bluuebunny/crossref_metadata_2025_split huggingface dataset:
Patient-centred management in idiopathic pulmonary fibrosis: similar themes in three communication models
Authors: Wuyts Wim A. , Peccatori Fedro A. , Russell Anne-Marie 
Published: June 2014

The progressive and highly variable course of idiopathic pulmonary fibrosis (IPF) can present patients and their families with various challenges at different points of the disease. Structured communication between the healthcare professional and the patient is vital to ensure the best possible support and treatment for the patient. While research in this area has been limited, an increasing number of studies are emerging that support the role of communication in patients with debilitating and fatal lung diseases.Communication models used in other conditions that share many challenges with IPF, such as cancer, provide important insights for developing specifically designed patient support and communications models in IPF. Three communication models will be described: 1) the patient-centred care model (for oncology); 2) the three pillars of care model (for IPF); and 3) the Brompton model of care (for interstitial lung disease). Themes common to all three models include comprehensive patient education, encouraged patient participation and an accessible healthcare system, all supported by a collaborative provider–patient relationship. The development of effective communication skills is an on-going process and it is recommended to examine communication models used in other chronic diseases.
Management of idiopathic pulmonary fibrosis: selected case reports
Authors: Kreuter Michael , Kardos Peter , Hoffstein Victor 
Published: June 2014

In 2011, revised international guidelines were issued jointly by the American Thoracic Society, the European Respiratory Society, the Japanese Respiratory Society and the Latin American Thoracic Association, which provide a valuable framework for the diagnosis and management of idiopathic pulmonary fibrosis (IPF). However, due to the complexity of IPF, these guidelines may not comprehensively account for the management of individual IPF patients in clinical practice.We describe three patient cases that were presented and discussed during the 2013 AIR: Advancing IPF Research meeting in Nice, France. These cases highlight the heterogeneity in the presentation, history and clinical course of IPF, together with expert insights regarding the diagnosis and management of IPF in the real-life setting.
On stability of functional equations related to quadratic mappings in fuzzy Banach spaces
Authors: Kim Seong Sik , Hussain Nawab , Cho Yeol Je 
Published: June 2014

Abstract
In this paper, we establish the generalized Hyers-Ulam stability problem of radical quadratic functional equations

f
(

x
2

+

y
2

)
=
f
(
x
)
+
f
(
y
)

in fuzzy Banach spaces via the direct and fixed point methods.

MSC:39B72, 39B82, 39B52, 47H09.
Carbonic anhydrase 9 is associated with chemosensitivity and prognosis in breast cancer patients treated with taxane and anthracycline
Authors: Aomatsu Naoki , Yashiro Masakazu , Kashiwagi Shinichiro , Kawajiri Hidemi , Takashima Tsutomu , Ohsawa Masahiko , Wakasa Kenichi , Hirakawa Kosei 
Published: June 2014

Abstract

Background
Neoadjuvant chemotherapy (NAC) is one of the standard care regimens for patients with resectable early-stage breast cancer. It would be advantageous to determine the chemosensitivity of tumors before initiating NAC. One of the parameters potentially compromising such chemosensitivity would be a hypoxic microenvironment of cancer cells. The aim of this study was thus to clarify the correlation between expression of the hypoxic marker carbonic anhydrase-9 (CA9) and chemosensitivity to NAC as well as prognosis of breast cancer patients.

Methods
A total of 102 patients with resectable early-stage breast cancer was treated with NAC consisting of FEC (5-fluorouracil, epirubicin, and cyclophosphamide) followed by weekly paclitaxel before surgery. Core needle biopsy (CNB) specimens and resected tumors were obtained from all patients before and after NAC, respectively. Chemosensitivity to NAC and the prognostic potential of CA9 expression were evaluated by immunohistochemistry.

Results
CA9 positivity was detected in the CNB specimens from 47 (46%) of 102 patients. The CA9 expression in CNB specimens was significantly correlated with pathological response, lymph node metastasis, and lymph-vascular invasion. Multivariate analysis revealed that the CA9 expression in CNB specimens was an independent predictive factor for pathological response. The Kaplan-Meier survival curve revealed a significant negative correlation (p = 0.013) between the disease-free survival (DFS) and the CA 9 expression in resected tissues after NAC. Multivariate regression analyses indicated that the CA9 expression in resected tissues was an independent prognostic factor for DFS.

Conclusions
CA9 expression in CNB specimens is a useful marker for predicting chemosensitivity, and CA9 expression in resected tissue is prognostic of DFS in patients with resectable early-stage breast cancer treated by sequential FEC and weekly paclitaxel prior to resection.
Exploring health-related quality of life in eating disorders by a cross-sectional study and a comprehensive review
Authors: Baiano Monica , Salvo Pierandrea , Righetti Pierluigi , Cereser Lucia , Baldissera Erika , Camponogara Ilenia , Balestrieri Matteo 
Published: June 2014

AbstractBackgroundPeople with eating disorders (ED) often report poor health-related quality of life (HRQoL), which is explicitly correlated to illness’ severity and its effects on cognitive performance. We aimed to analyze health-related quality of life (HRQoL) in subgroups of eating disorder (ED) patients by using the brief version of WHOQoL questionnaire (WHOQoL-BREF) before treatment administration. Moreover, in order to compare our findings with other published data, we carried out a comprehensive review of the literature on HRQoL in ED patients.MethodsOur review was carried out by means of an accurate data mining of PsychInfo and Medline databases and other available sources. In our cross-sectional study, eighty female ED patients (26 with bulimia nervosa, 33 with anorexia nervosa, 7 with binge eating disorder and 14 with ED not otherwise specified) completed the WHOQoL-BREF. HRQoL scores were compared among ED subgroups and clinical information (presence of previous contacts, length of illness, psychiatric comorbidity) was considered in the analysis.ResultsOur review shows that with few exceptions ED patients have a poorer HRQoL than the healthy population of control and sometimes the mental component of HRQoL is the most involved dimension. Moreover, there are no differences in the HRQoL among ED groups, even if AN patients in some studies have a lower HRQoL scores. Furthermore, BED patients have a poorer HRQoL than obese patients who do not have binge episodes. Finally, all treatments were positively correlated with an improvement on general and specific QoL dimensions. In our sample, ED subgroups differed only for Psychological Health HRQoL scores (F = 4.072, df = 3; p = 0.01). No differences were found between inpatients and outpatients, treatment naïve and previously treated patients and patients with or without psychiatric comorbidity. Moreover, HRQoL scores were not correlated to length of illness within each ED subgroup.ConclusionsThe analysis of the literature adds some relevant information on HRQoL in ED and may address the future research toward the exploration of specific questions. One of these may be the prominent role of Psychological Health domain in HRQoL, since our study confirms that this component is able to differentiate eating disorders.
Surface modification and characterization of carbon spheres by grafting polyelectrolyte brushes
Authors: Zhang Qi , Li Houbin , Zhang Pan , Liu Liangliang , He Yuhang , Wang Yali 
Published: June 2014

Abstract
Modified carbon spheres (CSPBs) were obtained by grafting poly(diallyl dimethyl ammonium chloride) (p-DMDAAC) on the surface of carbon spheres (CSs). It can be viewed as a kind of cation spherical polyelectrolyte brushes (CSPBs), which consist of carbon spheres as core and polyelectrolytes as shell. The method of synthesizing carbon spheres was hydrothermal reaction. Before the polyelectrolyte brushes were grafted, azo initiator [4,4′-Azobis(4-cyanovaleric acyl chloride)] was attached to the carbon spheres' surface through hydroxyl groups. CSPBs were characterized by scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FTIR), gel permeation chromatography (GPC), conductivity meter, and system zeta potential. The results showed that compared with carbon spheres, the conductivity and zeta potential on CSPBs increased from 9.98 to 49.24 μS/cm and 11.6 to 42.5 mV, respectively, after the polyelectrolyte brushes were grafted. The colloidal stability in water was enhanced, and at the same time, the average diameter of the CSPBs was found to be 173 nm, and the average molecular weight and grafted density of the grafted polyelectrolyte brushes were 780,138 g/mol and 4.026 × 109/nm2, respectively.
Dynamical behaviors of an SIRI epidemic model with nonlinear incidence and latent period
Authors: Guo Peng , Yang Xinsong , Yang Zhichun 
Published: June 2014

Abstract
In this paper, we study an SIRI epidemic model with nonlinear incidence rate and latent period, namely

k
I
(
t
−
τ
)
S

1
+
α

I
h

(
t
−
τ
)

, which describes the psychological effect of certain serious diseases on the community when the size of the set of infective individuals is getting larger. We first obtain the threshold dynamics on the global stability of the equilibria for the model without latent period, and then we analyze the stability and Hopf bifurcation for the model with the latent period. The results show the influence of nonlinear incidence rate and latent period on the dynamical behaviors of the SIRI model. The examples and its simulations are given to illustrate the obtained results.
A patient-centered network approach to multidisciplinary-guideline development: a process evaluation
Authors: Den Breejen Elvira ME , Hilbink Mirrian AHW , Nelen Willianne LDM , Wiersma Tjerk J , Burgers Jako S , Kremer Jan AM , Hermens Rosella PMG 
Published: June 2014

Abstract

Background
Guideline development and uptake are still suboptimal; they focus on clinical aspects of diseases rather than on improving the integration of care. We used a patient-centered network approach to develop five harmonized guidelines (one multidisciplinary and four monodisciplinary) around clinical pathways in fertility care. We assessed the feasibility of this approach with a detailed process evaluation of the guideline development, professionals’ experiences, and time invested.

Methods
The network structure comprised the centrally located patients and the steering committee; a multidisciplinary guideline development group (gynecologists, physicians, urologists, clinical embryologists, clinical chemists, a medical psychologist, an occupational physician, and two patient representatives); and four monodisciplinary guideline development groups. The guideline development addressed patient-centered, organizational, and medical-technical key questions derived from interviews with patients and professionals. These questions were elaborated and distributed among the groups. We evaluated the project performance, participants’ perceptions of the approach, and the time needed, including time for analysis of secondary sources, interviews with eight key figures, and a written questionnaire survey among 35 participants.

Results
Within 20 months, this approach helped us develop a multidisciplinary guideline for treating infertility and four related monodisciplinary guidelines for general infertility, unexplained infertility, male infertility, and semen analysis. The multidisciplinary guideline included recommendations for the main medical-technical matters and for organizational and patient-centered issues in clinical care pathways. The project was carried out as planned except for minor modifications and three extra consensus meetings. The participants were enthusiastic about the approach, the respect for autonomy, the project coordinator’s role, and patient involvement. Suggestions for improvement included timely communication about guideline formats, the timeline, participants’ responsibilities, and employing a librarian and more support staff. The 35 participants spent 4497 hours in total on this project.

Conclusions
The novel patient-centered network approach is feasible for simultaneously and collaboratively developing a harmonized set of multidisciplinary and monodisciplinary guidelines around clinical care pathways for patients with fertility problems. Further research is needed to compare the efficacy of this approach with more traditional approaches.
Activated and inactivated immune responses in Caenorhabditis elegans against Photorhabdus luminescens TT01
Authors: Sato Kazuki , Yoshiga Toyoshi , Hasegawa Koichi 
Published: June 2014

AbstractThe Gram-negative bacteriumPhotorhabdus luminescenswhich symbiotically associates with the entomopathogenic nematodeHeterorhabditis bacteriophora, has a broad insecticidal and nematicidal activity. The virulence ofP. luminescenstoward the non-mutualistic nematodeCaenorhabditis eleganshas not been described. We showed that when fed onP. luminescens, the intestinal cells ofC. elegansworms become delicate and some crystal-like structure was developed within the intestinal lumen. Next, we examined the requirement of the p38 mitogen-activated protein kinase (MAPK) and insulin/IGF-1 signaling pathway againstP. luminescens. Depletion ofpmk-1by RNAi enhances susceptibility toP. luminescens, and numerous downstream targets regulated by the p38 MAPK pathway were induced when fed onP. luminescens. On the other hand, knockdown ofdaf-16has no effects onC. eleganslifespan, but knockdown ofdaf-2dramatically increased resistance toP. luminescensin adaf-16-dependent manner. We also revealed one of thedaf-2ligandsins-7was induced andins-7deletion mutant survived longer when fed onP. luminescens. These results suggest the p38 MAPK pathway is activated and required for the host defense againstP. luminescens. Insulin/IGF-1 signaling pathway is inactivated byP. luminescensthrough the overexpression of insulin-like gene.
Assessment of near-surface mapping capabilities by airborne transient electromagnetic data — An extensive comparison to conventional borehole data
Authors: Schamper Cyril , Jørgensen Flemming , Auken Esben , Effersø Flemming 
Published: June 2014

A newly developed helicopter transient electromagnetic (TEM) system has the ability to measure very early times within just a few μs after the turn off of the primary current. For such a system, careful calibration and accurate modeling of the electromagnetic (EM) response is critical to get true resistivities of the very shallow geologic layers. We discovered that this leads to resolution of the same level or in some cases even better than what can be obtained from airborne frequency EM systems. This allowed a range of important applications where high and accurate resolution is mandatory, e.g., geotechnical applications such as urban planning, railroad and road investigations, landslides or distribution of raw materials, and assessing aquifer vulnerability. We evaluated the results of a pilot survey covering the Norsminde catchment south of Aarhus, Denmark, where we found that near-surface layers (top 30 m) can be mapped with an accuracy of a few meters in a complicated glacial sedimentary environment. The mapping of the geologic layers was assessed by a detailed analysis in which we developed a general methodology for crosschecking the EM and borehole data. This methodology is general and can easily be adapted to other data types and surveys. After rating the quality of the boreholes based on a list of predefined criteria, we concluded that the EM data matched with about three-quarters of the boreholes located within less than 15 m from the closest EM soundings. The remaining quarter of the boreholes fell into two groups in which half of the boreholes were of very poor quality or had inaccurate coordinates. Only eight of all the boreholes could not be reproduced by the data, and we attributed this to be caused by very strong lateral or vertical geologic variations not resolvable by the TEM technique.
The Important Role of Solvent Reservoir in Self-Assembly of Organic Semiconducting Micro- and Nanowires
Authors: Lambrecht Julia , Saragi Tobat P I 
Published: June 2014

Abstract
We report the crucial role of solvent reservoir in drying under solvent atmosphere method on the growth of self-assembled micro- and nanowires from the solution of organic semiconducting N,N′-diperfluorophenyl-3,4,9,10-perylenetetracarboxylic diimide.
Ion-Selective Marangoni Instability of Oil/Water Interface under a DC Voltage
Authors: Maki Syungo , Yamamoto Ryota , Yamamoto Daigo , Shioi Akihisa 
Published: June 2014

Abstract
Ion-selective Marangoni instability (MI) was studied by electrochemical measurements in order to determine the non-hydrodynamic nonlinear dynamics inherent to the process. An oil-soluble surfactant and calcium ion reacted at the interface, where the reaction products form aggregates. We generated a macroscopic interface where interfacial processes such as reaction and aggregation were synchronized. In this case, a non-hydrodynamic regime was observed before convection: Immediately after applying voltage, we observed an unsynchronized interface and an irregular interfacial flow. However, when the amount of ion transport across the interface exceeded a threshold value, the interface became synchronized, and successive occurrence of MI appeared as a periodical oscillation of interfacial tension. An aggregate of reaction products was considered to proceed homogeneously over the whole synchronized interface. We used a hemispherical droplet shape, and thus an increase in interfacial tension decreased the interfacial area. The interface was then compressed, providing a mechanical work for the desorption of aggregated products. This triggered a hydrodynamic instability.
Application of Cuprous Oxide Nanowires in an Electrochemical Sensor for Ascorbic Acid
Authors: Zhao Jian-wei , Yan Zhong-ke , Qin Li-rong , Feng Xi-ning , Wang Ping 
Published: June 2014

Abstract
A promising electrochemical sensor of ascorbic acid (AA) was constructed based on cuprous oxide nanowires with coarse surface. The sensor exhibited excellent electrocatalytic performance for AA determination in alkaline medium.
Gold-catalyzed Synthesis of 4-(2-Oxoalkoxy)butyl Methanesulfonates via Ring-opening of Tetrahydrofuran
Authors: Huang Wangyong , Xiang Jiannan , He Weimin 
Published: June 2014

Abstract
A variety of terminal alkynes were converted into the corresponding 4-(2-oxoalkoxy)butyl methanesulfonates via a gold-catalyzed intermolecular oxidation reaction using 8-ethylquinoline N-oxide as the oxidant and THF as the solvent. This reaction is proposed to proceed through the ring-opening of THF via an α-oxo gold carbene intermediate.
Book Reviews
Authors: Rand Graham K. 
Published: June 2014

In Book Reviews, we review an extensive and diverse range of books. They cover theory and applications in operations research, statistics, management science, econometrics, mathematics, computers, and information systems. In addition, we include books in other fields that emphasize technical applications. The editor will be pleased to receive an email from those willing to review a book, with an indication of specific areas of interest. If you are aware of a specific book that you would like to review, or that you think should be reviewed, please contact the editor. The following books are reviewed in this issue of Interfaces, 44(3), May–June 2014: Handbook of Global Logistics: Transportation in International Supply Chains, James H. Bookbinder; Decision Making in Service Industries: A Practical Approach, Javier Faulin, Angel A. Juan, Scott E. Grasman, and Michael J. Fry, eds.; Handbook of Operations Research for Homeland Security, Jeffrey W. Herrmann, ed.; Data Mining for Biomarker Discovery, Panos M. Pardalos, Petros Xanthopoulos, and Michalis Zervakis, eds.; Supply Chain Transformation, Practical Roadmap to Best Practice Results, Richard J. Sherman; Supply Chain Network Design: Applying Optimization and Analytics to the Global Supply Chain, Michael Watson, Sara Lewis, Peter Cacioppi, and Jay Jayaraman.
Mortality after total hip replacement surgery
Authors: Berstock J. R. , Beswick A. D. , Lenguerrand E. , Whitehouse M. R. , Blom A. W. 
Published: June 2014

Total hip replacement causes a short-term increase in the risk of mortality. It is important to quantify this and to identify modifiable risk factors so that the risk of post-operative mortality can be minimised. We performed a systematic review and critical evaluation of the current literature on the topic. We identified 32 studies published over the last 10 years which provide either 30-day or 90-day mortality data. We estimate the pooled incidence of mortality during the first 30 and 90 days following hip replacement to be 0.30% (95% CI 0.22 to 0.38) and 0.65% (95% CI 0.50 to 0.81), respectively. We found strong evidence of a temporal trend towards reducing mortality rates despite increasingly co-morbid patients. The risk factors for early mortality most commonly identified are increasing age, male gender and co-morbid conditions, particularly cardiovascular disease. Cardiovascular complications appear to have overtaken fatal pulmonary emboli as the leading cause of death after hip replacement. Cite this article: Bone Joint Res 2014;3:175–82
Removal of Evans Blue and Yellow thiazole dyes from aqueous solution by Mg-Al-CO3 Layered Double Hydroxides as anion-exchanger
Authors: Bouraada Mohamed , Bessaha Hassiba , De MÃ©norval Louis Charles 
Published: June 2014

Mg-Al-CO3 Layered double hydroxide (LDH) was prepared by co-precipitation method at constantÂ pH, and subsequently used to remove Evans Blue (EB) and Yellow thiazole (YT) dyes from aqueous solutions.The obtained material was characterized by powder X-ray diffraction (PXRD), Fourier transform infraredÂ spectroscopy (FTIR), thermal analysis and BET. The kinetic and equilibrium aspects of sorption of the anionicÂ dyes from aqueous solution by Mg-Al-CO3 were investigated in batch mode. The sorption kinetic data wereÂ found to be consistent with the pseudo-second-order model. Data for YT and EB sorption by Mg-Al-CO3 wereÂ fitted better by the Langmuir equation than by the Freundlich equation based on the determinationÂ coefficient values R2. The maximum adsorption capacities of 222.2 mgg-1 for Yellow thiazole and 107.5Â mgg-1 for Evans blue. The thermodynamic parameters including Gibbs free energy (ï„ GÂ°), standard enthalpyÂ change (ï„ HÂ°), and standard entropy change (ï„ SÂ°) for the process were calculated. The negative ï„ GÂ° valueÂ indicates the spontaneity of the removal process.