bluuebunny/crossref_metadata_2025_split huggingface dataset:
Risk factors for work‐related stress and subjective hardship in health‐care staff in nursing homes for the elderly: A cross‐sectional study
Authors: Pélissier Carole , Vohito Michel , Fort Emmanuel , Sellier Brigitte , Agard Jean Pierre , Fontana Luc , Charbotel Barbara 
Published: April 2015

Risk factors for work‐related stress and subjective hardship in health‐care staff in nursing homes for the elderly: A cross‐sectional study: Carole Pélissier, et al. Université Lyon 1, UMRESTTE (Joint unit IFSTTAR/UCLB), FranceObjectiveThis study aimed to explore potential risk factors for work‐related stress by, detailing working conditions and subjective hardship according to occupational category in health‐care staff working with elderly patients.MethodsA cross‐sectional descriptive survey was conducted in 105 nursing homes for the elderly in France. Data on nursing home working conditions were collected by occupational physicians. The study population was limited to those in direct contact with the elderly, who were divided into 3 occupational groups defined by qualifications and tasks: housekeepers (HKs), nursing assistants (NAs) and nurses (Ns). Employees answered a questionnaire on their perceived working conditions and vocational training courses. Psychosocial stress was assessed with the Siegrist questionnaire.ResultsThe subjects included 706 HKs, 1,565 NAs and 378 Ns, and the findings showed confusion of tasks and responsibilities in the study population. Verbal abuse by residents was reported by 60.9% of HKs (versus 76.2% of NAs and 76.7% of Ns, p<0.001). Physical attack by residents was more frequently reported by NAs (59.1%) than Ns (52.8%) or HKs (38.0%) (p<0.001). Nearly 10% of employees reported clear effort/reward imbalance (10.4% of NAs, 9.2% of Ns and 7.0% of HKs, p=0.059). Great hardship related to proximity to death was reported by 40.5% of HKs (versus 37.3% of NAs and 22.6% of Ns; p<0.001).ConclusionsTo prevent stress related to insufficient ability, nursing home workers should be encouraged to attend job training courses, which should cover knowledge of the specific care needs of elderly patients and of the authority/responsibility required to do their job.
The Interaction Between β‐3 Adrenergic Receptor and Peroxisome Proliferator‐Activated Receptor Gamma Gene Polymorphism to Periodontal Disease in Community‐Dwelling Elderly Japanese
Authors: Yoshihara Akihiro , Sugita Noriko , Iwasaki Masanori , Wang Yanming , Miyazaki Hideo , Yoshie Hiromasa , Nakamura Kazutoshi 
Published: April 2015

Background: It has been hypothesized that β‐3 adrenergic receptor and peroxisome proliferator‐activated receptor gamma (PPARγ) might have gene–environmental and gene–gene interactions in periodontal disease. The purpose of this study is to elucidate the interaction between β‐3 adrenergic receptor and PPARγ gene polymorphism with periodontal disease.Methods: Three hundred thirty‐two postmenopausal females were enrolled, and their serum high‐sensitivity C‐reactive protein (hsCRP) and hemoglobin A1c (HbA1c) were examined. β‐3 adrenergic receptor and PPARγ genotypes were then determined. An oral examination was performed. The number of remaining teeth was counted, and the probing depth (PD) and clinical attachment level (CAL) were measured. Prevalence‐rate ratios (PRRs) were calculated by multiple Poisson regression analyses to evaluate the relationship among periodontal disease markers, such as the number of sites with CAL 4 to 5 or ≥6 mm or PD 4 to 5 or ≥6 mm, and β‐3 adrenergic receptor polymorphisms, PPARγ polymorphisms, and the interaction term adjusted by age, hsCRP, and HbA1c, after converting the number of remaining teeth (n) to an offset variable.Results: In the participants with body mass index (BMI) ≥25, PRRs of β‐3 adrenergic receptor genotype (Trp/Arg and Arg/Arg) for periodontal disease markers were 0.13 to 0.70 (P <0.0001 to 0.74), those of PPARγ genotype (Pro/Pro) were 0.66 to 3.14 (P = 0.01 to 0.68), and those of the interaction term for the two genotypes were 1.69 to 12.61 (P <0.0001 to 0.33). However, in the participants with BMI <25, a constant tendency was not observed.Conclusion: The results confirmed a positive relationship between the interaction term for β‐3 adrenergic receptor genotype and PPARγ genotype and various periodontal markers in obese elderly females.
Masquelet Technique for Midfoot Reconstruction Following Osteomyelitis in Charcot Diabetic Neuropathy
Authors: Mak May Fong , Stern Richard , Assal Mathieu 
Published: April 2015

Case:
We describe a case of ulcerative midfoot osteomyelitis in a patient with Charcot diabetic neuropathy. After debridement, an extensive osseous defect led to staged reconstruction in an attempt to salvage the foot. We describe the presentation, the treatment, and the technical points of this challenging case.

Conclusion:
We reconstructed the midfoot defect with use of the induced-membrane Masquelet technique, successfully reestablishing a stable, well-aligned, plantigrade, ulcer-free foot.
Phase-Behavior Modeling and Flow Simulation for Low-Temperature CO2 Injection
Authors: Pan Huanquan , Chen Yuguang , Sheffield Jonathan , Chang Yih-Bor , Zhou Dengen 
Published: April 2015

Summary
CO2 injection into an oil reservoir at low temperatures (less than 120 °F) can form three hydrocarbon phases—a vapor phase, an oil-rich liquid, and a CO2-rich liquid phase. Most available reservoir simulators cannot handle three-hydrocarbon-phase flash, and the use of two-phase flash may cause significant numerical instability. The issue has been recognized in the industry for a long time. Studies to include three-hydrocarbon-phase flash in compositional simulations exist in the literature. However, this approach results in substantial increases of model complexity and computational cost; thus, it may not be realistic for practical applications (at least for now). In this work, we propose a new pressure/volume/temperature (PVT) modeling procedure to eliminate the three-hydrocarbon-phase region for reservoir-fluid/CO2 mixtures at low temperatures and to study its implication for flow simulation. In our method, the acentric factors of pseudocomponents are adjusted to eliminate the three-hydrocarbon-phase region, which was not considered in any of the previous studies. Then, the experimental data for reservoir-fluid PVT, CO2 swelling test, and minimum miscibility pressure are also matched by adjusting further binary-interaction coefficients, volume-shift parameters, and critical volumes of the pseudocomponents. The procedure is applicable for cases with relatively small three-phase regions (e.g., some fields in west Texas), and can be applied with any PVT simulation software and conventional two-hydrocarbon-phase simulators. The method is considered for two sector models from oil fields in west Texas, with fine-scale (more than 600,000 gridblocks) and upscaled models. Compared with the standard characterization, in which the three-hydrocarbon phases exist, the new fluid model significantly improves the stability of flow simulation, demonstrating the robustness and efficiency of the new procedure. One can view the method as a practical approximation to field-scale simulations of CO2 injection at low temperatures.
Characterization and Flocculating Properties of a Biopolymer Produced byHalomonassp. Okoh
Authors: Okaiyeto Kunle , Nwodo Uchechukwu U. , Mabinya Leonard V. , Okoh Anthony I. 
Published: April 2015

ABSTRACT: The flocculating efficiency and physiochemical properties of purified bioflocculant produced byHalomonassp. Okoh were investigated. Approximately 1.213 g/L of bioflocculant was recovered after fermentation under predetermined ambient conditions. Jar test experimentation revealed optimum bioflocculant concentration as 0.2 mg/mL with flocculation activity of 66.1%. The thermostable bioflocculant retained high flocculation activity after heat treatment at 100 °C for 30 minutes; flocculation activity of 74% was achieved. Chemical analysis showed that the bioflocculant was composed of sugar (26.5%), protein (2.64%), and uronic acid (13.3%). The Fourier infrared spectroscopy spectrum of the purified bioflocculant revealed the presence of hydroxyl and carboxylic functional groups. Thermogravimetric analyses showed a varied decomposition step, thus, an indication of varied composition. Scanning electron micrograph revealed the amorphous structure of the bioflocculant. These results suggest potential applicability of the bioflocculant produced byHalomonassp. Okoh industrially.
Organizational Competencies and Dynamic Accounting Information System Capability: Impact on AIS Processes and Firm Performance
Authors: Prasad Acklesh , Green Peter 
Published: April 2015

ABSTRACT
Accounting information systems (AIS) capture and process accounting data and provide valuable information for decision makers. However, in a rapidly changing environment, continual management of the AIS is necessary for organizations to optimize performance outcomes. We suggest that building a dynamic AIS capability enables accounting process and organizational performance. Using the dynamic capabilities framework (Teece 2007) we propose that a dynamic AIS capability can be developed through the synergy of three competencies: having (1) a flexible AIS, (2) a complementary business intelligence system, and (3) accounting professionals with IT technical competency. Using survey data, we find evidence of a positive association between a dynamic AIS capability, accounting process performance, and overall firm performance. The results suggest that developing a dynamic AIS resource can add value to an organization. This study provides guidance for organizations looking to leverage the performance outcomes of their AIS environment.
Microstructural evolution in deformed duplex stainless steels
Authors: Ryś Janusz , Zielińska-Lipiec Anna 
Published: April 2015

Abstract
The present research is part of a project concerning texture and microstructure evolution upon deformation and annealing in a series of various duplex stainless steels. This article shows a comparison of deformation behavior in two grades of duplex steels subjected to cold-rolling over a wide range of reductions. Both steels under examination showed clear differences in chemical composition and their preliminary treatment included different processes of hot plastic working. Optical microscopy was used to examine changes in morphology and formation of a ferrite–austenite band-like structure upon cold-rolling. Transmission electron microscopy was applied to analyze microstructural evolution and deformation behavior within the ferrite and austenite bands. Additional research included texture measurements for both component phases. Special attention was paid to the ferrite–austenite co-deformation and the structural effects resulting from strain localization at high rolling reductions.
Altered Sirtuin 7 Expression is Associated with Early Stage Breast Cancer
Authors: Aljada Ahmad , Saleh Ayman M. , Alkathiri Moath , Shamsa Heba Bani , Al-Bawab Ahmad , Nasr Amre 
Published: April 2015

Background To evaluate sirtuin-7 (SirT7) mRNA expression status in breast cancer patients with different metastatic stages and survey SirT7 mRNA expression status in eight different types of cancer. Methods The expression of SirT7 in the commercially available TissueScan qPCR Breast Cancer Disease cDNA arrays containing 16 normal, 23 Stage I, 36 IIA, 22 IIB, 8 IIIA, 23 IIIA, 6 IIIB, 13 IIIC, and 5 IV were evaluated by quantitative real-time polymerase chain reaction (qRT-PCR) assay. Similar analysis was performed in TissueScan qPCR Cancer Survey cDNA array, which includes breast, colon, kidney, liver, lung, ovarian, prostate, and thyroid specimens. Results The mRNA expression levels of SirT7 were significantly higher in breast cancer samples compared to normal breast specimens ( P < 0.001). Stratification of patients into groups according to metastatic stages indicated statistically significantly higher levels of SirT7 mRNA in CS-I, CS-II, and CS-III when compared to normal breast tissue ( P < 0.05). Notably, SirT7 mRNA levels were higher in CS-I, CS-IIA, CS-IIB, and CS-IIIA ( P < 0.05). Additionally, there were significantly lower SirT7 mRNA levels in thyroid carcinoma when compared to their corresponding normal tissue ( P < 0.05). Conclusions Our results indicate an increase in the mRNA expression level of SirT7 in breast cancer, particularly in CS-I, CS-IIA, CS-IIB, and CS-IIIA. The relationship of altered SirT7 with breast cancer progression and patient survival should be prospectively explored in future studies.
Bone Marrow Mesenchymal Stem Cell Transplantation Retards the Natural Senescence of Rat Hearts
Authors: Zhang Mingyu , Liu Di , Li Shuang , Chang Lingling , Zhang Yu , Liu Ruixue , Sun Fei , Duan Wenqi , Du Weijie , Wu Yanping , Zhao Tianyang , Xu Chaoqian , Lu Yanjie 
Published: April 2015

Abstract

Bone marrow mesenchymal stem cells (BMSCs) have been shown to offer a wide variety of cellular functions including the protective effects on damaged hearts. Here we investigated the antiaging properties of BMSCs and the underlying mechanism in a cellular model of cardiomyocyte senescence and a rat model of aging hearts. Neonatal rat ventricular cells (NRVCs) and BMSCs were cocultured in the same dish with a semipermeable membrane to separate the two populations. Monocultured NRVCs displayed the senescence-associated phenotypes, characterized by an increase in the number of β-galactosidase-positive cells and decreases in the degradation and disappearance of cellular organelles in a time-dependent manner. The levels of reactive oxygen species and malondialdehyde were elevated, whereas the activities of antioxidant enzymes superoxide dismutase and glutathione peroxidase were decreased, along with upregulation of p53, p21Cip1/Waf1, and p16INK4a in the aging cardiomyocytes. These deleterious alterations were abrogated in aging NRVCs cocultured with BMSCs. Qualitatively, the same senescent phenotypes were consistently observed in aging rat hearts. Notably, BMSC transplantation significantly prevented these detrimental alterations and improved the impaired cardiac function in the aging rats. In summary, BMSCs possess strong antisenescence action on the aging NRVCs and hearts and can improve cardiac function after transplantation in aging rats. The present study, therefore, provides an alternative approach for the treatment of heart failure in the elderly population.

Significance
This study demonstrates that bone marrow mesenchymal stem cells show antisenescence action on aging neonatal rat ventricular cells and heart and improve cardiac function in aging rats. The results provide a novel strategy for retarding the cardiac aging process in physiology and abnormal conditions or pathology. This study also provides an alternative approach for treatment of heart failure in the elderly population.
Variability in the origins and pathways of Pacific Equatorial Undercurrent water
Authors: Qin Xuerong , Sen Gupta Alex , van Sebille Erik 
Published: April 2015

AbstractThe Pacific Equatorial Undercurrent (EUC) transports water originating from a number of distinct source regions, eastward across the Pacific Ocean. It is responsible for supplying nutrients to the productive eastern Equatorial Pacific Ocean. Of particular importance is the transport of iron by the EUC; the limiting nutrient in that region. Although the mean circulation and sources of EUC water are reasonably well understood, it is unclear how the contribution of water from these sources to the EUC vary on seasonal to interannual timescales. Here a Lagrangian analysis is applied to the eddy‐resolving OFAM3 ocean simulation in order to identity variability in the makeup of the EUC over an 18 year period (1993–2010). While ENSO has an influence on the variability of source transport contributions to the EUC, the signal of increased (decreased) transport of water from the LLWBCs during El Niño (La Niña) periods does not translate to substantial changes in the makeup of the EUC between 165°E and 140°W. It is hypothesized that this is due to the large spread in travel times of water parcels as they travel from the source regions into the EUC. The consequent erosion of transport anomalies generated at the different western boundary source regions associated with ENSO may help explain why previous studies found little relationship between variability in iron fluxes off Papua New Guinea shelves and the chlorophyll response in the eastern tropical Pacific.
Internal tides and associated vertical mixing in the Indonesian Archipelago
Authors: Nagai Taira , Hibiya Toshiyuki 
Published: April 2015

AbstractTidal mixing in the Indonesian Archipelago contributes to regulation of the tropical atmospheric circulation and water‐mass transformation in the Indonesian Throughflow. The present study quantifies the vertical diffusivity in the Indonesian Archipelago by driving a high‐resolution three‐dimensional numerical model and investigates the processes of internal tide generation, propagation, and dissipation. The numerical experiment shows that
internal tides are effectively generated over prominent subsurface ridges. The conversion rate from
barotropic to baroclinic energy over the whole analyzed model domain is estimated to be 85.5 GW. The generated internal tides dissipate 50–100% of their energy in close proximity to the generation sites (“near‐field”), and the remaining baroclinic energy propagates away causing relatively large energy dissipation far from the generation sites (“far‐field”). The local dissipation efficiency q, therefore, has an extremely nonuniform spatial distribution, although it has been assumed to be constant in the existing tidal mixing parameterization for the Indonesian Archipelago. Compared with the model‐predicted values, the existing parameterization yields the same order of vertical diffusivity averaged within the Indonesian Archipelago, but significantly overestimated (or underestimated) vertical diffusivity in the near‐field (or the far‐field). This discrepancy is attributable to the fact that the effects of internal wave propagation are completely omitted in the existing parameterization, suggesting the potential danger of using such parameterized vertical mixing in predicting the distribution of SST as well as water‐mass transformation in the Indonesian Seas.
Linearly Tunable Emission Colors Obtained from a Fluorescent–Phosphorescent Dual‐Emission Compound by Mechanical Stimuli
Authors: Mao Zhu , Yang Zhiyong , Mu Yingxiao , Zhang Yi , Wang Yi‐Fan , Chi Zhenguo , Lo Chang‐Cheng , Liu Siwei , Lien Alan , Xu Jiarui 
Published: April 2015

AbstractOrganic mechanoluminochromic materials are mechano/piezo‐responsive and promising for applications in sensors, displays, and data storage devices. However, their switching range of emission is seriously impeded by only one kind of emission (either a fluorescent or phosphorescent peak) in the spectrum of single organic compounds. This study presents a design strategy for pure organic compounds with excellent room‐temperature fluorescent–phosphorescent dual‐emission (rFPDE) properties, which combines the effective factors of dipenylsulfone group, crystalline state, and heavy atom effect. Following the principle of color mixing, myriad emission colors with a wide range from orange to purple and across white zone in a straight line in the chromaticity diagram of the Commission Internationale de l’Eclairage (CIE) can be obtained by simply mechanical grinding the compound. The unique properties could be concentrated on a pure organic compound through this design strategy, which provides a new efficient channel for the discovery of efficient mechano‐responsive organic materials.
Cross‐β Amyloid Nanohybrids Loaded With Cytochrome C Exhibit Superactivity in Organic Solvents
Authors: Kapil Nidhi , Singh Ashmeet , Das Dibyendu 
Published: April 2015

AbstractThe present study reports the development of a unique class of Cytochrome C (CytC)‐loaded cross‐beta amyloid nanohybrids. The peroxidase activity of the bound CytC increased up to two orders of magnitude in organic solvents compared to the activity of unbound CytC in water. The amyloid sequences used in the study feature the nucleating core 17LVFF21 of the beta amyloid (Aβ), which assembled to form homogenous fibers and nanotubes. The morphology and exposed surface of the amyloid nanohydrids critically modulated the CytC activity. A CytC–Ac‐KLVFFAE‐NH2 hybrid featuring nanofiber morphology showed 308‐fold higher activity than unbound CytC in water, which increased to 450‐fold with the nanotube morphology of CytC–Ac‐KLVFFAL‐NH2. Notably, activity declined substantially when the exposed surface charge was detuned by replacing lysine with histidine, thus underpinning the importance of surface charge. This enzyme–amyloid nanohybrid system could facilitate the technological application of enzymes.
Effects of equal‐channel, multiple‐angular extrusion on the physical and mechanical properties of glassy polymers
Authors: Beloshenko Victor A. , Voznyak Andrei V. , Voznyak Yuri V. 
Published: April 2015

ABSTRACTThrough the examples of polycarbonate and poly(methyl acrylate), the evolution of the structure and properties of glassy polymers processed by equal‐channel multiple‐angular extrusion (ECMAE) were studied. It was demonstrated that ECMAE allowed the substantial improvement of the set of strain–strength characteristics of these materials, regardless of the direction of loading applied. With the use of the data from scanning electron microscopy, differential scanning calorimetry, and dilatometry, we found that the simultaneous growth in the strength, plasticity, and impact resistance was related to the formation of a net of biaxially oriented polymeric chains, the decrease in the free volume, and the reinforcement of intermolecular interaction. © 2015 Wiley Periodicals, Inc. J. Appl. Polym. Sci.2015,132, 42180.
Evolution of the crystalline structure and cyclization with changing tension during the stabilization of polyacrylonitrile fibers
Authors: Liu Chang , Hu Leiyang , Lu Yonggen , Zhao Weizhe 
Published: April 2015

ABSTRACTThe effects of tension on the crystalline structure and cyclization of polyacrylonitrile fibers during stabilization were investigated. The degree of cyclization was measured by Fourier transform infrared spectroscopy and differential scanning calorimetry. The crystalline structure was characterized by wide‐angle X‐ray diffraction. When the fibers were heat‐treated at temperatures between 175 and 218°C, the tension mainly affected the cyclization in the amorphous regions through changes in the spatial distance of the chain segments; this led to a relatively higher cyclization degree under moderate tension. When the temperatures ranged from 226 to 232°C, the reactions extended to the crystalline regions. The chemical bonds became greater in the cross section of the fibers, and this was caused by cyclization structures formed in the former stage. Therefore, the optimum tension was higher than in the prior temperature range. At higher temperatures ranging from 238 to 270°C, a crosslinked structure formed, so the optimum tension increased continually. © 2015 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2015, 132, 42182.