bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mission as local economic development in the City of Tshwane: Towards fostering a grass roots, ‘glocal’ alternative vision, with specific reference to Luke 16:19–31
Authors: Mangayi Lukwikilu C. 
Published: November 2014

This article analyses and reflects missiologically on the City of Tshwane’s economy, in terms of its priorities and strategies. It points out that it is to the detriment of local communities that Tshwane’s economy has become a replica of the national economy which is essentially growth-focused and structured to service the global market. It also discusses possibilities for the urban church to be involved in addressing this situation as it wrestles with the question: What role can the church play towards fostering a grass roots, ‘glocal’ alternative vision to the current local economic system? Responding to this question, this article argues that the church, drawing from theological/missiological resources and hermeneutic insights on biblical texts, such as Luke 16:19–31, and on the concept of God’s economy, can steer such an alternative vision for the economy of the City of Tshwane. It ends by demonstrating how the church can engage the issues of local economic development in a practical way, which will lead to an alternative reality where shared prosperity and inclusion are attained.
Towards a fusion of horizons: Thematic contours for an urban public theological praxis-agenda in South Africa
Authors: De Beer Stephan , Swart Ignatius 
Published: November 2014

This article proposes a ‘fusion of horizons’ in constructing urban public theologies in South Africa. This is done through the introduction of five interrelated themes that have emerged from the on-going knowledge and idea production by a distinguishable counterpoint in contemporary scholarly, intellectual and activist engagement with the urban, in the authors’ own South African context but also wider internationally. In advancing a praxis-agenda for urban public theology, the authors subsequently identify the following, albeit not exhaustive, themes: southern urbanisms and the factor of unprecedented urban migration; ‘right to the city’ and urbanisation from below; a reclaiming of the commons; the making of ‘good cities’; and actors of faith in relation to urban social life.
Exact Solutions of Electro-Osmotic Flow of Generalized Second-Grade Fluid with Fractional Derivative in a Straight Pipe of Circular Cross Section
Authors: Wang Shaowei , Zhao Moli , Li Xicheng , Chen Xi , Ge Yanhui 
Published: November 2014

Abstract
The transient electro-osmotic flow of generalized second-grade fluid with fractional derivative in a narrow capillary tube is examined. With the help of the integral transform method, analytical expressions are derived for the electric potential and transient velocity profile by solving the linearized Poisson-Boltzmann equation and the Navier-Stokes equation. It was shown that the distribution and establishment of the velocity consists of two parts, the steady part and the unsteady one. The effects of retardation time, fractional derivative parameter, and the Debye-Hückel parameter on the generation of flow are shown graphically.
Intense Isolated Ultrashort Attosecond Pulse Generation in a Multi-Cycle Three-Colour Laser Field
Authors: Zhang Gang-Tai 
Published: November 2014

Abstract
An efficient method for generating an intense isolated ultrashort attosecond pulse is presented theoretically. By adding a 267 nm controlling pulse to a multi-cycle two-colour field, not only the spectral cutoff and the yields of the harmonic spectrum are evidently enhanced, but also the selection of the single quantum path is realised. Then a high-efficiency supercontinuum with a 504 eV bandwidth and smooth structure is obtained, which enables the production of an intense isolated 30 as pulse. In addition, the influences of the laser parameters on the supercontinuum and isolated attosecond pulse are investigated.
Bone Marrow Regeneration Promoted by Biophysically Sorted Osteoprogenitors From Mesenchymal Stromal Cells
Authors: Poon Zhiyong , Lee Wong Cheng , Guan Guofeng , Nyan Lin Myint , Lim Chwee Teck , Han Jongyoon , Van Vliet Krystyn J. 
Published: November 2014

Abstract
Human tissue repair deficiencies can be supplemented through strategies to isolate, expand in vitro, and reimplant regenerative cells that supplant damaged cells or stimulate endogenous repair mechanisms. Bone marrow-derived mesenchymal stromal cells (MSCs), a subset of which is described as mesenchymal stem cells, are leading candidates for cell-mediated bone repair and wound healing, with hundreds of ongoing clinical trials worldwide. An outstanding key challenge for successful clinical translation of MSCs is the capacity to produce large quantities of cells in vitro with uniform and relevant therapeutic properties. By leveraging biophysical traits of MSC subpopulations and label-free microfluidic cell sorting, we hypothesized and experimentally verified that MSCs of large diameter within expanded MSC cultures were osteoprogenitors that exhibited significantly greater efficacy over other MSC subpopulations in bone marrow repair. Systemic administration of osteoprogenitor MSCs significantly improved survival rates (&gt;80%) as compared with other MSC subpopulations (0%) for preclinical murine bone marrow injury models. Osteoprogenitor MSCs also exerted potent therapeutic effects as “cell factories” that secreted high levels of regenerative factors such as interleukin-6 (IL-6), interleukin-8 (IL-8), vascular endothelial growth factor A, bone morphogenetic protein 2, epidermal growth factor, fibroblast growth factor 1, and angiopoietin-1; this resulted in increased cell proliferation, vessel formation, and reduced apoptosis in bone marrow. This MSC subpopulation mediated rescue of damaged marrow tissue via restoration of the hematopoiesis-supporting stroma, as well as subsequent hematopoiesis. Together, the capabilities described herein for label-freeisolation of regenerative osteoprogenitor MSCs can markedly improve the efficacy of MSC-based therapies.
Le rat est mort ! Ou le jeu de la tradition dans l’Hamlet de William Shakespeare (Notes de mise en scène)
Authors: Iovita Cristina 
Published: November 2014

L’article décrit le processus de création du spectacle Hamlet de William Shakespeare adapté et mis en scène par Cristina Iovita au Théâtre de l’Utopie (Montréal, mars-avril 2010). La première partie examine les rapports entre le personnage de Polonius et celui de Pantalon, personnage typique de la commedia dell’arte qui donne la « clé » de l’adaptation scénique. La deuxième partie présente la reconstruction du texte de Shakespeare sur les structures de base de la commedia dell’arte, structures identifiées et inspirées par la « scène des acteurs » (Acte II, Scène 2) du texte original. La troisième partie suit les innovations de style amenées par l’insertion dans la trame scénique du tango argentin, une danse narrative de type populaire exprimant les rites de la passion. La conclusion porte sur le potentiel d’actualisation du répertoire classique par la récupération des moyens scéniques traditionnels.
L’esthétique théâtrale chez le jeune Albert Camus
Authors: Bastien Sophie 
Published: November 2014

Cet article expose d’abord les nombreuses activités créatrices qu’a exercées Albert Camus en lien avec le théâtre, tant comme art scénique que comme genre littéraire. Sa partie centrale, ensuite, se penche sur la production de la première troupe camusienne, le « Théâtre du Travail », dans les années trente à Alger. En examinant ce pan de la carrière de Camus que la critique a éludé, elle met au jour une esthétique surprenante. L’article montre finalement en quoi ces audaces formelles annoncent des traits fondamentaux du répertoire camusien plus connu (celui de la décennie quarante), et se retrouvent aussi chez l’homme de métier qui prospère au Festival d’Angers dans les années cinquante.
Actions on nutrition education with children in daycare university – representatives’ and teachers’ perception about the playful
Authors: Sá Selma Petra Chaves , Azeredo Elizabeth Azevedo , Lavoyer Cristina Escudeiro 
Published: November 2014

Objetivos: Analisar as ações educativas nutricionais implementadas com pré- escolares em creche universitária na visão dos responsáveis e descrever a percepção dos responsáveis dos pré-escolares sobre as ações educativas aplicadas. Método: Estudo com abordagem qualitativa, descritiva utilizando a técnica de Grupo Focal com os responsáveis e de entrevista semi estruturada com os professores da Creche daUniversidade Federal Fluminense que foram submetidos às ações educativas. Realizou-se análise de conteúdo segundo Bardin além do pensamento de Vygostki relacionado ao processo de ensino aprendizagem. Resultados: A partir da análise emergiram duas categorias: Ações em Educação Alimentar e Nutricional na percepção dos professores; e Ações em Educação Alimentar e Nutricional – as mudanças no hábito alimentar na visão dos professores. Conclusões: pode-se dizer que houve o aprendizado através das atividades lúdicas em um momento de descontração para crianças onde o ato culinário foi uma pratica de integração social.
Endovascular Stroke Thrombectomy for Patients With Large Ischemic Core
Authors: Chen Huanwen , Lee Jin Soo , Michel Patrik , Yan Bernard , Chaturvedi Seemant 
Published: August 2024

ImportanceRecently, 6 randomized clinical trials—RESCUE-Japan-LIMIT (Recovery by Endovascular Salvage for Cerebral Ultra-Acute Embolism—Japan Large Ischemic Core Trial), ANGEL-ASPECT (Trial of Endovascular Therapy for Acute Ischemic Stroke With Large Infarct), SELECT2 (Trial of Endovascular Thrombectomy for Large Ischemic Strokes), TESLA (Thrombectomy for Emergent Salvage of Large Anterior Circulation Ischemic Stroke), TENSION (Endovascular Thrombectomy for Acute Ischemic Stroke With Established Large Infarct), and LASTE (Large Stroke Therapy Evaluation)—have concluded their investigations on the efficacy and safety of endovascular thrombectomy (EVT) for the treatment of patients with ischemic stroke, anterior-circulation large vessel occlusions, and large areas of ischemic changes defined as an Alberta Stroke Program Early Computed Tomography Score (ASPECTS) of 5 or less. Overall, the results appeared to be positive, with 5 of the 6 trials meeting their primary efficacy end point, and 1 trial that was a near miss. However, questions remain regarding how these trial results should be interpreted and incorporated into routine clinical practice.ObservationsIn this narrative review and analysis of published trials, important nuances of the available clinical data were identified, and important areas of lingering uncertainty were highlighted, including the efficacy and safety of EVT for patients with a low ASPECTS score in late treatment windows and those with large core volumes. Also emphasized was the possibly important role of advanced neuroimaging modalities such as perfusion and magnetic resonance imaging when making EVT treatment decisions for select patients with low ASPECTS scores.Conclusions and RelevanceRecent trial data provide strong evidence that EVT is safe and effective for patients with anterior, large vessel–occlusion stroke and low ASPECTS scores who present within 6 hours from stroke onset. However, patient outcomes often remain poor despite EVT treatment. The efficacy and safety of EVT for patients with low ASPECTS scores who present beyond 6 hours of stroke onset remain uncertain, and the current trial data seem too scarce to justify forgoing advanced stroke imaging during this extended time window. Furthermore, the efficacy and safety of EVT for patients with large core volumes (100 mL or greater) or M2 occlusions (ie, occlusions of the second segment of the middle cerebral artery) remain uncertain. Future research to better identify patients likely to meaningfully respond to EVT is needed to further optimize the stroke triage process and health care resource utilization.
Evaluating the Associations Among Dysautonomia, Gastrointestinal Transit, and Clinical Phenotype in Patients With Systemic Sclerosis
Authors: Alvarez‐Hernandez Maria Paula , Adler Brittany , Perin Jamie , Hughes Michael , McMahan Zsuzsanna H. 
Published: August 2024

ObjectiveOur objective was to identify patients with systemic sclerosis (SSc) with a high burden of autonomic symptoms and to determine whether they have a distinct clinical phenotype, gastrointestinal (GI) transit, or extraintestinal features.MethodsIn a prospective cohort of patients with SSc with GI disease, clinical data were systematically obtained at routine visits. Dysautonomia was identified by the Composite Autonomic Symptom Score (COMPASS)‐31questionnaire. GI transit was measured by whole‐gut scintigraphy. Associations between total COMPASS‐31 scores and clinical features, GI symptoms, and transit were evaluated. Comparisons between patients with global autonomic dysfunction (GAD; ≥5 positive COMPASS‐31 subdomains) and those with limited autonomic dysfunction (LAD; <5 positive subdomains) were also studied.ResultsA total of 91 patients with SSc and GI involvement were included (mean age 57 years, 90% female, 74% limited cutaneous disease, 83% significant GI disease [Medsger score ≥2]). The mean COMPASS‐31 score in patients with SSc was higher than controls (38.8 vs 7.2); 33% had GAD, and 67% had LAD. Patients with GAD were more likely to have limited SSc (93% vs 65%; P < 0.01) and have sicca symptoms (100% vs 77%; P = 0.01). Gastric and colonic transit were faster in patients with GAD (P < 0.05). Upper GI involvement (Medsger GI score of 1 or 2) was associated with higher total COMPASS‐31 scores (P = 0.02).ConclusionSymptoms of global dysautonomia are seen in up to one‐third of patients with SSc and GI involvement. Identifying specific clinical characteristics associated with GAD in SSc will help to identify a population that may benefit from therapies that modulate the autonomic nervous system.image
Identification of fractional Hammerstein systems with the conformable fractional derivative
Authors: Zhang Zhaoming , Mi Wen , Zheng Wei Xing 
Published: August 2024

SummaryIn this article, we study parameter estimation problems for fractional commensurate Hammerstein systems utilizing the conformable fractional derivative. Two algorithms are investigated: first, the Poisson moment functions (PMF) method, aiming to transfer the fractional derivative of the measurement signal into PMF using the fractional Laplace transform and convolution; second, a proposed new instrumental variable algorithm, which is based on the conformable fractional derivative. Both algorithms have been analyzed and shown to be consistent. A comprehensive complexity analysis is provided for each algorithm. Furthermore, a kind of special time‐varying systems are discussed under the conformable fractional derivative. Finally, an example is given to illustrate the effectiveness of the proposed algorithms.
Accurate Identification of Cancer Cells in Complex Pre‐Clinical Models Using a Deep‐Learning Neural Network: A Transfection‐Free Approach
Authors: Cortesi Marilisa , Liu Dongli , Powell Elyse , Barlow Ellen , Warton Kristina , Ford Caroline E. 
Published: August 2024

Abstract3D co‐cultures are key tools for in vitro biomedical research as they recapitulate more closely the in vivo environment while allowing a tighter control on the culture's composition and experimental conditions. The limited technologies available for the analysis of these models, however, hamper their widespread application. The separation of the contribution of the different cell types, in particular, is a fundamental challenge. In this work, ORACLE (OvaRiAn Cancer ceLl rEcognition) is presented, a deep neural network trained to distinguish between ovarian cancer and healthy cells based on the shape of their nucleus. The extensive validation that are conducted includes multiple cell lines and patient‐derived cultures to characterize the effect of all the major potential confounding factors. High accuracy and reliability are maintained throughout the analysis (F1score> 0.9 and Area under the ROC curve ‐ROC‐AUC‐ score = 0.99) demonstrating ORACLE's effectiveness with this detection and classification task. ORACLE is freely available (https://github.com/MarilisaCortesi/ORACLE/tree/main) and can be used to recognize both ovarian cancer cell lines and primary patient‐derived cells. This feature is unique to ORACLE and thus enables for the first time the analysis of in vitro co‐cultures comprised solely of patient‐derived cells.
Bimetallic Nanozymes‐Integrated Parachute‐Like Au2Pt@PMO@ICG Janus Nanomotor with Dual Propulsion for Enhanced Tumor Penetration and Synergistic PTT/PDT/CDT Cancer Therapy
Authors: Zhang Xiaolei , Lyu Yangsai , Li Jia , Yang Xiaohan , Lan Ziwei , Chen Zhixu 
Published: August 2024

AbstractNanocatalytic therapeutic agents with triple synergistic treatment modes of chemodynamic therapy (CDT), photothermal therapy (PTT) and photodynamic therapy (PDT) are emerging nanomaterials in malignancy treatment. Nevertheless, the passive diffusion and transport of nanomaterials result in poor permeability in tumor lesions, severely affecting the effectiveness of synergistic therapy. Herein, a dual‐source‐driven parachute‐like Au2Pt@PMO@ICG Janus nanomotor (APIJNS) is prepared by an interfacial energy‐mediated anisotropic growth strategy for PTT‐mediated CDT/PDT triple synergistic cancer therapy. Such nanomotor can realize self‐thermophoresis drive under the trigger of near‐infrared light, which can effectively enhance the active permeability and uptake of the APIJNS in the tumor tissue, thus achieving efficient PTT/PDT/CDT synergistic therapeutic effect. In addition, parachute‐like APIJNS exhibits high‐efficiency catalase (CAT)‐like activity and can catalyze the overexpressed H2O2 in the tumor microenvironment (TME) to generate oxygen (O2), not only alleviating the hypoxia in the tumor lesion, but also converting it into singlet oxygen (1O2) to activate the photosensitizer ICG, achieving PDT. This work provides new ideas for enhancing triple synergistic cancer therapy by improving tumor permeability with dual‐drive Janus nanomotors based on dual noble metal nanozymes.
Neutral‐Colored Transparent Radiative Cooler by Tailoring Solar Absorption with Punctured Bragg Reflectors
Authors: Ko Byoungsu , Noh Jaebum , Chae Dongwoo , Lee Chihun , Lim Hangyu , Lee Heon , Rho Junsuk 
Published: August 2024

Abstract
Daytime radiative cooling (DRC) has emerged as a promising method for temperature reduction of surfaces exposed to sunlight, without energy consumption. Despite advancements in DRC design, existing reflector‐based methodologies often lack transparency because of visible reflection, hindering the widespread application of this technology using glass. Efforts to address this challenge have led to the development of transparent radiative cooling (TRC), although efficient cooling during daylight remains challenging because of the dominant solar energy absorption. This paper proposes a novel TRC design comprising a polydimethylsiloxane (PDMS) emitter atop a transparent dual‐reflector structure. An optimized Bragg reflector (OBR) and a 90 µm‐hole‐punctured Ag window screen reflector (WR) are used to reflect band A of the near‐infrared (NIR) spectrum (0.74 < λ < 1.4 µm) and the overall solar spectrum, respectively. During the daytime, the proposed TRC lowers the temperature by 22.1 °C through the transparent dual reflector system, compared to a PDMS‐coated glass. Thus, this approach optimizes the balance between solar reflection and visibility using a dual reflector, offering an optimal solution for applications requiring both cooling and transparency.
Urea Induces Uniform Tin Deposition for Long Cycle‐Life Tin‐based Redox Flow Battery
Authors: Yang Yang , Xiang Yan , Yang Yuewen , Xie Xian , Mushtaq Faheem , Zhang Ruiqin , Daoud Walid A. 
Published: August 2024

AbstractAmong multivalent redox flow batteries, the Zn‐based redox flow battery (RFB) has the advantages of high energy density, nontoxicity, and low cost. However, the severe dendrite issue hinders its deployment. Therefore, the Sn‐based RFB is reported as a prospective alternative, particularly in alkaline systems, due to its lower redox potential and four electrons transfer in redox reactions. However, the continuous growth of Sn during charge forms large Sn bulk, which increases the risk of “dead Sn” formation. By combining experiments and theoretical calculations, urea is proposed as an electrolyte additive to regulate Sn deposition on graphite felt. This is achieved through the enhanced adsorption and robust reaction of Sn(OH)62− with graphite felt. Consequently, a more uniform morphology ensues, reducing “dead Sn” formation and thus improving the average discharge voltage and areal capacity. Moreover, the Columbic efficiency becomes more stable, extending the cycle life to over 420 h (>200 cycles) without deep discharge during cycling. This study demonstrates the role of urea in achieving high‐performance Sn‐I flow battery with long cycle life, paving the way for further development of metal‐based hybrid RFBs.
The Bioactive Interface of Titanium Implant with Both Anti‐Oxidative Stress and Immunomodulatory Properties for Enhancing Osseointegration under Diabetic Condition
Authors: Wu Jianshuang , Chen Maowen , Xiao Yao , Yang Huan , Wang Gaoyang , Zhang Xiaohong , Dai Liangliang , Yuan Zhang 
Published: August 2024

AbstractThe poor implant‐osseointegration under diabetic condition remains a challenge to be addressed urgently. Studies have confirmed that the diabetic pathological microenvironment is accompanied by excessive oxidative stress, imbalanced immune homeostasis, and persistent chronic inflammation, which seriously impairs the osteogenic process. Herein, a multifunctional bioactive interface with both anti‐oxidative stress and immunomodulatory properties is constructed on titanium implants. Briefly, manganese dioxide nanosheets are coated onto mesoporous polydopamine nanoparticles loaded with carbon monoxide gas precursor, namely MnO2‐CO@MPDA NPs, and then they are integrated on the titanium implant to obtain MCM‐Ti. In the simulated diabetic microenvironment, under the action of MnO2 nanoenzymes, MCM‐Ti can effectively eliminate intracellular reactive oxygen species while alleviating hypoxic state. Interestingly, the microenvironment mediates the responsive release of CO gas, which effectively drives macrophages toward M2 polarization, thereby ameliorating inflammatory response. The potential mechanism is that CO gas up‐regulates the expression of heme oxygenase‐1, further activating the Notch/Hes1/Stat3 signaling pathway. Furthermore, the conditioned medium derived from macrophages on MCM‐Ti surface significantly enhances the osteogenic differentiation of BMSCs. In a type 2 diabetic rat model, MCM‐Ti implant effectively alleviates the accompanying inflammation and enhances the osseointegration through the synergistic effects of resisting oxidative stress and remodeling immune homeostasis.
Development of a Novel Solid State Organic Fluorophore: Excited‐State Aromatization‐Induced Structural Planarization
Authors: Pace Domenic P. , Crocker Reece D. , Kendrick William J. , Zhang Bolong , Wong Wallace W. H. , Mai Binh Khanh , Schmidt Timothy W. , Nguyen Thanh Vinh 
Published: August 2024

AbstractSolid‐state emission is pivotal for the functionality of organic compounds in opto‐electronic applications. Yet, tailoring the emission characteristics of existing solid‐state emissive organic frameworks is a challenging task, primarily due to their intricate structure‐activity interplay. In this study, an innovative family of solid‐state luminogens, centered around the dibenzosuberenylidene core are introduced. These luminogens are characterized by a remarkable excited‐state aromatization‐induced structural planarization (ESAISP) behavior. This unique feature allows for the modulation of their fluorescence properties, including color and intensity, through simple structural alterations, opening new avenues in the development of organic advanced functional materials.