bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reading Uncle Bumba and the Rumba: The Comedian Harmonists and Transnational Youth Culture at the End of the Weimar Republic
Authors: Pennington Stephan 
Published: October 2015

ABSTRACTThis article presents an analytical and cultural reading of the 1932 song ‘Der Onkel Bumba aus Kalumba tanzt nur Rumba’ by the German vocal group the Comedian Harmonists. It incorporates Erving Goffman's stigma theory to propose an alternative interpretation of performances of commercial rumba and jazz by members of a Weimar cosmopolitan youth culture that pushes beyond paradigms of appropriation and exoticism. The author argues that songs seemingly exoticizing an Other could rather serve as a means of articulating concerns of an Othered Self in the context of the rise of National Socialism. The article contrasts a close reading of the Comedian Harmonists’ performance of the song with performances by Leo Monosson and the Melody Gents and incorporates the contrasting experiences of the lyricist Fritz Rotter with those of the Comedian Harmonists to show how ‘Der Onkel Bumba’ presented jazz/rumba as an indicator for both utopian idealism and looming dystopian horror.
Cytomegalovirus Genotype Distribution Among Congenitally and Postnatally Infected Patients: Association of Particular Glycoprotein (g)B and gN Types With Symptomatic Disease
Authors: Brañas Patricia , Blázquez-Gamero Daniel , Galindo Alberto , Prieto Columbiana , Olabarrieta Iciar , Cuadrado Irene , Folgueira Lola 
Published: October 2015

AbstractBackground.  Human cytomegalovirus is a leading cause of congenital infection, and there are limited data on prognosis markers in disease development. We aimed to study 3 virology targets (glycoprotein [g]B, gN, and UL144) to assess their correlation with congenital infection and various organ system involvement.Methods.  Forty-eight congenital cases and 58 postnatally infected children were included (2003–2014). Genotyping for the 3 targets and distribution among the cohorts were investigated, and the relationship between the gB, gN, and UL144 types with clinical manifestations in congenital infection was also studied.Results.  All of the genotypes were similarly represented among cohorts, and the most prevalent were the UL144B, gB1, and gN1 genotypes. The gB2 genotype was associated with abnormal image findings by ultrasound and/or magnetic resonance in congenital infection (odds ratio [OR], 6.2; 95% confidence interval [CI], 1.1–34.3; P = .036); the gN1 genotype was associated with an elevated risk of developing neurological disorders (OR, 7.0; 95% CI, 1.1–45.9; P = .043). Both gN1 and gB2 were independent factors for symptomatic infection. Statistical analyses showed no association between any UL144 genotype and disease severity.Conclusions.  All of the genotypes can be involved in congenital infection, although the gB2 and gN1 genotypes might be associated with a more serious illness.
The Effect of Clevidipine on Cerebral Blood Flow Velocity and Carbon Dioxide Reactivity in Human Volunteers
Authors: Lemkuil Brian P. , Gierl Brian T. , Patel Piyush M. , Pearn Matthew L. , Nguyen Liem C. , Minokadeh Anushirvan , Drummond John C. 
Published: October 2015

Background:
Clevidipine is a short acting, esterase metabolized, calcium channel antagonist administered as a continuous infusion for control of hypertension. Its profile allows for rapid titration and may be uniquely suited to achieving tight hemodynamic targets in neurosurgical and neurocritical care patients. The present study was designed to investigate the effect of clevidipine infusion on cerebral blood flow and cerebral CO2 responsiveness as measured by cerebral blood flow velocity (CBFV) using transcranial Doppler.

Materials and Methods:
CBFV was continuously recorded in 5 healthy subjects during the following conditions: baseline 1 (BL1); baseline with hyperventilation (HV1); baseline 2 (BL2); clevidipine infusion to achieve 15% mean arterial pressure (MAP) reduction (C15); clevidipine infusion to achieve 30% MAP reduction (C30); clevidipine infusion to 30% MAP reduction with hyperventilation (HV2).

Results:
The mean CBFV during intermediate (C15) or maximum (C30) dose clevidipine infusion was unchanged compared with baseline (BL2) (F
2,8=0.66; P=0.54). Cerebral CO2 reactivity, expressed as %∆CBFV/∆mm Hg CO2, was not significantly different in the presence of maximal-dose clevidipine (HV2) as compared with baseline (HV1) (1.6±0.4 vs. 1.6±0.3%∆CBFV/∆mm Hg CO2, P=0.73).

Conclusions:
Clevidipine infusion did not significantly increase CBFV nor was cerebral CO2 reactivity reduced during maximal-dose clevidipine infusion. Further systematic investigation of clevidipine in patients with central nervous system pathology seems justified.
The Potential Prognostic Value of Connexin 43 Expression in Head and Neck Squamous Cell Carcinomas
Authors: Dános Kornél , Brauswetter Diána , Birtalan Ede , Pató Anna , Bencsik Gabriella , Krenács Tibor , Peták István , Tamás László 
Published: October 2015

Gap juctions are transmembrane communication channels known to be involved in the control of cell proliferation by mediating the exchange of ions and small molecules between cells. Gap junctions are composed of connexon hemichannels made up of 6 connexin proteins, which abnormal expression and functions have been linked to tumor progression and poorer prognosis. Here, we studied the prognostic impact of the most prevalent connexin isotype, connexin 43 (Cx43) in head and neck squamous cell carcinomas (HNSCC). Tissue microarrays made from tumor samples of 90 HNSCC patients were immunostained for Cx43 and cell cycle regulation–related biomarkers including p53, Ki67, p16ink4, aurora A, geminin, and p21waf1 proteins. Scoring and histopathologic evaluation were performed in digital slides. A 4-tier scoring distinguishing the percentage of positively stained tumor cells was used including score 1: <5%, score 2: 6% to 20%, score 3: 21% to 60%, and score 4: >60%. For statistics, Kaplan-Meier curves with log-rank tests, Cox-regression, and Pearson χ2/Fisher exact tests were used.
A significant positive correlation was found between Cx43 expression and disease-specific survival of patients (P=0.004). The rate of p21waf1 protein–positive tumor cells also proved to be a significant positive prognostic marker (P=0.014). Cx43 levels also showed a significant positive correlation with p53 expression (P=0.036). However, there was no statistical association between Cx43 levels and the rest of the markers tested neither with T, N, or M stage.
In conclusion, our data suggest that reduced Cx43 expression and low p21waf1 protein levels may have a significant negative impact on HNSCC prognosis.
A paediatric case of lymphadenitis by toxigenic Corynebacterium ulcerans
Authors: Terada Tomomasa , Suga Kenichi , Yamamoto Akihiko , Ono Akemi , Inoue Miki , Kawahito Masami , Mori Kazuhiro 
Published: October 2015

Introduction:

Corynebacterium ulcerans, a potentially toxigenic zoonotic agent, may produce diphtheria toxin and causes varied types of infections in humans. Cases of infection due to toxigenic C. ulcerans infection have been increasingly reported.

Case presentation:
A 6-year-old Japanese girl who had been vaccinated using diphtheria toxoid presented with fever and swelling in the left neck. Ultrasonography showed cervical lymphadenitis with cellulitis. C. ulcerans was isolated from the drainage specimen. The infection was cured with erythromycin administration. Her anti-diphtheria toxoid antibody level was at an adequate level for diphtheria prevention on admission and was significantly increased 3 weeks later. Zoonotic infection was considered likely, because a family cat had shown rhinitis and skin ulcers prior to symptom onset in the child.

Conclusion:
In addition to the number of reported cases of infection in adults, C. ulcerans infection in previously vaccinated children should also be a subject of concern in Japan.
Molecular Mechanisms for the Biological Storage of Renewable Energy
Authors: Barstow Buz 
Published: October 2015

AbstractRecent and ongoing discoveries in the field of extracellular electron transport offer the potential to electrically power highly flexible, carbon-fixing microbial metabolisms and generate a rich variety of chemicals and fuels. This process, electrosynthesis, creates the opportunity to use biology for the low cost storage of renewable electricity and the synthesis of fuels that produce no net carbon dioxide. This article highlights recent discoveries on the molecular machinery underpinning electrosynthesis and reviews recent work on the energy conversion efficiency of photosynthesis to begin to establish a framework to quantify the overall energy storage and conversion efficiency of electrosynthesis.
Results of an attempt to reproduce the STAP phenomenon
Authors: Aizawa Shinichi 
Published: October 2015

AbstractThis reports the results of an attempt by Haruko Obokata to replicate the phenomenon of stimulus-triggered acquisition of pluripotency (STAP), which was first reported in a pair of papers authored by Obokata and colleagues in 2014. The most conclusive evidence for the pluripotency of so-called STAP cells was their purported ability to contribute to chimera formation. In the follow-up trial presented here, putative STAP cells prepared by Obokata were injected into 1154 embryos, of which 671 were recovered. However, the injected cells made no significant contribution in any tissue in any of the embryos developed.
“Teleswallowing”: a case study of remote swallowing assessment
Authors: Bidmead Elaine , Reid Tilly , Marshall Alison , Southern Veronica 
Published: October 2015

Purpose
– Telemedicine has enabled speech and language therapists (SLTs) to remotely assess swallowing difficulties (dysphagia) experienced by nursing home residents. The new technique, “teleswallowing”, was designed by the Speech and Language Therapy Service at Blackpool Teaching Hospitals NHS Foundation Trust. It allows prompt assessment, avoiding potential risks of aspiration pneumonia, malnutrition, poor rehabilitation, increased hospital stays and reduced quality of life (Hinchey et al., 2005; Langmore et al., 1998). The purpose of this paper is to report on a second pilot of teleswallowing and the concomitant adoption study.

Design/methodology/approach
– The adoption study employed qualitative methods, including consultations with senior managers, semi-structured interviews with nursing home matrons/managers and nurses, two focus groups and semi-structured interviews with SLTs. The project clinical lead kept an activity log, which was used to estimate resource savings.

Findings
– Over a three-month period, six SLTs and 17 patients in five nursing homes participated in teleswallowing assessments. Teleswallowing benefited both patients and participating nursing homes. Better use of therapist time and cost savings were demonstrated and evidence showed that the service could be successfully scaled up. Despite this, a number of barriers to service transformation were identified.

Originality/value
– This is the first implementation of teleswallowing in the UK, but it has been used in Australia (Ward et al., 2012). The approach to engaging stakeholders to understand and address barriers to adoption is novel. The value lies in the lessons learned for future innovations.
Telemedicine in care homes in Airedale, Wharfedale and Craven
Authors: Hex Nick , Tuggey Justin , Wright Dianne , Malin Rebecca 
Published: October 2015

Purpose
– The purpose of this paper is to observe and analyse the effects of the use of telemedicine in care homes on the use of acute hospital resources.

Design/methodology/approach
– The study was an uncontrolled retrospective observational review of data on emergency hospital admissions and Emergency Department (ED) visits for care home residents in Airedale, Wharfedale and Craven. Acute hospital activity for residents was observed before and after the installation of telemedicine in 27 care homes. Data from a further 21 care homes that did not use telemedicine were used as a control group, using the median date of telemedicine installation for the “before and after” period. Patient outcomes were not considered.

Findings
– Care homes with telemedicine showed a 39 per cent reduction in the costs of emergency admissions and a 45 per cent reduction in ED attendances after telemedicine installation. In the control group reductions were 31 and 31 per cent, respectively. The incremental difference in costs between the two groups of care homes was almost £1.2 million. The cost of telemedicine to care commissioners was £177,000, giving a return on investment over a 20-month period of £6.74 per £1 spent.

Research limitations/implications
– The results should be interpreted carefully. There is inherent bias as telemedicine was deployed in care homes with the highest use of acute hospital resources and there were some methodological limitations due to poor data. Nevertheless, controlling the data as much as possible and adopting a cautious approach to interpretation, it can be concluded that the use of telemedicine in these care homes was cost-effective.

Originality/value
– There are very few telemedicine studies focused on care homes.
The economics of health service transformation
Authors: Rachev Boris T 
Published: October 2015

Purpose
– This is a report on a recent development of an innovative coordinated care solution named the Care Coordination Centre (CCC), which targets coordinated care arrangements for a populations expected to benefit the most. The purpose of this paper is to identify the patients who might comprise this group, and to assess the best ways to meet their health, community, and social care needs before and after introducing the coordinated care solution across care settings.

Design/methodology/approach
– This is a summary of the author’s experience in the design and development of a care coordination business model for US providers and UK Clinical Commissioning Groups (CCGs) using coordinated care not only as a cost-cutting tool, but as a mechanism for creating a flexible and responsive patient-centered care. The author makes an assessment of the economic benefits of coordinated care resulting from: the shift to less costly interventions; reduction in readmissions; reduced unplanned admissions; increased time allocation efficiency of healthcare staff; and the overall reduction in per-patient costs.

Findings
– The health and social care systems in the USA and the UK are facing the biggest challenges in their history. Payers, providers, governments, and communities need to work to build better coordination and integration mechanisms to manage the increasing demand on health and social care in a period of stagnant health and social care budgets. New innovative models of coordinated care have been developed in both countries, at the local economy level, as the health service systems are undergoing crucial transformation from a supply to a demand-based model. In the UK, the Trafford CCG has commissioned a new CCC, responsible for the delivery of high-quality coordinated care. The CCC is designed to function at clinical, service, and community levels across multiple providers to cover, among other tasks, chronic condition patient case management, risk stratification of preventative, elective, and unscheduled care for the whole region.

Originality/value
– Insights from the work with Trafford CCG would be of considerable methodological and practical interest to researchers, policy makers, commissioners, healthcare professionals, and innovators.
Saving lives through effective patient engagement around NHS health checks
Authors: Alpsten Tobias 
Published: October 2015

Purpose
– Putting behavioural insights theory into practice a trial in Southwark using iPLATO Hub to communicate with over 13,000 patients concluded that the right combination of text messaging and letter content increased uptake of NHS Health Checks by 65 per cent. This iPLATO case study, based on a randomised controlled trial with the Department of Health, Public Health England and Southwark Council, reported in July 2015. The purpose of this paper is to spread best practice and help other parts of the country transform uptake to NHS Health Checks.

Design/methodology/approach
– This research – led by the Department of Health and Southwark Council – was designed to test the impact of certain forms of communication informed by insights from behavioural science. These insights involved small, pragmatic and very low cost or free changes to the invitation process, for example, how messages are framed and the language used. These changes are designed to fit within existing practice, which means they can easily be scaled up across all CCGs.

Findings
– Results from the trial also indicate that a combination of the deadline commitment letter and just a reminder text message (no primer message) was nearly as effective as two texts, while the new letters on their own (without any text messages) increased uptake to 21 per cent. This suggests that clear and concise text messages from the iPLATO Hub delivered the major impact on uptake.

Originality/value
– iPLATO is working with the research group to expand the research and improve on the reported findings while helping to spread best practice across the NHS.
Lean Six Sigma project selection using hybrid approach based on fuzzy DEMATEL–ANP–TOPSIS
Authors: Vinodh S , Swarnakar Vikas 
Published: October 2015

Purpose
– The purpose of this paper is to select the optimal Lean Six Sigma (LSS) project using hybrid fuzzy-based Multi-Criteria Decision-Making (MCDM) approach for an automotive component manufacturing organization.

Design/methodology/approach
– The LSS project selection has been formulated as the MCDM problem. Hybrid MCDM method based on Decision-Making Trial and Evaluation Laboratory Model (DEMATEL), Analytical Network Process (ANP) and Technique for Order Preference by Similarity to Ideal Solution (TOPSIS) has been used to select the optimal LSS project. The methodology enabled the practitioners to systematically prioritize LSS projects.

Findings
– The finding of this study is that, out of five LSS projects, project P3 is the best LSS project. P3 is the optimal LSS project with reduced failure risk, and efforts are being taken to implement the selected project.

Research limitations/implications
– The problem formulation and methodology has been tested for a single study. In future, more number of studies could be conducted using the hybrid approach. This method is presently applied for an automotive component manufacturing organization; in future, the approach could be applied in different industrial sectors for improving its effectiveness.

Practical implications
– The case study has been conducted in a real-time industrial problem. The practitioners expressed the usefulness of the methodology for prioritizing LSS projects Hence, the inferences derived are found to possess practical relevance.

Originality/value
– The original contribution of the study is the selection of optimal LSS project using hybrid MCDM technique.
Materiality and external assurance in corporate sustainability reporting
Authors: Jones Peter , Comfort Daphne , Hillier David 
Published: October 2015

Purpose– The purpose of this paper is to provide a preliminary examination of the extent to which the UK’s leading house builders are embracing the concept of materiality and commissioning independent external assurance as part of their sustainability reporting processes and to offer some wider reflections on materiality and external assurance in sustainability reporting.Design/methodology/approach– The paper begins with a review of the characteristics of materiality and external assurance and a brief outline of house building in the UK and of the sustainability challenges the industry faces. The information on which the paper is based is drawn for the top twenty UK house builders’ corporate Websites.Findings– The paper reveals that only a minority of the UK’s top 20 house builders had embraced materiality or commissioned some form of independent external assurance or verification as an integral part of their sustainability reporting processes. In many ways this reduces the reliability and credibility of the house builders’ sustainability reports. Looking to the future growing stakeholder pressure may force the UK’s house builders to embrace materiality and commission external assurance as systematic and integral elements in the sustainability reporting process.Originality/value– The paper provides an accessible review of the current status of materiality and external assurance in the UK house builders’ sustainability reporting process, and as such it will interest professionals, practitioners, academics and students interested in sustainability in the construction industry.
Neoclassical economics and new institutional economics
Authors: Agboola Alirat Olayinka 
Published: October 2015

Purpose– The purpose of this paper is to examine the provisions of both the neoclassical economics and new institutional economics theses and assesses the implications of their methodologies for property market analysis.Design/methodology/approach– This research is based on secondary literature review and desk-based study.Findings– It is argued that new institutional economics, grounded on firmer foundations of human behaviour, offers an analytical approach to the study of the property market which emphasizes the institutionally contingent nature of real estate exchange, thus placing real estate within its socio-economic context.Originality/value– In-depth examination and juxtaposition of the provisions, assumptions, philosophical orientations and limitations of these main traditions of economic thought towards the achievement of a representative study of the workings of the property market.
From impact to advocacy: working together toward public library sustainability
Authors: Cottrill Julia , Letelier Fernando , Blanco Pablo Andrade , García Henry , Chiranov Marcel , Tkachuk Yuliya , Liubyva Tetiana , Crocker Rachel , Vanderwerff Matthew , Cistoviene Giedre , Krauls-Ward Ineta , Stratilatovas Eugenijus , Mount Dan , Kurutyte Agniete , . Triyono 
Published: October 2015

Purpose
– The purpose of this paper is to outline the Bill
&
Melinda Gates Foundation’s Global Libraries (GLs) initiative approach to advocacy and how it informs, guides, and integrates impact data to support sustainability of GL program results.

Design/methodology/approach
– The paper defines advocacy in the context of GL, and explores the GL grant planning process, tools, and collaboration between advocacy and impact specialists. Results are demonstrated through grantee examples that illustrate a variety of approaches to library advocacy using impact data at local, country, and regional levels.

Findings
– The paper demonstrates the importance of identifying community needs, designing impact measures to demonstrate how libraries help to address those needs, and the variety of ways impact evidence can be used to effectively advocacy for public libraries. This basic formula can be applied to advocacy efforts ranging from a broad national policy to a small incremental change in perceptions of libraries by local decision makers.

Originality/value
– This paper reinforces the essential link between library impact measurement data and successful advocacy.