bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of a single‐visit approach to cervical cancer screening and treatment in Guyana: Feasibility, effectiveness and lessons learned
Authors: Martin Caitlin E. , Tergas Ana I. , Wysong Megan , Reinsel Maureen , Estep Deborah , Varallo John 
Published: June 2014

AbstractAimTo evaluate a cervical cancer prevention project in Guyana utilizing visual inspection with acetic acid (VIA) and immediate cryotherapy in a single‐visit approach; and to identify lessons learned to inform the improvement of cervical cancer prevention programs in Guyana and other low‐resource settings.MethodsService records from January 2009 to June 2012 were analyzed for 18 cervical cancer prevention sites across Guyana. Records included women's HIV status, data on visual inspection with acetic acid screening and treatment status for women's initial and 1‐year follow‐up screenings, provider training and retention. A process evaluation was conducted in 2011 to identify programmatic strengths and interventions for integration, scale‐up and sustainability.ResultsDuring the 42‐month interval, 21 597 new screenings were performed, reaching 95% of HIV+ women enrolled in care and 17% of women aged 25–49 years in Guyana. The VIA+ rate was 13% (n = 2806); 85% of women eligible for cryotherapy received immediate treatment. Half of VIA+ women treated with cryotherapy or loop electrosurgical excision procedure returned for a 1‐year follow‐up screening (n = 1027); 95% were VIA– at the second screening. Non‐physician providers were more likely to continue offering services than physicians. Most programmatic challenges were related to systemic rather than technical/clinical issues.ConclusionThe single‐visit approach‐based program is feasible, effective, and when scaled up, likely to have an impact on overall incidence of cervical cancer. Services can be shifted to non‐physicians for scale‐up of high‐quality cervical cancer prevention services nationally. To ensure sustainability and expansion, support structures should be prioritized.
Menopausal cardiomyopathy: Does it really exist? A case–control deformation imaging study
Authors: Keskin Kurt Raziye , Nacar Alper B. , Güler Ayşe , Silfeler Dilek B. , Buyukkaya Eyup , Karateke Atilla , Kurt Mustafa , Tanboga Ibrahim H. 
Published: June 2014

AbstractAimWe aimed to evaluate and compare the left ventricular (LV) functions of pre‐ and postmenopausal women at similar ages with none of the known cardiovascular risk factors, by both conventional and advanced echocardiographic methods such as 2‐D strain imaging via speckle tracking echocardiography.MethodsThe study population consisted of 40 healthy postmenopausal women aged 45–50 years and 40 healthy premenopausal women of the same age group. None of the subjects had any cardiovascular risk factors and were on hormone replacement therapy. LV strain and strain rate parameters were measured by 2‐D strain imaging. The main outcome measure was effect of menopause on LV function.ResultsThere were no significant differences between the pre‐ and postmenopausal groups with regard to conventional echocardiographic parameters. LV longitudinal strain and LV early diastolic strain rate values were significantly lower in the postmenopausal group when compared to the premenopausal group. Also, there was a significant negative correlation between LV global strain and serum follicle‐stimulating hormone (r = –0.349, P = 0.002).ConclusionOur study results demonstrated that healthy postmenopausal women had lower LV longitudinal strain values when compared to the healthy premenopausal women of the same age group by speckle tracking echocardiography.
Trends in laparoscopic surgery for hysterectomy in Korea between 2007 and 2009
Authors: Lee Eun‐Ju , Park Hyoung Moo 
Published: June 2014

AbstractAimsThe aims of this study are to estimate the hysterectomy rate for benign disease and determine recent trends in laparoscopic surgery for hysterectomies, including subtotal, total, and radical hysterectomy, in Korea.Material and MethodsComputerized discharge summaries from private and public hospitals for 2007–2009 were obtained from the Health Insurance Review & Assessment Service. All records listing subtotal and total hysterectomies for benign disease and radical hysterectomies in women aged ≥ 16 years in each period were selected (n = 99 388). All women living in Korea aged ≥ 16 years were the denominator population. Laparoscopic surgery was identified when the code for laparoscopic materials was used. Statistical analysis included a trend test.ResultsThe hysterectomy rates for benign disease were 1.48, 1.49, and 1.52/1000 women aged ≥ 16 years in 2007, 2008, and 2009, respectively, and the overall rate was 1.49/1000 women. The trend increased (P for trend <0.001). The use of laparoscopy for subtotal and total hysterectomies accounted for 43.1% in 2007, 47.7% in 2008, and 52.0% in 2009, which showed a clear increasing trend (P for trend <0.001). The use of laparoscopy for radical hysterectomies comprised 26.7%, 28.7%, and 38.2% of cases in 2007, 2008, and 2009, respectively, an increased trend (P for trend <0.001).ConclusionThe hysterectomy rate for benign disease increased between 2007 and 2009 in Korea. Application of laparoscopy during subtotal, total, and radical hysterectomies has increased significantly.
Evaluation of oxidative stress in placenta of fetal cardiac dysfunction rat model and antioxidant defenses of maternal vitamin C supplementation with the impacts on P‐glycoprotein
Authors: Li Yifei , Fang Jie , Zhou Kaiyu , Wang Chuan , Mu Dezhi , Hua Yimin 
Published: June 2014

AbstractAimThe oxidative stress of placenta during fetal heart dysfunction (FHD) is lack of evaluation. So, we carried out an experiment to explore whether vitamin C (VitC) can be supplied for placental protection under FHD and its impacts on P‐glycoprotein expression.MethodsFetal heart dysfunction was induced by two intra‐amniotic injections of isoproterenol, then (VitC) was supplied. Hematoxylin–eosin (HE) staining was used to evaluate placental histology, and oxidative stress was measured by total antioxidant capacity, total superoxide dismutase and level of advanced oxidation protein products (AOPP), as well as apoptosis rate. Real‐time polymerase chain reaction was adopted to measure the expressions of superoxide dismutase‐1 (Sod‐1), glutathione peroxidase‐1 (Gpx‐1) and endothelial nitric oxide synthase (eNOS) in placenta. Finally, western blot was performed to detect P‐glycoprotein expression.ResultsAll isoproterenol twice‐treated fetuses exhibited significant (P < 0.05) contractile dysfunction by fetal echocardiography compared to others. The HE staining showed severe placental hydrops in the FHD group, and that hydrops could be reduced by VitC treatment. Total antioxidant capacity and total Sod‐1 decreased in FHD and elevated after VitC supplementation. Also, level of AOPP increased in FHD and dropped after VitC supplementation. Analysis of apoptosis demonstrated that there was a mild increase in apoptosis rate of FHD. Reductions of Sod‐1 and eNOS mRNA expression were confirmed in FHD, but these could recovered after VitC supplementation, with the same tendency of the P‐glycoprotein.ConclusionSevere oxidative injuries were identified in placentas of FHD with P‐glycoprotein repression. VitC administration can reduce the oxidative stress and rebuild the protective mechanism of placenta.
Comparison of oxidative status of mouse pre‐antral follicles derived from vitrified whole ovarian tissue and vitrified pre‐antral follicles in the presence of alpha lipoic acid
Authors: Hatami Sahar , Zavareh Saeed , Salehnia Mojdeh , Lashkarbolouki Taghi , Karimi Isaac 
Published: June 2014

AbstractAimThe main goal of this study was to compare developmental competence and oxidative status of vitrified‐warmed pre‐antral follicles (VPF) with pre‐antral follicles derived from vitrified‐warmed ovarian tissue (VOF) in the presence of alpha lipoic acid (ALA).Materials and MethodsOvarian tissue and isolated pre‐antral follicles were exposed to equilibration solution and then vitrification solution. After thawing of LN2 snap‐frozen samples, pre‐antral follicles were cultured with or without ALA for 12 days that followed by hCG‐induced ovulation. MII oocytes were in vitro fertilized and embryo cleavage assessed. Reactive oxygen species (ROS) and total antioxidant capacity (TAC) levels of cultured pre‐antral follicles were measured.ResultsThe rates of survival, antral‐like cavity formation, MII oocytes, fertilization, 2‐cell embryo and blastocyst development were higher in VPF compared to VOF. These rates were higher in ALA‐supplemented groups in comparison to their respective groups. An increase and a decrease in ROS production and TAC levels were observed up to the 96 h during cultivation period, respectively. ROS level was lower in cultured VPF compared to VOF. In ALA‐treated groups, ROS level decreased to reach comparable values of starting point and TAC levels increased after 24 h of culture and then remained constant.ConclusionDevelopmental outcomes showed vitrification of pre‐antral follicles is more appropriate method than that of whole ovarian tissue. Moreover, it seems that inclusion of ALA improved in vitro development of pre‐antral follicles in both vitrified and non‐vitrified samples.
Successful pregnancy in a case of bladder and ovary endometriosis following cystoscopy‐assisted laparoscopic resection
Authors: Chishima Fumihisa , Ichikawa Go , Sato Katsuhiko , Ishige Toshiyuki , Sugitani Masahiko , Yamamoto Tatsuo 
Published: June 2014

AbstractA 34‐year‐old, gravida 0 para 0 Japanese woman visited a regional hospital complaining of dysmenorrhea, hematuria during menstruation, and right inguinal pain. She had a history of dysmenorrhea and three prior rounds of in vitro fertilization with embryo transfer, which were all with transfers of cryopreserved‐thawed single embryos in natural cycles, resulting in no pregnancy. An ultrasound revealed a large 2 × 1‐cm nodule between the bladder and the anterior wall of the uterus and a 3‐cm cystic lesion in the right adnexal area. A combined cystoscopic and laparoscopic resection of the bladder endometriosis and cystectomy of the right endometrioma were carried out. A single ultrasound‐guided transfer of a cryopreserved‐thawed embryo in the cleavage stage was performed 4 months postoperatively, which resulted in an uncomplicated pregnancy. The combined, single procedure was minimally invasive and eradicated the lesions that may have caused the infertility.
Case report: Renal cell carcinoma with metastasis to the myometrium
Authors: Rahbar Haider M. , Kumar Ramesh K. , Dalela Deepansh , Hanna Rabbie , Gupta Nilesh , Rogers Craig G. 
Published: June 2014

AbstractRenal cell carcinoma (RCC) is well known for its ability to metastasize to different organs, but the involvement of gynecological organs is rare. Our case represents the first case of bilateral RCC with metastasis to the myometrium. The patient was a 60‐year‐old woman who underwent bilateral robotic partial nephrectomy surgeries for clear cell RCC, low‐grade, low‐stage with negative margins. Her 1‐year postoperative computed tomography scan showed an enlarging necrotic uterine mass. She underwent a debulking excision, including hysterectomy, with pathology showing metastatic RCC to the uterus. The patient developed widespread metastatic disease, and died months later of metastatic RCC.
Aspects of emotional and physical discomfort in gynecologic examination: A study of Turkish women
Authors: Tugut Nilufer , Golbasi Zehra 
Published: June 2014

AbstractAimThis cross‐sectional study was carried out to determine physical and emotional discomforts experienced before and after a gynecologic examination by women who presented to the outpatient clinic of the gynecology and obstetrics department at a university hospital.Material and MethodsThe sample of study was composed of 248 women. Data were collected with a survey form developed by researchers. T‐test and variance analysis were used in statistical analysis.ResultsEmotional discomfort before the examination was felt by 80.2% of the women, while 80.6% stated they felt emotional discomfort after the examination. Physical discomfort before the examination was experienced by 67.3% of the women, while 76.6% stated that they felt physical discomfort after the examination. The emotional discomfort mean score was 5.02 ± 3.24 before examination and 4.62 ± 3.23 after examination (P > 0.05). The physical discomfort mean score was 3.38 ± 3.12 before examination and 3.94 ± 3.02 after examination and the difference between mean scores was statistically significant (P < 0.05).ConclusionThe women felt more physical discomfort during the examination than they anticipated beforehand. The emotional discomfort in women who preferred a female physician was significantly higher than in those who preferred a male physician or who had no preference on the sex of their physician.
Obstetrical disseminated intravascular coagulation score
Authors: Kobayashi Takao 
Published: June 2014

AbstractObstetrical disseminated intravascular coagulation (DIC) is usually a very acute, serious complication of pregnancy. The obstetrical DIC score helps with making a prompt diagnosis and starting treatment early. This DIC score, in which higher scores are given for clinical parameters rather than for laboratory parameters, has three components: (i) the underlying diseases; (ii) the clinical symptoms; and (iii) the laboratory findings (coagulation tests). It is justifiably appropriate to initiate therapy for DIC when the obstetrical DIC score reaches 8 points or more before obtaining the results of coagulation tests. Improvement of blood coagulation tests and clinical symptoms are essential to the efficacy evaluation for treatment after a diagnosis of obstetrical DIC. Therefore, the efficacy evaluation criteria for obstetrical DIC are also defined to enable follow‐up of the clinical efficacy of DIC therapy.
Takotsubo cardiomyopathy after cesarean: A case report and published work review of pregnancy‐related cases
Authors: Minatoguchi Miki , Itakura Atsuo , Takagi Eiji , Nishibayashi Manabu , Kikuchi Mariko , Ishihara Osamu 
Published: June 2014

AbstractTakotsubo cardiomyopathy (TCM) primarily affects postmenopausal women and is an important differential diagnosis of acute coronary syndrome. We describe a rare case of post‐partum TCM, and present a published work review of the cases of pregnancy‐associated TCM. A 24‐year‐old Japanese woman pregnant with twins suffered from premature membrane rupture at 31 gestational weeks. Following emergency cesarean delivery, she complained of sudden dyspnea. Transthoracic echocardiography revealed an inverted Takotsubo pattern (ejection fraction, 46%). On post‐delivery day 8, wall motion abnormalities subsided, and she was discharged on post‐delivery day 16. We reviewed 18 relevant cases of peripartum TCM from the published work. Among them, 16 cases were post‐partum and two cases occurred during pregnancy. Most women (81%) underwent cesarean delivery, and the first symptoms of TCM appeared during surgery in 38% of the cases. The dominant symptoms were chest pain (44%) and dyspnea (28%). Most cases (94%) exhibited electrocardiogram abnormalities, including ST changes and T‐wave inversion. Serum levels of cardiac enzymes were abnormally high in 92% of the cases. Repeated echocardiography documented normalized left ventricular systolic function within 6 months in all cases. This case and review emphasize that TCM may be concealed in post‐partum women by symptoms undistinguishable from acute coronary syndrome, peripartum cardiomyopathy or pulmonary thromboembolism, and that echocardiography may be a useful tool to distinguish them.
A new quantitative screening method for removable prosthesis using pressure‐indicating paste
Authors: Sanagawa T. , Hara T. , Minagi S. 
Published: June 2014

SummaryAim of this study was to quantitatively evaluate the adaptation of the denture base to the mucosa using a non‐setting pressure‐indicating paste and to examine the relationship between quality of fit and the need for denture relining. A total of 123 dentures from 70 partially edentulous patients were studied. Examination paste extruded from the tip of the 18‐G needle was applied to those denture surfaces contacting the alveolar crest. The denture was manually positioned with all clasps engaged on abutment teeth, and adaptation was assessed through paste distribution. Multiple logistic regression was used to analyse variables associated with diagnosing the need for a denture reline, producing odds ratios and 95% confidence intervals. The spread width was inversely proportional to the gap between the denture and mucosa. Regression analysis revealed statistically significant associations between the need for a denture reline and both the paste spread width and the duration of denture use. According to ROC curve analysis of the ‘reline’ and ‘non‐reline’ groups, the need for a denture reline was indicated at a paste spread width of 2·0 mm or less. At this 2·0‐mm threshold, the sensitivity was 85·1% and the specificity was 75·0%. The fit of removable denture bases was quantitatively evaluated by measuring the spread width of non‐setting pressure‐indicating paste extruded onto denture fit surfaces. The results suggest that the paste spread width is a useful parameter for discriminating the need for a denture reline.
Profits, Commercial Food Supplier Involvement, and School Vending Machine Snack Food Availability: Implications for Implementing the New Competitive Foods Rule
Authors: Terry‐McElrath Yvonne M. , Hood Nancy E. , Colabianchi Natalie , O'Malley Patrick M. , Johnston Lloyd D. 
Published: June 2014

ABSTRACTBACKGROUNDThe 2013‐2014 school year involved preparation for implementing the new US Department of Agriculture (USDA) competitive foods nutrition standards. An awareness of associations between commercial supplier involvement, food vending practices, and food vending item availability may assist schools in preparing for the new standards.METHODSAnalyses used 2007‐2012 questionnaire data from administrators of 814 middle and 801 high schools in the nationally representative Youth, Education, and Society study to examine prevalence of profit from and commercial involvement with vending machine food sales, and associations between such measures and food availability.RESULTSProfits for the school district were associated with decreased low‐nutrient, energy‐dense (LNED) food availability and increased fruit/vegetable availability. Profits for the school and use of company suppliers were associated with increased LNED availability; company suppliers also were associated with decreased fruit/vegetable availability. Supplier “say” in vending food selection was associated with increased LNED availability and decreased fruit/vegetable availability.CONCLUSIONSResults support (1) increased district involvement with school vending policies and practices, and (2) limited supplier “say” as to what items are made available in student‐accessed vending machines. Schools and districts should pay close attention to which food items replace vending machine LNED foods following implementation of the new nutrition standards.
Improving Pre‐Service Elementary Teachers' Self‐Reported Efficacy for Using the Professional Teacher Standards in Health Education
Authors: Clark Jeffrey K. , Clark Susan E. , Brey Rebecca A. 
Published: June 2014

ABSTRACTBACKGROUNDThe effectiveness of health education methods courses for pre‐service elementary teachers has not been assessed for improving the pre‐service elementary teacher's self‐efficacy for using the professional teacher standards in health education (PTSHE).METHODSA quasi‐experimental design was used to assess pre‐service elementary teachers' self‐efficacy toward using the PTSHE. Four institutions whose elementary education programs provide a health education methods course were recruited to participate in the study. Students were recruited to participate and they completed the Pre‐service Health Education National Standards Self‐efficacy (PHENSS) Scale at the beginning and end of the semester. Data were analyzed using SPSS (version 15) software.RESULTSA significant increase in the PHENSS Scale scores indicated that a 3‐credit health education methods course could improve the pre‐service elementary teacher's self‐efficacy to use the national standards in their teaching of health education. Further analysis indicated statistically significant improvement of the participants' PHENSS scores in 2 of the 7 standards.CONCLUSIONTeacher self‐efficacy can be a useful measure of the pre‐service elementary teachers' ability to use the national standards for health education. The design of the methods course may affect the PHENSS scores.
Optimizing Violence Prevention Programs: An Examination of Program Effectiveness Among Urban High School Students
Authors: Thompkins Amanda C. , Chauveron Lisa M. , Harel Ofer , Perkins Daniel F. 
Published: June 2014

ABSTRACTBACKGROUNDWhile demand for youth violence prevention programs increases, the ability of the school‐day schedule to accommodate their time requirements has diminished. Viable school‐based prevention programs must strike a balance between brevity and effectiveness. This article reports results from an effectiveness trial of a 12‐session curriculum‐based universal violence prevention program that promotes healthy conflict resolution skills among urban adolescents.METHODSUsing a review of program record data and a multisite quasi‐experimental study design, we examined the effectiveness of a New York City‐based violence prevention program entitled the Violence Prevention project (VPP) optimized to meet school needs. We analyzed survey data from 1112 9th‐ and 10th‐grade students in 13 New York City public high schools across 4 consecutive school years. Both participants and nonparticipants were surveyed.RESULTSReview of program record data indicated that the program was implemented with acceptable fidelity to the core component structure, and that participant responsiveness to the model was high. Multilevel modeling indicated that VPP participation was protective for academic self‐concept and promoted conflict resolution skills.CONCLUSIONSFindings indicate that semester‐long violence prevention programs optimized to meet the needs of a typical high school can be effective at promoting healthy conflict resolution skills in urban adolescents.