bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hubungan Lingkungan Kerja dengan Kepuasan Kerja Perawat di Rumah Sakit Mitra Medika Tahun 2020
Authors: Syaftriani Afina Muharani , Harahap Eki Maryo , Hanim Hizrah 
Published: July 2024

Pelayanan keperawatan menjadi faktor penentu keberhasilan pelayanan kesehatan di rumah sakit, dimana hampir di setiap negara hingga 80% pelayanan diberikan oleh perawat. Tenaga keperawatan memberikan kontribusi yang cukup besar terhadap pelayanan yang diberikan oleh sebuah Rumah Sakit, karena pelayanan keperawatan memberikan pelayanan konstan dan berkesinambungan dengan pelanggan seperti pasien. Tujuan penelitian ini untuk mengetahui hubungan lingkungan kerja dengan kepuasan kerja perawat di rumah sakit Mitra Medika Medan Tahun 2020. Desain Penelitian ini menggunakan survey analitik dengan pendekatan cross sectional. Populasi penelitian ini adalah perawat di rumah sakit Mitra Medika berjumlah 193 responden. jumlah sampel dengan metode pengambilan accidental sampling 66 responden. analisa data yang digunakan yaitu analisa univariat dan analisa bivariat dengan menggunakan uji Chi Square. Hasil penelitian menunjukkan bahwa lingkungan kerja baik 58 responden (87,9%), dan kepuasan kerja perawat puas 53 responden (80,3%). Hasil uji statistik dengan uji Chi-Square ada hubungan lingkungan kerja dengan kepuasan kerja perawat dengan nilai p value = 0,006. Kesimpulan dalam penelitian ini menunjukkan bahwa secara statistik ada hubungan yang signifikan antara lingkungan kerja dengan kepuasan kerja perawat di rumah sakit Mitra Medika Medan Tahun 2020. Disarankan kepada rumah sakit untuk memberikan fasilitas kamar mandi di setiap ruangan perawat sehingga tingkat kepuasan kerja perawat lebih berkualitas.
Faktor yang Berhubungan dengan Tingkat Anemia pada Ibu Hamil Trisemester III di Klinik Siti Hajar
Authors: Ardilla Maya , Haryanti Maria 
Published: July 2024

Anemia merupakan suatu penurunan kadar hemoglobin, hematokrit dan jumlah eritrosit dibawah nilai normal yaitu kurang dari 11 gr/dl.Tujuan: penelitian ini untuk mengetahui faktor yang berhubungan dengan tingkat anemia pada ibu hamil trimester 3 di Klinik Siti Hajar tahun 2020. Metode: desain penelitian ini menggunakan Survei Analitik dengan pendekatan Cross Sectional dan mengunakan uji chi-square. Populasi dalam penenlitian ini adalah pasien anemia berjumlah 30 responden, sedangkan sampel yang digunakan adalah total sampling. Hasil: Berdasarkan hasil analisa dengan menggunakan uji Chi Square test memperlihatkan bahwa nilai signifikan probabilitas (Asymp.Sig) ada hubungan paritas dengan anemia pada ibu hamil dengan nilai p(sig) = 0,003, ada hubungan pemeriksaan kehamilan pada ibu hamil dengan nilai p(sig) = 0,005, ada hubungan pengetahuan dengan anemia pada ibu hamil dengan nilai p(sig) = 0,011, ada hubungan kepatuhan dengan anemia pada ibu hamil dengan nilai p(sig) = 0,028. dalam penelitian ini ada hubungan paritas, pemeriksaan kehamilan, pengetahuan, kepatuhan minum tablet Fe dengan anemia pada ibu hamil trimester 3. Kesimpulan: dalam penelitian ini ada hubungan paritas, pemeriksaan kehamilan, pengetahuan, kepatuhan minum tablet Fe dengan anemia pada ibu hamil trimester 3. Diharapkan kepada ibu hamil untuk memeriksakan kehamilannya dan diupayakan untuk sering cek Hb serta memperhatikan makanan yang di konsumsi selama hamil karena ibu sehat belum tentu kadar Hb nya normal.
Hubungan Lingkungan Kerja dengan Kepuasan Kerja Perawat di Rumah Sakit Mitra Medika Medan
Authors: Mulidan Mulidan , Hanim Hizrah 
Published: July 2024

Pelayanan keperawatan menjadi faktor penentu keberhasilan pelayanan kesehatan di rumah sakit, dimana hampir di setiap negara hingga 80% pelayanan diberikan oleh perawat. Tenaga keperawatan memberikan kontribusi yang cukup besar terhadap pelayanan yang diberikan oleh sebuah Rumah Sakit, karena pelayanan keperawatan memberikan pelayanan konstan dan berkesinambungan dengan pelanggan seperti pasien. Tujuan penelitian ini untuk mengetahui hubungan lingkungan kerja dengan kepuasan kerja perawat di rumah sakit Mitra Medika Medan Tahun 2020. Desain Penelitian ini menggunakan survey analitik dengan pendekatan cross sectional. Populasi penelitian ini adalah perawat di rumah sakit Mitra Medika berjumlah 193 responden. jumlah sampel dengan metode pengambilan accidental sampling 66 responden. analisa data yang digunakan yaitu analisa univariat dan analisa bivariat dengan menggunakan uji Chi Square. Hasil penelitian menunjukkan bahwa lingkungan kerja baik 58 responden (87,9%), dan kepuasan kerja perawat puas 53 responden (80,3%). Hasil uji statistik dengan uji Chi-Square ada hubungan lingkungan kerja dengan kepuasan kerja perawat dengan nilai p value = 0,006. Kesimpulan dalam penelitian ini menunjukkan bahwa secara statistik ada hubungan yang signifikan antara lingkungan kerja dengan kepuasan kerja perawat di rumah sakit Mitra Medika Medan Tahun 2020. Disarankan kepada rumah sakit untuk memberikan fasilitas kamar mandi di setiap ruangan perawat sehingga tingkat kepuasan kerja perawat lebih berkualitas.
Gambaran Tingkat Pengetahuan Cuci Tangan Masyarakat dalam Menghadapi Covid-19 di Dusun II Desa Helvetia
Authors: Mulidan Mulidan , Hanim Hizrah , Bakti Agus 
Published: July 2024

Mencuci tangan dengan sabun adalah salah satu tindakan sanitasi dengan membersihkan tangan dan jari jemari menggunakan air dan sabun oleh manusia untuk menjadi bersih dan memutuskan mata rantai kuman. Mencuci tangan dengan sabun kebersihan tangan dikenal juga sebagai salah satu upaya pencegahan penyakit. Tujuan untuk mengetahui gambaran tingkat pengetahuan cuci tangan masyarakat dalam menghadapi covid-9 di Dusun II Desa Helvetia Tahun 2021. Metode Desain penelitian yang digunakan dalam penelitian ini menggunakan metode desain deskriptif. Populasi dalam penelitian ini seluruh masyarakat yang berada di Dusun II Desa Helvetia dengan jumlah populasi pada bulan januari tahun 2021 – juni tahun 2021 sebanyak 129 orang. Pengambilan sampel yang digunakan dalam penelitian ini adalah dengan cara purposive sampling. Hasil; Dari 56 responden di ketahui bahwa yang memiliki pengetahuan Mencuci Tangan kurang sejumlah 26 (46,4%) responden, yang pengetahuan cukup sejumlah 20 (35,7%) responden, dan yang pengetahuan baik sejumlah 10 (17,9%) responden. Kesimpulan Berdasarkan hasil yang telah dilakukan oleh peneliti mengenai Gambaran Tingkat Pengetahuan Cuci Tangan Masyarakat Dalam Menghadapi Covid-19 Di Dusun II Desa Helvetia Tahun 2021. Bagi responden di harapkan dapat menjadi saran atau bahan tambahan untuk meningkatkan pengetahuan dalam upaya mencegah Covid-19.
Amélie Le Renard (2021) The Western Privilege: Work, Intimacy, and Postcolonial Hierarchies in Dubai
Authors: Kandara Cansu 
Published: July 2024

Review of Western Privilege: Work, Intimacy, and Postcolonial Hierarchies in Dubai by Amélie (Saba) Le Renard (Transl. by Jane Kuntz, Stanford University Press. (256 Pages, Hardcover ISBN: 9781503613843, Paperback ISBN: 9781503629233, Ebook ISBN: 9781503629240)

Western Privilege overlooks a sociological perspective on the Western expats’ hegemony who are the privileged ones in Dubai from a feminist postcolonial perspective. The researcher Amélie Le Renard emphasizes transformations and reproduction of hierarchies that interlink race, nationality, gender, and sexuality. The researcher demonstrates concessions and privileges for the employees and the white collars who have Western passports and non-white employees and working class from other countries. Having a Western European passport reproduces the hierarchical division of labor in favor of getting well-paid, having higher positions, easier career jumping, and redoubling or rapid salary increase for Westerners in the job market, and having more working hours as opposed to getting less paid within resident permit problems for non-Westerners.
Nucleot(s)ide Analogs for Chronic Hepatitis Virus Therapy: A Global Bibliometric Analysis (1986-2022)
Authors: Putri Wahyu Aristyaning , Setiawan Jajar , Sofyantoro Fajar , Priyono Dwi Sendi , Septriani Nur Indah , Mafiroh Wulan Usfi , Siregar Abdul Rahman , Yano Yoshihiko , Wasityastuti Widya 
Published: July 2024

Objectives: This study aimed to analyze the global profile of the nucleotide/nucleoside analogs (NAs) for chronic hepatitis virus therapy-related research.
Background: NAs, which closely resemble the structure of naturally occurring nucleotides/nucleosides, function by disrupting the elongation of the nascent DNA strand. These compounds are considered safe and well-tolerated, as they specifically target viral, but not human, polymerases involved in DNA replication. NAs are crucial in treating viral infections, including hepatitis, and are widely used due to their efficacy and safety. However, a study about trends in NAs for chronic hepatitis therapy-related research was never reported before.
Methods: The NAs for chronic hepatitis therapy-related research bibliometric analysis was performed on articles indexed in the Scopus database from 1986 to 2022.
Results: The total number of articles published worldwide is 2,341 documents, with an annual average of 65 documents. The United States generated the most articles (n = 486), followed by China (n = 454), France (n = 191), and Italy (n = 179). Since 1992, the number of publications has increased dramatically worldwide. Globally, liver cell carcinoma, antiviral therapy, hepatitis B (e) antigen, and alanine aminotransferase are becoming hot research topics in the field.
Conclusions: This study provides a unique composite picture of NAs for chronic hepatitis therapy-related research worldwide and evaluates research productivity from 1986 to 2022. This finding suggests that the prospects for interventions in chronic hepatitis remain promising.
Bangladesh Journal of Medical Science Vol. 23 No. 03 July’24 Page : 747-756
Differential effects of areca nut, tobacco, and lime on oral squamous cell carcinoma progression
Authors: Verma Tarun Prakash , Adhikari Sonali , Kandpal Meenakshi , Jha Hem Chandra 
Published: July 2024

BackgroundConsumption of tobacco and its associated products has been linked with a high incidence of oral cancer in the Indian subcontinent. The present study aims to assess the differential effects of areca nut, tobacco, and slaked lime on the pathogenesis and progression of oral cancer.MethodologyExtracts of areca nut (ANE), tobacco leaf (TLE), and lime water (LWE) were prepared and characterized. Oral keratinocyte cells (BICR10) were treated with the prepared extracts alone and in combinations. Cell apoptosis, necrosis, nuclear aberrations, and transcript expression profiles were assessed to study the cancer pathogenesis.ResultsAn increase in apoptosis and necrosis was observed in the cells treated with ANE and ANE+LWE, while a decrease in apoptosis was observed in cells treated with TLE. We also found a variation in the size of nuclei and an increase in the number of multinuclei in the cells treated with TLE and TLE+LWE. Out of 24 head and neck cancer-related genes, we found significant upregulation in seven genes in ANE, six in ANE+LWE, 13 in TLE, 20 in LWE, and 14 in TLE+LWE treated cells. On pathway enrichment analysis, there were alterations in the “pathways in cancer,” “focal adhesion,” and “amoebiasis.”ConclusionAlthough areca nut has been regarded as a carcinogen, its carcinogenic potential is lesser than tobacco and lime. Moreover, adjunctive use of tobacco and lime along with areca nut may be an essential factor in the onset and progression of oral cancer.
Investigation of differentially expressed genes related to cellular senescence between high-risk and non-high-risk groups in neuroblastoma
Authors: Zhou Xingyu , Wu Yuying , Qin Lan , Zeng Miao , Zhang Mingying , Zhang Jun 
Published: July 2024

ObjectThis study aims to identify differentially expressed genes (DEGs) between high-risk and non-high-risk groups in neuroblastoma (NB), construct a prognostic model, and establish a risk score formula.Materials and methodsThe NB dataset GSE49710 (n = 498) from the GEO database served as the training cohort to select DEGs between high-risk and non-high-risk NB groups. Cellular senescence-related genes were obtained from the Aging Atlas database. Intersection genes from both datasets were identified as key genes of cellular senescence-related genes (SRGs). A prognostic model was constructed using Univariate Cox regression analysis and the Lasso algorithm with SRGs. Validation was performed using the E-MTAB-8248 cohort (n = 223). The expression levels of AURKA and CENPA were evaluated via RT-qPCR in two clinical NB sample groups.ResultsEight SRGs were identified, and a prognostic model comprising five genes related to cellular senescence was constructed. AURKA and CENPA showed significant expression in clinical samples and were closely associated with cellular senescence.ConclusionThe prognostic model consisted with five cellular senescence related genes effectively predicts the prognosis of NB patients. AURKA and CENPA represent promising targets in NB for predicting cellular senescence, offering potential insights for NB therapy.
Quantification of soil organic carbon: the challenge of biochar-induced spatial heterogeneity
Authors: Lotz Simon , Bucheli Thomas D. , Schmidt Hans-Peter , Hagemann Nikolas 
Published: July 2024

IntroductionSoil organic carbon (SOC) content can vary significantly across a given plot. Therefore, a representative sampling is a prerequisite to obtain meaningful results from analysis and of utter importance when SOC quantification is used to quantify (temporary) carbon dioxide removal (CDR). However, certain management practices aiming to increase SOC further increase the level of heterogeneity and may challenge representative sampling schemes. This includes concentrated root-zone application of biochar, which immediately increases SOC with the input of biochar-C and may promote the local enrichment of non-biochar SOC over time.MethodsHere, we used numerical modelling to quantify the number of single sampling points (soil cores) needed to achieve a representative sample of biochar-C and total SOC on a plot after application of biochar in rows, e.g., for growing vegetables, or in the circumference of trees in agroforestry systems.ResultsAfter row application of 5 t ha−1 biochar in soil with rather low SOC content (26 t ha−1), 140 soil cores (per 0.25 ha plot) where necessary to achieve representative sampling of C-stocks (±5% error) in 90% of the repeated sampling simulation cases. Compared to realistic and cost-effective soil sampling scenarios in agronomic practice, we conclude that concentrated root zone application of biochar makes representative sampling for quantification of SOC in soils with low baseline C-stocks virtually impossible.DiscussionThis finding calls into question the soil-sampling and SOC-analysis-based (“result-based”) monitoring of SOC as a (temporary) CDR when biochar might have been applied. Considering the rapid scaling of biochar production and use in agriculture, this is a considerable challenge for SOC certification. Instead, action-based incentives, rewarding farmers for carrying out specific practices, could be applied to promote carbon farming practices.
An experimental research of the influence on critical heat flux of a rod bundle under certain inlet temperatures
Authors: Duan Minghui , Zhao Minfu , Wei Junhan , Xu Yongwang 
Published: July 2024

Critical heat flux (CHF) is one of the most concerned thermal hydraulic phenomena in reactor safety analysis. It involves complex two-phase flow heat transfer mechanism, and has not been fully understood, so the prediction of critical heat flux mainly depends on CHF correlations obtained under limited experimental conditions. At present, CHF correlations are generally developed with pressure, mass flux and quality as key independent variables. And correspondingly, the test matrix of a CHF test consists of the above parameters. However, it is impossible to perform CHF tests accurately according to the predetermined quality. In CIAE, a CHF experimental research of a 5 × 5 uniformly heated rod bundle has been carried out. In the experiment, the inlet temperature of the test section was directly taken as a parameter in the test matrix. The CHF data were achieved by stepwise increasing the heating power. The test conditions covered the pressure of 2.8–15.5 MPa, the mass flux of 845–3533 kg/(m2·s), and the inlet temperature of 100°C–300°C. The test data have been analyzed to obtain the thermal-hydraulic parameter influences on CHF by taking the inlet temperature as a variable. The results indicated that, within the test condition range, under the same inlet temperatures, CHF was hardly affected by pressure, and linearly increased with the increasing mass flux. With the increase of inlet temperature, the enhancement of CHF with the increasing mass flux gradually weakens. And CHF was linearly decreased with the increasing inlet temperature under the same mass flux. By contrast, the parameter influences on CHF were more complex by taking the local quality as a variable. According to the research, it can be concluded that, it has an advantage of simplifying the CHF correlation form to take the inlet temperature of the test section as a variable parameter. The research can provide new ideas for CHF experiment, data analysis and correlation development.
Preimplantation genetic testing for complex chromosomal rearrangements: clinical outcomes and potential risk factors
Authors: Liu Dun , Chen Chuangqi , Huang Qianwen , Dong Yunqiao , Xu Liqing , Dong Mei , Zhu Zhenghong , Huang Li , Wang Fang , Zhang Lijia , Zhang Xiqian , Liu Fenghua 
Published: July 2024

ObjectiveComplex chromosome rearrangements (CCR) are rare structural abnormalities involving at least three breakpoints, categorized into three types based on their structure: type A (three-way rearrangements), type B (double two-way translocations), and type C (exceptional CCR). However, thus far, limited data exists on preimplantation genetic testing for chromosomal structural rearrangements (PGT-SR) in CCR carriers. This study aims to evaluate the clinical outcomes and influencing factors of PGT-SR in couples with CCR.MethodsFifteen couples with unique CCR recruited from 793 couples following PGT-SR between January 2017 and May 2023. In addition, a total of 54 CCR cases, 39 previously reported as well as 15 newly added, were included in the analysis of factors associate with normal/balanced embryos.ResultsA total of 100 blastocysts were biopsied and analyzed in 15 CCR couples after 17 PGT-SR cycles, with 16.0% being euploid, 78.0% aneuploid and 6.0% mosaic. 11 normal/balanced embryos and one mosaic embryo were transferred, resulting in eight live births. Furthermore, based on the combined data from 54 CCR carriers, the proportion of normal/balanced embryos was 10.8%, with a significant decrease observed among female carriers compared to male heterozygotes (6.5% vs. 15.5%, p = 0.002). Type B exhibited the lowest rate of euploid embryos at only 6.7%, followed by type A at 11.6% and type C at 14.0%, although the differences were not significant (p = 0.182). After completing the multivariate generalized estimating equation (GEE) analysis, type B (p = 0.014) and female carrier (p = 0.002) were identified as independent risk factors for fewer euploid embryos.ConclusionThe occurrence of balanced CCR in patients with reproductive abnormalities may be more frequent than we expected. Despite the proportion of normal/balanced embryos being significantly low, which can be influenced by CCR type and carrier’s sex, PGT-SR may improve the reproductive outcomes among CCR cases. These findings can optimize the clinical management and genetic counseling of CCR carriers seeking assisted reproductive technology (ART).
Current status and future directions of nanovaccine for cancer: a bibliometric analysis during 2004-2023
Authors: Hou Yuhui , Li Yue , Zhang Youao , Zhang Juan , Wu Dinglan 
Published: July 2024

BackgroundNanovaccine treatment is an exciting area of research in immunology and personalized medicine, holding great promise for enhancing immune responses and targeting specific diseases. Their small size allows efficient uptake by immune cells, leading to robust immune activation. They can incorporate immune-stimulating molecules to boost vaccine efficacy. Therefore, nanovaccine can be personalized to target tumor-specific antigens, activating the immune system against cancer cells. Currently, there have been ample evidence showing the effectiveness and potential of nanovaccine as a treatment for cancer. However, there was rare bibliometric analysis of nanovaccine for cancer. Here we performed a bibliometric and visual analysis of published studies related to nanovaccine treatment for cancer, providing the trend of future development of nanovaccine.MethodsWe collected the literatures based on the Web of Science Core Collection SCI-Expanded database. The bibliometric analysis was performed via utilizing visualization analysis tools VOSviewer, Co-Occurrence (COOC), Citespace, Bibliometrix (R-Tool of R-Studio), and HitCite.ResultsA total of 517 literatures were included in this study. China is the country with the most publications and the highest total local citation score (TLCS). The Chinese Academy of Sciences holds the largest research count in this field and the most prolific author is Deling Kong from Nankai University. The most prominent journal for publishing in this area is Biomaterials. The researches mainly focus on the therapeutic process of tumor nanovaccines, the particle composition and the application of nanovaccines, suggesting the potential hotspots and trends of nanovaccine.ConclusionIn this study, we summarized the characteristics and variation trends of publications involved in nanovaccine, and categorized the most influential countries, institutions, authors, journals, hotspots and trends regarding the nanovaccine for cancer. With the continuous development of nanomaterials and tumor immunotherapy, nanovaccine for cancer provides a research field of significant clinical value and potential application.