bluuebunny/crossref_metadata_2025_split huggingface dataset:
On Verhoeff’s Otostigmus subgenus Malaccopleurus, the nudus group of <br />Otostigmus subgenus Otostigmus Porat, 1876, and Digitipes Attems, 1930, with a description of the foetus stadium larva in O. sulcipes Verhoeff, 1937, (Chilopoda: Scolopendromorpha: Scolopendridae)
Authors: LEWIS JOHN G. E. 
Published: November 2015

The species of Verhoeff’s Southeast Asian subgenus Malaccopleurus (an unavailable name) are here assigned to subgenus Otostigmus. His Otostigmus (M.) trisulcatus Verhoeff, 1937 is a junior subjective synonym of O. (M.) sulcipes Verhoeff, 1937. The foetus stadium of O. sulcipes is described. Otostigmus (M.) sutteri Würmli, 1972, is also assigned to the subgenus Otostigmus and may be conspecific with O. geophilinus Haase, 1887, the specimens of which show some variation. The specimen from Teinzo, Myanmar with labels O. politus Karsch, 1881, and O. geophilinus is of uncertain identity. Otostigmus sulcipes closely resembles O. nudus Pocock, 1890, and O. taeniatus Pocock, 1896, of Lewis’s (2010) nudus group. Otostigmus lawrencei Dobroruka, 1968, resembles a Cormocephalus species and is of uncertain identity. The genus Digitipes is characterised by the process on the femur of the ultimate legs in males. Three African species have been recognised. The males of Digitipes verdascens Attems, 1930, D. reichardti (Kraepelin, 1903) are known but D. krausi Dobroruka, 1968, lacks the femoral process and was described as a female. In these three species, only the tergite of the ultimate leg-bearing segment is marginate but in other characters D. krausi resembles Otostigmus species and is assigned to Otostigmus as O. krausi (Dobroruka, 1968) comb. nov. The Indian Digitipes periyarensis Joshi & Edgecombe, 2013, which differs markedly from other Digitipes species is a junior subjective synonym of Otostigmus nudus. It is possible that future molecular studies may show that some species currently assigned to Otostigmus are, in fact, Digitipes.
Impacts of Gulf of Mexico SST Anomalies on Southern Plains Freezing Precipitation: ARW Sensitivity Study of the 28–30 January 2010 Winter Storm
Authors: Mullens Esther D. , Leslie Lance M. , Lamb Peter J. 
Published: November 2015

AbstractIce storms are an infrequent but significant hazard in the U.S southern Great Plains. Common synoptic profiles for freezing precipitation reveal advection of low-level warm moist air from the Gulf of Mexico (GOM), above a shallow Arctic air mass ahead of a midlevel trough. Because the GOM is the proximal basin and major moisture source, this study investigates impacts of varying GOM sea surface temperature (SST) on the thermodynamic evolution of a winter storm that occurred during 28–30 January 2010, with particular emphasis on the modulation of freezing precipitation. A high-resolution, nested ARW sensitivity study with a 3.3-km inner domain is performed, using six representations of GOM SST, including control, climatological mean, uniform ±2°C from control, and physically constrained upper- and lower-bound basin-average anomalies from a 30-yr dataset. The simulations reveal discernable impacts of SST on the warm-layer inversion, precipitation intensity, and low-level dynamics. Whereas total precipitation for the storm increased monotonically with SST, the freezing-precipitation response was more varied and nonlinear, with the greatest accumulation decreases occurring for the coolest SST perturbation, particularly at moderate precipitation rates. Enhanced precipitation and warm-layer intensity promoted by warmer SST were offset for the highest perturbations by deepening of the weak 850-hPa low circulation and faster eastward progression associated with enhanced baroclinicity and diabatic generation of potential vorticity. Air-parcel trajectories terminating within the freezing-precipitation region were examined to identify airmass sources and modification. These results suggest that GOM SST can affect the severity of concurrent ice-storm events in the southern Great Plains, with warmer basin SST potentially exacerbating the risk of damaging ice accumulations.
Assessing Seasonality in the Surface Urban Heat Island of London
Authors: Zhou Bin , Lauwaet Dirk , Hooyberghs Hans , De Ridder Koen , Kropp Jürgen P. , Rybski Diego 
Published: November 2015

AbstractThis paper assesses the seasonality of the urban heat island (UHI) effect in the Greater London area (United Kingdom). Combining satellite-based observations and urban boundary layer climate modeling with the UrbClim model, the authors are able to address the seasonality of UHI intensity, on the basis of both land surface temperature (LST) and 2-m air temperature, for four individual times of the day (0130, 1030, 1330, and 2230 local time) and the daily means derived from them. An objective of this paper is to investigate whether the UHI intensities that are based on both quantities exhibit a similar hysteresis-like trajectory that is observed for LST when plotting the UHI intensity against the background temperature. The results show that the UrbClim model can satisfactorily reproduce both the observed urban–rural LSTs and 2-m air temperatures as well as their differences and the hysteresis in the surface UHI. The hysteresis-like seasonality is largely absent in both the observed and modeled 2-m air temperatures, however. A sensitivity simulation of the UHI intensity to incoming solar radiation suggests that the hysteresis of the LST can mainly be attributed to the seasonal variation in incoming solar radiation.
Tidal Mixing in the South China Sea: An Estimate Based on the Internal Tide Energetics
Authors: Wang Xiaowei , Peng Shiqiu , Liu Zhiyu , Huang Rui Xin , Qian Yu-Kun , Li Yineng 
Published: November 2015

AbstractBy taking into account the contributions of both locally and remotely generated internal tides, the tidal mixing in the Luzon Strait (LS) and the South China Sea (SCS) is investigated through internal-tide simulation and energetics analysis. A three-dimensional nonhydrostatic high-resolution model driven by four primary tidal constituents (M2, S2, K1, and O1) is used for the internal-tide simulation. The baroclinic energy budget analysis reveals that the internal tides radiated from the LS are the dominant energy source for the tidal dissipation in the SCS. In the LS, the estimated depth-integrated turbulent kinetic energy dissipation exceeds O(1) W m−2 atop the two subsurface ridges, with a dissipation rate of >O(10−7) W kg−1 and diapycnal diffusivity of ~O(10−2) m2 s−1. In the SCS, the most intense turbulence occurs in the deep-water basin with a dissipation rate of O(10−8–10−6) W kg−1 and diapycnal diffusivity of O(10−3–10−1) m2 s−1 within the ~2000-m water column above the seafloor as well as in the shelfbreak region with a dissipation rate of O(10−7–10−6) W kg−1 and diapycnal diffusivity of O(10−4–10−3) m2 s−1. These estimated values are consistent with observations reported in previous studies and are at least one order of magnitude larger than those based solely on locally generated internal tides.
Improving the assessment of depression remission with the Remission Evaluation and Mood Inventory Tool
Authors: Aikens James E , Klinkman Michael S , Sen Ananda , Nease Donald E 
Published: November 2015

Objective The Remission Evaluation and Mood Inventory Tool (REMIT) is a practical 5-item self-report measure of key positive mood states associated with recovering from depression, as distinct from depressive symptoms per se. The study goal was to identify a clinically useful threshold for interpreting REMIT responses in the context of mild to moderate depressive symptoms. Methods This was a secondary analysis of a cross-sectional dataset initially used to develop and validate the REMIT. Primary care patients being treated for depressive symptoms of either mild or moderate severity ( n = 247 and 240, respectively) rated their perceived degree of depression remission prior to completing the Patient Health Questionnaire-8 (PHQ-8) and the REMIT. We summed the totals of the latter two measures to form the PHQ + REMIT index. Results Receiver Operating Characteristics analysis indicated that the PHQ + REMIT threshold ≥13 was associated with good sensitivity (92%) and acceptable specificity (43%) to the absence of patient-perceived remission. In contrast, the PHQ had only 21% specificity at this sensitivity level. Area under the curve was 0.815 (95% C.I.: 0.765–0.865), which was significantly greater than that of the PHQ-8 alone (area under the curve = 0.745, 95% C.I.: 0.691–0.805, p(diff) = 0.0002). Threshold performance was unaffected by adjustment for demographic characteristics and variation in remission percentage. Compared with standard symptom-based classification, using the REMIT reclassified 27% of mildly symptomatic patients as remitted. Conclusions Using the REMIT with patients who have mild to moderate depressive symptoms improves the assessment of patient-perceived remission, which is indicated by a summed PHQ + REMIT index of less than 13. Longitudinal research is needed to test whether this broadened patient-centered approach to assessing remission improves clinical decision making and long-term outcomes.
Systematic Review of Endoscopic Obliteration Techniques for Managing Congenital Piriform Fossa Sinus Tracts in Children
Authors: Lachance Sophie , Chadha Neil K. 
Published: November 2015

BackgroundPiriform fossa sinus tracts (PFSTs) are a recognized cause of recurrent deep neck infections in the pediatric population. Conventional management has historically required open resection, but over recent years minimally invasive endoscopic approaches to obliterate the pharyngeal opening of the sinus have been performed in many centers. However, there is a lack of clear evidence regarding the success rate and safety of these approaches.ObjectiveTo determine the success rate of endoscopic management of PFST through a systematic review of the existing literature.Data SourcesMEDLINE (1964‐2014) and bibliographies of identified papers.Review MethodsTwo authors independently reviewed 170 abstracts and identified relevant studies for full‐text review. Data were independently extracted from those studies, and the Oxford Centre for Evidence‐Based Medicine guidelines were used to classify the level of evidence.ResultsThirteen studies met the inclusion criteria, comprising a total of 84 patients. All included studies were evidence level 4 (case series). Various methods of obliterating the PFST were described: electrocautery (n = 39), laser (n = 19), trichloroacetic acid (n = 19), silver nitrate (n = 4), combination of silver nitrate and laser (n = 2), and fibrin glue (n = 1). The success rate for endoscopic management of PFST was 89.3% overall (90.5% in primary cases and 85.7% in revision cases). The only adverse event reported was temporary vocal cord immobility in 2.4% (n = 2) of cases.ConclusionEndoscopic management of pediatric PFST appears to be safe and effective, as a primary option and for revision after open surgery.
IAPAC Guidelines for Optimizing the HIV Care Continuum for Adults and Adolescents
Authors:   International Advisory Panel on HIV Care Continuum Optimization
Published: November 2015

Background: An estimated 50% of people living with HIV (PLHIV) globally are unaware of their status. Among those who know their HIV status, many do not receive antiretroviral therapy (ART) in a timely manner, fail to remain engaged in care, or do not achieve sustained viral suppression. Barriers across the HIV care continuum prevent PLHIV from achieving the therapeutic and preventive effects of ART. Methods: A systematic literature search was conducted, and 6132 articles, including randomized controlled trials, observational studies with or without comparators, cross-sectional studies, and descriptive documents, met the inclusion criteria. Of these, 1047 articles were used to generate 36 recommendations to optimize the HIV care continuum for adults and adolescents. Recommendations: Recommendations are provided for interventions to optimize the HIV care environment; increase HIV testing and linkage to care, treatment coverage, retention in care, and viral suppression; and monitor the HIV care continuum.
India’s Diversity and Globalization: Unifying Forces and Innovation
Authors: Kaul Vijay Kumar 
Published: November 2015

India is a multilinguial, multireligious, and multi-caste country and has been a dominant player in the world system and part of the global economy for ages. Its civilizational past has been shaped and has evolved through a number of events, crises, people, and communities. It has not been an isolated country at any point of time, as there has been a continuous exchange of ideas, products, and people with other countries and civilizations. It therefore becomes essential to understand India in a global context to examine its problems and to seek solutions. There are two types of studies focusing on changes in society, its interlinkages with others, and global system: civilization studies and world-systems analysis. The scholars in the civilization studies have focused on identifying the existence of different civilizations in different geographical areas in the ancient period. Some have devoted more attention to the interrelations and mutual influences among civilizations in terms of culture and ideology, and their rise and decline through several stages. World-systems analysts, on the other hand, have developed a perspective to examine issues of capitalism, development, and world inequalities. The world economy is a system of interconnected national economies that bring together national financial power and states that struggle to move up the hierarchy of states in terms of power and wealth. Both these groups of studies have given insight to understand the existence and growth of countries in present forms. It therefore becomes imperative to look at the key findings of these studies to have better understanding of India’s socioeconomic and environmental problems. This article proposes that a good governance system can direct India’s diversity and socioeconomic challenges to develop an innovative society. Further, it attempts to examine the following questions: How has India evolved as a civilizational entity over a period of the last 2000 years? How has globalization influenced its evolution during the last few centuries? What are the unifying factors of India in terms of culture, constitutions, and social processes? What are the present and new challenges that have emerged during last 60–70 years? How is India, despite its diversity, meeting and solving such challenges? In view of growing trend of globalization, are the unifying forces still relevant or not?
The effect of donor characteristics on survival after unrelated donor transplantation for hematologic malignancy
Authors: Kollman Craig , Spellman Stephen R. , Zhang Mei-Jie , Hassebroek Anna , Anasetti Claudio , Antin Joseph H. , Champlin Richard E. , Confer Dennis L. , DiPersio John F. , Fernandez-Viña Marcelo , Hartzman Robert J. , Horowitz Mary M. , Hurley Carolyn K. , Karanes Chatchada , Maiers Martin , Mueller Carlheinz R. , Perales Miguel-Angel , Setterholm Michelle , Woolfrey Ann E. , Yu Neng , Eapen Mary 
Published: November 2015

Key PointsDonor age and donor-recipient HLA match predict survival after hematopoietic cell transplantation.
Double-Blind Phase III Randomized Trial of the Antiprogestin Agent Mifepristone in the Treatment of Unresectable Meningioma: SWOG S9005
Authors: Ji Yongli , Rankin Cathryn , Grunberg Steven , Sherrod Andy E. , Ahmadi Jamshid , Townsend Jeannette J. , Feun Lynn G. , Fredericks Ruth K. , Russell Christy A. , Kabbinavar Fairooz F. , Stelzer Keith J. , Schott Anne , Verschraegen Claire 
Published: November 2015

Purpose Progesterone receptors are expressed in approximately 70% of meningiomas. Mifepristone is an oral antiprogestational agent reported to have modest activity in a phase II study. This multicenter, prospective, randomized, placebo-controlled phase III trial conducted by SWOG was planned to define the role of mifepristone in the treatment of unresectable meningioma. Patients and Methods Eligible patients were randomly assigned to receive either mifepristone or placebo for 2 years unless disease progressed. Patients who were stable or responding to protocol therapy after 2 years had the option to continue with the same blinded therapy. Serial follow-up allowed assessment of efficacy and toxicity. Time to treatment failure and overall survival were ascertained for all randomly assigned patients. On progression, patients receiving placebo could cross over and receive active drug. Results Among 164 eligible patients, 80 were randomly assigned to mifepristone and 84 to placebo. Twenty-four patients (30%) were able to complete 2 years of mifepristone without disease progression, adverse effects, or other reasons for discontinuation. Twenty-eight patients (33%) in the placebo arm completed the 2-year study. There was no statistical difference between the arms in terms of failure-free or overall survival. Conclusion Long-term administration of mifepristone was well tolerated but had no impact on patients with unresectable meningioma.
Female Estrogen-Related Factors and Incidence of Basal Cell Carcinoma in a Nationwide US Cohort
Authors: Cahoon Elizabeth K. , Kitahara Cari M. , Ntowe Estelle , Bowen Emily M. , Doody Michele M. , Alexander Bruce H. , Lee Terrence , Little Mark P. , Linet Martha S. , Freedman D. Michal 
Published: November 2015

Purpose UV radiation exposure is the primary risk factor for basal cell carcinoma (BCC), the most common human malignancy. Although the photosensitizing properties of estrogens have been recognized for decades, few studies have examined the relationship between reproductive factors or exogenous estrogen use and BCC. Methods Using data from the US Radiologic Technologists Study, a large, nationwide, prospective cohort, we assessed the relationship between reproductive factors, exogenous estrogen use, and first primary BCC while accounting for sun exposure, personal sun sensitivity, and lifestyle factors for geographically dispersed women exposed to a wide range of ambient UV radiation. Results Elevated risk of BCC was associated with late age at natural menopause (hazard ratio [HR] for ≥ 55 years v 50 to 54 years, 1.50; 95% CI, 1.04 to 2.17) and any use of menopausal hormone therapy (MHT; HR, 1.16; 95% CI, 1.03 to 1.30; P for trend for duration = .001). BCC risk was most increased among women reporting natural menopause who used MHT for 10 or more years versus women who never used MHT (HR, 1.97; 95% CI, 1.35 to 2.87). Risk of BCC was not associated with age at menarche, parity, age at first birth, infertility, use of diethylstilbestrol by participant's mother, age at hysterectomy, or use of oral contraceptives. Conclusion These analyses confirm a previous finding of increased risk of BCC associated with MHT. Novel findings of increased BCC risk associated with MHT in women experiencing natural menopause and for late age at natural menopause warrant further investigation. Users of MHT may constitute an additional high-risk group in need of more frequent skin cancer screening.
Cerebral Perfusion and Gray Matter Changes Associated With Chemotherapy-Induced Peripheral Neuropathy
Authors: Nudelman Kelly N.H. , McDonald Brenna C. , Wang Yang , Smith Dori J. , West John D. , O'Neill Darren P. , Zanville Noah R. , Champion Victoria L. , Schneider Bryan P. , Saykin Andrew J. 
Published: November 2015

Purpose To investigate the longitudinal relationship between chemotherapy-induced peripheral neuropathy (CIPN) symptoms (sx) and brain perfusion changes in patients with breast cancer. Interaction of CIPN-sx perfusion effects with known chemotherapy-associated gray matter density decrease was also assessed to elucidate the relationship between CIPN and previously reported cancer treatment–related brain structural changes. Methods Patients with breast cancer treated with (n = 24) or without (n = 23) chemotherapy underwent clinical examination and brain magnetic resonance imaging at the following three time points: before treatment (baseline), 1 month after treatment completion, and 1 year after the 1-month assessment. CIPN-sx were evaluated with the self-reported Functional Assessment of Cancer Therapy/Gynecologic Oncology Group–Neurotoxicity four-item sensory-specific scale. Perfusion and gray matter density were assessed using voxel-based pulsed arterial spin labeling and morphometric analyses and tested for association with CIPN-sx in the patients who received chemotherapy. Results Patients who received chemotherapy reported significantly increased CIPN-sx from baseline to 1 month, with partial recovery by 1 year (P < .001). CIPN-sx increase from baseline to 1 month was significantly greater for patients who received chemotherapy compared with those who did not (P = .001). At 1 month, neuroimaging showed that for the group that received chemotherapy, CIPN-sx were positively associated with cerebral perfusion in the right superior frontal gyrus and cingulate gyrus, regions associated with pain processing (P < .001). Longitudinal magnetic resonance imaging analysis in the group receiving chemotherapy indicated that CIPN-sx and associated perfusion changes from baseline to 1 month were also positively correlated with gray matter density change (P < .005). Conclusion Peripheral neuropathy symptoms after systemic chemotherapy for breast cancer are associated with changes in cerebral perfusion and gray matter. The specific mechanisms warrant further investigation given the potential diagnostic and therapeutic implications.