bluuebunny/crossref_metadata_2025_split huggingface dataset:
Si può misurare il benessere? Riflessioni sulla dimensione spaziale del Better Life Index calcolato da OCSE
Authors: Rodeschini Marta 
Published: July 2024

Abstract Can Well-being Be Measured? Reflections on the Spatial Dimension of the OECD Better Life Index Indices developed by international research organizations assume value in the adoption of new policies. This paper aims to present the role that these indices have taken on in order to investigate the methodology adopted and understand the role that the space between the indicators used takes on. Specifically, the Better Life Index that the OECD develops is examined, analyzing and mapping the indicators used. Some critical issues emerge, and in particular the absence of the spatial dimension among the parameters considered. The paper reflects on the relevance of this gap and highlights the importance of the relationship with space in assessing well-being.
Effect of bioceramic intracanal medication on the dentinal bond strength of bioceramic cements: an ex-vivo study
Authors: Almohareb Rahaf A. , Barakat Reem M. , Algahtani Fahda N. , Almohaimel Mshael Ahmed , Alaraj Denah , Alotaibi Norah 
Published: July 2024

Background
The present study evaluated the effect of a bioceramic intracanal medicament (Bio-C Temp) on the push-out bond strength of bioceramic cements.

Methods
Forty-eight human single-canaled premolars were prepared and randomly divided into three groups: Group (A) received no intracanal medicament; Group (B) calcium hydroxide (CH); and Group (C) Bio-C Temp. After medicament removal, the roots were sectioned transversely. The slices in each group were separated into two subgroups (n = 16): in Subgroup (1), mineral trioxide aggregate (MTA) was placed, and in Subgroup (2) Bio-C Repair. Push-out bond strength was determined using a universal testing machine, applying a constant compressive force on the cement until bond failure. The failure mode was also evaluated. Data were analyzed using the Chi-square test and two-way ANOVA followed by Tukey’s post hoc tests. The level of significance was set at 5%.

Results
The pushout bond strength of Bio-C Repair was significantly higher than that of MTA irrespective of intracanal medication (p = 0.005). The placement of Bio-C Temp was associated with significantly lower bond strength (p = 0.002, p = 0.001).

Conclusion
Bio-C Repair showed better bond strength compared to MTA, irrespective of intracanal medication. Bio-C Temp intracanal medicament, however, decreased the bond strength of both these cements.
Effect of Nonthermal Atmospheric Plasma on S. mutans Biofilms
Authors: Silva Héllen Súzany Freire , Lima Adália Samara Gadelha de Holanda , Rodrigues Lidiany Karla Azevedo , Duarte Simone , Zanin Iriana Carla Junqueira 
Published: July 2024

Aims: Verify the effect of non-thermal atmospheric plasma on biofilms under different conditions.
Study Design: In vitro laboratory, Experimental, Randomized.
Place and Duration of Study: Federal University of Ceará, 2 years.
Methodology: Biofilms of Streptococcus mutans UA159 were formed on human enamel slabs, submitted to episodes of sucrose exposure for 5 days. The specimens were randomly divided in 2 different experiments; one submitted to daily plasma treatment of biofilms and other submitted to one-time treatment of the biofilms after 5 days. The samples were divided in nine groups as follows: NT (No treatment), CHX (chlorhexidine 0.12%), NaF (sodium fluoride 0.05%), ARG1 (1 minute argon flow), ARG5 (5 minutes argon flow), ARG10 (10 minutes argon flow), PLA1 (1 minute plasma jet), PLA5 (5 minutes plasma jet), PLA10 (10 minutes plasma jet).
Results: The groups CHX, ARG 1, ARG 5, ARG 10, PLA1, PLA5, PLA10 significantly reduced the bacterial viability in the daily treated biofilms (p <0.001). The same results were only observed in mature biofilms submitted to one time treatment only for the groups PLA5 and PLA10 (p <0.005). The results showed a reduction in soluble extracellular polysaccharides in CHX, ARG and PLA dairy treatments. The percentage of the superficial hardness loss demonstrated a significant reduction only for the CHX group (p <0.05) in daily treatment. In addition, no statistically significant differences were found between the groups before (p = 0.6978) or after treatments (p = 0.8904) in the mineral profile of the specimens by Raman Spectroscopy. Also, scanning electron microscopy showed no difference in the topographic of the treated enamel surface.
Conclusion: Dairy ARG or PLA treatments were effective in reducing the number of viable bacteria and the concentration of water-soluble polysaccharide in the S. mutans biofilms. For the one-time treatment of mature biofilms only PLA5 and PLA10 treatments were effective. No alteration in the surface of the enamel was observed on tested conditions.
Improving MSMEs Performance through Human Capital, Financial Literacy and Competitive Advantage
Authors: Hanifah Ghefira , Innayah Maulida Nurul 
Published: July 2024

Aims: This study aimed to ascertain this effect of Human Capital and Financial Literacy on MSME Performance with Competitive Advantage as a mediating variable.
Study Design: This study was quantitative. The methods of analysis employed in this research were outer and inner models, bootstrapping analysis, and specific indirect effects.
Place and Duration of Study: The study's sample, which was MSMEs in Banyumas Regency, Central Java, Indonesia. Moreover, the duration of this study was 3 months.
Methodology: This study utilized Structural Equation Modeling (SEM) based on Partial Least Square (PLS), this consists of the inner model and the outer model. With a mediation test using indirect effect. Purposive sampling, which used 162 respondents, was the sample strategy employed in this study.
Results: The results showed how Human Capital and Competitive Advantage have a positive and significant effect on the Performance of MSMEs. Furthermore, the mediating test results showed that Competitive advantage has been able to mediate the connection between Human Capital and MSME Performance. However, the results of this study found that Financial Literacy has no effect on MSME Performance and Competitive Advantage. In addition, the results showed that Competitive Advantage has not been able to mediate the relationship between Financial Literacy and MSME Performance.
Conclusion: This research shows that a number of factors, such as Competitive Advantage and Human Capital, affect MSMEs' Performance. The results were in accordance with Resource Based Theory's concept that managing an organization’s human capital, will create a competitive advantage that will increase organizational performance. Therefore, MSMEs need to pay attention to their human capital competencies because. Findings from this research show there is human capital can create competitive advantages that are used in facing competition to improve MSME performance.
Studies on the Effect of Weed Management Practices on Growth, Yield and Quality Parameters of Okra (Abelmoschus esculentus L. Moench.) c.v. Azad Bhindi-1
Authors: Gautam Anoop Kumar , Singh Ram Batuk , Rajiv  , Singh D. P. , Sindhesh  , Goyal Ankit Kumar , Maurya Sandeep , Verma Sanjay 
Published: July 2024

The present investigation was conducted at Vegetable Research Farm, Chandra Shekhar Azad University of Agriculture and Technology, Kanpur during kharif season 2023. The experiment was laid out in Randomized Block Design with eight different treatments viz. T1: Weed check control. T2: Pre-emergence application of pendimethalin @6ml/L. T3: Postemergence application of metribuzin @525g/ha. T4: Pre-emergence application of pendimethalin @6ml/L. + 1 hand weeding at 40 DAS T5: Postemergence application of metribuzin @525g/ha at 25 DAS+ 1 hand weeding at 60 DAS. T6: Pre-emergence application of pendimethalin @6ml/L.+ Postemergence application of metribuzin @525g/ha, T7 Weed free check {three hand weeding} at 20,40,60 DAS respectively, T8: Pre-emergence application of pendimethalin @6ml/L.+ Postemergence application of metribuzin @525g/ha+ One hand weeding 40 DAS replicated thrice. The okra variety ‘Azad Bhindi-1’ was used in experiment. The result of the study revealed that at 30 DAS maximum plant height (30.10cm) was reported in treatment T6, and 60 and 90 DAS maximum plant height (76.50 and 110.00 cm) was reported in T8 and at 30 days maximum number of nodes on main stem of plant (8.70) found in T6, whereas at 60 and 90 DAS maximum number of nodes on main stem of plant (17.80 and 20.50) was reported in T8 . At 30 days maximum diameter of stem(1.30 cm) was reported in treatment T6 , and at 60 and 90 DAS maximum diameter of stem(1.90 and 2.50 cm) reported in T8, at 30 days maximum number of leaves/plant (8.80) is reported in T6 and at 60 and 90 days maximum number of leaves/plant (2.27 and 4.76) is was reported in T8. At 60 and 90 DAS Maximum number of branches per plant (4.90 and 5.96) was found in T8 Maximum Pod diameter (1.80 cm), fruit weight (13.55 gm), pod length (14.30 cm), number of pods per plant ( 25.74 ), pod yield per plant ( 285.00 gm) , pod yield per hectare (16.50 t), TSS ( 3.18 0Brix), crude fibre (8.65 %) and chlorophyll content (1.22 mg) were reported in T8.
Silane Deuteration Catalyzed by Ruthenium Bis(dihydrogen) Complexes or Simple Metal Salts
Authors: Smart Katharine A. , Mothes‐Martin Emmanuelle , Annaka Tatsuro , Grellier Mary , Sabo‐Etienne Sylviane 
Published: February 2014

AbstractThe deuteration of a diverse group of silanes: alkyl‐, aryl‐, alkoxy‐ and chlorosilanes, siloxane and silazane, under an atmosphere of dideuterium (D2) was explored with ruthenium bis(dihydrogen) dihydride complexes and hydrated metal salts. Deuterium incorporation of greater than 97% for the silanes O(SiMe2H)2, Et3SiH, (EtO)3SiH and Me2ClSiH was possible with 0.1 mol% of the ruthenium complex [RuH2(η2‐H2)2(PCyp3)2] [0.05 mol% for O(SiMe2H)2] when catalysis was conducted in the neat silane at 30 °C under 1 bar of D2 for 3.5 h. The air‐stable ruthenium trichloride salt RuCl3⋅x H2O was also an efficient catalyst for the deuteration of O(SiMe2H)2 and Et3SiH; deuterium incorporations for the two silanes of 93% and 90%, respectively, were possible under the same conditions as for [RuH2(η2‐H2)2(PCyp3)2] with 0.1% catalyst loading. Hydrogen–deuterium exchange of O(SiMe2H)2 catalyzed by the rhodium trichloride (RhCl3⋅x H2O) and iridium trichloride (IrCl3⋅x H2O) was similarly efficient as with RuCl3⋅x H2O although catalytic alacrity dropped for Et3SiH.magnified image
Antikörper‐Wirkstoff‐Konjugate: ein neues Konzept in der Krebstherapie
Authors: Chari Ravi V. J. , Miller Michael L. , Widdison Wayne C. 
Published: February 2014

AbstractHerkömmliche Chemotherapeutika gegen Krebs gehen oft mit einer systemischen Toxizität im Patienten einher. Einen alternativen, tumorselektiven Behandlungsansatz bieten monoklonale Antikörper gegen Antigene oder Krebszellen. Allerdings sind die meisten monoklonalen Antikörper nicht wirksam genug, um allein für sich therapeutisch aktiv zu sein. Antikörper‐Wirkstoff‐Konjugate (ADCs) verwenden Antikörper, um eine potente cytotoxische Verbindung selektiv zu Tumorzellen zu befördern, und erhöhen so die therapeutische Breite chemotherapeutischer Wirkstoffe. Die kürzlich erfolgte Zulassung zweier ADCs, Brentuximab Vedotin und Ado‐Trastuzumab Emtansin, zur Krebsbehandlung hat dem Forschungsinteresse auf diesem Gebiet weiteren Schub verliehen. Dieser Aufsatz beschreibt, wie die Erkenntnisse aus Studien an den ADCs der ersten Generation zu erfolgreichen Verbesserungen aller Komponenten – Antikörper, cytotoxische Verbindung und Linker – geführt haben. Die Ausgestaltung von in der klinischen Entwicklung befindlichen ADCs sowie Ergebnisse mechanistischer Studien und präklinischer und klinischer Tests werden diskutiert, ebenso wie neu aufkommende Technologien, die zu weiteren Fortschritten in diesen aufregenden Gebiet führen werden.
Influence of the single‐strand linker composition on the structural/dynamical properties of a truncated octahedral DNA nano‐cage family
Authors: Iacovelli Federico , Alves Cassio , Falconi Mattia , Oteri Francesco , de Oliveira Cristiano L. P. , Desideri Alessandro 
Published: February 2014

ABSTRACTThe structural/dynamical properties of three truncated octahedral DNA nano‐cages composed by identical double helices but single strand linkers with different composition, namely 7 thymidines, 7 adenines, and 7 alternated thymidines and adenines, have been investigated through classical molecular dynamics simulations. Trajectories have been analyzed to investigate the role of the linkers in defining nano‐cages stability and flexibility, including possible influence on the internal cages motions. The data indicate that the cages behavior is almost identical and that the structural/dynamical parameters measured along the trajectories are not particularly affected by the presence of different bases. These results demonstrate that the constraints imposed by the nano‐structure geometry are the main factor in modulating these properties. © 2014 Wiley Periodicals, Inc. Biopolymers 101: 992–999, 2014.
Ruthenium–Nitrosyl Complexes Derived from Ligands Containing Two Carboxylate Functional Groups and Studies on the Photolability of Coordinated NO
Authors: Ghosh Kaushik , Kumar Sushil , Kumar Rajan 
Published: February 2014

AbstractRuthenium complexes [RuIII(L1)(PPh3)2(Cl)] (1) and [RuIII(L2)(PPh3)2(Cl)] (2) (in which L1H2 and L2H2 are iminodiacetic acid and pyridine‐2,6‐dicarboxylic acid, respectively, and H stands for a dissociable proton) derived from the ligands that contain two carboxylate groups were synthesized and characterized. These complexes were treated with in situ generated NO derived from acidified nitrite solution, which afforded the formation of two {Ru–NO}6 complexes [Ru(L1)(PPh3)2(NO)](ClO4) (1a) and [Ru(L2)(PPh3)2(NO)](ClO4) (2a). The molecular structure of the representative complex [Ru(L2)(PPh3)2(NO)](ClO4) (2a) was determined using X‐ray crystallography. Characterization of complexes 1a and 2a by IR and NMR spectroscopic studies revealed the presence of {Ru–NO}6 species with S = 0 ground state. ESI‐MS data also supported the formation of 1a and 2a. Exposure to UV light promoted rapid loss of NO from both ruthenium nitrosyls to generate RuIII photoproducts of the type [Ru(L)(PPh3)2(S)](ClO4) (in which S stands for solvent). The quantum yields of NO photorelease for complexes 1a and 2a were measured using a chemical actinometry study. The NO released in solution was estimated using the Griess reagent, and the results were compared with the data obtained from sodium nitroprusside (SNP). A 2,2‐diphenyl‐1‐picrylhydrazine (DPPH) radical quenching assay was performed to estimate the amount of generated reactive nitrogen species and/or reactive oxygen species under aerobic conditions during photolysis of NO.
Hexachloroplatinate(IV) Anion Induced Cucurbituril Supramolecular Assembly with Linear Channels
Authors: Ji Ning‐Ning , Cheng Xiao‐Jie , Zhao Yi , Liang Li‐Li , Chen Kai , Xiao Xin , Zhang Yun‐Qian , Zhu Qian‐Jiang , Xue Sai‐Feng , Tao Zhu 
Published: February 2014

AbstractIn the present work, we demonstrate the formation of a typical cucurbit[6]uril (Q[6])‐based porous material in the presence of the hexachloroplatinate(IV) anion [PtCl6]2– as an inorganic structure inducer. The driving forces for the structure directing effect of the [PtCl6]2– anion could be attributed to ion–dipole and hydrogen‐bonding interactions between the anion and the ≡CH or =CH2 groups on the back of the Q[6] molecule.
Total Synthesis of Unsymmetrical Benzils, Scandione and Calophione A
Authors: Worayuthakarn Rattana , Boonya‐udtayan Sasiwadee , Ruchirawat Somsak , Thasana Nopporn 
Published: February 2014

AbstractThe synthesis of the title unsymmetrical benzils, scandione and calophione A, is described. The key processes involve intramolecular cyclization reaction of the carbanion at the benzylic position of the arylbenzyl ether to the adjacent ester group followed by oxidation. The palladium(II)‐catalyzed oxidative cyclization was also used to establish the benzofuran unit of calophione A.
Synthesis of 1,2,3‐Trisubstituted Cyclopentannulated Benzothiophenes through an Acid‐Mediated, Solvent‐Free, One‐Pot Domino Process
Authors: Satpathi Bishnupada , Dhiman Seema , Ramasastry S. S. V. 
Published: February 2014

AbstractThe synthesis of 1,2,3‐trisubstituted cyclopenta[b]thiophenes was achieved through a Brønsted acid mediated domino process under solvent‐free conditions. In this one‐pot process, benzothienylation of 1,3‐dicarbonyls follows an intramolecular aldol‐type reaction leading to the generation of functionalized and highly substituted annulated benzothiophenes. This class of compounds find potential applications in molecular electronics and exhibit significant biological activities. A brief theoretical investigation established a significant relationship between the energy of the regioisomers and their distribution.
Probabilistic risk analysis of structural impact in seismic events for linear and nonlinear systems
Authors: Chase J. Geoffrey , Boyer Florent , Rodgers Geoffrey W. , Labrosse Gregoire , MacRae Gregory A. 
Published: February 2014

SUMMARYEarthquake‐induced structural pounding is a significant risk for buildings in densely populated cities and for other applications, such as adjacent bridge deck sections of long‐span bridges. Although significant research has been undertaken into structural pounding, this manuscript focuses on a parametric, probabilistic study of the likelihood of structural pounding occurring while also quantifying the likelihood of that impact leading to displacement increase in the structures involved. Additional metrics are also used to define minimum gap ratios (GRs) (expressed in relation to structure spectral displacements) that are required to avoid impact occurring, or to limit the magnitude of displacement increases that result from impact. The parametric study also includes the influence of structural nonlinearities, such as the coefficient of restitution during impact and the influence of column inelasticity.Results indicate that the probability of impact between structures increases as the GR decreases and structural period differences increase. The same general behavior was noticed for the risk of increasing displacement because of impact. An increase in the coefficient of restitution leads to an increase in the risk of increased displacement response. The inclusion of nonlinear column behavior leads to a drop in both probability of impact occurring and the risk of increasing displacement response, as compared with the same structures without impact occurring. The results presented also indicate that the likelihood of an increase in displacement response because of structural pounding is independent of the gap ratio for smaller GR values. Above this value of GR, the reduction of impacts leads to a smaller probability of a displacement increase. Finally, a probabilistic design metric is presented using these results that assesses risk of significant displacement increase because of impact above a set design limit to the gap ratio.Overall, this study utilizes a simplified, two degree‐of‐freedom structural model, but presents a parametric study to investigate the probabilistic risk analysis of building pounding and the associated effect on building response with a focus on use in design or the retrofit of structures. Copyright © 2014 John Wiley & Sons, Ltd.
Effect of ester compounds on biogas production: beneficial or detrimental?
Authors: Yanti Heri , Wikandari Rachma , Millati Ria , Niklasson Claes , Taherzadeh Mohammad J. 
Published: February 2014

AbstractEsters are major flavor compounds in fruits, which are produced in high volume. The widespread availability of these compounds in nature attracts interest on their behavior in anaerobic digestion in waste and wastewater treatments. The aim of this work was to study the effects of various esters at different concentrations in anaerobic digestion followed by determination of their minimum inhibitory concentration (MIC), and to study the effect of chain length of functional group and alkyl chain of ester on methane production. Addition of methyl butanoate, ethyl butanoate, ethyl hexanoate, and hexyl acetate at concentration up to 5 g L−1 increased methane production, while their higher concentrations inhibited the digestion process. The MIC values for these esters were between 5 and 20 g L−1. Except hexyl acetate, the esters at concentration 5 g L−1 could act as sole carbon source during digestion. For ethyl esters, increasing number of carbon in functional group decreased methane production. For acetate esters, alkyl chain longer than butyl inhibited methane production. Effect of ester on methane production is concentration‐dependent.
Effect of induction chemotherapy on swallow physiology and saliva production in patients with head and neck cancer: A pilot study
Authors: Mittal Bharat B. , Pauloski Barbara Roa , Rademaker Alfred W. , Discekici–Harris Muveddet , Helenowski Irene B. , Mellot Ann , Agulnik Mark , Logemann Jerilyn A. 
Published: February 2014

AbstractBackgroundNo objective data are available to assess the potential damage induction chemotherapy alone contributes to swallowing physiology and salivary production in patients with locally and regionally confined head and neck cancer.MethodsThirteen patients with head and neck cancer were evaluated preinduction and postinduction chemotherapy. Assessment included: (1) percentage of nutrition taken orally and food consistencies in diet; (2) videofluorographic swallow evaluation; (3) whole mouth saliva collection; (4) quality‐of‐life questionnaire; and (5) pain and oral mucositis scores.ResultsAll patients were able to consume most foods and took 100% of their nutrition orally both preinduction and postinduction chemotherapy. Although a number of swallow measures worsened, no statistically significant differences were observed in diet, quality of life measures, pain, or saliva weight, or in most temporal swallow measures. Pharyngeal residue decreased significantly after chemotherapy.ConclusionInduction chemotherapy alone did not significantly negatively alter swallowing physiology and salivary secretion, although the trend was toward worsening in function. © 2014 Wiley Periodicals, Inc. Head Neck 37: 567–572, 2015
Redox Properties of Benzoquinone Ansamycins in Aqueous Solutions
Authors: Samuni Amram , Goldstein Sara 
Published: February 2014

AbstractGeldanamycin (GM) is an inhibitor of heat shock protein 90 (Hsp90) with potent and broad anti‐cancer properties, but with unacceptable levels of hepatotoxicity. These characteristics have led to the devise of a range of less toxic GM structural analogues. Redox properties and thiol reactivity are central to the therapeutic and toxicologic effects of quinones, and the question arises as to whether the toxicity of GM and its analogues relates to the reduction potential of the quinone. Using pulse radiolysis, we have previously determined the one‐electron reduction potentials (vs. the normal hydrogen electrode [NHE]) at pH 7.0 of GM, 17‐(dimethylaminoethylamino)‐17‐demethoxygeldanamycin (17‐DMAG), and 17‐allylamino‐17‐demethoxygeldanamycin (17‐AAG) to be −62±7 mV, −194±6 mV, and −273±8 mV, respectively. These experimental results are now used to establish a predictive relationship for the reduction potential of GM analogues based on the Hammett para substituent constants. These values correlate well with the drugs effects in vivo. We show that cytotoxicity of the benzoquinone ansamycin increases as its respective reduction potential increases, even after blocking of the C19‐position from nucleophilic addition. We conclude that the cytotoxicity is directly related to the reduction potential of the quinone/semiquinone couple.