bluuebunny/crossref_metadata_2025_split huggingface dataset:
Creating a collaborative learning community in the CIS Sandbox
Authors: Frydenberg Mark 
Published: April 2013

PurposeThe purpose of this paper is to investigate the impact of transforming a traditional university computer lab to create a collaborative learning community known as the CIS Sandbox, by remodeling a physical space and supporting it with a virtual presence through the use of social media tools. The discussion applies Selander's “designs for learning” to frame learning experiences in the CIS Sandbox.Design/methodology/approachTo determine attitudes toward learning in such an environment, students who staffed and visited the physical space during its first semester completed a voluntary survey. The study investigated attitudes of visitors toward both classroom and extracurricular technology learning; participants also shared their views on the effect of creating a collaborative physical learning environment, and the extent to which they also made use of its online presence.FindingsProviding both classroom assistance as well as a space for exploring technology, coupled with a focus on blogs and social media, creates interest in IT among students and contributes to student learning. It also creates an opportunity to foster entrepreneurship among student workers who manage these tools as part of the day‐to‐day operation of the facility.Research limitations/implicationsThe study presents one implementation of a collaborative learning community formed in a renovated computer lab after a preliminary start‐up period and considers signs for learning based on its activities.Practical implicationsThis study presents an innovative model for administering a computer lab, focused on new technologies and peer learning. This approach fosters a sense of entrepreneurship among student workers.Originality/valueWhile many have studied learning space design and features for promoting collaborative learning, this study also describes a virtual presence that extends the lab's services by providing online resources.
The influence of professional identity on the process of nurses' training: an empirical study
Authors: Franco Mário , Tavares Paulo 
Published: April 2013

PurposeThis paper aims to analyze the relationship between professional identity and the training of nurses in the context of change. Specifically, this study aims to focus on two research questions: first, how do nurses experience their professional identity? Second, will professional training have an effect on nurses' developing identity?Design/methodology/approachData were obtained from 173 nurses in a Portuguese hospital. Respondents had to evaluate the degree of importance they gave to several variables about professional identity and training. For data analysis and reliability, the variables were classified using factor analysis. Subsequently, the retained factors and variables underwent multiple regression analysis.FindingsResults indicate that nurses consider they have their own identity, which differentiates them from other health professionals, although they feel their work still lacks socio‐professional recognition, which hinders their autonomous intervention within the multi‐disciplinary team.Research limitations/implicationsThe sample for the study was self‐selected from one hospital, which may limit the generalization of some of the findings and points to the need to resort to larger samples. This study allowed the formation of some measures that can contribute to the value and benefits of nurses' professional training in the Portuguese health system.Originality/valueResearch on professional identity has been relatively scarce. Taking into account the relevance of the research topic for the nursing profession, the study's findings show that identity is of some consequence in nurses' professional training.
Registered nurses' views on nursing competence at residential facilities
Authors: Furåker Carina , Agneta Nilsson 
Published: April 2013

PurposeThe aim of this paper is to describe registered nurses' (RNs') ways of working and their views on what competence they require, make use of and wish to develop when caring for older people at residential facilities.Design/methodology/approachThe participants comprised 23 RNs, trained after 1993 and working at seven residential facilities. The data collection consists of group interviews during spring 2009. The group interviews were subjected to content analysis.FindingsThree main categories and six sub‐categories were identified. The findings show that the majority of RNs work in a consultative way although they are responsible for basic care as well as advanced nursing care. They must rely on the staff's competence. They compare the residential facilities to a “mini‐hospital” and they are often frustrated by the staff's incompetence. Attitudes to research findings and to the use of evidence‐based knowledge were limited.Research limitations/implicationsRNs require extensive theoretical, technical and medical knowledge as well as knowledge related to persons with dementia conditions and psychiatric disorders and how to lead, teach and supervise.Practical implicationsSocial and professional isolation influences competence development and working situation and the differences in leadership influence the quality of nursing care. RNs do not critically reflect on what knowledge they require and make use of and how to search for scientific knowledge and this will have a negative influence on the attitude to the competence.Originality/valueThere is a need of extensive and varied knowledge in evidence‐based nursing as well as in leadership and teaching to be able to work independently.
Remembering “Aunt Emma”: small retailing between nostalgia and a conflicted past
Authors: Logemann Jan 
Published: April 2013

PurposeThis paper calls for a reconsideration of standard narratives regarding the role of small, independent retailers for twentieth‐century urban communities. The paper aims to discuss the issues.Design/methodology/approachTaking the German city of Bremen as an example, the paper problematizes the nostalgic treatment of independent “Aunt Emma” (or “mom‐and‐pop”) stores in Germany during the last quarter of the century, by recounting the often conflict‐laden history of small retailers within the urban community. It draws on primary documents from retail associations, the chamber of commerce, municipal administrations, as well as media coverage.FindingsThe romanticization of the corner grocer overlooked the often divisive role of small store‐keepers in the interwar years as well as the social considerations behind some forms of retail modernization.Originality/valueBeyond the particular examples of Bremen or even Germany, the paper urges historians of modern retailing to critically analyze the everyday role shops and shopkeepers have played within their communities without at the same time embracing a market‐liberal narrative of retail modernization as a function of consumer demand.
The birth of consumer behavior: motivation research in the 1940s and 1950s
Authors: Fullerton Ronald A. 
Published: April 2013

PurposeThe purpose of this paper is to show how 1940s and 1950s motivation research laid the foundations of present day consumer behavior as a discipline.Design/methodology/approachThis research uses standard historical methodology – heavy reliance upon primary sources, avoidance of anachronism, heavy use of contemporary quotations, and effort to explain and interpret.FindingsUsing sociology, anthropology, and clinical psychology to explain how and why consumers buy, motivation research provided business with valuable information, and, in the long run, began today's consumer behavior field of study.Originality/valueThis paper offers a different view of motivation research, stressing its use of sociology and anthropology. It offers a corrective to the prevailing over‐emphasis on Ernest Dichter.
Factors influencing the formation of Chinese and American entrepreneurs
Authors: Lewis Prestin , Wei Lu , Hao Yin , Yong Li , Vaccaro Louis C. 
Published: April 2013

PurposeThere is a dearth of literature aimed at understanding the Chinese entrepreneur. There are even fewer studies that compare Chinese and American entrepreneurs. As the interdependence of the economic superpowers continues to grow, it becomes increasingly important to understand similarities and differences between the two groups. Furthermore, researching the two groups can result in greater understanding of the entrepreneur. The purpose of this paper is to look at how economics, culture and policy influence the formation of established successful entrepreneurs.Design/methodology/approachIn this study Chinese and American researchers collected responses from 279 Chinese and American established entrepreneurs in China and the USA. The goal of the research is to develop greater understanding of how culture, economics and policy influence the formation of their ventures.FindingsThe study's results indicate a significant difference in Chinese and American response to policy. The significant difference in policy response might justify further research, and could indicate that policy is more important to the Chinese entrepreneur.Originality/valueA contribution to existing entrepreneurial theory was made regarding the similarities of networking regardless of cultural environment. A three‐dimensional conceptual model was used, measuring culture, economics and policy.
Gender and ethnicity in business consulting assistance: public policy implications
Authors: Sciglimpaglia Don , Welsh Dianne H.B. , Harris Michael L. 
Published: April 2013

PurposeThe purpose of this paper is to investigate the types of business consulting services most needed by small business owners and entrepreneurs and to examine the role that gender and ethnicity plays in the demand for specialized assistance.Design/methodology/approachA survey was administered to small business owners and entrepreneurs to rate their interest in specialized consulting services. The consulting assistance was divided into strategic, operating and administrative categories based on the framework of Chrisman and Leslie.FindingsOverall, the type of consulting with the highest interest was in the area of operations assistance, followed by strategic assistance and administrative assistance. Although few differences were found between male and female respondents, there were significant differences in the needs of minority women.Research limitations/implicationsThis study demonstrates the need for further research on minority female small business owners and entrepreneurs. In particular, it suggests further investigation of services that could be made available to them.Social implicationsThe results indicate that programs designed to assist minority women might have the greatest potential impact. Specialized attention may be necessary to assist this demographic segment, particularly since prior research indicates that minorities often start with greater resource limitations. Public policies should continue to encourage progress by helping establish a new generation of minority entrepreneurs.Originality/valueThe findings from this study provided current evidence of the specialized needs of minority entrepreneurs. It is important to distinguish the needs of entrepreneurs in today's marketplace, in order to develop the most effective and impactful small business assistance programs.
Inversion of microseismic data for triclinic velocity models
Authors: Grechka Vladimir , Yaskevich Sergey 
Published: April 2013

ABSTRACTModern downhole microseismic surveys often employ geometries in which ray trajectories generated by a collection of locatable events provide full polar and azimuthal coverage, making it possible to estimate the in situ seismic anisotropy. We show that traveltimes and particle motions of the direct P‐ and shear‐waves acquired in such geometries can constrain stiffness tensors of triclinic media. While obtaining all 21 stiffness coefficients of a homogeneous triclinic space simultaneously with locating pertinent microseismic events from data recorded in a single vertical well is relatively straightforward, the same methodology does not necessarily succeed in layered formations because the combination of their vertical heterogeneity and azimuthal anisotropy might invalidate the commonly adopted approximation of the event azimuths by those of the P‐wave polarization vectors. When the event azimuths cannot be derived from the particle motions, traveltimes observed in two or more wells are required to locate the events and build layered triclinic or higher‐symmetry azimuthally anisotropic velocity models. As our numerical tests indicate, the multi‐well event‐location methods are expected to perform better than their single‐well counterparts because they rely solely on triangulation and eliminate the usually pronounced azimuthal uncertainties in the event locations that stem from noises adversely affecting hodogram analysis.
Debate on Neoliberalism in and after the Neoliberal Crisis
Authors: Aalbers Manuel B. 
Published: April 2013

AbstractSocial scientists have started to discuss the causes and consequences of the financial and economic crisis of 2007–09, and have also started debating the role of neoliberalism in and after the crisis. More generally, the crisis is often seen as a crisis of neoliberalism — and indeed it is. Neil Smith has observed that neoliberalism ‘has run out of ideas politically’ but remains dominant. The essays that make up this debate discuss what happened to neoliberalism during and after the global financial — or neoliberal — crisis, and how the heralded death and recovery of neoliberalism affects cities around the globe.
Neoliberalism is Dead … Long Live Neoliberalism!
Authors: Aalbers Manuel B. 
Published: April 2013

AbstractIn this essay I argue that the ideology of neoliberalism may have failed, but that neoliberal practice is alive and kicking. Most of the ‘solutions’ to the crisis are in the spirit of neoliberalism, rather than enraptured by neoliberal spirit. Yet, this neoliberal solution is not a solution; it is part of the problem in the sense that it is leading to more problems — not just today but also in decades to come. This so‐called solution is often presented as Keynesian, but it is only partly so. A better way to classify this solution is as an attempt to save the existing, neoliberal, system. The big crisis of our time did not become a crisis of the hegemony of neoliberalism, because actually existing neoliberalism is flexible enough to influence policy in other ways than through the mantra of free markets: it thrives on presenting existing socioeconomic conditions as failing and neoliberalism as the best solution. Considering the many blows neoliberal ideology has received during this crisis, it should already be dead, but like a creeping cancer neoliberal practice is able to resurface and show up in both new and unexpected, and old and predictable, ways.
Aggregation and mating success of Capnodis tenebrionis (Coleoptera: Buprestidae)
Authors: Bonsignore Carmelo Peter , Jones Therésa Melanie 
Published: April 2013

AbstractAn understanding of the relative importance of extrinsic and intrinsic factors in determining the potential distribution and mating success of individuals is critical for the successful monitoring and management of pest species. Using a combination of field observations and a caged field experiment, we explored the roles of environmental and individual variation on the formation of mating aggregations and mating success in the buprestid beetle Capnodis tenebrionis (Linnaeus, 1767), a pest species of stone fruit trees. Our field observations revealed that the formation of aggregations is influenced by a range of environmental factors including temperature, photoperiod, and population density. However, aggregations were not at random and were more likely to occur on the section of the plant with highest incidence of solar radiation and thus higher temperatures. Data from our experiment with caged beetles in the field further indicate that the reproductive behavior of this species varies with temperature. The probability of a successful mating occurring was also positively related to both male and female size. Females of C. tenebrionis mate several times over a 4‐h period, but generally not with the same male. Information obtained from these studies is useful to define the most appropriate time for pest control, especially adopting strategies that interfere with reproduction.
Gamete donors' satisfaction; gender differences and similarities among oocyte and sperm donors in a national sample
Authors: Skoog Svanberg Agneta , Lampic Claudia , Gejerwall Ann‐Louise , Gudmundsson Johannes , Karlström Per‐olof , Solensten Nils‐Gunnar , Sydsjö Gunilla 
Published: April 2013

AbstractObjectiveTo explore oocyte and sperm donors' emotional stress, experiences of care and satisfaction after donation.DesignProspective multicenter study.SettingsAll fertility clinics performing gamete donation in Sweden during the period 2005 to 2008.PopulationOf 220 eligible oocyte donors who were approached, 181 agreed to complete the first questionnaire and 165 completed the second questionnaire 2 months after oocyte donation. Of 156 eligible sperm donors 119 accepted to complete the first questionnaire before donation. Eighty‐nine participants completed the second questionnaire 2 months after sperm donation.MethodsStandardized and study‐specific questionnaires.Main outcome measuresSatisfaction with the donation, respondents' mental health and overall care.ResultsA larger percentage of sperm donors (97.8%) were satisfied with their overall experience of being a donor than oocyte donors (85.9%, p = 0.003). Some oocyte and sperm donors did not receive sufficient information about practical issues (9.1% and 13.5%, respectively) and future consequences (12.8% and 3.4%, respectively, p = 0.014). The donors' symptoms of anxiety and depression did not show any differences in relation to negative or positive perceptions of satisfaction. The donors who did not indicate ambivalence before treatment were on average almost five times more satisfied compared with those who did indicate ambivalence (odds ratio 4.71; 95% CI 1.34–16.51).ConclusionsMost donors were satisfied with their contribution after the donation. Oocyte and sperm donors who expressed ambivalence before donation were less satisfied after donation. In vitro fertilization staff fulfilled most of the donors' needs for information and care.
Lysophosphatidic acid (LPA) signalling in cell migration and cancer invasion: A focussed review and analysis of LPA receptor gene expression on the basis of more than 1700 cancer microarrays
Authors: Willier Semjon , Butt Elke , Grunewald Thomas G. P. 
Published: April 2013

ABSTRACTLysophosphatidic acid (LPA) is a ubiquitously present signalling molecule involved in diverse cellular processes such as cell migration, proliferation and differentiation. LPA acts as an autocrine and/or paracrine signalling molecule via different G‐protein‐coupled LPA receptors (LPARs) that trigger a broad range of intracellular signalling cascades, especially the RHOA pathway. Mounting evidence suggests a crucial role of the LPA/LPAR‐axis in cancer cell metastasis and promising studies are underway to investigate the therapeutic potential of LPAR‐antagonists. This review summarises current knowledge on how LPA promotes cytoskeletal remodelling to enhance the migratory and invasive properties of cells, which may ultimately contribute to cancer metastasis. Furthermore, we provide comprehensive transcriptome analyses of published microarrays of more than 350 normal tissues and more than 1700 malignant tissues to define the expression signatures of LPARs and the LPA‐generating enzymes autotaxin (ATX) and lipase member 1 (LIPI). These analyses demonstrate that ATX is highly expressed in a variety of carcinomas and sarcomas, whereas LIPI is almost exclusively overexpressed in highly aggressive Ewing's sarcomas, which underscores the potential contribution of LPA in metastatic disease. In addition, these analyses show that different cancer entities display distinct expression signatures of LPARs that distinguish them from one another. Finally, we discuss current approaches to specifically target the LPA/LPAR circuits in experimental cancer therapy.
SFTPC mutations cause SP‐C degradation and aggregate formation without increasing ER stress
Authors: Thurm Tobias , Kaltenborn Eva , Kern Sunčana , Griese Matthias , Zarbock Ralf 
Published: April 2013

AbstractBackgroundMutations in the gene encoding surfactant protein C (SP‐C) cause familial and sporadic interstitial lung disease (ILD), which is associated with considerable morbidity and mortality. Unfortunately, effective therapeutic options are still lacking due to a very limited understanding of pathomechanisms. Knowledge of mutant SP‐C proprotein (proSP‐C) trafficking, processing, intracellular degradation and aggregation is a crucial prerequisite for the development of specific therapies to correct aberrant trafficking and processing of proSP‐C and to hinder accumulation of cytotoxic aggregates.Materials and methodsTo identify possible starting points for therapeutic intervention, we stably transfected A549 alveolar epithelial cells with several proSP‐C mutations previously found in patients suffering from ILD. Effects of mutant proSP‐C were assessed by Western blotting, immunofluorescence and Congo red staining.ResultsA group of mutations (p.I73T, p.L110R, p.A116D and p.L188Q) resulted in aberrant proSP‐C products, which were at least partially trafficked to lamellar bodies. Another group of mutations (p.P30L and p.P115L) was arrested in the endoplasmic reticulum (ER). Except for p.I73T, all mutations led to accumulation of intracellular Congo red–positive aggregates. Enhanced ER stress was detectable in none of these stably transfected cells.ConclusionsDifferent SP‐C mutations have unique consequences for alveolar epithelial cell biology. As these cannot be predicted based upon the localization of the mutation, our data emphasize the importance of studying individual mutations in detail in order to develop mutation‐specific therapies.
Lack of effect of lacosamide on the pharmacokinetic and pharmacodynamic profiles of warfarin
Authors: Stockis Armel , van Lier Jan Jaap , Cawello Willi , Kumke Thomas , Eckhardt Klaus 
Published: April 2013

SummaryPurposeThe aim of this study was to evaluate the effect of the antiepileptic drug lacosamide on the pharmacokinetics and pharmacodynamics of the anticoagulant warfarin.MethodsIn this open‐label, two‐treatment crossover study, 16 healthy adult male volunteers were randomized to receive a single 25‐mg dose of warfarin alone in one period and lacosamide 200 mg twice daily on days 1–9 with a single 25 mg dose of warfarin coadministered on day 3 in the other period. There was a 2‐week washout between treatments. Pharmacokinetic end points were area under the plasma concentration–time curve (AUC(0,last) and AUC(0,∞)) and maximum plasma concentration (Cmax) for S‐ and R‐warfarin. Pharmacodynamic end points were area under the international normalized ratio (INR)–time curve (AUCINR), maximum INR (INRmax), maximum prothrombin time (PTmax) and area under the PT‐time curve (AUCPT).Key FindingsFollowing warfarin and lacosamide coadministration, Cmax and AUC of S‐ and R‐warfarin, as well as peak value and AUC of PT and INR, were equivalent to those after warfarin alone. In particular, the AUC(0,∞) ratio (90% confidence interval) for coadministration of warfarin and lacosamide versus warfarin alone was 0.97 (0.94–1.00) for S‐warfarin and 1.05 (1.02–1.09) for R‐warfarin, and the AUCINR ratio was 1.04 (1.01–1.06). All participants completed the study.SignificanceCoadministration of lacosamide 400 mg/day did not alter the pharmacokinetics of warfarin 25 mg or the anticoagulation level. These results suggest that there is no need for dose adjustment of warfarin when coadministered with lacosamide.