bluuebunny/crossref_metadata_2025_split huggingface dataset:
Integrating the thematic approach into information literacy courses
Authors: Price Elizabeth , Richardson Rebecca 
Published: February 2015

Purpose– The purpose of this paper is to review selected publications in library-related literature and discuss the thematic approach to course design in colleges and universities and how it has been implemented into information literacy (IL) courses.Design/methodology/approach– A literature review of peer-reviewed journals, professional journals, magazines and blogs contextualizes the thematic approach to instruction at the college and university levels. Search terms included “thematic approach”, “thematic approach in education” and “theme-based instruction”; the search was restricted to articles published in the past 20 years.Findings– In addition to the IL courses, thematic-based instruction has been used in biology, chemistry, English, French literature, history, mathematics, philosophy and sociology courses in college and university campuses. While instructors report that the thematic approach enhances student learning, few studies have directly tested the impact. No studies have been published within the library science literature.Originality/value– Thematic approach is a newer concept in the world of IL instruction. While many professional journal articles and blog posts provide in-depth case studies of how thematic-based instruction has been implemented, this article draws from all disciplines and features a succinct summary of what works, what does not work and how to best implement a thematic approach in an IL course.
Occupational therapy inpatient rehabilitation interventions with deconditioned older adults following an acute hospital admission: A Delphi study
Authors: Timmer Amanda J. , Unsworth Carolyn A. , Taylor Nicholas F. 
Published: February 2015

Background/aimOlder adults admitted to an acute hospital setting with an illness often experience deconditioning. Although occupational therapists frequently work with deconditioned older adults in inpatient rehabilitation programmes, limited information exists regarding the type of interventions used and how these interventions are provided. This study aimed to determine the level of consensus among Australian occupational therapists about occupational therapy service delivery and interventions commonly used during inpatient rehabilitation with older adults who have become deconditioned during acute hospital admission for a medical illness.MethodsThe Delphi technique was used to reach consensus among expert occupational therapists regarding service delivery and interventions commonly used in an ideal clinical setting. Data were analysed from three rounds of surveys and the percentage of agreement between clinicians were calculated.ResultsTwenty‐six participants completed round one survey, with 24 completing subsequent surveys (92% response rate). Fifteen commonly used interventions were identified, including showering/dressing, light meal preparation and home assessment. Consensus was reached on commonly used aspects of service delivery, including intervention provision, programme length, team members and follow up after discharge.ConclusionResults generated may assist in guiding occupational therapists in the attributes of service delivery and the type of interventions currently considered best practice when working with deconditioned older adults in a rehabilitation setting. The information provides preliminary data for effectiveness studies.
Are health promotion and prevention interventions integrated into occupational therapy practice with older adults having disabilities? Insights from six community health settings in Québec, Canada
Authors: Turcotte Pier‐Luc , Carrier Annie , Desrosiers Johanne , Levasseur Mélanie 
Published: February 2015

Background/aimIncreasingly, health‐care systems should promote seniors’ health and prevent disability. As they enable engagement in meaningful activities within the individuals’ living environment, community occupational therapists have great potential to contribute to health promotion and prevention. Despite this potential, little is known about current health promotion and prevention activities in occupational therapy community practice. This study thus aimed to: (1) identify health promotion and prevention interventions used with seniors having disabilities, and (2) explore barriers to integrating such interventions into practice.MethodsSecondary data analysis of a qualitative study was carried out using thematic saliency analysis. Eleven community occupational therapists working with seniors having disabilities were recruited in six community health settings in Québec, Canada. Observations of 12 home visits, followed by 12 semi‐structured interviews, were conducted with occupational therapists.ResultsMost interventions involved optimising independence in personal care and mobility. Explicit health promotion interventions were limited and included enabling healthy lifestyles by increasing health literacy and empowerment. Meaningful activities (leisure, community participation) were not targeted. Barriers to integrating health promotion into practice were clients’ complex health conditions and limited openness to change combined with organisational and professional obstacles, such as a misunderstanding of occupational therapists’ role in health promotion.ConclusionsHealth promotion and prevention interventions are not intentionally integrated into community occupational therapy practice with seniors having disabilities. As a result, seniors’ needs to engage in meaningful activities might remain unmet. Overcoming barriers to integrating health promotion and prevention in practice could help improve population health and wellbeing.
Wound edge protector for prevention of surgical site infection in laparotomy: an updated systematic review and meta‐analysis
Authors: Zhang Ming‐Xia , Sun Yi‐Hui , Xu Zheng , Zhou Ping , Wang Hong‐Xia , Wu Yong‐You 
Published: February 2015

AbstractBackgroundAn updated meta‐analysis based on randomized controlled trials (RCTs) was conducted to evaluate the efficacy of wound edge protector (WEP) in the prevention of surgical site infection (SSI) in patients undergoing laparotomies.MethodsMeta‐analysis was conducted using Review Manager 5.2. The pooled risk ratio was estimated with random‐effect model. Medline, Embase, the Cochrane library, reference lists and conference proceedings were data sources. Two independent reviewers screened studies for inclusion and data extraction. Eligible trials were RCTs enrolling patients accepting laparotomies to assess the effectiveness of WEP.ResultsEleven RCTs totalling 2344 patients met the inclusion criteria. Six trials (1589 patients) testing the single‐ring design WEP did not show a statistically significant reduction in SSI of laparotomy (RR 0.76, 95% CI 0.51–1.12). Pooled analysis of the five trials (755 patients) that tested the effect of dual‐ring design WEP on SSI showed a significant reduction (RR 0.29, 95% CI 0.15–0.55). The combined data of the 11 trials favoured the effect of WEP (RR 0.58, 95% CI 0.39–0.87). Analysis adjusted by the degrees of contamination revealed that WEP is effective in reducing the incidence of SSI after laparotomy of contamination incision (RR 0.43, 0.26–0.72) but failed to demonstrate such effect in clean/contaminated and dirty incisions (RR 0.72, 95% CI 0.43–1.21; RR 0.82, 95% CI 0.43–1.55, respectively).ConclusionsOur exploratory meta‐analysis suggests that WEP reduces the incidence of SSI in patients receiving laparotomies, especially in the circumstance of dual‐ring WEP and in contaminated incisions. In order to fully assess the effectiveness of WEP, large‐scale and well‐designed RCTs are still needed in the future.
Early insights into neuromyelitis optica recounted by a past member of the Executive Committee of the Japanese Society for Neuroimmunology
Authors: Ohara Yoshiro 
Published: February 2015

AbstractI started my career as a clinical neurologist at the Institute of Brain Diseases, Tohoku University School of Medicine in 1975. Since then, I have been closely associated with the Neuroimmunological Research Committee of the Ministry of Health, Labor and Welfare, and the Japanese Society for Neuroimmunology. In this commentary, I will summarize an untold story regarding multiple sclerosis and neuromyelitis optica in Japan.
Can Internet Search Queries Help to Predict Stock Market Volatility?
Authors: Dimpfl Thomas , Jank Stephan 
Published: February 2015

AbstractWe study the dynamics of stock market volatility and retail investors' attention to the stock market. The latter is measured by internet search queries related to the leading stock market index. We find a strong co‐movement of the Dow Jones' realised volatility and the volume of search queries for its name. Furthermore, search queries Granger‐cause volatility: a heightened number of searches today is followed by an increase in volatility tomorrow. Including search queries in autoregressive models of realised volatility improves volatility forecasts in‐sample, out‐of‐sample, for different forecasting horizons, and in particular in high‐volatility phases.
S100A7 acts as a dual regulator in promoting proliferation and suppressing squamous differentiation through GATA‐3/caspase‐14 pathway in A431 cells
Authors: Li Ting , Qi Zhi , Kong Fei , Li Yunguang , Wang Rui , Zhang Weiqing , Shang Yu , Huang Lingyun , He Dacheng , Xiao Xueyuan 
Published: February 2015

AbstractS100A7 is expressed in many squamous cell carcinomas (SCCs), such as SCC of the skin, and well‐differentiated SCC always displays stronger staining of this protein. A431 cells, an epidermal cancer cell line, were selected as a cell model to investigate the roles and mechanism of S100A7 in SCC of the skin. In this study, we demonstrated that the overexpression of S100A7 in A431 cells significantly promoted cell proliferation in vitro and tumor growth in vivo, whereas it suppressed the expression of GATA‐3, caspase‐14 and three squamous differentiation markers, keratin‐1, TG‐1 and involucrin. Conversely, the overexpression of caspase‐14 not only significantly decreased cell proliferation and delayed tumor growth but also markedly induced the expression of three squamous differentiation markers, whereas S100A7 and GATA‐3 were not influenced. Further evidence showed that silencing GATA‐3 greatly inhibited the expression of caspase‐14 and three differentiation markers, while the expression of S100A7 was not changed; contrary results were obtained when overexpressing GATA‐3. Importantly, restoring the expression of GATA‐3 and caspase‐14 in A431‐S100A7 cells could bypass the ability of S100A7 to increase cell viability and repress squamous differentiation. These data suggested that S100A7 expression in SCC may play an important role in the maintenance of SCC cell dedifferentiation, at least in SCC of the skin.
Impaired T‐cell‐dependent protection against Leishmania major infection in HIV‐positive patients is associated with worsened disease outcome
Authors: Ngouateu Omer Bébé , Weller Karsten , Bröhl Konrad , Kamtchouing Pierre , Same‐Ekobo Albert , Dondji Blaise , Maurer Marcus , von Stebut Esther 
Published: February 2015

AbstractCutaneous leishmaniasis (CL) patients coinfected with HIV are known to show a more severe, prolonged course of disease; the immunological basis is not known. We now assessed clinical features, sera and skin biopsies of HIV+ and HIV− patients with CL to identify drivers of increased susceptibility to Leishmania. CL lesion numbers, surface, and healing duration were significantly increased in HIV+ as compared to HIV− patients (2.5, 14 and >4‐fold, respectively). Patients with HIV infection exhibited lower serum Leishmania‐specific IgG levels and decreased IL‐6 and IL‐8. Most importantly, dramatically decreased numbers of CD4+ T cells (approximately eightfold), but not CD8+ cells, together with fewer CXCR3+ Th1 cells, fewer Foxp3+ effector/regulatory T cells, and reduced levels of IFN‐γ expression were found in lesional skin. Our findings suggest that compromised CD4+ T‐cell responses may be responsible for worsened disease outcome leading to defects in parasite elimination in the absence of sufficient numbers of IFN‐γ‐producing Th1 cells.
Real‐life evidence in evaluating effectiveness of treatment in Haemophilia A with a recombinant FVIII concentrate: A non‐interventional study in emerging countries
Authors: Gouider E. , Rauchensteiner S. , Andreeva T. , Al Zoebie A. , Mehadzic S. , Nefyodova L. , Brunn M. , Tueckmantel C. , Meddeb B. 
Published: February 2015

SummarySome progress has been made regarding availability of recombinant factor VIII concentrates and prophylaxis for haemophilia A in emerging countries, where plasma‐derived concentrates were used in the vast majority. Clinical studies to document their introduction and effectiveness are so far not widely available in literature. This non‐interventional study evaluates the real‐life effectiveness and safety of prophylactic and on‐demand treatment with recombinant factor VIII formulated with sucrose (rFVIII‐FS) for bleed control and preservation of joints in emerging countries from Eastern Europe, North Africa and Middle East area. One hundred and eighty‐six patients from 11 countries were enrolled, mean ± SD age 12.8 ± 12.7 years. At enrolment, majority (79.6%) had severe haemophilia A (<2% IU mL−1), 47.8% had a target joint, 15% had an inhibitor history and one patient was on immune tolerance induction. During the 24‐month observation period, 58.1% of the patients were prescribed prophylaxis at every visit, 31.7% were on an on‐demand regimen. Patients with severe haemophilia A on prophylaxis (n = 82) had a mean annual rate of treated bleeds of 2.8 ± 4.4, whereas it was 19.1 ± 32.0 for the on‐demand group (n = 31), and a mean total Gilbert Score of 9.9 ± 10.3 at baseline and 4.1 ± 6.7 at study end; vs. 15.2 ± 17.3 and 13.7 ± 17.1 for on‐demand respectively. The majority of the bleeds (91.1%) were treated with one or two infusions. Four patients without inhibitor history had a first positive inhibitor test during the study. This study demonstrates the effective use of rFVIII‐FS in emerging countries and adds to the established safety profile of rFVIII‐FS.
How fit are children and adolescents with haemophilia in Germany? Results of a prospective study assessing the sport‐specific motor performance by means of modern test procedures of sports science
Authors: Seuser A. , Boehm P. , Ochs S. , Trunz‐Carlisi E. , Halimeh S. , Klamroth R. 
Published: February 2015

SummaryThere are a lot of publications on the physical fitness of patients with haemophilia (PWH), however, most studies only reflect individual sport‐specific motor capacities or focus on a single fitness ability. They involve small patient populations. In this respect principal objective of this study was to compare the physical fitness in all respects and the body composition of young PWH to healthy peers based on the most valid data we could get. Twenty‐one German haemophilia treatment centres were visited from 2002 to 2009. PWH between 8 and 25 years were included. They performed a five‐stage fitness test covering the sport‐specific motor capacities for coordination, measured by one leg stand, strength, aerobic fitness and mobility as well as body composition. The patients' results were compared with age‐ and gender‐specific reference values of healthy subjects. Two hundred and eighty‐five PWH (mean age 13.2 ± 4.5 years, 164 PWH with severe disease) were included prospectively in the study. PWH are significantly below the reference values of healthy subjects in the one‐leg stand test, the mobility of the lower extremity, the strength ratio of chest and back muscles and the endurance test. In body composition, the back strength and the mobility of the upper extremity PWH are significantly above the reference values. There are no significant differences in abdominal strength. In conclusion we found specific differences in different fitness abilities between PWH and healthy subjects. Knowing this, we are able to work out exercise programmes to compensate the diminished fitness abilities for our PWH.
The effects of single hemodialysis session on arterial stiffness in hemodialysis patients
Authors: Öğünç Handan , Akdam Hakan , Alp Alper , Gencer Fatih , Akar Harun , Yeniçerioğlu Yavuz 
Published: February 2015

AbstractIncreased arterial stiffness in hemodialysis patients is a strong predictor of cardiovascular morbidity and mortality. Pulse wave velocity (PWV) and augmentation index (AIx), which are markers of arterial stiffness, were used to determine the severity of vascular damage noninvasively. This study aimed to investigate the effects of solute volume removal and hemodynamic changes on PWV and AIx of a single hemodialysis session. Thirty hemodialysis patients were enrolled in the study. Before initiation of hemodialysis, every 15 minutes during hemodialysis, and 30 minutes after the completion of the session, measurements of PWV and AIx@75 (normalized with heart rate 75 bpm) were obtained from each patient. Body composition was analyzed by bioimpedance spectroscopy device before and 30 minutes after completion of the hemodialysis session. During the hemodialysis, no significant change was observed in AIx@75. However, PWV decreased steadily during the session reaching statistically significant level at 135th minute (P = 0.026), with a maximal drop at 210th minute (P < 0.001). At 210th minute, decrease in PWV correlated positively with the decrease in central systolic blood pressure, central diastolic blood pressure, central pulse pressure, augmentation pressure, and AIx@75. Multiple regression analysis showed that decrease in PWV at 210th minute was associated with decrease in central systolic blood pressure and central pulse pressure. Ultrafiltration during hemodialysis had no significant effect on PWV and AIx@75. Delta urea correlated positively with delta PWV at 240th minute. A significant decrease in PWV was observed during hemodialysis and correlated with urea reduction; however, we were unable to document any effect of volume removal on arterial stiffness.
PHILOSOPHY OF HISTORY'S RETURN
Authors: Harootunian Harry 
Published: February 2015

ABSTRACTKojin Karatani's Structure of World History seeks to rescue the philosophy of history and restore to it the relationship between philosophical reflection and historical practice. This connection is particularly pertinent in Karatani's case since he had earlier worked out the philosophical scaffolding of this monumental study in his book Transcritique: On Kant and Marx, which embarked on a “return to Capital once more to read the potential that has been overlooked.” By juxtaposing Marx to Kant and vice versa to discover the importance of exchange over production, he found what was to become the informing principle of his later philosophy of history. While Karatani's accounting of the structure of world history presumes to recount the passage of the world's history from nomadic societies to the present as a condition to rethink “social formations” from a perspective that recalls the form of a stagist philosophy of history attributed to Marx and Engels, he has abandoned its informing principle of the modes of production. Instead, he offers the perspective of modes of exchange, which means waiving any consideration concerning who owns the means of production: the putative “economic base” underlying superstructural representations like the state, religion, and culture upheld by a vulgate tradition of Marxian historical writing and discounted by bourgeois historiography as deterministic. The decision to shift to modes of exchange means rooting the primary mode of exchange taking place first in nomadic societies, rather than forms of production and archaic communal ownership of land. Although his revised scheme still accords priority to the economic, the putative division between base and superstructures still persists, even though the latter are still produced by the former, which is now the mode of exchange. Whereas Marx privileged commodity exchange as dominant, Karatani places greater emphasis on the earliest mode of exchange, which consists of the “pure gift,” associated with early nomadic social formations and reciprocity practices by clans, and seems to offer nomadic/clan communalism as a model that resembles Marx's own strategic linking of the surviving Russian commune and contemporary capitalism. The point to this project is to transcend the hegemonic trinity of capital, nation, and state and satisfy a desire to share with other globalists a vision that aims to overcome the defects of capitalism and the nation‐state and the failure of a Marxian expectation that nation‐states will simply wither away with the final surpassing of capitalism. To this end, Karatani's appeal to Kant offers to inject a moral element absent in the merely economic structure of history that will thus provide the promise of “world peace,” which ultimately requires an abolition of the nation‐state as a condition for realizing a “simultaneous bourgeois revolution” that would finally overcome state and capital and establish a world federation.
Optimal habitat conditions for the globally threatened Aquatic Warbler Acrocephalus paludicola in eastern Poland and their implications for fen management
Authors: Kloskowski Janusz , Tanneberger Franziska , Marczakiewicz Piotr , Wiśniewska Anna , Choynowska Agata 
Published: February 2015

To identify optimal habitat for the Aquatic Warbler Acrocephalus paludicola, a flagship species of fen mires, we related numbers of singing males to habitat variables in all core breeding sites in eastern Poland. The density of male Aquatic Warblers increased with increasing ground cover by water and mosses and litter layer height, and was highest where vegetation was 60–90 cm tall. Male densities also increased with the biomass of arthropods > 10 mm length, estimated by sweep netting, and with the abundance of spiders, estimated by pan trapping. We suggest that habitat management should take into account species‐specific morphological adaptations, nest safety and arthropod productivity. Prevention of vegetation succession is a conservation priority for open fen mires. However, modern management practices to achieve this, especially mowing using tracked vehicles, should be evaluated and optimized to ensure that such practices do not adversely affect the long‐term development of moss cover and litter structure.
Arguments for and against financial literacy education: where to go from here?
Authors: Alsemgeest Liezel 
Published: February 2015

AbstractCurrently, everyone is brandishing financial literacy education as the answer to the global personal financial crisis. However, there are a few advocates against financial literacy education. There is contention whether financial literacy education actually leads to effective financial behaviours. The purpose of this theoretical article is to state the various arguments for and against financial literacy education and suggest possible guidelines for interventions by governments and institutions in an effort to increase financial well‐being. There are no easy answers to this complex problem and financial illiteracy should not be presented as the sole culprit. Basic financial literacy education is needed to manage day‐to‐day finances; however, specialist areas such as investments and retirement planning should be left to professionals. It is suggested that financial literacy education should focus not only on cognitive factors but also on non‐cognitive and affective factors that might override rational decision making.