bluuebunny/crossref_metadata_2025_split huggingface dataset:
Adjuvant poly(N‐isopropylacrylamide) generates more efficient monoclonal antibodies against truncated recombinant histidine‐rich protein2 of Plasmodium falciparum for malaria diagnosis
Authors: Verma Reena , Ravichandran Ramakrishnan , Jayaprakash Naatamai S. , Kumar Ashok , Vijayalakshmi Mookambeswaran A. , Venkataraman Krishnan 
Published: January 2015

AbstractAdjuvants play an important role in eliciting immune responses and subsequent generation of antibodies with high specificity. Recently, poly(N‐isopropylacrylamide) (PNiPAAm), also known as a “smart” polymer, has been proposed as a potential adjuvant for making antibodies and vaccines. This material exhibits efficient delivery, protection against degradation, and preservation of antigen epitopes. In this work, we used both CFA and smart polymer to develop a highly specific murine monoclonal antibody (mAb) against recombinant truncated histidine rich protein2 (HRP2) of Plasmodium falciparum. Our results indicate that the mAbs developed using these adjuvants were able to recognize recombinant HRP2 and native PfHRP2 protein from spent medium. The mAbs generated against recombinant truncated HRP2 showed better sensitivity to the antigen and importantly mAbs generated using PNiPAAm adjuvant were in the range of 108–109 M–1. The mAbs generated using PNiPAAm are very efficient and sensitive in detecting HRP2. To the best of our knowledge, this is the first report of such comparison having been made between these two adjuvants and we propose that the smart polymer has huge potential as an alternative to CFA. Additionally, we discuss the utility of the mAbs generated through PNiPAAm for specific diagnosis of malaria caused by P. falciparum.
Comprehensive evaluation of two genome‐scale metabolic network models for Scheffersomyces stipitis
Authors: Damiani Andrew L. , He Q. Peter , Jeffries Thomas W. , Wang Jin 
Published: January 2015

ABSTRACTGenome‐scale metabolic network models represent the link between the genotype and phenotype of the organism, which are usually reconstructed based on the genome sequence annotation and relevant biochemical and physiological information. These models provide a holistic view of the organism's metabolism, and constraint‐based metabolic flux analysis methods have been used extensively to study genome‐scale cellular metabolic networks. It is clear that the quality of the metabolic network model determines the outcome of the application. Therefore, it is critically important to determine the accuracy of a genome‐scale model in describing the cellular metabolism of the modeled strain. However, because of the model complexity, which results in a system with very high degree of freedom, a good agreement between measured and computed substrate uptake rates and product secretion rates is not sufficient to guarantee the predictive capability of the model. To address this challenge, in this work we present a novel system identification based framework to extract the qualitative biological knowledge embedded in the quantitative simulation results from the metabolic network models. The extracted knowledge can serve two purposes: model validation during model development phase, which is the focus of this work, and knowledge discovery once the model is validated. This framework bridges the gap between the large amount of numerical results generated from genome‐scale models and the knowledge that can be easily understood by biologists. The effectiveness of the proposed framework is demonstrated by its application to the analysis of two recently published genome‐scale models of Scheffersomyces stipitis. Biotechnol. Bioeng. 2015;112: 1250–1262. © 2015 Wiley Periodicals, Inc.
New, Non‐quinone Fluorogeldanamycin Derivatives Strongly Inhibit Hsp90
Authors: Hermane Jekaterina , Bułyszko Ilona , Eichner Simone , Sasse Florenz , Collisi Wera , Poso Antti , Schax Emilia , Walter Johanna‐Gabriela , Scheper Thomas , Kock Klaus , Herrmann Christian , Aliuos Pooyan , Reuter Günter , Zeilinger Carsten , Kirschning Andreas 
Published: January 2015

AbstractStreptomyces hygroscopicus is a natural producer of geldanamycin. Mutasynthetic supplementation of an AHBA‐blocked mutant with all possible monofluoro 3‐aminobenzoic acids provided new fluorogeldanamycins. These showed strong antiproliferative activity and inhibitory effects on human heat shock protein Hsp90. Binding to Hsp90 in the low nanomolar range was determined from molecular modelling, AFM analysis and by calorimetric studies.
Treating Methanol‐to‐Olefin Quench Water by Minihydrocyclone Clarification and Steam Stripper Purification
Authors: Yang Qiang , Lv Wen‐jie , Shi Lei , Wang Hua‐lin 
Published: January 2015

AbstractIn the chemical industry, methanol‐to‐olefin (MTO) technology is a novel process for producing ethylene and propylene from naphtha thermal cracking. The process of recovering MTO quench water by minihydrocyclone and steam stripping treatment was successfully applied in industrial plants. The fine catalyst in the quench water is removed by the two‐stage minihydrocyclone separation. The method and equipment for this system present various advantages: the quench water can be recycled in the cooling system and prevents heat loss in heat transfer systems; and the stripping tower can be blocked by the catalyst. Maintenance activities are reduced and a stable operation cycle is extended. The proposed treatment process improves the economic efficiency of the MTO device.
Enantioselective Formal [3+3] Cycloadditions of Ketones and Cyclic 1‐Azadienes by Cascade Enamine–Enamine Catalysis
Authors: He Xiao‐Long , Xiao You‐Cai , Du Wei , Chen Ying‐Chun 
Published: January 2015

AbstractAn asymmetric formal [3+3] cycloaddition process with diversely structured aliphatic ketones and electron‐deficient cyclic 1‐azadienes was developed by cascade enamine–enamine catalysis of a cinchona‐based primary amine. This sequence involved a domino Michael addition–Mannich reaction to afford spirocyclic architectures in excellent diastereo‐ and enantioselectivity. Importantly, high regioselectivity was realized for a number of unsymmetrical aliphatic ketone substrates.
Towards Ratiometric Sensing of Amyloid Fibrils In Vitro
Authors: Freire Sonia , Rodríguez‐Prieto Flor , Ríos Rodríguez M. Carmen , Penedo J. Carlos , Al‐Soufi Wajih , Novo Mercedes 
Published: January 2015

AbstractThe aggregation of amyloid‐β peptide and its accumulation in the human brain has an important role in the etiology of Alzheimer’s disease. Thioflavin T has been widely used as a fluorescent marker for these amyloid aggregates. Nevertheless, its complex photophysical behavior, with strong wavelength dependencies of all its fluorescence properties, requires searching for new fluorescent probes. The use of 2‐(2′‐hydroxyphenyl)imidazo[4,5‐b]pyridine (HPIP), which shows two emission bands and a rich excited‐state behavior due to the existence of excited‐state intramolecular processes of proton transfer and charge transfer, is proposed. These properties result in a high sensitivity of HPIP fluorescence to its microenvironment and cause a large differential fluorescence enhancement of the two bands upon binding to aggregates of the amyloid‐β peptide. Based on this behavior, a very sensitive ratiometric method is established for the detection and quantification of amyloid fibrils, which can be combined with the monitoring of fluorescence anisotropy. The binding selectivity of HPIP is discussed on the basis of the apparent binding equilibrium constants of this probe to amyloid‐β (1–42) fibrils and to the nonfibrillar protein bovine serum albumin. Finally, an exhaustive comparison between HPIP and thioflavin T is presented to discuss the sensitivity and specificity of these probes to amyloid aggregates and the significant advantages of the HPIP dye for quantitative determinations.
Unexpected Migratory Insertion Reactions of M(alkyl)2 (M=Zn, Cd) and Diamidocarbenes
Authors: Collins Lee R. , Hierlmeier Gabriele , Mahon Mary F. , Riddlestone Ian M. , Whittlesey Michael K. 
Published: January 2015

AbstractThe electrophilic character of free diamidocarbenes (DACs) allows them to activate inert bonds in small molecules, such as NH3 and P4. Herein, we report that metal coordinated DACs also exhibit electrophilic reactivity, undergoing attack by Zn and Cd dialkyl precursors to afford the migratory insertion products [(6‐MesDAC‐R)MR] (M=Zn, Cd; R=Et, Me; Mes=mesityl). These species were formed via the spectroscopically characterised intermediates [(6‐MesDAC)MR2], exhibiting barriers to migratory insertion which increase in the order MR2 = ZnEt2 < ZnMe2 < CdMe2. Compound [(6‐MesDAC‐Me)CdMe] showed limited stability, undergoing deposition of Cd metal, by an apparent β‐H elimination pathway. These results raise doubts about the suitability of diamidocarbenes as ligands in catalytic reactions involving metal species bearing nucleophilic ligands (M‐R, M‐H).
ChemInform Abstract: Ternary Arsenides Based on Platinum—Indium and Palladium—Indium Fragments of the Cu3Au Type: Crystal Structures and Chemical Bonding.
Authors: Zakharova Elena Yu. , Andreeva Natalia A. , Kazakov Sergey M. , Kuznetsov Alexey N. 
Published: January 2015

AbstractPd5InAs, Pt5InAs, and Pt8In2As are synthesized from stoichiometric mixtures of the elements (silica ampules, 750 °C for 7—10 d and 600 °C for 30—40 d for Pd compounds or 90—120 d for Pt compounds).
ChemInform Abstract: Clay Nanomaterial Thin Film Electrodes for Electrochemical Energy Storage Applications.
Authors: Fatnassi M. , Solterbeck C.‐H. , Es‐Souni M. 
Published: January 2015

AbstractThin films of the smectite clay nanomaterial laponite and trihydroxysilylpropyl‐methylphosphonate nanocomposites thereof are dip coated as suitable low‐cost high performance supercapacitors on Au‐terminated Si substrates.
ChemInform Abstract: Use of Amine Electride Chemistry to Prepare Molybdenum Disulfide Intercalation Compounds.
Authors: Liyanage Amila Udayanga , Lerner Michael M. 
Published: January 2015

AbstractElectride solutions formed by dissolution of Na in en (N2 atmosphere, 60 °C, overnight) are used to generate MoS2 intercalation compounds.
ChemInform Abstract: Synthesis and Characterization of the Ternary Telluroargentate K4[Ag18Te11].
Authors: Davaasuren Bambar , Dashjav Enkhtsetseg , Rothenberger Alexander 
Published: January 2015

AbstractThe title compound is solvothermally synthesized from a mixture of Ag(OAc), K2Te, and elemental Te in en (autoclave, 160 °C, 5 d, 30% yield).
ChemInform Abstract: The Photo‐Nazarov Reaction: Scope and Application.
Authors: Cai Shujun , Xiao Zheming , Shi Yingbo , Gao Shuanhu 
Published: January 2015

AbstractIn contrast to the traditional Broensted‐ or Lewis acid‐promoted Nazarov cyclization reactions the photo‐Nazarov cyclization of vinyl aryl ketones proceeds under mild, neutral or basic conditions.
ChemInform Abstract: Rapid and Efficient Synthesis of Five‐ to Eight‐Membered Cyclic Aminals under Ultrasound Irradiation.
Authors: Ramirez Maria A. , Ortiz Gisela , Levin Gustavo , McCormack Walter , Blanco Maria M. , Perillo Isabel A. , Salerno Alejandra 
Published: January 2015

AbstractThe simple procedure using high intensity ultrasound allows the synthesis of cyclic aminals from diamines (I) with aqueous formaldehyde in excellent yields and very short reaction times.
ChemInform Abstract: Tailoring Atropisomeric Maleimides for Stereospecific [2 + 2] Photocycloaddition—Photochemical and Photophysical Investigations Leading to Visible‐Light Photocatalysis.
Authors: Kumarasamy Elango , Raghunathan Ramya , Jockusch Steffen , Ugrinov Angel , Sivaguru J. 
Published: January 2015

AbstractStereospecific photocycloaddition of atropisomeric maleimides occurs under direct irradiation, triplet‐sensitized UV‐irradiation, and non‐metal catalyzed visible‐light irradiation, leading to exo and endo photoproducts with complete chemoselectivity.
ChemInform Abstract: An Organic Cation as a Silver(I) Analogue for the Arylation of sp2 and sp3 C—H Bonds with Iodoarenes.
Authors: Arroniz Carlos , Denis J. Gabriel , Ironmonger Alan , Rassias Gerasimos , Larrosa Igor 
Published: January 2015

AbstractA new method for the Pd‐catalyzed C—H coupling of a variety of classes of substrates such as benzoic acids, benzamides, 2‐phenylpyridines, benzoquinolines, indoles, thiophenes, polyfluorobenzenes, and 8‐methylquinolines with diverse substituted iodoarenes under silver‐free conditions is developed.
ChemInform Abstract: Synthesis of α‐Chiral‐β,γ‐Unsaturated Carboxylic Acid Derivatives Using Chiral Auxiliaries.
Authors: Poremba Kelsey E. , Lee Victoria A. , Sculimbrene Bianca R. 
Published: January 2015

Abstract(R)‐benzyl‐oxazolidinone and (S,S)‐pseudoephedrine are employed as chiral auxiliaries for the diastereoselective alkylation of vinylacetic acid.
ChemInform Abstract: A New, Efficient, and Catalyst‐Free Microwave‐Assisted Approach for Formation of O‐tert‐Butoxy Carbonates.
Authors: K'tir Hacene , Amira Aicha , Berredjem Malika , Aouf Nour‐Eddine 
Published: January 2015

AbstractAn effective, simple, mild, rapid, solvent‐ and catalyst‐free microwave‐assisted method for the chemoselective O‐tert‐butoxycarbonylation of a wide range of alcohols is presented.
ChemInform Abstract: Synthesis of Cyclic Alkenylsiloxanes by Semihydrogenation: A Stereospecific Route to (Z)‐Alkenyl Polyenes.
Authors: Elbert Bryony L. , Lim Diane S. W. , Gudmundsson Haraldur G. , O'Hanlon Jack A. , Anderson Edward A. 
Published: January 2015

AbstractThe general route to cyclic alkenylsiloxanes, based on the Lindlar hydrogenation of alkynylsilanes, solves a long‐standing selectivity issue in alkynylsilane reduction chemistry.
ChemInform Abstract: Copper Catalyzed Oxidative Cross‐Coupling of Aromatic Amines with 2‐Pyrrolidinone: A Facile Synthesis of N‐Aryl‐γ‐amino‐γ‐lactams.
Authors: Priyadarshini S. , Amal Joseph P. J. , Lakshmi Kantam M. 
Published: January 2015

AbstractThe protocol is limited to aromatic and heteroaromatic amines since alkyl amines, such as benzylamine picolylamine, N‐methylaniline and N,N‐dimethylaniline, do not proceed.
ChemInform Abstract: Metal‐Free Oxidative Direct C(sp3)—H Bond Functionalization of Ethers with α,α‐Diaryl Allylic Alcohols.
Authors: Chu Xue‐Qiang , Meng Hua , Zi You , Xu Xiao‐Ping , Ji Shun‐Jun 
Published: January 2015

AbstractThe new benzoyl tert‐butyl peroxide‐promoted radical alkylation reaction of diaryl allylic alcohols with cyclic and open‐chain ethers results in the formation of α‐aryl‐β‐alkylated carbonyl ketones.
ChemInform Abstract: Enantioselective Conjugate Addition of Aliphatic Thiols to Divergently Activated Electron Poor Alkenes and Dienes.
Authors: Kowalczyk Rafal , Wierzba Aleksandra J. , Boratynski Przemyslaw J. , Bakowicz Julia 
Published: January 2015

AbstractStereoselectivity is secured by the catalyst.
ChemInform Abstract: 4‐(Pentafluorosulfanyl)benzenediazonium Tetrafluoroborate: A Versatile Launch Pad for the Synthesis of Aromatic SF5 Compounds via Cross Coupling, Azo Coupling, Homocoupling, Dediazoniation, and Click Chemistry.
Authors: Okazaki Takao , Laali Kenneth K. , Bunge Scott D. , Adas Sonya K. 
Published: January 2015

AbstractTitle compound (I) undergoes a variety of reactions, including coupling and dediazoniation reactions, to yield various diverse products featuring a 4‐(pentafluorosulfanyl)phenyl moiety.
ChemInform Abstract: A Direct Approach to β‐Keto Sulfones via AgNO3/K2S2O8 Catalyzed Aerobic Oxysulfonylation of Alkenes in Aqueous Medium.
Authors: Singh Atul K. , Chawla Ruchi , Yadav Lal Dhar S. 
Published: January 2015

AbstractThe one‐pot radical route to β‐ketosulfones involves oxysulfonylation of alkenes with air and inexpensive sodium arenesulfinate salts under mild reaction conditions.
ChemInform Abstract: Thiosemicarbazone Salicylaldiminato Palladium(II)‐Catalyzed Alkynylation Couplings Between Arylboronic Acids and Alkynes or Alkynyl Carboxylic Acids.
Authors: Lu Linhua , Chellan Prinessa , Smith Gregory S. , Zhang Xiang , Yan Hong , Mao Jincheng 
Published: January 2015

AbstractTridentate Pd(II) salicylaldiminato‐thiosemicarbazone complexes can efficiently catalyze the alkynylation couplings of a variety of arylboronic acids with alkynes or alkynyl carboxylic acids under mild conditions.
ChemInform Abstract: Facile Synthesis of 3,3′‐Disubstituted 2,2′‐Binaphthyls by Transition‐Metal‐Catalyzed Double Benzannulation.
Authors: Umeda Rui , Tabata Hiromasa , Tobe Yoshito , Nishiyama Yutaka 
Published: January 2015

AbstractThe title compounds (III) are obtained by Cu‐ or Re‐catalyzed double benzannulation of 2‐(phenylethynyl)benzaldehyde with various butadiynes.
ChemInform Abstract: The Synthesis of 1,2‐Diarylindenes via DDQ‐Mediated Dehydrogenative Intramolecular Cyclization.
Authors: Li Yi , Cao Li , Luo Xiaoyan , Deng Wei‐Ping 
Published: January 2015

AbstractAn efficient copper‐promoted dehydrogenative intramolecular cyclization is developed.
ChemInform Abstract: Eaton′s Reagent‐Mediated Domino π‐Cationic Arylations of Aromatic Carboxylic Acids to Iasi‐Red Polymethoxylated Polycyclic Aromatic Hydrocarbons: Products with Unprecedented Biological Activities as Tubulin Polymerization Inhibitors.
Authors: Ghinet Alina , Gautret Philippe , Hijfte Nathalie Van , Lede Bertrand , Henichart Jean‐Pierre , Bicu Elena , Darbost Ulrich , Rigo Benoit , Daich Adam 
Published: January 2015

AbstractThe π‐cationic arylation of methoxy substituted benzoic acids with reactive arenes [e.g. (II)] is developed to provide an optimized synthetic route to phenstatin (V).
ChemInform Abstract: Short and Efficient Route Toward α‐Substituted N‐Arylazetidines from Acetanilides via Mitsunobu Reaction.
Authors: Kern Nicolas , Hoffmann Marie , Weibel Jean‐Marc , Pale Patrick , Blanc Aurelien 
Published: January 2015

AbstractA three step sequence is developed for the synthesis N‐arylazetidines (V) involving aldolization between acetanilines and aldehydes, cyclization by Mitsunobu reaction and azetidinone reduction.
ChemInform Abstract: Interaction of 2‐Naphthol with γ‐Ureidoacetals. A New Method for the Synthesis of 2‐Arylpyrrolidines.
Authors: Gazizov A. S. , Smolobochkin A. V. , Burilov A. R. , Pudovik M. A. 
Published: January 2015

AbstractA convenient single‐stage synthesis of novel 2‐arylpyrrolidines based on the title reaction is developed.
ChemInform Abstract: I2—DMSO Promoted Intramolecular Oxidative Cyclization of 2‐(Aryl or Alkyl Amino)‐acetophenones for the Synthesis of Isatins.
Authors: Raghavender Reddy M. , Nageswara Rao N. , Ramakrishna K. , Meshram H. M. 
Published: January 2015

AbstractTreatment of acetophenones (I) with iodine in DMSO results in the formation of isatins via a glyoxal intermediate which undergoes intramolecular addition of the amino group to the aldehyde moiety followed by DMSO oxidation.
ChemInform Abstract: [1,3]‐Dipolar Cycloaddition of N‐Aryl Sydnones to Benzothiophene 1,1‐Dioxide, 1‐Cyclopropylprop‐2‐yn‐1‐ol and 1‐(Prop‐2‐ynyl)‐1H‐indole.
Authors: Dueruest Yasar , Sagirli Akin , Kariuki Benson M. , Knight David W. 
Published: January 2015

AbstractA new catalyst‐free protocol using [1,3]‐dipolar cycloaddition reactions of mesoionic N‐aryl sydnones is reported.
ChemInform Abstract: Influence of Catalyst Structure and Reaction Conditions on anti‐versus syn‐Aminopalladation Pathways in Pd‐Catalyzed Alkene Carboamination Reactions of N‐Allylsulfamides.
Authors: Fornwald Ryan M. , Fritz Jonathan A. , Wolfe John P. 
Published: January 2015

AbstractCyclic sulfamides are obtained by Pd‐catalyzed coupling of N‐allylsulfamides with aryl and alkenyl triflates.
ChemInform Abstract: Detritylation of Protected Tetrazoles by Naphthalene‐Catalyzed Lithiation.
Authors: Behloul Cherif , Bouchelouche Kenza , Guijarro David , Najera Carmen , Yus Miguel 
Published: January 2015

AbstractThis method allows the reductive removal of the trityl group from N‐tritylated tetrazoles under non‐acidic conditions without decomposition of the tetrazole.
ChemInform Abstract: 1,3‐Dipolar Cycloadditions of Fluorinated Nitrones with Thioketones.
Authors: Mloston Grzegorz , Obijalska Emilia , Celeda Malgorzata , Mittermeier Verena , Linden Anthony , Heimgartner Heinz 
Published: January 2015

AbstractReadily available fluorinated nitrones (IV) and (XIV) are used in 1,3‐dipolar cycloadditions with thioketones affording 1,4,2 oxathiazolidines in a regioselective manner.
ChemInform Abstract: Broensted Acid Catalyzed, Conjugate Addition of β‐Dicarbonyls to in situ Generated ortho‐Quinone Methides—Enantioselective Synthesis of 4‐Aryl‐4H‐chromenes.
Authors: El‐Sepelgy Osama , Haseloff Stefan , Alamsetti Santosh Kumar , Schneider Christoph 
Published: January 2015

AbstractOptimized conditions which need only little excess of dicarbonyl reactant render possible the access to various title compounds with good to excellent yields and high enantioselectivity.
ChemInform Abstract: Ultrasound‐Assisted One‐Pot Four‐Component Synthesis of Novel 2‐Amino‐3‐cyanopyridine Derivatives Bearing 5‐Imidazopyrazole Scaffold and Their Biological Broadcast.
Authors: Kalaria Piyush N. , Satasia Shailesh P. , Avalani Jemin R. , Raval Dipak K. 
Published: January 2015

AbstractThe majority of the title compounds shows excellent antioxidant activity.
ChemInform Abstract: Asymmetric Synthesis of Substituted NH‐Piperidines from Chiral Amines.
Authors: Gautam Lekh Nath , Su Yijin , Akhmedov Novruz G. , Petersen Jeffrey L. , Shi Xiaodong 
Published: January 2015

AbstractChiral piperidines are prepared in a one‐pot procedure from enones, nitroolefines, and chiral amines.
ChemInform Abstract: Efficient Synthesis of Tetrahydroquinolines from the Reaction of Aldehyde, Aniline, and Alkene under the in situ Redox of SnCl2 and FeCl3.
Authors: Guo Qiaoxia , Teng Weiling , Ren Shenyong , Rao Shasha , Wang Yanqing , Chen Liwei , Shen Baojian , Takahashi Tamotsu 
Published: January 2015

AbstractCompounds (XVI) and (XVIII) are obtained as single diastereomers.
ChemInform Abstract: Synthesis of 3,3‐Disubstituted‐2,3‐dihydroazanaphthoquinones via Simultaneous Alkyne Oxidation and Nitrile Hydration of ortho‐Alkynylarenenitriles.
Authors: Sakthivel Karuppusamy , Srinivasan Kannupal 
Published: January 2015

AbstractOrtho‐Alkynylarenenitriles give 3‐aryl‐3‐hydroxy‐2,3‐dihydroazanaphthoquinones (II), (VI), and (VIII) in the presence of equimolar amounts of palladium acetate.
ChemInform Abstract: Palladium Catalyzed Oxidative Suzuki Coupling Reaction of Indolizine at the 3‐Position Using Oxygen Gas as the Only Oxidant.
Authors: Hu Huayou , Liu Yong , Xu Juan , Kan Yuhe , Wang Chao , Ji Min 
Published: January 2015

AbstractThe applied reaction conditions are not sensible to moisture.
ChemInform Abstract: Catalytic Asymmetric 1,3‐Dipolar [3 + 6] Cycloaddition of Azomethine Ylides with 2‐Acyl Cycloheptatrienes: Efficient Construction of Bridged Heterocycles Bearing Piperidine Moiety.
Authors: Li Qing‐Hua , Wei Liang , Wang Chun‐Jiang 
Published: January 2015

AbstractConjugated cyclic trienes without nonbenzenoid aromatic characteristics are applied as fine‐tunable dipolarophiles in the Cu(I)‐catalyzed asymmetric azomethine ylide‐involved cycloaddition, providing a variety of bridged heterocycles in good yields with exclusive regioselectivity and excellent stereoselectivity.
ChemInform Abstract: A Novel Access to Pyrido[4,3‐d]pyrimidine Scaffold via Staudinger/Intramolecular Aza‐Wittig Reaction of 5‐Acyl‐4‐(β‐azidoalkyl)‐1,2,3,4‐tetrahydropyrimidin‐2‐ones.
Authors: Fesenko Anastasia A. , Shutalev Anatoly D. 
Published: January 2015

AbstractThe general four‐step approach for the synthesis of pyridopyrimidine derivatives involves a final intramolecular Staudinger/aza‐Wittig reaction as the key step.
ChemInform Abstract: Synthesis of N‐(4‐Oxo(thioxo)‐1,3,5‐triazinan‐1‐yl)arylamides Using Samarium‐Containing Catalysts.
Authors: Hairullina R. R. , Geniyatova A. R. , Ibragimov A. G. , Dzhemilev U. M. 
Published: January 2015

AbstractAn effective method for the synthesis of otherwise hardly accessible title triazine derivatives (IV) via a Sm‐catalyzed multicomponent reaction is developed.