bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prenatal Detection of Fetal Anomalies at the 11- to 13-Week Scan—Part I: Brain, Face and Neck
Authors: Illescas Tamara , Sepulveda Waldo , Adiego Begona , Martinez-Ten Pilar 
Published: October 2013

ABSTRACT
In the last 20 years, the role of first-trimester ultrasound screening has expanded from individual calculation of the risk of aneuploidy through measurement of the nuchal translucency to a powerful technique to evaluate important aspects of the fetal anatomy. Traditionally, the full anatomy scan for detection of structural anomalies has been performed in the second trimester of pregnancy. However, with the implementation of the first-trimester scan at 11 to 13 weeks of gestation many of the structural anomalies traditionally detected in the second trimester can now be identified earlier in pregnancy. In the first part of this review we discuss the main ultrasound findings that may facilitate the prenatal detection of fetal brain, face and neck abnormalities in the first trimester of pregnancy.

How to cite this article
Sepulveda W, Illescas T, Adiego B, Martinez-Ten P. Prenatal Detection of Fetal Anomalies at the 11- to 13-Week Scan—Part I: Brain, Face and Neck. Donald School J Ultrasound Obstet Gynecol 2013;7(4):359-368.
Current Role of 3D/4D Sonography in Obstetrics and Gynecology
Authors: Pashaj Sonila , Merz Eberhard 
Published: October 2013

ABSTRACT
Modern 3D/4D sonography provides a routine method not only for storing single image planes as in 2D ultrasound but also for storing complete sets of volume data in the computer memory. Once acquisition is completed, all volumes can be accessed from the memory and normal and abnormal findings in both obstetrics and gynecology can be demonstrated in different display modes. Furthermore digital storage of volumes permits virtual examinations by reloading of volumes and navigating through them in the absence of the patient.
This review article would like to give an illustration of the latest technologies in 3D/4D ultrasound in obstetrics and gynecology.

How to cite this article
Merz E, Pashaj S. Current Role of 3D/ 4D Sonography in Obstetrics and Gynecology. Donald School J Ultrasound Obstet Gynecol 2013;7(4):400-408.
Improving our Knowledge in Twins: The Role of Ductus Venosus in the First Trimester
Authors: Montenegro Nuno , Matias Alexandra 
Published: October 2013

ABSTRACT
Ductus venosus (DV) is a tiny vessel with a central role in fetal circulation both in singletons and multiples. In the present review we detail the contribution of DV evaluation in twin pregnancies in the first trimeter of pregnancy. The higher prevalence of abnormal A-wave in fetuses with abnormal karyotype and/or cardiac defects made DV evaluation a useful marker for the screening of chromosomal abnormalities and fetal cardiac anomalies. In dichorionic (DC) pregnancies, DV blood flow assessment reproduces the role of NT in the screening for aneuploidies, just as in singleton pregnancies. In monochorionic (MC) twin pregnancies, the Doppler assessment of DV blood flow improves the detection of those at higher risk of developing twin-to-twin transfusion syndrome or growth discrepancy later in pregnancy. As for singletons, DV should be systematically evaluated in all first trimester scans for a more performant screening in multiples.

How to cite this article
Matias A, Montenegro N. Improving our Knowledge in Twins: The Role of Ductus Venosus in the First Trimester. Donald School J Ultrasound Obstet Gynecol 2013;7(4):409-414.
Ultrasound Assessment and Surgical Treatment of Twin-Twin Transfusion Syndrome
Authors: Kontopoulos Eftichia V , Quintero Rubén A 
Published: October 2013

ABSTRACTThe ultrasound diagnosis, management and treatment of twintwin transfusion syndrome (TTTS) have had a remarkable number of positive developments in the last 20 years. Together, they have resulted in TTTS being the most common condition seen and treated in fetal therapy centers today. This chapter discusses the basic ultrasound assessment of TTTS patients in a step-by-step fashion, to provide a structure to the sonographic examination. This includes review of the diagnostic criteria, the sonographic assessment of disease severity and preoperative ultrasound assessment. The chapter also reviews the rationale for, as well as the fundamental laser technique and its variations, including the nonselective technique, selective laser photocoagulation of communicating vessels (SLPCV), sequential selective laser photocoagulation of the communicating vessels (SQLPCV) and the ‘Solomon’ technique, and provides potential explanations for the outcome differences of each technique. Future developments in terms of surgical technique and long-term outcome studies are also discussed.How to cite this articleQuintero RA, Kontopoulos EV. Ultrasound Assessment and Surgical Treatment of Twin-Twin Transfusion Syndrome. Donald School J Ultrasound Obstet Gynecol 2013;7(4):415-425.
Diagnostic Prenatal Invasive Procedures in Obstetrics
Authors: Angelica Zoppi Maria 
Published: October 2013

ABSTRACT
In 1977, we performed in Cagliari the first invasive prenatal diagnosis for beta-thalassemia in Europe, using fetal blood sampling by placentacentesis and chain globins analysis at 20th week of gestation. Since then we have performed more than 8,000 fetal diagnoses for beta-thalassemia using placentacentesis, fetoscopy, cordocentesis, cardiocentesis, amniocentesis, transcervical-chorionic villus sampling (TC-CVS), transabdominal (TA-CVS) and preimplantation genetic diagnosis (PGD) by embryo biopsy.
Since 1986 we have been using for the beta-thalassemia and other single gene diseases only TA-CVS and PGD and DNA polymerase chain reaction (PCR) analysis.
For karyotype we have been using mostly TA-CVS and amniocentesis and traditional cytogenetic analysis, in several cases also fluorescent in situ hybridization (FISH) and comparative genomic hybridization (CGH) array.

How to cite this article
Monni G, Zoppi MA, Iuculano A. Diagnostic Prenatal Invasive Procedures in Obstetrics. Donald School J Ultrasound Obstet Gynecol 2013;7(4):426-428.
Transvaginal Sonography in Infertility
Authors: Bora Rishabh , Malhotra Bora Neharika 
Published: October 2013

ABSTRACT
Transvaginal sonography offers a very accurate, easy and reproducible method to evaluate the female pelvis and the female factors of infertility. The addition of color gives us more information about organ perfusion and addition of 3D has opened a new dimension to diagnosis of pelvic pathologies. Transvaginal sonography has an important role in the management of infertility. Serial pelvic ultrasound examinations are useful in monitoring patients undergoing ovulation induction using ovulation-inducing drugs. In addition, the correct prediction of timing of ovulation is critical for infertility therapies such as intrauterine insemination, artificial or therapeutic insemination using donor sperm and the timing of intercourse during ovulation induction therapies.
More than any other new method, ultrasound has made significant improvements in modern management of infertility.

How to cite this article
Malhotra N, Malhotra J, Bora NM, Bora R, Malhotra K. Transvaginal Sonography in Infertility. Donald School J Ultrasound Obstet Gynecol 2013;7(4):462-474.
Late Onset Brain Anomalies: Tumors, Cysts and Hemorrhages
Authors: Volpe Grazia , D'Addario Vincenzo 
Published: October 2013

ABSTRACT
Most fetal brain anomalies can be diagnosed during the second trimester scan performed to screen for fetal malformations. However; there are some cerebral pathologies which become evident only during the late second and third trimester of pregnancy. Occupying space lesions, such as tumors, cysts, vascular malformations and hemorrhages frequently appear as late onset complications in a fetus diagnosed as normal during the second trimester anomaly scan.
In this review paper the sonographic patterns of these anomalies will be described. Particular attention will be paid to the prognosis, which is extremely variable, ranging from the lethal outcome of huge brain tumors, to severe neurological handicap of severe hemorrhages or leukomalacic cysts, to normal postnatal outcome of some arachnoid cysts.

How to cite this article
D'Addario V, Capuano P, Volpe G. Late Onset Brain Anomalies: Tumors, Cysts and Hemorrhages. Donald School J Ultrasound Obstet Gynecol 2013;7(4):484-491.
KANET Diagnosis of Fetal Akinesia Deformation Sequence at 30 Weeks
Authors: Honemeyer Ulrich , Pour-Mirza Afshin , Kasirsky Jennifer 
Published: October 2013

ABSTRACT
We are reporting the case of a 40 years old 2nd gravida, 1 para. At 26 weeks of the reported pregnancy, fetal movements stopped suddenly and almost completely within 24 hours. At 30w2d she was referred for Doppler scan and fetal biometry. In ultrasonography (US) normal morphology was seen. Biometry corresponded to 28w1d. Outstanding observation was the permanent immobility of the entire fetus in four-dimensional ultrasound (4D-US). We found during two US examinations an abnormal KANET test, the first at 30w2d with a score of 3 points, and the second at 31w4d, with a score of 4 points. Cardiotocography (CTG) demonstrated complete loss of variability and accelerations. The patient developed severe polyhydramnios at 33 weeks. After lower segment cesarean section (LSCS) because of breech position, the newborn required ventilation, and passed away after 5 days.

How to cite this article
Honemeyer U, Kasirsky J, Pour-Mirza A, Kurjak A. KANET Diagnosis of Fetal Akinesia Deformation Sequence at 30 Weeks. Donald School J Ultrasound Obstet Gynecol 2013;7(4):500-505.
Handing Down and Writing Down: Metadiscourses of Tradition among the Bandanese of Eastern Indonesia
Authors: Kaartinen Timo 
Published: October 2013

Abstract
The topic of this article is the reproduction of tradition among the Bandanese, an Eastern Indonesian people. I analyze the style and rhetoric of songs that tell about ancestral sea voyages. The question I address is what happens to the value of the songs as tradition when they turn from oral performances into circulating texts. I explore several contexts of performance and transmission and argue that the songs can be embedded in lived realities in different ways. By writing the songs down, the Bandanese reorganize their tradition into new genres of text and performance. Their metadiscourse of tradition affirms that these genres represent the exemplary, complete language of the ancestors. Although singers and writers affirm the artistic, textual, and cultural completeness of their arts, they are reluctant to pass on their knowledge in an already integrated form.
Fonctions critiques de la tutelle auprès d’élèves en échec scolaire
Authors: Vannier Marie-Paule 
Published: October 2013

Cet article rend compte d’observations réalisées auprès d’adolescents, scolarisés dans des institutions dédiées aux élèves reconnus en échec dans le cursus normal du Collège. L’analyse des pratiques enseignantes met en évidence la difficulté à maintenir les conditions d’un progrès cognitif pour tous. Ce travail aborde la question de la transposition du concept de tutelle (Bruner, 1983) dans un cadre scolaire. Quelle(s) théorie(s) de référence pour décrire et comprendre le travail de l’enseignant et l’appréhender dans ces aspects « critiques » ?
En quête d’une approche culturelle appliquée à l’enseignement du français, langue première, au secondaire
Authors: Côté Héloïse , Simard Denis 
Published: October 2013

Le ministère de l’Éducation du Québec a entrepris de réformer les programmes d’études et il prescrit qu’une approche culturelle préside à l’enseignement de toutes les matières (Gouvernement du Québec, 1997). Toutefois, entre la prescription et l’application de celle-ci réside une multiplicité de significations qui amènent les enseignants de français au secondaire à s’interroger : que pourrait signifier une approche culturelle appliquée à leur discipline ? Grâce à l’analyse de discours tenus sur la langue et la culture en lien avec l’éducation, il est possible de cerner six dimensions constitutives de l’approche culturelle.
La part du lecteur de textes littéraires dans la classe de français
Authors: Mercier Jean-Pierre 
Published: October 2013

Cet article examine la place et le rôle du sujet lecteur de textes littéraires dans la classe de français. Il ne s’agit plus, dans le cadre théorique que nous exposons, de penser exclusivement à former un lecteur qui comprend et interprète les textes littéraires à la faveur d’une pensée abstraite et rationnelle. Les conceptions gravitant autour de la notion de sujet lecteur font voir que la lecture émanant d’un sujet est nourrie de sa culture personnelle, conséquence de son histoire, amalgamée aux dimensions affectives, sociales et cognitives de sa subjectivité. Dans une perspective didactique, nous proposons de retenir deux critères pour l’élaboration des dispositifs de lecture des textes littéraires : le critère du climat et le critère d’autorisation.
Perception de la fréquence d’apparition des comportements perturbateurs par des stagiaires en enseignement de l’éducation physique et à la santé (EPS)
Authors: Desbiens Jean-François , Lanoue Sèverine , Turcotte Sylvain , Tourigny Jean-Sébastien , Spallanzani Carlo 
Published: October 2013

Les enseignants débutants en éducation physique et à la santé (EPS) ont des habiletés insuffisantes pour gérer efficacement la complexité des situations d’apprentissage. Leurs capacités d’observer les éléments pertinents des situations, de les traiter et de les interpréter sont limitées. Cette étude consacrée à des stagiaires finissants avait pour objectifs spécifiques de : 1) comparer la fréquence perçue et effective des comportements perturbateurs (CP) selon leur nature; 2) comparer la fréquence perçue et effective des CP selon leur moment d’apparition. Les résultats montrent que les perceptions des stagiaires finissants sont variables et qu’elles ne correspondent pas fidèlement aux CP effectivement dénombrés selon le degré d’intensité de ces derniers. Cependant, elles reflètent de manière fiable leur moment d’apparition. Le poids des CP dans l’économie de la séance n’est apparemment pas uniquement lié à leur seule fréquence, mais à d’autres facteurs qui restent à approfondir. Les auteurs proposent en conclusion des pistes d’améliorations des dispositifs de formation initiale à l’enseignement afin que les stagiaires deviennent de meilleurs observateurs et interprètes des comportements des élèves.
Injustices perçues en éducation physique et sportive
Authors: Lentillon-Kaestner Vanessa 
Published: October 2013

De nombreux travaux se sont intéressés aux inégalités présentes en éducation physique et sportive (EPS), mais les travaux portant sur les élèves sont plus rares. L’objet de cette étude est de déceler les injustices perçues par les élèves d’établissements du second degré (collèges et lycées) en EPS. Une question ouverte a été posée à 83 élèves lors d’entretiens : Percevez-vous des injustices en EPS ? Si oui, à quel(s) niveau(x) ? Une analyse de contenu de type logicosémantique a été menée : seule la méthode inductive a été utilisée. Les élèves perçoivent prioritairement des injustices au plan de l’évaluation puis des interactions enseignant-élèves. Les injustices perçues varient selon les caractéristiques des élèves et des établissements fréquentés. Elles concernent prioritairement les domaines qui importent à l’élève.
Compagnonnage réflexif et intervention éducative
Authors: Beckers Jacqueline 
Published: October 2013

L’article présente un dispositif d’accompagnement de futurs enseignants en stage qui vise à leur faire prendre conscience de leur modèle opératif et à le réguler pour garantir à leur intervention son caractère éducatif. Ces accompagnements sont gérés par de futurs formateurs, eux aussi stagiaires se préparant au métier de formateurs d’enseignants. Chaque duo (un futur enseignant et un futur formateur) s’engage dans une « démarche régulatrice personnalisée » qui associe étroitement observations des pratiques du futur enseignant en classe par le futur formateur et échanges menés sur la base d’une trace de ces pratiques lors d’entretiens de régulation. Au cours de ceux-ci, sont analysés les liens entre les intentions éducatives du futur enseignant, le déroulement effectif de ses actions professionnelles, la manière dont il leur donne sens et se voit ou non devenir enseignant. La retranscription d’un entretien de régulation illustre à la fois la manière dont le futur enseignant s’approprie les outils de la formation, généralise ses démarches de gestion de la classe et des apprentissages et se construit progressivement comme professionnel enseignant.
Philosophie et littérature de jeunesse : la vérité, la fiction et la vie
Authors: Chirouter Edwige 
Published: October 2013

Prendre en compte les interrogations métaphysiques des enfants est une grande tendance de la littérature de jeunesse contemporaine. L’enfant n’est plus considéré comme un petit être innocent, mais comme un sujet qui se pose des questions fondamentales sur le sens de la vie et du monde. L’enfant fait à chaque instant l’expérience de l’étonnement devant le monde. La question de la Vérité notamment le passionne : Qu’est-ce qui est vrai, qu’est-ce qui est faux ? Quelle est la différence entre une croyance et un savoir, etc. La littérature de jeunesse permet de réfléchir sur ces questions métaphysiques. À l’école élémentaire, les enseignants peuvent ainsi mettre en réseau des ouvrages sur ces questions et engager, à partir des lectures, des discussions philosophiques.
La littérature illustrée comme objet didactique : l’exemple de l’Histoire sous la loupe du LIMIER
Authors: Martel Virginie , Boutin Jean-François 
Published: October 2013

Le présent texte s’articule autour de l’idée maitresse de littérature illustrée, qui devient d’ailleurs le principal objet d’investigation d’un regroupement de chercheurs en didactique et en pédagogie de l’Université du Québec à Rimouski (UQAR). Après avoir brièvement présenté ce groupe appelé LIMIER, en raison des thèmes rassembleurs qui lui ont donné naissance (littérature illustrée, médiathèque, interventions en éducation et recherche), le concept de littérature illustrée est étudié de façon critique. Par la suite, un problème didactique est analysé de façon exhaustive : il s’agit de démontrer la pertinence du recours aux textes littéraires illustrés pour appuyer l’essor des pratiques d’enseignement- apprentissage d’une discipline incontournable en sciences humaines, soit celle de l’Histoire.
Heterogeneity of Treatment Effects in Internet- and Mobile-Based Interventions for Depression
Authors: Terhorst Yannik , Kaiser Tim , Brakemeier Eva-Lotta , Moshe Isaac , Philippi Paula , Cuijpers Pim , Baumeister Harald , Sander Lasse Bosse 
Published: July 2024

ImportanceWhile the effects of internet- and mobile-based interventions (IMIs) for depression have been extensively studied, no systematic evidence is available regarding the heterogeneity of treatment effects (HTEs), indicating to what extent patient-by-treatment interactions exist and personalized treatment models might be necessary.ObjectiveTo investigate the HTEs in IMIs for depression as well as their efficacy and effectiveness.Data SourcesA systematic search in Embase, MEDLINE, Central, and PsycINFO for randomized clinical trials and supplementary reference searches was conducted on October 13, 2019, and updated March 25, 2022. The search string included various terms related to digital psychotherapy, depression, and randomized clinical trials.Study SelectionTitles, abstracts, and full texts were reviewed by 2 independent researchers. Studies of all populations with at least 1 intervention group receiving an IMI for depression and at least 1 control group were eligible, if they assessed depression severity as a primary outcome and followed a randomized clinical trial (RCT) design.Data Extraction and SynthesisThis study followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses reporting guidelines. Risk of bias was evaluated using the Cochrane Risk of Bias Tool. HTE was investigated using logarithmic variance ratios (lnVR) and effect sizes using Hedges g. Three-level bayesian meta-regressions were conducted.Main Outcomes and MeasuresHeterogeneity of treatment effects was the primary outcome of this study; magnitudes of treatment effect sizes were the secondary outcome. Depression severity was measured by different self-report and clinician-rated scales in the included RCTs.ResultsThe systematic review of 102 trials included 19 758 participants (mean [SD] age, 39.9 [10.58] years) with moderate depression severity (mean [SD] in Patient Health Questionnaire–9 score, 12.81 [2.93]). No evidence for HTE in IMIs was found (lnVR = −0.02; 95% credible interval [CrI], −0.07 to 0.03). However, HTE was higher in more severe depression levels (β̂ = 0.04; 95% CrI, 0.01 to 0.07). The effect size of IMI was medium (g = −0.56; 95% CrI, −0.46 to −0.66). An interaction effect between guidance and baseline severity was found (β̂ = −0.24, 95% CrI, −0.03 to −0.46).Conclusions and RelevanceIn this systematic review and meta-analysis of RCTs, no evidence for increased patient-by-treatment interaction in IMIs among patients with subthreshold to mild depression was found. Guidance did not increase effect sizes in this subgroup. However, the association of baseline severity with HTE and its interaction with guidance indicates a more sensitive, guided, digital precision approach would benefit individuals with more severe symptoms. Future research in this population is needed to explore personalization strategies and fully exploit the potential of IMI.
Upconverting Ultra‐Thin Bi2O2CO3 Nanosheets for Synergistic Photodynamic Therapy and Radiotherapy
Authors: Shi Shuzhi , Liao Cheng , Liu Yufu , Liu Jinming , Liu Jinliang , Zhang Yi , Zhang Yong , Mei Qingsong 
Published: July 2024

AbstractSynergistic therapy has become the major therapeutic method for malignant tumors in clinical. Photodynamic therapy (PDT) and radiotherapy (RT) always combine together because of their identical anti‐tumor mechanisms, that is reactive oxygen species are generated by the use of radiosensitizers after irradiation by X‐ray to efficiently kill cancer cells, PDT also follows similar mechanism. Full exposure of energy‐absorbing species in nanomaterials to X‐ray or near‐infrared light irradiation makes the energy interchange between nanomaterials and surrounding H2O or dissolved oxygen easier, however, it remains challenging. Herein, an ultrathin two‐dimensional (2D) nanosheet (NS) is developed, Bi2O2CO3, doped with lanthanide ions to give out upconversion luminescence, where the high Z elements Bi, Yb, and Er promote the radio‐sensitizing effect. To the surprise, lanthanide activator ions gave out completely different luminescence properties compared with traditional upconversion nanoparticles. Less dopant of Er ions in nanosheets lattice resulted in brighter red emission, which provides more efficient PDT. Under RT/PDT combined treatment, NS shows a good tumor growth‐inhibiting effect. In addition, synergistic therapy requires lower radiation dose than conventional radiotherapy and lower light power than single photodynamic therapy, thus greatly reducing radiation damage caused by RT and thermal damage caused by PDT.