bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Structure and Superconductivity in New Nb‐Based Cuprates (Nb,Ti,Cu)Sr2EuCu2Oz.
Authors: Lee H. K. , Kim Y. I. 
Published: October 2015

AbstractPolycrystalline samples of (Nb1‐xCux)Sr2EuCu2Oz (0 ≤ x ≤ 0.5) and (Nb0.9‐xTi0.1Cux) Sr2EuCu2Oz (0 ≤ x ≤ 0.4) are prepared by calcination of stoichiometric amounts of the metal oxides in air (1010 °C, 7‐10 h) followed by sintering in O2 (1.
ChemInform Abstract: FeV2S4 as a High Capacity Electrode Material for Sodium‐Ion Batteries.
Authors: Krengel Markus , Adelhelm Philipp , Klein Franziska , Bensch Wolfgang 
Published: October 2015

AbstractThe title compound is synthesized by solid state reaction of a stoichiometric mixture of the elements (quartz tube, 1123 K, 5 d).
ChemInform Abstract: Improving Photocatalytic Water Reduction Activity for In2TiO5 by Loading Metal Cocatalysts.
Authors: Song Kai , Yang Jia , Sun Yu , Wang Ziyao , Wang Ling , Cong Rihong , Yang Tao 
Published: October 2015

AbstractIn2TiO5 is prepared by firing stoichiometric amounts of TiO2 and In2O3 in air (1050 °C, 15 h).
ChemInform Abstract: A Thermoelectric Zintl Phase Na2+xGa2+xSn4‐x with Disordered Na Atoms in Helical Tunnels.
Authors: Yamada Takahiro , Yamane Hisanori , Nagai Hideaki 
Published: October 2015

AbstractPolycrystalline Na2+xGa2+xSn4‐x (x = ‐0.04—0.3) are prepared by first heating Na and Sn (BN crucible in steel container, 873 K, 2 h) before Ga is added to the cooled mixture and heated again (BN crucible, 1.
ChemInform Abstract: Crystal and Electronic Structures of Two New Iron Selenides: Ba4Fe3Se10 and BaFe2Se4.
Authors: Berthebaud David , Perez Olivier , Tobola Janusz , Pelloquin Denis , Maignan Antoine 
Published: October 2015

AbstractBa4Fe3Se10 (I) and BaFe2Se4 (II) are prepared from stoichiometric amounts of the elements (evacuated silica tubes, 700 °C, 2 d).
ChemInform Abstract: Microwave‐Assisted Solvothermal Synthesis of Three Polymorphs of LiCoPO4 and Their Electrochemical Properties.
Authors: Kreder Karl J. III , Assat Gaurav , Manthiram Arumugam 
Published: October 2015

AbstractThree orthorhombic polymorphs of LiCoPO4 belonging to the space groups Pnma, Pn21a, and Cmcm are synthesized by a microwave‐assisted solvothermal method from mixtures of LiOH, Co(OAc)2, and H3PO4 using tetra‐ethylene glycol as the solvent (microwave vessel, 260 °C, 30 min).
ChemInform Abstract: Ba2Cu2Te2P2O13: A New Telluro‐Phosphate with S=1/2 Heisenberg Chain.
Authors: Xia Mingjun , Shen Shipeng , Lu Jun , Sun Young , Li R. K. 
Published: October 2015

AbstractSingle crystals of Ba2Cu2Te2P2O13 are grown by firing BaCO3, TeO2, CuO, and NH4H2PO4 in the molar ratio of 3:4:3:2, resp.
ChemInform Abstract: Synthesis and Crystal Structure of Bi6 (Bi0.5Cu0.5)V2O15+y.
Authors: Gupta Akanksha , Uma S. 
Published: October 2015

AbstractPolycrystalline Bi6 (Bi0.5Cu0.5)V2O15+y is prepared by heating a 3:1:1 molar mixture of Bi2O3, CuO, and V2O5 (750 °C, 12 h), and single crystals are grown from the polycrystalline product (Pt crucible, 1000 °C; cooling to 850 °C °C with a rate of 2 °C/h and to 750 °C with a rate of 5 °C/h).
ChemInform Abstract: Iron‐Catalyzed Oxidative C—C and C—O Coupling of Halophenols to α‐Substituted β‐Keto Esters.
Authors: Regev Almog , Shalit Hadas , Pappo Doron 
Published: October 2015

AbstractThe chemoselectivity of these reactions is determined by both the electronic and steric properties of the two coupling partners.
ChemInform Abstract: N,N′‐Dioxide/Zinc Bis(trifluoromethylsulfonyl)imide Complex Catalyzed Enantioselective Diels—Alder Reaction of Cyclopentadiene with Alkynones.
Authors: Kang Tengfei , Wang Zhen , Lin Lili , Liao Yuting , Zhou Yuhang , Liu Xiaohua , Feng Xiaoming 
Published: October 2015

AbstractThe title process affords 2‐acyl substituted norbornadienes in moderate to high yields with good enantiomeric excess up to 95%.
ChemInform Abstract: Dual Hypervalent Iodine(III) Reagents and Photoredox Catalysis Enable Decarboxylative Ynonylation under Mild Conditions.
Authors: Huang Hanchu , Zhang Guojin , Chen Yiyun 
Published: October 2015

AbstractThe first hypervalent iodine reagent (HIR)/photoredox dual catalysis to form radicals from α‐ketoacids, followed by an unprecedented acyl radical addition to HIR‐bound alkynes is presented.
ChemInform Abstract: Remote Hydroxylation Through Radical Translocation and Polar Crossover.
Authors: Hollister Kyle A. , Conner Elizabeth S. , Spell Mark L. , Deveaux Kristina , Maneval Lea , Beal Michael W. , Ragains Justin R. 
Published: October 2015

AbstractThe site‐selective replacement of relatively inert aliphatic C—H bonds with the hydroxy group is facilitated by employing the photocatalyst together with sulfonate esters and sulfonamides and involves a radical translocation, oxidation to carbocation, and nucleophilic trapping with H2O under mild reaction conditions.
ChemInform Abstract: Reversible Substrate Activation and Catalysis at an Intact Metal—Metal Bond Using a Redox‐Active Supporting Ligand.
Authors: Steiman Talia J. , Uyeda Christopher 
Published: October 2015

AbstractBased on a dinuclear mode of activation, a Ni2(naphthyridine‐diimine) complex catalyzes the high‐yielding hydrosilylation of alkenes, dienes, alkynes, aldehydes, ketones, enones, and amides.
ChemInform Abstract: Nickel Promoted Switchable Hydroheteroarylation of Cyclodienes via C—H Bond Activation of Heteroarenes.
Authors: Lee Wei‐Chih , Shih Wei‐Chin , Wang Ting‐Hsuan , Liu Yuhua , Yap Glenn P.A. , Ong Tiow‐Gan 
Published: October 2015

AbstractBy simply changing the ligand, the regioselectivity of the title reaction can be switched.
ChemInform Abstract: Iron‐Catalyzed C(sp2)—H and C(sp3)—H Methylations of Amides and Anilides.
Authors: Graczyk Karolina , Haven Tobias , Ackermann Lutz 
Published: October 2015

AbstractThe use of easily accessible modular TAM auxiliaries allow the site‐, chemo‐, and diastereoselective C—H methylation of (hetero)benzamides, anilides, alkenes, and even alkanes.
ChemInform Abstract: Chemoselective Synthesis of Biheterocyclic Skeletons Tetrahydro‐1H‐pyrrolo[1,2‐c]imidazole and Tetrahydropyrrolo[1,2‐c]thiazole Derivatives via Multicomponent Self‐Sorting Domino Strategy.
Authors: Cai Qun , Jia Feng‐Cheng , Li Deng‐Kui , Xu Cheng , Ding Ke‐Rong , Wu An‐Xin 
Published: October 2015

AbstractA convenient and efficient approach for the synthesis of the title imidazole and thiazole derivatives from readily available starting materials by simple solvent‐switching is demonstrated.
ChemInform Abstract: Palladium‐Catalyzed Chemoselective Synthesis of Indane‐1,3‐dione Derivatives via tert‐Butyl Isocyanide Insertion.
Authors: Duan Huaqing , Chen Zhong , Han Li , Feng Yulin , Zhu Yongming , Yang Shilin 
Published: October 2015

AbstractStarting from various aryl and alkyl substituted acetophenone or 3‐arylacetylacetone derivatives numerous indane‐1,3‐diones are prepared either protected as tert‐butyl imine derivatives or in their unprotected form.
ChemInform Abstract: Direct C—N Bond Cleavage of N‐Vinyl or N‐Allyl Arylamines: A Metal‐Free Strategy for N‐Devinylation and N‐Deallylation.
Authors: Balgotra Shilpi , Venkateswarlu Vunnam , Vishwakarma Ram A. , Sawant Sanghapal D. 
Published: October 2015

AbstractTreatment of N‐vinyl and N‐allyl arylamines with TFA/Oxone results in devinylation or deallylation, N‐trifluoroacetylation, and ortho‐hydroxylation to give the corresponding o‐aminophenyl derivatives (III).
ChemInform Abstract: Chemoselective Reductive Amination of Carbonyl Compounds for the Synthesis of Tertiary Amines Using SnCl2·2H2O/PMHS/MeOH.
Authors: Nayal Onkar S. , Bhatt Vinod , Sharma Sushila , Kumar Neeraj 
Published: October 2015

AbstractCarbonyl compounds are aminated by aromatic amines to give tertiary and secondary amines chemoselectively.
ChemInform Abstract: Copper‐Catalyzed Regio‐ and Stereoselective Ring‐Opening of Cyclic Sulfamidates with Grignard Reagents Assisted by Lithium Chloride.
Authors: Arigala Pitchaiah , Sadu Venkata S. , Hwang In‐Taek , Hwang Jin‐Soo , Kim Chul‐Ung , Lee Kee‐In 
Published: October 2015

AbstractThe title reaction provides α‐branched benzylamine derivatives in high yields.
ChemInform Abstract: 4‐CH3CONH‐TEMPO/Peracetic Acid System for a Shortened Electron‐Transfer‐Cycle‐Controlled Oxidation of Secondary Alcohols.
Authors: Zhang Shufang , Miao Chengxia , Xia Chungu , Sun Wei 
Published: October 2015

AbstractThe reagent system allows the oxidation of a wide variety of secondary alcohols into ketones under mild, metal‐free conditions.
ChemInform Abstract: General Approach to a Spiro Indole‐3,1′‐naphthalene Tetracyclic System: Stereoselective Pseudo Four‐Component Reaction of Isatins and Cyclic Ketones with Two Molecules of Malononitrile.
Authors: Elinson M. N. , Vereshchagin A. N. , Nasybullin R. F. , Bobrovsky S. I. , Ilovaisky A. I. , Merkulova V. M. , Bushmarinov I. S. , Egorov M. P. 
Published: October 2015

AbstractA base‐promoted multicomponent reaction of isatins, cyclic ketones, and malononitrile affords tetracyclic spirooxindoles stereoselectively.
ChemInform Abstract: A Mild and Efficient CH2‐Extrusion Reaction for the Enantiospecific Synthesis of Highly Configurationally Stable Troeger Bases.
Authors: Pujari Sandip A. , Besnard Celine , Buergi Thomas , Lacour Jerome 
Published: October 2015

AbstractOxidation of ethano‐Troeger bases (I) and (III) with DDQ in wet nitromethane results in a highly enantiospecific methylene extrusion to afford ring contracted products (II) and (IV) which are significantly more configurationally stable than regular Troeger bases.
ChemInform Abstract: Synthesis of Benzofurans via Tandem Rhodium‐Catalyzed C(sp3)—H Insertion and Copper‐Catalyzed Dehydrogenation.
Authors: Li Lin , Xia Xiao‐Han , Wang Yong , Bora Pranjal P. , Kang Qiang 
Published: October 2015

AbstractBenzofurane derivatives are prepared from triazole substrates via a tandem insertion/aerobic oxidation sequence.
ChemInform Abstract: Pd(OAc)2/AgOAc Catalytic System Based Bidentate Ligand Directed Regiocontrolled C—H Arylation and Alkylation of the C‐3 Position of Thiophene‐ and Furan‐2‐carboxamides.
Authors: Padmavathi Rayavarapu , Sankar Rathinam , Gopalakrishnan Bojan , Parella Ramarao , Babu Srinivasarao Arulananda 
Published: October 2015

AbstractThe title procedure is investigated for various educts bearing different ligands at the amide nitrogen.
ChemInform Abstract: Heterogeneous Fe‐MIL‐101 Catalysts for Efficient One‐Pot Four‐Component Coupling Synthesis of Highly Substituted Pyrroles.
Authors: Tang Jia , Yang Mu , Yang Ming , Wang Jingjing , Dong Wenjun , Wang Ge 
Published: October 2015

AbstractThe entitled catalyst exhibits an higher activity than Fe‐MIL‐88B and Fe‐MIL‐53 due to its higher surface area and larger pore size.
ChemInform Abstract: Gold(I)‐Catalyzed Tandem Reaction of γ‐Amino‐Substituted Propargylic Esters to Pyrrolines and Its Application in the Formal Synthesis of (.+‐.)‐Aphanorphine.
Authors: Wang Zhengshen , Zheng Huaiji , Yang Juan , Xie Xingang , She Xuegong 
Published: October 2015

AbstractA wide range of pyrrolines are prepared through a gold(I)‐catalyzed tandem 1,3‐acyloxy rearrangement/intramolecular azacyclization reaction of propargylic esters.
ChemInform Abstract: Unified Approach to Isoindolinones and THIQs via Lewis Acid Catalyzed Domino Mukaiyama—Mannich Lactamization/Alkylations: Application in the Synthesis of (.+‐.)‐Homolaudanosine.
Authors: Dhanasekaran Sivasankaran , Kayet Anirban , Suneja Arun , Bisai Vishnumaya , Singh Vinod K. 
Published: October 2015

AbstractElectron‐deficient amines, e.g. Tos‐NH2 and Cbz‐NH2, do not react in this procedure.
ChemInform Abstract: Friedel—Crafts Alkylation of Indoles in Deep Eutectic Solvent.
Authors: Kumar Atul , Shukla Ratnakar Dutt , Yadav Dhiraj , Gupta Lalit Prakash 
Published: October 2015

AbstractIn addition to the Lewis‐acid free Friedel—Crafts alkylation of indoles with isatin, acenaphthylene‐1,2‐dione and aceanthrylene‐1,2‐dione are transformed.
ChemInform Abstract: Copper/β‐Diketone‐Catalyzed N‐Arylation of Carbazoles.
Authors: Chen Fei , Liu Ning , Ji Enhui , Dai Bin 
Published: October 2015

AbstractThe developed method allows for the efficient transformation of carbazoles equipped with no or electron‐donating groups while electron‐withdrawing groups lead to lower product yields.
ChemInform Abstract: A Simple and Efficient 2N2O‐Cu(II) Complex as a Catalyst for N‐Arylation of Imidazoles in Water.
Authors: Liu Yashuai , Gu Ningning , Liu Ping , Xie Jianwei , Dai Bin , Liu Yan 
Published: October 2015

AbstractFour inexpensive and air‐ and moisture‐stable 2N2O—Cu complexes are synthesized, one of them shows good catalytic activity for the N‐arylation of imidazoles in water.
ChemInform Abstract: Increased SBA‐15‐SO3H Catalytic Activity Through Hydrophilic/Hydrophobic Fluoroalkyl‐Chained Alcohols (RFOH/SBA‐15—Pr‐SO3H).
Authors: Rostamnia Sadegh , Doustkhah Esmail 
Published: October 2015

AbstractThe catalyst is recyclable and reusable at least 8 times.
ChemInform Abstract: Cu/Pd‐Catalyzed, Three‐Component Click Reaction of Azide, Alkyne, and Aryl Halide: One‐Pot Strategy Toward Trisubstituted Triazoles.
Authors: Wei Fang , Li Haoyu , Song Chuanling , Ma Yudao , Zhou Ling , Tung Chen‐Ho , Xu Zhenghu 
Published: October 2015

AbstractThis is a general method for the synthesis of triazoles with various different substituents.
ChemInform Abstract: PEG‐Assisted Two‐Component Approach for the Facile Synthesis of 5‐Aryl‐1,2,4‐triazolidine‐3‐thiones under Catalyst‐Free Conditions.
Authors: Ramesh Rathinam , Lalitha Appaswami 
Published: October 2015

AbstractThe title synthesis is conducted under very convenient neutral reaction conditions.
ChemInform Abstract: Application of a Functionalized Mesoporous Silica Catalyst to the Synthesis of Tetrazoles.
Authors: Najafi Chermahini Alireza , Khani Omran Masoud , Dabbagh Hossein A. , Mohammadnezhad Gholamhossein , Teimouri Abbas 
Published: October 2015

AbstractA new strategy for the formation of a wide range of substituted tetrazoles (II) by using modified MCM‐41 via the [3 + 2] cycloaddition reaction of nitriles and sodium azide is presented.
ChemInform Abstract: Tris‐hydroxymethylaminomethane (THAM): A Novel Organocatalyst for a Environmentally Benign Synthesis of Medicinally Important Tetrahydrobenzo[b]pyrans and Pyran‐Annulated Heterocycles.
Authors: Pandit Kapil S. , Chavan Pramod V. , Desai Uday V. , Kulkarni Makarand A. , Wadgaonkar Prakash P. 
Published: October 2015

AbstractThe entitled organocatalyst is non‐toxic, cheap, bio‐degradable and easy to handle, and is used in the synthesis of pyran‐annulated heterocycles for the first time.
ChemInform Abstract: Divergent Method to trans‐5‐Hydroxy‐6‐alkynyl/alkenyl‐2‐piperidinones: Syntheses of (—)‐Epiquinamide and (+)‐Swainsonine.
Authors: Si Chang‐Mei , Mao Zhuo‐Ya , Dong Han‐Qing , Du Zhen‐Ting , Wei Bang‐Guo , Lin Guo‐Qiang 
Published: October 2015

AbstractA convenient, one‐pot cascade for the reaction of a γ‐methoxycarbonyl aldimine with alkynyl‐ and alkenyl Grignard reagents to give piperidinones is presented.
ChemInform Abstract: Synthesis of Tetraarylpyridines by Chemo‐Selective Suzuki—Miyaura Reactions of 3,5‐Dibromo‐2,6‐dichloropyridine.
Authors: Reimann Sebastian , Parpart Silvio , Ehlers Peter , Sharif Muhammad , Spannenberg Anke , Langer Peter 
Published: October 2015

AbstractConditions for the chemoselective preparation of 3,5‐diaryl‐2,6‐dichloropyridines which are further transformed to 2,3,5,6‐tetraarylpyridines bearing two different aryl groups are described.
ChemInform Abstract: Asymmetric Organocatalytic Michael Addition/Aza‐Cyclization Coupled with Sequential Michael Addition for Synthesizing Densely Polycyclic‐Fused Dihydroquinolines.
Authors: Yu Mirim , Kim Sung‐Gon 
Published: October 2015

AbstractThe title reaction sequence provides the products with excellent dia‐ and enantioselectivity.
ChemInform Abstract: Iron/Acetic Acid Mediated Synthesis of 6,7‐Dihydrodibenzo[b,j][1,7]phenanthroline Derivatives via Intramolecular Reductive Cyclization.
Authors: Rajawinslin R. R. , Ichake Sachin S. , Kavala Veerababurao , Gawande Sachin D. , Huang Yi‐Hsiang , Kuo Chun‐Wei , Yao Ching‐Fa 
Published: October 2015

AbstractThe scalable reaction procedure tolerates various substituents.
ChemInform Abstract: Molecular Iodine Catalyzed Domino Cyclization in Aqueous Medium: A Simple and Efficient Synthetic Route to 1,4‐Dihydropyridazines.
Authors: Siddiqui I. R. , Rahila Rahila , Rai Pragati , Sagir Hozeyfa , Waseem Malik A. 
Published: October 2015

AbstractEnvironmentally friendly reaction conditions with an inexpensive and recoverable catalyst, avoidance of toxic reagents and volatile solvents, operational simplicity, and the compatibility with various functional groups are the advantages of the present procedure.
ChemInform Abstract: Molybdate Sulfuric Acid (MSA): An Efficient Solid Acid Catalyst for the Synthesis of Diversely Functionalized Fused Imidazo[1,2‐a]pyrimidines under Solvent‐Free Conditions.
Authors: Shinde Vijay Vilas , Jeong Yeon Tae 
Published: October 2015

AbstractThe entitled compounds (IV) are formed in an one‐pot multi‐component, green, and efficient protocol.
ChemInform Abstract: Radical‐Induced Metal‐Free Alkynylation of Aldehydes by Direct C—H Activation
Authors: Liu Xuesong , Yu Linqian , Luo Mupeng , Zhu Jidong , Wei Wanguo 
Published: October 2015

Abstractusing a hypervalent iodine alkynylation reagent for the introduction of the triple bond under metal‐free reaction conditions
ChemInform Abstract: Synthesis of Chiral Nβ‐Protected Amino Diselenides from the Corresponding Amino Alkyl Iodides Using NaBH2Se3 as a Selenating Reagent and Their Conversion to Seleninic Acids.
Authors: Panguluri Nageswara Rao , Panduranga Veladi , Prabhu Girish , Vishwanatha T. M. , Sureshbabu Vommina V. 
Published: October 2015

AbstractThe protocol is based on the in‐situ‐formation of NaBH2Se3 and operates efficiently using various amino alkyl iodides, including N‐Boc, Cbz, and Fmoc protected ones as well as alkyl and aryl substituted ones and amino acid derived compounds.
ChemInform Abstract: Kaempulchraols I—O: New Isopimarane Diterpenoids from Kaempferia pulchra rhizomes Collected in Myanmar and Their Antiproliferative Activity.
Authors: Win Nwet Nwet , Ito Takuya , Aimaiti Simayijiang , Kodama Takeshi , Imagawa Hiroshi , Ngwe Hla , Asakawa Yoshinori , Abe Ikuro , Morita Hiroyuki 
Published: October 2015

AbstractThe isolation and structure elucidation of kaempulchraols I (Ia), J (Ib), K (IIa), L (IIb), M (III), N (IVa), and O (IVb) is described.
ChemInform Abstract: Epimeric Excolides from the Stems of Excoecaria agallocha and Structural Revision of Rhizophorin A.
Authors: Annam S. CH. V. Appa Rao , Ankireddy Madhu , Sura Madhu Babu , Ponnapalli Mangala Gowri , Sarma Akella V. S. , Jeelani Basha S. 
Published: October 2015

AbstractExcolide A (I), 11‐epi‐excolide A (II), 11,13‐di‐epi‐excolide A (III), and excolide B (IV) are the first examples of a new class of secolabdanoids from the title species.
ChemInform Abstract: Formal Synthesis of Sarain A: Intramolecular Cycloaddition of an Eight‐Membered Cyclic Nitrone to Construct the 2‐Azabicyclo[3.3.1]nonane Framework.
Authors: Higo Takuya , Ukegawa Tomoya , Yokoshima Satoshi , Fukuyama Tohru 
Published: October 2015

AbstractA synthetic route to the tetracyclic skeleton of sarain A is developed, featuring an intramolecular cycloaddition of an eight‐membered cyclic nitrone to construct the 2‐azabicyclo[3.3.1]nonane framework and an iodoamidation reaction to form the pyrrolidine ring.
ChemInform Abstract: Six New Polyacetylenic Alcohols from the Marine Sponges Petrosia sp. and Halichondria sp.
Authors: Gabriel Adeyemi Francis , Li Zhen , Kusuda Ryouhei , Tanaka Chiaki , Miyamoto Tomofumi Miyamoto Tomofumi 
Published: October 2015

AbstractSix new polyacetylenic alcohols, termed strongylotriols A (Ia) and B (Ib), isopellynol A (II), pellynols J (IIIa), K (IIIb), and L (IV) are isolated from the marine sponges Petrosia sp., and Halichondria sp.
ChemInform Abstract: Terfestatins B and C, New p‐Terphenyl Glycosides Produced by Streptomyces sp. RM‐5—8.
Authors: Thorson Jon S. , et al.  
Published: October 2015

AbstractTerfestatins B (I) and C (II) as well as indole derivative (III) bear a novel 4‐deoxy‐α‐L‐threo‐hex‐4‐enopyranuronate residue.
Stereoselective Degradation of alpha‐Cypermethrin and Its Enantiomers in Rat Liver Microsomes
Authors: Yan Jin , Zhang Ping , Wang Xinru , Xu Meiqi , Wang Yao , Zhou Zhiqiang , Zhu Wentao 
Published: October 2015

AbstractAlpha‐cypermethrin (α‐CP), [(RS)‐a‐cyano‐3‐phenoxy benzyl (1RS)‐cis‐3‐(2, 2‐dichlorovinyl)‐2, 2‐dimethylcyclopropanecarboxylate], comprises a diastereoisomer pair of cypermethrin, which are (+)‐(1R‐cis‐αS)–CP (insecticidal) and (−)‐(1S‐cis‐αR)–CP (inactive). In this experiment, the stereoselective degradation of α‐CP was investigated in rat liver microsomes by high‐performance liquid chromatography (HPLC) with a cellulose‐tris‐ (3, 5‐dimethylphenylcarbamate)‐based chiral stationary phase. The results revealed that the degradation of (−)‐(1S‐cis‐αR)‐CP was much faster than (+)‐(1R‐cis‐αS)‐CP both in enantiomer monomers and rac‐α‐CP. As for the enzyme kinetic parameters, there were some variances between rac‐α‐CP and the enantiomer monomers. In rac‐α‐CP, the Vmax and CLint of (+)‐(1R‐cis‐αS)–CP (5105.22 ± 326.26 nM/min/mg protein and 189.64 mL/min/mg protein) were about one‐half of those of (−)‐(1S‐cis‐αR)–CP (9308.57 ± 772.24 nM/min/mg protein and 352.19 mL/min/mg protein), while the Km of the two α‐CP enantiomers were similar. However, in the enantiomer monomers of α‐CP, the Vmax and Km of (+)‐(1R‐cis‐αS) ‐CP were 2‐fold and 5‐fold of (−)‐(1S‐cis‐αR)‐CP, respectively, which showed a significant difference with rac‐α‐CP. The CLint of (+)‐(1R‐cis‐αS)–CP (140.97 mL/min/mg protein) was still about one‐half of (−)‐(1S‐cis‐αR)–CP (325.72 mL/min/mg protein) in enantiomer monomers. The interaction of enantiomers of α‐CP in rat liver microsomes was researched and the results showed that there were different interactions between the IC50 of (−)‐ to (+)‐(1R‐cis‐αS)‐CP and (+)‐ to (−)‐(1S‐cis‐αR)‐CP(IC50(−)/(+) / IC50(+)/(−) = 0.61). Chirality 28:58–64, 2016. © 2015 Wiley Periodicals, Inc.
Elimination du zinc par les cosses de petits pois (Pisum sativum) et les feuilles de lierre (Hedera helix L) Elimination of zinc by peapods (Pisum sativum) and ivy leaves (Hedera helix L)
Authors: Menia Sabah , Azzouz Noureddine , El Maleh Samuel 
Published: October 2015

RésuméLa pollution des eaux souterraines et de surface par les métaux lourds constitue un grand problème pour l'environnement ; de ce fait il s'avère nécessaire de pouvoir éliminer ces substances toxiques. Il existe de nombreuses méthodes qui permettent d'éliminer ces dernières, telles que l'adsorption, la précipitation chimique et la filtration sur membrane.Dans notre étude, le zinc a été adsorbé sur les cosses de petits pois et les feuilles de lierre. Un temps de réaction de 30 minutes a été obtenu pour les deux adsorbants ; ainsi qu'un pH optimal égal à 4 pour les feuilles de lierre et à 5 pour les cosses de petits pois. Les résultats obtenus montrent également que les isothermes d'adsorption sont de type I.
Robust estimation for longitudinal data with informative observation times
Authors: Liu Kin‐yat , Zhao Xingqiu 
Published: October 2015

AbstractIn this paper we focus on regression analysis of irregularly observed longitudinal data that often occur in medical follow‐up studies and observational investigations. The analysis of these data involves two processes. One is the underlying longitudinal response process of interest and the other is the observation process that controls observation times. Most of the existing methods, however, rely on some restrictive models or assumptions such as the Poisson assumption. For this we propose a class of more flexible joint models and a robust estimation approach for regression analysis of longitudinal data with related observation times. The asymptotic properties of the proposed estimators are established and a model checking procedure is also presented. The numerical studies indicate that the proposed methods work well for practical situations. The Canadian Journal of Statistics 43: 519–533; 2015 © 2015 Statistical Society of Canada