bluuebunny/crossref_metadata_2025_split huggingface dataset:
Allocating Limited Surveillance Effort for Outbreak Detection of Endemic Foot and Mouth Disease
Authors: Greiner Ariel , Herrera-Diestra José Luis , Tildesley Michael , Shea Katriona , Ferrari Matthew 
Published: August 2024

AbstractFoot and Mouth Disease (FMD) affects cloven-hoofed animals globally and has become a major economic burden for many countries around the world. Countries that have had recent FMD outbreaks are prohibited from exporting most meat products; this has major economic consequences for farmers in those countries, particularly farmers that experience outbreaks or are near outbreaks. Reducing the number of FMD outbreaks in countries where the disease is endemic is an important challenge that could drastically improve the livelihoods of millions of people. As a result, significant effort is expended on surveillance; but there is a concern that uninformative surveillance strategies may waste resources that could be better used on control management. Rapid detection through sentinel surveillance may be a useful tool to reduce the scale and burden of outbreaks. In this study, we use an extensive outbreak and cattle shipment network dataset from the Republic of Türkiye to test three possible strategies for sentinel surveillance allocation that differ in their data requirements: ranging from low to high data needs, we allocate limited surveillance to [1] farms that frequently send and receive shipments of animals (Network Connectivity), [2] farms near other farms with past outbreaks (Spatial Proximity) and [3] farms that receive many animals from other farms with past outbreaks (Network Proximity). We determine that all of these surveillance methods find a similar number of outbreaks – 2-4.5 times more outbreaks than were detected by surveying farms at random. On average across surveillance efforts, the Network Proximity and Network Connectivity methods each find a similar number of outbreaks and the Spatial Proximity method always finds the fewest outbreaks. Since the Network Proximity method does not outperform the other methods, these results indicate that incorporating both cattle shipment data and outbreak data provides only marginal benefit over the less data-intensive surveillance allocation methods for this objective. We also find that these methods all find more outbreaks when outbreaks are rare. This is encouraging, as early detection is critical for outbreak management. Overall, since the Spatial Proximity and Network Connectivity methods find a similar proportion of outbreaks, and are less data-intensive than the Network Proximity method, countries with endemic FMD whose resources are constrained could prioritize allocating sentinels based on whichever of those two methods requires less additional data collection.
A genome-wide screen inex vivogallbladders identifiesListeria monocytogenesfactors required for virulencein vivo
Authors: Schwardt Nicole H. , Halsey Cortney R. , Sanchez Madison E. , Reniere Michelle L. 
Published: August 2024

ABSTRACTListeria monocytogenesis a Gram-positive pathogen that causes the severe foodborne disease listeriosis. Following oral infection of the host,L. monocytogenesdisseminates from the gastrointestinal tract to peripheral organs, including the gallbladder, where it replicates to high densities. The gallbladder then becomes the primary bacterial reservoir and source of fecally excreted bacteria. Despite its importance in pathogenesis, little is known about howL. monocytogenessurvives and replicates in the gallbladder. In this study, we assessed theL. monocytogenesgenes required for growth and survival inex vivonon-human primate gallbladders using a transposon sequencing approach. The screen identified 43 genes required for replication in the gallbladder, some of which were known to be important for virulence, and others had not been previously studied in the context of infection. We evaluated the roles of 19 genes identified in our screen bothin vitroandin vivo, and demonstrate that most were required for replication in bilein vitro, for intracellular infection of murine cells in tissue culture, and for virulence in an oral murine model of listeriosis. Interestingly, strains lacking the mannose phosphoenolpyruvate-dependent phosphotransferase system (PTS) permeases Mpt and Mpo exhibited no defects in intracellular growth or intercellular spread but were significantly attenuated during murine infection. While the roles of PTS systemsin vivowere not previously appreciated, these results suggest that PTS permeases are necessary for extracellular replication during infection. Overall, this study demonstrates thatL. monocytogenesgenes required for replication in the gallbladder also play broader roles in disease.
Lower degree of microsatellite instability in colorectal carcinomas fromMSH6-associated Lynch syndrome patients
Authors: Helderman Noah C. , Strobel Fabian , Bohaumilitzky Lena , Terlouw Diantha , van der Werf – ′t Lam Anne-Sophie , van Wezel Tom , Morreau Hans , von Knebel Doeberitz Magnus , Nielsen Maartje , Kloor Matthias , Ahadova Aysel 
Published: August 2024

AbstractBackgroundNumerous observational and molecular studies focusing on Lynch syndrome (LS) have revealed significant variation in the phenotype and molecular characteristics among carriers of pathogenic variants in mismatch repair genes (path_MMR). Recently, we demonstrated that colorectal carcinomas inpath_MSH6carriers exhibit fewer insertion/deletion mutations compared to CRCs from other MMR groups, raising the question of whetherMSH6-mutated CRCs might display a lower degree of microsatellite instability (MSI).MethodsMutations at twenty coding microsatellites (cMS) were analyzed in 39MSH6-, 18MLH1-, 16MSH2- and 22PMS2-mutated CRCs and 35 sporadic MSI CRCs, and mutation frequencies and mutant allele ratios were compared among the different MMR-deficient groups. Considering factors such asHLA-A*02:01 type,B2Mstatus, and the anticipated immunogenicity of frameshift peptides derived from cMS mutations, the identified cMS mutation profiles ofMSH6-mutated CRCs were further investigated to assess their potential impact on immunotherapeutic strategies.ResultsMSH6-mutated CRCs exhibited lower mutation frequencies and mutant allele ratios across most cMS. The cMS mutations inMSH6-mutated CRCs demonstrated inverse correlations with the predicted immunogenicity of the resulting frameshift peptides, which may suggest negative selection of cell clones bearing highly immunogenic frameshift peptides.ConclusionsMSH6-mutated CRCs display a lower degree of MSI, which may be connected to lower penetrance and later onset of the disease inpath_MSH6carriers. Moreover, this lower MSI level may implicate an altered immune response compared to other MSI CRCs, which could have implications for the success of immunotherapy inMSH6-mutated CRCs. Future studies should carefully evaluate this possibility. If confirmed, these results would reinforce the notion of classifying LS as distinct syndromes associated with specific MMR genes.
Testing for Markovian character of transfer of fluctuations in solar wind turbulence on kinetic scales
Authors: Wójcik Dariusz , Macek Wiesław M. 
Published: August 2024

We apply statistical analysis to search for processes responsible for turbulence in physical systems. In our previous studies, we have shown that solar wind turbulence in the inertial range of large magnetohydrodynamic scales exhibits Markov properties. We have recently extended this approach on much smaller kinetic scales. Here we are testing for the Markovian character of stochastic processes in a kinetic regime based on magnetic field and velocity fluctuations in the solar wind, measured onboard the Magnetospheric Multiscale (MMS) mission: behind the bow shock, inside the magnetosheath, and near the magnetopause. We have verified that the Chapman-Kolmogorov necessary conditions for Markov processes is satisfied for transfer of energy between the magnetic and velocity fields also on kinetic scales. We have confirmed that for magnetic fluctuations, the first Kramers-Moyal coefficient is linear, while the second term is quadratic, corresponding to drift and diffusion processes in the resulting Fokker-Planck equation. It means that magnetic self-similar turbulence is described by generalized Ornstein-Uhlenbeck processes. We show that for the magnetic case, the Fokker-Planck equation leads to the probability density functions of the kappa distributions, which exhibit global universal with a linear scaling and lack of intermittency. On the contrary, for velocity fluctuations, higher order Kramers-Moyal coefficients should be taken into account and hence scale invariance is not observed. However, the nonextensity parameter in Tsallis entropy provides a robust measure of the departure of the system from equilibrium. The obtained results are important for a better understanding of the physical mechanism governing turbulent systems in space and laboratory.

Published by the American Physical Society
2024
The effect of a trampoline exercise program on motor and behavioral characteristics of adolescents with autism spectrum disorder
Authors: Giagazoglou Paraskevi , Kannas Theodoros , Dampa Athanasia , Iliopoulou Stalakti , Alivizatou Ioulia , Chalatzoglidis Georgios 
Published: August 2024

Purpose
The aim of this study is to evaluate the impact of a trampoline intervention program on motor and behavioral characteristics of adolescents with autism spectrum disorder (ASD).

Design/methodology/approach
Twenty-six male students aged 15–18 years with ASD participated in the study. They were equally divided into two groups of 13 students. The intervention group followed an individualized trampoline exercise program that was applied three times a week for 30 min for 12 weeks. Before the intervention program and after the end of this, the motor performance was evaluated through the recording of the total number of jumps. The behavioral characteristics were evaluated with the Behavior Problem Inventory questionnaire.

Findings
According to the findings, there were statistically significant differences between the intervention group and the control group across all variables. In conclusion, it seems that an intervention program with the use of a trampoline, adapted to the needs and capabilities of adolescents with ASD can improve their motor performance and behavioral characteristics.

Originality/value
The authors report on the impact of a trampoline exercise program on motor skills and behavioral traits in adolescents diagnosed with ASD. This is significant because our research focused on investigating the effects of a structured trampoline exercise program both on motor skills and behavioral characteristics. The findings contribute to the growing body of evidence supporting targeted exercise programs as effective interventions for addressing motor and behavioral challenges in adolescents with ASD. The authors believe the research aligns closely with the aims and scope of research in developmental disabilities, and the authors hope that it will make a meaningful impact on the field of autism research and intervention.
Collaborative online shopping: customer satisfaction and the influence of product type, gender and involvement
Authors: Li Jia , Yen David C. , Zhang Pengzhu , Liu Xuan 
Published: August 2024

PurposeOnline shopping has recently been evolving more toward the subject area of collaborative online shopping (COS), and customer satisfaction is one of the key determinants for the success of COS. In this study, we investigate the effect of product type and gender and their interaction with customer satisfaction through user involvement in a collaborative online shopping context.Design/methodology/approachWe developed a lab experiment with a mixed two-by-two factorial design to test the proposed research model. We chose gender (male versus female) as the between-subjects factor and product type (utilitarian product versus hedonic product) as the within-subjects factor.FindingsThe obtained results indicate that collaborative shopping may require group members to be more involved for a hedonic product than a utilitarian product. When collaboratively shopping for utilitarian products, male groups tend to show a higher level of involvement than female groups. In contrast, female groups show a higher level of involvement than male groups when collaboratively shopping for hedonic products. Furthermore, our results indicate that greater involvement in COS may lead to higher satisfaction.Social implicationsWebsites that sell hedonic products should first adopt the design elements that support COS. Meanwhile, online sellers should be aware that the gender gap still exists as online shopping evolves toward social online shopping. In addition, COS websites should provide more design elements (e.g. co-browsing, avatar embodiment, video chat and voting tools) to stimulate user involvement.Originality/valueIn this paper, we employ the theory of consumption values, which decomposes COS value into the utilitarian and hedonic dimensions, as a theoretical foundation to investigate the effect of product type and gender together as well as their interactions in the COS context. The obtained findings may provide various insights and empirical evidence to improve the understanding of how to target male and female customers across different product types in the COS context.
Does social media marketing important for MSMEs performance in Indonesia?
Authors: Tatik Tatik , Setiawan Doddy 
Published: August 2024

PurposeThis study aims to examine the main factors that influence the adoption of social media marketing (SMM) by small and medium-sized enterprises (SMEs) in Indonesia and how the influence of social media marketing on the performance of micro, small and medium-sized enterprises (MSMEs) in Indonesia. This research can provide input for teaching, public policy toward digital infrastructure and influence public attitudes toward digital involvement in business. This implication is in line with the findings of this research, which bridges theory and practice and has the potential to influence economic growth and quality of life.Design/methodology/approachThe data collection method used is a survey method by distributing questionnaires to MSME actors. The number of samples in this study was 234 respondents. This study was analyzed using the Structural Equation Model (SEM) with the help of SmartPLS software.FindingsThe results of this study indicate that marketing through social media has an effect on the performance of MSMEs. MSMEs need to adopt digital media considering the rapid development of digital technology today to be in line with the demands of business development. Using social media platforms, consumers can instantly connect with new products, services and brands with ease.Originality/valueThis article provides a significant and original contribution to the literature by examining the influence of social media marketing on the performance of micro, small and medium-sized enterprises (MSMEs) in Indonesia. This report provides new insights into the adoption and impact of SMM in the Indonesian context, where internet and social media use is very high.
Exploring the nexus between influencers and brand evangelism
Authors: Sharma Purvendu , Khandeparkar Kapil 
Published: August 2024

PurposeThis study investigates the antecedents that nudge followers of social media (SM) influencers into brand evangelism (BE). In doing so, we study how influencer-related attributes such as their homophily, trust, and popularity impact their followers’ BE. Additional interlinkages pertaining to popularity, content, warmth, and prestige are examined, impacting BE.Design/methodology/approachA cross-sectional survey obtained information about the focal constructs from 206 participants. Quantitative procedures using partial least square-based structural equation modeling were implemented to analyze the collected data and the proposed relationships.FindingsThe findings indicate homophily’s role in influencing trust, content, and prestige. BE is developed through warmth and content, whereas trust and prestige inspire warmth. Further, an influencer’s popularity impacts homophily and content. Lastly, the mediating role of warmth, homophile, trust, exciting content, and prestige advances the understanding of influencers and BE.Research limitations/implicationsWe converge literature from branding, influencer marketing, and social psychology to understand consumers' facets of promoting BE on SM. This work is a primary attempt to interlink and tie these crucial research streams together.Practical implicationsThe study offers managers helpful guidance on strategically assessing influencers' traits to build BE. Additionally, recommendations for tactically assessing and engaging influencers for brands are offered.Originality/valueThis is the first study to identify influencer-related parameters contributing to BE. Secondly, we study unique drivers such as homophily, trust, and warmth, which are important yet remain unexplored as far as BE in influencer marketing is concerned. Furthermore, this study also highlights the mediating role of key constructs that possess a potential to strengthen consumer brand relationships.
The influence of urban campus landscape on college students' exercise participation and mental health: an approach using deep learning and street view images
Authors: Zheng Zhenhua , Chen Linquan , Zeng Min , Liu Wanting , Chen Hong 
Published: August 2024

PurposeCollege student’s mental health issues have emerged as a significant public health concern. The urban campus environment, being the primary habitat for college students, plays a crucial role in influencing their mental health.Design/methodology/approachBased on survey data from 34 Chinese universities and 1173 college students in 2021, this study utilized deep learning and street view images to explore the relationship between various urban campus landscapes, college students' exercise participation, and mental health.FindingsThe study revealed substantial variations in campus landscape features, particularly in terms of spatial openness. While green campus landscapes (measured by the Green View Index and Normalized Difference Vegetation Index) showed no significant impact on exercise participation or mental health, the Sky View Factor did. Higher levels of campus openness and exercise frequency were associated with better mental health. The study also underscored that the influence of urban campus landscapes on college students' mental health was mediated by their exercise participation. Notably, spatial openness emerged as the most prominent differentiating factor among urban campus landscape attributes, significantly affecting students' exercise participation and mental health.Originality/valueThus, fostering open campus environments and reducing spatial constraints are vital steps in creating a sustainable urban landscape that can help alleviate potential negative effects on college students' mental health issues.
Dynamic propagation of tensile and shear fractures induced by impact load in rock based on the dual bilinear cohesive zone model
Authors: Wang Yongliang , Zhao Yongcai , Zhang Xin 
Published: August 2024

PurposeThe purpose of this study is to simulate the tensile and shear types of fractures using the mixed fracture criteria considering the energy evolution based on the dual bilinear cohesive zone model and investigate the dynamic propagation of tensile and shear fractures induced by an impact load in rock. The propagation of tension and shear at different scales induced by the impact load is also an important aspect of this study.Design/methodology/approachIn this study, based on the well-developed dual bilinear cohesive zone model and combined finite element-discrete element method, the dynamic propagation of tensile and shear fractures induced by the impact load in rock is investigated. Some key technologies, such as the governing partial differential equations, fracture criteria, numerical discretisation and detection and separation, are introduced to form the global algorithm and procedure. By comparing with the tensile and shear fractures induced by the impact load in rock disc in typical experiments, the effectiveness and reliability of the proposed method are well verified.FindingsThe dynamic propagation of tensile and shear fractures in the laboratory- and engineering-scale rock disc and rock strata are derived. The influence of mesh sensitivity, impact load velocities and load positions are investigated. The larger load velocities may induce larger fracture width and entire failure. When the impact load is applied near the left support constraint boundary, concentrated shear fractures appear around the loading region, as well as induced shear fracture band, which may induce local instability. The proposed method shows good applicability in studying the propagation of tensile and shear fractures under impact loads.Originality/valueThe proposed method can identify fracture propagation via the stress and energy evolution of rock masses under the impact load, which has potential to be extended into the investigation of the mixed fractures and disturbance of in-situ stresses during dynamic strata mining in deep energy development.
The impact of Fintech innovations on digital currency adoption: a blockchain-based study in India
Authors: Bhatnagr Puneett , Rajesh Anupama , Misra Richa 
Published: August 2024

Purpose
The purpose of this study is to integrate customer value theory (CVT) and protection motivation theory (PMT) to understand the factors that have an impact on customer experience, e-trust and intention to recommend, which influence the adoption behaviour of digital currency users.

Design/methodology/approach
A purposive sampling technique was used, and data were gathered through an online survey of 414 respondents. The measurement and structural models were tested using partial least squares structural equation modelling to establish linkages between the constructs.

Findings
Functional, emotional and social values positively impact customer experience. Furthermore, perceived severity, perceived vulnerability, response efficacy and self-efficacy had a positive impact on e-trust. E-trust positively affects customer experience and intention to use the digital currency directly. The study demonstrated that perceived value and protection motivation factors play a significant role in influencing the use of digital currency.

Practical implications
For managers and policymakers interested in the Indian digital currency market, it is suggested that functional utility and emotional and social benefits can enhance user satisfaction. In an e-trust model, user education to increase risk and protection awareness, effectiveness of responses and self-efficacy are critical to building e-trust.

Originality/value
Building on CVT and PMT’s usage in the broader financial services domain, this research empirically confirms the significance of perceived value and protection motivation factors while adopting digital currency. It provides an extensive and multifaceted approach to comprehending customer involvement and trust in digital financial services, thus enhancing the theoretical and empirical knowledge of both the fintech and blockchain industries.