bluuebunny/crossref_metadata_2025_split huggingface dataset:
Der „Öffentlichkeitsauftrag der Kirche“ und die Europäische Integration
Authors: Schnabel Patrick Roger 
Published: May 2014

Zusammenfassung
Auf europäischer Ebene sind die verfassten Kirchen in Deutschland nicht nur Rechtsunterworfene, sondern auch politische Akteure. In Ausübung ihres „Öffentlichkeitsauftrages“ vertreten sie einerseits ihre eigenen Interessen und nehmen andererseits Stellung in verschiedensten politischen Debatten. Der Beitrag stellt die allmähliche Institutionalisierung eines Austauschs zwischen Kirchen und europäischen Bürokratien dar und skizziert exemplarische Themen.
Stability and Convergence of Two Three-Field Finite Element Formulations for Elasticity
Authors: Chama A. , Reddy B. D. 
Published: May 2014

Abstract.
In this work analyses are carried out to verify the well-posedness of two three-field formulations for linear elasticity that have been shown to work well in practice, but for which analyses are absent. Both are formulated in three dimensions on tetrahedral elements. The first has as primary unknowns the displacement, pressure, and dilatation, and the second is a formulation with primary unknowns the displacement, pressure and enhanced strain, with the space of enhanced strains spanned by functions that are bubble functions on a surface of the element. It is shown that the first-mentioned formulation is a special case of a general three-field formulation, for which well-posedness conditions have been established. These conditions are used here to show that the pressure-dilatation-displacement formulation is uniformly convergent in the incompressible limit. The pressure-enhanced strain-displacement formulation is not amenable to such an approach; instead, it is reformulated in the form of a standard discrete saddle point problem, and the uniform convergence of the formulation established directly by verifying the ellipticity and inf-sup conditions.
Recurrent fetal seizures diagnosed in the offspring of consanguineous parents
Authors: Benjamin Tara , Hines Karrie A. , Khozaim Kareem , Schubert Frank P. 
Published: May 2014

Abstract
Fetal seizures are relatively rare and most often associated with anomalies or adverse neonatal outcome. We describe a patient who presented in both her G1 and G2 pregnancies with fetal seizures. The second pregnancy was a twin gestation in which only one twin was affected. The fetal seizures were noted by the patient as “extreme rhythmic movement” and were observed on ultrasound. Both neonates were diagnosed with a seizure disorder within 1 day of life. Currently, the seizures are controlled by medication; however, both children have some developmental delay. Additionally, the patient and her partner are consanguineous, suggesting a likely genetic etiology. In utero diagnosis of fetal seizures warrants a multidisciplinary approach to attempt to further define prognosis and provide appropriate treatment and counseling.
Structural changes in spruce wood during different steps of steam explosion pretreatment
Authors: Muzamal Muhammad , Jedvert Kerstin , Theliander Hans , Rasmuson Anders 
Published: May 2014

Abstract
Steam explosion (SE) is a promising hydrothermal pretreatment technology for future biorefineries. In this study, the three steps of the steam explosion process, (1) the steam treatment (2) the explosion, and (3) the impact step were separately considered and their effects on structural changes of wood were studied. The SE experiments were performed on single wood pieces in different experimental set-ups at 7 and 14 bar pressure with 5 and 10 min treatment times. Mercury porosimetry and environmental scanning electron microscopy analyses were conducted to characterise both internal and external changes in the wood. It was found that the explosion step is not responsible for the disintegration of the wood material into small pieces; instead, the disintegration occurs due to impact of softened wood chips. However, the porosity profiles of the tracheids change during the explosion step. Altogether, all three steps of the SE process contribute in a synergistic way to an increase in pore size and total intrusion volume.
Structural insights into calmodulin/Munc13 interaction
Authors: Herbst Sabine , Lipstein Noa , Jahn Olaf , Sinz Andrea 
Published: May 2014

Abstract
Munc13 proteins are essential presynaptic regulators that mediate synaptic vesicle priming and play a role in the regulation of neuronal short-term synaptic plasticity. All four Munc13 isoforms share a common domain structure, including a calmodulin (CaM) binding site in their otherwise divergent N-termini. Here, we summarize recent results on the investigation of the CaM/Munc13 interaction. By combining chemical cross-linking, photoaffinity labeling, and mass spectrometry, we showed that all neuronal Munc13 isoforms exhibit similar CaM binding modes. Moreover, we demonstrated that the 1-5-8-26 CaM binding motif discovered in Munc13-1 cannot be induced in the classical CaM target skMLCK, indicating unique features of the Munc13 CaM binding motif.
Selective modulation of plasmodial Hsp70s by small molecules with antimalarial activity
Authors: Cockburn Ingrid L. , Boshoff Aileen , Pesce Eva-Rachele , Blatch Gregory L. 
Published: May 2014

Abstract
Plasmodial heat shock protein 70 (Hsp70) chaperones represent a promising new class of antimalarial drug targets because of the important roles they play in the survival and pathogenesis of the malaria parasite Plasmodium falciparum. This study assessed a set of small molecules (lapachol, bromo-β-lapachona and malonganenones A, B and C) as potential modulators of two biologically important plasmodial Hsp70s, the parasite-resident PfHsp70-1 and the exported PfHsp70-x. Compounds of interest were assessed for modulatory effects on the steady-state basal and heat shock protein 40 (Hsp40)-stimulated ATPase activities of PfHsp70-1, PfHsp70-x and human Hsp70, as well as on the protein aggregation suppression activity of PfHsp70-x. The antimalarial marine alkaloid malonganenone A was of particular interest, as it was found to have limited cytotoxicity to mammalian cell lines and exhibited the desired properties of an effective plasmodial Hsp70 modulator. This compound was found to inhibit plasmodial and not human Hsp70 ATPase activity (Hsp40-stimulated), and hindered the aggregation suppression activity of PfHsp70-x. Furthermore, malonganenone A was shown to disrupt the interaction between PfHsp70-x and Hsp40. This is the first report to show that PfHsp70-x has chaperone activity, is stimulated by Hsp40 and can be specifically modulated by small molecule compounds.
Low mRNA expression levels of kallikrein-related peptidase 4 (KLK4) predict short-term relapse in patients with laryngeal squamous cell carcinoma
Authors: Foteinou Emmanouela , Kontos Christos K. , Giotakis Aris I. , Scorilas Andreas 
Published: May 2014

Abstract
Several members of the family of tissue kallikrein and kallikrein-related peptidases have been suggested as promising tumor biomarkers with important prognostic significance. However, only one (KLK11) has already been studied in laryngeal squamous cell carcinoma (LSCC) as a potential biomarker for LSCC diagnosis and/or prognosis. Our study investigated the prognostic value of kallikrein-related peptidase-4 (KLK4) mRNA expression as a molecular tissue biomarker in LSCC. For this purpose, KLK4 mRNA expression analysis was performed in 116 cancerous and 74 paired non-cancerous laryngeal tissue specimens obtained from patients that had undergone surgical treatment for primary LSCC. A remarkable downregulation of KLK4 mRNA expression was discovered in laryngeal tumors, compared to non-cancerous laryngeal tissue specimens. KLK4 mRNA expression was also shown to distinguish LSCC from non-cancerous laryngeal tissues. Furthermore, low KLK4 mRNA expression was shown to predict poor disease-free survival, independently of the histological grade and size of the malignant tumor as well as patient TNM stage. According to Kaplan-Meier survival analysis, low KLK4 mRNA expression predicts short-term relapse even among patients with well-differentiated tumors or those at an early TNM stage. Thus, KLK4 mRNA positivity could be regarded as a novel independent indicator of favorable prognosis for the disease-free survival of LSCC patients.
Accuracy of Strain Solution of a Laminated Composite Plate via Galerkin's Method
Authors: Mecitoğlu Zahit , Kazancı Zafer , Balkan Demet 
Published: May 2014

Abstract
This paper deals with the detailed analysis and discussion of nonlinear static analysis of a laminated composite plate subjected to uniform pressure load. Governing equations of the plate are derived by the use of the virtual work principle. The geometric nonlinearity effects are taken into account with the von Kármán large deflection theory of thin plates. Approximate solutions for a simply supported plate are assumed for the plate domain. The single term approximation functions are selected by considering the nonlinear static deformations of plate. The solution is obtained using the Newmark method in MATLAB software. The plate is also modeled and analyzed using ANSYS software using SHELL91 elements. The variation of membrane, linear and nonlinear bending terms are obtained along a characteristic line on the plate and the numerical and finite element results are compared. The results are discussed in detail considering the nonlinear static behavior of the laminated composite plate and the main reasons of discrepancies are discussed. Dynamic behavior of the plate is explained considering the nonlinear static behavior.
Robert Bellarmine’s Idea of the Child Who Dies Unbaptized in the Commentary on the Summa Theologiae
Authors: Cai Yilun 
Published: May 2014

Abstract
In this article, we have investigated Robert Bellarmine’s view on the affliction endured by children who die without being baptized. According to Catholic doctrine, these children go to limbo because they are contaminated by original sin which can only be taken away in baptism. But there was no unanimity among theologians in the Middle Ages and the early modern era on the question whether these children endure physical sufferings. Our investigation has focused on Bellarmine’s commentary on Summa theologiae and has illustrated how he introduced man’s natural desire to see God into his affirmation of the internal suffering endured by children in limbo.
Der Verlust des Menschen Luther
Authors: Leppin Volker 
Published: May 2014

Abstract
The article deals with the impressive work of Gerhard Ebeling on Luther. Ebeling was successful showing the theological impact of church history in the time of the theology of the Word of God. With this, he dealt with contextual questions of the work of Luther, mainly the Late medieval roots of the reformers theology. Nevertheless, Ebeling did his interpretation in a frame of somehow atemporal thinking, losing in this the concrete biography of Martin Luther. The more he stressed the overwhelming relevance of Luther’s theology for our times, he lost the conditions of the development and articulation of this doctrine.
The Shengjing zhijie: A Chinese Text of Commented Gospel Readings in the Encounter between Europe and China in the Seventeenth Century
Authors: Yanrong Chen 
Published: May 2014

Abstract
In the history of the Catholic mission in China from the arrival of the Jesuits in 1582 until the middle of the twentieth century, there was no Catholic Bible translation available. Nonetheless, the presence of various Chinese translations of biblical passages is significant. Among them is the Shengjing zhijie 聖經直解 (Direct/Literal Explanation of the Holy Scripture; ca. 1636–1642), written by the Portuguese Jesuit Manuel Dias (junior) 陽瑪諾 (1574–1659). It is an early translation of the gospel readings from Mass, accompanied with long commentaries and arranged in the order of the liturgical calendar. So far, this biblical, liturgical, and commentarial text has hardly been studied. This paper aims to contextualize the Shengjing zhijie in the history of both the European biblical tradition and the Chinese classical tradition from a cross-cultural perspective. Focusing on the formal traits, this paper associates the textual features of Shengjing zhijie with multiple European and Chinese sources. The scriptures and commentaries composed in the Shengjing zhijie demonstrate that this text is a creative integration of the European tradition and the Chinese tradition.
The effect of adenotonsilectomy on ghrelin, leptin, IGF-1 levels and growth parameters in children with adenotonsillar hypertrophy
Authors: Salman Nergis , Ozturk Gulfer , Akin Istemihan , Kilicaslan Saffet , Demirel Fatma , Delibas Namik 
Published: May 2014

Abstract

Aim: The purpose of this study was to search for the effects of adenotonsillectomy (A&T) on height, weight, and body mass index (BMI), as well as changes in ghrelin, leptin, and insulin-like growth factor 1 (IGF-1) levels in children with adenotonsillar hypertrophy (ATH)-related sleep-disordered breathing (SDB).

Methods: A study cohort of 39 children clinically diagnosed with ATH-related SDB was included in this study. Twenty-three healthy children were included as controls. Height and weight standard deviation scores (SDS) and ghrelin, leptin, and IGF-1 levels of the controls were determined once; in the study group, they were determined preoperatively and in the third month postoperatively.

Results: Preoperative IGF-1 (ng/mL) and ghrelin (pg/mL) levels were significantly higher in the patients than in the controls (322.51±113.10 vs. 256.96±176.73, p<0.05 and 106.08±9.75 vs. 80.11±28.50, p<0.001, respectively). The preoperative height and weight SDS values of the patients were lower than those of the controls (–0.67±1.36 vs. 0.13±1.13, p<0.05 and –0.38±1.35 vs. –0.20±1.29, respectively). The patients’ postoperative height and weight SDS values were significantly higher than their preoperative values (–0.05±1.08 vs. –0.67±1.36, p<0.0001 and 0.00±1.28 vs. –0.38±1.35, p<0.0001, respectively). The mean postoperative IGF-1 levels also were significantly higher than preoperative levels (386.05±130.06 vs. 322.51±113.10, p<0.05, respectively).

Conclusion: Plasma IGF-1 levels are lower in malnourished children, and plasma ghrelin levels are decreased after acute oral food intake and are increased in cachexia and fasting. Therefore, increased serum IGF-1 levels, height and weight SDS values, and decreased ghrelin levels detected postoperatively are useful parameters that help to monitor the development of children with adequate oral intakes.
Big3. Editorial
Authors: Lehmann Christoph , Séroussi Brigitte , Jaulent Marie-Christine 
Published: May 2014

Summary
Objectives: To provide an editorial introduction into the 2014 IMIA Yearbook of Medical Informatics with an overview of the content, the new publishing scheme, and upcoming 25th anniversary.
Methods: A brief overview of the 2014 special topic, Big Data -Smart Health Strategies, and an outline of the novel publishing model is provided in conjunction with a call for proposals to celebrate the 25th anniversary of the Yearbook.
Results: ‘Big Data’ has become the latest buzzword in informatics and promise new approaches and interventions that can improve health, well-being, and quality of life. This edition of the Yearbook acknowledges the fact that we just started to explore the opportunities that ‘Big Data’ will bring. However, it will become apparent to the reader that its pervasive nature has invaded all aspects of biomedical informatics – some to a higher degree than others. It was our goal to provide a comprehensive view at the state of ‘Big Data’ today, explore its strengths and weaknesses, as well as its risks, discuss emerging trends, tools, and applications, and stimulate the development of the field through the aggregation of excellent survey papers and working group contributions to the topic.
Conclusions: For the first time in history will the IMIA Yearbook be published in an open access online format allowing a broader readership especially in resource poor countries. For the first time, thanks to the online format, will the IMIA Yearbook be published twice in the year, with two different tracks of papers. We anticipate that the important role of the IMIA yearbook will further increase with these changes just in time for its 25th anniversary in 2016.
Phosphorylated AKT preserves stallion sperm viability and motility by inhibiting caspases 3 and 7
Authors: Gallardo Bolaños Juan M , Balao da Silva Carolina M , Martín Muñoz Patricia , Morillo Rodríguez Antolín , Plaza Dávila María , Rodríguez-Martínez Heriberto , Aparicio Inés M , Tapia José A , Ortega Ferrusola Cristina , Peña Fernando J 
Published: May 2014

AKT, also referred to as protein kinase B (PKB or RAC), plays a critical role in controlling cell survival and apoptosis. To gain insights into the mechanisms regulating sperm survival after ejaculation, the role of AKT was investigated in stallion spermatozoa using a specific inhibitor and a phosphoflow approach. Stallion spermatozoa were washed and incubated in Biggers–Whitten–Whittingham medium, supplemented with 1% polyvinyl alcohol (PVA) in the presence of 0 (vehicle), 10, 20 or 30 μM SH5, an AKT inhibitor. SH5 treatment reduced the percentage of sperm displaying AKT phosphorylation, with inhibition reaching a maximum after 1 h of incubation. This decrease in phosphorylation was attributable to either dephosphorylation or suppression of the active phosphorylation pathway. Stallion spermatozoa spontaneously dephosphorylated during in vitro incubation, resulting in a lack of a difference in AKT phosphorylation between the SH5-treated sperm and the control after 4 h of incubation. AKT inhibition decreased the proportion of motile spermatozoa (total and progressive) and the sperm velocity. Similarly, AKT inhibition reduced membrane integrity, leading to increased membrane permeability and reduced the mitochondrial membrane potential concomitantly with activation of caspases 3 and 7. However, the percentage of spermatozoa exhibiting oxidative stress, the production of mitochondrial superoxide radicals, DNA oxidation and DNA fragmentation were not affected by AKT inhibition. It is concluded that AKT maintains the membrane integrity of ejaculated stallion spermatozoa, presumably by inhibiting caspases 3 and 7, which prevents the progression of spermatozoa to an incomplete form of apoptosis.Free Spanish abstractA Spanish translation of this abstract is freely available at http://www.reproduction-online.org/content/148/2/221/suppl/DC1.
Defending the Majesty of Islam: Indonesia's Front Pembela Islam (FPI) 1998-2003
Authors: Jahroni Jajang 
Published: May 2014

Indonesia's reformation in 1998 provided an opportunity for the resurgence of Islamic fundamentalist movements. This can be seen from the proliferation of newly formed organisations which aim at either establishing an Islamic state or applying Islamic law. The emergence of these organisations is closely related to the spirit of reformation, where people seem to be free to express their feelings. Almost every day one can see people gathering at the House of Representatives in Senayan, Jakarta, in order to express their aspirations to the members of parliament.DOI: 10.15408/sdi.v11i2.601
Nahḍat al-‘Ulamā’ bay al-Bātinīyah al-Jāwīyah wa al-Taṣawwuf al-Islāmī: ‘Arḍun wa Munāqashāt
Authors: Nursamad Muhammad 
Published: May 2014

Three kebatinan "holy books", Darmogandul, Gatoloco, and Wirid Hidayat Jati, are the point of focus in the analysis of doctrinal sources. The tendency of these three texts to ridicule santri(students at Islamic boarding schools or pesantren) strengthens the impression that the Dutch colonial government used kebatinan to attack Islam. At the very least, this "cultural war" was closely linked to these texts.DOI: 10.15408/sdi.v11i2.604
Mumārasat al-Sulūk bi Minangkabau: Tarbīq al-Ta’ālim al-Islāmīyah ‘alā al-Thaqāfah al-Maḥallīyah
Authors: Denti Sri 
Published: May 2014

This article presents discussions about "suluk (mystic) rituals" in Minangkabau, which can be seen as a form of expression of Islamic rituals, in this context tariqah (Sufi order) practices, which have been integrated into local rituals and culture. It explains that the suluk tradition in Minangkabau developed in exclusive areas, in this context the hinterland or the area of Minangkabau where matrilineal traditions are still strong, not coastal areas with quite a high level of socialisation, because social interaction is quite significant.DOI: 10.15408/sdi.v11i2.605
Kitāb al-Tuḥfah al-Rāgibīn wa al-Radd ‘alā ‘Aqīdah al-Wujūdīyah bi Fālimbānj fi al-Qarn al-Thāmin ‘Ashar al-Mīlādī
Authors: Kalsum Nyimas Umi 
Published: May 2014

This article tries to discuss one of religion waorks written by al-Palimbani, Tuhfah al-Ragibin, presented the discussion of the author's response towards wujudiyyah, a text that widely spread in Palembang at the time. In line with al-Raniri in Aceh, al-Palimbani divided wujudiyyah's doctrine into two categories: wujudiyyah mulhid and wujudiyyah muwahhid.DOI: 10.15408/sdi.v11i3.597
Al-Ḥarakah al-Fikrīyah wa al-Turāth ‘Inda al-Shaykh Ihsan Jampes Kediri: Mulāḥaẓah Tamhīdīyah
Authors: Barizi Ahmad 
Published: May 2014

This paper tries to present an early discussion on tradition and intellectual movement of Kyai Ihsan Jampes, which has not been intellectually discussed. From various legitimate sources, there are 12 religious work written by Kyai Ihsan Jampes, both in printed forms and manuscript. It worth noted, different from general works of ulama in the Malay-Indonesia world, Kyai Ihsan Jampes had never learned Islam from Middle East ulama. He had only visited Mecca and Medina, which are the center of Islamic knowledge, once. And it was purely for pilgrimage purposes. However, this did not prevent him to be a productive writer.DOI: 10.15408/sdi.v11i3.598
The Mainstreaming of Pesantrens and Madrasahs in Indonesia
Authors: Jamhari Jamhari 
Published: May 2014

The project of this article has focused on six strategic groups in pesantrens and madrasahs. These are: 1)Kyai (male religious leaders) and Nyai (female religious leaders) of pesantren salaf; 2) Kyai and Nyai of pesantren khalaf; 3) key community leaders; 4) principals ofmadrasah aliyahmadrasah aliyah; and 6) student leaders of madrasah aliyah.DOI: 10.15408/sdi.v12i2.593
Al-Tarbīyah al-Muta’addidah al-Thaqāfātīyah: Tanmīyah al-Dimukraṭīyah bi Indūnīsīyā
Authors: Namsa M. Yunus 
Published: May 2014

This article presents a comprehensive study of the conflicts in Indonesia, using the conflict in North Maluku as a case study. As is well-known, the long-drawn-out conflict that began in 1999 resulted in many deaths. The Indonesian Government reported (based on 1999-2000 data) that about 1,842 people had died as a direct result of the conflict. Of that total, the majority (1,797) were civilians, while the policemen (32) and the army soldiers (13) accounted for a small amount of the death toll. Other sources reported that the actual death toll was in fact 2,084 people, with a further 1,003 seriously wounded and 756 with minor injuries. In addition to the loss of human life, and great deal of public and private property was also lost. This included 20,241 homes, 200 schools, and 144 places for worship (both mosques and churches).DOI: 10.15408/sdi.v12i3.584
Taqālid Tuallif Kutub al-Tafsīr al-Malayūwīyah wa al-Jāwīyah wa al-Sundāwīyah: Muḥawalah li Rasm Kharīṭah
Authors: Nurtawab Ervan 
Published: May 2014

This article examines the tradition of translating and interpreting the Qur'an in Javanese, Malay, and Sundanese, with a focus on manuscripts since the beginning of the 20th century. The author of this article has sought to show the dynamics of the translations and interpretations of the Qur'an in these three languages since the 17th century, while further explaining the characteristics of these works in the respective periods.DOI: 10.15408/sdi.v12i3.585