bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development of a Complex Orientation Program for Multidisciplinary Training
Authors: Hemingway Maureen , Morrissey Lisa 
Published: May 2013

AbstractProviding complex orientation and multidisciplinary training for perioperative personnel of a newly constructed health care facility with new surgical suites proved both challenging and valuable to nurse leaders. Despite the need for such training, a program to teach groups across all disciplines regarding technological advances specific to the OR and to orient them to a new facility did not exist previously. To address this, we developed a multiphase educational initiative that involved orientation, technology training, and multidisciplinary simulation. The project required extensive planning, high‐level collaboration, and use of the hospital's information technology systems, all while staff members continued to provide care for patients undergoing surgically complex procedures. The successful implementation of this program ensured that staff members were proficient in new OR technology and oriented to the new facility before occupancy began.
Top 10 Patient Safety Issues: What More Can We Do?
Authors: Steelman Victoria M. , Graling Paula R. 
Published: May 2013

AbstractA 2012 survey of AORN members identified the top 10 safety issues reported by perioperative nurses. These nurses are in a unique position to understand the errors and the unreported near misses that occur in the OR. For each of the top‐rated safety issues that RNs identified, we discuss the evidence of risk and contributing factors and make targeted recommendations for further improvement in perioperative safety with the goal of mitigating risk and improving patient outcomes.
A Brief Review on the Human Encyclopedia of DNA Elements (ENCODE) Project
Authors: Qu Hongzhu , Fang Xiangdong 
Published: May 2013

Abstract
The ENCyclopedia Of DNA Elements (ENCODE) project is an international research consortium that aims to identify all functional elements in the human genome sequence. The second phase of the project comprised 1640 datasets from 147 different cell types, yielding a set of 30 publications across several journals. These data revealed that 80.4% of the human genome displays some functionality in at least one cell type. Many of these regulatory elements are physically associated with one another and further form a network or three-dimensional conformation to affect gene expression. These elements are also related to sequence variants associated with diseases or traits. All these findings provide us new insights into the organization and regulation of genes and genome, and serve as an expansive resource for understanding human health and disease.
Mediator Complex Dependent Regulation of Cardiac Development and Disease
Authors: Grueter Chad E. 
Published: May 2013

Abstract
Cardiovascular disease (CVD) is a leading cause of morbidity and mortality. The risk factors for CVD include environmental and genetic components. Human mutations in genes involved in most aspects of cardiovascular function have been identified, many of which are involved in transcriptional regulation. The Mediator complex serves as a pivotal transcriptional regulator that functions to integrate diverse cellular signals by multiple mechanisms including recruiting RNA polymerase II, chromatin modifying proteins and non-coding RNAs to promoters in a context dependent manner. This review discusses components of the Mediator complex and the contribution of the Mediator complex to normal and pathological cardiac development and function. Enhanced understanding of the role of this core transcriptional regulatory complex in the heart will help us gain further insights into CVD.
Intraoperative intracranial pressure and cerebral perfusion pressure for predicting surgical outcome in severe traumatic brain injury
Authors: Tsai Tai‐Hsin , Huang Tzuu‐Yuan , Kung Sui‐Sum , Su Yu‐Feng , Hwang Shiuh‐Lin , Lieu Ann‐Shung 
Published: May 2013

AbstractIntraoperative intracranial pressure (ICP) and cerebral perfusion pressure (CPP) were evaluated for use as prognostic indicators after surgery for severe traumatic brain injury (TBI), and threshold ICP and CPP values were determined to provide guidelines for patient management. This retrospective study reviewed data for 66 patients (20 females and 46 males) aged 13–83 years (average age, 48 years) who had received decompressive craniectomy and hematoma evacuation for severe TBI. The analysis of clinical characteristics included Glascow Coma Scale score, trauma mechanism, trauma severity, cerebral hemorrhage type, hematoma thickness observed on computed tomography scan, Glasgow Outcome Scale score, and mortality. Patients whose treatment included ICP monitoring had significantly better prognosis (p < 0.001) and significantly lower mortality (p = 0.016) compared to those who did not receive ICP monitoring. At all three major steps of the procedure, i.e., creation of the burr hole, evacuation of the hematoma, and closing of the wound, intraoperative ICP and CPP values significantly differed. The ICP and CPP values were also significantly associated with surgical outcome in the severe TBI patients. Between hematoma evacuation and wound closure, ICP and CPP values differed by 6.8 ± 4.5 and 6.5 ± 4.6 mmHg, respectively (mean difference, 6 mmHg). Intraoperative thresholds were 14 mmHg for ICP and 56mmH for CPP. Monitoring ICP and CPP during surgery improves management of severe TBI patients and provides an early prognostic indicator. During surgery for severe TBI, early detection of increased ICP is also crucial for enabling sufficiently early treatment to improve surgical outcome. However, further study is needed to determine the optimal intraoperative ICP and CPP thresholds before their use as subjective guidelines for managing severe TBI patients.
Disorganized attachment and reproductive strategies
Authors: Lewis Andrew J. , Tooley Gregory 
Published: May 2013

AbstractDel Giudice provides an extension of the life history theory of attachment that incorporates emerging data suggestive of sex differences in avoidant male and preoccupied female attachment patterns emerging in middle childhood. This commentary considers the place of disorganized attachment within this theory and why male children may be more prone to disorganized attachment by drawing on Trivers's parental investment theory.
Campylobacteriosis outbreak associated with consumption of undercooked chicken liver pâté in the East of England, September 2011: identification of a dose–response risk
Authors: EDWARDS D. S. , MILNE L. M. , MORROW K. , SHERIDAN P. , VERLANDER N. Q. , MULLA R. , RICHARDSON J. F. , PENDER A. , LILLEY M. , REACHER M. 
Published: May 2013

SUMMARYA foodborne outbreak with 49 cases (22 culture positive forCampylobactersp.) following a wedding party in the East of England was investigated. A retrospective cohort study identified an association between consumption of chicken liver pâté and infection withCampylobacter jejuni/coli. There was a statistically significant association between dose (amount of chicken liver pâté eaten) and the risk of disease [‘tasted’: odds ratio (OR) 1·5, 95% confidence interval (CI) 0·04–∞; ‘partly eaten’: OR 8·4, 95% CI 1·4–87·5; ‘most or all eaten’: OR 36·1, 95% CI 3·3–2119). The local authority found evidence that the preparation of chicken livers breached Food Standards Agency's guidelines. This epidemiological investigation established a clear dose–response relationship between consumption of chicken liver pâté and the risk of infection withCampylobacter. The continuing need to raise public awareness of the risk to human health posed by undercooked chicken liver is evident.
Eating for the better: a social marketing review (2000–2012)
Authors: Carins Julia E , Rundle-Thiele Sharyn R 
Published: May 2013

AbstractObjectiveThe present study sought to identify both the ingredients for success and the potential impediments to social marketing effectiveness for healthy eating behaviour, focusing on studies conducted over the last 10 years.DesignA comprehensive literature review was undertaken examining seventeen databases to identify studies reporting the use of social marketing to address healthy eating. Thirty-four empirical studies were analysed to examine the effectiveness of social marketing interventions to improve healthy eating behaviour using Andreasen's (2002) social marketing benchmark criteria. Statistical analysis was undertaken to quantitatively evaluate whether effectiveness varied between study categories (subsets).SettingHealthy eating empirical studies published from 2000 onwards.SubjectsEmpirical studies that self-identified as social marketing.ResultsSixteen social marketing studies (subset 1) were identified in the review. These were systematic studies which sought to change behaviour through tailored solutions (e.g. use of marketing tools beyond communication was clearly evident) that delivered value to the target audience. For these sixteen studies, the mean number of criteria identified was five. Six studies met all six criteria. Positive change to healthy eating behaviour was found in fourteen of sixteen studies. The sixteen studies that met the definition of social marketing used significantly more of Andreasen's (2002) criteria and were more effective in achieving behavioural change than the eighteen studies in subset 2.ConclusionsSocial marketing is an involved process and it is important that studies identifying as social marketing adopt social marketing benchmark criteria. Social marketing when employed to its full extent offers the potential to change healthy eating.
Efficacy and safety of external beam radiation therapy in non-functioning pituitary adenomas: a case–control, nested in a cohort study
Authors: Vargas Guadalupe , González Baldomero , Mendoza Victoria , Guinto Gerardo , López-Félix Blas , Mercado Moisés 
Published: May 2013

AbstractBackground and objectivesRecurrence is frequent in surgically treated non-functioning pituitary adenomas (NFPA). The use of radiation therapy (RT) to prevent recurrence has to be weighted against the potential side effects, particularly, hypopituitarism. Our objective was to evaluate the efficacy and safety of RT in postoperative patients with NFPA with adenoma remnant.Patients and methodsThe 3- and 5-year outcome of 51 patients with NFPA with a remnant after surgery that received RT (cases) was compared with that of 61 subjects who did not receive RT (controls). Cases and controls were matched for postoperative remnant size, cavernous sinus invasion, age and gender.ResultsTumour volume decreased in the radiated group from a median of 1,601 mm3 to 816 mm3 after 5 years of follow-up (p = 0·01, 50% tumour volume reduction). In the non-radiated controls median tumour volume decreased at 3 years but increased again after 5 years (baseline 1,415 mm3, 5 years 1,204 mm3, p = 0·93). Recurrence rate was 4% for the radiated group and 29% for the controls (OR 0·10, 95% CI 0·01–0·04, p = 0·02). Although pituitary hormone deficiencies at baseline were more prevalent in the radiated group, after 5 years, both groups showed a significant worsening of pituitary function. No RT-related side effects were recorded.ConclusionPostoperative RT is effective in preventing tumour regrowth in NFPA patients with postoperative remnants. The fact that hypopituitarism is highly prevalent even in non-radiated patients should allow a more generalised use of this treatment modality.
Trust and arena size: expectations, institutions, and general trust, and critical population and group sizes
Authors: ELSNER WOLFRAM , SCHWARDT HENNING 
Published: May 2013

AbstractWhile trust and group size in socio-economic processes have been well investigated separately, approaches to synergize them have been rare. After addressing basic conditions for institutionalized cooperation, the agency capability of preferential mixing is introduced in order to determine the carrier group of an institution of cooperation. That platform typically assumes a meso-size smaller than the initial arena. Habituation and generalization within and across overlapping platforms then may lead to first contextual trust. This has to be carried over from individual platforms into the larger public of the whole economy to constitute general trust. The practical relevance of this analysis is illustrated through the fact that even superficially similar economies show different socio-economic performance and trajectories. Our results suggest investigating their inner deep structure of overlapping meso-sized platforms as a critical factor.
Fish Passage through Culverts in Central Michigan Warmwater Streams
Authors: Briggs Andrew S. , Galarowicz Tracy L. 
Published: May 2013

Abstract
Road culverts can alter stream flow, remove fish habitat, and limit fish movement. Little is known about the effects of culverts on fish movement in low-order, low-gradient streams in an agricultural setting. Eleven sites on first- and second-order streams in central Michigan were examined for the effects of culvert type (box, bottomless box, pipe arch, and bottomless pipe arch) on fish passage in an agricultural setting. The selected culverts were not obvious barriers to fish passage as none were perched above the stream. Four reaches (two upstream and two downstream of a culvert) were sampled three times in spring, summer, and fall 2011 at each site. Mark–recapture sampling was used to observe fish movement, and the probability of fewer fish being found upstream of a culvert relative to downstream was modeled with logistic regression. Based on recapture movements, limited passage was assumed for at least one fish species during each season at a pipe arch culvert and for one species during summer at a box culvert. The best models from logistic regression revealed that culvert length had the largest effect on the proportion of Creek Chub Semotilus atromaculatus being found upstream out of the variables used. FishXing, a computer program used to predict fish passage through culverts, predicted that five culverts had passage-limiting flows to either Western Blacknose Dace Rhinichthys obtusus or Creek Chub during at least one season. However, all culverts were predicted to have some passable flows during each season (except one culvert during one season). Results suggest that even though culverts may not be obvious barriers, fish passage can still be limited.
Received November 15, 2012; accepted March 12, 2013
DeMix: deconvolution for mixed cancer transcriptomes using raw measured data
Authors: Ahn Jaeil , Yuan Ying , Parmigiani Giovanni , Suraokar Milind B. , Diao Lixia , Wistuba Ignacio I. , Wang Wenyi 
Published: May 2013

Abstract
Motivation: Tissue samples of tumor cells mixed with stromal cells cause underdetection of gene expression signatures associated with cancer prognosis or response to treatment. In silico dissection of mixed cell samples is essential for analyzing expression data generated in cancer studies. Currently, a systematic approach is lacking to address three challenges in computational deconvolution: (i) violation of linear addition of expression levels from multiple tissues when log-transformed microarray data are used; (ii) estimation of both tumor proportion and tumor-specific expression, when neither is known a priori; and (iii) estimation of expression profiles for individual patients.
Results: We have developed a statistical method for deconvolving mixed cancer transcriptomes, DeMix, which addresses the aforementioned issues in array-based expression data. We demonstrate the performance of our model in synthetic and real, publicly available, datasets. DeMix can be applied to ongoing biomarker-based clinical studies and to the vast expression datasets previously generated from mixed tumor and stromal cell samples.
Availability: All codes are written in C and integrated into an R function, which is available at http://odin.mdacc.tmc.edu/∼wwang7/DeMix.html.
Contact: wwang7@mdanderson.org
Supplementary information: Supplementary data are available at Bioinformatics online.
Population dynamics of the invasive lithodid crab, Paralithodes camtschaticus, in a typical bay of the Barents Sea
Authors: Dvoretsky Alexander G. , Dvoretsky Vladimir G. 
Published: May 2013

Abstract
Dvoretsky, A. G., and Dvoretsky, V. G. 2013. Population dynamics of the invasive lithodid crab, Paralithodes camtschaticus, in a typical bay of the Barents Sea. – ICES Journal of Marine Science, 70: 1255–1262. We investigated population dynamics of the introduced red king crab, Paralithodes camtschaticus (Tilesius, 1815), in Dalnezelenetskaya Bay, a typical coastal site of the Eastern Murman (Barents Sea) in summer over an 8-year period. In this bay, as in other coastal sites, juvenile crabs were most abundant. Among large crabs, the sex ratio was highly biased to females suggesting the important role of shallow water areas in reproduction of the red king crab. In 2002–2004, the carapace length (CL) frequency distribution of small crabs tended to be bimodal (30 and 60 mm). In 2005–2007 and 2009, crabs with a modal CL of 20 and 40 mm dominated. For small crabs, weight–length relationships were similar in males and females, while for large crabs the relationships differed significantly between sexes. Large males had a greater carapace width (CW) and merus length (ML), and higher CW/CL and ML/CL ratios, than large females due to sexual dimorphism. In 2002–2007, the total number of red king crabs was estimated to be 4100–7400 individuals; in 2008, we observed a marked decline to 350 individuals; in 2009, the total stock increased again to 3760 individuals. The observed patterns are in accordance with the stock dynamics reported for other coastal areas and could be associated with high levels of illegal fishing including recreational diving.
Affordable simultaneous hyperspectral imaging
Authors: Hamid Muhammed Hamed 
Published: May 2013

PurposeThe aim of the research project which resulted in this work is to achieve a cost‐effective approach for instantaneous hyperspectral imaging.Design/methodology/approachThis paper presents a simulation study and an experimental evaluation of a novel imaging spectroscopy technique, where multi‐channel image data are acquired instantaneously and transformed into spectra by using a statistical modelling approach. A digital colour camera equipped with an additional colour filter array was used to acquire an instantaneous single image that was demosaicked to generate a multi‐channel image. A statistical transformation approach was employed to convert this image into a hyperspectral one.FindingsThe feasibility of this method was investigated through extensive simulation and experimental tasks where promising results were obtained.Practical implicationsThe small size of the initially acquired single instantaneous image makes this approach useful for applications where video‐rate hyperspectral imaging is required.Originality/valueFor the first time, a simplified prototype of this novel imaging spectroscopy technique was built and evaluated experimentally. And the results were compared with those of a more ideal simulation study. Recommendations for how to improve the prototype were also suggested as a result of the comparison between the simulation and the prototype evaluation results.
Visual navigation system for small unmanned aerial vehicles
Authors: Ivancsits Christian , Ricky Lee Min‐Fan 
Published: May 2013

PurposeThis paper aims to address three major issues in the development of a vision‐based navigation system for small unmanned aerial vehicles (UAVs) which can be characterized as follows: technical constraints, robust image feature matching and an efficient and precise method for visual navigation.Design/methodology/approachThe authors present and evaluate methods for their solution such as wireless networked control, highly distinctive feature descriptors (HDF) and a visual odometry system.FindingsProposed feature descriptors achieve significant improvements in computation time by detaching the explicit scale invariance of the widely used scale invariant feature transform. The feasibility of wireless networked real‐time control for vision‐based navigation is evaluated in terms of latency and data throughput. The visual odometry system uses a single camera to reconstruct the camera path and the structure of the environment, and achieved and error of 1.65 percent w.r.t total path length on a circular trajectory of 9.43 m.Originality/valueThe originality/value lies in the contribution of the presented work to the solution of visual odometry for small unmanned aerial vehicles.
Examining the stress and coping process of mega‐event employees
Authors: Odio Michael A. , Walker Matthew , Kim May 
Published: May 2013

PurposeThe purpose of this paper is to examine specific stressors present in mega‐event work and the coping strategies used by long‐term mega‐event employees.Design/methodology/approachUsing a general inductive approach to analyze the data and identify themes, semi‐structured interviews with six employees from organizing committees of subsequent National Football League (NFL) Super Bowls, and four employees from the Special Olympics in Greece helped to assess the presence of specific stressors and the corresponding coping strategies.FindingsPatterns relating to the specific stressors (i.e. workload, time pressure, role stressors, job insecurity and work‐family conflict) and several themes emerged across all stressors including the selflessness of the participants in making personal sacrifices due to work demands. A sense of time and place emerged since the participants were cognizant of their role in a prestigious event. Time was also relevant as the end‐date approached which was simultaneously a source of stress and the date when their stress would be over. For most, the period after this end‐date was marked by a sense of sadness and a desire to repeat the experience. Finally, the career paths of the participants appeared to influence their actions and coping strategies.Originality/valueWork in mega‐event organizing committees has not been examined from a stress and coping perspective; this study is the first to examine issues in this unique work setting by applying stress theory. Moreover, the findings suggest that organizing committee employees appraise and cope with stress differently than in more traditional contexts.