bluuebunny/crossref_metadata_2025_split huggingface dataset:
Familles et thérapeutes : éprouver ensemble la situation de handicap
Authors: Lopez-Minotti Véronique , Maraquin Carine 
Published: August 2024

« Familles et thérapeutes : éprouver ensemble la situation de handicap. » Dans cet article, deux psychologues cliniciennes explorent l’épreuve que constitue la rencontre avec le handicap, au sein d’une famille à l’arrivée d’un enfant, puis en thérapie. Ces réflexions sont illustrées par une thérapie familiale auprès d’une jeune femme en situation de handicap. L’entrée en institution pour adultes est l’occasion de revisiter les effets de la fragilité de l’identification primaire, causée par le handicap, et de réaménager les liens familiaux vers plus de subjectivation et d’individualisation. Le soin psychique familial est considéré ici comme un outil de réaffiliation.
Female Leadership in Pediatric Ophthalmology: A Descriptive Analysis
Authors: Lam Laurel , Nelson Leonard B. , Bayraktutar Betul N. , Lee Karen E. 
Published: August 2024

Purpose
To examine female representation among current chiefs of pediatric ophthalmology services of academic medical centers and children's hospitals, as well as program directors of ophthalmology residency and pediatric ophthalmology fellowship programs in the United States.

Methods

Data collection for this cross-sectional study occurred between December 2023 and February 2024, using publicly available sources to compile a list of academic medical centers and children's hospitals, as well as ophthalmology residency programs and pediatric ophthalmology fellowship programs that participated in the 2023–2024 San Francisco Match. Chi-squared analyses were performed using Excel 2021 software, where a
P
value less than .05 was considered statistically significant.

Results

Of the dedicated pediatric ophthalmology services across academic medical centers and children's hospitals in the United States, 38.3% (64/167) are led by a female chief. Female representation was greater at children's hospitals (40.0%, 36/90) than at academic medical centers (36.4%, 28/77), although no significant difference was observed (
P
= .69). Gender distribution was near equivalent at both academic training program levels, with slightly more female directors of fellowship programs (45.7%, 21/46) than ophthalmology residency programs (42.3%, 52/123) (
P
= .33).

Conclusions
The authors report near equivalent female representation in the leadership of academic training programs at the residency and fellowship level. However, the proportion of female pediatric ophthalmology division chiefs lags behind the actual gender composition of the workforce. Given the increasing prevalence of female pediatric ophthalmologists, promotion of concordant representation in leadership is necessary to reflect the changing sociocultural landscape and to close the gender gap.

[
J Pediatr Ophthalmol Strabismus
. 2024;61(6):391–396.]
Botulinum Toxin A Augmentation of Strabismus Surgery for Large-Angle Strabismus: A Retrospective Case Series and Literature Review
Authors: Dikkaya Çiçek Funda , Karaman Erdur S Sevil , Karaaslan Nisa 
Published: August 2024

Purpose
To report the results of botulinum toxin A (BTA)–augmented bilateral recession or monocular recession/resection surgery in a case series of patients with large-angle strabismus and review the relevant literature.

Methods
This retrospective study reviewed the medical records of 24 patients treated with BTA-augmented strabismus surgery for large-angle horizontal strabismus (55 prism diopters or greater) with a minimum 6-month follow-up. Patients underwent unilateral recession-resection or bilateral rectus muscle recession surgery with intraoperative BTA injection into the recessed muscle(s). Main outcome measures were postoperative angle of deviation and success rate, defined as a final deviation of 10 prism diopters or less.

Results
Of 24 patients (20 esotropia, 4 exotropia), the mean age was 9.2 years (range: 1 to 64 years). Mean preoperative deviation was 61.2 prism diopters for esotropia and 66.2 prism diopters for exotropia. Mean final postoperative deviation was 6.6 prism diopters for esotropia and 14.5 prism diopters for exotropia. Successful outcomes were achieved in 75% of patients with esotropia and 50% of patients with exotropia.

Conclusions
BTA augmentation of conventional strabismus surgery dosages is a promising approach for managing large-angle strabismus, particularly esotropia. Optimal patient selection and follow-up are needed to maximize surgical success rates.

[
J Pediatr Ophthalmol Strabismus
. 2025;62(1):5–11.]
RESEARCH INTO A STABLE DIFFUSION-BASED HUMAN-MACHINE-HUMAN TEACHING MODEL FOR ARCHITECTURAL DESIGN COURSES
Authors: Du Sheng , Lu Xiaoyue , Chen Zimo , Cai Zixiao , Chen Lei 
Published: August 2024

ABSTRACT
Conventional methods of teaching architectural design have flaws like fuzzy information exchange, limitations of thought dispersion, and disconnection of theory and practice because of the different cognitive levels of teachers and students. This paper explores the interactive and collaborative “human-machine-human” mode of utilizing Stable Diffusion image generation technology to teach architectural design and achieve artificial intelligence. To enhance the quality and effectiveness of instruction, the model uses artificial intelligence for image generation, optimization, and presentation in accordance with the three stages of architectural design teaching that are developed in this paper. Mainly using the Northeastern University youth hostel design course as an example, this paper compares the new “human-machine-human” mode with the traditional “human-human” mode, assesses the necessity and viability of the AI intervention, and offers examples for future architectural course teaching reform and the comprehensive integration of AI and architecture. In the interim, it offers resources and recommendations for the deep integration of AI and architecture, as well as recommendations for future teaching reform of architecture courses.
RESILIENCE OF GREEN BUILDING SUPPLY CHAIN: CAPABILITIES, RISKS AND INFLUENCE MECHANISM
Authors: Jiang Yongsheng , Zhang Yunjia , Yeganeh Armin , Zhao Dong 
Published: August 2024

ABSTRACT
Green buildings are more effective in saving energy and reducing carbon dioxide emissions than conventional buildings. However, the long-term development of green buildings depends heavily on the resilience of their supply chain. This study examines how capability factors (readiness, response, and recovery) and risk factors (technological, organizational, and environmental) interact to influence the resilience of the green building supply chain, using a third-order partial least squares structural equation model. The results indicate that response capability and technological risk significantly impact resilience, while readiness capability mitigates organizational and environmental risks. The study suggests three strategies to enhance supply chain resilience: strengthening readiness capabilities and increasing resistance to organizational or environmental risks. The findings provide green building project managers with practical insights and tools to make informed decisions that improve supply chain resilience.
A Study of Neurological Involvement in Dengue and Chikungunya Infection
Authors: Gulati Shipra , Duggu Samrasimha Reddy , Chawla Kunal , Dessai Rishikesh , Jain Sunil 
Published: August 2024

Introduction:
Chikungunya virus (CHIKV) and dengue fever have been reported for recent epidemics worldwide, with varied clinical involvement. Chikungunya was first reported to affect the nervous system in the 1960s. The clinical profile of dengue with multi-organ involvement is varied with reported involvement of the central nervous system in some.

Aim:
The aim of this study was to study the frequency and pattern of neurological involvement in patients admitted with dengue and chikungunya in a tertiary care hospital.

Materials and Methods:
Patients admitted with confirmed chikungunya and dengue were evaluated clinically and investigations were enrolled in the study. Patients with preexisting neurological issues, obvious metabolic, vascular, or septic causes for neurological involvement were excluded from the study.

Results:
A total of 309 patients with chikungunya were included in the study. Out of these, 11 (3.56%) patients were found to have neurological involvement. The most common presentations were altered sensorium (100%) followed by headache (81.81%). The relative risk of mortality in patients with neurological involvement due to chikungunya was 7.96. A total of 443 patients with dengue fever were enrolled in the study. Out of these, 5 (1.10%) patients were found to have neurological involvement. The most common presentations were altered sensorium and headache (100%), followed by vomiting (80%). The relative risk of mortality in patients with neurological involvement due to dengue was 5.15.

Conclusion:
The recent epidemic of chikungunya and dengue virus infections was associated with various neurological complications. Neurological involvement of chikungunya and dengue was identified to be a bad prognostic factor with significantly higher mortality.

Limitations:
This is a single center study, involving only the patients admitted to the hospital. Furthermore, being an observational study, follow-up could not be done to look for neurological sequelae.
Effectiveness of the Practice of Standardized Handover Process Using a Checklist in the Postanesthesia Care Unit: An Observational Study
Authors: Dubey Samriddhi , Santha Neeta 
Published: August 2024

Context:
Patient handovers without any structured checklist may omit essential information that might have undesirable consequences for patients.

Aim:
We sought to determine the effectiveness of a structured postanesthesia care handover (PACH) checklist in the postanesthesia care unit (PACU) to reduce adverse clinical outcomes.

Setting and Design:
A single-center, prospective, pre–postimplementation study was conducted.

Materials and Methods:
Moreover, post-PACH checklist implementation data were collected from 130 participants (n = 65 in each group) by an independent observer. Data analysis was performed using the SPSS (25.0) version (IBM SPSS statistics). The Chi-square test was used to compare the dichotomous response.

Results:
A statistically significant reduction in hypoxemia (21.5% vs. 0; P < 0.001) was observed in the postimplementation group. There were significant improvements in patient information (P < 0.01), reduction in variations in hemodynamic parameters (P < 0.01), and improvement in the quality of information transferred concerning surgical procedures (P < 0.01). The number of phone calls to consultants was significantly lower in the PACH group.

Conclusion:
Implementation of the PACH checklist was associated with no hypoxemic events in PACU by improving the quality of communication. The implementation of a structured checklist in PACU should be mandatory in the postoperative intensive care unit.
Diagnostic Utility of High-resolution Esophageal Manometry and Its Correlation with Symptoms
Authors: Musunuri Balaji , Pemmada Vikas , Bhat Ganesh , Shetty Athish , Shetty Shiran , Pai Ganesh C. 
Published: August 2024

Background:
Primary esophageal motility disorders present with a spectrum of symptoms where manometry plays an important role. We designed this study to evaluate the utility of esophageal manometry among various symptoms.

Materials and Methods:
This is a single-center observational study conducted over 5 years in a tertiary referral center. A total of 564 patients who underwent high-resolution esophageal manometry (HREM) using a 16-channel water perfusion system were included in the study. Their clinical profile and manometric findings, as per the Chicago classification version 4.0, were recorded, and the diagnostic utility of HREM with respect to symptoms was studied.

Results:
Motility disorders were identified in 48.8% of patients, the most common being Achalasia cardia (32.4%). Dysphagia (55.5%) was the most common indication of manometry, followed by gastroesophageal reflux disease (GERD) (34.9%), chest pain (6.2%), and symptoms such as belching, globus, and hiccoughs (3.4%). Among those who were re-classified from Chicago classification v3.0 to v4.0, 21.2% had a newer diagnosis. Among the patients with dysphagia, HREM revealed the highest yield of detecting an abnormal esophageal motility test (70.6%); meanwhile, this yield was much lower in those with GERD (21.8%), chest pain (22.8%), and other symptoms (15.7%). The most common finding among those with dysphagia was Achalasia cardia (55.9%), while the study was normal among those with GERD (78.1%), chest pain (77.1%), and other symptoms (84.2%). The sensitivity and specificity of dysphagia for major motility disorders were 65% and 91%, respectively, with a positive predictive value of 90%.

Conclusion:
HREM has high accuracy and a good diagnostic yield among patients with dysphagia, with the most common finding being Achalasia cardia.
In endometrial carcinoma, Ghrelin expression has a diagnostic role, and signal transductors and activators of transcription 5 can be a therapeutic target
Authors: Khalil El Zahraa I. , Shaheen Kareem , Mohammed Enas M. , Mohamed Fatma E.Z.A. 
Published: August 2024

Abstract

Background and objective
Endometrial carcinoma was ranked the sixth most common female cancer worldwide. Previous studies reported that Ghrelin–signal transductors and activators of transcription 5 (STAT5) axis could modulate many tumors’ behavior. Therefore, we investigated the expressions of Ghrelin and STAT5 in endometrioid carcinoma (EC). Moreover, we tried to find a diagnostic marker to differentiate atypical hyperplasia (AH) from well-differentiated EC.

Patients and methods
One hundred-eight formalin-fixed and paraffin-embedded specimens were cut, and each specimen was stained with STAT5 and Ghrelin separately using immunohistochemistry.

Results
STAT5 expression was detected in 78.6% of EC. This expression was significantly increased with increasing EC grade (P=0.04) and myometrial invasion depth (P=0.01). In contrast, there was a decrease in Ghrelin expression with lesion progression from cyclic endometrium, and endometrial hyperplasia to EC, which was statistically significant (P=0.002). Moreover, a negative association was noticed between Ghrelin expression and histological grades, depth of myometrial invasion, presence of lymph node metastasis, and tumor stage (P=0.01, 0.05, 0.003, and 0.002, respectively).

Conclusion
STAT5 is associated with differentiation and invasion in EC and can be targeted for therapeutic management. Additionally, Ghrelin can be a sensitive marker to distinguish AH and well-differentiated EC.
Adjunctive aspiration technique for the surgical management of deep orbital cavernous hemangioma
Authors: Cheng Li-Wei , Wei Yi-Hsuan , Liao Shu-Lang 
Published: August 2024

Abstract
To propose a needle aspiration technique for the surgical removal of orbital cavernous hemangioma. In this retrospective case series, we enrolled 13 patients with orbital cavernous hemangioma, who underwent excisional surgery assisted with needle aspiration technique from June 2013 to April 2022. Preoperative symptoms, clinical examination, and imaging features were recorded. Surgical outcomes, including the improvement of visual acuity, proptosis, and ocular motility, were assessed. Postoperative complications were also reported. There were 11 female and two male patients, with a mean age of 50.2 ± 8.0 years (range: 38–61 years). The most common symptom was proptosis (12 cases, 92%), followed by blurred vision (6 cases, 46%). The diameter of the lesions was between 1.8 and 3.2 cm on preoperative imaging. The surgical approaches included sub-brow orbitotomy in 11 patients and the inferior transconjunctival approach in two cases. All the tumors were removed successfully after needle aspiration of 1–3 cc of intralesional blood to reduce the tumor size. Preoperative proptosis, blurred vision, and diplopia improved after the surgery in all cases. There were no serious complications or recurrence of orbital hemangioma. The study presented an effective application of the needle aspiration technique in the surgical management of orbital cavernous hemangioma. Such an innovative method can bring significant benefits, especially for those with large cavernous hemangioma within the deep orbital region.
Systemic effects of anti-VEGF intravitreal injection in patients with age-related macular degeneration: A multi-institutional real-world study
Authors: Lin Tzu-Yi , Hsieh Yi-Ting , Garg Sunir J , Chen Lee-Jen , Chen Kuan-Jen , Wu Wei-Chi , Lai Chi-Chun , Hwang Yih-Shiou , Kang Eugene Yu-Chuan 
Published: August 2024

Abstract

Purpose:
In individuals aged >50 years, age-related macular degeneration (AMD) is the leading cause of irreversible blindness. Intravitreal injections of antivascular endothelial growth factor (VEGF) agents (bevacizumab, ranibizumab, and aflibercept) show good efficacy and similar incidences of systemic adverse events (SAEs). However, comparative studies between agents are limited. Our study aimed to compare the real-world SAE risks of bevacizumab, ranibizumab, and aflibercept users.

Methods:
This retrospective cohort study identified new bevacizumab, ranibizumab, and aflibercept users in a multi-institutional database in Taiwan between 2014 and 2019. Inverse probability of treatment weights (IPTW) with propensity scores was conducted to achieve homogeneity among groups. The Fine and Gray model was utilized to estimate the subdistribution hazard ratio and 95% confidence interval.

Results:
This study included 701 bevacizumab, 463 ranibizumab, and 984 aflibercept users. After IPTW, all covariates were well-balanced. All three anti-VEGF agents had a low and comparable number per 100 person-years of major adverse cardiac events, heart failure, thromboembolic events, major bleeding, all-cause admission, and all-cause death (all P > 0.05). No significant differences in long-term change of systolic and diastolic blood pressure, low-density lipoprotein, estimated glomerular filtration rate, and alanine transaminase (all P for interaction > 0.05) were observed among groups.

Conclusion:
Bevacizumab, ranibizumab, and aflibercept had a good systemic safety profile in this study. All groups showed a low and similar SAE risk and no differences in their long-term change of laboratory data. Therefore, these anti-VEGF agents could be prescribed safely to patients with AMD.
Combined retinal massage and autologous blood covering for persistent macular holes after vitrectomy in high myopia
Authors: Yao Xiaonan , Chen Dong , Lin Ping , Cui Wei , Chen Nan 
Published: August 2024

Abstract

Purpose:
To evaluate the efficacy of retinal massage combined with autologous blood covering in the treatment of persistent macular holes following vitrectomy in eyes with high myopia.

Settings and Design:
Retrospective, consecutive case series in a tertiary eye center.

Methods:
A total of 12 highly myopic eyes with persistent macular holes after vitrectomy and internal limiting membrane peeling received combined retinal massage, air/fluid exchange, autologous blood covering, and gas/silicone oil tamponade. Best-corrected visual acuity, axial length, and optical coherence tomographic images before and after the treatment were compared.

Results:
The mean hole diameter before this intervention was 931.58 ± 244.58 Symbolm (range, 508–1270), and the axial length was 30.39 ± 2.13 mm (range, 27.08–34.64). During the 6-month follow-up period, hole closure was achieved in eight eyes (66.67%). The mean best-corrected visual acuity improved significantly from 1.40 ± 0.50 logarithm of the minimum angle of resolution (logMAR) at baseline to 1.10 ± 0.30 logMAR (P < 0.05). No complications were observed.

Conclusions:
Combined retinal massage and autologous blood covering, which is easy to manipulate, can promote the closure of persistent macular holes after vitrectomy and improve vision in high myopia with an axial length less than 29 mm.
Comparison of C-MAC® conventional blade, D-Blade™, and Macintosh laryngoscopes for endotracheal intubation in patients with simulated immobilization using manual in-line stabilization: A randomized trial
Authors: Dabas M , Gupta M , Mohanan S , Kaushik P , Lall R 
Published: August 2024

ABSTRACT

Background:
A difficult airway is anticipated with cervical spine injuries (CSIs) as immobilization techniques such as manual in-line stabilization (MILS) are used, which distort the oro-pharyngeal-laryngeal axis. Video laryngoscopes (VLs) make difficult airway management easy, as they do not require axis alignment. The present study aimed to compare the total time taken by Macintosh laryngoscope (ML), conventional blade, and D-blade™ of C-MAC® VL in simulated CSI scenarios using MILS.

Methods:
Ninety patients were randomly allocated into three groups: Group M (ML), Group C (conventional blade of C-MAC®), and Group D (D-blade™ of C-MAC®) with MILS applied before intubation. Primary outcome was the total time taken for successful intubation, while secondary outcomes were to assess Cormack–Lehane (CL) grade, number of attempts, hemodynamic response, and associated complications.

Results:
Total time for intubation in Group C was 23.40 ± 7.06 sec compared to 35.27 ± 6.53 and 47.27 ± 2.53 sec in groups D and M, respectively (P < 0.001). CL-grade I was observed in 15/30 (50%) in Group M, 25/30 (83.3%) in Group C, and 29/30 (96.7%) in Group D. Group M reported 7/30 (23.3%) failed intubations, while none were observed in other groups. Hemodynamic parameters were significantly higher at 3 and 5 min in Group M. Postoperative sore throat was recorded in 12/30 (40%) in Group M compared to 3/30 (10%) in groups C and D each (P value 0.037).

Conclusion:
C-MAC® VL requires less time for intubation, provides better glottic view, and has higher success, with better attenuation of hemodynamic response and fewer complications compared to ML.
Association Between Physical Activity and Risk of Developing Type 2 Diabetes Among Older Adults in Nigeria: A Cross-Sectional Study
Authors: Ishaku Cornelius M. , Umar Saidu , Awotidebe Adedapo W. , Fidelis Francis , Umeonwuka Chuka I. , Maduagwu Stanley M. , Jasper Unyime S. , Oyeyemi Adewale L. 
Published: August 2024

Abstract

Context:
Type 2 diabetes is a growing public health problem worldwide, causing a high number of premature mortalities, especially among older adults.

Aim:
To understand the association between moderate-to-vigorous physical activity (MVPA) and the risk of developing type 2 diabetes among older adults.

Materials and Methods:
A multistage probability sampling technique was used to recruit 400 older adults (age =68.8 ± 6.5 years; male =68.8%) from their households in Maiduguri. Weekly minutes of MVPA were evaluated using the Hausa International Physical Activity Questionnaire-Short form, and the risk of developing type 2 diabetes was measured using the validated Finnish Diabetes Risk Score Questionnaire. Adjusted linear regression analysis explores associations between MVPA and the risk of developing type 2 diabetes.

Results:
It was found that 18.4% of the participants were obese, and 14.5% had a high and very high risk of developing type 2 diabetes. After adjusting for confounding variables (age, gender, BMI, and level of education), MVPA was associated with the risk of developing type 2 diabetes (β = −1.75, P = 0.01). There was significant interaction with gender, with protective effect found only in male older adults (β = −2.59, P = 0.01) and not among female Older adults (β =0.54, P = 0.61).

Conclusions:
Our data suggest that higher levels of MVPA are associated with a lower risk of developing future type 2 diabetes in a population of older adults in Nigeria, especially among men. A future longitudinal study, with a diverse large sample size and more objective measures, is needed to further determine the generalization of the findings observed.