bluuebunny/crossref_metadata_2025_split huggingface dataset:
A closer observation of the dedicated responsibilities of nurses at public hospitals in Bangladesh
Authors: Parvin Shahinur , Murshida  , Rahman M. Atiqur , Sumi Sharmin Akter , Kpekura Stephen , Mahmood Zeshaan Yahaya Haji , Ali M. Ahasan 
Published: July 2024

Background: Nurses are important health caregivers in Bangladesh. They help to improve health-facilities every day and reach it to helpless people. This study aimed to assess the responsibilities of professional nurses in public health hospitals.
Methods: The descriptive cross-sectional study conducted at Rajshahi Medical College (RMCH), Bangladesh from 18 September 2018 to 19 February 2019 included 300 individuals with following inclusion and exclusion criteria. A pre-tested questionnaire was used as a tool for data collection.
Results: Majority of participants age range of 31-40y 46.33%, 41-50y 27%, 20-30y, and 51-60y 19% and 7.67%, respectively. Moreover, Female are 96.33% and males constitute only 7.74%. Based on religion, Muslim 87%, Hindu 10%, Christian 1.67%, and Buddhist 1.33%. Beginning of education, diploma was compared to very few with advanced training for instance Master's and Ph.D. 38.67% nurses were 1-5 years of experience. But only 11 had ≥21 years of experience. A significant portion, 48.02%, had a good level of assessment of patients and 36.67% of individuals excelled at a high level of proficiency. While only 2% showed an inferior level of patient assessment. Improvement of quality care, the majority of respondents 48.33% good, 17.67% excellent, 21.67% average, and 3.33% poor quality care.
Conclusions: Nurses are the key element of the healthcare system. The study outcomes showing their best to provide quality service despite of lack of resources. If the responsible authority has a deep look at this domain, in the future they could make a role model in Bangladesh.
Enhancing competitive advantage through a strategic product ‎portfolio ‎and design for variety in weather radar products
Authors: Azami Marzieh , Karbasian Mahdi , Yousefian Sareh 
Published: July 2024

Background: In today's competitive industrial landscape, companies are focusing on developing diverse product portfolios to maintain a competitive edge. This trend has led to the adoption of product portfolio strategies aimed at enhancing customer satisfaction and optimizing resource utilization.
Methods: This study introduces a model to enhance the design of weather radar products by integrating DEMATEL and Goal Programming (GP). The methodology involves identifying key indicators of variety in weather radar design, assessing component interdependencies, and determining component weightage for optimal functionality and cost-effectiveness.
Results: The DEMATEL and GP approach proved effective in optimizing the product family structure for weather radar systems. Key results include the identification and prioritization of variety indicators, evaluation of component interdependencies, and determination of component weightage, resulting in a more precise and operational design.
Conclusions: The proposed model for weather radar variety enhances customer satisfaction, meets market demands, and addresses the challenges of dynamic customer needs. This methodology offers valuable insights into managing product variety and complexity, enabling designers to quickly adapt to evolving customer requirements.
Trap Catches of Bark Beetle Predators Unaffected by the Ips Pheromone Lanierone in Southeastern United States1
Authors: Miller D.R. , Asaro C. 
Published: July 2024

Abstract
In 2003–2004, a trapping study with multiple-funnel traps was conducted in Florida, Georgia, North Carolina, and Louisiana to evaluate the effects of the bark beetle pheromones ipsenol, ipsdienol, and lanierone on catches of bark beetles and associated species. The results on bark and ambrosia beetles have been reported previously. Herein, we report on the responses of predators in the same study. Ipsenol and/or ipsdienol attracted several species of coleopteran predators: Enoclerus nigripes (Say) (Cleridae); Temnoscheila virescens (F.) (Trogossitidae); Lasconotus species (Zopheridae); Corticeus species (Tenebrionidae); and Platysoma attenuatum LeConte, Platysoma cylindricum (Paykull), and Platysoma parallelum (Say) (Histeridae). Lanierone was not attractive alone, nor did it enhance trap catches of any of these predator species. In Georgia, lanierone interrupted attraction of E. nigripes to traps baited with ipsenol. We highlight that the use of lanierone appears to be restricted to three Ips species in the subgenus Ips (Bonips). Further research on the general role of lanierone in the chemical ecology of bark beetles and predators should be conducted over a broad geographic range.
Chemical Composition and Insecticidal Activity of Essential Oil from Syzygium aromaticum (Myrtaceae) against the Sawtoothed Grain Beetle Oryzaephilus surinamensis (Coleoptera: Silvanidae)1
Authors: Wanna Ruchuon , Kunlanit Benjapon , Bunphan Darika , Khaengkhan Phirayot , Khaengkhan Parinda , Bozdoğan Hakan 
Published: July 2024

Abstract
Utilizing essential oils extracted from specific herbal plants offers an intriguing alternative to synthetic insecticides, which are known for their harmful effects on both consumers and the environment, in preventing the devastation caused by the sawtoothed grain beetle, Oryzaephilus surinamensis L. (Coleoptera: Silvanidae). This study aimed to explore the chemical composition and insecticidal activities of essential oil derived from Syzygium aromaticum (L.) Merrill & L.M. Perry against adults of O. surinamensis. The research involved assessing the chemical compound of the essential oil from the flower buds of S. aromaticum, evaluating its fumigant toxicity and its repellent effect on O. surinamensis adults through vapor-phase testing conducted in laboratory conditions at 30°C ± 5°C and relative humidity of 70% ± 5%. The experimental design used a completely randomized design with four replications and six concentrations (0, 10, 20, 30, 40, and 50 μl/l of air). A total of nine chemical constituents was identified, with eugenol (90.15%) emerging as the primary compound in S. aromaticum essential oil. The fumigation toxicity (50% lethal concentration) assessments on adult O. surinamensis at 24, 48, and 72 h revealed values of 9.70, 6.58, and 4.37 μl/l of air, respectively. Over the 24- to 120-h test period, the application of S. aromaticum essential oil at 50 μl/l of air resulted in the highest adult mortality among O. surinamensis. Notably, at a concentration of 40 μl/l of air, the essential oil of S. aromaticum demonstrated a fumigation efficiency of 90–100% at both 24 and 72 h, showing no significant difference compared with a concentration 50 μl/l of air. These findings highlight the potential of S. aromaticum essential oil as an effective insecticide for controlling O. surinamensis populations in agricultural storage.
Risk Factors of Postpartum Depression Among Iranian Women: A Systematic Review and Meta-analysis
Authors: Seyed-Nezhad Maryam , Manzouri Leila , Bazarganipour Fatemeh , Shokohiasl Hajar , Moradi-Joo Mohammad 
Published: July 2024

BACKGROUND:Postpartum depression (PPD) is an important and prevalent disorder that can have short-term and long-term adverse effects on the mother, child, and family. This meta-analysis was conducted with the aim of investigating factors related to PPD in Iran.METHODS:This systematic review and meta-analysis reviewed observational studies in Iran. Four Persian language databases (Magiran, IranDoc, ISC, and SID) and four English language databases (ScienceDirect, Scopus, PubMed, and Web of Science) were searched from their inception to September 20, 2023. Google Scholar search engine was used to find relevant sources and complete the search coverage. The process of searching and selecting studies was drawn using the Preferred Reporting Items for Systematic reviews and Meta-Analysis diagram. The strength of the association was summarized using the odds ratio (OR) with 95% confidence intervals (CIs). We used RevMan 5.4 software to analyze the data after extraction.RESULTS:A total of 28 studies involving 11,784 participants were included. The meta-analysis showed that cesarean section (OR = 0.77, 95% CI [0.60, 0.98]), history of abortion (OR = 1.48, 95% CI [1.14, 1.92]), unwanted pregnancy (OR = 0.58, 95% CI [0.45, 0.76]), formula feeding (OR = 0.50, 95% CI [0.39, 0.65]), diploma and less education (OR = 1.27, 95% CI [1.08, 1.48]), neonatal hospitalization (OR = 1.77, 95% CI [1.13, 2.76]), more than two deliveries (OR = 0.76, 95% CI [0.67, 0.86]), and low and moderate socioeconomic status (OR = 1.77, 95% CI [1.34, 2.34]) have a significant effect on PPD. Satisfaction of the newborn gender (OR = 0.88, 95% CI [0.58, 1.33]), employment (OR = 1.16, 95% CI [0.97, 1.40]), age (OR = 0.89, 95% CI [0.58, 1.39]), previous depression (OR = 1.76, 95% CI [0.88, 3.50]), and gender of the newborn (OR = 0.82, 95% CI [0.42, 1.60]) did not have a significant effect on PPD.CONCLUSION:The results of this study showed that many factors influence PPD. Most of these factors can be identified during pregnancy, which shows the importance of screening during pregnancy. Therefore, it is necessary to design and use screening tools to identify predisposing variables for PPD according to the social–cultural characteristics of different populations.
Beyond Tobacco: Genomic Disparities in Lung Cancer Between Smokers and Never-Smokers
Authors: Garrido Javiera , Bernal Yanara , González Evelin , Blanco Alejandro , Sepúlveda-Hermosilla Gonzalo , Freire Matías , Oróstica Karen , Rivas Solange , Marcelain Katherine , Owen Gareth , Ibañez Carolina , Corvalan Alejandro , Garrido Marcelo , Assar Rodrigo , Lizana Rodrigo , Cáceres-Molina Javier , Ampuero Diego , Ramos Liliana , Pérez Paola , Aren Osvaldo , Chernilo Sara , Fernández Cristina , Spencer María Loreto , Aguila Jacqueline Flores , Dossetto Giuliano Bernal , Olea Mónica Ahumada , Rasse Germán , Sánchez Carolina , Amorim Maria Galli , Bartelli Thais F. , Nunes Diana Noronha , Dias-Neto Emmanuel , Armisén Ricardo , Freitas Helano C. 
Published: July 2024

Abstract

Background
Tobacco use is one of the main risk factors for Lung Cancer (LC) development. However, about 10–20% of those diagnosed with the disease are never-smokers. For Non-Small Cell Lung Cancer (NSCLC) there are clear differences in both the clinical presentation and the tumor genomic profiles between smokers and never-smokers. For example, the Lung Adenocarcinoma (LUAD) histological subtype in never-smokers is predominately found in young women of European, North American, and Asian descent. While the clinical presentation and tumor genomic profiles of smokers have been widely examined, never-smokers are usually underrepresented, especially those of a Latin American (LA) background. In this work, we characterize, for the first time, the difference in the genomic profiles between smokers and never-smokers LC patients from Chile.
Methods
We conduct a comparison by smoking status in the frequencies of genomic alterations (GAs) including somatic mutations and structural variants (fusions) in a total of 10 clinically relevant genes, including the eight most common actionable genes for LC (EGFR, KRAS, ALK, MET, BRAF, RET, ERBB2, and ROS1) and two established driver genes for malignancies other than LC (PI3KCA and MAP2K1). Study participants were grouped as either smokers (current and former, n = 473) or never-smokers (n = 200) according to self-report tobacco use at enrollment.
Results
Our findings indicate a higher overall GA frequency for never-smokers compared to smokers (58 vs. 45.7, p-value < 0.01) with the genes EGFR, KRAS, and PIK3CA displaying the highest prevalence while ERBB2, RET, and ROS1 the lowest. Never-smokers present higher frequencies in seven out of the 10 genes; however, smokers harbor a more complex genomic profile. The clearest differences between groups are seen for EGFR (15.6 vs. 21.5, p-value:<0.01), PIK3CA (6.8 vs 9.5) and ALK (3.2 vs 7.5) in favor of never-smokers, and KRAS (16.3 vs. 11.5) and MAP2K1 (6.6 vs. 3.5) in favor of smokers. Alterations in these genes are comprised almost exclusively by somatic mutations in EGFR and mainly by fusions in ALK, and only by mutations in PIK3CA, KRAS and MAP2K1.
Conclusions
We found clear differences in the genomic landscape by smoking status in LUAD patients from Chile, with potential implications for clinical management in these limited-resource settings.
Parent-Child Communication and Educational Anxiety: A Longitudinal Analysis Based on the Common Fate Model
Authors: Gao Fengqiang , Xu Chunze , Qing Lv , Zhao Yufei , Han Lei 
Published: July 2024

Abstract

In the study of family relationships, the Common Fate Model (CFM) is a widely used and reliable model that is able to better explain the inherent patterns of interactions that exist in the dichotomous level. Based on the Common Fate Model, this study explored the influence of parent-child communication quality on parental education anxiety, and at the same time deeply analyzed the mediating role of parent-child trust relationship between the two. The study used the questionnaire method to select fathers and mothers from junior high schools in Jinan City to participate in the research by using stratified cluster sampling, collected data in two time periods (T1 and T2, with an interval of one year), and finally analyzed the data from the Parent-Child Communication Quality Questionnaire (T1), the Educational Anxiety Questionnaire (T2), and the Parent-Child Trusting Relationship Questionnaire (T2) from 910 fathers and mothers in 495 families. The results found that (1) based on the Common Fate Model, parent-child communication quality negatively predicted parental educational anxiety; (2) parent-child communication quality positively predicted parent-child trust relationship; (3) parent-child trust relationship negatively predicted parental educational anxiety; and (4) parent-child trust relationship mediated parent-child communication quality and educational anxiety. In conclusion, based on the Common Fate Model, this paper explores the mediating effect of the parent-child trust relationship between communication quality and parental educational anxiety to provide some theoretical support for alleviating parental educational anxiety.
Influence of H3K9 Methylation on Gene Mutation Rates: Advancing Epigenetic Research with Controlled Experimental Design
Authors: Abdalla Ola , Walker Cameron 
Published: July 2024

Abstract

Mutations drive genetic variation, fueling both oncogenesis and species evolution. The mutation rate varies across the genome, potentially influenced by chromatin organization through histone modifications and other factors. However, the precise relationship between chromatin structure and mutation rate remains poorly understood and needs further investigation. One such modification, the methylation of histone H3 at lysine 9 (H3K9me), is known to form heterochromatin and repress transcription in euchromatin, thereby maintaining genome stability essential for organism survival. This study aimed to elucidate the effect of H3K9 methylation, in isolation from other histone markers, on the mutation rate in fission yeast. Employing fluctuation assays and statistical analysis, our innovative methodology estimates the mutation rates of a single gene under two different conditions within a single experiment using an isogenic clone. Our findings reveal that H3K9me markers significantly increase the phenotypic mutation rate of the same gene. For prospective researchers, this study introduces a new experimental approach that offers unprecedented accuracy in gene analysis, with implications for both genetic research and epigenetic therapy.
Quality of Cerebral Palsy-Related Videos on Chinese Social Media Platforms
Authors: He Wenjie , Tang Dongning , Jin Ya , Zhang Wenyan , Kang Yunyun , Qing Xia 
Published: July 2024

Abstract

Background
A significant research gap exists in evaluating the prevalence and quality of Chinese videos depicting CP on domestic social media platforms. In contrast to studies that focus on online video content concerning CP on YouTube, CP videos on YouTube are largely inaccessible to average citizens in mainland China. This disparity underscores the need for further investigation into the availability and nature of CP videos specifically on Chinese social media platforms.
Methods
The present cross-sectional study examined 344 videos about CP from popular Chinese social media platforms, including TikTok, Kwai, Weibo, Bilibili, and RED. The analysis of these videos involved a detailed assessment of their sources, content, and characteristics. Additionally, quantitative scoring tools such as Journal of the American Medical Association (JAMA) Benchmarks, Global Quality Score (GQS), and DISCERN were utilized to evaluate video quality. Furthermore, the potential relationship between video quality and various attributes such as duration, number of likes, and comments was explored and their impact on the quality of information presented in the videos was analyzed.
Results
The average duration of the 344 videos was 92.12 seconds (SD 105.69). CP rehabilitation training videos comprised 45.64% of the total, followed by expert-contributed videos at 40.70%. Mean scores for JAMA, GQS, and DISCERN were 1.62 (SD 0.60), 2.05 (SD 0.99), and 1.26 (SD 1.26) respectively. RED had the lowest average scores. Videos focusing on disease knowledge scored highest on JAMA and GQS scales. Experts achieved significantly higher GQS and DISCERN scores compared to health-related institutions and amateurs. Spearman correlation analysis revealed a strong positive correlation between likes and comments (r = 0.87, P < .001).
Conclusion
Enhancing the management of medical content is crucial to address the compromised reliability of Chinese online short videos providing information to families of CP patients. Improving content professionalism and accuracy ensures users access genuinely valuable information.
Valvular Heart Disease And Associated Factors Among Adult Known Cardiac Patients In A Tertiary Hospital In Ethiopia
Authors: Barata Tagese Yakob , Belay Eshetu , Yakob Begidu , Abraham Awoke , Dawit Desalegn , Israel Esknider 
Published: July 2024

Abstract

Background
Valvular heart disease (VHD) is the leading cause of mortality and morbidity, followed by coronary artery disease, hypertension, and heart failure. In Ethiopia, VHD accounts for 40.5% of cardiovascular diseases. However, existing studies from Ethiopia have focused only on the rheumatic cause of VHD. Therefore, it is imperative to assess the burden of VHD risk factors. This study aimed to assess the burden of valvular heart disease (VHD) and its associated factors among adult known cardiac patients in at Saint Paul Hospital Millennium Medical College in Ethiopia.
Methods
A facility-based retrospective cross-sectional study was carried out on 422 participants from January 1 to May 30, 2023. Secondary data were extracted from patient records. Finally, sample selection was performed using a simple random system. The data were entered and cleaned by Epi-data 4.6.0.2 and exported to STATA version 14 for analysis. Descriptive characteristics such as frequency, mean, median and percentage were recorded. Model goodness-of-fit was checked by the Hosmer and Lemeshow test (0.272). Logistic regression using a p value of < 0.05 at the 95% CI was used for measuring the associations of variables concerning their AORs.
Results
An overall response rate of 98.8% was achieved with a total of 417 study participants. The mean age (± SD) of the participants was 50.42 (± 0.62) years. The burden of valvular heart disease among the population studied was 73 (17.06%) (95% CI, 14.13–21.47). The burden of VHD was greater for participants from urban areas than for those from urban areas. Rheumatic heart disease (35.90%) was the most commonly reported etiology causing valvular lesions, followed by infective endocarditis (30.77%). Family history of cardiovascular disease (AOR = 3.56, 95% CI: 1.76–7.12), history of hypertension (AOR = 2.83, 95% CI: 1.48–5.41), thyroid disease (AOR = 3.59, 95% CI: 1.51–8.56), and history of adult malnutrition (AOR = 4.93, 95% CI: 2.04–10.14) are independent predictors of valvular heart disease.
Conclusion
The burden of valvular heart disease (VHD) was high in the population studied. A family history of cardiovascular disease, hypertension, and thyroid disease and the presence of adult malnutrition were significantly associated with depression in patients living with valvular heart disease. Early screening of valvular heart disease by echocardiography among cardiac patients should be strengthened in all public health facilities and all private facilities on board.
Associations of SGLT-2i with Cardiorenal Outcomes Among Diabetics with Prostate Cancer on Hormone Therapy
Authors: Koutroumpakis Efstratios , Patel Rushin , Khadke Sumanth , Bedrosian Aram , Kumar Ashish , Kong Yixin , Connell Brendan , Upadhyay Jagriti , Dani Sourbha S. , Hahn Andrew W. , Logothetis Christopher J. , Al-Kindi Sadeer , Butler Javed , Nohria Anju , Ganatra Sarju , Deswal Anita 
Published: July 2024

Abstract

Background
Studies have reported associations between prostate cancer, type II diabetes mellitus (T2DM) and cardiovascular disease in the context of treatment with hormone therapy (HT). This study aimed to assess the role of Sodium-Glucose Cotransporter-2 Inhibitors (SGLT2i) in preventing adverse cardiovascular and renal outcomes in diabetics with prostate cancer.
Methods
Patients ≥ 18 years of age with T2DM and prostate cancer who received HT between August 1, 2013, and August 31, 2021, were identified using the TriNetX research network. Patients were divided into two cohorts based on treatment with SGLT2i or alternative antidiabetic therapies. The primary outcome was the composite of all-cause mortality, new onset heart failure (HF), acute myocardial infarction (MI), and peripheral artery disease over two years from HT initiation.
Results
After propensity score matching, 2,155 patients remained in each cohort. The primary composite outcome occurred in 218 patients (16.1%) in the SGLT2i cohort versus 355 patients (26.3%) in the non-SGLT2i cohort (HR 0.689, 95% CI 0.582–0.816; p < 0.001). Furthermore, SGLT2i were associated with significantly lower odds of HF, HF exacerbation, peripheral artery disease, atrial fibrillation/flutter, cardiac arrest, need for renal replacement therapy, overall emergency room visits/hospitalizations and all-cause mortality.
Conclusions
Use of SGLT2i for the treatment of T2DM among patients with prostate cancer on HT is associated with favorable cardiovascular, renal and all-cause mortality outcomes. This observation supports the hypothesis that a therapeutically relevant link exists between HT and cardiovascular disease in the context of prostate cancer.