bluuebunny/crossref_metadata_2025_split huggingface dataset:
Supplemental dietaryl-arginine attenuates intestinal mucosal disruption during a coccidial vaccine challenge in broiler chickens
Authors: Tan Jianzhuang , Applegate Todd J. , Liu Shasha , Guo Yuming , Eicher Susan D. 
Published: September 2014

The present study investigated the effects of dietary arginine (Arg) supplementation on intestinal structure and functionality in broiler chickens subjected to coccidial challenge. The present study was a randomised complete block design employing a 3 × 2 factorial arrangement (n8) with three dietary concentrations of Arg (11·1, 13·3 and 20·2 g/kg) with or without coccidial vaccine challenge (unchallenged and coccidial challenge). On day 14, birds were orally administered with coccidial vaccine or saline. On day 21, birds were killed to obtain jejunal tissue and mucosal samples for histological, gene expression and mucosal immunity measurements. Within 7 d of the challenge, there was a decrease in body-weight gain and feed intake, and an increase in the feed:gain ratio (P< 0·05). Jejunal inflammation was evidenced by villus damage, crypt dilation and goblet cell depletion. Coccidial challenge increased mucosal secretory IgA concentration and inflammatory gene (iNOS,IL-1β,IL-8andMyD88) mRNA expression levels (P< 0·05), as well as reduced jejunalMucin-2,IgAandIL-1RImRNA expression levels (P< 0·05). Increasing Arg concentration (1) increased jejunal villus height (P< 0·05) and linearly increased jejunal crypt depth (P< 0·05); (2) quadratically increased mucosal maltase activity (P< 0·05) and linearly decreased mucosal secretory IgG concentration (P< 0·05) within the coccidiosis-challenged groups; and (3) linearly decreased jejunal Toll-like receptor 4 (TLR4) mRNA expression level (P< 0·05) within the coccidiosis-challenged groups. The mRNA expression of mechanistic target of rapamycin (mTOR) complex 1 pathway genes (mTORandRPS6KB1) and the anti-apoptosis geneBcl-2quadratically responded to increasing dietary Arg supplementation (P< 0·05). These results indicate that dietary Arg supplementation attenuates intestinal mucosal disruption in coccidiosis-challenged chickens probably through suppressing TLR4 and activating mTOR complex 1 pathways.
Effect of phylloquinone (vitamin K1) supplementation for 12 months on the indices of vitamin K status and bone health in adult patients with Crohn's disease
Authors: O'Connor Eibhlís M. , Grealy Geraldine , McCarthy Jane , Desmond Alan , Craig Orla , Shanahan Fergus , Cashman Kevin D. 
Published: September 2014

Although epidemiological findings support a role for vitamin K status in the improvement of bone indices in adult patients with Crohn's disease (CD), this needs to be confirmed in double-blind, randomised controlled trials (RCT) with phylloquinone (vitamin K1). By conducting two RCT, the present study aimed to first establish whether supplementation with 1000 μg of phylloquinone daily near-maximally suppresses the percentage of undercarboxylated osteocalcin in serum (%ucOC; marker of vitamin K status) in adult patients with CD currently in remission as it does in healthy adults and second determine the effect of supplementation with phylloquinone at this dose for 12 months on the indices of bone turnover and bone mass. The initial dose-ranging RCT was conducted in adult patients with CD (n 10 per group) using 0 (placebo), 1000 or 2000 μg of phylloquinone daily for 2 weeks. In the main RCT, the effect of placebo v. 1000 μg vitamin K/d (both co-administered with Ca (500 mg/d) and vitamin D3 (10 μg/d)) for 12 months (n 43 per group) on the biochemical indices of bone turnover (determined by enzyme immunoassay) and bone mass (determined by dual-energy X-ray absorptiometry) were investigated. At baseline, the mean %ucOC was 47 %, and this was suppressed upon supplementation with 1000 μg of phylloquinone daily ( − 81 %; P< 0·01) and not suppressed further by 2000 μg of phylloquinone daily. Compared with the placebo, supplementation with 1000 μg of phylloquinone daily for 12 months had no significant effect (P>0·1) on bone turnover markers or on the bone mass of the lumbar spine or femur, but modestly increased (P< 0·05) the bone mass of the total radius. Despite near maximal suppression of serum %ucOC, supplementation with 1000 μg of phylloquinone daily (with Ca and vitamin D3) had no effect on the indices of bone health in adult CD patients with likely vitamin K insufficiency.
Effectiveness and persistence of arbuscular mycorrhizal fungi on the physiology, nutrient uptake and yield of Crimson seedless grapevine
Authors: NICOLÁS E. , MAESTRE-VALERO J. F. , ALARCÓN J. J. , PEDRERO F. , VICENTE-SÁNCHEZ J. , BERNABÉ A. , GÓMEZ-MONTIEL J. , HERNÁNDEZ J. A. , FERNÁNDEZ F. 
Published: September 2014

SUMMARYIn the present study, carried out in South-eastern Spain, a commercial arbuscular mycorrhizal fungus (AMF;Glomus iranicumvar.tenuihypharumsp.nova) was introduced through drip irrigation to inoculate Crimson grapevines. Their effects on the physiological and nutritional activity were evaluated for 2 years (2011–12). Additionally, during the second year of experimentation, the persistence of mycorrhizae on the grapevine and their effects were innovatively analysed.The AMF satisfactorily colonized the Crimson grapevine roots, improved the plants water status, induced an improvement in the photosynthetic performance that increased the water use efficiency, promoted the uptake of phosphorus (P), potassium (K) and calcium (Ca) and led to a mobilization of starch reserves in the apex in winter, which was possibly responsible for enhancing root development. Moreover, inoculated plants had significantly increased yield and improved quality of grapes, which led to early grape maturation. Overall, the persistent effect of AMF during the second year produced similar positive effects, although to a lesser extent, to those obtained in the inoculated treatment.The results found in the present study show that this AMF application technique can be recommended for sustainable agriculture in arid and semi-arid areas. Moreover, as a result of the competition with the native mycorrhizae, periodic monitoring of the percentage of mycorrhizal colonization and re-inoculation in order to obtain all the positive effects evidenced in the inoculated treatment is recommended.
Morbidity and mortality associated with subglottic laryngotracheal stenosis in granulomatosis with polyangiitis (Wegener's granulomatosis): a single-centre experience in the United Kingdom
Authors: Jordan N P , Verma H , Siddiqui A , Morrison G A , D'Cruz D P 
Published: September 2014

AbstractObjectives:We aimed to determine the prevalence of symptomatic subglottic laryngotracheal stenosis in patients with granulomatosis with polyangiitis (Wegener's granulomatosis); we also wanted to characterise the clinical outcomes and surgical interventions required, and the relapse rate in our cohort.Methods:We undertook a retrospective clinical review of all granulomatosis with polyangiitis patients with symptomatic subglottic laryngotracheal stenosis attending St Thomas' Hospital, London, United Kingdom.Results:Symptomatic subglottic laryngotracheal stenosis developed in 16 per cent of granulomatosis with polyangiitis patients attending our clinic. The median age of patients at diagnosis was 44 years (range: 34–81 years); 78 per cent of those presenting with subglottic laryngotracheal stenosis were women and 22 per cent were men. All patients were white; 67 per cent of patients were proteinase 3-antineutrophil cytoplasmic antibody-positive and 67 per cent developed relapsing disease requiring repeated surgical intervention. Subglottic laryngotracheal stenosis relapse was not associated with active systemic vasculitis elsewhere.Conclusion:Subglottic laryngotracheal stenosis is an uncommon but significant complication of granulomatosis with polyangiitis. Management of subglottic laryngotracheal stenosis requires a multi-disciplinary approach, with both rheumatological and otolaryngological expertise involved, given the relapsing nature of the disease.
How images make world politics: International icons and the case of Abu Ghraib
Authors: HANSEN LENE 
Published: September 2014

AbstractThis article introduces international icons to the field of International Relations. International icons are freestanding images that are widely circulated, recognised, and emotionally responded to. International icons come in the form of foreign policy icons familiar to a specific domestic audience, regional icons, and global icons. Icons do not speak foreign policy in and of themselves rather their meaning is constituted in discourse. Images rise to the status of international icons in part through images that appropriate the icon itself, either in full or through inserting parts of the icon into new images. Appropriations might be used and read as critical interventions into foreign policy debates, but such readings should themselves be subjected to analysis. A three-tier analytical and methodological framework for studying international icons is presented and applied in a case study of the hooded prisoner widely claimed to be emblematic of the Abu Ghraib prison scandal.
Adaptive vector sliding mode fault-tolerant control of the uncertain Stewart platform based on position measurements only
Authors: Meng Qiang , Zhang Tao , He Jing-feng , Song Jing-yan 
Published: September 2014

SUMMARYThis paper investigates the trajectory tracking of a Stewart platform, which is a typical multi-input multi-output nonlinear system, with unmodeled dynamics, parameter uncertainties, friction, and unpredictable actuator faults. An adaptive vector sliding mode fault-tolerant control law is derived to ensure the system is insensitive to uncertainties and drive the state variable errors of the closed-loop system to converge to the origin. Moreover, novel adaptive laws are proposed to update the upper boundary of uncertainty according to the actual system state, which greatly reduces the chattering of sliding mode control. Furthermore, velocity signals are estimated by introducing a simple nonlinear observer, resulting in the proposed controller requiring position measurements only. Finally, numerical simulations illustrate the effectiveness of the proposed control scheme.
ICT AND THE FUTURE OF HEALTH CARE: ASPECTS OF DOCTOR-PATIENT COMMUNICATION
Authors: Haluza Daniela , Jungwirth David 
Published: September 2014

Objectives: The current digital revolution is particularly relevant for interactions of healthcare providers with patients and the community as a whole. The growing public acceptance and distribution of new communication tools such as smart mobile phones provide the prerequisite for information and communication technology (ICT) -assisted healthcare applications. The present study aimed at identifying specifications and perceptions of different interest groups regarding future demands of ICT-supported doctor–patient communication in Austria.Methods: German-speaking Austrian healthcare experts (n = 73; 74 percent males; mean age, 43.9 years; SD 9.4) representing medical professionals, patient advocates, and administrative personnel participated in a 2-round online Delphi process. Participants evaluated scenario-based benefits and obstacles for possible prospect introduction as well as degree of innovation, desirability, and estimated implementation dates of two medical care-related future set ups.Results: Panelists expected the future ICT-supported doctor–patient dialogue to especially improve the three factors doctors–patient relationship, patients’ knowledge, and quality of social health care. However, lack of acceptance by doctors, data security, and monetary aspects were considered as the three most relevant barriers for ICT implementation. Furthermore, inter-group comparison regarding desirability of future scenarios showed that medical professionals tended to be more skeptical about health-related technological innovations (p < .001).Conclusions: The findings of this survey revealed different expectations among interest groups. Thus, we suggest building taskforces and using workshops for establishing a dialogue between stakeholders to positively shape the future of ICT-supported collaboration and communication between doctors and patients.
Hemolymph microbiome of Pacific oysters in response to temperature, temperature stress and infection
Authors: Lokmer Ana , Wegner Karl Mathias 
Published: September 2014

Abstract
Microbiota provide their hosts with a range of beneficial services, including defense from external pathogens. However, host-associated microbial communities themselves can act as a source of opportunistic pathogens depending on the environment. Marine poikilotherms and their microbiota are strongly influenced by temperature, but experimental studies exploring how temperature affects the interactions between both parties are rare. To assess the effects of temperature, temperature stress and infection on diversity, composition and dynamics of the hemolymph microbiota of Pacific oysters (Crassostrea gigas), we conducted an experiment in a fully-crossed, three-factorial design, in which the temperature acclimated oysters (8 or 22 °C) were exposed to temperature stress and to experimental challenge with a virulent Vibrio sp. strain. We monitored oyster survival and repeatedly collected hemolymph of dead and alive animals to determine the microbiome composition by 16s rRNA gene amplicon pyrosequencing. We found that the microbial dynamics and composition of communities in healthy animals (including infection survivors) were significantly affected by temperature and temperature stress, but not by infection. The response was mediated by changes in the incidence and abundance of operational taxonomic units (OTUs) and accompanied by little change at higher taxonomic levels, indicating dynamic stability of the hemolymph microbiome. Dead and moribund oysters, on the contrary, displayed signs of community structure disruption, characterized by very low diversity and proliferation of few OTUs. We can therefore link short-term responses of host-associated microbial communities to abiotic and biotic factors and assess the potential feedback between microbiota dynamics and host survival during disease.
The contribution of frequency-specific activity to hierarchical information processing in the human auditory cortex
Authors: Fontolan L. , Morillon B. , Liegeois-Chauvel C. , Giraud Anne-Lise 
Published: September 2014

AbstractThe fact that feed-forward and top-down propagation of sensory information use distinct frequency bands is an appealing assumption for which evidence remains scarce. Here we obtain human depth recordings from two auditory cortical regions in both hemispheres, while subjects listen to sentences, and show that information travels in each direction using separate frequency channels. Bottom-up and top-down propagation dominates in γ- and δ–β (<40 Hz) bands, respectively. The predominance of low frequencies for top-down information transfer is confirmed by cross-regional frequency coupling, which indicates that the power of γ-activity in A1 is modulated by the phase of δ–β activity sampled from association auditory cortex (AAC). This cross-regional coupling effect is absent in the opposite direction. Finally, we show that information transfer does not proceed continuously but by time windows where bottom-up or top-down processing alternatively dominates. These findings suggest that the brain uses both frequency- and time-division multiplexing to optimize directional information transfer.
Significant change of spin transport property in Cu/Nb bilayer due to superconducting transition
Authors: Ohnishi Kohei , Ono Yuma , Nomura Tatsuya , Kimura Takashi 
Published: September 2014

AbstractThe combination between the spin-dependent and super-conducting (SC) transports is expected to provide intriguing properties such as crossed Andreev reflection and spin-triplet superconductivity. This may be able to open a new avenue in the field of spintronics, namely superconducting spintronics because a superconductor itself has great potential for future nanoelectronic applications. To observe such SC spin transports, the suppression of the extrinsic effects originating from the heating and Oersted field due to the electric current is a crucial role. Pure spin current without accompanying the charge current is known as a powerful mean for preventing such extrinsic effects. However, non-negligible heat flow is found to exist even in a conventional pure spin current device based on laterally-configured spin valve because of the heating around the spin injector. Here, we develop a nanopillar-based lateral spin valve, which significantly reduces the heat generation, on a superconducting Nb film. By using this ideal platform, we found that the spin absorption is strongly suppressed by the SC transition of Nb. This demonstration is the clear evidence that the super-conducting Nb is an insulator for the pure spin current.
Exciton density pattern formation in laser irradiated quantum wells under electrodes of various shapes
Authors: Tomylko V. V. , Goliney I. Yu. , Chernyuk A. A. , Sugakov V. I. 
Published: September 2014

(Submitted December 18, 2013)
The condensation of indirect excitons in double quantum wells is studied in an electric field created by electrodes of different shapes. The finite value of the exciton lifetime, the pumping and nonuniformity of the electric field under the electrode are taken into account. It is shown that islands of exciton condensed phase emerge under electrodes when the pumping exceeds a certain threshold value. They appear first under the rim where the potential energy of excitons has a dip. Calculations predict a complicated evolution of the exciton density distribution: from the gaseous phase at low laser intensities to the condensed phase in the whole area under the electrode at larger intensities. Therefore, the configurations of the exciton condensed phase may be manipulated by choosing the setups with conductive electrodes of different shapes via forming specific potentials of the electrical field and controlled by the level of the laser irradiation.
The shape, internal structure and gravity of the fast spinner β Pictoris b
Authors: Kong Dali , Liao Xinhao , Zhang Keke , Schubert Gerald 
Published: September 2014

Abstract
A young extrasolar gas giant planet, β Pictoris b, recently discovered in the β Pictoris system, spins substantially faster than the giant gas planets Jupiter and Saturn. Based on the newly measured parameters – the rotation period of the planet, its mass and radius – together with an assumption that the gas planet β Pictoris b is in hydrostatic equilibrium and made of a fully compressible barotropic gas with a polytropic index of unity, we are able to compute, via a hybrid inverse method, its non-spherical shape, internal density/pressure distribution and gravitational zonal coefficients up to degree 8. Since the mass Mβ for the planet β Pictoris b is highly uncertain, various models with different values of Mβ are studied in this Letter, providing the upper and lower bounds for its shape parameter as well as its gravitational zonal coefficients. If Mβ is assumed to be 6MJ with MJ being Jupiter's mass, we show that the shape of the planet β Pictoris b is approximately described by an oblate spheroid whose eccentricity at the one-bar surface is $\mathcal {E}_{\beta }=0.369\,28$ with the gravitational coefficient (J2)β = +15 375.972 × 10−6. It follows that our results open the possibility of constraining or inferring the mass Mβ of the planet β Pictoris b if its shape can be measured or constrained. By assuming that the planet β Pictoris b will shrink to the size of Jupiter in the process of cooling down and, hence, rotate much faster, we also calculate the future shape and internal structure of the planet β Pictoris b.
Diurnal activity patterns and feeding ecology of the endemic geladas (Theropithecus gelada) in the Simien Mountains National Park, Ethiopia
Authors: Ejigu Dessalegn , Bekele Afework 
Published: September 2014

AbstractDiurnal activity patterns and feeding ecology of geladas (Theropithecus gelada) in Chenek, Simien Mountains National Park, were studied from January 2010 to April 2010. Data were gathered for 7 days per month starting from early in the morning to dusk. The study site (1805 ha) was divided into five blocks and a total of 397 individuals were counted using simultaneous census method. One band with 21 individuals was selected as a study group and scan sampling was used to study their diurnal activity patterns and feeding ecology. Geladas dedicated significantly more time to foraging than to other diurnal activities. They spent the majority of feeding time foraging on grass, and allocated little time to feeding on leaves, shoots, and flowers. Geladas of all age classes devoted the least time to resting, and spent similar amount of time moving. The study band was observed to interact with people, and to steal food from tourists and local people. Raising local people's awareness of geladas ecology and behavior might be a necessary component in the species' successful management and conservation.
Megalopapilla in children: a spectral domain optical coherence tomography analysis
Authors: Lee Hyo Seok , Park Sang Woo , Heo Hwan 
Published: September 2014

AbstractPurposeTo compare various optic nerve head (ONH) parameters and peripapillary retinal nerve fibre layer (pRNFL) thickness between megalopapilla cases and normal control using spectral domain optical coherence tomography (SD‐OCT) in children.MethodsFifty eyes with megalopapilla and 80 normal control eyes of totally 130 children between the ages of 6 and 15 were examined using SD‐OCT. Optic nerve head parameters including disc diameter, cup‐to‐disc ratio, disc area, cup area, rim area, cup volume and rim volume, and pRNFL thickness were analysed and compared between two groups.ResultsMegalopapilla group presented larger optic disc diameter, disc and cup area, cup‐to‐disc and cup‐to‐disc area ratio, when compared with normal control group. However, there is no difference in rim area (p = 0.25) and rim volume (p = 0.48) between the two groups. Average pRNFL thickness was higher in the megalopapilla group (p < 0.001).ConclusionsRim area, rim volume and pRNFL, which reflect the number of retinal nerve fibres, were preserved in children with megalopapilla. Various ONH parameters obtained with SD‐OCT may be useful in the differential diagnosis of megalopapilla in children.
Beyond (But Including) the CEO: Diffusing Corporate Social Responsibility throughout the Organization through Social Networks
Authors: Jacobson Kathryn J. L. , Hood Jacqueline N. , Van Buren Harry J. 
Published: September 2014

AbstractChief Executive Officers and other organizational leaders can affect how corporate social responsibility initiatives are perceived in their organizations. However, in order to be successful with regard to promoting CSR, leaders need to have strong network competencies and to move beyond charismatic leadership. In this paper we offer a critique of charismatic leadership as it relates to CSR, posit that the intellectual stimulation brought about by transformational leadership is more important in this regard, propose that internal and networking is a leadership competence highly relevant to CSR, and emphasize the importance of working through highly credible opinion leaders in promoting CSR.