bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Needle Age and Location on the Volatile Composition of Essential Oils from Juniperus communis L.: A Chemometric Study
Authors: Tobolková Blanka , Panghyová Lenka , Dimitrov Filip , Vargová Vladimíra , Jančová Mariana , Kopuncová Mária , Baxa Stanislav , Polovka Martin 
Published: June 2024

AbstractProfiles of the volatile organic compound (VOC) content of essential oils (EOs) extracted from young and old Juniperus communis L. needles were generated via gas chromatography combined with mass spectrometry (GC‐MS) and flame ionization detection (GC‐FID) and subsequently processed using multivariate statistical methods. These were then used to differentiate the EOs according to needle age and geographical origin. From a total 49 of VOCs identified, statistically significant differences (p<0.05) between young‐ and old‐needle EOs were found for 21 VOCs. Most of the EOs from the young needles showed higher (p<0.05) contents of α‐ and β‐pinene and sesquiterpenes (β‐ and γ‐elemene, germacrene D and B, α‐muurolene, and δ‐cadinene) and their oxygenated derivatives (α‐ and τ‐cadinol), while most of the monoterpenes (α‐thujene, sabinene, terpinolene, β‐myrcene, β‐phellandrene, and p‐cymene) were present in higher quantities (p<0.05) in the EOs from the old needles. The volatiles germacrene D, α‐ and β‐pinene, α‐cadinol, and sabinene were identified via stepwise and canonical discriminant analysis as the most valuable for EO discrimination according to needle age and geographical origin. Recognition and prediction ability tests of the EOs achieved 100 % accuracy in EO classification according to the above mentioned criterion.
Photoreceptor‐Mimetic Microflowers for Restoring Light Responses in Degenerative Retina through a 2D Nanopetal/Cell Biointerface
Authors: Oudeng Gerile , Banerjee Seema , Wang Qin , Jiang Ding , Fan Yadi , Wu Honglian , Pan Feng , Yang Mo 
Published: June 2024

AbstractRetinitis pigmentosa is the main cause of inherited human blindness and is associated with dysfunctional photoreceptors (PRs). Compared with traditional methods, optoelectronic stimulation can better preserve the structural integrity and genetic content of the retina. However, enhancing the spatiotemporal accuracy of stimulation is challenging. Quantum dot‐doped ZnIn2S4 microflowers (MF) are utilized to construct a biomimetic photoelectric interface with a 0D/3D heterostructure, aiming to restore the light response in PR‐degenerative mice. The MF bio interface has dimensions similar to those of natural PRs and can be distributed within the curved spatial region of the retina, mimicking cellular dispersion. The soft 2D nano petals of the MF provide a large specific surface area for photoelectric activation and simulate the flexibility interfacing between cells. This bio interface can selectively restore the light responses of seven types of retina ganglion cells that encode brightness. The distribution of responsive cells forms a pattern similar to that of normal mice, which may reflect the generation of the initial “neural code” in the degenerative retina. Patch‐clamp recordings indicate that the bio interface can induce spiking and postsynaptic currents at the single‐neuron level. The results will shed light on the development of a potential bionic subretinal prosthetic toolkit for visual function restoration.
Tunable and Non‐Invasive Printing of Transmissive Interference Colors with 2D Material Inks
Authors: Liu Jiarong , Huang Ziyang , Xu Youan , Liu Peng , Wu Keyou , Hao Yugan , Zhang Yunhao , Zhang Zhiyuan , Zhang Zehao , Ding Baofu , Li Bing , Liu Bilu 
Published: June 2024

AbstractInterference colors hold significant importance in optics and arts. Current methods for printing interference colors entail complex procedures and large‐scale printing systems for the scarcity of inks that exhibit both sensitivity and tunability to external fields. The production of highly transparent inks capable of rendering transmissive colors has presented ongoing challenges. Here, a type of paramagnetic ink based on 2D materials that exhibit polychrome in one magnetic field is invented. By precisely manipulating the doping ratio of magnetic elements within titanate nanosheets, the magneto‐optical sensitivity named Cotton–Mouton coefficient is engineerable from 728 to a record high value of 3272 m−1 T−2, with negligible influence on its intrinsic wide optical bandgap. Combined with the sensitive and controllable magneto‐responsiveness of the ink, modulate and non‐invasively print transmissive interference colors using small permanent magnets are precised. This work paves the way for preparing transmissive interference colors in an energy‐saving and damage‐free manner, which can expand its use in widespread areas.
The challenges and breakthroughs in the development of diagnostic monoclonal antibodies
Authors: Wang Jing , Song Qitao , Yang Tao , Li Yuanli , Zhang Lihua , Li Jiayan , Liu Feifei , Lin Yanyin , Xu Xiaoxia , Heng Yu , Xu Lulai , Zhang Shun , Zhou Jiahui , Liu Yunbo , Kong Lingyuan , Tang Dingbin , Ji Chengdong , Tan Bing , Liao Pu , Pan Nengke , Yi Weijing , Wang Zhanhui 
Published: June 2024

AbstractOver the past century, the field of antibody discovery has undergone significant evolution, excluding the current exploration stage of artificial intelligence‐based antibody generation and the often overlooked non‐animal sourced antibody discovery, which typically requires mature in vitro affinity and the selection of high‐quality antigen formulations. This journey has traversed various stages, from methods involving serum‐based antibody acquisition, the isolation of B cells capable of perpetual antibody production through hybridoma technology, to the in‐depth exploration of genetic material using the phage display system, and the current stage involving diverse single B cell screening techniques. Additionally, the emergence of machine learning has brought impressive scientific and technological breakthroughs across research domains, proving to be a powerful application in the field of antibody discovery. However, each technique comes with its limitations, such as variability and control challenges in serum‐based acquisition, lengthy and difficult hybridoma‐derived antibody development, potential limitations in sequence and epitope diversity due to immunization biases in phage display techniques, and costly single B cell screening. Protein mass spectrometry sequencing, with shorter acquisition time and lower costs, is seen as a shortcut by diagnostic companies, impacting traditional antibody development. In diagnostic antibody development, methodological differences in downstream assays and the impact of constant regions outside the Fv core are often neglected. This paper deeply analyzes challenges, proposing innovative strategies for the next generation of diagnostic antibody development. Aimed at moving closer to the gold standard of antibody discovery, these strategies enhance the competitiveness of diagnostic reagent products.
Einleitung
Authors: Voß Julia , Meyer zu Altenschildesche Clara , Ettl Kerstin 
Published: June 2024

Zusammenfassung„Innovatorinnen gestalten Zukunft – Fallstudien für Praxis und Lehre“ illustriert die Rolle von Frauen in Innovationsprozessen und hebt in diesem Zusammenhang die Bedeutung von Diversität und Sichtbarkeit hervor. Angesichts globaler Herausforderungen wie dem Klimawandel und der Ressourcenverknappung betont dieses essential die Notwendigkeit, Innovationspotenziale voll auszuschöpfen. Hierzu bietet es eine Sammlung praxisnaher Fallstudien, die auf realen Beispielen basieren, ein breites Spektrum an Innovationsaspekten abdecken und die Lesenden zur Reflexion des Themas anregen. Jede Fallstudie ist mit einer „Teaching Note“ versehen, die Lernziele, Leitfragen und Literaturhinweise ergänzt, was sie zu einem wertvollen Instrument sowohl in der (akademischen) Lehre als auch in der beruflichen Praxis macht. Die Fallstudiensammlung zielt darauf ab, das Bewusstsein der Lesenden für die Bedeutung von Diversität und Sichtbarkeit in Innovationsprozessen zu schärfen und richtet sich insbesondere an Studierende und Praktiker:innen, die sich für Innovationen, die Beiträge von Innovatorinnen und (Innovations-)Strategien interessieren.
Werte und Wandel in Familienunternehmen
Authors: Voß Julia , Meyer zu Altenschildesche Clara , Ettl Kerstin 
Published: June 2024

ZusammenfassungDie Fallstudie porträtiert Ariane Meisner, die nach dem unerwarteten Ausscheiden ihres Vaters die Führung des langjährigen Familienbetriebs übernimmt und sich als Unternehmensnachfolgerin in einem Industrieunternehmen neben wirtschaftlichen und sozialen Herausforderungen mit einer traditionell geprägten Unternehmenskultur konfrontiert sieht. Unter schwierigen wirtschaftlichen Rahmenbedingungen entwickelt sie neue Ansätze, um das Unternehmen innovativ und effizient aufzustellen. Der Fall zeigt, wie es durch den Einsatz von Prozessinnovationen, Kommunikation und Transparenz gelingen kann, eine bislang traditionell und maskulin geprägte Unternehmenskultur zu verändern und ein mittelständisches Unternehmen nachhaltig erfolgreich aufzustellen.
Technik + Diversität = Vorbild im Wissenschaftskontext?
Authors: Voß Julia , Meyer zu Altenschildesche Clara , Ettl Kerstin 
Published: June 2024

ZusammenfassungDiese Fallstudie erzählt die Geschichte von Amina Kalid, einer leidenschaftlichen Technikliebhaberin mit multikulturellem Hintergrund. Von technischem Fortschritt und Innovation fasziniert, überwindet Amina mit großer Entschlossenheit gängige Stereotype und bahnt sich ihren Weg in einem männlich dominierten Wissenschaftszweig bis hin zur Professur. Mit zunehmendem Erfolg wird Amina eine immer sichtbarere Akteurin in ihrem Betätigungsfeld – Fluch und Segen zugleich. Der Fall beleuchtet die Chancen, Herausforderungen und Erwartungen, die mit erhöhter Sichtbarkeit einhergehen, darunter die Erwartung, als Frau mit Migrationshintergrund in einem männlich dominierten Bereich automatisch als „Diversitätsvorbild“ zu dienen. Zudem wird deutlich, welchen Innovationseinfluss Wissenschaftseinrichtungen ausüben können und wie diese mit anderen Akteuren im Innovationsökosystem zusammenspielen.
Unverzichtbar und dennoch unsichtbar im Unternehmen?
Authors: Voß Julia , Meyer zu Altenschildesche Clara , Ettl Kerstin 
Published: June 2024

ZusammenfassungIn dieser Fallstudie steht Anna Berger im Mittelpunkt, die als Leiterin der Innovationsabteilung bei der GlobalTech Solutions die Unternehmensentwicklung durch unterschiedliche Innovationsprojekte voranbringt. Obwohl Anna eine treibende Kraft hinter den Innovationsbemühungen des Unternehmens ist, werden diese umgesetzt, ohne dass bekannt ist, dass sie die Innovatorin hinter der Innovation ist. Nach außen werden die Neuerungen durch den Unternehmensvorstand repräsentiert. So werden zwar Annas Innovationen sichtbar und wirksam, sie selbst bleibt jedoch unsichtbar. Der Fall zeichnet gängige Geschlechterdynamiken im Innovationsprozess nach und wie diese zur Unsichtbarkeit von Innovator:innen im Besonderen und von Frauen in Führungspositionen im Allgemeinen führen können. So wird die Frage aufgeworfen, wie Organisationen sicherstellen können, dass Anerkennung nicht nur den sichtbaren Produkten, sondern auch anderen Innovationsformen und den Innovator:innen selbst zuteilwerden kann.
On amplitudes and field redefinitions
Authors: Cohen Timothy , Lu Xiaochuan , Sutherland Dave 
Published: June 2024

Abstract
We derive an off-shell recursion relation for correlators that holds at all loop orders. This allows us to prove how generalized amplitudes transform under generic field redefinitions, starting from an assumed behavior of the one-particle-irreducible effective action. The form of the recursion relation resembles the operation of raising the rank of a tensor by acting with a covariant derivative. This inspires a geometric interpretation, whose features and flaws we investigate.
The flavor of a minimal composite S1 leptoquark and the $$ b\to c\tau \overline{\nu} $$ anomaly
Authors: Da Rold Leandro 
Published: June 2024

Abstract
Several experiments have measured a deviation in B → D(∗) semileptonic decays, that point to new physics at the TeV scale violating lepton flavor universality. A scalar leptoquark S1, with a suitable structure of couplings in flavor space, is known to be able to solve this anomaly modifying $$ b\to c\tau \overline{\nu} $$
b
→
cτ

ν
¯

. In the context of composite Higgs models, we consider a theory containing H and S1 as Nambu-Goldstone bosons (NGBs) of a new strongly interacting sector, with ordinary resonances at a scale $$ \mathcal{O}(10) $$
O

10

TeV. Assuming anarchic partial compositeness of the Standard Model (SM) fermions we calculate the potential of the NGBs that is dominated by the fermions of the third generation, we compute $$ {R}_{D^{\left(\ast \right)}} $$

R

D

∗

and estimate the corrections to flavor observables by the presence of S1. We find that the SM spectrum and $$ {m}_{S_1} $$

m

S
1

∼ TeV can be obtained with a NGB decay constant of order ∼ 5 TeV. We obtain a robust correlation between the main corrections to $$ {R}_{D^{\left(\ast \right)}} $$

R

D

∗

, $$ {B}_{K^{\left(\ast \right)}\nu \nu} $$

B

K

∗

νν

and gτ/gμ, that leads to a sever bound on $$ {R}_{D^{\left(\ast \right)}} $$

R

D

∗

, roughly 2σ below the experimental value. Besides the bounds on the flavor observables $$ {g}_{\tau}^W $$

g
τ
W

, BR(τ → μγ) and $$ \Delta {m}_{B_s} $$
∆

m

B
s

are saturated, with the first one requiring a coupling between resonances g* ≲ 2, whereas the second one demands $$ {m}_{S_1} $$

m

S
1

≳ 1.7 TeV, up to corrections of $$ \mathcal{O}(1) $$
O

1

.
Inclusive semileptonic $$ {B}_s^0 $$ meson decays at the LHC via a sum-of-exclusive modes technique: possibilities and prospects
Authors: De Cian M. , Feliks N. , Rotondo M. , Vos K. Keri 
Published: June 2024

Abstract
We propose an approach for measuring the moments of the hadronic invariant mass distribution in semileptonic $$ {B}_s^0 $$

B
s
0

meson decays using a sum-of-exclusive technique. Using the present and foreseen knowledge about exclusive semileptonic $$ {B}_s^0 $$

B
s
0

decays, we estimate the uncertainties on moments of the kinematic distribution. Semileptonic $$ {B}_s^0 $$

B
s
0

decays can be described, as their B0 counterpart, using the Heavy Quark Expansion (HQE), with the only difference between the $$ {B}_s^0 $$

B
s
0

and B0 mesons being the SU(3)F breaking effects that change the numerical values of the non-perturbative HQE parameters. We extract the HQE parameters for the $$ {B}_s^0 $$

B
s
0

decays from our estimates of the moments, showing the potential of the proposed method. We identify a set of required measurements for a future precision measurement.
Cluster Scanning: a novel approach to resonance searches
Authors: Oleksiyuk I. , Raine J. A. , Krämer M. , Voloshynovskiy S. , Golling T. 
Published: June 2024

Abstract
We propose a new model-independent method for new physics searches called Cluster Scanning. It uses the k-means algorithm to perform clustering in the space of low-level event or jet observables, and separates potentially anomalous clusters to construct a signal-enriched region. The spectra of a selected observable (e.g. invariant mass) in these two regions are then used to determine whether a resonant signal is present. A pseudo-analysis on the LHC Olympics dataset with a Z′ resonance shows that Cluster Scanning outperforms the widely used 4-parameter functional background fitting procedures, reducing the number of signal events needed to reach a 3σ significant excess by a factor of 0.61. Emphasis is placed on the speed of the method, which allows the test statistic to be calibrated on synthetic data.
Dark matter semi-annihilation for inert scalar multiplets
Authors: Beauchesne Hugues , Chiang Cheng-Wei 
Published: June 2024

Abstract
Dark matter semi-annihilation is a process through which two dark matter candidates annihilate to a single dark matter particle and a non-dark matter particle. Such processes are common when the symmetry stabilizing the dark matter differs from ℤ2 and can lead to qualitatively different phenomenology. In this work, we study the viability of semi-annihilation models including one or two inert multiplets. For one multiplet, we show that there does not exist any viable model in which semi-annihilation is efficient. For two multiplets, semi-annihilation can be efficient, but the number of viable and technically natural models is limited. We then perform a detailed study of the most promising model, showing that the correct relic abundance can be obtained for a wide range of masses.
Integrated correlators at strong coupling in an orbifold of $$ \mathcal{N} $$ = 4 SYM
Authors: Pini Alessandro , Vallarino Paolo 
Published: June 2024

Abstract
We consider the 4d$$ \mathcal{N} $$
N
= 2 superconformal quiver gauge theory obtained by a ℤ2 orbifold of $$ \mathcal{N} $$
N
= 4 super Yang-Mills (SYM). By exploiting supersymmetric localization, we study the integrated correlator of two Coulomb branch and two moment map operators and the integrated correlator of four moment map operators, determining exact expressions valid for any value of the ’t Hooft coupling in the planar limit. Additionally, for the second correlator, we obtain an exact expression also for the next-to-planar contribution. Then, we derive the leading terms of their strong-coupling expansions and outline the differences with respect to the $$ \mathcal{N} $$
N
= 4 SYM theory.
Perturbative approach to time-dependent quantum solitons
Authors: Ogundipe Kehinde , Evslin Jarah 
Published: June 2024

Abstract
Recently we have introduced a lightweight, perturbative approach to quantum solitons. Thus far, our approach has been largely limited to configurations consisting of a single soliton plus a finite number of mesons, whose classical limit is an isolated stationary or rigidly moving soliton. In this paper, with an eye to soliton collisions and oscillons, we generalize this approach to quantum states whose classical limits are genuinely time-dependent. More precisely, we use a unitary operator, inspired by the coherent state approach to solitons, to factor out the nonperturbative part of the state, which includes the classical motion. The solution for the quantum state and its evolution is then reduced to an entirely perturbative problem.
Effective field theories on subspaces of the Bruhat-Tits tree
Authors: Qu Feng 
Published: June 2024

Abstract
On two subspaces of the Bruhat-Tits tree, effective actions are calculated. The limits of these effective field theories are found to be the same conformal field theory over p-adic numbers when subspaces are taken to the boundary of the tree. Their relations to the p-adic version of AdS/CFT are also discussed.
Influencing factors for delayed diagnosed injuries in multiple trauma patients – introducing the ‘Risk for Delayed Diagnoses Score’ (RIDD-Score)
Authors: Gümbel Denis , Matthes Gerrit , Ekkernkamp Axel , Laue Fabian , Lefering Rolf ,   The TraumaRegister DGU
Published: June 2024

Abstract
Purpose
Delayed diagnosed injuries (DDI) in severely injured patients are an essential problem faced by emergency staff. Aim of the current study was to analyse incidence and type of DDI in a large trauma cohort. Furthermore, factors predicting DDI were investigated to create a score to identify patients at risk for DDI.

Methods
Multiply injured patients admitted between 2011 and 2020 and documented in the TraumaRegister DGU® were analysed. Primary admitted patients with severe injuries and/or intensive care who survived at least 24 h were included. The prevalence, type and severity of DDI were described. Through multivariate logistic regression analysis, risk factors for DDI were identified. Results were used to create a ‘Risk for Delayed Diagnoses’ (RIDD) score.

Results
Of 99,754 multiply injured patients, 9,175 (9.2%) had 13,226 injuries first diagnosed on ICU. Most common DDI were head injuries (35.8%), extremity injuries (33.3%) and thoracic injuries (19.7%). Patients with DDI had a higher ISS, were more frequently unconscious, in shock, required more blood transfusions, and stayed longer on ICU and in hospital. Multivariate analysis identified seven factors indicating a higher risk for DDI (OR from 1.2 to 1.9). The sum of these factors gives the RIDD score, which expresses the individual risk for a DDI ranging from 3.6% (0 points) to 24.8% (6 + points).

Conclusion
DDI are present in a sounding number of trauma patients. The reported results highlight the importance of a highly suspicious and thorough physical examination in the trauma room. The introduced RIDD score might help to identify patients at high risk for DDI. A tertiary survey should be implemented to minimise delayed diagnosed or even missed injuries.
Major cardiovascular events and death in parents of children with type 1 diabetes: a register-based matched cohort study in Sweden
Authors: Kennedy Beatrice , Wernroth Mona-Lisa , Batra Gorav , Hammar Ulf , Linroth Cecilia , Grönberg Annika , Byberg Liisa , Fall Tove 
Published: June 2024

Abstract
Aims/hypothesis
Parenting a child with type 1 diabetes has been associated with stress-related symptoms. This study aimed to elucidate the potential impact on parental risk of major cardiovascular events (MCE) and death.

Methods
In this register-based study, we included the parents of 18,871 children, born 1987–2020 and diagnosed with type 1 diabetes in Sweden at <18 years. The median parental age at the child's diagnosis was 39.0 and 41.0 years for mothers and fathers, respectively. The cohort also encompassed 714,970 population-based matched parental control participants and 12,497 parental siblings. Cox proportional hazard regression models were employed to investigate the associations between having a child with type 1 diabetes and incident MCE and all-cause death, and, as secondary outcomes, acute coronary syndrome and ischaemic heart disease (IHD). We adjusted for potential confounders including parental type 1 diabetes and country of birth.

Results
During follow-up (median 12 years, range 0–35), we detected no associations between parenting a child with type 1 diabetes and MCE in mothers (adjusted HR [aHR] 1.02; 95% CI 0.90, 1.15) or in fathers (aHR 1.01; 95% CI 0.94, 1.08). We noted an increased hazard of IHD in exposed mothers (aHR 1.21; 95% CI 1.05, 1.41) with no corresponding signal in fathers (aHR 0.97; 95% CI 0.89, 1.05). Parental sibling analysis did not confirm the association in exposed mothers (aHR 1.01; 95% CI 0.73, 1.41). We further observed a slightly increased hazard of all-cause death in exposed fathers (aHR 1.09; 95% CI 1.01, 1.18), with a similar but non-significant estimate noted in exposed mothers (aHR 1.07; 95% CI 0.96, 1.20). The estimates from the sibling analyses of all-cause death in fathers and mothers were 1.12 (95% CI 0.90, 1.38) and 0.73 (95% CI 0.55, 0.96), respectively.

Conclusions/interpretation
Having a child diagnosed with type 1 diabetes in Sweden was not associated with MCE, but possibly with all-cause mortality. Further studies are needed to disentangle potential underlying mechanisms, and to investigate parental health outcomes across the full lifespan.

Graphical Abstract