bluuebunny/crossref_metadata_2025_split huggingface dataset:
A global analysis on the view‐angle dependence of plane‐parallel oceanic liquid water cloud optical thickness using data synergy from MISR and MODIS
Authors: Liang Lusheng , Girolamo Larry Di 
Published: November 2012

AbstractWe examine the viewing zenith angle dependent bias (VZA bias) in warm cloud optical thickness (τ) retrieved from a plane‐parallel approach applied to fused Moderate Resolution Imaging Spectroradiometer (MODIS) and Multi‐angle Imaging SpectroRadiometer (MISR) data for the months of January and July between 2001 and 2008. The near‐simultaneous multiple view‐angle observations from MISR offers many advantages over previous τ‐VZA bias studies: 1) The analysis no longer requires seasonal and latitudinal cloud invariant assumptions, 2) consistent cloudy scene identification with VZA, 3) stratification of VZA‐bias with scene characteristics, and 4) a greater range of sun‐view geometries. Contrasting results between previous studies are resolved through careful consideration of the relative azimuth angle (RAZ) between sun and view. Relative to nadir‐retrieved τ, τ increases in both forward‐ and backscatter directions with higher value in backscatter directions for solar zenith angle (SZA) < ~40°. For SZA > ~40°, τ increases with increasing VZA in backscatter directions and strongly decreases in forward‐scatter directions. For the most oblique views, ~40–100% absolute monthly mean differences relative to nadir‐retrieved τ is common. This behavior is strongly tied to the sampled RAZ and explained based on three factors tied to the spatial heterogeneity of clouds. These factors also explain the behavior of the τ‐VZA bias when stratified by nadir‐retrieved τ and spatial heterogeneity, even in the thin‐cloud limit where sun‐glint effects are evident. We also observe an underestimation of τ relative to nadir in the rainbow‐scattering directions and attribute it to an overestimation of the cloud‐drop effective radius retrieved from MODIS due to cloud heterogeneity. There remains a need to quantify the bias in nadir‐retrieved τ as a function of SZA and spatial heterogeneity as a step toward providing bias correction over a wide range of sun‐view geometries.
Intrastream variability in solute transport: Hydrologic and geomorphic controls on solute retention
Authors: Patil Sopan , Covino Timothy P. , Packman Aaron I. , McGlynn Brian L. , Drummond Jennifer D. , Payn Robert A. , Schumer Rina 
Published: November 2012

AbstractHydrologic fluctuations and geomorphic heterogeneity are expected to produce substantial variability in solute transport within rivers. However, this variability has not been sufficiently explored due to the limited availability of solute injection data in most rivers. Here, we analyzed 81 tracer injection breakthrough curves (BTCs) along Stringer Creek, a 5.5 km2watershed in Montana. BTC measurements were obtained for three baseflow conditions at 27 reaches along a 2600 m stream channel. BTCs in upstream reaches (first 1400 m) had receding tails with shallow slopes, indicating high solute retention. Conversely, BTCs in downstream reaches (1400 to 2600 m) had receding tails with steeper slopes, indicating low solute retention relative to upstream reaches. Difference in BTC tails along the stream channel coincided with changes in channel morphology and bedrock geology. Specifically, channel slope increases from 5–6% (upstream) to 9% (downstream), channel sinuosity decreases from a maximum of 1.32 (upstream) to 1.02 (downstream), and the underlying bedrock changes from sandstone (upstream) to granite‐gneiss (downstream). Importantly, intrastream differences in BTC tails were distinctly observable only during the two lowest baseflow conditions. Spatial variability of BTC tail‐slopes was most sensitive to changes in local discharge at low flow, and to changes in channel sinuosity at high flow. BTC tail‐slopes varied temporally with local discharge and velocity at upstream reaches, but not at downstream reaches. These results suggest that local interactions between channel morphology and solute retention vary with hydrologic conditions, and that solute retention becomes more homogeneous at higher stream discharge.
Space Weather and Challenges for Modern Society
Authors: Brekke Pål , Steen Roger , Onsager Terry , Wintoft Peter , Olaussen Alf , Pirjola Risto , Stauning Peter , Sundelius Bengt , Ohnstad Trond , Marti Luis 
Published: November 2012

Key PointsMeeting summary after the OSLO TIEMS Space Weather Conference
Has the Time Come for Predictive Computer Modeling in CNS Drug Discovery and Development?
Authors: Geerts H , Spiros A , Roberts P , Carr R 
Published: November 2012

We discuss whether a new paradigm, quantitative systems pharmacology (QSP), based on computational neuroscience modeling combined with proper drug target engagement and pharmacology, human pathology, imaging studies, and calibration and validation using clinical studies in human subjects might improve the success rate of central nervous systems research and development (CNS R&D) projects. We suggest that an improved understanding of neuronal circuit interactions using a humanized computer‐based integration of physiology and pharmacology knowledge can substantially de‐risk new CNS projects.CPT: Pharmacometrics & Systems Pharmacology (2012) 1, e16; doi:10.1038/psp.2012.17; advance online publication 28 November 2012
Behavioral Management of Unilateral Vocal Fold Paralysis and Paresis
Authors: Schneider Sarah L. 
Published: November 2012

Purpose: In this article, I will summarize the process of selecting appropriate voice therapy candidates and relevant treatment techniques for patients with unilateral vocal fold paralysis or paresis.
Methods: I will present a review of the literature and pertinent clinical experience while laying out diagnostic tools, considerations for choosing voice therapy candidates, and specific therapy techniques that clinicians may employ. In addition, I highlight how these decisions are guided by a thorough behavioral diagnostic voice evaluation.
Results: There are a number of publications in the literature that discuss the role of voice therapy and the types of voice therapy techniques commonly used in treating vocal fold motion impairment. However, little efficacy data exist about the utility of voice therapy alone in this population.
Conclusions: Behavioral management of patients with vocal fold paralysis and paresis is widely accepted as part of the treatment process. With little efficacy data to support outcomes for specific voice therapy techniques alone with this patient population, we must continue to rely primarily on our clinical experience and outcomes from other populations to guide the therapeutic process.
Lumbago – Diagnostik
Authors: Artner Juraj 
Published: November 2012

ZusammenfassungKaum ein Symptom in der Humanmedizin ist so interdisziplinär vertreten und komplex wie der Rückenschmerz. Daher sind ein breites Fachwissen, interdisziplinäre differenzialdiagnostische Herangehensweise und adäquate strukturierte Abklärung und Patientenführung unumgänglich. Zur adäquaten Abklärung des Rückenschmerzes muss man zwischen akuten und chronischen Verläufen zu unterscheiden: Die Abklärung chronischer Schmerzen ist komplexer und erfolgt interdisziplinär. Unabhängig von seiner Fachrichtung sollte der Untersucher bei jedem Rückenschmerz eine Basisdiagnostik durchführen, bestehend aus Anamnese und Basisuntersuchung. Als Warnsignal („Red Flag“) gilt z.B. ein Sturz aus größerer Höhe, Tumoranamnese, B-Symptomatik, Ruheschmerz und neurologische Ausfälle. Als Provokationstests kommen u.a. der Iliosakral-Dehnugnstest, der Patrick-Fabere-Test und der Lasègue-Test infrage.
Ungewöhnlicher Leberabszess – Eine Mahlzeit mit schwerwiegenden Folgen
Authors: Eisner Friederike , Ladurner Ruth , Heuschmid Martin , Glatzle Jörg 
Published: November 2012

ZusammenfassungPyogene Leberabszesse äußern sich durch intermittierendes oder kontinuierliches Fieber und gegebenenfalls durch ihre verdrängende Wirkung. In der radiologischen Diagnostik stellen sich Leberabszesse als zystische Raumforderungen dar. Wichtige Ursachen sind z. B. eine aszendierende Cholangitis, septische Streuherde, parasitäre Abszesse oder Penetration. Der Krankheitsverlauf kann schleichend, aber auch akut und dramatisch sein. Prognosebestimmend ist die rasche Diagnose und Therapieeinleitung.
Double-periodic quasi-periodic graphene superlattice: non-Bragg band gap and electronic transport
Authors: Chen Xi , Zhao Pei-Liang , Zhu Qi-Biao 
Published: November 2012

Abstract
Electronic band gap and transport in quasi-periodic graphene superlattice (GSL) of double-periodic sequence are investigated. It is found that such quasi-periodic structure can possess a zero-averaged wave-number (zero-

) gap which is associated with an unusual Dirac point. Different from Bragg gap, the zero-

gap is less sensitive to the incidence angle, and robust against the lattice constants. The locations of Dirac point and multi-Dirac-points in the GSLs of various sequences are also compared. The control of electron transport over the zero-

band gap in GSLs may facilitate the development of many graphene-based electronics.
Automorphisms of Albert algebras and a conjecture of Tits and Weiss
Authors: Thakur Maneesh 
Published: November 2012

Let

k
k

be a field of characteristic different from 2 and 3. The main aim of this paper is to prove the Tits-Weiss conjecture for Albert division algebras over

k
k

which are pure first Tits constructions. The conjecture asserts that, for an Albert division algebra

A
A

over a field

k
k

, the structure group

S
t
r
(
A
)

Str(A)

is generated by

U
U

-operators and scalar multiplications. The conjecture derives its importance from its connections with algebraic groups and Tits buildings, particularly with Moufang polygons. It is known that

k
k

-forms of

E
8

E_8

with index

E

8
,
2

78

E^{78}_{8,2}

and anisotropic kernel a strict inner

k
k

-form of

E
6

E_6

correspond bijectively (via Moufang hexagons) to Albert division algebras over

k
k

. The Kneser-Tits problem for a form of

E
8

E_8

as above is equivalent to the Tits-Weiss conjecture (see Section 3). We provide a solution to the Kneser-Tits problem for

k
k

-forms of

E
8

E_8

corresponding to pure first Tits construction Albert division algebras. As an application, we prove that for the

k
k

-group

G
=

Aut

(
A
)
,

G
(
k
)

/

R
=
1

G=\textbf {Aut}(A),~G(k)/R=1

, where

A
A

is an Albert division algebra over

k
k

as above and

R
R

stands for

R
R

-equivalence in the sense of Manin.
Error patterns in age estimation and tooth readability assignment of grey seals (Halichoerus grypus): results from a transatlantic, image-based, blind-reading study using known-age animals
Authors: Frie Anne K. , Hammill Mike O. , Hauksson Erlingur , Lind Ylva , Lockyer Christina , Stenman Olavi , Svetocheva Olga 
Published: November 2012

AbstractFrie, A. K., Hammill, M. O., Hauksson, E., Lind, Y., Lockyer, C., Stenman, O., and Svetocheva, O. 2013. Error patterns in age estimation and tooth readability assignment of grey seals (Halichoerus grypus): results from a transatlantic, image-based, blind-reading study using known-age animals – ICES Journal of Marine Science, 70: 418–430. We analysed error patterns in a first interlaboratory grey seal (Halichoerus grypus) age-reading experiment. The experiment involved ten readers, who estimated age using images of cementum growth layers from teeth of 68 known-age seals (0–22 years). The percentages of correct estimates ranged from 32.4% to 60.3% among readers, and 89.3% of all errors were by ±1–2 years. Six readers showed increasing underageing with increasing seal age. An elevated risk of underestimation by 1 year occurred in teeth collected 0–5 months after breeding and was attributed to more frequent absence of a distinct growth layer for the new year and lack of information on months between the last birthday and the date of sample collection (plusmonths). For plusmonths 6–11, positive bias was predominant, suggesting that overestimation is the more common error when plusmonth information is available. Readers assigned readability scores to the tooth sections, and 79.1% of all ageing errors occurred in sections of low or intermediate readability. Excluding these sections would, however, also exclude 43.0% of all correct estimates. Neither levels of age estimation error nor predictive values of readability assignments were associated with reader experience levels. Analyses of image markings identified common errors in delineations of annual increment layers.
Spatial distribution of the stomach weights of juvenile anchovy (Engraulis encrasicolus L.) in the Bay of Biscay
Authors: Bachiller Eneko , Cotano Unai , Boyra Guillermo , Irigoien Xabier 
Published: November 2012

Abstract
Bachiller, E., Cotano, U., Boyra, G., and Irigoien, X. 2013. Spatial distribution of the stomach weights of juvenile anchovy (Engraulis encrasicolus L.) in the Bay of Biscay. – ICES Journal of Marine Science, 70: 362–378. Previous studies have shown that the survival of larval and juvenile anchovy off the continental shelf in the Bay of Biscay is not significantly different from that observed on the shelf, even though the food concentration is significantly higher on the shelf. In this paper we investigate the causes for the lack of relationship between food and survival for anchovy juvenile through analyses of feeding activity versus zooplankton distribution (in the transition from summer to fall from 2003 to 2010). The spatial distribution of the stomach weights of juvenile anchovy in relation to body size on and off the shelf revealed higher stomach fullness in areas off the shelf, where less zooplankton biomass was available. This result indicates that the food concentration is not always the main factor determining ingestion in fish. A situation of comparatively lesser prey abundance may provide better feeding conditions when combined with lower predation risk and lower light attenuation. In addition, the relatively heavier stomachs found in anchovies caught in years of higher recruitment indices suggest a large stomach content may be a symptom of good biological condition that may favour the winter survival of a larger fraction of the juvenile stock.
First Report of Hosta virus X Infecting Hosta Plants in China
Authors: Wei M. S. , Zhang Y. J. , Li G. F. , Ma J. , Li M. 
Published: November 2012

Hosta (Hosta spp.) plants showing leaf deformation, puckering, and ink-bleed symptoms were collected in July 2012 from a park at Dongcheng district, Beijing, China. Three out of six samples tested positive for Hosta virus X (HVX) by immunostrip and double-antibody sandwich (DAS)-ELISA with HVX-specific serological reagents from Agdia Inc. (Elkhart, IN, USA). Filamentous viral particles were trapped and observed from the infected hosta leaf sap by immuno-serological electron microscopy (ISEM) (antibodies from Agdia). To confirm HVX infection, three ELISA-positive samples were analyzed by reverse transcription-PCR assay, using virus-specific primers HVXf (5′-ATCCGTTATCTACAGGGGACCAG-3′) and HVXr (5′-TAAGTTAGTGGAACGGTTAGCCCGAT-3′) that amplified a 1,067-bp fragment including the coat protein (CP) coding region. The CP nucleotide sequence comparisons showed 99% to 100% homology among the three isolates named HVXBJ4, HVXBJ5, and HVXBJ6 (GenBank Accession No. JX535292, JX535293, and JX535294) and with the HVX sequences previously reported in GenBank. HVX has been reported from the United States, Korea, the Netherlands, Poland, France, the Czech Republic, and New Zealand (1,2). To our knowledge, this is the first report of HVX infecting hosta plants in China. As an ornamental and medicinal plant, hosta has been cultivated in China for more than 2,000 years. The presence of HVX in Beijing is a potential threat to the landscape in the city. HVX can be spread by vegetative propagation material or mechanical contact (3). Hence, to cultivate HVX-free hosta and restrict the movement of HVX-infected hosta is vitally important in the future. HVX has become economically important in the world more recently. Globalization of trade in hosta plants has increased the risk of movement of HVX. The national plant protection organization should establish effective quarantine strategy and the growers take proper planting measures to avoid further spreading of this virus. References: (1) S. Currier et al. Plant Dis. 80:1040, 1996. (2) M. H. Park et al. Arch. Virol. 148:2039, 2003. (3) K. H. Ryu et al. Acta Hortic. 722:91, 2006.
SIMULTANEOUS FZD4 AND LRP5 MUTATION IN AUTOSOMAL DOMINANT FAMILIAL EXUDATIVE VITREORETINOPATHY
Authors: Stiegel Evan , Say Emil A.T. , Carter B. Christian , Thomas Matthew J. , Shields Carol L. 
Published: November 2012

Purpose:
The purpose of this study was to report simultaneous mutations of FZD4 and LRP5 genes associated with autosomal dominant familial exudative vitreoretinopathy in members of one family.

Methods:
Case report.

Results:
A 16-month-old white boy with a 6-month history of leukocoria was referred for possible retinoblastoma. On examination, the left eye displayed extensive white vitreoretinal fibrosis filling the entire vitreous cavity up to the lens and with additional dystrophic calcification and iris neovascularization. The right eye showed temporal peripheral fibrovascular ridge. Fluorescein angiography showed 360° of peripheral nonperfusion with leakage from the fibrovascular ridge of the right eye and diffuse leakage from the massive vitreoretinal fibrosis and iris neovascularization of the left eye, consistent with familial exudative vitreoretinopathy. Laser photocoagulation of the avascular areas of the right eye was performed with disease stabilization. Clinical examination and genetic testing of the family members demonstrated that the proband and a male sibling had similar clinical findings and simultaneous mutations in the FZD4 and LRP5 genes. Both affected patients had normal bone mineral dual-energy X-ray absorptiometry.

Conclusion:
Familial exudative vitreoretinopathy is a retinal vascular disorder usually caused by a single mutation. Rarely, multiple simultaneous mutations can occur and, in this case, result in classic ophthalmic phenotypic and known risk for bone disorders.
MICROBUBBLE IN THE HOLE
Authors: Tatlipinar Sinan , Yenerel N. Melda 
Published: November 2012

Purpose:
To present a failed macular hole surgery with gas microbubble retention within the hole.

Methods:
A 68-year-old female patient with a Stage 2 macular hole underwent vitrectomy with removal of posterior hyaloid and 12% C3F8 gas injection. Because the macular hole was Stage 2 and posterior hyaloid was observed to be firmly attached over the macular area, no attempt was made for peeling of internal limiting membrane. Postoperatively, the patient was instructed to keep a facedown posture for 1 week. At 1-month visit, ophthalmoscopy revealed a tiny gas bubble filling the macular hole that failed to close.

Results:
The patient underwent a repeat vitrectomy in which internal limiting membrane was peeled, and the eye was filled with 20% SF6. At 2-week follow-up visit, the hole was observed to be closed.

Conclusion:
The reason for the macular hole nonclosure in this case may be the lack of internal limiting membrane peeling in the first operation. However, the authors believe that microbubble localized within the hole might have contributed to the failure.
Gastroesophageal Reflux Causing Sleep Interruptions in Infants
Authors: Machado Rodrigo , Woodley Frederick W. , Skaggs Beth , Di Lorenzo Carlo , Splaingard Mark , Mousa Hayat 
Published: November 2012

ABSTRACTBackground and Aim:Little is known about the relation between gastroesophageal reflux (GER) episodes and sleep interruptions in infants. The aim of the study was to evaluate the relationship between GER and the incidence of sleep interruptions in infants.Methods:Study patients included 24 infants (younger than 1 year) referred for multichannel intraluminal impedance and esophageal pH monitoring with simultaneous polysomnography. Exclusion criteria were a previous fundoplication and studies lasting <20 hours. Tests were clinically indicated to investigate suspicion of GER‐related apnea (17, 70.8%), stridor (6, 25%), noisy breathing (2, 8.3%), and cyanotic spells (1, 4.2%). Most patients presented with significant comorbidities (19, 79.2%).Results:The number of nonacid GER (NAGER) per hour was greater during sleep time than during daytime and awakening following sleep onset (median 0.27 vs 1.85 and 1.45, P < 0.01). A total of 1204 (range 7–86 per infant) arousals in 24 infants was detected, 165 (13.7%) that followed GER episodes, and 43 (3.6%) that preceded GER episodes. Seven patients presented with a positive symptom association probability for arousals; 5 were exclusively because of NAGER. A positive symptom association probability for awakenings was detected in 9 patients; 4 were because of NAGER, 4 were because of AGER, and 1 was because of both NAGER and GER. Patients with awakenings related to GER presented longer mean clearance time of AGER during sleep (165.5 vs 92.8 seconds, P = 0.03).Conclusions:GER was a frequent cause of interrupting sleep among our infant patients, and NAGER proved to be equally important as AGER for causing arousals and awakenings in infants.
Functional Phosphoproteomic Analysis Reveals That a Serine-62-Phosphorylated Isoform of Ethylene Response Factor110 Is Involved in Arabidopsis Bolting
Authors: Zhu Lin , Liu Dandan , Li Yaojun , Li Ning 
Published: November 2012

Abstract
Ethylene is a major plant hormone that plays an important role in regulating bolting, although the underlying molecular mechanism is not well understood. In this study, we report the novel finding that the serine-62 (Ser-62) phosphorylation of Ethylene Response Factor110 (ERF110) is involved in the regulation of bolting time. The gene expression and posttranslational modification (phosphorylation) of ERF110 were analyzed among ethylene-response mutants and ERF110 RNA-interfering knockout lines of Arabidopsis (Arabidopsis thaliana). Physiological and biochemical studies revealed that the Ser-62 phosphorylation of ERF110 was closely related to bolting time, that is, the ethylene-enhanced gene expression of ERF110 and the decreased Ser-62 phosphorylation of the ERF110 protein in Arabidopsis. The expression of a flowering homeotic APETALA1 gene was up-regulated by the Ser-62-phosphorylated isoform of the ERF110 transcription factor, which was necessary but not sufficient for normal bolting. The gene expression and phosphorylation of ERF110 were regulated by ethylene via both Ethylene-Insensitive2-dependent and -independent pathways, which constitute a dual-and-opposing mechanism of action for ethylene in the regulation of Arabidopsis bolting.