bluuebunny/crossref_metadata_2025_split huggingface dataset:
HOUSES OF STYLE: CONSUMPTION, ADORNMENT, AND IDENTITY IN FORMATIVE TLAXCALAN HOUSEHOLDS
Authors: Carballo David M. , Carballo Jennifer , Lesure Richard G. 
Published: January 2015

AbstractThe households of Formative period central Mexico represent critical loci for understanding major social transformations during a millennium (900b.c.–a.d.100) that witnessed the expansion and contraction of several macro-regional stylistic and economic networks, formalization of enduring political and religious institutions, and initial urbanization and state formation. Households and their constituent members used style to articulate important elements of their identity through practices of group consumption and personal adornment. In this study we consider style within the context of ceramic serving vessels and portable adornments primarily from sites in the state of Tlaxcala. We evaluate the manner in which dimensions of stylistic expression in these material goods contributed to shifting conceptualizations of household and individual identity and their articulation with community and supra-community social networks, noting the generally collective or affinitive manipulation of styles with means of socially differentiating age, status, and other dimensions of identity.
AREAL SHIFTS IN CLASSIC MAYAN PHONOLOGY
Authors: Law Danny , Robertson John , Houston Stephen , Zender Marc , Stuart David 
Published: January 2015

AbstractAdvances in hieroglyphic decipherment and in language contact typology provide new data and theories with which to investigate and reassess prior interpretations of Mayan linguistic history. The present study considers the shift from proto-Mayan*kand *k'to /ch/ and /ch'/, a sound change that affected several Mayan languages in different phonological contexts. This sound change, with a very particular set of conditions, has been highlighted as a defining feature of the Cholan-Tseltalan branch of the Mayan language family. New evidence suggests that this sound change was shared as a result of contact around the time of the Classic period, rather than reflecting an inherited sound change that would have taken place at a much earlier stage of the language family. Hieroglyphic data provide further evidence that this sound change was adopted in the hieroglyphic language in a word-by-word fashion, rather than applying to all similar phonological contexts at the same time.
EVERYDAY ACTION AND THE RISE AND DECLINE OF ANCIENT POLITIES: HOUSEHOLD STRATEGY AND POLITICAL CHANGE IN POSTCLASSIC XALTOCAN, MEXICO
Authors: De Lucia Kristin , Overholtzer Lisa 
Published: January 2015

AbstractHousehold archaeology conducted at the site of Xaltocan, an important regional center in the northern Basin of Mexico, illustrates how the everyday actions of ordinary people contribute to the rise and decline of ancient polities. Through a study of long-term change and variation from multiple household contexts, this article reconstructs how the economic and political activities of ordinary households were central to the construction and reproduction of political institutions, social structures, and regional systems of exchange from the period of Xaltocan's founding arounda.d.900 through its conquest ina.d.1395. Along with the other contributors to this volume we emphasize that households are not simply influenced by broader processes of change and development in a trickle-down fashion, but rather that micro- and macro-structures are mutually constituted, with household decisions and actions having both intended and unintended consequences at the macroscale.
Secondary dormancy inBrassica napusis correlated with enhancedBnaDOG1transcript levels
Authors: Née Guillaume , Obeng-Hinneh Evelyn , Sarvari Pourya , Nakabayashi Kazumi , Soppe Wim J.J. 
Published: January 2015

AbstractDormancy has evolved in plants to restrict germination to favourable growth seasons. Seeds from most crop plants have low dormancy levels due to selection for immediate germination during domestication. Seed dormancy is usually not completely lost and low levels are required to maintain sufficient seed quality.Brassica napuscultivars show low levels of primary seed dormancy. However,B. napusseeds are prone to the induction of secondary dormancy, which can lead to the occurrence of volunteers in the field in subsequent years after cultivation. TheDELAY OF GERMINATION 1(DOG1) gene has been identified as a major dormancy gene in the model plantArabidopsis thaliana.DOG1is a conserved gene and has been shown to be required for seed dormancy in various monocot and dicot plant species. We have identified threeB. napusgenes with high homology toAtDOG1, which we namedBnaA.DOG1.a,BnaC.DOG1.aandBnaC.DOG1.b. The transcripts of these genes could only be detected in seeds and showed a similar expression pattern during seed maturation asAtDOG1. In addition, theBnaDOG1genes showed enhanced transcript levels after the induction of secondary dormancy. These results suggest a role forDOG1in the induction of secondary dormancy inB. napus.
The potential impact of animal protein intake on global and abdominal obesity: evidence from the Observation of Cardiovascular Risk Factors in Luxembourg (ORISCAV-LUX) study
Authors: Alkerwi Ala’a , Sauvageot Nicolas , Buckley Jonathan D , Donneau Anne-Françoise , Albert Adelin , Guillaume Michèle , Crichton Georgina E 
Published: January 2015

AbstractObjectiveTo examine the association of total animal protein intake and protein derived from different dietary sources (meat; fish and shellfish; eggs; milk products) with global and abdominal obesity among adults in Luxembourg.DesignBinary logistic regression analysis was used to assess the relationship between animal protein intake (as a percentage of total energy intake) and global obesity (BMI≥30·0 kg/m2) and abdominal obesity (waist circumference ≥102 cm for men and ≥88 cm for women), after controlling for potential confounders.SettingObservation of Cardiovascular Risk Factors in Luxembourg (ORISCAV-LUX) study.SubjectsThe study population was derived from a national cross-sectional stratified sample of 1152 individuals aged 18–69 years, recruited between November 2007 and January 2009.ResultsThere was an independent positive association between total animal protein intake and both global (OR=1·18; 95 % CI 1·12, 1·25) and abdominal obesity (OR=1·14; 95 % CI 1·08, 1·20) after adjustment for age, gender, education, smoking, physical activity and intakes of total fat, carbohydrate, fibre, and fruit and vegetables. Protein intakes from meat, fish and shellfish were positively associated with global and abdominal obesity with further adjustment for vegetal protein and other sources of animal-derived protein (all P<0·01). Protein derived from eggs or milk products was unrelated to global or abdominal obesity.ConclusionsOur findings suggest that protein derived from animal sources, in particular from meat, fish and shellfish, may be associated with increased risk of both global and abdominal obesity among presumably healthy adults in Luxembourg. These findings suggest that lower animal protein intakes may be important for maintenance of healthy body weight.
The conserved Trp114 residue of thioredoxin reductase 1 has a redox sensor-like function triggering oligomerization and crosslinking upon oxidative stress related to cell death
Authors: Xu J , Eriksson S E , Cebula M , Sandalova T , Hedström E , Pader I , Cheng Q , Myers C R , Antholine W E , Nagy P , Hellman U , Selivanova G , Lindqvist Y , Arnér E S J 
Published: January 2015

AbstractThe selenoprotein thioredoxin reductase 1 (TrxR1) has several key roles in cellular redox systems and reductive pathways. Here we discovered that an evolutionarily conserved and surface-exposed tryptophan residue of the enzyme (Trp114) is excessively reactive to oxidation and exerts regulatory functions. The results indicate that it serves as an electron relay communicating with the FAD moiety of the enzyme, and, when oxidized, it facilitates oligomerization of TrxR1 into tetramers and higher multimers of dimers. A covalent link can also be formed between two oxidized Trp114 residues of two subunits from two separate TrxR1 dimers, as found both in cell extracts and in a crystal structure of tetrameric TrxR1. Formation of covalently linked TrxR1 subunits became exaggerated in cells on treatment with the pro-oxidant p53-reactivating anticancer compound RITA, in direct correlation with triggering of a cell death that could be prevented by antioxidant treatment. These results collectively suggest that Trp114 of TrxR1 serves a function reminiscent of an irreversible sensor for excessive oxidation, thereby presenting a previously unrecognized level of regulation of TrxR1 function in relation to cellular redox state and cell death induction.
The BH3-only protein Bad is dispensable for TNF-mediated cell death
Authors: Ottina E , Sochalska M , Sgonc R , Villunger A 
Published: January 2015

AbstractTumor necrosis factor (TNF) is a key signaling molecule orchestrating immune and inflammatory responses and possesses the capacity to trigger apoptotic as well as necroptotic cell death. Apoptotic cell death elicited by TNF has been demonstrated to engage pro-apoptotic Bcl-2 family proteins, most prominently the BH3-only protein Bid, a key substrate of caspase-8, the key effector protease downstream of TNF receptor I. Most recently, the BH3 domain-containing protein Bad (Bcl-2-antagonist of cell death) has been shown to be rate limiting for TNF-mediated cell death, suggesting possible synergy with Bid, but genetic analyses presented here demonstrate that it is dispensable for this process.
Whole-exome sequencing reveals the mutational spectrum of testicular germ cell tumours
Authors: Litchfield Kevin , Summersgill Brenda , Yost Shawn , Sultana Razvan , Labreche Karim , Dudakia Darshna , Renwick Anthony , Seal Sheila , Al-Saadi Reem , Broderick Peter , Turner Nicholas C. , Houlston Richard S. , Huddart Robert , Shipley Janet , Turnbull Clare 
Published: January 2015

AbstractTesticular germ cell tumours (TGCTs) are the most common cancer in young men. Here we perform whole-exome sequencing (WES) of 42 TGCTs to comprehensively study the cancer's mutational profile. The mutation rate is uniformly low in all of the tumours (mean 0.5 mutations per Mb) as compared with common cancers, consistent with the embryological origin of TGCT. In addition to expected copy number gain of chromosome 12p and mutation of KIT, we identify recurrent mutations in the tumour suppressor gene CDC27 (11.9%). Copy number analysis reveals recurring amplification of the spermatocyte development gene FSIP2 (15.3%) and a 0.4 Mb region at Xq28 (15.3%). Two treatment-refractory patients are shown to harbour XRCC2 mutations, a gene strongly implicated in defining cisplatin resistance. Our findings provide further insights into genes involved in the development and progression of TGCT.
Mutual information reveals multiple structural relaxation mechanisms in a model glass former
Authors: Dunleavy Andrew J. , Wiesner Karoline , Yamamoto Ryoichi , Royall C. Patrick 
Published: January 2015

AbstractAmong the key challenges to our understanding of solidification in the glass transition is that it is accompanied by little apparent change in structure. Recently, geometric motifs have been identified in glassy liquids, but a causal link between these motifs and solidification remains elusive. One ‘smoking gun’ for such a link would be identical scaling of structural and dynamic lengthscales on approaching the glass transition, but this is highly controversial. Here we introduce an information theoretic approach to determine correlations in displacement for particle relaxation encoded in the initial configuration of a glass-forming liquid. We uncover two populations of particles, one inclined to relax quickly, the other slowly. Each population is correlated with local density and geometric motifs. Our analysis further reveals a dynamic lengthscale similar to that associated with structural properties, which may resolve the discrepancy between structural and dynamic lengthscales.
Determination of the quantized topological magneto-electric effect in topological insulators from Rayleigh scattering
Authors: Ge Lixin , Zhan Tianrong , Han Dezhuan , Liu Xiaohan , Zi Jian 
Published: January 2015

AbstractTopological insulators (TIs) exhibit many exotic properties. In particular, a topological magneto-electric (TME) effect, quantized in units of the fine structure constant, exists in TIs. Here, we theoretically study the scattering properties of electromagnetic waves by TI circular cylinders particularly in the Rayleigh scattering limit. Compared with ordinary dielectric cylinders, the scattering by TI cylinders shows many unusual features due to the TME effect. Two proposals are suggested to determine the TME effect of TIs simply by measuring the electric-field components of scattered waves in the far field at one or two scattering angles. Our results could also offer a way to measure the fine structure constant.
PACT/RAX Regulates the Migration of Cerebellar Granule Neurons in the Developing Cerebellum
Authors: Yong Yue , Meng Ya , Ding Hanqing , Fan Zhiqin , Tang Yifen , Zhou Chenghua , Luo Jia , Ke Zun-Ji 
Published: January 2015

AbstractPACT and its murine ortholog RAX were originally identified as a protein activator for the dsRNA-dependent, interferon-inducible protein kinase PKR. Recent studies indicated that RAX played a role in embryogenesis and neuronal development. In this study, we investigated the expression of RAX during the postnatal development of the mouse cerebellum and its role in the migration of cerebellar granule neurons (CGNs). High expression of RAX was observed in the cerebellum from postnatal day (PD) 4 to PD9, a period when the CGNs migrate from the external granule layer (EGL) to the internal granule layer (IGL). The migration of the EGL progenitor cells in vivo was inhibited by RAX knockdown on PD4. This finding was confirmed by in vitro studies showing that RAX knockdown impaired the migration of CGNs in cerebellar microexplants. PACT/RAX-regulated migration required its third motif and was independent of PKR. PACT/RAX interacted with focal adhesion kinase (FAK) and PACT/RAX knockdown disturbed the FAK phosphorylation in CGNs. These findings demonstrated a novel function of PACT/RAX in the regulation of neuronal migration.
All Cues Are Not Created Equal: The Case for Facilitating the Acquisition of Typical Weighting Strategies in Children With Hearing Loss
Authors: Lowenstein Joanna H. , Nittrouer Susan 
Published: January 2015

Purpose
One task of childhood involves learning to optimally weight acoustic cues in the speech signal in order to recover phonemic categories. This study examined the extent to which spectral degradation, as associated with cochlear implants, might interfere. The 3 goals were to measure, for adults and children, (a) cue weighting with spectrally degraded signals, (b) sensitivity to degraded cues, and (c) word recognition for degraded signals.

Method
Twenty-three adults and 36 children (10 and 8 years old) labeled spectrally degraded stimuli from /bɑ/-to-/wɑ/ continua varying in formant and amplitude rise time (FRT and ART). They also discriminated degraded stimuli from FRT and ART continua, and recognized words.

Results
A developmental increase in the weight assigned to FRT in labeling was clearly observed, with a slight decrease in weight assigned to ART. Sensitivity to these degraded cues measured by the discrimination task could not explain variability in cue weighting. FRT cue weighting explained significant variability in word recognition; ART cue weighting did not.

Conclusion
Spectral degradation affects children more than adults, but that degradation cannot explain the greater diminishment in children's weighting of FRT. It is suggested that auditory training could strengthen the weighting of spectral cues for implant recipients.
Predicting Vocabulary Growth in Children With and Without Specific Language Impairment: A Longitudinal Study From 2;6 to 21 Years of Age
Authors: Rice Mabel L. , Hoffman Lesa 
Published: January 2015

Purpose
Children with specific language impairment (SLI) often have vocabulary impairments. This study evaluates longitudinal growth in a latent trait of receptive vocabulary in affected and unaffected children ages 2;6 (years;months) to 21 years and evaluates as possible predictors maternal education, child gender, and nonverbal IQ.

Method
A sample of 519 participants (240 with SLI; 279 unaffected) received an average of 7 annual assessments for a total of 3,012 latent trait Peabody Picture Vocabulary Test (PPVT) observations. Unconditional and conditional multilevel growth models were estimated to evaluate growth trajectories and predictor relationships over time.

Results
Children with SLI had lower levels of receptive vocabulary throughout the age range assessed. They did not close the gap with age peers. Children with higher nonverbal IQs had better PPVT performance, as did children of mothers with higher education. Child gender showed an advantage for young girls that leveled out with age and then became an advantage for boys from ages 10 to 21 years. All children's rate of vocabulary acquisition slowed around 12 years of age.

Conclusions
The outcomes of the study have implications for hypothesized causal pathways for individual differences; predictions differ for children under 5 years, 6–10 years, and later ages.
Clostridium-difficile-Infektionen – Ein zunehmendes Problem in deutschen Krankenhäusern
Authors: Dormann Arno , Weinke Thomas 
Published: January 2015

ZusammenfassungDie Inzidenz durch Clostridium difficile ausgelöster Enterokolitiden (C.-difficile-Infektionen, CDI) hat in den letzten Jahren in deutschen Krankenhäusern deutlich zugenommen. Abhängig von verschiedenen Risikofaktoren kann die Infektion sehr schwer oder sogar lebensbedrohlich verlaufen. Tritt also eine nosokomiale Diarrhö auf, sollte daher immer an eine Infektion mit Clostridium difficile gedacht und die Diagnostik und gegebenenfalls eine angemessene Therapie zeitnah eingeleitet werden. Eine besondere Herausforderung sind die mit einer C.-difficile-Infektion einhergehenden hohen Rückfallraten. Dabei unterscheiden sich die bei schweren Verläufen oder erhöhtem Rückfallrisiko empfohlenen Antibiotika Vancomycin und Fidaxomicin hinsichtlich der Wahrscheinlichkeit eines Rückfalls. Einer der Hauptrisikofaktoren für eine CDI ist der Einsatz von Breitspektrumantibiotika, weshalb ihr sorgsamer und differenzierter Einsatz empfohlen wird, um Clostridium-difficile-Infektionen möglichst einzudämmen. Hygienemaßnahmen wie das gründliche Waschen der Hände mit Wasser und Seife tragen dazu bei, die Verbreitung der C.-difficile-Sporen zu verhindern.
Socio‐economic status and motor performance of children and adolescents
Authors: Klein Markus , Fröhlich Michael , Pieter Andrea , Emrich Eike 
Published: January 2015

AbstractThe study examines the question to what extent children and adolescents differ in terms of motor performance in dependence of their socio‐economic status (SES). A sample of 1389 students in Saarland (Germany) in various grades (1st grade: age 7.26 ± 0.38 years, 4th grade: 10.3 ± 0.4 years, 7th grade: 13.44 ± 0.49 years, 10th grade: 16.36 ± 0.69 years) has been examined. Their motor performance has been measured by means of 20‐m sprint, standing long jump and a 6‐minute run, and the SES by means of a parent survey. Based on the indicators school education, professional education, job position and household income, the SES was categorised in a three‐step approach (low, middle, high). The influence on dependent variables was analysed by using multivariate analysis of variance. Students with a higher SES exhibit a higher motor performance compared with that of lower SES (results of the multivariate: Pillai's Trace =. 05, F[6; 2526] = 12.56, p =. 001; = 0.03). In addition, the data for students of higher SES differ significantly from the data of a German reference sample (higher motor performance compared with standard values). In contrast, persons of lower SES do not differ from the reference sample, and those of middle SES differ only slightly from the reference sample. The results are relevant when considering specific prevention efforts concerning motor performance of certain groups. Especially those institutions and schools should be focused upon whose catchment area includes a high share of socially disadvantaged population groups.
Rubens’sLife of Maria de’ Medici:Dissimulation and the Politics of Art in Early Seventeenth-Century France*
Authors: Galletti Sara 
Published: January 2015

AbstractTheLife of Maria de’ Medici,the biographical series of twenty-four large-size paintings executed for the Queen Mother of France by Peter Paul Rubens in 1622–25, is traditionally regarded by historians as both a masterpiece of Baroque art and a monument of political naïveté. According to this view, the series was a disrespectful visual bravado that exposed both patron and painter to scandal by publicly advertising the queen’s political ideas and ambitions, which were not only audacious, but often in opposition to those of her son King Louis XIII. This article challenges this assessment by reading theLifewithin the context of seventeenth-century uses of dissimulation and spatial control as strategies to limit both intellectual and physical access to information. It argues that the series was imbued with multiple layers of meaning, intended for different audiences, and that access to these was strictly controlled by the queen and her circle.
Bidirectional inward migration of particles lagging behind a Poiseuille flow in a rectangular microchannel for 3D particle focusing
Authors: Kim Young Won , Yoo Jung Yul 
Published: January 2015

Abstract
Electrophoretic mobility of particles dispersed in an electrolyte solution induces the particles to lag behind a Poiseuille flow in a rectangular microchannel, which causes bidirectional inward migration of particles to the central axis of the channel. As a result, in the present theoretical and experimental study, three-dimensional (3D) particle focusing is clearly realized in such a manner that the particles are aligned in a single file along the axis of the channel as they are transported downstream. Theoretical prediction on the particle migration time provides an excellent assessment of the experimental results. The method proposed in the present study has potential for development of low-cost rapid manufacturing process of sheathless monolayer microchips for 3D particle focusing.
Energy efficiency standards and innovation
Authors: Morrison Geoff 
Published: January 2015

Abstract
Van Buskirk et al (2014 Environ. Res. Lett.

9
114010) demonstrate that the purchase price, lifecycle cost and
price of improving efficiency (i.e. the incremental price of efficiency gain)
decline at an accelerated rate following the adoption of the first energy
efficiency standards for five consumer products. The authors show these trends
using an experience curve framework (i.e. price/cost versus cumulative
production). While the paper does not draw a causal link between standards and
declining prices, they provide suggestive evidence using markets in the US and
Europe. Below, I discuss the potential implications of the work.