bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tongue coblation via the ventral approach for obstructive sleep apnea–hypopnea syndrome surgery
Authors: Hou Tiening , Hu Sunhong , Jiang Xiaohua 
Published: September 2012

AbstractObjectives/Hypothesis:To determine the safety and efficacy of tongue Coblation via the ventral approach in the treatment of hypopharyngeal obstruction for patients with obstructive sleep apnea–hypopnea syndrome (OSAHS).Study Design:Prospective case–control study.Methods:Tongue Coblation was performed under local anesthesia in one session in 40 inpatients diagnosed with OSAHS with predominant hypopharyngeal obstruction after failed uvulopalatopharyngoplasty. In the ventral approach (n = 20), only one puncture point was applied at the center of lingual frenulum, and 12 radiofrequency volumetric tissue reduction (RFVTR) lesions were implanted in the tongue. In the dorsal approach (n = 20), eight RFVTR lesions were distributed on the tongue. Using portable polysomnography (PSG) and the Epworth sleepiness questionnaire (ESQ), we followed 36 patients for 1 year after the operation. Good outcome was defined as apnea–hypopnea index <20 or reduction >50%.Results:In the ventral approach, total energy was accumulated to 23,000 J in 12 lesions, with postoperative pain 2–3 by visual analog scale (VAS). There was only one case of moderate venous bleeding and hematoma. The ESQ comparison indicated subjective improvements in patients, and PSG showed a curative effect in 11 of 19 (61.11%, eight of 19 success plus three of 19 responders), with a failure rate of eight of 19. By contrast, in the dorsal approach, total energy was 16,000 J, with postoperative pain 3–4 (VAS). Complications included mild to moderate tongue venous hematoma, severe infection of tongue, and temporary mild glossal deviation. A curative effect was seen in six of 17, with a failure rate of 11 of 17.Conclusions:Tongue Coblation via the ventral approach is an effective and safe technique to treat hypopharyngeal obstruction in OSAHS surgery. Laryngoscope, 2012
Primary surgical treatment of T3 glottic carcinoma: Long‐term results and decision‐making aspects
Authors: Mantsopoulos Konstantinos , Psychogios Georgios , Bohr Christopher , Zenk Johannes , Kapsreiter Markus , Waldfahrer Frank , Iro Heinrich 
Published: September 2012

AbstractObjectives/Hypothesis:The aim of this study was to assess the efficacy of primary surgical treatment in the management of T3 glottic carcinomas.Study Design:Retrospective clinical study.Methods:A retrospective evaluation of the records for all patients treated with primary surgery for T3 glottic carcinomas at a tertiary referral center between 1980 and 2005 was carried out. Data for the 5‐year disease‐specific survival (DSS) were assessed, as well as local control rates in relation to vocal cord immobility, N classification, choice of surgical modality, and adjuvant therapy. Patients who underwent partial laryngectomy were also evaluated in relation to organ preservation and the rate of permanent tracheotomies.Results:The 5‐year DSS in the 120 patients was 78.3%. Positive neck disease was shown to be a significant negative prognostic factor. Organ preservation was achieved in 90.1% of the patients who underwent partial laryngectomy and in 50% of the overall patient group. The occult metastasis rate was 14%.Conclusions:Primary surgical treatment is an effective modality against T3 glottic carcinomas. Partial laryngectomy is a reliable method in carefully selected cases. Low complication rates can be expected. Laryngoscope, 2012
The impact of nimodipine administration combined with nerve‐muscle pedicle implantation on long‐term denervated rat thyroarytenoid muscle
Authors: Nishimoto Kohei , Kumai Yoshihiko , Sanuki Tetsuji , Minoda Ryosei , Yumoto Eiji 
Published: September 2012

AbstractObjectives/Hypothesis:To evaluate the impact of nimodipineon reinnervation of the long‐term denervated rat thyroarytenoid (TA) muscle following nerve‐muscle pedicle flap (NMP) implantation.Study design:Quantitative histologic and physiologic assessments.Methods:Using 120 Wistar rats, we performed NMP implantation at different times after transection of the left recurrent laryngeal nerve (RLN). Sixty animals received nimodipine treatment (NIMO [+] group), and the remaining 60 animals received no nimodipine treatment (NIMO [−] group). As a control, an additional 28 animals were subjected only to transection of the left RLN (DNV group). Subgroups were assigned based on the period after RLN transection (0 [immediate], 8, 16, and 32 weeks). In the DNV group, we assessed histologically the muscle area, axons, neuromuscular junctions (NMJs), and myosin heavy chains (MyHC) type IIA and IIB in the TA muscle. In the NIMO (−) and NIMO (+) groups, histologic assessments and evoked electromyography were performed on the TA muscle at 10 weeks post‐NMP implantation.Results:In 8‐week interval subgroups, the muscle fiber area and the number of NMJs in the NIMO (+) group were significantly greater than in the NIMO (−) group (P < 0.05, each). In the 0‐week and 32‐week interval subgroups, the muscle fiber subtype changed significantly, from IIA to IIB (P < 0.01 and P < 0.05, respectively); and, at all time‐points the muscle fiber area, number of NMJs, and action potentials in the TA muscle tended to be greater in the NIMO (+) group than in the NIMO (−) group.Conclusions:Nimodipine expedited the effects of NMP implantation on reinnervation of the long‐term denervated TA muscle. Laryngoscope, 2012
Room temperature all‐silicon photonic crystal nanocavity light emitting diode at sub‐bandgap wavelengths
Authors: Shakoor Abdul , Lo Savio Roberto , Cardile Paolo , Portalupi Simone L. , Gerace Dario , Welna Karl , Boninelli Simona , Franzò Giorgia , Priolo Francesco , Krauss Thomas F. , Galli Matteo , O'Faolain Liam 
Published: September 2012

AbstractSilicon is now firmly established as a high performance photonic material. Its only weakness is the lack of a native electrically driven light emitter that operates CW at room temperature, exhibits a narrow linewidth in the technologically important 1300–1600 nm wavelength window, is small and operates with low power consumption. Here, an electrically pumped all‐silicon nano light source around 1300–1600 nm range is demonstrated at room temperature. Using hydrogen plasma treatment, nano‐scale optically active defects are introduced into silicon, which then feed the photonic crystal nanocavity to enhance the electrically driven emission in a device via Purcell effect. A narrow ( nm) emission line at 1515 nm wavelength with a power density of is observed, which represents the highest spectral power density ever reported from any silicon emitter. A number of possible improvements are also discussed, that make this scheme a very promising light source for optical interconnects and other important silicon photonics applications.
Preparation of Biomimetic Hydrogels with Controlled Cell Adhesive Properties and Topographical Features for the Study of Muscle Cell Adhesion and Proliferation
Authors: Jun Indong , Kim Seok Joo , Choi Eunpyo , Park Kyung Min , Rhim Taiyoun , Park Jungyul , Park Ki Dong , Shin Heungsoo 
Published: September 2012

AbstractSynthetic substrates with defined chemical and structural characteristics may potentially be prepared to mimic the living ECM to regulate cell adhesion and growth. Hydrogels with cell‐adhesive peptides (0.28 ± 0.03 nmol peptide · cm−2, TTA‐R‐0.5; and 0.91 ± 0.12 nmol peptide · cm−2, TTA‐R‐2.0) and/or micro‐scaled topographical patterns (10, 25, and 80 µm grooves) are prepared using enzymatic polymerization. The adherent morphology and proliferation of C2C12 skeletal myoblasts and human aortic smooth muscle cells (hAoSM) on the hydrogels are studied. The newly developed hydrogels may be useful in investigating the roles of cell adhesion and substrate surface properties in the communication of adherent cells with the ECM. magnified image
Craving for cannabis in patients with psychotic disorder, their non‐affected siblings and healthy controls: psychometric analysis of the obsessive compulsive drug use scale
Authors: Dekker Nienke , Koeter Maarten , Van Den Brink Wim ,   GROUP Investigators
Published: September 2012

AbstractCannabis use is more common in individuals with non‐affective psychotic disorder and their siblings compared to healthy controls. As cannabis use is associated with a greater risk to develop psychotic disorder and an adverse outcome in those who already developed psychosis, it is important to know the role of craving in continued cannabis use and relapse in these vulnerable subjects. Therefore, we examined the validity of the Obsessive Compulsive Drug Use Scale for cannabis (OCDUS‐CAN) in patients with non‐affective psychotic disorder, their siblings, and healthy controls who all used cannabis in the past year. Simultaneous component analysis (SCA) was used to determine component weights that optimally explained the (co)variance of the OCDUS‐CAN variables in these different populations simultaneously. A three‐component SCA solution explained 74.2 % of the total variance, and consisted of well‐interpretable subscales that could be best described as craving/urge, resistance, and impact. Reliability of the subscales was good. The three subscales significantly discriminated between frequent and infrequent cannabis users. Patients scored higher on the craving/urge and impact scale than siblings and controls, which could be related to primary and secondary symptoms of their disorder. The OCDUS‐CAN is well suitable for people with or without vulnerability for psychotic disorder. Copyright © 2012 John Wiley & Sons, Ltd.
Treatment satisfaction and improvement in health‐related quality of life with onabotulinumtoxinA in patients with urinary incontinence due to neurogenic detrusor overactivity
Authors: Sussman David , Patel Vaishali , Del Popolo Giulio , Lam Wayne , Globe Denise , Pommerville Peter 
Published: September 2012

AbstractAimsOnabotulinumtoxinA significantly reduces urinary incontinence (UI) and improves bladder management in patients with neurogenic detrusor overactivity (NDO). We evaluated the impact of onabotulinumtoxinA on patient‐reported outcomes (PROs) in patients with UI due to NDO in a double‐blind, placebo‐controlled study.MethodsPatients with UI due to NDO (from multiple sclerosis or spinal cord injury) were randomized to intradetrusor placebo (n = 92) or onabotulinumtoxinA 200 U (n = 92) or 300 U (n = 91). PROs included Incontinence Quality of Life (I‐QOL) Questionnaire to assess health‐related quality of life (HRQoL), the 16‐item modified Overactive Bladder‐Patient Satisfaction with Treatment Questionnaire (OAB‐PSTQ) to assess treatment satisfaction, and Patient Global Assessment to assess treatment goal achievement.ResultsMean improvement in I‐QOL total score at weeks 6 and 12 was significantly greater with both onabotulinumtoxinA 200 U and 300 U versus placebo (Δ12.3 for 200 U and Δ14.9 for 300 U vs. placebo; P < 0.001), and was clinically meaningful. For those patients who completed the OAB‐PSTQ, improvement in satisfaction at weeks 6 and 12 was significantly greater for onabotulinumtoxinA versus placebo (P < 0.001, all comparisons). At 6 weeks, greater proportions of onabotulinumtoxinA‐treated patients than placebo reported being somewhat or very satisfied (200 U, 77.5% and 300 U, 67.8% vs. placebo, 39.5%), and significant progress toward or complete achievement of primary treatment goal (200 U, 62.9% and 300 U, 61.6% vs. placebo, 16.5%).ConclusionsNDO patients treated with onabotulinumtoxinA 200 or 300 U had significantly greater improvement in HRQoL and greater treatment satisfaction compared with placebo‐treated patients, with no clinically relevant differences between onabotulinumtoxinA doses. Neurourol. Urodynam. 32: 242–249, 2013. © 2012 Wiley Periodicals, Inc.
Differences in urodynamic study variables in adult patients with neurogenic bladder and myelomeningocele before and after augmentation enterocystoplasty
Authors: Vainrib Michael , Reyblat Polina , Ginsberg David A. 
Published: September 2012

AbstractAimsTo evaluate urodynamic parameters in myelomeningocele patients with native bladders and after augmentation, continence rates and check the longevity of these parameters after lower urinary tract (LUT) reconstruction.MethodsA retrospective review of adult myelomeningocele patients with UDS.Results118 adult patients with NGB secondary to myelomeningocele were identified. 58/118 (49.1%) had UDS performed in our clinic: 18/58 (31%) after prior reconstruction (“Augment” group) and 40/58 (69%) during annual urologic follow up (“NoSx” group). Urodyanmic findings after augmentation included: Pdet@MCC 31.1 (1–95) cmH2O, MCC 495.9 ml, NDO in 3/18 (16.7%), mean DLPP 54.0 (48–60) cmH2O and mean ALPP 39.6 (20–110) cmH2O in 5/18 with an incompetent sphincter. Patients in “NoSx” group had the following findings: Pdet@MCC of 39.6 (1–60) cmH2O, MCC 407.5 ml, 18/40 (45%) had NDO, mean DLPP of 48.1 (15–95) cmH2O and mean ALPP = 51 (17–78) cmH2O in 10/40 with incompetent sphincter. In the “NoSx” group, 19/40 (47.5%) had normal bladder compliance. Mean time from the surgery to UDS was 10.4 years. Continent patients in the “NoSx” group had a significantly higher MCC than incontinent patients in the same group (475 vs. 352 ml, P = 0.029). 8/17 (47.1%) continent patients in “NoSx” group had normal UDS.ConclusionsMost patients after augmentation maintain low bladder pressures for more than 10 years. Close long‐term follow up should be maintained, especially in those patients that have not had prior augmentation. Urinary incontinence may be secondary to poor sphincteric function in patients with and without prior augmentation. Moreover, we should continue to follow patients after reconstruction as elevated detrusor pressures can still be seen. Strict follow up after LUT reconstruction still continues to be important. Neurourol. Urodynam. 32: 250–253, 2013. © 2012 Wiley Periodicals, Inc.
Traumatic brain injury increases the risk of female urinary incontinence
Authors: Keller Joseph J. , Liu Shih‐Ping , Lin Herng‐Ching 
Published: September 2012

AbstractAimsAccording to our knowledge, no study has attempted to explore the risk of urinary incontinence (UI) after traumatic brain injury (TBI). This study aimed to examine the relationship between TBI in Taiwanese women and their risk of developing UI.MethodsThe study was based on 2,416 female patients newly diagnosed with TBI together with 12,080 matched enrollees without a history of TBI as a comparison group. All patients were tracked for a 1‐year period from their index date to identify those who developed subsequent UI. The stratified Cox proportional hazards models were performed to compute the risk of UI between groups.ResultsOf 14,496 patients, 104 (4.30%) from the TBI group and 192 (1.59%) from the comparison group had a diagnosis of UI during the follow‐up period. The incidence rate of UI was 4.50 (95% CI: 3.69–5.43) per 100 person‐years in patients with TBI and 1.62 (95% CI: 1.40–1.86) per 100 person‐years in patients without TBI.The stratified Cox proportional analysis showed that after adjusting for socioeconomic status, obesity, hypertension, diabetes, and hysterectomy, the increased UI risk of patients with TBI persisted at about the same level as in the unadjusted analysis (hazard ratio = 2.78; 95% CI = 2.16–3.53). In addition, although patients with severe and moderate TBI had higher incidence rates of UI than patients with mild TBI, the difference did not reach a statistically significant level (P = 0.090).ConclusionsOur results suggest that an increased risk of UI exists at the first year follow‐up in patients with a TBI diagnosis. Neurourol. Urodynam. 32: 354–358, 2013. © 2012 Wiley Periodicals, Inc.
Percolation threshold and conductivity of polymer electrolyte composites: Effect of dispersoid particle size
Authors: Diwan Puja , Chandra Amita 
Published: September 2012

AbstractSilica particles of different diameters (0.007, 0.014, and 44 μm) have been dispersed in polymer electrolyte (PEO:NH4I) to form composites, and their electrical and thermal behavior have been studied. This article reports the occurrence of two peaks in the plot of conductivity as a function of the amount of dispersoid (SiO2). Further, it is shown that the percolation threshold and the extent of maximum conductivity enhancement in the composites depend on the particle size of the dispersoid. The role of degree of crystallinity/amorphicity of the composites in modifying the conductivity of the composites has also been discussed and a phenomenological explanation is being proposed. POLYM. COMPOS., 2012. © 2012 Society of Plastics Engineers
Preparation and characterization of silicone resin nanocomposite containing CdSe/ZnS quantum dots
Authors: Trung Nguyen Ngoc , Luu Quynh‐Phuong , Son Bui Thanh , Sinh Le Hoang , Bae Jin‐Young 
Published: September 2012

AbstractWe report the preparation of the core/shell cadmium selenide/Zinc sulfide quantum dots (CdSe/ZnS QDs)‐silicone resin nanocomposite through the solution‐mixing method, followed by thermal hydrosilylation. After dispersing QDs into Dow Corning two‐component silicone resins (OE6630A and OE6630B at 1:4 mixing ratio by weight), the resins were cured at 150°C for 1.5 h to produce QD‐silicone resin nanocomposites. The curing behavior of the silicone resins resulting from the thermal hydrosilylation was studied using differential scanning calorimetry (DSC). The properties of the QD‐silicone resin nanocomposites were investigated by ultraviolet–visible (UV–vis), fluorescence, confocal laser scanning microscopy (CLSM), atomic force microscopy (AFM), and thermogravimetric analysis (TGA) measurements. The QDs that contain trioctylamine (TOA) as the original ligand can poison the Pt catalyst in the resins and inhibit the curing process by increasing the exothermic peak temperature, at which a lower heat of hydrosilylation is observed. Incorporating a small amount of CdSe/ZnS QDs (0.1 wt%) can greatly improve the thermal stability of the silicone resins. Moreover, CdSe/ZnS QDs tend to form clusters that are relatively homogeneously distributed in a cured silicone resin, offering good optical properties of 11.2 lm W−1 luminous efficiency and 14.6% photoluminescence conversion efficiency (PCE) in light emitting device (LED) test. POLYM. COMPOS., 2012. © 2012 Society of Plastics Engineers
Facile control of morphological characteristics of magnetite aggregates (nFe3O4) by the addition of bifunctional ligands
Authors: Kim Sung‐Eun , Lee Sang‐Wha 
Published: September 2012

AbstractWe demonstrated a facile method to control magnetite clusters with different size and surface morphology by adding bifunctional diamines. First, citrate‐capped magnetites (CFe3O4) were prepared by adding citrate ions into ferrofluid during the co‐precipitation process. The resulting CFe3O4 was subsequently treated by diamine molecules with different chain lengths (C‐4, C‐8, C‐12), consequently leading to the formation of diamine‐linked magnetite aggregates (DnFe3O4) with different size and surface morphology. The longer chain length of diamines increased the particle size of DnFe3O4 due to the enhanced crosslinking between CFe3O4. The excessive addition of C‐4 and C‐12 diamines induced the significant morphological changes from irregular‐shaped CFe3O4 to spherical and rod‐shaped DnFe3O4, respectively. Furthermore, DnFe3O4 retained their initial magnetism under a strong oxidative process, implicating the potential application to recyclable catalyst or active electrode materials in Li‐ion batteries.
A sol–gel approach to self‐formation of microtubular structures from metal alkoxide gel films
Authors: Järvekülg Martin , Välbe Raul , Jõgi Jakob , Salundi Aigi , Kangur Triin , Reedo Valter , Kalda Jaan , Mäeorg Uno , Lõhmus Ants , Romanov Alexey E. 
Published: September 2012

AbstractA technique of preparing microtube shape oxide structures by metal alkoxide gel sheet rolling is presented and discussed. Zr(OBu)4 and Hf(OBu)4 precursors have been used for self‐formation of ZrO2 and HfO2 microrolls. The technique involves gelling the surface of concentrated sol, partition of gel film into segments by gel cracking and spontaneous rolling of obtained gel film segments. A phenomenological study of crack evolution in gel films has been conducted. The dependence of the thickness of formed gel film and rolling diameter on hydrolysis extent of metal alkoxide precursor and reaction time is reported.
Nanostructure–property relations for phase‐change random access memory (PCRAM) line cells
Authors: Kooi B.J. , Oosthoek J.L.M. , Verheijen M.A. , Kaiser M. , Jedema F.J. , Gravesteijn D.J. 
Published: September 2012

AbstractPhase‐change random access memory (PCRAM) cells have been studied extensively using electrical characterization and rather limited by detailed structure characterization. The combination of these two characterization techniques has hardly been exploited and it is the focus of the present work. Particularly, for improving the reliability of PCRAM such combined studies can be considered indispensable. Here, we show results for PCRAM line cells after series of voltage pulses with increasing magnitude are applied, leading to the first minimum sized amorphous mark, maximum amorphous resistance and over‐programming, respectively. Furthermore, the crucial effect of electromigration limiting the endurance (cyclability) of the cells is demonstrated.
Peri‐eutectic transition during crystallization of undercooled ternary alloy melt
Authors: Ruan Y. 
Published: September 2012

AbstractPeri‐eutectic transition was investigated in terms of the dependence of crystallization behavior on undercooling in Cu–Ag–Ge ternary alloy composed of (Ag), ζ(Cu5Ge), and ε2(Cu3Ge) phases. (Ag + ε2) pseudobinary eutectic is the product of both peri‐eutectic and subsequent pseudobinary eutectic transitions. Nanoscale structure of anomalous (Ag + ε2) pseudobinary eutectic forms at the maximum undercooling, which is ascribed to the independent nucleation and growth from the liquid. The decrease of (Ag + ε2) pseudobinary eutectic at a high undercooling is due to that the phase transition happening at the beginning solidification stage proceeds more thoroughly at a higher undercooling.
Crystallization kinetics and thermal stability in Ge–Sb–Se glasses
Authors: Wei Wen‐Hou , Fang Liang , Shen Xiang , Wang Rong‐Ping 
Published: September 2012

AbstractThe crystallization kinetics of Ge–Sb–Se chalcogenide glasses prepared by melt‐quenching method was investigated using differential scanning calorimetry under non‐isothermal conditions with several different heating rates. Kissinger's equation and Matusita model were employed to analyze kinetic crystallization behavior of the glasses. The crystallization parameters were calculated and the crystallization mechanism was studied. The results indicate that the crystallization activation energy increases rapidly at the glass with a mean coordination number (MCN) of 2.4, and reaches its maximum at MCN of 2.65. These two transition thresholds correspond to the structural phase transition in the glassy network. The evolution of the glass transition temperature (Tg), activation energy for crystallization (Ec), glass forming ability and thermal ability as functions of MCN and chemical composition might have substantial implication on screening the best glass for the application in photonics.