bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Phosphine‐Mediated Domino Benzannulation Strategy for the Construction of Highly Functionalized Multiaryl Skeletons.
Authors: Xie Peizhong , Huang You , Chen Ruyu 
Published: September 2012

AbstractA diversity of polyphenyl dicarboxylates is prepared by phosphine‐mediated domino benzannulation reaction of allylic carbonates, e.g. (I), with β,γ‐unsaturated α‐ketoesters, e.g. (II).
ChemInform Abstract: Synthesis, Characterization and Catalytic Applications of Palladium Nanoparticle‐Cored Dendrimers Stabilized by Metal—Carbon Bonds.
Authors: Kumar V. K. Ratheesh , Krishnakumar Sreedevi , Gopidas Karical R. 
Published: September 2012

AbstractFour generations of the title Frechet‐type based catalysts are prepared by the simultaneous reduction of the appropriate generation diazodendrons and Pd(II) in an organic medium.
ChemInform Abstract: Stereoselective Construction of Spiro(butyrolactonepyrrolidines) by Highly Efficient Copper(I)/TF‐BiphamPhos‐Catalyzed Asymmetric 1,3‐Dipolar Cycloaddition.
Authors: Liu Tang‐Lin , He Zhao‐Lin , Tao Hai‐Yan , Wang Chun‐Jiang 
Published: September 2012

AbstractCatalytic asymmetric cycloaddition of cyclic aldimino esters is accomplished for the first time, providing facile access to spiro(butyrolactone‐pyrrolidines) containing one spiro quaternary center and three tertiary stereogenic centers.
ChemInform Abstract: Catalytic, Enantio‐ and Diastereoselective Synthesis of γ‐Butyrolactones Incorporating Quaternary Stereocenters.
Authors: Manoni Francesco , Cornaggia Claudio , Murray James , Tallon Sean , Connon Stephen J. 
Published: September 2012

AbstractThe formal cycloaddition of aryl succinic anhydrides (I) with aldehydes (II) and (V) gives rise to aryl paraconic acids with 76‐98% diastereoselectivity.
ChemInform Abstract: Reduction of 3‐Carbonyl‐Substituted 5,6‐Dicyanobenzofurans with Sodium Borohydride.
Authors: Chirkova Zh. V. , Filimonov S. I. , Abramov I. G. , Firgang S. I. , Stashina G. A. 
Published: September 2012

AbstractWhile the reduction of ketones (I) in EtOH proceeds selectively, it is nonselective in THF and leads to a mixture of different reduction products.
ChemInform Abstract: A Synthesis of Functionalized Dihydro‐1H‐pyrroles from Nef‐Isocyanide Adducts and Enamines.
Authors: Yavari Issa , Hosseinpour Reza , Pashazadeh Ramin 
Published: September 2012

AbstractHighly functionalized pyrrole derivatives are obtained which are suitable for further transformations.
ChemInform Abstract: A Smooth Rearrangement of N‐p‐Toluenesulfonyl 2‐tert‐Butyldiphenylsilylmethyl‐substituted Azetidines into N‐p‐Toluenesulfonyl 3‐tert‐Butyldiphenylsilyl‐substituted Pyrrolidines.
Authors: Narhe Bharat D. , Sriramurthy Vardhineedi , Yadav Veejendra K. 
Published: September 2012

AbstractThis ring expansion involves 1,2‐migration of silicon through a siliranium ion.
ChemInform Abstract: Phosphine‐Mediated Cascade Reaction of Azides with MBH‐Acetates of Acetylenic Aldehydes to Substituted Pyrroles: A Facile Access to N‐Fused Pyrrolo‐heterocycles.
Authors: Reddy Chada Raji , Reddy Motatipally Damoder , Srikanth Boinapally 
Published: September 2012

AbstractThe mild synthesis of the title compounds is developed by using easily accessible azides.
ChemInform Abstract: Hg(OTf)2‐Catalyzed Direct Vinylation of Tryptamines and Versatile Applications for Tandem Reactions.
Authors: Mizoguchi Haruki , Oikawa Hideaki , Oguri Hiroki 
Published: September 2012

AbstractA chemo‐, regioselective, and mild synthesis of the compounds (III) and (IX) with high functional group tolerance is developed.
ChemInform Abstract: Regioselective Condensation of Alkylidenephosphoranes to N‐Methoxy‐ and N‐Anilino‐1H Isoindole‐1,3‐(2H)‐diones.
Authors: Abdou Wafaa M. , Khidre Rizk E. , Barghash Reham F. 
Published: September 2012

AbstractSome of the monoolefinated phthalimide derivatives obtained are found to be potent antiinflammatory agents.
ChemInform Abstract: Copper‐Catalyzed Aerobic Spirocyclization of Biaryl‐N‐H‐imines via 1,4‐Aminooxygenation of Benzene Rings.
Authors: Tnay Ya Lin , Chen Cheng , Chua Yi Yuan , Zhang Line , Chiba Shunsuke 
Published: September 2012

AbstractIt provides a convenient approach to a number of azaspirocyclohexadienone derivatives.
ChemInform Abstract: Synthesis and Fungicidal Activity of Novel Pimprinine Analogues.
Authors: Zhang Ming‐Zhi , Chen Qiong , Mulholland Nick , Beattie David , Irwin Dianne , Gu Yu‐Cheng , Yang Guang‐Fu , Clough John 
Published: September 2012

AbstractPimprinine is used as the parent structure to carry out optimization with the aim of discovering synthetic analogues which possess simpler structures and improved fungicidal effects.
ChemInform Abstract: Reactivity of the Ester Group Attached Isoxazoline, Benzisoxazole, and Isoxazole: A Facile Preparation of 3‐Acyl‐Substituted These Heterocycles.
Authors: Murai Kenichi , Miyazaki Shuji , Fujioka Hiromichi 
Published: September 2012

AbstractThe reaction of methyl esters (I) and (VIII) derived from the title heterocycles with Grignard reagents or alkyl and alkyne lithium compounds is investigated.
ChemInform Abstract: A Facile Synthesis of New 4‐Amino‐2‐iminothiazoles from Unsymmetrical Thioureas
Authors: Murthy Yellajyosula Lakshmi Narasimha , Saviri Rama Mohana Rao , Ramaiah Parimi Atchuta , Nareesh Saranapu 
Published: September 2012

Abstractby cyclization with bromoacetonitriles
ChemInform Abstract: One‐Pot Sequential Multicomponent Route to 2,4‐Diaminothiazoles — A Facile Approach to Bioactive Agents for Cancer Therapeutics.
Authors: Sreejalekshmi Kumaran G. , Rajasekharan Kallikat N. 
Published: September 2012

AbstractThe title two‐step one‐pot approach employs mild reaction conditions and commercially available reagents.
ChemInform Abstract: Task‐Specific Nitrile and Azide Ionic Liquids for the Efficient One‐Pot Synthesis of 1,2,3‐Triazoles from the Aniline Derivatives.
Authors: Valizadeh Hassan , Amiri Mohammad , Khalili Elham 
Published: September 2012

AbstractAn efficient one‐pot method is reported using [bmim]N3 in place of the highly toxic NaN3 for the generation of intermediate azides.
ChemInform Abstract: Design, Synthesis and Biological Evaluation of a Novel Series of 1,3,4‐Oxadiazole Bearing N‐Methyl‐4‐(trifluoromethyl)phenyl Pyrazole Moiety as Cytotoxic Agents.
Authors: Puthiyapurayil Pushpan , Poojary Boja , Chikkanna Chandrashekhar , Buridipad Sunil Kumar 
Published: September 2012

AbstractBy means of combinatorial synthesis, a new class of heterocycles is synthesized in which the potent oxadiazole moiety is linked to a biologically active N‐methylpyrazole moiety at C‐5 and different S‐substituted alkyl groups at C‐2.
ChemInform Abstract: β‐Lapachone Analogues with Enhanced Antiproliferative Activity.
Authors: Rios‐Luci Carla , Bonifazi Evelyn L. , Leon Leticia G. , Montero Juan C. , Burton Gerardo , Pandiella Atanasio , Misico Rosana I. , Padron Jose M. 
Published: September 2012

AbstractSelective acid‐promoted cyclization of lapachols (I) affords the α‐ (III) and β‐lapachones (II), respectively.
ChemInform Abstract: Convenient Synthesis of Novel Geiparvarin Analogues with Potential Anticancer Activity via Click Chemistry.
Authors: Zhang Yikai , Lv Zhiliang , Zhong Hanyu , Geng Dongping , Zhang Mingfeng , Zhang Tao , Li Yongmei , Li Ke 
Published: September 2012

AbstractApplying the principle of bioisosteric transformation and the “click chemistry” approach affords a series of geiparvarin analogues.
ChemInform Abstract: Enantioselective Intramolecular [2 + 2] Photocycloaddition Reactions of 4‐Substituted Coumarins Catalyzed by a Chiral Lewis Acid.
Authors: Brimioulle Richard , Guo Hao , Bach Thorsten 
Published: September 2012

AbstractAlthough intramolecular cycloaddition of substrates (I) is very slow at λ < 350 nm, the addition of a chiral oxazaborolidine‐derived Lewis acid increases the reaction rate and provides access towards tetracyclic products (II) in good yields and enantioselectivities (up to 90% e.e.).
ChemInform Abstract: Regio‐ and Stereoselective Syntheses of Piperidine Derivatives via Ruthenium‐Catalyzed Coupling of Propargylic Amides and Allylic Alcohols.
Authors: Murugesan Sathiyamoorthy , Jiang Fan , Achard Mathieu , Bruneau Christian , Derien Sylvie 
Published: September 2012

AbstractThe Ru‐catalyzed ene‐yne coupling of alkynes (I) with allylic alcohols (II) in THF gives rise to cyclic enamides, [cf.
ChemInform Abstract: One‐Pot Synthesis of Phthalazines and Pyridazino‐Aromatics: A Novel Strategy for Substituted Naphthalenes.
Authors: Kessler Simon N. , Wegner Hermann A. 
Published: September 2012

AbstractThe phthalazines smoothly undergo Diels—Alder reaction with various dienophiles to allow a novel access to substituted naphthalenes such as (V).
ChemInform Abstract: 2‐Anilino‐4‐(benzimidazol‐2‐yl)pyrimidines — A Multikinase Inhibitor Scaffold with Antiproliferative Activity Toward Cancer Cell Lines.
Authors: Determann Renate , Dreher Jan , Baumann Knut , Preu Lutz , Jones Peter G. , Totzke Frank , Schaechtele Christoph , Kubbutat Michael H. G. , Kunick Conrad 
Published: September 2012

AbstractHitherto unknown title compounds of the general structure (III) are obtained by reaction of benzimidazole‐substituted enaminones (I) with suitable arylguanidinium nitrates (II).
ChemInform Abstract: Molecular Iodine‐Catalyzed Synthesis of 1,2,3,6‐Tetrahydropyrimidines.
Authors: Nagarapu Lingaiah , Vulupala Hanmanth Reddy , Venkatanarsimhaji Ch. , Bantu Rajashaker , Reddy A. Ramakrishna 
Published: September 2012

AbstractA short and efficient access to functionalized tetrahydropyrimidines (IV) proceeds under mild conditions within a few minutes and is readily amenable to parallel synthesis and generation of combinatorial libraries.
ChemInform Abstract: Synthesis, Characterization, and Fungicidal Activity of New Thienopyridopyrimidine Derivatives.
Authors: Liu Jian‐Chao , He Hong‐Wu 
Published: September 2012

AbstractStarting from the easily accessible iminophosphorane (I), a series of novel fused heterocycles (IV) is synthesized via aza‐Wittig reaction.
ChemInform Abstract: Synthesis and Some Properties of N‐Unsubstituted Pyrrolo[2,1‐c]‐1,3‐diazacycloalkano[1,2‐a]pyrazinones.
Authors: Mokrov G. V. , Likhosherstov A. M. , Lezina V. P. , Gudasheva T. A. , Bushmarinov I. S. , Antipin M. Yu. 
Published: September 2012

AbstractA number of novel heterocyclic systems is obtained from the reaction of 1‐methoxycarbonylmethyl‐2‐formylpyrroles (I) with alkylenediamines and subsequent recyclization.
ChemInform Abstract: N‐Heterocyclic Carbene‐Catalyzed Cascade Annulation Reaction of o‐Vinylarylaldehydes with Nitrosoarenes: One‐Step Assembly of Functionalized 2,3‐Benzoxazin‐4‐ones.
Authors: Sun Zhong‐Xin , Cheng Ying 
Published: September 2012

AbstractA simple and efficient method for the synthesis of the title compounds which are of potential pharmacological interest is developed.
ChemInform Abstract: Synthesis, Characterization, Antimicrobial Activities and QSAR Studies of Some 10a‐Phenylbenzo[b]indeno[1,2‐e][1,4]thiazin‐11(10aH)‐ones.
Authors: Mor Satbir , Pahal Preeti , Narasimhan Balasubramanian 
Published: September 2012

AbstractCondensation of bromoarylindandiones (I) with substituted aminobenzenethiols (II) provides access to title compounds (III) in good yields.
ChemInform Abstract: Synthesis of Coumarin‐Substituted 1,3,4‐Thiadiazine‐2‐thiones and 1,3‐Thiazoline‐2‐thiones.
Authors: Chunduru Venkata Sreenivasa Rao , Vedula Rajeswar Rao 
Published: September 2012

AbstractAcid‐promoted cyclocondensation of N‐phenylhydrazinecarbodithioic acid derivatives (IV) gives thiazoline derivatives (V), whilst analogous cyclocondensation of hydrazinecarbodithioic acid analogues (VI) affords thiadiazine derivatives (VII).
ChemInform Abstract: Meta‐B‐entacenes: New Polycyclic Aromatics Incorporating Two Fused Borepin Rings.
Authors: Levine David R. , Caruso Antony Jr. , Siegler Maxime A. , Tovar John D. 
Published: September 2012

AbstractThe title compounds exhibit slightly non‐planar core geometries with blue‐shifted spectral properties and more negative reduction potentials relative to their known para‐counterparts.
ChemInform Abstract: Enantioselective Multicomponent Synthesis of Fused 6—5 Bicyclic 2‐Butenolides by a Cascade Heterobicyclization Process.
Authors: Suero Marcos G. , De la Campa Raquel , Torre‐Fernandez Laura , Garcia‐Granda Santiago , Florez Josefa 
Published: September 2012

AbstractThe novel synthesis of the title compounds (IV) is developed from simple and readily available starting materials.
ChemInform Abstract: A Selective Seoul‐Fluor‐Based Bioprobe, SfBP, for Vaccinia H1‐Related Phosphatase — A Dual‐Specific Protein Tyrosine Phosphatase.
Authors: Jeong Myeong Seon , Kim Eunha , Kang Hyo Jin , Choi Eun Joung , Cho Alvin R. , Chung Sang J. , Park Seung Bum 
Published: September 2012

AbstractThe title compound SfBP (IV) is readily prepared by phosphorylation of known precursor (I) followed by deprotection of phosphodiester (III) with bromotrimethylsilane.
ChemInform Abstract: A Convenient Synthesis of 2‐Hydrazinoethylphosphonic Acid and Derivatives.
Authors: Cal Dariusz 
Published: September 2012

AbstractThe title compound (II) is prepared via Michael addition of hydrazine hydrate to phosphonate (I) and coupled with various carbonyl compounds to provide the corresponding condensation products including five‐ and six‐membered azaheterocyclic ethylphosphonic acids.
ChemInform Abstract: Unexpected Formation of Stannolanes and Trigonal Bipyramidal Tin Complexes by Radical Cyclization Reaction.
Authors: Kamimura Akio , Ishikawa Shingo , Noguchi Fumiaki , Moriyama Takaaki , So Masahiro , Murafuji Toshihiro , Uno Hidemitsu 
Published: September 2012

AbstractThe radical cyclization of chiral aza‐Morita—Baylis—Hillman adducts (I) with Bu3SnH yields bicyclic stannolanes (III) with high diastereoselectivity.
ChemInform Abstract: Alkylidene Branched Lupane Derivatives: Synthesis and Antitumor Activity.
Authors: Csuk Rene , Stark Sebastian , Nitsche Christoph , Barthel Alexander , Siewert Bianka 
Published: September 2012

AbstractSeveral novel alkylidene branched lupane derivatives (I)—(III), prepared using standard techniques, show significant cytotoxicity.
ChemInform Abstract: Acylprolinamides: A New Class of Peptide Deformylase Inhibitors with in vivo Antibacterial Activity.
Authors: Axten Jeffrey M. , et al. et al. 
Published: September 2012

AbstractImides, acylcarbamates, and acylureas, whose structures base on an acylprolinamide template, are synthesized and evaluated as PDF inhibitors.
ChemInform Abstract: Iron Nitride and Carbide: From Crystalline Nanoparticles to Stable Aqueous Dispersions.
Authors: Schliehe Constanze , Yuan Jiayin , Glatzel Stefan , Siemensmeyer Konrad , Kiefer Klaus , Giordano Cristina 
Published: September 2012

AbstractIron nitride and carbide nanoparticles are obtained from an aqueous slurry of iron oxide particles, urea, and agar (N2 atmosphere, 800 °C, 1 h).
ChemInform Abstract: The Discovery of N‐Cyclopropyl‐4‐methyl‐3‐ [6‐(4‐methylpiperazin‐1‐yl)‐4‐oxoquinazolin‐3(4H)‐yl]benzamide (AZD6703, a Clinical p38α MAP Kinase Inhibitor for the Treatment of Inflammatory Diseases.
Authors: Cumming John G. , et al. et al. 
Published: September 2012

AbstractSequential conversion of two embedded aniline functionalities in the bisamide series to a quinazolinone and an N‐cyclopropyl reverse amide provide a potent, selective, and orally available series of the title inhibitors.
ChemInform Abstract: MK‐8825: A Potent and Selective CGRP Receptor Antagonist with Good Oral Activity in Rats.
Authors: Bell Ian M. , et al. et al. 
Published: September 2012

AbstractCompound (I), an analogue of the clinically tested calcitonin gene‐related peptide receptor antagonist MK‐3207, is identified as a CGRP receptor antagonist with suitable potency, selectivity, and pharmacokinetics to interrogate the in vivo effects of receptor blockade.
ChemInform Abstract: Tetrathiafulvalene Vinylogues as Versatile Building Blocks for New Organic Materials
Authors: Zhao Yuming , Chen Guang , Mulla Karimulla , Mahmud Ilias , Liang Shuai , Dongare Prateek , Thompson David W. , Dawe Louise N. , Bouzan Stephen 
Published: September 2012

AbstractReview: 96 refs.
Lack of Enantioselectivity in the SULT1A3‐catalyzed Sulfoconjugation of Normetanephrine Enantiomers: An In Vitro and Computational Study
Authors: Grouzmann Eric , Gualtierotti Jean‐Baptiste , Gerber‐Lemaire Sandrine , Abid Karim , Brakch Noureddine , Pedretti Alessandro , Testa Bernard , Vistoli Giulio 
Published: September 2012

ABSTRACT(1R)‐Normetanephrine is the natural stereoisomeric substrate for sulfotransferase 1A3 (SULT1A3)‐catalyzed sulfonation. Nothing appears known on the enantioselectivity of the reaction despite its potential significance in the metabolism of adrenergic amines and in clinical biochemistry. We confronted the kinetic parameters of the sulfoconjugation of synthetic (1R)‐normetanephrine and (1S)‐normetanephrine by recombinant human SULT1A3 to a docking model of each normetanephrine enantiomer with SULT1A3 and the 3′‐phosphoadenosine‐5′‐phosphosulfate cofactor on the basis of molecular modeling and molecular dynamics simulations of the stability of the complexes. The KM, Vmax, and kcat values for the sulfonation of (1R)‐normetanephrine, (1S)‐normetanephrine, and racemic normetanephrine were similar. In silico models were consistent with these findings as they showed that the binding modes of the two enantiomers were almost identical. In conclusion, SULT1A3 is not substrate‐enantioselective toward normetanephrine, an unexpected finding explainable by a mutual adaptability between the ligands and SULT1A3 through an “induced‐fit model” in the catalytic pocket. Chirality, 25:28‐34, 2012.© 2012 Wiley Periodicals, Inc.
Direct N‐Arylation of Azaheterocycles with Aryl Halides under Ligand‐free Condition
Authors: Yang Qichao , Wang Yufang , Zhang Baoji , Zhang Mingjie 
Published: September 2012

AbstractA simple and efficient CN cross‐coupling method of aryl halides with various heterocycles was reported, by using 10 mol% of CuI as catalyst and 1.2 equiv. NaH as base. Aryl iodides, aryl bromides and many substituted aryl chlorides could efficiently react with heterocycles, providing variety of N‐arylated products in good to excellent yields. The ligand‐free catalyst system was stable in air and could be readily reused.
Slightly Cross‐Linked Polyrotaxanes Made by Linking α‐Cyclodextrins Entrapped in Polyrotaxanes Using Hexamethylene Diisocyanate
Authors: Li Shuo , Wang Jin , Jiang Lan , Ye Lin , Zhang Aiying , Feng Zengguo 
Published: September 2012

AbstractIn this study polyrotaxane (PR)‐based triblock copolymers were first synthesized via the atom transfer radical polymerization (ATRP) of N‐isopropylacrylamide initiated with the self‐assembly of a distal 2‐bromoisobutyryl end‐capped Pluronic 17R4 with a varying amount of α‐cyclodextrins (α‐CDs) in the presence of CuCl/PMDETA at 25°C in aqueous solution. The α‐CDs entrapped on the copolymer chain were then linked with hexamethylene diisocyanate to give rise to novel slightly cross‐linked polyrotaxanes (SCPRs) in DMF at 45°C. The structures of the PR‐based triblock copolymers and SCPRs were characterized by 1H NMR, 13C CP/MAS, GPC and TGA analyses. The number‐average molecular weight of the resulting SCPRs was nearly three and five times of their precursor after linking with a low polydispersity index range of 1.08–1.28. The thermo‐responsive transition of both PR‐based supramolecular polymers in aqueous solution was demonstrated by turbidity measurements and the self‐aggregated morphologies were also evidenced by TEM observations.
A Unique Solvent‐Induced Structural Transformation of Two Acentric [Zn2(H2O)(Hdtim)2] Isomers
Authors: Dang Qinqin , Ji Fang , Zhang Xianming 
Published: September 2012

AbstractSolvent‐induced structural transformation was observed in two layered supramolecular isomers of [Zn2(H2O)(Hdtim)2] (H3dtim=4,5‐ditetrazoyl‐imidazole). Structural analyses revealed that the two isomers have the similar geometry of Zn, coordination mode of Hdtim2−, and topology. Their structural differences only arise from different arrangement of the layers which seemingly corresponds to cooperative clockwise and counter‐clockwise 90° rotation of the adjacent layers. This is a quite unique solvent‐dependent supramolecular isomerism in coordination polymers.
Synthesis and Application of a Full Water‐Soluble and Red‐Emitting Chemosensor Based on Phenoxazinium for Copper(II) Ions
Authors: Yan Baolong , Sun Ru , Ge Jianfeng , Xu Yujie , Zhang Qianqian , Yang Xuebo , Lu Jianmei 
Published: September 2012

AbstractA phenoxazinium‐based chemosensor (1) bearing di(2‐picolyl)amine unit was successfully synthesized. The result shows that it is a red‐emitting and full water‐soluble chemosensor for the selective detection of Cu2+ in pure water. The fluorescence on‐off mechanism was studied by ab initio calculations. To confirm the suitability of 1 for biological applications, it was employed in the fluorescence detection of the intracellular Cu2+ with cultured KB cells. The results indicated that 1 had good membrane permeability and could be useful for the fluorescence microscopic imaging.
Accelerated Curing Speed of Ethyl α‐Cyanoacrylate by Polymer with Catecholamine Groups
Authors: Zhang Feng , Liu Siwei , Zhang Yi , Xu Jiarui , Wei Yen 
Published: September 2012

AbstractFour kinds of poly(ethylene glycol) (PEG) derivatives with the similar backbone and different side groups have been synthesized successfully. When both catecholamine and double bond are tethered to polymer backbone, i.e., the PEG backbone, simultaneously, the polymer can accelerate the curing speed of ethyl α‐cyanoacrylate (commercially available as 502) greatly under the same conditions (the curing time of such system is no more than 5 s). Probably this is due to the autoxidation of catecholamines. Through the redox‐cycling, catecholamines can produce, collect free radicals, and thus initiate the free radical polymerization. Due to the fast‐curing of such material when mixed with α‐cyanoacrylate, we could design and develop a new bicomponent super bioglue used in the dentistry or other bioenvironment requiring super fast settlement for further surgical operations.
Advantage of Fluorescence Correlation Spectroscopy for the Study of Polyelectrolytes
Authors: Jia Pengxiang , Gong Yongkuan , Wang Shengqin , Zhao Jiang 
Published: September 2012

AbstractThe advantage of fluorescence correlation spectroscopy to study single chain behavior of polyelectrolytes has been demonstrated by checking the coil‐to‐globule transition of poly 2‐vinylpyridine with the change of pH value in aqueous solution. The ultra‐high sensitivity of FCS allows measurement at extreme dilution where the effect of electrostatic interaction between the chains is greatly suppressed. The results exposed first‐order conformation transition of P2VP as detected by FCS while inter‐chain aggregation occurred in the experiments of dynamic light scattering.
Asymmetric Aldol Reaction Catalyzed by Modularly Designed Organocatalysts
Authors: Sinha Debarshi , Mandal Tanmay , Gogoi Sanjib , Goldman Joshua J. , Zhao John Cong‐gui 
Published: September 2012

AbstractThe self‐assembly of the precatalyst modules, which are amino acids and cinchona alkaloid derivatives, leads to the direct formation of the desired organocatalysts without any synthesis. These modularly designed organocatalysts (MDOs) may be used for catalyzed asymmetric aldol reaction. Depending on structure of the aldehyde substrates, the corresponding aldol products may be obtained in mediocre to excellent ee values (up to 92% ee) with moderate diastereoselectivities (up to 79:21 dr).