bluuebunny/crossref_metadata_2025_split huggingface dataset:
Intergenerational transfer of blood pressure knowledge and screening: a school-based hypertension awareness program in Singapore
Authors: Lwin May O. , Malik Shelly , Chua Terrance S. J. , Chee Tek Siong , Tan Yong Seng 
Published: December 2014

Objective: This study aims to examine the efficacy of a hypertension awareness education program in Singapore in reaching out to a wider population of diverse racial and intergenerational cohorts by dispatching grade five children as information intermediaries to their immediate and extended family members. Method: After receiving structured instruction and training on blood pressure screening, students were requested to share knowledge gained in school with their family members at home and practice blood pressure measurement on family volunteers. We assessed pre- and post-program blood pressure knowledge change, attitude toward screening, and the diffusion of blood pressure information. One adult family member was also asked to complete a short survey at the program end. Results: A comparison of the students’ (final n = 3926) pre- and post-program survey data showed that knowledge and attitudes towards knowledge sharing improved after participating in the program. The post-program survey also revealed that students generally felt confident and displayed positive attitudes in performing blood pressure screening on family members. On average, each student practiced blood pressure measurement on 3.04 people. Female family members were more likely to be targeted for knowledge sharing and screening than male family members. The family members’ survey revealed positive attitudes towards screening, but family members were not confident about getting their measurements done regularly. Conclusion: The program met its objectives in raising the awareness of grade five children and provision of knowledge. It also met the larger objective of raising hypertension awareness in a wider population, especially those who otherwise might not directly receive health education and blood pressure screening.
A succinct rating scale for radiology report quality
Authors: Yang Chengwu , Kasales Claudia J , Ouyang Tao , Peterson Christine M , Sarwani Nabeel I , Tappouni Rafel , Bruno Michael 
Published: December 2014

Context: Poorly written radiology reports are common among residents and are a significant challenge for radiology education. While training may improve report quality, a professionally developed reliable and valid scale to measure report quality does not exist. Objectives: To develop a measurement tool for report quality, the quality of report scale, with rigorous validation through empirical data. Methods: A research team of an experienced psychometrician and six senior radiologists conducted qualitative and quantitative studies. Five items were identified for the quality of report scale, each measuring a distinct aspect of report quality. Two dedicated training sessions were designed and implemented to help residents generate high-quality reports. In a blinded fashion, the quality of report scale was applied to 804 randomly selected reports issued before (n = 403) and after (n = 401) training. Full-scale psychometrical assessments were implemented onto the quality of report scale’s item- and scale-scores from the reports. The quality of report scale scores were correlated with report professionalism and attendings’ preference and were compared pre-/post-training. Results: The quality of report scale showed sound psychometrical properties, with high validity and reliability. Reports with higher quality of report scale score were more professional and preferable by attendings. Training improved the quality of report scale score, empirically validating the quality of report scale further. Conclusion: While succinct and practitioner friendly, the quality of report scale is a reliable and valid measure of radiology report quality and has the potential to be easily adapted to other fields such as pathology, where similar training would be beneficial.
Day-case holmium laser enucleation of the prostate
Authors: Cynk Mark , Georgiadis Georgios , Moore Emily , Appleby Jonathan , Griffiths Richard , Hale Jemma 
Published: December 2014

In 2011 day-case prostate surgery was selected for financial incentives in the UK by the Department of Health Payment by Results (PbR) scheme, with a target of 30% of holmium laser enucleation of the prostate (HoLEP) procedures as day cases for 2011–2012, increasing to 90% within three years. The objective was to determine the feasibility and safety of day-case HoLEP. Patients and methods: All patients presenting to an experienced HoLEP surgeon and requiring prostatic surgery were considered for day-case HoLEP. We developed a four-hour postoperative discharge protocol with specialist urology nurse assessment and discharge. Results: Between April 2011 and March 2014, 188 patients (median age 74, range 48–92) were eligible for HoLEP surgery. Four patients did not undergo surgery, and 70 (38%) did not fit the day-case criteria. The remaining 114 (62%) were considered for day surgery, of which 91 (80%) were successful. There was one readmission with haematuria and blocked catheter, and two late readmissions with secondary bleeding. Conclusions: Day-case HoLEP is feasible and safe, even in patients with significant comorbidity. Our overall day-case rate of 49.5% exceeds the initial 30% target set by PbR, but suggests that the 90% target is overly optimistic.
Synovial Lipomatosis (Lipoma Arborescens) of the Knee
Authors: Malkoç Melih , Korkmaz Ozgur , Seker Ali , Isyar Mehmet , Oltulu Ismail , Yalcın Sercan , Mahirogulları Mahir 
Published: December 2014

Objectives: The goals of this retrospective study are to emphasize that the patients who have non surgical treatments for several times due to the massive swelling in their knees should be considered the SL and this pathology is treatable by arthroscopic synovectomy Methods: Seventeen patients (four female and thirteen male), were evaluated retrospectively from May 2009 and April 2013. Mean age for female group was 34,75 (range between 32 to 41) and for male group was 34,23 (range between 26 to 46). Mean follow-up period was 14,76 months (range between 6 months and 38 months). Mean duration of compliance was 26,23 months (range between 9 to 96) months. All patients rated by Knee Society Score preoperatively and postoperatively arthroscopic synovectomy, performed by using radiofrequency ablation and arthroscopic shaver for treatment procedure. Patients were discharged at the end of the one day hospitalization. Postoperatively all patients were allowed to full range of motion and full weight-bearing within one day after surgery. Results: Patients were evaluated preoperatively and postoperatively using the Knee Society Score. The mean Knee Society Score was 67,82 preoperatively and 88,23 was postoperatively. There is significant difference between preoperative and postoperative Knee Society scores.(p <0.05) At the end of the three months, MRI studied and there was no clue of recurrence except two patients. All patients returned to their daily activities with full of range of motion and without swelling of the affected knee joints. At the microscopic histological studies were reported as synovial lipomatosis for all patients Conclusion: Arthroscopic synovectomy is the safe and dramatically effective method of treatment in synovial lipomatosis with less complication, curability and retrieving patients full range of motion with no limitation in their daily activities
Unusual Iatrogenic Complication of ACL Surgery
Authors: Sargın Serdar , Atik Aziz , Meriç Gökhan , Aslan Ahmet 
Published: December 2014

Objectives: Anterior cruciate ligament (ACL) ruptures constitute the most common ligament injury of the knee, and ACL reconstruction is a commonly performed procedure in orthopedic sport medicine. We report a case of on-the-cartilage placement of EndoButton for ACL reconstruction and its treatment with arthroscopic removal. The rehabilitation method was successful, resulting in excellent function and range of motion of the knee. The aim of this study was present an unusual case of iatrogenic complication of ACL reconstruction and to highlight to the surgeons about this complication. Methods: A 22-year-old male patient administered to our outpatient clinic with a history of trauma to his left knee in a soccer game 2 years ago. He underwent arthroscopic transtibial ACL reconstruction using hamstring tendons and EB system in another facility 19 months ago. At the time of initial administration he complained about pain and friction on his left knee, especially when he was running. In his physical examination patellar friction, anterior drawer and lachman tests were pathological which reminded us rerupture of ACL. Knee movements were in normal limits, but he felt pain especially during flexion and extension. Results: We used standard anteromedial and anterolateral portals and an accessory portal for excision of EB. When we explored the knee arthroscopically, we observed the EB misplaced on femoral groove. Firstly the loop of EB was cut then the EB was removed from superolateral portal. Loop remnant was cauterized with RF probe. The knee was irrigated and portals were sutured. The operation was finished without complication. The knee was dressed and the patient was kept in an adjustable knee brace. There was no complaint of crepitation and the range of motion (ROM) of knee was in normal limits. We offered revision operation again but the patient didn’t accept this suggestion. Conclusion: EB is a good and a commonly used option in ACL reconstruction surgery. Even the complication rates seem much more acceptable when compared to other fixation methods; misplacement of fixation device can be seen. In such a situation it is believed that, surgeons must not hesitate for arthroscopic removal and revision surgery.
Jun-regulated genes promote interaction of diffuse large B-cell lymphoma with the microenvironment
Authors: Blonska Marzenna , Zhu Yifan , Chuang Hubert H. , You M. James , Kunkalla Kranthi , Vega Francisco , Lin Xin 
Published: December 2014

Key PointsElevated Jun signaling promotes lymphoma growth and dissemination to extranodal sites. Jun-regulated genes mediate the interaction of malignant cells with stromal cells and adhesion to extracellular matrix proteins.
The thrombopoietin receptor P106L mutation functionally separates receptor signaling activity from thrombopoietin homeostasis
Authors: Stockklausner Clemens , Klotter Anne-Christine , Dickemann Nicole , Kuhlee Isabelle N. , Duffert Christin M. , Kerber Carolin , Gehring Niels H. , Kulozik Andreas E. 
Published: December 2014

Key Points
The c-Mpl activity in downstream signaling and in platelet homeostasis can be functionally separated. The c-Mpl platelet homeostasis depends on correct processing and surface expression of the receptor, whereas downstream signaling does not.
Chronic and acute anemia and extracranial internal carotid stenosis are risk factors for silent cerebral infarcts in sickle cell anemia
Authors: Bernaudin Françoise , Verlhac Suzanne , Arnaud Cécile , Kamdem Annie , Vasile Manuela , Kasbi Florence , Hau Isabelle , Madhi Fouad , Fourmaux Christine , Biscardi Sandra , Epaud Ralph , Pondarré Corinne 
Published: December 2014

Key PointsBaseline hemoglobin levels lower than 7 g/dL, acute anemia, and extracranial internal carotid stenosis are significant and independent risk factors for SCI in SCA.
Antibiotics and extracorporeal circulation – one size does not fit all
Authors: Gonçalves-Pereira João , Oliveira Bruno 
Published: December 2014

AbstractDosing of antibiotics in critically ill patients is a significant challenge. The increasing number of patients undergoing extracorporeal membrane oxygenation further complicates the issue due to inflammatory activation and to drug sequestration in the circuit. Since patients receiving extracorporeal membrane oxygenation commonly face severe infections, appropriate antibiotic selection and correct dosing is of paramount importance to improve survival. Therapeutic drug monitoring (whenever available) or population pharmacokinetics, based on readily available clinical and laboratory data, should help tailor antibiotic dosing to the individual patient.
Dietary Exposure to the Endocrine Disruptor Tolylfluanid Promotes Global Metabolic Dysfunction in Male Mice
Authors: Regnier Shane M. , Kirkley Andrew G. , Ye Honggang , El-Hashani Essam , Zhang Xiaojie , Neel Brian A. , Kamau Wakanene , Thomas Celeste C. , Williams Ayanna K. , Hayes Emily T. , Massad Nicole L. , Johnson Daniel N. , Huang Lei , Zhang Chunling , Sargis Robert M. 
Published: December 2014

AbstractEnvironmental endocrine disruptors are implicated as putative contributors to the burgeoning metabolic disease epidemic. Tolylfluanid (TF) is a commonly detected fungicide in Europe, and previous in vitro and ex vivo work has identified it as a potent endocrine disruptor with the capacity to promote adipocyte differentiation and induce adipocytic insulin resistance, effects likely resulting from activation of glucocorticoid receptor signaling. The present study extends these findings to an in vivo mouse model of dietary TF exposure. After 12 weeks of consumption of a normal chow diet supplemented with 100 parts per million TF, mice exhibited increased body weight gain and an increase in total fat mass, with a specific augmentation in visceral adipose depots. This increased adipose accumulation is proposed to occur through a reduction in lipolytic and fatty acid oxidation gene expression. Dietary TF exposure induced glucose intolerance, insulin resistance, and metabolic inflexibility, while also disrupting diurnal rhythms of energy expenditure and food consumption. Adipose tissue endocrine function was also impaired with a reduction in serum adiponectin levels. Moreover, adipocytes from TF-exposed mice exhibited reduced insulin sensitivity, an effect likely mediated through a specific down-regulation of insulin receptor substrate-1 expression, mirroring effects of ex vivo TF exposure. Finally, gene set enrichment analysis revealed an increase in adipose glucocorticoid receptor signaling with TF treatment. Taken together, these findings identify TF as a novel in vivo endocrine disruptor and obesogen in mice, with dietary exposure leading to alterations in energy homeostasis that recapitulate many features of the metabolic syndrome.
Validation of several species names in Hyacinthaceae
Authors: Martínez-Azorín Mario , Crespo Manuel B. 
Published: December 2014

AbstractHyacinthaceae includes many taxa of hysteranthous or proteranthous plants, in which leaves and inflorescences are not coetaneous. Many herbarium sheets of such taxa, including type specimens, were prepared with samples gathered at different times to include as many vegetative and reproductive structures as possible to facilitate future identification. As a result of our taxonomic work being undertaken on several genera of the family, we found that holotypes of 14 taxa include different gatherings and are therefore not validly published, according to Art. 8.2 of the Melbourne Code. Validation of those names is effected in the same genera and ranks as they were first described, and a brief discussion is added for each case. Furthermore, four additional names are discussed in which a conclusive interpretation about invalid publication is not possible according to the available data, and hence their acceptance as valid names is here suggested.
Reestablishment ofCalyptrion(Violaceae)
Authors: de Paula-Souza Juliana , Pirani José Rubens 
Published: December 2014

AbstractRecent revisionary studies on the Neotropical lianescent genera of Violaceae revealed thatCalyptrionGing. is a validly published earlier name forCorynostylisMart., with species distributed in Amazonia and Central America. The species in the genus are reevaluated and four new combinations are effected,Calyptrion arboreum, C. carthagenense, C. pubescens, andC. volubile. Other nomenclatural issues, including typifications and synonymy, are also discussed.
Analytical evaluation of Diazyme procalcitonin (PCT) latex-enhanced immunoturbidimetric assay on Beckman Coulter AU5800
Authors: Dipalo Mariella , Buonocore Ruggero , Gnocchi Cecilia , Picanza Alessandra , Aloe Rosalia , Lippi Giuseppe 
Published: December 2014

AbstractThis study was aimed to evaluate the analytical performance of the novel Diazyme procalcitonin (PCT) immunoturbidimetric assay on Beckman Coulter AU5800.Diazyme PCT is a latex-enhanced immunoturbidimetric assay, developed for use on laboratory instrumentations with capability of reading absorbance at 600 nm. This analytical evaluation included the assessment of limit of blank (LOB), limit of detection (LOD), functional sensitivity, imprecision, linearity, carryover, and method comparison between Diazyme PCT and Kryptor PCT on 129 routine serum inpatient samples.The LOB, LOD, and functional sensitivity of Diazyme PCT were 0.16, 0.26, and 0.28 ng/mL, respectively. The intra- and inter-assay imprecision of Diazyme PCT was between 2.9% and 7.8%. The linearity was excellent in the range of PCT values between 0.16 and 56 ng/mL, and the carryover was negligible (0.02%). A highly significant agreement was found between Kryptor PCT and Diazyme PCT in a range of concentrations between 0.16 and 111 ng/mL (Diazyme PCT=1.10×Kryptor PCT–0.89; r=0.960; p<0.001). The mean bias was 0.48 ng/mL (95% CI, –0.58 to 1.54 ng/mL). The strength of agreement between Kryptor PCT and Diazyme PCT was between 85% and 96% at 0.50, 2.0, and 10 ng/mL cutoffs.Diazyme PCT appears to be a reliable assay for diagnosis and management of critical care patients susceptible to severe bacterial infections.
Nutrition intake and physical activity in a middle school in New York City
Authors: Gonzalez Marisol , Feinstein Ronald , Iezzi Carina , Fisher Martin 
Published: December 2014

Abstract
Purpose: The threat of childhood obesity has never been greater. Behavior changes implemented during childhood and adolescence are believed to be the most successful means of thwarting the progression of this epidemic. The American Academy of Pediatrics has developed a public health campaign that promotes awareness of clinical guidelines for nutrition and physical activity. The campaign is based on a concept developed by the Maine Center for Public Health referred to as “5-2-1-0 Healthy”. The simple clear message of this concept outlines steps families can take to help prevent and treat childhood obesity. The purpose of the present study is to determine the current level of compliance and health education needs of a middle school population related to the “5-2-1-0” concept.
Methods: A modified version of the 2010 National Youth Physical Activity and Nutrition Survey (developed by the Centers for Disease Control and Prevention) was distributed to students at a private, nonsectarian, middle school in New York City. The school is located in the borough of Manhattan, but includes youngsters from all five boroughs of the city. The questions were grouped and analyzed according to “5-2-1-0” categories. Surveys were scored, and the association between targeted questionnaire items and demographic variables (i.e., sex and grade) was examined.
Results: All 140 students completed the survey, and there was great variability in their responses to both the nutrition and physical activity questions. Of all students, 65% reported eating one cup or more of fruit daily, and 38% reported eating one cup or more of vegetables daily. There was no statistically significant difference reported in consumption of fruits or vegetables by gender or grade. Over 60% of students indicated <2 h of DVD/video or computer/video game time per day, while 10% indicated more than 3 h per day for each. A significant difference existed in the screen time reported between grades (more screen time by the older students) and a statistically significant difference also existed in the amount of physical activity reported by gender and grade (more physical activity by males and younger students). There was no difference in the reported consumption of sugar-sweetened beverages by gender or grade.
Conclusion: In a cohort of middle school students in New York City, there was great variability in compliance with the principles represented by the “5-2-1-0” concept. Changes in health behaviors were noted as students went from 6th to 7th to 8th grade, with physical activity decreasing and screen time increasing. Consequently, health curriculum topics for middle school students should focus on physical activity and screen time, while continuing to emphasize the need for proper nutrition.
Integral cross section measurements of a few threshold reactions induced by Am/Be neutrons
Authors: Uddin Md. Shuza , Spahn Ingo , Hossain Syed Mohammad , Rumman-Uz-Zaman Md. , Rakib-Uz-Zaman Md. , Qaim Syed M. 
Published: December 2014

Abstract
Integral cross sections of the reactions
46Ti(n, p)46Sc,
47Ti(n, p)47Sc,
48Ti(n, p)48Sc,
60Ni(n, p)60Co and
64Zn(n, p)64Cu were
measured with fast neutrons
(E

n
> 1.5MeV)
from an
Am/Be source. The results were compared with data
calculated using the neutron spectral distribution and the excitation
function of each reaction given in the data libraries ENDF/B-VII.0,
IRDF-2002, JEFF-3.2 and JENDL-4.0. In general, the integral
measurement and the integrated value agreed within ±4%,
except for the
46Ti(n, p)46Sc reaction where JEFF-3.2
shows a deviation of 7% and the
60Ni(n, p)60Co
reaction where ENDF/B-VII.0 and IRDF-2002 exhibit deviations upto
8%.
Revising the Law of the Mother in the Adoption-Marriage Plot
Authors: Murphy Gretchen 
Published: December 2014

Gretchen Murphy, “Revising the Law of the Mother in the Adoption-Marriage Plot” (pp. 342–365)
This essay traces a common plot in British and American fiction in which an outsider is first adopted and then later marries into a family. Such plots have been linked with the transition from blood to voluntary association in liberal society, but this essay examines the apparent superfluity of adoption and marriage in bringing the outsider into the family. Surveying historicist and psychoanalytic interpretations of the role of incest in the formation of democratic and contractual community in these works, the essay uses Juliet Mitchell’s psychoanalytic theory of siblings to propose that these plots address a central challenge of democracy: mediating equality and freedom when a legally imposed equality among all stands at odds with the freedom to create closed communities of choice. Shifting from adopted siblinghood to marriage enables a fantasy of social relations that are entirely chosen rather than imposed. Novels discussed include Jane Austen’s Mansfield Park (1814); James Fenimore Cooper’s Wyandotté (1843); Emily Brontë’s Wuthering Heights (1847); Maria Susanna Cummins’s The Lamplighter (1854); Frank J. Webb’s The Garies and Their Friends (1857); Anthony Trollope’s Doctor Thorne (1858); Harriet Beecher Stowe’s The Pearl of Orr’s Island (1862); Augusta Jane Evans’s St. Elmo (1866); María Ruiz de Burton’s Who Would Have Thought It? (1872); and Helen Hunt Jackson’s Ramona (1884).