bluuebunny/crossref_metadata_2025_split huggingface dataset:
P-333 BRUCELLOSIS AMONG LABORATORY WORKERS: A PERSISTENT CONCERN
Authors: Triki Amira , Ayadi Abir , Jlassi Olfa , Ayari Sihem , Abdelmlak Rym , Magroun Imene 
Published: July 2024

Abstract

Introduction
In Tunisia, brucellosis is endemic in certain regions, especially in rural areas. It is an occupational disease, primarily affecting professionals in contact with infected animals and laboratory workers. The aim of this study was to describe the circumstances surrounding work- related accidents occurring in laboratory workers due to inhalation of Brucella.

Methods
A retrospective descriptive study involving three laboratory workers who consulted the occupational department in February 2023 to report work-related accidents following accidental inhalation of Brucella. Data collection was done from medical records. A visit to the microbiology laboratory was conducted.

Results
The study included two women and one man, aged 28, 37, and 42 years. They worked as physician, laboratory technician, and nurse. All three laboratory workers had handled positive blood culture for Brucella. Two laboratory workers remained asymptomatic, while one developed a sudorificalgic fever. The workplace investigation revealed the absence of hoods and respiratory masks. The patients were referred to the infectious diseases department, where chemoprophylaxis with Rifampicin and Doxycycline was prescribed for three weeks for the first patient. For all patients, serological tests (Wright and Rose Bengal serologies) were conducted after two weeks to one month, and the results were negative. The work-related accidents were reported.

Discussion
This study highlights the work-related accidents in laboratory workers due to the inhalation of Brucella and the importance of protective equipment in bacteriology laboratories. Post- exposure prophylaxis is discussed.

Conclusion
The development of clinical practice guidelines for employees exposed to Brucella is an essential tool for occupational health physicians.
O-189 IMPLEMENTATION OF EXPOSURE-RISK RELATIONSHIPS AS BASIS FOR DIFFERENTIATED PROTECTIVE MEASURES
Authors: Pallapies Dirk , Welge Peter , Bruening Thomas 
Published: July 2024

Abstract

Introduction
In Germany, exposure-risk relationships for about 30 carcinogenic substances without effect threshold for carcinogenicity have been derived during the last decade. A tolerable concentration and an acceptable concentration associated with risk levels of 4:1,000 and 4:10,000 (target 4:100.000; additional lifetime cancer risk after exposure throughout the whole working life) define three workplace concentration ranges (“red”, “yellow”, “green” area, corresponding to high (not tolerable), medium (transiently tolerable), low (acceptable) risk, respectively).

Methods
Working groups of stakeholders in occupational safety and health developed a refined guidance for the derivation of the exposure-response relationships. Additionally, differentiated measures of the occupational health hygiene strategy will be characterized more in detail, depending on the risk levels that determine which protective measures will have to be applied in order to reduce the cancer risk for the workers.

Results
The refined guidance explains in detail how to select and assess both the relevant human and animal data, how to combine human and animal data and how to calculate the concentrations associated with the risk levels mentioned above. Examples of carcinogenic substances for which exposure-risk relationships exist are asbestos, benzene, ethylene oxide or metals such as cadmium, cobalt, nickel.

Discussion and Conclusion
This risk-based concept has been proven practicable and effective. While a similar concept does exist already in the Netherlands, it has now also been introduced to the European Union. A harmonized approach with an agreement about tolerable and/ or acceptable risks would enable an adequate protection of workers against carcinogenic risks on an EU-wide level.
P-349 OCCUPATIONAL EXPOSURE TO PESTICIDES AND THEIR IMPACT ON ENDOCRINE AND EPIGENETIC PROFILES OF FARMWORKERS IN MOROCCO: A STUDY PROTOCOL
Authors: Chbihi Kaoutar , Menouni Aziza , Berni Imane , Abou-Said Said , Chetouani Hala , Verscheure Eline , Lebegge Robin , Poels Katrien , Ghosh Manosij , Vanoirbeek Jeroen , Duca Radu-Corneliu , IDEWE Lode Godderis , Jaafari Samir El 
Published: July 2024

Abstract

Introduction
Pesticides are commonly used chemicals to improve agricultural yield and face farming challenges. However, these compounds might significantly affect the human health. In Morocco, pesticides are increasingly used in agriculture and start to constitute a major concern for farmers’ and farmworkers’ health, especially in rural areas where safety guidelines are weakly respected. Therefore, we aim in this study to assess the exposure of farmers and farmworkers to pesticides and evaluate the impact on their endocrine and epigenetic profiles.

Methods
This ongoiong study takes place in Meknes prefecture and is conceived based on an analytical cross-sectional design, consisting in exposed and control groups. 200 healthy and volunteer participants are asked to enroll the study following a clear informed consent, to answer a questionnaire on pesticide usage, exposure and lifestyle and to provide blood and urine samples. First, a set of 7 organophosphate pesticide metabolites will be quantified in urine using solid phase extraction and liquid chromatography methods being developed. Then, blood will serve in measuring thyroid and reproductive hormones in serum, in addition to global DNA methylation markers and specific hormones receptros genes in the whole blood.

Results
The results are expected to explain the association that might exist between pesticide exposure and epigenetic and/or endocrine alterations from one hand and the importance of Biomonitoring in preserving the health of Moroccan populations in occupational settings.

Discussion and conclusion
Finally, this study will help to shed light on the potential health risks in farmworkers related to pesticide usage and will promote knwoledge and safety elaboration to protect this range of population.
P-355 BIOMONITORING OF GLUTATHIONE AS POTENTIAL BIOMARKER FOR RISK ASSESSMENT OF WORKERS EXPOSED TO COMPLEX MIXTURES
Authors: Creta Matteo , Moldovan Horatiu , Farczadi Lenard , Ani Maria Mirela , Buonuario Flavia , Tranfo Giovanna , Duca Radu 
Published: July 2024

Abstract

Introduction
Glutathione redox couple (GSH/GSSG) plays a fundamental role in different detoxification pathways and regulation of oxidative stress. Exposure to metals and aromatic organic compounds (AOC) was proven to induce an imbalance of GSH/GSSG, triggering possible health effects. In this study, the ratio of GSH/GSSG concentrations were measured as potential tool for risk-assessment of workers exposed to complex mixtures.

Methods
Exposed workers (n=75) of two coalmines were recruited together with non-occupationally exposed people (n=20). Blood samples were collected to determine GSH/GSSG concentrations; exposure was assessed through the quantification of metals in blood and AOC urinary metabolites, such as SPMA and SBMA; inhalation exposure was evaluated collecting air samples for metals and AOC.

Results
The quantification of metals in blood highlighted a higher exposure to metals for mineworkers (Pb: 27 µg/L) than controls (Pb: 11 µg/L). Similar differences were observed for urinary SPMA and SBMA, showing higher concentrations in mineworkers (SPMA: 0.81 µg/L; SBMA: 11.4 µg/L) than controls (SPMA: 0.09 µg/L; SBMA: 3.58 µg/L). These results were confirmed by the analysis of environmental samples, which showed an overall higher exposure for mineworkers A significant depletion of GSH/GSSG ratio was observed between mineworkers (356±21) and controls (1057±92), showing a negative correlation between GSH/GSSG ratio and the blood concentrations of Pb (rspearman=-0.49), Cd (rspearman=-0.35) and Cr (rspearman=-0.25) for the entire studied population. Poor correlation was found between urinary SPMA/SBMA and GSH/GSSG ratio.

Discussion and Conclusion
These findings confirm the involvement of GSH/GSSG in several detoxification pathways following mixtures exposure, strengthening the approach of effect-biomarkers determination for risk-assessment purpose.
P-370 THE BURTON’S LINE AND THE ROLE OF 25(OH)D IN LEAD-EXPOSED WORKERS
Authors: Prodia Cesio Vidiar , Fuk Liem Jen , Mulyana Mulyana , Pangaribuan Bertha , Mansyur Muchtaruddin , Mulyana Mulyana , Fuk Liem Jen , Vidiar Cesio , Pangaribuan Bertha 
Published: July 2024

Abstract

Introduction
Occupational lead exposure is one of the significant sources of lead poisoning. The Burton’s line, a bluish-grey line on the gum is a clinical sign found in chronic lead poisoning. Vitamin D is known to have antioxidant effects, but the role of antioxidants in lead poisoning is remain unclear. Our study aimed to explore the relationship between Burton’s line and blood lead level (BLL) and BLL/25(OH)D ratio.

Methods
A total of 71 male workers occupationally exposed to lead in Java, Indonesia, participated in this cross-sectional study. Participants were interviewed for their characteristics and underwent a physical examination. The venous blood samples were taken from all subjects. BLL was measured using ICPMS and serum 25(OH)D was measured using the ECLIA.

Results
Burton’s line was found in 13 (18.3%) participants. Following the Mann-Whitney U test, the median (min-max) of BLL (11.76 (5.08-29.67) μg/dL) and BLL/25(OH)D ratio (0.47 (0.23-1.99)) in Burton’s line group was higher (p&lt;0.05) than in non-Burton’s line group (6.72 (1.17-43.94) μg/dL) and 0.34 (0.05-3.14), respectively.

Discussion
Our findings confirmed previous results that lead exposure is the risk factor in the formation of Burton’s line. A higher BLL/25(OH)D ratio among those with Burton’s line indicated that a higher lead exposure induced lower 25(OH)D concentrations or less antioxidant activity.

Conclusion
Burton’s line may be found in chronic heavy metal exposure. 25-OH vitamin D may interact with lead deposition in soft tissues. Keywords: Blood lead levels, Burton’s line, BLL/25(OH)D ratio
O-195 EVOLUTION OF OCCUPATIONAL HEALTH IN A DEVELOPING COUNTRY FROM THE LENS OF AN INDUSTRIAL PHYSICIAN
Authors: Pingle Shyam 
Published: July 2024

Abstract

Introduction
India contributes a staggering 25% of global working population, thanks to its population and demographics. Occupational health in India has grown and evolved over last 40 years which coincided with my career as an Industrial Physician and later as an academician.

Methods and results
Evolution of modern occupational health in India is heavily influenced by three events: 1. The infamous ‘Bhopal Gas Disaster’ in December 1984 claimed more than 25000 lives. It led to major changes in the legislations and statutory requirements for the industry in general and chemical industry in particular. This led to focus on regular medical surveillance. 2. The economic crisis in 1991, led to liberalization and attracted global corporations to India who brought global health and safety standards giving a boost to further development of workplace exposure monitoring. Establishment and expansion of service industry in India also coincided with proactive ‘Workplace Wellness’ initiatives to retain talent and promote employee health and productivity. 3. Adoption of BOHS (Basic Occupational Health Services) by Indian Association of Occupational Health since 2008 leading to widespread awareness and advocacy among stakeholders.

Discussion and Conclusion
The specialty of OH has transitioned from welfare and statutory requirements to support productivity and ensure longer workability of employees. However, India still faces challenges such as lack of awareness and enforcement in the small and medium enterprises, Capacity building in occupational health and lack of occupational health data. Major evolution is now expected with imminent changes in legislation and national policy on OSH covering non-hazardous industries and workplaces in the ambit of law.
O-196 NATIONAL PROGRAMMES FOR THE ELIMINATION OF SILICOSIS IN THE NON-MINING INDUSTRY: A SCOPING REVIEW
Authors: Ndlovu Ntombizodwa , Volmink Odette , Sepirwa Edward , Achayo Meckie 
Published: July 2024

Abstract

Introduction
Experiences from countries, e.g., Switzerland, Germany, Finland and France, demonstrated that silicosis incidence reduction is possible. In 1995, the ILO/WHO launched the Global Programme for the Elimination of Silicosis (GPES) to support National Programmes for the Elimination of Silicosis (NPES) by member countries for elimination of silicosis by 2030. We explored the implementation, enablers and barriers of NPES in the non-mining industry globally.

Methods
In this scoping review, PubMed, Scopus, Web of Science and the Cochrane Library and several institutional websites were searched for scientific and grey literature. Documents in English on NPES published from 1995 to 2021 were included.

Results
Eleven of 1277 documents met the eligibility criteria and were reviewed (2 journal papers, 3 reports, 5 slide presentations and 1 fact sheet). Seven were dated 2005 and four from 2010 to 2021. The reports covered nine countries: Brazil, Chile, China, India, Peru, South Africa, Thailand, Turkey and Vietnam. Enabling strategies were international and national collaborations, capacity building, policy development, enforcement, and surveillance and research. Barriers included inadequate political will, financial resources, lack of knowledge, access to information, reporting and poor enforcement of regulations.

Discussion
The sparse reporting on NPES implementation and evaluation suggests loss of momentum of the GPES and a shift of focus to other hazards. Improved leadership, awareness, regular reporting, collaboration and sharing of best practices should contribute to attainment of the elimination targets.

Conclusion
Silicosis elimination remains a priority due to its emergence in new (e.g., artificial stone) and old (e.g., coal mining) industries and resurgence in some countries.
O-204 CLOSING THE GAPS: DID THE ONLINE PHYSIOTHERAPEUTIC AND ERGONOMIC INTERVENTIONS HAVE AN IMPACT ON THE INFORMATION TECHNOLOGY EMPLOYEES IN A DEVELOPING COUNTRY?
Authors: Rajkumar Joshua , Biyala Neha , Shekar Monisha , Rajendran Divya , Ghimire Keshika , Kausar Shagufta , BK Sushma 
Published: July 2024

Abstract

Introduction
Onsite clinics play a crucial role in the provision of Occupational health services through Physiotherapists trained in Ergonomics for managing Work-related Musculoskeletal Disorders (WRMSDs), which acts as a substantial source of the economic drain in the Information Technology (IT) sector. However, during and post the COVID-19 pandemic the onsite Physiotherapy cum Ergonomic services moved online for most of the IT companies.

Methods
A retrospective analysis was done on the data gathered from 2020 to 2022 in IT companies, where online services of physiotherapists trained in ergonomics were done to address the WRMSDs for the employees. The data collected were demographic details, Nordic Musculoskeletal Pain Questionnaire (NMQ), and Visual Analog Scale (VAS) for measuring pain. The employees who had pain/discomfort consulted the Physiotherapist online and based on the severity, activity modifications, graded exercises and self-soft tissue releases, rest, icing/hot packs, supportive braces, and postural/ergonomic modifications were recommended. Followup consultation was done weekly and 1&3 months later.

Results
Among the 775 employees analyzed, the majority were males (72%) with a median age of 38.5 years reporting a median VAS 6. Most reported were low back pain (64%). 85% of the employees had significant pain reduction (P&lt;0.05). Activity modifications (85%) and Graded exercises (90%) were the predominant interventions given online. Only 8% of the employees had a recurrence in the 3rd month follow-up.

Discussion and Conclusion
Online interventions by Physiotherapists trained in ergonomics had a significant impact on the outcomes of pain among IT employees, which can pave the way for closing the gaps in managing WRMSDs.
P-373 HEART HEALTH SCORE (HHS): PROMOTING CARDIOVASCULAR HEALTH IN CHILEAN MINING INDUSTRY USING A TAILORED DIGITAL REPORT
Authors: Mendez Jose , Rio Antonia Del , Gonzalez David 
Published: July 2024

Abstract

Introduction
Cardiovascular diseases are the leading cause of mortality and morbidity in Chile. Raising awareness in mining workers requires targeted promotional and preventive interventions.

Methods
Clinical data from occupational medical assessments of 2597 workers from a Chilean copper mining company (75% of headcount) conducted during 2021/22 were obtained and processed using WHO 2019 cardiovascular risk scale. After signing an informed consent, automated digital Heart Health Score (HHS) reports were sent to each worker providing detailed feedback on individual cardiovascular risk and tailored advice on healthy lifestyle.

Results
2597 workers received a personalized HHS report (87.1% male, mean age 44.1 years (range 22-70)). Cardiovascular risk distribution was very low (64%), low (30%), moderate (5%) and severe (1%). Prevalence of hypertension (5.3%), obesity (23.4%) and tobacco consumption (24%) were significantly lower than Chilean general population. Mean BMI (body mass index) was 27.7. Each report included tailored recommendations related to tobacco use, total cholesterol level and blood pressure.

Discussion
Mining workers in Chile are known to have lower prevalence of cardiovascular risk factors, probably due to healthy worker effect (occupational fitness-for-duty requirements). Using data from occupational health medical assessments to give individual and periodic feedback on cardiovascular risk might increase awareness and determine trigger actions (e.g.: referral to medical provider).to treat existing diseases or control risk factors.

Conclusion
Heart Health Score (HHS) is innovative digital tool to provide individual feedback on cardiovascular health to Chilean mining workers. An upgraded version is being designed using Framingham score and adding specific nutritional and physical activity recommendations.
O-217 ESSENTIAL TREMOR IN NURSING STAFF: A CASE REPORT
Authors: Mazroui Imane , Wifaq Kamal , Soltani Sara , Benjdiya Malak , Norredine Doha , El Kholti Abdeljalil 
Published: July 2024

Abstract

Introduction
Essential tremor is one of the most common neurological disorders, affecting approximately 0.9% of the general population. It can be exacerbated by certain work-related factors, often leading to an inevitable impact on work quality of life. The objective of this study is to assess the impact of essential tremor on the activities of healthcare personnel in order to propose appropriate preventive measures.

Materials and Methods
This study is based on the health status analysis of a nurse working in the stomatology and maxillofacial surgery department at Ibn Rochd University Hospital in Casablanca. The assessment includes evaluating physical workload using the INRS grid and perceived stress using the PSS-14 score.

Results
After a specialized medical evaluation, the nurse was diagnosed with essential tremor. The analysis of the physical workload using the INRS grid revealed a moderate score. The perceived stress, evaluated by the PSS-14, indicated a moderate stress level with a score of 24. Consequently, no incompatibility between the job and health status was observed, and no specific adjustments were recommended.

Discussion
Tremors among nursing staff have been reported in the literature before. This condition can impact professional activities, sometimes requiring adaptations such as flexible work schedules or frequent breaks. The involvement of the occupational health physician is crucial as it allows for evaluating the compatibility of health conditions with professional activities. In our case, no adjustments were needed.

Conclusion
Collaboration between the occupational health physician and the specialist is essential to assess and address specific pathological cases occurring among healthcare personnel.
O-235 PSYCHOLOGICAL IMPACT OF REMOTE WORK ON EMPLOYEES IN THE GREATER CASABLANCA REGION, MOROCCO
Authors: Touil Soukaina , Rifak Nada 
Published: July 2024

Abstract

Introduction
Due to the COVID-19 pandemic, many Moroccan companies have continued to embrace remote work, resulting in a profound transformation of the nature of work and telecommuters. The objective of our work is to describe the psychological impact associated with the implementation of remote work in companies within the Greater Casablanca region.

Methods
We conducted a cross-sectional study between August 1st and September 1st, 2022, involving thirty semi-structured interviews with a population of employees who had been engaged in remote work for a minimum of six months in the Greater Casablanca region.

Results
We observed that remote work enables improved autonomy at work for 86.6% and a sense of tranquility for 56.6% of the surveyed employees. Approximately 66.6% of telecommuters find that their positions are either well-suited or even better than in-person. Among these, 75% emphasize the crucial role of the occupational health service in implementing remote work.

Discussion
Overall, the findings of this study demonstrate a positive impact on the psychological well-being and quality of life of the surveyed employees.

Conclusion
Remote work offers advantages to the workers who experience its implementation. It provides telecommuters with the opportunity to navigate professional reorganization and acquire new skills. However, remote work can also have adverse effects if not overseen by a preventive program, which should be established by the employer.
O-241 OCCUPATIONAL TUBERCULOSIS: A CASE REPORT
Authors: Es-Saadi Kawtar , Tahri Loubna , Wifaq Kamal , Benjdiya Malak , Hammal Asmaa , El Kholti Abdeljalil 
Published: July 2024

Abstract

Introduction
Pulmonary tuberculosis represents a major issue in the workplace. This work highlights infectious risks among healthcare workers, particularly occupational tuberculosis, and emphasizes the importance of preventive measures to minimize these risks.

Methods
This study is based on a case of occupational tuberculosis detected in a resident in visceral surgery at Ibn Rochd University Hospital in Casablanca. The evaluation of his health condition was based on clinical examinations, biological and radiological investigations.

Results
The presumption of the origin of tuberculosis in this resident is based on the disease’s history, notably a symptomatology characterized by night sweats and asthenia and weight loss that occurred three weeks after being in contact with a patient treated for peritoneal tuberculosis in his department. This led to a consultation and the initiation of antitubercular treatment. A decision was made to grant the resident a medium-term medical leave and a procedure to declare it as an occupational disease was initiated.

Discussion
Tuberculosis is endemic in Morocco, with 35,000 new cases reported annually and 10.4 million new cases worldwide. Investigation in the workplace regarding the index case is not yet mandatory in contrast to family investigations. Hence, the crucial role of the occupational physician who should direct towards a professional investigation for screening. Following this case, a protocol for managing cases of hospital-acquired occupational tuberculosis was developed by our department.

Conclusion
Raising awareness among healthcare workers is essential to take necessary preventive measures when in contact with a tuberculosis-infected patient.