bluuebunny/crossref_metadata_2025_split huggingface dataset:
Label‐Free Cell‐Based Dynamic Mass Redistribution Assays
Authors: Gitschier Hannah J. , Bergeron Audrey B. , Randle David H. 
Published: March 2014

AbstractLabel‐free cell‐based assays offer a powerful approach to drug discovery and compound profiling for endogenously expressed receptors in a variety of cell types, including primary and stem cells. Dynamic mass redistribution (DMR) responses in whole cells following receptor stimulation provide phenotypic activity profiles that are readily amenable to evaluation of compound pharmacology. Protocols are provided in this unit to obtain DMR response profiles in adherent and suspension cells, and then to use known tool compounds to delineate the biology of the underlying signaling pathways from the information‐rich kinetic traces that are recorded. Curr. Protoc. Chem. Biol. 6:39‐51 © 2014 by John Wiley & Sons, Inc.
White Polymer Light‐Emitting Devices for Solid‐State Lighting: Materials, Devices, and Recent Progress
Authors: Ying Lei , Ho Cheuk‐Lam , Wu Hongbin , Cao Yong , Wong Wai‐Yeung 
Published: March 2014

White polymer light‐emitting devices (WPLEDs) have become a field of immense interest in both scientific and industrial communities. They have unique advantages such as low cost, light weight, ease of device fabrication, and large area manufacturing. Applications of WPLEDs for solid‐state lighting are of special interest because about 20% of the generated electricity on the earth is consumed by lighting. To date, incandescent light bulbs (with a typical power efficiency of 12–17 lm W−1) and fluorescent lamps (about 40–70 lm W−1) are the most widely used lighting sources. However, incandescent light bulbs convert 90% of their consumed power into heat while fluorescent lamps contain a small but significant amount of toxic mercury in the tube, which complicates an environmentally friendly disposal. Remarkably, the device performances of WPLEDs have recently been demonstrated to be as efficient as those of fluorescent lamps.Here, we summarize the recent advances in WPLEDs with special attention paid to the design of novel luminescent dopants and device structures. Such advancements minimize the gap (for both efficiency and stability) from other lighting sources such as fluorescent lamps, light‐emitting diodes based on inorganic semiconductors, and vacuum‐deposited small‐molecular devices, thus rendering WPLEDs equally competitive as these counterparts currently in use for illumination purposes.
Novel thermosensitive hydrogel composites based on poly(d,l‐lactide‐co‐glycolide) nanoparticles embedded in poly(n‐isopropyl acrylamide) with sustained drug‐release behavior
Authors: Baghaei Bahareh , Jafari Seyed Hassan , Khonakdar Hossein Ali , Wagenknecht Udo , Heinrich Gert 
Published: March 2014

ABSTRACTTo reach sustained drug release, a new composite drug‐delivery system consisting of poly(d,l‐lactide‐co‐glycolide) (PLGA) nanoparticles (NPs) embedded in thermosensitive poly(N‐isopropyl acrylamide) (PNIPAAm) hydrogels was developed. The PNIPAAm hydrogels were synthesized by free‐radical polymerization and were crosslinked with poly(ethylene glycol) diacrylate, and the PLGA NPs were prepared by a water‐in‐oil‐in‐water double‐emulsion solvent‐evaporation method. The release behavior of the composite hydrogels loaded with albumin–fluorescein isothiocyanate conjugate was studied and compared with that of the drug‐loaded neat hydrogel and PLGA NPs. The results indicate that we could best control the release rate of the drug by loading it to the PLGA NPs and then embedding the whole system in the PNIPAAm hydrogels. The developed composite hydrogel systems showed near zero‐order drug‐release kinetics along with a reduction or omission of initial burst release. The differential scanning calorimetry results reveal that the lower critical solution temperature of the developed composite systems remained almost unchanged (<1°C increase only). Such a characteristic indicated that the thermosensitivity of the PNIPAAm hydrogel was not distinctively affected by the addition of PLGA NPs. In conclusion, an approach was demonstrated for the successful preparation of a new hybrid hydrogel system having improved drug‐release behavior with retained thermosensitivity. The developed systems have enormous potential for many biotechnological applications. © 2014 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2014, 131, 40625.
Ground‐penetrating Radar and Geological Study of the Kudruküla Stone Age Archaeological Site, Northeast Estonia
Authors: Tšugai Alina , Plado Jüri , Jõeleht Argo , Kriiska Aivar , Mustasaar Mario , Raig Hanna , Risberg Jan , Rosentau Alar 
Published: March 2014

ABSTRACTA combined ground‐penetrating radar (GPR), drilling and diatom survey was carried out in order to characterize formation of the Kudruküla Stone Age Comb Ware archaeological site, northeast Estonia. A few decades ago a cultural layer was discovered, located within fine‐grained sands of the right bank of the Kudruküla Stream an altitude of 1.25–1.60 m above sea level. The layer is 15–35 cm thick and composed of poorly sorted sand of intensive reddish colour with abundant arte‐ and ecofacts, human bones, burned hearthstones and charcoal pieces. Artefacts, in particular pottery, are well preserved and frequently present as large pieces. The Kudruküla site holds an exceptional position among other Stone Age coastal settlements in that it is not located directly on top of beach ridges, but is buried under ~3 m of sand. When the Kudruküla settlement existed the level of the Litorina Sea was ~6 m above present sea level, which is ~4.5 m above the present location of the cultural layer. The current research is used to describe the geological structure of the area to provide a perspective on the history of the cultural material, and reveals that the cultural material is not restricted to one layer/lens only because it is irregularly and widely distributed within the sands of Kudruküla. The GPR and diatom analyses show that the Kudruküla cultural material is redeposited, because it occurs within an ancient point‐bar succession of a (Narva) river meander. Originally, the dwelling site had been located on top of the Narva‐Jõesuu sandy coastal ridges, which subsequently suffered erosion and the sand resedimented at the Kudruküla location. Good preservation of the cultural items shows that, after redeposition, they were buried fast, probably within a year. The present Kudruküla stream has cut into the floodplain of the ancient (Narva) river to expose the redeposited layer/lens. Copyright © 2014 John Wiley & Sons, Ltd.
Roswitha Dubach, Verhütungspolitik. Sterilisation im Spannungsfeld von Psychiatrie, Gesellschaft und individuellen Interessen in Zürich (1890–1970)
Authors: Schmuhl Hans‐Walter 
Published: March 2014

AbstractZürich: Chronos Verlag 2013. 351 S., br., ill., € 39,50. ISBN 978‐3‐0340‐1134‐1.
ChemInform Abstract: Hierarchical Synthesis of Mo—Sn Oxide Cage‐Bell Hybrid Structures with Superior Lithium Storage.
Authors: Guo Hong , Liu Lixiang , Li Tingting , Chen Weiwei , Wang Yapeng , Wang Wei 
Published: March 2014

AbstractMoO3‐SnO2@C oxide cage‐bell hybrid nanoparticle aggregates are prepared by a facile Ostwald ripening via solvothermal alcoholysis of SnCl2 and (NH4)6Mo7O24, and sucrose in a mixture of EtOH and glycerol (180 °C, 6‐48 h) followed by drying (60 °C, 12 h) and thermal oxidation (400 °C, 2 h).
ChemInform Abstract: Ordered Mesoporous Carbon‐MoO2 Nanocomposite as High Performance Anode Material in Lithium Ion Batteries.
Authors: Zhou Yuanyuan , Lee Ilbok , Lee Chul Wee , Park Han Soo , Son Hyungbin , Yoon Songhun 
Published: March 2014

AbstractOrdered mesoporous carbon—MoO2 nanocomposites are synthesized based on tri‐constituent co‐assembly using MoCl5, resols, and a commercial tri‐block copolymer F127.
ChemInform Abstract: Porous Perovskite CaMnO3 as an Electrocatalyst for Rechargeable Li—O2 Batteries.
Authors: Han Xiaopeng , Hu Yuxiang , Yang Jingang , Cheng Fangyi , Chen Jun 
Published: March 2014

AbstractNanoporous CaMnO3 nanoparticles are prepared by a sol—gel method from aqueous mixtures of Ca(NO3)2, Mn(NO3)2, citric acid, and ethylene glycol followed by heating the obtained gel at 400 °C for 2 h and at 900 °C for 3 h in air.
ChemInform Abstract: A Novel Aluminoborate Open‐Framework [In(dien)2] [Al2B7O16H2] with Large Chiral Cavities Templated by Chiral Main Group Metal Complexes.
Authors: Cheng Lin , Yang Guo‐Yu 
Published: March 2014

AbstractThe title compound (dien: diethylenetriamine) is prepared by solvothermal reaction of Al(O‐iPr)3, H3BO3, and In(O‐iPr)3 in a 1:1:6 solution of dien, H2O, and Py (autoclave, 180 °C, 7 d; 32% yield).
ChemInform Abstract: A Novel Nonanuclear Hafnium Oxide—Hydroxide—Sulfate Cluster Crystallized from Aqueous Solution.
Authors: Kalaji A. , Soderholm L. 
Published: March 2014

AbstractSingle crystals of (NH4)14 [Hf9O8(OH)6(SO4)14] ·nH2O (n ≅ 12.5) are grown by heating an aqueous solution of HfOCl2, (NH4)2SO4, and H2SO4 (pH 0.93, sealed glass vial, 80 °C, 10 d; 54% yield).
ChemInform Abstract: Efficient Cyclization of Tertiary Amines and Alkenes Promoted by KOt‐Bu—DMF.
Authors: Chen Yan‐yan , Zhang Xue‐jing , Yuan Hui‐min , Wei Wen‐tao , Yan Ming 
Published: March 2014

AbstractThe 6‐endo‐cyclization of substrates (VI) and (VIII) gives rise to corresponding tetrahydroquinoline derivatives, whilst the reaction of substrate (XI) leads to indoline (XII) as a result of a 5‐exo‐cyclization.
ChemInform Abstract: Stereospecific Synthesis of a Twinned Alanine Ester.
Authors: Chin Jik , Kwon Soon Ho , Moozeh Kimia , So Soon Mog , Lough Alan J. , Kim B. Moon 
Published: March 2014

AbstractThe reaction between enantiopure diamine (I) and methyl pyruvate (II) gives the diaza‐Cope rearrangement product (III) in good yield and with excellent stereoselectivity.
ChemInform Abstract: Ligand‐Free PdCl2‐Catalyzed Heck Reaction of Arylboronic Acids and Olefins under Reusable TBAB/H2O Conditions.
Authors: Tang Bo‐Xiao , Fang Xiao‐Niu , Kuang Ren‐Yun , Hu Rong‐Hua , Wang Ji‐Wei , Li Ping , Li Xiao‐hang 
Published: March 2014

AbstractThe aqueous solution containing the catalytic system can be recycled and reused with only moderate loss of activity.
ChemInform Abstract: Regioselective Control by a Catalyst Switch in Palladium‐Catalyzed Benzylallylation of Arylethylidene Malononitriles.
Authors: Zhang Xuan , Yu Xiaoqiang , Feng Xiujuan , Liu Hesong , He Ren , Yamamoto Yoshinori , Bao Ming 
Published: March 2014

AbstractThe regioselectivity of benzylallylation reactions of substrates (I) and (V) is completely overturned with Pd(PPh3)4 used as catalyst instead of Pd‐nanoparticles, generated in situ from Pd2(dba)3 and Bu4NBr.
ChemInform Abstract: Arylation of Diazoesters by a Transient N—H Insertion Organocascade.
Authors: Auvil Tyler J. , So Sonia S. , Mattson Anita E. 
Published: March 2014

AbstractA unique urea‐catalyzed transient N‐H insertion organocascade gives rise to double arylation of nitrodiazoesters (I) and (V), enabling the preparation of a large family of unsymmetric α,α‐diaryl esters.
ChemInform Abstract: Synthesis of 1,5‐Disubstituted (E)‐Pent‐2‐en‐4‐yn‐1‐ones.
Authors: Golovanov A. A. , Latypova D. R. , Bekin V. V. , Pisareva V. S. , Vologzhanina A. V. , Dokichev V. A. 
Published: March 2014

Abstract16 Title compounds of type (III) are prepared.
ChemInform Abstract: Syntheses of Spiro[cyclopent[3]ene‐1,3′‐indoles]s and Tetrahydrocyclohepta[b]indoles from 2,3‐Disubstituted Indoles Through Sigmatropic Rearrangement.
Authors: Chakraborty Amrita , Goswami Koushik , Adiyala Akhila , Sinha Surajit 
Published: March 2014

AbstractPd‐Catalyzed reaction of o‐alkynylanilines (I) and (V) with 3,4‐dichloro‐1‐butane (II) provides 3‐(chlorobutenyl) substituted indoles (III) and (VI) in good yields.
ChemInform Abstract: The Rearrangement of tert‐Butylperoxides for the Construction of Polysubstituted Furans.
Authors: Zheng Xiaojian , Lu Shenglin , Li Zhiping 
Published: March 2014

AbstractThe TfOH‐catalyzed rearrangement of tert‐butyl peroxides of type (I) is developed to construct 2,3‐disubstituted furans.
ChemInform Abstract: Highly Diastereo‐ and Enantioselective [3 + 2] Annulation of Isatin‐Derived Morita—Baylis—Hillman Carbonates with Trifluoropyruvate Catalyzed by Tertiary Amines.
Authors: Zhong Neng‐Jun , Wei Feng , Xuan Qing‐Qing , Liu Li , Wang Dong , Chen Yong‐Jun 
Published: March 2014

AbstractThe 3‐oxa‐spirooxindole products (III) are obtained in good to excellent yields with excellent diastereo‐ and enantioselectivities using a β‐isocinchonine‐derived organocatalyst.
ChemInform Abstract: Copper(II)‐Catalyzed Sequential C,N‐Difunctionalization of 1,4‐Naphthoquinone for the Synthesis of Benzo[f]indole‐4,9‐diones under Base‐Free Condition.
Authors: Sun Jin‐Wei , Wang Xiang‐Shan , Liu Yun 
Published: March 2014

AbstractThe title reaction proceeds for a broad substrate scope with high atom economy and can be performed on gram scale.
ChemInform Abstract: I2‐Mediated Oxidative C—O Bond Formation for the Synthesis of 1,3,4‐Oxadiazoles from Aldehydes and Hydrazides.
Authors: Yu Wenquan , Huang Gang , Zhang Yueteng , Liu Hongxu , Dong Lihong , Yu Xuejun , Li Yujiang , Chang Junbiao 
Published: March 2014

AbstractCoupling of aldehydes and hydrazides followed by I2‐mediated cyclization offers a simple, convenient, and environmentally friendly method to prepare symmetrically and asymmetrically substituted oxadiazoles.
ChemInform Abstract: Palladium‐Catalyzed Intermolecular Aerobic Oxidative Cyclization of 2‐Ethynylanilines with Isocyanides: Regioselective Synthesis of 4‐Halo‐2‐aminoquinolines.
Authors: Liu Bifu , Gao Hanling , Yu Yue , Wu Wanqing , Jiang Huanfeng 
Published: March 2014

AbstractThe title reaction provides a new method to prepare a wide range of 4‐halo‐2‐aminoquinolines.
ChemInform Abstract: Enantioselective Intermolecular [2 + 2] Photocycloadditions of Isoquinolone Mediated by a Chiral Hydrogen‐Bonding Template.
Authors: Coote Susannah C. , Bach Thorsten 
Published: March 2014

AbstractFunctionalized fused cyclobutane products are obtained effectively at low temperature in the presence of a chiral hydrogen‐bonding template with excellent regio‐, diastereo‐ and enantioselectivity.
ChemInform Abstract: Palladium‐Catalyzed Synthesis of 2‐Aminobenzoxazinones by Aerobic Oxidative Coupling of Anthranilic Acids and Isocyanides.
Authors: Vlaar Tjoestil , Orru Romano V. A. , Maes Bert U. W. , Ruijter Eelco 
Published: March 2014

AbstractThe presented scalable reaction does not work for anthranilic acids bearing NO2, I, OH, or COOH substituents.
ChemInform Abstract: Synthesis, Characterization and in vitro Biological Evaluation of Some Novel 1,3,5‐Triazine—Schiff Base Conjugates as Potential Antimycobacterial Agents.
Authors: Avupati Vasudeva Rao , Yejella Rajendra Prasad , Parala Venkateswara Rao , Killari Kishore Naidu , Papasani Venkata Madhava Reddy , Cheepurupalli Prasad , Gavalapu Venkateswara Rao , Boddeda Bhavani 
Published: March 2014

AbstractCompounds (IIIb), (IIIc), and (IIIh) are found to exhibit significant antimycobacterial activity when compared to antitubercular drugs such as ethambutol, pyrazinamide, and streptomycin.
ChemInform Abstract: Systematic Study for the Stereochemistry of the Atherton—Todd Reaction.
Authors: Xiong Biquan , Zhou Yongbo , Zhao Changqiu , Goto Midori , Yin Shuang‐Feng , Han Li‐Biao 
Published: March 2014

AbstractThe stereochemistry of H‐phosphinates with different nucleophiles (amines, alcohols, phenols, and mercaptanes) under Atherton—Todd reaction conditions is investigated.
ChemInform Abstract: Total Synthesis of (+)‐Clavilactone A (IV) and (‐)‐Clavilactone B (III) by Ring‐Opening/Ring‐Closing Metathesis.
Authors: Takao Ken‐ichi , Nanamiya Ryuki , Fukushima Yuuki , Namba Ayumi , Yoshida Keisuke , Tadano Kin‐ichi 
Published: March 2014

AbstractThe key step of this synthesis is the one‐pot transformation of the strained cyclobutenecarboxylate (I) into γ‐butenolide (II) via ring‐opening/ring‐closing metathesis.
Discrimination of Soils and Assessment of Soil Fertility Using Information from an Ion Selective Electrodes Array and Artificial Neural Networks
Authors: Mimendia Aitor , Gutiérrez Juan M. , Alcañiz Josep M. , del Valle Manel 
Published: March 2014

AbstractMultichannel sensor measurements combined with advanced treatment is the departure point for a new concept in sensorics, the electronic tongue. Our setup worked with an array of 20 ion selective electrodes plus an artificial neural network used as a pattern recognition method applied to soil analysis. With this design, we got a versatile tool which was able to perform qualitative and quantitative determinations. As first application, the qualitative discrimination between six distinct soil types based on their extractable components was attempted. The procedure was simplified to a single extraction step before measurements. Water, a BaCl2 saline solution and an acetic acid extract were evaluated as extracting agents. The best performance was reached with the acetic acid extraction method with a correct classification rate and sensitivity both of 94%, and a specificity of 100%. In addition, a quantitative determination of several physicochemical properties of agricultural interest, such as organic carbon content and selected cations (like K+ or Mg2+) and anions (like NO3− or Cl−) was also demonstrated, showing satisfactory agreement with the reference methods.
An improved method for determining the phosphorus content in vegetable oils
Authors: Chen Bin , Xiao Xia , Li Rong , Zhao Wanli , Yang Kaidi , Chen Guoliang , Ma Xiaoxun 
Published: March 2014

During pretreatment process for oil sample, charring and ashing processes of oil in AOCS Official Method Ca 12‐55 were improved. Oil was pretreated with concentrated sulfuric acid and potassium hydroxide instead of zinc oxide. As a result, soluble phosphate was obtained in a short time, the subsequent steps were also simplified. Firstly, phosphorus contents were measured, then the equivalent phosphatide contents in oil samples were calculated, RSD (relative SD) was only 1.03%. According to the spiking experiments at low, middle and high concentration levels, recoveries were between 97.03 and 100.99%, RSD were all less than 1.57% (n = 5). The method was applied for determining the equivalent phosphatide content of different types of oils. Compared with AOCS Official Method Ca 12‐55, the improved method can provide a more effective means for detecting and analyzing the phosphorus or the equivalent phosphatide content in vegetable oils.Practical applications: In theory, the applicable scope of the improved method should be consistent with that of AOCS Official Method Ca 12‐55, that is, the method is also suitable for detecting phosphorus or the equivalent phosphatide content in crude, degummed and refined vegetable oils. However, the promotion of the method should be based on more experimental data from various vegetable oils.
Estimating and Forecasting APARCH‐Skew‐t Model by Wavelet Support Vector Machines
Authors: Li Yushu 
Published: March 2014

ABSTRACTThis paper concentrates on comparing estimation and forecasting ability of quasi‐maximum likelihood (QML) and support vector machines (SVM) for financial data. The financial series are fitted into a family of asymmetric power ARCH (APARCH) models. As the skewness and kurtosis are common characteristics of the financial series, a skew‐t distributed innovation is assumed to model the fat tail and asymmetry. Prior research indicates that the QML estimator for the APARCH model is inefficient when the data distribution shows departure from normality, so the current paper utilizes the semi‐parametric‐based SVM method and shows that it is more efficient than the QML under the skewed Student's‐t distributed error. As the SVM is a kernel‐based technique, we further investigate its performance by applying separately a Gaussian kernel and a wavelet kernel. The results suggest that the SVM‐based method generally performs better than QML for both in‐sample and out‐of‐sample data. The outcomes also highlight the fact that the wavelet kernel outperforms the Gaussian kernel with lower forecasting error, better generation capability and more computation efficiency. Copyright © 2014 John Wiley & Sons, Ltd.
Volatility Forecasting via MIDAS, HAR and their Combination: An Empirical Comparative Study for IBOVESPA
Authors: Santos Douglas G. , Ziegelmann Flavio A. 
Published: March 2014

ABSTRACTIn this paper we compare several multi‐period volatility forecasting models, specifically from MIDAS and HAR families. We perform our comparisons in terms of out‐of‐sample volatility forecasting accuracy. We also consider combinations of the models' forecasts. Using intra‐daily returns of the BOVESPA index, we calculate volatility measures such as realized variance, realized power variation and realized bipower variation to be used as regressors in both models. Further, we use a nonparametric procedure for separately measuring the continuous sample path variation and the discontinuous jump part of the quadratic variation process. Thus MIDAS and HAR specifications with the continuous sample path and jump variability measures as separate regressors are estimated. Our results in terms of mean squared error suggest that regressors involving volatility measures which are robust to jumps (i.e. realized bipower variation and realized power variation) are better at forecasting future volatility. However, we find that, in general, the forecasts based on these regressors are not statistically different from those based on realized variance (the benchmark regressor). Moreover, we find that, in general, the relative forecasting performances of the three approaches (i.e. MIDAS, HAR and forecast combinations) are statistically equivalent. Copyright © 2014 John Wiley & Sons, Ltd.
A novel high pressure‐high temperature experimental apparatus to study sequestration of CO2‐SO2 mixtures in geological formations
Authors: García Susana , Liu Qi , Maroto‐Valer M. Mercedes 
Published: March 2014

AbstractA novel experimental set‐up to investigate the sequestration of non‐pure carbon dioxide (CO2) streams in geological formations through mineral trapping is discussed. The system includes a gas manifold system, a gas booster, a fluid reservoir, a high pressure‐high temperature reactor, and auxiliary elements to ensure safe and reliable operation under the high temperatures and pressures required for the experiments. The apparatus described here is inspired by previously reported batch equipment, but has the versatility of co‐injecting gas mixtures. The capacity of the vessel is 600 mL and the system is capable of applying pressures from ambient to 5000 psi (345 bar), and temperatures from ambient to 350 °C under batch continuous stirring conditions. These ranges of pressure and temperature can cover and even exceed the conditions relevant for the majority of subsurface sequestration studies. The interior wetted parts of the vessel are all in Hastelloy C276 (a Ni‐Cr‐Mo alloy) to be resistant to the corrosiveness of gases such as SO2. The system was tested by studying the sequestration of CO2‐SO2 mixtures in ferric (FeIII) iron‐containing sediments, as SO2 has been shown to reduce FeIII to FeII and permanently trap CO2 as the mineral siderite (FeCO3). A series of batch trials were conducted to demonstrate the experimental apparatus design efficacy along with the system´s behavior. The apparatus functioned well during the course of the experiments proving that this set‐up is a useful research tool to investigate the effect of impurities present in the flue gas from fossil fuel combustion in the geological storage of CO2.