bluuebunny/crossref_metadata_2025_split huggingface dataset:
High‐Speed Short Infrared Detector Based on Vertical Gr/Se0.2Te0.8/GaAs Heterojunction
Authors: Yang Chong , Yu He , Lian Yunlu , Liu Yiming , Wu Maoyi , Yang Xiutao , Han Jiayue , Dong Xiang , Gou Jun , Zheng Xing , Wu Zhiming , Jiang Yadong , Wang Jun 
Published: July 2024

AbstractIn the domain of high‐performance short‐wave infrared (SWIR) photodetection and imaging, existing technologies predominantly utilize single‐crystal germanium and III‐V semiconductors. Despite their efficacy, these materials are encumbered by laborious synthesis and complex fabrication demands. In this study, the synthesis of large‐area, high‐crystallinity Se0.2Te0.8 thin films through a CMOS‐compatible vacuum thermal evaporation process is reported. A high‐speed, broad‐spectrum photodetector engineered with an innovative Gr/Se0.2Te0.8/GaAs vertical heterostructure is presented, which capitalizes on the augmented carrier mobility and employs graphene innovatively as both a carrier collection interface and an electrode. This configuration facilitates a remarkably swift response time of 800 ns/1 µs at the crucial 1310 nm wavelength for optical communications. Moreover, the fabrication of a 5 × 5 array device demonstrates substantial SWIR imaging capabilities at ambient conditions, marking a paradigm shift in uncooled infrared imaging and communication technologies. This work not only extends the boundaries of SWIR photodetector performance but also underscores the potential of novel material systems in high‐speed optical applications.
Efficient Manipulation of Near‐Field Terahertz Waves: Individually Addressable Transmissive Meta‐Device
Authors: Wang Peng , Fu Xiaojian , Yang Jun , Fu Yuan , Cai Qingdong , Liu Yujie , Yang Silei , Shi Jianshu , Zheng Shilie , Cui Tie Jun 
Published: July 2024

AbstractDue to the powerful capability in manipulating electromagnetic (EM) waves, digital coding and programmable metasurfaces have found vast application prospects across numerous areas such as next‐generation wireless communications and digital holography. Liquid crystals (LCs), as dielectric materials with significant birefringence effect over a wide frequency range, provide a cost‐effective solution for achieving the programmable metasurfaces and flexible EM manipulations, especially in the terahertz (THz) band. Different from the conventional 1D control and single functionality of transmissive LC‐based devices, here, a 16 × 16 addressable amplitude‐phase coding meta‐device is proposed to support for frequency multiplexing by using the film on glass (FOG) technology. Both numerical simulations and experimental results demonstrate that the meta‐atom exhibits an amplitude modulation depth over 90% and a phase tuning range ≈180° at two distinct frequencies, and hence the single meta‐device can provide multifunctional EM applications, including near‐field printing imaging, 3D THz energy convergence, and zero‐order Bessel beam generation. The proposed strategy paves a way for constructing highly integrated and high‐performance THz multifunctional information processing systems.
Biodegradable Magnetic Vesicles for Magnetic Hyperthermia Stimulated Drug Release
Authors: Li Xin , Liu Ya , Chen Xing , Zhao Chenxi , Huang Mengya , Shan Kui , Zhou Xun , Liu Xing 
Published: July 2024

AbstractMagnetic nanomaterials have emerged as an effective drug‐delivery platform for targeted imaging and therapy. However, it remains challenging to fabricate biodegradable magnetic nanoparticles with controllable drug release behaviors and strong magnetic responsiveness. Here an asiaticoside‐loaded biodegradable magnetic vesicle is developed based on the self‐assembly of amphiphilic block copolymer tethered superparamagnetic iron oxide nanoparticles. Thanks to the collective properties, the magnetic vesicles show stronger magnetic responsiveness than individual nanoparticles. Additionally, the magnetic vesicles are dissociated within weeks owing to the biodegradable polymer backbone, which can significantly improve the long‐term biocompatibility of the nanomaterials. The asiaticoside‐loaded magnetic vesicles can readily release the payloads in an alternating magnetic field, likely due to the rising local temperature over the phase transition temperature of the polymers attached on nanoparticles. This work provides new insights into the design and construction of biodegradable magnetic nanomedicines for targeted drug delivery.
Correlation Between Side‐Chain Arrangement and Main‐Chain Helix Conformation in Liquid Crystalline Syndiotactic Poly(Substituted Methylene)s Bearing Cyanobiphenyl Mesogens
Authors: Kiyoura Masamichi , Koshimizu Noboru , Shikinaka Kazuhiro , Shigehara Kiyotaka , Tokita Masatoshi 
Published: July 2024

AbstractThis study focuses on the helical conformation of the main chain of syndiotactic poly(substituted methylene)s with 4‐cyanobiphenyl (CB) moieties incorporated at the ends of the alkyloxycarbonyl side chains. The polymers are designated as PCBn, where n is the number of methylene units in the spacer between the main chain and CB. PCB6 and PCB8 assemble the side chains into layers without positional order within the layers. Meanwhile, PCB10 and PCB12 assemble the side chains into layers with a short‐range positional order. Each CB moiety at a side chain end is bonded to a carbon atom, which is arranged along the helical main chain contour, and its position correlates with that of the carbon atom. As the temperature increases, PCB10 undergoes a phase transition, losing the positional order of the side chains within a layer, which alters the main chain conformation. Consequently, the positions of the side‐chain CB moieties affect the helical conformation of the main chain. In contrast, PCB12 maintains the main chain conformation when undergoing a phase transition similar to that of PCB10. PCB12 with the longer spacer allows the main chain to adopt a helix conformation, which is independent of the positions of side‐chain CB moieties.
Development of Ductile‐Sticky Bone Fillers from Biodegradable Hydrolyzed Wool‐Keratin and Silk Fibroin
Authors: Bekar Serife , Sezgin Arslan Tugba , Arslan Yavuz Emre 
Published: July 2024

AbstractIn the present study, a method is proposed for preparing novel ductile‐sticky materials that can be used as bone void fillers using hydrolyzed wool‐keratin (WK) and silk fibroin (SF). This methodology uses citric acid as a cross‐linking agent in preparing keratin paste (KP) owing to its non‐toxicity and plasticizing properties. The Keratin paste‐silk fibroin structure (KPSF) is obtained by adding SF, which possesses biocompatible and superior mechanical properties. Methanol treatment is employed on the KPSF mixture to convert the Silk I structure in the SF to Silk II, resulting in a water‐insoluble and tightly packed proteinaceous structure. The physicochemical properties of both bioscaffolds are investigated and discussed in detail by comparison. Based on the findings, the presence of SF in the KPSF structure contributed to properties such as flexibility and porosity. In ovo CAM analysis reveals that both materials exhibit proangiogenic properties and are biocompatible. KP and KPSF bioscaffolds can be converted into ductile‐sticky forms by adding water. It believes that these forms can easily apply to bone defect areas, particularly cavitary bone defects. Furthermore, KPSF bioscaffolds, with better mechanical properties, can be considered candidates for use in non‐load‐bearing bone tissue engineering applications.
Single‐cell RNA sequencing reveals reduced intercellular adhesion molecule crosstalk between activated hepatic stellate cells and neutrophils alleviating liver fibrosis in hepatitis B virus transgenic mice post menstrual blood‐derived mesenchymal stem cell transplantation
Authors: Chen Lijun , Huang Yuqi , Zhang Ning , Qu Jingjing , Fang Yangxin , Fu Jiamin , Yuan Yin , Zhang Qi , Li Hang , Wen Zuoshi , Yuan Li , Chen Lu , Xu Zhenyu , Li Yifei , Yan Huadong , Izawa Hiromi , Li Lanjuan , Xiang Charlie 
Published: July 2024

AbstractLiver fibrosis can cause hepatitis B virus (HBV)‐associated hepatocellular carcinoma. Menstrual blood‐derived mesenchymal stem cells (MenSCs) can ameliorate liver fibrosis through paracrine. Single‐cell RNA sequencing (scRNA‐seq) may be used to explore the roadmap of activated hepatic stellate cell (aHSC) inactivation to target liver fibrosis. This study established HBV transgenic (HBV‐Tg) mouse model of carbon tetrachloride (CCl4)‐induced liver fibrosis and demonstrated that MenSCs migrated to the injured liver to improve serological indices and reduce fibrotic accumulation. RNA‐bulk analysis revealed that MenSCs mediated extracellular matrix accumulation and cell adhesion. Liver parenchymal cells and nonparenchymal cells were identified by scRNA‐seq in the control, CCl4, and MenSC groups, revealing the heterogeneity of fibroblasts/HSCs. A CellChat analysis revealed that diminished intercellular adhesion molecule (ICAM) signaling is vital for MenSC therapy. Specifically, Icam1 in aHSCs acted on Itgal/Itgb2 and Itgam/Itgb2 in neutrophils, causing decreased adhesion. The expression of Itgal, Itgam, and Itgb2 was higher in CCl4 group than in the control group and decreased after MenSC therapy in neutrophil clusters. The Lcn2, Pglyrp1, Wfdc21, and Mmp8 had high expression and may be potential targets in neutrophils. This study highlights interacting cells, corresponding molecules, and underlying targets for MenSCs in treating HBV‐associated liver fibrosis.
Risk of Dementia in Parkinson's Disease: A Systematic Review and Meta‐Analysis
Authors: Gibson Lucy L. , Weintraub Daniel , Lemmen Roos , Perera Gayan , Chaudhuri Kallol Ray , Svenningsson Per , Aarsland Dag 
Published: July 2024

AbstractEstimates of the risk of dementia in Parkinson's disease (PDD) vary widely. We aimed to review the incidence of PDD and in a meta‐analysis estimate the pooled annual incidence and relative risk of PDD while also exploring factors that may contribute to heterogeneity between studies. Preferred Reporting Items for Systematic reviews and Meta‐Analyses guidelines were followed and MEDLINE and EMBASE were searched for articles reporting the number of cases of dementia in a population, followed longitudinally, with a minimum of 100 dementia‐free Parkinson's disease (PD) patients at baseline. Meta‐analyses and meta‐regressions were used to estimate the pooled incidence rate of PDD and the relative risk of PDD versus healthy controls (HC). A total of 32 studies were identified, 25 reporting the incidence of PDD and 10 reporting the relative risk of PDD versus HC. The pooled incidence rate of PDD was 4.45 (95% confidence interval [CI], 3.91–4.99) per 100 person‐years at risk, equating to a 4.5% annual risk of dementia in a PD prevalent population. The relative risk of PDD was estimated to be 3.25 (95% CI, 2.62–4.03) times greater than HC. Factors contributing to study heterogeneity and disparities in the estimated risk of PDD include the age of patients, year of recruitment, and study location. Significant gaps remain with no studies identified in several geographical regions. Future studies should stratify by age and standardize reporting to reduce overall heterogeneity. © 2024 The Author(s). Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
Density functional theory study on frustrated Lewis pairs catalyzed C‐H activation of heteroarenes: Mechanism variation tuning by electronic effect
Authors: Shao Youxiang , Xiao Kang , Wang Huize , Liu Yalan 
Published: July 2024

AbstractUnreactive C‐H bond activation is a new horizon for frustrated Lewis pairs (FLPs) chemistry. Although concerted mechanism (Science 2015, 349, 513) and stepwise carbene mechanism (Org. Lett. 2018, 20, 1102) have been proposed for the FLPs catalyzed C‐H bond activation of 1‐methylpyrrole, the influence of electronic properties of FLPs on the reaction mechanism is far away from well‐understood. In this study, an assortment of P‐B type FLPs with different electronic characteristic was employed to study the catalyzed C‐H bond activation of 1‐methylpyrrole by using density functional theory calculations. Detailed calculations demonstrated that the reactivity variation and the reaction mechanism binary of FLPs catalyzed C‐H activation can be varied by tuning electronic effect of Lewis base center. On the one hand, the concerted C‐H activation reactivity is mainly controlled by the electron donation of the lone pair of Lewis base center; thus, the FLPs with electron‐donating substituents (FLP1, FLP2, and FLP3) catalyzed the C‐H bond activation through concerted mechanism. On the other hand, the reactivity of stepwise carbene mechanism is mostly attributed to the vacant orbital of Lewis acid center; as a result, the FLP5 bearing ‐P(C6F5)2 preferred to catalyzed the bond activation through concerted mechanism. In contrast, a metathesis mechanism through strained four‐membered ring transition state is less feasible. These results should provide deeper insight and broader perspective to understand the structure and function of FLPs for rational design of FLPs catalyzed C‐H bond activation.
Correlation between reactivity descriptors and electronic pressures: A different application of SBO orbitals
Authors: García Víctor , Zorrilla David , Fernández Manuel , Sánchez‐Márquez Jesús 
Published: July 2024

AbstractThis research has discovered relationships between atom reactivity parameters (such as electronegativity or hardness) and the pressure exerted on their electronic shells. These relationships are derived from the relationship between the radius of the atom confined within a spherical box and the pressure exerted on the box by its electrons. To determine the pressure corresponding to each radius, it was essential to formulate a set of new basis functions valid for calculating the energy of confined atoms. These new basis functions, Simplified Box Orbitals (SBOs), stem from the previously studied SBOs, but their coefficients are obtained variationally instead of being fitted to a Slater‐Type Orbital (STO), and the powers (R−r)k are selected differently. These differences make them especially suitable for treating confined atoms and distinguishing between “hard” and “soft” confinements. This methodology has proven useful for accurately calculating the properties of various atoms under different pressures, namely H, He, Li, Be, B, C, N, O, F, and Ne. Furthermore, we believe that the new basis functions are suitable for obtaining Gaussian expansions that will enable the treatment of confined molecules, which we intend to study in a subsequent work.
A hydrolyzed N‐propionylthiosuccinimide linker is cleaved by metastable fragmentation, increasing reliability of conjugation site identification in conjugate vaccines
Authors: Ramos‐Bermúdez Pablo E. , Pousa Satomy , Carvalho Paulo , Brant Rodrigo Soares Caldeira , Batista Michel , Hojo Hironobu , Garay Hilda E. , Roscoe Abel , Mallón Alina Rodríguez , Besada Vladimir , Takao Toshifumi , González Luis Javier 
Published: July 2024

AbstractRATIONALEConjugation sites are a quality attribute of conjugate vaccines. Proteolysis of bioconjugates synthesized by maleimide–thiol chemistry generates type 2 peptides with a hydrolyzed thiosuccinimide linker containing information on the conjugation sites. A mass spectrometry (MS)‐cleavable linker could make the identification of conjugation sites by MS more reliable.METHODSFour synthetic type 2 peptides with a hydrolyzed thiosuccinimide linker were analyzed by matrix‐assisted laser desorption ionization (MALDI) MS/MS with and without collision gas. These peptides were also partially labeled with 18O in the linker to confirm the proposed fragmentation mechanism. A conjugate vaccine with the hydrolyzed thiosuccinimide linker was reduced and S‐alkylated, digested with trypsin and analyzed by liquid chromatography–MS/MS using collision‐induced dissociation (CID) and higher‐energy collisional dissociation (HCD) fragmentation methods at a normalized collision energy of 30.RESULTSA metastable fragmentation preferentially cleaves the newly formed pseudopeptide bond within the hydrolyzed thiosuccinimide linker of type 2 peptides to yield P + 71 and C + 98 ions. These ions make the assignment of conjugation sites more reliable. Partial 18O‐labeling and MS/MS analysis confirmed the proposed structures. CID produces these ions as the two most intense signals more favorably than HCD. The latter also yields these ions, guarantees better sequence coverage and promotes other fragmentations in the linker.CONCLUSIONSHydrolyzed thiosuccinimide linker is cleavable in MALDI and electrospray ionization MS/MS analysis by a gas‐phase metastable fragmentation. The resulting fragment ions (P + 71 and C + 98) make the identification of conjugation sites more reliable. These results could be extended to self‐hydrolyzing maleimides, which efficiently stabilize the thiosuccinimide linker upon hydrolysis, in antibody–drug conjugates.
Lead Complexes of 3‐(2‐pyridyl)‐5‐(4‐methoxyphenyl)‐1,2,4‐Triazine: Synthesis, Characterization and Application in Organic Light‐Emitting Diodes (OLEDs)
Authors: Arkak Akbar , Hossaini Sadr Moayad , Marandi Farzin , Fuhrmann Daniel , Janghouri Mohammad 
Published: July 2024

AbstractThree new Pb(II) complexes of 3‐(2‐pyridyl)‐5‐(4‐methoxyphenyl)‐1,2,4‐triazine (PMPT) ligand with different anionic co‐ligands (1: nitrate, 2: perchlorate and 3: isothiocyanate) in 2 : 1 molar ratios of PMPT ligands and lead(II) salts, [Pb(PMPT)2(NO3)2] (1), [Pb(PMPT)2(ClO4)2] (2) and [Pb(PMPT)2(NCS)2] (3) were synthesized and characterized by physicochemical (CHN, FT‐IR and 1H NMR) and single‐crystal X‐ray diffraction methods. By considering the obtained structural parameters, the lead atoms in 1, 2 and 3 have PbN4O4, PbN4O2 and PbN6 environments, respectively, with holodirected (for 1) and hemidirected (for 2 and 3) coordination spheres. We used electro‐optical Pb(II) complexes family as emitting layer to investigate in fabrication of OLEDs. The current–voltage, luminescence‐voltage characteristics and the absorption (Abs) and electroluminescence (EL) properties of the complex have been investigated. The forester radius, quantum yield, and electroluminescence have been studied.
Efficient Chromophore Design with PICT Coupled TICT: Computational Studies on Hyperpolarizabilities of Pyridinium Benzimidazolates
Authors: Sitha Sanyasi 
Published: July 2024

AbstractPreviously synthesized six selected Pyridinium‐Benzimidazolate based zwitterions were investigated in this contribution. Of the selected molecules, two are TICT, two are PICT (twisted and planar intramolecular charge transfer types respectively), and the other two are PICT+TICT types. Generally, TICT vs PICT is the most widely used strategy for chromophore design by earlier researchers. In this work, impacts of PICT+TICT effects (two effects combined in one chromophore), through p‐phenylene bridges, on various fundamental properties like, dipole moments, polarizabilities, hyperpolarizabilities, adiabatic excitations were analyzed. Nonlinear optical (NLO) responses of the six molecules indicate that PICT more efficient than TICT (6‐11‐times enhanced β), and PICT+TICT more efficient than both PICT (~4 times enhanced β) and TICT (20–40 times enhanced β). Current work also shows the role of aromatic p‐phenylene bridge as an efficient communicator between the donor and acceptor, in enhancing the NLO and other response properties. This work suggests that inducing bridge aromatic control to a TICT chromophore (making it to exhibit an amalgamation of PICT and TICT effects) is an effective and efficient strategy in the designing of molecular nonlinear optical chromophores, over either PICT or TICT only.
Thiophene‐Based Multi‐layered 3D Chiral Polymer and Oligomer Containing Aggregate‐Induced Emission and Polarization
Authors: Ai Chan , Zhang Yue , Zhang Sai , Yan Shenghu 
Published: July 2024

AbstractThiophene‐based conjugated polymers show a unique position in the constantly expanding variety of conjugated polymers because of their outstanding optical and conductive characteristics. during the past few decades, many researchers have made significant contributions by developing new methods to create more effective materials for electronic applications. Employing one‐pot Suzuki polycondensation, a unique series of structurally condensed multicolumn/multilayer 3D polymers and oligomers have been developed and synthesized in this research. Polymers were produced with moderate to excellent yields in all instances, as examined by GPC and 1H‐NMR. The results from experiments of optical rotation and AIE investigation, show that the current work will benefit materials research and applications.
A longitudinal examination of appraisal, coping, stress, and mental health in students: A cross‐lagged panel network analysis
Authors: Spătaru Bianca , Podină Ioana R. , Tulbure Bogdan Tudor , Maricuțoiu Laurentiu P. 
Published: July 2024

AbstractIn their seminal Transactional Theory of Stress, Lazarus and Folkman described a complex adaptation mechanism that involves appraisal and coping processes that lead to the subjective experience of stress. In this study, we examined the temporal order of all components of this theory using a cross‐lagged panel analysis. A sample of 354 students (62.10% female, mean age = 20.63 y.o.) participated in a 5‐week study and completed weekly self‐reported measures of prospective appraisal, coping, core burnout, and mental health (i.e. depression, anxiety, and stress). Using cross‐lagged panel network analyses, we analyzed how each measured variable is predicted by all variables from the previous measurement moment. Convergent with the transactional stress theory, we found that threat appraisals and negative self‐perception predicted future anxiety and depression. Contrary to expectations, core burnout and somatization emerged as significant predictors of poor mental health outcomes, suggesting a self‐perpetuating spiral. Furthermore, our study highlighted the importance of recognizing the bidirectional connections between appraisals, coping strategies, and mental well‐being.
Modulating *OOH Adsorption on RuO2 for Efficient and Durable Acidic Water Oxidation Electrocatalysis
Authors: Yin Tingting , Yang Mengying , Tian Meng , Jiang Wei , Liu Guigao 
Published: July 2024

AbstractAcidic water electrolysis is of considerable interest due to its higher current density operation and energy conversion efficiency, but its real industrial application is highly limited by the shortage of efficient, stable, and cost‐effective acidic oxygen evolution reaction (OER) electrocatalysts. Here, an electrocatalyst consisting of Ni‐implanted RuO2 supported is reported on α‐MnO2 (MnO2/RuO2‐Ni) that shows high activity and remarkable durability in acidic OER. Precisely, the MnO2/RuO2‐Ni catalyst shows an overpotential of 198 mV at a current density of 10 mA cm−2 and can operate continuously and stably for 400 h (j = 10 mA cm−2) without any obvious attenuation of activity, making it one of the best‐performing acid‐stable OER catalysts. Experimental results, in conjunction with density functional theory calculations, demonstrate that the interface electron transfer effect from RuO2 to MnO2, further enhanced by Ni incorporation, effectively modulates the adsorption of OOH* and significantly reduces the overpotential, thereby enhancing catalytic activity and durability.