bluuebunny/crossref_metadata_2025_split huggingface dataset:
The outcome of the Birmingham Hip Resurfacing in patients aged < 50 years up to 14 years post-operatively
Authors: Matharu G. S. , McBryde C. W. , Pynsent W. B. , Pynsent P. B. , Treacy R. B. C. 
Published: August 2013

We report the long-term survival and functional outcome of the Birmingham Hip Resurfacing (BHR) in patients aged < 50 years at operation, and explore the factors affecting survival. Between 1997 and 2006, a total of 447 BHRs were implanted in 393 patients (mean age 41.5 years (14.9 to 49.9)) by one designing surgeon. The mean follow-up was 10.1 years (5.2 to 14.7), with no loss to follow-up. In all, 16 hips (3.6%) in 15 patients were revised, giving an overall cumulative survival of 96.3% (95% confidence interval (CI) 93.7 to 98.3) at ten years and 94.1% (95% CI 84.9 to 97.3) at 14 years. Using aseptic revision as the endpoint, the survival for men with primary osteoarthritis (n = 195) was 100% (95% CI 100 to 100) at both ten years and 14 years, and in women with primary osteoarthritis (n = 109) it was 96.1% (95% CI 90.1 to 99.9) at ten years and 91.2% (95% CI 68.6 to 98.7) at 14 years. Female gender (p = 0.047) and decreasing femoral head size (p = 0.044) were significantly associated with an increased risk of revision. The median Oxford hip score (OHS, modified as a percentage with 100% indicating worst outcome) at last follow-up was 4.2% (46 of 48; interquartile range (IQR) 0% to 24%) and the median University of California, Los Angeles (UCLA) score was 6.0 (IQR 5 to 8). Men had significantly better OHS (p = 0.02) and UCLA scores (p = 0.01) than women. The BHR provides excellent survival and functional results in men into the second decade, with good results achieved in appropriately selected women.Cite this article: Bone Joint J 2013;95-B:1172–7.
The viability of cells obtained using the Reamer–Irrigator–Aspirator system and in bone graft from the iliac crest
Authors: Uppal H. S. , Peterson B. E. , Misfeldt M. L. , Della Rocca G. J. , Volgas D. A. , Murtha Y. M. , Stannard J. P. , Choma T. J. , Crist B. D. 
Published: August 2013

We hypothesised that cells obtained via a Reamer–Irrigator–Aspirator (RIA) system retain substantial osteogenic potential and are at least equivalent to graft harvested from the iliac crest. Graft was harvested using the RIA in 25 patients (mean age 37.6 years (18 to 68)) and from the iliac crest in 21 patients (mean age 44.6 years (24 to 78)), after which ≥ 1 g of bony particulate graft material was processed from each. Initial cell viability was assessed using Trypan blue exclusion, and initial fluorescence-activated cell sorting (FACS) analysis for cell lineage was performed. After culturing the cells, repeat FACS analysis for cell lineage was performed and enzyme-linked immunosorbent assay (ELISA) for osteocalcin, and Alizarin red staining to determine osteogenic potential. Cells obtained via RIA or from the iliac crest were viable and matured into mesenchymal stem cells, as shown by staining for the specific mesenchymal antigens CD90 and CD105. For samples from both RIA and the iliac crest there was a statistically significant increase in bone production (both p < 0.001), as demonstrated by osteocalcin production after induction. Medullary autograft cells harvested using RIA are viable and osteogenic. Cell viability and osteogenic potential were similar between bone grafts obtained from both the RIA system and the iliac crest. Cite this article: Bone Joint J 2013;95-B:1269–74.
Pseudohypoaldosteronism type 1: clinical features and management in infancy
Authors: Amin N , Alvi N S , Barth J H , Field H P , Finlay E , Tyerman K , Frazer S , Savill G , Wright N P , Makaya T , Mushtaq T 
Published: August 2013

Summary
Type 1 pseudohypoaldosteronism (PHA) is a rare heterogeneous group of disorders characterised by resistance to aldosterone action. There is resultant salt wasting in the neonatal period, with hyperkalaemia and metabolic acidosis. Only after results confirm isolated resistance to aldosterone can the diagnosis of type 1 PHA be confidently made. Type 1 PHA can be further classified into i) renal type 1 (autosomal dominant (AD)) and ii) multiple target organ defect/systemic type 1 (autosomal recessive (AR)). The aim of this case series was to characterise the mode of presentation, management and short-term clinical outcomes of patients with PHA type 1. Case notes of newly diagnosed infants presenting with PHA type 1 were reviewed over a 5-year time period. Seven patients were diagnosed with PHA type 1. Initial presentation ranged from 4 to 28 days of age. Six had weight loss as a presenting feature. All subjects had hyperkalaemia, hyponatraemia, with elevated renin and aldosterone levels. Five patients have renal PHA type 1 and two patients have systemic PHA type, of whom one has had genetic testing to confirm the AR gene mutation on the SCNN1A gene. Renal PHA type 1 responds well to salt supplementation, whereas management of patients with systemic PHA type 1 proves more difficult as they are likely to get frequent episodes of electrolyte imbalance requiring urgent correction.

Learning points

Patients with type 1 PHA are likely to present in the neonatal period with hyponatraemia, hyperkalaemia and metabolic acidosis and can be diagnosed by the significantly elevated plasma renin activity and aldosterone levels.

The differential diagnosis of type 1 PHA includes adrenal disorders such as adrenal hypoplasia and congenital adrenal hyperplasia; thus, adrenal function including cortisol levels, 17-hydroxyprogesterone and a urinary steroid profile are required. Secondary (transient) causes of PHA may be due to urinary tract infections or renal anomalies; thus, urine culture and renal ultrasound scan are required respectively.

A differentiation between renal and systemic PHA type 1 may be made based on sodium requirements, ease of management of electrolyte imbalance, sweat test results and genetic testing.

Management of renal PHA type 1 is with sodium supplementation, and requirements often decrease with age.

Systemic PHA type 1 requires aggressive and intensive fluid and electrolyte management. Securing an enteral feeding route and i.v. access are essential to facilitate ongoing therapy.

In this area of the UK, the incidence of AD PHA and AR PHA was calculated to be 1:66 000 and 1:166 000 respectively.
Ectopic prolactin secretion secondary to an ovarian tumour
Authors: Gururaj Sowmya , Nisal K , Davies Q , Deen S , McNally P G 
Published: August 2013

Summary
Ectopic hormone secretion is a well-recognised phenomenon; however, ectopic prolactin secretion is exceptionally rare. Hoffman and colleagues reported the first ever well-documented case of ectopic prolactin secretion secondary to a gonadoblastoma. We report a lady who presented with galactorrhoea and a large ovarian tumour that was found to secrete high levels of prolactin.

Learning points

Aim of this case report is to highlight the occurrence of this condition.

Lack of awareness can often lead to a diagnostic conundrum.
Industrial Distributions of Severe Occupational Injuries among Workers in Thailand
Authors: Yamakawa Michiyo , Sithisarankul Pornchai , Yorifuji Takashi , Hengpraprom Sarunya , Hiransuthikul Narin , Doi Hiroyuki , Takao Soshi 
Published: August 2013

Industrial Distributions of Severe Occupational Injuries among Workers in Thailand: Michiyo YAMAKAWA, et al. Department of Epidemiology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University—BackgroundIn industrializing countries, occupational safety and health have been affected by globalization. However, a lack of reliable data prevents evaluation of this situation. Therefore, we examined industrial distributions and risks of severe occupational injuries among workers in Thailand, which is one of the few industrializing countries that compiles nationwide data.MethodsData on workers who made claims for occupational injuries from 2007 to 2009 were extracted from the Workmen's Compensation Fund records in Thailand. Among 501,334 claimants, we evaluated the industrial distributions of severe occupational injuries (i.e., permanent disability and death). We then examined the associations between industry and those injuries, using proportionate ratios (PRs) between each industrial category and the overall distribution of occupational injuries.ResultsThe number of workers in manufacturing making claims for severe occupational injuries was the largest among all industrial categories (319,114/501,334 injuries), although the total number of occupational injuries recently declined. Additionally, workers in manufacturing experienced severe occupational injuries more often compared with the overall distribution of occupational injuries. The PRs (95% confidence interval) for manufacturing were 1.17 (1.14−1.20) in men and 1.33 (1.27−1.38) in women. After adjusting for individual characteristics, the results did not substantially change.ConclusionsManufacturing seems to have the largest burden of occupational injuries in industrializing countries like Thailand.
Information and Heterogeneous Beliefs: Cost of Capital, Trading Volume, and Investor Welfare
Authors: Christensen Peter O. , Qin Zhenjiang 
Published: August 2013

ABSTRACT
In an incomplete market with heterogeneous prior beliefs, we show that public information can have a substantial impact on the ex ante cost of capital, trading volume, and investor welfare. The Pareto efficient public information system is the system enjoying the maximum ex ante cost of capital and the maximum expected abnormal trading volume. Imperfect public information increases the gains-to-trade based on heterogeneously updated posterior beliefs. In an exchange economy, this leads to higher growth in the investors' certainty equivalents and, thus, a higher equilibrium interest rate, whereas the ex ante risk premium is unaffected by the informativeness of the public information system. Similar results are obtained in a production economy, but the impact on the ex ante cost of capital is dampened compared to the exchange economy due to welfare-improving reductions in real investments to smooth the investors' certainty equivalents over time.
Human hydatidosis: an under discussed occupational zoonosis in India
Authors: Singh B. , Singh G. , Sharma R. , Sharma J. , Aulakh R. , Gill J. 
Published: August 2013

Abstract
Human hydatidosis is an important public health issue in India and many other developing countries. There is lack of data related to occurrence of this disease in certain risk groups. The present study was therefore designed to assess the seroprevalence of human hydatidosis among occupational risk groups in Punjab (India). One hundred and forty nine human serum samples from dog handlers, veterinarians/para veterinarians, dairy farmers, patients with liver disorders, HIV positives and control group (visiting hospital for other problems) were collected and analyzed using a commercially available enzyme linked immunosorbent assay (ELISA). The results revealed that 23 (15.43 %) subjects were seropositive for human hydatidosis. High seropositivity were recorded in dog handlers (30 %), followed by the other risk group populations. Relative risk of being infected was found to be 4.80 times high in dog handlers when compared to control group population. Future studies must be planned to determine the significance of these findings and the status of human hydatidosis in India.
Mesothelial metaplasia in European pond turtle, Emys orbicularis (Testudines: Emydidae) infected with Spiroxys contortus (Nematoda: Spirurida)
Authors: Miclăuş V. , Mihalca A. , Gal A. , Cătoi C. 
Published: August 2013

Abstract
The mesothelium consists of a monolayer of specialized epithelial cells that line the surfaces of the peritoneal, pleural, and pericardial cavities. The present study reports mesothelial changes associated with larval stages of the spirurid nematode Spiroxys contortus in a naturally infected European pond turtle. Between 2002 and 2007, eight European pond turtle, Emys orbicularis were brought for necropsy. In one adult male turtle, necropsy revealed the presence of gastric and mesothelial changes associated with gastric infestation with the nematode Spiroxys contortus. Gastrointestinal samples with gross lesions were collected and processed by paraffin technique for further histological examination. Mesothelial cuboidal to columnar or pseudostratified focal progressive metaplasia was observed in visceral coelomic cavity. Intracytoplasmic acidophilic hyaline inclusions were also observed in metaplastic mesothelial cells, most of them being placed to the apical cell’s poles. The significance of our findings is discussed in the light of current knowledge regarding the mesothelial cells.
Biofeedback to Promote Movement Symmetry After Total Knee Arthroplasty: A Feasibility Study
Authors: Zeni Joseph , Abujaber Sumayah , Flowers Portia , Pozzi Federico , Snyder-Mackler Lynn 
Published: August 2013

Study Design Prospective analysis of a longitudinal cohort with an embedded comparison group at a single time point. Objectives To determine the feasibility and effectiveness of an outpatient rehabilitation protocol that includes movement symmetry biofeedback on functional and biomechanical outcomes after total knee arthroplasty (TKA). Background TKA reduces pain and improves functional ability, but many patients experience strength deficits and movement abnormalities in the operated limb, despite outpatient rehabilitation. These asymmetries increase load on the nonoperated limb, and greater asymmetry is related to worse functional outcomes. Methods Biomechanical and functional metrics were assessed 2 to 3 weeks prior to TKA, at discharge from outpatient physical therapy, and 6 months after TKA in 11 patients (9 men, 2 women; mean ± SD age, 61.4 ± 5.8 years; body mass index, 33.1 ± 5.4 kg/m2) who received 6 to 8 weeks of outpatient physical therapy that included specialized symmetry training. Six-month outcomes were compared to a control group, matched by age, body mass index, and sex (9 men, 2 women; mean ± SD age, 61.8 ± 5 years; body mass index, 34.3 ± 5.1 kg/m2), that did not receive specialized symmetry retraining. Results Of the 11 patients who received added symmetry training, 9 demonstrated clinically meaningful improvements that exceeded the minimal detectable change for all performance-based functional tests at 6 months post-TKA compared to pre-TKA. Six months after TKA, when walking, patients who underwent symmetry retraining had greater knee extension during midstance and had mean sagittal knee moments that were more symmetrical, biphasic, and more representative of normal knee kinetics compared to patients who did not undergo symmetry training. No patients experienced adverse events as the result of the protocol. Conclusion Adding symmetry retraining to postoperative protocols is clinically viable, safe, and may have additional benefits compared to rehabilitation protocols that focus on range of motion, strength, and return to independence. Level of Evidence Therapy, level 4. J Orthop Sports Phys Ther 2013;43(10):715–726. Epub 26 July 2013. doi:10.2519/jospt.2013.4657
Les fouilles de sauvetage de Saint-Maur (Gers)
Authors: Lassure Jean-Michel 
Published: August 2013

Found out during navvying in the named place Le Prieurat, on the site of a bénédictine conuent founded around the 12 th century, three trapezoid burials with a four-angled loggia for the defunct's head were excauated in 1975.
Made of sandstone blocks, joined by lime mortars, thèse burials are extremely long (up to 2,05 m) but their width is precisely calculated. Each is built amidst a wide rectangular pit. They were covered with flatstones arrayed in a transversal way, topped by a covering ofstones bedded in mortar. We could take sever al pièces of a linen which was hung over one of the burials to auoid the defunct being dirtied during the entombment.
Lying on the back, with the arms parallel to the body the skeletons were coated with some fine and dense clay. There was no set of furniture so it is impossible to date these burials. However, their pattern was uery often used probably from the 9 th to the 15 th century.
Numerous fragments of pottery, and bits of glass were found near thèse burials ont the soil turned over by a bulldozer.
Peyremoutou : une verrerie du XVII e siècle dans la Montagne Noire (Tarn)
Authors: Bourrel Bernard , Averous Jean-Claude , Foy Danièle 
Published: August 2013

Le four à verre de Peyremoutou découvert par la fouille est un vestige des nombreux ateliers établis dans la Montagne Noire à l'époque Moderne. Ce four de fusion dont la sole porte encore les marques des creusets, faisait partie d'un ensemble plus complexe que la suite des travaux s'attacheront à révéler.
D'après le matériel archéologique (céramiques, verres et outil) et les textes, cet atelier daté du XVIIe siècle appartenait à la célèbre famille verrière des de Robert. Quelques indices -mali.eureusement hors stratigraphie- laissent supposer une occupation antérieure à l'installation des verriers modernes : des fragments de verre et de céramique médiévaux ne suffisent pas à définir cette occupation.
Découverte de poteries et verres dans le palais cardinalice de la Romieu (Gers)
Authors: Ugaglia Evelyne , Pousthomis Bernard 
Published: August 2013

Au cœur du palais cardinalice de La Romieu, fondé au début du XIVe siècle, ont été découvertes deux fosses contenant un intéressant mobilier céramique et de verre.
La première de ces fosses était comblée par un remplissage organisé par couches mais dont le mobilier semble appartenir à une même époque. Un lot de poteries, dont neuf complètes et en parfait état de conservation, y ont été découvertes. Il s'agit de pots à une anse, panse ventrue, font plat ou légèrement bombé, et de cruches hautes à bec pincé. Ces poteries sont en céramique rouge tournée. Une série de tessons de verre appartenant à des bouteilles, des verres à pied et des gobelets s'y trouvaient également. Les modifications survenues aux bâtiments du palais près de la fosse et la datation par comparaison du mobilier, conduisent à dater ce dernier du bas Moyen Age.
La seconde fosse, bâtie en pierres bien appareillées, était probablement un puits à déchets. Une ouïe, un fond de cruche et une poêle, à cuisson oxydante, tournées et glaçurées, s'y trouvaient. L'étude du contexte archéologique et de ces poteries conduisent à une datation du XIVe ou XVe siècle.
Céramiques d'un dépotoir du XVIe siècle à Avignon
Authors: Carru Dominique 
Published: August 2013

The pieces of ceramic presented, corne from an archaeological site, closed, sealed and precisely dated, discovered in an urban environment. The interest of this material is to extend.for the first half of the XVIth century, the typo-chronological investigations, made about the ceramics of the late Middle Ages, in the Avignon surroundings.
Beyond the list of the varions shapes and qualities of the representated ceramics, the typological evolution, and the fluctuations of the supply sources are considered. This investigation tends to demonstrate that the traditionnal Spanish importations are maintained, besides new Italian products. The directory of the local workshops changes, under Ligurian influences.
Les lieux de culte du diocèse de Saint-Papoul à la fin du Moyen Age
Authors: Marandet Marie-Claude 
Published: August 2013

L'évêché de Saint-Papoul est créé le 11 juillet 1317 par Jean XXII, la bulle de délimitation du diocèse publiée le 22 février 1318 mentionne cinquante églises, chapelles, prieurés ou monastères. L'étude des pouillés, registres notariaux, séries G et H des XIVe et XVe siècles a fait apparaître divers lieux de culte ne figurant pas sur cette liste, multipliant pratiquement leur nombre par trois. L'incertitude est assez fréquente quant au statut des églises mentionnées : églises paroissiales, annexes, simples chapelles ne sont pas toujours discernables.
Les églises rurales sont alors très nombreuses, survivances probables de communautés des Xe et XIe siècles ; certaines de ces églises sont parfois mentionnées au XVe comme étant d'anciennes églises paroissiales. Le cimetière jouxtant l'église paroissiale est de règle mais d'autres cimetières, extérieurs aux agglomérations continuent de fonctionner. Ils sont parfois de fondation récente, liés à des hôpitaux ; le plus souvent, ils sont situés près d'une chapelle rurale, là où un habitat a pu exister antérieurement. L'Eglise s'efforce de les sanctifier en y faisant édifier des chapelles, en y célébrant des offices, généralement celui des Rameaux ; elle le fait clôturer pour le protéger des divagations du bétail- Pendant les XIVe et XVe siècles, cette région est une zone de brigandage où sévissent les routiers. La population, moins nombreuse, est pressurée d'impôt ; on manque d'argent pour entretenir les lieux de culte. L'argent est réservé en priorité à l'église paroissiale. Ceci entraîne la dégradation, parfois la disparition d'églises champêtres, et, même en ville, les édifices sont en mauvais état. Le diocèse de Saint-Papoul apparaît dans un état assez médiocre à la fin du Moyen Age, 10 % des lieux de culte (surtout les chapelles rurales) semblent avoir disparu courant XIVe siècle, toutefois l'essentiel des disparitions s'effectue aux XVIe, XVIIe et XVIIIe siècles.
Etude de l'élévation de l'église Notre-Dame du Val des Nymphes (commune de La Garde-Adhémar, Drôme)
Authors: Vaireaux François 
Published: August 2013

This article presents an elevation study of the romanesque church Notre-Dame du Val des Nymphes (parish ofLa Garde-Adhémar, Drôme), which shows, "piece-worker marks ", as do most of the south-eastern remains of the romanesque art.
After the historical record of the place and of the church, the corpus and the interpretation of these marks, the author presents in seven steps of work, the evolution of the building, by the reconstitution of the association of these marks, in accordance with the successive teams of stone cutters, and tries to specify the organisation of the romanesque building site.
L'abbaye d'Aniane en Languedoc. Des Mauristes à l'établissement pénitentiaire
Authors: Durand Geneviève 
Published: August 2013

A plan to extend the terms for the protection of historical monuments covering the block of Abbey buildings at Aniane, enabled us to carry out an archivist study and gives with precision the chronology ofethe different series building campaigns.
Of the medieval Abbey there is no trace left today. The arrival of the Maurists in the year 1635 overthrew the site ; the old buildings were razed to the ground, and the space inside the monastic enclosure was reorganized. The Saint-Sauveur church in the North, the adjoining cloister in the South and the four main buildings were then rebuilt. Work began in the second half ofthe XVIIth century (western main building and church), and continued until the Revolution, apparently respecting the original pattern. At the Revolution theAbbey was sold. The church became a parish church whereas the old monastery buildings where successively transformed into a cotton mill, then into a detention house in the year 1845. This new assignment did not spoil the monument ; only the heightening of the western main housing is noticeable, as well as the extension of the building eastwards and a complete refitting of the inside space. In spite ofeall these vicissitudes, the Aniane Abbey remains one of the rare complete examples of the monastic architecture in Languedoc under the old regime (before 1789).