bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sociologie pragmatique : mode d'emploi
Authors: Barthe Yannick , de Blic Damien , Heurtin Jean-Philippe , Lagneau Éric , Lemieux Cyril , Linhardt Dominique , Moreau de Bellaing Cédric , Rémy Catherine , Trom Danny 
Published: January 2014

En trente ans, la « sociologie pragmatique » (aussi dénommée « sociologie des épreuves ») a produit des enquêtes empiriques touchant à l’ensemble des domaines de la vie sociale. En conformité avec les postulats théoriques qu’ils entendaient défendre, les chercheurs qui se reconnaissent dans ce courant sociologique ont mis au point des façons sensiblement nouvelles de conduire l’enquête, de collecter les données, d’explorer les terrains, de penser par cas et de se servir des controverses et des affaires comme points d’entrée dans l’ordre social et dans la question de sa problématique reproduction. L’objectif de cet article est de caractériser en dix points le style pragmatique en sociologie et de préciser ce que sont ses réquisits méthodologiques et ses conséquences pratiques dans la conduite du travail d’enquête.
Les négociants dans les assemblées de la Nation française à Cadix : représentation, assiduité et implication du négoce dans les affaires du Consulat de France (1716-1728)
Authors: Gouic Olivier Le 
Published: January 2014

Au début du xviiie siècle, Cadix s’impose à toute l’Europe comme le port unique du commerce avec l’Amérique espagnole, détenteur du monopole de la Carrera de Indias. Issues de toute l’Europe, des colonies de marchands s’installent dans la ville pour fournir au commerce d’Amérique toutes les productions des manufactures du vieux continent et en retirer les piastres et « matières d’argent » que rapportent les Flottes et les Galions. La colonie marchande française, qui compte 60 à 70 maisons, est alors, de loin, la plus puissante. Lorsqu’en 1716 le nouveau consul Pierre Nicolas Partyet s’installe dans la ville, il entend reprendre en main la nation française et renforcer le contrôle de la monarchie sur une communauté de négociants aussi ardents à défendre leurs privilèges qu’à contourner les règlements pour s’immiscer dans le commerce des Indes espagnoles. Pendant le consulat de Partyet, les assemblées de la nation, contrôlées par les plus puissants marchands de la colonie, sont le théâtre des vives tensions qui existent entre le représentant du roi et les députés élus par les négociants. Pour rétablir la discipline, Louis XV promulgue en mai 1728 une ordonnance qui règlemente le fonctionnement du consulat et définit pour le siècle à venir les droits et les devoirs des Français installés à Cadix.
Résonance d’une « perversion » : tanner la peau humaine en Vendée militaire (1793-1794)
Authors: Rolland-Boulestreau Anne 
Published: January 2014

En 1903, un article publié dans une revue angevine, spécialisée dans l’édition des sources révolutionnaires, cite des archives d’octobre 1794, impliquant des notables d’une petite ville proche d’Angers, les Ponts-de-Cé. Ils y dénoncent un chirurgien du quatrième bataillon des Ardennes qui se serait livré à une expérience inouïe : tanner des peaux humaines, prélevées sur une trentaine de cadavres vendéens, fusillés après la Virée de galerne, en décembre 1793. Ces notables ont-ils affabulé et travesti la vérité neuf mois après les faits, pour mieux faire oublier leur propre rôle durant la guerre de Vendée ? L’auteur de l’article de 1903 ne veut-il pas incriminer le rôle de la République en Vendée ? Les historiens de la Contre-Révolution sont partagés devant ce fait macabre. Il s’agira, à partir des archives départementales de Maine-et-Loire et du Service Historique de la Défense, de montrer l’intérêt historiographique d’une telle affaire.
La pêche à Terre-Neuve et le commerce international : deux activités complémentaires au XVIe siècle
Authors: Casado Alonso Hilario 
Published: January 2014

L’article étudie la pêche à Terre-Neuve dans la
seconde moitié du xvie siècle à partir de
415 polices d’assurance enregistrées devant le Consulat de Burgos, un
des principaux centres d’assurance en Europe à cette époque. Ces
documents détaillent d’une part les caractéristiques desdits voyages :
prix, dangers encourus, participants, destination, routes, provenance
des bateaux et des marins, etc. Ils sont à replacer parmi les 10 397
polices d’assurance conservées qui permettent de reconstituer au total
4743 expéditions entre 1565 et 1619. On constate que les maîtres, les
propriétaires et les équipages des navires combinaient la pêche à
Terre-Neuve avec le commerce international qui formaient deux
activités complémentaires, sans qu’il y ait spécialisation entre les
différentes activités. Les flottes espagnoles, portugaises et
françaises développaient un pluriactivité, moyen de diversifier les
affaires et par voie de conséquence de répartir les risques.
La mutualisation des risques et ses effets sur le fonctionnement des gouvernements des villes côtières portugaises au Moyen Âge
Authors: Farelo Mário 
Published: January 2014

Selon les sources historiques disponibles, la protection des risques assumés par les marins portugais au Moyen Âge a pris moins la forme de l’assurance que de la pré-assurance. Cette dernière s’est organisée notamment autour de deux institutions, à savoir les caisses communes des marchands (bolsas dos mercadores) et les diverses associations urbaines à but caritatif connues sous les désignations de confréries et d’hôpitaux de marchands et de pêcheurs. Distinctes dans leurs organisations, leurs objectifs et leurs relations, l’une et l’autre ont constitué des rouages dans la visibilité des oligarchies urbaines et de leurs relations avec les autres pouvoirs établis dans la ville.
Interactions between Restorative Dentistry and Periodontics: Surgical Procedure (Part I)
Authors: Tonetto Mateus Rodrigues , Pinto Shelon Cristina Souza , Borges Alvaro Henrique , Saad José Roberto Cury , Bandeca Matheus Coelho , Porto Thiago Soares , Barud Hélida Gomes de Oliveira 
Published: January 2014

ABSTRACTThe best way to enhance gingival health and minimize trauma is to avoid contact of the gingivae with restorative materials. Subgingival finish lines are not periodontally advantageous. Crown lengthening is a periodontal resective procedure, aimed at removing periodontal tissue support to increase the clinical crown height. Periodontal health is of paramount importance to understand the concept of biologic width, indications, techniques and other principles as well as some possible limitations. This article aims to discuss these concepts and its relationship to periodontal health and restorative dentistry. The importance of restorative margin location and contours related to periodontal health are also addressed in order that the restorative dentist can use crown lengthening as part of an overall treatment plan in a controlled and predictable manner, taking into account biological factors.How to cite this articleSouza Pinto SC, Tonetto MR, de Oliveira Barud HG, Porto TS, Saad JRC, Borges AH, Bandeca MC. Interactions between Restorative Dentistry and Periodontics: Surgical Procedure (Part I). World J Dent 2013;4(4):276-281.
Urinary retention
Authors: Hernandez David Hernández , Tesouro Ricardo Bernardez , Castro-Diaz David 
Published: January 2014

Urinary retention, defined as the inability to void, is a common medical problem. If unidentified and/or untreated, it may become a serious condition that can lead to kidney damage or urosepsis, compromising the patient's life. Acute urinary retention (AUR) is usually easy to identify and to treat as patients usually complain of hypogastric pain and anuria. Proper bladder drainage with urethral or suprapubic catheter is the first line of treatment, with posterior studies to determine the cause of retention. Chronic urinary retention (CUR) is often much more difficult to identify. It is invariably linked to increased post-void residual urine (PVR), but its asymptomatic nature makes it often a hidden condition. There is a wide range of intrinsic and extrinsic, obstructive and non-obstructive causes affecting the lower urinary tract, which can lead to urinary retention. Due to the differences in urinary physiology and in order to simplify diagnosis and management, these are usually studied separately in men and in women. Management consists of a variety of options depending on the cause of retention, including conservative treatment, drug therapy and several forms of surgery. In this review, we make an overview of the main causes of acute and chronic urinary retention in men and women, focusing on the main aspects of diagnosis and management.
Medicare Advantage Plan Star Ratings and County Social Vulnerability
Authors: Gupta Avni , Silver Diana , Meyers David J. , Glied Sherry , Pagán José A. 
Published: July 2024

ImportanceThe star rating of a Medicare Advantage (MA) plan is meant to represent plan performance, and it determines the size of quality bonuses. Consumer access to MA plans with a high star rating may vary by the extent of social vulnerability in geographic regions.ObjectiveTo examine the association between a county’s Social Vulnerability Index (SVI) and the star rating of a county’s MA plans.Design, Setting, and ParticipantsThis cross-sectional study used 2023 Centers for Medicare &amp;amp; Medicaid Services data for all MA plans linked to 2020 county-level SVI data from the Centers for Disease Control and Prevention. Data were analyzed from March to October 2023.ExposureQuintile rank of county based on composite and theme-specific SVI scores, with quartile 1 (Q1) representing the least vulnerable counties and Q5, the most vulnerable counties. The SVI is a multidimensional measure of a county’s social vulnerability across 4 themes: socioeconomic status, household characteristics (such as disability, age, and language), racial and ethnic minority status, and housing type and transportation.Main Outcomes and MeasuresCounty-level mean star rating and the number of MA plans with low-rated (&amp;lt;3.5 stars), high-rated (3.5 or 4.0 stars), and highest-rated (≥4.5 stars) plans.ResultsAcross 3075 counties, the median county-level star rating was 4.1 (IQR, 3.9-4.3) in Q1 counties and 3.8 (IQR, 3.6-4.0) in Q5 counties (P &amp;lt; .001). The mean star rating of MA plans was lower (difference, −0.24 points; 95% CI, −0.28 to −0.21 points; P &amp;lt; .001), the number of low-rated plans was higher (incidence rate ratio, 1.81; 95% CI, 1.61-2.06; P &amp;lt; .001), and the number of highest-rated plans was lower (incidence rate ratio, 0.75; 95% CI, 0.70-0.81; P &amp;lt; .001) in Q5 counties compared with Q1 counties. Similar patterns were found across theme-specific SVI score quintiles and for 2022 star ratings.Conclusions and RelevanceIn this cross-sectional study, the most socially vulnerable counties were found to have the fewest highest-rated plans for MA beneficiaries. As MA enrollment grows in socially vulnerable regions, this may exacerbate regional differences in health outcomes for Medicare beneficiaries.
Investigation of Microstructure, Mechanical, and Tribological Behavior of Nano‐Y2O3, TiO2, ZrO2‐Dispersed W–Ni–Nb–Mo–Zr Alloys Fabricated by Spark Plasma Sintering
Authors: Khan Atiqur Rahman , Patra Anshuman , Chaira Debasis , Sahoo Santosh Kumar , Babu Diraviam Arvindha 
Published: July 2024

W–Ni–Nb–Mo–Zr alloys with 1.0 weight% (wt%) Y2O3 (alloy A), TiO2 (alloy B), ZrO2 (alloy C) dispersion synthesized by mechanical alloying for 20 h have been subjected to spark plasma sintering at 1150 °C with 65 MPa pressure and 5 min holding time. X‐ray diffraction analysis reveals the occurrence of intermetallics (W2Zr, NiNb, Ni10Zr7, MoNi), which improves the strength of the alloys. Field‐emission scanning electron microscopy analysis shows that the grain size of alloy A is less compared to alloy B and C. Energy‐dispersive spectroscopy reveals the presence of oxides at the matrix interface. Maximum % relative sintered density, ultrahigh hardness, excellent compressive strength, % compressive strain at the maximum compressive load of 99.5%, 20.42 GPa of 2.55 GPa, 9.7%, respectively, have been recorded for alloy A. Maximum texture intensity of 1.5 is recorded for alloy A which supports the superior mechanical properties. The specific wear rate of alloy A is around 2.78 times less compared to alloy C. The crystal structure transformation of ZrO2 from monoclinic to tetragonal after sintering deteriorates the mechanical properties and wear resistance in alloy C. The article also reports the operative wear mechanism in the studied oxide dispersion‐strengthened alloy.
Pathogenesis‐Guided Engineering: pH‐Responsive Imprinted Polymer Co‐Delivering Folate for Inflammation‐Resolving as Immunotherapy in Implant‐Related Infections
Authors: Costa Raphael C. , Nagay Bruna E. , Villa Javier E. L. , Sotomayor Maria D. P. T. , Neres Lariel Chagas da Silva , Benso Bruna , Aguayo Sebastian , Sacramento Catarina M. , Ruiz Karina G. S. , Spada Fernanda P. , de Avila Erica Dorigatti , da Costa Monique G. , Faverani Leonardo P. , Cintra Luciano T. A. , Souza Joāo Gabriel S. , Barão Valentim A. R. 
Published: July 2024

AbstractFolate (FT) is a suitable targeting ligand for folate receptors (FOLR) overexpressed on inflamed cells. Thus, FT‐loaded polymers can be used as FOLRs‐targeted immunotherapy to positively modulate the inflammatory process. A novel biodegradable imprinted polymer with a FT delivery mechanism driven by pH changes [PCL‐MIP@FT] is designed with molecularly imprinted technology. The pH mechanism is validated in vitro, demonstrating that an acidic environment accelerated and increased the release of FT for a period of 7 days (∼100 µg mL−1). For the first time, FT receptors (FOLR‐1 and FOLR‐3) are discovered and also overexpressed on activated human gingival fibroblasts, representing a favorable target in the oral environment. Although FT itself does not have antimicrobial effects, the nanomechanical properties of biofilm are changed after topical FT administration. In vivo systemic toxicity of PCL‐MIP@FT has been demonstrated to be a safe biomaterial (up to 1.3 mg kg−1). When the PCL‐MIP@FT is assessed in the subcutaneous tissue, it promoted an alleviating inflammation and may be able to stimulate tissue repair. The present findings have demonstrated the reliable in vitro and in vivo anti‐inflammatory actions of FT‐loaded polymer and support its use as a novel drug‐free therapeutic platform for modulating and mitigating inflammatory responses in dental implant‐related infections.
3D Nano‐Printed Bistable Microlens Actuator for Reconfigurable Micro‐Optical Systems
Authors: Calikoglu Aybuke , Lux Florian , Taege Yanis , Zappe Hans , Ataman Çağlar 
Published: July 2024

AbstractThe integration of multiple functional microscopy methods into a single, miniaturized instrument, known as multimodal endomicroscopy, presents significant challenges due to the often conflicting optical requirements of each imaging modality. In this study, the use of 3D nano‐printing based on two‐photon polymerization for the monolithic manufacturing of complete optical MEMS devices is investigated as an enabling platform for multimodal endoscopy. This approach offers unparalleled miniaturization, design flexibility, and alignment precision of micro‐optics and actuators. In particular, the design, fabrication, and characterization of a monolithically 3D nano‐printed bistable microlens actuator are discussed. Bistability allows the microlens to switch between two stable positions, thereby changing the focus distance and numerical aperture. The actuator features two coils with opposing current directions, which create a magnetic field gradient around a polymer micro‐magnet. This configuration allows for robust switching between stable positions with an average axial distance of 168.3 ± 7.3 µm. Experiments conducted to ascertain the optical characterization of the actuator demonstrate its capacity to transition between different optical modes. The beam widths are measured to be in the range of 4.1 ± 0.2 µm in the high‐resolution mode and 11.3 ± 1.1 µm in the extended depth of focus mode.
Self‐Nanoformulating Poly(2‐oxazoline) and Poly(2‐oxazine) Copolymers Based Amorphous Solid Dispersions as Microneedle Patch: A Formulation Study
Authors: D'Amico Carmine , Ziegler Anna‐Lena , Kemell Marianna , Molinaro Giuseppina , Luxenhofer Robert , Santos Hélder A. 
Published: July 2024

AbstractA pioneering approach in the domain of transdermal drug delivery systems (TDDS) is introduced by using microneedles (MNs) fabricated from an amorphous solid dispersion comprising only a model drug and an amphiphilic block copolymer to form a drug nanoformulation upon MN dissolution. To maximize drug loading and ensure consistent release, a minimalist formulation that achieves 40 wt% drug loading, which is a significant improvement over existing methods, is developed. Using scanning electron microscopy, the morphology of MNs is examined across a spectrum of drug loading ratios, demonstrating the consistency in structure and integrity. Mechanical testing confirms the MNs' proficiency in effective skin penetration. A comparative study on the formation of polymeric micelles underscores the innovative concept of a “nano‐in‐micro drug delivery system”. The results demonstrate that MNs manufactured from an amorphous solid dispersion of drug and amphiphilic block copolymer with ultra‐high loading enhance the availability and release dynamics of hydrophobic drugs, positioning them as a tool for enhancing TDDS. This study sets a new benchmark in the utilization of polymer‐drug nanoformulations for transdermal applications and underscores the capacity for high drug loading and the creation of adaptable drug delivery mechanisms for the studied amphiphilic block copolymer.
Oxidative Photochemical Cyclisations to Access Spiroketals
Authors: Trevorrow Jonathan , Sibanda Nhlanhla , O'Kearney‐McMullan Anne , Miller Potucka Lucie , Dobbs Adrian P. 
Published: July 2024

AbstractThe spiroketal moiety is an important substructure within many biological natural products. One method to access them is via the oxidative cyclisation of a pendant hydroxyl group on to a pre‐formed pyran. However applications of this methodology have been severely limited by requiring the use of toxic oxidants, such as lead (IV) tetraacetate or mercuric oxide. Herein we report a high yielding photochemical route to prepare complex spiroketals using an oxidative photochemical approach employing iodine monochloride and sodium acetate and demonstrate the methodology to the synthesis of a number of insect pheromones.
Benzene‐1,3‐disulfonyl fluoride and Benzene‐1,3,5‐trisulfonyl fluoride: Low‐Cost, Stable, and Selective Reagents for SuFEx‐Driven Deoxyazidation
Authors: Vishwakarma Dharmendra S. , Moses John E. 
Published: July 2024

AbstractThe development of synthetic methods for the synthesis of organic azides is highly important, given their critical role in advancing click chemistry over the last twenty years. We report a reagent‐economical, reliable, and scalable synthesis of alkyl azides from primary and secondary alcohols. This robust click method capitalizes on the synergistic interaction between Sulfur Fluoride Exchange (SuFEx) reagents – specifically, benzene‐1,3‐disulfonyl fluoride (BDSF) or benzene‐1,3,5‐trisulfonyl fluoride (BTSF) – and trimethylsilyl azide (TMSN3). The method offers procedural ease, accommodates a wide array of substrates, and enables late‐stage functionalization. Additionally, we demonstrate the protocol‘s adaptability by validating a straightforward one‐pot deoxyazidation‐CuAAC sequence for drug discovery applications.
Biomimetic Supramolecular Assembly with IGF‐1C Delivery Ameliorates Inflammatory Bowel Disease (IBD) by Restoring Intestinal Barrier Integrity
Authors: Fu Enze , Qian Meng , He Ningning , Yin Yilun , Liu Yue , Han Zhibo , Han ZhongChao , Zhao Qiang , Cao Xiaocang , Li Zongjin 
Published: July 2024

AbstractThe management of dysfunctional intestinal epithelium by promoting mucosal healing and modulating the gut microbiota represents a novel therapeutic strategy for inflammatory bowel disease (IBD). As a convenient and well‐tolerated method of drug delivery, intrarectal administration may represent a viable alternative to oral administration for the treatment of IBD. Here, a biomimetic supramolecular assembly of hyaluronic acid (HA) and β‐cyclodextrin (HA‐β‐CD) for the delivery of the C domain peptide of insulin‐like growth factor‐1 (IGF‐1C), which gradually releases IGF‐1C, is developed. It is identified that the supramolecular assembly of HA‐β‐CD enhances the stability and prolongs the release of IGF‐1C. Furthermore, this biomimetic supramolecular assembly potently inhibits the inflammatory response, thereby restoring intestinal barrier integrity. Following HA‐β‐CD‐IGF‐1C administration, 16S rDNA sequencing reveals a significant increase in the abundance of the probiotic Akkermansia, suggesting enhanced intestinal microbiome homeostasis. In conclusion, the findings demonstrate the promise of the HA‐based mimicking peptide delivery platform as a therapeutic approach for IBD. This biomimetic supramolecular assembly effectively ameliorates intestinal barrier function and intestinal microbiome homeostasis, suggesting its potential for treating IBD.
High‐Performance Sensing Platform Based on Morphology/Lattice Collaborative Control of Femtosecond‐Laser‐Induced MXene‐Composited Graphene
Authors: Su Ruige , Liang Misheng , Yuan Yongjiu , Huang Chaojun , Xing Wenqiang , Bian Xiaomeng , Lian Yiling , Wang Bo , You Zheng , You Rui 
Published: July 2024

AbstractFlexible sensors based on laser‐induced graphene (LIG) are widely used in wearable personal devices, with the morphology and lattice arrangement of LIG the key factors affecting their performance in various applications. In this study, femtosecond‐laser‐induced MXene‐composited graphene (LIMG) is used to improve the electrical conductivity of graphene by incorporating MXene, a 2D material with a high concentration of free electrons, into the LIG structure. By combining pump‐probe detection, laser‐induced breakdown spectroscopy (LIBS), and density functional theory (DFT) calculations, the morphogenesis and lattice structuring principles of LIMG is explored, with the results indicating that MXene materials are successfully embedded in the graphene lattice, altering both their morphology and electrical properties. The structural sparsity and electrical conductivity of LIMG composites (up to 3187 S m−1) are significantly enhanced compared to those of LIG. Based on these findings, LIMG has been used in wearable electronics. LIMG electrodes are used to detect uric acid, with a minimum detection limit of 2.48 µM. Additionally, LIMG‐based pressure and bending sensors have been successfully used to monitor human limb movement and pulse. The direct in situ femtosecond laser patterning synthesis of LIMG has significant implications for developing flexible wearable electronic sensors.