bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bread Supplementation with Hemp Seed Cake: A By‐Product of Hemp Oil Processing
Authors: Pojić Milica , Dapčević Hadnađev Tamara , Hadnađev Miroslav , Rakita Slađana , Brlek Tea 
Published: September 2015

AbstractHemp seed cake remaining after oil pressing was processed in the laboratory conditions to obtain hemp flour that influence the rheological properties of wheat dough, and the quality of bread was studied. The obtained hemp flour was mixed with wheat flour at different hemp/wheat flour ratios (0/100, 5/95, 10/90 and 20/80). The obtained results indicated that hemp flour affected water absorption and dough development time, and consequently bread volume, color and structural and textural properties of bread crumb regardless of the level of substitution. However, the presence of hemp flour in formulation, as being nongluten flour, did not necessarily distort all rheological properties. In this context, dough stability and dough strength were not significantly affected by the addition of hemp flour up to 10%, whereas substitution level of 20% resulted in the decrease (P < 0.05) of these parameters. Bread supplemented with hemp flour had higher nutritional value and provided elevated intake of important nutrients such as proteins and macro‐ and microelements, especially iron.Practical ApplicationsRecent scientific research indicated that hemp seed is a source of valuable nutrients, so it is recognized as one of nature's perfect balanced foods. In order to fulfill the requirements of sustainable food processing, the reutilization of food waste is a common issue especially due to the fact that food waste is rich in proteins, dietary fibers, antioxidants, colorants and other nutrients. In that sense, oilseed meals that remain after oil cold pressing have been recognized as one of the most valuable sources of proteins. One of the promising but not widely investigated cold‐pressed seed meals is that which remains after cold pressing of hemp seeds known as hemp flour. Obtained results showed that the breads supplemented with hemp flour had higher nutritional value providing elevated intake of important nutrients such as proteins and macro‐ and microelements, especially iron, while reducing the metabolizable energy from carbohydrates.
Bone histology in extant and fossil penguins (Aves: Sphenisciformes)
Authors: Ksepka Daniel T. , Werning Sarah , Sclafani Michelle , Boles Zachary M. 
Published: September 2015

AbstractSubstantial changes in bone histology accompany the secondary adaptation to life in the water. This transition is well documented in several lineages of mammals and non‐avian reptiles, but has received relatively little attention in birds. This study presents new observations on the long bone microstructure of penguins, based on histological sections from two extant taxa (Spheniscus and Aptenodytes) and eight fossil specimens belonging to stem lineages (†Palaeospheniscus and several indeterminate Eocene taxa). High bone density in penguins results from compaction of the internal cortical tissues, and thus penguin bones are best considered osteosclerotic rather than pachyostotic. Although the oldest specimens sampled in this study represent stages of penguin evolution that occurred at least 25 million years after the loss of flight, major differences in humeral structure were observed between these Eocene stem taxa and extant taxa. This indicates that the modification of flipper bone microstructure continued long after the initial loss of flight in penguins. It is proposed that two key transitions occurred during the shift from the typical hollow avian humerus to the dense osteosclerotic humerus in penguins. First, a reduction of the medullary cavity occurred due to a decrease in the amount of perimedullary osteoclastic activity. Second, a more solid cortex was achieved by compaction. In extant penguins and †Palaeospheniscus, most of the inner cortex is formed by rapid osteogenesis, resulting an initial latticework of woven‐fibered bone. Subsequently, open spaces are filled by slower, centripetal deposition of parallel‐fibered bone. Eocene stem penguins formed the initial latticework, but the subsequent round of compaction was less complete, and thus open spaces remained in the adult bone. In contrast to the humerus, hindlimb bones from Eocene stem penguins had smaller medullary cavities and thus higher compactness values compared with extant taxa. Although cortical lines of arrested growth have been observed in extant penguins, none was observed in any of the current sampled specimens. Therefore, it is likely that even these ‘giant’ penguin taxa completed their growth cycle without a major pause in bone deposition, implying that they did not undergo a prolonged fasting interval before reaching adult size.
Scar‐free cutaneous wound healing in the leopard gecko, Eublepharis macularius
Authors: Peacock Hanna M. , Gilbert Emily A. B. , Vickaryous Matthew K. 
Published: September 2015

AbstractCutaneous wounds heal with two possible outcomes: scarification or near‐perfect integumentary restoration. Whereas scar formation has been intensively investigated, less is known about the tissue‐level events characterising wounds that spontaneously heal scar‐free, particularly in non‐foetal amniotes. Here, a spatiotemporal investigation of scar‐free cutaneous wound healing following full‐thickness excisional biopsies to the tail and body of leopard geckos (Eublepharis macularius) is provided. All injuries healed without scarring. Cutaneous repair involves the development of a cell‐rich aggregate within the wound bed, similar to scarring wounds. Unlike scar formation, scar‐free healing involves a more rapid closure of the wound epithelium, and a delay in blood vessel development and collagen deposition within the wound bed. It was found that, while granulation tissue of scarring wounds is hypervascular, scar‐free wound healing conspicuously does not involve a period of exuberant blood vessel formation. In addition, during scar‐free wound healing the newly formed blood vessels are typically perivascular cell‐supported. Immunohistochemistry revealed widespread expression of both the pro‐angiogenic factor vascular endothelial growth factor A and the anti‐angiogenic factor thrombospondin‐1 within the healing wound. It was found that scar‐free wound healing is an intrinsic property of leopard gecko integument, and involves a modulation of the cutaneous scar repair program. This proportional revascularisation is an important factor in scar‐free wound healing.
‘A short time but a lovely little short time’: Bereaved parents' experiences of having a child with spinal muscular atrophy type 1
Authors: Higgs Emily J , McClaren Belinda J , Sahhar Margaret AR , Ryan Monique M , Forbes Robin 
Published: September 2015

AimSpinal muscular atrophy (SMA) type 1 is a relatively common, untreatable and invariably fatal neuromuscular disorder of early childhood. Psychosocial care is vital in management of families affected by this disease. There are few studies examining the impact of having a family member with a neuromuscular disorder, and none describing parents' experiences of having a child with SMA type 1. This study explored parents' perspectives of having a child with SMA type 1, from diagnosis to bereavement, in order to inform clinical practice by identifying aspects most meaningful to parents and to aid development of support strategies.MethodsThis qualitative study undertook thematic analysis of 11 in‐depth interviews with 13 bereaved parents of children with SMA type 1.ResultsWhile individuals' experiences were unique, common themes emerging from the data include: experiencing shock and anticipatory grief, processing feelings of responsibility and helplessness, experiencing multiple losses including the loss of future reproductive freedom, feeling supported, regaining a sense of control by making decisions about the child's life and death, and finding peace in the dying process.ConclusionThese findings highlight the importance of a multidisciplinary approach to the care of such families, including psychosocial support beginning from the time of diagnosis and continuing to bereavement. We suggest areas for further exploration, with a goal to develop family‐centred and evidence‐based psychosocial care guidelines to complement the current Standards of Care for Spinal Muscular Atrophy.
A single night of partial sleep loss impairs fasting insulin sensitivity but does not affect cephalic phase insulin release in young men
Authors: Cedernaes Jonathan , Lampola Lauri , Axelsson Emil K. , Liethof Lisanne , Hassanzadeh Sara , Yeganeh Adine , Broman Jan‐Erik , Schiöth Helgi B. , Benedict Christian 
Published: September 2015

SummaryThe present study sought to investigate whether a single night of partial sleep deprivation (PSD) would alter fasting insulin sensitivity and cephalic phase insulin release (CPIR) in humans. A rise in circulating insulin in response to food‐related sensory stimulation may prepare tissues to break down ingested glucose, e.g. by stimulating rate‐limiting glycolytic enzymes. In addition, given insulin's anorexigenic properties once it reaches the brain, the CPIR may serve as an early peripheral satiety signal. Against this background, in the present study 16 men participated in two separate sessions: one night of PSD (4.25 h sleep) versus one night of full sleep (8.5 h sleep). In the morning following each sleep condition, subjects’ oral cavities were rinsed with a 1‐molar sucrose solution for 45 s, preceded and followed by blood sampling for repeated determination of plasma glucose and serum insulin concentrations (−3, +3, +5, +7, +10 and +20 min). Our main result was that PSD, compared with full sleep, was associated with significantly higher peripheral insulin resistance, as indicated by a higher fasting homeostasis model assessment of insulin resistance index (+16%, P = 0.025). In contrast, no CPIR was observed in any of the two sleep conditions. Our findings indicate that a single night of PSD is already sufficient to impair fasting insulin sensitivity in healthy men. In contrast, brief oral cavity rinsing with sucrose solution did not change serum insulin concentrations, suggesting that a blunted CPIR is an unlikely mechanism through which acute sleep loss causes metabolic perturbations during morning hours in humans.
Screening and classification of ordinary chondrites by Raman spectroscopy
Authors: Pittarello Lidia , Baert Kitty , Debaille Vinciane , Claeys Philippe 
Published: September 2015

AbstractClassification of ordinary chondrite meteorites generally implies (1) determining the chemical group by the composition in endmembers of olivine and pyroxene, and (2) identifying the petrologic group by microstructural features. The composition of olivine and pyroxene is commonly obtained by microprobe analyses or oil immersion of mineral separates. We propose Raman spectroscopy as an alternative technique to determine the endmember content of olivine and pyroxene in ordinary chondrites, by using the link between the wavelength shift of selected characteristic peaks in the spectra of olivine and pyroxene and the Mg/Fe ratio in these phases. The existing correlation curve has been recalculated from the Raman spectrum of reference minerals of known composition and further refined for the range of chondritic compositions. Although the technique is not as accurate as the microprobe for determining the composition of olivine and pyroxene, for most of the samples the chemical group can be easily determined by Raman spectroscopy. Blind tests with ordinary chondrites of different provenance, weathering, and shock stages have confirmed the potential of the method. Therefore, we suggest that a preliminary screening and the classification of most of the equilibrated ordinary chondrites can be carried out using an optical microscope equipped with a Raman spectrometer.
Differentiation processes in FeO‐rich asteroids revealed by the achondrite Lewis Cliff 88763
Authors: Day James M. D. , Corder Christopher A. , Rumble Douglas , Assayag Nelly , Cartigny Pierre , Taylor Lawrence A. 
Published: September 2015

AbstractOlivine‐dominated (70–80 modal %) achondrite meteorite Lewis Cliff (LEW) 88763 originated from metamorphism and limited partial melting of a FeO‐rich parent body. The meteorite experienced some alteration on Earth, evident from subchondritic Re/Os, and redistribution of rhenium within the sample. LEW 88763 is texturally similar to winonaites, has a Δ17O value of −1.19 ± 0.10‰, and low bulk‐rock Mg/(Mg+Fe) (0.39), similar to the FeO‐rich cumulate achondrite Northwest Africa (NWA) 6693. The similar bulk‐rock major‐, minor‐, and trace‐element abundances of LEW 88763, relative to some carbonaceous chondrites, including ratios of Pd/Os, Pt/Os, Ir/Os, and 187Os/188Os (0.1262), implies a FeO‐ and volatile‐rich precursor composition. Lack of fractionation of the rare earth elements, but a factor of approximately two lower highly siderophile element abundances in LEW 88763, compared with chondrites, implies limited loss of Fe‐Ni‐S melts during metamorphism and anatexis. These results support the generation of high Fe/Mg, sulfide, and/or metal‐rich partial melts from FeO‐rich parent bodies during partial melting. In detail, however, LEW 88763 cannot be a parent composition to any other meteorite sample, due to highly limited silicate melt loss (0 to <<5%). As such, LEW 88763 represents the least‐modified FeO‐rich achondrite source composition recognized to date and is distinct from all other meteorites. LEW 88763 should be reclassified as an anomalous achondrite that experienced limited Fe,Ni‐FeS melt loss. Lewis Cliff 88763, combined with a growing collection of FeO‐rich meteorites, such as brachinites, brachinite‐like achondrites, the Graves Nunataks (GRA) 06128/9 meteorites, NWA 6693, and Tafassasset, has important implications for understanding the initiation of planetary differentiation. Specifically, regardless of precursor compositions, partial melting and differentiation processes appear to be similar on asteroidal bodies spanning a range of initial oxidation states and volatile contents.
Investigation of Residual Stress in 2D Plane Weave Aramid Fibre Composite Plates Using Moiré Interferometry and Hole‐Drilling Technique
Authors: Wu L. F. , Zhu J. G. , Xie H. M. 
Published: September 2015

AbstractResidual stress (RS) is crucial to the fabrications of woven composite plates and difficult to measure experimentally because of the complex structures of these plates. This study aims to investigate the RS in 2D plane weave aramid fiber composite plates using hole‐drilling technique coupled with moiré interferometry. A two‐step drilling method is proposed to solve the problems caused by the ‘peel up’ phenomenon, which facilitates the analyses of the obtained moiré patterns. The holes are deliberately selected at the intersection points of the symmetry axes of warp and weft yarns to obtain symmetrically released displacement fields. Moreover, finite element method calibration is conducted to measure RS using a model created based on the real structure of the woven composite. Based on the error analysis in numerical simulations, the less sensitive points are proposed for the RS calculation. The results show that the RS components of each specimen are compressive along the aramid yarns and tensile perpendicular to them. In addition, investigating of the influence of drilling depths on RS shows that RS decreases along the hole‐depth direction. Findings of this study are helpful for the manufacture and quality evaluation of woven aramid fibre composites.
Human neutrophil antigen‐3a antibodies induce neutrophil stiffening and conformational activation of CD11b without shedding of L‐selectin
Authors: Berthold Tom , Glaubitz Michael , Muschter Stefan , Groß Stefan , Palankar Raghavendra , Reil Angelika , Helm Christiane A. , Bakchoul Tamam , Schwertz Hansjörg , Bux Jürgen , Greinacher Andreas , Delcea Mihaela 
Published: September 2015

BACKGROUNDHNA‐3a antibodies induce severe transfusion‐related acute lung injury (TRALI) in which neutrophils play a major role. As neutrophil passage through the pulmonary microvasculature is a critical step in the pathogenesis of TRALI, we investigated the impact of HNA‐3a antibodies on two important factors that could impair granulocyte passage through lung capillaries: the elasticity of neutrophils and the expression and activation of adhesion molecules.STUDY DESIGN AND METHODSThe impact of HNA‐3a antibodies on the elasticity of neutrophils was investigated using atomic force microscopy (AFM). Neutrophils were settled on poly‐2‐hydroxyethyl‐methacrylate–coated glass slides before treatment with anti‐HNA‐3a plasma samples, control plasma, or control plasma containing formyl‐methionyl‐leucyl‐phenylalanine (fMLP). Elasticity measurements were carried out in a temperature‐controlled perfusion chamber using an atomic force microscopy (AFM) device. The impact of HNA‐3a antibodies on the surface expression of total CD11b, activation of CD11b, and L‐selectin (CD62L) shedding was investigated by flow cytometry. The functional impact of HNA‐3a antibodies on neutrophil adhesion was assessed using fibrinogen‐coated plates.RESULTSHNA‐3a antibodies induced stiffening of neutrophils (+24%‐40%; p < 0.05) to a similar extent as fMLP. This effect was blocked by treatment of neutrophils with cytochalasin D. While total surface expression of CD11b and L‐selectin on neutrophils was largely unaffected, HNA‐3a antibodies induced alloantigen‐specific activation of CD11b (+72%‐107%; p < 0.05) and increased adhesion of neutrophils to fibrinogen.CONCLUSIONAccumulation of neutrophils in the pulmonary microvasculature during severe TRALI is likely mediated by increased rigidity and CD11b‐mediated adhesion of neutrophils leading to retention of neutrophils.
Erythrocytapheresis versus phlebotomy in the maintenance treatment of HFE hemochromatosis patients: results from a randomized crossover trial
Authors: Rombout‐Sestrienkova Eva , Winkens Bjorn , Essers Brigitte A.B. , Nieman Fred H.M. , Noord Paulus A.H. , Janssen Mirian C.H. , van Deursen Cees Th.B.M. , Boonen Annelies , Reuser‐Kaasenbrood Ellen P.J.M. , Heeremans Judith , van Kraaij Marian , Masclee Ad , Koek Ger H. 
Published: September 2015

BACKGROUNDPhlebotomy is standard maintenance treatment of patients with hereditary hemochromatosis (HH). Erythrocytapheresis, which selectively removes red blood cells, provides a new, potentially more effective treatment option. Our aim was to evaluate the effectiveness of erythrocytapheresis over phlebotomy for maintenance therapy in patients with HH.STUDY DESIGN AND METHODSWe conducted a two‐treatment‐arms, randomized, crossover clinical trial, involving 46 patients, treated for 1 year with either erythrocytapheresis or phlebotomy to keep the ferritin level at not more than 50 µg/L. After 1 year, patients were switched to the other treatment modality. Primary endpoint was the number of treatment procedures per treatment year. Secondary endpoints were intertreatment intervals, several aspects of health‐related quality of life, costs, and patient discomfort as well as preference for one of both treatments.RESULTSThe mean number of required treatment procedures per treatment year was significantly higher using phlebotomy versus erythrocytapheresis (3.3 vs. 1.9; mean difference, 1.4; 95% confidence interval, 1.1‐1.7). The median intertreatment time was 2.3 times longer for erythrocytapheresis. There was no significant difference in overall health assessed by SF‐36 and EQ‐5D, respectively, between both treatments arms. The number of self‐reported swollen joints was significantly higher during phlebotomy treatment. The mean treatment costs of one treatment year were 235€ for phlebotomy versus 511€ for erythrocytapheresis. Eighty percent of patients preferred erythrocytapheresis as treatment method.CONCLUSIONErythrocytapheresis significantly reduced the number of treatment procedures per treatment year, although the mean treatment costs per year are higher in our health care system. It is the preferred treatment for the majority of patients.
Improvement of Repeated-Sprint Ability and Horizontal-Jumping Performance in Elite Young Basketball Players With Low-Volume Repeated-Maximal-Power Training
Authors: Gonzalo-Skok Oliver , Tous-Fajardo Julio , Arjol-Serrano José Luis , Suarez-Arrones Luis , Casajús José Antonio , Mendez-Villanueva Alberto 
Published: September 2015

Purpose:To examine the effects of a low-volume repeated-power-ability (RPA) training program on repeated-sprint and changeof-direction (COD) ability and functional jumping performance.Methods:Twenty-two male elite young basketball players (age 16.2 ± 1.2 y, height 190.0 ± 10.0 cm, body mass 82.9 ± 10.1 kg) were randomly assigned either to an RPA-training group (n = 11) or a control group (n = 11). RPA training consisted of leg-press exercise, twice a week for 6 wk, of 1 or 2 blocks of 5 sets × 5 repetitions with 20 s of passive recovery between sets and 3 min between blocks with the load that maximized power output. Before and after training, performance was assessed by a repeated-sprint-ability (RSA) test, a repeated-COD-ability test, a hop for distance, and a drop jump followed by tests of a double unilateral hop with the right and left legs.Results:Within-group and between-groups differences showed substantial improvements in slowest (RSAs) and mean time (RSAm) on RSA; best, slowest and mean time on repeated-COD ability; and unilateral right and left hop in the RPA group in comparison with control. While best time on RSA showed no improvement in any group, there was a large relationship (r = .68, 90% CI .43;.84) between the relative decrement in RSAm and RSAs, suggesting better sprint maintenance with RPA training. The relative improvements in best and mean repeated-COD ability were very largely correlated (r = .89, 90% CI .77;.94).Conclusions:Six weeks of low-volume (4–14 min/wk) RPA training improved several physical-fitness tests in basketball players.
Draft Genome Sequence of Veillonella tobetsuensis ATCC BAA-2400
T
Isolated from Human Tongue Biofilm
Authors: Mashima Izumi , Nakazawa Futoshi 
Published: September 2015

ABSTRACT

Here, we report the draft genome sequence of
Veillonella tobetsuensis
ATCC-BAA 2400
T
. This bacterium has the remarkable ability to form oral biofilms. The genome is predicted to encode the necessary enzymes involved in the pathway that facilitates the conversion of lactate to propionate.
Draft Genome Sequence of Brevibacillus brevis DZQ7, a Plant Growth-Promoting Rhizobacterium with Broad-Spectrum Antimicrobial Activity
Authors: Hou Qihui , Wang Chengqiang , Hou Xiaoyang , Xia Zhilin , Ye Jiangping , Liu Kai , Liu Hu , Wang Jun , Guo Haimeng , Yu Xiaoning , Yang Yanan , Du Binghai , Ding Yanqin 
Published: September 2015

ABSTRACT

Brevibacillus brevis
DZQ7 is a plant growth-promoting rhizobacterium (PGPR) isolated from tobacco rhizosphere. Here, we report the draft genome sequence of
B. brevis
DZQ7. Several functional genes related to antimicrobial activity were identified in the genome.
Complete Genome Sequence of Acinetobacter baumannii Strain B8342, a Motility-Positive Clinical Isolate
Authors: Vijaykumar Saranya , Balaji Veeraraghavan , Biswas Indranil 
Published: September 2015

ABSTRACT

Acinetobacter baumannii
is an emerging Gram-negative pathogen responsible for health care–associated infections. In this study, we determined the genome of a motility-positive clinical strain, B8342, isolated from a hospital in southern India. The B8342 genome, which is 3.94 Mbp, was generated by
de novo
assembly of PacBio long-read sequencing data.
Genome Sequences of Klebsiella variicola Isolates from Dairy Animals with Bovine Mastitis from Newfoundland, Canada
Authors: Davidson Fraser W. , Whitney Hugh G. , Tahlan Kapil 
Published: September 2015

ABSTRACT

Klebsiella variicola
was recently reported as an emerging and/or previously misidentified species associated with opportunistic infections in humans. Here, we report the draft genome sequences of
K. variicola
isolates from two animals with clinical mastitis from a dairy farm in Newfoundland, Canada.