bluuebunny/crossref_metadata_2025_split huggingface dataset:
Operationalizing the Learning Health Care System in an Integrated Delivery
System
Authors: Psek Wayne A. , Stametz Rebecca A. , Bailey-Davis Lisa D. , Davis Daniel , Darer Jonathan , Faucett William A. , Henninger Debra L. , Sellers Dorothy C. , Gerrity Gloria 
Published: March 2015

Introduction: The Learning Health Care System (LHCS) model seeks to utilize
sophisticated technologies and competencies to integrate clinical operations, research
and patient participation in order to continuously generate knowledge, improve care, and
deliver value. Transitioning from concept to practical application of an LHCS presents
many challenges but can yield opportunities for continuous improvement. There is limited
literature and practical experience available in operationalizing the LHCS in the
context of an integrated health system. At Geisinger Health System (GHS) a
multi-stakeholder group is undertaking to enhance organizational learning and develop a
plan for operationalizing the LHCS system-wide. We present a framework for
operationalizing continuous learning across an integrated delivery system and lessons
learned through the ongoing planning process.Framework: The framework focuses attention
on nine key LHCS operational components: Data and Analytics; People and Partnerships;
Patient and Family Engagement; Ethics and Oversight; Evaluation and Methodology;
Funding; Organization; Prioritization; and Deliverables. Definitions, key elements and
examples for each are presented. The framework is purposefully broad for application
across different organizational contexts.Conclusion: A realistic assessment of the
culture, resources and capabilities of the organization related to learning is critical
to defining the scope of operationalization. Engaging patients in clinical care and
discovery, including quality improvement and comparative effectiveness research,
requires a defensible ethical framework that undergirds a system of strong but flexible
oversight. Leadership support is imperative for advancement of the LHCS model. Findings
from our ongoing work within the proposed framework may inform other organizations
considering a transition to an LHCS.
‘Transatlantic connection’: K-pop and K-drama fandom in Spain and Latin America
Authors: Madrid-Morales Dani , Lovric Bruno 
Published: March 2015

Abstract
The global circulation of Asian cultural products has been on a constant rise since the 1990s. However, the arrival to Spanish-speaking audiences is a more recent phenomenon, one that is linked to the consolidation of web-based tools for consumption, distribution and discussion of cultural artefacts. The different stages in which Hallyu, or the ‘Korean Wave’, reached different countries determined the intensity of scholarly interest in the phenomenon. If the research gap between Asia and Europe is wide, the later arrival to Spain and Latin America means that studies on the reception of Korean popular culture, including those dealing with fandom, are quasi-non-existent. This article is a first attempt at mapping the demographics of K-pop and K-drama fans in the Spanish-speaking world, through an analysis of an online survey. Drawing from the uses and gratifications approach in mass communication research, we discuss fans’ appropriation of K-pop, describe their shared iconography and analyse the peculiarities of male fans by studying their self-narratives. We conclude with a discussion on the need for studies of fandom to transcend national boundaries as exemplified by the advent of a ‘transatlantic connection’ linking fans in Spain and in Latin America via South Korea.
Queering spectatorship in K-pop: The androgynous male dancing body and western female fandom
Authors: Oh Chuyun 
Published: March 2015

Abstract
Employing performance studies and queer studies, this article explores the subversive nature of western female fandom’s consumption of male dancing bodies in Korean pop (K-pop) culture. By offering close readings of fan-made compilation videos and analysing fans’ comments on YouTube, this article analyses how K-pop male idols’ androgynous gender fluidity provides a space for queering female desire against normative white masculinity. Through video editing, fans ‘choreograph’ their desire by fetishizing K-pop male dancers’ specific body parts and movements and transform themselves from displayed objects to subjects of the gaze. Moreover, through active engagement online, fans transcend their status from spectators to performers who actively enact alternative sexualities and gender roles in a public space. K-pop male singers’ gender performativity is significant, as it challenges rigid gender binaries in western culture – homosexuality/heterosexuality, masculine/feminine body and behaviour, and masculinized gaze/feminized object – as embodiments of hybridized male femininity, which this article calls liminal masculinity.
Reshaped, reconnected and redefined: Media portrayals of Korean pop idol fandom in Korea
Authors: Kim Ju Oak 
Published: March 2015

Abstract
This article examines how Korean pop (K-pop) idol fans develop their public image through the construction of participatory culture. K-pop idol fans, mostly teenaged girls, have long-provoked criticism in Korean society due to their fanatic behaviours. In the late 2000s, however, the transnational popularity of K-pop idol groups encouraged the public to reconsider the negative stereotype of K-pop idol fandom. This social atmosphere is indebted to news journalism, which sheds light on the contribution of fan communities in the K-pop music industry. Donation activities are one of the main items that journalists focus on in covering idol fan communities. Through an analysis of news articles, this article argues that Korean idol fandom strategically employs donation activities in order to reshape stereotypes about idol fandom, reconnect with the public and redefine the notion of idol fandom in Korean society.
From Holy Land to ‘Hallyu Land’: The symbolic journey following the Korean Wave in Israel
Authors: Lyan Irina , Levkowitz Alon 
Published: March 2015

Abstract
The majority of academic literature on Hallyu, or the Korean Wave, focuses on its acceptance in the geographically and culturally proximate societies in Asia and the economically wealthy markets of North America. Very little attention has been given to other regions such as Africa, South America and the Middle East. Thus, looking at the Israeli case study allows us to examine how Korean culture is being accepted in non-Asian, non-western and non-English contexts. The most salient characteristic of Hallyu fans in Israel is that the majority of them have never been to Korea. They experience Korean culture mostly through Korean TV dramas, and fandom itself becomes a cultural journey between the known and the unknown. This journey resembles the practice of pilgrimage, e.g. an emotional exploration of new places accompanied by a deep sense of fulfilment. Korean culture is perceived as an exotic and distant ‘other’. At the same time, this ‘other’ is domesticated by local fan communities and serves as a means to connect one’s own identity with Hallyu’s ‘promised land’. Based on media and discourse analysis, an online survey and interviews with Israeli fans, this article examines the popularity of the Korean Wave in Israel and its impact on Korea’s image among fans. The article also explores the inner world created among fans of the Korean world, the formation of a fan community and their fictional ‘Hallyu Land’.
Acknowledging a ‘Missing History?’
Authors: Doyle Susan 
Published: March 2015

Abstract
A unique grassroots project is under way to write the first-ever textbook on the History of Illustration. The effort, which benefits from a base of over 30 writers internationally, is backed by a consortium of more than 60 educators, researchers, curators and illustration practitioners collaborating under the aegis of the History of Illustration Project (HIP). The volume, now in development with Fairchild Books (a Bloomsbury imprint), evolved initially through an online conversation about the need for more critical assessment of illustration and its history. Many of the points of that debate are detailed in the article that follows. The summary rationale for the HIP textbook (of which I am lead editor) is to expand the art historical investigation of illustration and address its synergistic relationship to history, science, visual culture and literature.
Alchemy, image and text: The waning of alchemy and the decline of visual discourse in the late Renaissance
Authors: Holme Adrian 
Published: March 2015

Abstract
From its obscure origins in antiquity the alchemical tradition enjoyed a late flowering in seventeenth-century Europe with the appointment of alchemists at European Courts and a profusion of alchemical publications within the rapidly expanding output of printed books. Works, such as Michael Maier’s Atalanta fugiens (1618) and Robert Fludd’s Utriusque cosmi (1617, 1621) incorporated fine engravings, with imagery that reflected the Renaissance spirit of synthesis, resemblance, analogy and allegory, and the deployment of a widely accepted range of symbols and emblems. Microcosm and Macrocosm, matter and spirit, the human and the scientific were presented by Fludd and others as a unified cosmos, linked by complex systems of analogy and resemblance, within a framework of NeoPlatonism and Christianity. Alchemical literature employed a balance of text and image, in which visual argument, using analogy, resemblance, emblem and allegory, complemented text. The question of why this system gave way, in the late seventeenth century and ensuing Enlightenment to modern scientific and other serious discourse, progressively stripped of images, is discussed with reference to the writings of Francis Bacon, Edmund Burke, Ernst Gombrich, WJT Mitchell and Marshall McLuhan. The enduring influence of alchemy upon visual artists, from William Blake to Yves Klein and Anselm Kiefer, reflects a continuing concern with the integration of the material and the spiritual, and challenges a linguistics-based semiotics as well as an excessively reductionist science.
Illustrating Elizabeth Bennet and Mr Darcy: Jane Austen’s Pride and Prejudice
Authors: Newman Emily L. 
Published: March 2015

Abstract
Throughout the nineteenth century, Jane Austen’s Pride and Prejudice (1813) was repeatedly picked up for publication; however, it was slow to be illustrated. Austen tells the story of the Bennet family, as the five girls in the family come of age and are seeking husbands. Mr Darcy and Elizabeth Bennet become the titular characters, and have inspired millions of readers for them to root for their union. The book, of which the countless film adaptations attest, has found a lasting audience. Through an examination of the publishers and the various artists that worked on the editions, I want to examine how the book epitomized trends in the publishing industry. Key publishers like Richard Bentley and J. M. Dent, hired some of the most important illustrators of the time, including John Gilbert, John Proctor, C. E. Brock, Hugh Thomson and Chris Hammond. Through an examination of the artists and the illustrations, we can begin to examine the popularity of the book and why this endearing novel’s popularity is so lasting. Focusing on characters, fanciful clothing and revelatory conversations, these illustrators contributed to the books’ position as one of the most popular romance novels of the century.
The marks and modes of modernism: The Puffin Picture Books (1940–1965)
Authors: Cory-Wright Harriet 
Published: March 2015

Abstract
Casting a proximate net across concurrent artistic, social and political activity in relation to the Puffin Picture books reveals a cultural codification that structured the creation of the populist, pedagogical and practical print practices that materalise in the books. In framing and forming a greater understanding around the circumstances of conception of the books has formed a complex multiplicity of interior views that at once supports, calibrates and challenges familiar early twentieth-century artistic and cultural narratives.
Behavioral strategies of automated vehicles in critical right of way
situations on intersections
Authors: Stoff Alexander , Winner Hermann 
Published: March 2015

Abstract
This paper analyzes and evaluates alternative options for action and earliest possible dates for intervention for an automated safety
function to avoid or mitigate collisions in priority situations in which the right of way regulations are violated by the crossing road
users. Based on a simulation of the collision avoidance strategies, the potential safety benefits could be predicted.
Bosch's approach toward automated driving
Authors: Becker Jan , Kammel Sören , Pink Oliver , Fausten Michael 
Published: March 2015

Abstract
Advanced driver assistance systems already help drivers reach their destinations safely and more comfortably. Future systems will
evolve from driver assistance over highly automated vehicles to fully automated driving. With an increasing level of automation,
automated functions will reduce the driver's burden more and more, thereby creating space for productivity, communication or
entertainment while driving. In this article we outline our roadmap for future automated vehicles, assess the key challenges for
introduction and give an overview of the major algorithmic components.
Einführungsstrategie des Automatischen Fahrens
Authors: Bartels Arne , Ruchatz Thomas 
Published: March 2015

Zusammenfassung
Dieser Artikel adressiert die klare Definition von Begrifflichkeiten für die unterschiedlichen Stufen der Automatischen Fahrzeugführung. Er illustriert eine stufenweise Einführungsstrategie ausgehend von teilautomatischen Funktionen (Stau- & Park-Assistent), gefolgt von automatischen Funktionen, bei denen sich der Fahrer unter bestimmten Voraussetzungen von der Fahraufgabe abwenden darf (Stau-Chauffeur, Autobahn-Chauffeur). Ebenfalls aufgezeigt werden technische Herausforderungen sowie Status und Weiterarbeit zur Anpassung der rechtlichen Rahmenbedingungen.
Pointwise Computation in an Ill-Posed Spherical Pseudo-Differential Equation
Authors: Pereverzyev Sergei V. , Tkachenko Pavlo 
Published: March 2015

Abstract
In the present paper, we consider the approximation of the solution of an ill-posed spherical pseudo-differential equation at a given point. While the methods for approximating the whole solution are well-studied in Hilbert spaces, such as the space of square-summable functions, the computation of values of the solution at given points is much less studied. This can be explained, in particular, by the fact that for square-summable functions the functional of pointwise evaluation is, in general, not well defined. To overcome this limitation we adjust the regularized least-squares method of An, Chen, Sloan and Womersley [Siam J. Numer. Anal. 50 (2012), no. 3, 1513–1534]
by using a special a posteriori parameter choice rule. We also illustrate our theoretical findings by numerical results for the reconstruction of the solution at a given point.
Evaluation of Genotoxic and Inhibitory Effects of Invasive Weed Wild Poinsettia (Euphorbia heterophylla Linn.) in Sunflower
Authors: Safahani Langeroodi Ali Reza , Dadgar Teena , Kamkar Behnam , Teixeira da Silva Jaime A. 
Published: March 2015

AbstractDetermining the mode of action of allelochemicals is one of the challenging aspects in the allelopathic studies. In this research, the methanolic extracts of wild poinsettia (Euphorbia heterophyllaLinn.) at different concentrations (0, as untreated control, 8%, 12% and 16%) were tested for genotoxic and inhibitor activity on morphological, biochemical and molecular traits of sunflower (Helianthus annuusL.). Seedling emergence was reduced with wild poinsettia leaf extracts in sunflower. Leaf extracts of wild poinsettia decreased chlorophyllaandblevels and consequently the soluble sugar content was proportional to the increase in the concentrations of the leaf leachates. Some changes occurred in random amplification of polymorphic DNA (RAPD) profiles, profiles of protein bands and total soluble protein of germinated treated seed. These included variation in band intensity, loss of bands and appearance of new bands compared with control. Increased concentration of extracts caused increasing the total soluble protein content, decreasing genome template stability (GTS) value and increasing polymorphism values, the results indicated that they were dose dependent. For instance, the highest and lowest amounts of GTS were observed in 8% and 16%, respectively. In a dendrogram constructed based on genetic similarity coefficients, the treatments were grouped into two main clusters: (a) 8%, 12% and 16% dose clustered together and (b) untreated control grouped alone. Also, we concluded that the basis of interaction between plants, like allelopathy, may be related with genotoxic effects.
Knowing the Parasite: Biology and Genetics of Orobanche
Authors: Delavault Philippe 
Published: March 2015

AbstractDue to their forms and colors, parasitic plants are most often considered to be botanical curiosities. However, in some cases, these are proved to be also deadly pests with the capacity to exploit other plants. Among the obligate root parasitic weeds, the holoparasites that are devoid of chlorophyll and thus unable to carry out photosynthesis totally rely on their hosts for their water, mineral, and carbohydrate supplies. Members of the genus Orobanche and Phelipanche, belonging to the Orobanchaceae family (the broomrape family), are thus the final result of this evolutionary transition from autotrophism to heterotrophism. The underlying process of this trophic exploitation, governed by a fine-tuned molecular dialogue between both partners, is an extraordinary example of adaptive plant biology operated by these parasitic organisms in the course of evolution. This transition is associated with remarkable morphological and physiological adaptations, such as the requirement for the seeds to germinate to perceive molecules produced by host roots, the development of a novel organ, the haustorium, which invades host tissues and establishes a physiological continuum between the parasite and the host, the establishment of a sink strength required for translocation of host resources, the loss of photosynthesis, and a reduced leaf and root architecture.
Characterization of technical lignins by NMR spectroscopy: optimization of functional group analysis by 31P NMR spectroscopy
Authors: Korntner Philipp , Sumerskii Ivan , Bacher Markus , Rosenau Thomas , Potthast Antje 
Published: March 2015

Abstract

31P nuclear magnetic resonance (NMR) based on the derivatization reagent 2-chloro-4,4,5,5-tetramethyl-1,3,2-dioxaphospholane is a common approach for the hydroxyl group determination of lignins, but the results are sometimes less reproducible compared to other methods. In the present work, common pitfalls in 31P NMR analysis of kraft lignin (KL) and lignosulfonates (LS) are addressed and the results are compared to those obtained by 1H NMR spectroscopy. Several experimental parameters are revisited in terms of the reliability of the obtained data, such as the choice of relaxation delay, internal standards, and the best solution technique for the 31P NMR analysis of LS. For the first time, 31P NMR data of LS are presented based on a new dissolution protocol. The analytical data of a set of lignins consisting of three KLs, one LS, and one milled wood lignin are presented based on the optimized 31P NMR approach.
Opportunistic feeding by the little yellow-shouldered bat Sturnira lilium (Phyllostomidae, Stenodermatinae) in northern Guatemala: a comparative approach
Authors: Kraker-Castañeda Cristian , Cajas-Castillo José Octavio , Lou Salvador 
Published: March 2015

AbstractDuring simultaneous surveys in northern Guatemala, we studied the feeding habits of frugivorous bats. We found that
Serum tryptophan, kynurenine, phenylalanine, tyrosine and neopterin concentrations in 100 healthy blood donors
Authors: Geisler Simon , Mayersbach Peter , Becker Kathrin , Schennach Harald , Fuchs Dietmar , Gostner Johanna M. 
Published: March 2015

Abstract
Formation of neopterin, a biomarker of the activated human immune system, is linked with tryptophan (TRP) and phenylalanine (PHE) metabolism. To obtain normal values, in this study, serum concentrations of neopterin as well as of TRP, PHE and their respective metabolites kynurenine (KYN) and tyrosine (TYR) were investigated in 100 successive blood donor serum specimens from the University Clinics of Innsbruck, Austria. In addition, nitrite concentrations were determined. Donors had passed anamnestic examination at entry and were therefore considered as healthy. The mean age of participants was 49±11.4 (mean±SD) years; 18% were older than 60 years. Both genders were included in the analysis. Neopterin concentrations measured by enzyme-linked immunosorbent assay were 5.9±1.6 nmol/L (mean±SD). Levels of amino acids and metabolites were determined by HPLC. Mean KYN and TRP concentrations were 1.78±0.42 μmol/L and 67.4±10.2 μmol/L, respectively. KYN to TRP ratio (KYN/TRP), an estimate for the activity of tryptophan-degrading enzyme indoleamine 2,3-dioxygenase, was 26.7±6.2 μmol/mmol. Mean PHE and TYR concentrations were 65.2±11.1 μmol/L and 90.6±22.9 μmol/L. PHE to TYR ratio (PHE/TYR), an estimate for the activity of PHE-converting enzyme phenylalanine hydroxylase, was 0.75±0.14 μmol/μmol. Nitrite concentrations, estimated by Griess-Ilosvay reagent, were 44.9±32.0 μmol/L. Males were taller and heavier than females (both p<0.01), but body mass index did not differ. Males presented with significantly higher TRP and TYR concentrations than females (both p<0.05). There existed significant correlations between neopterin and KYN (rs=0.368), KYN/TRP (rs=0.453), TYR (rs=–0.267; all p<0.01) and PHE/TYR (rs=0.236; p<0.05) concentrations. Data indicate that also in a population of healthy individuals an association exists between “low-grade” immune activation as is indicated by slightly higher neopterin concentrations and biochemical alterations in the amino acid metabolism. Although minor, such changes may interfere with psychoneuroimmunological regulatory networks and thus be of clinical relevance.
Genetic associations of leukoaraiosis indicate pathophysiological mechanisms in white matter lesions etiology
Authors: Lin Qing , Huang Wen-Qing , Tzeng Chi-Meng 
Published: March 2015

AbstractLeukoaraiosis (LA), also called white matter lesions (WMLs) and white matter hyperintensities (WMHs), is a frequent neuroimaging finding commonly seen on magnetic resonance imaging brain scans of elderly people with prevalence ranging from 50% to 100%. Although it remains asymptomatic, LA is not considered to be benign, and it is showed to be related to a host of poor clinical outcomes and increases the risk of disability, dementia, depression, stroke, and the overall morbidity and mortality. Pathologically, LA is characterized by loss of myelin and axons, patchy demyelination, and denudation of ependyma in regions of WMH. Age and hypertension are the most importantly established risk factors for LA. However, the precise pathogenic mechanisms remain unclear. Together with the previous findings, our recent genetic results strongly supported that LA is associated with immune response and neuroinflammation. Therefore, we confidently hypothesized that LA was not only a common neuroimaging phenomenon in the elderly but also an emerging neuroinflammatory disorder in the central nervous system. This article focusing on neuroimaging classification, genetics basis, and putative molecular mechanism introduced the basic knowledge and current status of LA and put forward some of our research ideas and results from our molecular genetics research, which may pave the way for deciphering the putative pathogenic mechanism, risk factor, epigenetic index, and its application in diagnostic agents or drug target for prevention and treatment. Thus, it could provide clinicians and researchers with a specific and modern overview of LA to enable the understanding of recent progress and future directions in this illness.