bluuebunny/crossref_metadata_2025_split huggingface dataset:
Audit Keputusan Manajemen Atas Pilihan Membeli, Menyewa Dan Meleasing Kendaraan Angkutan Pada Cv. Karya Mina Pematang Bandar
Authors: Tambunan Nasir Arafik , Damanik Elfina Okto Posmaida , Eva Sriwiyanti  
Published: August 2024

Terdapat tiga (3) alternatif pilihan dalam menyediakan kendaraan angkutan pada CV. Karya Mina Pematang Bandar yaitu membeli, menyewa dan meleasing kendaraan. Tujuan penelitian iniuntuk melihat apakah pilihan CV. Karya Mina Pematang Bandar yang selama ini dalam membeli kendaraan angkutannya dengan meleasing sudah pilihan yang ekonomis. Penelitian ini merupakan penelitian kuantitatif dengan pendekatan studi kasus. Metode penelitian yang digunakan adalah observasi, wawancara dan dokumentasi. Metode analisis yaitu: audit pendahuluan; review dan pengujian; audit terinci dan pelaporan.Berdasarkan hasil penelitian, diketahui bahwa jumlah biaya yang dikeluarkan membeli mobil angkutan secara cash adalah alternatif yang paling ekonomis yaitu lebih rendah Rp.74.810.000 dari alternatif meleasing dan lebih rendah Rp.427.236.000 dari alternatif menyewa
PELATIHAN PEMERIKSAAN SADARI DI PCA KRATON D.I. YOGYAKARTA
Authors: Dwi Ernawati Dwi Ernawati , Wahyuntari Evi 
Published: August 2024

Perempuan memiliki resiko terkena kanker payudara yang bisa penyebab kematian paling umum. Data empiris menunjukkan bahwa kejadian kanker meningkat seiring bertambahnya usia, namun usia muda tidak menjamin keamanan terhadap kanker payudara. Tujuan dari kegiatan pengabdian kepada Masyarakat ini adalah untuk meningkatkan pengetahuan perempuan tentang pencegahan kanker payudara sejak dini sehingga meningkatkan kesadaran untuk rutin menjalani SADARI. Metode yang digunakan diawali dengan pemaparan informasi, demonstrasi dan latihan pelaksanaan SADARI. Hasil yang didapat dalam kegiatan pengabdian kepada masyarakat ini yaitu terjaringnya peserta sebanyak 127 orang. Peserta yang bersedia untuk melakukan sadari dengan bimbingan ada 15 orang, dan hasil pemeriksaan SADARI 10 orang tersebut dalam kondisi normal. Simpulan Simpulan Pengurus PCA Kraton sudah mampu untuk melakukan deteksi dini kanker payudara sendiri dengan Teknik yang benar.
Kata kunci : Sadari, PCA Kraton, Perempuan, Kanker Payudara
Frequency of branching pattern variation of the renal artery in a subset of Karachi population: A Study on Multi-Detector Computed Tomography
Authors: Mohiuddin Maria , Khan Rosheena Nabeel , Ahmed Syeda Bushra , Lakhani Mubina , Sughra Amatul , Hassan Nuzhat 
Published: August 2024

Abstract
Objective: This study was conducted to determine the frequency of early branching patterns of renal arteries in a subset of Karachi.
Method: This was a cross-sectional study, conducted in Ziauddin University Hospital, Clifton campus, Karachi. This was a prospective study conducted from June 2017 to July 2018. The sample size was calculated by using a 95 % confidence interval and study participants were included through consecutive sampling. A total of 250 participants (500 kidneys) aged 21 to 60 years and serum creatinine of ≤ 1.3 mg /dl were included in the study. All CT examinations were performed on an MDCT scanner (Alexion 16 slicer, Japan) in the arterial phase.
Results: In this study, among a total of 250 study participants, 52 % (129 out of 250) were males and 48 % (121 out of 250) were females. Out of a total of 250 study participants, renal artery variation of pre-hilar early branching was found to be 9.2% (23) in individuals. On the right side early was found to be 4% and 5.2%. The length of the main renal artery in early branching measured was 11.0 ± 2.05 mm.
Conclusion: This study concluded that the frequency of early branching of renal arteries was 9.2% in a subset of the Karachi population.
Prognostic Significance of Admission CRP Levels as a Predictor of Mortality in Burn Patients
Authors: Syed Maria , Jehangir Qaiser , Shah Ijaz Hussain , Siddiqui Sana Shaukat , Ishaq Sara , Zaka Sarah 
Published: August 2024

Objective: The objective of this study is to evaluate CRP's value as a biomarker of mortality in burn victims admitted to a burn unit.
Method: This prospective longitudinal observational study investigates the association between C-reactive protein (CRP) levels at admission and mortality in burn patients. Data were collected from 48 patients admitted to Sheikh Zayed Hospital between 16.02.2023 and 15.08.2023, focusing on demographics, burn characteristics, and laboratory findings. The study employed non-probability consecutive sampling and excluded individuals with certain medical histories. Descriptive statistics, correlation analyses, and logistic regression were used to explore the relationship between CRP levels and mortality, considering potential confounders.
Results: In a study of 48 burn patients, 87.5% survived, while 12.5% did not. Non-survivors had significantly higher total body surface area burned (41.3% vs 22.7%) and elevated C-reactive protein (CRP) levels at admission (23.5 mg/L vs 10.6 mg/L) compared to survivors. Electric and 4th-degree burns, fever at admission was higher, and hospital stays were shorter for non-survivors. No significant differences were found in age and gender. A strong positive correlation was observed between total burn surface area and CRP at admission. Logistic regression revealed significant predictors of mortality, with CRP at admission showing substantial significance (SE = 8.893, p = 0.012, Exp(B) = 1.657, 95% CI [.000, .000]).
Conclusions: The results showed that CRP level at admission was a significant predictor of mortality among burn victims. This study concluded CRP levels might be a helpful biomarker for determining the severity of burns and projecting patient outcomes. Future research should address the identified limitations to strengthen the evidence base on CRP's prognostic value in burn injuries.
Comparative Analysis of Barriers and Challenges in Adoption of Electronic Health Record System in Government and Private Hospitals of Islamabad
Authors: Jawwad Ghazala , Asim Maleha , Ali Amanat , Khan Humaira Fayyaz , Anjum Aiman Farogh , Arain Abdul Qudoos 
Published: August 2024

Objective: The purpose of this study was to identify the barriers and challenges in adoption of the EHR system in hospitals of Islamabad and to compare the barriers and challenges faced in adopting and running of electronic health record system in government and private hospitals of Islamabad.
Materials and Methods: This multicentric cross-sectional study was carried out among 160 health providers of four government and four private hospitals in Islamabad from June 2022 to November 2022. A structured questionnaire was distributed to the management, health professionals and the staff using EHR system by simple random sampling. Data were analyzed using SPSS version 26. Independent sample t test was applied for comparative analysis of challenges and barriers in government and private hospitals.
Results: The response rate for the electronic health record system survey was 160 (76%). Of those responding, 85.75% and 72% reported use of EHR system regarding patient care from government and private hospitals respectively. Around 42.5% and 83.75% government and private hospitals have fully functional EHR system and 72% from government and 90% responses from private reported use of computers as a major mode of patients’ data entry. Significant difference was found between government and private hospitals regarding social and legal barrier and lack of knowledge of EHR system (p value <0.05). Implementation of single module and multi module was a big challenge for government and private hospital respectively (p value <0.05).
Conclusion: Government and private hospitals equally face the challenges and barriers tin implementation of EHR system with some barriers and challenges more prevalent in private hospitals and some in government hospitals.
Patterns Of HRCT In Patients with Pulmonary Tuberculosis At A Tertiary Care Hospital
Authors: Anwar Sohail , Nawaz Arsalan , Moinuddin Imran Ahmed , Kashif Muhammad , Mumtaz Asim , Bhatti Muhammad Ijaz 
Published: August 2024

Abstract:
Background:
With the advancement in biomedical engineering and imaging technology, HRCT scan has emerged as more effective tool than standard1computed tomography scan & traditional chest radiography in detecting pulmonary pathologies including pulmonary tuberculosis.
Objective:
To determine different patterns of HRCT in patients with pulmonary tuberculosis.
Study Design: Retrospective observational study.
Setting: Department of Pulmonology & Internal Medicine, University of Lahore Teaching Hospital, Lahore.
Methodology:
Total of 76 patients were included in the study based on inclusion & exclusion criteria, selected by non-probability consecutive sampling. Demographic information, signs & symptoms and results from high-resolution tomography scans were noted. Data analysis was performed on SPSS 23 & reported by descriptive statistics.
Results:
Total 76 patients were included. The mean age was 46.18+20.27 years ranging from 8 to 86 years. There were 43(56.6%) males and 33(43.4%) females. 36 (47.37%) patients were up to 45 years of age and 40 (52.63%) patients were above 45 years.
Signs and symptoms of pulmonary TB were cough 60 (78.9%), sputum 21(27.6%), fever 43(55.3%), night sweats 23(30.3%) & weight loss 36(47.4%). Most common HRCT pattern observed was ill defined nodules (77.6% cases) while atelactasis was the least common HRCT pattern observed (22.4% cases).
There was no statistically significant difference (P <0.05) observed between different patterns of HRCT and positive sputum smear.
Conclusion:
Our study concluded that a HRCT scan is helpful in the identification of the disease and its accompanying spectrum in patients with pulmonary tuberculosis with nodules being the most prevalent HRCT pattern.
Key Words:
Tuberculosis (TB), High resolution computerized tomography (HRCT)
Targeting Liver Biopsies For Optimal Biopsy Site In Diffused Liver Disease Using Real-Time Shear Wave Elastography: A Prospective, Single Center Study
Authors: Malik Naushaba , Aftab Shahbakht , Noor Rida , Aftab Noor , Rizwan  , Rehan  
Published: August 2024

Objective: The study aimed to pinpoint the precise site for liver biopsy using ultrasound and elastography guidance and to assess and compare the diagnostic accuracy of shear wave elastography (SWE) and transient elastography (TE) through histopathological correlation.
Methodology: In this prospective single-centre study, the researchers divided the participants into two groups. One group (Group A) had their biopsy guided by ultrasound, which is a standard imaging technique. The other group (Group B) had their biopsy guided by a newer technique called elastography. For the group with elastography-guided biopsy, the researchers used this technique to find the stiffest part of the liver before taking the biopsy sample.
Results: The study investigated how stiffness throughout the liver (mean liver stiffness) compared to stiffness measured in the biopsy samples (biopsy segment velocities). Even though the overall stiffness didn't differ much between different sections of the liver, the stiffness measured in the biopsy samples itself did vary. This suggests scarring (fibrosis) may not be evenly distributed throughout the liver. There was a strong link between the stiffness measured in the biopsy samples and the overall average stiffness. The traditional technique (TE) worked well for identifying moderate and severe stages of scarring (F2, F3, and F4). The new sound wave technique (SWE) was good at identifying moderate fibrosis (F2) but less accurate for mild stages (F1). However, it performed similarly to the traditional technique for moderate to severe stages (F2 and F3). The new technique (SWE) could distinguish between mild or no scarring and moderate/severe scarring with good accuracy (over 95%) if the stiffness measured by the sound waves was at least 1.92 meters per second (m/s).
Conclusions: This study compared a new sound wave technique (SWE) to a traditional method (TE) for diagnosing liver scarring (fibrosis) in people with chronic liver disease. The findings suggest that the new technique is just as accurate as the traditional one for diagnosing moderate and severe scarring stages. Importantly, the study also found that scarring may not be evenly distributed throughout the liver. This is why the new sound wave technique, done at the time of biopsy, may be helpful. It can potentially help doctors pinpoint the best location for the biopsy sample, which could lead to more accurate diagnoses.
Evaluation of Jati (Jasminum grandiflorum L.) mouthwash and Jati Kwatha (decoction) in Mukhapaka (aphthous stomatitis): An open-label, randomized, placebo-controlled clinical study
Authors: Balakrishnan Geethu , Mohanan Arun , Ramesh N. V. 
Published: August 2024

Abstract

Background:
Leaf extract of Jati (Jasminum grandiflorum L.) has been proven to possess dermal wound healing and anti-ulcer activities. Mukhapaka (aphthous stomatitis) is the most common lesion of the oral cavity. For its management, Jati mouthwash was formulated by the Arka (distillation), and its efficacy was compared with the traditional form of Jati Kwatha (decoction). Due consideration was given to patient compliance, convenience of usage, increased shelf-life, no preservative, easy storage, and dispensing.

Aims:
The aim of this study was to evaluate the efficacy of Jati mouthwash and Jati Kwatha Kavala (gargle) in the management of Mukhapaka. ]

Materials and methods:
Forty-five patients having the classical symptoms of Mukhapaka were randomized into three groups as Jati mouthwash (group 1), Jati Kwatha Kavala (group II), and placebo (group III), all preparations were administered twice daily for seven days. The assessment was done by scoring method evaluating the oral ulcer activity, ulcer-related pain and functional disability, and Visual Analog Scale (VAS) at the baseline each day. Statistical evaluation was done within groups using paired t-test and between the groups using ANOVA post hoc multiple comparisons – Tukeys test.

Results:
Significant reductions was observed in VAS score for pain and other symptoms in the Jati mouthwash group at the end of seven days. Furthermore, the mouthwash group noted an accelerated mean healing period. Gas chromatography–mass spectrometry spectrum of the drug in its modified form as distillate revealed the presence of thymol and carvacrol, which are proven effective against oral pathogens but were absent in the Kwatha.

Conclusion:
Although the disease is self-limiting and the management is supportive, the Jati mouthwash was found to be better than its classical form of Kwatha or decoction.
Dip eyes in water technique (Akshi Nimanjjana): Efficacy of a simple technique in the management of meibomian gland dysfunction
Authors: Maheshwari Puneet , Gopalani Ajay , Gopalani Meena , Rahim MSG Ram 
Published: August 2024

Abstract

Background:
Dip eyes in water (DEW) is an ancient technique to improve eye hygiene. Conventionally, the eyes are cleaned by splashing water on them. However, splashing is not very effective as the eyes get closed reflexly when the water is splashed onto the eyes. On the other hand, in the DEW technique, it is conveniently possible to keep eyes fully open when dipped inside the water in the eye cup. Meibomian gland dysfunction (MGD) is a chronic, frustrating disease for which there is no gold standard, and eye hygiene is presumed to play an important role.

Aim:
The present study was tested in a cohort of MGD patients using the DEW technique.

Materials and methods:
DEW was prescribed to seven patients who were symptomatic for a period ranging from 6 months to 2 years. The main four symptoms were irritation in the eyes, persistent watering of the eyes, burning sensation, and foreign-body sensation. The scale of assessment of these four symptoms was severe (+++), moderate (++), mild (+), and no symptoms (−). The outcome assessment criteria were complete relief in these four symptoms and were assessed after 1 year of starting treatment. The DEW technique was performed 3–4 times per day. It was added to the ongoing conservative treatment. Once complete relief was obtained, other conservative management measures were stopped, and only the DEW treatment continued. It was advised that the DEW treatment be continued as a part of the regular eye hygiene daily routine.

Results:
Five out of seven patients reported complete relief in outcome criteria (four symptoms), one had partial relief, and there was no relief in one of the patients. After a follow-up of 1 year, one patient (the one with partial relief) was lost to follow-up. Five out of seven patients had significant relief, and 5/6 patients had sustained relief on long-term follow-up. No adverse effects were reported by any of the patients.

Conclusion:
The DEW technique is promising in providing significant relief in patients with MGD. The encouraging results of DEW in this series can help prescribe and extend the indications of DEW in managing MGD and other eye disorders, in which eye hygiene plays a therapeutic role and as a daily routine eye-care practice to prevent various eye disorders.
Clinical evaluation of capsule BP Norm in the management of essential hypertension: A preliminary open-label parallel group study
Authors: Tanna Ila Revachand , Goyal Mandip , Chandola Hari Mohan 
Published: August 2024

Abstract

Background:
Since hypertension is so common and a major risk factor for cardiovascular illnesses and other complications, it is both a significant public health issue and an important topic of research. Hence, a clinical trial was planned.

Aims:
To evaluate the role of herbal preparation capsule BP Norm containing dry extract of Bhringraja (Eclipta alba (L) Hassk.), Haritaki (Terminalia chebula Retz.), Ashwagandha (Withania somnifera (L.) Dunal), Shankhpushpi (Convolvulus pluricaulis), and Sarpagandha (Rauwolfia serpentina [L.] Benth. Ex Kurzc) in newly diagnosed cases and in combination with allopathic antihypertensive drugs in the uncontrolled cases of essential hypertension.

Materials and methods:
A total of 103 patients meeting the seventh report of the Joint National Committee on the Prevention, Detection, Evaluation, and Treatment of High Blood Pressure criteria of essential hypertension (EHT) of age group 20–65 years of either sex participated in the study. Newly diagnosed cases who were not taking any antihypertensives were administered capsule BP Norm (250 mg), two capsules twice daily for 1 month, whereas uncontrolled cases of essential hypertension (systolic blood pressure [SBP] >140 mmHg and <200 mmHg and/or diastolic blood pressure [DBP] >90 mmHg and <120 mmHg) were administered 1 capsule of BP Norm (250 mg) twice daily with water in addition to continuing allopathic antihypertensive drugs for 1 month. The assessment was made through various variables such as SBP, DBP, chief complaints, associated complaints, Hamilton anxiety rating scale (HARS), Hamilton rating scale for depression (HRSD), lipid profile, and serum creatinine.

Results:
Capsule BP Norm produced highly significant reduction in both the SBP (16.82%, P < 0.001) and DBP (13.71%, P < 0.001) of newly diagnosed patients as well as in the SBP (18.49%, P < 0.001) and DBP (13.95%, P < 0.001) of uncontrolled cases (EHT). Capsule BP Norm provided significant relief in clinical features of EHT, HARS, and HRSD in both groups.

Conclusion:
Capsule BP Norm has promising antihypertensive effects in newly diagnosed cases as well as synergistic effects when combined with allopathic antihypertensive drugs in uncontrolled cases of essential hypertension.
Assessment of endothelial cell density after deep anterior lamellar keratoplasty
Authors: Ebied Ahmed H. , Khalil Hossam-Eldein M.A. , Haroun Hazem E. , Elbeih Islam F.A. , Saif Ahmed T.S. 
Published: August 2024

Background
The fundamental aim of successful Keratoplasty is to obtain a clear corneal graft and to maintain its survival. Previous studies have demonstrated the importance of endothelial cell density (ECD) in maintaining graft transparency and survival after keratoplasty.

Objective
This study aimed to assess the changes in corneal ECD following deep anterior lamellar keratoplasty (DALK) and to evaluate its visual and surgical outcomes.

Patients and methods
This prospective observational study was conducted at the National Eye Institute Rod-Elfarag, Cairo, Egypt, between July 2020 and February 2022. It included 50 eyes of 50 patients, with pathologies affecting the epithelium and/or stroma for whom DALK was performed. Patients with comorbidities affecting the endothelium were excluded from the study. Preoperative, intraoperative, and postoperative data, including ECD, were collected. Postoperative assessments were conducted at 1, 3, and 6 months.

Results
The mean age of the patients was 24.80±2.81 years (range=21–30 years), with 60% of the patients being males. The preoperative diagnoses included keratoconus, granular dystrophy, macular dystrophy, and corneal scarring. The ECD significantly decreased from a baseline value of 2726.6±188.53 cells/mm2 to 2591±175.79 cells/mm2 at 1 month, 2461.3±155.43 cells/mm2 at 3 months, and to 2349.9±104.58 cells/mm2 at 6 months postoperatively (P<0.001). The best corrected visual acuity improved significantly from a preoperative value of 0.06±0.02 to 0.61±0.15 at 6 months, postoperatively (P<0.001). The postoperative complications included a double anterior chamber (in 2 eyes) and wrinkling of Descemet’s membrane (in 2 eyes).

Conclusion
DALK led to a significant reduction in ECD over the first 6 months postoperatively, with improvement in best corrected visual acuity. The study highlights the importance of considering ECD changes and visual outcomes in DALK patients. Preservation of the patient’s endothelium may contribute to better long-term outcomes, with careful consideration of the potential complications.
Exploring Ultra-short Heart Rate Variability Metrics in Patients with Diabetes Mellitus: A Reliability Analysis
Authors: Srivastav Shival , Gadhvi Mahesh Arjundan , Shukla Ravindra Gayaprasad , Bhagat Om Lata 
Published: August 2024

AbstractObjectives:Ultra-short heart rate variability (HRV) metrics represent autonomic tone parameters derived using small epochs of interbeat interval data. These measures have risen in popularity with the advent of wearable devices that can capture interbeat interval data using electrocardiography (ECG) or photoplethysmography. Autonomic neuropathy in diabetes mellitus (DM) is well established, wherein 5-min HRV is conventionally used. Ultra-short measures have the potential to serve as markers of reduced autonomic tone in this patient population.Methods:Data of patients with Type I and Type II DM who had presented to our laboratory for autonomic neuropathy assessment were chosen for analysis. One-minute and 2-min epochs were chosen from 5 min of ECG data using standard software. Time domain, frequency domain, and nonlinear measures were computed from 1 to 2 min epochs, and reliability was compared with measures derived from 5-min HRV using intraclass correlation coefficients (ICCs).Results:Data of 131 subjects (79 males, 52 females; mean age = 53.3 ± 12.16 years) were analyzed. All ultra-short HRV measures derived from 1 min to 2 min data showed good to excellent reliability (median ICC values ranging from 0.83 to 0.94) when compared with 5-min metrics. The notable exception was very low frequency (VLF) power, which showed poor reliability (median ICC = 0.43).Conclusions:Ultra-short HRV metrics derived from 1 to 2 min epochs of ECG data can be reliably used as predictors of autonomic tone in patients with DM. VLF power is poorly reproducible in these small epochs, probably due to variability in respiratory rates. Our findings have implications for ultra-short HRV estimation using short epochs of ECG data.