bluuebunny/crossref_metadata_2025_split huggingface dataset:
The association between serum vitamin A concentrations and virus hepatitis among U.S. adults from the NHANES database: a cross-sectional study
Authors: Liu Maoxia , Fu Jianlei , Zhang Xuepeng , Fu Qinyi , Ji Yi , Chen Siyuan 
Published: August 2024

ObjectiveAccording to the present study, the relationship between vitamin A (VA) levels and hepatitis virus carriage has been unclear and controversial. This study aimed to determine the potential relationship between serum VA levels and viral hepatitis and to provide ideas for future clinical treatments.MethodsA cross-sectional study was performed using the 2005–2006 and 2017–2018 National Health and Nutrition Examination Survey (NHANES) datasets. Multiple linear regression and logistic regression were adopted to analyze the association between serological hepatitis B surface antigen (HBsAg) or hepatitis C RNA (HCV-RNA) positivity and VA levels. There were 5,351 HBsAg-related responders and 242 HCV-RNA-related responders, including 52 HBsAg (+) and 104 HCV-RNA (+) responders.ResultsCompared with HBsAg (−) and HCV-RNA (−) respondents, HBsAg (+) and HCV-RNA (+) respondents tended to have lower serum VA levels, respectively [1.63 (1.33 ~ 2.01) vs. 1.92 (1.57 ~ 2.34), P &lt; 0.001; 1.54 (1.25 ~ 1.83) vs. 1.78 (1.46 ~ 2.26), P &lt; 0.001]. A greater percentage of responders in the subclinical VA deficiency (SVAD) group were HBsAg (+) and HCV-RNA (+) than were those in the normal VA (VAN) group [2.4% (9/374) vs. 0.9% (43/4977), p = 0.003; 61.5% (16/26) vs. 40.7% (88/215), p = 0.043]. According to the results of the multiple regression analyses of the different models, the serum VA concentration was negatively correlated with HBsAg (+) and HCV-RNA (+) status (β = −0.14, 95% CI = −0.30 to −0.01, p = 0.066; β = −0.29, 95% CI = −0.50 ~ −0.09, p = 0.005, respectively). Compared to those with SVAD, patients with VAN were less likely to be serologically HBsAg (+) or HCV-RNA (+) (OR = 0.53, 95% CI = 0.25 ~ 1.10, p = 0.089; OR = 0.39, 95% CI = 0.18 ~ 0.84, p = 0.016, respectively).ConclusionOur study provides evidence that patients who are HBsAg (+) or HCV-RNA (+) have a high incidence of SVAD. Moreover, HBsAg and HCV-RNA positivity are negatively correlated with VA levels, and patients with SVAD are more likely to carry HBsAg (+) or HCV-RNA (+). These findings suggest that the relationship between hepatitis viruses and vitamin A needs to be validated by more basic studies and clinical large-sample randomized controlled trials to provide ideas for new therapeutic targets.
Absorption of bioactive peptides following collagen hydrolysate intake: a randomized, double-blind crossover study in healthy individuals
Authors: Virgilio Nicolina , Schön Christiane , Mödinger Yvonne , van der Steen Bastiaan , Vleminckx Sara , van Holthoon Frédérique L. , Kleinnijenhuis Anne J. , Silva Catarina I. F. , Prawitt Janne 
Published: August 2024

BackgroundCollagen hydrolysates (CH) in functional foods and supplements are dietary sources of amino acids (AAs) and di-and tripeptides linked to various health benefits. This study aimed to investigate the single-dose bioavailability of skin- and hide-derived CH from fish, porcine and bovine origin with different molecular weights (bovine 2,000 and 5,000 Da).MethodsA randomized, double-blind crossover clinical study was performed with healthy volunteers assessing the plasma concentration of free and peptide-bound hydroxyproline (Hyp) as well as selected peptides reported to be abundantly present in collagen.ResultsThe pharmacokinetic endpoints demonstrated comparable uptake of free Hyp from all CH. A higher amount of total compared to free Hyp indicated the uptake of substantial amounts of Hyp-containing di- or tripeptides.ConclusionIndependently of source and molecular weight, all CH yielded relevant plasma concentrations of the investigated metabolites. Larger studies are needed to estimate an ideal level of selected circulating metabolites needed to trigger distinct physiological reactions in target tissues.
Adaptive responses to elevated CO2 in fruit species with different phloem loading mechanisms
Authors: Davoudi Marzieh , Kalantzis Spyridon , Petridis Antonios 
Published: August 2024

IntroductionIt has been suggested that the mechanism of phloem loading, that is apoplastic or symplastic loading, may affect a plant’s ability to adapt to elevated CO2 levels. Strawberry (Fragaria × ananassa) and tomato (Solanum lycopersicum) are two fruit crops that use different mechanisms to load sugars into the phloem – the former symplastically and the latter apoplastically – yet both species can increase their yields when grown in a CO2-enriched environment. In this study, we subjected strawberry and tomato plants to long-term CO2 enrichment to determine the morphological and physiological adaptations that enable them to increase their yields in response to higher CO2 levels.MethodsTransplanted tomato and strawberry plants were subjected to ambient (400 ppm) and elevated (800 ppm) CO2 for three months. We examined various parameters associated with growth, yield, photosynthesis, and carbon allocation by means of phenotyping, gas exchange analysis, and 13C labelling combined with isotope ratio mass spectrometry.ResultsWe found that CO2 enrichment promoted growth and reproductive development in both species, resulting in more flowers per plant (tomato and strawberry), larger crown (strawberry), and, eventually, higher yields. Gas exchange analysis and A/ci curves revealed that elevated CO2 increased carbon assimilation rate in strawberry, but not in tomato – the latter being limited by Rubisco’s carboxylation efficiency. Finally, whereas both species prioritized fruit development over the development of other sink organs, they were both limited by carbon export at elevated CO2, since new photoassimilates were equally distributed to various sinks between CO2 treatments.DiscussionThe findings suggest that both species will benefit from future increases in CO2 levels and support current glasshouse practices entailing CO2 enrichment. Those benefits probably stem from an enhanced performance of both species at early developmental stages, as differences in carbon assimilation rate (tomato) and carbon allocation between treatments at late developmental stages were absent. Moreover, crop adaptation to elevated CO2 seems to depend on the ability of each species to respond to elevated CO2, rather than on the phloem loading mechanism per se.
Uncovering novel genes for drought stress in rice at germination stage using genome wide association study
Authors: Nyasulu Mvuyeni , Zhong Qi , Li Xiansheng , Liu Xu , Wang Zhengjie , Chen Liang , He Haohua , Bian Jianmin 
Published: August 2024

IntroductionBreeding rice with drought tolerance for harsh environments is crucial for agricultural sustainability. Understanding the genetic underpinnings of drought tolerance is vital for developing resilient rice varieties. Genome-wide association studies (GWAS) have emerged as pivotal tools in unravelling the complex genetic architecture of traits like drought tolerance, capitalizing on the natural genetic diversity within rice germplasm collections.MethodsIn this study, a comprehensive panel of 210 rice varieties was phenotyped over ten days in controlled conditions, subjected to simulated drought stress using 20% PEG 6000 in petri dishes. Throughout the stress period, crucial traits such as germination percentage (GP), germination rate index (GRI), mean germination time (MGT), and seedling percentage (SP) were meticulously monitored.ResultsThe GWAS analysis uncovered a total of 38 QTLs associated with drought tolerance traits, including novel loci likeqMGT-5.2, qSP-3, qSP7.2, andqGP-5.2. Additionally, RNA-seq analysis identified ten genes with significant expression differences under drought stress conditions. Notably, haplotype analysis pinpointed elite haplotypes in specific genes linked to heightened drought tolerance.DiscussionOverall, this study underscores the importance of GWAS in validating known genes while unearthing novel loci to enrich the genetic resources for enhancing drought tolerance in rice breeding programs.
A case-crossover study of ST-elevation myocardial infarction and organic carbon and source-specific PM2.5 concentrations in Monroe County, New York
Authors: Zhao Tianming , Hopke Philip K. , Utell Mark J. , Croft Daniel P. , Thurston Sally W. , Lin Shao , Ling Frederick S. , Chen Yunle , Yount Catherine S. , Rich David Q. 
Published: August 2024

BackgroundPrevious work reported increased rates of cardiovascular hospitalizations associated with increased source-specific PM2.5 concentrations in New York State, despite decreased PM2.5 concentrations. We also found increased rates of ST elevation myocardial infarction (STEMI) associated with short-term increases in concentrations of ultrafine particles and other traffic-related pollutants in the 2014–2016 period, but not during 2017–2019 in Rochester. Changes in PM2.5 composition and sources resulting from air quality policies (e.g., Tier 3 light-duty vehicles) may explain the differences. Thus, this study aimed to estimate whether rates of STEMI were associated with organic carbon and source-specific PM2.5 concentrations.MethodsUsing STEMI patients treated at the University of Rochester Medical Center, compositional and source-apportioned PM2.5 concentrations measured in Rochester, a time-stratified case-crossover design, and conditional logistic regression models, we estimated the rate of STEMI associated with increases in mean primary organic carbon (POC), secondary organic carbon (SOC), and source-specific PM2.5 concentrations on lag days 0, 0–3, and 0–6 during 2014–2019.ResultsThe associations of an increased rate of STEMI with interquartile range (IQR) increases in spark-ignition emissions (GAS) and diesel (DIE) concentrations in the previous few days were not found from 2014 to 2019. However, IQR increases in GAS concentrations were associated with an increased rate of STEMI on the same day in the 2014–2016 period (Rate ratio [RR] = 1.69; 95% CI = 0.98, 2.94; 1.73 μg/m3). In addition, each IQR increase in mean SOC concentration in the previous 6 days was associated with an increased rate of STEMI, despite imprecision (RR = 1.14; 95% CI = 0.89, 1.45; 0.42 μg/m3).ConclusionIncreased SOC concentrations may be associated with increased rates of STEMI, while there seems to be a declining trend in adverse effects of GAS on triggering of STEMI. These changes could be attributed to changes in PM2.5 composition and sources following the Tier 3 vehicle introduction.
Surface Modification of AM60 Mg-Al Alloy with Vanadium and V2O5 Sputtered Deposits: Activity in Marine Ambience
Authors: Sánchez Gerardo , Veleva Lucien , Flores Eduardo 
Published: August 2024

Vanadium (~450 nm) and V2O5 (~350 nm) were deposited by DC magnetron sputtering on an AM60 substrate to improve its degradation resistance in marine ambience. According to Raman and XPS analysis, the vanadium nanofilm mainly consists of amorphous V2O3, while V2O5 comprises two sheets of VO5 and VO4 units. After 30 days of immersion of the coated AM60 in a marine model solution (SME), the shift of the pH of the SME to more alkaline values was less pronounced for V2O5-AM60 because of the HCl acid formation during the partial dissolution of V2O5 in the presence of NaCl, and thus, a higher concentration of Mg2+ ions ~100 mg L-1 was released from the Mg (AM60) matrix. The lower concentration of ~40 mg L-1 from the V-AM60 surface was attributed to the possible intercalation of the released Mg ions (cations) into the conductive tunnels of V2O3 as the main component of the vanadium sputtered deposit. This oxide has been reported as a material for high-capacitive energy storage. In this way, the V-deposit provided longer partial protection for the AM60 surface (Mg matrix) from localized pitting attacks.
Wood Mice Utilize Understory Vegetation of Leafless Dead Dwarf Bamboo Culms as a Habitat and Foraging Site
Authors: Kajita Rui , Kajimura Hisashi 
Published: August 2024

In this study, we conducted a field survey in Aichi Prefecture, central Japan, to clarify whether rodent activity is affected by the presence or absence of dead culms of the dwarf bamboo Sasa borealis, a species characterized by a 120-year cycle of large-scale flowering, seeding, and dying. We found that a relatively larger number of wood mice, Apodemus speciosus and Apodemus argenteus, were caught using Sherman live traps in areas with dead S. borealis culms than in areas lacking the culms, thereby indicating that S. borealis culms, even if dead and leafless, can function as shelters in which the mice can evade predation. However, in the years when A. speciosus was abundant, A. argenteus avoided areas inhabited by A. speciosus and was restricted to areas lacking dead culms, which were devoid of shelter. A feeding experiment using Castanea crenata acorns clearly revealed that a larger number of acorns were foraged by mice in areas containing dead culms. Moreover, in the area with dead culms, the mice preferentially removed sound acorns prior to taking acorns that had been vacated by infesting moth larvae. These findings indicate that the shelter function of dead culms enables mice to carefully select sound acorns, which are nutritionally more beneficial than those that have been infested by moth larvae.
A experiência do Projeto Escola Verde: Educação Socioambiental em um município do Ceará
Authors: Barros Cristiane Saboia , Aguiar Welesson Portela de , Uchoa Elenilton Bezerra , Barbosa Pablo Gordiano Alexandre 
Published: August 2024

O estudo tem por objetivo descrever um projeto de Educação Ambiental denominado Escola Verde desenvolvido no âmbito do Programa de Educação Socioambiental do município de Sobral, Ceará. Acerca dos procedimentos metodológicos, o estudo possui uma abordagem qualitativa, estudo de caso e documental, realizado a partir de pesquisas no Google Acadêmico e no buscador Google. Os resultados do estudo sugerem que o projeto Escola Verde, desenvolvido e implementado em 2020 pela Prefeitura Municipal de Sobral, é um bom exemplo colocado em prática. Embora conduzido de maneira remota, teve uma atuação relevante junto à comunidade escolar, principalmente ao evidenciar os aspectos socioambientais próprios da cidade de Sobral.
КӨРКӨМ ОБРАЗДЫН ФИЛОСОФИЯЛЫК МАҢЫЗЫ
Authors: Бекбоев А.А. , Карабукаев К.Ш. 
Published: August 2024

В статье проанализирована сущность понятий «слово» и «литература» в контексте современной философской метафизики. Краткая экспликация статьи: понятие «СЛОВО» в значении «ЛОГОС», как обобщенное логическое явление означающего «разумение жизненного начала», по определению составляет фундаментальный постулат (символ) и философии, и литературы. Философия и литература неразрывно связаны по смыслу и содержанию, природе, познавательному потенциалу, так как оба эти феномена являются абстракцией мироустройства (мироздания): философия – через понятия, а литература – через художественные средства (образ, типичность, художественный характер и т. д.) обобщает явления, события, процессы мироздания, жизнедеятельности.
Макалада азыркы философиялык метафизиканын алкагында “сөз” жана “адабият” түшүнүктөрүнүн маңызы анализденет. Макаланын кыскача экспликациясы: ”сөз” түшүнүгү “жашоо-турмуштун башатын аңдоо” деген маанидеги логикалык жалпылоо катары философиянын да, адабияттын да фундаменталдуу постулатын түзөт; философия жана адабият табияты, мазмуну жана мааниси боюнча дүйнөтүзүлүштүн абстракциясы катары бири-бири менен тыгыз байланышта: философия түшүнүк аркылуу, адабият көркөм каражаттар (образ, типтүүлүк, көркөм мүнөз) аркылуу дүйнөтүзүлүштүн, жашоо турмуштун, окуяларды, кубулуштарды жалпылайт.
The article analyzes the essence of the concepts of “word” and “literature" in the context of modern philosophical metaphysics. Brief explication of the article: the concept of “WORD“ in the meaning of ”LOGOS", as a generalized logical phenomenon meaning “understanding of the life principle”, by definition constitutes a fundamental postulate (symbol) of both philosophy and literature; philosophy and literature are inextricably linked in meaning and content, nature, cognitive potential, since both these phenomena are abstraction of the world order (universe): philosophy – through concepts, and literature – through artistic means (image, typicality, artistic character, etc.) generalizes phenomena, events, processes of the universe, vital activity.
Makna Keris Jawa dan Upaya Pelestariannya Dalam Perspektif Sosiologi : Studi pada Paguyuban Tosan Aji Panji Patria
Authors: Muspita Novi Catur , Sudiasmo Fandi , Pradeta Fandu Dyangga 
Published: August 2024

Keris is a cultural product that holds a million mysteries to be guarded and preserved, keris has been recognized by UNESCO, every Friday Legi the Blitar community gathers there is a keris exhibition at (PIPP) Blitar. The aims of this study are: (1) to identify and analyze the meaning of Keris Jawa in a sociological perspektive, (2) to identify and analyze conservation efforts it, (3) to identify and analyze the supporting and inhibiting factors in the conservation of it: a study of the Tosan Aji Panji Patria community. The research method uses qualitative research. The results of the study: (1) The meaning of Keris Jawa ; (a) Keris as accessories for ceremonial clothing during cultural ritual ceremonies, (b) Keris as a souvenir, (c) Keris has meaning high philosophy, namely about faith in God and procedures for holding, opening, and inserting a keris, (e) learning about metal, copper, steel and meteors as well as iron science, (2) Efforts to preserve Keris Jawa: (a) routine activities every Friday Legi, namely the keris exhibition, (b) socialization of keris as artistic and cultural value at discussion events (c) the joint commitment of the government and the community to preserve it, (3) Supporting factors in the effort to preserve Keris Jawa: ( a) The Blitar Government supports and facilitates Keris exhibition at PPIP, (b) the enthusiasm of the community is very high at every Keris exhibition event, while Covid-19 pandemic, activities in limit.
The Awareness of Generation Z About Nature, Sex and Gender
Authors: Siswati Endah , Yefi Dyan Nofa Harumike  , Fera Tara Batari  
Published: August 2024

The patriarchal culture that is socialized and internalized from generation to generation creates misunderstandings about the nature of men and women. This misunderstanding is also related to the confusion in the meaning of society about the concept of sex and gender. Efforts to straighten understanding and build public gender awareness have long been promoted. How is the result? How is the awareness or understanding of Generation Z about the concepts of sex and gender and the nature of men and women? This research was conducted to answer this question. The research method used is descriptive quantitative method. Researchers calculate, juxtapose and compare the percentage of respondents' answers, to draw concepts or conclusions with logical and critical analysis. The population of this study were social and political students at the Balitar Islamic University. The research sample was taken using quota sampling, and determined 100 male students and 100 female students as respondents. The results of this study indicate that: 1) respondents' awareness of the concept of sex or gender is classified as good, but respondents' awareness of the concept of gender is still below the average, 2) the majority of respondents are confused in distinguishing the concepts of sex and gender, and 3) the majority of respondents are wrong in interpreting the essential nature of men and women. This research can be used as a reference for government and non-government institutions in conducting socialization to build gender awareness of the younger generation.

Keywords: feminism, gender awareness, patriarchy, women, men
PENGARUH PENGGUNAAN TEPUNG YANG BERBEDA TERHADAP KUALITAS ORGANOLEPTIK DAN KIMIA BAKSO DAGING SAPI ONGOLE BETINA AFKIR (The effect of using different flour on organoleptic and chemical quality of meatball of ongole beef culled)
Authors: Maubere Devan Oscalis , Noach Yakob R. , Malelak Gemini E. M. 
Published: August 2024

Flour is one of ingredients used in processing meatballs. Each type of flour has particular characteristics that could influence characteristics of the meatballs produced. This study aims to find out how the effect of using different flour on organoleptic and chemical quality of bakso of ongole beef culled. Completely randomized design (CRD) with 4 treatments and 3 replications used in this experiment. The treatments consisted of P0 = 100% Tapioca, P1 = 70% Tapioca + 30% Taro flour, P2 = 70% Tapioca + 30% Purple sorghum flour, and P3 = 70% Tapioca + 30% Purple yam flour. The parameters measured including water content, protein content, fat content, and organoleptic quality including taste, texture, aroma and color. Analysis of variance results showed that the treatments had a highly significant effects (P<0,01) to water content, protein, fat, taste, color, texture, and scent. It could be concluded that using different flours produces bakso with different chemical qualities and organoleptic. Meatball that produced at P0, P1, P2, and P3 treatments had water content while protein content not achieve SNI standard. For organoleptic test, the best treatment was P1 treatment because it had highest rating score in the taste, color, texture, and scent section, when compared to the P2 and P3 treatments.
Studi Epistemologi Hukum Islam dalam Konteks Fatwa Majelis Ulama Indonesia
Authors: Firdaus Syarif , Achmad Mukhsin 
Published: August 2024

This study aims to explore the epistemological foundations underlying the fatwa (religious decree) formulation processed by the Indonesian Council of Ulama (MUI) and analyze the dynamics of Islamic legal epistemology in the Indonesian context. Using a qualitative method with a content analysis and hermeneutical approach, this study examines MUI's fatwas published in the last decade, with contemporary Islamic epistemology theory and the maqashid sharia approach as the analytical framework. The research findings show that MUI applies an eclectic epistemological approach, integrating the bayani, burhani, and irfani methods in the fatwa establishment process. There is a significant effort to contextualize Islamic law with the realities of Indonesian society, reflected in the use of the principles of maslahah (public interest) and 'urf (local customs). MUI's collective ijtihad (independent reasoning) practice enriches the epistemological basis of the fatwas, but also poses challenges in synchronizing various perspectives. The novelty of this research lies in the comprehensive analysis of the dynamics of Islamic legal epistemology in MUI's fatwas in the digital era, which has not been widely explored before. This study reveals the flexibility and adaptability of Islamic legal epistemology in addressing contemporary issues, while also identifying the methodological challenges faced. The research recommends the development of a more systematic and transparent epistemological framework in the fatwa formulation process. Further studies are suggested to explore the impact of MUI's fatwas on Indonesia's socio-political dynamics and analyze the role of digital technology in the transformation of religious authority.
Key words: epistemology; MUI, Islamic law; fatwa; legal