bluuebunny/crossref_metadata_2025_split huggingface dataset:
Heart Rate Control in Patients With Chronic Atrial Fibrillation and Heart Failure
Authors: Silvet Helme , Hawkins Lee Ann , Jacobson Alan K. 
Published: September 2012

©2012 Wiley Periodicals, Inc.The goal of this study was to determine whether aggressive heart rate (HR) control in patients with both chronic atrial fibrillation (AF) and heart failure (HF) is associated with improved outcomes. HR control is one of the mainstays in management of patients with AF. However, rate control can be challenging in patients with HF. This study was designed as an interventional clinical trial, using patients with chronic AF and left ventricular systolic dysfunction with left ventricular ejection fraction ≤40% (n=20) as their own controls. Intervention consisted of increasing doses of metoprolol succinate to achieve target resting HR <70 beats per minute. Clinical data were collected at baseline and after intervention, with paired t test used to evaluate statistically significant change. After 3 months of intervention, average resting HR decreased from 94±14 beats per minute to 85±12 beats per minute. Average metoprolol succinate dose at the end of the study was 121 mg. None of the outcomes improved significantly after the intervention, including exercise tolerance (meters walked on 6‐minute walk test 326±83 vs 330±86), quality of life (Minnesota Living With Heart Failure Questionnaire score of 42.5±19 vs 38±21), and brain natriuretic peptide (242±306 pg/mL vs 279±395 pg/mL). Aggressive HR control was difficult in this group of patients with chronic AF and HF due to patient intolerance of increasing doses of β‐blockade, and not associated with improved outcomes. Further studies are needed to establish guidelines for target HR in patients with chronic AF who also have significant HF.
The relationship between energy consumption, energy prices and economic growth: case study (OPEC countries)
Authors: Hossein Abbasinejad , Yazdan Gudarzi Farahani , Ehsan Asghari Ghara 
Published: September 2012

AbstractThis paper studies the causal relationships between energy consumption and economic growth for OPEC countries using cointegration and error‐correction modelling techniques. The results indicate that in the short run, the Granger causality runs from income to energy consumption for Iran, Iraq, Qatar, United Arab Emirates and Saudi Arabia, while for the rest of the Organization of Petroleum Exporting Countries (OPEC) countries, the reverse is true, i.e. the Granger causality runs from energy consumption to income. However, in the long run, there is not any Granger causality relationship for all the OPEC countries. In the case of Qatar and the Saudi Arabia and Nigeria, energy, economic growth and prices are not mutually causal. Results show, that even for these countries, which the energy consumption has an effect on economic growth, the effect is very minimal. The direction of causation between energy consumption and economic growth has significant policy implications. If there exists unidirectional Granger causality running from income to energy, it may be implied that energy conservation policies may be implemented with little adverse or no effects on economic growth. In the case of negative causality running from economic growth to energy, economic growth could rise if energy conservation policy were to be implemented. In other words, if unidirectional causality runs from energy consumption to income, reducing energy consumption could lead to a fall in economic growth. One can conclude that for all of the OPEC countries, the theory of resource curse holds. Hence, substantial energy consumption is not likely to bring about significant economic growth but an increase in CO2 emissions. In this regard, it is very important for those low‐income OPEC countries to adopt appropriate energy policies in order to promote their economic growth.
Adaptive radiotherapy for muscle‐invasive bladder cancer: Optimisation of plan sizes
Authors: Kuyumcian Arman , Pham Daniel , Thomas Jessica M , Law Alastair , Willis David , Kron Tomas , Foroudi Farshad 
Published: September 2012

AbstractIntroductionPlan‐of‐the‐day adaptive radiotherapy (ART) that has not been optimally designed may result in inefficient plan sizes. This can lead to unused plans, which may potentially reduce overall conformality. We compared two methods of individualising ART plan sizes for muscle‐invasive bladder cancer to determine which provides a more balanced distribution of plan selections.MethodsTwenty‐seven previously treated patients had small, medium and large ART plans generated from CTV contours on the simulation CT and initial cone beam CTs (CBCT). In the original clinical method, the smallest plan was based on the smallest CTV, while the experimental method used the Boolean summation of the two smallest CTVs. The large plan was identical in both methods. The medium plans were created midway between small and large CTVs. Credentialed treatment staff performed plan selection clinically for the original plans and retrospectively for the experimental plans.ResultsA total of 646 CBCTs from 26 patients were included. The small, medium and large adaptive CTVs, and the conventional CTV, were used 29.7%, 45.4%, 22.0% and 2.9% of the time, respectively, compared to the previous 9.8%, 49.2%, 39.5% and 1.5%. The differences were significant between previous and new CTV (small), and CTV (large).ConclusionsThe new design method resulted in the three adaptive CTV choices being selected more evenly, however, a reduction in a surrogate for normal tissue irradiation was not observed.
Conflicts Associated with Exempt Wells: A Spaghetti Western Water War
Authors: Vinett Megan A. , Jarvis Todd 
Published: September 2012

Abstract:The saga over exempt wells in the western United States and Canada epitomizes a new type of water conflict – a spaghetti‐western water war. The political melodrama stars local governments to serve as sheriff of water‐supply planning duties. Exempt wells number in the millions, and herding the growing numbers is testing the mettle of the states and provinces responsible for the management, allocation, and protection of natural resources. The separation of laws governing ground water and surface water, coupled with changes in geography and geology within a jurisdiction, compound the administrative riddle and give rise to a broad spectrum of conflicts, from differing interpretations of hydrogeologic data, economic impacts associated with increasing the herd, to differing identities associated with the use of ground water from the exempt wells. Despite the political melodrama of exempt wells, there is room and willingness for other trails and paths to keep the herd intact. This paper describes the different breeds of conflicts associated with exempt wells and gives examples of how the mysterious stranger of collaborative decision making processes and water governance systems can ride into town and lead to successful water management and conflict resolution.
The Implications of Bounds v. State of New Mexico
Authors: Richardson Jesse J. , Dowell Tiffany 
Published: September 2012

Abstract:National attention has turned to a case currently pending before the New Mexico Supreme Court. Bounds v. State of New Mexico involves a facial constitutional challenge to New Mexico's domestic well statute. The Plaintiff, Horace Bounds, claims that the statute, which requires the State Engineer to issue permits to any applicants for domestic purposes, violates the constitutional provision known as the Prior Appropriation Doctrine. The decision of the Court will likely have impacts across the country and beyond the legal realm. This decision could impact the well drilling industry, economic development, and administrative agencies. Numerous other western states have similar exempt well provisions, and the decision by the New Mexico Supreme Court could well lead to litigation or pushes for changes in legislation on other states as well.
Relocating from out‐of‐area treatments: service users' perspective
Authors: RAMBARRAN D. D. 
Published: September 2012

Accessible summary

In the UK, there are growing concerns about the impact of ‘out‐of‐area treatments’ (OATs) on mental health service users, both clinically and financially. In addition to being costly to the National Health Service (NHS) and local social care authorities, service users placed out of area have been socially dislocated and in some cases over supported.

Prompted by these concerns, a project was set up in one inner London Borough, to review and where appropriate repatriate mental health service users they had placed outside the local area. This study explored the experiences and impact of these relocations from service users' perspectives.

Increased autonomy was the most commonly reported positive outcome, which was welcomed by all; however, many service users also reported feeling lonely in their new local placements. Five out of seven were pleased with their increased contact with family and most concluded that generally, relocation enhanced their quality of life.

A number of NHS Trusts are considering the implementation of similar approaches to review their ‘OATs’ clients; hence the favourable outcomes reported here and elsewhere are likely to encourage this. However, it is essential that these be considered alongside the support required for service users to reconnect positively with their families, in addition to adjusting to more independent living.

AbstractAsylum closures over recent decades resulted in mental health services being increasingly sited in the community. However, under provision of highly supported accommodation led to service users being placed away from their local area in ‘out‐of‐area treatments’ (OATs). OATs have raised major concerns in relation to enabling service users' recovery, owing to limitations in promoting autonomy, social dislocation and costs. In 2004, an OATs project was set up in a London Borough to address these concerns. In the first 4 years, the project succeeded in relocating 22 service users to less restrictive environments locally. This study aims to explore the outcome of relocation from service users' perspective. A qualitative methodology was utilized. Semi‐structured interviews were carried out with seven service users who relocated. All seven service users shared a strong aspiration for independent living but there was associated loneliness. Five welcomed increased contact with family and friends, but lacked social confidence, inhibiting social inclusion. Service users with long‐term and consistent care managers were more able to address fears. Five out of seven service users concluded that relocation increased their autonomy thus enhanced their quality of life.
Love the one you're with: proximity determines paternity success in the barnacle Tetraclita rubescens
Authors: Kelly Morgan W. , Grosberg Richard K. , Sanford Eric 
Published: September 2012

AbstractA species' mating system sets limits on the strength of sexual selection. Sexual selection is widespread in dioecious species, but is less well documented in hermaphrodites, and may be less important. We used four highly polymorphic microsatellite markers to assign paternity to broods of the hermaphroditic eastern Pacific volcano barnacle Tetraclita rubescens. These data were used to describe the species' mating system and to examine factors affecting male reproductive success. Tetraclita can sire broods over distances of 11.2 cm, but proximity to the sperm recipient had a highly significant effect on the probability of siring success. There was no effect of body size or the mass of male reproductive tissues on siring success. Broods showed relatively low frequencies of multiple paternity; even at high densities, 75% of broods had only one father. High frequencies of single‐paternity broods imply either that this species does not compete via sperm displacement, or that sperm displacement is extremely effective, potentially explaining the lack of a positive relationship between male investment and paternity. In addition, there was low variance in siring success among individuals, suggesting a lack of strong sexual selection on male traits. Low variance among sires and the strong effect of proximity are probably driven by the unusual biology of a sessile copulating species.
Immunoglobulin G profile in hyperacute rejection after multivisceral xenotransplantation
Authors: Galvao Flavio H. F. , Soler Wangles , Pompeu Eduardo , Waisberg Daniel R. , Mello Evandro S. D. , Costa Anderson C. L. , Teodoro Walcy , Velosa Ana P. , Capelozzi Vera L. , Antonangelo Leila , Catanozi Sergio , Martins Alessandro , Malbouisson Luiz M. S. , Cruz Ruy J. , Figueira Estela R. , Filho Joel A. R. , Chaib Eleazar , D′Albuquerque Luiz A. C. 
Published: September 2012

Galvao FHF, Soler W, Pompeu E, Waisberg DR, Mello ES, Costa ACL, Teodoro W, Velosa AP, Capelozzi VL, Antonangelo L, Catanozi S, Martins A, Malbouisson LMS, Cruz RJ, Figueira ER, Filho JAR, Chaib E, D′Albuquerque LAC. Immunoglobulin G profile in hyperacute rejection after multivisceral xenotransplantation. Xenotransplantation 2012; 19: 298–304. © 2012 John Wiley & Sons A/S.Abstract:  Introduction:  Xenotransplantation is a potential solution for the high mortality of patients on the waiting list for multivisceral transplantation; nevertheless, hyperacute rejection (HAR) hampers this practice and motivates innovative research. In this report, we describe a model of multivisceral xenotransplantation in which we observed immunoglobulin G (IgG) involvement in HAR.Methods:  We recovered en bloc multivisceral grafts (distal esophagus, stomach, small intestine, colon, liver, pancreas, and kidneys) from rabbits (n = 20) and implanted them in the swine (n = 15) or rabbits (n = 5, control). Three hours after graft reperfusion, we collected samples from all graft organs for histological study and to assess IgG fixation by immunofluorescence. Histopathologic findings were graded according to previously described methods.Results:  No histopathological features of rejection were seen in the rabbit allografts. In the swine‐to‐rabbit grafts, features of HAR were moderate in the liver and severe in esophagus, stomach, intestines, spleen, pancreas, and kidney. Xenograft vessels were the central target of HAR. The main lesions included edema, hemorrhage, thrombosis, myosites, fibrinoid degeneration, and necrosis. IgG deposition was intense on cell membranes, mainly in the vascular endothelium.Conclusions:  Rabbit‐to‐swine multivisceral xenotransplants undergo moderate HAR in the liver and severe HAR in the other organs. Moderate HAR in the liver suggests a degree of resistance to the humoral immune response in this organ. Strong IgG fixation in cell membranes, including vascular endothelium, confirms HAR characterized by a primary humoral immune response. This model allows appraisal of HAR in multiple organs and investigation of the liver’s relative resistance to this immune response.
Detailed high‐accuracy megavoltage transmission measurements: A sensitive experimental benchmark of EGSnrc
Authors: Ali E. S. M. , McEwen M. R. , Rogers D. W. O. 
Published: September 2012

Purpose:There are three goals for this study: (a) to perform detailed megavoltage transmission measurements in order to identify the factors that affect the measurement accuracy, (b) to use the measured data as a benchmark for theEGSnrc system in order to identify the computational limiting factors, and (c) to provide data for others to benchmark Monte Carlo codes.Methods:Transmission measurements are performed at the National Research Council Canada on a research linac whose incident electron parameters are independently known. Automated transmission measurements are made on‐axis, down to a transmission value of ∼1.7%, for eight beams between 10 MV (the lowest stable MV beam on the linac) and 30 MV, using fully stopping Be, Al, and Pb bremsstrahlung targets and no fattening filters. To diversify energy differentiation, data are acquired for each beam using low‐Z and high‐Z attenuators (C and Pb) and Farmer chambers with low‐Z and high‐Z buildup caps. Experimental corrections are applied for beam drifts (2%), polarity (2.5% typical maximum, 6% extreme), ion recombination (0.2%), leakage (0.3%), and room scatter (0.8%)—the values in parentheses are the largest corrections applied. The experimental setup and the detectors are modeled using EGSnrc, with the newly added photonuclear attenuation included (up to a 5.6% effect). A detailed sensitivity analysis is carried out for the measured and calculated transmission data.Results:The developed experimental protocol allows for transmission measurements with 0.4% uncertainty on the smallest signals. Suggestions for accurate transmission measurements are provided. Measurements andEGSnrc calculations agree typically within 0.2% for the sensitivity of the transmission values to the detector details, to the bremsstrahlung target material, and to the incident electron energy. Direct comparison of the measured and calculated transmission data shows agreement better than 2% for C (3.4% for the 10 MV beam) and typically better than 1% for Pb. The differences can be explained by acceptable photon cross section changes of ⩽0.4%.Conclusions:Accurate transmission measurements require accounting for a number of influence quantities which, if ignored, can collectively introduce errors larger than 10%. Accurate transmission calculations require the use of the most accurate data and physics options available inEGSnrc, particularly the more accurate bremsstrahlung angular sampling option and the newly added modeling of photonuclear attenuation. Comparison between measurements and calculations implies that EGSnrc is accurate within 0.2% for relative ion chamber response calculations. Photon cross section uncertainties are the ultimate limiting factor for the accuracy of the calculated transmission data (Monte Carlo or analytical).
Whole-Genome Shotgun Sequence of Rhodococcus Species Strain JVH1
Authors: Brooks Shannon L. , Van Hamme Jonathan D. 
Published: September 2012

ABSTRACTHere we present a whole-genome shotgun sequence ofRhodococcusspecies strain JVH1, an organism capable of degrading a variety of organosulfur compounds. In particular, JVH1 is able to selectively cleave carbon-sulfur bonds within alkyl chains. A large number of oxygenases were identified, consistent with other members of the genus.
Genomic Insights into the Emerging Human Pathogen Mycobacterium massiliense
Authors: Tettelin Hervé , Sampaio Elizabeth P. , Daugherty Sean C. , Hine Erin , Riley David R. , Sadzewicz Lisa , Sengamalay Naomi , Shefchek Kent , Su Qi , Tallon Luke J. , Conville Patricia , Olivier Kenneth N. , Holland Steven M. , Fraser Claire M. , Zelazny Adrian M. 
Published: September 2012

ABSTRACT

Mycobacterium massiliense
(
Mycobacterium abscessus
group) is an emerging pathogen causing pulmonary disease and skin and soft tissue infections. We report the genome sequence of the type strain CCUG 48898.
Complete Genome Sequence of Mycoplasma wenyonii Strain Massachusetts
Authors: dos Santos Andrea P. , Guimaraes Ana M. S. , do Nascimento Naíla C. , SanMiguel Phillip J. , Messick Joanne B. 
Published: September 2012

ABSTRACTMycoplasma wenyoniiis a hemotrophic mycoplasma that causes acute and chronic infections in cattle. Here, we announce the first complete genome sequence of this organism. The genome is a single circular chromosome with 650,228 bp and G+C% of 33.9. Analyses ofM. wenyoniigenome will provide insights into its biology.
Draft Genome Sequence of Flavobacterium sp. Strain F52, Isolated from the Rhizosphere of Bell Pepper (Capsicum annuum L. cv. Maccabi)
Authors: Kolton Max , Green Stefan J. , Harel Yael Meller , Sela Noa , Elad Yigal , Cytryn Eddie 
Published: September 2012

ABSTRACT

Here we report the draft genome sequence of
Flavobacterium
sp. strain F52, isolated from the rhizosphere of bell pepper (
Capsicum annuum
L. cv. Maccabi).
Flavobacterium
spp. are ubiquitous in the rhizospheres of agricultural crops; however, little is known about their physiology. To our knowledge, this is the first published genome of a root-associated
Flavobacterium
strain.
Genome Sequence of Pseudomonas stutzeri Strain JM300 (DSM 10701), a Soil Isolate and Model Organism for Natural Transformation
Authors: Busquets Antonio , Peña Arantxa , Gomila Margarita , Bosch Rafael , Nogales Balbina , García-Valdés Elena , Lalucat Jorge , Bennasar Antoni 
Published: September 2012

ABSTRACT

Pseudomonas stutzeri
strain JM300 (DSM 10701) is a denitrifying soil isolate and a model organism for natural transformation in bacteria. Here we report the first complete genome sequence of JM300, the reference strain of genomovar 8 for the species.
Draft Genome Sequence of Citreicella aestuarii Strain 357, a Member of the Roseobacter Clade Isolated without Xenobiotic Pressure from a Petroleum-Polluted Beach
Authors: Suarez-Suarez L. Y. , Brunet-Galmes I. , Piña-Villalonga J. M. , Christie-Oleza J. A. , Peña A. , Bennasar A. , Armengaud J. , Nogales B. , Bosch R. 
Published: September 2012

ABSTRACT

Citreicella aestuarii
357 is a member of the
Roseobacter
clade that was isolated without xenobiotic pressure from an oil-polluted sand sample from the Galician coast (Spain). Its genome sequence suggests an organoheterotrophic metabolism, including a wide catabolic potential for aromatic hydrocarbons.
Complete Genome Sequence of Streptococcus pyogenes M1 476, Isolated from a Patient with Streptococcal Toxic Shock Syndrome
Authors: Miyoshi-Akiyama Tohru , Watanabe Shinya , Kirikae Teruo 
Published: September 2012

ABSTRACT

Here, we report the completely annotated genome sequence of
Streptococcus pyogenes
M1 476 isolated from a patient with streptococcal toxic shock syndrome (STSS) during pregnancy. The genome sequence will provide new insights into the mechanisms underlying STSS.
Draft Genome Sequences of Enterobacter sp. Isolate Ag1 from the Midgut of the Malaria Mosquito Anopheles gambiae
Authors: Jiang Jinjin , Alvarez Celeste , Kukutla Phanidhar , Yu Wanqin , Xu Jiannong 
Published: September 2012

ABSTRACT

An isolate of
Enterobacter
sp. was obtained from the microbial community within the gut of the
Anopheles gambiae
mosquito, a major malaria vector in Africa. This genome was sequenced and annotated. The genome sequences will facilitate subsequent efforts to characterize the mosquito gut microbiome.
Complete Genome Sequence of the Porcine Isolate Enterococcus faecalis D32
Authors: Zischka Melanie , Kuenne Carsten , Blom Jochen , Dabrowski Piotr W. , Linke Burkhard , Hain Torsten , Nitsche Andreas , Goesmann Alexander , Larsen Jesper , Jensen Lars B. , Witte Wolfgang , Werner Guido 
Published: September 2012

ABSTRACT

The complete and annotated genome sequence of
Enterococcus faecalis
D32, a commensal strain isolated from a Danish pig, suggests putative adaptation to the porcine host and absence of distinct virulence-associated traits.
Complete Genome Sequence of Avian Tembusu-Related Virus Strain WR Isolated from White Kaiya Ducks in Fujian, China
Authors: Wan Chunhe , Huang Yu , Fu Guanghua , Shi Shaohua , Cheng Longfei , Chen Hongmei 
Published: September 2012

ABSTRACT
Avian tembusu-related virus, which was first identified in China, is an emerging virus causing serious economic loss to the Chinese poultry industry. We report here the complete genome sequences of avian tembusu-related virus strain WR, isolated from a White Kaiya duck with disease characterized by an abrupt decrease in egg laying with ovarian hemorrhage, which will help in further understanding the molecular and evolutionary characteristics and pathogenesis of avian tembusu-related virus, the new flavivirus affecting ducks in Southern China.