bluuebunny/crossref_metadata_2025_split huggingface dataset:
REVISITAR O CONGRESSO DE MILÃO (1880) E COLOCAR (DEZ/DES) VERDADES EM SUSPENSO
Authors: Rodrigues José Raimundo , Vieira Machado Lucyenne Matos da Costa , Barbosa Olmo Katiuscia Gomes 
Published: August 2024

Inquestionavelmente, a história da educação de surdos foi marcada pelo Congresso Internacional para o Melhoramento da Condição dos Surdos-mudos, ocorrido em Milão (1880), doravante Congresso de Milão, ou mesmo Milão. Para Foucault (2015), é a partir do a priori histórico que a arqueologia se desenha. Por isso propomos aqui um recuo histórico, a fim de encontrar vestígios e fragmentos, marcas, indícios de práticas que são produzidas a partir de narrativas cristalizadas sobre este evento italiano. Para tanto, faz-se necessário olhar para esses discursos, verdades e sentidos produzidos por um ângulo bem diferente daquele que se apresenta imponente. Tendo como metodologia a análise de fontes documentais sobre o evento, o entendemos como um acontecimento bem como um documento-monumento como nos aponta Foucault (2015). Para questionar o que vem sendo propalado sobre este congresso histórico sem o cuidado com a leitura e estudo das fontes primárias, nos ativemos particularmente, às atas oficiais editadas por Pasquale Fornari (1880) bem como os relatórios de Ernest La Rochelle (1880) e Adolphe Franck (1880). Também buscamos estudar o relatório de Edmund Treibel (1880) e o de Arthur Kinsey (1880). Entendemos estes documentos como monumentos e pretendemos servir-nos dos conceitos ferramentas foucaultianos, a saber: arquivo, a priori histórico e verdades.
Polisemi Leksem Qi dalam Bahasa Mandarin
Authors: Taufiq Tania , Kabul Assa Rahmawati 
Published: August 2024

Polisemi adalah suatu leksem yang memiliki sejumlah makna yang masih berkaitan. Leksem qi adalah sebuah leksem berpolisemi dalam bahasa Mandarin. Penelitian ini bertujuan untuk menentukan dan menjelaskan komponen makna yang mengaitkan sejumlah makna yang dimiliki oleh leksem qi. Selain itu, diteliti juga sumbangan makna leksem tersebut dalam kata majemuk qi. Metode penelitian yang digunakan adalah metode kualitatif deskriptif. Data berupa 11 makna leksem qi dan 16 kata majemuk yang mengandung leksem qi dari edisi ke-7 kamus Xiandai Hanyu Cidian (2016). Tabel pengelompokkan konsep makna dan teori Analisis Komponen Makna Nida (1975) digunakan untuk analisis data. Dari hasil penelitian, diketahui bahwa terdapat dua komponen bersama (common component) yang mengaitkan 11 makna pada leksem qi yaitu, [+perbuatan] dan [+perubahan keadaan]. Selain itu, ditemukan bahwa hanya ada 7 makna leksem qi yang menyumbangkan makna pada 16 kata majemuk yang diteliti.
Modeling Gross Enrollment Rate for Higher Education in Central Java Province Using Principal Component Geographically Weighted Regression Approach
Authors: Mohd Syafrizal  , Widyanti Rahayu  , Dania Siregar  
Published: August 2024

Education in a country is a crucial factor in enhancing human resources. The Gross Enrollment Rate for Higher Education is one of the important indicators used by the government to evaluate the development of the education sector, particularly higher education. Social and cultural diversity, as well as geographical influences, result in varying conditions across different regions, leading to each region having its own unique characteristics, known as spatial heterogeneity. Geographically Weighted Regression (GWR) is a method that can address the problem of spatial heterogeneity. Additionally, a common issue encountered in modeling with many independent variables is multicollinearity, which can lead to high variance in regression parameter estimates and invalid conclusions. Principal Component Analysis (PCA) is a dimensionality reduction method that can address multicollinearity. The aim of this research is to model Gross Enrollment Rate in Higher Education in Central Java using GWR, preceded by handling multicollinearity with PCA. Furthermore, this study aims to determine the factors influencing Gross Enrollment Rate in Higher Education in Central Java. The results, using a fixed Gaussian kernel weighting function, indicate that modeling with PCA and GWR performs better than using the Ordinary Least Square (OLS) method alone, yielding an AIC value of 169.43 and a coefficient determination value of 96.2%.
Panel Data Regression Modelling Factors Affecting Participation in Indonesia's National Health Insurance Contribution Assistance Program
Authors: Santi Vera Maya 
Published: August 2024

National Health Insurance (JKN) is a health insurance system that provides health protection to individuals who have paid premiums (non-PBI) or whose premiums are paid by the government (PBI). JKN participation in Indonesia from 2018 to 2021 has consistently increased, particularly for JKN PBI, yet the program has not achieved the target of 100% membership coverage globally or nationally. A deeper understanding of the factors influencing JKN is crucial to enhance the program's effectiveness and formulate targeted policies. This study aims to analyze the factors affecting the participation of JKN PBI annually in Indonesia. The data used in this study cover the period from 2018 to 2021 and involve 34 provinces in Indonesia, thus forming a panel data structure. A panel data regression model is employed to identify the factors influencing JKN PBI participation. The predictor variables analyzed include income levels, access to health facilities, employed population, and education levels. The results indicate that the most suitable model for determining the factors influencing participation in the National Health Insurance PBI with a significance level of is the Random Effect Model (REM). The simultaneous and partial tests show that the variables of the employed population and education levels significantly impact JKN PBI participation. Therefore, the REM is considered appropriate and effective in explaining the factors influencing participation in the JKN PBI program. This study provides insights that can help in formulating more targeted policies to enhance the effectiveness of the JKN program in Indonesia.
Differential interactions determine anisotropies at interfaces of RNA-based biomolecular condensates
Authors: Erkamp Nadia A. , Farag Mina , Qiu Yuanxin , Qian Daoyuan , Sneideris Tomas , Wu Tingting , Welsh Timothy J. , Ausserwӧger Hannes , Krug Tommy J. , Weitz David A. , Lew Matthew , Knowles Tuomas P. J. , Pappu Rohit V. 
Published: August 2024

Abstract

Biomolecular condensates form via macromolecular phase separation, giving rise to coexisting phases delineated by interfaces. Here, we characterize the structures of interfaces formed by phase separation driven by heterotypic interactions in ternary mixtures of two types of RNA molecules and polyethylene glycol. We find that purine-rich RNAs are scaffolds that drive phase separation via strong heterotypic interactions. Conversely, pyrimidine-rich RNA molecules are defined by weaker heterotypic interactions. They function as adsorbents that accumulate at and wet the interfaces of coexisting phases formed by phase separation of scaffolds. Our computations predict that scaffolds and adsorbents have different non-random orientational preferences at interfaces. We tested these predictions using single-molecule super resolution imaging that tracks the motions of fluorogenic probes that are bound to RNA molecules. Motions parallel to the interface were found to be faster than motions perpendicular to the interface. These findings support previous predictions regarding anisotropies of motions at interfaces.
Rare-metal-free broadband near-infrared phosphors
Authors: Xiao Wenge , Zheng Guojun , Lou Chenjie , Zhong Jiyou , Tang Mingxue , Qiu Jianrong 
Published: August 2024

Abstract

Phosphors are the key enabling components for down-converted light emitting diodes (LEDs) which are regarded as the most efficient, cheapest and smallest broadband light sources1,2.Although myriad phosphors have been developed3–8, very few finally come into practical use in consideration of efficiency, stability and price. Unlike visible phosphors, broadband near-infrared (NIR) phosphors rarely achieved high efficiency and high stability9–13, and furthermore, they usually contain high content of rare-metal elements14–18, thus precluding NIR applications of phosphor-converted LEDs (pc-LEDs). Here, we report such a class of broadband NIR phosphors that possesses excellent luminescence properties while is free of rare-metal elements, by revealing weak-field octahedral sites for Cr3+ occupation in MgAl2O4 spinel that is conventionally believed to only offer strong-field octahedral sites. Such weak-field octahedral sites are attributed to the intrinsic cation inversion in the spinel structure, and can be finely engineered by superstoichiometric Al2O3. We further introduce SiO2 to break the inversion symmetry of octahedral sites for boosting the 3d–3d transition probabilities and thus the photoexcitation efficiency. The corresponding pc-LED prototype delivers bright and stable broadband NIR light with an optical power of 180.8 mW and a photoelectric efficiency of 16.0% at the rated current, more than two times those of the commercialized and reported counterparts, meaning a big step forward for broadband light sources.
Depositing Al-Zn-Mg-Cu alloy with different positive electrode/negative electrode ratios of CMT advance process
Authors: Wu Xiangyang , Xu Shanqing , Chen Ji , Wu Chuansong 
Published: August 2024

Abstract

To explore the influence of electrode positive/electrode negative (EP/EN) ratio on CMT advance-based wire arc additive manufacturing (WAAM) process for Al-Zn-Mg-Cu alloy, the behaviors of deposition process, the microstructure and mechanical properties of Al-Zn-Mg-Cu alloy WAAM are studied. The results showed that electrical waveforms and arc/metal transfer were unstable with a low EP/EN ratio, which deteriorated the stability of WAAM. The forming accuracy of deposited samples firstly increased with the EP/EN ratio ranging from 4:16 to 13:7, and then decreased if the EP/EN ratio continued increasing. In the inter-layer region, the samples showed a combination of columnar grains and pony-size equiaxed grains with an EP/EN ratio ranging from 4:16 to 10:10, while the size and quantity of equiaxed grains increased and the columnar grains almost disappeared with a higher EP/EN ratio (≥ 13:7). The enriched alloy elements in the grain boundary were easy to form large-scale precipitated phases, which were harmful to the mechanical properties. The microhardness distribution of all samples had the apparent fluctuation along the building direction due to the existence of the microstructure evolution and pores defect. This study proved that CMT advance process was a practicable and effective way for WAAM of Al-Zn-Mg-Cu alloy with optimal EP/EN ratio.
Accelerated Inference for Thyroid Nodule Recognition in Ultrasound Imaging Using FPGA
Authors: Ma Wei , Wu Xiaoxiao , Zhang Qing , Li Xiang , Wu Xinglong , Wang Jun 
Published: August 2024

Abstract

Thyroid cancer is the most common malignancy in the endocrine system, with a rising incidence worldwide in recent decades. Traditional Central Processing Unit (CPU) and Graphics Processing Unit (GPU) software face limitations in processing speed, efficiency, and power consumption, necessitating more efficient solutions. This study proposes a Field-Programmable Gate Array (FPGA)-accelerated quantized inference method to improve the efficiency and accuracy of thyroid nodule detection. We selected YOLOv4-tiny as the neural network model, incorporating Kmeans + + for optimal anchor box dimensions at the software level and combining 8-bit weight quantization with batch normalization and convolution layer fusion at the hardware level to reduce computational complexity. Additionally, a double buffering mechanism and pipelined design were employed to enhance parallelism and hardware resource utilization. We conducted tests on an internal dataset from a tertiary hospital in China. The experimental results show that our proposed FPGA-accelerated ultrasound thyroid nodule detection system performs excellently in terms of image recognition accuracy, speed, and power consumption. The average accuracy is 81.44% on the Tn3k dataset and 81.20% on the internal test dataset, with each image taking 0.398 seconds to process and consuming 3.119 watts of power. The energy efficiency is 17.6 times that of the Intel Core i5-10200H and 0.98 times that of the GeForce RTX 4090. This study offers a new technological pathway for medical imaging diagnosis, potentially enhancing the speed and accuracy of ultrasound image analysis, thereby improving physician efficiency and diagnostic capabilities.
Effect of insomnia on anxiety about COVID-19 patients :The mediating role of psychological capital
Authors: Heng Chun-Ni , Du Juan , Li Ling , Zhang Na , Jiang Wei 
Published: August 2024

Abstract

Introduction: The outbreak of Corona Virus Disease (COVID-19) in 2019 has continued until now, posing a huge threat to the public’s physical and mental health, resulting in different degrees of mental health problems. Previous studies have shown that insomnia is one of the main influences on anxiety. However, due to the specificity of the disease and the situation of centralized treatment of COVID-19 patients in mobile cabin hospitals, insomnia interventions are limited. Therefore, it is necessary to find the complex mediating variables between insomnia and anxiety to provide new ideas for the prevention and intervention of anxiety caused by insomnia in COVID-19 patients. Methods: The measurement tools were the Athens Insomnia Scale, Psychological Capital Questionna- ire, and Self-Rating Anxiety Scale. Statistical analysis was performed using SPSS 25.0 software, and a mediator model was established and corrected using Amos software. Results: More than one in five patients in this study had anxiety, and the total score was significantly higher than the Chinese standard total score. Insomnia was positively correlated with anxiety, but negatively correlated with psychological capital; and psychological capital was negatively correlated with anxiety. Psychological capital can act as a mediating factor in the relationship between insomnia and anxiety. Psychological capital played a mediating role in the relationship between insomnia and anxiety among COVID-19 patients, that is, insomnia not only directly affected anxiety, but also indirectly affected anxiety through the mediating role of psychological capital. Conclusion: It is recommended that patients and health care professionals increase the psychological capital of COVID-19 patients through various methods to counter the effects of insomnia on anxiety.
Illuminating Miliary Sarcoidosis: A Case Report
Authors: Sann Kyi Kyi , Arooj Parniya , Berry Matthew , Hougham Natasha , Coulter Sarah 
Published: August 2024

Abstract

Background
Sarcoidosis is a multisystem disease characterized by non-caseating granulomas, typically identified by peribronchovascular and perilymphatic nodules on high-resolution computed tomography (HRCT). Miliary sarcoidosis, an atypical presentation involving diffuse pulmonary infiltrates, is rarely reported, occurring in less than 1% of cases.
Case Presentation
We present a case of a 60-year-old Caucasian woman with unexplained weight loss, breathlessness, and cough. Initial chest CT revealed extensive hilar and mediastinal lymphadenopathy with diffuse pulmonary infiltrates, suggesting disseminated malignancy. However, subsequent PET-CT scans showed intense and widespread FDG avidity throughout the lungs and mediastinal nodes, indicative of miliary sarcoidosis. Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) confirmed non-caseating granulomas, leading to a diagnosis of sarcoidosis. The patient was treated with oral corticosteroids, resulting in significant clinical and radiological improvement.
Conclusion
This case underscores the importance of recognizing atypical imaging patterns in sarcoidosis, such as miliary distribution, to avoid misdiagnosis and ensure appropriate management. The combination of advanced imaging techniques and minimally invasive biopsy procedures is crucial for accurate diagnosis and effective treatment.
CT-detected masked otitis media in various clinical situations: a possible pathogenesis to be noted
Authors: Wang Jianyan , Chen Jia , Wang Wan , Chen Haoxin , Ye Na , Li Peng , Chen Yubin 
Published: August 2024

Abstract

Background: To analyze a series of CT-detected masked otitis media in various clinical situations in order to remind attention to this possible pathogenesis that is easy to be overlooked.
Methods: This is Case series.Charts of patients referred for different otological complaints, including ear discomforts, vertigo or facial nerve abnormality, with an intact tympanic membrane were reviewed. Complete record of clinical history and otological examinations were required. Those with High-resolution CT (HRCT) finding of masked otitis media, which seemed to be response for the patients’ complaints, were included in the analysis.
Results: A total of 15 cases of CT-detected masked otitis media were included for analysis. There were 12 cases with conductive or mixed hearing loss, 11 of which were presented asopacifications or sclerosing plaques involving the ossicles in HRCT. There were 2 cases considered as complications of otitis media, including one case of vertigo and one case of facial paralysis. Opacificationswere found in the round window niche and around the facial nerve respectively in HRCT. The remaining case merely complained of earache in the retroauricular region with normal hearing results, whose HRCT revealed Opacifications in partial mastoid cells.
Conclusion: Masked otitis media as a possible pathogenesis in various clinical situations should be remind enough attention to. A detailed disease history and comprehensive analysis of otological tests, especially the careful reading of the temporal HRCT, could provide important clues for the discrimination of masked otitis media.
Clinical analysis of the efficacy of bronchial artery embolization with gelatin sponge in our hospital for cryptogenic hemoptysis: a single-center, retrospective, observational study
Authors: Suzuki Manabu , Hatano Satoki , Morita Chie , Tsukada Akinari , Ishida Akane , Kusaba Yusaku , Hashimoto Masao , Naka Go , Takasaki Jin , Nokihara Hiroshi , Izumi Shinyu , Takeda Yuichiro , Hojo Masayuki , Sugiyama Haruhito 
Published: August 2024

Abstract

Background and objective: Hemoptysis is a life-threatening condition requiring urgent treatment. Bronchial artery embolization (BAE), established as the primary intervention, is an effective treatment for hemoptysis. Common etiologies include bronchiectasis, tumors, tuberculosis, aspergilloma, and cystic fibrosis. Approximately 20 % of hemoptysis cases are categorized as cryptogenic. We conducted a retrospective observational study to understand the clinical characteristics of patients with cryptogenic hemoptysis (CH).
Methods: The clinical characteristics, angiographic findings, and immediate and long-term efficacies of BAE were retrospectively analyzed in 36 consecutive patients between January 2010 and December 2022. Superselective BAE was successfully performed in all patients by using a gelatin sponge (GS).
Results: The median age was 68 years, and 21 patients (58.3 %) were male. Among them, 15 patients (41.7 %) presented with massive hemoptysis, and 7 (19.4%) required intubation. Angiographic evaluation revealed the treatment of total 57 vessels, comprising 51 (89.5%) bronchial arteries, 5 (8.8 %) intercostal arteries, and 1 (1.8 %) inferior transverse artery. The recurrence-free rates were 100 % at 1 month, 94.4 % at 3 months, 94.4 % at 12 months, and 86.1 % at more than 12 months. Only one patient required a second BAE for hemoptysis, while others were managed for recurrences with oral hemostatic agents. No serious complications, such as spinal cord infarction, were observed during the study period.
Conclusion: BAE treatment with GS for CH proved to be a suitable therapeutic modality, demonstrating high efficacy in halting bleeding in both the short and long terms, with the absence of severe complications, including spinal cord infarction.
The Effect of a Therapeutic Exercise Programme on Physical Function in Patients Undergoing a Haematopoietic Progenitor Cell Transplantation
Authors: Comesaña Antonio Chamorro , Fernández Noa Piñeiro , Fernández Patricia Rodríguez , García Natalia Fente , Losada Francisco Xosé Román , González Mª Carmen Quintela , Vázquez Agustín Nieto , López Ana Santamaría , Álvarez Judith Vázquez , Prieto Angela , López Carmen Albo 
Published: August 2024

Abstract

Objetive: Observe the effect of a therapeutic exercise (TE) programme on physical capacity of patients undergoing haematopoietic stem cell transplant (HSCT) 3 months after intervention.
Patients and methods: An observational study was carried out in patients who underwent a HSCT at the Álvaro Cunqueiro Hospital in Vigo (Spain) between September 2020 and August 2021. Patients were assessed before admission and 3 months after the transplant. 30-second chair stand test (30”CST) was used to measure lower body resistance, and timed up and go (TUG) to assess functional mobility and detect balance and coordination problems. During admission, patients completed the TE programme developed at the hospital based on guidelines from the Spanish Group for Transplantation and Cellular Therapy (GETH-TC).
Results: 34 patients were included. Three months after HSCT, a decrease in number of 30”CST repetitions from 11.58±4.09 to 10.94±3.54 (p<0.0001) and in time to perform the TUG from 9.86±5.56 to 8.65±3.30 seconds (p<0.0001) was recorded. Fewer incidents which required help were recorded (from 21 to 16).
Conclusions: A TE programme in HSCT is safe, can improve coordination and balance, and serves to mitigate the loss of muscle strength these patients tend to experience because of disease, the transplant process, and prolonged inactivity.
Unraveling the immunological roles of serum amyloid A3 in aortic immune cell subsets during atherosclerosis progression
Authors: Lin Jian-Da , Chou Tzu-Yin , Ye Yu-Zhen , Lin I-Jung , Lien Chia-Jung , Yang Chen-Hsuan , Chen Yen-Ting , Chao Pei-An 
Published: August 2024

Abstract

Atherosclerosis is a growing concern in developed nations, necessitating the identification of therapeutic targets for advancing personalized medicine. Serum amyloid A3 (Saa3) has been linked to accelerated plaque progression by affecting cholesterol metabolism and modulation of inflammation. We hypothesize that knocking out Saa3 (Saa3-/-) could mitigate plaque development by regulating aortic immune cell subsets during atherosclerosis progression. Using a murine model, we induced atherosclerosis via a gain-of-function mutant PCSK9-encoding adeno-associated viral vector (AAVmPCSK9) in wild-type (WT) and Saa3-/- mice. Single-cell RNA sequencing revealed that Saa3-/- mice developed smaller plaques than WT mice, with significant differences in aortic immune cell populations, particularly aortic macrophages. Saa3-/- macrophages, characterized by high Gpnmb, Lpl, and Spp1 expressions, predominated over the typical resident foamy macrophages in WT mice. Saa3-/- mice also showed enhanced intercellular immune communication and increased signaling interactions, suggesting a shift towards an anti-inflammatory and tissue-repairing phenotype. Our study highlights the potential of Saa3 as a therapeutic target for atherosclerosis.