bluuebunny/crossref_metadata_2025_split huggingface dataset:
Robot-assisted percutaneous cannulated screw fixation in the treatment of slipped capital femoral epiphysis
Authors: Xu Yunfeng , Fu Gang , Feng Chao , Huang Lin , Ma Yuan , Zhang Yucheng , Zhou Yuan , Luo Xiao , Lu Ming , Yang Jie , Wang Yukun , Lv Xuemin , Jiang Xieyuan , Yang Zheng 
Published: February 2025

Purpose: To investigate robot-assisted percutaneous cannulated screw fixation for treating slipped capital femoral epiphysis, including acute, chronic, and acute-on-chronic slips. Our study included all stable and unstable slips. Methods: Thirty-one children with unilateral SCFE were treated from October 2019 to October 2021. All 31 patients were followed up for 12–36 months, with an average follow-up time of 24.56 ± 6.73 months. The femoral epiphysis was fixed with a percutaneous cannulated screw assisted by a surgical robot. Results: All 31 femoral head epiphyses underwent successful fixation in one attempt. The average operation time and bleeding were 98.25 ± 15.13 min and 21.65 ± 11.25 ml, respectively. The average distance between the actual and planned entry points was 1.13 ± 0.58 mm and 0.91 ± 0.72 mm in the anteroposterior (AP) and lateral views, respectively. The actual insertion trajectory deviated from the planned position by 3.61 ± 1.34° and 2.33 ± 1.32° in the AP and lateral views, respectively. The average fluoroscopy time was 6.56 ± 3.23 times per screw. The Non-Arthritic Hip Score improved from 28.53 ± 9.17 preoperatively to 67.34 ± 6.21 at the last follow-up ( P < 0.05), and the Harris hip score improved from 46.47 ± 15.34 to 89.63 ± 7.52 ( P < 0.05). The wounds healed without avascular necrosis or chondrolysis of the femoral head. Conclusion: Robot-assisted percutaneous cannulated screw fixation is effective for treating pediatric SCFE. Screw fixation was accurate and safe, and clinical outcomes were satisfactory. Level of Evidence: Level 4, Case Series.
Availability of Open Dynamic Glycemic Data in the Field of Diabetes Research: A Scoping Review
Authors: Del Giudice Libera Lucia , Piersanti Agnese , Göbl Christian , Burattini Laura , Tura Andrea , Morettini Micaela 
Published: February 2025

Background: Poor data availability and accessibility characterizing some research areas in biomedicine are still limiting potentialities for increasing knowledge and boosting technological advancement. This phenomenon also characterizes the field of diabetes research, in which glycemic data may serve as a basis for different applications. To overcome this limitation, this review aims to provide a comprehensive analysis of the publicly available data sets related to dynamic glycemic data. Methods: Search was performed in four different sources, namely scientific journals, Google, a comprehensive registry of clinical trials and two electronic databases. Retrieved data sets were analyzed in terms of their main characteristics and on the typology of data provided. Results: Twenty-five data sets were identified including data from challenge tests (5 of 25) or data from Continuous Glucose Monitoring (CGM, 20 of 25). As for the data sets including challenge tests, all of them were freely downloadable; most of them (80%) related only to oral glucose tolerance test (OGTT) with standard duration (2 h), but varying for timing and number of collected blood samples, and variables collected in addition to glucose levels (with insulin levels being the most common); the remaining 20% of them also included intravenous glucose tolerance test (IVGTT) data. As for the data sets related to CGM, 7 of 20 were freely downloadable, whereas the remaining 13 were downloadable upon completion of a request form. Conclusions: This review provided an overview of the readily usable data sets, thus representing a step forward in fostering data access in diabetes field.
Results of urethral reconstruction in neglected urethral foreign bodies with associated urethral strictures
Authors: Trivedi Sameer , Goel Nitin , Pal Harish , Reddy Koti Sridhar , M Rinaldo , Nayak Pradeep , Singh Yashasvi , Kumar Ujwal 
Published: February 2025

Objective: Urethral foreign bodies with associated urethral strictures are unusual entities. Although few case studies have reported the management of urethral foreign bodies, the management of neglected foreign bodies with resultant urethral strictures has not been addressed in the literature. Materials and Methods: A retrospective review of 15 patients diagnosed with strictures and associated urethral foreign bodies was performed for collection of data, viz., demographic and clinicopathological factors; details of urethral reconstruction procedures; perioperative and postoperative events; and follow-up data. Results: Underlying aetiology was self-insertion for sexual gratification in nine patients (metallic safety pins – 3, wooden splinters – 2, electric cables – 2, and plastic rods in two patients), gunshot injuries with embedded pellets in 4, and iatrogenic foreign bodies in two patients. Three patients had complete urethral obstruction, six had bulbar strictures, four had penile urethral strictures, and two had pan urethral strictures. Seven strictures were managed by primary end-to-end anastomosis, three by augmented roof-strip anastomosis using oral mucosal grafts, while the remaining five patients required augmentation urethroplasty using oral mucosal grafts. The overall success rate of urethral reconstruction was 93.3%. Conclusion: Neglected urethral foreign bodies with associated urethral strictures are uncommon. Surgical management, although challenging owing to an unhealthy local milieu, has satisfactory outcomes. Level of Evidence: Not applicable.
Advocating Submission of Case Reports in Family Medicine: An Analysis of Case Report Submissions in Journals Related to Family Medicine
Authors: Wattanapisit Apichai , Sirirak Kosin , Wattanapisit Sanhapan , Jenn Ng Chirk , Hai Teo Chin , Wiwatkunupakarn Nutchar , Aramrat Piyachon , Angkurawaranon Chaisiri 
Published: February 2025

Introduction: Family medicine embraces a wide range of principles. Identifying appropriate journals for publishing family medicine case reports can be challenging for authors. This study aims to identify journals related to family medicine that publish case reports and summarize the requirements of case report submissions. Methods: Journals related to family medicine were identified from the subject categories: “family practice” in Scopus and “primary health care” in Web of Science. The author’s instructions on the journal websites regarding the criteria for case report submissions were reviewed, and the specific requirements for case reports of each journal were recorded. Journals were excluded if family medicine was not the main aim and scope. Results: Among the 80 journals focused on family medicine, 30 (37.5%) were found to accept submissions of case reports. These reports were classified into various article types, such as case reports, patient studies, clinical case studies. The length of the main text varied between 400 and 3000 words, and some journals did not mandate an abstract. However, for those that did, abstracts typically ranged from 50 to 300 words. The number of references cited ranged from 5 to 30. Conclusions: Less than half of the journals in the family medicine field accept case report submissions. It is advisable for authors to choose their target journal early in the preparation process, as each journal typically provides specific submission guidelines and instructions.
The Association of Modic Changes and Disc-Endplate-Bone Marrow Complex Classification in Patients With Cervical Degenerative Disc Disease
Authors: Jagadish T , Murugan Chandhan , Ramachandran Karthik , Thippeswamy Pushpa Bhari , Anand K S Sri Vijay , Kanna Rishi Mugesh , Shetty Ajoy Prasad , Rajasekaran Shanmuganathan 
Published: February 2025

Study design Observational cohort study. Objective To assess the association of Modic changes and DEBC classification in patients with cervical degenerative disc disease. Methods The study includes 2 groups, neck pain patients presenting to the out-patient services (neck pain group) (n = 301) and polytrauma patients without cervical spine injury or a history of neck pain, who underwent whole spine MRI (control group) (n = 200). Degenerative changes in the MRI were classified according to the Modic changes (MC) and DEBC classification. Modifiers including End-Plate (EP) erosion and herniation (H+) presence were documented. Results 3612 EPs of 301 patients with neck pain and 2400 EPs of 200 controls were assessed. The incidence of MC and DEBC in the neck pain group was 20.93% and in the control group, it was 12%, ( P < 0.05). In the neck pain group with DEBC changes, the distribution was Type A-6.51%; Type B-20.71%; Type C-71.6%; and Type D - 1.18%, while in the controls the distribution was Type A-10.29%, Type B-29.41%, Type C-54.41%, and Type D - 5.88%, The co-occurrence of H+ with DEBC in cases and controls was 13.95% vs 5.5% ( P < 0.005). The odds ratio for the need for surgery was highest (OR: 6.8) when H+ and DEBC change co-occurred. Conclusion Our study highlights that patients with DEBC changes and disc herniation were more likely to experience neck pain and require surgical intervention, indicating the reliability and clinical significance of the DEBC classification in degenerative cervical spine patients.
Adiposity and domain-specific stroke recovery: A Mendelian randomization study
Authors: Wang Mengmeng , Daghlas Iyas , Aldridge Chad M , Zhang Zhizhong , Ren Yi 
Published: February 2025

Introduction: While adiposity is an established risk factor for incident ischemic stroke, its influence on functional recovery after stroke is uncertain. We leveraged Mendelian randomization (MR) to examine the causal effects of body mass index (BMI) and waist-to-hip ratio (WHR) on post-stroke motor, cognitive, and global recovery. Materials and methods: Genetic proxies for BMI and WHR were obtained from a genome-wide association study (GWAS) meta-analysis of the GIANT consortium and the UK Biobank ( n = 806,834). The primary outcomes were longitudinal trajectories of three National Institutes of Health Stroke Scale (NIHSS) measures assessed over a 2-year period: motor function subscores, cognitive performance subscores, and total NIHSS scores (as a measure of global recovery). Genetic associations with these stroke recovery outcomes were obtained from a GWAS conducted within the VISP trial of mild ischemic stroke ( n = 1270). MR effects were estimated using the inverse-variance weighted method. Results: A 1-standard deviation (SD) increase (~4.8 kg/m2) in genetically predicted BMI associated with lower odds of post-stroke motor improvement (OR = 0.37, 95% CI = 0.19-0.72; p = 0.003). Similarly, a genetically predicted increase in BMI was associated with worse cognitive (β = −0.12, 95% CI = −0.21, −0.03; p = 0.009) and global recovery (β = −0.36, 95% CI = −0.59, −0.13; p = 0.002). Associations between genetically predicted WHR and post-stroke recovery were directionally concordant but were not statistically significant ( p > 0.05). Discussions and conclusions: Human genetic evidence suggests that elevated adiposity negatively impacts multiple post-stroke outcomes, including motor function, cognition, and overall recovery. The biological pathways underlying these associations warrant further investigation.
Outcomes of arteriovenous malformation patients with multiple versus single feeders: A multicenter retrospective study with propensity-score matching
Authors: Musmar Basel , Adeeb Nimer , Abdalrazeq Hammam , Roy Joanna M , Tjoumakaris Stavropoula I , Salim Hamza Adel , Kondziolka Douglas , Sheehan Jason , Ogilvy Christopher S , Riina Howard , Kandregula Sandeep , Dmytriw Adam A , El Naamani Kareem , Abdelsalam Ahmed , Ironside Natasha , Kumbhare Deepak , Ataoglu Cagdas , Essibayi Muhammed Amir , Keles Abdullah , Muram Sandeep , Sconzo Daniel , Rezai Arwin , Alwakaa Omar , Tos Salem M , Erginoglu Ufuk , Pöppe Johannes , Sen Rajeev D , Griessenauer Christoph J , Burkhardt Jan-Karl , Starke Robert M , Baskaya Mustafa K , Sekhar Laligam N , Levitt Michael R , Altschul David J , McAvoy Malia , Aslan Assala , Abushehab Abdallah , Swaid Christian , Abla Adib A , Sizdahkhani Saman , Koduri Sravanthi , Atallah Elias , Karadimas Spyridon , Gooch M Reid , Rosenwasser Robert H , Stapleton Christopher , Koch Matthew , Srinivasan Visish M , Chen Peng R , Blackburn Spiros , Cochran Joseph , Choudhri Omar , Pukenas Bryan , Orbach Darren , Smith Edward , Mosimann Pascal J , Alaraj Ali , Aziz-Sultan Mohammad A , Patel Aman B , Cuellar Hugo H , Lawton Michael , Guthikonda Bharat , Morcos Jacques , Jabbour Pascal 
Published: February 2025

Introduction: The impact of multiple feeding arteries on clinical outcomes of cerebral arteriovenous malformations (AVMs) is not well understood. This study aims to compare outcomes between AVMs with multiple versus single feeding arteries. Patients and Methods: Data from the Multicenter International Study for Treatment of Brain AVMs (MISTA) consortium were analyzed. Propensity score matching (PSM) was used to balance cohorts. Subgroup analysis was conducted for ruptured and unruptured AVMs and different treatment options, and multivariable logistic regression was applied to assess the impact of feeding artery origin. Results: Among 953 patients, 661(69.4%) had multiple feeding arteries, and 292 (30.6%) had a single feeding artery. After PSM, which included 422 matched patients (211 in each group), the differences in obliteration rates (68.7% vs 74.8%, OR 0.73, 95% CI: 0.48–1.12, p = 0.16) and symptomatic complications (15.6% vs 11.8%, OR 1.37, 95% CI: 0.78–2.41, p = 0.25) were not significant. Subgroup analysis comparing ruptured and unruptured AVMs and different treatment options showed no significant differences across all subgroups. Multivariable analysis identified PICA feeders as significantly associated with increased odds of all complications (OR 7.33, 95% CI: 2.14–25.1, p = 0.002). Discussion and Conclusion: AVMs with a single feeding artery were more likely to present with rupture, but no significant differences in obliteration rates or complications were observed between the groups after PSM. These findings suggest that while the number of feeding arteries may influence the initial presentation, it does not appear to impact overall treatment success or patient prognosis. Further prospective studies are needed to confirm these findings.
Safety and efficacy of travoprost intracameral implant administered in combination with cataract surgery
Authors: Singh Inder Paul , Voskanyan Lilit A. , Barber Kevin M. , Burden James H. , Connolly LeAnne , Katz L. Jay , Usner Dale W. , Kothe Angela C. , Navratil Tomas 
Published: February 2025

Background: The travoprost intracameral implant and cataract surgery both lower intraocular pressure (IOP). Objectives: We evaluated the safety and IOP-lowering effect at 3 months following administration of travoprost intracameral implant in combination with cataract surgery. Design: Prospective, 12-month, open-label, single-arm trial. Methods: We enrolled patients with age-related cataracts and open-angle glaucoma or ocular hypertension in the same eye. At baseline, patients were required to have an unmedicated mean diurnal IOP (average of 8:00 am, 10:00 am, and 4:00 pm IOPs) of 24 mmHg or greater, and an IOP of 36 mmHg or less at each of these three timepoints. On the day of the combined procedure (day 1), patients who had uncomplicated phacoemulsification cataract surgery received a travoprost intracameral implant. Follow-up evaluations occurred on day 2–3, week 2, week 6, and month 3 visits. Results: Sixty patients had uncomplicated cataract surgery and received a travoprost intracameral implant. There were no serious adverse events. Study eye adverse events were reported in 8.3% of patients. The most frequently reported adverse event was dry eye (6.7%). At month 3, the mean diurnal IOP change from baseline was −10.6 mmHg (95% confidence interval: −11.2, −9.9; p < 0.0001) from an unmedicated baseline mean diurnal IOP of 25.2 mmHg. In addition, at month 3, 97% of eyes had a 20% or greater mean diurnal IOP reduction from baseline, and 91.0% of eyes had a mean diurnal IOP of 18 mmHg or less. Conclusion: Administration of a travoprost intracameral implant combined with routine cataract surgery was safe. The sizable −10.6 mmHg IOP change from baseline at month 3 was both statistically significant and clinically relevant. Trial registration: NCT06061718, Travoprost Intraocular Implant in Conjunction with Cataract Surgery, https://clinicaltrials.gov/study/NCT06061718 .
Unsupervised Assessment of Frailty Status Using Wearable Sensors: A Feasibility Study among Community-Dwelling Older Adults
Authors: Giggins Oonagh Mary , Vavasour Grainne , Doyle Julie 
Published: February 2025

Objectives: This study examined whether community-dwelling older adults can independently capture wearable sensor data that can be used to classify frailty status. Methods: Fifty-one older adults (age 77.5 ± 8.4 years, height 163.6 77.5 ± 8.4, weight 72.0 ± 13.5 kg, female 76%) took part in this investigation. Participants independently captured physical activity and physical function data at home using a smartwatch and a research-grade inertial sensor system for 48-hours. Machine learning classifiers were used to determine whether the data obtained can discriminate between frailty levels. Results: Models incorporating variables from both the smartwatch and inertial sensor system were successful in the prediction of frailty status. Discussion: This study has demonstrated the ability of older adults to collect data which can be used to indicate their frailty risk. This may enable earlier intervention and lessen the impact of frailty on the individual and society as a whole.
The serial mediation effect of perceived quality and customer satisfaction on the relationship between trust and repurchase intention: a research on private health insurance owners
Authors: Gün İbrahim , Söyük Selma 
Published: February 2025

Abstract

Background
This study examined the serial mediating roles of perceived quality and customer satisfaction in the relationship between trust and repurchase intentions among private health insurance owners.

Methods
This cross-sectional study included 525 private health insurance owners. The data were collected between 15.12.2023 and 15.03.2024, and SPSS AMOS was used to analyze the direct and indirect estimates. The study utilized structural equation modeling (SEM) to examine the relationships among the constructs. The proposed model was tested using maximum likelihood estimation. Model fit indices and statistical significance levels were reported to ensure the robustness of the findings. Using an online survey, the participants completed self-reported measures of perceived quality, customer satisfaction, trust, and repurchase intention.

Results
Trust significantly affected perceived quality, customer satisfaction and repurchase intention. Furthermore, perceived quality acted as a mediator in the relationship between trust and customer satisfaction. Additionally, customer satisfaction played a partial mediating role in the relationship between trust and repurchase intention. Both perceived quality and customer satisfaction play a serial mediating role in the relationship between trust and repurchase intention.

Conclusions
This study highlighted the significance of perceived quality and customer satisfaction in the relationship between trust and repurchase intention. Private health insurance agencies both alleviate the burden on public health services and operate as profit-driven entities. Considering their indirect benefits to healthcare services, maintaining existing customer portfolios and acquiring new customers are important for both the health system and the profitability of insurance businesses.
Engagement of health and social care employers in professional regulatory fitness to practise – missed regulatory and organisational opportunities?
Authors: Wallace Louise M. , Greenfield Mari 
Published: February 2025

Abstract

Background
Health and social care professional regulators are organisations that ensure their registrants have the correct qualifications and experience to practise in their profession. There are 13 statutory regulators in the United Kingdom (UK) and 29 voluntary accredited registers. Referrals of serious concerns about registrants’ Fitness to Practise (FtP) are investigated by regulators, and can lead to a public hearing. Employers may refer their employee to the regulator, and provide evidence about the concerns about their practice. Communication between the regulator and employer is central to ensure fitness to practise procedures are timely and effective, contributing to patient safety and to the improvement of health and social care professional and organisational practices.

Methods
In this mixed-methods research, semi-structured interviews were conducted with 25 participants who held senior management roles in health and social care organisations in the UK and were responsible for communicating with professional regulators. Descriptive statistics were produced relating to participants’ roles and organisations, and qualitative data was analysed using Template Analysis methodology.

Results
Four themes relating to communication between employers and regulators were identified: Process of regulatory investigation, Point of contact with employers, Local level/informal resolutions, and Organisational learning. Employers frequently described the processes as protracted and stressful for all concerned, and communication with regulators as sporadic and unidirectional during investigations. This style of communication hampered organisational learning from Fitness to Practise cases. Regulators’ employer liaison officers, where they existed, improved communications.

Conclusions
Fitness to Practise processes create the opportunities for not only the determination of whether an individual professional is fit to practise and the supportive measures that might need to be taken if they continue to practice, but also for health and social care organisations to prevent occurrence and re-occurrence of misconduct, thereby improving their services. Regulators’ communication patterns resulted in these employers’ organisational opportunities being missed. It may also lead to over-referral thereby leading to burden on employers, registrants and regulators. Improvements in communication by regulators such as via dedicated employer liaison functions could help organisations access these opportunities as well as promote the objectives of regulators to uphold trust in regulation.