bluuebunny/crossref_metadata_2025_split huggingface dataset:
Childhood trauma is associated with a specific admixture of affective, anxiety, and psychosis symptoms cutting across traditional diagnostic boundaries
Authors: van Nierop M. , Viechtbauer W. , Gunther N. , van Zelst C. , de Graaf R. , ten Have M. , van Dorsselaer S. , Bak M. ,   Genetic Risk and OUtcome of Psychosis (GROUP) investigators, van Winkel R. 
Published: October 2014

Background.Meta-analyses link childhood trauma to depression, mania, anxiety disorders, and psychosis. It is unclear, however, whether these outcomes truly represent distinct disorders following childhood trauma, or that childhood trauma is associated with admixtures of affective, psychotic, anxiety and manic psychopathology throughout life.Method.We used data from a representative general population sample (NEMESIS-2, n = 6646), of whom respectively 1577 and 1120 had a lifetime diagnosis of mood or anxiety disorder, as well as from a sample of patients with a diagnosis of schizophrenia (GROUP, n = 825). Multinomial logistic regression was used to assess whether childhood trauma was more strongly associated with isolated affective/psychotic/anxiety/manic symptoms than with their admixture.Results.In NEMESIS-2, largely comparable associations were found between childhood trauma and depression, mania, anxiety and psychosis. However, childhood trauma was considerably more strongly associated with their lifetime admixture. These results were confirmed in the patient samples, in which it was consistently found that patients with a history of childhood trauma were more likely to have a combination of multiple symptom domains compared to their non-traumatized counterparts. This pattern was also found in exposed individuals who did not meet criteria for a psychotic, affective or anxiety disorder and who did not seek help for subclinical psychopathology.Conclusions.Childhood trauma increases the likelihood of a specific admixture of affective, anxiety and psychotic symptoms cutting across traditional diagnostic boundaries, and this admixture may already be present in the earliest stages of psychopathology. These findings may have significant aetiological, pathophysiological, diagnostic and clinical repercussions.
Regionalism, activism, and rights: New opportunities for health diplomacy in South America
Authors: RIGGIROZZI PÍA 
Published: October 2014

AbstractTackling germs, negotiating norms, and securing access to medicines are persistent challenges that disproportionally affect developing countries' participation in global health governance. Furthermore, over the last two decades, the excessive focus on global pandemics and security in global health diplomacy, rendered peripheral diseases that usually strike the poor and vulnerable, creating situations of marginalisation and inequality across societies. However, as the importance of regions and regionalism increases in global politics, and integration ambitions and initiatives extend beyond trade and investment to embrace welfare policy, there are new opportunities to explore whether and how regional commitments affect health equity and access to medicine in developing nations. What, if any, are the possibilities for meso-level institutions to provide leadership and direction in support of alternative practices of global (health) governance? Can regional polities become international advocacy actors in support of global justice goals? This article addresses these questions by analysing regional health diplomacy in South America. The article argues that regional organisations can become sites for collective action and pivotal actors in the advocacy of rights (to health) enabling diplomatic and strategic options to member state and nonstate actors, and playing a role as deal-broker in international organisations by engaging in new forms of regional health diplomacy.
Young children use shared experience to interpret definite reference
Authors: SCHMERSE DANIEL , LIEVEN ELENA , TOMASELLO MICHAEL 
Published: October 2014

AbstractWe investigated whether children at the ages of two and three years understand that a speaker's use of the definite article specifies a referent that is in common ground between speaker and listener. An experimenter and a child engaged in joint actions in which the experimenter chose one of three similar objects of the same category to perform an action. In subsequent interactions children were asked to get ‘the X’ or ‘a X’. When children were instructed with the definite article they chose the shared object significantly more often than when they were instructed with the indefinite article in which case children's choice was at chance. The findings show that in their third year children use shared experiences to interpret the speaker's communicative intention underlying her referential choice. The results are discussed with respect to children's representation of linguistic categories and the role of joint action for establishing common ground.
Ind-abelian categories and quasi-coherent sheaves
Authors: SCHÄPPI DANIEL 
Published: October 2014

AbstractWe study the question of when a category of ind-objects is abelian. Our answer allows a further generalization of the notion of weakly Tannakian categories introduced by the author. As an application we show that, under suitable conditions, the category of coherent sheaves on the product of two schemes with the resolution property is given by the Deligne tensor product of the categories of coherent sheaves of the two factors. To do this we prove that the class of quasi-compact and semi-separated schemes with the resolution property is closed under fiber products.
Detection of Mycobacterium avium subspecies paratuberculosis in environmental samples by faecal culture and real-time PCR in relation to apparent within-herd prevalence as determined by individual faecal culture
Authors: DONAT K. , KUBE J. , DRESSEL J. , EINAX E. , PFEFFER M. , FAILING K. 
Published: October 2014

SUMMARYEnvironmental samples are a cost-saving and easy-to-use approach to diagnose paratuberculosis at the herd level. Detailed knowledge concerning its uncertainties in herds with a low prevalence of Mycobacterium avium spp. paratuberculosis (MAP) is required to design sampling strategies in control programmes. This study aimed to calculate a threshold level of the apparent within-herd prevalence (WHPapp) as determined by individual mycobacterial cultivation (faecal culture; FC) of all cows thus allowing the detection of a herd as MAP-positive at a certain probability level (Pd). Out of 200 environmental samples taken twice from five predefined locations in a barn, 25 were positive by FC and 60 were positive by a quantitative real-time PCR method (qPCR). A logistic regression model was used to calculate the WHPapp threshold of detection. For 50% Pd, a WHPapp threshold of 2·9% was calculated for the combination of three samples (milking area, main cow alleyways, holding pen) tested simultaneously both by FC and qPCR. The threshold increased to 6·2% for 90% Pd. Repeated environmental sampling did not reduce the WHPapp threshold. Depending on the particular needs for prevalence estimation or in control programmes (single or repeated sampling) the provided WHPapp thresholds at different Pd will enable decisions to be made about various sampling strategies.
Public health measures to control the spread of antimicrobial resistance inNeisseria gonorrhoeaein men who have sex with men
Authors: XIRIDOU M. , SOETENS L. C. , KOEDIJK F. D. H. , VAN DER SANDE M. A. B. , WALLINGA J. 
Published: October 2014

SUMMARYGonorrhoea is one of the most common sexually transmitted infections. The control of gonorrhoea is extremely challenging because of the repeated development of resistance to the antibiotics used for its treatment. We explored different strategies to control the spread of antimicrobial resistance and prevent increases in gonorrhoea prevalence. We used a mathematical model that describes gonorrhoea transmission among men who have sex with men and distinguishes gonorrhoea strains sensitive or resistant to three antibiotics. We investigated the impact of combination therapy, switching first-line antibiotics according to resistance thresholds, and other control efforts (reduced sexual risk behaviour, increased treatment rate). Combination therapy can delay the spread of resistance better than using the 5% resistance threshold. Increased treatment rates, expected to enhance gonorrhoea control, may reduce gonorrhoea prevalence only in the short term, but could lead to more resistance and higher prevalence in the long term. Re-treatment of resistant cases with alternative antibiotics can substantially delay the spread of resistance. In conclusion, combination therapy and re-treatment of resistant cases with alternative antibiotics could be the most effective strategies to prevent increases in gonorrhoea prevalence due to antimicrobial resistance.
Dose–response algorithms for water-bornePseudomonas aeruginosafolliculitis
Authors: ROSER D. J. , VAN DEN AKKER B. , BOASE S. , HAAS C. N. , ASHBOLT N. J. , RICE S. A. 
Published: October 2014

SUMMARYWe developed two dose–response algorithms forP. aeruginosapool folliculitis using bacterial and lesion density estimates, associated with undetectable, significant, and almost certain folliculitis. Literature data were fitted to Furumoto & Mickey's equations, developed for plant epidermis-invading pathogens:Nl = Aln(1 + BC) (log-linear model);Pinf = 1−e(−rcC)(exponential model), whereAandBare 2.51644 × 107lesions/m2and 2.28011 × 10−11 c.f.u./mlP. aeruginosa, respectively;C = pathogen density (c.f.u./ml),Nl = folliculitis lesions/m2,Pinf = probability of infection, andrC = 4·3 × 10−7 c.f.u./mlP. aeruginosa. Outbreak data indicates these algorithms apply to exposure durations of 41 ± 25 min. Typical water quality benchmarks (≈10−2 c.f.u./ml) appear conservative but still useful as the literature indicated repeated detection likely implies unstable control barriers and bacterial bloom potential. In future, culture-based outbreak testing should be supplemented with quantitative polymerase chain reaction and organic carbon assays, and quantification of folliculitis aetiology to better understandP. aeruginosarisks.
Q fever in China: a systematic review, 1989–2013
Authors: EL-MAHALLAWY H. S. , LU G. , KELLY P. , XU D. , LI Y. , FAN W. , WANG C. 
Published: October 2014

SUMMARYQ fever, first described in 1937, is a worldwide zoonosis caused byCoxiella burnetiithat has long been considered an under-reported and under-diagnosed illness. In China, the disease was initially reported in 1950 and in the last 25 years (1989–2013) there have been 29 reports on Q fever in China, nearly half of which were in the last 5 years. These publications have largely been in Chinese and in this review we summarize their findings to enable a better understanding of Q fever in China. The overall prevalence ofC. burnetiiinfections in the reports is 10% (1139/11 209) in people, 15% (288/1918) in cattle and 12% (176/1440) in goats. These infections occurred widely in China with positive people and/or animals reported in 64 cities/municipalities from 19 provinces, particularly those in the eastern, western and northern areas. Cattle and goats had the highest seroprevalences of all the domestic animals studied and a wide variety of ticks were found to be infected. Mice were also commonly infected and had high copy numbers ofC. burnetiiDNA, suggesting they might be important in the epidemiology of Q fever in China.
Affective Neuroscience and the Causes of the Mutiny of the French 82nd Infantry Brigade
Authors: ZIENTEK ADAM DEREK 
Published: October 2014

AbstractThis article seeks to demonstrate how some elements of affective neuroscience and basic emotions theory can be used to inform historical reasoning. It begins with an overview of contemporary basic emotions theory. It then provides a case study of the mutiny of the French 82nd Infantry Brigade, which took place on 1–2 June 1917, interpreting the events of the mutiny in the light of some tenets of basic emotions theory. It focuses specifically on how alcohol consumption among mutineers affected their experience of the basic emotions of fear and anger. Finally, it addresses some empirical and theoretical shortcomings of the approach and concludes tentatively that some elements of affective neuroscience and basic emotions theory can be useful to historians.
Opposing Scientific Cruelty: The Emotions and Sensitivities of Protestors against Experiments on Animals
Authors: TRAÏNI CHRISTOPHE 
Published: October 2014

AbstractAfter a marked decline, protests against cruelty to animals in scientific experiments acquired fresh momentum from the middle of the twentieth century onwards. This article sets out to show that the analysis of emotions and sensitivities is best able to account for the similarities and differences between historically distant mobilisations. While late twentieth-century activists have revived an emotional register invented by their precursors of the previous century, the meaning they attribute to their revolt has been profoundly transformed by sensitivities that derive from a very different social status and a different range of affective experiences.
Emotions, Moral Batteries and High-Risk Activism: Understanding the Emotional Practices of the Spanish Anarchists under Franco's Dictatorship
Authors: ROMANOS EDUARDO 
Published: October 2014

AbstractThis article studies the reactivation of activist networks in high-risk settings through a longitudinal analysis of the emotional practices of Spanish anarchists under Franco's dictatorship (1939–75). The anarchists mobilised a series of emotions in their discourse, seeking to change the degree and quality of emotions among potential supporters in order to inspire action. This emotion work focused on hope and indignation, which were crucial tools in the strategic framing of their movement. The use of hope in the anarchists’ discourse allowed them to positively evaluate the effectiveness of their challenge to the authorities. Furthermore, the activists participated in a strategic dramaturgy in front of domestic and international audiences with the intention of reproducing indignation in these onlookers and thus gathering support for their challenge to the regime. The combination of hope and indignation served as a moral battery during two periods of additional intensification of clandestine activity. Other emotions are also analysed, specifically, the resentment provoked by internal struggles in the middle of the 1940s, and the combination of anxiety and fascination towards the visibility achieved by the communists within the anti-Franco opposition in the early 1960s. In the end, longitudinal analysis of the anarchists’ emotional practices seeks to contribute to a better understanding of important questions still little studied in the emerging subfield of emotions and social movements, namely the combination of emotions in collective action and the historical evolution of the emotions.
Love, Peace and Rock ’n’ Roll on Gorky Street: The ‘Emotional Style’ of the Soviet Hippie Community
Authors: FÜRST JULIANE 
Published: October 2014

AbstractSoviet hippies were in many ways a paradoxical phenomenon. They imitated an ideal that was shaped by American realities in a Soviet world. They were anti-Soviet, yet they professed an apolitical life style. This article proposes that rather than looking at the Soviet hippies with ideology in mind it is more fruitful to consider them an emotional community whose ‘emotional style’ differed from the Soviet mainstream and ultimately proved a formidable challenge to the Soviet system. The article investigates several exterior markers of Soviet hippie culture, which formed and reflected the ‘emotional style’ of the Soviet hippies such as their creed of love and peace, their enjoyment of rock music and the significance of hippie fashion. Drawing on interviews with contemporary witnesses from the Soviet hippie scene particular attention is given to the new rhetoric hippies employed to describe emotions particular to their style of life, to the way the practice of these emotions differed from the official Soviet emotional codex and to the nexus that linked the vocabulary and practice of emotions with specific items, sites, rituals and attributes. The article concludes that, while Soviet hippies remained a subculture, their style, including their ‘emotional style’ proved very durable and capable of expansion into the mainstream, ultimately surviving the Soviet system and its emotional norms.
Anomalous origin of the right coronary artery from the posterior, non-coronary sinus of Valsalva diagnosed by cardiac magnetic resonance imaging
Authors: Adebo Dilachew , Jacobson Zev , Harris Matthew A. 
Published: October 2014

AbstractAnomalous origin of the right coronary artery from the posterior, non-coronary sinus is extremely rare and has never been reported in a paediatric-age competitive athlete. We report this very rare case of the right coronary artery arising from the posterior sinus. In the anomalous right coronary from the posterior sinus, the proximal right coronary artery appears widely patent and has no interarterial course.
Echocardiographic assessment of left ventricular dyssynchrony in Egyptian children with congestive heart failure due to dilated cardiomyopathy
Authors: Al-Biltagi Mohammed A. , Abd Rab Elrasoul Tolba Osama , El Mahdy Heba , Donia Amr , Elbanna Shaimaa 
Published: October 2014

AbstractObjective: To evaluate the presence of cardiac dyssynchrony in Egyptian children with congestive heart failure due to dilated cardiomyopathy. Materials and methods: A total of 30 children with congestive cardiac failure due to dilated cardiomyopathy and 30 healthy age-matched controls were examined with conventional echocardiography, tissue Doppler, and speckle tracking imaging. Results: Conventional Doppler echocardiography demonstrated significant left ventricular systolic and diastolic dysfunction in the patient group. Tissue Doppler showed significant decrease in S-wave velocity and E'/A' ratio, and prolonged isovolumic contraction and relaxation times of mitral annulus as well as significant prolongation in mean difference between time-to-peak systolic strain of the basal septal and basal lateral segments in the patient group compared with the control group (p<0.005). Speckle tracking imaging demonstrated significant prolongation in mean difference between time-to-peak systolic strain of anteroseptal and posterior segments in both circumferential and radial strain analysis in the patient group than in the control group (p<0.005). It also demonstrated significant prolongation in the mean difference between time-to-peak systolic strain of the basal septal and basal lateral segments in longitudinal strain analysis in the patient group than in the control group (p<0.005). A significant increase in the standard deviation of time-to-peak strain, as a marker of increased intra-ventricular dyssycnrony, was present in the patient group compared with the control group (p=0.008). Conclusion: Children with congestive heart failure due to dilated cardiomyopathy usually suffer from significant intra-ventricular dyssynchrony. Tissue Doppler imaging and speckle tracking imaging strain analysis are helpful tools to detect the presence of cardiac dyssynchrony.
Clinically stable type A aortic dissection: an unusual case
Authors: Özveren Olcay , Eroğlu Elif , Erdik Baran , Degertekin Muzaffer 
Published: October 2014

AbstractAcute type A aortic dissection is a catastrophic situation, often accompanied by aortic regurgitation. A rarely described cause of aortic regurgitation, in this clinical scenario, is the prolapse of an intimal flap into the left ventricular outflow tract. We present here a case of acute type A aortic dissection with a circumferential intimal flap, prolapsing into the left ventricular outflow tract and causing massive aortic regurgitation.
Patients' priorities for treatment decision making during periods of incapacity: quantitative survey
Authors: Rid Annette , Wesley Robert , Pavlick Mark , Maynard Sharon , Roth Katalin , Wendler David 
Published: October 2014

AbstractObjective:Clinical practice aims to respect patient autonomy by basing treatment decisions for incapacitated patients on their own preferences. Yet many patients do not complete an advance directive, and those who do frequently just designate a family member to make decisions for them. This finding raises the concern that clinical practice may be based on a mistaken understanding of patient priorities. The present study aimed to collect systematic data on how patients prioritize the goals of treatment decision making.Method:We employed a self-administered, quantitative survey of patients in a tertiary care center.Results:Some 80% or more of the 1169 respondents (response rate = 59.8%) ranked six of eight listed goals for treatment decision making as important. When asked which goal was most important, 38.8% identified obtaining desired or avoiding unwanted treatments, 20.0% identified minimizing stress or financial burden on their family, and 14.6% identified having their family help to make treatment decisions. No single goal was designated as most important by 25.0% of participants.Significance of Results:Patients endorsed three primary goals with respect to decision making during periods of incapacity: being treated consistent with their own preferences; minimizing the burden on their family; and involving their family in the decision-making process. However, no single goal was prioritized by a clear majority of patients. These findings suggest that advance care planning should not be limited to documenting patients' treatment preferences. Clinicians should also discuss and document patients' priorities for how decisions are to be made. Moreover, future research should evaluate ways to modify current practice to promote all three of patients primary goals for treatment decision making.
‘The fugitive’: The figure of the judge in Coase's economics
Authors: BERTRAND ELODIE 
Published: October 2014

Abstract:‘The Problem of Social Cost’ (Coase, 1960) asserts a normative role for the common law judge, that of taking into account the economic consequences of his decisions in allocating property rights. This position is often accused of inconsistency: Coase sees the figure of the judge as willing and able to improve economic efficiency, but criticises the actors of public intervention, particularly regulators, for being fallible, vulnerable to political pressures, and lacking information. I shall show that Coase's giving this role to the judge stems precisely from his criticism of public intervention. This means that his figure of the judge escapes the tenets of the theoretical system that first rendered it necessary. Various reasons could explain this difference of treatment as between the judge and the other figures of public intervention in Coase's system, but Coase makes too strong an opposition between common law on one side and regulatory and statutory law on the other, and leaves unexplained the motivation of judges.