bluuebunny/crossref_metadata_2025_split huggingface dataset:
Digital Papillary Adenocarcinoma: Uncommon Malignancy of Sweat Glands - Two Rare Cases
Authors: Goyal Neeti , Dhaman Pawan , Bhatia Jasvinder Kaur , Sharma Pragya , Mishra Prabha Shankar , Singh Vikram , Rathore Anvesh 
Published: August 2024

Abstract

Background:
Digital papillary adenocarcinoma (DPA) is a very rare malignant tumor of the sweat glands originally described by Helwig in 1979.It often presents as a solitary painless mass, commonly found on the volar surface of the fingers and toes and the adjacent skin of the palms and soles.

Materials and Methods:
Two rare cases of DPA in 43- and 48-year-old male patients who presented with swelling finger were included over period of one year study in a tertiary care hospital.

Results:
Our study had two cases with male patient of age 48 year and 43 year old. Both presented with swelling and a mass lesion left middle finger, past 8 years and nodule in proximal phalangeal region of left index finger for 15 years respectively. On histomorphology and immunohistochemistry both were diagnosed as DPA.

Conclusion:
DPA is a rare adnexal tumor which generally present for months to years before the patient seeks medical attention. Careful evaluation with early surgical removal and accurate histological diagnosis is must when managing patients with DPA as these can be aggressive and even result in metastasis.
Application of Radiographic/Imaging Techniques: A Questionnaire Study Involving Private Practitioners in Malaysia
Authors: Puang Ye Weng , Suib Fatin Hanisah , Chan Bryan Hean Kean , Nambiar Phrabhakaran , Subramaniam Ratnasothy , Azmi Nuruljannah Nor , Wong Gou Rean 
Published: August 2024

Abstract

Background:
A study was carried out to get an updated overview of the applications of radiographic/imaging techniques, types of dental X-ray machines, and radiation hygiene tendencies among private dental practitioners.

Materials and Methods:
A survey was carried out to obtain an overview of the application of radiographic techniques by sending a questionnaire (Google Forms) to more than 1000 private dental practitioners in all states of Malaysia. In addition, several questionnaires were also completed by visiting many dental clinics in person.

Results:
A total of 410 responses were received. Results indicated that a majority of the practitioners owned at least an intraoral radiographic machine (90.9%). A relatively high number had panoramic machines (76.1%) and cone-beam computed tomography (CBCT) machines (42.5%). Intraoral images were acquired by private dentists at a rate of 11–20 per month (34.3%, n = 116 respondents), with only 13.6% (n = 46 respondents) acquiring more than 50 per month. With regard to panoramic and CBCT imaging, most of them took between 1 and 30 panoramic images and 1–20 CBCT scans, respectively, in a month.

Conclusion:
General dental practitioners in Malaysia are very dependent on various dental imaging techniques that can be performed in their own clinics. The demographic status indicated that most of the advanced imaging machines were owned by young practitioners as they are better exposed to these imaging modalities. Moreover, although the respondents graduated from universities in different countries, they had a high level of knowledge of radiation protection (>80%) when practicing oral and maxillofacial radiography.
Effect of walking meditation on perceived stress and mental well-being in oncology health-care professionals: A randomized controlled trial
Authors: Joshi Anjali Mangesh , Mehta Suchitra Ajay , Wadhwani Santoshi Raju 
Published: August 2024

ABSTRACT

Introduction:
Occupational stress and burnout affect the psychological well-being of oncology health-care professionals (OHCPs). This study evaluated the effects of 6 weeks of movement-based walking meditation (WM) intervention on perceived stress (PS) and mental well-being (MWB) in OHCPs working at a tertiary care super specialty oncology hospital in central India.

Materials and Methods:

n = 62 OHCPs were randomly assigned to the intervention (n = 32) or the control group (n = 30). The PS Scale and Warwick-Edinburgh Mental Well-being Scale were used for assessments at the baseline and after 6 weeks. The intervention group practiced 20 min of WM daily, with moment-to-moment awareness of the physical sensations, thoughts, and emotions during walking. The control group did not receive any intervention.

Results:

n = 53 participants (n = 25 in the intervention and n = 28 in the control group) were included in the analysis. At the end of 6 weeks, the control group showed a significant increase in PS (p < 0.001, Cohen’s d = 3.38) and a decline in MWB (p < 0.001, Cohen’s d = 6.46). In the intervention group, a comparison of pre–post scores demonstrated a significant reduction in PS (p < 0.001, Cohen’s d = 3.23) and improvement in MWB (p < 0.001, Cohen’s d = 5.26). The group comparison of postscores indicated a significant reduction in PS (p < 0.001, Cohen’s d = 4.43) and improvement in MWB (p < 0.001, Cohen’s d = 8.41) in the intervention group as compared to the control group. No unanticipated adverse events were observed.

Conclusion:
The results highlight the efficacy of a life-based WM intervention to address the mental health challenges of OHCPs. Further validation is required to draw definitive conclusions.
cNPAS2 induced β cell dysfunction by regulating KANK1 expression in type 2 diabetes
Authors: Yin Yan-Bin , Ji Wei , Liu Ying-Lan , Gao Qian-Hao , He Dong-Dong , Xu Shi-Lin , Fan Jing-Xin , Zhang Li-Hai 
Published: August 2024

BACKGROUND
Diabetes mellitus type 2 (T2DM) is formed by defective insulin secretion with the addition of peripheral tissue resistance of insulin action. It has been affecting over 400 million people all over the world.
AIM
To explore the pathogenesis of T2DM and to develop and implement new prevention and treatment strategies for T2DM.
METHODS
Receiver operating characteristic (ROC) curve analysis was used to conduct diagnostic markers. The expression level of genes was determined by reverse transcription-PCR as well as Western blot. Cell proliferation assays were performed by cell counting kit-8 (CCK-8) tests. At last, T2DM mice underwent Roux-en-Y gastric bypass surgery.
RESULTS
We found that NPAS2 was significantly up-regulated in islet β cell apoptosis of T2DM. The ROC curve revealed that NPAS2 was capable of accurately diagnosing T2DM. NPAS2 overexpression did increase the level of KANK1 . In addition, the CCK-8 test revealed knocking down NPAS2 and KANK1 increased the proliferation of MIN6 cells. At last, we found that gastric bypass may treat type 2 diabetes by down-regulating NPAS2 and KANK1 .
CONCLUSION
This study demonstrated that NPAS2 induced β cell dysfunction by regulating KANK1 expression in type 2 diabetes, and it may be an underlying therapy target of T2DM.
PROPAGATION IMPAIRMENTS IN 6G COMMUNICATION DUE TO NON-LINE OF SIGHT EFFECTS
Authors: Enoch Sharmini 
Published: August 2024

The emerging sixth-generation (6G) mobile network provides a higher spectrum to users. It uses frequencies between 7 GHz and 3 THz. In such frequencies the effects of propagation impairments on the signal are significant. The present work is focused on analyzing the effects of the environmental factors lying in the line of Sight (NLOS) path between the transmitter and the receiver. At frequencies above 7 GHz, the link operates under dense urban areas having high-rise buildings, rural areas or mountainous terrain having tall trees, etc. Hence in an NLOS link, the effects of shadowing, vegetation, and multipath fading are significant. A system undergoes multipath propagation when multiple reflections of the transmitting signal arrive at the receiver at different times. The empirical models are used for this analysis, to estimate the losses due to diffraction, vegetation, and shadowing. This study is useful in the design of a 6G system taking into consideration the signal impairments.
Pandangan Tokoh Falak tentang Elongasi pada Penentuan Awal Syawal 1443 H dalam Kriteria Neo MABIMS di Indonesia
Authors: Aini Nur , Azkarrula Youla Afifah 
Published: August 2024

Indonesia implemented the Neo MABIMS criteria for the first time at the beginning of Ramadan and Shawwal 1443 H/2021 AD. However, the application of this new criterion raises an issue of problems in determining the beginning of Shawwal 1443 H. This problem arises in the implementation of the elongation parameter. So there is a confusion that arises for experts and observers of falak in the case of the beginning of the month. This will lead to uncertainty if it is not studied. Therefore, this research was raised using field research and qualitative approach. Data collection in this study was carried out by interviewing Indonesian Falak figures and some data using documentation. The data obtained were analyzed using descriptive analysis method and triangulation method to obtain valid results. The results of this study indicate that the Neo MABIMS criteria are the result of a new agreement from the renewal of previous criteria with higher parameters. The problem in determining the beginning of Shawwal 1443 H by implementing the Neo MABIMS criteria arises due to the lack of agreement on the use of geocentric or topocentric elongation parameters. In this Shawwal case, the experts decided to use geocentric elongation by considering maslaha (public interest). However, for this case, it was still in an ambiguous state due to there were two paradigms from the Falak figures regarding the implement of elongation, namely geocentric and topocentric.
IMPACT OF NUTRIENT-SPECIFIC MODULATION ON COLD STRESS TOLERANCE: INSIGHTS FROM Drosophila ananassae AND D. bipectinata
Authors: G Appaji Nishkala , B P Harini 
Published: August 2024

Drosophila species (fruit flies) have long served as valuable model organisms in evolutionary research. Among the diverse traits exhibited by fruit flies, cold tolerance stands out as a critical factor influencing their ecological distribution and survival in varied environments. The majority of research on cold tolerance concentrates on subjecting flies to a single, stressful temperature without any modulation in the diet. The present study aimed to understand the impact of nutrient-specific modulation on the cold tolerance of Drosophila ananassae and D. bipectinata across a broad range of lower temperatures. Adult flies were transferred to the media composition enriched with sucrose and tryptophan in three replicates and maintained at 22oC. 20 flies of a particular stage: adults, eggs, larvae and pupa were exposed to 18oC, 14oC, and 10oC for 5 days. The impact of cold stress on their growth and survival was noted for 5 following days. The impact of dietary modifications on cold stress tolerance and life history traits was positive and consistent across both species. In contrast, D. bipectinata had greater survival rates than D. ananassae across all temperatures and dietary regimes. Tryptophan (100 mg) diet performed best to improve life traits on cold stress treatment.
Life-Cycle Estimates of Earnings Growth by Education and Gender
Authors: Even William E. , Macpherson David A. 
Published: August 2024

Abstract
This paper updates and refines the estimates of age-earnings profiles provided in William E. Even and David A. Macpherson (2018). Relative to the earlier work, the estimates provided here use more recent data, improve the controls for the impact of the labor market on earnings, and provide both sex-specific and sex-neutral estimates of age-earnings profiles by education.
Attitudes, practices and perceived barriers toward implementing non-pharmacological management for rheumatoid arthritis among rheumatologists: an online cross-sectional survey
Authors: Kronbi Fatine , Rkain Hanan , Ez-zaoui Samya , Benzine Nada , Abouqal Redouane , Belayachi Jihane , Hajjaj-Hassouni Najia , Tahiri Latifa , Allali Fadoua 
Published: August 2024

ObjectivesOur study aimed to evaluate the integration level of non-pharmacological mana­gement (NPM) for rheumatoid arthritis (RA), analyze attitudes, practices, and perceived barriers towards NPM implementation, and identify factors contributing to the underutilization of non-
pharmacological treatment in RA.Material and methodsA descriptive and analytical cross-sectional study was conducted among rheumatologists in Morocco. Rheumatologists received an online questionnaire gathering sociodemographic data, NPM integration level for RA, exploring their attitudes, practices and perceived barriers regarding the integration of NPM for RA, using a Likert scale ranging from 1 to 5. Univariate analyses were conducted to identify risk factors for under-integration of NPM for RA.ResultsOut of 440 questionnaires sent, 132 rheumatologists responded to the survey (mean age of 44 ±12 years, 112 (84.8%) females, median professional experience of 15 years [4.7; 26.3]) with a response rate of 30%. All rheumatologists agreed on the importance of NPM integration into their practice with 130 (98.5%) supporting the necessity of tailored recommendations of NPM of RA for the Moroccan context. Sixty-nine (52.3%) reported a lack of NPM integration for RA. Only 36 (27.3%) consistently provided personalized NPM from RA diagnosis and 47 (35.6%) involved patients in
decision-making. Comment perceived barriers included difficulties in organizing multidisciplinary care (122; 92.4%), difficulties with time management in consultation (119; 90.2%), and lack of multi­disciplinary team members (116; 87.9%). In univariate analysis, lack of suitable training and lack of knowledge on NPM of RA were risk factors of under-integration of NPM of RA with respectively an odds ratio (OR) of 0.09, 95% CI: 0.01–0.86 and OR of 0.34, 95% CI: 0.15–0.76.ConclusionsOur study revealed significant insufficiencies in the integration of NPM of RA among Moroccan rheumatologists. Perceived barriers, including insufficient training, lack of knowledge, and infrastructural limitations, hinder effective implementation. Addressing these through tailored education and multidisciplinary collaboration is essential for improving RA management.
Evaluation of the Organoleptic Properties of Calabash Fruit (Crescentia Cujete) Jam: A Comprehensive Sensory analysis
Authors: Jorene Mae J. Tagud  , Minerva B. Baclayon  , Jose C. Agoylo Jr.  
Published: August 2024

Abstract: This study was conducted to formulate a Calabash fruit jam and evaluate the developed product's sensory characteristics and consumer acceptability. A 2k factorial design was used to measure224 g calabash pulp and sugar levels. There was no significant difference in the sensory attributes across different treatments in terms of color, aroma, and flavor. However, the Friedman test showed that there was a difference in the sensory characteristics across different treatments in terms of texture. Results reveal that Treatments 1 with -125 g. level of pulp and sugar, Treatment 3 with -125 g. and +224 g. levels of pulp and sugar and Treatment 4 with +224 g. levels of pulp and sugar have the same texture and Treatment 2 with +224 g. and -125 g. level of pulp and sugar is different from these three treatments. In terms of sensory acceptability, there was a significant difference in the sensory acceptability across other treatments in terms of texture, aroma, color, and flavor. Further, results reveal that Treatment 1 with -125 g. level of pulp and sugar, Treatment 3 with -125 g. and +224 g. levels of pulp and sugar and Treatment 4 with +224 g. levels of pulp and sugar have the same texture, aroma, color, and flavor, and Treatment 2 with +224 g. and -125 g. level of pulp and sugar is different from these treatments. Hence, considering the production cost of each treatment, the lowest production cost was considered, and Treatment 1 with -125 g. level of pulp and sugar got the lowest production cost among other treatments.
PENGOLAAN IKAN BARAKUDA (FIOURSE FOOD) SEBAGAI MAKANAN SEHAT DAN PENGEMBANGAN UMKM DI DESA PESISIR
Authors: Wafa Hosnol , Yunus Eko Yudianto , Shodieqy Ahmed Fatahillah , Holilur R.E Achmad 
Published: August 2024

Aset laut tepatnya di Desa Pesisir sangat melimpah, masyarakat di desa tersebut sangat memanfaatkan hasil laut tersebut, oleh karena itu masyarakat di Desa Pesisir hampir seluruh warganya berpenghasilan dari hasil laut tersebut. Tapi sayangnya, masyarakat di Desa Pesisir tidak mengetahui bagaimana mengelolah hasil laut agar menjadi sesuatu yang lebih daripada mereka hanya menjual hasil laut secara langsung tanpa di kelola menjadi makanan yang sehat dan bernilai tinggi. Untuk mengatasi permasalahan tersebut, Mahasiswa Universitas Panca Marga Probolinggo yang sedang melakukan Kuliah Kerja Nyata (KKN) yang bertempat di Desa Pesisir merencanakan untuk melakukan kegiatan program unggulan yaitu “Pengelolaan Ikan Barakuda (Fiourse Food) Sebagai makanan Sehat Dan Pengembangan UMKM” Kegiatan tersebut bertujuan untuk mempermudah warga untuk mengelola hasil laut dengan nilai yang tinggi. Kegiatan pengabdian masyarakat ini dimulai dengan riset kepada warga sekitar bahwa ikan yang paling banyak ditemui adalah ikan barakuda yang dimana ikan tersebut sangat mudah didapatkan oleh beberapa nelayan atau warga pesisir itu sendiri. Dengan ide ini kami ingin mengembangkan UMKM masyarakat Desa Pesisir untuk lebih bisa membuat suatu produk yang bernilai tinggi untuk dijadikan sebagai penghasilan warga di Desa Pesisir tersebut. Mahasiswa Kuliah Kerja Nyata Universitas Panca Marga Probolinggo yang tepatnya di Desa Pesisir ingin melakukan kegiatan pengabdian masyarakat dengan pengelolaan hasil laut yang bernilai tinggi bagi masyarakat di Desa Pesisir. Langkah pertama yang kami lakukan adalah mencari informasi tentang ikan barakuda dan mencari tau bagaimana masyarakat mencari ikan barakuda tersebut. Setelah itu kami melakukan survey untuk memastikan pencarian ikan barakuda tersebut bersama warga, lalu kemudian kami mencari ide untuk bagaimana ikan tersebut dikelola agar menjadi sesuatu yang bernilai tinggi. Setelah kami menemukan ide bagaimana ikan tersebut dikelola, kami mencoba untuk konsultasi dengan juru masak yang cukup ahli di Kota Probolinggo dan belajar bagaimana ikan tersebut dikelola menjadi makanan sehat dan bernilai tinggi.
Kata Kunci : Pengelolaan hasil laut, Ikan Barakuda, Desa Pesisir.
Mechanistic insight into the kinetic fragmentation of norpinonic acid in the gas phase: an experimental and density functional theory (DFT) study
Authors: Kurzydym Izabela , Błaziak Agata , Podgórniak Kinga , Kułacz Karol , Błaziak Kacper 
Published: August 2024

Abstract. Norpinonic acid has been known as an important α-pinene atmospheric secondary organic aerosol (SOA) component. It is formed in the reaction of α-pinene, β-pinene or verbenone with atmospheric oxidizing reagents. In the presented study, tandem mass spectrometry techniques were used to determine the exact norpinonic acid fragmentation pathway in the gas phase. The precursor anion – deprotonated norpinonic acid (m/z 169), generated in an electrospray (ESI) source – was introduced into the collision cell of the mass spectrometer and fragmented using the energy-resolved collision-induced dissociation (ER-CID) technique. The experimental energy values of degradation processes were determined via analysis of the breakdown curves. Quantum chemical calculations of the reaction models were also constructed, including calculation of all transition states. Comparison between the experimental and the theoretical threshold energies calculated at a ωB97XD/6-311+G(2d,p) theoretical level has shown a good correlation. Two basic pathways of the fragmentation of the parent anion [M-H]− (m/z 169) were observed. Firstly this leads to the decarboxylation product (m/z 125) and secondly to the loss of a neutral molecule (C4H6O), together with the formation of the anion m/z 99. On the other hand, the breakdown of the anion m/z 125 gives rise to the m/z 69, 57 and 55 ions. To confirm structures formed during ER-CID experiments, the gas-phase proton transfer reactions were examined of all norpinonic acid anionic fragments with a series of neutral reagents, characterized by proton affinity (PA) values. Based on PA difference analysis, the most possible chemical structures were proposed for the observed fragment anions.
Generation of global 1 km all-weather instantaneous and daily mean land surface temperatures from MODIS data
Authors: Li Bing , Liang Shunlin , Ma Han , Dong Guanpeng , Liu Xiaobang , He Tao , Zhang Yufang 
Published: August 2024

Abstract. Land surface temperature (LST) serves as a crucial variable in characterizing climatological, agricultural, ecological, and hydrological processes. Thermal infrared (TIR) remote sensing provides high temporal and spatial resolutions for obtaining LST information. Nevertheless, TIR-based satellite LST products frequently exhibit missing values due to cloud interference. Prior research on estimating all-weather instantaneous LST has predominantly concentrated on regional or continental scales. This study involved generating a global all-weather instantaneous and daily mean LST product spanning from 2000 to 2020 using XGBoost. Multisource data, including Moderate-Resolution Imaging Spectroradiometer (MODIS) top-of-atmosphere (TOA) observations, surface radiation products, and reanalysis data, were employed. Validation using an independent dataset of 77 individual stations demonstrated the high accuracy of our products, yielding root mean squared errors (RMSEs) of 2.787 K (instantaneous) and 2.175 K (daily). The RMSE for clear-sky conditions was 2.614 K for the instantaneous product, which is slightly lower than the cloudy-sky RMSE of 2.931 K. Our instantaneous and daily mean LST products exhibit higher accuracy compared to the MODIS official LST product (instantaneous RMSE = 3.583 K; daily 3.105 K) and the land component of the fifth generation of the European ReAnalysis (ERA5-Land) LST product (instantaneous RMSE = 4.048 K; daily 2.988 K). Significant improvements are observed in our LST product, notably at high latitudes, compared to the official MODIS LST product. The LST dataset from 2000 to 2020 at the monthly scale, the daily mean LST on the first day of 2010 can be freely downloaded from https://doi.org/10.5281/zenodo.4292068 (Li et al., 2024), and the complete product will be available at https://glass-product.bnu.edu.cn/ (last access: 22 August 2024).
Deep-learning-driven simulations of boundary layer clouds over the Southern Great Plains
Authors: Su Tianning , Zhang Yunyan 
Published: August 2024

Abstract. Based on long-term observations at the Southern Great Plains site by the Atmospheric Radiation Measurement (ARM) program for training and validation, a deep-learning model is developed to simulate the daytime evolution of boundary layer clouds (BLCs) from the perspective of land–atmosphere coupling. The model takes ARM measurements (including early-morning soundings and diurnally varying surface meteorological conditions and heat fluxes) as inputs and predicts hourly estimates (including cloud occurrence, the positions of cloud boundaries, and the vertical profile of the cloud fraction) as outputs. The deep-learning model offers good agreement with the observed cloud fields, especially in the accuracy with which cloud occurrence and base height are reproduced. When the inputs are substituted by reanalysis data from ERA5 and MERRA-2, the outputs of the deep-learning model provide a better agreement with observation than the cloud fields extracted from ERA5 and MERRA-2 themselves. Thus, the deep-learning model shows great potential to serve as a diagnostic tool for the performance of physics-based models in simulating stratiform and cumulus clouds. By quantifying biases in clouds and attributing them to the simulated atmospheric state variables versus the model-parameterized cloud processes, this observation-based deep-learning model may offer insights into the directions needed to improve the simulation of BLCs in physics-based models for weather forecasting and climate prediction.