bluuebunny/crossref_metadata_2025_split huggingface dataset:
Poor quality diet is associated with overweight status and obesity in patients with polycystic ovary syndrome
Authors: Rodrigues A. M. dos S. , Martins L. B. , Franklin A. M. T. , Candido A. L. , Santos L. C. dos , Ferreira A. V. M. 
Published: January 2014

AbstractBackgroundThe high rates of overweight status observed in women with polycystic ovary syndrome (PCOS) may reflect dietary intake, and so it is important to investigate diet quality and its relationship with the rates of overweight status and obesity among these patients.MethodsA cross‐sectional study was conducted in which 100 women with PCOS (Rotterdam criteria) were evaluated considering anthropometric and dietary data. The anthropometric evaluation included the measurement of weight, height, body mass index (BMI), waist circumference (WC), hip circumference and waist–hip ratio. Food intake data were collected from two 24‐h dietary recalls to assess dietary patterns using the Brazilian Healthy Eating Index – Revised (BHEI‐R).ResultsThe anthropometric analysis indicated a high prevalence of overweight status, obesity and increased visceral fat (30.0%, 60.0% and 90.0%, respectively). The mean BHEI‐R score was 56.1 ± 12.0 points (range 34.5–77.5 points). Diet quality was negatively correlated with obesity, which was evaluated by BMI (r = −0.248; P = 0.013) and WC (r = −0.278; P = 0.005).ConclusionsDietary interventions focused on improvement of diet quality should be targeted to treat patients with PCOS because obesity in these women is associated with worsening endocrine, metabolic and reproductive functions.
A systematic review and meta‐analysis of interventions for weight management using text messaging
Authors: Siopis G. , Chey T. , Allman‐Farinelli M. 
Published: January 2014

AbstractBackgroundObesity prevalence continues to increase worldwide, with significant associated chronic disease and health cost implications. Among more recent innovations in health service provision is the use of text messaging for health behaviour change interventions including weight management. This review investigates the efficacy of weight management programmes incorporating text messaging.MethodsMedical and scientific databases were searched from January 1993 to October 2013. Eligibility criteria included randomised controlled trials (RCTs), pseudoRCTs and before and after studies of weight management, among healthy children and adults, that used text messaging and included a nutrition component. Data extraction and quality assessment followed guidelines from PRISMA (Preferred Reporting Items for Systematic reviews and Meta‐Analyses) and the Evidence Analysis Manual of the American Academy of Nutrition and Dietetics.ResultsFrom 512 manuscripts retrieved, 14 met the inclusion criteria (five manuscripts in children and nine in adults). Duration of interventions ranged from 1 to 24 months. Frequency of text messaging was from daily to fortnightly. Six studies in adults were included in a meta‐analysis with mean body weight change as the primary outcome. The weighted mean change in body weight in intervention participants was −2.56 kg (95% confidence interval = −3.46 to −1.65) and in controls −0.37 kg (95% confidence interval = −1.22 to 0.48).ConclusionsThe small body of evidence indicates that text messaging interventions can promote weight loss. However, lack of long‐term results indicate that further efficacy studies are required. Future investigations should elucidate the determinants, such as intervention duration, text message frequency and level of interactivity that maximise the success and cost effectiveness of the delivery medium.
Interferon‐γ induces leucine‐rich repeat kinase LRRK2 via extracellular signal‐regulated kinase ERK5 in macrophages
Authors: Kuss Martin , Adamopoulou Eleni , Kahle Philipp J. 
Published: January 2014

AbstractThe gene encoding leucine‐rich repeat kinase 2 (LRRK2) comprises a major risk factor for Parkinson's disease. Recently, it has emerged that LRRK2 plays important roles in the immune system. LRRK2 is induced by interferon‐γ (IFN‐γ) in monocytes, but the signaling pathway is not known. Here, we show that IFN‐γ‐mediated induction of LRRK2 was suppressed by pharmacological inhibition and RNA interference of the extracellular signal‐regulated kinase 5 (ERK5). This was confirmed by LRRK2 immunostaining, which also revealed that the morphological responses to IFN‐γ were suppressed by ERK5 inhibitor treatment. Both human acute monocytic leukemia THP‐1 cells and human peripheral blood monocytes stimulated the ERK5‐LRRK2 pathway after differentiation into macrophages. Thus, LRRK2 is induced via a novel, ERK5‐dependent IFN‐γ signal transduction pathway, pointing to new functions of ERK5 and LRRK2 in human macrophages.
image
Leucine‐rich repeat kinase 2 (LRRK2) is a major risk factor for the development of Parkinson's disease (PD). However, the role of LRRK2 in the affected neurons remains enigmatic. Recently, LRRK2 has been reported to be strongly expressed in the immune system. Here, we demonstrate that LRRK2 is induced by Interferon gamma via extracellular signal‐regulated kinase 5 (ERK5) in macrophages, thus providing new insights in LRRK2 and ERK5 biology.
Effects of planned group interactions on the social adaptation of individuals with an intestinal stoma: a quantitative study
Authors: Karabulut Hatice K , Dinç Leyla , Karadag Ayişe 
Published: January 2014

Aims and objectivesTo investigate the effects of a planned group interaction method on the social adjustment of individuals with an intestinal stoma.BackgroundIndividuals with a stoma often experience physiological, psychological and social problems that affect their social adaptation.DesignQuasi‐experimental.MethodsThe population included ileostomy and colostomy patients registered at the Gazi University Health Research and Implementation Centre Stoma therapy Unit between September 2011–June 2012. They were assigned to experimental (n = 23) and control (n = 27) groups based on their willingness to attend planned group interaction meetings. Experimental group members participated in the ‘planned group interaction method’ for six weeks. Control group members only received routine care services. Weekly group interaction meetings lasted for average of 90 minutes. The Ostomy Adjustment Inventory and Psychosocial Adjustment to Illness Scale‐Self‐Report Scale were administered to experimental group members on three occasions: prior to the first group meeting, after the six‐week meeting process ended and during the first month after group meetings ended. Control group evaluations were conducted simultaneously.ResultsExperimental group members' ostomy adjustment mean scores after planned group interaction meetings gradually increased. No changes occurred in the control group's average scores. The experimental and control groups' average psychosocial adjustment scores eventually changed and showed a tendency towards adjustment. Experimental group members aged 51–60 and 61–70, who were married, had primary and higher education, had permanent stomas, had stomas for periods between 12 months or less and 61 months and longer and had sufficient stoma care knowledge demonstrated higher adjustment values (p < 0·05). Furthermore, experimental group members reported they received psychological support during interactions and learned how to solve problems encountered in stoma care and daily life.ConclusionsPlanned group interactions effectively enhanced the social adjustment of patients with a stoma.Relevance to clinical practiceGroup interaction methods should be included in nursing care practices for individuals with a stoma.
Effect of hospital case‐manager nurses on the level of dependence, satisfaction and caregiver burden in patients with complex chronic disease
Authors: García‐Fernández Francisco P , Arrabal‐Orpez María J , Rodríguez‐Torres María del Carmen , Gila‐Selas Carmen , Carrascosa‐García Isabel , Laguna‐Parras Juan M 
Published: January 2014

Aims and objectivesTo determine the medium‐term effects of nurse case management on the dependence and satisfaction of patients with complex chronic disease and on caregiver burden.BackgroundCaregiver exhaustion increases the readmission rate of highly dependent patients with complex chronic disease and their consumption of primary care resources.DesignAn observational and analytical cohort study was undertaken in multimorbid patients.MethodsData were gathered on Barthel Index and Caregiver Burden Index scores, primary care resource consumption, readmission and mortality rates, and patient satisfaction with care and care continuity. Results were compared between nurse case‐managed (n = 62) and control (n = 193) multimorbid patients using univariate and bivariate analyses.ResultsThe study included 255 patients with complex chronic disease (24·32% in management cohort vs. 75·68% in control cohort). The nurse case‐managed group had significantly lower Barthel Index and higher Caregiver Burden Index scores and a significantly longer hospital stay. At 90 days postdischarge, no significant intergroup differences were observed in Barthel Index or Caregiver Burden Index scores, primary care resource consumption, readmission rate or mortality rate; the case‐managed patients showed a significantly higher satisfaction level with their care and its continuity.ConclusionsNurse case management prevents a postdischarge increase in the dependence of multimorbid patients and the burden of their caregivers.Relevance to clinical practiceApplication of nurse case management can reduce the readmission rate and primary care consumption of patients with chronic complex disease after their hospital stay and prevent an exacerbation of caregiver exhaustion.
THEORY AND EVIDENCE IN PSYCHOLOGY AND ECONOMICS ABOUT MOTIVATION CROWDING OUT: A POSSIBLE CONVERGENCE?
Authors: Festré Agnès , Garrouste Pierre 
Published: January 2014

AbstractThe empirical relevance of motivation crowding out is a controversial issue in economics and psychology. As already pointed out by Frey and Jegen (), this is partly due to the historical development of two distinct and parallel strands of literature that stem from different theoretical traditions, have radically different tenets and therefore, are difficult to reconcile. In this survey, we go back to the details of the debates that took place independently among psychologists and economists, and sketch an integrative interdisciplinary approach likely to favor a more fruitful collaboration between economics and psychology. From this perspective, experimental economics (both field and laboratory) is viewed as a major research field shedding new light on the conditions of relevance of motivation crowding out.
The essential role of NGATHA genes in style and stigma specification is widely conserved across eudicots
Authors: Fourquin Chloé , Ferrándiz Cristina 
Published: January 2014

Summary

Carpel development and evolution are central issues for plant biology. The conservation of genetic functions conferring carpel identity has been widely studied in higher plants. However, although genetic networks directing the development of characteristic features of angiosperm carpels such as stigma and style are increasingly known in Arabidopsis thaliana, little information is available on the conservation and diversification of these networks in other species. Here, we have studied the functional conservation of NGATHA transcription factors in widely divergent species within the eudicots.

We determined by in situ hybridization the expression patterns of NGATHA orthologs in Eschscholzia californica and Nicotiana benthamiana. Virus‐induced gene silencing (VIGS)‐mediated inactivation of NGATHA genes in both species was performed and different microscopy techniques were used for phenotypic characterization.

We found the expression patterns of EcNGA and NbNGA genes during flower development to be highly similar to each other, as well as to those reported for Arabidopsis NGATHA genes. Inactivation of EcNGA and NbNGA also caused severe defects in style and stigma development in both species.

These results demonstrate the widely conserved essential role of NGATHA genes in style and stigma specification and suggest that the angiosperm‐specific NGATHA genes were likely recruited to direct a carpel‐specific developmental program.
Soluble phenylpropanoids are involved in the defense response of Arabidopsis against Verticillium longisporum
Authors: König Stefanie , Feussner Kirstin , Kaever Alexander , Landesfeind Manuel , Thurow Corinna , Karlovsky Petr , Gatz Christiane , Polle Andrea , Feussner Ivo 
Published: January 2014

Summary

Verticillium longisporum is a soil‐borne vascular pathogen causing economic loss in rape. Using the model plant Arabidopsis this study analyzed metabolic changes upon fungal infection in order to identify possible defense strategies of Brassicaceae against this fungus.

Metabolite fingerprinting identified infection‐induced metabolites derived from the phenylpropanoid pathway. Targeted analysis confirmed the accumulation of sinapoyl glucosides, coniferin, syringin and lignans in leaves from early stages of infection on. At later stages, the amounts of amino acids increased.

To test the contribution of the phenylpropanoid pathway, mutants in the pathway were analyzed. The sinapate‐deficient mutant fah1‐2 showed stronger infection symptoms than wild‐type plants, which is most likely due to the lack of sinapoyl esters. Moreover, the coniferin accumulating transgenic plant UGT72E2‐OE was less susceptible. Consistently, sinapoyl glucose, coniferyl alcohol and coniferin inhibited fungal growth and melanization in vitro, whereas sinapyl alcohol and syringin did not. The amount of lignin was not significantly altered supporting the notion that soluble derivatives of the phenylpropanoid pathway contribute to defense.

These data show that soluble phenylpropanoids are important for the defense response of Arabidopsis against V. longisporum and that metabolite fingerprinting is a valuable tool to identify infection‐relevant metabolic markers.
Compliance with Remote Monitoring of ICDS/CRTDS in a Real‐World Population
Authors: ROSENFELD LYNDA E. , PATEL AMISHA S. , AJMANI VIVEK B. , HOLBROOK REECE W. , BRAND TRINA A. 
Published: January 2014

BackgroundRemote monitoring (RM) of defibrillators (implantable cardioverter defibrillators [ICDs]) and cardiac resynchronization therapy devices (CRTDs) has been shown to be cost effective, convenient, and associated with reduced mortality and a reduction in the time to physician intervention for actionable events. However, patient compliance with monitoring over time and what factors might influence such compliance have not been well described. This study sought to identify factors contributing to patient noncompliance with RM of ICDs and CRTDs in a large real‐world population.MethodsDeidentified data on U.S. patients enrolled in the Medtronic CareLink RM system were used to compare patients with no (noncompliant, n = 14,848) and with ≥2 RM transmissions (compliant, n = 103,284) during a 14‐month period.ResultsOverall noncompliance with RM was 21%. Younger age (≤40), female sex, wanded device, Medicare Census Division, and small clinic size all predicted patient noncompliance (P < 0.01). Device type (ICD vs CRTD) did not (P = 0.52). Multivariate analysis suggested clinically important predictors of noncompliance to be: age ≤40, odds ratio (OR) 2.64 (95% confidence interval, 2.42–2.88); Medicare Census Division (Mountain vs West North Central), OR 2.15 (1.96–2.37); and small clinic size (1–4 vs >100 patients), OR 4.38 (3.92–4.91).ConclusionsThere is room for improvement in RM usage among enrolled patients. Younger patients, smaller clinics, and certain geographic areas may be targets for research into interventions to further improve the use of RM
Concentration, Activity and Biochemical Characterization of Myeloperoxidase in Fresh and Post‐Thaw Equine Semen and their Implication on Freezability
Authors: Ponthier J , Franck T , Parrilla‐Hernandez S , Niesten A , de la Rebiere G , Serteyn D , Deleuze S 
Published: January 2014

ContentsMyeloperoxidase (MPO) is a pro‐oxidant enzyme associated with decreased motility in thawed equine semen. This study aimed to describe MPO concentration, activity and subunits in raw and thawed semen and to correlate these data with motilities in raw and thawed semen. Semen samples from five stallions were collected four times. Motilities were assessed in raw and thawed semen. MPO assays were performed in raw seminal plasma, raw sperm‐rich pellet and thawed semen. Total and active MPO concentrations were, respectively, assayed by enzyme‐linked immunosorbent assay and specific immunological extraction followed by enzymatic detection. MPO subunits present in semen were characterized by Western blot. Purified active MPO was added in saline solution and freezing extender to control its activity during freezing procedure. Differences between medians were determined using Kruskal–Wallis test, and correlations were determined using Spearman's test for nonparametric data. Active MPO concentration was low in seminal plasma and thawed semen, but high in pellet (p = 0.0058), as the opposite relation was observed for total MPO concentration (p < 0.0001). In seminal plasma and post‐thaw semen, inactive 86‐kDa MPO precursor was mainly observed. Purified MPO activity was decreased in the extender (p = 0.0286). MPO activity in pellet was highly correlated with thawed progressive motility (r = −0.5576, p = 0.0086). Inactive MPO precursor and unknown low molecular weight inactive MPO precursor subunits explain low MPO activity in semen. Major MPO activity was observed in pellet, and post‐thaw loss of activity is partially explained by MPO inactivation in extender. Thawed semen motility was negatively correlated with MPO activity in pellet, becoming a potential freezability predictor.
Predicting the Parturition Date in Bitches of Different Body Weight by Ultrasonographic Measurements of Inner Chorionic Cavity Diameter and Biparietal Diameter
Authors: Socha P , Janowski T 
Published: January 2014

ContentsPredicting the parturition date in dogs by taking ultrasonographic foetometry has opened interesting research areas of veterinary obstetrics. Recently developed calculation formulas of inner chorionic cavity diameter (ICC) and biparietal diameter (BP) are formulas by Luvoni and Grioni (). This study is one of the first reports referring toICCandBPwith the use ofLuvoni andGrioni formulas for predicting the parturition time in dogs of different body weight in clinical practice conditions. The research material consists of 70 clinically healthy pregnant bitches of 27 breeds and cross‐breeds. Bitches were divided into 4 groups according to their body weight. In each of the bitches, ultrasonographic examination of pregnancy was performed at least twice (ICCandBPmeasurements). Parturition dates for dogs with a body weight over 25 kg were calculated based on formulas intended for the group of medium dogs. It was caused by the lack of appropriate formulas for these groups of dogs. The predicting parturition dates were compared with the actual dates of delivery provided by the bitch owners. Generally, the results obtained in this study are very encouraging and similar or even better than those published by other authors using foetometric measurements. In our research, when comparing the effectiveness of predicting the delivery date based on foetometric formulas by Luvoni and Grioni (), it was proved that in all groups of dogs, even those over 25 kg,ICCandBPmeasurements at both accuracy levels were characterized similar reliability.
Genome Sequence of an Alphabaculovirus Isolated from
Choristoneura murinana
Authors: Rohrmann George F. , Erlandson Martin A. , Theilmann David A. 
Published: January 2014

ABSTRACT

The genome sequence of a baculovirus from
Choristoneura murinana
is 124,689 bp, with a G+C content of 50%, and contains 148 putative open reading frames. The virus is a member of the group I alphabaculoviruses and is most closely related to several other viruses that infect
Choristoneura
species.
Complete Genome Sequence of Ehrlichia muris Strain AS145
T
, a Model Monocytotropic
Ehrlichia
Strain
Authors: Thirumalapura Nagaraja R. , Qin Xiang , Kuriakose Jeeba A. , Walker David H. 
Published: January 2014

ABSTRACT

We report here the complete genome sequence of
Ehrlichia muris
strain AS145
T
, which was isolated from a wild mouse in 1983 in Japan.
E. muris
establishes persistent infections in laboratory mice and is widely used as a surrogate pathogen in a murine model of ehrlichiosis.
Complete Genome Sequence of
Pseudomonas
sp. Strain TKP, Isolated from a γ-Hexachlorocyclohexane-Degrading Mixed Culture
Authors: Ohtsubo Yoshiyuki , Kishida Kouhei , Sato Takuya , Tabata Michiro , Kawasumi Toru , Ogura Yoshitoshi , Hayashi Tetsuya , Tsuda Masataka , Nagata Yuji 
Published: January 2014

ABSTRACT

Pseudomonas
sp. strain TKP does not degrade γ-hexachlorocyclohexane (γ-HCH), but it persistently coexists with the γ-HCH-degrading
Sphingobium
sp. strain TKS in a mixed culture enriched by γ-HCH. Here, we report the complete genome sequence of strain TKP, which consists of one circular chromosome with a size of 7 Mb.
F1 and Tbilisi Are Closely Related Brucellaphages Exhibiting Some Distinct Nucleotide Variations Which Determine the Host Specificity
Authors: Hammerl Jens A. , Al Dahouk Sascha , Nöckler Karsten , Göllner Cornelia , Appel Bernd , Hertwig Stefan 
Published: January 2014

ABSTRACT

We report on the 41,143-bp genome of brucellaphage F1, a podovirus that infects several
Brucella
species. The F1 genome is almost identical to the genome of brucellaphage Tb. However, some structural proteins of the phages exhibit extensive polymorphisms and might be responsible for their different host ranges.
Draft Genome Sequences of Three Alkaliphilic
Bacillus
Strains, Bacillus wakoensis JCM 9140
T
, Bacillus akibai JCM 9157
T
, and Bacillus hemicellulosilyticus JCM 9152
T
Authors: Yuki Masahiro , Oshima Kenshiro , Suda Wataru , Oshida Yumi , Kitamura Keiko , Iida Toshiya , Hattori Masahira , Ohkuma Moriya 
Published: January 2014

ABSTRACT

Here, we report the draft genome sequences of the type strains of three cellulolytic or hemicellulolytic alkaliphilic
Bacillus
species:
Bacillus wakoensis
,
Bacillus akibai
, and
Bacillus hemicellulosilyticus
. The genome information for these three strains will be useful for studies of alkaliphilic
Bacillus
species, their evolution, and biotechnological applications for their enzymes.
Draft Genome Sequence of Pseudomonas nitroreducens Strain TX1, Which Degrades Nonionic Surfactants and Estrogen-Like Alkylphenols
Authors: Huang Shir-Ly , Chen Hsin , Hu Anyi , Tuan Nguyen Ngoc , Yu Chang-Ping 
Published: January 2014

ABSTRACT

Pseudomonas nitroreducens
TX1 ATCC PTA-6168 was isolated from rice field drainage in Taiwan. The bacterium is of special interest because of its capability to use nonionic surfactants (alkylphenol polyethoxylates) and estrogen-like compounds (4-
t
-octylphenol and 4-nonylphenol) as a sole carbon source. This is the first report on the genome sequence of
P. nitroreducens
.
Draft Genome Sequence of a Mycobacterium avium Complex Isolate from a Broadbill Bird
Authors: Bannantine John P. , Bayles Darrell O. , Robbe-Austerman Suelee , Burrell Angela M. , Stabel Judith R. 
Published: January 2014

ABSTRACT

We report the draft genome sequence of a
Mycobacterium avium
complex isolate. This isolate has an estimated genome size of 5.1 Mb with an average GC content of 68.9% and is predicted to carry 4,497 protein-encoding genes and 317 pseudogenes.