bluuebunny/crossref_metadata_2025_split huggingface dataset:
Undetected permanent dental inflammation as a possible trigger for brain abscesses? A retrospective analysis over the last 2 decades
Authors: Olivier Maximilian , Kraus Luisa Mona , Brandenburg Leonard Simon , Andereggen Lukas , Fung Christian , Beck Jürgen , Schnell Oliver , Cipriani Debora 
Published: July 2024

Abstract

Background
Recently, there is increasing evidence that the proportion of odontogenic brain abscesses is greater than previously known. In this study, we aim to differentiate the oral infections as triggers more precisely and to classify them in the clinical setting.

Methods
For analysis, we conducted a retrospective single center study. We reviewed patients with brain abscesses who have undergone treatment in the University Hospital of Freiburg, Germany in the period between 2000–2021. Inclusion required two main criteria: 1. The brain abscess must not have an other focus than odontogenic. 2. The microbial spectrum identified in the brain abscess must be consistent with an odontogenic origin.

Results
Of 217 brain abscess patients, 26 met the inclusion criteria. 42% (11 patients) suffered from immunosuppressive conditions. Odontogenic foci were diagnosed in 18 cases (69%). Neurologic deficits included vigilance reduction and hemiparesis. Pathogens of the Streptococcus anginosus group were the most frequent causative agent (21 cases, 81%). Metronidazole (54%) and ceftriaxone (42%) were part of the targeted antibiotic therapy. All brain abscesses were surgically treated. Teeth were extracted in 14 of 17 cases for focus control. 18 cases (72%) showed complete or partial resolution of neurologic symptoms and 3 cases were fatal.

Conclusion
Apparently silent or chronic oral infections are sufficient to cause bacterial colonization of the brain, especially in immunocompromised patients. Therefore, special care should be taken to maintain good oral health. An interdisciplinary management should become a standard to prevent and treat the occurrence of brain abscesses.
A potential acaricide of Moutan Cortex essential oil encapsulated in nanoemulsion and mesoporous silica nanoparticles against the house dust mite Dermatophagoides farinae
Authors: Teng Qiao , Li Yuanyuan , Cai Yuanyuan , Guo Junjie , Zou Minghui , Xue Qiqi , Tang Xiaoniu , Li Xiangzi , Zhao Jinhong 
Published: July 2024

AbstractMoutan Cortex essential oil (MCEO) is considered to be a promising botanical insecticide. However, like most oils, MECO has several limitations, including instability and poor solubility. Nanoencapsulation technology is an excellent strategy for stabilizing essential oils because of its controlled release, enhanced efficacy, and strengthened biological activity. The present study investigated the acaricidal efficacy of pure MCEO and its encapsulated nanoemulsion (NE) and mesoporous silica nanoparticles (MSNs) against the house dust mite Dermatophagoides farinae using contact bioassays, fumigant bioassays, repellent bioassays, and the observation of toxic symptoms. MCEO-MSNs obtained in the study successfully encapsulated MCEO with an encapsulation efficiency of 63.83%. The acaricidal mortality experiments revealed that MCEO-NE and MCEO-MSN showed more significant toxicity against D. farinae than did pure MCEO. The nanomaterials showed better larvicidal and nymphicidal activities than pure MCEO at a high concentration (12-h LC90). Notably, the repellent effect experiment showed that MCEO-NE and MCEO-MSN had long-term and stable repellent effects on D. farinae, indicating the sustained release and persistence of the nanomaterials. More toxicity symptoms were observed in the IM-type group than in the KD-type group, suggesting that the MCEO nanoparticles have adverse effects on the respiratory system. Nanomaterials and MCEO promoted superoxide dismutase (SOD) activity and inhibited acetylcholinesterase (AChE) activity in D. farinae. In addition, the binding sites of paeonol to SOD and AChE were found through molecular docking. These findings demonstrate the potential of MCEO as a biological acaricide, which merits further investigation.
Tissue Engineered 3D Constructs for Volumetric Muscle Loss
Authors: Gahlawat Sonal , Oruc Doga , Paul Nikhil , Ragheb Mark , Patel Swati , Fasasi Oyinkansola , Sharma Peeyush , Shreiber David I. , Freeman Joseph W. 
Published: July 2024

AbstractSevere injuries to skeletal muscles, including cases of volumetric muscle loss (VML), are linked to substantial tissue damage, resulting in functional impairment and lasting disability. While skeletal muscle can regenerate following minor damage, extensive tissue loss in VML disrupts the natural regenerative capacity of the affected muscle tissue. Existing clinical approaches for VML, such as soft-tissue reconstruction and advanced bracing methods, need to be revised to restore tissue function and are associated with limitations in tissue availability and donor-site complications. Advancements in tissue engineering (TE), particularly in scaffold design and the delivery of cells and growth factors, show promising potential for regenerating damaged skeletal muscle tissue and restoring function. This article provides a brief overview of the pathophysiology of VML and critiques the shortcomings of current treatments. The subsequent section focuses on the criteria for designing TE scaffolds, offering insights into various natural and synthetic biomaterials and cell types for effectively regenerating skeletal muscle. We also review multiple TE strategies involving both acellular and cellular scaffolds to encourage the development and maturation of muscle tissue and facilitate integration, vascularization, and innervation. Finally, the article explores technical challenges hindering successful translation into clinical applications.
Projection generalized correntropy twin support vector regression
Authors: Wang Zhongyi , Yang Yonghui , Wang Luyao 
Published: July 2024

AbstractA projection generalized maximum correntropy twin support vector regression algorithm is proposed. The generalized correntropy function is added into the loss function of adaptive filtering, maximizing which can suppress the interference of noise or outliers.Considering the fact that single-shift projection twin support vector regression cannot observe local information of samples, a complete ensemble empirical mode decomposition with adaptive noise (CEEMDAN) combined with wavelet soft threshold denoising is used to assign weights to samples. The CEEMDAN is used to decompose the original data, calculate the Pearson correlation coefficient between the mode functions and the original data. The mode with low correlation is filtered by wavelet based algorithm with soft-threshold to get the reconstructed samples after noise reduction. Smaller weights will be assigned to reconstructed samples with significant differences from the original data, while larger weights will be assigned to reconstructed samples with smaller differences. Similarly, the empirical risk term in the cost function is also assigned calculated weights to improve the robustness. Due to the use of empirical mode decomposition, the proposed method is particularly suitable for processing non-stationary data. Experimental results on artificial and UCI datasets verified the effectiveness of the algorithm.
Exploring students’ perspectives on Generative AI-assisted academic writing
Authors: Kim Jinhee , Yu Seongryeong , Detrick Rita , Li Na 
Published: July 2024

Abstract
The rapid development of generative artificial intelligence (GenAI), including large language models (LLM), has merged to support students in their academic writing process. Keeping pace with the technical and educational landscape requires careful consideration of the opportunities and challenges that GenAI-assisted systems create within education. This serves as a useful and necessary starting point for fully leveraging its potential for learning and teaching. Hence, it is crucial to gather insights from diverse perspectives and use cases from actual users, particularly the unique voices and needs of student-users. Therefore, this study explored and examined students' perceptions and experiences about GenAI-assisted academic writing by conducting in-depth interviews with 20 Chinese students in higher education after completing academic writing tasks using a ChatGPT4-embedded writing system developed by the research team. The study found that students expected AI to serve multiple roles, including multi-tasking writing assistant, virtual tutor, and digital peer to support multifaceted writing processes and performance. Students perceived that GenAI-assisted writing could benefit them in three areas including the writing process, performance, and their affective domain. Meanwhile, they also identified AI-related, student-related, and task-related challenges that were experienced during the GenAI-assisted writing activity. These findings contribute to a more nuanced understanding of GenAI's impact on academic writing that is inclusive of student perspectives, offering implications for educational AI design and instructional design.
Early Modern Deviant Burial in Prehistoric Monuments in Sweden
Authors: Rundkvist Martin 
Published: July 2024

AbstractThis study deals with Early Modern burials in ancient monuments located nowhere near churches or execution sites. Examples are given from four prehistoric sites in different Swedish provinces, dating from the Early Neolithic through the Roman Period, with a total of 15 buried Early Modern individuals. Written sources along with details of the burial rite suggest that they are plague burials. Such were not welcome in churchyards because of concerns over the poorly understood contagion. Why people all over Sweden occasionally targeted ancient monuments specifically for this purpose is not clear. In one case, they saw the monument as the remains of a church. More generally, they knew that much older burials sanctified and lent some prior sanction to those sites.
Should a Yogi Be Healthy? Health Concepts in Early Haṭhayoga Texts
Authors: Shalev Hagar 
Published: July 2024

AbstractHaṭhayoga texts, influential in the development of modern posture-based yoga, offer a conceptual framework intertwining physical cultivation, health, and soteriological aims. This article explores two interconnected inquiries regarding early Haṭhayoga texts: How do they conceptualize health, and how do they perceive the relationship between health and soteriology? These investigations illuminate the place of health in early yoga texts within Hindu traditions prior to its global recognition.This article reveals that early haṭha texts present a holistic approach to health, highlighting the interconnectedness of curing the mind and healing the body. This process entails not only eradicating physical diseases but also the transcendence of all forms of suffering. The transformative process of eliminating the misleading self-identity (ahaṁkāra) is pivotal, leading directly to health. This relationship extends beyond metaphorical comparisons of healing ignorance and suffering. This ontological framework proposes a harmonious integration between the material and soteriological realms, viewing the healthy body as a physical manifestation of the divine essence. Thus, the emergence of the biomedical discourse surrounding yoga in modern times did not occur autonomously. Haṭhayoga, with its roots dating back to the beginning of the second millennium CE, played a crucial role in shaping this historical transformation.
Quantifying growth, erosion and dislodgement rates of farmed kelp (Saccharina latissima) to examine the carbon sequestration potential of temperate seaweed farming
Authors: Canvin Maxine C. , Moore Pippa J. , Smale Dan A. 
Published: July 2024

AbstractSeaweed cultivation, including kelp species, is rapidly expanding in many regions. A widely assumed co-benefit of seaweed farming is increased local carbon sequestration rates (thereby contributing to climate change mitigation), although direct field-based measurements of carbon assimilation and release are largely lacking. We quantified growth, erosion and dislodgement rates of farmed Saccharina latissima in Porthallow Bay (Cornwall, UK) throughout a typical cultivation season to provide insights into the carbon sequestration potential of small-scale kelp farms. Blade elongation rates increased from ~ 1.3 cm day−1 to ~ 2.3 cm day−1 in March–April, before declining to 1.4 cm day−1 by May. Meanwhile, erosion rates remained low, ranging from ~ 0.5 to ~ 0.8 cm day−1. Dislodgement rates decreased from 20% of plants in January–February to 5% in April–May. Rates of carbon accumulation and loss increased from January to May, related to an increase in standing stock. Conservative first-order estimates suggest that the farm captures 0.14 t C ha−1 y−1, of which up to 70% is released into the environment as particulate organic carbon. Based on previous estimates of carbon burial and storage rates, the farm may sequester 0.05 t CO2e ha−1 y−1. These values suggest that scaling-up European kelp farming should be motivated by other co-benefits, such as low-carbon product alternatives, job creation and potential biodiversity gains, and not be solely driven by a perceived meaningful increase in carbon sequestration. Importantly, further information needs to be obtained from a variety of cultivation sites to develop a better understanding of carbon dynamics associated with kelp farms.
Analysis of CeO2/SiO2 double-layer thin film stack with antireflection effect for silicon solar cells
Authors: Kanmaz Imran , Tomakin Murat , Uzum Abdullah 
Published: July 2024

AbstractThis study introduces CeO2/SiO2 double-layer film stacks and its antireflection coating effect. Optical properties were analyzed by spectrophotometer measurements; surface morphology and cross-sections were observed by Scanning Electron Microscopy (SEM); elemental distributions and crystallographic properties were determined by Energy Dispersive Spectroscopy (EDS) and X-ray Diffraction (XRD) measurements. Average reflectance of single-layer 0.3MSiO2, 0.6MSiO2, and 0.3MCeO2 thin films were 30.54%, 20.12%, and 14.23%, respectively. Average reflectance was decreased significantly down to 5.9% by 0.3MCeO2/0.6MSiO2 double-layer thin films comparing to those of the results of single-layer films and bare silicon surface reflection (~40%). Antireflective effect of the films on solar cells was estimated by simulation using the measured reflection data. Simulated solar cells indicate that 0.3MCeO2/0.6MSiO2 double-layer antireflective coatings are capable to increase the efficiency significantly and conversion efficiency of 21.7% could be achieved.
Unmasking Street Harassment in Spain: Prevalence, Psychological Impact, and the Role of Sexism in Women’s Experiences
Authors: Contreras-Merino Ana M. , Farhane-Medina Naima Z. , Castillo-Mayén Rosario 
Published: July 2024

AbstractStreet harassment is a widespread problem that affects women from all backgrounds, often leading to negative psychological consequences such as anxiety, depression, and reduced self-worth. Despite the pioneering development of laws protecting women’s rights, Spanish culture often normalizes this type of violence against women, and research on this context remains limited. To address this gap, we conducted a cross-sectional study with 245 women in Spain to investigate the occurrence and impact of street harassment on psychological well-being. We used the Street Harassment Assessment Scale, a self-report measure designed to evaluate the prevalence and frequency of street harassment, and explored its association with anxiety, fear of rape, avoidance behavior, self-esteem, and adherence to sexist beliefs. The results showed that 98% of women experienced street harassment, with 80% reporting monthly occurrences. The frequency of street harassment was correlated with increased anxiety, fear of rape and avoidance behavior, and lower self-esteem. Additionally, the results supported the link between the endorsement of sexist ideology and lower identification of events. Collectively, the results underscore the negative impact of street harassment on women’s well-being and freedom, highlighting its role as a patriarchal tool that perpetuates female objectification and subordination. An integrative feminist perspective involving various fields, including psychology, public policy, and education, among others, is necessary to create safer environments for women.
Comparison of in-vitro orchid media solutions for Prosthechea cochleata (L.) W.E. Higgins vars. diandra and triandra
Authors: Bartel Lauren G. , Downing Jason 
Published: July 2024

AbstractProsthechea cochleata or clamshell orchid is recognized as a species of both conservation and commercial importance. It has long been prized by orchid breeders and growers for its unique flower and hardy disposition. The commercial market has failed to meet the demand for this species since it is still targeted for illegal collection in the wild. This study examines the effectiveness of the banana powder on two variants (var. diandra and var. triandra) with disparate home ranges and levels of genetic diversity using two commercially available agar-based media (PhytoTechnology P668 and P748). Undifferentiated protocorms of the two variants were monitored for shoot growth and differentiation across a period of 156 days. The growth media with 3% banana powder supplement (P748) was more effective in initiating shoot formation in both P. cochleata variants compared to control media (P668) (F = 27.15, p < 0.001, df = 81). The diandrous variant grown with banana showed the highest mean shoot count (28.67 shoots/flask) at the end of the monitoring period. Results suggest that banana supplement is an effective source of plant growth regulators and organic nutrients necessary to promote shoot formation and seedling development in this species. This research is important for the conservation of P. cochleata as it identifies an effective and cost-efficient method for in vitro propagation, which can aid in increasing the ex-situ and in situ populations of this threatened species. Additionally, the findings have implications for commercial orchid production, as it can potentially improve the cultivation and yield of this species for economic purposes.
Histological and chemical view on parotid duct sialolithiasis in the Slovakian warmblood mare
Authors: Korim Filip , Revajová Viera , Koľvek Filip , Bujňák Lukáš , Hreus Sebastián , Všianský Dalibor 
Published: July 2024

AbstractThe parotid duct has been reported to be the most common site of sialoliths in horses. In this case report, we described the first confirmed case of the equine sialolithiasis in Slovakia. The work was aimed to describe the transcutaneous approach to removing the sialolith, which manifested as a hard painless mass in the area of the maxillary cheek teeth, in a 14-year-old Slovakian warmblood mare. Pathological-anatomical and histological examination after extirpation confirmed the presence of parotid duct ectasia resulting from calculus. The mineral composition of the sialolith was determined with atomic absorption spectroscopy using X-ray powder diffraction. The sialolith was successfully extirpated transcutaneously, without complications or recurrence.
No association between markers of systemic inflammation and endothelial dysfunction with Alzheimer’s disease progression: a longitudinal study
Authors: van Setten Arne , Uleman Jeroen F. , Melis René J. F. , Lawlor Brian , Riksen Niels P. , Claassen Jurgen A. H. R. , de Heus Rianne A. A. ,   on behalf of NILVAD Study Group, Segurado Ricardo , Kennelly Sean , Rikkert Marcel G. M. Olde , Howard Robert , Pasquier Florence , Börjesson-Hanson Anne , Tsolaki Magda , Lucca Ugo , Molloy D. William , Coen Robert , Riepe Matthias W. , Kálmán János , Kenny Rose Anne , Cregg Fiona , O’Dwyer Sarah , Walsh Cathal , Adams Jessica , Banzi Rita , Breuilh Laetitia , Daly Leslie , Hendrix Suzanne , Aisen Paul , Gaynor Siobhan , Sheikhi Ali , Taekema Diana G. , Verhey Frans R. , Nemni Raffaello , Nobili Flavio , Franceschi Massimo , Frisoni Giovanni , Zanetti Orazio , Konsta Anastasia , Anastasios Orologas , Nenopoulou Styliani , Tsolaki-Tagaraki Fani , Pakaski Magdolna , Dereeper Olivier , de la Sayette Vincent , Sénéchal Olivier , Lavenu Isabelle , Devendeville Agnès , Calais Gauthier , Crawford Fiona , Mullan Michael , Berglund Maria A. , Claassen Jurgen A. , de Heus Rianne A. , de Jong Daan L. K. , Godefroy Olivier , Hutchinson Siobhan , Ioannou Aikaterini , Jonsson Michael , Kent Annette , Kern Jürgen , Nemtsas Petros , Panidou Minoa-Kalliopi , Abdullah Laila , Paris Daniel , Santoso Angelina M. , van Spijker Gerrita J. , Spiliotou Martha , Thomoglou Georgia , Wallin Anders 
Published: July 2024

Abstract
Introduction
Systemic inflammation and endothelial dysfunction are potentially modifiable factors implicated in Alzheimer’s disease (AD), which offer potential therapeutic targets to slow disease progression.

Methods
We investigated the relationship between baseline circulating levels of inflammatory (TNF-α, IL-1ß) and endothelial cell markers (VCAM-1, ICAM-1, E-selectin) and 18-month cognitive decline (ADAS-cog12) in 266 mild-to-moderate AD patients from the NILVAD study. We employed individual growth models to examine associations, potential mediation, and interaction effects while adjusting for confounders.

Results
The average increase in ADAS-cog12 scores over all patients was 8.1 points in 18 months. No significant association was found between the markers and the rate of cognitive decline. Mediation analysis revealed no mediating role for endothelial cell markers, and interaction effects were not observed.

Discussion
Our results do not support the role of systemic inflammation or endothelial dysfunction in progression in persons with AD.
Assessing the Prevalence of Male Obesity-Associated Gonadal Dysfunction in Severe Obesity: A Focus on the Impact of Bariatric Surgery and Surgical Approaches
Authors: Bombardieri Alessio , Bufano Annalisa , Fralassi Noemi , Ciuoli Cristina , Benenati Nicoletta , Dalmiglio Cristina , Voglino Costantino , Tirone Andrea , Vuolo Giuseppe , Castagna Maria Grazia 
Published: July 2024

Abstract
Purpose
Obesity is an important risk factor for secondary hypogonadism in men. Several studies evaluated the impact of bariatric surgery on gonadal function in men, proving an improvement in testosterone levels, without yet a global consensus on the impact of different surgical approaches. Objectives of the study are: to estimate the prevalence of obesity-associated gonadal dysfunction among men with severe obesity; to evaluate the response to bariatric surgery in terms of resolution of this condition, distinguishing between restrictive and restrictive-malabsorptive surgery.

Methods
We conducted a retrospective evaluation of 413 males with severe obesity (BMI 44.7 ± 8.3 kg/m2). A subgroup of them (61.7%) underwent bariatric surgery. Anthropometric assessment (weight, BMI, waist and hip circumference), metabolic (glyco-lipidic asset and urate) and hormonal (morning gonadotropin and total testosterone) assessments were carried out at baseline and 3–6 months post-surgery.

Results
Using a TT threshold of 2.64 ng/ml, 256 out of 413 (62%) patients were categorized as having biochemical hypogonadism. At multivariate analysis, the only parameter significantly associated with biochemical hypogonadism, was BMI value (p = 0.001). At 3–6 months after surgery, during the acute weight loss phase, only 20.1% of patients still had biochemical hypogonadism. At multivariate analysis, which included age, presurgical BMI, pre-surgical TT, surgical approach and %EWL, presurgical TT levels (p = 0.0004), %EWL (p = 0.04), and mixed restrictive-malabsorptive surgery (p = 0.01), were independently associated with the recovery of gonadal function.

Conclusions
The results of this study underscore the potential reversibility of obesity-associated gonadal dysfunction through bariatric surgery, highlighting the importance of considering surgical approach.

Graphical Abstract