bluuebunny/crossref_metadata_2025_split huggingface dataset:
A cross-sectional study of corneal topography and ocular parameters in patients with myopia
Authors: Ibrahim Faiza , Thulaseedharan Sinumol , Unnikrishnan Laly Thekkemeppilly , Sasidharan Sabna 
Published: July 2024

Myopia is a leading cause of visual impairment. This study aims at determining the changes in corneal asphericity, central corneal radius of curvature, anterior chamber depth, lens thickness, vitreous chamber depth, and axial length with increasing myopia. Spherical equivalent refractive error of each myopic eye was determined and grouped into three, according to increasing powers of myopia. Corneal asphericity (Q value) and central corneal radius of curvature were determined using corneal topography. Anterior chamber depth, lens thickness, vitreous chamber depth, and axial length were determined using Ascan. Changes with increasing myopia was assessed. Among 80 myopic eyes of age group 6 to 40 years, more patients were between 21 to 30 years. 60% of them were males. 60% were low myopes (&#60;-3D), 32% were moderate myopes (-3D to -6D) and 8% were high myopes (&#62;-6D). Mean Q values were -0.49±0.09, -0.39±0.04 and -0.28 ±0.04 for low, moderate and high myopes respectively. Mean values of apical radius of curvature of cornea were 7.66±0.07, 7.53±0.08 and 7.35±0.07 for low, moderate and high myopes respectively. Mean values of anterior chamber depth were 3.19±0.09, 3.32±0.09, 3.88±0.08; vitreous chamber depth were 19.82±0.67, 21.66±0.24, 22.66±0.45 and axial length were 23.01±0.76, 24.98±0.32,26.54±0.51 for low, moderate and high myopes respectively. A statistically significant positive correlation of increasing degrees of myopia was observed with Q value, anterior chamber depth, vitreous chamber depth and axial length; and a statistically significant negative correlation with the apical radius of curvature. In myopic eyes, a statistically significant relation exists between corneal asphericity and spherical equivalent refractive error such that, there is a tendency for the cornea to flatten less rapidly in the periphery with increasing myopia and eyes with higher levels of myopia have steeper central corneal curvature, with deep anterior and vitreous chamber and greater axial length.
Can retinal nerve fiber layer thickness be an indicator of amblyopia – Opening new horizons
Authors: Akhtar Naheed , Aafreen Rumana , Waris Abdul 
Published: July 2024

To study the RNFL thickness in amblyopia at Institute of Ophthalmology, JNMCH, AMU, Aligarh.Prospective cross-sectional study.This study was conducted on 30 amblyopic children of age ranging between 6-16 years at Institute of Ophthalmology, Jawaharlal Nehru Medical College and Hospital, AMU, Aligarh after taking institutional ethical clearance and informed consent from parents of the patients. A brief clinical history was taken and detailed eye examination was done for visual acuity. Evaluation and quantification of strabismus was done. SD- OCT was performed after dilatation of pupil with 1% cyclomid eye drop on all enrolled children for evaluation of RNFL thickness and GCC thickness. RNFL thickness and GCC thickness of amblyopic eyes were compared with the fellow eyes. Data entry and analysis was done using paired t-test and p- values &#60;0.05 was considered statistically significant. JASP application version 0.16.4.0 was used for statistical analysis of data and results.Out of 30 children23 were anisometropic amblyopic and 7 were mixed amblyopic. Average RNFL thickness was more in amblyopic eye as compared to fellow eye. This difference in RNFL thickness between the eyes remained statistically significant in an anisometropic amblyopic eyes (p&#60;0.001) but not in mixed amblyopic eyes (p=0.50). No significant difference was found on comparing GCC thickness between the eyes in both the groups (anisometropic amblyopic and mixed amblyopic) (p=0.88,0.30). Amblyopic eyes have more RNFL thickness than fellow eyes. Therefore, we conclude that amblyopia may involve retinal structure, also exploding the old age myth that only cortical changes are responsible.
Verba volant, scripta manent. Spuścizna dokumentacyjna powstania styczniowego
Authors: Krochmal Anna 
Published: July 2024

Celem niniejszego artykułu jest przypomnienie skomplikowanych losów spuścizny dokumentacyjnej powstania styczniowego oraz ocena jej obecnego potencjału badawczego. Szczególną uwagę poświęcono materiałom źródłowym dotyczącym roli w powstaniu styczniowym Kościołów różnych wyznań, postawy hierarchii kościelnej wobec toczących się wydarzeń oraz udziału duchowieństwa w działaniach powstańczych. Przedmiotem zainteresowania były zarówno materiały archiwalne zgromadzone przez archiwa i instytucje pamięci w Polsce, jak i poza jej obecnymi granicami.
Twórcami spuścizny dokumentacyjnej powstania styczniowego były zarówno organy władzy utworzonego państwa podziemnego i osoby zaangażowane w ruch powstańczy, jak i władze zaborcze. Najważniejsza dla odtworzenia dziejów ruchu narodowego część dokumentacji powstała w toku bieżącej działalności centralnych oraz terenowych władz powstańczych. Główna jej część jest przechowywana w Archiwum Głównym Akt Dawnych w Warszawie i w 2014 r. została wpisana na prestiżową listę krajową w programie UNESCO „Pamięć Świata”. Ważne źródła gromadzą archiwa państwowe w 13 miastach: Kalisz, Płock, Lublin, Łódź, Częstochowa, Kielce, Radom, Piotrków Trybunalski, Warszawa, Siedlce, Zamość, Białystok i Suwałki. Materiały dotyczące reakcji Galicji na wybuch powstania 1863 r. są przechowywane w Archiwum Państwowym w Przemyślu, Archiwum Państwowym w Rzeszowie oraz Archiwum Narodowym w Krakowie. Fragmenty spuścizny dokumentacyjnej powstania zachowały się w archiwach instytucji polonijnych poza krajem oraz w zasobach archiwów państw sąsiadujących obecnie z Polską. Są to materiały przechowywane w archiwach państwowych w Ukrainie (głównie we Lwowie i w Kijowie), Białorusi (archiwa w Mińsku), Litwie (w archiwach i bibliotekach w Wilnie) oraz Rosji (w archiwach w Moskwie i Petersburgu oraz państwowych archiwach obwodowych w Irkucku, Omsku i Tobolsku).
Polska hierarchia katolicka w czasie wielkiej wojny 1914-1918 i wojny z bolszewicką Rosją
Authors: Wysocki Wiesław Jan 
Published: July 2024

Szkic prezentuje postawy hierarchów Kościoła katolickiego w zaborze rosyjskim, pruskim i austriackim na początku wielkiej wojny 1914-1918 i zmiany, jakie nastąpiły pod wpływem okoliczności zewnętrznych oraz przemian świadomościowych w trakcie konfliktu światowego wobec kwestii państwowości polskiej. Zdecydowana większość biskupów opowiedziała się za perspektywą wspierania odradzającego się państwa polskiego i aktywnie w tym procesie uczestniczyła, dając temu wyraz zarówno w sferze życia publicznego, obywatelskiego, jak i kościelnego. Rok 1920, uwieńczony polskimi sukcesami militarnymi, był finałem wojny polsko-bolszewickiej, rozpoczętej w 1919 r., w której ujawniło się na wielu płaszczyznach zaangażowanie zarówno hierarchów katolickich, jak i wspólnot, którym przewodzili. Wiele wskazuje na to, że w żadnym wcześniejszym okresie Kościół nie wykazał się większym zaangażowaniem, jak miało to miejsce w 1920 r.
Changes in Organic Acid Composition, Proton Efflux and Root Length in Rice Genotypes Differing in Grain Zinc Accumulation Efficiency
Authors: Lavanya Yama Santhoshi , Murugesan Dhandapani , Chandrasekhar C.N. , Vijila Kenas 
Published: July 2024

Background: Rice genotypes exhibit notable diversity in grain zinc content, with wild types accumulating higher levels than cultivated varieties, even in zinc-deficient soils. This study focuses on the wild rice genotype Karuppunel (Zn tolerant), along with cultivated varieties CO51 (Zn responsive) and ADT39 (Zn sensitive). The research explores the relationship between the composition of organic acids in root exudates, proton efflux and root length at various growth stages under both +Zn and -Zn conditions. Methods: The experiment was conducted by growing rice genotypes Karuppunel, CO51 and ADT39 under two different zinc applied conditions. Non target based metabolomics was done to study the alterations in organic acid composition in root exudates using LC-MS/MS. Proton efflux was studied by the methodology given by Bashan et al., (1989) and root length was measured from the plant’s base to the tip of the longest root. The data was analyzed by using Metaboanalyst 5.0 software and Origin Pro 2023b, version 10.0.5.157. Result: By non-target metabolomics we identified 14 organic acids were identified in rice root exudates across growth stages in response to zinc. Random Forest analysis’s variable importance plot consistently highlights nicotinic acid in Karuppunel, regardless of zinc conditions. Karuppunel exhibits higher proton efflux of 4.23 and 5.12 ìmole H+ g fresh weight-1 h-1 followed by CO51 i.e., 3.76 and 4.14 ìmole H+ g fresh weight-1 h-1 under +Zn and -Zn respectively, while ADT39 shows lower proton efflux. Despite varying zinc conditions, root length increases across stages, with Karuppunel consistently having the highest length, particularly at grain-filling of 16.65 cm under +Zn and 15.75 cm under -Zn. Understanding these physiological changes may contribute valuable insights for breeders in designing zinc nutrient acquisition-focused breeding programs.
Memaknai Hadis Larangan Makan dan Minum dengan Tangan Kiri di Era Modern (Studi Ma’anil Hadis)
Authors: Muhamad Danil  , Mugiono  , Hedhri Nadhiran  
Published: July 2024

This article is entitled “Interpreting the Hadith of the Prohibition of Eating and Drinking with the Left Hand (Study of Ma’anil Hadith), “. It can be seen that eating and drinking are basic human needs, many Muslims will ignore the sunnah of the prophet Saw, in etiquette when eating and drinking it is recommended to use the right hand. Then to overcome the occurrence of irregularities in carrying out islamic law. Hadith should be understood in a way that remains in accordance with the factors related to the hadith. So that the hadith can be understood textually and contextually. The results showed that the meaning contained in the hadith of the prophet Saw, prohibiting eating and drinking with the left hand with authentic quality, can be used as evidence. The teachings contained in it are a tasyri’iyyah sunnah that must be practiced. The prohibition of eating and drinking using the left hand because it is classified as satnic behavior. Satan and his armies invite people to evil deeds. But in today’s era of increasingly sophisticated develipments, it is very important to educate parents form a young age to make it possible to eat and drink using the right hand.
EFFECT OF VIRGIN COCONUT OIL SUPPLEMENTATION ON AFB SPUTUM CONVERSION RATE, SOD, AND BMI LEVELS IN PULMONARY TUBERCULOSIS PATIENTS
Authors: Muhammad Ajib Nuzula  , Mohamad Isa  , Juhairina  , Haryati  , Isa Ansori  , Erna Kusumawardhani  
Published: July 2024

Highlights
1. VCO can accelerate AFB sputum conversion in tuberculosis infection.
2. VCO can decrease SOD levels as a marker of inflammation.

Abstract
Background: Pulmonary tuberculosis has the potential to raise illness and death rates on a global scale significantly. A low sputum conversion rate for acid-fast bacilli (AFB) and malnutrition are indicators of failure in pulmonary TB treatment. Virgin coconut oil (VCO) contains lauric acid and has antibacterial, antioxidant, and anti-inflammatory effects. Objective: This study aimed to examine the effect of VCO supplementation on sputum AFB conversion rates, superoxide dismutase (SOD) levels, and body mass index (BMI) status of pulmonary TB patients. Material and Methods: This study was an analytic experimental study measuring BMI levels and SOD levels at the Pekauman Community Health Center, Sultan Suriansyah Hospital, and Ulin Hospital, Banjarmasin, Indonesia, between July and September 2023. This study, 40 samples were separated into two groups: the treatment group, which received first-line antithyroid drugs (ATD) with VCO, and the control group, which received first-line ATD and a placebo. Results: Based on the proportion, there was an improvement in the acceleration of BTA sputum conversion, and from the mean BMI and the median value of both groups, there was a decrease in SOD levels after VCO administration. No statistically significant association was found between VCO administration and accelerating the AFB sputum conversion and BMI at the end of the fourth and eighth weeks (p>0.05). Additionally, there was no relationship considered between VCO administration and reducing SOD levels before and after treatment (p>0.05). Conclusion: VCO administration had no relationship with the level of AFB sputum conversion, reduction in SOD levels, and BMI status in pulmonary TB patients.
FEATURES OF THE CLINICAL MANIFESTATIONS OF AUTOIMMUNE OPTIC NEUROPATHY IN MULTIPLE SCLEROSIS ON CORTICOSTEROID THERAPY
Authors: Dalia Sharliz Raihana  , Lukisiari Agustini  , Deasy Fetarayani  
Published: July 2024

Highlights

Intravenous corticosteroid treatment followed by oral clinical treatment can reduce the incidence of post-treatment optic neuritis recurrenc
Visual acquisition increases at one-month post-treatment.

Abstract
Background: The clinical picture of autoimmune optic neuropathy, known as neuritis, is strongly influenced by the unique structure of the human anterior visual pathway. The central nervous system autoimmune is related to multiple sclerosis (MS). Optic neuropathy is an injury that frequently results in acute inflammatory damage. Objective: This study aimed to determine the clinical manifestations of autoimmune optic neuropathy in multiple sclerosis and identify diseases with appropriate corticosteroid therapy using systematic review methods. Material and Method: This study used a systematic review method to analyze topic-related kinds of literature on Scopus, PubMed, and Google Scholar databases. The literature screening process was carried out based on the PRISMA 2020 guidelines. Result: Regarding the post-treatment recurrence rate of optic neuritis, the use of intravenous corticosteroids alone and intravenous corticosteroid followed by oral administration may clinically reduce the incidence of recurrence in the patients compared those receiving placebo and oral administration. This suggests that intravenous corticosteroid followed by oral corticosteroid treatment is effective in helping to reduce the incidence of recurring optic neuritis. Conclusion: Intravenous corticosteroid treatment followed by oral administration may clinically reduce the incidence of post-treatment recurrence of optic neuritis in multiple sclerosis (MS) patients.
DEPLETION OF LYSYL OXIDASE-LIKE 4 (LOXL4) ATTENUATES COLONY FORMATION IN VITRO AND COLLAGEN DEPOSITION IN VIVO BREAST CANCER MODEL
Authors: Ni Luh Gede Yoni Komalasari  , I Gde Haryo Ganesha  , I Gusti Nyoman Sri Wiryawan  , Nahoko Tomonobu  , Masakiyo Sakaguchi  
Published: July 2024

Highlights

Revealing LOX family members' mechanisms in promoting invasive breast cancer progression is essential for targeting specific molecules in invasive breast cancer.
Depletion of LOXL4 in invasive breast cancer shows attenuation of cell invasiveness in vitro and collagen deposition in tumor models in vivo.

Abstract
Background: Lysyl oxidase (LOX) family proteins have recently become a topic in cancer progression. Our recent study found a high expression of LOX-like 4 (LOXL4) in MDA-MB-231 cells. Objective: To reveal the impact of depleted LOXL4 in both in vitro and in vivo breast cancer models from a histological perspective. Material and Method: Endogenous LOXL4 was depleted using the CRISPR/Cas9 on MDA-MB-231 parental cells. Based on the LOXL4 protein expression, the clone was determined for the next experiment, thus generating MDA-MB-231 LOXL4 KO. Cell assay was conducted using colony formation assay (n=3) followed by crystal violet staining. The indicated cells were inoculated orthotopically to female BALB/c nude mice (n=5). At the end of the experiment, tumors were isolated, fixed, and prepared for Masson Trichrome staining. Result: CRISPR/Cas9 completely depleted LOXL4 expression on clone number #2-22. Depletion of LOXL4 reduced the colony size formed by MDA-MB-231 cells. MDA-MB-231 LOXL4 KO #2-22 derived tumors showed depressed tumor volume compared to the parental group. Reduced collagen was also observed from the Masson Trichrome staining (p<0.001). Conclusion: Depletion of LOXL4 downregulates the growth of MDA-MB-231 cells in vitro and collagen deposition in vivo.
DEMOGRAPHIC CHARACTERISTICS AND ABO BLOOD GROUP GENOTYPES DISTRIBUTION AMONG SICKLE CELL ANEMIA PATIENTS IN BIRNIN KEBBI, NORTHWESTERN NIGERIA
Authors: Tajudeen Olanrewaju Yahaya  , Asiya Koko Attahiru  , Abdulgafar Bala Ibrahim  , Mutiyat Kehinde Adewale  , Adamu Zainab Fari  , Abdullahi Saadatu  
Published: July 2024

Highlights

Sickle cell anemia affects both males and females in Birnin Kebbi and is predominant among children between 1 to 10 years of age.
It is also more prevalent but less severe among individuals with O- and A+ ABO blood groups in the city.

Abstract
Background: Demographic information and ABO blood group genotypes have been shown by studies to be useful tools in the management of sickle cell anemia. Regrettably, there is a dearth of literature on this information in Birnin Kebbi, northwestern Nigeria. Objective: This study determined demographic characteristics, ABO blood group genotypes, and sickle cell genotypes of sickle cell anemia patients in Birnin Kebbi. Material and Method: A structured checklist was used to collect data from the medical records of 99 patients who attended the Federal Medical Center in the city between November 2022 to November 2023. Result: The results revealed that most of the patients fell within the 1 to 10 years age group, comprising 44 individuals (44.4%), and the 11 to 20 years age group, comprising 33 individuals (33.3%). Of the patients, 48 (48.5%) were males, while 51 (51.5%) were females. Patients with ABO blood genotype O- (33.3%) and A+ (18.0%) were the most prevalent and least severely affected, while blood groups O+ (3%) and AB- (6%) were the least prevalent and most severely affected. Two variants of sickle cells (HbSS and HbSC) were identified, with HbSS (92.9%) being the most prevalent. Conclusion: Based on these findings, efforts should be made to ensure an ample blood supply with groups O-, A, and AB+ in blood banks. Moreover, studies have shown ABO blood groups to influence responses to diets, so precision medicine tailored to individual patients' blood groups is recommended. Individuals with O+ and AB- -blood groups should be given special attention, as they exhibit the severe form of the disease.
DOES THE NIAS TRIBE'S HEAD CIRCUMFERENCE CORRELATE WITH BODY HEIGHT?
Authors: Windy Juwita Lumbanraja  , Saharnauli Janna Verawaty Simorangkir  , Joseph Partogi Sibarani  
Published: July 2024

Highlights

A significant correlation was found between head circumference and height among Nias tribe students.
This study was conducted to obtain formulations on weight determination based on headbands in the Nias tribe.

Abstract
Background: Anthropometric measures are one of the protocols frequently employed to identify deceased bodies. Height, age, and gender are a few anthropometric traits that might be utilized to identify the victim from the corpse. If body components are absent, head circumference can be used to determine body height. Objective: The goal of the study was to ascertain whether there is a correlation between head circumference and body height by gender and to create formulas for estimating weight based on head circumference in the Nias tribe at the University of HKBP Nommensen Medan, Indonesia. Material and Method: The study was conducted from September to October 2023 at the University of HKBP Nommensen using an observational cross-sectional design. Of the 100 students who met the inclusion criteria, 50 were men, and the remaining 50 were women. The study's dependent variable was micro-toise-measured height. The head circumference, expressed in meters of tape, served as the study variable. Result: Statistical analysis of the study results from a significant correlation between the head circumference and the height (r = 0.655, p<0.01). The linear regression equation obtained was y = 3200 x - 2.672 in men and y = 10970 + 2.728 times in women, where y was height and x was head circumference. Conclusion: A substantial height-head circumference association was found among the Nias tribe at the University of HKBP Nommensen Medan, Indonesia. The identification method of the forensic field may benefit from this research.
ANALISIS KLASIFIKASI SUB DAS MANDIANGIN BESERTA UPAYA PENGELOLAANNYA DALAM KAWASAN HUTAN DENGAN TUJUAN KHUSUS UNIVERSITAS LAMBUNG MANGKURAT
Authors: Suryanto Edi , Suyanto Suyanto , Kadir Syarifuddin 
Published: July 2024

Salah satu DAS Prioritas untuk dilakukan perbaikan kinerja manajemennya yaitu DAS Barito. Pada kawasan SUB DAS Mandiangin sendiri memiliki banyak aktivitas penggunaaan lahan didalamnya. Tujuan dari penelitian ini yaitu menganalisis komponen daya dukung, klasifikasi, dan menentukan upaya pengelolaan sumber daya alam dan lingkungan yang sesuai dengan klasifikasi DAS dalam KHDTK ULM. Penelitian ini menggunakan deskriptif kuantitatif, dengan pembobotan kelima komponen utama dalam klasifikasi DAS. Hasil menunjukkan tingkat pemulihan tanah (persentase tanah kritis tinggi, tutupan vegetasi rendah, indeks erosi tinggi), tata air (rendahnya koefisien rejim aliran, tingginya koefisien aliran tahunan, sedimen sedang, banjir rendah, indeks penggunaan air tinggi), sosial ekonomi (tingginya tekanan penduduk, rendahnya ketersediaan penduduk, penegakan sedang), investasi bangunan air (peringkat kota) rendah, nilai konstruksi air pemulihan rendah), pemanfaatan ruang regional (kawasan lindung rendah, kawasan budidaya tinggi). Nilai pembobotan komponen daya dukung SUB DAS Mandiangin adalah 116,00, termasuk dalam klasifikasi DAS yang memerlukan pemulihan daya dukung dan daya tampung. Upaya pegelolaan sumber daya alam dan lingkungan untuk pemulihan daya dukung dapat dilakukan berdasarkan skala prioritas dengan merujuk hasil beberapa komponen dengan kriteria pemulihan sangat tinggi, tinggi dan sedang. Untuk kriteria pemulihan rendah dan sangat rendah dapat dilakukan kegiatan monitoring, pencegahan, pengamanan, pengendalian dan perlindungan agar kualitas tidak menurun.