bluuebunny/crossref_metadata_2025_split huggingface dataset:
Serological features of antibodies to protamine inducing thrombocytopenia and thrombosis
Authors: Panzer Simon , Schiferer Arno , Steinlechner Barbara , Drouet Ludovic , Amiral Jean 
Published: August 2014

AbstractA significant proportion of patients undergoing cardiopulmonary bypass develop anti-protamine antibodies, with or without the association of thromboembolic events.We extensively investigated the serological features of protamine antibodies, which developed in six patients who were clinically suspected to have heparin-induced thrombocytopenia (HIT). Three patients had thrombotic events. Sera were tested by four different commercially available immunoassays, a heparin-platelet aggregation test, and for their binding properties to heparin, platelet factor 4 (PF4), complex heparin-PF4, protamine, and protamine complex with heparin. Sera from four patients were also tested for the capability to induce platelet activation and the formation of platelet-monocyte heterotypic aggregates.The ELISA assay Zymutest HIA was strongly positive in all cases, the HPIA Asserachrome was borderline, and the gel centrifugation test PaDGIA was positive in two tested patients. Platelet aggregation tests were negative. Using a variation of the Zymutest HIA we demonstrate that IgG antibodies bound only to protamine or protamine complex with heparin, but not to heparin or PF4 only. Sera-induced platelet P-selectin expression and the formation of platelet-monocyte aggregates. Blood samples from one patient proofed positive concomitantly with the thromboembolic event. However, serological characteristics did not differ between antibodies associated with thromboembolic events from those without.These data show that protamine-induced antibodies are specific and may induce platelet activation, which explains their association with thromboembolic events.
Characterization of the Robin function by extremal problems
Authors: Dittmar Bodo 
Published: August 2014

Abstract
In [`Robin function and conformal welding – A new proof of the existence', submitted] a new proof of the existence of the Robin function is given using conformal welding. This proof is essentially based on the simply connected case and a conformal mapping which maps the domain onto a complement of a disk and a system of radial spires.
The aim of this note is to show that this proof also has a wider meaning, namely that this mapping is the unique solution of extremal problems, which minimizes the length or the diameter of a subset of the boundary curve. As a consequence we obtain sharp inequalities for the Robin capacity and the logarithmic capacity.
Analysis of cold temperature effect on stress wave velocity in green wood
Authors: Xu Huadong , Wang Lihai 
Published: August 2014

Abstract
The objective of this study was to investigate the effect of temperature on stress wave velocity (SWV) in green wood below zero degress centigrade (0°C). Both field and laboratory tests were conducted on standing Korean pine trees and small wood samples to study the effects of low temperature at various moisture content (MC) on SWV. As expected, SWV in wood increased with decreasing temperature. However, near 0°C, the SWV increment was not linear but showed disproportional high increments at MCs above 50%. To explain this phenomenon, differential scanning calorimeter (DSC) measurements were performed at various MCs and temperatures, i.e., the interrelation between the state of water aggregation and SWV was analyzed. The explanation of the irregular behavior of SWV as a function of temperature is straightforward: free water and a small portion of bound water in green wood are transformed from water to ice below zero degrees (0°C) centigrade. Thus the disproportional high SWV increment below 0°C reflects the aggregation change of water because the SWV in ice is higher than that in liquid water.
Development of monoclonal antibodies to human kallikrein-related peptidase 6 (KLK6) and their use in an immunofluorometric assay for free KLK6
Authors: Ott Catherine , Ainciburu Mireille , Parent Christelle , Michel Sandrine , Roesch Céline , Vourc’h Patrick , Corcia Philippe , Heuze-Vourc’h Nathalie , Jolivet-Reynaud Colette , Courty Yves 
Published: August 2014

Abstract
We have raised monoclonal antibodies against KLK6 and constructed a ‘sandwich’ type immunoassay using 8A8G3 as capture and 3H3E9 as tracer antibodies. 8A8G3 bound to one side of KLK6, whereas 3H3E9 probably bound near its catalytic site. The assay did not detect complexed forms of KLK6, indicating that it quantifies only free KLK6 (fKLK6). fKLK6 was higher in serum of patients with ovarian cancer (11.34 μg/l±1.37) than in controls (3.39 μg/l±0.42). The cerebrospinal fluid contained high concentrations of fKLK6 (257–965 μg/l). This assay could facilitate the evaluation of fKLK6 in human diseases.
Prognostic significance of human tissue kallikrein-related peptidases 6 and 10 in gastric cancer
Authors: Kolin David L. , Sy Keiyan , Rotondo Fabio , Bassily Mena N. , Kovacs Kalman , Brezden-Masley Christine , Streutker Catherine J. , Yousef George M. 
Published: August 2014

Abstract
The prognosis of patients following surgery for gastric cancer is often poor and is estimated using traditional clinicopathological parameters, which can be inaccurate predictors of future survival. Kallikreins are a group of serine proteases, which are differentially expressed in many human tumors and are being investigated as potential cancer biomarkers. This study assessed the prognostic utility of human tissue kallikrein-like peptidases 6 and 10 (KLK6 and KLK10) and correlated their expression with histopathological and clinical parameters in gastric cancer. We constructed a gastric tumor tissue microarray from 113 gastrectomy specimens and quantified KLK6 and KLK10 expression using immunohistochemistry. To overcome the problem of inter-observer variability and subjectivity in immunohistochemistry interpretation, a whole-slide scanned image of the tissue microarray was analyzed using an automated algorithm to quantify staining intensity. KLK6 expression was positively correlated with nodal involvement (p=0.002) and was predictive of advanced-stage disease (p<0.05). Kaplan-Meier survival curves revealed that tumors expressing high levels of KLK6 were significantly associated with significantly lower overall survival (p=0.04). KLK10 overexpression was also a predictor of advanced-stage disease (p<0.01), but was not significantly correlated with lymph node involvement or survival period. Our results show the potential ability of KLK6 as a prognostic marker for gastric cancer.
p-divisibility of conjugacy class sizes and normal p-complements
Authors: Beltrán Antonio , Felipe María José , Shao Changguo 
Published: August 2014

Abstract
Let N be a normal subgroup of a group G and let p be a prime. We prove that if the p-part of |x|
G
is a constant for every prime-power order element x ∈ N∖Z(N), then N is solvable and has normal p-complement.
Approximately Unbiased Estimator for Non-Normal Process Capability Index CNpk
Authors: Pearn W. L. , Tai Y. T. , Hsiao I. F. , Ao Y. P. 
Published: August 2014

Abstract
Process capability indices (PCIs) have been extensively used to evaluate and measure whether the process meets the specifications and they provide quality assurance and guide a principal for quality improvement. The index Cpk is the most popular index and is widely used in the manufacturing industry for manufacturing yield evaluation. However, typical evaluations of Cpk depend heavily on the assumption of normal variability. When the underlying distributions are non-normal, the capability evaluations are highly unreliable. In the paper, we apply four various bootstrap methods to construct lower confidence bounds of CNpk for non-normal processes. We also propose an approximately unbiased estimator of CNpk for the non-normal processes. Comparisons among the four bootstrap methods with different estimators are provided.
Epigenetic memory in plants
Authors: Iwasaki Mayumi , Paszkowski Jerzy 
Published: August 2014

AbstractEpigenetics refers to heritable changes in patterns of gene expression that occur without alterations in DNA sequence. The epigenetic mechanisms involve covalent modifications of DNA and histones, which affect transcriptional activity of chromatin. Since chromatin states can be propagated through mitotic and meiotic divisions, epigenetic mechanisms are thought to provide heritable ‘cellular memory’. Here, we review selected examples of epigenetic memory in plants and briefly discuss underlying mechanisms.
Editorial
Authors: Leite José Yvan Pereira 
Published: August 2014

A tecnologia mineral como campo de pesquisa apresenta contribuições acadêmicas e industriais, demonstrando sua vitalidade e interação com o setor produtivo e os centros de pesquisa. É, justamente, essa área a ser contemplada neste terceiro volume da HOLOS, que apresenta artigos recomendados pelo XXV Encontro Nacional de Tratamento de Minérios e Metalurgia Extrativa e VIII Meeting of the Southern Hemisphere on Mineral Technology, realizado em outubro de 2013, em Goiânia/GO.Assim, nesta edição especial, são publicados 44 artigos, abordando as seguintes temáticas:Caracterização tecnológica;Cominuição e classificação;Concentração mineral com ênfase na flotação;Espessamento;Processos hidrometalúrgicos;Tratamento de efluentes;Reciclagem;Simulação.As contribuições são majoritariamente do Brasil, no entanto entre elas estão duas da Turquia e uma da Colômbia. Esse grande quantitativo de artigos na área de tecnologia mineral deverá estimular uma maior periodicidade de contribuições dessa área, fazendo este periódico despontar como um dos interlocutores para a manutenção das discussões acadêmicas e tecnológicas nessa área.Dando continuidade à política institucional de difusão científica, este volume já conta com o Digital Object Identifier (DOI) em todos os seus artigos, garantindo sua indexação na plataforma CrossRef - http://www.crossref.org/. No caso deste periódico, os DOI’s aparecem com o formato – DOI: http://dx.doi.org/10.15628/holos.2014.1841. Nem é preciso dizer que ações dessa natureza ajudam a consolidar o periódico, levando-o também a pleitear o acesso a novos indexadores.Também nesta edição passam a compor o conselho editorial os pesquisadores José Luis Silva Netto Junior (Economia, UFPB) e Nelma Mirian Chagas de Araújo (Eng. de Produção, IFPB). E, ao longo do ano, outros pesquisadores devem se integrar a esse conselho, visando fortalecer a representação multidisciplinar que caracteriza este periódico.Neste ano de comemorações do Ano 30 e dos 10 Anos online de HOLOS, observamos, assim, a excelente trajetória da contribuição do Instituto Federal do Rio Grande do Norte para a difusão científica. O êxito de um veículo Open Acess como a HOLOS, cuja qualidade e perenidade têm-se mantido em todo esse tempo, deve-se a valiosa colaboração dos autores, dos avaliadores e do conselho editorial, que vêm sustentando o desenvolvimento deste periódico.Em face dessa realidade, convido-os a compartilhar a alegria das comemorações com a leitura dos artigos aqui apresentados. Prof. José Yvan Pereira Leite
Motives for Going International and Entry Modes of Family Firms in Poland
Authors: Daszkiewicz Nelly , Wach Krzysztof 
Published: August 2014

Abstract
Currently, the internationalisation of family businesses (FBs) is an increasingly important research area. Substantial numbers of FBs are forced to expand into foreign markets in order to survive and grow in the competitive environment. However various research findings show that internationalisation of FBs may proceed differently than in the case of firms with different ownership structure. The article is both theoretical and empirical. In the theoretical part it focuses on theoretical concepts of firm internationalisation and specifics of internationalisation of FBs, especially their motives for going international. In the empirical part the quantitative approach was adopted. The results of the survey are presented on the sample of 216 firms, including 88 FBs (were investigated with the use of a survey questionnaire). Then, the statistical analysis is carried out.
Coopetition as a Chance of Increasing The Level of Investments Made by Family Companies in Poland
Authors: Ejsmont Aneta 
Published: August 2014

Abstract
The main problem described by the authoress of the present article is increased investment risk of family companies in Poland by worse economic situation in our country. Authoress’ planned aim of the present study is to demonstrate the joint-stock companies listed on the New Connect market who as potential investors must be aware of the risk connected with investing in financial instruments in The Alternative System of Turnover and their investment decisions should be preceded by proper analysis and, if situation requires it, consultation with an investment adviser, what for many micro, small and middle family firms is unfortunately simply too expensive. The condition to increase the level of investments in the researched family companies in Poland is coopetition of that companies with big holding companies or concerns from Poland and with economic entities from other EU countries. In order to do so was made an analysis of the researched enterprises which are joint-stock companies listed on the New Connect market with regard to the level of investments which can influence intensity of cooperation and competition of family firms in Poland with other economic entities
Intercultural dimensions of entrepreneurship
Authors: Radziszewska Aleksandra 
Published: August 2014

Abstract
Entrepreneurship is increasingly being recognized as an important factor for economic growth and the regeneration of economies. The importance of different cultural dimensions and their effect on entrepreneurship has been noted in a number of studies. This paper focuses on national culture as a determinant of entrepreneurship, and family firms’ creation. National culture is important for interpreting for the differences of entrepreneurial activities across countries. The different dimensions of national culture affect different aspects of entrepreneurship and opportunities family firms’ creation. The paper describes the effect of national culture on entrepreneurship in different cultural communities using the Hofstede’s model and GLOBE study.
Viticulture in The Czech Republic: Some Spatio-Temporal Trends
Authors: Svobodová Ilona , Věžník Antonín , Král Michael 
Published: August 2014

Abstract
From a global perspective, the growing of grapevines in the Czech Republic is of peripheral importance. For a group of grape-growing villages in southern Moravia, however, the making of wine is bound up with local history, traditions and cultural life, and contributes significantly to the local economy. This paper describes the current status of viticulture in Bohemia and Moravia, addressing changes in the number and structure of wine producers and pointing out some qualitative changes that the business is undergoing. Changing consumer tastes have brought a demand for quality wines of local origin, which cannot be met without high quality care of vineyards throughout the lifetime of the vines. Special attention is given to two alternative ways of tending vineyards - the development of integrated production, and organic viticulture - that are developing rapidly in the Czech Republic even when compared to Austria and Germany
Coordination of and Through E-Government: The Case of the Czech Republic
Authors: Špaček David 
Published: August 2014

Abstract
Although e-government as a research topic is rather embedded in public-administration literature, and coordination of and through e-government is visible in European countries, coordination of and through e-government has not been paid much attention. Consequently this paper deals with this topic. Its text outlines emerging coordination practices that can be observed in European countries, and it also indicates issues using the Czech e-government development and some key national initiatives as examples. Th e presented text concludes that although elements of strategic planning may become embedded and institutional and regulatory mechanisms stabilized in the country, other issues such as a weak accountability culture may exist and hinder coordination practices.
A Numerical Model to Simulate the Motion of a Lifesaving Module During its Launching from the Ship’S Stern Ramp
Authors: Dymarski Paweł , Dymarski Czesław 
Published: August 2014

Abstract
The article presents a numerical model of object motion in six degrees of freedom (DoF) which is intended to be used to simulate 3D motion of a lifesaving module during its launching from a ship using a stern ramp in rough sea. The model, of relatively high complexity, takes into account both the motion of the ship on water in changing sea conditions, and the relative motion of the ramp with respect to the ship.
The motion of the ramp changes and strongly depends on its constructional and geometrical parameters. The presented model takes into account the displacement of the submerged part of the ramp, as well as its damping in the water and the interaction with the module moving on it. The results of test simulation of a module launching from the ship in still water are included.
The Quick Measure of a Nurbs Surface Curvature for Accurate Triangular Meshing
Authors: Kniat Aleksander 
Published: August 2014

Abstract
NURBS surfaces are the most widely used surfaces for three-dimensional models in CAD/ CAE programs. When a model for FEM calculation is prepared with a CAD program it is inevitable to mesh it finally. There are many algorithms for meshing planar regions. Some of them may be used for meshing surfaces but it is necessary to take the curvature of the surface under consideration to avoid poor quality mesh. The mesh must be denser in the curved regions of the surface. In this paper, instead of analysing a surface curvature, the method to assess how close is a mesh triangle to the surface to which its vertices belong, is presented. The distance between a mesh triangle and a parallel tangent plane through a point on a surface is the measure of the triangle quality. Finding the surface point whose projection is located inside the mesh triangle and which is the tangency point to the plane parallel to this triangle is an optimization problem. Mathematical description of the problem and the algorithm to find its solution are also presented in the paper.
Flow of Liquid in Flat Gaps of the Satellite Motor Working Mechanism
Authors: Sliwiński Paweł 
Published: August 2014

Abstract
The article describes the methodology and results of investigations of the flow of oil and HFA-E emulsion in flat gaps of the working mechanism of a satellite motor. The flow of liquid in those gaps is turbulent and not fully developed. The article presents two methods of modelling this flow. Method I makes use of the Darcy-Weisbach formula, while Method II bases on the assumption that in the variable-length gaps the flow is turbulent in the area where the length is the smallest and laminar where the length is the largest. Consequently, the flow in such gaps can be modelled as the sum of laminar and turbulent flows. The results obtained in the experiment have made the basis for calculating relevant coefficients and assessing the proportion of turbulence in the flow modelled using both methods
Bead-On-Plate Welding on S235JR Steel by Underwater Local Dry Chamber Process
Authors: Rogalski Grzegorz , Łabanowski Jerzy , Fydrych Dariusz , Tomków Jacek 
Published: August 2014

Abstract
The article presents the results of the effect of parameters of underwater local dry chamber welding on the properties of padding welds. The effect of heat input and the type of shielding gas on the structure and hardness of welds was established. the functions for estimating the maximum hardness of the heat affected zone have been also elaborated
Two New Species of The Genus Eurycope (Isopoda, Munnopsidae) from Icelandic Waters
Authors: Schnurr Sarah , Malyutina Marina V 
Published: August 2014

AbstractCollections of munnopsid isopods of the BIOICE (Benthic Invertebrates of Icelandic Waters; 1991–2004) and the IceAGE1 (Icelandic Marine Animals: Genetics and Ecology; since 2011) expeditions included ten species of the genusEurycopeG.O. Sars, 1864, thereof are two species new to science. Thus, the descriptions of the two new species are presented herein.Eurycope elianaesp. n. is distinguished from the other species of the genus mainly by two long, slightly robust, simple setae on the tip of the rostrum in combination with the size and shape of the rostrum itself.E elianaesp. n. shares the presence of two long, slightly robust, simple seta on the tip of the rostrum withE. tumidicarpus. The shape of the rostrum itself is more similar toE. inermisand species of theE. complanatacomplex.E. aculeatasp. n. is characterized by possessing dorsomedial acute projections on pereo-nites 5–7, which is unusual for the genus.E. aculeatasp. n. is most similar toE. cornuta. Both new species are, so far, known only from localities south of the Greenland-Scotland Ridge.
Phylogeographic Estimates of Colonization of The Deep Atlantic by The Protobranch Bivalve Nucula Atacellana
Authors: Jennings Robert M. , Etter Ron J. 
Published: August 2014

AbstractThe Pleistocene and post-Pleistocene evolutionary history of many North Atlantic intertidal invertebrate species is well known, but the evolutionary history of the deep North Atlantic fauna is poorly understood, specifically whether colonization of the deep North Atlantic paralleled the patterns observed in shallow water. Contemporary pan-Atlantic species distributions could result from several colonization pathways that connected different regions of the Atlantic at different times (e.g. Arctic, Antarctic or Panamanian pathways). To test potential colonization pathways we quantified geographic variation in nuclear and mitochondrial markers from Atlantic samples ofNucula atacellana, a pan-Atlantic deep-sea protobranch bivalve, usingN. profundorumin the eastern central Pacific as an outgroup. We combined existing 16S data from North and South Atlantic populations ofN. atacellanawith new sequences of 16S, COI, and an intron of calmodulin from those populations, and newly sampled populations near Iceland. Population genetic analyses indicated a subtropical expansion via the Central American Seaway. We found no evidence for Transarctic migration to the Atlantic inN. atacellana, which suggests that colonization pathways may differ significantly between shallow- and deep-water fauna.