bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prediction of 2 years-survival in patients with stage I and II non-small cell lung cancer utilizing 18F-FDG PET/CT SUV quantifica
Authors: Cistaro Angelina , Quartuccio Natale , Mojtahedi Alireza , Fania Piercarlo , Filosso Pier Luigi , Campenni Alfredo , Ficola Umberto , Baldari Sergio 
Published: April 2013

Abstract
Background. The purpose of the study was to evaluate the correlation between the maximum standardized uptake value (SUVmax), size of primary lung lesion, disease-free survival (DFS) and overall survival (OS) in patients with stage I and II non-small cell lung cancer (NSCLC) in 2 years follow-up.
Patients and methods. Forty-nine patients with stage I-II NSCLC were included in this study. Pre-surgical 2-deoxy- 2-[18F]fluoro-D-glucose positron-emission tomography (18F-FDG PET/CT) study was performed for all patients. The relationship between SUVmax, tumour size and clinical outcome was measured. The cut-off value for SUVmax and tumour size with the best prognostic significance, probability of DFS and the correlation between SUVmax and the response to therapy were calculated.
Results. There was a statistically significant correlation between SUVmax and DFS (p = 0.029). The optimal cut-offs were 9.00 for SUVmax (p = 0.0013) and 30mm for tumour size (p = 0.0028). Patients with SUVmax > 9 and primary lesion size > 30 mm had an expected 2years-DFS of 37.5%, while this rose to 90% if the tumour was <30 mm and/or SUVmax was <9.
Conclusions. In stage I-II, SUVmax and tumour size might be helpful to identify the subgroup of patients with high chance for recurrence.
Renal Vascular Lesions in Patients with Diabetes Mellitus
Authors: Nicodim Mirela-Simona , Aşchie Mariana , Catrinoiu Doina , Hangan Laurenţiu-Tony 
Published: April 2013

Abstract Background and Aims. Patients with diabetes mellitus, especially type 2 diabetes, have often a multifactorial renal impairment. The aim of this study was to correlate renal vascular lesions occurring in patients with diabetes mellitus with clinical and laboratory parameters. Material and method. We performed a retrospective study on a sample of 127 patients with diabetes mellitus, who died in hospital. Data from necropsies were correlated with the clinical and laboratory data collected from the medical records of these patients. Results. Renal vascular lesions were frequently found in patients from the study group. The most common were nephroangiosclerosis lesions, which correlated with age, diabetes duration, systolic blood pressure and mean fasting glucose. Conclusions. Most patients in the study group had multiple cardiovascular risk factors (advanced age, dyslipidemia, hypertension) that explain the high prevalence of renal vascular lesions.
Possible schemes of photoassociation processes in the KLi molecule with newly calculated potential energy curves
Authors: Miądowicz Łukasz , Jasik Patryk , Sienkiewicz Józef 
Published: April 2013

AbstractWe present four promising schemes for photoassociative formation of KLi molecule in its ground electronic state. Analysis is based on newly calculated adiabatic potentials supported by transition dipole moments and Franck-Condon factors.
Fractional sub-equation method for the fractional generalized reaction Duffing model and nonlinear fractional Sharma-Tasso-Olver equation
Authors: Jafari Hossein , Tajadodi Haleh , Baleanu Dumitru , Al-Zahrani Abdulrahim , Alhamed Yahia , Zahid Adnan 
Published: April 2013

Abstract
In this paper the fractional sub-equation method is used to construct exact solutions of the fractional generalized reaction Duffing model and nonlinear fractional Sharma-Tasso-Olver equation.The fractional derivative is described in the Jumarie’s modified Riemann-Liouville sense. Two illustrative examples are given, showing the accuracy and convenience of the method.
Fractional diffusion equation in half-space with Robin boundary condition
Authors: Duan Jun-Sheng , Wang Zhong , Fu Shou-Zhong 
Published: April 2013

AbstractThe initial and boundary value problem for the fractional diffusion equation in half-space with the Robin boundary condition is considered. The solution is comprised of two parts: the contribution of the initial value and the contribution of the boundary value, for which the respective fundamental solutions are given. Finally, the solution formula of the considered problem is obtained.
Vectorial fractional integral inequalities with convexity
Authors: Anastassiou George 
Published: April 2013

Abstract
Here we present vectorial general integral inequalities involving products of multivariate convex and increasing functions applied to vectors of functions. As specific applications we derive a wide range of vectorial fractional inequalities of Hardy type. These involve the left and right: Erdélyi-Kober fractional integrals, mixed Riemann-Liouville fractional multiple integrals. Next we produce multivariate Poincaré type vectorial fractional inequalities involving left fractional radial derivatives of Canavati type, Riemann-Liouville and Caputo types. The exposed inequalities are of L
p type, p ≥ 1, and exponential type.
Robot-Assisted Therapy for Autism Spectrum Disorders with (Partially) Autonomous Control: Challenges and Outlook
Authors: Thill Serge , Pop Cristina A , Belpaeme Tony , Ziemke Tom , Vanderborght Bram 
Published: April 2013

AbstractRobot-assisted therapy (RAT) is an emerging field that has already seen some success and is likely to develop in the future. One particular application area is within therapies for autism spectrum disorders, in which the viability of the approach has been demonstrated.The present paper is a vision paper with the aim of identifying research directions in the near future of RAT. Specifically, we argue that the next step in such therapeutic scenarios is the development of more substantial levels of autonomy which would allow the robot to adapt to the individual needs of children over longer periods of time (while remaining under the ultimate supervision of a therapist). We argue that this requires new advances on the level of robot controllers as well as the ability to infer and classify intentions, goals and emotional states of the robot’s interactants. We show that the state of the art in a number of relevant disciplines is now at the point at which such an endeavour can be approached in earnest.
Pre-analytical errors and patient safety / Preanalitičke greške i bezbednost pacijenata
Authors: Plebani Mario 
Published: April 2013

Summary
Laboratory medicine, as a specialty that had prioritised quality control, has always been at the forefront of error reduction. In the last decades, a dramatic decrease of analytical errors has been experienced, while a relatively high frequency of errors has been documented in the pre-analytical phase. Most pre-analytical errors, which account for up to 70% of all mistakes made in laboratory diagnostics, arise during patient preparation, and sample collection, transportation, preparation for analysis and storage. However, while it has been reported that the pre-analytical phase is error-prone, only recently has it been demonstrated that most of these errors occur in the »pre-pre-analytical phase«, which comprises the initial procedures of the testing process performed outside the laboratory walls by healthcare personnel outside the direct control of the clinical laboratory. Developments in automation and information technologies have played a major role in decreasing some pre-analytical errors and, in particular, the automation of repetitive, errorprone and bio-hazardous pre-analytical processes performed within the laboratory walls has effectively decreased errors in specimen preparation, centrifugation, aliquot preparation, pipetting and sorting. However, more efforts should be made to improve the appropriateness of test request, patient and sample identification procedures and other pre-analytical steps performed outside the laboratory walls.
The role of vitamin D in multisystem sarcoidosis / Uloga vitamina D u sarkoidozi
Authors: Mihailović-Vučinić Violeta , Ignjatović Svetlana , Dudvarski-Ilić Aleksandra , Stjepanović Mihailo , Vuković Mira , Omčikus Maja , Singh Sandra , Popević Spasoje , Videnović-Ivanov Jelica , Filipović Snežana 
Published: April 2013

Summary
Recently published data indicate that vitamin D abnormalities are common in sarcoidosis patients. The purpose of this study was to compare serum vitamin 25(OH)D levels among sarcoidosis patients with different clinical cour - ses of the disease. The study also included the first observations on cognitive functions (i.e. depression and fatigue syndrome) in relation to vitamin D deficiency in sarcoidosis patients. At the Biochemical Laboratory of the Clinical Center of Serbia, Belgrade, vitamin D25(OH)D was measured using the Elecsys® Vitamin D total test. A total of 226 patients with biopsy-positive sarcoidosis were analyzed. The average median value of serum vitamin D was 9.47 mg/L, suggesting severe deficiency. Statistically significant correlation was found in patients with chronic disease and low levels of serum vitamin 25(OH)D (Chi-Square=6.044; df=2; p=0.014). The patient group with vitamin D serum levels higher than 20 mg/L showed higher levels of the mean forced vi tal capacity (FVC) by 380 mL, and forced expiratory volume in one second (FEV1) by 220 mL, when compared to the patient group with lower serum vitamin D. A statistically significant role was established for serum vitamin 25(OH)D levels as the predictor of fatigue (R2=0.878; p=0.038 (b=0.216)) and depression in patients with sarcoidosis (R2=0.80; p=0.000 (b=0.391)). The insufficiency of 25(OH)D seems to be an important factor in predicting the course of chronic disease, significant lung function impairments and cognitive failures such as fatigue and depression. The fact that the majo rity of the analyzed sarcoidosis patients had totally deficient serum 25(OH)D levels made this finding even more notable.
Analytical methods and performance of the immunoassay methods for determination of vitamin d in comparison to mass spectrometry / Analitičke metode i izvođenje imunometrijskih određivanja vitamina d u poređenju sa masenom spektrometrijom
Authors: Babić Nikolina 
Published: April 2013

Summary
Demand for vitamin D testing has been on a constant rise worldwide, partially due to mounting evidence linking vitamin D status to overall health and well-being. Currently available assays measure 25-hydroxy vitamin D (25-OHD), a major circulating form of vitamin D. Available methodologies include immunoassays and mass spectrometry based methods (LC-MS/MS). Until recently, the only immunoassays available for diagnostic use in the US have been DiaSorin radioimmunoassay (RIA) and an automated immunoassay on a LIAISON® platform. Within the last year, Siemens and Abbott successfully launched immuno - assays for determination of total vitamin D on their respective automated platforms, Centaur® and ARCHITECT®. Development of robust and precise Vitamin D immunoassays has historically been plagued with difficulty. One of the major challenges is development of specific antibodies against such a small antigen. Vitamin D is also highly hy - drophobic molecule predominantly bound to vitamin D binding protein (DBP). It is likely, therefore, that immuno - assays might be affected to varying extent by the DBP concentration. Adoption of LC-MS/MS into clinical laboratories has enabled development of accurate and almost fully automated methods that could handle increasing volume demands, especially in large volume reference laboratories. Smaller to mid-size hospital laboratories as well as physician offices have neither funds nor technical expertise to implement LC-MS/MS based testing. Our laboratory at the University of Chicago Medical Center has also seen in - crease in vitamin D volume and currently performs close to 20,000 25-OHD assays per year. We have recently deve - loped an LC-MS/MS method for quantitation of 25-OHD2 (obtained from plant sources) and 25-OHD3 (endogenous and animal sources). Prior to acquisition of LC-MS/MS instrument, we performed 25-OHD analysis by RIA. Du - ring the transition period, we encountered several challenges, including the necessity to streamline sample preparation as well as the bias introduced by calibration dif ferences. We chose to match our LC-MS/MS method to the RIA method in order to make this transition transparent to the clinician. Most immunoassays available today are acceptable for clinical use and might be method of choice for smaller laboratories. Larger clinical laboratories and aca demic institutions that possess technical expertise, particularly the ones with large pediatric population where assay sensitivity and specificity may be important, might find LC-MS/MS methodology a more suitable choice.
Effects of High but Non-Toxic Dietary Intake of Selenium and Copper on Indices of the Antioxidant Defence System and on Accumulation of Trace Elements in Chicks
Authors: Apsīte Mirdza , Bērziņa Nadežda , Basova Natālija 
Published: April 2013

Abstract
Lohman Brown chickens with age from the 1stto 35thday received the food with high doses ofselenium (Se1 mg/kg), copper (Cu100 mg/kg), or both elements (Se1 + Cu100). Live weight increaseof all three experimental chicken groups was by 9.3, 12.9 and 8.1%, respectively, in comparisonwith the control. The concentration of selenium in the blood of the Se1 group chickenswas by 45.5, in liver by 63.4 and in kidney by 19.7% higher that in organs of control group chickens.Selenium accumulation in organs of Se1 group chickens was highly correlated with increaseof glutathionperoxidase activity in blood (r = 0.90) and in liver (r = 0.85) and with decrease of glutathioneconcentration in liver. In Cu100 group chickens, copper concentration increased by 11.7in blood, in liver by 23.7, and in kidney by 19.9%. Together with more intensive excretion of glutathionefrom hepatocytes, copper concentration in bile increased by 17.7% compared to that incontrol group chickens. Also wing feathers participated in the regulation of copper homeostaticbalance, as copper concentration in feathers increased by 66.7%. The concentration of malondialdehidein liver of chickens from all groups was similar (43.5-45.2 μmol·g-1wet wt.), indicatingthat overload of selenium and copper did not cause profuse production of oxyradicals in the organism.Increased accumulation of selenium and copper in chickens influenced biochemical regulationof iron, zinc and cadmium deposition in liver, kidney, tibia and feather, changing therelations between Se and Fe, Se and Cd, Cu and Fe, Cu and Zn, and Cu and Cd concentrations.The analysis indicates increased tolerance of chicken to loads of selenium (1 mg/kg) and copper(100 mg/kg) doses
The Eurasian Reed Warbler (Acrocephalus Scirpaceus) Breeding in Egypt – A New Evidence?
Authors: Stêpniewska Katarzyna , Ożarowska Agnieszka 
Published: April 2013

Abstract
Stêpniewska K., O¿arowska A. 2012. The Eurasian Reed Warbler (Acrocephalus scirpaceus)
breeding in Egypt - a new evidence? Ring 34: 45-50.
To date, the documented breeding range of the Eurasian Reed Warbler in Egypt is limited to the Nile Delta. In March and September 2001 two females with brood patches were caught in the Wadi El Rayan Protected Area (30°19’E, 29°12’N) in the Western Desert of Egypt. These records, if accepted, might shift the southern border of the breeding range of Reed Warblers in Egypt west of the Nile Delta. The two individuals were the only records of breeding Reed Warblers in Wadi El Rayan, suggesting that the breeding population is small. It is possible that the population has been established recently because artificial lakes were created in Wadi El Rayan in 1973. The studies during the breeding season are essential to determine if such probable breeders demonstrate a new, but permanent breeding population or only ephemeral incidents, as well as to collect the data on the number, breeding biology and biometrical characteristics of such local populations at the southern limit of the world breeding range of the Reed Warbler.
ICT-Enabled Climate Change Education and Children Rights
Authors: Makrakis Vassilios , Gkotzos Dimitrios , Larios Nikolaos 
Published: April 2013

Abstract
This paper deals with a web-based learning environment that introduces primary school learners into the issue of children’s rights and climate change education. The methodological approach used is based on critical pedagogy and hypermedia technology. Through open source learning technologies and authentic learning activities that are enriched by open education resources and learning objects largely elicited from the Web, learners are being informed and construct knowledge related to six key areas of children’s rights affected by climate change.
Teacher Education for Sustainability in Network Society: Combining Digital and Sustainability Literacies
Authors: Huckle John 
Published: April 2013

Abstract
How should teacher education for sustainability (TEfS) respond to new information and communication technologies that can enable new forms of social and environmental relations and new forms of pedagogy? To answer that question, this article will consider the potential of Web 2.0 technologies or social media to enrich the content and pedagogy of education for sustainable development in both university and school classrooms. It will suggest that teachers should be introduced to critical social theory that seeks to explain the role of these new technologies in the recent wave of capitalist development that precipitated economic and ecological crisis, and their potential to bring about more sustainable alternatives. Such alternatives will be based on more radical and deliberative forms of democracy and citizenship enabled by the new technologies, and TEfS should equip teachers to explore these through appropriate forms of citizenship education and model them in their classrooms via new forms of critical pedagogy. Such ideas as those of Erik Olin Wright on real utopias and Manuel Castells on network society provide such TEfS with appropriate theory, while consideration of how YouTube videos might be used to develop critical digital and sustainability literacies in the classroom, illustrates how such theory might be related to practice.
Pedagogy, Places And People
Authors: Wade Ros 
Published: April 2013

Abstract
The paper will explore the potential of new technologies in helping educators to play an active role in creating and promoting the learning that is needed for local and global communities to live sustainably. In particular, it will examine the potential of the virtual world to develop local and global communities for transformative learning for sustainable development. It is organised into three sections: 1) the need for new ways of knowing, learning and understanding; 2) the challenges an opportunities of the virtual world; 3) the role of virtual learning communities in education for sustainable education; 4) regional centres of expertise as a mobilising mechanism. Faced with the major challenges of climate change, environmental degradation, poverty and social inequality, it is clear that learning to live sustainably has never been more urgent. The credit crunch has thrown these into sharp relief and provided an opportunity to take stock of our current ways of organising the world economy which have led us to this unsustainable impasse. We are faced with a critical moment in world history which offers the chance to make the changes needed to set human beings on a path to a more sustainable future. In order to address these immense challenges, new forms of learning are needed, and the paper will argue that all educators, as responsible members of local and global communities, need to play key roles as agents for change. Globalisation and new technologies have changed the way we think about the world and about what constitutes the global and the local. It is clear that both local and global solutions must be found to address the serious dilemmas of the 21st century. This paper will see to examine the opportunities and challenges of the virtual world in enabling and supporting the development of effective ESD communities of practice.
Needles, China Cups, Books, and the Construction of the Victorian Feminine Ideal in Rhoda Broughton’S Not Wisely, but too Well and Elizabeth Gaskell’S North and South
Authors: Setecka Agnieszka 
Published: April 2013

Abstract
Considering Victorian presentation of women as angelic, that is, spiritual, beings, it is rather surprising how much their presence was manifested by material objects. Baskets of needlework, tea equipage and novels lying around in a parlour were an unmistakable sign of the house being occupied by women. Indeed, my contention is, the objects did not clutter Victorian interiors, either real or imagined, merely for practical reasons or to produce the “reality effect.” They are a material representation of the immaterial and function as metaphors for angelic women’s spiritual qualities. Rather than functioning merely as details to enhance the illusion of the real (and thus as elements of style) or simply reflecting the Victorian world (and thus as empty forms), material objects are essential in constructing a middle-class (feminine) identity. My paper concentrates on Rhoda Broughton’s Not wisely, but too well and Elizabeth Gaskell’s North and South with an attempt to show how objects help construct a feminine ideal and, simultaneously, reveal the ideal to be just a construction. Broughton’s Kate Chester and Gaskell’s Margaret Hale find themselves in situations where their middle-class status might be compromised. Still, they both manage to reassert their position through effectively manipulating the signs of middle-class respectability. The “flimsy and useless” things they surround themselves with point to their “essentially feminine” qualities. Yet, the very superfluity of the objects reveals their relation to the characters’ economic status. They are, then, the site where the material and immaterial meet, where the borders between the economic world and the domestic world blur.
The Development of Learner Autonomy Through Internet Resources and Its Impact on English Language Attainment
Authors: Pawlak Mirosław , Kruk Mariusz 
Published: April 2013

Abstract
Since the arrival of the Internet and its tools, computer technology has become of considerable significance to both teachers and students, and it is an obvious resource for foreign language teaching and learning. The paper presents the results of a study which aimed to determine the effect of the application of Internet resources on the development of learner autonomy as well as the impact of greater learner independence on attainment in English as a foreign language. The participants were 46 Polish senior high school students divided into the experimental group (N = 28) and the control (N = 18) group. The students in the experimental group were subjected to innovative instruction with the use of the Internet and the learners in the control group were taught in a traditional way with the help of the coursebook. The data were obtained by means questionnaires, interviews, learners’ logs, an Internet forum, observations as well as language tests, and they were analyzed quantitatively and qualitatively. The results show that the experimental students manifested greater independence after the intervention and they also outperformed the controls on language tests.