bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ein,Nesthocker', Prokne und andere Schwalben: Martial 5, 67
Authors: Schmitz Christine 
Published: March 2015

Abstract
Epigram 5.67 derives its point from Martial's critical and creative way of dealing with the mythical tradition. After he has described from the swallows' perspective an incident that occurred in the avian world, in the last distich the point of view undergoes a surprising shift from the victim to the agent. This is effected by a smooth transition from the swallow that has been cruelly torn to bits by its own kind to the mythical Procne, who tore her son to bits and suffered the punishment of being changed into a swallow. The aetiology that forms the concluding point of the epigram shows the incident in a new light. The nature of swallows is marked once and for all by Procne's behavior: as she once tore Itys to pieces, so the swallows of our epigram behave; indeed, at the very beginning they are pointedly designated as Attbides. The narrator's concluding comment that the guilty mother ought to have been torn to bits immediately after her impious act is an attempt, albeit a vain one, to correct the myth.
A critical review on heat transfer in trickle bed reactors
Authors: Taulamet María J. , Mariani Néstor J. , Barreto Guillermo F. , Martínez Osvaldo M. 
Published: March 2015

AbstractA critical review of the available information about heat transfer between a packed bed with cocurrent downflow of gas and liquid and an external medium was undertaken. Several aspects such as experimental set-ups and methods employed to study heat transfer in trickle bed reactors, models used to interpret experimental data, and literature correlations of heat transfer parameters are addressed. From the analysis of the available experimental information, a refined database has been built, which allows comparing the performance of the existing correlations for the parameters of the extensively employed two-dimensional pseudohomogeneous plug flow model (i.e., effective radial thermal conductivity and wall heat transfer coefficient). In addition, new correlations for effective thermal conductivity have been developed. Identification of gaps in the current knowledge and recommendations for future works are summarized.
Structural changes of synthetic paulingite (Na,H-ECR-18) upon dehydration and CO2 adsorption
Authors: Greenaway Alex G. , Shin Jiho , Cox Paul A. , Shiko Elenica , Thompson Stephen P. , Brandani Stefano , Hong Suk Bong , Wright Paul A. 
Published: March 2015

Abstract
The structure of dehydrated calcined ECR-18, synthetic paulingite, topology type PAU, unit cell composition Na132H28Si512Al160O1344, has been determined by Rietveld refinement against synchrotron X-ray powder diffraction data. Upon dehydration the symmetry of Na,H-ECR-18 changes from

I
m

3
¯

m

$Im\bar 3m$

to

I

4
¯

3
m
,

$I\bar 43m,$

with a corresponding decrease of cubic unit cell a parameter from 34.89412(1) Å to 33.3488(3) Å. This occurs as the framework distorts to afford closer coordination of Na+ cations by framework O atoms in 8-ring window sites of the seven cage types present. Na+ cations in 8R sites block the access of N2 molecules to the internal pore space at 77 K but CO2 adsorption at 308 K is observed, and is postulated to occur via a ‘trapdoor’ mechanism. In situ PXRD during CO2 adsorption at pressures up to 10 bar show reversible broadening of diffraction peaks that is attributed to local crystallographic strain.
A novel biomarker for anti-androgenic activity in placenta reveals risks of urogenital malformations
Authors: Arrebola Juan P , Molina-Molina José M , Fernández Mariana F , Sáenz Jose M , Amaya Esperanza , Indiveri Paolo , Hill Elizabeth M , Scholze Martin , Orton Frances , Kortenkamp Andreas , Olea Nicolás 
Published: March 2015

It has been hypothesized that the rise in male reproductive disorders over recent decades may at least be partially attributable to environmental factors, including chemical exposures, but observed associations with single chemicals were rather weak. The aim of this case–control study was to explore the relationship between exposure to mixtures of (anti-)androgenic chemicals during pregnancy and the risk of cryptorchidism and/or hypospadias in offspring, using the total effective xenobiotic burden of anti-androgens (TEXB-AA) as a biomarker. A subsample of 29 cases (16 of cryptorchidism, 12 of hypospadias, and one of both disorders) and 60 healthy controls was nested in a cohort of male newborns recruited between October 2000 and July 2002. The (anti-)androgenic activity of placenta samples collected at delivery was assessed using TEXB-AA biomarker, combined with a bioassay-directed fractionation protocol that separated endogenous hormones from most (anti-)androgenic chemicals by normal-phase HPLC. The bioassay measures the androgen-induced luciferase activity and the inhibition of this pathway by (anti-)androgens. First, we collected 27 HPLC fractions in each placenta extract, which were all tested in the bioassay. The multivariable statistical analyses indicated a statistically significant positive dose–response association between the potent anti-androgenic activity of the HPLC fraction collected during minutes 1–2 (F2) and the risk of malformations (odds ratio: 2.33, 95% CI: 1.04–5.23). This study represents a novel approach for the estimation of combined effects of the total anti-androgenic load and the associations suggest an effect of environmental pollutants on the development of fetal reproductive tract.Free Spanish abstract: A Spanish translation of this abstract is freely available athttp://www.reproduction-online.org/content/149/6/605/suppl/DC1.
The expanding world of hybrid perovskites: materials properties and emerging applications
Authors: Brittman Sarah , Adhyaksa Gede Widia Pratama , Garnett Erik Christian 
Published: March 2015

AbstractHybrid inorganic–organic perovskites have emerged over the last 5 years as a promising class of materials for optoelectronic applications. Most notably, their solar cells have achieved power conversion efficiencies above 20% in an unprecedented timeframe; however, many fundamental questions still remain about these materials. This Prospective Article reviews the procedures used to deposit hybrid perovskites and describes the resulting crystallographic and morphological structures. It further details the electrical and optical properties of perovskites and then concludes by highlighting a number of potential applications and the materials challenges that must be overcome before they can be realized.
New Materials Optimization Process in Tomato
Authors: Marín Vaca Luz E. , Villegas Torres Oscar G. , Luna Lugo Sergio , Aguilar Cortes Miguel , Lara Ruiz Nadia , Domínguez Patiño Martha Lilia 
Published: March 2015

ABSTRACTThe protected agriculture has gained great importance worldwide in the past 10 years. For example in the case of production in greenhouse conditions, that records an annual growth of 20%.An important aspect greenhouse production is the medium used for growth of the plant, which may be an organic or inorganic substrate.One of the advantages of the use of regional substrates is the availability and lower cost, and further organic in gives the tendency to manage sustainable production systems.The organic substrates alone or in mixtures improve conditions for plant growth in terms of physical, chemical and biological as a perspective.A wide variety of materials that can be used as agricultural substrates, but there are criteria to be considered for its election as: plant requirements, conforming as possible to the ideal characteristics of a substrate and effect on the environment.Overall, we can summarize that a substrate for growing plants is any material that can provide attachment, oxygen and enough water for optimal development of the same, or in nutrient case requirements can be covered with a single material or combination with others.In this paper the tomato crop is presented comparing two production systems to determine the yield and fruit quality under plastic cover, high densities of drip irrigation and using the tezontle as substrate, as this provides good drainage, almost no contribution nutrients and slightly neutral PH. And also allows us to transplant to a larger pot without disturbing the root and provides the necessary aeration.
Ecosystem health towards sustainability
Authors: Lu Yonglong , Wang Ruoshi , Zhang Yueqing , Su Hongqiao , Wang Pei , Jenkins Alan , Ferrier Rober C. , Bailey Mark , Squire Geoff 
Published: March 2015

Abstract
Ecosystems are becoming damaged or degraded as a result of stresses especially associated with human activities. A healthy ecosystem is essential to provide the services that humans and the natural environment require and has tremendous social and economic value. Exploration of the definition of ecosystem health includes what constitutes health and what it means to be healthy. To evaluate ecosystem health, it is necessary to quantify ecosystem conditions using a variety of indicators. In this paper, the main principles and criteria for indicator selection, classification of indicators for different kinds of ecosystems, the most appropriate indicators for measuring ecosystem sustainability, and various methods and models for the assessment of ecosystem health are presented. Drivers, sustainability, and resilience are considered to be critical factors for ecosystem health and its assessment. Effective integration of ecological understanding with socioeconomic, biophysical, biogeochemical, and public‐policy dimensions is still the primary challenge in this field, and devising workable strategies to achieve and maintain ecosystem health is a key future challenge.
Global methane and nitrous oxide emissions from terrestrial ecosystems due to multiple environmental changes
Authors: Tian Hanqin , Chen Guangsheng , Lu Chaoqun , Xu Xiaofeng , Ren Wei , Zhang Bowen , Banger Kamaljit , Tao Bo , Pan Shufen , Liu Mingliang , Zhang Chi , Bruhwiler Lori , Wofsy Steven 
Published: March 2015

Abstract

Greenhouse gas (GHG)‐induced climate change is among the most pressing sustainability challenges facing humanity today, posing serious risks for ecosystem health. Methane (CH
4
) and nitrous oxide (N
2
O) are the two most important GHGs after carbon dioxide (CO
2
), but their regional and global budgets are not well known. In this study, we applied a process‐based coupled biogeochemical model to concurrently estimate the magnitude and spatial and temporal patterns of CH
4
and N
2
O fluxes as driven by multiple environmental changes, including climate variability, rising atmospheric CO
2
, increasing nitrogen deposition, tropospheric ozone pollution, land use change, and nitrogen fertilizer use. The estimated CH
4
and N
2
O emissions from global land ecosystems during 1981–2010 were 144.39 ± 12.90 Tg C/yr (mean ± 2 SE; 1 Tg = 1012 g) and 12.52 ± 0.74 Tg N/yr, respectively. Our simulations indicated a significant (
P
< 0.01) annually increasing trend for CH
4
(0.43 ± 0.06 Tg C/yr) and N
2
O (0.14 ± 0.02 Tg N/yr) in the study period. CH
4
and N
2
O emissions increased significantly in most climatic zones and continents, especially in the tropical regions and Asia. The most rapid increase in CH
4
emission was found in natural wetlands and rice fields due to increased rice cultivation area and climate warming. N
2
O emission increased substantially in all the biome types and the largest increase occurred in upland crops due to increasing air temperature and nitrogen fertilizer use. Clearly, the three major GHGs (CH
4
, N
2
O, and CO
2
) should be simultaneously considered when evaluating if a policy is effective to mitigate climate change.
Evaluation of an Online Campaign for Promoting Help-Seeking Attitudes for Depression Using a Facebook Advertisement: An Online Randomized Controlled Experiment
Authors: Hui Alison , Wong Paul Wai-Ching , Fu King-Wa 
Published: March 2015

Background
A depression-awareness campaign delivered through the Internet has been recommended as a public health approach that would enhance mental health literacy and encourage help-seeking attitudes. However, the outcomes of such a campaign remain understudied.

Objective
The main aim of this study was to evaluate the effectiveness of an online depression awareness campaign, which was informed by the theory of planned behavior, to encourage help-seeking attitudes for depression and to enhance mental health literacy in Hong Kong. The second aim was to examine click-through behaviors by varying the affective facial expressions of people in the Facebook advertisements.

Methods
Potential participants were recruited through Facebook advertisements, using either a happy or sad face illustration. Volunteer participants registered for the study by clicking on the advertisement and were invited to leave their personal email addresses to receive educational content about depression. The participants were randomly assigned into two groups (campaign or control), and over a four consecutive week period, received either the campaign material or official information developed by the Hospital Authority in Hong Kong. Pretests and posttests were conducted before and after the campaign to measure the differences in help-seeking attitudes and mental health literacy among the campaign and control groups.

Results
Of the 199 participants that registered and completed the pretest, 116 (55 campaign and 62 control) completed the campaign and the posttest. At the posttest, we found no significant changes in help-seeking attitudes between the campaign and control groups, but the campaign group participants demonstrated a statistically significant improvement in mental health literacy (P=.031) and a higher willingness to access additional information (P<.001) than the control group. Moreover, the happy face Facebook advertisement attracted more click-throughs by users into the website than did the sad face advertisement (P=.03).

Conclusions
The present study provides evidence that an online campaign can enhance people’s mental health literacy. It also demonstrates the practicality and effectiveness of an online depression awareness campaign using a Facebook-based recruitment strategy and distribution of educational materials through emails. It is important for future studies to take advantage of the popularity of online social media and conduct evaluative research on mental health promotion campaigns.
In-Transit Metastasis from Primary Cutaneous Squamous Cell Carcinoma in a Nonimmunosuppressed Patient
Authors: Kocatüurk Emek , Ülkümen Pelin Kuteyla , Kizitaç Utkan , Yüksel Tülin , Kunter Ayşle Seza , Erhan Selma Şlengiz 
Published: March 2015

Background In-transit metastases are dermal and subcutanous metastatic foci located between the tumor and the closest regional lymph node. Although in-transit metastasis has been commonly described for malignant melanoma, there have been some reports of in-transit metastases arising from primary cutaneous malignancies. The risk of development of in-transit metastases is higher in patients with high-risk squamous cell carcinoma. Case Report We present a case of in-transit metastasis in a nonimmunosuppressed patient with a primary cutaneous squamous cell carcinoma.
Acitretin-Induced Hepatitis: When to Monitor Cholestatic Enzymes
Authors: Sauder Maxwell B. , Cheung Loretta , Beecker Jennifer 
Published: March 2015

Importance Acitretin is a systemic retinoid that is used in dermatology for a variety of conditions. A well-recognized potential adverse event from acitretin is elevated transaminases, indicating acute hepatocyte damage. Less well known is the possible cholestatic injury that can occur, signaled by elevated γ-glutamyltransferase (GGT) and alkaline phosphatase (ALP). Observations Our patient presented with an acute acitretin-induced hepatitis with a mixed pattern of elevated transaminases as well as GGT and ALP. A literature review demonstrated that most cases of acitretin-induced hepatitis, outside clinical trials, describe patients with a similar mixed hepatitis pattern. Conclusions This is the first literature review on acitretin-induced hepatitis. Although acitretin-induced hepatoxicity is rare, the seemingly unusual presentation of a mixed pattern of hepatocyte injury and cholestasis may be more common than previously thought. The findings should encourage clinicians not only to monitor transaminases but also to consider measuring cholestatic enzymes (ALP/GGT) in patients with transaminase abnormalities.
Pyoderma Gangrenosum among Patients with Inflammatory Bowel Disease: A Descriptive Cohort Study
Authors: Weizman Adam V. , Huang Brian , Targan Stephan , Dubinsky Marla , Fleshner Phillip , Kaur Manreet , Ippoliti Andrew , Panikkath Deepa , Vasiliauskas Eric , Shih David , Mcgovern Dermot P.B. , Melmed Gil Y. 
Published: March 2015

Background Pyoderma gangrenosum (PG) is a severe extraintestinal manifestation of inflammatory bowel disease (IBD). Objective To better characterize PG features and management among an IBD cohort. Methods Subjects with PG were identified using a large database at a tertiary center. Patient demographics and clinical characteristics were summarized using descriptive statistics. Results Eighty patients with an episode(s) of PG were identified, yielding an overall prevalence of 1.9%. Overall, 93% of patients with PG had some degree of colonic inflammation. Thirty-one (39%) patients required hospitalization for PG. Underlying bowel disease was active at the time of PG episode(s) in 52 (65%) patients. The PG location was variable, with the lower extremity being the most common. Most patients (71.3%) required multiple therapies to achieve PG healing. Conclusions We describe one of the largest case series of PG among patients with IBD. The variety of treatment strategies used highlights the lack of clear guidelines in managing this complex group of patients.
Tinea Cruris and Tinea Corporis Masquerading as Tinea Indecisiva: Case Report and Review of the Literature
Authors: Sonthalia Sidharth , Singal Archana , Das Shukla 
Published: March 2015

Background Tinea indecisiva is characterized by concentric scaly rings simulating tinea imbricata but caused by dermatophytes other than Trichophyton concentricum. Objective Tinea indecisiva has been rarely reported. We report a unique case and review of the previously reported cases, pathogenesis, and management. Methods An adult Indian man developed extensive tinea cruris and tinea corporis with concentric rings of scaly lesions over the groin, buttocks, and thighs following the use of oral corticosteroids and antifungal-steroid cream for 3 months. Mycologic and immunologic studies were performed for diagnosis. Results Diagnosis of tinea indecisiva was confirmed on the appearance of “ring-within-a-ring”; lesions clinically and isolation of Trichophyton mentagrophytes var. interdigitale as the etiologic agent on mycologic testing. Intradermal testing with Trichophyton extract showed fluctuating hypersensitivity responses. Four-week treatment with daily oral terbinafine resulted in complete resolution. Conclusion Tinea indecisiva should be considered in a patient with tinea imbricata-like lesions with local immunosuppression caused by a non-concentricum dermatophyte.
Evaluation of the Efficacy and Safety of Topical Imiquimod 5% for Plaque-Type Morphea: A Multicenter, Prospective, Vehicle-Controlled Trial
Authors: Dytoc Marlene , Wat Heidi , Cheung-Lee Melody , Sawyer Douglas , Ackerman Thomas , Fiorillo Loretta 
Published: March 2015

Background There is currently a lack of evidence-based therapies that are safe and effective for plaque-type morphea. We aimed to evaluate the therapeutic potential and safety profile of imiquimod 5% cream in plaque-type morphea. Methods We enrolled 25 adult patients from two Canadian centers with histologically confirmed plaque-type morphea. Imiquimod 5% was applied to a representative plaque, and vehicle was applied to a control plaque for 9 months. Treatment efficacy was assessed with the Dyspigmentation, Induration, Erythema, and Telangiectasias (DIET) score, histology, and ultrasound evaluation. Results and Conclusions Twenty-two patients completed the entire length of the study. Imiquimod 5% was superior to vehicle in reducing DIET scores at 3, 6, 9, and 12 months ( p < .05). Induration demonstrated the greatest response. Histologic evaluation showed significant improvement or resolution of disease. However, no ultrasonographic differences were found in dermal and hypodermal thicknesses between the treatment and vehicle groups ( p > .05). Adverse effects were minimal and well tolerated.
Low Glutathione Peroxidase Activity Levels in Patients with Vitiligo
Authors: Zedan Hatem , Abdel-Motaleb Amira Ali , Kassem Nahed Mahmoud Ali , Hafeez Heba Ahmed Abdel , Hussein Mahmoud Rezk Abdelwhahed 
Published: March 2015

Background Vitiligo is an idiopathic skin disease characterized by white areas on the skin due to loss of the functional melanocytes, with possible involvement of oxidative stress. Glutathione peroxidase (GPx) is an antioxidant enzyme that protects cells against oxidative damage. Aim To examine serum GPx levels in patients with vitiligo and to relate the findings to the clinical features. Patients and Methods The study group included 60 patients with vitiligo and 30 matching healthy controls. GPx activity was evaluated using enzyme-linked immunosorbent assay. Results We found a significant decrease in serum GPx activity level in the patients with vitiligo compared to the healthy controls (0.29 ± 0.14 versus 0.47 ± 0.13, p < .001). The levels were significantly low in skin phenotypes III and IV ( p < .001). Higher levels were also observed with increasing age (≥ 14 years), prolonged disease duration (≥ 3 years), and generalized and extensive vitiligo (<50%). However, these variations were statistically insignificant. Conclusions Low levels of serum GPx activity, indicative of a disturbed oxidant-antioxidant system, may contribute to the development of vitiligo.
Skin Necrosis from Intra-articular Hyaluronic Acid Injection
Authors: Kim Whan B. , Alhusayen Raed O. 
Published: March 2015

Background Tissue necrosis is a rare yet potentially serious complication of intra-articular (IA) hyaluronic acid (HA) injections for treatment of knee osteoarthritis. Objective To report a case of a patient with cutaneous necrosis after IA HA injection for treatment of knee osteoarthritis, presenting as a livedoid violaceous patch on the right knee. Method We report a case of cutaneous necrosis as a rare complication of IA HA injection for treatment of knee osteoarthritis. A literature review was undertaken of similar cases. Results Use of HA IA injections in the treatment of osteoarthritis can result in similar skin necrosis at uncommon anatomic locations corresponding to the site of HA injection. Conclusion Although tissue necrosis is a rare complication, physicians need to be aware of this possibility as a complication of HA IA injections in the treatment of osteoarthritis and should be mindful of potential treatment options to manage this adverse event.