bluuebunny/crossref_metadata_2025_split huggingface dataset:
DNA‐based identification of Calendula officinalis (Asteraceae)
Authors: Schmiderer Corinna , Lukas Brigitte , Ruzicka Joana , Novak Johannes 
Published: November 2015

Premise of the study:For the economically important species Calendula officinalis, a fast identification assay based on high‐resolution melting curve analysis was designed. This assay was developed to distinguish C. officinalis from other species of the genus and other Asteraceae genera, and to detect C. officinalis as an adulterant of saffron samples.Methods and Results:For this study, five markers (ITS, rbcL, 5′ trnK‐matK, psbA‐trnH, trnL‐trnF) of 10 Calendula species were sequenced and analyzed for species‐specific mutations. With the application of two developed primer pairs located in the trnK 5′ intron and trnL‐trnF, C. officinalis could be distinguished from other species of the genus and all outgroup samples tested. Adulterations of Calendula DNA in saffron could be detected down to 0.01%.Conclusions:With the developed assay, C. officinalis can be reliably identified and admixtures of this species as adulterant of saffron can be revealed at low levels.
Les infections par Toxoplasma Gondii chez les mammifères marins échoués sur les côtes françaises et roumaines
Authors: Le Corre Anne-Claire 
Published: November 2015

Toxoplasma gondii infections in stranded marine mammals in France and Romania.
Marine mammals are major sentinel species for the research concerning contamination of marine environment by terrestrial pathogens and are early warnings for the emergence or resurgence of infectious diseases. Protozoal parasites such as Toxoplasma gondii and Sarcocystis spp. and the helminth parasites Trichinella spp. can infect many species of marine mammals worldwide. T. gondii and Trichinella spp. zoonotic infections are a matter of concern for human health, because consumption of marine mammal meat is frequent in some regions of the world.
Extensive seroprevalence investigations have been made in some parts of the world, showing a high presence of T. gondii infections in marine animals, yet little is known about it in France and Romania. This study indicates the exposure of cetaceans and pinnipeds from France and Romania to T. gondii and should be pursued by large-scale studies. This is the first report on the detection of T. gondii
antibodies in cetaceans and seals in France and Romania and the first identification of T. gondii in a sperm whale.
Tracking access, utilization and health system responsiveness to inform evidence-based health care policy: The case of Qatar
Authors: Hussin Altijani H. , Ali Faleh M.H. , Reka Husein , Gjebrea Orsida 
Published: November 2015

Background: From 2004 to 2010, the population of Qatar increased by 128%, from 744,029 to 1,699,435 inhabitants. This sharp rise in population led to declines in per-capita health care personnel and hospital bed capacity. Aims and objectives: To examine patient and provider characteristics associated with health system performance measures, the variation in these measures between Qataris and non-Qataris, and whether these measures have changed over time. Methods: We examine access, utilization, health system responsiveness and satisfaction measures, using multivariate regression analysis based on health surveys from 2006 and 2010. For purposes of representativeness, 2006 analysis applied population weights, and 2010 analysis applied weights constructed by using age, gender, nationality and occupation, based on the 2010 Census. Results: For access, we find no differences between Qataris and non-Qataris in the probability of having a usual source of care (USC). For utilization, Qatari women are 67% more likely than non-Qatari women to have an inpatient stay; both Qatari men and women are more likely to have any outpatient visits (48% and 35%) compared to non-Qataris. For health system responsiveness, for outpatient care, those who go to private clinics report higher ratings than those who go to Primary Health Care Corporation (PHCC) centers in 2006. Those who go to private clinics, private hospitals and other/employer clinics report higher ratings than those who go to PHCC centers in 2010. For satisfaction with the health care system, non-Qataris are twice as likely as Qataris to report high satisfaction in 2006. Conclusions: We find that satisfaction with outpatient services for public providers is lower than ratings for private providers, most significantly for waiting times (odd ratio of 1.20 [0.15] vs. 0.77 [0.08]). For satisfaction with the health care system, non-Qataris are twice as likely as Qataris to report high satisfaction; although for access, we find no difference between Qataris and non-Qataris in the probability of having a USC.
Policy implications include improving public services, increasing provider capacity and improving access to private providers. In addition, a major policy action was the launch of a mandatory social health insurance scheme in 2013, which enabled choice of provider and access to public and private providers. As such, increased provider capacity, public private partnerships, and competition between public and private providers are likely to improve services among public providers, including waiting times.
Blood Samples of Peripheral Venous Catheter or The Usual Way: Do Infusion Fluid Alters the Biochemical Test Results?
Authors: Taghizadeganzadeh Mahboobeh , Yazdankhahfard Mohammadreza , Farzaneh Mohammadreza , Mirzaei Kamran 
Published: November 2015

<p><strong>BACKGROUND:</strong> Most blood tests require venous blood samples. Puncturing the vein also causes pain, infection, or damage to the blood, and lymph flow, or long-term healing. This study aimed to determine and compare the biochemical laboratory value of the blood samples that were provided through: peripheral vein infusion (PVI) receiving continuous intravenous fluid; and the usual method of blood sampling.</p><p><strong>METHODS</strong><strong>:</strong> This is an interventional, quasi-experimental, and controlled study. The selected study sample included 60 patients, who were hospitalized during 2014, in the Internal Medicine, part of Martyrs of Persian Gulf, teaching hospital at Bushehr. Three blood samples were taken from each patient that were provided through PVI line (5 ml blood collected at beginning of IVC and then another 5 cc), and another case was prepared by common blood sampling (control). All the samples were analyzed in terms of sodium, potassium, urea and creatinine using SPSS Ver.19 software, by paired <em>t</em>-test and Pearson's correlation coefficients.</p><p><strong>RESULTS:</strong> There was a statistically significant difference between the amount of sodium and potassium in the first blood samples taken from the intravenous infusion line and vein puncture .However, no significant differences were found among the biochemical amount in the second blood samples taken from the intravenous infusion line and vein puncture. </p><p><strong>CONCLUSIONS: </strong>We can use blood samples taken from peripheral intravenous infusion lines after 5cc discarding from the first part of the sample for measuring the value of sodium, potassium, urea and creatinine. </p>
Next-Generation Sequencing of Matched Primary and Metastatic Rectal Adenocarcinomas Demonstrates Minimal Mutation Gain and Concordance to Colonic Adenocarcinomas
Authors: Crumley Suzanne M. , Pepper Kristi L. , Phan Alexandria T. , Olsen Randall J. , Schwartz Mary R. , Portier Bryce P. 
Published: November 2015

Context.—Colorectal carcinoma is the third most common cause of cancer death in males and females in the United States. Rectal adenocarcinoma can have distinct therapeutic and surgical management from colonic adenocarcinoma owing to its location and anatomic considerations.
Objective.—To determine the oncologic driver mutations and better understand the molecular pathogenesis of rectal adenocarcinoma in relation to colon adenocarcinoma.
Design.—Next-generation sequencing was performed on 20 cases of primary rectal adenocarcinoma with a paired lymph node or solid organ metastasis by using an amplicon-based assay of more than 2800 Catalogue of Somatic Mutations in Cancer (COSMIC)–identified somatic mutations.
Results.—Next-generation sequencing data were obtained on both the primary tumor and metastasis from 16 patients. Most rectal adenocarcinoma cases demonstrated identical mutations in the primary tumor and metastasis (13 of 16, 81%). The mutations identified, listed in order of frequency, included TP53, KRAS, APC, FBXW7, GNAS, FGFR3, BRAF, NRAS, PIK3CA, and SMAD4.
Conclusions.—The somatic mutations identified in our rectal adenocarcinoma cohort showed a strong correlation to those previously characterized in colonic adenocarcinoma. In addition, most rectal adenocarcinomas harbored identical somatic mutations in both the primary tumor and metastasis. These findings demonstrate evidence that rectal adenocarcinoma follows a similar molecular pathogenesis as colonic adenocarcinoma and that sampling either the primary or metastatic lesion is valid for initial evaluation of somatic mutations and selection of possible targeted therapy.
Estudio de las Competencias Socio Emocionales y su Relación con el Afrontamiento en Futuros Profesores de Nivel Medio.
Authors: Cassullo Gabriela Livia , García Livia 
Published: November 2015

<p>Profundizar en el estudio de los aspectos psicosociales referidos a las competencias socioemocionales y considerar las relaciones existentes con el afrontamiento, en tanto recursos para afrontar la adversidad con éxito, es un desafío apasionante para la investigación con futuros docentes que deberán integrarse a contextos educativos y afrontar múltiples situaciones estresantes surgidas de la tarea misma. Los profesores se enfrentan a sucesos vitales estresantes que según la literatura se visualizan en la violencia, exclusión social, la conflictividad familiar y la incapacidad de la escuela para compensar las carencias y desigualdades, entre otros.Cuando se habla de inteligencia emocional en el contexto educativo no se puede dejar de lado el importante papel del profesorado en este campo.</p><p>Este estudio se propone analizar las competencias socioemocionales instrumentadas por los futuros profesores del Instituto Superior del Profesorado Superior J.V. González de la Ciudad Autónoma de Buenos Aires, Argentina, al afrontar estresores vitales específicos a la práctica docente.<strong></strong></p>
Au travers de la représentation du témoignage
Authors: Pouliot Étienne 
Published: November 2015

On convient aisément que tout témoignage peut renvoyer à une expérience, passée ou du moins présupposée, ou encore qu’il peut véhiculer en quelque sorte un message. Il ne se réduit pas pour autant à n’être qu’une fenêtre sur autre chose, voire sur lui-même. En vérité, parce qu’il est avant tout parole, le témoignage constitue toujours et se constitue précisément en un certain ratage de l’expérience là représentée, du message là livré, du vécu là offert. Un examen de certaines conditions épistémologiques de cet enjeu de la représentation au coeur du témoignage, en écho à la philosophie de Paul Ricoeur mais pour en signaler le point aveugle, permet d’élucider que cet enjeu y est second — ce qui ne signifie en rien : secondaire — par rapport à un enjeu herméneutique bien plus originaire, bien plus radical et fondamental que la représentation elle-même : celui de (l’acte de) la parole. Au travers du témoignage, une parole (s’)atteste autant qu’elle (s’)efface.
Peut-on témoigner tout en dormant ?
Authors: Nault François 
Published: November 2015

Quand on évoque le sommeil des apôtres au jardin de Gethsémani, c’est généralement pour souligner la faiblesse des amis de Jésus, qui n’ont pas eu le courage de veiller avec lui, au moment où il en avait manifestement bien besoin. Mais le sommeil des apôtres ne pourrait-il pas être interprété plus positivement : comme un témoignage plutôt qu’une trahison ? Ainsi l’auteur de cet article cherche à montrer que le sommeil peut nous faire avancer dans la compréhension de ce que l’on appelle « témoignage ». En outre, il suggère que le sommeil en tant que tel peut constituer un témoignage chrétien, qu’il est même peut-être le plus beau témoignage que l’on puisse faire, dès lors justement qu’en dormant on ne fait rien.
Fluid Driven Membrane Actuation for Reconfigurable Acoustic Manipulation
Authors: Choi Christabel , Hardwick James , Bansal Shubhi , Subramanian Sriram 
Published: August 2024

AbstractAcoustic metamaterials based on out‐of‐plane actuation can flexibly reconfigure arrayed unit cells on demand, to shape sound fields for applications such as beam formation or holography. However, implementing active reconfiguration on the millimeter‐scale is challenging, due to the lack of suitable actuation methods. Besides electronic complexity, current methods suffer from limited actuation range (sub‐millimeter), and discrete steps inhibit smooth sound modulation. Here, a novel fluid‐driven approach for continuous out‐of‐plane actuation is presented. A three dimensionally (3D)‐printed fluidic chip is integrated with an elastomeric membrane, and selective inflation of membrane sections actuates acoustic reflector unit cells according to their shape and position. The compact device enables displacements >5 mm without coupling mechanisms or external power. It is experimentally demonstrate single‐channel and multi‐channel prototypes, including an ultrasonic metasurface built for controllable acoustic focusing at five different locations. The fluidic chips are monolithically printed via digital light processing without internal support material, and the membranes are fabricated by accessible and cost‐effective spacer‐based fabrication. The methods are reproducible and eliminate complex processes (e.g., adhesion of layers) commonly associated with multi‐layered micro/milli fluidic devices. The outlined approaches and concepts in this work can be applied beyond the field of metamaterials, such as for visual displays, or tactile devices.
Light‐Broadened Faradaic Regime of Organic Electrochemical Transistors for Accelerated Amperometric Biodetection
Authors: Ju Peng , Jiang Xingwu , Xu Yi‐Tong , Hu Jin , Chi Jingtian , Jiang Tiantong , Lu Zhaoxia , Zhai Xiaofan , Zhao Wei‐Wei 
Published: August 2024

AbstractFaradaic‐mode organic electrochemical transistors (OECT) are promising but usually need hundreds of millivolts to sustain redox reactions. Decrease or even removal of the voltage penalty is highly desirable. Herein, the Faradic regime of the OECT is broadened toward zero bias by integrating a p‐n heterojunction of Cu2S‐diethylenetriamine (DETA)‐CdS for efficient photogating of poly(3,4‐ethylenedioxythiophene): poly(styrene sulfonate) channel. Upon light illumination, it is found that an obvious Faradaic process is evolved at the gate/electrolyte interface under zero gate bias, suggesting the potential of sensitive amperometric biodetection with enhanced signal resolution. At the Cu2S‐DETA‐CdS/liquid interface, a biosensing process is introduced, combining with a DNA walker and enzymatic biocatalytic precipitation to produce a target‐dependent diffusion barrier, modulating the amperometric output with enhanced signal variations under light irradiation compared to that in the dark. The proposed system achieves the desired analytical performance for representative target miRNA‐10b with a low detection limit of 0.21 fM. This work features a light‐mediated OECT device with enhanced signal resolution and provides new operational paradigms and insights for novel optoelectronics interfacing with biological systems.
Recent Advances in Cathode Materials with Core–Shell Structures and Concentration Gradients for Advanced Sodium‐Ion Batteries
Authors: Hou Peiyu , Dong Mohan , Li Feng , Lin Zezhou , Xu Xijin 
Published: August 2024

AbstractSodium‐ion batteries (SIBs) offer excellent potential for meeting the urgent need to develop low‐cost and durable large‐scale electrical energy storage systems. However, the electrochemical performance of currently available SIBs requires substantial improvement to enable their practical deployment. The cathode material is one of the greatest factors impacting SIB performance. The recent development of cathodes with core–shell structures and concentration gradients offers considerable promise for addressing these issues limiting the implementation of SIBs. Therefore, this review presents the primary factors affecting the development of these advanced cathode materials. First, the study discusses recently developed methods for preparing these materials, including precipitation reactions, ion‐exchange reactions, and doping induction. The study further summarizes recent advances in developing layered transition‐metal oxides, poly‐anionic compounds, Prussian blue analogs, organic molecules, and other cathodes with core–shell structures and concentration gradients. Moreover, the state of understanding regarding the Na storage mechanisms of these heterogeneous cathodes is also presented. Finally, the remaining major challenges restricting the development of these cathode structures are discussed and possible solutions are provided. This review also enables the heterogeneous concepts to be expanded to high‐capacity anodes employed in alkali metal ion batteries.
Dual‐direction Circularly Polarized Luminescence Materials With On‐demand Handedness and Superior Flexibility
Authors: Jia Shengzhe , Yang Bingbing , Xie Yujiang , Tao Tiantian , Du Jing , Yu Liuyang , Zhang Yuan , Zhang Jiayin , Tang Weiwei , Gong Junbo 
Published: August 2024

AbstractThis work utilizes the self‐assembled cellulose nanocrystals (CNCs) as the host chiral template and fabricates a circularly polarized luminescence (CPL) film. By manipulating the photonic bandgap, the synthesized film integrates a strong CPL signal and superior mechanical flexibility. Without losing the CPL activity, the ultimate strain of 19% has exceeded most CNC‐based chiral luminescent assemblies, which enables them candidates in the optical sensor and wearable device. Meanwhile, the film has a humidity‐stimulus CPL response, with the dissymmetry factor (glum) close to 0.51. This responsive process is reversible and the optical properties can recover upon drying. Next, by manipulating the optical pathway, this work achieves on‐demand CPL direction control and meets the considerable intensity of reversed optical signals (glum: ‐0.35), avoiding the structure disruption and direction random under the external stimuli, which opens a new insight into the optical regulations. Furthermore, this work combines the in situ growth strategy and first synthesizes the dynamic‐switchable dual‐direction CPL film. Optics in both directions can be inverted simultaneously by exchanging the growth sequences. Finally, multimodal optics, excellent stability, and green manufacturing make them welcome in the advanced anti‐counterfeit areas, with the features of lossless and long‐time useful.
Textured RuIrAgMnO2 Oxides With Preferentially Orientated (110) Facet by Concerted Shaping of Ag and Mn for Stable Acid Water Oxidation
Authors: Zhang Ming , Sun Yanhui , Liu Feng , Gan Jun , Gao Shixin , Liu Jingjun 
Published: August 2024

AbstractEntropy‐based polymetallic oxides with configurational entropy, structure flexibility, and crystallographic orientation have been regarded as promising catalysts for oxygen evolution reaction (OER), due to their electronic energy band occupation, composition ligand stabilization, and “cocktail” effect. Herein, a rutile RuIrAgMnO2 oxide with an orientation along the (110) facets is first fabricated by a low‐temperature directional co‐pyrolysis strategy of metal salts on Ti foil at 300 °C. The quaternary oxide exhibits a texture coefficient of 1.13 along (110) facet, resulting from concerted shaping of Ag and Mn components presenting a vibrational entropy of 1.13 R (R is the gas content). In 0.5 m H2SO4, it displays an overpotential of 171 mV at 10 mA cm−2 for OER, running at a voltage for 340 h at 100 mA cm−2. The remarkably improved performance can be associated with the presence of the preferred (110) facets with in‐plane strains, which activate and stabilize OER process via electronic energy band reconstruction. More interestingly, the preferential orientation prevents the diffusion or dissolution of active metal ions caused by entropy‐dependent energy barriers, ensuring long‐term stability. This work can pave the way for entropy‐driven polymetallic oxides with optimal structures, disrupting the trade‐off between activity and stability in water oxidation.
Dynamic and Static Workout of In Vitro Skeletal Muscle Tissue through a Weight Training Device
Authors: Jo Byeongwook , Motoi Kentaro , Morimoto Yuya , Takeuchi Shoji 
Published: August 2024

AbstractEnhancing muscle strength through workouts is a key factor in improving physical activity and maintaining metabolic profiles. The controversial results concerning the impacts of weight training often arise from clinical experiments that require controlled experimental conditions. In this study, a weight training system for a muscle development model is presented, which is capable of performing weight training motions with adjustable weight loads. Through the implementation of cultured skeletal muscle tissue with floating structures and a flexible ribbon, both isotonic (dynamic change in muscle length) and isometric (static in muscle length) exercises can be performed without the deflection of the tissue. Quantitative analysis of contraction force, changes in metabolic processes, and muscle morphology under different weight training conditions demonstrates the effectiveness of the proposed system. Our proposed system holds potential for establishing effective muscle development and for further applications in rehabilitation training methods.
3D Soft Architectures for Stretchable Thermoelectric Wearables with Electrical Self‐Healing and Damage Tolerance
Authors: Han Youngshang , Tetik Halil , Malakooti Mohammad H. 
Published: August 2024

AbstractFlexible thermoelectric devices (TEDs) exhibit adaptability to curved surfaces, holding significant potential for small‐scale power generation and thermal management. However, they often compromise stretchability, energy conversion, or robustness, thus limiting their applications. Here, the implementation of 3D soft architectures, multifunctional composites, self‐healing liquid metal conductors, and rigid semiconductors is introduced to overcome these challenges. These TEDs are extremely stretchable, functioning at strain levels as high as 230%. Their unique design, verified through multiphysics simulations, results in a considerably high power density of 115.4 µW cm⁻2 at a low‐temperature gradient of 10 °C. This is achieved through 3D printing multifunctional elastomers and examining the effects of three distinct thermal insulation infill ratios (0%, 12%, and 100%) on thermoelectric energy conversion and structural integrity. The engineered structure is lighter and effectively maintains the temperature gradient across the thermoelectric semiconductors, thereby resulting in higher output voltage and improved heating and cooling performance. Furthermore, these thermoelectric generators show remarkable damage tolerance, remaining fully functional even after multiple punctures and 2000 stretching cycles at 50% strain. When integrated with a 3D‐printed heatsink, they can power wearable sensors, charge batteries, and illuminate LEDs by scavenging body heat at room temperature, demonstrating their application as self‐sustainable electronics.