bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: A Catalyst‐Free Reaction in Water: Synthesis of Benzo[4,5]imidazo[1,2‐a]pyrimido[4,5‐d]pyrimidin‐4(1H)‐one Derivatives.
Authors: Liu Junhua , Lei Min , Hu Lihong 
Published: January 2013

AbstractThe three‐component condensation of aminobenzimidazole (I), aromatic aldehydes (II), and cyanoacetamide (III) provides a series of title derivatives like (IV) in high yields.
ChemInform Abstract: Synthesis of Fused N‐Heterocycles via Tandem C—H Activation.
Authors: Meng Ge , Niu Hong‐Ying , Qu Gui‐Rong , Fossey John S. , Li Jian‐Ping , Guo Hai‐Ming 
Published: January 2013

AbstractThe synthesis of fused N‐heterocycles is developed using an intramolecular cyclization of purines or benzimidazoles.
ChemInform Abstract: Rapid Access to Multisubstituted Pyrimido[4,5‐b][1,4]diazepine‐2,4,6‐trione and Pyrimido[4,5‐b][1,4]diazepine‐2,4‐dione as Novel and Versatile Scaffolds for Drug Discovery.
Authors: Li Gong , Wang Xiaowei , Tian Chao , Zhang Tongbo , Zhang Zhili , Liu Junyi 
Published: January 2013

AbstractThe synthetic strategy for the preparation of the title compounds involves a reductive cyclization of substrates (III) to give intermediates (IV), followed by sequential N‐functionalization and deprotection as is demonstrated for example (VIa).
ChemInform Abstract: Platinum Catalyzed 7‐endo Cyclization of Internal Alkynyl Amides and Its Application to Synthesis of the Caprazamycin Core.
Authors: Tsukano Chihiro , Yokouchi Shinsuke , Girard Anne‐Lise , Kuribayashi Toshifumi , Sakamoto Shota , Enomoto Taro , Takemoto Yoshiji 
Published: January 2013

AbstractThe Pt‐catalyzed cyclization of various internal alkynylamides provides access towards diazepines with excellent 7‐endo selectivity.
ChemInform Abstract: A Synthon for a 14‐Electron Ir(III) Species: Catalyst for Highly Selective β‐(Z) Hydrosilylation of Terminal Alkynes.
Authors: Iglesias Manuel , Perez‐Nicolas Maria , Sanz Miguel Pablo J. , Polo Victor , Fernandez‐Alvarez Francisco J. , Perez‐Torrente Jesus J. , Oro Luis A. 
Published: January 2013

AbstractThe reaction also works with diphenylmethylsilane and dimethylphenylsilane, respectively.
ChemInform Abstract: A Mild Method for Indium(III)‐Catalyzed 1,4‐Hydrosilylation of α,β‐Enone Esters with Triethylsilane and Trifluoroacetic Acid.
Authors: Xing Ping , Zang Wei , Huang Zuo‐gang , Zhan Yue‐xiong , Zhu Chuan‐jun , Jiang Biao 
Published: January 2013

Abstractα‐Keto esters of type (I) undergo an efficient stereoselective hydrosilylation give moderate yields of the desired α,β‐unsaturated esters (III).
ChemInform Abstract: Enantioselective Organocatalytic Thiol Addition to α,β‐Unsaturated α‐Amino Acid Derivatives.
Authors: Breman Arjen C. , Smits Jan M. M. , de Gelder Rene , van Maarseveen Jan H. , Ingemann Steen , Hiemstra Henk 
Published: January 2013

AbstractThe title substrates (I) are prepared and applied in cinchona‐catalyzed asymmetric sulfa‐Michael additions.
ChemInform Abstract: Synthesis and Biological Evaluation of Unprecedented Ring‐Expanded Nucleosides (RENs) Containing the Imidazo[4,5‐d][1,2,6]oxaidazepine Ring System.
Authors: D'Errico Stefano , Oliviero Giorgia , Amato Jussara , Borbone Nicola , Cerullo Vincenzo , Hemminki Akseli , Piccialli Vincenzo , Zaccaria Sabrina , Mayol Luciano , Piccialli Gennaro 
Published: January 2013

AbstractDerivatives (IV) inhibit the cell growth of breast cancer derived MCF‐7 cells.
ChemInform Abstract: C—C Cross‐Coupling Reactions of O6‐Alkyl‐2‐haloinosine Derivatives and a One‐Pot Cross‐Coupling/O6‐Deprotection Procedure.
Authors: Gurram Venkateshwarlu , Pottabathini Narender , Garlapati Ramesh , Chaudhary Avinash B. , Patro Balaram , Lakshman Mahesh K. 
Published: January 2013

AbstractC‐2 Bromo‐ and chloropurine nucleosides (I) are shown to have comparable reactivity in the C—C crosscoupling reaction with aryl or alkylboronic acids; however, cleavage of the O6‐methyl protecting group is known to be problematic.
ChemInform Abstract: Ultralong Monoclinic ZnV2O6 Nanowires: Their Shape‐Controlled Synthesis, New Growth Mechanism, and Highly Reversible Lithium Storage in Lithium‐Ion Batteries.
Authors: Sun Yan , Li Chunsheng , Wang Lina , Wang Yaozu , Ma Xuegang , Ma Peijian , Song Mingyang 
Published: January 2013

AbstractThe title nanowires with diameters of about 70—120 nm and lengths of about 80—100 μm are hydrothermally synthesized from aqueous mixtures of Zn(NO3)2 and NH4VO3 (autoclave, 100—200 °C, 3—168 h).
ChemInform Abstract: Preparation of Photocatalytic Au—Ag2Te Nanomaterials.
Authors: Lin Zong‐Hong , Shih Zih‐Yu , Roy Prathik , Chang Huan‐Tsung 
Published: January 2013

AbstractTe nanowires, nanopencils, and nanorice materials are prepared by reduction of TeO2 with various concentrations of N2H4 (16, 8, and 4 M, resp.) at 25 °C (nanowires) and 60 °C.
ChemInform Abstract: Enzymatic Glycosylation of Small Molecules: Challenging Substrates Require Tailored Catalysts
Authors: Desmet Tom , Soetaert Wim , Bojarova Pavla , Kren Vladimir , Dijkhuizen Lubbert , Eastwick‐Field Vanessa , Schiller Alexander 
Published: January 2013

AbstractReview: 215 refs.
Compression Behavior of Moist Spherical Zeolite 4A Granules
Authors: Müller Peter , Tomas Jürgen 
Published: January 2013

AbstractDas Materialverhalten von drei Partikelgrößen elastisch‐plastischer Zeolith 4A‐Granulate wurde experimentell mittels Druckbeanspruchung untersucht. Die dabei aufgezeichneten Kraft‐Weg‐Kurven wurden mithilfe mechanischer Modelle aus der Literatur angepasst. Bestimmt wurde zudem der Einfluss der Partikelgröße und der Feuchtebeladung auf das Materialverhalten. Ermittelt wurden ebenfalls die spezifischen Bruchenergieverteilungen und die energetisch äquivalenten Bruchgeschwindigkeitsverteilungen. Die äquivalente Bruchgeschwindigkeit entspricht bei Prallbeanspruchung der Aufprallgeschwindigkeit der Granulate auf eine steife Wand, bei der Bruch eintreten würde.
Surface‐Tension‐Confined Microfluidics and Their Applications
Authors: You Inseong , Yun Nayeon , Lee Haeshin 
Published: January 2013

AbstractThis article is a brief overview of the emerging microfluidic systems called surface‐tension‐confined microfluidic (STCM) devices. STCM devices utilize surface energy that can control the movement of fluid droplets. Unlike conventional poly(dimethylsiloxane)‐based microfluidics which confine the movement of fluids by three‐dimensional (3D) microchannels, STCM systems provide two‐dimensional (2D) platforms for microfluidics. A variety of STCM devices have been prepared by various micro‐/nanofabrication strategies. Advantages of STCM devices over conventional microfluidics are significant reduction of energy consumption during device operation, facile introduction of fluids onto 2D microchannels without the use of a micropump, increased flow rate in a special type of STCM device, among others. Thus, STCM devices can be excellent alternatives for certain areas in microfluidics. In this Minireview, fabrication methods, operating modes, and applications of STCM devices are introduced.
From Biomass to Chemicals: Synthesis of Precursors of Biodegradable Surfactants from 5‐Hydroxymethylfurfural
Authors: Arias K. S. , Al‐Resayes Saud I. , Climent Maria J. , Corma Avelino , Iborra Sara 
Published: January 2013

AbstractThe selective acetalization of 5‐hydroxymethylfurfural (HMF) with long‐chain alkyl alcohols has been performed to obtain precursors of molecules with surfactant properties. If direct acetalization of HMF with n‐octanol is performed in the presence of strong acids (homogeneous and heterogeneous catalysts), an increase in etherification versus acetalization occurs. Beta zeolite catalyzes both reactions. However, if the acidity of a zeolite (Beta) was controlled by partial exchange of H+ with Na+, the dioctyl acetal of HMF can be achieved in 95 % yield by transacetalization. It is possible to achieve a high yield in a very short reaction time through a two‐step one‐pot process, which includes the synthesis of the dimethyl acetal of HMF followed by transacetalization with n‐octanol. The one‐pot process could be extended to other alcohols that contain 6–12 carbon atoms to afford 87–98 % yield of the corresponding dialkyl acetal with a selectivity higher than 96 %. The optimized catalyst with an adequate Na content (1.5NaBeta) could be recycled without loss of activity or selectivity.
Time‐Resolved Measurements of Plasma Properties Using Electrostatic Probes in the Cross‐Field Discharge of a Hall Effect Thruster
Authors: Dannenmayer K. , Kudrna P. , Tichý M. , Mazouffre S. 
Published: January 2013

AbstractTime‐resolved measurements of the plasma parameters are performed in the plume of a cross‐field discharge. The plasma potential is measured with a cylindrical Langmuir probe and an emissive probe. The electron temperature and density are measured with a cylindrical Langmuir probe. The cross‐field discharge is maintained in a harmonic oscillation regime to guarantee reproducible conditions for all measurements (© 2013 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Electric Probe Measurements at Edge Region During H‐Mode Discharges in KSTAR
Authors: Bak J.G. , Oh Y.S. , Kim H.S. , Hahn S.H. , Yoon S.W. , Jeon Y.M. , Xiao W.W. , Ko W.H. , Kim W.C. , Kwak J.G. , Woo H.J. , Chung K.S. , the KSTAR project team  
Published: January 2013

AbstractElectrical probe measurements are carried out at the scrape‐off‐layer (SOL) and divertor regions in order to investigate the characteristics of edge plasmas during H‐mode discharges in the Korea Superconducting Tokamak Advanced Research (KSTAR) device. Radial profiles of plasma parameters such as electron temperature Te, plasma density ne, and parallel flow velocity v‖ are measured by using a fast reciprocating Langmuir probe assembly (FRLPA) at the SOL region. From the FRLPA measurements, it is found that the decay length of temperature λTe and that of density λne are 2 ∼ 4 cm and 1 ∼ 3 cm, respectively. The magnitude of v‖ near the last closed flux surface (LCFS) is 4 ∼ 15 km/s. The radial flux due to edge turbulence at the SOL region is investigated by using spectra analysis on electrostatic fluctuation levels such as ion saturation current Ĩis and floating potential $ \tilde{\rm V}_f$ obtained from the FRLPA measurement. The value of the flux is estimated as ∼ 1020 particle m−2 s −1 near the LCFS. The poloidal distribution of the ion saturation current density jis is measured by fixed edge Langmuir probe array (ELPA) at the divertor region, and it is found that the positions of strike points from the ELPA measurement agree well with those reconstructed from the EFIT result using magnetic diagnostic data. From the spectrum analysis on the ELPA measurements at the divertor region during edge localized modes (ELMs) control in the H‐mode discharges, it is observed that the magnitude of $ \tilde{\rm j}_{is}$(ω) near strike point decreases when the ELMs are suppressed or mitigated (© 2013 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
On the Use of a Retarding Field Energy Analyzer for Plasma Flow Analysis
Authors: Fredriksen Å. , Miloch W. J. , Gulbrandsen N. , Mishra L. N. 
Published: January 2013

AbstractMeasurements of plasma flow are of key interest in a number of plasma environments and applications. In laboratory magnetized plasmas, the directional Langmuir or Mach probe is a well‐proven ‘in‐situ’ diagnostic tool to obtain the flow velocity. However, in non‐magnetized or weakly magnetized plasmas, this method does not readily yield reliable velocity measurements, as it has been shown by numerical and experimental studies that the collection of upstream ions to the rearward probe surface can be significant. In this study, we have utilized the analysis of data from 3D PIC simulations [W. J. Miloch, Plasma Phys. Contr. Fusion 52, 124004 (2010)] of ion velocity distributions in the vicinity of a negatively biased object embedded in a collision‐less, source‐free plasma with and without flow. The simulations allow us to study how the grounded probe housing of a retarding field ion energy analyzer (RFEA) affects the distribution of ions and their collection at different angles with flowing, electropositive plasma. We find that an analysis based on derived plasma potential at different angles with the flow, may provide more consistent results than the Mach probe theory in our weakly magnetized case. Comparisons are carried out with RFEA measurements in an inductively coupled helicon plasma (© 2013 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Single cell network profiling assay in bladder cancer
Authors: Covey Todd M. , Vira Manish A. , Westfall Matt , Gulrajani Michael , Cholankeril Michelle , Okhunov Zhamshid , Levey Helen R. , Marimpietri Carol , Hawtin Rachael , Fields Scott Z. , Cesano Alessandra 
Published: January 2013

AbstractThe aim of this study was to assess the feasibility of applying the single cell network profiling (SCNP) assay to the examination of signaling networks in epithelial cancer cells, using bladder washings from 29 bladder cancer (BC) and 15 nonbladder cancer (NC) subjects. This report describes the methods we developed to detect rare epithelial cells (within the cells we collected from bladder washings), distinguish cancer cells from normal epithelial cells, and reproducibly quantify signaling within these low frequency cancer cells. Specifically, antibodies against CD45, cytokeratin, EpCAM, and cleaved‐PARP (cPARP) were used to differentiate nonapoptotic epithelial cells from leukocytes, while measurements of DNA content to determine aneuploidy (DAPI stain) allowed for distinction between tumor and normal epithelial cells. Signaling activity in the PI3K and MAPK pathways was assessed by measuring intracellular levels of p‐AKT and p‐ERK at baseline and in response to pathway modulation; 66% (N = 19) of BC samples and 27% (N = 4) of NC samples met the “evaluable” criteria, i.e., at least 400,000 total cells available upon sample receipt with >2% of cells showing an epithelial phenotype. The majority of epithelial cells detected in BC samples were nonapoptotic and all signaling data were generated from identified cPARP negative cells. In four of 19 BC samples but in none of the NC specimens, SCNP assay identified epithelial cancer cells with a quantifiable increase in epidermal growth factor‐induced p‐AKT and p‐ERK levels. Furthermore, preincubation with the PI3K inhibitor GDC‐0941 reduced or completely inhibited basal and epidermal growth factor‐induced p‐AKT but, as expected, had no effect on p‐ERK levels. This study demonstrates the feasibility of applying SCNP assay using multiparametric flow cytometry to the functional characterization of rare, bladder cancer cells collected from bladder washing. Following assay standardization, this method could potentially serve as a tool for disease characterization and drug development in bladder cancer and other solid tumors. © 2013 International Society for Advancement of Cytometry
Urgent call for the third wish
Authors: Roth Jesse , Holloszy John O. 
Published: January 2013

AbstractThe people afflicted with obesity and its consequences need a menu of low‐cost programmes to mitigate the over‐nutrition and under‐activity that underlie their condition. This editorial commentary points out the multiple merits (and shortcomings) of the Nordic walking – with ski poles – presented in an accompanying article. The Nordic exercise programme is then examined more broadly in the context of the general principles and limitations of exercise programmes – with and without calorie control – as a guide to future innovations. Copyright © 2013 John Wiley & Sons, Ltd.
Overview of reviews in child health: evidence synthesis and the knowledge base for a specific population
Authors: Thomson Denise , Foisy Michelle , Oleszczuk Marta , Wingert Aireen , Chisholm Annabritt , Hartling Lisa 
Published: January 2013

AbstractBackgroundOverviews of reviews are an evolving form of evidence synthesis. The Cochrane Child Health Field has been producing overviews since 2006, during which time the methods that have been used have changed, both due to the development of guidance within The Cochrane Collaboration and to the decisions made by individual author teams. This paper studies the first 29 overviews published in EBCH.ObjectivesTo describe some aspects of the approaches taken in EBCH overviews to producing evidence syntheses relevant to the healthcare needs of children; to highlight the contribution that overviews can make to the knowledge base for treatment for a particular population.MethodsData was extracted on: whether the overview included systematic review (SR) data only, or also data from individual trials not present in the included SRs; name(s) of the Cochrane Review Group (CRG) that prepared the included SRs; topics of the overviews as compared to the topics of the included reviews; age‐subgroup analyses presented in the overviews.ResultsIn 23 overviews, all published in 2012, the authors included trial data as well as SR data; two overviews addressed conditions not explicitly addressed by the included reviews; three overviews included pre‐specified age‐subgroup analyses.DiscussionThe aim of clinical relevance has been achieved by means such as: drawing from reviews produced by multiple CRGs; using SR evidence to explore clinically relevant topics that may not match exactly with the topics covered by the SRs; ensuring that the evidence in overviews is as up to date as possible by redoing searches and including trials not incorporated in the included SRs; and, where permitted by the data, using age‐subgroup analyses to present the data in a way which matches the stages of childhood development.ConclusionOverview authors are dependent on the nature of the data and methods reported in the included SRs. This suggests a need for further study about how SRs could be conducted in order to facilitate the conduct of overviews. Copyright © 2013 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. The Cochrane Collaboration
Commentary on ‘Prophylactic phototherapy for preventing jaundice in preterm or low birth weight infants’
Authors: Davies Mark W. 
Published: January 2013

AbstractThis is a commentary on a Cochrane review, published in this issue of EBCH, first published as:Okwundu CI, Okoromah CAN, Shah PS. Prophylactic phototherapy for preventing jaundice in preterm or low birth weight infants. Cochrane Database of Systematic Reviews 2012, Issue 1. Art. No.: CD007966. DOI: 10.1002/14651858.CD007966.pub2. Copyright © 2013 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. The Cochrane Collaboration
Erratum: The Cochrane Library and treatment of patent ductus arteriosus: an overview of reviews
Authors: Harrold J. , Lacaze‐Masmonteil T. , Hartling L. , Oleszczuk M. 
Published: January 2013

AbstractThe above article was published in EBCH 7:1185–1195 (2012). DOI:10.1002/ebch.1855 Copyright © 2013 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. The Cochrane Collaboration
Relative performance of hybrid nestlings inFicedulaflycatchers: a translocation experiment
Authors: Vallin Niclas , Nonaka Yuki , Feng Jue , Qvarnström Anna 
Published: January 2013

AbstractEcological speciation predicts that hybrids should experience relatively low fitness in the local environments of their parental species. In this study, we performed a translocation experiment of nestling hybrids between collared and pied flycatchers into the nests of conspecific pairs of their parental species. Our aim was to compare the performance of hybrids with purebred nestlings. Nestling collared flycatchers are known to beg and grow faster than nestling pied flycatchers under favorable conditions, but to experience higher mortality than nestling pied flycatchers under food limitation. The experiment was performed relatively late in the breeding season when food is limited. If hybrid nestlings have an intermediate growth potential and begging intensity, we expected them to beg and grow faster, but also to experience lower survival than pied flycatchers. In comparison with nestling collared flycatchers, we expected them to beg and grow slower, but to survive better. We found that nestling collared flycatchers indeed begged significantly faster and experienced higher mortality than nestling hybrids. Moreover, nestling hybrids had higher weight and tended to beg faster than nestling pied flycatchers, but we did not detect a difference in survival between the latter two groups of nestlings. We conclude that hybridFicedulanestlings appear to have a better intrinsic adaptation to food limitation late in the breeding season compared with nestling collared flycatchers. We discuss possible implications for gene flow between the two species.
The Reactivity of Molybdenum Pentachloride with Ester Molecules: Ester Activation, Metal Reduction, and Synthesis of 1D Coordination Polymers
Authors: Dolci Sara , Marchetti Fabio , Pampaloni Guido , Zacchini Stefano 
Published: January 2013

AbstractThe reactions of Mo2Cl10 (1) with stoichiometric amounts of a variety of molecules containing the ester functionality in anhydrous noncoordinating solvents afforded metal compounds, which were isolated in the solid state and characterized. The 1:4 molar reactions of 1 with methyl formate (HCO2Me), methyl methoxyacetate (MeOCH2CO2Me) and methyl D,L‐lactate [D,L‐HOCH(Me)CO2Me] gave the dinuclear complex [MoOCl3{O=C(H)OMe}]2 (2) and the mononuclear complexes MoOCl3[κ2‐O=C(OMe)CH2OMe] (6a) and MoOCl3[κ2‐O=C(OMe)CH(Me)OH] (6b), respectively. According to NMR/GC–MS analyses, activation of the ester moiety in part of the organic material took place in distinct cases. The molybdenum(IV) 1D coordination polymers [MoCl4‐κ2‐{trans‐(CO2R)CH=CH(CO2R)}]n (R = Me, 3a; R = Et, 3b) were prepared by treatment of 1 with 2 equiv. of alkyl fumarates. In contrast, the mononuclear MoIV complexes MoCl4[κ2‐CH2(CO2Me)2] (4) and MoCl4[κ2‐{cis‐(CO2Me)CH=CH(CO2Me)}] (5) were obtained from 1/CH2(CO2Me)2 and 1/cis‐maleate, respectively. The molecular structures of 2, 3a, 3b, 4, 6a and 6b were ascertained by X‐ray diffraction studies.
Oxidative Dry‐Reforming of Biogas: Reactor Design and SOFC System Integration
Authors: Jahn Matthias , Heddrich Marc , Weder Aniko , Reichelt Erik , Lange Rüdiger 
Published: January 2013

AbstractBiogas is an attractive fuel for solid oxide fuel cell applications because of the high CO2 content. Its composition allows a high electrical efficiency without adding external water to the system. Because of the CO2 reforming reaction only a very small amount of air is needed for partial oxidation, which is why the process could be called oxidative dry‐reforming. Herein, this concept is demonstrated by a thermodynamic analysis of the process and experimental system and component results. In order to realize a high yield of electrical power from the SOFC stack, a large flow of chemical energy into the stack is needed. To achieve this goal the efficiency of the reforming process is essential. With optimized reforming conditions it is possible to increase the chemical energy content of the fuel by adding an ample amount of heat to the reforming step. To achieve this in practice, the necessary heat flow to the reformer has to be calculated for a given operating temperature. Based on these thermodynamic calculations a reactor was built and tested. After successful laboratory tests the reactor was integrated into an SOFC system, where the necessary heat for the reforming step was supplied by the afterburner. The results of the component tests were verified under system conditions. Based on this system concept a high value for the electrical efficiency (ηel>0.5) of the system was achieved.