bluuebunny/crossref_metadata_2025_split huggingface dataset:
The possibilities of predicting the individual risk of cervical cancer in women of reproductive age using mathematical modeling
Authors: Klyukina L. A. , Sosnova E. A. , Ishchenko A. A. , Davydov M. M. 
Published: July 2024

Background. Cervical cancer (CC) refers to cancer of visual localization and in women of reproductive age remains one of the most common oncological diseases. The carcinogenesis of CC is caused by the persistence of highly oncogenic types of human papillomavirus (HPV), the level of carcinogenicity of which is the highest based on the criteria of the International Agency for Research on Cancer. However, cervical carcinogenesis does not occur in all cases of persistence of highly oncogenic types of HPV. This, in turn, determines the need for a thorough search, study and analysis of possible cofactors that can lead to neoplastic changes in the cervix.Aim. To develop a model for predicting the individual risk of CC in women of reproductive age, taking into account clinical, anamnestic, laboratory and histological data.Materials and methods. The material for the study was retrospective examination data from 251 patients of reproductive age who were treated at the Center for Gynecology and Reproductive Technologies of the National Medical Research Center “Medical and Rehabilitation Center”, Ministry of Health of Russia in the period 2015–2022. Results. Highly oncogenic HPV types were significantly more common in the group of patients with verified СС who took combined oral contraceptives (COC), compared with patients who did not take COC (p = 0.035). Multifactorial analysis allowed us to determine that long-term use of СОС for a total of more than 7 years is associated with a tendency to increase the risk of developing СС (hazard ratio 1.68; 95 % confidence interval 1.1–2.5; p = 0.010). According to the results of statistical calculation, the values of regression coefficients were obtained and the tendency to increase the risk of developing CC was predicted in the presence of such factors as: HPV type 16 persistence, body mass index, and the duration of COC intake in years.Conclusion. Thus, taking into account all possible risk factors for CC, the negative effect of cofactors, namely increased body mass index and prolonged intake of COC, on the course of HPV as the leading etiological factor of breast cancer, will allow us to identify groups at increased risk of developing CC, form an individual algorithm for monitoring and examination throughout the entire period of taking COC, as well as conduct individual cancer prevention by limiting the duration of taking COC.
Relief Candi Jago sebagai Sumber Inspirasi Penciptaan Karya Seni Batik Lukis dengan Karakter Subkultur Black Metal
Authors: Ahmad Daffa Reyhan , Arimbawa Anak Agung Gde Rai , Sidyawati Lisa 
Published: July 2024

Candi Jago adalah salah satu candi Buddha yang berada di desa Tumpang Kabupaten Malang, terletak pada 22 kilometer arah timur Malang. Nama Candi Jago berasal dari nama ‘Jajaghu’ yang berarti ‘keagungan’, istilah yang digunakan untuk penyebutan tempat suci. Relief yang terdapat pada Candi Jago memiliki arti tersendiri dan memuat banyak pesan moral. Pada era modern ini,kesadaran akan hal tersebut masih terbilang rendah. Pernyataan ini didukungoleh hasil pengamatan dan wawancara yang dilakukan penulis kepada beberapa generasi penerus. Penulis memilih skripsi penciptaan ini bertujuan untuk mendeskripsikan makna relief Candi Jago, mendeskripsikan proses visualisasi ide menjadi karya batik lukis, dan mendeskripsikan hasil, serta gelar karya penciptaan batik lukis yang bersumber dari relief Candi Jago. Pada penciptaan karya ini, penulis menggunakan metode penciptaan dari SP. Gustami. Metode ini mempunyai tiga tahapan, yaitu: (1) eksplorasi; (2) perancangan dan perwujudan; dan (3) penilaian dan evaluasi. Ketiga tahapan ini penulis kembangkan hingga menjadi enam hasil karya batik lukis yang bergaya subkultur Black Metal, karya yang mengandung falsafah hidup, pesan moral dan nilai - nilai budaya. Enam hasil karya tersebut, antara lain Tantri I, Tantri II, Ogal-Agil, Kawah Tambradimuka, Drupadi, dan Arjunawiwaha. Setiap karya yang melibatkan pelestarian relief candi Jago dan berasal dari masyarakat sekaligus penikmat seni batik lukis akan disajikan dalam bentuk pameran.
Transurethral resection of the prostate: one-year experience in a single centre
Authors: Omodu Jack O. , George Abiye F. , Clement Marie-Theres E. 
Published: July 2024

Background: Benign prostatic hyperplasia (BPH) is the most common cause of lower urinary tract symptoms among older males. Transurethral resection of the prostate (TURP) still remains the gold standard in the treatment of benign prostatic hyperplasia. However, its availability is not widespread in most public healthcare facilities across sub-Saharan Africa. This study was designed to describe and share our experience of TURP in a single centre.
Methods: This is a retrospective evaluation of 64 patients who had TURP for bladder outlet obstruction secondary to enlarged prostate. The records of men who had TURP over a period of one year (January 2022-December 2022) were retrieved and reviewed. The pre-operative prostate specific antigen (PSA), pre-operative ultrasound measured size of prostate, resected weight of prostate, duration of surgery, duration of hospital stay, indication for TURP and complications were analysed.
Results: Sixty-four patients had TURP done during the period under review. The age range was 50-90 years (mean 68.33), the pre-operative prostate gland weight was 76.78gm. The mean resected weight was 53.9gm. The pre-operative serum prostate specific antigen PSA had a minimum value of 1.5ng/ml and the maximum was 50.8ng/ml with mean value of 13.8ng/ml. The mean duration of surgery was 55.73 minutes and the mean duration of hospital stay was 3 days. The most common indication for TURP was lower urinary tract symptoms. We recorded four complications; capsule perforation, clot retention, hypotension and stress incontinence, 60 patients had no complications.
Conclusions: Transurethral resection of the prostate is an effective surgical treatment for benign prostatic hyperplasia, it is associated notable improvement in the patient’s quality of life and minimal complications.
Immediate effects of Chandra Nadi Shuddhi Pranayama on blood pressure, heart rate and rate pressure product among normal individuals: an experimental study
Authors: Shah Yashvi B. , Kamble Rutuja , Grover Pranjal 
Published: July 2024

Background: Chandra Nadi Shuddhi Pranayama is a type of alternate nostril breathing which is the control-positive inhalation and exhalation process. Alternate nostril breathing technique shows the best result in health improvement especially in controlling the blood pressure. It activates the parasympathetic nervous system which dilates blood vessels, decreases the heart rate which leads to reduce blood pressure. Many studies have been done to see effects of breathing exercises on cardiovascular system however, no such studies were done to see specific and immediate effect of Chandra Nadi Shuddhi on cardiovascular system. In this article, we will look how Chandra Nadi Shuddhi improves blood pressure, heart rate, and rate pressure product.
Methods: Ethical clearance and participant consent was taken. Study design was experimental study. The 80 subjects were taken by convenient sampling. Participants were asked to perform 27 rounds of the Chandra Nadi Shuddhi Pranayama and outcome measures were assessed before and immediately after performing Chandra Nadi Shuddhi. The normality of the data was assessed using parametric paired t test.
Results: Immediate effect of Chandra Nadi Shuddhi Pranayama showed that there was statistically significant decrease in blood pressure, heart rate and rate pressure product (p=0.0001, 0.0045, 0.0001 respectively)
Conclusions: There is immediate effects of Chandra Nadi Shuddhi Pranayama on individuals with normal blood pressure.These results suggest a possible role for this technique in helping to control hypertension, lower anxiety and depression, improve breathing and immunity.
KANT, FREGE, HILBERT Y LAS FUENTES DEL CONOCIMIENTO GEOMÉTRICO
Authors: Laserna Mario 
Published: July 2024

1. The scientific revolution of the 18th century was based in capability of predicting, using mathematical models, the structure of the spacio-temporal world. From there, aro se the notion of experimental science whose goals are determine wich of the theorical architectures correspond to spatio-temporal facts.
2. Producing the scientific revolution and destroying the psychologism inherent in the realism of Arostotle is the question "What are the mental structures that permit the creation and development ofthe scientific model achieved by mathematico-experimental physics? This is the problem conceming the sources of geometric knowledge proposed by Kant and later by Fregge and still later by David Hilbert.
3. These lead to a new concept of science seen as creativity of the human mind in order to systematize our experience in the spatio-temporal world inhabited by Horno sapiens.
Diagnostic Utility of Pre-Genomic Hepatitis B RNA in the Evaluation of HBV/HIV Coinfection
Authors: Sherman Kenneth , Rouster Susan , Meeds Heidi , Peters Marion , Blackard Jason , Horn Paul , Archampong Timothy , Kwara Awewura , Anderson Mark , Stec Michael , Cloherty Gavin 
Published: July 2024

Background: Newer biomarkers of Hepatitis B virus (HBV) infection and treatment response have not been well-characterized in individuals with HBV/HIV coinfection.
Methods: Pre-genomic RNA (pgRNA) and quantitative HBsAg (qHBsAg) were used to evaluate the associations with baseline characteristics. Participants included two separate groups – 236 with HBV/HIV coinfection enrolled in a cross-sectional cohort in Ghana and 47 from an HBV nucleoside/nucleotide treatment trial comparing tenofovir to adefovir in the United States.
Results: In both cohorts, HBe antigenemia was highly associated with pgRNA and HBV DNA levels. In the treatment cohort, pre-treatment pgRNA serum concentration was 7.0 log10 U/mL, and mean qHBsAg was 201,297 IU/mL. The observed treatment-associated decrease in pgRNA was consistent with a biphasic decline curve that reached second-phase kinetics following treatment week 12. Changes from baseline were significantly correlated with changes in serum ALT (r = - 0.518; P = 0.023) but not with changes in HBV DNA (r = 0.132, P = NS). qHBsAg also correlated with ALT change (r = - 0.488, P = 0.034).
Conclusion: pgRNA and qHBsAg represent newer biomarkers of HBV replication that may help monitor response and treatment outcomes. HBV pgRNA is highly associated with both HBeAg and ALT and may predict both active replication from the closed circular DNA (cccDNA) template as well as hepatic injury.
Random walk tests for the MENA stock returns
Authors: Asaad Zeravan Abdulmuhsen , Omer Bayar Mohamed Rasheed 
Published: July 2024

Purpose — The current study seeks to understand whether individual stock returns exhibit random movement and are not dependent (efficient at weak form) on fourteen out of sixteen actively traded Arab stock markets in the Middle East and North Africa (MENA) region, based on the size of the market value.Method — Various non-parametric methods, including autocorrelation test, variance ratio test, Phillips-Perron unit root test, and runs test, are used to assess the random walk hypothesis for daily data following the Covid-19 vaccination program. This analysis covers the period from January 3, 2021, to March 28, 2023.Result — The study results present evidence that all individual stock returns deviate from random walk behavior. However, only Kuwait, Jordan, and Palestine stock returns follow the random walk based on the run test results at a significance level of 10%. Therefore, it can be concluded that all stock returns are inefficient at the weak-form, suggesting that investors have opportunities for unexpected gains.Practical implications — The findings of this study suggest that investors in the MENA region may have opportunities for unexpected gains, as individual stock returns deviate from random walk behavior, highlighting the importance of considering market dynamics and employing informed investment strategies. Additionally, policymakers could benefit from understanding the inefficiencies in stock returns to implement measures that promote market stability and efficiency.
Pengelompokkan Daerah Rawan Demam Berdarah (DBD) di Jawa Timur Menggunakan Metode K-Means
Authors: Auditiyah Cellyn 
Published: July 2024

Tropical diseases are common in areas with tropical and subtropical climates. As a country with a tropical climate, Indonesia is vulnerable to various tropical diseases. A large number of tropical diseases can occur in the temperate climate zone, differing only in the frequency with which they are affected. Dengue hemorrhagic fever is a tropical disease in Indonesia. DHF occurs as a result of infection with the dengue virus which is transmitted through the bite of the female Aedes aegypti mosquito. The high prevalence of DHF in East Java requires a data collection process to identify areas that are frequently infected with DHF. Therefore, we need a clustering system that can help classify areas that often experience DHF cases. This study aims to find out which districts/cities have the predominant cases of dengue fever. The clustering method used is K-Means clustering. Based on the research conducted, 2 clusters were obtained with a silhouette coefficient value of 0.76. Cluster 1 covers 36 districts/cities and is an area with a low level of vulnerability to dengue fever, while cluster 2 covers 2 districts/cities and is an area with a high level of vulnerability to dengue fever.
Modeling Exchange Rate of Naira to Euro with the APLSTAR-GARCH model
Authors: Effiong Benjamin .A. , Okereke Emmanuel .W. , Omekara Chukwuemeka .O. , Acha Chigozie .K. , Akpan Emmanuel .A. 
Published: July 2024

Application of the asymmetric power logistic smooth transition autoregressive (APLSTAR) model proposed by [1] to naira/Euro exchange rate spanning from January, 2006 to April, 2021, which is a nonlinear macroeconomic time series was considered. The APLSTAR model was justifiably fitted to the series and the fit of the APLSTAR model compared with the fits of the competing models revealed that the APLSTAR model fits the data exchange rate of naira to Euro better than the other asymmetric STAR models. Lagrange Multiplier tests for autoregressive conditional heteroscedastic (ARCH) effects were carried out and there was no substantial evidence to reject the presence of ARCH effects in the set of residuals used. Hence, we compared hybrid smooth transition autoregressive-generalized ARCH (STAR-GARCH) models using model evaluation criteria. On balance, the APLSTAR-GARCH (0, 1) model outperforms the other models under consideration.
Hispanic-Serving Institutions Contributing to the Training and Diversity of the Public Health and Health Care Workforce
Authors: Concha Jeannie B. , Umucu Emre , Duarte-Gardea Maria , Gonzalez Azuri L. , Solis Guillermina R. , Loya Amanda M. , O’Dell Lara E. , Mathew Roy 
Published: July 2024

The University of Texas at El Paso (UTEP), a Hispanic Serving and Carnegie R1 institution, serves as a pathway for socioeconomically diverse Hispanic/Latino (H/L) health profession students via equal-access strategies. The Center for Institutional Evaluation, Research, and Planning data illustrates UTEP’s success in graduating H/L health professionals (i.e., allied health, nursing, pharmacy, and psychology) students between 2014 and 2023. Nearly 90% of these graduates are employed in Texas one year after graduation, and 85% remain employed after 10 years. ( Am J Public Health. 2024;114(S6):S472–S477. https://doi.org/10.2105/AJPH.2024.307655 ) [Formula: see text]
The Effect Of Interaction Between Non-Performing Loans And Operating Expenses On Capital Adequacy Ratio As Moderated By Return On Equity
Authors: Estiasih Soffia Pudji 
Published: July 2024

This study aims to analyze the effect of interaction between non-performing loans (NPL) and Operating Expenses to Operating Income (OEOI) ratios on capital adequacy ratio (CAR) as moderated by return on equity (ROE). A quantitative approach was used in this research. The data in this research were secondary ones and they were obtained from the annual financial statements for 2018-2020 period from commercial banks listed on Indonesian stock exchange (IDX). As many as 42 commercial banks served as the research population. From this number, using the requirement of having complete financial statements for 2018-2020 period as the criteria, 30 commercial banks were sampled purposively. The data were analyzed using multiple linear regression and moderating regression analysis (MRA). This study found that both NPL and operating expenses had a negative effect on CAR. However, while the former’s effect was significant, that of the latter was not. From the moderation regression analysis, it was revealed that ROE could not moderate the NPL’s effect on CAR, yet it could moderate the impact of OEOI on CAR.
The Inversion Location of Microleakage Source and Diffusion Backward Tracing Method Based on 3D Visual Information Model of Salt-Cavern Gas Storage
Authors: Zou Xianjian , Hu Hao , Yang Chunhe , Wang Tongtao , Chen Feng , Chen Jiasong , Wang Duocai 
Published: July 2024

Summary
The safe and stable operation of underground gas storage makes a positive contribution to national energy security. To improve the efficiency of real-time monitoring and early warning of gas leakage accidents at the wellsite of salt-cavern gas storage, an inversion location of the gas microleakage source and a backward tracing method of leakage diffusion are proposed. Through building a 3D visual information model of the salt-cavern gas storage based on building information modeling (BIM) technology and combining it with the advantages of the gas sensors, the real-time inversion location of the microleakage source and diffusion backward tracing in the wellsite can be realized. First, multiple point-type laser methane sensors were used to monitor the leakage of some key zones in real time, and a pan/tilt/zoom (PTZ) scanning laser methane telemeter was used to realize the real-time multidimensional space monitoring on-site from horizontal 360° to vertical 180°. Second, a 3D integrated monitoring platform is established to analyze the gas leakage source by combining the monitoring data and improving the mesh interpolation points. Finally, the whole data and wellsite information are imported into the 3D integrated monitoring platform to realize the inversion location of the microleakage source and the real-time monitoring of the leakage and diffusion state in the whole region. The monitoring precision of gas leakage concentration can be up to 1.0 ppm, and the location distance is within 0.1 m based on the numerical simulation of the 3D model and actual detected data from sensors in the platform. Compared with the technical means of manual assisted leak location, this method effectively solves the difficult problem of leakage monitoring and location accurately in the gas storage and can timely reduce the expansion and impact of leakage accidents.
Reinforced Visual Interaction Fusion Radiology Report Generation
Authors: Wang Liya , Chen Haipeng , Liu Yu , Lyu Yingda , Qiu Feng 
Published: July 2024

Abstract

The explosion in the number of more complex types of chest X-rays and CT scans in recent years has placed a significant workload on physicians, particularly in radiology departments, to interpret and produce radiology reports. There is therefore a need for more efficient generation of medical reports. In this paper, we propose the Reinforced Visual Interaction Fusion (RVIF) radiology report generation model, which adopts a novel and effective visual interaction fusion module, which is more conducive to extracting fused visual features of radiology images with clinical diagnostic significance and performing subsequent correlation. Sexual analysis and processing. In addition, a reinforcement learning step from image captioning to this task is introduced to further enhance the aligned diagnosis effect brought by the visual interactive fusion module to generate accurate and highly credible radiology reports. Quantitative experiments and visualization results prove that our model performs well on two public medical report generation datasets, IU X-Ray, and MIMIC-CXR, surpassing some SOTA methods. Compared with the SOTA model COMG+RL in 2024, the BLEU@1, 2, and 3 of the NLG metrics increased by 3.9%, 2.8%, and 0.5% respectively, METEOR increased by 2.2%, the precision P of the CE index increased by 0.4%, and the recall rate R increased by 1.5%, F1-score increased by 1.8%. Source code in https://github.com/200084/RVIF-Radiology-Report-Generation.
Fire and water: water quality impacts of landscape-scale disturbance by wildfire.
Authors: Shenton Mark David , Thompson Ross M , Kefford Ben J 
Published: July 2024

Abstract

Background: Wildfire plays an important role in determining ecosystem processes, composition, structure and condition, and is forecast to play a greater role under climate change. Wildfire affects the physicochemical and habitat characteristics of waterways, and the response in freshwater systems depends on characteristics of the fire, landscape and climate. Knowledge of fire effects on freshwater physiochemistry and habitat is predominantly based on suboptimal designed and short-medium term studies. Using a rigorous before-after-control-impact (BACI) study design and up to 28-years timeseries data, we examined if physicochemical and habitat variables changed following wildfire, and the duration of changes relative to unburnt sites in sub-alpine (hereafter alpine) and montane and sub-montane (montane hereafter) environments in south-eastern Australia.
Results:Of the variables hypothesised to change in response to fire, 8 out of 33 variables at alpine sites, and 7 out of 12 variables at montane sites, changed in line with our predictions. Four variables changed in the opposite direction to predictions. Of 11 variables measured at both sites in alpine and montane environments, 3 variables responded to the fire in only one environment (montane zone) and 1 variable (electrical conductivity) responded in both environments but in different directions. For 90% of response variables examined at both alpine sites (33 variables) and montane sites (12 variables) effects were not detectable beyond 2 years post-fire. The remaining 10% of variables examined were detected up to 8 years post fire at alpine sites, and for 2.5 years at montane sites. The duration of detectable effects was greater at alpine sites than montane sites.
Conclusions: We found no single consistent effect of fire on stream physicochemistry. Although some variables were found to respond to wildfire in a consistent way, the magnitude and duration of effects varied by site group (alpine versus montane) and site type (site burnt versus catchment burnt), illustrating the complexity of responses to wildfire. The complexity and inconsistency of responses of water physicochemical and habitat variables to wildfires reinforces the need for a better mechanistic understanding of the effects of fire on streams.