bluuebunny/crossref_metadata_2025_split huggingface dataset:
Paper No 8.3: Nanoimprinted Organic Electrochemical Transistors
Authors: Rothländer T. , Gold H. , Haase A. , Jakopic G. , Hartmann P. , Stadlober B. , Hütter P. C. 
Published: November 2013

AbstractThe use of organic molecular and polymer materials in circuitry has received considerable attention during the last years. These multifunctional materials enable the low‐cost production of simple designed organic electronic devices and logic circuits that are driven at low voltages. We report on electrochemical transistors (ECTs) structured by nanoimprint lithography (NIL). With this technique it is possible to fabricate transistors with critical dimensions in the sub‐micrometer regime, which should lead to higher switching speed and improved overall transistor performance.
Paper No 9.2: Experimental and Theoretical Modeling of Liquid Crystal Orientation on Aligning Film Surfaces
Authors: Belyaev Victor V. 
Published: November 2013

AbstractRecent experimental and theoretical results in area of liquid crystal (LC) aligning coatings are described. Parameters of the organosilicon compounds (OC) films for LC alignment have been realized that allow their application in the LCD. Green and cheap OC synthesis technologies have been developed. Method of simulation of the LC alignment on solid film has been developed that will allow predicting the aligning substance molecular structure for different LC molecules. In addition, optical properties of cells with sophisticated distribution of local optical axes of birefringent materials have been calculated that allow creating new optical compensators and LCD with wide viewing angles.
Paper No 11.1: Enhanced Pixel Technology for Holographic Projection Displays
Authors: Wilkinson T. D. , Chen R. , Butt H. 
Published: November 2013

AbstractHolography is one of the best ways of making a truly 3D display, but there are limitations due to the hologram technology such as the traditional LCD square pixel. We explore other possibilities based around nanotechnology, which allow submicron pixel pitches and break the restrictions of pixel boundaries and geometries.
Paper No 11.4: High‐Performance Large‐Area Projected Capacitive Touch Screen Using Double Layered Metal Mesh Electrodes
Authors: Ono Takeshi , Agari Masafumi , Mori Seiichiro , Imamura Takuji , Miyayama Takashi , Nakamura Tatsuya , Nakagawa Naoki 
Published: November 2013

AbstractWe have developed a new high performance projected capacitive touch screen which has double layered metal mesh electrodes. By using high conductive metal electrodes and optimizing the mesh design, high sensitive 15‐inch diagonal self capacitance touch screen and 8‐inch diagonal mutual capacitance touch screen, both of which are optically bonded to LCD modules, have been developed.
Paper No 13.2: Experimenting with Backlights
Authors: Travis Adrian 
Published: November 2013

AbstractThe conventional LCD was designed around fluorescent backlights but bright LEDs make different compromises possible. A suitably designed light‐guide lets us collimate the light then diffuse it over a precise range of angles, eliminating waste. There is the potential to scan the direction of collimation in the horizontal so that light is always concentrated to the head of the user, but users also move in the vertical and forward and back. I will discuss more advanced backlight concepts, which would let us concentrate rays into the users' eyes whatever their position, thus eliminating unseen light and reducing the optical power budget to near zero.
Paper No 14.3: Ultra‐Large Field of View and High‐Magnification Imaging Video Colorimeter
Authors: Boher Pierre , Bignon Thierry Leroux Thibault , Collomb‐Patton Véronique 
Published: November 2013

AbstractELDIM proposes XScope, the first video colorimeter with ultra large field of view and high magnification. Thanks to a unique microscope objective with ∼1 cm2 field of view and a spatial resolution around 1.5 μm, it allows luminance and color measurements on the entire surface of micro displays and the extraction of the color and luminance of each subpixel for calibration and quality control purpose.
Paper No 15.3: Large High‐Definition Multiview Display System With Wide Observation Area
Authors: Kawakami Tohru , Ishinabe Takahiro , Sasai Mutsumi , Kano Mitsuru , Suzuki Yoshito , Nasu Senshi , Uchida Tatsuo , Ozawa Shiro , Mieda Satoshi , Yao Yasuhiro , Date Munekazu , Takada Hideaki 
Published: November 2013

AbstractWe have developed a large high‐definition multiview projection display using a novel double‐sided lenticular lens, Fresnel lens and multiple projectors. By forming the magnified images of iris planes of the projectors side‐by‐side in space, we realized high luminance uniformity, wide observation area, while keeping crosstalk of the image to a minimum.
Paper No 17.3: Disparity Selection in Stereoscopic Image
Authors: Kim Jaehong , Shin Hongsoep , Seo Woongjin , Lee Don Gyou , Shin Kwanghoon , Park Jongjin , Lim Moojong 
Published: November 2013

AbstractThree‐dimensional (3D) display devices provide a more realistic experience of entertainment. A great deal of research has been doing to enhance 3D image quality and reduce visual fatigue of stereoscopic display. One of the important considering factors of 3D research is the disparity which is, in general, defined the positional difference between left and right images. The definition is, however, too ambiguous to fix the disparity from various 3D contents. A new definition and a classification method, therefore, are suggested in this study. Furthermore, the validity of the suggested method was verified from a visual assessment.
Paper No 19.2: Large‐Area Printed Transparent Electrodes for Flexible Organic Light‐Emitting Diodes
Authors: Wang Xuhua , Levermore Peter A. , Ramon Miguel C. , Voigt Monika , Belton Colin , Lofts Edwards , Cheung Cora , Stavrinou Paul , Nelson Jenny , Bradley Donal D. C. 
Published: November 2013

AbstractWe report large area gravure‐printed flexible and transparent polymer electrodes for plastic electronics and in particular their application in organic light‐emitting diodes (OLEDs) for displays and lighting applications. The polymer electrodes are prepared from vapour‐phase polymerised poly(3,4‐ethylene‐dioxythiophene) (VPP‐PEDOT). Gravure printing has been selected for this work owing to its proven compatibility with low‐cost and high volume roll‐to‐roll manufacturing. The printed VPP‐PEDOT thin films were characterised for their conductivity, transparency, work function and surface roughness. After optimisation of printed VPP‐PEDOT thin film transparent electrodes, large area ITO free OLEDs were demonstrated.
Paper No 19.3: Back‐Channel‐Etch Process Flow for a‐IGZO TFTs
Authors: Nag Manoj , Steudel Soeren , Chasin Adrian , Myny Kris , Rockele Maarten , Bhoolokam Ajay , Willegems Myriam , Smout Steve , Vicca Peter , Ameys Marc , Schols Sarah , Cheyns David , Genoe Jan , van der Steen Jan‐Laurens , Tempelaars Karin , Groeseneken Guido , Heremans Paul 
Published: November 2013

AbstractIn this study, the authors report high‐quality amorphous Indium‐Gallium‐Zinc‐Oxide (a‐IGZO) thin film transistors (TFTs) fabricated using a new back‐channel‐etch (BCE) process flow on Polyethylene Naphthalate (PEN) foil. The BCE flow allows a better scalability of TFTs for high‐resolution backplanes and related circuits. The maximum processing temperature was limited to less than 165oC in order to ensure good overlay accuracy (< 1µm) on foil. The presented process flow differs from to previously reported by defining the Mo S/D contacts by dry etch prior to a‐IGZO patterning. The TFTs show good electrical performance, including field‐effect mobilities in the range of 15.0cm2/(V.s), sub‐threshold slopes of 0.3V/decade and off‐currents <1.0pA on foil. Finally, the applicability of this new BCE process flow was demonstrated for TFT backplane driving a 32 x 32 active‐matrix organic light‐emitting diode (AMOLED) display.
Paper No P18: A Novel Method of Decision on the Optimal Display Gamma Curve Through the Characteristics of Display and Image
Authors: Lee Min Woo , Park Hyun Hee , Kang Ha Seung A , Bae Hak Gyun , Jang Seul Ki , Kim Jong Ho , Yeom Jee Young 
Published: November 2013

AbstractThe purpose of this study is to propose a novel method of optimal display gamma curve using display performance and image contents characteristic which is displayed on the device. For the aspect of the display performance, image quality is a complex task because it is a consequence of interaction of quality attribute. However, the gamma attribute is the most dominant aspect for the display quality. Applying the curve of optimal display gamma can improve both the quality of displayed image and visibility for the environment of mobile device usage. In this study, we suggest a method of optimal display gamma curve based on display performance, image contents characteristic, and the environment of mobile device usage.
Dominant Role of Peroxiredoxin/JNK Axis in Stemness Regulation During Neurogenesis from Embryonic Stem Cells
Authors: Kim Sun-Uk , Park Young-Ho , Kim Jin-Man , Sun Hu-Nan , Song In-Sung , Huang Song Mei , Lee Sang-Hee , Chae Jung-Il , Hong Su , Sik Choi Sung , Choi Seung-Cheol , Lee Tae-Hoon , Kang Sang Won , Rhee Sue Goo , Chang Kyu-Tae , Lee Sang Ho , Yu Dae-Yeul , Lee Dong-Seok 
Published: November 2013

Abstract
Redox balance has been suggested as an important determinant of “stemness” in embryonic stem cells (ESCs). In this study, we demonstrate that peroxiredoxin (Prx) plays a pivotal role in maintenance of ESC stemness during neurogenesis through suppression of reactive oxygen species (ROS)-sensitive signaling. During neurogenesis, Prx I and Oct4 are expressed in a mutually dependent manner and their expression is abruptly downregulated by an excess of ROS. Thus, in Prx I−/− or Prx II−/− ESCs, rapid loss of stemness can occur due to spontaneous ROS overload, leading to their active commitment into neurons; however, stemness is restored by the addition of an antioxidant or an inhibitor of c-Jun N-terminal kinase (JNK). In addition, Prx I and Prx II appear to have a tight association with the mechanism underlying the protection of ESC stemness in developing teratomas. These results suggest that Prx functions as a protector of ESC stemness by opposing ROS/JNK cascades during neurogenesis. Therefore, our findings have important implications for understanding of maintenance of ESC stemness through involvement of antioxidant enzymes and may lead to development of an alternative stem cell-based therapeutic strategy for production of high-quality neurons in large quantity. Stem Cells 2014;32:998–1011
Mesenchymal Stem Cells Cancel Azoxymethane-Induced Tumor Initiation
Authors: Nasuno Masanao , Arimura Yoshiaki , Nagaishi Kanna , Isshiki Hiroyuki , Onodera Kei , Nakagaki Suguru , Watanabe Shuhei , Idogawa Masashi , Yamashita Kentaro , Naishiro Yasuyoshi , Adachi Yasushi , Suzuki Hiromu , Fujimiya Mineko , Imai Kohzoh , Shinomura Yasuhisa 
Published: November 2013

Abstract
The role of mesenchymal stem cells (MSCs) in tumorigenesis remains controversial. Therefore, our goal was to determine whether exogenous MSCs possess intrinsic antineoplastic or proneoplastic properties in azoxymethane (AOM)-induced carcinogenesis. Three in vivo models were studied: an AOM/dextran sulfate sodium colitis-associated carcinoma model, an aberrant crypt foci model, and a model to assess the acute apoptotic response of a genotoxic carcinogen (AARGC). We also performed in vitro coculture experiments. As a result, we found that MSCs partially canceled AOM-induced tumor initiation but not tumor promotion. Moreover, MSCs inhibited the AARGC in colonic epithelial cells because of the removal of O6-methylguanine (O6MeG) adducts through O6MeG-DNA methyltransferase activation. Furthermore, MSCs broadly affected the cell-cycle machinery, potentially leading to G1 arrest in vivo. Coculture of IEC-6 rat intestinal cells with MSCs not only arrested the cell cycle at the G1 phase, but also induced apoptosis. The anti-carcinogenetic properties of MSCs in vitro required transforming growth factor (TGF)-β signaling because such properties were completely abrogated by absorption of TGF-β under indirect coculture conditions. MSCs inhibited AOM-induced tumor initiation by preventing the initiating cells from sustaining DNA insults and subsequently inducing G1 arrest in the initiated cells that escaped from the AARGC. Furthermore, tumor initiation perturbed by MSCs might potentially dysregulate WNT and TGF-β-Smad signaling pathways in subsequent tumorigenesis. Obtaining a better understanding of MSC functions in colon carcinogenesis is essential before commencing the broader clinical application of promising MSC-based therapies for cancer-prone patients with inflammatory bowel disease. Stem Cells 2014;32:913–925
Low brain CB1 receptor occupancy by a second generation CB1 receptor antagonist TM38837 in comparison with rimonabant in nonhuman primates: A PET study
Authors: Takano Akihiro , Gulyás Balázs , Varnäs Katarina , Little Paul Brian , Noerregaard Pia K. , Jensen Niels Ole , Elling Christian e. , Halldin Christer 
Published: November 2013

ABSTRACTBoth central and peripheral cannabinoid receptor type 1 (CB1R) have been considered to be among the key targets for obesity treatment. First generation CB1R antagonists/inverse agonists such as rimonabant and taranabant exhibited severe CNS side effects such as anxiety and depression, which are considered to be related to the compounds' ability to access central CB1R. Recently, several compounds have been developed as second generation antagonists with a profile of restriction to peripheral CB1R. We evaluated the distribution of TM38837, a second generation CB1R antagonist, using brain and whole body PET in three cynomolgus monkeys, and established the relationship between CB1R occupancy and dose/plasma concentration of TM38837 in comparison with rimonabant. A brain PET study was performed using [11C]MePPEP, a PET radioligand for CB1R, to evaluate the brain CB1R occupancy of TM38837 at various plasma concentrations in comparison with rimonabant at known efficacious plasma concentrations. A whole body PET study was performed to investigate the change of peripheral distribution of [11C]MePPEP by TM38837 administration, which indirectly estimated the effects to the peripheral CB1R by TM38837. CB1R occupancy by both TM38837 and rimonabant increased in a dose/plasma concentration‐dependent manner. However, in vivo affinity by plasma level was more than 100 times lower for TM38837. Peripherally, [11C]MePPEP accumulation decreased in gall bladder and brown adipose tissue by TM38837 administration. TM38837 showed rather lower CB1R occupancy than rimonabant at the expected therapeutic plasma level, which is expected to reduce CNS side effects in clinical situations. Further clinical development of TM38837 is warranted. Synapse 68:89–97, 2014. © 2013 Wiley Periodicals, Inc.
Black bear density in Glacier National Park, Montana
Authors: Stetz Jeff B. , Kendall Katherine C. , Macleod Amy C. 
Published: November 2013

ABSTRACTWe report the first abundance and density estimates for American black bears (Ursus americanus) in Glacier National Park (NP), Montana, USA. We used data from 2 independent and concurrent noninvasive genetic sampling methods—hair traps and bear rubs—collected during 2004 to generate individual black bear encounter histories for use in closed population mark–recapture models. We improved the precision of our abundance estimate by using noninvasive genetic detection events to develop individual‐level covariates of sampling effort within the full and one‐half mean maximum distance moved (MMDM) from each bear's estimated activity center to explain capture probability heterogeneity and inform our estimate of the effective sampling area. Models including the one‐half MMDM covariate received overwhelming Akaike's Information Criterion support suggesting that buffering our study area by this distance would be more appropriate than no buffer or the full MMDM buffer for estimating the effectively sampled area and thereby density. Our model‐averaged super‐population abundance estimate was 603 (95% CI = 522–684) black bears for Glacier NP. Our black bear density estimate (11.4 bears/100 km2, 95% CI = 9.9–13.0) was consistent with published estimates for populations that are sympatric with grizzly bears (U. arctos) and without access to spawning salmonids. Published 2013. This article is a U.S. Government work and is in the public domain in the USA
Combining human error verification and timing analysis: a case study on an infusion pump
Authors: Rukšėnas Rimvydas , Curzon Paul , Blandford Ann , Back Jonathan 
Published: November 2013

Abstract

The design of a human–computer interactive system can be unacceptable for a range of reasons. User performance concerns, for example the likelihood of user errors and time needed for a user to complete tasks, are important areas of consideration. For safety-critical systems it is vital that tools are available to support the analysis of such properties before expensive design commitment has been made. In this work, we give a unified formal verification framework for integrating two kinds of analysis: (1) predicting bounds for task-completion times via exhaustive state-space exploration, and (2) detecting user-error related design issues. The framework is based on a generic model of cognitively plausible behaviour that captures assumptions about cognitive behaviour decided through a process of interdisciplinary negotiation. Assumptions made in an analysis, including those relating to the performance consequences of users
recovering
from likely errors, are also investigated in this framework. We further present a novel way of exploring the consequences of cognitive mismatches, on both correctness and performance grounds. We illustrate our analysis approach with a realistic medical device scenario: programming an infusion pump. We explore an initial pump design and then two variations based on features found in real designs, illustrating how the approach identifies both timing and human error issues.
Genome-guided discovery of diverse natural products from Burkholderia sp.
Authors: Liu Xiangyang , Cheng Yi-Qiang 
Published: November 2013

Abstract
Burkholderia species have emerged as a new source of diverse natural products. This mini-review covers all of the natural products discovered in recent years from Burkholderia sp. by genome-guided approaches—these refer to the use of bacterial genome sequence as an entry point for in silico structural prediction, wet lab experimental design, and execution. While reliable structural prediction based on cryptic biosynthetic gene cluster sequence was not always possible due to noncanonical domains and/or module organization of a deduced biosynthetic pathway, a molecular genetic method was often employed to detect or alter the expression level of the gene cluster to achieve an observable phenotype, which facilitated downstream natural product purification and identification. Those examples of natural product discovery from Burkholderia sp. provide practical guidance for future exploration of Gram-negative bacteria as a new source of natural products.
An Exploration of the Experience of Huntington's Disease in Family Dyads: An Interpretative Phenomenological Analysis
Authors: Maxted Caroline , Simpson Jane , Weatherhead Stephen 
Published: November 2013

AbstractHuntington's disease (HD) is a hereditary, late onset, neurodegenerative disorder. Children of affected parents have a 50 % chance of inheriting HD. Research into the psychological consequences of HD for the family has focussed on individual family members, but little is known about the ways in which its impact is jointly experienced by members of these families. This is particularly important due to the hereditary nature of HD. To address this, the current study examined the experiences of dyads within affected families. Seven parent/adult child dyads were interviewed jointly about their experiences and relationships with their family and each other and interpretative phenomenological analysis was used to analyse the resultant data. Identified themes were: “A spectre hanging over us”: HD as a presence within the family, “Us against the world”: Protection, knowledge and control, and “That could be me in 50 years”: Cyclical changes in identity and role. These findings are examined in relation to previous research and indicate the need for an increased understanding of the needs of HD families. Clinical implications and suggestions for further research are discussed.
Rayleigh–Bénard instability generated by a diffusion flame
Authors: Pearce P. , Daou J. 
Published: November 2013

AbstractWe investigate the Rayleigh–Bénard convection problem within the context of a diffusion flame formed in a horizontal channel where the fuel and oxidizer concentrations are prescribed at the porous walls. This problem seems to have received no attention in the literature. When formulated in the low-Mach-number approximation the model depends on two main non-dimensional parameters, the Rayleigh number and the Damköhler number, which govern gravitational strength and reaction speed respectively. In the steady state the system admits a planar diffusion flame solution; the aim is to find the critical Rayleigh number at which this solution becomes unstable to infinitesimal perturbations. In the Boussinesq approximation, a linear stability analysis reduces the system to a matrix equation with a solution comparable to that of the well-studied non-reactive case of Rayleigh–Bénard convection with a hot lower boundary. The planar Burke–Schumann diffusion flame, which has been previously considered unconditionally stable in studies disregarding gravity, is shown to become unstable when the Rayleigh number exceeds a critical value. A numerical treatment is performed to test the effects of compressibility and finite chemistry on the stability of the system. For weak values of the thermal expansion coefficient $\alpha $, the numerical results show strong agreement with those of the linear stability analysis. It is found that as $\alpha $ increases to a more realistic value the system becomes considerably more stable, and also exhibits hysteresis at the onset of instability. Finally, a reduction in the Damköhler number is found to decrease the stability of the system.
A BIRDIE THAT IS NOT A BIRDIE IN PYTHON'S AGEN (FR. 1 = ATH. 13.595F)
Authors: Janko Richard 
Published: November 2013

In Python's comic satyr play Agen (perhaps actually written by Alexander of Macedon) Harpalus, Alexander's errant treasurer, is mocked for erecting costly buildings left and right to honour his dead lover, the notorious prostitute Pythionice:ἔστιν δ’ ὅπου μὲν ὁ κάλαμος πέϕυχ’ ὅδε†ϕέτωμ’ ἄορνον, οὑξ ἀριστερᾶς δ’ ὅδεπόρνης ὁ κλεινὸς ναός, ὃν δὴ Παλλίδηςτεύξας κατέγνω διὰ τὸ πρᾶγμ’ αὑτοῦ ϕυγήν.(TrGF 91 F 1. 1–4)1–2 πέϕυκε· ὁ δ’ εϕετωμα ορνον Athenaei cod. A: ὅδε scr. Dindorf, ἄορνον Fiorillo †ϕέτωμ’ vox desperata: ϕάτνωμ’ Fiorillo, ἕλωμ’ Meineke, πέτρωμ’ Pezopulus, ϕλέωμ’ A. von Blumenthal, στόμωμ’ Erbse, ϕηγὼν Friebel
GALEN SOTTO VOCE: METH. MED. 13.6 (10.892.5–7 K)
Authors: Horsley G.H.R. 
Published: November 2013

Late in the second part (books 7–14) of the Therapeutikê methodos, which Galen was completing after a twenty-year gap since beginning the work as a whole, the text in Kühn (and in B = British Library Add. MS 6898 [xii cent.], at least) includes a comment which looks like a Galenic aside made parenthetically to himself while dictating. The sentence reads: ἐκεῖθεν οὖν αὐτὰ μεταφέρειν ἐνταῦθα σκοπούμενον ὅτῳ βέλτιον ἐξ αὐτῶν (so MS B, superior to K's ἑαυτῶν) χρῆσθαι, ‘So (I ought) to consider transferring them (namely, my discussion on the treatment of kakokhymia) to here from there (i.e. in the section on prophylaxis in the De san. tuenda) to make better use of them’. The rendering in the new Loeb volume 3, p. 345 is not clear.