bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessment of the Vasodepressor Reflex in Carotid Sinus Syndrome
Authors: Solari Diana , Maggi Roberto , Oddone Daniele , Solano Alberto , Croci Francesco , Donateo Paolo , Wieling Wouter , Brignole Michele 
Published: April 2014

Background—
Assessment of the vasodepressor reflex in carotid sinus syndrome is influenced by the method of execution of the carotid sinus massage and the coexistence of the cardioinhibitory reflex.

Methods and Results—
Carotid sinus massage reproduced spontaneous symptoms in 164 patients in the presence of hypotension or bradycardia (method of symptoms). When an asystolic pause was induced, the vasodepressor reflex was reassessed after suppression of the asystolic reflex by means of 0.02 mg/kg IV atropine. An isolated vasodepressor form was found in 32 (20%) patients, who had lowest systolic blood pressure (SBP) of 65±15 mm Hg. Of these, only 21 (66%) patients had an SBP fall ≥50 mm Hg, which is the universally accepted cut-off value for the diagnosis of the vasodepressor form. Conversely, a lowest SBP value of ≤85 mm Hg (corresponding to the fifth percentile) detected 97% of vasodepressor patients, but was also present in 84% of the 132 patients with an asystolic reflex. These latter patients had both asystole ≥3 s (mean 7.6±2.2 s) and SBP fall to 63±22 mm Hg: in 46 (28%) patients, symptoms persisted after atropine (mixed form), in the remaining 86 (52%) patients, symptoms did not (cardioinhibitory form) persist.

Conclusions—
The current definition of ≥50 mm Hg SBP fall failed to identify one third of patients with isolated vasodepressor form. A cut-off value of symptomatic SBP of ≤85 mm Hg seems more appropriate, but it is unable to identify cardioinhibitory forms. In asystolic forms, atropine testing is able to distinguish a cardioinhibitory form from a mixed form.
Metabolomic Analysis of Pressure-Overloaded and Infarcted Mouse Hearts
Authors: Sansbury Brian E. , DeMartino Angelica M. , Xie Zhengzhi , Brooks Alan C. , Brainard Robert E. , Watson Lewis J. , DeFilippis Andrew P. , Cummins Timothy D. , Harbeson Matthew A. , Brittian Kenneth R. , Prabhu Sumanth D. , Bhatnagar Aruni , Jones Steven P. , Hill Bradford G. 
Published: April 2014

Background—
Cardiac hypertrophy and heart failure are associated with metabolic dysregulation and a state of chronic energy deficiency. Although several disparate changes in individual metabolic pathways have been described, there has been no global assessment of metabolomic changes in hypertrophic and failing hearts in vivo. Hence, we investigated the impact of pressure overload and infarction on myocardial metabolism.

Methods and Results—
Male C57BL/6J mice were subjected to transverse aortic constriction or permanent coronary occlusion (myocardial infarction [MI]). A combination of LC/MS/MS and GC/MS techniques was used to measure 288 metabolites in these hearts. Both transverse aortic constriction and MI were associated with profound changes in myocardial metabolism affecting up to 40% of all metabolites measured. Prominent changes in branched-chain amino acids were observed after 1 week of transverse aortic constriction and 5 days after MI. Changes in branched-chain amino acids after MI were associated with myocardial insulin resistance. Longer duration of transverse aortic constriction and MI led to a decrease in purines, acylcarnitines, fatty acids, and several lysolipid and sphingolipid species but a marked increase in pyrimidines as well as ascorbate, heme, and other indices of oxidative stress. Cardiac remodeling and contractile dysfunction in hypertrophied hearts were associated with large increases in myocardial, but not plasma, levels of the polyamines putrescine and spermidine as well as the collagen breakdown product prolylhydroxyproline.

Conclusions—
These findings reveal extensive metabolic remodeling common to both hypertrophic and failing hearts that are indicative of extracellular matrix remodeling, insulin resistance and perturbations in amino acid, and lipid and nucleotide metabolism.
Rivaroxaban for Stroke Prevention in East Asian Patients From the ROCKET AF Trial
Authors: Wong Ka Sing Lawrence , Hu Dai Yi , Oomman Abraham , Tan Ru-San , Patel Manesh R. , Singer Daniel E. , Breithardt Günter , Mahaffey Kenneth W. , Becker Richard C. , Califf Robert , Fox Keith A.A. , Berkowitz Scott D. , Hacke Werner , Hankey Graeme J. 
Published: April 2014

Background and Purpose—
In Rivaroxaban Once Daily Oral Direct Factor Xa Inhibitor Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET AF) trial, rivaroxaban was noninferior to dose-adjusted warfarin in preventing stroke or systemic embolism among patients with nonvalvular atrial fibrillation at moderate to high stroke risk. Because of differences in patient demographics, epidemiology, and stroke risk management in East Asia, outcomes and relative effects of rivaroxaban versus warfarin were assessed to determine consistency among East Asians versus other ROCKET AF participants.

Methods—
Baseline demographics and interaction of treatment effects of rivaroxaban and warfarin among patients within East Asia and outside were assessed.

Results—

A total of 932 (6.5%) ROCKET AF participants resided in East Asia. At baseline, East Asians had lower weight, creatinine clearance, and prior vitamin K antagonist use; higher prevalence of prior stroke; and less congestive heart failure and prior myocardial infarction than other participants. Despite higher absolute event rates for efficacy and safety outcomes in East Asians, the relative efficacy of rivaroxaban (20 mg once daily; 15 mg once daily for creatinine clearance of 30–49 mL/min) versus warfarin with respect to the primary efficacy end point (stroke/systemic embolism) was consistent among East Asians and non–East Asians (interaction
P
=0.666). Relative event rates for the major or nonmajor clinically relevant bleeding in patients treated with rivaroxaban and warfarin were consistent among East Asians and non–East Asians (interaction
P
=0.867).

Conclusions—
Observed relative efficacy and safety of rivaroxaban versus warfarin were similar among patients within and outside East Asia. Rivaroxaban, 20 mg once daily, is an alternative to warfarin for stroke prevention in East Asians with nonvalvular atrial fibrillation.

Clinical Trial Registration—

URL:
http://www.clinicaltrials.gov
. Unique identifier: NCT00123456.
Dog at My Feet: A Moment of Identity Construction within Dissertation Acknowledgements
Authors: Billany Ruth 
Published: April 2014

Abstract
Human-animal studies (has) is a legitimate and multidisciplinary academic endeavor. In the last three decades, there has been a proliferation of articles revealing multiple ways of knowing about the human-animal relationship. This paper, informed by social psychological theories, turns the mirror upon new researchers as they emerge as professional selves into academia. Post-graduate students engage multiple and sometimes contradicting identities throughout their candidatures. The unit of analysis is the dissertation acknowledgement (da) at both a structural and functional level. The das have recently become objects of serious empirical investigation as linguistic choice promotes a situated academic, cultural, and social identity in a moment of time. This paper examines the generic structure and purpose of 104 das, with a particular focus on the student-writer’s identity with relationship to nonhuman animals in their lives. Fourteen sub-themes are subsumed into thanking, reflecting, and announcing moves. A case is made that the study of das is a potentially fecund research area for a unique moment of identity construction.
Not Coming to Terms: Nonhuman Animals and the Edge of Theory
Authors: Prade Juliane 
Published: April 2014

AbstractIn the emerging field of animal studies, criticism turns to questions of ethics and animal rights by reading representations of nonhuman animals in philosophy and literature. A rhetoric of coming to terms often shapes such readings and points to a lack of satisfactory answers to two questions: why read nonhuman animals, and why now? These questions are crucial to animal studies but can only be answered by understanding this critical approach as an element of the anthropological discourse, fundamental to philosophy. Examining Aristotle’s and Heidegger’s approaches to thinking about the human-animal relation, it seems that the interest in reading how animals are presented in philosophy is not in coming to definitive terms with this relation or in correcting earlier theories. Rather, it appears to lie in reading the concept of the Animal as marking a limit of terminological language, and thus of theory. The Animal marks the point at which philosophy touches on poetry and withdraws. Criticism is concerned with animals now because the concept of “the animals” keeps casting doubt on theoretical conceptions of the Human and of human language.
What Happened to the Internet? Scientific Communities in Three Low-income Areas, 2000-2010
Authors: Shrum Wesley , Palackal Antony , Dzorgbo Dan-Bright , Mbatia Paul , Schafer Mark , Miller Paige 
Published: April 2014

AbstractThis ten year study suggests that the digital divide in connectivity may have largely closed for the scientific community in parts of the world that were previously unconnected. Almost a decade ago Ynalvezet al. (2005) examined the diffusion of information and communication technologies (icts) in the knowledge production sectors of three developing areas, using data collected at the turn of the millennium. We supplement this data set with a similar survey ten years later. Our analysis addresses the extent to which research communities in three low-income areas (Kenya, Ghana, and Kerala) now have access toicts, providing the first longitudinal data on changes in access to computers, email, and the Internet. In contrast to 2000, where the majority of scientists viewed themselves as users of email but with shared and irregular access to computers and the Internet—access to technology has become almost universal, though significant regional differences remain.
The Korean Wave Hallyu in Looking at Escapism in Peruvian Society
Authors: Ko Nusta Carranza , Kim Jeong-Nam , No Song I. , Simoes Ronald Gobbi 
Published: April 2014

Abstract
Overcoming geographic, cultural, and linguistic differences, the second phase of the Korean wave Hallyu made its mark in Latin America. From the results of the field research conducted in two Latin American countries Brazil and Peru during the summer of 2012, this study examines the effects of the second wave of Hallyu on Peruvian society. In doing so, it regards the demographics, education level, and socio-economic status of the Hallyu consumer groups that reflects the situation of inequality and escapism embedded in Peruvian society. The continuous access to a different culture, distinct from that of one’s own reality through a virtual environment of cyberspace may be a reflection of the individual’s own awareness of despair in the reality in which they find themselves, characterized by inequality and a cyclical nature of class differences.
The Textual Legacy of Abū l-Qāsim al-Qušayrī: a Bibliographic Record1
Authors: Nguyen Martin , Chiabotti Francesco 
Published: April 2014

Abstract
The present article compiles and presents the textual legacy of the Sufi scholar Abū l-Qāsim ʿAbd al-Karīm b. Hawāzin al-Qušayrī (d. 465/1072), whose writings are especially significant for the fields of Islamic mysticism and theology. Every title that has been ascribed to Qušayrī is provided with an entry in which all known information is given; the contents are surveyed when possible, previous scholarly research concerning the text is noted, and the record of its publication or survival in manuscript is listed. The titles are organized alphabetically according to their respective English transliterations from the Arabic.
La naissance de l’hagiographie marocaine : le milieu soufi de Fès et le Mustafād d’al-Tamīmī (m. 603/1206)
Authors: Sanseverino Ruggero Vimercati 
Published: April 2014

Résumé
L’édition du manuscrit du Mustafād fī manāqib al-ʿubbād bi-madīnat Fās wa-mā yalīhā min al-bilād (Le renseignement bénéfique au sujet des faits vertueux et prodigieux des dévots de la ville de Fès et de ses environs) de Muḥammad ʿAbd al-Karīm al-Tamīmī (m. 603/1206), ouvrage que l’on croyait perdu, permet de jeter une nouvelle lumière sur les origines de l’hagiographie marocaine, notamment sur les sources dont elle s’est inspirée et sur les circonstances de son émergence. Rédigé peu avant le célèbre Tašawwuf ilā riǧāl al-taṣawwuf, le Mustafād constitue en effet le premier ouvrage hagiographique du Maroc et ce document significatif est encore assez mal connu dans la recherche occidentale sur l’histoire religieuse du Maghreb.
Muḍṭariban maǧnūnan: A Case of Phraseology and Evolving Motifs of Literary and Medical Love-Sickness in the Tale of Salāmān and Absāl
Authors: Shalev Donna 
Published: April 2014

Abstract
The Tale of Salāmān and Absāl presented as a translation from Greek, attributed in the text’s opening lines to Ḥunayn b. Isḥāq, is saturated with references from a wide-ranging variety of sources with an array of religious, cultural and textual orientations; these, as well as its generic affiliations, ideological leanings, location on the spiritual-metaphysical spectrum and Vorlagen have been studied by many. In this paper, I focus on the wording and literary forms of the text, some of which have been glossed over in the rendition of Henry Corbin, by which this text is often known. My point of departure is a collocation which draws on motifs and phraseology from popular sources, the canons of poetry and poetry in prose (including belles lettres elements in the Qurʾān), as well as terminology in medical literature in Arabic and Greek traditions. Through an analysis of phrasing drawing on philological methods of Blachère, Von Grunebaum, Arazi and others, a contextualization of this Tale (which is not covered in research on “profane love theory” e.g. by Lois Giffen) may lead to a reading of this Hermetic text within a repertoire of “romantic” commonplaces and innovations of expression.
Australasian endemic no more: four new species of Miropotes Nixon (Hymenoptera, Braconidae, Microgastrinae), with the first record from the Oriental region
Authors: Fernández-Triana J. , van Achterberg C. , Whitfield J.B. 
Published: April 2014

Four new species of Miropotes Nixon (Hymenoptera, Braconidae, Microgastrinae) are described: Miropotes orientalis Fernández-Triana & van Achterberg, from Thailand and Vietnam, and three species from Australia, M. austini, M. neglectus, and M. lordhowensis (all authored by Fernández-Triana and Whitfield). A key to all known 14 species of the genus is provided, as well as brief, software-generated descriptions (Lucid 3.5.4). Miropotes is distributed mostly within the Australasian region, although it is here reported for the first time for the Oriental region. The relationships with other genera of Microgastrinae are briefly discussed.
Historical Issues between Korea and Japan and Judicial Activism: Focus on the Recent Supreme Court Decision on Japanese Forced Labor
Authors: Lee Seokwoo , Cho Youngkwan 
Published: April 2014

Abstract
The Supreme Court decision regarding “Compensation for Forced Labor” concerns the victims of forced labor who were employed by Japanese munitions companies for the production of weapons during the colonial era. The victims filed a damage suit against these companies for unlawful acts and for the payment of unpaid wages, for which the Supreme Court upheld their right to compensation and payment of wages. This article describes the progress leading up to these decisions, discusses their significance, and evaluates the implications of judicial activism in these issues that concern Korea’s colonial past.
Is steel wire closure of sternotomy better than polyester suture closure?
Authors: Malhotra Amber , Garg Pankaj , Bishnoi Arvind Kumar , Pendro Varun , Sharma Pranav , Upadhyay Madhav , Gandhi Sanjay 
Published: April 2014

Introduction Median sternotomy is the preferred approach for open heart surgeries. The sternotomy incision is predominantly closed with either steel wire or polyester suture. The type of material used is primarily based on the surgeon’s choice, and both materials achieve a good result. No prospective clinical study has been undertaken to evaluate differences in the incidence of wound infection and the degree of pain associated with both techniques. Patients and methods Our randomized controlled double-blind study included 200 adults undergoing single-valve replacement. The technique of surgery, apart from the material used for sternal closure, was the same in both groups. Postoperatively, patients were analyzed for wound infection and wound pain based on the ASEPSIS score and Numeric Pain Rating Score, respectively. Results The polyester suture group had a significantly higher mean ASEPSIS score, indicating a higher incidence of wound infection, and more late wound complications. The polyester suture group also had a significantly higher mean pain score. The steel wire group had significantly higher mediastinal drain output in the first 48 h after surgery. Conclusion The use of polyester suture for sternal closure in adult patients results in increased wound infection, wound pain, and late wound complications, but lower mediastinal drain output.
Evaluation of diagnostic utility of multidetector computed tomography and magnetic resonance imaging in blunt pancreatic trauma: a prospective study
Authors: Panda Ananya , Kumar Atin , Gamanagatti Shivanand , Bhalla Ashu Seith , Sharma Raju , Kumar Subodh , Mishra Biplab 
Published: April 2014

Background Blunt pancreatic trauma is an uncommon injury with high morbidity and mortality. Retrospective analyses of computed tomography (CT) performance report CT to have variable sensitivity in diagnosing pancreatic injury. Both a prospective analysis of multidetector CT (MDCT) performance and diagnostic utility of magnetic resonance imaging (MRI) in acute blunt pancreatic injury remain unexplored. Purpose To prospectively evaluate the utility of MDCT with MRI correlation in patients with blunt pancreatic trauma using intraoperative findings as the gold standard for analysis. Material and Methods The contrast-enhanced CT (CECT) scans of patients admitted with blunt abdominal trauma were prospectively evaluated for CT signs of pancreatic injury. Patients detected to have pancreatic injury on CT were assigned a CT grade of injury according to American Association for Surgery of Trauma classification. MRI was performed in patients not undergoing immediate laparotomy and MRI grade independent of CT grade was assigned. Surgical grade was taken as gold standard and accuracy of CT and MRI for grading pancreatic injury and pancreatic ductal injury (PDI) was calculated. A quantitative and qualitative comparison of MRI was also done with CT to determine the performance of MRI in acute pancreatic injury. Results Thirty out of 1198 patients with blunt trauma abdomen were detected to have pancreatic injury on CT, which was surgically confirmed in 24 patients. Seventeen underwent MRI and surgical correlation was available in 14 patients. CT and MRI correctly identified the grade of pancreatic injury in 91.7% (22/24) and 92.86% (13/14) patients, respectively. Both CT and MRI correctly identified PDI in 18/19 and 11/12 patients, respectively, with good inter-modality agreement of 88.9% (kappa value of 0.78). MRI also qualitatively added to the information provided by CT and increased diagnostic confidence in 58.8% of patients. Conclusion MDCT performs well in grading pancreatic injury and evaluating pancreatic ductal injury. MRI is useful in evaluation of acute pancreatic trauma as it can increase diagnostic confidence and provide more qualitative information regarding the extent of injury.
Association between interleukin 10 gene polymorphisms and risk of type 2 diabetes mellitus in a Chinese population
Authors: Bai Hua , Jing Danqing , Guo Aitao , Yin Shinan 
Published: April 2014

Objective To investigate the relationship between the interleukin 10 ( IL10) gene single nucleotide polymorphisms (SNP) −1082 G/A (rs1800896), −819 T/C (rs1800871) and −592 A/C (rs1800872) and risk of type 2 diabetes mellitus in a Chinese population. Methods This case–control study recruited patients with type 2 diabetes mellitus and healthy control subjects. Genotyping of the −1082 G/A (rs1800896), −819 T/C (rs1800871) and −592 A/C (rs1800872) SNPs was conducted and genotype frequencies were compared between the two groups. Results The study recruited 364 patients with type 2 diabetes mellitus and 677 healthy controls. Patients carrying the −1082 GG genotype had a significantly increased risk of type 2 diabetes mellitus (adjusted odds ratio [OR] 1.57, 95% confidence interval [CI] 1.03, 2.68), as did those patients carrying the −592 AA genotype (adjusted OR 1.63, 95% CI 1.06, 2.53). Subjects carrying both the −1082 GA + GG and −592 AC + AA genotypes had a significantly increased risk of type 2 diabetes mellitus (adjusted OR 2.03, 95% CI 1.24, 3.15). Conclusions The SNPs −1082G/A and −592 A/C increased the risk for type 2 diabetes mellitus, and could be potential targets for screening for the early detection of the risk of type 2 diabetes mellitus.
Age-related diagnostic utility of rheumatoid factor, anticyclic citrullinated peptide and antikeratin antibodies in Chinese patients with rheumatoid arthritis
Authors: Lin Jinpiao , Liu Can , Yang Bin , Ou Qishui 
Published: April 2014

Objectives Retrospective study to evaluate the diagnostic utility of rheumatoid factor (RF), anticyclic citrullinated peptide antibodies (ACPA) and antikeratin antibodies (AKA) in a broad age range of patients with rheumatoid arthritis (RA). Methods Clinical and serological data from patients with RA were collected and analysed. Patients were stratified according to age (<16 years [juvenile idiopathic arthritis; JIA], 16–40 years; 41–60 years and >60 years) and sex. Results The study included 3725 patients. There were no significant sex-related differences in rates of RF, ACPA or AKA positivity. RF, ACPA and AKA positivity were significantly less common in patients aged <16 years than those aged ≥16 years. There were no other significant differences between age groups. Conclusions RF, ACPA and AKA have better diagnostic value for RA in adult patients than in patients with JIA. A combination of RF, ACPA and AKA serological testing may be a useful diagnostic tool for RA in Chinese adults.