bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Use of an Anterior Abdominal Wall Peritoneal Flap in the Laparoscopic Repair of Vesicouterine Fistula
Authors: Tasdemir Nicel , Abali Remzi , Celik Cem , Yazici Cenk Murat , Akkus Didem 
Published: December 2014

Abstract
Vesicouterine fistula (VUF) is a rare type of genitourinary fistula. Lower-segment cesarean section is the leading cause of VUF. Patients mostly present with the classical triad of menouria, amenorrhea, and urinary incontinence, with the history of a previous cesarean section. Conservative management with catheterization and open, laparoscopic, and robotic surgeries are the prescribed treatment options. We present the case of a 35-year-old woman who presented with cyclical menouria and urinary incontinence. After diagnosis of VUF by cystoscopy, the laparoscopic approach was chosen. During the procedure, we used anterior abdominal wall peritoneum and adjacent adipose tissue interposition for the first time, instead of omental interposition, because of the unavailability of omentum. The postoperative period was uneventful, and the procedure was successful. In conclusion, the laparoscopic approach is feasible and the anterior abdominal wall peritoneal flap can be used instead of omentum for tissue interposition when the omentum is not available.
Predicting Clinical Outcomes of SARS‐CoV‐2 Drug Efficacy with a High‐Throughput Human Airway Microphysiological System
Authors: Lopez Quezada Landys , Mba Medie Felix , Luu Rebeccah J. , Gaibler Robert B. , Gabriel Elizabeth P. , Rubio Logan D. , Mulhern Thomas J. , Marr Elizabeth E. , Borenstein Jeffrey T. , Fisher Christine R. , Gard Ashley L. 
Published: August 2024

AbstractThe average cost to bring a new drug from its initial discovery to a patient's bedside is estimated to surpass $2 billion and requires over a decade of research and development. There is a need for new drug screening technologies that can parse drug candidates with increased likelihood of clinical utility early in development in order to increase the cost‐effectiveness of this pipeline. For example, during the COVID‐19 pandemic, resources were rapidly mobilized to identify effective therapeutic treatments but many lead antiviral compounds failed to demonstrate efficacy when progressed to human trials. To address the lack of predictive preclinical drug screening tools, PREDICT96‐ALI, a high‐throughput (n = 96) microphysiological system (MPS) that recapitulates primary human tracheobronchial tissue,is adapted for the evaluation of differential antiviral efficacy of native SARS‐CoV‐2 variants of concern. Here, PREDICT96‐ALI resolves both the differential viral kinetics between variants and the efficacy of antiviral compounds over a range of drug doses. PREDICT96‐ALI is able to distinguish clinically efficacious antiviral therapies like remdesivir and nirmatrelvir from promising lead compounds that do not show clinical efficacy. Importantly, results from this proof‐of‐concept study track with known clinical outcomes, demonstrate the feasibility of this technology as a prognostic drug discovery tool.
Wavelet Collocation Method for HIV‐1/HTLV‐I Co‐Infection Model Using Hermite Polynomial
Authors: Agrawal Khushbu , Kumar Sunil 
Published: August 2024

AbstractIn this study, the dynamic behavior of fractional order co‐infection model with human immunodeficiency virus type 1 (HIV‐1) and human T‐lymphotropic virus type I (HTLV‐I) is analyzed using operational matrix of Hermite wavelet collocation method. Also, the uniqueness and existence of solutions are calculated based on the fixed point hypothesis. For the fractional order co‐infection model, its positivity and boundedness are demonstrated. Furthermore, different types of Ulam‐Hyres stability are also discussed. The numerical solution of the model are obtained by using the operational matrix of the Hermite wavelet approach. This scheme is used to solve the system of nonlinear equations that are very fruitful and easy to implement. Additionally, the stability analysis of the numerical scheme is explained. The mathematical model taken in this work incorporates the biological characteristics of both HIV‐1 and HTLV‐I. After that all the equilibrium points of the fractional order co‐infection model are found and their existence conditions are explored with the help of the Caputo derivative. The global stability of all equilibrium points of this model are determined with the help of Lyapunov functions and the LaSalle invariance principle. Convergence analysis is also discussed. Hermite wavelet operational matrix methods are more accurate and convergent than other numerical methods. Lastly, variations in model dynamics are found when examining different fractional order values. These findings will be valuable to biologists in the treatment of HIV‐1/HTLV‐I.
The Molecular Landscape of Premature Aging Diseases Defined by Multilayer Network Exploration
Authors: Beust Cécile , Valdeolivas Alberto , Baptista Anthony , Brière Galadriel , Lévy Nicolas , Ozisik Ozan , Baudot Anaïs 
Published: August 2024

AbstractPremature Aging (PA) diseases are rare genetic disorders that mimic some aspects of physiological aging at an early age. Various causative genes of PA diseases have been identified in recent years, providing insights into some dysfunctional cellular processes. However, the identification of PA genes also revealed significant genetic heterogeneity and highlighted the gaps in this understanding of PA‐associated molecular mechanisms. Furthermore, many patients remain undiagnosed. Overall, the current lack of knowledge about PA diseases hinders the development of effective diagnosis and therapies and poses significant challenges to improving patient care.Here, a network‐based approach to systematically unravel the cellular functions disrupted in PA diseases is presented. Leveraging a network community identification algorithm, it is delved into a vast multilayer network of biological interactions to extract the communities of 67 PA diseases from their 132 associated genes. It is found that these communities can be grouped into six distinct clusters, each reflecting specific cellular functions: DNA repair, cell cycle, transcription regulation, inflammation, cell communication, and vesicle‐mediated transport. That these clusters collectively represent the landscape of the molecular mechanisms that are perturbed in PA diseases, providing a framework for better understanding their pathogenesis is proposed. Intriguingly, most clusters also exhibited a significant enrichment in genes associated with physiological aging, suggesting a potential overlap between the molecular underpinnings of PA diseases and natural aging.
Co‐Assembled Supramolecular Hydrogelators Enhance Glomerulogenesis in Kidney Organoids Through Cell‐Adhesive Motifs
Authors: van Sprang Johnick F. , Aarts Jasper G.M. , Rutten Martin G.T.A. , Rijns Laura , Tiemeijer Bart M. , Schotman Maaike J.G. , Dankers Patricia Y.W. 
Published: August 2024

AbstractSoluble biochemical agents are being employed to generate kidney organoids from human‐induced pluripotent stem cells. However, this soluble factor approach does not consider the effect of the mechanical environment on lineage commitment. Here, a mechanoresponsive nano‐environment with cell‐adhesive properties composed of supramolecular hydrogelators that co‐assemble into fibrous superstructures to form a transient network is presented, which is used to encapsulate kidney organoids. The delayed sol‐gel transition of the transient network enables fibrous superstructures to diffuse into the densely packed extracellular organoid space during the encapsulation procedure. This allows the mechanoresponsive matrix to induce a biological response beyond the organoid‐hydrogel border, and tune glomerulogenesis inside kidney organoids. In this manner, biomaterials are used as a complementary tool to soluble biochemical agents in tuning lineage commitment and refining organoid maturation.
Thermostable Tellurium Anchoring Enabling Robust Thermal and Electrochemical Stability for Pt3Co Intermetallic Fuel Cell Catalysts
Authors: Chen Yuanxin , Meng Zihan , Liu Fei , Zhang Aojie , Wang Xiaocan , Xiong Yifei , Tang Haibo , Tian Tian , Tang Haolin 
Published: August 2024

AbstractHighly active Pt‐based intermetallic nanoparticles (i‐NPs) loaded on stable supports have garnered considerable interest as promising oxygen reduction reaction (ORR) catalysts for proton‐exchange‐membrane fuel cells (PEMFCs). Herein, thermostable tellurium (Te) is vapor‐deposited onto commercial conductive carbon to anchor high‐temperature‐synthesized Pt3Co i‐NPs. Advanced characterization and density functional theory (DFT) calculations demonstrate that the binding energy of Pt 4f and Co 2p shift positively by 0.12 and 0.95 eV after the introduction of Te in carbon support, promoting the formation of Pt─Te bonds, which enhances the metal–support interactions (MSIs) in Pt3Co/Te‐C (with a more negative binding energy of −10.28 eV). The average size of well‐dispersed Pt3Co i‐NPs (≈3.9 nm) on Te─C is considerably smaller than that of Pt3Co i‐NPs (≈9.1 nm) on commercial carbon. The specific activity of Pt3Co/Te‐C decreases by only 1.5% after 100,000 ultra‐long voltage‐accelerated cycles, while the morphology remains almost unchanged. The membrane electrode assembly using Pt3Co/Te‐C as a cathode demonstrates impressive activity (power density of 2.32 W cm−2@4 A cm−2 and mass activity of 0.50 A mgPt−1@0.9 V) and robust durability (mass activity@0.9 V loss of 26% after 30,000 cycles with intact L12 ordered structure) in H2–O2 operation, significantly exceeding the DOE 2025 requirements.
Anion‐Engineering Toward High‐Voltage‐Stable Halide Superionic Conductors for All‐Solid‐State Lithium Batteries
Authors: Shen Liang , Li Jin‐Liang , Kong Wei‐Jin , Bi Chen‐Xi , Xu Pan , Huang Xue‐Yan , Huang Wen‐Ze , Fu Fang , Le Yi‐Cheng , Zhao Chen‐Zi , Yuan Hong , Huang Jia‐Qi , Zhang Qiang 
Published: August 2024

AbstractHalide solid electrolytes (SEs) are attracting strong attention as one of the compelling candidates for the next‐generation of inorganic SEs due to their high ionic conductivity. Nevertheless, unsatisfactory high‐voltage stability restricts the further applications of halide SEs. Herein, the anion‐engineering of F−/O2− is evolved to construct the high‐voltage stable zirconium‐based halide superionic conductors (Li2.5ZrCl5F0.5O0.5, LZCFO). Benefiting from the thermodynamic/kinetic high‐voltage stability of F‐containing SE and the disordered localized structure introduced by O2−, LZCFO displays a practical electrochemical limit of 4.87 V versus Li/Li+ and an ionic conductivity of 1.17 mS cm−1 at 30 °C. With LZCFO and NCM955, the all‐solid‐state lithium battery exhibits a high discharge capacity of 207.1 mAh g−1 at 0.1C and a capacity retention of 81.2% after 500 cycles at 0.5C. The interfacial characterization further demonstrates the formation of the F‐rich cathode–electrolyte interphase (CEI), which inhibits side reactions between the cathode and the SE and boosts excellent cycling stability. This work affords fresh insights on the engineering of SEs with high‐voltage stability, high ionic conductivity, and stable CEI in all‐solid‐state lithium batteries.
A Dual Strategy to Prepare CsPbBr3@glass with a High PLQY and Ultrastability: Combining Controllable Crystallization and Surface Modification
Authors: Zhu Wenying , Cheng Shun , Mei Eenrou , He Ye , Yang Jiapeng , Liu Ruowang , Liang Xiaojuan , Xiang Weidong 
Published: August 2024

AbstractAll‐inorganic perovskite quantum dots (PQDs) are widely applied in photoelectronics because of their high luminous efficiency. However, PQDs have poor stability, which hinders their practical applications. In this study, controllable crystallization of PQDs is achieved by adding Al2O3 to alter the glass network. Next, Na2CO3 (aq) washing‐heating treatment is used to improve the protective mechanism. Owing to this dual strategy, the prepared CsPbBr3@glass exhibits a high photoluminescence quantum yield (PLQY > 95%) and excellent stability. In a 1000 h accelerated aging experiment, the luminous intensity remains above 96% of the initial intensity. The luminescence intensity shows almost no change after soaking in water for 20 weeks. Finally, the CsPbBr3@CsPbBr1I2@PET light‐conversion film is prepared by the sandwich method. Its color gamut covers 138% of the NTSC 1953 and 102% of the Rec. 2020. This CsPbBr3@glass with a high PLQY and ultrastability will broaden the scope of perovskite materials in displays.
In Situ Construction of Fuzzy Sea‐Urchin ZnIn2S4/W18O49: Leveraging Interfacial Z‐Scheme Redox Sites toward Cooperative Electron–Hole Utilization in Photocatalysis
Authors: Ling Grayson Zhi Sheng , Kok Steven Hao Wan , Zhang Peipei , Chiah Zi‐Jing , Tan Lling‐Lling , Chen Binghui , Ong Wee‐Jun 
Published: August 2024

AbstractDespite the significant milestones in the half‐reduction process of photocatalysis, challenges remain in fully utilizing electron–hole pairs in the simultaneous redox reactions. Herein, a Z‐scheme ZnIn2S4/W18O49 (ZW) hybrid with complementary band edge potential is in situ constructed. The resultant fuzzy 1D‐assembled sea‐urchin photocatalyst demonstrates an optimal H2 and benzaldehyde yield of 122 and 106 µmol h−1 under λ > 420 nm light irradiation. This sacrificial‐agent‐free system entails solar‐to‐hydrogen (STH) and apparent quantum efficiency (AQE) values of 0.466% and 2.48% (420 nm), respectively, surpassing most of the recently reported photocatalytic systems without the aid of noble metal cocatalysts. The outstanding performance is mainly attributed to the synergistic formation of intimate Z‐scheme heterojunction and the induction of localized surface plasmon resonances. Comprehensive characterization studies prove the direct injection of energetic hot electrons to promote the number of long‐lived active electrons. Besides, electron paramagnetic resonance and scavenger tests clarify the complicated mechanistic puzzle of the dual‐redox reaction, where benzaldehyde is formed dominantly via O─H activation followed by C─H cleavage of benzyl alcohol over ZW hybrid. Lastly, the universal use of the ZnIn2S4/W18O49 composites is testified in various dual‐redox systems. This study offers a novel outlook for designing dual‐functioning heterojunctions toward a feasible photoredox application.
Composition Modulation‐Mediated Band Alignment Engineering from Type I to Type III in 2D vdW Heterostructures
Authors: Guo Dingli , Fu Qiang , Zhang Guitao , Cui Yueying , Liu Kaiyang , Zhang Xinlei , Yu Yali , Zhao Weiwei , Zheng Ting , Long Haoran , Zeng Peiyu , Han Xu , Zhou Jun , Xin Kaiyao , Gu Tiancheng , Wang Wenhui , Zhang Qi , Hu Zhenliang , Zhang Jialin , Chen Qian , Wei Zhongming , Zhao Bei , Lu Junpeng , Ni Zhenhua 
Published: August 2024

AbstractBand alignment engineering is crucial for facilitating charge separation and transfer in optoelectronic devices, which ultimately dictates the behavior of Van der Waals heterostructures (vdWH)‐based photodetectors and light emitting diode (LEDs). However, the impact of the band offset in vdWHs on important figures of merit in optoelectronic devices has not yet been systematically analyzed. Herein, the regulation of band alignment in WSe2/Bi2Te3‐xSex vdWHs (0 ≤ x ≤ 3) is demonstrated through the implementation of chemical vapor deposition (CVD). A combination of experimental and theoretical results proved that the synthesized vdWHs can be gradually tuned from Type I (WSe2/Bi2Te3) to Type III (WSe2/Bi2Se3). As the band alignment changes from Type I to Type III, a remarkable responsivity of 58.12 A W−1 and detectivity of 2.91×1012 Jones (in Type I) decrease in the vdWHs‐based photodetector, and the ultrafast photoresponse time is 3.2 µs (in Type III). Additionally, Type III vdWH‐based LEDs exhibit the highest luminance and electroluminescence (EL) external quantum efficiencies (EQE) among p‐n diodes based on Transition Metal Dichalcogenides (TMDs) at room temperature, which is attributed to band alignment‐induced distinct interfacial charge injection. This work serves as a valuable reference for the application and expansion of fundamental band alignment principles in the design and fabrication of future optoelectronic devices.
Self‐Anchored Van‐Der‐Waals Stacking Growth of Transition‐Metal Dichalcogenide Nanoplates
Authors: Jiang Dingding , Tang Ya‐Nan , Wang Di , Xu Xiangpeng , Sun Jiang , Ma Rong , Li Wenhao , Han Zhiya , Liu Yunqi , Wei Dacheng 
Published: August 2024

AbstractTransition‐metal dichalcogenide (TMDs) nanoplates exhibit unique properties different from their monolayer counterparts. Controllable nucleation and growth are prerequisite and highly desirable for their practical applications. Here, a self‐anchored van‐der‐Waals stacking growth method is developed, by which the substrate pit induced by precursor etching anchors the source material, impedes the lateral spreading of source droplets and facilitates the in situ stacking growth of high‐quality TMD nanoplates with a thickness of tens to hundreds of nanometers at well‐defined locations. As such, an array of TMD nanoplates with controlled lateral dimensions are produced and applied in arrayed photodetectors. This study solves the problem of controllable preparation of TMD nanoplates, holding promise for applications in electronics and optoelectronics.
Toward Controlled Fluidized Bed – Chemical Vapor Deposition of Boron Nitride: Thermochemical Analysis and Microstructural Investigations
Authors: Da Calva Mouillevois Thomas , Rivière Clément , Plaisantin Hervé , Roger Jérôme , Hungria Teresa , Chollon Georges , Bertrand Nathalie 
Published: August 2024

AbstractThis study examines the optimization and characterization of stoichiometric and carbon‐free boron nitride interphase coatings using triethylamine borane complex as a precursor in the Fluidized Bed Chemical Vapor Deposition process. It highlights the importance of optimizing chemical vapor deposition parameters to control coating formation, limit carbon contamination, and assess the feasibility of stoichiometric boron nitride from triethylamine borane complex coatings. The study investigates the thermal decomposition of triethylamine borane complex and its effect on carbon contamination through theoretical thermodynamic calculations, corroborated by Fourier‐transform infrared spectroscopy. Analysis shows a consistent, uniform microstructure. Auger electron spectroscopy and X‐ray photoelectron spectroscopy confirm the presence of boron, nitrogen, carbon, and oxygen, with negligible carbon inclusions. Transmission electron microscopy and electron energy loss spectroscopy reveal a low‐crystalline, isotropic structure. Carbon‐rich areas in boron nitride coatings indicate intricate chemical interactions during deposition, while disordered structures highlight the need to understand the effects of structural variations. Despite using a high‐carbon precursor, boron nitride coatings are remarkably stoichiometric with low carbon and oxygen contamination, demonstrating the benefits of non‐chlorinated precursors.
Low‐Temperature Poly‐Si Thin‐Film Transistor with High‐k ZrAlOx Gate Insulator with SiO2 Blocking Layer
Authors: Kim Yuna , Jung Byunglib , Islam Md Mobaidul , Kim Byeonggwan , Jang Jin 
Published: August 2024

AbstractLow‐power electronic devices are of increasing interest with high‐k gate insulators (GI). Herein, the performance and stability of low‐temperature poly‐Si (LTPS) thin‐film transistors (TFTs) are investigated with two different GIs: spray pyrolyzed zirconiumaluminum oxide (ZAO) directly deposited on poly‐Si, and SiO2/ZAO stack GI. The LTPS TFT with SiO2/ZAO stack GI exhibits hysteresis free characteristics with a threshold voltage of −0.2 V, field‐effect mobility of 114.4 cm2 V−1 s−1, subthreshold swing of 0.10 V dec−1, and high on/off current ratio of 7.3 × 108, at a gate voltage sweeping ±6 V. The TFT exhibits very stable operation under negative bias temperature stress. The X‐ray photoelectron spectroscopy and high‐resolution transmission electron microscopy analyses demonstrate that the diffusion of Zr and Al into poly‐Si deteriorates device performance with ZAO only GI. A thin SiO2 on LTPS blocks the diffusion of Zr and Al, resulting the high‐performance and stable p‐type LTPS TFT with a high‐k SiO2/ZAO stack GI. Finally, a 7‐stage ring oscillator using LTPS TFTs with SiO2/ZAO stack GI is demonstrated, exhibiting an oscillation frequency of 7.49 MHz and a propagation delay of 9.54 ns at a supply voltage of 6 V, indicating its suitability for low‐power consumption TFT electronics and displays.
Enhancing separation of Y(III) from Sr(II) using tributyl phosphate in a novel deep eutectic solvent media
Authors: Zhao Qi , Wu Fei , Shih Amelie Andrea , Fung Chu Kin , Gao Pengyuan , Liu Mengxian 
Published: August 2024

AbstractA novel solvent extraction system was developed to separate Y3+ from Sr2+, where tributyl phosphate was chosen as an extractant and an organic solvent was a hydrophobic deep eutectic solvent (DES) consisting of oleic acid (OA) and 1‐butyl‐3‐methylimidazolium chloride ([BMIM]Cl). The extraction experiment demonstrated that the extraction system using OA‐[BMIM]Cl DES as an organic solvent exhibited great advantages of fast extraction and excellent selectivity for Y3+ (Y/Sr separation factor >500), which are hardly achieved in the extraction systems using conventional molecular solvent, for example, n‐heptane. Density functional theory calculations also confirmed that the Y/Sr separation is more thermodynamically favorable in OA‐[BMIM]Cl DES as an organic solvent compared to n‐heptane. An extraction process comprising two‐stage extraction, one‐stage scrubbing, and one‐stage stripping was proposed, achieving 95.06% of Y3+ selectively separated from a simulated solution and Y purity of 98.55% in the final product.
Atomically dispersed magnesium with unusual catalytic activity for transesterification reaction
Authors: Shao Xiang‐Bin , Liu Sai , Xing Zhi‐Wei , Tang Jia‐Xin , Li Pan , Liu Chang , Chi Run‐Ze , Tan Peng , Sun Lin‐Bing 
Published: August 2024

AbstractMg and its related solid base catalysts have always been thought of with weak or medium basicity. Herein, we present the synthesis of Mg single atom catalyst (Mg1/NPC) with strong basicity by tuning its coordination environment, which shows unusual activity in strong‐base‐catalyzed transesterification reaction. Mg1/NPC were obtained through impregnation‐pyrolysis method, results manifest Mg single atoms are embedded in nitrogen doped carbon in penta‐coordination (Mg‐C3N2) which endows Mg single atoms with strong basicity and is in contrast to traditional alkaline‐earth metal oxides. The novel Mg1/NPC exhibits excellent activity (40.2%) and stability in transesterification of methanol and ethylene carbonate to produce dimethyl carbonate (DMC), outperforming all state‐of‐the‐art Mg‐based solid base catalysts thus far reported as well as Ca, Na, and K‐based catalysts with superbasicity (2.5%–39.2%). This work might pave the way for the advancement of novel solid base catalysts with extraordinary sources of basicity for multifarious applications.