bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Role of the Gut Microbiota in Sanfilippo Syndrome’s Physiopathology: An Approach in Two Affected Siblings
Authors: Barbero-Herranz Raquel , Garriga-García María , Moreno-Blanco Ana , Palacios Esther , Ruiz-Sala Pedro , Vicente-Santamaría Saioa , Stanescu Sinziana , Belanger-Quintana Amaya , Pintos-Morell Guillem , Arconada Beatriz , del Campo Rosa , Avendaño-Ortiz José 
Published: August 2024

Sanfilippo syndrome, or mucopolysaccharidosis type III (MPS III), is a rare lysosomal disease caused by congenital enzymatic deficiencies in heparan sulfate (HS) degradation, leading to organ dysfunction. The most severe hallmark of MPS III comprises neurological alterations, although gastrointestinal symptoms (GISs) have also been shown to be relevant in many patients. Here, we explored the contribution of the gut microbiota to MPS III GISs. We analyzed the composition and functionality of the gut microbiota in two MPS III siblings with the same mutation (c.544C > T, c.1080delC, in the SGSH gene) and the same diet, but with differences in their GISs, including recurrent diarrhea in one of them. Using 16S sequencing, we observed that the MPS III patients exhibited decreased alpha diversity and a lower abundance of Lachnospiraceae and Bifidobacteriaceae accompanied by a higher abundance of the Ruminococcaceae and Rikenellaceae families than the healthy control subjects. Comparing siblings, we found an increased abundance of Bacteroidaceae and a lower abundance of Ruminococcaceae and Akkermansiaceae in the GIS-free patient. This patient also had a higher relative abundance of Sus genes (SusA, SusB, SusE, and SusG) involved in glycosaminoglycan metabolism. We found higher HS levels in the stool of the two MPS III patients than in healthy volunteers, particularly in the patient with GISs. Functionally, whole fecal metabolites from the patient with GISs induced oxidative stress in vitro in healthy monocytes. Finally, the Bacteroides thetaiotaomicron strain isolated from MPS III stool samples exhibited HS degradation ability. Overall, our results reveal different microbiota compositions and functionalities in MPS III siblings, who exhibited differential gastrointestinal symptomatology. Our study may serve as a gateway to explore the impact of the gut microbiota and its potential to enhance the quality of life in Sanfilippo syndrome patients.
Relationship between the surface free energy of underlayers and the dissolution kinetics of poly(4-hydroxystyrene) partially protected by t-butoxycarbonyl groups in tetramethylammonium hydroxide aqueous developer
Authors: Wang Jiahao , Kozawa Takahiro 
Published: August 2024

Abstract
In the lithography used for the high-volume production of semiconductor devices, the photoresist film becomes thin with the reduction in pattern size to prevent the pattern collapse due to the surface tension of rinsing liquids. The interfacial effect becomes strong with the reduction in photoresist film thickness. In the development process, it is of importance to clarify the relationship between the photoresist and the underlayer for fine patterning. In this study, the dissolution kinetics of poly(4-hydroxystyrene) (PHS) partially protected by t-butoxycarbonyl (t-Boc) groups in tetramethylammonium hydroxide (TMAH) aqueous solution was found to be related to the surface free energy of the underlayer. The attenuation rate of developer viscosity first decreased and then increased with the polar-to-dispersion component ratio. An inflection point with the lowest rate existed. The TMAH concentration affected not only the attenuation rate but also the ratio of polar to dispersion components at the minimum attenuation rate.
Demonstration of β-(Al
x
Ga1−x
)2O3/β-Ga2O3 superlattice growth by mist chemical vapor deposition
Authors: Kaneko Masahiro , Miyake Hiroki , Nishinaka Hiroyuki 
Published: August 2024

Abstract
This study demonstrates the successful growth of a β-(Al
x
Ga1−x
)2O3/β-Ga2O3 superlattice structure with six periods using mist CVD. High-angle annular dark-field scanning transmission electron microscopy (HAADF-STEM) analysis revealed that the superlattice consisted of six periods of β-(Al
x
Ga1−x
)2O3/β-Ga2O3 with an individual layer thickness of 12.9 nm and 9.1 nm, respectively. XRD analysis further confirmed the periodicity of the structure, yielding a period of 22.7 nm, which is in good agreement with the STEM result. Additionally, the Al composition was determined to be x = 0.085 based on XRD peak positions. Both atomic force microscopy and HAADF-STEM observations revealed atomically flat surfaces and sharp interfaces. This achievement highlights the potential of mist CVD for fabricating complex oxide heterostructures, offering a cost-effective and scalable alternative to conventional methods. The findings open new avenues for developing advanced electronic and optoelectronic devices based on wide-bandgap oxides.
AKUPRESUR DENGAN PELVIC ROCKING KOMBINASI AROMATHERAPY LAVENDER MENGURANGI DISMINORE SISWA MTS NU 05 SUNAN KATONG
Authors: Rose Nur Hudhariani  , Gurnita Fauziah  Winda , Maftuchah Maftuchah , Wahyunik Siti Ida 
Published: August 2024

Background: According to WHO 2020 (World Health Organization) , 90% of Indonesian women suffer from dysmenorrhea. Primary dysmenorrhea 72.89%, secondary dysmenorrhea 21.11%, of which 1.31% patients with dysmenorrhea go to midwives.. Results of interviewing 5 people, in which 4 people have dysmenorrhea and only 1 person din’t have dysmenorrhea. Objective: To determine the effectiveness of combining Li4 acupressure with lavender aromatherapy toward the level dysmenorrhea in Mts Nu 05 Sunan Katong Kaliwungu Research Methods: The type of reserch used quasy experimental with the design of two group pre test post test with the intervention of giving Li4 acupressure with lavender aromatherapy and pelvic rocking exercises with lavender aromatherapy. The population is all students of Mts Nu 05 Sunan Katong Kaliwungu and the total sample is 32 students according to inclusion and exclusion criteria. The sampling technique used is accidental sampling. Result: There was a significant effect on Li4 acupressure with lavender aromatherapy and pelvic rocking exercises with lavender aromatherapy on the level of dysmenorrhea pain in Mts Nu 05 Sunan Katong Kaliwungu. The results showed that there was no significant difference between Li4 acupressure with lavender aromatherapy and pelvic rocking exercises with lavender aromatherapy. Conclusion: There is a relationship between Accupresure Li4 with lavnder aromatherapy and Pelvic rocking exercises with lavender aromatherapy at Mts Nu 05 Sunan Katong Kaliwungu.

Keywords: Li4 accupressure, Lavender aromatherapy, Dysmenorrhoea, Pain Levels, Pelvic rocking Exercise,
Pengaruh Model Discovery Learning Berbasis Media Digital Pada Pembelajaran IPS Siswa Kelas VI UPT SPF SD Inpres Maccini Sombala I Kota Makassar
Authors: Jannah Raodatul , Majid Syahriah , Burhan Burhan 
Published: August 2024

Penelitian ini bertujuan untuk mengetahui pengaruh discovery learning berbasis media digital pada pembelajaran IPS siswa kelas VI UPT SPF SD Inpres Maccini Sombala 1 Kota Makassar. Jenis penelitian yang digunakan adalah kuantitatif tipe quasi eksperimental dengan desain penelitian Nonequivalent Control Group Desain. Sampel penelitian adalah siswa kelas VI-A dan VI-B UPT SPF SD Inpres Maccini Sombala 1. Hasil penelitian menunjukkan output uji hipotesis pada sig (2-tailed) sebesar 0,000 < 0.05 maka dapat disimpulkan H0 ditolak dan H1 diterima. Dengan demikian, dapat disimpulkan terdapat pengaruh penerapan model discovery learning berbasis media digital terhadap pembelajaran IPS siswa kelas VI UPT SPD SD Inpres Maccini Sombala 1 Kota Makassar.
This research aims to investigate the influence of digital media-based discovery learning on social studies (IPS) learning among sixth-grade students at UPT SPF SD Inpres Maccini Sombala 1, Makassar City. The research utilized a quantitative quasi-experimental design with a Nonequivalent Control Group Design. The study sample comprised students from classes VI-A and VI-B at UPT SPF SD Inpres Maccini Sombala 1. The hypothesis testing results indicate a significance level of 0.000 < 0.05, leading to the rejection of H0 and acceptance of H1, thereby concluding that the implementation of the digital media-based discovery learning model significantly influences the social studies learning of sixth-grade students at UPT SPF SD Inpres Maccini Sombala 1, Makassar City.
Analisis Komponen Fisik Terhadap Kemampuan Menggiring Bola Permainan Sepak bola SD Inpres Pa’baeng Baeng Kota Makassar
Authors: Irwandi Andi 
Published: August 2024

Jenis penelitian ini adalah deskriptif yang menggunakan rancangan penelitian ”korelasional”.Keseluruhan populasinya adalah murid SD Inpres Pa’Baeng Baeng Kota Makassar. Sampel yang digunakan murid putra sebanyak 30 orang. Teknik penentuan sampel dengan cara undian (simple random sampling). Teknik analisis data yang digunakan adalah analisis deskriptif, analisis koefisien korelasi pearson product moment (r), dan hasil analisis korelasi ganda (R) pada taraf signifikan a = 0,05. (1) Ada hubungan yang signifikan antara koordinasi mata kaki dengan kemampuan menggiring bola pada permainan sepakbola, dengan nilai r sebesar 0,864 (P value < a 0,05);
); (2) Ada hubungan yang signifikan antara kelincahan dengan kemampuan menggiring bola pada permainan sepakbola, dengan nilai r sebesar 0,846 (Pvalue < a 0,05); (3) Ada hubungan yang signifikan antara keseimbangan dengan kemampuan menggiring bola pada permainan sepakbola, dengan nilai r sebesar 0,886 (Pvalue < a 0,05); (4) Ada hubungan yang signifikan antara koordinasi mata kaki, kelincahan dan keseimbangan secara bersama-sama dengan kemampuan menggiring bola pada permainan sepakbola dengan nilai Rhitung sebesar 0,946 (Pvalue < a 0,05); dan nilai Fhitung (F) sebesar 101,387.
This type of research is descriptive research using a "correlational" research design. The entire population is students of SD Inpres Pa'Baeng Baeng, Makassar City. The sample used was 30 male students. The sampling technique was by lottery (simple random sampling). The data analysis technique used was descriptive analysis, Pearson product moment correlation coefficient analysis (r), and the results of multiple correlation analysis (R) at a significance level of a = 0.05. The results of the study showed that; (1) There is a significant relationship between eye-foot coordination and the ability to dribble the ball in soccer games, with an r value of 0.864 (Pvalue < a 0.05); (2) There is a significant relationship between agility and the ability to dribble the ball in soccer games, with an r value of 0.846 (Pvalue < a 0.05); (3) There is a significant relationship between balance and the ability to dribble the ball in soccer games, with an r value of 0.886 (Pvalue < a 0.05); (4) There is a significant relationship between eye-foot coordination, agility and balance together with the ability to dribble the ball in football with an R value of 0.946 (P value < a 0.05); and an F value (F) of 101.387.
Analysis of heart rate variability and anthropometric measurements to compare obesity classes II and III in patients undergoing bariatric surgery
Authors: Ribeiro Gouveia Reis Juliana , De Freitas Gonçalves Danielle , Marques Tonello Maria Georgina , Henrique Magalhães Fernando , Massa Marcelo , Patricio da Silva Alan , Binda Dório , Ariana Peña de Moraes Ibis , Pimentel Renata , Perez Martinez Juliana , Bandeira de Mello Monteiro Carlos 
Published: August 2024

Introduction: obesity is an important public health problem worldwide. It is believed that obese candidates for bariatric surgery present cardiac autonomic dysfunction and that weight reduction achieved through surgical treatment of obesity may promote improvement in autonomic nervous system activity, minimizing cardiovascular risks.
Objective: thus, the objective of this study is to assess the impact of surgical bariatric weight reduction on HRV and on anthropometric measurements (BMI, WHtR, and WC) comparing obesity classes II and III.
Method: the study included 25 obese individuals who underwent a preoperative assessment. Anthropometric measurements and heart rate varability (HRV) were collected preoperatively. The participants were then divided into two groups: obesity class II and obesity class III (class II: BMI from 35 to 39 k/m2, and class III: BMI from > 40 kg/m2). Thirty days after surgery, a postoperative assessment was performed and the data were compared.
Results: our results confirm that both class II and III obesity groups presented altered HRV preoperatively and that the participants in the obesity II group showed a statistically significant increase in the HRV index when compared to the obesity III group, through the mean RR, PNN50, SNS, and stress index.
Conclusion: the findings confirmed the important contribution that bariatric surgery makes to improving metabolic health and lowering important obesity indices. The varying alterations in heart rate variability indicate subtle advantages concerning autonomic function, especially for individuals classified as obese II
Pengelolaan Piutang Dagang Perusahaan
Authors: Javany Vega , Rachman Rachmawaty , Andrianto Toni 
Published: August 2024

Accounts receivable is one of the important assets for a company. Effective management of accounts receivable can contribute to the company's financial success and reduce the risk of losses due to delinquent payments. The management of accounts receivable involves a series of activities that include determining credit policies, monitoring customers, effective collection, handling bad debts, and reporting, as well as the use of appropriate information systems. Companies need to have a clear credit policy to control customer credit risk. In addition, regular customer monitoring can help identify customers who have poor payment potential or are experiencing financial difficulties. PT Elegant Indonesia located at Jalan Lintang raya Kav F7 Sentul Industrial Estate, Bogor is a private company engaged in the automotive sector that sells products such as car seat covers, sofa covers, motorcycle seat covers, velvet carpets, and other car accessories. PT Elegant Indonesia's operational activities are carried out on credit. So that it will cause receivables and management of these receivables. Therefore controlling it is needed (SOP) so that it has a good impact on the company. The purpose of this study is to discuss the understanding, of the importance of managing accounts receivable.

Keywords: Trade Receivables
O protagonismo do agente comunitário de saúde na estratégia de saúde da família
Authors: Souza Bruno Rocha de , Holmes Amanda Lee 
Published: August 2024

Introdução: O programa de Estratégia de Saúde da Família surge na tentativa de reorganizar a saúde básica brasileira, e o papel do agente comunitário de saúde se destaca, sendo considerado crucial nesse processo. Objetivo: Compreender o programa de saúde da família, compreender o processo de trabalho do agente comunitário de saúde na estratégia de saúde da família, além de compreender suas principais responsabilidades e contribuições para o programa, especialmente em relação à assistência aos indivíduos inseridos do programa. Método: Trata-se de uma revisão bibliográfica, exploratório e descritivo ,elaborado pelo método qualitativo, através da seleção de artigos científicos e obras literárias que sejam capazes de responder os questionamentos levantados, sem recorte temporal, no idioma português, pesquisadas de dados da Biblioteca Virtual de Saúde (BVS) , na bases de dados do Google acadêmico, SciELO (Scientific Eletronic Library Online) BDTD (Biblioteca Digital Brasileira de Teses e Dissertações), e periódicos da CAPES. Resultados: Observou-se a importância do agente comunitário de saúde no que compete ao cadastro das famílias no programa, o papel educativo exercido pelo profissional, seu papel dentro da comunidade em que atua, além das dificuldades enfrentadas pelo profissional no seu campo de atuação. Em relação a estratégia de saúde da família, destacou-se o campo de atuação, a sua organização e o foco principal do programa. Conclusões: O ACS é um profissional multifacetado e, requer qualificação adequada e investimento governamental, fortalecendo a ESF e a atenção primária, melhorando a qualidade e a excelência da assistência fornecida aos usuários.
Wind-line Variability and Intrinsic Errors in Observational Mass-loss Rates
Authors: Massa Derck , Prinja Raman K. , Oskinova Lidia M 
Published: August 2024

Abstract
UV wind-line variability in OB stars appears to be universal. In order to quantify this variation and to estimate its effect on a mass-loss rate determined from a single observation, we use the International Ultraviolet Explorer archive to identify nonpeculiar OB stars with well-developed but unsaturated Si iv
λ1400 doublets and at least 10 independent observations. This resulted in 1699 spectra of 25 stars. A simple model was used to translate the observed profile variations into optical depth variations and, hence, variations in measured mass-loss rates. These variations quantify the intrinsic error inherent in any single mass-loss rate derived from a single observation. The derived rates have an overall 1σ variation of about 22%, but this appears to differ with T
eff, being as small at 8% for the hottest stars and up to 45% for the cooler ones. Furthermore, any single determination can differ from the mean by a factor of 2 or more. Our results also imply that mass-loss rates determined from nonsimultaneous observations (such as UV and ground-based data) need not agree. In addition, we use our results to examine the nature of the structures responsible for the variability. Our findings suggest that the optical depth variations result from optically very thick structures occulting more or less of the line of sight to the stellar disk. Further, the smaller optical depth variations in the hottest stars suggest that the structures responsible for the variations are disrupted in their more powerful winds.
SERENADE. II. An ALMA Multiband Dust Continuum Analysis of 28 Galaxies at 5 < z < 8 and the Physical Origin of the Dust Temperature Evolution
Authors: Mitsuhashi Ikki , Harikane Yuichi , Bauer Franz E. , Bakx Tom J. L. C. , Ferrara Andrea , Fujimoto Seiji , Hashimoto Takuya , Inoue Akio K. , Iwasawa Kazushi , Nishimura Yuri , Imanishi Masatoshi , Ono Yoshiaki , Saito Toshiki , Sugahara Yuma , Umehata Hideki , Vallini Livia , Wang Tao , Zavala Jorge A. 
Published: August 2024

Abstract
We present an analysis of the Atacama Large Millimeter-submillimeter Array (ALMA) multiband dust continuum observations for 28 spectroscopically confirmed bright Lyman break galaxies at 5 < z < 8. Our sample consists of 11 galaxies at z ∼ 6 newly observed in our ALMA program, which substantially increases the number of 5 < z < 8 galaxies with both rest-frame 88 and 158 μm continuum observations, allowing us to simultaneously measure the IR luminosity and dust temperature for a statistical sample of z ≳ 5 galaxies for the first time. We derive the relationship between the ultraviolet (UV) slope (β
UV) and infrared excess (IRX) for the z ∼ 6 galaxies, and find a shallower IRX–β
UV relation compared to the previous results at z ∼ 2–4. Based on the IRX–β
UV relation consistent with our results and the β
UV–M
UV relation including fainter galaxies in the literature, we find a limited contribution of the dust-obscured star formation to the total star formation rate density, ∼30% at z ∼ 6. Our measurements of the dust temperature at z ∼ 6–7,

T

dust

=

40.9

−
9.1

+
10.0

K

on average, support a gentle increase of T
dust from z = 0 to z ∼ 6–7. Using an analytic model with parameters consistent with recent James Webb Space Telescope results, we discuss that the observed redshift evolution of the dust temperature can be reproduced by an ∼0.6 dex decrease in the gas depletion timescale and ∼0.4 dex decrease in the metallicity. The variety of T
dust observed at high redshifts can also be naturally explained by scatters around the star formation main sequence and average mass–metallicity relation including an extremely high dust temperature of T
dust > 80 K observed in a galaxy at z = 8.3.
Bayesian Multi-line Intensity Mapping
Authors: Cheng Yun-Ting , Wang Kailai , Wandelt Benjamin D. , Chang Tzu-Ching , Doré Olivier 
Published: August 2024

Abstract
Line intensity mapping (LIM) has emerged as a promising tool for probing the 3D large-scale structure through the aggregate emission of spectral lines. The presence of interloper lines poses a crucial challenge in extracting the signal from the target line in LIM. In this work, we introduce a novel method for LIM analysis that simultaneously extracts line signals from multiple spectral lines, utilizing the covariance of native LIM data elements defined in the spectral–angular space. We leverage correlated information from different lines to perform joint inference on all lines simultaneously, employing a Bayesian analysis framework. We present the formalism, demonstrate our technique with a mock survey setup resembling the SPHEREx deep-field observation, and consider four spectral lines within the SPHEREx spectral coverage in the near-infrared: Hα, [O iii], Hβ, and [O ii]. We demonstrate that our method can extract the power spectrum of all four lines at the ≳10σ level at z < 2. For the brightest line, Hα, the 10σ sensitivity can be achieved out to z ∼ 3. Our technique offers a flexible framework for LIM analysis, enabling simultaneous inference of signals from multiple line emissions while accommodating diverse modeling constraints and parameterizations.
The R-Process Alliance: 2MASS J22132050–5137385, the Star with the Highest-known r-process Enhancement at [Eu/Fe] = +2.45*
Authors: Roederer Ian U. , Beers Timothy C. , Hattori Kohei , Placco Vinicius M. , Hansen Terese T. , Ezzeddine Rana , Frebel Anna , Holmbeck Erika M. , Sakari Charli M. 
Published: August 2024

Abstract
We present stellar parameters and chemical abundances of 47 elements detected in the bright (V = 11.63) very metal-poor ([Fe/H] = −2.20 ± 0.12) star 2MASS J22132050−5137385. We observed this star using the Magellan Inamori Kyocera Echelle spectrograph as part of ongoing work by the R-Process Alliance. The spectrum of 2MASS J22132050−5137385 exhibits unusually strong lines of elements heavier than the iron group, and our analysis reveals that these elements were produced by rapid neutron-capture (r-process) nucleosynthesis. We derive a europium enhancement, [Eu/Fe] = +2.45 ± 0.08, that is higher than any other r-process-enhanced star known at present. This star is only the eighth r-process-enhanced star where both thorium and uranium are detected, and we calculate the age of the r-process material, 13.6 ± 2.6 Gyr, from the radioactive decay of these isotopes. This star contains relatively large enhancements of elements that may be produced as transuranic fission fragments, and we propose a new method using this characteristic to assess the r-process yields and gas dilution in samples of r-process-enhanced stars. Assuming a canonical baryonic minihalo mass of 106
M
⊙ and a 1% metal retention rate, this star formed in a cloud of only ∼600 M
⊙. We conclude that 2MASS J22132050−5137385 exhibits a high level of r-process enhancement because it formed in an environment where the r-process material was less diluted than average.