bluuebunny/crossref_metadata_2025_split huggingface dataset:
Crosscultural comparison of color terms and preference of persimmon‐dyed fabric, Galchon
Authors: Yi Eunjou , Shamey Renzo 
Published: January 2015

AbstractThis crosscultural study was aimed at correlating color emotions and preference for persimmon‐dyed cotton fabrics known as Galchon. Cotton fabrics were dyed with persimmon powder, in a range of shades, and in some cases were also iron mordanted. Textile and fashion students from Jeju National University in Korea and North Carolina State University (NCSU) in USA participated in the visual assessment of dyed samples and were asked to scale their visual experience and state their emotion and preference for the terms “Bright,” “Heavy,” “Soft,” “Strong,” “Deep,” and “Like.” Korean observers used “Strong” for iron‐mordanted Galchon, and American observers did not associate “Bright” or “Deep” with weakly dyed fabrics. In addition to the subjective terms described, the color preference for samples was quantified using their CIE colorimetric attributes. For Korean observers, the results indicate a correlation between L* and “Bright,” whereas for Americans a stronger correlation was obtained against “Soft.” American observers' results also show a relationship between C* and the term “Warm,” especially for dyeings of Galchon at high concentrations. It was also found that iron mordanting affected responses from both groups but only influenced the color preference of Korean observers. © 2015 Wiley Periodicals, Inc. Col Res Appl, 40, 592–604, 2015
Euler angles and crystal symmetry
Authors: Nolze Gert 
Published: February 2015

For the description of (single) crystal orientations, e.g. as measured by electron backscatter diffraction (EBSD) & X‐ray diffraction (XRD), Euler angles are still generally used to import and export data. However, because of the lack of standard definitions for the unit cell reference settings and specimen axes, several transformation descriptions exist which produce different sets of Euler angles for the same orientation. There is also no recommended region within the minimal Euler orientation space into which orientations should be placed. This is the reason why different sets of Euler angles for the same orientation are generated by the available software packages for indexing EBSD patterns. These issues are reviewed and addressed.The influence of crystal symmetry in form of chiral (enantiomorphic) groups is discussed, as well as how multiple, but symmetry‐equivalent sets of Euler angles can be reduced in order to deliver a unique orientation description. The Euler coloring algorithms applied to EBSD map data is critically discussed. The specific case of cubic symmetry, especially the effect of the three‐fold rotation on the Euler space is investigated in more detail for the highest‐symmetric chiral group 432. Recommendations for standard settings of the unit cell to orthogonal coordinate system transformation are given which exploit inherent symmetry.
An electrolytic capacitor‐less LED driver with interleaving flyback topology
Authors: Zhang Taizhi , Qian Qinsong , Xu Shen , Lu Shengli , Sun Weifeng 
Published: February 2015

SummaryHere, we propose a single‐stage alternating current/direct current electrolytic capacitor‐less light‐emitting diode (LED) driver, which applies interleaving flyback topology to reduce the peak‐to‐average ratio of LED driving current. With this approach, the peak current through LEDs is reduced, so the lifetime requirement of LEDs can be satisfied for an electrolytic capacitor‐less LED driver. A new transformer with two interleaving auxiliary windings is applied to this driver. Based on this approach, compared with other electrolytic capacitor‐less LED drivers, an important advantage of this driver is that it can be easily created, without additional control circuits. We will explain the operation principle and control strategy of the proposed driver in detail and will use experimental results taken from a 24‐V 350‐mA prototype to demonstrate its performance. Copyright © 2015 John Wiley & Sons, Ltd.
Quercetin Induces Antiproliferative Activity Against Human Hepatocellular Carcinoma (HepG2) Cells by Suppressing Specificity Protein 1 (Sp1)
Authors: Lee Ra Ham , Cho Jin Hyoung , Jeon Young‐Joo , Bang Woong , Cho Jung‐Jae , Choi Nag‐Jin , Seo Kang Seok , Shim Jung‐Hyun , Chae Jung‐Il 
Published: January 2015

ABSTRACT

Preclinical Research

Quercetin, found in red onions and red apple skin can induce apoptosis insome malignant cells. However, the apoptotic effect of quercetin in hepatocellular carcinoma HepG2 cells via regulation of specificity protein 1 (Sp1) has not been studied. Here, we demonstrated that quercetin decreased cell growth and induce apoptosis in HepG2 cells via suppression of Sp1 using 3‐(4,5‐dimethyl‐2‐yl)‐5‐(3‐carboxymethoxyphenyl)‐2‐(4‐sulfophenyl)‐2H‐tetrazolium, inner salt (MTS) assay, 4′,6‐diamidino‐2‐phenylindole (DAPI) staining, Annexin V, and Western blot analysis, an effect that was dose‐ and time‐dependent manner. Treatment of HepG2 cells with quercetin reduced cell growth and induced apoptosis, followed by regulation of Sp1 and Sp1 regulatory protein. Taken together, the results suggest that quercetin can induce apoptotic cell death by regulating cell cycle and suppressing antiapoptotic proteins. Therefore, quercetin may be useful for cancer prevention. Drug Dev Res 76 : 9–16, 2015
The Role of Potassium Channels in the Vasodilatation Induced by Resveratrol and Naringenin in Isolated Human Umbilical Vein
Authors: Protić Dragana , Radunović Nebojša , Spremović‐Rađenović Svetlana , Živanović Vladimir , Heinle Helmut , Petrović Aleksandar , Gojković‐Bukarica Ljiljana 
Published: January 2015

Abstract

Preclinical Research

Potassium (K+) channels have a key role in the maintenance of smooth muscle tone; a variety of agonists can modify the tone by altering K+‐channel activity. The aim of this study was assess the effects of the phenols, resveratrol, and naringenin on K+‐channels of the vascular smooth muscle. Segments of human umbilical vein (HUV) without endothelium were precontracted using serotonin (100 μM) or 100 mM K+ to derive cumulative concentration‐response curves using increasing concentrations of resveratrol or naringenin. K+‐channel inhibitors were added in the bath before resveratrol (1–100 μM) or naringenin (0.01–1 mM) in assess the role of K+‐channels in their effects on HUV precontracted by serotonin. 4‐Aminopiridine (4‐AP; 1 mM), a nonselective blocker of voltage‐dependent, tetraethylammonium (TEA; 1 mM) and barium chloride (1 mM), a nonselective blocker of Ca2+ ‐dependent and inward rectifier K+‐channels (respectively) induced significant shifts to the right (P < 0.05) of resveratrol. concentration‐response curves. The effect of naringenin was antagonized by 4‐AP (1 mM). 4‐AP‐, TEA‐, and barium chloride‐sensitive K+‐channels are probably involved in the resveratrol vasodilatatory effect, while naringenin seems to affect 4‐AP‐sensitive K+‐channels. However, other mechanisms of vasodilation induced by polyphenols could not be excluded. Drug Dev Res 76 : 17–23, 2015
Thalidomide Inhibits Adhesion Molecules in Experimental Acute Pancreatitis‐Associated Lung Injury
Authors: Lv Peng , Li Hong‐Yun , Ji Shu‐Sheng , Li Wen , Fan Li‐Juan 
Published: January 2015

ABSTRACT

Preclinical Research

The study evaluated the effect of thalidomide on adhesion molecule expression in acute pancreatitis‐associated lung injury in rats. Acute pancreatitis was induced in rats by retrograde infusion of 5% sodium taurocholate into the bile‐pancreatic duct, and thalidomide (100 mg/kg) was given daily by intragastric route for 8 days before this treatment. Serum lipase (LPS), protein levels in bronchoalveolar lavage fluid (BALF), superoxide dismutase (SOD), glutathione peroxidase (GSHpx), and malondialdehyde (MDA) levels in lung were measured. Compared with the acute pancreatitis‐ group, lung histopathology, serum LPS, protein levels in BALF, SOD, GSHpx, and MDA levels, and the expression levels of intercellular adhesion molecule‐1 and E‐selectin mRNA and protein in rats given thalidomide were improved (P < 0.01). Thus, thalidomide may reduce the expression of adhesion molecules via inhibition of oxidative stress to alleviate acute pancreatitis‐associated lung injury in a rat model. Drug Dev Res 76 : 24–30, 2015
5‐HT2B Receptor Antagonists Reduce Nerve Injury‐Induced Tactile Allodynia and Expression of 5‐HT2B Receptors
Authors: Pineda‐Farias Jorge B. , Velázquez‐Lagunas Isabel , Barragán‐Iglesias Paulino , Cervantes‐Durán Claudia , Granados‐Soto Vinicio 
Published: January 2015

ABSTRACT

Preclinical Research

This work was performed to assess the effects of intrathecal serotonin 2B (5‐HT2B) receptor antagonists in rats with neuropathic pain. With RS‐127445, its effect was also determined on 5‐HT2B receptor expression. Neuropathic pain was induced by L5/L6 spinal nerve ligation. Western blotting was used to determine 5‐HT2B receptor expression. Dose‐response curves with the 5‐HT2B receptor antagonists 2‐amino‐4‐(4‐fluoronaphth‐1‐yl)‐6‐isopropylpyridine (RS‐127445, 1–100 nmol) and 1‐[(2‐chloro‐3,4‐dimethoxyphenyl)methyl]‐2,3,4,9‐tetrahydro‐6‐methyl‐1H‐pyrido[3,4‐b]indole hydrochloride (LY‐266097, 1–100 nmol) were performed in rats. Tactile allodynia of the left hind paw (ipsilateral) was assessed for 8 h after compound administration. Intrathecal injection of the 5‐HT2B receptor antagonists RS‐127445 and LY‐266097 diminished spinal nerve ligation‐induced allodynia. In contrast, intrathecal injection of the 5‐HT2 receptor agonist (±)‐2,5‐dimethoxy‐4‐iodoamphetamine hydrochloride (DOI, 10 nmol) did not modify tactile allodynia induced by nerve ligation. L5/L6 nerve ligation increased expression of the 5‐HT2B receptors in the ipsilateral, but not contralateral, dorsal root ganglia. Furthermore, nerve injury also enhanced 5‐HT2B receptor expression in the ipsilateral dorsal part of the spinal cord. Intrathecal treatment with RS‐127445 (100 nmol) diminished spinal nerve injury‐induced increased expression of 5‐HT2B receptors in dorsal root ganglia and spinal cord. Our results imply that spinal 5‐HT2B receptors are present on sites related to nociception and participate in neuropathic pain. © 2014 Wiley Periodicals, Inc Drug Dev Res 76 : 31–39, 2015
Antioxidant Activities of Caralluma tuberculata on Streptozotocin‐Induced Diabetic Rats
Authors: Poodineh Jafar , Khazaei Feizabad Abdurrashid , Nakhaee Alireza 
Published: January 2015

Abstract

Preclinical Research

The aim of this study was to elucidate the antioxidant effects of Caralluma tuberculata (C. tuberculata) in streptozotocin (STZ)‐induced diabetic rats. Diabetes was induced in male Wistar rats with an intraperitoneal injection of STZ at dose of 60 mg/kg body weight. Three days after diabetes induction, powdered aerial part of plant at doses of 100 and 200 mg/kg body weight were gavaged orally for a period of 45 days. The diabetes significantly decreased the activities of superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase, and level of total thiol in liver, kidney, and heart of animals (P < 0.05). In contrast, a significant increase in the levels of protein carbonyl was observed in diabetic rats compared with control animals (P < 0.05). Oral treatment of diabetic rats with C. tuberculata showed ameliorative effects on blood glucose and markers of oxidative stress in a dose‐dependent manner. Altered levels of all oxidative stress parameters in tissues of diabetic rats reverted back to those normal animals after the treatment with dose of 200  mg/kg /day of plant materials. It seems that the appropriate dose of C. tuberculata has both antihyperglycemic and antioxidant activities in STZ‐induced diabetic rats. Therefore, it can have preventive properties on oxidative stress‐induced diabetic complications. Drug Dev Res 76 : 40–47, 2015
Dalbergia odorifera Extract Ameliorates UVB‐Induced Wrinkle Formation by Modulating Expression of Extracellular Matrix Proteins
Authors: Ham Sun Ah , Kang Eun Sil , Yoo Taesik , Lim Hyun Ho , Lee Won Jin , Hwang Jung Seok , Paek Kyung Shin , Seo Han Geuk 
Published: January 2015

Abstract

Preclinical Research

Emerging evidence suggests that Dalbergia odorifera T. Chen (Leguminosae), an indigenous medicinal herb, has therapeutic potential. This study examined the antiwrinkle effects of ethanol extracts of D. odorifera in UVB‐irradiated human skin cells. Ethanol extracts of D. odorifera and thier constituents, dalbergin and sativanone, induced expression of collagen type I and transforming growth factor (TGF)‐β1 in human dermal fibroblasts. In HR‐1 hairless mice exposed to UVB, the ethanol extract reduced wrinkle formation and skin thickness. This inhibitory effect of ethanol extract was associated with the restoration of collagen type I, TGF‐β1, and elastin to levels approaching those in skin tissues not exposed to UVB, which was accompanied by the reduction of matrix metalloproteinase‐2 and upregulation of tissue inhibitors of metalloproteinase (TIMP)‐2 and TIMP‐3 in skin tissue exposed to UVB. These results suggest that the ethanol extracts prevent some effects of photoaging and maintain skin integrity by regulating the degradation of the extracellular matrix proteins. © 2015 Wiley Periodicals, Inc. Drug Dev Res 76 : 48–56, 2015
Cross‐fostering differentially affects ADHD‐related behaviors in spontaneously hypertensive rats
Authors: Gauthier Angela C. , DeAngeli Nicole E. , Bucci David J. 
Published: February 2015

ABSTRACTAlthough both genetic and non‐genetic factors are known to contribute to the occurrence of Attention‐Deficit Hyperactivity/Disorder (ADHD), little is known about how they impact specific symptoms. We used a cross‐fostering approach with an established animal model of ADHD, the Spontaneously Hypertensive Rat strain (SHR), to test the influence of genotype and maternal behavior on ADHD‐related behaviors. SHRs and their normo‐active genetic relative, Wistar Kyoto rats (WKY), were cross‐fostered to an unfamiliar dam of either the same or different strain. Behavioral testing took place when the rats reached adulthood. Locomotor hyperactivity was completely dependent on the strain of the offspring. In contrast, social behavior was primarily determined by the strain of the mother, while attentional orienting behavior was influenced by both the strain of the offspring and the strain of the dam. Anxiety‐related behavior was influenced by an interaction between offspring and dam strain. © 2015 Wiley Periodicals, Inc. Dev Psychobiol 57: 226–236, 2015.
Gender‐Biased Breastfeeding in Egypt: Examining the Fertility Preference Hypotheses of Jayachandran and Kuziemko (2011)
Authors: Chakravarty Abhishek 
Published: February 2015

SummaryJayachandran and Kuziemko (Why do mothers breastfeed girls less than boys? Evidence and implications for child health in India. Quarterly Journal of Economics 2011; 126(3): 1485–1538) develop and empirically validate a theory showing son preference in India generates ‘passive’ parental bias against girls in breastfeeding due to gender‐differentiated birth spacing and fertility stopping. I scientifically replicate their empirical exercises to test the validity of the theory in Egypt, where there is also high prevailing son preference, but little research on its implications for child health investments. I additionally examine whether using the exclusive breastfeeding rate as an alternative outcome yields supportive evidence for the theory. I find the theory is strongly supported by empirical results from Egyptian data, bolstering its policy relevance for developing countries besides India. Copyright © 2015 John Wiley & Sons, Ltd.
Determination of α‐tocopherol by reversed‐phase HPLC in feed and animal‐derived foods without saponification
Authors: Claeys Erik , Vossen Els , De Smet Stefaan 
Published: February 2015

AbstractBACKGROUNDThe analysis of α‐tocopherol in feed and animal‐derived foods usually involves a saponification step. However, since saponification often leads to losses of α‐tocopherol, a method for the determination of α‐tocopherol in feed and in animal‐derived foods was developed without a saponification step.RESULTSIn this method, α‐tocopherol is extracted with hot ethanol and the co‐extracted fat is removed by centrifugation. Removal of the fat fraction is made possible by the addition of water, to achieve an ethanol:water ratio of 40:7, followed by cooling on ice before centrifugation. This procedure allows removal of the fat fraction, while α‐tocopherol is retained. Matrices differing in gross composition and α‐tocopherol content were analyzed: fresh pork, cooked ham, subcutaneous fat, liver, egg yolk, milk and a compound pig feed. Higher α‐tocopherol concentrations were found for this novel method compared to a conventional method with saponification, particularly for subcutaneous fat (P < 0.05). Recoveries were higher (P < 0.05) for the novel method (82–103%), compared to the saponification method (66–90%; for subcutaneous fat < 25%).CONCLUSIONDetermining α‐tocopherol in feed and animal‐derived foods using pure ethanol without saponification results in higher extraction yields and recoveries compared to the saponification method. © 2015 Society of Chemical Industry
Comparative analysis of resistance gene analogues encoding NBS‐LRR domains in cotton
Authors: Khan Abdul Manan , Khan Asif Ali , Azhar Muhammad Tehseen , Amrao Luqman , Cheema Hafiza Masooma Naseer 
Published: February 2015

AbstractBACKGROUNDPlant production is severely affected by biotic and abiotic stresses R‐genes exhibit resistance against a range of diseases and pathogens in plants. The nucleotide binding site and leucine rich repeat (NBS‐LRR) class of R‐genes is the most comprehensively studied in terms of sequence evolution and genome distribution. The differential response for resistance against biotic and abiotic stress has been observed in cultivated and wild relatives of the genus Gossypium.RESULTSEfforts have been made to address the recent evolution of NBS‐LRR sequences within Gossypium hirsutum and resistance gene analogue (RGA) sequences derived from G. arboreum and G. raimondii. The % identity and phylogenetic analysis of NBS‐LRR‐encoded RGAs from tetraploid New World cotton and its diploid ancestors G. raimondii and G. arboreum suggest that the evolution of NBS‐LRR‐encoding sequences in G. hirsutum occurred by gradual accumulation of mutants that led to positive selection and a slow rate of divergence within distinct R‐gene families.CONCLUSIONThe allotetraploid genome of cotton, after separating from its diploid parents, experienced polyploidisation, natural and artificial selection, hybrid necrosis, duplication and recombination which became the reason to shed off and evolve new genes for its survival. These driving forces influenced the development of genomic architecture that make it susceptible to diseases and pathogens as compared to donor parents. © 2015 Society of Chemical Industry
Surgical resection versus transarterial chemoembolization for BCLC stage C hepatocellular carcinoma
Authors: Liu Po‐Hong , Hsia Cheng‐Yuan , Lee Yun‐Hsuan , Hsu Chia‐Yang , Huang Yi‐Hsiang , Su Chien‐Wei , Lee Rheun‐Chuan , Lin Han‐Chieh , Huo Teh‐Ia 
Published: February 2015

BackgroundSorafenib is the only recommended treatment for patients with Barcelona Clinic Liver Cancer (BCLC) stage C hepatocellular carcinoma (HCC). We aimed to compare surgical resection (SR) and transarterial chemoembolization (TACE) for advanced (BCLC stage C) HCC patients.MethodsA total of 264 and 389 advanced HCC patients received SR and TACE, respectively. Among them, 163 matched pairs of patients were identified from each treatment arm by propensity score matching analysis to compare long‐term survival.ResultsOf all patients, the SR group had better liver functional reserve than the TACE group. In the matched propensity model, the baseline characteristics were similar between patients receiving SR and TACE. SR provided significantly better long‐term survival than TACE in all patients and in patients selected in the propensity model (both P < 0.001). In the Cox proportional hazards model, patients receiving TACE had a 2.393‐fold increased risk of mortality compared with patients receiving SR (95% confidence interval: 1.610–3.556, P < 0.001).ConclusionsSR provides significantly better long‐term survival than TACE in patients with BCLC stage C HCC, and should be an integral part in the management of advanced HCC. Multidisciplinary approaches for these patients and further amendment to the BCLC classification scheme are required. J. Surg. Oncol. 2015 111:404–409. © 2015 Wiley Periodicals, Inc.
Prevalence and triage of first contact pelvic floor dysfunction complaints in male patients referred to a Pelvic Care Centre
Authors: Berghmans Bary , Nieman Fred , Leue C. , Weemhoff M. , Breukink S. , van Koeveringe G. 
Published: January 2015

Aims(i) To describe and analyse pelvic floor dysfunction symptoms in men referred to a Pelvic Care Centre (PCC). (ii) To describe the triage process of the same patients based on response to a first‐contact interview.MethodsTriage started with a telephone interview using previously constructed questions, asking for six types of PF complaints during the preceding 6 months. If present, complaint severity was registered on a 0–10 scale. Next, these first‐contact complaints were used to describe patient case mix profiles using cross‐tabular analysis. Later on, at first PCC visit, an intake questionnaire regarding specific PF health problem(s) was filled out. This procedure contributed to a firm baseline characterization of the individual patient profile and a clinically valid allocation to structured, predefined assessment and treatment.ResultsFrom 2005 to 2013 985 first‐time patients (mean age 58.2 years (SD 15.3) have been referred to the PCC. Most frequently mentioned complaints: voiding dysfunctions (73.9%), urinary incontinence (29.5%), sexual problems (16.6%), faecal incontinence (13.9%), constipation (9.6%), and prolapse (0.3%). A first appointment to a single specialist was determined in 805 (81.7%) patients, in 137 (13.9%) consultation of >1 specialist. Data analysis revealed higher‐order interactions between PF complaints, suggesting patient profile complexity and patient population heterogeneity.ConclusionsOne out of seven PCC patients showed multifactorial problems, needing >1 specialist. PF complaints either turned out to stand alone or cluster with others, or even to strengthen, weaken, nullify or inverse relationships. Neurourol. Urodynam. 35:487–491, 2016. © 2015 Wiley Periodicals, Inc.