bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gene expression analysis in allergology: the prediction of Hymenoptera venom allergy severity and treatment efficacy
Authors: Niedoszytko Marek , Gruchała‐Niedoszytko Marta , Jassem Ewa 
Published: October 2013

AbstractInsect venom allergy (IVA) may result in the most severe systemic reactions seen in allergology. The only potentially curative treatment option is venom immunotherapy (VIT) over 3 to 5 years. This treatment is effective in more than 90% of subjects but no reliable predictors of VIT effectiveness exist. Sting challenge with a living insect can be performed to assess the effectiveness of VIT: the predictive value of sting challenge can be highly sensitive in patients with honeybee venom allergy whereas in yellow jacket allergy, a negative result can be reliable if the challenge has been repeated at least 3 times.The analysis of gene expression may be a step towards personalized venom immunotherapy assessing the effectiveness of treatment, the minimal required time for VIT and the persistence of long term tolerance induced by the treatment. Recent studies have enabled construction of a predictive model that could potentially be used in clinical practice to assess the efficacy of insect venom immunotherapy. A set of 69 genes that may be responsible for long‐term protection was identified. Further analysis of the previously identified 6 transcripts make up the 18 gene predictive peripheral blood showed differences in patients treated with IVA. Further studies are needed to investigate the usefulness of gene expression analysis and other markers in the prediction of VIT effectiveness.
Development and validation of RP-HPLC-PDA method for the quantification of eugenol in developed nanoemulsion gel and nanoparticles
Authors: Pramod Kannissery , Ilyas Ura Kottil , Kamal Yoonuskunju Thajudeenkoya , Ahmad Sayeed , Ansari Shahid Hussain , Ali Javed 
Published: October 2013

Abstract

Background
Eugenol is a potent phytochemical, and a plethora of delivery systems for this bioactive agent is being developed. Reversed-phase high-pressure liquid chromatography equipped with photodiode array detector (RP-HPLC-PDA) method is very useful in the quantification of the phytochemicals.

Methods
The RP-HPLC-PDA system with C18 reversed-phase column (250???4.6?mm, particle size 5??m) was used in this study. Acetonitrile and water in 1:1 (v/v) ratio was chosen as the mobile phase under a column temperature of 25?C. The detection wavelength was set at 280?nm with a flow rate of 1?mL/min. Method validation was performed according to the International Conference on Harmonization guidelines.

Results
HPLC method for the quantification of eugenol was successfully developed and validated. The method was validated in terms of linearity and range, accuracy, precision, specificity, robustness, detection limit, and quantitation limit.

Conclusions
The developed RP-HPLC-PDA could be successfully employed for the quantification of eugenol in nanoemulsion gel and nanoparticles.
The N-Chlorination of Primary Amines Using FeCl3 and m-CPBA
Authors: Liu Jia , Xu Junchao , Ren Jiangmeng , Zeng Bu-Bing 
Published: October 2013

Abstract
A simple and effective method for the synthesis of N,N-dichloroamines from primary amines was conducted successfully with m-CPBA as oxidant and FeCl3 as chlorine source at 0 °C. Moreover, N,N-dichloroamines could be converted into nitriles or N-chloroimines in good yields.
Don't Ask Me If You Will Not Listen: The Dilemma of Consultative Participation
Authors: Corgnet Brice , Hernán González Roberto 
Published: October 2013

We study the effect of consultative participation in an experimental principal–agent game, where the principal can consult the agent's preferred option regarding the cost function of the transfer to be implemented in the final stage of the game. We show that consulting the agent was beneficial to principals as long as they followed the agent's choice. Ignoring the agent's choice was detrimental to the principal because it engendered negative emotions and low levels of transfers. Nevertheless, the majority of principals were reluctant to change their mind and adopt the agent's proposal. Our results suggest that the ability to change one's own mind is an important dimension of managerial success.Data, as supplemental material, are available at http://dx.doi.org/10.1287/mnsc.2013.1786 .This paper was accepted by Teck-Hua Ho, behavioral economics.
Particle Breakage of Cement Ellipsoid Aggregate—Part I: Triaxial Compression Tests
Authors: Zhang Bing-yin , Jie Yu-xin , Kong De-zhi 
Published: October 2013

Abstract
Cement ellipsoid aggregate was adopted to simulate rockfill materials in laboratory tests. The specimen was prepared by mixing cement ellipsoids of four diameters in a particular ratio. Triaxial compression tests and isotropic compression tests were then conducted to investigate the macroscopic stress–strain relationship of the aggregate, and the crushing characteristics of the cement ellipsoids. The particle size distributions were analyzed after testing. No particle breakage occurred during the isotropic compression tests or the unloading–reloading process of the triaxial compression tests; this implied that breakage of the cement ellipsoids mainly occurs during the shearing process of loading. Sieving analysis showed that the sizes of the larger particles did not change much; crushing mainly produced small particles and, thus, changed the particle size distribution.
Whole Salivary Interleukin‐6 and Matrix Metalloproteinase‐8 Levels in Patients With Chronic Periodontitis With and Without Prediabetes
Authors: Javed Fawad , Ahmed Hameeda Bashir , Saeed Anwar , Mehmood Abid , Bain Crawford 
Published: October 2013

Background: The cytokine profile in unstimulated whole saliva (UWS) of patients with prediabetes and chronic periodontitis (CP) remains uninvestigated. The aim of this study is to assess interleukin (IL)‐6 and matrix metalloproteinase (MMP)‐8 levels in UWS of patients with CP with and without prediabetes.Methods: Eighty‐eight males (aged 39 to 51 years) were divided into three groups: group 1: 28 patients with CP and prediabetes; group 2: 30 patients with CP and without prediabetes; and group 3: 30 controls. Fasting blood glucose (FBG) and hemoglobin A1c (HbA1c) levels, periodontal parameters (plaque index, bleeding on probing, probing depth, attachment loss, and marginal bone loss), and number of missing teeth were recorded. UWS samples were collected, and UWS flow rate (UWSFR) was measured. IL‐6 and MMP‐8 were measured in UWS using enzyme‐linked immunosorbent assay. P values <0.05 were considered statistically significant.Results: Mean FBG and HbA1c levels were significantly higher in group 1 (119.3 ± 3.1 mg/dL and 6.1% ± 0.2%) than group 2 (80.1 ± 3.5 mg/dL and 4.8% ± 0.5%; P <0.001) and group 3 (75.3 ± 2.2 mg/dL and 4.3% ± 0.2%; P <0.05). UWSFR was significantly higher in groups 2 (0.53 ± 0.1 mL/minute; P <0.05) and 3 (0.51 ± 0.1 mL/minute; P <0.01) than group 1 (0.33 ± 0.05 mL/minute). Periodontal parameters were worse in group 1 (P <0.05) and group 2 (P <0.05) than group 3. There was no difference in periodontal parameters, numbers of missing teeth, or salivary IL‐6 and MMP‐8 levels between patients in groups 1 and 2.Conclusion: Salivary IL‐6 and MMP‐8 levels are elevated in patients with CP with and without prediabetes.
The Influence of Auditor and Client Section 404 Processes on Remediation of Internal Control Deficiencies at All Levels of Severity
Authors: Graham Lynford , Bedard Jean C. 
Published: October 2013

SUMMARY
This paper examines remediation of Sarbanes-Oxley Section 404 internal control deficiencies (ICDs) at all levels of severity, before the balance sheet date. While a number of studies investigate remediation of publicly disclosed material weaknesses (MWs), the activity we study takes place out of public view and occurs among companies with both clean and adverse Section 404 opinions. Using data provided by multiple auditing firms, we find that about one-fourth of detected ICDs are remediated before year-end, leaving many uncorrected. We model remediation activity with direct measures of company and auditor Section 404 processes not available to prior research. Model results show that companies' effective information technology integration and early start to control testing are positively associated with remediation. In contrast, remediation is negatively associated with discovery by auditors, discovery by substantive tests, and related financial misstatements. Following prior research on MWs, we also observe that ICD remediation is less likely for smaller companies with greater financial risk, and for certain entity-level control problems.
Glycemic Exposure and Blood Pressure Influencing Progression and Remission of Diabetic Retinopathy
Authors: Liu Yiyuan , Wang Minghui , Morris Andrew D. , Doney Alex S.F. , Leese Graham P. , Pearson Ewan R. , Palmer Colin N.A. 
Published: October 2013

OBJECTIVE
This study sought to investigate the progression and regression of diabetic retinopathy (DR) and the effects of population risk factors on the rates of transition across retinopathy stages.

RESEARCH DESIGN AND METHODS
The study cohort consisted of 44,871 observed DR events between the calendar years 1990 and 2011 for 4,758 diabetic patients who were diagnosed at 35 years of age or older. The first retinal observation was recorded within a year from diagnosis, and the result was recorded as free of retinopathy. A multistate Markov model was applied for analyzing the development of DR and its relation to the patterns of changes in risk factors.

RESULTS
We observed a consistent risk effect of HbA1c on the progression (no retinopathy to mild background DR [BDR] hazard ratio per SD of HbA1c [HR] 1.42 [95% CI 1.32–1.52], mild BDR to observable BDR HR 1.32 [95% CI 1.08–1.60], and observable BDR to severe nonproliferative/proliferative DR HR 2.23 [95% CI 1.16–4.29]). Similarly, systolic blood pressure (SBP) and diastolic blood pressure increased the risk for the transition from the asymptomatic phase to mild BDR (HR 1.20 [95% CI 1.11–1.30]) and the mild BDR to observable BDR (HR 1.87 [95% CI 1.46–2.40]), respectively. Regression from mild BDR to no DR was associated with lower SBP (HR 0.79 [95% CI 0.64–0.97]) and lower HbA1c (HR 0.76 [95% CI 0.64–0.89]).

CONCLUSIONS
Progression and regression of DR were strongly associated with blood pressure and glycemic exposure.
Anatomical peculiarities of the origin and traject of the superior thyroid artery
Authors: Gavrilidou P. , Iliescu D.M. , R. Baz , Rusali L.M. , Bordei P. 
Published: October 2013

Abstract
the methods of dissection and analysis of angioCT’s. Each of the details was analyzed comparatively on both sides of the body assessing: the origin of the superior thyroid artery in relation to the carotid bifurcation, the face of the external carotid artery that gives origin and the traject of the artery from the origin to the glandular parenchyma. The origin of the superior thyroid artery was evaluated on a number of 64 cases, most frequently having its origin from the external carotid artery, an aspect met 53.125 % of cases, at a distance that was between 1-18 mm. In 28.125 % of cases the superior thyroid artery had its origin in the common carotid trunk at a distance of 1-10 mm caudal to the terminal bifurcation of the common carotid. In 18.75 % of cases, the thyroid artery originated from the carotid bifurcation, which thus ends up by trifurcation. The side of the vessel that emerges the superior thyroid artery was assessed on 42 cases; most commonly the superior thyroid artery having its origin on the medial face, an aspect found in 66.67 % of cases; in 23.81 % of cases originated from the posterior medial and only two cases (4.76 % of cases), both on the left side(8.70 % of cases on the left), the origin of the superior thyroid artery was located on the anterior, respectively faces of the common carotid artery. The traject of the superior thyroid artery was followed on 53 cases, in most cases the artery showing initially a horizontal traject (transverse) towards medially for 1-4 cm, then became obliquely downward, an aspect met in 28.30 % of cases and in 22.64 % of cases, the artery was obliquely downward from its origin. In 11.32 % of cases the traject was obliquely ascending and in 9.43 % of cases the artery was initially obliquely upward for 2-3 cm, after which became transverse. For the remaining 28.30 % of the cases we have met a number of other 5 different patterns of traject but in a small percentage for each of them (5.66% of cases).
Spatial structure of vegetation in a small charophyte dominated lake
Authors: Pukacz Andrzej , Pełechaty Mariusz 
Published: October 2013

Abstract
The aim of the paper was to recognize the current spatial structure and organization of vegetation and the diversity of charophytes on an ecosystem scale of a small, outflow Lake Jasne (Western Poland). The lake is characterized by limited anthropogenic pressure and forested catchment basin. The study was performed in the vegetative season 2010. The vegetation was studied along transect, using the mid-European Braun-Blanquet method of phytosociological relevés. Additionally, basic physical-chemical parameters were measured, to characterize habitat conditions of the lake. The results of physical-chemical analyses evidenced high water quality, and obtained parameter values were typical for mesotrophy. The vegetation survey revealed that almost 70% of the lake’s bottom was overgrown by vegetation. The transects documented the structure of phytolittoral typical for chara-lake and the spatial dominance of charophytes in the studied lake (charophyte meadows reached up to 64% of the phytolittoral area). Charophytes were also defining the maximum depth extent of vegetation in Lake Jasne, reaching 5.6 m. As many as 10 charophyte species were stated: Chara virgata, Ch. aspera, Ch. filiformis, Ch. globularis, Ch. intermedia, Ch. polyacantha, Ch. rudis, Ch. tomentosa, Nitella flexilis and Nitellopsis obtusa, out of which 7 build their own communities. The large number of species (10 of 35 identified so far in Poland) and communities (7 of 30 identified in Poland), as well as their share in phytolittoral, define Lake Jasne as a valuable refuge of European natural habitat, code 3140.
Public Intellectuals and Conscious Pariahs: Hannah Arendt, Edward Said and a Common State in Palestine-Israel
Authors: Piterberg Gabriel 
Published: October 2013

In late nineteenth-century Europe, a distinct, secular socio-political type appeared: the conscious pariah. This essay traces the genealogy of the conscious pariah. Starting from Bernard Lazare and then comparing public intellectuals Hannah Arendt and Edward Said, it argues that the latter, too, can be interpreted as a conscious pariah. Whilst differences are not ignored, the essay highlights the shared political and scholarly insights Arendt and Said offer as conscious pariahs. The renewed relevance of the conscious pariah's politics and scholarship, owing to the project of the common state, runs through the essay both implicitly and explicitly. ‘The Atlantic City Resolution [October 1944] goes even a step further than the Biltmore Program (1942), in which the Jewish minority had granted minority rights to the Arab majority. This time the Arabs were simply not mentioned in the resolution, which obviously leaves them the choice between voluntary emigration and second-class citizenship.’ (Hannah Arendt, ‘Zionism Reconsidered’, Menorah Journal, 33 (October 1944)) Ari Shavit: ‘You sound very Jewish’. Edward Said: 'Of course. I'm the last Jewish intellectual. You don't know anyone else. All your other Jewish intellectuals are now suburban squires. From Amos Oz to all these people here in America. So I'm the last one. The only true follower of Adorno. Let me put it this way: I'm a Jewish-Palestinian. (Edward Said's interview with Ari Shavit, Haaretz, 18 August 2000)
Ceramic veneers with minimum preparation
Authors: da Cunha Leonardo Fernandes , Reis Rachelle , Santana Lino , Romanini Jose Carlos , Carvalho Ricardo Marins , Furuse Adilson Yoshio 
Published: October 2013

ABSTRACTThe aim of this article is to describe the possibility of improving dental esthetics with low-thickness glass ceramics without major tooth preparation for patients with small to moderate anterior dental wear and little discoloration. For this purpose, a carefully defined treatment planning and a good communication between the clinician and the dental technician helped to maximize enamel preservation, and offered a good treatment option. Moreover, besides restoring esthetics, the restorative treatment also improved the function of the anterior guidance. It can be concluded that the conservative use of minimum thickness ceramic laminate veneers may provide satisfactory esthetic outcomes while preserving the dental structure.
Antimicrobial efficiency of photodynamic therapy with different irradiation durations
Authors: Yildirim Cihan , Karaarslan Emine Sirin , Ozsevik Semih , Zer Yasemin , Sari Tugrul , Usumez Aslihan 
Published: October 2013

ABSTRACT
Objective: This study aimed to evaluate the antimicrobial efficiency of PDT and the effect of different irradiation durations on the antimicrobial efficiency of PDT. Materials and Methods: Sixty freshly extracted human teeth with a single root were decoronated and distributed into five groups. The control group received no treatment. Group 1 was treated with a 5% sodium hypochlorite (NaOCl) solution. Groups 2, 3, and 4 were treated with methylene-blue photosensitizer and 660-nm diode laser irradiation for 1, 2, and 4 min, respectively. The root canals were instrumented and irrigated with NaOCl, ethylenediamine-tetraacetic acid, and a saline solution, followed by autoclaving. All the roots were inoculated with an Enterococcus faecalis suspension and brain heart infusion broth and stored for 21 days to allow biofilm formation. Microbiological data on microorganism load were collected before and after the disinfection procedures and analyzed with the Wilcoxon ranged test, the Kruskal-Wallis test, and the Dunn′s test. Results: The microorganism load in the control group increased. The lowest reduction in the microorganism load was observed in the 1-min irradiation group (Group 2 = 99.8%), which was very close to the results of the other experimental groups (99.9%). There were no significant differences among the groups. Conclusions: PDT is as effective as conventional 5% NaOCl irrigation with regard to antimicrobial efficiency against Enterococcus faecalis.
Influencia de la simetría facial en la elección de pareja
Authors: Portales Rosas Katherine , Gil Burmann Carlos , Beltrami Boisset Marcial 
Published: October 2013

Muchos estudios sugieren que la simetría facial, como indicador de estabilidad en el desarrollo y de la salud del individuo, influye en la evaluación de las características de la pareja. Para determinar la importancia de la simetría facial en la elección de pareja, aplicamos, en diversos espacios públicos de Santiago de Chile, una encuesta a 718 personas heterosexuales: 456 mujeres y 262 hombres. Ellos evaluaron tres imágenes de rostros de personas del sexo opuesto con diferentes niveles de simetría facial. Concluimos que la simetría facial influye en la evaluación de las características de una pareja pero, en adición a la simetría, otros factores como el uso de productos de belleza pueden ser señales fenotípicas más importantes que la simetría facial.
Masculinidad y hombre maltratador ¿pueden las creencias de hombres y mujeres propiciar violencia de género?
Authors: Duarte Efraín , Gómez Jorge Francisco , Carrillo Carlos David 
Published: October 2013

Esta investigación tuvo como propósito explorar la relación entre las creencias sobre masculinidad y hombre maltratador, incorporando la perspectiva de género como una herramienta para el análisis de dichas creencias, y tomando en cuenta la opinión de mujeres y de hombres con respecto a ellas. El estudio se llevó a cabo en el Estado de Yucatán, México. Participaron 117 mujeres (58.5%) y 83 hombres (41.5%). De ellos, 173 (86.5%) tenían residencia en la zona urbana y 27 (13.5%) residían en la zona rural. La recolección de datos se realizó a través de dos escalas: la Escala de Creencias acerca de la Masculinidad (ECAM), (Gómez & Carrillo, 2007) y la Escala de Creencias acerca del Hombre Maltratador (ECHOM), (Gómez, Carrillo & Revilla, 2008). Todo esto, dentro del contexto de un estudio cuasiexperimental, ex post facto, transversal, de campo, de dos muestras independientes. Los resultados muestran que existen diferencias en las creencias acerca de la masculinidad y el hombre maltratador, entre las mujeres y los hombres participantes; que las creencias sobre estos dos constructos se relacionan significativamente, encontrando -en las mujeres- mayor relación con el uso de la violencia como consecuencia del discurso y normativa social que se "impone" a los hombres; y, por otro lado, que tanto mujeres como hombres consideran que la violencia es normal que la ejerzan los hombres, aunque ambos la rechazan. Por último, es importante señalar que el constructo de masculinidad está basado en la concepción hegemónica del término, por lo tanto, sería interesante explorar los modelos alternativos de la masculinidad.
Valoración de las competencias de Psicología: Estudio exploratorio en muestras de estudiantes y profesionales activos
Authors: Suárez Ximena Alejandra 
Published: October 2013

Por medio de un cuestionario se caracterizan y comparan las percepciones de importancia y autovaloración en ocho competencias asociadas a la profesión de psicólogo, de 58 psicólogos activos de la Región de la Araucanía (Chile) y 46 estudiantes de los últimos cursos de la carrera de psicología de una Universidad Estatal de la misma región. Los resultados indican una mayor valoración para las competencias de diagnóstico y de intervención psicológica individual en ambos grupos; la existencia de diferencias significativas a favor del grupo de profesionales en la importancia asignada a las competencias evaluadas; y una autovaloración en los estudiantes significativamente menor al nivel de importancia que le asignan a las competencias en estudio.
Servicio en beneficio de la comunidad: una aproximación cuantitativa a la justicia juvenil restaurativa en Chile
Authors: Díaz Bórquez Daniela Aída 
Published: October 2013

Este estudio observó 67 casos de jóvenes egresados del Programa Servicio en Beneficio de la Comunidad (SBC) para identificar prácticas efectivas en materia de intervención. Mediante una regresión logística fue posible predecir el éxito del SBC en función de las características de la intervención desarrollada por los profesionales.Los jóvenes que prestan servicios de alta base comunitaria (actividades recreativas/voluntariado) presentarían cinco veces más chances de lograr los objetivos de intervención, respecto de quienes prestan servicios de escaso vínculo comunitario, tales como labores administrativas o restauración de infraestructura pública. Los resultados generan evidencia empírica a favor del potencial restaurativo del SBC cuando permite restituir el vínculo entre el joven y la comunidad, simbólicamente destruido en la comisión del delito.
Constructividad y Razón narrativa: bases para un operar en terapia narrativa
Authors: Zlachevsky Ojeda Ana María 
Published: October 2013

El presente artículo muestra cómo el concepto de “narrativa” y el de constructivismo o constructividad han llevado a equívocos. Ello se liga con las dos tradiciones que han coexistido en el pensamiento psicológico. La cientificista, por un lado, y la fenomenología hermenéutica, por otro, teniendo cada postura una diferente manera de entender “lo humano”; por tanto, de comprender lo narrativo. La constructividad como postura epistemológica se liga al pensamiento de Maturana y Varela, acentuando las características del observador que está a la base de esta comprensión. Se termina el artículo proponiendo la razón narrativa, versus la razón lógica, como proceso que permitiría entender lo narrativo en la postura fenomenológica hermenéutica.