bluuebunny/crossref_metadata_2025_split huggingface dataset:
Elevated Lipoprotein Lipase Activity Does Not Account for the Association Between Adiponectin and HDL in Type 1 Diabetes
Authors: Calderon Rossana M. , Diaz Sylvia , Szeto Angela , Llinas Jose A. , Hughes Thomas A. , Mendez Armando J. , Goldberg Ronald B. 
Published: May 2015

Context:
Increased high-density lipoprotein cholesterol (HDL-C) is common in type 1 diabetes (T1D) and is associated both with hyperadiponectinemia and with elevated lipoprotein lipase activity (LPL). Because adiponectin has been shown to increase LPL expression, elevated LPL may link the hyperadiponectinemia in T1D with increased HDL.

Objective:
The purpose of this study was to determine whether LPL activity accounts for the association between adiponectin and HDL in T1D.

Design, Participants, and Setting:
A cohort of 127 patients with T1D attending the Diabetes Clinic at the University of Miami and 103 healthy control subjects were recruited.

Main Outcome Measure:
HDL-C and adiponectin were measured in the full cohort and in a subgroup, HDL subfractions were obtained by ultracentrifugation, and LPL and hepatic lipase were measured in postheparin plasma.

Results:
Total HDL-C and the lowest density HDL subfraction, apolipoprotein A-I, LPL activity, and adiponectin levels were higher in subjects with T1D than in control subjects (P &lt; .05). Both adiponectin and LPL activity were directly associated with total HDL-C and its lowest density subfraction, but adiponectin and LPL were not correlated (P = 0.13). Adiponectin alone explained 11.6% and adiponectin plus LPL explained 23.8% of the HDL-C variance. In a multivariate model, adiponectin remained an independent predictor of HDL-C along with LPL and serum creatinine, explaining together 27% of HDL-C variance.

Conclusions:
Adiponectin was strongly associated with HDL-C in T1D, suggesting that hyperadiponectinemia is linked to the elevated HDL-C in this population. However, this relationship is independent of the association between LPL and HDL-C. Thus, elevated adiponectin and LPL activity are independently related to increased HDL-C in T1D.
Minireview: Role of Intracellular Scaffolding Proteins in the Regulation of Endocrine G Protein-Coupled Receptor Signaling
Authors: Walther Cornelia , Ferguson Stephen S. G. 
Published: May 2015

AbstractThe majority of hormones stimulates and mediates their signal transduction via G protein-coupled receptors (GPCRs). The signal is transmitted into the cell due to the association of the GPCRs with heterotrimeric G proteins, which in turn activates an extensive array of signaling pathways to regulate cell physiology. However, GPCRs also function as scaffolds for the recruitment of a variety of cytoplasmic protein-interacting proteins that bind to both the intracellular face and protein interaction motifs encoded by GPCRs. The structural scaffolding of these proteins allows GPCRs to recruit large functional complexes that serve to modulate both G protein-dependent and -independent cellular signaling pathways and modulate GPCR intracellular trafficking. This review focuses on GPCR interacting PSD95-disc large-zona occludens domain containing scaffolds in the regulation of endocrine receptor signaling as well as their potential role as therapeutic targets for the treatment of endocrinopathies.
Puzzle—Chess Avoidance Puzzles
Authors: Chlond Martin J. 
Published: May 2015

Atype of chess based puzzle devised by Erich Friedman is described and modeled using integer programming. In these puzzles the solver is required to place a given set of chess pieces on to an irregular grid such that no occupied squares are attacked by another piece. A MathProg model is included together with an Excel spreadsheet with the model embedded The purpose of this is to encourage instructors to investigate the possibility of using the Excel add-in SolverStudio as a teaching tool.
Forest Products Industry in a Digital Age: A Look at E-Commerce and Social Media
Authors: Montague Iris , Gazal Kathryn Arano , Wiedenbeck Jan , Shepherd Jean-Gabriel 
Published: May 2015

Abstract
The business of marketing, promotions in particular, has changed substantially during the past decade. Physical means of promotion (e.g., newspapers, magazines, radio, billboards) have seen a decline, and the use of social media as a marketing tool has increased significantly. While a number of studies regarding the use of social media among Fortune 500 companies have been conducted, very limited information is available regarding social media use in the US forest products industry. This article presents part one of a two-part series and addresses the first three of the following five objectives: (1) identify the type(s) of e-commerce and social media tools forest products companies use, (2) identify and describe the reasons a company chooses to use or not use social media as a marketing tool, (3) identify and describe perceptions held about social media as a marketing tool, (4) examine factors affecting the use of social media marketing in the forest products industry, and (5) examine the effectiveness of social media marketing. The study included a questionnaire that was mailed to US forest products manufacturers in late 2013. Results show that close to 58 percent of respondents currently use some form of social media. The most common social media tool implemented was Facebook. Increasing company exposure and branding were cited as the most important reasons for using social media. Security of sensitive information and the cost of implementing a social media marketing strategy were the top concerns about adopting social media. The information collected from this study can be used in assisting the forest products industry in understanding the social media marketing world and developing an effective social media marketing strategy.
Decline in the Pulp and Paper Industry: Effects on Backward-Linked Forest Industries and Local Economies
Authors: Brandeis Consuelo , Guo Zhimei 
Published: May 2015

Abstract
Pulp, paper, and paperboard mills consume close to 52 percent of southern roundwood, providing a significant market to southern forest landowners. Declining numbers of pulpwood-using mills and downward trends in mill capacity, however, present a growing challenge to the southern forest sector. Shrinking mill capacity affects rural communities that depend on mill demand for labor and other production inputs. This study investigates the effect of pulp mill closures on the regional and local economy, focusing on the spillover effects to forestry and forest products industry. Multiregional input–output models were built for two mill closures using Impact Analysis for Planning (IMPLAN) showing linkages among different sectors, households, and governments in the regional economy. Results revealed the different effects across wood procuring zones with areas displaying significant loss in logging activity. Significance to other forestry-related industries depended on closed mills' inputs. We compared our results with information available in the literature regarding expected economic impact from a wood pellet mill, an alternative market for small-size wood. We expect research results will provide valuable information to policymakers and managers when addressing likely future changes in the paper manufacturing industry.
Histomorphometric analysis of the effects of calcitonin on alveolar socket repair in diabetic rats
Authors: Delgado Adriana da Mota , Fernandes Gomes Mônica , De Oliveira Amorim José Benedito , Mariuba Marta Verônica 
Published: May 2015

O objetivo desse estudofoi fazer uma avaliação histomorfométrica da cicatrização do alvéolo dental na presença crónica de calcitonina de salmão (16UI/Kg) na condição do diabetes. Para isso sessenta ratos albinos foram utilizados. Estes animais foram divididos em três grupos: controle (C), diabético (D) e diabéticos tratados com calcitonina(Dca). Os grupos D e Dca receberam uma injeção única 45mg/Kg intraperitoneal de estreptozotocina-STZ. Após duas semanas, todos os animais foram submetidos a exodontia do incisivo superior direito e cinco animais de cada grupo foram sacrificados aos 15, 30 e 45 dias pós-operatórios. As peças foram fixadas, descalcificados e incluídas em parafina. Os blocos obtidos foram cortados com 6 micrômetros de espessura e corados com hematoxilina e eosina para estudo morfológico. De acordo com os resultados obtidos verificou-se que nos animais tratados com calcitonina houve alteração na cicatrização da ferida após extração dental, atenuando o comprometimento da dinâmica da reparação óssea comumente observada no estado diabético.
Influence of dentin abrasion methods on the bond strength of self-etching adhesive systems
Authors: Rocha Patrícia Itocazo , Zanatta Rayssa Ferreira , Pagani Clóvis , Rodrigues José Roberto , Borges Alessandra Bühler 
Published: May 2015

The aim of this study was to compare the bond strength of two self-etching adhesive systems with different types of dentin abrasion. Thirty two sound human molars were selected and had the dentin surface exposed and flattened. Tooth were randomly divided into four experimental conditions, according with the adhesive system [Clearfil SE Bond (SE) and One- Up Bond F(ONE)] and the type of dentin abrasion [conventional diamond bur (D) and ultrasounddiamond bur (CVD)]. The adhesives were applied following manufactures’ instructions and light cured composite blocks of 4mm height were placed over dentin. After storage in distilled water for 24 h in 37 ºC, serial cuts were made on mesio-distal and buccal-lingual direction, obtaining specimens with stick format, with cross section of 8mm². The microtensile test was performed at a crosshead speed of 0.5 mm/min and load cell of 10kg, until failure. Data were submitted to ANOVA-2-Way followed by Tukey test (5%). The results (MPa) were: D/SE:24.06±8.84, D/ONE:15.03±8.61, CVD/SE:39.90±8.24 and CVD/ONE:15.03±8.61. It can be concluded that the adhesive system Clearfil SE Bond showed higher bond strengthrelated with the abrasion with CVD; the type of dentin abrasion interfered on the performance of Clearfil SE Bond but did not influence the One-Up Bond F results.KEYWORDSSelf-etching adhesive systems, Microtensile, Bondstrength, Dentin.
The use of bisphosphonates in dental clinic: a review of the last five years
Authors: Pereira Yamba Carla lara , Do Nascimento Glauce Crivelaro 
Published: May 2015

The bisphosphonates are drugs for synthetics used without treatment of neoplasms and bone, Paget's disease and more reason for excitement in cases of postmenopausal osteoporosis. These drugs resemble some known side effects, however, was recently identified a new complication, with oral manifestation, called Osteonecrosis. When this necrosis of the bone bases is associated to the use of Bisphosphonates, gets its name from Osteonecrosis of MS would expire by Bisphosphonates. The type of bisphosphonate, a route of administration and duration of treatment with these drugs seem to have direct relation with the incidence of osteonecrosis associated with bisphosphonates. The aim of this work was to present a revision last five in relation to available bisphosphonates groups Brazil, emphasizing those used in the treatment of Osteoporosis, associating them to Osteonecrosis of would expire and as possible prior to diagnostic aspects from image Diagnostics. It is the impact of these non-current world stimulated new lines of research looking for the larger of these illnesses, perishes opening its, Qin as best approaches and forms of diagnosis faster, aiming to improve circulation and reduce treatment possible unwanted side effects. Key Words: Biphosphonates, Osteonecrosis of the Jaws, Dental radiographs, Treatment.
May the flexural strength of ceramics be influenced by salivary pH?
Authors: Cotes Caroline , Macedo Vanessa Cruz , Camillo Mariana , Lara Bruna , Carvalho Rodrigo , Martinelli Carolina , Kimpara Estevao 
Published: May 2015

Objective. This study purpose was compare the three-point flexural strengths of 50 feldspathic ceramic after storage in artificial saliva. Material and methods. The bars were luted with resin cement and subjected to storage in artificial saliva of different pHs. Results. The values of flexural strength were significantly higher for the bars stored in distilled water, at neutral and basic pH, when compared with the results for the bars stored in acidic pH and in acid/basic pH. Conclusions. Storage for 30 days in artificial saliva at acidic pH, or alternating between acidic and basic pH, can reduce the mechanical properties of ceramics.
Histological and microhardness evaluation of early artificial carious lesions in human and bovine enamel: in vitro study
Authors: Masuda Allan Kenji , Quitero Mayra Fidelis Zamboni , Espejo-Trung Luciana Cardoso , Cerqueira Luz Maria Aparecida Alves 
Published: May 2015

Objective: Early carious lesions in bovine and humanenamel developed in vitro using a pH cycling regimenwere compared. Material and Methods: Fifteencentral bovine incisors and fifteen recently extractedhuman third molars were randomly divided into twogroups: ten for the cross-sectional microhardness test(MT) and five for polarized light microscopy (PLM)analysis. Enamel blocks measuring 5 x 5 mm weremade from the buccal face of the teeth. The blocksused for the MT were sliced into two halves: “A” and“B”. “A” slices were embedded in acrylic resin, withthe face of the dentin-enamel junction left exposedfor the MT prior to pH cycling. “B” slices and wholeblocks were coated with acid-resistant varnish,except a 3 x 3 mm central window, and submitted tothe pH cycling regimen (demineralizing solution for3 h and remineralizing solution for 21 h) over fiveconsecutive days. The “B” slices were then submittedto the MT and the whole blocks were processed forthe PLM study. Results: The PLM analysis revealedshallow, extensive lesions in the bovine enamel,hardly showing the superficial, dark and translucentzones, as well as deep cavity lesions in the humanenamel, with the body of the lesion and the darkzone evident. The MT revealed a significant decreasein microhardness in the superficial levels of thebovine enamel caries and at all depth levels of thehuman enamel caries. Conclusion: The pH cyclingregimen adopted led to the development of deeperand more demineralized carious lesions in humanenamel than bovine enamelKeywordsDental caries; Dental enamel; Microhardness tests; Polarization microscopy.
Influence of adhesive system in bond strength of fiber glass posts to radicular dentin using dual cure resin cement
Authors: Barcellos Daphne Camara , Huhtala Maria Filomena Rocha Lima , Silva Melissa Aline , Gomes Ana Paula Martins , Franco Lucas Teixeira 
Published: May 2015

The purpose of this study was to evaluate the bond strength between root dentin and glass fiber posts cemented with dual cure resinous cement associated with the conventional and self-etching adhesive systems. Twenty-four single-rooted human teeth were selected, and the crowns were removed at the cement enamel junction. The roots received biomechanical preparation and obturation followed by the intraradicular preparation compatible with a drill diameter of the glass fiber posts. The roots were divided into two groups, according to cementation protocol (n-12): Group 1 - etched with 37% phosphoric acid for 30 seconds, total-etch adhesive system Single Bond (3M ESPE) and Enforce resinous cement (Dentsply); Group 2 – self-etch adhesive system One Up Bond F (Tokuyama) and Enforce resinous cement (Dentsply). After the posts cementation, the roots were kept at 370 C for one week, and submitted to pull out test on the universal testing machine Emic to a traction speed of 1 mm/min. Data in MPa were submitted to the statistical t-test (5%). The t-test showed significant differences between the two groups (p=0.003). The average values in MPa (±standard-deviation) were: Group 1: 5.28(±3.25), Group 2: 10.05(±3.78). Enforce associated with the self-etch adhesive system One Up Bond F showed significantly higher bond strength values than Group 1 - Enforce associated with the total-etch adhesive system Single Bond.
Influence of sandblasting distance on enamel and ceramic structure bond strength
Authors: Garcia Lorena Rincon , Reyes Ana Cecilia Roso , Canal Maria Isabel , Castilho Mauricio Peña , Gomes Osnara Maria Mongruel , Dominguez John Alexis 
Published: May 2015

Objetive: The purpose of this study is was to evaluate the influence of sandblasting ceramic and enamel structure on bond strength, changing distance.Material and methods: 60 third molars , were selected, enamel surfaces were ground flat with wet 600 - 2000 grit aluminum oxide abrasive papers and polished with three, one, and one-fourth micrometer-grit diamond pastes. Obtained 120 lithium disilicate-based core ceramic discs ( 2 mm diameter;1 mm thickness), divided into 7 groups [Group C, don’t sandblasting, Group SB-E(5-10) enamel sandblasting 5 and 10 mm, Group SB-C(5-10) ceramic sandblasting 5 mm and 10 mm, Group SB-EC(5-10) enamel and ceramic sandblasting 5 mm and 10 mm] after was performed microshear and Atomic Force Microscopy (AFM), Statistic Teste of normality , after one-way ANOVA and Tukey test (?: 0.05).Results: The group C present bond strength (59.2±12.5), the group SB-E 5 mm (21.7±08.8) (p<0.005), the group SB-E10 (53.6±14.3).Conclusion: The use of sandblasting treatment of the enamel surface a 5 mm by 20 seconds decreases the bonding strength to microshear.
Imaging aspects of the dentigerous cyst magnetic in resonance imaging and ultrasound
Authors: Pinto Antonione Santos Bezerra , Araújo Thyago Leite Campos de , Dias Sávia Francisca Lopes , Guimarães Maria Adelaide , Pinto Moara e Silva Conceição , Lopes Sérgio Lúcio Pereira de Castro 
Published: May 2015

Magnetic resonance imaging (MRI) is a type of imaging study considered the gold standard in the analysis of the internal structure and content of intraosseous lesions, allowing for their inherent characteristics of acquisition, determine the nature and differential diagnosis between changes that have aspects Similar to other imaging modalities, such as on radiographs and computed tomography (CT) and also has the great advantage of not being an invasive method, since it does not use ionizing radiation.The ultrasound (U.S.) and MRI provides images without showing deleterious effects to living organisms, enabling the differentiation between solid and cystic lesions, however, lacks the ability of MRI to provide an anatomical detailing determined, nor information about the chemical composition of the lesions, which would be crucial in determining the diagnosis of the same. The dentigerous cyst is among the most frequent odontogenic lesions that affect the maxillomandibular complex, requiring a thorough assessment of its extent and proximity to anatomical structures as well as the differential diagnosis with other lesions. This study aimed to emphasize the use of MRI and U.S. in the diagnosis of lesions dentomaxilofaciais, describing a clinical case of dentigerous cyst in these imaging modalities were used as complementary tests.
Human umbilical cord vein as a source of osteoblastic cells
Authors: Nascimento Glauce Crivelaro , Bighetti Rayana Longo , Passos Júnior Geraldo Aleixo da Silva , Bombonato-Prado Karina Fittipaldi 
Published: May 2015

Objective: Regenerative medicine and tissue engineering are searching for novel stem cell based therapeutic strategies that will allow for efficient treatment or even potential replacement of damaged organs. The purpose of this work was to study the behaviour of human umbilical cord vein cells (UCVs) through osteoblastic differentiation. Material and Methods: Cells were isolated, expanded and cultivated in osteogenic medium. After 7, 14 and 21 days of culture, there were evaluated cell morphology, proliferation, viability and alkaline phosphatase (ALP) activity. Immunolocalization of ALP was performed after 1, 7 and 14 days of culture and cells were analysed in a fluorescence microscope. Statistical test utilized was Mann-Whitney (p<0.05). Results: The results showed that osteogenic medium induced morphological changes in the UCVs. Besides, it permited cell viability and proliferation, as well as an increase in the alkaline phosphatase expression and activity. Conclusion: It is concluded that these cells can differentiate into osteoblastic-like cells, contributing to applications for cell therapy and tissue engineering.
Comparative evaluation of blood pressure measuring equipment
Authors: Oka Erika Kaori , Fleury Curado Liza Taveira , Santos Lucio Murilo dos , Santamaria Mauro , Moraes Michelle Bianchi , Nascimento Rodrigo Dias , Haldi Fernando Vagner 
Published: May 2015

Objective: This study evaluated the agreement of blood pressure measurements obtained through different auscultatory and oscillometric automated/semi-automated monitors. Material and Methods: The blood pressure of 30 participants was evaluated by a single calibrated examiner. The measurements were carried out through either auscultatory monitor (mercury column or aneroid) or automated/semiautomated oscillometric pulse monitors. For each participant, 5 min rest was established by sitting on dental chair and the measurements were always carried out on the left arm, at the heart level. Three consecutive measurements were performed with the four monitors in each participant with a minimum time interval of five minutes between each measurement. All monitors were properly calibrated and certified by INMETRO. The results were submitted to intraclass correlation coefficient and Friedman’s analysis of variance. Results: The measurements of systolic blood pressure for both auscultatory and oscillometric methods were similar. The measurements of diastolic blood pressure for auscultatory monitors were similar (p > 0.05); as well as for oscillometric monitors (p > 0.05). However, when auscultatory and oscillometric monitors were compared, there were statistically significant differences in diastolic blood pressure (p < 0.05). Conclusion: It was verified a difference in the results between the auscultatory and oscillometric blood pressure monitors. The systolic blood pressure measurements exhibited similar correlations, whilediastolic blood pressure measurements showed different correlations.
Methodology of problematization with the maguerez’s arch: an alternative method for teaching, research and study in dentistry
Authors: Rêgo Heleine Maria Chagas , Rodrigues José roberto 
Published: May 2015

Objective: evaluate the application of the problematization methodology(PM) (Arch Maguerez), as an alternative teaching-learning method in formation post-graduation students. Material and Methods: 25 post-graduate students of the program in Restorative Dentistry at the School of Dentistry of ICT-Office of Science and Technology of São José dos Campos, São Paulo State University – UNESP, who were part of the discipline of Applied Teaching Higher Education , developed activities that characterized the problematization methodology (PM) and the traditional teaching methodology in force. By means of a questionnaire it was possible to assess the perception the students had of the activities made. Results: It was observed that problematization methodology (PM) was a valid alternative teaching-learning method for formation of new professors, in the opinion of students. Conclusion: problematization methodology (PM) can be applied as a complementary tool in the construction of the future professors’ knowledge, in addition to being a strategy for research and study.