bluuebunny/crossref_metadata_2025_split huggingface dataset:
Predictors of 10‐year smoking abstinence in smokers abstinent for 1 year after treatment
Authors: Álvarez Gutiérrez Francisco Javier , Ferrer Galván Marta , Ruiz Bernal Ana , Medina Gallardo Juan Francisco , Romero Romero Beatriz , Sáez Díaz Antonia , Romero Falcón Auxiliadora 
Published: October 2015

AbstractAimsTo identify factors predicting long‐term relapse to smoking in people attending smoking treatment services who have maintained at least 1 year abstinence.DesignObservational, prospective study with multiple logistic regression used to model predictors of relapse between 1 and 10 years from cessation using variables measured pre‐cessation.Setting and participantsAmong smokers receiving behavioural support for cessation in a clinic in Spain, in some cases with nicotine patches or bupropion, 366 had remained abstinent after 1 year of follow‐up and were included into the study.MeasurementsPredictive measures (disease history, psychological disorder, age of starting smoking, years of smoking, cigarette dependence and smoking cessation treatment used) were obtained at the time of the quit attempt, and ‘failure’ (defined as reported smoking, loss to follow‐up, died or an expired air carbon monoxide reading of > 5 parts per million) was assessed 10 years later.FindingsAt follow‐up, abstinence status was confirmed in 50.5% (n = 185) of participants, while 21.0% (n = 77) reported that they had resumed smoking, and 28.5% (n = 104) were lost to follow‐up (also counted as having resumed smoking). In the multiple regression model, the main factor that predicted relapse had a psychological disorder (odds ratio = 1.85, 95% confidence interval = 1.13–3.05; P < 0.02).ConclusionsHaving a psychological disorder at the time of stopping smoking is a risk factor for relapse to smoking, even after more than 1 year of abstinence.
Organization of the dorsoventral musculature in the wings of the pteropod mollusc Clione limacina
Authors: Satterlie Richard A. 
Published: October 2015

AbstractThe wings of the pteropod mollusc Clione limacina provide forward propulsive force through flapping movements in which the wings bend throughout their length in both dorsal and ventral directions. The musculature of the wings includes oblique, striated muscle bundles that generate the swimming movements of the wings, longitudinal and transverse (smooth) muscle bundles that collapse the wings and pull them into the body during a wing withdrawal response, and dorsoventral muscles that control the thickness of the wings. All muscles act against a hydrostatic skeleton that forms a central hemocoelic space within the wings. Of these muscle types, all have been thoroughly described and studied except the dorsoventral muscles. The fortuitous discovery that the dorsoventral musculature can be intensely labeled with an antibody against the vertebrate hyperpolarization‐activated cation channel (HCN2) provided the opportunity to describe the organization of the dorsoventral musculature in detail. In addition, electrical recordings and microelectrode dye injections supported the immunohistochemical data, and provided preliminary data on the activity of the muscle fibers. The organization and activity of the dorsoventral musculature suggests it may be involved in regulation of wing stiffness during the change from slow to fast swimming.
MicroRNA expression and its implications for diagnosis and therapy of tongue squamous cell carcinoma
Authors: Yu Xin , Li Zheng 
Published: October 2015

AbstractTongue squamous cell carcinoma (TSCC) is the most common type of oral squamous cell carcinomas and is well known for its high rate of lymph nodal metastasis. Despite the identification of many molecular mechanisms in TSCC, the number of deaths associated with TSCC increased during the past 5 years. MicroRNAs (miRNAs) are a family of small non‐coding RNA molecules, which regulate gene expression by either translational inhibition or mRNA degradation. miRNAs have been proven to be key regulators of various biological and pathological processes including cell proliferation, development and tumourigenesis. Increasing evidence has demonstrated that the deregulated miRNAs are implicated in the diagnosis and treatment of TSCC. In this review, we summarized the expressions and roles of miRNAs in TSCC and comment on the potential roles of miRNAs in diagnosis, prognosis and treatment of this malignancy.
Presence of an intracompartmental septum detected by ultrasound is associated with the failure of ultrasound-guided steroid injection in de Quervain’s syndrome
Authors: De Keating-Hart E. , Touchais S. , Kerjean Y. , Ardouin L. , Le Goff B. 
Published: October 2015

The purpose of this study was to find clinical or ultrasound characteristics that might predict the failure of conservative treatment in de Quervain’s syndrome. A total of 42 ultrasound-guided injections have been performed in 41 patients after clinical and ultrasound examination. Patients were immobilized for 3 weeks with a spica splint cast, and clinically evaluated at 3 and 6 weeks and by phone call at the end of the study. Ultrasound showed a septum between the tendons of the first comportment in 34% of the wrists. At last follow-up (mean 15.6 months after the injection) ten patients (24%) had undergone surgery. When comparing ultrasound and clinical characteristics of the operated and non-operated wrists, we found that patients with a high baseline visual analogue scale, with all positive clinical tests and with a persistent intracompartmental septum, had a significantly higher risk of failure following conservative treatment. Level of evidence: III.
Transverse soft tissue distraction preceding separation of complex syndactylies
Authors: Lohmeyer J. A. , Hülsemann W. , Mann M. , Habenicht R. 
Published: October 2015

Various surgical techniques are described for separation of syndactylies leading to good results. However, the use of standard techniques is limited in complex syndactylies with extensive bony fusion and tight soft tissues. The aim of this study was to assess the outcomes of a two-stage procedure involving progressive soft tissue distraction prior to syndactyly release. Between 1996 and 2012 we treated 168 complex syndactylies with this technique. The main indications were syndactylies in Apert syndrome. The digits were distracted through an external fixator at 0.5 mm/day. Distraction of 15–25 mm was achieved. Soft tissue distraction provided additional skin, a wider nail matrix and more bone in the form of callus. Thus subsequent modelling of the fingertips was improved, especially if they were closely fused. This technique facilitates treatment of complex cases and improves aesthetic outcome. Level of evidence: Therapeutic IV
MicroRNA Circulating in the Early Aftermath of Motor Vehicle Collision Predict Persistent Pain Development and Suggest a Role for microRNA in Sex-Specific Pain Differences
Authors: Linnstaedt Sarah D. , Walker Margaret G. , Parker Joel S. , Yeh Eunice , Sons Robert L. , Zimny Erin , Lewandowski Christopher , Hendry Phyllis L. , Damiron Kathia , Pearson Claire , Velilla Marc-Anthony , O'Neil Brian J. , Jones Jeffrey , Swor Robert , Domeier Robert , Hammond Scott , McLean Samuel A. 
Published: October 2015

Background Molecular mediators influencing the transition from acute to persistent musculoskeletal pain following common stress exposures such as motor vehicle collision (MVC) remain poorly understood. In this exploratory, proof of concept study, we compared circulating microRNA (miRNA) expression profiles in the early aftermath of MVC among individuals who did and did not subsequently develop persistent pain. Blood RNA samples were obtained from African American individuals (n = 53) who presented to the emergency department after MVC and were discharged to home after evaluation. The presence or absence of severe pain in the axial region, the most common and morbid region in which post-MVC pain occurs, was assessed 6 weeks following MVC via standardized questionnaire. miRNA expression was determined using miRNA-sequencing; non-parametric analyses were used to compare miRNA expression levels among individuals with and without persistent pain. Results Thirty-two mature miRNA were differentially expressed (p < 0.05) in those with and without severe axial pain at 6 weeks. miR-135a-5p, a regulator of the serotonin receptor that is known to be stress-responsive, differed most significantly between groups (p = 3 × 10−4). This miRNA, and miR-3613-3p (p = 0.001) survived correction for multiple testing (FDR = 0.15) in this small sample. Interestingly, differentially expressed miRNA were enriched for X chromosome location. In secondary analyses, the eight X chromosome miRNA were (a) more significantly associated with axial pain in women than men, (b) expressed more highly in the peripheral blood of women than men, and (c) predicted in pathway analyses (DIANA miRPath v 2.0) to regulate neuronal and neuroendocrine pathways previously implicated in various pain pathologies. Conclusions These results show that circulating miRNA predict persistent severe axial pain after MVC and suggest that they may be involved in the pathogenesis of post-traumatic musculoskeletal pain. However, further studies are needed to determine if these miRNA play a direct causal role.
Praktik Pengawasan Etika Dewan Perwakilan Rakyat Republik Indonesia
Authors: Habibi Nur 
Published: October 2015

Abstract: The Practice of Ethics Oversight in Indonesian Parliament. Court of Parliament's internal ethics is the realization of public oversight that is regulated in the House of Representatives. The existence of these institutions is necessary because the basic theory of representation associated with community control. If there are complaints, violations of ethics and morals to be held and the proceedings had already agreed in the rules. This is different if the question of law as an object of reporting, because the realm of trial also different. The substance of the articles that entrap offenders vary widely and include violations of administrative rules, orderly duties and obligations. Judicial ethics and morals is formed so that embodiment of the principles of good governance and applicable by legislators as expected the Constitution of the Republic of Indonesia and related legislation. Abstrak: Praktik Pengawasan Etika DPR-RI. Pengadilan etika internal DPRRI merupakan realisasi pengawasan publik yang diatur dalam peraturan DPR-RI. Keberadaan lembaga ini sangat diperlukan karena teori dasar perwakilan terkait dengan kontrol masyarakat. Jika ada pengaduan, pelanggaran etika dan moral akan digelar dan proses pengadilannya pun sudah disepakati dalam peraturan. Hal ini berbeda jika persoalan hukum sebagai obyek pelaporannya, karena ranah pengadilannya juga berbeda. Subtansi pasal-pasal yang menjerat pelanggarnya sangat bervariasi, diantaranya pelanggaran tata tertib administrasi, tertib menjalankan tugas dan kewajiban. Peradilan etika dan moral ini dibentuk agar perwujudan prinsip-prinsip kepemerintahan yang baik dan benar dapat diterapkan oleh legislator sesuai harapan Undang-Undang Dasar Negara Kesatuan Republik Indonesia dan peraturan perundang-undangan yang terkait. DOI: 10.15408/jch.v1i1.1447
Kontroversi Pembentukan Perppu Nomor 1 Tahun 2013 Tentang Mahkamah Konstitusi Dalam Ranah Kegentingan Yang Memaksa
Authors: Rohim Nur 
Published: October 2015

Abstract: The Controversy of Perppu Formation No. 1 in 2013 on the Constitutional Court in The Realm Emergency Force. The Placement of Government Regulation in Lieu of Law in the hierarchy of laws and regulations has the fluctuated time. This is an evident from the history of legislation in Indonesia, which puts Perppu on one side are on equal footing the law. The position change is caused due Perppu materially the same as the Act, and there are not formally Perppu Act but closer to the bill that implemented the Act because like the precarious conditions that force. The controversy also sparked debate later, whether the Court has the right to test Perppu or not, was the Parliament also has the authority to accept or reject the nearest Perppu during the trial. As for Perppu No. 1 of 2013 on the Constitutional Court established by the President to rescue the Court assessed by some not qualified in the realm crunch that forced, and even tended to be unconstitutional. However, some others assess in contrary has Perppu urgency to restore the name of the state agency that became the guardian of the constitution. Abstrak: Kontroversi Pembentukan Perppu No. 1 Tahun 2013 Tentang Mahkamah Konstitusi Dalam Ranah Kegentingan Yang Memaksa. Penempatan Peraturan Pemerintah Pengganti Undang-Undang dalam hierarki peraturan perundangundangan dari masa ke masa bersifat fluktuatif. Terlihat dari sejarah peraturan perundang-undangan yang menempatkan Perppu di satu sisi berada setara dengan undang-undang dan di sisi lain berada di bawah undang-undang. Hal ini disebabkan karena secara materiil Perppu sama dengan undang-undang, dan secara formil Perppu bukanlah undang-undang, tetapi lebih dekat kepada RUU yang dilaksanakan laksana undang-undang karena kondisi genting yang memaksa. Perdebatan yang muncul, apakah MK berhak menguji Perppu atau tidak, sedang DPR juga memiliki kewenangan untuk menerima atau menolak Perppu pada masa sidang terdekat. Begitu pula halnya Perppu No. 1 tahun 2013 tentang MK yang dibentuk oleh Presiden guna penyelamatan MK dinilai oleh tidak memenuhi syarat dalam ranah kegentingan yang memaksa, bahkan cenderung inkonstitusional. Akan tetapi sebagian menilai sebaliknya, Perppu ini memiliki urgensitas guna memulihkan nama lembaga negara yang menjadi pengawal konstitusi ini DOI: 10.15408/jch.v1i1.1454
Perlindungan Hukum Terhadap Tenaga Kerja Indonesia (Tinjauan Terhadap UU Nomor 39 Tahun 2004 Tentang Penempatan dan Perlindungan Tenaga Kerja Indonesia)
Authors: Muin Fatkhul 
Published: October 2015

Abstract: The protection of Indonesian workers who work abroad are part of the State's obligation to fulfill the constitutional rights as citizens. Law No. 39 Year 2004 on the Placement and Protection of Indonesian Workers are an integral part of the system that builds upon the mandate of Article 28 subsection 3D, where every citizen has the right country to get a decent job. This means that the rights that every citizen of the country is the right to work outside the country and the state's obligation to provide protection for Indonesian workers who work abroad. Abstrak: Perlindungan terhadap tenaga kerja Indonesia yang bekerja di luar negeri merupakan bagian dari kewajiban negara untuk memenuhi hak-hak konstitusional sebagai warga negara. Undang-Undang Nomor 39 Tahun 2004 Tentang Penempatan dan Perlindungan Tenaga Kerja Indonesia merupakan bagian integral dari sistem yang dibangun berdasarkan amanat Pasal 28 D ayat 3, dimana setiap warga negera berhak untu mendapatkan pekerjaan yang layak. Artinya bahwa hak yang dimiliki setiap warga negera merupakan hak untuk bekerja di luar negeri dan kewajiban negara untuk memberikan perlindungan terhadap tenaga kerja Indonesia yang bekerja di luar negeri. DOI: 10.15408/jch.v2i1.1838
Scope of State Responsibility Against Terrorism in International Law Perspective; Indonesian Cases
Authors: Soemitro Dian Purwaningrum , Pratama Indra Wahyu 
Published: October 2015

Abstract: Scope of State Responsibility Against Terrorism in International Law Perspective; Indonesian Cases. The emergence of global terrorism cases within more than a decade, marked by the tragedy of 9/11, making the issue of it being a big problem. The State as one of the subjects of International Law, into the spotlight. One of the problems that developed was the extent of the responsibility of the State towards acts of terrorism that occurred in the region of his sovereignty, which caused casualties both its own citizens or foreign nationals. In the case of terrorism that happened in Indonesia, the State's responsibility to the International Conventions implementation are very insufficient and the efforts from the country by creating a system of criminal justice to the criminal offence of terrorism has not been a maximum. There should be an obligation of the internationally imposed on it. The problem is if the terrorism was occurred will be submitted to the International Law are likely to be open to foreigners intervention. This is of course contrary to the principles of International Law. However, in the development of International Law as it has evolved in the Principle of the Responsibility to Protect and that should be accepted by any countries in order to attract the embodiment of the country against the security and Human Rights Abstrak: Lingkup Pertanggungjawaban Negara Terhadap Terorisme dalam Perspektif Hukum Internasional pada Kasus Indonesia. Munculnya kasus terorisme global dalam satu dekade, ditandai dengan tragedi 9/11 yang menjadi masalah besar. Salah satu masalah yang berkembang adalah sejauh mana tanggung jawab negara terhadap aksi terorisme yang terjadi di wilayah kedaulatannya, yang menyebabkan timbulnya korban, baik warga negaranya sendiri atau warga negara asing. Dalam kasus terorisme yang terjadi di Indonesia, pertanggungjawaban negara terlihat dalam pelaksanaan Konvensi Internasional dan upaya menciptakan sistem peradilan pidana bagi pelaku tindak pidana terorisme. Jika permasalahan terorisme diserahkan kepada Hukum Internasional, maka cenderung akan membuka intervensi asing. Hal ini tentu saja bertentangan dengan prinsip-prinsip Hukum Internasional. Namun, dalam perkembangan Hukum Internasional telah berevolusi dalam Prinsip Tanggung Jawab untuk melindungi, selain adanya keharusan setiap negara untuk menjaga keamanan dan Hak Asasi Manusia DOI: 10.15408/jch.v2i1.1841
Perubahan Konstitusi dan Reformasi Ketatanegaraan Indonesiaa
Authors: Tamrin Abu 
Published: October 2015

Abstract: Amendment of the Constitution and constitutional reform in Indonesia. The Constitution can be two meanings, namely: a broad sense and narrow sense. Meaning constitution means forming. Constitutional expert in Constitutional Law contains basic law is written. Act of 1945 is a formal document which is the result of political struggle in the past. In the era of the New Order Act of 1945 "sacred" so that the People's Consultative Assembly of Indonesia in the New Order era did not alter the Constitution of 1945. In the reform era to amend the Act of 1945. There was a change of articles of Law 1945. One only Article 1 (2) the first amendment of the Constitution of 1945. Sovereignty is in the people's hands and performed in accordance with the Constitution. There is a state agency that was formed, one of which the Constitutional Court and no state institutions were removed, the Supreme Advisory Council. With the change of the Constitution of 1945, then there was a constitutional reform in Indonesia Abstrak: Perubahan Konstitusi dan Reformasi Ketatanegaraan Indonesia. Menurut K.C. Wheare kata konstitusi dapat menjadi 2 arti yaitu: arti luas dan arti sempit. Menurut Wirjono Projodikoro arti konstitusi berarti membentuk. Baik konstitusi maupun Undang-undang Dasar menurut Pakar Hukum Tata Negara berisi Hukum dasar tertulis. Konstitusi/Undang-undang Dasar 1945 merupakan dokumen formal yang merupakan hasil perjuangan politik bangsa di waktu lampau. Di era orde baru Undang-undang Dasar 1945 “disakralkan” sehingga Majelis Permusyawaratan Rakyat RI di era orde baru tidak mengubah Undangundang Dasar 1945. Di era reformasi dilakukan perubahan Undang-undang Dasar 1945. Ada perubahan pasal Undang-undang Dasar 1945. Salah satunya Pasal 1 ayat (2) perubahan pertama Undang-undang Dasar 1945.Kedaulatan ada di tangan rakyat dan dilakukan menurut Undang-undang Dasar. Ada lembaga negara yang dibentuk, salah satunya Mahkamah Konstitusi RI dan ada lembaga tinggi negara yang dihapus, yaitu Dewan Pertimbangan Agung RI.Dengan adanya perubahan Undang-Undang Dasar 1945, maka terjadi reformasi ketatanegaraan Indonesia. DOI: 10.15408/jch.v2i1.1843
Tindak Pidana Korupsi (Dugaan Penyalahgunaan Wewenang) Pejabat Publik (Perspektif Undang-Undang Nomor 30 Tahun 2014 Tentang Administrasi Pemerintahan)
Authors: . Fathudin 
Published: October 2015

Abstract: Allegation of abuse of authority that committed by public officials is an object to should be examined with the specialty principle (specialialiteit beginsel), because the deviation from this principle would impact to abuse of authority (detournement de pouvoir). In this context, the allegation of abuse of authority is a domain of administrative law (administrative penal law) so that the authority to examine the presence or absence of the element of abuse of authority is absolute competence of administrative court. The application of this mechanism in line with the principle of ultimum remidiun in the application of criminal law. The application of a criminal sanction must be applied as a final sanction after the civil or administrative sanctions. In order to give opportunity for the public to give correction, corrections (No Criminal Penalty before adminsitrative Correction is implemented). Government Administration Act is a response to the polemic of the object of dispute the allegation of abuse of authority that always be drawn directly into the realm of criminal law. Keyword : abuse of authority, administrative law, administrative court Abstrak: Dugaan terjadinya penyalahgunaan wewenang yang dilakukan oleh pejabat pemerintahan merupakan objek yang harus diuji dengan asas spesialitas (specialialiteit beginsel), karena penyimpangan terhadap asas ini akan melahirkan penyalahgunaan wewenang (detournement de pouvoir). Pada konteks ini, maka dugaan penyalahgunaan wewenang merupakan domain hukum administrasi (administratif penal law ) sehingga wewenang untuk memeriksa ada atau tidak adanya unsur penyalahgunaan wewenang merupakan kompetensi absolut peradilam administrasi (Peradilan Tata Usaha Negara). Penerapan mekanisme ini selaras dengan asas ultimum remidiun dalam penerapan hukum pidana, di mana keberadaan pengaturan sanksi pidana harus diletakkan dan diposisikan sebagai sanksi terakhir setalah sanksi perdata maupun sanksi administratif tidak berdaya sebagai upaya memberikan ruang bagi masyarakat luas akan upaya perbaikan, koreksi, dan upaya lainnya sebelum pemidanaan diberikan (No Criminal Penalty before Adminsitrative Correction is implemented). Undang-Undang Nomor 30 Tahun 2014 tentang Administrasi Pemerintahan merupakan jawaban terhadap polemik seputar objek sengketa dugaan penyalahgunaan wewenang yang selama ini langsung ditarik ke ranah hukum pidana padahal sebuah kebijakan tidaklah dapat dikriminalisasi. DOI: 10.15408/jch.v2i1.1844