bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of intramuscular alfaxalone and dexmedetomidine alone and combined on ocular, electroretinographic, and cardiorespiratory parameters in normal cats
Authors: Guo Yizhe , Mao Sichao , Zhou Zhenlei 
Published: July 2024

BackgroundThis study aimed to determine the effects of intramuscular (IM) administration of alfaxalone with or without dexmedetomidine on short electroretinography (ERG), ocular parameters and cardiorespiratory in healthy cats.MethodsEight healthy female spayed cats were treated with three sedation protocols: IM administration of 5 μg/kg dexmedetomidine (DEX), 5 mg/kg alfaxalone (ALF), and 5 μg/kg dexmedetomidine plus 5 mg/kg alfaxalone (DEX + ALF). The washout period after each treatment was 2 weeks. Physiological parameters, time metrics, intraocular pressure (IOP), Schirmer tear test 1 (STT-1) and a short ERG protocol were recorded. For age data, weight data, time metrics and ERG data, one-way ANOVA with Bonferroni posterior comparisons were performed. For physiological parameters, IOP and STT-1 data, two-way repeated measures ANOVA with Bonferroni posterior comparisons were performed. Statistical significance was set at a p-value &lt;0.05.ResultsIOPs were increased in all three groups compared to baseline and showed no significant differences among three groups at any time point. STT-1 values were decreased significantly during the process. Significant differences were noticed between a-wave amplitude in the dark-adapted response between DEX and ALF, and a-wave amplitude in light-adapted response between ALF and DEX + ALF.ConclusionThis study demonstrates the feasibility of three sedation protocols for short ERG recording in cats. All these treatments resulted in increased IOP values and reduced STT-1 values. But baseline data of ERG was not obtained as a blank control in cats.
Evaluation of Decay Kinetics of Black Elderberry Antioxidants from Fruits and Flowers
Authors: Golonka Iwona , Dryś Andrzej , Podgórska Katarzyna , Polewska Joanna , Musiał Witold 
Published: July 2024

The health-promoting properties of black elderberry are related to its high content of polyphenols (natural antioxidants), which eliminate free radicals and prevent the formation of oxidative stress responsible for many diseases. The aim of this work was to determine, the anti-radical effect of Sambucus nigra infusions based on the reaction with 2,2-diphenyl-1-picrylhydrazyl (DPPH) and galvinoxyl (Glv) radicals and to determine the function describing the disappearance curves of these radicals. The antioxidant properties of infusions obtained from the flowers and fruits of this plant were tested using the modified Brand-Williams method using DPPH and Glv radicals. Higher antioxidant activity towards both the DPPH and Glv radicals was found in flowers compared to fruits. In addition, it was found that the process of quenching radicals in the reaction with Sambucus nigra infusions proceeds in accordance with the assumptions of second-order reaction kinetics. The infusion obtained from flowers quenched radicals faster than fruit infusions. The applied second-order kinetics equation may enable estimation of antioxidants levels in natural sources of radicals.
Análise sobre a incidência do aumento dos casos de Herpes Zoster associado a pandemia do COVID-19: uma revisão bibliográfica
Authors: Brito Ana Deyse Fontenele , Costa Luana Negreiros , Braga Lívia Mourão , Araújo Fernando Luiz Oliveira de 
Published: July 2024

Introdução: A pandemia causada pelo agente patogénico SARS-CoV-2 tem representado uma grande preocupação para todas as especialidades médicas, devido ao amplo espectro de sinais e sintomas observados. Existem hipóteses de uma relação causa-efeito dos quadros cutâneos provocados pelo vírus da varicela zoster (VZV) com a infecção pelo novo coronavírus em virtude do vínculo temporal entre a eclosão de tais quadros. O VZV é um vírus neurotrópico humano que provoca tanto a varicela quanto o herpes zoster (HZ). Objetivos: Objetiva-se fazer uma meta-análise dos casos e avaliar a correlação entre o COVID-19 e os crescentes números de herpes zoster na população. Metodologia: Para tanto, foram realizadas pesquisas bibliográficas utilizando sites de publicações científicas, sendo incluídos estudos que mencionaram a relação abordada entre os dois vírus, além da vacinação do COVID-19. Resultados: Desse modo, observa-se que houveram diversos casos (n=477) de surgimento de herpes zoster. Os sintomas variam desde ocorrências mais simples até sintomas mais graves. Atualmente, a associação entre a HZ e a COVID-19 é incerta, no entanto uma desregulação do sistema imunológico associada ao estresse emocional e seu comportamento no organismo poderia ser um fator envolvido para um gatilho na reativação viral por Varicela Zoster/Herpes Zoster, além das respostas celulares da vacinação no organismo. Nesse sentido, a discussão proposta torna-se relevante visto que as manifestações cutâneas associadas ao SARS-CoV-2 ainda vem sendo descritas na literatura científica. Conclusão: Esse estudo demonstrou por meio de dados estatísticos a provável conexão entre o aumento de casos de HZ associados ao COVID-19.
Nirsevimabe - anticorpo monoclonal na prevenção contra bronquiolite viral aguda
Authors: Gashti Sarah Menezes , Peixoto Kaline Aragão , Araujo Letícia Nogueira Carvalho Costa de , Muniz Rayssa Alves , Reis Sara Oliveira , Oliveira Thaynara Rodrigues de , Mundim Renato Resende 
Published: July 2024

Objetivo: Revisar a literatura com o objetivo de discutir e comparar uso do anticorpo monoclonal Nirsevimabe e do Palivizumabe. Revisão Bibliográfica: A bronquiolite viral aguda é uma enfermidade responsável por alta prevalência de infecções, hospitalizações e, até mesmo, óbitos pediátricos; e o fato de não haver tratamento medicamentoso específico, pode agravar o curso da doença. A prevenção e o tratamento precoce são fundamentais para proteger a saúde desses bebês. O Nirsevimabe mostra-se como uma prevenção eficaz e promissora nas infecções contra o vírus sincicial respiratório. Métodos: O estudo é uma revisão narrativa da literatura sobre o uso do Nirsevimabe, um anticorpo monoclonal, na prevenção da bronquiolite viral aguda. Foram utilizados como descritores “Antibodies Monoclonal”, “Viral Bronchiolitis” e “Nirsevimab”, nas plataformas VHL/LILACS, PubMed, SciELO, MEDLINE, Google Acadêmico e nas diretrizes da Sociedade Brasileira de Pediatria. A revisão foi baseada em 15 artigos selecionados que abordam diferentes aspectos do uso do Nirsevimabe na prevenção da doença e de complicações. Considerações Finais: Evidencia-se a importância do Nirsevimabe, pois este apresenta-se de maneira mais potente e possui ação terapêutica mais prolongada, atenuando as formas graves da bronquiolite viral aguda.
Acidente Vascular Cerebral decorrente de Angiomatose Encefalotrigeminal em paciente pediátrico: um relato de caso
Authors: Freitas Lucas Diniz Nascimento de , Santos Lethícia Rodrigues dos , Goia Amanda , Mahle Victória Droubi , Grillo Ana Luíza Yaekashi 
Published: July 2024

O acidente vascular cerebral (AVC) na população pediátrica é um evento raro e potencialmente fatal. Estima-se que sua incidência seja de 2 a 13 casos por 100.000 crianças a cada ano, sendo mais comum em meninos e lactentes. A identificação imediata da condição é dificultada pela variedade do quadro clínico e ofuscada por outros diagnósticos. Dentre as principais etiologias isquêmicas, a anemia falciforme e as cardiopatias congênitas lideram, enquanto nas hemorrágicas, o trauma e as vasculopatias. O diagnóstico precoce do agente causador do déficit neurológico agudo e a terapia adequada são essenciais para a minimização da morbimortalidade. Apresenta-se o caso de um paciente masculino, 9 anos, admitido no Pronto Atendimento por vômitos, obnubilação e hemiparesia direita há um dia. Após estabilização clínica e descarte de sangramento craniano pelo exame tomográfico, foi avaliado pela neurocirurgia e diagnosticado com AVC isquêmico. Em seguida o paciente foi internado em uma Unidade de Terapia Intensiva Pediátrica para receber o tratamento e seguir na investigação. Frente à escassez de dados a respeito da isquemia cerebral aguda decorrente de angiomatoses em escolares, este caso ressalta a importância do diagnóstico precoce e manejo adequado das doenças cerebrovasculares na pediatria. Além disso, destaca a necessidade de analisar as particularidades clínicas e estratégias de tratamento do AVC isquêmico na pediatria.
Analysis of methods for automated processing of analytical data on incidents in crisis management systems
Authors: Игошин Д.Д. 
Published: July 2024

В статье проведён ряд исследований по оптимизации и совершенствованию методов обработки аналитических данных в системах антикризисного управления МЧС России, а именно: обозначены актуальные источники аналитических данных для системы антикризисного управления МЧС России; проведён детальный анализ существующих методов и технологий, позволяющих обрабатывать аналитические данные, а также выявлены их преимущества и недостатки; определены проблемные аспекты, снижающие уровень результатов вычислений существующих методов и технологий обработки аналитических данных; определены дальнейшие пути развития и совершенствования существующих методов и технологий обработки аналитических данных. В результате проведённого исследования автором статьи определены следующие перспективные направления развития автоматизированной обработки аналитических данных о происшествиях в системах антикризисного управления: аналитика в режиме реального времени и мультимодальное обучение. Также, по мнению автора, следует обратить особое внимание на повышение отказоустойчивости специализированных мобильных продуктов, путём развития и внедрения технологий облачных вычислений.
The article contains a number of studies on optimization and improvement of analytical data processing methods in emergency response systems, namely: current sources of analytical data for the anti-crisis management system of the rescue department are identified and described; a detailed analysis of existing methods and technologies for the ability to evaluate and structure heterogeneous data is carried out, their positive and negative sides are demonstrated; related factors influencing the level of calculation results of the selected metrics and analytical data processing methodologies; promising directions in the development of existing approaches and analytical data processing technologies are identified. The result of the research conducted by the author of this article were the conclusions about the need to develop such areas as real-time analytics and multimodal training. Also, according to the author, special attention should be paid to improving the fault tolerance of specialized mobile products through the development and implementation of cloud computing technologies.
Application of subject-oriented interactive learning technologies for training of personnel of the Russian Ministry of Emergency Situations
Authors: Шамсутдинов Г.Ю. , Яровой В.Ю. , Куртов С.О. , Трояк А.Ю. , Ширинкин П.В. 
Published: July 2024

В данной работе рассмотрен вопрос внедрения игровых форм обучения с помощью визуально-ориентированных интерактивных повествований, для подготовки обучающихся высших и профессиональных образовательных организаций МЧС России, а также проверки их знаний и навыков в изучении учебно-методического материала. Проведён анализ существующих деловых игр и программных средств для улучшения усвояемости учебного материала у обучающихся. Разработано программное решение, разработанное на основе специального программного обеспечения компьютерных видеоигр «RenPy» и языка программирования «Python». Указан алгоритм содержания программного обеспечения и указана модель взаимодействия программы с обучающимся. В рамках создания отдельной программы сформирован результат проделанной работы обучающегося – ввод данных, за которыми следует система оценивания «Цифровой эквивалент баллов», каждый отдельный обучающийся академии при прохождении программы получает индивидуальный результат для возможности оценки знаний и навыков. При создании избрана функция объяснения неправильно выбранных ответов для изучения информации, связанную с обучением в виде демонстрации нормативно-правовых актов ведомственных организаций и федеральных законов, данный способ поможет обучающимся не только увидеть свои ошибки, но и объяснить правильный ответ с помощью профессионального языка.This paper considers the issue of introducing game forms of training with the help of visually-oriented interactive narratives, for training students of higher and professional educational organizations of the Ministry of Emergency Situations of Russia, as well as testing their knowledge and skills in the study of educational and methodological material. The analysis of existing business games and software tools for improving the learners' mastery of educational material has been carried out. The authors of the work offer their own software solution developed on the basis of special software of computer video games "RenPy" and programming language "Python". The algorithm of the software content is specified and the model of interaction of the program with the learner is indicated. Within the framework of creation of the separate program the result of the done work of the learner is formed - data input, followed by the evaluation system "Digital equivalent of points", each separate learner of the academy at passing of the program receives the individual result for possibility of estimation of knowledge and skills of the learners. At creation the function of explanation of wrongly chosen answers for studying of the information connected with training in the form of demonstration of normative-legal acts of departmental organizations and federal laws is chosen, the given way will help trainees not only to see the mistakes, but also to explain the correct answer with the help of professional language.
Automated monitoring of explosive fire condition of hydrogen energy facilities
Authors: Мехоношина М.О. 
Published: July 2024

В статье предложен метод снижения взрывопожарной опасности на производственных объектах водородной энергетики на основе адаптивной технологии гарантированного предотвращения пожаров. Разработана модульная структура автоматизированной системы поддержки принятия решений по снижению взрывопожарной опасности производственных объектов водородной энергетики. При разработке структурной схемы автоматизированной системы поддержки принятия решений были учтены факторы, влияющие на безопасное хранение водорода, которые способны при отклонении привести к взрывопожарной ситуации. Данная автоматизированная система поддержки принятия решений позволит свести риски возникновения взрывопожароопасных ситуаций к минимуму за счет непрерывного мониторинга производственного объекта водородной энергетики.
The article proposes a method for reducing explosion and fire hazards at hydrogen energy production facilities based on adaptive technology for guaranteed fire prevention. A modular structure of an automated decision support system has been developed to reduce the explosion and fire hazard of hydrogen energy production facilities. When developing a block diagram of an automated decision support system, factors affecting the safe storage of hydrogen, which, if deviated, can lead to an explosion and fire situation, were taken into account. This automated decision support system will help reduce the risks of explosion and fire situations to a minimum through continuous monitoring of the hydrogen energy production facility.
Algorithm for supporting management decisions on choosing the optimal route for patrolling the waters of St. Petersburg
Authors: Колеров Д.А. 
Published: July 2024

Активная популяризация внутреннего туризма, обилие рек и каналов в черте Санкт-Петербурга, удешевление технологий производства маломерных судов приводят к увеличению числа водных прогулок и любителей рыбалки. Как следствие, наблюдается рост количества происшествий на воде. Для повышения уровня безопасности населения в акватории города в 2020 году принята соответствующая концепция. Однако в результате её анализа было выявлено, что расчёт необходимого числа сил и средств поисково-спасательных служб проводился для благоприятных погодных условий. От 228 до 325 дней на водных объектах Санкт-Петербурга наблюдаются различные неблагоприятные погодные явления, затрудняющие процесс проведения поисково-спасательных работ. Поэтому мероприятий, проводимых в рамках реализации концепции недостаточно для полноценного обеспечения безопасности в акватории. Одним из возможных вариантов повышения уровня безопасности является её патрулирование при неблагоприятных погодных явлениях. Для этих целей в статье разработан алгоритм поддержки принятия управленческий решений по выбору оптимального маршрута патрулирования акватории Санкт-Петербурга на основе метода ветвей и границ и Венгерского метода. Полученные результаты позволяют минимизировать затраты на проведение патрулирования и сократить количество необходимых спасательных судов.The active popularization of domestic tourism, the abundance of rivers and canals within St. Petersburg, the reduction in the cost of production technologies for small boats lead to an increase in the number of boat trips and fishing enthusiasts. As a result, there is an increase in the number of accidents on the water. To increase the level of population safety in the city’s water area, a corresponding concept was adopted in 2020. However, as a result of its analysis, it was revealed that the calculation of the required number of forces and means of search and rescue services was carried out for favorable weather conditions. From 228 to 325 days, various adverse weather phenomena are observed on the water bodies of St. Petersburg, complicating the process of search and rescue operations. Therefore, the activities carried out as part of the implementation of the concept are not enough to fully ensure safety in the water area. One of the possible options for increasing the level of safety is patrolling the water area during adverse weather events. For these purposes, the article has developed an algorithm to support management decision-making for choosing the optimal route for patrolling the waters of St. Petersburg based on the branch and bound method and the Hungarian method. The results obtained make it possible to minimize the costs of patrolling and reduce the number of required rescue vessels.
EXPLORING STUDENTS’ SPEAKING ANXIETY IN CLASSROOM
Authors: Mulyana Sherly Saputri , Burki Audrey Bianca , Helmie Jauhar 
Published: July 2024

ABSTRACTThis research discusses studentsâ€™ speaking anxiety in English classroom. The aims are to investigate the factors that cause studentsâ€™ anxiety in speaking English and the strategies that students use to reduce their anxiety in speaking English. The researcher conducted this research in one of senior high schools in Cianjur and this research used a descriptive qualitative method. The participants of this research were 35 students. The data were obtained from open-ended questionnaire and interview. The techniques of analyzing data were data reduction, data display, and drawing conclusion. The results revealed that there are various factors that cause studentsâ€™ anxiety including apprehension of verbal communication, test anxiety and fear of negative evaluation. Furthermore, the researcher found the strategies that students use to reduce their anxiety in speaking: preparation, relaxation, positive thinking, peer seeking, holding things, socially awkward, gesture/body language and self-entertaining. Keywords: anxiety, students' anxiety, speaking English, factor anxiety, strategies to reduce anxiety
THE IMPLEMENTATION OF STORYTELLING A SHORT STORY TO IMPROVE MIDDLE SCHOOL SUNDANESE STUDENTS' SPEAKING SKILL
Authors: Hayati Nuryani Nisa , Iqlimah Siti , Aminah Siti , Hikam A Suny 
Published: July 2024

Speaking is one of the most important skills in learning English. However, a lot of students are good in reading, writing, and also listening but they are weak in speaking. The purpose of this study was to implement storytelling a short story in students learning process to improve students speaking skill. While storytelling is usually associated with telling a long story, even so this study used short stories. This study used a qualitative method and to perform the research, two sessions were held. The first session was to find out students prior speaking skill and the second session was held after the research was conducted to find out the effectiveness of implementing storytelling a short story to improve students speaking skill. The researchers also used observation and interview to find out students challenge in speaking English. This study involved the second grade middle school of SMP IT Nurul Ittihad. The initial findings revealed that studentsâ€™ score in the second session was higher than in the first session. It can be concluded that there are improvements in students speaking skill.
ANALISIS HAMBATAN SAMPING PADA RUAS JALAN PROF. DR. IR. SOEMANTRI BROJONEGORO UNIVERSITAS LAMPUNG
Authors: Rusnoto Tausiyarji 
Published: July 2024

Penelitian ini dilaksanakan pada bulan FebruariÂ 2023 bertempatÂ di Jalan Prof. Dr. Ir. Soemantri Brojonegoro Universitas Lampung yang bertujuan untuk mengetahui kinerja ruas jalan Prof. Dr. Ir. Soemantri Brojonegoro yang ditinjau dari pengaruh hambatan samping, mencakup volume lalu lintas, kecepatan kendaraan, analisis kerapatan, analisis kapasitas jalan, dan analisis derajat kejenuhan. Analisis yang dilakukan yaitu menggunakan metode kuantitatif dimana data berupa hasil dari observasi atau pengamatan. Hasil penelitian ini adalah volume lalu lintas tertinggi yang terjadi pada hari Senin yaitu sebesar 400 smp/jam dalam periode waktu 16.45-17.00 WIB dengan jumlah volume sebesar 1406 smp/jam, dan volume lalu lintas yang terendah terjadi pada hari Minggu sebesar 91 smp/jam dalam periode waktu 07.00-08.00 WIB dengan jumlah volume sebesar 408 smp/jam. Kecepatan kendaraan terendah terjadi pada hari Senin yaitu sebesar 7 km/jam pada pukul 16.00-17.00 WIB, sedangkan kecepatan tertinggi terjadi pada hari Senin yaitu sebesar 22,72 km/jam pada pukul 07.00-08.00 WIB. Hambatan samping tertinggi terjadi pada hari Senin sebesar 113 pada jam puncak sore pukul 16.00-17.00 WIB dengan kategori kelas hambatan samping rendah. Kerapatan kendaraan adalah sebesar 77 kendaraan/jam dan terjadi pada Senin pukul 16.00-17.00 WIB. Kapasitas jalan pada kondisi kelas hambatan samping tinggi hanya sebesar 1648 smp/jam. Tingkat pelayanan pada jalan Soemantri Brojonegoro Universitas Lampung yang diakibatkan adanya hambatan samping, maka jalan Soemantri Brojonegoro dikategorikan tingkat pelayanan B. Kata kunci: Analisis kerapatan, Analisis kapasitas jalan, Analisis derajat kejenuhan
Detection of Salmonella sp. and Escherichia coli Contamination on Processed Fish Meat
Authors: Putri Monica Karunia , Oktari Agung , Oktiansyah Rian , Ulandari Tiara 
Published: July 2024

Fish is a processed food ingredient with very high water content, causing fish to become perishable due to the growth of bacteria in fish. One of the foods made from processed fish is pempek. Therefore, carrying out excellent handling and processing of these processed food ingredients is necessary. This study aims to detect the presence of Salmonella sp bacteria with SSA (Salmonella Shigella Agar) media and E-coli with EMBA (Eosin Methylene Blue Agar) media in processed food derived from ground fish, namely pempek. Three samples were taken from several Palembang city snacks. The method used is a prediction test by streaking samples on selective media SSA and EMBA scratching. The results showed that all food samples tested to detect the presence of Salmonella sp. using SSA media showed positive results. The detection test results for the contamination of E-coli using EMBA media on the food samples also showed that three samples of pempek made from flour and processed ground fish meat positively contained E-coli bacteria.