bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sharing a predator: can an invasive alien pest affect the predation on a local pest?
Authors: Bompard Anaïs , Jaworski Coline C. , Bearez Philippe , Desneux Nicolas 
Published: April 2013

AbstractInvasive species can strongly affect biotic interactions in ecosystems, interacting both directly and indirectly with local species. In European tomato greenhouses, the invasive alien pest Tuta absoluta may impact the population dynamics of other pests like whiteflies. Besides inducing damages to the host plant and competing for resources with local pests, this alien species may exert a predator‐mediated interaction on local pests sharing common natural enemies. Biocontrol agents usually used against whiteflies may also prey upon T. absoluta and this could alter the dynamics of local pest populations. We evaluated possible resource competition and predator‐mediated interactions in a system involving one mirid predator Macrolophus pygmaeus and two pests, T. absoluta and a local whitefly, Bemisia tabaci, on greenhouse tomatoes. Results showed that both resource competition and predator‐mediated interactions occurred simultaneously. In the presence of the shared predator, there was a short‐term positive effect of T. absoluta on B. tabaci [up to 5.9‐fold increase of B. tabaci juveniles (egg + larvae) after four weeks]. However, in the long‐term there was a negative predator‐mediated interaction of T. absoluta on B. tabaci, i.e., after ten weeks the density of B. tabaci was 7.3‐fold lower in the presence of the invasive pest. We emphasize the critical role of generalist predators in managing both local and invasive alien pest populations and that the strength and direction of predator‐mediated indirect interactions can depend on the time scale considered.
Effect of diet delivered various concentrations of double-stranded RNA in silencing a midgut and a non-midgut gene of Helicoverpa armigera
Authors: Asokan R. , Chandra G. Sharath , Manamohan M. , Kumar N.K. Krishna 
Published: April 2013

AbstractRibonucleic acid interference (RNAi) is a sequence-specific gene silencing mechanism induced by double-stranded RNA (dsRNA). Recently, RNAi has gained popularity as a reverse genetics tool owing to its tremendous potential in insect pest management, which includes Helicoverpa armigera. However, its efficiency is mainly governed by dsRNA concentration, frequency of application, target gene, etc. Therefore, to obtain a robust RNAi response in H. armigera, we evaluated various concentrations of dsRNA and its frequency of applications delivered through diet in silencing a midgut gene, chymotrypsin and a non-midgut gene, juvenile hormone acid methyl transferase (jhamt) of H. armigera. The extent of target gene silencing was determined by employing reverse transcription quantitative real-time polymerase chain reaction (RT-qPCR). Our study revealed four significant findings: (i) single application of dsRNA elicited a delayed and transient silencing, while multiple applications resulted in early and persistent silencing of the above genes; (ii) silencing of the non-midgut gene (jhamt) through diet delivered dsRNA revealed prevalence of systemic silencing probably due to communication of silencing signals in this pest; (iii) the extent of silencing of chymotrypsin was positively correlated with dsRNA concentration and was negatively correlated with jhamt; (iv) interestingly, over-expression (15–18 folds) of an upstream gene, farnesyl diphosphate synthase (fpps), in juvenile hormone (JH) biosynthetic pathway at higher concentrations of jhamt dsRNA was the plausible reason for lesser silencing of jhamt. This study provides an insight into RNAi response of target genes, which is essential for RNAi design and implementation as a pest management strategy.
Mapping cation entry in photoreceptors and inner retinal neurons during early degeneration in the P23H-3 rat retina
Authors: ZHU YUAN , MISTRA STUTI , NIVISON-SMITH LISA , ACOSTA MONICA L. , FLETCHER ERICA L. , KALLONIATIS MICHAEL 
Published: April 2013

AbstractThe proline-23-histidine line 3 (P23H-3) transgenic rat carries a human opsin gene mutation leading to progressive photoreceptor loss characteristic of human autosomal dominant retinitis pigmentosa. The aim of the present study was to evaluate neurochemical modifications in the P23H-3 retina as a function of development and degeneration. Specifically, we investigated the ion channel permeability of photoreceptors by tracking an organic cation, agmatine (1-amino-4-guanidobutane, AGB), which permeates through nonspecific cation channels. We also investigated the activity of ionotropic glutamate receptors in distinct populations of bipolar, amacrine, and ganglion cells using AGB tracking in combination with macromolecular markers. We found elevated cation channel permeation in photoreceptors as early as postnatal day 12 (P12) suggesting that AGB labeling is an early indicator of impending photoreceptor degeneration. However, bipolar, amacrine, or ganglion cells displayed normal responses secondary to ionotropic glutamate receptor activation even at P138 when about one half of the photoreceptor layer was lost and apoptosis and gliosis were observed. These results suggest that possible therapeutic windows as downstream neurons in inner retina appear to retain normal function with regard to AGB permeation when photoreceptors are significantly reduced but not lost.
Paramedic Skills And Medications: Practice Options Utilized By Local Advanced Life Support Medical Directors
Authors: Garrison Herbert G. , Benson Nicholas H. , Whitley Theodore W. , Bailey Bob W. 
Published: April 2013

AbstractLocal advanced life support (ALS) medical directors in North Carolina choose the skills and medications they want utilized in their jurisdiction from a list of options authorized by the State Board of Medical Examiners. We surveyed all 35 medical directors of paramedic providers in the state to determine which optional skills and medications local medical directors allow to be used and, therefore, how they tailor their prehospital practices. Information concerning the urban or rural status of the paramedic service area, annual call volume, and the specialty classification of the medical director also were obtained.All of the medical directors surveyed responded. Twenty-one (60%) of the paramedic service areas were rural and 14 (40%) urban. Twenty-three physicians (66%) listed emergency medicine as their primary specialty. Annual call volumes ranged from 580 to 33,500. Skills allowed by >80% of the medical directors include: drawing blood, insertion of esophageal and endotracheal airways, defibrillation, cardioversion, and initiation of intravenous fluids prior to hospital contact. The majority permit the administration of bretylium, dopamine, NaCl injection, sodium bicarbonate, furosemide, sublingual nitroglycerin, diazepam, diphenhydramine, and morphine. The majority do not allow the use of positive-pressure ventilators and do not allow administration of dobutamine, nifedipine, procainamide, propranolol, local procaine, isoetharine, metaproterenol, nitroglycerin paste, 10% dextrose solution, methylprednisolone, mannitol, phenytoin, meperidine, or nitrous oxide. Nitroglycerin paste and dexamethasone were significantly (p<.05) more likely to be allowed in rural than in urban areas. No differences in utilization by medical director specialty classification or call volume were detected. The results suggest that, when given a choice, local ALS medical directors select a limited prehospital practice. Further study is warranted to determine why available skill and medication options are not utilized.
The efficacy of initial hydrocortisone administration at preventing posttraumatic distress in adult trauma patients: a randomized trial
Authors: Delahanty Douglas L. , Gabert-Quillen Crystal , Ostrowski Sarah A. , Nugent Nicole R. , Fischer Beth , Morris Adam , Pitman Roger K. , Bon John , Fallon William 
Published: April 2013

Objective/IntroductionSecondary pharmacological interventions have shown promise at reducing the development of posttraumatic stress disorder symptoms (PTSS) in preclinical studies. The present study examined the preliminary efficacy of a 10-day low-dose (20 mg bid) course of hydrocortisone at preventing PTSS in traumatic injury victims.MethodsSixty-four traumatic injury patients (34% female) were randomly assigned in a double-blind protocol to receive either a 10-day course of hydrocortisone or placebo initiated within 12 hours of the trauma. One-month and 3-months posttrauma participants completed an interview to assess PTSS and self-report measures of depression and health-related quality of life.ResultsHydrocortisone recipients reported fewer PTSD and depression symptoms, and had greater improvements in health-related quality of life during the first 3 months posttrauma than did placebo recipients. Hydrocortisone recipients who had never received prior mental health treatment had the lowest PTSD scores.ConclusionLow-dose hydrocortisone may be a promising approach to the prevention of PTSD in acutely injured trauma patients, and may be particularly efficacious in acutely injured trauma victims without a history of significant psychopathology.
Zum Erleben von altersbezogenen Veränderungen im Erwachsenenalter
Authors: Wahl Hans-Werner , Konieczny Christoph , Diehl Manfred 
Published: April 2013

Der vorliegenden Studie liegt das Konzept „Awareness of Age-Related Change” (AARC; Diehl & Wahl, 2010 ) und ein entsprechender Fragebogen zu Grunde. Die empirische Grundlage der Studie bildete eine Stichprobe von 265 Personen (69 % Frauen; 40 – 87 Jahre). Zunächst wurden in einer Kombination von explorativen und konfirmatorischen Analysen aus ursprünglich 60 generierten Items, die gleichermaßen Gewinne und Verluste in unterschiedlichen Bereichen altersbezogener Veränderungen beinhalteten, ein optimiertes Itemset von 2 x 16 Items identifiziert (Gewinnbasiertes AARC: Cronbachs alpha = .82; Verlustbasiertes AARC: Cronbachs alpha = .87; Interkorrelation: r = -.05; RMSEA = .045). Insgesamt zeigten sich auf dieser Messgrundlage im Wesentlichen die erwarteten Zusammenhänge. So korrelierte vor allem verlustbasiertes AARC deutlich positiv mit Neurotizismus, negativ mit Extraversion und negativ mit Indikatoren erfolgreichen Alterns. Insgesamt bestätigen die Befunde, dass Älterwerden vor allem durch ein negativ getöntes Alternsveränderungserleben charakterisiert ist.
Chaotic Boltzmann machines
Authors: Suzuki Hideyuki , Imura Jun-ichi , Horio Yoshihiko , Aihara Kazuyuki 
Published: April 2013

AbstractThe chaotic Boltzmann machine proposed in this paper is a chaotic pseudo-billiard system that works as a Boltzmann machine. Chaotic Boltzmann machines are shown numerically to have computing abilities comparable to conventional (stochastic) Boltzmann machines. Since no randomness is required, efficient hardware implementation is expected. Moreover, the ferromagnetic phase transition of the Ising model is shown to be characterised by the largest Lyapunov exponent of the proposed system. In general, a method to relate probabilistic models to nonlinear dynamics by derandomising Gibbs sampling is presented.
An analysis of splicing, actin-binding properties, heterodimerization and molecular interactions of the non-muscle α-actinins
Authors: Foley Kate S. , Young Paul W. 
Published: April 2013

The non-muscle α-actinin isoforms (actinin-1 and -4) are closely related dimeric actin filament cross-linking proteins. Despite high sequence similarity, unique properties have been ascribed to actinin-4 in particular. For example, actinin-4, but not actinin-1, is essential for normal glomerular function in the kidney, is overexpressed in several cancers and can translocate to the nucleus to regulate transcription. To understand the molecular basis for such isoform-specific functions we have, for the first time, comprehensively compared these proteins in terms of alternative splicing, actin-binding properties, heterodimer formation and molecular interactions. We find that the Ca2+-insensitive variant of actinin-4 is expressed only in the nervous system and thus cannot be regarded as a smooth muscle isoform, as is the case for the Ca2+-insensitive variant of actinin-1. The actin-binding properties of actinin-1 and -4 are similar and are unlikely to explain isoform-specific functions. Surprisingly, we reveal that actinin-1/-4 heterodimers, rather than homodimers, are the most abundant form of actinin in many cell lines. Finally, we use a proteomics approach to identify potential isoform-specific interactions. The results of the present study indicate that actinin-1 and -4 can readily form heterodimers composed of monomers that may have different properties and interacting proteins. This significantly alters our view of non-muscle actinin function.
Preoperative oral nutritional interventions in surgery, including arginine- and glutamine-enhanced supplements.
Authors: Brinkmann S. J. H. , Buijs N. , Luttikhold J. , Delavary B. M. , Niessen F. B. , Leeuwen P. A. M. van 
Published: April 2013

Abstract
The patients' condition prior to surgery is of major importance for clinical outcome. It is believed nowadays that artificial nutrition in the form of a preoperative drink may improve postoperative outcome. Until now, a clear overview concerning the effects of preoperative supplementation on patients' well-being has been lacking. The aim of this review is to summarize the results of randomized clinical trials investigating the effects of different preoperative supplements such as carbohydrate (CHO)-rich beverages, oral nutritional supplements (ONSs), immunonutrition and lemonades on clinical, metabolic and immunological parameters. We reviewed the relevant articles published between 1995 and 2012. Preoperative CHO-rich drinks appear to be safe, do not affect gastric emptying time and switch the fasted state to a fed state. Moreover, a significant reduction of postoperative insulin resistance, an improved well-being of the patient and prevention of surgery-induced immunodepression was found. For ONSs, beneficial effects were found according to muscle metabolism and strength, glucose storage and cost-effectiveness. Preoperative supplementation of immunonutrition resulted in improved immune function, restricted inflammatory response after surgery, prevention of organ damage, improved nutritional status with subsequently decreased postoperative complication rates and reduced length of hospital stay. Preoperative oral supplements have beneficial effects on many aspects of patient's well-being and recovery. Different supplements, preferably in combination with each other, can help to reduce postoperative complications after surgery and length of hospital stay. Nutritional support must not be overlooked when considering optimal surgical care.
First Report of Crown Gall, Caused by Agrobacterium tumefaciens on Soapberry (Sapindus delavayi) in China
Authors: Wang Y. J. , He Y. Y. , Xie Z. , Zhang L. Q. 
Published: April 2013

Soapberry (Sapindus delavayi (Franch.) Radlk.,) plants are widely grown as shade trees in the subtropical to tropical regions of China. In July 2011, large, aerial galls were observed on the above-ground trunks of 5-year-old soapberry plants in two commercial nursery gardens located in Zhejiang Province. Disease incidence was estimated to be 75%. The galls varied in weight from 2 to 24 g and in texture from soft and spongy to hard, and in some cases, the galls completely girdled the trunk. The trees with galls exhibited poor growth compared with healthy trees. Isolations from the grinded and macerated galls yielded nearly pure white, circular, and glistening bacterial colonies on Roy Sauer medium (2). Six random colonies from different galls were selected for bacterial identification, and showed the same morphological, physiological, and biochemical characters and 16S rDNA sequences. All six isolates (isolate SD01 to SD06) were gram negative, rod-shaped bacteria. Carbon source utilization testing with the Biolog GN Bacterial Identification System (version 3.50) confirmed the bacteria as Agrobacterium tumefaciens with a similarity of 0.90. The most-parsimonious tree from the maximum parsimony analysis (PHYLIP package, version 3.68, 500 replicates) of bacterial 16S rDNA gene sequences showed that A. tumefaciens SD01 (GenBank Accession No. JX997939) clustered phylogenetically most closely (99.5% similarity) with A. tumefaciens C58 (AE007870.2). Pathogenicity was confirmed by injecting 3- to 5-week old tomato and sunflower plants and 2-year-old soapberry with approximately 5 μl of the bacterial suspension (108 CFU/ml) in sterile, distilled water. Sterile distilled water was used as a negative control. Ten plants of each treatment were inoculated. Inoculated plants were then transferred to a greenhouse at 25°C. Typical tumors developed at the inoculation sites on tomatoes and sunflower plants 3 weeks after inoculation and on soapberry 6 weeks after inoculation. No symptoms were observed on the control plants. The bacteria that were readily reisolated from the inoculated plants exhibited the same morphological, physiological characters and 16S rDNA sequence as the original culture and were confirmed as A. tumefaciens, fulfilling Koch's postulates. A. tumefaciens is endemic to China and has a very wide host range (1). However, crown gall of soapberry has never been found in China and other countries. To our knowledge, this is the first report of A. tumefaciens on soapberry plants in China. References: (1) M. A. Escobar and A. M. Dandekar. Trends Plant Sci. 8:380, 2003. (2) L. W. Moore et al. Page 17 in: Laboratory Guide for Identification of Plant Pathogenic Bacteria. 3rd ed. N. W. Schaad et al., eds. The American Phytopathological Society, St. Paul, MN, 2001.
Esophageal Length
Authors: Moreau Brigitte , Kambites Sandra , Lévesque Dominique 
Published: April 2013

ABSTRACTBackground and Objectives:Many mathematical equations based on height have been developed to estimate the esophageal length (EL) in children. The aim of this study was to confirm whether the preexisting and most frequently used equation by Strobel et al is accurate in calculating the EL in our pediatric population. Our secondary goal was to evaluate whether a new formula could be developed using our nonsurgical and surgical populations' data for the correlation between patients' height and measured EL by esophageal manometry (EM).Methods:From 2000 to 2009, 116 children between the ages of 3 and 18 years without previous esophageal surgery underwent EM (n = 31) at the Montreal Children's Hospital. During the same period, 55 EMs were performed on 34 children with a previous history of esophageal surgery. For both groups, we collected the following data: height, EL calculated by the Strobel formula, and EL measured by EM.Results:The Strobel equation was inaccurate in predicting the EL. The calculated EL was 3.0 ± 0.32 cm longer than the EM measurements (P < 0.001). The height (H) of nonsurgical children was found to be highly predictive of the lower esophageal sphincter location (L), and the derived linear regression equation is L = 0.216 (H) + 7.13 [r2 = 0.85].Conclusions:This study confirmed that the Strobel formula is not sufficiently accurate to predict EL in the pediatric population that is between 3 and 18 years old. A correlation exists between height and esophageal sphincter location position. If EM is unavailable, the use of a new mathematical equation like ours can be considered.
Including people who experience homelessness: a scoping review of the literature
Authors: Norman Trudy , Pauly Bernadette 
Published: April 2013

PurposeWithout the voices of those impacted by homelessness, there is a risk that important understandings essential to the development of effective solutions to homelessness will remain obscured. The purpose of this paper is to provide an overview of the evidence base and insights into recommendations for development and implementation of policies and practices to promote meaningful involvement of people experiencing homelessness as part of a community response to homelessness in a mid‐size Canadian city.Design/methodology/approachA scoping literature review was conducted, focusing on homelessness and social exclusion/inclusion.FindingsBased on this review, the authors provide insights into the processes of social exclusion and inclusion as a beginning place for developing strategies for meaningful engagement in community responses to homelessness. Roots of social exclusion, towards social inclusion and creating social inclusion were three themes which emerged as central to developing inclusionary policy. First, the roots of social exclusion associated with homelessness are located in unequal power relations, highlighting contextual factors that produce exclusion with implications for health and well‐being. Second, towards social inclusion, reflects theoretical perspectives and principles that have been used to inform inclusionary practices. Third, creating inclusion highlights some strategies that can support inclusion for people experiencing homelessness and foster development of inclusionary policy.Originality/valueThere is little evidence of effective practices that promote social inclusion or attention to specific strategies that engage diverse homeless populations that account for gender, ethnicity and other important differences. A key next step is the development of guidelines for social inclusion at the organizational and municipal levels of decision making with those impacted by homelessness.
Family and friendship support networks among retirees
Authors: Requena Felix 
Published: April 2013

PurposeThe purpose of this paper is to provide an empirical analysis of factors that affect support networks among retirees in 13 countries.Design/methodology/approachIt examines two propositions drawing from support network theory and the classification of countries by welfare systems. It uses fixed‐effect causal models to examine how retirement and socio‐demographic variables influence kinship and friendship support networks. Data are drawn from the Social Relations and Support Systems module of the International Social Survey Programme 2001.FindingsThe results show that retirees' friendship‐based support networks are almost one‐third smaller than those of working persons. Furthermore, this difference is greater in welfare systems that spend more on social well‐being.Research limitations/implicationsHowever, the relationship between informal support networks and welfare systems is complex, which indicates a need to further the debate on the co‐existence of formal and informal aid systems.Originality/valueThis study's main sociological confirmation is that the relationship between the size of support networks and the type of welfare system is irregular and complex. The results make a significant contribution to the debate on the relationship between formal and informal care among a group of people during a critical life‐cycle phase, such as retirement.