bluuebunny/crossref_metadata_2025_split huggingface dataset:
The development of a rat model to investigate the formation of blast-related post-traumatic heterotopic ossification
Authors: Polfer E. M. , Hope D. N. , Elster E. A. , Qureshi A. T. , Davis T. A. , Golden D. , Potter B. K. , Forsberg J. A. 
Published: March 2015

Currently, there is no animal model in which to evaluate the underlying physiological processes leading to the heterotopic ossification (HO) which forms in most combat-related and blast wounds. We sought to reproduce the ossification that forms under these circumstances in a rat by emulating patterns of injury seen in patients with severe injuries resulting from blasts. We investigated whether exposure to blast overpressure increased the prevalence of HO after transfemoral amputation performed within the zone of injury. We exposed rats to a blast overpressure alone (BOP-CTL), crush injury and femoral fracture followed by amputation through the zone of injury (AMP-CTL) or a combination of these (BOP-AMP). The presence of HO was evaluated using radiographs, micro-CT and histology. HO developed in none of nine BOP-CTL, six of nine AMP-CTL, and in all 20 BOP-AMP rats. Exposure to blast overpressure increased the prevalence of HO. This model may thus be used to elucidate cellular and molecular pathways of HO, the effect of varying intensities of blast overpressure, and to evaluate new means of prophylaxis and treatment of heterotopic ossification. Cite this article: Bone Joint J 2015;97-B:572–6
Chongqing Museums after the Upheaval: Exhibitions in the Wake of the Three Gorges Dam Migrations
Authors: Le Mentec Katiana 
Published: March 2015

Abstract
In the past twenty years, the Chongqing Municipality in China has experienced major social and territorial transformations. Created in 1997 as an autonomous administrative entity, it was partly formed to address the massive migration caused by the building of the Three Gorges Dam. This article explores how museums in the municipality’s cities of Chongqing, Wanzhou and Yunyang were developed after the Dam’s disruptions. Extensive ethnographic fieldwork identified the museum techniques that aimed to cope with the recent changes. Innovations included presentations of the pain suffered by migrants, and the reinvention of regional history based on former migrations and an ancient kingdom elevated to serve as the cradle of Chongqing culture.
Terms of Encounter: The ’85 New Wave and France, Magiciens de la Terre and Chine Demain pour Hier
Authors: Pocock Melanie 
Published: March 2015

Abstract
This article focuses on the encounters and exchanges between French and Chinese artists, art critics and curators from 1985–90 and their impact on the development of two important presentations of the ’85 New Wave movement in France: Magiciens de la Terre (1989) and Chine Demain pour Hier (1990). Drawing on interviews with French and Chinese artists, critics and curators, it argues how the politics of intercultural encounters influenced the curatorial frameworks of both these exhibitions. Such politics ranged from the conditions of artistic exchanges between France and China initiated under French cultural policies to issues of linguistic and cultural translation.
The Art of Diplomacy: The Role of Exhibitions in the Development of Taiwan–China Relations
Authors: McIntyre Sophie 
Published: March 2015

Abstract
In 2009 and 2011, Taiwan’s premier public art museum, the Taipei Fine Arts Museum presented two major solo exhibitions by prominent Chinese artists Cai Guo-Qiang and Ai Weiwei. These exhibitions signified a critical juncture in museological practice in Taiwan and they were closely aligned with the Taiwan government’s mission to develop closer ties with China. This article investigates the role of art in the development of cross-strait relations, including how it is being deployed by governments on both sides as a vehicle for soft power, as well as some of the political agendas that influenced and shaped exhibitions of Chinese art in Taiwan. By exploring issues of representation and reception, this article considers how the local art community is responding to Taiwan’s rapprochement with China, and to the growing visibility of Chinese art in its museums.
International Curatorial Practice and the Problematic De-territorialization of the ‘Identity’ Show: Deconstructing the Third Guangzhou Triennial, Farewell to Post-Colonialism
Authors: Gladston Paul 
Published: March 2015

Abstract
The Third Guangzhou Triennial, Farewell to Post-Colonialism (2008) was intended as a return to a searching deconstructivist critique of the relationship between identity and social inequality. This article seeks to problematize that intended significance by drawing attention to ways in which the position adopted by the curators of the exhibition was rendered critically ineffective as a result of the de-territorializing effects of localized discursive restrictions on public display and discussion. In reconsidering the international ‘identity’ show more generally, attention will be drawn towards the necessity of a renewed deconstructive attention not only to specific instances of cultural dominance, but also relationships between curatorial practices and their particular discursive contexts.
Intergenic Spacer Length Variability in Cultivated, Weedy and Wild Rye Species
Authors: Skuza L. , Filip E. , Szućko I. 
Published: March 2015

Abstract
Non-coding rDNA spacers (IGS) can vary
substantially in size due to differences in the number of
repetitive elements among closely related species. Three
pairs of universal primers were used in this study for the
amplification of non-coding regions of ribosomal (rRNA)
IGS. The amplified IGS products obtained from 19 Secale
accessions, which included both cultivated and noncultivated
rye and which represented three species and
four subspecies of the genus Secale, showed a high level
of polymorphism. The PCR results were characterized by
multiple bands (1-6), different sizes (750bp-3250bp) and
100% polymorphism. Cluster analysis using the neighborjoining
method based on the Dice’s coefficient of genetic
similarity showed a division of the studied species into
two similarity groups. All the studied Secale cereale
ssp. cereale were found to belong to the same similarity
group. The variation in the size of the IGS among the
species which was detected in this study could be due to
dissimilarity between the sequences of their respective
repetitive elements or between their tandem repeat
numbers. The highly interspecific polymorphisms for the
rDNA IGS regions suggested that IGS might be a useful
molecular marker in studies of Secale species.
Proteomic proof that a probiotic elevates
glutathione level in human serum
Authors: Rehema Aune , Kullisaar Tiiu , Seer Kärt , Reinmann Kristen , Zilmer Mihkel , Kilk Kalle 
Published: March 2015

Abstract
Lactobacillus fermentum ME-3 (LfME-3) has been
proven to synthesize and secrete glutathione. A regular
use of the foods fermented by it has shown a favourable
influence on human lipid profiles and several antioxidant
parameters. We administered the LfME-3-fermented kefir
for 14 days to 43 human subjects and evaluated their serum
with MALDI-TOF mass spectrometer at the beginning and
end of the test period. We found an increase of the peak at
m/z 308 (corresponding to glutathione) and a new peak
at m/z 1467.
Novel association of FCGR2A polymorphism with age-related macular degeneration (AMD) and development of a novel CFH real-time genotyping method
Authors: Velissari Aliki , Skalidakis Iosif , Oliveira Samantha C. , Koutsandrea Chryssanthi , Kitsos George , Petersen Michael B. , Kroupis Christos 
Published: March 2015

AbstractAge-related macular degeneration (AMD) is a degenerative ocular disease, which may lead to loss of central vision. In Caucasian populations, a strong correlation has been established with polymorphism Y402H (rs1061170) in the complement factor H gene (DNAs were extracted from blood samples of 120 patients with the severe wet form of AMD and 103 age- and sex-matched controls, all of whom were clinically evaluated. A real-time PCR and melting curve analysis method for Y402H genotyping was developed in the LightCycler platform, after in silico design of appropriate primers and probes. Genotyping for H131R was performed using a real-time PCR method previously described by our group.The novel genotyping method for Y402H in theThe present study confirmed the association between
Preparation of cysteine adducts by regioselective ring-opening reactions of phenyloxirane
Authors: Moulisová Alena , Linhart Igor 
Published: March 2015

Abstract
Regioselective ring-opening reactions of phenyloxirane by protected cysteine are described, which enable the synthesis of pure regioisomeric cysteine adducts required for bioanalytical studies on adducts of protein with styrene. The reaction catalyzed by tris(pentafluorophenyl)borane proceeds regioselectively and stereospecifically to give protected S-(2-hydroxy-1-phenylethyl)cysteine (α-adduct) with the inversion of configuration at the α-carbon. By contrast, when the same reaction is catalyzed by tetraalkylammonium fluorides, S-(2-hydroxy-2-phenylethyl)cysteine (β-adduct) is formed predominantly, and a compete racemization is observed.
Nitrosyl–heme and anion–arene complexes: structure, reactivity and spectroscopy
Authors: Crestoni Maria Elisa , Chiavarino Barbara , Fornarini Simonetta 
Published: March 2015

Abstract
Two topics are selected and illustrated to exemplify (i) a biological and (ii) an organic ionic intermediate. The reactivity behavior of NO adducts with ferric and ferrous hemes has shown remarkable similarities when examined in the gas phase, demonstrating that the largely different NO affinity displayed in solution and in biological media is due to the different coordination environment. In fact, ferrous hemes present a vacant or highly labile axial coordination site, prone to readily bind NO. The vibrational signatures of the NO ligand have also been probed in vacuo for the first time in the nitrosyl complexes deriving from ferrous and ferric hemes under strictly comparable five-coordination at the metal center. Negatively charged σ-adducts, from the association of anions with 1,3,5-trinitrobenzene, an exemplary π-electron-deficient arene, have been probed by IRMPD spectroscopy and found to display variable binding motifs from a strongly covalent σ-adduct (Meisenheimer complex) to a weakly covalent σ-complex, depending on the anion basicity.
Effect of Rotor Diameter on the Thermal Stresses of a Turbine Rotor Model
Authors: Dávalos J. O. , García J. C. , Urquiza G. , Castro-Gómez L. L. , Rodríguez J. A. , De Santiago O. 
Published: March 2015

AbstractThermal stresses in a simplified steam turbine rotor model during a cold startup are analyzed using finite element analysis (FEA). In order to validate the numerical model, an experimental array is developed in which a hollow cylinder is heated with hot air in the external surface. At the thick wall of the cylinder, temperature distribution is measured in real time, while at the same time an algorithm computes thermal stresses. Additional computational fluid dynamics (CFD) calculations are made to obtain magnitudes of velocity and pressure in order to compute convective heat transfer coefficient. The experimental results show good agreement with the FEA computations. To evaluate the effect of rotor diameter size, FEA computations with variation in external and internal diameters are performed. Results show that thermal stresses are proportional to rotor diameter size. Also, zones of higher stress concentration are found in the external and internal surfaces of the rotor.
Effect of Al substitution on Thermoelectric Performance of CuInTe2 compounds
Authors: Hu Chuandeng , Peng Kunling , Wang Guiwen , Guo Lijie , Wang Guoyu , Zhou Xiaoyuan 
Published: March 2015

ABSTRACTThermoelectric CuIn1-xAlxTe2 compounds (x=0, 0.05, 0.1, 0.15, 0.50) have been synthesized by solid state reaction followed by spark plasma sintering. The influence of Al substitution on electrical and thermal transport properties has been investigated in the CuInTe2 compounds. It was found that the Seebeck coefficient and electrical conductivity is reduced by isovalent replacement of In with Al. Our first principle calculation indicates Al substitution leads to the widen band gap, the reduction in the number of degeneracy of valence band and the effective mass. Furthermore, a large reduction in thermal conductivity is achieved through the enhanced phonon scattering via point defect as well as the nano-sized particles observed between grain boundaries and on the grain surface. In spite of the reduced charge transport properties, an improved figure-of- merit ZT is achieved, reaching 0.8 at 800 K, 33% higher in comparison to the pure CuInTe2 compound.
Key Phenomena Governing HLW Glass Behavior in the French Deep Geological Disposal
Authors: Schumacher Stéphan , Martin Christelle , Linard Yannick , Angeli Frédéric , Neff Delphine , Abdelouas Abdesselam , Crozes Xavier 
Published: March 2015

ABSTRACTAccording to the Planning Act of 28th June 2006, Andra is in charge of ensuring the sustainable management of all radioactive waste generated in France, especially the high-level and long-lived vitrified waste produced from spent fuel recycling.Since 2006, all the studies and research related to the components of HLW cells have been incorporated into a broader R&D program which aims at characterizing and modeling (i) the glass matrix dissolution, (ii) the corrosion of the overpack and the lining, and (iii) the claystone evolution in the near field, considering all the interactions between these surrounding materials. This program, coordinated by Andra, has involved up to eighteen laboratories.After closure of disposal cells and overpack failure, glass alteration is expected to begin in partially saturated conditions due to hydrogen production resulting from carbon steel corrosion in anoxic conditions. Therefore, the glass should at least partially be hydrated by water vapor during thousands of years until complete saturation. A part of the studies aimed to determine the glass behavior in such conditions, the influence of the main parameters (temperature, relative humidity) and consequences of vapor hydration on subsequent radionuclides release by water leaching.In addition, the major part of the work focused on the influence of the environment on glass alteration. The effect of clay pore water on glass alteration rates (initial rate, rate drop and residual rate) was determined and particularly that of pH and magnesium. The nature of steel corrosion products and their interactions with glass alteration were also investigated. All these studies relied on experiments in surface laboratories, in Andra’s underground laboratory, together with natural or archeological analogs and modeling studies.
Monitoring the Electrochemical Response of Chloride Sensors Embedded in Cement Paste
Authors: Pargar F. , Koleva D.A. , Koenders E.A.B. , van Breugel K. 
Published: March 2015

ABSTRACTThis work presents the electrochemical behavior of Ag/AgCl electrodes (chloride sensors) in cement paste environment, monitored over a period of 180 days via open circuit potential (OCP) readings and electrochemical impedance spectroscopy (EIS). The EIS response indicates modification of the sensors’ morphology, in particular alteration of the AgCl layers, as a result of continuous chloride penetration into the bulk matrix towards the vicinity of the sensor/cement paste interface. A gradual shift to more cathodic OCP values and stabilization at approximately -1mVSCE to 2mVSCE was observed at the end of the test, reflecting chloride content of 820mM to 930mM in the pore solution surrounding the sensors, which differs 5-10% from the chloride concentration in the external solution. The water soluble chloride content in the cement pate, as destructively measured wet chemically by Volhard method and photometry, was in the range of 1100mM - 1300mM i.e. about 30-50% more than the chloride concentration in the external solution. This difference of maximum 50% in the recorded chloride levels is attributed to the fact that the sensors “read” the average amount of free chloride at the interface sensor/cement paste, while the destructively measured water soluble chloride reflects the average free (with possible contribution of physically bound chloride) in the total volume of analyzed cement paste. It can be concluded that for the conditions of this experiment, more reliable free chloride content is measured via the sensors’ readings. Hence, if chloride thresholds for corrosion initiation are to be determined, the sensors’ readings will be more representative and accurate if compared to destructive water soluble chloride determination.
The Effects of Internal Audit Report Type and Reporting Relationship on Internal Auditors' Risk Judgments
Authors: Boyle Douglas M. , DeZoort F. Todd , Hermanson Dana R. 
Published: March 2015

SYNOPSIS
The governance literature (e.g., Archambeault, DeZoort, and Holt 2008) highlights the lack of internal audit information available to external stakeholders and discusses the need for a publicly available internal audit report (IAR) to describe the function and/or provide assurance. We study the effects of IAR type (i.e., descriptive IAR, assurance IAR) and internal audit reporting relationship (i.e., primarily to management or primarily to the audit committee) on internal auditors' judgments. Specifically, 108 experienced internal auditors provided fraud risk and control risk assessments in an experiment where IAR type and reporting relationship were manipulated randomly between subjects. Fraud risk assessments are higher (more conservative) when internal auditors provide assurance in an IAR or when they report primarily to the audit committee. A significant interaction indicates that internal auditors provide higher control risk assessments when they provide assurance in an IAR and report primarily to the audit committee. Providing descriptive information in an IAR to external stakeholders does not significantly affect internal auditors' fraud risk or control risk assessments. Supplemental results indicate moderate and varied support among internal auditors for the issuance of a descriptive IAR to external stakeholders, but significantly less support for the issuance of an assurance IAR. The results, in combination with Holt and DeZoort's (2009) evidence regarding the effect of descriptive IARs on investors' judgments, suggest the need for discussions of the value of IARs in practice.
Neuromuscular blocking effects of vecuronium in dogs with autosomal-recessive centronuclear myopathy
Authors: Martin-Flores Manuel , Paré Monique D. , Tomak Emily A. , Corn Morgan L. , Campoy Luis 
Published: March 2015

Abstract
OBJECTIVE To evaluate the potency of vecuronium and duration of vecuronium-induced neuromuscular blockade in dogs with centronuclear myopathy (CNM).
ANIMALS 6 Labrador Retrievers with autosomal-recessive CNM and 5 age- and weight-matched control dogs.
PROCEDURES Dogs were anesthetized on 2 occasions (1-week interval) with propofol, dexmedetomidine, and isoflurane. Neuromuscular function was monitored with acceleromyography and train-of-four (TOF) stimulation. In an initial experiment, potency of vecuronium was evaluated by a cumulative-dose method, where 2 submaximal doses of vecuronium (10 μg/kg each) were administered IV sequentially. For the TOF's first twitch (T1), baseline twitch amplitude and maximal posttreatment depression of twitch amplitude were measured. In the second experiment, dogs received vecuronium (50 μg/kg, IV) and the time of spontaneous recovery to a TOF ratio (ie, amplitude of TOF's fourth twitch divided by amplitude of T1) ≥ 0.9 and recovery index (interval between return of T1 amplitude to 25% and 75% of baseline) were measured.
RESULTS Depression of T1 after each submaximal dose of vecuronium was not different between groups. Median time to a TOF ratio ≥ 0.9 was 76.7 minutes (interquartile range [IQR; 25th to 75th percentile], 66.7 to 99.4 minutes) for dogs with CNM and 75.0 minutes (IQR, 47.8 to 96.5 minutes) for controls. Median recovery index was 18.0 minutes (IQR, 9.7 to 23.5 minutes) for dogs with CNM and 20.2 minutes (IQR, 8 to 25.1 minutes) for controls.
CONCLUSIONS AND CLINICAL RELEVANCE For the study dogs, neither potency nor duration of vecuronium-induced neuromuscular blockade was altered by CNM. Vecuronium can be used to induce neuromuscular blockade in dogs with autosomal-recessive CNM.
Renal, gastrointestinal, and hemostatic effects of oral administration of meloxicam to Hispaniolan Amazon parrots (Amazona ventralis)
Authors: Dijkstra Bas , Guzman David Sanchez-Migallon , Gustavsen Kate , Owens Sean D. , Hass Carlyle , Kass Philip H. , Paul-Murphy Joanne R. 
Published: March 2015

Abstract
OBJECTIVE To investigate renal, gastrointestinal, and hemostatic effects associated with oral administration of multiple doses of meloxicam to healthy Hispaniolan Amazon parrots (Amazona ventralis).
ANIMALS 12 Hispaniolan Amazon parrots.
PROCEDURES Birds were assigned to receive meloxicam oral suspension (1.6 mg/kg, PO, q 12 h) and 2.5 mL of tap water inserted into the crop by use of a gavage tube (n = 8) or the equivalent volume of tap water only (control group; 4) for 15 days. Urine and feces were collected 2 hours after treatment administration each day. Feces were evaluated for occult blood. Results of a CBC and serum biochemical analysis and measured N-acetyl-β-d-glucosaminidase (NAG) activity and whole blood clotting time were evaluated before, during, and after completion of treatments. Results of urinalysis and measured urine NAG activity were also evaluated.
RESULTS Birds treated with meloxicam had a significant increase in number of WBCs and decrease in PCV from before to after treatment. The PCV also decreased significantly, compared with results for the control group; however, WBC count and PCV for all birds remained within reference ranges throughout the study. One parrot treated with meloxicam had a single high value for urine NAG activity.
CONCLUSIONS AND CLINICAL RELEVANCE Meloxicam administered orally at the dosage used in this study caused no apparent negative changes in several renal, gastrointestinal, or hemostatic variables in healthy Hispaniolan Amazon parrots. Additional studies to evaluate adverse effects of NSAIDs in birds will be needed.