bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Carbene Transfer — A New Pathway for Propargylic Esters in Gold Catalysis.
Authors: Lauterbach Tobias , Gatzweiler Sabrina , Noesel Pascal , Rudolph Matthias , Rominger Frank , Hashmi A. Stephen K. 
Published: March 2014

AbstractTreatment of bisalkynyl substrates (I) and (III) with catalytic amounts of AuCl results in the formation of vinyl‐substituted β‐naphthol derivatives.
ChemInform Abstract: Efficient Synthesis of Functionalized 1‐Oxo‐1‐phenyl‐2‐acetic Acids Through Ru(II)‐Catalyzed Transfer Hydrogenation.
Authors: Wang Xiaowei , Yan Yunnan , Gong Binwei , Tang Xiaobo , Li Qiu , Meng Yanqin , Xu H. Eric , Yi Wei 
Published: March 2014

AbstractA new and efficient method for the synthesis of indanylacetic acid via chemoselective transfer hydrogenation of corresponding oxoindanylideneacetic acids (I) is developed.
ChemInform Abstract: Palladacycle‐Catalyzed Methylenecyclopropanation of Bicyclic Alkenes with Propiolates.
Authors: Mo Dong‐Liang , Yuan Teng , Ding Chang‐Hua , Dai Li‐Xin , Hou Xue‐Long 
Published: March 2014

AbstractThe title reaction is only applicable to terminal propiolates.
ChemInform Abstract: Exploitation of Dual Character of CN Moiety in the Synthesis of Uniquely Decorated 3H‐Pyrroles: A Rare Observation.
Authors: Das Paramita , Ray Suman , Mukhopadhyay Chhanda 
Published: March 2014

AbstractThe approach to 3H‐pyrroles presented herein offers an unprecedented coupling which leads to the construction of the nitrogen containing ring without starting from any amine moiety.
ChemInform Abstract: Cu(II)‐Catalyzed Highly Regio‐ and Stereoselective Construction of C—C Double Bonds: An Efficient Method for the Ketonization—Olefination of Indoles.
Authors: Bao Yun‐Hong , Zhu Jia‐Yi , Qin Wen‐Bing , Kong Yu‐Bo , Chen Zheng‐Wang , Tang Shao‐Bin , Liu Liang‐Xian 
Published: March 2014

AbstractA novel method for the cross‐coupling of indoles (I) with β‐keto esters (II), (V), and (VII) using TEMPO/CuSO4 in air as oxidant is described.
ChemInform Abstract: Regiospecific Benzylation of Tryptophan and Derivatives Catalyzed by a Fungal Dimethylallyl Transferase.
Authors: Liebhold Mike , Li Shu‐Ming 
Published: March 2014

AbstractThe acceptance of benzyl diphosphate (II) as an alkyl donor by the fungal dimethylallyl transferase FgaPT2 and the regiospecific enzymatic benzylation of tryptophan and analogues are studied.
ChemInform Abstract: (R/S)‐BINOL‐α‐Phosphoryloxy Enecarbamate‐Mediated and (R/S)‐Titanium(IV) BINOLates‐Catalyzed Enantioselective Intramolecular Heck/Aza‐Diels—Alder Cycloaddition (IHADA): An Expedient Methodology.
Authors: Khan Imran A. , Saxena Anil K. 
Published: March 2014

AbstractThe conversion of o‐vinyl substituted N‐Boc‐N‐acetyl anilines to enecarbamates and subsequent Diels—Alder reaction in the presence of enantiopure BINOL as chiral source is developed.
ChemInform Abstract: Reaction of 3‐(Alken‐1‐yl)‐4,5‐dihydro‐3H‐pyrazoles with Sodium Nitrite in Acetic Acid.
Authors: Yakovlev K. V. , Khanova M. D. , Petrov D. V. , Kuleshov S. P. , Dokichev V. A. 
Published: March 2014

AbstractNitrosation of 3‐vinyldihydropyrazole (I) affords the 1‐nitrosopyrazole (II), whereas 3‐isopropenyldihydropyrazole (III) gives unexpectedly the side‐chain nitrosated derivative (IV).
ChemInform Abstract: A Sustainable Route Towards Imidazolium Building Blocks Based on Biomass Molecules.
Authors: Esposito Davide , Kirchhecker Sarah , Antonietti Markus 
Published: March 2014

AbstractA simple one‐pot protocol for the synthesis of bifunctional imidazolium compounds via three component reaction of amino acids or aliphatic amines with pyruvaldehyde and formaldehyde is developed.
ChemInform Abstract: Easy Conjugations Between Molecules via Copper‐Catalyzed Reactions of ortho‐Aromatic Diamines with Ketones.
Authors: Lu Juyou , Yang Haijun , Jin Yunhe , Jiang Yuyang , Fu Hua 
Published: March 2014

AbstractA highly efficient method for the synthesis of benzo[d]imidazole derivatives (III) (34 examples) via Cu‐catalyzed reaction of o‐phenylenediamines with ketones is developed.
ChemInform Abstract: Synthesis of Novel 1,3‐Oxazole Derivatives with Insect Growth‐Inhibiting Activities.
Authors: Guo Peng , Huang Jun‐Hai , Huang Qing‐Chun , Qian Xu‐Hong 
Published: March 2014

AbstractA series of novel asymmetrically disubstituted oxazole derivatives (IV) (20 examples) are synthesized and evaluated for their armyworm growth regulating activities.
ChemInform Abstract: Condensation of Vilsmeier Salts, Derived from Tetraalkylureas, with Amidoximes: A Novel Approach to Access N,N‐Dialkyl‐1,2,4‐oxadiazol‐5‐amines.
Authors: Su Dongshan , Duan Haifeng , Wei Zhonglin , Cao Jungang , Liang Dapeng , Lin Yingjie 
Published: March 2014

AbstractThe condensation of Vilsmeier salts and amidoximes proceeds under mild conditions to give oxadiazol derivatives.
ChemInform Abstract: An Improved Synthesis and Some Reactions of Diethyl 4‐Oxo‐4H‐pyran‐2,5‐dicarboxylate.
Authors: Obydennov Dmitrii L. , Roeschenthaler Gerd‐Volker , Sosnovskikh Vyacheslav Ya. 
Published: March 2014

AbstractCondensation of 2‐(dimethylamino)methylene‐3‐oxobutanoate with diethyl oxalate in the presence of NaH and following HCl‐promoted cyclization offers an improved synthesis of 4‐oxo‐4H‐pyran‐2,5‐dicarboxylate (IV).
ChemInform Abstract: A Selective Synthesis of 4‐Bromoisoquinoline and 4‐Bromoisoquinolone.
Authors: Zhang Hong‐Ping , Li Hong‐Yan , Xiao Hong‐Fang 
Published: March 2014

AbstractAn efficient method for the selective synthesis of 4‐bromoisoquinoline and ‐isoquinolone derivatives via Pd‐catalyzed cyclization of 2‐alkynylbenzyl azides is developed.
ChemInform Abstract: A Concise Synthesis of Indoloquinoline Skeletons Applying Two Consecutive Pd‐Catalyzed Reactions.
Authors: Boganyi Borbala , Kaman Judit 
Published: March 2014

AbstractThe synthesis of indoloquinolines from bromo‐iodoquinolines by following a two‐step strategy based on a Buchwald—Hartwig amination as a first step followed by an intramolecular Heck‐type reaction to execute the ring closure is described.
ChemInform Abstract: Two New Indole Derivatives as Anion Receptors for Detecting Fluoride Ion.
Authors: Liu Xiu‐Ming , Zhao Qiang , Li Yue , Song Wei‐Chao , Li Ya‐Ping , Chang Ze , Bu Xian‐He 
Published: March 2014

AbstractThe two new indole derivatives (III) and (IV) display highly selective response to fluoride anions in aqueous DMSO and pure DMSO medium with remarkable color and fluorescence changes.
ChemInform Abstract: Rhodium‐Catalyzed Oxidative Annulation of Sulfoximines and Alkynes as an Approach to 1,2‐Benzothiazines.
Authors: Dong Wanrong , Wang Long , Parthasarathy Kanniyappan , Pan Fangfang , Bolm Carsten 
Published: March 2014

AbstractRh‐catalyzed oxidative cyclocondensation of NH‐sulfoximines and internal alkynes provides an efficient synthesis of 1,2‐benzothiazines.
ChemInform Abstract: An Expedient Route to Dihydrothiazines, a Virtually Unknown Class of Heterocycles.
Authors: Quiclet‐Sire Beatrice , Zard Samir Z. 
Published: March 2014

AbstractUpon heating in diphenyl ether, S‐(4‐oximinoalkyl)xanthates with a secondary isopropyl or isobutyl group on the oxygen undergo a Chugaev elimination followed by ring closure onto the oxime giving dihydrothiazines, a virtually unknown class of heterocycles.
ChemInform Abstract: Amine‐Free Approach Toward N‐Toluenesulfonyl Amidine Construction: A Phosphite‐Mediated Beckmann‐Like Coupling of Oximes and p‐Toluenesulfonyl Azide.
Authors: Fleury Lauren M. , Wilson Erin E. , Vogt Monika , Fan Tiffany J. , Oliver Allen G. , Ashfeld Brandon L. 
Published: March 2014

AbstractThe reaction of oximes (I) with the chlorophosphite (II) and tosyl azide is examined resulting in the formation of N‐tosyl amidines through a Beckmann‐type process.
ChemInform Abstract: Synthesis of Tetrasubstituted α‐Aminophosphonic Acid Derivatives from Trisubstituted α‐Aminophosphonates.
Authors: Vicario Javier , Ortiz Pablo , Palacios Francisco 
Published: March 2014

AbstractAddition reaction of organometallic reagents to tertiary α‐iminophosphonates offers an efficient strategy for the preparation of quaternary α‐aminophosphonates.
ChemInform Abstract: Synthesis of Trisubstituted Alkenylstannanes Through Copper‐Catalyzed Three‐Component Coupling of Alkylboranes, Alkynoates, and Tributyltin Methoxide.
Authors: Wakamatsu Takamichi , Nagao Kazunori , Ohmiya Hirohisa , Sawamura Masaya 
Published: March 2014

AbstractThe reaction of monosubstituted ethenes with (9‐BBN)2 and subsequent Cu‐catalyzed coupling of the resulting alkylborane with acetylenic esters and Bu3SnOMe offers a stereoselective synthesis of highly functionalized vinyl stannanes.
ChemInform Abstract: Benzothiadiazole‐Based Dyes that Emit Red Light in Solution, Solid and Liquid State.
Authors: Ishi‐i Tsutomu , Sakai Miki , Shinoda Chihiro 
Published: March 2014

AbstractThe preparation and red‐light‐emitting behavior of benzothiadiazole‐tris(alkyloxy)phenylene dyes (I) are reported.
ChemInform Abstract: Two New Cytotoxic Sesquiterpenoids from Solanum lyratum.
Authors: Li Gui‐Sheng , Yao Fang , Zhang Lei , Yue Xi‐Dian , Dai Sheng‐Jun 
Published: March 2014

AbstractIn vitro, both eudesmane‐type sesquiterpenoids (I) (named solajiangxins F and G), show significant cytotoxic activity against selected cancer cells such as P‐388, HONE‐1, and HT‐29.
ChemInform Abstract: Anticancer Evaluation of Carboxamides of Furano‐Sesquiterpene Carboxylic Acids from the Soft Coral Sinularia kavarattiensis.
Authors: Venkateswarlu Yenamandra , et al. et al. 
Published: March 2014

AbstractNew furano‐sesquiterpene carboxylic acid derivatives (I) are isolated and transformed into new amide derivatives (II).
ChemInform Abstract: Pahangensin A and B, Two New Antibacterial Diterpenes from the Rhizomes of Alpinia pahangensis Ridley
Authors: Sivasothy Yasodha , Ibrahim Halijah , Paliany Audra Shaleena , Alias Siti Aisyah , Awang Khalijah 
Published: March 2014

Abstractisolation, structure elucidation and antibacterial activity
ChemInform Abstract: Nickel‐Catalyzed Arylation, Alkenylation, and Alkynylation of Unprotected Thioglycosides at Room Temperature.
Authors: Brachet Etienne , Brion Jean‐Daniel , Alami Mouad , Messaoudi Samir 
Published: March 2014

AbstractA catalyst system based on in situ generated Ni(0) is shown to efficiently promote the coupling reaction of unprotected thiosaccharides with alkenyl, alkynyl, and aryl halides.
ChemInform Abstract: Divergent Total Syntheses of (‐)‐Lycopladine D, (+)‐Fawcetttidine, and (+)‐Lycoposerramine Q.
Authors: Zeng Chen , Zheng Changwu , Zhao Jingyun , Zhao Gang 
Published: March 2014

AbstractEnantioselective total syntheses of (+)‐fawcettidine (I) and (+)‐lycoposerramine Q (II) as well as the first total synthesis of (‐)‐lycopladine D (III) from a common intermediate is accomplished by a divergent path (not shown).
ChemInform Abstract: Formal Synthesis of (+)‐Tashiromine and Study Toward the Total Synthesis of (+)‐Stemoamide.
Authors: Chen Yue‐Jie , Bao Rui‐Yang , Zhang Xiao‐Dong , Tang Ye‐Feng 
Published: March 2014

AbstractTashiromine (IV) is obtained by employing an intramolecular asymmetric Mannich‐Type reaction as the key step.
ChemInform Abstract: Nivetetracyclates A and B: Novel Compounds Isolated from Streptomyces niveus.
Authors: Song Fuhang , et al. et al. 
Published: March 2014

AbstractA high‐throughput screening of a microbial natural product library leads to the discovery of two novel compounds named nivetetracyclates A (I) and B (II), which are produced by Streptomyces niveus designated as LS2151.
ChemInform Abstract: Artificial Carbonate Nanocrystals and Layered Structural Nanocomposites Inspired by Nacre: Synthesis, Fabrication and Applications
Authors: Yao Hong‐Bin , Ge Jin , Mao Li‐Bo , Yan You‐Xian , Yu Shu‐Hong 
Published: March 2014

AbstractReview: 199 refs.
ChemInform Abstract: Review on the Recent Progress in Low Band Gap Conjugated Polymers for Bulk Hetero‐Junction Polymer Solar Cells
Authors: Jhuo Hong‐Jyun , Yeh Po‐Nan , Liao Sih‐Hao , Li Yi‐Lun , Cheng Yu‐Shan , Chen Show‐An 
Published: March 2014

AbstractReview: 62 refs.
Neural organization of the second optic neuropil, the medulla, in the highly visual semiterrestrial crab Neohelice granulata
Authors: Sztarker Julieta , Tomsic Daniel 
Published: March 2014

ABSTRACTCrustaceans are widely distributed and inhabit very different niches. Many of them are highly visual animals. Nevertheless, the neural composition of crustacean optic neuropils deeper than the lamina is mostly unknown. In particular, semiterrestrial crabs possess a highly developed visual system and display conspicuous visually guided behaviors. A previous study shows that the first optic neuropil, the lamina of the crab Neohelice granulata, possesses a surprisingly high number of elements in each cartridge. Here, we present a comprehensive description of individual elements composing the medulla of that same species. Using Golgi impregnation, we characterized a wide variety of cells. Only considering the class of transmedullary neurons, we describe over 50 different morphologies including small‐ and large‐field units. Among others, we describe a type of centrifugal neuron hitherto not identified in other crustaceans or insects that probably feeds back information to every cartridge in the medulla. The possible functional role of such centrifugal elements is discussed in connection with the physiological and behavioral information on visual processing available for this crab. Taken together, the results reveal a very dense and complex neuropil in which several channels of information processing would be acting in parallel. We further examine our results considering the similarities and differences found between the layered organization and components of this crustacean medulla and the medullae of insects. J. Comp. Neurol. 522:3177–3193, 2014. © 2014 Wiley Periodicals, Inc.
Evidence that the central canal lining of the spinal cord contributes to oligodendrogenesis during postnatal development and adulthood in intact rats
Authors: Ševc Juraj , Matiašová Anna , Kútna Viera , Daxnerová Zuzana 
Published: March 2014

ABSTRACTTwo waves of oligodendrogenesis in the ventricular zone of the spinal cord (SC‐VZ) during rat development, which take place between embryonic days 14 and 18 (E14–E18) and E20–E21, have been described. In the VZ of the brain, unlike the SC‐VZ, a third wave of oligodendrogenesis occurs during the first weeks of postnatal development. Using immunofluorescence staining of intact rat SC tissue, we noticed the presence of small numbers of Olig2+/Sox‐10+ cells inside the lining of the central canal (CC) during postnatal development and adulthood. Olig2+/Sox‐10+ cells appeared inside the lining of the CC shortly after birth, and their number reached a maximum of approximately 0.65 ± 0.14 cell/40‐μm section during the second postnatal week. After the latter development, the number of Olig2+/Sox‐10+ cells decreased to 0.21 ± 0.07 (P36) and 0.18 ± 0.1 cell/section (P120). At P21, Olig2+/Sox‐10+ cells inside the CC lining started to express other oligodendroglial markers such as CNPase, RIP, and APC. Olig2+/Sox‐10+ cells usually did not proliferate inside the CC lining and were only rarely found to be immunoreactive against oligodendrocyte progenitor markers such as NG2 or PDGFRα. Using 5‐bromo‐2‐deoxyuridine administration at P2, P11, P22, or P120–P125, we revealed that these cells arose in the CC lining during postnatal development and adulthood. Our findings confirmed that the CC lining is the source of a small number of cells with an oligodendroglial phenotype during postnatal development and adulthood in the SC of intact rats. J. Comp. Neurol. 522:3194–3207, 2014. © 2014 Wiley Periodicals, Inc.
HUBzero and Pegasus: integrating scientific workflows into science gateways
Authors: McLennan Michael , Clark Steven , Deelman Ewa , Rynge Mats , Vahi Karan , McKenna Frank , Kearney Derrick , Song Carol 
Published: March 2014

SummaryIn this paper, we described the benefits and the challenges of integrating existing scientific workflow technologies into science gateways. Scientific workflow managers are powerful tools for handling large computational tasks. Domain scientists find it difficult to create new workflows, so many tasks that could benefit from workflow automation are often avoided or performed by hand. Two technologies have come together to bring the benefits of workflow to the masses. The Pegasus Workflow Management System can manage workflows comprised of millions of tasks, all the while recording data about the execution and intermediate results so that the provenance of the final result is clear. The HUBzero platform for scientific collaboration provides a venue for building and delivering tools to researchers and educators. With the press of a button, these tools can launch Pegasus workflows on national computing infrastructures and bring results back for plotting and visualization. As a result, the combination of Pegasus and HUBzero is bringing high‐throughput computing to a much wider audience. Copyright © 2014 John Wiley & Sons, Ltd.
A new flow cytometric method for differential cell counting in ascitic fluid
Authors: van de Geijn Gert‐Jan M. , van Gent Marc , van Pul‐Bom Natasja , Beunis Marlène H. , van Tilburg Antonie J. P. , Njo Tjin L. 
Published: March 2014

BackgroundCell counts in bodyfluids such as ascitic fluid can be difficult to perform and report rapidly. The current gold standard for cell counting in body fluids is a suitable automated cell counter or a manual counting chamber, combined with differential counting on a cytospin. This technique has several disadvantages, so we designed a new flow cytometric test for cell counting in ascites. We compared this with an automatic cell counter (LH750, Beckman Coulter) and manual counting of cytospins.MethodsAscitic samples (n = 53) from 38 patients were studied. Polymorphonuclear neutrophils (PMN), lymphocytes, eosinophils, and macrophages were defined by flow cytometry. We compared this with our reference method: the absolute cell concentration calculated from the leukocyte concentration of the LH750 combined with a differential cell count performed manually on a cytospin.ResultsThe outcomes of validation experiments (linearity, reproducibility, and detection limit) of the flow cytometric assay prove it is well suited for cell counting in ascitic fluid.ConclusionsBased on analytical performance, flow cytometry is suited for cell counting in ascitic fluid. An ascitic fluid cell count is frequently ordered to detect spontaneous bacterial peritonitis (SBP). If the PMN count is ≥250 cells/mm3, SBP is highly suspected. Using our reference method, we calculated the sensitivities and specificities to detect ≥250 PMN cells/mm3for the LH750 (100% and 65%, respectively) and flow cytometric assay (100%, 100%). As flow cytometry is easier and faster we recommend this method for rapid cell counting in ascitic fluid. © 2014 International Clinical Cytometry Society
Alterations of lipid profile are a risk factor for venous thromboembolism and thrombotic complications
Authors: García‐Raso Aránzazu , Ene Gabriela Simona , Sillero Pilar Llamas 
Published: March 2014

We studied a group of patients with thromboembolic disease, demographic data, thrombotic and classical cardiovascular risk factors, and thrombotic complications were collected. Lipid profile including total cholesterol, HDL cholesterol, LDL cholesterol, and triglycerides was established for all patients. Three hundred and thirty‐nine patients and 295 controls were included in the study. The mean age of both groups was 53.3 (±16.4) years for patients and 57.0 (±17.4) for controls (p = 0.006). Patient and control groups were composed of 53.4% (n = 181) and 52.2% (n = 154) of men, respectively (p = 0.765). LDL‐C > 180 mg/dL and TC > 220 mg/dL were associated with an increased risk of venous thromboembolism (VTE; OR: 7.76, 95% CI: 2.97–26.65, p < 0.0001 and OR: 2.22, 95%CI: 1.61–3.075, p < 0.0001, respectively). We found a statistically significant association between HDL‐C < 35 mg/dL (OR: 2.42, 95% CI: 1.15–5.16, p = 0.02) and LDL‐C > 180 mg/dL (OR: 1.93, 95% CI: 1.03–3.58, p = 0.04) with recurrent events. We found a significant association between HDL‐C < 35 mg/dL (OR: 2.35, 95%CI: 1.08–5.00, p = 0.031) and LDL‐C > 180 mg/dL (OR: 2.56, 95%CI: 1.34–4.83, p = 0.004) with PTS. Our study confirmed the association between dyslipidemia and VTE. In addition, alterations in the lipid profile were also related to a higher prevalence of thrombotic complications.Practical applications: A deeper understanding of the risk factors associated with VTE and its major complications, recurrence and post‐thrombotic syndrome, allow us to identify earlier and more effectively those individuals with an increased risk of thrombosis, and therefore apply appropriate therapeutic and prophylactic measures in certain thrombotic risk situations.
Oxytocin facilitates the sensation of social stress
Authors: Eckstein Monika , Scheele Dirk , Weber Kristina , Stoffel‐Wagner Birgit , Maier Wolfgang , Hurlemann René 
Published: March 2014

AbstractEssentially all social species experience social stress which can be a catalyst for detriments in mental and physical health. The neuropeptide oxytocin (OXT) has been shown to produce anxiolytic and antistress effects, thereby qualifying the OXT system as a promising drug target in the treatment of stress‐related disorders. However, recently it has been shown that OXT can have anxiogenic effects as well. In the present study, we used functional magnetic resonance imaging to scan the brains of 60 healthy men while they were exposed to social stress after they received either intranasal OXT (24 IU) or placebo treatment. Although OXT administration did not alter salivary cortisol levels as a surrogate marker of stress axis activity, our participants initially reported an increment in perceived social stress. This behavioral effect was paralleled on the neural level by increased activity in the precuneus and cingulate cortex. Taken together, our results support the hypothesis that OXT can induce a self‐referential processing bias which facilitates the sensation of social stress in the absence of altered endocrine responses. Hum Brain Mapp 35:4741–4750, 2014. © 2014 Wiley Periodicals, Inc.
Depicting the inner and outer nose: The representation of the nose and the nasal mucosa on the human primary somatosensory cortex (SI)
Authors: Gastl Mareike , Brünner Yvonne F. , Wiesmann Martin , Freiherr Jessica 
Published: March 2014

AbstractThe nose is important not only for breathing, filtering air, and perceiving olfactory stimuli. Although the face and hands have been mapped, the representation of the internal and external surface of the nose on the primary somatosensory cortex (SI) is still poorly understood. To fill this gap functional magnetic resonance imaging (fMRI) was used to localize the nose and the nasal mucosa in the Brodman areas (BAs) 3b, 1, and 2 of the human postcentral gyrus (PG). Tactile stimulation during fMRI was applied via a customized pneumatically driven device to six stimulation sites: the alar wing of the nose, the lateral nasal mucosa, and the hand (serving as a reference area) on the left and right side of the body. Individual representations could be discriminated for the left and right hand, for the left nasal mucosa and left alar wing of the nose in BA 3b and BA 1 by comparing mean activation maxima and Euclidean distances. Right‐sided nasal conditions and conditions in BA 2 could further be separated by different Euclidean distances. Regarding the alar wing of the nose, the results concurred with the classic sensory homunculus proposed by Penfield and colleagues. The nasal mucosa was not only determined an individual and bilateral representation, its position on the somatosensory cortex is also situated closer to the caudal end of the PG compared to that of the alar wing of the nose and the hand. As SI is commonly activated during the perception of odors, these findings underscore the importance of the knowledge of the representation of the nasal mucosa on the primary somatosensory cortex, especially for interpretation of results of functional imaging studies about the sense of smell.Hum Brain Mapp 35:4751–4766, 2014. ©2014 Wiley Periodicals, Inc.