bluuebunny/crossref_metadata_2025_split huggingface dataset:
Identification of the energy parameters of an electrohydroimpulse plant for the production of valuable components from organic raw materials
Authors: Kartbayeva Gulnaz , Duisenbayeva Moldir , Nussupbekov Bekbolat , Mussenova Elmira , Smagulov Zhanaidar , Kurmanaliev Alikhan 
Published: July 2024

The paper presents the results of experimental studies on the developed bone degreasing stand. The object of the study is the production of valuable components from organic raw materials.
Fractions of cattle crushed to the size of 2.5 mm, 5.2 mm and 10.5 mm were used to identify the effective mode of operation of an electrohydroimpulse installation.
Physical and chemical methods of fat extraction are currently not relevant from the point of view of economy, due to environmental damage and labor intensity. In this regard, new effective methods of extracting fat from bone mass are needed. Therefore, the proposed method of extracting fat by spark discharge is an actual and alternative method for today.
During the study, an acceptable temperature regime for fat production was obtained. Next, a laboratory stand was assembled, with which you can degrease the bone mass without changing the properties of fat.
Experimental studies show that with an increase in the capacity of the capacitor bank in energy storage devices and the length of the discharge gap, the bone degreasing process becomes more efficient. During the study, it was found that at a liquid temperature of 38 °C and a pulse voltage of 25 kV on a switching device of an electrohydroimpulse installation, the degree of fat extraction increases without destroying the morphological structure of bone mass.
Using the hexane extraction reaction, we determined the efficiency of fat extraction at a temperature of 38 °C, at which the fat mass from the bones is effectively broken down, and using the UV-1800 spectrophotometer, we determined the amount of protein in the bones before and after treatment.
The study also showed that with a capacitor bank capacity of 0.5 uF, crushed to a fraction of 10.5 mm of pelvic bone, the separated fat is 18.7 %, and with constant grinding of the capacitor bank to a fraction of 2.5 mm – 19.4 %
Establishing patterns in the structure formation of polymer nanocomposites based on polyamide 6 during their crystallization processes
Authors: Fialko Nataliia , Meranova Nataliia , Sherenkovskii Julii , Navrodska Raisa , Babak Vitalii , Korzhyk Volodymyr , Lazarenko Maxim , Koseva Neli , Konoreva Oksana , Dinzhos Roman 
Published: July 2024

This paper reports experimental and computational studies on patterns in the structure formation of polymer nanocomposites when different types of fillers are used. The study was conducted for nanocomposites based on polyamide 6 filled with carbon nanotubes or silicon dioxide nanoparticles. In the course of research, the mass fraction of the filler varied from 0.2 % to 4.0 %, and the cooling rate of the melt composite varied from 0.5 K/min up to 20 K/min.
Data on experimental and theoretical studies into the mechanisms of structure formation of composites according to the method, which includes two stages, are given. According to the first stage, crystallization exotherms of nanocomposites were experimentally obtained when they are cooled from the melt at a given constant rate. The dependence of various characteristics of the crystallization process on the mass fraction of the filler and the cooling rate of the composite was established.
At the second stage, based on the analysis of the obtained crystallization exotherms, theoretical studies were performed to determine the mechanisms of structure formation of nanocomposites at different stages of crystallization. For the initial stage, according to the nucleation equation, the presence of two mechanisms of structure formation – planar and volumetric – has been shown.
Within the framework of the Kolmogorov-Avrami equation, the mechanisms of structure formation at the next stage of crystallization were established, which corresponds to the formation of ordered structures in the material within the volume of the polymer composite as a whole. The research was carried out assuming the existence of a mechanism of crystallization of the polymer matrix itself, which is realized on fluctuations in the density of the polymer, and a mechanism of crystallization, the centers of which are filler particles.
The use of the proposed nanocomposites is promising for the manufacture of parts of energy equipment, electronic equipment, elements of chemical, processing, defense industry installations, etc.
Development of predictive model for determination of paraffin deposition in Kazakh crude oil
Authors: Sarsenova Adel , Ismailova Jamilyam , Ismailov Abdulakhat , Delikesheva Dinara , Kaidar Aigerim 
Published: July 2024

Kazakhstan's crude oil contains significant amounts of heavy hydrocarbons that solidify as wax at lower temperatures, leading to reduced flow rates and potential blockages in pipelines. Paraffin, a substantial component of crude oil, crystallizes below its pour point, posing challenges for maintaining efficient crude oil transportation. Addressing wax deposition is essential for optimizing oil flow and meeting global energy demand. This article presents an innovative method for forecasting paraffin deposition in Kazakh crude oil, using its chemical composition and thermobaric conditions. The methodology encompassed data analysis, ASTM-standard laboratory tests, and computations employing modified equations for fusion properties calculation. Outcomes comprise computed temperatures, enthalpy, and heat capacity related to melting, along with revised correlations for melting and pour points specific to Kazakh crude oils. The melting point correlation was modified to fit the properties of Kazakh crude oils, resulting in standard deviation of 0.55 %. Computed pour points for hydrocarbons improved by 17 % respectively. As a result of the research a novel software tool was developed and evaluated, highlighting the project’s contribution in providing an adjusted thermodynamic model for paraffin deposition forecasting. Comparisons between the developed software, PVTSim, and field data showed the wax appearance temperature (WAT) predictions closely aligned, with 0.74 % of error. This numerical tool shows potential in predicting wax deposition, thus aiding in the planning of oil production and refining processes in Kazakhstan. The importance of this work extends to its potential economic impact on companies and the nation, as well as its environmental benefits by facilitating eco-friendly planning of oil production facilities. Future research could expand on these findings to further enhance predictive models of paraffin precipitation across diverse conditions
Novel eco-friendly spectrophotometric determination of lercanidipine hydrochloride in tablets using methyl red
Authors: Kryskiw Liubomyr , Horyn Mariana , Kucher Tetyana , Zarivna Nadiya , Poliak Olha , Logoyda Liliya 
Published: July 2024

The aim of the work was to develop a simple, eco-friendly, quick, affordable and alternative spectrophotometric procedure that uses the azodye methyl red (MR) for the determination of lercanidipine in its dosage form considering the “green” chemistry principles.
Materials and methods. Analytical equipment: Shimadzu UV-1800 double beam UV-visible spectrophotometer (Japan) with included UV-Probe 2.70 software, RAD WAG AS 200/C precise analytical balance (Poland), Elmasonic EASY 40H ultrasonic bath.
Lercanidipine hydrochloride (purity 99 %) was purchased from Jiyan Chemicals (India). Lercanidipine tablets 10 mg and 20 mg were used in our experiments.
Results and discussion. To determine the amount of lercanidipine in tablets, a spectrophotometric method has been developed. To select the best dye for the method development, we tested a variety of dyes, including MR, bromocresol purple, bromophenol blue, cresol red, bromocresol green and bromothymol blue. We selected MR as the reagent based on the experimental studies' outcomes, and the solvent was an acetonitrile and ethanol mixture with a ratio of 95 to 5. The optimal parameters were determined for the quantitation of lercanidipine in tablets utilizing MR with 5×10-5 mol/L of dye concentration, 0.5 ml of MR solution, at a temperature of 25 °C without heating; detection wavelength was 498 nm and reaction time of 5 min. By using the molar ratios (saturation) method and Job's (continuous variations) approach, the stoichiometric coefficients of reacting components involving lercanidipine and dye were established to be 1:1. The proposed spectrophotometric procedure was linear within the concentration ranging from 6.48 – 32.41 μg/mL. Using the least squares method, a regression equation was generated: y = 0.0208x – 0.0318. The correlation coefficient was higher than 0.999, indicating that the analytical procedures' linearity is acceptable; the limit of detection and limit of quantitation were 1.19 μg/mL and 3.62 μg/mL, respectively. The robustness, accuracy and precision of the study results fell within acceptable limits. The proposed method was successfully applied to determine the content of lercanidipine in its tablet dosage forms. The analysis of the method's "greenness" using AGREE and GAPI tools yielded excellent results.
Conclusions. The method that has been developed can serve as an alternative approach for the routine control of lercanidipine content in its tablets
On Bootstrap Algorithms in Survey Sampling
Authors: Żądło Tomasz 
Published: July 2024

Objective: The aim of this paper is to present bootstrap algorithms for measuring the accuracy of estimation and prediction in design-based and model-based approaches in survey sampling and small area estimation. Three proposals of prediction-mean squared error estimators are also examined.
Research Design & Methods: Various bootstrap procedures are shown and used to estimate the design- and prediction-mean squared errors based on real data. Computations are supported by two R packages.
Findings: Three prediction-mean squared error estimators are proposed.
Implications / Recommendations: The bootstrap algorithms used in the design-based approach give similar results for the considered data for the variance estimates of the considered estimator, implying that the speed of the algorithms may be important for practitioners in cases of similar properties. The proposed estimators of the prediction mean squared error produce higher estimates than other estimators in the model-based approach, indicating a positive bias that can be interpreted as a pessimistic accuracy estimate.
Contribution: All the presented bootstrap algorithms are easily applicable using two R packages available at R CRAN and GitHub. Three double bootstrap prediction-MSE estimators are proposed and analysed in the real-data application.
Potential Effects of Some Factors on Psoriasis Course in Children
Authors: Gubanova Svetlana G. , Ambarchyan Eduard T. , Namazova-Baranova Leyla S. , Vishneva Elena A. , Zelenkova Irina V. , Gankovskiy Viktor A. , Aleshenko Nataliya L. , Kaytukova Elena V. , Kuzminova Anastasiya D. , Ivanchikov Vladislav V. 
Published: July 2024

Psoriasis is the second most common skin disease after atopic dermatitis in childhood. There are factors affecting both the manifestation and aggravation of this inflammatory skin process. The leading role in the psoriasis pathogenesis is currently associated with key cytokines. However, infectious diseases could be the triggers for psoriasis.Nowadays, the approach to psoriasis management in children has been revised due to emerging of new knowledge about the clinical manifestations and the role of numerous comorbid conditions in psoriasis course. Risk factors assessment, as well as evaluation of potential comorbidities signs and symptoms, is crucial part in patient management to create a prognostic model of the disease progression and the aggravation development (with underlying associated inflammatory processes included).
Bacterial infections in hospitalized cancer patients. The role of drug-resistant pathogens
Authors: Petukhova I. N. , Grigoryevskaya Z. V. , Bagirova N. S. , Aginova V. V. 
Published: July 2024

Aim. To present data on the structure of bacterial pathogens causing infectionsin cancer patients atthe N.N. Blokhin National Research Center of Oncology and analyze them in comparison with data of domestic and foreign literary sources.Materials and methods. The data of 11,853 microorganisms isolated from patients hospitalized in the N.N. Blokhin National Research Center of Oncology in 2023 were analyzed.Results. Bacteria accounted for 90.0 % of all isolated microorganisms and only 10.0 % were fungal pathogens. Despite the fact that gram-negative pathogens have given way to gram-positive pathogens in absolute numbers, gram-negative microorganisms (60.7 %) still prevail in “clinically significant” biomaterials (blood, spinal fluid, urine, wound discharge, BAL, etc.), primarily Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Acinetobacter baumannii and others. With the exception of Escherichia coli, a high percentage of carbapenem-resistant strains is noted for other pathogens: Klebsiella pneumoniae – 34 %, Pseudomonas aeruginosa – 50 %, Acinetobacter baumannii – 69 %. Real-time polymerase chain reaction revealed the leading carbapenemases: in Klebsiella pneumoniae strains – KPC or OXA-48 carbapenemases were detected in 55 % of cases, and NDM metallo-β-lactamasesin 45 %; in Pseudomonas aeruginosa strains – VIM metalloβ-lactamases were registered in 29 % of cases. Among gram-positive microorganisms, the most problematic is vancomycinresistant Enterococcus faecium. It accounts for 45 % of all E. faecium strains.Conclusion. Along with modern diagnostics and infection control measures, knowledge of the leading microbiota in a particular clinic will prevent the spread of infection and provide timely medical care to patients.
Lung neuroendocrine tumors
Authors: Markarova E. V. , Kogoniya L. M. , Gurevich L. E. , Bondarenko E. V. , Shikina V. E. 
Published: July 2024

Neuroendocrine tumors are a large and heterogeneous group of tumors that develop from neuroendocrine cells. To define this type of tumor, the well-established term “carcinoid” continues to be used in clinical practice for years. In accordance with the characteristics of embryogenesis, three groups of neuroendocrine tumors are distinguished. The source of these tumors are neuroendocrine cells, which are located in almost all organs. The term itself and the concept of “neuroendocrine cell” have historically been repeatedly reassessed. In 1969 A. Pearse, based on the ability of these cells to utilize and decarboxylate amine precursors, introduced the term “APUD system” (aminoprecursor uptake and decarboxylation). Neuroendocrine cells, although they can secrete the same substances as neurons, but, unlike the latter, they participate not in topical, but in paracrine regulation of organs and tissues. They are located in all human organs and are the most important tool for maintaining homeostasis.In recent years, more and more publications have appeared about the frequent localization of neuroendocrine tumors in the lungs, and new approaches to the diagnosis of this pathology. This review presents the diagnostic features and clinical course of pulmonary neuroendocrine tumors.
Optimization of intrauterine interventions in spontaneous abortion
Authors: Salov I. A. , Naumova I. V. , Lomovitskaya M. V. 
Published: July 2024

Introduction. Retained products of conception (RPOC) are detected in 15 % of women after spontaneous or medical abortion. RPOC blind removal from the uterine cavity remains the "gold standard" of surgical treatment, which, however, may be associated with a high risk of certain complications that pose a serious threat to female reproductive function and quality of life. An alternative method for eliminating RPOC proposed by operative hysteroscopy demonstrating the visual control advantages.Aim: to evaluate clinical effectiveness and safety of RPOC removal in incomplete spontaneous abortion using hysteroscopic morcellation.Materials and Methods. The prospective comparative study included 135 women with incomplete spontaneous abortion aged 18 to 40 years, divided into 3 groups: group 1 – 42 patients after RPOC electromechanical vacuum aspiration (EVA); group 2 – 44 patients after RPOC manual vacuum aspiration (MVA); group 3 – 49 patients after RPOC hysteroscopic morcellation (HM). In all patients, the level of total endotoxin was measured, metroaspirate cytokine profile was analyzed, the indicator of endometrial microcirculation was assessed before surgical treatment and on day 1 afterwards, and genital ultrasound examination was performed on day 3–5 post-surgery.Results. In the post-surgical vs. pre-treatment period, the EVA and MVA groups revealed significantly increased levels of total endotoxin and interleukin (IL) IL-1β (p < 0.05). In contrast, these parameters in the HM group changed insignificantly (p > 0.05). In all groups, IL-8 and tumor necrosis factor alpha (TNF-α) levels after surgery were significantly elevated (p = 0.001). In the EVA and MVA groups, levels of anti-inflammatory cytokines IL-4 and IL-10 were markedly decreased (p = 0.001), which did not change in the HM group (p > 0.05). A significantly accelerated microcirculation rate was noted in the EVA and MVA groups while comparing it at pre-surgery level (p = 0.001), but not in the HM group (p = 0.415). Incomplete RPOC removal was reported for 4.5 % MVA patients, all EVA and HM patients had total RPOC elimination. Intraoperative bleeding, uterine perforation were not reported in any examined patient.Conclusion. The early-stage treatment results showed that RPOC removal by the HM is an effective and safe approach. Limited inflammatory response and stable endometrial microcirculation upon using the HM evidence about a minimal impact on the endometrium that lowers probability of postoperative adhesion.
Evaluation of the sperm parameters, oxidative stress, and histopathological effects of vitamin B12 in preventing Helicobacter pylori-induced testicular toxicity: An experimental study
Authors: Mohammadi Forogh , Karimi-Dehkordi Maryam , Pouriayevali Farnaz 
Published: July 2024

Background: Helicobacter pylori (H. pylori) causes sterility by affecting the reproductive system. vitamin B12 improves sperm quantity and function.
Objective: Vitamin B12 protection against H. pylori adverse effects was investigated.
Materials and Methods: 40 C57 male mice (6 wk) were randomly assigned to 4 equal groups (n = 10) including, group 1 (control without any intervention), group 2 (H), 3 (HP), and 4 (HB) received 1×109 colony forming unit (CFU) of H. pylori, 1×109 CFU of H. pylori+phosphate buffered saline, 1×109 CFU of H. pylori+50 μg/kg vitamin B12 intraperitoneally, respectively. In the induction groups, the H. pylori was orogasterically injected 3 times with 1 cc phosphate buffered saline throughout the day. Then testicular metrics, sperm motility, viability, quantity, and shape, plasma levels of malondialdehyde (MDA), superoxide dismutase, glutathione peroxidase, and total antioxidant capacity were measured. Also, testicular-tissue changes were examined using Johnson scores, tubular differentiation index, and spermatogenesis index. Vitamin B12, homocysteine, and testosterone serum levels were examined.
Results: The results showed a significantly lower Johnson score, tubular differentiation index, and spermatogenesis index, and serum level of testosterone and homocysteine as well as a higher MDA level in the H and HP groups than the HB group (p < 0.05). In contrast, the highest superoxide dismutase and glutathione peroxidase enzymes activity and total antioxidant capacity as well as the lowest serum level of MDA were found in the HB group compared to other groups (p < 0.05).
Conclusion: Vitamin B12 increased antioxidant enzyme activity, enhanced sperm parameters, and decreased injury to testicular tissue. It can be used as a potent antioxidant in reducing testicular damage induced by H. pylori.
Key words: Helicobacter pylori, Reproductive medicine, Oxidative stress.
Адаптивна концентрація у вантажній і комерційній роботі в умовах інформатизації технологічних процесів на залізниці України
Authors: Каграманян Артур Олександрович , Ковальов Антон Олександрович , Запара Віктор Мефодійович , Запара Ярослав Вікторович , Шапатіна Ольга Олександрівна 
Published: July 2024

У статті розглянуті особливості проведення адаптивної концентрації у вантажній і комерційній роботі в умовах інформатизації технологічних процесів на залізниці України: введено поняття і сформульовано визначення адаптивної концентрації на залізниці у сфері вантажної і комерційної роботи, розглянуто технологічні аспекти створення і функціонування Пунктів концентрації обробки перевізних документів, сформульовано умову доцільності їх створення, доведено економічну ефективність створення і функціонування таких пунктів на прикладі полігонів регіональної філії «Південна залізниця».
NOMINATA DE AVALIADORES AD HOC E ESTATÍSTICAS 2013
Authors: Carvalho José Ribamar Marques de 
Published: July 2024

O Comitê Editorial da REUNIR: Revista de Administração, Contabilidade e Sustentabilidade UACC/CCJS/UFCG agradece a contribuição voluntária de professores e pesquisadores na avaliação dos artigos que foram submetidos durante o ano de 2013. Reforçamos a importância dessa parceria para o crescimento de nosso periódico.
The clinical profile, management, and outcomes of deliberate self-poisoning in a tertiary care hospital, Pretoria, South Africa
Authors: Chacko Anna John Medayil , Kgole Mmakoma Becky , Mpe Matlawene John 
Published: July 2024

Abstract

Introduction: Deliberate self-poisoning is a major public health problem globally and constitutes a significant proportion of emergency department presentations. The purpose of the study was to determine the clinical profile, management, and outcomes of patients admitted with deliberate self-poisoning to a tertiary public academic center in South Africa.

Methods: A review of the clinical records of medical admissions for deliberate self-poisoning over one year was conducted.

Results: A total of 140 patient records were analysed. The mean age of the group was 25.7 ± 9.4 years of whom 75.6% were females. The majority (96.4%) of patients were unemployed. Pharmaceutical agents were the most common (75%) form of poisoning, taken orally by most (99%). Psycho-social stressors were responsible for deliberate self-poisoning in 49% of the patients. None of the patients had evidence of significant organ dysfunction at admission. Two patients were admitted to the intensive care unit. All patients survived. The median length of stay in the hospital was 5 days (IQR 4–7 days). Treatment consisted of supportive care and, where appropriate, gastric decontamination, administration of antidotes/reversal agents, and referral to psychosocial services.

Conclusion: In this study, a high proportion of the patients were female, unemployed, and single. Psycho-social stressors were the predominant reasons for deliberate self-poisoning and pharmaceutical agents were the main form of poisoning in the majority of cases. Improving the mental health and coping skills of young females could potentially reduce episodes of deliberate self-poisoning among this vulnerable group.