bluuebunny/crossref_metadata_2025_split huggingface dataset:
Identifying and Characterizing Infrared Excesses in the Spitzer Kepler Survey (SpiKeS)
Authors: Skorpen Sydney O. , Morales Farisa Y. , Gorjian Varoujan , Werner Michael W. , Bryden Geoffrey 
Published: August 2024

Abstract
We report our search for infrared excesses in the Spitzer/Infrared Array Camera survey of the Kepler field at 3.6 and 4.5 μm. The Spitzer Kepler Survey contains ∼190,000 targets, which we reduce to ∼117,000 targets after applying multiple filters to arrive at a high-quality sample for spectral energy distribution fitting. Of the ∼117,000, we find 11 Sun-like stars (T
eff ∼ 6000 K) with infrared excesses of high significance (>4σ) ranging from 10% to 40% above the photosphere at 4.5 μm, which is characteristic of debris disk systems. Blackbody fits of the infrared excesses for the 11 debris disk candidates suggest dust temperatures of 400–1400 K. None of the candidates have reported exoplanet detections. High-quality 1–5 μm or longer spectra or photometry would be necessary to confirm the candidates as debris disk systems.
PINT: Maximum-likelihood Estimation of Pulsar Timing Noise Parameters
Authors: Susobhanan Abhimanyu , Kaplan David L. , Archibald Anne M. , Luo Jing , Ray Paul S. , Pennucci Timothy T. , Ransom Scott M. , Agazie Gabriella , Fiore William , Larsen Bjorn , O’Neill Patrick , van Haasteren Rutger , Anumarlapudi Akash , Bachetti Matteo , Bhakta Deven , Champagne Chloe A. , Cromartie H. Thankful , Demorest Paul B. , Jennings Ross J. , Kerr Matthew , Levina Sasha , McEwen Alexander , Shapiro-Albert Brent J. , Swiggum Joseph K. 
Published: August 2024

Abstract

PINT is a pure-Python framework for high-precision pulsar timing developed on top of widely used and well-tested Python libraries, supporting both interactive and programmatic data analysis workflows. We present a new frequentist framework within PINT to characterize the single-pulsar noise processes present in pulsar timing data sets. This framework enables parameter estimation for both uncorrelated and correlated noise processes, as well as model comparison between different timing and noise models in a computationally inexpensive way. We demonstrate the efficacy of the new framework by applying it to simulated data sets as well as a real data set of PSR B1855+09. We also describe the new features implemented in PINT since it was first described in the literature.
Evolution of QPOs in GX 339–4 and EXO 1846–031 with Insight-HXMT and NICER
Authors: Zhang Zuobin , Liu Honghui , Rawat Divya , Bambi Cosimo , Misra Ranjeev , Wang Pengju , Ji Long , Zhang Shu , Zhang Shuangnan 
Published: August 2024

Abstract
We conduct a spectral and timing analysis of GX 339−4 and EXO 1846−031 with the aim of studying the evolution of type-C quasiperiodic oscillations (QPOs) with spectral parameters. The high-cadence data from Insight-HXMT and NICER allow us to track the evolution of QPOs and spectra simultaneously. Type-C QPOs appear at the end of the low–hard state and/or the hard–intermediate state. Our results reveal that the QPO frequency is closely related to the inner disk radius and mass accretion rate in the two sources. This correlation aligns well with the dynamic frequency model of a truncated disk.
Radioactive Gamma-Ray Lines from Long-lived Neutron Star Merger Remnants
Authors: Chen Meng-Hua , Li Li-Xin , Liang En-Wei 
Published: August 2024

Abstract
The observation of a kilonova AT2017gfo associated with the gravitational wave event GW170817 provides the first strong evidence that neutron star mergers are dominant contributors to the production of heavy r-process elements. Radioactive gamma-ray lines emitted from neutron star merger remnants provide a unique probe for investigating the nuclide composition and tracking its evolution. In this work, we studied the gamma-ray line features arising from the radioactive decay of heavy nuclei in the merger remnants based on the r-process nuclear reaction network and the astrophysical inputs derived from numerical relativity simulations. The decay chain of

50

126

Sn (T
1/2 = 230 kyr) →

51

126

Sb (T
1/2 = 12.35 days) →

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126

Te (stable) produces several bright gamma-ray lines with energies of 415, 667, and 695 keV, making it the most promising decay chain during the remnant phase. The photon fluxes of these bright gamma-ray lines reach ∼10−5
γ cm−2 s−1 for Galactic merger remnants with ages less than 100 kyr, which can be detected by the high energy resolution MeV gamma-ray detectors like the MASS mission.
Écoute plurielle dans un Groupe de travail clinique
Authors: Fry Manou , Hours Armelle , Lhopital Marc , Sage Bernard 
Published: August 2024

« Écoute plurielle dans un Groupe de travail clinique. » Le constat de la désertion de la pensée psychanalytique dans les institutions de soins et médico-sociales a entraîné quatre psychanalystes, exerçant eux-mêmes en institution, à proposer un dispositif groupal original aux professionnels en souffrance dans les institutions. Un travail d’écoute à quatre a pu se mettre en place. Des positions différenciées visent le déploiement de l’associativité groupale pour mobiliser, à partir de la richesse des échanges, l’élaboration des enjeux cliniques et relancer la capacité et le plaisir de penser à plusieurs. Des séquences de matériel de séance illustrent le propos.
La transdisciplinarité en pratique périnatale : enjeux et fonctions
Authors: Urgese Svetoslava 
Published: August 2024

« La transdisciplinarité en pratique périnatale : enjeux et fonction. » Les équipes pluriprofessionnelles qui prennent soin des parents et de leur bébé en période périnatale ont à composer avec l’entre-deux auquel convoque cette rencontre primordiale. Cet « entre » est également à envisager comme un espace à soigner et cultiver dans la dynamique transdisciplinaire entre les professionnels. Par ailleurs, la groupalité adossée à un arrière-fond institutionnel constitue une enveloppe, cette fois autour des parents et de leur bébé. Cet article explore ainsi les dynamiques du travail pluriprofessionnel qui se noue à l’endroit de ces deux espaces, l’intermédiaire et le contour groupal. C’est entre ces espaces que se met en mouvement la transdisciplinarité au sein de la groupalité pluriprofessionnelle, en étayage sur une sensorialité partagée.
Effets iatrogènes des mesures d’assistance éducative sur le lien mère-bébé
Authors: Dobrzynski Anne-Claire 
Published: August 2024

« Effets iatrogènes des mesures d’assistance éducative sur le lien mère-bébé. Effets maturatifs d’un accompagnement transdisciplinaire. » À travers la situation d’un bébé de 7 mois et de sa mère, accompagnées dans le cadre d’une mesure judiciaire d’investigation éducative, l’autrice propose de montrer dans un premier temps les effets iatrogènes potentiels des mesures de placement à l’endroit de la naissance à la parentalité déjà fragilisée, et des liens mère-bébé. Une approche transdisciplinaire prenant en compte les enjeux inter-institutionnels permet d’accueillir les dépôts archaïques, afin de les transformer et de constituer un tissu inter-institutionnel résistant et consistant, produisant un portage contenant et maturatif de la parentalité et du lien mère-bébé.
Tisser une enveloppe en thérapie familiale psychanalytique sur la trame de l’institution
Authors: Gianèse-Madelaine Catherine 
Published: August 2024

« Tisser une enveloppe en thérapie familiale psychanalytique sur la trame de l’institution. » La thérapie familiale psychanalytique permet d’accueillir la souffrance des liens, d’accompagner un processus d’affiliation, notamment pour des familles adoptantes. Ce travail psychique s’effectue en élaborant la question du renoncement, notamment aux idéaux, dans un processus groupal intense et complexe, qui engage famille et thérapeutes. Une situation clinique met en lumière comment les résonances entre la dynamique familiale, celle du néo-groupe en séance et celle de l’intertransfert des thérapeutes, eux-mêmes inclus dans un travail institutionnel large, représente une voie d’élaboration.
Les enjeux de la pluridisciplinarité dans l’accompagnement des adolescents incarcérés
Authors: Vavassori David , Harrati Sonia 
Published: August 2024

« Les enjeux de la pluridisciplinarité dans l’accompagnement des adolescents incarcérés ». À partir de notre expérience de psychologue clinicien en établissement pénitentiaire pour mineur (EPM) dans le cadre d’interventions auprès d’équipes pluridisciplinaires, notre objectif est de présenter des pistes de réflexions sur les processus en jeux dans l’articulation entre le pluri-institutionnel, le pluridisciplinaire et l’interdisciplinaire en EPM. Nous nous interrogerons sur la dynamique institutionnelle qui résulte de cette injonction à travailler en équipe pluridisciplinaire et sur les enjeux de la prise en compte des mouvements intersubjectifs et de leurs résonances sur les prises en charge des adolescents incarcérés.
Un cas d’inceste : suivi psychothérapeutique individuel et familial en institution psychiatrique
Authors: Blacioti Elena 
Published: August 2024

« Un cas d’inceste : suivi psychothérapeutique individuel et familial en institution psychiatrique. » L’auteur présente le cas clinique d’une jeune adulte, victime d’inceste, hospitalisée dans un service de psychiatrie adulte. La prise en charge psychothérapique, individuelle et familiale aide à comprendre la dynamique des topiques intrapsychique, intersubjective et transubjective de cette clinique de l’inceste afin de prendre en charge la violence intrafamiliale et les agirs. Le processus de parentification met en évidence un renversement générationnel, des liens d’emprise, une confusion des rôles et des places, un climat incestuel et semble contribuer à l’accomplissement des relations incestueuses. Ce double dispositif permet de créer des espaces différenciés et de pouvoir reprendre un travail de symbolisation, de mentalisation et d’élaboration des traumatismes tant individuels que familiaux.
ANALYZING THE FACTORS ASSOCIATED WITH WALKABILITY IN A CAMPUS SETTING FROM USERS' PERSPECTIVES
Authors: Doğmuşöz Burçin B 
Published: August 2024

ABSTRACT
Due to its potential to encourage more sustainable urban settings, the term walkability has gained importance in recent years. Consequently, there has been an increased interest among researchers in understanding which factors encourage walkability. In this context, university campuses, as a part of a city, offer opportunities for walkability studies to investigate the factors affecting walking behavior. Although there are a few campus walkability studies in literature, further research is still needed to add to the body of knowledge in various geographic and climatic situations. This research aims to understand better factors that influence campus users’ walking behavior from the viewpoints of the campus community by investigating built environment characteristics associated with the campus and its surroundings walkability and other influencing factors. An online questionnaire was established for this purpose. Statistical analyses were conducted using multivariable logistic regression to examine variables that could influence the participants’ willingness to walk. Attitudes toward walking behavior and physical features of the built environment were all found to be significant determinants of campus users’ willingness to walk. In the current study, however, other influencing factors that were identified as significant factors in the literature were not found significant to predict willingness to walk. Moreover, these findings can inform municipal policy-makers and campus management about how to create a walkable campus environment and promote increased walking at a university.
Podosome Nucleation Is Facilitated by Multivalent Interactions between Syk and ITAM-containing Membrane Complexes
Authors: Ghasempour Sina , Muise Aleixo M , Freeman Spencer A 
Published: August 2024

Abstract
Immune cells survey their microenvironment by forming dynamic cellular protrusions that enable chemotaxis, contacts with other cells, and phagocytosis. Podosomes are a unique type of protrusion structured by an adhesive ring of active integrins that surround an F-actin–rich core harboring degradative proteases. Although the features of podosomes, once-established, have been well defined, the steps that lead to podosome formation remain poorly understood by comparison. In this study, we report that spleen tyrosine kinase (Syk) is a critical regulator of podosome formation. Deletion of Syk or targeting its kinase activity eliminated the ability for murine macrophages to form podosomes. We found that the kinase activity of Syk was important for the phosphorylation of its substrates, HS1 and Pyk2, both of which regulate podosome formation. Additionally, before podosomes form, we report that the tandem Src homology 2 domains of Syk afforded multivalent clustering of ITAM-containing adaptors that associated with integrins to structure platforms that initiate podosomes. We therefore propose that Syk has a dual role in regulating podosomes: first, by facilitating the assembly of multivalent signaling hubs that nucleate their formation and second, by sustaining tyrosine kinase activity of the podosomes once they form against their substrates. In cells expressing recently identified gain-of-function variants of SYK, podosomes were dysregulated. These results implicate SYK in the (patho)physiological functions of podosomes in macrophages.
Diffusion-weighted Imaging: New Paradigm in Diagnosis of Early Acute Pancreatitis
Authors: Arora Manali , Lakhera Devkant , Rawat Kanica , Thakker Vishal , Randhawa Lovepreet Singh , Patel Amisha , Agarwal Rachit , Azad Rajiv Kumar 
Published: August 2024

Background:
Diffusion-weighted imaging (DWI) has come up as a newer diagnostic modality for the diagnosis of early functional changes in various organs including the pancreas. DWI has shown the ability of early and accurate diagnosis of inflammatory pathologies, before the appearance of morphological changes on imaging.

Objectives:
The objectives of this study were to study the diagnostic accuracy of DWI in the diagnosis of early acute interstitial pancreatitis.

Materials and Methods:
The present retrospective observational study was conducted at the department of radiodiagnosis of a tertiary teaching hospital for 1 year. Fifty patients who underwent magnetic resonance imaging of the pancreas with clinical or laboratory diagnosis of early pancreatitis were included in the study. The diagnostic accuracy of DWI was analyzed on the basis of quantitative (apparent diffusion coefficient [ADC] values) evaluation in the diagnosis of early acute pancreatitis. Threshold values for ADC were derived for differentiation of inflamed versus normal pancreas. Sensitivity, specificity, positive predictive value (PPV), and negative predictive values (NPV) were obtained by drawing the receiver operating characteristic (ROC) curve.

Results:
The mean ADC values in the patient group (0.882 × 10−3 mm2/s ± 0.102) were significantly lower than the control group (1.178 × 10−3 mm2/s ± 0.232) with P < 0.001. The ROC curve deciphered a cutoff value of 0.937 × 10−3 mm2/s with a sensitivity of 84%, specificity of 86%, PPV of 85.71%, and NPV of 84.31% for diagnosis of acute pancreatitis using quantitative ADC values.

Conclusion:
DWI can thus be a succinct modality for early diagnosis of pancreatitis with excellent diagnostic accuracy and superlative advantage of lack of contrast and radiation in comparison to computed tomography scan.
Effect of Stress on Sleep Quality among Medical Students: A Cross-sectional Study at Jazan University, Saudi Arabia
Authors: Sayed Ahmed I. , Mobarki Sarah J. , Oberi Imtenan A. , Omar Yazan Z. , Moafa Sarah H. , Ayoub Raum A. , Ajeebi Yara , Hakami Faisal , Hakami Abdulrahman , Somaili Mohammed 
Published: August 2024

Introduction:
It has long been understood that sleep is a necessary therapeutic element of human physiology and is crucial for healthy functioning, mental health, and quality of life. Medical students frequently minimize their sleep and habits to cope with their workload and their stressful lives, which has a negative influence on both mental health and academic performance. The purpose of this study was to evaluate the prevalence of stress and its effect on sleep quality among medical students (in both the preclinical and clinical years) at Jazan University in Saudi Arabia.

Materials and Methods:
A cross-sectional research design was applied in this study. The sample constituted medical students at Jazan University, Jazan region, Saudi Arabia. A self-administered online survey was distributed actively to measure the variables of interest.

Results:
This study examined the sleep quality and psychological distress among 347 students. The findings revealed that a significant proportion of students experienced sleep difficulties, with 52.8% reporting mild sleep problems and 46.6% reporting moderate sleep difficulties. In addition, a notable percentage of participants (28.2%) reported very high psychological distress, while 27.4% experienced severe psychological distress.

Conclusions:
This study found that medical students had a high level of stress and poor sleep quality, which led to unhealthy habits, such as consuming many energy drinks. Hence, it is recommended that concerns should be addressed to minimize the risk of developing chronic illnesses.
Association of anxiety, depression and sleep quality with binge-watching behavior in college students – An observational study
Authors: Bandla Shailaja , Lella Srikanth , Kola Amulya , Parvathaneni Krishna Mohan , Rani Jhansi 
Published: August 2024

Abstract

Background:
Binge-watching is the habit of watching television or series for extended periods, often involving consecutive viewing of multiple episodes from the same series. This phenomenon is prevalent among adolescents and young adults, often likened to addiction due to its pervasive nature. It is intertwined with detrimental effects on physical health, mental well-being, social engagement, and academic performance. Neither the International Classification of Diseases, eleventh revision nor the Diagnostic and Statistical Manual of Mental Disorders, fifth edition have acknowledged binge-watching as a disorder.

Aim:
The aim of the study was to study the association of anxiety, depression, and sleep quality with binge-watching behavior in college students.

Methodology:
This is a cross-sectional study conducted on students belonging to medical, dental, engineering, and arts. Sociodemographic details were taken. Binge-watching Engagement and Symptoms Questionnaire, Beck’s Anxiety Inventory (BAI), Beck’s Depression Inventory (BDI), and Pittsburgh Sleep Quality Index (PSQI) were applied. Data were analyzed using SPSS version 25.0. The Chi-square test and analysis of variance were used.

Results:
In our study, which included 400 students from various academic specialities, 364 (91%) displayed binge-watching behavior. A significant association was found between binge-watching and measures of anxiety (BAI, P = 0.02), depression (BDI, P = 0.01), and sleep quality (PSQI, P = 0.03).

Conclusions:
A large proportion of students exhibited binge-watching behaviors. These findings highlight the importance of addressing binge-watching behaviors in promoting overall well-being among students. There is a need to monitor this behavior due to its deleterious effects.
Frozen section versus imprint cytology for evaluation of intraoperative sentinel lymph node biopsy in breast cancer patients: a prospective study
Authors: Moussa Rabab A. , Shaban Shimaa H. , Mahran Mohamed H. , Herdan Rania A. 
Published: August 2024

Background
Currently, two methods are commonly used for intraoperative examination of the sentinel lymph nodes (SLNs) biopsy in breast cancer (BC); imprint cytology (IC) and frozen section (FS).

Aim
Assessing the outcomes of the intraoperative SLN IC evaluation and comparing them to those of FS.

Methods
Eighty-seven patients have been diagnosed with T1-T2 BC. Sentinel nodes were detected using the blue dye injection technique intraoperatively. From each SLN, two slides of touch imprint were provided for imprint cytology evaluation and excised SLNs were then sent for frozen section.

Results
Histological examination of SLNs revealed 10 positive cases and 77 negative cases. Regarding IC, positive SLNs were detected in 8 cases and 79 case showed negative results. For FS, positive SLNs were detected in 11 case and 76 case were negative. Regarding IC, the sensitivity and specificity were 60% and 97.4%, respectively, whereas the sensitivity and specificity reach 90% and 97.4% for FS. Overall accuracy was 93.1% for IC and 96.6% for FS.

Conclusion
Intraoperative SLN diagnosis by imprint cytology in many aspects, could be comparable to that obtained from FS examination. Imprint cytology is simple, fast, easily performed, inexpensive, and highly accurate way of intraoperative SLN diagnosis in BC patients.
Immunohistochemical expression of Hairy and Enhancer of Split 1 (HES1) protein in breast carcinoma
Authors: Shibel Passant E.E. , Mohamed Alyaa A.E. , El Aziz Ahmed M. Abd , Khairy Rasha A. 
Published: August 2024

Background
Hairy and Enhancer of Split 1 (HES1) is a transcription factor involved in cell differentiation, proliferation, and in various cancer progression. Recently, HES1 was addressed as a potential biomarker that induces stem cell features in breast cancer and stimulates epithelial-mesenchymal transition in triple-negative breast cancer (TNBC).

Aim
This study aimed to assess HES1 immunohistochemical (IHC) expression in invasive breast carcinoma and correlate it with the clinicopathological variables and different molecular subtypes of the cases.

Patients and methods
IHC was conducted on 76 paraffin blocks with an anti-HES1 monoclonal antibody, and a final IHC score was calculated based on staining intensity and percentage of positively stained cells. A final IHC of greater than or equal to 4 was considered an HES1 positive expression.

Results
HES1 expression was positive in 18 (23.7%) cases and was significantly associated with breast cancer HER2-enriched molecular subtype, followed by triple-negative breast cancer (P<0.05). HES1 expression was also significantly associated with estrogen and progesterone receptor negativity and HER2 overexpression (P<0.05). Positive HES1 expression was associated with high tumor grade, advanced stage, high Ki-67 proliferation index, and presence of tumor vascular emboli, although it did not reach statistical significance (P>0.05).

Conclusion
Our study demonstrated that the HES1 protein showed a significantly higher expression in nonluminal breast cancer subtypes. In addition, it could have a potential role in the growth and spread of breast cancer cells. These findings suggest that HES1 is a possible promising target for therapeutic interventions.