bluuebunny/crossref_metadata_2025_split huggingface dataset:
1477 – Role Of Rotigotine, a Dopaminergic Modulator, In The Management Of Pharmacoresistant Depressed Patients
Authors: Pompei F. , Di Lorenzo C. , Penna L. , Gentili F. , De Filippis S. 
Published: July 2013

IntroductionPharmacoresistant depression is a challenging clinical condition faced daily by psychiatrists. Although several strategies have been tried to optimize the outcome of this condition, depressive symptoms management remains difficult. Serotonin is regarded as the target neurotransmitter of mood regulation while other monoamines are considered as secondary characters in symptoms management although their role has not been fully explored.ObjectivesVerify the role of dopaminergic modulation in management of pharmacoresistant depression.AimsAim of our study is to evaluate the role of a dopaminergic treatment in pharmacoresistant depression management by administration of transdermal rotigotine.MethodsPharmacoresistant depressed patients, with a stabilized antidepressant treatment and in lack of symptomatic improvement in last six weeks, underwent a clinical trial with transdermal rotigotine, up to 4 mg/day. Symptoms were evaluated at the beginning of treatment and after one month by three validated scales: Hamilton Depression Scale (HAMD), Hamilton Anxiety Scale (HAMA) and Global Assessment of Functioning (GAF).ResultsTen patients (9 F / 1 M; mean age 48,1 yrs) fulfilled inclusion criteria in the roll-in period. The mean scores before rotigotine treatment were: 22.80±5.8 for HAMD, 25.9±4.9 for HAMA and 41.4±11.62 for GAF. After one month of treatment with rotigotine, scores respectively changed in 11.3±3.3 (t=5.76; p< 0.001), 17.2±1.5 (t=6.37; p< 0.001) and 58.3±4.7 (t=-4.24; p=0.002).ConclusionsDopaminergic modulation achieved by rotigotine improved mood, motor and anxiety and global functioning scores, in lack of any side effect. In particular, transdermal administration avoided drug plasmatic peacks related to side effects
1484 – Could Emotional Awareness Influence Drinking Outcomes In An Alcohol Dependent Population?
Authors: Raucher-Chéné D. , Cuervo-Lombard C.-V. , Kaladjian A. 
Published: July 2013

IntroductionAlexithymia has been studied in several addictive disorders with a special interest in alcohol dependence (Thorberg et al., 2009; Taieb et al., 2002). Nevertheless, recent studies failed to demonstrate the relationship with drinking outcomes (de Haan et al., 2012; Stasiewicz et al., 2012). Evaluation of emotional awareness in these populations could be added to specify the deficits of emotions’ differentiation and to understand the mechanisms underlying the maintenance of abstinence (Bochand & Nandrino, 2010; Carton et al., 2010).AimsWe intend to evaluate short and long-term abstinent alcohol dependent subjects in a dimensional approach for alexithymia and emotional awareness, expecting relationship with drinking outcomes.MethodsThirty-two abstinent alcohol dependent participants and 28 matched controls were included. The two groups were assessed for anxiety (STAI state and trait) and depression (BDI-II). Alexithymia (TAS 20) and emotional awareness (Emotional Self-Awareness Questionnaire; ESQ) were also evaluated. The severity of alcohol dependence was specified with Alcohol Dependence Severity scale.ResultsAlexithymia was significantly higher in the group of alcohol dependent participants (50.1 vs 45.1; p=0.049). Within the alcohol dependent group, ESQ was negatively correlated to the severity of alcohol dependence (r=-0.29; p=0.028) with subscales “social awareness” and “social skills” negatively correlated to the duration of abstinence (r=-0.37; p=0.03 and r=- 0.38; p=0.01, respectively).ConclusionsAlexithymia is significantly higher in the alcohol dependent group, compared to the control group, but within this group, evaluation of emotional awareness may become more interesting to evaluate the characteristics of alcohol dependent subjects and predict their drinking outcomes
1489 – Study On Dream Contents In Patients With Suicidal Attempts In Poisening Section Of Afzalipor Hospital And Compaired With Control Group
Authors: Mehdizadeh Zare Anari A. , Ghaffarinejad A. , Najmaee S. 
Published: July 2013

ObjectiveOne of important issue in psychodynamical healt is suicide.more than 60% of people who act complete suicide,suffered from psychological illness.One of important factor for psychodinamic resolutation of this attempt is the survey of their dream.Dream can be used as a tool for deliberation of suicidal intention.refering to this fact that a forth of people who have suicide attempt, may have another attempt within the next year,so we desided to check validity of dream in this kind of people in order to reach an objective relationship to determine peril of a further attempt.MethodsIn this study 50 subject of people who have suicide attempt thruogh taking pill and 50 case were selected as the control group.The people studied were asked to record their dream,then these dream were codified on the basis of Hall van de castle method.Data analyzed with and ANOVA with SPSS17.ResultsThis study showed that a dead character contents(pv=0/00) and non-speaking activities(pv=0/045)in dreams are more in people who have suicided, and if friendship validity exists the dremer is the recivier of friendship(pv=0/026) and the setting usually are undetermined(pv=0/041).ConclusionThis result indicate that present of death content and non-speaking activity in dream of persons who get psychological health care can be an Alarm for suicidality in these persents.
1490 – Transsexualism And Personality, Study About 14 Cases With Structured Assessment
Authors: Gaudeau V. 
Published: July 2013

IntroductionTranssexualism is a rare condition, characterized by permanent conviction of belonging to opposite sex, leading to a request for hormono-surgical sex reassignment.Objectives and aims of the studyThe personality of transsexual patient is a matter of debate: most psychoanalysts postulate a severe personality disorder, while STOLLER's and biological hypothesis argue for of the absence of specific disturbance.MethodsFourteen transsexuals patients (9 men and 5 women), referred to the specialized multidisciplinary team of Nantes University hospital were included. All received hormone therapy, 5 patients underwent surgery. The MMPI-2 and SCID-II were used as standardized tools to assess personality.ResultsUsing the SCID-II, frequency of personality disorders was 14.29%, showing no statistical difference compared to the general population (10%). The MMPI-2 mean T score was close to the general population 50. Moreover, man versus woman transsexuals have a degree of psychopathology significantly higher than woman versus man transsexuals. Operated versus non-operated patients showed no significant differences in the various tests.ConclusionOur results tend to relativize the unique psychopathological determinism of transsexualism, and seem to strengthen the hypothesis of biological factors involved in this problem.The prognosis is more favorable for woman versus man transsexuals.
1497 – Men Committing Spousal Homicides
Authors: Delbreil A. , Voyer M. , Lebeau M. , Sapanet M. , Senon J.-L. 
Published: July 2013

IntroductionThe spousal homicide is committed on a partner or ex-partner of intimate life whatever the stature of this one. In France, it represents about 20% of total homicide. Its multifactorial origin makes its spotting complex.ObjectiveThe aim of this study is to determine predictive factors of acting out, by analyzing sociodemographical, psychopathological and criminological features of men committing spousal homicide.MethodIt is a descriptive and retrospective study of 37 spousal homicides (or attempts of homicides) files judged between 1999 and 2010 by the Court of Appael of Poitiers. An important number of variables concerning the perpetrators, the victims and the facts have been searched. Then, they have been sorted to establish profiles.ResultsMen stand for 88% of spousal homicides perpetrators. Most of them are impulsive (80,4%), have a judicial (64,8%) and domestic violence (70,3%) previous history. Half drinks excessively. The acting out is often motivated by the couple breaking up (64,8%). Homicide is frequently committed with an excessive violence (54%). Before the crime, about half of the perpetrators had expressed death or suicide threats.ConclusionOur study showed that spousal homicide is an unpremeditated act committed by men, facing the difficulty to accept their partner leaving. This crime is often linked to domestic violence and chronical alcoholism. Emphasizing these profiles allow to offer better-aimed prevention measures.
1498 – Patient Characteristics, Service Usage And Continuity-of-care Over One Year Of a Representative Cohort Of People With a Diagnosis Of Severe Mental Illness Across England
Authors: Reilly S. , Planner C. , Hann R. , Reeves D. , Nazareth I. , Lester H. 
Published: July 2013

AimsThis presentation describes and analyses patient characteristics and service usage over one year of a cohort of people with a diagnosis of severe mental illness across England, including contacts with primary and secondary care and continuity- of-care.MethodsData were collected from primary care patient notes (n=1150) by trained nurses from 64 practices in England, covering all service contacts from 1st April 2008 to 31st March 2009.ResultsThe estimated national rate of patients seen only in primary care was 31.1% and rates of schizophrenia and bipolar disorder were 56.8% and 37.9%. Patients had 7,961 consultations within primary care and 1,993 contacts with mental health services (20% of the total). Of those seen in secondary care, 61% had at most two secondary care contacts recorded in primary care notes. Median consultation rates with GPs were lower than have been reported for previous years and were only slightly above the general population. Relational continuity in primary care was poor for 21% of patients (Modified Modified Continuity Index =< 0.5), and for almost a third of new referrals to mental health services the primary care record contained no information on the referral outcome.ConclusionsPrimary care is centrally involved in the care of people with serious mental illness, but primary care and cross- boundary continuity is poor for a substantial proportion. Research is needed to determine the impact of poor continuity on patient outcomes, and above all, the impact of new collaborative ways of working at the primary/secondary care interface
1499 – Neurodynamic Patterns Of Sleep Disturbances Related To Posttraumatic Stress Disorder In War Veterans
Authors: Pudikov I. , Smirnova D. 
Published: July 2013

Sleep disturbances are important features of posttraumatic stress disorder (PTSD), however, data characterizing PTSD sleep phenomena are limited. Detailed clinical description of sleep function and its study with the use of modern instrumental methods is important for timely and differential diagnosis of mental disorders in PTSD patients.21 war veterans fighting in “hot spots were observed during treatment in the specialized department of psychological rehabilitation, Samara Regional Clinical Hospital for War Veterans. After clinical interview the overnight polysomnography “Sagura-2000” (PSG) was performed.Sleep disorders in PTSD patients are characterized by the complex of subjective, clinical and neurophysiological symptoms:1.Superficial sleep (restless, lack of deep sleep);2.Increased motor activity during sleep (number of activations of the paradoxical phase of sleep to those of deep sleep);3.Nightmares;4.Specific (defensive) movements during sleep;5.Frequent nocturnal awakening (increased number and duration of awakenings);6.The excess of REM sleep. PSG identified the most frequently related nightmares neurodynamic phenomena:1.Deficiency of the deep sleep (stages 3 and 4 NREM);2.Up to 70% of the time NREM takes stage 2 sleep;3.The increase in motor and EEG activations;4.The number of activations of the REM than those of NREM;5.The increase in total REM sleep time;6.Increasing episodes of REM sleep.Further studies are required to clarify polysomnographic sleep changes, in particular, role of REM sleep dysregulation and treatment of sleep disorders in PTSD.Study was supported by Russian Humanitarian Scientific Foundation (???? 12-36-01155)
1501 – Early Effects Of Agomelatine On Self-referential Processing In Acute Depressed Patients: a Fmri Study
Authors: Fossati P. , Jabourian M. , Laredo J. , Allailli N. , Lehericy S. , Delaveau P. 
Published: July 2013

Increased Self-focus, the tendency to excessively appraise stimuli as strongly related to oneself, is a core feature of major depression. In major depressive disorder increased self-focus is associated with abnormal dorsal and ventral medial prefrontal activity as well as increased dorsolateral prefrontal activity.ObjectiveAlthough Lemogne et al, 2010 suggested that Medial Prefrontal Activity does not change after reduction of depressive symptoms, sensitivity of brain regions involved in self-referential processing to antidepressant is unknown. The main goal here was to assess with fMRI early effects of agomelatine, on self-referential processing in depressed patients.Methods25 acute depressed patients and 14 healthy controls were scanned before and after 7 days treatment, while performing self-referential processing task using emotional pictures. Patients were randomized to agomelatine 25mg/day (n=13) or placebo (n=12), healthy controls received placebo. Subjects were asked to evaluate pictures according to different conditions: Self (Does the picture relate to you?); General (Is the picture positive or negative?). Depression was assessed with Hamilton Scale.ResultsDepressed patients compared to controls at baseline showed hyperactivity in dorsolateral prefrontal cortex, dorsal anterior cingulate and ventrolateral prefrontal cortex (VLPFC). After 7 days treatment, Agomelatine, compared to placebo, normalized the hyperactivity of VLPFC to healthy volunteers’ level.ConclusionAgomelatine targets specific brain structures, namely VLPFC, involved in automatic regulation of emotion during self-referential processing. These changes in brain activity at day 7 could contribute to the early clinical effects of agomelatine, suggesting an early set up of the brain for long term response and remission of depression.
1507 – Consequences Of The Choice To Specialize In Psychiatry
Authors: Szczegielniak A. , Skowronek A. , Skowronek R. , Wydra K. , Krysta K. , Krupka-Matuszczyk I. 
Published: July 2013

IntroductionProviding of mental health service is the main task of every country. Its implementation obviously depends on the number of professionally active psychiatrists. So the issues of a great importance for current psychiatry are determinants and consequences of the decision of specialization in this medical domain.ObjectivesThe aim of our work was, most of all, the assessment of motives of the choice of specialization in psychiatry from the perspective of physicians-practitioners.MethodsIn order to do it, we prepared an original questionnaire, which contained 22 questions (some of them were of multiple choice) concerned with, i. e. sociodemographical and professional aspects. The study group was created from 132 psychiatrists (including 33 men), participating in international scientific-training conference in Wisla in 2011. Average age was 43 years (SD=9.7), and seniority in psychiatry - 15 years (SD=9.8). The obtained results were statistically analyzed using Statistica 8.0. Detailed results of our analysis will be presented during conference.ResultsThe results of our questionnaire may be used to improve the image of psychiatry as attractive path of professional career (almost 95% of questionnaired physicians do not regret their decision!).ConclusionsThe results may also become an essential argument during the discussion about current problems in psychiatry, for example problem of occupational burnout, and possibilities of their solution.
1509 – Methadon Therapy, Damage Reduction In a Wider Social Context
Authors: Macic A. , Stjepcevic A. , Cetkovic A. 
Published: July 2013

Two years ago the second methadon center was opened in Montenegro.The goal of this treatise is to show all aspects of ‘damage reduction’, more precisely, of the benefit a methadon center offers to its environment. Under the term’damage reduction; are meant medical aspects [smaller number of cases of hepatitis C and HIV] as well as the influence on the social functioning of an individual. This work will show the positive influence of the methadon center on the community in general, beginning with impressive reduction of the number of new heroin addicts on annual basis to the influence on the total heroin circulation on the street and reduction of criminal acts committed by heroin addicts. Better results are noticed in smaller communities, so the work considers optimal number of inhabitants that one center can cover to achieve the best effects in this sense.In conclusion, the net of methadon centers ought to be spread, not only for the benefit of drug addicts and their families, but for the welfare of the entire society, as well.
1511 – Interface Between Child And Adult Mental Health Services. What Can We Do To Improve The Gap?
Authors: Moscoso A. , Jovanovic N. 
Published: July 2013

BackgroundTransition from adolescent to adult mental health services is extremely important since most mental illnesses start in late adolescence. Although often discussed, this issue is rarely studied.AimThe aim of this study is to gather information of how transition from adolescent to adult mental health services is yielded across Europe.MethodologyThe study was conducted during the EPA and the IACAPAP conferences in 2012 as a joint project of the European Federation of Psychiatric Trainees and the Early Career Psychiatrists Committee. The survey contained 14 questions related to general data, situation of transition in participant’s country and participant’s opinion on the concept of transition process. It was given to the randomly chosen participants (N=397).ResultsThe questionnaire was completed by 166 European participants from 28 European Countries. They were mostly men (N= 88, 53 %) and specialists (N=107, 64.5%). Nearly half (N=76, 45.8%) have contact with transition issues at least once per month. Data analysis is in progress, but preliminary results show that more than half of participants think the transition process could be significantly improved (N=94, 56,6%), and they are manly from Italy, Portugal, Germany, Ireland and Spain. Only one fourth is quite satisfied with the current situation (N= 45, 27,1%). The latter group in mainly from the UK.ConclusionsWe plan to use these results to broaden the study and gather more details regarding this issue in every European country
1513 – Exploratory Study Of Risk-taking And Self-harm Behaviours In Adolescents: Prevalence, Characteristics And Its Relationship To Attachment Styles
Authors: Paiva A.C. , Cunha M. , Xavier A.M. , Marques M. , Simões S. , Espírito Santo H. 
Published: July 2013

IntroductionRisk-taking (RT) and self-harm (SH) occur across the lifespan, but many types of RT and SH typically appear for the first time in adolescence. According to Vrouva, Fonagy, and Fearon (2010), it is important to measure RT and SH simultaneously because they are clinically, empirically, and conceptually linked.Objectives(1)analyse the prevalence of risk-taking and self-harm behaviours in community adolescents, controlling the effect of genderand age;(2)examine the link between RT and SH behaviours;(3)investigate the relationship between attachment style and RT and SH behaviours.Methods346 adolescents (girls: n = 194, 56%) aged between 12 and 18 years (M = 15.10, SD = 1.77) completed a sociodemographic questionnaire, the Risk-Taking and Self-Harm Inventory for Adolescents (RTSHIA) and the Attachment Questionnaire for Children (AQ-C).ResultsRT behaviours more prevalent are taking chances while doing one’s hobbies, smoking tobacco and cheating. SH behaviours more frequent are self-demeaning thoughts and behaviours intentionally. Boys showed higher RT behaviours than girls. There is a positive association between age and both behaviours (RT and SH). Insecurely attached teenagers reported higher SH behaviours than did securely attached adolescents.ConclusionsThis study shows the prevalence of RT and SH behaviours in a community sample of adolescents, showing how gender and age can influence the expression of both behaviors. It seems that secure attachment may be protective to the engagement in SH behaviors, strengthening the important role of quality of relationships on psychological adjustment in adolescents
1515 – Collaborative Care Approaches For People With Severe Mental Illness: The Results From a Cochrane Collaboration Review
Authors: Reilly S. , Planner C. , Gask L. , Hann M. , Knowles S. , Druss B. , Helen L. 
Published: July 2013

IntroductionCollaborative care is a community based intervention which typically consists of a number of components. The intervention aims to improve the physical and/or mental health and health care of people with a severe mental illness (SMI).ObjectivesTo explore how collaborative care is implemented.To assess the effectiveness of collaborative care approaches in comparison to standard care for people with SMI who are living in the community.MethodsA Cochrane Review: The Cochrane Schizophrenia Group Specialised register was searched in April 2011. Fifty one experts in the field of SMI and collaborative care were also contacted.ResultsWe included one RCT (306 participants; US veterans with bipolar disorder I or II) in this review. The trial provides data for one comparison: collaborative care versus standard care The reanalysis of data from the one included study indicated that collaborative care significantly reduced psychiatric admissions at year 2 in comparison to standard care (N= 306, 1 RCT, RR 0.75, 95% CI 0.57 to 0.99). Direct intervention (all-treatment) costs of collaborative care at the three year follow up did not differ significantly from standard care,mean difference -$2981.00 (N= 306, 1 RCT95% CI $16934.93 to $10972.93).ConclusionsOne trial at moderate risk of bias suggests that collaborative care may significantly reduce psychiatric admissions. More large, well designed, conducted and reported trials may be required to determine the effects of collaborative care and help inform healthcare professionals and policy makers about the value of collaborative care for people with SMI