bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh Profitabilitas, Leverage dan Sales Growth Terhadap Financial Distress Dengan GCG Sebagai Variabel Moderasi
Authors: Apriliake Cahaya Ratna , Desyana Gita , Astarani Juanda 
Published: July 2024

Financial distress merupakan situasi saat sebuah perusahaan atau individu mengalami kesulitan keuangan yang serius, yang dapat menghambat kemampuan mereka untuk memenuhi kewajiban keuangan sehingga dapat mengakibatkan kebangkrutan atau likuidasi. Financial menjadi aspek yang krusial dalam perusahaan karena memiliki dampak yang signifikan terhadap operasional, keberlanjutan, dan nilai perusahaan. Penelitian ini bertujuan untuk menganalisa pengaruh dari profitabilitas, leverage, dan sales growth terhadap financial distress serta menguji pengaruh moderasi dari good corporate governance. Populasi dari penelitian adalah perusahaan sektor consumer cyclicals yang tercatat di Bursa Efek Indonesia sebanyak 157 perusahaan mendapatkan 24 perusahaan dengan teknik purposive sampling dengan jumlah tahun selama 5 (lima) tahun dari periode 2019-2023. Teknik yang digunakan dalam analisis data yang digunakan adalah menganalisis data yang mencakup Uji Statistik Deskriptif, Uji Asumsi Klasik, Uji Regresi Linear Berganda, dan Uji Regresi Moderas Penelitian dilakukan menggunakan metode kuantitatif dengan pendekatan asosiatif dan analisis regresi linear berganda melalui SPSS Versi 29, pengumpulan data dilakukan dengan menggunakan data sekunder pada Bursa Efek Indonesia. Hasil dari penelitian menunjukkan profitabilitas dan sales growth berpengaruh positif, sedangkan leverage berpengaruh negatif terhadap financial distress. Uji moderasi menunjukkan bahwa good corporate governance dapat memperkuat pengaruh profitabilitas terhadap financial distress, serta tidak menunjukkan pengaruh terhadap hubungan leverage dan financial distress.
Marginalisasi Keberadaan Dari Profesi Akuntan Di Era Digitalisasi 5.0
Authors: Nurwidiani Nurwidiani , Hasanuddin Hasanuddin , Idrawahyuni Idrawahyuni 
Published: July 2024

Salah satunya adalah seorang akuntan. Tidak menutup kemungkinan 95% profesi akuntan akan tergantikan oleh robot. Penelitian ini bertujuan untuk mengetahui apakah profesi akuntan akan tergantikan oleh teknologi di era digitalisasi 5.0. Metode yang digunakan dalam penelitian ini adalah kualitatif dengan pendekatan fenomenologi. Adapun pengumpulan data dalam penelitian ini yaitu dokumentasi dan wawancara. Dan teknik analisis data yang digunakan dalam penelitian ini adalah pengumpulan data, reduksi data, penyajian data dan penarikan kesimpulan. Hasil penelitian ini menunjukkan bahwa keberadaan profesi akuntan tetap penting dalam memberikan penilaian, interpretasi, dan saran strategis berdasarkan data yang dihasilkan oleh teknologi. Profesi akuntan masih memegang peranan kunci dalam memastikan kepatuhan terhadap regulasi, menyediakan analisis mendalam, dan memberikan nasihat kepada perusahaan. Jadi, meskipun digitalisasi membawa perubahan signifikan dalam cara akuntan bekerja, mereka masih memiliki peran penting dalam memberikan nilai tambah bagi perusahaan dan klien mereka. Jadi keberadaan dari profesi akuntan di era digitalisasi 5.0 sangat tergantung pada seberapa baik profesi ini dapat beradaptasi dengan perubahan teknologi dan memanfaatkannya untuk meningkatkan layanan yang mereka tawarkan.
Evaluation of microbiome composition combined with serum untargeted metabolomic profiling in newly diagnosed children with inflammatory bowel disease
Authors: Zdanowicz Katarzyna , Pietrowska Karolina , Lebensztejn Dariusz Marek , Ciborowski Michal , Godzien Joanna , Kretowski Adam , Daniluk Jaroslaw , Daniluk Urszula 
Published: July 2024

IntroductionThe relationship between the intestinal microbiota, metabolites and inflammatory bowel disease (IBD) development is still being sought. We aimed to assess whether the gut microbiome and serum metabolic profile are consistent with a diagnosis of Crohn’s disease (CD) or ulcerative colitis (UC) in children with newly diagnosed disease.Material and methodsBacterial abundance in fecal samples was evaluated using a 16S rRNA DNA-based test in treatment-naive children with IBD (n=18) and healthy controls (n=10). Metabolic fingerprinting of serum samples of the same individuals was estimated using liquid chromatography coupled with mass spectrometry.ResultsIt was not possible to discriminate between CD and UC patients based on the gut microbiota profiles, but surprisingly, on the Principal Component Analysis (PCA) model we observed a spontaneous separation of IBD patients into two groups, independently of IBD type. Then, serum metabolic profiles of these two microbiota-based groups of IBD patients were compared using orthogonal partial least squares discriminant analysis (OPLS-DA) modelling. Good quality models were obtained based on serum metabolomics data collected in positive and negative ion mode data. In total, 12 metabolites significantly discriminating these groups were identified.ConclusionsBased on microbiota profiling a grouping of IBD patients, unrelated to the IBD type, was noted. These two groups also have specific serum metabolic profiles. Further studies are needed to assess whether IBD patients, depending on their gut microbiota and serum metabolite composition, require different treatments and if that impacts disease outcomes.
Upper-atmosphere responses to the 2022 Hunga Tonga–Hunga Ha′apai volcanic eruption via acoustic gravity waves and air–sea interaction
Authors: Li Qinzeng , Xu Jiyao , Gusman Aditya Riadi , Liu Hanli , Yuan Wei , Liu Weijun , Zhu Yajun , Liu Xiao 
Published: July 2024

Abstract. A multi-group of strong atmospheric waves (wave packet nos. 1–5) over China associated with the 2022 Hunga Tonga–Hunga Ha′apai (HTHH) volcano eruptions were observed in the mesopause region using a ground-based airglow imager network. The horizontal phase speed of wave packet nos. 1 and 2 is approximately 309 and 236 m s−1, respectively, which is consistent with Lamb wave L0 mode and L1 mode from theoretical predictions. The amplitude of the Lamb wave L1 mode is larger than that of the L0 mode. The wave fronts of Lamb wave L0 and L1 below the lower thermosphere are vertical, while the wave fronts of L0 mode tilt forward above the lower atmosphere, exhibiting internal wave characteristics which show good agreement with the theoretical results. Two types of tsunamis were simulated; one type of tsunami is induced by the atmospheric-pressure wave (TIAPW), and the other type of tsunami is directly induced by the Tonga volcano eruption (TITVE). From backward ray-tracing analysis, the TIAPW and TITVE were likely the sources of wave packet nos. 3 and 4–5, respectively. The scale of tsunamis near the coast is very consistent with the atmospheric AGWs observed by the airglow network. The atmospheric gravity waves (AGWs) triggered by TITVE propagate nearly 3000 km inland with the support of a duct. The atmospheric-pressure wave can directly affect the upper atmosphere and can also be coupled with the upper atmosphere through the indirect way of generating a tsunami and, subsequently, tsunami-generating AGWs, which will provide a new understanding of the coupling between ocean and atmosphere.
Why did ozone concentrations remain high during Shanghai's static management? A statistical and radical-chemistry perspective
Authors: Zhu Jian , Wang Shanshan , Gu Chuanqi , Jiang Zhiwen , Zhang Sanbao , Xue Ruibin , Yan Yuhao , Zhou Bin 
Published: July 2024

Abstract. During the period of April and May 2022, Shanghai implemented city-wide static management measures to control the spread of the Omicron variant. Compared to the lockdown in early 2020, the static management in 2022 occurred during the high-ozone season and lasted for a longer duration. It can be considered a “large-scale field experiment” to study the response of ambient ozone levels to emission reductions. During this period, we conducted comprehensive observations at Fudan University, Jiangwan Campus, in the northeast corner of Shanghai. Similar experiments were also conducted during the same period in 2020 and 2021. Despite the significant reduction of approximately 30 % in VOCs and around 50 % in NO2 due to static management in 2022, the average ozone level increased by nearly 23 % compared to 2020 and 2021. This suggests that the reduction in ozone precursors and other pollutants did not lead to a corresponding decrease in ozone concentrations as expected. Cluster analysis of diurnal patterns of ozone concentration revealed four distinct types of diurnal ozone variations. Cluster 3 and cluster 4, with high ozone levels, experienced significant increases in their shares during static management, ultimately leading to an overall increase in average ozone levels in 2022. According to the observation-based model (OBM) simulation analysis, the average peak concentrations of OH, HO2, and RO2 in 2022 were estimated to be 5.1×106, 4.7×108, and 2.6×108 molec.cm-3, respectively, representing an increase of about 30 % compared to the levels in 2020 and 2021. Although HONO photolysis was the main contributor to the primary source of ROx radicals, the radical-cycling process remained dominant for the overall production of ROx radicals. Due to a significant decrease in NO2 concentration relative to VOCs, the average VOC / NO2 ratio increased from 1.6 in 2020 to 3.0 in 2022, which is also reflected in the radical cycling. The ratio of OH radical propagation (OH + VOCs) to termination (OH + NO2) was 2.37, higher than 1.18 in 2020 and 1.78 in 2021, indicating that the different reduction proportions of precursors led to a higher VOC / NO2 ratio, strengthening the radical cycling. The differential reduction in precursor VOCs and NO2 levels due to static management is the underlying cause of the increase in ozone concentration in Shanghai.
Impact of reservoir evaporation on future water availability in north-eastern Brazil: a multi-scenario assessment
Authors: Rodrigues Gláuber Pontes , Brosinsky Arlena , Rodrigues Ítalo Sampaio , Mamede George Leite , de Araújo José Carlos 
Published: July 2024

Abstract. The potential effects of climatic changes on water resources are crucial to be assessed, particularly in dry regions such as north-east Brazil (1 million km2), where water supply is highly reliant on open-water reservoirs. This study analyses the impact of evaporation (by the Penman method) on water availability for four scenarios based on two regional climatic models (Eta-CanESM2 and Eta-MIROC5) using the Representative Concentration Pathways (RCPs) 4.5 and 8.5. We compared the water availability in the period of 2071–2100 with that of the historical period (1961–2005). The scenarios derived from the Eta-CanESM2 model indicate an increase in the dry-season evaporative rate (2 % and 6 %, respectively) by the end of the century. Unlike the above scenarios, the ones derived from the Eta-MIROC5 model both show a change in the dry-season evaporative rate of −2 %. Consequently, for a 90 % reliability level, the expected reservoir capacity to supply water with high reliability is reduced by 80 %. It is reasonable to state that both patterns of future evaporation in the reservoirs may prove to be plausible. Because model-based projections of climate impact on water resources can be quite divergent, it is necessary to develop adaptations that do not need quantitative projections of changes in hydrological variables but rather ranges of projected values. Our analysis shows how open-water reservoirs might be impacted by climate change in dry regions. These findings complement a body of knowledge on the estimation of water availability in a changing climate and provide new data on and insights into water management in reservoir-dependent drylands.
Pensamiento computacional a través de STEAM con Sphero
Authors: Gutiérrez-Núñez Sandra Erika , Rincón Zuluaga Joam Manuel 
Published: July 2024

Este estudio investiga cómo la metodología STEAM con robots Sphero impacta el desarrollo del pensamiento computacional (PC) en preadolescentes de 11 a 13 años de Ciudad Juárez, Chih., México. La hipótesis principal es que el nivel de PC de los participantes en esta investigación mejorará significativamente después de tomar un taller STEAM con Sphero, con miras a responder: las condiciones de impacto, la influencia del diseño instruccional y los aspectos de mayor contribución. Para el desarrollo del estudio, participaron 67 preadolescentes y se caracteriza por ser un diseño experimental con evaluaciones de PC antes y después de la intervención. Los resultados indican que los participantes no mejoraron significativamente en PC, ya que no pudieron resolver los problemas del examen final, con lo cual, se identificó la necesidad de hacer explícitos los elementos del PC durante las clases, como identificación de problemas, abstracción, descomposición, reconocimiento de patrones, creación de algoritmos, depuración e iteración. El estudio concluye que es fundamental introducir explícitamente estos conceptos en las secuencias STEAM y asegurar suficiente práctica con cada concepto de programación, ya que la estructura tradicional de la clase de programación no prepara adecuadamente a los estudiantes, contribuyendo a la deserción escolar
Rising Costs and Diminishing Surgeon Reimbursement From Primary to Revision Total Hip and Knee Arthroplasty: An Analysis of Medicare Advantage and Commercial Insurance
Authors: Parikh Nihir , Hobbs John , Gabrielli Alexandra , Sakaria Samir , Wellens Bryan , Krueger Chad A. 
Published: July 2024

Background:
Revision total joint arthroplasty (rTJA) is a resource-intensive procedure addressing failed primary total joint hip (total hip arthroplasty [THA]) and knee arthroplasty (total knee arthroplasty [TKA]). Despite predictions of increased demand, reimbursement for rTJA has not kept pace with increasing costs and may be insufficient compared with primary procedures. The study aimed to highlight the diminishing surgeon reimbursement between primary and revision THA (rTHA) and TKA.

Methods:
This study is a retrospective analysis of billing data for primary and rTHA and TKA procedures from a single institution between 2019 and 2022. Insurance claims and charges data were provided by a local affiliate of a major national carrier which includes Medicare Advantage (MA) and commercial patients. Using insurance data, the study evaluates the total surgery costs for primary and rTHA and TKA and the individual charges that make up the total surgery cost.

Results:
Nine hundred five patients insured by the same carrier, who underwent a primary or rTJA, were identified. Irrespective of MA or commercial insurance, the average surgery cost for a primary THA was $26,043, compared with $53,456 for rTHA. Surgeon reimbursement for primary THA was 20% ($5,323) of the total surgery cost. Despite the doubled surgery cost for rTHA, surgeon reimbursement was 10% ($5,257) of the total surgery cost. Primary TKA surgery costs were $24,489, while revision costs were $43,074. Surgeon reimbursement for primary TKA was 20% ($4,918) of the total surgery cost, while reimbursement for revision TKA was 13% ($5,560). MA reimbursement was markedly lower than commercial reimbursement for primary and revision cases.

Conclusion:
Despite the higher total costs for rTJA, surgeon reimbursement is disproportionately diminished. The findings highlight the lack of incentive for revision cases. Surgeon reimbursement from MA and commercially insured patients for rTJA remains inadequate. This may limit patient access-to-care, leading to suboptimal outcomes and increased healthcare utilization.
NRP1 como potencial alvo molecular para meduloblastoma
Authors: De Araujo Moisés Augusto , Nassif Paulo Afonso Nunes , Fratini Livia , Roesler Rafael , Rabello Samuel , Carmo Alexsandro Batista da Costa , Isolan Gustavo Rassier 
Published: July 2024

Introdução: Meduloblastoma é tumor maligno, altamente agressivo e de rápido crescimento que surge no cerebelo ou no assoalho do quarto ventrículo e tronco cerebral, especialmente em crianças. Mesmo com avanços na terapia, a morbimortalidade permanece grande desafio. Por isso, novos tratamentos são necessários para reduzir esses desfechos.
Objetivo: Revisar a relação NRP1 (neuropilina 1) e meduloblastoma como potencial alvo terapêutico e, também, com sobrevida global.
Método: Trata-se de revisão narrativa realizada nas bases de dados PubMed e Scielo. A busca utilizou as seguintes palavras-chave: “neuropilinas, meduloblastoma, tumores cerebrais, pediatria”. Os critérios de inclusão foram artigos de revisão, estudos experimentais, pesquisas pré-clínicas e clínicas, em inglês e português, e disponíveis em texto completo. Os artigos selecionados foram analisados com base nas tecnologias abordadas, perspectivas futuras e desafios mencionados, doenças referidas e ideia central do artigo.
Resultado: Foram incluídos 30 artigos
Conclusão: Os meduloblastomas possuem altos níveis transcricionais de neuropilina (NRP1) e seus baixos níveis relacionam-se com menor sobrevida global, especialmente nos SHH. Nesse sentido, a NRP1 e seu complexo sistema de atuação aparece como potencial alvo de terapias oncológicas para tumores cerebrais.
Ensino de Química, Física e Biologia em escolas públicas
Authors: Camargo Marcio Antonio Ferreira , Camargo Carmen Aparecida Cardoso Maia , Pereira Vinícius Nascimento , Lemos Daniel Henrique Rattis 
Published: July 2024

As disciplinas de Química, Física e Biologia apresentam como gargalo no Ensino Médio conteúdos desafiadores durante os primeiros anos. Associado a isso, destaca-se a falta de infraestrutura, tanto em aspectos físicos, como falta de laboratórios, quanto em recursos materiais. O estudo busca avaliar as principais dificuldades enfrentadas pelos professores no processo de ensino-aprendizagem na área de conhecimento das Ciências da Natureza. Trata-se de uma pesquisa exploratória, de abordagem quantitativa e foi realizada nas escolas da rede pública localizadas em uma cidade do sudoeste mineiro, através de plataformas virtuais devido à pandemia do patógeno Sars-Cov2, causador da COVID-19. O instrumento de coleta de dados foi um questionário online fechado, contendo 6 blocos de questões objetivas, aplicado aos docentes acerca de suas vivências em sala de aula. Os obstáculos encontrados – políticos, sociais e educacionais – revelam os desafios para a sua prática e reforçam como a intensa fragmentação e padronização do ensino atuam como agentes antagonistas desse processo e como a liberdade e autonomia da gestão escolar agem na resolução de tais impasses. Observou-se que as práticas pedagógicas utilizadas no ensino das Ciências da Natureza, na avaliação da maioria dos professores pesquisados, seguem um modelo tradicional do ensino, mediante a apresentação de conceitos, leis e fórmulas de forma desarticulada, distante do cotidiano dos alunos.
Nocebo effect as the opposite of the placebo effect: Systematic review
Authors: França Drissen Viviani , Sabattini Analia Claudia 
Published: July 2024

Background: the placebo effect refers to a clinical improvement in a patient as a result of interactions with the treating physician, information received about the treatment, and the defined therapy. The placebo effect is a broad field involving complex neurobiological and neurotransmitter mechanisms, and recent studies have provided evidence that these effects are genuine biopsychosocial phenomena. Although placebos cannot cure a disease, they can provide relief to the patient and improve the effectiveness of pharmaceuticals. The effectiveness of placebos depends on several factors, including the patient's age, psychological and emotional state, the doctor's approach, and the information provided to the patient. The nocebo effect, which generates an adverse response to this type of treatment, which can be defined as the effect opposed to placebo. Method: an exhaustive search was carried out in PubMED and a synthesis of the available evidence on the neurobiological factors associated with the nocebo effect. For this, a systematic review was carried out. Results: after manual selection, 4 articles were reviewed for the preparation of results.Conclusion: therapeutic interaction, facial expressions, and eye contact influence placebo analgesia. The patient's expectation, based on the physician's information and nonverbal cues, is crucial in the placebo response. Variables such as age and psycho-emotional state reduce the efficacy of the placebo. The nocebo effect causes adverse responses related to negative expectations. The presentation of medical information influences the nocebo response. Cognitive behavioral treatments and medications can reduce nocebo effects. These determinations have implications for the treatment of psychiatric conditions and medication management
Systematic review protocol of digital divides in the medical sciences area
Authors: Alcides Loayza-Effio Jorge Alcides , Huayta-Franco Yolanda Josefina , Flores-Sotelo Willian Sebastian 
Published: July 2024

Introduction: the development of digital technologies in the area of medical sciences has progressively advanced in recent years, initially conceptualized as electronic health, whose characteristics were fundamentally informative, its main tool being the internet and extending to other services such as mobile health and telehealth of great importance for medicine. Objective: the present systematic review aims to determine the main digital technologies in the health area, developed during the years 2020 to 2022 and their applicability in the different fields of medicine.Method: the methodology used was based on the review of original research articles on four categories of study: electronic medical records, telemedicine, mobile health and data analysis, obtained from the Scopus, Web of Science, ProQuest and EBSCO databases. Thirty articles were selected, respecting the screening and eligibility criteria considered in the PRISMA protocol. Results: the results of the review showed the remarkable development in the application of electronic medical records and telemedicine in the different areas of health, constituting between them 60 % of the publications; mobile applications and data analysis were the ones with the lowest results, but with the greatest technological innovation. Conclusion: we conclude the importance of the applicability of new technologies developed during the health emergency in different health areas