bluuebunny/crossref_metadata_2025_split huggingface dataset:
Influence of soil‐structure interaction on the behavior of the tower‐foundation system of a horizontal‐axis wind turbine
Authors: Medeiros Iálysson da Silva , Bello Maria Isabela Marques da Cunha Vieira , de Lima Douglas Mateus 
Published: July 2024

AbstractThe ongoing advancement of wind turbines, aiming for taller towers to harness more intense winds, poses substantial structural challenges. Soil‐structure interaction (SSI) assumes fundamental importance, necessitating precise analysis, and mathematical modeling. This study focuses on examining how SSI influences horizontal‐axis wind turbine tower‐foundation systems. Six numerical models, varying from simplified to more complex representations, are created using the finite element method (FEM) in ANSYS software. The analysis reveals significant sensitivity to support conditions, particularly elastic supports, causing the greatest displacement at the tower's top (1.899 m), highlighting the substantial influence of SSI and second‐order effects. Incorporating SSI and second‐order effects results in a 30.11% increase in von Mises stress at the base flange (73.4 MPa), compared to models excluding these factors. Stress variation along the tower height notably increases with second‐order effects; however, the structure maintains a 13.32% safety margin relative to steel load‐bearing capacity. Foundation analyses indicate stresses exceeding concrete's allowable stress by 24.3%, underscoring the need for foundation optimization. These results stress the importance of considering SSI and geometric nonlinearity for wind turbine development. The lack of comparable studies in literature underscores the significance of this research in advancing the field's knowledge.
Logistics customer service and customer satisfaction: Importance‐based segments for motor carriers
Authors: Garver Michael S. , Williams Zachary 
Published: July 2024

AbstractThe current research presents a middle‐range theorization of logistics customer service attributes predicting overall customer satisfaction for motor carriers. Latent class regression (LCR) analysis was employed to identify importance‐based segments by examining the relationships between logistics customer service attributes and overall satisfaction as measured by the American Customer Satisfaction Index. LCR analysis identified three importance‐based segments, including a segment focused on basic logistics services, a segment focused on sustainability, and a segment focused on security. Correlated components regression analysis was employed to refine the models of each segment to better understand what logistic customer service attributes were most important to each segment. Following an abductive reasoning process, these research results are compared with the theory of strategic purity.
Synthesis and Characterization of NHC Stabilized Bis(phenylsulfanyl)stannylene
Authors: Mammadova Aynura , Bruhn Clemens , Pietschnig Rudolf 
Published: July 2024

AbstractReaction of two equivalents of ((CH3)3Si)2C(C6H5)SLi ⋅ 3THF with SnCl2⋅IDipp(IDipp=1,3‐bis(2,6‐diisopropylphenyl)imidazol‐2‐ylidene) led to fragmentation of the organolithium component and gave IDipp⋅Sn(SPh)2, compound 3. The latter compound has been further prepared from Ph‐SSi(CH3)3 whereas disproportionation of the Sn(II) species was observed when starting from Ph‐SLi. The stannylene adduct 3 has been characterized spectroscopically and its structure was explored with single crystal X‐ray diffraction (SCXRD). The carbene donor in 3 can be displaced by chloride, upon formal HCl addition, giving rise to the ionic stannylene adduct 4 [IDippH]+[SnCl(SPh)2]−, the structure of which was investigated with SCXRD as well.
Dose prescription for stereotactic body radiotherapy: general and organ-specific consensus statement from the DEGRO/DGMP Working Group Stereotactic Radiotherapy and Radiosurgery
Authors: Brunner Thomas B. , Boda-Heggemann Judit , Bürgy Daniel , Corradini Stefanie , Dieckmann Ute Karin , Gawish Ahmed , Gerum Sabine , Gkika Eleni , Grohmann Maximilian , Hörner-Rieber Juliane , Kirste Simon , Klement Rainer J. , Moustakis Christos , Nestle Ursula , Niyazi Maximilian , Rühle Alexander , Lang Stephanie-Tanadini , Winkler Peter , Zurl Brigitte , Wittig-Sauerwein Andrea , Blanck Oliver 
Published: July 2024

AbstractPurpose and objectiveTo develop expert consensus statements on multiparametric dose prescriptions for stereotactic body radiotherapy (SBRT) aligning with ICRU report 91. These statements serve as a foundational step towards harmonizing current SBRT practices and refining dose prescription and documentation requirements for clinical trial designs.Materials and methodsBased on the results of a literature review by the working group, a two-tier Delphi consensus process was conducted among 24 physicians and physics experts from three European countries. The degree of consensus was predefined for overarching (OA) and organ-specific (OS) statements (≥ 80%, 60–79%, < 60% for high, intermediate, and poor consensus, respectively). Post-first round statements were refined in a live discussion for the second round of the Delphi process.ResultsExperts consented on a total of 14 OA and 17 OS statements regarding SBRT of primary and secondary lung, liver, pancreatic, adrenal, and kidney tumors regarding dose prescription, target coverage, and organ at risk dose limitations. Degree of consent was ≥ 80% in 79% and 41% of OA and OS statements, respectively, with higher consensus for lung compared to the upper abdomen. In round 2, the degree of consent was ≥ 80 to 100% for OA and 88% in OS statements. No consensus was reached for dose escalation to liver metastases after chemotherapy (47%) or single-fraction SBRT for kidney primaries (13%). In round 2, no statement had 60–79% consensus.ConclusionIn 29 of 31 statements a high consensus was achieved after a two-tier Delphi process and one statement (kidney) was clearly refused. The Delphi process was able to achieve a high degree of consensus for SBRT dose prescription. In summary, clear recommendations for both OA and OS could be defined. This contributes significantly to harmonization of SBRT practice and facilitates dose prescription and reporting in clinical trials investigating SBRT.
Rare case of myelodysplastic syndrome with excess blasts 2 developing after adjuvant chemoradiotherapy for triple-negative breast cancer in a patient with Bloom syndrome
Authors: Gürbüz Ali Fuat , Eryılmaz Melek Karakurt , Yıldız Oğuzhan , Kılınç Fahriye , Araz Murat , Artaç Mehmet 
Published: July 2024

Abstract
Introduction
Bloom syndrome (BS) is a rare autosomal recessive disorder caused by a loss-of-function mutation in the BLM gene encoding an RecQ helicase involved in DNA repair and maintenance of chromosomal stability. In patients with BS, significant sensitivity to both DNA-damaging chemotherapy (CT) and ionizing radiation complicates the management of neoplasms by exacerbating comorbidities and predisposing to toxicities and poor outcomes.

Case report
A 30-year-old female patient diagnosed with BS who presented with early-stage triple-negative breast cancer was treated with four cycles of doxorubicin (60 mg/m2) and cyclophosphamide (600 mg/m2) followed by weekly paclitaxel (80 mg/m2) for 12 weeks as the chemotherapy protocol and a total of 5000 cGy curative radiotherapy (RT). Due to pancytopenia 8 months after completion of therapy, bone marrow biopsy and aspiration were performed, and a diagnosis of myelodysplastic syndrome with excess blasts 2 (MDS-EB2) was made. Two courses of the azacitidine (75 mg/m2) protocol were administered every 28 days in the hematology clinic. Two weeks after CT the patient was transferred from the emergency department to the hematology clinic with the diagnosis of pancytopenia and febrile neutropenia. She died at the age of 33 due to sepsis that developed during follow-up.

Conclusion
Due to the rarity of BS, there is no prospective trial in patients with cancer and no evidence base upon which to design treatment programs. For these reasons, it is strongly recommended that patients receive multidisciplinary care, with precise assessment and discussion of the indication and an adequate dose of DNA-damaging agents such as chemotherapy and ionizing radiation.
3D C-arm navigated suture button implantation for AC joint dislocations - the pilot study
Authors: Böhringer Alexander , Gebhard Florian , Dehner Christoph , Eickhoff Alexander , Cintean Raffael , Pankratz Carlos , Schütze Konrad 
Published: July 2024

Abstract
Purpose
The surgical treatment of acute traumatic AC joint dislocations is still a subject of scientific debate in the literature. The arthroscopically assisted stabilization procedure with a suture button system has been successfully established and is widely used in daily practice. It is minimally invasive and allows the anatomical reconstruction of the torn coracoclavicular ligaments in one step with a permanent implant that does not have to be removed in a second operation. This clinical pilot study is the first to describe the new method of navigated suture button implantation with the future aim of further reducing surgical invasiveness and further increasing surgical precision.

Materials and methods
10 patients with a Rockwood 3b/5 injury could be included in the prospective study (DRKS00031855) within 5 months according to inclusion and exclusion criteria. Surgical stabilization was performed with a suture button system via a navigated coracoclavicular drill tunnel. Demographic and radiological data as well as information on health and shoulder function were collected from patient records, X-rays, DVT scan and 3 questionnaires (DASH, NHS and Eq. 5D) at the preoperative, intraoperative and postoperative (discharge, 6 weeks and 3 months) time points.

Results
All operations could be performed within 8.8 days (± 6.81) after trauma. The average operation time was 50.3 min (± 8.81). The mean distance of the drill hole in the clavicle to the AC joint was 26.6 mm (± 2.63). The radiologically measured vertical coracoclavicular distance was 38.8 mm (± 6.16) at discharge and 41.11 mm (± 7.51) at 3 months. This loss of reduction was not statistically significant. In contrast, the DASH, NHS and Eq. 5D results showed significant improvement from discharge to 3 months postoperatively.

Conclusion
Image-guided 3D C-arm navigated AC joint suture button stabilization is feasible in everyday surgical practice. It may be possible to achieve a further reduction in invasiveness while at the same time increasing the accuracy of implant positioning. Further clinical studies with a larger number of patients and a longer follow-up period are necessary to enable a comparison with conventional methods.
Medical imaging in cancer cachexia
Authors: Ko Hyun Soo , Attenberger Ulrike 
Published: July 2024

AbstractCancer cachexia, often referred to as “wasting syndrome,” is characterized by fatigue, weakness, and involuntary weight loss. This syndrome is concomitant with progressive skeletal muscle atrophy with or without adipose tissue loss and is frequently accompanied by systemic inflammation. Understanding the complexities of cancer cachexia is crucial for early detection and intervention, and it is also paramount for enhancing patient outcomes. Medical imaging, comprising diverse imaging modalities, plays a pivotal role in this context, facilitating the diagnosis and surveillance assessment of both the disease extent and the body composition changes that offer valuable information and insights into disease progression. This article provides a comprehensive discourse of the pathophysiological mechanisms and clinical manifestations of cancer cachexia as well as the role of medical imaging in this setting. Particular emphasis is placed on contemporary multidisciplinary and translational research efforts for the development of diagnostic and treatment tools, aiming to mitigate the devastating consequences of cancer cachexia.
Machine learning-based digital twin of a conveyor belt for predictive maintenance
Authors: Pulcini Valerio , Modoni Gianfranco 
Published: July 2024

AbstractThe problem of achieving a good maintenance plan is well-known in the modern industry. One of the most promising approaches is predictive maintenance, which schedules interventions based on predictions made by collecting and analyzing data from the process. However, to the best of the authors’ knowledge, this approach is still not widespread and known enough, and particularly, the real-case scenarios of its application appear not exhaustive. To contribute to fill this gap, this work proposes a digital twin (DT), which performs a predictive maintenance approach for a conveyor belt within a real-case scenario with the overall goal of predicting faults during normal belt operations. Specifically, the core of the implemented DT is a model that analyzes the data collected by various sensors distributed along the conveyor belt. In turn, this model exploits a machine learning-based algorithm that predicts the insurgence of faults. The tests of the developed solution, conducted within a real scenario, demonstrated good precision and accuracy in identifying the fault status and also in a time deemed acceptable for the involved stakeholders.
A stochastic approach for parameter optimization of feature detection algorithms for non-target screening in mass spectrometry
Authors: Sadia Mohammad , Boudguiyer Youssef , Helmus Rick , Seijo Marianne , Praetorius Antonia , Samanipour Saer 
Published: July 2024

AbstractFeature detection plays a crucial role in non-target screening (NTS), requiring careful selection of algorithm parameters to minimize false positive (FP) features. In this study, a stochastic approach was employed to optimize the parameter settings of feature detection algorithms used in processing high-resolution mass spectrometry data. This approach was demonstrated using four open-source algorithms (OpenMS, SAFD, XCMS, and KPIC2) within the patRoon software platform for processing extracts from drinking water samples spiked with 46 per- and polyfluoroalkyl substances (PFAS). The designed method is based on a stochastic strategy involving random sampling from variable space and the use of Pearson correlation to assess the impact of each parameter on the number of detected suspect analytes. Using our approach, the optimized parameters led to improvement in the algorithm performance by increasing suspect hits in case of SAFD and XCMS, and reducing the total number of detected features (i.e., minimizing FP) for OpenMS. These improvements were further validated on three different drinking water samples as test dataset. The optimized parameters resulted in a lower false discovery rate (FDR%) compared to the default parameters, effectively increasing the detection of true positive features. This work also highlights the necessity of algorithm parameter optimization prior to starting the NTS to reduce the complexity of such datasets.
Graphical Abstract
Development of a supramolecular solvent–based extraction method for application to quantitative analyses of a wide range of organic contaminants in indoor dust
Authors: Marcinekova Paula , Melymuk Lisa , Bohlin-Nizzetto Pernilla , Martinelli Erika , Jílková Simona Rozárka , Martiník Jakub , Šenk Petr , Kukučka Petr , Audy Ondřej , Kohoutek Jiří , Ghebremeskel Mebrat , Håland Alexander , Borgen Anders Røsrud , Eikenes Heidi , Hanssen Linda , Harju Mikael , Cebula Zofia , Rostkowski Pawel 
Published: July 2024

AbstractThis study investigates the efficacy of supramolecular solvent (SUPRAS) in extracting a diverse spectrum of organic contaminants from indoor dust. Initially, seven distinct SUPRAS were assessed across nine categories of contaminants to identify the most effective one. A SUPRAS comprising Milli-Q water, tetrahydrofuran, and hexanol in a 70:20:10 ratio, respectively, demonstrated the best extraction performance and was employed for testing a wider array of organic contaminants. Furthermore, we applied the selected SUPRAS for the extraction of organic compounds from the NIST Standard Reference Material (SRM) 2585. In parallel, we performed the extraction of NIST SRM 2585 with conventional extraction methods using hexane:acetone (1:1) for non-polar contaminants and methanol (100%) extraction for polar contaminants. Analysis from two independent laboratories (in Norway and the Czech Republic) demonstrated the viability of SUPRAS for the simultaneous extraction of twelve groups of organic contaminants with a broad range of physico-chemical properties including plastic additives, pesticides, and combustion by-products. However, caution is advised when employing SUPRAS for highly polar contaminants like current-use pesticides or volatile substances like naphthalene.
Heterogeneous shell growth of the neustonic goose barnacle Lepas anserifera
Authors: Watanabe Hiromi K. , Nagai Yukiko , Sakai Saburo , Kobayashi Genki , Yamamori Luna , Tada Noriko , Kuwatani Tatsu , Nishikawa Haruka , Horigome Takuto , Uehara Haruka , Yusa Yoichi 
Published: July 2024

AbstractFloating materials of both natural and anthropogenic origin affect marine ecosystems and human economic activities. Although the tracking of floating materials is important to manage the economic risks, it is difficult to trace them back to the events of origin, such as tsunamis and underwater volcanic eruptions. The gooseneck barnacle Lepas anserifera, a rapid colonizer in pelagic environments, is a potential “natural logger” of floating materials. In this study, we performed temperature-controlled culture experiments and growth line staining in the laboratory to quantify the growth increments of shells (scutum and tergum) consisting the capitulum of L. anserifera separately, and to examine the effects of the temperature on their growth. Following calcein staining, the growth lines of L. anserifera were visualized under a fluorescent microscope, and gross (capitular length and width) and individual (scutum and tergum) shell growth were compared. Shells grew in twice as much in the capitular length direction than in the capitular width direction owing to the larger growth increases in the scutum than in the tergum. Growth increments were unaffected by temperatures in the range from 20°C to 30°C, although the growth appeared to slow down in September and October compared with August. The stable oxygen isotope composition (δ18O) of the shells represented the water temperature as previously known, and the present results showed that 18O enriched in scutum than tergum in most cases. Further understanding for the biomineralization process of barnacles is required for the precise application of environmental proxies in barnacle shells.
Feasibility and diagnostic accuracy of fast whole-body MRI in slightly to moderately injured trauma patients
Authors: Reichel Katrin , Hahlbohm Patricia , Kromrey Marie-Luise , Nebelung Heiner , Schön Felix , Kamin Konrad , Goronzy Jens , Kühn Jens-Peter , Hoffmann Ralf-Thorsten , Blum Sophia Freya Ulrike 
Published: July 2024

Abstract
Objectives
To determine the feasibility and diagnostic accuracy of fast whole-body magnetic resonance imaging (WB-MRI) compared to whole-body computed tomography (WB-CT) in detecting injuries of slightly to moderately injured trauma patients.

Materials and methods
In a prospective single-center approach, trauma patients from convenience sampling with an expected Abbreviated Injury Scale (AIS) score ≤ 3 at admission, received an indicated contrast-enhanced WB-CT (reference standard) and a plain WB-MRI (index test) voluntarily up to five days after trauma. Two radiologists, blinded to the WB-CT findings, evaluated the absence or presence of injuries with WB-MRI in four body regions: head, torso, axial skeleton, and upper extremity. Diagnostic accuracy was determined using sensitivity, specificity, positive predictive value, and negative predictive value by body region.

Results
Between June 2019 and July 2021, 40 patients were assessed for eligibility of whom 35 (median age (interquartile range): 50 (32.5) years; 26 men) received WB-MRI. Of 140 body regions (35 patients × 4 regions), 31 true positive, 6 false positive, 94 true negative, and 9 false negative findings were documented with WB-MRI. Thus, plain WB-MRI achieved a total sensitivity of 77.5% (95%-confidence interval (CI): (61.6–89.2%)), specificity of 94% (95%-CI: (87.4–97.8%)), and diagnostic accuracy of 89.3% (95%-CI: (82.9–93.9%)). Across the four regions sensitivity and specificity varied: head (66.7%/93.1%), torso (62.5%/96.3%), axial skeleton (91.3%/75%), upper extremity (33.3%/100%). Both radiologists showed substantial agreement on the WB-MRI reading (Cohen’s Kappa: 0.66, 95%-CI: (0.51–0.81)).

Conclusion
Regarding injury detection, WB-MRI is feasible in slightly to moderately injured trauma patients, especially in the axial skeleton.

Clinical relevance statement
Besides offering a radiation-free approach, whole-body MRI detects injuries almost identically to whole-body CT in slightly to moderately injured trauma patients, who comprise a relevant share of all trauma patients.

Key Points

Whole-body MRI could offer radiation-free injury detection in slightly to moderately injured trauma patients.

Whole-body MRI detected injuries almost identically compared to whole-body CT in this population.

Whole-body MRI could be a radiation-free approach for slightly to moderately injured young trauma patients.
Effect of agricultural management system (“cash crop”, “livestock” and “climate optimized”) on nitrous oxide and ammonia emissions
Authors: Well Reinhard , Ruoss Nicolas , Grosz Balazs , Brunotte Joachim , Buchen-Tschiskale Caroline , Lewicka-Szczebak Dominika , Schäfer Bernhard C. 
Published: July 2024

AbstractThe study aimed to measure soil-atmosphere N2O fluxes and their controlling factors, as well as NH3 emissions and yields for two soils (silt loam and clay loam) in three management systems over two years under subsequent wheat and maize cultivation. The management systems were characterized as follows: (1) cash crop (C) with mineral fertilizer and conventional tillage; (2) livestock (L) with biogas residue fertilization and its incorporation prior to sowing in maize and reduced tillage; and (3) climate optimized (O) with minimum tillage, 8-year crop rotation, with biogas residue fertilization, in maize without incorporation in clay loam soil or incorporation by strip-tillage prior to seeding in silt loam soil. Stable isotope ratios of N2O and mineral N were determined to identify N2O processes. Within the organically fertilized maize treatments, cumulative N2O fluxes were highest in the O-system treatments of both sites (4.0 to 9.4 kg N ha− 1 a− 1), i.e. more than twice as high as in the L-system (1.5 to 3.1 kg N ha− 1 a− 1). Below root-strip till fertilizer application did not enhance N2O fluxes. Fluxes with mineral fertilization of wheat (1.1 to 3.1 kg N ha− 1 a− 1) were not different from those with organic fertilization. Isotopic values of emitted N2O revealed that bacterial denitrification dominated most of the peak flux events, while the N2O/(N2 + N2O) ratio of denitrification was mostly between 0.1 and 0.5. It can be concluded that, contrary to the intention to lower greenhouse gas fluxes by the O-system management, the highest N2O fluxes occurred in the O-system without biogas digestate incorporation in maize. With respect to NH3 fluxes, we could confirm that the application of digestate application in growing crops without incorporation or late incorporation in fertilization before sowing induces high fluxes. The beneficial aspects of the O-system including more stable soil structure and resource conservation, are thus potentially counteracted by increased N2O and NH3 emissions.