bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development of a rock bolt automation attachment for the installation of improved self‐drilling friction bolts
Authors: Dolsak Wolfgang , Glantschnegg Dieter 
Published: August 2013

AbstractRock bolting attachments, special bolting rigs and semi‐automated units for the installation of conventional rock reinforcement systems, such as friction stabilizers or cable bolts, have been successfully introduced to the market in the past decades. However the increasing demand for fast and safe one‐step rock bolting procedures resulted in significant changes in the design of bolting automation units. Main issues are the integrated view on the rock bolt itself, the installation mode and the required machinery. A rock bolt automation unit for self‐drilling rock reinforcement systems must feature a reliable and easy‐to‐handle interconnection with the associated supporting machinery as well as a tough and lightweight design. In addition the integration of the automated handling into the drilling procedure requires measures on synchronization and optimization of corresponding working procedures.Entwicklung eines automatisierten Ankersetzgeräts für den Einbau von selbstbohrenden Reibankern.Ankerbohrlafetten, Ankerbohrwagen und Semi‐Automatisationen für den Einbau von konventionellem Ankerausbau, zum Beispiel Reibrohranker oder Litzenanker, kommen seit geraumer Zeit im untertägigen Bergbau zum Einsatz. Der steigende Bedarf in Bezug auf sicheren und zeitoptimierten Ankerausbau hat zu einem Umdenken in der Konstruktion von Ankerautomatisationen geführt. Das Hauptaugenmerk liegt dabei auf einer integrierten Betrachtung des jeweiligen Gebirgsankers, dem Einbauvorgang und der benötigten Gerätschaft. Eine Ankerautomatisation für selbstbohrend versetzte Gebirgsanker muss eine zuverlässige und einfach handzuhabende Schnittstelle mit dem Trägergerät sowie ein geringes Eigengewicht aufweisen. Der Einbauvorgang muss in die automatisierte Handhabung integriert werden und erfordert zusätzliche Maßnahmen hinsichtlich der Synchronisierung und Optimierung des Gesamtprozesses.
Stress‐dependent elastic wave velocity of microfractured sandstone
Authors: Katsuki Daisuke , Gutierrez Marte , Almrabat Abdulhadi 
Published: August 2013

SUMMARYA model for the stress‐dependent elastic wave velocity response of fractured rock mass is proposed based on experimental evidence of stress‐dependent fracture normal and shear stiffness. Previously proposed models and previous experimental studies on stress‐dependent fracture stiffness have been reviewed to provide a basis for the new model. Most of the existing stress‐dependent elastic wave velocity models are empirical, with model parameters that do not have clear physical meanings. To propose the new model, the rock mass is assumed to have randomly oriented microscopic fractures. In addition, the characteristic length of microfractures is assumed to be sufficiently short compared to the rock mass dimensions. The macroscopic stress‐dependent elastic wave velocity response is assumed to be attributed to the stress dependency of fracture stiffness. The stress‐dependent fracture normal stiffness is defined as a generalized power law function of effective normal stress, which is a modification of the Goodman's model. On the other hand, the stress dependency of fracture shear stiffness is modeled as a linear function of normal stress based on experimental data. Ultrasonic wave velocity responses of a dry core sample of Berea sandstone were tested at effective stresses ranging from 2 to 55 MPa. Visual observation of thin sections obtained from the Berea sandstone confirms that the assumptions made for microstructure of rock mass model are appropriate. It is shown that the model can describe the stress‐dependent ultrasonic wave velocity responses of dry Berea sandstone with a set of reasonable material parameter values. Published 2013. This article is a U.S. Government work and is in the public domain in the USA.
Acute lower urinary tract dysfunction (LUTD) following traumatic brain injury (TBI) in rats
Authors: Moody Benjamin J. , Liberman Caleb , Zvara Peter , Smith Phillip P. , Freeman Kalev , Zvarova Katarina 
Published: August 2013

AbstractAimsThe aim of this study was to assess experimental traumatic brain injury (TBI)‐induced lower urinary tract dysfunction (LUTD) by monitoring systemic and urodynamic parameters using an implantable telemetry system.MethodsA single lateral fluid percussion TBI (FP‐TBI; 3.4 atm) was administered to 10 female rats. Pressure micro‐catheters were implanted in the abdominal aorta and bladder dome for simultaneous data recording. Hemodynamic and urodynamic variables recorded 24 hr before and 24 hr after injury were analyzed and compared.ResultsTBI in the acute phase resulted in LUTD affecting bladder emptying, characterized by failure of voiding reflex, high capacity bladder, increased voided volume, prolonged intermicturition intervals, and loss of compliance. The dominant symptom was urinary retention (100%) and incontinence (60%). The effects followed a pattern of initial loss of bladder function followed by either altered recovery of reflex micturition or a period of incontinence. With a moderate injury symptoms were temporary in 90% of animals and permanent in 10% of animals. Injury produced only transient hypertension (≤1 hr) with a maximum systolic pressure of 172.64 ± 14.53 mmHg (70% of animals).ConclusionsThe results demonstrate that experimental FP‐TBI causes temporary bladder dysfunction that in more severe cases becomes permanent. Telemetry recordings revealed a sequence of events following injury that establishes moderate TBI as a risk factor for neurogenic bladder disorder. Results also suggest a correlation between lateral FP‐TBI and incontinence. Neurourol. Urodynam. 33:1159–1164, 2014. © 2013 Wiley Periodicals, Inc.
Augmentation enterocystoplasty is effective in relieving refractory ketamine‐related bladder pain
Authors: Chung Shiu‐Dong , Wang Chung‐Cheng , Kuo Hann‐Chorng 
Published: August 2013

AbstractAimsTo report our early results of augmentation enterocystoplasty (AE) for severe bladder pain associated with chronic ketamine cystitis (KC).MethodsWe performed AE for 14 patients with refractory KC‐related bladder pain, which is based on the criteria including severe bladder pain, urgency and frequency and/or upper urinary tract damage such as bilateral hydronephrosis, and contracted bladder. Every patient had been treated conservatively with medication or cystoscopic hydrodistention for at least 1 year before they had received surgical intervention. Video‐urodynamic studies were obtained before AE and 3–6 months after surgery. Outcome measurements included visual analogue score (VAS) for pain, cystometric bladder capacity (CBC), maximum urinary flow rate (Qmax), post‐void residual, and maximal detrusor pressure (Pdet). The patients' general satisfaction with regard to treatment outcome was also assessed by the Patient Perception of Bladder Condition (PPBC).ResultsA total of 4 men and 10 women underwent this procedure as indicated. The mean age was 26.7 (ranged 20–38) years old and the duration of ketamine abuse was 3.82 years (ranged 2–7). Contracted bladder was noted in all patients, hydronephrosis in nine and vesicoureteral reflux (VUR) in eight. At 3–6 months after AE, VAS was remarkably improved from baseline to the end‐point (8.29 ± 1.54 vs. 2.14 ± 1.51, P < 0.0001), CBC increased from 50.9 ± 15.7 to 309.2 ± 58.0 ml (P < 0.0001), Qmax increased from 6.94 ± 3.60 to 15.2 ± 5.51 ml/sec (P < 0.0001) and Pdet reduced from 29.7 ± 16.0 to 17.9 ± 8.2 cmH2O (P = 0.008). All patients reported marked improvement in PPBC from 6.0 to 1.4 ± 0.89 (P < 0.0001). All hydronephrosis disappeared and VUR was resolved in five patients after AE with ureteral reimplantation.ConclusionsThis pilot study demonstrated that AE is effective in relieving refractory ketamine‐related bladder pain and lower urinary tract symptoms. Neurourol. Urodynam. 33:1207–1211, 2014. © 2013 Wiley Periodicals, Inc.
Combination of foot stimulation and tolterodine treatment eliminates bladder overactivity in cats
Authors: Schwen Zeyad , Matsuta Yosuke , Shen Bing , Wang Jicheng , Roppolo James R. , de Groat William C. , Tai Changfeng 
Published: August 2013

AbstractAimsTo determine whether transcutaneous foot stimulation combined with a lower dose tolterodine would inhibit bladder overactivity more effectively than either treatment alone.MethodsCystometrograms were performed on α‐chloralose anesthetized cats (N = 6) by infusing 0.25% acetic acid (AA) to induce bladder overactivity. Foot stimulation (5 Hz) was applied at 2 and 4 times the threshold (T) intensity in volts (i.e., 2T or 4T) for inducing toe movement to inhibit bladder overactivity. Cumulative doses of tolterodine (0.003–0.3 mg/kg, i.v.) were also administered to determine the effect of combination treatment.ResultsAA irritation of the bladder significantly (P < 0.0001) reduced bladder capacity to 23.6 ± 7.1% of saline control capacity. Foot stimulation alone at 2T and 4T inhibited bladder overactivity and significantly (P < 0.0001) increased bladder capacity to 50.7 ± 6.8% and 79.0 ± 11.6% of saline control, respectively. Tolterodine alone at 0.3 mg/kg significantly (P < 0.05) increased bladder capacity to 65.6 ± 15.5% of saline control. However, when tolterodine at a threshold dose (0.3 mg/kg) was combined with foot stimulation, the bladder capacity was significantly (P < 0.05) increased to 86.2 ± 6.2% and 107.9 ± 10.6% by 2T and 4T stimulation, respectively. Complete inhibition of bladder overactivity could be achieved at a lower tolterodine dose (0.1 mg/kg) when combined with 4T stimulation (97.0 ± 11.2% of saline control). The amplitude of micturition contraction was not changed by tolterodine treatment.ConclusionsThis study suggests a novel, efficacious, non‐invasive therapy by combining foot stimulation with a lower dose tolterodine to treat bladder overactivity. It also provides the first objective evidence supporting an additive therapeutic benefit of neuromodulation and antimuscarinic combination treatment. Neurourol. Urodynam. 33:1266–1271, 2014. © 2013 Wiley Periodicals, Inc.
A stable extended FEM formulation for multi‐phase problems enforcing the accuracy of the fluxes through Lagrange multipliers
Authors: Díez P. , Cottereau R. , Zlotnik S. 
Published: August 2013

SUMMARYWhen applied to diffusion problems in a multi‐phase setup, the popular extended finite element method (XFEM) strategy suffers from an inaccurate representation of the local fluxes in the vicinity of the interface. The XFEM enrichment improves the global quality of the solution but it is not enforcing any local feature to the fluxes. Thus, the resulting numerical fluxes in the vicinity of the interface are not realistic, in particular when conductivity ratios between the different phases are very high. This paper introduces an additional restriction to the XFEM formulation aiming at properly reproducing the features of the local fluxes in the transition zone. This restriction is implemented through Lagrange multipliers, and the stability of the resulting mixed formulation is tested satisfactorily through the Chapelle–Bathe numerical procedure. Several examples are presented, and the solutions obtained show a spectacular improvement with respect to the standard XFEM. Copyright © 2013 John Wiley & Sons, Ltd.
Analysis of high‐order finite elements for convected wave propagation
Authors: Bériot Hadrien , Gabard Gwénaël , Perrey‐Debain Emmanuel 
Published: August 2013

SUMMARYIn this paper, we examine the performance of high‐order finite element methods (FEM) for aeroacoustic propagation, based on the convected Helmholtz equation. A methodology is presented to measure the dispersion and amplitude errors of the p‐FEM, including non‐interpolating shape functions, such as ‘bubble’ shape functions. A series of simple test cases are also presented to support the results of the dispersion analysis. The main conclusion is that the properties of p‐FEM that make its strength for standard acoustics (e.g., exponential p‐convergence, low dispersion error) remain present for flow acoustics as well. However, the flow has a noticeable effect on the accuracy of the numerical solution, even when the change in wavelength due to the mean flow is accounted for, and an approximation of the dispersion error is proposed to describe the influence of the mean flow. Also discussed is the so‐called aliasing effect, which can reduce the accuracy of the solution in the case of downstream propagation. This can be avoided by an appropriate choice of mesh resolution. Copyright © 2013 John Wiley & Sons, Ltd.
A stabilized discrete shear gap finite element for adaptive limit analysis of Mindlin–Reissner plates
Authors: Le Canh V. 
Published: August 2013

SUMMARYThis paper presents a numerical formulation for computation of collapse load of Mindlin–Reissner plates that uses stabilized discrete shear gap finite elements and second‐order cone programming. Displacement fields are approximated using the discrete shear gap in combination with a stabilized strain smoothing technique, ensuring that shear‐locking problem can be avoided and that accurate solutions can be obtained. The underlying optimization problem is formulated in the form of a standard second‐order cone programming, so that it can be solved using highly efficient primal‐dual interior‐point algorithm. An error indicator based on plastic dissipation will be used in the adaptive refinement scheme. Various plates with arbitrary geometries and boundary conditions are examined to illustrate the performance of the proposed procedure. Copyright © 2013 John Wiley & Sons, Ltd.
Childhood maltreatment and personality disorders in the USA: Specificity of effects and the impact of gender
Authors: Waxman Rachel , Fenton Miriam C. , Skodol Andrew E. , Grant Bridget F. , Hasin Deborah 
Published: August 2013

ABSTRACTChildhood maltreatment increases the risk for adult personality disorders (PDs), but several PDs or maltreatment types co‐occur. Specificity of maltreatment–personality associations is poorly understood. Using a representative US population sample, we identified specific associations between maltreatment types (sexual, physical and emotional abuse and physical and emotional neglect) and PDs after controlling for basic demographics, parental psychopathology, co‐occurring maltreatment types and comorbid PD. We then examined interactions of gender and maltreatment in predicting PDs. Each maltreatment type significantly predicted three–four PDs. Borderline and schizotypal PDs were most strongly predicted by sexual abuse, antisocial by physical abuse and avoidant and schizoid by emotional neglect. Specific vulnerabilities differ by gender; maltreated boys may respond with attention seeking and girls with social withdrawal. Findings highlight the importance of evaluating all forms of maltreatment even when they co‐occur and can inform development of interventions to prevent personality pathology in at‐risk children. Copyright © 2013 John Wiley & Sons, Ltd.
Predictors of treatment outcome of Inpatient Psychotherapy for Adolescents with personality pathology
Authors: Feenstra Dine J. , Laurenssen Elisabeth M. P. , Hutsebaut Joost , Verheul Roel , Busschbach Jan J. V. 
Published: August 2013

ABSTRACTLittle is known about the effectiveness of treatment programmes for personality disordered adolescents. This study investigates the treatment outcome of Inpatient Psychotherapy for Adolescents (IPA), i.e. an intensive programme for treatment refractory adolescents with personality pathology. In addition, this study examines predictors of treatment outcome. One hundred and nine adolescents admitted for treatment of their personality problems were followed up during their stay in IPA. Axis I and Axis II disorders were measured using semi‐structured interviews, and the adolescents completed several questionnaires to measure symptom severity (global indices of distress), personality styles and functioning, and quality of life at both start and 12 months after start of treatment. Patients showed improvement in level of symptom severity, personality functioning and quality of life (d ranging from 0.49 to 0.97). As for level of symptom severity, 29% of the adolescents moved into a normative range of symptom severity. Higher levels of self‐criticism significantly predicted poorer outcome in terms of symptom severity. Type of personality disorder did not predict treatment outcome. IPA is a potentially effective treatment programme for (a subgroup of) treatment refractory adolescents with personality pathology. Copyright © 2013 John Wiley & Sons, Ltd.
Attitudes of young patients with breast cancer toward fertility loss related to adjuvant systemic therapies. EORTC study 10002 BIG 3‐98
Authors: Senkus Elżbieta , Gomez Henry , Dirix Luc , Jerusalem Guy , Murray Elizabeth , Van Tienhoven Geertjan , Westenberg A. Helen , Bottomley Andrew , Rapion Jérôme , Bogaerts Jan , Di Leo Angelo , Nešković‐Konstantinović Zora 
Published: August 2013

AbstractObjectiveInfertility due to anticancer treatments is a major source of distress for young patients with cancer. A survey was performed among breast cancer patients younger than 35 years, to evaluate the acceptance of chemotherapy in the context of infertility risk.MethodsAfter obtaining written informed consent, we asked 400 premenopausal, early stage breast cancer patients aged ≤35 years to complete a short, previously pilot‐tested questionnaire. Three hundred and eighty‐nine patients were evaluable. The association between the explanatory variables and the outcome variables was assessed using logistic regression.ResultsTwo hundred and twenty‐eight (59%) participants wanted to have (more) children in the future, whereas 158 (41%) did not. Fifty‐seven (36%) of the latter did not want additional children because of fear of cancer recurrence. Thirty‐two women (8%) stated they would not accept chemotherapy should it reduce their fertility. This was dependent upon already having children, the wish to have (further) children, geographical area, disease stage, and already planned chemotherapy. One hundred and seventy‐one women who would agree to chemotherapy (48%) would accept a risk of infertility of 76–100%. This acceptance was dependent on already having children and the wish to have (more) children. Of the 355 participants (91%) accepting chemotherapy, 48 would accept it only for ≥20% gain in cure.ConclusionFor the majority of young patients with breast cancer, cure remains their first priority; for this, they are willing to accept a considerable decrease in future fertility, and only less than 10% will forego chances of cure to preserve fertility. Copyright © 2013 John Wiley & Sons, Ltd.
Amyloid fibril formation in vitro from halophilic metal binding protein: Its high solubility and reversibility minimized formation of amorphous protein aggregations
Authors: Tokunaga Yuhei , Matsumoto Mitsuharu , Tokunaga Masao , Arakawa Tsutomu , Sugimoto Yasushi 
Published: August 2013

AbstractHalophilic proteins are characterized by high net negative charges and relatively small fraction of hydrophobic amino acids, rendering them aggregation resistant. These properties are also shared by histidine‐rich metal binding protein (HP) from moderate halophile, Chromohalobacter salexigens, used in this study. Here, we examined how halophilic proteins form amyloid fibrils in vitro. His‐tagged HP, incubated at pH 2.0 and 58°C, readily formed amyloid fibrils, as observed by thioflavin fluorescence, CD spectra, and transmission or atomic force microscopies. Under these low‐pH harsh conditions, however, His‐HP was promptly hydrolyzed to smaller peptides most likely responsible for rapid formation of amyloid fibril. Three major acid‐hydrolyzed peptides were isolated from fibrils and turned out to readily form fibrils. The synthetic peptides predicted to form fibrils in these peptide sequences by Waltz software also formed fibrils. Amyloid fibril was also readily formed from full‐length His‐HP when incubated with 10–20% 2,2,2‐trifluoroethanol at pH 7.8 and 25°C without peptide bond cleavage.
The utility of PSA velocity in prediction of prostate cancer and high grade cancer after an initially negative prostate biopsy
Authors: ElShafei Ahmed , Li Yong‐Hong , Hatem Asmaa , Moussa Ayman S. , Ethan Vargo , Krishnan Nirmal , Li Jianbo , Jones J. Stephen 
Published: August 2013

AbstractBACKGROUNDProstate specific antigen kinetics (PSAK) including prostate specific antigen velocity (PSAV) and PSA doubling time (PSADT) are used as predictors of prostate cancer (PCa) therapeutic outcome, disease prognosis, and cancer‐specific mortality. However controversy persists regarding use of these parameters in cancer detection. Our aim is to evaluate PSAV as a predictor of PCa and intermediate/high grade PCa (HGPCa).METHODSWe included 682 patients that underwent repeat transrectal ultrasound guided biopsy after initial negative biopsy. Univariate and multivariate analyses as well as area under the receiver operating characteristic curve (ROC–AUC) were performed to assess predictive accuracy regarding detection of PCa and intermediate/HGPCa (Gleason score ≥ 7).RESULTSPCa was detected in 179/682 (26.24%) patients. Our univariate analysis suggested that age, total prostate volume (TPV), atypical small acinar proliferation (ASAP) and PSA indices in the form of PSA at the time of repeat biopsy (PSA2), PSAV, PSA density (PSAD2) and percent free PSA at time of repeat biopsy (%FPSA2) were all predictors of overall PCa and intermediate/HGPCa. Meanwhile, our multivariate model showed that factors associated with overall PCa and intermediate/HGPCa were age, PSAV and TPV.CONCLUSIONSIn men pursuing a second biopsy after an initial negative biopsy, PSAV was an independent predictor of overall PCa, intermediate and high grade cancer. Prostate 73:1796–1802, 2013. © 2013 Wiley Periodicals, Inc.
Characteristics and mechanism of nano‐polycrystalline La2O3 thin‐film resistance switching memory
Authors: Zhao Hongbin , Tu Hailing , Wei Feng , Xiong Yuhua , Zhang Xinqaing , Du Jun 
Published: August 2013

AbstractWe investigated the characteristics and the mechanism of Pt/La2O3/Pt resistance switching memory with a set of measurements. The La2O3 films were determined as nano‐poly‐crystalline (diameter of the nanocrystals 5–10 nm) by XRD and HRTEM analysis. The Pt/La2O3/Pt device exhibited excellent resistive switching properties, including low switching voltage (<2 V), large low/high resistance ratio (>108), and good cycling endurance property. The conduction mecha‐ nisms of the Pt/La2O3/Pt device were revealed with current–voltage characteristics, which are different in the low and high resistance states. Furthermore, XPS analysis and temperature‐dependent resistance measurement in the low resistance state showed that the conducting filaments in the Pt/La2O3/Pt device are mainly affected by oxygen defects rather than metallic La. (© 2013 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)