bluuebunny/crossref_metadata_2025_split huggingface dataset:
Detección y Cuantificación de Microplásticos en el Sistema de Agua Potable de la ciudad del Cusco
Authors: Lara  Díaz del Olmo Zulma , Mostajo Zavaleta Martha , Ochoa Cámara María Luisa 
Published: July 2024

Se detectó y cuantifico microplásticos en aguas de la laguna de Piuray , que abastece a la planta de Santa Ana, donde se realiza el tratamiento de agua, para consumo de la población Cusqueña, así como en agua de grifos domiciliarios del centro poblado de Chinchero. El sedimento de las muestras de agua se sometió a digestión oxidativa, para extraer los microplásticos, se utilizó peróxido de hidrogeno al 20 %. (Nuelle et. al., 2014), permitiendo así la separación de los plásticos por flotación y separación del sobrenadante (Thonson et. al.2004).), el volumen final de cada muestra fue filtrado. La mayor cantidad de microplásticos se detectó en la muestra de agua proveniente de la Caseta de Guardianía - Zona Piuray, ( un promedio 164 microplasticos / campo), de los cuales el 94 % de micro plástico corresponde a la tipología de fragmento, y el 6 % de fibra, de acuerdo al análisis de Espectroscopia infrarroja – transformada de Fourier se ha encontrado polietileno de baja densidad y polipropileno. En la zona de Pongobamba a 50 ms de la orilla se ha encontrado la menor cantidad de microplásticos, 14/ campo, de los cuales el 71.4 % corresponde a la tipología de fibra y el 29 % a la de fragmento. En las muestras de agua de la laguna de Piuray se ha encontrado 76 % de microplásticos con tipología de fragmento y 24 % de fibra. No se detectó micro plásticos en agua de grifo de viviendas del centro poblado de Chinchero
Efecto tóxico de cafeína, dicromato de potasio y metomilo en la germinación de Vicia faba
Authors: Jordán Quispe Karen , Muñiz Duran Julia 
Published: July 2024

La presente investigación, tuvo por objetivo evaluar efetos tóxicos y genotóxico en la germinación de Vicia faba a través de pruebas toxicológicas (bioensayos) en el crecimiento del sistema radicular y del coleóptilo para medir toxicidad germinativa y el ensayo de micronúcleos para determinar la genotoxicidad a nivel del material genético, para tal fin los compuestos tóxicos seleccionados fueron, metomilo, dicromato de potasio y como control positivo la cafeína, compuestos de uso frecuente en la agricultura e industria textil, actividades propias de las zonas andinas en Perú. Las concentraciones fueron determinadas a través de un aprueba piloto 500, 1000, 2000, 4000 y 8000 ppm, los datos obtenidos permitieron determinar la CL50 mediante el programa EPA PROBIT-1,5. Para la elongación del sistema radicular y coleóptilo se consideró la relación dosis–efecto en la germinación a las diferentes concentraciones establecidas y para la genotoxicidad se observó la presencia o ausencia de micronúcleos, obteniéndose una CL50 en cafeína, dicromato de potasio, metomilo de 2172, 8 ppm, 3286,9 ppm y 5174, 6 ppm respectivamente. En cuanto a la genotoxicidad el recuento de micronúcleos realizado en las radículas de Vicia faba determinó una prevalencia porcentual entre 3 % y 9.75 % en las tres primeras concentraciones 1000, 2000 y 4000 ppm, a 8000 ppm las células presentaron lisis. Por lo tanto, los resultados obtenidos evidenciaron efectos tóxicos y genotóxicos en Vicia faba causado por metomilo, dicromato de potasio y cafeína.
Investigación en encinares mexicanos sujetos a instrumentos de políticas públicas de conservación y uso
Authors: Rosaliano-Evaristo Rubén , Ávila-Akerberg Víctor , Gómez-Demetrio William , Sotelo-Núñez Esthela I. 
Published: July 2024

Introducción. El deterioro de los ecosistemas forestales ha impulsado la adopción de mecanismos para su conservación y uso sostenible.
Objetivo: Identificar el estado del conocimiento en torno a los bosques de encino en México, asociados a mecanismos de políticas públicas de conservación y uso: Áreas Naturales Protegidas (ANP), Pago por Servicios Ambientales (PSA) y Manejo Forestal Comunitario (MFC).
Material y métodos: Se utilizó el marco metodológico de búsqueda, evaluación, síntesis y análisis. La información se obtuvo en las plataformas de Scopus, Scielo y Redalyc. Los documentos encontrados se sometieron a un proceso de inclusión y exclusión de acuerdo con criterios de temporalidad y fuentes primarias.
Resultados y discusión: Se identificaron 662 investigaciones de las que se analizaron 37 publicadas en el periodo 2000-2022. De estas, 17 se relacionan con el MFC y estudian características de las comunidades forestales y efectos socioecológicos; 13 abordaron temáticas relacionadas con ANP, enfocadas en biología de la conservación de flora y fauna; y dos contribuciones se centraron en el PSA, las cuales destacan los análisis y evaluación de los efectos socioambientales. Por último, cinco investigaciones involucran a dos y tres de los instrumentos mencionados. Conclusiones: El análisis de los bosques de encino en relación con políticas públicas de conservación y aprovechamiento ha experimentado notable aumento. Los estudios indican que este tipo de políticas contribuyen a reducir el riesgo de cambios adversos en estos bosques. Debido a la importancia ecológica, social y económica de los encinares, se sugiere abordar su comprensión desde perspectivas como el enfoque de los sistemas
socioecológicos y la transdisciplina.
Motivational evaluation of food security programs in Central Java, Indonesia
Authors: Sutrisno Joko , Marwanti Sri , Anugrah Putri Hilda , Nadifta Ulfa Amalia , Nurhidayati Indah 
Published: July 2024

Purpose. This research aims to determine the level of motivation of the target audience (group, farmer associations (Gapoktan) or farm) and factors that influence motivation in participating in the implementation of the Toko Tani Indonesia (TTI) program.
Methodology / approach. This research was conducted by direct interview method with all Farmer Shops and Gapoktan / Poktan in three regions in Central Java, namely Semarang City, Sukoharjo Regency, and Grobogan Regency. Data collection is carried out using a questionnaire with a Likert scale measurement. The methods used for analysis are descriptive statistics and inferential statistics using the partial least squares structural equation modeling (SEM-PLS).
Results. The results show that the motivation level of TTI actors is high, meaning that program implementers in the field have a substantial boost from social, economic, and socio-economic factors. These results indicate that this food security program can be implemented well because field implementers can feel the overall positive impact. Furthermore, in SEM analysis, factors influencing motivation show that mediating variables for capacity and perception significantly correlate with motivation. Meanwhile, the government support and characteristics variables have a significant relationship with the mediation variables.
Originality / scientific novelty. The novelty of this study is the analysis of research conducted on the motivation of food security program actors with the object of study that is rarely used as research, namely the PUPM Program through the Indonesian Farmer Shop (TTI). This program aims to stabilise prices and solve supply chain problems in Indonesia. This is so that rice prices do not harm farmers or the community. Therefore, the value of this study is that it attempts to answer the question of how to influence the motivation and sustainability of the program so that the government, together with the community and stakeholders, can ensure national food security.
Practical value / implications. The research results can be a recommendation for related parties and policymakers to continue implementing the TTI program to implement national food security. This study shows that the government can use these factors to maintain and increase motivation to maximise program implementation; so that the objectives of this program can be implemented and the program can be continued for the following periods.
Change of adaptability to increase employee performance in state-owned enterprises in agriculture
Authors: Pramudito Dicky , Suharnomo  , Mahfudz  
Published: July 2024

Purpose. The main purpose of this research is to summarise the descriptive analysis of change impact and evaluate the impact of change adaptability on employee performance in state-owned enterprises (SOE) in Indonesian agriculture.
Methodology / approach. This study integrates theoretical perspectives on change management, adaptability, organisational learning, and employee performance. The model was tested at Indonesian agricultural state-owned enterprise which consists of 14 companies around Indonesia. The sample comprised 373 employees in middle management. Descriptive analysis and probability sampling were used with a disproportionate stratified random sampling technique, Likert questionnaire scale, and indexing with three box methods and Structural Equation Model in Analysis of the Moment Structure program used for the research model.
Results. The findings suggest that learning from past change has a positive and significant effect on employee performance, but the adaptability of change and memories of change have a non-significant effect on employee performance. The models fit the Goodness of Fit Criteria (GFI = 0.934; AGFI = 0.911; CMIN/DF = 1.918; RMSEA = 0.050; TLI = 0.982; CFI = 0.985; NFI = 0.969; p-Bollen-Stine Bootstrap = 0.058); and also based on the descriptive analysis, changes in technology is the most significant changes that affect on company.
Originality / scientific novelty. Several studies in the literature include the relationship between change readiness, and adaptability on employee performance, nevertheless, this study further builds and examines the construct of adaptability of change, memories of change, learning from the last change, identifying employee performance scales that should be paid more attention to and the significance among them.
Practical value / implications. Based on the study’s findings, the role of learning from past changes in affecting employee performance in Indonesian agricultural state-owned enterprise provides a new and significant insight into the research literature on change adaptability and the challenges facing these companies. It has practical implications for managers and leaders confronting organisational change management in Indonesia, enhancing employee performance, and realising sustainable agriculture.
Students’ interest in agribusiness as a future career
Authors: Pervez A K M Kanak , Kabir Md Shahriar , Saha Amitav , Hossain Md Ikbal , Haque Md Armanul 
Published: July 2024

Purpose. This study was conducted among Bangladeshi undergraduate agricultural students to see how likely they were to launch their agribusinesses after awarding Bachelor’s degrees.
Methodology / approach. As an agricultural country, agribusiness among the students is increasingly important. To achieve the purpose, we selected undergraduate students from the University of Rajshahi as the respondents. Agriculture, Fisheries, and Veterinary Science students were surveyed to determine their interest in starting an agribusiness (opening their own enterprises) after graduation. Questionnaire data were subjected to a logit regression analysis.
Results. Most students come from rural backgrounds and many work in family farming either directly or indirectly, only a small percentage of them (29.6 %) want to start an agribusiness after graduation. Most students think working for the Government or providing other services is safer than doing business. Except for students whose families had large landholdings, students were not interested in becoming agribusiness entrepreneurs, although female students were more curious than males. The students perceived agribusiness as too risky and preferred civil service or other service sector employment over any business. If they were to set up such companies, they would be the most interested in fruits and vegetables, feed mills, beef, floriculture, and fisheries. Part of the reason for this disinclination to entrepreneurship is South Asian culture, which values security over independence, although agriculture, where the product is perishable, is risky.
Originality / scientific novelty. Over the last 10 years, there has been a decline in total agricultural employment despite a rise in the youth unemployment rate. Encouraging these young people to go into agribusiness, we can reduce unemployment and increase agricultural productivity. But, regarding the interest of young people in Bangladesh in agribusiness, there is no published material. Thus, this study is the first in Bangladesh to assess the interest of agricultural students in starting an agribusiness and describe its determinants.
Practical value / implications. The state wants to encourage agribusiness, but does not have a policy to achieve the goal and universities do not even teach this subject to agriculture graduates. If the government is serious about expanding agricultural entrepreneurship, it will have to invest in agribusiness to reduce its risk: in agricultural mechanisation, better rural transport and infrastructure, insurance for agricultural enterprises, mentors to impart business skills and advice, and a national capital fund to invest in such enterprises and finance them by capital rather than by debt.
Subjetividades políticas emergentes en el trabajo uruguayo. Un enfoque teórico comparado
Authors: Pucci Francisco , Menéndez Victoria , Cutro Dumas Camila 
Published: July 2024

El trabajo aborda los procesos de construcción de subjetividades situadas en el trabajo. Con este objetivo, se plantea la discusión entre la perspectiva configuracionista desarrollada por De la Garza y la propuesta marxista de Modonesi, en la cual se abordan los procesos de producción subjetividades políticas. Ambas desarrollan miradas procesuales de conformación de subjetividades, invitando a pensar en su carácter dinámico y no lineal. Este campo fue tematizado desde dos modalidades de trabajo, una vinculada al trabajo rural de la cadena forestal y otra a una empresa de plataforma digital, en tanto formas emergentes del contexto laboral uruguayo.
Analysis of the current state and forecasts of the development of the residential real estate market of the Republic of Kazakhstan
Authors: Sikhimbayev M. R. , Srailova G. N. , Flek A. A. 
Published: July 2024

Purpose of the study – describe the state of the Kazakhstan residential real estate market, identify the features and trends of its development. The authors of the study pay special attention to the analysis of the main indicators characterizing the residential real estate market, as well as the processes taking place in the mortgage lending market. Methodology – the study was conducted using methods of economic and statistical analysis, graphic method, method of description and generalization. The research sources were offi cial statistical materials of the National Bank of Kazakhstan, analytical reviews of consulting companies and fi nancial organizations, the «Krisha.kz» real estate platform and the «Kn.kz» real estate information portal, scientifi c research by Kazakh and foreign authors, as well as materials of scientifi c and practical conferences. Originality / value of the study – the authors carried out a detailed analysis of the state and problems of the residential real estate market of the Republic of Kazakhstan in recent years and gave forecasts for its future development. Findings. According to the results of research and analysis of the current state of the Kazakh residential real estate market in recent years, the authors identifi ed problems and identifi ed current trends in the development of the housing market, as well as forecasts of its future development. The results of the scientifi c article can be useful for real estate agencies, industry experts, as well as the scientifi c community involved in studying the real estate market.
Dust in the (Solar) Wind: Investigations of Orbital Debris and Asteroid Evolution
Authors: Hartzell Christine 
Published: July 2024

The interaction of charged particles with the local plasma environment is of interest in a variety of space applications. This talk will focus on two specific applications: 1. the design of new technologies to detect orbital debris and 2. the evolution of asteroid surfaces. Small (sub-cm) orbital debris poses a serious hazard to functional spacecraft, but is very difficult detect (and impossible to track) using conventional technologies. Our simulations predict that many of these debris objects will produce solitons in the ionospheric plasma environment. We will present the characteristics of the debris that are predicted to produce solitons and the characteristics of the resulting solitons. Detection of debris-produced solitons may provide a new technique to monitor the highly uncertain sub-cm debris environment. Our second topic concerns the removal of small particles from the surfaces of asteroids. The regolith of many small asteroids is coarse compared to other solar system bodies like the Moon. It has been hypothesized that small regolith particles may be removed from asteroids due to the interaction of the charged particles with the local plasma environment. We will present predictions of the sizes of particles that can be lofted from the asteroid Bennu and the subsequent trajectories (including escape) of those particles. We will also show experimental observations of the electrostatic lofting of clumps of regolith particles. Electrostatic lofting, combined with solar radiation pressure, may be an active loss mechanism on asteroids.
Impact of hyperthermic intraperitoneal chemotherapy on gastric cancer survival: Peritoneal metastasis and cytology perspectives
Authors: Methasate Asada , Parakonthun Thammawat , Intralawan Thita , Nampoolsuksan Chawisa , Swangsri Jirawat 
Published: July 2024

BACKGROUND
Gastric cancer presenting with peritoneal metastasis is notably associated with diminished survival prospects. The use of cytoreductive surgery in conjunction with hyperthermic intraperitoneal chemotherapy (HIPEC) has been shown to increase survival rates in these patients. Despite these advancements, debates persist regarding the magnitude of survival improvement attributed to this treatment modality. The present investigation examined survival outcomes following HIPEC in individuals diagnosed with gastric cancer and peritoneal metastasis, and it took a comparative analysis of patients exhibiting positive and negative cytological findings.
AIM
To compare the impact of HIPEC on survival in gastric cancer patients with peritoneal metastasis and positive or negative cytology.
METHODS
Between April 2013 and March 2020, 84 patients with advanced gastric cancer treated at our institution were categorized into three cohorts: HIPEC (20 patients with peritoneal metastasis), cytology-positive (23 patients without peritoneal nodules but with positive wash cytology), and cytology-negative (41 patients with advanced gastric cancer, no peritoneal nodules, and negative wash cytology). The HIPEC cohort underwent gastrectomy with HIPEC, while the cytology-positive and cytology-negative groups received gastrectomy alone. The demographic, pathological, and survival data of the groups were compared.
RESULTS
The HIPEC cohort-predominantly younger females-exhibited relatively extended surgical durations and high blood loss. Nevertheless, the complication rates were consistent across all three groups. Median survival in the HIPEC group was 20.00 ± 4.89 months, with 1-year, 2-year, and 3-year overall survival rates of 73.90%, 28.70%, and 9.60%, respectively. These figures paralleled the survival rates of the cytology-positive group (52.20% at 1 year, 28.50% at 2 years, and 19.00% at 3 years). Notably, 47% of patients experienced peritoneal recurrence.
CONCLUSION
HIPEC may offer a modest improvement in short-term survival for patients with gastric cancer and peritoneal metastasis, mirroring the outcomes in cytology-positive patients. However, peritoneal recurrence remained high.
Parthenolide enhances the metronomic chemotherapy effect of cyclophosphamide in lung cancer by inhibiting the NF-kB signaling pathway
Authors: Cai Zheng , Gao Lang , Hu Kai , Wang Qi-Ming 
Published: July 2024

BACKGROUND
Parthenolide (PTL), a sesquiterpene lactone derived from the medicinal herb Chrysanthemum parthenium, exhibits various biological effects by targeting NF-kB, STAT3, and other pathways. It has emerged as a promising adjunct therapy for multiple malignancies.
AIM
To evaluate the in vitro and in vivo effect of PTL on cyclophosphamide (CTX) metronomic chemotherapy.
METHODS
The cytotoxicity of PTL and CTX on Lewis lung cancer cells (LLC cells) was assessed by measuring cell activity and apoptosis. The anti-tumor efficiency was evaluated using a tumor xenograft mice model, and the survival of mice and tumor volume were monitored. Additionally, the collected tumor tissues were analyzed for tumor microenvironment indicators and inflammatory factors.
RESULTS
In vitro , PTL demonstrated a synergistic effect with CTX in inhibiting the growth of LLC cells and promoting apoptosis. In vivo , metronomic chemotherapy combined with PTL and CTX improved the survival rate of tumor-bearing mice and reduced tumor growth rate. Furthermore, metronomic chemotherapy combined with PTL and CTX reduced NF-κB activation and improved the tumor immune microenvironment by decreasing tumor angiogenesis, reducing Transforming growth factor β, and α-SMA positive cells.
CONCLUSION
PTL is an efficient compound that enhances the metronomic chemotherapy effects of CTX both in vitro and in vivo , suggesting its potential as a supplementary therapeutic strategy in metronomic chemotherapy to improve the chemotherapy effects.
Predictive value of tumor-infiltrating lymphocytes for neoadjuvant therapy response in triple-negative breast cancer: A systematic review and meta-analysis
Authors: Sun Hai-Kuan , Jiang Wen-Long , Zhang Shi-Lei , Xu Peng-Cheng , Wei Li-Min , Liu Jiang-Bo 
Published: July 2024

BACKGROUND
The association between tumor-infiltrating lymphocyte (TIL) levels and the response to neoadjuvant therapy (NAT) in patients with triple-negative breast cancer (TNBC) remains unclear.
AIM
To investigate the predictive potential of TIL levels for the response to NAT in TNBC patients.
METHODS
A systematic search of the National Center for Biotechnology Information PubMed database was performed to collect relevant published literature prior to August 31, 2023. The correlation between TIL levels and the NAT pathologic complete response (pCR) in TNBC patients was assessed using a systematic review and meta-analysis. Subgroup analysis, sensitivity analysis, and publication bias analysis were also conducted.
RESULTS
A total of 32 studies were included in this meta-analysis. The overall meta-analysis results indicated that the pCR rate after NAT treatment in TNBC patients in the high TIL subgroup was significantly greater than that in patients in the low TIL subgroup (48.0% vs 27.7%) (risk ratio 2.01; 95% confidence interval 1.77-2.29; P < 0.001, I 2 = 56%). Subgroup analysis revealed that the between-study heterogeneity originated from differences in study design, TIL level cutoffs, and study populations. Publication bias could have existed in the included studies. The meta-analysis based on different NAT protocols revealed that all TNBC patients with high levels of TILs had a greater rate of pCR after NAT treatment in all protocols (all P ≤ 0.01), and there was no significant between-protocol difference in the statistics among the different NAT protocols (P = 0.29). Additionally, sensitivity analysis demonstrated that the overall results of the meta-analysis remained consistent when the included studies were individually excluded.
CONCLUSION
TILs can serve as a predictor of the response to NAT treatment in TNBC patients. TNBC patients with high levels of TILs exhibit a greater NAT pCR rate than those with low levels of TILs, and this predictive capability is consistent across different NAT regimens.