bluuebunny/crossref_metadata_2025_split huggingface dataset:
An Analysis of Factors Affecting the Duration of Latency Period and Its Impact on Neonatal Outcome in Patients with PPROM
Authors: Gami Neha , Singhal Seema 
Published: March 2013

ABSTRACTIntroductionPreterm premature rupture of membranes (PPROM) complicates approximately 3% of all births, but accounts for 30% of neonatal morbidity and mortality among premature gestations. Prediction of latency period for women with PPROM is imprecise and therefore consulting women with PPROM about their predicted latency period is a difficult task. The studies are limited, thus more information is required to support clinical decisions and to provide prognostic information in cases of expectant management following PPROM.Materials and methodsWe conducted a prospective observational study of women with singleton pregnancies presenting with rupture of membranes. A total of 120 women presenting with PPROM from 26 to 36 weeks with rupture of membrane were included in this study.ResultsAdvanced maternal age >30 years was found to be associated with prolongation of latency period (p = 0.000). Nulliparity was found to be associated with shortening of latency period (p = 0.012). An inverse association between gestational age at the time of presentation and latency period was established. The average gain in duration of latency period by not doing a digital examination was found to be statistically significant (p = 0.000). Gestational age and duration of latency period were found to be the important predictors of neonatal outcome.ConclusionIn the current study, several predictive factors were identified which affect the duration of the latency period in cases of PPROM. This information may assist clinician in risk stratification and in providing consultation regarding the natural course of expectant management for women presenting with PPROM.How to cite this articleSinghal S, Puri M, Gami N. An Analysis of Factors Affecting the Duration of Latency Period and Its Impact on Neonatal Outcome in Patients with PPROM. Int J Infertility Fetal Med 2012;3(3):87-91.
How Far above the True Anatomic Position can the Acetabular Cup be Placed in Total Hip Arthroplasty?
Authors: Fukui Kiyokazu , Kaneuji Ayumi , Sugimori Tanzo , Ichiseki Toru , Matsumoto Tadami 
Published: March 2013

Introduction There is controversy about which is more suitable for determining correct socket position in patients with severe bone deficiency of the acetabular roof because of developmental dysplasia of the hip (DDH): the anatomic centre of hip rotation or a high centre. Method We evaluated the relationship, in 200 hips, between the centre of rotation and presence of the Trendelenburg sign to determine the upper limit of cup position from the standpoint of hip-abductor strength. Results Of the 200 hips, 20 (10%) showed a positive Trendelenburg sign. There were no statistically significant differences between parameters (the centre of rotation, femoral offset, abductor lever arm) regarding the presence of the Trendelenburg sign except for age at surgery. Patients with a positive Trendelenburg sign were significantly older (64.1 ± 9.4 years) than those with a negative Trendelenburg sign (58.8 ± 7.7 years) (P = 0.01). Conclusions Our findings indicate that a high centre of hip rotation of up to approximately 30 mm from the inter-teardrop line is a feasible option for patients with DDH from the standpoint of hip-abductor strength if stems are used that allow the restoration of femoral offset and the abductor lever arm.
Appartenance professionnelle et articulation travail/famille. Comparaison de deux groupes professionnels : les infirmières et les policiers
Authors: Fusulier Bernard , Sanchez Émilie , Ballatore Magali 
Published: March 2013

Cet article étudie la relation entre la vie professionnelle et la vie familiale en privilégiant une entrée par la profession afin de mettre en avant l’impact des spécificités de l’appartenance professionnelle sur la manière de vivre et de gérer cette relation et les tensions sous-jacentes. Pour ce faire, les auteurs prennent appui sur une enquête par questionnaire réalisée en Belgique francophone auprès de 314 infirmières-parents et de 284 policiers-parents. Ils montrent qu’au côté des différences entre les hommes et les femmes, l’appartenance professionnelle induit tendanciellement des ressentis et des modes d’atténuation de la tension en matière d’articulation de la vie professionnelle avec la vie familiale (APF) différents. Les différences observées permettent d’opposer au final deux grands modes de régulation de cette APF : l’un à caractère séquentiel dans le milieu infirmier; l’autre à caractère intégratif dans le milieu policier.
Régimes collectifs de rémunération variable, justice organisationnelle et engagement
Authors: Caron Isabelle , Ben Ayed Ahmed Khalil , Vandenberghe Christian 
Published: March 2013

Cette étude examine les relations entre les caractéristiques des régimes collectifs de rémunération variable à court terme (soit des régimes qui octroient une prime aux employés en fonction du rendement), la justice organisationnelle et l’engagement organisationnel. Son intérêt pratique repose sur l’idée que les régimes de rémunération variable sont instaurés pour fidéliser les employés. À partir d’une revue de la littérature, quatre caractéristiques des régimes collectifs de rémunération variable sont identifiées : 1) le lien d’instrumentalité perçu (perception d’un lien entre le rendement et la rémunération); 2) la prime versée (le montant versé à l’employé dans le cadre du régime); 3) l’intensité de la communication organisationnelle (les sources d’information mises à la disposition des employés); et 4) les communications du supérieur immédiat relativement au régime de rémunération. Notre hypothèse centrale est que ces caractéristiques sont liées à l’engagement affectif et de continuité des employés par l’entremise de quatre dimensions de justice organisationnelle, soit la justice distributive, la justice procédurale, la justice informationnelle et la justice interpersonnelle.À partir d’un échantillon de 313 répondants appartenant à trois ordres professionnels, des analyses d’équations structurelles révèlent que la justice procédurale médiatise la relation entre 1) l’intensité de la communication organisationnelle et la communication du supérieur et 2) l’engagement de continuité. De même, la justice informationnelle médiatise la relation entre 1) l’intensité de la communication organisationnelle et la communication du supérieur et 2) l’engagement affectif. Enfin, la justice interpersonnelle médiatise la relation entre la communication du supérieur et l’engagement de continuité. Cette étude montre que la communication par l’organisation et le supérieur immédiat quant aux règles régissant le fonctionnement des régimes collectifs de rémunération variable constituent la pierre angulaire de la perception de justice (procédurale, informationnelle et interpersonnelle) par les employés, ce qui indirectement stimule leur engagement affectif et de continuité.
La précarisation du travail : des parcours professionnels à géométrie variable
Authors: Thirot Myriam 
Published: March 2013

Le développement des emplois « atypiques » au Québec donne lieu à la mise en évidence de nouveaux enjeux sociaux et politiques dans un contexte de flexibilité de la main-d’oeuvre. La segmentation du marché du travail qui en découle se caractérise par une précarisation du salariat, définie comme un processus structurel de détérioration des conditions de travail et d’emploi. La sociologie s’intéresse particulièrement aux conséquences de ces mutations sur les conditions de vie à travers l’analyse des perceptions subjectives des acteurs concernés. Ainsi, le rapport au travail incluant les conditions matérielles, l’accomplissement des tâches et la socialisation comporte une dichotomie articulée autour de la satisfaction du salarié, source de valorisation ou de la non-satisfaction, entraînant un mal-être. Les transformations récentes du monde du travail construisent des parcours professionnels morcelés et incertains et nécessitent une réévaluation de leurs impacts sur ce rapport, encore peu documentée. Que signifie occuper un emploi atypique pour ces travailleurs ? La valeur associée au travail est-elle remise en cause ? Les indices contenus dans leurs parcours professionnels constituent-ils une réalité nouvelle ? Basé sur les résultats d’une recherche qualitative menée en 2009 auprès de résidents d’un quartier défavorisé du centre-ville de Montréal, ayant occupé des emplois « atypiques », cet article permet d’entrer au coeur des dynamiques relationnelles des milieux de travail québécois, de comprendre en quoi elles participent à la construction de parcours professionnels spécifiques et d’identifier leurs conséquences sur le rapport au travail et à l’emploi de ces travailleurs. Les différentes expériences étudiées apportent un éclairage sur le phénomène de la précarisation du travail et suggèrent des perspectives tant scientifiques que politiques.
Graphene at the Atomic‐Scale: Synthesis, Characterization, and Modification
Authors: Iski Erin V. , Yitamben Esmeralda N. , Gao Li , Guisinger Nathan P. 
Published: March 2013

AbstractGraphene is nature's ideal two‐dimensional conductor and is comprised of a single sheet of hexagonally packed carbon atoms. Since the first electrical measurements made on graphene, researchers have been trying to exploit the unique properties of this material for a variety of applications that span numerous scientific and engineering disciplines. In order to fully realize the potential of graphene, large scale synthesis of high quality graphene and the ability to control the electronic properties of this material on a nanometer length‐scale are necessary and remain key challenges. This article will review the efforts at the Center for Nanoscale Materials that focus on the atomic‐scale characterization and modification of graphene via scanning tunneling microscopy and its synthesis on various materials (SiC, Cu(111), Cu foil, etc.). These fundamental studies explore growth dynamics, film quality, and the role of defects. The chemical modification of graphene following exposure to atomic hydrogen will also be covered, while additional emphasis will be made on graphene's unique structural properties.
Trisomy 22 Mosaicism and Normal Developmental Outcome: Report of Two Patients and Review of the Literature
Authors: Abdelgadir Dalal , Nowaczyk Malgorzata J.M. , Li Chumei 
Published: March 2013

AbstractMosaic trisomy 22 is known to be compatible with life. However, there are fewer than 20 reports in the literature of live born children and even fewer reports describing their neurodevelopmental outcome. We report on two girls with mosaic trisomy 22 and normal development at ages 7 and 5 years. Both girls had characteristic dysmorphic features including flat nasal bridge, preauricular pits, epicanthic folds, and 5th finger clinodactyly. They also had left‐sided hemihyperplasia and short stature. In addition, one of them also had ventricular non‐compaction and probable asplenia, two unique features not previously reported. In review of the literature, prenatal and postnatal growth failures were the most common complications of mosaic trisomy 22. Skeletal abnormalities including body asymmetry and 5th finger clinodactyly were also common. While the majority of patients with mosaic trisomy 22 had abnormal cognitive development, normal development has also been documented. It is conceivable that children with trisomy 22 mosaicism, with minimal physical findings and normal development are under diagnosed. Our patients further highlight this potential for normal cognitive outcome and draw attention to possible skewing of unfavorable prognosis for the final developmental outcome in this population. Appropriate information regarding developmental outcome is critical for genetic counseling, especially in prenatal situations. © 2013 Wiley Periodicals, Inc.
Improvement of CNS Defects Via Continuous Intrathecal Enzyme Replacement by Osmotic Pump in Mucopolysaccharidosis Type II Mice
Authors: Sohn Young Bae , Lee Jeehun , Cho Sung Yoon , Kim Su Jin , Ko Ah‐Ra , Nam Mi Hyun , Jin Dong‐Kyu 
Published: March 2013

AbstractMucopolysaccharidosis type II (MPS II), also known as Hunter syndrome (OMIM 309900), is a rare, X‐linked lysosomal storage disorder caused by a deficiency of iduronate‐2‐sulfatase (IDS; EC 3.1.6.13), which is involved in the lysosomal degradation of glycosaminoglycans (GAG). Although intermittent intrathecal (IT) injection of the enzyme has been introduced as a method to overcome the blood‐brain barrier, continuous IT infusion of the enzyme would be more physiologic. This study was performed to investigate responses in the brain of MPS II mice to varying doses of continuous IT infusion of recombinant human IDS (rh‐IDS) in MPS II mice by osmotic pump in three different doses (2.4, 4.8, and 12 µg/day) of rh‐IDS for 3 weeks. The results showed that the group treated with 12 µg/day doses of rh‐IDS demonstrated decreased GAG concentrations compared to the untreated KO mice group (P = 0.003). After 3 weeks of continuous IT ERT, the brain tissues of the high‐dose IT‐treated KO mice showed a reduction of vacuolation in the cerebral cortex, thalamus and cerebellar cortex, which was not observed in the low‐ and medium‐dose KO mice groups. Moreover, the anti‐NeuN signal representing intact neuron was restored in the cortexes of the high‐dose group. In conclusion, continuous IT infusion of the deficient enzyme was effective in improving CNS defects in the MPS II mice, and could be a valuable therapeutic method for treating neurological deterioration in patients with MPS II. © 2013 Wiley Periodicals, Inc.
Rethinking Antillothrix: The Mandible and Its Implications
Authors: Rosenberger Alfred L. , Klukkert Zachary S. , Cooke Siobhán B. , Rímoli Renato 
Published: March 2013

AbstractA mandible of the Hispaniolan primate Antillothrix bernensis, virtually complete and providing the only definitive evidence of the species' lower dentition, has been discovered in a submerged Dominican Republic cave. The new specimen enables a more certain assessment of the species' phylogenetic position than previously possible. It belongs to the same individual as the nearly complete young adult cranium and postrcranial elements found earlier at the same site. Of the extinct Caribbean platyrrhines, the jaw compares well with partial mandibles representing Xenothrix mcgregori, from Jamaica. Among living platyrrhines, it closely resembles Callicebus and Aotus, as documented in a biometric analysis employing three‐dimensional geometric morphometrics of Callicebus, Aotus, Pithecia, Chiropotes, Cacajao, Cebus, and Saimiri. The jaw falls within the morphological variability of Callicebus and Aotus in this three‐dimensional analysis, is otherwise most similar to Pithecia, and is distinct from cebines. Lower molars resemble the Haitian primate, Insulacebus, a genus known by a full dentition and gnathic fragments with a pattern of derived features also present in Xenothrix. Considering the available craniodental and postcranial evidence, we conclude that Antillothrix is not properly classified as cebid but rather is best grouped with Pitheciidae, an idea long central to discussions of the phylogenetic affinities of the Greater Antillean primates. Since Antillothrix and Insulacebus are more primitive anatomically than the highly modified Xenothrix, it is tempting to surmise that the origins of the latter involved a vicariance or dispersal event via Hispaniola isolating it on Jamaica. Am. J. Primatol. 75:825–836, 2013. © 2013 Wiley Periodicals, Inc.
Nasopalatine Ducts and Flehmen Behavior in the Mandrill: Reevaluating Olfactory Communication in Old World Primates
Authors: CHARPENTIER MARIE J.E. , MBOUMBA SYLVÈRE , DITSOGA CLAUDE , DREA CHRISTINE M. 
Published: March 2013

AbstractCompared to other modes of communication, chemical signaling between conspecifics generally has been overlooked in Old World primates, despite the presence in this group of secretory glands and scent‐marking behavior, as well as the confirmed production and perception of olfactory signals. In other mammalian species, flehmen is a behavior thought to transport primarily nonvolatile, aqueous‐soluble odorants via specialized ducts to the vomeronasal organ (VNO). By contrast, Old World primates are traditionally thought to lack a functional VNO, relying instead on the main olfactory system to process volatile odorants from their environment. Here, in the mandrill (Mandrillus sphinx), we document unusual morphological and behavioral traits that typically are associated with the uptake of conspecific chemical cues for processing by an accessory olfactory system. Notably, we confirmed that both sexes possess open nasopalatine ducts and, in response to the presentation of conspecific odorants, we found that both sexes showed stereotyped behavior consistent with the flehmen response. If, as in other species, flehmen in the mandrill serves to mediate social or reproductive information, we expected its occurrence to vary with characteristics of either the signaler or receiver. Flehmen, particularly in a given male, occurred most often in response to odorants derived from male, as opposed to female, conspecifics. Moreover, odorants derived during the breeding season elicited more flehmen responses than did odorants collected during the birthing season. Lastly, odorants from reproductively cycling females also elicited more responses than did odorants from contracepted females. Although confirming a link between the nasopalatine ducts, flehmen behavior, and olfactory processing in mandrills would require further study, our observations provide new information to suggest anatomical variability within Old World primates, calling further attention to the underappreciated role of chemical communication in this lineage. Am. J. Primatol. 75:703‐714, 2013. © 2013 Wiley Periodicals, Inc.
Cell age–specific vulnerability of neurons to anesthetic toxicity
Authors: Hofacer Rylon D. , Deng Meng , Ward Christopher G. , Joseph Bernadin , Hughes Elizabeth A. , Jiang Connie , Danzer Steve C. , Loepke Andreas W. 
Published: March 2013

ObjectiveAnesthetics have been linked to widespread neuronal cell death in neonatal animals. Epidemiological human studies have associated early childhood anesthesia with long‐term neurobehavioral abnormalities, raising substantial concerns that anesthetics may cause similar cell death in young children. However, key aspects of the phenomenon remain unclear, such as why certain neurons die, whereas immediately adjacent neurons are seemingly unaffected, and why the immature brain is exquisitely vulnerable, whereas the mature brain seems resistant. Elucidating these questions is critical for assessing the phenomenon's applicability to humans, defining the susceptible age, predicting vulnerable neuronal populations, and devising mitigating strategies.MethodsThis study examines the effects of anesthetic exposure on late‐ and adult‐generated neurons in newborn, juvenile, and adult mice, and characterizes vulnerable cells using birth‐dating and immunohistochemical techniques.ResultsWe identify a critical period of cellular developmental during which neurons are susceptible to anesthesia‐induced apoptosis. Importantly, we demonstrate that anesthetic neurotoxicity can extend into adulthood in brain regions with ongoing neurogenesis, such as dentate gyrus and olfactory bulb.InterpretationOur findings suggest that anesthetic vulnerability reflects the age of the neuron, not the age of the organism, and therefore may potentially not only be relevant to children but also to adults undergoing anesthesia. This observation further predicts differential heightened regional vulnerability to anesthetic neuroapoptosis to closely follow the distinct regional peaks in neurogenesis. This knowledge may help guide neurocognitive testing of specific neurological domains in humans following exposure to anesthesia, dependent on the individual's age during exposure. ANN NEUROL 2013;73:695–704
Raman Spectroscopic Insights into the Chemical Gradients within the Wound Plug of the Green Alga Caulerpa taxifolia
Authors: Weissflog Ina A. , Grosser Katharina , Bräutigam Maximilian , Dietzek Benjamin , Pohnert Georg , Popp Juergen 
Published: March 2013

AbstractThe invasive unicellular green macroalga Caulerpa taxifolia has spread dramatically in the Mediterranean Sea over the last decades. Its success is based on rapid plug formation after wounding, to prevent the loss of cell content. This quick and efficient process involves the rapid transformation of the secondary metabolite caulerpenyne to the reactive 1,4‐dialdehyde oxytoxin 2, which acts as a protein crosslinker. The main metabolites of the wound plug were identified as proteins, caulerpenyne derivatives, and sulfated polysaccharides. Because of a methodological deficit, however, the detailed distribution of the compounds within the wound plug of C. taxifolia was unknown. This study demonstrates the suitability of FT‐Raman spectroscopy for the noninvasive in vivo determination of caulerpenyne and its derivatives, as well as β‐carotene, from signals with special spectral features within the wound plug and the adjacent intact alga tissue, with a resolution of 100 μm. FT‐Raman spectra allowed four different zones with distinct chemical compositions around the region of wounds to be characterized. Gradients of the investigated metabolites within the wound plug and the alga could be determined. Moreover, various caulerpenyne derivatives could be identified spectroscopically, and this has led to a mechanistic proposal for the internal and the external wound plug formation.
Hybrid endovascular repair for aortic arch pathology: Intermediate outcomes and complications
Authors: Kang Woong Chol , Shin Eak Kyun , Park Chul‐Hyun , Kang Jin Mo , Ko Young‐Guk , Choi Donghoon , Youn Young Nam , Shim Won‐Heum 
Published: March 2013

ObjectivesTo evaluate the outcomes of hybrid endovascular repair for aortic arch pathology.MethodsThis study was a retrospective analysis involving patients who underwent hybrid endovascular repair for aortic arch pathologies.ResultsTwenty‐one patients (16 men; mean age, 64.7 ± 16.2 years) with aortic arch pathologies were treated by hybrid endovascular repair. The indications for treatment included increased aneurysm size in 16 cases (71.4%), rupture or impending aneurysmal rupture in 5 cases (23.8%), and rapid growth of aortic dissection (≥10 mm/y) in 1 case (4.8%). Supra‐aortic vessel transposition and stent‐graft implantation were achieved in all cases. Two types of stent‐graft was used, as follows: the Seal thoracic stent‐graft in 14 patients (66.7%); and the Valiant stent grafts in 7 patients (33.3%). Perioperative complications affected 5 patients (23.8%), as follows: bleeding (n = 4, 19.0%); stroke (n = 3, 14.3%); renal failure (n = 2, 9.5%); vascular injury (n = 1, 4.8%), and respiratory failure (n = 1, 4.8%). Two patients died within 30 days (9.5%). Technical success was achieved in 15 patients (71.5%). Early endoleaks were noted in 4 patients (19.0%). One patient died during follow‐up (mean, 21.3 ± 11.6 months) due to a de novo intramural hematoma. Persistent early endoleaks were noted in 4 patients (19.0%); 2 of the 4 patients were successfully managed with implantation of additional stent‐grafts. No late onset endoleaks were noted. The death‐free survival and reintervention‐free survival rates during follow‐up were 85.7% and 90.5%, respectively.ConclusionHybrid treatment with supra‐aortic vessel transposition and endovascular repair may be an option in frail patients in who open procedures is too risky. © 2013 Wiley Periodicals, Inc.