bluuebunny/crossref_metadata_2025_split huggingface dataset:
An initial model construction method constrained by stratigraphic sequence representation for pre‐stack seismic inversion
Authors: Chen Ting , Zou Bangli , Wang Yaojun , Cai Hanpeng , Yu Gang , Hu Guangmin 
Published: July 2024

AbstractThe construction of an accurate and high‐resolution reservoir parameter model is crucial for reservoir characterization. However, due to the band‐limited characteristics of seismic data, the inversion results heavily rely on the accuracy of the initial model. Most existing techniques for constructing an initial model interpolate well logging data within the stratigraphic framework, neglecting the effect of the stratigraphic sequence, which compromises the reliability of the initial model. The stratigraphic sequence is essential for dividing stratigraphic evolution stages and defining a geological relationship between reservoirs within the stratigraphic framework. Therefore, an initial model construction method constrained by stratigraphic sequence representation is proposed for pre‐stack seismic inversion. The process begins with establishing the stratigraphic framework using horizon and fault data. Subsequently, the collaborative sparse representation algorithm is used to learn a joint dictionary that captures the relationship of structural features between seismic data and stratigraphic sequence from the well logging data. In the process of seismic data representation, the stratigraphic sequence is accurately represented in three‐dimensional space by sharing sparse coefficients in the joint dictionary. Finally, the elastic parameter model is constructed by integrating the stratigraphic framework, stratigraphic sequence and well logging data, providing a reliable initial model for pre‐stack seismic inversion. The main innovation of the proposed method is the three‐dimensional representation of the stratigraphic sequence. A synthetic example demonstrates that the proposed method produces a more accurate initial model than conventional interpolation methods. Additionally, when applied to field data, it yields satisfactory results even without complete S‐wave velocity well logging data.
Estimating encounter‐habitat relationships with scale‐integrated resource selection functions
Authors: Egan Michael E. , Gorman Nicole T. , Crews Storm , Eichholz Michael W. , Skinner Dan , Schlichting Peter E. , Rayl Nathaniel D. , Bergman Eric J. , Ellington E. Hance , Bastille‐Rousseau Guillaume 
Published: June 2024

Abstract

Encounters between animals occur when animals are close in space and time. Encounters are important in many ecological processes including sociality, predation and disease transmission. Despite this, there is little theory regarding the spatial distribution of encounters and no formal framework to relate environmental characteristics to encounters. The probability of encounter could be estimated with resource selection functions (RSFs) by comparing locations where encounters occurred to available locations where they may have occurred, but this estimate is complicated by the hierarchical nature of habitat selection.

We developed a method to relate resources to the relative probability of encounter based on a scale‐integrated habitat selection framework. This framework integrates habitat selection at multiple scales to obtain an appropriate estimate of availability for encounters. Using this approach, we related encounter probabilities to landscape resources. The RSFs describe habitat associations at four scales, home ranges within the study area, areas of overlap within home ranges, locations within areas of overlap, and encounters compared to other locations, which can be combined into a single scale‐integrated RSF. We apply this method to intraspecific encounter data from two species: white‐tailed deer (Odocoileus virginianus) and elk (Cervus elaphus) and interspecific encounter data from a two‐species system of caribou (Rangifer tarandus) and coyote (Canis latrans).

Our method produced scale‐integrated RSFs that represented the relative probability of encounter. The predicted spatial distribution of encounters obtained based on this scale‐integrated approach produced distributions that more accurately predicted novel encounters than a naïve approach or any individual scale alone.

Our results highlight the importance of accounting for the conditional nature of habitat selection in estimating the habitat associations of animal encounters as opposed to ‘naïve’ comparisons of encounter locations with general availability. This method has direct relevance for testing hypotheses about the relationship between habitat and social or predator–prey behaviour and generating spatial predictions of encounters. Such spatial predictions may be vital for understanding the distribution of encounters driving disease transmission, predation rates and other population and community‐level processes.
England's statutory biodiversity metric enhances plant, but not bird nor butterfly, biodiversity
Authors: Marshall Cicely A. M. , Wade Kristian , Kendall Isla S. , Porcher Hannah , Poffley Jakob , Bladon Andrew J. , Dicks Lynn V. , Treweek Jo 
Published: June 2024

Abstract

Biodiversity net gain is a policy focus worldwide, acknowledging ongoing losses of biodiversity to development, and a commitment to offsetting any residual impacts on biodiversity elsewhere. At least 37 countries have mandatory offsetting policies, and a further 64 countries enable voluntary offsets. Offsets rely on credible and evidence‐based methods to quantify biodiversity losses and gains.

Following the introduction of the United Kingdom's Environment Act in November 2021, all new developments requiring planning permission in England must demonstrate a biodiversity net gain of at least 10% biodiversity net gain from 2024, calculated using a statutory biodiversity metric framework. The metric uses habitat as a proxy for biodiversity, scoring habitats' intrinsic distinctiveness and current condition.

We carried out a study of the metric's performance across England in terms of outcomes for biodiversity. We used generalized linear mixed models to regress baseline biodiversity units against five long‐established single‐attribute proxies for biodiversity (species richness, individual abundance, number of threatened species, mean species range and mean species range/population change). Data were gathered for species belonging to three commonly used indicator taxa (vascular plants, butterflies and birds) from 24 sites, including all terrestrial broad habitats except urban.

In baseline assessments, metric‐derived biodiversity units correlated with most plant biodiversity variables, but not with any of the bird or butterfly biodiversity variables used in this study. Plant species recorded in habitats with higher baseline biodiversity units had slightly more restricted ranges (slope −16.22 ± 1.52, p < 0.001) on average and had shown stronger past declines (slope −0.02 ± 0.00, p < 0.001) than those in habitats with lower baseline biodiversity units. Each additional baseline biodiversity unit was associated with a 1% increase in plant species richness (p < 0.01).

Synthesis and applications: Using the statutory biodiversity metric to define 10% biodiversity net gain without additional species‐focused conservation management is likely to translate into small gains for plant biodiversity, and negligible gains for birds and butterflies. We make specific recommendations to improve the metric's efficacy in achieving desirable biodiversity outcomes. Our results provide a valuable case study for other countries interested in developing metrics to support biodiversity net gain policies.
Family and career: an analysis across Europe and North America
Authors: Guirola Luis , Hospido Laura , Weber Andrea 
Published: June 2024

AbstractUsing data on 17 countries in Europe and North America, we compare the career trajectories of mothers and fathers and of women and men without children across cohorts, and at different points of their life cycle. There is wide variation across countries in employment and earnings gaps at age 30. At age 50, however, the employment gap between mothers and non‐mothers has closed in most countries. We also observe convergence in employment gaps between mothers and fathers by age 50, but these gaps do not fully close. Motherhood gaps in earnings also close by age 50 between mothers and non‐mothers, particularly among the highly educated. But there is strong persistence in earnings gaps between mothers and fathers even among highly educated parents. The main reasons for the remaining gaps at later stages in the life cycle are part‐time work among women and fatherhood premia as fathers' earnings outperform non‐fathers' over their life cycle.
Examining inequalities: from labour markets to social outcomes in Finland
Authors: Paukkeri Tuuli , Ravaska Terhi , Riihelä Marja 
Published: June 2024

AbstractFinland is known for low income inequality by international comparison. In this paper we provide a long‐run perspective on inequalities in Finland, and show that inequality is higher in the 21st century compared with many previous decades. We discuss the drivers of inequality in more detail, focusing on wages, earnings, employment and education, and also social outcomes such as partner‐finding and family formation in the working‐age population. The collective wage‐setting system is a likely contributor to the relatively low and stable wage and earnings inequality among working indviduals. However, women fare worse in the labour market than men, despite having a higher education level on average. We also find that individuals who are out of work or have low education have a lower probability of finding a partner, indicating that social inequalities are linked with those in the labour market. Finally, we discuss the importance of redistribution as well as changes in tax legislation that have contributed to an increasing concentration of capital income, which has been an important factor in increasing households’ disposable income inequality.
Health status and quality of life before critical illness: Northern Finland Birth Cohort 1966 study
Authors: Niittyvuopio Miikka , Hietanen Siiri , Liisanantti Janne , Spalding Michael , Auvinen Juha , Ala‐Kokko Tero 
Published: June 2024

AbstractBackgroundPrevious findings support the claim intensive care unit (ICU) patients have a higher rate of comorbidities and reduction of health‐ and functional status compared with the normal population.AimIn this prospective observational study, our aim was to determine those health‐related factors at the age of 31 years which were associated with a later critical illness among previously un‐hospitalized individuals by exploring data obtained from the Northern Finland Birth Cohort 1966 (NFBC1966).MethodsNFBC1966 is a Finnish birth cohort, which includes 12,058 live births with expected dates of delivery during 1966. The study was conducted among cohort participants who had not been hospitalized for any reason before the cohort follow‐up visit at the age of 31. The study group included NFBC1966 participants who were admitted to the ICU of the Oulu University Hospital. The control group included participants who were treated for any reason in regular hospital wards. The data considering the participants’ health status and behavior at the age of 31 were collected from the NFBC1966 database. The gathering of ICU and hospitalization data was concluded on December 31, 2016.Results849 NFBC1966 participants met the inclusion criteria: 69 were treated in the ICU (study group) and 780 on regular hospital wards (controls). In the study group, the rate of neurological diseases (26% vs. 16%, 95% CI: −21.8%, −0.2%), malignancy (3% vs. 0.7%, 95% CI: −9.7%, 0.0%), alcohol abuse (4.5% vs. 1%, 95% CI: −11.5%, −0.3%) and smoking (77% vs. 65%, 95% CI: −21.6%, −0.3%) were higher compared with the control group. The patients in the ICU group were also more prone to violent injuries, (17% vs. 7%, 95% CI: −20.2%, −1.9%), practiced less hard physical activity (65% vs. 78%, 95% CI: 2.1%, 25.3%) and had lower maximal muscle strength according to the hand grip test (30 vs. 34 kg, 95% CI: −8.2, 8.6 kg).ConclusionsIn this study examining previously un‐hospitalized patients, the main factors associated with future critical illness were neurological comorbidities, malignancy, alcohol misuse, smoking, low maximum muscle strength, and less frequent physical exercise compared with those with hospitalization not requiring ICU admission.
Precision emergency medicine
Authors: Strehlow Matthew , Alvarez Al'ai , Blomkalns Andra L. , Caretta‐Wyer Holly , Gharahbaghian Laleh , Imler Daniel , Khan Ayesha , Lee Moon , Lobo Viveta , Newberry Jennifer A. , Ribeira Ryan , Sebok‐Syer Stefanie S. , Shen Sam , Gisondi Michael A. 
Published: June 2024

AbstractBackgroundPrecision health is a burgeoning scientific discipline that aims to incorporate individual variability in biological, behavioral, and social factors to develop personalized health solutions. To date, emergency medicine has not deeply engaged in the precision health movement. However, rapid advances in health technology, data science, and medical informatics offer new opportunities for emergency medicine to realize the promises of precision health.MethodsIn this article, we conceptualize precision emergency medicine as an emerging paradigm and identify key drivers of its implementation into current and future clinical practice. We acknowledge important obstacles to the specialty‐wide adoption of precision emergency medicine and offer solutions that conceive a successful path forward.ResultsPrecision emergency medicine is defined as the use of information and technology to deliver acute care effectively, efficiently, and authentically to individual patients and their communities. Key drivers and opportunities include leveraging human data, capitalizing on technology and digital tools, providing deliberate access to care, advancing population health, and reimagining provider education and roles. Overcoming challenges in equity, privacy, and cost is essential for success. We close with a call to action to proactively incorporate precision health into the clinical practice of emergency medicine, the training of future emergency physicians, and the research agenda of the specialty.ConclusionsPrecision emergency medicine leverages new technology and data‐driven artificial intelligence to advance diagnostic testing, individualize patient care plans and therapeutics, and strategically refine the convergence of the health system and the community.
A study on acute expectation effects on affective state and intention after a brief full‐body workout in a student sample
Authors: Hösl Benedikt , Straif Julia , Niedermeier Martin , Kopp Martin 
Published: June 2024

AbstractBrief exercise bouts can have positive effects on the affective state, which in turn could affect the intention for future exercise. Such benefits may be enhanced by manipulating expectations. The aim of this study was to examine whether the affective state after physical activity or the intention for future exercise can be influenced by manipulating expectations. Furthermore, the relationship between affect and intention was investigated. In an online experiment, 121 persons completed either a 10‐minute workout (PA), a workout after manipulation of expectations (PA + EM), or a control intervention (CG) after randomized group allocation. Data on affective state, expectations, and intention were collected before and after the intervention using questionnaires. After intervention, PA groups showed significantly more positive values than CG in several affective parameters, in other affective parameters, only PA + EM differed from CG. Affect was positively associated with intention alongside outcome expectations. No difference was found in intention. Although no significant effects of expectation manipulation on affective state or intention were found, latent effects cannot be ruled out. Further exploration of the importance of word choice in describing physical activity in the context of interventions to increase physical activity is necessary. Here, affect should be considered.
Letter: Over‐the‐scope clips in patients at high risk of rebleeding following upper gastrointestinal tract bleeding—The magic bullet for everyone? Authors'reply
Authors: Song Kai , Yang Daiyu , Xu Hemiao , He Kun , Wang Qiang , Wu Dong 
Published: June 2024

LINKED CONTENTThis article is linked to He et al papers. To view these articles, visithttps://doi.org/10.1111/apt.18093andhttps://doi.org/10.1111/apt.18130
Beads of Alexandria: Non‐invasive analysis of glass from Roman, Late Antique and Islamic Kom el‐Dikka, Egypt
Authors: Then‐Obłuska Joanna , Syta Olga 
Published: July 2024

AbstractWritten sources indicate that Alexandria in Egypt was a leading producer of Roman glass. Furthermore, archaeological finds have provided evidence for the local production of drawn glass and gold‐in‐glass beads, which were distributed throughout the world. In this study, we present an analysis of the chemical composition of more than two hundred glass objects from the Roman (2nd–3rd/4th century ce) and Late Antique (4th/5th–7th century ce) glass bead workshops located at Kom el‐Dikka in Alexandria. This study is based on the results of portable X‐ray fluorescence (pXRF) analyses carried out on raw glass, bead semi‐products, products and waste from both periods. Additionally, the glass chemistry of some Islamic (8th–12th century ce) beads found at the site has been analysed.Despite the limitations of the method, the vast majority of samples exhibited compositions confirming their general dating and Egyptian origin. Remarkably, a single bead was made of high‐alumina glass and appeared to be an import from India, possibly a remnant of the Indo‐Pacific glass bead route that connected Red Sea ports and Europe in Late Antiquity. In addition, we offer a new analytical approach to the method that has potential to enhance the value of pXRF in the analysis of archaeological glass.
Afatinib plus PEM and CBDCA overcome osimertinib resistance in EGFR‐mutated NSCLC with high thrombospondin‐1 expression
Authors: Onda Naomi , Nakamichi Shinji , Hirao Mariko , Matsuda Kuniko , Matsumoto Masaru , Miyanaga Akihiko , Noro Rintaro , Gemma Akihiko , Seike Masahiro 
Published: June 2024

AbstractOsimertinib induces a marked response in non–small‐cell lung cancer (NSCLC) patients harboring epidermal growth factor receptor (EGFR) gene mutations. However, acquired resistance to osimertinib remains an inevitable problem. In this study, we aimed to investigate osimertinib‐resistant mechanisms and evaluate the combination therapy of afatinib and chemotherapy. We established osimertinib‐resistant cell lines (PC‐9‐OR and H1975‐OR) from EGFR‐mutant lung adenocarcinoma cell lines PC‐9 and H1975 by high exposure and stepwise method. Combination therapy of afatinib plus carboplatin (CBDCA) and pemetrexed (PEM) was effective in both parental and osimertinib‐resistant cells. We found that expression of thrombospondin‐1 (TSP‐1) was upregulated in resistant cells using cDNA microarray analysis. We demonstrated that TSP‐1 increases the expression of matrix metalloproteinases through integrin signaling and promotes tumor invasion in both PC‐9‐OR and H1975‐OR, and that epithelial‐to‐mesenchymal transition (EMT) was involved in H1975‐OR. Afatinib plus CBDCA and PEM reversed TSP‐1‐induced invasion ability and EMT changes in resistant cells. In PC‐9‐OR xenograft mouse models (five female Balb/c‐Nude mice in each group), combination therapy strongly inhibited tumor growth compared with afatinib monotherapy (5 mg/kg, orally, five times per week) or CBDCA (75 mg/kg, intraperitoneally, one time per week) + PEM (100 mg/kg, intraperitoneally, one time per week) over a 28‐day period. These results suggest that the combination of afatinib plus CBDCA and PEM, which effectively suppresses TSP‐1 expression, may be a promising option in EGFR‐mutated NSCLC patients after the acquisition of osimertinib resistance.
Severe Allergy as a Chronic Inflammatory Condition From a Systems Biology Perspective
Authors: Delgado Dolset M. I. , Pablo‐Torres C. , Contreras N. , Couto‐Rodríguez A. , Escolar‐Peña A. , Graña‐Castro O. , Izquierdo E. , López‐Rodríguez J. C. , Macías‐Camero A. , Pérez‐Gordo M. , Villaseñor A. , Zubeldia‐Varela E. , Barber D. , Escribese M. M. 
Published: June 2024

ABSTRACTPersistent and unresolved inflammation is a common underlying factor observed in several and seemingly unrelated human diseases, including cardiovascular and neurodegenerative diseases. Particularly, in atopic conditions, acute inflammatory responses such as those triggered by insect venom, food or drug allergies possess also a life‐threatening potential. However, respiratory allergies predominantly exhibit late immune responses associated with chronic inflammation, that can eventually progress into a severe phenotype displaying similar features as those observed in other chronic inflammatory diseases, as is the case of uncontrolled severe asthma. This review aims to explore the different facets and systems involved in chronic allergic inflammation, including processes such as tissue remodelling and immune cell dysregulation, as well as genetic, metabolic and microbiota alterations, which are common to other inflammatory conditions. Our goal here was to deepen on the understanding of an entangled disease as is chronic allergic inflammation and expose potential avenues for the development of better diagnostic and intervention strategies.
HDR syndrome: Large cohort and systematic review
Authors: Rive Le Gouard Nicolas , Lafond‐Rive Valentin , Jonard Laurence , Loundon Natalie , Achard Sophie , Heidet Laurence , Mosnier Isabelle , Lyonnet Stanislas , Brioude Frederic , Serey Gaut Margaux , Marlin Sandrine 
Published: June 2024

AbstractHDR syndrome is a rare disease characterized by hypoparathyroidism, deafness, and renal dysplasia. An autosomal dominant disease caused by heterozygous pathogenic GATA3 variants, the penetrance of each associated condition is variable. Literature reviews have provided some answers, but many questions remain, in particular what the relationship is between genotype and phenotype. The current study examines 28 patients with HDR syndrome combined with an exhaustive review of the literature. Some conditions such as hearing loss are almost always present, while others described as rare initially, do not seem to be so rare after all (genital malformations and basal ganglia calcifications). By modeling pathogenic GATA3 variants found in HDR syndrome, we found that missense variations appear to always be located in the same area (close to the two Zinc Finger domain). We describe new pathogenic GATA3 variants, of which some seem to always be associated with certain conditions. Many audiograms were studied to establish a typical audiometric profile associated with a phenotype in HDR. As mentioned in the literature, hearing function should always be assessed as early as possible and follow up of patients with HDR syndrome should include monitoring of parathyroid function and vesicoureteral reflux in order to prevent complications.