bluuebunny/crossref_metadata_2025_split huggingface dataset:
Is it all hype? ChatGPT’s performance and disruptive potential in the accounting and auditing industries
Authors: Eulerich Marc , Sanatizadeh Aida , Vakilzadeh Hamid , Wood David A. 
Published: June 2024

AbstractChatGPT frequently appears in the media, with many predicting significant disruptions, especially in the fields of accounting and auditing. Yet research has demonstrated relatively poor performance of ChatGPT on student assessment questions. We extend this research to examine whether more recent ChatGPT models and capabilities can pass major accounting certification exams including the Certified Public Accountant (CPA), Certified Management Accountant (CMA), Certified Internal Auditor (CIA), and Enrolled Agent (EA) certification exams. We find that the ChatGPT 3.5 model cannot pass any exam (average score across all assessments of 53.1%). However, with additional enhancements, ChatGPT can pass all sections of each tested exam: moving to the ChatGPT 4 model improved scores by an average of 16.5%, providing 10-shot training improved scores an additional 6.6%, and allowing the model to use reasoning and acting (e.g., allow ChatGPT to use a calculator and other resources) improved scores an additional 8.9%. After all these improvements, ChatGPT passed all exams with an average score of 85.1%. This high performance indicates that ChatGPT has sufficient capabilities to disrupt the accounting and auditing industries, which we discuss in detail. This research provides practical insights for accounting professionals, investors, and stakeholders on how to adapt and mitigate the potential harms of this technology in accounting and auditing firms.
Stigma Towards People Living with Co-occurring Schizophrenia Spectrum and Substance Use Disorders: A Scoping Review
Authors: Hobern Beth , Carrotte Elise R. , Rehm Imogen C. , Blanchard Michelle , Groot Christopher 
Published: June 2024

AbstractThis scoping review mapped the extant research literature examining stigma towards people living with co-occurring schizophrenia spectrum and substance use disorders (SZSUD). Five online databases were searched for research published before September 2023. Eighteen relevant studies were identified, including six from the perspective of people living with SZSUD and 12 exploring public stigma towards the conditions. The majority of studies (n = 11) explored stigma from care providers, including healthcare, mental healthcare, and addiction clinicians and carers. In general, responses to people living with SZSUD were more negative than towards people living with either condition alone. People living with SZSUD identified numerous challenges associated with experienced, anticipated, internalised, and perceived stigma. Additional research is required to determine the extent and scope of the stigma faced by people living with SZSUD and how stigma manifests in other types of interpersonal relationships. Implications and additional recommendations for future research are discussed.
Continuous mobile measurement of camptocormia angle using four accelerometers
Authors: Naderi Beni K. , Knutzen K. , Kuhtz-Buschbeck J. P. , Margraf N. G. , Rieger R. 
Published: June 2024

AbstractCamptocormia, a severe flexion deformity of the spine, presents challenges in monitoring its progression outside laboratory settings. This study introduces a customized method utilizing four inertial measurement unit (IMU) sensors for continuous recording of the camptocormia angle (CA), incorporating both the consensual malleolus and perpendicular assessment methods. The setup is wearable and mobile and allows measurements outside the laboratory environment. The practicality for measuring CA across various activities is evaluated for both the malleolus and perpendicular method in a mimicked Parkinson disease posture. Multiple activities are performed by a healthy volunteer. Measurements are compared against a camera-based reference system. Results show an overall root mean squared error (RMSE) of 4.13° for the malleolus method and 2.71° for the perpendicular method. Furthermore, patient-specific calibration during the standing still with forward lean activity significantly reduced the RMSE to 2.45° and 1.68° respectively. This study presents a novel approach to continuous CA monitoring outside the laboratory setting. The proposed system is suitable as a tool for monitoring the progression of camptocormia and for the first time implements the malleolus method with IMU. It holds promise for effectively monitoring camptocormia at home.
Research Translation to Promote Urban Health in Latin America: The SALURBAL Experience
Authors: Slesinski S. Claire , Indvik Katherine , Barrientos-Gutierrez Tonatiuh , Bolinaga Andrea , Caiaffa Waleska Teixeira , Diez-Canseco Francisco , Miranda J. Jaime , Rodriguez Daniel A. , Sarmiento Olga L. , Siri José G. , Vergara Alejandra Vives , Roux Ana V. Diez ,   The SALURBAL group
Published: June 2024

AbstractIn highly urbanized and unequal Latin America, urban health and health equity research are essential to effective policymaking. To ensure the application of relevant and context-specific evidence to efforts to reduce urban health inequities, urban health research in Latin America must incorporate strategic research translation efforts. Beginning in 2017, the Urban Health in Latin America (SALURBAL) project implemented policy-relevant research and engaged policymakers and the public to support the translation of research findings. Over 6 years, more than 200 researchers across eight countries contributed to SALURBAL’s interdisciplinary network. This network allowed SALURBAL to adapt research and engagement activities to local contexts and priorities, thereby maximizing the policy relevance of research findings and their application to promote policy action, inform urban interventions, and drive societal change. SALURBAL achieved significant visibility and credibility among academic and nonacademic urban health stakeholders, resulting in the development of evidence and tools to support urban policymakers, planners, and policy development processes across the region. These efforts and their outcomes reveal important lessons regarding maintaining flexibility and accounting for local context in research, ensuring that resources are dedicated to policy engagement and dissemination activities, and recognizing that assessing policy impact requires a nuanced understanding of complex policymaking processes. These reflections are relevant for promoting urban health and health equity research translation across the global south and worldwide. This paper presents SALURBAL’s strategy for dissemination and policy translation, highlights innovative initiatives and their outcomes, discusses lessons learned, and shares recommendations for future efforts to promote effective translation of research findings.
A New Method for Low Density Distribution Modeling and Near Threatened Species: The Study Case of Plectrohyla Guatemalensis
Authors: Ballesteros Miguel , Díaz-Avalos Carlos , Hernández Omar , Garro Guillermo 
Published: June 2024

AbstractWe introduce a model that can be used for the description of the distribution of species when there is scarcity of data, based on our previous work (Ballesteros et al. J Math Biol 85(4):31, 2022). We address challenges in modeling species that are seldom observed in nature, for example species included in The International Union for Conservation of Nature’s Red List of Threatened Species (IUCN 2023). We introduce a general method and test it using a case study of a near threatened species of amphibians called Plectrohyla Guatemalensis (see IUCN 2023) in a region of the UNESCO natural reserve “Tacaná Volcano”, in the border between Mexico and Guatemala. Since threatened species are difficult to find in nature, collected data can be extremely reduced. This produces a mathematical problem in the sense that the usual modeling in terms of Markov random fields representing individuals associated to locations in a grid generates artificial clusters around the observations, which are unreasonable. We propose a different approach in which our random variables describe yearly averages of expectation values of the number of individuals instead of individuals (and they take values on a compact interval). Our approach takes advantage of intuitive insights from environmental properties: in nature individuals are attracted or repulsed by specific features (Ballesteros et al. J Math Biol 85(4):31, 2022). Drawing inspiration from quantum mechanics, we incorporate quantum Hamiltonians into classical statistical mechanics (i.e. Gibbs measures or Markov random fields). The equilibrium between spreading and attractive/repulsive forces governs the behavior of the species, expressed through a global control problem involving an energy operator.
Optimization of window settings for coronary arteries assessment using spectral CT-derived virtual monoenergetic imaging
Authors: D’Angelo Tommaso , Mastrodicasa Domenico , Lanzafame Ludovica R. M. , Yel Ibrahim , Koch Vitali , Gruenewald Leon D. , Sharma Simran P. , Ascenti Velio , Micari Antonino , Blandino Alfredo , Vogl Thomas J. , Mazziotti Silvio , Budde Ricardo P. J. , Booz Christian 
Published: June 2024

Abstract
Purpose
To determine the optimal window setting for virtual monoenergetic images (VMI) reconstructed from dual-layer spectral coronary computed tomography angiography (DE-CCTA) datasets.

Material and methods
50 patients (30 males; mean age 61.1 ± 12.4 years who underwent DE-CCTA from May 2021 to June 2022 for suspected coronary artery disease, were retrospectively included. Image quality assessment was performed on conventional images and VMI reconstructions at 70 and 40 keV. Objective image quality was assessed using contrast-to-noise ratio (CNR). Two independent observers manually identified the best window settings (B-W/L) for VMI 70 and VMI 40 visualization. B-W/L were then normalized with aortic attenuation using linear regression analysis to obtain the optimized W/L (O-W/L) settings. Additionally, subjective image quality was evaluated using a 5-point Likert scale, and vessel diameters were measured to examine any potential impact of different W/L settings.

Results
VMI 40 demonstrated higher CNR values compared to conventional and VMI 70. B-W/L settings identified were 1180/280 HU for VMI 70 and 3290/900 HU for VMI 40. Subsequent linear regression analysis yielded O-W/L settings of 1155/270 HU for VMI 70 and 3230/880 HU for VMI 40. VMI 40 O-W/L received the highest scores for each parameter compared to conventional (all p < 0.0027). Using O-W/L settings for VMI 70 and VMI 40 did not result in significant differences in vessel measurements compared to conventional images.

Conclusion
Optimization of VMI requires adjustments in W/L settings. Our results recommend W/L settings of 1155/270 HU for VMI 70 and 3230/880 HU for VMI 40.
The Link Between Matrix Metalloproteinases and Alzheimer’s Disease Pathophysiology
Authors: Radosinska Dominika , Radosinska Jana 
Published: June 2024

AbstractAlzheimer’s disease (AD) is a major contributor to dementia and the most common neurodegenerative disorder. In AD pathophysiology, matrix metalloproteinases (MMPs)—proteolytic enzymes, best known to be responsible for remodeling and degradation of the extracellular matrix—were suggested to play an important role. Due to the diverse nature of the published data and frequent inconsistent results presented in available papers, it was considered essential to analyze all aspects of MMP literature with respect to AD pathophysiology and attempt to outline a unifying concept for understanding their role in AD. Thus, the main contribution of this review article is to summarize the most recent research on the participation of MMP in AD pathophysiology obtained using the cell cultures to understand the molecular principles of their action. Furthermore, an updated comprehensive view regarding this topic based exclusively on papers from human studies is provided as well. It can be concluded that determining the exact role of any particular MMPs in the AD pathophysiology holds promise for establishing their role as potential biomarkers reflecting the severity or progression of this disease or for developing new therapeutic agents targeting the processes that lead to AD.
Neck Dissection in cT3/T4 Mucoepidermoid Carcinoma of the Oral Cavity and Oropharynx
Authors: Patel Rushi , Patel Aman M. , Revercomb Lucy , Patel Amy , Tseng Christopher C. , Park Richard Chan Woo 
Published: June 2024

AbstractPrevious research has reported high occult nodal metastases rates for T3/T4 mucoepidermoid carcinoma (MEC) of the oropharynx (OP) and oral cavity (OC). Our study evaluates if there is a benefit of neck dissection (ND) in these patients. The 2004–2016 National Cancer Database was queried for cases of adult MEC of the OC and OP. Patients with clinical T3/T4 disease were included while those with metastatic disease were excluded. Patients were divided into two cohorts: those treated with and without ND. Univariate chi-square, Kaplan-Meier, and multivariable Cox regression analyses were implemented. A total of 243 patients met inclusion criteria, of which 79 (32.5%) underwent ND. The majority of patients were less than 60 years old (60.1%), White (76.2%), and male (53.5%). 92 (37.9%) patients had clinically node-positive (cN+) disease. ND patients had higher rates of cN + disease (53.2% vs. 30.5%, p = 0.002). Of patients undergoing ND, 35 (44.3%) had cN0 disease while 42 (53.2%) had cN + disease. ND patients more commonly had grade III/IV tumors (45.1% vs. 23.4%, p = 0.002). Upon examination of dissected nodes, 20.3% of cN0 patients undergoing ND were found to have occult nodal metastases. There was no significant difference in 5-year overall survival between patients with and without ND (61.8% vs. 53.6%, p = 0.610), even on multivariable Cox analysis (hazard ratio: 1.52, 95% confidence interval: 0.73–3.18, p = 0.269). Our study found patients with cN0 MEC of the OC and OP have a high rate (20.3%) of occult nodal metastasis. In this cohort, patients with ND were not found to have improved survival, possibly due to statistical underpowering. Further research is needed to evaluate the indications and benefit of ND for this rare tumor presentation.
‘Familiness’ diversification and recognition: intergenerational changes in mobile ‘ndrangheta families in Australia
Authors: Sergi Anna 
Published: June 2024

AbstractMafia-type families, envisioned as intergenerational (criminal) dynasties or family-based criminal groups, are shaped by recognition in the ‘underworld’ and affected by changes in their familiness. In Australia, mafia-type families or dynasties connected to the Calabrian ‘ndrangheta have been successful at exploiting licit and illicit opportunities across generations and places also thanks to their recognition as well as reputation. In this article we explore how mafia-type families or dynasties experience familiness diversification, including intergenerational changes, transculturation, and external factors, and how this relates to their recognition in the underworld, by other criminal groups or by law enforcement. Based on document analysis and interviews, and building on a new analytical framework, we present four ideal-types mafia-type families in Australia: gatekeepers, holdovers, newcomers, and vanishers. This is the first study that considers how mafia organisations evolve in their most fundamental forms abroad, and some implications of such evolution go against mainstream understandings of mafia mobility studies.
Uridine-Loaded Polycaprolactone Nanofiber Mats as a Novel Wound Dressing
Authors: Mergen Hilmiye Sule , Duzyer Gebizli Sebnem , Ermis Erkan , Cansev Mehmet , Isik Dokuzoglu Sema , Goktalay Gokhan 
Published: June 2024

AbstractIn the current study, a novel wound dressing material for an effective wound healing was developed by loading Uridine (URD), an endogenous compound known for its regenerative properties, into polycaprolactone (PCL) nanofibers. Initially, PCL nanofibers without URD were fabricated from different PCL solutions (7, 8, 10 and 11% w/w) by electrospinning and optimum PCL concentration (10% w/w) for URD loading was determined. After loading URD at different concentrations (0.1, 0.5 and 1% w/w) into 10% PCL solution, PCL/URD nanofibers were electrospun. Structural characteristics, release kinetics as well as in vitro and in vivo effects of the PCL/URD nanofibers were studied and in vivo effects were compared with a conventional wound dressing material. Loading URD increased nanofiber diameters from 248 to 509 nm and decreased contact angles from 123.76° to 94.3° with increasing URD concentrations. URD showed a burst release in the first 60 min following a more gradual release up to the 5th day which best fitted with Korsmeyer–Peppas model. PCL/URD mats provided enhanced viability in vitro in MTT assay using mouse L929 fibroblast cell line. Furthermore, in vivo wound closure studies revealed an immediate and robust wound healing in rats treated with PCL/URD mats compared to PCL mats without URD as well as the conventional wound dressing material. These data suggest that URD-loaded PCL nanofiber mats are promising materials as wound dressing.
Graphical abstract
Cognitive and Emotional Effect of a Multi-species Probiotic Containing Lactobacillus rhamnosus and Bifidobacterium lactis in Healthy Older Adults: A Double‐Blind Randomized Placebo‐Controlled Crossover Trial
Authors: Ruiz-Gonzalez Cristofer , Cardona Diana , Rueda-Ruzafa Lola , Rodriguez-Arrastia Miguel , Ropero-Padilla Carmen , Roman Pablo 
Published: June 2024

AbstractAs the population ages, cognitive decline becomes more common. Strategies targeting the gut-brain axis using probiotics are emerging to achieve improvements in neuropsychiatric and neurological disorders. However, the beneficial role of probiotics on brain function in healthy older adults remains unclear. Our aim was to evaluate a multi-species probiotic formulation as a therapeutic approach to reduce emotional and cognitive decline associated with aging in healthy adults. A randomized double-blind placebo-controlled crossover trial was conducted. The study involved a 10-week intervention where participants consumed the assigned probiotic product daily, followed by a 4-week washout period before the second condition started. Cognitive function was assessed using the Mini-Mental State Examination (MMSE) and the Psychological Experiments Construction Language Test Battery. At the emotional level, the Beck Depression Inventory (BDI) and the State-Trait Anxiety Inventory (STAI) were used. Thirty-three participants, recruited between July 2020 and April 2022, ingested a multispecies probiotic (Lactobacillus rhamnosus and Bifidobacterium lactis). After the intervention, noticeable enhancements were observed in cognitive function (mean difference 1.90, 95% CI 1.09 to 2.70, p < 0.005), memory (mean difference 4.60, 95% CI 2.91 to 6.29, p < 0.005) by MMSE and digit task, and depressive symptoms (mean difference 4.09, 95% CI 1.70 to 6.48, p < 0.005) by BDI. Furthermore, there were significant improvements observed in planning and problem-solving skills, selective attention, cognitive flexibility, impulsivity, and inhibitory ability. Probiotics administration improved cognitive and emotional function in older adults. Limited research supports this, requiring more scientific evidence for probiotics as an effective therapy for cognitive decline. This study has been prospectively registered at ClinicalTrials.gov (NCT04828421; 2020/July/17).
After-effects of a closed copper mine: detailed analysis of environmental impacts in soil and plant samples
Authors: Konanç Mustafa Umut , Değermenci Gökçe Didar , Kariper İshak Afşin , Yavuz Emine 
Published: June 2024

AbstractIn several countries around the world, abandoned mining sites are blighted by pollution from metal and metalloids. Generated by mining processes, toxic pollutants have lasting effects on the ecosystem. The study examined the environmental impact of waste from a copper mine that was operated by the Caucasus Copper Limited Company between 1905 and 1928, revised and commissioned by Etibank in 1936, and ceased operations 75 years ago. Soil and plant samples (needles of Scotch pine, Pinus sylvestris L.) were collected from five specific regions around the mine and the levels of potentially toxic elements (PTEs) were determined, including As, Zn, Pb, Cd, Ni, Mn, Cr, Cu, Al, and Fe. The data obtained were used to calculate the enrichment factor (EF), geo-accumulation index (Igeo), contamination factor (CF), ecological risk index (ERI), human health risk index (BCF), and plant enrichment factor (EFPlant). In soil samples, the average EF values of certain elements such as As (453), Cu (59.9), Pb (30.7), Zn (5.26) were detected at high levels. However, average Igeo values indicate high pollution levels for As (8.25), Cd (6.72), Cu (4.94), Pb (4.33) and Zn (2.42), indicating the existence of serious ecological risks in the affected areas. Additionally, the average CF values indicate serious pollution levels from heavy metals such as As (1605), Cd (584), Pb (99.4), Cu (81.9), and Zn (14.6), highlighting the extensive pollution situation resulting from mining activities. Meanwhile, average ERI values indicate that Cd, As, Cu, and Pb pose serious ecological risks in the study areas.These PTEs were found in high concentrations in the waste tail and dump. Furthermore, the analysis determined that there was enrichment for Mn, Cd, Al, Cu, Pb, and Fe elements in plant samples. These PTEs have the potential to spread more widely depending on seasonal conditions and local topography. This situation demonstrates the need to measure metal and metalloids concentrations at certain times, taking into account the potential for environmental pollution of surface runoff water and underground resources in areas with high drainage potential from acid mines, such as at the Kuvarshan mine tailings site.
Digging into boring bryozoans: new characters and new species of Immergentiidae
Authors: Johnson Mildred J. , Saadi Ahmed J. , Kuklinski Piotr , Smith Abigail M. , López-Gappa Juan , Schwaha Thomas 
Published: June 2024

AbstractImmergentia is an endolithic genus of ctenostome bryozoans and the sole member of the Immergentiidae. Etchings of their typical spindled-shaped and sometimes enantiomorphic borehole aperture in calcium carbonate substrates are accomplished by chemical dissolution. The tentacle crown of the bryozoan is essentially the only body part that extends beyond the shell surface when protruded. Previously, species were mainly described using external colony and zooidal characteristics or whole mounts, with partial histological sections conducted on a single species in 1947. Modern approaches, however, are hitherto missing. We examined the soft body morphology of Immergentia from different locations with confocal laser scanning microscopy and the production of 3D reconstructions. In addition, zooidal characteristics such as tentacle number, size, tubulets, and interzooidal distances were used to distinguish and describe species. The combination of conventional and modern methods revealed the presence of a cardiac constrictor and intercalary kenozooids that can interpose between the cystid appendages, something not previously reported in immergentiids, thus necessitating an amendment of the family diagnosis. The polypide typically has eight to ten tentacles, and the anus is positioned in the low or mid-lophophoral area. In addition, sequence data, including the mitogenome and the nuclear ribosomal genes (18S and 28S) of four species from five locations, are presented for the first time. Based on molecular and morphological data, a novel intertidal immergentiid from France, Immergentia stephanieae sp. nov., and a subtidal species from New Zealand, I. pohowskii sp. nov., are described. This work supplements the rather sparse existing knowledge on Immergentiidae and proposes additional characteristics to complement existing descriptions in order to enhance future species identification.