bluuebunny/crossref_metadata_2025_split huggingface dataset:
Questions of quality in repositories of open educational resources: a literature review
Authors: Atenas Javiera , Havemann Leo 
Published: July 2014

Open educational resources (OER) are teaching and learning materials which are freely available and openly licensed. Repositories of OER (ROER) are platforms that host and facilitate access to these resources. ROER should not just be designed to store this content – in keeping with the aims of the OER movement, they should support educators in embracing open educational practices (OEP) such as searching for and retrieving content that they will reuse, adapt or modify as needed, without economic barriers or copyright restrictions. This paper reviews key literature on OER and ROER, in order to understand the roles ROER are said or supposed to fulfil in relation to furthering the aims of the OER movement. Four themes which should shape repository design are identified, and the following 10 quality indicators (QI) for ROER effectiveness are discussed: featured resources; user evaluation tools; peer review; authorship of the resources; keywords of the resources; use of standardised metadata; multilingualism of the repositories; inclusion of social media tools; specification of the creative commons license; availability of the source code or original files. These QI form the basis of a method for the evaluation of ROER initiatives which, in concert with considerations of achievability and long-term sustainability, should assist in enhancement and development.Keywords: open educational resources; open access; open educational practice; repositories; quality assurance(Published: 24 July 2014)Citation: Research in Learning Technology 2014, 22: 20889 -http://dx.doi.org/10.3402/rlt.v22.20889
Real-time handheld emission spot allocator (rthESA) for simultaneous fusion imaging with ultrasound
Authors: Winkens T. , Kühnel C. , Freesmeyer M. 
Published: July 2014

SummaryObjectives: First, to report on initial experiences and technical parameters of a newly developed real-time handheld emission spot allocator (rthESA), and second, to report on the simultaneous acquisition of rthESA and US data as rthESA/US fusion images. Methods: The rthESA consisted of five semiconductor-detectors arranged in alternate position in two rows. This design allowed the examination of focal activities in the same plane as US. The signals were interpreted by an ad hoc software and the real-time allocation of spot radiation sources within air- and water phantoms was investigated for 99mTc, 131I, and 18F. A compact US probe was fixed in plane with the rthESA and connected to a standard US equipment. Experiments with a liver phantom were performed to verify the integration of 99mTc-rthESA data and US images. Results: The allocation proved to be successful for all radionuclides. The system showed a noticeable performance latency, most pronounced for positions far from the detector (1 cm distance: 0.7 ± 0.5 s; 4 cm distance: 6.1 ± 3.2 s). Within the liver phantom, the rthESA enabled the correct allocation of a spot radiation source within a live US image. Conclusions: The rthESA allowed an exact localization of spot radiation sources in single plane, with additional consideration of the distance from the detector, leading to real-time allocation and simultaneous overlay with US images. In spite of clear technical limitations in need of further development, this proof-of-concept study shows that this hybrid detector has the potential to provide integrated simultaneous nuclear medicine and US images.
CD326loCD103loCD11blo Dermal Dendritic Cells Are Activated by Thymic Stromal Lymphopoietin during Contact Sensitization in Mice
Authors: Ochiai Sotaro , Roediger Ben , Abtin Arby , Shklovskaya Elena , Fazekas de St. Groth Barbara , Yamane Hidehiro , Weninger Wolfgang , Le Gros Graham , Ronchese Franca 
Published: July 2014

Abstract
The cytokine thymic stromal lymphopoietin (TSLP) is produced by epithelia exposed to the contact sensitizer dibutyl phthalate (DBP), and it is critical for the induction of Th2 immune responses by DBP-FITC. TSLP is thought to act on dendritic cells (DC), but the precise DC subsets involved in the response to TSLP remain to be fully characterized. In this study we show that a subset of CD326loCD103loCD11blo dermal DC, which we termed “triple-negative (TN) DC,” is highly responsive to TSLP. In DBP-FITC–treated mice, TN DC upregulated expression of CD86 and rapidly migrated to the draining lymph node to become the most abundant skin-derived DC subset at 24 and 48 h after sensitization. None of these responses was observed in TSLPR-deficient mice. In contrast, TN DC numbers were not increased after treatment with the allergen house dust mite or the bacteria Escherichia coli and bacillus Calmette–Guérin, which increased other DC subsets. In vivo, treatment with rTSLP preferentially increased the numbers of TN DC in lymph nodes. In vitro, TN DC responded to rTSLP treatment with a higher level of STAT5 phosphorylation compared with other skin-derived DC subsets. The TN DC subset shared the morphology, phenotype, and developmental requirements of conventional DC, depending on FLT3 expression for their optimal development from bone marrow precursors, and CCR7 for migration to the draining lymph node. Thus, TN DC represent a dermal DC subset that should be considered in future studies of TSLP-dependent contact sensitization and skin immune responses.
A Comparison of Rangeland Monitoring Techniques for Modeling Herbaceous Fuels and Forage in Central Arizona, USA
Authors: Rhodes Edward C. , Tolleson Doug R. , Angerer Jay P. , Kava John A. , Dyess Judith , Nicolet Tessa 
Published: July 2014

AbstractWhile fire and rangeland managers frequently have different land management roles and objectives, their data needs with regards to herbaceous biomass (fuel loads and forage) often overlap, and can be served with a single sampling protocol for both rangeland and fuels management. In this study, we examined how two herbaceous sampling methods compare in measuring species richness, ground cover, and standing herbaceous biomass for range and forestry management using the Phytomass Growth Simulator (Phygrow). Phygrow is an herbaceous vegetation growth model used to simulate rangeland plant production for herbivory, drought, and wildfire severity early warning systems. The Point-frequency protocol has been used for 10 years to collect plant community parameters for Phygrow. The Common Non-Forested Vegetation Sampling Protocol (CNVSP) is a commonly used rangeland assessment protocol in the southwestern United States. Data from both methods were used to parameterize the Phygrow model to examine their similarities and differences, and to see if data collected from the CNVSP methodology could be used to model herbaceous fuel loads. We determined that the data collected in the CNVSP protocol met the needs for Phygrow model validation of standing herbaceous fuels, but data was insufficient for modeling surface dead fuel loads.
Case report of complicated epidermoid cyst of the floor of the mouth: Radiology-histopathology correlation
Authors: Mirza Salman , Fadl Shaima , Napaki Sarbar , Abualruz AbdulRahman 
Published: July 2014

Epidermoid cysts, true dermoid cysts and teratoid cysts compose the spectrum of cystic teratomas, which are defined as neoplasms whose tissue are derivatives of more than one germ layer, foreign to that part of the body from which the tumor arises. Epidermoid cysts of the floor of the mouth are rare lesions and are much less common than dermoid cysts in the head and neck. This case reports a 43-year-old male patient who presented with a longstanding midline swelling in the submental region. Initial imaging was done using ultrasound followed by computed tomography (CT) scan. Biopsy was taken and revealed a cyst wall lined with epidermal squamous epithelium along with areas of focal ulceration suggesting chronic inflammatory changes of the wall of the epidermoid cyst.There are characteristic and even pathognomonic imaging features of epidermoid cysts at the floor of the mouth in ultrasound and CT scan. Imaging has an important role in the surgical management plan according to the size and location of the cyst in relation to geniohyoid and mylohyoid muscles.
Tuber melanosporum spread within sub-optimal climatic zones is controlled by fruiting triggers and not mycorrhiza survival
Authors: Thomas Paul W. 
Published: July 2014

<p><em>Tuber melanosporum</em> is the most valuable of all cultivatable truffle species. Farming of this species spans every continent with the exception of Antarctica. <em>Tuber aestivum</em> (syn. <em>T. uncinatum</em>) and <em>Tuber brumale</em> are truffle species that have similar host plant preference and a similar affinity for calcareous soils as <em>T. melanosporum</em>, but occur over a broader geographic zone. The geographic limit of <em>T. melanosporum</em> is thought to be climatically dictated but it is not known whether this is due to an impact on mycorrhizal survival or climatically-derived fruiting triggers. Here, data is compiled from five cultivated research sites in the climatically sub-optimal conditions of the UK in order to address this question. Here we show:</p><p><em>(</em><strong><em>i</em></strong><em>)Tuber melanosporum</em> mycorrhiza can survive and grow in sub-optimal climatic conditions.</p><p>(<strong><em>ii</em></strong>)It is climatically-derived fruiting triggers and not ectomycorrhiza survival that dictate the climatic preferences and geographic spread of <em>T. melanosporum</em>.</p><p>(<strong><em>iii</em></strong>)Important climatic parameters for potential fruiting triggers are sunshine hours, summer rainfall and summer temperatures.</p><p> </p><p>The data presented here not only aid our understanding of the ecological parameters of <em>T. melanosporum</em> but also have a practical application for truffle cultivators in choosing suitable locations for a plantation.</p>
Right Colon Carcinoma Infiltrating the Alimentary Limb in a Patient With Biliopancreatic Diversion
Authors: López-Tomassetti Fernández Eudaldo M. , Hernández Hernández Juan Ramón , Jorge Valentine Nuñez 
Published: July 2014

AbstractBiliopancreatic diversion (BPD) has excellent results, with the average patient losing 60% to 80% of the excess weight in the first 2 years. However, the BPD works by malabsorption and malabsorptive problems may be experienced with the operation. Therefore, monitoring is necessary for life. In the recent literature there is some debate over the possibility that this technique can increase the risk of colon cancer secondary to the action of the unabsorbed food and bile acid on colonic mucosa. We report the case of a 42-year-old patient with a previous bariatric surgery (BPD with 50 cm common channel; 300 cm alimentary limb) who developed a very aggressive right colon cancer 6 years after the operation. We also review our series of 330 patients operated on during a 14-year period to try to answer if there is any relationship between BPD and colon cancer.
Mesh Migration Into Urinary Bladder After Open Ventral Herniorrhaphy With Mesh: A Case Report
Authors: Su Yann-Rong , Chan Pei-Hui 
Published: July 2014

AbstractVentral hernia repair with mesh products is of increasing popularity. The long-term results of mesh repair of ventral hernia are superior to primary suture repair. However, occasional complications may still present. We report on a 77-year-old man who underwent ventral hernia repair with a mesh 5 years ago with complication of mesh migration into the urinary bladder and enterovesical fistula. The patient presented with lower urinary tract symptoms initially. By urinalysis, persistent hematuria and pyuria were found after antibiotic treatment. For further investigation of hematuria, intravenous urography was performed, which revealed a faint radio-opaque patch at the right pelvis. To obtain a more precise relationship between the lesion and the adjacent organs, computed tomography and cystoscopy were arranged. They confirmed a mesh with stone formation in the urinary bladder. To remove the mesh, segmental resection of the ileum and cystorrhaphy were performed.
Drainage of Periappendiceal Abscess and Removal of Free Fecalith—Extraperitoneal Approach
Authors: Chang Chian-Ro , Cheng Che-Yu 
Published: July 2014

Abstract
Treatment of complicated acute appendicitis is controversial. The dilemma is further complicated by presence of free fecalith in a well-circumscribed abscess, which has been repeatedly demonstrated to be a major predicting factor of treatment failure of nonoperative treatment of acute appendicitis complicated with appendiceal abscess. If left behind after drainage of the abscess, further operations for removal of retained fecalith or recurrence of abscess might be required. However, little had been stressed over the significance of removal of the free fecalith when it was first encountered. We report our experience of drainage of appendiceal abscess and removal of free fecalith by taking an extraperitoneal approach. Both of our cases made a smooth recovery without any complication or recurrence after a 2-year follow-up. Treatment with this approach avoids many of the complications associated with formal laparotomy. Unlike image-guided drainage or laparoscopic drainage, this procedure is relatively simple and straightforward and can be performed in any level of hospital, including private practitioners and in less well-developed areas and countries. With proper case selection, we recommend this approach as one of the alternatives in the treatment of late-presenting appendiceal abscess with free fecalith.
Microsurgical Intermediate Subinguinal Varicocelectomy
Authors: Lee Joo Yong , Yu Ho Song , Ham Won Sik , Kang Dong Hyuk , Kim Kyu Hyun , Chung Doo Yong , Cho Kang Su 
Published: July 2014

AbstractThis study was conducted to introduce a simple modification that can facilitate microsurgical subinguinal varicocelectomy (MSV) especially for surgeons inexperienced in microsurgical technique. A single surgeon performed microsurgical intermediate subinguinal varicocelectomy (MISV) on 52 patients with 61 cases between September 2010 and August 2012. Patient age, varicocele grade, operation time, intraoperative findings, postoperative complications, and 3-month follow-up results were analyzed. Patient mean age was 28 years (range, 15–69 years), and there were 9 bilateral cases. The mean operative time was 51 minutes (range, 34–109 minutes). We compared the first 31 cases to the second 30 cases, to assess investigator experience on operating times. The mean number of ligated veins was 5 (range, 3–10) in internal spermatic vein, 1 (range, 0–4) in external spermatic vein, and 1 (range, 0–3) in gubernacular vein. In 28 patients, the average postoperative sperm concentration at the 3-month follow-up was significantly higher than the preoperative sperm concentration (28.5 ± 18.2 × 106/mL versus 10.5 ± 23.0 × 106/mL; P = 0.003). Mean motility improved after MSIV (65.7% ± 18.2% versus 47.2% ± 21.7%; P = 0.004). In conclusion, MISV appears comparable with MSV in terms of the high success rate, low complication rate, and low postoperative pain; and it can be easily accomplished by inexperienced surgeons.
Delayed Arterial Hemorrhage After Pancreaticoduodenectomy
Authors: Suzumura Kazuhiro , Kuroda Nobukazu , Kosaka Hisashi , Iimuro Yuji , Hirano Tadamichi , Fujimoto Jiro 
Published: July 2014

Abstract
Delayed arterial hemorrhage is a rare complication of pancreaticoduodenectomy that is associated with a high mortality and has no standard management. Between 2000 and 2011, 204 pancreaticoduodenectomies were performed, and there were 3 cases of delayed arterial hemorrhage. We reviewed the role of endoscopy, laparotomy, and interventional radiology the management of delayed hemorrhage. One patient presented with intraluminal bleeding and upper gastrointestinal endoscopy failed to identify the bleeding site. Two patients presented with bleeding from the drain tube. Laparotomy was performed in the patient with intraluminal bleeding and interventional radiology was employed for the other 2 patients. There was no hemorrhage-related mortality or rebleeding, but the patient who underwent laparotomy developed sepsis. Endoscopy may have no role in the initial management of delayed arterial hemorrhage after pancreaticoduodenectomy. Interventional radiology is less invasive compared with laparotomy, and may be considered as the first-line treatment for delayed arterial hemorrhage in pancreaticoduodenectomy patients.
Decreased Leakage Rate of Colonic Anastomoses by Tachosil Coating: An Experimental Study
Authors: Pommergaard Hans-Christian , Achiam Michael Patrick , Burcharth Jakob , Rosenberg Jacob 
Published: July 2014

Abstract
Colorectal anastomotic coating has been proposed as a means to lower the leakage rate. Prior to clinical testing, coating materials need thorough experimental evaluation to ensure safety and efficacy. The aim of this study was to evaluate Tachosil as an anastomotic coating agent. Technically insufficient colon anastomoses were created in 80 C57BL/6 mice, and in half of the animals the anastomoses were covered with Tachosil. The animals were examined for clinical signs of anastomotic leakage, and the breaking strength of the anastomoses was evaluated. The number of leakages was reduced by Tachosil coating (10/40 versus 20/40 in controls; P = 0.037). However, more cases of large bowel obstruction were found in the Tachosil group (12/40 versus 0/40 in controls; P &lt; 0.0005). Breaking strength was comparable between the Tachosil and control groups (0.49 N versus 0.52 N, respectively; P = 0.423). Clinical studies are needed to clarify the efficacy of Tachosil anastomotic coating.
The Effectiveness of a Rapid-Access Flexible Sigmoidoscopy Clinic in a District Hospital
Authors: Sorelli Paolo G. , Iliadis Alex D. , Payne John G. 
Published: July 2014

Abstract
Historically rapid-access colorectal clinics have had high proportions of nonconforming referrals from primary care physicians, which calls into question the clinics' efficacy. We aim to determine the effectiveness of our rapid-access flexible sigmoidoscopy clinic, and the adherence to the referral guidelines for suspected bowel cancer by general practitioners. We performed a 3-month retrospective audit to evaluate (1) the proportion of patients seen within 2 weeks, (2) the appropriateness of referrals, (3) the proportion of patients with findings, and (4) the proportion of patients who had further tests. A total of 59 patients (19 male, 40 female; age 35–86 years) were included in the study. All were offered an appointment within 2 weeks. Forty-one cases (82%) were appropriate referrals. Twenty-eight patients (47%) had pathology at sigmoidoscopy. Cancer pick-up rate was 6%. Thirty-seven patients (74%) had further investigations. We determined that our rapid-access clinic for symptomatic patients has high diagnostic accuracy and that access to early investigation is being used appropriately by general practitioners. In the current climate of spending cuts and streamlining services, our study confirms we are meeting targets for delivery of our colorectal service. The majority of referrals under the 2-week rule are appropriate. Rapid access to early investigation is being used appropriately by general practitioners contrasting previous studies with high proportions of nonconforming referrals.
Parastomal Hernia Containing Stomach
Authors: Barber-Millet Sebastian , Pous Salvador , Navarro Vicente , Iserte Jose , García-Granero Eduardo 
Published: July 2014

Abstract
Parastomal hernia is the most common late stomal complication. Its appearance is usually asymptomatic. We report a parastomal hernia containing stomach. A 69-year-old patient with end colostomy arrived at the emergency room presenting with abdominal pain associated with vomiting and functioning stoma. She had a distended and painful abdomen without signs of peritoneal irritation and pericolostomic eventration in the left iliac fossa. X-ray visualized gastric fornix dilatation without dilated intestine bowels, and computed tomography showed parastomal incarcerated gastric herniation. Gastrografin (Bayer Australia Limited, New South Wales, Australia) was administered, showing no passage to duodenum. She underwent surgery, with stomal transposition and placement of onlay polypropylene mesh around the new stoma. Parastomal hernias are a frequent late complication of colostomy. Only four gastric parastomal hernia cases are reported in the literature. Three of these four cases required surgery. The placement of prosthetic mesh in the moment of stoma elaboration should be considered as a potential preventive measure.
Carcinoma Cecum Presenting as Right Gluteal Abscess Through Inferior Lumbar Triangle Pathway—Report of a Rare Case
Authors: Karthikeyan Vilvapathy Senguttuvan , Sistla Sarath Chandra , Ram Duvuru , Ali Sheik Manwar , Velayutham Sugi Subramaniam Raghavan , Vijayaraghavan Nandhagopal 
Published: July 2014

AbstractGluteal abscess commonly follows intramuscular injections with contaminated needles. Carcinoma cecum is known to present with pericolic abscess due to microperforations and may rupture intraperitoneally. Gluteal abscess secondary to perforated carcinoma cecum with pericolic abscess is extremely uncommon. A 50-year-old woman who was receiving intramuscular iron injections for anemia presented with a 10 × 10-cm abscess in the right gluteal region and a vague mass in the right iliac fossa. After investigations, a diagnosis of perforated carcinoma cecum with pericolic abscess tracking into the right gluteal region was made, and incision and drainage were done. Fine-needle aspiration cytology from the cecal growth revealed adenocarcinoma. Unfortunately, the patient was not willing to undergo definitive treatment. This case is being reported for its rarity and as an uncommon etiology for a common condition.
Single-Incision Laparoscopic Surgery for a Small-Intestinal Gastrointestinal Stromal Tumor: Report of a Case
Authors: Sakai Makoto , Wada Wataru , Kimura Shintaro , Okada Akiko , Hirakata Tomoko , Onozato Ryoichi , Saito Kana , Morohara Koji , Osawa Hidenobu , Katayama Kazuhisa , Yasuda Naokuni , Tanaka Shigebumi , Kuwano Hiroyuki 
Published: July 2014

AbstractOur report concerns a 64-year-old man with a small-intestinal gastrointestinal stromal tumor (GIST), which was successfully treated with single-incision laparoscopic surgery (SILS). Small-bowel endoscopy detected a submucosal tumor located approximately 10 cm from the ligament of Treitz in the wall of the proximal jejunum. Contrast-enhanced computed tomography revealed a tumor (diameter, 4 cm) containing high- and low-density areas in the proximal jejunum. On 18F-fluorodeoxyglucose (FDG) positron-emission tomography (PET), the tumor demonstrated intense FDG uptake (maximum standard uptake value, 3.82), whereas it displayed high signal intensity on diffusion-weighted magnetic resonance images. No metastatic lesions were observed. The patient was diagnosed with a jejunal GIST. Wedge resection of the jejunum was performed using the SILS procedure. The tumor was histopathologically diagnosed as a low-grade malignant GIST. SILS is a useful resection technique for small-intestinal GIST.