bluuebunny/crossref_metadata_2025_split huggingface dataset:
Metal‐Cation‐Directed Synthesis, Structures, and Optical Properties of Mo(W)/S(Se)/Ag Clusters: A Brief Overview
Authors: Li Jianghua , Zhang Jinfang , Humphrey Mark G. , Zhang Chi 
Published: November 2012

AbstractThis article provides a concise summary of recent research progress, including synthetic strategies, structural diversity, theoretical studies, and third‐order nonlinear optical (NLO) properties, on Mo(W)/S(Se)/Ag heterobimetallic clusters. It offers a preliminary analysis of their metal‐cation‐directed synthesis, structures, and the subtle interplay of structural–functional relationships. Furthermore, DFT was used to provide an insight into the electronic transitions and spectral characterization of these clusters. Recent trends and perspectives of these clusters as NLO materials are also described.
Explanation of Different Regioselectivities in the ortho‐Lithiation of Ferrocenyl(phenyl)methanamines
Authors: Almássy Ambroz , Škvorcová Andrea , Horváth Branislav , Bilčík Filip , Bariak Vladimír , Rakovský Erik , Šebesta Radovan 
Published: November 2012

AbstractDiastereoselective ortho‐lithiation of ferrocenes is a principal strategy for the synthesis of chiral ferrocene ligands. Dilithiation of (R)‐1‐(2‐bromophenyl)‐1‐ferrocenyl‐N,N‐dimethylmethanamine leads to a dilithium intermediate, which can be transformed to a Taniaphos ligand with (R,Rp)‐configuration. On the other hand, lithiation of (R)‐1‐phenyl‐1‐ferrocenyl‐N,N‐dimethylmethanamine affords a lithiated product with opposite configuration of the stereogenic plane. Presumably, the second lithium atom attached at the ortho‐position of the phenyl ring is responsible for this difference through the intramolecular multicenter arrangement involving both lithium atoms and their adjacent carbon atoms, the iron atom of the ferrocenyl moiety, and the nitrogen atom of the amino group. This hypothesis has been supported also by quantum chemical calculations.
Safety of thromboprophylaxis after oncologic head and neck surgery. Study of 1018 patients
Authors: Gavriel Haim , Thompson Evan , Kleid Stephen , Chan SorWay , Sizeland Andrew 
Published: November 2012

BackgroundDeep venous thrombosis (DVT) and pulmonary embolism (PE) are significantly reduced with appropriate use of thromboprophylaxis and scarcely evaluated in patients undergoing oncologic head and neck surgery (OHNS).MethodsA retrospective study on 1018 patients who underwent oncologic head and neck surgery. The records of patients with venous thromboembolism (VTE) or postoperative bleeding were reviewed for the cancer grading, management, previous known coagulopathy, anticoagulation, and general demographics.ResultsOf a total of 1018 patients undergoing oncologic head and neck surgery, 450 patients had no chemoprophylaxis and 568 received it. The rate of a VTE event in our cohort was 0%. Twelve patients presented with hematoma or bleeding from the surgical site, 11 in the group that received chemoprophylaxis (p = .006).ConclusionsOur analysis shows no benefit from chemoprophylaxis in oncologic head and neck surgery patients, with no VTE events. Our analysis shows higher rates of morbid side effects from using chemoprophylaxis, and we therefore conclude that chemoprophylaxis should not be routinely used. © 2012 Wiley Periodicals, Inc. Head Neck 35: 1410–1414, 2013
The effect of plaster (CaSO4·1/2H2O) on the compressive strength, self‐setting property, and in vitro bioactivity of silicate‐based bone cement
Authors: Liu Wenjuan , Wu Chengtie , Liu Weining , Zhai Wanyin , Chang Jiang 
Published: November 2012

AbstractBone cements have been widely used for orthopedic applications. Previous studies have shown that calcium silicon‐based bone cements (CSC) were injectable, bioactive, biodegradable, and mechanically strong in the long term, while their short‐term compressive strength was low and setting time was too long. On the other hand, plaster (CaSO4·1/2H2O, POP) sets quickly upon contact with water and has excellent short‐term compressive strength. The aim of this study is to prepare CSC/POP composite cements and investigate the effect of POP on the compressive strength, setting time, injectability, degradation, and in vitro bioactivity of the composite cements. The results have shown that POP content plays an important role to modulate the physicochemical property of CSC. The addition of POP into CSC significantly decreased the initial and final setting time and enhanced the short‐term compressive strength and degradation rate. The obtained composite cement with 30% POP has been found to possess optimal setting time and short‐term compressive strength. In addition, the prepared composite cements still maintain apatite‐mineralization ability in simulated body fluids and their ionic extracts have no significant cytotoxicity to L929 cells. The results suggested that the addition of POP into CSC is a viable method to improve their setting properties and short‐term compressive strength. The obtained composite cements with the optimized composition of 70% CSC and 30% POP could be potentially used for bone repair application. © 2012 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2013.
Corrosion behavior of novel Ti‐24Nb‐4Zr‐7.9Sn alloy for dental implant applications in vitro
Authors: Cheng Yicheng , Hu Jiang , Zhang Chunbao , Wang Zhongyi , Hao Yulin , Gao Bo 
Published: November 2012

AbstractTi‐24Nb‐4Zr‐7.9Sn (TNZS) alloy is a newly developed β‐titanium alloy considered suitable for dental implant applications due to its low elastic modulus and high strength. The aim of this study was to investigate the corrosion behavior of TNZS alloy through a static immersion test in various simulated physiological solutions, namely, artificial saliva, lactic acid solution, fluoridated saliva, and fluoridated acidified saliva for 7 days. The corrosion behavior of commercially pure titanium and Ti‐6Al‐4V alloy were also examined for comparison. The elemental release was measured with inductively coupled plasma mass spectroscopy, and the changes of alloy surface were observed with scanning electron microscopy (SEM). The test results showed that the quantity of each metal element released from TNZS alloy into fluoridated solutions was much higher than the solutions without fluoride ions. It was highest in fluoridated acidified saliva and lowest in artificial saliva (p < 0.01). The total elemental release from TNZS alloy was lower than commercially pure titanium and Ti‐6Al‐4V alloy in the same solution (p < 0.01). SEM micrographs indicated that TNZS alloy possessed better corrosion resistant performance. It can be concluded that fluoridated solutions have a negative influence on the corrosion behavior of TNZS alloy. Compared with commercially pure titanium and Ti‐6Al‐4V alloy, TNZS alloy demonstrates better corrosion resistance in various simulated physiological solutions, so it has greater potential for dental implant applications. © 2012 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2013.
Peak stress intensity factor governs crack propagation velocity in crosslinked ultrahigh‐molecular‐weight polyethylene
Authors: Sirimamilla Abhiram , Furmanski Jevan , Rimnac Clare 
Published: November 2012

AbstractUltrahigh‐molecular‐weight polyethylene (UHMWPE) has been successfully used as a bearing material in total joint replacement components. However, these bearing materials can fail as a result of in vivo static and cyclic loads. Crack propagation behavior in this material has been considered using the Paris relationship which relates fatigue crack growth rate, da/dN (mm/cycle) versus the stress intensity factor range, ΔK (Kmax − Kmin, MPa√m). However, recent work suggests that the crack propagation velocity of conventional UHMWPE is driven by the peak stress intensity (Kmax), not ΔK. The hypothesis of this study is that the crack propagation velocity of highly crosslinked and remelted UHMWPE is also driven by the peak stress intensity, Kmax, during cyclic loading. To test this hypothesis, two highly crosslinked (65 kGy and 100 kGy) and remelted UHMWPE materials were examined. Frequency, waveform, and R‐ratio were varied between test conditions to determine the governing factor for fatigue crack propagation. It was found that the crack propagation velocity in crosslinked UHMWPE is also driven by Kmax and not ΔK, and is dependent on loading waveform and frequency in a predictable quasistatic manner. This study supports that crack growth in crosslinked UHMWPE materials, even under cyclic loading conditions, can be described by a relationship between the velocity of crack growth, da/dt and the peak stress intensity, Kmax. The findings suggest that stable crack propagation can occur as a result of static loading only and this should be taken into consideration in design of UHMWPE total joint replacement components. © 2012 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 101B: 430–435, 2013.
Mitogen-activated protein kinase 2 regulates physiological and pathological bone turnover
Authors: Braun Tobias , Lepper Johannes , Ruiz Heiland Gisela , Hofstetter Willy , Siegrist Mark , Lezuo Patrick , Gaestel Matthias , Rumpler Monika , Thaler Roman , Klaushofer Klaus , Distler Jörg HW , Schett Georg , Zwerina Jochen 
Published: November 2012

Abstract
The objective of this study was to investigate the role of the serine-threonine kinase mitogen-activated protein kinase 2 (MK2) in bone homeostasis. Primary bone cell cultures from MK2+/+ and MK2–/– mice were assessed for osteoclast and osteoblast differentiation, bone resorption, and gene expression. Bone architecture of MK2+/+ and MK2–/– mice was investigated by micro–computed tomography and histomorphometry. Ovariectomy was performed in MK2+/+ and MK2–/– mice to assess the role of MK2 in postmenopausal bone loss. Osteoclastogenesis, bone resorption, and osteoclast gene expression were significantly impaired in monocytes from MK2–/– compared to MK2+/+ mice. Mechanistically, loss of MK2 causes impaired DNA binding of c-fos and nuclear factor of activated T cells cytoplasmic 1 (NFATc1) to tartrate-resistant acid phosphatase (TRAP) and the calcitonin receptor gene promoter. In addition, MK2–/– mice showed an age-dependent increase in trabecular bone mass and cortical thickness, fewer osteoclasts, and lower markers of bone resorption than MK2+/+ mice. Furthermore, MK2–/– mice were protected from ovariectomy-induced bone loss. Osteoblastogenesis and bone formation were unchanged in MK2–/– mice, whereas osteoblast expression of osteoprotegerin (OPG) and serum levels of OPG were higher in MK2–/– than in MK2+/+ mice. Loss of MK2 effectively blocks bone resorption and prevents the development of postmenopausal bone loss. Small-molecule inhibitors of MK2 could thus emerge as highly effective tools to block bone resorption and to treat postmenopausal bone loss. © 2013 American Society for Bone and Mineral Research.
Amyloid toxicity and platelet‐activating factor signaling
Authors: Sirangelo Ivana , Irace Gaetano , Balestrieri Maria Luisa 
Published: November 2012

AbstractAmyloidosis is the accumulation of insoluble proteinaceous aggregates in vivo and is implicated in many neurodegenerative diseases, including Alzheimer's, Huntington's, and Parkinson's diseases. This article briefly reviews the current knowledge of amyloid aggregate toxicity and inflammatory signaling in the nervous system. In particular, we focus our attention on the role of platelet‐activating factor (PAF) as mediator of amyloid cytotoxicity. J. Cell. Physiol. 228: 1143–1148, 2013. © 2012 Wiley Periodicals, Inc.
Effects of low concentrations of Regorafenib and Sorafenib on human HCC cell AFP, migration, invasion, and growth in vitro
Authors: Carr Brian I. , D'Alessandro Rosalba , Refolo Maria G. , Iacovazzi Palma A. , Lippolis Catia , Messa Caterina , Cavallini Aldo , Correale Mario , Di Carlo Antonio 
Published: November 2012

AbstractSorafenib was shown in clinical trial to enhance survival in hepatocellular carcinoma (HCC) patients, but with minimal tumor shrinkage. To correlate several indices of HCC growth at various drug concentrations, HCC cells were grown in various low concentrations of two multikinase inhibitors, Regorafenib (Stivarga) and Sorafenib (Nexavar) and their effects were examined on alpha‐fetoprotein (AFP), cell growth, migration, and invasion. In two AFP positive human HCC cell lines, AFP was inhibited at 0.1–1 µM drug concentrations. Cell migration and invasion were also inhibited at similar low drug concentrations. However, 10‐fold higher drug concentrations were required to inhibit cell growth in both AFP positive and negative cells. To investigate this concentration discrepancy of effects, cells were then grown for prolonged times and sub‐cultured in low drug concentrations and then their growth was re‐tested. The growth in these drug‐exposed cells was found to be slower than cells without prior drug exposure and they were also more sensitive to subsequent drug challenge. Evidence was also found for changes in cell signaling pathways in these slow‐growth cells. Low multikinase inhibitor concentrations thus modulate several aspects of HCC cell biology. J. Cell. Physiol. 228: 1344–1350, 2013. © 2012 Wiley Periodicals, Inc.
Kinetics of hydrolysis of procaine in aqueous and micellar media
Authors: Al‐Blewi Fawzia Faleh , Al‐Lohedan Hamad A. , Rafiquee M. Z. A. , Issa Zuheir A. 
Published: November 2012

AbstractThe kinetics of alkaline hydrolysis of procaine under the pseudo–first‐order condition ([OH−] ≫ [procaine]) has been carried out. N,N‐Diethylaminoethanol and p‐aminobenzoate anion were obtained as the hydrolysis product. The rate of hydrolysis was found to be linearly dependent upon [NaOH]. The addition of cationic cetyltrimethylammonium bromide (CTAB), dodecyltrimethylammonium bromide (DDTAB) and tetradecyltrimethylammonium bromide, and anionic sodium dodecyl sulfate (SDS) micelles inhibited the rate of hydrolysis. The maximum inhibitive effect on the reaction rate was observed for SDS micelles, whereas among the cationic surfactants, CTAB inhibited most. The variation in the rate of hydrolysis of procaine in the micellar media is attributed to the orientation of a reactive molecule to the surfactant and the binding constant of procaine with micelles. The rate of hydrolysis of procaine is negligible in DDTAB micelles. The observed results in the presence of cationic micelles were treated on the basis of the pseudophase ion exchange model. The results obtained in the presence of anionic micelles were treated by the pseudophase model, and the various kinetic parameters were determined. © 2012 Wiley Periodicals, Inc. Int J Chem Kinet 45: 1–9, 2013
A New Class of Ultra‐Efficient Supramolecular Nucleating Agents for Isotactic Polypropylene
Authors: Abraham Frank , Kress Roman , Smith Paul , Schmidt Hans‐Werner 
Published: November 2012

AbstractWe present a family of 2,4,6‐trimethyl‐1,3,5‐benzenetrisamides for ultra‐efficient nucleation of isotactic polypropylene (i‐PP). On the basis of a new symmetrically substituted core, in a series of compounds, the chemical structure of peripheral substituents is systematically varied, introducing branched aliphatic, aromatic, and cycloaliphatic moieties. Some of these compounds are found to promote nucleation of the α‐phase in i‐PP at concentrations as low as 0.00003 wt% only, while concomitantly featuring outstanding thermal properties.
Stability analysis in a soliton fiber ring laser with a hybrid saturable absorber
Authors: Moghaddam M. R. A. , Harun S. W. , Lim K. S. , Ahmad H. 
Published: November 2012

AbstractA stable mode‐locked fiber laser having two rejection ports employing a 4 m long erbium doped fiber is demonstrated. Near transform limited short pulses with a repetition rate of 8.27 MHz are obtained at a wavelength of 1565 nm by using a slow saturable absorber. The pulse width can continuously vary from 1.2 ps to less than 130 fs with a maximum spectral width of 20 nm. Although the changes of the pulse duration over one round‐trip in the resonator is small. However, a comparison of the energy fluctuations from coupler port toward polarizing beam splitter (PBS) port reveals that energy fluctuation is varied from 4.1% to 7.8% and stronger for PBS port. We also find that the low frequency timing jitter for a fixed pump power is stronger for PBS port and the high frequency timing jitter at PBS port is more than twice larger than that of the timing jitter at coupler port. By removing fiber adapters and controlling the environmental airflow in the setup, timing jitter was reduced by an order of magnitude. © 2012 Wiley Periodicals, Inc. Microwave Opt Technol Lett 55:164–170, 2013 2013; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.27220
Design of optical engine for LCOS laser display with rotated diffuser plate
Authors: Li Jia 
Published: November 2012

AbstractBased on the theoretical analysis of the generation of laser speckles, a specific scheme is proposed to reduce composite speckles in the tricolor liquid‐crystal‐on‐silicon laser projector.The rotated diffuser is relatively simple in its optical structure which can be easily implemented. Furthermore, the experiment with regard to the detected images at the receiver is also performed to verify the feasibility of our method. It is shown by simulated results that the rotated diffuser plate can effectively suppress the contrast ratio of laser speckles. © 2012 Wiley Periodicals, Inc. Microwave Opt Technol Lett 55:138–141, 2013; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.27221
Dual band‐notch slot antenna by using a pair of Γ‐shaped slits and Ω–shaped parasitic structure for UWB applications
Authors: Ojaroudi Nasser , Ojaroudi Mohammad 
Published: November 2012

AbstractIn this article, we present a novel design of dual band‐notch printed slot antenna for ultrawideband (UWB) applications. The antenna consists of a square radiating stub and a ground plane structure with two Γ‐shaped slits and Ω‐shaped parasitic structure, which provides a wide usable fractional bandwidth of more than 145% (3.04–17.13 GHz). To increase the impedance bandwidth of the ordinary slot antenna, we use two L‐shaped parasitic structure in the ground plane that with this structure UWB frequency range can be achieved. Additionally, using two Γ‐shaped slits, a single frequency band‐stop performance can be achieved, also to create the second notch frequency, we combine an inverted U‐shaped strip with two L‐shaped parasitic structure, that using this additional inverted U‐shaped strip, Ω‐shaped parasitic structure can be created. Simulated and measured results obtained for this antenna show that the proposed slot antenna offers two notched bands, around 3.67–4.13 GHz and 5.09–5.97 GHz, covering all the 5.2/5.8 GHz WLAN, 3.5/5.5 GHz WiMAX and 4‐GHz C‐band range. The antenna has a small dimension of 20 × 20 mm2. © 2012 Wiley Periodicals, Inc. Microwave Opt Technol Lett 55:102–105, 2013; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.27223
0.18‐μm CMOS wideband passive mixer
Authors: Song Chenyan , Boric‐Lubecke Olga , Lo Ivy 
Published: November 2012

AbstractA 0.18‐μm CMOS wideband passive mixer fully integrated with baluns in IBM7HP process is reported. The mixer exhibits wideband operation, despite the intrinsic narrow‐band magnitude balance of passive baluns. Very low DC offset, of less than 3 mV, is achieved without any DC cancellation circuits, due to high LO–RF isolation. At the RF frequency of 2.4 GHz, the combined IF differential outputs provide conversion loss (CL) of 7.5 dB, input 1 dB compression point (IP1dB) of 6.2 dBm, and input third‐order intercept point (IIP3) of 15.5 dBm. This mixer exhibits broad‐band RF impedance matching with reflection coefficient magnitude better than −9.6 dB through the RF frequency range from 1 to 12 GHz. The CL of 10.1–12.9 dB, IP1dB of 8.6–14.4 dBm, and IIP3 of 16–22.2 dBm are achieved at this frequency range for broad‐band applications. © 2012 Wiley Periodicals, Inc. Microwave Opt Technol Lett 55:23–27, 2013; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.27226
Isolating the singular term of the green's function in the vicinity of the corner formulated by two intersecting waveguides
Authors: Valagiannopoulos Constantinos A. 
Published: November 2012

AbstractA bent waveguide comprised of two vertically intersected unequal parallel‐plate structures is excited by an elementary singular source located into the corner cavity.The electric field, equaling the Green's function, is computed in each region by considering a common singular quantity, the necessary image terms corresponding to infinite planes and a sum describing the mode matching procedure along the separating boundaries. The final form could be used effectively in implementing the scattering integral equations, due to the isolation of the irregular term that can be handled properly. Several graphs representing the variations of the Green's functions and the propagating powers with respect to the oscillating frequency are shown and discussed. © 2012 Wiley Periodicals, Inc. Microwave Opt Technol Lett 55:16–23, 2013;X View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.27227
High‐frequency low‐power fractional frequency multiplier
Authors: Miao Yannan N. , Boon Chirn Chye , Do Manh Anh , Yeo Kiat Seng , Lim Wei Meng 
Published: November 2012

AbstractThe topology of fractional frequency multiplier (FFM) is proposed for high‐frequency and low‐power application. Based on the topology, a × (3/2) FFM is designed and fabricated in a 0.18 μm CMOS technology. The FFM's output power is larger than 0 dBm in its operation range from 15.3 to 18.45 GHz. © 2012 Wiley Periodicals, Inc. Microwave Opt Technol Lett 55:146–149, 2013; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.27236
An etched optical fiber as a vibration sensor
Authors: Kishore Putha , Dinakar Dantala , Vengal Rao P. , Srimannarayana K. 
Published: November 2012

AbstractA center‐etched single‐mode fiber is designed as a vibration senor to monitor the vibrations of a simply supported beam.The sensor works on transmission power loss due to the mode volume mismatch and flexural strain of the fiber due to the bending in the fiber with respect to the bending of the beam. The sensor has high linear response to axial displacement of about 0.8 mm with sensitivity of 32 mV/10 μm strain. The simple design, small size, immune to electromagnetic interference (EMI), and flexible length are all added advantages that may find a place in industry to monitor the vibrations of the beam structures and bridges. © 2012 Wiley Periodicals, Inc. Microwave Opt Technol Lett 55:75–79, 2013; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.27240