bluuebunny/crossref_metadata_2025_split huggingface dataset:
Susceptibility to injury during a fall among blind children
Authors: Boguszewski Dariusz , Zabłocka Martyna , Adamczyk Jakub 
Published: September 2013

Abstract
Introduction: The aim of this study was examine the relationship between ability of safe falls and occurrence injuries from the effect of falls, among blind children.
Material and methods: More than one hundred children (10-16 years old) was in research and control groups. In the research group was 51 blind people, in control group 66 sighted in a proper manner. Test of Susceptibility to Injury During the Falls (TSIDF) by Kalina and interview directed to determine the number and frequency of falls and their consequences (number and type of injuries) and selected lifestyle factors were used as a research tools.
Results: Blind children made more mistakes in test (TSIDF) than their non-disabled peers (although they are trained to safe falls). This may prove that a high susceptibility to injury of the children from the research group. However blind people had more injuries after the falls. Study confirmed positive effect of physical activity on the level of safe falls skills.
Conclusion: Physical fitness, physical activity and especially exercises of safe falls skills can be important element of prevention of falls. This concern to high-risk groups, such as blind people.
Influence of Asymmetrical Tonic Neck Reflex on motor development of infants with hypotony of posture
Authors: Poklękowska Katarzyna , Suchocka Joanna 
Published: September 2013

Abstract
Introduction: One of the commonly used terms in the assessment of CNS functioning is muscle tone. In literature we can find many different and not standardized definitions. Postural tone depends on topographic distribution in proximal and distal parts of body and antigravital activity. For diagnostic and therapeutic purpose the term postural tone is used.
The aim of this study was to assess (monitoring) the psychomotor development of infants between 2 months and 2 years of life with abnormal posture tone (hypotonia of posture) and asymmetry of postural and motor patterns. Infants participated in NDT-Bobath therapeutic intervention.
Material and methods: 65 infants fulfilling specified criteria were examined during 2 years of prospective study. According to hypotonic type, infants were divided into two groups. The presence of asymmetrical tonic neck activity in spontaneous movements was coded in two-points scale (1 or 2).
Results: All infants were examined at first visit with INSITE developmental scale which displayed psychomotor retardation. At the age of 2 years, only 21,87% from first group and 100% from second group still were assessed as retarded.
Conclusions: Disintegrated activity ATOS decreased the level of motor development of 24-month-old infants even to 4 months of developmental age. In the second group, the number of infants with more disorders in quality of movement and decreased final developmental age is much bigger.
Research ethics – from ethos to regulations
Authors: Przyłuska-Fiszer Alicja 
Published: September 2013

Abstract
This paper has three aims. First, to present main principles for responsible conduct of research in the light of ethos of researchers and goals of science. Secondly, to describe the problem of scientific misconduct and strategies of preventing and dealing with it adopted by different Polish and international institutions. Thirdly, to analyze causes of growing institutionalization of research ethics
Research in physiotherapy – selected problems
Authors: Chudobina Aleksandra , Pilch Anna 
Published: September 2013

Abstract
Research in the field of physiotherapy creates some controversy. This article seeks to explore and find out the solutions for this issue. Two aspects are discussed: the difficulties in reconciling the specificity of physiotherapy research with methodological standards and the concerns related to patients’ participation in the research. These problems affect the physiotherapists involved in the creation of ethically and methodologically valuable research project. Physiotherapists conducting research struggle to reconcile two sets of values: the role of a researcher and the role of a professional helper. This article discusses the possibility of creating a valuable research project based on the methodological standards within EBM paradigm in relation to the practical aspects of physiotherapy, such as therapy effectiveness and patient-therapist interaction.
Ethical and legal aspects of scientific research on data collected in medical records
Authors: Staszewska Anna , Sierocka Aleksandra , Marczak Michał 
Published: September 2013

Abstract
Research on medical data is essential to the development of evidence based medicine. The use of medical data for scientific purposes must follow principles of good research practice and all relevant legal requirements. The aim of this article is to discuss ethical and legal aspects of processing, preparation and identification of medical data that were used by one of the authors for her doctoral research. The research deals with the black spots methods as a tool for minimizing risks of adverse events in medical setting. It must be stressed, that analyses presented in this article apply to research conducted by physicians as well as to research on medical data undertaken by representative of other medical professions, in particular physiotherapists.
To Be or Not to Be Invited Youth Sport: Young People’s Influence in Voluntary Sport
Authors: Larsson Lena , Meckbach Jane 
Published: September 2013

AbstractInfluence and the opportunity to have one’s voice heard are fundamental rights valid for all people, including also children and youths. Despite this, research shows that young people’s voices have received less attention and young people have no influence in many contexts in which they find themselves (Evans, 2007; Fundberg, 2009; Redelius, 2005). In Sweden, the emphasis on influence can be linked to the fact that the sport club activities of the Swedish state are seen as an important arena for the civic education of young people (The Swedish Sports Confederation, 2005, 2011). The aim of this study is to explore young coaches and their opportunities to influence in the Swedish sport clubs with focus on what the youths themselves say about influence and power. We use Bourdieus’ theories on social fields to bring to light which youths are chosen to be leaders and their possibilities to influence. The results show that for young coaches to have influence, both their habitus and capital are required to ‘match’ the social context into which they are entering. One way of maintaining power is not to change the accepted way of working, which excludes the young coaches from challenging in the battle for positions.
Evaluating Nicotine Levels Selection and Patterns of Electronic Cigarette use in a Group of “Vapers” Who Had Achieved Complete Substitution of Smoking
Authors: Farsalinos Konstantinos E. , Romagna Giorgio , Tsiapras Dimitris , Kyrzopoulos Stamatis , Voudris Vassilis 
Published: September 2013

Background Electronic cigarettes (ECs) are alternative-to-smoking nicotine delivery devices; consumers (commonly called vapers) use them in order to reduce or completely substitute smoking. The European Commission has released a proposal for a new Tobacco Product Directive that might reduce availability of nicotine-containing products, including ECs. In this study, the EC use patterns in subjects who have completely substituted smoking with EC use were examined by personal interviews. The study focused on nicotine levels used in order to achieve smoking cessation, reported benefits, associated side effects, and estimation of EC dependence compared with smoking. Methods Participants were 111 subjects who had completely substituted smoking with EC use for at least 1 month. Smoking abstinence was validated by measuring blood carboxyhemoglobin levels. Nicotine levels at initiation of EC use, at time of smoking cessation, and at time of interview were recorded. Dependence potential was assessed by asking the first question of the Fagerström Test for Cigarette Dependence (time until smoking the first cigarette and until first use of EC in the morning) and questions about perceived past dependence on tobacco cigarettes and present dependence on EC. Results Forty-two percent of participants reported quitting smoking during the first month of EC use. Liquids with nicotine concentration >15 mg/mL were used by 74% of users at initiation of EC use, while 16.2% had to increase the initial nicotine levels in order to achieve complete smoking abstinence. Seventy-two participants (64.9%) reported that from the time of smoking cessation to the time of the interview (8 months median duration of EC use) they reduced the nicotine concentration they were consuming; however, only 12% of the total sample was using ≤5 mg/mL nicotine concentration at the time of the interview. Side effects were mild and temporary. The vast majority of participants reported better exercise capacity and improved olfactory and gustatory senses. Perceived EC dependenct was significantly lower compared to smoking. Conclusions Nicotine levels appear to play an important role in achieving and maintaining smoking cessation in the group of motivated subjects studied. High nicotine-containing liquids were used while few mild and temporary side effects were reported. Proposals about regulation should consider the pragmatic use patterns of ECs, especially in consumers who have completely substituted smoking.
La littérature française du Moyen Âge au Québec : trente ans de recherche (1980-2012)1
Authors: Kogen Helena 
Published: September 2013

Bon nombre d’universités québécoises — l’Université de Montréal, l’Université du Québec à Montréal, l’Université Laval, mais aussi l’Université McGill et l’Université Concordia — offrent des programmes d’étude et de recherche dans le domaine de la littérature du Moyen Âge français. Le présent article offre, à travers les travaux les plus importants des chercheurs, les mutations institutionnelles et les rencontres scientifiques, un regard sur l’histoire riche et mouvementée de cette discipline au Québec au cours des 30 dernières années, ainsi qu’une réflexion sur ses enjeux actuels.
Les études québécoises : institutions, regroupements, programmes, avenir
Authors: Chartier Daniel 
Published: September 2013

Que pouvons-nous conclure de l’évolution des études québécoises, tant à l’étranger qu’au Québec, au niveau de leur structuration, de leurs projets porteurs, de leurs professeurs et de leurs étudiants des cycles supérieurs ? Doit-on s’inquiéter, ou simplement constater des changements normaux au cours des dernières décennies, notamment en faveur d’une multiplicité des corpus étudiés et enseignés, qui incluent toutefois le Québec ? Dans cet article, l’auteur rappelle le développement institutionnel de l’étude du Canada français, puis du Québec, à compter de la Révolution tranquille, dans la foulée de celui des area studies telles qu’on les concevait alors aux États-Unis. Il présente aussi l’état de l’organisation de la recherche au Québec et quelques-uns des résultats inédits obtenus à la suite d’une étude sur la place du Québec dans les programmes universitaires. Ceci permet de constater que l’évolution récente des études sur le Québec n’indique pas leur déclin, mais au contraire une vitalité tant dans l’enseignement des disciplines que dans des projets intégrateurs interdisciplinaires.
Points tournants. Bilan et perspectives des études théâtrales au Québec
Authors: Jubinville Yves 
Published: September 2013

Où en est la recherche en études théâtrales ? Dans le bilan que nous proposons, il s’agit de mettre en lumière les développements successifs d’un champ d’activité relativement nouveau au Québec en prenant en compte des questions relatives aux délimitations de l’objet d’analyse qu’est le théâtre et en dressant le paysage des savoirs spécifiques à ce domaine de recherche qui ont été élaborés sur une période de 30 ans. Cette réflexion s’intéresse également aux médiations et aux réseaux par lesquels ce savoir circule et contribue, le cas échéant, à modifier la compréhension qui se dégage des pratiques scéniques et dramaturgiques et de leur évolution dans le contexte particulier du Québec. Partant du cas de L’Annuaire théâtral, seule revue savante dans le domaine au Québec, ce bilan n’ignore pas néanmoins le cadre international de production de la recherche théâtrale québécoise. Il en sera question largement lorsqu’il s’agira d’évaluer les retombées de la recherche, d’identifier des tendances et des voies possibles de renouveau.
Building the Women's Health Research Workforce: Fostering Interdisciplinary Research Approaches in Women's Health
Authors: Nagel Joan D. , Koch Abby , Guimond Jennifer M. , Glavin Sarah , Geller Stacie 
Published: September 2013

Background: The Building Interdisciplinary Research Careers in Women's Health (BIRCWH) program is a mentored institutional research career development program developed to support and foster the interdisciplinary research careers of men and women junior faculty in women's health and sex/gender factors. The number of scholars who apply for and receive National Institutes of Health (NIH) research or career development grants is one proximate indicator of whether the BIRCWH program is being successful in achieving its goals. Primary Study Objective: To present descriptive data on one metric of scholar performance—NIH grant application and funding rates. Methods/Design: Grant applications were counted if the start date was 12 months or more after the scholar's BIRCWH start date. Two types of measures were used for the outcome of interest—person-based funding rates and application-based success rates. Main Outcome Measures: Grant application, person funding, and application success rates. Results: Four hundred and ninety-three scholars had participated in BIRCWH as of November 1, 2012. Seventy-nine percent of BIRCWH scholars who completed training had applied for at least one competitive NIH grant, and 64% of those who applied had received at least one grant award. Approximately 68% of completed scholars applied for at least one research grant, and about half of those who applied were successful in obtaining at least one research award. Men and women had similar person funding rates, but women had higher application success rates for R01 grants. Limitations: Data were calculated for all scholars across a series of years; many variables can influence person funding and application success rates beyond the BIRCWH program; and lack of an appropriate comparison group is another substantial limitation to this analysis. Conclusion: Our results suggest that the BIRCWH program has been successful in bridging advanced training with establishing independent research careers for scholars.
Three-Year Outcomes of 6-Month Paliperidone Palmitate in Adults With Schizophrenia
Authors: Correll Christoph U. , Johnston Karen , Turkoz Ibrahim , Gray Jason , Sun Liping , Doring Monica , Sajatovic Martha 
Published: July 2024

ImportanceLong-acting injectable (LAI) antipsychotics have the potential to improve adherence and symptom control in patients with schizophrenia, promoting long-term recovery. Paliperidone palmitate (PP) once every 6 months is the first and currently only LAI antipsychotic with an extended dosing interval of 6 months.ObjectiveTo assess long-term outcomes of PP received once every 6 months in adults with schizophrenia.Design, Setting, and ParticipantsIn a 2-year open-label extension (OLE) study of a 1-year randomized clinical trial (RCT), eligible adults with schizophrenia could choose to continue PP every 6 months if they had not experienced relapse after receiving PP once every 3 or 6 months in the 1-year, international, multicenter, double-blind, randomized noninferiority trial. The present analysis focused on patients receiving PP every 6 months in the double-blind trial through the OLE study (November 20, 2017, to May 3, 2022).InterventionPatients received a dorsogluteal injection of PP on day 1 and once every 6 months up to month 30.Main Outcomes and MeasuresEnd points included assessment of relapse and change from the double-blind trial baseline to the OLE end point in Positive and Negative Syndrome Scale (PANSS) total and subscale, Clinical Global Impression–Severity (CGI-S) Scale, and Personal Social Performance (PSP) Scale scores. Treatment-emergent adverse events (TEAEs), injection site evaluations, and laboratory tests were also assessed.ResultsAmong 121 patients (83 [68.6%] male), mean (SD) age at baseline was 38.6 (11.24) years and mean (SD) duration of illness was 11.0 (9.45) years. At screening of the double-blind study, 101 patients (83.5%) were taking an oral antipsychotic and 20 (16.5%) were taking an LAI antipsychotic. Altogether, 5 of 121 patients (4.1%) experienced relapse during the 3-year follow-up; reasons for relapse were psychiatric hospitalization (2 [1.7%]), suicidal or homicidal ideation (2 [1.7%]), and deliberate self-injury (1 [0.8%]). Patients treated with PP every 6 months were clinically and functionally stable, and outcomes were well maintained, evidenced by stable scores on the PANSS (mean [SD] change, −2.6 [9.96] points), CGI-S (mean [SD] change, −0.2 [0.57] points), and PSP (mean [SD] change, 3.1 [9.14] points) scales over the 3-year period. In total, 101 patients (83.5%) completed the 2-year OLE. At least 1 TEAE was reported in 97 of 121 patients (80.2%) overall; no new safety or tolerability concerns were identified.Conclusions and RelevanceIn a 2-year OLE study of a 1-year RCT, results supported favorable long-term outcomes of PP once every 6 months for up to 3 years in adults with schizophrenia.
Martin's Sulfurane
Authors: Roden Brian A. , Gennaiou Kyriaki , Kourgiantaki Maria , Mazaraki Kalliopi , Zografos Alexandros L. 
Published: July 2024

Abstract

image

[

32133‐82‐7

]

C
30
H
20
F
12
O
2
S

(MW 672.57)

InChI =
1S/C30H20F12O2S/c31‐27(32,33)25(28(34,35)36,21‐13‐5‐1‐6‐14‐21)43‐45(23‐17‐9‐3‐10‐18‐23,24‐19‐11‐4‐12‐20‐24)44‐26(29(37,38)39,30(40,41)42)22‐15‐7‐2‐8‐16‐22/h1‐20H

InChIKey =
RMIBJVUYNZSLSD‐UHFFFAOYSA‐N

(dehydration of alcohols;

2

synthesis of epoxides and cyclic ethers;

3

cleavage of amides;

5

oxidation of amines

6

)

Physical Data
: mp 107–109 °C.

Solubility
: sol ether, benzene, acetone, alcohols.

Form Supplied in
: white crystals.

Analysis of Reagent Purity
: NMR, IR.

Preparative Method
: by the reaction of the potassium salt of 1,1,1,3,3,3‐hexafluoro‐2‐phenylisopropanol with diphenyl sulfide in the presence of chlorine in ether at −78 °C.

1

a

Handling, Storage, and Precautions
: avoid moisture; readily hydrolyzed; stable at rt; decomposes slowly at rt in solution.
Oxygen‐Vacancy‐Assisted Dual Functional Surface Coatings Suppressing Irreversible Phase Transition of Li‐Rich Layered Oxide Cathodes
Authors: Jiang Qinting , Li Xifei , Hao Youchen , Zuo Jiaxuan , Duan Ruixian , Li Jun , Cao Guiqiang , Wang Jingjing , Wang Jing , Li Ming , Yang Xuan , Li Mengjiao , Li Wenbin , Xi Yukun , Zhang Jianhua , Xiao Wei 
Published: July 2024

AbstractBoth lattice oxygen release and the migration of transition metal (TM) ions challenge the cyclability of Li‐rich Mn‐based layered oxide (LMO) cathodes by inducing irreversible phase transitions. In this work, the oxygen‐vacancy‐assisted dual functional surface coatings of Li‐rich layered oxide cathodes, including a spinel‐over‐phase and a Li3PO4 layer are fabricated for lithium‐ion batteries (LIBs). The functional role of the optimized interface is mainly focused. Specifically, during the process of reorganized surface structure, the oxygen vacancies function as active sites for migrating TM ions to form the spinel over‐phase and deliver the decreased binding energy of PO43− on the LMO surface. It is found that the Li3PO4 layer increases the migration energy barrier of TM ions to 13.38 eV (7.62 eV for LMO). As a result, both the spinel over‐phase and the Li3PO4 layer synergistically inhibited the irreversible phase transitions of LMO upon cycling to boost lithium storage of the cathodes. The optimized cathode maintained higher capacity retention of 95% at 0.2 C after 200 cycles in comparison to 67% for the pristine LMO. This study provides some understanding of the functional roles of the optimized dual surface coatings in suppressing the irreversible phase transition of LMO for LIBs.
Integration of High‐Tc Superconductors with High‐Q‐Factor Oxide Mechanical Resonators
Authors: Manca Nicola , Kalaboukhov Alexei , Plaza Alejandro E. , Cichetto Leonélio , Wahlberg Eric , Bellingeri Emilio , Bisio Francesco , Lombardi Floriana , Marré Daniele , Pellegrino Luca 
Published: July 2024

AbstractMicro‐mechanical resonators are building blocks of a variety of applications in basic science and consumer electronics. This device technology is mainly based on well‐established and reproducible silicon‐based fabrication processes with outstanding performances in term of mechanical Q‐factor and sensitivity to external perturbations. Broadening the functionalities of micro‐electro‐mechanical systems (MEMS) by the integration of functional materials is a key step for both applied and fundamental science. However, combining functional materials with silicon‐based devices is challenging. An alternative approach is directly fabricating MEMS based on compounds inherently showing non‐trivial functional properties, such as transition metal oxides. Here, a full‐oxide approach is reported, where a high‐ superconductor YBa2Cu3O7 (YBCO) is integrated with high Q‐factor micro‐bridge resonators made of single‐crystal LaAlO3 (LAO) thin films. LAO resonators are tensile strained, with a stress of about 350 MPa, show a Q‐factor above 200k, and have low roughness. YBCO overlayers are grown ex situ by pulsed laser deposition and YBCO/LAO bridges show zero resistance below 78 K and mechanical properties similar to those of bare LAO resonators. These results open new possibilities toward the development of advanced transducers, such as bolometers or magnetic field detectors, as well as experiments in solid state physics, material science, and quantum opto‐mechanics.
Continuous Manufacturing of Bioinspired Bone‐Periosteum Integrated Scaffold to Promote Bone Regeneration
Authors: Li Zhengwei , Li Shun , Gao Chongjian , Liu Juan , Qu Huawei , Yang Jirong , Lu William Weijia , Ruan Changshun , Niu Xufeng 
Published: July 2024

AbstractThe scaffold that bioinspired natural bone‐periosteum is ideal for the repair of bone defects, while the achievement of a gradient scaffold with an integrated and stable interface remains challenging. Herein, a bioinspired bone‐periosteum integrated collagen‐based scaffold is developed, in which the top layer is electrospun collagen‐dense scaffold as bioinspired periosteum (BP) to prevent invasion of reticular fiber tissue and the bottom layer is in situ mineralized collagen scaffold (IMCS) to promote osteogenic differentiation. Owing to the proposed continuous manufacturing of successive 3D printing and electrospinning, the integrated scaffold (BP‐IMCS) comprised of BP and IMCS demonstrates excellent structural stability, ten times higher than that of direct‐combination scaffolds. Besides, in vivo implantation results confirmed that BP‐IMCS significantly improves new bone formation up to 32.47%, better than an individual layer, due to its co‐work of mineral ions and bioinspired structure. Therefore, this study offers a continuous manufacturing strategy to realize the integrated and interface‐stable bone‐periosteum structure, providing new solutions for heterostructure tissue fabrication.