bluuebunny/crossref_metadata_2025_split huggingface dataset:
Existenzgeld für alle !
Authors: Bonnaud Irène 
Published: October 2014

Résumé	L’année 1998 aura été marquée en Allemagne par les "journées d’action mensuelles" des chômeurs et des précaires, les "journées Jagoda", du nom du président de l’ANPE locale (la Bundesanstalt für Arbeit de Nuremberg) qui a la lourde tâche d’annoncer chaque mois les nou-veaux chiffres du chômage. « Les journées d’action mensuelles ont montré qu’à l’encontre de toutes les idées reçues fondées sur des enquêtes pseudo-scientifiques, les chômeurs sont tout à fait capables de s’organiser et d’accomplir des actes de (...)
La Construction / Der Bau
Authors: Müller Heiner 
Published: October 2014

Résumé	Heiner Müller a écrit La Construction en 1963-1964, et la pièce fut publiée en RDA dans la revue Sinn und Form au printemps 1965. En décembre, les répétitions dirigées par Benno Besson furent interdites après intervention du Comité Central de la SED.
El menfi (L'exilé) — extraits
Authors: Rouabhi Mohamed 
Published: October 2014

Résumé	La pièce El menfi (L’exilé) de Mohamed Rouabhi a été créée dans une mise en scène de Nadine Varoutsikos le 21 juillet 2000 à Ramallah, en Palestine. Elle sera jouée en Janvier 2001 à Épinay-sur-Seine, en France.
Topographic Analysis of the Centration of the Treatment Zone After SMILE for Myopia and Comparison to FS-LASIK: Subjective Versus Objective Alignment
Authors: Lazaridis Apostolos , Droutsas Konstantinos , Sekundo Walter 
Published: October 2014

PURPOSE:
To evaluate the centration of the treatment zone after small incision lenticule extraction (SMILE) and compare it to femtosecond laser-assisted LASIK (FS-LASIK).

METHODS:
Sixty-nine myopic eyes of 36 patients who underwent SMILE were compared to 69 myopic eyes of 36 patients treated with FS-LASIK. All procedures were performed by a single surgeon using the VisuMax platform (Carl Zeiss Meditec, Jena, Germany). The Pentacam (Oculus Optikgeräte GmbH, Wetzlar, Germany) was used for preoperative and postoperative topography and pachymetry. The centration of the treatment zone was estimated pachymetrically by the distance of the thickest point on the corneal thickness differential map from the topographical center of the entrance pupil and the coaxial corneal light reflex.

RESULTS:

In SMILE cases, the mean decentration of the lenticule from the center of the entrance pupil was 0.326 ± 0.196 mm (range: 0.014 to 1.062 mm), whereas the distribution of the lenticule centers demonstrated a nasalization pattern. In FS-LASIK cases, this value was 0.452 ± 0.224 mm (range: 0.02 to 1.040 mm), whereas the ablation centers were distributed randomly. In relation to the coaxial corneal light reflex, the decentration in SMILE was 0.315 ± 0.211 mm (range: 0.0 to 1.131 mm), whereas FS-LASIK eyes demonstrated a mean decentration of 0.516 ± 0.254 mm (range: 0.103 to 1.265 mm). The decentration from the reference point of its technique (coaxial corneal light reflex in SMILE, the entrance pupil center in FS-LASIK) was significantly more extended in the FS-LASIK group (
P
< .001).

CONCLUSIONS:
The centration of the treatment zone as measured by the Pentacam was better for patient-controlled fixation during SMILE than active eye tracker-assisted FS-LASIK.

[
J Refract Surg.
2014;30(10):680–686.]
Impact of Personality Characteristics on Patient Satisfaction After Multifocal Intraocular Lens Implantation: Results From the “Happy Patient Study”
Authors: Mester Ulrich , Vaterrodt Thomas , Goes Frank , Huetz Werner , Neuhann Irmingard , Schmickler Stefanie , Szurman Peter , Gekeler Katrin 
Published: October 2014

PURPOSE:
This prospective multicenter study assessed personality characteristics that may influence patient satisfaction after implantation of multifocal intraocular lenses (MIOLs).

METHODS:
One hundred eighty-three patients who underwent bilateral implantation of different MIOLs were enrolled. Uncorrected and corrected distance visual acuity for distance and near (ie, UDVA, UNVA, CDVA, and CNVA) were assessed preoperatively and 3 and 6 months after implantation. Before surgery, personality characteristics were evaluated using a questionnaire based on the NEO Personality Inventory Test and the Compulsiveness Inventory Test. At the 3- and 6-month postoperative visits, patients answered a questionnaire concerning overall satisfaction, need for spectacles at different distances, visual function at different distances and lighting conditions, photic phenomena, and ease of performing daily activities.

RESULTS:
Three months after surgery (n = 163), mean CDVA was 0.03 ± 0.09 logMAR, UDVA was 0.05 ± 0.09 logMAR, and UNVA was 0.04 ± 0.11 logMAR. At the 6-month visit (n = 131), mean CDVA was 0.02 ± 0.07 logMAR, UDVA was 0.06 ± 0.09 logMAR, and UNVA was 0.05 ± 0.01 logMAR. Most patients (82.2%) would opt for an MIOL again, 3.7% would not, and 14.1% were uncertain. Overall satisfaction with the procedure was correlated to low astigmatism, good visual function, low spectacle dependence, and less halos or glare. The personality characteristics of compulsive checking, orderliness, competence, and dutifulness were statistically significantly correlated to subjective disturbance by glare and halos.

CONCLUSIONS:
Postoperative patient satisfaction after MIOL implantation is correlated to visual performance, spectacle independence, and less photic phenomena. Personality characteristics have an impact on subjective disturbance by photic phenomena and thus are important for patient satisfaction.

[
J Refract Surg
2014;30(10):674–678.]
Differences in the Corneal Biomechanical Changes After SMILE and LASIK
Authors: Wang Danyang , Liu Manli , Chen Yile , Zhang Xiaoying , Xu Yangtao , Wang Jianchao , To Chi-ho , Liu Quan 
Published: October 2014

PURPOSE:
To compare the corneal biomechanical properties before and after small incision lenticule extraction (SMILE) and femtosecond laser-assisted LASIK in different levels of myopia with the Ocular Response Analyzer (Reichert Ophthalmic Instruments, Depew, NY).

METHODS:
A total of 187 and 79 eyes that received SMILE or LASIK, respectively, between January and June 2013 at Zhongshan Ophthalmic Center were enrolled in this study. Patients were grouped according to surgery type (SMILE or LASIK) and −6.00 diopters (D) or less (⩽ −6.00 D) or myopia greater than −6.00 D (>−6.00 D). Corneal hysteresis, corneal resistance factor, and 37 waveform parameters were recorded and compared preoperatively and at 1 week and 1 and 3 months postoperatively.

RESULTS:

There was a significant decrease of corneal hysteresis, corneal resistance factor, p1area, and p2area, and an increase of path1 and path2 in both SMILE and LASIK. In myopia −6.00 D or less, the differences between SMILE and LASIK were not significant (
P
> .05), but in myopia greater than −6.00 D, the corneal hysteresis, corneal resistance factor, p1area, and p2area decreased significantly more in LASIK than in SMILE (
P
< .05).

CONCLUSIONS:
When comparing SMILE with LASIK, myopia was greater than −6.00 D, and the corneal hysteresis, corneal resistance factor, p1area, and p2area decrease was less after SMILE.

[
J Refract Surg
. 2014;30(10):702–707.]
Dendritic Cell Maturation and Survival Are Differentially Regulated by TNFR1 and TNFR2
Authors: Maney Nicola J. , Reynolds Gary , Krippner-Heidenreich Anja , Hilkens Catharien M. U. 
Published: October 2014

Abstract
The capacity of dendritic cells (DC) to regulate adaptive immunity is controlled by their maturation state and lifespan. Although TNF is a well-known maturation and survival factor for DC, the role of the two TNFR, TNFR1 and TNFR2, in mediating these effects is poorly understood. By using unique TNF variants that selectively signal through TNFR1 and/or TNFR2, we demonstrate differential functions of TNFR in human monocyte-derived and blood CD1c+ DC. Activation of TNFR1, but not TNFR2, efficiently induced DC maturation, as defined by enhanced expression of cell surface maturation markers (CD83, CD86, and HLA-DR) as well as enhanced T cell stimulatory capacity. In contrast, both TNFR1 and TNFR2 significantly protected DC against cell death, indicating that innate signals can promote DC survival in the absence of DC maturation. We further show differential activation of NF-κB signaling pathways by the TNFR: TNFR1 activated both the p65 and p52 pathways, whereas TNFR2 triggered p52, but not p65, activation. Accordingly, the p65 NF-κB pathway only played a role in the prosurvival effect of TNFR1. However, cell death protection through both TNFR was mediated through the Bcl-2/Bcl-xL pathway. Taken together, our data show that TNFR1, but not TNFR2, signaling induces DC maturation, whereas DC survival can be mediated independently through both TNFR. These data indicate differential but partly overlapping responses through TNFR1 and TNFR2 in both inflammatory and conventional DC, and they demonstrate that DC maturation and DC survival can be regulated through independent signaling pathways.
Antigen-Specific Immunotherapeutic Vaccine for Experimental Autoimmune Myasthenia Gravis
Authors: Luo Jie , Lindstrom Jon 
Published: October 2014

Abstract
Myasthenia gravis (MG) and experimental autoimmune myasthenia gravis (EAMG) are caused by Ab-mediated autoimmune responses to muscle nicotinic acetylcholine receptors (AChRs) that impair neuromuscular transmission, thereby causing muscle weakness. Previously, we discovered that i.p. injection of a therapeutic vaccine consisting of bacterially expressed cytoplasmic domains of human AChR subunits reduced the development of chronic EAMG in rats. In this article, we show that immunization with the therapeutic vaccine in adjuvants does not induce EAMG and, thus, is safe. The potency and efficacy of the therapeutic vaccine were greatly increased by s.c. administration of repeated low doses in IFA. Onset of chronic EAMG could be prevented. Established chronic EAMG could be rapidly reversed, modeling therapy of chronic MG. Therapy reduced pathological Abs assayed by immune precipitation of a main immunogenic region chimera. Successfully treated rats exhibited long-term resistance to reinduction of EAMG, suggesting a lasting cure of MG. A long-term effect of therapy was to change the isotype of the pathogenic Ab response from IgG2b, which fixes complement, to IgG1, which does not. Prevention and reversal of chronic EAMG was not caused by the isotype switch, but the isotype switch may contribute to resistance to reinduction of EAMG. Immunization with AChR cytoplasmic domains in adjuvant is promising as a safe, Ag-specific, potent, effective, rapidly acting, and long-lasting therapeutic approach to MG.
Feeding decisions in advanced dementia
Authors: Harwood RH 
Published: October 2014

When close to death, people stop eating. In neurodegenerative conditions swallowing may become unsafe, and artificial nutrition and hydration (ANH) may be proposed or requested. But nutrition is surrounded by other considerations: opportunity, help, environment, enjoyment, mood, social being and symbolic importance. Poor care or deliberate attempts to end life might also result in poor nutrition and dehydration. Decisions about ANH are open to conventional ethical analysis and subject to mental capacity law. Most people with appetite or swallowing failure have advanced dementia and lack capacity. Determining someone’s best interests means considering values and preferences, previous and current wishes, and requires consultation with families and other carers. Short-term prognosis is difficult to judge in non-malignant conditions. We often do not know the views of the individual. Moreover, we are unsure if ANH can achieve the goals intended of it – there is little evidence that tube feeding prolongs life, prevents aspiration or improves wellbeing. Palliative care and best practice dementia care have much in common. Open communication, good relationships with families and carers, skilled approaches to problems and respect for individuals and their diversity. Modified oral feeding will be appropriate for most; ANH is rarely appropriate, but some individuals and their families feel differently. Careful assessment for potentially treatable causes of swallowing and appetite problems, honest communication about uncertainties over prognosis and the impact of interventions and ascertainment of individuals’ values and beliefs make for better care for people with dementia and better decisions about feeding.
In vitro Air Removal Characteristics of Two Neonatal Cardiopulmonary Bypass Systems: Filtration May Lead to Fractionation of Bubbles
Authors: Stehouwer Marco C. , Kelder Johannes C. , van Oeveren Willem , de Vroege Roel 
Published: October 2014

Introduction of gaseous microemboli (GME) into the arterial line of a pediatric cardiopulmonary bypass (CPB) circuit may lead to cognitive decline and adverse outcomes of the pediatric patient. Arterial filters are incorporated into CPB circuits as a safeguard for gross air and to reduce GME. Recently, arterial filters were integrated in two neonatal oxygenators to reduce volume and foreign surface area. In this study a clinical CPB scenario was simulated. The oxygenators, the corresponding venous reservoirs and the complete CPB circuits were compared regarding air removal and bubble size distribution after the introduction of an air bolus or GME. During a GME challenge, the Capiox FX05 oxygenator removed a significantly higher volume of GME than the QUADROX-i Neonatal oxygenator (97% vs. 86%). Detailed air removal characteristics showed that more GME in the range of 20-50 μm were leaving the devices than were entering. This phenomenon seems to be more present in the Capiox FX05. The circuits were also challenged with an air bolus. Each individual component tested removed 99.9%, which resulted in an air volume reduction of 99.99% by either complete CBP circuit. Overall, we conclude that both CPB systems were very adequate in removing GME and gross air. The air removal properties of both systems are considered safe and reliable. Detailed GME distribution data show that the Capiox FX05 showed more small GME (<50 μm) due to fractionation of larger GME when compared to the QUADROX-i Neonatal. We may conclude that filtration may lead to fractionation.
Hydraulic and Hemodynamic Performance of a Minimally Invasive Intra-arterial Right Ventricular Assist Device
Authors: Hsu Po-Lin , Graefe Roland , Boehning Fiete , Wu Chen , Parker Jack , Autschbach Rüdiger , Schmitz-Rode Thomas , Steinseifer Ulrich 
Published: October 2014

Right ventricular assistance is still in the early phase of development compared to left ventricular assist device (LVAD) technology. In order to provide flexible pulmonary support and potentially reduce the known complications, we propose a minimally invasive right ventricular assist device (MIRVAD), located in the pulmonary artery (PA) and operating in series with the right ventricle (RV). The MIRVAD is an intra-arterial rotary blood pump containing a single axial impeller, which is not enclosed by a rigid housing but stent-fixed within the vessel. The impeller geometry has been designed with the assistance of analytical methods and computational fluid dynamics (CFD). The hydraulic performance of the impeller was evaluated experimentally with a customized test setup using blood synthetic medium (HES). The blade-tip clearance (BTC) was varied between 0.25-4.25 mm to evaluate the effect of different PA sizes on impeller performance. Furthermore, the Langrangian particle-tracking method was used to estimate the level of hemolysis and generate numerical blood damage indexes. The impeller design generated 25.6 mmHg for flow rates of 5 lpm at a speed of 6,000 rpm at the baseline condition, capable of providing sufficient support for the RV. The BTC presented a significant effect on the static pressure generation and the efficiency, but the operational range is suitable for most vessel sizes. The numerical results demonstrated a low risk of blood damage at the design point (mean Lagrangian damage index 2.6 * 10-7). The preliminary results have encouraged further impeller optimization and development of the MIRVAD.
Pore Size – a Key Property for Selective Toxin Removal in Blood Purification
Authors: Harm Stephan , Falkenhagen Dieter , Hartmann Jens 
Published: October 2014

Purpose Extracorporeal blood purification systems based on combined membrane/adsorption technologies are used in acute liver failure to replace detoxification as well as to remove inflammatory mediators in sepsis patients. In addition to coating and chemical modification of the surface, pore size significantly controls the selectivity of adsorption materials. Methods This study addresses the adsorption of albumin bound liver toxins, cytokines, and representative plasma compounds on three adsorbents which differ only in pore size distribution. All three adsorbents are based on hydrophobic poly(styrene-divinylbenzene) copolymer matrices and have mean pore sizes of 15, 30, and 100 nm. Results The pores of adsorbents act as molecular sieves and prevent the entry of molecules that are larger than their molecular cut-off. The results of this study reveal that adsorbents based on styrene-divinylbenzene polymers with 15 nm pores are suitable for cytokine removal, and the same adsorbents with 30-40 nm pores are the best choice for the removal of albumin-bound toxins in the case of liver failure. Adsorbents with very large pores lack selectivity which leads to uncontrolled adsorption of all plasma proteins. Therefore, hydrophobic adsorbents with large pores offer inadequate plasma compatibility and do not fulfill the requirements for blood purification. Conclusions Biocompatibility and efficiency of adsorbents used for blood purification can improved by fine tuning of adsorbent surface pore distributions.
High-Performance Annotation Tagging over Solr Full-text Indexes
Authors: Manghi Paolo , Artini Michele , Bardi Alessia , Atzori Claudio , La Bruzzo Sandro , Mikulicic Marko 
Published: October 2014

<p class="p1">In this work, we focus on the problem of “annotation tagging” over Information <span style="font-size: 10px;">Spaces of objects stored in a full-text index. In such a scenario, tags are </span><span style="font-size: 10px;">assigned to objects by “data curator” users with the purpose of classification, while </span><span style="font-size: 10px;">generic end-users will perceive tags as searchable and browsable object properties. </span><span style="font-size: 10px;">To carry out their activities, data curators need “annotation tagging tools” which </span><span style="font-size: 10px;">allow them to “bulk” tag or untag large sets of objects in temporary work sessions, </span><span style="font-size: 10px;">where they can “virtually” and in “real-time” experiment the effect of their actions </span><span style="font-size: 10px;">before making the changes visible to end-users. The implementation of these tools </span><span style="font-size: 10px;">over full-text indexes is a challenge, since bulk object updates in this context are </span><span style="font-size: 10px;">far from being real-time and in critical cases may slow down index performance. </span><span style="font-size: 10px;">We devised TagTick, a tool which offers to data curators a fully functional annotation </span><span style="font-size: 10px;">tagging environment over the full-text index Apache Solr, regarded as a </span><span style="font-size: 10px;">“de-facto standard” in this area. TagTick consists of a TagTick Virtualizer module, </span><span style="font-size: 10px;">which extends the APIs of Solr to support real-time, virtual, bulk-tagging operations, </span><span style="font-size: 10px;">and a TagTick User Interface module, which offers end-user functionalities </span><span style="font-size: 10px;">for annotation tagging. The tool scales optimally with the number and size of bulk </span><span style="font-size: 10px;">tag operations, without compromising index performance.</span></p>
Adventure Code Camp: Library Mobile Design in the Backcountry
Authors: Ward David , Hahn James , Mestre Lori 
Published: October 2014

<p>This article presents a case study exploring the use of a student Coding Camp as a bottom-up mobile design process to generate library mobile apps. A code camp sources student programmer talent and ideas for designing software services and features. This case study reviews process, outcomes, and next steps in mobile web app coding camps. It concludes by offering implications for services design beyond the local camp presented in this study. By understanding how patrons expect to integrate library services and resources into their use of mobile devices, librarians can better design the user experience for this environment.</p>
Antarctic Circumpolar Current transport and barotropic transition at Macquarie Ridge
Authors: Rintoul S. R. , Sokolov S. , Williams M. J. M. , Peña Molino B. , Rosenberg M. , Bindoff N. L. 
Published: October 2014

AbstractTheory and numerical simulations suggest that topographic interactions are central to the dynamics of the Antarctic Circumpolar Current (ACC), but few observations are available to test these ideas. We use direct velocity measurements, satellite altimetry, and an ocean state estimate to investigate the interaction of the ACC with the Macquarie Ridge. Satellite altimeter data show that the Subantarctic Front crosses the ridge through a gap immediately north of Macquarie Island. Yearlong current meter records reveal strong deep mean flow (> 0.2 m s−1 at 3000 m) and substantial transport (52 ± 8 × 106 m3 s−1) in the 50 km wide gap. The ACC becomes much more barotropic at the ridge. Acceleration of the deep jet is balanced by the ageostrophic along‐gap pressure gradient, convergence of zonal momentum by the mean vertical velocity, and dissipation. The study helps explain how the ACC negotiates large topographic obstacles and highlights the role of local, nonlinear processes in the dynamical balance of the ACC.
Geophysical constraints for terrane boundaries in southern Mongolia
Authors: Guy Alexandra , Schulmann Karel , Munschy Marc , Miehe Jean‐Marc , Edel Jean‐Bernard , Lexa Ondrej , Fairhead Derek 
Published: October 2014

AbstractThe Central Asian Orogenic Belt (CAOB) is a typical accretionary orogen divided into numerous lithostratigraphic terranes. In theory, these terranes should be characterized by contrasting magnetic and gravity signatures owing to their dissimilar petrophysical properties. To test this hypothesis, the extent of tectonostratigraphic terranes in southern Mongolia was compared with the potential field data. The analysis reveals that the terrane boundaries are not systematically defined by strong gravity and magnetic gradients. The correlation of the magnetic signal with the geology reveals that the magnetic highs coincide with Late Carboniferous to Early Permian volcanic‐plutonic belts. The matched filtering shows a good continuity of signal along the boundaries of these high magnetic anomalies toward the deeper crustal levels which may indicate the presence of deeply rooted tectonomagmatic zones. The axes of high‐density bodies in the western and central parts of the study area are characterized by periodic alternations of NW‐SE trending gravity anomalies corresponding to up to 20 km wide cleavage fronts of Permo‐Triassic age. The matched filtering analysis shows good continuity of signal to the depth of these gravity highs which may indicate presence of deeply rooted high‐strain zones. The magnetic signal is interpreted to be as the result of a giant Permo‐Triassic magmatic event associated with lithosphere‐scale deformation, whereas the gravity pattern is related to the postaccretionary shortening of the CAOB between the North China and Siberia cratons.