bluuebunny/crossref_metadata_2025_split huggingface dataset:
A feasibility randomized controlled trial of culturally adapted Getting Better Bite-by-Bite (Ca-GBBB) intervention for individuals with eating disorders in Pakistan
Authors: Khaliq Ayesha , Muazzam Amina , Rafique Rafia , Kiran Tayyeba , Ahmed Ameera , Suleheria Irfan , Chaudhry Nasim , Husain Nusrat 
Published: July 2024

Abstract
Background
Eating disorders (EDs) are serious mental health conditions that affect a person physically and psychologically. In the past, EDs were only recognized as a cultural phenomenon/societal by-product of the West. However, research evidence marks its presence in non-western countries also, including South Asia. This study aims to evaluate the feasibility and acceptability of a manualized psychological intervention called Getting Better Bite by Bite (GBBB) in individuals who screened positive on measures of EDs in Pakistan.

Methods
The proposed study is a feasibility randomized controlled trial (fRCT). The study will be conducted at five sites across Pakistan: Karachi, Hyderabad, Lahore, Rawalpindi, and Multan to recruit a total of 80 participants. Eligible participants will be randomized to either (1) the intervention group; in which they will receive one-to-one sessions of GBBB along with routine care or (2) the routine care group; in which they will only have access to the routine care. We have received ethics approval by the National Bioethics Committee. The study is registered at clinicaltrials.gov (NCT05724394). The study team has received permission from recruitment centers: hospitals (i.e. the psychiatry department of public and private hospitals based in these cities), fitness centers (i.e., gyms), educational institutes (i.e., colleges and universities), and community settings (i.e. community health clinics). Self-referrals from General Practitioners and community settings will be accepted. The intervention manual has been translated into Urdu and a multidisciplinary team including service users has culturally adapted the content of intervention for local context.

Discussion
This study will provide evidence on feasibility and acceptability of a culturally adapted intervention for individuals who screen positive on measures of EDs. The findings of this study will inform a fully powered Randomized Controlled Trial of the proposed intervention.
Trial Registration. The study is registered on clinicaltrials.gov (NCT05724394). Protocol version (1.0. 1st June 2022).
The relationship between competitive anxiety and athlete burnout in college athlete: the mediating roles of competence and autonomy
Authors: Yang Linjie , Zhang Zhiwen , Zhang Jinrui , Veloo Arsaythamby 
Published: July 2024

Abstract
Background
In the cognitive-affective model of athlete burnout, anxiety is a key physiological response to stress that influences the development of burnout in athletes. Despite its importance, there has been little research on the relationship between competitive anxiety and athlete burnout, particularly regarding the mediating mechanisms. This study aimed to explore the relationship between competitive anxiety and athlete burnout, with a focus on the mediating role of general need satisfaction from self-determination theory.

Methods
The current study employed a cross-sectional design involving 618 college athletes (354 females, mean age 20.57 years), comprising 303 participants in individual sports and 315 in team sports. These participants completed the Sport Anxiety Scale-2 (SAS-2), the Athlete Burnout Questionnaire (ABQ), and the Basic Psychological Need Satisfaction Scale in General (BPNSS-G) online. Subsequently, correlation, regression, and mediation analyses were conducted using SPSS and JASP to examine the relationships between the variables.

Results
Regression results indicated that somatic anxiety (beta = 0.116, t = 2.21, p = 0.028) and concentration disruption (beta = 0.259, t = 5.35, p < 0.001) in competitive anxiety were positively correlated with athlete burnout. Worry in competitive anxiety was negatively correlated with competence (beta =-0.149, t=-2.70, p = 0.007) and autonomy (beta =-0.179, t=-3.25, p = 0.001) in needs satisfaction. Additionally, the regression results found that competence (beta =-0.178, t=-3.39, p = 0.001) and Autonomy (beta =-0.208, t=-4.17, p < 0.001) were negatively associated with athlete burnout. Mediation analyses revealed significant direct effects in the relationship between somatic anxiety (Effect = 0.116, p = 0.026) along with concentration disruption (Effect = 0.259, p < 0.001) and athlete burnout. In the indirect effect, worry (Effect = 0.071, p = 0.002) as well as concentration disruption (Effect = 0.082, p < 0.001) had significant effects in relation to athlete burnout, respectively.

Conclusions
Overall, the current study found that somatic anxiety and concentration disruption in competitive anxiety are related to athlete burnout. Moreover, competence and autonomy in need satisfaction mediated the relationship between competitive anxiety (worry and concentration disruption) and athlete burnout. The findings of this study not only shed further light on the relationship between competitive anxiety and athlete burnout but also provide theoretical insights into the mediating mechanisms of this relationship.
Harnessing natural killer cells for refractory/relapsed non-Hodgkin lymphoma: biological roles, clinical trials, and future prospective
Authors: Bakhtiyaridovvombaygi Mehdi , Yazdanparast Somayeh , Kheyrandish Setare , Safdari Seyed Mehrab , Amiri Samani Fateme , Sohani Mahsa , Jaafarian Akram Sadat , Damirchiloo Fateme , Izadpanah Amirhossein , Parkhideh Sahar , Mikanik Fatemeh , Roshandel Elham , Hajifathali Abbas , Gharehbaghian Ahmad 
Published: July 2024

AbstractNon-Hodgkin lymphomas (NHLs) are heterogeneous and are among the most common hematological malignancies worldwide. Despite the advances in the treatment of patients with NHLs, relapse or resistance to treatment is anticipated in several patients. Therefore, novel therapeutic approaches are needed. Recently, natural killer (NK) cell-based immunotherapy alone or in combination with monoclonal antibodies, chimeric antigen receptors, or bispecific killer engagers have been applied in many investigations for NHL treatment. The functional defects of NK cells and the ability of cancerous cells to escape NK cell-mediated cytotoxicity within the tumor microenvironment of NHLs, as well as the beneficial results from previous studies in the context of NK cell-based immunotherapy in NHLs, direct our attention to this therapeutic strategy. This review aims to summarize clinical studies focusing on the applications of NK cells in the immunotherapy of patients with NHL.
Improving students’ problem-solving abilities through answering questions in metaverse games: taking GOXR software as an example
Authors: Weng Ting-Sheng , Lin Ting-Hsuan 
Published: July 2024

AbstractIn computer-based dialogue learning, students’ willingness to communicate and ability to interact is one of the important factors. Few studies have examined the testing of mobile metaverse teaching material systems built for interactive communication and learning courses. This study developed and designed course content for a virtual classroom, which is suitable for mobile learning on Android or iOS systems and can provide metaverse space for students to discuss homework using their mobile phones, as well as a system for online self-learning and testing. Students can participate in classes without time or space restrictions. In addition, questions related to life math knowledge and leveling up are included, such as the basic reproduction number of COVID-19, influenza, and enterovirus. There were 100 valid responses from two schools, which recognized the convenience and benefit of the virtual digital technology of the mobile self-learning system in the metaverse space as an auxiliary tool for learning, as it provides a more flexible and diversified educational learning mode. This system can be used for course teaching, after-class review, and testing to facilitate self-testing of learning results.
Methane-cycling microbial communities from Amazon floodplains and upland forests respond differently to simulated climate change scenarios
Authors: Gontijo Júlia B. , Paula Fabiana S. , Bieluczyk Wanderlei , França Aline G. , Navroski Deisi , Mandro Jéssica A. , Venturini Andressa M. , Asselta Fernanda O. , Mendes Lucas W. , Moura José M. S. , Moreira Marcelo Z. , Nüsslein Klaus , Bohannan Brendan J. M. , Bodelier Paul L. E. , Rodrigues Jorge L. Mazza , Tsai Siu M. 
Published: July 2024

AbstractSeasonal floodplains in the Amazon basin are important sources of methane (CH4), while upland forests are known for their sink capacity. Climate change effects, including shifts in rainfall patterns and rising temperatures, may alter the functionality of soil microbial communities, leading to uncertain changes in CH4 cycling dynamics. To investigate the microbial feedback under climate change scenarios, we performed a microcosm experiment using soils from two floodplains (i.e., Amazonas and Tapajós rivers) and one upland forest. We employed a two-factorial experimental design comprising flooding (with non-flooded control) and temperature (at 27 °C and 30 °C, representing a 3 °C increase) as variables. We assessed prokaryotic community dynamics over 30 days using 16S rRNA gene sequencing and qPCR. These data were integrated with chemical properties, CH4 fluxes, and isotopic values and signatures. In the floodplains, temperature changes did not significantly affect the overall microbial composition and CH4 fluxes. CH4 emissions and uptake in response to flooding and non-flooding conditions, respectively, were observed in the floodplain soils. By contrast, in the upland forest, the higher temperature caused a sink-to-source shift under flooding conditions and reduced CH4 sink capability under dry conditions. The upland soil microbial communities also changed in response to increased temperature, with a higher percentage of specialist microbes observed. Floodplains showed higher total and relative abundances of methanogenic and methanotrophic microbes compared to forest soils. Isotopic data from some flooded samples from the Amazonas river floodplain indicated CH4 oxidation metabolism. This floodplain also showed a high relative abundance of aerobic and anaerobic CH4 oxidizing Bacteria and Archaea. Taken together, our data indicate that CH4 cycle dynamics and microbial communities in Amazonian floodplain and upland forest soils may respond differently to climate change effects. We also highlight the potential role of CH4 oxidation pathways in mitigating CH4 emissions in Amazonian floodplains.
Shunt-related brain tumor, a case report presenting a rare complication and review of literature
Authors: Zohney Michael , Aziz Mohamed M , Izz-alarab Shebl , Algredly Ahmed A , Abdelwahab Abdelaleem 
Published: July 2024

Abstract
Background
Congenital hydrocephalus is a well-known neurosurgical condition in the pediatric age group. Ventriculoperitoneal shunt (VPS) placement is a standard procedure with a high incidence of complications in the first year postoperatively. We present a very rare complication, with only a few reported cases in the accessible literature, in which a tumor arises in relation to a shunt catheter.

Study design
A case report.

Case presentation
We describe a case of a VPS placement in an eleven-month-old boy who, at the age of thirteen, presented with a two-month period of convulsions caused by a cortical mass related to the shunt catheter. Surgical excision of the mass revealed atypical meningioma (WHO Grade 2).

Conclusions
The tumor may have been initiated by direct irritation of the shunt catheter or just an unfortunate simultaneous event for this child. Further analysis is needed to determine which factors could have led to such a complication and to predict its occurrence in future patients. In this case, the pathologic features, duration, and unusual radiologic findings are interesting and unique.
Exploring the use of clay pots as sustainable storage containers to improve water quality
Authors: Ibrahim Alaa K. , Said Ghada , Badr Mai M. 
Published: July 2024

Abstract
Background
Currently, tap water consumption is not highly preferred in Egypt and around the world. People prefer to consume bottled water because they believe that it is much safer and tastes better than tap water. Unfortunately, this preference can create an economic burden for many people, especially in developing countries. Clay pots can be used to provide cool, alkaline drinking water because of their porous micro-texture, which traps pollutants. This study aimed to investigate the use of clay pots to store tap water and its impact on the requirements for drinking water quality. This is done with the intent to decrease the need for bottled water as a means of offering a more sustainable and economical option.

Methods
In this study, the efficiency of clay pots as sustainable storage containers for drinking water was tested by measuring physicochemical parameters (pH, TDS, EC, turbidity, DO, ammonia, chloride, total hardness, Ca hardness, Mg hardness, chlorine, Zn, and CaCO3) and biological parameters (TPC and Legionella).

Results
After 7 days of storage, the quality of the water stored in clay pots met the standards set by the Egyptian law with a significant difference (p < 0.05) before and after the storage of water It was found that the dissolved oxygen increased from 6.17 ppm to 7.52 ppm after 7 days. As for total hardness, it declined from 195 to 178 ppm. There was also a significant drop in terms of TDS from 338 to 275 ppm. Furthermore, clay pots effectively filtered out both total viable bacteria and Legionella.

Conclusion
This study proved the efficiency of using these containers with respect to some indicator values for tap water and tank water analysis. Clay pots are an excellent, cost-effective, and sustainable alternative for storing water.
Understanding the multilevel factors influencing the implementation of digital health interventions for supportive care in Adolescents and Young Adult (AYA) cancer survivorship: determinants of adopting mindfulness-based mobile applications
Authors: Kwok Gary , Senger Angela , Sharma Archana , Mandato Ivelisse , Devine Katie A. 
Published: July 2024

Abstract
Background
Adolescents and Young Adult (AYA) cancer survivors are at risk for psychological distress due to their unique developmental and medical needs. Healthcare providers can leverage the convenience and appeal of technology to provide supportive care for this vulnerable population. Using evidence-based mindfulness-based mobile interventions as a case example, the goal of this study was to identify key patient-, provider-, and organization-level barriers and facilitators to supportive care and implementing digital health interventions in AYA survivorship care.

Methods
Twenty semi-structured interviews were conducted with stakeholders including AYA survivors (n = 10; between 18–29 years old) and clinical providers and administrators (n = 10). Interviews were transcribed and deductively mapped using the Consolidated Framework for Implementation Research (CFIR) and Theoretical Domains Framework (TDF) complementary frameworks.

Results
Results indicated that factors like cost and patients’ needs and resources were prevalent among both survivors and providers. There were key differences between providers and AYA survivors. Providers’ adoption and promotion of digital health interventions were influenced most strongly by contextual factors, including available resources (Inner Setting), culture (Outer Setting), and networks and communications (Outer Setting). On the other hand, survivors emphasized individual and intervention-related factors; they reported that social influence and knowledge influenced their adoption and use of digital health interventions, including meditation apps.

Conclusions
These results identified barriers and facilitators to the adoption of supportive care digital health interventions from multiple stakeholders. Results can be used to guide the development of implementation strategies to improve the uptake of digital health interventions in survivorship care, ultimately improving the psychosocial well-being of AYA cancer survivors.
Challenges in understanding inequities in help-seeking for possible cancer symptoms
Authors: Whitaker Katriina L. , Perchyk Tetyana , Kerrison Robert S. , Lemanska Agnieszka 
Published: July 2024

AbstractTackling inequities in cancer outcomes is a global health priority. One avenue for improving early diagnosis of cancer is to ensure people know when and how to seek help for cancer symptoms and that this knowledge (and behaviour) is equitably distributed across the population. In this perspective piece we highlight the challenges in understanding sociodemographic differences in help-seeking behaviour (for example, how help-seeking is defined / conceptualised and subsequently assessed), as well as challenges with using existing datasets that are now more readily accessible than ever. Addressing these will strengthen methodological approaches to understand inequities in help-seeking and ways to tackle them.
The Cerebral Aqueduct Compliance: A Simple Morphometric Model
Authors: Longatti Pierluigi , Gioffrè Giorgio , Fiorindi Alessandro , Siddi Francesca , Boaro Alessandro , Basaldella Luca , Sala Francesco , Feletti Alberto 
Published: July 2024

BACKGROUND AND OBJECTIVES:
This work aimed to identify different configurations of the adytum of the cerebral aqueduct suggesting its safe neuroendoscopic navigation. This concept is intimately connected to the physiological aqueductal dilatability or compliance, which is relatively ignored in the literature. A better knowledge of the extent of physiological aqueductal dilatability might better define the ideal diameter and safer features of dedicated flexible endoscopes.

METHODS:
The study includes 45 patients operated on using a flexible scope with a 3.9-mm diameter, where the structural elements of the adytum of the cerebral aqueduct are clearly visible. Patients were grouped according to the pathology (colloid cyst/normal anatomy, intraventricular hemorrhage, tetraventricular obstructive hydrocephalus, normal pressure hydrocephalus, and distal membranous aqueductal stenosis). A simple geometrical scheme was applied to the endoscopic anatomy of the aqueductal adytum in relation to the posterior commissure to measure its pathologic deformations. Eventual damages to the aqueduct walls caused by the endoscope were also reported.

RESULTS:
Proceeding from normal anatomy to hydrocephalic condition, the ratio between the commissure and the aqueductal access area progressively decreases, while the vertex angle increases. Interestingly, the entity of the ependymal damages due to the passage of the endoscope correlates with such measures.

CONCLUSION:
The cerebral aqueduct, excluding atrophic processes, is provided with a certain degree of dilatability, which we estimate to be around a diameter of 4 mm. This represents the maximum size for a flexible neuroendoscope for a safe aqueductal neuronavigation. The schematic model of the aqueductal adytum as a triangle defines 3 different aqueductal patterns and can be helpful when an intraoperative decision on whether to navigate the aqueduct must be taken.
Editorial
Authors: ΣΙΑΚΑΣ Σπύρος , Σοφός Αλιβίζος (Λοΐζος) , Τριβέλλα Λαμπρινή 
Published: July 2024

Το παρόν τεύχος φιλοξενεί άρθρα που καλύπτουν θέματα τόσο σε θεωρητικό όσο και σε πρακτικό επίπεδο δημιουργίας βίντεο, animation και διαδραστικών μέσων στο πλαίσιο της εκπαίδευσης και του πολιτισμού. Η επιλογή των άρθρων ενισχύει το εύρος πρακτικής εφαρμογής κυρίως στην εκπαίδευση, αναδεικνύοντας και τις θεωρητικές βάσεις των διαδραστικών μέσων σε πολιτισμικό επίπεδο. Αξίζει να σημειωθεί ότι σε αυτό το τεύχος φιλοξενείται ένα άρθρο μέσα από το οποίο προσεγγίζεται η εκπαιδευτική χρήση του video modeling σε παιδιά με διαταραχή αυτιστικού φάσματος.
Performance characterization of an Al2O3/HfO2 parabolic multilayer based on a laboratory X-ray source
Authors: Yuan Tianyu , Li Yanli , Sun Tianxi , Sun Xuepeng , Niu Geng , Hu Jinyue , Hua Lu , Shao Shangkun , Zhong Yuchuan 
Published: July 2024

Parabolic multilayers (PMs) are widely used in synchrotron radiation, X-ray free electron lasers, laboratory X-ray sources, and so on, and therefore, how to expediently and effectively determine their performance is important for the designers, manufacturers, and users of them. This paper designed a method based on a laboratory X-ray source and polycapillary parallel X-ray lens to characterize the performances of one Al2O3/HfO2 PM. The results showed that a monochromatic X-ray beam with a width of 97.76 µm and a divergence of 0.667 mrad at Cu-K
α
(8.04 keV) was obtained with the PMs used in the paper based on a laboratory X-ray source with a focus size of 50–100 µm at various working powers, and its X-ray reflectivity for Cu-K
α
and Cu-K
β
was 43.71% and 38.62%, respectively.
Broadband and low-loss power splitter with polarization manipulation using subwavelength gratings
Authors: Lu Mengjia , Guo Zhenzhao , Deng Chunyu , Hu Xuefang , Chen Mengmeng 
Published: July 2024

A broadband and low-loss power splitter with polarization manipulation using subwavelength gratings (SWGs) is proposed and analyzed, where SWGs are embedded in input taper/output inverse tapered waveguides in the bottom layer to form an SWG-based structure, and a silicon nitride layer is placed above the bottom layer to form a low-index guiding structure. In the bottom layer, the TE mode is cut off as the input strip waveguide is tapered down. In this way, the injected TE mode is evenly coupled to two adjacent output ports with high efficiency by the assistance of SWGs. By contrast, the input TM mode is well supported by the above silicon nitride layer and directly transmitted to the Through port, which is almost not influenced by the bottom structures. Consequently, both power splitting and polarization handling are achieved in the designed device simultaneously. Simulation results show that an extinction ratio (ER) of 32.63 dB (18.56 dB) and insertion loss (IL) of 0.16 dB (0.16 dB) for the TE (TM) mode are obtained at 1.55 µm. The bandwidth is up to 191 nm (1450–1641 nm) for the TE mode and 200 nm (1450–1650 nm) for the TM mode with an ER exceeding 15 dB and IL below 0.3 dB. Furthermore, fabrication tolerances and power distribution with polarization manipulation through the device are also presented.