bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: A Non‐Photochemical Route to Synthesize Simple Benzo[1,2‐b:4,3‐b′]dithiophenes: FeCl3‐Mediated Cyclization of Dithienyl Ethenes.
Authors: Cauteruccio Silvia , Dova Davide , Graiff Claudia , Carrara Claudio , Doulcet Julien , Stephenson G. Richard , Licandro Emanuela 
Published: October 2014

AbstractThe cyclization of α,α′‐disubstituted (Z)‐dithienylethenes (I) proceeds readily in the presence of FeCl3 to afford desired benzo[1,2‐b:4,3‐b′]dithiophenes (III).
ChemInform Abstract: Organocatalytic Enantioselective Friedel—Crafts Reaction of 1‐Naphthols with Isatins and an Unexpected Spontaneous Dehydration Process.
Authors: Wu Deyan , Zhang Xuwen , Xu Yong , Xue Yingfei , Li Jian , Wang Wei , Zhu Jin 
Published: October 2014

AbstractThe enantioselective Friedel—Crafts reaction of 1‐naphthols with isatins and subsequent treatment of the products with ethyl iodide gives compounds (IV) with good to high enantioselectivities.
ChemInform Abstract: Organocatalytic Asymmetric Conjugate Addition of 2‐Oxindole‐3‐carboxylate Esters to 2‐Phthalimido Acrylates: Efficient Synthesis of Cγ‐Tetrasubstituted α‐Amino Acid Derivatives.
Authors: Gao Juan , Chen Jia‐Rong , Duan Shu‐Wen , Li Tian‐Ren , Lu Liang‐Qiu , Xiao Wen‐Jing 
Published: October 2014

AbstractAn asymmetric conjugate addition of 2‐oxoindole‐3‐carboxylates to 2‐activated phthalimidoacrylates using a bifunctional cinchona‐derived thiourea as the catalyst is presented.
ChemInform Abstract: Asymmetric Diels—Alder Reactions of 2,4,6‐Trienals via Tetraenamine Catalysis.
Authors: Zhou Qing‐Qing , Xiao You‐Cai , Yuan Xin , Chen Ying‐Chun 
Published: October 2014

AbstractThe asymmetric Diels—Alder cycloaddition of trienals (I) and (IV) and 3‐methylene oxindole derivatives and a related benzofuranone proceeds through the formation of a tetraenamine intermediate generated from the (S)‐diphenylprolinol‐derived catalyst and the trienal.
ChemInform Abstract: Synthesis of Boc‐Protected 4,5‐Methano‐β‐proline.
Authors: Tymtsunik Andriy V. , Ivon Yevhen M. , Komarov Igor V. , Grygorenko Oleksandr O. 
Published: October 2014

AbstractBoth cis‐ and trans‐isomers of the title compound are synthesized in 49% total yield.
ChemInform Abstract: [3 + 2] Photooxygenation of Aryl Cyclopropanes via Visible Light Photocatalysis.
Authors: Lu Zhan , Parrish Jonathan D. , Yoon Tehshik P. 
Published: October 2014

AbstractA wide range of electron‐rich aryl cyclopropanes participate in aerobic [3 + 2] photooxygenation reactions upon irradiation with visible light in the presence of a Ru‐bipyrazine catalyst.
ChemInform Abstract: Structures and Reactivities of Iminium Ions Derived from Substituted Cinnamaldehydes and Various Chiral Imidazolidin‐4‐ones.
Authors: An Feng , Paul Shyeni , Ammer Johannes , Ofial Armin R. , Mayer Peter , Lakhdar Sami , Mayr Herbert 
Published: October 2014

AbstractThe reaction of the imidazolidinonium hexafluorophosphate with cinnamic aldehydes provides a range of iminium hexafluorophosphates.
ChemInform Abstract: Facile Synthesis of Highly Substituted 2‐Pyrone Derivatives via a Tandem Knoevenagel Condensation/Lactonization Reaction of β‐Formyl‐esters and 1,3‐Cyclohexadiones.
Authors: Moghaddam Firouz Matloubi , Mirjafary Zohreh , Javan Marjan Jebeli , Motamen Sara , Saeidian Hamid 
Published: October 2014

AbstractThe title synthesis is advantageous with regards to operational simplicity, cheap starting materials, and moderate to high yields.
ChemInform Abstract: Synthesis of α,β‐Unsaturated Amides and Iminocoumarins from N,N‐Disulfonyl Ynamides with Aldehydes via the Ketenimine Intermediate.
Authors: Yu Lian , Cao Jian 
Published: October 2014

AbstractA novel synthesis of α,β‐unsaturated amides (III) from N,N‐disulfonyl ynamides (I) and aryl aldehydes (II) is developed.
ChemInform Abstract: Triphenylphosphine‐m‐sulfonate/Carbon Tetrabromide as an Easily Recoverable Catalyst System for the Efficient Synthesis of Xanthene and Xanthenone Derivatives under Solvent‐Free Conditions.
Authors: Huo Cong‐De , Bao Xia‐Zhen , Hu Dong‐Cheng , Jia Xiao‐Dong , Sun Chou‐Gu , Wang Cheng 
Published: October 2014

AbstractThe new and efficient catalyst system can be easily recovered and reused ten times without significant loss of activity.
ChemInform Abstract: Rh(III)‐Catalyzed Regioselective Hydroarylation of Alkynes via Directed C—H Functionalization of Pyridines.
Authors: Qian Zhen‐Chao , Zhou Jun , Li Bo , Hu Fang , Shi Bing‐Feng 
Published: October 2014

AbstractThis developed method tolerates a wide range of functional groups and is highly regioselective.
ChemInform Abstract: Reduction of 3‐Aminoquinoline‐2,4(1H,3H)‐diones and Deamination of the Reaction Products.
Authors: Klasek Antonin , Lycka Antonin , Rouchal Michal , Rudolf Ondrej , Ruzicka Ales 
Published: October 2014

AbstractReduction of the title aminoquinolinediones (I) with NaBH4 proceeds with excellent stereoselectivity furnishing cis‐3‐amino‐3,4‐dihydro‐4‐hydroxyquinolinones (II) in high yield.
ChemInform Abstract: A Rapid Entry to Amino Acid Derived Diverse 3,4‐Dihydropyrazines and Dihydro[1,2,3]triazolo[1,5‐a]pyrazines Through 1,3‐Dipolar Cycloaddition.
Authors: Bera Saurav , Panda Gautam 
Published: October 2014

AbstractA simple synthetic route to enantiomerically pure 5‐methyl‐3,4‐dihydropyrazines (VIII), triazolo[1,5‐a]pyrazines (II) and (IV) and triazolo[1,5‐a][1,4]diazocine (VI) starting from commercially available amino acids derived synthetic intermediates is described.
ChemInform Abstract: Acid‐Mediated Ring‐Expansion Reaction of N‐Aryl‐2‐vinylazetidines: Synthesis and Unanticipated Reactivity of Tetrahydrobenzazocines.
Authors: Shimizu Tomoaki , Koya Shunsuke , Yamasaki Ryu , Mutoh Yuichiro , Azumaya Isao , Katagiri Kosuke , Saito Shinichi 
Published: October 2014

AbstractIn the presence of 1.5 equivalents of H2SO4, vinylazetidines are found to undergo ring expansion to benzazocine derivatives like (II) which are unstable undergoing ring contraction to vinyltetrahydroquinolines (III) under slightly acidic conditions.
ChemInform Abstract: An Improved Synthesis of β‐Carboline and Azepino‐and Azocino[3,4‐b]indole Derivatives from Lactams.
Authors: Tokmakov G. P. 
Published: October 2014

AbstractThe title compounds (IV) are obtained by Vilsmeier formylation of lactams (I) followed by treatment with aryl hydrazines in one pot without isolating the intermediate α‐formyl lactams.
ChemInform Abstract: Palladium‐Catalyzed Air‐Based Oxidative Coupling of Arylboronic Acids with H‐Phosphine Oxides Leading to Aryl Phosphine Oxides.
Authors: Fu Tingting , Qiao Hongwei , Peng Zhimin , Hu Gaobo , Wu Xueji , Gao Yuxing , Zhao Yufen 
Published: October 2014

AbstractA novel methodology for the creating C—P bond via the oxidative coupling of a wide range of arylboronic acids with various H‐phosphine oxides in the presence of palladium catalyst under dry air as the green oxidant is described.
ChemInform Abstract: Three New Cucurbitane Triterpenoids from Hemsleya penxianensis and Their Cytotoxic Activities.
Authors: Xu Xiaoting , Bai Hong , Zhou Ling , Deng Zhipeng , Zhong Hao , Wu Zhongyu , Yao Qingqiang 
Published: October 2014

AbstractThree new cucurbitane glycosides, hemslepenside A (I), cucurbitacin F β‐D‐glucopyranoside (IIb), and cucurbitacin F (II) are isolated along with three known cucurbitane compounds from the roots of Hemsleya penxianensis.
ChemInform Abstract: Three New Diterpenoids from Leonurus japonicus
Authors: Liu Zhi‐Ke , Wu Da‐Rong , Shi Yi‐Ming , Zeng Ting , Liu Shao‐Hua , Du Xue , Dang Yong‐Jun , Xiao Wei‐Lie , Sun Han‐Dong 
Published: October 2014

Abstractisolation and structure elucidation
ChemInform Abstract: Regiocontrolled Palladium‐Catalyzed and Copper‐Mediated C—H Bond Functionalization of Protected L‐Histidine.
Authors: Mahindra Amit , Jain Rahul 
Published: October 2014

AbstractA variety of C‐2 arylated L‐histidine derivatives (III) are synthesized, which possess dual hydrophobic—hydrophilic character.
ChemInform Abstract: An Efficient and Simple Method for Stereoselective Synthesis of N‐Substituted Iminosugars from D‐Xylose Derivative.
Authors: Zhang Jichao , Yuan Wen , Ma Xiaofeng , Wang Haibo , Shao Huawu 
Published: October 2014

Abstract12 Iminosugars of type (IV) are prepared starting from D‐xylose derivative (I).
ChemInform Abstract: Bromopyrrole Alkaloids from a Marine Sponge Agelas sp.
Authors: Kusama Taishi , Tanaka Naonobu , Takahashi‐Nakaguchi Azusa , Gonoi Tohru , Fromont Jane , Kobayashi Jun'ichi 
Published: October 2014

AbstractFive new bromopyrrole alkaloids, 2‐bromokeramadine, 2‐bromo‐9,10‐dihydrokeramadine (II), tauroacidins C and D, and mukanadin G (II) are isolated together with three known bromopyrrole alkaloids.
ChemInform Abstract: Acyclic Sulfides, Garlicnins L‐1—L‐4, E, and F, from Allium sativum.
Authors: Nohara Toshihiro , Fujiwara Yukio , Ikeda Tsuyoshi , Yamaguchi Koki , Manabe Hideyuki , Murakami Kotaro , Ono Masateru , Nakano Daisuke , Kinjo Junei 
Published: October 2014

AbstractSix novel acyclic sulfides, named garlicnins L‐1 (I), L‐2, L‐3, L‐4 (II), E (III) and F are isolated which are able to suppress M2 macrophage activation.
ChemInform Abstract: Formamidobisabolene‐Based Derivatives from a Sponge Axinyssa sp.
Authors: Cheng Wei , Liu Dong , Zhang Fengying , Zhang Qingying , Pedpradab Patchara , Proksch Peter , Liang Hong , Lin Wenhan 
Published: October 2014

Abstract12 new formamidobisabolene derivatives, named axinyssines A‐L, are isolated from a Chinese sponge Axinyssa sp.
ChemInform Abstract: Perovskite Oxides: Preparation, Characterizations, and Applications in Heterogeneous Catalysis
Authors: Zhu Junjiang , Li Hailong , Zhong Linyun , Xiao Ping , Xu Xuelian , Yang Xiangguang , Zhao Zhen , Li Jinlin 
Published: October 2014

AbstractReview: 284 refs.
Variable detours in long‐distance migration across ecological barriers and their relation to habitat availability at ground
Authors: Hahn Steffen , Emmenegger Tamara , Lisovski Simeon , Amrhein Valentin , Zehtindjiev Pavel , Liechti Felix 
Published: October 2014

AbstractMigration detours, the spatial deviation from the shortest route, are a widespread phenomenon in migratory species, especially if barriers must be crossed. Moving longer distances causes additional efforts in energy and time, and to be adaptive, this should be counterbalanced by favorable condition en route. We compared migration patterns of nightingales that travelled along different flyways from their European breeding sites to the African nonbreeding sites. We tested for deviations from shortest routes and related the observed and expected routes to the habitat availability at ground during autumn and spring migration. All individuals flew detours of varying extent. Detours were largest and seasonally consistent in western flyway birds, whereas birds on the central and eastern flyways showed less detours during autumn migration, but large detours during spring migration (eastern flyway birds). Neither migration durations nor the time of arrival at destination were related to the lengths of detours. Arrival at the breeding site was nearly synchronous in birds flying different detours. Flying detours increased the potential availability of suitable broad‐scale habitats en route only along the western flyway. Habitat availability on observed routes remained similar or even decreased for individuals flying detours on the central or the eastern flyway as compared to shortest routes. Thus, broad‐scale habitat distribution may partially explain detour performance, but the weak detour‐habitat association along central and eastern flyways suggests that other factors shape detour extent regionally. Prime candidate factors are the distribution of small suitable habitat patches at local scale as well as winds specific for the region and altitude.
Spatiotemporal requirements for IRF7 in mediating type I IFN‐dependent susceptibility to blood‐stage Plasmodium infection
Authors: Edwards Chelsea L. , Best Shannon E. , Gun Sin Yee , Claser Carla , James Kylie R. , de Oca Marcela Montes , Sebina Ismail , Rivera Fabian de Labastida , Amante Fiona H. , Hertzog Paul J. , Engwerda Christian R. , Renia Laurent , Haque Ashraful 
Published: October 2014

Type I IFN signaling suppresses splenic T helper 1 (Th1) responses during blood‐stage Plasmodium berghei ANKA (PbA) infection in mice, and is crucial for mediating tissue accumulation of parasites and fatal cerebral symptoms via mechanisms that remain to be fully characterized. Interferon regulatory factor 7 (IRF7) is considered to be a master regulator of type I IFN responses. Here, we assessed IRF7 for its roles during lethal PbA infection and nonlethal Plasmodium chabaudi chabaudi AS (PcAS) infection as two distinct models of blood‐stage malaria. We found that IRF7 was not essential for tissue accumulation of parasites, cerebral symptoms, or brain pathology. Using timed administration of anti‐IFNAR1 mAb, we show that late IFNAR1 signaling promotes fatal disease via IRF7‐independent mechanisms. Despite this, IRF7 significantly impaired early splenic Th1 responses and limited control of parasitemia during PbA infection. Finally, IRF7 also suppressed antiparasitic immunity and Th1 responses during nonlethal PcAS infection. Together, our data support a model in which IRF7 suppresses antiparasitic immunity in the spleen, while IFNAR1‐mediated, but IRF7‐independent, signaling contributes to pathology in the brain during experimental blood‐stage malaria.
Experimental investigation on seismic behavior of scoured bridge pier with pile foundation
Authors: Wang Shiou‐Chun , Liu Kuang‐Yen , Chen Chia‐Han , Chang Kuo‐Chun 
Published: October 2014

SummaryThis study investigated the seismic performance and soil‐structure interaction of a scoured bridge models with pile foundation by shaking table tests using a biaxial laminar shear box. The bridge pier model with pile foundation comprised a lumped mass representing the superstructure, a steel pier, and a footing supported by a single aluminum pile within dry silica sand. End of the pile was fixed at the bottom of the shear box to simulate the scenario that the pile was embedded in a firm stratum of rock. The bridge pier model was subjected to one‐directional shakes, including white noise and earthquake records. The performance of the bridge pier model with pile foundation was discussed for different scoured conditions. It is found that the moment demand of pile increases with the increase of scoured depth whereas the moment demand of the bridge pier decreases, and this transition may induce the bridge failure mechanism transform from pier to pile. The seismic demand on scoured pile foundations may be underestimated and misinterpreted to a certain degree. When evaluating the system damping ratio with SSI, the system response may not be significantly changed even if the soil viscous damping contribution is varied. Copyright © 2014 John Wiley & Sons, Ltd.
Degraded EEG decoding of wrist movements in absence of kinaesthetic feedback
Authors: Galán Ferran , Baker Mark R. , Alter Kai , Baker Stuart N. 
Published: October 2014

AbstractA major assumption of brain–machine interface research is that patients with disconnected neural pathways can still volitionally recall precise motor commands that could be decoded for naturalistic prosthetic control. However, the disconnected condition of these patients also blocks kinaesthetic feedback from the periphery, which has been shown to regulate centrally generated output responsible for accurate motor control. Here, we tested how well motor commands are generated in the absence of kinaesthetic feedback by decoding hand movements from human scalp electroencephalography in three conditions: unimpaired movement, imagined movement, and movement attempted during temporary disconnection of peripheral afferent and efferent nerves by ischemic nerve block. Our results suggest that the recall of cortical motor commands is impoverished in the absence of kinaesthetic feedback, challenging the possibility of precise naturalistic cortical prosthetic control. Hum Brain Mapp 36:643–654, 2015. © 2014 The Authors. Human Brain Mapping Published by Wiley Periodicals, Inc.
Functional connectivity and neuronal variability of resting state activity in bipolar disorder—reduction and decoupling in anterior cortical midline structures
Authors: Magioncalda Paola , Martino Matteo , Conio Benedetta , Escelsior Andrea , Piaggio Niccolò , Presta Andrea , Marozzi Valentina , Rocchi Giulio , Anastasio Loris , Vassallo Linda , Ferri Francesca , Huang Zirui , Roccatagliata Luca , Pardini Matteo , Northoff Georg , Amore Mario 
Published: October 2014

AbstractIntroduction: The cortical midline structures seem to be involved in the modulation of different resting state networks, such as the default mode network (DMN) and salience network (SN). Alterations in these systems, in particular in the perigenual anterior cingulate cortex (PACC), seem to play a central role in bipolar disorder (BD). However, the exact role of the PACC, and its functional connections to other midline regions (within and outside DMN) still remains unclear in BD. Methods: We investigated functional connectivity (FC), standard deviation (SD, as a measure of neuronal variability) and their correlation in bipolar patients (n = 40) versus healthy controls (n = 40), in the PACC and in its connections in different frequency bands (standard: 0.01–0.10 Hz; Slow‐5: 0.01–0.027 Hz; Slow‐4: 0.027–0.073 Hz). Finally, we studied the correlations between FC alterations and clinical‐neuropsychological parameters and we explored whether subgroups of patients in different phases of the illness present different patterns of FC abnormalities. Results: We found in BD decreased FC (especially in Slow‐5) from the PACC to other regions located predominantly in the posterior DMN (such as the posterior cingulate cortex (PCC) and inferior temporal gyrus) and in the SN (such as the supragenual anterior cingulate cortex and ventrolateral prefrontal cortex). Second, we found in BD a decoupling between PACC‐based FC and variability in the various target regions (without alteration in variability itself). Finally, in our subgroups explorative analysis, we found a decrease in FC between the PACC and supragenual ACC (in depressive phase) and between the PACC and PCC (in manic phase). Conclusions: These findings suggest that in BD the communication, that is, information transfer, between the different cortical midline regions within the cingulate gyrus does not seem to work properly. This may result in dysbalance between different resting state networks like the DMN and SN. A deficit in the anterior DMN‐SN connectivity could lead to an abnormal shifting toward the DMN, while a deficit in the anterior DMN‐posterior DMN connectivity could lead to an abnormal shifting toward the SN, resulting in excessive focusing on internal contents and reduced transition from idea to action or in excessive focusing on external contents and increased transition from idea to action, respectively, which could represent central dimensions of depression and mania. If confirmed, they could represent diagnostic markers in BD. Hum Brain Mapp 36:666–682, 2015. © 2014 Wiley Periodicals, Inc.
The use of a combined respirometric–titrimetric setup to assess the effect of environmental conditions on micro‐algal growth rate
Authors: Decostere Bjorge , Van Hulle Stijn WH , Duyck Mathieu , Maere Thomas , Vervaeren Han , Nopens Ingmar 
Published: October 2014

AbstractBACKGROUNDOwing to their complexity a lot of research is performed on micro‐algal systems for wastewater treatment. In this work a previously developed combined respirometric–titrimetric approach was used for the determination of micro‐algal kinetics. A Plackett–Burman design with fold‐over was executed to investigate the influence of eight different degrees of freedom regarding environmental conditions on five different aspects (or responses) related to the micro‐algal photosynthetic activity.RESULTSResults revealed correlation between micro‐algal biomass concentration and both oxygen production rate and proton addition rate. When ammonium limiting conditions were implemented (molar N/P ratio = 7/1), a decrease of the titrimetric profile was observed. Regarding light intensity and temperature, no limitation was observed. Furthermore, with respect to inorganic phosphorus, no limitation was observed.CONCLUSIONSAlthough expected based on the literature, limitation was not observed for light intensity, temperature, and inorganic phosphorus, indicating that these state conditions were not limiting in the ranges applied in this research. Overall it can be concluded that the combined respirometric–titrimetric approach is successful for determination of limiting and non‐limiting components of wastewater nutrients and environmental conditions for micro‐algal growth. © 2014 Society of Chemical Industry
Efficient, scalable and economical preparation of tris(deuterium)‐ and 13C‐labelled N‐methyl‐N‐nitroso‐p‐toluenesulfonamide (Diazald®) and their conversion to labelled diazomethane
Authors: Shields Samuel W. J. , Manthorpe Jeffrey M. 
Published: October 2014

AbstractA method for the preparation of multi‐gramme quantities of N‐methyl‐d3‐N‐nitroso‐p‐toluenesulfonamide (Diazald‐d3) and N‐methyl‐13C‐N‐nitroso‐p‐toluenesulfonamide (Diazald‐13C) and their conversion to diazomethane‐d2 and diazomethane‐13C, respectively, is presented. This approach uses robust and reliable chemistry, and critically, employs readily commercially available and inexpensive methanol as the label source. Several reactions of labelled diazomethane are also reported, including alkene cyclopropanation, phenol methylation and α‐diazoketone formation, as well as deuterium scrambling in the preparation of diazomethane‐d2 and subsequent methyl esterification of benzoic acid.
Mode‐matching analysis and design of substrate integrated waveguide T‐junction diplexer and corner filter
Authors: Kordiboroujeni Zamzam , Bornemann Jens 
Published: October 2014

SummaryThe mode‐matching technique is deployed in this paper in order to analyze and design a substrate integrated waveguide (SIW) T‐junction diplexer in Ku‐band. The diplexer has bandwidths of 4.12% and 3.79% at 14.55 and 15.85 GHz, respectively. Also in Ku‐band, an SIW corner filter is analyzed and designed with the same technique. Analytical results are compared with simulated data obtained from commercially available field solvers such as CST Microwave Studio and ANSYS HFSS. Excellent agreement between analytical and simulated data is achieved. Copyright © 2014 John Wiley & Sons, Ltd.
The Legislative Response to PTSD in the United States (1989–2009): A Content Analysis
Authors: Purtle Jonathan 
Published: October 2014

AbstractAlthough knowledge about posttraumatic stress disorder (PTSD) has grown over the past 40 years, PTSD policy research is undeveloped. This gap in knowledge warrants attention because policy is among the most powerful tools to prevent and mitigate the effects of PTSD. This study provides a content analysis of all bills introduced in U.S. Congress that explicitly mentioned PTSD. All bills and bill sections mentioning PTSD were coded to create a legislative dataset. Bills that addressed traumatic stress, but did not mention PTSD, were also identified as a comparison group. One hundred sixty‐one PTSD explicit bills containing 382 sections of legislative text were identified, as were 43 traumatic stress, non‐PTSD bills containing 55 sections (the 2 categories were mutually exclusive). Compared to traumatic stress, non‐PTSD sections, PTSD explicit sections were far more likely to target military populations (23.6% vs. 91.4%) and combat exposures (14.5% vs. 91.4%). PTSD, as a discrete diagnostic entity, has been largely defined as a problem unique to combat exposure and military populations in federal legislation. Research is needed to understand knowledge and perceptions of PTSD among policy makers and the public to inform science‐based advocacy strategies that translate the full spectrum of PTSD research into policy.