bluuebunny/crossref_metadata_2025_split huggingface dataset:
Visualization and purchase
Authors: Marchini Andrea , Diotallevi Francesco , Paffarini Chiara , Stasi Antonio , Baselice Antonio 
Published: June 2015

Purpose
– The purpose of this study is to present an attempt to evaluate Italian olive oil brand competition thought the analysis of consumers’ visual perspective.

Design/methodology/approach
– Through the implementation of a new information technology system called “Visual Marketing REL”, which furnishes eye-tracking measures, the authors were able to produce important information relative to the layout organization of to the Italian olive oil shelf, a strategic product of the agro-food chain. The research uses the “in situ” testing of the software developed.

Findings
– The research, following up the thesis of sensorial marketing affecting choices, intends to identify an IT tool to facilitate the design of the shelf by increasing the efficiency of the retail mix. Results highlight that specific positioning could impact the differentiation effect and orientate consumers’ choices, thus increasing the efficiency of the retail mix.

Research limitations/implications
– To generalize the results would require many repetitions of different product categories. In this case, it would be possible to quantify the levels of correlation between visual information and sales.

Practical implications
– This work opens important considerations in terms of strategic management of modern distribution, leaders and minor brands competitive relationship, as well as opportunities for producers of high-quality products, which could address their strategies to differentiation and niche market in cooperation with retailers.

Social implications
– The research aims to encourage the process of consumer choice and reduce information asymmetries.

Originality/value
– The most important result is the connection among choices, visualization, differentiation strategy and positioning/ordering on the shelf. The layout management, in fact, could be used as a joint strategy of retailers as well as producers to emphasize quality and price differentiation, thereby increasing sales. Moreover, the study provides for the first time the outcomes of a brand new software “Visual Marketing REL”, highlighting its limits and positive elements.
Optical properties of laser sintered polyamide 12
Authors: Yuan Mengqi , Bourell David L. 
Published: June 2015

Purpose
– The purpose of this paper is to report selected optical properties of laser sintered polyamide 12 blank plates under different monochromatic and white light conditions and to apply these properties in production of laser sintered lithophanes.

Design/methodology/approach
– A UNICO 1201E spectrophotometer was used to measure the transmittance of laser sintered polyamide 12 plates as a function of plate thickness. Monochromatic light-emitting diodes were used to assess the wavelength dependence on the transmission and contrast as captured by a SONY DSC-W55 camera.

Findings
– The transmittance decreased with increasing plate thickness which varied significantly depending on the monochromatic wavelength. Highest transmission was observed using green light (525 nm) and poorest transmission was measured for yellow light (589 nm).

Research limitations/implications
– There is a limit to the amount of contrast obtained in polyamide lithophanes because the thickness of the plates is limited to less than about 5 mm. Greater thickness results in discernible topology on the lithophane which impairs the quality of the image.

Originality/value
– Light transmittance of polyamide 12 plates under different lighting conditions is reported and applied to optically defined laser sintered lithophanes.
Towards understanding of ultrasonic consolidation process with “process map”
Authors: Zhang Song , Yi Dalong , Zhang Hui , Zheng Lili , Zhang Yuduo , Yang Zhigang , Norfolk Mark 
Published: June 2015

Purpose
– The purpose of this paper is to identify the key parameters that control the bonding formation of foils by the ultrasonic consolidation (UC) process and to build the correlations among process operating conditions and key control parameters through the concept of “process map”.

Design/methodology/approach
– The concept of “process map” is proposed based on the diffusion bonding mechanism for the UC process, and numerical simulations have been applied to the UC process to predict peak temperature and plastic strain at the contact interface by considering a wide range of process operating conditions.

Findings
– This map reveals that the formation of bonding among foils by the UC process requires a good match between temperature and plastic deformation at the contact interface. This limits the process operating window to a narrow region in the strain – temperature coordinate system.

Originality/value
– This work has identified the underlying mechanism for bonding formation and the key control parameters of the UC process. The concept of “process map” for the UC process was developed, which allows the process optimization through two critical process control parameters of temperature and plastic strain at the contact interface instead of five operating conditions.
Low-energy drop weight performance of cellular sandwich panels
Authors: Yang Li , Harrysson Ola A , West II Harvey A , Cormier Denis R. , Park Chun , Peters Kara 
Published: June 2015

Purpose
– The aim of this study is to perform a comparative study on sandwich structures with several types of three-dimensional (3D) reticulate cellular structural core designs for their low-energy impact absorption abilities using powder bed additive manufacturing methods. 3D reticulate cellular structures possess promising potentials in various applications with sandwich structure designs. One of the properties critical to the sandwich structures in applications, such as aerospace and automobile components, is the low-energy impact performance.

Design/methodology/approach
– Sandwich samples of various designs, including re-entrant auxetic, rhombic, hexagonal and octahedral, were designed and fabricated via selective laser sintering (SLS) process using nylon 12 as material. Low-energy drop weight test was performed to evaluate the energy absorption of various designs. Tensile coupons were also produced using the same process to provide baseline material properties. The manufacturing issues such as geometrical accuracy and anisotropy effect as well as their effects on the performance of the structures were discussed.

Findings
– In general, 3D reticulate cellular structures made by SLS process exhibit significantly different characteristics under low-energy drop weight impact compared to the regular extruded honeycomb sandwich panels. A hexagonal sandwich panel exhibits the largest compliance with the smallest energy absorption ability, and an octahedral sandwich panel exhibits high stiffness as well as good impact protection ability. Through a proper geometrical design, the re-entrant auxetic sandwich panels could achieve a combination of high energy absorption and low response force, making it especially attractive for low-impact protection applications.

Originality/value
– There has been little work on the comparative study of the energy absorption of various 3D reticulate cellular structures to date. This work demonstrates the potential of 3D reticulate cellular structures as sandwich cores for different purposes. This work also demonstrates the possibility of controlling the performance of this type of sandwich structures via geometrical and process design of the cellular cores with powder bed additive manufacturing systems.
Colour polymorphism torn apart by opposing positive frequency‐dependent selection, yet maintained in space
Authors: Gordon Swanne P. , Kokko Hanna , Rojas Bibiana , Nokelainen Ossi , Mappes Johanna 
Published: June 2015

Summary

Polymorphic warning signals in aposematic species are enigmatic because predator learning and discrimination should select for the most common coloration, resulting in positive frequency‐dependent survival selection.

Here, we investigated whether differential mating success could create sufficiently strong negative frequency‐dependent selection for rare morphs to explain polymorphic (white and yellow) warning coloration in male wood tiger moths (Parasemia plantaginis).

We conducted an experiment in semi‐natural conditions where we estimated mating success for both white and yellow male moths under three different morph frequencies.

Contrary to expectations, mating success was positively frequency‐dependent: white morph males had high relative fitness when common, likewise yellow morph males had high relative fitness when instead they were common. We hence built a model parameterized with our data to examine whether polymorphism can be maintained despite two sources of positive frequency dependence. The model includes known spatial variation in the survival advantage enjoyed by the yellow morph and assumes that relative mating success follows our experimentally derived values. It predicts that polymorphism is possible under migration for up to approximately 20% exchange of individuals between subpopulations in each generation.

Our results suggest that differential mating success combined with spatial variation in predator communities may operate as a selection mosaic that prevents complete fixation of either morph.
Association Between Angiotensin‐Converting Enzyme 2 and Coronary Artery Calcification in Patients on Maintenance Hemodialysis Therapy
Authors: Zhang Qiankun , Sun Lina , Jin Lie 
Published: June 2015

AbstractWhile all mechanisms that contribute to the pathogenesis of coronary artery calcification (CAC) are unknown, angiotensin‐converting enzyme 2 (ACE2) may be involved in this process in maintenance hemodialysis (MHD) patients. The aim of this study was to investigate the association between ACE2 and CAC in patients on MHD therapy. Ninety patients on MHD therapy were involved in this prospective study. CAC was quantified by CAC score (CACs) using the Agatston method and a multi‐slice CT scanner. Univariate and multivariate logistic regression were used to analyze the association between ACE2 and CACs. In the univariate analysis, CACs positively correlated with ACE2 (r = 0.666, P < 0.001). After adjusting for age, sex, smoking, hypertension, body mass index, diabetes mellitus, and hyperlipidemia, ACE2 levels continued to significantly and independently predict the presence of CAC. ROC curve analysis showed that the serum ACE2 level can predict the extent of CAC. These findings indicate that elevated serum ACE2 may be involved in vascular calcification in patients receiving MHD therapy.
By the Markets, of the Markets, for the Markets? Technocratic Decision Making and the Hollowing Out of Democracy
Authors: Ruser Alexander 
Published: June 2015

AbstractThe global financial crisis of 2007 turned into a sovereign debt crisis that placed the economies within the EU in jeopardy. Despite hastily decided rescue packages, bailouts and far‐reaching reforms of economic governance in the EU the situation still looks grim in some Southern member states. In the course of these rescue attempts technocratic decision making at the European level and within the most crisis‐ridden countries became more influential. Instead of rethinking the economic system, political accountability shifted from citizens to markets in order to ‘fix the system’. The knowledge base informing political decision making remained largely intact, allowing a dominant, international advocacy coalition to impose reforms deemed ‘necessary’. The price to pay is a decline in trust in elected representatives and the threat to fall back behind even Schumpeterian‐style democracies.
Propagule pressure in the presence of uncertainty: extending the utility of proxy variables with hierarchical models
Authors: Drake D. Andrew R. , Casas‐Monroy Oscar , Koops Marten A. , Bailey Sarah A. 
Published: June 2015

SummarySpecies invasions depend on the abundance and rate at which organisms are introduced to new localities, known as propagule pressure. Due to the challenges of measuring propagule pressure, proxy variables are often used; however, untested proxy variables may obscure the role of propagule pressure vs. ecological factors that facilitate invasion, leading to uncertainty about the invasion process and confounding management response.To generate absolute estimates of propagule pressure and facilitate meaningful comparison among pathways of species introduction, we extend proxy variables by combining ecological and global trade data with hierarchical statistical models. We derive absolute propagule pressure with probability distribution functions (propagule size: the probability of introducingnpropagules per event; and overall propagule pressure: the probability of introducingnpropagules per year) and, based on these projections, evaluate the performance of ballast water volume (m3) as a common proxy variable.Hindcast accuracy of ballast water volume was low but strongly scale‐dependent, exhibiting poor accuracy (R2 = 0·058) at small scales and only marginal accuracy at large scales (overallR2 = 0·169). As a result, conclusions about propagule pressure are likely to be biased based on the ballast volume proxy, as may be conclusions about species invasion when ballast water volume has been used. Irrespective of geographic pathway, estimated propagule sizes demonstrated extreme leptokurtosis and long right tails, with maximum values between 131‐fold and 2966‐fold greater than median values. These characteristics signify a subset of introduction events involving extreme propagule abundance that may provide opportunity to overcome Allee thresholds or marginal environmental conditions.Developing meaningful propagule supply functions is critical to resolve the role of propagule pressure within the invasion process and test hypotheses about species colonization at landscape scales. By joining absolute propagule pressure with existing theory about species extinction, the expected ecological outcome of environmental policy to manage propagule pressure can be estimated within a statistical framework.
Seeing and Holding Baby: Systematic Review of Clinical Management and Parental Outcomes After Stillbirth
Authors: Kingdon Carol , Givens Jennifer L. , O'Donnell Emer , Turner Mark 
Published: June 2015

AbstractBackgroundIn 2009 there were an estimated 2.6 million stillbirths worldwide. In the United States, a 2007 systematic review found little consensus about professional behaviors perceived by parents to be most helpful or most distressing. In the United Kingdom, a bereaved parents' organization has highlighted discordance between parental views and clinical guidelines that recommend clinicians do not encourage parents to see and hold their baby. The objective of this review was to identify and synthesize available research reporting parental outcomes relating to seeing and holding.MethodsWe undertook a systematic review. We included studies of any design, reporting parental experiences and outcomes. Electronic searches (PubMed and PsychINFO) were conducted in January 2014. Three authors independently screened and assessed the quality of the studies before abstracting data and undertaking thematic analysis.ResultsWe reviewed 741 records and included 23 studies (10 quantitative, 12 qualitative, and 1 mixed‐method). Twenty‐one studies suggested positive outcomes for parents who saw or held their baby. Increased psychological morbidity was associated with current pregnancy, choice not to see their baby, lack of time with their baby and/or insufficient mementos. Three themes were formulated “positive effects of contact within a traumatic life event,” “importance of role of health professionals,” and “impact on mothers and fathers: similarities and differences.”ConclusionsStillbirth is a risk factor for increased psychological morbidity. Parents seeing and holding their stillborn baby can be beneficial to their future well‐being. Since 2007, there has been a proliferation of studies that challenge clinical guidelines recommending that clinicians do not encourage parental contact.
Melanoma and non‐melanoma skin cancers in hairy cell leukaemia: a Surveillance, Epidemiology and End Results population analysis and the 30‐year experience at Memorial Sloan Kettering Cancer Center
Authors: Watts Justin M. , Kishtagari Ashwin , Hsu Meier , Lacouture Mario E. , Postow Michael A. , Park Jae H. , Stein Eytan M. , Teruya‐Feldstein Julie , Abdel‐Wahab Omar , Devlin Sean M. , Tallman Martin S. 
Published: June 2015

SummaryFew studies have examined melanoma and non‐melanoma skin cancer (NMSC) incidence rates after a diagnosis of hairy cell leukaemia (HCL). We assessed 267 HCL patients treated at Memorial Sloan Kettering Cancer Center (MSKCC) and Surveillance, Epidemiology and End Results (SEER) data for melanoma and NMSC incidence rates after HCL. Incidence data from MSKCC patients demonstrated a 10‐year combined melanoma and NMSC skin cancer rate of 11·3%, melanoma 4·4% and NMSC 6·9%. Molecular analysis of skin cancers from MSKCC patients revealed activating RAS mutations in 3/9 patients, including one patient with melanoma. Of 4750 SEER patients with HCL, 55 (1·2%) had a subsequent diagnosis of melanoma. Standardized incidence ratios (SIRs) did not show that melanoma was more common in HCL patients versus the general population (SIR 1·3, 95% CI 0·78–2·03). Analysis of SEER HCL patients diagnosed before and after 1990 (approximately before and after purine analogue therapy was introduced) showed no evidence of an increased incidence after 1990. A better understanding of any potential association between HCL and skin cancer is highly relevant given ongoing trials using BRAF inhibitors, such as vemurafenib, for relapsed HCL, as RAS‐mutant skin cancers could be paradoxically activated in these patients.
Papillary Tumor of the Pineal Region: A Distinct Molecular Entity
Authors: Heim Stephanie , Sill Martin , Jones David T.W. , Vasiljevic Alexandre , Jouvet Anne , Fèvre‐Montange Michelle , Wesseling Pieter , Beschorner Rudi , Mittelbronn Michel , Kohlhof Patricia , Hovestadt Volker , Johann Pascal , Kool Marcel , Pajtler Kristian W. , Korshunov Andrey , Ruland Vincent , Sperveslage Jan , Thomas Christian , Witt Hendrik , von Deimling Andreas , Paulus Werner , Pfister Stefan M. , Capper David , Hasselblatt Martin 
Published: June 2015

AbstractPapillary tumor of the pineal region (PTPR) is a neuroepithelial brain tumor, which might pose diagnostic difficulties and recurs often. Little is known about underlying molecular alterations. We therefore investigated chromosomal copy number alterations, DNA methylation patterns and mRNA expression profiles in a series of 24 PTPRs. Losses of chromosome 10 were identified in all 13 PTPRs examined. Losses of chromosomes 3 and 22q (54%) as well as gains of chromosomes 8p (62%) and 12 (46%) were also common. DNA methylation profiling using Illumina 450k arrays reliably distinguished PTPR from ependymomas and pineal parenchymal tumors of intermediate differentiation. PTPR could be divided into two subgroups based on methylation pattern, PTPR group 2 showing higher global methylation and a tendency toward shorter progression‐free survival (P = 0.06). Genes overexpressed in PTPR as compared with ependymal tumors included SPDEF, known to be expressed in the rodent subcommissural organ. Notable SPDEF protein expression was encountered in 15/19 PTPRs as compared with only 2/36 ependymal tumors, 2/19 choroid plexus tumors and 0/23 samples of other central nervous system (CNS) tumor entities. In conclusion, PTPRs show typical chromosomal alterations as well as distinct DNA methylation and expression profiles, which might serve as useful diagnostic tools.
Layered approach with autogenous bone and bone substitute for ridge augmentation on implant dehiscence defects in dogs
Authors: Lee In‐Kyeong , Lim Hyun‐Chang , Lee Jung‐Seok , Hong Ji‐Youn , Choi Seong‐Ho , Jung Ui‐Won 
Published: June 2015

AbstractObjectivesThis study compared the efficacies of different layered approaches using autogenous bone and synthetic bone substitute for ridge augmentation on implant dehiscence defects in dogs.Materials and methodsRight mandibular second, third, and fourth premolars and the first molar were extracted, followed by standardized one‐wall defect preparation in five dogs. After a healing period of 12 weeks, three implants (Implantium®) were installed. Each of the three implant dehiscence defects was grafted with a different material as follows: (i) synthetic bone substitute combined with collagen (SBC; SBC group), (ii) inner autogenous bone layer and outer SBC layer (IAB group), and (iii) inner SBC layer and outer autogenous bone layer (OAB group). The grafted sites were covered with a resorbable collagen membrane. Quantitative and qualitative analyses of the subsequent bone regeneration were performed at 12 weeks postoperatively.ResultsThe dome‐like augmented shape was relatively well maintained in the IAB and OAB groups, while the graft particles in the SBC group were dispersed. The bone‐to‐implant contact values tended to be significantly higher in the OAB group (49.51%) than in the SBC (36.58%) group. The amounts of newly formed bone within an area designated as 1 × 3 mm (width × height) from the implant platform in the IAB, OAB, and SBC groups were 35.59%, 28.10%, and 16.71%, respectively.ConclusionApplication of the layered approach using autogenous bone and synthetic biomaterial resulted in substantial new bone formation and volume maintenance on implant dehiscence defects, irrespective of the position of the autogenous bone layer.
Severe drug‐induced skin reactions: clinical features, diagnosis, etiology, and therapy
Authors: Paulmann Maren , Mockenhaupt Maja 
Published: June 2015

SummaryDrugs can induce severe skin reactions that differ in clinical presentation, prognosis, and therapy. The spectrum of these reactions not only includes bullous reactions such as Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and generalized bullous fixed drug eruption (GBFDE) but also acute generalized exanthematous pustulosis (AGEP) and drug reaction with eosinophilia and systemic symptoms (DRESS). If AGEP or DRESS is suspected, the diagnosis should be confirmed by thorough clinical examination, a skin biopsy, and specific laboratory tests. Crucial for the patient's prognosis, the causative agent should be rapidly identified and discontinued. It is therefore important to know the most frequent triggers of severe drug reactions, some of which may induce various reaction patterns. Depending on the clinical diagnosis, symptomatic and adequate supportive therapy, as well as systemic immunomodulatory treatments are used. The prognosis in SJS/TEN is often poor and depends on the patient's age and underlying conditions as well as the extent of skin detachment. The prognosis of GBFDE is somewhat better, but recurrences may lead to more severe disease manifestations. In DRESS, protracted and recurrent courses have been described, whereas AGEP usually resolves without problems.