bluuebunny/crossref_metadata_2025_split huggingface dataset:
Putting QR codes to the test
Authors: Lo Leo , Coleman Jason , Theiss Danielle 
Published: November 2013

Purpose
– The purpose of this paper is to gain insight into patrons' preferences for quick response code (QR code) design as well as data about their potential benefits.

Design/methodology/approach
– A survey was used to learn whether patrons find it easy to use a QR code, to gather patrons' opinions about several possible library uses for QR codes, and to solicit additional ideas for using QR codes in libraries. A small-scale pilot project was implemented to learn whether the Libraries' patrons would make use of QR codes. To augment the data gained from the first two studies, five focus groups were facilitated.

Findings
– The authors found that patrons generally find QR codes easy to use and would welcome a variety of library services on their mobile devices.

Research limitations/implications
– Further studies on a variety of mobile devices would be a useful way to gain more insight into how libraries can take advantage of mobile communication to provide services to patrons.

Originality/value
– This paper would appeal to academic libraries considering implementing QR codes projects as there are only a very limited number of studies on library users' preferences of QR codes.
Data sharing and its implications for academic libraries
Authors: Kim Jeonghyun 
Published: November 2013

Purpose
– As an important aspect of the scientific process, research data sharing is the practice of making data used for scholarly research publicly available for use by other researchers. This paper seeks to provide a more comprehensive understanding of the data-sharing challenges and opportunities posed by the data deluge in academics. An attempt is made to discuss implications for the changing role and functioning of academic libraries.

Design/methodology/approach
– An extensive review of literature on current trends and the impact of data sharing is performed.

Findings
– The context in which the increasing demands for data sharing have arisen is presented. Some of the practices, trends, and issues central to data sharing among academics are presented. Emerging implications for academic libraries that are expected to provide a data service are discussed.

Originality/value
– An insightful review and synthesis of context, issues, and trends in data sharing will help academic libraries to plan and develop programs and policies for their data services.
Shaping a profession?
Authors: Kallberg Maria 
Published: November 2013

Purpose
– In order to work more efficiently with internal and external processes, public organisations are working with reorganisation and centralisation of documentation practices as part of a holistic approach to manage and control information flows. The registry function has a long tradition built on legislative requirements concerning registration of official documents in order to fulfil the citizens' rights to access information. The purpose of this paper is to demonstrate challenges related to recordkeeping legislative awareness within a public organisation and how a changing context may impact on the registrars' status.

Design/methodology/approach
– The data presented and analysed are based on a longitudinal case study of a centralised registry function project undertaken by a Swedish local government body (a municipality). Interviews have been used as the primary data collection method.

Findings
– The findings identify challenges that result from a lack of recordkeeping skills and recordkeeping legislative awareness that needs to be solved in order to reach a successful implementation. Even though the registry function is identified as strategically important, the registrars have not reached the status “expert”. Changing context does not necessarily lead to a change in status. It is a more complex process, which includes attitudes, knowledge and skills.

Research limitations/implications
– The research is limited by being a case study in a single organisation in the Swedish public sector context.

Practical implications
– The findings could be useful for public organisations that intend to reorganise and centralise documentation practices. Furthermore, the findings contribute to record keeping practitioners and also to stakeholders within public organisations.

Originality/value
– Registrars as an occupational group in Sweden have not been the focus of any extensive academic research. In view of its new strategic importance the registry function has benefitted from organisational restructuring; research is needed on registrars as a possible future “records management profession”, which does not currently exist in Sweden.
Enterprise Content Management and the Records Continuum Model as strategies for long-term preservation of digital information
Authors: Svärd Proscovia 
Published: November 2013

Purpose–The purpose of the paper is to establish whether Enterprise Content Management (ECM) and Records Continuum Model (RCM) frameworks could be used to mitigate long-term preservation challenges.Design/methodology/approach–Qualitative research was undertaken using two case studies and interviews were conducted with the different categories of the municipal personnel to solicit answers to the research questions. The questions were designed using the lens of the RCM and its four dimensions that cover the creation, capture, organization and pluralization of records and prescribed factors of ECM which include business process management, enterprise architecture, collaboration, system integration, re-purposing of information, change management, knowledge management and the life cycle management of information. Not all the ECM factors are dealt with in this paper: the remainder have been dealt with in the author's earlier works.Findings–Challenges of long-term preservation of information still persist despite the enormous research that has been generated over the years. The municipalities that were subjects of this research are still grappling with issues of lack of long-term information management policies, enterprise architecture, disparate information systems, collaboration and system integration. This is likely to work against the investments that are being ploughed into e-Government developments should the municipalities fail to espouse strong information and records management regimes. Embracing the ECM prescribed factors and the RCM thinking might mitigate these challenges.Originality/value–The author's licentiate research proved that there was no discourse between records managers/archivists and ECM proponents. Therefore, the originality of this article lies in the application of the two frameworks of ECM and RCM. The findings confirmed that even within the records management framework the municipalities were addressing factors similar to ECM prescribed factors. Embracing both the RCM model and the ECM prescribed factors might mitigate the challenges of long-term preservation and hence the re-use of information and enhancement of the societal memory.
Design of Mini‐barcode for Catfishes for assessment of archival biodiversity
Authors: Bhattacharjee Maloyjo J. , Ghosh Sankar K. 
Published: November 2013

AbstractRecovery of DNA barcode sequences is often challenging from the archived specimens. However, short fragments of DNA may be recovered, which would significantly improve many unresolved taxonomic conflicts. Here, we designed a mini‐barcode for catfishes comprising several species and many cryptic taxa. We analysed a data set of 3048 publicly available COI barcode sequences representing 547 worldwide catfish species and performed 152 628 interspecies comparisons. A significantly more positively correlated interspecies distance was detected with transversion (0.78, P < 0.001) than with transition (0.70, P < 0.001). This suggested that transversions were better diagnostics for species identification. In the aligned data set, two transversion‐rich fragments (53 bp and 119 bp) were identified. Transition/transversion bias value was 1.04 in 53‐bp fragment, 1.23 in 119‐bp fragment and 1.50 in full‐length barcode. The interspecies distance with full‐length barcode was 0.212 ± 0.037, while that with 53‐bp and 119‐bp fragments was 0.325 ± 0.039 and 0.218 ± 0.045, respectively. Survey of 53‐bp fragment showed a possibility of only 1144 barcodes, while that of 119‐bp fragment showed >4 million barcodes. Thus, the 119‐bp fragment is a viable mini‐barcode for catfishes comprising >3000 extant species. Experiment with 82 archived catfishes showed successful recovery of this mini‐barcode using the designed primer. The mini‐barcode sequences showed species‐specific similarity in the range of 98‐100% with the global database. Therefore, survey of a transversion‐rich fragment within the full‐length barcode would be an ideal approach of mini‐barcode design for biodiversity assessment.
Prognosis of esophageal squamous cell carcinoma patients with preoperative radiotherapy: Comparison of different cancer staging systems
Authors: Wang Qifeng , Zhang Wencheng , Liu Xiao , Zhang Xun , He Jie , Feng Qinfu , Zhou Zongmei , Wang Lvhua , Yin Weibo , Xiao Zefen 
Published: November 2013

AbstractBackgroundThe 7th edition American Joint Committee on Cancer tumor‐node‐metastasis (AJCC TNM) staging system was published in 2010. Here we evaluate its predictive ability and compare the 6th and 7th editions of the AJCC TNM staging systems in esophageal squamous cell cancer (ESCC) with preoperative radiotherapy.MethodsA total of 296 esophageal squamous cell carcinoma patients receiving preoperative radiotherapy between 1980 and 2007 were included. Patients were staged using the 6th and 7th edition staging systems. Survival analyses were performed using Cox regression models. The homogeneity, discriminatory ability, and monotonicity of gradients of the two staging systems were compared using linear trend χ2, likelihood ratio statistics, and Akaike information criterion calculation.ResultsThe overall five‐year survival rate for the entire cohort was 27.1%. Female gender, length, “T,” and “N,” classifications according to the 7th edition staging system were the prognostic factors in univariate analyses. However, tumor histological grade and cancer location did not significantly influence patient survival. The 7th edition staging system has the highest linear trend χ2 and likelihood ratio χ2 scores. Compared to the 6th edition, the 7th edition staging system also has a smaller Akaike information criterion value, which represents the optimum prognostic stratification.ConclusionsThe strength of the 7th edition AJCC TNM staging system lies in the new descriptors for “T” and “N” classifications. However, we did not find cancer location to be a significant prognostic factor in our cohort. Overall, the 7th edition AJCC TNM staging system performed better than the previous edition.
Neoadjuvant intra‐arterial chemotherapy in advanced laryngeal and hypopharyngeal cancer
Authors: Gupta Pankaj , Bhalla Ashu Seith , Thulkar Sanjay , Kumar Atin , Mohanti Bidhu Kalyan , Thakar Alok , Sharma Atul , Vishnubhatla Sreenivas 
Published: November 2013

AbstractAimTo investigate whether neoadjuvant intra‐arterial chemotherapy down‐stages the tumors and predicts ultimate outcome in patients with advanced laryngeal and hypopharyngeal cancer.MethodsFifteen patients with stage III and IV cancers received two cycles of intra‐arterial cisplatin (40 mg/m2) at days 1 and 15, infused super‐selectively into superior thyroid artery. Interim evaluation using RECIST 1.1 and volumetry was done in all patients at day 25. Subsequently, the patients received concurrent chemoradiotherapy or surgery with radiotherapy. Final evaluation was done in 10 patients.ResultsAt interim evaluation, five patients qualified as responders. Partial response, stable disease and progressive disease rates were 40, 33 and 27%, respectively. At final evaluation, complete response was noted in all patients.ConclusionsAt interim evaluation, the response rates were lower compared to intravenous neoadjuvant chemotherapy and response to intra‐arterial chemotherapy did not predict the ultimate outcome. Thus neoadjuvant intra‐arterial chemotherapy offers no advantage over concurrent chemoradiotherapy.
Pretreatment maximum standardized uptake value on 18F‐fluorodeoxyglucose positron emission tomography is a predictor of outcome for stage I non‐small cell lung cancer after stereotactic body radiotherapy
Authors: Tanaka Hidekazu , Hayashi Shinya , Hoshi Hiroaki 
Published: November 2013

AbstractAimsStereotactic body radiotherapy (SBRT) is commonly considered an important treatment option for patients with stage I non‐small cell lung cancer (NSCLC) who have contraindications for surgery or refuse surgery. Many studies have reported that the maximum standardized uptake value (SUVmax) on 18F‐fluorodeoxyglucose positron emission tomography (FDG‐PET) of the primary tumor has prognostic value for resected NSCLC. The purpose of this study was to determine whether SUVmax is a predictor of disease‐free survival (DFS) in patients with stage I NSCLC after SBRT.MethodsIn all patients, the diagnosis was pathologically or cytologically confirmed. The prescription dose was 48 Gy in four fractions at the isocenter. FDG‐PET was performed before SBRT.ResultsTwenty‐nine patients were enrolled in this study. The median follow‐up period was 14 months (range, 2–56 months). Regional lymph node metastasis and distant metastasis were observed in 5 (17%) and 2 (7%), respectively. The median SUVmax was 5.6 (range, 2.2–22.0). DFS at 2 years was significantly different between the low SUVmax (<8.0) and high SUVmax (≥8.0) groups (85 versus 17%). In univariate analysis, SUVmax and gross tumor volume were significantly correlated with DFS. Multivariate analysis included variables with P‐values <0.20 and showed that only SUVmax was significantly correlated with DFS.ConclusionPretreatment SUVmax on FDG‐PET predicted the DFS in patients with stage I NSCLC after SBRT.
Metabolic atrophy and 3‐T 1H‐magnetic resonance spectroscopy correlation after radiation therapy for prostate cancer
Authors: Panebianco Valeria , Barchetti Flavio , Musio Daniela , Forte Valerio , Pace Alberto , De Felice Francesca , Barchetti Giovanni , Tombolini Vincenzo , Catalano Carlo 
Published: November 2013

ObjectiveTo correlate 3‐T magnetic resonance spectroscopic imaging (MRSI) with prostate‐specific antigen (PSA) levels in patients with prostate cancer treated with external beam radiation therapy to assess the potential advantages of MRSI.Materials and MethodsA total of 50 patients (age range 65–83 years) underwent PSA and MRSI surveillance before and at 3, 6, 12, 18 and 24 months after radiotherapy.ResultsOf the 50 patients examined, 13 patients completely responded to therapy showing metabolic atrophy (MA), defined as a choline‐plus‐creatine/citrate (CC/C) ratio <0.2, at 3 months; in this group none had biochemical relapse (PSA nadir + 2 ng/mL) by the end of the follow‐up.Of the 50 patients, 35 showed a partial response to therapy (CC/C ratio between 0.2 and 0.8) at 3 and 6 months and, of these 35 patients, 30 reached MA at 12 months, while five developed a recurrence (CC/C ratio >0.8).Three of those patients with recurrence had a biochemical relapse at 18 months and the other two at 24 months.Two of the 50 patients did not respond to the treatment, showing persistent disease from the 3rd month (CC/C ratio >0.8); one patient had biochemical relapse at 6 and the other at 12 months.ConclusionsMRSI was shown to have a greater potential than PSA level in monitoring patients after radiotherapy, because it anticipates PSA nadir, and biochemical relapse in particular.
Alveolar ridge preservation techniques: a systematic review and meta‐analysis of histological and histomorphometrical data
Authors: De Risi Valeria , Clementini Marco , Vittorini Gianluca , Mannocci Alice , De Sanctis Massimo 
Published: November 2013

AbstractAimThe aim of this article was to systematically review histological and histomorphometrical data from literature that provide information regarding the effect of alveolar ridge preservation procedures on healing after tooth extraction in humans.Materials and methodsThe MEDLINE‐PubMed and the Cochrane CENTRAL databases were searched up to September 2012; 38 papers were selected from 646 founded. A meta‐analysis was performed regarding the variations in the mean percentage of Bone, Connective Tissue and Residual Graft Material between three different types of Procedures.ResultsThe highest value regarding bone percentages is produced at 3 months by Procedures with Allografts (54.4%), while the lowest is obtained, at 5 months, by those using Xenografts (23.6%). Referring to connective tissue, the highest and lowest values are shown at 7 months, with Allografts (67%) and Alloplasts (27.1%), respectively. Regarding residual graft material, the lowest rates are displayed by Procedures with Allografts (12.4–21.11%), while those using Xenografts and Alloplasts showed the best results at 7 months (37.14 and 37.23%). No statistical difference was found.ConclusionsWith the limitations due to the features of the selected papers, no major histological and histomorphometrical differences arose among different procedures or when compared to spontaneous healing. Thus, it might be argued that in preserved sites it is unnecessary to wait over 3 to 4 months prior to implant insertion.
Glucose control in non‐critically ill inpatients with diabetes: towards closed‐loop
Authors: Thabit H. , Hovorka R. 
Published: November 2013

AbstractInpatient glycaemic control remains an important issue due to the increasing number of patients with diabetes admitted to hospital. Morbidity and mortality in hospital are associated with poor glucose control, and cost of hospitalization is higher compared to non‐diabetes patients. Guidelines for inpatient glycaemic control in the non‐critical care setting have been published. Current recommendations include basal‐bolus insulin therapy, regular glucose monitoring, as well as enhancing healthcare provider's role and knowledge. In spite of growing focus, implementation in practice is limited, mainly due to increasing workload burden on staff and fear of hypoglycaemia. Advances in healthcare technology may contribute to an improvement of inpatient diabetes care. Integration of glucose measurements with healthcare records and computerized glycaemic control protocols are currently being used in some institutions. Recent interests in continuous glucose monitoring have led to studies assessing its utilization in inpatients. Automation of glucose monitoring and insulin delivery may provide a safe and efficacious tool for hospital staff to manage inpatient hyperglycaemia, whilst reducing staff workload. This review summarizes the evidence on current approaches to managing inpatient glycaemic control; its utility and limitations. We conclude by discussing the evidence from feasibility studies to date, on the potential use of closed loop in the non‐critical care setting and its implication for future studies.
Interferon‐induced programmed death‐ligand 1 (PD‐L1/B7‐H1) expression increases on human acute myeloid leukemia blast cells during treatment
Authors: Krönig Holger , Kremmler Lukas , Haller Bernhard , Englert Carsten , Peschel Christian , Andreesen Reinhard , Blank Christian U. 
Published: November 2013

AbstractIntroductionWhile current treatment for acute myeloid leukemia is characterized by high response rates, patients' long‐term outcome is still disappointing, due to frequent relapse and ineligibility of the often elderly patients for stem cell transplantation approaches. Considerable efforts have, thus, been made to incorporate immunotherapeutic approaches in the acute myeloid leukemia (AML) consolidation, with so far disappointing clinical benefit. The B7 family ligand programmed‐death receptor‐ligand 1 (PD‐L1, B7‐H1, CD274) has been recently described (with conflicting results) to be expressed on AML blast cells, and interaction with its receptor on T cells, programmed death receptor‐1 (PD‐1, CD279), has been shown to suppress T‐cell functions and to allow survival of dormant AML cells in animal models.Design and MethodsIn this work, we analyzed freshly isolated myeloid precursor cells from healthy donors and from AML patients for PD‐L1 expression with or without interferon‐γ exposure at different time points during their treatment.ResultsWhile without IFN exposure, only minor differences were observed, we found IFN‐γ‐induced PD‐L1 expression most prominent after initial treatment and independent of treatment outcome.ConclusionsOur observations support the recently suggested PD‐L1‐mediated adaptive immune resistance and argue for a targeting of the PD‐L1/PD‐1 pathway during the consolidation phase of AML treatment.
Identifying global zoogeographical regions: lessons from Wallace
Authors: Rueda Marta , Rodríguez Miguel Á. , Hawkins Bradford A. 
Published: November 2013

AbstractAimWhen dividing the world into zoogeographical regions, Alfred Russel Wallace stipulated a set of criteria by which regions should be determined, foremost the use of generic rather than species distributions. Yet, recent updates of Wallace's scheme have not followed his reasoning, probably explaining in part the discrepancies found. Using a recently developed quantitative method, we evaluated the world's zoogeographical regions following his criteria as closely as possible.LocationGlobal.MethodsWe subjected presence–absence data from range maps of birds, mammals and amphibians to an innovative clustering algorithm, affinity propagation. We used genera as our taxonomic rank, although species and familial ranks were also assessed, to evaluate how divergence from Wallace's criteria influences the results. We also accepted Wallace's argument that bats and migratory birds should be excluded (although he was contradictory about the birds) and devised a procedure to determine the optimal number of regions to eliminate subjectivity in delimiting the number of regions.ResultsRegions attained using genera (eight for mammals and birds and six for amphibians) strongly coincided with the regions proposed by Wallace. The regions for amphibians were nearly identical to Wallace's scheme, whereas we obtained two new ‘regions’ for mammals and two for birds that largely coincide with Wallace's subregions. As argued by Wallace, there are strong reasons not to consider these as being equivalent to the six main regions. Species distributions generated many small regions related to contemporary climate and vegetation patterns, whereas at the familial rank regions were very broad. The differences between our generic maps and Wallace's all involve areas which he identified as being uncertain in his regionalization.Main conclusionsDespite more than 135 years of additional knowledge of distributions, the shuffling of generic concepts, and the development of computers and complex analytical techniques, Wallace's zoogeographical regions appear to be no less valid than they were when he proposed them. Recent studies re‐evaluating Wallace's scheme should not be considered updates as such because they have not followed Wallace's reasoning, and all computer‐based analyses, including this one, are subject to the vagaries of the particular methods used.