bluuebunny/crossref_metadata_2025_split huggingface dataset:
Determinants of completed railway suicides by psychiatric in-patients: case–control study
Authors: Lukaschek Karoline , Baumert Jens , Krawitz Marion , Erazo Natalia , Förstl Hans , Ladwig Karl-Heinz 
Published: September 2014

BackgroundSuicide prediction during psychiatric in-patient treatment remains an unresolved challenge.AimsTo identify determinants of railway suicides in individuals receiving in-patient psychiatric treatment.MethodThe study population was drawn from patients admitted to six psychiatric hospitals in Germany during a 10-year period (1997–2006). Data from 101 railway suicide cases were compared with a control group of 101 discharged patients matched for age, gender and diagnosis.ResultsPredictors of suicide were change of therapist (OR = 22.86,P= 0.004), suicidal ideation (OR = 7.92,P<0.001), negative or unchanged therapeutic course (OR = 7.73,P<0.001), need of polypharmaceutical treatment (OR = 2.81,P= 0.04) and unemployment (OR = 2.72,P= 0.04). Neither restlessness nor impulsivity predicted in-patient suicide.ConclusionsSuicidal ideation, unfavourable clinical course and the use of multiple psychotropic substances (reflecting the severity of illness) were strong determinants of railway suicides. The most salient finding was the vital impact of a change of therapist. These findings deserve integration into the clinical management of patients with serious mental disease.
Improvement Reserves of Modern Engeneer’s Geometrical and Graphics Training
Authors: Ярошевич  , Yaroshevich O. 
Published: September 2014

The paper is devoted to peculiarities and status of
students’ geometrical and graphic training (GGT) in the context
of educational process’s globalization and informatization. Analysis
is performed from the position of consecutive transition from an
academic subject (engineering graphics) to educational process’s
interactive participants, such as student – teacher – chair. Problems,
positive and negative sides are revealed; their possible solutions are
denoted. The emphasis is on consolidating of high educational
institutions’ graphic disciplines chairs as a determining link of GGT.
The conclusion is made that, under current circumstances, the type
of modern professor is formed, which must possess the knowledge
in informational and communicational technologies’ area, as well as be able to apply it at his professional activity. The need of educational
process providing with a quality study materials, as means
for students’ individual work organization and cognitive abilities
formation is emphasizeds.
Building and Strengthening Infrastructure for Data Exchange: Lessons from the
Beacon Communities
Authors: Torres Gretchen , Swietek Karen , Ubri Petry S. , Singer Rachel , Lowell Kristina , Miller Wilhelmine 
Published: September 2014

Introduction: The Beacon Community Cooperative Agreement Program supports
interventions, including care-delivery innovations, provider performance measurement and
feedback initiatives, and tools for providers and consumers to enhance care. Using a
learning health system framework, we examine the Beacon Communities’ processes in
building and strengthening health IT (HIT) infrastructures, specifically successes and
challenges in sharing patient information to improve clinical care.Background: In 2010,
the Office of the National Coordinator for Health Information Technology (ONC) launched
the three-year program, which provided $250 million to 17 Beacon Communities to invest
in HIT and health information exchange (HIE) infrastructure. Beacon Communities used
this funding to develop and disseminate HIT-enabled quality improvement practices found
effective in particular community and practice environments.Methods: NORC conducted 7
site visits, November 2012– March 2013, selecting Communities to represent diverse
program features. From August–October 2013, NORC held discussions with the remaining 10
Communities. Following each visit or discussion, NORC summarized the information
gathered, including transcripts, team observations, and other documents the Community
provided, to facilitate a within-Community analysis of context and stakeholders,
intervention strategies, enabling factors, and challenges.Results: Although each
Community designed and implemented data-sharing strategies in a unique environment,
similar challenges and enabling factors emerged across the Beacons. From a learning
health system perspective, their strategies to build and strengthen data-sharing
infrastructures address the following crosscutting priorities: promoting technical
advances and innovations by helping providers adapt EHRs for data exchange and
performance measurement with customizable IT and offering technical support to smaller,
independent providers; engaging key stakeholders; and fostering transparent governance
and stewardship of the infrastructure with neutral conveners.Conclusion: While all the
Communities developed or strengthened data-exchange infrastructure, each did this in a
unique environment of existing health care market and legal factors. The Communities,
however, encountered similar challenges and enabling factors. Organizations undertaking
collaborative data sharing, performance measurement and clinical transformation can
learn from the Beacon Communities’ experience.
Detection of HLA-B*58:01 with TaqMan assay and its association with allopurinol-induced sCADR
Authors: Zhang Xinju , Ma Huili , Hu Chunying , Yu Bo , Ma Weizhe , Wu Zhiyuan , Luo Xiaoqun , Zou Hejian , Guan Ming 
Published: September 2014

AbstractTheA new method combining sequence-specific primers (SSP) and TaqMan probe amplification was developed in this study and was used to detect theThe new method successfully identified HLA-B*58:01 in thousands of
Dry ice exposure of plasma samples influences pH and lupus anticoagulant analysis
Authors: Odsæter Ingrid Hov , Lian Ingrid Alsos , Bratberg Kari , Mikkelsen Gustav 
Published: September 2014

AbstractTests for lupus anticoagulant (LA), including silica clotting time (SCT) and diluted Russel’s viper venom time (dRVVT) are used to diagnose antiphospholipid syndrome. Due to sample instability, it is recommended that samples are frozen if analysis is postponed >4 h. Shipping on dry ice is common practice to keep samples frozen during transport. Recent data suggest that exposure to dry ice may affect sample pH and results in subsequent analyses. We aimed to determine the effect of dry ice on pH and LA analysis.Citrated plasma from eight healthy volunteers was allocated to three preanalytical regimes: 1) storage at –20 °C; 2) dry ice exposure followed by storage at –20 °C; or 3) dry ice exposure followed by storage at –80 °C.Samples stored at –20 °C after dry ice exposure had significantly lower median pH (1.2 units, p=0.01) and prolonged clotting time ratios (up to 55% for dRVVT tests, p<0.02) in LA analysis, compared to samples not exposed to dry ice. This resulted in poor test specificity (25%). Similar changes were not observed in samples placed at –80 °C after dry ice exposure.Dry ice may affect sample pH and increase the fraction of false positive LA results. This preanalytical factor should be taken into account by laboratories receiving frozen samples for these tests.
How Science 2.0 will impact on scientific libraries
Authors: Tochtermann Klaus 
Published: September 2014

Abstract
With the event of Social Media, well established principles of
scholarly communication have changed dramatically. For centuries
libraries served as single point of access to scientific
literature. Social Media however brings up new publication forms,
e. g. scientific wikis, new communication channels,
e. g. micro-blogs, or community driven research and publication
envirnoments, e. g. Mendeley or ResearchGate. Based upon our own
experiences within ZBW – Leibniz Information Centre for Economics, we
present how research and development in computer science will help
scientific libraries to manage the necessary change within the next
decade.
Objektklassifikation anhand von RGBD-Daten mithilfe konsonanter kontinuierlicher Belief-Funktionen
Authors: Lietz Mario , Puente León Fernando 
Published: September 2014

Zusammenfassung
Momentane Technologien haben die Aufnahme von 3D-Punktdaten stark
vereinfacht, wodurch es zu einem Entwicklungssprung in der
Objekterkennung gekommen ist. Zur Mustererkennung und bei
Klassifikationsaufgaben wird die Belief-Theorie bereits verwendet;
dabei werden jedoch weitestgehend nur diskrete Räume betrachtet. Die
Erweiterung der Belief-Theorie für den kontinuierlichen Raum eröffnet
neue Möglichkeiten in der Datenfusion. Dazu werden in dieser Arbeit
konsonante mehrdimensionale Belief-Funktionen konstruiert und dazu
passende modellbasierte Merkmalsverfahren entwickelt. Eine Evaluierung
geschieht am Beispiel der Klassifikation von Haushaltsgegenständen.
Effect of Confinement on Creep Behavior of EPS Geofoam
Authors: Birhan Amsalu G. , Negussey Dawit 
Published: September 2014

Abstract
Time-dependent deformation under sustained loading or creep is an important consideration in the long-term performance of expanded polystyrene (EPS) geofoam. The design of EPS geofoam fills is mainly based on limiting working stresses to produce tolerable deformations. Results from unconfined uniaxial creep tests have provided justification for such design criteria. With different types of applications involving submergence and higher surcharge loads, creep deformations under confining pressures have been occurring. A series of creep tests were performed on different densities of EPS geofoam with and without confining pressures. The results showed confining pressures can significantly affect the creep responses of EPS geofoam. Effects of confining pressures on creep deformations were more pronounced at lower densities.
Cooling Characteristics of Water Based Nanofluids With Agitation
Authors: Župan Josip , Landek Darko , Filetin Tomislav 
Published: September 2014

Abstract
A series of quenching experiments was performed according to the ISO 9950, ASTM 6200-01, and ASTM D6482-06 standards. Water based nanofluids with 0.01, 0.1, and 0.2 g/L TiO2 were prepared using a two-step method and ultrasonic homogenization. The nanofluids were tested to see the possibility of their application as high temperature heat transfer fluids. Nanoparticles used in this series of experiments were 50 nm in diameter. All of the cooling curves were recorded and analyzed using the ivf SmartQuench system. The first set of experiments was conducted under still conditions according to the ISO 9950 standard. Pure water and nanofluids were investigated. The addition of nanoparticles showed an effect on the full film phase duration, an increase in the maximum cooling rate, and a change in transition temperature. A second series of quenching experiments was conducted according to ASTM D 6482-06. For this purpose, a quenching bath with agitation was built at the QRC. Three levels of agitation were tested: one according to the standard, 1000 rpm, one below, and one above the specified speed. Experiments with pure water and all three nanofluids were conducted and cooling curves recorded. The cooling curves were analyzed using software ivf SQintegra ver4.0. The effects of agitation and nanoparticles contents on cooling characteristics were compared.
Enhanced Fatigue Performance of a Polymer Nanocomposite under Spectrum Loads
Authors: Manjunatha C. M. , Bojja Ramesh , Jagannathan N. 
Published: September 2014

Abstract
A thermosetting epoxy polymer was modified by incorporating 10 wt. % of silica nanoparticles, which were well dispersed in the polymer. Two different glass-fiber-reinforced plastic (GFRP) composite laminates were prepared to give: (1) a GFRP composite with an unmodified epoxy matrix (GFRP neat), and (2) a GFRP composite with a silica-nanoparticle-modified epoxy matrix (GFRP nano). Fatigue tests were undertaken employing a standard wind-turbine spectrum-load sequence, WISPERX. The fatigue life of the GFRP nanocomposite was about four times longer than that of the GFRP neat composite. This was reflected in (1) the development of matrix cracking, and (2) the rate of degradation of the stiffness of the composite, both being more severe in the GFRP neat composite, compared to the GFRP nanocomposite. The underlying mechanisms for the observed improvement in the spectrum fatigue life of the GFRP nanocomposite are discussed. Further, constant amplitude fatigue tests were conducted at various stress ratios. Using the static and fatigue data, constant life diagrams (CLD) were constructed. The spectrum fatigue life was then predicted following a standard procedure using the CLD. Very good correlation was observed between the predicted and experimental fatigue life for both GFRP neat and GFRP nanocomposites.
SNW1 enables sister chromatid cohesion by mediating the splicing of sororin and APC2 pre‐mRNAs
Authors: van der Lelij Petra , Stocsits Roman R , Ladurner Rene , Petzold Georg , Kreidl Emanuel , Koch Birgit , Schmitz Julia , Neumann Beate , Ellenberg Jan , Peters Jan‐Michael 
Published: September 2014

AbstractAlthough splicing is essential for the expression of most eukaryotic genes, inactivation of splicing factors causes specific defects in mitosis. The molecular cause of this defect is unknown. Here, we show that the spliceosome subunits SNW1 and PRPF8 are essential for sister chromatid cohesion in human cells. A transcriptome‐wide analysis revealed that SNW1 or PRPF8 depletion affects the splicing of specific introns in a subset of pre‐mRNAs, including pre‐mRNAs encoding the cohesion protein sororin and the APC/C subunit APC2. SNW1 depletion causes cohesion defects predominantly by reducing sororin levels, which causes destabilisation of cohesin on DNA. SNW1 depletion also reduces APC/C activity and contributes to cohesion defects indirectly by delaying mitosis and causing “cohesion fatigue”. Simultaneous expression of sororin and APC2 from intron‐less cDNAs restores cohesion in SNW1‐depleted cells. These results indicate that the spliceosome is required for mitosis because it enables expression of genes essential for cohesion. Our transcriptome‐wide identification of retained introns in SNW1‐ and PRPF8‐depleted cells may help to understand the aetiology of diseases associated with splicing defects, such as retinosa pigmentosum and cancer.
Functional genomics identifies a requirement of pre‐mRNA splicing factors for sister chromatid cohesion
Authors: Sundaramoorthy Sriramkumar , Vázquez‐Novelle María Dolores , Lekomtsev Sergey , Howell Michael , Petronczki Mark 
Published: September 2014

AbstractSister chromatid cohesion mediated by the cohesin complex is essential for chromosome segregation during cell division. Using functional genomic screening, we identify a set of 26 pre‐mRNA splicing factors that are required for sister chromatid cohesion in human cells. Loss of spliceosome subunits increases the dissociation rate of cohesin from chromatin and abrogates cohesion after DNA replication, ultimately causing mitotic catastrophe. Depletion of splicing factors causes defective processing of the pre‐mRNA encoding sororin, a factor required for the stable association of cohesin with chromatin, and an associated reduction of sororin protein level. Expression of an intronless version of sororin and depletion of the cohesin release protein WAPL suppress the cohesion defect in cells lacking splicing factors. We propose that spliceosome components contribute to sister chromatid cohesion and mitotic chromosome segregation through splicing of sororin pre‐mRNA. Our results highlight the loss of cohesion as an early cellular consequence of compromised splicing. This may have clinical implications because SF3B1, a splicing factor that we identify to be essential for cohesion, is recurrently mutated in chronic lymphocytic leukaemia.
New Low Temperature Process of CO2 Recovery from Natural Gases
Authors: Imaev Salavat Z. , Bagirov Lev A. , Borisov Vasily E. , Voytenkov Evgeny V. 
Published: September 2014

Abstract
Low-temperature processes seem to be the most promising for the extraction of CO2 from gases with high acid components content. The present paper contains the research results of using supersonic separation technology (3S-separation) for the extraction of CO2 from natural gases. 3S-separation technology is based on separation of selected components of natural gas, effected by gas expansion in a supersonic Laval nozzle, in which a strong gas cooling is achieved due to the conversion of potential energy into kinetic energy. Condensation and separation of the target components are implemented in a cooled flow inside the nozzle.
This paper analyzes the various technological schemes of CO2 extraction. The results of tests of model 3S-separator, confirmed the high efficiency of CO2 separation, are represented. It is proven, that units for CO2 recovery from natural gas, based on low-temperature separation processes in supersonic separators, allow CO2 concentration in processed gas below 2%.
Utility Hydraulic Calculation Model of Herschel-Bulkley Rheological Model for MPD Hydraulics
Authors: Fan H. , Zhou H. , Wang G. , Peng Q. , Wang Y. 
Published: September 2014

Abstract
Hydraulics play an important function in many oil field operations, in the case of drilling, with the implementation and promotion of management pressure drilling technology, the role of accurate hydraulic parameter predictions becomes vital for drilling. This paper describes a utility hydraulic calculation model for Herschel-Bulkley (H-B) rheological model.
Firstly, the explicit equation between the wall shear stress and volumetric flow rate of H-B fluid flow in pipe and annuli were obtained. Then, the accurate numerical solutions of wall shear rate and shear stress both in pipe and annuli were obtained. Secondly, we defined a new generalized flow behavior index and effective diameter for H-B fluid annular flow. The generalized effective diameter accounts for the effects both of annuli geometry and fluid rheology but which is different from that was proposed by Reed & Pilehvari. Moreover, through the effective diameter we link the H-B fluid flow both in pipe and annuli to Newtonian pipe flow. At last, a general expression of generalized Reynolds number was derived from this model in view of generalized flow index is non-constant. Then, a theoretical calculation method was proposed for the generalized flow index of both pipe and annular flow and a uniform pressure drop calculation model was obtained. The predictions of the improved hydraulic model have been compared with an extensive set of experimental data. The comparison of different fluids both in pipe and annulus show very good agreement over the entire range of flow types.
Finally, the utility model has been applied in several wells in Sichuan basin and Tarim basin for monitoring real-time hydraulics while MPD, and there is an excellent match between the model and measured data. Therefore, it can be seen that this utility method can be applied to provide more accurate estimations of hydraulic parameters in drilling engineering.
Using the Results from Automated Petroleum Engineering Calculations to Accelerate Decision Workflows
Authors: Fair Chris , Flores Ricardo , Hakim Bilal , Nande Soumitra 
Published: September 2014

Abstract
With the advent and common usage of high resolution tree gauges, downhole permanent pressure/temperature gauges, and continuous flow measurement, many of the common petroleum engineering calculations and analysis tools for production systems can and have been automated. These include: a) Well Test Analysis, b) Well Productivity, c) Static and Flowing Material Balances and Energy Balances. In addition, the use of rigorous wellbore thermal and phase behavior models allows the two gauges (wellhead and downhole) to be used as a giant differential pressure meter – making it possible to calculate gas rates and water cuts independently of the flow measurements, as well as mid-completion bottomhole pressure (BHP).
The purpose of this paper is to present the basic physics involved in these calculations/analyses, as well as to discuss the implications that these processes will have on instrumentation selection and on engineering work flows. The crux of the argument for these types of automated systems is that it is much easier for an engineer to check the results than to spend his/her entire day just looking for useful information in the database, then analyzing it (or getting someone else to analyze it). Furthermore, being able to see the “big picture” – seeing what skin, perm, productivity and apparent hydrocarbon reservoir volumes are now and how they have changed with time, allows engineers to make quicker, more accurate decisions. The use of automated analysis also reduces bias – the computer doesn't care what the answer is. This paper will also include several case studies for both oil and gas wells.
Enhanced Oil Recovery through Low Salinity Fines-Assisted Waterflooding: Laboratory and Mathematical Modelling
Authors: Hussain F. , Zeinijahromi A. , Bedrikovetsky P. , Badalyan A. , Carageorgos T. , Cinar Y. 
Published: September 2014

Abstract
The paper presents a systematic laboratory study to investigate the underlying physical mechanisms for improved oil recovery as a consequence of low-salinity water injection. Three sister plugs of Berea sandstone were used in the experiments. All three plugs were initially saturated with high salinity water (4 g/L NaCl). Single phase water flow test was performed in the first plug. The salinity of the injected water was decreased gradually (4 g/L to 0 g/L NaCl). In addition to observe the permeability reduction with reducing salinity, the particle concentration was also measured of the effluents at different stages of the experiment. Higher particle concentration was observed during low salinity injection period. The second plug was subjected to primary oil (Soltrol) drainage to the connate water saturation, followed by high salinity (4 g/L NaCl) water injection. After this connate water saturation was restored by a second oil flood. Finally, low salinity (0 g/L NaCl) injection was carried out. For both high and low salinity floods; oil recovery, pressure drop and effluent particle concentration was noted. Numerical modelling was used to interpret the waterflooding data.
Five to ten times decrease in water relative permeability and some decrease in residual oil saturation were observed during the low-salinity waterflood. Treatment of the low-salinity coreflood data by a numerical model reveals the unusual decrease in water relative permeability with increasing water saturation at high water saturations. This observation is explained by the expansion of rock surface exposed to low-salinity water during the increase of water saturation. A reproducibility test was performed on the third sister plug which confirmed the observations of the second sister plug. The proposed laboratory-based mathematical model can be used to design the injected water concentration which is crucial for a low salinity waterflooding project.