylmagnesate (vinylMe2MgLi), is obtained by mixing vinylmagnesium chloride (1 equiv.) and MeLi (in diethoxymethane; 2 equiv.). The application of this new reagent in the completely regioselective synthesis of 6‐vinyl‐3,6‐dihydro‐1H‐pyridin‐2(1H)‐ones by simple 1,6‐additions to 2‐pyridones is described. Examination of the scope and limitations of the addition revealed the influence on the efficiency of the 6‐vinylation reaction of substituents on the nitrogen atom and on the 2‐pyridone ring.