bluuebunny/crossref_metadata_2025_split huggingface dataset:
Anti-Biofilm Effect of Nanometer Scale Silver (NmSAg) Coatings on Glass and Polystyrene Surfaces against P. Mirabilis, C. Glabrata and C. Tropicalis Strains
Authors: Sahal Gulcan , Nasseri Behzad , Bilkay Isil Seyis , Piskin Erhan 
Published: October 2015

Purpose Nowadays, in order to terminate biofilm associated infections, coating of particular biomaterial surfaces with particular substances, via some nanotechnological tools, is being applied. Therefore, in the present study, investigation of anti-biofilm effects of nanometer scale silver (NmSAg) coatings on glass and polystyrene surfaces against clinical strains of Proteus mirabilis, Candida glabrata and Candida tropicalis was aimed. Methods In this study, glass and polystyrene slabs with 1.5 cm × 1.5 cm × 0.3 mm dimensions were cleaned by using surface plasma technology, covered with NmSAg by using a physical vapor deposition machine, and biofilm inhibition was determined by crystal violet binding assay. Results According to our results, 32 nm of silver layer on a glass slab decreased biofilm formation of P. mirabilis strain to a maximum amount of 88.1% and caused 20.9% inhibition in biofilm formation of C. glabrata strain. On the other hand, NmS coating of Ag on a polystyrene slab caused 34.4% and 20% inhibitions, respectively, in biofilm formations of C. glabrata and C. tropicalis strains. Although biofilm inhibition of NmSAg layer on polystyrene slab was more (34.4%) than biofilm inhibition caused by NmSAg layer on glass slab (20.9%), C. glabrata strain's biofilm formation on uncoated glass slab was lower than both uncoated and NmSAg-coated polystyrene slabs. Conclusions Our results show that glass surfaces with NmSAg coatings can be used as a new surface material of various indwelling devices on which P. mirabilis colonizations frequently occur and in order to avoid C. glabrata-associated biofilm infections, it is more useful to choose a surface material of glass rather than choosing a surface material of polystyrene.
Transcatheter Anastomosis Connector System for Vascular access Graft Placement: Results from a First-in-human Pilot Study
Authors: Ebner Adrian , Ross John R. , Setum Cindy M. , Kallok Michael J. , Yevzlin Alexander S. 
Published: October 2015

Purpose A lengthy healing and maturation period follows standard surgical preparation of a permanent arteriovenous access, often requiring or extending use of a venous catheter (VC) for hemodialysis. The InterGraft™ Anastomotic Connector System was developed for minimally invasive anastomosis of an arteriovenous graft (AVG). The venous and arterial InterGraft™ connectors are designed to provide optimized flow dynamics and may result in reduction of AVG stenosis. This pilot study evaluated placement procedure success, patency and safety of the InterGraft™ connectors. Methods Nine AVGs were implanted in nine patients currently receiving dialysis with a VC. The study allowed use of both connectors (n = 5) or use of the venous connector with a sutured arterial anastomosis (n = 4). Monthly ultrasound examinations were performed throughout the six-month follow-up. AVG angiography was performed at five months. Endpoints included procedure success (acceptable graft flow at end of procedure, without significant bleeding or need for emergent surgery), patency, and device-related major adverse events. Results Procedure success was attained in all patients. AVGs were used for dialysis within 17 days, on average, and VCs were removed. Three patients exited the study early for reasons unrelated to the InterGraft™ connectors. The remaining six patients had patent grafts: two with assisted and four with unassisted patency. AVG flow rates were greater than 1 L/minute. No dilatations or aneurysms were observed by angiography. There were no device-related major adverse events. Conclusions The InterGraft™ connectors can be safely and successfully used for AVG anastomoses, with acceptable near-term patency. Further clinical evaluation is warranted.
Orbital Exenteration: Our Experience
Authors: Maria di Alessandra , Balia Laura , Mario Poletti Arturo , Colombo Giovanni , Romano Mary 
Published: October 2015

Introduction We reviewed our experience of the multidisciplinary collaboration between ophthalmologists, head and neck surgeons, neurosurgeons, radiologists and oncologists in the management of extensive tumors treated by orbital exenteration at the Humanitas Research Institute, Milan, Italy, over the past 10 years. Methods This is a retrospective cohort study of all patients who underwent orbital exenteration between March 2005 and August 2014 at the Humanitas Research Institute. The 10-year cohort of exenterated patients was identified through operating room notes using the clinical code set of the International Classification of Diseases, 10th revision (ICD-10). Results A total of 26 patients were identified, including 19 (73.1%) males. The median age was 65.5 years (range 37-87). Eighteen (69.2%) patients had major skin cancers extending to the orbit. Patients were divided into 2 cohorts: cohort 1 comprising patients with sinus or craniofacial cancers requiring orbital exenteration, and cohort 2 comprising patients with advanced periorbital skin cancers. The two cohorts were well matched for sex, age at surgery, degree of invasion, extension of surgical removal, necessity of adjuvant radiotherapy, reconstruction processes, and rehabilitation. Conclusions In our experience patients never died of the primary lesion but because of the occurrence of other problems. So we encourage local surgical radicality.
Concise Review: Stem Cell Microenvironment on a Chip: Current Technologies for Tissue Engineering and Stem Cell Biology
Authors: Park DoYeun , Lim Jaeho , Park Joong Yull , Lee Sang-Hoon 
Published: October 2015

Abstract

Stem cells have huge potential in many therapeutic areas. With conventional cell culture methods, however, it is difficult to achieve in vivo-like microenvironments in which a number of well-controlled stimuli are provided for growing highly sensitive stem cells. In contrast, microtechnology-based platforms offer advantages of high precision, controllability, scalability, and reproducibility, enabling imitation of the complex physiological context of in vivo. This capability may fill the gap between the present knowledge about stem cells and that required for clinical stem cell-based therapies. We reviewed the various types of microplatforms on which stem cell microenvironments are mimicked. We have assigned the various microplatforms to four categories based on their practical uses to assist stem cell biologists in using them for research. In particular, many examples are given of microplatforms used for the production of embryoid bodies and aggregates of stem cells in vitro. We also categorized microplatforms based on the types of factors controlling the behaviors of stem cells. Finally, we outline possible future directions for microplatform-based stem cell research, such as research leading to the production of well-defined environments for stem cells to be used in scaled-up systems or organs-on-a-chip, the regulation of induced pluripotent stem cells, and the study of the genetic states of stem cells on microplatforms.

Significance
Stem cells are highly sensitive to a variety of physicochemical cues, and their fate can be easily altered by a slight change of environment; therefore, systematic analysis and discrimination of the extracellular signals and intracellular pathways controlling the fate of cells and experimental realization of sensitive and controllable niche environments are critical. This review introduces diverse microplatforms to provide in vitro stem cell niches. Microplatforms could control microenvironments around cells and have recently attracted much attention in biology including stem cell research. These microplatforms and the future directions of stem cell microenvironment are described.
Quels défis pour l’histoire de la traduction et de la traductologie ?
Authors: D’hulst Lieven 
Published: October 2015

Dans un ouvrage récent (D’hulst 2014), j’ai plaidé pour une histoire de la traduction moins préoccupée par son positionnement au sein de la traductologie ou en bordure d’autres pratiques savantes prêtes à lui ménager une place (l’histoire culturelle et sociale, l’histoire des sciences, de la philosophie, de la littérature, de la linguistique, etc.) que par la spécificité et par la valeur du point de vue historiographique sur la traduction. Il s’agirait corrélativement de définir les objets et les méthodes au service de l’étude historique de ces derniers, en dialogue avec les savoirs et disciplines qui gravitent autour de celle-ci et lui procurent des concepts et des modélisations. Il s’agirait aussi de montrer la signification sinon l’importance des recherches historiques sur les traductions et les savoirs traductifs au regard d’autres activités intellectuelles et sociales. Ces différents défis forment l’objet de cette contribution ; elle s’appuiera sur des exemples puisés dans un éventail de domaines, périodes et aires culturelles.
Spatial distribution of magnetic fluctuation power with period 40 to 600 s in the magnetosphere observed by THEMIS
Authors: Wang G. Q. , Zhang T. L. , Ge Y. S. 
Published: October 2015

AbstractUltralow frequency (ULF) fluctuations are ubiquitous in the magnetosphere and have significant influence on the energetic particle transport. We use Time History of Events and Macroscale Interactions during Substorms (THEMIS) data to give the spatial distribution of the Pi2/Pc4 and Pc5 band magnetic fluctuation amplitude near the magnetic equator in the magnetosphere. Statistical results can be summarized as follows: (1) strong ULF fluctuations are common in the magnetotail plasma sheet; the amplitude of all three components of magnetic fluctuations decreases with decreasing radial distance; (2) during periods of high AE index, fluctuations can propagate toward the Earth as far as the data cutoff in the nightside of the magnetosphere, and the amplitude of magnetic fluctuations is clearly stronger near the dusk sector of the synchronous orbit than that near the dawn sector, suggesting that the substorm particle injection has significant contribution to these fluctuations; (3) intense compressional Pc5 band magnetic fluctuations are a persistent feature near two flanks of the magnetosphere. Clear peaks of the compressional Pi2/Pc4 band magnetic fluctuation power near two flanks can be found during periods of fast solar wind, while the power of compressional Pi2/Pc4 band fluctuations is weak when the solar wind is slow. (4) Solar wind dynamic pressure and its variations can globally affect the ULF fluctuation power in the magnetosphere. Magnetic fluctuations near the noonside can penetrate from the magnetopause to the synchronous orbit or inner when solar wind pressure variations are large.
Assessing the Role of Capping Molecules in Controlling Aggregative Growth of Gold Nanoparticles in Heated Solution
Authors: Cheng Han‐Wen , Schadt Mark J. , Zhong Chuan‐Jian 
Published: October 2015

AbstractThis report describes findings of an investigation of the role of capping molecules in the size growth in the aggregative growth of pre‐formed small‐sized gold nanoparticles capped with alkanethiolate monolayers toward monodispersed larger sizes. The size controllability depends on the thiolate chain length and concentration in the thermal solution. The size evolution in solution at different concentrations of alkanethiols is analyzed in relation to adsorption isotherms and cohesive energy. The size dependence on thiolate chain length is also analyzed by considering the cohesive energy of the capping molecules, revealing the importance of cohesive energy in the capping structure. Theoretical and experimental comparisons of the surface plasmonic resonance optical properties have also provided new insights into the mechanism, thus enabling the exploitation of size‐dependent nanoscale properties.
Guaranteed Cost Control of Networked Control Systems Under Transmission Control Protocol with Active Queue Management
Authors: Zhu Qixin , Lu Kaihong , Zhu Yonghong 
Published: October 2015

AbstractThe problem of a guaranteed cost controller design of networked control systems under transmission control protocol (TCP) is derived. To improve the overall performance of the networked control system, a scheme to simultaneously control the plant and the network is presented. An analytical TCP model is used to design active queue management (AQM) to achieve the desired queue length, which is helpful in reducing the variation of the network induced delay. Moreover, a new closed loop model of networked control systems is obtained by augmenting the TCP communication model with the control plant. The guaranteed cost controller is addressed in terms of a linear matrix inequality (LMI) to render the system asymptotically stable based on Lyapunov‐Krasovskii theory and weighted technology. Finally, numerical simulations are included to demonstrate the theoretical results.
Fabrication of multiwalled carbon nanotube–polyaniline/platinum nanocomposite films toward improved performance for a cholesterol amperometric biosensor
Authors: Xu ZeHong , Cheng XiaoDan , Tan JianHong , Gan Xianxue 
Published: October 2015

AbstractA simple and high sensitive cholesterol amperometric biosensor, which is based on in situ electropolymerization of multi‐walled carbon nanotube‐polyaniline (MWCNT‐PANI) nanocomposite and electrodeposition of platinum nanoparticle (nano‐Pt) films onto the glassy carbon electrode surface for cholesterol oxidase immobilization, was constructed in this study. The preparation process of the modified electrode was characterized by cyclic voltammetry, electrochemical impedance spectroscopy, scanning electron microscopy, and chronoamperometry. Because of the synergistic electrocatalytic activity between MWCNT‐PANI nanocomposites and nano‐Pt, the cholesterol biosensor exhibited an excellent performance with a linear range of 2.0–510.0 µM, a detection limit of 0.8 µM (signal‐to‐noise ratio = 3), a high sensitivity of 109.9 µA mM−1, and a short response time within 5 Sec. Moreover, the reproducibility, stability, and selectivity of the biosensor were also investigated.
RNA approaches the B‐form in stacked single strand dinucleotide contexts
Authors: Sedova Ada , Banavali Nilesh K. 
Published: October 2015

ABSTRACTDuplex RNA adopts an A‐form structure, while duplex DNA interconverts between the A‐ and B‐forms depending on the environment. The C2′‐endo sugar pucker seen in B‐form DNA can occur infrequently in ribose sugars as well, but RNA is not understood to assume B‐form conformations. Through analysis of over 45,000 stacked single strand dinucleotide (SSD) crystal structure conformations, this study demonstrates that RNA is capable of adopting a wide conformational range between the canonical A‐ and B‐forms at the localized SSD level, including many B‐form‐like conformations. It does so through C2′‐endo ribose conformations in one or both nucleotides, and B‐form‐like neighboring base stacking patterns. As chemical reactions on nucleic acids involve localized changes in chemical bonds, the understanding of how enzymes distinguish between DNA and RNA nucleotides is altered by the energetic accessibility of these rare B‐form‐like RNA SSD conformations. The existence of these conformations also has direct implications in parametrization of molecular mechanics energy functions used extensively to model nucleic acid behavior., 2016. © 2015 Wiley Periodicals, Inc. Biopolymers 105: 65–82, 2016
Syntheses, Structure, and Properties of Four Metal‐Organic Polymers Based on Rigid Multiple Carboxylate Ligands and N‐Donor Ligands
Authors: Zhou Yong , Zhao Wen‐Hao , Wang Jin , Wei Jin‐Rui , Yin Xian‐Hong , Wei Xiang‐Bo , Lin Cui‐Wu 
Published: October 2015

Four metal‐organic coordination polymers, {[Cd2(BIBP)2(H2DTDA)2]
n
· 2(H2O)} (1), [Zn (BIBP) (H2TDA)2]
n
(2), [Cd2(BIBP)(H2TDA)2]
n
(3), and [Ni2(BIBP)2(H2DTDA)2(μ‐O)]
n

, (4) [where BIBP = 4,4′‐bis(1‐imidazoly)biphenyl, H2TDA = [1,1′:4′1″‐terphen‐yl]‐3,3″‐dicarboxylic acid, and H2DTDA = 2′,5′‐dimethyl‐[1,1′:4′,1″‐terphenyl]‐3,3″‐dicarboxylic acid] were hydrothermally synthesized and characterized by elemental analyses, IR, TG, luminescence, and single crystal X‐ray diffraction. X‐Ray diffraction analysis reveals that the four complexes exhibit new frameworks due to diverse coordination conformations. The different coordination modes of the ligands BIBP and two aromatic carboxylate acids play important roles in the construction of the final structure for the complexes. X‐ray structure analysis reveals that 1, 2, and 4 are 3D coordination polymers, while complex 3 is a 2D network polymer.
Guided inquiry activities for learning about the macro‐ and micronutrients in introductory nutrition courses
Authors: Smith Andri L. , Purcell Rebecca J. , Vaughan Joel M. 
Published: October 2015

AbstractMost students enroll in general education introductory nutrition classes because they want to improve their diets in order to lose weight or enhance athletic performance. These nonscience majors are often less interested in learning about the fundamental biochemical principles underlying nutrition or are surprised that this foundational knowledge of biochemistry is essential for appropriate diet planning. Furthermore, nonscience majors sometimes find traditional, lecture‐oriented science classes that encourage competition rather than collaboration to be uninviting and unappealing. For these reasons, we have developed a set of guided inquiry activities about macronutrients (carbohydrates, lipids, and proteins) and micronutrients (vitamins and minerals) for use in introductory nutrition courses for nonscience majors. In our first study (Spring 2012), we divided students into two groups with two different approaches for learning about the macronutrients: (1) a traditional, lecture‐based approach and (2) an active learning approach with guided inquiry activities. We showed through the use of embedded common exam questions that students mastered concepts related to the macronutrients equally well using either approach. Due to positive student and faculty feedback from the first study, we decided to have all students use the guided inquiry approach in a subsequent study the following year (Spring 2013). In our second study we used pre/post survey data to evaluate both students' concept mastery and confidence in answering questions about the macro‐ and micronutrients. We found that (1) students showed gains in both concept mastery and confidence and (2) as students' confidence increased, post‐test concept scores also increased. © 2015 by The International Union of Biochemistry and Molecular Biology, 43:449–459, 2015.
Severe scalp hair loss in a female patient with acromegaly treated with lanreotide autogel after unsuccessful surgery
Authors: Alvarez‐Escola Cristina , Cárdenas‐Salas Jersy J. , Pelegrina Beatriz , Sanz‐Valtierra Angel , Lecumberri Beatriz 
Published: October 2015

Key Clinical MessageScalp hair loss is an underreported adverse event of somatostatin analogs therapy that in severe cases may require treatment withdrawal. It can be related to an acute decrease in GH/IGF‐1 levels, but a direct effect cannot be ruled out.
Improving the Electrochemical Performance of Li1.14Ni0.18Mn0.62O2 by Modulating Structure Defects via a Molten Salt Method
Authors: Zhang Tao , Li Jun‐Tao , Liu Jie , Deng Ya‐Ping , Wu Zhen‐Guo , Yin Zu‐Wei , Wu Jiao‐Hong , Huang Ling , Sun Shi‐Gang 
Published: October 2015

AbstractNanocrystalline Li1.14Ni0.18Mn0.62O2 cathode materials are synthesized by a molten salt method using KCl as the molten agent. The influence of the sintering temperature and the mass ratio of KCl to Li1.14Ni0.18Mn0.62O2 on the structure and electrochemical performance are investigated. The sintering temperature can markedly affect the formation of the layered structure and the content of stacking faults. The amount of KCl influences the cation ordering of the materials. The ratios of Li+/Ni2+ replacement for the materials obtained at 800 °C with a KCl amount of R=4, 8, and 12 [R=m(KCl)/m(Li1.14Ni0.18Mn0.62O2)] are 16.51, 8.39, and 4.46 %, respectively. A lower steric hindrance—related to a better cationic ordering—is obtained when the amount of KCl is increased, which is in agreement with the tendency of the Li+ diffusion coefficient. This study demonstrates a new approach to control the Li+/Ni2+ replacement in lithium‐rich layered cathode materials to improve their electrochemical performance.
A Palladium‐ and Copper‐Catalyzed Synthesis of Dihydro[1,2‐b]indenoindole‐9‐ol and Benzofuro[3,2‐b]indolines: Metal‐Controlled Intramolecular CC and CO Bond‐Forming Reactions
Authors: Boominathan Siva Senthil Kumar , Wang Jeh‐Jeng 
Published: October 2015

AbstractA palladium‐ and copper‐catalyzed synthesis of dihydro[1,2‐b]indenoindole‐9‐ol and benzofuro[3,2‐b]indolines has been developed, whereby the same starting material is employed for the synthesis of both heterocyclic scaffolds and the selectivity of the product is controlled by switching the choice of metal. Salient features of these cascade reactions include wide‐ranging functional group tolerance, simple reaction conditions, and moderate to high yields.
Mass Flow Analysis and Metal Losses by the Degradation Process of Organic‐Containing WEEE Scraps
Authors: Diaz Fabian , Florez Sebastian , Friedrich Bernd 
Published: October 2015

AbstractIn the past years the topic of WEEE recycling has gained more relevance due to increased production and reduced effectiveness in metal recovery. Therefore, new processing technologies are evolving today as result of the increasing heterogeneity of WEEE. Such is the case of pyrolysis as an upgrading and conditioning method for different types of complex scraps, which also facilitate further mechanical separation of metal as well as production of an alternative fuel source. In this work, it has been concluded that pyrolysis can be easily integrated as a preprocessing step in a resource efficient recycling route.
Correlation of the New York Heart Association Classification and the 6‐Minute Walk Distance: A Systematic Review
Authors: Yap Jonathan , Lim Fang Yi , Gao Fei , Teo Ling Li , Lam Carolyn Su Ping , Yeo Khung Keong 
Published: October 2015

ABSTRACTBackgroundFunctional status assessment is the cornerstone of heart failure
management and trials. The New York Heart Association (NYHA) classification and 6‐minute walk distance (6MWD) are commonly used tools; however, the correlation between them is not well understood.HypothesisWe hypothesised that the relationship between the NYHA classification and 6MWD might vary across studies.MethodsA systematic literature search was performed to identify all studies reporting both NYHA class and 6MWD. Two reviewers independently assessed study eligibility and extracted data. Thirty‐seven studies involving 5678 patients were included.ResultsThere was significant heterogeneity across studies in 6MWD within all NYHA classes: I (n = 16, Q = 934.2; P < 0.001), II (n = 25, Q = 1658.3; P < 0.001), III (n = 30, Q = 1020.1; P < 0.001), and IV (n = 6, Q = 335.5; P < 0.001). There was no significant difference in average 6MWD between NYHA I and II (420 m vs 393 m; P = 0.416). There was a significant difference in average 6MWD between NYHA II and III (393 m vs 321 m; P = 0.014) and III and IV (321 m vs 224 m; P = 0.027). This remained significant after adjusting for region of study, age, and sex.ConclusionsAlthough there is an inverse correlation between NYHA II–IV and 6MWD, there is significant heterogeneity across studies in 6MWD within each NYHA class and overlap in 6MWD between NYHA I and II. The NYHA classification performs well in more symptomatic patients (NYHA III/IV) but less so in asymptomatic/mildly symptomatic patients (NYHA I/II). Nonetheless, the NYHA classification is an easily applied first‐line tool in everyday clinical practice, but its potential subjectivity should be considered when performing comparisons across studies.