bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tropospheric ozone reduces carbon assimilation in trees: estimates from analysis of continuous flux measurements
Authors: Fares Silvano , Vargas Rodrigo , Detto Matteo , Goldstein Allen H. , Karlik John , Paoletti Elena , Vitale Marcello 
Published: April 2013

AbstractHigh ground‐level ozone concentrations are typical of Mediterranean climates. Plant exposure to this oxidant is known to reduce carbon assimilation. Ozone damage has been traditionally measured through manipulative experiments that do not consider long‐term exposure and propagate large uncertainty by up‐scaling leaf‐level observations to ecosystem‐level interpretations. We analyzed long‐term continuous measurements (>9 site‐years at 30 min resolution) of environmental and eco‐physiological parameters at three Mediterranean ecosystems: (i) forest site dominated by Pinus ponderosa in the Sierra Mountains in California, USA; (ii) forest site composed of a mixture of Quercus spp. and P. pinea in the Tyrrhenian sea coast near Rome, Italy; and (iii) orchard site of Citrus sinensis cultivated in the California Central Valley, USA. We hypothesized that higher levels of ozone concentration in the atmosphere result in a decrease in carbon assimilation by trees under field conditions. This hypothesis was tested using time series analysis such as wavelet coherence and spectral Granger causality, and complemented with multivariate linear and nonlinear statistical analyses. We found that reduction in carbon assimilation was more related to stomatal ozone deposition than to ozone concentration. The negative effects of ozone occurred within a day of exposure/uptake. Decoupling between carbon assimilation and stomatal aperture increased with the amount of ozone pollution. Up to 12–19% of the carbon assimilation reduction in P. ponderosa and in the Citrus plantation was explained by higher stomatal ozone deposition. In contrast, the Italian site did not show reductions in gross primary productivity either by ozone concentration or stomatal ozone deposition, mainly due to the lower ozone concentrations in the periurban site over the shorter period of investigation. These results highlight the importance of plant adaptation/sensitivity under field conditions, and the importance of continuous long‐term measurements to explain ozone damage to real‐world forests and calculate metrics for ozone‐risk assessment.
Experimental determination of CePO4 and YPO4 solubilities in H2O–NaF at 800°C and 1 GPa: implications for rare earth element transport in high‐grade metamorphic fluids
Authors: Tropper P. , Manning C. E. , Harlov D. E. 
Published: April 2013

AbstractMonazite (CePO4) and xenotime (YPO4) are important accessory minerals in metasediments. They host significant rare earth elements (REE) and are useful for geochronology and geothermometry, so it is essential to understand their behavior during the metasomatic processes that attend high‐grade metamorphism. It has been proposed that F‐bearing fluids enhance solubility and mobility of REE and Y during high‐grade metamorphism. We assessed this possibility by determining the solubility of synthetic CePO4 and YPO4 crystals in H2O–NaF fluids at 800°C and 1 GPa. Experiments used hydrothermal piston‐cylinder and weight‐loss methods. Compared to the low solubilities of CePO4 and YPO4 in pure H2O (0.04 ± 0.04 and 0.25 ± 0.04 millimolal, respectively), our results indicate an enormous increase in the solubility of both phosphates with increasing NaF concentration in H2O: CePO4 solubility reaches 0.97 molal in 20 mol.% NaF, and YPO4 shows an even stronger solubility enhancement to 0.45 molal in only 10 mol.% NaF. The greatest relative solubility increases occur at the lowest NaF concentration. The solubilities of CePO4 and YPO4 show similar quadratic dependence on NaF, consistent with possible dissolution reactions of: CePO4 + 2NaF = CeF2+ + Na2PO4− and YPO4 + 2NaF = YF2+ + Na2PO4−. Solubilities of both REE phosphates are significantly greater in NaF than in NaCl at equivalent salt concentration. A fluid with 10 mol.% NaCl and multiply saturated with fluorite, CePO4, and YPO4 would contain 1.7 millimolal Ce and 3.3 millimolal Y, values that are respectively 2.1–2.4 times greater than in NaCl‐H2O alone. The results indicate that Y, and by extension heavy rare earth elements (HREE), can be fractionated from LREE in fluorine‐bearing saline brines which may accompany granulite‐facies metamorphism. The new data support previous indications that REE/Y mobility at these conditions is enhanced by complexing with F in the aqueous phase.
Geochemical simulations to assess the fluorine origin in Sierra de Gador groundwater (SE Spain)
Authors: Daniele L. , Corbella M. , Vallejos A. , Díaz‐Puga M. , Pulido‐Bosch A. 
Published: April 2013

AbstractSierra de Gádor is a complex, Triassic age aquifer system formed by dolostones and limestones with interbedded gypsum. On top, a thick Neogene‐Quaternary series gives rise to shallow aquifers. F‐Pb‐Zn stratabound deposits are found within the Triassic carbonate formations. Their mineral paragenesis includes sphalerite, galena, pyrite, marcasite, fluorite and barite. The Sierra de Gádor groundwater is the principal water resource for this semiarid environment, and the population is potentially exposed to hazardous elements related to mining activities and wastes. In October 1966, an intensive precipitation event (190 mm day−1) broke several old tailing structures, flooding part of the Berja village with polluted sludge. Fluorine values in some boreholes and springs were found higher than 1.5 mg l−1, the maximum value permitted by Spanish regulation for human consumption. Hydrogeochemistry data, statistical tools and geochemical simulations were used in this study to assess the physicochemical processes and the fluorine sources within this carbonate aquifer. Most of the analysed water samples are close to equilibrium with respect to carbonate minerals but are undersaturated with respect to fluorite and gypsum. About 39% of the samples have fluorine concentration higher than the regulatory limit. A statistical analysis indicates that fluorine has a low correlation with other variables. Inverse and mixing models, performed with the code PHREEQC, differentiate the predominance of water–rock interaction processes within the carbonate aquifer and water mixing between the carbonate and shallow aquifers. The results indicate that some fluorite dissolution must occur in the carbonate Triassic aquifer, whereas the shallow aquifers leach fluorine from mining wastes. Both types of aquifers are interconnected, and their waters mix below the flooded area. There, the high fluorine values appear to have two sources: (i) the regional fluorine enrichment due to the mineralization; and (ii) the polluted 1966 flood that reached the deep carbonates via the shallow aquifer.
Interleukin‐33 exacerbates acute colitis via interleukin‐4 in mice
Authors: Pushparaj Peter N. , Li Dong , Komai‐Koma Mousa , Guabiraba Rodrigo , Alexander James , McSharry Charles , Xu Damo 
Published: April 2013

SummaryInterleukin‐33 (IL‐33) and its receptor ST2 are over‐expressed in clinical colitis tissue. However, the significance of these observations is at present unknown. Significantly, we demonstrate here that IL33 and ST2 are the primary early genes induced in the inflamed colon of BALB/c mice following dextran sulphate sodium (DSS)‐induced experimental ulcerative colitis. Accordingly diarrhoea and DSS‐induced colon inflammation were impaired in ST2−/− BALB/c mice and exacerbated in wild‐type mice by treatment with exogenous recombinant IL‐33, associated respectively with reduced and enhanced expression of chemokines (CXCL9 and CXCL10), and inflammatory (IL‐4, IL‐13, IL‐1, IL‐6, IL‐17) and angiogenic (vascular endothelial growth factor) cytokines in vivo. The exacerbation effect of treatment with recombinant IL‐33 on DSS‐induced acute colitis was abolished in IL‐4−/− BALB/c mice. Hence, IL‐33 signalling via ST2, by inducing an IL‐4‐dependent immune response, may be a major pathogenic factor in the exacerbation of ulcerative colitis.
Indomethacin inhibits eosinophil migration to prostaglandin D2: therapeutic potential of CRTH2 desensitization for eosinophilic pustular folliculitis
Authors: Kataoka Naoko , Satoh Takahiro , Hirai Aiko , Saeki Kazumi , Yokozeki Hiroo 
Published: April 2013

SummaryIndomethacin is a cyclo‐oxygenase inhibitor, and shows therapeutic potential for various eosinophilic skin diseases, particularly eosinophilic pustular folliculitis. One of the unique characteristics of indomethacin is that, unlike other non‐steroidal anti‐inflammatory drugs, it is a potent agonist of chemoattractant receptor‐homologous molecule expressed on T helper type 2 cells (CRTH2), a receptor for prostaglandin D2 (PGD2). This study investigated the pharmacological actions of indomethacin on eosinophil migration to clarify the actual mechanisms underlying the therapeutic effects of indomethacin on eosinophilic pustular folliculitis. Eosinophils exhibited chemokinetic and chemotactic responses to both PGD2 and indomethacin through CRTH2 receptors. Pre‐treatment of eosinophils with indomethacin greatly inhibited eosinophil migration to PGD2 and, to a much lesser extent, to eotaxin (CCL11); these effects could be mediated by homologous and heterologous desensitization of eosinophil CRTH2 and CCR3, respectively, by agonistic effects of indomethacin on CRTH2. Indomethacin also cancelled a priming effect of Δ12‐PGJ2, a plasma metabolite of PGD2, on eosinophil chemotaxis to eotaxin. Indomethacin down‐modulated cell surface expression of both CRTH2 and CCR3. Hair follicle epithelium and epidermal keratinocytes around eosinophilic pustules together with the eccrine apparatus of palmoplantar lesions of eosinophilic pustular folliculitis were immunohistochemically positive for lipocalin‐type PGD synthase. Indomethacin may exert therapeutic effects against eosinophilic skin diseases in which PGD2‐CRTH2 signals play major roles by reducing eosinophil responses to PGD2.
Parental Speech at 6 Months Predicts Joint Attention at 12 Months
Authors: Roberts Siwan , Fyfield Rhiannon , Baibazarova Eugenia , van Goozen Stephanie , Culling John F. , Hay Dale F. 
Published: April 2013

In a prospective longitudinal study of a representative community sample (N = 264), mothers' references to infants' mental states were coded during a topic‐sharing task in the home at 6 months. Joint attention behaviour was assessed in the laboratory at 12 months. Individual joint attention skills (gaze following, gaze alternating, and declarative pointing) were significantly inter‐correlated, with a single factor accounting for 68% of the variance. Mothers' references to infants' mental states at 6 months predicted infants' joint attention at 12 months. The association was not explained by sociodemographic characteristics of the family, the mother's mental state, or by the quantity or acoustic properties of her speech. However, variability in pitch of maternal speech was an independent predictor of the infants' later joint attention skills. Taken together, these findings suggest that mothers' infant‐directed speech fosters infants' attentive participation in topic‐sharing interactions, which in turn provide an important arena in which joint attention skills develop over the first year of life.
Perfect High‐Temperature Plasticity Realized in Multiwalled Carbon Nanotube‐Concentrated α‐Al2O3 Hybrid
Authors: Estili Mehdi , Sakka Yoshio , Wu Wen‐Wen , Nishimura Toshiyuki , Yoshida Hidehiro , Kawasaki Akira 
Published: April 2013

We investigate the high‐temperature compressive deformation behavior of a novel, fully dense and structurally uniform, 20 vol% multiwalled carbon nanotube (MWCNT)–α‐Al2O3 matrix hybrid, which has a strong room‐temperature interfacial shear resistance (ISR) and a unique MWCNT‐concentrated grain‐boundary (GB) structure. We realized a perfect plastic deformation at 1400°C and a rather high initial strain rate of 10−4 s−1 by a low ~30 MPa flow stress, which is contrary to the strain hardening response of fine‐grain monolithic Al2O3. This unique performance in CNT–ceramic system in compression is explained as follows: the concentrated network of individual MWCNTs perfectly withstands the high‐temperature and shear/compressive forces, and strongly preserves the nanostructure of Al2O3 matrix by preventing the dynamic grain growth, even during a large ~44% deformation. Furthermore, the presence of large amount of radially soft/elastic, highly energy‐absorbing MWCNTs in the GB and specially multiple junction areas, and a potentially weak 1400°C‐ISR, could greatly facilitate the GB sliding process (despite the hybrid's strong room‐temperature ISR), as evidenced by the formation of some submicrometer‐scale MWCNT aggregates in GB area, the equiaxed grains and dislocation‐free nanostructure of the deformed hybrid. The results presented here could be attractive for the ceramic forming industry and could be regarded as a reference for oxide systems in which, the GB areas are occupied with soft/elastic, highly energy‐absorbing nanostructures.
Effects of education of paediatric patients undergoing elective surgical procedures on their anxiety – a systematic review
Authors: Copanitsanou Panagiota , Valkeapää Kirsi 
Published: April 2013

Aims and objectivesTo identify and critically appraise studies addressing the implementation of education for children aged 2–12 years undergoing elective surgical procedures and to determine whether education is associated with improvements in children's anxiety and other emotions.BackgroundChildren undergoing surgery often experience anxiety, which may lead to negative health outcomes, such as increased pain, feeding difficulties and sleeping problems. Education of children about their condition according to their individual needs may be correlated with reduced anxiety.DesignSystematic review.MethodsA database search in MEDLINE, PsycInfo, Cochrane Library and CINAHL was carried out during February 2011. Using the PICOS acronym, the query was organised into a searchable foreground question: the studies should evaluate (Objective) the effects of education (Intervention) compared with the standard preparation (Control) for children aged 2–12 years old undergoing elective surgeries (Population). The results would be based on randomised controlled studies (Study design). In total, 475 articles were yielded, from which 45 full‐text articles were assessed for eligibility, and finally, 16 studies were included in the review.ResultsIn 12 of the 16 studies, children in the education groups reported lower anxiety scores. In two studies, no statistically significant effect of education was reported on anxiety. Moreover, education had an age‐related effect in two studies, by being more effective to children older than four to six years and having a negative effect on younger children's anxiety. Parents of children in the education groups experienced lower anxiety.ConclusionsEducation seems to be especially effective in the reduction in older children's anxiety and to have a negative effect on younger children's anxiety.Relevance to clinical practiceEducation can be incorporated into the care provided to children aged four to six years or older undergoing elective surgical procedures, according to their individualised needs.
Patient experience with bedpans in acute care: a cross‐sectional study
Authors: Gattinger Heidrun , Werner Birgit , Saxer Susi 
Published: April 2013

Aims and objectivesTo describe individual experiences of patients using the bedpan in an acute care setting.BackgroundPatients describe the use of the bedpan often as uncomfortable and painful, and nurses mention difficulties using standard‐sized bedpans for obese patients or removing a bedpan without soiling the bed. Although the bedpan is still regularly used in hospitals, there are few empirical studies that confirm these experiences.DesignA descriptive quantitative research design.MethodsA convenience sample of 78 patients was recruited, and data were collected using a standardised questionnaire (German version of the Bedpan Ongemak Schaal). Descriptive statistics were used to analyse frequency (scale A) and extent of inconvenient experiences (scale B). Internal consistency of the scales was tested using Cronbach's alpha.ResultsA major finding of the study was that most patients felt dependent on other persons and no autonomous movement was possible on the bedpan. Patients were frequently confronted with pain, inconvenient characteristics of the bedpan (e.g. coldness, hardness), uncomfortable positions and hygiene inconveniences (e.g. wet backside, fear that urination may miss the bedpan).ConclusionAs the bedpan is still regularly used in acute care hospitals, innovations in bedpan models are necessary to address the problems. But there are also several courses of action nurses should consider when caring for patients who are dependent on the bedpan.Relevance for clinical practiceThe discomfort of the bedpan, the feeling of dependency and embarrassment could lead to undesirable patient reactions, such as avoidance of fluid intake or leaving the bed. If nurses know the reasons for this behaviour, they could meet these problems with empathetic understanding.
Wittgenstein, Religious “Passion,” and Fundamentalism
Authors: Plant Bob 
Published: April 2013

AbstractNotwithstanding his own spiritual inadequacies, Wittgenstein has a profound respect for those capable of living a genuinely religious life; namely, those whose “passionate,” “loving” faith demands unconditional existential commitment. In contrast, he disapproves of those who see religious belief as hypothetical, reasonable, or dependent on empirical evidence. Drawing primarily on Culture and Value, “Lectures on Religious Belief,” and On Certainty, in this essay I defend two claims: (1) that there is an unresolved tension between Wittgenstein's later descriptive‐therapeutic approach and the implicit normativity of his conception of genuine/passionate religious belief; and (2) that the demarcation between the latter and its pseudo‐religious counterpart is itself problematic. To illustrate these claims I argue that apocalyptic Christian fundamentalism presents a significant challenge to Wittgenstein's taxonomy. Despite these shortcomings, however, I conclude by suggesting that his characterization of religious belief as a “passion” or “love” remains valuable.
Medical Manichaeism
Authors: Campbell Austin L. 
Published: April 2013

AbstractMedical discourse in the contemporary United States is rife with military metaphors. These metaphors have come under vigorous criticism over the last few decades but to no avail; the militaristic tendency has proven tenacious. This essay suggests that its tenacity stems, at least in part, from a dualistic understanding of medicine unaddressed by prior criticisms. For an alternative, this essay turns to Augustine of Hippo, balancing close readings of works that deal explicitly with medical themes—The Catholic Way of Life and the Manichean Way of Life (De moribus) and The Nature of the Good (De natura boni)—with a constructive approach. By adapting Augustine's privative account of evil, we can understand disease as a condition of loss and treatment as a task of restoration. This reconfiguration shifts the focus of our interpretive discourses from malicious invaders to a fuller affirmation of the lived experiences of those who are ill.
Re‐embedding Moral Agency
Authors: Steck Christopher 
Published: April 2013

AbstractThe connection between ethics and theological vision has become increasingly important for ethics as we better appreciate how the moral agent is embedded in a framework that affectively and intellectually shapes her moral reasoning. Moral reasoning is always reasoning within (that is, within a moral framework, a religious worldview, and/or a set of ideological commitments). A similar framing occurs in literature, which I refer to as its “horizon.” A literary text's horizon comprises the theological and metaphysical commitments that are implied by the text and that the reader relies on to make sense of it. I suggest that there is a parallel between how moral frameworks and literary horizons operate in that both shape moral judgment. I argue that in using literature as a resource for ethics, the same contemporary currents that have led us to appreciate the embeddedness of moral reasoning should also encourage us to give more careful attention to the theological or metaphysical vision implied by a text. Such a “theo‐ethical” reading of literature provides a richer understanding of particular moral goods and the interplay between those goods and ethical themes like agency, hope, and redemption. I substantiate this claim with a reading of William Blake's Jerusalem: The Emanation of the Giant Albion.
Effects of incremental amounts of fish oil on trans fatty acids and Butyrivibrio bacteria in continuous culture fermenters
Authors: AbuGhazaleh A. A. , Ishlak A. 
Published: April 2013

SummaryPrevious studies have shown that adding fish oil (FO) to ruminant animal diets increased vaccenic acid (VA; t11 C18:1) accumulation in the rumen. Therefore, the objective of this study was to evaluate the effect of dietary FO amounts on selected strains of rumen bacteria involved in biohydrogenation. A single‐flow continuous culture system consisting of four fermenters was used in a 4 × 4 Latin square design with four 9 days consecutive periods. Treatment diets were as follows: (i) control diet (53:47 forage to concentrate; CON), (ii) control plus FO at 0.5% (DM basis; FOL), (iii) control plus FO at 2% (DM basis; FOM) and (iv) control plus FO at 3.5% (DM basis; FOH). Fermenters were fed treatment diets three times daily at 120 g/day. Samples were collected from each fermenter on day 9 of each period at 1.5, 3 and 6 h post‐morning feeding and then composited into one sample per fermenter. Increasing dietary FO amounts resulted in a linear decrease in acetate and isobutyrate concentrations and a linear decrease in acetate‐to‐propionate ratio. Propionate, butyrate, valerate and isovalerate concentrations were not affected by FO supplementation. Concentrations of C18:0 in fermenters linearly decreased, while concentrations of t10 C18:1 and VA linearly increased as dietary FO amounts increased. The concentrations of c9t11 and t10c12 conjugated linoleic acid were not affected by FO supplementation. The DNA abundance for Butyrivibrio fibrisolvens, Butyrivibrio vaccenic acid subgroup, Butyrivibrio stearic acid subgroup and Butyrivibrio proteoclasticus linearly decreased as dietary FO amounts increased. In conclusion, FO effects on trans fatty acid accumulation in the rumen may be explained in part by FO influence on Butyrivibrio group.