bluuebunny/crossref_metadata_2025_split huggingface dataset:
Photothermal bleaching in time‐lapse photoacoustic microscopy
Authors: Gao Liang , Wang Lidai , Li Chiye , Garcia‐Uribe Alejandro , Wang Lihong V. 
Published: November 2012

AbstractWe studied the phenomenon of photothermal bleaching – a gradual reduction of contrast agent particles during repeated scans in photoacoustic microscopy. The dependence of the photothermal bleaching rate on the excitation pulse energy, pulse duration, and the absorber's size was determined while the laser focal diameter was held constant. Our results showed that, the dependence of the photothermal bleaching rate on the excitation pulse energy differed before and after the absorbers were raised to their melting point by the deposited laser energy. Based on this finding, we suggested an optimal excitation pulse energy, which balances the photothermal bleaching rate and signal amplitude, for time‐lapse imaging applications. (© 2013 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Atomic force microscopy and electrochemical investigation on the corrosion behavior of carbon steel passivated by molybdate and chromate
Authors: Chen Zhenyu , Zhang Xiulan , Huang Ling , Guo Xingpeng 
Published: November 2012

AbstractThe effects of CrO42− and MoO42− ions on the corrosion behavior of carbon steel in 0.5 M NaCl solution have been studied using electrochemical measurements and atomic force microscopy. The results suggest that both ions have good inhibition effects on the general and pitting corrosion of carbon steel. At the same concentration, the inhibition efficiency of CrO42− is higher than that of MoO42−. The passive film formed by CrO42− is also much harder than that formed by MoO42−. The passive films formed by both ions are nonconductive. Microsc. Res. Tech., 2013. © 2012 Wiley Periodicals, Inc.
Improving hospital venous thromboembolism prophylaxis with electronic decision support
Authors: Bhalla Rohit , Berger Matthew A. , Reissman Stan H. , Yongue Brandon G. , Adelman Jason S. , Jacobs Laurie G. , Billett Henny , Sinnett Mark J. , Kalkut Gary 
Published: November 2012

BACKGROUNDVenous thromboembolism (VTE) disease prophylaxis rates among medical inpatients have been noted to be <50%.OBJECTIVEOur objective was to evaluate the effectiveness and safety of a computerized decision support application to improve VTE prophylaxis.DESIGNObservational cohort study.SETTINGAcademic medical center.PATIENTSAdult inpatients on hospital medicine and nonmedicine services.INTERVENTIONA decision support application designed by a quality improvement team was implemented on medicine services in September 2009.MEASUREMENTSEffectiveness and safety parameters were compared on medicine services and nonmedicine (nonimplementation) services for 6‐month periods before and after implementation. Effectiveness was evaluated by retrospective information system queries for rates of any VTE prophylaxis, pharmacologic VTE prophylaxis, and hospital‐acquired VTE incidence. Safety was evaluated by queries for bleeding and thrombocytopenia rates.RESULTSMedicine service overall VTE prophylaxis increased from 61.9% to 82.1% (P < 0.001), and pharmacologic VTE prophylaxis increased from 59.0% to 74.5% (P < 0.001). Smaller but significant increases were observed on nonmedicine services. Hospital‐acquired VTE incidence on medicine services decreased significantly from 0.65% to 0.42% (P = 0.008) and nonsignificantly on nonmedicine services. Bleeding rates increased from 2.9% to 4.0% (P < 0.001) on medicine services and from 7.7% to 8.6% (P = 0.043) on nonmedicine services, with nonsignificant changes in thrombocytopenia rates observed on both services.CONCLUSIONSAn electronic decision support application on inpatient medicine services can significantly improve VTE prophylaxis and hospital‐acquired VTE rates with a reasonable safety profile. Journal of Hospital Medicine 2013;8:115–120. © 2012 Society of Hospital Medicine
Antiglycative effect of fruit and vegetable seed extracts: inhibition of AGE formation and carbonyl‐trapping abilities
Authors: Mesías Marta , Navarro Marta , Gökmen Vural , Morales Francisco J 
Published: November 2012

AbstractBACKGROUNDAdvanced glycation end‐products (AGEs) are the final products derived from the non‐enzymatic glycation process. AGEs are involved in the development of several health complications associated with diabetes and aging. Searching for anti‐ AGE extracts is necessary to mitigate the effects of age‐related pathologies.RESULTSThe antioxidant and antiglycative activities of eight aqueous extracts of fruit and vegetable seeds were evaluated. All seed extracts (3.6 mg mL−1) exhibited anti‐AGE activity in protein–glucose assay, ranging from 20 to 92% inhibition compared with aminoguanidine (4.87 mmol L−1). Green pepper extract exerted the highest anti‐AGE activity. However, peach and pomegranate extracts exhibited the highest anti‐AGE activity in protein–methylglyoxal assay, ranging from 0 to 79% inhibition. Hazelnut, almond and sesame extracts were not effective when methylglyoxal was the promoter. Apricot and peach extracts appeared to inhibit the formation of AGEs through their capacity for direct trapping of 1,2‐dicarbonyls (IC50=0.14 mg mL−1). No relationship between antioxidant and phenolic compound content and antiglycative activity was found. Therefore other hydrophilic constituents in addition to phenolic acids must be involved in the antiglycative activity of the extracts.CONCLUSIONAqueous extracts of fruits and vegetables can be considered in the prevention of glycation‐associated complications of age‐related pathologies. © 2012 Society of Chemical Industry
Analysis of aflatoxins, caffeine, nicotine and heavy metals in Palestinian multifloral honey from different geographic regions
Authors: Swaileh Khalid M , Abdulkhaliq Ahed 
Published: November 2012

AbstractBACKGROUNDHoney is a healthy and nutritious natural product. However, it may contain some natural as well as anthropogenic contaminants that can affect consumer health. The present study was aimed at analysing the content of aflatoxins, nicotine, caffeine and heavy metals in Palestinian multifloral honey.RESULTSThe results indicated the presence of variable amounts of aflatoxins (0.5–22 µg kg−1, mean 12.1 µg kg−1) in all samples analysed, with the highest levels in honey from humid hot semi‐coastal regions. Caffeine was found in 80% of honey samples analysed at levels from 94 to 3583 µg kg−1 (mean 1567 µg kg−1). High levels were recorded in regions where citrus cultivation is common. Nicotine was detected in 67% of honey samples analysed at concentrations between 178 and 9389 µg kg−1 (mean 1567 µg kg−1). High levels were recorded in honey samples from the Northwest Plains where tobacco plantation is practised. Cd and Pb levels in all honey samples were below detection limits, while levels of other toxic metals were generally low.CONCLUSIONSAll honey samples contained aflatoxins, mostly in health‐threatening concentrations. Caffeine and nicotine were recorded in 80 and 67% of honey samples respectively. Heavy metal levels were generally low.
Onset of Posttraumatic Stress Disorder and Major Depression Among Refugees and Voluntary Migrants to the United States
Authors: Rasmussen Andrew , Crager Mia , Baser Ray E. , Chu Tracy , Gany Francesca 
Published: November 2012

Although refugees are generally thought to be at increased risk for posttraumatic stress disorder (PTSD) and major depressive episode (MDE), few studies have compared onset of PTSD and MDE between refugees and voluntary migrants. Given differences in migration histories, onset should differ pre‐ and postmigration. The National Latino and Asian American Survey (NLAAS) is a national representative, complex dataset measuring psychiatric morbidity, mental health service use, and migration history among Latino and Asian immigrants to the United States. Of the 3,260 foreign‐born participants, 660 were refugees (a weighted proportion of 9.52%). Refugees were more likely to report a history of war‐related trauma, but reports of other traumatic events were similar. Premigration onset of PTSD was statistically higher for refugees than voluntary migrants, odds ratio (OR) = 4.86, 95% confidence interval (CI) [2.01, 11.76], where postmigration onset for PTSD was not, OR = 0.61, 95% CI [0.29, 1.28]; a similar pattern was found for MDE, OR = 1.98, 95% CI [1.11, 3.51]; and OR = 1.02, 95% CI [0.65, 1.62], respectively. Although refugees arrive in host countries with more pressing psychiatric needs, onset is comparable over time, suggesting that postmigration refugees and voluntary migrants may be best served by similar programs.
Synthesis of Poly(ϵ‐caprolactone‐co‐methacrylic acid) Copolymer via Phosphazene‐Catalyzed Hybrid Copolymerization
Authors: Xu Jinbao , Yang Hongjun , Zhang Guangzhao 
Published: November 2012

AbstractPoly(ϵ‐caprolactone‐co‐tert‐butyl methacrylate) (CL‐co‐BMA) random copolymer is synthesized via hybrid copolymerization with 1‐tert‐butyl‐4,4,4‐tris(dimethylamino)‐2,2‐bis[tris(dimethylamino)phophoranylidenamino]‐2Λ5,4Λ5‐catenadi(phosphazene) (t‐BuP4) as the catalyst. The copolymer is hydrolyzed into poly(ϵ‐caprolactone‐co‐methacrylic acid) (CL‐co‐MAA), a charged copolymer. Nuclear magnetic resonance, Fourier transform infrared spectroscopy, differential scanning calorimetry, and thermogravimetric analysis measurements indicate that cyclic ester and vinyl monomer form a random copolymer. The degradation of the copolymers has also been studied by use of quartz crystal microbalance with dissipation.
Molecular identification in monophasic and nonmotile variants of Salmonella enterica serovar Typhimurium
Authors: Bugarel M. , Vignaud M.‐L. , Moury F. , Fach P. , Brisabois A. 
Published: November 2012

AbstractVariant strains of Salmonella enterica serovar Typhimurium, lacking one or both flagellar phases have been widely reported. The monophasic S.1,4,[5],12:i:‐ variant has emerged worldwide in the past few years and has become one of the most frequently encountered in many countries. In contrast, monophasic S.1,4,[5],12:‐:1,2 and nonmotile S.1,4,[5],12:‐:‐ strains are rarely described. This study investigated seven molecular markers to identify and delineate monophasic S.1,4,[5],12:i:‐ (n = 90), S.1,4,[5],12:‐:1,2 (n = 25), nonmotile S.1,4,[5],12:‐:‐ (n = 17) strains, and some serovar Typhimurium strains (n = 124) collected through the French Salmonella network between 2001 and 2010. Three markers were commonly detected in serovar Typhimurium and in all variant strains: STM2757, mdh and fliA‐B. Monophasic S.1,4,[5],12:i:‐ were genotypically confirmed by the absence of the fljB, fljA, and hin genes. Nevertheless, 13 (14.5%) of them were positive for these last three genes, revealing monophasic strains named “inconsistent” as previously described. All nonmotile 1,4,[5],12:‐:‐ strains had the fliC, fljA, fljB, and hin genes and the fliC gene was detected in 88% of monophasic S.1,4,[5],12:‐:1,2 strains. The combination of the seven markers detection enables to recognize eight different genotypes within the S.1,4,[5],12:i:‐ collection, among which the Spanish and the U.S. clones previously described could be distinguished and assigned to a genotype. Based on this molecular approach, 71% of the French S.1,4,[5],12:i:‐ collection belonged to the Spanish clone, whereas only 2% were assigned to the U.S. clone. This study highlights the usefulness of these molecular markers and genotypes for identifying lineages, especially among the epidemiologically important monophasic S.1,4,[5],12:i:‐ variant.
Expression patterns and functional evaluation of the UNC5B receptor during the early phase of peripheral nerve regeneration using the mouse median nerve model
Authors: Jaminet Patrick , Köhler David , Rahmanian‐Schwarz Afshin , Lotter Oliver , Mager Alice , Fornaro Michele , Ronchi Giulia , Geuna Stefano , Rosenberger Peter , Schaller Hans‐Eberhard 
Published: November 2012

AbstractIntroduction: In this study, we evaluated the role of the Netrin‐1 receptor UNC5b (Uncoordinated), a neuronal guidance molecule, during peripheral nerve regeneration using the mouse median nerve model. Materials and methods: Using Western blot analysis, we examined the expression changes of UNC5b after transection and microsurgical repair of the mouse median nerve distal to the transection site. We evaluated the histomorphometrical changes and functional recovery of the grasping force after median nerve transection and repair in wild‐type (WT) mice and UNC5b+/− heterozygous mice. Results: In Western blot analysis, we could show a high increase of UNC5b in the nerve segment distal to the injury site at day 14. Histomorphometrical analysis did not show any significant differences between WT animals and heterozygous animals. Using the functional grasping test, we could demonstrate that peripheral nerve regeneration is significantly diminished in heterozygous UNC5b+/− mice. Conclusion: By using the mouse median nerve model in transgenic animals, we demonstrate that the Netrin‐1 receptor UNC5b plays an important role during peripheral nerve regeneration. © 2012 Wiley Periodicals, Inc. Microsurgery, 2013.
Axonal excitability during ischemia in MELAS
Authors: Ng Karl , Kumar Kishore R. , Sue Carolyn , Burke David 
Published: November 2012

IntroductionIn mitochondrial disease, it is likely that energy substrate depletion leads to paralysis of ATPase‐dependent pumps, resulting in membrane depolarization. Axonal depolarization has been demonstrated in a crisis, but not in the resting state. We, therefore, stressed axons using ischemia to see if this would reveal abnormal responses, as occurs in diabetes mellitus.MethodsExcitability of median nerve axons at the wrist was studied in 13 patients with MELAS (6 with glucose intolerance) and 17 control subjects in response to ischemia due to inflation of a cuff around the arm for 10 min.ResultsThere were no significant differences in preischemic measures of axonal excitability or in the intra‐ and postischemic responses.ConclusionsAlthough depolarization has been noted to occur spontaneously during a crisis, we could not demonstrate a defect of axonal ATP‐dependent mechanisms. The mechanisms underlying axonal excitability and neuropathy in diabetes may not apply to MELAS. Muscle Nerve 47: 762–765, 2013
Acute cerebellar infarction in a young patient presenting with diabetic ketoacidosis
Authors: Chaudhary M , Kamalaksha S , Trainer VJ , Obuobie K , Kalhan A 
Published: November 2012

AbstractThe neurological complications of diabetic ketoacidosis (DKA) include cerebral oedema or, rarely, acute cerebrovascular accident (CVA) due to ischaemic brain infarction or haemorrhage. These complications result from complex haemostatic mechanisms involving a state of systemic inflammation, coagulopathy, endothelial dysfunction and loss of blood volume induced by insulin deficiency. The development of cerebral oedema is believed to be under‐reported in adult patients with DKA as compared to children. Only a limited number of case reports exist in the literature regarding the development of CVA as a complication of DKA in adults. A high index of suspicion needs to be maintained for early recognition of neurological complications as associated signs and symptoms may only be subtle and masked by altered sensorium commonly seen in the acute phase of DKA, leading to potentially catastrophic consequences if left untreated.Here we present the case of a 22‐year‐old man with type 1 diabetes who developed cerebellar infarction with associated brainstem herniation as a complication of diabetic ketoacidosis and required urgent neurosurgical intervention. Copyright © 2012 John Wiley & Sons. Practical Diabetes 2012; 29(9): 377–379
RAFT‐mediated synthesis and temperature‐induced responsive properties of poly(2‐(2‐methoxyethoxy)ethyl methacrylate) brushes
Authors: Zengin Adem , Yildirim Ertan , Caykara Tuncer 
Published: November 2012

AbstractWell‐defined, high‐density poly(2‐(2‐methoxyethoxy)ethyl methacrylate) [poly(MEO2MA)] brushes were fabricated through a reliable strategy by the combination of self‐assembly of a monolayer of 3‐aminopropyltrimethoxy silane on silicon surface to immobilize 4‐cyano‐4‐(dodecylsulfanylthiocarbonyl)sulfanyl pentanoic acid chain transfer agent and reversible addition‐fragmentation chain transfer‐mediated polymerization of MEO2MA. The whole fabrication process of the poly(MEO2MA) brushes was followed by water contact angle, grazing angle‐Fourier transform infrared spectroscopy, X‐ray photoelectron spectroscopy, and atomic force microscopy. Characterization of the poly(MEO2MA) brushes, such as molecular weight and thickness determination, were measured by gel permeation chromatography and ellipsometry, and the grafting density was estimated. The temperature‐responsive property of the poly(MEO2MA) brushes was further investigated and the result verified the brush‐to‐mushroom phase transition of the poly(MEO2MA) chains from low to high temperature. © 2012 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem, 2013
Expression of MicroRNAs associated with Gleason grading system in prostate cancer: miR‐182‐5p is a useful marker for high grade prostate cancer
Authors: Tsuchiyama Katsuki , Ito Hideaki , Taga Minekatsu , Naganuma Seiji , Oshinoya Yukinosuke , Nagano Ken‐ichi , Yokoyama Osamu , Itoh Hiroshi 
Published: November 2012

AbstractBACKGROUNDExpression profiles of some microRNAs (miRNAs) were associated with clinicopathological findings in human prostate cancer (PC), but the relative expression of miRNAs among Gleason patterns (GPs) remains unclear. In this study, we investigated the expression of several known microRNAs in each GP of PC.METHODSFormalin‐fixed, paraffin embedded (FFPE) tissue samples were obtained from radical prostatectomy (RP) (patient set 1, n = 43, including (GP 3) n = 22, (GP 4) n = 35, and (GP 5) n = 12) and needle biopsy (patient set 2, n = 10, (GP 4) n = 10). Cancer tissues from each GP and adjacent normal counterparts were separately collected using laser‐captured microdissection (LCM). Real‐time RT‐PCR was performed to determine the relative expression of miRNAs, including miR‐31‐5p, ‐34c‐5p, ‐96‐5p, ‐182‐5p, ‐183‐5p, ‐205‐5p, ‐221‐3p, and ‐222‐3p, which were currently reported to be involved in PC progression.RESULTSIn radical prostatectomy samples, relative expression of miR‐31‐5p, miR‐34c‐5p, and miR‐205‐5p in any GP was significantly decreased compared to normal counterpart. However, no significant difference was detected among GP 3, GP 4, and GP 5. Meanwhile, in the same GP4, expression of miR‐31‐5p miR‐182‐5p, and miR‐205‐5p in cancer tissues obtained from high grade cancer was significantly higher than those obtained from intermediate grade cancer. Validation study using biopsy samples revealed that the relative expression of miR‐182‐5p was statistically higher in high grade cancer even in same GP4.CONCLUSIONSWe confirmed the expression of miR‐182‐5p depended on the cancer grade even in same GP 4. Expression of miRNA associated with Gleason grading system may contribute to more accurate preoperative cancer risk evaluation. Prostate 73: 827–834, 2013. © 2012 Wiley Periodicals, Inc.
TEM observations of dislocations in plastically deformed diamond
Authors: Mussi A. , Eyidi D. , Shiryaev A. , Rabier J. 
Published: November 2012

AbstractType Ib synthetic diamonds from De Beers with a low dislocation density have been deformed under confining pressure under pressure of 5 GPa in a multianvil apparatus between 900 and 1200 °C and in a D‐DIA experimental set up at 1100 °C and strain rate of 7 × 10−5 s−1. TEM observations of diamond deformed at 1100 °C, the lowest deformation temperature where plasticity was unambiguously evidenced are reported in this work. Two types of dislocations have been found to coexist: dissociated and perfect. No large stacking faults resulting from the dissociation splitting blow up under large stress have been observed. Numerous dipoles are found in the microstructure which can be built with perfect or dissociated dislocations. These results are discussed in relation with dislocation core configuration calculations.
Simplistic approach for in situ generation of ZnS quantum dots in polyphenylene sulphide matrix via chalcogen enriched solid–solid reaction technique
Authors: Rumale Narendra , Arbuj Sudhir , Umarji Govind , Shinde Manish , Mulik Uttam , Pokle Anuj , Amalnerkar Dinesh 
Published: November 2012

AbstractHerein, we report in situ synthesis of zinc sulphide (ZnS) quantum dots in polyphenylene sulphide (PPS) matrix employing facile solid–solid reaction. The resultant product reveals formation of cubic nanocrystalline zinc sulphide structure. The HRTEM confirms the formation of zinc sulphide quantum dots (size ∼ 3–4 nm) embedded in the polymer matrix.magnified image Scheme: ZnS QDs by enriched solid–solid reaction in polymer matrix.
Efficient identity‐based strong designated verifier signature schemes
Authors: Duan Meijiao , Xu Jing , Feng Dengguo 
Published: November 2012

ABSTRACTStrong designated verifier signature (SDVS) makes it possible for a signer to convince a designated verifier that he or she has signed a message in such a way that the designated verifier cannot transfer the signature to any third party and no third party can even verify the validity of the signature. Recently, Kang et al. proposed an identity‐based SDVS (IBSDVS) scheme that is claimed to be unforgeable and strong. However, in this paper, we show that their scheme is actually forgeable, delegatable, and not strong. We then propose an improved efficient IBSDVS scheme with short signature size and provide formal security proofs based on the computational Diffie–Hellman assumption in the random oracle model. We also show that the performance of our scheme outperforms all the existing IBSDVS schemes known in the literature. Furthermore, we propose an extension of our scheme achieving the stronger notion of nondelegatability and provide formal security proofs. The extended scheme is also showed to achieve high efficiency and short signature size. Copyright © 2012 John Wiley & Sons, Ltd.
A Luminescent Cage‐Like Complex Constructed by Bidentate Pyridine‐Containing Ligand and Silver Nitrate
Authors: Liu Ying , Yu Ying‐Hui , Liu Yi‐Fu , Hou Guang‐Feng , Wang Xiao‐Dan , Wen Bo , Gao Jin‐Sheng 
Published: November 2012

AbstractThe cage‐like complex, Ag4L4(NO3)4 (1) [L = 1, 4‐bis(pyridine‐2‐ylmethoxy)benzene] was synthesized by the reaction of the flexible bidentate ligand and silver nitrate. It was characterized by elemental analysis, IR spectroscopy, TG, and single‐crystal X‐ray analysis. Complex 1 is reported as the first cage‐like cluster constructed by four nitrate anions bridging two [2+2] macrocycles. A blue luminescent emission and luminescent enhancement effect are observed in complex 1.
Effect of Additives on the Cloud Point of the Octylphenol Ethoxylate (30EO) Nonionic Surfactant
Authors: Rocha Sarah A. N. , Costa Cibele R. , Celino Joil J. , Teixeira Leonardo S. G. 
Published: November 2012

AbstractThe effect of different additives on the cloud point (CP) of an octylphenol ethoxylate (OPEO30) aqueous solution was investigated. The CP of OPEO30 is higher than 100 °C due to its approximately 30 oxyethylene units per molecule, which limits its use in cloud point extraction (CPE) procedures at room temperature. However, the presence of additives can promote a decrease in CP, allowing its use in CPE. Halide presence decreased the CP of OPEO30 in the following order F− > Cl− > Br−. It was also observed that the addition of divalent anions resulted in a more pronounced salting‐out effect than monovalent anions. Blends of OPEO30 and its counterpart with 7.5 units of ethylene oxide (OPEO7.5) were also investigated, and it was verified that the CP of OPEO30 decreased linearly with increasing OPEO7.5 concentration, showing that mixing surfactants is a strategy to be explored. In the presence of small amounts of alcohols that are partially soluble in aqueous solution, such as isobutanol and pentanol, cloudiness was observed at temperatures below the CP of pure OPEO30 solution.