bluuebunny/crossref_metadata_2025_split huggingface dataset:
Contributions of maternal emotional functioning to socialization of coping
Authors: Monti Jennifer D. , Rudolph Karen D. , Abaied Jamie L. 
Published: June 2013

This study examined whether maternal emotional functioning—emotional awareness and depression—guides the coping suggestions mothers make to their children in the context of a common childhood stressor (peer victimization). Across two waves of a longitudinal study, 330 mothers and their second graders (mean age ( M) = 7.95 years, SD = .33; 158 boys and 172 girls) completed questionnaires. Emotional awareness predicted more primary control engagement suggestions (directly addressing stress or emotions). Depression predicted fewer cognitive restructuring suggestions (thinking positively) and more cognitive avoidance suggestions (orienting thoughts away from stress). Interactive effects between maternal emotional functioning and child sex also emerged. This study elucidates the impact of mothers’ emotional functioning on how they teach their children to cope with stress.
Inhibitory effect of geraniol in combination with gemcitabine on proliferation of BXPC-3 human pancreatic cancer cells
Authors: Jin Xiaoxin , Sun Jichun , Miao Xiongyong , Liu Guoli , Zhong Dewu 
Published: June 2013

Objective To investigate the inhibitory effect of geraniol alone, or in combination with gemcitabine, on the proliferation of BXPC-3 pancreatic cancer cells. Methods BXPC-3 cells were treated under different conditions: with geraniol at 10, 20, 40, 80 and 160 µmol/l each for 24 h, 48 h or 72 h; with 20 µmol/l geraniol for 24 h or 0 h before 20 µmol/l gemcitabine for 24 h; with 20 µmol/l geraniol for 24 h, 48 h and 72 h following 20 µmol/l gemcitabine for 24 h; or with 20 µmol/l gemcitabine alone as a control. Cell proliferation was assessed and changes in cell morphology were assessed by light and fluorescence microscopy. Apoptosis was detected using flow cytometry. Results Geraniol inhibited BXPC-3 cell proliferation in a time- and dosa-dependent manner. Geraniol alone or combined with gemcitabine induced BXPC-3 cell apoptosis. BXPC-3 inhibition rates with combined treatment were 55.24%, 50.69%, 49.83%, 41.85% and 45.27% following treatment with 20 µmol/l geraniol for 24 h or 0 h before 20 µmol/l gemcitabine for 24 h, or 20 µmol/l geraniol for 24 h, 48 h and 72 h, following 20 µmol/l gemcitabine for 24 h, respectively. Conclusion Geraniol inhibited the proliferation of BXPC-3 cells. Geraniol significantly increased the antiproliferative and apoptosis-inducing effects of gemcitabine on BXPC-3 cells. Maximum inhibition of BXPC-3 cells was achieved with geraniol treatment for 24 h before gemcitabine treatment.
The role of insulin-like growth factor 1 and its receptor in the formation and development of colorectal carcinoma
Authors: Zhang Rong , Xu Guo-Liang , Li Yin , He Long-Jun , Chen Li-Ming , Wang Guo-Bao , Lin Shi-Yong , Luo Guang-Yu , Gao Xiao-Yan , Shan Hong-Bo 
Published: June 2013

Objective To investigate the role of insulin-like growth factor (IGF)-1 and its receptor (IGF1R) in the formation and development of colorectal carcinoma. Methods Colorectal tissue and matching serum samples were collected from patients with adenomatous polyps or carcinoma and healthy control subjects. IGF1R mRNA levels were determined via quantitative real-time reverse transcription–polymerase chain reaction. Serum IGF1 was quantified using enzyme-linked immunosorbent assay. Results Serum IGF1 concentrations and mucosal IGF1R mRNA levels were significantly higher in patients with adenomatous polyps ( n = 24) or carcinoma ( n = 13) compared with healthy control subjects ( n = 13). There was a significant positive correlation between serum IGF1 and mucosal IGF1R mRNA in patients with adenomatous polyps. Conclusions High circulating IGF1 concentrations and mucosal IGF1R expression may play important roles in both the formation and development of colorectal carcinoma. IGF1 and its receptor may be activated before carcinogenesis, and may promote the growth and malignant transformation of adenomatous polyps. IGF1 and IGF1R may be useful biomarkers for evaluating the stage and risk of carcinogenesis.
Reported changes in sexual behaviour and human papillomavirus knowledge in Peruvian female sex workers following participation in a human papillomavirus vaccine trial
Authors: Brown B , Blas M M , Heidari O , Carcamo C , Halsey N A 
Published: June 2013

Summary Limited data exist on the effect of clinical trial participation on sexual behavioural change. Two hundred female sex workers working in Lima, Peru received human papillomavirus (HPV) vaccine in either the standard (0, 2, 6 months) or modified (0, 3, 6 months) schedule. Participants received comprehensive screening and treatment for sexually transmitted infections (STIs), counselling on safe sex practices, education about HPV and the HPV vaccine, contraceptives (oral and condoms) and family planning at each visit. We assessed vaccine completion rates, change in sexual practices, and changes in HPV knowledge before and after participation in the vaccine trial. There were high rates of vaccine completion, 91% overall. The estimated number of reported new and total clients over a 30-day period decreased significantly ( P < 0.001). Knowledge about HPV and HPV-related disease increased among all participants. In addition, all participants listed at least one preventive strategy during the month 7 follow-up survey.
Forecasting Bed Requirement Using Hospital Records
Authors: Dias-Amborcar Yuri , Parulekar Ajit 
Published: June 2013

Purpose: To forecast the bed requirements for a Burns Ward. Methodology: The existing database of hospital admissions and in-patients was analyzed to plan the bed strength for the Burns Ward ICU and Step-down area. We calculated the mean, the median and the mode and studied the pattern of bed occupancy. Utilizing this data, the bed requirement with the gender mix and adult-paediatric patient complement was derived. Findings: The average admission rate for Burns was 15.33 patients per month. In the ICU, the daily mean and the median/mode of in-patients was 2.3 and two, while for Step-down in-patients the mean and median/mode was 7.34 and seven. However, a total of 10–12 beds were occupied in the Burns treatment area for 57–30 days of the study period. Conclusion: Historical data of admissions and bed occupancy enable a realistic prediction of bed requirements for the day to day working of a Burns practice.
Study of Knowledge, Awareness and Practices of Infection Control among ICU Staff of a Multispecialty Tertiary Level Teaching Institute of North India
Authors: Sharma Raman , Jagota Ruchika , Koushal Vipin 
Published: June 2013

Hospital infections are one of the important factors that adversely affect the image and economy of hospitals and ICU is a hotspot of infections. A descriptive and observational study was conducted in ICUs of a Multispecialty Hospital to analyze the knowledge, awareness and practices among staff about infection control.The study was based on checklist based on Ventilator Bundles and Central Line Bundles (IHI) and WHO. Whole staff of ICU was taken as sample size. A significant gap was noticed between actual practices followed and staff know-how. More than 80 per cent of staff was aware of hand hygiene moments and hand washing steps, but less than 25 per cent actually practised it. While 86 per cent of the staff claimed to wear fresh gloves, 57 per cent (239/418 observations) wore in practice. While 68 per cent claimed to follow oral care protocol, only 44 per cent actually did it. Contrary to 67 per cent who responded that they elevate the head of a patient who requires it, 49 per cent did it. And, 57 per cent of the staff followed catheter care practices as per protocol. Lack of accountability, discipline and focus on curative aspects accounts for poor performance towards infection control practices. So, through open communication, regular trainings and self-accountability, infection control standards and patient safety can be achieved.
The Need for Effective Management in African Health Systems
Authors: Adindu Anthonia 
Published: June 2013

Effective health management is critical at every level of African health systems in order to improve services and in turn the current poor health situation in many countries. Specialized professional training equips health-care workers for clinical services, but is limited in preparing them for the management of complex health care systems and organizations. Health management involves technical and social processes for achieving health objectives through effective and efficient use of health resources in view of social, economic, political and cultural realities. Basic functions expected of African health managers include health policy analysis and formulation, health planning, organizing, implementing, leading, coordinating, controlling, monitoring and evaluating services. Health managers at primary, secondary and tertiary levels require additional specialist training in health management to acquire knowledge and skills needed for effective and efficient management of complex health-care organizations. This, in turn, facilitates application of tested theories, systematic approaches and best practices in addressing the health needs of the people. Objective This article advocates effective health-care management in order to achieve the Millennium Development Goals, health goals of the New Partnership for Africa’s Development, national health goals and to promote quality in health care, equity and justice. These culminate in improving health of the people and changing the poor health indices. It also outlines, in brief, the basic functions expected of African health managers and concludes by advocating health-management training for strategic, departmental and operational managers at different levels in the health system. Method I wrote this article based on literature review, experience working with federal and state ministries of health in Nigeria and anecdotal reports from senior health officials and public health students.
Citizens’ Participation in Urban Governance: Quest for Transparency and Accountability
Authors: Singh Shyam 
Published: June 2013

Growing urbanization in India has not only boosted the country’s economy but also presented complex governance challenges that need to be resolved to harness economic opportunities associated with urbanization. One of such challenges is decentralized urban governance where citizens need to have a stake in deciding on how cities should be managed. Experiences implicate that in the view of growing urbanization in the country, the structures of citizen participation provided under the 74th Constitutional Amendment Act are failing in insuring effective citizen participation. The paper, therefore calls for a rethinking in this regard, and discusses experiences of successful citizen participation in urban governance and learning of such experiences. [Formula: see text]
Industries’ Location as Jeopardy for Sustainable Urban Development in Asia: A Review of the Bangladesh Leather Processing Industry Relocation Plan
Authors: Bhowmik Avit Kumar 
Published: June 2013

The article reviews the Bangladesh leather processing industries’ relocation plan by applying the Social Theories of the City and the three environmental economics theories—Willingness to Pay, Pigovian Tax and Hedonic Pricing Method on the data collected by a questionnaire survey among the industries’ owners and from the original project documents. Results prove the strong unwillingness of leather industries’ owners to relocate and pay for relocation, failure at imposing Pigovian tax and the high hedonic prices of the houses including threats to inhabitants’ health in the redeveloped residential area. In addition to high subsidy and compensation, historic growth trends and potential risks of flood and surface water resource pollution of Dhaka defy sustainability issues. Considering three consecutive failures to meet the relocation deadlines, these results claim that redeveloping an environment friendly leather processing zone at the present location will ensure sustainable urban development. [Formula: see text]
Household Quality of Living in Indian States: Analysis of 2011 Census
Authors: Das Bhaswati , Mistri Avijit 
Published: June 2013

Household quality of living (HQL) refers to three broad aspects including housing condition, amenities and assets. The study is an attempt to investigate regional variation of Indian States in terms of HQL based on recently published 2011 Census data. It also investigates the changes of these aspects between two census periods at the national level. The policies launched so far to meet the minimum basic needs and the extent of achievement is also brought in the ambit of discussion. The study reveals that four Southern States namely, Goa, Kerala, Tamil Nadu and Maharashtra; one Western State named Gujarat and four Northern States named Punjab, Himachal Pradesh, Haryana and Uttarakhand demonstrate positive HQL in 2011. Rajasthan, Uttar Pradesh, Madhya Pradesh and whole Eastern and North-Eastern States demonstrate low HQL wherein eastern India demonstrates very poor HQL. Composite index is constructed with the help of PCA (Principal Component Analysis) based on twenty selective variables categorized under three distinctive indices to calculate HQL. [Formula: see text]
Pricing Urban Water Supply
Authors: Aggarwal Veena , Maurya Nidhi , Jain Garima 
Published: June 2013

Right pricing is a key to water sector reforms as it would send correct signals for its use. However, water is generally viewed as a ‘social good’ rather than an ‘economic good’, and hence pricing of water is also done accordingly. This has led to over-exploitation of water resources which has a negative bearing for sustainability. Already many states are water stressed and a large section of the population does not have access to drinking water. State and city level agencies are severely resource constrained and are providing water service to consumers at prices below cost, further aggravating their financial position. Ultimately this results in lower quality of water supply, insufficient network expansion and lesser emphasis development of water projects. This article attempts to understand the existing methodology (rationale) for pricing of urban water supply in different cities in India. It examines tariff setting practices in water sector in countries which at one time faced similar challenges but which were able to successfully reform their sectors. The paper, then examines regulatory and pricing reforms in the electricity sector in India. This is pertinent as electricity is also an essential service, pricing has been for long a political/populist decision, and inefficiencies have affected quality and availability of electricity to end consumers. Regulatory reforms in the distribution segment in the electricity sector were introduced in the late 1990s and early 2000’s and therefore sufficient time has passed to understand the impact of reforms. Based on the learning from the electricity sector and based on international experience, the article recommends principles of pricing of urban retail water supply in India, including suggesting an appropriate tariff structure. It also makes recommendations on issues such as subsides, unaccounted for water and metering. [Formula: see text]
Overview of radionuclide migration experiments in the HADES Underground Research Facility at Mol (Belgium)
Authors: Aertsens M. , Maes N. , Van Ravestyn L. , Brassinnes S. 
Published: June 2013

AbstractIn situmigration experiments using different radiotracers have been performed in the HADES Underground Research Facility (URF), built at a depth of 225 m in the Boom Clay formation below the SCK–CEN nuclear site at Mol (Belgium). Small-scale experiments, mimicking laboratory experiments, were carried out with strongly retarded tracers (strontium, caesium, europium, americium and technetium). Contrary to europium, americium and technetium which are subjected to colloid mediated transport, the transport of strontium and caesium can be described by the classic diffusion retardation formalism. For these last two tracers, the transport parameters derived from thein situexperiments can be compared with the laboratory-derived values. For both tracers, the apparent diffusion coefficients measured in thein situexperiments agree well with the laboratory-derived values.In the large-scale experiments (of the order of metres) performed in the URF, non-retarded or slightly retarded tracers (HTO, iodide and H14CO3–) were used. The migration behaviour of these tracers was predicted based on models applied in performance assessment calculations (classic diffusion retardation) using migration parameter values measured in laboratory experiments. These blind predictions of large-scale experiments agree well in general with the experimental measurements. Fitting the experimentalin situdata leads to apparent diffusion coefficients close to those determined by the laboratory experiments. The iodide and H14CO3–data were fitted with a simple analytical expression, and the HTO data were additionally fitted numerically with COMSOL multiphysics, leading to about the same optimal values.
Development of a reactive transport code MC-CEMENT ver. 2 and its verification using 15-year in situ concrete/clay interactions at the Tournemire URL
Authors: Yamaguchi T. , Kataoka M. , Sawaguchi T. , Mukai M. , Hoshino S. , Tanaka T. , Marsal F. , Pellegrini D. 
Published: June 2013

AbstractHighly alkaline environments induced by cement-based materials are likely to cause the physical and/or chemical properties of the bentonite buffer materials in radioactive waste repositories to deteriorate. Assessing long-term alteration of concrete/clay systems requires physicochemical models and a number of input parameters. In order to provide reliability in the assessment of the long-term performance of bentonite buffers under disposal conditions, it is necessary to develop and verify reactive transport codes for concrete/clay systems. In this study, a PHREEQC-based, reactive transport analysis code (MC-CEMENT ver. 2) was developed and was verified by comparing results of the calculations with in situ observations of the mineralogical evolution at the concrete/argillite interface. The calculation reproduced the observations such as the mineralogical changes in the argillite limited to within 1 cm in thickness from the interface, formation of CaCO3 and CSH, dissolution of quartz, decrease of porosity in the argillite and an increase in the concrete. These agreements indicate a possibility that models based on lab-scale (∼1 year) experiments can be applied to longer time scales although confidence in the models is necessary for much longer timescales. The fact that the calculations did not reproduce the dissolution of clays and the formation of gypsum indicates that there is still room for improvement in our model.
Dissolution experiments of Na- and Ca-montmorillonite in groundwater simulants under anaerobic conditions
Authors: Myllykylä E. , Tanhua-Tyrkkö M. , Bouchet A. , Tiljander M. 
Published: June 2013

AbstractThe effects of simulant groundwater composition, pH and temperature on the dissolution and alteration of Na- and Ca-montmorillonite have been studied. Prior to the experiments, Wyoming type Na-montmorillonite, Swy-2, was purified to decrease the amount of accessory minerals. For Ca-montmorillonite experiments, the interlayer cation Na+ of purified Swy-2 was exchanged with Ca2+. The batch experiments were conducted with the purified montmorillonites in simulated fresh and saline waters at 25°C and 60°C under anaerobic conditions in an Ar atmosphere. The concentrations of Si, Al, Fe and Mg were analysed from ultra-filtered solution samples with High Resolution Inductively Coupled Plasma Mass Spectrometry (HR-ICP-MS) as a function of dissolution time. The pH evolution was also measured. The solid smectite phases were analysed with X-ray Diffraction (XRD) and Scanning Electron Microscopy (SEM). XRD analyses indicated that the nature of the smectite mineral did not change over 140 days. However, the experimental conditions, more or less, modified the structure (e.g. the layer stacking of montmorilllonite; the partial dissolution of the smectite), which cannot be detected by XRD but was evidenced by chemical data, and can be considered as a possible contributor to the stacking faults of the montmorillonite. The log rates (mol g–1 s–1), based on the dissolved amount of Si, varied between –10.64 and –12.13 depending on the experimental conditions.
Experimental investigations of piping phenomena in bentonite-based buffer materials for an HLW repository
Authors: Suzuki K. , Asano H. , Yahagi R. , Kobayashi I. , Sellin P. , Svemar C. , Holmqvist M. 
Published: June 2013

AbstractDuring the installation of the buffer in a deposition hole of an HLW repository, it is necessary to control water flow from the fractured rock into the deposition hole. Water flow with inflow rate greater than 0.001 l/min may cause piping and erosion of the buffer, and may trigger mass redistribution of the buffer, sedimentation and material separation of bentonite materials. This paper describes the condition of parameters which cause piping and erosion; revised conditions which keep advection, inflow rate, buffer component, gap between buffer materials, gap between outside wall and buffer block, and type of water. The results from the experiment show the condition of the self-sealing function of bentonite materials, formation of piping, allowable limit of inflow rate in the case of an Na type bentonite block of 70 wt.% Kunigel V1 and 30 wt.% silica sand, or a pellet of 100 wt.% Kunigel V1. Piping and erosion continue until the engineered barrier (EB) is filled with water, and then the hydraulic gradient becomes small. Piping may lead to erosion and redistribution of material which needs to be taken into account in the long-term performance assessment.
Diffusion of Cs, Np, Am and Co in compacted sand-bentonite mixtures: evidence for surface diffusion of Cs cations
Authors: Sawaguchi T. , Yamaguchi T. , Iida Y. , Tanaka T. , Kitagawa I. 
Published: June 2013

AbstractWe studied the diffusive transport of Cs, Np, Am and Co in compacted sandbentonite mixtures by using the through-diffusion method. The experiments for Cs were performed under various aqueous compositions. Effective diffusivity (De) values of 4.7×10–10 to 5.9×10–9 m2 s–1 were obtained with a somewhat large variation. Apparent diffusivity (Da) values, on the other hand, showed less variation, ranging from 2.0×10–12 to 6.2×10–12 m2 s–1. The results indicated that diffusive flux was proportional to the concentration gradient on the basis of the amount of Cs in the unit volume of the compacted sand-bentonite mixtures rather than the Cs concentration gradient in pore water. Because the former concentration gradient in the mixtures was nearly equal to that of adsorbed Cs, the diffusion of Cs in the mixtures was probably dominated by the concentration gradient of the Cs adsorbed on the mixtures. In addition, the effective/apparent diffusivity of 237Np(IV) and apparent diffusivity of 241Am(III) and 60Co(II) in the mixtures were determined in 0.3/0.03 mol l–1 (NH4)2CO3/Na2S2O4 solution.
microRNA expression profiling identifies molecular signatures associated with anaplastic large cell lymphoma
Authors: Liu Cuiling , Iqbal Javeed , Teruya-Feldstein Julie , Shen Yulei , Dabrowska Magdalena Julia , Dybkaer Karen , Lim Megan S. , Piva Roberto , Barreca Antonella , Pellegrino Elisa , Spaccarotella Elisa , Lachel Cynthia M. , Kucuk Can , Jiang Chun-Sun , Hu Xiaozhou , Bhagavathi Sharathkumar , Greiner Timothy C. , Weisenburger Dennis D. , Aoun Patricia , Perkins Sherrie L. , McKeithan Timothy W. , Inghirami Giorgio , Chan Wing C. 
Published: June 2013

Key PointsAnaplastic large-cell lymphoma has a unique miRNA signature. The miR-17∼92 is an important downstream effector of ALK oncogenic pathway.