bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multi-modal co-learning with attention mechanism for head and neck tumor segmentation on 18FDG PET-CT
Authors: Cho Min Jeong , Hwang Donghwi , Yie Si Young , Lee Jae Sung 
Published: July 2024

Abstract
Purpose
Effective radiation therapy requires accurate segmentation of head and neck cancer, one of the most common types of cancer. With the advancement of deep learning, people have come up with various methods that use positron emission tomography-computed tomography to get complementary information. However, these approaches are computationally expensive because of the separation of feature extraction and fusion functions and do not make use of the high sensitivity of PET. We propose a new deep learning-based approach to alleviate these challenges.

Methods
We proposed a tumor region attention module that fully exploits the high sensitivity of PET and designed a network that learns the correlation between the PET and CT features using squeeze-and-excitation normalization (SE Norm) without separating the feature extraction and fusion functions. In addition, we introduce multi-scale context fusion, which exploits contextual information from different scales.

Results
The HECKTOR challenge 2021 dataset was used for training and testing. The proposed model outperformed the state-of-the-art models for medical image segmentation; in particular, the dice similarity coefficient increased by 8.78% compared to U-net.

Conclusion
The proposed network segmented the complex shape of the tumor better than the state-of-the-art medical image segmentation methods, accurately distinguishing between tumor and non-tumor regions.
Ranking occupations by their proximity to workers’ profiles
Authors: Bächli Mirjam , Benghalem Hélène , Tinello Doriana , Aschwanden Damaris , Zuber Sascha , Kliegel Matthias , Pellizzari Michele , Lalive Rafael 
Published: July 2024

AbstractInformation friction makes it difficult for job seekers to find new employment opportunities. We propose a method for providing individual-specific occupation recommendations by ranking occupations based on their proximity to the worker’s profile. We identify a set of twelve skills, abilities and work styles that capture the worker-oriented requirements of all occupations and discuss how to measure these items using online questions and tasks. We use the Euclidean distance between the measured items pertaining to a worker and the requirements of an occupation to measure the proximity between job seekers and occupations. We show that the proximity between job seekers’ profiles and their preunemployment occupation predicts their intention to change occupations, thus suggesting that our method captures a meaningful conceptualization of mismatch. We also show that our method generates recommendations that differ from the previous occupations of mismatched job seekers, thereby potentially expanding their search scope.
The impact of corporate governance on firm performance: panel data evidence from S&P 500 Information Technology
Authors: Danilov Georgiana 
Published: July 2024

AbstractThis research is important for both the academic and business environments due to the extraordinary results obtained. Additionally, the significance of the study is also attributed to the addressed topic, which is intensively studied in the world of corporate finance. The primary aim of this research is to scrutinize a cohort of 66 information and technology (IT) companies, all of which are constituents of the American Standard and Poor’s 500 Index (S&P 500). The study period spans two decades, covering the years 2003–2022. To summarize the outcomes, the analytical framework incorporated linear models with both fixed (fe) and random effects (re), as well as quantile regression models. This study's key outcomes highlight that firm size, sales growth, current ratio, long-term debt to capital, free cash flow, asset turnover and receivable turnover, board meeting frequency, female board representation, chief executive officer age, audit committee independence, and the presence of compensation and nomination committees, alongside a pandemic indicator, positively impact firm performance. Conversely, firm age, dividend payout ratio, effective tax rate, board size, chief executive officer duality, and corporate social responsibility committee presence have negative effects on performance. Also, regarding quantile regressions, CEO duality significantly influences companies with high profitability rates, and companies with low to medium profitability rates are more strongly and negatively influenced by board size. The implications of the core policy in this research focusing on corporate governance will consider certain rules and guidelines regarding financial transparency and protecting shareholders' interests. Additionally, it will take into account the independence of the board of directors and the presence of its committees, as well as ethical leadership practices.
Effects of rosuvastatin on serum asymmetric dimethylarginine levels and incidence of long-term cardiovascular events in patients with hyperlipidaemia and H-type hypertension
Authors: Jiang Jinzhong , Miao Wei , Guo Hua , Tian Wenyan 
Published: July 2024

Aims/Background Rosuvastatin is a common lipid-lowering statin on the market, but its impact on the incidence of long-term cardiovascular events is not well clarified. This study aimed to explore the effects of rosuvastatin on serum asymmetric dimethylarginine (ADMA) levels and the incidence of long-term cardiovascular events in patients with hyperlipidaemia and H-type hypertension. Methods This retrospective study included 158 patients with hyperlipidaemia and H-type hypertension who were treated in the Hebei Cangzhou Hospital of Integrated Traditional Chinese Medicine and Western Medicine from August 2015 to August 2016. The patients were divided into an occurrence group and a non-occurrence group according to the occurrence of long-term cardiovascular events following the resuvostatin treatment. The changes in blood lipids, blood pressure, serum ADMA levels and vascular endothelial function indexes before and after treatment were compared, and the effect of ADMA on the occurrence of long-term cardiovascular events and its predictive efficacy were analysed using the Spearman correlation test and receiver operating characteristics (ROC) curve. Results After treatment, the levels of serum total cholesterol, low-density lipoprotein cholesterol, triglyceride, serum ADMA and blood pressure became significantly lower (p < 0.001), with high-density lipoprotein cholesterol exhibiting no significant difference. Twenty-two cases developed long-term cardiovascular events after the treatment, with an incidence of 13.92%. The occurrence group had significantly higher serum ADMA levels than the non-occurrence group (p < 0.001). The rosuvastatin treatment also lowered the levels of endothelin-1 and high-sensitivity C-reactive protein and increased the nitric oxide level (p < 0.001). Spearman correlation analysis showed that serum ADMA levels were positively correlated with the occurrence of long-term cardiovascular events (r=0.462, p < 0.001). Meanwhile, according to the ROC curve, serum ADMA had a good predictive efficacy for long-term cardiovascular events, with an area under the curve of 0.885 (95% confidence interval 0.808–0.963; p < 0.001). Conclusion Rosuvastatin can reduce ADMA levels and exert vascular protective effects. The increase in serum ADMA levels is closely related to the occurrence of long-term cardiovascular events in patients with hyperlipidaemia and H-type hypertension, serving as a potential clinical predictor to guide disease prevention and treatment.
PREVISÕES DE SÉRIES DE TEMPERATURA NA MICRORREGIÃO DE PIRASSUNUNGA (SP)
Authors: Teixeira Bruno Eduardo , Antonio de Souza Luiz Gustavo , Tech Adriano Rogério Bruno 
Published: July 2024

Observa-se um aumento cada vez maior das consequências do fenômeno chamado de mudanças climáticas, que se tem manifestado através de fatos que podem ser considerados fora da normalidade, como pode ser observado através de chuvas e ventos fortes, além de enchentes e quedas de árvores que causam grandes prejuízos as mais variadas cidades e regiões em diversos pontos do país e do mundo. A pesquisa atual tem por objetivo geral analisar o comportamento da temperatura na microrregião de Pirassununga no interior do estado de São Paulo com o intuito de responder se as mudanças são significativas ao ponto de considerar que há mudança provocada pelas alterações climáticas globais, para a realização desse estudo foi utilizado como base uma série temporal de 1988 a 2018, onde foi observado o comportamento da temperatura mínima, média e máxima. Em um primeiro momento foi possível observar um comportamento sazonal para as situações em análise da série temporal, mas para aprimorar a compreensão e aprofundar melhor o estudo da série optou-se por dividir o modo de estudo em três subgrupos distintos, a partir disso utilizou modelos estatísticos para a continuidade da pesquisa. Como método principal de estudo nesta pesquisa foi utilizado a estimação de modelos de séries temporais da classe ARIMA. Conclui-se a partir dos resultados que há mudanças nas séries temporais significativas no componente médias-móveis, isto é, infere-se como movimento oriundo das mudanças climáticas.
Spontaneous Right Intrapetrous Internal Carotid Dissection in a Patient With Active COVID-19
Authors: Noble Oscar , Sprung Keri , Diaz Orlando , Coulter Stephanie , Hernandez-Vila Eduardo 
Published: July 2024

Abstract
Spontaneous cervical artery dissection, a nontraumatic tear in the wall of an internal carotid or vertebral artery, is a common cause of stroke, particularly in patients younger than 40 years of age; however, petrous internal carotid artery dissection is extremely rare. This case report describes a 50-year-old woman who had a spontaneous intrapetrous internal carotid dissection thought to be secondary to active SARS-CoV-2 infection; the dissection was treated successfully with a flow-diverter stent.
Bilirubin measurements in neonates: uniform neonatal treatment can only be achieved by improved standardization
Authors: Hulzebos Christian V. , Camara Johanna E. , van Berkel Miranda , Delatour Vincent , Lo Stanley F. , Mailloux Agnès , Schmidt Marcel C. , Thomas Mercy , Mackay Lindsey G. , Greaves Ronda F. 
Published: July 2024

Abstract
Measurement of total bilirubin (TBil) concentration in serum is the gold standard approach for diagnosing neonatal unconjugated hyperbilirubinemia. It is of utmost importance that the measured TBil concentration is sufficiently accurate to prevent under treatment, unnecessary escalation of care, or overtreatment. However, it is widely recognized that TBil measurements urgently require improvement in neonatal clinical chemistry. External quality assessment (EQA) programs for TBil assess for differences between laboratories and provide supporting evidence of significant differences between various methods, manufacturers and measurement platforms. At the same time, many countries have adopted or only slightly adapted the neonatal hyperbilirubinemia management guidelines from the USA or UK, often without addressing differences in the methodology of TBil measurements. In this report, we provide an overview of the components of bilirubin that are measured by laboratory platforms, the availability of current reference measurement procedures and reference materials, and the role of EQA surveys in this context. Furthermore, the current status of agreement in neonatal bilirubin against clinical decision thresholds is reviewed. We advocate for enhancements in accuracy and comparability of neonatal TBil measurements, propose a path forward to accomplish this, and reflect on the position of the International Federation for Clinical Chemistry and Laboratory Medicine (IFCC) Working Group Neonatal Bilirubin (WG-NB) in this matter.
Analysis of bioactive compounds present in Boerhavia elegans seeds by GC-MS
Authors: ALRaddadi Tahreer M. , Bahaffi Saleh O. , Alkhateeb Lateefa A. , Sadaka Mohammad W. 
Published: July 2024

Abstract

Boerhavia elegans L. (Nyctaginaceae) is a tropical plant widely distributed in the eastern part of Yemen, Oman, and many other countries. B. elegans is used in traditional medicine to treat inflammation, anemia, and urinary tract disorders. The seeds, called Alhydawan, are used as food additives to prepare porridge, one of the most popular foods in Yemen. The present study aims to analyze the bioactive constituents of the methanolic extract of B. elegans seeds after fractionation on silica gel column chromatography. The methanolic extract was subjected to column chromatography and eluted with a hexane and hexane diethyl ether mixture of different compositions. The eluted fractions were tested with thin-layer chromatography. The gas chromatography-mass spectrometry analysis of fractions indicated some compounds such as dodecane, 2,6,11-trimethyl, butylated hydroxytoluene, 2,6,10-trimethyltridecane, hexadecane,2,6,11,15-tetramethyl, nonadecane, 2-methyl, 7,9-di-tert-butyl-1-oxaspiro(4,5) deca-6,9-diene-2,8-dione, n-hexadecenoic acid, octadecanoic acid, bis(2-ethylhexyl) phthalate, 13-docosenamide, (Z)-, and phenol,2,4-bis(1,1-dimethyl ethyl) phosphite (3:1). Hence, B. elegans may have antimicrobial, anticancer, antioxidant, and antidiabetic activities due to the presence of secondary metabolites in the extract.
Homology modeling and molecular docking study of corticotrophin-releasing hormone: An approach to treat stress-related diseases
Authors: Ahmad Nasir , Khan Khalid , Khan Sher Wali , Ur Rashid Haroon , Irum  , Zahoor Muhammad , Umar Muhammad Naveed , Ullah Riaz , Ali Essam A. 
Published: July 2024

Abstract
Corticotropin-releasing hormone receptors (CRHRs), also termed corticotropin-releasing factor receptors, are linked to G-protein-coupled receptor class. Corticotropin-releasing hormone (CRH) is medically significant in stress, immune response, gastrointestinal motility, and eating patterns. It serves as a releasing hormone and is encoded by the CRH gene. It has been established that there are two subtypes of CRHRs: CRH1-R and CRH2-R. These receptors, representing types 1 and 2, respectively, play a crucial role in regulating biological functions triggered by CRH. To treat stress-related gut abnormalities and stress-related disorders, regulation and optimization of CRH1-R and CRH2-R have turned into a novel idea. The three-dimensional (3D) structure of CRH is not completely recognized, and it is believed that the peptide key unit is helical and both the ultimate edges are relatively unsaturated. We can envisage its 3D structure from the amino acid order of a model protein by homology modeling procedures using Molecular Operating Environment and the Iterative Threading Assembly Refinement program. The assessment and authentication of the 3D structure were performed with RAMPAGE and ERRATE online servers. Utilizing the 3D structure of the target protein and predictions of its active site assists us in the development of new drug candidates aimed at treating disorders associated with stress. CRHR was docked with 19 CP376395 analogs acting as antagonists.
(De)Constructing the Disruption: Enacted Sensemaking and Sensegiving in Institutionally Plural Fields
Authors: Kumar Amal , Higgins Monica C. 
Published: July 2024

Abstract
If an event happens in the woods, and nobody responds to it, is it a disruption? In this paper, we address a gap in the organizational sociology literature about how events are constructed as “institutional disruptions” in institutionally plural fields. We integrate the disconnected literatures of sensemaking/sensegiving and institutional pluralism to argue that institutional disruptions in institutionally plural fields are not coterminous with exogenous events, but rather are the result of a process of fieldwide sensemaking and sensegiving mediated by intermediary organizations. We use the American higher education community’s response to the Trump administration’s 2017 ‘travel ban’ as a paradigmatic example that illuminates these dynamics with some clarity. In particular, we illuminate the relationships between conditions of institutional pluralism, extra-field events, the social construction of meaning within fields, the role of intermediary organizations, and the nature of organizational actions in response. Emerging from our theoretical exploration, we offer implications and avenues for future research for organizational sociologists. Collectively, our theorizing opens the door for scholars to re-examine previously taken-for-granted assumptions about disruptions and better theorize the earliest moments of institutional change.
Gender equality policy of the Olympic Movement in Chinese sport governing bodies: the case of elite volleyball
Authors: Huang Xingmeng Ava , Lau Patrick Wing Chung 
Published: July 2024

Abstract

Objectives
This research based on the theoretical framework of globalisation focuses on the development of gender equality policy in the Olympic Movement and the implementation of IOC’s gender equality policy in the context of Chinese elite volleyball.

Methods
In addition to documentary analysis, 17 semi-structured interviews were conducted with key insiders within Chinese elite volleyball system to provide a comprehensive understanding of the IOC’s gender equality policy implementation. The analysis involved perspectives of athletes’ participation, coaching positions, and leadership roles according to three main elements of the IOC’s gender equality policy.

Results
The findings demonstrated that the responses of Chinese elite volleyball to IOC’s gender equality policy are participative, conflictual, and passive in terms of the gender balance of athletes’ participation, coaches’ positions, and the representation of leadership roles respectively.

Conclusions
IOC recommended subordinated stakeholders including NOCs to implement gender equality policy. The attitude of Chinese elite volleyball governing body towards gender equality is generally positive. However, IOC’s gender equality policy is not consistently transferred at national level. Policy might be implemented with symbolic measure in China without monitoring system. Referees should be included in policy contents in addition to athletes, coaches and leaders. In addition, since IOC’s gender equality policy and statistics have been keeping updated, further results with respect to the case of volleyball should be demonstrated in future research.
Social, Emotional, and Behavioral (SEB) Skills in the Workplace
Authors: Chen Lilang , Zhang Bo , Li Jian 
Published: July 2024

The current study sought to extend Soto et al. (2022)‘s results on social, emotional, and behavioral (SEB) skills to a work setting and answer three key questions. First, do SEB skills predict consequential work-related outcomes? Second, do SEB skills provide incremental validity over the Big Five personality traits in predicting the outcomes? Third, is the joint effect of SEB skills and traits additive or multiplicative? Results from a sample of real estate agents (N = 2,992) in China extend the criterion space of SEB skills by showing self-concepts of these skills are related to self-reported work outcomes such as citizenship behaviors and job satisfaction in a conceptually meaningful way. Further analyses show that these skill-outcome relationships remain robust after accounting for effects of traits, indicating SEB skills’ incremental validity beyond traits in predicting outcomes. Finally, comparisons between additive and multiplicative models show support for the former because the interaction effects of SEB skills and traits provide little meaningful information beyond the additive models. Based on these findings, we discuss the implications for the SEB skills literature and practice.
Emprendimiento social y desarrollo local. El caso de una comunidad alfarera en Oaxaca, México
Authors: Cruz Domínguez Enrique , Valadez Solana Brenda , Cruz Cabrera Blasa 
Published: July 2024

El emprendimiento social (ES) se caracteriza por ser una actividad innovadora que busca soluciones a problemas sociales y que se dirige a generar valor social y económico en los habitantes de una comunidad. El desarrollo local (DL) es un proceso que busca mejorar las condiciones económicas, sociales y ambientales de un determinado territorio a partir del aprovechamiento de los recursos endógenos. Existe un vínculo entre el ES, el DL y la empresa social siendo las asociaciones una de las formas más conocidas de empresa social. Por ello, el objetivo de este estudio es analizar la relación del ES en asociaciones de artesanos alfareros con el DL de la comunidad Santa María Atzompa, Oaxaca, México. En cuestión metodológica, se realizó una investigación de tipo cuantitativo con un alcance descriptivo-explicativo y corte transversal. La técnica utilizada fue la encuesta cara a cara, en la que se aplicó un cuestionario estructurado con escala de Likert de cinco puntos a 68 artesanos alfareros integrantes de asociaciones del municipio de estudio. Los resultados arrojaron que, de los 68 artesanos alfareros encuestados, 79.41% fueron mujeres y 20.59% fueron hombres. Se identificó que las edades oscilan entre los 23 y los 84 años, la mayoría (73%) tiene entre 50 y 75 años. Además, todos los encuestados comentaron que el rango de edad estimada en la que se iniciaron en la elaboración de artesanías de barro es de 8-10 años. Los resultados demuestran que el ES tiene una relación directa y positiva en el DL (r=.673, p≤0.001) de Santa María Atzompa. El ES se explica mediante sus dimensiones capital social, capital humano y autogestión, mientras que el DL es explicado principalmente en sus dimensiones cultural, social y económica. La dimensión económica del DL es la que guarda mayor relación con el ES. Las asociaciones como formas de ES en Santa María Atzompa son auto generadoras de empleo e ingresos, preservan la cultura, fomentan la cohesión y participación social.
Mortality Surveillance for the COVID-19 Pandemic: Review of the Centers for Disease Control and Prevention’s Multiple System Strategy
Authors: Khan Diba , Park Meeyoung , Grillo Peter , Rossen Lauren , Lyons B. Casey , David Sarah , Ritchey Matthew D. , Ahmad Farida B. , McNaghten A. D. , Gundlapalli Adi V. , Suthar Amitabh B. 
Published: July 2024

Mortality surveillance systems can have limitations, including reporting delays, incomplete reporting, missing data, and insufficient detail on important risk or sociodemographic factors that can impact the accuracy of estimates of current trends, disease severity, and related disparities across subpopulations. The Centers for Disease Control and Prevention used multiple data systems during the COVID-19 emergency response—line-level case‒death surveillance, aggregate death surveillance, and the National Vital Statistics System—to collectively provide more comprehensive and timely information on COVID-19‒associated mortality necessary for informed decisions. This article will review in detail the line-level, aggregate, and National Vital Statistics System surveillance systems and the purpose and use of each. This retrospective review of the hybrid surveillance systems strategy may serve as an example for adaptive informational approaches needed over the course of future public health emergencies. ( Am J Public Health. 2024;114(10):1071–1080. https://doi.org/10.2105/AJPH.2024.307743 )