bluuebunny/crossref_metadata_2025_split huggingface dataset:
An efficient power management scheme with SDMA for IEEE 802.15.3 WPANs
Authors: Wang Neng‐Chung , Wen Chih‐Cheng 
Published: July 2013

SUMMARYIEEE 802.15.3 is devised for short‐distance wireless connectivity within a wireless personal area network (WPAN). In WPANs, a power management (PM) mechanism is used for power saving. The PM enables devices to sleep for one or more superframes in order to conserve power. Space division multiple access (SDMA) is a new technology to optimize performance of current and future mobile communication systems. In this paper, we propose an SDMA‐based PM scheme, called enhanced min‐degree searching (EMDS) for WPANs. EMDS orders the streams among multiple devices to minimize the total wake‐up times. In this scheme, every device that can transmit data at the same time is checked using the SDMA. The total wake‐up times will be reduced substantially if the majority of the devices can transmit data at the same time. Simulation results show that the performance of the proposed EMDS outperforms that of the existing approaches. Copyright © 2013 John Wiley & Sons, Ltd.
Fat sensitivity in humans: oleic acid detection threshold is linked to saliva composition and oral volume
Authors: Poette J. , Mekoué J. , Neyraud E. , Berdeaux O. , Renault A. , Guichard E. , Genot C. , Feron G. 
Published: July 2013

ABSTRACTFat perception is assumed to result, at least in part, from in‐mouth non‐esterified fatty acids (NEFAs) detection. The aim of this study was to better understand how human oral physiology may govern the sensory sensitivity to NEFAs. For this purpose, the detection thresholds for oleic acid were determined for 17 human subjects with highly varying salivary and oral characteristics, and the thresholds were related to their oral and salivary characteristics with conventional and multidimensional data analysis. These thresholds were tested on a dairy oil‐in‐water emulsion that was specifically designed to avoid biases caused by differences in the initial structure of the emulsion as a function of oleic acid concentration. The emulsion was judged to be rather acceptable compared with model emulsions and commercial emulsified dairy foods. Twelve oleic acid concentrations, ranging from 0.00028% to 0.16% (w/w) in the emulsion, were tested with the ascending series three‐alternate forced‐choice method with nose‐clips (WNC) or without nose‐clips (WoNC). The oleic acid WNC and WoNC thresholds were 0.09% w/w and 0.063% w/w, respectively, and hypersensitive and hyposensitive subjects were identified. Partial least squares and analysis of variance indicated that the WNC threshold is positively correlated to both the lipolytic activity of saliva and the oral volume, whereas the WoNC threshold is positively correlated to the saliva antioxidant status and negatively correlated to its protein amount and lysozyme activity. This study supports the hypothesis that NEFAs are detected in the oral cavity in humans and provides new insights on the oral physiological characteristics that may play important roles in fat detection. Copyright © 2013 John Wiley & Sons, Ltd.
Smad‐interacting protein 1 affects acute and tonic, but not chronic pain
Authors: Pradier B. , Jeub M. , Markert A. , Mauer D. , Tolksdorf K. , Van de Putte T. , Seuntjens E. , Gailus‐Durner V. , Fuchs H. , Hrabě de Angelis M. , Huylebroeck D. , Beck H. , Zimmer A. , Rácz I. 
Published: July 2013

AbstractBackgroundSmad‐interacting protein 1 (also named Zeb2 and Zfhx1b) is a transcription factor that plays an important role in neuronal development and, when mutated, causes Mowat–Wilson syndrome (MWS). A corresponding mouse model carrying a heterozygous Zeb2 deletion was comprehensively analysed in the German Mouse Clinic. The most prominent phenotype was the reduced pain sensitivity. In this study, we investigated the role of Zeb2 in inflammatory and neuropathic pain.MethodsFor this, we tested mutant Zeb2 animals in different models of inflammatory pain like abdominal constriction, formalin and carrageenan test. Furthermore, we studied the pain reactivity of the mice after peripheral nerve ligation. To examine the nociceptive transmission of primary sensory dorsal root ganglia (DRG) neurons, we determined the neuronal activity in the spinal dorsal horn after the formalin test using staining of c‐Fos. Next, we characterized the neuronal cell population in the DRGs and in the sciatic nerve to study the effect of the Zeb2 mutation on peripheral nerve morphology.ResultsThe present data show that Zeb2 is involved in the development of primary sensory DRG neurons, especially of C‐ and Aδ fibres. These alterations contribute to a hypoalgesic phenotype in inflammatory but not in neuropathic pain in these Zeb2+/− mice.ConclusionOur data suggest that the under‐reaction to pain observed in MWS patients results from a reduced responsivity to nociceptive stimulation rather than an inability to communicate discomfort.
3D‐ultramicroscopy utilizing aspheric optics
Authors: Saghafi Saiedeh , Becker Klaus , Hahn Christian , Dodt Hans‐Ulrich 
Published: July 2013

AbstractUsing a combination of achromatic aspheric optical elements and achromatic cylindrical lenses, we developed an improved laser light sheet generator for two‐side illumination ultramicroscopy. This light sheet generator has a much longer Rayleigh range, a more uniform spatial intensity distribution along x ‐, y ‐ and z‐axis, and reduced aberrations than the standard system consisting of a slit aperture and a single cylindrical lens, which is commonly used in light sheet microscopy. As there is no truncation of the beam by a slit aperture in our design the laser energy is used more efficiently. Applying this light sheet generator to ultramicroscopy of chemically cleared biological samples, such as Drosophila, dissected mouse hippocampi, and entire mouse brains, we achieved a markedly improved resolution of fine details. (© 2014 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
The 18.6‐year nodal tidal cycle and the bi‐decadal precipitation oscillation over the plains to the east of subtropical Andes, South America
Authors: Agosta Eduardo Andres 
Published: July 2013

ABSTRACTThis work shows statistical evidence for lunar nodal cycle influence on the low‐frequency summer rainfall variability over the plains to the east of subtropical Andes, in South America, through long‐term sea surface temperature (SST) variations induced by the nodal amplitude of diurnal tides over southwestern South Atlantic (SWSA). In years of strong (weak) diurnal tides, tide‐induced diapycnal mixing makes SST cooler (warmer) together with low (high) air pressures in the surroundings of the Malvinas/Falklands Islands in the SWSA, possibly through mean tropospheric baroclinicity variations. As the low‐level tropospheric circulation anomalies directly affect the interannual summer rainfall variability, such an influence can be extended to the bi‐decadal variability present in the summer rainfall owing to the nodal modulation effect observed in the tropospheric circulation. The identification of the nodal periodicity in the summer rainfall variability is statistically robust.
Advanced Functional Polymers for Increasing the Stability of Organic Photovoltaics
Authors: Bundgaard Eva , Helgesen Martin , Carlé Jon E. , Krebs Frederik C. , Jørgensen Mikkel 
Published: July 2013

AbstractThe development of new advanced polymers for improving the stability of OPV is reviewed. Two main degradation pathways for the OPV active layer are identified: photochemically initiated reactions primarily starting in the side chains and morphological changes that degrade the important nanostructure. Chemical units can be introduced that impart an increased stability. Similarly, the morphological degradation of the optimal nanostructure can be reduced. Active polymers and blends with acceptor material are used to create nanoparticle links with controlled size. Most of these advanced polymers and processing methods have only been utilized in small‐scale devices prepared by standard techniques such as spin coating, but a few cases of roll‐to‐roll processed solar cells with heat‐cleaved side chains are discussed.magnified image
Inhibitions of epithelial to mesenchymal transition and cancer stem cells‐like properties are involved in miR‐148a‐mediated anti‐metastasis of hepatocellular carcinoma
Authors: Yan Han , Dong Xiaogang , Zhong Xiaoqin , Ye Jing , Zhou Yun , Yang Xiaojun , Shen Jian , Zhang Jianping 
Published: July 2013

AbstractThe epithelial–mesenchymal transition (EMT) and acquisition of cancer stem cells (CSCs)‐like properties are essential steps in the metastasis and postsurgical recurrence of hepatocellular carcinomas (HCCs). The molecular mechanisms involved, however, remain obscure. As determined by an miRNA microarray analysis, there was lower expression of miR‐148a in poorly differentiated HCC tissues relative to well‐differentiated HCC tissues. MHCC97H and MHCC97L (HCC cells with migratory capacity) and HCC tissues with various differentiation status were selected for further investigation. The results showed that miR‐148a levels inversely correlated with the differentiation status of HCC tissues. In MHCC97H and MHCC97L cells, over‐expression of miR‐148a blocked the EMT process, attenuated the expression of CD90 and CD44 (biomarkers for liver cancer stem cells), and inhibited their migratory capacity. Via TargetScan and microRNA.org algorithms, miR‐148a was predicted to bind to the Wnt1 mRNA 3′‐UTR. Wnt1 was confirmed as a target gene of miR‐148a in HCC cells, and the Wnt signal pathway was determined to be involved in the miR‐148a‐mediated inhibition of EMT and CSCs‐like properties of MHCC97H cells. Moreover, the expression of miR‐148a in nonmetastatic HCC tissues was higher than that in metastatic HCC tissues. The results suggest that miR‐148a inhibits the metastasis of HCCs by blocking EMT and CSCs‐like properties through effects on the Wnt signaling pathway. © 2013 Wiley Periodicals, Inc.
Pelvic floor muscle training in women with stress urinary incontinence causes hypertrophy of the urethral sphincters and reduces bladder neck mobility during coughing
Authors: McLean Linda , Varette Kevin , Gentilcore‐Saulnier Evelyne , Harvey Marie‐Andree , Baker Kevin , Sauerbrei Eric 
Published: July 2013

AbstractAimsThe purpose of this study was to determine the effect of a 12‐week pelvic floor muscle (PFM) training program on urethral morphology and mobility in women with stress urinary incontinence (SUI).MethodsForty women with SUI were randomly assigned to one of two groups: the treatment group received 12 weekly physiotherapy sessions during which they learned how to properly contract their pelvic floor muscles (PFMs) and a home exercise program was prescribed, reviewed, and progressed; the control group received no treatment. Before and after the 12‐week study period, ultrasound imaging was used to evaluate bladder neck position and mobility during coughing and Valsalva maneuver in supine and in standing, as well as urethral morphology. Secondary outcome measures included a 3‐day bladder diary, 30‐min pad test, the Incontinence Impact Questionnaire (IIQ‐7) and the Urogenital Distress Inventory (UDI‐6).ResultsThe women in the treatment group demonstrated reduced bladder neck mobility during coughing and increased cross‐sectional area of their urethra after as compared to before the training. These changes were not evident in the control group. No differences in the resting position of the bladder neck or in bladder neck excursion during Valsalva maneuver were noted in either group. Concomitantly the women in the treatment group demonstrated significant improvements in the 3‐day bladder diary and IIQ‐7 after the PFM training and improved significantly more than the control group.ConclusionPhysiotherapist‐supervised PFM training reduces bladder neck motion during coughing, and results in hypertrophy of the urethral sphincter in women who present with SUI. Neurourol. Urodynam. 32:1096–1102, 2013. © 2013 Wiley Periodicals, Inc.
Feasibility of Implementing a Comprehensive Warfarin Pharmacogenetics Service
Authors: Nutescu Edith A. , Drozda Katarzyna , Bress Adam P. , Galanter William L. , Stevenson James , Stamos Thomas D. , Desai Ankit A. , Duarte Julio D. , Gordeuk Victor , Peace David , Kadkol ShriHari S. , Dodge Carol , Saraf Santosh , Garofalo John , Krishnan Jerry A. , Garcia Joe G. N. , Cavallari Larisa H. 
Published: July 2013

Study ObjectiveTo determine the procedural feasibility of a pharmacist‐led interdisciplinary service for providing genotype‐guided warfarin dosing for hospitalized patients newly starting warfarin.DesignProspective observational study.SettingA 438‐bed tertiary care hospital affiliated with a large academic institution.PatientsEighty patients who started warfarin therapy and were managed by a newly implemented pharmacogenetics service.InterventionAll patients received routine warfarin genotyping and clinical pharmacogenetics consultation.Measurements and Main ResultsThe primary outcomes were percentage of genotype‐guided dose recommendations available prior to the second warfarin dose and adherence of the medical staff to doses recommended by the pharmacogenetics service. Of 436 genotype orders placed during the first 6 months of the service, 190 (44%) were deemed appropriate. For the 80 patients on the service who consented to data collection, 76% of the genotypes were available prior to the second warfarin dose. The median (range) time from genotype order to genotype result was 26 hours (7–80 hrs), and the time to genotype‐guided dose recommendation was 30 hours (7–80 hrs). A total of 73% of warfarin doses ordered by the medical staff were within 0.5 mg of the daily dose recommended by the pharmacogenetics consult service.ConclusionProviding routine genotype‐guided warfarin dosing supported by a pharmacogenetics consult service is feasible from a procedural standpoint, with most genotypes available prior to the second warfarin dose and good adherence to genotype‐guided dose recommendations by the medical staff.
Polymer entanglement loss in extensional flow: Evidence from electrospun short nanofibers
Authors: Greenfeld Israel , Zussman Eyal 
Published: July 2013

ABSTRACTHigh strain rate extensional flow of a semidilute polymer solution can result in fragmentation caused by polymer entanglement loss, evidenced by appearance of short nanofibers during electrospinning. The typically desired outcome of electrospinning is long continuous fibers or beads, but, under certain material and process conditions, short nanofibers can be obtained, a morphology that has scarcely been studied. Here we study the conditions that lead to the creation of short nanofibers, and find a distinct parametric space in which they are likely to appear, requiring a combination of low entanglement of the polymer chains and high strain rate of the electrospinning jet. Measurements of the length and diameter of short nanofibers, electrospun from PMMA dissolved in a blend of CHCl3and DMF, confirm the theoretical prediction that the fragmentation of the jet into short fibers is brought about by elastic stretching and loss of entanglement of the polymer network. The ability to tune nanofiber length, diameter and nanostructure, by modifying variables such as the molar mass, concentration, solvent quality, electric field intensity, and flow rate, can be exploited for improving their mechanical and thermodynamic properties, leading to novel applications in engineering and life sciences. © 2013 Wiley Periodicals, Inc. J. Polym. Sci., Part B: Polym. Phys.2013,51, 1377–1391
Lifestyle Migration to the North: Dutch Families and the Decision to Move to Rural Sweden
Authors: Eimermann Marco 
Published: July 2013

AbstractLifestyle migration is part of an ongoing quest for a better way of life. More or less affluent migrants moving to a destination with a perceived better climate are studied in the context of social rather than economic motivations. This paper focuses on Dutch families and their decision to move to the rural municipality of Hällefors in the Bergslagen area, Sweden. Such a Nordic destination, actively attracting migrants, has not previously been investigated in the context of lifestyle migration. The purpose of the paper is to examine what factors contribute to the decision to move. The research questions are the following: what are the socio‐demographic characteristics of the migrating families? What meanings do the migrants attach to their work environments and places of residence prior to moving? What motivations and expectations have shaped the decision to move? These questions are addressed through an interview study. Results show that the adult family members were mainly born in the late 1950s or in the 1960s. The children were born in the 1990s and early 21st century. According to most respondents, effects of overpopulation and rapid urbanisation, both felt on the work floor and in the living environment, became a serious trigger to leave the Netherlands. Differences between the families consider the character of occupations (within or outside the creative industries) and the length of the decision process. In contrast to some other lifestyle migrant populations, families in this study considered returning as part of their ongoing quest. Copyright © 2013 John Wiley & Sons, Ltd.
Adaptive iterative learning control for coordination of second‐order multi‐agent systems
Authors: Li Jinsha , Li Junmin 
Published: July 2013

SUMMARYIn this paper, an efficient framework is proposed to the consensus and formation control of distributed multi‐agent systems with second‐order dynamics and unknown time‐varying parameters, by means of an adaptive iterative learning control approach. Under the assumption that the acceleration of the leader is unknown to any follower agents, a new adaptive auxiliary control and the distributed adaptive iterative learning protocols are designed. Then, all follower agents track the leader uniformly on [0,T] for consensus problem and keep the desired distance from the leader and achieve velocity consensus uniformly on [0,T] for the formation problem, respectively. The distributed multi‐agent coordinations performance is analyzed based on the Lyapunov stability theory. Finally, simulation examples are given to illustrate the effectiveness of the proposed protocols in this paper.Copyright © 2013 John Wiley & Sons, Ltd.
Super‐Resolution Nonlinear Photothermal Microscopy
Authors: Nedosekin Dmitry A. , Galanzha Ekaterina I. , Dervishi Enkeleda , Biris Alexandru S. , Zharov Vladimir P. 
Published: July 2013

AbstractSuper‐resolution fluorescence microscopy enables imaging of fluorescent structures beyond the diffraction limit. However, this technique cannot be applied to weakly fluorescent cellular components or labels. As an alternative, photothermal microscopy based on nonradiative transformation of absorbed energy into heat has demonstrated imaging of nonfluorescent structures including single molecules and ~1‐nm gold nanoparticles. However, previously photothermal imaging has been performed with a diffraction‐limited resolution only. Herein, super‐resolution, far‐field photothermal microscopy based on nonlinear signal dependence on the laser energy is introduced. Among various nonlinear phenomena, including absorption saturation, multiphoton absorption, and signal temperature dependence, signal amplification by laser‐induced nanobubbles around overheated nano‐objects is explored. A Gaussian laser beam profile is used to demonstrate the image spatial sharpening for calibrated 260‐nm metal strips, resolving of a plasmonic nanoassembly, visualization of 10‐nm gold nanoparticles in graphene, and hemoglobin nanoclusters in live erythrocytes with resolution down to 50 nm. These nonlinear phenomena can be used for 3D imaging with improved lateral and axial resolution in most photothermal methods, including photoacoustic microscopy.
Factors that contribute to Japanese university students' evaluations of the attractiveness of characters
Authors: Nosu Kiyoshi , Tanaka Mai 
Published: July 2013

AbstractThis paper describes quantitative evaluations of existing characters by Japanese university students and a statistical analysis with the aim of identifying factors that contribute to the attractiveness of the characters. Both male and female students indicated that they like characters that are flawed in some way and are not merely cute. However, male and female students also showed different preferences. Male students prefer interesting characters with an appearance that contradicts their personality/behavior, whereas female students prefer relaxed and doodling characters with a body shape that comforts them. © 2013 Institute of Electrical Engineers of Japan. Published by John Wiley & Sons, Inc.
A Glance on Pentacarbonylrhenate(‐I) [Re(CO)5]– and on the (umgepolte) Pentacarbonylrhenium(+I) Cation [Re(CO)5]+ [as Re(CO)5FBF3] and their Reactions
Authors: Beck Wolfgang 
Published: July 2013

AbstractAbstract. Attention is given to reactions of the strongly nucleophilic [Re(CO)5]– and of the electrophilic Re(CO)5+ with the weakly bonded BF4– anion.
Associations between thyroid hormones and serum metabolite profiles in an euthyroid population
Authors: Jourdan Carolin , Linseisen Jakob , Meisinger Christa , Petersen Ann-Kristin , Gieger Christian , Rawal Rajesh , Illig Thomas , Heier Margit , Peters Annette , Wallaschofski Henri , Nauck Matthias , Kastenmüller Gabi , Suhre Karsten , Prehn Cornelia , Adamski Jerzy , Koenig Wolfgang , Roden Michael , Wichmann H-Erich , Völzke Henry 
Published: July 2013

Abstract
The aim was to characterise associations between circulating thyroid hormones—free thyroxine (FT4) and thyrotropin (TSH)—and the metabolite profiles in serum samples from participants of the German population-based KORA F4 study. Analyses were based on the metabolite profile of 1463 euthyroid subjects. In serum samples, obtained after overnight fasting (≥8), 151 different metabolites were quantified in a targeted approach including amino acids, acylcarnitines (ACs), and phosphatidylcholines (PCs). Associations between metabolites and thyroid hormone concentrations were analysed using adjusted linear regression models. To draw conclusions on thyroid hormone related pathways, intra-class metabolite ratios were additionally explored. We discovered 154 significant associations (Bonferroni p < 1.75 × 10−04) between FT4 and various metabolites and metabolite ratios belonging to AC and PC groups. Significant associations with TSH were lacking. High FT4 levels were associated with increased concentrations of many ACs and various sums of ACs of different chain length, and the ratio of C2 by C0. The inverse associations observed between FT4 and many serum PCs reflected the general decrease in PC concentrations. Similar results were found in subgroup analyses, e.g., in weight-stable subjects or in obese subjects. Further, results were independent of different parameters for liver or kidney function, or inflammation, which supports the notion of an independent FT4 effect. In fasting euthyroid adults, higher serum FT4 levels are associated with increased serum AC concentrations and an increased ratio of C2 by C0 which is indicative of an overall enhanced fatty acyl mitochondrial transport and β-oxidation of fatty acids.