bluuebunny/crossref_metadata_2025_split huggingface dataset:
Three‐dimensional electromagnetic imaging of upwelling fluids in the Kyushu subduction zone, Japan
Authors: Hata Maki , Oshiman Naoto , Yoshimura Ryokei , Tanaka Yoshikazu , Uyeshima Makoto 
Published: December 2014

AbstractA three‐dimensional (3‐D) lithospheric‐scale electrical resistivity model, developed using network‐magnetotelluric (network‐MT) data, contains structures associated with arc magmatism beneath Kyushu Island in the Southwest Japan arc. Kyushu Island, where the Philippine Sea Plate (PSP) subducts beneath the Eurasian plate, can be divided into northern and southern volcanic regions separated by a nonvolcanic region. Many active Quaternary volcanoes occur along the volcanic front (VF) associated with the PSP in the two volcanic regions. Our 3‐D electrical resistivity model shows three different shapes of upwelling fluid‐like conductive anomalies, indicative of either slab‐derived aqueous fluid and/or partial melt beneath the volcanic and nonvolcanic regions. A conductive anomaly in the northern volcanic region, located at some distance from the subducting PSP, extends from the surface to depths of <100 km, whereas another conductive anomaly in the southern volcanic region, located along the subducting PSP at >70 km depth, extends from the surface to depths of >100 km. In the nonvolcanic region, the upper region of a relatively conductive anomaly extends upward to a depth of ~50 km along the subducting plate. The degrees of magmatism and the relative contribution of slab‐derived fluids to the magmatism vary spatially in the one nonvolcanic and two volcanic regions.
A stability‐dependent parametrization of transfer coefficients for momentum and heat over polar sea ice to be used in climate models
Authors: Lüpkes Christof , Gryanik Vladimir M. 
Published: December 2014

AbstractThe interaction between sea ice and atmosphere depends strongly on the near‐surface transfer coefficients for momentum and heat. A parametrization of these coefficients is developed on the basis of an existing parametrization of drag coefficients for neutral stratification that accounts for form drag caused by the edges of ice floes and melt ponds. This scheme is extended to better account for the dependence of surface wind on limiting cases of high and low ice concentration and to include near‐surface stability effects over open water and ice on form drag. The stability correction is formulated on the basis of stability functions from Monin‐Obukhov similarity theory and also using the Louis concept with stability functions depending on the bulk Richardson numbers. Furthermore, a parametrization is proposed that includes the effect of edge‐related turbulence also on heat transfer coefficients. The parametrizations are available in different levels of complexity. The lowest level only needs sea ice concentration and surface temperature as input, while the more complex level needs additional sea ice characteristics. An important property of our parametrization is that form drag caused by ice edges depends on the stability over both ice and water which is in contrast to the skin drag over ice. Results of the parametrization show that stability has a large impact on form drag and, thereby, determines the value of sea ice concentration for which the transfer coefficients reach their maxima. Depending on the stratification, these maxima can occur anywhere between ice concentrations of 20 and 80%.
When Children's Knowledge of Memory Improves Children's Performance in Memory
Authors: Geurten Marie , Catale Corinne , Meulemans Thierry 
Published: December 2014

SummaryOne of the strongest hypotheses in the field of metacognition research involves the positive effect of metamemory on memory performance. However, owing to the lack of appropriate instruments to appraise knowledge of memory, few studies have examined this effect among children. This study was conducted to create and validate an instrument to assess children's metamemory knowledge and link this knowledge with their memory performance and strategy use. A sample of 166 children was given a new three‐factor metamemory interview, and its psychometric properties were investigated. Regression analyses were carried out to investigate the link between metamemory and memory performance in a subgroup of 128 children from the validation study. Results confirmed the scale's good psychometric properties and revealed its ability to predict children's memory performance. However, none of the scale's factors could predict children's use of memory strategies. Implications for the study of children's metamemory development are discussed. Copyright © 2014 John Wiley & Sons, Ltd.
Back to the Future: Similarities and Differences in Emotional Memories and Prospections
Authors: Painter Janelle M. , Kring Ann M. 
Published: December 2014

SummaryPrevious research suggests that our prospections rely, in part, upon our memories. However, less is known about the ways in which the content of memories and prospections are similar (or dissimilar) and whether this similarity varies by emotion. In the present study, we coded the content and style of participants' (n = 109) positive, negative, and neutral memory and prospection narratives. Emotional memories were more elaborated, social, and further back in time than neutral memories. By contrast, prospections varied by valence: Positive prospections included more time and place indicators and were more social and closer in time than negative prospections. Although over half of the coded content in memories and prospections matched, regardless of valence, positive memories and prospections matched more than negative. These findings suggest that people are more likely to construct positive futures that are similar to the past but are less likely to do so for negative futures. Copyright © 2014 John Wiley & Sons, Ltd.
GSTM1, GSTP1, and GSTT1 genetic variability in Turkish and worldwide populations
Authors: Karaca Sefayet , Karaca Mehmet , Cesuroglu Tomris , Erge Sema , Polimanti Renato 
Published: December 2014

ObjectiveGlutathione S‐transferase (GST) variants have been widely investigated to better understand their role in several pathologic conditions. To our knowledge, no data about these genetic polymorphisms within the Turkish population are currently available. The aim of this study was to analyze GSTM1 positive/null, GSTT1 positive/null, GSTP1*I105V (rs1695), and GSTP1*A114V (rs1138272) variants in the general Turkish population, to provide information about its genetic diversity, and predisposition to GST‐related diseases.MethodsGenotyping was performed in 500 Turkish individuals using the Sequenom MassARRAY platform. A comparative analysis was executed using the data from the HapMap and Human Genome Diversity Projects (HGDP). Sequence variation was deeply explored using the Phase 1 data of the 1,000 Genomes Project.ResultsThe variability of GSTM1, GSTT1, and GSTP1 polymorphisms in the Turkish population was similar to that observed in Central Asian, European, and Middle Eastern populations. The high linkage disequilibrium between GSTP1*I105V and GSTP1*A114V in these populations may have a confounding effect on GSTP1 genetic association studies. In analyzing GSTM1, GSTT1, and GSTP1 sequence variation, we observed other common functional variants that may be candidates for associated studies of diseases related to GST genes (e.g., cancer, cardiovascular disease, and allergy).ConclusionsThis study provides novel data about GSTM1 positive/null, GSTT1 positive/null, GSTP1*I105V, and GSTP1*A114V variants in the Turkish population, and other functional variants that may affect GSTM1, GSTT1, and GSTP1 functions among worldwide populations. This information can assist in the design of future genetic association studies investigating oxidative stress‐related diseases. Am. J. Hum. Biol. 27:310–316, 2015. © 2014 Wiley Periodicals, Inc.
Relationships of maternal and paternal anthropometry with neonatal body size, proportions and adiposity in an Australian cohort
Authors: Pomeroy Emma , Wells Jonathan C.K. , Cole Tim J. , O'Callaghan Michael , Stock Jay T. 
Published: December 2014

ABSTRACTThe patterns of association between maternal or paternal and neonatal phenotype may offer insight into how neonatal characteristics are shaped by evolutionary processes, such as conflicting parental interests in fetal investment and obstetric constraints. Paternal interests are theoretically served by maximizing fetal growth, and maternal interests by managing investment in current and future offspring, but whether paternal and maternal influences act on different components of overall size is unknown. We tested whether parents' prepregnancy height and body mass index (BMI) were related to neonatal anthropometry (birthweight, head circumference, absolute and proportional limb segment and trunk lengths, subcutaneous fat) among 1,041 Australian neonates using stepwise linear regression. Maternal and paternal height and maternal BMI were associated with birthweight. Paternal height related to offspring forearm and lower leg lengths, maternal height and BMI to neonatal head circumference, and maternal BMI to offspring adiposity. Principal components analysis identified three components of variability reflecting neonatal “head and trunk skeletal size,” “adiposity,” and “limb lengths.” Regression analyses of the component scores supported the associations of head and trunk size or adiposity with maternal anthropometry, and limb lengths with paternal anthropometry. Our results suggest that while neonatal fatness reflects environmental conditions (maternal physiology), head circumference and limb and trunk lengths show differing associations with parental anthropometry. These patterns may reflect genetics, parental imprinting and environmental influences in a manner consistent with parental conflicts of interest. Paternal height may relate to neonatal limb length as a means of increasing fetal growth without exacerbating the risk of obstetric complications. Am J Phys Anthropol 156:625–636, 2015. © 2014 The Authors American Journal of Physical Anthropology Published by Wiley Periodicals, Inc.
Calcium‐overloaded sympathetic preganglionic neurons in a case of severe sepsis with anorexia nervosa
Authors: Kinebuchi Miyuki , Matsuura Akihiro 
Published: December 2014

AimWe aimed to show the status of intracellular elements in sympathetic preganglionic neurons in an autopsy case of a 55‐year‐old woman with severe sepsis and cardiac dysfunction with anorexia nervosa.MethodsOur methods include a case report and pathological examinations of autopsied tissues using synchrotron‐generated microbeam X‐ray fluorescence analysis.ResultsA case report of severe sepsis and myocardial dysfunction. The patient had sudden short cardiac arrest without arrhythmia and sequelae, and echocardiogram showed negative inotropic change. The X‐ray fluorescence analysis of autopsied tissues indicated an unusually high concentration of cytosolic calcium in sympathetic preganglionic neurons. However, there were no significant pathological findings of damage in the heart or the cardiovascular autonomic nuclei in the central nervous system.ConclusionThe data indicate that dysfunction of the sympathetic preganglionic neurons exists in a patient of severe sepsis and cardiac dysfunction with anorexia nervosa.
Compact Coupled Graphene and Porous Polyaryltriazine‐Derived Frameworks as High Performance Cathodes for Lithium‐Ion Batteries
Authors: Su Yuezeng , Liu Yuxin , Liu Ping , Wu Dongqing , Zhuang Xiaodong , Zhang Fan , Feng Xinliang 
Published: December 2014

AbstractIt is highly desirable to develop electroactive organic materials and their derivatives as green alternatives of cathodes for sustainable and cost‐effective lithium‐ion batteries (LIBs) in energy storage fields. Herein, compact two‐dimensional coupled graphene and porous polyaryltriazine‐derived frameworks with tailormade pore structures are fabricated by using various molecular building blocks under ionothermal conditions. The porous nanosheets display nanoscale thickness, high specific surface area, and strong coupling of electroactive polyaryltriazine‐derived frameworks with graphene. All these features make it possible to efficiently depress the dissolution of redox moieties in electrolytes and to boost the electrical conductivity of whole electrode. When employed as a cathode in LIBs, the two‐dimensional porous nanosheets exhibit outstanding cycle stability of 395 mAh g−1 at 5 A g−1 for more than 5100 cycles and excellent rate capability of 135 mAh g−1 at a high current density of 15 A g−1.
Thermal and mechanical characterization of films based on poly(vinyl alcohol) and β‐lactoglobulin blends
Authors: Monasterio Nuria , Leiza Jose Ramon , Meaurio Emiliano , Sarasua Jose Ramon 
Published: December 2014

ABSTRACTIn this study, we investigated the possibility of creating easy to handle films based on poly(vinyl alcohol) (PVA) and β‐lactoglobulin (βlg) blends using the casting method. Four different variables were studied to obtain these films: different proportions of PVA and βlg, different pHs (10, 7, 5.5, and 2.5), several molecular masses of PVA (130,000, 13,000–23,000, and 2000 g/mol), and the denaturation of βlg. The first objective was to obtain films, and the second was to characterize them by differential scanning calorimetry, thermogravimetric analysis, and mechanical testing. Significant variations in behavior were found, and the variables studied modified the blends in different ways. In particular, better results were achieved when the βlg proportion was less than 30 wt %, and when a pH of 2.5 was used in conjunction with a high molecular mass (130,000 g/mol) of PVA. © 2014 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2015, 132, 41745.
On identifying the role of Sun and the El Niño Southern Oscillation on Indian Summer Monsoon Rainfall
Authors: Roy Indrani , Collins Matthew 
Published: December 2014

AbstractA solar influence on Indian Summer Monsoon (ISM) rainfall, identified in previous studies using the method of solar peak year compositing, may not be robust and can be influenced by other factors such as the El Nino Southern Oscillation (ENSO) and trends. Regression analysis, which takes into account variations across the whole solar cycle rather than just the minimum /maximum solar years, fails to detect any direct solar influence on the ISM during June–August. Regression suggests that the spatial pattern of ENSO, as imprinted in the sea level pressure in the Indian Ocean region, covering parts of Australia, has changed during the second half of last century. Thus ENSO impacts via variations in the local Hadley circulation may have played a role in modulating the ISM during that period. Finally, we discuss a possible indirect connection between the solar cycle and monsoon rainfall, which are different since the 1950s.
Improving livestock for agriculture – technological progress from random transgenesis to precision genome editing heralds a new era
Authors: Laible Götz , Wei Jingwei , Wagner Stefan 
Published: December 2014

AbstractHumans have a long history in shaping the genetic makeup of livestock to optimize production and meet growing human demands for food and other animal products. Until recently, this has only been possible through traditional breeding and selection, which is a painstakingly slow process of accumulating incremental gains over a long period. The development of transgenic livestock technology offers a more direct approach with the possibility for making genetic improvements with greater impact and within a single generation. However, initially the technology was hampered by technical difficulties and limitations, which have now largely been overcome by progressive improvements over the past 30 years. Particularly, the advent of genome editing in combination with homologous recombination has added a new level of efficiency and precision that holds much promise for the genetic improvement of livestock using the increasing knowledge of the phenotypic impact of genetic sequence variants. So far not a single line of transgenic livestock has gained approval for commercialization. The step change to genome‐edited livestock with precise sequence changes may accelerate the path to market, provided applications of this new technology for agriculture can deliver, in addition to economic incentives for producers, also compelling benefits for animals, consumers, and the environment.
Meta-analysis of superficial versus deep injection of radioactive tracer and blue dye for lymphatic mapping and detection of sentinel lymph nodes in breast cancer
Authors: Ahmed M , Purushotham A D , Horgan K , Klaase J M , Douek M 
Published: December 2014

Abstract

Background
Sentinel lymph node biopsy (SLNB) is the standard of care for axillary staging in early breast cancer. Currently, no consensus exists on the optimal site of injection of the radioactive tracer or blue dye.

Methods
A systematic review and meta-analysis of studies comparing superficial and deep injections of radioactive tracer or blue dye for lymphatic mapping and SLNB was performed. The axillary and extra-axillary sentinel lymph node (SLN) identification rates obtained by lymphoscintigraphy and intraoperative SLNB were evaluated. Pooled odds ratios (ORs) and 95 per cent c.i. were estimated using fixed-effect analyses, or random-effects analyses if there was statistically significant heterogeneity (P &lt; 0·050).

Results
Thirteen studies were included in the meta-analysis. There was no significant difference between superficial and deep injections of radioactive tracer for axillary SLN identification on lymphoscintigraphy (OR 1·59, 95 per cent c.i. 0·79 to 3·17), during surgery (OR 1·27, 0·60 to 2·68) and for SLN identification using blue dye (OR 1·40, 0·83 to 2·35). The rate of extra-axillary SLN identification was significantly greater when deep rather than superficial injection was used (OR 3·00, 1·92 to 4·67). The discordance rate between superficial and deep injections ranged from 4 to 73 per cent for axillary and from 0 to 61 per cent for internal mammary node mapping.

Conclusion
Both superficial and deep injections of radioactive tracer and blue dye are effective for axillary SLN identification. Clinical consequences of discordance rates between the two injection techniques are unclear. Deep injections are associated with significantly greater extra-axillary SLN identification; however, this may not have a significant impact on clinical management.
Comparative pharmacokinetics of three monoester‐diterpenoid alkaloids after oral administration of Acontium carmichaeli extract and its compatibility with other herbal medicines in Sini Decoction to rats
Authors: Zhang Hai , Liu Min , Zhang Wen , Chen Jun , Zhu Zhenyu , Cao Hong , Chai Yifeng 
Published: December 2014

AbstractSini decoction (SND) is an important traditional Chinese multiherbal formula, which is widely used to treat cardiovascular disease. Acontium carmichaeli (AC) is a leading herb in SND, whose main components are monoester‐diterpenoid alkaloids (MDAs). The aim of this study is to compare the pharmacokinetics of three MDAs in rat plasma after oral administration of AC extract and its compatibility with other herbal medicines in SND. A sensitive, accurate and specific LC‐MS/MS method was developed to determine the contents of three MDAs in rat plasma. Male Sprague–Dawley rats were randomly assigned to four groups: AC, AC + ZO, AC + GU and SND groups. There were significant differences in the pharmacokinetic parameters (Cmax, Tmax, t1/2, AUC(0–24), MRT and CL). Compared with the AC group, Cmax, AUC(0–24) and CL of three MDAs increased and t1/2 decreased in AC + ZO, AC + GU and SND groups. Little changed in the AC + GU group in comparison with AC + ZO group, which indicated that other ingredients in ZO may promote the absorption rate and accelerate excretion rate of MDAs. The results could be helpful for revealing the compatibility mechanism of Chinese multiherbal medicine and providing clinical medication guidance on AC and its compatibility with other herbal medicines in SND. Copyright © 2014 John Wiley & Sons, Ltd.
Up‐regulation of semaphorin 4A expression in human retinal pigment epithelial cells by PACAP released from cocultured neural cells
Authors: Ko Ji‐Ae , Hirata Junko , Yamane Ken , Sonoda Koh‐Hei , Kiuchi Yoshiaki 
Published: December 2014

Development and homeostasis of multicellular organisms require interactions between neighbouring cells. We recently established an in vitro model of cell–cell interaction based on a collagen vitrigel membrane. We have now examined the role of neural cells in retinal homeostasis by coculture of human retinal pigment epithelial (RPE) cells and neural cells on opposite sides of such a membrane. The neural cells (differentiated PC12 cells) induced up‐regulation of semaphorin 4A (Sema4A), a member of the semaphorin family of neural guidance proteins, in RPE (ARPE19) cells. This effect of the neural cells was mimicked by the neuropeptide pituitary adenylate cyclase–activating polypeptide (PACAP) and was abolished by the PACAP antagonist PACAP(6–38). Coculture with neural cells or stimulation with PACAP also induced the phosphorylation of extracellular‐signal‐regulated kinase in ARPE19 cells, and this effect of the neural cells was inhibited by PACAP(6–38). Finally, among various cytokines examined, only the amount of interleukin‐6 released by cocultures of ARPE19 and neural cells differed from that released by ARPE19 cells cultured alone. Interleukin‐6 was not detected in culture supernatants of neural cells, and the reduction in the amount of interleukin‐6 released by the cocultures compared with that released by ARPE19 cells alone was prevented by PACAP(6–38). Our findings suggest that PACAP released from retinal neural cells (photoreceptors or optic nerve cells) may regulate Sema4A expression in RPE cells and thereby contribute to the maintenance of retinal structure and function.Development and homeostasis of multicellular organisms require interactions between neighbouring cells. With the use of a coculture system based on a collagen vitrigel membrane, we have now shown that neural cells induce up‐regulation of the neural guidance protein Sema4A in RPE cells. This effect of neural cells appears to be mediated by the neuropeptide PACAP. PACAP released from retinal neural cells (photoreceptors or optic nerve cells) may thus regulate Sema4A expression in RPE cells and thereby contribute to the maintenance of retinal structure and function. Copyright © 2014 John Wiley & Sons, Ltd.