bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multinational Randomized Phase III Trial With or Without Consolidation Chemotherapy Using Docetaxel and Cisplatin After Concurrent Chemoradiation in Inoperable Stage III Non–Small-Cell Lung Cancer: KCSG-LU05-04
Authors: Ahn Jin Seok , Ahn Yong Chan , Kim Joo-Hang , Lee Chang Geol , Cho Eun Kyung , Lee Kyu Chan , Chen Ming , Kim Dong-Wan , Kim Hoon-Kyo , Min Young Joo , Kang Jin-Hyoung , Choi Jin-Hyuck , Kim Sang-We , Zhu Guangying , Wu Yi-Long , Kim Sung Rok , Lee Kyung Hee , Song Hong Suk , Choi Yoon-La , Sun Jong-Mu , Jung Sin-Ho , Ahn Myung-Ju , Park Keunchil 
Published: July 2015

Purpose To determine the efficacy of consolidation chemotherapy (CC) with docetaxel and cisplatin (DP) after concurrent chemoradiotherapy (CCRT) with the same agents in locally advanced non–small-cell lung cancer (LA-NSCLC). Patient and Methods Patients were randomly assigned to either CCRT alone (observation arm) or CCRT followed by CC (consolidation arm). CCRT with docetaxel (20 mg/m2) and cisplatin (20 mg/m2) was administered every week for 6 weeks with a total dose of 66 Gy of thoracic radiotherapy in 33 fractions. In the consolidation arm, patients were further treated with three cycles of DP (35 mg/m2 each on days 1 and 8, every 3 weeks). The primary end point was 40% improvement in progression-free survival (PFS) compared with observation. Results From October 2005 to April 2011, 437 patients were randomly assigned. Seventeen patients did not start CCRT as a result of consent withdrawal or ineligibility reasons after random assignment, leaving 420 patients for this analysis (n = 211 for observation; n = 209 for consolidation). Patient characteristics were similar in both arms. In the consolidation arm, 143 patients (68%) received CC, of whom 88 (62%) completed three planned cycles. The median PFS was 8.1 months in the observation arm and 9.1 months in the consolidation arm (hazard ratio, 0.91; 95% CI, 0.73 to 1.12; P = .36). Median overall survival times were 20.6 and 21.8 months in the observation and consolidation arms, respectively (HR, 0.91; 95% CI, 0.72 to 1.25; P = .44). Conclusion CC with DP after CCRT with weekly DP in LA-NSCLC failed to further prolong PFS. CCRT alone should remain the standard of care.
Eye movements in chameleons are not truly independent – evidence from simultaneous monocular tracking of two targets
Authors: Katz Hadas Ketter , Lustig Avichai , Lev-Ari Tidhar , Nov Yuval , Rivlin Ehud , Katzir Gadi 
Published: July 2015

ABSTRACT
Chameleons perform large-amplitude eye movements that are frequently referred to as independent, or disconjugate. When prey (an insect) is detected, the chameleon's eyes converge to view it binocularly and ‘lock’ in their sockets so that subsequent visual tracking is by head movements. However, the extent of the eyes’ independence is unclear. For example, can a chameleon visually track two small targets simultaneously and monocularly, i.e. one with each eye? This is of special interest because eye movements in ectotherms and birds are frequently independent, with optic nerves that are fully decussated and intertectal connections that are not as developed as in mammals. Here, we demonstrate that chameleons presented with two small targets moving in opposite directions can perform simultaneous, smooth, monocular, visual tracking. To our knowledge, this is the first demonstration of such a capacity. The fine patterns of the eye movements in monocular tracking were composed of alternating, longer, ‘smooth’ phases and abrupt ‘step’ events, similar to smooth pursuits and saccades. Monocular tracking differed significantly from binocular tracking with respect to both ‘smooth’ phases and ‘step’ events. We suggest that in chameleons, eye movements are not simply ‘independent’. Rather, at the gross level, eye movements are (i) disconjugate during scanning, (ii) conjugate during binocular tracking and (iii) disconjugate, but coordinated, during monocular tracking. At the fine level, eye movements are disconjugate in all cases. These results support the view that in vertebrates, basic monocular control is under a higher level of regulation that dictates the eyes’ level of coordination according to context.
Maximal regularity in exponentially weighted Lebesgue spaces of
the Stokes operator in unbounded cylinders
Authors: Ri Myong-Hwan , Farwig Reinhard 
Published: July 2015

Abstract
We study resolvent estimates and maximal regularity of the Stokes operator in Lq
-spaces with
exponential weights in the axial directions of unbounded cylinders of ℝ
n
, n ≥ 3.
For a straight cylinder we use exponential weights in the axial direction
and Muckenhoupt weights in the cross-section.
Next, for cylinders with several exits to infinity we prove that the Stokes
operator in Lq
-spaces with exponential weights
generates an exponentially decaying analytic semigroup and has maximal regularity.
The proof for straight cylinders uses an operator-valued Fourier multiplier theorem and
unconditional Schauder decompositions based on the
ℛ-boundedness of the family of solution operators
for a system in the cross-section of the cylinder parametrized by the phase variable
of the one-dimensional partial Fourier transform.
For general cylinders we use cut-off techniques based on the result
for straight cylinders and the case without exponential weight.
Dynamische Echtzeit-Optimierung der Substratzufuhr für anaerobe Co-Vergärungsanlagen
Authors: Gaida Daniel 
Published: July 2015

Zusammenfassung
Um Biogas bedarfsgerecht zu produzieren, ist eine optimale Regelung der Substratzufuhr auf
Biogasanlagen notwendig. Für Co-Vergärungsanlagen ergibt sich ein multikriterielles, dynamisches
Optimierungsproblem, welches in Echtzeit gelöst werden muss. In dieser Dissertation wird ein potenzieller
Lösungskandidat entwickelt und in Simulationsstudien evaluiert.
Residues of standard intertwining operators on p-adic classical groups
Authors: Yu Xiaoxiang 
Published: July 2015

Abstract
We study two basic problems involved in the study of the
standard intertwining operators attached to representations
induced from irreducible unitary supercuspidal representations on
maximal parabolic subgroups of p-adic classical groups. We give a formula to
transfer the integrals over the unipotent radical to orbital integrals under the
adjoint action of the Levi subgroup, and conclude that the residue of such standard
intertwining operators at

s
=
0

${s=0}$

is determined by compact orbital integrals.
Informationsfluss in Organisationen. Theorien zum Informationstransfer und historische Praxis
Authors: Barjot Dominique , Schröter Harm G. 
Published: July 2015

Abstract
The transfer of information is a key function of any organization. Whether reflected and designed or not, systems emerge for this transfer. Like the nervous system of the human body, an information system is vital to any organization. How these systems function is of great importance. Well functioning systems are linked to success while a malfunction may lead to decline or even disaster. Though the relevance of information systems was not questioned in principle, they used to play a minor role in the writing of history. This lack of research is one main reason for this introduction; the other is to provide a short overview over the development of theories of information systems.
Brokering Trust: The Construction of Transnational Family Business Networks, 1980-2010
Authors: Puig Nuria 
Published: July 2015

Abstract
Family capitalism became considerably empowered over the three decades prior to the great recession in 2008. This article argues that the construction of transnational family business networks through the coordinated action of individuals and institutions was crucial to the overall legitimization of family capitalism. The rise of a family business institutional infrastructure in the United States and its creative translation into the European context are first described and then analysed in the light of organizational communication theory. Building on the communication as constitutive of organizations view (CCO) and on Casson’s studies on the economics of trust, the article shows that interpersonal and inter-organizational trust and communication played a key role in the institutionalization of family business on both sides of the Atlantic. Consultants and the other drivers of this fascinating process acted primarily as trust brokers, helping to reduce transaction and information costs and bridge the gap between business owners, external professionals, and society. Finally, the story of the family business movement confirms that elites can easily manage cultural differences to engage in transnational networking. However, structural differences between US and European networks suggest that national institutional settings strongly influence communication among interest groups and its organizational outcome.
Communication in Inter-firm Network: Guest Engineers and Knowledge Transfer in the Japanese Automobile Industry after the Second World War
Authors: Kono Hideko 
Published: July 2015

Abstract
This study examines communication in a system of inter-firm networks and the dynamics of knowledge transfer within such networks. The guest engineer system that was widely adopted in the Japanese automotive industry following the Second World War is the focus of this study. Significant positive effects of common knowledge shared by the firms involved, a constructive role of individuals as conveyors of information, and increased productivity and human capital gains are found to result from inter-firm network communication in the context of the Japanese automotive industry.
Zwischen Vergemeinschaftung und Anarchie. Zur Konzeption und Wahrnehmung polisübergreifender Beziehungen in klassischer Zeit
Authors: Osmers Maria 
Published: July 2015

Zusammenfassung
Der Artikel fragt zunächst nach Konzepten, die in klassischer Zeit von Außenpolitik existierten. Überlegungen zu diesem Thema sind in den antiken philosophischen Schriften greifbar, wobei Vorstellungen von der Funktionsweise des Oikos und der Polis auf den griechischen Raum übertragen wurden. Ähnliche Kategorien, um polisübergreifende Beziehungen zu beschreiben, griff die politische Rhetorik auf. Bezogen sich antike Autoren jedoch in allgemeinen Abhandlungen auf die Außenpolitik, wurde der Krieg als bestimmendes Element identifiziert. Das theoretische Konzept von Außenpolitik konnte demnach für die Zeitgenossen in der Praxis wenig Wirkung entfalten. Ursachen hierfür waren sowohl die unsteten Verhältnisse des 4. Jahrhunderts als auch die konkrete Konzeption der Außenpolitik, da die Interaktion im griechischen Raum anders funktionierte als in kleineren sozialen Einheiten. Zudem wurden real existierende Mechanismen zur Befriedung von Hellas nur unzureichend in die Konzeption integriert.
Die Gründung Konstantinopels zwischen Sagenkreisen und Zeitzyklen:
Authors: Olbrich Konstantin 
Published: July 2015

Zusammenfassung
Um sich zuspitzenden Dekadenzängsten der römischen Gesellschaft zu begegnen, reaktivierte Kaiser Constantin I. in den Jahren vor der Neugründung Byzantions ein zusammenhängendes Programm von Kulten, die sich während der Krise des 2. punischen Krieges bewährt hatten: Erneut sollten die Gottheiten Mens, Saturn und Kybele das Wohlergehen des krisenerschütterten Staates sicherstellen, wobei sich insbesondere Kybele, in den speziellen Ausprägungen der Mater Palatina sowie der Meter Dindymene, zur Schutzherrin des Neuen Rom weiterentwickelte. In Gestalt der Gottesmutter vom Berg Dindymos, ein dem Argonautenmythos entnommener Typos, diente sie speziell als Garantin der Versöhnung von West- und Ostreich nach dem Bürgerkrieg von 324. Gleichzeitig wurde Kybeles Gatte Saturn als Herr eines neuen Goldenen Zeitalters propagiert, das mit der Gründung Konstantinopels begann. Unter dem Einfluß des Ossius von Cordoba knüpfte es mittelbar an die Epoche der spanischen Era an: das Jahr 38 v. Chr. Auf diese Weise wurde das neue Weltalter unter besondere Auspizien der claudischen Dynastie gestellt, der sich Constantin wohl auch deshalb als zugehörig verstand, um als Abkömmling Kybeles deren Schutz auf die neue Stadt erstreckt zu sehen. Schließlich fungierte Kybele durch ihre enge Verbindung mit Hekate und dem Argonautenmythos als Brücke zu den Lokalmythen Byzantions, die auf die weltbeherrschende und versöhnende Zukunft der Stadt Constantins vorauswiesen.
Archäologie, Geschichte und Münzen
Authors: Wolters Reinhard 
Published: July 2015

ZusammenfassungNur wenige Jahre nach dem Bimillennium der Varuskatastrophe legt Gustav Adolf Lehmann noch einmal einen weit ausgreifenden Überblick zur römischen Germanienpolitik über drei Jahrhunderte vor. Ausgewählte archäologische Funde und Befunde jüngerer Zeit sind nicht nur zentrale Bausteine einer neuen historischen Synthese, sondern konsequent werden die archäologischen Befunde auch für das Verstehen und Beurteilen der schriftlichen Überlieferung nutzbar gemacht. Neben der Würdigung der aufgezeigten Perspektiven und neuen Herangehensweisen wird für einige zentrale und anhaltend strittige Bereiche gezeigt, wie die Vorstellung archäologischer und numismatischer Befunde ihrerseits von historischen, letztlich auf schriftliche Überlieferung zurückgehenden Vorannahmen bestimmt ist.
Carl Friedrich Lehmann-Haupt. Das Leben eines fast vergessenen Althistorikers und Altorientalisten1
Authors: Kellner Angelika 
Published: July 2015

ZusammenfassungDer Aufsatz bietet einen Überblick über das Leben des Althistorikers und Altorientalisten Carl Friedrich Lehmann-Haupt (1861–1938), der aufgrund seiner jüdischen Herkunft im nationalsozialistischen Regime nach seinem Ableben 1938 beinahe in Vergessenheit geraten ist. Neben einer Darstellung seiner internationalen Lehrtätigkeit an den Universitäten in Berlin, Liverpool, Oxford, Greifswald, Istanbul und Innsbruck wird der Versuch unternommen, die Person hinter den Forschungen zu beleuchten. So zeichnete sich Lehmann-Haupt auch durch sein politisches Engagement für das armenische Volk und die deutsche Nation während des Ersten Weltkriegs aus. Neu aufgefundene Briefe geben zudem Auskunft über Lehmann-Haupts fachliche Vernetzung und gewähren einen Einblick in seine wissenschaftliche Betätigung.
Johann Joachim Spalding und der Berliner Gesangbuchstreit (1781)
Authors: van Spankeren Malte 
Published: July 2015

AbstractIn the beginning of the 1780 s the Berliner popular pastor und foremost „Neologe“ Johann Joachim Spalding (1714–1804) was involved into a conflict which was about the implementation of a new hymnbook. Spalding defended this new hymnbook against all critics in his „Predigt von dem, was erbaulich ist“ (1781). The analysis of this conflict can be seen as a contribution to a precise understanding of the controversities in the late enlightenment. Furthermore it shows how Spalding argued against his critics and how he tried to convince his congregation.
To Unite Religion Against All Irreligion. The 1893 World Parliament of Religions
Authors: Molendijk Arie L. 
Published: July 2015

AbstractThe aim of this contribution is to give a comprehensive and readable account of the first World Parliament of Religions held in Chicago in 1893. The Parliament was organised in the context of the Columbian World Exhibition and attracted 150,000 people, according to one of the lenghty reports. Various aspects are addressed: the objectives of the organisers, the character of the various reports of this mega-event, the participation of women (who were among the speakers), the relationship between the Christian organisers and the representatives of the East, the various – opposing – claims about the superiority of specific forms of religion and culture, the tendency to spiritualize religion, and the role of the emerging field of religious studies versus the ‘interfaith’ character of the Parliament. The participants were convinced of the ultimate meaning of ‘religion’ as a force against indulging in consumerism and materialism (which form in this view the core of irreligion).
Un recorrido por categorías y representaciones sobre juventud en las Ciencias Sociales
Authors: Palazzo María Gabriela 
Published: July 2015

Este trabajo propone un recorrido teórico sobre distintas formas de estudiar las juventudes en nuestro tiempo, atendiendo a determinadas categorías y representaciones desde las que se han abordado tales investigaciones. Estas constituyen hechos discursivos relevantes por su incidencia en la construcción del conocimiento tanto académico como del saber de sentido común. A partir de una selección de líneas y autores que proponen formas de comprender la cuestión juvenil desde distintos campos del conocimiento en las Ciencias Sociales, se revisan nociones como las de identidad, generación, cultura, subcultura y cibercultura juveniles. Asimismo, el trabajo indaga en la operatividad de categorías tales como las de tribus urbanas y nativos/inmigrantes digitales en tanto formas de definir a los y las jóvenes en la actualidad según sus prácticas, especialmente en el Ciberespacio. Finalmente, se hace referencia a resultados de mi propia investigación desde la perspectiva de los Estudios del Discurso
Cambios en el documental de naturaleza televisivo en España. De Félix Rodríguez de la Fuente a Frank Cuesta (1974-2011)
Authors: Alberich-Pascual Jordi , Aguirre Salmerón María 
Published: July 2015

El presente artículo presenta los cambios que se han producido en el discurso de los documentales de naturaleza televisivos producidos en España. Para ello, desarrolla el estudio comparativo de una muestra seleccionada de programas correspondientes a las series El Hombre y la Tierra (TVE, 1974) de Félix Rodríguez de la Fuente, y de Frank de la Jungla y La selva en casa (Molinos de Papel, 2010-2011) de Frank Cuesta. El análisis de los resultados permite señalar las transformaciones del género documental desde una paleotelevisión de servicio público, hasta las formas más recientes de neotelevisión privada y comercial.
Comparison of Single Stage and Multistage Permanent Deformation Test for Recycled Asphalt Pavement as a Flexible Pavement Base Layer Material
Authors: Waldenmaier Anthony J. , Abdelrahman Magdy , Attia Mohamed Ibrahim El-Sharkawi 
Published: July 2015

Abstract
Recycled asphalt pavement (RAP) has been shown to be a viable material as an aggregate replacement for flexible pavement base layers. Resilient modulus testing shows the potential of the material to perform comparably to virgin aggregate with moisture content, stress history, fines content, and RAP content shown to be influential testing factors. The resilient modulus test provides a quantifiable comparison between materials based on measureable stiffness, but further research must expand testing to determine deformation characteristics for traffic loadings using permanent deformation testing. This paper presented an analytical summary of testing results of multistage and single stage permanent deformation testing of RAP blended with a typical granular fill material. Multistage repeated triaxial loading was used to assess the development of strain in RAP blends under increasing stress loads. This testing method allowed for the study of strain response and permanent deformation with varied stress applications by simpler and shorter methods than single stage testing and the resilient modulus test. The basis of comparison between material samples and test methods of RAP blends was by (1) the strain, stress, and number of cycles where multistage strain is equivalent to single stage strain, (2) the early deformation during each 5,000-cycle loading stage, and (3) the state of stress and the point of failure. RAP blends were less susceptible to strain, and failed after longer testing and higher stresses than class 5 material. The multistage test method provided a single test to display the short- and long-term strain response at varying stress levels to provide further classification methods for RAP.
Opioid-induced secondary adrenal insufficiency presenting as hypercalcaemia
Authors: Lee Angela S , Twigg Stephen M 
Published: July 2015

SummaryAdrenal insufficiency is a rare cause of hypercalcaemia and should be considered when more common causes such as primary hyperparathyroidism and malignancy are excluded. Opioid therapy as a cause of adrenal insufficiency is a possibly under-recognised endocrinopathy with potentially life-threatening adverse effects. We report on a case of opioid-induced secondary adrenal insufficiency presenting as hypercalcaemia. The patient was a 25-year-old man who developed hypercalcaemia during the recovery stage after a period of critical illness. Systematic investigation of his hypercalcaemia found it to be due to secondary adrenal insufficiency, developing as a consequence of methadone opioid analgesia. Treatment with i.v. saline and subsequent glucocorticoid replacement led to resolution of the hypercalcaemia. The hypoadrenalism resolved when opioids were subsequently weaned and ceased. These two interacting endocrinopathies of opioid-induced adrenal insufficiency and consequent hypercalcaemia highlight the importance of maintaining awareness of the potentially serious adverse clinical outcomes which can occur as a result of opioids, particularly considering that symptoms of hypoadrenalism can overlap with those of concomitant illness. Treatment with hydration and glucocorticoid replacement is effective in promptly resolving the hypercalcaemia due to hypoadrenalism. Hypoadrenalism due to prescribed and recreational opioids may be more common than is currently recognised.Learning pointsOpioid therapy can cause clinically significant secondary adrenal insufficiency, and this may be more common than is currently recognised.Adrenal insufficiency is reversible after discontinuation of the opioid therapy.Hypercalcaemia can occur as a consequence of adrenal insufficiency, and may be the presenting feature.Treatment of hypercalcaemia due to adrenal insufficiency involves i.v. saline and glucocorticoid replacement.
Community Engagement in the Humanities, Arts, and Social Sciences: Academic Dispositions, Institutional Dilemmas
Authors: Dorow Sara , Smith-Acu Nicole 
Published: July 2015

Engaged scholarship is increasingly concerned with how community engagement might be institutionalized in the contemporary university. At the same time, it must be attentive to diverse academic approaches to knowledge and to the forms of engagement associated with them. Attention to this plurality is especially important in the humanities, arts, and social sciences (HASS). Based on a multi-method study conducted in the Faculty of Arts at a large western Canadian research university, this paper maps the demographic positions (gender, rank, and discipline) and scholarly dispositions (stances adopted toward the production of knowledge and the role of the academic) of HASS faculty and contract instructors onto the range of ways they perceive and practice engagement. Against this backdrop, we present a qualitative case study of two pairs of faculty that fleshes out the complexities and possibilities of divergent dispositions and the forms and experiences of engagement with which they are associated. We assert that understanding differentiated starting points to knowledge production among HASS academics is an important pathway to the fuller recognition and flexible institutionalization of engagement in research universities.Â Â