bluuebunny/crossref_metadata_2025_split huggingface dataset:
Timeliness of investor reaction to corporate crypto‐asset investment: Evidence from types of disclosures
Authors: Hwang Hyoseok (David) , Zhang Jidong 
Published: July 2024

AbstractThis paper investigates investor reactions to corporate disclosures of crypto assets. We find that investor reactions are negative and insignificant in the 3‐day event window, while the reactions become positive afterward in the 5‐day event window. This suggests V‐shaped reverse reactions to the disclosures. We further investigate investor reactions to the different types and information quality of disclosures. The V‐shaped reverse‐reactions are statistically significant in 8‐K, 10‐Q, and 10‐K filings. In addition, investors are likely to react to Form 8‐K disclosures and disclosures with greater information quality. Our results have important implications for regulators and managerial practices regarding the disclosure of corporate investment decisions.
Collective consciousness and consumer behavior
Authors: White Katherine , Wang William , Aquino Karl 
Published: July 2024

AbstractWe build on the construct of collective consciousness, which reflects a view that a person can see the self as the subject that is attending, experiencing, or acting as a unitary collective agent, that is, from the perspective of “we” as opposed to “I.” Shteynberg (Journal of Consumer Psychology, 2024) proposes that collective consciousness can foster mutual trust and cooperation, thus having positive implications for both individuals and society. In this commentary, we discuss what the construct of collective consciousness might have to offer consumer researchers by considering when collective consciousness could be relevant in consumer contexts, its key psychological consequences, and how this theory could potentially build upon and interact with existing frameworks in consumer psychology. In addition, we consider some potential negative consequences of collective consciousness and point to potentially fruitful directions for future consumer research.
Navigating the integration of knowledge and research evidence in clinical practice for children's foot health: A multi‐professional survey
Authors: Hodgson Lisa , Price Carina , Reay Julie , Nester Chris , Morrison Stewart C. 
Published: July 2024

AbstractBackgroundAccess to clinical services for children with foot and ankle problems are important, but unravelling the complexity of practice and service delivery can be challenging. The pursuit and implementation of research evidence is critical for driving positive change in practice, but little is understood about the approaches to knowledge and research acquisition in children foot health.AimThe aim of the study was to: (1) explore multi‐professional habits of knowledge and research evidence acquisition in children's foot health; and (2) understand how clinicians integrate information for children and their families into their practice.MethodsThis was a descriptive, cross‐sectional online survey. Participants were included if they worked in the UK and had experience of working within paediatric services.ResultsThere were complete responses from 247 health professionals, representing physiotherapists (n = 160), podiatrists (n = 50), orthotists (n = 25), nurses and specialists in community public health nurses (health visitors) (n = 12). Three main themes were generated from the data: (1) Factors that influence knowledge and inform clinical practice. (2) The role of Professional Bodies in informing professional knowledge. (3) Health Professionals' views on managing health information for parents and caregivers.ConclusionsThis work advances understanding of the value health professionals' place in the development of materials for informing professional knowledge, as well as highlighting some of the challenges with translation of knowledge into clinical practice. The findings offer a national perspective of health professionals working on children's foot health and have highlighted that some of the most valued influences on clinical practice come from peer‐to‐peer networking.
Effects of Lactocaseibacillus paracasei subsp. paracasei NTU 101 on gut microbiota: a randomized, double‐blind, placebo‐controlled clinical study
Authors: Lin Tzu‐Hsing , Shih Tsung‐Wei , Lin Chih‐Hui 
Published: July 2024

AbstractBACKGROUNDLactocaseibacillus paracasei subsp. paracasei NTU 101 (NTU101) is a well‐known commercial probiotic with multiple health beneficial effects. In this study, the gut microbiota modulation effect of an NTU 101 product, Vigiis 101‐LAB, on healthy human was investigated in a randomized, double‐blind, placebo‐controlled human trial.RESULTSVigiis 101‐LAB significantly modulated human gut microbiota at fourth and sixth weeks of trial (anosim analysis, P = 0.001). It also significantly improved peristalsis (P = 0.003) and shortened defecation interval of subjects. The shift of gut microbiota is significantly fit with defecation interval (P = 0.009) and stool shape (P = 0.001) of subjects.CONCLUSIONOur results suggest that Vigiis 101‐LAB promotes human intestinal health with improvement of peristalsis and fecal quality. The gut modulation effects of Vigiis 101‐LAB subsequently raised the abundance of vitamin B7, vitamin K, pyrimidine and purine biosynthesis pathways. Vigiis 101‐LAB may promote peristalsis via purinergic pathway and possibly conferring prophylactic benefits against irritable bowel syndrome with constipation. © 2024 Society of Chemical Industry.
The posterior condyle grows in the direction of the increasing posterior condylar offset and the inclination angle of the ACL changes accordingly
Authors: Kamei Goki , Nekomoto Akinori , Nakata Kyohei , Tsuji Shunya , Hashiguchi Naofumi , Nakamae Atsuo , Ishikawa Masakazu , Adachi Nobuo 
Published: July 2024

AbstractPurposeThe purpose of this study was to reveal the changes in the shape of the posterior femoral condyle and the morphology of the ACL, both before and after epiphyseal closure. The hypothesis of this study is that the morphological change of the posterior femoral condyle and that of the ACL may be correlated to some extent.MethodsEighty‐one patients who underwent surgery for the knee joint (meniscal repair, arthroscopic synovectomy, medial patellofemoral ligament reconstruction) between 2016 and 2021 were included in this study, 48 patients aged 13 years or under (before epiphysis closure; mean age: 10.9 (range: 7–13) and 33 patients aged over 18 years or over (after epiphysis closure; mean age: 21.7 (range: 18–30). The shape of the posterior femoral condyle was evaluated via lateral view radiographs, and the morphology of the ACL was measured via sagittal and coronal magnetic resonance imaging (MRI) images.ResultsThe morphology of the posterior condyle in the lateral view radiograph in patients aged 13 and under was larger in the direction of the short axis of the femur compared with that in those aged 18 and over (p < 0.001). The mean value of the inclination angle of the anterior cruciate ligament (ACL) in the sagittal plane was significantly smaller in patients aged 13 and under (41.7° ± 3.7) than in those aged 18 and over (48.5° ± 4.2) (p < 0.001). The mean values of the inclination angle of the ACL in the coronal plane were significantly smaller in patients aged 13 and under (55.7° ± 6.4) than in those aged 18 and over (63.4° ± 4.4) (p < 0.001).ConclusionThis study evaluates and compares the shape of the posterior femoral condyle and the morphology of the ACL fiber before and after epiphyseal closure. The posterior femoral condyle grew posteriorly rather than longitudinally, and the inclination of the ACL fibers was thought to change accordingly.Level of EvidenceLevel Ⅲ.
External‐Cavity Free Plasmonic Nano‐Lasers Based on Quasi‐2D Perovskite Films
Authors: Dong Keqian , Lin Runkang , Huang Zhitao , Sun Jiaqian , Zhao Jing , Ma Jingteng , Lu Shudi , Li Mengyu , He Xintao , Liu Kong , Yue Shizhong , Wang Zhijie , Qu Shengchun 
Published: July 2024

AbstractPlasmonic nano‐lasers possess enormous potential for miniaturization of on‐chip integrated light sources. However, achieving plasmonic lasing requires high‐quality plasmonic resonant cavities, which are currently limited by complex, small‐scale, and costly production methods. Here, a new type of external‐cavity free plasmonic nano‐lasers is first presented with ultra‐thin thickness, achieved through the facile spin‐coating of quasi‐2D perovskite films onto monocrystalline silver sheets. The external‐cavity free plasmonic nano‐lasers exhibit obvious lasing behaviors, evidenced by a well‐defined threshold, significant linewidth narrowing, and distinct polarization dependence. The internal lasing mechanism relies on the scattering loop of surface plasmon polaritons (SPPs) by the disordered grains of the polycrystalline perovskite film. Based on this loop, SPPs experience feedback and amplification at the interface between silver sheets and perovskite films, leading to the lasing. Compared to photonic mode lasers, plasmonic nano‐lasers exhibit a significantly reduced feature size (< 80 nm), a dramatically faster lasing dynamic process (17 ps), and enhanced feedback stability and efficiency. The external‐cavity free plasmonic nano‐lasers eliminate the strict requirements for plasmonic resonant cavities to overcome traditional optical diffraction limits, making them highly significant for future applications in on‐chip photoelectric or all‐optical integration.
Brainstem dominant form of X‐linked adrenoleukodystrophy with a novel ABCD1 missense variant: A case report and literature review
Authors: Kang Yulai , Guo Lu , Min Zhuo , Zhang Lei , Zhang Lili , Tang Chunhua 
Published: July 2024

AbstractBackgroundX‐linked adrenoleukodystrophy (X‐ALD) is the most common peroxisomal disorder attributed to ABCD1 mutations. Case reports with predominant brainstem involvement are rare.Case PresentationIn this study, we reported a plateau male worker of X‐ALD characterized by progressive weakness accompanied by gait instability, mild nystagmus, and constipation. After 2 years of onset, a brain Magnetic Resonance Image (MRI) scan showed no abnormality but genetic analysis revealed a heterozygous mutation (c.1534G>A) in the ABCD1 gene. After 7 years of onset, although the patient was given aggressive dietary and symptomatic treatment in the course of the disease, a brain MRI scan showed predominantly brainstem damage, but serum concentrations of very long‐chain fatty acids were normal, and he had been bedridden for almost 2 years with severe bladder dysfunction, forcing him to undergo cystostomy. The patient was discharged with improved urinary retention and renal function.ConclusionsWe reported an X‐ALD patient with a novel ABCD1 variation characterized by brainstem damage and retrospectively summarized the clinical manifestation, MRI features, and genetic features of X‐ALD patients with brainstem damage.
Nursing postgraduates learning experience of professional curriculum in China: A qualitative study
Authors: Jiang Hongmei , Zhang Ting , Zhang Suofei , Ma Huijuan , Luo Yu 
Published: July 2024

AbstractAimThis study adopted the qualitative research method, aiming to explore the learning experience of nursing graduate professional curricula in China from the perspective of students and provided a basis for the continuous improvement of nursing graduate training.DesignA qualitative study.MethodsA purposive sampling method was employed to conduct semi‐structured in‐depth interviews with 14 nursing master's students enrolled in professional curricula from September 03, 2021, to December 8, 2022. The Colaizzi seven‐step analysis method was utilized for data analysis, summarization and extraction.ResultsFour themes emerged from the study findings: (i) The study of professional curricula is the cornerstone of scientific research work, but it is relatively boring; (ii) The teaching methods and assessment methods of postgraduate education need to be diversified; (iii) The postgraduate education needs to increase the study time of specialized courses and highlight the specialty characteristics; (iv) the study of professional curricula can enhance the comprehensive ability of postgraduate students.ConclusionThe study of professional curricula for post‐graduate nursing students plays an important role in the development of post‐graduate research and can statistically significant improve their comprehensive ability, but there are some problems such as boring courses, single teaching assessment methods and insufficient time. In the future teaching reform, it is necessary to highlight the specialty characteristics of nursing scientific research, optimize curriculum education and improve students' scientific research knowledge and thinking.Patient and Public ContributionsWe thank all participants for their valuable input throughout the study.
Entropy stable discontinuous Galerkin methods for the shallow water equations with subcell positivity preservation
Authors: Wu Xinhui , Trask Nathaniel , Chan Jesse 
Published: July 2024

AbstractHigh order schemes are known to be unstable in the presence of shock discontinuities or under‐resolved solution features, and have traditionally required additional filtering, limiting, or artificial viscosity to avoid solution blow up. Entropy stable schemes address this instability by ensuring that physically relevant solutions satisfy a semi‐discrete entropy inequality independently of discretization parameters. However, additional measures must be taken to ensure that solutions satisfy physical constraints such as positivity. In this work, we present a high order entropy stable discontinuous Galerkin (ESDG) method for the nonlinear shallow water equations (SWE) on two‐dimensional (2D) triangular meshes which preserves the positivity of the water heights. The scheme combines a low order positivity preserving method with a high order entropy stable method using convex limiting. This method is entropy stable and well‐balanced for fitted meshes with continuous bathymetry profiles.
Analyses of combined Merkel cell carcinomas with neuroblastic components suggests that loss of T antigen expression in Merkel cell carcinoma may result in cell cycle arrest and neuroblastic transdifferentiation
Authors: Kervarrec Thibault , Appenzeller Silke , Gramlich Susanne , Coyaud Etienne , Bachiri Kamel , Appay Romain , Macagno Nicolas , Tallet Anne , Bonenfant Christine , Lecorre Yannick , Kapfer Jean , Kettani Sami , Srinivas Nalini , Lei Kuan Cheok , Lange Anja , Becker Jürgen C , Sarosi Eva Maria , Sartelet Hervé , von Deimling Andreas , Touzé Antoine , Guyétant Serge , Samimi Mahtab , Schrama David , Houben Roland 
Published: July 2024

AbstractMerkel cell carcinoma (MCC) is an aggressive skin cancer frequently caused by genomic integration of the Merkel cell polyomavirus (MCPyV). MCPyV‐negative cases often present as combined MCCs, which represent a distinctive subset of tumors characterized by association of an MCC with a second tumor component, mostly squamous cell carcinoma. Up to now, only exceptional cases of combined MCC with neuroblastic differentiation have been reported. Herein we describe two additional combined MCCs with neuroblastic differentiation and provide comprehensive morphologic, immunohistochemical, transcriptomic, genetic and epigenetic characterization of these tumors, which both arose in elderly men and appeared as an isolated inguinal adenopathy. Microscopic examination revealed biphasic tumors combining a poorly differentiated high‐grade carcinoma with a poorly differentiated neuroblastic component lacking signs of proliferation. Immunohistochemical investigation revealed keratin 20 and MCPyV T antigen (TA) in the MCC parts, while neuroblastic differentiation was confirmed in the other component in both cases. A clonal relation of the two components can be deduced from 20 and 14 shared acquired point mutations detected by whole exome analysis in both combined tumors, respectively. Spatial transcriptomics demonstrated a lower expression of stem cell marker genes such as SOX2 and MCM2 in the neuroblastic component. Interestingly, although the neuroblastic part lacked TA expression, the same genomic MCPyV integration and the same large T‐truncating mutations were observed in both tumor parts. Given that neuronal transdifferentiation upon TA repression has been reported for MCC cell lines, the most likely scenario for the two combined MCC/neuroblastic tumors is that neuroblastic transdifferentiation resulted from loss of TA expression in a subset of MCC cells. Indeed, DNA methylation profiling suggests an MCC‐typical cellular origin for the combined MCC/neuroblastomas. © 2024 The Author(s). The Journal of Pathology published by John Wiley & Sons Ltd on behalf of The Pathological Society of Great Britain and Ireland.
Mechanical performance of epoxy matrix composites reinforced by physically and chemically treated hemp fiber
Authors: Sun Shuo , Yan Yongzhe , Zhou Chuyi , Pillay Selvum , Ning Haibin 
Published: July 2024

AbstractHemp fiber is one of the most common reinforcements for polymer matrix composites and it is widely used in various applications due to its environmentally friendliness, favorable physical and mechanical properties. In spite of the numerous merits of the hemp fiber reinforced polymer composites, improvement of poor interfacial properties between the hemp fiber and polymer matrix is limited. The main objective of this work is to investigate the effect of increased fiber surface area and alkaline surface treatment on the mechanical performance of hemp fiber reinforced epoxy composites. An elevated temperature aqueous debundling treatment was employed to generate a large number of individual fibers from fiber bundles and was associated with a threefold increase in specific fiber surface area. The fiber dimension and surface properties were investigated through optical microscopy, confocal microscopy, and scanning electron microscopy. The effects of different debundling treatment times and additional alkaline treatment on the mechanical properties were studied. It was found that composites reinforced by the debundled hemp fiber with further alkaline treatment exhibited the best tensile and flexural properties in comparison to other composites reinforced with debundled hemp fiber without further alkaline treatment or with untreated hemp fiber.Highlights
Provided a new physical method for separating hemp fiber bundle into individual hemp fibers using boiling water and blending.
Debundled fibers resulted in a 3.5 times increase in fiber surface area for better bonding with epoxy matrix.
Debundling process combined with chemical (alkaline) treatment to further improve the compatibility between individual fiber and epoxy.
The effects of the debundling only, alkaline treatment only, and combined debundling + alkaline treatment on composite properties were studied.
Interfacial layer properties and enthalpy relaxation of polymer nanocomposites: Effect of nanoparticle dispersion
Authors: Lv Zhijian , Xiao Ran , Fang Yini , Zhu Zeyu , Lin Yu 
Published: July 2024

AbstractInvestigating the effect of nanoparticle dispersion morphology on the properties of the interfacial layer of polymer nanocomposites (PNCs) provides an important theoretical basis for designing and regulating the macroscopic properties of PNCs. Differential scanning calorimetry (DSC) and broadband dielectric spectroscopy (BDS) were used to investigate the characteristic parameters of the interfacial area, segmental dynamics and enthalpy relaxation of PNCs with nanoparticle agglomerates and uniformly dispersed morphology. The volume fraction of the interfacial area (φint) and the extent of influence of the interfacial area on the enthalpy hysteresis reduction (χint) in PNCs with agglomerated nanoparticles are lower than that of PNCs with uniformly dispersed nanoparticles for the same nanoparticle loading. Because of the irregular structure of the nanoparticle aggregate morphology, the linear relationships between φint and nanoparticle content is not valid in PNCs with agglomerated nanoparticles. Interestingly, φint obtained by BDS and χint have a clearly linear relationship in all PNCs, independent of nanoparticle dispersion morphology. Such universal quantitative relationship provides a new research methodology for investigating the characteristic parameters of the interfacial area in PNCs, and facilitates the construction of a correspondence between the microscopic parameters of interfacial area and the macroscopic properties of PNCs.Highlights
The linear relationships between φint and nanoparticle content are not valid in PNCs with agglomerated nanoparticles.
The linear relationships between φint and the decreased degree of ΔHR can be noted in all PNCs, independent of nanoparticle dispersion morphology.
The universal correspondence provides a new research methodology for investigating the characteristic parameters of the interface layer in PNCs.
Naringenin inhibits the microsomal triglyceridetransfer protein/apolipoprotein B axis to inhibit intestinal metaplasia progression
Authors: Huang Xiangming , Zhang Mengqiu , Gu Lina , Zhou Ziyan , Shi Shengtong , Fan Xinyu , Tong Wei , Liu Dazhi , Fang Jihu , Huang Xinen , Fang Zhijun , Lu Min 
Published: July 2024

AbstractIntestinal metaplasia (IM) is a premalignant condition that increases the risk for subsequent gastric cancer (GC). Traditional Chinese medicine generally plays a role in the treatment of IM, and the phytochemical naringenin used in Chinese herbal medicine has shown therapeutic potential for the treatment of gastric diseases. However, naringenin's specific effect on IM is not yet clearly understood. Therefore, this study identified potential gene targets for the treatment of IM through bioinformatics analysis and experiment validation. Two genes (MTTP and APOB) were selected as potential targets after a comparison of RNA‐seq results of clinical samples, the GEO dataset (GSE78523), and naringenin‐related genes from the GeneCards database. The results of both cell and animal experiments suggested that naringenin can improve the changes in the intestinal epithelial metaplasia model via MTTP/APOB expression. In summary, naringenin likely inhibits the MTTP/APOB axis and therefore inhibits IM progression. These results support the development of naringenin as an anti‐IM agent and may contribute to the discovery of novel IM therapeutic targets.