bluuebunny/crossref_metadata_2025_split huggingface dataset:
European Colorectal Cancer Management: Implemented as it is or Adapted to our National Specificity
Authors: Dobre A , Hintea A , Azamfirei L 
Published: August 2015

Abstract

Objective: We attempt to evaluate how the European treatment guides are implemented in a clinic hospital in Targu Mures and if those rules could be adopted as they are or must be adapted to our national specificity.

Methods: For a number of 441 patients included in the study, the electronic prospectively maintained archive of 3rd Surgery was interrogated for: age, preoperative colonoscopy, postoperative colonoscopies, chemo-radiotherapy enrollment, stage of the disease, type of surgery. Local and regional relapses were assessed and their incidence was related to type of surgery. Survival analysis was done in a simplified manner and differentiated for age below and above 75 years.

Results: Patient’s age distribution revealed a deviation to the right compared with a normal distribution with a median off 64.76±11.47. Colonoscopy was done in only 65 cases, exclusive preoperatively. Chemoradiotherapy was administered in 168 cases, only 12 of them initiated preoperatively. The type of surgery performed was found positively correlate with the stage of the disease. The survival probability for the patients in this study showed a 50% survival rate at 1 year and only 2% at 5 years.

Conclusions: Passive screening age in CRC should be decreased to 55 years. Stage 3 and 4 of disease for CRC are over 70% of cases, like 20 years ago. Survival rate in CRC is far lower than other studies. Integrated CRC management and European practical guides are still “in wishing” stage.
Socio-demographic Characteristics of Patients Diagnosed with Advanced Chronic Venous Insufficiency (C4-C6) Correlated with Clinical and Para-clinical Findings
Authors: Reka Imre Eniko , Imre M 
Published: August 2015

Abstract
Chronic venous insufficiency’s frequency reaches almost 25% in European countries. The aim of this present study was to assess the correlation between sociodemographic characteristics as well as clinical findings and para-clinical findings of aCVI patients. A total number of 2636 patients diagnosed with CVI were evaluated for over an 8 year time period (2006-2013). In case of 795 of them, diagnosis of aCVI (C4-C6) has been established. The following variables have been evaluated: demographic data, etiology, risk factors, chronic diseases as risk factors, signs and symptoms, laboratory findings and even the therapeutic approach. All the assessed data has been evaluated using descriptive statistics, t-Student test, and chi square test. Also the relative risk (RR) and Odds ratio (OR) has been calculated. The mean age of aCVI patients was significantly higher (p=0.001) than the age of patients with stage C1-3 CVI. A positive correlation (p<0.0001) between combined venous disorders and clinical stage of CVI has been found. Deep vein thrombosis proved to be correlated (p=0.02) with evolution of CVI to venous ulcer (stage C6). Worsening of advanced venous insufficiency was also correlated with presence of peripheral arterial diseases, and/or metabolic diseases (p<0.0001, and p=0.02). Based on our results, the typical profile of a patient with aCVI has been outlined. Using this profile, the general practitioner and even the internal medicine specialist can recognize in advance patients with an elevated risk of developing aCVI, and accordingly can choose a more appropriate therapeutic approach.
Pancreatico-Gastric Anastomosis with and without Sutures – Experimental Swine Model
Authors: Tudor A , Molnar C , Copotoiu C , Butiurca VO , Nicolescu C , Bianca Tudor , Simona Gurzu 
Published: August 2015

Abstract

Objectives. The aim of our study is to identify a surgical technical that has the lowest rate of pancreatic fistulas in pancreatico-gastric anastomosis following duodenopancreatectomies. We studied pancreatico-gastric anastomosis performed with stitches compared to the ones performed without stitches.

Methods. Our experimental model is based on ten piglets, which were divided into 2 groups. In the first group (n=5) the pancreatico-gastric anastomosis was done using double purse-string threads one passed through the gastric seromuscular layer and one through the gastric mucosa. In the second group (n=5) the pancreatico-gastric anastomosis was performed using sutures through the stomach and pancreas.

Results. Postoperative amylasemia was higher in the second group. In the first group no pancreatico-gastric fistulas were observed, whereas pancreatic necrosis was observed only at a superficial level of the pancreatic stump. In the second group, two cases had developed fistulas, both bordered by large areas of coagulation necrosis accompanied by pancreatic duct hyperplasia. Duration of the anastomosis was shorter for the first group.

Conclusions. In conclusion, the pancreatico-gastric anastomosis performed using two purse-string suture is a feasible, safe and fast process.
The Effect of Sex on the Dressing Percentage, Carcass, and Organ Quality in the Fallow Deer (Dama Dama)
Authors: Stanisz Marek , Ludwiczak Agnieszka , Buda Przemysław , Pietrzak Marian , Bykowska Marta , Kryza Artur , Ślósarz Piotr 
Published: August 2015

Abstract
Basic carcass characteristics, the quality traits of meat and internal organs from 10 fallow deer bucks and 10 does aged from 31 to 32 months were investigated. No sex effects on the bled body weight, meat yield and carcass composition were found. A significantly higher weight of mesenteric and omental fat (by 0.44 kg) was found for does. The combined share of muscle and fat in the carcass parts ranged from 77.9 to 78.5%, and the share of bones from 21.5 to 22.1%. No sex effects were found for the pH and water holding capacity measurements. Venison from males was characterized by a significantly higher thermal drip value (P=0.043) and higher L* (P=0.026), a* (P=0.010) and b* (P=0.036) values compared to does. The extracted fat content was significantly higher for females compared to males (P=0.009). The chemical analysis of deer edible by-products indicated the highest level of protein for the liver (17%), and the highest level of dry matter and fat for the tongue (33-34% and 15-18%, respectively).
The Relation Between Intramuscular Fat Level in the Longissimus Muscle and the Quality of Pig Carcasses and Meat
Authors: Pietruszka Arkadiusz , Jacyno Eugenia , Kawęcka Maria , Biel Wioletta 
Published: August 2015

Abstract
This study evaluated the effect of intramuscular fat (IMF) content on the quality of pig carcass and meat. One hundred and twenty right half-carcasses of crossbred pigs (Pietrain × Duroc boars and Polish Large White × Polish Landrace sows) from a commercial farm were divided into two groups depending on the content of IMF in the longissimus muscle (LM): LIMF - lower content (mean 2.05% IMF; 28 gilts and 30 barrows) and HIMF - higher content (mean 3.08% IMF; 32 gilts and 30 barrows) were used. Pigs with a higher IMF content in LM (HIMF group) had a significantly lower (P≤0.01) percentage of lean meat in carcass, loin muscle area, level of polyunsaturated fatty acids (PUFAs) and PUFAs/SFAs ratio, whereas backfat thickness, content of cholesterol in LM, levels of saturated fatty acids (SFAs) and monounsaturated fatty acids (MUFAs) were significantly greater (P≤0.01) than those in pigs with lower IMF content (LIMF group).
Fast-Growing Energy Crops Grown In Conditions Of Slovakia In The Context Of The EU Energy Policy
Authors: Jureková Zuzana , Kotrla Marián , Prčík Martin , Hauptvogl Martin , Pauková Žaneta 
Published: August 2015

Abstract
The energy-efficient low-carbon EU economy (known as the 20-20-20) sets fundamental objectives in reducing greenhouse gas emissions (20%), increasing the share of renewable energy sources (20%) and saving primary energy consumption (20%). The objectives are incorporated in the National Renewable Energy Action Plans (NREAPs). Slovakia has to increase the share of renewable energy sources (RES) by 14% in its energy mix by 2020. Currently, the most widely used RES are water and solar energy, biomass and biogas. Our country has suitable ecological conditions for growing the so called energy crops in lowland and upland areas. So far, however, there is a lack of science-based information on the potential production of biomass in different soil-ecological and climatic conditions of the Slovak Republic. Our experimental research is focused on quantification of biomass production of various willow (genus Salix), poplar (genus Populus) and silvergrass (Miscanthus sinensis) varieties grown in ecological conditions of southern Slovakia. We evaluated the biomass production of the studied crops. The results were evaluated in terms of the EU call (2013): to obtain more energy while reducing inputs and negative environmental impacts.
Social Aspects Of Rural Community Development
Authors: Majerová Věra 
Published: August 2015

Abstract
A well-balanced relationship between economic and social progress is the main prerequisite of rural community stability. Economic development is influenced by many factors. Some of these are statistically discoverable and quantifiable, while others, which fall within the sphere of social relations and their identification, are more difficult to measure and interpret. Czech rural areas face many problems which arise from their specific features – socio-demographic structure, job possibility of various social groups, provision of the proper level of public services, transport accessibility, etc. However, there is no direct connection between economic factors and mutual relations within the rural community. Values, opinions and the behavioural patterns of people are immediately displayed in a locality, but their character is shaped by the regional and national assumptions of every stage of development. Contributions are drawn from the accessible literature and secondary data of empirical research projects.
Socio-Economic Importance Of Associated Plant Species In Short Rotation Coppice Plantations
Authors: Beniak Michal , Žabka Michal 
Published: August 2015

Abstract
Many ecosystem services do not pass through markets. Therefore, the benefits which ecosystems provide to society are largely unrecorded. Fast-growing woody crops represent a quite new and still insufficiently explored ecosystem of agricultural land which has a potential to provide several utility functions. It may contribute to satisfaction of human needs and may enhance regional health. The goal of this paper was to detect the socio-economic importance of associated spontaneous vegetation in plantations of the energy crops (hybrids of the genera Salix) and to compare it with the socio-economic importance of adjacent permanently cultivated agricultural field. There was examined the therapeutic, melliferous, feed, allergenic and toxic potential of undergrowth for each experimental plot inside the SRC plantations. The research was carried out on the agricultural land formerly used for growing cereals and root crops – the research base Kolíňany. Our results showed that energy plantation understoreys can be assumed to be the better option for contribution to the total socio-economic value of a region than agricultural fields.
Obesity and fertility
Authors: Best Damian , Bhattacharya Siladitya 
Published: August 2015

Abstract
The prevalence of overweight and obesity in women of reproductive age has increased over the past 30 years. Infertility affects 1 in 7 couples, and female obesity is associated with anovulation. The mechanisms by which excessive fat delays time to pregnancy (TTP) appear rooted in ovulatory problems and direct effects on oocytes, causing poorer embryo development, as well as in effects on the endometrium. Weight loss in women has been shown to improve conception, but not necessarily live birth rates following fertility treatment, and further research in this area is needed. The obesity epidemic has been accompanied by a potential rise in male infertility, which has been attributed to hormonal disturbances and compromised semen parameters.
Preparation of Nano-curcumin with Enhanced Dissolution Using Ultrasonic-Assisted Supercritical Anti-solvent Technique
Authors: Zabihi Fatemeh , Xin Na , Jia Jingfu , Cheng Tao , Zhao Yaping 
Published: August 2015

Abstract
Curcumin is the main gradient of “Turmeric” a famous Indian spice and food additive. The marvelous nutritional and medicinal effects of curcumin made it a good alternative to some conventional drugs and food flavoring or coloring materials. However, the low solubility of curcumin is a challenging hindrance which should be seriously addressed. In this work, we prepared nano-curcumin with enhanced aqueous dispersion and dissolution rate. Ultrasonic-assisted supercritical anti-solvent (UA-SAS) technique was used to convert the commercial curcumin to uniform distributed nano-particles with the average size of 20 nm and yielding of 65%. The effect of process parameters including pressure, temperature, solution flow rate, and nature of organic solvent on the average particle size and yielding of products was investigated. The morphology, size, and crystalline pattern of processed curcumin particles were characterized by scanning electron microscopy, mean particle size analyzer, and X-ray diffraction. The champion specimen was achieved when the supercritical fluid was employed at 16 MPa and 35°C. Aqueous suspension of processed nano-curcumin can be stable for more than 2 months. In vitro dissolution experiments showed a remarkable enhancement in dissolution rate of UA-SAS-treated curcumin respecting to the commercial curcumin powder.
New Targets for End-Stage Chronic Kidney Disease Therapy
Authors: Prakoura Niki , Kavvadas Panos , Chatziantoniou Christos 
Published: August 2015

Abstract
Severe forms of chronic kidney disease can lead to a critical, end-stage condition, requiring renal replacement therapy, which may involve a form of dialysis or renal transplantation. Identification and characterization of novel markers and/or targets of therapy that could be applied in these critically ill patients remains the focus of the current research in the field of critical care medicine and has been the objective of our studies for some years past. To this end, we used models of renal vascular disease, Ang II, L-NAME or mice overexpressing renin, treated with AT1 antagonists at different stages of progression, to create cohorts of animals during progression, reversal or escape from therapy. Transcriptomic analysis and comparisons were performed and genes were selected according to the following criteria: a) not previously described in the kidney, b) highly upregulated during progression and returning to the normal levels during reversal, and c) producing proteins that are either circulating or membrane receptors.
The involvement of the selected genes in the mechanisms of renal disease was confirmed in additional models of renal disease, initiated in other compartments of the kidney such as glomeruli (administration of nephrotoxic serum) or the tubular interstitium (unilateral ureteral obstruction). The potential of the therapy was tested using mice lacking the expression of these genes and by in vivo administration of antisense oligonucleotides which blocked the transcription of the targeted genes. This strategy allowed the identification of periostin, an extracellular matrix protein normally involved in bone and tooth development, in addition to the discoidin domain receptor1 (DDR1) as potential targets of therapy against renal inflammation and fibrosis.
Levels of natural radioactivity in mineral and thermal waters of Bosnia and Herzegovina
Authors: Kasić Amela , Adrović Feriz , Kasumović Amira , Hankić Ema 
Published: August 2015

Abstract
With gamma spectrometric method 23 samples of mineral and thermal waters of Bosnia and Herzegovina were analyzed. Activity concentrations of the investigated radionuclides were in the range 12–346 mBq·L−1 for 40K, 1.1–791 mBq·L−1 for 226Ra, 0.2–221 mBq·L−1 for 228Ra, 13–367 mBq·L−1 for 238U, and 0.6–17 mBq·L−1 for 235U. For all investigated radionuclides annual effective dose was estimated. The estimated total annual committed effective dose received by population as a result of ingestion of water was in the range 0.11–2.51 μSv·y−1 for thermal water and in the range 0.11–38.8 μSv·y−1 for mineral water. Measurement of activity concentrations of natural radionuclides in the examined samples was carried out with a gamma-spectrometer with high-purity germanium (HPGe) detector, having a relative efficiency of 70%.
Synthesis and evaluation of radiolabeled, folic acid-PEG conjugated, amino silane coated magnetic nanoparticles in tumor bearing Balb/C mice
Authors: Razjouyan Javad , Zolata Hamidreza , Khayat Omid , Nowshiravan Fereidoun , Shadanpour Nami , Mohammadnia Meisam 
Published: August 2015

Abstract
To design a potent agent for positron emission tomography/magnetic resonance imaging (PET/MRI) imaging and targeted magnetic hyperthermia-radioisotope cancer therapy radiolabeled surface modified superparamagnetic iron oxide nanoparticles (SPIONs) were used as nanocarriers. Folic acid was conjugated for increasing selective cellular binding and internalization through receptor-mediated endocytosis. SPIONs were synthesized by the thermal decomposition of tris (acetylacetonato) iron (III) to achieve narrow and uniform nanoparticles. To increase the biocompatibility of SPIONs, they were coated with (3-aminopropyl) triethoxysilane (APTES), and then conjugated with synthesized folic acid-polyethylene glycol (FA-PEG) through amine group of (3-aminopropyl) triethoxysilane. Finally, the particles were labeled with 64Cu (t
1/2 = 12.7 h) using 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid mono (N-hydroxy succinimide ester) DOTA-NHS chelator. After the characterization of SPIONs, their cellular internalization was evaluated in folate receptor (FR) overexpressing KB (established from a HeLa cell contamination) and mouse fibroblast cell (MFB) lines. Eventually, active and passive targeting effects of complex were assessed in KB tumor-bearing Balb/C mice through biodistribution studies. Synthesized bare SPIONs had low toxicity effect on healthy cells, but surface modification increased their biocompatibility. Moreover, KB cells viability was reduced when using folate conjugated SPIONs due to FR-mediated endocytosis, while having little effect on healthy cells (MFB). Moreover, this radiotracer had tolerable in vivo characteristics and tumor uptake. In the receptor blocked case, tumor uptake was decreased, indicating FR-specific uptake in tumor tissue while enhanced permeability and retention effect was major mechanism for tumor uptake.
EMR-related problems at the interface between the crystal field Hamiltonians and the zero-field splitting Hamiltonians
Authors: Rudowicz Czesław , Karbowiak Mirosław 
Published: August 2015

Abstract
The interface between optical spectroscopy, electron magnetic resonance (EMR), and magnetism of transition ions forms the intricate web of interrelated notions. Major notions are the physical Hamiltonians, which include the crystal field (CF) (or equivalently ligand field (LF)) Hamiltonians, and the effective spin Hamiltonians (SH), which include the zero-field splitting (ZFS) Hamiltonians as well as to a certain extent also the notion of magnetic anisotropy (MA). Survey of recent literature has revealed that this interface, denoted CF (LF) ↔ SH (ZFS), has become dangerously entangled over the years. The same notion is referred to by three names that are not synonymous: CF (LF), SH (ZFS), and MA. In view of the strong need for systematization of nomenclature aimed at bringing order to the multitude of different Hamiltonians and the associated quantities, we have embarked on this systematization. In this article, we do an overview of our efforts aimed at providing a deeper understanding of the major intricacies occurring at the CF (LF) ↔ SH (ZFS) interface with the focus on the EMR-related problems for transition ions.
EMR study and superposition model analysis of Cr3+ and Fe3+ impurity ions in mullite powders used in aerospace industry
Authors: Stefaniuk Ireneusz , Rogalska Iwona 
Published: August 2015

Abstract
In this work, the electron magnetic resonance (EMR) spectra of the mullites powders were measured for different grain sizes (0.07 and 0.12 mm). We have used EMR spectroscopy at X-band, combined with superposition model (SPM) calculations to reveal electronic structure and establish correlations between structure, and surroundings of these complexes.
The MAS NMR study of solid solutions based on the YAG crystal
Authors: Padlyak Bohdan V. , Sergeev Nikolaj A. , Olszewski Marcin , Stępień Piotr 
Published: August 2015

Abstract
An 27Al magic angle spinning (MAS) nuclear magnetic resonance (NMR) study of nominally pure and Cr-doped yttrium-aluminum garnet (Y3Al5O12 and Y3Al5O12:Cr) crystals is reported. It has been shown that the doping by Cr of the Y3Al5O12 crystals leads to the variation of the occupation by Al atoms both octahedrally and tetrahedrally coordinated sites of the garnet lattice.
Magnetic transformation in Ni-Mn-In Heusler alloy
Authors: Kuzma Marian , Maziarz Wojciech , Stefaniuk Ireneusz 
Published: August 2015

Abstract
Magnetic properties of a Ni50Mn35.5In14.5 Heusler ribbon were studied by ferromagnetic resonance (FMR) in the temperature range of 335–100 K. In the temperature region of 265–170 K, the FMR signal disappeared, in spite of the fact that this region comprised the main crystal transformation temperatures: Ms
, Mf
, As
, Af
. In the austenite crystal state, a weak antiferromagnetic interaction was observed, whereas ferromagnetism was detected in the low temperature martensitic state.
Impact of humic acids on EYL liposome membranes: ESR method
Authors: Pytel Barbara , Filipiak Aneta , Pisarek Izabella , Olchawa Ryszard , Man Dariusz 
Published: August 2015

Abstract
In this paper, the effects of model (commercial) and natural (extracted from peat) humic substances on the membrane of liposomes formed with egg yolk lecithin (EYL) are presented. In our research, mass concentrations of fulvic and humic acids were used, which in relation to lecithin varied from 0% to 13%. To study membrane fluidity, electron spin resonance (EPR) was used with two spin probes, penetrating various regions of the lipid bilayer. The effects of model and natural humic substances (humic acids – HAs and fulvic acids – FAs) on the lipid membrane in different regions were researched: the lipid-water interphase, and in the middle of the lipid bilayer. It was shown that FA and HA impact the fluidity of liposome membranes in different ways. Increased mass concentrations of HAs decreased membrane fluidity in both acids: extracted from peat and the model. However, increased mass concentration of FAs extracted from peat, decreased membrane fluidity in the surface region, at the same time stiffening the central part of the bilayer. Increasing the concentration of FAs extracted from peat had the opposite effect when compared to model FA. This effect may be related to the complexation of xenobiotics present in the soil environment and their impact on biological membranes.
Oxidative stability of the lipid fraction in cookies – the EPR study
Authors: Zawada Katarzyna , Kozłowska Mariola , Żbikowska Anna 
Published: August 2015

Abstract
Cookies are a group of convenient food products that are popular among consumers. They may contain high amounts of fats, which can be prone to oxidation. To retard the oxidative deterioration, synthetic and natural antioxidants may be added. Herb and spice extracts can be sources of natural biologically active substances with antioxidant activity. In this work, electron paramagnetic resonance spectroscopy was used to monitor the lipid oxidation in cookies with rosemary and thyme extracts subjected to the storage in elevated temperature. It was shown that thyme extract can be used as a natural antioxidant source for the preparation of bakery products, while the rosemary extract should be used with care in fat-rich products exposed to high temperatures.