bluuebunny/crossref_metadata_2025_split huggingface dataset:
Relationship between metabolic syndrome and periodontitis in 80‐year‐old Japanese subjects
Authors: Minagawa K. , Iwasaki M. , Ogawa H. , Yoshihara A. , Miyazaki H. 
Published: May 2014

Background and ObjectivePotentially significant associations between metabolic syndrome (MetS) and periodontitis have been reported in recent studies; however, there are limited data on their association in the very old. The aim of this cross‐sectional study was to investigate the association between MetS and periodontitis among 80‐year‐old Japanese subjects.Material and MethodsThe subjects were 234 Japanese aged 80 years old who participated in a health and periodontal examination in June 2008 in Niigata city, Japan, and were classified into three groups: (i) severe periodontitis: having six or more interproximal sites with clinical attachment level ≥ 6 mm and three or more interproximal sites with probing pocket depth (PPD) ≥ 5 mm (not on the same tooth) (n = 19); (ii) moderate periodontitis: having six or more interproximal sites with clinical attachment level ≥ 4 mm or six or more interproximal sites with PPD ≥ 5 mm (not on the same tooth) (n = 162); and (iii) no or mild periodontitis: neither “moderate” nor “severe” periodontitis (n = 53). MetS was defined using the modified criteria of the guidelines for the diagnosis of MetS in Japan. An ordinal logistic regression model was used to evaluate the association between MetS and periodontitis. Adjustments for gender, income, education, smoking status, dental visiting patterns, brushing frequency, exercise habits and dietary energy and food intake were considered.ResultsOverall, 57 individuals (24.4%) were diagnosed as having MetS. MetS was associated with the presence and severity of periodontitis (crude odds ratio = 2.24, 95% confidence interval = 1.14–4.41). This association remained statistically significant after multivariate adjustments (adjusted odds ratio = 2.10, 95% confidence interval = 1.03–4.28).ConclusionOur findings provide evidence of an association between MetS and periodontitis in elderly Japanese.
Sleep duration and history of stroke among adults from the USA
Authors: Fang Jing , Wheaton Anne G. , Ayala Carma 
Published: May 2014

SummaryAlthough short sleep duration is related to chronic conditions, such as hypertension, diabetes and obesity, the association with stroke is less well known. Using 2006–2011 National Health Interview Surveys, we assessed the association between self‐reported duration of sleep and prevalence of stroke stratifying by age and sex. Of the 154 599 participants aged 18 years or older, 29.2%, 61.8% and 9.0% reported they sleep ≤6, 7–8 and ≥9 h per day, respectively. Corresponding age‐standardized prevalence of stroke were 2.78%, 1.99% and 5.21% (P < 0.001). Logistic regression models showed a higher prevalence of stroke among those who slept ≤6 or ≥9 h a day compared with those who slept 7–8 h, after adjusting for sociodemographic, behavioural and health characteristics. Further stratifying by age and sex showed that the association of duration of sleep and stroke differed among different age or sex groups. Among young adults (18–44 years), a higher prevalence of stroke was found among women with short sleep. Higher prevalence of stroke was found among middle‐aged men and women reporting short or long sleep duration. Among older adults (≥65 years), higher prevalence of stroke was found only among those who slept ≥9 h. In this national sample of adults, the association between duration of sleep and stroke varied by sex and age. Although there was an association of short sleep duration with stroke, we also observed the association of long sleep duration with stroke, especially among those aged 65 years or older.
Inpatient resource utilization, disease severity, mortality and insurance coverage for patients hospitalized for hepatitis C virus in the United States
Authors: Younossi Z. M. , Otgonsuren M. , Henry L. , Arsalla Z. , Stepnaova M. , Mishra A. , Venkatesan C. , Hunt S. 
Published: May 2014

SummaryAlthough the incidence of new hepatitis C virus (HCV) infection has fallen, HCV‐related complications are on the rise. Our aim was to assess and describe the 2005–2009 national inpatient mortality and resource utilization trends for patients with HCV. Data from the National Inpatient Sample (NIS) and the National Hospital Discharge Survey (NHDS) between 2005 and 2009 were analyzed. Included were all adult hospital discharges with HCV‐related ICD‐9 codes. Incremental hospital charge, in‐hospital mortality and length of stay (LOS) were estimated using n = 1000 bootstrap replicates clustered by unique hospital identifier. A total of 123 939 (0.38%) discharges were related to HCV (primary or secondary diagnosis). In‐hospital mortality increased from 1.7% (2005) to 2.6% (2009) (P < 0.001). Inflation‐adjusted charges increased 2% annually from 2005 ($16 455 ± $570) to 2009 ($17 532 ± $1007, P = 0.029). This increase occurred despite the average LOS (5 days) and hospital costs ($6500) remaining stable while at the same time, hospital‐to‐hospital transfer admissions and disposition to home health care increased. HCV‐related hepatocellular carcinoma predicted longer hospital stay and death; older age predicted death; and receiving more procedures predicted higher hospital costs. The percentage of patients with private insurance significantly decreased (4.7%), while government‐sponsored insurance and uninsured increased by 2.5% and 2.1%, respectively (P < 0.05). Uninsured patients had a 49%–72% greater chance of dying during hospitalization than those with government‐sponsored insurance. HCV‐related inpatient mortality and resource utilization have increased. HCC was the largest predictor for mortality and resource utilization. These data are consistent with the rising clinical and societal burden of chronic hepatitis C in the United States.
Closing the gap between plant ecology and Quaternary palaeoecology
Authors: Reitalu Triin , Kuneš Petr , Giesecke Thomas 
Published: May 2014

AbstractEcology and Quaternary palaeoecology have largely developed as parallel disciplines. Although both pursue related questions, information exchange is often hampered by particularities of the palaeoecological data and a communication gap has been perceived between the disciplines. Based on selected topics and developments mainly in Quaternary palaeoecology, we show that both disciplines have converged somewhat during recent years, while we still see untapped potential for closer interactions. Macroecology is probably the discipline that most easily combines different time scales and where co‐operations between palaeoecologists, geneticists and vegetation modellers have been inspiring. Quantitative vegetation reconstructions provide robust estimates of tree composition and land cover at different spatial scales, suitable for testing hypotheses about long‐term vegetation changes or as quantitative background data in studies on contemporary vegetation patterns. Palaeo data also hold yet unexplored potential to study the drivers of long‐term diversity, and aspects of functional diversity may facilitate comparisons between continents and over glacial–interglacial cycles.
Successful Case of Conservative Treatment of Vesicovaginal Fistula by Hodge Pessary Insertion
Authors: PARK Soo‐Hwan , PARK Won Hee , KIM Hyeong Gon 
Published: May 2014

CaseAn 88‐year‐old woman visited us with a complaint of total urinary leak, and was diagnosed as having vesicovaginal fistula after pessary insertion. A part of pessary was seen in the bladder and it was removed by cutting pessary in the vagina. And then she was managed by antibiotics, local estrogen cream and Foley catheter indwelling.OutcomeVesicovaginal fistula was healed completely. This is the first successful case of conservative treatment of vesicovaginal fistula caused by vaginal pessary without surgical repair.ConclusionThe conservative approach could be an option of treatments of vesicovaginal fistula caused by neglected vaginal pessary.
Anesthesia for interventional radiology
Authors: Landrigan‐Ossar Mary , McClain Craig D. 
Published: May 2014

SummaryPediatric patients in the neurointerventional radiology setting pose the dual challenges of caring for relatively sick patients in the outfield environment. For safe and successful practice, the anesthesiologist must not only understand the nuances of pediatric anesthesia and the physiologic demands of the cerebral lesions. They must also help maintain a team‐based approach to safe, compassionate care of the child in this challenging setting. In this review article, we summarize key aspects of success for several of these topics.
Reducing social pain: Sex differences in the impact of physical pain relievers
Authors: VANGELISTI ANITA L. , PENNEBAKER JAMES W. , BRODY NICHOLAS , GUINN TREY D. 
Published: May 2014

AbstractThere is evidence that social pain or “hurt feelings” and physical pain share the same neural system. Although researchers have found that a physical pain reliever can reduce social pain, studies suggest that sex differences may influence these findings. Our results indicate that women who took ibuprofen felt less hurt or social pain when they were excluded from a game and when they relived a painful experience than did women who took a placebo. Men who took the pain reliever, by contrast, felt more hurt in both situations than did those who took the placebo. Further, the sex difference revealed in men's and women's ratings of their social pain was reflected in their open‐ended verbal descriptions of social and physical pain.
MRD detection of leukemia relapse using HLA typing by FACS in combination with FISH after mismatched allogeneic stem cell transplantation
Authors: Miyachi Mitsuru , Watanabe Eri , Watanabe Nobukazu , Tsuma Yusuke , Kawashima‐Goto Sachiko , Tamura Shinichi , Imamura Toshihiko , Ishida Hiroyuki , Hosoi Hajime 
Published: May 2014

AbstractLoss of mismatched HLA is a cause of relapse following HLA‐mismatched allo‐SCT. We directly detected the loss of mismatched HLA alleles in relapsed leukemic cells at a MRD level using HLA typing by multicolor FACS (HLA‐Flow) in combination with FISH in the BM of two patients with MLL‐AF9‐positive AML, at 6 and 10 months after mismatched allo‐SCT. HLA‐Flow with FISH analysis detected relapsed leukemic cells not expressing a mismatched HLA allele and harboring the MLL rearrangement. Simultaneously, real‐time quantitative RT‐PCR detected a low copy number of MLL‐AF9 transcripts, consistent with MRD detection. HLA‐Flow with FISH is a powerful method for detecting molecular relapse after mismatched allo‐SCT and provides important information on the HLA expression status of the relapsed leukemic cells to help determine the next intervention.
Acquired discrete subaortic stenosis in solid organ transplant recipients
Authors: Tsuda Takeshi , Dunn Stephen , Radtke Wolfgang 
Published: May 2014

AbstractDSS is a rare acquired abnormality of the LV outflow tract in children and adults. DSS can be seen with or without associated congenital heart disease, but the mechanism of its emergence has been poorly understood. Here, we report two cases of DSS that developed after solid organ transplant in childhood. One patient underwent liver and kidney transplant at three yr of age for hereditary polycystic disease, and the other had liver transplant at three months of age due to uncontrollable high‐output failure secondary to a large hepatic hemangioma. Both patients developed mild dynamic LV outflow tract obstruction and systemic hypertension soon after transplant, both of which resolved by the time of discharge. Transient LV hypertrophy was observed in both cases. Corticosteroids, cyclosporine A, and tacrolimus were used as initial immunosuppressants. Both patients developed DSS long after the regression of the initial dynamic LV outflow tract obstruction. Herein, we report DSS as an atypical late cardiovascular complication after solid organ transplant and postulate that transient post‐transplant hyperdynamic LV outflow tract obstruction and chronic immunosuppressive treatment may lead to subendocardial remodeling resulting in a fibromuscular membranous ridge in susceptible subjects.
Outcomes of renal transplant in patients with anti‐complement factor H antibody‐associated hemolytic uremic syndrome
Authors: Khandelwal Priyanka , Sinha Aditi , Hari Pankaj , Bansal Virinder K. , Dinda Amit K. , Bagga Arvind 
Published: May 2014

AbstractAtypical HUS associated with anti‐CFH autoantibodies is an uncommon illness associated with high risk of progression to end‐stage renal disease. Disease relapses after transplantation, observed in one‐third cases, often lead to graft loss. We report four patients with anti‐CFH antibody‐associated HUS who underwent renal transplantation 16–62 months from initial presentation. Two patients each received organs from deceased and living‐related donors. Anti‐CFH antibody titers were monitored during the illness and following transplantation. All patients received two doses of IV rituximab before or after transplantation; three patient each received 1–2 g/kg of IV immunoglobulin or underwent 2–5 sessions of plasma exchanges. The use of therapeutic plasma exchange, IV immunoglobulin, and rituximab in two cases enabled two‐third reduction in anti‐CFH antibody titers before transplantation. At 5‐ to 26‐month follow‐up, all patients showed satisfactory graft function without recurrence of HUS. This is the first report of patients with anti‐CFH antibody‐associated HUS who underwent living‐related renal transplantation. Clearance of anti‐CFH antibody by therapeutic plasma exchange and adjuvant immunosuppression aimed at decreasing antibody levels may enable successful transplantation and recurrence‐free survival.
Hepatic venous outflow obstruction in pediatric liver transplantation: Technical considerations in prevention, diagnosis, and management
Authors: Sommovilla J. , Doyle M. M. , Vachharajani N. , Saad N. , Nadler M. , Turmelle Y. P. , Weymann A. , Chapman W. C. , Lowell J. A. 
Published: May 2014

AbstractHVOO creates significant diagnostic and management dilemmas in pediatric liver transplant recipients, particularly with TVGs (split or reduced‐size grafts). Numerous technical variations for the hepatic vein to IVC anastomosis have been described to minimize the incidence of this complication, but no consensus for an optimal anastomotic technique exists. One hundred and thirty‐four liver transplants (70 TVGs) were performed in 124 patients between 1994 and 2011. These were divided into two cohorts. Group 1 (95 transplants, 41 TVGs) utilized a continuous running anastomosis. Group 2 (39 transplants, 29 TVGs) implemented a triangulated (three‐stitch) anastomosis. All were reviewed for demographics, diagnostics, interventions, and outcome. The overall HVOO incidence was seven of 134 transplants (5.2%) and six of 70 transplants utilizing TVGs (8.6%). Group 1 incidence was five of 41 (12.2%) compared with one of 29 (3.4%; p = 0.20, OR 3.89) in Group 2. Liver Doppler was employed in all patients, and only three suggested HVOO. All patients with HVOO underwent venogram, at a median of 81 days post‐transplant. All underwent percutaneous venoplasty and required 1–6 treatments, all resulting in HVOO resolution. Incidence of HVOO has improved since adopting the triangulated anastomosis, although not to a level of statistical significance. US is not adequately sensitive to exclude HVOO. Venogram is recommended in patients with prolonged ascites, and venoplasty has been highly successful in HVOO treatment.
Use of belatacept to maintain adequate early immunosuppression in calcineurin‐mediated microangiopathic hemolysis post‐renal transplant
Authors: Reynolds B. C. , Talbot D. , Baines L. , Brown A. 
Published: May 2014

AbstractWe report a 17‐yr‐old boy who developed a microangiopathic hemolytic anemia presumed secondary to tacrolimus shortly following a living‐related donor renal transplant. This was initially managed by plasmapheresis. Reinstitution of calcineurin inhibition using cyclosporine led to recurrence of hemolysis, so an alternative agent was needed. He was commenced on monthly intravenous belatacept, with no further recurrence of the hemolysis, and subsequent stable graft function. Modulation via CTLA‐4 offers an alternative immunosuppressive tactic if current regimens produce graft threatening adverse effects. The method of administration and frequency of dosage of belatacept also lends itself well to the high‐risk period of adolescence and transition. We propose that belatacept may therefore also have utility in difficult cases complicated by poor concordance, common in the adolescent age group.
A child with unresectable biliary rhabdomyosarcoma: 48‐month disease‐free survival after liver transplantation
Authors: Paganelli M. , Beaunoyer M. , Samson Y. , Dal Soglio D. , Dubois J. , Lallier M. , Alvarez F. 
Published: May 2014

AbstractWe describe here a two‐yr‐old boy with biliary RMS successfully treated by chemotherapy and LT. The child presented with obstructive jaundice at 20 months of age. A mildly vascularized, non‐calcified, partially cystic lesion was visualized in the left hepatic lobe. Solid infiltration of the common bile duct and of both left and right hepatic ducts was suspected. Liver biopsy suggested a botryoid‐type embryonal RMS originating from the biliary tract. After extrahepatic spread of the tumor was excluded, a biliary drain was applied and neoadjuvant chemotherapy was started. After the treatment, although reduced in volume, the mass was still unresectable without aggressive surgery and gross residual disease. LT with a reduced segment II/III graft was performed four months after diagnosis. The patient received six cycles of adjuvant chemotherapy, and he is alive and recurrence‐free 48 months post‐transplantation. A posteriori, the transplant might have possibly been avoided with an aggressive resection with biliary reconstruction. Nevertheless, although the risk of the transplant has to be balanced against the chemoresponsiveness of the tumor, the four‐yr disease‐free survival of this patient suggests that, when coupled with effective chemotherapy, transplantation might be considered a potential treatment for unresectable biliary RMS.
The depositional architecture and facies variability of shelf deltas in the Eocene Battfjellet Formation, Nathorst Land, Spitsbergen
Authors: Grundvåg Sten‐Andreas , Helland‐Hansen William , Johannessen Erik P. , Olsen Andreas H. , Stene Stig A. K. 
Published: May 2014

AbstractDeltas are commonly classified according to their plan‐view morphology as either river‐dominated, tide‐dominated or wave‐dominated. However, most deltas form under the mixed influence of these processes, commonly with laterally varying process regimes. It has also become clear that there is a mismatch between the plan‐view morphology and internal facies composition in some deltas. Combined outcrop and subsurface data from the Eocene Battfjellet Formation, Spitsbergen, provide an example of ancient shelf deltas that formed under mixed influence. Internally, these shelf deltas are characterized by wave‐dominated facies that are normally associated with strike‐extensive, nearly linear shoreline sandstones. However, the formation comprises partially overlapping sandstone bodies of limited lateral extent (<20 km in any direction). This stacking pattern is attributed to frequent autogenic lobe switching that caused localized and rapid transgressions. Such processes typify fluvial‐dominated deltas and occur less commonly in wave‐dominated ones. Thus, there is an apparent mismatch between inferred plan‐view morphology and internal facies composition. It is argued that the Battfjellet deltas were flood‐dominated and prograded mainly during periods of high fluvial discharge. However, reworking of the fluvial‐flood facies by fair‐weather and storm waves, as well as longshore currents, resulted in a wave‐dominated facies character. Delta lobes undergoing auto‐retreat were particularly prone to reworking by basinal processes, including tidal currents. It is suggested that repeated delta progradation from inner shelf settings towards the outer shelf and shelf edge was aided by high sediment supply rather than relative falls in sea‐level as previously suggested. This interpretation is supported by: (i) the lack of major facies dislocations and extensive sub‐aerial unconformities; and (ii) an overall relative rise in sea‐level as evidenced by an overall low‐angle (0·8 to 1·2°) ascending shoreline trajectory. The latter results from the combined effect of basin subsidence, eustatic highstand and sediment compaction.
The elliptic Weyl character formula
Authors: Ganter Nora 
Published: May 2014

AbstractWe calculate equivariant elliptic cohomology of the partial flag variety$\def \xmlpi #1{}\def \mathsfbi #1{\boldsymbol {\mathsf {#1}}}\let \le =\leqslant \let \leq =\leqslant \let \ge =\geqslant \let \geq =\geqslant \def \Pr {\mathit {Pr}}\def \Fr {\mathit {Fr}}\def \Rey {\mathit {Re}}G/H$, where$H\subseteq G$are compact connected Lie groups of equal rank. We identify the${\rm RO}(G)$-graded coefficients${\mathcal{E}} ll_G^*$as powers of Looijenga’s line bundle and prove that transfer along the map$$\begin{equation*} \pi \,{:}\,G/H\longrightarrow {\rm pt} \end{equation*}$$is calculated by the Weyl–Kac character formula. Treating ordinary cohomology,$K$-theory and elliptic cohomology in parallel, this paper organizes the theoretical framework for the elliptic Schubert calculus of [N. Ganter and A. Ram,Elliptic Schubert calculus, in preparation].
Minimal genus and fibering of canonical surfaces via disk decomposition
Authors: Stoimenow A. 
Published: May 2014

AbstractThis paper contains some applications of the description of knot diagrams by genus, and Gabai’s methods of disk decomposition. We show that there exists no genus one knot of canonical genus 2, and that canonical genus 2 fiber surfaces realize almost every Alexander polynomial only finitely many times (partially confirming a conjecture of Neuwirth).
The Freedom to Choose: Elite Female Athletes’ Preferred Representations Within Endorsement Opportunities
Authors: Fink Janet S. , Kane Mary Jo , LaVoi Nicole M. 
Published: May 2014

“I want to be respected for what I do instead of what I look like”—Janie, a swimmer“They can see the moves I make, the action I make [on the court]. But I also want them to see this is who I am off the court. I’m not just this basketball player. I can be somebody else”—Melanie, a basketball playerDespite unprecedented gains in women’s sports 40 years after Title IX, female athletes are rarely used in endorsement campaigns and, when used, are presented in sexually provocative poses versus highlighting their athletic competence. This pattern of representation continues, though empirical evidence demonstrates consumers prefer portrayals focusing on sportswomen’s skill versus their sex appeal. Research also indicates females are keenly aware of gendered expectations which create tensions between being athletic and “appropriately feminine.” The current study addresses what we don’t know: how elite female athletes wish to be portrayed if promised the same amount of financial reward and commercial exposure. Thirty-six team and individual scholarship athletes were asked to choose between portrayals of femininity and athletic competence. Findings revealed that competence was the dominant overall choice though close to 30% picked both types of portrayals. Metheny’s gendered sport typology was used to analyze how sportswomen’s preferences challenge, or conform to, traditional ideologies and practices surrounding women’s sports. Implications for sport management scholars and practitioners are discussed.