bluuebunny/crossref_metadata_2025_split huggingface dataset:
The perspectives and barriers for the implementation of CCS in Poland
Authors: Uliasz‐Misiak Barbara , Przybycin Andrzej 
Published: September 2015

AbstractOver 90% of Polish energy comes from burning fossil fuels, i.e., hard coal and lignite, responsible for high greenhouse gas (including CO2) emissions. The need to adapt to international agreements, expected increase of CO2 emissions, limited technological capabilities to reduce emissions, the energy intensity of industry and geological conditions allowing underground storage make carbon capture and storage (CCS) a viable option to reduce CO2 emissions. The implementation of CCS on a commercial scale depends on many factors, including the development of capture technology, transport options, and the geological structure. Its applicability is highly dependent on the regulations and economic, energy, and environmental policy. At the current stage of work, the biggest problems in the implementation of CCS include legal regulations, social acceptance, and cost reduction. The numerous political and economic benefits may balance the costs of CCS technology implementation. The captured CO2 can be used in the exploitation of oil fields and in large‐scale industrial processes. The implementation of CCS can contribute to the introduction of high‐efficient technologies and modernization of the national energy sector. The development of CCS can help to create new jobs, stimulate the development of the Polish economy and contribute to the development of research in this field. © 2015 Society of Chemical Industry and John Wiley & Sons, Ltd
Facile synthesis of a thermally stable imine and benzimidazole functionalized nanoporous polymer (IBFNP) for CO2 capture application
Authors: Muhammad Raeesh , Rekha Pawan , Mohanty Paritosh 
Published: September 2015

AbstractAn imine and benzimidazole functionalized nanoporous polymer (IBFNP) has been synthesized by a single‐step condensation reaction between 3,3´‐diaminobenzidene and terephthaldehyde at 150 °C. The IBFNP‐1 has a moderately high BET specific surface area of 1040 m2/g with pore diameter centered at 1.4 nm and pore volume of 1.46 cm3/g. The IBFNP‐1 could reversibly capture 5.27 mmol/g (23.2 wt%) of CO2 at 273 K and 1 atm, which is among the best reported microporous organic polymers. The good selectivity of CO2 over N2 (65:1) and moderately high isosteric heat of adsorption (33.8 kJ/mol) make this material a good adsorbent for the CO2 capture application.© 2015 Society of Chemical Industry and John Wiley & Sons, Ltd
Development of the brain's structural network efficiency in early adolescence: A longitudinalDTItwin study
Authors: Koenis Marinka M.G. , Brouwer Rachel M. , van den Heuvel Martijn P. , Mandl René C.W. , van Soelen Inge L.C. , Kahn René S. , Boomsma Dorret I. , Hulshoff Pol Hilleke E. 
Published: September 2015

AbstractThe brain is a network and our intelligence depends in part on the efficiency of this network. The network of adolescents differs from that of adults suggesting developmental changes. However, whether the network changes over time at the individual level and, if so, how this relates to intelligence, is unresolved in adolescence. In addition, the influence of genetic factors in the developing network is not known. Therefore, in a longitudinal study of 162 healthy adolescent twins and their siblings (mean age at baseline 9.9 [range 9.0–15.0] years), we mapped local and global structural network efficiency of cerebral fiber pathways (weighted with mean FA and streamline count) and assessed intelligence over a three‐year interval. We find that the efficiency of the brain's structural network is highly heritable (locally up to 74%). FA‐based local and global efficiency increases during early adolescence. Streamline count based local efficiency both increases and decreases, and global efficiency reorganizes to a net decrease. Local FA‐based efficiency was correlated to IQ. Moreover, increases in FA‐based network efficiency (global and local) and decreases in streamline count based local efficiency are related to increases in intellectual functioning. Individual changes in intelligence and local FA‐based efficiency appear to go hand in hand in frontal and temporal areas. More widespread local decreases in streamline count based efficiency (frontal cingulate and occipital) are correlated with increases in intelligence. We conclude that the teenage brain is a network in progress in which individual differences in maturation relate to level of intellectual functioning.Hum Brain Mapp 36:4938–4953, 2015. © 2015 Wiley Periodicals, Inc.
Rapid SERS monitoring of lipid‐peroxidation‐derived protein modifications in cells using photonic crystal fiber sensor
Authors: Gong Tianxun , Zhang Nan , Kong Kien Voon , Goh Douglas , Ying Cui , Auguste Jean‐Louis , Shum Perry Ping , Wei Lei , Humbert Georges , Yong Ken‐Tye , Olivo Malini 
Published: September 2015

We proposed a side channel photonic crystal fiber (SC‐PCF) based Surface enhanced Raman spectroscopy (SERS) platform which is able to accurately monitor lipid peroxidation derived protein modifications in cells. This platform incorporates linoleamide alkyne (LAA), which is oxidized and subsequently modifies proteins in cells with alkyne functional group upon lipid peroxidation. By loading the side channel of SC‐PCF with a mixture of gold nanoparticles and LAA treated cells, and subsequently measuring the interference‐free alkyne Raman peak from these proteins in cells, strong SERS signal was obtained. The platform provides a method for the rapid monitoring of lipid peroxidation derived protein modification in cells.
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The Neuroprotective Role of Insulin Against MPP+‐Induced Parkinson's Disease in Differentiated SH‐SY5Y Cells
Authors: Ramalingam Mahesh , Kim Sung‐Jin 
Published: September 2015

ABSTRACTParkinson's disease (PD) is a common chronic neurodegenerative disorder associated with aging that primarily caused by the death of dopaminergic neurons in the substantia nigra pars compacta (SN). Retinoic acid (RA)‐differentiated human neuroblastoma SH‐SY5Y cells (SH‐SY5Y+RA) have been broadly utilized in studies of mechanisms of the pathogenesis underlying 1‐Methyl‐4‐phenyl pyridinium (MPP+)‐induced PD models. Here, we investigated the neuroprotective mechanisms of insulin on MPP+‐induced neurotoxicity on SH‐SY5Y+RA cells. Recent studies suggest that insulin has a protective effect against oxidative stress but not been elucidated for PD. In this study, pretreatment of insulin prevented the cell death in a dose dependent manner and lowered nitric oxide (NO) release, reactive oxygen species (ROS), and calcium ion (Ca2+) influx induced by MPP+. Insulin also elevated tyrosine hydroxylase (TH) and insulin signaling pathways in dopaminergic neuron through activating PI3K/Akt/GSK‐3 survival pathways which in turn inhibits MPP+‐induced iNOS and ERK activation, and Bax to Bcl‐2 ratio. These results suggest that insulin has a protective effect on MPP+‐neurotoxicity in SH‐SY5Y+RA cells. J. Cell. Biochem. 117: 917–926, 2016. © 2015 Wiley Periodicals, Inc.
Cost analysis of vestibular schwannoma screening with contrast-enhanced magnetic resonance imaging in patients with asymmetrical hearing loss
Authors: Pan P , Huang J , Morioka C , Hathout G , El-Saden S M 
Published: September 2015

AbstractBackground:Vestibular schwannomas are a rare cause of asymmetrical hearing loss, and routine screening with magnetic resonance imaging can be costly. This paper reports results on vestibular schwannoma screening at our institution and compares the cost of screening to a utility of hearing benefit.Method:All screening examinations with magnetic resonance imaging performed for asymmetrical hearing loss between 2006 and 2011 were retrospectively reviewed. The cost per new vestibular schwannoma diagnosis was calculated. The cost per patient for those who benefitted from intervention was estimated based on rates of hearing preservation reported in the literature.Results:Forty-five (4.3 per cent) of 1050 screening examinations with magnetic resonance imaging performed for asymmetrical hearing loss were positive for vestibular schwannoma, and the cost per new diagnosis was $11 436. The estimated screening cost per patient for those who benefitted from surgery or radiation was $147 030, while US federal compensation for unilateral hearing loss was $44 888.Conclusion:Although we achieved a lower screening cost per new diagnosis than reported in the current literature, there remains disparity between the screening cost per benefitted patient and the ‘benefit’ of hearing.
Unique and accurate soil parameter identification for air-cushioned robotic vehicles
Authors: Xu Shuo , Gu Yinan , Sun Jing , Tu Dawei 
Published: September 2015

SUMMARYOn-line identification of soil parameters is a pre-condition of operating performance optimization and control for unmanned ground vehicles (UGV). Inverse calculation from measured vehicular operating parameters is a prevalent methodology. However, it inherently suffers from a multiple-solution problem caused by the coupling of soil parameters in terramechanics equations and an accuracy problem caused by the influences of state noise and measurement noise. These problems in tractive-force-related soil parameters identification were addressed here for air-cushioned vehicles (ACV) by taking advantage of their additional degree of control freedom in vertical force. To be specific, a g-function algorithm was proposed to solve the multiple-solution problem from reproductive tractive force equations; de-noising techniques consisting of mean-effect strategies, sampling points selection and sample rearrangement were employed to solve the accuracy problem. A series of experiments were conducted to evaluate these techniques at different noise levels and in different soil conditions. They got satisfactory results in terms of data utilization ratio, identification accuracy and performance stability. The contribution of the paper lies in inventing a novel algorithm for unique and accurate identification of tractive-force-related soil parameters without making any simplification to the original terramechanics equation and with robustness to variations of noise level and soil condition.
High burden of invasive group A streptococcal disease in the Northern Territory of Australia
Authors: BOYD R. , PATEL M. , CURRIE B. J. , HOLT D. C. , HARRIS T. , KRAUSE V. 
Published: September 2015

SUMMARYAlthough the incidence of invasive group A streptococcal disease in northern Australia is very high, little is known of the regional epidemiology and molecular characteristics. We conducted a case series of Northern Territory residents reported between 2011 and 2013 withStreptococcus pyogenesisolates from a normally sterile site. Of the 128 reported episodes, the incidence was disproportionately high in the Indigenous population at 69·7/100 000 compared to 8·8/100 000 in the non-Indigenous population. Novel to the Northern Territory is the extremely high incidence in haemodialysis patients of 2205·9/100 000 population; and for whom targeted infection control measures could prevent transmission. The incidences in the tropical north and semi-arid Central Australian regions were similar. Case fatality was 8% (10/128) and streptococcal toxic shock syndrome occurred in 14 (11%) episodes. Molecular typing of 82 isolates identified 28emmtypes, of which 63 (77%) were represented by fouremmclusters. Typing confirmed transmission between infant twins. While the diverse range ofemmtypes presents a challenge for effective coverage by vaccine formulations, the limited number ofemmclusters raises optimism should cluster-specific cross-protection prove efficacious. Further studies are required to determine effectiveness of chemoprophylaxis for contacts and to inform public health response.
Halmyris, a settlement and fort near the mouth of the Danube: interim report
Authors: Zahariade Mihail , Phelps Myrna K. 
Published: September 2015

Ancient Halmyris lies in the NW corner of the Dobrudja region in SE Romania. It liesc.2.5 km east of the village of Murighiol on a rocky promontory which is slightly higher than the surrounding marshes. This is at the E end of the Dunavat peninsula (known in antiquity asExtrema Scythiae Minoris: Jord., Get.266) and it is bordered by the Danube delta on the north and east, Razelm lake on the south, and the Tulcea hills on the west (fig. 1). The site was occupied continuously from at least the mid-first millennium B.C. up to the 7th c. A.D. The local environment, flora and fauna were favourable to settlement until as a result of natural causes the Danube became almost inaccessible; from that point on, the settlement became vulnerable to human and other natural events and eventually it became deserted.The site is known today as Bataraia or Cetatea. In the early 20th c. the locals still called it the Genoese stronghold (Geneviz-Kaleh). In antiquity it lay on the bank of the southern arm of the Danube called Peuce (now known as Sfantu Gheorghe). Today the southern arm of the Danube runs 2 km north of the site and it is connected to Lake Murighiol by the Periboina canal. Until 1983 there were two lakes,c.100 andc.200 m from the site, modern relics of the ancient course of the river. To the east lie the Dunavat hills and to the south is Dealul Cetatea (“fort hill”) (fig. 2).
The Via Egnatia (Albania) Project and the bridge at Topçias
Authors: Amore Maria Grazia , Bejko Lorenc , Cerova Ylli , Gjipali Ilir 
Published: September 2015

The Via Egnatia has attracted limited attention over the last half-century. The ancient road, crossing Albania between Durrës (Dyrrachium) and Qafe Thane, was one of the major thoroughfares of antiquity, and it remained in use until modern times. This brief report describes the work of the new Albanian Rescue Archaeology Unit, working in collaboration with the Institute of Archaeology of Albania, in an attempt to document parts of the road which may be threatened by infrastructure development.The survey was organised during April and May 2000 and involved both systematically walking the line followed by the Via Egnatia and visiting sites of different periods that developed along it. During the first season, our survey concentrated upon the area between Bradashesh (identified as themutatio Ad Quintumof the Roman itineraries), near Elbasan, and Qukës (mutatio In Tabernasof theItinerarium Burdigalense, orTrès Tabernaeof the Antonine Itinerary) (fig. 1).
The role of mRNA and protein stability in the function of coupled positive and negative feedback systems in eukaryotic cells
Authors: Moss Bendtsen Kristian , Jensen Mogens H. , Krishna Sandeep , Semsey Szabolcs 
Published: September 2015

AbstractOscillators and switches are important elements of regulation in biological systems. These are composed of coupling negative feedback loops, which cause oscillations when delayed and positive feedback loops, which lead to memory formation. Here, we examine the behavior of a coupled feedback system, the Negative Autoregulated Frustrated bistability motif (NAF). This motif is a combination of two previously explored motifs, the frustrated bistability motif (FBM) and the negative auto regulation motif (NAR), which both can produce oscillations. The NAF motif was previously suggested to govern long term memory formation in animals and was used as a synthetic oscillator in bacteria. We build a mathematical model to analyze the dynamics of the NAF motif. We show analytically that the NAF motif requires an asymmetry in the strengths of activation and repression links in order to produce oscillations. We show that the effect of time delays in eukaryotic cells, originating from mRNA export and protein import, are negligible in this system. Based on the reported protein and mRNA half-lives in eukaryotic cells, we find that even though the NAF motif possesses the ability for oscillations, it mostly promotes constant protein expression at the biologically relevant parameter regimes.
Metalloprotease OMA1 Fine-tunes Mitochondrial Bioenergetic Function and Respiratory Supercomplex Stability
Authors: Bohovych Iryna , Fernandez Mario R. , Rahn Jennifer J. , Stackley Krista D. , Bestman Jennifer E. , Anandhan Annadurai , Franco Rodrigo , Claypool Steven M. , Lewis Robert E. , Chan Sherine S. L. , Khalimonchuk Oleh 
Published: September 2015

AbstractMitochondria are involved in key cellular functions including energy production, metabolic homeostasis and apoptosis. Normal mitochondrial function is preserved by several interrelated mechanisms. One mechanism – intramitochondrial quality control (IMQC) – is represented by conserved proteases distributed across mitochondrial compartments. Many aspects and physiological roles of IMQC components remain unclear. Here, we show that the IMQC protease Oma1 is required for the stability of the respiratory supercomplexes and thus balanced and tunable bioenergetic function. Loss of Oma1 activity leads to a specific destabilization of respiratory supercomplexes and consequently to unbalanced respiration and progressive respiratory decline in yeast. Similarly, experiments in cultured Oma1-deficient mouse embryonic fibroblasts link together impeded supercomplex stability and inability to maintain proper respiration under conditions that require maximal bioenergetic output. Finally, transient knockdown of OMA1 in zebrafish leads to impeded bioenergetics and morphological defects of the heart and eyes. Together, our biochemical and genetic studies in yeast, zebrafish and mammalian cells identify a novel and conserved physiological role for Oma1 protease in fine-tuning of respiratory function. We suggest that this unexpected physiological role is important for cellular bioenergetic plasticity and may contribute to Oma1-associated disease phenotypes in humans.
Putting on the brakes: Bacterial impediment of wound healing
Authors: Brothers Kimberly M. , Stella Nicholas A. , Hunt Kristin M. , Romanowski Eric G. , Liu Xinyu , Klarlund Jes K. , Shanks Robert M. Q. 
Published: September 2015

AbstractThe epithelium provides a crucial barrier to infection and its integrity requires efficient wound healing. Bacterial cells and secretomes from a subset of tested species of bacteria inhibited human and porcine corneal epithelial cell migration in vitro and ex vivo. Secretomes from 95% of Serratia marcescens, 71% of Pseudomonas aeruginosa, 29% of Staphylococcus aureus strains and other bacterial species inhibited epithelial cell migration. Migration of human foreskin fibroblasts was also inhibited by S. marcescens secretomes indicating that the effect is not cornea specific. Transposon mutagenesis implicated lipopolysaccharide (LPS) core biosynthetic genes as being required to inhibit corneal epithelial cell migration. LPS depletion of S. marcescens secretomes with polymyxin B agarose rendered secretomes unable to inhibit epithelial cell migration. Purified LPS from S. marcescens, but not from Escherichia coli or S. marcescens strains with mutations in the waaG and waaC genes, inhibited epithelial cell migration in vitro and wound healing ex vivo. Together these data suggest that S. marcescens LPS is sufficient for inhibition of epithelial wound healing. This study presents a novel host-pathogen interaction with implications for infections where bacteria impact wound healing and provides evidence that secreted LPS is a key factor in the inhibitory mechanism.
Criteria for Applying the Lucas-Washburn Law
Authors: Li Kewen , Zhang Danfeng , Bian Huiyuan , Meng Chao , Yang Yanan 
Published: September 2015

AbstractSpontaneous imbibition happens in many natural and chemical engineering processes in which the mean advancing front usually follows Lucas-Washburn’s law. However it has been found that the scaling law does not apply in many cases. There have been few criteria to determine under what conditions the Washburn law works. The effect of gravity on spontaneous imbibition in porous media was investigated both theoretically and experimentally. The mathematical model derived analytically was used to calculate the imbibition rates in porous media with different permeabilities. The results demonstrated that the effect of gravity on spontaneous imbibition was governed by the hydraulic conductivity of the porous media (permeability of the imbibition systems). The criteria for applying the Lucas-Washburn law have been proposed. The effect of gravity becomes more apparent with the increase in permeability or with the decrease in CGR number (the ratio of capillary pressure to gravity forces) and may be ignored when the CGR number is less than a specific value "Equation missing" ≅ 3.0. The effect of gravity on imbibition in porous media can be modeled theoretically. It may not be necessary to conduct spontaneous imbibition experiments horizontally in order to exclude the effect of gravity, as has been done previously.
Living without DAT: Loss and compensation of the dopamine transporter gene in sauropsids (birds and reptiles)
Authors: Lovell P. V. , Kasimi B. , Carleton J. , Velho T. A. , Mello C. V. 
Published: September 2015

AbstractThe dopamine transporter (DAT) is a major regulator of synaptic dopamine (DA) availability. It plays key roles in motor control and motor learning, memory formation and reward-seeking behavior, is a major target of cocaine and methamphetamines and has been assumed to be conserved among vertebrates. We have found, however, that birds, crocodiles and lizards lack the DAT gene. We also found that the unprecedented loss of this important gene is compensated for by the expression of the noradrenaline transporter (NAT) gene and not the serotonin transporter genes, in dopaminergic cells, which explains the peculiar pharmacology of the DA reuptake activity previously noted in bird striatum. This unexpected pattern contrasts with that of ancestral vertebrates (e.g. fish) and mammals, where the NAT gene is selectively expressed in noradrenergic cells. DA circuits in birds/reptiles and mammals thus operate with an analogous reuptake mechanism exerted by different genes, bringing new insights into gene expression regulation in dopaminergic cells and the evolution of a key molecular player in reward and addiction pathways.
Measuring warmth and competence at inter-group, interpersonal and individual levels / Medición de la cordialidad y la competencia en los niveles intergrupal, interindividual e individual
Authors: Aragonés Juan I. , Poggio Lucía , Sevillano Verónica , Pérez-López Raquel , Sánchez-Bernardos María-Luisa 
Published: September 2015

Warmth and competence are universal dimensions of social perception that articulate the perception of other individuals and social groups. However, there are no scales that have systematically been used in psychosocial research. The purpose of this study is to construct two scales, one on warmth and another on competence, which could be used at the inter-group, interpersonal and individual levels. To accomplish this, we performed two studies. In Study I ( N = 578 students and N = 540 general population), we tested the scales at the intergroup level (immigrant groups and Spaniards), the interpersonal level (people close to the participants) and the individual level (the participants themselves). In Study 2 ( N = 184 students), the two scales were tested at an interpersonal level by evaluating 16 public figures. The results of both studies show that both the warmth scale ( kind, pleasant, friendly, warm) and the competence scale ( competent, effective, skilled, intelligent) achieved a high degree of reliability when reflecting the perception of groups, individuals and oneself.