bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association of lifestyle with sleep health in general population in China: a cross-sectional study
Authors: Zheng Yong-Bo , Huang Yue-Tong , Gong Yi-Miao , Li Ming-Zhe , Zeng Na , Wu Shui-Lin , Zhang Zhi-Bo , Tian Shan-Shan , Yuan Kai , Liu Xiao-Xing , Vitiello Michael V. , Wang Yu-Mei , Wang Yong-Xiang , Zhang Xiu-Jun , Shi Jie , Shi Le , Yan Wei , Lu Lin , Bao Yan-Ping 
Published: August 2024

AbstractThe concept of a healthy lifestyle is receiving increasing attention. This study sought to identify an optimal healthy lifestyle profile associated with sleep health in general population of China. An online cross-sectional survey was conducted from June to July 2022. Six healthy lifestyle factors were assessed: healthy diet, regular physical exercise, never smoking, never drinking alcohol, low sedentary behavior, and normal weight. Participants were categorized into the healthy lifestyle (5-6 factors), average (3-4 factors), and unhealthy lifestyle groups (0-2 factors). The study’s primary outcome was sleep health, which included sleep quality, duration, pattern, and the presence of any sleep disorder or disturbance, including insomnia, excessive daytime sleepiness, obstructive apnea syndrome, and narcolepsy. Multivariable logistic regression analysis was applied to explore lifestyles associated with the selected sleep health outcomes. 41,061 individuals were included, forming 18.8% healthy, 63.8% average, and 17.4% unhealthy lifestyle groups. After adjusting for covariates, participants with healthy lifestyle were associated with a higher likelihood of good sleep quality (OR = 1.56, 95% CI = 1.46–1.68), normal sleep duration (OR = 1.60, 95% CI = 1.49–1.72), healthy sleep pattern (OR = 2.15, 95% CI = 2.00–2.31), and lower risks of insomnia (OR = 0.66, 95% CI = 0.61–0.71), excessive daytime sleepiness (OR = 0.66, 95% CI = 0.60–0.73), and obstructive apnea syndrome (OR = 0.40, 95% CI = 0.37–0.43), but not narcolepsy (OR = 0.92, 95% CI = 0.83–1.03), compared to those with unhealthy lifestyle. This large cross-sectional study is the first to our knowledge to quantify the associations of a healthy lifestyle with specific aspects of sleep health. The findings offer support for efforts to improve sleep health by modulating lifestyle.
Gene body methylation evolves during the sustained loss of parental care in the burying beetle
Authors: Sarkies Peter , Westoby Jennifer , Kilner Rebecca Mary , Mashoodh Rahia 
Published: August 2024

AbstractEpigenetic modifications, such as 5-methylcytosine (5mC), can sometimes be transmitted between generations, provoking speculation that epigenetic changes could play a role in adaptation and evolution. Here, we use experimental evolution to investigate how 5mC levels evolve in populations of biparental insect (Nicrophorus vespilloides) derived from a wild source population and maintained independently under different regimes of parental care in the lab. We show that 5mC levels in the transcribed regions of genes (gene bodies) diverge between populations that have been exposed to different levels of care for 30 generations. These changes in 5mC do not reflect changes in the levels of gene expression. However, the accumulation of 5mC within genes between populations is associated with reduced variability in gene expression within populations. Our results suggest that evolved change in 5mC could contribute to phenotypic evolution by influencing variability in gene expression in invertebrates.
Phylogenomic analyses of all species of swordtail fishes (genus Xiphophorus) show that hybridization preceded speciation
Authors: Du Kang , Ricci Juliana Morena Bonita , Lu Yuan , Garcia-Olazabal Mateo , Walter Ronald B. , Warren Wesley C. , Dodge Tristram O. , Schumer Molly , Park Hyun , Meyer Axel , Schartl Manfred 
Published: August 2024

AbstractHybridization has been recognized to play important roles in evolution, however studies of the genetic consequence are still lagging behind in vertebrates due to the lack of appropriate experimental systems. Fish of the genus Xiphophorus are proposed to have evolved with multiple ancient and ongoing hybridization events. They have served as an informative research model in evolutionary biology and in biomedical research on human disease for more than a century. Here, we provide the complete genomic resource including annotations for all described 26 Xiphophorus species and three undescribed taxa and resolve all uncertain phylogenetic relationships. We investigate the molecular evolution of genes related to cancers such as melanoma and for the genetic control of puberty timing, focusing on genes that are predicted to be involved in pre-and postzygotic isolation and thus affect hybridization. We discovered dramatic size-variation of some gene families. These persisted despite reticulate evolution, rapid speciation and short divergence time. Finally, we clarify the hybridization history in the entire genus settling disputed hybridization history of two Southern swordtails. Our comparative genomic analyses revealed hybridization ancestries that are manifested in the mosaic fused genomes and show that hybridization often preceded speciation.
Fasting induces metabolic switches and spatial redistributions of lipid processing and neuronal interactions in tanycytes
Authors: Brunner Maxime , Lopez-Rodriguez David , Estrada-Meza Judith , Dali Rafik , Rohrbach Antoine , Deglise Tamara , Messina Andrea , Thorens Bernard , Santoni Federico , Langlet Fanny 
Published: August 2024

AbstractThe ependyma lining the third ventricle (3V) in the mediobasal hypothalamus plays a crucial role in energy balance and glucose homeostasis. It is characterized by a high functional heterogeneity and plasticity, but the underlying molecular mechanisms governing its features are not fully understood. Here, 5481 hypothalamic ependymocytes were cataloged using FACS-assisted scRNAseq from fed, 12h-fasted, and 24h-fasted adult male mice. With standard clustering analysis, typical ependymal cells and β2-tanycytes appear sharply defined, but other subpopulations, β1- and α-tanycytes, display fuzzy boundaries with few or no specific markers. Pseudospatial approaches, based on the 3V neuroanatomical distribution, enable the identification of specific versus shared tanycyte markers and subgroup-specific versus general tanycyte functions. We show that fasting dynamically shifts gene expression patterns along the 3V, leading to a spatial redistribution of cell type-specific responses. Altogether, we show that changes in energy status induce metabolic and functional switches in tanycyte subpopulations, providing insights into molecular and functional diversity and plasticity within the tanycyte population.
Magnetic order in the computational 2D materials database (C2DB) from high throughput spin spiral calculations
Authors: Sødequist Joachim , Olsen Thomas 
Published: August 2024

AbstractWe report high throughput computational screening for magnetic ground state order in 2D materials. The workflow is based on spin spiral calculations and yields the magnetic order in terms of a two-dimensional ordering vector Q. We then include spin-orbit coupling to extract the easy and hard axes for collinear structures and the orientation of spiral planes in non-collinear structures. Finally, for all predicted ferromagnets we compute the Dzyaloshinskii-Moriya interactions and determine whether or not these are strong enough to overcome the magnetic anisotropy and stabilise a chiral spin spiral ground state. We find 58 ferromagnets, 21 collinear anti-ferromagnets, and 85 non-collinear ground states of which 15 are chiral spin spirals driven by Dzyaloshinskii-Moriya interactions. The results show that non-collinear order is in fact as common as collinear order in these materials and emphasise the need for detailed investigation of the magnetic ground state when reporting magnetic properties of new materials.
Distance-depending transcriptome changes of pancreatic stellate cells in paracrine pancreatic ductal adenocarcinoma co-culture models
Authors: Zourelidis Anais , Trojanowicz Bogusz , Sunami Yoshiaki , Hause Gerd , Vieweg David , Kleeff Jörg 
Published: August 2024

AbstractPancreatic stellate cells (PSC) are one source of cancer-associated fibroblasts (CAF) and play, therefore, an essential role in pancreatic ductal adenocarcinoma (PDA). Paracrine signalling between PDA cells and CAF has been widely studied, yet external influences on paracrine crosstalk are poorly understood. This study aimed to gain a deeper insight into the communication of PSC and cancer cells under different co-culture conditions via analysis of PSC gene expression profiles. Two contactless co-culture models with tumor cells from the p48-Cre; lox-stop-lox-KrasG12D/+; lox-stop-lox-Trp53R172H/+ mouse model (KPC) and murine PSC separated through a microporous membrane and grown in different compartments (standard co-culture) or on different sides of the same membrane (inverse co-culture), were established. RNA-Sequencing analysis of PSC mRNA was performed 24 h and 72 h after co-culture with KPC cells. For selected genes, results were confirmed by quantitative RT-PCR and immunocytochemistry. Standard co-culture displayed 19 differentially expressed genes (DEG) at 24 h and 52 DEG at 72 h. In inverse co-culture, 800 DEG at 24 h and 2213 DEG at 72 h were enriched. PSC showed great heterogeneity in their gene expression profiles; however, mutually regulated genes of both co-cultures, such as VCAN and CHST11, could be identified. VCAN-protein–protein interaction-network analysis revealed several shared genes between co-culture models, such as SDC4 and FN1. In conclusion, PSC show a varying susceptibility to cancer cell signals depending on the co-culture method, with intensified transcriptome changes with closer proximity.
Trust value evaluation of cloud service providers using fuzzy inference based analytical process
Authors: John Jomina , John Singh K. 
Published: August 2024

AbstractUsers can purchase virtualized computer resources using the cloud computing concept, which is a novel and innovative way of computing. It offers numerous advantages for IT and healthcare industries over traditional methods. However, a lack of trust between CSUs and CSPs is hindering the widespread adoption of cloud computing across industries. Since cloud computing offers a wide range of trust models and strategies, it is essential to analyze the service using a detailed methodology in order to choose the appropriate cloud service for various user types. Finding a wide variety of comprehensive elements that are both required and sufficient for evaluating any cloud service is vital in order to achieve that. As a result, this study suggests an accurate, fuzzy logic-based trust evaluation model for evaluating the trustworthiness of a cloud service provider. Here, we examine how fuzzy logic raises the efficiency of trust evaluation. Trust is assessed using Quality of Service (QoS) characteristics like security, privacy, dynamicity, data integrity, and performance. The outcomes of a MATLAB simulation demonstrate the viability of the suggested strategy in a cloud setting.
Koku Sensation and Kokumi Substance: New Opportunities to Increase Palatability in Plant-Based Products
Authors: Valerón Nabila Rodríguez 
Published: August 2024

Abstract
Food production needs to increase by 70% to meet the rising demand, but this puts a strain on food quality standards. Continuing to produce food in the same way would require more than one planet to sustain the demand, which is not feasible. Another problem is food waste; one-third of human food production is wasted globally every year, and only a small percentage is used for animal feed or other purposes. Therefore, drastic changes must be made to the global food production systems and our eating habits. Researchers have suggested a planetary diet that involves increasing the consumption of vegetables and fruits while reducing the intake of red meat. The goal is to accelerate the shift towards a greener lifestyle without compromising taste. It is suggested that koku sensation and kokumi substance can be effective tools for developing healthy and sustainable food by enhancing the taste of plant-based products. Research shows that fermentation is a promising method for improving the desirable qualities of plant-based foods by increasing the presence of kokumi peptides and various aroma compounds during the transformation process of raw materials, such as cereal by-products. This field of study holds the potential to increase consumer preference for plant-based diets by reducing unpleasant tastes, such as bitterness.

Information
© The Author 2024
Mode Multiplication of Cylindrical Vector Beam Using Raytracing Control
Authors: Wang 王 Jing 晶 , Zeng 曾 Qingji 庆计 , Wu 吴 Haisheng 海生 , Xie 谢 Chuangxin 创鑫 , Ye 叶 Huapeng 华朋 , Dong 董 Ze 泽 , Fan 范 Dianyuan 滇元 , Chen 陈 Shuqing 书青 
Published: August 2024

Abstract
Cylindrical vector beams (CVBs) hold significant promise in mode division multiplexing communication owing to their inherent vector mode orthogonality. However, existing studies for facilitating CVB channel processing are confined to mode shift conversions due to their reliance on spin-dependent helical modulations, overlooking the pursuit of mode multiplication conversion. This challenge lies in the multiplicative operation upon inhomogeneous vector mode manipulation, which is expected to advance versatile CVB channel switching and routing. Here, we tackle this gap by introducing a raytracing control strategy that conformally maps the light rays of CVB from the whole annulus distribution to an annular sector counterpart. Incorporated with the multifold conformal annulus-sector mappings and polarization-insensitive phase modulations, this approach facilitates the parallel transformation of input CVB into multiple complementary components, enabling the mode multiplication conversion with protected vector structure. Serving as a demonstration, we experimentally implemented the multiplicative operation of four CVB modes with the multiplier factors of N = +2 and N = –3, achieving the converted mode purities over 94.24% and 88.37%. Subsequently, 200 Gbit/s quadrature phase shift keying signals were successfully transmitted upon multiplicative switching of four CVB channels, with the bit-error-rate approaching 1 × 10−6. These results underscore our strategy’s efficacy in CVB mode multiplication, which may open promising prospects for its advanced applications.
Roadmap on specialty optical fibers
Authors: Ferreira Mário F S , Rehan Mohd , Mishra Vishwatosh , Varshney Shailendra Kumar , Poletti Francesco , Phuoc Trung Hoa Nguyen , Wang Weichao , Zhang Qinyuan , Du Wenyu , Yu Benli , Hu Zhijia , Feng Xian , Shi Jindan , Anjali  , Kumar Sunil , Kamrádek Michal , Paul Mukul Chandra , Abedin Kazi , Kibler Bertrand , Smektala Frédéric , Zhu Xiushan , Pryamikov Andrey , Reitzenstein Stephan 
Published: August 2024

Abstract
Optical fibers, long an enabling technology for telecommunications, are proving to play a central role in a growing number of modern applications, starting from high speed broad band internet to medical surgery and entering across the entire spectrum of scientific, military, industrial and commercial applications. Specialty optical fibers either special waveguide structure or novel material composition becomes heart of all fiber based advanced photonics devices and components. This rapidly evolving field calls on the expertise and skills of a broad set of different disciplines: materials science, ceramic engineering, optics, electrical engineering, physics, polymer chemistry, and several others. This roadmap on specialty optical fibers addresses different technologies and application areas. It is constituted by fourteen contributions authored by world-leading experts, providing insight into the current state-of-the-art and the challenges their respective fields face. Some articles address the area of multimode fibers, including the nonlinear effects occurring in them. Several other articles are dedicated to doped, plastic, and soft-glass fibers. Large mode area fibers, hollow-core fibers, and nanostructured fibers are also described in different sections. The use of some of such fibers for optical amplification and to realize several kinds of optical sources—including lasers, single photon sources and supercontinuum sources—is described in some other sections. Different approaches to satisfy applications at visible, infrared and terahertz spectra regions are also discussed. Throughout the roadmap there is an attempt to foresee and to suggest future directions in this particularly dynamic area of optical fiber technology.
To eat or not to eat: novel stable isotope models reveal a shift in carnivory with nutrient availability for aquatic Utricularia spp.
Authors: Kurosawa Emmi , Wells Naomi S , Gibson Robert , Lyons Zachary , Kesseli Richard , Oakes Joanne M 
Published: August 2024

Abstract

Background and Aims
Freshwater nitrogen inputs are increasing globally, altering the structure and function of wetland ecosystems adapted to low nutrient conditions. Carnivorous wetland plants of the genus Utricularia are hypothesized to reduce their reliance on carnivory and increase their assimilation of environmental nutrients when the supply of ambient nutrients increases. Despite success in using stable isotope approaches to quantify carnivory of terrestrial carnivorous plants, quantifying carnivory of aquatic Utricularia requires improvement.

Methods
We developed stable isotope mixing models to quantify aquatic plant carnivory and used these models to measure dietary changes of three Utricularia species, Utricularia australis, U. gibba and U. uliginosa, in 11 wetlands across a 794-km gradient in eastern Australia. Diet was assessed using multiple models that compared variations in the natural-abundance nitrogen isotope composition (δ15N) of Utricularia spp. with that of non-carnivorous plants, and environmental and carnivorous nitrogen sources.

Key Results
Carnivory supplied 40–100 % of plant nitrogen. The lowest carnivory rates coincided with the highest availability of ammonium and dissolved organic carbon.

Conclusions
Our findings suggest that Utricularia populations may adapt to high nutrient environments by shifting away from energetically costly carnivory. This has implications for species conservation as anthropogenic impacts continue to affect global wetland ecosystems.
A synopsis of Carex subgenus Psyllophorae, sect. Junciformes (Cyperaceae) in South America
Authors: Morales-Alonso Ana , Muñoz-Schüler Paulo , Pereira-Silva Luciana , Donadío Sabina , Martín-Bravo Santiago , Jiménez-Mejías Pedro 
Published: August 2024

Abstract
This is the second study of a series of thorough studies into the taxonomy and systematics of Carex in South America. Here, we present the systematic placement, taxonomic account, formal typifications, and summarized distributions for the 31 accepted South America species of Carex subg. Psyllophorae, all belonging to sect. Junciformes. We have conducted an exhaustive revision of literature, more than 400 specimens from 32 South and North American and European herbaria have been studied, and a Sanger phylogenetic study with four DNA regions and morphometric analyses for the C. phalaroides group have been performed. We present an enlarged phylogenetic study where sect. Junciformes sampling has increased by 11 species regarding previous studies, only lacking four species of the group (C. herba-alpacae, C. moorei, C. nelmesiana, and C. transandina). South American species of sect. Junciformes are grouped into four major lineages: C. camptoglochin Clade, Aciculares Clade (South America and Australia–New Zealand), C. phalaroides group, and Junciformes Clade. We have resolved the C. phalaroides complex into six independent species with a clear geographic structure. We successfully unravelled the systematic placement of three species included here for the first time (C. boelckeiana, C. reicheana, and C. manuelbarrosii). An identification key is provided for the studied species. We propose 30 new typifications, and four new species are described (C. herba-alpacae, C. manuelbarrosii, C. melliza, and C. via-montana).
Treatment of Hailey–Hailey disease with biologics and small-molecule inhibitors: a systematic review
Authors: Liu Wei , Xue Xiao , Li Shanshan 
Published: August 2024

Abstract
Hailey–Hailey disease (HHD) is a rare genetic dermatosis characterized by recurrent flaccid vesicles and blisters on erythematous skin in friction areas. The disease follows a chronic relapsing course and has a significant psychological and social impact. Currently, there is no standardized therapeutic regimen for HHD, posing a challenge for dermatologists in managing the condition. We performed this systematic review to investigate the therapeutic role of biologics and small-molecule inhibitors in the treatment of HHD. A systematic search was conducted of the PubMed, Embase, Web of Science, Scopus and Cochrane databases from inception to 1 January 2024. In total, 31 patients with HHD from 18 articles were included in the analysis. Biologics and small-molecule inhibitors were evaluated, including dupilumab, apremilast, upadacitinib, abrocitinib, adalimumab and etanercept. Most reported cases demonstrated clinical improvement after treatment initiation, with few major adverse events. However, some patients experienced recurrences. In conclusion, biologics and small-molecule inhibitors may offer a treatment alternative for patients with refractory HHD, but further confirmation is necessary through large-scale randomized controlled clinical trials.
Viral infections in atopic dermatitis
Authors: Khalil Nada , Walton Joshua , Roberts Nerys , Hussain Khawar 
Published: August 2024

Abstract
Individuals with atopic dermatitis are susceptible to frequent viral skin infections due to compromised epidermal barrier function and immune dysregulation. The diagnosis and management of viral infections in atopic dermatitis can be challenging due to various clinical phenotypes and overlapping clinical features. We reviewed the literature for the diagnosis, aetiology, management, differential diagnoses and complications of these viral infections to provide an up-to-date clinical overview for clinicians involved in caring for patients with atopic dermatitis, including features specific to patients with skin of colour. Accurate diagnosis and appropriate management in cases of uncertainty are crucial due to the risk of life-threatening complications with some viral infections. The differing presentations of these infections in patients with skin of colour are highlighted, as this is an underrepresented area of research. Future research with greater diversity of patients is needed for patients with atopic dermatitis complicated by viral skin infections.