bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of Chemotherapy and Psychosocial Distress on Perceived Cognitive Disturbances in Asian Breast Cancer Patients
Authors: Cheung Yin Ting , Shwe Maung , Chui Wai Keung , Chay Wen Yee , Ang Soo Fan , Dent Rebecca Alexandra , Yap Yoon Sim , Lo Soo Kien , Ng Raymond Chee Hui , Chan Alexandre 
Published: December 2012

Background: There is conflicting evidence on the effect of chemotherapy and psychosocial distress on perceived cognitive changes in cancer patients. Objective: To compare the severity of perceived cognitive disturbance in Asian breast cancer patients receiving chemotherapy and those not receiving chemotherapy, and identify clinical characteristics associated with perceived cognitive disturbances. Methods: A cross-sectional, observational study was conducted at the largest cancer center in Singapore. Breast cancer patients receiving chemotherapy and not receiving chemotherapy completed the Functional Assessment of Cancer Therapy–Cognitive Function (FACT-Cog), European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (QLQ-C30), and Beck Anxiety Inventory to assess their perceived cognitive functioning, health-related quality of life, and anxiety, respectively. Multiple regression was conducted to delineate the factors associated with perceived cognitive disturbances. Results: A total of 85 breast cancer patients receiving chemotherapy and 81 not receiving chemotherapy were recruited. Chemotherapy patients experienced more fatigue (QLQ-C30 fatigue scores: 33.3 vs 22.2 points; p = 0.005) and moderate-to-severe anxiety (21.9% vs 8.6%; p = 0.002) compared to non-chemotherapy patients. Non-chemotherapy patients reported better perceived cognitive functioning than those who received chemotherapy (FACT-Cog scores: 124 vs 110 points, respectively; p < 0.001). Chemotherapy and endocrine therapy were strongly associated with perceived cognitive disturbances (p < 0.001 and 0.021, respectively). The interacting effect between anxiety and fatigue was moderately associated with perceived cognitive disturbances (β = -0.29; p = 0.037). Conclusions: Chemotherapy and endocrine treatment were associated with significant cognitive disturbances among Asian breast cancer patients. Psychosocial factors could be used to identify cancer patients who are more susceptible to cognitive disturbances in the clinical setting.
Adsorption isotherms in landfill leachate treatment using powdered activated carbon augmented sequencing batch reactor technique: Statistical analysis by response surface methodology
Authors: Aziz Shuokr Qarani , Aziz Dr. Hamidi Abdul , Yusoff Mohd Suffian , Mojiri Amin , Amr Salem S. Abu 
Published: December 2012

Abstract
Landfill leachate was treated using non-powdered activated carbon sequencing batch reactor (NPAC-SBR) and powdered activated carbon (PAC) augmented SBR (PAC-SBR) processesto examine Langmuir and Freundlichadsorption isothermsin the SBR technique.Response surface methodology (RSM) was used for the experimental design and statistical analysis.Based on the obtained results, the maximum adsorption capacitiesof ammonia nitrogen (NH3-N), color, and chemical oxygen demand (COD) for the Langmuir adsorption isotherm were 5.63 mg/g, 25.30 Pt.Co/g, and 13.21 mg/g,respectively, whereas for the Freundlichadsorption isotherm, thesewere 6 mg/g, 46.29Pt.Co/g, and 15.41 mg/g, respectively.Generally, Freundlich isotherm values for NH3-N, color, and COD were higher than Langmuir isotherm values.The NH3-N adsorption on PAC was lower than the color and COD adsorptions because a great part of NH3-Nwas biologically removed in the SBR process.Increasing aeration rate and contact times in the SBR processes increased the adsorption isotherms of NH3-N, color, and COD on PAC
Researchers and Small-scale Entrepreneurship
Authors: Garcia-Padilla Antonio 
Published: December 2012

AbstractFor decades, the Commonwealth of Puerto Rico relied on tax incentives to promote itself as a manufacturing hub for pharmaceutical and medical devices. These tax policies, coupled with a well-trained work force, turned Puerto Rico into one of the most vibrant manufacturing centers in the world. More than 40 companies operating in Puerto Rico created over 26,000 direct jobs and contributed another 50,000 indirect employments. Many of the top-selling prescription drugs in the market are manufactured in Puerto Rico. Lipitor, Viagra, Zocor, Zoloft, and many of the well-known blockbuster drugs came from the Island. As it encountered the tensions of the 21st Century, Puerto Rico realized that manufacturing alone cannot secure future economic success. Competition from the world’s emerging economy in Asia and Latin America was becoming stronger every day. China and India are capable of producing drugs with the same level of proficiency and at lower costs. Further, the pipeline for big blockbuster drugs is rapidly drying down. To maintain its role in the global health market, Puerto Rico realized that it must use its trained people not only to manufacture, but to research, design, develop and test products. Through clinical trials for emerging medicines, complex cell analysis and clinical diagnostic projects, Puerto Rico planned to play a role in creating the next generation of scientific discoveries; that it must move into the value line of its industrial base from manufacturing to drug development and testing. From the 1970’s on, in positioning itself as manufacturing hub, Puerto Rico relied on the fiscal autonomy that its current political status grants to the Island, and aggressively exempted from income and other taxes the profits that the pharmaceutical and medical devices companies generate in Puerto Rico. As the Island seeks to emigrate from manufacturing to research and development, the tax issues are different. Simply said, income tax incentives are not relevant for research centers, since research centers are cost centers, not profit centers. Puerto Rico then turned to a new experiment in tax policy: tax exemptions for the personal income of highly competitive researchers living and working in the Island. Thus, Puerto Rico moved to attract and retain in Puerto Rico competitive researchers and to create incentives for non-competitive scientists already living in Puerto Rico to move into more competitive projects. This article will explain the process, and the tax measures adopted by the Commonwealth Puerto Rico towards that end, and explore the potential developments in such policies as they are implemented in the years ahead.
Mode 4 of WTO's General Agreement on Trade in Services: Can it spur Cross-Border Labor Mobility from Developing Countries?
Authors: Dowlah Caf 
Published: December 2012

AbstractLiberalization of merchandize trade has brought forth extraordinary gains to world economy in recent decades. Available research, however, suggests that even greater benefits can result from the liberalization of global trade in services. Currently only about 20 percent of services are traded internationally although this sector accounts for more than half of global outputs, and exceeds 75 percent of GDP in high-income countries. Temporary movement of natural persons as service suppliers—as envisaged by GATS-Mode 4 of WTO—is one such services area which promises great benefits to both labor sending and receiving countries, but remains mired in a complex quagmire of trade and non-trade barriers as well as widespread misapprehensions. This paper argues that a basic convergence of economic interests seem to exist between the labor sending and receiving countries for liberalizing temporary movement of natural persons as service suppliers, and that, despite growing anti-immigration sentiments in developed countries, GATS-Mode 4 may be capable of spurring greater cross-border labor mobility.
A fetus with 19q13.11 microdeletion presenting with intrauterine growth restriction and multiple cystic kidneya
Authors: Lin Shin-Yu , Lee Chien-Nan , Chen Tai-Chang , Tu Mei-Ping , Lin Chiou-Ya , Chang Tung-Yao , Su Yi-Ning 
Published: December 2012

Abstract

Background: Constitutional deletions of chromosome 19q were rarely reported in the literature. The array-comparative genome hybridization (CGH) helps to identify four children with 19q13 microdeletion and the microdeletion of 19q13.11 is a recent emerging syndrome. We report one fetus with 19q12q13.12 deletion diagnosed prenatally and compare with five cases in the literature.

Case: The 29 year-old woman was at the 27th week of gestation. Prenatal ultrasound revealed severe intrauterine growth restriction and left side multiple cystic kidney with normal amniotic fluid index. Cordocentesis was performed for karyotyping and array CGH.

Results: The karyotype of the fetus was considered as normal male. The BAC array CGH identified one deletion at chromosome 19q12q13.12. The oligonucleotide array CGH further characterized the size of the breakpoint (chr19:35,116, 199-42,994,905). After counselling, the pregnancy was terminated at the 28th week of gestation. The aborted fetus had hypospadias and facial dysmorphisms.

Conclusions: Although a complete genotype-phenotype may not be established in these patients with 19q13 deletions, they shared some unique phenotypes and facial dysmorphisms. The clinician should keep in mind when anomalies are detected prenatally, array CGH may help to identify the etiology, which is critical for counselling.
Extracting Aluminum from Aluminum Alloys in AlCl3-NaCl Molten Salts
Authors: Xu Junli , Zhang Jing , Shi Zhongning 
Published: December 2012

AbstractExtracting aluminum from aluminum alloys in AlCl3-NaCl molten salts was investigated in this paper. The influences of experimental parameters such as electrolyte composition, cathodic current density and electrolysis time on the deposits morphology were discussed. The results show that the grain size of the deposits decreases with the increase of AlCl3 content in the electrolyte. Current density has a big effect on the morphology of the deposits. The particle size of deposits increases with the increase of current density, and dendritic morphology forms at high current density. High nucleation rates are achieved at high current densities above the limiting diffusion current density, and will result in a finer grain size. A non-dendritic deposit of aluminum was obtained at 170°C at 50 mA cm−2 cathodic current density for 1 h in the electrolyte having a 1.3 molar ratio of AlCl3/NaCl. The purity of the aluminum deposit is about 99.79% analyzed using inductively coupled plasma.
Photobiomodulation – The Chinese approaches and advances in clinical application/Photobiomodulation – Der Chinesische Ansatz und Fortschritte in der klinischen Anwendung
Authors: Liu Timon Cheng-Yi , Li Xing-Er , Liu Song-Hao 
Published: December 2012

AbstractPhotobiomodulation (PBM) is a biomedical treatment that uses monochromatic light or laser irradiation to stimulate or inhibit biological functions. Therapeutic applications of PBM are very common in China as the research on PBM and its therapeutic applications are very advanced. This paper reviews the literature in terms of the function-specific homeostasis, genetic redundancy and self-adaptation of the PBM phenomena and gives an overview of the clinical applications, such as laser acupuncture, intravascular low energy laser therapy, intranasal low intensity laser therapy and laser surgery, taking into consideration the approaches of functional medicine and Traditional Chinese Medicine.
Selbst und Schizophrenie
Authors: Fuchs Thomas 
Published: December 2012

Abstract
Current phenomenological approaches consider schizophrenia as a fundamental disturbance of the embodied self, or a disembodiment. This includes (1) a weakening of the basic sense of self, (2) a disruption of implicit bodily functioning, and (3) a disconnection from the intercorporality with others. As a result of this disembodiment, the pre-reflective, practical immersion of the self in the shared world is lost. Instead, the relationship of self and world is in constant need of reconstruction by deliberate efforts, leading to the growing perplexity and hyperreflexive ruminations that are found in schizophrenic patients. The paper distinguishes different levels of self-experience and relates it to the psychopathology of schizophrenia.
Vorhersagefehler und Gehirnverletzungen. Zwei-Faktoren-Theorien über Wahnvorstellungen
Authors: Radden Jennifer 
Published: December 2012

AbstractThis paper explores the two-factor theoretical model currently widely used to provide an explanatory analysis of the delusions that regularly accompany neurological disease or damage. The model hypothesizes a combination of an experiential factor – a strange or untoward experience – and a cognitive factor, such as an impairment of reasoning. The two-factor model has been devised formonothematicdelusions that are usually manifested in a single, implausible idea. These have to be distinguished from the more elaborated,polythematicdelusions that are found in psychiatry. Psychiatric delusions exceed neurological ones in frequency and, often, semantic complexity. This text offers a preliminary clarification of underlying assumptions about the breadth, terminology and presuppositions of two-factor theorizing, exploring its potential application to psychiatric delusions.
Kognitive Theorie, mentale Repräsentationen und Emotionen. Philosophie und therapeutische Praxis
Authors: Varga Somogy 
Published: December 2012

Abstract
Cognitive Theory (CT) is widely acknowledged framework used to understand the psychological processes involved in affective disorders and to conceptualize the adequate psychotherapy. The purpose of this paper is to assess the philosophical assumptions that CT rests upon. It will be argued that CT must be revised due to significant flaws in many of these philosophical assumptions. The last part of the paper will contain suggestions as to how these problems could be overcome in a manner that would secure philosophical coherence, while also providing an account that is better suited to explaining some of the cognitive, emotional and bodily manifestations of affective disorders.
Die goethische Methodologie des intuitiven Verstandes. Symposium zu: Eckart Förster: Die 25 Jahre der Philosophie
Authors: Wellbery David 
Published: December 2012

Abstract
Förster’s interpretation of the concept of intuitive understandung in Goethe is discussed with respect to the apprehension of transitions (Übergänge) in the phenomenon. Such intuition is both receptive (anschauend) und formative (bildend). Goethe’s theory of intuitive understanding proves to be an account of intentional content as a becoming-identical with the object as regard to its form.
Fatty Liver Increases the Association of Metabolic Syndrome With Diabetes and Atherosclerosis
Authors: Juárez-Rojas Juan G. , Medina-Urrutia Aida X. , Jorge-Galarza Esteban , González-Salazar Carmen , Kimura-Hayama Eric , Cardoso-Saldaña Guillermo , Posadas-Sánchez Rosalinda , Martínez-Alvarado Rocio , Posadas-Romero Carlos 
Published: December 2012

OBJECTIVE
To analyze the participation of fatty liver (FL) in the association of metabolic syndrome (MS) with type 2 diabetes and coronary artery calcification (CAC).

RESEARCH DESIGN AND METHODS
A total of 765 subjects (52% women) aged 30 to 75 years without clinical atherosclerosis were included in this study. MS was defined in accordance with the Adult Treatment Panel III (ATPIII) guidelines, while FL and CAC were identified by computed tomography.

RESULTS
There were increasing frequencies of type 2 diabetes and CAC in all three groups: control, MS without FL, and MS plus FL. Multivariable-adjusted logistic regression analyses showed that FL increased the association of MS with type 2 diabetes in both women [odds ratio 10.6 (95% CI 3.4–33.7)] and men [12.1 (4.1–36.1)]. In women, FL also increased the association of MS with CAC [2.34 (1.07–5.12)].

CONCLUSIONS
FL increases the association of MS with type 2 diabetes and subclinical atherosclerosis.
Effect of Hypoglycemic Agents on Ischemic Preconditioning in Patients With Type 2 Diabetes and Symptomatic Coronary Artery Disease
Authors: Rahmi Rosa Maria , Uchida Augusto Hiroshi , Rezende Paulo Cury , Lima Eduardo Gomes , Garzillo Cibele Larrosa , Favarato Desiderio , Strunz Celia M.C. , Takiuti Myrthes , Girardi Priscyla , Hueb Whady , Kalil Filho Roberto , Ramires José A.F. 
Published: December 2012

OBJECTIVE
To assess the effect of two hypoglycemic drugs on ischemic preconditioning (IPC) patients with type 2 diabetes and coronary artery disease (CAD).

RESEARCH DESIGN AND METHODS
We performed a prospective study of 96 consecutive patients allocated into two groups: 42 to group repaglinide (R) and 54 to group vildagliptin (V). All patients underwent two consecutive exercise tests (ET1 and ET2) in phase 1 without drugs. In phase 2, 1 day after ET1 and -2, 2 mg repaglinide three times daily or 50 mg vildagliptin twice daily was given orally to patients in the respective group for 6 days. On the seventh day, 60 min after 6 mg repaglinide or 100 mg vildagliptin, all patients underwent two consecutive exercise tests (ET3 and ET4).

RESULTS
In phase 1, IPC was demonstrated by improvement in the time to 1.0 mm ST-segment depression and rate pressure product (RPP). All patients developed ischemia in ET3; however, 83.3% of patients in group R experienced ischemia earlier in ET4, without significant improvement in RPP, indicating the cessation of IPC (P &lt; 0.0001). In group V, only 28% of patients demonstrated IPC cessation, with 72% still having the protective effect (P &lt; 0.0069).

CONCLUSIONS
Repaglinide eliminated myocardial IPC, probably by its effect on the KATP channel. Vildagliptin did not damage this protective mechanism in a relevant way in patients with type 2 diabetes and CAD, suggesting a good alternative treatment in this population.
LDOC-1 and PARP-1 mRNA expression in leukocytes of father and son with cutaneous malignant melanoma
Authors: Salemi Michele , Soma Pier , Condorelli Rosita , Recupero Domenico , Calogero Aldo 
Published: December 2012

Abstract
Apoptosis is central to the biology of cutaneous malignant melanoma (CMM). The leucine zipper, down regulated in cancer 1 (LDOC-1) gene, is known to be a regulator of the nuclear factor kappa B (NF-kB) through inhibition of the same NF-kB. The poly (ADP-ribose) polymerase-1 (PARP1) gene plays an important role for the efficient maintenance of genome integrity. PARP-1 protein is required for the apoptosis-inducing factor (AIF) translocation from the mitochondria to the nucleus. We report here two interesting cases of family melanoma, a father and son 84 and 40 years old, respectively. The histological evaluation of the lesions of both men revealed diffused superficial melanoma with epithelioid cells. We evaluated the differential expression of LDOC-1 and PARP-1 mRNA in peripheral blood leukocytes of both the father and son. We found that both LDOC-1 and PARP-1 genes were down-regulated in both patients compared with those of controls. These data suggest that low levels of expression of LDOC-1 and PARP-1 mRNA may be associated with familial melanoma.
Orthocomplemented difference lattices in association with generalized rings
Authors: Matoušek Milan , Pták Pavel 
Published: December 2012

Abstract
Orthocomplemented difference lattices (ODLs) are orthocomplemented lattices endowed with an additional operation of “abstract symmetric difference”. In studying ODLs as universal algebras or instances of quantum logics, several results have been obtained (see the references at the end of this paper where the explicite link with orthomodularity is discussed, too). Since the ODLs are “nearly Boolean”, a natural question arises whether there are “nearly Boolean rings” associated with ODLs. In this paper we find such an association — we introduce some difference ring-like algebras (the DRAs) that allow for a natural one-to-one correspondence with the ODLs. The DRAs are defined by only a few rather plausible axioms. The axioms guarantee, among others, that a DRA is a group and that the association with ODLs agrees, for the subrings of DRAs, with the famous Stone (Boolean ring) correspondence.
Spectral automorphisms in CB-effect algebras
Authors: Caragheorgheopol Dan 
Published: December 2012

Abstract
Spectral automorphisms have been introduced in [IVANOV, A.—CARAGHEORGHEOPOL, D.: Spectral automorphisms in quantum logics, Internat. J. Theoret. Phys. 49 (2010), 3146–3152]_in an attempt to construct, in the abstract framework of orthomodular lattices, an analogue of the spectral theory in Hilbert spaces. We generalize spectral automorphisms to the framework of effect algebras with compression bases and study their properties. Characterizations of spectral automorphisms as well as necessary conditions for an automorphism to be spectral are given. An example of a spectral automorphism on the standard effect algebra of a finite-dimensional Hilbert space is discussed and the consequences of spectrality of an automorphism for the unitary Hilbert space operator that generates it are shown.
The last section is devoted to spectral families of automorphisms and their properties, culminating with the formulation and proof of a Stone type theorem (in the sense of Stone’s theorem on strongly continuous one-parameter unitary groups — see, e.g. [REED, M.#x2014;SIMON, B.: Methods of Modern Mathematical Physics, Vol. I, Acad. Press, New York, 1975]) for a group of spectral automorphisms.
MacNeille completion of centers and centers of MacNeille completions of lattice effect algebras: Generic scheme behind
Authors: Niederle Josef , Paseka Jan 
Published: December 2012

Abstract
We present an example of a natural class of atomic Archimedean sharply dominating lattice effect algebras with non-bifull and atomic centers. Further, we extend and clarify known results about MacNeille completion of centers and centers of MacNeille completions of lattice effect algebras.
Efficient spatial privacy preserving scheme for sensor network
Authors: Debnath Ashmita , Singaravelu Pradheepkumar , Verma Shekhar 
Published: December 2012

Abstract
The privacy of sensitive events observed by a wireless sensor networks (WSN) needs to be protected. Adversaries with the knowledge of sensor deployment and network protocols can infer the location of a sensed event by monitoring the communication from the sensors even when the messages are encrypted. Encryption provides confidentiality; however, the context of the event can used to breach the privacy of sensed objects. An adversary can track the trajectory of a moving object or determine the location of the occurrence of a critical event to breach its privacy. In this paper, we propose ring signature to obfuscate the spatial information. Firstly, the extended region of location of an event of interest as estimated from a sensor communication is presented. Then, the increase in this region of spatial uncertainty due to the effect of ring signature is determined. We observe that ring signature can effectively enhance the region of location uncertainty of a sensed event. As the event of interest can be situated anywhere in the enhanced region of uncertainty, its privacy against local or global adversary is ensured. Both analytical and simulation results show that induced delay and throughput are insignificant with negligible impact on the performance of a WSN.
Integration of the environment in national accounting
Authors: Vandille Guy 
Published: December 2012

Résumé Les décisions en matière de politique économique doivent s’appuyer sur des données factuelles. Les comptes nationaux ont été conçus pour apporter une telle information, toutefois insuffisante pour couvrir l’ensemble des enjeux sociétaux. Les comptes satellites des comptes nationaux ont été créés pour mieux appréhender les réalités socio-environnementales. Cet article présente le cadre théorique qu’est le Système de Comptes Économiques de l’Environnement des Nations Unies (SEEA) pour la comptabilité économique de l’environnement. Il montre quelques résultats obtenus sur la base des comptes économiques de l’environnement de la Belgique. JEL : Q01