bluuebunny/crossref_metadata_2025_split huggingface dataset:
Penser la crise ou plaidoyer pour une réflexion critique sur la crise de la crise à partir de l'œuvre de Hannah Arendt
Authors: Ehrwein Nihan Céline 
Published: October 2013

Le concept de « crise » n’a rien d’évident. Dans cet article, l’auteure se propose d’explorer quelques-uns de ses possibles sens, d’en mesurer la pertinence et l’actualité. Elle se tourne pour ce faire vers la philosophe Hannah Arendt, dont la pensée peut, selon elle, être définie comme une « pensée de la crise ». L’exploration de la conception arendtienne du politique et de « la vie de l’esprit » conduit alors l’auteure à souligner la dimension foncièrement critique de la réalité humaine. Notre existence, nous dit-elle, se déploie sur fond d’une crise/de crises qui tout à la fois fondent et menacent en permanence notre humanité. Partant, l’auteure nous invite à distinguer entre deux acceptions du concept de « crise ». Elle relève que celui-ci peut être employé pour désigner aussi bien une situation d’instabilité , potentiellement créatrice et salutaire, qu’une situation destructrice de déstabilisation . L’auteure conclut en proposant d’appliquer cette distinction aux développements en cours dans le domaine de l’« intelligence ambiante ».
La crise financière, l'avenir du travail et leurs conséquences pour les assurances sociales
Authors: Flückiger Yves 
Published: October 2013

Au cours des dernières décennies, le marché du travail a subi d’importantes mutations. Ces changements se sont produits de surcroît dans le cadre de sociétés vieillissantes et dans une économie globalisée. À ces défis structurels sont venus s’ajouter, plus récemment, les effets de la crise financière. Elle a provoqué, dans de nombreux pays, une baisse du PIB qui a entraîné une augmentation du chômage particulièrement brutale pour certains groupes de la population, tels que les jeunes en fin de formation, et dans plusieurs pays du sud de l’Europe qui enregistrent, aujourd’hui, des taux de chômage supérieurs à 20 % de la population active. Cet article a pour objectif d’examiner, en premier lieu, les défis auxquels se trouvent confrontés les systèmes de sécurité sociale en Europe et dans le monde. Sur base de ces constats, sont mises en évidence les réponses concrètes qui peuvent être apportées pour répondre à ces défis en présentant quelques solutions de politique économique susceptibles d’être adoptées.
Crise de la métaphysique, vérité et relativisme
Authors: Riaudel Olivier 
Published: October 2013

Quelques textes pontificaux récents développent la thèse d’une corrélation entre une crise de la métaphysique et une crise de la vérité, un développement du relativisme. Après avoir montré qu’en réalité cette expression « crise de la métaphysique » est polysémique, l’article se centre sur l’identification présupposée entre « rationnel » et « universel ». Développant l’idée que la rationalité d’un discours, toujours marquée par des décisions libres, se vérifie plus par la possibilité d’une universalisation que par une universalité « pure », l’auteur voit dans ce diagnostic d’une « crise de la métaphysique » le résultat d’une façon – certes métaphysique, mais non point universelle – de poser la question de l’universel et de la vérité.
Crise, construction identitaire et vocation
Authors: Fournier Claude-Alexandre 
Published: October 2013

Le rôle de la crise dans des parcours de vie a marqué les premières études en psychologie de la religion. Une solution religieuse à des difficultés psychiques a très tôt été envisagée par les psychologues. Dans les termes de William James, la réponse religieuse à la crise, vue comme une division du self , vise un retour à l’unité. Dans cet article, nous envisagerons un type de crise particulier : l’emprise maternelle vécue dans l’enfance. Nous verrons en quoi elle marque un parcours de vie qui mène au choix de la vie monastique. Dans le lien si particulier que l’emprise entretient avec le langage et la narrativité, nous verrons comment Dieu peut venir au secours d’une narrativité confisquée pour que l’individu puisse prendre en charge son histoire, son identité.
Crise et vie spirituelle
Authors: Manicardi Luciano 
Published: October 2013

Après avoir examiné la dimension spirituelle de la « crise », en cherchant surtout ce qui correspond à cette notion dans l’Écriture, on passe en revue certains facteurs qui caractérisent la crise de la vie spirituelle chrétienne en Occident. La contribution se termine en formulant quelques lignes prospectives pour vivre la foi en ce temps : valoriser la tradition biblique sapientiale, redécouvrir l’humanité de la foi, s’inspirer de la pratique d’humanité de Jésus de Nazareth telle qu’en témoignent les évangiles.
La crise, ou comment ne pas en sortir...
Authors: Lemoine Laurent 
Published: October 2013

Sortir de la crise serait-il une fausse bonne idée ? Surtout lorsqu’il s’agit de la crise psychique du sujet contemporain sous les aspects multiformes qu’elle peut revêtir, du burn out des métiers stressés d’aujourd’hui au petit personnage de Scratch du dernier épisode de L’Âge de glace , sorte de mascotte d’un désir congelé et obturé par la quête sans fin de l’objet- toy de la psycho-sexualité actuelle. Il s’agit plutôt d’apprendre à faire quelque chose de la crise, pour remettre en mouvement les continents de la psyché personnelle ou collective figés dans les glaces... À cet égard, les gender studies fustigées en raison de nombreux excès offrent pourtant des possibilités trop peu explorées du côté de ce qui serait comme la via negationis d’une conception de l’homme, non pas d’abord maître en sa maison, mais peut-être plus encore soumis à des mouvements contradictoires ou paradoxaux de sa structuration personnelle et de la posture éthique qu’il peut en extraire. Selon cet axe de pensée, la différence des sexes est toujours-encore-à-advenir.
Krisis : jugement et promesse
Authors: Causse Jean-Daniel 
Published: October 2013

En conclusion du dossier, Jean-Daniel Causse aborde trois aspects principaux de la crise : D’abord, la crise – référée à l’étymologie – est un appel à distinguer, parce que le temps où ce que nous avions établi vacille. La crise ouvre une question : et si nous avions confondu, sans le savoir, ce qui fait vivre avec ce qui produit de la mort ? Ensuite, la crise suppose de reprendre théologiquement le jugement sans laquelle aucune promesse n’est possible. Le jugement n’est pas discours, mais mise en question. Il arrête la linéarité d’une course et oblige à inventer un chemin. Ricœur avait noté que la crise de notre temps se caractérise par une absence de consensus et de conviction. La conviction comme capacité de créer du lien est un enjeu majeur de la promesse qui est le troisième élément relevé.
Novel Regulatory Action of Ribosomal Inactivation on Epithelial Nod2-Linked Proinflammatory Signals in Two Convergent ATF3-Associated Pathways
Authors: Park Seong-Hwan , Do Kee Hun , Choi Hye Jin , Kim Juil , Kim Ki-Hyung , Park Jiyeon , Oh Chang Gyu , Moon Yuseok 
Published: October 2013

Abstract
In response to excessive nucleotide-binding oligomerization domain–containing protein 2 (Nod2) stimulation caused by mucosal bacterial components, gut epithelia need to activate regulatory machinery to maintain epithelial homeostasis. Activating transcription factor 3 (ATF3) is a representative regulator in the negative feedback loop that modulates TLR-associated inflammatory responses. In the current study, the regulatory effects of ribosomal stress-induced ATF3 on Nod2-stimulated proinflammatory signals were assessed. Ribosomal inactivation caused persistent ATF3 expression that in turn suppressed proinflammatory chemokine production facilitated by Nod2. Decreased chemokine production was due to attenuation of Nod2-activated NF-κB and early growth response protein 1 (EGR-1) signals by ATF3. However, the underlying molecular mechanisms involve two convergent regulatory pathways. Although ATF3 induced by ribosomal inactivation regulated Nod2-induced EGR-1 expression epigenetically through the recruitment of histone deacetylase 1, NF-κB regulation was associated with posttranscriptional regulation by ATF3 rather than epigenetic modification. ATF3 induced by ribosomal inactivation led to the destabilization of p65 mRNA caused by nuclear entrapment of transcript-stabilizing human Ag R protein via direct interaction with ATF3. These findings demonstrate that ribosomal stress-induced ATF3 is a critical regulator in the convergent pathways between EGR-1 and NF-κB, which contributes to the suppression of Nod2-activated proinflammatory gene expression.
Reduced Effectiveness of CD4+Foxp3+ Regulatory T Cells in CD28-Deficient NOD.H-2h4 Mice Leads to Increased Severity of Spontaneous Autoimmune Thyroiditis
Authors: Ellis Jason S. , Hong So-Hee , Zaghouani Habib , Braley-Mullen Helen 
Published: October 2013

Abstract
NOD.H-2h4 mice given NaI in their drinking water develop iodine-accelerated spontaneous autoimmune thyroiditis (ISAT) with chronic inflammation of the thyroid by T and B cells and production of anti-mouse thyroglobulin (MTg) autoantibody. CD28−/− NOD.H-2h4 mice, which have reduced numbers of CD4+Foxp3+ regulatory T cells (Tregs), were developed to examine the role of Tregs in ISAT development. CD28−/− NOD.H2-h4 mice develop more severe ISAT than do wild-type (WT) mice, with collagen deposition (fibrosis) and low serum T4. CD28−/− mice have increased expression of proinflammatory cytokines IFN-γ and IL-6, consistent with increased mononuclear cell infiltration and tissue destruction in thyroids. Importantly, transferring purified CD4+Foxp3+ Tregs from WT mice reduces ISAT severity in CD28−/− mice without increasing the total number of Tregs, suggesting that endogenous Tregs in CD28−/− mice are functionally ineffective. Endogenous CD28−/− Tregs have reduced surface expression of CD27, TNFR2 p75, and glucocorticoid-induced TNFR-related protein compared with transferred CD28+/+ Tregs. Although anti-MTg autoantibody levels generally correlate with ISAT severity scores in WT mice, CD28−/− mice have lower anti-MTg autoantibody responses than do WT mice. The percentages of follicular B cells are decreased and those of marginal zone B cells are increased in spleens of CD28−/− mice, and they have fewer thyroid-infiltrating B cells than do WT mice. This suggests that CD28 deficiency has direct and indirect effects on the B cell compartment. B cell–deficient (B−/−) NOD.H-2h4 mice are resistant to ISAT, but CD28−/−B−/− mice develop ISAT comparable to WT mice and have reduced numbers of Tregs compared with WT B−/− mice.
Current Pharmacological and Nonpharmacological Options for the Management of Insomnia
Authors: Pigeon Wilfred R. , Bishop Todd M. , Marcus Jonathan A. 
Published: October 2013

Insomnia continues to be a major public health concern and to have a pronounced and detrimental effect on health care costs, productivity, and quality of life. Efficacious pharmacological and nonpharmacological interventions have emerged over the past few decades, giving providers several options for addressing this disruptive condition; these are herein reviewed. Benzodiazepines have long been the pharmacological treatment of choice for insomnia; however, novel hypnotics being developed by the pharmaceutical industry show promise in addressing insomnia with fewer side effects. From the nonpharmacological perspective, several different single-component interventions such as stimulus control have been shown to be effective, although a combination of these approaches (eg, cognitive-behavioral therapy for insomnia) also enjoy strong empirical support. Future research should continue to examine how sequencing of treatment components, treating different patient cohorts, and combinations of pharmacological and non-pharmacological treatments influence patient outcome.
Thiazole‐Based Novel Terpolymer Ligand and Its Transition Metal Complexes: Thermal and Biological Studies
Authors: Ahamed Mohamed A. Riswan , Burkanudeen Abdul R. 
Published: October 2013

ABSTRACTA new terpolymer ligand involving 2‐amino‐6‐nitro‐ benzothiazole, melamine, and formaldehyde (BMF) has been synthesized in the presence of dimethyl formamide medium. The BMF ligand was characterized by elemental analysis and various spectral techniques like Fourier transform infrared (FTIR) spectroscopy, ultraviolet (UV)–visible spectroscopy, and 1H & 13C nuclear magnetic resonance (NMR) spectroscopy to elucidate the structure and properties of the terpolymer ligand. The BMF metal complexes were prepared using the BMF ligand with some transition metal ions, such as Cu2+, Ni2+, and Zn2+ ions, in the presence of ethanol medium. The prepared complexes have been characterized by elemental analysis and FTIR, electronic, electron spin resonance, and 1H & 13C NMR spectral studies. The molecular weight of the BMF ligand and its metal complexes was determined by gel permeation chromatography. The surface features and crystalline behavior of the ligand and its complexes were analyzed by scanning electron microscope (SEM) and X‐ray diffraction (XRD) methods. Thermal stability of the ligand and its metal complexes was studied by thermogravimetric analysis (TGA). Kinetic parameters such as activation energyand order of reaction (n), and thermodynamic parameters namely entropy change, free energy change, apparent entropy, and frequency factor were calculated using Freeman–Carroll, Sharp–Wentworth, and Phadnis–Deshpande (PD) methods. Thermal degradation model of the terpolymer ligand and its metal complexes was also proposed using the PD method. The antibacterial activities of the BMF ligand and its metal complexes were checked against chosen microbes such as Shigella sonnei, Escherichia coli, Klebsiella species, Staphylococcus aureus, Bacillus subtilis, and Salmonella typhimurium. © 2013 Wiley Periodicals, Inc. Adv Polym Technol 2013, 32, 21376; View this article online at wileyonlinelibrary.com. DOI 10.1002/adv.21376
Malformations among the X‐linked intellectual disability syndromes
Authors: Stevenson Roger E. , Schwartz Charles E. , Rogers R. Curtis 
Published: October 2013

AbstractMalformations are significant contributions to childhood mortality and disability. Their co‐occurrence with intellectual disability may compound the health burden, requiring additional evaluation and management measures. Overall, malformations of greater or lesser severity occur in at least some cases of almost half of the 153 XLID syndromes. Genitourinary abnormalities are most common, but tend to contribute little or no health burden and occur in only a minority of cases of a given XLID syndrome. Some malformations (e.g., lissencephaly, hydranencephaly, long bone deficiency, renal agenesis/dysplasia) are not amenable to medical or surgical intervention; others (e.g., hydrocephaly, facial clefting, cardiac malformations, hypospadias) may be substantially corrected. © 2013 Wiley Periodicals, Inc.
Solid state grafting copolymerization of acrylamide onto poly(vinyl alcohol) initiated by redox system
Authors: Lu Yan , Jing Rong , Kong Qin‐ming , Zhu Pu‐xin 
Published: October 2013

ABSTRACTA solid state grafting copolymerization of acrylamide (AM) onto poly(vinyl alcohol) (PVA) was conducted with ammonium persulfate and sodium bisulfite redox system as initiators. Before the reaction the PVA powder and required amount of AM were mixed evenly, and sprayed with water to swell the PVA powder and to dissolve AM. Then the swollen PVA powder was sprayed with the redox solution, and the reaction temperature was controlled at a temperature between 30°C and 80°C for 120 min. The grafting percentage and efficiency were determined as functions of monomer/PVA ratio, initiator concentration and reaction temperature. The structure and performance of the graft copolymers were confirmed by FTIR‐ATR, XRD, 13C NMR, and thermogravimetric analysis, together with mechanical property and apparent viscosity measurements. It has been confirmed that grafting copolymerization of AM onto PVA initiated by this redox system occurred with higher grafting percentage and efficiency in the solid state. The thermal stability and water‐solubility of grafted PVA were found to be better than those of unmodified PVA. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2014, 131, 39938.
Status and the potential for extinction of the largetooth sawfish Pristis pristis in the Atlantic Ocean
Authors: Fernandez‐Carvalho Joana , Imhoff Johanna L. , Faria Vicente V. , Carlson John K. , Burgess George H. 
Published: October 2013

ABSTRACT

Sawfishes currently are among the most threatened elasmobranchs in the world. Only two species inhabit Atlantic waters: the largetooth sawfish (Pristis pristis) and the smalltooth sawfish (Pristis pectinata), both having suffered dramatic declines in their ranges.
The goal of this study was to evaluate the status of P. pristis in the Atlantic, and estimate local extinction risk based on historical and recent occurrence records. In order to accomplish these goals, a thorough search for historical and recent records of P. pristis in the Atlantic was conducted, by reviewing scientific and popular literature, museum specimens, and contacting regional scientists from the species’ historical range.
In total, 801 P. pristis records (1830–2009) document its occurrence in four major regions in the Atlantic: USA (n = 41), Mexico and Central America (n = 535), South America (n = 162), and West Africa (n = 48). Locality data were not available for 15 records.
Historical abundance centres were the Colorado‐San Juan River system in Nicaragua and Costa Rica (and secondarily Lake Izabal of Guatemala), the Amazon estuary, and coastal Guinea‐Bissau.
Currently, the species faces drastic depletion throughout its entire former range and centres of abundance. It appears to have been extirpated from several areas. The probability of extinction was highest in the USA, northern South America (Colombia to Guyane), and southern West Africa (Cameroon to Namibia).
Currently, the Amazon estuary appears to have the highest remaining abundance of P. pristis in the Atlantic, followed by the Colorado–San Juan River system in Nicaragua and Costa Rica and the Bissagos Archipelago in Guinea Bissau. Therefore the protection of these populations is crucial for the preservation and recovery of the species. Copyright © 2013 John Wiley & Sons, Ltd.
Novel Rheumatoid Arthritis Susceptibility Locus at 22q12 Identified in an Extended UK Genome‐Wide Association Study
Authors: Orozco Gisela , Viatte Sebastien , Bowes John , Martin Paul , Wilson Anthony G. , Morgan Ann W. , Steer Sophia , Wordsworth Paul , Hocking Lynne J. ,   UK Rheumatoid Arthritis Genetics Consortium,   Wellcome Trust Case Control Consortium,   Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate Consortium, Barton Anne , Worthington Jane , Eyre Stephen 
Published: October 2013

ObjectiveThe number of confirmed rheumatoid arthritis (RA) loci currently stands at 32, but many lines of evidence indicate that expansion of existing genome‐wide association studies (GWAS) enhances the power to detect additional loci. This study was undertaken to extend our previous RA GWAS in a UK cohort, adding more independent RA cases and healthy controls, with the aim of detecting novel association signals for susceptibility to RA in a homogeneous UK cohort.MethodsA total of 3,223 UK RA cases and 5,272 UK controls were available for association analyses, with the extension adding 1,361 cases and 2,334 controls to the original GWAS data set. The genotype data for all RA cases were imputed using the Impute program version 2. After stringent quality control thresholds were applied, 3,034 cases and 5,271 controls (1,831,729 single‐nucleotide polymorphisms [SNPs]) were available for analysis. Association testing was performed using Plink software.ResultsThe analyses indicated a suggestive association with susceptibility to RA (P < 0.0001) for 6 novel RA loci that have been previously found to be associated with other autoimmune diseases; these 6 SNPs were genotyped in independent samples. Two of the associated loci were validated, one of which was associated with RA at genome‐wide levels of significance in the combined analysis, identifying a novel RA locus at 22q12 (P = 6.9 × 10−9). In addition, most of the previously known RA susceptibility loci were confirmed to be associated with RA, and for 16 of the loci, the strength of the association was increased.ConclusionThis study identified a new RA locus mapping to 22q12. These results support the notion that increasing the power of GWAS enhances novel gene discovery.
A study of the influence of severe environmental conditions on common traffic congestion features
Authors: Rehborn Hubert , Koller Micha 
Published: October 2013

SUMMARYOn the basis of real traffic and environmental data measured on German freeways, we studied common features of traffic congestion under the influence of severe weather conditions. We have found that traffic features [J] and [S] defining traffic phases “wide moving jam” (J) and “synchronized flow” (S) in Kerner's three‐phase theory are indeed common spatiotemporal traffic features. The quantitative parameters for both traffic phases [S] and [J] were investigated in a comparison of “ideal” weather conditions (good visibility and no precipitation) and severe weather situations (icy road, wind, precipitation, etc.). We showed spatiotemporal congested patterns in several space–time diagrams based on the Automatic Tracking of Moving Jams/Forecasting of Traffic Objects (ASDA/FOTO) model reconstruction for roadside detectors. A statistical study of traffic phase [J] parameters was presented, showing the average values and standard deviation of the quantities. Similarities and differences were analyzed, and some consequences for vehicular applications were discussed to cope with severe weather conditions. Copyright © 2013 John Wiley & Sons, Ltd.
Implantable and ingestible medical devices with wireless telemetry functionalities: A review of current status and challenges
Authors: Kiourti Asimina , Psathas Konstantinos A. , Nikita Konstantina S. 
Published: October 2013

AbstractWireless medical telemetry permits the measurement of physiological signals at a distance through wireless technologies. One of the latest applications is in the field of implantable and ingestible medical devices (IIMDs) with integrated antennas for wireless radiofrequency (RF) communication (telemetry) with exterior monitoring/control equipment. Implantable medical devices (MDs) perform an expanding variety of diagnostic and therapeutic functions, while ingestible MDs receive significant attention in gastrointestinal endoscopy. Design of such wireless IIMD telemetry systems is highly intriguing and deals with issues related to: operation frequency selection, electronics and powering, antenna design and performance, and modeling of the wireless channel. In this paper, we attempt to comparatively review the current status and challenges of IIMDs with wireless telemetry functionalities. Full solutions of commercial IIMDs are also recorded. The objective is to provide a comprehensive reference for scientists and developers in the field, while indicating directions for future research. Bioelectromagnetics. 35:1–15, 2014. © 2013 Wiley Periodicals, Inc.