bluuebunny/crossref_metadata_2025_split huggingface dataset:
New species records for butterflies (Lepidoptera) on Herschel Island, Yukon, Canada, with notes on natural history
Authors: Leung Maria C. , Reid Donald G. 
Published: March 2013

AbstractComparisons of past and current butterfly species distributions are being used to gauge the effects of climatic change in various parts of the world. Historic butterfly records from Herschel Island, Yukon, Canada, presented an opportunity to do such a comparison in an Arctic tundra region known to have a diverse butterfly fauna. We compared historic species records (1916–1983) with newly collected ones (2007–2009) to assess possible changes in species distributions. Of the 21 species documented for Herschel Island, six were newly found and two were not reconfirmed. We postulate that warmer temperatures facilitated the apparent northerly range expansions of several species by making butterfly flight and dispersal possible. This is supported by interannual comparisons on a smaller time scale, 2007–2009. During this period, we observed accelerated butterfly phenology and higher relative abundance of butterflies associated with earlier snowmelt and with earlier and more intense early summer heating.
A Case-Control Study of Esomeprazole plus Rebamipide vs. Omeprazole plus Rebamipide on Post-ESD Gastric Ulcers
Authors: Bunno Maki , Gouda Kyosuke , Yamahara Kunihiro , Kawaguchi Masanori 
Published: March 2013

Objectives Endoscopic submucosal dissection (ESD) is useful for treating gastric tumors. Several trials have shown the efficacy of 4 or 8 weeks of proton pump inhibitor (PPI) administration for post-ESD ulcers. However, if the size of the post-ESD ulcer is larger than predicted, PPI administration alone might not be sufficient for the ulcer to heal within 4 weeks. There is no report about the efficacy of post-ESD gastric ulcers by esomeprazole. We examined retrospectively the efficacy of a combination therapy of esomeprazole plus rebamipide, a mucosal-protective antiulcer drug, on the acceleration of post-ESD ulcer healing comparing with omeprazole plus rebamipide. Methods We reviewed the medical records of patients who underwent ESD for gastric neoplasia. We conducted a case-control study to compare the healing rates within 4 weeks effected by esomeprazole plus rebamipide (group E) and omeprazole plus rebamipide (group O). The sizes of the artificial ulcers were divided into normal-sized or large-sized. Results The baseline characteristics did not differ significantly between the two groups except age and sex. Stage S1 disease was observed in 27.6% and 38.7% of patients after 4 weeks of treatment in the group E and O, respectively. In large-sized artificial ulcers, the healing rate of stage S1 in group E is significantly higher than that in group O in 4 weeks.(25% VS 0%: P = 0.02) Conclusions The safety and efficacy profiles of esomeprazole plus rebamipide and omeprazole and rebamipide are similar for the treatment of ESD-induced ulcers. In large-sized ulcers, esomeprazole plus rebamipide promotes ulcer healing.
Looking after the left-behind families of overseas Filipino workers: The Philippine experience
Authors: Asis Maruja M.B. 
Published: March 2013

AbstractArticle 16.3 of the Universal Declaration of Human Rights states that “[t]he family is the
natural and fundamental group unit of society and is entitled to protection by society and the
State.” This task has become a lot more challenging in the age of migration, particularly under a
migration regime wherein only workers are allowed admission to another country under specific
terms while their family members are left in the countries of origin. To date, the protection
and promotion of the welfare of left-behind families is assumed to be the sole responsibility of
countries of origin. Based on the experience of the Philippines as an origin country, this paper
outlines the impact of international migration on the families of migrants; describes institutions,
programs and services developed by the government and other stakeholders to promote their
protection and welfare; and concludes with recommendations for transnational cooperation to
ensure that the families of migrant workers are not left behind as participants in policy, research
and advocacy.
The Idea of Labyrinth (Migong) in Chinese Building Tradition
Authors: Zou Hui 
Published: March 2013

Abstract
The concept of labyrinth as a design idea is prevalent throughout the history of Western architecture. In the late-eighteenth century when the Western Jesuits built a labyrinth as a part of a "Western-like" garden within the Chinese imperial garden Yuanming Yuan, the labyrinth appeared exotic and enjoyable for the Chinese. This essay explores the idea of labyrinth in Chinese building tradition through analyzing the historical literature of imperial buildings, imperial mausoleums, and gardens. The analyzed cases of labyrinth include the Perplexing Multistoried Buildings (Milou), the thirteen Ming imperial mausoleums, the imperial gardens imitating fairylands, and the rockery hill in a literati garden. The essay relates the discovered idea of labyrinth to Confucian and Chinese cosmological aesthetics. The revealed perception of labyrinth facilitates the understanding of the encounter between Western and Chinese concepts of labyrinth in early modernity. In addition, it aids in the development of a comparative perspective on the meaning of labyrinth in the art of building.
Long-term Effect of Aesthetic Education on Visual Awareness
Authors: Funch Bjarne Sode , Krøyer Louise Lidang , Roald Tone , Wildt Elisabeth 
Published: March 2013

Abstract
A class of fourth-graders (nine-to-ten-year-olds) was taught art appreciation one day a week during an entire school year. Three years later their performance in visual awareness was tested and compared to the performance of pupils of the same age from another class who had not received any particular education in art appreciation. The results show that the young people who participated in the educational program performed notably better in visual awareness than those who did not.
Development and Confirmatory Factor Analysis of the Non‐Violent and Violent Offending Behavior Scale (NVOBS)
Authors: Thornton Abigail J.V. , Graham‐Kevan Nicola , Archer John 
Published: March 2013

AbstractThe purpose of this research was to develop a psychometrically sound measure of violent and non‐violent offending, suitable for both male and female participants in general (non‐forensic) samples. Potential items were selected from existing measures. A sample of 653 British university students completed all items, and their responses were analyzed using exploratory factor analysis and validated with confirmatory factor analysis. There were five separate factors (general violence, drug‐related offenses, partner violence, theft, and criminal damage), which were confirmed with acceptable fit indices. The five‐factor model applied to both males and females. Each subscale demonstrated good internal consistency, with alphas for each factor ranging from moderate to good. This new measure is a potentially valuable research tool for investigating people's involvement in violent and non‐violent offending. The importance of examining the psychometric properties of scales, and confirming the category groupings using CFA of the items is outlined. Aggr. Behav. 39 :171‐181, 2013. © 2013 Wiley Periodicals, Inc.
Soft Iron/Silicon Composite Tubes for Magnetic Peristaltic Pumping: Frequency‐Dependent Pressure and Volume Flow
Authors: Fuhrer Roland , Schumacher Christoph M. , Zeltner Martin , Stark Wendelin J. 
Published: March 2013

AbstractThe combination of force and flexibility enables controlled and soft movements. In sharp contrast, presently used machines are solid and mostly based on stiff driveshafts or cog wheels. Magnetic elastomers are realized through dispersion of small particles in polymer matrices and have attracted significant interest as soft actuators for controlled movement or conveying and are particularly attractive candidates for magnetic pump applications. At present, low magnetic particle loading and thus limited actuator strength have restricted the application of such materials. Here, the direct incorporation of metal microparticles into a very soft and flexible silicone and its application as an ultra‐flexible, yet strong magnetic tube, is described. Because metals have a far higher saturation magnetization and higher density than oxides, the resulting increased force/volume ratio afforded significantly stronger magnetic actuators with high mechanical stability, flexibility, and shape memory. Elliptical inner diameter shape of the tubing allowed a very efficient contraction of the tube by applying an external magnetic field. The combination of magnetic silicone tubes and a magnetic field generating device results in a magnetic peristaltic pump.
Buckling‐Based Strong Dry Adhesives Via Interlocking
Authors: Chen Chi‐Mon , Chiang Chang‐Lung , Lai Chien‐Lin , Xie Tao , Yang Shu 
Published: March 2013

AbstractHigh‐aspect‐ratio shape‐memory polymer (SMP) pillar arrays are investigated as a new type of dry adhesive based on buckling and interlocking mechanism. When two identical SMP pillar arrays are engaged at 80 °C, above the glass transition temperature at a preload larger than the critical buckling threshold, the pillars are deformed and become interweaved and/or indented with each other. After cooling to room temperature, strong pull‐off forces are observed in the normal and shear directions, both of which are much larger than those from pillar‐to‐flat surface and flat‐to‐flat surface contact. From finite element anaylsis (FEA) and comparison of measured and calculated adhesion values using different contact mechanics models, it is shown that interweaved pillars are the main source that contributes to the pillar‐to‐pillar adhesion and the indented pillars set the lower limit, whereas the probability of interdigitation is very low. Further, it is found that interweaved pillars are primarily responsible for the decreased adhesion strength and increased anisotropy when the pillar spacing became larger. Finally, it is shown that the bonded pillars can be easily separated after reheating to 80 °C due to significant drop of modulus of SMPs.
Interstitial Duplication of 2q32.1–q33.3 in a Patient With Epilepsy, Developmental Delay, and Autistic Behavior
Authors: Usui Daisuke , Shimada Shino , Shimojima Keiko , Sugawara Midori , Kawasaki Hajime , Shigematu Hideo , Takahashi Yukitoshi , Inoue Yushi , Imai Katsumi , Yamamoto Toshiyuki 
Published: March 2013

AbstractDuplications of the 2q33 region are rare; to date, only 13 patients have been reported to have this chromosomal abnormality. The reported duplications are of varying size, and the patients shared developmental delay and minor dysmorphic findings. In this study, we identified a duplication of 2q32.1–q33.3 in a patient with psychomotor developmental delay, epilepsy, and autistic behavior. The duplicated region of this patient was reciprocal to the 2q32–q33 deletion syndrome. Chromosomal microarray testing confirmed the 19.5 Mb of duplication that includes over 100 genes, some of which could have functional relevance to the neurological features of this patient. The SATB homeobox 2 gene (SATB2)—the primary gene responsible for the 2q32–q33 deletion syndrome—may be one of them, because of its expression in the cortical projection neurons of the developing brain. The duplication of the potassium channel tetramerisation domain‐containing 18 gene (KCTD18) and the ADAM metallopeptidase domain 23 gene (ADAM23) may also contribute to the phenotype. FISH analysis confirmed a tandem configuration of the duplicated segments. This result is in agreement with our previous study, in which we observed that duplicated segments as interstitial duplications are generally inserted in the tandem configuration. © 2013 Wiley Periodicals, Inc.
Simpson–Golabi–Behmel Syndrome Type 1 and Hepatoblastoma in a Patient With a Novel Exon 2–4 Duplication of the GPC3 Gene
Authors: Mateos María Elena , Beyer Katrin , López‐Laso Eduardo , Siles Juan López , Pérez‐Navero Juan Luis , Peña María José , Guzmán Juana , Matas Juliana 
Published: March 2013

AbstractMutations in the gene encoding glypican (GPC) 3 appear to be responsible for most cases of Simpson–Golabi–Behmel syndrome type 1. Duplication of the GPC4 gene has also been associated to this syndrome; however, no duplications involving GPC3 have been related. We describe a family that harbors a novel exon 2–4 duplication event leading to a truncating germline mutation of the GPC3 gene that, to our knowledge, has not been previously reported. GPC3 transcripts that carry this duplication bear non‐functional proteins making its pathogenic role highly probable. The absence of a functional GPC3 may alter the normal differentiation of embryonal mesodermal tissues predisposing to the development of embryonal tumors, as the index case studied who developed a hepatoblastoma at age 9 months. © 2013 Wiley Periodicals, Inc.
Trilateral Retinoblastoma in a Patient With Peutz–Jeghers Syndrome
Authors: Raizis Anthony M. , Van Mater David , Aaltonen Lauri A. , Lohmann Dietmar , Cheale Michelle S. , Bickley Vivienne M. , George Peter M. , Zhou Yaolin , Rosoff Philip M. 
Published: March 2013

AbstractGermline loss of function mutations in tumor suppressor genes RB1 and LKB1/STK11 are associated with the autosomal dominant cancer predisposing syndromes familial retinoblastoma and Peutz–Jeghers syndrome (PJS), respectively. We present a rare case of a young woman with trilateral retinoblastoma diagnosed as an infant who survived and was then diagnosed with PJS as a teenager. There was no family history of either disorder. Analysis of the LKB1/STK11 gene sequence identified a germline frameshift mutation (c.107del) leading to a nonsense mutation near the N‐terminus of the protein, confirming a clinical diagnosis of Peutz–Jeghers syndrome. Extensive RB1 gene analysis failed to detect germline mutations or deletions, and immunohistochemical analysis of her ocular tumors demonstrated nuclear staining of immunoreactive pRB. This result suggests that the RB1 gene is intact. We estimate the chance of trilateral retinoblastoma and PJS occurring in the same individual at approximately 1 in 134 billion live births, and we discuss the possibility that this case could be explained by a putative modifier of pRB action that is associated with the LKB1/STK11 pathway. © 2013 Wiley Periodicals, Inc.
Replication of Genome Wide Association Identified Candidate Genes Confirm the Role of Common and Rare Variants inPAX7andVAX1in the Etiology of Nonsyndromic CL(P)
Authors: Butali Azeez , Suzuki Satoshi , Cooper Margaret E. , Mansilla Adela M. , Cuenco Karen , Leslie Elizabeth J. , Suzuki Yasushi , Niimi Teruyuki , Yamamoto Masahiko , Ayanga Gongorjav , Erkhembaatar Tudevdorj , Furukawa Hiroo , Fujiwawa Kumiko , Imura Hideto , Petrin Aline L. , Natsume Nagato , Beaty Terri H. , Marazita Mary L. , Murray Jeffery C. 
Published: March 2013

AbstractFollowing recent genome wide association studies (GWAS), significant genetic associations have been identified for several genes with nonsyndromic cleft lip with or without cleft palate (CL(P)). To replicate two of these GWAS signals, we investigated the role of common and rare variants in thePAX7andVAX1genes. TaqMan genotyping was carried out for SNPs inVAX1andPAX7and transmission disequilibrium test (TDT) was performed to test for linkage and association in each population. Direct sequencing in and around thePAX7andVAX1genes in 1,326 individuals of European and Asian ancestry was done. The TDT analysis showed strong associations with markers inVAX1(rs7078160,P = 2.7E−06 and rs475202,P = 0.0002) in a combined sample of Mongolian and Japanese CL(P) case–parent triads. Analyses using parent‐of‐origin effects showed significant excess transmission of the minor allele from both parents with the effect in the mothers (P = 6.5E−05, OR (transmission) = 1.91) more striking than in the fathers (P = 0.004, OR (transmission) = 1.67) forVAX1marker rs7078160 in the combined Mongolian and Japanese samples when all cleft types were combined. The rs6659735 trinucleotide marker inPAX7was significantly associated with all the US cleft groups combined (P = 0.007 in all clefts andP = 0.02 in CL(P)). Eight rare missense mutations found inPAX7and two rare missense mutations inVAX1. Our study replicated previous GWAS findings for markers inVAX1in the Asian population, and identified rare variants inPAX7andVAX1that may contribute to the etiology of CL(P). Determining the role of rare variants clearly warrants further investigation. © 2013 Wiley Periodicals, Inc.
Evaluation of Tibial Osteopathy Occurrence in Neurofibromatosis Type 1 Italian Patients
Authors: Morcaldi Guido , Clementi Maurizio , Lama Giuliana , Gabrielli Orazio , Vannelli Silvia , Virdis Raffaele , Vivarelli Rossella , Boero Silvio , Bonioli Eugenio 
Published: March 2013

AbstractNeurofibromatosis Type 1 (NF1) is a common autosomal dominant disorder characterized by high penetrance, widely variable expressivity and occurrence of specific skeletal changes such as tibial osteopathy (TO). We collected data on patients referred to the Italian Neurofibromatosis Study Group in order to compare clinical features between 49 NF1 patients with TO, and 98 age‐matched NF1 patients without TO, and to determine whether the presence of TO is associated with a different risk of developing the typical NF1 complications. We assessed both groups for: age at diagnosis of NF1, gender distribution, family history, gender inheritance, presence of scoliosis, sphenoid wing osteopathy, other skeletal abnormalities, macrocrania, hydrocephalus, plexiform neurofibromas, tumors, optic pathway gliomas, T2H (high‐signal intensity areas on T2 weighted brain MRI), epilepsy, headache, mental retardation, cardiovascular malformations, and Noonan phenotype. Patients of both groups were subdivided by gender and re‐evaluated for these items. Statistical comparison was carried out between the two groups of patients for each feature. We collected data on type of treatment and on the clinical conditions of NF1‐TO patients after follow‐up. Patient's age at NF1 diagnosis was significantly younger in NF1‐TO subjects compared with NF1 subjects without TO, and the incidence of T2H was significantly reduced in NF1‐TO males compared with NF1 males without TO. The presence of TO does not imply that there is an increased risk of developing typical complications of NF1 (e.g., optic pathway glioma, plexiform neurofibroma, etc.), however, it does allow us to make an earlier diagnosis of NF1. © 2013 Wiley Periodicals, Inc.
A novel low‐energy hybrid process for the removal of organic contaminants in ultrapure water systems
Authors: Sun T. , Chen K. 
Published: March 2013

ABSTRACTTo achieve the goal of implementation of low‐energy and low‐chemical usage for trace organic compound removal, the hybrid oxidation/adsorption purification system using nitrogen‐doped titanium dioxide catalytic oxidation followed by activated carbon adsorption was proposed in this paper. When isopropyl alcohol, ethylene glycol, and urea were selected as model components, superior oxidation effects were achieved by combination of nitrogen‐doped titanium dioxide with 254 nm UV unit than by traditional high‐energy‐consumed 185 nm UV unit, which indicated such configuration would be an ideal candidate to replace the current high‐energy‐consumed UV unit. By incorporating this new configuration into the semiconductor wastewater recycling system, the granule‐activated carbon bed adsorption efficiency for total organic carbon was compared with the granule‐activated carbon adsorption efficiency for total organic carbon in traditional purification system, where the 185 nm UV lamp was used as oxidation unit. The experimental results showed that the hybrid low energy consumption catalytic oxidation/adsorption system had higher efficiency than the traditional high‐energy‐consumed oxidation/adsorption system for trace organic compound removal. This was because the radicals formed in the UV oxidation process reacted with the organic compounds adsorbed on the activated carbon and regenerated the adsorption sites. This self‐cleaning mechanism effectively extended the lifetime of activated carbon bed and increased its adsorption capability. © 2013 Curtin University of Technology and John Wiley & Sons, Ltd.
Development and multiplexing of microsatellite loci for the near threatened freshwater mussel Potomida littoralis (Cuvier, 1798) using 454 sequencing
Authors: Froufe E. , Sobral C. , Teixeira A. , Lopes A. , Sousa R. , Varandas S. , Lopes‐Lima M. 
Published: March 2013

ABSTRACTThe Unionidae are among the most endangered fauna in the world and globally in decline. They are particularly vulnerable to habitat loss and fragmentation, susceptible to flow, pollution and climatic disturbances and introduction of invasive species. Despite their well‐recognized ecological and conservation importance, there is a surprising lack of genomic resources currently available for European species.The aim of this study was to develop and characterize microsatellites for the near threatened freshwater mussel,Potomida littoralisusing 454 sequencing.In order to improve genotyping throughput as well as cost‐effectiveness, two multiplex‐PCR reactions were designed to amplify 16 new loci. All the new 16 microsatellites were successfully combined in two multiplexed PCR with the number of alleles ranging from 2 to 25 per locus (with a mean of 10), confirming the utility of the new markers.The new genetic markers can therefore be used for studying the population genetic structure and evolution of this species, e.g. to examine current levels of genetic variability within and between populations and thus to contribute to conservation and management. Copyright © 2013 John Wiley & Sons, Ltd.
Understanding phenotypic responses to global change
Authors: Gangoso Laura , Márquez‐Ferrando Rocío , Ramírez Francisco , Gomez‐Mestre Ivan , Figuerola Jordi 
Published: March 2013

AbstractEditor's suggested further reading in BioEssays: Evolution in response to climate change: In pursuit of the missing evidence AbstractHow will fish that evolved at constant sub‐zero temperatures cope with global warming? Notothenioids as a case study Abstract
Dual‐color‐emitting green fluorescent protein from the sea cactus Cavernularia obesa and its use as a pH indicator for fluorescence microscopy
Authors: Ogoh Katsunori , Kinebuchi Takashi , Murai Mariko , Takahashi Takeo , Ohmiya Yoshihiro , Suzuki Hirobumi 
Published: March 2013

ABSTRACTWe isolated and characterized a green fluorescent protein (GFP) from the sea cactus Cavernularia obesa. This GFP exists as a dimer and has absorption maxima at 388 and 498 nm. Excitation at 388 nm leads to blue fluorescence (456 nm maximum) at pH 5 and below, and green fluorescence (507 nm maximum) at pH 7 and above, and the GFP is remarkably stable at pH 4. Excitation at 498 nm leads to green fluorescence (507 nm maximum) from pH 5 to pH 9. We introduced five amino acid substitutions so that this GFP formed monomers rather than dimers and then used this monomeric form to visualize intracellular pH change during the phagocytosis of living cells by use of fluorescence microscopy. The intracellular pH change is visualized by use of a simple long‐pass emission filter with single‐wavelength excitation, which is technically easier to use than dual‐emission fluorescent proteins that require dual‐wavelength excitation. Copyright © 2013 John Wiley & Sons, Ltd.