bluuebunny/crossref_metadata_2025_split huggingface dataset:
Abnormal adaptation over time of motor network recruitment in multiple sclerosis patients with fatigue
Authors: Rocca Maria A , Meani Alessandro , Riccitelli Gianna C , Colombo Bruno , Rodegher Mariaemma , Falini Andrea , Comi Giancarlo , Filippi Massimo 
Published: October 2015

Objectives: Using functional magnetic resonance imaging (fMRI) during a motor task, we investigated the functional correlates of central fatigue in multiple sclerosis (MS), and adaptation of motor network recruitment during a prolonged effort. Methods: Motor fMRI was obtained from 79 MS patients (50 fatigued (F), 29 non-fatigued (nF)) and 26 matched healthy controls (HC). Cognitive and physical fatigue were rated using the Modified Fatigue Impact Scale (MFIS). Results: Compared to HC and nF patients, F-MS patients experienced reduced activations of the left middle temporal gyrus, left supplementary motor area (SMA), bilateral superior frontal gyrus, left postcentral gyrus and basal ganglia regions. They also showed increased activation of the right middle frontal gyrus (MFG). Time-modulation analysis showed a reduced activity of the SMA and right precentral gyrus, and increased activity of the basal ganglia in HC. Such a trend was impaired in F-MS patients. In MS patients, increased MFG activity was related to MFIS scores. Physical MFIS score was related to a reduced recruitment of the right thalamus and SMA. Conclusions: Abnormalities and impaired timing of activation between different areas of the motor and executive networks occur in F-MS patients. The dysfunction of critical cortical areas contributes to the occurrence of central fatigue.
Analysis of suitability of elastomeric woven tape for strain sensor application and measurement of elbow angle
Authors: Sonica K , Naveen VS , Thilagavathi G 
Published: October 2015

Textile-based body worn sensors are preferred due to its comfortability for continuous monitoring of the body vital signs and kinematics. This research discusses the development and characterization of elastomeric tape for strain sensor application and is used for the measurement of elbow angle. The stress strain properties of commercially available elastomeric tapes have been analyzed for the selection of suitable specifications of elastomeric tape. The actual sensor has been developed with the help of narrow width tape loom by introducing the silver-coated nylon yarn in the middle of the tape structure. The effect of linear density of conductive yarn and number and strands of conductive threads used on sensitivity of the sensor was studied. The repeatability of the developed sensor was characterized by cyclic testing using Zwick tensile tester. Based on the results, polyester yarns were used as base threads along with rubber threads for the sensor development. It was found that sensor developed using finer yarn with six conductive threads has higher sensitivity. The developed sensor was integrated on to elbow sleeve and elbow angle measurement was done. The results of the developed tape sensor have been compared with the hospital goniometer for 10 male subjects. The results showed that the developed tape sensor is suitable for measuring the elbow angles up to 150°.
Manual aspiration thrombectomy using the Penumbra catheter in patients with acute M1 occlusion: A single-center study
Authors: Kim Yong Seek , Kwak Hyo Sung , Chung Gyung Ho , Hwang Seung Bae 
Published: October 2015

Purpose The efficacy and safety of aspiration thrombectomy using Penumbra in acute occlusion of intracranial artery have been proved in many previous studies. Our study aimed to retrospectively assess the efficacy and safety of a manual aspiration thrombectomy using Penumbra in patients with M1 occlusion. Materials and methods We conducted a retrospective review of 70 patients who underwent manual aspiration thrombectomy using Penumbra catheters for treatment of M1 occlusion between January 2012 and December 2014. We evaluated immediate angiographic results and clinical outcomes through review of patient electronic medical records. Results Male was the dominant sex in this study (M:F = 38:32) and median age was 72 (age range, 36–91). The rate of successful recanalization (TICI grade ≥2 b) was 91.4% (64/70). The successful recanalization rate by single Penumbra was 82.9% (58/70). Six patients were treated in combination with Solitaire stent. Median NIHSS score was 11 (range, 4–20) at admission and was 3 (range 0–23) at discharge. Favorable clinical outcomes (mRS score at three months ≤2) were seen in 42 patients (60%). Two patients were observed to have subarachnoid hemorrhage after the procedure. Another two patients died related to massive symptomatic hemorrhage, brain edema and herniation in the hospital. Conclusion Manual aspiration thrombectomy appears to be safe and is capable of achieving a high rate of successful recanalization and favorable clinical outcomes in patients with M1 occlusion.
Telomere shortening in enterocytes of patients with uncontrolled acute intestinal graft-versus-host disease
Authors: Hummel Sebastian , Ventura Ferreira Mónica S. , Heudobler Daniel , Huber Elisabeth , Fahrenkamp Dirk , Gremse Felix , Schmid Karin , Müller-Newen Gerhard , Ziegler Patrick , Jost Edgar , Blasco Maria A. , Brümmendorf Tim H. , Holler Ernst , Beier Fabian 
Published: October 2015

Key Points
Enterocytes of patients with aGVHD undergo dramatic telomere shortening (∼200 bp/wk). Telomere loss with subsequent replicative exhaustion might provide a mechanism for refractory gut GVHD.
KIR2DL5B genotype predicts outcomes in CML patients treated with response-directed sequential imatinib/nilotinib strategy
Authors: Yeung David T. , Tang Carine , Vidovic Ljiljana , White Deborah L. , Branford Susan , Hughes Timothy P. , Yong Agnes S. 
Published: October 2015

Key Points
KIR2DL5B is associated with poor molecular response and transformation-free survival in CML patients enrolled to the TIDEL-II study. KIR genotyping would select out high risk CML patients at baseline and allow better targeting of novel interventions.
Fludarabine, cyclophosphamide, and rituximab treatment achieves long-term disease-free survival in IGHV-mutated chronic lymphocytic leukemia
Authors: Thompson Philip A. , Tam Constantine S. , O’Brien Susan M. , Wierda William G. , Stingo Francesco , Plunkett William , Smith Susan C. , Kantarjian Hagop M. , Freireich Emil J. , Keating Michael J. 
Published: October 2015

Key Points
FCR-treated chronic lymphocytic leukemia patients with mutated IGHV gene achieve long-term PFS, with a plateau on the PFS curve. MRD-negativity posttreatment is highly predictive of long-term PFS, particularly in patients with mutated IGHV gene.
Suicides during pregnancy and 1 year postpartum in Sweden, 1980–2007
Authors: Esscher Annika , Essén Birgitta , Innala Eva , Papadopoulos Fotios C. , Skalkidou Alkistis , Sundström-Poromaa Inger , Högberg Ulf 
Published: October 2015

BackgroundAlthough the incidence of suicide among women who have given birth during the past 12 months is lower than that of women who have not given birth, suicide remains one of the most common causes of death during the year following delivery in high-income countries, such as Sweden.AimsTo characterise women who died by suicide during pregnancy and postpartum from a maternal care perspective.MethodWe traced deaths (n= 103) through linkage of the Swedish Cause of Death Register with the Medical Birth and National Patient Registers. We analysed register data and obstetric medical records.ResultsThe maternal suicide ratio was 3.7 per 100 000 live births for the period 1980–2007, with small magnitude variation over time. The suicide ratio was higher in women born in low-income countries (odds ratio 3.1 (95% CI 1.3–7.7)). Violent suicide methods were common, especially during the first 6 months postpartum. In all, 77 women had received psychiatric care at some point, but 26 women had no documented psychiatric care. Antenatal documentation of psychiatric history was inconsistent. At postpartum discharge, only 20 women had a plan for psychiatric follow-up.ConclusionsSuicide prevention calls for increased clinical awareness and cross-disciplinary maternal care approaches to identify and support women at risk.
A Hybrid Strategy for the Preparation of 13C-labeled High-mannose-type Oligosaccharides with Terminal Glucosylation for NMR Study
Authors: Zhu Tong , Yamaguchi Takumi , Satoh Tadashi , Kato Koichi 
Published: October 2015

Abstract
Stable isotopic labeling dramatically facilitates NMR studies of oligosaccharides. We previously established a method for overexpressing homogeneous high-mannose-type oligosaccharides with metabolic 13C labeling using genetically engineered yeast cells. To extend the applicability of this methodology, we combined it with chemoenzymatic synthesis using a specific glucosyl transferase. Our hybrid approach has enabled the production of a uniformly and selectively 13C-labeled dodecasaccharide with terminal glucosylation, a signal recognized by molecular chaperones, providing useful NMR tools for detailed conformational analyses.
Origin of the Hysteresis in I–V Curves for Planar Structure Perovskite Solar Cells Rationalized with a Surface Boundary-induced Capacitance Model
Authors: Cojocaru Ludmila , Uchida Satoshi , Jayaweera Piyankarage V V , Kaneko Shoji , Nakazaki Jotaro , Kubo Takaya , Segawa Hiroshi 
Published: October 2015

Abstract
For efficient hybrid solar cells based on organometal halide perovskites, the real origin of the I–V hysteresis became a big issue and has been discussed widely. In this study, simulated I–V curves of different equivalent circuit models were validated with experimental I–V curves of a planar perovskite solar cell with the power conversion efficiency (PCE) of 18.0% and 8.8% on reverse scan (from open circuit to short circuit) and forward scan (from short circuit to open circuit), respectively. We found that an equivalent circuit model with a series of double diodes, capacitors, shunt resistances, and single series resistance produces simulated I–V curves with large hysteresis matching with the experimentally observed curves. The electrical capacitances generated by defects due to the lattice mismatch at the TiO2/CH3NH3PbI3 and CH3NH3PbI3/spiro-OMeTAD interface are truly responsible for the hysteresis in perovskite solar cells.
Oxygen changes drive non-uniform scaling in Drosophila melanogaster embryogenesis
Authors: Kuntz Steven G. , Eisen Michael B. 
Published: October 2015

We previously demonstrated that, while changes in temperature produce dramatic shifts in the time elapsed duringDrosophila melanogasterembryogenesis, the relative timing of events within embryogenesis does not change. However, it was unclear if this uniform scaling is an intrinsic property of developing embryos, or if it is specific to thermal fluctuations. To investigate this, here we characterize the embryonic response to changes in oxygen concentration, which also impact developmental rate, using time-lapse imaging, and find it fundamentally different from the temperature response. Most notably, changes in oxygen levels drive developmental heterochrony, with the timing of several morphological processes showing distinct scaling behaviors. Gut formation is severely slowed by decreases in oxygen, while head involution and syncytial development are less impacted than the rest of development, and the order of several developmental landmarks is inverted at different oxygen levels. These data reveal that the uniform scaling seen with changes in temperature is not a trivial consequence of adjusting developmental rate. The developmental rate changes produced by changing oxygen concentrations dwarf those induced by temperature, and greatly impact survival. While extreme temperatures increase early embryo mortality, mild hypoxia increases arrest and death during mid-embryogenesis and mild hyperoxia increases survival over normoxia.
Hand amputations: epidemiology, management and resurfacing options for soft tissue coverage
Authors: Khurram M. F. , Masoodi Z. , Yaseen M. , Bariar L.M. , Haq A. 
Published: October 2015

Objective: Agricultural hand injuries occur mainly among young adults, many affecting the dominant hand, thereby impeding patients' ability to work or cope with social obligations. This study was carried out with the aim of collecting data on the epidemiology and management of agricultural hand injuries in Indian subjects. Method: The study was conducted in the Department of Plastic and Reconstructive Surgery, JN Medical College, AMU, Aligarh, India, from October 2009 to December 2013. Patients with agricultural hand injuries were included. Data collected included socio-demographic details, mode and type of injury, type of reconstruction, complications, length of hospital stay and assessment of post-reconstruction status. These data were tabulated and analysed. Results: The typical patient was young (mean 33.2 years), of lower socio-economic status and with a total disregard for safety regulations. There is clustering of cases during the wheat harvest season (April–June). Wheat thresher injuries were the most common cause of partial hand amputation (51%), especially during this season. This was followed by fodder cutting (kutti/chara) machine injury, especially in females and children (36%). A simple classification for these injuries has been described and Grade II injury was the commonest. Reverse radial forearm flap was the most suitable regional flap for coverage, whereas thoraco-umbilical flap was the most commonly used distant flap. Patients who had the single-stage procedure had a significantly shorter stay. Conclusion: Agricultural hand injuries are not totally avoidable and their incidence can be reduced by proper education, but the low economic and literacy status of the patients is a big hurdle. The forearm offers many flaps for reconstruction of hand, which can be used in defects on dorsal or palmar aspect of hand and results in early discharge from the hospital and early rehabilitation. In patients with associated injury to the forearm, abdominal flaps can be used for cover.
Experiential luxury shopping at the Louis Vuitton Flagship in Paris: Dramas of identity
Authors: Manlow Veronica 
Published: October 2015

Abstract
Purpose: Outline the dimensions of the luxury shopping experience that distinguish it from hedonic shopping in other contexts. Focus on the meaning the luxury flagship shopping experience has to consumers at the point of purchase.
Design: Ethnographic field study. Observation, interviews and analysis of responses of twenty shoppers at the Louis Vuitton flagship on the Champs-Élysées in Paris.
Findings: Identification of seven general types of experience, the most prevalent having to do with the Paris location and French cultural associations that the brand connotes through the store. Shoppers respond to the symbolic attributes of the brand in defining and enacting a self in the store environment.
Research Limitations: An exploratory study with a small sample and brief interviews. Larger samples at this and other locations will provide us with more data on the key attributes of luxury shopping.
Practical implications: Furthers knowledge on experiential shopping by allowing customers to share their motivations. Of interest to academics and luxury retailers as it illustrates the importance of the store environment and location to customers.
Social implications: Furthers our understanding of the individual in contemporary consumer society within a branded context where the self is dramatically put into play.
Originality/value: Louis Vuitton occupies an important place within the rarified world of luxury brands catering to the aspirations and fantasies of customers. Understanding subjective meanings provided by shoppers as they exist, the store provides a greater depth of understanding of the customer response to luxury brands.
INTEREST-FREE BANKING'S AND CONVENTIONAL BANKING'S ATTITUDES AGAINST FINANCIAL CRISES: THE CASE OF TURKEY
Authors: CANBAZ Mustafa 
Published: October 2015

Following the financial crisis in 2001, Turkish banking sector started a ‘restructuring’ process. This led to recovery of the damage caused by the crisis and, despite the significant decrease in number of the banks, the banking sector gained quite a sound structure. This imrpovement allowed it to remain strong against the global financial crisis that took place after 2007 and caused important progress for many financial indicators, in particular the deposits and loans. Interest- free banking, which has been operating in form of participation bank through the profit and loss sharing system since 2005, become a competitor, in a different aspect, to deposit banks, an important part of the conventional banking. This study compares attitudes of the Participation Banks and the Deposit Banks against their customers before and after the crisis, in light of the financial indicators from the financial statements. The analysis concludes that Particpiation Banksa re significantly different from Deposit Bank in aspect of 'acticity ratios', which are based on the main areas of activity.
BANKACILIKTA MÜŞTERİ İLİŞKİLERİ YÖNETİMİNİN MÜŞTERİ SADAKATİNE ETKİSİ
Authors: GÜMÜŞBUĞA Fikret 
Published: October 2015

Bu çalışmanın ana temasını müşteri ilişkileri yönetimi ve müşteri sadakati kavramları oluşturmaktadır. İlgili yazında önemli bir yer tutan müşteri ilişkileri yönetimi ve müşteri sadakati konularında çok sayıda amprik çalışma yapılmasına rağmen Karabük ili ve Safranbolu ilçesinde faaliyet yürüten banka müşterileri üzerinde yapılan çalışmaların yok denecek kadar az olması çalışmanın hazırlanmasında en büyük etken olmuştur. Çalışma, Karabük ili ve Safranbolu ilçesindeki bankaların müşteri ilişkileri yönetim uygulamalarının müşteri sadakatine olan etkisini tespit etmek amacıyla gerçekleştirilmiştir. Araştırma sonucunda katılımcıların müşteri ilişkileri yönetimi ve müşteri sadakatine ilişkin önermelere ortalamalar açısından katılım düzeyleri düşük çıkmıştır. Ancak müşteri ilişkileri yönetiminin müşteri sadakati üzerinde etkisi olduğu tespit edilmiştir.
Logros y retos de la implementación de derivados financieros estandarizados en Colombia: un análisis comparativo con México, Chile y Perú, 2008-2012
Authors: Carmona Muñoz Diana M. , Higuera Hurtado Danna , Espeleta Bayona Ana 
Published: October 2015

<p>Desde 1999 con la eliminación del sistema de banda cambiaria inicia un desarrollo significativo en el mercado de derivados colombiano (otc)5. Con las recientes crisis financieras internacionales, aumenta la necesidad de estandarizar<br />los productos derivados financieros con el fin de eliminar el riesgo de contraparte presentado en el mercado otc. Este artículo identifica los logros y los retos que presenta el mercado de derivados estandarizado en Colombia desde su creación en 2008 hasta 2012, analizando así años completos; se compara su evolución con la que ha venido presentado México, Chile y Perú en el mismo periodo mediante una matriz de diagnóstico para posteriormente plantear estrategias de desarrollo de mercado, desarrollo de producto, integración horizontal, acceso al mercado y desarrollo de negocio por medio de la adaptación del plan estratégico mexicano al mercado colombiano.<br />Palabras clave: derivados, integración horizontal, mercado estandarizado, riesgo financiero.</p>
La investigación formativa desde la teoría de las representaciones
Authors: Padilla Beltrán José Eduardo , Rincón Caballero Diego Armando , Buitrago Duarte Laura Jimena 
Published: October 2015

<p align="LEFT"> <span style="font-size: medium;">En el marco de la función sustantiva de la Educación Superior, el referente de investigación formativa en la Universidad Militar Nueva Granada constituye un pilar sustancial para el desarrollo del proyecto educativo; por ende, la caracterización de este proceso en sus diferentes instancias, actores y dinámicas propicia una comprensión en torno a la necesidad de procesos formativos sustentados en aspectos representacionales. En ese sentido, este estudio emplea el enfoque cualitativo desde el método de comparación constante como propuesta metodológica para establecer referentes teóricos de la investigación formativa a nivel nacional e institucional, así como aspectos del contenido representacional de jóvenes investigadores y semilleros de investigación interpretados a través de la técnica de asociación libre. Por ello, los resultados giran en torno a una lectura de estas concepciones de la investigación formativa bajo el prisma de la teoría de las representaciones sociales, en tanto permita la comprensión del objeto de estudio desde una perspectiva psicosocial, para luego tener como conclusiones un desarrollo reflexivo acerca de supuestos metodológicos que indaguen por las prácticas, creencias y sistemas representacionales adquiridas sobre la investigación formativa en la Universidad Militar Nueva Granada </span></p>
Analysis of Targeted Bit Speed Technology Performance While Directional Drilling at Urengoyskoe Field (Yamal, Russia)
Authors: Dubrovin Andrey , Abaltusov Nikolay , Rublev Sergey , Kiselev Evgeny , Ovchinnikov Sergey 
Published: October 2015

Abstract
This paper describes the basics of the Targeted Bit Speed (TBS) technology and results of its application during construction of a group of wells at Urengoyskoe field located in Yamal-Nenets Autonomous Area, Russia. It highlights the advantages of TBS technology as compared to drilling with conventional BHA with a hydraulic drilling motor. It also compares various BHA configurations incorporating the TBS system.
The Targeted Bit Speed technology is designed to improve well drilling efficiency. The TBS technology is based on a conventional bent-housing positive displacement motor (PDM) with measurement-while-drilling (MWD) tools. TBS technology delivers the same advantages as rotary-steerable systems enabling full 3D directional control with continuous drillstring rotation. In those cases when the required dogleg severity cannot be achieved with TBS technology, the system's operation can be suspended without retrieving the BHA to the surface with further directional drilling by conventional PDM orientation method.
This paper describes the results of well construction at Urengoyskoe field, where the TBS technology was used by the operator to drill S-shaped wells with a horizontal displacement of over 1,000m.
This paper focuses on directional control improvements, increased rate of penetration (ROP) and rotary drilling share achieved by the new system.
Information provided in the paper applies to the first wells drilled in West Siberia by the TBS method.
Well Completion Selection to Increase the Efficiency of Contact Reserves Development on Example of Van-Yoganskoye Field
Authors: Kuvakina M. , Makarov Y. , Zhuravlev O. 
Published: October 2015

Abstract
The increase of oil production in Russia at present time and in nearest future is connected with commissioning of the largest oil fields with contact deposits. Oil and gas companies are primarily carrying out development of such deposits with the use of a system of horizontal wells. Horizontal wells let increase contact area of a reservoir with a well, and also increase production rates, as well as increase oil recovery factor (ORF) in the whole field. In some cases, the pre-emptive use of horizontal wells is due not only to technological reasons, but also to the economic ones (off-shore projects, remote locations). Despite significant development of drilling technologies (currently it is possible to drill wells with large step out and the sinking of a large reservoir), there is still quite a wide range of issues related to the construction and completion of horizontal wells. These issues include control of sand production, using of casing packers in layouts, as well as the selection and proper use of flow control units for development of fields with contact deposits, and choice of systems for monitoring of work of horizontal wells.
This article describes a procedure and subsequent justification of the choice of a well completion system for increasing efficiency of contact deposit output on the example of Van-Yoganskoe oilfield.