bluuebunny/crossref_metadata_2025_split huggingface dataset:
IOLE cooperative learning model in improving students’ collaborative character and reading literacy
Authors: Mardiani Farisa , Rusdarti R. , Purwati Panca Dewi 
Published: July 2024

The character of cooperation and literacy of students today still needs to improve. Effective learning model modifications are required to enhance students' collaborative character and literacy. The purpose of the research is to analyze the effectiveness of the IOLE (inside outside learning) learning model on the character of student collaboration and literacy. The research design used quasi-experimental methods with the control group. For each intervention and control group, research samples of as many as 12 elementary students in grade V. The research was carried out in November 2023 at two elementary schools in the Kudus District. Research instruments use pretests and posttests on the history of cigarettes to evaluate reading literacy. The observation sheet is used to assess the character of cooperation. The study's results showed an influence of the IOLE learning model on collaborative character (p=0,002) and reading literacy (p =0,002) in elementary students. This model can be implemented in primary schools, especially by the teacher of the fifth grade, as a form of learning innovation that can be done to the learning objectives, in particular, the character of cooperation and student reading literacy. AbstrakKarakter kerjasama dan literasi membaca siswa saat ini masih tergolong rendah. Perlu adanya modifikasi model pembelajaran yang efektif untuk meningkatkan karakter kerja sama dan literasi membaca siswa. Tujuan penelitian untuk menganalisis keefektifan model pembelajaran IOLE (inside outside learning) terhadap karakter kerja sama dan literasi membaca siswa. Desain penelitian menggunakan quasi experimental with control group. Sampel penelitian sebanyak 12 siswa SD kelas V untuk masing-masing kelompok intervensi dan kontrol. Penelitian dilakukan pada Bulan November 2023 di 2 SD Negeri di Kabupaten Kudus. Instrumen penelitian menggunakan pretest dan posttest mengenai sejarah rokok kretek untuk menilai literasi membaca. Lembar observasi digunakan untuk menilai karakter kerja sama. Hasil penelitian menunjukkan terdapat pengaruh model pembelajaran IOLE terhadap karakter kerja sama (p=0,002) dan literasi membaca (p=0,002) pada siswa SD. Model pembelajaran IOLE efektif meningkatkan karakter kerja sama dan literasi membaca siswa SD sehingga mendukung capaian tujuan pembelajaran siswa khususnya pada mata pelajaran bahasa Indonesia. Model ini dapat diimplementasikan di sekolah dasar khususnya oleh guru kelas V sebagai bentuk inovasi pembelajaran yang dapat dilakukan untuk mencapai tujuan pembelajaran khususnya karakter kerja sama dan literasi membaca siswa.Kata Kunci: karakter kerjasama; literasi membaca; model pembelajaran IOLE
Model Project Based Learning Kontribusinya terhadap Intensi Kewirausahaan Siswa Pada Materi Sistem Layanan Jasa (Studi Kuasi Eksperimen pada SMKN 3 Cimahi)
Authors: Supardi Endang , Mulyati Sri , Sari Indah Puspita 
Published: July 2024

Intensi Kewirausahaan adalah salah faktor penting yang mempengaruhi individu untuk menjadi seorang wirausaha. Sebagai salah satu faktor sangat berpengaruh, intensi kewirausahaan penting ditingkatkan pada guna menciptakan banyak wirausaha dan menekan angka pengangguran. Salah satu cara untuk meningkatkan intensi kewirausahaan adalah melalui Pendidikan yaitu pada mata pelajaran PKK. Pemilihan model pembelajaran sangat penting dalam melakukan pembelajaran PKK. Artikel ini dalam menyuguhkan pembahasan yang disimpulkan dari penelitian ekpperimen semu dengan dessain NonEquivalent Control Group Design yang ditujukan guna mengetahui pengaruh model Project Based Learning terhadap intensi kewirausahaan siswa pada materi sistem pelayana jasa kelas XI OTKP di sebuah SMK di kota Cimahi. Hasil dari analisis angket intensi kewirausahaan siswa yang diberikan sebagai pre test dan post adalah bahwa skor rata-rata siswa yang menggunakan model PJBL lebih tinggi bila dibandingkan dengan kelas yang tidak dengan PJBL. Perbedaan tersebut juga menggambarkan bahwa PJBL berpengaruh secara signifikan. Bila disimpulkan PJBL mampu meningkatkan Intensi Kewirausahaan pada siswa, oleh karena itu Penerapan PJBL bisa digunakan sebagai pilihan alternatif dalam pembelajaran Kewirausahaan.
An Empirically Constrained Forecasting Strategy for Induced Earthquake Magnitudes Using Extreme Value Theory
Authors: Verdon James P. , Eisner Leo 
Published: July 2024

Abstract
Induced seismicity magnitude models seek to forecast upcoming magnitudes of induced earthquakes during the operation of subsurface industries such as hydraulic fracturing, geothermal stimulation, wastewater disposal (WWD), and carbon capture and storage. Accurate forecasting models could guide operational decision making in real time; for example, operations could be reduced or paused if forecast models indicate that magnitudes may exceed acceptable levels. Robust and transparent testing of forecasting models is required if they are to be adopted by operators and regulators of such industries. We develop and test a suite of models based on extreme value estimators to forecast the magnitudes of upcoming induced seismic events based on observed seismicity. We apply these models to multiple induced seismicity cases from WWD in Oklahoma and in western Texas, as well as other cases of seismicity caused by subsurface fluid injection in North America, Europe, and China. In total, our testing dataset consists of &gt;80 individual sequences of induced seismicity. We find that all the models produce strong correlation between observed and modeled magnitudes, indicating that the forecasting provides useful information about upcoming magnitudes. However, some models are found to systematically overpredict the observed magnitudes, whereas others tend to underpredict. As such, the combined suite of models can be used to define upper and lower estimators for the expected magnitudes of upcoming events, as well as empirically constrained statistical expectations for how these magnitudes will be distributed between the upper and lower values. We conclude by demonstrating how our empirically constrained distribution can be used to produce probabilistic forecasts of upcoming induced earthquake magnitudes, applying this approach to two recent cases of induced seismicity.
The Borrowing and Monitoring Medical Equipment Application in Hospital and Laboratory
Authors: Pradana Yudha 
Published: July 2024

Good management of medical equipment in hospitals is mandatory, with the aim of ensuring that it is always well monitored. The management of this medical equipment is usually done manually by filling in forms and assisted by word and number processing software carried out by electromedical staff. With so many medical devices in hospitals and so few electromedical personnel, plus data collection is still carried out manually, it will not be easy to find information on the management of these devices, and it will take a long time. Research on Borrowing and Monitoring Medical Devices in Hospital and Laboratory Applications is a web application that was built using PHP and XAMPP coding as a database. This application aims to make it easier for users to borrow and monitor medical equipment in hospitals and laboratories. In this application, users can borrow medical equipment online and monitor the condition of the borrowed medical equipment. Apart from that, this application is also equipped with a notification feature to remind users about the due date for returning borrowed medical equipment. Hopefully, this application can increase efficiency and effectiveness in managing medical equipment in hospitals and laboratories.
Perception of ethics committee members and investigators on implementation of e-EC software for ethics committees
Authors: Shetty Yashashri , Marathe Padmaja , Lad Manasi , Auti Prajakta , Katkar Janhavi , Singh Vishal 
Published: July 2024

Background: An e-EC software (Create 4) was introduced since past 4 years at few institutional ethics committees (EC) in India. The software provided facilities for submission, online review and communication between investigator and EC. The study was to assess the perception of different stakeholders: investigators, chairperson, member secretary (MS), EC members, administrative staff regarding their experiences of using software, challenges faced and recommendations for improvisation.
Methods: Following approval of the institutional EC, the participants were enrolled after obtaining their written informed consent. The questionnaires specifically designed and validated for each category of investigators, EC members and administrative staff were administered. Strict confidentiality was maintained. The data was analysed using descriptive statistics.
Results: A total of 64 stakeholders who participated, there were 34 investigators, 18 EC members, 2 Chairpersons, 4 member secretaries, 6 administrative staff. The e-software was accepted well by majority of the stakeholders. Overall, the software was found to be user-friendly. A few challenges faced were: lack of adequate training for investigators and new EC members, inconvenience faced while downloading study documents one by one and the need to ensure uninterrupted internet access at workplace. The user ECs should ensure that the investigators and EC members are tech-savvy and they receive prior training. It was suggested that there needs to be an autofill option built-in while uploading document/s.
Conclusions: E-software was found to be useful by the stakeholders and provided suggestions to optimize its us.
Navigating a paradigm shift; food and drug administration approved Tarlatamab-dlle redefining the landscape of small cell lung cancer therapy
Authors: Gul Muhammad Hamza , Wardak Abdul Baseer , Waheed Aiman 
Published: July 2024

Small cell lung cancer (SCLC) constitutes 10% of lung cancer. It is the leading cause of death due to cancer in men and the second most prevalent cause of cancer related death in women worldwide. It is an extremely hostile tumor with early development, spread, and fatal as it is typically found too late. Early-stage patients are usually treated with chemotherapy and thoracic radiation and surgery is rarely used to treat this malignancy. The addition of immunotherapy to first-line chemotherapy has improved survival for the first time in the decennary. It has demonstrated promise in producing significant, long-lasting responses. The disease is still challenging to treat but adding radiation therapy to a patient's care at certain intervals may enhance illness control. Platinum-based chemotherapy is initially quite effective, eliciting prompt and often substantial responses, however, they are transient effects, and when SCLC recurs, treatment resistance is strong.
Research Progress on Chemical Ecological Management of Three Tomicus Species (Coleoptera: Scolytidae) in Yunnan Province of China1
Authors: Wang Junhui , Gao Weizhong , Cai Hongzhen , Teng Jun 
Published: July 2024

Abstract
Bark beetles in the genus Tomicus (Latreille) (Coleoptera: Scolytidae) are the most destructive pests of pine trees (Pinaceae) in the Yunnan region of China, causing significant damage to shoots and trunks, leading to extensive pine tree mortality. This has had a negative impact on the sustainabilityequally and healthy development of local forestry. Currently, the primary methods of managing Tomicus are through the removal of damaged wood and chemical control, which not only requires significant manpower, materials, and financial resources, but also poses a threat to the ecological stability of the environment and has led to the development of resistance to pesticides by the pests. This article introduces an overview of research in the field of chemical ecological management of Tomicus minor (Hartig), T. yunnanensis Kirkendall & Faccoli, and T. brevipilosus (Eggers) in Yunnan Province. This includes summaries of research on informational chemicals, artificial attractants, and volatiles from both host and nonhost plants. The aim of this review is to provide a comprehensive overview of chemical ecological management methods for these beetles, thus assisting researchers and research institutions in their efforts to provide for sustainability of our environmental resources.
Long-term prognosis of life in patients with cerebrovascular accident: the role of diabetes mellitus (according to the REGION-M registry outpatient follow-up phase)
Authors: Voronina V. P. , Zagrebelny A. V. , Lukina Yu. V. , Tolpygina S. N. , Kutishenko N. P. , Chernysheva M. I. , Lukyanov M. M. , Dmitrieva N. A. , Lerman O. V. , Martsevich S. Yu. , Drapkina O. M. 
Published: July 2024

Aim. To study the long-term prognosis of patients’ life who have suffered cerebrovascular accident (CVA), and to determine the role of diabetes mellitus (DM) as a possible negative prognostic factor, according to the outpatient follow-up stage in the REGION-M registry.Material and methods. The outpatient part of the REGION-M registry included 684 patients assigned to the Moscow City Polyclinic No. 64, discharged from the hospital in the period from 01.01.2012 to 30.04.2017 with a confirmed diagnosis of CVA, of which 122 patients (17.8%) were diagnosed with DM. The polyclinic stage included three observation points: 2017, 2020, and 2022. Data on the life status of all patients were obtained by telephone survey, if it was impossible to establish contact with the patient or his relatives, a unified medical information and analytical system was used to determine the life status of patients. The study patients were observed on an outpatient basis for more than 5 years (ME 1958 (751; 2555) days), the primary endpoint was death from any cause.Results. Information about the life status was obtained for all 684 patients. By the end of the observation, 415 cohort members had died, and 269 were alive. The average age of patients with DM was significantly higher than that of patients without DM: 71.5±10.9 years vs 68.0±14.7 years (p<0.05). The proportion of women in the cohort of DM patients was significantly higher than in the cohort of patients without DM: 72.1% vs 55.2% (p<0.05). Patients with DM were statistically significantly more likely to have a history of comorbid diseases (coronary heart disease, myocardial infarction, arterial hypertension, kidney disease and chronic lung disease, chronic heart failure). Obesity occurs with the same frequency in patients with and without DM. The studied groups of patients did not differ in types of CVA (transient ischemic attack, ischemic, hemorrhagic stroke). According to Cox Proportional Hazards Regression Analysis at the outpatient stage of follow-up, no significant negative effect of DM on patients’ mortality with CVA was confirmed (relative risk =1.239 (95% CI: 0.975; 1.574), p=0.079).Conclusion. In the long-term follow-up of patients with CVA, there was no statistically significant adverse effect of DM on long-term survival.
Use of glycoprotein IIb/IIIa inhibitors in myocardial infarction in the Russian Federation, according to the Russian Registry of Acute Myocardial Infarction REGION-IM
Authors: Kostritca N. S. , Rabinovich R. M. , Shakhnovich R. M. , Yavelov I. S. , Gulyan R. G. , Rytova Yu. K. , Tereschenko S. N. , Erlikh A. D. , Pevzner D. V. 
Published: July 2024

Aim. To analyze the frequency, indications, and outcomes of using glycoprotein IIb/IIIa inhibitors in patients with acute myocardial infarction (AMI) in Russia based on data from a multicenter registry.Material and methods. This work is part of the REGION-MI (Russian Registry of Acute Myocardial Infarction) multicenter retrospective-prospective observational study, which included patients admitted to hospitals in 45 regions of Russia with a diagnosis of AMI from 2020 to 2023. The decision to prescribe glycoprotein IIb/IIIa inhibitors was made by physicians. The observation period was 12 months, the following outcomes were recorded: cardiovascular events (relapse/repeated AMI, stent thrombosis, revascularisation), hemorrhagic complications, and in-hospital and all-cause mortality during the entire observation period. The study is conducted on the "Quinta" platform. Statistical data processing was performed using IBM SPSS Statistics ver.24.Results. A total of 10,884 patients were included in the registry, glycoprotein IIb/IIIa inhibitors were prescribed to 114 patients (1%), all of whom underwent percutaneous coronary intervention (PCI), while among patients with non-ST elevation myocardial infarction, the frequency of IIb/IIIa inhibitors was 0.5%, among ST-segment elevation myocardial infarction patients — 1.3%. Eptifibatide was used most often (67.5%), tirofiban was prescribed in 28.9% of cases, abciximab — 2.6%, framon — 0.9%. The most common indication for prescribing drugs were complications of PCI, in particular — distal embolism. There was a higher incidence of cardiogenic shock and multivessel revascularization in the glycoprotein IIb/IIIa inhibitor group. In-hospital mortality and adverse events within 180 days (death, cardiovascular events) did not differ between patients who did and did not receive glycoprotein IIb/IIIa inhibitors. The use of glycoprotein IIb/IIIa inhibitors in this study was associated with an increased risk of all in-hospital bleeding (odds ratio 9.656, confidence interval 2.859-3,894, p <0.001). Other predictors of in-hospital bleeding were: prescription of glycoprotein IIb/IIIa inhibitors, chronic kidney disease with glomerular filtration rate <60 ml/min/1.73 m2, body weight less than 60 kg.Conclusion. We observed a very low frequency of glycoprotein IIb/IIIa inhibitors usage in Russia, while these drugs are used mainly for complications of PCI in the group of patients with the highest risk — with cardiogenic shock, multivessel revascularisation, and complications of the procedure, which can have impact on the outcomes. Further research is needed to develop an optimal protocol for glycoprotein IIb/IIIa inhibitors administration in AMI.
Breast arterial calcification and carotid arteries atherosclerotic load in women
Authors: Kim I. V. , Bochkareva E. V. , Butina E. K. , Molchanova O. V. , Filichkina E. M. , Yarovaya E. B. , Drapkina O. M. 
Published: July 2024

Aim. To develop a diagnostic complex (DC) of ultrasound markers characterizing carotid arteries (CA) atherosclerotic load, and to evaluate its association with breast arterial calcification (BAC) in women.Material and methods. The cross-sectional case-control study included 198 women aged 40-74 years, who made up of 2 groups of 99 participates in each, with or without BAC, who underwent diagnostic digital mammography. The study protocol included physical examination, medical history, questionnaires, laboratory tests, electrocardiography, carotid ultrasound. BAC severity was assessed on a 12-point scale. Ultrasound parameters of CA atherosclerotic load were assessed: the number of atherosclerotic plaques, maximum, total and average stenosis. All patients signed informed consent to participate in the study.Results. Atherosclerotic plaques were detected in 79.9% of women with BAC and in 60.6% of women without BAC. The best statistically significant difference in both groups was found in the "number of atherosclerotic plaques", "average stenosis" and "maximum stenosis", on the basis of which the DC in points was formed. When comparing the average DC value, it was found that the degree of atherosclerotic load is statistically significantly higher in women with calcification (p=0.001). There was a significantly higher proportion of people with BAC in the groups of women with both DC values >2 points (p<0.001) and DC >0 points (p=0.022). Univariate analysis showed that with a DC >2 points, the probability of having BAC in women increases by 4.06 times (95% CI: 1.92-9.25; p<0.001). Menopause (p=0.024), osteoporosis (p=0.013), glomerular filtration rate <90 ml/min/1.73 m2 (p=0.004), thyroid disease (p=0.041) and hormone replacement therapy for hypothyroidism (p=0.015) were associated with BAC. As a result of multivariate analysis, significant associations of BAC with DC >2 points (OR=2.87; p=0.012) and hormone replacement therapy for hypothyroidism (OR=0.31; p=0.017) were found. There was no statistically significant relationship between DC and the severity of BAC on a 12-point scale.Conclusion. A DC was developed to assess the degree of CA atherosclerotic load. Differences in DC parameters were revealed between groups of women with and without BAC: DC>2 points increase the chance of having BAC. The demonstrated connection between BAC and asymptomatic CA atherosclerosis indicates the prospects for using this form of vascular calcification as a gender-specific marker of cardiovascular diseases in women.
Evaluation of the Specific Growth Rate to Predict the Biogas Production Process in a Mini-Biodigester
Authors: Bagaya Noufou , Koumbem Windé Nongué Daniel , Baldé Younoussa Moussa , Diop Sette , Ouédraogo Issaka , Korgo Bruno , Kam Sié 
Published: July 2024

In this work, we are interested in the mathematical analysis of the model of a bioreactor based on the results of a model already implemented in ADM1. The study is based on the expectations of Burkinabè households with biodigesters of 4m<sup>3</sup>, 6 m<sup>3</sup>, 8 m<sup>3 </sup>or more in terms of biogas production capacity. It is an observability analysis and estimation scheme for specific growth rates for an anaerobic digestion (AD) process of cow dung. A 1<em>- stage</em> model of 3 dynamic states is assumed describing all anaerobic digestion with a different population of microorganisms, and the evaluation of biogas production (methane + carbon dioxide). The result of specific growth rates (<em>µ<sub>max </sub>= 0.44d<sup>-1</sup></em>) of bacterial populations' concentration (24<em>gL<sup>-1</sup></em> ± 2.3%) and substrate concentration (<em>6.5gL<sup>-1</sup>± 0.5%) </em>are estimated from the dilution rate and biogas. Thus, biogas production ranges from 0 to 3.5<em> m</em><sup>3</sup><em> </em>per day, more than sufficient for three daily meals for a 4-person household. Overall, the dynamics of anaerobic digestion appear to depend on the type of organic matter contained in cow substrates.