bluuebunny/crossref_metadata_2025_split huggingface dataset:
1120 – Self-image In a Sample Of Italian Women With Eating Disorders
Authors: Focà F. , Luci G. , Guarino G. , Moroni V. , Fanella F. 
Published: July 2013

IntroductionStructural Analysis of Social Behaviour by L.S. Benjamin as revised by Scilligo represents self image by two axes: affiliation with love and hate as extreme points; interdependence with freedom and control as extreme points. Axes define a circumplex with 4 quadrants: loving freedom; hostile freedom; hostile control, loving control. Psychic wellness consists of high loving control and freedom and low hostile control and freedom. Quadrants are divided into 12 clusters: self-emancipation, self-affirmation, self-exploration, self-acceptance, self-protection, self-regulation, self-limitation, self-blame, self-attack, self-rejection, self-neglect, self-isolation.ObjectiveThe present study aims to enrich knowledge about intrapsychic world of people with Eating Disorders by analyzing self image of diagnostic subtypes.AimsDifferentiating diagnostic subtypes self image in order to have a new key to choose therapeutic interventions.Methods250 women with ED, outpatients of the ED Unit of an Italian General Hospital, were administered the Intrex questionnaire, the operational definition of the 12 clusters. One-way ANOVA and post-hoc comparisons between diagnostic subtypes were performed.ResultsResults indicate that ED patients have negative self-image. Bulimics show the highest level of self-blame, self-attack and self-rejection and the lowest of self-affirmation, self-exploration, self-acceptance, self-protection; anorexics show the highest level of self-regulation and self-limitation together with poor self-affirmation, self-exploration, self-acceptance. BED and EDNOS profiles appear less self attacking and more self acceptant.ConclusionsEating disorder diagnostic subtypes seem to have distinct intrapsychic profiles that can be reflected in different interpersonal behaviours. Such knowledge may help the therapist to choose the better interpersonal position to support therapeutic change.
1127 – Evolution Of Addictive Comorbidities In a Group Of Patients Diagnosed With Schizophrenia During Atypical Antipsychotic Treatment
Authors: Vasile D. , Macovei R.A. , Vasiliu O. , Mangalagiu A.G. , Tudor C. 
Published: July 2013

BackgroundDrug-related disorders are observed in 30–50% of the patients diagnosed with schizophrenia and is therefore an important problem to be adressed in clinical practice. There are many reasons for the overlap between addictive disorders and schizophrenia: the tendency to alleviate antipsychotic-related side effects, the need to decrease anxiety or depression, to interfere with sensory gating defficits etc.ObjectiveTo assess the effects of atypical antypsychotic treatment in decreasing the drug of abuse consumption in a population of schizophrenia diagnosed patients.MethodsA group of 23 patients, diagnosed with schizophrenia and a drug related disorder (dependence 52.1%, polisubstance dependence 17.4%, substance abuse 26%, other 4.5%), according to DSM IV TR criteria, were monitored for 6 months, while being treated with atypical antipsychotics (olanzapine 43.4%, risperidone 34.7%, aripiprazole 17.4%, amisulpride 4.5%), using Positive and Negative Syndrome Scale for Schizophrenia (PANSS), Clinical Global Impressions (CGI) and Inventory of Drug Taking Situations (IDTS) every 4 weeks.ResultsThe evolution of IDTS scores were not parallel to the PANSS evaluations: while the psychotic symptoms decreased continuously during the 6 months of the study (-40.5% at week 12 and -67.5% at endpoint), the IDTS decreased initially (- 33.2% at week 12) but increased slightly to the end of the study (-31.2% at endpoint). The CGI-I score has a decrease of 50.4% at week 12 and of 55.6% at week 24.ConclusionsThe evolution of drug related disorders during the atypical treatment of schizophrenia doesn’t correlate with the severity of psychosis and necessitates a specific management.
1134 – Integrated Assessment The Effectiveness Of Therapy By Cipralex In Patients With Rheumatoid Arthritis With Anxiety And Depressive Disorders
Authors: Spikina A. , Sofronova M. , Sofronov A. 
Published: July 2013

Rheumatoid arthritis (RA) is one of psychosomatic diseases, the clinical picture which is the important place occupied by psychiatric disorders. Anxiety and depressive symptoms may have a primary character and provoke the development of the disease or is secondary occur against the background of a long course of the disease and its exacerbations.Purpose of the studyDifferentially study the effect of antidepressant Cipralex on higher cortical function and on affective patients with rheumatoid arthritis.Characteristic of the material: For the study groups were formed with the diagnosis rheumatoid arthritis, remission. All patients received standard therapy non-steroidal anti-inflammatory drugs and antidepressant Cipralex.DiscussionShould first be noted that the study confirmed the clinical efficacy of the Cipralex in therapy of anxiety and depressive disorders in RA. Therapeutic results were achieved in most cases. (98%)In summary, these data show the effectiveness of the complex treatment of RA. The quality of life in patients with RA affects of factors, including not only the patient's medical condition, but also affective and cognitive areas. The study found the optimizing effect of the drug on cognition. This is evidenced by the fact that on the background of therapy by Cipralex was reduction in the total amount of time required to perform the test tasks and reducing the number of mistakes.Results obtained in the study of data leads to the conclusion that Cipralex may be included in the complex therapy of patients with RA.
1135 – Mental Health Distress And Alcohol Misuse Associated With Prevalence Of Sexually Transmitted Infections Among Adolescents In Care
Authors: Haley N. , Lambert G. , Jean S. , Frappier J.-Y. , Otis J. , Roy E. 
Published: July 2013

IntroductionEvery year 4,000 to 5,000 adolescents reside in Quebec Youth Protection Centers (YPCs). Many youth have risky behaviours and mental health issues that put them at risk for sexually transmitted infections (STIs).ObjectivesDocument the prevalence of STIs (chlamydia and gonorrhoeae) among adolescents aged 14-17 years old entering Quebec residential YPCs and identify associated risk factors.MethodsIn 2008–2009, adolescents residing in six YPCs completed a questionnaire covering sexual and substance use behaviours, as well as other health issues affecting their well-being. Urine samples were collected for Chlamydia trachomatis (CTGI) and Neisseria gonorrhoea (NGGI) genital infections.ResultsAmong 578 participants, 14-17 years old, 89% were sexually active. Risk behaviours included: early sexual initiation (66% < 14 years); multiple partners (median: girls 5, boys 8); group sex (girls 38%, boys 43%); sex for money or goods (girls 27%, boys 8%). Half of sexual relations were under the influence of drugs/alcohol. Regular substance use (3x weekly and +) was: tobacco: 75.0%; cannabis: 63.1%; alcohol: 24.2%; amphetamines: 16.7%; and cocaine: 7.4%. Prevalence of CTGI: 9.3% girls, 1.9% boys; NGGI: 1.7% girls, 0% boys. In multivariate analysis, factors significantly associated with chlamydia infection among girls were: alcohol intoxication hospitalisation or history of suicide ideation with plan.ConclusionSerious alcohol misuse or mental distress were significantly associated with STI infections among adolescents. Mental health professionals are encouraged to provide sexual health and substance use counselling with adolescent patients given the highly woven interaction between mental distress and risk of sexually transmitted infections.
1136 – Bridging The Gap: An Audit Of The Transitions Of Young People In Mental Health Services
Authors: George D. , Prasad K. , Denton R. , Routledge D. , Sweet D. 
Published: July 2013

IntroductionTransitions from Child and Adolescent Mental Health Services (CAMHS) to Adult Mental Health Services (AMHS) can often be problematic due to high eligibility thresholds, inconsistent support during transition and limited participation from young people. The TRACK Study highlighted several clinical, organizational and policy related reasons for Services to develop and implement transition protocols effectively.Aims and objectivesThis audit aims to examine whether the Trust's Transitions Policy is adhered to during transitions of young people across services. It also aims to review the qualitative experience of young people and professionals involved.MethodA Questionnaire Survey method was used to collect quantitative and qualitative data from involved professionals and young people who moved from CAMHS into AMHS (Aug11–Jan12). The data was analyzed against the audit criteria, which relate to specific aspects of the Transitions Policy.ResultsA variable response rate showed that majority of the young people and involved professionals were satisfied with the planning and transfer of care with high policy adherence rates. Young people wished for better communication, more information on the nature of services offered and greater support, while professionals hoped for greater consideration of engagement levels and joint working. Alternative support was requested for declined referrals.ConclusionsImproved adherence to the Transitions Policy can be achieved through proper planning, better communication, more joint working and regular feedback from young people and professionals. It can also help to achieve higher standards and continuity of clinical care to meet the needs of young people.
1144 – Crimes And Mental Elderly Patients In Psychiatric Hospital Of Razi In Tunisia
Authors: Mâamri A. , Chennoufi L. , Hadj Salem M. , Melki W. , Ridha R. 
Published: July 2013

IntroductionFew scientific studies have been devoted to the study of crime among the mentally ill elderly, however, all the studies agree on the importance of recognizing risk factors associated with passage to forensic action in elderly patients.AimsThe objectives of our work are to clarify the sociodemographic, clinical and forensic characteristic of mental elderly patients who commit forensic acts.MethodologieOur work has focused on all patients older than 60 years hospitalized under the mode of office between 1995 and 2012 in the service of forensic Razi hospital according to article 29 of the law n° 92–83 of the third of August 1992 as amended by the law 2004-40 of 3 May 2004, following a non-legal place due to insanity within the meaning of the 38 article of the Tunisian Penal Code.ResultsOur study included 25 patients, their ages ranged between 60 and 90 years. They mostly had a low socio-economic level (64%), a low educational level (48%) and a marital status of married (64%).All patients had a neuropsychiatric disease: schizophrenia and other psychotic disorders in 48% of cases, dementia and Delirium nonspecific in 32% of cases, mood disorder in 16% of cases and mental retardation in 4% of cases. The medico-legal act was murder or attempted murder in 40% of cases, sexual crimes in 16% of cases, aggression against property in 16%, violence against people in 8% of cases and different offenses in the remaining cases.
1152 – Formalized Consensus Guidelines For Use And Management Of Antipsychotic Depots
Authors: Samalin L. , Guillaume S. , Abbar M. , Courtet P. , Lancrenon S. , Llorca P.-M. 
Published: July 2013

IntroductionAs part of a process to improve the quality of care, the Association for Biological Psychiatry and Neuropsychopharmacology (AFPBN) developed recommendations for the use and management of Long Acting Injectable (LAI) Antipsychotics in clinical practice.MethodsBased on a literature review, a written survey was prepared that asked about 539 options in 32 specific clinical situations. We contacted 64 national experts, 42 (65,6%) completed the survey. According to the answers for each situation based on a 9-points scale, a categorical rank (first-line/preferred choice, second-line/alternate choice, third-line/usually inappropriate) was assigned to each option. First-line option was defined as a strategy rated as 7–9 (extremely appropriate) by at least 50% of the experts.ResultsFor French experts, LAI Antipsychotics are indicated in patients with schizophrenia, schizoaffective disorder and bipolar disorder. According to their efficacy and tolerability risperidone LAI then olanzapine LAI are recommended as first line for maintenance treatment in schizophrenia, even after the first episode. Depot neuroleptics are recommended as second line for maintenance treatment in schizophrenia. LAI Second Generation Antipsychotics are recommended as second line in bipolar disorder. Several clusters of patients are identified, characterizing a specific profile for the use of LAI. Recommendations for the use of LAI and switch from oral to injectable formulations are suggested.ConclusionThe use of LAI has advantages as maintenance treatment but their prescription rate is generally below 30% in different countries. Specific guidelines for the use and management of this formulation could improve their use in clinical practice.
1162 – Vascular Factor In The Etiology And Pathogenesis Of Alzheimer’s Disease
Authors: Maksimovich I.V. 
Published: July 2013

IntroductionVascular factor is very important in the development of AD. The research investigates the changes in the cerebral angioarchitectonics at various AD stages.MethodsThe research included 92 patients of which:Test Group: 47 aged 34–79 suffering from AD different stages including:4 with preclinical stages or high risk of disease development (TDR-0);15 with mild dementia (TDR-1);20 with moderate dementia (TDR-2);8 with severe dementia (TDR-3).Control Group: 45 aged 28–78 with various types of brain lesions accompanied by dementia but without Alzheimer’s disease including:15 with chronic cerebrovascular insufficiency of atherosclerotic genesis and moderate dementia;12 with severe vascular dementia;14 with atherosclerotic parkinsonism;4 with Parkinson’s disease.Each patient underwent MRI, CT, SG, REG, MUGA.ResultsAt AD different stages, changes in angioarchitectonics and microcirculation show themselves in:lack of expressed atherosclerotic lesions of intracranial vessels - 47 (100%) patients,reduction of capillary bed in the temporal and frontoparietal regions - 47 (100%),development of multiple arteriovenous shunts in the same areas - 47 (100%),corresponding early venous shunts - 47 (100%),abnormal development of venous trunks receiving blood from arteriovenous shunts - 42 (89.4%),venous congestion at frontal and parietal region border - 43 (91.5%),increased loop fromation of intracranial arteries - 37 (78.7%).Control group patients had no combination of such changes.ConclusionsWe named the vascular factor in AD “the discirculatory angiopathy of Alzheimer’s type” (DAAT).
1173 – The Results Of a Smoking Cessation Center - a Preliminary Study
Authors: Hacihanifioglu S.B. , Yazici E. 
Published: July 2013

AimSmoking is still one of the important public health problems. Utilizing professional support for cessation increases the rates of success. A retrospective analysis of one year data of a smoking cessation center (SCC) is presented in this study.MethodsData obtained from 92 patients by using sociodemografic questionnaire and Fagerstrom test for nicotine dependence (FTND). Quitting or remaining in the program and success rates of cessation were determined.ResultsFemale/male ratio was 52.2% /47. 8% (mean age 40.67 ± 11.18). The mean FTND score was 5.23 ± 1.76. 66.3% of participants had no previous psychiatric treatment. 18.5 % of participants had history of psychiatric treatment and 15.2% had ongoing treatment. Smokers received pharmacotherapy and CBT; CBT alone or pharmacotherapy alone. After first examination, 33% of all participants continued to their treatment program. There was no difference between the attendants or quitters of the program for sociodemografics, treatment history or FTND scores. Seven attendants in the program (32 % of the attendants) quitted smoking; nine attendants (41%) decreased daily number of smoking more than 50%. Six attendants (27%) had no change. There was no difference between the quitters or no quitters for sociodemografics, psychiatric treatment history or FTND scores.ConclusionsWe presented a preliminary analysis of our SCC program data. It is reported that psychiatric disorders are related with higher rates of smoking and lower rates of cessation. In this study the anamnesis of psychiatric disorders had no negative influence on cessation of smoking.
1178 – Correlation Study Of Apoptosis-related Genes Bcl-2, Bax And Ptsd In Rat Medial Prefrontal Cortex Neuronal Apoptosis
Authors: Li Y. , Han F. , Shi Y. 
Published: July 2013

Post-traumatic stress disorder (PTSD) is a significant problem,The medial prefrontal cortex (mPFC) is known to be significantly involved in emotional adjustment.ObjectiveTo discuss the issue of post-traumatic stress disorder (PTSD) rat apoptosis-related genes Bcl-2, Bax and medial prefrontal cortex (mPFC) neuronal apoptosis, and to provide experimental evidence to reveal PTSD pathogenesis.MethodsThe single-prolonged stress(SPS) method was used to set up the rat PTSD models There were five groups after SPS 1 day 4 days 7 days 14 days groups and control group Serum corticosterone level was determined with chemiluminescence, mPFC neuronal apoptosis changes and detection of apoptotic index were detected with transmission electron microscopy, hoechst 33342 staining and in situ nick end labeling method (TUNEL) staining. Immunohistochemistry, immunofluorescence, RT-PCR and western blotting were used to detect the expressions of Bcl-2 and Bax in the medial prefrontal cortex neuronal.ResultsPTSD rat mPFC neuron cell apoptosis, the number of apoptotic cells gradually increased with time and reached a peak at 7 days after SPS stimulates. Bcl-2 expression reached a peak at 4d and Bax expression reached a peak at 7d after SPS stimulates, Bcl-2/Bax ratio transient increased and then gradually decreased, reached a lowest point in seventh days after SPS stimulates.ConclusionsThe expression of apoptosis related genes Bcl-2 and Bax increase and their ratio imbalances are likely to be one of the reasons that lead to PTSD in rat mPFC neurons apoptosis, which may provide the pathophysiology basis for PTSD.
1182 – Rcts Schizophrenia Quality In Russian Speaking Patients: a Systematic Review Of Quetiapine Comparison Trials
Authors: Orlova N. , Shkliar M. 
Published: July 2013

ObjectiveThe systematic review help determinated of RCT’s quality at Russian speaking patients.Materials and methodsWere search the Russian Scientific Journals in Consilium medicum Database for RCTs comparing quetiapine with any other pharmacotherapy or placebo in the treatment of patients with schizophrenia. Effect sizes were combined in a fixed-effects model. To quantify heterogeneity was used the Q test. Funnel plots, regression tests were used to evaluate publication bias. Analyses were performed using RevMan 5. Methodological quality of controlled trials was assessed by Jadad score.ResultsFrom 25 relevant trials only 5 trials were finally included in the review; None of that trials were identified in main Western data bases. All studies were randomized; None of the authors reported about study blinding; Only 2 studies reported about withdrawals and dropouts; None of the studies reported voluntary participation. Median Jadad score - 3 (57%). Quality of the study in most trials was low, and sample sizes were small. Mean quetiapine dose was slightly lower than in Western studies. Quetiapine at Russian speaking patients with schizophrenia was more effective and better tolerated than haloperidol but had no differences in those parameters between risperidon and olanzepine.SummaryWas found: low quality of RCTs in Russian speaking patients; comparative antipsychotics had similar profiles of tolerability and safety for positive, negative symptoms and patient’s compliance. Coming RCTs must be thoroughly planned for studying in initial criterion safety and tolerability of all antipsychotics for schizophrenia treatment. We need further long-term studies for side effects monitoring.
1186 – Phobic Postural Vertigo - a Blurred Sign For Anxiety Disorder, Results Form a Case Series
Authors: Feffer K. , Gordon C. , Fennig S. 
Published: July 2013

Phobic Postural Vertigo (PPV) is the 3rd most common cause for vertigo, characterized by the combination of a dizziness and subjective disturbance of balance in the absence of objective findings during routine Neurological evaluation. In most cases the clinical presentation is indistinguishable from agoraphobia. Despite this, most clinical data does not support direct correlation between anxiety disorder and PPV.In this case series 10 patients who suffer from PPV went through psychiatry interview after a neurologist check up has been made to confirm the diagnosis of PPV. ACQ, BCQ and HDRS were filled for all patients.ResultAccording to this preliminary case series evidence for anxiety/somatization disorder were evident in 50% (5/10) before the development of PPV while in 30% (3/10) anxiety symptoms appeared in parallel or sequential to the development of PPV. In 20% (2/10), no signs for anxiety symptoms detected during evaluation.The results of this case series suggest that PPV is a heterogeneous diagnosis that in part includes patient with previous anxiety/somatization disorder and patient in which vertigo is the presenting sign of anxiety disorder.Farther research is needed in order to farther characterize PPV patients and promote suitable interventions.
1189 – Kleine-levin Syndrome And Lithium
Authors: Yelmo S. , Morera-Fumero A.L. , Díaz-Marrero G. , Suárez-Benítez N. , González-González I. , Quandt-Herrera P. 
Published: July 2013

IntroductionKleine-Levin syndrome (KLS) is a rare disease characterized by recurrent episodes of hypersomnia, hyperphagia and behavioural symptoms, mainly hypersexuality.ObjectivesWe report the clinical course of KLS in a 18-year-old male. The clinical onset and evolution are described.Aims/methodsThe boy was diagnosed as having KLS after two episodes of hypersomnia lasting for 13 to 15 days each one. When awake, he was depressed and with megaphagia. He also had phases of hypersexuality. The initial interval between episodes was 6 weeks. After the second episode was treated with lithium and remained free of symptoms for 11 months. He had a third episode that lasted 6 days. Serum lithium level was low. In this third episode he had only hypersomnia. He had a relapse two years later with a duration of 4 days, without further relapses.ResultsKLS is more frequent in young males with a mean duration of 8 years and around 7 episodes that lasted 10 days. The pathogenesis remains unknown. It has been related with functional disturbance in the hypothalamus, viral infections, triggering stimulus...Some authors consider KLS as a variant of bipolar disorder. Treatment includes methylphenidate, neuroleptics, antidepressants and mood stabilizers as lithium. With lithium has been reported fewer relapses, shorter duration of episodes and disappearance of behavioural symptoms.ConclusionsDespite being a rare disease, is thought to be underdiagnosed, because diagnosis is mainly clinical, and tests such as EEG, PSG and MSLT reinforce the diagnosis but are not pathognomonic. Today, lithium is the best treatment option.