bluuebunny/crossref_metadata_2025_split huggingface dataset:
Propaganda Music in Second World War Britain: John Ireland's Epic March
Authors: Guthrie Kate 
Published: April 2014

ABSTRACTWhile biographical studies of British composers' experiences in the Second World War abound, little attention has been paid to how the demands of ‘total’ war impacted on music's ideological status. This article sheds new light on how composers and critics negotiated the problematic relationship between art music and politics in this period. John Ireland's Epic March – a BBC commission that caused the composer considerable anxiety – provides a case study. Drawing first on the correspondence charting the lengthy genesis of the work, and then on the work's critical reception, I consider how Ireland and his audiences sought to reconcile the conflicting political and aesthetic demands of this commission. With its conventional musical style, Epic March offers an example of a ‘middlebrow’ attempt to bridge the gap between art and politics.
Multiscale DNA partitioning: statistical evidence for segments
Authors: Futschik Andreas , Hotz Thomas , Munk Axel , Sieling Hannes 
Published: April 2014

Motivation: DNA segmentation, i.e. the partitioning of DNA in compositionally homogeneous segments, is a basic task in bioinformatics. Different algorithms have been proposed for various partitioning criteria such as Guanine/Cytosine (GC) content, local ancestry in population genetics or copy number variation. A critical component of any such method is the choice of an appropriate number of segments. Some methods use model selection criteria and do not provide a suitable error control. Other methods that are based on simulating a statistic under a null model provide suitable error control only if the correct null model is chosen.
Results: Here, we focus on partitioning with respect to GC content and propose a new approach that provides statistical error control: as in statistical hypothesis testing, it guarantees with a user-specified probability that the number of identified segments does not exceed the number of actually present segments. The method is based on a statistical multiscale criterion, rendering this as a segmentation method that searches segments of any length (on all scales) simultaneously. It is also accurate in localizing segments: under benchmark scenarios, our approach leads to a segmentation that is more accurate than the approaches discussed in the comparative review of Elhaik et al. In our real data examples, we find segments that often correspond well to features taken from standard University of California at Santa Cruz (UCSC) genome annotation tracks.
Availability and implementation: Our method is implemented in function smuceR of the R-package stepR available at http://www.stochastik.math.uni-goettingen.de/smuce.
Contact: andreas.futschik@jku.at or thomas.hotz@tu-ilmenau.de
Supplementary information: Supplementary Data are available at Bioinformatics online.
aLFQ: an R-package for estimating absolute protein quantities from label-free LC-MS/MS proteomics data
Authors: Rosenberger George , Ludwig Christina , Röst Hannes L. , Aebersold Ruedi , Malmström Lars 
Published: April 2014

Motivation: The determination of absolute quantities of proteins in biological samples is necessary for multiple types of scientific inquiry. While relative quantification has been commonly used in proteomics, few proteomic datasets measuring absolute protein quantities have been reported to date. Various technologies have been applied using different types of input data, e.g. ion intensities or spectral counts, as well as different absolute normalization strategies. To date, a user-friendly and transparent software supporting large-scale absolute protein quantification has been lacking.
Results: We present a bioinformatics tool, termed aLFQ, which supports the commonly used absolute label-free protein abundance estimation methods (TopN, iBAQ, APEX, NSAF and SCAMPI) for LC-MS/MS proteomics data, together with validation algorithms enabling automated data analysis and error estimation.
Availability and implementation: aLFQ is written in R and freely available under the GPLv3 from CRAN (http://www.cran.r-project.org). Instructions and example data are provided in the R-package. The raw data can be obtained from the PeptideAtlas raw data repository (PASS00321).
Contact: lars.malmstroem@imsb.biol.ethz.ch
Supplementary information: Supplementary Data are available at Bioinformatics online.
MRMPROBS suite for metabolomics using large-scale MRM assays
Authors: Tsugawa Hiroshi , Kanazawa Mitsuhiro , Ogiwara Atsushi , Arita Masanori 
Published: April 2014

Summary: We developed new software environment for the metabolome analysis of large-scale multiple reaction monitoring (MRM) assays. It supports the data format of four major mass spectrometer vendors and mzML common data format. This program provides a process pipeline from the raw-format import to high-dimensional statistical analyses. The novel aspect is graphical user interface-based visualization to perform peak quantification, to interpolate missing values and to normalize peaks interactively based on quality control samples. Together with the software platform, the MRM standard library of 301 metabolites with 775 transitions is also available, which contributes to the reliable peak identification by using retention time and ion abundances.
Availability and implementation: MRMPROBS is available for Windows OS under the creative-commons by-attribution license at http://prime.psc.riken.jp.
Contact: hiroshi.tsugawa@riken.jp
Supplementary information: Supplementary Data are available at Bioinformatics online.
Prognostic Significance of Nodal Ratio in Patients Undergoing Adjuvant Chemoradiotherapy After Curative Resection for Ampullary Cancer
Authors: Kim Kyubo , Chie Eui Kyu , Jang Jin-Young , Kim Sun Whe , Han Sae-Won , Oh Do-Youn , Im Seock-Ah , Kim Tae-You , Bang Yung-Jue , Ha Sung W. 
Published: April 2014

Objectives:
To analyze the outcome of patients with ampullary cancer who had undergone curative surgery followed by adjuvant chemoradiotherapy and to identify the prognostic factors for these patients

Methods:
Between January 1991 and August 2006, 71 patients with ampullary cancer underwent curative resection followed by adjuvant radiotherapy. There were 38 males and 33 females, and median age was 56 years (range, 28 to 77 y). Postoperative radiotherapy was delivered to tumor bed and regional lymph nodes up to 40 to 50 Gy at 2 Gy/fraction; 67 patients also received intravenous 5-fluorouracil as a radiosensitizer. Median follow-up duration was 72 months for survivors.

Results:
There were 5 isolated locoregional recurrences, 20 isolated distant metastases, and 11 combined locoregional and distant relapses. The 5-year locoregional relapse-free and overall survival rates were 76.2% and 64.5%, respectively. On multivariate analysis, nodal ratio and histologic differentiation were significant prognostic factors for overall survival (P=0.0382 and 0.0331, respectively).

Conclusions:
Adjuvant chemoradiotherapy after curative resection can achieve a long-term survival rate in patients with ampullary cancer. Nodal ratio and histologic differentiation are independent prognostic factors for these patients.
Comparison of Strength, Consistency, and Speed of COR-KNOT versus Manually Hand-Tied Knots in an Ex Vivo Minimally Invasive Model
Authors: Lee Candice Y. , Sauer Jude S. , Gorea Heather R. , Martellaro Angelo J. , Knight Peter A. 
Published: April 2014

Objective This study compared the strength, consistency, and speed of prosthetic attachment sutures secured with automated fasteners with those of manual knots using an ex vivo porcine mitral valve annuloplasty model. A novel miniature pressure transducer system was developed to quantify pressures between sutured prosthetic rings and underlying cardiac tissue. Methods Sixteen mitral annuloplasty rings were sewn into ex vivo pig hearts. Eight rings were secured with the COR-KNOT device; and eight rings, with hand-tied knots using a knot pusher. A cardiac surgeon and a surgery resident each completed four manually tied rings and four COR-KNOT rings via a thoracotomy trainer. The total time to knot and cut each ring's sutures was recorded. Suture attachment pressures were measured within (intrasuture) and between (extrasuture) each suture loop using a 0.5 × 2.0-mm microtransducer probe system. Results The suture holding pressures for the COR-KNOT fasteners were significantly greater than for the manually tied knots (median, 1008.9 vs 415.8 mm Hg, P < 0.001). All automated fasteners measured greater than 500 mm Hg, whereas 56% of the hand-tied knots were less than 500 mm Hg, and 14% were less than 75 mm Hg. There was less variation in attachment pressures for the COR-KNOT fasteners than for the hand-tied knots (SD, 401.6 vs 499.3 mm Hg, P = 0.04). Significant time savings occurred with the use of the COR-KNOT compared with manual tying (12.4 vs 71.1 seconds perknot, P = 0.001). Conclusions The novel microtransducer technology provided an innovative means of evaluating cardiac prosthetic anchoring sutures. In this model, mitral annuloplasty ring sutures secured with the COR-KNOT device were stronger, more consistent, and faster than with manually tied knots.
Critical success factors for implementation of risk assessment and management practices within the Tanzanian construction industry
Authors: Chileshe Nicholas , John Kikwasi Geraldine 
Published: April 2014

Purpose
– Despite the extensive research on critical success factors (CSFs), there is a paucity of studies that examine CSFs for the deployment of risk assessment and management processes in developing countries, particularly, Africa. The purpose of this paper is to investigate the perception of construction professionals on CSFs appertaining to the deployment of risk assessment and management practices (RAMP) in Tanzania with the aim of filling the knowledge gap.

Design/methodology/approach
– The primary data were collected from 67 construction professionals working with clients (private and public), consultants, and contractor organisations (foreign and local) within the Tanzanian construction. Response data was subjected to descriptive and inferential statistics with one-way analysis of variance to examine the differences in the perception of the identified CSFs.

Findings
– The descriptive and empirical analysis demonstrated a disparity of the ranking of the ten CSFs among the groups; however, the differences were not significant. Based on the overall sample, the results of the mean score ranking indicate that “awareness of risk management processes”; “team work and communications”; and “management style” were the three highly ranked CSFs whereas “co-operative culture”; “customer requirement”; and “positive human dynamics” were considered to be the least important.

Research limitations/implications
– The study did not differentiate the perceptions of the CSFs according to the ownership (local or foreign), and the sample consisted of organisations in one industry operating in Tanzania. Consequently, the findings may not generalise to other industries or to organisations operating in other countries.

Practical implications
– For RAMP to be implemented effectively, Tanzanian constructional-related organisations should consider the identified CSFs as a vehicle for improving project success through reduction of risk uncertainty. Furthermore, regardless of the type of organisation, “management style”, “team work and communication” are necessary for the successful deployment of RAMP.

Originality/value
– This study makes a contribution to the body of knowledge on the subject within a previously unexplored context. The study provides insights on the drivers and enablers (CSFs) of risk assessment implementation across the Tanzania construction sector.
The effect of construction demand on contract auctions: an experiment
Authors: Soo Alexander , Lan Oo Bee 
Published: April 2014

Purpose– The purpose of this paper is to present an experiment to test the effect of construction demand on the mark-up price level in construction contract auctions.Design/methodology/approach– An experimental approach was adopted for this study. In a controlled laboratory environment, a first-price sealed bid auction was simulated with varying number of projects available over ten rounds to simulate changing construction demand. Two experimental treatments were run in parallel, one exhibiting a “booming” demand over time, and the other group with a “recession” scenario. The experiment involved student (inexperienced) bidders with a construction project management background.Findings– The results show that inexperienced bidders do behave differently when subjected to varying levels of construction demand. Variations in the bid price level are affected by varying levels of construction demand and the general mark-up level for the bidders experiencing a booming scenario was higher on average compared to bidders subjected to the recession scenario.Research limitations/implications– An identified limitation of this study is the use of student subjects in the experiment, thus the experiment results are limited in generalisation to inexperienced bidders. Further studies may be able to replicate the experiment with experienced industry practitioners to observe the results.Practical implications– The results allow for industry practitioners to gain a stronger understanding of the effects of varying levels of construction demand and the need to consider construction demand in construction contracting. For construction clients, the level of construction demand may be used as an indicator to assist in the timing to call tenders to achieve a desirable price. For contractors, increased awareness of how demand affects competition and the price level will allow additional optimisations to be achieved in the bid price.Originality/value– Construction demand has been widely known to be one of the key factors affecting contractors’ bidding decisions. However, there has been little empirical investigation of the changes in bidders’ behaviour due to varying levels of construction demand. This paper attempts to add to the empirical research knowledgebase through an experimental setting.
Sexual differences in Lobelia spicata populations: floral morphometrics, stigma pollen loads, and pollen tube growth
Authors: Molano‐Flores Brenda , Faivre Amy E. 
Published: April 2014

AbstractIn many gynodioecious species, gender differences have been documented. Previous studies on populations of Lobelia spicata consistently documented hermaphrodites having larger corollas than females, but inconsistencies as to whether females had higher fruit set or not. In this study we expanded the data set on floral morphology, and to relate morphological differences to potential reproductive output we recorded stigma pollen loads and pollen tube growth to the ovary for both genders from four populations. Also, individuals were bagged to determine if and how much self‐pollen deposition occurred on stigmas. Because this species is self‐compatible but protandrous, it was thought unlikely to be able to self‐fertilize through autogamy. Hermaphroditic flowers were larger than female flowers in four out of the six flower traits analyzed. Overall, hermaphroditic flowers had larger corollas and stigma–nectary distance, but female flowers had longer and wider stigmas and more ovules. Open‐pollinated hermaphroditic flowers received more pollen grains on the stigma than female flowers. Positive correlations were found between floral morphological traits and stigma pollen load, but only for hermaphrodites. Pollen was found on the stigmas of all hermaphroditic bagged individuals and on a few female bagged individuals, though pollen tube growth was quite limited. Lastly, population differences were found. This study has identified several floral morphological traits and pollen grain/tube differences between genders and among populations for Lobelia spicata, supporting overall patterns identified in other gynodioecious species and adding a more detailed description of differences between the reproductive biology of each gender for this particular species.
Whose illness is it anyway? On facing illness as a couple
Authors: Altschuler Jenny 
Published: April 2014

This article explores current trends in research and clinical practice regarding life‐limiting illness and couple relationships; focusing on intimacy, gender, coping strategies and congruence in perceptions. A case example is used to illustrate how systemic ideas and techniques can help couples address the challenges they face and rethink what they want and need from each other.Practitioner points
In all clinical work it is important to bear witness to partners' shared and different experiences. It is also important to reflect on resonances with one's own experiences of loss and illness. Where couples are struggling, systemic techniques offer a way of increasing relational awareness, authenticity and mutuality.
Solubility of Fructose in Water–Ethanol and Water–Methanol Mixtures by Using H‐Bonding Models
Authors: Alavi Tahereh , Pazuki Gholamreza , Raisi Ahmadreza 
Published: April 2014

AbstractThe solubility of fructose in water–ethanol and water–methanol mixtures and the saturated density of each solution at 20, 30, and 40 °C over a range of water mass percentage have been measured. Also, a new modification of the Wilson model has been proposed to describe solubility data satisfactorily. The H‐UNIQUAC and H‐NRTL models were applied and a comparison between these 3 models was carried out. These 3 models were used to estimate the experimental data which was reported in this study. The comparison of the results showed that the H‐Wilson model has the lowest AAD% between these 3 models in correlating the solubility data and the saturated density.
Application of Oxidized Starch in Bake‐Only Chicken Nuggets
Authors: Purcell Sarah , Wang Ya‐Jane , Seo Han‐Seok 
Published: April 2014

AbstractThere is a need to reduce the fat content in fried foods because of increasing health concerns from consumers. Oxidized starches have been utilized in many coating applications for their adhesion ability. However, it is not known if they perform similarly in bake‐only products. This study investigated the application of oxidized starch in bake‐only chicken nuggets. Oxidized starches were prepared from 7 starches and analyzed for gelatinization and pasting properties. Chicken nuggets were prepared using batter containing wheat flour, oxidized starch, salt, and leavening agents prior to steaming, oven baking, freezing, and final oven baking for sensory evaluation. All nuggets were analyzed for hardness by a textural analyzer, crispness by an acoustic sound, and sensory characteristics by a trained panel. The oxidation level used in the study did not alter the gelatinization temperature of most starches, but increased the peak pasting viscosity of both types of corn and rice starches and decreased that of tapioca and potato starches. There were slight differences in peak force and acoustic reading between some treatments; however, the differences were not consistent with starch type or amylose content. There was no difference among the treatments as well as between the control with wheat flour and the treatments partially replaced with oxidized starches in all sensory attributes of bake‐only nuggets evaluated by the trained panel.Practical ApplicationThere is a need to reduce the fat content in fried food, such as chicken nuggets, because of increasing childhood obesity. Oxidized starches are widely used in coating applications for their adhesion ability. This study investigated the source of oxidized starches in steam‐baked coated nuggets for their textural and sensorial properties. The findings from this research will provide an understanding of the contributions of starch source and oxidation to the texture and sensory attributes of bake‐only nuggets, and future directions to improve the batter formulation for bake‐only nuggets.
Characterization of White Mahlab (Prunus mahaleb L.) Seed Oil: A Rich Source of α‐Eleostearic Acid
Authors: Sbihi Hassen Mohamed , Nehdi Imededdine Arbi , Al‐Resayes Saud Ibrahim 
Published: April 2014

AbstractSeed oils with high polyunsaturated fatty acid content are used in various industries including the food and pharmaceutical industries. White mahlab (Prunus mahaleb L.) seed was found to contain 31% oil. The oil was highly polyunsaturated and abundant in α‐eleostearic (38.32%), oleic (31.29%), and linoleic (22.96%) acids, which together comprised 93.91% of the total fatty acids. The α‐eleostearic acid was identified and characterized based on 1H‐NMR, UV, and FTIR spectroscopy. The oil was characterized by a relatively high quantity of tocopherols with γ‐tocopherol as the major tocopherol isomer. The physicochemical characteristics of the white mahlab seed and seed oil were also determined. The thermogravimetric analysis indicated that the oil was thermally stable up to 350 °C and began to decompose at 520 °C. This study demonstrated that these seeds may be reused and their oil incorporated into other food products, a beneficial practice considering that the compounds present in the seeds and oils have positive effects on human health.Practical ApplicationIn this study, mahlab seed oil was found to have potentials to become a new edible oil source as it contained a high level of polyunsaturated fatty acids especially, α‐eleostearic acid, which is a conjugated fatty acid rarely found in vegetable oils and has a beneficial effects on human health.
Predictive Modeling for Growth of Non‐ and Cold‐adapted Listeria monocytogenes on Fresh‐cut Cantaloupe at Different Storage Temperatures
Authors: Hong Yoon‐Ki , Yoon Won Byong , Huang Lihan , Yuk Hyun‐Gyun 
Published: April 2014

AbstractThe aim of this study was to determine the growth kinetics of Listeria monocytogenes, with and without cold‐adaption, on fresh‐cut cantaloupe under different storage temperatures. Fresh‐cut samples, spot inoculated with a 4‐strain cocktail of L. monocytogenes (∼3.2 log CFU/g), were exposed to constant storage temperatures held at 10, 15, 20, 25, or 30 °C. All growth curves of L. monocytogenes were fitted to the Baranyi, modified Gompertz, and Huang models. Regardless of conditions under which cells grew, the time needed to reach 5 log CFU/g decreased with the elevated storage temperature. Experimental results showed that there were no significant differences (P > 0.05) in the maximum growth rate k (log CFU/g h−1) and lag phase duration λ (h) between the cultures of L. monocytogenes with or without previous cold‐adaption treatments. No distinct difference was observed in the growth pattern among 3 primary models at various storage temperatures. The growth curves of secondary modeling were fitted on an Arrhenius‐type model for describing the relationship between k and temperature of the L. monocytogenes on fresh‐cut cantaloupe from 10 to 30 °C. The root mean square error values of secondary models for non‐ and cold‐adapted cells were 0.018, 0.021, and 0.024, and 0.039, 0.026, and 0.017 at the modified Gompertz, Baranyi, and Huang model, respectively, indicating that these 3 models presented the good statistical fit. This study may provide valuable information to predict the growth of L. monocytogenes on fresh‐cut cantaloupes at different storage conditions.