bluuebunny/crossref_metadata_2025_split huggingface dataset:
Age disparity in couples and the sexual and general health of the male partner
Authors: Sparano Clotilde , Rastrelli Giulia , Corona Giovanni , Vignozzi Linda , Vignoli Daniele , Maggi Mario 
Published: August 2024

AbstractIntroductionSeveral robust epidemiological studies suggest that men are often engaged in sexual relationships with younger women with a variable, age‐dependent age difference. However, the ageing process determines a significant worsening of the andrological status, which favors the onset of erectile dysfunction and hypogonadism.ObjectivesTo analyze the effects of differences in age between the partners [delta (Δ) age (M − F)] on patients referring to the Andrology Unit of Careggi University Hospital for male sexual dysfunction.Materials and methodsA monocentre cohort of 4055 male subjects was evaluated by SIEDY structured interview. The cross‐sectional analysis assessed the psychobiological and relational correlates. The rate of forthcoming major cardiovascular events (MACE) was investigated in the longitudinal analysis. All the models have been adjusted for age, education, lifestyle, and chronic disease score.Results∆ age (M–F) shows a stepwise increase, according to the increasing age bands of the male partner. ∆ age (M–F) was associated with a greater number of children, at the cost of more conflictual relationships within the family. The phenotype of these relationships is characterized by the report of a partner with a higher sexual desire and a higher ability to reach climax. Men seeking a younger partner show more often a histrionic personality (p = 0.023) and higher testosterone levels (p = 0.032). However, having a younger partner doesn't improve the ability to obtain a full erection. Kaplan–Maier analysis of a longitudinal subgroup of patients followed longitudinally (N = 1402) for 4.3 ± 2,59 years, showed that patients in the fourth quartile had a higher rate of forthcoming MACE versus those in the first quartile (p = 0.005).Discussion and conclusionIn subjects with sexual dysfunctions (as in the general population) age‐different relationships increase as a function of male ageing. A greater Δ age (M–F) is associated with specific men and relationship features and a higher risk of MACE.
Rural songs for COVID‐19 times? UK folk music's resurgent engagement with the countryside
Authors: Halfacree Keith 
Published: August 2024

AbstractThe COVID‐19 pandemic somewhat unexpectedly promoted resurgent interest in the attractions of rural places, not least associated with nature, in many countries for especially urban people. The paper argues that this link was very fecund for many within the broad UK ‘folk music’ community specifically. After introducing COVID‐19's pro‐rural turn, the paper gives a brief overview of now substantial music geography scholarship, paying particular attention to what has been studied in respect of folk music, not least its examination of the latter's problematic links to English identities. It argues that folk music's resurgent rural links call for attention. It then introduces how the rural‐folk music COVID‐19 experience worked at three non‐exclusive levels. First, there was rural influence on the music being produced. Second, some musicians were also personally impacted strongly by rural experiences, evident not solely through their music. Third, some musicians developed original rural initiatives that saw audience members also gaining direct rural inspiration, not just via the strong growth in internet‐facilitated connections but through direct in‐place encounters with the musicians in the rural. Each reading is illustrated by two brief case studies, with the rural‐folk combination becoming increasingly alive and more‐than‐representational. It is suggested in conclusion that there remains a strong ‘life’ to these rural‐folk music connections in less predominant COVID‐19 times.
Hidden formaldehyde in cosmetic products
Authors: Søgaard Rebekka , Poulsen Pia Brunn , Gelardi Rikke Munch , Geschke Susann , Schwensen Jakob Ferløv Baselius , Johansen Jeanne Duus 
Published: August 2024

AbstractBackgroundFormaldehyde is a common cause of contact allergy. Hidden formaldehyde, that is, formaldehyde in products without formaldehyde releasers, has previously been detected in cosmetic products.ObjectivesThe objective of this study was to investigate the content and causes of hidden formaldehyde in leave‐on cosmetic products.MethodsThe formaldehyde release from 142 cosmetic products, primarily creams, was analysed using the chromotropic acid (CA) method. The study included 130 products with no formaldehyde releasers on the ingredient list and 12 products with formaldehyde releasers. Products without formaldehyde releasers positive to CA, that is, with formaldehyde ≥2.5 ppm, were additionally analysed using high‐performance liquid chromatography (HPLC). Formaldehyde release from selected raw materials and packaging were also investigated.ResultsHidden formaldehyde was found in 23 of the 130 products (18%) without formaldehyde releasers on the ingredient list. The average formaldehyde content was 105 ppm (range: 0.5–507 ppm) in products with hidden formaldehyde and 355 ppm (range: 75–637 ppm) in eight products with formaldehyde releasers, selected for HPLC analysis. Impurities of formaldehyde in dihydroxyacetone may be a cause of hidden formaldehyde in self‐tanners. No clear pattern was found for the other products with hidden formaldehyde.ConclusionsChanges in regulation are needed to prevent allergic contact dermatitis from hidden formaldehyde in cosmetic products.
The effect of nurses' attitudes towards evidence‐based nursing on the level of compliance with isolation measures in nurses caring for liver transplant patients
Authors: Gürkan Kapıkıran , Okutan Şerafettin , Aktura Seher Çevik , Cici Remziye 
Published: August 2024

AbstractObjectiveLiver transplant recipients are at a high risk of infection during the first month. Therefore, it is crucial to implement isolation measures correctly to prevent the spread of nosocomial infections. Evidence‐based practices and proper implementation of isolation measures can significantly reduce morbidity and mortality. The study aimed to investigate the impact of nurses' attitudes towards evidence‐based nursing on their compliance with isolation measures.MethodsThis is a descriptive study conducted between October 2023 and January 2024, with the participation of 137 nurses working in the organ transplant clinics of a university hospital in Turkey. Data was collected using a participant introduction form, the attitudes towards evidence‐based nursing scale, and the compliance with isolation measures scale.ResultsThe mean total score for the scale of attitudes towards evidence‐based nursing among nurses was 55.95 ± 10.43 (15–75). Similarly, the mean total score for the scale of compliance with isolation measures was 71.44 ± 13.53 (18–90). Both scores were above the middle level. The study found a moderately significant positive correlation between attitudes towards evidence‐based nursing and compliance with isolation measures (r: 0.670, p: 0.000). The regression model showed that the attitude towards evidence‐based nursing explained 44.9% of the positivity towards isolation measures (R2 = 0.449).ConclusionsThe study found a positive correlation between nurses' positive attitudes towards evidence‐based nursing and their compliance with isolation precautions when caring for liver transplant patients. This highlights the significance of evidence‐based nursing in patient care and the importance of adhering to isolation measures to prevent nosocomial infections.
Twenty‐five emerging questions when detecting, understanding, and predicting future fish distributions in a changing climate
Authors: Kressler Molly M. , Hunt Georgina L. , Stroh Anna K. , Pinnegar John K. , Mcdowell Jonathan , Watson Joseph W. , Gomes Marcelo P. , Skóra Michał E. , Fenton Sam , Nash Richard D. M. , Vieira Rui , Rincón‐Díaz Martha Patricia 
Published: August 2024

AbstractThe 2023 Annual Symposium of the Fisheries Society of the British Isles hosted opportunities for researchers, scientists, and policy makers to reflect on the state of art of predicting fish distributions and consider the implications to the marine and aquatic environments of a changing climate. The outcome of one special interest group at the Symposium was a collection of questions, organized under five themes, which begin to capture the state of the field and identify priorities for research and management over the coming years. The five themes were Physiology, Mechanisms, Detect and Measure, Manage, and Wider Ecosystems. The questions, 25 of them, addressed concepts which remain poorly understood, are data deficient, and/or are likely to be impacted in measurable or profound ways by climate change. Moving from the first to the last theme, the questions expanded in the scope of their considerations, from specific processes within the individual to ecosystem‐wide impacts, but no one question is bigger than any other: each is important in detecting, understanding, and predicting fish distributions, and each will be impacted by an aspect of climate change. In this way, our questions, particularly those concerning unknown mechanisms and data deficiencies, aimed to offer a guide to other researchers, managers, and policy makers in the prioritization of future work as a changing climate is expected to have complex and disperse impacts on fish populations and distributions that will require a coordinated effort to address.
Mock juries, real trials: how to solve (some) problems with jury science
Authors: ROSS LEWIS 
Published: August 2024

AbstractJury science is fraught with difficulty. Since legal and institutional hurdles render it all but impossible to study live criminal jury deliberation, researchers make use of various indirect methods to evaluate jury performance. However, each of these methods is open to methodological criticism and, strikingly, some of the highest‐profile jury research programmes in recent years have reached opposing conclusions. Uncertainty about jury performance is an obstacle for legal reform; ongoing debate about the ‘justice gap’ for complainants of sexual offences has rendered these problems acute. This article proposes a way to advance the debate.
Fostering intergenerational harmony: Can good quality contact between older and younger employees reduce workplace conflict?
Authors: Drury Lisbeth , Fasbender Ulrike 
Published: August 2024

AbstractThis study examines how workplace conflict between multigenerational co‐workers arises and can be reduced. Utilizing social categorization and intergroup contact theories, we hypothesized that good quality contact between older and younger employees decreases task and relationship conflict by reducing perceived age discrimination (PAD), above and beyond trust as a typical social exchange mechanism prevalent in relationships between co‐workers. Furthermore, we predicted that task interdependence would exacerbate the relationships between PAD with task and relationship conflict. We applied structural equation modelling using a sample of 567 older and younger British employees to test our hypotheses while controlling for trust as an alternative mechanism. In line with our predictions, we found that good quality contact between older and younger employees reduced employees' PAD, which in turn reduced task conflict and relationship conflict (above and beyond trust as a control mechanism). The indirect effects of intergroup contact on workplace conflict via PAD were further enhanced when cross‐age co‐workers were highly interdependent in conducting their work tasks. Our findings suggest that organizations should create practices to improve cross‐age contact in the workplace.
Displaying ingredients on healthy snack packaging: A study on visual attention, choice, and purchase intention
Authors: Retamosa Marta , Aliagas Irene , Millán Angel 
Published: August 2024

AbstractThe key packaging element in healthy snacks is the ingredient. This research highlights the use of eye tracking by companies to achieve greater effectiveness on the consumer's attention. Three healthy snacks were presented to analyze whether there are differences in their attention, choice, and purchase intention according to the type of ingredient. An eye‐tracking device and a questionnaire were applied and the results showed that the central area of the packaging of healthy snacks in which the ingredients are shown attracts more attention. Positive relationships between the choice of a snack and the intention to purchase it, and between the total fixation duration and the choice of a product were found. Food products with more hedonic components (flavor, e.g., chocolate) were much more visually attractive and captured more attention. At the same time, those products with less desirable or palatable ingredients were chosen less.Practical ApplicationsThis research provides insights into how packaging design influences consumer perceptions of healthy snacks. Food packaging plays a crucial role in capturing consumer attention and communicating information that affects their purchasing decisions. In this context, understanding how consumers direct their attention and what information they consider when evaluating products is essential for professionals in fields such as food science, marketing and graphic design, where the use of eye‐tracking devices is key. Furthermore, resistance to less desirable or unfamiliar products hinders purchase intent, suggesting the need to improve their appeal and communicate their health benefits. This study confirms that, when designing the packaging of healthy snacks, it is necessary to focus more on the central part of the packaging, which should show the composition and its appearance with a real image of it.
A comparative analysis of nurses' reported number of patients and perceived appropriate number of patients in integrated nursing care services
Authors: Kwon Hyunjeong , Kim Jinhyun 
Published: August 2024

AbstractThis study aimed to compare the number of assigned and appropriate patients per nurse in integrated nursing care service wards and analyze factors associated with the gap. For this cross‐sectional secondary analysis, data were collected from surveys of 2312 nurses and institutional data from their affiliated 106 hospitals in Korea. We used the Wilcoxon signed‐rank test and t‐test to compare the number of patients assigned to nurses with the number they considered appropriate. We used ratio analysis for measuring the gap between these numbers, and robust regression to evaluate the factors affecting this gap. The results found an average gap of 1.45, indicating that the reported number of assigned patients per nurse was 1.45 times higher than the appropriate number. Gender, employment type, wage satisfaction, workload, overtime work, and hospital level of care were identified as factors associated with the gap. Findings suggest that the current nurse staffing standard should be revised to consider nurses' professional judgments of appropriate staffing levels and adopt policies that reduce nurses' workload.
A prospective study evaluating the adhesive tape impression for the diagnosis of dermatophytosis in dogs and cats
Authors: Ludwig Courtney B. , Tyler Sophie A. , Lima Tatiana , Vogelnest Linda J. 
Published: August 2024

AbstractBackgroundPotential contagion and zoonotic risk make rapid diagnosis of dermatophytosis important amongst companion animals.Hypothesis/ObjectivesTo compare the adhesive tape impression (ATI), trichogram, Wood's lamp (WL) examination and fungal culture for diagnosis of dermatophytosis, and the ATI and trichogram for ease of use.AnimalsFive dogs and 15 cats with consistent lesions, history and at least two positive dermatophyte test results.Materials and MethodsAfter WL examination, one representative lesion per patient was sampled for ATI, trichogram and fungal culture. Microscopic detection of fungal elements on ATI and trichogram were objectively and subjectively compared. The ability of all tests to correctly detect dermatophytosis, and the ability of ATI and trichogram to detect fungal elements in >20 high‐powered fields (HPF) were compared using Fisher's exact tests.ResultsATI, trichogram, fungal culture and WL were positive in 100% (20 of 20), 90% (18 of 20), 95% (19 of 20) and 65% (13 of 20) of patients, respectively, with a significant difference between WL and ATI (p = 0.0499). Fungal culture revealed Microsporum. canis (n = 16), Nannizzia gypsea (n = 1), Trichophyton mentagrophytes (n = 1) and T. rubrum (n = 1). Fungal elements were detected in >20 HPF more frequently with ATI (18 of 20) than trichogram (11 of 20) (p = 0.017), and detection required careful scanning to distinguish from background debris more often with trichogram. Fungal elements were located with neutrophil clusters and keratinocyte rafts in addition to abnormal hair fragments more frequently on ATI.Conclusions and Clinical RelevanceATI had the highest ability to correctly diagnose dermatophytosis, and increased ease of detecting fungal elements compared to trichogram.
Chemical stability and in vitro antimicrobial efficacy of diluted silver sulfadiazine powder and cream over a six‐month period
Authors: Lopresto Christopher M. , Palmeiro Brian S. , Cole Stephen D. , Xu Xin , Dietrich Jaclyn , Stefanovski Darko 
Published: August 2024

AbstractBackgroundSilver sulfadiazine (SSD) is commonly formulated into otic preparations to treat otitis externa, although evidence of stability and antimicrobial efficacy with long‐term storage is lacking.ObjectivesTo evaluate the effect of storage time on chemical stability and in vitro antimicrobial activity of SSD diluted in sterile water, including two 1% suspensions using SSD pharmaceutical‐grade powder stored at room temperature (RT) in plastic or sterile glass bottles, and a 1:9 dilution using prescription SSD 1% cream stored at RT in a sterile glass bottle.Materials and MethodsLiquid chromatography–tandem mass spectrometry (LC–MS/MS) assessed chemical stability. Trimethoprim/sulfamethoxazole‐susceptible and trimethoprim/sulfamethoxazole‐resistant strains of Staphylococcus pseudintermedius (SP), meticillin‐resistant (MR) SP, S. schleiferi (SS), MRSS, Pseudomonas aeruginosa, Proteus mirabilis and Escherichia coli evaluated by 24 h time–kill analysis assessed in vitro antimicrobial efficacy. Each assessment was performed at zero, one, three and six months of storage.ResultsLC–MS/MS showed no significant change in concentration over time for any suspension. When adjusted for time and species/strain, all SSD suspensions showed significant reductions in colony forming units (cfu)/mL at 24 h (p < 0.001). Including all suspensions, a bactericidal effect (minimum 3‐log cfu/mL reduction at 24 h) occurred against 94% of total isolates, with failure against 33 of 552 isolates (6%). Bactericidal failure was more likely with the cream‐based suspension (p < 0.05) and at six months (p < 0.01).Conclusions and Clinical RelevancePowder‐based and cream‐based SSD/sterile water suspensions showed no significant change in concentration and demonstrated in vitro antimicrobial activity for six months. Bactericidal failure was more likely with the cream‐based suspension and after six months of storage.
Delivery of
Yersinia pestis
antigens via
Escherichia coli
outer membrane vesicles offered improved protection against plague
Authors: Tong Zehui , Zhang Xiangting , Guo Xiao , Wu Gengshan , Cao Shiyang , Zhang Yuan , Meng Xiangze , Wang Tong , Wang Yiqian , Song Yajun , Yang Ruifu , Du Zongmin 
Published: August 2024

ABSTRACT

Outer membrane vesicles (OMVs) from Gram-negative bacteria can be used as a vaccine platform to deliver heterologous antigens. Here, the major protective antigens of
Yersinia pestis,
F1 and LcrV, were fused either with the leader sequence or the transmembrane domain of the outer membrane protein A (OmpA), resulting in chimeric proteins OmpA-ls-F1V and OmpA
46-159
-F1V, respectively. We show that OmpA-ls-F1V and OmpA
46-159
-F1V can be successfully delivered into the lumen and membrane of the OMVs of
Escherichia coli,
respectively. Mutation of
ompA
but not
tolR
in
E. coli
enhanced the delivery efficiency of OmpA-ls-F1V into OMVs. The OmpA-ls-F1V protein comprises up to 20% of the total protein in OMVs derived from the
ompA
mutant (OMV
dA
-ALS-F1V), a proportion significantly higher than the 1% observed for OmpA
46-159
-F1V in OMVs produced by an
ompA
mutant that expresses OmpA46-159-F1V, referred to as OMV
dA
-LATM5-F1V. Intramuscular (
i.m
.) immunization of mice with OMV
dA
-ALS-F1V induced significantly higher levels of serum anti-LcrV and anti-F1 IgG, and provided higher efficacy in protection against subcutaneous (
s.c.
)
Y. pestis
infection compared to OMV
dA
-LATM5-F1V and the purified recombinant F1V (rF1V) protein adsorbed to aluminum hydroxide. The three-dose
i.m
. immunization with OMV
dA
-ALS-F1V, administered at 14-day intervals, provides complete protection to mice against
s.c.
infection with 130 LD
50
of
Y. pestis
201 and conferred 80% against intranasal (
i.n
.) challenge with 11.4 LD
50
of
Y. pestis
201. Taken together, our findings indicate that the engineered OMVs containing F1V fused with the leader sequence of OmpA provide significantly higher protection than rF1V against both
s.c
. and
i.n
. infection of
Y. pestis
and more balanced Th1/Th2 responses.

IMPORTANCE

The two major protective antigens of
Y. pestis
, LcrV and F1, have demonstrated the ability to elicit systemic and local mucosal immune responses as subunit vaccines. However, these vaccines have failed to provide adequate protection against pneumonic plague in African green monkeys. Here,
Y. pestis
F1 and LcrV antigens were successfully incorporated into the lumen and the surface of the outer membrane vesicles (OMVs) of
E. coli
by fusion either with the leader sequence or the transmembrane domain of OmpA. We compared the humoral immune response elicited by these OMV formulations and their protective efficacy in mice against
Y. pestis
. Our results demonstrate that the plague OMV vaccine candidates can induce robust protective immunity against both
s.c
. and
i.n. Y. pestis
infections, surpassing the effectiveness of rF1V. In addition, immunization with OMVs generated a relatively balanced Th1/Th2 immune response compared to rF1V immunization. These findings underscore the potential of OMVs-based plague vaccines for further development.