bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analisis Persepsi Masyarakat Indonesia Terhadap Hiperlipidemia “Studi pada Sosial Media Twitter”
Authors: Hasan Murojil , Weidyaningsih Chairun , Yasin Nanang Munif 
Published: July 2024

Hiperlipidemia merupakan salah satu Penyakit tidak menular yang disebabkan oleh berbagai macam faktor seperti sosioekonomi, budaya, adat, kebiasaan dan gaya hidup seseorang. Dengan adanya interaksi antar pengguna pada media sosial yang didalamnya berisi informasi, keluhan, saran maupun permintaan bantuan dapat menjadi alat untuk dapat mengetahui persepsi publik yang berguna sebagai bahan intervensi guna menekan laju terjadinya hiperlipidemia di Indonesia. Penelitian ini bertujuan untuk mengetahui faktor yang berpengaruh terhadap persepsi masyarakat terhadap hiperlipidemia yang dihasilkan pada platform media sosial twitter. Data tweet diambil dari unggahan pengguna dengan kata kunci berupa istilah dan obat hiperlipidemia pada rentang waktu tahun 2020 dan selanjutnya dilakukan analisis konten secara kulalitatif. Tweet terkait hiperlipidemia yang didapat kemudian dilakukan ekstraksi dengan mengeluarkan tweet berisi iklan, berita, retweet serta konten diluar kesehatan agar mendapat persepsi dari pengguna secara utuh. Kami mengidentifikasin 1572 tweet terkait hiperlipidemia dengan 1.246 tweet (79.26%) berasal dari sudut pandang orang pertama, 156 tweet (9.92%)berasal dari sudut pandang orang kedua,114 tweet (7.25%) berasal dari tenaga kesehatan dan 56 tweet (3.56%) lain- lain. Kami mengidentifikasi 8 tema terkait hiperlipidemia yakni mengenai gejala sebanyak 120 tweet (7.69%), obat 153 tweet (9.80%), komplikasi 156 tweet (9.99%), biaya 19 tweet (1.22%), kebijakan pemerintah 16 tweet (1.02%), gaya hidup 649 tweet (41.58%), lain- lain 79 tweet (5.06%) dan tidak diketahui sebanyak 367 tweet (23.51%). Twitter dapat menjadi sumber informasi kesehatan, sarana komunikasi, jaringan tenaga kesehatan dan media promosi kesehatan. Penilaian persepsi dan sentimen masyarakat terhadap permasalahan kesehatan bisa dilakukan sebagai upaya merumuskan strategi dan kebijakan promosi kesehatan secara tepat sasaran.
Hubungan Hemoglobin dengan Kreatinin pada Penderita Diabetes Melitus
Authors: Suprihatin Putri Pamungkas Tika , Saroh Dewi 
Published: July 2024

Latar Belakang: Diabetes melitus (DM) merupakan salah satu penyakit yang tidak ditularkan (non communicable disease) dan sering ditemukan di masyarakat seluruh dunia. Diabetes melitus merupakan penyakit kronik dan dapat menimbulkan komplikasi, salah satunya adalah penurunan fungsi ginjal. Anemia merupakan komplikasi Diabetes melitus khususnya jika disertai gangguan renal. Anemia ditandai dengan penurunan hemoglobin dan gangguan renal dapat ditandai dengan peningkatan kreatinin. Tujuan: Tujuan dari penelitian ini adalah untuk mengetahui adanya hubungan antara kadar hemoglobin dengan kreatinin pada penderita Diabetes melitus. Metode: Metode penelitian ini adalah analitik korelasi dengan menggunakan pendekatan Cross Sectional. Penelitian ini dilakukan di Prodia Lampung dengan jumlah sampel yang digunakan 30 pasien Diabetes melitus pada tahun 2023. Analisis data menggunakan teknik analisis uji korelasi. Hasil: Setelah dilakukan penelitian terhadap 30 responden pasien Diabetes melitus diperoleh hasil signifikansi yaitu sebesar p=0,044. Nilai koefisien korelasi sebesar -0.370. Berdasarkan analisis menggunakan uji Spearman. menunjukkan nilai sig. (2-tailed) adalah sebesar 0.044 (p <0,05) menunjukkan adanya hubungan signifikan antara kadar hemoglobin dengan kreatinin pada penderita Diabetes melitus. Nilai koefisien korelasi sebesar -0.370 menunjukkan bahwa terdapat hubungan negatif antara kadar hemoglobin dengan kreatinin pada penderita Diabetes melitus dengan tingkat hubungan “Lemah” yang berarti semakin tinggi nilai kadar kreatinin , kadar hemoglobin pun akan semakin rendah. Kesimpulan: Dari hasil penelitian ini dapat diketahui bahwa terdapat hubungan antara kadar hemoglobin dengan kreatinin pada penderita diabetes melitus di Prodia Lampung.
Studi Kasus Asuhan Kebidanan Komprehensif di PMB Winanti, S.Tr.,Keb Kota Palangka Raya
Authors: Alestari Rena Oki , Kumala Desi , Devitasari Ivana , Baringbing Eva Prilelli 
Published: July 2024

Latar belakang : Asuhan kebidanan komprehensif adalah asuhan yang diberikan oleh bidan dari mulai masa kehamilan, persalinan, bayi baru lahir, nifas dan penggunaan KB yang bertujuan untuk memberikan pelayanan yang berkualitas untuk mencegah terjadinya kematian ibu dan anak. Tujuan penelitian: Mampu melakukan asuhan kebidanan komprehensif Pada Ny. S Di PMB Winanti, S.Tr.Keb Kecamatan Jekan Raya Kota Palangka Raya menggunakan pendekatan manajemen kebidanan 7 langkah varney dan SOAP. Metode : jenis penelitian adalah case study dengan menggambarkan asuhan kebidanan komprehensif pada Ny. S di PMB Winanti, S.Tr.Keb Kecamatan Jekan Raya Kota Palangka Raya. Subjek penelitian adalah Ny. S Usia kehamilan 37 minggu. Penelitian menggunakan variabel bebas, lokasi di PMB Winanti, S.Tr.Keb pada Maret - Agustus 2023. Hasil penelitian dianalisis menggunakan pendekatan manajemen asuhan 7 langkah varney dan pendokumentasian menggunakan SOAP. Hasil: Asuhan Kebidanan Komprehensif pada Ny. S di PMB Winanti, S.Tr.Keb Kecamatan Jekan Raya Kota Palangka Raya dilakukan mulai dari kehamilan trimester III, dengan kunjungan kehamilan sebanyak 4 kali, kunjungan persalinan 1 kali, kunjungan bayi baru lahir 3 kali, kunjungan nifas 4 kali, pelayanan keluarga berencana 1 kali, dan pendokumentasian asuhan kebidanan komprehensif dalam bentuk SOAP. Kesimpulan: Asuhan Kebidanan komprehensif pada Ny. S G2P1A0 Usia 30 Tahun mendapatkan hasil fisiologis yang baik dan normal
Uji Efektivitas Ekstrak Daun Sungkai (Peronema Canescens Jack.) dari Desa Petuk Katimpun Kalimantan Tengah Sebagai Analgetik Terhadap Tikus Putih Jantan (Rattus Norvegicus)
Authors: Rahayu Eria Wienty , Nastiti Kunti , Aryzki Saftia 
Published: July 2024

Latar Belakang: Sungkai (Peronema Canescens Jack.) merupakan salah satu tanaman obat yang digunakan masyarakat suku Dayak untuk mengobati nyeri. Tujuan: Mengetahui efektivitas ekstrak daun sungkai (Peronema Canescens Jack.) dari Desa Petuk Katimpun Kalimantan Tengah sebagai analgetik dengan berbagai konsentrasi terhadap tikus putih jantan (Rattus Norvegicus). Metode: Menggunakan rancangan true experimental. Sampel sebanyak 30 ekor tikus putih jantan dibagi menjadi 6 kelompok, yaitu kelompok kontrol negatif Na CMC 0,5%, kelompok kontrol positif natrium diklofenak, dan kelompok ekstrak etanol daun sungkai dengan dosis 100, 200, 300, dan 400 mg/kgBB. Semua diberi perlakuan sesuai kelompok secara oral. Setelah 30 menit asam asetat 1% digunakan sebagai penginduksi nyeri. kemudian dilakukan pengamatan geliat sebagai ukuran efek analgesik setiap 5 menit selama 1 jam. Data yang dihasilkan dilakukan analisis SPSS dengan ANOVA dan Post Hoc Tukey HSD untuk membandingkan aktivitas analgesik antar kelompok. Hasil: Hasil pengujian statistik menunjukkan semua dosis memiliki efek sebagai analgetik pada tikus putih jantan serta memberikan efek yang signifikan tehadap kelompok kontrol negatif (p<0,05). Pada ekstrak dengan dosis 200, dan 300 mg/kgBB tidak berbeda signifikan terhadap kontrol positif (p>0,05). Dosis ekstrak 400 mg/kgBB memiliki efek analgetik terbaik dengan nilai signifikan (p<0,05). Simpulan: Memiliki efek analgesik dari dosis 100 mg/KgBB dan efek analgetik paling tinggi terdapat pada dosis 400 mg/kgBB.
Formulasi Sedian Gel Serum Ekstrak Etanol Bawang Dayak (Eleutherine Bulbosa (Mill.) Urb) Sebagai Antibakteri
Authors: Tri Elin , Aldila Silvy , Kalsum Ummi 
Published: July 2024

Bawang Dayak memiliki manfaat untuk mengatasi berbagai penyakit kulit termasuk jerawat (Ardhany et al., 2019). Gel serum mempunyai zat aktif konsentrasi tinggi dan viskositas rendah mudah menyerap pada kulit. Ekstrak etanol bawang Dayak diformulasikan dengan konsentrasi F1 (5%), F2 (10%) dan F3 (15%). Gel serum dibuat dan diujikan karakteristik fisik Hasil pengamatan karakteristik fisik dengan parameter homogenitas, organoleptis, pH, daya debar, daya lekat, dan viskositas telah memenuhi persyaratan sediaan gel serum.
Mathematical-model Analysis of the Potential Exposure to Lead, Zinc and Iron Emissions from Consumption of Premium Motor Spirit in Nigeria
Authors: Elehinafe Francis B. , Orupete Orirome O. , Adisa Hassan A. , Lasebikan Oluseye L. 
Published: July 2024

Environmental pollution has been on the increase due to emission from vehicles using fossil fuels. This research investigated the exposure of air, soil and water bodies to trace metal emissions: Pb, Zn and Fe, as a result of the consumption of premium motor spirit (PMS) in Nigeria. The exposure of air, soil, and water bodies to these emissions also lead to exposure of humans, food and animals to the emissions. This was done to estimate the emission rates, emission rate per capita, and emission rates per land areas (or land distribution). The results showed that: the annual emission rates ranged between 4.66 kg/y for Pb in 2012 in Jigawa State and 5.050∙103 kg/y for Fe in 2015 in Lagos State; the emission rates per capita ranged between 0.52∙10−6 kg/(y∙person) for Pb in 2012 in Kwara State and 2.33∙10−3 kg/(y∙person) and this was recorded in Lagos State in the year 2015; while the rate per land area ranged between 0.093∙10−3 kg/(y∙km2) for Pb in 2012 in Taraba State and 1.38 kg/(y∙km2) for Fe in 2015 in Lagos State. Results showed that residents of Lagos are at the highest risk of trace metal poisoning because they had the highest emission rates per capita, followed by Abuja, Osun, and Ogun. The states at the lowest risk are Yobe and Taraba, with Yobe as the lowest. It is recommended that regulations concerning the trace metal contents of fuels imported and distributed in Nigeria should be created and implemented to curb these risks.
Simulação clínica na educação em enfermagem para o atendimento de queimaduras: Revisão integrativa
Authors: Dziombra André Gustavo , Viana Leyniciane Bragel , Cabral Eduarda Bopko , Bucco Marcia 
Published: July 2024

Objetivo: Identificar na literatura científica o uso da simulação como ferramenta educativa para estudantes de enfermagem no atendimento de queimaduras. Método: Revisão integrativa realizada pela busca na base de dados do LILACS, BDENF, e Google Acadêmico, no período de novembro a dezembro de 2023, utilizando o software Microsoft Excel como ferramenta de gestão dos dados. Resultados: Inicialmente, foram identificados 311 artigos e apenas 2 artigos que atenderam os critérios estabelecidos para inclusão foram utilizados nesta revisão. A relevância da aplicação da simulação clínica no ensino de estudantes de enfermagem abordando a temática de queimaduras, é destacada nos artigos selecionados junto com o relato de alunos abordando a satisfação com a experiência e benefícios da utilização da ferramenta de simulação. Conclusão: A síntese das evidências encontradas fortalece que a prática da simulação é um método eficaz para o ensino de estudantes de enfermagem no cuidado às pessoas com lesões por queimaduras.
A rare case of a vascular benign tumor in oral cavity – Case report
Authors: Morais Thayná Melo de Lima , Kitakawa Dárcio , Peralta Felipe da Silva , Gonçalves Jussara Maria , Perrone Júnior Lineu , Carvalho Luis Felipe das Chagas e Silva de 
Published: July 2024

Leiomyomas are benign tumors arising from smooth muscle and can be classified as solid, epithelioid, and vascular leiomyoma (angioleiomyoma). Angioleiomyoma frequently occurs on the skin. Due to the lack of smooth muscle in the oral cavity, this tumor is rarely located in the mouth. This study aims to present a rare case of a 36-year-old woman with a painless submucosal nodule in the left cheek mucosa, measuring approximately 2 cm x 1 cm, with 5-years of evolution. Morphological and histochemical examination evidenced the proliferation of smooth muscle around the blood vessels of various calibers. The diagnosis of angioleiomyoma was confirmed, the tumor was surgically removed, and the patient had no further complications after 9-months of follow-up. The diagnosis of oral angioleiomyoma is challenging since this tumor is rare and can mimic or transform into malignancy. For this reason, histological examination in association with immunohistochemical is invaluable to establishing an accurate diagnosis and delivering suitable treatment.
Pengenalan Enterpreneur Perikanan Bagi Siswa: Pengabdian Budidakdamber di SMA Muhammadiyah Al-Amin Sorong
Authors: Ratna  , Fahrizal Ahmad , Nurfin Moha  , Sulfiana  , Sufardin  , Neneng Suarno Kalidi  , Ameilany Dwi Anjani  , Sherlie G.L.Weyai  , Putri Firda Y. Lestari  , Muhammad Jufri Pusung  , Jumria Saet  , Charles Y. Konjol  , Darwin K. Inggamer  
Published: July 2024

Tujuan pelaksanaan pengabdian kepada masyarakat di SMA Muhammadiyah Al-AMin, Kota Sorong (SMAMINSO) adalah sebagai sarana peningkatan kemampuan siswa melalui penyediaan pangan guna mengenalkan serta menumbuhkan minat akan entrepreneur di bidang perikanan dalam bentuk pemberian pengetahuan dan pemahaman kepada Masyarakat dalam hal ini Siswa SMAMINSO tentang Budidaya Ikan dalam Ember (BUDIKDAMBER). Metode yang digunakan ialah metode ceramah dan demonstrasi bersama siswa SMAMINSO, Kota Sorong tentang cara membudidayakan ikan dan sayuran dalam satu wadah sederhana guna menumbuhkembangkan minat enterprenur perikanan serta ketahanan pangan dalam skala kecil. Hasil pelaksanaan PkM ini adalah siswa SMAMINSO, Kota Sorong dapat mengetahui cara membudidayakan ikan dan sayuran menggunakan media ember bervollume 80-liter sehingga dapat menumbuhkembangkan jiwa enterprenur perikanan serta meningkatkan ketahanan pangan di lingkungan keluarga siswa SMAMINSO.
Surgical treatment of traumatic iridodialysis with simultaneous implantation of a toric intraocular lens in a patient with aphakia. A clinical case study
Authors: Shamratov R. Z. , Ramazanova L. Sh. , Napylova O. A. , Arustamyan Zh. K. , Kirevnina E. V. 
Published: July 2024

Introduction. Iridodialysis refers to a localized detachment occurring at the attachment site of the iris to the ciliary body. This condition is often the most severe consequence of ocular trauma, leading to discomfort, decreased visual quality, and diplopia. Conventional corrective approaches typically induce astigmatism, thereby compromising the functional results of the operation.Purpose: to assess the effectiveness of an innovative surgical approach for traumatic iridodialysis that incorporates the one-time implantation of a toric intraocular lens in patients with prior unsuccessful cataract surgeries.Case description. A patient reported significant cosmetic and visual disturbances including reduced visual acuity, photophobia, and visual discomfort in the right eye, following an earlier complicated cataract surgery that did not involve an intraocular lens implant. Our treatment strategy utilized a minimally invasive technique for the simultaneous implantation of the intraocular lens and closed iridoplasty.Conclusions. The surgical approach provided rapid and complete rehabilitation, yielding high clinical and functional outcomes, including the restoration of visual acuity and the resolution of the patient’s cosmetic concerns.
Vitelliform subretinal deposits: shared pathogenesis and clinical diversity
Authors: Semenova N. S. , Pedanova E. K. 
Published: July 2024

Since its initial description, Best vitelliform macular dystrophy has been strongly linked to characteristic retinal lesions—subretinal yellowish accumulations, with a hyperreflective structure on optical coherence tomography, situated above the retinal pigment epithelium layer. However, research on this topic remains scarce. It is now recognized that, within the common pathophysiological mechanism of vitelliform lesion formation, this process may contribute to the pathogenesis of a broad spectrum of both genetic and acquired conditions.The purpose of this review is to update our understanding of genetically determined and acquired retinal diseases associated with the formation of such lesions.Materials and methods. analysis of scientific publications from databases including PubMed, ScienceDirect, and Cyberleninka was conducted. The review encompasses 16 studies, predominantly from the past decade.Results. Advances in instrumental and genetic diagnostics have revealed that vitelliform subretinal changes are not exclusive to Best disease but serve as another biomarker, indicating disruption in the metabolism of outer retinal layers. It is hypothesized that, irrespective of etiology, the primary triggering factor for lesion formation is the disjunction of outer segments of photoreceptors and impairment of phagocytic function in retinal pigment epithelial cells. This article presents a contemporary perspective on the presumed etiology and pathophysiology of vitelliform lesions, alongside clinical characteristics, manifestations, and prognosis of diseases associated with this phenomenon. Diseases with identified genetic mutations in the BEST1 gene (Bestrophinopathies) and PRPH2, as well as common acquired conditions like age-related macular degeneration and vitreoretinal traction syndrome, are discussed.Conclusions. The provided clinical characteristics, supported by multimodal visualization, are expected to aid in differential diagnosis and prognostication of the disease course.
Implantation of phakic intraocular lenses in patients with stabilized keratoconus
Authors: Kazantsev A. D. , Kostenev S. V. , Azhdarova L. V. , Slonimskiy A. Yu. 
Published: July 2024

To date, extensive experience has been accumulated in the correction of high myopia and myopic astigmatism through the implantation of additional negative lenses (phakic intraocular lenses). However, the use of this method in patients with anatomically altered corneas due to keratoconus remains unresolved.Purpose: to assess the effectiveness and safety of correcting high myopia combined with myopic astigmatism by implanting phakic intraocular lenses in patients with stabilized keratoconus at stages 1–2.Materials and methods. The study encompassed results from 27 surgeries involving the implantation of phakic intraocular lenses in patients with high myopia and myopic astigmatism (12.63 ± 4.25 D). These patients had thin corneas and were diagnosed with stage 1–2 keratoconus after undergoing corneal collagen crosslinking treatment – this constituted the main group. The control group comprised 35 surgeries performed on patients with subclinical non-progressive keratoconus (Forme Fruste). All participants underwent evaluations for visual acuity dynamics and refractive stability of spherical and cylindrical components before surgery, immediately post-surgery, and then at 1, 6, and 12 months after implantation. Additional assessments included intraocular pressure measurements, gonioscopy, ultrasonic echobiometry, ultrasonic ophthalmoscopy, biomicroscopy, ophthalmoscopy, endothelial microscopy, vision character and stereopsis determination, ultrasound biomicroscopy, anterior segment optical coherence tomography, electrophysiological studies, and statistical analysis. An IPCL (a type of phakic intraocular lenses made from hydrophilic acrylic) was implanted, capable of correcting myopia up to 30 D and astigmatism up to 10 D.Results. All patients achieved high uncorrected visual acuity 0.86 ± 0.11. Astigmatism correction was successful in 96% of cases. The average postoperative vault – the distance from the back surface of the phakic intraocular lenses to the anterior lens capsule – was 527.5 ± 40.27 μm (range 460–600 μm), and the intraocular pressure was 11.7 ± 2.08 mm Hg. There was a minor decrease in corneal endothelial cell count from 2599 ± 157.3 to 2375 ± 125.3 cells/mm² in the first group and from 2614 ± 104.8 to 2375 ± 43.3 cells/mm² in the second group respectively (p > 0.05), which falls within the acceptable loss range of 4–7% from preoperative values for both groups. Throughout the observation period, there were no cases of cataract development, pigmentary glaucoma, pupillary block, or other vision-threatening complications.Conclusions. Implantation of phakic intraocular lenses in patients with early-stage stabilized keratoconus and subclinical non-progressive keratoconus provides an effective and practically safe means of correcting high myopia and astigmatism.
Hemicentin-1 is an essential extracellular matrix component during tooth root formation by promoting mesenchymal cells differentiation
Authors: Cui Yujia , Li Chuwen , Wang Hanyang , Li Lei , Xie Jing , Zhou Xuedong , Zhang Hai , Sun Jianxun 
Published: July 2024

Introduction: Root dentin formation is an important process in tooth development. We tried to identify potential genes that regulate root dentin formation which could be potentially used for the regeneration and repair of defective or damaged dental roots.Methods: Tissues harvested from the labial and lingual sides of mouse incisors were used for microarray analysis. Gene ontology (GO) analysis of differentially expressed genes indicated the critical role of extracellular matrix in the discrepancy of dentin formation between root and crown, for which hemicentin-1 (Hmcn1) was selected as the target gene. Single-cell RNA sequencing analysis the expression pattern of Hmcn1 at different developmental stages in mouse molars. The spatiotemporal expression of HMCN1 in mouse incisors and molars was detected by immunohistochemical staining. The functions of HMCN1 in human dental pulp cells, including proliferation, differentiation and migration, were examined in vitro by CCK8 assay, BrdU assay, wound-healing assay, ALP staining and alizarin red staining, respectively.Results: It was showed that HMCN1 expression was more pronounced in papilla-pulp on the root than crown side in mouse incisors and molars. In vitro experiments presented inhibited dentinogenesis and migration after HMCN1-knockdown in human dental pulp cells, while there was no significant difference in proliferation between the HMCN1-knockdown group and control group.Discussion: These results indicated that HMCN1 plays an important role in dentinogenesis and migration of pulp cells, contributing to root dentin formation.