bluuebunny/crossref_metadata_2025_split huggingface dataset:
Low‐Threshold Wavelength‐Switchable Organic Nanowire Lasers Based on Excited‐State Intramolecular Proton Transfer
Authors: Zhang Wei , Yan Yongli , Gu Jianmin , Yao Jiannian , Zhao Yong Sheng 
Published: April 2015

AbstractCoherent light signals generated at the nanoscale are crucial to the realization of photonic integrated circuits. Self‐assembled nanowires from organic dyes can provide both a gain medium and an effective resonant cavity, which have been utilized for fulfilling miniaturized lasers. Excited‐state intramolecular proton transfer (ESIPT), a classical molecular photoisomerization process, can be used to build a typical four‐level system, which is more favorable for population inversion. Low‐power driven lasing in proton‐transfer molecular nanowires with an optimized ESIPT energy‐level process has been achieved. With high gain and low loss from the ESIPT, the wires can be applied as effective FP‐type resonators, which generated single‐mode lasing with a very low threshold. The lasing wavelength can be reversibly switched based on a conformation conversion of the excited keto form in the ESIPT process.
Adsorptive recovery of high value essential oil from kewda (Pandanus fascicularis Lam) distillation condensate
Authors: Rout Prasant Kumar , Rao Y.  Ramachandra , Prakash Om , Khare Puja 
Published: April 2015

AbstractKewda (Pandanus fascicularis Lam) essential oil was enriched with phenylethyl methyl ether (65–77%), terpinen‐4‐ol (13–18%) and α‐terpineol (1–3%), which were definitely soluble in distillation condensate. The solubility of phenylethyl methyl ether, terpinen‐4‐ol and α‐terpineol in water were more than 1000 ppm. Adsorption performance of single‐solutes and multi‐solutes over Amberlite‐resins and Indion‐resins were elucidated. XAD‐4 and Indion 1014 MN‐2 were most suitable because of their higher loading capacities of 2.2–3.2 mmol g−1 and 2.3–3.6 mmol g−1, respectively. Temkin adsorption isotherm was best fitted to the experimental results. Adsorption was followed Pseudo‐second order, Ritche's‐second order and Elovich's equation to validate the kinetics of chemisorption. Column breakthrough results revealed that the water soluble essential oil was recovered from the distillation condensate through a resin bed. Then the adsorbed solutes were desorbed from the resins with elution in ethanol to achieve complete recovery of high value essential oil from the distillation condensate. © 2015 Curtin University of Technology and John Wiley & Sons, Ltd.
Morphology and Topography of the Celiac Plexus in Degu (Octodon Degus)
Authors: Kuchinka Jacek , Nowak Elżbieta , Kuder Tadeusz , Szczurkowski Aleksander 
Published: April 2015

ABSTRACTHere, we investigate the morphology and topography of the celiac plexus components in degu (Octodon degus). The study was performed using six adult individuals of both sexes. Macromorphological observations were performed using a derivative of the thiocholine method specially adapted for this study type (Gienc, 1977). The classical H&E technique was used for analysis of the cytoarchitectonic of the ganglion, and the AChE (Karnovsky and Roots, 1964) and SPG (De la Torre, 1980) techniques to observe cholinergic and adrenergic activity. The celiac plexus of degu is located on the ventral and lateral surface of the abdominal aorta, at the level where the celiac artery separates from the aorta. This structure consists of two large and two smaller aggregations of neurocytes connected with postganglionic fibers. Histochemical investigations have demonstrated the mainly cholinergic characteristic of the intraganglionic and postganglionic fibers of the celiac plexus, while the adrenergic fibers accompanied only the blood vessels and neurocytes revealed differentiation of adrenergic activity. Histological analysis revealed that neurocytes occupied about half of the cross‐section area, with the nerve fibers, connective tissue, and blood vessels forming the remaining part. Ganglionic cells were oval, and usually contained a single nucleus, although two nuclei were sometimes observed. Anat Rec, 298:1880–1884, 2015. © 2015 Wiley Periodicals, Inc.
Improvement of biomass production and glucoamylase activity by Candida famata using factorial design
Authors: Mosbah Habib , Aissa Imen , Hassad Nahla , Farh Dhaker , Bakhrouf Amina , Achour Sami 
Published: April 2015

AbstractTo improve biomass production and glucoamylase activity (GA) by Candida famata, culture conditions were optimized. A 23 full factorial design (FFD) with a response surface model was used to evaluate the effects and interactions of pH (X1), time of cultivation (X2), and starch concentration (X3) on the biomass production and enzyme activity. A total of 16 experiments were conducted toward the construction of an empiric model and a first‐order equation. It was found that all factors (X1, X2, and X3) and their interactions were significant at a certain confidence level (P < 0.05). Using this methodology, the optimum values of the three tested parameters were obtained as follows: pH 6; time of cultivation 24 H and starch concentration 7 g/L, respectively. Our results showed that the starch concentration (X3) has significantly influenced both dependent variables, biomass production and GA of C. famata. Under this optimized medium, the experimental biomass production and GA obtained were 1.8 ± 0.54 g/L and 0.078 ± 0.012 µmol/L/Min, about 1.5‐ and 1.8‐fold, respectively, higher than those in basal medium. The (R2) coefficients obtained were 0.997 and 0.990, indicating an adequate degree of reliability in the model. Approximately 99% of validity of the predicted value was achieved.
Comparative studies on the interactions of baicalein and Al(III)–baicalein complex with human serum albumin
Authors: Wang Jing , Wang Qing , Wu Di , Yan Jin , Wu You , Li Hui 
Published: April 2015

AbstractA new potential drug aluminum(III)–baicalein complex (ALBC) was synthesized and characterized. The binding mechanisms of baicalein (BC) and ALBC to human serum albumin (HSA) under simulative physiological conditions were investigated, in order to understand the pharmacokinetics of BC and ALBC. Fluorescence spectroscopy results suggested that the binding level of BC is higher than that of ALBC. Results of UV–vis, synchronous fluorescence, 3D fluorescence, circular dichroism and Fourier transform infrared spectroscopic analyses consistently demonstrated that the conformation of HSA was altered when bound to BC or ALBC. The distance between HSA as a donor and BC (or ALBC) as an acceptor was determined via fluorescence resonance energy transfer. The results of competitive experiments and molecular docking studies indicated that BC was located in site I (subdomain IIA) on HSA and that ALBC was bound to HSA mainly within site II (subdomain IIIA). Copyright © 2015 John Wiley & Sons, Ltd.
Adaptive cloud simulation using position based fluids
Authors: Ferreira Barbosa Charles Welton , Dobashi Yoshinori , Yamamoto Tsuyoshi 
Published: April 2015

AbstractIn this paper, we propose a method for the simulation of clouds using particles exclusively. The method is based on position based fluids, which simulates fluids using position constraints. To reduce the simulation time, we have used adaptive splitting and merging to concentrate computation on regions where it is most needed. When clouds are formed, particles are split so as to add more details to the generated cloud surface and when they disappear, particles are merged back. We implement our adaptive method on the Graphics Processing Unit (GPU) to accelerate the computation. While the splitting portion is easily parallelizable, the merge portion is not. We develop a simple algorithm to address this problem and achieve reasonable simulation times. Copyright © 2015 John Wiley & Sons, Ltd.
Cell‐free fetal DNA in the maternal circulation originates from the cytotrophoblast: proof from an unique case
Authors: Hochstenbach Ron , Nikkels Peter G. J. , Elferink Martin G. , Oudijk Martijn A. , van Oppen Carla , van Zon Patrick , van Harssel Jeske , Schuring‐Blom Heleen , Page‐Christiaens Godelieve C. M. L. 
Published: April 2015

Key Clinical MessageNoninvasive prenatal testing (NIPT) and direct karyotyping of cytotrophoblast were normal for a male fetus, but cultured chorionic villus mesenchymal cells and umbilical cord fibroblasts showed nonmosaic trisomy 18. This observation provides direct evidence for the cytotrophoblastic origin of cell‐free fetal DNA and yields a biological explanation for falsely reassuring NIPT results.
Anesthesia for deep brain stimulation in traumatic brain injury‐induced hemidystonia
Authors: Jani Jill M. , Oluigbo Chima O. , Reddy Srijaya K. 
Published: April 2015

Key Clinical MessageDeep brain stimulation in an awake patient presents several unique challenges to the anesthesiologist. It is important to understand the various stages of the procedure and the complexities of anesthetic management in order to have a successful surgical outcome and provide a safe environment for the patient.
Intramolecular Hydrogen Bonds Quench Photoluminescence and Enhance Photocatalytic Activity of Carbon Nanodots
Authors: Yang Pengju , Zhao Jianghong , Zhang Lexi , Li Li , Zhu Zhenping 
Published: April 2015

AbstractUnderstanding the photoluminescence (PL) and photocatalytic properties of carbon nanodots (CNDs) induced by environmental factors such as pH through surface groups is significantly important to rationally tune the emission and photodriven catalysis of CNDs. Through adjusting the pH of an aqueous solution of CNDs, it was found that the PL of CNDs prepared by ultrasonic treatment of glucose is strongly quenched at pH 1 because of the formation of intramolecular hydrogen bonds among the oxygen‐containing surface groups. The position of the strongest PL peak and its corresponding excitation wavelength strongly depend on the surface groups. The origins of the blue and green emissions of CNDs are closely related to the carboxyl and hydroxyl groups, respectively. The deprotonated COO− and CO− groups weaken the PL peak of the CNDs and shift it to the red. CNDs alone exhibit photocatalytic activity towards degradation of Rhodamine B at different pH values under UV irradiation. The photocatalytic activity of the CNDs is the highest at pH 1 because of the strong intramolecular hydrogen bonds formed among the oxygen‐containing groups.
Controllable Galvanic Synthesis of Triangular Ag–Pd Alloy Nanoframes for Efficient Electrocatalytic Methanol Oxidation
Authors: Xu Lin , Luo Zhimin , Fan Zhanxi , Yu Sijia , Chen Junze , Liao Yusen , Xue Can 
Published: April 2015

AbstractTriangular Ag–Pd alloy nanoframes were successfully synthesized through galvanic replacement by using Ag nanoprisms as sacrificial templates. The ridge thickness of the Ag‐Pd alloy nanoframes could be readily tuned by adjusting the amount of the Pd source during the reaction. These obtained triangular Ag–Pd alloy nanoframes exhibit superior electrocatalytic activity for the methanol oxidation reaction as compared with the commercial Pd/C catalyst due to the alloyed Ag–Pd composition as well as the hollow‐framed structures. This work would be highly impactful in the rational design of future bimetallic alloy nanostructures with high catalytic activity for fuel cell systems.
Cleavage of a PN Bond in a Urea‐Containing (Ph2P(R)PPh2)‐Bridged Dinuclear Gold(I) Thiolate Complex by Fluoride and a Mechanistic Insight
Authors: He Xiaoming , Lam Wai Han , Cheng Eddie Chung‐Chin , Yam Vivian Wing‐Wah 
Published: April 2015

AbstractA urea‐containing, (Ph2P(R)PPh2)‐bridged, dinuclear, gold(I) thiolate complex, [Au2{Ph2PN(C6H4OMe‐4)PPh2}(SC6H4NHCONHC6H5)2] (1) was designed and synthesized and its photophysical and anion recognition properties studied. The results show that 1 has a high selectivity toward F−. Upon addition of F−, the yellow solution was decolorized, and drastic changes of emission and 1H and 31P{1H} NMR signals were observed. Interestingly, these changes are attributed to fluoride‐assisted PN bond hydrolysis, instead of the expected hydrogen‐bonding interactions with the urea receptor. Similar changes were observed for two other basic anions, AcO− and H2PO4−, but to a much lesser extent; and these anions were found to bind to the urea receptor at the same time. On the other hand, Cl− was found to only bind to the urea moiety through hydrogen‐bonding interactions. Further studies with the control complex [Au2{Ph2PN(C6H4OMe‐4)PPh2}Cl2] (2) indicate that F− assists the hydrolysis process via cleavage of the PN bond. DFT calculations were performed to study the reaction mechanism for the fluoride‐assisted PN bond hydrolysis of 2; these provide a better insight into the role of fluoride in the hydrolysis.
Hyper‐star graphs: Some topological properties and an optimal neighbourhood broadcasting algorithm
Authors: Zhang F. , Qiu K. , Kim J. S. 
Published: April 2015

SummaryHyper‐star graph HS(2n,n) was introduced to be a competitive model to both hypercubes and star graphs. In this paper, we study its properties by (1) giving a closed form solution to the surface area of HS(2n,n), (2) discussing its Hamiltonicity by establishing an isomorphism between the graph and the well‐known middle levels problem, and (3) showing that full binary trees can be embedded into HS(2n,n) with dilation 1. We also develop a single‐port optimal neighbourhood broadcasting algorithm for HS(2n,n). Copyright © 2015 John Wiley & Sons, Ltd.
Poly(2‐vinylpyridine)‐Based Polymers as an Efficient Affinity Material for the Detection of Airborne Phenol
Authors: Linke Alexander , Schmidt Manfred , Waldvogel Siegfried R. 
Published: April 2015

AbstractPhenol is an omnipresent compound in various situations. Its acute toxicity makes alternative tracing methods desirable. Highly potent affinity materials based on polyvinyl pyridine allow an efficient tracing of this particular airborne compound. Their performance over, for example, benzene is tremendously superior. In combination with a simple cyclodextrin derivative an array allows differentiation among such aromatic competitors. Owing to the high affinity of these polymers for phenol, quartz microbalance‐based tracing is able to detect phenol below the parts per million range. This was previously not possible with other affinity materials.
The EJHF last Editor's legacy: how can a high impact factor be built?
Authors: Metra Marco 
Published: April 2015

AbstractThe European Journal of Heart Failure (EJHF) has reached a high impact factor making it one of the most important cardiology journals. I discuss herein what could be the main causes of such high ranking. Publication of the European Society of Cardiology guidelines for the diagnosis and treatment of acute and chronic heart failure has had the most important role with a number of citations, which has been approximately 10 times that of the other most cited articles of the same year. Other position statements, reviews, design papers, and research articles about landmark topics have given major contributions. With respect to the different clinical presentations, articles about heart failure with preserved ejection fraction and about advanced heart failure have gained many citations. Epidemiology, biomarkers, medical treatment, and devices have attracted most of the interest.In conclusion, being able to look ahead and to publish what is going to become important remains a major challenge. That of EJHF has been a success story, to date, and learning from the past may help to build upon this achievement.
Early intervention and long‐term outcome with cardiac resynchronization therapy in patients without a history of advanced heart failure symptoms
Authors: Herscovici Romana , Kutyifa Valentina , Barsheshet Alon , Solomon Scott , McNitt Scott , Polonsky Bronislava , Lee Andy Y. , Zareba Wojciech , Moss Arthur J. , Goldenberg Ilan 
Published: April 2015

AimsMADIT‐CRT showed that cardiac resynchronization therapy with a defibrillator (CRT‐D) improves long‐term outcomes in currently mildly symptomatic heart failure (HF) patients with LBBB regardless of the presence of prior advanced HF symptoms. We aimed to evaluate the long‐term benefit of CRT‐D in patients who never experienced advanced HF symptoms prior to device implantation.Methods and resultsInteraction term analysis was used to compare the clinical and echocardiographic benefit of CRT‐D vs. implantable cardioverter defibrillator (ICD)‐only therapy during long‐term follow‐up (median 5.6 years) between LBBB patients with or without a history of advanced HF [defined as NYHA class ≥ III or past hospitalization for worsening HF >3 months prior to enrolment in MADIT‐CRT (n = 529 and 752, respectively)]. Multivariable analysis showed that treatment with CRT‐D was associated with a significant reduction in the risk of HF or death during long‐term follow‐up regardless of the presence of prior advanced HF symptoms [hazard ratio 0.53 (P < 0.001) and 0.47 (P < 0.001) in the respective groups of patients with and without prior advanced HF; interaction P for the difference = 0.58]. Echocardiographic response to CRT at 1 year was also similar between the two groups (P > 0.10 for all comparisons).ConclusionOur findings suggest that treatment with CRT‐D is associated with pronounced echocardiographic and long‐term clinical benefit in patients with LV dysfunction and LBBB who never experienced advanced HF symptoms. These data further emphasize the benefit of early intervention with CRT in this population.
Semiconducting BiOCuSe Thermoelectrics and Its Metallic Derivative Bi2YO4Cu2Se2
Authors: Chou Ta‐Lei , Tewari Girish C. , Chan Ting‐Shan , Hsu Ying‐Ya , Chen Jin‐Ming , Yamauchi Hisao , Karppinen Maarit 
Published: April 2015

AbstractZrCuSiAs‐type mixed‐anion oxychalcogenides and oxypnictides form a massive family of functional materials readily tailored to host diverse transport properties. Here we investigate semiconducting BiOCuSe, which has been considered as a promising candidate for intermediate‐temperature thermoelectric applications, and its intergrowth derivative Bi2YO4Cu2Se2, by using X‐ray absorption spectroscopy. Stronger anisotropy and bond covalency are revealed for the latter phase, and in contrast to the simple charge‐balance scenario of [Bi3+O2–]+[Cu+Se2–]– in the former phase, mixed‐valence Cu+/Cu2+ with a single coordination sphere is seen in the selenide block of Bi2YO4Cu2Se2, which gives rise to a metallic electrical conductivity.
Model Studies on Peroxidic Glutathione Transferase (GST) Inhibitors: C5‐Methylated 1,2,4‐Trioxanes with C6‐Acrylate Side Chains
Authors: Griesbeck Axel G. , Maaßen Andreas , Bräutigam Maria , Pietsch Markus 
Published: April 2015

AbstractThe 1,2‐hydroxy hydroperoxide 7 was obtained with high threo diastereoselectivity from the ester‐conjugated allylic alcohol 6 through a porphyrin‐sensitized singlet oxygen ene reaction. Compound 7 was used as substrate for peroxy(trans)acetalization with aldehydes, orthoesters, and acetals, catalyzed by boron and indium Lewis acids, as well as by PPTS as a Brønsted acid catalyst (for trioxane 10). The 1,2,4‐trioxane 8 was formed with high diasteroselectivity with all‐equatorially positioned substitutents at C‐3, C‐5, and C‐6. Additionally, perorthoester 9 was obtained by indium(III)‐catalyzed condensation of an orthoester with the hydroperoxide 7. The new compounds 8 and 9 exhibited moderate inhibition of human placental glutathione transferase (GST), comparable to that shown by the 5‐unsubstituted model trioxane 11.
Mild Oxidative Cleavage of 9‐BBN‐Protected Amino Acid Derivatives
Authors: Ankner Tobias , Norberg Thomas , Kihlberg Jan 
Published: April 2015

AbstractProtection of the amino acid moiety using 9‐BBN is an effective method to enable side chain manipulations in synthesis of complex amino acids. We investigated the standard, mild method for deprotection of the 9‐BBN group in methanolic chloroform, and found that it relies on a slow oxidation mediated by molecular oxygen. Building on this insight, we have developed a method that allows for a fast and selective deprotection using simple peroxy acid reagents. After Fmoc protection, products were isolated in >90 % yield for a series of amino acid derivatives, including a galactosylated derivative of hydroxylysine.
Choice of Reference Electrode is Critical for Potentiometric Whole Cell‐based Sensor
Authors: Kolli Ramya , Kaivosoja Emilia , Levon Kalle 
Published: April 2015

AbstractCells have a net negative outer charge which gives rise to a potential difference in a potentiometric set up. Here, Triton X‐100 was used as a model toxin and the cell death was monitored by the potential change, noticed as decrease in negativity. Hence, cytotoxicity can be tested in vitro and real‐time using potentiometry. However, silver ions (Ag+) and/or silver chloride ions (AgCl2)−1 lead to cell death when we used the standard Ag/AgCl reference electrode with 3 M NaCl as filling solution. Our further experimentation showed that PBS as filling solution was biocompatible and also gave stable potentiometric profiles.
Peripheral T‐cell lymphoma with unusual clinical presentation of rhabdomyolysis
Authors: Liu Zhiyu , Medeiros L. Jeffrey , Young Ken H. 
Published: April 2015

AbstractPrimary extranodal lymphoma is known to occur in nose, gastrointestinal tract, skin, bone, and central nervous system. However, it is extremely rare for primary lymphoma to arise in skeletal muscle. We report a case of a 32‐year‐old man who presented initially with fever and fatigue. He had a history of alcohol abuse. Laboratory studies and computerized tomography scan showed results consistent with rhabdomyolysis, but the cause of the rhabdomyolysis was undetermined. After biopsy of abdominal skeletal muscle with histologic examination and T‐cell receptor gamma chain gene rearrangement analysis, the diagnosis of peripheral T‐cell lymphoma was established. After two cycles of the cyclophosphamide, doxorubicin, vincristine, prednisone, and etoposide regimen, the patient's symptoms greatly improved. This is the third reported case of peripheral T‐cell lymphoma arising in skeletal muscle reported in the literature and which presented clinically with rhabdomyolysis. The alcohol abuse during the clinical course likely worsens the pathologic process of the rhabdomyolysis. Copyright © 2015 John Wiley & Sons, Ltd.
Enhancement impedance transforming ratios of coupled line impedance transformer with wide out‐of‐band suppression characteristics
Authors: Kim Phirun , Chaudhary Girdhari , Jeong Yongchae 
Published: April 2015

ABSTRACTThis article presents the design of an impedance transformer (IT) with wide out‐of‐band suppression characteristics. The wide out‐of‐band suppression characteristics can be obtained by loading several transmission zeros in the lower and upper out‐of‐bands. For experimental validation, a 50‐to‐10 Ω IT was implemented at a center frequency (f0) of 2.6 GHz for the long term evolution signal. The measured results are in good agreement with the simulations, showing a return loss higher than 20 dB over a passband bandwidth of 0.35 GHz (2.35–2.7 GHz) and out‐of‐band suppression better than 18 dB from DC to 1.78 GHz and from 3.45 to 6.97 GHz. © 2015 Wiley Periodicals, Inc. Microwave Opt Technol Lett 57:1600–1603, 2015