bluuebunny/crossref_metadata_2025_split huggingface dataset:
Interdecadal Variability of the South American Precipitation in the Monsoon Season
Authors: Grimm Alice M. , Saboia João P. J. 
Published: October 2014

AbstractInterdecadal variability modes of monsoon precipitation over South America (SA) are provided by a continental-scale rotated empirical orthogonal function analysis, and their connections to well-known climatic indices and SST anomalies are examined. The analysis, carried out for austral spring and summer, uses a comprehensive set of station data assembled and verified for the period 1950–2000. The presented modes are robust, consistent with previous regional-scale studies and with modes obtained from longer time series over smaller domains. Opposite phases of the main modes show differences around 50% in monthly precipitation. There are significant relationships between the interdecadal variability in spring and summer, indicating local and remote influences. The first modes for both seasons are dipole-like, displaying opposite anomalies in central-east and southeast SA. They tend to reverse polarity from spring to summer. Yet the summer second mode and its related spring fourth mode, which affect the core monsoon region in central Brazil and central-northwestern Argentina, show similar factor loadings, indicating persistence of anomalies from one season to the other, contrary to the first modes. The other presented modes describe the variability in different regions with great monsoon precipitation. Significant connections with different combinations of climatic indices and SST anomalies provide physical basis for the presented modes: three show the strongest connections with SST-based indices, and two have the strongest connections with atmospheric indices. However, the main modes show connections with more than one climatic index and more than one oceanic region, stressing the importance of combined influence.
Are Simulated Megadroughts in the North American Southwest Forced?*
Authors: Coats Sloan , Smerdon Jason E. , Cook Benjamin I. , Seager Richard 
Published: October 2014

Abstract
Multidecadal drought periods in the North American Southwest (25°–42.5°N, 125°–105°W), so-called megadroughts, are a prominent feature of the paleoclimate record over the last millennium (LM). Six forced transient simulations of the LM along with corresponding historical (1850–2005) and 500-yr preindustrial control runs from phase 5 of the Coupled Model Intercomparison Project (CMIP5) are analyzed to determine if atmosphere–ocean general circulation models (AOGCMs) are able to simulate droughts that are similar in persistence and severity to the megadroughts in the proxy-derived North American Drought Atlas. Megadroughts are found in each of the AOGCM simulations of the LM, although there are intermodel differences in the number, persistence, and severity of these features. Despite these differences, a common feature of the simulated megadroughts is that they are not forced by changes in the exogenous forcing conditions. Furthermore, only the Community Climate System Model (CCSM), version 4, simulation contains megadroughts that are consistently forced by cooler conditions in the tropical Pacific Ocean. These La Niña–like mean states are not accompanied by changes to the interannual variability of the El Niño–Southern Oscillation system and result from internal multidecadal variability of the tropical Pacific mean state, of which the CCSM has the largest magnitude of the analyzed simulations. Critically, the CCSM is also found to have a realistic teleconnection between the tropical Pacific and North America that is stationary on multidecadal time scales. Generally, models with some combination of a realistic and stationary teleconnection and large multidecadal variability in the tropical Pacific are found to have the highest incidence of megadroughts driven by the tropical Pacific boundary conditions.
Ensemble Sensitivity Analysis Applied to a Southern Plains Convective Event
Authors: Bednarczyk Christopher N. , Ancell Brian C. 
Published: October 2014

Abstract
Forecast sensitivity of an April 2012 severe convection event in northern Texas is investigated with a high-resolution Weather Research and Forecasting (WRF) Model–based ensemble Kalman filter (EnKF). Through ensemble sensitivity analysis (ESA), which relates a forecast metric to initial and early forecast errors by linear regression, features of the flow are revealed that reflect dynamical relationships with the forecast convection. Results indicate that ESA can be successfully applied to high-resolution forecasts of convection, and the most important features are related to the synoptic-scale flow such as positioning of an upper-level low and lower-level thermodynamic characteristics of air masses. Comparisons of the maximum and minimum convectively active members in the region of interest show that the fields generated by ESA are consistent with the actual evolution of the event: members with more eastward progression of the synoptic-scale system produced a stronger convection forecast. The forecast metric of interest is modified in several ways to further evaluate the strength of the results of the sensitivity analysis. Three different variables acting as convection proxies (reflectivity, vertical velocity, and precipitation) are tested along with changing the location of the forecast metric and its spatial size. These additional tests highlight the same synoptic features of the flow with the only major differences reflecting the importance of magnitude versus position of the convective forecast.
Endoscopic mucosal resection of large rectal adenomas in the era of centralization: Results of a multicenter collaboration
Authors: Barendse RM , Musters GD , Fockens P , Bemelman WA , de Graaf EJ , van den Broek FJ , van der Linde K , Schwartz MP , Houben MH , van Milligen de Wit AW , Witteman BJ , Winograd R , Dekker E ,   TREND
Published: October 2014

Background and objectiveEndoscopic mucosal resection (EMR) of large rectal adenomas is largely being centralized. We assessed the safety and effectiveness of EMR in the rectum in a collaboration of 15 Dutch hospitals.MethodsProspective, observational study of patients with rectal adenomas >3 cm, resected by piecemeal EMR. Endoscopic treatment of adenoma remnants at 3 months was considered part of the intervention strategy. Outcomes included recurrence after 6, 12 and 24 months and morbidity.ResultsSixty‐four patients (50% male, age 69 ± 11, 96% ASA 1/2) presented with 65 adenomas (diameter 46 ± 17 mm, distance ab ano 4.5 cm (IQR 1–8), 6% recurrent lesion). Sixty‐two procedures (97%) were technically successful. Histopathology revealed invasive carcinoma in three patients (5%), who were excluded from effectiveness analyses. At 3 months’ follow‐up, 10 patients showed adenoma remnants. Recurrence was diagnosed in 16 patients during follow‐up (recurrence rate 25%). Fifteen of 64 patients (23%) experienced 17 postprocedural complications.ConclusionIn a multicenter collaboration, EMR was feasible in 97% of patients. Recurrence and postprocedural morbidity rates were 25% and 23%. Our results demonstrate the outcomes of EMR in the absence of tertiary referral centers.
The influence of acute hypoxic exposure on isokinetic muscle force production
Authors: Ivamoto Rafael Kenji , Nakamoto Fernanda Patti , Vancini Rodrigo Luiz , Benedito-Silva Ana Amélia , de Lira Claudio Andre Barbosa , Andrade Marília dos Santos 
Published: October 2014

Abstract
To investigated whether an acute hypoxic stimulus affects muscle strength development assessed by isokinetic dynamometry during maximal knee extension. A total of 15 healthy young men participated in this study (61.9 ± 6.1 kg; 1.72 ± 0.08 m; 20.9 ± 2.6 years). We evaluated knee extension and flexion isokinetic dynamometer performance in normoxic and hypoxic conditions. The analyzed parameters, for concentric contraction, were peak torque and total work measured at 1.05 and 5.23 rad/s; and fatigue index measured at 5.23 rad/s. During isokinetic testing, heart rate and oxygen saturation (SpO2) were monitored. Hypoxic conditions (3,600 m) were simulated, via a mixing chamber, with the dilution being constantly controlled by a PO2 probe. Test reproducibility results (test-retest) for all isokinetic knee parameters were classified as moderate to almost perfect (ICC = 0.694 to 0.932). SpO2 was 88.4 ± 3.4% in the hypoxic condition and 97.1 ± 0.7% in the normoxic condition (p = 0.000, effect size = 0.87). Heart rate was not significantly different between normoxic and hypoxic conditions at the end of the test. There were no significant differences in isokinetic variables evaluated for the extensor and flexor muscles at concentric contraction between the normoxic and hypoxic conditions. Our findings indicate that reduced arterial oxygenation per se has no effect on the muscular isokinetic strength of the knee extensors.
Beyond the evidence: treating pulmonary hypertension in the intensive care unit
Authors: Bauer Seth R , Tonelli Adriano R 
Published: October 2014

AbstractMost patients with pulmonary arterial hypertension succumb to their disease in the ICU; however, limited evidence-based information exists to guide treatment in those that present with advanced right ventricular failure. Critical care physicians should be aware of the complexities of the treatment of patients with pulmonary arterial hypertension and should develop a strategy for their care. Current management is based on the pathophysiology of the disease and involves a multidisciplinary team supported by institutional polices directed at optimizing patient safety.
On the parallel efficiency and scalability of the correntropy coefficient for image analysis
Authors: Rêgo Fontes Aluisio I , Xavier-de-Souza Samuel , Dória Neto Adrião D , de Queiroz Silveira Luiz Felipe 
Published: October 2014

Abstract

Background
Similarity measures have application in many scenarios of digital image processing. The correntropy is a robust and relatively new similarity measure that recently has been employed in various engineering applications. Despite other competitive characteristics, its computational cost is relatively high and may impose hard-to-cope time restrictions for high-dimensional applications, including image analysis and computer vision.

Methods
We propose a parallelization strategy for calculating the correntropy on multi-core architectures that may turn the use of this metric viable in such applications. We provide an analysis of its parallel efficiency and scalability.

Results
The simulation results were obtained on a shared memory system with 24 processing cores for input images of different dimensions. We performed simulations of various scenarios with images of different sizes. The aim was to analyze the parallel and serial fraction of the computation of the correntropy coefficient and the influence of these fractions in its speedup and efficiency.

Conclusions
The results indicate that correntropy has a large potential as a metric for image analysis in the multi-core era due to its high parallel efficiency and scalability.
Alpha-synuclein biology in Lewy body diseases
Authors: Kim Woojin Scott , Kågedal Katarina , Halliday Glenda M 
Published: October 2014

Abstractα-Synuclein is an abundantly expressed neuronal protein that is at the center of focus in understanding a group of neurodegenerative disorders called α-synucleinopathies, which are characterized by the presence of aggregated α-synuclein intracellularly. Primary α-synucleinopathies include Parkinson's disease (PD), dementia with Lewy bodies and multiple system atrophy, with α-synuclein also found secondarily in a number of other diseases, including Alzheimer's disease. Understanding how α-synuclein aggregates form in these different disorders is important for the understanding of its pathogenesis in Lewy body diseases. PD is the most prevalent of the α-synucleinopathies and much of the initial research on α-synuclein Lewy body pathology was based on PD but is also relevant to Lewy bodies in other diseases (dementia with Lewy bodies and Alzheimer's disease). Polymorphism and mutation studies of SNCA, the gene that encodes α-synuclein, provide much evidence for a causal link between α-synuclein and PD. Among the primary α-synucleinopathies, multiple system atrophy is unique in that α-synuclein deposition occurs in oligodendrocytes rather than neurons. It is unclear whether α-synuclein originates from oligodendrocytes or whether it is transmitted somehow from neurons. α-Synuclein exists as a natively unfolded monomer in the cytosol, but in the presence of lipid membranes it is thought to undergo a conformational change to a folded α-helical secondary structure that is prone to forming dimers and oligomers. Posttranslational modification of α-synuclein, such as phosphorylation, ubiquitination and nitration, has been widely implicated in α-synuclein aggregation process and neurotoxicity. Recent studies using animal and cell models, as well as autopsy studies of patients with neuron transplants, provided compelling evidence for prion-like propagation of α-synuclein. This observation has implications for therapeutic strategies, and much recent effort is focused on developing antibodies that target extracellular α-synuclein.
Effect of PEEP on breath sound power spectra in experimental lung injury
Authors: Räsänen Jukka , Nemergut Michael E , Gavriely Noam 
Published: October 2014

Abstract

Background
Acute lung injury (ALI) is known to be associated with the emergence of inspiratory crackles and enhanced transmission of artificial sounds from the airway opening to the chest wall. Recently, we described the effect of ALI on the basic flow-induced breath sounds, separated from the crackles. In this study, we investigated the effects of positive end-expiratory pressure (PEEP) on these noncrackling basic lung sounds augmented during ALI.

Methods
Lung sounds were recorded in six anesthetized, intubated, and mechanically ventilated pigs at three locations bilaterally on the chest wall. Recordings were obtained before and after induction of lung injury with oleic acid and during application of incremental positive end-expiratory pressure.

Results
Oleic acid injections caused severe pulmonary edema predominately in the dependent-lung regions. Inspiratory spectral power of breath sounds increased in all lung regions over a frequency band from 150 to 1,200 Hz, with further power augmentation in dependent-lung areas at higher frequencies. Incremental positive end-expiratory pressure reversed the spectral power augmentation seen with ALI, reducing it to pre-injury levels with PEEP of 10 and 15 cmH2O in all lung regions at all frequencies. The application of positive end-expiratory pressure to normal lungs attenuated spectral power slightly and only over a band from 150 to 1,200 Hz.

Conclusions
We confirm a gravity-related spectral amplitude increase of basic flow-induced breath sounds recorded over lung regions affected by permeability-type pulmonary edema and show that such changes are reversible by alveolar recruitment with PEEP.
Halokinetic deformation adjacent to the deepwater Auger diapir, Garden Banks 470, northern Gulf of Mexico: Testing the applicability of an outcrop-based model using subsurface data
Authors: Hearon Thomas E. , Rowan Mark G. , Giles Katherine A. , Hart William H. 
Published: October 2014

Composite halokinetic sequences (CHS) are unconformity-bounded successions of upturned and thinned strata that form due to drape folding of diapir roofs during passive salt rise. Tabular and tapered CHS have narrow (50–200 m) and broad (300–1000 m) zones of folding, respectively. CHS are originally defined as exposed diapirs bounded by shallow-water strata in La Popa Basin, Mexico. This paper tests the concepts of CHS development at the subsurface, deepwater Auger diapir in the northern Gulf of Mexico. We used 3D wide-azimuth seismic data, well and biostratigraphic data, and structural restorations to interpret and analyzed 11 well-imaged Pleistocene CHS that correlate around the diapir. The lower and uppermost flanks are characterized exclusively by tapered CHS, with wide zones of thinning (240–660 m) and broad taper angles (41°–75°). In between are four discrete CHS with mixed tapered and tabular geometries, with the latter displaying narrow zones of thinning ([Formula: see text]) and negligible taper. Three of the intervals switch geometry around the diapir. The CHS-bounding unconformities typically intersect the salt at cusps and are continuous with bright amplitudes in the minibasins that tie to biostratigraphically defined condensed sections. CHS represent 50–500 kyr time spans and correlate well with fourth-order sea-level cycles. We corroborated many aspects of the published model of CHS development, showed that the formation of CHS due to drape folding was independent of depositional environment and related to fluctuations in sea level and sediment input. The style of CHS is generally determined by the interplay between salt-rise and sediment-accumulation rates, but variable CHS geometries around the diapir within the same interval suggested that the ultimate control is the roof thickness. Our results are critical to understanding and predicting aspects of hydrocarbon traps against salt, including trap geometry, and reservoir distribution.
Geological and geophysical expression of a primary salt weld: An example from the Santos Basin, Brazil
Authors: Jackson Christopher A.-L. , Rodriguez Clara R. , Rotevatn Atle , Bell Rebecca E. 
Published: October 2014

Primary salt welds form at the base of minibasins in response to complete evacuation of autochthonous salt. Analytical and numerical models suggest it is difficult to completely remove salt from a weld by viscous flow alone, which is especially true in multilayered evaporites, within which flow is likely heterogeneous due to lithologically controlled viscosity variations. Welds are important in the hydrocarbon industry because they may provide a hydrodynamic seal and trap hydrocarbons, or may allow transmission of fluids from source to reservoir rocks. Few papers document the subsurface expression of welds, principally because they have not been penetrated by wells or because the associated data are proprietary. We use 3D seismic and borehole data from the Santos Basin, offshore Brazil to characterize the geological and geophysical expression of a primary weld associated with flow of Aptian salt. The seismic data that we evaluated suggested that, locally, presalt and postsalt rocks are in contact at the base of an Upper Cretaceous minibasin, implying that several apparent welds, separated by low-relief salt pillows, are present. However, borehole data indicated that 22 m of anhydrite, carbonate, and sandstone are present in one of the welds, indicating that this and other welds may be incomplete. We find that seismic data may be unable to discriminate between a complete and incomplete weld, and we suggested that, during the subsurface analysis of welds, the term apparent weld is used until borehole data unequivocally proves the absence of salt. Furthermore, we speculate that preferential expulsion of halite and potash salt from the autochthonous layer during viscous flow and welding resulted in the formation of an incomplete weld, which, when compared with the initial autochthonous layer, is volumetrically enriched in nonevaporite lithologies and relatively viscous evaporite lithologies (anhydrite). The composition and stratigraphy of the autochthonous layer may thus dictate weld thickness and seal potential.
Johannes von Epiphaneia – Klassizismus und Literarische Tradition in der Spätantiken Geschichtsschreibung
Authors: Brodka Dariusz 
Published: October 2014

Johannes von Epiphaneia - Classicism and Literary Tradition in Late Antiquity Historiography
The article discusses the historical work of a late 6th century Greek historian John of Epiphania. He wrote a history of Roman-Persian war from its outbreak in 572 to the Khosrau’s restoration to the Persian throne by the emperor Maurice in 591. The work is lost but one fragment survives containing the preface and first five chapters. The analysis of the preserved text shows the impact of the classical authors on John’ approach to history and on his modes of thought.
Author, Narrator, and Literary Character:A Study of Xenophon’s Anabasis
Authors: Hajduk Jacek 
Published: October 2014

Author, Narrator, and Literary Character:A Study of Xenophon’s Anabasis
The article discusses Xenophon’s Anabasis. Its main aim is to present some new research perspectives for Classical Studies. It analyzes such aspects of Xenophon’s opus as author, implied author, narrator, narratee and narrative, as well as literary character and the human context. The article is a sort of introduction to narratological studies, concerning classical narrative texts, which has not so far been thoroughly tested for its inner structure.
Rhetorical theory in the third book of Quintilian’s Institutio oratoria
Authors: Śnieżewski Stanisław 
Published: October 2014

Rhetorical theory in the third book of Quintilian’s Institutio oratoria
Quintilian focuses on presenting the beginnings of rhetorical art, its components, how it is expressed and formed. Rhetoric is an art, though it serves a practical, useful function. Nature gave birth to speech, while observation created the art of speech. Every speech is built out of that which is signified (quae significantur) and that which signifies (quae significant), that is, out of res and verba. The ability to speak is perfected by nature, art and practice, though some authors add imitation as well, whereas Quintilian believes imitation to be a part of ars. The most important question discussed by Quintilian is status, i.e. the basis or foundation, the point of contention in a judiciary dispute. Some call it constitutio, others quaestio, still others quod ex quaestione appareat, while Theodorus of Gadara names it caput, that is kefalaion genikotaton. The Greeks use the term stasis and claim this name was not invented by Hermagoras, but by Naucrates, student of Isocrates, or by Zopyros of Clazomenae. This is the moment when the first clash between the two parties takes place or because it forms the basis of the whole case. However, there does not exist any agreement between the authors on the number and definitions of the term status, nor on the difference between status generales and speciales. In every kind of case there is a cause (causa), the crux of the matter (iudicatio) and the main argument (continens). Insistent begging (rogare), foretelling (iudicare), argumentation (rationem reddere) exist in judiciary, advisory and epideictic speeches. Hermagoras`s opinion that we should consider the subject of the case (quaestio), line of defense (ratio), crux of the matter (iudicatio), the main argument (continens) or, as others call it, the main point of their accusation or defense (firmamentum). There exists a common consensus that quaestio originates from another quaestio and that species can be divided into other species. Quaestio principalis (fundamental) is called zetema. Ratio is a method of defense in a situation when the deed was committed. Quintilian uses a widely known example provided by his predecessors; Orestes killed his mother, he admits it and claims that what he did was right. What counts the most is the authority of the speaker. The orator should possess knowledge and extraordinary virtues of character.