bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinicopathologic study of the adult rhabdomyoma in the oral and maxillofacial region
Authors: Zhang Lei , Huang Xiao-feng , Li Hui-ling , Xia Shu , Chen Xiu-juan , Chen Sheng , Yang Yan , Ye Chuan-jin , Ni Yan-hong , Zhou Ting 
Published: July 2024

Abstract

Objectives
This study aimed to explore the clinicopathological characteristics of adult rhabdomyoma (A-RM) in the oral and maxillofacial region.
Materials and Methods
We analyzed seven cases of A-RM in the oral and maxillofacial region, focusing on the clinical manifestations, imaging findings, histopathological features, differential diagnosis, treatment, prognosis, and relevant literature review.
Results
The age range of the seven A-RM cases was 4 to 83 years old. Six cases were male and one case was female. Three cases occurred on the floor of the mouth and one case on the tongue. All A-RM cases presented as slow-growing, painless masses. The lesions were lobulated, red-brown nodules with well-defined margins. Histologically, they consisted of densely packed, large, round and polygonal cells with abundant granular eosinophilic cytoplasm. Cross-striations and vacuoles were observed in the cytoplasm. Tumor cells were positive for desmin, myoglobin and myogenin, and some tumor cells were positive for SMA, MyoD1 and S-100 protein. PAS staining was also positive among tumor cells and could be digested by diastase.
Conclusion
Histological examination is the main diagnostic criterion for A-RM. The detection of cross-striations and immunohistochemical expression of myogenic proteins in the cytoplasm are crucial for accurate diagnosis. Radical resection is the main treatment modality with generally favorable prognosis.
A Novel Hybrid Deep Learning IChOA-CNN-LSTM Model for Modality-Enriched and Multilingual Emotion Recognition in Social Media A Novel Hybrid Deep Learning IChOA-CNN-LSTM Model
Authors: Geethanjali R. , VALARMATHI A 
Published: July 2024

Abstract

In the rapidly evolving field of artificial intelligence, the importance of multimodal sentiment analysis has never been more evident, especially amid the ongoing COVID-19 pandemic. Our research addresses the critical imperative to comprehend public sentiment across the multifaceted dimensions of this crisis by integrating data from various modalities such as text, images, audio, and videos sourced from platforms like Twitter. Conventional methods, which primarily focus on text analysis, often fall short in capturing the nuanced intricacies of emotional states, necessitating a more comprehensive approach. To tackle this challenge, our proposed framework introduces a novel hybrid model, IChOA-CNN-LSTM, which leverages Convolutional Neural Networks (CNNs) for precise image feature extraction, Long Short-Term Memory (LSTM) networks for sequential data analysis, and an Improved Chimp Optimization Algorithm (IChOA) for effective feature fusion. Remarkably, our model achieves an impressive accuracy rate of 97.8\%, outperforming existing approaches in the field. Furthermore, by integrating the GeoCoV19 dataset, we enable a comprehensive analysis spanning linguistic and geographical boundaries, thereby enriching our understanding of global pandemic discourse and furnishing indispensable insights for informed decision-making in public health crises. Through this holistic approach and innovative techniques, our research contributes significantly to advancing multimodal sentiment analysis, providing a robust framework for deciphering the complex interplay of emotions amidst unprecedented global challenges like the COVID-19 pandemic
Agricultural Input Subsidies and the Marketing of Agricultural Products
Authors: Panahian payam , Borimnejad Vali , Samari Davood , Nozari Niv 
Published: July 2024

Abstract

The effect of agricultural input subsidies for farmers and other factors on the marketing of agricultural products is investigated in this paper. We first constructed a PLS-SEM; based on that, we designed survey questionnaires for Karaj city in the Alborz Province. The internal model shows that the method of production has the strongest effect on purchase intentions, followed by online purchases and input subsidies. Empirical analysis based on the questionnaire and PLS-SEM shows that the advertising variable has the strongest effect on the economic factors variable, followed by input subsidies and the distribution system. The path relationships between advertising, input subsidies, and the distribution system and economic factors are significant and show that all three variables are relatively strong predictors of economic factors.
The Epidemiological Characteristics of Mycoplasma Pneumoniae Infection and Coinfection among Children in Central China from 2018 to 2023
Authors: Mao Jieyu , Niu Zhili , Liu Mengling , Li Liangyu , Zhang Haiyue , Li Ruiyun , Zhang Pingan , Wu Xiaojun 
Published: July 2024

Abstract

Background
Mycoplasm pneumomiae(M. pneumoniae, MP) is a common cause of reapiratory infections in humans, particularly among children and adolescents. This study investigates the epidemiological characteristics of MP infection among children and its relationship with coinfections to provide guidance for local MP prevention strategies.
Methods
After data screening based on the inclusion and exclusion criteria, a total of 163,058 pediatric patients with Acute Respiratory Tract Infection (ARTI) were enrolled in the study, ranging from January 1, 2018, to December 31, 2023.
Results
From 2018 to 2023, a total of 49,936 cases tested positive for MP, resulting in an overall positive rate of 30.62%. During this period, the annual positive rates were as follows: 45.92%, 32.23%, 22.84%, 16.22%, 16.26%, and 42.93%, respectively. The highest positive rate was observed in autumn (35.13%, P < 0.001). School-aged children exhibited the highest positive rate (40.09%), while infants had the lowest (25.32%, P < 0.001). Furthermore, the positive rate among girls (34.15%) was higher than that among boys (28.01%, P < 0.001). Among patients with MP infection, 14.27% were found to have coinfection with other pathogens, with viral infections accounting for 71.36% and bacterial infections for 28.64%. Notably, infants were more prone to coinfection with multiple pathogens (48.98%, P < 0.001).
Conclusions
MP infection is prevalent in children, with notable seasonal and age-dependent variations in positive rates. Coinfection with other pathogens is common, particularly in infants.
Experimental investigation of the evolution of bed topography in an asymmetrical confluence
Authors: Bombar Gokcen , Cardoso António Heleno 
Published: July 2024

Abstract

This study assessed the time evolution of the bed morphology of six experiments performed by Bombar and Cardoso (2020) on mobile bed confluences. These experiments were characterized by a unique junction angle, a fixed plan layout of the converging channels, constant water discharges and water discharge ratio, and six combinations of the converging sediment transport rates. The end aspect ratio of both channels was sufficiently large to avoid strong wall effects, and the flow was always subcritical and rough turbulent. The bed sediment was a uniform non-ripple forming sand. Detail analysis of the time evolution of the bed morphology showed that balanced fluxes of sediments through the boundaries of the system were a sufficient condition of equilibrium within the range of variables covered by the study. The most important morphological features of the confluence were discussed for several time instants, including those referring to the equilibrium phase. The equilibrium features essentially complied with the morpho-dynamic models reported in the literature for mobile bed confluences, meaning that the time evolution and the end (equilibrium) values of the bed morphologies reported in this paper can be used to validate CFD models thought of as predictive tools of confluence morpho-dynamics. Two experiments are, indeed, ideal for this purpose since they converged to static equilibria, and wrong predictions cannot be attributed to oscillations of the bed, whereas those models may only be able to predict the average, equilibrium values of the bed features of experiments run with sediment supply into the main channel and characterized by the movement of bedforms.
Occurrence and exposure risk assessment of heavy metals and lanthanon in green tea samples cultivated in Hangzhou area
Authors: Wang Shuting , Fan Jicai , Gong Like , Ren Ren , Jin Quan 
Published: July 2024

Abstract

The concentration of heavy metals and lanthanon in 120 green tea samples grown in Hangzhou area were investigated by inductively coupled plasma mass spectrometry (ICP-MS). Except for Hg (69.2%), Sb (98.3%), Se (93.3%) and Sn (94.2%), the detection rate of the other 11 elements were all 100.0%. The mean concentration of heavy metals in tea showed the following order: Mn>Al> Ba> Cu> Ni> Cr> Pb> Sn> Li> V> Se> As> Cd> Sb>Hg. Mn was the highest element found in the tea samples with a concentration ranging from 202.00 to 2010.00 mg/kg and a mean of 836.00 mg/kg. The lowest element was Hg, with a concentration ranging from ND to 0.017 mg/kg and the mean concentration was 0.0033 mg/kg. And all the 120 samples did not exceed the standard limit value of heavy metal. The pollution level of heavy metals indicated that the single pollution index and comprehensive pollution index of green tea produced in Hangzhou area are far below 0.7, which belong to the clean and safety level. Health risk of inhabitant via consuming green tea was conducted and the HI value was 40.75%, less than 100%, which indicates that these chemicals pose no risk to human health in Hangzhou area.
Psychotropic Polypharmacy Impairs Walking Independence in Post-Stroke Patients
Authors: Matsumoto Ayaka , Yoshimura Yoshihiro , Nagano Fumihiko , Shimazu Sayuri , Bise Takahiro , Kido Yoshifumi , Shiraishi Ai , Kuzuhara Aomi , Hamada Takenori , Yoneda Kouki 
Published: July 2024

Abstract

Background Psychotropic drugs are associated with adverse outcomes in older adults. However, evidence on the effect of psychotropic use on walking ability in post-stroke patients is lacking. Aim This study examined the association between psychotropic medication use and walking independence in post-stroke patients. Methods This retrospective cohort study included stroke patients admitted for convalescent rehabilitation at a Japanese hospital between 2020–2022. Psychotropic medications (benzodiazepines, hypnotics, antipsychotics, antidepressants) prescribed at admission were recorded. The primary outcome was walking independence at discharge, defined as a Functional Independence Measure (FIM) walk score ≥ 6. Logistic regression analyses examined the association between the number of psychotropic drugs and walking independence, adjusting for potential confounders. Results Of the 709 patients enrolled, 559 (mean age 75.5 years, 52.8% male) were included in the analysis. At admission, 25.4% of patients used psychotropic drugs. In the adjusted analysis, the number of psychotropic medications was independently associated with lower walking independence at discharge (OR 0.620, 95% CI 0.428–0.897, p = 0.011). Hypnotic use specifically showed a negative impact on walking independence (OR 0.331, 95% CI 0.154–0.708, p = 0.004). However, psychotropic drug use was not significantly associated with improvement in FIM-motor scores. Conclusion Greater psychotropic polypharmacy at admission, particularly with hypnotics, was associated with reduced likelihood of achieving walking independence after stroke rehabilitation. Judicious use of psychotropic medications may be warranted when ambulation is a critical goal for older post-stroke patients.
Experience with stress and the coping process in Chinese nursing and medical students: A constructivist grounded theory study
Authors: Zhang Wei , Cao Zhiyan , Ye Xiaoli , Shen Tong , Zhao Fangfang 
Published: July 2024

Abstract

Background
Nursing and medical students often face a variety of stressors due to the special needs of their majors, such as relatively heavy academic tasks. Their ability to cope with stress affects their health and personal development.
Objectives
To explore the experiences of nursing and medical students coping with stress and construct an interpretive understanding of these experiences from the perspective of nursing and medical.
Design:
A constructivist grounded theory approach.
Settings:
This study included participants from eight departments of a university in Southeastern China.
Participants:
Purposive sampling and snowball sampling were used to select nursing and medical students with experience coping with stress.
Method
Audio-recorded interviews were conducted between May 2020 and January 2021. The data analysis included initial coding, focused coding, and theoretical coding using the constant comparative method and memo writing.
Results
Thirty participants were included in this study. “Physical and mental harmony” was identified as the core category. The following seven categories were conceptualized: enlightening exploration, internal adjustment, seeking social support, emotional support, positive self-awakening, individual degeneration, and asymmetrical resources.
Conclusion
The findings identified that the goal of nursing and medical students in coping with stress is to achieve and maintain physical and mental harmony. It is necessary to help nursing and medical students achieve mental health by understanding and intervening in their stress-coping process, the facilitating factors, obstacles, such as those found in the research, and the context of their occurrence.
WITHDRAWN: Effect Of Using Sterilized Water By Utilizing Non-Thermal Plasma On Hydroponics Growing Of Capucha Lettuce
Authors: Gamal Areej , Shams Mohamed A. , Elkhawas Husin , Hegab Khaled K. 
Published: July 2024

Abstract

Chemical composition and disinfection of fresh Capucha Lettuce are very important. Contamination of irrigation water with pathogenic microbes and its transfer to vegetable plants is considered a major problem facing both internal and external marketing of fresh vegetables crops. Therefore, evaluation of using sterilized water by utilizing non-thermal plasma on hydroponics growing of Capucha Lettuce was aim of this research. Practical experiment was statistically designed, executed and analyzed as factorial experiment in complete randomized block design to evaluate both quantity and quality of growing hydroponics capuchi-lettuce on treated water. Microbial Laboratory test was executed to confirm that there are no pathogenic microbes on the fresh capuchi-lettuce grown on the treated water. Chemical analysis processes were executed to determine chemical composition of the produced Capucha Lettuce. Using non-thermal plasma treated water in hydroponics capuchi-lettuces growing has significant effect on vitamins concentrations, nutrients such as “Potassium, Calcium, magnesium, phosphorus, vitamins (A. C, B4, K)” concentrations, and physical properties capuchi-lettuces. Using non-thermal plasma treated water produce safe fresh capuchi-lettuces and free of pathogenic bacteria.
Preclinical development of a dual targeting bicistronic gene therapy approach for the treatment of wet age-related macular degeneration
Authors: Tam Lawrence CS , Joel Josephine , Stampoulis Dimitris , Little Abigail , Walton Amy , Atkinson-Dell Rebecca , Devine Maya , Hill Jake , Esteve-Rudd Julian , Ellis Scott 
Published: July 2024

Abstract

Age-related macular degeneration (AMD) continues to be a leading cause of severe vision impairment affecting millions worldwide. The late stages of AMD are characterized by outer retinal atrophy (geographic atrophy, GA), or neovascularization associated with subretinal and/or intraretinal exudation (exudative neovascular or ‘wet’ AMD). Intravitreal (IVT) administration of anti-vascular endothelial growth factor (VEGF) therapies has dramatically improved vision preservation for wet AMD (wAMD) patients. However, current Standard of Care (SoC) has significant shortcomings and the benefits of anti-VEGF therapy in the real-world setting fall short of the vision gains observed in randomized clinical trials. This is thought to be attributable to drug burden to patients, lack of therapeutic durability due to progression of underlying macular atrophy and refractility to treatment. Vectorized anti-VEGF therapy has been shown to be effective in reducing drug burden clinically but is unlikely to address the progression of the underlying GA driven by complement-mediated inflammation. Here, we aim to address this unmet need by developing a bicistronic gene therapy vector co-expressing aflibercept and Factor H-like protein 1 (FHL-1) to target the pro-angiogenic and pro-inflammatory environment of wAMD. In vitro assays confirmed the anti-angiogenic and complement inhibitory properties of the bicistronic vector. Recombinant AAV8 (rAAV8)-mediated co-expression was detected for up to 4 weeks following subretinal delivery in wild type (WT) mice. In a mouse laser-induced choroidal neovascularization (CNV) model, subretinal delivery of bicistronic vectors significantly reduced both CNV leakage and lesion. These results demonstrate that a single subretinal administration of bicistronic vector may provide an effective treatment option for wAMD and may also prolong patient’s visual outcomes by preventing the underlying progression of GA.
Association between sleep duration and depression in adults with hypertension: a cross-sectional study
Authors: Chen Lehui , Lv Tian , Wang Xiaoling , Zhao Han , Zhu Qiongbin , Li Jie 
Published: July 2024

Abstract

Background
There is an increasing awareness of sleep duration and depression in hypertension. This study provided a theoretical basis for early screening of depression in patients with hypertension by analyzing the relationship between sleep time and depression in patients with hypertension.
Methods
The data for this study were obtained from the National Health and Nutrition Examination Survey (NHANES) from 2004 to 2015. Depressive symptoms were tested using the Patient Health Questionnaire (PHQ-9), and depression was diagnosed when PHQ-9 total score >10. The association between sleep duration and depression in hypertension was estimated using weighted multivariate logistic regression, and its nonlinearity was examined by restricted cubic spline (RCS) regression. Multivariate logistic regression analysis was used to identify independent risk factors for depression in hypertensive patients, a risk prediction nomogram model was established, and the receiver operating characteristic (ROC) curve was drawn to evaluate its ability to discriminate depression in hypertensive patients.
Results
A total of 8,696 hypertension participants were included in this study. Multivariate logistic regression showed that an increment of sleep duration was strongly associated with depression in hypertension (OR = 0.772, 95%CI = (0.705, 0.883). The RCS curve showed L-shaped relationships between sleep duration and depressive risk in hypertension. The nomogram model showed a favorable discriminatory power with an area under the curve (AUC) of 73.4%. Sleep duration at 7.22 hour might be most beneficial for the mental health of patients with hypertension.
Conclusion
Our study demonstrated the relationship between sleep duration and depression in patients with hypertension, Effective interventions for sleep disorders in patient with hypertension are needed for preventing depression.
Nomogram Model Establishment for Short-Term Survival Prediction in Hypothyroidism Patients with Heart Failure Based on the MIMIC-IV Database
Authors: Lou Wenfeng , Guo Yikun , Hu Tielin , Yan Zewen , Qi Shuo , Ding Zhiguo 
Published: July 2024

Abstract

The objective of this study was to develop an efficient nomogram model for predicting short-term survival in hypothyroidism patients with heart failure. Methods: Retrospective data was extracted from the Medical Information Mart for Intensive Care (MIMIC-IV) open-source clinical database. Patients diagnosed with hypothyroidism and heart failure upon admission were randomly assigned to the training and testing sets. Independent prognostic factors were determined through univariate and multivariate Cox regression analysis. The correlation between variables was assessed using the variance inflation factor. A nomogram model was constructed based on the identified prognostic factors, and risk scores were generated. The model's performance was assessed using the C-index, receiver operating characteristic (ROC) curve, calibration curve, and decision curve analysis (DCA). Result: A total of 656 hypothyroidism patients with heart failure were included in the study. Age, Sequential Organ Failure Assessment (SOFA) score, blood glucose (Glu), blood urea nitrogen (BUN), creatinine (Cr), respiratory rate (RR), and Charlson Comorbidity Index (CCI) score were identified as independent risk factors for patient mortality and were incorporated into the final model. The C-index for the training and testing sets was 0.763 and 0.721, respectively, indicating good accuracy of the model. Evaluation of the ROC curve, calibration curve, and decision curve further confirmed the model's robust and reliable predictive performance. Conclusion: In conclusion, our study successfully developed a convenient and effective nomogram model for predicting short-term mortality in hypothyroidism patients with heart failure. We identified several independent risk factors, including age, respiratory rate, serum creatinine, blood glucose levels, etc. These findings have implications for developing individualized therapeutic plans, enhancing patient management and follow-up, and ultimately improving disease outcomes.