bluuebunny/crossref_metadata_2025_split huggingface dataset:
Semantic Feature Analysis: Incorporating Typicality Treatment and Mediating Strategy Training to Promote Generalization
Authors: Wambaugh Julie L. , Mauszycki Shannon , Cameron Rosalea , Wright Sandra , Nessler Christina 
Published: May 2013

Purpose
This investigation was designed to examine the generalization effects of semantic treatment for word retrieval deficits in people with aphasia. Semantic feature analysis (SFA; Boyle & Coelho, 1995), typicality treatment (Kiran & Thompson, 2003), and mediating strategy training were combined to maximize potential generalization effects.

Method
Treatment, which included SFA and a semantic feature judgment task, was conducted with 9 participants with chronic aphasia in the context of multiple baseline designs across behaviors. Typical and atypical exemplars were trained across animate and inanimate categories. Treatment was sequentially modified to overtly train the use of SFA as a mediating strategy.

Results
Eight of the 9 participants demonstrated improvements in naming of trained stimuli. Positive generalization effects were limited overall; possible response generalization was evident for 5 participants. Instruction in the use of a mediating strategy resulted in improved naming of treated words for all participants; however, generalization to untreated words did not occur.

Conclusion
Treatment using SFA resulted in improved naming of treated typical and atypical exemplars in both animate and inanimate categories for 8 of 9 participants. Training in a mediating strategy also resulted in improved retrieval of experimental words. Regardless of intervention approach, generalization to untreated items was limited.
Rehabilitation in Bilingual Aphasia: Evidence for Within- and Between-Language Generalization
Authors: Kiran Swathi , Sandberg Chaleece , Gray Teresa , Ascenso Elsa , Kester Ellen 
Published: May 2013

Purpose
The goal of this study was to examine if there was a principled way to understand the nature of rehabilitation in bilingual aphasia such that patterns of acquisition and generalization are predictable and logical.

Method
Seventeen Spanish–English bilingual individuals with aphasia participated in the experiment. For each participant, three sets of stimuli were developed for each language: (a) English Set 1, (b) English Set 2 (semantically related to each item in English Set 1), (c) English Set 3 (unrelated control items), (d) Spanish Set 1 (translations of English Set 1), (e) Spanish Set 2 (translations of English Set 2; semantically related to each item in Spanish Set 1), and (f) Spanish Set 3 (translations of English Set 3; unrelated control items). A single-subject experimental multiple baseline design across participants was implemented. Treatment was conducted in 1 language, but generalization to within- and between-language untrained items was examined.

Results
Treatment for naming on Set 1 items resulted in significant improvement (i.e., effect size >4.0) on the trained items in 14/17 participants. Of the 14 participants who showed improvement, within-language generalization to semantically related items was observed in 10 participants. Between-language generalization to the translations of trained items was observed in 5 participants, and between-language generalization to the translations of the untrained semantically related items was observed in 6 participants.

Conclusion
The results of this study demonstrated within- and between-language patterns that were variable across participants. These differences are indicative of the interplay between facilitation (generalization) and inhibition.
Sensorless control of high‐power interior permanent‐magnet synchronous motor drives at very low speed
Authors: Yuan Lei , Xiao Fei , Shen Jian‐qing , Chen Ming‐liang , Shi Qiao‐ming , Quan‐feng Li 
Published: May 2013

A novel sensorless control scheme is proposed for an interior permanent‐magnet synchronous motor drives at very low speed based on sliding‐mode observer (SMO) in this study, which substitutes a sigmoid function for the sign or saturation function with a variable boundary layer, overcomes the time delay caused by the low‐pass filter and the chattering problem used in the conventional SMO. In this study, an adaptive SMO is employed to estimate the rotor speed and extended electromotive force, a three‐phase soft phase‐locked loop technology is used to estimate rotor position because of its strong robustness since under voltage phase unbalance or polluted and variable‐frequency environment. The global asymptotic stability of the proposed adaptive SMO is verified using Lyapunov stability analysis with considering motor parameter variations. Experimental results are presented to verify the principles and to demonstrate the effectiveness of the proposed method at very low speed from 2 to 17 r/min.
Infection Control Assessment after an Influenza Outbreak in a Residential Care Facility for Children and Young Adults with Neurologic and Neurodevelopmental Conditions
Authors: Azofeifa Alejandro , Yeung Lorraine F. , Peacock Georgina , Moore Cynthia A. , Rodgers Loren , DiOrio Mary , Page Shannon L. , Fowler Brian , Stone Nimalie D. , Finelli Lyn , Jhung Michael A. 
Published: May 2013

Objective.To assess the knowledge, attitudes, and practices of infection control among staff in a residential care facility for children and young adults with neurologic and neurodevelopmental conditions.Design.Self-administered survey.Setting.Residential care facility (facility A).Participants.Facility A staff (N = 200).Methods.We distributed a survey to staff at facility A. We classified staff with direct care responsibilities as clinical (ie, physicians, nurses, and therapists) or nonclinical (ie, habilitation assistants, volunteers, and teachers) and used X2 tests to measure differences between staff agreement to questions.Results.Of 248 surveys distributed, 200 (81%) were completed; median respondent age was 36 years; 85% were female; and 151 were direct care staff (50 clinical, 101 nonclinical). Among direct care staff respondents, 86% agreed they could identify residents with respiratory symptoms, 70% stayed home from work when ill with respiratory infection, 64% agreed that facility administration encouraged them to stay home when ill with respiratory infection, and 72% reported that ill residents with respiratory infections were separated from well residents. Clinical and nonclinical staff differed in agreement about using waterless hand gel as a substitute for handwashing (96% vs 78%; P = .005) and whether handwashing was done after touching residents (92% vs 75%; P = .04).Conclusions.Respondents' knowledge, attitudes, and practices regarding infection control could be improved, especially among nonclinical staff. Facilities caring for children and young adults with neurologic and neurodevelopmental conditions should encourage adherence to infection control best practices among all staff having direct contact with residents.
Specificity control for read alignments using an artificial reference genome-guided false discovery rate
Authors: Giese Sven H. , Zickmann Franziska , Renard Bernhard Y. 
Published: May 2013

Abstract
Motivation: Accurate estimation, comparison and evaluation of read mapping error rates is a crucial step in the processing of next-generation sequencing data, as further analysis steps and interpretation assume the correctness of the mapping results. Current approaches are either focused on sensitivity estimation and thereby disregard specificity or are based on read simulations. Although continuously improving, read simulations are still prone to introduce a bias into the mapping error quantitation and cannot capture all characteristics of an individual dataset.
Results: We introduce ARDEN (artificial reference driven estimation of false positives in next-generation sequencing data), a novel benchmark method that estimates error rates of read mappers based on real experimental reads, using an additionally generated artificial reference genome. It allows a dataset-specific computation of error rates and the construction of a receiver operating characteristic curve. Thereby, it can be used for optimization of parameters for read mappers, selection of read mappers for a specific problem or for filtering alignments based on quality estimation. The use of ARDEN is demonstrated in a general read mapper comparison, a parameter optimization for one read mapper and an application example in single-nucleotide polymorphism discovery with a significant reduction in the number of false positive identifications.
Availability: The ARDEN source code is freely available at http://sourceforge.net/projects/arden/.
Contact: renardb@rki.de
Supplementary information: Supplementary data are available at Bioinformatics online.
A Human Volunteer Study to Identify Variability in Performance in the Cognitive Domain of the Postoperative Quality of Recovery Scale
Authors: Royse Colin F. , Newman Stanton , Williams Zelda , Wilkinson David J. 
Published: May 2013

Abstract

Background:
The Postoperative Quality of Recovery Scale found lower than anticipated recovery in the cognitive domain. The definition of cognitive recovery did not allow for performance variability, and may have been too sensitive. This study aimed to examine variability in cognitive performance in volunteers.

Methods:
One hundred forty-three volunteers completed the cognitive domain questions at baseline, after 15 min and 40 min, and on days 1 and 3. Delivery via face-to-face interview was conducted for the first three measurements, and then randomized for day 1 and 3 measurements (face-to-face only, telephone only, telephone then face-to-face, face-to-face then telephone).

Results:
All volunteers answered orientation correctly. Mean change scores for other tests were positive, indicating a modest learning effect. There were no significant differences between methods of delivery (all P > 0.05). Due to variability in volunteers’ performances, the authors propose a new scoring system to introduce a tolerance factor in scoring cognitive recovery. The proposed revised change from baseline scores are: orientation 0 or higher, digits forward −2 or higher, digits back −1 or higher, word recall −3 or higher, and word generation −3 or higher. This resulted in approximately 95% volunteers classed as “recovered” for each test item, and recovery for the domains ranged from 82.6 to 89.1%. The initial feasibility study was reanalyzed and cognitive recovery increased at all assessment times. At 3 days, cognitive recovery was found to increase from 33.5 to 86.4%.

Conclusion:
The authors recommend adoption of the new method for scoring cognitive recovery in the Postoperative Quality of Recovery Scale. Telephone or face-to-face delivery was equivalent and either method can be reliably applied.
Esophageal Impedance Baseline Is Age Dependent
Authors: Salvatore Silvia , Salvatoni Alessandro , Van Berkel Marieke , Van Steen Kristel , Unmarino Dario , Ghanma Abdallah , Hauser Bruno , Vandenplas Yvan 
Published: May 2013

ABSTRACTObjective:Esophageal impedance (multichannel intraluminal impedance [MII]) baseline (impedance baseline [IB]) has been recently considered to be related to esophageal integrity. The aim of this study was to analyze the age effect on IB in a large population of pediatric patients.Design:A total of 816 children with symptoms of gastroesophageal reflux and submitted to MII were included. Mean IB was automatically calculated in the different MII channels (Chs) throughout 24‐hour tracings by the specific software without removing any episode of increased/decreased IB. Acid and nonacid reflux parameters and age subgroups analysis were performed. Unpaired t test, Spearman rank correlation, polynomial and regression plot, multiple regression analysis, factorial analysis of variance, and the least mean squares method were used for statistical analysis and age‐related percentile curves. P < 0.05 was considered as statistically significant.Results:Mean IB was significantly (P < 0.001) lower in younger compared with older children up to 48 months. The mean increase of IB per month was 2.9 Ω in Ch 1 and 2.3 Ω in Ch 6, but much higher in the first 36 months of life (47.5 Ω in Ch 1 and 29.9 Ω in Ch 6, respectively). From 48 months onward, there was no significant increase of the mean IB (P = 0.73). In the multiple regression analysis, only age and reflux index (but no other reflux parameters) significantly correlated with IB. Distal IB was significantly (P < 0.05) lower in patients with esophagitis and in subjects taking proton pump inhibitors compared with subjects off (any) treatment. Percentiles of IB in proximal and distal Chs were provided according to different age groups.Conclusions:IB is significantly lower in infants (especially in the first months of life) compared with older children. Low IB in both proximal and distal esophagus in young infants may be related to anatomical and functional difference other than the presence of esophagitis.
Vacuolar Transport of the Medicinal Alkaloids from Catharanthus roseus Is Mediated by a Proton-Driven Antiport
Authors: Carqueijeiro Inês , Noronha Henrique , Duarte Patrícia , Gerós Hernâni , Sottomayor Mariana 
Published: May 2013

Abstract
Catharanthus roseus is one of the most studied medicinal plants due to the interest in their dimeric terpenoid indole alkaloids (TIAs) vinblastine and vincristine, which are used in cancer chemotherapy. These TIAs are produced in very low levels in the leaves of the plant from the monomeric precursors vindoline and catharanthine and, although TIA biosynthesis is reasonably well understood, much less is known about TIA membrane transport mechanisms. However, such knowledge is extremely important to understand TIA metabolic fluxes and to develop strategies aimed at increasing TIA production. In this study, the vacuolar transport mechanism of the main TIAs accumulated in C. roseus leaves, vindoline, catharanthine, and α-3′,4′-anhydrovinblastine, was characterized using a tonoplast vesicle system. Vindoline uptake was ATP dependent, and this transport activity was strongly inhibited by NH4 + and carbonyl cyanide m-chlorophenyl hydrazine and was insensitive to the ATP-binding cassette (ABC) transporter inhibitor vanadate. Spectrofluorimetry assays with a pH-sensitive fluorescent probe showed that vindoline and other TIAs indeed were able to dissipate an H+ gradient preestablished across the tonoplast by either vacuolar H+-ATPase or vacuolar H+-pyrophosphatase. The initial rates of H+ gradient dissipation followed Michaelis-Menten kinetics, suggesting the involvement of mediated transport, and this activity was species and alkaloid specific. Altogether, our results strongly support that TIAs are actively taken up by C. roseus mesophyll vacuoles through a specific H+ antiport system and not by an ion-trap mechanism or ABC transporters.
Motivations for energy efficiency refurbishment in owner‐occupied housing
Authors: Organ Samantha , Proverbs David , Squires Graham 
Published: May 2013

PurposeThe existing housing stock needs substantial adaptation to meet national and international carbon reduction targets. The largest proportion of housing is owner‐occupied, and will require improvement works which go beyond those measures provided through the Green Deal and similar programmes. Therefore, the motivation of owner‐occupiers to perform more substantial energy efficiency refurbishments is essential to facilitate greater action. This paper aims to address these issues.Design/methodology/approachA synthesis of the extant literature from a range of disciplines reveals the role of motivation and the factors influencing motivation and pro‐environmental action in the context of the home. Based on this synthesis of the literature, a new motivation model for energy efficiency refurbishment in the owner‐occupied housing stock is then described.FindingsThe study has found that multiple factors affect motivation to refurbish in the owner‐occupied housing stock. Key motivations for energy efficient refurbishment can be categorized into the broad themes of economic, social, and environmental motivations. These motivations will be affected by a wide number of interrelated internal and external factors and mediated by the emotions of the individual. The model presented demonstrates the relationship between the multiple factors that affect energy efficiency refurbishment in relation to specific contexts.Originality/valueThe study represents a potential addition to motivational theory and concepts for use within the field of energy efficient refurbishment of the owner‐occupied housing stock. Implications for future government policy and towards raising the motivation of owner‐occupiers are identified: it can be used to shape national and local policy and information campaigns to motivate energy efficiency refurbishment in the owner‐occupied housing stock. To be successful, this should take differing internal factors and contexts into consideration and the dynamic nature of owner‐occupier motivation. The model can also be used by industry professionals to better understand the owner‐occupier customer motivations for energy efficiency refurbishment and therein provide a better service.
Export market exploitation and exploration and performance
Authors: Lisboa Ana , Skarmeas Dionysis , Lages Carmen 
Published: May 2013

Purpose
– Drawing on the resource advantage and organisational learning literatures, this paper aims to investigate the linear, moderated, complementary and non-linear effects of export market exploitation and exploration on export performance.

Design/methodology/approach
– A quantitative study was performed using an online survey. The final sample consisted of 267 Portuguese export manufacturing firms. Data were analysed using structural equation modelling.

Findings
– Export market exploitation and exploration is positively and negatively related to export performance in a linear way, respectively. Export market exploration improves export performance under high levels of export market turbulence. Balancing export market exploitation with export market exploration enhances export performance. High levels of export market exploitation provide an additional boost to performance.

Practical implications
– This study contributes to a better understanding of how market exploitation and exploration relate to performance in the export context. To enhance export performance, managers should deploy high levels of export market exploitation, pursue export market exploration in dynamic export markets, and maintain a balance between export market exploitation and exploration.

Originality/value
– This paper contributes to the export marketing field by shedding light on the complex nature of the relationships among export market exploitation, exploration and performance. Overall, the results provide novel evidence concerning the internal and external contingencies that affect the success of export market exploitation and exploration.
Acceptance of enterprise blog for service industry
Authors: Hsing Wu Chien , Kao Shu‐Chen , Lin Hsin‐Hui 
Published: May 2013

PurposeThe rapid growth of blogs over the Internet has gradually attracted the attention of enterprises that want to engage in business and develop their online communication channels for customer relationships. The study aims to develop and examine the determinants of enterprise blog (E‐Blog) adoption for the service industry. Organization size is used as a moderating factor to disclose its influence on the effects of the variables.Design/methodology/approachThe research model of the empirical study integrates three composites: social exchange theory, innovation diffusion theory, and organization dynamics. For the results, data are analyzed by using factor analysis to derive the actual composites and structural equation model to test the hypotheses.FindingsThe main results show the following findings. First, social exchange via E‐Blog fosters enterprise reputation. Second, enterprises are doubtful whether they can build online relationships via E‐Blog with their customers and E‐Blog visitors. Third, virtual trust and the unknown virtual social structure are barriers for enterprises in using E‐Blog. Fourth, E‐Blog adopters are likely to be purpose‐sensitive as the numbers of blog type increase.Practical implicationsThe research findings reveal that E‐Blog vendors and agents should emphasize reputation development to attract the attention of their customers (enterprises). In addition, small‐ to medium‐sized enterprises prefer the relative advantages and simplicity of E‐Blogging. In contrast, large enterprises are more concerned with competition pressure and market dynamics involved in the adoption attitude. These findings would be useful for E‐Blog service providers to analyze the requirements of their customers. In addition, E‐Blog vendors and agents should persuade enterprises adopting E‐Blog to ease competition pressure, particularly for large firms who have not adopted the technology. Finally, E‐Blog platforms and vendors should emphasize that E‐Blog can help increase reputation by attracting the attention of enterprises to adopt E‐Blogging.Originality/valueIn the virtual socialization process, the blog has been developing its own characteristics that are linked to social behaviour. This link explains social change and stability in cyberspace from the social psychology and sociology points of view. The research findings differ from those of previous research because early studies focused on individual Internet user blog participation without placing emphasis on the adoption intention of enterprises. The findings of this study will be helpful for both E‐Blog service providers and enterprises.
Factors influencing sociability in educational MMORPGs – a fuzzy AHP approach
Authors: Lee Chun‐Chia , Hwa Hsu Shang , Chang Jen‐Wei 
Published: May 2013

PurposeSociability is considered to be important to the success of educational MMORPGs. The purpose of this study was to access the relative weights of these sociability factors which the authors garnered from the literature on educational MMORPGs.Design/methodology/approachThe authors used fuzzy‐AHP approach to access the relative weights of these sociability factors they garnered from the literature on educational MMORPGs. To do this, a questionnaire using a pair‐wise comparison data input format was administered to 242 school teachers to gather assessments for the factors.FindingsThe authors found five most important factors affecting sociability – cooperation, team‐based reward, discussion of strategy, reputation, and social navigation.Originality/valueAlthough prior studies have identified various factors that facilitate sociability in educational MMORPGs, the relative importance of these factors has not been determined. The results can not only be used to help educational MMORPG developers focus on the most important sociability factors and propose specific guidelines for designing educational MMORPGs, but can also identify the best design strategy for promoting sociability of educational MMORPGs.