bluuebunny/crossref_metadata_2025_split huggingface dataset:
An evaluation of prenatal ultrasound screening for CTEV
Authors: Pullinger M. , Southorn T. , Easton V. , Hutchinson R. , Smith R. P. , Sanghrajka A. P. 
Published: July 2014

Congenital Talipes Equinovarus (CTEV) is one of the most common congenital limb deformities. We reviewed the records of infants who had received treatment for structural CTEV between 1 January 2007 and 30 November 2012. This was cross-referenced with the prenatal scans of mothers over a corresponding period of time. We investigated the sensitivity, specificity, and positive and negative predictive values of the fetal anomaly scan for the detection of CTEV and explored whether the publication of Fetal Anomaly Screening Programme guidelines in 2010 affected the rate of detection.During the study period there were 95 532 prenatal scans and 34 373 live births at our hospital. A total of 37 fetuses with findings suggestive of CTEV were included in the study, of whom 30 were found to have structural CTEV at birth. The sensitivity of screening for CTEV was 71.4% and the positive predictive value was 81.1%. The negative predictive value and specificity were more than 99.5%. There was no significant difference between the rates of detection before and after publication of the guidelines (p = 0.5).We conclude that a prenatal fetal anomaly ultrasound screening diagnosis of CTEV has a good positive predictive value enabling prenatal counselling. The change in screening guidance has not affected the proportion of missed cases. This information will aid counselling parents about the effectiveness and accuracy of prenatal ultrasound in diagnosing CTEV.Cite this article: Bone Joint J 2014;96-B:984–8.
Does the length of incision in the quadriceps affect the recovery of strength after total knee replacement?
Authors: Chareancholvanich K. , Pornrattanamaneewong C. 
Published: July 2014

We have compared the time to recovery of isokinetic quadriceps strength after total knee replacement (TKR) using three different lengths of incision in the quadriceps. We prospectively randomised 60 patients into one of the three groups according to the length of incision in the quadriceps above the upper border of the patella (2 cm, 4 cm or 6 cm). The strength of the knees was measured pre-operatively and every month post-operatively until the peak quadriceps torque returned to its pre-operative level.There was no significant difference in the mean operating time, blood loss, hospital stay, alignment or pre-operative isokinetic quadriceps strength between the three groups. Using the Kaplan–Meier method, group A had a similar mean recovery time to group B (2.0 ± 0.2 vs 2.5 ± 0.2 months, p = 0.176). Group C required a significantly longer recovery time (3.4 ± 0.3 months) than the other groups (p < 0.03). However, there were no significant differences in the mean Oxford knee scores one year post-operatively between the groups.We conclude that an incision of up to 4 cm in the quadriceps does not delay the recovery of its isokinetic strength after TKR.Cite this article: Bone Joint J 2014;96-B:902–6.
Standardised effect sizes in clinical research
Authors: Parsons N. , Griffin X. L. , Stengel D. , Carey Smith R. , Perry D. C. , Costa M. L. 
Published: July 2014

The Bone & Joint Journal provides the latest evidence to guide the clinical practice of orthopaedic surgeons. The benefits of one intervention compared with another are presented using outcome measures; some may be specific to a limb or joint and some are more general health-related quality of life measures. Readers will be familiar with many of these outcome measures and will be able to judge the relative benefits of different interventions when measured using the same outcome tool; for example, different treatments for pain in the knee measured using a particular knee score. But, how should readers compare outcomes between different clinical areas using different outcome measures? This article explores the use of standardised effect sizes. Cite this article: Bone Joint J 2014;96-B:853–4.
Failure in the application of fragility fracture prevention guidelines
Authors: Elvey MH , Pugh H , Schaller G , Dhotar G , Patel B , Oddy MJ 
Published: July 2014

Introduction The cost of fragility fractures to the UK economy is predicted to reach £2.2 billion by 2025. We studied our hip fracture population to establish whether national guidelines on fragility fracture prevention were being followed, and whether high risk patients were identified and treated by local care services. Methods Data on a consecutive series of trauma hip fracture admissions were collected prospectively over 14 months. National Institute for Health and Care Excellence (NICE) and National Osteoporosis Guideline Group (NOGG) recommendations and FRAX® risk calculations were applied to patients prior to their admission with a new hip fracture. Results Overall, 94 patients were assessed against national guidelines. The mean population age was 77 years. Almost a quarter (22%) of patients had suffered a previous fragility fracture. The mean FRAX® ten-year probability of hip fracture was 7%. According to guidelines, 45% of the study population required treatment, 35% fulfilled criteria for investigation and reassessment, and 20% needed no further management. In practice, 27% received treatment, 4% had undergone dual energy x-ray absorptiometry and were untreated, and 69% had not been investigated and were untreated. In patients meeting intervention thresholds, only 33% of those who required treatment were receiving treatment in practice. Conclusions In conjunction with NICE and NOGG recommendations, FRAX® was able to identify 80% of our fracture population as intermediate or high risk on the day of fracture. Correct management was evident in a third of cases with a pattern of inferior guideline compliance seen in a London population. There remains a lack of clarity over the duty of care in fragility fracture prevention.
Breast cancer survivors’ perspectives on whether clinical staff should ask breast cancer patients about childhood abuse
Authors: Clark L , Holcombe C , Fisher J , Salmon P 
Published: July 2014

Introduction Recent studies have shown that women who recall childhood abuse are at increased risk of emotional problems following a breast cancer diagnosis. How services should respond is unclear given the risk of compounding the emotional trauma of cancer with questioning about abuse. Our aim was to present the research findings to women with experience of breast cancer so as to obtain their perspective on how this evidence should influence clinical practice. Methods Participants were women who had been treated for breast cancer at one of the study units and women with a history of breast cancer who were members of a local patient support group. Three focus groups were conducted (with six, five and three participants respectively). The interview transcripts were analysed qualitatively. Results Participants emphasised the importance of the research findings for cancer care. The consensus was that abuse and its consequences for patients being treated for cancer should not be a ‘taboo’ area, and that patients should be given the opportunity and choice to disclose abuse as part of a holistic programme of care. Conclusions Services should examine how to include prompts about abuse as part of routine holistic assessment by clinical staff, who will need to be trained in eliciting and managing disclosures of abuse.
Arquivo do Convento da Madre de Deus de Sá de Aveiro
Authors: Cartaxo Capelo Ludovina 
Published: July 2014

O Mosteiro da Madre de Deus de Sá de Aveiro, era feminino e pertencia à ordem de S. Francisco. Fundado em 1644, enfrentou desde o início uma forte oposição por parte de Filipe Barreto Sernige, descendente dos Sernige, que lutou pelos seus direitos ao morgado. Esta contenda levou a que o Mosteiro perdesse o Morgado de Sernige. O Mosteiro da Madre de Deus de Sá de Aveiro recebeu ao longo da sua vida educandas, corista, seculares e criadas, cujas idades de entrada balizam-se entre os 3 e os 50 anos de idade, e que de alguma forma educou, protegeu e preparou para a vida. A sua documentação diz essencialmente respeito ao governo administrativa e patrimonial dos seus bens e rendimentos. O presente trabalho pretende dar a conhecer o fundo documental do Cartório do Mosteiro da Madre de Deus de Sá de Aveiro, dispõem assim os investigadores de mais informação organizada para explorar Abstract The Monastery of the Mother of God of Sá from Aveiro, was feminine and belonged to the order of S. Francisco. Founded in 1644, it faced since the beginning a strong opposition from Filipe Barreto Sernige, a descendant of the Sernige’s, who fought for his rights to the majorat. This contest led to the Monastery loosing Sernige majorat. The Monastery of the Mother of God of Sá of Aveiro received throughout his life girlstudents, showgirls, nuns and housemaids, whose ages were delimited in between 3 and 50 years old, and that in some way it educated, protected and prepared for life. It’s documentation will involve mainly administrative and patrimonial management of its property and income. This paper intends to show the documental fund from the Office of the Monastery of the Mother of God of Sá of Aveiro, as well as to provide to researchers more organized information to explore.
Appendicular osteosarcoma in small-breed dogs: 51 cases (1986–2011)
Authors: Amsellem Pierre M. , Selmic Laura E. , Wypij Jackie M. , Bacon Nicholas J. , Culp William T. N. , Ehrhart Nicole P. , Powers Barbara E. , Stryhn Henrik , Farese James P. 
Published: July 2014

Abstract
Objective—To describe outcomes for small-breed dogs with appendicular osteosarcoma.
Design—Multi-institutional retrospective case series.
Animals—51 small-breed dogs.
Procedures—Records from participating Veterinary Society of Surgical Oncology members were searched for dogs that weighed ≤ 15 kg (33 lb) with a histologic diagnosis of appendicular osteosarcoma. The Kaplan-Meier method was used to determine median survival times (MSTs), and Cox regression was performed to identify variables associated with survival time.
Results—Tumors were most commonly located on the humerus (n = 15) and femur (14). Of the 51 study dogs, 9 were treated nonsurgically, 16 underwent amputation of the affected limb only, and 26 underwent curative-intent treatment, with MSTs of 112, 257, and 415 days, respectively. The MST did not differ significantly between dogs in the amputation-only and curative-intent groups. For dogs in the nonsurgical group, MST decreased significantly as the tumor histologic score increased. For dogs in the amputation-only group, MST decreased as body weight increased.
Conclusions and Clinical Relevance—For the small-breed dogs with appendicular osteosarcoma of the present study, tumor histologic grade and mitotic index were subjectively lower and MST following amputation of the affected limb without adjuvant chemotherapy was longer, compared with those for similarly affected larger dogs. Results indicated no significant advantage in MST for dogs that underwent curative-intent treatment versus dogs that underwent amputation only, and further investigation of the importance of adjuvant chemotherapy is warranted.