bluuebunny/crossref_metadata_2025_split huggingface dataset:
BIOSTRATIGRAPHY, LITHOLOGY AND GEOCHEMISTRY OF THE LOWER AND MIDDLE CAMBRIAN ROCKS IN THE KYULENKE RIVER BASIN: FIRST RESULTS OF BOREHOLE CORE STUDY
Authors: КОРОВНИКОВ И.В. , ВАРАКСИНА И.В. , КОНТОРОВИЧ А.Э. , ПАРФЕНОВА Т.М. 
Published: July 2024

Выполнено комплексное биостратиграфическое, литологическое и геохимическое изучение пород керна скважин, пробуренных в бассейне реки Кюленке. Исследование найденных ископаемых остатков, состава пород, анализ распределения трилобитов и изменения литолого-геохимических характеристик отложений позволили выявить особенности строения маркирующих горизонтов, провести корреляцию разрезов скважин и обнажений, сопоставить отдельные интервалы кембрийских отложений с региональными зонами Юдомо-Оленекского фациального региона Сибирской платформы. Установлено, что породы куонамской свиты обогащены ураном (U), наблюдается прямая связь между содержанием U и органическим углеродом (С орг) пород, характерная для черносланцевых отложений нижнего и среднего кембрия из обнажений востока Сибирской платформы. Впервые выявлена связь радиоактивности пород по гамма-каротажу с содержанием U и С орг в породах кембрия.
We have studied biostratigraphy, lithology and geochemistry of drill cores from the Kyulenke River basin. The study of fossil remains and rock compositions, the analysis of trilobite distributions and changes in the lithological and geochemical characteristics of the sediments made it possible to identify structural features of the marker horizons, to correlate borehole sections and outcrops, to compare individual Cambrian intervals and the regional zones of the Yudoma-Olenek facies region of the Siberian Platform. The study has shown rocks of the Kuonamka Fomation to be enriched in uranium (U) and revealed a direct relationship between the contents of U and organic carbon (C org) in the analyzed rocks, typical for the lower and middle Cambrian black shale deposits sampled from the outcrops in the eastern parts of the Siberian Platform. For the first time, a relationship of rock radioactivity by gamma-ray logging with the contents of U and C org in Cambrian rocks was established.
Effect of the delivery route and dose of multipotent mesenchymal stem cells on the efficacy of cell therapy (review)
Authors: Pak N. V. , Murzina E. V. , Aksenova N. V. , Krylova T. G. , Aleksandrov V. N. 
Published: July 2024

Multipotent mesenchymal stem cells (MMSCs) are known to be excellent therapeutic agents. Apart from their ability to differentiate into various cell types, and thus participate in the repair of injured tissues and organs, they can influence the regeneration process through secretion of paracrine factors. Thus, MMSC therapy represents a special type of medical intervention that has both a systemic range of therapeutic efficacy and local activity on individual sites of an organ. Over the past decades, MMSC therapy has continuously been in a cautious transition from research development to clinically approved therapies. Clinical trial data has shown that this therapy is rarely associated with severe adverse events, is well tolerated and quite safe in the short-term period. However, it has a number of limitations for use, mainly due to the risk of malignant transformation. The success of stem cell transplantation in the treatment of various diseases has been confirmed both in preclinical studies and in clinical practice. The main issues that arise when assessing the therapeutic efficacy of MMSC-associated therapy are the type of cells (adipogenic, bone marrow, etc.), delivery route, number of cells injected, and the optimal number of injections. There is a growing body of experimental and clinical evidence suggesting that both an adequate delivery route and an adequate dose can increase the likelihood of success of MMSC-associated. Each cell delivery route has costs and benefits. However, there is generally contradictory evidence on the comparative efficacy of different cell delivery routes. The optimal dose of transplanted cells is also debated, as high MMSC doses may increase the risks of complications and may not have the proper effect both when administered systemically and locally. These aspects require further systematization of available data to maximize the effect of cell therapy by selecting the safest and most appropriate approaches.
Expert consensus on the terminology, diagnostics and management of persisting symptoms after concussion with a focus on mental health, postural stability, electroencephalogram and balance testing: A cross-sectional Delphi-like survey
Authors: Lumb Michael James , Snegireva Nadja , Welman Karen 
Published: July 2024

Background: Persisting symptoms after concussion (PSaC) are a pathological manifestation of head injuries that present with symptoms after the acute phase of head trauma has subsided. Insufficient research about PSaC has led to gaps in knowledge and incorrect terminology being applied. Furthermore, gaps exist in standardised assessment protocols and understanding of mental health symptoms associated with sports.
Objectives: The study aimed to; 1) Determine expert consensus on appropriate terminology for symptoms lasting >4 weeks, 2) Investigate associations with mental health and postural stability symptoms, 3) Evaluate experts’ views on quantitative balance and electroencephalogram (EEG) testing.
Methods: A Delphi-like survey was designed in REDCap and sent to identified experts in the field of sports-related concussions (SRC). Expert consensus was defined as ≥ 75% agreement.
Results: Expert consensus identified the following mood and motor control symptoms being associated with PSaC: increases in emotional state (80%), irritability (87%), nervousness (87%), sadness (80%), balance impairment (80%), dizziness (87%) and feeling slow (80%). Numbness and tingling were not considered longer-term effects (80%). Additionally, 93% of respondents acknowledged mental health symptoms as potential longer-term effects, with 80% agreeing on inadequate current management. Respondents indicated PSaC are only somewhat adequately managed (73%) or not managed well enough (27%). The use of EEG and quantitative balance testing remains open for debate. The survey response rate was 21%.
Conclusion: Improving mental health management for athletes with PSaC and standardising terminology is crucial. Future research is required to establish effective diagnosis and treatment methods. Addressing these issues may result in better care and safer return to play for athletes.
Application of TLC and HPLC/MS methods in the study of the interaction of N-phenytaconimide with 3-methyl-1-phenyl-5-aminopyrazole
Authors: Shmoilova Yana Yu. , Kovygin Yuri A. , Shikhaliev Khidmet S. , Vandyshev Dmitry Yu. 
Published: July 2024

The thin layer chromatography (TLC) method is widely used for the rapid analysis of reaction masses in fine organic synthesis. The use of this method allows not only assessing the purity of substances and identify individual components, but also to monitor the progress of synthesis [1-3]. To reliably identify a large number of substances in multicomponent systems and determine the degree of conversion of starting substances, the HPLC-MS analysis method can be used [4-6].
It was previously shown that N-arylitaconimides are easily recycled by various binucleophiles when they are boiled together in various solvents, but data on the choice of reaction conditions were scattered and unsystematized. The purpose of this study was to investigate the possibility of combining several chromatographic methods to control and optimize the synthesis of pyrazolo[3,4-b]pyridine formed during the reaction N-phenylitaconimide and 3-methyl-1-phenyl-pyrazol-5-amine.
The interaction of the components was carried out in low-polar as well as polar protic and aprotic solvents. For the control of the completeness of the reaction, thin layer chromatography on TLC Silica gel 60 F254 (Merck) plates was used, chloroform, methanol and their mixtures in various ratios were used as eluents. The components of the reaction mass were correlated with the declared structures using HPLC/MS studies.
It was shown that the interaction of N-phenylitaconimide with 3-methyl-1-phenylpyrazol-5-amine in all studied systems for 10-15 hours did not lead to the complete conversion of the reagents. The use of aprotic solvents, both polar and low-polar, did not allow obtaining preparatively significant yields of the target product. In protic solvents, the yields of pyrazolo[3,4-b]pyridine were significantly higher. It was also shown that an increase in the protonogenicity of the medium due to the addition of acetic acid led to a more complete conversion of the reagents.
The TLC and HPLC/MS data correlated well with the data on the preparative yields of pyrazolo[3,4-b]pyridine. It was found that the most suitable medium for synthesis was a mixture of propan-2-ol and acetic acid in a ratio of 25:1.
Peran Mobile Training Unit Dalam Peningkatan Sikap Mental Wirausaha Pada Penyandang Disabilitas Di Balai Latihan Kerja Situbondo
Authors: Imsiyah Niswatul , Sugiarto Galuh Pramesti , Alkornia Sylva 
Published: July 2024

Penelitian ini bertujuan mendeskripsikan Peran Mobile Training Unit Dalam Peningkatan Sikap Mental Wirausaha Pada Penyandang Disabilitas Di Balai Latihan Kerja Situbondo. Metode penelitian menggunakan jenis penelitian deskriptif dengan pendekatan kualitatif. Hasil penelitian ini adalah mobile training unit memberikan peran penting dalam memberikan akses pelatihan dengan kemudahan dalam mengikuti pelatihan, menyediakan fasilitas yang sangat lengkap untuk menunjang proses pelatihan terkait sarana dan prasarana. Kegiatan pembinaan keterampilan yang diberikan oleh instruktur pada peserta penyandang disabilitas mampu meningkatkan kemampuan personal meliputi kemampuan dasar membatik, keterampilan membatik, dan peningkatan kepercayaan diri. Kegiatan pembinaan juga mampu meningkatkan jiwa kreatif dan inovatif dengan beragamnya batik yang dibuat menggunakan teknik membatik cap, ciprat dan tulis serta variasi pewarnaan dalam batik yang dibuat. Hal tersebut, memberikan peluang usaha dengan modal keterampilan yang diperoleh melalui pelatihan Mobile Training Unit yang telah diikuti peserta disabilitas sebelumnya, ditandai dengan didirikannya kelompok usaha bersama sebagai bentuk keberlanjutan kegiatan yang telah diikuti. Kata Kunci: Peran Mobile Training Unit, Sikap Mental Wirausaha, Penyandang Disabilitas
PENERAPAN PEWARNAAN GRAF UNTUK MENINGKATKAN EFISIENSI PENJADWALAN MENGAJAR GURU DI MTS AL-KHOIRIYAH
Authors: Hamid Nur , Maghfirah Hidayatul , Su'aibah Siti , Jawad Muhammad , Khoiruman Muhammad , Hafiizh Mochammad 
Published: July 2024

Scheduling subjects in a school often gives a conflicting schedule to some teachers. On the other hand, graph theory can help to solve. One of the methods to solve the problem is implementing a coloring graph. In this paper, we apply the coloring graph using the Welch-Powell algorithm for scheduling subjects in MTs Al-Khoiriyah.Keywords: Welch-Powell algorithm, Coloring graph.
Possessive Pronouns in German
Authors: Trisiana Inggit , Hariri Tatang 
Published: July 2024

This research describes possessive pronouns in German. This study aims to describe the form and functions of noun phrases with possessive pronouns in German. The data is obtained from short stories taken from the Onleihe Goethe Institute website. The result of this study is possessive pronouns in German are formed based on the pronouns of the person or owner and the number of owners. Meanwhile, the suffixes of the possessive pronouns are formed based on the number, the case, and the article of the nouns. The addition of suffixes does not occur only in possessive pronouns but also occurs in dative plural nouns. Possessive pronouns in sentences as a case marker, meanwhile, noun phrases with possessive pronouns function as the subject, object, and adverb.
Translation of Cultural Aspects in Indonesian Folklore Nyai Anteh Sang Penunggu Bulan by Students of the German Department UM
Authors: Lawalata Kezia Gracela Widya , Rosyidah Rosyidah 
Published: July 2024

This study aims to describe the translation of cultural aspects folklore "Nyai Anteh Sang Penunggu Bulan" as well as the ideology and the translation techniques carried out by the students of the German Literature Department, Faculty of Letters, Universitas Negeri Malang. This study uses qualitative method with source language text (SL) and target language text (TL) as the data sources. Meanwhile, the data of this study are in form of SL words, phrases, and sentences that contain cultural content and student translation versions. The data was then analyzed interactively through three stages, namely data reduction, data presentation and conclusion drawing/verification. The results of this study indicate that the translation of cultural aspects in the folklore is classified into 5 cultural aspects as in the SL texts’ cultural aspects. Some aspects of the culture have been translated well by the students, while some are still not fully accepted. In translating the five cultural aspects, the students used the ideology of foreignization and domestication based on the needs of borrowing and literal translation techniques, even though the translation results are not always acceptable.
Cytomegalovirus and Epstein-Barr virus infections in pediatric patients of choledochal cyst
Authors: Kumar Yashwant , Ram Anil Kumar , Menon Prema , Kanojia Ravi Prakash , Bhatia Alka , Minz Ranjana Walker 
Published: July 2024

Association of viral infection with obstructive jaundice is well-known however frequency of cholangiotropic virus infection in pediatric choledochal cyst is not known. IgG and IgM antibodies against Cytomegalo virus (CMV) and Epstein Barr virus (EBV) in 48 children with choledochal cysts and 26 controls were analysed using ELISA. We found significantly higher anti-CMV IgG and IgM in patients (95.8% and 77.1%, respectively) compared to controls (73.1% and 42.3%) and a notable prevalence of anti-EBV antibodies among both groups (83.3% versus 65.4% IgG and 77.1% versus 46.1 for IgM in patients and controls respectively). Moreover, 79.2% of patients were positive for both anti-CMV and anti-EBV IgG, and 62.5% for both IgMs. This pilot study suggests that infection with CMV, EBV, or both is frequently seen in pediatric patients with CDC. Molecular screening and follow-up in a larger cohort is therefore required for further validation.
Evaluation of impact of adherence to inhaled therapy and critical mistakes in inhalation technique on clinical outcomes in patients with obstructive airway diseases in India
Authors: Godse Ajay , Gurjar Rakesh , Rao Namrata , Gore Shivanjali , Vijay Ria 
Published: July 2024

Adherence to inhaled therapy is more relevant in respiratory diseases because, to achieve therapeutic efficacy, it is necessary that the patient adhere to the recommended therapy as well as use their inhalers correctly with appropriate inhalation technique.This was a prospective, observational study that included 126 patients &#62;18 years of age of all genders, diagnosed with an obstructive airway disease, and prescribed inhaler medication. Adherence was assessed using the Test of Adherence to Inhalers (TAI) questionnaire, and inhaler device technique was assessed every 3 months. At the end of one year, outcome data like the number of exacerbations, the number of admissions, including critical-care admissions, the number of days of hospitalization, adverse events, and their associations were analyzed.Poor adherence to inhaled therapy was found in 40.48% of patients, with the majority of patients (69.05%) having an unwitting or ignorant pattern of non- adherence. Out of 75 patients using MDI (Metered Dose Inhaler), 34.67% had critical mistakes in technique, and out of 51 patients using Rotahaler, 23.53% had critical mistakes in technique. There was no significant relationship between level of adherence and critical mistakes with gender, BMI category, or past history of smoking. Patients with poor adherence and those with critical mistakes in inhalation technique had poor health outcomes.This study highlights the role of adherence and identifies barriers responsible for non-adherence to inhaled therapy. Identifying the behaviors responsible for non-adherence and counseling the patients on the correct inhalation technique can improve the health outcomes of chronic respiratory diseases.
Evaluation of patient perception and intraoperative bleeding in labial frenectomy: A comparision of diode laser and conventional scalpel techniques
Authors: Babu Mutthineni Ramesh , Paul Arpita , Sagar Amula Vinay , Sai Mandem Harshini 
Published: July 2024

: High frenal attachments are abnormalities corrected by surgical procedure called frenectomies. The scalpel technique is associated with pain, bleeding and postoperative discomfort. To overcome these shortcomings, in the recent times, diode lasers are gaining popularity due to less bleeding, pain during the procedure, healing outcome, and need for analgesics: To compare the bleeding during the procedure and postoperative pain in patients requiring labial frenectomy using conventional scalpel and diode laser techniques. Twenty patients with high labial frenum attachment requiring frenectomy were included in this study. Patients were randomly divided into Group A: scalpel group and Group B: diode laser group. Pain assessment using VAS, severity of intraoperative bleeding and number of analgesics used were recorded: The analysis showed that VAS score for pain was significantly lower in the laser group as compared to the scalpel group Bleeding was mild in laser group, where as in scalpel group showed moderate or severe bleeding scores Post operative use of analgesics was more in scalpel group than laser group Laser was found to be an effective alternate to scalpel in performing frenectomy procedures, more importantly it showed less bleeding, less pain perception and more patient acceptance during the procedure.
Kinerja Usaha Pelayanan Jasa Alsintan (UPJA) Berdasarkan Balanced Scorecard di Provinsi Yogyakarta
Authors: Adi Prayoga  , Mahfud Kemal , Irwanto Irwanto , Temy Indrayanti Temy 
Published: July 2024

This study aims to evaluate the performance of the Alsintan Service Business (UPJA) in the Beginner class, Developing class, and Professional class. The research was conducted using survey techniques and analyzed descriptively and qualitatively using a balanced scorecard (BSC) approach. UPJA samples were determined purposively, namely UPJA that represents each class: UPJA Sumber Makmur as UPJA Professional class, UPJA OJHA as UPJA Beginner class in Sleman Regency, and UPJA Tirtosari as UPJA Developing class in Gunungkidul Regency. Respondents were UPJA managers and employees. The results showed that, based on the financial perspective, the performance of the UPJA Beginner class and UPJA Developing class was fairly good, while the UPJA Professional class was good. Based on the customer's perspective, UPJA's performance in all classes falls into the good category. Based on the perspective of internal business processes, the performance of the three UPJA classes has innovated the development of service business services and has carried out service business operations in the medium category. Based on the perspective of learning and growth, the performance of all UPJA classes already provides satisfactory facilities for their employees. However, the UPJA Beginner class and Developing class need to improve the ability of its operators through training.

Keywords: agricultural machine tools service business, balanced scorecard, performance analysis, UPJA
Pengaruh Pupuk Kotoran Sapi dan Plant Growth Promoting Rhizobacteria pada Produksi Tanaman Buncis
Authors: Anggi Bimantara Andharesta  , Sundahri Sundahri 
Published: July 2024

The productivity of common beans has fluctuated in the last 5 years. The decrease and increase in productivity occur due to decreased soil quality due to a lack of organic matter. Plant productivity with excessive use of inorganic fertilizers can reduce soil fertility. The solution to restoring microbial activity and soil fertility levels can be taken through a nature farming approach, namely by utilizing organic fertilizers derived from cow manure and additional plant growth-promoting rhizobacteria (PGPR) biological fertilizers. This research was conducted at a production site on Jalan Tidar, Jember, East Java, from January to March 2023. The design used was factorial RAK with 3 repetitions. The first factor was the dose of cow manure, which consists of 4 levels, namely 0, 10, 15, and 20 tons/ha. The second factor was the concentration of PGPR, which consists of 4 levels: 0, 10, 15, and 20 mL/L. The results do not show any interaction between cow manure and PGPR on all parameters. Cow manure has a noticeable effect on growth parameters and quantity. The best dose of cow manure and the highest protein content value was 20 tons/ha. The concentration of PGPR had only a noticeable effect on plant height and number of leaves. PGPR concentrations of 15 mL/L and 20 mL/L both give the best results and produce the highest antioxidant activity value at 15 mL/L.

Keywords: Antioxidant activity, common bean, cow manure, pgpr, protein
Pengendalian Hayati Patogen Fusarium oxysporum f. sp. capsici dengan Isolat Trichoderma sp. Asal Rizosfer Bambu dari Kecamatan Kedu, Kabupaten Temanggung
Authors: Syarifah Sharfina Mutia , Sari Ofivah Permata , Bimantara Arif 
Published: July 2024

Wilt disease caused by Fusarium oxysporum f. sp. Capsici can cause serious problems and reduce red chili yields, so controls are needed that can reduce the development of the pathogen. The purpose of this study was to determine the potential of Trichoderma sp. from the bamboo rhizosphere in Kedu District, Temanggung Regency, in inhibiting the growth of F. oxysporum f. sp. capsici in vitro and in vivo. Trichoderma sp. Was isolated from the rhizosphere of bamboo plants, and F. oxysporum f. sp. capsici was isolated from red chili plants with symptoms of fusarium wilt. Mushroom isolates were purified and identified based on the identification key book. An in vitro test using the double culture method and an in vivo test were conducted in a screen house by applying Trichoderma sp. to the stem of red chili plants. One isolate of Trichoderma sp. was obtained from the soil of the bamboo rhizosphere in the Kedu District, and Fusarium sp. isolates were obtained from the stems of red pepper plants. Based on in vitro antagonist tests, Trichoderma sp. Fungi were able to inhibit the growth of F. Oxysporum f. sp. capsici up to 82.50% at 7 HSI. Trichoderma sp. could inhibit pathogens through antibiotic inhibition mechanisms and competition of nutrients and space to grow. Trichoderma sp. inoculation followed by in vivo inoculation of pathogens on red chili plant stems showed an attack symptom intensity of 4.16% with an antagonistic performance of 75.03% 12 days after inoculation. Trichoderma sp. is effective as an alternative biological control agent for red chili plant disease caused by F. Oxysporum f. sp. capsici.

Keywords: Bamboo Rhizosphere, Fusarium oxysporum f. sp. capsici, Plant Diseases, Trichoderma sp.