bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Role of Leadership Skills of High School Principals in Their Knowledge Management Process Competencies
Authors: Balkar Betül , Şahin Sevilay 
Published: June 2015

<p>School principals play an important role in assisting educational institutions in achieving knowledge and gaining knowledge management competence and hence, as a real knowledge organization, in meeting the needs of the age. In order to realize knowledge management, principals should take an active role both as knowledge managers and leaders. The aim of this study was to examine the extent to which leadership skills of high school principals predicted their knowledge management process competencies. In the context of this purpose, the study also aimed at investigating the relationships between principals’ leadership skills and their knowledge management competencies. The sample of the study realized in a relational screening model was comprised of 573 high school teachers working in Adana province of Turkey. The surveying method was utilized for data collection and the data obtained were statistically analyzed. The results of the study suggest that there is a statistically significant relationship between principals’ knowledge management competencies and their leadership skills and that the high school principals’ leadership skills are a predictor of their knowledge management process competencies. The findings of the study emphasize applicability of knowledge management at schools from a social perspective and point out that leadership of the school principal is a facilitator factor to carry out knowledge management processes at schools. </p>
Explaining the Type of Audience Attitude toward the Content of Religious Medium (Islamic Republic of Iran Broadcasting) (Case Study)
Authors: Roshandel Arbatani Taher , Labafi Somayeh 
Published: May 2015

<p>This article is written to theoretically and empirically explain analytical model. In the model, audience attitude toward the content of religious medium (IRIB) is defined as internal variable and the aspects of audience religiosity, his religious knowledge, and type of religiosity as external variables. Each of the variables formulated in research model has theoretical bases. Research method is survey. Data was collected using a handmade questionnaire which was reliable and valid based on test. The statistical population of the study consisted of Isfahan people (n=300). They were randomly sampled. In this study, the effect of aspects of audience religiosity, type of his religiosity and religious knowledge on his attitude toward the content of religious medium is examined in terms of several hypotheses. The analytical model of the study is designed using AMOS. Model fit indices show that Chi square index indicates numerical value of 3.28. Based on what Schumacher and Lomax (2009) suggest as acceptable (i.e. if it is between 1 and 5), it is a good value. In addition to the above index, other indices are also computed for respective model. One of them is Root Mean Square Error of Estimation (RMSEA). It is obtained 0.078 (i.e. &lt;0.08). </p>
As histórias em quadrinhos (HQ’s) na formação dos professores de Ciências e Biologia
Authors: Tavares Júnior Melchior José 
Published: June 2015

O objetivo desse texto foi refletir sobre HQ's como recurso didático no ensino de Ciências e Biologia. Da experiência como docente do curso de Ciências Biológicas, ministrando a disciplina Metodologia de Ensino desde 2009, inferimos que as HQ's podem ser úteis na educação, os futuros professores aprovam sua utilização, proporiam que seus alunos elaborassem suas próprias HQ's. Alertamos para a adequação conceitual, pois a utilização da HQ pressupõe corrreção absoluta, salvo nos casos em que o professor deseje comparar ao conceito adequado; para a linguagem, uma vez que muitos cartunistas utilizam uma linguagem chula em suas produções; para a imagem, pois os autores constroem personagens que não são facilmente identificados como pessoas ou são animais desconhecidos; para os valores, pois os quadrinhos podem emitir juízos particulares dos autores.
Experiências formativas do outro diferente em ambientes de amizade
Authors: Strieder Roque , Herbert Fabiana 
Published: June 2015

O artigo investiga possibilidades de se firmarem experiências formativas envolvendo as dimensões da amizade e as vivências na amizade, como dinâmicas potencializadoras do reconhecimento do outro. Considera as relações pedagógicas, visando à homogeneização, como portadoras do risco de submeter e excluir o outro e o diferente. Reconhece a necessária prudência diante da complexidade e das dificuldades históricas de compreensão do outro. O estudo tem como base a buscagem em referenciais teóricos e entende que a vivência na amizade permite a construção de visões positivas de mundo, de si e do outro como seres humanos singulares e diversos. A convivência na amizade como um com-sentir contempla cenários de respeito à alteridade, um respeito que passa pela descoberta de si e do outro como exercício dessa convivência.The article investigates possibilities to establish formative experiences involving the dimensions of friendship and experiences in friendship, as dynamic potentiating the recognition of the other. Considers the pedagogical relations, aiming to homogenization, as carriers of the risk of submitting and excluding the other and the different. Recognize the required prudence given the complexity and historical difficulties in understanding the other. The study is based on the search for theoretical references and believes that the experience of friendship allows the construction of positive visions of the world, of themselves and others as unique and diverse human beings. The coexistence in friendship as a consent (feel with) scenarios with respect to otherness, a respect that goes by the discovery of self and other as an exercise of this coexistence.
Stretchable Anisotropic Conductive Film with Position‐Registered Conductive Microparticles Used for Strain‐Insensitive Ionic Interfacing in Stretchable Ionic Sensors
Authors: Park Doowon , Kwak Hyunsu , Kim Seonghyeon , Choi Hyeongseok , Lim Ighyun , Kwak Mingyu , Kim Ik‐Soo , Park Hyeji , Eom In‐Yong , Lee Jung‐Woon , Park Ikbum , Lee Anna , Jeong Unyong 
Published: August 2024

AbstractNumerous approaches are explored to achieve precise position registry of microparticles (MPs) with minimal defects; however, MP assembly in a periodic pattern or an arbitrary manner has been a challenging issue over the past several decades. Utilizing the position‐registered conductive MPs, polymer composites of the MPs are used as anisotropic conductive film (ACF) and soft interfacing. One of the remaining challenges is maintaining the MP positions while producing or utilizing the ACF. This study proposes a simple strategy to produce a stretchable ACF (S‐ACF) by mechanical rubbing, without disturbing the MP positions during the production and use. A practical means of precise MP positioning on a ultraviolet (UV)‐patternable soft template is investigated first. This study investigates, through both experiment and finite element method calculation, the relationship between local adhesion of the template and mechanical rubbing variables (pressure, rubbing velocity, and MP size). Based on this exploration, a fast and simple method to fabricate large‐area S‐ACF is presented. This study demonstrates that the S‐ACF can be used for electronic interfacing in stretchable devices and for ionic interfacing to remove the effect of external mechanical force in ionic sensors.
l‐Asparaginase Bio‐Betters: Insight Into Current Formulations, Optimization Strategies and Future Bioengineering Frontiers in Anti‐Cancer Drug Development
Authors: Sonowal Sukanya , Pathak Kalyani , Das Dibyajyoti , Buragohain Kabyashree , Gogoi Ankita , Borah Nikha , Das Aparoop , Nath Ratul 
Published: August 2024

AbstractCancer remains a persistent global health concern, representing a significant challenge in medical science and patient care. In this context, l‐asparaginase has emerged as a promising therapeutic agent due to its unique ability to deplete circulating asparagine, thereby selectively targeting cancer cells. However, despite its potential, current formulations of l‐asparaginase are not without limitations. Issues such as immunogenicity, short half‐life, and variable efficacy present hurdles in its widespread clinical application. To overcome these hurdles, researchers are focusing on developing bio‐better versions of l‐asparaginase. These bio‐betters aim to enhance stability, reduce immunogenicity, and optimize enzyme kinetics, thus improving treatment outcomes. This review critically assesses the current landscape of l‐asparaginase bio‐betters, offering insights into ongoing formulations and advancements, optimization strategies, and future bio‐engineering frontiers. It discusses modifications to enhance therapeutic properties and explores innovative approaches like in‐silico enzyme engineering and artificial intelligence, highlighting their potential to improve the therapeutic profile of l‐asparaginase. Challenges and debates surrounding the l‐asparaginase mechanism are also addressed. By addressing current challenges and outlining future directions, this review aims to contribute to the advancement of anti‐cancer therapeutics, particularly in the context of l‐asparaginase bio‐better research.
Cationic Adiposomes as a Delivery System for Neogambogic Acid for the Treatment of Multiple Cancers
Authors: Zhang Gaoxin , Zhi Zelun , Pan Bin , Li Zemin , Zhang Shuyan , Wu Zhenzhen , Bu Pengcheng , Cao Zhen , Liu Pingsheng 
Published: August 2024

AbstractNeogambogic acid (NGA) is a potent antitumor drug but faces significant obstacles to clinical application, including extremely poor water solubility and systemic toxicity. To overcome these obstacles, a newly developed nanoparticle, adiposome, that consists of a neutral lipid core wrapped with a phospholipid‐monolayer membrane, is utilized for the delivery of NGA. In this study, NGA‐loaded cationic adiposomes (NGA‐C‐ADs) are constructed in which NGA is encapsulated within the neutral lipid core and surrounded by phospholipids and a cationic lipid. The concentration of NGA in NGA‐C‐ADs achieved is as high as 1.0 mg mL−1, which is 2 000‐fold higher than in aqueous buffer alone. Moreover, in vitro cell tests revealed that NGA‐C‐ADs exhibited higher cytotoxicity against various cancer cell lines compared to free NGA. In addition, in vivo anti‐tumor animal studies demonstrate that NGA‐C‐ADs effectively inhibit tumor growth in subcutaneous CT26 tumor‐bearing mice and also suppress chemically‐induced hepatocellular carcinoma without obvious toxicity to major organs. These findings suggest that NGA‐C‐ADs hold promise as a potential treatment for multiple cancers.
High‐Strength, Antiswelling Directional Layered PVA/MXene Hydrogel for Wearable Devices and Underwater Sensing
Authors: Zhang Shipeng , Guo Fengmei , Gao Xue , Yang Mengdan , Huang Xinguang , Zhang Ding , Li Xinjian , Zhang Yingjiu , Shang Yuanyuan , Cao Anyuan 
Published: August 2024

AbstractHydrogel sensors are widely utilized in soft robotics and tissue engineering due to their excellent mechanical properties and biocompatibility. However, in high‐water environments, traditional hydrogels can experience significant swelling, leading to decreased mechanical and electrical performance, potentially losing shape, and sensing capabilities. This study addresses these challenges by leveraging the Hofmeister effect, coupled with directional freezing and salting‐out techniques, to develop a layered, high‐strength, tough, and antiswelling PVA/MXene hydrogel. In particular, the salting‐out process enhances the self‐entanglement of PVA, resulting in an S‐PM hydrogel with a tensile strength of up to 2.87 MPa. Furthermore, the S‐PM hydrogel retains its structure and strength after 7 d of swelling, with only a 6% change in resistance. Importantly, its sensing performance is improved postswelling, a capability rarely achievable in traditional hydrogels. Moreover, the S‐PM hydrogel demonstrates faster response times and more stable resistance change rates in underwater tests, making it crucial for long‐term continuous monitoring in challenging aquatic environments, ensuring sustained operation and monitoring.
Interpretability of operative and pathological reports for radiotherapy planning of sinonasal carcinomas: An ancillary study of the GORTEC 2016‐02 SANTAL trial
Authors: Labarre Coline , Carsuzaa Florent , Fieux Maxime , Verillaud Benjamin , Moya Plana Antoine , de Gabory Ludovic , Patron Vincent , Ferrand Francois‐Régis , Thariat Juliette 
Published: August 2024

Key points
Interpretation of surgical mapping is essential for postoperative radiotherapy planning.
Operative and pathological reports lack comprehensive information on margins quality and tissue block mapping.
Standardizing reports is essential to reduce uncertainties, aiming for less morbid poRT.
Plasma‐Enabled Process with Single‐Atom Catalysts for Sustainable Plastic Waste Transformation
Authors: Yu Xiao , Rao Zhiqiang , Chen Guoxing , Yang Yuantao , Yoon Songhak , Liu Lina , Huang Zeai , Widenmeyer Marc , Guo Heng , Homm Gert , Kunz Ulrike , Liu Xingmin , Ionescu Emanuel , Molina‐Luna Leopoldo , Tu Xin , Zhou Ying , Weidenkaff Anke 
Published: August 2024

AbstractThe escalating issue of plastic waste generation has prompted the search for an effective solution to address these challenges. In this study, we present a novel plasma‐enabled strategy for the rapid breakdown of various types of plastic wastes, including mixtures, into high‐value carbon nanomaterials and hydrogen. The H2 yield and selectivity achieved through the implemented catalyst‐free plasma‐enabled strategy are 14.2 and 5.9 times higher, respectively, compared to those obtained with conventional thermal pyrolysis under similar conditions. It is noteworthy that this catalyst‐free plasma alone approach yields a significantly higher energy yield of H2 (gH2/kWh) compared to other pyrolysis processes. By coupling plasma pyrolysis with thermal catalytic process, employing of 1 wt . % M/CeO2 (M=Fe, Co, and Ni) atomically dispersed catalysts can further enhance hydrogen production. Specifically, the 1 wt . % Co/CeO2 catalyst demonstrated excellent catalytic performance throughout the 10 cycles of plastic waste decomposition, achieving the highest H2 yield of 46.7 mmol/gplastic (equivalent to 64.4 % of theoretical H2 production) and nearly 100 % hydrogen atom recovery efficiency at the 7th cycle. Notably, the H2 yield achieved over the atomically dispersed Fe on CeO2 surface (1 wt . % Fe/CeO2) in the integrated plasma‐thermal catalytic process is comparable to that obtained with Fe particles on CeO2 surface (10 wt . % Fe/CeO2). This outcome, demonstrated with single‐atom catalysts, offers a promising avenue for cost‐effective and efficient chemical plastic recycling. Through a combination of experimental and computational efforts, we have provided an in‐depth understanding of the catalytic mechanisms of the investigated single atom catalysts in the developed plasma‐enabled process. This innovative and straightforward approach provides a promising and expedient strategy for continuously converting diverse plastic waste streams, including mixed and contaminated sources, into high‐value products conducive to a circular plastic economy.
Proton‐Driven Dynamic Behavior of Nanoconfined Water in Hydrophilic MXene Sheets
Authors: Hou Pengfei , Tian Yumiao , Xie Yu , Li Quan , Chen Gang , Du Fei , Wu Jianzhong , Ma Yanming , Meng Xing 
Published: August 2024

AbstractLiquid water under nanoscale confinement has attracted intensive attention due to its pivotal role in understanding various phenomena across many scientific fields. MXenes serve an ideal paradigm for investigating the dynamic behaviors of nanoconfined water in a hydrophilic environment. Combining deep neural networks and an active learning scheme, here we elucidate the proton‐driven dynamics of water molecules confined between V2CTx sheets using molecular dynamics simulation. Firstly, we have found that the Eigen and Zundel cations can inhibit water‐induced oxidation by adjusting the orientation of water molecules, thus proposing a general antioxidant strategy. Besides, we also identified a hexagonal ice phase with abnormal bonding rules at room temperature, rather than only at ultralow temperatures as other studies reported, and further captured the proton‐induced water phase transition. This highlighted the importance of protons in the maintaining stable crystal phase and phase transition of water. Furthermore, we discussed the conversions of different water structures and water diffusivity with changing proton concentrations in detail. The results provide useful guidance in practical applications of MXenes including developing antioxidant strategies, identifying novel 2D water phases and optimizing energy storage and conversion.
Triazole‐, piperazine‐, and DOPO‐containing eugenol‐based reactive flame retardant for unsaturated polyester resin
Authors: Ozukanar Ozge , Sagdic Gokhan , Çakmakçı Emrah , Özmen Fadime Karaer , Üreyen Mustafa E. , Gunay Ufuk Saim , Durmaz Hakan , Kumbaraci Volkan 
Published: August 2024

AbstractThe flammability of unsaturated polyester resins (UPRs) limits their applications. Herein, a reactive P‐ and N‐containing flame retardant (DPET) having triazole and piperazine rings is reported. The 9,10‐Dihydro‐9‐oxa‐10‐phosphaphenanthrene 10‐oxide (DOPO) was used to introduce P atoms, and eugenol was used to import reactive double bonds to DPET. Different ratios of DPET were mixed with a commercial UPR and the thermal, mechanical, optical, and flame retardancy properties were measured. The addition of 15% of DPET into neat UPR led to a decrease in the water contact angle from 70° ± 2 to 61° ± 2. The gel content values of the UPRs were found to change between 97.5% and 89%. The optical properties of the UPR were adversely affected by the incorporation of DPET. The modulus of the DPET‐containing UPRs increased with increasing amount of DPET and 15% of DPET‐containing UPR displayed a modulus value of 1784 ± 86 MPa. When 15% DPET was added to neat UPR, char yields were increased (from 5.6% to 16.6%). Limiting oxygen index (LOI) values increased with increasing amounts of DPET and reached up to 23.4%. Micro cone calorimeter (MCC) test results showed up to a 20.5% reduction in the peak heat release rate (PHRR) of the UPR when 15% DPET was added.
From mind‐deadness to mindedness, from collaboration to cooperation
Authors: Amir Dana 
Published: August 2024

AbstractLooking at the October 7, 2023, events in Israel, this paper suggests a unique configuration of Bion's minus links, called "broken links." The broken links not only represent a negation of a connection—but also a negation of the object. When the link of Love is broken, it is replaced by a unique formation of Love without an object, in which the lack‐of‐object installs itself as the sole object, replacing the work of mourning with pseudo, blank mourning. When the link of Hate is broken, the result is a murderous version of hatred, one that exceeds any proportion or context. When the link of Knowledge is broken, what ensues is a language that functions as a sealing material: instead of signifying and making differences, it drives to overgeneralize, erase differences, and remove distinctions, losing its metaphorical qualities and reducing to its literal meaning. These broken links lead to another twisted link: the link of solidarity, turning positive solidarity, which is based on cooperation—into negative solidarity, based on collaboration. The discussion suggests the shift from the state of mind‐deadness, characterizing broken links on both sides of the conflict, to the state of mindedness, in which the links are reclaimed and restored.
Muscle Tissue Transcriptome of Idiopathic Inflammatory Myopathy Reflects the Muscle Damage Process by Monocytes and Presence of Skin Lesions
Authors: Izuka Shinji , Umezawa Natsuka , Komai Toshihiko , Sugimori Yusuke , Kimura Naoki , Mizoguchi Fumitaka , Fujieda Yuichiro , Ninagawa Keita , Iwasaki Takeshi , Suzuki Katsuya , Takeuchi Tsutomu , Ohmura Koichiro , Mimori Tsuneyo , Atsumi Tatsuya , Kawakami Eiryo , Suzuki Akari , Kochi Yuta , Yamamoto Kazuhiko , Yasuda Shinsuke , Okamura Tomohisa , Ota Mineto , Fujio Keishi 
Published: August 2024

ObjectiveWe aim to investigate transcriptomic and immunophenotypic features of muscle specimens from patients with idiopathic inflammatory myopathy (IIM).MethodsBulk RNA‐sequencing was performed on muscle biopsy samples from 16 patients with dermatomyositis (DM) and 9 patients with polymyositis (PM). Seven tested positive for anti‐aminoacyl transfer RNA synthetase antibodies in the patients with DM (ARS‐DM). We conducted weighted gene coexpression network analysis (WGCNA), differentially expressed gene (DEG) analysis, and gene set variation analysis to assess contributions of specific pathways. Cell proportions in muscle specimens were estimated using a deconvolution approach.ResultsWGCNA revealed significant positive correlations between serum creatine kinase (CK) levels and gene modules involved in cellular respiration, phagocytosis, and oxidative phosphorylation (OXPHOS). Significant positive correlations were also observed between CK levels and proportions of CD16‐positive and negative monocytes and myeloid dendritic cells. Notably, patients with DM demonstrated enrichment of complement and interferon‐α and γ pathway genes compared with those with PM. Furthermore, ARS‐DM demonstrated a higher proportion of Th1 cells and DEGs related to OXPHOS. Additionally, serum Krebs von den Lungen‐6 levels correlated with gene modules associated with extracellular matrix and the transforming growth factor‐β signaling pathway.ConclusionOur study highlights a significant involvement of monocytes in muscle damage and delineates pathologic differences among IIM subtypes. DM was characterized by complement and interferon‐α and γ signaling, whereas ARS‐DM was associated with OXPHOS. Distinctive gene expression variations in muscle specimens suggest that different pathologic mechanisms underlie muscle damage in each IIM phenotype.image
Motor, cognitive, and socio‐cognitive mechanisms explaining social skills in autism and typical development
Authors: Estrugo Yael , Bar Yehuda Shahar , Bauminger‐Zviely Nirit 
Published: August 2024

AbstractChallenges in social functioning are considered a core criterion for diagnosing autism. Although motor skills, executive functioning (EF), and theory of mind (ToM) abilities independently affect social challenges and are interconnected, these abilities' shared contribution to the explanation of social functioning in autism remains under‐investigated. To address this disparity, we examined the motor, EF, and ToM abilities of 148 autistic and non‐autistic youth (ages 6–16 years), evaluating these variables' impact on social ability and their interconnections. Our mediation model exploring the contribution of motor, EF, and ToM skills explained 85% of the variance in social functioning (Social Responsiveness Scale—SRS‐2). Analysis yielded a direct path from study group to SRS‐2‐social (typically developing‐TD > autistic) and two main parallel indirect joint paths: (a) Group ➔ motor ➔ EF ➔ SRS‐2‐social; and (b) Group ➔ motor ➔ ToM ➔ SRS‐2‐social. In two secondary indirect paths, autistic children showed lower motor skills, which in turn explained their higher EF and/or ToM impairment, which in turn explained their higher social skills impairment. Put differently, our results suggest that better EF and TOM proficiency may compensate for poorer motor skills. Findings also indicated that the collective impact of motor, EF, and ToM skills on social functioning, along with the mediating role played by EF and ToM on the social‐motor linkage, may contribute to understanding individual differences in the social functioning of autistic children. These conclusions call for the inclusion of motor, EF, and ToM activities into daily practices to facilitate social functioning.