bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Reactivity of Terminal Phenylpentenes in a Ruthenium‐Catalyzed Cross‐Metathesis Reaction: Construction of Linear Bifunctional C‐8 Alkenes.
Authors: Stefane Bogdan , Pozgan Franc 
Published: July 2013

AbstractThe behavior of phenylpentenes in the presence of Hoveyda—Grubbs second generation catalyst is studied.
ChemInform Abstract: Asymmetric Transfer Hydrogenation of 1‐Naphthyl Ketones by an ansa‐Ru(II) Complex of a DPEN‐SO2N(Me)‐(CH2)2 (η6‐p‐Tol) Combined Ligand.
Authors: Kisic Andrea , Stephan Michel , Mohar Barbara 
Published: July 2013

AbstractThe catalyst is generated in situ from the corresponding shelf‐stable chlorido Ru(II) dimer.
ChemInform Abstract: Synthesis of Indene Frameworks via Rhodium‐Catalyzed Cascade Cyclization of Aromatic Ketone and Unsaturated Carbonyl Compounds.
Authors: Shi Xian‐Ying , Li Chao‐Jun 
Published: July 2013

AbstractA novel Rh(III)‐catalyzed direct functionalization of the ortho‐C—H bond of aromatic ketones followed by an intramolecular cyclization gives indene derivatives in moderate to good yields.
ChemInform Abstract: Enantioselective Synthesis of Unsymmetrical Diaryl‐Substituted Spirocyclohexanonepyrazolones Through a Cascade [4 + 2] Double Michael Addition.
Authors: Zhang Jin‐Xin , Li Nai‐Kai , Liu Zhao‐Min , Huang Xiao‐Fei , Geng Zhi‐Cong , Wang Xing‐Wang 
Published: July 2013

AbstractThe reaction requires an aromatic α,β‐unsaturated ketone and an aromatic substituent at the alkenic side chain of the pyrazolone.
ChemInform Abstract: Indium Chloride Mediated Chlorolactonization: Construction of Chlorinated Lactone Fragments.
Authors: Abe Hideki , Fukazawa Naoki , Kobayashi Toyoharu , Ito Hisanaka 
Published: July 2013

AbstractThe synthetic application of the new title methodology is demonstrated on the construction of the compound (XX) possessing the framework of norsesquiterpenoid paralemnolin A (XXI).
ChemInform Abstract: Broensted Acid Catalyzed Asymmetric SN2‐Type O‐Alkylations.
Authors: Coric Ilija , Kim Ji Hye , Vlaar Tjoestil , Patil Mahendra , Thiel Walter , List Benjamin 
Published: July 2013

AbstractRacemic benzylic ethers undergo intramolecular SN2‐type alkylation in the presence of a TRIP phosphoric acid catalyst to give tetrahydrofuran derivatives with excellent enantioselectivity.
ChemInform Abstract: Tandem Nucleophilic Addition‐Intramolecular Oxa‐Michael Reaction: Novel Synthetic Route to Trifluoromethylated Phthalans.
Authors: Yuan Hongling , Gong Yuefa 
Published: July 2013

AbstractA wide range of trifluoromethylated phthalans (III) is synthesized under mild reaction conditions.
ChemInform Abstract: A New Pyrrole Synthesis via Silver(I)‐Catalyzed Cycloaddition of Vinylogous Diazoester and Nitrile.
Authors: Billedeau Roland J. , Klein Klara R. , Kaplan Daniel , Lou Yan 
Published: July 2013

AbstractA new synthesis of di‐ and trisubstituted pyrroles is achieved by treating vinylogous diazoesters and readily available nitriles with a catalytic amount of silver(I) antimony hexafluoride.
ChemInform Abstract: Enantioselective Synthesis of 3‐Substituted Tryptamines as Core Components of Central Nervous System Drugs and Indole Natural Products.
Authors: Hanessian Stephen , Stoffman Elia J. L. 
Published: July 2013

AbstractThe reaction of indole (I) with unsaturated aldehyde (II) in the presence of MacMillan′s catalyst leads to 3‐substituted indole adduct (III), which is readily converted into late‐stage intermediate (VI) of migraine drug prototype NXN274.
ChemInform Abstract: Palladium‐Catalyzed Direct Denitrogenative C‐3‐Arylation of 1H‐Indoles with Arylhydrazines Using Air as the Oxidant.
Authors: Chen Yongxin , Guo Shuaibo , Li Kangning , Qu Jinpeng , Yuan Hua , Hua Qiuru , Chen Baohua 
Published: July 2013

AbstractThe reaction can be scaled up.
ChemInform Abstract: Extending the Versatility of the Hemetsberger—Knittel Indole Synthesis Through Microwave and Flow Chemistry.
Authors: Ranasinghe Nadeesha , Jones Graham B. 
Published: July 2013

AbstractA wide range of substituted and unsubstituted indoles and heterocyclic variants are obtained by microwave mediated Hemetsberger—Knittel cyclizations and tandem cyclization‐decarboxylation.
ChemInform Abstract: Synthesis of Substituted 6‐Amino‐4‐(2,4‐dimethoxyphenyl)‐[1,2]dithiolo[4,3‐b]pyrrol‐5‐ones and Their Raising Leukocyte Count Activities.
Authors: Tan Xiangduan , Li Chungang , Yu Zhenpeng , Wang Panfeng , Nian Siyun , Deng Yifang , Wu Wei , Wang Guoping 
Published: July 2013

AbstractA series of new title compounds (XIII), (XVI), (XVII) is synthesized.
ChemInform Abstract: Synthesis of Internal Alkynes Through the Pd‐Catalyzed Coupling of Heteroaryl Halides with Terminal Alkynes.
Authors: Lu Linhua , Yan Hong , Sun Peng , Zhu Yan , Yang Hailong , Liu Defu , Rong Guangwei , Mao Jincheng 
Published: July 2013

Abstract3‐Bromo‐indole and 2‐bromo‐benzimidazole don′t give any traceable coupling products due to the occurrence of multiple side reactions as indicated by TLC.
ChemInform Abstract: Syntheses and anti‐Allergic Activity of 2‐((Bis(trimethylsilyl)methylthio/methylsulfonyl)methyl) ‐5‐aryl‐1,3,4‐oxadiazoles.
Authors: Guda Dinneswara Reddy , Park Sae‐Jin , Lee Min‐Woo , Kim Tack‐Joong , Lee Myong Euy 
Published: July 2013

AbstractConveniently obtained sila‐substituted 1,3,4‐oxadiazoles (VI) and (VII) show variable extent of antiallergic activity.
ChemInform Abstract: Use of a Semihollow‐Shaped Triethynylphosphane Ligand for Efficient Formation of Six‐ and Seven‐Membered Ring Ethers Through Gold(I)‐Catalyzed Cyclization of Hydroxy‐Tethered Propargylic Esters.
Authors: Ito Hideto , Harada Ayumi , Ohmiya Hirohisa , Sawamura Masaya 
Published: July 2013

AbstractVarious primary, secondary and tertiary alcohol substrates are tolerated.
ChemInform Abstract: Palladium‐Mediated Cyclization of 8‐Allyl‐7‐hydroxy‐2‐styrylchromones Towards the Synthesis of 7,8‐Furano‐2‐styrylchromones.
Authors: Rao C. Srinivas , Jyotsna C. , Sait Shakil S. 
Published: July 2013

AbstractThe title compounds (II) are obtained by a general, rapid, and efficient oxidation of 2‐styrylchromones (I) with dichlorobis(benzonitrile)palladium.
ChemInform Abstract: Gold‐Catalyzed Annulation of 2‐Alkynyl Benzaldehydes with Vinyl Ethers: Synthesis of Dihydronaphthalene, Isochromene, and Bicyclo[2.2.2]octane Derivatives.
Authors: Malhotra Deepika , Liu Le‐Ping , Mashuta Mark S. , Hammond G. B. 
Published: July 2013

AbstractVarious mechanisms of the very mild reactions of acyclic and cyclic vinyl ethers are discussed.
ChemInform Abstract: Palladium‐Catalyzed Picolinamide‐Directed Alkylation of Unactivated C(sp3)—H Bonds with Alkyl Iodides.
Authors: Zhang Shu‐Yu , He Gang , Nack William A. , Zhao Yingsheng , Li Qiong , Chen Gong 
Published: July 2013

AbstractAn efficient method for the alkylation of γ‐C(sp3)—H and δ‐C(sp2)—H bonds of picolinamide‐protected amine substrates with primary alkyl iodides is developed.
ChemInform Abstract: Synthesis, Structure, and Biological Activity of Novel Heterocyclic Sulfonyl‐Carboximidamides.
Authors: Gobis Katarzyna , Foks Henryk , Slawinski Jaroslaw , Sikorski Artur , Trzybinski Damian , Augustynowicz‐Kopec Ewa , Napiorkowska Agnieszka , Bojanowski Krzysztof 
Published: July 2013

AbstractTitle compounds [(III) and (V)] are synthesized by condensation of sulfonamide (II) with from nitriles (I) in situ generated or directly added carbamidates (IV), respectively.
ChemInform Abstract: A Simple and Convenient Synthesis of Tautomeric (6 or 2)‐Hydroxy‐4‐methyl‐(2 or 6)‐oxo‐1‐(substituted phenyl)‐(1,2 or 1,6)‐dihydropyridine‐3‐carbonitriles.
Authors: Ajaj Ismail , Mijin Dusan , Maslak Veselin , Brkovic Danijela , Milcic Milos , Todorovic Nina , Marinkovic Aleksandar 
Published: July 2013

AbstractTitle compounds (III) are synthesized conveniently.
ChemInform Abstract: Spirocyclic Compounds, Potent CCR1 Antagonists.
Authors: Hossain Nafizal , Ivanova Svetlana , Bergare Jonas , Eriksson Tomas 
Published: July 2013

AbstractDesign and synthesis of a novel class of spirocyclic CCR1 antagonists with sub‐nanomolar potency and excellent in vitro metabolic stability are described.
ChemInform Abstract: Copper‐Catalyzed Aerobic Oxidative C—H and C—C Functionalization of 1‐[2‐(Arylamino)aryl]ethanones Leading to Acridone Derivatives.
Authors: Yu Jipan , Yang Haijun , Jiang Yuyang , Fu Hua 
Published: July 2013

AbstractThe new protocol uses an inexpensive catalyst and an economical and environmentally friendly oxidant.
ChemInform Abstract: β‐Nitroacrylates as Key Building Blocks for the Synthesis of Alkyl 3‐Substituted 5‐Oxopiperazine‐2‐carboxylates under Fully Heterogeneous Conditions.
Authors: Gabrielli Serena , Ballini Roberto , Palmieri Alessandro 
Published: July 2013

AbstractUsing β‐nitroacrylates as key starting materials, a series of alkyl 3‐substituted 5‐oxopiperazine‐2‐carboxylates is easily prepared.
ChemInform Abstract: Synthesis and Biological Activity of Substituted 4H‐1,4‐Benzothiazines, Their Sulfones, and Ribofuranosides.
Authors: Goyal Kshamta , Gautam Naveen , Khandelwal Nishidha , Gautam D. C. 
Published: July 2013

AbstractCompounds (III), (IV), (VI), (IX), and (X) show mixed radical scavenging activity, while benzothiazine dioxides (IV) and (X) exhibit excellent activity against four bacteria strains as well as against four strains of fungi.
ChemInform Abstract: Catalytic Enantioselective Allyl—Allyl Cross‐Coupling with a Borylated Allylboronate.
Authors: Le Hai , Kyne Robert E. , Brozek Laura A. , Morken James P. 
Published: July 2013

AbstractHighly enantioselective cross‐coupling reactions between the borylated allylboronate (I) and various allylic chlorides are described.
ChemInform Abstract: Iron‐Catalyzed, Atom‐Economical, Chemo‐ and Regioselective Alkene Hydroboration with Pinacolborane.
Authors: Zhang Lei , Peng Dongjie , Leng Xuebing , Huang Zheng 
Published: July 2013

AbstractThe iron pincer complex (IPC) is found to be optimal as precatalyst in the transformation of various alkenes.
ChemInform Abstract: Nickel(II)‐Magnesium‐Catalyzed Cross‐Coupling of 1,1‐Dibromo‐1‐alkenes with Diphenylphosphine Oxide: One‐Pot Synthesis of (E)‐1‐Alkenylphosphine Oxides or Bisphosphine Oxides.
Authors: Liu Liu , Wang Yulei , Zeng Zhiping , Xu Pengxiang , Gao Yuxing , Yin Yingwu , Zhao Yufen 
Published: July 2013

AbstractMechanistic studies discover that the reaction might involve a Hirao reduction, cross‐coupling and Michael addition.
ChemInform Abstract: Synthesis of Glycosyl Cyanamides from Azides: Application for the Synthesis of N‐Hydroxyguanidinoglycosides.
Authors: Prabhu Girish , Sureshbabu Vommina V. 
Published: July 2013

AbstractThe method for the synthesis of the title compounds is simple, mild and involves primary and secondary azides of a wide range of monosaccharides and disaccharides.
ChemInform Abstract: Antiinflammatory and Antidiabetic Naphthaquinones from an Endophytic Fungus Dendryphion nanum (Nees) S. Hughes.
Authors: Mishra P. D. , Verekar S. A. , Kulkarni‐Almeida A. , Roy S. K. , Jain S. , Balakrishnan A. , Vishwakarma R. , Deshmukh S. K. 
Published: July 2013

AbstractIsolation and structure determination of two naphthoquinones, herbarin (I) and herbaridine A (II), are described.
ChemInform Abstract: Propanephosphonic Acid Anhydride (T3P®) — A Benign Reagent for Diverse Applications Inclusive of Large‐Scale Synthesis
Authors: Basavaprabhu Basavaprabhu , Vishwanatha T. M. , Panguluri Nageswara Rao , Sureshbabu Vommina V. 
Published: July 2013

AbstractReview: ca. 100 refs.
Study of Solubility Efficiency of Polycyclic Aromatic Hydrocarbons in Single Surfactant Systems
Authors: Lakra Jyotsna , Tikariha Deepti , Yadav Toshikee , Satnami Manmohan L. , Ghosh Kallol K. 
Published: July 2013

AbstractWater solubility enhancements of two polycyclic aromatic hydrocarbons i.e., naphthalene (Naph) and anthracene (Anth) in single surfactants system have been measured by UV–VIS‐Spectrophotometer. The relationships between solubilizing capacity and their solubilization efficiency towards polycyclic aromatic hydrocarbons (PAH) have been quantified and discussed in terms of the molar solubilization ratio (MSR), the micelle‐water partition coefficient (Km) and standard free energy of solubilization (ΔG°s). The micellar and surface properties of some cationic and anionic surfactants have been investigated by conductivity, surface tension and fluorescence measurements at 300 K. Above the CMC, maximum solubilization occurs in cationic surfactants where as the solubilization is least in the presence of anionic surfactants. The negative value of ΔG°s shows spontaneity of the solubilization process. The MSR values are larger in naphthalene than anthracene (Naph > Anth). The present studies provide valuable information for the selection of surfactants for solubilizing water‐insoluble compounds.
Life Shocks and Homelessness
Authors: Curtis Marah A. , Corman Hope , Noonan Kelly , Reichman Nancy E. 
Published: July 2013

AbstractWe exploited an exogenous health shock—namely, the birth of a child with a severe health condition—to investigate the effect of a life shock on homelessness in large cities in the United States as well as the interactive effects of the shock with housing market characteristics. We considered a traditional measure of homelessness, two measures of housing instability thought to be precursors to homelessness, and a combined measure that approximates the broadened conceptualization of homelessness under the 2009 Homeless Emergency Assistance and Rapid Transition to Housing Act (2010). We found that the shock substantially increases the likelihood of family homelessness, particularly in cities with high housing costs. The findings are consistent with the economic theory of homelessness, which posits that homelessness results from a conjunction of adverse circumstances in which housing markets and individual characteristics collide.
Reduced 25‐hydroxyvitamin D and risk of Alzheimer's disease and vascular dementia
Authors: Afzal Shoaib , Bojesen Stig E. , Nordestgaard B⊘rge G. 
Published: July 2013

AbstractBackgroundVitamin D deficiency has been implicated as a risk factor for dementia in several cross‐sectional studies. We tested the hypothesis that reduced plasma 25‐hydroxyvitamin D (25[OH]D) is associated with increased risk of Alzheimer's disease (AD) and vascular dementia in the general population.MethodsWe measured baseline plasma 25(OH)D in 10,186 white individuals from the Danish general population.ResultsDuring 30 years of follow‐up, 418 participants developed AD and 92 developed vascular dementia. Multivariable adjusted hazard ratios for AD were 1.25 (95% confidence interval [CI], 0.95–1.64) for 25(OH)D less than 25 nmol/L vs. greater than or equal to 50 nmol/L, and 1.29 (95% CI, 1.01–1.66) for less than the 25th seasonally adjusted 25(OH)D percentile vs. more than the 50th seasonally adjusted 25(OH)D percentile. Multivariable adjusted hazard ratios for vascular dementia were 1.22 (95% CI, 0.77–1.91) for 25(OH)D less than 50 nmol/L vs. greater than or equal to 50 nmol/L, and 1.22 (95% CI, 0.79–1.87) for less than or equal to the 50th vs. more than the 50th seasonally adjusted 25(OH)D percentile. Last, multivariable adjusted hazard ratios for the combined end point were 1.28 (95% CI, 1.00–1.64) for 25(OH)D less than 25 nmol/L vs. greater than or equal to 50 nmol/L, and 1.27 (95% CI, 1.01–1.60) for less than the 25th vs. more than the 50th seasonally adjusted 25(OH)D.ConclusionsWe observed an association of reduced plasma 25(OH)D with increased risk of the combined end point of AD and vascular dementia in this prospective cohort study of the general population.
Selection at ultra-low density identifies plants escaping virus infection and leads towards high-performing lentil (Lens culinarisL.) varieties
Authors: KARGIOTIDOU A. , CHATZIVASSILIOU E. , TZANTARMAS C. , SINAPIDOU E. , PAPAGEORGIOU A. , SKARACIS G. N. , TOKATLIDIS I. S. 
Published: July 2013

SUMMARYCultivated lentil (Lens culinarisL.) landraces offer a challenge to exploiting their genetic variability and deriving new pure-line varieties. For insect-transmitted viruses, low densities favour increased virus spread. The objective of the present work was to evaluate a selection procedure applied within a landrace under ultra-low plant density and low-input conditions toward the isolation of high-performing genotypes that escape virus infection. Field trials were conducted through four growing seasons (2006–2011) in the Democritus University of Thrace research farm in Orestiada, Greece. Selection of individual plants for high grain yield was applied for three generations, while virus presence was tested by enzyme-linked immunosorbent assay in the seeds used or the plants selected in each selection cycle. Early high plant-to-plant phenotypic variability, reflected by high coefficient of variation (CV) values, was partly attributed to virus infection. However, sister lines were consistently higher yielding and of lower CV than the mother population (MP). Second generation lines yielded up to 136 and 23% more than the source landrace at the ultra-low density and dense stand, respectively.Pea seed-borne mosaic viruswas detected in the seeds of the MP, whereasbean yellow mosaic virusandbean leafroll viruswere mainly involved in the subsequent selection rounds. In general, the highest-yielding plants were free of the viruses detected during experimentation. It was concluded that selection at ultra-low density of the highest-yielding plants from the sister lines with the lowest CV constitute an effective way to improve the health status of the seeds produced and result in high yielding and potentially virus-tolerant pure-line varieties.
YouTube as a source of information on rhinosinusitis: the good, the bad and the ugly
Authors: Biggs T C , Bird J H , Harries P G , Salib R J 
Published: July 2013

AbstractObjective:YouTube is an internet-based repository of user-generated content. This study aimed to determine whether YouTube represented a valid and reliable patient information resource for the lay person on the topic of rhinosinusitis.Methods:The study included the first 100 YouTube videos found using the search term ‘sinusitis’. Videos were graded on their ability to inform the lay person on the subject of rhinosinusitis.Results:Forty-five per cent of the videos were deemed to provide some useful information. Fifty-five per cent of the videos contained little or no useful facts, 27 per cent of which contained potentially misleading or even dangerous information. Videos uploaded by medical professionals or those from health information websites contained more useful information than those uploaded by independent users.Conclusion:YouTube appears to be an unreliable resource for accurate and up to date medical information relating to rhinosinusitis. However, it may provide some useful information if mechanisms existed to direct lay people to verifiable and credible sources.
Rebuilding the Navel of the Earth: Buddhist pilgrimage and transnational religious networks
Authors: GEARY DAVID 
Published: July 2013

AbstractCentral to the modern rebirth of Bodh Gaya as the place of Buddha's enlightenment is the growing influence of Buddhist missionaries and transnational religious networks on this pilgrimage landscape in North India. Although this process began in the late nineteenth century, it was not until after India's independence that Buddhism became an integral part of the nation-building project and a key site of post-colonial diplomacy with neighbouring Asian countries. Symbolic of these international and diplomatic ties are the increasing numbers of foreign Buddhist monasteries and temples that have acquired land around Bodh Gaya. This paper seeks to document the historical and transnational religious processes that support the growing globalization of Bodh Gaya and to survey the institutional means through which monasteries have elevated the Buddhist memory of the site. In tracing these different national and regional networks of Buddhism, I argue that there is an underlying tension between Buddhist culture anchored in the national polity and the forces of globalization and religious experience that seek to transcend it.
Does the carotenoid-based colouration ofPolymorphus minutusfacilitate its trophic transmission to definitive hosts?
Authors: JACQUIN L. , MORI Q. , MÉDOC V. 
Published: July 2013

SUMMARYFreshwater gammarids infected with the acanthocephalan parasitePolymorphus minutusshow behavioural alterations but also differ from uninfected individuals in their appearance because of the carotenoid-based colouration of the parasite visible through the cuticle. However, it's not clear whether this phenotypic alteration is an adaptation favouring parasite transmission to the definitive host. To test this hypothesis, we investigated the selective preference of mallard towards two prey types: uninfected gammarids on which we applied a dot of inconspicuous brown paint, and uninfected gammarids on which we applied a dot of bright orange paint to mimic the change in appearance due toP. minutuswithout changes in host behaviour. Mallards showed a significant preference for orange-painted gammarids regardless of how gammarids were distributed (isolated or aggregated). This suggests that parasite's colouration may play a role in enhanced transmission to definitive avian hosts. The role ofP. minutus’ colouration in the conspicuousness of gammarids has however to be balanced by the extent to which mallards use visual cues to forage in the field. From the perspective of a multidimensional manipulation, this study suggests that the change in appearance may act synergistically with the changes in behaviour to promote transmission to waterbirds.
Detection of human taeniases in Tibetan endemic areas, China
Authors: LI TIAOYING , CHEN XINGWANG , YANAGIDA TETSUYA , WANG HAO , LONG CHANGPING , SAKO YASUHITO , OKAMOTO MUNEHIR , WU YUNFEI , GIRAUDOUX PATRICK , RAOUL FRANCIS , NKOUAWA AGATHE , NAKAO MINORU , CRAIG PHILIP S. , ITO AKIRA 
Published: July 2013

SUMMARYDetection of taeniasis carriers ofTaenia soliumis essential for control of cysticercosis in humans and pigs. In the current study, we assessed the positive detection rate of a self-detection tool, stool microscopy with direct smear and coproPCR for taeniasis carriers in endemic Tibetan areas of northwest Sichuan. The self-detection tool through questioning about a history of proglottid expulsion within the previous one year showed an overall positive detection rate of more than 80% forTaenia saginata, T. soliumandT. asiatica. The positive detection rate was similar forT. saginataandT. solium. In 132 taeniid tapeworm carriers, 68 (51·5%) were detected by microscopy and 92 (69·7%) were diagnosed by coproPCR. A combination of microscopy and coproPCR increased the positive detection rate to 77·3%. There remained 10 cases (7·6%) coproPCR negative but microscopy positive. Due to the high cost and complicated process, coproPCR is required for the identification ofTaeniaspecies only when necessary, though it had a significant higher positive detection rate than microscopy. Combined use of self-detection and stool microscopy are recommended in community-based mass screening for taeniases in this Tibetan area or in other situation-similar endemic regions.