bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengembangan Bioplastik Hidrofobik Berbasis Nanoselulosa Kulit Biji Kakao (Theobroma cacao L.) Dengan Metode Coating
Authors: Riskan Aditya 
Published: July 2024

Penelitian ini dilatarbelakangi oleh adanya limbah kulit biji kakao yang belum dimanfaatkan secara maksimal Kulit biji kakao memiliki kandungan selulosa yang cukup tinggi sehingga dapat dijadikan suatu alternatif untuk membuat produk baru turunan selulosa yaitu nanoselulosa. Nanoselulosa merupakan polimer selulosa yang berukuran nano. Nanoselulosa dapat dimanfaatkan dalam pengembangan bioplastik ramah lingkungan. Bioplastik kulit biji kakao masih memiliki kelemahan yaitu mudah menyerap air dari lingkungannya. Metodecoating dengan menggunakan Fluoro Octhyltriethoxyl Silane (FOS) dan lilin lebah diharapkan dapat menahan uap air dari lingkungan. Penelitian ini bertujuan untuk mengetahui perbandingan karakteristik selulosa, bleached selulosa dan nanoselulosa kulit biji kakao, serta mengetahui pengaruh konsentrasi pelapisan menggunakan FOS dan menggunakan lilin lebah terhadap karakteristik morfologi dan nilai sudut kontak dari bioplastik. Penelitian ini menggunakan Rancangan Acak Lengkap (RAL) dua faktor tanpa interaksi. Faktor pertama mencangkup perbedaan jenis bahan, terdiri atas dua taraf yaitu menggunakan FOS (F) dan lilin lebah (L). Faktor kedua merupakan jumlah pencelupan (P) terdiri atas tiga taraf yaitu 1 kali, 2 kali, dan 3 kali. Data yang diperoleh dianalisis secara deskriptif dan kuantitatif. Hasil analisis menunjukkan terjadi perbedaan karakteristik selulosa, bleached selulosa dan nanoselulosa kulit biji kakao. Analisis morfologi menunjukkan permukaan bioplastik yang lebih halus dengan perlakuan pelapisan dibandingkan tanpa perlakuan pelapisan. Analisis sudut kontak menunjukkan nilai sudut kontak yang lebih besar pada permukaan bioplastik dengan perlakuan pelapisan.
Exploring the Role of Social Norms in Buprenorphine Prescribing among Providers in a Rural Health System
Authors: Nanda Michelle A , Terry Danielle L , Marshall Corina 
Published: July 2024

Background: The opioid epidemic in the United States continues to accelerate, with opioid-related deaths increasing 30% from 2019 to 2021. Though medication assisted therapy (MAT) is an effective strategy for the treatment of opioid use disorder (OUD), utilization of this tool remains low, particularly in rural health settings. The aims of this study were (a) to examine perceived barriers to using MAT in a sample of rural health providers, (b) to examine the accuracy of medical providers’ perceptions of descriptive (eg, frequency) and injunctive (ie, approval of) norms related to the use of buprenorphine, and (c) to determine whether greater self-other differences predict greater likelihood of prescribing buprenorphine. Methods: An anonymous electronic survey was sent to 775 rural medical providers (response rate = 9.7%). Results: Results indicated that most providers do not prescribe buprenorphine or do so infrequently. Providers inaccurately believed that they were more accepting than their peers with regards to providing addiction care. Providers who assumed that peers were prescribing buprenorphine more often and were more accepting of it were more likely to engage in this practice themselves. Conclusions: These findings lay the groundwork for testing norms interventions that might enhance the uptake of the use of evidence-based substance use treatment by rural medical providers.
VARIOUS ORIGINS PNEUMONIA EXPRESS DIAGNOSIS DURING THE WAR IN UKRAINE
Authors: Koliada Oleh M. , Tynynyka Lyudmila M. , Koliada Tetyana I. , Nikolchenko Andrii Yu. , Legach Yevgen I. , Globa Vyacheslav Yu. , Legach Sergiy Ye. 
Published: July 2024

Introduction. The study of the serum level of PCT and sTREM has been proposed as markers of bacterial infection, which have been applied for the early differentiation of processes of viral and bacterial etiology.
Aim. Determination of express markers for predicting the effectiveness of empiric antibiotic therapy in patients with IPD.
Materials and methods. Study groups with viral pneumonias, as well as bacterial etiology caused by Haemophilus influenzae, groups of patients with ChOPd I-II III- IV stages were formed. Controls for the studied groups were patients at the stage of remission and a group of healthy individuals without lung pathology and infectious diseases. The specific identification of microorganisms in the clinical material of patients with pneumonia was carried out in two stages: the first stage in the laboratories of the respective hospitals was carried out by the method of HIR and CFT; the second was carried out with the help of specific antibodies by the indirect fluorescence method using a fluorescent microscope and qualitative analysis test kits («Respiratory Tract Profile 1 BIOCHIP Mosaics for infectious serology», Medizinische Labordiagnostika AG «EUROIMMUN»).
Results. In our study, the serum level of sTREM-1 was used as a criterion for assessing the probability of bacterial infection and, accordingly, increasing the degree of reliability of the prognosis provided by the PCT level study. The expression level of sTREM-1 and PCT were used as markers of bacterial infection for the early differentiation of processes of viral and bacterial etiology.
Conclusions. The study of serum levels of PCT and sTREM, which are markers of bacterial infection and are used for early differentiation of processes of viral and bacterial etiology, has demonstrated the prognostic importance of the express assessment method of the infectious process etiology. The obtained results were used in the development of method for predicting the effectiveness of empiric antibiotic therapy in patients with IPD infectious diseases.
IMPROVEMENT OF INSTRUMENTAL DIAGNOSTICS OF NODAL PATHOLOGY OF THE THYROID GLAND
Authors: Zinchenko Natalia I. , Khoperi Victoria G. 
Published: July 2024

Aim. Increasing the efficiency of fine-needle aspiration biopsy (FNA) of thyroid nodules at the pre-analytical stage by optimizing biopsy technology under ultrasound control.
Materials and methods. The material for the study was the results of TAP of thyroid nodules of 1960 patients (aged 16 to 82 years). All patients in the period 2015-2022 underwent FNA of nodular formations of the thyroid gland on the basis of the Department of X-ray and Functional Diagnostics with Ultrasound Studies of the Medical Center of the SIS "RPC PCM" SAD.
FNA was performed by ultrasound doctors of the highest qualification category using a biopsy gun and exclusively under ultrasound control. Sonographic criteria proposed by the ATA (American Thyroid Association) were used to determine the indications for FNA. For 402 patients, biopsy was performed under ultrasound control and without assessment of aspirate adequacy during manipulation. For 1,552 patients during the biopsy an express cytological method was used to assess the adequacy of aspirates, which was performed by an ultrasound doctor who had mastered the technique of preliminary cytological analysis. The efficiency of both methods was compared according to the criterion of informativeness of the obtained cytomorphological material.
Results. In total, among 1,960 cases of FNA of thyroid nodules, cytological results were not informative in 55 cases (2.81%). In the FNA group without express cytological analysis (402 cases), uninformative cytological results were found in 49 cases (12.19%), and with the use of express cytological analysis during biopsy (1558 cases), uninformative cytological findings were found in only 6 patients (0.39%).
Conclusions. The application of the optimized technology of FNA of thyroid nodules under ultrasound control with express cytology of aspirate by an ultrasound doctor increases the informativeness of the method and the economic component of FNA.
Penerapan Good BUMDes Governance
Authors: Hirman Akhmad Akram , Sukirman Anna Sutrisna , Bangun Andrye Ferndinand , Ramadhonah Isnani So'matur 
Published: July 2024

Good BUMDes Governance (GBG) adalah sebuah sistem pengelolaan yang berfokuskan kepada BUMDes (Badan Usaha Milik Desa) yang dirancang untuk meningkatkanÂ kinerja BUMDes, melindungi stakeholder terkhsusus warga desa, dan meningkatkan kepatuhan terhadap Peraturan Pemerintah No 11 tahun 2021 tentang BUMDes mengenai pembentukan BUMDes, pengeloaan BUMDes, serta jenis usaha dikembangkan nantinya. Penelitian ini bertujuan untuk terciptanya keberhasilan atas penerapan Good BUMDes Governance pada BUMdes XYZ. Penerapan GBG berupa penggunaan prinsip TARIF (Transparansi, Akuntabilitas, Responsibilitas, Independen dan Fairness) terhadap tata kelola di BUMDes XYZ. Teknik pengumpulan data ini menggunakan wawancara maupun observasi langsung kepada pihak terkait. Hasil dari penelitian ini menunjukkan BUMDes XYZ sudah menerapkan prinsip GBG akan tetap belum maksimal dikarenakan banyaknya kendala dihadapin pengurus BUMDes XYZ salah satunya tidak adanya laporan keuangan maupun kegiatan pada pengurus sebelumnya..
The MindMoves Trial: Cross-Sectional Analyses of Baseline Vascular Risk and Cognition in Older Women with Cardiovascular Disease
Authors: Halloway Shannon , Volgman Annabelle Santos , Barnes Lisa L. , Schoeny Michael E. , Wilbur JoEllen , Pressler Susan J. , Laddu Deepika , Phillips Shane A. , Vispute Sachin , Hall Gabriel , Shakya Shamatree , Goodyke Madison , Auger Claire , Cagin Kelly , Borgia Jeffrey A. , Arvanitakis Zoe A. 
Published: July 2024

Background: Vascular diseases, including atherosclerotic cardiovascular disease (ASCVD) and stroke, increase the risk of Alzheimer’s disease and cognitive impairment. Serum biomarkers, such as brain-derived neurotrophic factor (BDNF), vascular endothelial growth factor (VEGF), and insulin-like growth factor 1 (IGF-1), may be indicators of cognitive health. Objective: We examined whether vascular risk was associated with levels of cognition and serum biomarkers in older women with cardiovascular disease (CVD). Methods: Baseline data from a lifestyle trial in older women ( n = 253) with CVD (NCT04556305) were analyzed. Vascular risk scores were calculated for ASCVD (ASCVD risk estimator) and stroke (CHA2DS2-VASc) based on published criteria. Cognition-related serum biomarkers included BDNF, VEGF, and IGF-1. Cognition was based on a battery of neuropsychological tests that assessed episodic memory, semantic memory, working memory, and executive function. A series of separate linear regression models were used to evaluate associations of vascular risk scores with outcomes of cognition and serum biomarkers. All models were adjusted for age, education level, and racial and ethnic background. Results: In separate linear regression models, both ASCVD and CHA2DS2-VASc scores were inversely associated with semantic memory (β= –0.22, p = 0.007 and β= –0.15, p = 0.022, respectively), with no significant findings for the other cognitive domains. There were no significant associations between vascular risk scores and serum biomarkers. Conclusions: Future studies should prospectively examine associations between vascular risk and cognition in other populations and additionally consider other serum biomarkers that may be related to vascular risk and cognition.
Optimizing the Implementation of a Lifestyle Dementia Prevention Intervention for Older Patients in an Academic Healthcare System
Authors: Mace Ryan A. , Lyons Christopher , Cohen Joshua E. , Ritchie Christine , Bartels Stephen , Okereke Olivia I. , Hoeppner Bettina B. , Brewer Judson A. , Vranceanu Ana-Maria 
Published: July 2024

Background: Interventions that promote healthy lifestyles are critical for the prevention of Alzheimer’s disease and Alzheimer’s disease related dementias (AD/ADRD). However, knowledge of the best practices for implementing AD/ADRD prevention in healthcare settings remains limited. Objective: We aimed to qualitatively identify barriers and facilitators to implementing a clinical trial of a novel lifestyle intervention ( My Healthy Brain) in our medical center for older patients with subjective cognitive decline who are at-risk for AD/ADRD. Methods: We conducted focus groups with 26 healthcare professionals (e.g., physicians, psychology, nursing) from 5 clinics that treat older patients (e.g., memory care, psychiatry). Our qualitative analysis integrated two implementation frameworks to systematically capture barriers and facilitators to AD/ADRD prevention (Consolidated Framework for Implementation Science Research) that impact implementation outcomes of acceptability, appropriateness, and feasibility (Proctor’s framework). Results: We found widespread support for an RCT of My Healthy Brain and AD/ADRD prevention. Participants identified barriers related to patients (stigma, technological skills), providers (dismissiveness of “worried well,” doubting capacity for behavior change), clinics (limited time and resources), and the larger healthcare system (underemphasis on prevention). Implementation strategies guided by Expert Recommendations for Implementing Change (ERIC) included: developing tailored materials, training staff, obtaining buy-in from leadership, addressing stigmatized language and practices, identifying “champions,” and integrating with workflows and resources. Conclusions: The results will inform our recruitment, enrollment, and retention procedures to implement the first randomized clinical trial of My Healthy Brain. Our study provides a blueprint for addressing multi-level barriers to the implementation of AD/ADRD prevention for older patients in medical settings.
The Impact of Misaligned Perceived and Objective Fall Risk in Cognitively Impaired Older People
Authors: Taylor Morag E. , Kerckhaert Luuk , Close Jacqueline C.T. , van Schooten Kimberley S. , Lord Stephen R. 
Published: July 2024

Background: Cognitive impairment (CI) may impair the ability to accurately perceive physical capacity and fall risk. Objective: We investigated perceived (measured as concern about falls) and physiological fall risk in community-dwelling older people with CI, the characteristics of the aligned and misaligned groups and the impact of misaligned perceptions on falls. Methods: Participants ( n= 293) with mild-moderate CI were classified into four groups based on validated physiological and perceived fall risk assessments: 1) vigorous: low perceived and physiological fall risk; 2) anxious: high perceived and low physiological fall risk; 3) unaware: low perceived and high physiological fall risk; and 4) aware: high perceived and physiological fall risk. Groups were compared with respect to neuropsychological and physical function, activity and quality of life measures, and prospective falls (12-months). Results: The anxious (IRR = 1.70, 95% CI = 1.02–2.84), unaware (IRR = 2.00, 95% CI = 1.22–3.26), and aware (IRR = 2.53, 95% CI = 1.67–3.84) groups had significantly higher fall rates than the vigorous group but fall rates did not significantly differ among these groups. Compared with the vigorous group: the anxious group had higher depression scores and reduced mobility and quality of life; the unaware group had poorer global cognition, executive function and mobility and lower physical activity levels; and the aware group had an increased prevalence of multiple physical and cognitive fall risk factors. Conclusions: Fall rates were increased in participants who had increased perceived and/or physiological fall risk. Contrasting fall risk patterns were evident in those who under- and over-estimated their fall risk. Understanding these characteristics will help guide fall risk assessment and prevention strategies in community-dwelling older people with CI.
Quantitative muscle MRI in sporadic inclusion body myositis (sIBM): A prospective cohort study
Authors: Schlaffke Lara , Rehmann Robert , Froeling Martijn , Güttsches Anne-Katrin , Vorgerd Matthias , Enax-Krumova Elena , Forsting Johannes 
Published: July 2024

Background: Sporadic inclusion body myositis (sIBM) is the predominant idiopathic inflammatory myopathy (IIM) in older people. Limitations of classical clinical assessments have been discussed as possible explanations for failed clinical trials, underlining the need for more sensitive outcome measures. Quantitative muscle MRI (qMRI) is a promising candidate for evaluating and monitoring sIBM. Objective: Longitudinal assessment of qMRI in sIBM patients. Methods: We evaluated fifteen lower extremity muscles of 12 sIBM patients (5 females, mean age 69.6, BMI 27.8) and 12 healthy age- and gender-matched controls. Seven patients and matched controls underwent a follow-up evaluation after one year. Clinical assessment included testing for muscle strength with Quick Motor Function Measure (QMFM), IBM functional rating scale (IBM-FRS), and gait analysis (6-minute walking distance). 3T-MRI scans of the lower extremities were performed, including a Dixon-based sequence, T2 mapping and Diffusion Tensor Imaging. The qMRI-values fat-fraction (FF), water T2 relaxation time (wT2), fractional anisotropy (FA), mean diffusivity (MD), axial diffusivity ( λ1), and radial diffusivity (RD) were analysed. Results: Compared to healthy controls, significant differences for all qMRI parameters averaged over all muscles were found in sIBM using a MANOVA ( p < 0.001). In low-fat muscles (FF < 10%), a significant increase of wT2 and FA with an accompanying decrease of MD, λ1, and RD was observed ( p≤0.020). The highest correlation with clinical assessments was found for wT2 values in thigh muscles ( r≤–0.634). Significant changes of FF (+3.0%), wT2 (+0.6 ms), MD (–0.04 10-3mm2/s), λ1 (–0.05 10-3mm2/s), and RD (–0.03 10-3mm2/s) were observed in the longitudinal evaluation of sIBM patients ( p≤0.001). FA showed no significant change ( p = 0.242). Conclusion: qMRI metrics correlate with clinical findings and can reflect different ongoing pathophysiological mechanisms. While wT2 is an emerging marker of disease activity, the role of diffusion metrics, possibly reflecting changes in fibre size and intracellular deposits, remains subject to further investigations.
Usia Pengguna Kontrasepsi Depo Medroksi Progesteron Asetat (DMPA) Terhadap Peningkatan Berat Badan Akseptor Keluarga Berencana Di Puskesmas Pekkae Kabupaten Barru
Authors: Husain Hastuti , Nazar Putri Awalia , Marhaeni Marhaeni , Subriah Subriah 
Published: July 2024

Kontrasepsi yang paling banyak diminati dan populer di kalangan perempuan yaitu depo medroksi progesteron asetat (DMPA) karena dianggap praktis dan mudah didapatkan di tempat pelayanan kesehatan. Tujuan penelitian untuk mengetahui pengaruh usia dan peningkatan berat badan terhadap penggunaan kontrasepsi DMPA di Puskesmas Pekkae. Metode penelitian bersifat survey analitik, dengan pendekatan cross sectional. Populasi pada penelitian ini adalah semua akseptor KB Puskesmas Pekkae sebanyak 909 akseptor dan sampel akseptor yang menggunakan DMPA sebanyak 62 akseptor.Penelitian dilakukan bulan Februari-Juni 2021 menggunakan format pengumpulan data. Dianalisis secara bivariat menggunakan uji Chi-square α = 0,05.
Hasil analisisi univariat menunjukkan bahwa sebanyak 56 orang (90,3%) akseptor mengalami peningkatan berat badan dan hanya 6 orang (9,7%) akseptor yang berat badannya tidak naik.Dan berdasarkan kelompok umur dalam katagori aman secara reproduktif sebesar 59 orang (95,2%) akseptor,hanya ada 2 orang(3,2%) akseptor yang termasuk katagori risiko tinggi untuk umur kurang <20 tahun dan juga satu orang akseptor dengan katagori risiko tinggi untuk >35 tahun (1,6%). Hasil analisis bivariat menunjukkan bahwa umur (Pvalue=1,000) dan peningkatan berat badan (Pvalue= p=0,000).Kesimpulan bahwa tidak pengaruh yang signifikan umur penggunan alat kontraspesi DMPA terhadap peningkatan berat badan akseptor KB dan penggunaan alat kontrasepsi DMPA berpengaruh secara signifikan terhadap peningkatan berat badan akseptor KB. Disarankan bagi petugas kesehatan untuk pemahaman terhadap akseptor DMPA tanpa membedakan umur untuk belajar mengatur pola makan sehingga berat badan dapat terkontrol.
Kata Kunci : Berat badan, Kontrasepsi, Usia
Ilustrasi 360 Derajat Tentang Camilan Indonesia
Authors: Herlijanto Amelia Agustina , Elizur Eirene Kezia 
Published: July 2024

Memperkenalkan budaya dapat dilakukan melalui makanan. Penelitian ini berusaha membuat ilustrasi yang menarik mengenai camilan Indonesia dalam rangka mengenal budaya Indonesia kepada anak muda. Website interaktif dipilih sebagai media untuk menampilkan ilustrasi ini agar, ilustrasi dapat dinikmati secara 360 derajat. Karya ilustrasi ini akan dibuat dalam bentuk dunia 360 derajat yang diantaranya dunia camilan bertekstur empuk, lembek, renyah, dan kental. Ilustrasi dunia camilan digambar menggunakan perspektif panorama. Karya ilustrasi akan diaplikasikan pada objek 3D dengan menggunakan software bernama Unity kemudian akan dibangun atau diproyeksikan sebagai karya ilustrasi yang dapat dilihat dan diakses dalam bentuk website. Metode penelitian yang digunakan adalah Research and Development dengan pendekatan Model ADDIE (Analisis, Desain, Development, Implementasi dan Evaluasi). Berdasarkan hasil evaluasi didapatkan bahwa karya ilustrasi yang diproyeksikan pada website dapat menambahkan pengetahuan mengenai budaya Indonesia pada kategori camilan tradisional.
O ensino de habilidades socioemocionais: seu papel no sucesso escolar
Authors: Cordeiro Jose Givaldo , Cardoso Campos Alyce , Neves Ribeiro Costa Helen , Rodrigues Duarte Oliveira Alyne Luysa 
Published: July 2024

Este artigo teve como objetivo investigar a importância do desenvolvimento socioemocional no contexto educacional e sua influência no sucesso escolar na instituição de ensino Senador Melo Viana na cidade de Moeda/MG. Para isso, foram entrevistados 15 professores com experiência no ensino de habilidades socioemocionais, de modo a apresentar suas percepções sobre a aplicação dessas habilidades em sala de aula e trazer contribuições percebidas para o sucesso acadêmico e transição para a vida. Emergem como temas centrais nos resultados da pesquisa: a preparação para a vida futura, o envolvimento ativo dos pais, o reconhecimento das diferenças individuais, a integração de tecnologia e o desenvolvimento profissional contínuo. É evidenciada a necessidade prática de implementação de estratégias eficazes no ambiente escolar, destacando a crescente adoção de abordagens centradas no desenvolvimento socioemocional em escolas ao redor do mundo. Este estudo oferece contribuições valiosas para a academia, gestão educacional e sociedade, destacando a importância de abordagens integradas para o desenvolvimento socioemocional em contextos educacionais.
Palavras-Chave: Habilidades socioemocionais. Estratégias pedagógicas. Ambientes de aprendizagem. Desenvolvimento socioemocional.

Abstract: This article aimed to investigate the importance of socio-emotional development in the educational context and its influence on academic success at the Senador Melo Viana educational institution in the city of Moeda/MG. To this end, 15 teachers with experience in teaching socio-emotional skills were interviewed, in order to present their perceptions on the application of these skills in the classroom and bring perceived contributions to academic success and transition to life. Central themes emerge in the research results: preparation for future life, active parental involvement, recognition of individual differences, integration of technology and continuous professional development. The practical need to implement effective strategies in the school environment is highlighted, highlighting the growing adoption of approaches focused on socio-emotional development in schools around the world. This study offers valuable contributions to academia, educational management and society, highlighting the importance of integrated approaches to socio-emotional development in educational contexts.
Keywords: Socio-emotional skills. Pedagogical strategies. Learning environments. Socio-emotional development.