bluuebunny/crossref_metadata_2025_split huggingface dataset:
Short-term outcomes following elective transcatheter arterial embolization for splenic artery aneurysms: data from a nationwide administrative database
Authors: Naganuma Michio , Matsui Hiroki , Koizumi Jun , Fushimi Kiyohide , Yasunaga Hideo 
Published: September 2015

Background Splenic artery aneurysm (SAA) rupture is life-threatening. Although elective transcatheter arterial embolization (TAE) suggested low in-hospital death in previous studies, there has been no large multi-center study of elective TAE for SAA. Purpose To examine the short-term outcomes of TAE for splenic artery aneurysm (SAA) and analyze the factors associated with the outcomes, including liver cirrhosis, using a nationwide administrative inpatient database. Material and Methods We identified patients who received elective TAE with a principal diagnosis of SAA. We assessed the patient background characteristics, comprising age, sex, and specific co-morbidities, including liver cirrhosis. The outcomes included the rate of TAE-related complications (acute pancreatitis, splenic infarction, splenic abscess, or intraperitoneal hematoma), length of stay, and in-hospital mortality. Results Among 18.3 million inpatients in the database between July 2010 and March 2013, we identified 534 patients who received elective TAE for SAA at 229 participating hospitals. Fifty-four (10.1%) patients had liver cirrhosis. No in-hospital deaths were observed. Thirty-two (6.0%) patients had at least one TAE-related complication. A multivariate linear regression analysis revealed that liver cirrhosis was significantly associated with longer length of stay (9.5 days; 95% confidence interval [CI], 7.0–12.0 days; P < 0.001). A logistic regression analysis showed that liver cirrhosis was not significantly associated with TAE-related complications (odds ratio, 0.99; 95% CI, 0.29–3.39; P = 0.980). Conclusion The results revealed no in-hospital mortality and a low complication rate associated with elective TAE for SAA including liver cirrhosis patients.
Outcome of mechanical thrombectomy in the very elderly for the treatment of acute ischemic stroke: the real world experience
Authors: To Chiu Yuen , Rajamand Sina , Mehra Ratnesh , Falatko Stephanie , Badr Yaser , Richards Boyd , Qahwash Omar , Fessler Richard D 
Published: September 2015

Background Although initial studies of neuroendovascular intervention did not review benefit over intravenous thrombolytics (iv r-tPA), recent studies have suggested otherwise. Elderly patients (age ≥80 years) are typically excluded from clinical trials. Purpose To examine the utility of mechanical thrombectomy based on patient outcomes. Material and Methods All stroke-alert activations at our health system from January 2011 to June 2014 were examined. All patients aged ≥80 years who had undergone mechanical thrombectomy were identified. Clinical characteristics included physiologic imaging findings, use of intravenous thrombolytics, baseline and postoperative National Institute of Health Stroke Scale (NIHSS), thrombolysis in cerebral infarction scores (TICI), and discharge destination. Results Mean NIHSS on presentation was 18.2 (range, 6–31), and 13.3 (range, 3–30) post thrombectomy. Three (16.6%) patients received iv r-tPA, two (11.1%) had symptomatic intracranial hemorrhage. Eight (44.4%) died, eight (44.4%) were discharged to nursing homes, and two (11.7%) were discharged to inpatient rehab and subsequently home. Favorable outcome was achieved in five (27.7%) patients. Fourteen (77.7%) patients had physiologic imaging prior to intervention. Three (75%) of four patients who did not have physiologic imaging prior to thrombectomy died. Thirteen (66.6%) patients had TICI 3 recanalization. Conclusion Our study showed that although there remains a role of mechanical thrombectomy in the treatment of acute ischemic stroke in very elderly patients, it is associated with significant higher morbidity and mortality compared to younger patients, but should remain a very viable treatment option when quality of life is the most important consideration.
Self-Reduction of Displaced Bucket-Handle Medial Meniscal Tear in a 71-Year-Old Patient
Authors: Ciminero Matthew L. , Huntley Samuel R. , Ghasem Alexander D. , Pitcher John D. 
Published: September 2015

Background: Bucket-handle meniscal tears are rare in geriatric patients. Displaced bucket-handle meniscal tears are usually treated operatively. Due to the rarity of these tears in elderly patients and conflicting evidence regarding the use of arthroscopy versus conservative treatment, it is valuable to report the clinical presentation, treatment, and outcome of these injuries in elderly patients. Case Description: We describe a 71-year-old man who presented with an acute, displaced, magnetic resonance imaging (MRI)-confirmed right medial meniscal bucket-handle tear with mild effusion and no signs of degenerative joint disease. On physical examination, the patient was unable to fully extend the right leg due to locking of the knee. At 2-month follow-up, MRI showed mild degenerative changes and an anatomically reduced tear. At 6-month follow-up, the patient reported normal, pain-free knee function, and MRI showed the tear healing in anatomic position with minimal inferior surface changes and no effusion. He returned to his pain-free baseline level of physical activity. Literature Review: Upon review of the English literature, this 71-year-old patient is an exceptional case and one of the oldest patients reported to have sustained a displaced medial meniscal bucket-handle tear treated successfully with nonoperative means. Two reported cases of spontaneously reduced meniscal bucket-handle tears were found in the English literature, although both cases were seen in much younger males and involved the lateral meniscus. Clinical Relevance: This case suggests that in elderly patients with displaced medial meniscus bucket-handle tears that reduce spontaneously, the physician can safely and efficaciously use conservative, nonoperative management to achieve restoration of baseline knee function and anatomic meniscal healing while avoiding the risks of arthroscopic surgery. Surgical intervention for reduction without repair may be an available option, but no literature is present to direct care; however, complete documentation as in the current case would be instructive. Katz et al have reported that physical therapy was as efficacious as surgical intervention, although the specific displaced bucket-handle tear was not reported.
Sympathetic Fibre Sprouting in the Skin Contributes to Pain-Related Behaviour in Spared Nerve Injury and Cuff Models of Neuropathic Pain
Authors: Nascimento Francisney P. , Magnussen Claire , Yousefpour Noosha , Ribeiro-da-Silva Alfredo 
Published: September 2015

Background Cuff and spared nerve injury (SNI) in the sciatic territory are widely used to model neuropathic pain. Because nociceptive information is first detected in skin, it is important to understand how alterations in peripheral innervation contribute to pain in each model. Over 16 weeks in male rats, changes in sensory and autonomic innervation of the skin were described after cuff and SNI using immunohistochemistry to label myelinated (neurofilament 200 positive—NF200+) and peptidergic (calcitonin gene-related peptide positive—CGRP+) primary afferents and sympathetic fibres (dopamine β-hydroxylase positive—DBH+) Results Cuff and SNI caused an early loss and later reinnervation of NF200 and CGRP fibres in the plantar hind paw skin. In both models, DBH+ fibres sprouted into the upper dermis of the plantar skin 4 and 6 weeks after injury. Despite these similarities, behavioural pain measures were significantly different in each model. Sympathectomy using guanethidine significantly alleviated mechanical allodynia 6 weeks after cuff, when peak sympathetic sprouting was observed, having no effect at 2 weeks, when fibres were absent. In SNI animals, mechanical allodynia in the lateral paw was significantly improved by guanethidine at 2 and 6 weeks, and the development of cold hyperalgesia, which roughly paralleled the appearance of ectopic sympathetic fibres, was alleviated by guanethidine at 6 weeks. Sympathetic fibres did not sprout into the dorsal root ganglia at 2 or 6 weeks, indicating their unimportance to pain behaviour in these two models. Conclusions Alterations in sympathetic innervation in the skin represents an important mechanism that contributes to pain in cuff and SNI models of neuropathic pain.
Monitoring of serum lactate level during cardiopulmonary resuscitation in adult in-hospital cardiac arrest
Authors: Wang Chih-Hung , Huang Chien-Hua , Chang Wei-Tien , Tsai Min-Shan , Yu Ping-Hsun , Wu Yen-Wen , Hung Kuan-Yu , Chen Wen-Jone 
Published: September 2015

AbstractIntroductionSerum lactate level may correlate with no-flow and low-flow status during cardiac arrest. Current guidelines have no recommended durations for cardiopulmonary resuscitation (CPR) before transition to the next strategy. We hypothesized that the lactate level measured during CPR could be associated with the survival probability and accordingly be useful in estimating the optimal duration for CPR.MethodsWe conducted a retrospective observational study in a single medical centre and included adult patients who had suffered an in-hospital cardiac arrest between 2006 and 2012. We used multivariable logistic regression analysis to study the association of lactate level measured during CPR and outcomes. We used generalized additive models to examine the nonlinear effects of continuous variables and conditional effect plots to visualize the estimated survival probability against CPR duration.ResultsOf the 340 patients included in our analysis, 50 patients (14.7 %) survived to hospital discharge. The mean lactate level was 9.6 mmol/L and mean CPR duration was 28.8 min. There was an inverse near-linear relationship between lactate level and probability of survival to hospital discharge. A serum lactate level <9 mmol/L was positively associated with patient survival to hospital discharge (odds ratio 2.00, 95 % confidence interval 1.01-4.06). The optimal CPR duration may not be a fixed value but depend on other conditions.ConclusionsSerum lactate level measured during CPR could correlate with survival outcomes. A lactate level threshold of 9 mmol/L may be used as a reference value to identify patients with different survival probabilities and determine the optimal CPR durations.
In situ structure of FtsZ mini-rings in Arabidopsis chloroplasts
Authors: Johnson Carol B. , Long Zheng , Luo Zhiping , Shaik Rahamthulla S. , Sung Min Woo , Vitha Stanislav , Holzenburg Andreas 
Published: September 2015

AbstractChloroplasts are essential plant organelles that divide by binary fission through a coordinated ring-shaped division machinery located both on the outside and inside of the chloroplast. The first step in chloroplast division is the assembly of an internal division ring (Z-ring) that is composed of the key filamentous chloroplast division proteins FtsZ1 and FtsZ2. How the individual FtsZ filaments assemble into higher-order structures to form the dividing Z-ring is not well understood and the most detailed insights have so far been gleaned from prokaryotic FtsZ. Here, we present in situ data of chloroplast FtsZ making use of a smaller ring-like FtsZ assembly termed mini-rings that form under well-defined conditions. Structured illumination microscopy (SIM) permitted their mean diameter to be determined as 208 nm and also showed that 68 % of these rings are terminally attached to linear FtsZ filaments. A correlative microscopy-compatible specimen preparation based on freeze substitution after high-pressure freezing is presented addressing the challenges such as autofluorescence and specific fluorescence attenuation. Transmission electron microscopy (TEM) and scanning TEM (STEM) imaging of thin sections exhibited ring-like densities that matched in size with the SIM data, and TEM tomography revealed insights into the molecular architecture of mini-rings demonstrating the following key features: (1) overall, a roughly bipartite split into a more ordered/curved and less ordered/curved half is readily discernible; (2) the density distribution in individual strands matches with the X-ray data, suggesting they constitute FtsZ protofilaments; (3) in the less ordered half of the ring, the protofilaments are able to assemble into higher-order structures such as double helices and supercoiled structures. Taken together, the data suggest that the state of existence of mini-rings could be described as metastable and their possible involvement in filament storage and Z-ring assembly is discussed.
Was kann Coaching von Mentoring lernen?
Authors: Höher Friederike 
Published: September 2015

Zusammenfassung
Aus der Mentoring-Forschung und besonders einem aktuellen Ansatz zum vernetzten Lernen im Mentoring ergeben sich einige Anregungen für Coaching, seine Evaluation und Wirksamkeitsforschung: Während Evaluationen von Coaching seine Erfolge für die Coachees und zum Teil auch seine Auswirkungen auf das organisationale Umfeld berücksichtigen, thematisiert die neuere Mentoring-Forschung zunehmend ebenfalls die Auswirkungen des Mentorings auf die Mentor/innen und reflektiert damit eine Entwicklung des Mentoring-Verständnisses in Richtung wechselseitiger Lern- und Entwicklungsbeziehungen. Da die Mentorenrolle mit der des Coachs zum Teil vergleichbar ist, wird dieser Gedankengang hier für die Wirksamkeitsforschung von Coaching aufgegriffen.
Ausgangspunkt der Überlegungen ist eine Untersuchung zum vernetzten Lernen im Mentoring in einer Langzeitperspektive, durch die die Effekte des Mentorings für beide Seiten, Mentees und Mentorinnen sehr deutlich werden.
Ruling the Colonies with sound: Documentary, technology and noise in Cronache dell’Impero
Authors: Fidotta Giuseppe 
Published: September 2015

Abstract
In 1937, the state-funded Istituto LUCE realized Cronache dell’Impero/Chronicles of the Empire, a short-lived series of documentaries aimed at attesting the activities the Regime was carrying out in the recently conquered East-Italian African territories. Attempting to go beyond the exoticism and clichéd representations usually employed in colonial documentaries, the series resorts to modernist strategies in order to highlight the value of the so-called civilizing mission. By tracing how these strategies were configured, this article looks specifically at the rhetorical use of sound and technology as a means for contributing to the propaganda purposes of the series, primarily the formation of a colonial consciousness. In this respect, technology and sound operate within a symbolic domain in which modernization and other colonial outcomes hinge on the allegedly transformative power of the Regime. Their visual and aural representations belong to the tradition of the political, avant-garde and documentary film practice.
Migration, prostitution and the representation of the black female subject in Nigerian video films about Italy
Authors: Jedlowski Alessandro 
Published: September 2015

Abstract
Much contemporary images of black women in Italian media are marked by the legacy of colonialist propaganda and tend to perpetuate a representation of black women as passive eroticized objects of the white male gaze. In this sense, Ponzanesi’s call for ‘new and less biased representations, which could help to assess the multiple subject positions that black identities now occupy’ is still relevant. This article responds to this call by analysing two Nigerian video films that thematize migration and prostitution trafficking in Italy. By highlighting the complexity of the processes of ‘subjectivation’ taking place throughout the migratory process, these videos invite their viewers to look at the postcolonial subject’s responsibility in shaping the world in which she lives, and offer a representation of the black female subject that is able to go beyond the voyeuristic attitude that characterizes much of the existing contemporary Italian visual culture surrounding this topic.
Nonsmooth and level-resolved dynamics illustrated with a periodically driven tight-binding model
Authors: Zhang Jiang Min , Haque Masudul 
Published: September 2015

Abstract
We point out that in the first-order time-dependent perturbation theory, the transition probability may behave nonsmoothly in time and have kinks periodically. Moreover, the detailed temporal evolution can be sensitive to the exact locations of the eigenvalues in the continuum spectrum, in contrast to coarse-graining ideas. Underlying this nonsmooth and level-resolved dynamics is a simple equality about the sinc function sinc x ≡ sin x/x. These physical effects appear in many systems with approximately equally spaced spectra, and are also robust for larger amplitude coupling beyond the domain of perturbation theory. We use a one-dimensional periodically driven tight-binding model to illustrate these effects, both within and outside the perturbative regime.
Impact of National Board for the Professional Teaching Standards (NBPTS) certification on student achievement
Authors: Irvine Belson Sarah , Husted Thomas A 
Published: September 2015

A growing number of teachers have undertaken National Board for Professional Teaching Standards (NBPTS) certification training since its inception over twenty-five years ago. Previous empirical research on the impact of NBCTs on student performance has focused on state or district-level exams in individual states and found mixed results. This study examines the relationship between National Board Certified Teachers (NBCTs) and student achievement on the reading and math assessments of the National Assessment of Educational Progress (NAEP). We argue that achievement can be affected both directly by the certified teacher and indirectly as NBCTs provide mentoring to colleagues and assume school leadership positions. This study focuses on a nationally representative assessment to measure student achievement rather than state- or district-level assessment exams. We find that the percentage of National Board certified teachers in a state is positively related to scores on state-level NAEP Reading and Math assessments.
Extent of QTL Reuse During Repeated Phenotypic Divergence of Sympatric Threespine Stickleback
Authors: Conte Gina L , Arnegard Matthew E , Best Jacob , Chan Yingguang Frank , Jones Felicity C , Kingsley David M , Schluter Dolph , Peichel Catherine L 
Published: September 2015

AbstractHow predictable is the genetic basis of phenotypic adaptation? Answering this question begins by estimating the repeatability of adaptation at the genetic level. Here, we provide a comprehensive estimate of the repeatability of the genetic basis of adaptive phenotypic evolution in a natural system. We used quantitative trait locus (QTL) mapping to discover genomic regions controlling a large number of morphological traits that have diverged in parallel between pairs of threespine stickleback (Gasterosteus aculeatus species complex) in Paxton and Priest lakes, British Columbia. We found that nearly half of QTL affected the same traits in the same direction in both species pairs. Another 40% influenced a parallel phenotypic trait in one lake but not the other. The remaining 10% of QTL had phenotypic effects in opposite directions in the two species pairs. Similarity in the proportional contributions of all QTL to parallel trait differences was about 0.4. Surprisingly, QTL reuse was unrelated to phenotypic effect size. Our results indicate that repeated use of the same genomic regions is a pervasive feature of parallel phenotypic adaptation, at least in sticklebacks. Identifying the causes of this pattern would aid prediction of the genetic basis of phenotypic evolution.
A exigibilidade de autorização de funcionamento por empresas matrizes para atuar em estado onde não possuem filiais
Authors: De Souza Delgado Joedson 
Published: September 2015

Como forma contemporânea de atuação da Administração Pública, a Agência Nacional de Vigilância Sanitária (Anvisa) tem por finalidade institucional promover a tutela da saúde da população através do controle sanitário dos produtos e serviços de interesse à saúde por intermédio da atividade regulatória. Analisa-se, então, a Resolução da Diretoria Colegiada (RDC) n. 345, de 16/12/2002 da Anvisa, ainda em vigor, que aprovou o regulamento técnico no que concerne à abrangência e validade de Autorização de Funcionamento de Empresa (AFE) para prestadoras de serviços, a qual entende limitada ao Estado ou Distrito Federal onde a empresa realiza a sua prestação de serviço. É pertinente uma reflexão sobre este processo, visto que o aludido normativo no art. 5º e parágrafos de seu Anexo I estabeleceram, de forma clara, que a AFE tem a sua abrangência limitada ao Estado ou Distrito Federal onde se realize a prestação do serviço. A partir de revisão de literatura verifica-se o impacto desse instrumento normativo nas atividades de fomento.Defende-se que não é da competência da Anvisa impor às empresas prestadora de serviço que constituam filiais com o fito de se adequarem ao regramento e, assim, obter a Autorização, nas hipóteses e condições estabelecidas pela norma técnica respectiva.
Direito à saúde, Poder Judiciário e Orçamento Público.
Authors: Mazza Fábio Ferreira 
Published: September 2015

Passados mais de vinte anos desde a promulgação da Constituição Federal de 1988 (que institucionalizou as regras orçamentárias em nosso país), e mais de dez anos de vigência da Lei de Responsabilidade Fiscal (Lei nº 101/2000 que trata da responsabilidade na gestão fiscal), em que medida as decisões judiciais junto às prestações de serviços de saúde não observam as leis orçamentárias podendo, desta forma, comprometer o orçamento em saúde e prejudicar a concretização da política de saúde universal planejada? O artigo em questão serve como um alerta para que nos atentemos para a forma em que o Poder Judiciário vem decidindo as demandas na área da saúde, além de apontar para a necessidade de uma maior discussão e a realização de um estudo de maior amplitude no campo do direito à saúde e orçamento público. O artigo foi realizado mediante pesquisa bibliográfica e documental. A pesquisa documental e bibliográfica teve como bas e a literatura referente ao direito fundamental social à saúde, no marco do Estado Democrático de Direito, bem como o fenômeno da judicialização da saúde e da institucionalização das finanças públicas no País, a partir da Constituição de 1988.