bluuebunny/crossref_metadata_2025_split huggingface dataset:
Monitoring Osteoarthritis: A Cross-sectional Survey in General Practice
Authors: Clarson Lorna E. , Nicholl Barbara I. , Bishop Annette , Edwards John J. , Daniel Rebecca , Mallen Christian D. 
Published: November 2013

Background Despite being a highly prevalent chronic condition managed predominantly in primary care and unlike other chronic conditions, osteoarthritis (OA) care is delivered on an ad hoc basis rather than through routine structured review. Evidence suggests current levels of OA care are suboptimal, but little is known about what general practitioners’ (GPs) consider important in OA care, and, thus, the scope to improve inconsistency or poor practice is, at present, limited. Objectives We investigated GPs’ views on and practice of monitoring OA. Methods This was a cross-sectional postal survey of 2500 practicing UK GPs randomly selected from the Binley's database. Respondents were asked if monitoring OA patients was important and how monitoring should be undertaken. Results Responses were received from 768 GPs of whom 70.8% were male and 89.5% were principals within their practices. Despite 55.4% (n = 405) indicating monitoring patients with OA was important and 78.3% (n = 596) considering GPs the appropriate professionals to monitor OA, only 15.2% (n = 114) did so routinely, and 45% (n= 337) did not monitor any OA patients at all. In total, 61.4% (n = 463) reported that patients should self-monitor. Respondents favored monitoring physical function, pain, and analgesia use over monitoring measures of BMI, self management plans, and exercise advice. Conclusions The majority of respondents felt that monitoring OA was important, but this was not reflected in their reported current practice. Much of what they favored for monitoring was in line with published guidance, suggesting provision of suboptimal care does not result from lack of knowledge and interventions to improve OA care must address barriers to GPs engaging in optimal care provision.
Sustained Elevation of Kynurenic Acid in the Cerebrospinal Fluid of Patients with Herpes Simplex Virus Type 1 Encephalitis
Authors: Atlas Ann , Franzen-Röhl Elisabeth , Söderlund Johan , Jönsson Erik G , Samuelsson Martin , Schwieler Lilly , Sköldenberg Birgit , Engberg Göran 
Published: November 2013

Herpes simplex virus (HSV) type 1 encephalitis (HSE) is a viral infectious disease with commonly occurring neurodegeneration and neurological/cognitive long-term sequelae. Kynurenic acid (KYNA) is a neuroactive tryptophan metabolite, which is elevated in the cerebrospinal fluid (CSF) during viral infection as a result of immune activation. The aim of the study was to investigate the role of endogenous brain KYNA for the long-term outcome of the disease. CSF KYNA concentration was analyzed in 25 HSE patients along the course of the disease and compared with that of 25 age-matched healthy volunteers. Within 3 weeks of admission CSF KYNA of HSE patients was markedly elevated (median 33.6 nM) compared to healthy volunteers (median 1.45 nM). Following a decline observed after 1–2 months, levels of CSF KYNA were elevated more than 1 year after admission (median 3.4 nM range: 1–9 years). A negative correlation was found between initial CSF KYNA concentrations and severity of the long-term sequelae. This study show a marked elevation in CSF KYNA from patients with HSE, most pronounced during the acute phase of the disease and slowly declining along the recovery. We propose that brain KYNA might potentially protect against neurodegeneration while causing a long-lasting loss in cognitive function associated with the disease.
Rehabilitation of a Completely Edentulous Patient using TENS to record Functional Borders and Cheek Plumpers for Esthetics
Authors: Kulkarni Shilpa , Bulbule Nilesh Shrikant , Shah Jay , Kakade Dilip 
Published: November 2013

ABSTRACT
The facial disfigurement associated with the loss of teeth has greater psychological effect on the patient than the actual loss of teeth. Presented herein, is a novel, precise and accurate technique of performing border molding using transcutaneous electric nerve stimulation (TENS). The electronic stimulator is programed to deliver precisely controlled, uniform stimuli transmitted by transcutaneous electrical neural stimulation through fifth and seventh cranial nerves.
Plumping the cheeks by using cheek plumpers attached to the conventional complete denture using magnets was also done. The greatest advantage lies in the fact that they are completely detachable.

How to cite this article
Bulbule NS, Shah J, Kulkarni S, Kakade D. Rehabilitation of a Completely Edentulous Patient using TENS to record Functional Borders and Cheek Plumpers for Esthetics. Int J Prosthodont Restor Dent 2013;3(2):78-82.
Management of Edentulous Resorbed Mandibular Residual Ridge in Malaysian Geriatric Patients: 2-Year Clinical Study
Authors: Mustafa Ammar A 
Published: November 2013

ABSTRACT

Objectives
A combination of the neutral zone and the polished surface impression techniques is a useful method to reserve the functional and physiological forms of the underlying mandibular residual ridge by enhancing both retention and stability in Malaysian geriatric patients (2-year clinical study).

Materials and methods
A total of 25 Malaysian geriatric patients have participated in the current study. Two sets of dentures were served to the patients. The first set was constructed according the conventional method of complete denture construction whereas the second set was constructed by using neutral zone and polished surface impression techniques.

Results
The patients were followed up for 2 years and the obtained results showed that all patients have stopped using the conventional dentures and continued with the test dentures. The comparative analysis exhibited significant difference (p < 0.05) in favor of test dentures.

Conclusion
Combination of the neutral zone and the polished surface techniques can impart a physiological reservation to the underlying residual ridge without changes.

Statement of problem
It is common for completely edentulous geriatric patients to have resorbed mandibular residual ridge because of the process of aging. Some surgical interactions are contraindicated for this age group of patients, so, neutral zone technique and/or polished surface impression verified effective in improving stability for lower complete dentures. In spite of the fact that the above mentioned methods often used to enhance stability of complete denture, most of the studies were relying on only one of those methods to improve stability rather than retention. Researcher hypothesis stated that a combination of the neutral zone and the polished surface impression techniques should be performed together to enhance both stability and retention and henceforth reservation of the residual ridge under mandibular complete dentures issued to the patients with a constant follow-up for two consecutive years.

How to cite this article
Mustafa AA. Management of Edentulous Resorbed Mandibular Residual Ridge in Malaysian Geriatric Patients: 2-Year Clinical Study. Int J Prosthodont Restor Dent 2013;3(2):83-86.
Heritability of face shape in twins: a preliminary study using 3D stereophotogrammetry and geometric morphometrics
Authors: Weinberg Seth M. , Parsons Trish E. , Marazita Mary L. , Maher Brion S. 
Published: November 2013

Introduction: Previous research suggests that aspects of facial surface morphology are heritable. Traditionally, heritability studies have used a limited set of linear distances to quantify facial morphology and often employ statistical methods poorly designed to deal with biological shape. In this preliminary report, we use a combination of 3D photogrammetry and landmark-based morphometrics to explore which aspects of face shape show the strongest evidence of heritability in a sample of twins. Methods: 3D surface images were obtained from 21 twin pairs (10 monozygotic, 11 same-sex dizygotic). Thirteen 3D landmarks were collected from each facial surface and their coordinates subjected to geometric morphometric analysis. This involved superimposing the individual landmark configurations and then subjecting the resulting shape coordinates to a principal components analysis. The resulting PC scores were then used to calculate rough narrow-sense heritability estimates. Results: Three principal components displayed evidence of moderate to high heritability and were associated with variation in the breadth of orbital and nasal structures, upper lip height and projection, and the vertical and forward projection of the root of the nose due to variation in the position of nasion. Conclusions: Aspects of facial shape, primarily related to variation in length and breadth of central midfacial structures, were shown to demonstrate evidence of strong heritability. An improved understanding of which facial features are under strong genetic control is an important step in the identification of specific genes that underlie normal facial variation.
L’étude des identités dans l’Antiquité est-elle utopique ?
Authors: Bélanger Steeve 
Published: November 2013

Au cours des dernières décennies, la recherche en histoire ancienne a connu un important renouvellement historiographique, méthodologique et thématique ayant permis d’aborder sous des angles novateurs d’importants acquis et présupposés de la recherche et de leur apporter de riches nuances. Les multiples enquêtes sur les constructions, déconstructions et reconstructions des identités anciennes ont grandement contribué à ce renouvellement de la recherche. Loin d’être utopiques et anachroniques, les recherches sur les phénomènes identitaires dans l’Antiquité ouvrent sur des perspectives nouvelles qu’il convient désormais de prendre en considération en histoire ancienne.
Peer Review Guidance: How Do You Write a Good Review?
Authors: Allen Thomas Wesley 
Published: November 2013

Abstract
Peer review is essential to the quality of scientific publications. As the volume of submissions to these journals increases, the need for an expanding cadre of trained reviewers also increases. Many reviewers do not receive formal training on conducting a peer review or education on the peer review process, however. The author presents an overview of the peer review process and provides guidance for conducting high-quality reviews of manuscripts submitted to The Journal of the American Osteopathic Association and other scientific journals.
Third‐Trimester Abnormal Uterine Artery Doppler Findings Are Associated With Adverse Pregnancy Outcomes
Authors: Shwarzman Polina , Waintraub Adi Y. , Frieger Michael , Bashiri Asher , Mazor Moshe , Hershkovitz Reli 
Published: November 2013

ObjectivesTo evaluate the association between third‐trimester abnormal uterine artery Doppler findings and pregnancy outcomes.MethodsA prospective study was designed, including 198 consecutive singleton pregnancies between 27 and 41 weeks' gestation. In the study population, 144 had normal uterine artery Doppler waveforms, 37 had unilateral pathologic waveforms, and 17 had bilateral pathologic waveforms. Eighty patients had intrauterine growth restriction (IUGR), preeclampsia toxemia, or both, and 118 had no complications and served as a control group. The uterine artery Doppler waveform was considered abnormal when a notch or pulsatility index above the 90th percentile was noted.ResultsIn patients with bilateral pathologic uterine artery Doppler waveforms, the rates of cesarean delivery, small‐for‐gestational‐age (SGA) neonates, preterm delivery, and low Apgar scores were increased compared to patients with normal or pathologic unilateral waveforms (P = .009; P > .001; P = .007; P > .001, respectively). The incidence rates for SGA neonates, cesarean delivery, and preterm delivery were significantly higher among patients without IUGR or preeclampsia toxemia when associated with pathologic bilateral waveforms in comparison to normal waveforms (P = .01 for all). A bilateral pathologic waveform was found to be an independent risk factor for cesarean delivery and SGA neonates. The incidence rates for SGA neonates and preterm delivery were significantly higher among patients with IUGR and/or preeclampsia toxemia when associated with bilateral abnormalities in comparison to normal waveforms (P = .01 for both).ConclusionsThird‐trimester abnormal uterine artery Doppler findings are associated with worse perinatal outcomes among patients both with and without pregnancy complications.
Twin Reversed Arterial Perfusion Sequence
Authors: Oliver Edward R. , Coleman Beverly G. , Goff Donna A. , Horii Steven C. , Howell Lori J. , Rychik Jack , Bebbington Michael W. , Johnson Mark P. 
Published: November 2013

ObjectivesThe purpose of this study was to test the hypothesis that using the formula of a prolate ellipsoid to estimate parabiotic twin mass correlates better with findings of pump twin compromise than using the sonographic method of Moore et al (Am J Obstet Gynecol 1990; 163:907–912).MethodsA 10‐year retrospective review was performed to identify all cases of the suspected twin reversed arterial perfusion (TRAP) sequence. Parabiotic twin mass was estimated by summing body and extremity volumes calculated using the prolate ellipsoid formula (width × height × length × 0.523). Parabiotic twin mass was also estimated using the sonographic Moore method [1.21 × length2 − (1.66 × length)]. Parabiotic twin mass estimated by both methods was correlated with sonographic findings associated with increased risk of pump twin compromise.ResultsFifty‐nine pregnancies complicated by TRAP were identified. Using the prolate ellipsoid formula, the parabiotic twin mean sizes ± SD (as a percentage of pump twin weight) were 103.0% ± 52.0% and 56.9% ± 44.3% in cases with and without pump twin compromise (P = .0005), respectively. Using the sonographic Moore method, the mean parabiotic twin sizes were 122.9% ± 54.3% and 99.6% ± 62.8% in cases with and without pump twin compromise (P = .14). The median estimated masses of the parabiotic twin were 197 ± 219 g using the prolate ellipsoid formula and 310 ± 212 g using the sonographic Moore method (P = .0001). A parabiotic twin size greater than 70% of the pump twin correlated with findings associated with increased risk of pump twin compromise when using the prolate ellipsoid formula (P = .002) but not the sonographic Moore method (P = .09).ConclusionsSonographic findings associated with increased risk of pump twin compromise correlate better with prolate ellipsoid estimates of parabiotic twin mass. The median estimated mass of the parabiotic twin was statistically larger when calculated by the sonographic Moore method than by the prolate ellipsoid formula.
Low Nondiagnostic Rate for Fine‐Needle Capillary Sampling Biopsy of Thyroid Nodules
Authors: Mahony Gregory T. , Mahony Barry S. 
Published: November 2013

ObjectivesThis study examined the hypothesis that sonographically guided fine‐needle capillary thyroid biopsies performed by an experienced operator and with constant technique on nodules that meet the Society of Radiologists in Ultrasound criteria warranting biopsy can result in a nondiagnostic rate that is significantly lower than prior published reports.MethodsWe retrospectively reviewed the sonographic and pathologic reports from 228 consecutive sonographically guided fine‐needle capillary thyroid biopsies performed during a 3‐year interval by a single operator with more than 15 years of experience performing fine‐needle capillary thyroid biopsies. There were no exclusion criteria. Sonographic and pathologic reports from all nodules biopsied were included in the analysis. The radiologist's protocol included 6 fine‐needle capillary biopsies, each with 20 passes of the needle into the periphery and/or solid components of the nodule. The cytologic specimens were reviewed off‐site in adherence with the Bethesda system for reporting thyroid cytopathologic findings and classified as diagnostic or nondiagnostic. The nondiagnostic rate in this study was compared with the nondiagnostic rates in prior published reports.ResultsAmong the 228 fine‐needle capillary thyroid biopsies performed during the study interval, cytologic analysis showed 1 nondiagnostic biopsy, yielding a nondiagnostic rate of 0.4%. This rate was significantly lower than previously published reports (P < .001).ConclusionsSonographically guided fine‐needle capillary biopsies of the thyroid performed by an experienced radiologist can result in a nondiagnostic rate of less than 1%. This finding warrants further investigation into the reasons for the discrepancy between the results of this study and other previous reports.
On fitting a triangle into a circle: A study on employment outcomes of adults with Fetal Alcohol Spectrum Disorder who attended postsecondary institutions
Authors: Duquette Cheryll , Orders Shari 
Published: November 2013

Duquette, C., & Orders, S. (2013). On fitting a triangle into a circle: A study on employment outcomes of adults with Fetal Alcohol Spectrum Disorder who attended postsecondary institutions. The International Journal Of Alcohol And Drug Research, 2(3), 27-36. doi:10.7895/ijadr.v2i3.105 (http://dx.doi.org/10.7895/ijadr.v2i3.105)Aim: This study examined the employment outcomes of individuals with FASD who had undertaken postsecondary studies.Design: A qualitative research design using inductive thematic analysis and descriptive statistics was employed.Setting: The study took place in the United States and Canada.Participants: Ten adoptive mothers, one birth mother, one step-mother and one mother-in-law (N=13), representing 17 adult children, responded to the survey. Four adults with FASD who had undertaken postsecondary studies each participated in an individual interview.Measures: An electronic survey consisting mostly of open-ended items was used to obtain data on the postsecondary and employment experiences of adults with FASD from the perspectives of their relatives. Adults with FASD participated in individual interviews in which they elaborated on their experiences.Findings: More than half of the adults with FASD were employed, albeit mostly in the service sector and on a part-time basis. Four of the adults had received an early diagnosis, and these individuals were all employed; two were working in the area of their postsecondary studies. Six of the adults with FASD who had completed their college programs were working at the time of the research.Conclusions: For those individuals who did not graduate or were not employed, symptoms of FASD and other disabilities (e.g., substance abuse and mental health problems) were related to these negative outcomes. However, a supportive network of friends and family contributed to success in postsecondary studies and employment.
Summer melt regulates winter glacier flow speeds throughout Alaska
Authors: Burgess Evan W. , Larsen Christopher F. , Forster Richard R. 
Published: November 2013

AbstractPredicting how climate change will affect glacier and ice sheet flow speeds remains a large hurdle toward accurate sea level rise forecasting. Increases in surface melt rates are known to accelerate glacier flow in summer, whereas in winter, flow speeds are believed to be relatively invariant. Here we show that wintertime flow speeds on nearly all major glaciers throughout Alaska are not only variable but are inversely related to melt from preceding summers. For each additional meter of summertime melt, we observe an 11% decrease in wintertime velocity on glaciers of all sizes, geometries, climates, and bed types. This dynamic occurs because interannual differences in summertime melt affect how much water is retained in the subglacial system during winter. The ubiquity of the dynamic indicates it occurs globally on glaciers and ice sheets not frozen to their beds and thus constitutes a new mechanism affecting sea level rise projections.
Greenland subglacial lakes detected by radar
Authors: Palmer Steven J. , Dowdeswell Julian A. , Christoffersen Poul , Young Duncan A. , Blankenship Donald D. , Greenbaum Jamin S. , Benham Toby , Bamber Jonathan , Siegert Martin J. 
Published: November 2013

AbstractSubglacial lakes are an established and important component of the basal hydrological system of the Antarctic ice sheets, but none have been reported from Greenland. Here we present airborne radio echo sounder (RES) measurements that provide the first clear evidence for the existence of subglacial lakes in Greenland. Two lakes, with areas ~8 and ~10 km2, are found in the northwest sector of the ice sheet, ~40 km from the ice margin, and below 757 and 809 m of ice, respectively. The setting of the Greenland lakes differs from those of Antarctic subglacial lakes, being beneath relatively thin and cold ice, pointing to a fundamental difference in their nature and genesis. Possibilities that the lakes consist of either ancient saline water in a closed system or are part of a fresh, modern open hydrological system are discussed, with the latter interpretation considered more likely.
The effect of geomagnetic‐storm‐induced enhancements to ionospheric emissions on the interpretation of the TIMED/GUVI O/N2 ratio
Authors: Lee Woo Kyoung , Kil Hyosub , Paxton Larry J. , Zhang Yongliang , Shim Ja Soon 
Published: November 2013

AbstractWe examine the consequence of enhanced atomic oxygen (OI) 135.6 nm emissions due to the recombination of O+ with electrons on the column number density ratio of atomic oxygen to molecular nitrogen (O/N2 ratio) provided by Global Ultraviolet Imager (GUVI) on board the Thermosphere, Ionosphere, Mesosphere Energetics and Dynamics satellite. GUVI O/N2 ratio is derived from the measurements of OI 135.6 nm and N2 Lyman‐Birge‐Hopfield airglow emissions. The OI 135.6 nm emission arises from two sources: photoelectron impact excitation of neutral atomic oxygen and the radiative recombination of O+ with electrons. We estimate the O/N2 ratio disturbance associated with the O+ density enhancement during geomagnetic storms through the case study of the storms on 20 November 2003 and 8 November 2004. The OI 135.6 nm emission enhancement originating from the ionosphere is derived using the Utah State University Global Assimilation of Ionospheric Measurements model ionosphere. Our results show that the O/N2 ratio increase from the equator to middle latitudes during the storm periods is primarily associated with thermospheric neutral composition disturbances. However, the contribution of the OI 135.6 nm emission originating from the ionosphere to the storm time O/N2 ratio increase is substantial in the northern low‐middle latitude regions where severe plasma density enhancements occur during the main phase of the storms. Therefore, the ionospheric contribution should be considered for an accurate assessment of the storm time O/N2 ratio increase at low‐middle latitudes during these large storm events.