bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ovarian function recovery in breast cancer patients receiving adjuvant anastrozole treatment: updated results from the phase 3 DATA trial
Authors: Lammers Senna W. M. , Geurts Sandra M. E. , Hermans Karlijn E. P. E. , van Hellemond Irene E. G. , Swinkels Astrid C. P. , Smorenburg Carolien H. , van der Sangen Maurice J. C. , Kroep Judith R. , Honkoop Aafke H. , van den Berkmortel Franchette W. P. J. , de Roos Wilfred K. , Imholz Alexander L. T. , Vriens Ingeborg J. H. , Tjan-Heijnen Vivianne C. G. ,   on behalf of the Dutch Breast Cancer Research Group (BOOG) for the DATA investigators
Published: June 2024

Abstract
Purpose
Patients with chemotherapy-induced ovarian function failure (CIOFF) may experience ovarian function recovery (OFR). Earlier, we showed that OFR during treatment with anastrozole impacted the prognosis of hormone receptor-positive (HR+) breast cancer (BC) patients with CIOFF. Here, we present the long-term follow-up results.

Methods
Postmenopausal women with HR+ BC who were 45–57 years of age and received chemotherapy were identified from the phase 3 DATA study (NCT00301457) on the extended use of anastrozole. Eligible patients were categorised into two groups: patients with CIOFF and definitely postmenopausal patients. Patients with CIOFF were monitored for OFR. Disease-free survival (DFS), distant recurrence-free survival (DRFS), and overall survival (OS) were compared between patients with OFR and patients without OFR using multivariable Cox regression analyses, including OFR as a time-dependent covariate. BC-specific mortality (BCSM) was compared between groups using the Fine and Gray method.

Results
This study included 656 patients: 395 patients with CIOFF and 261 definitely postmenopausal patients. OFR occurred in 39 (12%) of 329 patients with CIOFF who were monitored for OFR. The median follow-up time was 13.3 years. Patients with OFR experienced a deterioration in DFS (hazard ratio (HR) = 1.54; 95% confidence interval (CI) 0.85–2.81), DRFS (HR = 1.51; 95% CI 0.73–3.11), OS (HR = 1.64; 95% CI 0.75–3.55), and BCSM (subdistribution HR = 1.98; 95% CI 0.84–4.63) when compared with patients without OFR.

Conclusion
In patients with CIOFF, OFR during treatment with anastrozole was associated with a deterioration in BC outcomes. These findings underscore the importance of adequate ovarian function suppression in this subgroup of patients.
Judging Gender: The Sentencing of South African Mothers Who Murder Their Children
Authors: Spies Amanda 
Published: June 2024

AbstractWomen who commit filicide are not only judged for their crime but also for their compliance/deviation from societal expectations of motherhood. Motherhood is interpreted through a specific set of socio-cultural norms with mothers needing to be loving, warm, selfless, and protective at all times. Any deviation from these norms can result in harsher sentencing. This article explores the complexity of maternal filicide and, the extent to which gendered constructions of motherhood are used in the South African criminal justice system to sentence women who murder their children. It examines how the dominant narrative identities of the bad/mad/sad mother influence the sentencing of these women and leads to inconsistent sentencing practice within the South African legal framework. By highlighting the disparities in sentencing and the importance of considering contextual information, it calls for reforms to ensure that sentencing aligns with the circumstances of these women, rather than reinforcing stereotypical perceptions of motherhood. It further highlights the need for reform to protect children from filicide.
Enhancing functional thinking in grade 5–6 students through a dynamic mathematics intervention program
Authors: Pittalis Marios , Sproesser Ute , Demosthenous Eleni , Odysseos Eleni 
Published: June 2024

Abstract
The aim of this study was to develop, implement, and evaluate an intervention program focusing on developing Grade 5 and 6 students’ functional thinking. The innovative aspect lies in addressing simultaneously various aspects of function—input–output, covariation, correspondence, and object— in terms of manipulating tasks that involve functional relationships. The program adopts promising design principles, including an inquiry-based approach, engaging students in embodied dynamic mathematics learning environments, and making connections to real-world situations. A sample of 104 students took part in the program. The results showed a significant improvement in students’ performance related to functional thinking between the pre- and post-tests. Grade 5 students’ mean value improved from 0.29 to 0.58 and Grade 6 students from 0.37 to 0.60, respectively. Analysis indicated that students with varying performance potential in developing functional thinking are likely to be significantly affected by the program. Regression analysis showed that students’ gender as well as mathematics- and functions-related self-concept and interest did not serve as predictive factors of students’ gain score magnitude. Students' progression goes along with a significant shift in strategies used. While the dominant strategies in the pre-test relied on recursive and single variation, in the post-test, students moved to covariational and correspondence approaches. The findings indicate that upper primary school students are capable of grappling abstract facets of functions. This underscores the potential effectiveness of targeted interventions that adopt innovative design principles, particularly in light of the limitations of conventional curricula in adequately preparing students to explore functional relationships across diverse contexts.
The invasion threat of the emerging alien cactus Cylindropuntia pallida (Rosa), F.M. Knuth in South Africa and the potential for control using herbicides
Authors: Mokotjomela Thabiso Michael , Nelufule Takalani , Scott Zimbini , Vukeya Loyd Rodney , Xivuri Travor , Matsokane King , Mweli Nobuhle , Magqabi Felicia Lerato , Jaca Thulisile 
Published: June 2024

AbstractThe emerging alien cactus Cylindropuntia pallida (Rose) F.M. Knuth originates from northern Mexico and introduced into South Africa in 1940s as an ornamental plant. Multiple populations of C. pallida have been detected in various areas of South Africa. C. pallida has effective propagule dispersal and rapid recruitment making it a likely key future invader, and thus, is a target for eradication in South Africa. To eradicate C. pallida populations, a foliar spray (i.e. using a 2% concentration of herbicide with fluroxypyr and triclopyr) has been applied to plants in nine populations, with population sizes ranging between 535 and 2701 plants and populations covering areas of 100 –1000 ha. The aims of the study were to investigate the efficacy of the foliar spray method used to eradicate C. pallida; to investigate the impacts of C. pallida invasions on native vegetation integrity; to apply species distribution models (SDMs) to identify suitable climates for C. pallida in South Africa; and to document the biomes vulnerable to the negative impact of C. pallida in South Africa. Results show that foliar spray killed many C. pallida plants (mean percentage of dead plants ± SE, 83.3 ± 6.4; n = 9; range, 70–96%), with adult plants taking about 2 months to die completely. The efficacy of the herbicide was not affected by plant size or the concentration of the herbicide used. The invaded site had significantly greater vegetation cover which persisted across winter compared to the uninvaded site, but the latter site’s vegetation cover significantly dropped in winter. Also, the invaded site had lower plant species diversity than the uninvaded site and was dominated by species in the Poaceae and Asteraceae plant families. Additionally, a normalised difference vegetation index (NDVI) analysis shows that the uninvaded site has higher vegetation cover and health than the invaded site wherein a notable decline in vegetation health was observed between 2019 and 2022. A large area (> 15 million hectares) was predicted to be suitable for invasion by C. pallida in provinces with arid and warm temperate climates - the fynbos and grassland biomes are the most vulnerable. Because of the observed negative impacts, high environmental compatibility, and high cost of clearing large infestations, we advocate for considering the biocontrol method for effectively managing C. pallida invasion in South Africa.
Migration, Partner Selection, and Fertility in Germany: How Many Children are Born in Mixed Unions?
Authors: Gawron Annegret , Milewski Nadja 
Published: June 2024

Abstract
For the German context, we investigate whether the number of children ever born differs between mixed unions (exogamous unions between natives and migrants or migrant descendants) and endogamous unions (unions among co-ethnics). Our theoretical considerations are derived from assimilation theories, which view exogamous unions as indicators of assimilation processes, and the framework on migrant fertility. The migrant (or descendant) partner in an exogamous union may adapt to the majority group, both partners may adapt to each other, or both partners may constitute a selected group in their fertility preferences. However, due to the higher likelihood of conflicts within the partnership and of separation, exogamy may disrupt family formation processes and depress couples’ fertility. Drawing on data from the GSOEP (1984–2020), we estimate generalized Poisson regressions. The results reveal that the number of children ever born is higher in exogamous unions than in endogamous native couples. This general pattern largely persists across migrant generations and regions of origin, but we identify gender differences. While fertility in exogamous unions of native women/migrant (descendant) men is not statistically different from fertility in native/native couples, unions of migrant (descendant) women/native men have more children, especially when controlling for socio-demographic confounders. Our results demonstrate that in the German context, exogamy does not lead to fertility disruptions, and is not straightforwardly associated with assimilation to the fertility of the majority group. Instead, differences in gendered partner choice patterns and life-course transitions may influence the number of children exogamous couples have.
Creating a space for them through autoethnography
Authors: Green Eric , Rupnow Theodore J. , Bracewell Lorna N. 
Published: June 2024

AbstractResearchers in education have begun to address inclusivity for gender-diverse populations, but the authentic experiences of gender-variant students presented directly by the students themselves are largely unheard in the literature of mathematics education. In this co-authored report, we include the experiences of a genderqueer preservice mathematics teacher over the course of a semester at university through their autoethnography and the reflections of a mathematics teacher educator supervising the research. Through this study, we provide educators a window into some ways that gender-variant students may experience the classroom and academia. One goal of this research is to create a space for the authentic voice of gender-variant individuals in the discussion of gender-inclusive education. We highlight implications for mathematics teacher educators involving gender-variant students’ gender journeys as processes instead of moments of coming out, the interdependent process of building relationships of trust, and the importance of trying and failing and trying again as we seek to be more inclusive educators.
Adolescent Cultural Identity Development in Context: The Dynamic Interplay of the Identity Project With Classroom Cultural Diversity Climate in Italy and Germany
Authors: Schachner Maja K. , Hölscher Sophie , Moscardino Ughetta , Ceccon Chiara , Juang Linda , Pastore Massimiliano 
Published: June 2024

AbstractWhile both the classroom cultural diversity climate and curriculum-based interventions can promote cultural identity development, they have not been studied together. Drawing on theories of ethnic-racial identity development, the current study aimed to understand the dynamic interplay of a curriculum-based intervention (the Identity Project) with the classroom cultural diversity climate (heritage culture and intercultural learning, critical consciousness socialization and equal treatment) on cultural identity exploration and resolution. Our sample included 906 mid-adolescents in Italy (32.36% immigrant descent, Mage (SD) = 15.12 (0.68) years, 51.73% female), and 504 early adolescents in Germany (53.86% immigrant descent, Mage (SD) = 12.82 (0.89) years, 42.37% female). Bayesian multivariate linear models show that the Identity Project and a stronger critical consciousness climate in the classroom before the intervention promoted cultural identity exploration at post-test in both countries. However, effects of the intervention and facets of the diversity climate on subsequent resolution were only observed in Italy. There was some evidence that the intervention could alter the classroom cultural diversity climate in Germany, while the intervention could compensate for a less positive diversity climate in the slightly older sample in Italy. Thus, it seems promising to systematically build in opportunities to engage with students’ diverse heritage cultures and identities when developing new curricula, as well as to train teachers to implement such curricula.
Conspiracy Theories, Racial Liberalism and Fantasies of Freedom
Authors: Gillespie Liam , Ghumkhor Sahar 
Published: June 2024

AbstractThis article provides a reading of the Truckers’ Freedom Convoy, which emerged in response to Covid-19 related public health measures in 2022. It argues the movement invites an interrogation of the affective structures of modern liberal subjectivity. We first map the social and political configurations of the movement, highlighting its links with white supremacist conspiracy theories, such as QAnon and Great Replacement Theory. We argue these conspiracies were used to frame Covid-19 countermeasures as the continuation of a perceived trend toward the deliberate but surreptitious erosion of freedom qua white freedom. To this end, the notion the pandemic was really a ‘plandemic’ is informative. For adherents of this view, Covid-19 and its freedom-inhibiting countermeasures were merely deliberate steps towards an already occurring conspiracy. Referencing psychoanalytic theory, the article examines how racial liberalism structured the racist fantasies that drove the freedom movement’s attempts to safeguard freedom by flaunting Covid-19 restrictions. We argue the movement provided its members with a pathway towards jouissance that allowed fear to be performatively refused in the name of freedom. This, we argue, allowed members to embody their imagined status as exalted subjects of the white nation.
Exponential Stability of Impulsive Stochastic Neutral Neural Networks with Lévy Noise Under Non-Lipschitz Conditions
Authors: Ma Shuo , Li Jiangman , Liu Ruonan , Li Qiang 
Published: June 2024

AbstractIn this paper, the exponential stability issue of stochastic impulsive neutral neural networks driven by Lévy noise is explored. By resorting to the Lyapunov-Krasovskii function that involves neutral time-delay components, the properties of the Lévy process, as well as various inequality approaches, some sufficient exponential stability criteria in non-Lipschitz cases are obtained. Besides, the achieved results depend on the time-delay, noise intensity, and impulse factor. At the end of the paper, two numerical examples with simulations are presented to demonstrate the effectiveness and feasibility of the addressed results
A high-performance, parallel, and hierarchically distributed model for coastal run-up events simulation and forecasting
Authors: Di Luccio Diana , De Vita Ciro Giuseppe , Florio Aniello , Mellone Gennaro , Torres Charles Catherine Alessandra , Benassai Guido , Montella Raffaele 
Published: June 2024

AbstractThe request for quickly available forecasts of intense weather and marine events impacting coastal areas is gradually increasing. High-performance computing (HPC) and artificial intelligence techniques are crucial in this application. Risk mitigation and coastal management must design scientific workflow appropriately and maintain them continuously updated and operational. Climate change accelerating increase trend of the past decades impacted on sea-level rise, together with broader factors such as geostatic effects and subsidence, reducing the effectiveness of coastal defenses. Due to this, the support tools, such as Early Warning Systems, have become increasingly more valuable because they can process data promptly and provide valuable indications for mitigation proposals. We developed the Shoreline Alert Model (SAM), an operational Python tool that produces simulation scenarios, ‘what-if’ assumptions, and coastal flooding forecasts to fill this gap in our study area. SAM aims to provide decision-makers, scientists, and engineers with new tools to help forecast significant weather-marine events and support related management or emergency responses. SAM aims to fill the gap between the wind-driven wave models, which produce simulations and forecasts of waves of significant height, period, and direction in deep or mid-water, and the run-up local models, which exstimulate marine ingression in the event of intense weather phenomena. It employs a parallelization scheme that allows users to run it on heterogeneous parallel architectures. It produced results approximately 24 times faster than the baseline when using shared memory with distributed memory, processing roughly 20,000 coastal cross-shore profiles along the coastline of the Campania region (Italy). Increasing the performance of this model and, at the same time, honoring the need for relatively modest HPC resources will enable the local manager and policymakers to enforce fast and effective responses to intense weather phenomena.
English learners learn from worked example comparison in algebra
Authors: Ke Xiaojuan , Newton Kristie J. 
Published: June 2024

AbstractComparison is an important mechanism for learning in general, and comparing two worked examples has garnered support over the last 15 years as an effective tool for learning algebra in mainstream classrooms. This study was aimed at improving our understanding of how Modified for Language Support-Worked Example Pairs (MLS-WEPs) contribute to effective mathematics learning in an ESOL (English to Speakers of Other Languages) context. It investigated a novel instructional approach to help English Learners (ELs) develop better understanding in mathematical reasoning, problem solving, and literacy skills (listening, reading, writing, and speaking). Findings suggest that MLS-WEPs not only enhanced ELs’ ability to solve algebra problems, but it also improved their written explanation skills and enabled them to transfer such skills to different mathematical concepts. Moreover, when controlling for ELs’ prior knowledge, the effectiveness of the MLS-WEPs intervention for performing and explaining calculations did not vary by their English proficiency.
Increasing the immersivity of 360° videos facilitates learning and memory: implications for theory and practice
Authors: Peney Tom , Skarratt Paul A. 
Published: June 2024

AbstractRecent years have seen an increase in the use of immersive virtual reality (IVR) technology in education and training. Studies examining the efficacy of IVR-based interventions have shown improved performance compared to traditional training programmes; however, little is known about whether such improvements can be detected at the level of individual cognitive abilities. The present study sought to examine the effect of IVR on memory using an incidental learning paradigm. Undergraduate volunteers viewed a three-minute 360° video clip under immersive and non-immersive conditions—respectively, using a Head Mounted Display (HMD) or a 2D flat screen monitor—followed by a surprise recall task. Although both devices supported active exploration of the scene in 360°, recall was significantly improved for learners in the immersive condition. These findings suggest that IVR has a facilitative effect on cognition, and that learners may naturally engage with IVR-delivered content without any special instruction or preparation.
Outcomes and patient perspectives of a novel virtual spinal referral pathway in a non-specialist centre
Authors: Low Lyndon Yerng Hsien , Clesham Kevin , E.Murphy Susan , MacNiocaill Ruari , Timlin Marcus , Cleary May 
Published: June 2024

Abstract
Introduction
In Irish orthopaedic centres without dedicated spinal services, the care of patients is facilitated through tertiary referral centres in Dublin, Cork & Galway. The outpatient waiting list for elective spinal opinion remains lengthy and challenging. Previous practice in University Hospital Waterford (UHW) necessitated an assessment with a local non-spinal orthopaedic specialist following a GP referral, incurring up to a 2-year wait prior to subspecialist spinal referral. These patients subsequently incurred a further wait for an appointment at the tertiary referral centre. A novel virtual spine clinic in collaboration with the Mater Misericordiae University Hospital (MMUH) was developed to fast-track this process.

Aims and methods
A retrospective study was performed to audit efficiency by assessing time to initial consultation and time to virtual consultation, treatment outcomes, and patient satisfaction using an adapted patient-satisfaction questionnaire (PSQ-18) and a semi-structured interview. This study reflected the unique nature of patient experience in this pathway.

Results
The median time from referral to being seen in an in-person rapid access physiotherapist combined orthopaedic clinic was 185 days. The median time from initial consultation to virtual consultation was 36 days. The median time interval from virtual consultation to intervention was 110 days. Twenty percent of patients underwent surgery, 14% were further seen in the MMUH outpatients, 7% managed with the trial of physiotherapy, 7% required no follow-up, and 50% planned for radiologically guided spinal injections.

Discussion and conclusion
This novel pathway is efficient for orthopaedic units without a dedicated spinal service. This can easily be replicated across other orthopaedic centres with minimal cost implications.
The MTSK model as a tool for designing tasks for teacher education
Authors: Climent Nuria , Contreras Luis Carlos , Montes Miguel , Ribeiro Miguel 
Published: June 2024

AbstractThis paper studies the knowledge developed by a group of sixty-two pre-service primary teachers during a training session on the definition of a polygon and the mathematical practice of defining. We explore the knowledge developed by pre-service teachers when they carry out a series of training tasks oriented around the practice of defining with primary pupils, within the theoretical framework of the Mathematics Teachers’ Specialised Knowledge model, and using videos of an authentic lesson as prompt. Data were collected by means of video recordings of the implementation of the training tasks, in conjunction with the pre-service teachers’ own written observations as they watched the recorded lesson. A content analysis was carried out on the collected data using the Mathematics Teachers’ Specialised Knowledge model. The results highlight the way in which knowledge of the mathematical practice of defining is constructed, along with the mathematical objects involved in this practice, and pedagogical aspects of defining with young pupils. They also illustrate how a sequence of tasks oriented around a model of teachers’ knowledge can contribute to the development of this knowledge in initial training programmes, and more especially provide orientation about the training of pre-service teachers in the mathematical practice of defining.