bluuebunny/crossref_metadata_2025_split huggingface dataset:
Morphological and clinical risk factors for posterior communicating artery aneurysm rupture
Authors: Matsukawa Hidetoshi , Fujii Motoharu , Akaike Gensuke , Uemura Akihiro , Takahashi Osamu , Niimi Yasunari , Shinoda Masaki 
Published: October 2013

Object
Recent studies have shown that posterior circulation aneurysms, specifically posterior communicating artery (PCoA) aneurysms, are more likely to rupture than other aneurysms. To date, few studies have investigated the factors contributing to PCoA aneurysm rupture. The authors aimed to identify morphological and clinical characteristics predisposing to PCoA aneurysm rupture.

Methods
The authors retrospectively reviewed 134 consecutive patients with PCoA aneurysms managed at their facility between July 2003 and December 2012. The authors divided patients into groups of those with aneurysmal rupture (n = 39) and without aneurysmal rupture (n = 95) and compared morphological and clinical characteristics. Morphological characteristics were mainly evaluated by 3D CT angiography and included diameter of arteries (anterior cerebral artery, middle cerebral artery, and internal carotid artery), size of the aneurysm, dome-to-neck ratio, neck direction of the aneurysmal dome around the PCoA (medial, lateral, superior, inferior, and posterior), aneurysm bleb formation, whether the PCoA was fetal type, and the existence of other intracranial unruptured aneurysm(s).

Results
Patients with ruptured PCoA aneurysms were significantly younger (a higher proportion were < 60 years of age) and a significantly higher proportion of patients with ruptured PCoA aneurysms showed a lateral direction of the aneurysmal dome around the PCoA, had bleb formation, and the aneurysm was > 7 mm in diameter and/or the dome-to-neck ratio was > 2.0. Multivariate logistic regression analysis showed age < 60 years (OR 4.3, p = 0.011), history of hypertension (OR 5.1, p = 0.008), lateral direction of the aneurysmal dome around the PCoA (OR 6.7, p = 0.0001), and bleb formation (OR 11, p < 0.0001) to be significantly associated with PCoA aneurysm rupture.

Conclusions
The present results demonstrated that lateral projection of a PCoA aneurysm may be related to rupture.
Gene flow and genetic diversity in cultivated and wild cacao (Theobroma cacao) in Bolivia
Authors: Chumacero de Schawe Claudia , Durka Walter , Tscharntke Teja , Hensen Isabell , Kessler Michael 
Published: October 2013

•Premise of the study:The role of pollen flow within and between cultivated and wild tropical crop species is little known. To study the pollen flow of cacao, we estimated the degree of self‐pollination and pollen dispersal distances as well as gene flow between wild and cultivated cacao (Theobroma cacaoL.).•Methods:We studied pollen flow and genetic diversity of cultivated and wild cacao populations by genotyping 143 wild and 86 cultivated mature plants and 374 seedlings raised from 19 wild and 25 cultivated trees at nine microsatellite loci.•Key results:A principal component analysis distinguished wild and cultivated cacao trees, supporting the notion that Bolivia harbors truly wild cacao populations. Cultivated cacao had a higher level of genetic diversity than wild cacao, presumably reflecting the varied origin of cultivated plants. Both cacao types had high outcrossing rates, but the paternity analysis revealed 7–14% self‐pollination in wild and cultivated cacao. Despite the tiny size of the pollinators, pollen was transported distances up to 3 km; wild cacao showed longer distances (mean = 922 m) than cultivated cacao (826 m). Our data revealed that 16–20% of pollination events occurred between cultivated and wild populations.•Conclusions:We found evidence of self‐pollination in both wild and cultivated cacao. Pollination distances are larger than those typically reported in tropical understory tree species. The relatively high pollen exchange from cultivated to wild cacao compromises genetic identity of wild populations, calling for the protection of extensive natural forest tracts to protect wild cacao in Bolivia.
Prendre une voix dans ses bras
Authors: Prat Régine 
Published: October 2013

La voix, empreinte de la personnalité, est au cœur de la communication ; elle représente le corps du verbe, porte les aspects non verbaux de la communication et transmet les émotions. Elle est, selon l’auteur, indissolublement liée au toucher et à la première expérience du monde dès la vie intra-utérine, organisée par le rythme du touché/lâché. Ces hypothèses psychanalytiques seront confrontées aux données récentes de la recherche en neurosciences, en sciences du langage et en psychologie développementale.
Comment la voix vient-elle aux enfants ?
Authors: Vivès Jean-Michel 
Published: October 2013

La voix occupe, parmi les objets pulsionnels, une place particulière en ce qu’elle participe, en étant le vecteur de la parole, à la naissance même du sujet. L’auteur de cet article s’attache à montrer comment la voix vient aux enfants : donnée par l’Autre, dans une improvisation, la voix doit être à la fois accueillie et oubliée. L’infans, pour pouvoir acquérir une voix, doit résonner à celle de l’Autre qui l’invite à devenir, et dans le même temps, se rendre sourd, en constituant ce que l’auteur choisit d’appeler un point sourd, à l’appel à venir se perdre que cette même voix lui adresse.
Actions intergénérationnelles et développement durable en milieu rural
Authors: Attias-Donfut Claudine 
Published: October 2013

Cet article propose d’examiner la signification des actions intergénérationnelles et de ses enjeux dans les territoires à dominance rurale, dont la spécificité est analysée dans deux directions, d’une part leur insertion dans les nouvelles formes de sociabilités extra-urbaines et d’autre part leur contribution aux particularités du développement durable local, en référence à l’Approche par les Capacités (AC) initiée par A. Sen. La nécessité d’assurer une équité dans les capacités intergénérationnelles passe par l’amélioration de la transmission, qui est un des principaux objectifs de l’intergénération et qui est sous-jacent à tous ses programmes. La réussite de ces actions appelle à la fois un dynamisme « associationniste » et un changement du regard sur le vieillissement des espaces ruraux, pour transformer en atout ce qui est trop souvent perçu uniquement comme un problème.
Identités professionnelles à l'épreuve de la ruralité : adaptations, renouvellement...?
Authors: Salles Mylène 
Published: October 2013

Comment la ruralité peut-elle marquer l’identité des professionnels de l’aide à la personne ? Nous avons revisité deux enquêtes qualitatives menées en milieu rural. Sans en douter, l’histoire partagée et l’interconnaissance se juxtaposent à l’identité professionnelle. Cette unicité est remise en question par les espaces d’exercice. En établissement ou à domicile, la ruralité impose des variations à l’identité professionnelle.
The Role of Radiotherapy in Bladder Cancer
Authors: Pinnarò Paola , Giordano Carolina , Giovinazzo Giuseppe , Saracino Biancamaria 
Published: October 2013

In this article we report on the current role of radiotherapy in the management of non-muscle invasive as well as in muscle invasive bladder cancer. Radiotherapy seems to have no role in non-muscle invasive bladder cancer. In muscle invasive bladder tumors, the role of radiotherapy is under investigation in view of new radiotherapy techniques and novel cytotoxic and biological agents.
Decellularized Feeders: An Optimized Method for Culturing Pluripotent Cells
Authors: Lim Mei Ling , Jungebluth Philipp , Sjöqvist Sebastian , Nikdin Hero , Kjartansdóttir Kristín Rós , Unger Christian , Vassliev Ivan , Macchiarini Paolo 
Published: October 2013

Abstract
Pluripotent cells such as human embryonic stem cells and human induced pluripotent stem cells are useful in the field of regenerative medicine because they can proliferate indefinitely and differentiate into all cell types. However, a limiting factor for maintaining and propagating stem cells is the need for inactivated fibroblasts as a growth matrix, since these may potentially cause cross-contamination. In this study, we aimed to maintain stem cells on the extracellular matrix (ECM) of either nonirradiated or γ-irradiated fibroblasts. It has been demonstrated that the ECM contains factors and proteins vital for the adhesion, proliferation, and differentiation of pluripotent cells. In order to preserve the ECM, the cell layers of the fibroblasts were decellularized by treatment with 0.05% sodium dodecyl sulfate (SDS), which resulted in an absence of DNA as compared with conventional feeder culture. However, SDS treatment did not cause a detectable change in the ECM architecture and integrity. Furthermore, immunohistochemistry demonstrated that expressions of major ECM proteins, such as fibronectin, collagen, and laminin, remained unaltered. The human pluripotent cells cultured on this decellularized matrix maintained gene expression of the pluripotency markers NANOG and OCT4 and had the potency to differentiate to three germ layers. The in vitro culture system shown here has an excellent potential since the main allogeneic components (i.e., DNA of the feeder cells) are removed. It is also a technically easy, fast, safe, and cheap method for maintaining a refined feeder-free stem cell culture for further cell differentiation studies.
À l’avant-garde du folklore : Édouard-Zotique Massicotte, 1882-1915
Authors: Joly Diane 
Published: October 2013

Quelle place occupe Édouard-Zotique Massicotte dansl’historiographie de l’ethnologie ? Cette étudeprésente ses intérêts, ses recherches et sonparcours littéraire entre 1882 et 1915, soit avant sa rencontreavec Marius Barbeau en 1917. Son oeuvre pionnière dans ledomaine du folklore est souvent citée. Mais, elle reste peuconnue des chercheurs. L’analyse du discours abordé sousl’angle de l’agitateur culturel met en lumière savolonté de partager ses connaissances au-delà de sespairs, et ses exhortations à poursuivre les recherches. Dansl’ensemble, la contribution de Massicotte à la disciplinede l’ethnologie – le folklore à son époque–, et à l’émergence du patrimoine serévèle plus riche qu’anticipé.
La chasse aux lutins. Chronique d’une tradition réinventée
Authors: Bergeron Bertrand 
Published: October 2013

À l’automne 2007 au Lac-Saint-Jean, l’initiative d’un grand-père (Régis Tremblay) à l’endroit de ses deux petits-fils (Maxime et Alexis) a déclenché une véritable déferlante qui s’est répandue d’abord aux villages circonvoisins avant de déborder dans les autres régions du Québec, puis dans certaines provinces canadiennes à partir de son lieu d’origine : Lac-à-la-Croix−Métabetchouan. Il s’agit de la chasse aux lutins. De manière spontanée, Régis Tremblay s’est approprié une ancienne croyance et l’a réinventée pour satisfaire l’imaginaire des enfants, avides de merveilleux. Cet article se propose de remonter à la genèse de ce phénomène qui prend de l’ampleur afin d’en comprendre à la fois la contagion qu’il a engendrée auprès des enfants, contagion qui a fini par emporter l’adhésion de leurs parents, et les enjeux ludiques et sociaux impliqués par sa propagation.
La production littéraire de la barbarie
Authors: Citton Yves 
Published: October 2013

Et Laurent Bordelon (1653-1730) et le protagoniste de son Histoire des imaginations extravagantes de Monsieur Oufle (1710) occupent chacun une position d’excentrique au sein de notre histoire littéraire. Cette double marginalité nous invite à revisiter l’articulation entre littérature et barbarie. Le personnage donne l’exemple d’une barbarie à la fois érudite et bestiale, au terme de laquelle la littérature peut faire de l’homme un loup-garou pour l’homme. L’auteur dénonce cette barbarie en s’exilant des conventions littéraires, en se faisant lui-même un barbare incapable de parler la langue commune du récit. L’analyse détaillée d’un épisode de cet antiroman pose non seulement la question de savoir comment on peut devenir loup-garou, alors même que nous savons que les loups-garous n’existent pas. Elle nous pousse surtout à nous demander ce que c’est qu’un « esprit », aussi bien à l’échelle de l’individu qu’à celle du public. On en conclut que l’esprit relève non d’une psychologie, mais d’une médiologie : l’antiroman de Monsieur Oufle nous aide à voir que notre esprit consiste en une circulation médiatique, et que la littérature, telle qu’elle a pris sa forme moderne un siècle après la parution de ce texte, n’a fait qu’approfondir le besoin obstiné qu’éprouvait Bordelon de résister à cette circulation en l’évidant de toute crédibilité.
Comparative Effectiveness of Three Digital Interventions for Adults Seeking Psychiatric Services
Authors: Horwitz Adam G. , Mills Elizabeth D. , Sen Srijan , Bohnert Amy S. B. 
Published: July 2024

ImportanceThere is a substantial gap between demand for and availability of mental health services. Digital mental health interventions (DMHIs) are promising tools for bridging this gap, yet little is known about their comparative effectiveness.ObjectiveTo assess whether patients randomized to a cognitive behavioral therapy (CBT)–based or mindfulness-based DMHI had greater improvements in mental health symptoms than patients randomized to the enhanced personalized feedback (EPF)–only DMHI.DESIGN,SETTING, AND PARTICIPANTS This randomized clinical trial was conducted between May 13, 2020, and December 12, 2022, with follow-up at 6 weeks. Adult patients of outpatient psychiatry services across various clinics within the University of Michigan Health System with a scheduled or recent outpatient psychiatry appointment were recruited. Eligible patients were randomized to an intervention arm. All analyses followed the intent-to-treat principle.InterventionsParticipants were randomized to 1 of 5 intervention arms: (1) EPF only; (2) Silvercloud only, a mobile application designed to deliver CBT strategies; (3) Silvercloud plus EPF; (4) Headspace only, a mobile application designed to train users in mindfulness practices; and (5) Headspace plus EPF.Main Outcomes and MeasuresThe primary outcome was change in depressive symptoms as measured by the Patient Health Questionnaire-9 (PHQ-9; score range: 0-27, with higher scores indicating greater depression symptoms). Secondary outcomes included changes in anxiety, suicidality, and substance use symptoms.ResultsA total of 2079 participants (mean [SD] age, 36.8 [14.3] years; 1423 self-identified as women [68.4%]) completed the baseline survey. The baseline mean (SD) PHQ-9 score was 12.7 (6.4) and significantly decreased for all 5 intervention arms at 6 weeks (from −2.1 [95% CI, −2.6 to −1.7] to −2.9 [95% CI, −3.4 to −2.4]; n = 1885). The magnitude of change was not significantly different across the 5 arms (F4,1879 = 1.19; P = .31). Additionally, the groups did not differ in decrease in anxiety or substance use symptoms. However, the Headspace arms reported significantly greater improvements on a suicidality measure subscale compared with the Silvercloud arms (mean difference in mean change = 0.63; 95% CI, 0.20-1.06; P = .004).Conclusions and RelevanceThis randomized clinical trial found decreases in depression and anxiety symptoms across all DMHIs and minimal evidence that specific applications were better than others. The findings suggest that DMHIs may provide support for patients during waiting list–related delays in care.Trial RegistrationClinicalTrials.gov Identifier: NCT04342494
kV reference dosimetry in Australia and New Zealand: Survey results and trends
Authors: Tyler Madelaine , Duncan Mitchell , McNamara Joanne 
Published: July 2024

AbstractPurposeTo assess the number of radiotherapy kilovoltage (kV) units in service, their clinical utilization, and methodology and equipment used for absorbed dose determination across Australia and New Zealand.MethodsA survey was sent to 61 Australian and New Zealand radiotherapy providers in the second half of 2023.ResultsFifty‐seven responses were received, with 43 departments having kV units and providing beam quality data for 185 therapeutic kV beams 20–300 kVp. Percentage depth dose curves were compared between five clinical beams with 100 kVp and 2.13–6.28 mm Aluminum half value layers (HVLs), demonstrating large differences that can occur between beams with the same kVp. Eighteen departments provided clinical utilization data for their kV units, with a total of 4458 treatment courses and their corresponding kVp reported. All departments complied with national and international recommendations with respect to the equipment used for reference dosimetry of kV beams; 77% of ionization chambers used for absorbed dose determination were of Farmer‐type, with the remaining 23% being plane parallel soft x‐ray chambers. Methods of derivation of air‐kerma calibration factors varied, with 73% of respondents using a draft document disseminated by the Australian Primary Standards laboratory, 23% using HVL alone, and 6% using other methods.ConclusionsThe results of this survey provide a snapshot of kilovoltage radiation therapy use and the number of kV units across Australia and New Zealand. This data can be used as a point of reference for future investigations into clinical utilization and reference dosimetry methods across Australia and New Zealand or for comparisons with other countries, facilitating standardization of reference dosimetry practice for kilovoltage units.
Validation of Acuros for total body irradiation at extended distance
Authors: Nelson Geoffrey , Sarkar Vikren , Szegedi Martin , Molineu Andrea , Olch Arthur J. , Kunz Jeremy N. , Zhao Hui , Huang Y. Jessica , Pillai Susha , Rassiah Prema 
Published: July 2024

AbstractPurposeStandardized and accurately reported doses are essential in conventional total body irradiation (TBI), especially lung doses. This study evaluates the accuracy of the Acuros algorithm in predicting doses for extended‐distance TBI.MethodsMeasurements and calculations were done with both 6 and 18 MV. Tissue Maximum Ratio (TMR), output and off axis ratios (OAR) were measured at 200 and 500 cm source to detector distance and compared to Acuros calculated values. Two end‐to‐end tests were carried out, one with an in‐house phantom (solid water and Styrofoam) with inserted ion chambers and the other was with the Imaging and Radiation Oncology Core (IROC) TBI anthropomorphic phantom equipped with TLDs. The end‐to‐end test was done for 6 and 18 MV both with and without lung blocks. The source to midplane distance for both phantoms were at 518 and 508 cm respectively. Lung blocks were placed at the phantom surface and a beam spoiler was positioned 30 cm from the surface of the phantoms as per our clinical set up.ResultsThe agreement between measured and calculated TMR, output and off axis ratios for both 6 and 18 MV were within 2%. Ion chamber measurements in both the Styrofoam and solid water for both energies carried out with and without lung blocks were within 2% of calculated values. TLD measured doses for both 6 and 18 MV in the IROC phantom were within 5% of calculated doses which is within the uncertainty of the TLD measurement.ConclusionsThe results indicate that the clinical beam model for Acuros 16.1 commissioned at standard clinical distances is capable of calculating doses accurately at extended distances up to 500 cm.
Event boundary perception in audio described films by people without sight
Authors: Johansson Roger , Rastegar Tina , Lyberg‐Åhlander Viveka , Holsanova Jana 
Published: July 2024

AbstractAudio description (AD) plays a crucial role in making audiovisual media accessible to people with a visual impairment, enhancing their experience and understanding. This study employs an event segmentation task to examine how people without sight perceive and segment narrative events in films with AD, compared to sighted viewers without AD. Two AD versions were utilized, differing in the explicitness of conveyed event boundaries. Results reveal that the participants without sight generally perceived event boundaries similarly to their sighted peers, affirming AD's effectiveness in conveying event structures. However, when key event boundaries were more implicitly expressed, event boundary recognition diminished. Collectively, these findings offer valuable insights into event segmentation processes across sensory modalities. Additionally, they underscore the significance of how AD presents event boundaries, influencing the perception and interpretation of audiovisual media for people with a visual impairment and providing applied insights into event segmentation, multimodal processing, and audiovisual accessibility.
Prospects and Challenges of Practical Nonaqueous Potassium‐Ion Batteries
Authors: Wang Linlin , Zhang Shiwan , Li Nan , Chen Jiale , Chen Yifan , Zhang Zhe , Tan Lulu , Niu Xiaogang , Yang Yusi , Zhang Jianwen , Li Hongliang , Ji Xiao , Zhu Yujie 
Published: July 2024

AbstractOver the past decade, concerns over the sustainability of lithium‐ion batteries (LIBs) have arisen due to the scarcity of critical elements such as lithium (Li), nickel (Ni), and cobalt (Co), prompting the exploration of alternative and complementary electrochemical energy storage technologies. Due to the more abundant resources compared to contemporary LIBs and the potentially higher specific energy than the emerging sodium‐ion batteries (SIBs), potassium‐ion batteries (PIBs) have attracted intensive research interest as a promising alternative to existing technologies. Nevertheless, the development of practical PIBs remains in its infancy. In this perspective, the various electrode materials and electrolytes reported for PIBs from an application point of view and identifying the most promising ones with high practical interest are first concisely discussed. Then, the pack‐level specific energy, energy density, and cost analyses are presented for several PIBs chemistries, which are also compared with representative LIBs and SIBs to demonstrate the advantages of PIBs. After that, a succinct discussion is presented to evaluate the practicality of potassium metal batteries. Finally, the challenges associated with the commercialization of PIBs, providing future critical research fronts for the development of practical high‐performance PIBs are outlined.
Rational Design of Fluorinated 2D Polymer Film Based on Donor–Accepter Architecture toward Multilevel Memory Device for Neuromorphic Computing
Authors: Liu Lei , Ji Wenyan , He Weixin , Cheng Yuanzhe , Hao Ruisha , Hao Pengyuan , Dong Huanli , Ding Xuesong , Lei Shengbin , Han Baohang , Hu Wenping 
Published: July 2024

AbstractFluorine‐containing 2D polymer (F‐2DP) film is a desired system to regulate the charge transport in organic electronics but rather rarely reports due to the limited fluorine‐containing building blocks and difficulties in synthesis. Herein, a novel polar molecule with antiparallel columnar stacking is synthesized and further embedded into an F‐2DP system to control over the crystallinity of F‐2DP film through self‐complementary π‐electronic forces. The donor–accepter–accepter′–donor′ (D–A–A′–D′) structure regulates the charge transportation efficiently, inducing multilevel memory behavior through stepwise charge capture and transfer processes. Thus, the device exhibits ternary memory behavior with low threshold voltage (Vth1 of 1.1 V, Vth2 of 2.0 V), clearly distinguishable resistance states (1:102:104) and ternary yield (83%). Furthermore, the stepwise formation of the charge complex endows the device with a wider range to regulate the conductive state, which allows its application in brain‐inspired neuromorphic computing. Modified National Institute of Standards and Technology recognition can reach an accuracy of 86%, showing great potential in neuromorphic computing applications in the post‐Moore era.