bluuebunny/crossref_metadata_2025_split huggingface dataset:
Frontal sinus septations predict the presence of supraorbital ethmoid cells
Authors: Comer Brett T. , Kincaid Nathan W. , Smith Nathan J. , Wallace James H. , Kountakis Stilianos E. 
Published: July 2013

Objectives/HypothesisThis study is undertaken to determine if the presence or absence of multiseptated frontal sinuses is associated with the presence or absence of supraorbital ethmoid cells (SOECs).Study DesignAnalysis of prospectively collected data.MethodsSixty consecutive patients with chronic rhinosinusitis were identified from a prospectively collected database at a tertiary‐referral institution as having full‐sinus computed tomography (CT) scans. Preoperative or initial CT scans of the sinuses were reviewed, specifically identifying the presence or absence of supraorbital ethmoid air cells (SOECS) and frontal sinus multiseptated sections on coronal imaging. Statistical analysis was performed using the chi‐squared test to evaluate any association between the two structural entities.ResultsSixty total patients were identified, for a total of 120 sides. Of the 61 sides with frontal septations, 43 (70%) had SOECs present and 18 (30%) did not. Of the 59 sides without frontal sinus septations, 13 (22%) had SOECs present and 46 (78%) did not (chi squared = 28.3; P = 0.0000001). The difference in the presence of supraorbital ethmoid cells between whites and blacks is also statistically significant (chi squared = 4.23; P = 0.040).ConclusionThe presence of frontal sinus septations appears to be significantly associated with and predictive of the presence of supraorbital ethmoid cells. Thus, identifying frontal sinus septations on sinus CT is implicated with more complex anatomy of the frontal recess.Level of EvidenceNA. Laryngoscope, 123:2090–2093, 2013
Glycosylation of Polyphosphazene Nanofibrous Membrane by Click Chemistry for Protein Recognition
Authors: Qian Yue‐Cheng , Ren Ning , Huang Xiao‐Jun , Chen Chen , Yu An‐Guo , Xu Zhi‐Kang 
Published: July 2013

AbstractA novel core/sheath glycosylated polyphosphazene nanofibrous membrane for use in protein recognition is fabricated via coaxial electrospinning process with alkyl polyphosphazene as the sheath and polyacrylonitrile (PAN) as the core, followed by introduction of saccharide residues to the surface of the polyphosphazene nanofibrous membrane using alkyne–azide “click” chemistry. A glucose/protein binding assay effectively demonstrates that this nanofibrous membrane can selectively recognize Con A while showing almost no binding with bovine serum albumin (BSA). Furthermore, the affinity capability of proteins (BSA and Con A) for the glycosylated polyphosphazene surface is investigated quantitatively using a surface plasmon resonance (SPR) technique.magnified image
Screening of CACNA1A and ATP1A2 genes in hemiplegic migraine: clinical, genetic, and functional studies
Authors: Carreño Oriel , Corominas Roser , Serra Selma Angèlica , Sintas Cèlia , Fernández‐Castillo Noèlia , Vila‐Pueyo Marta , Toma Claudio , Gené Gemma G. , Pons Roser , Llaneza Miguel , Sobrido María‐Jesús , Grinberg Daniel , Valverde Miguel Ángel , Fernández‐Fernández José Manuel , Macaya Alfons , Cormand Bru 
Published: July 2013

AbstractHemiplegic migraine (HM) is a rare and severe subtype of autosomal dominant migraine, characterized by a complex aura including some degree of motor weakness. Mutations in four genes (CACNA1A, ATP1A2, SCN1A and PRRT2) have been detected in familial and in sporadic cases. This genetically and clinically heterogeneous disorder is often accompanied by permanent ataxia, epileptic seizures, mental retardation, and chronic progressive cerebellar atrophy. Here we report a mutation screening in the CACNA1A and ATP1A2 genes in 18 patients with HM. Furthermore, intragenic copy number variant (CNV) analysis was performed in CACNA1A using quantitative approaches. We identified four previously described missense CACNA1A mutations (p.Ser218Leu, p.Thr501Met, p.Arg583Gln, and p.Thr666Met) and two missense changes in the ATP1A2 gene, the previously described p.Ala606Thr and the novel variant p.Glu825Lys. No structural variants were found. This genetic screening allowed the identification of more than 30% of the disease alleles, all present in a heterozygous state. Functional consequences of the CACNA1A‐p.Thr501Met mutation, previously described only in association with episodic ataxia, and ATP1A2‐p.Glu825Lys, were investigated by means of electrophysiological studies, cell viability assays or Western blot analysis. Our data suggest that both these variants are disease‐causing.
The future of Facebook fundraising
Authors: Waddingham Jonathan 
Published: July 2013

Facebook is the world's largest social network, and charities are keen to create communities and engage with supporters there; yet few are using any of Facebook's tools to raise money effectively. On the basis of data from Facebook and JustGiving, we will learn how to prompt donors to share their donations, the pound value of a Facebook share, and how to generate the best value from shares. We will also reveal Facebook's best practices for community building, explore the trend for Timeline integration and underline the importance of mobile in the future for Facebook fundraising.Copyright © 2013 John Wiley & Sons, Ltd.
Creation of biofunctionalized plasma polymerized allylamine gradients
Authors: Mangindaan Dave , Kuo Wei‐Hsuan , Kurniawan Hengky , Wang Meng‐Jiy 
Published: July 2013

ABSTRACTA chemical gradient possessing gradual change of amine concentration for every 100 carbon atoms (NHx/100 C) from 4.03 to 1.98 was prepared by plasma polymerization of allylamine on polypropylene films. Electron spectroscopy for chemical analysis and water contact angle (WCA) measurements revealed that the nitrogen incorporation resulted in the amine functionality (CN binding) and, therefore, the formation of the wettability gradient. The gradient showed the WCAs varied from 15° to 90° as the change of amine concentration on the gradient from the nitrogen rich end to the nitrogen deprived end. Furthermore, the interactions between the gradient with mammalian cells revealed that more than twofold cell density was found at the nitrogen rich end when compared with the nitrogen deprived end. Plasma polymerization was demonstrated as an effective method to create controllable chemical gradient and the obtained allylamine gradient was useful for biomaterial applications. © 2013 Wiley Periodicals, Inc. J. Polym. Sci., Part B: Polym. Phys. 2013, 51, 1361–1367
Paradoxien der Geschichtsschreibung zur Baukonstruktion: Eine kurze Untersuchung am Schabolovskaya‐Sendeturm in Moskau
Authors: Hassler Uta , Nozhova Ekaterina 
Published: July 2013

AbstractIm August 2013 ist das 160‐jährige Jubiläum des russischen Ingenieurs V. G. Schuchov (1853 –1939). Der Schabolovskaya‐Sendeturm in Moskau, erbaut 1919 bis 1922, gehört zu seinen bekanntesten und am häufigsten zitierten Arbeiten. Es gibt jedoch sehr wenige Informationen über den Bauprozess und die Konstruktion selber, und der Zugang zum Turm ist beschränkt, was eine traditionelle Bauforschung erschwert. Im Rahmen des D‐A‐CH‐Forschungsprojekts “Konstruktionswissen der frühen Moderne – Schuchovs Strategien des sparsamen Eisenbau“ hat eine Gruppe des IDB der ETH Zürich eine Untersuchung des Turms auf der Basis von Archivmaterial durchgeführt. Innerhalb eines kurzen Zeitraums haben die Autoren einige Artefakte am Turm angebracht, die Verbindungen zwischen einer bestimmten Struktur und der Geschichte der russischen Industrialisierung aufzeigen. Der Aufsatz erläutert die verschiedenen Phasen und Methoden der Bauforschung am Schabolovskaya‐Sendeturm und beschreibt das Themenfeld, das die Erforschung industrieller Strukturen zur Interdisziplinarität hinführt.Paradoxes in construction history: A study of the Schabolovskaya Radio Tower in Moscow, Russia. August of this year marks the 160th anniversary of the birth of Russian engineer V. G. Shukhov (1853–1939). The Schabolovskaya Tower in Moscow, built 1919 to 1922, belongs to his most well‐known and widely cited works. However little is known about its construction and access to the tower is restricted, which creates obstacles for conventional research methods. A group from the IDB at ETH Zurich, acting within the framework of the D‐A‐CH Research Project (Konstruktionswissen der frühen Moderne – Schuchovs Strategien des sparsamen Eisenbaus), has made a new study of the tower, based on archival material and the opportunity of a short investigation of the structure in‐situ. The research group has identified artifacts that help reveal links between this particular structure and the history of Russian industrialization. This article outlines the different stages and methods of construction research employed in the study of the Schabolovskaya Tower and describes the array of themes which continue to push the research of industrial structures towards interdisciplinarity.
Effiziente Dimensionierung von Tragbohlen kombinierter Stahlspundwände
Authors: Kuhlmann Ulrike , Just Adrian , Leitz Bernadette , Grabe Jürgen 
Published: July 2013

AbstractDieser Beitrag befasst sich mit der Optimierung der Stabilitätsnachweise nach DIN EN 1993‐1‐1 für die Bemessung von Tragbohlen kombinierter Stahlspundwände. Neben der Berücksichtigung der Bettung der Tragbohlen im umgebenden Boden ist eine weitere Möglichkeit hierbei die Berücksichtigung des Torsionswiderstandes teilverschweißter Doppeltragbohlen. Da für ausreichend torsionssteife Querschnitte Biegedrillknicken im Nachweis nicht berücksichtigt werden muss, kann der Stabilitätsnachweis durch Ansatz eines wegen der Teilverschweißung erhöhten Torsionswiderstandes ggf. deutlich vereinfacht werden. Zur Bestimmung der tatsächlichen Torsionssteifigkeit wurden sechs Versuche an zwei großformatigen Tragbohlen mit je drei Verschweißungsgraden durchgeführt. Auf der Basis eines numerischen Modells wurden die Versuchsergebnisse nachvollzogen und eine Parameterstudie durchgeführt. An einem konkreten Beispiel wird gezeigt, wie durch Berücksichtigung einer Teilverschweißung eine effiziente Dimensionierung der Tragbohlen kombinierter Stahlspundwände möglich ist.Efficient verification of king piles of combined steel sheet walls. This contribution deals with the optimization of the stability verification according to DIN EN 1993‐1‐1 for the design of combined steel walls built‐up by H‐sections as king‐piles and infill steel sheeting. In addition to the king piles’ embedment in the soil advantage can be taken from the torsional stiffness of partially welded double king piles. Since lateral torsional buckling does not need to be considered for cross sections with a sufficient torsional stiffness, it is possible to simplify the stability verification significantly by considering the partial welding and the resulting increased torsional stiffness. In order to determine the real torsional stiffness, two large‐sized king piles with three degrees of welding were tested. Based on a numerical model the test results were simulated and a parameter study was carried out. For a given example it is shown how the consideration of partial welding allows an efficient design verification of the king piles.
Schrägseilbrücke mit Litzenbündelseilen: Elbebrücke Schönebeck – Ausführungsplanung (Teil 2)
Authors: Anistoroaiei Christian , Heymel Ulrich , Jung Rolf , Sagner Erik 
Published: July 2013

AbstractDie Schrägseilbrücke überspannt den Elbestrom mit einer freien Stützweite von 185 m. Das gut sichtbare Merkmal der Brücke ist der über 73 m hohe A‐Pylon. Die Vorlandbereiche werden linkselbisch mit 16 und rechtselbisch mit 8 weiteren Feldern überquert.Für den insgesamt 1128 m langen Brückenzug wurden die unterschiedlichsten Bauweisen vorteilhaft miteinander kombiniert und ausgeführt.Nachdem im Stahlbau Heft 3/2013 bereits schwerpunktmäßig über die Ausführung des Stahlbaus und der Litzenseile berichtet wurde, sollen in diesem Beitrag die Detailplanung und die statischen Besonderheiten mit ihrem Bezug zur Herstellung im Mittelpunkt stehen.A cable stayed bridge with parallel strand cables: Elbe Bridge Schönebeck (Germany) – Detailed Design (part 2). The cable stayed bridge crosses the River Elbe with a main span of 185 m. The main feature of this bridge is the A‐shaped, about 73 m high pylon. The foreshore areas are crossed by 16 additional spans on the left side and 8 additional spans on the right side of the river. For the bridge with its total length of 1128 m different methods of construction were used.The publication part 1 “Stahlbau Heft 3/2013” contains the construction of the bridge and the stay cables. This part 2 contains the detail design and static aspects in respect of construction.
Bioengineered nanoparticles for siRNA delivery
Authors: Kozielski Kristen L. , Tzeng Stephany Y. , Green Jordan J. 
Published: July 2013

Short interfering RNA (siRNA) has been an important laboratory tool in the last two decades and has allowed researchers to better understand the functions of nonprotein‐coding genes through RNA interference (RNAi). Although RNAi holds great promise for this purpose as well as for treatment of many diseases, efforts at using siRNA have been hampered by the difficulty of safely and effectively introducing it into cells of interest, both in vitro and in vivo. To overcome this challenge, many biomaterials and nanoparticles (NPs) have been developed and optimized for siRNA delivery, often taking cues from the DNA delivery field, although different barriers exist for these two types of molecules. In this review, we discuss general properties of biomaterials and nanoparticles that are necessary for effective nucleic acid delivery. We also discuss specific examples of bioengineered materials, including lipid‐based NPs, polymeric NPs, inorganic NPs, and RNA‐based NPs, which clearly illustrate the problems and successes in siRNA delivery. WIREs Nanomed Nanobiotechnol 2013. doi: 10.1002/wnan.1233This article is categorized under:

Therapeutic Approaches and Drug Discovery > Emerging Technologies
Therapeutic Approaches and Drug Discovery > Nanomedicine for Oncologic Disease
CrVI→CrV Transition in Uranyl Chromium Compounds: Synthesis and High‐temperature X‐ray Diffraction Study of Cs2[(UO2)2(CrO4)3]
Authors: Siidra Oleg I. , Nazarchuk Evgeny V. , Kayukov Roman A. , Bubnova Rimma S. , Krivovichev Sergey V. 
Published: July 2013

AbstractSingle crystals of Cs2[(UO2)2(CrO4)3] (1) were obtained by hydrothermal synthesis. The structure of 1 is based upon 2‐dimensional uranyl chromate layers with the composition [(UO2)2(CrO4)3]2–. The cesium atoms are located in the interlayer under “bulbs” centered at the Cr(2)O4 tetrahedra. The thermal behavior of 1 was studied in air. The diffraction maxima of 1 gradually disappear at approximately 450 °C. At this temperature, peaks of Cs2[(UO2)2(Cr2O8)] (2) appear indicating reduction of Cr6+ to Cr5+. Thermal expansion of 1 and 2 is anisotropic. Thermal expansion of the crystal structure of 1 in the [001] direction is greater than that in the other directions, while thermal expansion in the ab plane is uniform. Thermal expansion of 2 is strongly anisotropic as well with the higher expansion along the direction approximately perpendicular to the layers (along the a axis). The high‐temperature study demonstrates that stable uranyl compounds with Cr5+ may form not only from hydrothermal aqueous solutions, but also as a result of high‐temperature solid‐state reactions.
A discrete‐mechanical approach for computation of three‐dimensional flows
Authors: Abali B.E. , Müller W.H. , Georgievskii D.V. 
Published: July 2013

AbstractDynamical processes modeled with a suitable set of differential equations can be approximately computed with finite element method. However, especially in fluid dynamics, numerical instabilities may occur. In order to circumvent such problems many techniques have been realized over the last four decades. Often the lack of stability is linked to numerical insufficiency, therefore the solution is sought by tuning functional spaces, cf. [5] or by adding stabilizing terms, cf. [18, 19, 41]. Stabilizing terms are needed and helpful, however, they involve coefficients to be found depending on the underlying problem. The purpose of this work is to propose another approach based on first principles producing similar terms so that the numerical approximation converges without using any other parameter but the material constants, which are measurable. The approach eliminates stability problems, first, by setting the primary variables in a fundamental way and, second, by using the balance equations in their global form in a discrete manner instead of a continuous one. Some applications at the end emphasize the usefulness of the lengthy calculations, which we develop in a straightforward and consistent way.
Centre for Addiction and Mental Health Inventory of Gambling Situations: Evaluation of the Factor Structure, Reliability, and External Correlations
Authors: Turner Nigel E. , Littman-Sharp Nina , Toneatto Tony , Liu Eleanor , Ferentzy Peter 
Published: July 2013

Abstract
The development and evaluation of the Centre for Addiction and Mental Health Inventory of Gambling Situations (CAMH-IGS) is described. The CAMH-IGS is based on a cognitive-behavioural approach to addiction that sees excessive gambling as a pattern of behaviour which is learned, and which can be changed. The CAMH-IGS is designed to determine the patterns of behaviour, thoughts or feelings which may trigger problematic gambling, with the goal of developing tailored treatment and relapse-prevention approaches for clients. The information can be used in treatment planning. A sample of 524 gamblers that included 323 problem and probable pathological gamblers was used to evaluate the factor structure, reliability, and external correlations of the CAMH-IGS. The results show that the CAMH-IGS consists of 10 internally reliable subscales that can identify individual differences between clients.
The Educational Gradient in Marriage: A Comparison of 25 European Countries
Authors: Kalmijn Matthijs 
Published: July 2013

AbstractPrevious research has suggested that a new marriage gradient has emerged in the United States, with marriage becoming increasingly the privilege of the better-educated. This article examines whether this is true for Europe and explores differences in the marriage gradient among 25 European countries, using multilevel models. The focus is on the chances of living in a marital (or cohabiting) union during midlife (ages 40–49). Multilevel analyses show that the direction and strength of the gradient depend on the societal context. In countries where gender roles are traditional, better-educated women are less likely to be married than less-educated women; in gender-egalitarian countries, better-educated women are more likely to be married. For men, the educational effect on marriage is absent in traditional countries but becomes positive as gender roles become more equal. Inequality in a society also modifies the gradient: if the degree of economic inequality between educational groups in a society is strong, better-educated men are more likely to be married than less-educated men. In general, the results suggest that there may be an accumulation of social and economic disadvantages for the less well educated in more-developed countries.
Babbage's two lives
Authors: FISCH MENACHEM 
Published: July 2013

AbstractBabbage wrote two relatively detailed, yet significantly incongruous, autobiographical accounts of his pre-Cambridge and Cambridge days. He published one in 1864 and in it advertised the existence of the other, which he carefully retained in manuscript form. The aim of this paper is to chart in some detail for the first time the discrepancies between the two accounts, to compare and assess their relative credibility, and to explain their author's possible reasons for knowingly fabricating the less credible of the two.
THE COURTS AND THE ECHR: A PRINCIPLED APPROACH TO THE STRASBOURG JURISPRUDENCE
Authors: BJORGE EIRIK 
Published: July 2013

AbstractThe way in which the courts in the United Kingdom have interpreted and applied the Ullah principle has created problems in the national application of the European Convention on Human Rights. As is evident particularly in Ambrose, this is partly because Lord Bingham's approach in Ullah has been misunderstood. The article analyses these issues in relation to the notion of binding precedent, finding that judicial authority belongs to principles. The national courts ought not, though that is what the Ullah–Ambrose approach enjoins, to expend their energies seeking to align the case before them with the least dissimilar of the reported cases. Rather they should stand back from the case law of the European Court, and apply the broad principles upon which the jurisprudence is founded.
PROBLEMS IN FAMILY PROPERTY
Authors: Gardner Simon 
Published: July 2013

AbstractThis article addresses and challenges recent comments to the effect that the common law rules about unmarried couples' property rights are uncertain, and (or but) that these rules yield an unfair result in a common scenario. It goes on to consider the Law Commission's proposed scheme aimed at reform of this area, raising the concern that this would violate Article 1 of the First Protocol to the European Convention on Human Rights.
Home fortification with calcium reduces Hb response to iron among anaemic Bangladeshi infants consuming a new multi-micronutrient powder formulation
Authors: Khan Waqas Ullah , Shafique Sohana , Shikder Hasina , Shakur Yaseer Abdul , Sellen Daniel W , Chowdhury Jalal S , Zlotkin Stanley H 
Published: July 2013

AbstractObjectiveTo investigate whether the recommended dietary intake of Ca in anaemic infants compromises the expected Hb response, via home fortification with a new Ca- and Fe-containing Sprinkles™ micronutrient powder (MNP).DesignA double-blind, randomized controlled, 2-month trial was conducted in Bangladesh. Infants were randomized to one of two MNP intervention groups containing Fe and other micronutrients, with or without Ca. Hb, anthropometrics and dietary intake were measured pre- and post-intervention while family demographics were collected at baseline.SettingTwenty-six rural villages in the Kaliganj sub-district of Gazipur, Bangladesh.SubjectsOne hundred infants aged 6–11 months.ResultsA significant increase in Hb (MNP, 13·3 (sd 12·6) g/l v. Ca-MNP, 7·6 (sd 11·6) g/l; P < 0·0001) was noted in infants from both groups. However, infants receiving MNP without Ca had a significantly higher end-point Hb concentration (P = 0·024) and rate of anaemia recovery (P = 0·008). Infants receiving MNP with Ca were more likely to remain anaemic (OR 3·2; 95 % CI 1·4, 7·5). Groups did not differ in dietary intake or demographic and anthropometric indicators.ConclusionsAlthough both groups showed significant improvement in Hb status, the nutrient–nutrient interaction between Fe and Ca may have diminished the Hb response in infants receiving the Ca-containing MNP.