bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nasal intermittent positive pressure ventilation versus nasal continuous positive airway pressure for preterm infants with respiratory distress syndrome: A meta‐analysis and up‐date
Authors: Li Wang , Long Chen , Zhangxue Hu , Jinning Zhao , Shifang Tang , Juan Ma , Renjun Li , Yuan Shi 
Published: November 2014

SummaryObjectiveTo evaluate whether nasal intermittent positive pressure ventilation (NIPPV) would decrease the requirement for endotracheal ventilation compared with nasal continuous positive airway pressure(NCPAP) for preterm infants with respiratory distress syndrome (RDS) and compare the related complications between these two noninvasive variations of respiratory supportMethodsA search of major electronic databases, including Medline (1980–2013) and the Cochrane Central Register of Controlled Trials, for randomized controlled trials that compared NIPPV versus NCPAP for preterm infants with RDS was performed.Main ResultsSix randomized controlled trials met selection criteria (n = 1,527). The meta‐analyses demonstrated significant decrease in the need for invasive ventilation in the NIPPV group (RR:0.53; 95% CI, 0.33–0.85). In the subgroup of infants who received surfactant also demonstrated a significant rate of failure of nasal support in the NIPPV group (RR:0.57; 95% CI 0.42–0.78). However, the subgroup of infants whose gestational age (GA) ≤ 30 weeks or birth weight (BW) < 1,500 g showed no difference between the two groups (RR:0.59; 95% CI 0.27–1.26); and the subgroup of infants whose GA > 30 weeks or BW > 1,500 g also showed no difference between the two groups (RR:0.63; 95% CI 0.29–1.39). No differences in other outcome variables were observed between the two groups.ConclusionsAmong preterm infants with RDS, there was a significant decrease in the need for invasive ventilation in the NIPPV group as compared with NCPAP group, especially for the infants who received surfactant. However, NIPPV could not decrease the need for invasive ventilation both in the subgroup of infants whose GA ≤ 30 weeks or BW < 1,500 g and the subgroup of infants with BW of >30 weeks or BW > 1,500 g. It is limited to analysis the primary outcome generally. Larger trials of this intervention are needed to assess the difference in this primary outcome and the related complications between both forms of noninvasive respiratory support. Pediatr Pulmonol. 2015; 50:402–409. © 2014 Wiley Periodicals, Inc.
Materials Research for Group IV Semiconductors
Authors: Pizzini Sergio and , Kissinger Gudrun 
Published: November 2014

AbstractThis volume is a collection of papers presented at Symposium X “Materials Research for Group IV Semiconductors: Growth, Characterization, and Technological Developments” at the E‐MRS Spring Meeting 2014 held from May 26–30 in Lille, France.Different from the recent past, the major challenges for fundamental research and technological development in microelectronics and photovoltaics are no more confined to bulk silicon and silicon devices but to a variety of options based on silicon alloys, nanocrystalline silicon, silicon nanowires, Ge films on silicon, and graphene. Group IV elements are dominating microelectronics, photovoltaics, and nano‐technology in their whole variety and with ongoing innovation potential.The overall development is driven more and more by defect engineering procedures, optimized deposition processes and growth techniques, advanced diagnostics and modeling tools. Basic research on point defects and extended defects remains in the center of interest for both electronic and photovoltaic applications, being still important for solving defect related problems, for improved defect engineering, and to increase the efficiency of gettering processes in photovoltaic and electronic materials.Crystal growth for electronic applications moves towards 450 mm diameter silicon ingots while photovoltaic applications are seeking a tradeoff between high quality of large volumes and cost efficiency. Advanced float‐zone processes open new opportunities, and modeling of crystal growth and defect generation for Si, Ge and Si–Ge alloys can help to facilitate these developments.Optimization of epitaxial deposition of nitrides on silicon substrates as well as novel methods for the growth of graphene on silicon are in the center of interest because of their innovation potential for the optoelectronic and microelectronic industry. Selective epitaxy for advanced electronic applications and strain engineering in strained layer epitaxy are still important for the heterogeneous integration of Si or Ge in high‐end silicon device technologies.Eventually, nanocrystalline group IV semiconductors in their whole variety from quantum dots, nanowires and superlattices offer a number of novel opportunities for new applications in view of “more than Moore”.The symposium addressed its interest to all these topics and provided a successful forum for scientists coming from research institutions and industry of Asia, America, Australia, Africa, and Europe to discuss recent results and developments in materials research on group IV elements. In total, 72 oral and 113 poster presentations have made this symposium a fruitful expert meeting, with mutual benefits arising from technical and scientific interactions between academy and industry. (© 2014 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Adults with Chromosome 18 Abnormalities
Authors: Soileau Bridgette , Hasi Minire , Sebold Courtney , Hill Annice , O'Donnell Louise , Hale Daniel E. , Cody Jannine D. 
Published: November 2014

AbstractThe identification of an underlying chromosome abnormality frequently marks the endpoint of a diagnostic odyssey. However, families are frequently left with more questions than answers as they consider their child's future. In the case of rare chromosome conditions, a lack of longitudinal data often makes it difficult to provide anticipatory guidance to these families. The objective of this study is to describe the lifespan, educational attainment, living situation, and behavioral phenotype of adults with chromosome 18 abnormalities. The Chromosome 18 Clinical Research Center has enrolled 483 individuals with one of the following conditions: 18q‐, 18p‐, Tetrasomy 18p, and Ring 18. As a part of the ongoing longitudinal study, we collect data on living arrangements, educational level attained, and employment status as well as data on executive functioning and behavioral skills on an annual basis. Within our cohort, 28 of the 483 participants have died, the majority of whom have deletions encompassing the TCF4 gene or who have unbalanced rearrangement involving other chromosomes. Data regarding the cause of and age at death are presented. We also report on the living situation, educational attainment, and behavioral phenotype of the 151 participants over the age of 18. In general, educational level is higher for people with all these conditions than implied by the early literature, including some that received post‐high school education. In addition, some individuals are able to live independently, though at this point they represent a minority of patients. Data on executive function and behavioral phenotype are also presented. Taken together, these data provide insight into the long‐term outcome for individuals with a chromosome 18 condition. This information is critical in counseling families on the range of potential outcomes for their child.
Antigen‐extracted xenogeneic cancellous bone graft with recombinant human bone morphogenetic protein‐2 enhances bone regeneration in repair of mandibular defect in rabbits
Authors: Li Ze‐jian , Lu Chun‐ting , Feng Zhi‐qiang , Zhao Qing‐tong , Zhou Zhi‐ying , Lai Ren‐fa 
Published: November 2014

AbstractThe effects of a large‐piece of xenogeneic bone that was separated from healthy pigs as a scaffold for the repair of a mandibular defect was investigated, and the applicability of antigen‐extracted xenogeneic cancellous bone (AXCB) soaked with recombinant human bone morphogenetic protein‐2 (rhBMP‐2) in bone defect repair was assessed. Mandibular defects were created in 48 New Zealand rabbits, and the animals were randomly divided into four groups, in which the mandibular defects were grafted with AXCB, AXCB soaked with rhBMP‐2, and autograft bone, or left blank. An equal number of animals from each group were classified into three time points (4, 8, and 12 weeks) after surgery for gross pathological observation, hematoxylin and eosin (H and E) staining, radiographic examination, and bone density measurement. H and E staining revealed that the area percentage of bone regeneration in the group of the AXCB/rhBMP‐2 graft was 27.72 ± 4.68, 53.90 ± 21.92, and 77.35 ± 9.83 at 4 weeks, 8 weeks, and 12 weeks, respectively. These results were better than those of the autogenous bone graft, suggesting that the group of the AXCB/rhBMP‐2 graft achieved a good osteogenic effect. With regard to the AXCB graft without rhBMP‐2, the area percentage of bone regeneration was only 14.03 ± 5.02, 28.49 ± 11.35, and 53.90 ± 21.92. Therefore, the osteogenic effect of the AXCB/rhBMP‐2 graft was demonstrated to have the best effect. In the group of the AXCB/rhBMP‐2 graft, the area percentage of bone regeneration increased, and the implanted materials were gradually degraded and replaced by autogenous bone regeneration over time. We conclude that the AXCB graft soaked with rhBMP‐2 showed good osteogenic effect in the repair of bone defects and good biocompatibility. AXCB serves as a good carrier of rhBMP‐2, which promotes bone formation.
Licensed or Licentious? Examining Regulatory Discussions of Stripping in Ontario
Authors: Law Tuulia 
Published: November 2014

AbstractThis paper reflects on the moralization of the sex industry and the implications thereof in a case study of erotic dance in Ontario since the year 2000. It examines how subjects, objects, and practices are discursively formed and moralized in regulatory discussions of stripping and how subjects engage in and resist moralization. This article argues that in spite of the development of a labour discourse, a discourse moralizing stripping as prostitution, which is, in turn, framed as harmful and deviant, continues to inform regulation.
Family Interactions Regarding Fathers’ Smoking and Cessation in Shanghai, China
Authors: Berg Carla J. , Zheng Pinpin , Kegler Michelle C. 
Published: November 2014

Introduction: Spousal support predicts smoking cessation. China is the world's largest consumer of tobacco, with drastic differences in smoking prevalence among men and women. Thus, understanding marital interactions around husbands’ smoking has implications for cultures with similarly large gender disparities in smoking.Aims: We examined interactions among family members regarding husbands’ smoking in homes with small children in Shanghai.Methods: In Spring 2013, we conducted in-person semi-structured interviews among 13 male smokers and 17 female nonsmokers recruited from an urban and a suburban community in Shanghai.Results/Findings: To encourage husbands’ cessation or reduction, some women reported intervening either directly or indirectly through their children, emphasizing the health consequences for the smoker and the family. Some women reported not conversing about cessation due to concern about conflict, tolerance, or resignation. Women reported that their husbands’ responses to anti-smoking messages from family members included promises to quit in the future or noting the strength of the nicotine addiction and the disadvantages of quitting. Men reported the importance of smoking in work/culture and argued against the research about the harms of smoking.Conclusions: Interventions targeting motivators for cessation among men and to support women in encouraging their husbands’ cessation should be developed.
The Action-Sentence Compatibility Effect in ASL: the role of semantics vs. perception
Authors: SECORA KRISTEN , EMMOREY KAREN 
Published: November 2014

abstractEmbodied theories of cognition propose that humans use sensorimotor systems in processing language. The Action-Sentence Compatibility Effect (ACE) refers to the finding that motor responses are facilitated after comprehending sentences that imply movement in the same direction. In sign languages there is a potential conflict between sensorimotor systems and linguistic semantics: movement away from the signer is perceived as motion toward the comprehender. We examined whether perceptual processing of sign movement or verb semantics modulate the ACE. Deaf ASL signers performed a semantic judgment task while viewing signed sentences expressing toward or away motion. We found a significant congruency effect relative to the verb’s semantics rather than to the perceived motion. This result indicates that (a) the motor system is involved in the comprehension of a visual–manual language, and (b) motor simulations for sign language are modulated by verb semantics rather than by the perceived visual motion of the hands.
Effects of depression co-morbidity and treatment on quality of life in patients with acute coronary syndrome: the Korean depression in ACS (K-DEPACS) and the escitalopram for depression in ACS (EsDEPACS) study
Authors: Kim J.-M. , Stewart R. , Bae K.-Y. , Kang H.-J. , Kim S.-W. , Shin I.-S. , Hong Y. J. , Ahn Y. , Jeong M. H. , Yoon J.-S. 
Published: November 2014

BackgroundDepression is common after acute coronary syndrome (ACS) with adverse effects on prognosis. There is little evidence on whether depression treatment improves quality of life (QoL) in ACS patients. The aim of this study was to investigate the effects of co-morbid depression and its treatment on QoL in ACS.MethodIn total, 1152 patients were recruited at baseline, 2–14 weeks after a confirmed ACS episode, and 828 were followed 1 year thereafter. Of 446 baseline participants with co-morbid depressive disorders, 300 were randomized to a 24-week double blind trial of escitalopram or placebo, while the remaining 146 received medical treatment only (MTO). QoL was measured by the World Health Organization Quality of Life –Abbreviated form (WHOQOL-BREF).ResultsAt baseline, QoL was significantly lower in patients with co-morbid depressive disorder than those without. QoL improvement was significantly greater in those receiving escitalopram than those receiving placebo over the 24-week treatment period. In the 1-year follow-up, the better outcomes associated with escitalopram remained evident against both placebo and MTO.ConclusionsDepression was significantly associated with worse QoL even in patients with recently developed ACS. Depression treatment was associated with QoL improvement in ACS patients in the 24-week treatment period, the effects of which extended to 1 year.
Aphorismen und Foto-Montagebilder: Was verbindet sie, was vermögen sie?
Authors: Klosinski Gunther 
Published: November 2014

Aphorismen und Foto-Montagebilder als verdichtete Kompositionen entsprechen Wort- und Bildcollagen, denen das spielerische Element innewohnt. Sie wirken im Grenzbereich der Fantasie und des Phantastischen, vermögen anzurühren und tragen therapeutisches Potential in sich im Sinne rezeptiver Kunsttherapie.
Evolutionary non-linear modelling for selecting vaccines against antigenically variable viruses
Authors: Rahman Tameera , Mahapatra Mana , Laing Emma , Jin Yaochu 
Published: November 2014

Abstract
Motivation: In vitro and in vivo selection of vaccines is time consuming, expensive and the selected vaccines may not be able to provide protection against broad-spectrum viruses because of emerging antigenically novel disease strains. A powerful computational model that incorporates these protein/DNA or RNA level fluctuations can effectively predict antigenically variant strains, and can minimize the amount of resources spent on exclusive serological testing of vaccines and make wide spectrum vaccines possible for many diseases. However, in silico vaccine prediction remains a grand challenge. To address the challenge, we investigate the use of linear and non-linear regression models to predict the antigenic similarity in foot-and-mouth disease virus strains and in influenza strains, where the structure and parameters of the non-linear model are optimized using an evolutionary algorithm (EA). In addition, we examine two different scoring methods for weighting the type of amino acid substitutions in the linear and non-linear models. We also test our models with some unseen data.
Results: We achieved the best prediction results on three datasets of SAT2 (Foot-and-Mouth disease), two datasets of serotype A (Foot-and-Mouth disease) and two datasets of influenza when the scoring method based on biochemical properties of amino acids is employed in combination with a non-linear regression model. Models based on substitutions in the antigenic areas performed better than those that took the entire exposed viral capsid proteins. A majority of the non-linear regression models optimized with the EA performed better than the linear and non-linear models whose parameters are estimated using the least-squares method. In addition, for the best models, optimized non-linear regression models consist of more terms than their linear counterparts, implying a non-linear nature of influences of amino acid substitutions. Our models were also tested on five recently generated FMDV datasets and the best model was able to achieve an 80% agreement rate.
Contact: yaochu.jin@surrey.ac.uk or e.laing@surrey.ac.uk
Bioimaging-based detection of mislocalized proteins in human cancers by semi-supervised learning
Authors: Xu Ying-Ying , Yang Fan , Zhang Yang , Shen Hong-Bin 
Published: November 2014

Abstract
Motivation: There is a long-term interest in the challenging task of finding translocated and mislocated cancer biomarker proteins. Bioimages of subcellular protein distribution are new data sources which have attracted much attention in recent years because of their intuitive and detailed descriptions of protein distribution. However, automated methods in large-scale biomarker screening suffer significantly from the lack of subcellular location annotations for bioimages from cancer tissues. The transfer prediction idea of applying models trained on normal tissue proteins to predict the subcellular locations of cancerous ones is arbitrary because the protein distribution patterns may differ in normal and cancerous states.
Results: We developed a new semi-supervised protocol that can use unlabeled cancer protein data in model construction by an iterative and incremental training strategy. Our approach enables us to selectively use the low-quality images in normal states to expand the training sample space and provides a general way for dealing with the small size of annotated images used together with large unannotated ones. Experiments demonstrate that the new semi-supervised protocol can result in improved accuracy and sensitivity of subcellular location difference detection.
Availability and implementation: The data and code are available at: www.csbio.sjtu.edu.cn/bioinf/SemiBiomarker/.
Contact: hbshen@sjtu.edu.cn
Supplementary information: Supplementary data are available at Bioinformatics online.
The Psychological Effect of Weather on Car Purchases
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Authors: Busse Meghan R. , Pope Devin G. , Pope Jaren C. , Silva-Risso Jorge 
Published: November 2014

Abstract
When buying durable goods, consumers must forecast how much utility they will derive from future consumption, including consumption in different states of the world. This can be complicated for consumers because making intertemporal evaluations may expose them to a variety of psychological biases such as present bias, projection bias, and salience effects. We investigate whether consumers are affected by such intertemporal biases when they purchase automobiles. Using data for more than 40 million vehicle transactions, we explore the impact of weather on purchasing decisions. We find that the choice to purchase a convertible or a four-wheel-drive is highly dependent on the weather at the time of purchase in a way that is inconsistent with classical utility theory. We consider a range of rational explanations for the empirical effects we find, but none can explain fully the effects we estimate. We then discuss and explore projection bias and salience as two primary psychological mechanisms that are consistent with our results.
Disproportionate Rise in Clostridium difficile–Associated Hospitalizations Among US Youth With Inflammatory Bowel Disease, 1997–2011
Authors: Sandberg Kelly C. , Davis Matthew M. , Gebremariam Achamyeleh , Adler Jeremy 
Published: November 2014

ABSTRACTObjectives:Our aim was to characterize the temporal changes in burden that Clostridium difficile infection (CDI) added to the hospital care of children and young adults with inflammatory bowel disease (IBD) in the United States.Methods:Retrospective analysis of annual, nationally representative samples of children and young adults with IBD.Results:There was a 5‐fold increase in IBD hospitalizations with CDI from 1997 to 2011 (P for trend <0.01). During the same period, IBD hospitalizations without CDI increased 2‐fold (P for trend <0.01). Mean length of stay for IBD hospitalizations with CDI was consistently longer than that for hospitalizations without CDI and did not significantly change over time (P for trend = 0.47). CDI‐related total hospital days in the United States rose from 1702 to 10,194 days per million individuals per year from 1997 to 2011 (P for trend <0.01). Children and young adults hospitalized with CDI had a significantly lower odds of colectomy (0.31) compared with those without CDI. Total charges for CDI‐related hospitalizations among children and young adults in the United States rose from $8.7 million in 1997 to $68.2 million in 2011.Conclusions:A widening gap in burden has opened between IBD hospitalizations with and without CDI during the last decade and a half. CDI‐related hospitalizations are associated with disproportionately longer lengths of stay, more hospital days, and more charges than hospitalizations without CDI over time. Further work within health systems, hospitals, and practices can help us better understand this enlarging gap to improve clinical care for this vulnerable population.
Biological determinants of spontaneous late preterm and early term birth: a retrospective cohort study
Authors: Brown HK , Speechley KN , Macnab J , Natale R , Campbell MK 
Published: November 2014

ObjectiveOur aim was to examine the association between biological determinants of preterm birth (infection and inflammation, placental ischaemia and other hypoxia, diabetes mellitus, other) and spontaneous late preterm (34–36 weeks) and early term (37–38 weeks) birth.DesignRetrospective cohort study.SettingCity of London and Middlesex County, Canada.SampleSingleton live births, delivered at 34–41 weeks to London‐Middlesex mothers following spontaneous labour.MethodsData were obtained from a city‐wide perinatal database on births between 2002 and 2011 (n = 17 678). Multivariable analyses used multinomial logistic regression.Main outcome measureThe outcome of interest was the occurrence of late preterm (34–36 weeks) and early term (37–38 weeks) birth, compared with full term birth (39–41 weeks).ResultsAfter controlling for covariates, there were associations between infection and inflammation and late preterm birth (aOR = 2.07, 95% CI 1.65, 2.60); between placental ischaemia and other hypoxia and late preterm (aOR = 2.21, 95% CI 1.88, 2.61) and early term (aOR = 1.25, 95% CI 1.13, 1.39) birth; between diabetes mellitus and late preterm (aOR = 3.89, 95% CI 2.90, 5.21) and early term (aOR = 2.66, 95% CI 2.19, 3.23) birth; and between other biological determinants (polyhydramnios, oligohydramnios) and late preterm (aOR = 2.81, 95% CI 1.70, 4.64) and early term (aOR = 1.89, 95% CI 1.32, 2.70) birth.ConclusionsOur findings show that delivery following spontaneous labour even close to full term may be a result of pathological processes. Because these biological determinants of preterm birth contribute to an adverse intrauterine environment, they have important implications for fetal and neonatal health.