bluuebunny/crossref_metadata_2025_split huggingface dataset:
Community end user perceptions of hessian fabric transfluthrin vapour emanators for protecting against mosquitoes under conditions of routine use in Port-au-Prince, Haiti
Authors: Damus Obrillant , Supreme Chicoye , Lemoine Jean-Frantz , Raccurt Christian , McBeath Justin , Ogoma Sheila B. , Corbel Vincent , Andrinopoulos Katherine , Impoinvil Daniel , Killeen Gerry F. , Czeher Cyrille 
Published: July 2024

Background
A treated fabric device for emanating the volatile pyrethroid transfluthrin was recently developed in Tanzania that protected against night-biting Anopheles and Culex mosquitoes for several months. Here perceptions of community end users provided with such transfluthrin emanators, primarily intended to protect them against day-active Aedes vectors of human arboviruses that often attack people outdoors, were assessed in Port-au-Prince, Haiti.

Methods
Following the distribution of transfluthrin emanators to participating households in poor-to-middle class urban neighbourhoods, questionnaire surveys and in-depth interviews of end-user households were supplemented with conventional and Photovoice-based focus group discussions. Observations were assessed synthetically to evaluate user perceptions of protection and acceptability, and to solicit advice for improving and promoting them in the future.

Results
Many participants viewed emanators positively and several outlined various advantages over current alternatives, although some expressed concerns about smell, health hazards, bulkiness, unattractiveness and future cost. Most participants expressed moderate to high satisfaction with protection against mosquitoes, especially indoors. Protection against other arthropod pests was also commonly reported, although satisfaction levels were highly variable. Diverse use practices were reported, some of which probably targeted nocturnal Culex resting indoors, rather than Aedes attacking them outdoors during daylight hours. Perceived durability of protection varied: While many participants noted some slow loss over months, others noted rapid decline within days. A few participants specifically attributed efficacy loss to outdoor use and exposure to wind or moisture. Many expressed stringent expectations of satisfactory protection levels, with even a single mosquito bite considered unsatisfactory. Some participants considered emanators superior to fans, bedsheets, sprays and coils, but it is concerning that several preferred them to bed nets and consequently stopped using the latter.

Conclusions
The perspectives shared by Haitian end-users are consistent with those from similar studies in Brazil and recent epidemiological evidence from Peru that other transfluthrin emanator products can protect against arbovirus infection. While these encouraging sociological observations contrast starkly with evidence of essentially negligible effects upon Aedes landing rates from parallel entomological assessments across Haiti, Tanzania, Brazil and Peru, no other reason to doubt the generally encouraging views expressed herein by Haitian end users could be identified.
Intrinsic functional connectivity mediates the effect of personality traits on depressive symptoms
Authors: Lee Zheng Long , Siew Savannah Kiah Hui , Yu Junhong 
Published: July 2024

Background
Personality traits have been proposed as risk factors for depressive symptoms. However, the neural mechanism behind these relationships is unclear. This study examined the possible mediating effect of resting-state functional connectivity networks on these relationships.

Methods
Data from 153 healthy Germans were obtained from the MPI-Leipzig Mind-Brain-Body: Neuroanatomy & Connectivity Protocol database. Network-based statistics were used to identify significant functional connectivity networks that were positively and negatively associated with the personality traits of neuroticism, conscientiousness, and extraversion, with and without demographical covariates. Mediation analyses were performed for each personality trait and depressive symptoms with the significant positive and negative network strengths of the respective personality traits as mediators.

Results
Neuroticism, conscientiousness, and extraversion were significantly correlated with depressive symptoms. Network-based statistics identified patterns of functional connectivity that were significantly associated with neuroticism and conscientiousness. After controlling for demographical covariates, significant conscientiousness-associated and extraversion-associated networks emerged. Mediation analysis concluded that only the neuroticism-positive network mediated the effect of neuroticism on depressive symptoms. When age and sex were controlled, the extraversion-positive network completely mediated the effect of extraversion on depressive symptoms.

Conclusions
These findings revealed that patterns of intrinsic functional networks predict personality traits and suggest that the relationship between personality traits and depressive symptoms may in part be due to their common patterns of intrinsic functional networks.
Receipt of Opioid Agonist Treatment in provincial correctional facilities in British Columbia is associated with a reduced hazard of nonfatal overdose in the month following release
Authors: McLeod Katherine E. , Buxton Jane A. , Karim Mohammad Ehsanul , Martin Ruth Elwood , Nosyk Bohdan , Kurz Megan , Scow Marnie , Felicella Guy , Slaunwhite Amanda K. 
Published: July 2024

Background
In many jurisdictions, policies restrict access to Opioid Agonist Treatment (OAT) in correctional facilities. Receipt of OAT during incarceration is associated with reduced risk of fatal overdose after release but little is known about the effect on nonfatal overdose. This study aimed to examine the association between OAT use during incarceration and nonfatal overdose in the 30 days following release.

Methods and findings
Using linked administrative healthcare and corrections data for a random sample of 20% of residents of British Columbia, Canada we examined releases from provincial correctional facilities between January 1, 2015 –December 1, 2018, among adults (aged 18 or older at the time of release) with Opioid Use Disorder. We fit Andersen-Gill models to examine the association between receipt of OAT in custody and the hazard of nonfatal following release. We conducted secondary analyses to examine the association among people continuing treatment initiated prior to their arrest and people who initiated a new episode of OAT in custody separately. We also conducted sex-based subgroup analyses. In this study there were 4,738 releases of 1,535 people with Opioid Use Disorder. In adjusted analysis, receipt of OAT in custody was associated with a reduced hazard of nonfatal overdose (aHR 0.55, 95% CI 0.41, 0.74). This was found for prescriptions continued from community (aHR 0.49, 95%CI 0.36, 0.67) and for episodes of OAT initiated in custody (aHR 0.58, 95%CI 0.41, 0.82). The effect was greater among women than men.

Conclusions
OAT receipt during incarceration is associated with a reduced hazard of nonfatal overdose after release. Policies to expand access to OAT in correctional facilities, including initiating treatment, may help reduce harms related to nonfatal overdose in the weeks following release. Differences in the effect seen among women and men indicate a need for gender-responsive policies and programming.
Estimates of functional muscle strength from a novel progressive lateral step-up test are feasible, reliable, and related to physical activity in children with cerebral palsy
Authors: Batson Trevor , Whitten Sydni V. W. , Singh Harshvardhan , Zhang Chuan , Colquitt Gavin , Modlesky Christopher M. 
Published: July 2024

Objective
To determine if estimates of functional muscle strength from a novel progressive lateral-step-up test (LSUT) are feasible, reliable, and related to physical activity in children with cerebral palsy (CP).

Design
Cross-sectional; test-retest reliability Subjects/Patients: Children with CP and typically developing control children (n = 45/group).

Methods
An LSUT with 10, 15, and 20 cm step heights was completed. It was repeated 4 weeks later in 20 children with CP. A composite score of LSUT was calculated based on the step height and number of repetitions completed. Physical activity was assessed using monitors worn on the ankle and hip.

Results
Only 4 (13%) of the children with CP were unable to complete a lateral step-up repetition without assistance. All children were able to complete at least 1 repetition with assistance, though more than twice as many children with CP required assistance at 15 and 20 cm step heights than at the 10 cm step height (p < 0.01). Children with CP had 59 to 63% lower LSUT performance, 37% lower physical activity assessed at the ankle, and 22% lower physical activity assessed at the hip than controls (all p < 0.01). The intra-class correlation coefficient ranged from 0.91 to 0.96 for LSUT performance at the different step heights and was 0.97 for the composite score. All LSUT performance measures were positively related to ankle physical activity in children with CP (r range = 0.43 to 0.47, all p < 0.01). Only performance at 20 cm and the composite score were positively related to hip physical activity (r = 0.33 and 0.31, respectively, both p < 0.05). The relationship between the LSUT performance and physical activity at both the ankle and hip increased when age and sex were statistically controlled (model r range = 0.55 to 0.60, all p < 0.001).

Conclusion
Estimates of functional muscle strength from a novel progressive LSUT are feasible, reliable, and positively related to physical activity in children with CP.
Microvesicles from quiescent and TGF-β1 stimulated hepatic stellate cells: Divergent impact on hepatic vascular injury
Authors: Xie Jianlong , Ye Zhirong , Xu Xiaobing , Chang Anzhi , Yang Ziyi , Wu Qin , Pan Qunwen , Wang Yan , Chen Yanyu , Ma Xiaotang , Miao Huilai 
Published: July 2024

Background
This study evaluated the effect of microvesicles(MVs) from quiescent and TGF-β1 stimulated hepatic stellate cells (HSC-MVs, TGF-β1HSC-MVs) on H2O2-induced human umbilical vein endothelial cells (HUVECs) injury and CCl4-induced rat hepatic vascular injury.

Methods
HUVECs were exposed to hydrogen peroxide (H2O2) to establish a model for vascular endothelial cell injury. HSC-MVs or TGF-β1HSC-MVs were co-cultured with H2O2-treated HUVECs, respectively. Indicators including cell survival rate, apoptosis rate, oxidative stress, migration, invasion, and angiogenesis were measured. Simultaneously, the expression of proteins such as PI3K, AKT, MEK1+MEK2, ERK1+ERK2, VEGF, eNOS, and CXCR4 was assessed, along with activated caspase-3. SD rats were intraperitoneally injected with CCl4 twice a week for 10 weeks to induce liver injury models. HSC-MVs or TGF-β1HSC-MVs were injected into the tail vein of rats. Liver and hepatic vascular damage were also detected.

Results
In H2O2-treated HUVECs, HSC-MVs increased cell viability, reduced cytotoxicity and apoptosis, improved oxidative stress, migration, and angiogenesis, and upregulated protein expression of PI3K, AKT, MEK1/2, ERK1/2, VEGF, eNOS, and CXCR4. Conversely, TGF-β1HSC-MVs exhibited opposite effects. CCl4- induced rat hepatic injury model, HSC-MVs reduced the release of ALT and AST, hepatic inflammation, fatty deformation, and liver fibrosis. HSC-MVs also downregulated the protein expression of CD31 and CD34. Conversely, TGF-β1HSC-MVs demonstrated opposite effects.

Conclusion
HSC-MVs demonstrated a protective effect on H2O2-treated HUVECs and CCl4-induced rat hepatic injury, while TGF-β1HSC-MVs had an aggravating effect. The effects of MVs involve PI3K/AKT/VEGF, CXCR4, and MEK/ERK/eNOS pathways.
Evaluating the performance of a risk assessment score tool to predict HIV acquisition among pregnant and postpartum women in Kenya
Authors: Chhun Nok , Rothschild Claire W. , Penumetsa Monalisa , Matemo Daniel , Kithao Peninah , Richardson Barbra A. , John-Stewart Grace , Kinuthia John , Drake Alison L. 
Published: July 2024

BackgroundClinical risk score tools require validation in diverse settings and populations before they are widely implemented. We aimed to externally validate an HIV risk assessment tool for predicting HIV acquisition among pregnant and postpartum women. In the context of prevention of mother-to-child transmission programs, risk score tools could be used to prioritize retesting efforts and delivery of pre-exposure prophylaxis (PrEP) to pregnant and postpartum women most at risk for HIV acquisition while minimizing unnecessary perinatal exposure.MethodsData from women enrolled in a cross-sectional study of programmatic HIV retesting and/or receiving maternal and child health care services at five facilities in Western Kenya were used to validate the predictive ability of a simplified risk score previously developed for pregnant/postpartum women. Incident HIV infections were defined as new HIV diagnoses following confirmed negative or unknown status during pregnancy. Predictive performance was assessed using the area under the receiver operating characteristic curve (AUC) and Brier score.ResultsAmong 1266 women with 35 incident HIV infections, we found an AUC for predicting HIV acquisition of 0.60 (95% CI, 0.51, 0.69), with a Brier score of 0.27. A risk score >6 was associated with a 2.9-fold increase in the odds of HIV acquisition (95% CI, 1.48, 5.70; p = 0.002) vs scores ≤6. Women with risk scores >6 were 27% (346/1266) of the population but accounted for 52% of HIV acquisitions. Syphilis, age at sexual debut, and unknown partner HIV status were significantly associated with increased risk of HIV in this cohort.ConclusionThe simplified risk score performed moderately at predicting risk of HIV acquisition in this population of pregnant and postpartum women and may be useful to guide PrEP use or counseling.
Molecular Adsorbent Recirculating System in Acute Liver Failure
Authors: Alsabbagh Alchirazi Khaled , Bhavsar-Burke Indira , Syed Hareem , Alkhayyat Motasem , Bass Stephanie , Kapoor Aanchal , Lindenmeyer Christina C. 
Published: July 2024

ABSTRACT
Acetaminophen (APAP) overdose is the most common cause of acute liver failure (ALF) in the United States. Liver transplantation (LT) is potentially lifesaving for patients with ALF, but its feasibility in clinical practice is limited. Liver assist devices, such as the Molecular Adsorbent Recirculating System (MARS), are used in some centers as a “bridge” to liver transplantation or as a means of liver recovery, but their role in the treatment of ALF is not well-defined. We present the case of a 44-year-old man with APAP-associated ALF who experienced hepatic recovery after treatment with MARS.
Modeling lung endothelial dysfunction in sepsis‐associated ARDS using a microphysiological system
Authors: Liang Nai‐Wen , Wilson Carole , Davis Brooke , Wolf Ian , Qyli Tonela , Moy Joy , Beebe David J. , Schnapp Lynn M. , Kerr Sheena C. , Faust Hilary E. 
Published: July 2024

AbstractEndothelial dysfunction is a critical feature of acute respiratory distress syndrome (ARDS) associated with higher disease severity and worse outcomes. Preclinical in vivo models of sepsis and ARDS have failed to yield useful therapies in humans, perhaps due to interspecies differences in inflammatory responses and heterogeneity of human host responses. Use of microphysiological systems (MPS) to investigate lung endothelial function may shed light on underlying mechanisms and targeted treatments for ARDS. We assessed the response to plasma from critically ill sepsis patients in our lung endothelial MPS through measurement of endothelial permeability, expression of adhesion molecules, and inflammatory cytokine secretion. Sepsis plasma induced areas of endothelial cell (EC) contraction, loss of cellular coverage, and luminal defects. EC barrier function was significantly worse following incubation with sepsis plasma compared to healthy plasma. EC ICAM‐1 expression, IL‐6 and soluble ICAM‐1 secretion increased significantly more after incubation with sepsis plasma compared with healthy plasma. Plasma from sepsis patients who developed ARDS further increased IL‐6 and sICAM‐1 compared to plasma from sepsis patients without ARDS and healthy plasma. Our results demonstrate the proof of concept that lung endothelial MPS can enable interrogation of specific mechanisms of endothelial dysfunction that promote ARDS in sepsis patients.
Investigation of weave influence on flame retardancy of jute fabrics
Authors: Begum Most. Setara , Hummel Michael , Khan Ayub Nabi , Parmar Manjeet Singh , Milašius Rimvydas 
Published: July 2024

Abstract
In the present work, seven different weave-structured jute fabrics were treated using an organophosphorus-based flame-retardant (FR) chemical (ITOFLAM CPN) along with a cross-linking agent (KNITTEX CHN) by the pad–dry–cure method. The flammability properties were determined by vertical and horizontal flammability tests and limiting oxygen index (LOI). The flame-spread and after-glow time in the vertical flammability test were calculated to be zero seconds on the FR-treated fabrics while the untreated fabrics were completely burnt. The burn rate in the horizontal flammability test is also measured at zero seconds on the FR-treated fabrics. The highest LOI (43.33) is found in the Twill-3/1 and 4-ends Irregular Satin fabrics, while other fabrics had similar LOI (40) results after FR treatment. The maximum char length (71 and 74 mm) was determined in the warp and weft directions of the Plain-1/1 fabric, while an average minimum char length was found for Twill-2/2 fabrics. Despite the significant improvement in FR performance, it strongly affects the tensile properties of FR-treated fabrics. A substantial loss of tensile strength loss was measured in all treated fabrics; however, the highest loss (77%) was examined for the Plain-1/1 fabric, and the lowest loss of strength (60%) was in the Basket weave (Matt)-4/4 fabric.
Top Executives’ Overseas Background on Corporate Green Innovation Output: The Mediating Role of Risk Preference
Authors: Cui Luansong , Zhao Jing , Zhao Lijuan , Hu Pan 
Published: July 2024

Abstract
This study employs balanced panel data encompassing Shanghai and Shenzhen A-share listed companies in China spanning the period from 2014 to 2021 as a research dataset, employing a mixed OLS regression model and Bootstrap methods, to investigate the influence mechanism of the overseas background and risk preference tendencies of top executives on the corporate green innovation output. The results show that the top executives’ overseas experience has a substantial influence on corporate green innovation, while top executives’ risk preference level plays a mediating role. In addition, the educational background of top executives is identified as a moderating element in this mechanism. Thus, the conclusions of this article extend prior research by identifying a new connection between top executives’ overseas backgrounds and corporate green innovation and by offering a new perspective to advance and improve the green economy.
Nature of serpentinite interactions with low-concentration sulfuric acid solutions
Authors: Yeskibayeva Chaizada , Auyeshov Abdrazak , Arynov Kazhymuhan , Dikanbayeva Aizhan , Satimbekova Asem 
Published: July 2024

Abstract
The nature of serpentinite interaction with low-concentration sulfuric acid solutions is studied. Using IR-Fourier spectroscopy, X-ray, and serpentinite leaching with sulfuric acid solutions containing 10–60% of stoichiometrically required amount (SRA) of H2SO4 (taken relative to the molar magnesium content in serpentinite), it is shown that the appearance and influence of silica on the course of serpentinite dissolution is detected at concentrations of 30–40% of SRA of H2SO4. On the basis of the obtained results, this article points out the technological, economic, and ecological advantages of use of sulfuric acid solutions of low concentrations in the process of acid processing with the aim of producing magnesium salts.
Re-Staging Existence: Revisiting Kierkegaard’s Theory of Life Stages
Authors: Regier Michael 
Published: July 2024

Abstract
In this paper, we re-evaluate Kierkegaard’s theory of life stages (or spheres) and suggest an alternative interpretation. This alternative approach to the stages will serve as a corrective to problems arising from interpretations promoting an ethical-religious stage, or which elide distinctions between stages entirely. To support this interpretation, we will examine the role polarity plays within the stages, the necessity of respecting the boundaries Kierkegaard draws between stages, and advocate for a greater recognition and appreciation of religiousness A within the broader theory. Our hope is to reveal new avenues for understanding Kierkegaard’s ethics, while also contextualizing the pseudonyms in a way that brings greater clarity and consistency between their respective contributions and his broader oeuvre.
“A Satire on What It Is to Be a Human Being”: A Kierkegaardian Critique of Neoliberal Subjectivity
Authors: Höfer Sophie 
Published: July 2024

Abstract
Neoliberalism has come to be understood not only as an economic system, but as a mode of existence that understands the self as primarily the bearer of human capital. This paper contrasts the neoliberal ideal of selfhood with Kierkegaard’s notion of the self as developed in The Sickness unto Death. Using Kierkegaard’s typology of despair as an analytical framework, I argue that the neoliberal subject displays an impoverished grasp of the various elements that, for Kierkegaard, are constitutive of the self, and shows serious deficiencies in its understanding of what it means to live a meaningful life.
Loyalty voting structures: A better dual class?
Authors: Becht Marco 
Published: July 2024

Abstract
Loyalty voting structures (LVS) are designed to provide registered shareholders with multiple voting rights following a specified holding period. In theory this concept strikes a balance between dual-class structures (DCS), which enshrine founder control, and open structures that allow for control challenges. LVS entail a single class of shares, enabling all shareholders to possess multiple votes without incurring additional costs, while also limiting the privilege through a transfer sunset provision. Notably, LVS also preserve a key control advantage of DCS for founders, as they minimize the likelihood of control challenges through contested board elections. However, in practice LVS distinguish between bearer shares that are fully fungible and registered shares that allow the company to verify the holding period. Institutional shareholders often find it impossible to register their shares, thereby being deprived of multiple voting rights. Consequently, LVS effectively function as a mechanism to enhance control akin to dual-class structures. Transforming loyalty voting structures into a better dual class for institutional shareholders would require some legal and significant procedural modifications.