bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Magnetic Nanoparticles (CoFe2O4)‐Supported Phosphomolybdate as an Efficient, Green, Recyclable Catalyst for Synthesis of β‐Hydroxy Hydroperoxides.
Authors: Li Pei‐He , Li Bao‐Le , An Zhi‐Min , Mo Li‐Ping , Cui Zhen‐Shui , Zhang Zhan‐Hui 
Published: April 2014

AbstractInterestingly, the substitution of epoxides (I) and (III) exerts a significant effect on the ring‐opening direction.
ChemInform Abstract: Electrophilic Difluoro(phenylthio)methylation: Generation, Stability, and Reactivity of α‐Fluorocarbocations.
Authors: Betterley Nolan M. , Surawatanawong Panida , Prabpai Samran , Kongsaeree Palangpon , Kuhakarn Chutima , Pohmakotr Manat , Reutrakul Vichai 
Published: April 2014

AbstractFor the first time, a direct method for electrophilic difluoro(arylthio)methylation of allylsilanes is developed and the chemical and theoretical evidence for α‐difluorocarbocations as the reactive species are provided.
ChemInform Abstract: One‐Pot Synthesis of Aryl Biaryl Sulfones.
Authors: Chang Meng‐Yang , Wu Ming‐Hao , Chan Chieh‐Kai , Lin Shin‐Ying 
Published: April 2014

AbstractA facile one‐pot protocol allows the synthesis of sulfonyl biphenyls via NaH‐mediated domino annulations of cinnamaldehydes with propargylic sulfones.
ChemInform Abstract: Asymmetric Sonogashira Coupling with a Chiral Palladium Imidazoindole Phosphine Complex.
Authors: Zhou Haifeng , Uozumi Yasuhiro 
Published: April 2014

AbstractOptimized conditions including a chiral imidazoline phosphine ligand allows the monoalkynylation of substrates (I) and (IV) to afford the axially or planary chiral products.
ChemInform Abstract: An Effective Dual Copper‐ and Sulfide‐Catalytic System for the Epoxidation of Aldehydes with Phenyldiazomethane.
Authors: Pereira Ana , Martin Carmen , Maya Celia , Belderrain Tomas R. , Perez Pedro J. 
Published: April 2014

AbstractHomoscorpionate ligands, with organic sulfides as cocatalyst, promote the reaction of phenyldiazomethane (II) with aldehydes (I) to form epoxides (III), with activities exceeding or, at least similar to those of reported rhodium‐based systems.
ChemInform Abstract: Synthesis of 2‐Alkynyltetrahydrofuran Derivatives from Tetrahydrofuran and Alkynyl Bromides.
Authors: Yang Yuan , Huang Hui , Zhang Xiaoyun , Zeng Weilan , Liang Yun 
Published: April 2014

AbstractThe reaction proceeds under transition metal‐free conditions For the first time NaF is found to promote this functionalization reaction.
ChemInform Abstract: Microwave Promoted Diastereoselective Synthesis of Dihydroindeno[1,2‐b]furans via One‐Pot Three‐Component Reaction in Solvent‐Free Conditions.
Authors: Majumder Swarup , Sharma Meenakshi , Bhuyan Pulak J. 
Published: April 2014

AbstractA convenient protocol is developed for the microwave‐assisted reaction of 1,3‐indanedione, pyridinium ylide, and aromatic aldehydes to afford the title compounds diastereoselectively.
ChemInform Abstract: Amino Acid‐Derived Phosphonium Salts‐Catalyzed Michael Addition of 3‐Substituted Oxindoles.
Authors: Wu Xiaoyu , Liu Qin , Liu Yong , Wang Qun , Zhang Ying , Chen Jie , Cao Weiguo , Zhao Gang 
Published: April 2014

AbstractNovel enantiopure phosphonium phase transfer catalysts derived from amino acids are developed.
ChemInform Abstract: Vinylogous Organocatalytic Triple Cascade Reaction: Forging Six Stereocenters in Complex Spiro‐Oxindolic Cyclohexanes.
Authors: Chatterjee Indranil , Bastida David , Melchiorre Paolo 
Published: April 2014

AbstractA three‐component domino process via amino‐catalyzed Michael addition/1,6‐addition/vinylogous aldolization allows the synthesis of the title species.
ChemInform Abstract: Copper‐Catalyzed Tandem Intramolecular Cyclization/Coupling Reaction: Solvent Effect on Reaction Pathway.
Authors: Yamashita Mitsuaki , Noro Toshiaki , Iida Akira 
Published: April 2014

AbstractA simple and mild protocol is developed for the synthesis of 3‐substituted indoles from o‐alkynylanilines and copper salts via tandem intramolecular cyclization/coupling reaction.
ChemInform Abstract: Iron(III)‐Catalyzed Synthesis of 1,2,4‐Trisubstituted Imidazoles Through the Reactions of Amidines and Aldehydes in Air.
Authors: Liu Xiang , Wang Dong , Chen Yongxin , Tang Dong , Chen Baohua 
Published: April 2014

AbstractA wide range of tri‐ and tetrasubstituted imidazole derivatives is prepared from amidines, aldehydes and nitromethane or nitroethane, respectively.
ChemInform Abstract: Phosphine‐Catalyzed [3 + 2] Annulation of Electron‐Deficient Alkynes with N‐Hydroxyphthalimide: Synthesis of 3a‐Hydroxyisoxazolo[3,2‐a]isoindol‐8(3aH)‐ones.
Authors: Zhou Qing‐Fa , Chu Xue‐Ping , Ge Fei‐Fei , Wang Yue , Lu Tao 
Published: April 2014

AbstractThe products are of high biological importance and are prepared in high yields under mild conditions from readily available substrates.
ChemInform Abstract: Alkylation of 4(5)‐Nitro‐1,2,3‐triazole with Alcohols in Strongly Acidic Media.
Authors: Sakovich G. V. , Sukhanov G. T. , Filippova Yu. V. , Sukhanova A. G. , Bosov K. K. 
Published: April 2014

AbstractThe alkylation of the title compounds occurs at all three endocyclic N‐atoms leading to a mixture of N(1)‐, N(2)‐, and N(3)‐alkyl‐4‐nitro‐1,2,3‐triazoles.
ChemInform Abstract: Synthesis of New Furopyrans (III) and Angularly Fused Furopyranochromenes (V) from 3‐Arylmethylidenefuran‐2‐ones.
Authors: Anis'kova T. V. , Egorova A. Yu. 
Published: April 2014

AbstractThe title compounds (III), (V) are obtained in reactions of appropriate 5‐aryl‐3‐arylmethylidenefuran‐2‐ones (I) or (IV) with malononitrile.
ChemInform Abstract: Synthesis of a Novel Piperidine‐Functionalized Poly(ethylene glycol) Bridged Dicationic Ionic Liquid and Its Application in One‐Pot Synthesis of Substituted 2‐Amino‐2‐chromenes and 3,4‐Dihydropyrano[3,2‐c]chromenes in Aqueous Media.
Authors: Wang Yinglei , Luo Jun , Xing Tantan , Liu Zuliang 
Published: April 2014

AbstractThe novel bridged dicationic ionic liquid shown is found to be an efficient and recyclable catalyst for the synthesis of the title chromenes (IV), (VI), and (VIII) via one‐pot three‐component reactions of appropriate activated “phenols” with malononitrile and aromatic aldehydes.
ChemInform Abstract: Imidazole Functionalized Magnetic Fe3O4 Nanoparticles as a Novel Heterogeneous and Efficient Catalyst for Synthesis of Dihydropyrimidinones by Biginelli Reaction.
Authors: Nazari Simin , Saadat Shervin , Fard Pegah Kazemian , Gorjizadeh Maryam , Nezhad Eshagh Rezaee , Afshari Mozhgan 
Published: April 2014

AbstractImidazole‐coated magnetic Fe3O4 nanoparticles work as an effective, reusable and easily available catalyst for the one‐pot three‐component condensation reaction of aldehydes, 1,3‐dicarbonyl compounds, and urea under solvent‐free conditions.
ChemInform Abstract: A Phosgene and Peroxide‐Free One‐Pot Tandem Synthesis of Isatoic Anhydrides Involving Anthranilic Acid, Boc Anhydride, and 2‐Chloro‐N‐methyl Pyridinium Iodide.
Authors: Verma Chhaya , Sharma Somesh , Pathak Arunendra 
Published: April 2014

AbstractAn operationally simple and scalable three‐step one‐pot protocol is presented for the synthesis of isatoic anhydrides via N‐Boc protection of anthranilic acid derivatives followed by 2‐chloro‐N‐methyl pyridinium‐promoted cyclization.
ChemInform Abstract: Regioselective Synthesis of Oxepinones and Azepinones by Gold‐Catalyzed Cycloisomerization of Functionalized Cyclopropyl Alkynes.
Authors: Fernandez‐Garcia Jesus M. , Garcia‐Garcia Patricia , Fernandez‐Rodriguez Manuel A. , Perez‐Anes Alexandra , Aguilar Enrique 
Published: April 2014

AbstractA regioselective synthesis of title compounds (II) and (IV) in good to excellent yields from alkynylcyclopropanecarboxylic acid derivatives (I) and (III) is reported.
ChemInform Abstract: Laccase‐Catalyzed Homocoupling of Primary Aromatic Amines Towards the Biosynthesis of Dyes.
Authors: Sousa Ana Catarina , Martins Ligia O. , Robalo M. Paula 
Published: April 2014

AbstractColored disubstituted benzoquinonimine trimeric structures (II), (IV), and (VII) are obtained as main products of the oxidation of 4‐electron donor primary amines (I), (III), and (VI), resp., using oxidoreductive laccases.
ChemInform Abstract: Hafnium(IV) Tetratriflate in Selective Reductive Carbohydrate Benzylidene Acetal Opening Reaction and Direct Silylation Reaction.
Authors: Manabe Shino , Ito Yukishige 
Published: April 2014

AbstractThe selective reductive carbohydrate benzylidene acetal opening with triethylsilane and hafnium(IV) triflate as the catalyst provides mixtures of the corresponding alcohols and triethylsilyl ethers.
ChemInform Abstract: A Versatile Method to Prepare Difluorinated Primary Alcohols and its Application to the Syntheses of Novel Acyclic Fluorinated Nucleosides.
Authors: Tse Bruno 
Published: April 2014

AbstractA four‐step sequence is presented for the conversion of ketone (I) into difluorinated alcohol (VI), which is further transformed into nucleoside (VIII), the difluoro‐analogue of ganciclovir and penciclovir.
ChemInform Abstract: Facile Synthesis of 6‐(Heptadec‐8‐enyl)thiopyrimidines Incorporating Glycosyl Moiety and Their Antitumor Activity.
Authors: Abd El Salam Hayam A. , Yakout El‐Sayed M. A. , El‐Hashash M. A. , Nawwar Galal A. M. 
Published: April 2014

AbstractA New series of pyrimidine S‐ and N‐glycosides, [cf.
ChemInform Abstract: Shape‐Directed Platinum Nanoparticle Synthesis: Nanoscale Design of Novel Catalysts.
Authors: Leong G. Jeremy , Schulze Maxwell C. , Strand Matthew B , Maloney David , Frisco Sarah L. , Dinh Huyen N. , Pivovar Bryan , Richards Ryan M. 
Published: April 2014

AbstractReview: recent findings reported since 2009 focusing on methods for shape control as well as effects of exposed surface facets on the selectivity of catalytic reactions; 208 refs.
ChemInform Abstract: Subphthalocyanines, Subporphyrazines, and Subporphyrins: Singular Nonplanar Aromatic Systems
Authors: Claessens Christian G. , Gonzalez‐Rodriguez David , Rodriguez‐Morgade M. Salome , Medina Anais , Torres Tomas 
Published: April 2014

AbstractReview: synthesis, characterization, properties, and applications, 444 refs.
ChemInform Abstract: Five‐Membered Ring Systems: With O and N Atoms
Authors: Cordero Franca M. , Giomi Donatella , Lascialfari Luisa 
Published: April 2014

AbstractReview: novel reaction chemistry and new ring synthetic methods for isoxazoles, isoxazlines, isoxazolidines, oxazoles, oxazolines, oxazolidines, and oxadiazoles publi shed in 2012
Artemisinin
Authors: Schäfer Bernd 
Published: April 2014

AbstractArtemisinin ist der modernste Wirkstoff gegen Malaria, eine Infektionskrankheit, die den Menschen durch seine gesamte Entwicklungsgeschichte begleitete. Experimentelle Hinweise auf antike Malaria‐Epidemien gelangen durch Vervielfältigung von DNA‐Fragmenten des Erregers mit Hilfe der Polymerasekettenreaktion und dem Abgleich mit dem inzwischen entschlüsselten Genom des Malaria‐Erregers Plasmodium falciparum. Mit der Aufklärung des Lebenszyklus des Erregers eröffnete sich auch ein rationaler Zugang zu effizienten Therapieformen, z. B. mit Schizontiziden, wie Chinin oder Mefloquin, aber auch neuartigen Wirkstoffen, wie Artemisinin.
Von Steinkohlenteer bis zu Krebsmedikamenten
Authors: Plischke Wolfgang , Meier Stephan Michael , Riedl Bernd 
Published: April 2014

AbstractAls Friedrich Bayer und Johann Friedrich Weskott den Grundstein für den heutigen Bayer‐Konzern legten, drehte sich alles um synthetische Farbstoffe. Doch der Steinkohlenteer auf dem diese basierten, bot noch weitere Anwendungsmöglichkeiten: von Pflanzenschutzwirkstoffen über fiebersenkende Arzneimittel bis hin zu Krebsmedikamenten. Anhand beispielhafter chemischer Verbindungen und ihrer Entwicklungsgeschichte – von den Anfängen bis heute – wird die Unternehmenshistorie von Bayer veranschaulicht.
Mit Fliegenantennen Krebs früh erkennen
Authors: Feil Sylvia 
Published: April 2014

AbstractWandelt sich eine Zelle zur Tumorzelle, ändert sich auch ihr Metabolismus. Da viele dieser tumorspezifischen Stoffe kleine Moleküle und damit flüchtig sind, wäre ein nichtinvasiver Krebstest mit der Atemluft vorstellbar.
Experimente nach Wunsch
Authors: Schumacher Elke 
Published: April 2014

AbstractEin Oberstufen‐Chemiekurs und seine Kursleitung haben eine kreative Idee und den Wunsch, ein technisch aufwändiges Schülerexperiment praktisch durchzuführen. Die notwendigen Geräte sind in der Schule nicht verfügbar oder im Kursraum fehlen die nötigen Abzüge. Was kann man tun? Für die Lösung dieses Problems ist das Schülerlabor “Teens' Lab – Xplore Oberstufe” der BASF eine sehr empfehlenswerte Adresse. Hervorragend ausgestattet sowie thematisch und personell flexibel kann es gymnasialen Chemiekursen der Metropolregion Rhein‐Neckar für viele Fälle eine Lösung anbieten. Voraussetzung ist eine gewisse Vorlaufzeit für die Planung der gewünschten Experimente und die Möglichkeit, die erforderlichen Sicherheitsstandards beim Experimentieren mit den Schülern einhalten zu können.
Using soil seed banks to assess temporal patterns of genetic variation in invasive plant populations
Authors: Fennell Mark , Gallagher Tommy , Vintro Luis Leon , Osborne Bruce 
Published: April 2014

AbstractMost research on the genetics of invasive plant species has focused on analyzing spatial differences among existing populations. Using a long‐established Gunnera tinctoria population from Ireland, we evaluated the potential of using plants derived from seeds associated with different soil layers to track genetic variation through time. This species and site were chosen because (1) G. tinctoria produces a large and persistent seed bank; (2) it has been present in this locality, Sraheens, for ~90 years; (3) the soil is largely undisturbed; and (4) the soil's age can be reliably determined radiometrically at different depths. Amplified fragment length polymorphic markers (AFLPs) were used to assess differences in the genetic structure of 75 individuals sampled from both the standing population and from four soil layers, which spanned 18 cm (estimated at ~90 years based on 210Pb and 137Cs dating). While there are difficulties in interpreting such data, including accounting for the effects of selection, seed loss, and seed migration, a clear pattern of lower total allele counts, percentage polymorphic loci, and genetic diversity was observed in deeper soils. The greatest percentage increase in the measured genetic variables occurred prior to the shift from the lag to the exponential range expansion phases and may be of adaptive significance. These findings highlight that seed banks in areas with long‐established invasive populations can contain valuable genetic information relating to invasion processes and as such, should not be overlooked.
A Luminescent Rhenium(I) Metallacycle with Oxygen and Nitrogen Donor Atoms: Photophysical and Theoretical Studies
Authors: Bhattacharya Dibyendu 
Published: April 2014

AbstractA new N,O‐bischelator‐bridged dirhenium(I) metallacycle, [Re2(CO)6(μ‐η4‐mpdo)(μ‐4,4′‐tmdp)] (1, H2mpdo = 2‐methylpyrimidine‐4,6‐diol, 4,4′‐tmdp = 4,4′‐trimethylenedipyridine) has been self‐assembled in a one‐pot reaction in p‐xylene at 140 °C. Compound 1 displays unusual multiple phosphorescence emissions at room temperature; an emission quantum yield of 0.26 ± 0.03 and triexponential decay with an average radiative decay constant of 0.052 μs (λmax = 342 nm) were determined. These results as well as those of DFT/TDDFT calculations confirmed the nature of the emitting states.
Metal‐Free Oxidative Cyclization of o‐Acylphenols for the Construction of 2‐Aminobenzofuran‐3(2H)‐ones
Authors: Yu Hui , Huang Weihua , Zhang Fengling 
Published: April 2014

AbstractAn efficient metal‐free approach to the synthesis of 2‐aminobenzofuran‐3(2H)‐ones has been developed. Using TBHP as an oxidant and I2 (or TBAI) as catalyst, 2‐acylphenols were treated with secondary amines to provide 2‐aminobenzofuran‐3(2H)‐one derivatives in moderate to good yields. A possible reaction pathway for the formation of 2‐dimorpholinobenzofuran‐3(2H)‐one is also discussed herein.
High prevalence of restless legs syndrome among women with multi‐site pain: A population‐based study in Dalarna, Sweden
Authors: Stehlik R. , Ulfberg J. , Hedner J. , Grote L. 
Published: April 2014

AbstractBackgroundThe chronic pain (CP) and chronic multi‐site pain (CMP) condition is a highly prevalent health problem. Several studies have reported a high (31–64%) prevalence of co‐morbid restless legs syndrome (RLS) in patients with fibromyalgia, one specifically defined form of chronic widespread pain. The current study explored the association between CMP and RLS.MethodThe study included 4040 respondents to a postal questionnaire sent to 10,000 women in the age range of 18–64 years and randomly selected from the general population. Complete questionnaire data on type (acute/chronic), degree (mild to severe) and spreading (0–5 body zones) of pain, as well as RLS symptoms (validated questionnaire), were obtained from 3060 subjects. Information on lifestyle, anthropometrics, co‐morbidities and medication was collected.ResultsRLS prevalence increased from 9.6% in subjects with no report of pain to 23,9%, 26.4%, 39.2%, 44.9% and 54.8% in those reporting one, two, three, four and five pain areas, respectively (p < 0.001). Further, RLS prevalence increased from 9.6% (no pain) to 27.9%, 37.9% and 42.4% in subjects with mild, moderate and severe chronic pain (p < 0.001). Multi‐site pain, pain localized in the leg, extended pain duration and co‐morbid psychiatric disorder were all independently associated with a RLS diagnosis in a multiple regression analysis.ConclusionThe prevalence of RLS increased progressively with pain severity and even more sharply with the degree of pain spreading in women recruited from the general population. Both acute and chronic pain was associated with RLS‐related symptoms.
Ethnically based rejection sensitivity and academic achievement: The danger of retracting into one's heritage culture
Authors: Wolfgramm Christine , Morf Carolyn C. , Hannover Bettina 
Published: April 2014

AbstractThis study examined the relation between ethnically based rejection sensitivity and academic achievement in a sample of 936 immigrant students in Germany and Switzerland. The theory of race‐based rejection sensitivity that originated in North America was extended to immigrant students in Europe. The rough political climate against immigrants in Europe makes it probable that immigrant youth face particular difficulties and are affected by ethnically based rejection sensitivity, at least as much as—or even more than—minority youth in the United States. Using a standardized literacy performance test and multilevel analyses, we found that ethnically based rejection sensitivity was negatively related to academic achievement for immigrant students. This relation was partially mediated by a strong contingency of the students' self‐worth on the heritage culture, as well as by a low number of native German or Swiss majority‐group friends. We interpret these processes as immigrant students' efforts to cope with ethnically based rejection sensitivity by retracting into their heritage culture and avoiding majority‐group contact, which unfortunately, however, at the same time also results in lower academic achievement. Copyright © 2014 John Wiley & Sons, Ltd.
Stripping Analysis of As(III) by Means of Screen‐Printed Electrodes Modified with Gold Nanoparticles and Carbon Black Nanocomposite
Authors: Cinti Stefano , Politi Sara , Moscone Danila , Palleschi Giuseppe , Arduini Fabiana 
Published: April 2014

AbstractA novel sensor based on carbon black‐gold nanoparticle nanocomposite modified screen‐printed electrode (CB‐AuNPs/SPE) for the detection of As(III) has been developed. The sensor was prepared modifying the SPE with CB and AuNPs by a drop casting automatable deposition. The As(III) was detected by CB‐AuNPs/SPE using anodic stripping voltammetry, with a high sensitivity (673±6 µA µM−1 cm−2) and reaching a LOD of 0.4 ppb. Finally, CB‐AuNPs/SPE has been applied to As(III) trace analysis in drinking water, obtaining satisfactory recovery values (99±9 %).
Influence of grinding on the nutritive value of peas for ruminants: comparison between in vitro and in situ approaches
Authors: Giger‐Reverdin Sylvie , Maaroufi Chiraze , Chapoutot Patrick , Peyronnet Corinne , Sauvant Daniel 
Published: April 2014

AbstractIn ruminant nutrition, peas are characterized by high protein solubility and degradability, which impair its protein value estimated by the official in situ method. Grinding can be used as a technological treatment of pea seeds to modify their nutritional value. The aim of this study was to compare the in situ method with an in vitro method on the same pea either in a coarse pea flour form (PCF) or in a ground pea fine flour form (PFF) to understand the effect of grinding. Both forms were also reground (GPCF and GPFF). PCF presented a lower rate of in vitro degradation than PFF, and more stable fermentation parameters (pH, ammonia, soluble carbohydrates) even if gas production was higher for the PCF after 48 h of incubation. In situ dry matter and protein degradation were lower for PCF than those for PFF; these differences were more marked than with the in vitro method. Reground peas were very similar to PFF. The values for pea protein digestible in the intestine (PDI) were higher for PCF than those for PFF. This study points out the high sensitivity of the in situ method to grinding. The study needs to be validated by in vivo measurements.
Longitudinal MRI reveals impaired cortical thinning in children and adolescents prenatally exposed to alcohol
Authors: Treit Sarah , Zhou Dongming , Lebel Catherine , Rasmussen Carmen , Andrew Gail , Beaulieu Christian 
Published: April 2014

AbstractBrain imaging studies suggest that cortical thickness decreases during childhood and adolescence, in concert with underlying structural and synaptic changes required for cognitive maturation and regional specialization of function. Abnormalities of this protracted developmental process may provide key insights into the cognitive and behavioral deficits that emerge in individuals with fetal alcohol spectrum disorders (FASD). Several studies have demonstrated cortical thickness differences in children and adolescents who were prenatally exposed to alcohol, though all have been cross sectional, limiting conclusions about cortical development with age. In this study, we analyze serially collected T1‐weighted MRI from 11 children with FASD and 21 controls, scanned twice each ∼2 to 4 years apart. Mixed‐models analysis of cortical thickness measurements revealed age‐by‐group interactions in cortical thinning, with FASD participants undergoing less developmental thinning than controls across many regions of the cortex, particularly in medial frontal and parietal areas. These results provide further longitudinal evidence in humans that prenatal alcohol exposure is associated with altered patterns of brain development that persist during childhood and adolescence. Hum Brain Mapp 35:4892–4903, 2014. © 2014 Wiley Periodicals, Inc.