bluuebunny/crossref_metadata_2025_split huggingface dataset:
Co-relating HbA1c and serum IgA in diabetic and non-diabetic patients with and without periodontitis
Authors: Deepti Chaurasia , Reena Kulshrestha , Pooja Sitholay , Gopinath V. , Rohit Agrawal , Vijayta Sharva 
Published: October 2014

Objective: Diabetics are more susceptible to the infections than the non-diabetics (healthy) one, suggesting that the immunologic capability may be unbalanced in diabetics. Periodontitis is associated with alterations in immune responses in both diabetic and non-diabetic subjects. Till date various attempts has been taken to monitor host immunological response of diabetic individuals. Therefore the need to study the local immune response in inflamed gingival showing Periodontitis is apparent. Since till date there are no well documented and significant baseline studies are available on the functional capacities of the lymphoid cells present in gingiva of the periodontitis patients, a study to check the level of immunoglobulin was investigated. Methodology: A study was carried out where HbA1c, Random Blood Sugar and Serum IgA level were assessed in 60 patients from the OPD of RCDSR. 15 patients each belonging to the four groups diabetic with periodontitis, diabetic without periodontitis, non-diabetic with periodontitis and non- diabetic without periodontitis (control) were analysed for the quantitative estimation of Serum Immunoglobulin A by Turbidometric Immunoassay and HbA1c was done by using Nyco card Reader.Result: The data thus obtained were compared with the level of immunoglobulin found in clinically healthy gingival of the control group. The levels of IgA were found to be high in group ‘A’ (Diabetic patients suffering from Periodontitis) group ‘B’ (Diabetic patients not suffering from Periodontitis) and group ‘C’ (Non-diabetic patients suffering from Periodontitis) but the values are not differing statistically from each other. But, the values of all these groups are statistically highly differed from the value obtained against the normal/healthy controlled group ‘D’. Conclusion: In our study it can be concluded that there was positive co-relation between the two parameters: elevated HbA1c and Immunoglobulin level with periodontitis. This co-relates to the possibility of an underlying immuno-inflammatory abnormality to be the cause for the elevated level of immunoglobulin in our patients with elevated sugar level. DOI: http://dx.doi.org/10.3126/ajms.v6i2.11096Asian Journal of Medical Sciences Vol.6(2) 2015 72-77
Isolated Pulmonary Metastasis from Prostate Adenocarcinoma: Diagnosis by Fine Needle Aspiration Cytology
Authors: Khairwa Anju , Nalini Gupta , Manphool Singhal , Santosh Kumar , Arvind Rajwanshi 
Published: October 2014

Prostate cancer usually metastasizes to regional lymph nodes and bone followed by distant organs. Here, we present a case of elderly man who had isolated respiratory symptoms and finally turned out to be metastasis from prostate cancer. Rarity of isolated pulmonary metastases of prostate cancer without bone and lymph node involment prompted us to report this case which was diagnosed by CT guided FNAC. DOI: http://dx.doi.org/10.3126/ajms.v6i2.11103Asian Journal of Medical Sciences Vol.6(2) 2015 111-114
Free PSA: A better molecular marker than total PSA for breast cancer
Authors: Nanda Rachita 
Published: October 2014

Serum total PSA (prostate specific antigen) has been considered since some time for diagnosis or prognosis of breast cancer. PSA is present both as free and complexed form. Many researchers have shown total PSA increases in all forms of breast disease, whether cancerous or benign lesions. Few scientists have demonstrated that the free form of PSA is the predominant form in breast cancer.1,2 Also the observation that there is a marginal reduction in total PSA after surgery in comparison to a remarkable decrease in free PSA is a strong indicator that a large portion of total PSA is produced by normal tissue and that free PSA is produced by breast tumors.3,4,5 Moreover free PSA as the predominant form was found to be highly specific for breast cancer when compared to benign and normal tissues.3 In India, Dash et al.,(2011) in their study in Indian population observed similar results using total and free PSA in patients of breast tumors 5 augmenting its role as a prognostic marker. With a heterogeneous study population in India where breast cancer is commonly encountered, population based studies are essential to study the molecular forms of PSA with respect to the disease process like relapse or metastasis and therefore with future treatment. DOI: http://dx.doi.org/10.3126/ajms.v6i2.11110Asian Journal of Medical Sciences Vol.6(2) 2015 129
Active lakes of Recovery Ice Stream, East Antarctica: a bedrock-controlled subglacial hydrological system
Authors: Fricker Helen Amanda , Carter Sasha P. , Bell Robin E. , Scambos Ted 
Published: October 2014

AbstractA connected system of active subglacial lakes was revealed beneath Recovery Ice Stream, East Antarctica, by ICESat laser altimetry. Here we combine repeat-track analysis of ICESat (2003–09), Operation IceBridge laser altimetry and radio-echo sounding (2011 and 2012), and MODIS image differencing (2009–2011) to learn more about the lake activity history, the surface and bedrock topographic setting of the lakes and the constraints on water flow through the system. We extend the lake activity time series to 2012 for the three lower lakes and capture two major lake drainages. One lake underwent a large deflation between 2009 and 2011 while another lake, which had been continuously filling between 2003 and 2010, started to drain after 2011. Most of the active lakes are located in a ~ 1000 km long bedrock trough under the main trunk of Recovery Ice Stream, whose base is ~ 1500– 2000 m below present-day sea level. The hydrologic system beneath Recovery Ice Stream is controlled by this unusually pronounced bedrock topography, in contrast to most Antarctic systems studied to date, which are controlled by the ice surface topography. Hydrologic connections among the lakes appear to be direct and responsive, and we reproduce the lake activity using a simple subglacial water model. We discuss potential causes of non-steady hydrologic behavior in major Antarctic catchments.
Brève histoire de la Société suisse de psychanalyse
Authors: Moser Alexander 
Published: October 2014

Les Suisses étaient des psychanalystes de la première heure grâce, avant tout, à une psychiatrie progressiste autour des psychiatres Auguste-Henri Forel et Eugène Bleuler. Freud a salué les nombreux disciples aux nationalités diverses – plus tard mondialement connus – qui lui venaient de la Suisse. Mais plus tard, beaucoup de Suisses choisirent leur propre chemin, provoquant même des scissions, et même s’ils restaient membres de la ssp sa, ils ne se soumettaient pas à une seule école étroite dominante ; ils ont conservé une formation relativement libérale jusqu’à aujourd’hui, avec une remarquable diversité d’opinions théoriques et pratiques.
Perturbed Angular Correlation Study of the Static and Dynamic Aspects of Cadmium and Mercury Atoms Inside and Attached to a C60 Fullerene Cage
Authors: Das Satyendra K. , Guin Rashmohan , Banerjee Debasish , Johnston Karl , Das Parnika , Butz Tilman , Amaral Vitor S. , Correia Joao G. , Barbosa Marcelo B. 
Published: October 2014

Abstract
30 keV 111mCd and 50 keV 199mHg beams from ISOLDE were used to implant on preformed targets of C60 with a thickness of 1 mg cm-2. Endofullerene compounds, viz. 111mCd@C60 and 199mHg@C60 formed during implantation were separated by filtration through micropore filter paper followed by solvent extraction. Dried samples of the endofullerene compounds were counted for the time differential perturbed angular correlation (TDPAC) measurement using the coincidence of the 151 - 245 keV cascade of 111mCd and the 374 - 158 keV cascade of 199mHg on a six LaBr3(Ce) detector system coupled with digital electronics. The results for 111mCd@C60 indicate a single static component (27%) and a fast relaxing component (73%), the latter implying that the cadmium atom moves rapidly inside the cage at room temperature. The quadrupole interaction frequency and asymmetry parameter of the cadmium atom occupying the static site in C60 are wQ=8.21(36) Mrad s-1 and η = 0.41(9), respectively. The fast relaxation constant is 0.0031(4) ns-1. Similarly, mercury atoms also exhibit a single static and a fast component. The static site has a quadrupole frequency wQ=283.0(12.4) Mrad s-1 and η =0 with a fraction of 30%. The fast relaxation constant is 0.045(8) ns-1 with a fraction of 70%, very similar to that of cadmium.
The Ignition of Cylindrical Fusion Targets by Multi-Mega-Ampere GeV Proton Beams below the Alfvén Limit
Authors: Winterberg Friedwardt 
Published: October 2014

Abstract
It is shown that cylindrical deuterium targets can be ignited with multi-mega-ampere GeV proton beams below the Alfvén limit and a small amount of tritium. The proton beams can be generated by discharging a magnetically insulated gigavolt capacitor. Surrounding the thermonuclear microexplosion with a thick layer of liquid hydrogen, heated to a ~ 105 K plasma by the thermalization of the fusion reaction neutrons, most of the energy released can be converted into electric energy by a magnetohydrodynamic generator.
Thermodynamics of a quantum dissipative charged magneto‐oscillator
Authors: Kumar Jishad 
Published: October 2014

Quantum dissipative effect on the thermodynamics of an electron in the combined presence of a parabolic potential and a uniform (and homogeneous) magnetic field, is investigated here. Starting from the microscopic system plus bath model, we explicitly derive the thermodynamic properties using the reduced partition function of the system which is calculated using the imaginary time path integral method. The quantum heat bath we consider here is a structured heat bath whose spectral density corresponds to a structured thermal harmonic noise. All the statistical thermodynamic functions calculated do reconcile with the requirements of the fundamental axioms of physics. In particular, the specific heat and the entropy vanishes as the temperature approaches its absolute zero value, a necessity of the third law of thermodynamics. Moreover the specific heat satisfies classical equipartition theorem at high temperatures. The coefficients of the leading temperature dependent terms of the thermodynamic quantities depend only on the damping constant but not on other parameters of the bath spectral density, which is similar to the analysis based on the Drude bath spectral density. Our study facilitates the physics of small quantum systems, which are always in contact with some environments, at very low temperatures.image
Phototunable Liquid‐Crystalline Phases Made of Nanoparticles
Authors: Zep Anna , Wojcik Michal M. , Lewandowski Wiktor , Sitkowska Kaja , Prominski Aleksander , Mieczkowski Jozef , Pociecha Damian , Gorecka Ewa 
Published: October 2014

AbstractThe properties of liquid‐crystalline (LC) hybrid systems made of inorganic nanoparticles grafted with photosensitive azo compounds are presented. For materials with a large density of azo ligands at the surface, the LC structure can be reversibly melted by UV light, and the return to the LC state does not require the absorption of visible light. For systems with a lower density of azo ligands, UV light causes shortening of the distance between metal sublayers in the lamellar phase. Interestingly, the azo derivatives attached to the nanoparticle surface show very different kinetics of cis/trans conformational change as compared to the free molecules. The cis form of free ligands in solution is stable for days, whereas the isomerization of molecules attached to the nanoparticle surface to the trans form takes only a few minutes. Apparently, owing to the crowded environment, azo ligands immobilized at a metal surface behave as they would in the condensed state.
Lagrangian simulation and analysis of the micromixing phenomena in a cylindrical paddle mixer using a modified weakly compressible smoothed particle hydrodynamics method
Authors: Shamsoddini Rahim , Sefid Mohammad , Fatehi Rouhollah 
Published: October 2014

AbstractIn the present study, a robust modified weakly compressible smoothed particle hydrodynamics (SPH) method is introduced in order to examine the micromixing phenomena within a cylindrical paddle mixer. Because it has a Lagrangian nature and it is based on particles, smoothed particle hydrodynamics is an appropriate and convenient method for simulating the moving boundary problems and tracking the particles in the mixing process. The present study thus introduces a convenient SPH method for modelling the mixing process. The straight and cross‐shaped blades are considered, and the effects of the fixed rotation, planetary motion of the blade, and position of the blade on the mixing rate are studied. © 2014 Curtin University of Technology and John Wiley & Sons, Ltd.
Effect of various efficient vulcanization cure systems on the compression set of a nitrile rubber filled with different fillers
Authors: Movahed Saeed Ostad , Ansarifar Ali , Mirzaie Farnaz 
Published: October 2014

ABSTRACTEffect of various efficient vulcanization (EV) sulfur cure systems on the compression set of a nitrile rubber filled with carbon black and silica/silane fillers was examined. The cure systems had different amounts of thiuram and sulfenamide accelerators and elemental sulfur, whilst the loading of zinc oxide and stearic acid activators was kept constant. The fillers had surface areas from 35 to 175 m2/g. In this study, the lowest compression set was measured for the rubber filled with carbon black with 78 m2/g surface area, which was cured with an EV cure system made of a small amount of elemental sulfur and large amounts of the two accelerators. Interestingly, a small change in the amount of elemental sulfur had a bigger effect on the compression set than did large changes in the loading of the accelerators in the cure system. Among the fillers, carbon black caused less compression set of the rubber vulcanizate than the silica/silane system did. © 2014 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2015, 132, 41512.
Effect of primary structure on permselectivity of ultrathin semipermeable polybenzimidazole membrane
Authors: Aiba Motohiro , Tokuyama Takahiro , Matsumoto Hidetoshi , Tomioka Hiroki , Higashihara Tomoya , Ueda Mitsuru 
Published: October 2014

ABSTRACTA series of polybenzimidazoles (PBIs) with different main chains and sulfonated PBI were successfully synthesized from the corresponding dicarboxylic acids and 3,3'‐diaminobenzidine for the formation of ultrathin, single‐component, and semipermeable membranes. Furthermore, the covalently crosslinked PBI membrane was prepared by the reaction of sulfonated PBI with divinyl sulfone. Their water transport properties were evaluated under a reverse osmosis mode and compared with the primary structure based on the water permeability (A) and salt permeability (B) values normalized by the membrane thickness. It was found that the A and B values of the PBIs were improved with increasing the weight ratio of the imidazole rings per repeating unit, the introduction of sulfonate group as the hydrophilic group to the PBI was an effective way to enhance the A value, and the crosslinked structure enhanced the salt rejection rate (R) value while maintaining the water flux. © 2014 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2015, 132, 41531.
Phosphorescent Cyclometalated Iridium(III) Complexes That Contain Substituted 2‐Acetylbenzo[b]thiophen‐3‐olate Ligand for Red Organic Light‐Emitting Devices
Authors: Yang Chen , Lai Shiu‐Lun , Chan Sharon Lai‐Fung , Low Kam‐Hung , Cheng Gang , Yeung Kwan‐Ting , Kwok Chi‐Chung , Che Chi‐Ming 
Published: October 2014

AbstractWe report the synthesis of a new class of thermally stable and strongly luminescent cyclometalated iridium(III) complexes 1–6, which contain the 2‐acetylbenzo[b]thiophene‐3‐olate (bt) ligand, and their application in organic light‐emitting diodes (OLEDs). These heteroleptic iridium(III) complexes with bt as the ancillary ligand have a decomposition temperature that is 10–20 % higher and lower emission self‐quenching constants than those of their corresponding complexes with acetylacetonate (acac). The luminescent color of these iridium(III) complexes could be fine‐tuned from orange (e.g., 2‐phenyl‐6‐(trifluoromethyl)benzo[d]thiazole (cf3bta) for 4) to pure red (e.g., lpt (Hlpt=4‐methyl‐2‐(thiophen‐2‐yl)quinolone) for 6) by varying the cyclometalating ligands (C‐deprotonated C^N). In particular, highly efficient OLEDs based on 6 as dopant (emitter) and 1,3‐bis(carbazol‐9‐yl)benzene (mCP) as host that exhibit stable red emission over a wide range of brightness with CIE chromaticity coordinates of (0.67, 0.33) well matched to the National Television System Committee (NTSC) standard have been fabricated along with an external quantum efficiency (EQE) and current efficiency of 9 % and 10 cd A−1, respectively. A further 50 % increase in EQE (>13 %) by replacing mCP with bis[4‐(6H‐indolo[2,3‐b]quinoxalin‐6‐yl)phenyl]diphenylsilane (BIQS) as host for 6 in the red OLED is demonstrated. The performance of OLEDs fabricated with 6 (i.e., [(lpt)2Ir(bt)]) was comparable to that of the analogous iridium(III) complex that bore acac (i.e., [(lpt)2Ir(acac)]; 6 a in this work) [Adv. Mater.­ 2011, 23, 2981] fabricated under similar conditions. By using ntt (Hnnt=3‐hydroxynaphtho[2,3‐b]thiophen‐2‐yl)(thiophen‐2‐yl)methanone) ligand, a substituted derivative of bt, the [(cf3bta)2Ir(ntt)] was prepared and found to display deep red emission at around 700 nm with a quantum yield of 12 % in mCP thin film.
Proteins without unique 3D structures: Biotechnological applications of intrinsically unstable/disordered proteins
Authors: Uversky Vladimir N. 
Published: October 2014

AbstractIntrinsically disordered proteins (IDPs) and intrinsically disordered protein regions (IDPRs) are functional proteins or regions that do not have unique 3D structures under functional conditions. Therefore, from the viewpoint of their lack of stable 3D structure, IDPs/IDPRs are inherently unstable. As much as structure and function of normal ordered globular proteins are determined by their amino acid sequences, the lack of unique 3D structure in IDPs/IDPRs and their disorder‐based functionality are also encoded in the amino acid sequences. Because of their specific sequence features and distinctive conformational behavior, these intrinsically unstable proteins or regions have several applications in biotechnology. This review introduces some of the most characteristic features of IDPs/IDPRs (such as peculiarities of amino acid sequences of these proteins and regions, their major structural features, and peculiar responses to changes in their environment) and describes how these features can be used in the biotechnology, for example for the proteome‐wide analysis of the abundance of extended IDPs, for recombinant protein isolation and purification, as polypeptide nanoparticles for drug delivery, as solubilization tools, and as thermally sensitive carriers of active peptides and proteins.
Towards the Efficient Development of Homogeneous Catalytic Transformation to γ‐Valerolactone from Biomass‐Derived Platform Chemicals
Authors: Dutta Chowdhury Abhishek , Jackstell Ralf , Beller Matthias 
Published: October 2014

AbstractRecent efforts focused on the production of selected chemicals from biomass as an effective approach to replace fossil feedstocks. Among them, transformation of the biogenic platform molecule levulinic acid to γ‐valerolactone has been an extensively studied reaction. Although this transformation can be achieved by heterogeneous catalysis, there exists also a strong interest for effective homogeneous catalysis that can operate selectively under milder and sustainable conditions. Herein, we report the utilization of various triphos‐analogue ligands that in the presence of Ru(acac)3 (acac=acetylacetonate) lead to highly efficient γ‐valerolactone production (yield up to 95 %). Excellent catalyst turnover numbers (up to 75 855) and turnover frequencies (up to 1382 h−1) were accomplished.
Applicability of Metals as Liner Materials for Ammonoacidic Crystal Growth
Authors: Hertweck Benjamin , Zhang Shiyu , Steigerwald Thomas G. , Alt Nicolas S. A. , Niewa Rainer , Schluecker Eberhard 
Published: October 2014

AbstractThe ammonoacidic crystal growth allows industrial production of bulk semiconductor materials like gallium nitride as a widely known material for applications in photonics. A limitation of this process is strong corrosion of the growth autoclave which consequently leads to high impurity density in grown crystals, even if the autoclave is partly lined with state‐of‐the‐art systems. Innovative metallic liner technologies are evaluated which allow a complete lining of the autoclave and peripheral parts. In this way, bridging the gap between fundamental research regarding the corrosive degeneration of possible liner materials and the implementation of novel lined autoclaves for improved growth conditions. Screening tests to find suitable materials and evaluate its potential for development of a liner technology are described.
High‐Performance Bioanode Development for Fermentable Substrates via Controlled Electroactive Biofilm Growth
Authors: Ichihashi Osamu , Vishnivetskaya Tatiana A. , Borole Abhijeet P. 
Published: October 2014

AbstractA bioanode was optimized to generate current densities reaching 38.4±4.9 A m−2, which brings bioelectrochemical systems closer to commercial consideration. Glucose and lactate were fed together in a continuous or fed‐batch mode. The current density increased from 2.3 A m−2 to 38.4 A m−2 over a 33 day period and remained stable thereafter. The Coulombic efficiency ranged from 50 % to 80 %. A change in substrate concentration from 200 mg L−1 to 5 mg L−1 decreased maximum current density from 38.4 A m−2 to 12.3 A m−2. The anode consortia included Firmicutes (55.0 %), Proteobacteria (41.8 %) and Bacteroidetes (2.1 %) constituting two potentially electrogenic genera: Geobacter (6.8 %) and Aeromonas (31.9 %). The current production was found to be limited by kinetics during the growth period (33 days), and mass transfer, thereafter. The results indicate the necessity of removing spent biomass for efficient long‐term operation and treatment of wastewater streams.
Conformationally Restricted Isoindoline‐Derived Spin Labels in Duplex DNA: Distances and Rotational Flexibility by Pulsed Electron–Electron Double Resonance Spectroscopy
Authors: Gophane Dnyaneshwar B. , Endeward Burkhard , Prisner Thomas F. , Sigurdsson Snorri Th. 
Published: October 2014

AbstractThree structurally related isoindoline‐derived spin labels that have different mobilities were incorporated into duplex DNA to systematically study the effect of motion on orientation‐dependent pulsed electron–electron double resonance (PELDOR) measurements. To that end, a new nitroxide spin label, ExImU, was synthesized and incorporated into DNA oligonucleotides. ExImU is the first example of a conformationally unambiguous spin label for nucleic acids, in which the nitroxide NO bond lies on the same axis as the three single bonds used to attach the otherwise rigid isoindoline‐based spin label to a uridine base. Continuous‐wave (CW) EPR measurements of ExImU confirm a very high rotational mobility of the spin label in duplex DNA relative to the structurally related spin label ImU, which has restricted mobility due to an intramolecular hydrogen bond. The X‐band CW‐EPR spectra of ExImU can be used to identify mismatches in duplex DNA. PELDOR distance measurements between pairs of the spin labels ImU, OxU, and ExImU in duplex DNA showed a strong angular dependence for ImU, a medium dependence for OxU, and no orientation effect for ExImU. Thus, precise distances can be extracted from ExImU without having to take orientational effects into account.