bluuebunny/crossref_metadata_2025_split huggingface dataset:
Growth and morphological analysis of segmented AuAg alloy nanowires created by pulsed electrodeposition in ion-track etched membranes
Authors: Schubert Ina , Burr Loic , Trautmann Christina , Toimil-Molares Maria Eugenia 
Published: June 2015

Background: Multicomponent heterostructure nanowires and nanogaps are of great interest for applications in sensorics. Pulsed electrodeposition in ion-track etched polymer templates is a suitable method to synthesise segmented nanowires with segments consisting of two different types of materials. For a well-controlled synthesis process, detailed analysis of the deposition parameters and the size-distribution of the segmented wires is crucial.Results: The fabrication of electrodeposited AuAg alloy nanowires and segmented Au-rich/Ag-rich/Au-rich nanowires with controlled composition and segment length in ion-track etched polymer templates was developed. Detailed analysis by cyclic voltammetry in ion-track membranes, energy-dispersive X-ray spectroscopy and scanning electron microscopy was performed to determine the dependency between the chosen potential and the segment composition. Additionally, we have dissolved the middle Ag-rich segments in order to create small nanogaps with controlled gap sizes. Annealing of the created structures allows us to influence their morphology.Conclusion: AuAg alloy nanowires, segmented wires and nanogaps with controlled composition and size can be synthesised by electrodeposition in membranes, and are ideal model systems for investigation of surface plasmons.
Zionstheologische Konzepte im Sacharjabuch zwischen Abgrenzung und universaler Öffnung anhand von Sach 2
Authors: Mentemeier Christina 
Published: June 2015

Qu’est-ce qui constitue une identité qui, après les expériences de l’exil, est associée à Jérusalem ou bien à Sion ? Zac 2 montre la relation à YHWH comme facteur décisif, fondateur d’identité. YHWH laisse entrevoir qu’il sera de nouveau accessible en son lieu choisi et qu’il participe à l’aménagement de cet espace vital pour son peuple de manière nouvelle et rassurante. Suivant Zac 2,15s, un élargissement et une ouverture de l’entité en principe exclusive du peuple sont possibles sans que cela mette en danger son identité particulière. Des fils multiples s’entremêlent dans les récits des visions et les promesses de salut en Zac 2 et décrivent les rapports respectifs entre YHWH, Jérusalem/Sion et les hommes.
Une philosophie de l’Europe
Authors: Ferry Jean-Marc 
Published: June 2015

L’idée d’Europe est-elle morte ? Une modernité marquée du sceau de la raison instrumentale, du désenchantement du monde, et de l’individualisme possessif en a-t-elle eu raison ? Ce n’est pas l’explication que l’on donne aujourd’hui du « malaise européen », plutôt lié au désenchantement survenu cinquante ans après le lancement d’un projet visant paix, prospérité et justice. Face à l’impression d’une « perte de sens », seule la construction d’une Philosophie de l’Europe peut permettre de dépasser les apories nées des difficultés pratiques liées à la gestion de la réalité actuelle du continent.
Spectral-Domain OCT Analyses of Macular Changes After Ranibizumab Therapy for Type 1 Retinopathy of Prematurity
Authors: Erol Muhammet Kazim , Coban Deniz Turgut , Özdemir Özdemir , Tunay Zuhal Özen , Bilgin Ahmet Burak , Dogan Berna 
Published: June 2015

Purpose:
To investigate the clinical and macular spectral-domain optical coherence tomography (SD-OCT) findings after intravitreal ranibizumab treatment for type 1 retinopathy of prematurity (ROP).

Methods:
Eighteen eyes of 10 premature infants with type 1 ROP were retrospectively studied. All eyes were treated with intravitreal ranibizumab as monotherapy. Macular SD-OCT was performed before and after intravitreal ranibizumab therapy using a portable SD-OCT machine; the follow-up images were taken 1 day, 1 week, 1 month, and 2 months after therapy.

Results:

Among the 10 infants, there were six males and four females. Mean central foveal thickness before and 2 months after intravitreal ranibizumab was 292.5 ± 61.4 and 171.6 ± 21.7 µm, respectively. Differences were statistically significant (
P
= .01). Sixteen eyes of eight patients had macular edema before treatment. Two eyes of two patients developed a crack in the outer hyperreflective line on SD-OCT corresponding with retinal pigment epithelium with serous retinal detachment 1 day after treatment. Macular edema regressed in all patients 2 months after intravitreal ranibizumab therapy. Mean follow-up time was 11.4 ± 1.5 months. No recurrence was seen except in both eyes of one patient treated with intravitreal ranibizumab monotherapy.

Conclusions:
Intravitreal ranibizumab injection is effective for the treatment of type 1 ROP as a monotherapy agent; however, macular changes not seen with indirect ophthalmoscope may develop.

[
J Pediatr Ophthalmol Strabismus.
2015;52(3):152–158.]
Goniotomy for Steroid-Induced Glaucoma: Clinical and Tonographic Evidence to Support Therapeutic Goniotomy
Authors: Choi Eun Young , Walton David S. 
Published: June 2015

Purpose:
To report the surgical results of goniotomy for corticosteroid-induced glaucoma and to provide evidence to support its use as initial surgical therapy.

Methods:
The medical records of 5 patients with a history of goniosurgery for steroid-induced glaucoma were reviewed. Preoperative and postoperative clinical findings were reviewed, including the topical use of steroids, tonometric and gonioscopic findings, goniosurgery, and postoperative results. In addition, tonography was performed on one patient to document the improved facility of outflow following successful goniosurgery.

Results:

Surgical success was achieved in all patients, with intraocular pressures less than 18 mm Hg without the use of medication for an average follow-up period of 11.5 years (range: 9 months to 30 years). A normal postoperative facility of outflow (C = 0.30 mm
3
/min/mm Hg) was determined in one patient. No complications of surgery were experienced.

Conclusion:
Goniotomy is an effective procedure for persistent steroid-induced glaucoma, and should be considered for initial surgical treatment.

[
J Pediatr Ophthalmol Strabismus.
2015;52(3):183–188.]
Comparison of the Efficacy of Medial Rectus Recession and Lateral Rectus Resection for Treatment of Divergence Insufficiency
Authors: Breidenstein Brenda G. , Robbins Shira L. , Granet David B. , Acera Erika C. 
Published: June 2015

Purpose:
Surgical approaches for divergence insufficiency esotropia include medial rectus recession and lateral rectus resection. A retrospective chart review compared the efficacy of each.

Methods:
Eighteen patients older than 50 years with divergence insufficiency esotropia who were operated on between 2005 and 2012 by two surgeons were reviewed.

Results:

Nine patients underwent medial rectus recession and nine underwent lateral rectus resection. The average distance esotropia decreased from 19.75 to 3.2 prism diopters in the medial rectus recession group (
P
= .001) and from 17.7 to 2.6 prism diopters in the lateral rectus resection group (
P
= .0002). The disparity between distance and near alignment decreased from 7.3 to 3.4 in the medial rectus recession group (
P
= .019) and from 9 to 5.4 prism diopters in the lateral rectus resection group (
P
= .004).

Conclusions:
Both medial rectus recession and lateral rectus resection are effective treatment for divergence insufficiency, with both decreasing distance-near disparity.

[
J Pediatr Ophthalmol Strabismus.
2015;52(3):173–176.]
Bioinformatics Data Mining Approach Suggests Coexpression of AGTPBP1 with an ALS-linked Gene C9orf72
Authors: Kitano Shouta , Kino Yoshihiro , Yamamoto Yoji , Takitani Mika , Miyoshi Junko , Ishida Tsuyoshi , Saito Yuko , Arima Kunimasa , Satoh Jun-Ichi 
Published: June 2015

BackgroundExpanded GGGGCC hexanucleotide repeats located in the noncoding region of the chromosome 9 open reading frame 72 ( C9orf72) gene represent the most common genetic abnormality for familial and sporadic amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Formation of nuclear RNA foci, accumulation of repeat-associated non-ATG-translated dipeptide-repeat proteins, and haploinsufficiency of C9orf72 are proposed for pathological mechanisms of C9ALS/FTD. However, at present, the physiological function of C9orf72 remains largely unknown.MethodsBy searching on a bioinformatics database named COXPRESdb composed of the comprehensive gene coexpression data, we studied potential C9orf72 interactors.ResultsWe identified the ATP/GTP binding protein 1 ( AGTPBP1) gene alternatively named NNA1 encoding a cytosolic carboxypeptidase whose mutation is causative of the degeneration of Purkinje cells and motor neurons as the most significant gene coexpressed with C9orf72. We verified coexpression and interaction of AGTPBP1 and C9orf72 in transfected cells by immunoprecipitation and in neurons of the human brain by double-labeling immunohistochemistry. Furthermore, we found a positive correlation between AGTPBP1 and C9orf72 mRNA expression levels in the set of 21 human brains examined.ConclusionsThese results suggest that AGTPBP1 serves as a C9orf72 interacting partner that plays a role in the regulation of neuronal function in a coordinated manner within the central nervous system.
Evaluations of tropospheric aerosol properties simulated by the community earth system model with a sectional aerosol microphysics scheme
Authors: Yu Pengfei , Toon Owen B. , Bardeen Charles G. , Mills Michael J. , Fan Tianyi , English Jason M. , Neely Ryan R. 
Published: June 2015

AbstractA sectional aerosol model (CARMA) has been developed and coupled with the Community Earth System Model (CESM1). Aerosol microphysics, radiative properties, and interactions with clouds are simulated in the size‐resolving model. The model described here uses 20 particle size bins for each aerosol component including freshly nucleated sulfate particles, as well as mixed particles containing sulfate, primary organics, black carbon, dust, and sea salt. The model also includes five types of bulk secondary organic aerosols with four volatility bins. The overall cost of CESM1‐CARMA is approximately ∼2.6 times as much computer time as the standard three‐mode aerosol model in CESM1 (CESM1‐MAM3) and twice as much computer time as the seven‐mode aerosol model in CESM1 (CESM1‐MAM7) using similar gas phase chemistry codes. Aerosol spatial‐temporal distributions are simulated and compared with a large set of observations from satellites, ground‐based measurements, and airborne field campaigns. Simulated annual average aerosol optical depths are lower than MODIS/MISR satellite observations and AERONET observations by ∼32%. This difference is within the uncertainty of the satellite observations. CESM1/CARMA reproduces sulfate aerosol mass within 8%, organic aerosol mass within 20%, and black carbon aerosol mass within 50% compared with a multiyear average of the IMPROVE/EPA data over United States, but differences vary considerably at individual locations. Other data sets show similar levels of comparison with model simulations. The model suggests that in addition to sulfate, organic aerosols also significantly contribute to aerosol mass in the tropical UTLS, which is consistent with limited data.
Fusobacteriia class. nov.
Authors: Staley James T. , Whitman William B. 
Published: June 2015

Fu.so.bac.te'ri.ia. N L. neut. n.
Fusobacterium
type genus of the order
Fusobacteriales
; suff. ‐
ia
ending proposed by Gibbons and Murray and by Stackebrandt et al. to denote class; N.L. neut. pl. n.
Fusobacteriia
the
Fusobacterium
class.

Fusobacteria	/ Fusobacteriia
Intraskeletal Variability of Relative Cortical Area in Humans
Authors: Stewart Marissa C. , Goliath Jesse R. , Stout Sam D. , Hubbe Mark 
Published: June 2015

ABSTRACTHistomorphometric and cross‐sectional geometric studies of bone have provided valuable information about age at death, behavioral and activity patterns, and pathological conditions for past and present human populations. While a considerable amount of exploratory and applied research has been completed using histomorphometric and cross‐sectional geometric properties, the effects of intraskeletal variability on interpreting observed histomorphometric data have not been fully explored. The purpose of this study is to quantify intraskeletal variability in the relative cortical area of long bones and ribs from modern humans. To examine intraskeletal variability, cross‐sections of the femur, tibia, fibula, humerus, radius, ulna, and rib when present, were examined within individuals from a cadaveric collection (N = 34). Relative cortical area was compared within individuals using a repeated measurements General Linear Model, which shows significant differences between bones, particularly between the rib and the remaining long bones. Complementarily, correlations between bones’ relative cortical area values suggest an important allometric component affecting this aspect of long bones, but not of the rib. This study highlights the magnitude of intraskeletal variability in relative cortical area in the human skeleton, and because the relative cortical area of any particular bone is affected by a series of confounding factors, extrapolation of relative cortical area values to infer load history for other skeletal elements can be misleading. Anat Rec, 298:1635–1643, 2015. © 2015 Wiley Periodicals, Inc.
Ammonia‐based intermittent aeration control optimized for efficient nitrogen removal
Authors: Regmi Pusker , Bunce Ryder , Miller Mark W. , Park Hongkeun , Chandran Kartik , Wett Bernhard , Murthy Sudhir , Bott Charles B. 
Published: June 2015

ABSTRACTThis work describes the development of an intermittently aerated pilot‐scale process (V = 0.45 m3) operated for optimized efficient nitrogen removal in terms of volume, supplemental carbon and alkalinity requirements. The intermittent aeration pattern was controlled using a strategy based on effluent ammonia concentration set‐points. The unique feature of the ammonia‐based aeration control was that a fixed dissolved oxygen (DO) set‐point was used and the length of the aerobic and anoxic time (anoxic time ≥25% of total cycle time) were changed based on the effluent ammonia concentration. Unlike continuously aerated ammonia‐based aeration control strategies, this approach offered control over the aerobic solids retention time (SRT) to deal with fluctuating ammonia loading without solely relying on changes to the total SRT. This approach allowed the system to be operated at a total SRT with a small safety factor. The benefits of operating at an aggressive SRT were reduced hydraulic retention time (HRT) for nitrogen removal. As a result of such an operation, nitrite oxidizing bacteria (NOB) out‐selection was also obtained (ammonia oxidizing bacteria [AOB] maximum activity: 400 ± 79 mgN/L/d, NOB maximum activity: 257 ± 133 mgN/L/d, P < 0.001) expanding opportunities for short‐cut nitrogen removal. The pilot demonstrated a total inorganic nitrogen (TIN) removal rate of 95 ± 30 mgN/L/d at an influent chemical oxygen demand: ammonia (COD/NH4+‐N) ratio of 10.2 ± 2.2 at 25°C within the hydraulic retention time (HRT) of 4 h and within a total SRT of 5–10 days. The TIN removal efficiency up to 91% was observed during the study, while effluent TIN was 9.6 ± 4.4 mgN/L. Therefore, this pilot‐scale study demonstrates that application of the proposed on‐line aeration control is capable of relatively high nitrogen removal without supplemental carbon and alkalinity addition at a low HRT. Biotechnol. Bioeng. 2015;112: 2060–2067. © 2015 Wiley Periodicals, Inc.
Guest Editorial: The Professional Status of European Chemists and Chemical Engineers
Authors: Salzer Reiner , Taylor Philip , Majcen Nineta H. , De Angelis Francesco , Wilmet Sophie , Varella Evangelia , Kozaris Ioannis 
Published: June 2015

AbstractWhich country pays its chemists and chemical engineers the highest salaries? Where can I find a new job quickest? Which chemical sub‐discipline offers most jobs? Reliable answers for these and other questions have been derived from the first European employment survey for chemists and chemical engineers, which was carried out in 2013. Here we publish the first general evaluation of the results of this survey.
Diagenetic incorporation of Sr into aragonitic bivalve shells: implications for chronostratigraphic and palaeoenvironmental interpretations
Authors: Marcano Maria C. , Frank Tracy D. , Mukasa Samuel B. , Lohmann Kyger C , Taviani Marco 
Published: June 2015

AbstractAragonite is easily altered during diagenesis, therefore presumed pristine when present. In effect, beyond polymorphic transformation to calcite, alteration paths of aragonite remain poorly understood despite heavy reliance on such material to produce palaeoenvironmental and chronostratigraphic interpretations. Previous work on core material from Southern McMurdo Sound, Antarctica, showed that unlike their calcitic counterparts, seemingly unaltered aragonite shell fragments invariably produced older than expected 87Sr/86Sr ages. In this study, we pursued additional analyses of these aragonite shells and of the porewater of the core to understand this discrepancy. Aragonite mineralogy was reconfirmed and elemental mapping of shell fragments revealed growth lines within the middle layer suggestive of good preservation. The outer layer, however, showed anomalously high Sr concentrations (average 4·5 ± 0·6 mole% SrCO3; ca 25 mmol mol−1 Sr/Ca) and was depleted in 18O and 13C compared to the middle layer, both features inconsistent with pristine material. The δ18O values and Sr concentrations of the porewater were used to model outer layer compositions reasonably well. Coincidentally, porewater Sr isotope composition was in general agreement with the age model of the core only at the aragonite‐bearing interval suggesting that Sr‐isotopic disequilibrium between porewater and the carbonates was the rule rather than the exception in the core. The Sr isotope compositions of the aragonite shells are most likely the result of early diagenesis as suggested by the inconsistent O and C isotope compositions between shell layers and the anomalously high Sr concentrations. We conclude that knowledge of Sr concentration and distribution in shells is critical to determine the viability of Sr stratigraphy and the scale at which it may be applied. Reliance on traditional indicators of lack of alteration, such as cathodoluminescence, Mn‐Fe concentration, and the presence of labile mineralogies to assert chronostratigraphic and palaeoenvironmental questions may produce erroneous conclusions due to obscurely altered material.
Species sensitivity weighted distribution for ecological risk assessment of engineered nanomaterials: The n-TiO2 case study
Authors: Semenzin Elena , Lanzellotto Elisa , Hristozov Danail , Critto Andrea , Zabeo Alex , Giubilato Elisa , Marcomini Antonio 
Published: June 2015

Abstract

Societal concerns about the environmental risks of engineered nanomaterials (ENMs) have recently increased, but nano-ecological risk assessments are constrained by significant gaps in basic information on long-term effects and exposures, for example. An approach to the ecological risk assessment of ENMs is proposed that can operate in the context of high uncertainty. This approach further develops species sensitivity weighted distribution (SSWD) by including 3 weighting criteria (species relevance, trophic level abundance, and nanotoxicity data quality) to address nano-specific needs (n-SSWD). The application of n-SSWD is illustrated for nanoscale titanium dioxide (n-TiO2), which is available in different crystal forms; it was selected because of its widespread use in consumer products (e.g., cosmetics) and the ample availability of data from ecotoxicological studies in the literature (including endpoints for algae, invertebrates, bacteria, and vertebrates in freshwater, saltwater, and terrestrial compartments). The n-SSWD application resulted in estimation of environmental quality criteria (hazard concentration affecting 5% and 50% of the species) and ecological risk (potentially affected fraction of species), which were then compared with similar results obtained by applying the traditional species sensitivity distribution (SSD) approach to the same dataset. The n-SSWDs were also built for specific trophic levels (e.g., primary producers) and taxonomic groups (e.g., algae), which helped to identify the most sensitive organisms. These results showd that n-SSWD is a valuable risk tool, although further testing is suggested. Environ Toxicol Chem 2015;34:2644–2659. © 2015 SETAC
The Leukemia Inhibitory Factor Receptor Gene Is a Direct Target of RUNX1
Authors: Qadi Abeer A. , Taberlay Phillippa C. , Phillips Jessica L. , Young Arabella , West Alison C. , Brettingham‐Moore Kate H. , Dickinson Joanne L. , Holloway Adele F. 
Published: June 2015

ABSTRACTActivation of cytokine signaling via the leukemia inhibitory factor receptor (LIFR) plays an integral role in hematopoiesis, osteogenesis, and placental development, along with mediating neurotrophic mechanisms. However, the regulatory control of the LIFR gene has remained largely unexplored. Here, we characterize the LIFR gene as a novel target of the RUNX1 transcription factor. The RUNX1 transcription factor is an essential regulator of hematopoiesis and is a frequent target of point mutations and chromosomal alterations in leukemia. RUNX1 regulates hematopoiesis through its control of genes important for hematopoietic cell growth, proliferation, and differentiation, including a number of cytokines and cytokine receptors. LIFR is regulated by two alternate promoters: a placental‐specific and a ubiquitously active general promoter. We show that both of these promoters are regulated by RUNX1. However, in myeloid cells LIFR expression is driven solely by the general LIFR promoter with our data indicating that the placental promoter is epigenetically silenced in these cells. While RUNX1 activates the LIFR general promoter, the oncogenic RUNX1‐ETO fusion protein generated by the t(8;21) translocation commonly associated with acute myeloid leukemia represses promoter activity. The data presented here establish LIFR as a transcriptional target of RUNX1 and suggest that disruption of RUNX1 activity in myeloid cells may result in altered LIFR signaling in these cells. J. Cell. Biochem. 117: 49–58, 2016. © 2015 Wiley Periodicals, Inc.