bluuebunny/crossref_metadata_2025_split huggingface dataset:
To Cause Harm and to be Harmed by Others: New Perspectives on Alcohol's Harms to Others
Authors: Seid Abdu K. , Grittner Ulrike , Greenfield Thomas K. , Bloomfield Kim 
Published: October 2015

Objective To examine how sociodemographic factors and alcohol consumption are related to a four-way typology of causing harm to others and/or being harmed by othersș and one's own drinking. Data and Methods Data from the 2011 Danish national survey ( n = 2,569) were analyzed with multinomial logistic regression. Results Younger age and heavy drinking were significant correlates of both causing harm and being harmed. Women and better educated respondents were more likely to report negative effects on relationship and family from another's drinking. Better educated respondents had higher risks for work, financial, or injury harms from another's drinking. Mean alcohol consumption and risky single occasion drinking were related to both causing harm and being harmed from one's own drinking. Conclusions Drinking variables were the strongest correlates of causing harm and being harmed. Efforts to reduce risky drinking may also help reduce exposures to collateral harm.
De prijs voor transparantie en publicatie
Authors: Brouwer O.W. 
Published: October 2015

De prijs voor transparantie en publicatie
Toegang tot processtukken met standpunten die de Europese instellingen en Lidstaten innemen in procedures bij de EU-rechter ondervindt toenemende belangstelling.Dit is de tweede zaak waarin de grenzen worden verkend van toegang tot processtukken via de Eurowob.Breyer is deels succesvol in zijn verzoek tot toegang maar wordt in de proceskostenveroordeling gestraft voor het plaatsen van kritische kanttekeningen en processtukken van zijn Eurowobzaak op zijn website. De vraag is of dit rechtens juist is. De Commissie heeft hogere voorziening ingesteld tegen het hier besproken arrest.Gerecht 27 februari 2015, zaak T-188/12, Patrick Breyer (gesteund door interveniënten Republiek Finland, Koninkrijk Zweden)/Europese Commissie, ECLI:EU:T:2015:124. Hogere voorziening verzocht in C-213/15 P.
The Effects of Motivation and Satisfaction on Destination Loyalty at the Thailand -Laos (PDR) Border
Authors: Chindaprasert Kantimarn , Yasothornsrikul Paradee , Esichaikul Ranee 
Published: October 2015

AbstractOver the past few decades, the influence of the Greater Mekong Sub-region (GMS) program and Asian Economic Community (AEC) framework of ASEAN has led to an increasing number of tourists visiting Thailand and Laos (PDR) border sites. Accordingly, the Thailand-Laos (PDR) border destination appears to have a high tourism market potential as it is seen as an important tourist attraction, nationally and internationally. The investigation of cross-border tourism in this area will benefit the development of the tourism industry along Thailand and Laos (PDR). Consequently, the current study aims to investigate a structural model explaining destination loyalty and its inter-relationship with push and pull motivation, and satisfaction, in the context of Thai revisits to the Thailand-Laos (PDR) border destination. A total of 400 questionnaires were collected and analysed by a Structural Equation Modeling software called Mplus version 6.12. Findings of this study reveal that push motivation and satisfaction are both determinants of Thai visitors’ destination loyalty for the Thailand-Laos border. Implications for Thailand and Laos (PDR) border destination managers are also discussed.
Fluid circulation and carbonate vein precipitation in the footwall of an oceanic core complex, Ocean Drilling Program Site 175, Mid‐Atlantic Ridge
Authors: Schroeder Tim , Bach Wolfgang , Jöns Niels , Jöns Svenja , Monien Patrick , Klügel Andreas 
Published: October 2015

AbstractCarbonate veins recovered from the mafic/ultramafic footwall of an oceanic detachment fault on the Mid‐Atlantic Ridge record multiple episodes of fluid movement through the detachment and secondary faults. High‐temperature (∼75–175°C) calcite veins with elevated REE contents and strong positive Eu‐anomalies record the mixing of up‐welling hydrothermal fluids with infiltrating seawater. Carbonate precipitation is most prominent in olivine‐rich troctolite, which also display a much higher degree of greenschist and sub‐greenschist alteration relative to gabbro and diabase. Low‐temperature calcite and aragonite veins likely precipitated from oxidizing seawater that infiltrated the detachment fault and/or within secondary faults late or post footwall denudation. Oxygen and carbon isotopes lie on a mixing line between seawater and Logatchev‐like hydrothermal fluids, but precipitation temperatures are cooler than would be expected for isenthalpic mixing, suggesting conductive cooling during upward flow. There is no depth dependence of vein precipitation temperature, indicating effective cooling of the footwall via seawater infiltration through fault zones. One sample contains textural evidence of low‐temperature, seawater‐signature veins being cut by high‐temperature, hydrothermal‐signature veins. This indicates temporal variability in the fluid mixing, possibly caused by deformation‐induced porosity changes or dike intrusion. The strong correlation between carbonate precipitation and olivine‐rich troctolites suggests that the presence of unaltered olivine is a key requirement for carbonate precipitation from seawater and hydrothermal fluids. Our results also suggest that calcite‐talc alteration of troctolites may be a more efficient CO2 trap than serpentinized peridotite.
Predictions for impactor contamination on Ceres based on hypervelocity impact experiments
Authors: Daly R. Terik , Schultz Peter H. 
Published: October 2015

AbstractNew experiments predict that Ceres should be extensively contaminated with meteoritic debris derived from the asteroid belt. All types of impactors likely contribute to the contamination. Ceres may accrete debris more efficiently if it is ice‐rich because of enhanced projectile survival and retention in porous ice targets. Experiments indicate that if a silicate regolith lag protects subsurface ice, then some of the projectile should be injected into the regolith during high‐angle impacts, thereby hiding part of the projectile component from view. If impacts excavate ice, sublimation will gradually concentrate projectile relics into a surficial lag. In contrast, if the near‐surface lacks ice, then accreted meteoritic debris should be distributed throughout a vertically mixed regolith. High‐resolution images may reveal pristine projectile relics lining some crater floors. Moreover, we predict that the surface of Ceres is not exclusively endogenic and may be dominated by delivered exogenic debris.
ENSO and meridional modes: A null hypothesis for Pacific climate variability
Authors: Di Lorenzo E. , Liguori G. , Schneider N. , Furtado J. C. , Anderson B. T. , Alexander M. A. 
Published: October 2015

AbstractPacific low‐frequency variability (timescale > 8 years) exhibits a well‐known El Niño‐like pattern of basin‐scale sea surface temperature, which is found in all the major modes of Pacific decadal climate. Using a set of climate model experiments and observations, we decompose the mechanisms contributing to the growth, peak, and decay of the Pacific low‐frequency spatial variance. We find that the El Niño‐like interdecadal pattern is established through the combined actions of Pacific meridional modes (MM) and the El Niño–Southern Oscillation (ENSO). Specifically, in the growth phase of the pattern, subtropical stochastic excitation of the MM energizes the tropical low‐frequency variance acting as a red noise process. Once in the tropics, this low‐frequency variance is amplified by ocean‐atmospheric feedbacks as the pattern reaches its peak phase. At the same time, atmospheric teleconnections distribute the variance from the tropics to the extratropics, where the pattern ultimately decays. In this stochastic red noise model of Pacific climate, the timescale of the extra‐tropical/tropical interactions (1–2 years) permits the stochastic excitation of the ENSO‐like pattern of decadal and interdecadal variance.
Investigating the Relative Contributions of Computerised Working Memory Training and English Language Teaching to Cognitive and Foreign Language Development
Authors: Hayashi Yuko , Kobayashi Taisei , Toyoshige Tsuyoshi 
Published: October 2015

SummaryThe current study reports on an intervention study that investigated the relative contributions of 5‐week English language training (ELT) and 5‐week working memory training (WMT) to improvements in English language knowledge and working memory capacity in university learners of English as a foreign language. The participants were allocated to one of the following three experimental groups and a control group: (i) ELT only; (ii) WMT only; and (iii) both WMT and ELT. The results showed that intervention effects were pronounced in the WMT + ELT group, who improved scores on the reading span test and all tests of verbal and visuo‐spatial short‐term and working memory. The gains on verbal short‐term (Japanese) and working memory (Japanese and English) were maintained 3 months later. None of the interventions, single or combined, were associated with gains in foreign language knowledge, however. The sustained effects of the dual approach and its implications are discussed. Copyright © 2015 John Wiley & Sons, Ltd.
An Imperfect Match? Crime‐related Context Influences Fingerprint Decisions
Authors: Osborne Nikola K. P. , Zajac Rachel 
Published: October 2015

SummaryResearch suggests that fingerprint interpretation is vulnerable to contextual influence. Specifically, as contextual information increases in emotional intensity, people appear to increase the rate at which they deem fingerprint pairs to share the same source. We investigated three alternative explanations for this finding: (i) that participants who complete multitrial experiments might make more matches over time; (ii) that the provision of any additional information could influence decision‐making; and (iii) that the effect could be limited to dichotomous response options. In Experiment 1, participants forced to make a match or non‐match decision on 96 fingerprint pairs made more matches when pairs were preceded by crime‐related photographs, relative to neutral photographs or no photographs. In Experiment 2, where an ‘unsure’ option was available, crime‐related context did not influence matches but decreased non‐matches. Further research is necessary to determine the relative contributions of emotionality and motivation to these effects. Copyright © 2015 John Wiley & Sons, Ltd.
Looking and Drawing
Authors: Cook Peter 
Published: October 2015

AbstractPeter Cook is the doyen of the architectural drawing world. He enthuses and champions the graphic in architectural schools across the globe, while producing extraordinary images within his own London‐based practice. Here he offers us the rare chance to look over his shoulder at CRAB studio, proffering some rare tips and insights; he shares his graphic predilections and recounts the evolution of some of his most recent drawings.
Plug‐In, Clip‐On, Tune‐Up: A Throwaway Architecture with Optional Extras
Authors: Herron Simon 
Published: October 2015

AbstractFor Simon Herron drawing is an innate, even an addictive, compulsion. Here he lets us into his own personal world of drawing: ‘a private haptic language of invention’, which simultaneously has the power to shock and resonate with its time. He traces his graphic lineage back to the work of his father, Ron Herron of Archigram, and projects it forwards through the output of his students.
All Night Long: The Architectural Jazz of the Texas Rangers
Authors: Morris Mark 
Published: October 2015

AbstractIn the mid‐1950s, a group of young faculty at the University of Texas School of Architecture in Austin ‐ aka the Texas Rangers ‐ entertained themselves with weekly sessions of a sophisticated, collective drawing game, ‘Dot‐the‐Dot’, in which there was an emphasis on inventive fluency in hand drawing as well as an innate knowledge of historic European city plans. What happened when Mark Morris, Visiting Associate Professor at Cornell University, decided in a design studio to ask present‐day students to revive the game?
Two Sides of the Page: The Antifact and the Artefact
Authors: Cantley Bryan 
Published: October 2015

AbstractFor Bryan Cantley technology has introduced new possibilities for drawing with ‘the ability to render conditions of transformation, phase shifting, entropy and revolution’. It has also prompted a rethink of the phenomenological relationship of architectural drawing with the world; between the page and objects; between the antifact and the artefact. He makes an analogy between the legal status of the unborn child and nascent, unbuilt drawn architecture.
Rhodium(I)‐Catalyzed [2+2+2] Cycloaddition between Allene, Alkyne, and Imine via a Strained Azarhodacycle Intermediate
Authors: Oonishi Yoshihiro , Hato Yoshio , Sato Yoshihiro 
Published: October 2015

AbstractThe rhodium(I)‐catalyzed intramolecular [2+2+2] cycloaddition between allenes, alkynes, and imines has been developed. This cyclization proceeds via a strained azarhodacycle, giving a 5,7‐fused cyclic amide or a tricyclic product containing an 8‐azabicyclo[3.2.1]octane skeleton in high yield.magnified image
The allocation and interaction model: A new model for predicting total energy expenditure of highly active humans in natural environments
Authors: Ocobock Cara 
Published: October 2015

ObjectiveThe purpose of this study was to develop a new model, the Allocation and Interaction Model (AIM), to better predict human total energy expenditure (TEE) among a group of highly active humans living in a variety of natural environments. AIM estimates were tested to determine if it produces more accurate TEE predictions than the Factorial Method.MethodsAIM includes metabolic cost terms for basal metabolic rate, thermoregulation, and the thermic effect of food, as well as more accurate activity cost estimations. AIM was tested using doubly labeled water and Flex‐Heart Rate (Flex‐HR)‐measured TEEs of healthy, highly active adults (N = 59) participating in National Outdoor Leadership School semester‐long courses. Data from a month‐long pilot study (N = 6) were also included.ResultsAIM produced TEE estimates that were not significantly different from measured energy expenditure values. Overall, AIM came within 4.1% of measured values; the Factorial Method underestimated by over 25%. At TEEs greater than 3,000 kcal day−1, AIM underestimated TEE by 11% compared to 31.6% by the Factorial Method. Also, at TEEs greater than 3,000 kcal day−1, the Flex‐HR method overestimated TEE by 17%.ConclusionsThis analysis demonstrated that AIM is more accurate than the Factorial Method for predicting TEE across a range of climates and physical activity levels. This suggests that AIM should be used in place of the Factorial Method for estimating human TEE. Am. J. Hum. Biol. 28:372–380, 2016. © 2015 Wiley Periodicals, Inc.
N‐Heterocyclic‐Carbene‐Catalyzed Regioselective Oxidative Ring‐Opening of Epoxides with Aromatic Aldehydes: A Facile Entry to α‐Acyloxyketones
Authors: Reddi Rambabu N. , Gontala Arjun , Prasad Pragati K. , Sudalai Arumugam 
Published: October 2015

AbstractA high‐yielding synthesis of α‐acyloxyketones using a N‐heterocyclic‐carbene (NHC)‐catalyzed, oxidative ring‐opening of epoxides with aromatic aldehydes is described. This regioselective, oxidative process utilizes a N‐bromosuccinimide (NBS)/DMSO combination as the oxidant system and Et3N as the base under mild reaction conditions.
Gezielte Anreicherung von Wirkstoffen am Knochen am Beispiel von allosterischen FPPS‐Inhibitoren
Authors: Jahnke Wolfgang , Bold Guido , Marzinzik Andreas L. , Ofner Silvio , Pellé Xavier , Cotesta Simona , Bourgier Emmanuelle , Lehmann Sylvie , Henry Chrystelle , Hemmig René , Stauffer Frédéric , Hartwieg J. Constanze D. , Green Jonathan R. , Rondeau Jean‐Michel 
Published: October 2015

AbstractDie Wirksamkeit und Verträglichkeit eines Medikaments kann verbessert werden, indem dieses gezielt an den gewünschten Wirkungsort gebracht wird. Bisphosphonate sind Prototypen derartiger Medikamente; allerdings ist ihre Affinität zum Knochen eher zu stark und lässt sich nicht modulieren, ohne die Aktivität auf das Enzym Farnesylpyrophosphat‐Synthase (FPPS) zu verlieren. Eine Konsequenz der hohen Knochenaffinität ist außerdem eine niedrige und stark variable orale Bioverfügbarkeit. Wir beschreiben hier Inhibitoren von FPPS mit einem Monophosphonat als Knochenanker, der eine moderate Affinität zum Knochen verleiht, die überdies noch moduliert werden kann. Über einen NMR‐basierten Knochenbindungstest wurde ein Zusammenhang von Struktur und Knochenaffinität etabliert. Das Konzept, Wirkstoffe durch Anhängen einer Monophosphonatgruppe und ohne Verlust der oralen Bioverfügbarkeit gezielt zum Knochen zu bringen, kann weitreichende Anwendungsmöglichkeiten auch für andere Wirkstoffe haben.
Heterometallic Rings: Their Physics and use as Supramolecular Building Blocks
Authors: McInnes Eric J. L. , Timco Grigore A. , Whitehead George F. S. , Winpenny Richard E. P. 
Published: October 2015

AbstractAn enormous family of heterometallic rings has been made. The first were Cr7M rings where M=NiII, ZnII, MnII, and rings have been made with as many as fourteen metal centers in the cyclic structure. They are bridged externally by carboxylates, and internally by fluorides or a penta‐deprotonated polyol. The size of the rings is controlled through templates which have included a range of ammonium or imidazolium ions, alkali metals and coordination compounds. The rings can be functionalized to act as ligands, and incorporated into hybrid organic–inorganic rotaxanes and into molecules containing up to 200 metal centers. Physical studies reported include: magnetic measurements, inelastic neutron scattering (including single crystal measurements), electron paramagnetic resonance spectroscopy (including measurements of phase memory times), NMR spectroscopy (both solution and solid state), and polarized neutron diffraction. The rings are hence ideal for understanding magnetism in elegant exchange‐coupled systems.
Water Interaction with Iron Oxides
Authors: Dementyev Petr , Dostert Karl‐Heinz , Ivars‐Barceló Francisco , O'Brien Casey P. , Mirabella Francesca , Schauermann Swetlana , Li Xiaoke , Paier Joachim , Sauer Joachim , Freund Hans‐Joachim 
Published: October 2015

AbstractWe present a mechanistic study on the interaction of water with a well‐defined model Fe3O4(111) surface that was investigated by a combination of direct calorimetric measurements of adsorption energies, infrared vibrational spectroscopy, and calculations bases on density functional theory (DFT). We show that the adsorption energy of water (101 kJ mol−1) is considerably higher than all previously reported values obtained by indirect desorption‐based methods. By employing 18O‐labeled water molecules and an Fe3O4 substrate, we proved that the generally accepted simple model of water dissociation to form two individual OH groups per water molecule is not correct. DFT calculations suggest formation of a dimer, which consists of one water molecule dissociated into two OH groups and another non‐dissociated water molecule creating a thermodynamically very stable dimer‐like complex.
Impact of Strand Number on Parallel β‐Sheet Stability
Authors: Kung Vanessa M. , Cornilescu Gabriel , Gellman Samuel H. 
Published: October 2015

AbstractWe have examined whether parallel β‐sheet secondary structure becomes more stable as the number of β‐strands increases, via comparisons among peptides designed to adopt two‐ or three‐stranded parallel β‐sheet conformations in aqueous solution. Our three‐strand design is the first experimental model of a triple‐stranded parallel β‐sheet. Analysis of the designed peptides by nuclear magnetic resonance (NMR) and circular dichroism (CD) spectroscopy supports the hypothesis that increasing the number of β‐strands, from two to three, increases the stability of the parallel β‐sheet. We present the first experimental evidence for cooperativity in the folding of a triple‐stranded parallel β‐sheet, and we show how minimal model systems may enable experimental documentation of characteristic properties, such as CD spectra, of parallel β‐sheets.
Synthesis and Use of a Phosphonate Amidine to Generate an Anti‐Phosphoarginine‐Specific Antibody
Authors: Fuhrmann Jakob , Subramanian Venkataraman , Thompson Paul R. 
Published: October 2015

AbstractProtein arginine phosphorylation is a post‐translational modification (PTM) that is important for bacterial growth and virulence. Despite its biological relevance, the intrinsic acid lability of phosphoarginine (pArg) has impaired studies of this novel PTM. Herein, we report for the first time the development of phosphonate amidines and sulfonate amidines as isosteres of pArg and then use these mimics as haptens to develop the first high‐affinity sequence independent anti‐pArg specific antibody. Employing this anti‐pArg antibody, we further showed that arginine phosphorylation is induced in Bacillus subtilis during oxidative stress. Overall, we expect this antibody to see widespread use in analyzing the biological significance of arginine phosphorylation. Additionally, the chemistry reported here will facilitate the generation of pArg mimetics as highly potent inhibitors of the enzymes that catalyze arginine phosphorylation/dephosphorylation.
Convenient Access to α‐Fluorinated Alkylammonium Salts
Authors: Baxter Amanda F. , Christe Karl O. , Haiges Ralf 
Published: October 2015

AbstractA series of novel α‐fluoroalkyl ammonium salts was obtained from the corresponding cyano compounds or nitriles by reaction with anhydrous HF. Room‐temperature stable trifluoromethyl ammonium salts were obtained in quantitative yield in a one‐step reaction at ambient temperature from the commercially available starting materials BrCN or ClCN. The novel cations [CF3CF2NH3]+, [HCF2CF2NH3]+, and [(NH3CF2)2]2+ were obtained from CF3CN, HCF2CN, and (CN)2, respectively, and anhydrous HF. The aforementioned fluorinated ammonium cations were isolated as room temperature stable [AsF6]− and/or [SbF6]− salts, and characterized by multi‐nuclear NMR and vibrational spectroscopy. The salts [HCF2NH3][AsF6] and [CF3NH3][Sb2F11] were characterized by their X‐ray crystal structure.
A Case Study of the Likes and Dislikes of DNA and RNA in Self‐Assembly
Authors: Zuo Hua , Wu Siyu , Li Mo , Li Yulin , Jiang Wen , Mao Chengde 
Published: October 2015

AbstractProgrammed self‐assembly of nucleic acids (DNA and RNA) is an active research area as it promises a general approach for nanoconstruction. Whereas DNA self‐assembly has been extensively studied, RNA self‐assembly lags much behind. One strategy to boost RNA self‐assembly is to adapt the methods of DNA self‐assembly for RNA self‐assembly because of the chemical and structural similarities of DNA and RNA. However, these two types of molecules are still significantly different. To enable the rational design of RNA self‐assembly, a thorough examination of their likes and dislikes in programmed self‐assembly is needed. The current work begins to address this task. It was found that similar, two‐stranded motifs of RNA and DNA lead to similar, but clearly different nanostructures.