bluuebunny/crossref_metadata_2025_split huggingface dataset:
1456 – Anxiety And Depression Among Patients With Obesity Referred For Bariatric Surgery
Authors: Emam E. , Osman O.T. 
Published: July 2013

IntroductionThere is a significant prevalence of morbid obesity among the population in the United Arab Emirates (BMI>40kg/m2). This has been accompanied by a growth in bariatric surgery.ObjectivesTo study psychiatric co-morbidity in obese patients seeking Bariatric Surgery.AimsTo identify baseline psychological characteristics such as symptoms of anxiety and depression that may potentially interfere or complicate the surgical procedure.MethodsEighty eight consecutive obese patients (F=69, M=19) seeking bariatric surgery were recruited at Tawam Hospital in Al Ain. Behavioral/psychosocial evaluations were conducted to screen for symptoms of anxiety and depression using Hospital Anxiety and Depression Scale (HAD). The impact on the degree of perceived disability was assessed on the four functional dimensions of the Sheehan Disability Scale (SDS). Statistical methods used Pearson Correlation to study correlation between scales and quantitative variables, while frequencies were determined for categorical variables.ResultsThe reported frequency of significant symptoms on the HAD were 26.7% for anxiety and 14.7% for depression. The average mean disability scores on the SDS were 21.3%. The relative frequency of disabilities on each of the 4 dimensions of functioning were 28.7%, 35.0%, 36.3%, 36.3% consecutively. Higher Depression scores were associated with marked disability on the dimensions of Social life, Family/home responsibilities and Religious duties (0.61, 0.38, 0.29 consecutively). Meantime, anxiety scores were associated with higher disability on social life, family/home responsibilities (0.39 and 0.3) but not on work/school or religious duties.ConclusionAnxiety and depressive symptoms are common among bariatric patients with morbid obesity in the UAE.
1462 – Escitalopram Can Rescue Partly Abnormalities Of Rhythmic System In Major Depressive Patients After 8 Weeks Treatment
Authors: Li S.-X. , Liu L.-J. , Gao L. , Wang X.-F. , Zhang J.-T. , Lu L. 
Published: July 2013

ObjectiveThere are strong links between circadian disturbance and some of the most characteristic symptoms of clinical major depressive disorder (MDD). However there are no published studies of changes in expression of clock genes or of other neuropeptides related to circadian-rhythm regulation, which may influence recurrent susceptibility after treatment with antidepressant in MDD.MethodsBlood samples were collected from twelve healthy controls and twelve male major depressive patients pre- and post- treated with escitalopram for eight weeks at 4-hour intervals for 24 hours. Outcome measures were the relative expression of mRNA of clock genes (hPERIOD1, hPERIOD2, hPERIOD3, hCRY1, hBMAL1, hNPAS2 and hGSK-3beta) and the levels of serum melatonin, Vasoactive Intestinal Peptide (VIP), cortisol, Adrenocorticotropic Hormone (ACTH), Insulin-like Growth Factor-1(IGF-1) and growth hormone (GH) in twelve healthy controls and twelve pre- and post- treated MDD patients.ResultsCompared with healthy controls, MDD patients showed disruptions in diurnal rhythms of expression of hPERIOD1, hPERIOD2, hCRY1, hBMAL1, hNPAS2 and hGSK-3beta, along with disruptions in diurnal rhythms of release of melatonin, VIP, cortisol, ACTH, IGF-1, and GH. Several of these disruptions (hPER1, hCRY1, melatonin, VIP, cortisol, ACTH, and IGF-1) persisted after eight weeks escitalopram treatment, as did elevation of 24-hour levels of VIP and decreases in 24-hour levels of cortisol and ACTH.ConclusionThese persisted neurobiological changes may play a role in MDD symptoms that are thought to contribute to recurrence vulnerability and in maintenance therapy for a long term.
1474 – Executive Functions In First Episode Remitted Patients With Schizophrenia
Authors: Triki R. , Derbel I. , Hajeri S. , Amado I. , Tabbane K. 
Published: July 2013

IntroductionLiterature suggests that schizophrenia (SCZ) could, early in the evolution, involve significant deficits in executive functioning. However, little is known about patients with recent onset first episode. Besides, only few studies focused on symptom-free intervals. Furthermore, most of them included patients on polymedication of antipsychotics including also add on psychotropics.ObjectivesWe aimed to investigate executive dysfunction in first-episode schizophrenia remitted patients with recent onset of the disease, receiving a strict monotherapy of antipsychotics.AimsEnhance the existence of executive dysfunction early in SCZ limiting the impact of relapses, medication and symptoms.Methods25 first episode outpatients with schizophrenia, having less than 3 years illness duration were included. All patients received a monotherapy of antipsychotic with no antidepressant, mood stabilizer, hypnotics or benzodiazepines. 25 healthy participants were matched one by one, according to age and educational level. For clinical evaluation, PANSS was applied. Executive functions were assessed with the Davidson et al. (2006) computerized battery designed to manipulate both inhibition and cognitive flexibility. It encompasses interrelated tasks that enabled us to independently vary demands on these abilities.ResultsCompared to controls, patients showed significant differences in the percentage of correct responses and in reaction time attesting difficulties in inhibition and in cognitive flexibility.ConclusionsOur results emphasize the notion that executive dysfunction in schizophrenia stands for itself early in the disease, cannot be only explained by relapses, duration of the disease, impact of medication nor symptoms.
1481 – New Standards In Schizophrenia Outcomes : Definition Of Therapeutic Remission In Russia Before And After The International Consensus-based Remission Criteria
Authors: Potapov A. 
Published: July 2013

In Russian psychiatry the definition of therapeutic remission includes an interval from full recovery (symptomatic and functional) to marked deficit and can be divided on different clinical types according to leading psychopathology. A standardized concept of remission in schizophrenia, based on dimensional approach, has been proposed (low symptom threshold in the eight core Positive and Negative Syndrome Scale symptoms for at least 6 consecutive months). Recent studies devoted to validation of the international criteria found several limitations.Analysis of limitations and combination of categorical and dimensional approaches allowed developing new standardized clinic- functional criteria of remission within two consecutive studies (1. population study of remission rate with 6-months follow-up period of symptomatic stability in two health care districts of an outpatient service (Moscow); 2. pharmacotherapeutic study in natural routine setting).New criteria of therapeutic remission are based on PANSS and PSP scales providing specific symptom and symptomatic threshold according to ICD-10 diagnosis and contain 8 symptoms of international criteria. It has to note that episodic course with progressive deficit and remittent course of paranoid schizophrenia and schizoaffective disorder were pooled in one remission group because of possibility to achieve minimal level and less for all chosen symptoms. Practically all positive symptoms were excluded from remission criteria for simple and residual schizophrenia. Validation of standardized clinic- functional criteria showed that they covered wider range of stable schizophrenic patients as compared to international criteria of remission and provide more realistic target for modern antipsychotic therapy according to various clinical types and courses of schizophrenia
1482 – Acute Treatment For Patients With Bipolar Depression In a Hospital Setting In Romania
Authors: Dumitru M.M. , Andrei R. , Botezatu C. , Chirita R. , Chirita V. 
Published: July 2013

IntroductionBipolar disorder is a recurrent disease that can be unpredictable. Several guides provide clinicians evidence- based treatment options for bipolar depression.ObjectivesThe main objective of this study is to investigate the most frequently administered combinations of psychotropic substances and focuses on the use of single drugs in hospitalized patients with bipolar depression.AimsTo assess concordance between clinical acute treatment and recommendations of the guides for bipolar depression.MethodsA cross-sectional study was conducted by interviewing and physical examination of a group of 45 consecutive patients who were hospitalized between February 1 and 30 July 2012, in University Hospital of Psychiatry “Socola” and were diagnosed with bipolar depression according to ICD-10 criteria.ResultsIn our cross-sectional study average age of patients with bipolar depression was 55.7 ± 8.55 years, 66.7% female. Average number of drugs received by hospitalized patients with bipolar depression was 1.73 (SD 0.44), which increased to 3 (SD 0.81) drugs if adding sedatives. Classes of drugs most commonly prescribed in the acute treatment were benzodiazepines 86.7%, antidepressants 66.7%, antipsychotics 60% followed by anticonvulsants 40%. Monotherapy had a prevalence of 33.3% of the patients with bipolar depression.ConclusionsCombinations of antidepressants with mood stabilizers and / or atypical antipsychotics are common in every day acute treatment for patients with bipolar depression. Evaluating indications and conditions of polytherapy are critical issues in future studies on the acute treatment on patients with bipolar depression.
1496 – Pathways To Care In Psychiatry, The Example Of The Carpi’s Mental Health Service
Authors: Landi G. , Spattini L. , Visentini C. , Fiorillo A. , Luciano M. , Ferrari S. , Mattei G. 
Published: July 2013

IntroductionStudying the pathways followed by psychiatric patients is important to plan both mental health services organization and training programmes for doctors and psychiatrists.ObjectiveDetecting the main pathways-to-care followed by patients.AimFinding the reasons why patients look for psychiatric help and the main responses given to patients’ problems by psychiatric services. Evaluating the delays occurring along the pathways.MethodsThe study has been done on 420 Italian patients. In one month, patients with a new episode of disease have been included. Each of them has been administered a questionnaire collecting socio-demographical, medical infos and data concerning health workers, timing and delays along the pathways. Diagnosis done using ICD-10 and an Intervention Detection Schedule filled for each patient.ResultsThe Carpi’s sample consists of 43 patients. The 58% has seen the General Practitioner (GP) in the first place, the 19% the hospital doctor (HD), the 16% the psychiatric worker. Nation-widely, most patients have firstly referred to the psychiatrist (34%). In Carpi, the 44% has received a diagnosis of “Neurotic, stress-related and somatoform disorders”. The 93% has been treated with psychotropic medications. The longest pathway has occurred for behavioural syndromes associated with physiological disturbances and physical factors, the shortest for affective disorders.ConclusionsGP, HD and direct access are the 3 main pathways followed by patients. The importance of the GP is confirmed, so as the necessity for training of sanitary workers within the psychiatric field. A greater cooperation between general practice and mental health services should be pursued
1504 – Central Auditory Processing And Audio-vocal Psycholinguistic Abilities In Children With Attention Deficit-hyperactivity Disorder
Authors: Amin O.R. 
Published: July 2013

ObjectiveCentral auditory processing disorders and attention deficit-hyperactivity disorders (ADHD) have become popular diagnostic entities for school-age children. P300 (P3) event-related potential (ERP) putatively reflects central auditory dysfunctions associated with ADHD.Hypothesis and aimDetection of central auditory processing (higher auditory functioning) as measured by P300 in ADHD children. Determine the role of stimulants in central auditory processing and P300 in ADHD children for a better understanding of the nature of the deficit in these children.Participants and methodsForty children with a diagnosis of ADHD according to Diagnostic and Statistical Manual of Mental Disorders, 4th ed. and 39 normal children were included in the study and were subjected to P300 ERP, audio-vocal items of Illinois test of psycholinguistic abilities.ResultsThis study found a significant difference in P300 latency, amplitude, and most of the audio-vocal subtests between the patients and the controls. This difference was obvious in older children for the Illinois test, but was not observed in P300 results.ConclusionThere was a CAPD in children with ADHD (as indicated by Illinois subtests) and higher auditory central cognitive function (indicated by decreased amplitude of P300 and prolonged latency in such children). Audio-vocal abilities are more defective in older children (8-10 years) than in younger children. Children with ADHD should be assessed for CAPD. Stimulants may decrease the P300 latency and hence improve the attentive ability and auditory process.
1512 – Predictors Of Posttraumatic Growth In War Displaced Persons On The Territory Of Bosnia And Herzegovina
Authors: Petrov B. , Klariĉ M. 
Published: July 2013

IntroductionResearches indicate that traumatized people besides development of mental and physical disorders can experience positive changes.ObjectiveInvestigate relationships between war trauma, social support, psychological distress and posttraumatic growth.AimDetermine the predictors of posttraumatic growth in war displaced persons in Bosnia and Herzegovina.MethodsThe test sample was composed of 71 refugees, who were due to war-related events been forced to leave the original residence, and their new residence is on the territory of Bosnia and Herzegovina. Subjects were recruited by snowballing method, and the starting point of inclusion in the study were acquaintances of the medical staff at the Clinical Hospital Mostar. The study used General Demographic Questionnaire, the Harvard Trauma Questionnaire-version for BiH (HTQ), Brief Symptom Inventory (BSI), Social Support Appraisals Scale (SS-A) and Posttraumatic Growth Inventory.ResultsIn the first predictive model (R2=0.053; F=4.889; P=0.030) that included BSI, HTQ and SS-A questionnaires, a linear regression analysis showed that a stronger social support leads to greater posttraumatic growth (standardized β coefficient=0.257; P=0.030), same as greater sensitivity in interpersonal relationships (standardized β coefficient=0.698; P=0.014), while growth in the number of positive psychological symptoms have a negative impact on posttraumatic growth (standardized β coefficient=-1.008; P=0.042). In the second predictive model (R2=0.043; F=1.226; P=0.299), of all demographic factors only the economic status was a significant predictor, where persons with stable economic status had greater posttraumatic growth (standardized β coefficient=0.337; P=0.040).ConclusionSocial support is significant positive predictor of posttraumatic growth, which is also supported by sensitivity in interpersonal relationships.
Treatment Effect Prediction In Panic Disorder Patients - Fmri Study
Authors: Grambal A. , Tüdös Z. , Kamaradová D. , Hluštík P. , Praško J.P. 
Published: July 2013

IntroductionSome patients have a chronic and/or recurrent form of the disorder. Reasons of treatment resistance have been described, but the neurobiological basis of disorder gravity is unclear.ObjectivesExamine if the hyperactivity of right and left amygdala, left posterior cingulate cortex or left dorsolateral prefrontal cortex predict the treatment effect of Cognitive Behavioral Therapy (CBT).AimsThe aim of our study is to test the hypothesis of treatment predictability in panic disorder patients in fMRI.Method24 patients meeting the ICD-10 criteria for panic disorder with or without agoraphobia. Patients were studied in fMRI during the exposition of threat-related words compared with neutral words and emotional faces compared with fixation points. Patients were studied in fMRI scanner before and after CBT treatment. Psychopathology was assessed using Clinical Global Impression rating scale (CGI) and Beck Anxiety Inventory (BAI). Patients were divided into responders and non-responders groups by the 25% reduction in BAI scale.ResultsSignificant reduction of activity was observed in responders on the right amygdala, while the left amygdala decreased activity is lower, and could be the effect of habituation. Incresed activation of left Broca’s area 46, and 45 was negative treatment effect predictor.ConclusionNegative treatment effect predictor is hyperactivity in left dorsolateral prefrontal cortex BA 46 and 45. Positive predictors are higher reactivity of right amygdala for anxious faces, activation of right angular gyrus, right insula, right temporal pole.Supported by the project IGA MZ CR NT 11047-4/2010
1541 – Influence Of Discarnated People In Mental Diseases And Its Respective Approach
Authors: Thiesen S. 
Published: July 2013

The incidence and prevalence of mental diseases are growing throughout the world and their causes are not yet clearly established in spite of the recent advances in modern psychiatry. By using mediumnistic techniques, or the human ability to enter spiritual reality in an objective manner, we have come into contact with spirits and spiritual contexts that have a well defined relationship with each patient. This has happened in healing sessions in Spiritist Centers for patients with different mental diseases, such as depression, autism, schizophrenia and panic disorder.The diagnostic approach to uncover the spiritual aspects of each case happened with the aid of a team of doctors-mediums. In all cases the spirits were of human beings who had lived their lives in the past such as we live ours in the present. They were now in a spiritual reality that is a world parallel to ours. They interfered psychically in the lives of the patients, causing harm and maintaining the symptoms of specific mental diseases.The ties between these spirits and the patients were established in previous lives and old reincarnations. In a non-controlled prospective study of 48 patients with the mental diseases mentioned above, we were able to perceive them and to act in a psychotherapeutic manner with them such that we were able to undo the spiritual ties of each case. This resulted in an evident improvement of a significant percentage of the cases and even resulted in the complete and sustained recovery of many of them.
1552 – Impaired Decoding Of The Flouting Of The Gricean Maxims Mong Schizophrenia Patients
Authors: Varga E. , Schnell Z. , Tényi T. , Simon M. , Hajnal A. , Németh N. , Herold R. 
Published: July 2013

IntroductionPragmatic language skills were examined in schizophrenia patients compared to IQ-matched control subjects measured by the decoding of the flouting of the four Gricean maxims.Methods19 schizophrenic patients and 19 matched controls were evaluated. Five experimental conditions (all included four stories) were used, such as „quantity maxim” (QNM) condition, „quality maxim” (QLM) condition, „relevance maxim” (RM) condition, „manner maxim” (MM) condition and "control” (C) condition. An investigator presented the stories and asked for the hidden communicative intentions. PANSS scores and general intelligence were also measured.ResultsPatients with schizophrenia performed significantly worse than controls in each of the conditions containig the flouting of the Gricean maxims. The response accuracy in the C condition was not differed significantly between the two groups (QNM:p< 0.001; QLM:p< 0.001; RM:p< 0.001; MM:p< 0.001; C:p=0.487). Significant positive correlations were found between QLM and IQ (p< 0.001) and between RM and IQ (p=0.025), and there was no significant correlatios between PANSS scores and response accuracy. Full scale IQ was not differed significantly between the two groups (p=0.095).ConclusionsWe found that a complex pragmatic language deficit exists in schizophrenia. The impairment do not seem to have a relationship with symptom severity. Besides, it seems, that good intellectual function supports pragmatic language skills in schizophrenia.
1560 – Perceived Infant Difficult Temperament And Mothers Psychological Distress
Authors: Bos S.C. , Marques M. , Pereira A.T. , Soares M.J. , Amaral A.P. , Roque C. , Nogueira V. , Valente J. , Azevedo M.H. , Macedo A. 
Published: July 2013

IntroductionA perceived difficult infant temperament has been associated to mothers depressive mood (Beck, 1996; McGrath et al., 2008).ObjectiveTo identify infant difficult temperament dimensions associated to mothers psychological distress.Methods103 mothers (M= 31.9 years, SD=4.10; 68% married, 71.7% primiparae) filled in the difficult infant temperament questionnaire (DITQ; Macedo et al., 2011), two items of the Brief infant sleep questionnaire (number of infant night wakings, duration of infants wakefulness during the night; Sadeh, 2004), the Beck depression inventory-II (BDI-II; Beck et al., 1996; Coelho et al., 2002) and the Postpartum depression screening scale (PDSS; Beck and Gable, 2000; Pereira et al., 2010) when their babies were 3 months of age. DITQ factor analysis with varimax rotation and reliability analyses suggested 2 temperament dimensions: emotional difficulties (irritable baby, cries excessively, difficult to calm down), F1; sleeping problems (baby who has sleeping problems, gives bad nights, has difficulties falling asleep), F2.ResultsDITQ-F1, DITQ-F2 and infants number of night wakings were positively and significantly associated with BDIII/ PDSS total scores. Infants eating problems were not associated with BDI-II or PDSS values. Controlling for mothers severe depressive mood, regression analysis revealed that DITQ F2 was the variable that explained BDI-II total score (R2=.081; p=.011). PDSS total score was predicted by DITQ F2 (R2=.050; p=.030) and number of infant night wakings (R2=.074; p=.010).ConclusionInfants sleeping problems and infants number of night wakings contribute to mothers psychological distress in postpartum.Financial supportAstraZeneca Foundation.
1564 – Reliability And Validity Of The Thai Version Of The Calgary Depression Scale For Schizophrenia
Authors: Suttajit S. , Srisurapanont M. , Pilakanta S. , Charnsil C. , Suttajit S. 
Published: July 2013

ObjectiveThe purpose of this study was to assess the reliability and validity of the Thai version of the CDSS for the evaluation of depression in patients with schizophrenia.MethodSixty patients with schizophrenia according to DSM-IV-TR were recruited in the study. The Thai version of CDSS, the Mongomery and Asberg Depression Scale (MADRS), the Hamilton Depression Rating Scale, 17-item version (HDRS-17), and the Positive and Negative Syndrome Scale (PANSS) were administered. Major depressive episode diagnosed by a psychiatrist according to the DSM-IV-TR was used as a gold-standard.ResultsThe internal consistency of the Thai version of CDSS was very good (Cronbach’s alpha = 0.869). The inter-rater reliability was found to be in substantial agreement with the intra-class correlation coefficient (ICC) of 0.979. The test-retest reliability over a period of three days was high, with the ICC of 0.861. The Thai version of CDSS showed significant correlations with the MADRS (r =0.887), the HDRS-17 (r=0.865) and the PANSS-G6 (r=0.833). The areas under the ROC curves of the CDSS, MADRS, HDRS-17, and PANSS-G6 against the DSM-IV-TR criteria for major depressive episode were 0.993, 0.954, 0.966, and 0.933, respectively. The optimal cut-off scores to discriminate between depressed and nondepressed patients was 6/7, with a sensitivity of 92.31% and specificity of 97.87%.ConclusionThe Thai version of CDSS is a reliable and valid measure for the evaluation of depression in Thai patients with schizophrenia.