bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sustainable Catalysis: Rational Pd Loading on MIL‐101Cr‐NH2 for More Efficient and Recyclable Suzuki–Miyaura Reactions
Authors: Pascanu Vlad , Yao Qingxia , Bermejo Gómez Antonio , Gustafsson Mikaela , Yun Yifeng , Wan Wei , Samain Louise , Zou Xiaodong , Martín‐Matute Belén 
Published: November 2013

AbstractPalladium nanoparticles have been immobilized into an amino‐functionalized metal–organic framework (MOF), MIL‐101Cr‐NH2, to form Pd@MIL‐101Cr‐NH2. Four materials with different loadings of palladium have been prepared (denoted as 4‐, 8‐, 12‐, and 16 wt %Pd@MIL‐101Cr‐NH2). The effects of catalyst loading and the size and distribution of the Pd nanoparticles on the catalytic performance have been studied. The catalysts were characterized by using scanning electron microscopy (SEM), transmission electron microscopy (TEM), Fourier‐transform infrared (FTIR) spectroscopy, powder X‐ray diffraction (PXRD), N2‐sorption isotherms, elemental analysis, and thermogravimetric analysis (TGA). To better characterize the palladium nanoparticles and their distribution in MIL‐101Cr‐NH2, electron tomography was employed to reconstruct the 3D volume of 8 wt %Pd@MIL‐101Cr‐NH2 particles. The pair distribution functions (PDFs) of the samples were extracted from total scattering experiments using high‐energy X‐rays (60 keV). The catalytic activity of the four MOF materials with different loadings of palladium nanoparticles was studied in the Suzuki–Miyaura cross‐coupling reaction. The best catalytic performance was obtained with the MOF that contained 8 wt % palladium nanoparticles. The metallic palladium nanoparticles were homogeneously distributed, with an average size of 2.6 nm. Excellent yields were obtained for a wide scope of substrates under remarkably mild conditions (water, aerobic conditions, room temperature, catalyst loading as low as 0.15 mol %). The material can be recycled at least 10 times without alteration of its catalytic properties.
Pd‐Catalyzed Carbonylative α‐Arylation of Aryl Bromides: Scope and Mechanistic Studies
Authors: Nielsen Dennis U. , Lescot Camille , Gøgsig Thomas M. , Lindhardt Anders T. , Skrydstrup Troels 
Published: November 2013

AbstractReaction conditions for the three‐component synthesis of aryl 1,3‐diketones are reported applying the palladium‐catalyzed carbonylative α‐arylation of ketones with aryl bromides. The optimal conditions were found by using a catalytic system derived from [Pd(dba)2] (dba=dibenzylideneacetone) as the palladium source and 1,3‐bis(diphenylphosphino)propane (DPPP) as the bidentate ligand. These transformations were run in the two‐chamber reactor, COware, applying only 1.5 equivalents of carbon monoxide generated from the CO‐releasing compound, 9‐methylfluorene‐9‐carbonyl chloride (COgen). The methodology proved adaptable to a wide variety of aryl and heteroaryl bromides leading to a diverse range of aryl 1,3‐diketones. A mechanistic investigation of this transformation relying on 31P and 13C NMR spectroscopy was undertaken to determine the possible catalytic pathway. Our results revealed that the combination of [Pd(dba)2] and DPPP was only reactive towards 4‐bromoanisole in the presence of the sodium enolate of propiophenone suggesting that a [Pd(dppp)(enolate)] anion was initially generated before the oxidative‐addition step. Subsequent CO insertion into an [Pd(Ar)(dppp)(enolate)] species provided the 1,3‐diketone. These results indicate that a catalytic cycle, different from the classical carbonylation mechanism proposed by Heck, is operating. To investigate the effect of the dba ligand, the Pd0 precursor, [Pd(η3‐1‐PhC3H4)(η5‐C5H5)], was examined. In the presence of DPPP, and in contrast to [Pd(dba)2], its oxidative addition with 4‐bromoanisole occurred smoothly providing the [PdBr(Ar)(dppp)] complex. After treatment with CO, the acyl complex [Pd(CO)Br(Ar)(dppp)] was generated, however, its treatment with the sodium enolate led exclusively to the acylated enol in high yield. Nevertheless, the carbonylative α‐arylation of 4‐bromoanisole with either catalytic or stoichiometric [Pd(η3‐1‐PhC3H4)(η5‐C5H5)] over a short reaction time, led to the 1,3‐diketone product. Because none of the acylated enol was detected, this implied that a similar mechanistic pathway is operating as that observed for the same transformation with [Pd(dba)2] as the Pd source.
ChemInform Abstract: LuF[SeO3]: Structural Chameleon of Lanthanoid Fluoride Oxoselenates(IV).
Authors: Lipp Christian , Dinnebier Robert E. , Schleid Thomas 
Published: November 2013

AbstractThe title compound is synthesized by solid state reaction of Lu2O3, LuF3, and SeO2 using CsBr as a flux (750 °C, 5 d).
ChemInform Abstract: Crystal Structure, Phase Transitions, and Magnetic Properties of Iridium Perovskites Sr2MIrO6 (M: Ni, Zn).
Authors: Kayser P. , Martinez‐Lope M. J. , Alonso J. A. , Retuerto M. , Croft M. , Ignatov A. , Fernandez‐Diaz M. T. 
Published: November 2013

AbstractThe title compounds are prepared by high oxygen pressure/high temp.
ChemInform Abstract: Room‐Temperature Synthesis of Flower‐Like BiOX (X: Cl, Br, I) Hierarchical Structures and Their Visible‐Light Photocatalytic Activity.
Authors: Yin Shuang‐Feng , et al. et al. 
Published: November 2013

AbstractThe three‐dimensional flower‐like hierarchical title materials are synthesized from Bi(NO3)3 and L‐lysine dissolved in aqueous HX (X: Cl, Br, I) at pH 9 adjusted with aq.
ChemInform Abstract: Enantioselective Cycloaddition of Carbonyl Ylides with Arylallenes Using Rh2(S‐TCPTTL)4.
Authors: Krishnamurthi Janagiraman , Nambu Hisanori , Takeda Koji , Anada Masahiro , Yamano Akihito , Hashimoto Shunichi 
Published: November 2013

AbstractThe first catalytic asymmetric cycloaddition of carbonyl ylides, derived from diazoketoesters (I), with arylallenes (II) proceeds in a fully chemo‐ and regioselective manner to give 8‐oxabicyclo[3.2.1]octanes (III) (18 examples) with excellent enantio‐ and exo‐diastereoselectivity.
ChemInform Abstract: One‐Step Stereoselective Synthesis of Trisubstituted Monofluoroalkenes from 3,3,3‐Trifluoropropionates.
Authors: Lecea Mercedes , Grassin Adrien , Ferreiro‐Mederos Leticia , Choppin Sabine , Urbano Antonio , Carreno M. Carmen , Colobert Francoise 
Published: November 2013

AbstractAn access towards highly functionalized monofluoroalkenes is presented by the reaction of trifluoropropionates and Li or Mg nucleophiles.
ChemInform Abstract: Selective Reduction of Esters to Aldehydes under the Catalysis of Well‐Defined NHC‐Iron Complexes.
Authors: Li Haoquan , Castro Luis C. Misal , Zheng Jianxia , Roisnel Thierry , Dorcet Vincent , Sortais Jean‐Baptiste , Darcel Christophe 
Published: November 2013

AbstractIt provides a mild and efficient approach to aliphatic and aromatic aldehydes.
ChemInform Abstract: Iridium‐Catalyzed Enantioselective Hydrogenation of α,β‐Unsaturated Carboxylic Acids with Tetrasubstituted Olefins.
Authors: Song Song , Zhu Shou‐Fei , Li Yu , Zhou Qi‐Lin 
Published: November 2013

AbstractThe title methodology allows the preparation of chiral α‐substituted carboxylic acids in excellent yields and enantioselectivities.
ChemInform Abstract: Iron‐Catalyzed Three‐Component Reaction: Multiple C—C Bond Cleavages and Reorganizations.
Authors: Wang Peng , Liao Saihu , Zhu Jian‐Bo , Tang Yong 
Published: November 2013

AbstractA novel iron‐catalyzed C‐C bond cleavage and reorganization process is developed consisting of a three component reaction of crotonate derived phosphorous ylides (I), methyl diazoacetate (II) and a variety of α‐bromoacetophenones (III).
ChemInform Abstract: A Continuous Flow Solution to Achieving Efficient Aerobic anti‐Markovnikov Wacker Oxidation.
Authors: Bourne S. L. , Ley S. V. 
Published: November 2013

AbstractAn optimized continuous flow process is described to convert styrenes to aryl acetaldehydes using a Pd/Cu‐catalyzed anti‐Markovnikov addition of water followed by a Wacker‐type oxidation.
ChemInform Abstract: Domino Synthesis of Fluorine‐Substituted Polycyclic Aromatic Hydrocarbons: 1,1‐Difluoroallenes as Synthetic Platforms.
Authors: Fuchibe Kohei , Mayumi Yuka , Zhao Nan , Watanabe Shumpei , Yokota Misaki , Ichikawa Junji 
Published: November 2013

AbstractThis is a novel method for generating allylic CF2 cations from 1,1‐difluoroallenes with an indium(III) catalyst.
ChemInform Abstract: Arene C—H Bond Functionalization Coupling with Cyclization of Allenes.
Authors: Zeng Rong , Ye Juntao , Fu Chunling , Ma Shengming 
Published: November 2013

AbstractA rhodium(III)‐catalyzed reaction of N‐methoxybenzamides with tri‐ and tetrasubstituted 2,3‐allenols is developed to yield highly substituted 2,5‐dihydrofurans (III) and (VI).
ChemInform Abstract: Formation of Highly Functionalized Thiophenes by Reaction of Tetramethylthiourea, Acetylenic Esters, and α‐Haloketones.
Authors: Yavari Issa , Malekafzali Alaleh 
Published: November 2013

AbstractAddition of tetramethylthiourea (III) to dialkyl acetylenedicarboxylate (I) generates 1:1 zwitterionic intermediates which are trapped by α‐haloketones (II) to afford the functionalized thiophenes (IV).
ChemInform Abstract: Synthesis of Azetidines and Pyrrolidines via Iodocyclization of Homoallyl Amines and Exploration of Activity in a Zebrafish Embryo Assay.
Authors: Fossey John S. , et al. et al. 
Published: November 2013

AbstractA synthetically versatile protocol for the stereospecific cyclization of homoallyl amine derivatives (I) to deliver cis‐azetidines (III) and cis‐ or trans‐pyrrolidine derivatives (V)—(IX) is developed.
ChemInform Abstract: Asymmetric Synthesis and Molecular Docking Study of Enantiomerically Pure Pyrrolidine Derivatives with Potential Antithrombin Activity.
Authors: Ayan Seylan , Dogan Oezdemir , Ivantcova Polina M. , Datsuk Nikita G. , Shulga Dmitry A. , Chupakhin Vladimir I. , Zabolotnev Dmitry V. , Kudryavtsev Konstantin V. 
Published: November 2013

AbstractBoth enantiomers of pyrrolidine (III) are readily prepared by a zinc‐catalyzed asymmetric 1,3‐dipolar cycloaddition of tert‐butyl acrylate (II) with aldimine (I).
ChemInform Abstract: Bromophenyl Substituted Dithiafulvenes and Tetrathiafulvalene Vinylogues: Synthesis, Structure, and Electronic Properties.
Authors: Bouzan Stephen , Dawe Louise N. , Zhao Yuming 
Published: November 2013

AbstractOxidative dimerization of readily prepared bromophenyl substituted dithiafulvalenes (IIIa,b) offers a convenient synthesis of bis(bromophenyl) substituted tetrathiafulvalene vinylogues.
ChemInform Abstract: A New and Direct Route to 3‐Fluoromethyl Substituted Pyrazol‐4‐acrylates via Pd‐Catalyzed C—H Activation.
Authors: Wang Xiaoguang , Fang Xiang , Xiao Hongyuan , Gong Dongming , Yang Xueyan , Wu Fanhong 
Published: November 2013

AbstractThe first example of oxidative olefination via Pd‐catalyzed C4‐H activation of CF3‐ and CF2H‐substituted pyrazoles is reported.
ChemInform Abstract: Synthesis of Bis‐spirofused Thiapyrrolizidinooxindoles by 1,3‐Dipolar Cycloaddition
Authors: Shvets A. A. , Nelyubina Yu. V. , Lyssenko K. A. , Kurbatov S. V. 
Published: November 2013

Abstractof arylidene derivatives of rhodanine with azomethine ylide generated in situ from isatin and thiaproline
ChemInform Abstract: Five‐Fold Symmetric Penta‐Substituted Corannulene with Gelation Properties and a Liquid‐Crystalline Phase.
Authors: Mattarella Martin , Haberl Johannes M. , Ruokolainen Janne , Landau Ehud M. , Mezzenga Raffaele , Siegel Jay S. 
Published: November 2013

AbstractCompounds Ia‐c are prepared in a three step sequence.
ChemInform Abstract: Synthesis, Anticancer Activity and Photophysical Properties of Novel Substituted 2‐Oxo‐2H‐chromenylpyrazolecarboxylates.
Authors: Kumar J. Ashok , Saidachary G. , Mallesham G. , Sridhar B. , Jain Nishant , Kalivendi Shashi Vardhan , Rao V. Jayathirtha , Raju B. China 
Published: November 2013

AbstractTitle compounds (III) and (V) are synthesized by [3 + 2] cycloaddition of hydrazones (I) and (IV) with acetylenedicarboxylic ester (II), respectively.
ChemInform Abstract: Diversity‐Oriented General Protocol for the Synthesis of Privileged Oxygen Scaffolds: Pyrones, Coumarins, Benzocoumarins and Naphthocoumarins.
Authors: Goel Atul , Taneja Gaurav , Raghuvanshi Ashutosh , Kant Ruchir , Maulik Prakas R. 
Published: November 2013

AbstractTitle compounds such as (IV), (VIII), and (XIII) are prepared through carbanion‐induced ring transformation of lactones such as (I), (V), and (X) with various methylene carbonyl compounds such as (II) and (VI), followed by DDQ‐mediated unprecedented oxidative cleavage of the C—C double bond.
ChemInform Abstract: A Catalytic Michael/Horner—Wadsworth—Emmons Cascade Reaction for Enantioselective Synthesis of Thiochromenes.
Authors: Choudhury Abhijnan Ray , Mukherjee Santanu 
Published: November 2013

AbstractAn enantioselective sulfa‐Michael/Horner—Wadsworth—Emmons reaction cascade is developed using a bifunctional urea catalyst.
ChemInform Abstract: Copper‐Catalyzed Enantioselective Intramolecular N‐Arylation, an Efficient Method for Kinetic Resolution.
Authors: Yang Wenqiang , Long Yan , Zhang Shasha , Zeng Youlin , Cai Qian 
Published: November 2013

AbstractKinetic resolution by copper‐catalyzed N‐arylation is reported for the first time.
ChemInform Abstract: Synthesis and Structure of New Imidazo‐ and Pyrazolo[5,1‐d][1,2,3,5]thiatriazines Based on the Reaction of Diazoazoles with Acyl Isothiocyanates Controlled by S···O Interaction.
Authors: Sadchikova Elena V. , Bakulev Vasiliy A. , Subbotina Julia O. , Privalova Darya L. , Dehaen Wim , Van Hecke Kristof , Robeyns Koen , Van Meervelt Luc , Mokrushin Vladimir S. 
Published: November 2013

AbstractCycloaddition reactions of 5‐diazopyrazoles and 5‐diazoimidazoles with acyl isothiocyanates give thiatriazine derivatives.
ChemInform Abstract: Antimicrobial and Antioxidant Isoflavonoid Derivatives from the Roots of Amphimas pterocarpoides.
Authors: Saah Edwige P. Fodja , Sielinou Valerie Tedjon , Kuete Victor , Lacmata Stephen T. , Nkengfack Augustin E. 
Published: November 2013

Abstractisolation and structure elucidation of amphiisoflavone (I)
ChemInform Abstract: An Approach to Hyperolactone C and Analogues Using Late Stage Conjugate Addition on an Oxonium Ylide‐Derived Spirofuranone.
Authors: Hodgson David M. , Moreno‐Clavijo Elena , Day Sophie E. , Man Stanislav 
Published: November 2013

AbstractA stereocontrolled approach to spirolactone (III) is described.
ChemInform Abstract: Poly(2‐oxazoline) Functionalized Surfaces: From Modification to Application
Authors: Tauhardt Lutz , Kempe Kristian , Gottschaldt Michael , Schubert Ulrich S. 
Published: November 2013

AbstractReview: different approaches to immobilize the title biocompatible polymers on surfaces as well as properties and applications; 50 refs.
Synthesis and Biological Evaluation of Biphenyl Amides That Modulate the US28 Receptor
Authors: Kralj Ana , Kurt Elif , Tschammer Nuska , Heinrich Markus R. 
Published: November 2013

AbstractTo prepare and biologically evaluate 38 new potential US28 allosteric modulators, we employed a straightforward synthetic route involving radical arylation. The study was based on a former lead structure but with the dihydroisoquinolinone moiety replaced by substituted biphenyls. The investigation of structure–activity relationships among the new biphenyl‐derived ligands led to a preliminary pharmacophore model and the discovery of four promising candidates with full inverse agonist properties.
Energy Relay from an Unconventional Yellow Dye to CdS/CdSe Quantum Dots for Enhanced Solar Cell Performance
Authors: Narayanan Remya , Das Amrita , Deepa Melepurath , Srivastava Avanish Kumar 
Published: November 2013

AbstractA new design for a quasi‐solid‐state Forster resonance energy transfer (FRET) enabled solar cell with unattached Lucifer yellow (LY) dye molecules as donors and CdS/CdSe quantum dots (QDs) tethered to titania (TiO2) as acceptors is presented. The Forster radius is experimentally determined to be 5.29 nm. Sequential energy transfer from the LY dye to the QDs and electron transfer from the QDs to TiO2 is followed by fluorescence quenching and electron lifetime studies. Cells with a donor–acceptor architecture (TiO2/CdS/CdSe/ZnS‐LY/S2−‐multi‐walled carbon nanotubes) show a maximum incident photon‐to‐current conversion efficiency of 53 % at 530 nm. This is the highest efficiency among Ru‐dye free FRET‐enabled quantum dot solar cells (QDSCs), and is much higher than the donor or acceptor‐only cells. The FRET‐enhanced solar cell performance over the majority of the visible spectrum paves the way to harnessing the untapped potential of the LY dye as an energy relay fluorophore for the entire gamut of dye sensitized, organic, or hybrid solar cells.
Double‐Wall Carbon Nanotube–Porphyrin Supramolecular Hybrid: Synthesis and Photophysical Studies
Authors: Vizuete María , Gómez‐Escalonilla María J. , Fierro José Luis G. , Atienzar Pedro , García Hermenegildo , Langa Fernando 
Published: November 2013

AbstractDouble‐wall carbon nanotubes (DWCNTs) with pyridyl units covalently attached to the external wall through isoxazolino linkers and carboxylic groups that have been esterified by pentyl chains are synthesized. The properties of these modified DWCNTs are then compared with an analogous sample based on single‐wall carbon nanotubes (SWCNTs). Raman spectroscopy shows the presence of characteristic radial breathing mode vibrations, confirming that the samples partly retain the integrity of the nanotubes in the case of DWCNTs, including the internal and external nanotubes. Quantification of the pyridyl content for both samples (DWCNT and SWCNT derivatives) is based on X‐ray photoelectron spectroscopy and thermogravimetric profiles, showing very similar substituent load. Both pyridyl‐containing nanotubes (DWCNTs and SWCNTs) form a complex with zinc porphyrin (ZnP), as evidenced by the presence of two isosbestic points in the absorption spectra of the porphyrin upon addition of the pyridyl‐functionalized nanotubes. Supramolecular complexes based on pyridyl‐substituted DWCNTs and SWCNTs quench the emission and the triplet excited state identically, through an energy‐transfer mechanism based on pre‐assembly of the ground state. Thus, the presence of the intact inner wall in DWCNTs does not influence the quenching behavior, with respect to SWCNTs, for energy‐transfer quenching with excited ZnP. These results sharply contrast with previous ones referring to electron‐transfer quenching, in which the double‐wall morphology of the nanotubes has been shown to considerably reduce the lifetime of charge separation, owing to faster electron mobility in DWCNTs compared to SWCNTs.
Cochrane in context: Vaccines for measles, mumps and rubella in children
Authors: Demicheli Vittorio , Rivetti Alessandro , Debalini Maria Grazia , Di Pietrantonj Carlo , Robinson Joan 
Published: November 2013

AbstractCochrane Review: Vaccines for measles, mumps and rubella in children Demicheli V, Rivetti A, Debalini MG, Di Pietrantonj C. Vaccines for measles, mumps and rubella in children. Cochrane Database of Systematic Reviews 2012, Issue 2. Art. No.: CD004407. DOI: 10.1002/14651858.CD004407.pub3This companion piece to the review, “Vaccines for measles, mumps and rubella in children,” contains the following pieces:

The abstract of the review
A commentary from one or more of the review authors, explaining why the review team felt the review was an important one to produce
A commentary from Joan Robinson, Editor‐in‐chief, outlining the review's findings
A review of clinical practice guidelines from the American Academy of Pediatrics, the Canadian Paediatric Society and the National Institute for Health and Care Excellence (NICE), United Kingdom
Some other recently published references on this topic
Catalytic Asymmetric Synthesis of Dihydrofurans and Cyclopentenols with Tertiary Stereocenters
Authors: Wu Zhongtao , Madduri Ashoka V. R. , Harutyunyan Syuzanna R. , Minnaard Adriaan J. 
Published: November 2013

AbstractA new asymmetric synthesis of dihydrofurans and cyclopentenols has been developed and is based on the copper‐catalyzed 1,2‐addition of Grignard reagents to enones in combination with Sonogashira coupling/cyclization or ring‐closing metathesis. By this approach, dihydrofurans with an oxygen‐containing tertiary stereocenter and chiral tertiary cyclopentenols are efficiently prepared. The absolute stereochemistry of the products has been established.
Effects of Cylindrospermopsis raciborskii (cyanobacteria) on the swimming behavior of Daphnia (cladocera)
Authors: Ferrão-Filho Aloysio S. , Soares Maria Carolina S. , Lima Ramon S. , Magalhães Valeria F. 
Published: November 2013

Abstract

The present study aimed to test the effects of raw water samples from a eutrophic reservoir and of a saxitoxin-producing strain of Cylindrospermopsis raciborskii on the swimming behavior of 2 key herbivore species of Daphnia. Two complementary approaches were used, acute bioassays and behavioral assays using an automated movement tracking system for measuring the following activity parameters: swimming time, resting time, distance traveled, and mean velocity. In both assays, animals were exposed to field samples or to toxic filaments in different concentrations and observed for 2 h to 3 h. In the acute bioassays, there was a decrease in the number of swimming individuals during the exposure period and a recovery following removal from toxic algae. A significant relationship was found between median effective concentration and the saxitoxin content of seston (r2 = 0.998; p = 0.025) in the acute bioassays with raw water samples. Behavioral assays also showed significant effects in the activity parameters with both field samples and the strain of C. raciborskii, with some recovery during the exposure period. Both approaches corroborated previous research on the effects of neurotoxic C. raciborskii on the swimming activity of Daphnia, and these effects are compatible with the mechanism of action of saxitoxins. The present study showed that activity parameters of aquatic organisms may be a useful tool in the evaluation of sublethal toxicity and detection of neurotoxins in raw water. Environ Toxicol Chem 2014;33:223–229. © 2013 SETAC
Description of the genetic analysis workshop 11 collaborative study on the genetics of alcoholism
Authors: Begleiter H. , Reich T. , Nurnberger J. , Li T.K. , Conneally P.M. , Edenberg H. , Crowe R. , Kuperman S. , Schuckit M. , Bloom F. , Hesselbrock V. , Porjesz B. , Cloninger C.R. , Rice J. , Goate A. 
Published: November 2013

AbstractProblem 1 of Genetic Analysis Workshop 11 consists of data from a family study of the genetics of alcoholism and related traits contributed by the six centers making up the National Institute for Alcohol Abuse and Alcoholism sponsored by the Collaborative Study on the Genetics of Alcoholism (COGA). The family data included 1,214 members of 105 pedigrees ascertained for having three or more individuals affected with alcoholism. Data available to workshop participants included clinical phenotypes, personality measures, smoking behavior, event‐related potentials, platelet monamine oxidase B activity, and a genome scan of 296 markers.