bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association between Paraoxonase 2 Gene Polymorphisms and Noise‐induced Hearing Loss in the Chinese Population
Authors: Li Xiu‐Ting , Li Xin , Hu Fei‐Fei , Shen Huan‐Xi , Cao Jing‐Lian , Zhong Li , Zhang Zheng‐Dong , Zhu Bao‐Li 
Published: January 2013

Association between Paraoxonase 2 Gene Polymorphisms and Noise‐induced Hearing Loss in the Chinese Population: Xiu‐Ting LI, et al. Department of Occupational Medicine and Environmental Health, Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, China—ObjectivesThe aim of the present study was to investigate whether PON2 gene polymorphisms (rs7493, rs12026, rs12704796, rs7785846 and rs7786401) are associated with susceptibility to noise‐induced hearing loss (NIHL) in the Chinese population.MethodsA case‐control study was conducted using 615 cases selected without any restriction in age or sex and 644 controls who were matched with the cases in terms of age, gender and the intensity and duration of exposure to noise. Information on these subjects was gathered by questionnaires that were administered through face‐to‐face interviews by trained interviewers.ResultsWe found that the rs7493 CG + GG genotype (OR=1.36, 95% CI, 1.08−1.72), rs12026 CG + GG genotype (OR=1.34, 95% CI, 1.06−1.70), rs7785846 CT + TT genotype (OR=1.36, 95% CI, 1.07−1.71) and rs7786401 GT + TT genotype (OR=1.33, 95% CI, 1.05−1.68) were risk factors for NIHL.ConclusionsPON2 gene polymorphisms may be associated with susceptibility to NIHL in the Chinese population.
Susceptibility to Upper Respiratory Tract Infection and Touching of the Eyes or Nose: A Cross‐sectional Study of Japanese Workers
Authors: Fukunaka Yasushi , Sawada Susumu S. , Nishiura Chihiro , Noguchi June , Tsukamoto Koji , Otsuji Yutaka , Marui Eiji 
Published: January 2013

Susceptibility to Upper Respiratory Tract Infection and Touching of the Eyes or Nose: A Cross‐sectional Study of Japanese Workers: Yasushi FUKUNAKA, et al. Department of Safety and Health, Tokyo Gas Co., Ltd.—ObjectivesThis study was a cross‐sectional survey of Japanese workers regarding the relationship between touching the eyes or nose and susceptibility to URTI in workers.MethodsThe survey respondents were 4,663 Japanese workers. Subjects were surveyed via a self‐administered questionnaire regarding their susceptibility to URTI and how often they touched their eyes or nose. In addition, subjects were surveyed regarding their preventive behaviors and routine behaviors thought to be associated with URTIs. A multiple logistic regression model was used to assess the relationship between susceptibility to URTI and how often the eyes or nose are touched.ResultsResponses from 3,663 individuals who answered the self‐administered questionnaire were analyzed. There were 1,590 individuals (42.9%) with a “frequent incidence of URTIs”, defined as URTIs more than once a year. In terms of how often the eyes or nose are touched, the odds ratios (95% CI) for a frequent incidence of URTIs among the groups responding “sometimes” and “often” were 1.41 (1.21−1.63) and 1.96 (1.59−2.42) (trend test: p<0.001) compared with the groups responding “never” and “almost never”. Multivariate‐adjusted odds ratios adjusted for confounding factors, i.e., behaviors to prevent URTIs, routine behaviors associated with URTIs, age, sex and BMI, were 1.33 (1.14−1.54) and 1.69 (1.36−2.09) (trend test: p<0.001).ConclusionsThe present cross‐sectional study indicates that susceptibility to URTI and how often the eyes or nose are touched are significantly associated in Japanese workers, independent of preventive behaviors and routine behaviors associated with URTIs.
Evaluation of Allogenic Cellular Bone Graft for Ridge Augmentation: A Case Report
Authors: Sindler Arnold J. , Behmanesh Sara , Reynolds Mark A. 
Published: January 2013

Introduction: The reconstruction of alveolar bone defects is often necessary to support successful implant therapy. Although multiple technologies are available to achieve ridge augmentation, the most widely used approaches combine an acellular graft material with guided bone regeneration. Recent advances in tissue banking make it possible to preserve mesenchymal stem cells and osteoprogenitor cells as part of an allogeneic cellular bone matrix that can further enhance the ability of the graft material to provide optimal results for ridge augmentation.Case Presentation: This case report describes the clinical application and results of an allogenic bone matrix product retaining mesenchymal stem and osteoprogenitor cells for alveolar ridge augmentation before implant rehabilitation. The cellular bone matrix supported a radiographic gain of 4 to 6 mm in horizontal ridge width, permitting the placement of dental implants without secondary augmentation.Conclusion: Cellular bone matrix appears to provide an important clinical alternative to acellular bone replacement grafts, particularly in light of its potential to achieve substantial gains in bone volume.
A Case Report Documenting a Rare Diagnosis of a Plasmablastic Lymphoma Situated Within Gingival Tissue in a Patient on Long‐Term Immunosuppressants for Kidney Transplant
Authors: Darcey James C. , Hall Gillian , Roberts Anthony 
Published: January 2013

Introduction: Plasmablastic lymphoma is a high‐grade life‐threatening immunologic malignancy most often found in patients with human immunodeficiency virus (HIV). It is regarded as a unique AIDS‐related lymphoma that has been described in individuals without HIV. Intraoral presentation in such circumstances is extremely rare.Case Presentation: A patient presented with an innocuous epulis and chronic periodontitis. The patient had a history of renal transplant and long‐term immunosuppression with cyclosporine. The localized area of gingival enlargement, although provisionally diagnosed as gingival disease modified by medication, was excised and subsequently confirmed as an acute plasmablastic lymphoma. Excised tissue was sent off for routine histopathologic examination. Latent membrane proteins were found for Epstein‐Barr virus. Atypical lymphoid tissue with multiple immune markers was indicative of a plasmablastic plasmacytoma, but this diagnosis was modified in light of the history of immunosuppression and positive Epstein‐Barr markers to a post‐transplant plasmablastic lymphoma. The patient was managed with a combination of chemotherapy and radiotherapy. The patient is now posttreatment, and there are no signs of recurrence or metastasis.Conclusions: This is a rare presentation. To our knowledge, there have been <10 oral cases ever reported in individuals without HIV. However, surgeons should recognize the importance of clinical diagnoses being supported with histopathologic examination to ensure that potentially life‐threatening misdiagnoses are not made.
Background‐Independent Quantitative Trait Loci for Drought Tolerance Identified Using Advanced Backcross Introgression Lines in Rice
Authors: Wang Yun , Zang Jinping , Sun Yong , Ali Jahuar , Xu Jianlong , Li Zhikang 
Published: January 2013

ABSTRACTDrought is one of the major abiotic stresses limiting rice (Oryza sativa L.) production. Quantitative trait loci (QTL) for drought tolerance (DT) at the reproductive stage were identified with two sets of advanced backcross introgression lines (ILs) using a common donor Tarom Molaei introgressed separately into two recipients used as female parents, Teqing and IR64. A total of 24 and 22 QTL were identified in the IR64 and Teqing backgrounds, respectively, during the reproductive stage under drought and irrigated conditions for thousand‐grain weight, panicle number per plant, filled grains per panicle, seed fertility, and grain yield per plant. Most of these QTL showed obvious differential expression in response to drought stress. In addition, another 12 QTL were detected by the ratio of trait values under drought stress relative to the normal irrigation condition in the two backgrounds. The Tarom Molaei alleles at 8 of 12 loci with increased trait values could improve tolerance under drought stress. Only three (18.8%) DT QTL (QTgw7, QSf7, and QFgp11) were in common in the two backgrounds, clearly suggesting overwhelming genetic background effects on QTL detection for DT. Eight of the DT QTL identified were found to share the same genomic regions with previously reported DT‐related genes. Introgressing and pyramiding of favorable alleles from Tarom Molaei into Teqing and IR64 backgrounds may facilitate development of superior ILs with greater DT levels.
Periosteal Augmentation of Allograft Bone and its Effect on Implant Fixation - An Experimental Study on 12 Dogs§
Authors: Barckman Jeppe , Baas Jorgen , Sørensen Mette , Bechtold Joan E , Soballe Kjeld 
Published: January 2013

Purpose:
Periosteum provides essential cellular and biological components necessary for fracture healing and bone repair. We hypothesized that augmenting allograft bone by adding fragmented autologous periosteum would improve fixation of grafted implants.

Methods:
In each of twelve dogs, we implanted two unloaded cylindrical (10 mm x 6 mm) titanium implants into the distal femur. The implants were surrounded by a 2.5-mm gap into which morselized allograft bone with or without addition of fragmented autologous periosteum was impacted. After four weeks, the animals were euthanized and the implants were evaluated by histomorphometric analysis and mechanical push-out test.

Results:
Although less new bone was found on the implant surface and increased volume of fibrous tissue was present in the gap around the implant, no difference was found between treatment groups regarding the mechanical parameters. Increased new bone formation was observed in the immediate vicinity of the periosteum fragments within the bone graft.

Conclusion:
The method for periosteal augmentation used in this study did not alter the mechanical fixation although osseointegration was impaired. The observed activity of new bone formation at the boundary of the periosteum fragments may indicate maintained bone stimulating properties of the transplanted cambium layer. Augmenting the bone graft by smaller fragments of periosteum, isolated cambium layer tissue or cultured periosteal cells could be studied in the future.
Life's Two Certainties: An Estate and Gift Tax Consulting Case
Authors: Huston G. Ryan , Huston Janet M. 
Published: January 2013

ABSTRACT:
This case requires students to perform the work of a partner in a private wealth practice, presenting a client with a comprehensive estate and gift tax plan. Employing three separate fictitious clients representing people with varying estate planning needs, the case requires students to consider multiple issues, both tax and non-tax. Estate and gift tax planning is different from income tax planning because of the impact of specific non-tax factors, such as family dynamics and fears and unknowns related to death. To develop a comprehensive estate and gift tax plan for their client, students must incorporate course topics and apply them to their particular fact pattern. This case furthers students' understanding of the interplay between estate and gift tax rules, develops their ability to generate relevant questions, exposes them to client dynamics, and cultivates critical thinking skills in the context of estate and gift tax planning.
The n-Point Condition and Rough CAT(0)
Authors: Buckley Stephen M. , Hanson Bruce 
Published: January 2013

Abstract
We show that for n ≥ 5, a length space (X; d) satisfies
a rough n-point condition if and only if it is rough
CAT(0). As a consequence, we show that the class
of rough CAT(0) spaces is closed under reasonably
general limit processes such as pointed and unpointed
Gromov-Hausdorff limits and ultralimits.
A multi-isotope (δ13C, δ15N, δ2H) approach to connecting European breeding and African wintering populations of barn swallow (Hirundo rustica)
Authors: Hobson Keith A. , Møller Anders P. , Van Wilgenburg Steven L. 
Published: January 2013

A multi-isotope (δ13C, δ15N, δ2H) approach to connecting European breeding and African wintering populations of barn swallow (Hirundo rustica)
Establishing links between breeding and wintering populations of longdistance
migratory birds and other animals is fundamental to several
aspects of migration research. However, severe limitations in our ability
to track small-bodied migratory species still limits this field despite several
recent technological breakthroughs. The measurement of naturally
occurring stable isotopes of several elements in the tissues of migrants that
travel across isotopic gradients or isoscapes has the potential to identify
large scale migratory connectivity without some of the biases associated
with the use of extrinsic markers. We investigated migratory connectivity
between European breeding and African wintering populations of barn
swallow (Hirundo rustica) by comparing feather isotope (δ13C, δ15N, δ2H)
values with those expected from previously established feather isotopic
clusters for Africa. We used a likelihood approach to assigning individuals
to molt origins that also made use of prior information provided by ring
recoveries as part of the EURING and SAFRING ringing efforts. We found
evidence for strong isotopic spatial structure in the dataset, supporting
the notion of a migratory divide in Europe with birds breeding in the
Netherlands, Denmark, Germany and Eastern Europe wintering in southern
Africa and virtually all samples from Switzerland westward being assigned to
clusters in the northern portion of the species’ winter range. Individuals from
the United Kingdom were assigned to areas including Namibia, Botswana,
northern South Africa, and along the coast of Mozambique and Tanzania.
Birds wintering in the northernmost region of the wintering grounds tended
to breed in the southernmost region of the breeding grounds, providing
some evidence of leap-frog migration. We detected a strong latitudinal
threshold in feather δ13C in Europe for African-grown feathers, suggesting
that birds breeding in southern Europe (< 50° Latitude) primarily used
C3-dominated habitats in Africa, whereas birds in northern Europe (> 53°
Latitude) primarily used C4-dominated habitats. Our results emphasize
the power in using a multi-isotope approach to assign individuals and
populations to known continental-scale isoscapes and the advantages of
combining isotopic and conventional (ring recovery) information within a
Bayesian assignment framework.
Strong Migratory Connectivity in a Declining Arctic Passerine
Authors: Macdonald C.A. , Fraser K.C. , Gilchrist H.G. , Kyser T.K. , Fox J.W. , Love O.P. 
Published: January 2013

Abstract
Determining how animal populations are linked in space and time is
important for identifying factors influencing population dynamics and
for effective conservation and management. Arctic-breeding migratory
passerines are declining and at risk due to forecasted climate change, but
are a challenge to monitor due to their inaccessible breeding locations,
long-distance migration routes and small body size. For the first time, we
combine sub-gram geolocator technology and stable-isotope analysis with
mark-recapture (banding) and citizen science data to determine patterns
of migratory connectivity for multiple populations of a declining North
American Arctic-breeding passerine, snow bunting (Plectrophenax nivalis).
We show strong evidence for an east-west parallel migratory system, with
Hudson Bay acting as a migratory divide. While band recoveries suggest
strong migratory connectivity among eastern wintering populations
(more than 95% of band recoveries reveal connections between western
Greenland and eastern North America), novel application of geolocators
and stable-hydrogen isotope analysis to a Canadian breeding population
revealed a high degree of migratory connectivity within western North
American wintering populations. Our results also show distinct differences
in migratory distance between eastern and western populations, and
illustrate how applying multiple techniques can effectively be used to track
migration patterns of remote populations. Differences in annual distribution
and migratory distance suggest that separate consideration of eastern
and western wintering populations may improve future conservation and
management efforts for this species.
Structural investigations of CXCR2 receptor antagonists by CoMFA, CoMSIA and flexible docking studies
Authors: Gunda Shravan Kumar , Anugolu Rohith Kumar , Tata Sri Ramya , Mahmood Saikh 
Published: January 2013

=
Three-dimensional quantitative structure activity relationship (3D QSAR) analysis was carried out on a et of 56 N,N’-diarylsquaramides, N,N’-diarylureas and diaminocyclobutenediones in order to understand their antagonistic activities against CXCR2. The studies included comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA). Models with good predictive abilities were generated with CoMFA q2 0.709, r2 (non-cross-validated square of correlation coefficient) = 0.951, F value = 139.903, r2 bs = 0.978 with five components, standard error of estimate = 0.144 and the CoMSIA q2 = 0.592, r2 = 0.955, F value = 122.399, r2 bs = 0.973 with six components, standard error of estimate = 0.141. In addition, a homology model of CXCR2 was used for docking based alignment of the compounds. The most active compound then served as a template for alignment of the remaining structures. Further, mapping of contours onto the active site validated each other in terms of residues involved with reference to the respective contours. This integrated molecular docking based alignment followed by 3D QSAR studies provided a further insight to support the structure-based design of CXCR2 antagonistic agents with improved activity profiles. Furthermore, in silico screening was adapted to the QSAR model in order to predict the structures of new, potentially active compounds.
Heterocyclic compounds based on 3-(4-bromophenyl) azo-5-phenyl-2(3H)-furanone: Anti-avian influenza virus (H5N1) activity / Heterociklički derivati 3-(4-bromfenil) azo-5-fenil-2(3H)-furanona: Djelovanje na virus ptičje gripe (H5N1)
Authors: Flefel Eman M. , Abdel-Mageid Randa E. , Tantawy Waled A. , Ali Mohamed A. , Amr Abd El-Galil E. 
Published: January 2013

1
3-[2-(4-Bromphenyl)hydrazono]-5-phenyl-furan-2(3H)-one () was used for preparation of some novel pyrazole, pyridazinone, oxadiazole, triazole, thiazolidine and thioxopyrimidine derivatives. Some of the prepared products were tested for anti-avian influenza virus activity and revealed promising antiviral activity against H5N1 virus [A/Chicken/Egypt/1/20 % (H5N1)] by determination of both EC50 and LD50 and confirmed by plaque reduction assay on Madin-Darby canine kidney cells. Compounds 3-[2-(4-bromophenyl)hydrazono]-5-phenylfuran-2(3H)-one (1), 1-(4-bromophenyl)-N-hydroxy-5-phenyl-1H-pyrazole-3-carboxamide (5) and 1-(4-bromophenyl)-N-{2,3-dihydro-4-hydroxy-3-phenyl-6-oxo-2-thioxopyrimidin-1(6H)-yl}-5-phenyl-1H-pyrazole-3-carboxamide (12a) showed the highest effects. Detailed synthesis, spectroscopic data, and antiviral activity of the synthesized compounds are reported.
The effect of some herbal extracts and pesticides on the biological parameters of Bemisia Tabaci (genn.) (hem.: Aleyrodidae) pertaining to tomato grown under controlled conditions
Authors: Jafarbeigi Fatemeh , Samih Mohammad Amin , Zarabi Mehdi , Esmaeily Saeideh 
Published: January 2013

Abstract
The sweet potato whitefly, Bemisia tabaci (Genn.) (Biotype A: Hem.: Aleyrodidae) is one of the most important pests in Iran. The development of alternative methods that are not chemical applications, is necessary in pest management for the sake of human health and for the safety of the environment. In this research project, the effect of four herbal compounds Fumaria parviflora Lam. (Fumariaceae), Teucrium polium L. (Lamiaceae), Calotropis procera (Willd.) R. Br. (Asclepiadaceae), Thymus vulgaris L. (Lamiaceae) on the same biological parameters of cotton whitefly were compared with the insecticides azadirachtin and pymetrozin. The results showed significant differences between herbal compounds and insecticides on: egg longevity (F6, 39 = 2.96, p < 0.05), pupa longevity (F6, 37 = 4.49, p < 0.01) and adult longevity (F6, 31 = 4.47, p < 0.01); egg mortality (F6, 39 = 6.71, p < 0.001), total egg mortality (F6, 39 = 6.71, p < 0.001), sex ratio (female) (F6, 30 = 3.49, p < 0.01), oviposition period (F6,31 = 7.50, p < 0.001) and total fecundity/female (F6, 31 = 8.23, p < 0.001). These results indicated that a fumitory extract and pymetrozin had the best effect on longevity and mortality, respectively. According to the results, the fumitory had a noticeable effect on the different life stages of the sweet potato whitefly.
Effects of farming system, chemical control, fertilizer and sowing density on sharp eyespot and Rhizoctonia spp. in winter wheat
Authors: Lemańczyk Grzegorz 
Published: January 2013

Abstract
Effects of agronomic practices on the occurrence of sharp eyespot and Rhizoctonia spp. in winter wheat were determined in two field experiments. In Experiment 1, in the village of Osiny, a comparison was made of disease in different farming systems. The farming systems were: organic, integrated, conventional, and monoculture. In Experiment 2, in the village of Mochełek, the effects of different chemical controls (no treatment, herbicide, herbicide + fungicide), mineral fertilizer doses (147 and 221 kg/ha NPK) and sowing densities (400 and 600 grains/m2) on the occurrence of sharp eyespot were compared in wheat grown in short-term monoculture. There was considerably more sharp eyespot in 2007 (disease index 1.63-29.5%) than in other years. Significant effects of the treatments were mostly noted at the milk ripe growth stage. The fewest sharp eyespot symptoms were seen in the integrated farming system. The most sharp eyespot symptoms were seen in the conventional and organic systems. There was a tendency for an increased intensity of symptoms in successive wheat-growing years of short-term monoculture. The application of pesticides showed no clear effect on the occurrence of sharp eyespot. The herbicide resulted in increased or decreased disease intensity depending on the cultivation year and the date of observation. Fungicide application did not decrease infection. Without chemical control, more symptoms were observed at the lower NPK rate. There were more symptoms at the higher sowing density. Stems with sharp eyespot symptoms were mostly infected by Rhizoctonia cerealis, and less frequently by R. solani. Binucleate Rhizoctonia spp., which could not be identified to species using polymerase chain reaction (PCR) techniques, were also recorded. Two R. zeae isolates were also obtained from stems with disease symptoms in Mochełek. R. solani was more often isolated from roots or stems with symptoms of true eyespot or fusarium foot rot. Most isolates of Rhizoctonia spp. were obtained at the milk ripe stage. A wheat-growing system and chemical control did not greatly affect the frequency of Rhizoctonia spp.