bluuebunny/crossref_metadata_2025_split huggingface dataset:
ALPHA LABELINGS OF DISJOINT UNION OF HAIRY CYCLES
Authors: Rajasekaran G. , Uma L. 
Published: July 2024

In this paper, we prove the following results: 1) the disjoint union of \(n\geq 2\) isomorphic copies of the graph which is obtained by adding a pendent edge to each vertices of the cycle of order 4 admits \(\alpha\)-valuation; 2) the disjoint union of two isomorphic copies of the graph which is obtained by adding \(n\geq 1\) pendent edge to each vertices of the cycle of order 4 is admits \(\alpha\)-valuation; 3) the disjoint union of two isomorphic copies of the graph obtained by adding a pendent edge to each vertex of the cycle of order \(4m\) admits \(\alpha\)-valuation; 4) the disjoint union of two non-isomorphic copies of the graph obtained by adding a pendent edge to each vertices of the cycle of order \(4m\) and \(4m-2\) admits \(\alpha\)-valuation; 5) the disjoint union of two isomorphic copies of the graph which is obtained by adding a pendant edge to each vertex of the cycle of order \(4m-1(4m+2)\) is admitted graceful (\(\alpha\)-valuation).
The Influence of Viral Marketing and Influencer Marketing Against Purchase Intention TikTok Account @Somethincofficial
Authors: Br lumban gaol Fransiska Perintis 
Published: July 2024

The purpose of this study is to ascertain how viral marketing and influencer marketing on TikTok influence consumers' intent to purchase Somethinc items. Data for this study were gathered quantitatively utilizing survey methods. A survey distributed via Google Form served as the research tool. In this study, 414 respondents who followed @somethincofficial on TikTok served as samples. Multiple linear analysis and descriptive analysis are the analysis methods employed. The findings of this study indicate that influencer marketing has an impact on purchase intention on TikTok accounts @somethincofficial whereas viral marketing has an impact on those accounts. Influencer marketing and viral marketing both influence future purchases. Based on the findings of the ability of independent variables to determine the coefficient of determination (viral marketing), The independent variable (and influencer marketing) in this study affects the dependent variable by 54%, while other variables in the study account for the remaining 46% (1 - 0.540).
Análisis del tiempo de evaluación y aprobación de protocolos de investigación sometidos a los Comités en materia de Investigación del Instituto Nacional de Pediatría
Authors: Nava Herrera Alberto Arturo , Medina Vera Isabel , Oria Hernández Jesús Antonio , Gónzalez Zamora José Francisco 
Published: July 2024

OBJETIVO: Analizar los tiempos asociados al proceso de evaluación y aprobación de protocolos de investigación sometidos a los Comités en materia de investigación para la salud del Instituto Nacional de Pediatría
MATERIALES Y MÉTODOS: Estudio comparativo, longitudinal, observacional, retrospectivo donde se analizó la información de los protocolos sometidos para su evaluación en el periodo de enero a diciembre de 2022. Se recolectó la siguiente información: títulos de los protocolos, fechas de recepción por comités, fechas de evaluación, tipos de dictámenes, fechas de envío de dictamen y fechas de respuesta del investigador.
RESULTADOS: Se evaluaron 88 protocolos de los cuales 67 (76.1%) fueron aprobados; de estos, la mayoría se aprobaron en su segunda o tercera revisión (55.2% y 34.3% respectivamente, total 89.5%). La mediana de días entre el sometimiento y aprobación de un protocolo de investigación fue de 47 días (RI: 30-87), con tiempos similares entre el utilizado para emitir un dictamen por los comités y el tiempo que los investigadores utilizaron para solventaros sus observaciones (21 días RI: 16-32 vs 25 días RI: 8-56; p=0.395), sin observarse diferencias estadísticamente significativas.
CONCLUSIONES: El tiempo de aprobación de un protocolo de investigación en la institución analizada, fue una responsabilidad compartida entre los comités y el investigador principal. Consideración importante al establecer programas de apoyo institucional para investigación.
Przegląd metod immobilizacji, waloryzacji oraz kierunków zagospodarowania popiołów
Authors: Żak Grażyna ,   Instytut Nafty i Gazu – Państwowy Instytut Badawczy, Wojtasik Michał ,   Instytut Nafty i Gazu – Państwowy Instytut Badawczy
Published: July 2024

Pomimo istnienia wielu nowoczesnych i niskoemisyjnych metod wytwarzania energii spalanie paliw stałych nadal stanowi istotny element w miksie energetycznym wielu krajów, w tym w Polsce. Nie przewiduje się, aby w ciągu najbliższych lat sytuacja ta uległa drastycznej zmianie, szczególnie że na znaczeniu przybiera spalanie paliw biomasowych pochodzenia rolniczego, biomasy leśnej oraz odpadów komunalnych czy osadów ściekowych. W efekcie spalania paliw stałych powstają różnego rodzaju emisje, w tym znaczny wolumen w postaci popiołów. Szczególną pozycją są popioły powstające w procesie termicznego przetwarzania odpadów komunalnych. Jest to produkt, którego zagospodarowanie cechuje się znaczną złożonością. Fakt ten wynika przede wszystkim z wysokich zawartości metali ciężkich. Z tego względu popioły te przed składowaniem są immobilizowane, czyli poddawane procesowi polegającemu na zapobieganiu uwalniania z nich szkodliwych substancji. W artykule przedstawiono przegląd literaturowy dotyczący różnych metod przetwarzania popiołów, dzięki którym możliwe jest ich dalsze składowanie lub wykorzystanie. Opisano procesy immobilizacji, czyli zabezpieczenia niebezpiecznych popiołów w celu ograniczania uwalniania z nich metali ciężkich. Dzięki tym zabiegom popioły ze spalania odpadów komunalnych nie stanowią tak dużego zagrożenia jak popioły nieprzetworzone. Przedstawiono również przegląd metod waloryzacji popiołów, czyli ich utylizacji poprzez uzyskanie na ich bazie innych materiałów gotowych do wykorzystania w różnych obszarach gospodarki. Jak się okazuje, popioły ze spalania odpadów komunalnych mogą być składnikiem geopolimerów oraz zeolitów – nowoczesnych materiałów o wielkim potencjale wykorzystania, np. w budownictwie. Podejście takie, czyli przetworzenie odpadów w kierunku pełnowartościowych materiałów, jest zgodne z zasadami gospodarki o obiegu zamkniętym.
Investigation of the effect of the combined methods on the rheological properties of high-paraffin oils
Authors: Gurbanov Guseyn R. ,   Azerbaijan State Oil and Industry University, Gasimzade Aysel V. , Abbasova Leili A. ,   Azerbaijan State Oil and Industry University,   Azerbaijan State Oil and Industry University
Published: July 2024

The impact of a magnetic field, the Difron-4201 depressor additive, a new composition with the conventional name N-1, and the synergistic effect of N-1 combined with a magnetic field on paraffin deposition and freezing temperature in high paraffin crude oil was studied for the first time. Laboratory experiments were conducted using the “cold finger” method at surface temperatures of 5, 10, 15, 20, and 25°C to assess paraffin deposition. The combined method (N-1 + magnetic field) demonstrated the most significant reduction in paraffin deposition across varying temperatures. The physical, chemical, and physicochemical effects on the freezing temperatures of high paraffin oil were evaluated following the RD standard method. Optimal usage rates were determined to be 600 g/t for the Difron-4201 depressor additive and 500 g/t for the N-1 composition. Similar to paraffin precipitation, the combined influence of the magnetic field and N-1 composition showed the most effective reduction in freezing temperature. It was also determined that the magnetic field, the Difron-4201 depressor additive, the new composition N-1, and the combined N-1 + magnetic field method affect the effective viscosity of high paraffin crude oil, with the combined method producing the most notable changes. Additionally, the bactericidal properties of the new composition N-1 were evaluated by studying its effect on sulfate-reducing bacteria over fifteen days under laboratory conditions using Postgate-B nutrient medium. N-1 exhibited the highest bactericidal effect at a concentration of 500 g/t, achieving a bactericidal effectiveness of 97%.
Efficacy and safety of drug-coated balloon-only technique versus provisional T-stenting with drug-eluting stent in true coronary bifurcation lesions: study protocol for a multi-center, randomized, controlled, noninferiority trial
Authors: Wang Wenyao , Qi Jiating , Wang Jingjia , Meng Xiangbin , Gao Jun , Zhang Kuo , Chen Jing , Shao Chunli , Tang Yi-Da 
Published: July 2024

Abstract

Background: Provisional T-stenting is generally acknowledged for treating coronary bifurcation lesions, but risk of adverse cardiac events is still high. Drug-coated balloon (DCB) has been proved non-inferior and even superior to stent combined with general balloon strategy but the efficacy and safety of using it alone in bifurcation lesions needs further investigation. Hence, this prospective, multi-center, randomized, controlled study was devised to test whether DCB-only technique is non-inferior to provisional T-stenting with drug-eluting stent (DES) for true coronary bifurcation lesions.
Methods: A total of 1000 patients with true coronary bifurcation lesions (Medina classes 1.1.1, 1.0.1 or 0.1.1) from 20 research institutes in China who meet the inclusion criteria and satisfy no exclusion criteria will be enrolled in this trial. Subjects will be randomly assigned to the RESTORER DCB group or the DES group in a 1:1 ratio. Patients in the DCB group will receive DCB treatment only, while those in the DES group will undergo provisional T-stenting. Coronary angiography will be performed by well-trained operators and participants will take antiplatelet or anticoagulation medication in accordance with the protocol. The first primary endpoint is the target lesion failure (TLF) rate at 12 months postoperatively. The second primary endpoint is clinical net event rates at 12 months postoperatively. The follow-up data will be collected at 1, 6 and 12months and 2 and 3 years postoperatively by phone call or clinic visit. Statistical analysis will test the noninferiority of DCB regarding the first primary endpoint and further test the superiority of DCB concerning the second primary endpoint if the noninferiority is supported.
Discussion: This trial is intended to test whether DCB-only technique is non-inferior to provisional T-stenting with DES in true coronary bifurcation lesions, which will provide evidence for strategy selection in treating such patients.
Trial registration: NCT04842838 [ClinicalTrials.gov] [registered on April 13, 2021]
Accurate single domain scaffolding of three non-overlapping protein epitopes using deep learning
Authors: Correia Bruno , Castro Karla , Watson Joseph , Wang Jue , Southern Joshua , Ayardulabi Reyhaneh , Georgeon Sandrine , Rosset Stéphane , Baker David 
Published: July 2024

Abstract

De novo protein design has seen major success in scaffolding single functional motifs, however, in nature most proteins present multiple functional sites. Here we describe an approach to simultaneously scaffold multiple functional sites in a single domain protein using deep learning. We designed small single domain immunogens, under 130 residues, that simultaneously present three distinct and irregular motifs from respiratory syncytial virus. These motifs together comprise nearly half of the designed proteins, and hence the overall folds are quite unusual with little global similarity to proteins in the PDB. Despite this, X-ray crystal structures confirm the accuracy of presentation of each of the motifs, and the multi-epitope design yields improved cross-reactive titers and neutralizing response compared to a single-epitope immunogen. The successful presentation of three distinct binding surfaces in a small single domain protein highlights the power of generative deep learning methods to solve complex protein design problems.
Screening for cognitive impairment in routine clinical oncology practice: a pilot study using Patient Reported Outcome Measures and online cognitive testing in melanoma and breast cancer patients
Authors: Albers E. A.C. , de Ligt K. M. , Ploeg I. M.C van der , Wouters M. J.W.M. , Schagen S. B. , de Poll-Franse L.V. van 
Published: July 2024

Abstract

Purpose
This pilot study aimed to identify patients with cognitive impairment by a stepped-care use of Patient Reported Outcome Measures (PROMs) and online cognitive tests implemented in routine clinical practice.
Methods
Self-reported cognitive functioning was measured in breast cancer or melanoma patients, six months after start of treatment, with two items of the EORTC QLQ-C30. Scores below a predefined threshold of 75 indicated clinically relevant cognitive impairment. Subsequent objective cognitive functioning was assessed with an online test battery, consisting of 7 tests that measure learning and memory, attention and working memory, information processing, executive functioning, and psychomotor speed. Impaired cognitive functioning was defined as a z-score of ≤ − 1.5 on 2 or more tests, a z-score of ≤ − 2 on one single test, or both.
Results
In total, 261 patients completed PROMs six months after start treatment; 38/154 (25%) melanoma and 43/107 (40%) breast cancer patients reported clinically relevant cognitive impairment. Of them, 12/38 (32%) melanoma and 15/43 (35%) breast cancer patients opted for online cognitive testing. Of those completing formal tests, cognitive impairment was identified in 4/12 (33%) melanoma and 10/15 (67%) breast cancer patients.
Conclusion
A significant number of patients report cognitive problems six months after starting treamtment. Only 32–35% was able and/or expressed the need for further diagnostics. Among those who are formally tested, 33–67% had cognitive impairment, which is 3–9% of the total group that completed PROMs in routine care.
Implications for Cancer Survivors:
This pilot study suggests that a stepped care pathway for cognitive problems is relevant and also mangable in terms of clinical care.
Is early use of SGLT2i necessary even in patients with cardiovascular risk factors? : A prospective study regarding the effect of SGLT2i on left ventricular diastolic function
Authors: Jeon Kina , Jang Shin Yi , Lee You-Bin , Kim Jihoon , Chang Sung-A , Park Sung-Ji , Lee Sang-Chol , Park Seung Woo , Lee Moon-Kyu , Kim Eun Kyoung , Hur Kyu Yeon 
Published: July 2024

Abstract

Background
There are insufficient studies to determine whether sodium glucose cotransporter type 2 inhibitors (SGLT2i) will help reduce early diabetic cardiomyopathy, especially in patients without documented cardiovascular disease.
Method
We performed a single center, prospective observation study. A total of 90 patients with type 2 diabetes (T2DM) patients without established heart failure or atherosclerotic cardiovascular disease were enrolled. Echocardiography, cardiac enzyme, and glucose-control data were examined before and 3 months after the administration of SGLT2i (dapagliflozin 10mg per day). Cardiovascular risk factors included hypertension, smoking, obesity, dyslipidemia, and old age. The primary end point was the change of E/e’ before and after administration of SGLT2i.
Results
Most patients (86.7%) had 3 or more cardiovascular risk factors, and about 32% had all 5 risk factors. Although the decrease in E/e’ after the administration of SGLT2i was observed in 20% of enrolled patients, there was no significant difference in average E/e’ value or left atrial volume index before and after the SGLT2i medication. Even in patients with all known risk factors including old age, E/e’ value did not decrease after adding SGLT2i (8.9 ± 2.4 vs. 8.7 ± 3.2). There was a statistically significant difference in E/e’ change after the SGLT2i administration between patients younger than 60 years and those older than 60 years (-0.7 ± 2.2 vs. 1.1 ± 2.8, p = 0.002).
Conclusion
In T2DM patients without documented cardiovascular disease including heart failure, administration of SGLT2i showed no improvement in diastolic function profile. Further large-scale randomized studies are needed to determine who will benefit from potential cardiovascular events with early addition of SGLT2i.
Unleashing employees’ entrepreneurial potential in Saudi start-up companies: The role of psychological empowerment as a mediator between entrepreneurial leadership and employees’ entrepreneurial behavior
Authors: Abanumay Razan , Alalwani Eman , Dukhaykh Suad 
Published: July 2024

Abstract

The business market through which start-ups operate has become intensively competitive in recent years. Developing employees’ entrepreneurial behavior is thus a priority for thriving in such conditions. This research attempts to explore the antecedent of such behavior by testing a research model that incorporates the linkages between entrepreneurial leadership, psychological empowerment, and employees' entrepreneurial behavior. The SEM analysis performed on a sample of 256 employees working in Saudi start-up companies showed that entrepreneurial leadership has no direct effect on employees’ entrepreneurial behavior; instead, the impact turned out to be indirect through enhancing employees’ psychological empowerment. The study holds several implications for researchers and practitioners in the field.
Isolation and Purification of Endogenous Microorganisms from Shengli Lignite and Study on Its Ability to Dissolve Lignite
Authors: Zhao Yinglin , Chai Ruina , Duan Jianguo , Yang Zhiying , Zhang ShuHeng , Liu Yunying , Wang Xiaoxia , Cheng Jianguo 
Published: July 2024

Abstract

In order to make more effective use of the abundant lignite resources and to explore more possibilities for the application of lignite, this study describes the isolation of microorganisms from lignite and their dissolution and transformation effects on lignite. Microorganisms were isolated from Shengli lignite using the dilution plating method and the streak plate method, and their species identification was conducted. The lignite dissolution capability of each bacterial strain was tested. The research found that a total of 31 indigenous microorganisms were isolated from Shengli lignite, including 16 bacteria and 15 fungi, among which 9 bacteria and 6 fungi exhibited coal-dissolving effects, with varying degrees of effectiveness. Bacterium SH10 Lysinibacillus fusiformis and fungus L1W Paecilomyces lilacinus showed the best coal-dissolving capabilities. The products of lignite after microbial dissolution were analyzed using gas chromatography-mass spectrometry (GC-MS), revealing that high molecular weight lignite was decom-posed into a variety of small molecular organic compounds during the microbial coal dissolution process. These findings provide a good approach for the green and efficient utilization of lignite, indicating that the decomposition of lignite by microorganisms has a promising prospect for development.
Study on the Machining Accuracy of Soft Elastic Material Using Cryogenic Dicing
Authors: Yu Binhai , He Chonghui , Li Jiasheng , Zhang Yunlong , Ding Xinrui , Li Zongtao 
Published: July 2024

Abstract

Dicing is one of the common processing methods for soft elastic materials. However, as the processing dimensions continue to decrease, the machining accuracy of the workpiece becomes worse. In this work, a three-dimensional (3D) finite element model (FEM) of dicing processing is established by using finite element software ABAQUS and is compared with experimental results. Based on the established 3D dicing FEM, the influence of temperature, depth of cut, and spindle speed on the dicing process is studied. The results show that in the traditional soft elastic material dicing process, the increase in spindle speed and the decrease in processing dimensions led to the vibration of the tool, tilt and twist deformation of the workpiece, which become the main reasons for the poor machining accuracy. The application of cryogenic processing can effectively suppress the tilt and twist deformation of the workpiece. Under high spindle speed, cryogenic dicing can also somewhat mitigate the negative influence of tool vibration.
Barriers and Facilitators to Accessing Post Sexual-Based Violence Health Services among Young Women Attending Higher Education Institutions in Nigeria
Authors: Adebisi Ajoke Esther , Zhong Eric Chen , Adeagbo Oluwafemi , Badru Oluwaseun , Mogo Ebele R.I. , Yankam Brenda , Oreh Adaeze , Gadanya Muktar A. , Bain Luchuo Engelbert 
Published: July 2024

Abstract

Background
Post-sexual-based violence (SBV) services are imperative when it comes to attenuating SBV-induced consequences. These services are reportedly rare, and often underutilized, most especially by young women in Sub-Saharan Africa. This study aimed to explore the barriers and facilitators in accessing post-SBV services among young women (18–24 years) attending higher education institutions in Nigeria.
Methods
An online survey using a pre-tested and validated questionnaire was administered to a purposive sample of 114 respondents between the 8th and 22nd March 2022. Descriptive statistics were used to summarize the study findings.
Results
The majority (71.1%) of the respondents were between the ages of 21–24 years, and 8.5% of the respondents reported the nature of their first intercourse was not consensual. Half of the respondents (50.9%) strongly agreed that a post-SBV health service should be the first place to go following an incident of rape, but over half of the respondents (53.2%) reported a lack of awareness of existing SBV health services as a barrier that impacts young women’s access to these services. Also, less than half the respondents strongly agreed that healthcare workers can provide the highlighted post-SBV services in the study including emergency contraceptives to prevent pregnancy and Post Exposure Prophylaxis to prevent HIV (39.6% and 42.9% respondents respectively), showing awareness gaps. Other key barriers reported include stigma or shame, and lack of support systems. Key facilitators included an assurance of confidentiality and access to free Post-SBV health services.
Conclusion
Important barriers and facilitators impact access to post-SBV-health services in Nigeria, especially among young women. Multilevel efforts by families, civil society organizations, communities, and governments will help address these barriers and facilitate access to SBV health services.