bluuebunny/crossref_metadata_2025_split huggingface dataset:
La cadena de suministros turística y su proyección en cuba. Una mirada desde la gestión de la demanda
Authors: Rodriguez Vázquez María Fernanda , Camacho Rodríguez Aliosky , Pérez Gonzáles Adrián , Velasteguí López Luis Efraín 
Published: July 2024

En la industria del turismo las investigaciones sobre la cadena de suministros constituyen una ventaja competitiva, pues dan la posibilidad de conocer lo que desea el cliente y cómo satisfacer esas necesidades. En consecuencia, una de las estrategias de la industria turística para incrementar dicha competitividad, es alcanzar una efectiva gestión en sus cadenas de suministros. Específicamente, saber gestionar y pronosticar adecuadamente demanda turística es una fuente de información que permite a los actores económicos implicados en las actividades, así como para las instituciones encargadas del destino, conocer su comportamiento y cuáles son sus elementos esenciales, que le permitan tomar decisiones a favor del crecimiento y desarrollo de los destinos turísticos. En Cuba las redes turísticas presentan innumerables deficiencias asociadas a prever correctamente el comportamiento del mercado. Por consiguiente, la investigación tuvo como objetivo proyectar la cadena de suministros turísticos del sector en el país mediante la identificación, representación y definición de los entes económicos que la integran y la colaboración entre cada uno de ellos; así como la descripción y valoración de la implicación de estos actores en la organización y gestión de la demanda turística, para hacer frente a los problemas críticos de Cuba en este sentido. Los métodos utilizados fueron análisis y síntesis, inducción y deducción, búsqueda de información, entrevistas semiestructuradas, y criterios de expertos. El principal resultado lo constituyó la identificación de los factores claves que afectan la gestión de la demanda en Cuba y los métodos para pronosticarla. El área de estudios de la investigación es el turismo, específicamente la logística
La ineficacia de la defensa técnica como causa de nulidad en el proceso penal: análisis jurídico
Authors: Bermejo Camas José Patricio , Pozo Cabrera Enrique Eugenio 
Published: July 2024

Introducción. En materia penal, la defensa técnica juega un papel crucial para garantizar un juicio justo y equitativo. La ineficacia de la defensa puede vulnerar de manera significativa el derecho a un juicio justo, destacando la importancia de explorar y comprender su impacto en la nulidad de un proceso penal. Objetivo. Este artículo analiza la relación entre la ineficacia de la defensa técnica y la nulidad de los procesos penales, identificando las principales falencias que pueden comprometer la eficacia del derecho a la defensa. Metodología. Se adoptó un enfoque cualitativo, revisando legislación relevante y jurisprudencia significativa, junto con la interpretación doctrinal sobre la defensa técnica en el contexto jurídico ecuatoriano. Resultados. Los hallazgos indican que las deficiencias en la defensa técnica, tales como la ausencia de comunicación entre el abogado y el acusado y errores en la estrategia de defensa, pueden tener como consecuencia la nulidad del proceso penal. Además, se observa que estas ineficacias reflejan una problemática más amplia relacionada con la formación y los recursos disponibles para los defensores. Conclusión. La investigación subraya la importancia de asegurar una defensa técnica efectiva como elemento esencial del debido proceso. Se propone la implementación de reformas enfocadas en la capacitación de defensores y la mejora de los recursos judiciales para fortalecer la administración de justicia y salvaguardar los derechos fundamentales del acusado. Área de estudio general: Derecho. Área de estudio específica: Derecho Procesal Penal y Litigación Oral. Tipo de estudio: Artículos originales.
Exploring the administrative burden faced by hematologists: a comprehensive study in Italy
Authors: Petruzzelli Davide , Vignetti Marco , Trasarti Stefania , Sportoletti Paolo , Della Torre Silvia , Cairoli Roberto , Leone Francesca Pia Chiara , Pompilio Giuseppe , Gullì Marco , Brown Hajdukova Eva , Integlia Davide 
Published: July 2024

Background: Administrative burdens have been identified as a major issue impacting patient care, professional practice, and the overall efficiency of healthcare systems. The aim of this study is to assess the administrative burden faced by Italian hematologists.
Methods: A cross-sectional survey that included both closed-ended quantitative questions and open-ended free text answer options was administered to 1,570 hematologists working with malignancies and members of Italian GIMEMA Foundation – Franco Mandelli ONLUS and the Italian Linfomi Foundation (FIL). The survey was conducted online from May 24 to June 30, 2023. Descriptive statistics were computed for the quantitative data to clearly summarize the responses and descriptive analysis of free text responses was carried out.
Results: Surveyed hematologists spend an average of 47.07% of their time on administrative tasks, with 63.22% (n = 110) of respondents reporting spending at least half of their time on these activities. More than half (57.47%, n = 100) reported that “Patient care” is the medical task most affected by a lack of time. Additionally, 55.17% (n = 96) reported experiencing burnout in the past 6 months, with filling out “Forms” being identified as the top contributing administrative task by 27.59% (n = 48) of respondents, followed by “Scheduling” (24.71%, n = 43) and “Managing IT system failures” (21.84%, n = 38). Nearly half of the surveyed hematologists (45.40%, n = = 79) identified patient care as the top priority requiring more time.
Conclusions: The study confirms that the administrative workload of hematologists has a significant impact on patient care, communication, and burnout risk, reducing the time available for patient care, leading to exhaustion and concern about clinical errors.
PENGARUH MEDIA PROMOSI KESEHATAN BOOKLET TERHADAP PENINGKATAN PENGETAHUAN PENDAMPING PENDERITA SKIZOFRENIA
Authors: Pertiwi Linda Ayu , Setiaji Bambang , Rahayu Dewi , Adyas Atikah , Noviansyah Noviansyah , Pratiwi Dian Utama 
Published: July 2024

Skizofrenia adalah gangguan pada otak yang menimbulkan gejala kejiwaan berupa sikap, pikiran dan perilaku yang menyimpang. Menurut WHO (2019) bahwa prevalensi pasien skizofrenia sebanyak 20 juta orang di dunia. Sedangkan di Indonesia pasien skizofrenia mencapai sekitar 400.000 orang atau sebanyak 1,7 per 1.000 penduduk. Booklet merupakan media untuk menyampaikan pesan-pesan dalam bentuk buku, baik berupa tulisan maupun gambar. Tujuan penelitian diketahuinya pengaruh media promosi kesehatan booklet terhadap peningkatan pengetahuan pendamping penderita skizofrenia di RSJ Provinsi Lampung.

Jenis penelitian kuantitatif, desain penelitian Quasy-Eksperiment (Pre-Post Test Control Group Design). Populasi penelitian seluruh keluarga pasien skizofrenia rawat inap yang melakukan kunjungan di RSJD Provinsi Lampung yaitu sebanyak 221 orang, dengan tehnik Purposive Sampling sebanyak 34 orang. Analisa data yang digunakan uji statistik Uji t-independen. Penelitian dilaksanakan pada tanggal 24 Mei â€“ 14 Juni 2023.

Hasil penelitian ada pengaruh media promosi kesehatan booklet terhadap peningkatan pengetahuan pendamping penderita skizofrenia di RSJD Provinsi Lampung (p-value = 0,000). Saran perlu dilakukan monitoring dan evaluasi pelaksanaan promosi kesehatan menggunakan media booklet pada pendamping penderita skizofrenia di RSJD Provinsi Lampung. Hal ini dilakukan agar pengetahuan pendamping penderita skizofrenia tentang penatalaksanaan penderita skizofrenia di masyarakat menjadi lebih baik, pada akhirnya berdampak pada partisipasi masyarakat untuk meningkatkan perannya dalam penatalaksanaan penderita skizofrenia di masyarakat.
Pengaruh Pelatihan Preceptor Mentor terhadap Kepuasan Mahasiswa dalam Bimbingan Praktik Klinis
Authors: Ath Thaariq Nurul Aziza , Ningsih Mahdalena Prihatin , Rahmawati Lisa 
Published: July 2024

Clinical practice learning is a learning activity held in practice settings such as hospitals, clinics, health centers and communities. Phenomenological studies state that the duties and responsibilities as a preceptor cannot be carried out optimally. Surveying student perceptions regarding the role of preceptors in practice areas, 12% stated that preceptors were less cooperative, less friendly, and less guiding; 11.3% stated that preceptors were busy with other tasks, and 15.3% stated that preceptors were busy with patients. The aim of the research was to determine the effect of preceptor mentor training on student satisfaction at the Padang DII Midwifery Study Program, Padang Ministry of Health Polytechnic. This research is quantitative research with a cross-sectional approach. The research population was clinical practice supervisors in hospitals, community health centers, and midwives' independent practice in West Sumatra. The sampling technique used total sampling with a total of 80 respondents. The research instrument is a questionnaire. The research results showed that out of a total of 80 respondents, 47 respondents (58.75%) had participated in preceptor mentor training and 38.75% of them had received student satisfaction ratings in the high category in guiding students. Conclusion : The Chi-square test result is 0.000, preceptor mentor training has an influence on student satisfaction at the DIII Midwifery Study Program, Padang Health Polytechnic, Ministry of Health, Padang in guiding clinical practice in the practice area. Recommended that the institution to collaborate with the hospital so that preceptorship training can be carried out jointly and complement each other between clinical and academic supervisors.
Efektivitas Kegiatan Pendampingan Penderita Diabetes Melitus terhadap Peningkatan Kualitas Manajemen Diri
Authors: Sidiq Rapitos , Silaban Evi Maria , Handayani Marni , Sugriarta Evino 
Published: July 2024

Diabetes mellitus (DM) is a non-communicable disease which is currently causing complex problems both globally and nationally, because apart from the high morbidity and mortality rates. The main problem for DM sufferers is non-compliance in implementing a healthy lifestyle for DM sufferers, which has an impact on their quality of life due to complications. Efforts that can be made are to improve self-management with health education. The aim of this research is to determine the effectiveness of mentoring activities in improving the quality of self-management of DM sufferers. This research uses quantitative methods, with a quasi-experimental design, one group pre-test and post-test approach. The target activity is 64 people suffering from diabetes mellitus in Gunung Talang District, Solok Regency for more than 3 months, namely 27 May - 30 September 2022. The stages of data processing are editing, coding, transfer and tabulation. Data were analyzed bivariately using paired t-test with a confidence level of 95% (α=0.05). Data is presented in the form of tables and narratives. This research found that the average pre-test self-management score was = 45.6 while the post-test score = 50.89. The average pre-test blood sugar value = 226.09mg/dl and post-test value = 220.90 mg/dl. The conclusion is that mentoring activities are effective in changing the quality of self-management, but not blood sugar levels. It is recommended that this assistance activity be continued by the community health center so that the results can be maintained in the long term so that they can improve the quality of life of DM sufferers and have an impact on reducing their blood sugar.
Bangun Rancang Sistem Informasi Berbasis Website untuk Toko Blaze Cake di Bengkayang
Authors: Hakiki Rolland Roy , Gudiato Candra 
Published: July 2024

Blaze Cake merupakan usaha mikro yang bergerak dibidang makanan, kue kering, kue basah, dll. Berdasarkan hasil wawancara dengan pemiliknya, sistem penjualan Blaze Cake saat ini adalah menerima panggilan dan SMS untuk setiap pelanggan. Selain itu, pelanggan baru kesulitan memperoleh informasi mengenai produk yang ingin dipesan untuk perorangan maupun acara. Oleh karena itu, dinilai kurang efektif dan efisien. Perancangan sistem ini menggunakan metode waterfall. Diperlukan suatu sistem informasi yang dapat menunjang penjualan, memasarkan produk, dan membantu pembeli mempelajari produk yang dijual di Blaze Cake. Oleh karena itu, dikembangkanlah sistem informasi penjualan produk Blaze Cake berbasis website. Agar dapat menyelesaikan masalah dalam penjualan, memasarkan produk yang dimilikinya, dan dapat memudahkan pembeli untuk mengetahui produk yang dijual pada Blaze Cake.
Remission from depression is associated with improved quality of life and preserved exercise capacity in adults with congenital heart disease
Authors: Fillies Brit , Stapel Britta , Lemke Lars H. , Löffler Friederike , Bauersachs Johann , Kahl Kai G. , Westhoff-Bleck Mechthild 
Published: July 2024

AimsImproved long-term survival has widened the treatment goals for adults with congenital heart disease (ACHD) by addressing parameters that impact mental well-being and exercise capacity. Depression, a frequent co-morbidity in ACHD, is linked to both. Whether successful treatment of depression also affects cardiac parameters is a matter of debate.MethodsThis prospective, cross-sectional, longitudinal study included N = 150 ACHD (mean age 35.2 ± 11.3 years, 57% male) at baseline (t0) and N = 114 at follow-up (mean follow-up: 4.8 ± 0.6 years; t1). Patients were interviewed using a structured clinical interview, and severity of depression was assessed using the Montgomery-Asperg Depression Scale (MADRS). Additional testing was performed using self-rating questionnaires concerning depression, anxiety and quality of life (QoL). Exercise capacity (VO2max) was assessed by symptom limited exercise testing.ResultsOf N = 33 patients diagnosed with depression at t0, N = 18 patients remitted and N = 15 were non-remitters. Remitters displayed significantly decreased anxiety (P = 0.013), improved global QoL (P = 0.002), and preserved VO2max (P = 0.958) at t1 compared to t0. This was associated with favourable health behaviour at t1 and stable body-mass-index. Contrarily, non-remitters reported further increased anxiety (P = 0.021) and no significant improvement in QoL (P = 0.405). VO2max declined significantly (P = 0.006) and body-mass-index increased (P = 0.004). Never-depressed patients showed no significant changes in anxiety (P = 0.415) or QoL (P = 0.211). VO2max decreased significantly (P &lt; 0.001).ConclusionIn ACHD, remission from depression is associated with better physical functioning, mental health, and QoL. The assessment and treatment of depression in ACHD emerges as an important clinical goal that should be included in a comprehensive multimodal treatment plan.
Carbon isotope chemostratigraphy of the Yucca Formation from the Solitario, Big Bend Ranch State Park, Texas
Authors: Biebesheimer E. J. , Suarez M. B. 
Published: July 2024

Introduction: The Yucca Formation is a Lower Cretaceous sedimentary unit present in West Texas. Based on its relative stratigraphic position in the Cretaceous succession of West Texas, it is expected that the Yucca Formation is of Albian and/or Aptian age. It is also expected that the carbon isotope excursions associated with OAE 1a and OAE 1b should be identified in the Yucca Formation. The goals of this project are to 1. construct a carbon isotope chemostratigraphic record of the Yucca Formation, and 2. correlate the Yucca Formation with strata of similar age using chemostratigraphy.Methods: 163 samples were collected from Big Bend Ranch State Park (BBRSP) to determine the δ13C value of bulk sedimentary organic matter.Results: C-isotope values range from −27.02‰ to −18.42‰.Discussion: Carbon isotope excursions (CIEs) that are associated with the Aptian-Albian Boundary are identified as well as CIEs associated with Oceanic Anoxic Events (1a and 1b). This allows us to conclude that the Aptian-Albian boundary is recorded within the Yucca Formation strata at about 71 m above the base of the section exposed in the Lower Shutup of the Solitario in Big Bend Ranch State Park. Regional correlation of the Yucca Formation to other chemostratigraphic records from other Cretaceous strata suggests that the Yucca Formation in BBRSP is time equivalent to the Sligo, Pine Island, James, Bexar, and a portion of the lower Glen Rose Formation on the Comanche Platform and to a portion of the lower Glen Rose Formation in Big Bend National Park.
Risk prediction models for diabetic nephropathy among type 2 diabetes patients in China: a systematic review and meta-analysis
Authors: Xu Wenbin , Zhou Yanfei , Jiang Qian , Fang Yiqian , Yang Qian 
Published: July 2024

ObjectiveThis study systematically reviews and meta-analyzes existing risk prediction models for diabetic kidney disease (DKD) among patients with type 2 diabetes, aiming to provide references for scholars in China to develop higher-quality risk prediction models.MethodsWe searched databases including China National Knowledge Infrastructure (CNKI), Wanfang Data, VIP Chinese Science and Technology Journal Database, Chinese Biomedical Literature Database (CBM), PubMed, Web of Science, Embase, and the Cochrane Library for studies on the construction of DKD risk prediction models among type 2 diabetes patients, up until 28 December 2023. Two researchers independently screened the literature and extracted and evaluated information according to a data extraction form and bias risk assessment tool for prediction model studies. The area under the curve (AUC) values of the models were meta-analyzed using STATA 14.0 software.ResultsA total of 32 studies were included, with 31 performing internal validation and 22 reporting calibration. The incidence rate of DKD among patients with type 2 diabetes ranged from 6.0% to 62.3%. The AUC ranged from 0.713 to 0.949, indicating the prediction models have fair to excellent prediction accuracy. The overall applicability of the included studies was good; however, there was a high overall risk of bias, mainly due to the retrospective nature of most studies, unreasonable sample sizes, and studies conducted in a single center. Meta-analysis of the models yielded a combined AUC of 0.810 (95% CI: 0.780–0.840), indicating good predictive performance.ConclusionResearch on DKD risk prediction models for patients with type 2 diabetes in China is still in its initial stages, with a high overall risk of bias and a lack of clinical application. Future efforts could focus on constructing high-performance, easy-to-use prediction models based on interpretable machine learning methods and applying them in clinical settings.RegistrationThis systematic review and meta-analysis was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement, a recognized guideline for such research.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/, identifier CRD42024498015.
Exploring the role of innate lymphoid cells in the periodontium: insights into immunological dynamics during orthodontic tooth movement
Authors: Pastille Eva , Konermann Anna 
Published: July 2024

BackgroundThe periodontal ligament (PDL) experiences considerable mechanical stresses between teeth and bone, vital for tissue adaptation, especially in orthodontic tooth movement (OTM). While recent research emphasizes the role of innate lymphoid cells (ILCs) in regulating sterile inflammation, their involvement in periodontal tissues during OTM remains largely unexplored.MethodsIn this study, PDL tissues from orthodontic patients (n = 8) were examined using flow cytometry to detect ILC subtypes. Transwell co-culture systems were used to expose PDL cells to mechanical strain, followed by measuring migration and ratios of sorted ILC subtypes. Statistical analyses were conducted using paired Student’s t-test, Kruskal-Wallis test, Dunn’s post-test and one-way/two-way ANOVA with Tukey’s post-test (p≤ 0.05; **, p≤ 0.01; ***, p≤ 0.001).ResultsOur findings demonstrate a significant increase in CD127+ CD161+ ILC frequencies in PDL tissues during OTM, indicating ILC involvement in sterile inflammation induced by orthodontic forces. Co-culture assays show directed migration of ILC subsets towards PDL cells and substantial proliferation and expansion of ILCs.ConclusionsThis study is the first to comprehensively investigate the role of ILCs in sterile inflammation during OTM, revealing their presence and distribution within PDL tissues’ innate immune response in vivo, and exploring their migratory and proliferative behavior in vitro. The results suggest a crosstalk between ILCs and PDL cells, potentially influencing the inflammatory response and tissue remodeling processes associated with OTM.
The current status and trends of oral bone regeneration materials: a bibliometric analysis from 1991 to 2023
Authors: Tu Ronglin , Liu Xiaoming , Xu Lin , Yao Xuemin , Zhang Ran , Li Jiadi , Zhang Wenjun , Liu Jinrong , Wu Xiuping , Li Bing 
Published: July 2024

Objectives: Due to the complexity and importance of oral bone structure, oral bone regeneration materials differ from those used in other parts of the body. To study the research trends and hotspots of oral bone regeneration materials, this paper conducts a bibliometric analysis of related papers from 1991 to 2023 (retrieved on 27 September 2023).Materials and methods: Using bibliometric methods, two visualization metric software, Citespace and VOSviewer, were used to analyze 1217 papers in SCIE, including paper analysis, author analysis, country and institution analysis, keyword analysis, and cited literature analysis.Results: ① The number of papers is generally increasing and gradually stabilizing; ② Buser D is the most influential author, while Jung, Ronald E has the highest number of papers and total citations; ③ The United States has the highest number of papers and citation frequency. The University of Bern and the University of Zurich in Switzerland are not only the institutions with the most papers, but also the institutions with the most collaborations with other institutions. ④ Many research directions have persisted for decades since their inception. The field of oral bone; regeneration materials is constantly developing and improving. In recent years, the research direction in this field may mainly focus on the role of blood cells and proteins in bone regeneration. ⑤ In recent years, the types of cited literature mainly include barrier membranes, alveolar ridge augmentation, bone graft materials, histological examination, and in vivo animal experimental models.Conclusion: The United States and Switzerland have a significant influence in the field of oral bone regeneration materials. The research hotspot in recent years is mainly on tissue engineering materials. However, traditional materials still occupy a large proportion in clinical treatment or research. In addition, the combined use of new and old materials has gradually become one of the research hotspots in this field.