bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pointing Forward: Typing for Academic Access
Authors: Ashby Christine , Kasa Christi 
Published: October 2013

AbstractFor students who do not demonstrate reliable verbal speech, utilization of augmentative and alternative communication, both low-tech and high-tech, can be an effective way of engaging meaningfully in the academic and social opportunities of the classroom. This article discusses the benefits of drawing on a variety of communication supports, including typing to communicate, and outlines key principles and practices for the successful inclusion of students who type in academic classes. Key principles include universal design, presuming competence, writing effective IEP goals, and successful classroom strategies.
Neuronal activity regulates astrocytic Nrf2 signaling
Authors: Habas Agata , Hahn Junghyun , Wang Xianhong , Margeta Marta 
Published: October 2013

Significance
Tripartite synapse, which consists of presynaptic neuron, postsynaptic neuron, and perisynaptic astrocyte, is the central site of intercellular communication in the brain. Here, we show that neuron–astrocyte signaling at the tripartite synapse also regulates activity of nuclear factor erythroid 2-related factor 2 (Nrf2), the transcriptional master regulator of the stress-induced cytoprotective response: through secretion of neurotransmitter glutamate and other soluble messengers, elevated neuronal activity leads to increased expression of Nrf2-regulated genes in neighboring astrocytes. By optimizing astrocyte neuroprotective capacity to the level of adjacent synaptic activity, this regulatory mechanism may contribute to the maintenance of brain health under physiological stress.
Cyclic 100-ka (glacial-interglacial) migration of subseafloor redox zonation on the Peruvian shelf
Authors: Contreras Sergio , Meister Patrick , Liu Bo , Prieto-Mollar Xavier , Hinrichs Kai-Uwe , Khalili Arzhang , Ferdelman Timothy G. , Kuypers Marcel M. M. , Jørgensen Bo Barker 
Published: October 2013

Significance
Microbial life beneath the seafloor affects global-scale biogeochemical processes in the ocean, including the carbon and nutrient cycles. Although considered a stable ecosystem, dynamic interaction of this deep biosphere with climate and ocean chemistry remains poorly understood. We used high-resolution geochemical tools to study the sediment archive of the Peru continental shelf and discovered signatures of past changes in subseafloor microbial oxidation of methane. A transient reaction-transport model was used to reconstruct upward and downward migrations of the methane oxidation front according to 100-ka cyclic variations in sediment deposition. The results show for the first time how microbial life beneath the seafloor interacts with changing climate and oceanographic conditions on a glacial-interglacial time scale.
Plus-end tracking proteins, CLASPs, and a viral Akt mimic regulate herpesvirus-induced stable microtubule formation and virus spread
Authors: Naghavi Mojgan H. , Gundersen Gregg G. , Walsh Derek 
Published: October 2013

Significance
Viruses exploit their host’s microtubule (MT) transport system to move within infected cells at various stages of their life cycle. The formation and stability of MT networks is controlled by specialized host proteins, which track MT ends. These proteins, called “+TIPs” (plus-end tracking proteins), stabilize subsets of MTs in response to various environmental signals. How viruses influence the organization of these critical intracellular transport networks to facilitate infection remains poorly understood. In this study, we demonstrate that herpes simplex virus type 1 (HSV-1), which infects an estimated 60–90% of the world’s population, encodes a kinase that targets specific +TIPs to stabilize MTs formed at the trans-Golgi network, an alternate MT organizing center and organelle central to viral envelopment, to facilitate HSV-1 spread.
Neonicotinoid clothianidin adversely affects insect immunity and promotes replication of a viral pathogen in honey bees
Authors: Di Prisco Gennaro , Cavaliere Valeria , Annoscia Desiderato , Varricchio Paola , Caprio Emilio , Nazzi Francesco , Gargiulo Giuseppe , Pennacchio Francesco 
Published: October 2013

Significance
Honey bees are exposed to a wealth of synergistically interacting stress factors, which may induce colony losses often associated with high infection levels of pathogens. Neonicotinoid insecticides have been reported to enhance the impact of pathogens, but the underlying immune alteration is still obscure. In this study we describe the molecular mechanism through which clothianidin adversely affects the insect immune response and promotes replication of a viral pathogen in honey bees bearing covert infections. Our results shed light on a further level of regulation of the immune response in insects and have implications for bee conservation.
Nitrite produced byMycobacterium tuberculosisin human macrophages in physiologic oxygen impacts bacterial ATP consumption and gene expression
Authors: Cunningham-Bussel Amy , Zhang Tuo , Nathan Carl F. 
Published: October 2013

SignificanceMost people infected withMycobacterium tuberculosis(Mtb) suppress the pathogen’s replication without eradicating it. It is unknown how Mtb survives for decades in a hostile host environment. Respiration of nitrate to nitrite could help Mtb survive in hypoxic tissues but was not thought to be significant at physiologic oxygen tensions, nor was the resultant nitrite considered consequential to Mtb’s physiology. We found that Mtb infecting human macrophages in vitro produces copious nitrite at physiologic oxygen tensions. This slows Mtb’s growth and consumption of ATP and remodels its transcriptome differently than nitric oxide. Thus, respiration of nitrate and adaptation to nitrite are likely to play a prominent role in Mtb’s pathophysiology, whether or not the Mtb resides in hypoxic sites.
Experimental investigation on the surface humidity of fabric during the process of dynamic moisture liberation
Authors: Li Wenbin , Jiang Peiqing , Wang Xin , Li GaoWen , Xu Weilin 
Published: October 2013

Purpose
– In this study, a novel dynamic testing method was established to measure the moisture variation of fabric surface during the process of moisture liberation in simulated windy condition. The paper aims to discuss these issues

Design/methodology/approach
– In this method, the samples were rotating during the test process so as to simulate the external windy environment. Effects of simulated wind speed, moisture regains and fabric materials on the surface moisture of fabric were investigated.

Findings
– Experimental results showed that the surface moisture presented a trapezoidal moisture liberation curve, it increased at first, then kept stable for a while, and decreased finally with the increase of time. It took longer time for the fabric to complete the liberation process when the moisture regain of the fabric increased or the simulated wind speed decreased. The fiber materials of the fabric affected the time for the moisture liberation process under a specific windy condition.

Practical implications
– This study will benefit the designing and development of clothing such as sportswear.

Originality/value
– A dynamic testing method was proposed to characterize the surface humidity of textiles under simulated windy conditions.
Science park or innovation cluster?
Authors: Salvador Elisa , Mariotti Ilaria , Conicella Fabrizio 
Published: October 2013

Purpose– The purpose of this paper is to focus on the science park (SP) “physical” location and the innovation cluster (IC) “virtual” location, and aims at investigating: the motivations driving firms to settle in these two agglomerations; the main problems firms, belonging to the two structures, face in their growth process; similarities and differences between a “physical” and a “virtual” location; which forms of proximity (geographical, relational, social, cognitive, organizational, and institutional) play a role within the SP and the IC.Design/methodology/approach– A literature review on proximity is followed by an investigation of the Bioindustry Park and the IC BioPmed in Piedmont region in Italy, through a structured questionnaire, sent between February and March 2002, to firms co-located in the park and/or member of the cluster.Findings– From the analysis did emerge that the physical location in the park and the virtual location in the cluster might be complements rather than substitutes.Research limitations/implications– Shortcomings like the limited number of companies interviewed, and the absence of a sample of companies exclusively co-located in the park, are observable. Additional research might corroborate the results, which are specifically valid for the two case studies.Practical implications– The idea of understanding differences and similarities between the SP and the IC, and of investigating which proximity typologies play a role in a “physical” and in a “virtual” location, may be useful to design future policy strategies.Originality/value– The originality of this paper is given by the analysis of a new phenomenon: physical and virtual agglomeration typologies, characterized by several forms of proximity enhancing knowledge diffusion.
Exploring business growth and eco innovation in rural small firms
Authors: Martin Lynn , McNeill Tamara , Warren-Smith Izzy 
Published: October 2013

Purpose
– The purpose of this paper is to explore eco innovation in rural small firms. It looks at the motivations of rural small business owners for eco innovation and the extent to which rurality is important. Owner-managers’ perceptions of how eco innovation had, or would, contributed to growth in the future are also explored.

Design/methodology/approach
– This is a qualitative study involving micro-level exploration of eight growth-oriented rural small firms and their implementation of eco innovation. These case studies involved semi-structured interviews, observation of practices in the firm and review of documentation and web-based materials.

Findings
– Within each of the case study businesses, eco innovation involved changing business processes to reduce waste and to reduce the amounts of raw materials consumed. Rurality was described as very important due to closeness to the impacts of climate change and firms’ visibility within their local communities. Although none of the businesses identified growth as a motivating factor, each enjoyed economic benefits as a result of their pro-environmental behaviour.

Research limitations/implications
– As a small-scale study of eight atypical firms, the findings cannot be readily generalised. Rather, they provide insight to how eco innovation can address both the environmental and the economic.

Practical implications
– The findings may be useful for those wishing to encourage pro-environmental behaviours and eco innovation among rural SMEs.

Originality/value
– The paper contributes to the currently limited literature on how and why SMEs are implementing pro-environmental practice, and also in relation to greener operational practice and business growth.
Resource flexibility for lean manufacturing: SAP-LAP analysis of a case study
Authors: Chauhan Gulshan , Singh T.P. 
Published: October 2013

Purpose
– Manufacturing industry is under pressure to improve productivity and reducing costs through minimization of wastage of resources. This paper aims to present case study of an automobile component manufacturing company to implement lean manufacturing through resource flexibility and also demonstrate the various areas of future scope for improving lean manufacturing.

Design/methodology/approach
– The case study has been conducted using the flexible system methodology framework. For measuring resource (labor and machine) flexibility and lean manufacturing, various parameters contributing towards labor flexibility, machine flexibility and lean manufacturing are identified. To determine their relative weights, analytical hierarchy process has been employed. A specially designed questionnaire is used to collect the information during case study on different aspects of resource flexibility and lean manufacturing. SAP-LAP analysis has also been carried out, to look into the ways the company is building up resource flexibility and lean manufacturing.

Findings
– Although all parameters of labor flexibility contribute towards overall labor flexibility but ability of workers to work on different machines has the maximum impact of 35.16 percent. Ability of machines to perform diverse set of operations has maximum contribution of 40.38 percent towards machine flexibility. Similarly elimination of waste is 35.15 percent responsible for lean manufacturing implementation. There is also a huge scope to achieve higher degree of lean manufacturing by implementing zero defects, changing attitude towards change and installing flexible machines. It is inferred that 76.2 percent of lean manufacturing is endorsed by resource flexibility.

Research limitations/implications
– The present study includes only labor and machines as the elements of resource flexibility. Other resources may also be included to compute overall resource flexibility.

Practical implications
– The present study provides guidelines to assess the status of resource flexibility and lean manufacturing. According to conclusions, feeble areas in the manufacturing system can be identified and a suitable course of action might be planned for the improvement. Hopefully this study will help the firm's management to identify the problems to manage resource flexibility and implement an effective lean manufacturing.

Originality/value
– In this work, the theoretical perspective has been used not only to update the original instrument, but also to study the subject from a perspective beyond that usually associated with resource flexibility and lean manufacturing.
Lean supply chain practices in the Halal food
Authors: Manzouri Malihe , Nizam Ab Rahman Mohd , Saibani Nizaroyani , Rosmawati Che Mohd Zain Che 
Published: October 2013

Purpose
– This study aims to assess the possibility of implementing lean practices in the Halal food supply chain, and the barriers to their implementation.

Design/methodology/approach
– A survey was used to identify the perceived issues and attitudes towards implementing lean practices in the supply chain. The questionnaire was distributed to 300 Halal food firms in Malaysia. A total of 61 usable replies were received.

Findings
– More than 70 percent of the firms reported that lean supply chain (LSC) has not yet been implemented in their firm. Data analysis shows that 14 percent of non-lean firms urgently need to implement lean manufacturing. Market competition and uncertainty was highlighted as an important barrier in implementing LSC among lean firms. In contrast, lack of customer awareness of LSCM practices was recognised as a major barrier in non-lean firms.

Originality/value
– There is little documentation regarding the status of LSC implementation in the Halal food industries, and therefore identifying the necessity of its implementation and the important impediments was identified as a gap in the existing literature. This paper provides insightful information on the necessity of implementing lean manufacturing practices in Halal food supply chains.
Mentoring frameworks: synthesis and critique
Authors: Dominguez Nora , Hager Mark 
Published: October 2013

Purpose– The purpose of this paper is to present a synthesis of the origins and theoretical frameworks of adult mentoring practices in educational and workplace settings along with an analysis and critique of their application to mentoring processes.Design/methodology/approach– The authors systematically analyzed books and articles published in peer-reviewed journals from 1978 to 2012 using qualitative meta-summary and qualitative meta-synthesis methodological approaches.Findings– This systematic review of the literature resulted first, in an organized, historical framework of theories of adult mentoring in academic and workplace and educational contexts from 1978 to 2012. Second, it provided information regarding the recognized challenges in traditional mentoring endeavors that led to the more expansive concept of developmental networks and participation in communities of practice. Third, it served as a foundation for a critique of the theories as applied to mentoring relationships and programs.Practical implications– The paper provides the theoretical foundation for future empirical work in the field of adult mentoring in educational and workplace settings.Originality/value– This paper is the first to condense the vast theoretical frameworks that inform the field of adult mentoring in the twenty-first century.
Technology's role in fostering transformational educator mentoring
Authors: J. Butler Aaron , S. Whiteman Rodney , M. Crow Gary 
Published: October 2013

Purpose– The purpose of this paper is to expand the current conversation on and research into the potential use of technology as a means of transforming mentoring processes and those engaged in them. The authors examine the manner in which technology is being integrated into mentoring endeavors and the advantages and disadvantages of this tool, arguing that the particular attributes of e-mentoring make it an ideal platform for enhancing mentoring processes and outcomes through the use of new mentoring perspectives. They describe a specific mentoring perspective that could be adopted as a means of critically examining some of the opportunities and challenges of using technology as a tool for transformational mentoring, with an emphasis on mentoring in educational environments.Design/methodology/approach– This conceptual paper uses a constructionist perspective to mentoring as a lens to examine how technology influences the mentoring process and investigates the implications of transformational e-mentoring for educational professionals.Findings– The paper contends that e-mentoring may extend mentoring's horizons to include increasingly broad and diverse constellations of mentors for protégés. With proper guidance, the relationships made possible through e-mentoring can fulfill many mentoring functions and transform both mentors and protégés as they learn from one other.Research limitations/implications– Other than descriptions of mentoring programs that use technological tools, very little research on the outcomes of e-mentoring is available. The paper calls for a greater focus on the outcomes of e-mentoring in future research.Practical implications– The paper discusses the advantages and disadvantages of e-mentoring, presents recommendations for using new technologies to enhance mentoring programs in education and argues for the need to reconsider the purposes and structures of such programs.Originality/value– The paper lays the groundwork for a better understanding of technology's role in mentoring in today's complex, rapidly changing knowledge society.
Does design matter? Affordance perspective on smartphone usage
Authors: Tsai Jo-Peng , Ho Chin-Fu 
Published: October 2013

Purpose
– The aim of this research is to propose a new prospective and methodology to explore how design affordance affects smartphone usage with a contextual approach to investigating the relationship among design features, functional affordance, descriptive beliefs, and inferential beliefs.

Design/methodology/approach
– This research was conducted in two phases to explore the effect of design affordance on adoption of smartphone. In the first phase, the paper investigated how smartphone's innovative design features afford user's functional perception. Subsequently, two affordance-based beliefs – intuition and diversity – were elicited from the design features of smartphone's user interface. In the second phase, a theoretical model was developed and empirically assessed for exploring the effects of the elicited affordance-based variables along with the innovation diffusion theory (IDT) variables on smartphone adoption.

Findings
– Results show that the diversity has significant positive effect on both perceived usefulness and perceived ease of use of smartphone usage. However, the effect of intuition is significant on perceived ease of use but not on perceived usefulness. Of the IDT variables, only relative advantage is statistically significant for attitudes.

Research limitations/implications
– The paper only focused on exploring some innovative design features and associated affordances for smartphone adoption. Other design features should be taken into consideration in future research.

Practical implications
– The result of this research implies that managers or designers should take advantage of the current advanced technology to develop diverse and intuitive design features on smartphone for attracting user's attention and affection.

Originality/value
– There is a contradiction in prior studies concerning the explanations for the causes of ICT artifact adoption while preserving both the generalizability of TAM model and the accuracy and salience to practice. This research contributes a new vision and methodology to explain what and how innovative design features influence user's attitudes towards smartphone usage from the affordance perspective.
Financing through cash-waqf: a revitalization to finance different needs
Authors: Ismail Abdel Mohsin Magda 
Published: October 2013

Purpose
– Recently the revival of the institution of waqf took a movable form especially in terms of the creation of cash waqf which found its ways as one of the financial institutions financing different goods and services in the different countries. In an attempt to enrich the literature on this area, this study is an extension to the authors' work, focusing mainly on the different goods and services provided by different cash waqf schemes in Muslim and Muslim minority countries without depending on the government to provide their needs. The paper aims to discuss these issues.

Design/methodology/approach
– This study uses data collected from primary sources including text from the Hadith, while data collected from secondary sources include books, articles, journals besides web sites and e-books.

Findings
– The findings show the potential of cash waqf in financing not only religious areas but also financing different goods and services needed globally, such as education, health, social care and commercial activates, basic infrastructures, besides opening jobs for the majority of people.

Practical implications
– The expected outcome of this research is to open the door wider for more researchers to explore the potential of cash waqf as one of the instruments to finance all sectors in Muslim and Muslim minority countries without exhausting government budget.

Originality/value
– A revitalization of an old Islamic financial product to meet the different needs.