bluuebunny/crossref_metadata_2025_split huggingface dataset:
Folate metabolism genes, dietary folate and response to antidepressant medications in late‐life depression
Authors: Jamerson Brenda D. , Payne Martha E. , Garrett Melanie E. , Ashley‐Koch Allison E. , Speer Marcy C. , Steffens David C. 
Published: December 2012

ObjectiveThe primary aims of this study were to (i) determine whether folate metabolism genetic polymorphisms predict age of onset and occurrence of late life depression; and (ii) determine whether folate metabolism genetic polymorphisms predict response to antidepressant medications in late‐life depression.MethodsThis study used the Conte Center for the Neuroscience of Depression and the Neurocognitive Outcomes of Depression in the Elderly Study database, which includes individuals aged ≥60. The folate nutrition assessment was determined by the Block Food Frequency Questionnaire. Genotype was evaluated for 15 single nucleotide polymorphisms from 10 folate metabolism genes. Logistic regression models were used to examine genetic polymorphisms and folate estimates with association with depression age of onset and remission status.ResultsThere were 304 Caucasians in the database, 106 of these were not depressed and 198 had a diagnosis of depression. There were no significant differences between remitters and non‐remitters in age, sex or estimated folate intakes. There were no folate estimates or folate metabolism gene single nucleotide polymorphisms that significantly predicted age of onset of depression or occurrence of depression. Methionine synthase reductase (MTRR) A66G (rs1801394) was significantly associated with remission status (p = 0.0077) such that those with the AA genotype were 3.2 times as likely as those with the GG genotype to be in remission (p = 0.0020). Methylenetetrahydrofolate reductase A1298C (rs1801131) achieved a borderline significance for association with remission status (p = 0.0313).ConclusionThe major finding from this study is that the MTRR A66G genotype predicts response to selective serotonin reuptake inhibitor antidepressants in late life depression. Copyright © 2012 John Wiley & Sons, Ltd.
Advanced treatment of biologically pretreated coking wastewater by electrochemical oxidation using Ti/RuO2–IrO2 electrodes
Authors: He Xuwen , Chai Zhen , Li Fuping , Zhang Chunhui , Li Dong , Li Jing , Hu Jianlong 
Published: December 2012

AbstractBackgroundElectrochemical oxidation has attracted wide attention in wastewater treatment because of its strong oxidation performance and ease of control. This work investigated the feasibility of electrochemical treatment using a Ti/RuO2–IrO2 anode as an advanced treatment of coking wastewater. The influential operating factors including current density (9.6–108.2 mA cm−2) and electrode gap (0.5–2.5 cm) were evaluated.ResultsThe current density and electrodes gap had significant effects on COD and NH4+‐N removal and the energy consumption. The degradation of COD and NH4+‐N followed pseudo‐first‐order kinetics. In most experiments, high levels of NH4+‐N removal (NH4+‐N removal ratio > 95%) was achieved along with moderate mineralization (COD removal ratio: 60–80%). COD (178.0–285.0 mg L‐1) and NH4+‐N (55.0–76.0 mg L‐1) were degraded by 62% and 96%, respectively, at the optimum conditions (electrode gap: 0.5 cm, current density: 15.6 mA cm−2) after 60 min treatment. Under this optimal condition, the corresponding energy consumption was 8.60 kWh m‐3 for effluent meeting the discharge standards. Furthermore, gas chromatography–mass spectrometry (GC‐MS) analysis indicated that this technique could be employed to eliminate bio‐refractory and toxic compounds such as phenanthrene, indole, quinoline and pyrimidine in coking wastewater.ConclusionTi/RuO2–IrO2 anode systems were confirmed to be effective in advanced treatment of biologically pretreated coking wastewater. © 2012 Society of Chemical Industry
Direct in vitro comparison of six three‐dimensional positive contrast methods for susceptibility marker imaging
Authors: Vonken Evert‐jan P.A. , Schär Michael , Yu Jing , Bakker Chris J.G. , Stuber Matthias 
Published: December 2012

PurposeTo compare different techniques for positive contrast imaging of susceptibility markers with MRI for three‐dimensional visualization. As several different techniques have been reported, the choice of the suitable method depends on its properties with regard to the amount of positive contrast and the desired background suppression, as well as other imaging constraints needed for a specific application.Materials and MethodsSix different positive contrast techniques are investigated for their ability to image at 3 Tesla a single susceptibility marker in vitro. The white marker method (WM), susceptibility gradient mapping (SGM), inversion recovery with on‐resonant water suppression (IRON), frequency selective excitation (FSX), fast low flip‐angle positive contrast SSFP (FLAPS), and iterative decomposition of water and fat with echo asymmetry and least‐squares estimation (IDEAL) were implemented and investigated.ResultsThe different methods were compared with respect to the volume of positive contrast, the product of volume and signal intensity, imaging time, and the level of background suppression. Quantitative results are provided, and strengths and weaknesses of the different approaches are discussed.ConclusionThe appropriate choice of positive contrast imaging technique depends on the desired level of background suppression, acquisition speed, and robustness against artifacts, for which in vitro comparative data are now available. J. Magn. Reson. Imaging 2013;38:344–357. © 2013 Wiley Periodicals, Inc.
Comparison of DSC‐MRI post‐processing techniques in predicting microvascular histopathology in patients newly diagnosed with GBM
Authors: Essock‐Burns Emma , Phillips Joanna J. , Molinaro Annette M. , Lupo Janine M. , Cha Soonmee , Chang Susan M. , Nelson Sarah J. 
Published: December 2012

PurposeTo evaluate which common post‐processing method applied to gradient‐echo DSC‐MRI data, acquired with a single gadolinium injection and low flip‐angle, most accurately reflects microvascular histopathology for patients with de novo, treatment‐naive glioblastoma multiforme (GBM).Materials and MethodsSeventy‐two tissue samples were collected from 35 patients with treatment‐naive GBM. Sample locations were co‐registered to preoperative gradient‐echo dynamic susceptibility contrast (DSC) MRI acquired with 35° flip‐angle and 0.1 mmol/kg gadolinium. Estimates of blood volume and leakiness at each sample location were calculated using four common postprocessing methods (leakage‐corrected nonlinear gamma‐variate, non‐parametric, scaled MR‐signal, and unscaled MR‐signal). Tissue sample microvascular morphology was characterized using Factor VIII immunohistochemical analysis. A random‐effects regression model, adjusted for repeated measures and contrast‐enhancement (CE), identified whether MR parameter estimates significantly predicted IHC findings.ResultsElevated blood volume estimates from nonlinear and non‐parametric methods significantly predicted increased microvascular hyperplasia. Abnormal microvasculature existed beyond the CE‐lesion and was significantly reflected by increased blood volume from nonlinear, non‐parametric, and scaled MR‐signal analysis.ConclusionThis study provides histopathological support for both non‐parametric and nonlinear post‐processing of low flip‐angle DSC‐MRI for characterizing microvascular hyperplasia within GBM. Non‐parametric analysis with a single gadolinium injection may be a particularly useful strategy clinically, as it requires less computational expense and limits gadolinium exposure. J. Magn. Reson. Imaging 2013;38:388–400. © 2013 Wiley Periodicals, Inc.
Effects of deposition parameters on hardness and lubrication properties of thin MoS2 films
Authors: Vierneusel B. , Tremmel S. , Wartzack S. 
Published: December 2012

AbstractThe purpose of the present study is the development of a sputtered MoS2‐coating suitable for the use in humid atmospheres. Influences of the process parameters argon pressure, temperature, distance between substrate and target and bias voltage on tribological properties and hardness are presented. By means of these parameter studies, different microstructures with widely varying wear behavior were achieved. Life cycle tests show that exclusively basal oriented coatings with dense, non columnar structures show the highest durability and a hardness of about 400 HV 0.01. However, dendritic needle like structures show lower endurance and lower hardness (<100 HV 0.01). Films with a comparatively high hardness (up to 800 HV 0.01) exhibit lowest sliding distances until failure due to an appearance of spalling in the ball‐on‐disc tests. Those coatings also show a dense but amorphous structure and sulfur deficiencies. Consolidation during sputtering, i. e. film hardness and porosity, can be controlled by certain process parameters and is probably affected by varying amounts of internal stress.
Coordination mechanisms for a three‐stage reverse supply chain to increase profitable returns
Authors: Zeng Amy Z. 
Published: December 2012

AbstractIn this article, we consider a generic electronic product that can be remanufactured or recycled at the end of its life cycle to generate new profit. We first describe the product return process and then present a customer segmentation model to capture consumers' different behaviors with respect to product return so that the retailer can work more effectively to increase the return volume. In regard to the collaboration between the retailer and the manufacturer, we explore a revenue‐sharing coordination mechanism for achieving a win‐win outcome. The optimality and sensitivity of the critical parameters in four strategies are obtained and examined both theoretically and numerically, which generate insights on how to manage an efficient consumer‐retailer‐manufacturer reverse supply chain, as well as on the feasibility of simplifying such a three‐stage chain structure. © 2012 Wiley Periodicals, Inc. Naval Research Logistics, 2013
A three‐dimensional atomistic‐based process zone model simulation of fragmentation in polycrystalline solids
Authors: Ren Bo , Li Shaofan 
Published: December 2012

SUMMARYA three‐dimensional atomistic‐based process zone model (APZM) is used to simulate high‐speed impact induced dynamic fracture process such as fragmentation and spall fracture. This multiscale simulation model combines the Cauchy–Born rule, colloidal crystal process model, and micromechanics homogenization technique to construct constitutive relations in both grains and grain boundary at mesoscale. The proposed APZM has some inherent advantages to describe mechanical behaviors of polycrystalline solids. First, in contrast to macroscale phenomenological constitutive models, the APZM takes into account atomistic binding energy and atomistic lattice structure. In particular, the electron density related embedded atom method (EAM) potential has been adopted to describe interatomistic interactions of metallic polycrystalline solids in bulk elements; second, a mixed type of EAM potential and colloidal crystal depletion potential is constructed to describe heterogeneous microstructure in the process zone; third, the atomistic potential in both bulk material and process zone has the same atomistic origin, and hence, the bulk and process potentials are self‐consistent. The simulation of dynamic fracture process of a cylinder made of aluminum powder metallurgy (P/M) alloy during high‐speed impact/penetration is carried out, and numerical results demonstrate that APZM finite element method has remarkable ability to accurately capture complex three‐dimensional fragmentation formation and damage morphology. Copyright © 2012 John Wiley & Sons, Ltd.
Look fast: Crystallization of conjugated molecules during solution shearing probed in‐situ and in real time by X‐ray scattering
Authors: Smilgies Detlef‐M. , Li Ruipeng , Giri Gaurav , Chou Kang Wei , Diao Ying , Bao Zhenan , Amassian Aram 
Published: December 2012

AbstractHigh‐speed solution shearing, in which a drop of dissolved material is spread by a coating knife onto the substrate, has emerged as a versatile, yet simple coating technique to prepare high‐mobility organic thin film transistors. Solution shearing and subsequent drying and crystallization of a thin film of conjugated molecules is probed in situ using microbeam grazing incidence wide‐angle X‐ray scattering (μGIWAXS). We demonstrate the advantages of this approach to study solution based crystal nucleation and growth, and identify casting parameter combinations to cast highly ordered and laterally aligned molecular thin films.magnified image(© 2012 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Adjusting to BRICs in Glass Houses: Replacing Obsolete Institutions and Business Models
Authors: Aggarwal Raj 
Published: December 2012

AbstractGlobal adjustment to the rise of the BRIC and other emerging economies is an important challenge for firms in the advanced economies. Emerging market firms increasingly trade and invest globally while monetary imbalances continue to rise and hobble advanced economy firms. Advanced country firms feel like they live in glass houses as the tectonic forces of technology, demographics, globalization, sustainability, and climate change force obsolescence in their business models. In this article, this overseas projection of economic power by the rising new economies is illustrated by the Indian and Chinese overseas economic expansion focused on Africa. This analysis shows that noneconomic state‐driven entities are likely to be a significant part of the rise of South‐South economic trade and investment flows and it poses theoretical and practical problems for existing market‐based economic and geopolitical institutions. Global adjustment to these new realities is also challenging as existing multilateral institutions seem to be inadequate. These changes in the global environment have significant implications for policy makers and managers of global companies. © 2013 Wiley Periodicals, Inc.
Trouble Ahead: Derailment Is Alive and Well
Authors: Zhang Yi , Leslie Jean Brittain , Hannum Kelly M. 
Published: December 2012

AbstractDerailment is a common phenomenon in organizations; however, managers' derailment can be prevented if the phenomenon is well understood. Derailed managers often have impressive track records and are solidly established within their organizations, but something goes wrong along the way. In this article, we review the dynamics and causes of derailment. We then report survey results from over 2,500 respondents across five countries with differences noted by level, industry, and country. Finally, we describe actions to prevent derailment. © 2013 Wiley Periodicals, Inc.
Non-residual Sr of the sediments in Daihai Lake as a good indicator of chemical weathering
Authors: Zeng Yan , Chen Jingan , Xiao Jule , Qi Liang 
Published: December 2012

AbstractThe Rb/Sr ratio of lake sediments has been demonstrated to be a potential indicator of chemical weathering by increasing work. However, Rb and Sr in lake sediments are derived from both chemical weathering and physical erosion. Rb and Sr of different forms in lake sediments may record different environmental processes and information. In this study, the variation patterns of Rb and Sr of different forms in sediments of Daihai Lake were investigated. The results show that Rb and Sr of different forms display noticeably different variation patterns due to their different sources and associated environmental processes. Using the Rb/Sr ratios of bulk lake sediments to reflect chemical weathering is not accurate. The non-residual Sr of the sediments without detrital carbonates, representing the Sr leached from the catchment, can be used as an index of chemical weathering because the weathering of Sr minerals is very sensitive to climate change, and the non-residual Sr content of the sediment is determined more by Sr2 + influx than by the physicochemical conditions of lake water. The correspondence between the non-residual Sr and TIC/TOC in Daihai Lake also indicates that the non-residual Sr of the sediments is a good indicator of chemical weathering in the catchment.
Evidence for large-amplitude biome and climate changes in Atlantic Canada during the last interglacial and mid-Wisconsinan periods
Authors: Fréchette Bianca , de Vernal Anne 
Published: December 2012

AbstractLast interglacial and mid Wisconsinan pollen data from sedimentary sequences of Cape Breton Island in Atlantic Canada were analyzed to reconstruct biome and climate conditions. Our results show warm and humid climate with mean annual temperature 6–7°C higher than today, up to 15–20% more sunshine and significantly longer growing season that fostered growth of temperate trees during the optimum of the last interglacial. The northern limit of the deciduous forest biome was then about 500 km north of its modern limit. Towards the end of the interglacial the deciduous forest was replaced by conifer/hardwood forest and boreal forest. Climate was then similar to modern. The transition from interglacial to glacial was marked by a change towards coniferous forest related to colder and dryer conditions. During the mid Wisconsinan, the development of forest tundra to boreal forest reflects migration of the Arctic Front and significant cooling with mean annual temperature anomalies of − 8 to − 12°C. The overall time series reflect large amplitude climate changes that point to high sensitivity of the southeastern Canadian margins, likely as a response to latitudinal shifts of the Gulf Stream and variable strength of the Labrador Current together with changes in large-scale atmospheric circulation pattern.
A Simple Method for Contact modelling in an Arbitrary frame of Reference within multi-Physics Software
Authors: Espino D. M. , Shepherd D.E.T. , Hukins D.W.L. 
Published: December 2012

AbstractA method to simulate contact between two boundaries of structures which are not aligned to predefined axes when using Comsol Multi-physics (v3.3, Comsol Ltd, Cambridge, UK) is presented. This method was developed because of limitations in the existing default contact modelling. Some of these limitations were recently addressed in a separate study; however, the method exploited symmetry across an axis of the coordinate system. The method presented here enables contact modelling with arbitrarily aligned structures within such a coordinate system. The contact method presented is then applied to a simple model with two deformable structures that come into contact, and compared over a range of positions. Results show a minimal variation in peak stress and contact pressure with model orientation, demonstrating that results are independent of orientation. Therefore, the contact method enables contact simulations in Comsol Multi-physics without assuming symmetry about an axis for contract. The method is compatible with the true transient contact method defined.
GRAIN FILLING OF DURUM WHEAT THROUGH ASSIMILATE REMOBILISATION UNDER SEMI-ARID CONDITIONS
Authors: LATIRI K. , LHOMME J. P. , LAWLOR D. W. 
Published: December 2012

SUMMARYIn a context of understanding the physiological mechanisms and cultivar traits which could improve durum wheat (Triticum durum) yield in water limited conditions, the paper focuses on the contribution of stored assimilates to grain growth and yield. A conceptual model describing the different fluxes of assimilate during the grain filling period is used together with a dataset from field experiments made in northern Tunisia during two growing seasons and under different conditions of water and nitrogen supply. Three types of behaviour have been encountered in relation to the balance between demand for assimilate and supply. Remobilisation of stored assimilates provides a buffer enabling grain growth to be maintained. Conditions at anthesis play an important role in determining the type of fluxes of assimilates. Grain number also plays a major role in short- or long-term remobilisation and grain number per ear increases short-term remobilisation. In rain-fed conditions, short-term remobilisation allows faster grain growth.
Multicultural voices: attitudes of older adults in the United States of America about elder mistreatment
Authors: ENGUIDANOS SUSAN M. , DELIEMA MARGUERITE , AGUILAR IRIS , LAMBRINOS JORGE , WILBER KATHLEEN H. 
Published: December 2012

ABSTRACTDespite international growth in policies to increase the identification and response to elder abuse and neglect, there remain considerable barriers to treating the problem. Some of these barriers may be attributed to how older adults from different racial/ethnic backgrounds define, experience and seek to remedy elder mistreatment. Using focus group discussions based on case vignettes, this paper examines how older adults from different racial and ethnic backgrounds in the United States of America perceive elder mistreatment. Five focus groups were conducted with African Americans, English-speaking Latinos, Spanish-speaking Latinos, non-Latino Whites and African American care-givers for older adults. While similar definitions and meanings of elder abuse were expressed across the different racial/ethnic groups, Latino participants introduced additional themes ofmachismo, respect, loveandearly interventionto stop abuse, suggesting that perceptions/beliefs about elder mistreatment are determined by culture and degree of acculturation in addition to race/ethnicity. Most differences in attitudes occurredwithingroups, demonstrating that perceptions vary by individual as well as by culture. In identifying scenarios that constitute elder mistreatment, some participants felt that certain cases of abuse are actually the persistence of intimate partner violence into old age. Participants also indicated that victims may prefer to tolerate mistreatment in exchange for other perceived benefits (e.g.companionship, security); and out of fear that they could be placed in an institution if mistreatment is reported. Findings suggest the need for person-centred intervention and prevention models that integrate the cultural background, care needs and individual preferences of older adults.
Avoiding Arrays of Odd Order by Latin Squares
Authors: ANDRÉN LINA J. , CASSELGREN CARL JOHAN , ÖHMAN LARS-DANIEL 
Published: December 2012

We prove that there is a constantcsuch that, for each positive integerk, every (2k+ 1) × (2k+ 1) arrayAon the symbols (1,. . .,2k+1) with at mostc(2k+1) symbols in every cell, and each symbol repeated at mostc(2k+1) times in every row and column isavoidable; that is, there is a (2k+1) × (2k+1) Latin squareSon the symbols 1,. . .,2k+1 such that, for eachi,j∈ {1,. . .,2k+1}, the symbol in position (i,j) ofSdoes not appear in the corresponding cell inA. This settles the last open case of a conjecture by Häggkvist. Using this result, we also show that there is a constant ρ, such that, for any positive integern, if each cell in ann×narrayBis assigned a set ofm≤ ρnsymbols, where each set is chosen independently and uniformly at random from {1,. . .,n}, then the probability thatBis avoidable tends to 1 asn→ ∞.