bluuebunny/crossref_metadata_2025_split huggingface dataset:
An analysis of entorhinal cortex projections to the dentate gyrus, hippocampus, and subiculum of the neonatal macaque monkey
Authors: Amaral David G. , Kondo Hideki , Lavenex Pierre 
Published: October 2013

ABSTRACTThe entorhinal cortex is the primary interface between the hippocampal formation and neocortical sources of sensory information. Although much is known about the cells of origin, termination patterns, and topography of the entorhinal projections to other fields of the adult hippocampal formation, very little is known about the development of these pathways, particularly in the human or nonhuman primate. We have carried out experiments in which the anterograde tracers 3H‐amino acids, biotinylated dextran amine, and Phaseolus vulgaris leucoagglutinin were injected into the entorhinal cortex in 2‐week‐old rhesus monkeys (Macaca mulatta). We found that the three fiber bundles originating from the entorhinal cortex (the perforant path, the alvear pathway, and the commissural connection) are all established by 2 weeks of age. Fundamental features of the laminar and topographic distribution of these pathways are also similar to those in adults. There is evidence, however, that some of these projections may be more extensive in the neonate than in the mature brain. The homotopic commissural projections from the entorhinal cortex, for example, originate from a larger region within the entorhinal cortex and terminate much more densely in layer I of the contralateral entorhinal cortex than in the adult. These findings indicate that the overall topographical organization of the main cortical afferent pathways to the dentate gyrus and hippocampus are established by birth. These findings add to the growing body of literature on the development of the primate hippocampal formation and will facilitate further investigations on the development of episodic memory. J. Comp. Neurol. 522:1485–1505, 2014. © 2013 Wiley Periodicals, Inc.
Preprodynorphin‐expressing neurons constitute a large subgroup of somatostatin‐expressing GABAergic interneurons in the mouse neocortex
Authors: Sohn Jaerin , Hioki Hiroyuki , Okamoto Shinichiro , Kaneko Takeshi 
Published: October 2013

ABSTRACTDynorphins, leumorphin, and neoendorphins are preprodynorphin (PPD)‐derived peptides and ligands for κ‐opioid receptors. Using an antibody to PPD C‐terminal, we investigated the chemical and molecular characteristics of PPD‐expressing neurons in mouse neocortex. PPD‐immunopositive neuronal somata were distributed most frequently in layer 5 and less frequently in layers 2–4 and 6 throughout neocortical regions. Combined labeling of immunofluorescence and fluorescent mRNA signals revealed that almost all PPD‐immunopositive neurons expressed glutamic acid decarboxylase but not vesicular glutamate transporter, indicating their γ‐aminobutyric acid (GABA)ergic characteristics, and that PPD‐immunopositive neurons accounted for 15% of GABAergic interneurons in the primary somatosensory area. As GABAergic interneurons were divided into several groups by specific markers, we further examined the chemical characteristics of PPD‐expressing neurons by the double immunofluorescence labeling method. More than 95% of PPD‐immunopositive neurons were also somatostatin (SOM)‐immunopositive in the primary somatosensory, primary motor, orbitofrontal, and primary visual areas, but only 24% were SOM‐immunopositive in the medial prefrontal cortex. In the primary somatosensory area, PPD‐immunopositive neurons constituted 50%, 79%, 55%, and 17% of SOM‐immunopositive neurons in layers 2–3, 4, 5, and 6, respectively. Although SOM‐expressing neurons contained calretinin‐, neuropeptide Y‐, nitric oxide synthase‐, and reelin‐expressing neurons as subgroups, only reelin immunoreactivity was detected in many PPD‐immunopositive neurons. These results indicate that PPD‐expressing neurons constitute a large subgroup of SOM‐expressing cortical interneurons, and the PPD/SOM‐expressing GABAergic neurons might serve not only as inhibitory elements in the local cortical circuit, but also as modulators for cortical neurons expressing κ‐opioid and/or SOM receptors. J. Comp. Neurol. 522:1506–1526, 2014. © 2013 Wiley Periodicals, Inc.
Numerical investigation of biomagnetic fluids in circular ducts
Authors: Tzirakis K. , Papaharilaou Y. , Giordano D. , Ekaterinaris J. 
Published: October 2013

SUMMARYA mathematical model for the description of biomagnetic fluid flow exposed to a magnetic field that accounts for both electric and magnetic properties of the biofluid is presented. This is achieved by adding the Lorentz and magnetization forces in the Navier‐Stokes equations. To demonstrate the effects of magnetic fields, we consider the case of laminar, incompressible, viscous, the steady flow of a Newtonian biomagnetic fluid (i) between two parallel plates; and (ii) through a straight rigid tube with a 60% in diameter, 84% on area, axisymmetric stenosis. Two external magnetic fields were investigated: one produced by an infinite wire carrying constant current, and a dipole‐like field. We show, numerically and analytically, that the wire produces an irrotational force that, independent of its intensity, only alters the pressure leaving the velocity field unaffected. In contrast, when the fluid is exposed to the dipole‐like field, which generates a rotational force, then both pressure and velocity can be strongly influenced even at moderate field strengths. Similar trends were obtained when a time varying flow is simulated through the axisymmetric stenosis in the presence of the dipole‐like rotational magnetic field. It is expected that our findings could have important applications in blood flow control. Copyright © 2013 John Wiley & Sons, Ltd.
Evaluation of performance of various color‐difference formulae using an experimental black dataset
Authors: Shamey Renzo , Lin Juan , Sawatwarakul Weethima , Cao Renbo 
Published: October 2013

AbstractThe objective of this study was to develop a specific visual dataset comprising black‐appearing samples with low lightness (L* ranging from approximately 10.4 to 19.5), varying in hue and chroma, evaluating their visual differences against a reference sample, and testing the performance of major color difference formulas currently in use as well as OSA‐UCS‐based models and more recent CAM02 color difference formulas including CAM02‐SCD and CAM02‐UCS models. The dataset comprised 50 dyed black fabric samples of similar structure, and a standard (L*= 15.33, a* = 0.14, b* = −0.82), with a distribution of small color differences, in ΔE*ab, from 0 to approximately 5. The visual color difference between each sample and the standard was assessed by 19 observers in three separate sittings with an interval of at least 24 hours between trials using an AATCC standard gray scale for color change, and a total of 2850 assessments were obtained. A third‐degree polynomial equation was used to convert gray scale ratings to visual differences. The Standard Residual Sum of Squares index (STRESS) and Pearson's correlation coefficient (r), were used to evaluate the performance of various color difference formulae based on visual results. According to the analysis of STRESS index and correlation coefficient results CAM02 color difference equations exhibited the best agreement against visual data with statistically significant improvement over other models tested. The CIEDE2000 (1:1:1) equation also showed good performance in this region of the color space. © 2013 Wiley Periodicals, Inc. Col Res Appl, 39, 589–598, 2014
Toward the soft metrology of surface gloss: A review
Authors: Leloup Frédéric B. , Obein Gael , Pointer Michael R. , Hanselaer Peter 
Published: October 2013

AbstractThe most straightforward way to assess the glossiness of a surface is by measuring the specular reflectance by use of a specular glossmeter. Although alternative measurement methods have been proposed, this is still the most frequently used instrumental measurement technique for gloss evaluation until today. However, due to both the multidimensional nature of gloss perception and to the initial purpose of a specular glossmeter only to judge the gloss differences of surfaces with similar appearance, specular glossmeter results do not seem to provide a reliable basis for estimating the gloss appearance of a surface. During the past decades, increased attention has been paid to understanding how the human visual system arrives at a particular sensation of surface gloss, and which factors influence this process. This article was established in response to these new insights, and provides the reader an overview of the most important developments and findings regarding gloss measurement and gloss perception over the past 15 years. With the ultimate goal to achieve a better correspondence between gloss measurement and gloss perception in the future, issues of alternative measurement methods are considered, and some suggestions for relevant future research are proposed. © 2013 Wiley Periodicals, Inc. Col Res Appl, 39, 559–570, 2014
No influence of the CYP2C19‐selective inhibitor omeprazole on the pharmacokinetics of the dopamine receptor agonist rotigotine
Authors: Elshoff Jan‐Peer , Cawello Willi , Andreas Jens‐Otto , Braun Marina 
Published: October 2013

AbstractRotigotine, a non‐ergolinic dopamine receptor agonist administered transdermally via a patch, is metabolized by several cytochrome P‐450 (CYP450) isoenzymes, including CYP2C19. This open‐label, multiple‐dose study evaluated the effect of omeprazole, a competitive inhibitor of CYP2C19, on the pharmacokinetics of rotigotine and its metabolites under steady‐state conditions in healthy male subjects (of the extensive metabolizer phenotype, CYP2C19). Subjects received rotigotine 2 mg/24 hours on days 1–3, 4 mg/24 hours on days 4–12, and omeprazole 40 mg once daily on days 7–12 immediately after patch application. Blood and urine samples were collected on days 6 and 12 to evaluate rotigotine pharmacokinetic parameters alone and in the presence of omeprazole. Data from 37 subjects were available for pharmacokinetic analysis. Point estimates (90% confidence intervals, CI) for the ratios of AUC(0–24)SS and Cmax,SS of unconjugated rotigotine for the comparison rotigotine + omeprazole:rotigotine alone were close to 1 (0.9853 [0.9024, 1.0757] for AUC(0–24)SS and 1.0613 [0.9723, 1.1585] for Cmax,SS) with 90% CIs within the acceptance range for bioequivalence (0.80, 1.25). Selective inhibition of CYP2C19 by omeprazole did not alter the steady‐state pharmacokinetic profile of rotigotine or its metabolites. Thus, rotigotine dose adjustment is not required in patients receiving omeprazole, or other CYP2C19 inhibitors.
Wireless sensor network with energy harvesting: modeling and simulation based on a practical architecture using real radiation levels
Authors: Climent S. , Sanchez A. , Blanc S. , Capella J. V. , Ors R. 
Published: October 2013

SummaryThis paper presents a new energy‐harvesting model for a network simulator that implements super‐capacitor energy storage with solar energy‐harvesting recharge. The model is easily extensible, and other energy‐harvesting systems, or different energy storages, can be further developed. Moreover, code can be conveniently reused as the implementation is entirely uncoupled from the radio and node models. Real radiation data are obtained from available online databases in order to dynamically calculate super‐capacitor charge and discharge. Such novelty enables the evaluation of energy evolution on a network of sensor nodes at various physical world locations and during different seasons. The model is validated against a real and fully working prototype, and good result correlation is shown. Furthermore, various experiments using the ns‐3 simulator were conducted, demonstrating the utility of the model in assisting the research and development of the deployment of everlasting wireless sensor networks. Copyright © 2013 John Wiley & Sons, Ltd.
Cyclodextrin‐Based Ionic Liquids as Enantioselective Stationary Phases in Gas Chromatography
Authors: Costa Nuno , Matos Sara , Gomes da Silva Marco D. R. , Pereira M. Manuela A. 
Published: October 2013

AbstractNew permethylated mono‐6‐deoxy‐6‐pyridin‐1‐ium and mono‐6‐deoxy‐6‐(1‐vinyl‐1H‐imidazol‐3‐ium)‐α‐ and ‐β‐cyclodextrin trifluoromethanesulfonate ionic liquids were synthesized from the corresponding permethylated mono‐6‐hydroxycyclodextrins in a one‐pot reaction and solvent‐free procedure. Regioselective transformation of native α‐ and β‐cyclodextrins with the use of a bulky tert‐butyldiphenylsilyl protecting group afforded the desired 6‐monosubstituted permethylated cyclodextrin derivatives in moderate yields. The new ionic liquids were tested as stationary phases in capillary GC columns towards chiral discrimination in enantio‐GC analysis of racemic mixtures. The permethylated 6‐deoxy‐6‐pyridin‐1‐ium‐α‐cyclodextrin trifluoromethanesulfonate displayed good enantiomeric separations for some racemic esters and lactones, as well as epoxides. In particular, for both the racemic whiskey lactone and the high boiling point menthyl laurate, not successfully separated in a commercial cyclodextrin phase, the enantiomeric separations were achieved isothermally at 140 °C.
Highly Efficient Povidone–Phosphotungstic Acid Catalyst for the Tandem Acetalization of Aldehydes to Bis‐ and Tris(indolyl)methanes
Authors: Kamble Sumit B. , Swami Rameshwar K. , Sakate Sachin S. , Rode Chandrashekhar V. 
Published: October 2013

AbstractA novel, nonleachable hybrid of heteropoly acid and polyvinylpyrrolidone (or povidone) catalyzes the acetalization of aldehydes in methanol at room temperature followed by reaction with indole to give bis(indolyl)methanes (BIMs) and tris(indolyl)methanes (TIMs) in quantitative yields (90–97 %). The catalyst was shown by pyridine FTIR spectroscopy to possess Brønsted acidity, and the hybrid formation was confirmed by XRD and 31P NMR studies. Friedel–Crafts alkylation of indole as well as the tandem synthesis of BIMs and TIMs were established with several types of carbonyl and indole substrates to give the corresponding products quantitatively. The catalyst was recycled efficiently for three successive runs without losing its original activity.
Attribution of Somatic Symptoms in Hypochondriasis
Authors: Neng Julia M. B. , Weck Florian 
Published: October 2013

The misinterpretation of bodily symptoms as an indicator of a serious illness is a key feature of the criteria and the cognitive–behavioural models of hypochondriasis. Previous research suggests that individuals suffering from health anxiety endorse attributions of physical disease, whereas persons with elevated general anxiety have the tendency to attribute psychological causes to their symptoms. However, whether a somatic attribution style is specific to patients with hypochondriasis, as opposed to those with anxiety disorders, has not yet been investigated and is therefore part of the present study. Fifty patients with hypochondriasis, 50 patients with a primary anxiety disorder and 50 healthy participants were presented with nine common bodily sensations and had to spontaneously attribute possible causes to the symptoms. Patients with hypochondriasis differed from patients with anxiety disorders and healthy controls in giving significantly fewer normalizing explanations, but attributing more often in terms of moderate or serious diseases. Patients with anxiety disorders also made significantly fewer normalizing attributions and more somatic attributions to a severe illness than healthy controls. There were no differences between the groups in the frequency of psychological attributions and somatic attributions concerning mild diseases. The present study demonstrates that hypochondriasis is associated with a disorder‐specific attribution style connecting somatic symptoms primarily with moderate and serious diseases. By contrast, normalizing attributions are largely omitted from consideration by patients with hypochondriasis. The findings conform with the cognitive conception of hypochondriasis and support the strategy of modifying symptom attributions, as practiced in cognitive–behavioural therapy. Copyright © 2013 John Wiley & Sons, Ltd.Key Practitioner Message

Patients with hypochondriasis show a disorder‐specific attribution style, which is biased towards moderate and serious diseases.
This finding stresses the importance of therapeutic interventions challenging dysfunctional symptom attributions.
In addition to attributions in terms of moderate and serious diseases, patients with hypochondriasis also produce constructive attributions (normalizing, psychological or in terms of mild illnesses).
Therefore, particular emphasis should be placed on a comprehensive exploration of all existing symptom attributions. By identifying beneficial attributions already in existence, the patient's resources are brought into focus and form the basis for reattribution training.
A Dication Cross‐Linked Composite Anion‐Exchange Membrane for All‐Vanadium Flow Battery Applications
Authors: Zhang Fengxiang , Zhang Huamin , Qu Chao 
Published: October 2013

AbstractWe report the fabrication and properties of a high‐performance, inexpensive, composite, anion‐exchange membrane (AEM) for an all‐vanadium flow battery (VFB) application. The AEM was fabricated by dication cross‐linking without the involvement of trimethylamine, and shows well‐balanced anion conductivity and robustness due to imidazolium and imidazolium–ammonium functionalities, as well as a concomitantly achieved semi‐interpenetrating network structure. The VFB single cell yielded a Coulombic efficiency of 99 % and an energy efficiency of 84 % at 80 mA cm−2, and operated for over 900 charge/discharge cycles. This work demonstrates the combined use of several favorable AEM design rationales, such as incorporating abundant and efficient anion‐exchange groups, constructing a swelling‐ and oxidation‐resistant structure, and facile fabrication; it provides an effective way of developing high‐performance, low‐cost AEMs for VFB applications.
A 128‐channel discrete cosine transform‐based neural signal processor for implantable neural recording microsystems
Authors: Hosseini‐Nejad Hossein , Jannesari Abumoslem , Sodagar Amir M. , Rodrigues Joachim Neves 
Published: October 2013

AbstractA 128‐channel neural signal processor for implantable neural recording microsystems is presented. The processor compresses the neural information of 128 simultaneous recording channels using discrete cosine transform, achieving a compression factor of 69 at the expense of a 5.6% root mean square error. The proposed processor is implemented on register transfer level and synthesized in a 65‐nm complementary metal‐oxide semiconductor process. The post‐layout simulated power consumption at 1.2 V is 33.06 μW (258 nW per channel) at an area cost of 0.46 mm2. Copyright © 2013 John Wiley & Sons, Ltd.
An amplify‐and‐forward and decode‐and‐forward mixed relay communication system and its performance analysis
Authors: Guan Z.‐J. , Zhou X.‐L. 
Published: October 2013

SUMMARYA kind of amplify‐and‐forward (AF) and decode‐and‐forward (DF) mixed relay communication system is proposed in this letter. The source broadcasts the signal to all the relays. Relays that can decode the signal adopt DF scheme to retransmit the signal, while the rest adopt AF scheme for retransmission. The destination employs maximum ratio combining technique to maximize the received signal‐to‐noise ratio. Another situation concerned in this letter is that when the relay cannot decode the source signal, it may retransmit the interference signal with AF scheme. Closed‐form expressions of outage probability are derived. Simulation results show that the analytical curves agree with the simulated ones very well, and the AF‐DF mixed relay system can improve the availability of the relays. Copyright © 2013 John Wiley & Sons, Ltd.
Recursive‐clustering‐based approach for denial of service (DoS) attacks in wireless sensors networks
Authors: Fouchal S. , Mansouri D. , Mokdad L. , Iouallalen M. 
Published: October 2013

SUMMARYThis paper presents a novel approach for detecting denial of service attacks. In particular, the concern is on the sleeping deprivation attacks such as the malicious nodes that use flooding technique. Our approach is based on wireless sensor network (WSN) clustering. It consists in recursively clustering sensors until a required granularity (chosen by the expert) is achieved. We apply our approach with two different clustering algorithms. Indeed, we use the common clustering WSN algorithm Low Energy Algorithm Adaptive Clustering Hierarchy and the general clustering method Fast and Flexible Unsupervised Clustering Algorithm (FFUCA) based on ultrametric properties. We discuss the behavior of the approach with the two algorithms. Also, we present numerical results that show the efficiency of recursive clustering using the FFUCA algorithm. Copyright © 2013 John Wiley & Sons, Ltd.
A joint resource optimization and adaptive modulation framework for uplink single‐carrier frequency‐division multiple access systems
Authors: Ahmad Ayaz , Shah Nadir 
Published: October 2013

SummaryIn this paper, we study joint resource allocation and adaptive modulation in single‐carrier frequency‐division multiple access systems, which is adopted as the multiple access scheme for the uplink in the 3GPP Long Term Evolution standard. We formulate an adaptive modulation and sum‐cost minimization (JAMSCmin) problem. Unlike orthogonal frequency‐division multiple access, in addition to the restriction of allocating a subchannel to one user at most, the multiple subchannels allocated to a user in single‐carrier frequency‐division multiple access systems should be consecutive as well. This renders the resource allocation problem prohibitively difficult and the standard optimization tools (e.g., Lagrange dual approach widely used for orthogonal frequency‐division multiple access, etc.) cannot help towards its optimal solution. We propose a novel optimization framework for the solution of this problem that is inspired from the recently developed canonical duality theory. We first formulate the optimization problem as binary‐integer programming (BIP) problem and then transform this BIP problem into continuous space canonical dual problem that is the concave maximization problem. Based on the solution of the canonical dual problem, we derive joint resource allocation and adaptive modulation algorithm, which has polynomial time complexity. We provide conditions under which the proposed algorithm is optimal. We compare the proposed algorithm with the existing algorithms in the literature. The results show a tremendous performance gain. Copyright © 2013 John Wiley & Sons, Ltd.
Experiences with SoftToken: a token‐based coordination layer for WLANs
Authors: Eznarriaga Lucas , Senguly Cigdem , Bayer Nico , Moreno José Ignacio , Lozano Patricia , Simón María 
Published: October 2013

SummaryThis paper presents our experiences with SoftToken protocol, a new contention‐free medium access control protocol for wireless local area network. This new mechanism adds a token‐passing procedure on top of Institute of Electrical and Electronics Engineers 802.11 for coordinating transmissions and avoiding collisions. With this extension, it becomes possible to offer differentiated services in a deterministic manner. In this paper, we provide a thorough performance evaluation of SoftToken in terms of its scalability, robustness and efficiency in comparison with Institute of Electrical and Electronics Engineers 802.11 and a time division multiple access (TDMA)‐based Wi‐Fi extension called Soft‐TDMA. Our evaluation is based on experiments run on different test beds covering different scenarios in a wired virtual network environment and practical wireless environments supporting different types of traffic. The results show that SoftToken indeed provides better QoS performance in scenarios that require service differentiation (e.g. mixed voice over Internet protocol and best effort traffic scenarios). Copyright © 2013 John Wiley & Sons, Ltd.