bluuebunny/crossref_metadata_2025_split huggingface dataset:
Correlation between angiographic transit times and neurological status on admission in patients with aneurysmal subarachnoid hemorrhage
Authors: Ivanov Alexander , Linninger Andreas , Hsu Chih-Yang , Amin-Hanjani Sepideh , Aletich Victor A. , Charbel Fady T. , Alaraj Ali 
Published: October 2015

OBJECT
The use of digital subtraction angiography (DSA) for semiquantitative cerebral blood flow(CBF) assessment is a new technique. The aim of this study was to determine whether patients with aneurysmal subarachnoid hemorrhage (aSAH) with higher Hunt and Hess grades also had higher angiographic contrast transit times (TTs) than patients with lower grades.

METHODS
A cohort of 30 patients with aSAH and 10 patients without aSAH was included. Relevant clinical information was collected. A method to measure DSA TTs by color-coding reconstructions from DSA contrast-intensity images was applied. Regions of interest (ROIs) were chosen over major cerebral vessels. The estimated TTs included time-to-peak from 0% to 100% (TTP0–100), TTP from 25% to 100% (TTP25–100), and TT from 100% to 10% (TT100–10) contrast intensities. Statistical analysis was used to compare TTs between Group A (Hunt and Hess Grade I-II), Group B (Hunt and Hess Grade III-IV), and the control group. The correlation coefficient was calculated between different ROIs in aSAH groups.

RESULTS
There was no difference in demographic factors between Group A (n = 10), Group B (n = 20), and the control group (n = 10). There was a strong correlation in all TTs between ROIs in the middle cerebral artery (M1, M2) and anterior cerebral artery (A1, A2). There was a statistically significant difference between Groups A and B in all TT parameters for ROIs. TT100–10 values in the control group were significantly lower than the values in Group B.

CONCLUSIONS
The DSA TTs showed significant correlation with Hunt and Hess grades. TT delays appear to be independent of increased intracranial pressure and may be an indicator of decreased CBF in patients with a higher Hunt and Hess grade. This method may serve as an indirect technique to assess relative CBF in the angiography suite.
Use of neuropathic pain questionnaires in predicting persistent postoperative neuropathic pain following lumbar discectomy for radiculopathy
Authors: Shamji Mohammed F. , Shcharinsky Alina 
Published: October 2015

OBJECT
Failed-back surgery syndrome has been historically used to describe extremity neuropathic pain in lumbar disease despite structurally corrective spinal surgery. It is unclear whether specific preoperative pain characteristics can help determine which patients may be susceptible to such postoperative disabling symptoms.

METHODS
This prospective study analyzed surgical microdiscectomy patients treated for lumbar, degenerative, painful radiculopathy. Clinical parameters included general demographics, preoperative and postoperative clinical examination status, self-reported pain and disability scores, and neuropathic pain scores. The screening tests for neuropathic pain were the Douleur Neuropathique 4 and Leeds Assessment of Neuropathic Symptoms and Signs, with correlation tested for ordinal score and screen positivity. Multiple logistic regression analysis was used to define predictors of postoperative symptomatology.

RESULTS
Twelve percent of the 250 patients with radiculopathy who underwent microdiscectomy experienced persistent postoperative neuropathic pain (PPNP) with only modest, if any, relief of leg pain. The condition was highly associated with abnormal preoperative screen results for neuropathic pain, but not sex, smoking status, or preoperative pain severity (α = 0.05). Good correlation was seen between the 2 screening tests used in this study for both absolute ordinal score (Spearman ρ = 0.84; p < 0.001) and the threshold for terming the patient as having neuropathic pain features (Spearman ρ = 0.48; p < 0.001). Younger age at treatment also correlated with a higher likelihood of developing PPNP (p = 0.03).

CONCLUSIONS
This population exhibited a low overall frequency of PPNP. Higher neuropathic pain screening scores correlated strongly with likelihood of significant postoperative leg pain. Further work is required to develop more accurate prognostication tools for radiculopathy patients undergoing structural spinal surgery.
Standardizing ICU management of pediatric traumatic brain injury is associated with improved outcomes at discharge
Authors: O’Lynnger Thomas M. , Shannon Chevis N. , Le Truc M. , Greeno Amber , Chung Dai , Lamb Fred S. , Wellons John C. 
Published: October 2015

OBJECTThe goal of critical care in treating traumatic brain injury (TBI) is to reduce secondary brain injury by limiting cerebral ischemia and optimizing cerebral blood flow. The authors compared short-term outcomes as defined by discharge disposition and Glasgow Outcome Scale scores in children with TBI before and after the implementation of a protocol that standardized decision-making and interventions among neurosurgeons and pediatric intensivists.METHODSThe authors performed a retrospective pre- and postprotocol study of 128 pediatric patients with severe TBI, as defined by Glasgow Coma Scale (GCS) scores < 8, admitted to a tertiary care center pediatric critical care unit between April 1, 2008, and May 31, 2014. The preprotocol group included 99 patients, and the postprotocol group included 29 patients. The primary outcome of interest was discharge disposition before and after protocol implementation, which took place on April 1, 2013. Ordered logistic regression was used to assess outcomes while accounting for injury severity and clinical parameters. Favorable discharge disposition included discharge home. Unfavorable discharge disposition included discharge to an inpatient facility or death.RESULTSDemographics were similar between the treatment periods, as was injury severity as assessed by GCS score (mean 5.43 preprotocol, mean 5.28 postprotocol; p = 0.67). The ordered logistic regression model demonstrated an odds ratio of 4.0 of increasingly favorable outcome in the postprotocol cohort (p = 0.007). Prior to protocol implementation, 63 patients (64%) had unfavorable discharge disposition and 36 patients (36%) had favorable discharge disposition. After protocol implementation, 9 patients (31%) had unfavorable disposition, while 20 patients (69%) had favorable disposition (p = 0.002). In the preprotocol group, 31 patients (31%) died while 6 patients (21%) died after protocol implementation (p = 0.04).CONCLUSIONSDischarge disposition and mortality rates in pediatric patients with severe TBI improved after implementation of a standardized protocol among caregivers based on best-practice guidelines.
Verbal Reduplication and Grammaticalization: A Study of Mandarin VV-kan and V-kankan Constructions
Authors: Cheng Yi-Yang 
Published: October 2015

<p>The present study investigates two constructions in Mandarin — <em>VV-kan</em> and<em> V-kankan</em>— which show an interesting formal asymmetry in the distribution of verbal reduplication and <em>kan</em> ‘see’, but denote the same meaning ‘try … and find out’.</p>
Le « miroir » de la comparaison internationale. Politiques et mises en scène des chiffres sur l’éducation dans la « société de la connaissance »
Authors: Tréhin-Lalanne Rémi 
Published: October 2015

Cet article étudie le rôle des chiffres dans la « nouvelle gouvernance » européenne à travers l’analyse ethnographique d’une conférence internationale sur la comparaison des systèmes éducatifs. Le modèle de comparaison promu lors de cette rencontre est marqué par le recours exclusif aux outils de quantification, élaborés conjointement par des bureaux d’études, des administrations nationales et des institutions supranationales, principalement l’UNESCO, l’OCDE et la commission Européenne. Le recours aux chiffres et leur force d’imposition sont ainsi étudiés dans leur triple dimension : technique, normative et symbolique.
La politisation par l’intime
Authors: Muxel Anne 
Published: October 2015

Les modalités des discussions politiques, de leurs contenus, et de leurs arbitrages, dans les relations interpersonnelles sont peu connues dans la sociologie électorale française. Qui parle de politique et avec qui ? Quels sont les sujets qui fâchent ? Dit-on pour qui l’on vote ? Cette étude de la parole politique dans l’espace privé de la vie de famille, du couple, et de l’amitié, éclaire certains mécanismes de politisation des individus dans et par l’intime, ainsi que des phénomènes révélateurs de la dimension affective de toute existence politique. Elle s’appuie sur un matériau empirique élaboré à partir d’enquêtes quantitatives menées auprès d’échantillons représentatifs de la population française, et notamment sur une enquête inédite conduite au Cevipof dédiée à l’exploration des liens entre politique, affectivité et intimité.
Vers un modèle de democratié chrétienne ?
Authors: Invernizzi Accetti Carlo 
Published: October 2015

Cet article vise à montrer l’utilité heuristique d’un idéal-type de « démocratie chrétienne » pour comprendre comment sont structurés les rapports entre politique et religion au sein du traité qui fonde et régit actuellement le fonctionnement de l’Union européenne. La première partie est consacrée à une reconstruction de cet idéal-type de « démocratie chrétienne », mettant en relief sa spécificité par rapport aux notions de « laïcité » et de « sécularisme ». La deuxième partie offre ensuite une relecture du traité de Lisbonne à la lumière de ces trois notions, soulignant les éléments qui concordent avec la première et qui remettent donc en cause le fait que l’Union européenne puisse être adéquatement décrite comme « laïque » ou « séculière ».
Plasma miR-185 as a predictive biomarker for prognosis of malignant glioma
Authors: Tang Hailin , Liu Qing , Liu Xiaoping , Ye Feng , Xie Xinhua , Xie Xiaoming , Wu Minghua 
Published: October 2015

Introduction:
Specific microRNA (miRNA) expression signatures have been identified in a variety of human cancers. More recently, increasing evidence shows that miRNAs exist in human blood serum and plasma.

Materials and Methods:
Levels of miR-185 in plasma were measured by quantitative reverse-transcriptase polymerase chain reaction in 66 glioma patients, 11 pituitary adenoma patients, 32 meningioma patients, and 14 acoustic neuroma patients.

Results:
The plasma levels of miR-185 were significantly altered in glioma patients compared to normal controls. However, its levels were not observably changed in patients with other brain tumors such as meningioma, acoustic neuroma, or pituitary adenoma. Furthermore, the plasma levels of miR-185 in glioblastoma multiforme patients with operation and chemo-radiation almost revived to normal levels. Finally, we also demonstrated that low plasma miR-185 levels are correlated with poor survival in glioma patients.

Conclusion:
These findings suggest that plasma miR-185 has become potential biomarkers for glioma and may be useful in clinical management for glioma patients.
Intensity modulated radiation therapy (IMRT) is not superior to three-dimensional conformal radiation (3DCRT) for adjuvant gastric radiation
Authors: Chopra Supriya , Agarwal Aditi , Engineer Reena , Dora Tapas , Thomas Biji , Sonawone Supriya , Paul Siji N. , Kannan Sadhna , Patil Prachi , Mehta Shaesta , Shrivastava Shyam Kishore 
Published: October 2015

Aims:
To compare three-dimensional conformal radiation (3DCRT) and Intensity Modulated Radiation Therapy (IG-IMRT) for adjuvant gastric irradiation.

Subjects and Methods:
From Jan 2010-Aug 2013, all patients undergoing 3DCRT and IG-IMRT were included. Systemic chemotherapy included 1 cycle before and 2 cycles after chemoradiation. Planning Target Volume (PTV) received 45 Gy/25 fractions/5 weeks with concurrent capcetabine 825 mg/m2 bid. Matched pair analysis was performed to evaluate imbalance in two cohorts if any. Common Toxicity Criteria for Adverse Event (CTCAE) vs 3.0 was used to record gastrointestinal (GI), hematological (HL), and renal toxicity during treatment and follow-up. Patterns of recurrence were documented. Mann-Whitney U test was used for statistical comparison.

Results:
Of the 51 patients, 26 received 3DCRT and 25 IMRT. IMRT led to decrease in dose received by right and left kidney (12.4 Gy and 7.1 Gy and 29 Gy vs 8.2 Gy; P < 0.001). Overall, 17.6% and 19.6% patients had grade II GI and HL toxicity and 3.9% and 5.9% had grade III GI and HL toxicity. No difference was observed in acute grade II-V GI or HL toxicity (11.5% vs 24%, P = 0.07; 7.6% vs 20% P = 0.20) or late GI, HL, or renal toxicity between 3DCRT and IMRT. No difference was observed in patterns of local relapse (11.5% vs 12%, P = 0.14) or overall survival (39% and 38% (P = 0.97)) between 3DCRT and IMRT.

Conclusions:
3DCRT and IMRT are equivalent in terms of toxicity and local control.
Comparaison de deux scénarios (statistique et dynamique) concernant les précipitations hivernales en Grèce
Authors: Tolika Konstantia , Maheras Panagiotis , Vafiadis Margaritis , Anagnostopoulou Christina 
Published: October 2015

Le but de ce travail est l’évaluation de deux techniques de « désagrégation d’échelle » (statistique et dynamique) pour la simulation des précipitations hivernales en Grèce. La méthode statistique se base sur l’utilisation du principe des réseaux de neurones artificiels (RNA). Pour la construction du modèle statistique, sept prédicteurs sont utilisé. Les meilleurs résultats ont été obtenus par le prédicteur suivant : géopotentiels au niveau 500 hPa combiné avec l’humidité spécifique et les précipitations. Les données de la méthode dynamique proviennent d’un modèle climatique régional (RCM). La comparaison des résultats obtenus par les deux techniques (statistique et dynamique) a été faite en comparant les valeurs des pluies de chaque station simulées par la méthode statistique avec les valeurs moyennes (précipitations simulées par le modèle HadRM3P) de quatre points de grille entourant la station. D’après les résultats obtenus, les deux méthodes s’avèrent efficaces pour la simulation des précipitations hivernales en Grèce. Leurs totaux semblent être en réduction jusqu’à la fin du 21ème siècle (la réduction, selon les scénarios, varie entre 14 et 35%).
Prédétermination régionale des pluies d’occurrence fréquente à exceptionnelle : application au pourtour méditerranéen français
Authors: Fouchier C. , Lavabre J. , Gregoris Y. , Sol B. , Desouches C. , Faure-Soulet A. 
Published: October 2015

Un générateur stochastique de pluies horaires est mis en œuvre dans le cadre d’une méthode originale de prédétermination des débits de crue la méthode SHYPRE (Simulation d’HYdrogrammes pour la PREdétermination des crues). Ce générateur de pluies est paramétré par deux grandeurs caractéristiques de la pluie journalière facilement accessibles. Leur régionalisation sur le littoral méditerranéen français met en œuvre une régression multiple sur des caractéristiques du relief. La connaissance des quantiles de pluie de toutes durées (entre 1 heure et 72 heures heures ainsi que sur la journée) pour des périodes de retour comprises entre 2 et 1 000 ans est alors possible en tout point de la zone d’étude. Les performances du modèle sont évaluées sur sa capacité à reproduire les quantiles de pluie journalière aux postes de calage. Les résultats de la simulation sont ensuite confrontés aux estimations des pluies horaires et journalières rencontrées dans la littérature.
A Comparative Study of the Impact of Qualitative-Descriptive Evaluation and Quantitative Evaluation Methods on Academic Progress and Academic Motivation among Sixth Grade Students
Authors: Sahraee Akram , Mahdian Mohammad Jafar , Dinarvand Hasan 
Published: October 2015

<p>The aim of the present research has been to comparatively study the impact of qualitative-descriptive evaluation and quantitative evaluation methods on the academic progress and academic motivation among sixth grade students in Mahidasht region in educational year 2014. Statistical population of the study included all the sixth grade students of Mahidasht region. From among the population of the study, 151 students were selected through convenience sampling, out of which 33 persons were placed in qualitative-descriptive evaluation group and 118 persons were placed in quantitative group. Research methodology has been applied and causal-comparative in terms of purpose and nature respectively.Validity and reliability of the instruments were appropriate. Cronbach’s alpha coefficient was 0.78 for the researcher-made academic progress questionnaire. In order to analyze the data, independent t-test was used; and Mann–Whitney U test was also used for examining the accuracy of the findings. The results indicated that students’ academic progress in quantitative evaluation group (9.24) has been lower than in qualitative evaluation group (10.51). Besides, the results revealed that academic motivation of (all) students in quantitative evaluation group (111.84) has been lower than in qualitative evaluation group (120.27).it is suggested to consider the positive role of qualitative-descriptive evaluation method on academic progress and academic motivation of the elementary students. </p>
A New Player in Chronic Kidney Disease Mineral and Bone Disorder: Tenascin-C
Authors: Ozkan Gulsum , Ulusoy Sukru , Guvercin Beyhan , Menteşe Ahmet , Karahan Suleyman Caner , Yavuz Adnan 
Published: October 2015

Aims Chronic kidney disease-mineral and bone disorder (CKD-MBD) is a condition frequently observed in CKD. The search for a reliable and easy to use biomarker in the diagnosis of CKD-MBD is continuing. Tenascin-C (TN-C) is an important extracellular (ECM) protein synthesized by osteoblasts during bone growth and morphogenesis. The purpose of this study was to assess the relation between inflammation and MBD and TN-C in HD patients and to identify a new marker that can be used to help diagnose CKD-MBD. Materials and methods 136 HD patients and 22 healthy controls were enrolled in this cross-sectional, observational multicenter study. Once patients’ demographic and biochemical parameters had been recorded, peripheral blood samples were collected for TN-C measurement before the mid-week HD session. The relationship between TN-C levels and demographic and biochemical parameters was then assessed. Results TN-C levels were significantly higher in the HD patient than in the control group ( P<.001). Intact parathormone (iPTH) affected TN-C levels in the HD patient group. TN-C levels was significantly higher in both the high (>300 pg/ml) and low iPTH groups (<150 pg/ml) compared to the 150–300 pg/ml iPTH group ( P<.001, <.001 respectively). Conclusions This study showed, for the first time in the literature, high levels of TN-C in the low and high iPTH groups and that this elevation was associated with iPTH. We think that if our study is supported by further research, TN-C can be a biomarker capable of use in diagnosing CKD-MBD.
Clinical Significance of Mucinous Rectal Adenocarcinoma following Preoperative Chemoradiotherapy and Curative Surgery
Authors: Kim Tae Gyu , Park Won , Choi Doo Ho , Park Hee Chul , Kim Seok-Hyung , Cho Yong Beom , Yun Seong Hyeon , Kim Hee Cheol , Lee Woo Yong , Lee Jeeyun , Park Joon Oh , Park Young Suk , Lim Ho Yeong , Kang Won Ki , Chun Ho-Kyung 
Published: October 2015

Aims To investigate the efficacy and prognosis associated with preoperative chemoradiotherapy in patients with locally advanced mucinous rectal cancer (MRC). Methods Our analysis included 412 patients who underwent preoperative chemoradiotherapy and curative surgery for locally advanced rectal cancer. Among these patients, 30 had MRC and 382 had nonmucinous rectal cancer (NMRC). Tumor downstaging, defined as a lower pathologic stage than clinical stage, and survival were compared between MRC and NMRC. Results Increased frequency of cT4 disease was seen in MRC compared to NMRC (23.3% vs 8.9%, p = 0.021). Complete pathologic response rate and tumor downstaging rate were 0% and 23.3% in MRC and 15.4% and 52.4% in NMRC, respectively (p = 0.025 and p = 0.002). There was no significant difference in disease-free survival between the 2 groups (62.1% vs 75.0% at 5 years, p = 0.170), while there was a significantly lower overall survival in MRC vs NMRC (67.4% vs 88.0% at 5 years, respectively; p = 0.012). When analyzed by stage, the overall survival difference between MRC and NMRC was significant in the cT3 group (71.1% vs 89.1% at 5 years, p = 0.047) and marginally significant in the cT4 group (51.4% vs 74.5% at 5 years, p = 0.053), but not significant in subgroups with the same pathologic stage. Conclusions Mucinous rectal cancer is related to a lower response rate to chemoradiotherapy and poorer prognosis compared to NMRC, even when corrected for clinical stage. The poor prognosis in MRC might be associated with poor responsiveness to preoperative chemoradiotherapy.
La recherche traductologique dans les domaines de spécialité : un nouveau tournant
Authors: Vandaele Sylvie 
Published: October 2015

La recherche liée à la traduction pragmatique, et notamment dans les domaines de spécialité est, historiquement, minoritaire, car la traductologie occidentale s’est essentiellement développée à partir de questions soulevées par la traduction littéraire. Pourtant, la traduction pragmatique domine largement la pratique professionnelle. De même, la recherche traductologique a été l’objet de réticences de la part des praticiens et des étudiants. Nous formulons l’hypothèse que les préjugés négatifs, des deux côtés, trouvent leur source chez certains auteurs princeps fondateurs de la traductologie. La présente conférence explore ainsi les positions exprimées chez Berman, Schleiermacher et Ortega y Gasset, et remet en question la carte de Holmes, pour arriver à proposer une autre carte qui ouvre toutes les possibilités autant sur le plan de la recherche que sur le plan de la pratique. Par ailleurs, en raison du développement des outils informatiques, nous sommes convaincue que le traducteur devra de plus en plus se positionner comme un expert capable de conseiller adéquatement les donneurs d’ouvrages. Nous nous proposons donc, pour terminer, de dégager quelques pistes de recherche, concernant plus spécifiquement les domaines de spécialité, qui pourront s’épanouir dans le contexte de la traductologie, avec pour arrière-plan une volonté délibérée d’arrimer la pratique à la recherche et à la réflexion dite « théorique », et réciproquement.
Initial electrification to the first lightning flash in New Mexico thunderstorms
Authors: Stolzenburg Maribeth , Marshall Thomas C. , Krehbiel Paul R. 
Published: October 2015

AbstractThe initial electrification of three New Mexico thunderstorms is examined using in situ and remote measurements. The earliest deflection of electric field (E) measured at the surface was 5–8.6 min before the first flash and coincident with the development of substantial radar reflectivity (40 dBZ) above −5°C. Rapid growth of surface E (>5 V/m/s) started 2.4–3.1 min before the first flash, when 40 dBZ reflectivities reached above the −15°C level. In two cases with clear surface E records, radar reflectivity indicators (40 dBZ echo through −10°C and echo top through −15°C) would yield longer warning times before the first flash than the E record. The first flash in each storm initiated at altitudes between 7.4 and 8.8 km; hence, the temperatures where the largest (negative) E for normal intracloud lightning initiation had developed during the initial electrification were −10°C to −20°C. Negative and positive charge regions associated with the first flash in each cell were centered at −8°C to −16°C (6.9–8.0 km) and −20°C to −24°C (9.0–9.2 km), respectively. In two cases, balloon data indicate the only substantial charge regions present before the first flash were those involved in the flash. Another case shows an initial period of opposite polarity E deflection at the surface coincident with substantial low‐level positive charge within the cloud, although this charge was not involved in the first 8 min (first 17 flashes) of lightning activity. The findings support the notion that the initial electrification resulted from charging via the noninductive ice‐ice collisional mechanism.