bluuebunny/crossref_metadata_2025_split huggingface dataset:
Efficient group‐based authentication protocol for location‐based service discovery in intelligent transportation systems
Authors: Abrougui Kaouther , Boukerche Azzedine 
Published: February 2013

ABSTRACTIntelligent transportation systems have attracted many researchers. These latter have invested much effort to develop many applications and services mainly for vehicular systems. Services can be classified as safety or convenience services. A service discovery mechanism is needed to permit the discovery and the interaction with the existing services. However, so far security issues for service discovery in vehicular systems have not been widely considered, mainly for the convenience type of applications. Thus, a secure service discovery and communication protocol is necessary to prevent from many attacks and malicious processes in the vehicular system. In this paper, we investigate the possible attacks that can occur during the service discovery and communication processes. Then, we present our proposed group‐based authentication scheme for secure service discovery and communication in vehicular systems. Our proposed scheme is mainly dedicated for the convenience type of applications. We discuss the security requirements achieved by our proposed protocol and we report on its performance evaluation. We prove through our extensive set of simulations that our proposed scheme achieves a high success rate for the secure discovery of services, while maintaining the scalability of the network and low discovery delays. Copyright © 2013 John Wiley & Sons, Ltd.
Boron Nitride Nanotubes: Biocompatibility and Potential Spill‐Over in Nanomedicine
Authors: Ciofani Gianni , Danti Serena , Genchi Giada Graziana , Mazzolai Barbara , Mattoli Virgilio 
Published: February 2013

AbstractBoron nitride nanotubes (BNNTs) represent an innovative and extremely intriguing class of nanomaterials. Thanks to their special chemical and physical characteristics, they have already found a large number of applications in the field of nanotechnology, and recent studies have shown their possible exploitation in the biomedical domain, both as nanocarriers and, more interestingly, as nanotransducers. In this review, the latest findings on the interactions between BNNTs and living systems are summarized, starting with the major issues of their stabilization in physiological media and their functionalization with bioactive molecules. Thereafter the biocompatibility data which have so far been made available are discussed, and the need for further extensive and standardized tests is highlighted. Finally, the appealing diagnostic and therapeutic opportunities offered by BNNT‐based systems are described, envisioning the potential spill‐over effects of such 'smart' and 'active' nanoparticles in nanomedicine.
Tuning the Stability of Graphene Layers by Phthalocyanine‐Based oPPV Oligomers Towards Photo‐ and Redoxactive Materials
Authors: Brinkhaus Linda , Katsukis Georgios , Malig Jenny , Costa Rubén D. , Garcia‐Iglesias Miguel , Vázquez Purificación , Torres Tomás , Guldi Dirk M. 
Published: February 2013

AbstractIn contrast to pristine zinc phthalocyanine (1), zinc phthalocyanine based oPPV‐oligomers (2–4) of different chain lengths interact tightly and reversibly with graphite, affording stable and finely dispersed suspensions of mono‐ to few‐layer graphene—nanographene (NG)—that are photoactive. The p‐type character of the oPPV backbones and the increasing length of the oPPV backbones facilitate the overall π–π interactions with the graphene layers. In NG/2, NG/3, and NG/4 hybrids, strong electronic coupling between the individual components gives rise to charge transfer from the photoexcited zinc phthalocyanines to NG to form hundreds of picoseconds lived charge transfer states. The resulting features, namely photo‐ and redoxactivity, serve as incentives to construct and to test novel solar cells. Solar cells made out of NG/4 feature stable and repeatable photocurrent generation during several ‘on‐off’ cycles of illumination with monochromatic IPCE values of around 1%.
Bifunctional Graphene/γ‐Fe2O3 Hybrid Aerogels with Double Nanocrystalline Networks for Enzyme Immobilization
Authors: Chen Liang , Wei Bin , Zhang Xuetong , Li Chun 
Published: February 2013

AbstractHighly porous hosting materials with conducting (favorable to electron transfer) and magnetic (favorable to product separation) bicontinuous networks should possess great potentials for immobilization of various enzymes in the field of biocatalytic engineering, but the synthesis of such materials is still a great challenge. Herein, bifunctional graphene/γ‐Fe2O3 hybrid aerogels with quite low density (30–65 mg cm−3), large specific surface area (270–414 m2 g−1), high electrical conductivity (0.5–5 × 10−2 S m−1), and superior saturation magnetization (23–54 emu g−1) are fabricated. Single networks of either graphene aerogels or γ‐Fe2O3 aerogels are obtained by etching of the hybrid aerogels with acid solution or calcining of the hybrid aerogels in air, indicative of the double networks of the as‐synthesized graphene/γ‐Fe2O3 hybrid aerogels for the first time. The resulting bifunctional aerogels are used to immobilize β‐glucuronidase for biocatalytic transformation of glycyrrhizin into glycyrrhetinic acid monoglucuronide or glycyrrhetinic acid, with high biocatalytic activity and definite repeatability.
Automatic Segmentation of Method Code into Meaningful Blocks: Design and Evaluation
Authors: Wang Xiaoran , Pollock Lori , Vijay‐Shanker K. 
Published: February 2013

SUMMARYGood programming practice and guidelines suggest that programmers use both vertical and horizontal spacing to visibly delineate between code segments that represent different algorithmic steps or high‐level actions. Unfortunately, programmers do not always follow these guidelines. Editors and integrated development environments (IDEs) can easily indent codes based on syntax, but they do not currently support automatic blank line insertion, which presents more significant challenges involving the semantics.This paper presents and evaluates a heuristic solution to the automatic blank line insertion problem by leveraging both program structure and naming information to identify ‘meaningful blocks’, consecutive statements that logically implement a high‐level action. Our tool, SEGMENT, takes as input a Java method and outputs a segmented version that separates meaningful blocks by vertical spacing. We report on several studies involving human judgments to evaluate the effectiveness of the automatic blank line insertion algorithm, for different size methods and for different levels of programmer expertise. The results indicate strong positive overall opinion of SEGMENT's effectiveness in comparison with both developer‐written blank lines and blank lines inserted by newcomers to the code. The results vary only slightly among short and long methods, and among novice and advanced programmers. SEGMENT assists in making users obtain an overall picture of a method's actions and comprehend it quicker as well as provides hints for internal documentation placement. Copyright © 2013 John Wiley & Sons, Ltd.
Etiology and Outcome of Acute Pancreatitis in Children in Kashmir (India). An Endemic Area of Hepatobiliary Ascariasis
Authors: Javid Gul , Zargar Showkat , Shah Altaf , Shoukat Abid , Iqball Asif , Gupta Amit 
Published: February 2013

AbstractBackgroundThe purpose of the present study was to determine the etiology, management, and outcome of acute pancreatitis (AP) in children in an endemic area of hepatobiliary ascariasis (HBA).MethodsThis was a prospective, hospital‐based study over a 9‐year period that included 156 children younger than 12 years of age who had a diagnosis of AP.ResultsOf the 156 patients, 71 were boys and 85 were girls with a mean age of 8.4 ± 1.5 years (range 3–12 years). The various factors contributing to AP were biliary ascariasis in 93 cases (60 %), gallstones 16 (10 %), trauma 5 (3 %), choledochal cyst 4 (3 %), impacted bile duct stone 3 (2 %), and gallbladder sludge 2 (1 %). Idiopathic group 33 cases (21 %). Diagnosis was based on clinical picture, abdominal ultrasonography, and elevated serum amylase level. Pancreatitis was mild in 113 (72 %) patients and severe in 43 (28 %). With conservative therapy, 123 patients (79 %) improved, whereas the remaining 33, who had intractable abdominal pain, cholangitis, or worsening cholecystitis, underwent emergency endoscopic retrograde cholangiopancreatography for removal of worms (26 patients) and stones in the bile duct (7 patients). Bile duct stones were extracted in all 7 patients with that condition, and worms were extracted from 23 of the 26 patients with ascariasis. Emergency surgery was performed in five patients. Three patients died. Pancreatitis recurred in 16 patients due to HBA.ConclusionsPancreatitis is not uncommon in children. Ascariasis is a leading cause of AP in endemic areas. Patients usually respond to conservative management, but endoscopic treatment is effective. Surgery is rarely required.
An Investigation of the Dynamic Processes Promoting Citizen Participation
Authors: Foster-Fishman Pennie G. , Collins Charles , Pierce Steven J. 
Published: February 2013

AbstractThis study expanded the citizen participation literature by examining the dynamic nature of citizen participation and the extent to which the factors associated with citizen participation may be moderated by resident leadership status. Longitudinal survey data collected from 542 residents in one small Midwestern city implementing a community change initiative provide some insight into the challenges surrounding the promotion of an active citizenry. Within this one community, citizenship behaviors of emergent resident leaders and residents uninterested in a leadership role were influenced, to some extent, by different factors and the importance of these factors shifted in only a 2 years time span. Future research is needed to determine if the dynamics uncovered in this study were due to the initiative or to the nature of citizen participation processes.
Dromions of flexural-gravity waves
Authors: Alam Mohammad-Reza 
Published: February 2013

AbstractHere we show that weakly nonlinear flexural-gravity wave packets, such as those propagating on the surface of ice-covered waters, admit three-dimensional fully localized solutions that travel with a constant speed without dispersion or dissipation. These solutions, that are formed at the intersection of line-soliton mean-flow tracks, have exponentially decaying tails in all directions and are called dromions in contrast to lumps that decay only algebraically. We derive, by asymptotic expansion and assuming multiple scales for spatial and temporal variations, the three-dimensional weakly nonlinear governing equations that describe the coupled motion of the wavepacket envelope and the underlying mean current. We show that in the limit of long waves and strong flexural rigidity these equations reduce to a system of nonlinear elliptic–hyperbolic partial differential equations similar to the Davey–Stewartson I (DSI) equation, but with major differences in the coefficients. Specifically, and contrary to DSI equations, the elliptic and hyperbolic operators in the flexural-gravity equations are not canonical resulting in complications in analytical considerations. Furthermore, standard computational techniques encounter difficulties in obtaining the dromion solution to these equations owing to the presence of a spatial hyperbolic operator whose solution does not decay at infinity. Here, we present a direct (iterative) numerical scheme that uses pseudo-spectral expansion and pseudo-time integration to find the dromion solution to the flexural-gravity wave equation. Details of this direct simulation technique are discussed and properties of the solution are elaborated through an illustrative case study. Dromions may play an important role in transporting energy over the ice cover in the Arctic, resulting in the ice breaking far away from the ice edge, and also posing danger to icebreaker ships. In fact we found that, contrary to DSI dromions that only exist in water depths of less than 5 mm, flexural-gravity dromions exist for a broad range of ice thicknesses and water depths including values that may be realized in polar oceans.
Optimal Taylor–Couette flow: direct numerical simulations
Authors: Ostilla Rodolfo , Stevens Richard J. A. M. , Grossmann Siegfried , Verzicco Roberto , Lohse Detlef 
Published: February 2013

AbstractWe numerically simulate turbulent Taylor–Couette flow for independently rotating inner and outer cylinders, focusing on the analogy with turbulent Rayleigh–Bénard flow. Reynolds numbers of $R{e}_{i} = 8\times 1{0}^{3} $ and $R{e}_{o} = \pm 4\times 1{0}^{3} $ of the inner and outer cylinders, respectively, are reached, corresponding to Taylor numbers $Ta$ up to $1{0}^{8} $. Effective scaling laws for the torque and other system responses are found. Recent experiments with the Twente Turbulent Taylor–Couette (${T}^{3} C$) setup and with a similar facility in Maryland at very high Reynolds numbers have revealed an optimum transport at a certain non-zero rotation rate ratio $a= - {\omega }_{o} / {\omega }_{i} $ of about ${a}_{\mathit{opt}} = 0. 33$. For large enough $Ta$ in the numerically accessible range we also find such an optimum transport at non-zero counter-rotation. The position of this maximum is found to shift with the driving, reaching a maximum of ${a}_{\mathit{opt}} = 0. 15$ for $Ta= 2. 5\times 1{0}^{7} $. An explanation for this shift is elucidated, consistent with the experimental result that ${a}_{\mathit{opt}} $ becomes approximately independent of the driving strength for large enough Reynolds numbers. We furthermore numerically calculate the angular velocity profiles and visualize the different flow structures for the various regimes. By writing the equations in a frame co-rotating with the outer cylinder a link is found between the local angular velocity profiles and the global transport quantities.
Freeze-dried jaboticaba peel powder improves insulin sensitivity in high-fat-fed mice
Authors: Dragano Nathalia R. V. , Marques Anne y Castro , Cintra Dennys E. C. , Solon Carina , Morari Joseane , Leite-Legatti Alice V. , Velloso Lício A. , Maróstica-Júnior Mário R. 
Published: February 2013

The peel of the native Brazilian fruit jaboticaba is rich in anthocyanins, which are known for their anti-obesity effects in animal models. The aim of the present study was to evaluate the effects of freeze-dried jaboticaba peel powder (FDJPP) on a number of metabolic parameters in a model of diet-induced obesity. Mice (n8 per group) were initially fed on a high-fat diet (HFD, 35 % w/w) for 4 weeks and then switched to a HFD supplemented with FDJPP (1, 2 or 4 % w/w) for an additional 6 weeks. Energy intake, weight loss, glucose tolerance, insulin resistance and lipid profile were determined, and the results were evaluated using ANOVA and Tukey's tests. The FDJPP exerted no protective effect on HFD-induced weight gain, hyperleptinaemia and glucose intolerance. However, the supplementation was effective to reduce insulin resistance, as evidenced in the insulin tolerance test, and subsequently confirmed by improved signal transduction through the insulin receptor/insulin receptor substrate-1/Akt/forkhead box protein pathway and by the attenuation of HFD-induced inflammation in the liver, verified by lower expressions of IL-1β and IL-6 and decreased phosphorylated IκB-α protein levels in all jaboticaba-treated mice. These results suggest that FDJPP may exert a protective role against obesity-associated insulin resistance.
Chronic stressors and trauma: prospective influences on the course of bipolar disorder
Authors: Gershon A. , Johnson S. L. , Miller I. 
Published: February 2013

BackgroundExposure to life stress is known to adversely impact the course of bipolar disorder. Few studies have disentangled the effects of multiple types of stressors on the longitudinal course of bipolar I disorder. This study examines whether severity of chronic stressors and exposure to trauma are prospectively associated with course of illness among bipolar patients.MethodOne hundred and thirty-one participants diagnosed with bipolar I disorder were recruited through treatment centers, support groups and community advertisements. Severity of chronic stressors and exposure to trauma were assessed at study entry with in-person interviews using the Bedford College Life Event and Difficulty Schedule (LEDS). Course of illness was assessed by monthly interviews conducted over the course of 24 months (over 3000 assessments).ResultsTrauma exposure was related to more severe interpersonal chronic stressors. Multiple regression models provided evidence that severity of overall chronic stressors predicted depressive but not manic symptoms, accounting for 7.5% of explained variance.ConclusionsOverall chronic stressors seem to be an important determinant of depressive symptoms within bipolar disorder, highlighting the importance of studying multiple forms of life stress.
Lessons learned from the psychosis high-risk state: towards a general staging model of prodromal intervention
Authors: Fusar-Poli P. , Yung A. R. , McGorry P. , van Os J. 
Published: February 2013

BackgroundThe past two decades have seen exponential clinical and research interest in help-seeking individuals presenting with potentially prodromal symptoms for psychosis. However, the epidemiological validity of this paradigm has been neglected, limiting future advancements in the field.MethodWe undertook a critical review of core epidemiological issues underlying the clinical high-risk (HR) state for psychosis and which model of prodromal intervention is best suited for mental health.ResultsThe HR state for psychosis model needs refining, to bring together population-based findings of high levels of psychotic experiences (PEs) and clinical expression of risk. Traditionally, outcome has been attributed to ‘HR criteria’ alone rather than taking into account sampling strategies. Furthermore, the exclusive focus on variably defined ‘transition’ obscures true variation in the slow and non-linear progression across stages of psychopathology. Finally, the outcome from HR states is variable, indicating that the underlying paradigm of ‘schizophrenia light progressing to schizophrenia’ is inadequate.ConclusionsIn the general population, mixed and non-specific expression of psychosis, depression, anxiety and subthreshold mania is common and mostly transitory. When combined with distress, it may be considered as the first, diagnostically neutral stage of potentially more severe psychopathology, which only later may acquire a degree of diagnostic specificity and possible relative resistance to treatment. Therefore, rather than creating silos of per-disorder ultra-HR syndromes, an early intervention focus on the broad syndrome of early mental distress, requiring phase-specific interventions, may be more profitable.
Cigarette smoking and cannabis use are equally strongly associated with psychotic-like experiences: a cross-sectional study in 1929 young adults
Authors: van Gastel W. A. , MacCabe J. H. , Schubart C. D. , Vreeker A. , Tempelaar W. , Kahn R. S. , Boks M. P. M. 
Published: February 2013

BackgroundCannabis use is associated with increased risk for psychotic-like experiences (PLEs) and psychotic disorders. It remains unclear whether this relationship is causal or due to confounding.MethodA total of 1929 young adults aged 18–30 years participated in a nationwide internet-based survey in The Netherlands and gave information on demographics, substance use and parental psychiatric illness and completed the Community Assessment of Psychic Experiences (CAPE).ResultsCigarette smoking and cannabis use were equally strongly associated with the frequency of PLEs in a fully adjusted model (β = 0.098 and 0.079 respectively,p < 0.05). Cannabis use was associated with distress from PLEs in a model adjusted for an elaborate set of confounders excluding smoking (β = 0.082,p < 0.05). However, when cigarette smoking was included in the model, cannabis use was not a significant predictor of distress from PLEs. Cigarette smoking remained associated with distress from PLEs in a fully adjusted model (β = 0.107,p < 0.001).ConclusionsSmoking is an equally strong independent predictor of frequency of PLEs as monthly cannabis use. Our results suggest that the association between moderate cannabis use and PLEs is confounded by cigarette smoking.
Trends in annual incidence of methicillin-resistantStaphylococcus aureus(MRSA) infection in HIV-infected and HIV-uninfected patients
Authors: DELORENZE G. N. , HORBERG M. A. , SILVERBERG M. J. , TSAI A. , QUESENBERRY C. P. , BAXTER R. 
Published: February 2013

SUMMARYWe describe trends in incidence rates of methicillin-resistantStaphylococcus aureus(MRSA) in HIV-infected and HIV-uninfected patients enrolled in a large northern California Health Plan, and the ratio of MRSA to methicillin-susceptibleS. aureus(MSSA) case counts. Between 1995 and 2010, 1549 MRSA infections were diagnosed in 14060 HIV-infected patients (11·0%) compared to 89546 MRSA infections in 6597396 HIV-uninfected patients (1·4%) (P = 0·00). A steady rise in MRSA infection rates began in 1995 in HIV-uninfected patients, peaking at 396·5 infections/100000 person-years in 2007. A more rapid rise in MRSA infection rates occurred in the HIV-infected group after 2000, peaking at 3592·8 infections/100000 in 2005. A declining trend in MRSA rates may have begun in 2008–2009. Comparing the ratio of MRSA to MSSA case counts, we observed that HIV-infected patients shouldered a greater burden of MRSA infection during most years of study follow-up compared to HIV-uninfected patients.
Tuberculosis in captive Asian elephants (Elephas maximus) in Peninsular Malaysia
Authors: ONG B. L. , NGEOW Y. F. , RAZAK M. F. A. ABDUL , YAKUBU Y. , ZAKARIA Z. , MUTALIB A. R. , HASSAN L. , NG H. F. , VERASAHIB K. 
Published: February 2013

SUMMARYA cross-sectional study was conducted from 10 January to 9 April 2012, to determine the seroprevalence of tuberculosis (TB) of all captive Asian elephants and their handlers in six locations in Peninsular Malaysia. In addition, trunk-wash samples were examined for tubercle bacillus by culture and polymerase chain reaction (PCR). For 63 elephants and 149 elephant handlers, TB seroprevalence was estimated at 20·4% and 24·8%, respectively. From 151 trunk-wash samples, 24 acid-fast isolates were obtained, 23 of which were identified byhsp65-based sequencing as non-tuberculous mycobacteria. TheMycobacterium tuberculosis-specific PCR was positive in the trunk-wash samples from three elephants which were also seropositive. Conversely, the trunk wash from seven seropositive elephants were PCR negative. Hence, there was evidence of active and latent TB in the elephants and the high seroprevalence in the elephants and their handlers suggests frequent, close contact, two-way transmission between animals and humans within confined workplaces.
Hidden substance: mental disorder as a challenge to normatively neutral accounts of autonomy
Authors: Freyenhagen Fabian , O'Shea Tom 
Published: February 2013

AbstractMental capacity and autonomy are often understood to be normatively neutral – the only values or other norms they may presuppose are those the assessed person does or would accept. We show how mental disorder threatens normatively neutral accounts of autonomy. These accounts produce false positives, particularly in the case of disorders (such as depression, anorexia nervosa and schizophrenia) that affect evaluative abilities. Two normatively neutral strategies for handling autonomy-undermining disorder are explored and rejected: a blanket exclusion of mental disorder, and functional tests requiring consistency, expression of identity, reflective non-alienation or lack of compulsion. Finally, we suggest ways in which substantivist alternatives to neutrality can be made more promising through increased transparency, democratic contestability of conditions for capacity and autonomy, and a historically sensitive caution concerning restrictions of liberty.