bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rapid Screening of Immobilized Amine CO2 Sorbents for Steam Stability by Their Direct Contact with Liquid H2O
Authors: Wilfong Walter Christopher , Kail Brian W. , Gray McMahan L. 
Published: May 2015

AbstractRapid testing of hydrophilic and hydrophobic basic immobilized amine sorbents (BIAS) for CO2 capture stability under practical conditions was achieved by direct contact of the sorbents with flowing liquid water. Losses in both CO2 capture capacity and amine content of sorbents after exposure to 0.5 mL min−1 of H2O at 25 °C for 40 min followed similar trends as losses observed after exposure to N2/steam (105 °C, 7 % H2O) for 10 h. We also found that hydrophobic TMPED helped stabilize sorbents to H2O, which was confirmed by DRIFTS and combined TGA‐DSC.
Nanobarcoded superparamagnetic iron oxide nanoparticles for nanomedicine: Quantitative studies of cell–nanoparticle interactions by scanning image cytometry
Authors: Eustaquio Trisha , Leary James F. 
Published: May 2015

AbstractOligonucleotide‐functionalized nanoparticles (NPs) are promising agents for nanomedicine, but the potential in vitro nanotoxicity that may arise from such conjugates has yet to be evaluated in a dose response manner. Since nanomedicine functions on the single‐cell level, measurements of nanotoxicity should also be performed as such. In vitro single‐cell nanotoxicity assays based on scanning image cytometry are used to study a specific type of oligo‐functionalized NP, “nanobarcoded” superparamagnetic iron oxide NPs (NB‐SPIONs). The selected panel of single‐cell assays measures well‐known modes of nanotoxicity—apoptosis, necrosis, generation of reactive oxygen species (ROS), and cell number. Using these assays, the cytotoxicity of two sizes of NB‐SPIONs (10 nm and 30 nm core size) was compared to the parent NP, carboxylated SPIONs (COOH‐SPIONs). The results suggest that the conjugated NB confers a biocompatible coating that protects against cytotoxicity at very high SPION doses, but both NB‐ and COOH‐SPIONs of either size generally have low in vitro cytotoxicity at physiologically relevant doses. © 2015 International Society for Advancement of Cytometry
Cognitive and emotional functioning in binge‐eating disorder: A systematic review
Authors: Kittel Rebekka , Brauhardt Anne , Hilbert Anja 
Published: May 2015

ABSTRACTObjectiveBinge‐eating disorder (BED) is characterized by recurrent episodes of binge eating and is associated with eating disorder and general psychopathology and overweight/obesity. Deficits in cognitive and emotional functioning for eating disorders or obesity have been reported. However, a systematic review on cognitive and emotional functioning for individuals with BED is lacking.MethodA systematic literature search was conducted across three databases (Medline, PubMed, and PsycINFO). Overall, n = 57 studies were included in the present review.ResultsRegarding cognitive functioning (CoF), individuals with BED consistently demonstrated higher information processing biases compared to obese and normal‐weight controls in the context of disorder‐related stimuli (i.e., food and body cues), whereas CoF in the context of neutral stimuli appeared to be less affected. Thus, results suggest disorder‐related rather than general difficulties in CoF in BED. With respect to emotional functioning (EmF), individuals with BED reported difficulties similar to individuals with other eating disorders, with a tendency to show less severe difficulties in some domains. In addition, individuals with BED reported greater emotional deficits when compared to obese and normal‐weight controls. Findings suggest general difficulties in EmF in BED. Thus far, however, investigations of EmF in disorder‐relevant situations are lacking.DiscussionOverall, the cross‐sectional findings indicate BED to be associated with difficulties in CoF and EmF. Future research should determine the nature of these difficulties, in regards to general and disorder‐related stimuli, and consider interactions of both domains to foster the development and improvement of appropriate interventions in BED.
Synthesis and physical properties of novel estolides from dicarboxylic acids and methyl ricinoleate
Authors: Sammaiah Arukali , Padmaja Korlipara V. , Prasad Rachapudi B.N. 
Published: May 2015

Castor oil is an attractive feedstock for the preparation of a variety of industrially important products due to the presence of ricinoleic acid with hydroxyl functionality up to 85–90%. Methyl ricinoleate was esterified with different dicarboxylic acids to prepare a series of a new class of estolides under solvent and catalyst‐free conditions. The products were evaluated for their physico‐chemical and lubricant properties. The estolide esters have a wide viscosity range varying from ISO VG 15 to 46. All the products exhibited excellent pour points (−48 to <−60°C) outperforming the reported estolide products. Among the estolide esters, 2‐ethyl‐1‐hexyl esters of monoacid estolides exhibited higher oxidative onset values (199°C). Dimer estolides and 2‐ethylhexyl esters of monoacid estolides exhibited better thermal stability compared to all other estolide esters. The products having low pour points can be potential base oils for low temperature lubricant applications.Practical applications: Synthesis of potential lubricant basestocks from indigenous non‐edible oil under solvent and catalyst‐free conditions. Prepared biolubricants with very low pour points, which is difficult to achieve with vegetable oil derivatives. The products are potential candidates for low temperature applications.Estolides with low pour points.
Mercury and selenium concentrations in skeletal muscle, liver, and regions of the heart and kidney in bearded seals from Alaska, USA
Authors: Correa Lucero , Castellini J. Margaret , Quakenbush Lori T. , O'Hara Todd M. 
Published: May 2015

Abstract

Mean concentrations of total mercury ([THg]) and selenium ([TSe]) (mass and molar-based) were determined for 5 regions of the heart and 2 regions of the kidney of bearded seals (Erignathus barbatus) harvested in Alaska, USA, in 2010 and 2011. Mean [THg] and [TSe] of bearded seal liver and skeletal muscle tissues were used for intertissular comparison. The Se:Hg molar ratios were used to investigate elemental associations and potential antioxidant protection against Hg toxicosis. Age was an important factor in [THg] and Se:Hg molar ratios in heart and kidney. Small but statistically significant differences in mean [THg] occurred among some of the 5 heart regions (p &lt; 0.05). Mean [THg] was highest in liver, 3.057 µg/g, and lowest in heart left ventricle, 0.017 µg/g. Mean [THg] ranked: liver &gt; kidney cortex &gt; kidney medulla &gt; skeletal muscle &gt; heart left ventricle (p &lt; 0.001). Mean [TSe] was highest in liver, 3.848 µg/g, and lowest in heart left ventricle, 0.632 µg/g. Mean [TSe] ranked: liver &gt; kidney cortex &gt; kidney medulla &gt; skeletal muscle &gt; heart left ventricle (p &lt; 0.001). The Se:Hg molar ratios were significantly greater than 1.0 in all tissues (p &lt; 0.001) and represented baselines for normal [TSe] under relatively low [THg]. Mean Se:Hg molar ratios ranked: heart left ventricle &gt; kidney medulla &gt; kidney cortex (p &lt; 0.001). Environ Toxicol Chem 2015;34:2403–2408. © 2015 SETAC
Aroma profile of the anise‐like odour mushroom Cortinarius odorifer
Authors: Kleofas Vanessa , Popa Flavius , Fraatz Marco A. , Rühl Martin , Kost Gerhard , Zorn Holger 
Published: May 2015

AbstractThe aroma compounds of fruiting bodies of C. odorifer were extracted by means of liquid/liquid extraction and purified by solvent assisted flavour evaporation (SAFE). The odour active compounds were identified by gas chromatography‐mass spectrometry and olfactometry on two columns of different polarity and described by sensory detection. The volatilom of C. odorifer is reported here for the first time. Additionally, an aroma extract dilution analysis (AEDA) was performed to identify the main flavour compounds. Finally, the volatiles were quantified by GC flame ionization detection (GC‐FID). The main odour compound of C. odorifer was methyl p‐anisate with an FD factor of 8,192 and a concentration of 120 mg kg‐1. Methyl p‐anisate was also the compound responsible for the characteristic anise‐like odour of C. odorifer. Copyright © 2015 John Wiley & Sons, Ltd.
Paecilomycines A and B, Novel Diterpenoids, Isolated from Insect‐Pathogenic Fungi Paecilomyces sp. ACCC 37762
Authors: Zhou Kun , Zhao Xiao‐Ling , Han Li‐Ping , Cao Meng‐Meng , Chen Chuan , Shi Bao‐Zhong , Luo Du‐Qiang 
Published: May 2015

AbstractTwo new diterpenoids, named paecilomycine A (1) and paecilomycine B (2), including a novel skeleton with a five‐membered lactone ring, together with three known labdane diterpenoids, rel‐(1R,3S,4aS,5R,8aS)‐5‐[(3E)‐4‐carboxy‐3‐methylbut‐3‐en‐1‐yl]decahydro‐3‐hydroxy‐1,4a‐dimethyl‐6‐methylidenenaphthalene‐1‐carboxylic acid (3), botryosphaerin E (4), and agathic acid (5), were isolated from solid culture of the insect pathogenic fungi strain Paecilomyces sp. The structures of all compounds were established on the basis of comprehensive spectroscopic studies. The relative configurations of 1 and 2 were determined by single‐crystal X‐ray diffraction analyses.
A large-scale field trial of thin-layer capping of PCDD/F-contaminated sediments: Sediment-to-water fluxes up to 5 years post-amendment
Authors: Cornelissen Gerard , Schaanning Morten , Gunnarsson Jonas S , Eek Espen 
Published: May 2015

Abstract
The longer-term effect (3–5 y) of thin-layer capping on in situ sediment-to-surface water fluxes was monitored in a large-scale field experiment in the polychlorinated dibenzodioxin and dibenzofuran (PCDD/F) contaminated Grenlandfjords, Norway (4 trial plots of 10 000 to 40 000 m2 at 30 to 100 m water depth). Active caps (designed thickness 2.5 cm) were established in 2 fjords, consisting of dredged clean clay amended with powdered activated carbon (PAC) from anthracite. These active caps were compared to 2 nonactive caps in one of the fjords (designed thickness 5 cm) consisting of either clay only (i.e., without PAC) or crushed limestone. Sediment-to-water PCDD/F fluxes were measured in situ using diffusion chambers. An earlier study showed that during the first 2 years after thin-layer capping, flux reductions relative to noncapped reference fields were more extensive at the fields capped with nonactive caps (70%–90%) than at the ones with PAC-containing caps (50%–60%). However, the present work shows that between 3 and 5 years after thin-layer capping, this trend was reversed and cap effectiveness in reducing fluxes was increasing to 80% to 90% for the PAC caps, whereas cap effectiveness of the nonactive caps decreased to 20% to 60%. The increasing effectiveness over time of PAC-containing “active“ caps is explained by a combination of slow sediment-to-PAC mass transfer of PCDD/Fs and bioturbation by benthic organisms. The decreasing effectiveness of “nonactive“ limestone and clay caps is explained by deposition of contaminated particles on top of the caps. The present field data indicate that the capping efficiency of thin active caps (i.e., enriched with PAC) can improve over time as a result of slow diffusive PCDD/F transfer from sediment to PAC particles and better mixing of the PAC by bioturbation. Integr Environ Assess Manag 2016;12:216–221. © 2015 SETAC
Key Points
The largest field trial on thin-layer capping with activated carbon (AC) to date was performed in a dioxin-contaminated fjord in Norway. Long-term (3 to 5 years) effectiveness for AC-containing caps increased over time, whereas the opposite effect was observed for nonactive limestone and clay caps. The increasing effectiveness of AC caps is explained by the slow sediment-to-AC mass transfer of dioxins. The decreasing effectiveness of nonactive caps is explained by deposition of contaminated particles on top of the caps.
Design of antimicrobial peptides conjugated biodegradable citric acid derived hydrogels for wound healing
Authors: Xie Zhiwei , Aphale Nikhil V. , Kadapure Tejaswi D. , Wadajkar Aniket S. , Orr Sara , Gyawali Dipendra , Qian Guoying , Nguyen Kytai T. , Yang Jian 
Published: May 2015

AbstractWound healing is usually facilitated by the use of a wound dressing that can be easily applied to cover the wound bed, maintain moisture, and avoid bacterial infection. In order to meet all of these requirements, we developed an in situ forming biodegradable hydrogel (iFBH) system composed of a newly developed combination of biodegradable poly(ethylene glycol) maleate citrate (PEGMC) and poly(ethylene glycol) diacrylate (PEGDA). The in situ forming hydrogel systems are able to conform to the wound shape in order to cover the wound completely and prevent bacterial invasion. A 2k factorial analysis was performed to examine the effects of polymer composition on specific properties, including the curing time, Young's modulus, swelling ratio, and degradation rate. An optimized iFBH formulation was achieved from the systematic factorial analysis. Further, in vitro biocompatibility studies using adult human dermal fibroblasts (HDFs) confirmed that the hydrogels and degradation products are not cytotoxic. The iFBH wound dressing was conjugated and functionalized with antimicrobial peptides as well. Evaluation against bacteria both in vitro and in vivo in rats demonstrated that the peptide‐incorporated iFBH wound dressing offered excellent bacteria inhibition and promoted wound healing. These studies indicated that our in situ forming antimicrobial biodegradable hydrogel system is a promising candidate for wound treatment. © 2015 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 103A: 3907–3918, 2015.
Preparation and characterization of (PCL‐crosslinked‐PEG)/hydroxyapatite as bone tissue engineering scaffolds
Authors: Koupaei Narjes , Karkhaneh Akbar , Daliri Joupari Morteza 
Published: May 2015

AbstractIn this study, interconnected porous bioactive scaffolds were synthesized for bone tissue engineering. At the first step, poly(
‐caprolactone) (PCL) diols were diacrylated with acryloyl chloride. Then, the scaffolds were synthesized by radical crosslinking reaction of PCL and poly(ethyleneglycol) (PEG) diacrylates in the presence of hydroxyapatite (HA) particles. Morphological, swelling, thermal, and mechanical characteristics as well as degradability of the scaffolds were investigated. Results showed that increasing the ratio of PEG to PCL led to significant increase of swelling ratio and degradation rate, and decrease of crystallinity and compressive modulus of the networks, respectively. It was found that the incorporation of HA particles with the polymer matrices resulted in an augmented crystallinity, a decreased swelling ratio, and also a significantly increased compressive modulus of the networks. Cytocompatability and osteoconductivity of the scaffolds were assessed by MTT and alkaline phosphatase (ALP) assays, respectively. The results confirmed the cytocompatible nature of PCL/PEG/HA scaffolds with no toxicity. MG‐63 cells attached and spread on the pore walls offered by the scaffolds. PCL/PEG/HA scaffolds compared with PCL/PEG ones showed higher ALP activity. Thus, the results indicated that the PCL/PEG/HA scaffolds have the potential of being used as promising substrates in bone tissue engineering. © 2015 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 103A: 3919–3926, 2015.
Bottom‐up topography assembly into 3Dporous scaffold to mediate cell activities
Authors: Cheng Delin , Hou Jie , Hao Lijing , Cao Xiaodong , Gao Huichang , Fu Xiaoling , Wang Yingjun 
Published: May 2015

AbstractNative cells live in a three‐dimensional (3D) extracellular matrix (ECM) capable of regulating cell activities through various physical and chemical factors. Designed topographies have been well proven to trigger significant difference in cell behaviours. However, present topographies are almost all constructed on two‐dimensional (2D) substrates like discs and films, which are far from features like 3D and porosity required in application like bone repair. Here we bottom‐up assembled poly(lactic‐co‐glycolic acid)/calcium carbonate (PLGA/CC) microspheres with superficial porous topography intactly into a 3D porous scaffold. Because the scaffold was obtained through a mild technique, the bioactivity of released BMP‐2 was well retained. Mouse bone marrow mesenchymal stem cells (mMSCs) were cultured on produced scaffolds having different 3D topographies. It turned out that osteogenic differentiation of mMSCs did respond to the 3D topographies, while proliferation didn't. Gene expression of αvand β1integrins revealed that adhesion was supposed to be the underlying mechanism for osteogenic response. The study provides insight into enhancing function of practical scaffolds by elaborate topography design. © 2015 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 104B: 1056–1063, 2016.
Combined unsupervised–supervised classification of multiparametric PET/MRI data: application to prostate cancer
Authors: Gatidis Sergios , Scharpf Markus , Martirosian Petros , Bezrukov Ilja , Küstner Thomas , Hennenlotter Jörg , Kruck Stephan , Kaufmann Sascha , Schraml Christina , la Fougère Christian , Schwenzer Nina F. , Schmidt Holger 
Published: May 2015

Multiparametric medical imaging data can be large and are often complex. Machine learning algorithms can assist in image interpretation when reliable training data exist. In most cases, however, knowledge about ground truth (e.g. histology) and thus training data is limited, which makes application of machine learning algorithms difficult.The purpose of this study was to design and implement a learning algorithm for classification of multidimensional medical imaging data that is robust and accurate even with limited prior knowledge and that allows for generalization and application to unseen data.Local prostate cancer was chosen as a model for application and validation. 16 patients underwent combined simultaneous [11C]‐choline positron emission tomography (PET)/MRI. The following imaging parameters were acquired: T2 signal intensities, apparent diffusion coefficients, parameters Ktrans and Kep from dynamic contrast‐enhanced MRI, and PET standardized uptake values (SUVs). A spatially constrained fuzzy c‐means algorithm (sFCM) was applied to the single datasets and the resulting labeled data were used for training of a support vector machine (SVM) classifier. Accuracy and false positive and false negative rates of the proposed algorithm were determined in comparison with manual tumor delineation. For five of the 16 patients rates were also determined in comparison with the histopathological standard of reference.The combined sFCM/SVM algorithm proposed in this study revealed reliable classification results consistent with the histopathological reference standard and comparable to those of manual tumor delineation. sFCM/SVM generally performed better than unsupervised sFCM alone. We observed an improvement in accuracy with increasing number of imaging parameters used for clustering and SVM training. In particular, including PET SUVs as an additional parameter markedly improved classification results.A variety of applications are conceivable, especially for imaging of tissues without easily available histopathological correlation. Copyright © 2015 John Wiley & Sons, Ltd.
On the convergence analysis, stability, and implementation of meshless local radial point interpolation on a class of three‐dimensional wave equations
Authors: Shivanian Elyas 
Published: May 2015

SummaryIn this article, the meshless local radial point interpolation method is applied to analyze three space dimensional wave equations of the form
subject to given initial and Dirichlet boundary conditions. The main difficulty of the great number of methods in full 3‐D problems is the large computational costs. In meshless local radial point interpolation method, it does not require any background integration cells, so that all integrations are carried out locally over small quadrature domains of regular shapes such as circles or squares in two dimensions and spheres or cubes in three dimensions. The point interpolation method with the help of radial basis functions is proposed to construct shape functions that have Kronecker delta function property. A weak formulation with the Heaviside step function converts the set of governing equations into local integral equations on local subdomains. A two‐step time discretization method is employed to evaluate the time derivatives. This suggests Crank‐Nicolson technique to be applied on the right hand side of the equation. The convergence analysis and stability of the method are fully discussed. Three illustrative examples are presented, and satisfactory agreements are achieved. It is shown theoretically that the proposed method is unconditionally stable for the second example whereas it is not for the first and third ones. Copyright © 2015 John Wiley & Sons, Ltd.
Lifestyle and weight predictors of a healthy overweight profile over a 20‐year follow‐up
Authors: Fung Michael D.T. , Canning Karissa L. , Mirdamadi Paul , Ardern Chris I. , Kuk Jennifer L. 
Published: May 2015

ObjectiveTo examine whether changes in modifiable risk factors [physical activity, cardiorespiratory fitness (CRF), body weight, and diet composition] are associated with the transition to metabolically healthy overweight/obese (MHOW) versus metabolically abnormal overweight/obese.MethodsAnalysis included 1,358 adults [aged 25.0 (3.5) years] from the CARDIA study who were healthy at baseline and had overweight/obesity at follow‐up. Participants with zero or one of the following six risk factors were classified as MHOW: elevated triglycerides, LDL, blood pressure, fasting glucose, and HOMA‐insulin resistance and low HDL.ResultsOver the 20‐year follow‐up, the sample gained weight (BMI 24.5 to 31.1 kg/m2), and the prevalence of MHOW was 47% at follow‐up. After adjusting for changes in CRF, diet, and weight change, physical activity and macronutrient intake were not independently associated with MHOW (P > 0.05), while changes in CRF [fit–unfit: RR (95%) = 0.58, 0.52‐0.66; unfit–unfit: RR = 0.67, 0.58‐0.76, versus fit–fit] and weight [gain: RR (95%) = 0.54, 0.43‐0.67; cycle: RR = 0.74, 0.57‐0.94, versus stable] were independently associated with MHOW.ConclusionsFocusing on high CRF and strategies to limit weight gain may be important for individuals with overweight and obesity in early to mid‐adulthood to maintain a metabolically healthy profile.
Seeing Beyond the Visible
Authors: Hashagen Jens 
Published: May 2015

AbstractShort‐wave infrared (SWIR) cameras open up numerous possibilities for machine vision solutions, since they detect invisible product flaws as well as desired characteristics: In contrast to mainstream machine vision cameras with CCD or CMOS sensors, most SWIR cameras have an InGaAs (Indium Gallium Arsenide) sensor and thus detect wavelengths between 900 nm and 1700 nm. These wavelengths are invisible to the human eye and CCD or CMOS cameras. Thus, SWIR cameras detect the invisible, for example, water accumulations inside fruits or defects within silicon products. This document gives examples of SWIR camera applications in several fields such as the semiconductor industry, recycling, metal and glass inspection, and airborne remote sensing. Since some SWIR cameras are mainly designed for use in research facilities, not only the image quality is crucial for industrial applications, but also an industrial rugged design as well as camera features commonly used in machine vision applications.