bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of proton versus photon adjuvant radiotherapy on overall survival in the management of skull base and spinal chordomas: a National Cancer Database analysis
Authors: El-Hajj Victor Gabriel , Ghaith Abdul Karim , Hoang Harry , Nguyen Ryan H. , Al-Saidi Neil Nazar , Graepel Stephen P. , Atallah Elias , Elmi-Terander Adrian , Lehrer Eric J. , Brown Paul D. , Bydon Mohamad 
Published: August 2024

OBJECTIVE
Chordomas are rare tumors that originate from undifferentiated remnants of the notochord. Currently, there are no established guidelines regarding the choice of adjuvant radiation modality for patients surgically treated for chordomas. Using a nationwide, multicenter database, the authors aimed to compare long-term survival outcomes associated with the use of proton or photon adjuvant therapy for the management of chordomas of skull base and spine.

METHODS
The National Cancer Database (NCDB) was queried for chordoma cases from 2004 to 2017. Patient, tumor, and treatment characteristics were extracted from the database. The primary outcome was overall survival (OS). Kaplan-Meier survival analyses were conducted to investigate differences in outcome on propensity score–matched cohorts of patients treated with proton or photon adjuvant radiotherapy.

RESULTS
Of the 3490 patients available, 424 met the inclusion criteria for this study. In the prematching analysis, patients receiving adjuvant photon therapy were significantly older (median age 57.0 vs 45.0 years, p < 0.001) and were more commonly male (61% vs 43%, p < 0.001) compared with those receiving proton therapy. Races were equally distributed among radiotherapy modalities (p = 0.64). Patients with chordomas of the mobile spine or sacrum were less likely to receive proton compared with photon therapy (37% vs 58%). Patients receiving proton therapy were more often represented among private insurance holders (69% vs 52%, p < 0.001) as well as in the highest income quartile (52% vs 40%, p = 0.008). Patients traveled farther to receive proton, as opposed to photon, therapy (median 59.0 vs 34.9 miles, p < 0.001). On postmatching Kaplan-Meier analysis encompassing all chordoma cases, no difference in OS between photon and proton therapy was revealed (HR 0.75, 95% CI 0.39–1.44; p = 0.39). A Kaplan-Meier analysis only including patients with skull base chordomas reached similar results (HR 0.83, 95% CI 0.31–2.22; p = 0.71). In patients with spine chordomas, however, a significant difference was found, as proton therapy exhibited a superior OS over photon therapy (HR 0.28, 95% CI 0.09–0.81; p = 0.012).

CONCLUSIONS
Based on this nationwide analysis, patients with private insurance and higher income were more likely to receive proton adjuvant radiotherapy, while those with spinal or sacral chordomas were less likely to receive this modality. Despite this disparity, an OS benefit was observed in patients with chordomas of the spine and sacrum who received adjuvant proton therapy, in comparison with a matched cohort of patients treated with photon therapy. Conversely, this advantageous outcome was not evident in cases of chordomas located at the skull base.
The use of breeding indices when estimating winter durum wheat productivity
Authors: Ivanisova A. S. , Marchenko D. M. 
Published: August 2024

Special attention is currently being paid to the role of genetic and physiological systems that contribute to improving productivity and can be estimated in the form of indices.The current study was carried out in the southern part of the Rostov region at the experimental plots of the FSBSI «ARC “Donskoy”» in 2021–2023 aimed at studying the breeding indices of promising winter durum wheat varieties and lines and their effect on productivity. There have been considered such breeding indices as Mexican, Canadian, ear potential, plant productivity and prospects.Considering the Mexican index, which reflects the capabilities of the mechanical tissues of straw, there have been identified 8 samples Lakomka, Khrizolit, Pridonie, 536/19, 971/19, 1147/19, 1174/19, 1037/17 with high values (0.020–0.023 g/cm) in comparison with the standard variety Kristella. The Canadian index ranged from 4.93 pcs./cm for the standard variety to 7.13 pcs./cm for the variety Khrizolit. According to ear potential index, the varieties and lines varied from 0.082 cm/cm for the standard variety Kristella to 0.097 cm/cm for the line 536/19. The index of prospects shows the ability of straw to transport plastic substances into grain. According to this indicator, the studied samples ranged from 42.7% (the variety Grafit) to 55.4% (the line 536/19). According to the classification, the winter durum wheat varieties and lines varied from low (IPR < 7.0; grain weight per ear was up to 1.5 g) to high productivity (IPR > 11.0; grain weight per ear was more than 2.0 g). In these studies, there was a significant correlation between yield and the ear potential index (r = 0.57 ± 0.22).
The influence of weather conditions on the formation of the winter wheat harvest according to various precursors in the arid zone of Stavropol
Authors: Morozov N. A. , Khodzhaeva N. A. , Prokhorova I. V. , Khripunov A. I. , Obshchiya E. N. 
Published: August 2024

Relevance. The identification of agro meteorological factors that have the greatest impact on the formation of grain yields and their consideration in the improvement of agricultural technologies is an urgent task of agriculture.Methods. The research was carried out in 1972–2023 in the fields of the Prikumsk experimental breeding station in a 6-pole grain-and-grass crop rotation. The purpose of the research is to study the influence of agro meteorological conditions on the formation of the winter wheat harvest according to various precursors for the correction and adaptation of applied agricultural technologies in the arid zone of the Stavropol Territory.Results. The yield of winter wheat significantly depended on precipitation in September — October, moisture reserves by spring, total moisture availability of crops, temperature in May and was determined by the density of plants and the weight of 1000 grains. The maximum yield was formed with precipitation in September — October >117 mm, the highest density of standing (294–392 pcs/m2), spring moisture reserves in the meter soil layer and average total moisture supply for pure steam, respectively, 129–145 mm and 382 mm, occupied steam 115–135 mm and 378 mm and winter wheat 105–125 mm and 342 mm. The minimum duration of the sowing — germination period and the maximum density of standing accounted for a clean and occupied pair for the amount of precipitation for September — October (59–87), and a half-pair >117 mm. Compared with pure steam, the density of standing decreased by an average of 12,2%, the yield by 19,2%, the duration of germination increased 1.4 times, and in repeated crops by 22,6%, 45,3% and 2,7 times, respectively. The mass of 1000 grains had a significant positive relationship with the density of standing by half-steam and a negative one with the average temperature for May — June by pure steam. For half-steam and pure steam, yield is more closely related to the mass of 1000 grains (r = 0.52–0.66) than to the density of standing (r = 0.45–0.50).
Problems of a digital model formation in agriculture
Authors: Plakhin A. E. , Ogorodnikova E. S. , Rostovtsev K. V. 
Published: August 2024

Relevance. The presence of digital gaps slows down the digital transformation of agriculture and, accordingly, slows down the manifestation of the positive effects of digitalization. The identified issues determine the relevance of the study of digital gaps in agricultural sectors.The purpose of the article is to assess the digital gaps that hinder the complex digital transformation of agricultural sectors.Methods. The research methodology is based on theoretical approaches and concepts that substantiate the advantages of digitalization of economic sectors and consider technological progress as the main factors of economic growth. The research methodology involves the identification of intra-industry digital gaps by consistently assessing the level of organizations in the agricultural sector using specific software products and digital technologies that together form a digital model of agriculture.Results. The results showed the presence of significant intra-industry digital gaps, manifested in the proportion of organizations using software products and digital technologies. The lack of integrated use of software products and digital technologies that form the digital model of agriculture leads to low rates of digital transformation, since there is a gap between systems that automatically collect data on the condition of plants and animals, systems of robotic equipment and automatic correction based on artificial intelligence technologies.
Retrospective analysis of data on the prevalence of malignant neoplasms in dogs and cats
Authors: Vilmis D. A. , Melikova J. N. , Chechneva A. V. 
Published: August 2024

The article presents the results of a study on the primary incidence of malignant tumors in dogs and cats in Moscow over the period from January 1, 2023, to July 1, 2024. The study was conducted on the basis of the Department of Diseases of Small Domestic, Laboratory and Exotic Animals and the Research Laboratory of Oncology, Ophthalmology and Animal Biochemistry of the Russian Biotechnological University “ROSBIOTECH”. The study included 208 cats and 325 dogs with primary, spontaneous malignant tumors of various origins. To confirm the diagnosis, a comprehensive approach was used, including clinical examination, hematological tests, and special diagnostic techniques such as ultrasonography, radiography, computed tomography (CT), and magnetic resonance imaging (MRI). Verification of the tumor process was based on cytological and histological methods.The purpose of this work is to analyze the structure of the incidence of small domestic animals with malignant tumors. As a result, we identified the most common types of tumors in cats and dogs. In cats, breast carcinoma was the most common type (44.23%), followed by lymphoma (18.27%), sarcomas (13.46%) and carcinomas (13.94%), as well as squamous cell carcinoma (6.25%). In dogs, breast carcinoma also accounted for the majority of cases (37.23%), along with sarcomas (23.38%), mastocytomas (16.31%), and carcinomas (14.15%).
PENGARUH SIKAP DAN PERILAKU BIDAN TERHADAP PENGETAHUAN IBU HAMIL SAAT PELAKSANAAN ANC
Authors: Agustiarini Anastasya , Aisyah Siti 
Published: August 2024

Latar Belakang: Pelayanan pemeriksaan kehamilan yang sesuai, secara kuantitas dan kualitas diharapkan dapat tercapai tujuan menurunkan angka kematian ibu dengan mendekatkan fasilitas pelayanan ke masyarakat. Kenyataan yang terjadi kunjungan pemeriksaan kehamilan (K4) belum mencapai target, bahkan terjadi penurunan target dari K1.Tujuan Penelitian: Mengetahui pengaruh sikap dan prilaku bidan terhadap pengetahuan ibu hamil saat pelaksanaan ANC. Metode Penelitian: Penelitian ini adalah penelitian observasional dengan pendekatan analitik dengan pengumpulan data menggunakan kuesioner yang dilaksanakan pada bulan april-mei 2019. Populasi penelitian adalah ibu hamil multigravida di wilayah kerja Puskesmas Kuripan dengan sampel 30 ibu hamil. Analisa data yang digunakan yaitu Regression Binary Logistic. Hasil Penelitian : Sikap bidan pada saat pelaksanaan ANC yang positif sebesar 87% Sedangkan perilaku bidan positif sebesar 77%. Berdasarkan indikator tingkat pengetahuan, menunjukkan ibu yang memliki pengetahuan baik sebesar 87%. Dari hasil uji statistik Regression Binary Logistic, nilai pvalue 0,00 nilai sig < 0,05 tolak Ho dan Ha diterima. Kesimpulan : Terdapat pengaruh sikap dan perilaku bidan terhadap tingkat pengetahuan ibu hamil saat pemeriksaan ANC di wilayah kerja Puskesmas Kuripan tahun 2019. AbstractBackground: Proper antenatal care services, in quantity and quality, are expected to achieve the goal of reducing maternal mortality by bringing services to the community closer. The fact that a pregnancy check-up visit (K4) has not reached the target, even the target of K1 has decreased. Research Objectives: To find out the influence of midwives' attitudes and behavior on the knowledge of pregnant women during ANC implementation. Research Methods: This study was an observational study with an analytical approach by collecting data using a questionnaire conducted in April-May 2019. The study population was multigravida pregnant women in the working area of the Kuripan Health Center with a sample of 30 pregnant women. Data analysis used is Binary Logistic Regression. Research Results: Attitudes of midwives at the time of positive ANC implementation were 87% while positive midwives' behavior was 77%. Based on the level of knowledge indicators, mothers who have good knowledge are 87%. From the results of the Binary Logistic Regression test, the value of 0.00 value sig <0.05 rejects Ho and Ha is accepted. Conclusion: There are influences of attitudes and behavior of midwives on the level of knowledge of pregnant women during ANC examination in the working area of the Kuripan Health Center in 2019.
HUBUNGAN STATUS GIZI IBU HAMIL ANEMIA DENGAN PERTUMBUHAN BERAT BADAN JANIN
Authors: Rukmantara Anindita Rahmayanti , Sulianty Ati 
Published: August 2024

AbstrakLatar Belakang: NTB berada pada peringkat ketiga prevalensi stunting tertinggi di Indonesia dengan angka 37,2%. Salah satu penyebab stunting karena kekurangan gizi selama kehamilan yang dapat menyebabkan anemia dan menyebabkan pertumbuhan janin terhambat.Tujuan: Untuk mengetahui hubungan status gizi ibu dengan pertumbuhan berat badan janin pada ibu hamil anemia.Metode: Penelitian ini menggunakan metode Observational Analitik dalam pendekatan Cross Sectional dengan populasi seluruh ibu hamil anemia yang diambil data status gizinya saat kunjungan awal di wilayah kerja UPT BLUD Puskesmas Meninting dengan jumlah sampel 30 orang. Pengambilan sampel dengan Purposive Sampling pada usia kehamilan 21-27 minggu. Pertumbuhan berat badan janin dipantau setiap bulan menggunakan alat USG sebanyak 3 kali oleh dokter Sp.OG yang sama. Uji statistik yang digunakan adalah uji Fisher’s Exact Hasil: Status gizi ibu hamil anemia terbanyak berada pada kategori kurus dengan IMT <18.5 sejumlah 15 orang (50%). Mayoritas pertumbuhan berat badan janin mengalami ketidaksesuaian yakni sejumlah 16 orang (53%) pada pemeriksaan USG ke-1, 17 orang (57%) pada pemeriksaan USG ke-2 serta 18 orang (60%) pada pemeriksaan USG ke-3. Hasil uji statistik menunjukkan bahwa p-value 0,008 (p < 0.05).Kesimpulan: Terdapat Hubungan Antara Status Gizi Ibu dengan Pertumbuhan Berat Badan Janin pada Ibu Hamil Anemia. AbstractBackground: NTB is ranked third in the highest stunting prevalence in Indonesia with 37.2%. One of the causes of stunting due to malnutrition during pregnancy which can cause anemia and fetal growth to be inhibited.Objective: To determine the correlation of maternal nutritional status with fetal weight growth in anemic pregnant women.Method: This study used the Observational Analytical method in the Cross-Sectional approach which the population is anemia pregnant women whose nutritional status data was taken at the initial visit in the working area of Meninting Public Health Center with 30 people as the sample. Sampling used Purposive Sampling with 21-27 weeks gestational age. The growth of fetal weight was monitored every month using an ultrasound device 3 times by the same Sp. OG doctor. The statistical test used is the Fisher’s Exact test.Results: The nutritional status of the most anemia pregnant women were in the thin category with BMI < 18.5 with 15 people (50%). Majority of thefetal weight growth experienced a mismatch, 16 people (53%) on the 1st ultrasound examination, 17 people (57%) on the 2nd ultrasound examination and 18 people (60%) on the 3rd ultrasound examination. The statistical test results show that p-value is 0.008 (p <0.05).Conclusion: There is a correlation between maternal nutritional status and fetal weight growth in pregnant women with anemia.
PENGARUH PENDIDIKAN ANTENATAL DENGAN MEDIA BOOKLET TERHADAP PENGETAHUAN DAN KESIAPAN IBU HAMIL USIA DIBAWAH 20 TAHUN DALAM MENGHADAPI KEHAMILAN
Authors: Nurmayasari Nurmayasari , Ekayani Ni Putu Karunia , Najahah Imtihanatun 
Published: August 2024

Latar Belakang : Data RISKESDAS 2018 didapatkan kehamilan perempuan umur 10-54 tahun yang pernah kawin di NTB yaitu pernah hamil 94,1% dan sedang hamil 5,6%. Untuk kehamilan perempuan umur 10-19 tahun pernah hamil sebanyak 58,8% dan sedang hamil 25,2%. Tujuan Penelitian : Mengetahui pengaruh pendidikan antenatal dengan media booklet terhadap pengetahuan dan kesiapan ibu hamil usia dibawah 20 tahun dalam menghadapi kehamilan. Metode Penelitian : Penelitian ini adalah Quasi experiment dengan one group pretest-posttest. Penelitian ini dilaksanakan bulan Mei-Juni 2019. Populasi dalam penelitian ini ibu hamil usia dibawah 20 tahun bertempat tinggal di wilayah kerja UPT BLUD Puskesmas Gerung yaitu 32 ibu hamil. Sampel 30 ibu hamil. Analisis menggunakan Wilcoxon Sign Rank Test dan Paired Sample T Test. Hasil Penelitian : Responden dalam penelitian ini berusia 16-19 tahun dengan mayoritas pendidikan menengah dan semua bekerja sebagai ibu rumah tangga. Terdapat peningkatan nilai tingkat pengetahuan dan kesiapan dari sebelum dan setelah diberikan intervensi. Hasil uji statistik tingkat pengetahuan dan kesiapan diperoleh nilai p = 0,000 sebelum dan setelah diberikan intervensi, menunjukkan adanya pengaruh pendidikan antenatal terhadap pengetahuan dan kesiapan ibu hamil usia dibawah 20 tahun dalam menghadapi kehamilan.AbstractBackground: Data from RISKESDAS 2018 found that pregnancies of women aged 10-54 years who had been married in NTB were pregnant with 94.1% and were pregnant 5.6%. For pregnancy, women aged 10-19 years have been pregnant as much as 58.8% and are pregnant 25.2%. Research Objectives: To determine the effect of antenatal education with booklet media on the knowledge and readiness of pregnant women under the age of 20 in the face of pregnancy. Research Methods: This study was a Quasi experiment with one group pretest-posttest. The research was conducted in May-June 2019. The population in this study were pregnant women under the age of 20 years living in the work area of the UPT BLUD Puskesmas Gerung, namely 32 pregnant women. Sample of 30 pregnant women. Analysis using the Wilcoxon Sign Rank Test and Paired Sample T Test. Results: Respondents in this study were 16-19 years old with the majority of secondary education and all working as housewives. There is an increase in the value of the level of knowledge and readiness from before and after the intervention is given. The statistical test results of the level of knowledge and readiness obtained p = 0,000 before and after the intervention, showed the influence of antenatal education on the knowledge and readiness of pregnant women under 20 years of age in the face of pregnancy.
PENGARUH RELAKSASI GUIDED IMAGERY AND MUSIC (GIM) TERHADAP TINGKAT KECEMASAN IBU HAMIL RESIKO TINGGI
Authors: Salma Baiq Desi Salma Desi , Meliati Linda 
Published: August 2024

Latar Belakang : Ketakutan dan kecemasan pada wanita hamil sebenarnya adalah hal yang normal tetapi jika tidak dapat diatasi dengan serius, itu akan mempengaruhi dan memberikan efek yang besar bagi ibu dan janin secara fisik dan psikis. Banyak faktor penyebab masih tingginya angka kematian ibu, salah satunya adalah kondisi emosional ibu selama kehamilan hingga kelahiran. Tujuan Penelitian : Mengetahui Pengaruh Relaksasi Guided Imagery And Music (GIM) terhadap tingakat kecemasan ibu hamil resiko tinggi di wilayah kerja Puskesmas Karang Pule Metode Penelitian : Penelitian ini adalah quasi experiment dengan menggunakan rancangan one group pretest-posttest without control group.Penelitian ini dilaksanakan pada bulan Mei 2019. Populasi penelitian ini adalah ibu hamil resiko tinggi di wilayah kerja Puskesmas Karang Pule dan sampel dengan jumlah 30 ibu hamil resiko tinggi .Analisis data menggunakan Wilcoxon Hasil Penelitian : Rata-rata skor tingkat kecemasan ibu hamil resiko tinggi sebelum di berikan relaksasi guided imagery and music (GIM) adalah 50.20,sedangkan rata-rata skor tingkat kecemasan ibu hamil resiko tinggi setelah diberikan relaksasi guided imagery and music (GIM) adalah 35.37.Hasil penelitian menunjukkan adanya pengaruh relaksasi guided imagery and music (GIM) terhadap tingkat kecemasan ibu hamil resiko tinggi (p=0,000). Kesimpulan : Ada pengaruh relaksasi guided imagery and music (GIM) terhadap tingkat kecemasan ibu hamil resiko tinggi AbstractBackground: Fear and anxiety in pregnant women is actually a normal thing but if it cannot be taken seriously, it will affect and provide a great effect for both the mother and the fetus physically and psychologically. Many factors cause maternal mortality on of which is the emotional condition of the mother during pregnancy to birth. Objective: To determine the effect of relaxation Guided Imagery And Music (GIM) on the level of anxiety of high-risk pregnant women in the working area of Karang Pule Health Center Research Method: This study was a quasi experiment using the one group pretest-posttest without control group design. The study was conducted in May 2019. The population was high risk pregnant women in the Karang Pule Health Center work area and a sample of 30 pregnant women high risk. Analyze data using Wilcoxon. Results: The average score of anxiety level of high risk pregnant women before guided imagery and music (GIM) relaxation was 50.20, while the average score of anxiety level of high risk pregnant women after being given guided imagery and music relaxation (GIM) was 35.37 The results of the study showed the influence of guided imagery and music (GIM) relaxation on the anxiety level of high-risk pregnant women (p = 0,000). Conclusion: There is an influence of guided imagery and music (GIM) relaxation on the anxiety level of high-risk pregnant women.