bluuebunny/crossref_metadata_2025_split huggingface dataset:
Family level classification within Thylacocephala, with comments on their evolution and possible relationships
Authors: Schram Frederick R. 
Published: April 2014

Thylacocephala are among the most problematic of arthropod fossils. Various authors have allied them with all manner of crustacean groups, including branchiopods, cirripedes, remipedes, and malacostracans. They have a very apomorphic body plan often marked by hypertrophy of the compound eyes, three pairs of large raptorial subchelate limbs, eight sets of well-developed phyllobranch gills, and from 8 to at least 16 posterior trunk somites bearing paddle-like limbs. They have been thought of as a distinct class composed of two orders, Concavicarida and Conchyliocarida, but membership within the orders varies according to authors, and no familial divisions have been proposed within the orders until now. This lack of taxonomic structure inhibits organization of available information concerning the paleoecology, paleogeography, and phylogenetic relationships of thylacocephalans. A working hypothesis for the higher taxonomy within the class is proposed here. This entails a redefinition of the two orders, and recognition of seven families, five of them new: Austriocarididae Glaessner, 1931, Clausocarididae Arduini, 1992 (new status), Concavicarididae n. fam., Dollocarididae, n. fam., Microcarididae n. fam., Ostenocarididae n. fam. and Protozoeidae n. fam.
Rochinia hystrix (Stimpson, 1871) in the southwestern Atlantic, with morphological comparison to the partially sympatric congener Rochinia tanneri (Smith, 1883) (Brachyura, Epialtidae)
Authors: Pettan Renata B. , Tavares Marcos 
Published: April 2014

Rochinia hystrix(Stimpson, 1871) is reported herein for the first time from the southwestern Atlantic (Canopus Bank, off the coast of Ceará, Brazil, between 240 and 260 m). This species was previously known from the eastern Gulf of Mexico and the Caribbean Sea (Antilles), between 150 and 708 m.Rochinia hystrixand immatures ofR. tanneri(Smith, 1883) resemble each other and their geographical and bathymetric ranges partially overlap, so that morphological criteria are herein provided to distinguish between the two species. The opportunity is also taken to elaborate on the status of the type material ofR. tanneri.
Rediscovery of Lophiodes triradiatus (Lloyd, 1909), a senior synonym of L. infrabrunneus Smith and Radcliffe (Lophiiformes: Lophiidae)
Authors: HO HSUAN-CHING , BINEESH K. K. , AKHILESH K. V. 
Published: April 2014

Examination of the holotype and three recently collected additional specimens from the Indian Ocean has revealed that Lophius triradiatus Lloyd, 1909 (now under Lophiodes) is a valid species and a senior synonym of Lophiodes infrabrunneus Smith & Radcliffe, 1912 and Lophiodes abdituspinus Ni, Wu & Li, 1990. A detailed description of the additional specimens is provided.
African Climate Change Uncertainty in Perturbed Physics Ensembles: Implications of Global Warming to 4°C and Beyond*
Authors: James Rachel , Washington Richard , Rowell David P. 
Published: April 2014

Abstract
The importance of investigating regional climate changes associated with degrees of global warming is increasingly being recognized, but the majority of relevant research has been based on multimodel ensembles (MMEs) from the Coupled Model Intercomparison Project (CMIP). This has left two important questions unanswered: Are there plausible futures which are not represented by the models in CMIP? And, how would regional climates evolve under enhanced global warming, beyond 4°C? In this paper, two perturbed physics ensembles (PPEs) are used to address these issues with reference to African precipitation. Examination of model versions that generate warming greater than 4°C in the twenty-first century shows that changes in African precipitation are enhanced gradually, even to high global temperatures; however, there may be nonlinearities that are not incorporated here due to limited model complexity. The range of projections from the PPEs is compared to data from phases 3 and 5 of CMIP (CMIP3 and CMIP5), revealing regional differences. This is partly the result of implausible model versions, but the PPE dataset can be justifiably constrained given its size and systematic nature, highlighting an additional advantage over MMEs. After applying constraints, the PPEs still show changes that are outside the range of CMIP, most prominently strong dry signals in west equatorial Africa and the Sahel, implying that MMEs may underestimate risks for these regions. Analysis of African precipitation changes therefore demonstrates that regional assessments that rely on CMIP3 and CMIP5 may overlook uncertainties associated with model parameterizations and pronounced warming. More systematic approaches are needed for conservative estimates of danger.
Intense Precipitation Events Associated with Landfalling Tropical Cyclones in Response to a Warmer Climate and Increased CO2
Authors: Scoccimarro Enrico , Gualdi Silvio , Villarini Gabriele , Vecchi Gabriel A. , Zhao Ming , Walsh Kevin , Navarra Antonio 
Published: April 2014

Abstract
In this work the authors investigate possible changes in the intensity of rainfall events associated with tropical cyclones (TCs) under idealized forcing scenarios, including a uniformly warmer climate, with a special focus on landfalling storms. A new set of experiments designed within the U.S. Climate Variability and Predictability (CLIVAR) Hurricane Working Group allows disentangling the relative role of changes in atmospheric carbon dioxide from that played by sea surface temperature (SST) in changing the amount of precipitation associated with TCs in a warmer world. Compared to the present-day simulation, an increase in TC precipitation was found under the scenarios involving SST increases. On the other hand, in a CO2-doubling-only scenario, the changes in TC rainfall are small and it was found that, on average, TC rainfall tends to decrease compared to the present-day climate. The results of this study highlight the contribution of landfalling TCs to the projected increase in the precipitation changes affecting the tropical coastal regions.
Objectively Determined Fair-Weather NBL Features in ARW-WRF and Their Comparison to CASES-97 Observations
Authors: LeMone Margaret A. , Tewari Mukul , Chen Fei , Dudhia Jimy 
Published: April 2014

AbstractHeights of nocturnal boundary layer (NBL) features are determined using vertical profiles from the Advanced Research Weather Research and Forecasting Model (ARW-WRF), and then compared to data for three moderately windy fair-weather nights during the April–May 1997 Kansas-based Cooperative Atmosphere–Surface Exchange Study (CASES-97) to evaluate the success of four PBL schemes in replicating observations. The schemes are Bougeault–LaCarrere (BouLac), Mellor–Yamada–Janjić (MYJ), quasi-normal scale elimination (QNSE), and Yonsei University (YSU) versions 3.2 and 3.4.1. This study’s chosen objectively determined model NBL height h estimate uses a turbulence kinetic energy (TKE) threshold equal to 5% , where TKE′ is relative to its background (free atmosphere) value. The YSU- and MYJ-determined h could not be improved upon. Observed heights of the virtual temperature maximum hTvmax and wind speed maximum hSmax, and the heights h1wsonde and h2wsonde, between which the radiosonde slows from ~5 to ~3 m s−1 as it rises from turbulent to nonturbulent air, and thus brackets h, were used for comparison to model results. The observations revealed a general pattern: hTvmax increased through the night, and hTvmax and hSmax converged with time, and the two mostly lay between h1wsonde and h2wsonde after several hours. Clear failure to adhere to this pattern and large excursions from observations or other PBL schemes revealed excess mixing for BouLac and YSU version 3.2 (but not version 3.4.1) and excess thermal mixing for QNSE under windy conditions. Observed friction velocity was much smaller than model values, with differences consistent with the observations reflecting local skin drag and the model reflecting regional form drag + skin drag.
Extreme Quantitative Precipitation Forecast Performance at the Weather Prediction Center from 2001 to 2011
Authors: Sukovich Ellen M. , Ralph F. Martin , Barthold Faye E. , Reynolds David W. , Novak David R. 
Published: April 2014

Abstract
Extreme quantitative precipitation forecast (QPF) performance is baselined and analyzed by NOAA’s Hydrometeorology Testbed (HMT) using 11 yr of 32-km gridded QPFs from NCEP’s Weather Prediction Center (WPC). The analysis uses regional extreme precipitation thresholds, quantitatively defined as the 99th and 99.9th percentile precipitation values of all wet-site days from 2001 to 2011 for each River Forecast Center (RFC) region, to evaluate QPF performance at multiple lead times. Five verification metrics are used: probability of detection (POD), false alarm ratio (FAR), critical success index (CSI), frequency bias, and conditional mean absolute error (MAEcond). Results indicate that extreme QPFs have incrementally improved in forecast accuracy over the 11-yr period. Seasonal extreme QPFs show the highest skill during winter and the lowest skill during summer, although an increase in QPF skill is observed during September, most likely due to landfalling tropical systems. Seasonal extreme QPF skill decreases with increased lead time. Extreme QPF skill is higher over the western and northeastern RFCs and is lower over the central and southeastern RFC regions, likely due to the preponderance of convective events in the central and southeastern regions. This study extends the NOAA HMT study of regional extreme QPF performance in the western United States to include the contiguous United States and applies the regional assessment recommended therein. The method and framework applied here are readily applied to any gridded QPF dataset to define and verify extreme precipitation events.
Evaluation of Tropical Intraseasonal Variability and Moist Processes in the NOGAPS Analysis and Short-Term Forecasts
Authors: Li Weiwei , Wang Zhuo , Peng Melinda S. , Ridout James A. 
Published: April 2014

Abstract
Navy Operational Global Atmospheric Prediction System (NOGAPS) analysis and operational forecasts are evaluated against the Interim ECMWF Re-Analysis (ERA-Interim; ERAI) and satellite data, and compared with the Global Forecast System (GFS) analysis and forecasts, using both performance- and physics-based metrics. The NOGAPS analysis captures realistic Madden–Julian oscillation (MJO) signals in the dynamic fields and the low-level premoistening leading to active convection, but the MJO signals in the relative humidity (RH) and diabatic heating rate (Q1) fields are weaker than those in the ERAI or the GFS analysis. The NOGAPS forecasts, similar to the GFS forecasts, have relatively low prediction skill for the MJO when the MJO initiates over the Indian Ocean and when active convection is over the Maritime Continent. The NOGAPS short-term precipitation forecasts are broadly consistent with the Climate Prediction Center (CPC) morphing technique (CMORPH) precipitation results with regionally quantitative differences. Further evaluation of the precipitation and column water vapor (CWV) indicates that heavy precipitation develops too early in the NOGAPS forecasts in terms of the CWV, and the NOGAPS forecasts show a dry bias in the CWV increasing with forecast lead time. The NOGAPS underpredicts light and moderate-to-heavy precipitation but overpredicts extremely heavy rainfall. The vertical profiles of RH and Q1 reveal a dry bias within the marine boundary layer and a moist bias above. The shallow heating mode is found to be missing for CWV &lt; 50 mm in the NOGAPS forecasts. The diabatic heating biases are associated with weaker trade winds, weaker Hadley and Walker circulations over the Pacific, and weaker cross-equatorial flow over the Indian Ocean in the NOGAPS forecasts.
Transcription of the three HMG-CoA reductase genes of Mucor circinelloides
Authors: Nagy Gábor , Farkas Anita , Csernetics Árpád , Bencsik Ottó , Szekeres András , Nyilasi Ildikó , Vágvölgyi Csaba , Papp Tamás 
Published: April 2014

Abstract

Background
Precursors of sterols, carotenoids, the prenyl groups of several proteins and other terpenoid compounds are synthesised via the acetate-mevalonate pathway. One of the key enzyme of this pathway is the 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase, which catalyses the conversion of HMG-CoA to mevalonate. HMG-CoA reductase therefore affects many biological processes, such as morphogenesis, synthesis of different metabolites or adaptation to environmental changes. In this study, transcription of the three HMG-CoA reductase genes (designated as hmgR1, hmgR2 and hmgR3) of the β-carotene producing Mucor circinelloides has been analysed under various culturing conditions; effect of the elevation of their copy number on the carotenoid and ergosterol content as well as on the sensitivity to statins has also been examined.

Results
Transcripts of each gene were detected and their relative levels varied under the tested conditions. Transcripts of hmgR1 were detected only in the mycelium and its relative transcript level seems to be strongly controlled by the temperature and the oxygen level of the environment. Transcripts of hmgR2 and hmgR3 are already present in the germinating spores and the latter is also strongly regulated by oxygen. Overexpression of hmgR2 and hmgR3 by elevating their copy numbers increased the carotenoid content of the fungus and decreased their sensitivity to statins.

Conclusions
The three HMG-CoA reductase genes of M. circinelloides displayed different relative transcript levels under the tested conditions suggesting differences in their regulation. They seem to be especially involved in the adaptation to the changing oxygen tension and osmotic conditions of the environment as well as to statin treatment. Overexpression of hmgR2 and hmgR3 may be used to improve the carotenoid content.
A prediction model for renal artery stenosis using carotid ultrasonography measurements in patients undergoing coronary angiography
Authors: Lee Yonggu , Shin Jeong-Hun , Park Hwan-Cheol , Kim Soon Gil , Choi Seong-il 
Published: April 2014

Abstract

Background
Carotid intima-media thickness (CIMT) and carotid atherosclerotic plaque (CAP) are well-known indicators of atherosclerosis. However, few studies have reported the value of CIMT and CAP for predicting renal artery stenosis (RAS). We investigated the predictive value of CIMT and CAP for RAS and propose a model for predicting significant RAS in patients undergoing coronary angiography (CAG).

Methods
Consecutive patients who underwent renal angiography at the time of CAG in a single center in 2011 were included. RAS ≥50% was considered significant. Multiple logistic regression analysis with step-down variable selection method was used to select the best model for predicting significant RAS and bootstrap resampling was used to validate the best model. A scoring system for predicting significant RAS was developed by adding the closest integers proportional to the coefficients of the regression formula.

Results
Significant RAS was observed in 60 of 641 patients (9.6%) who underwent CAG. Hypertension, diabetes, significant coronary artery disease (CAD) and chronic kidney disease (CKD) stage ≥3 were more prevalent in patients with significant RAS. Mean age, CIMT and number of anti-hypertensive medications (AHM) were higher and body mass index (BMI) and total cholesterol level were lower in patients with significant RAS. Multiple logistic regression analysis identified significant CAD (odds ratio (OR) 5.6), unilateral CAP (OR 2.6), bilateral CAP (OR 4.9), CKD stage ≥3 (OR 4.8), four or more AHM (OR 4.8), CIMT (OR 2.3), age ≥67 years (OR 2.3) and BMI <22 kg/m2 (OR 2.4) as independent predictors of significant RAS. The scoring system for predicting significant RAS, which included these predictors, had a sensitivity of 83.3% and specificity of 81.6%. The predicted frequency of the scoring system agreed well with the observed frequency of significant RAS (coefficient of determination r
2 = 0.957).

Conclusions
CIMT and CAP are independent predictors of significant RAS. The proposed scoring system, which includes CIMT and CAP, may be useful for predicting significant RAS in patients undergoing CAG.
Multiple-level power allocation strategy for secondary users in cognitive radio networks
Authors: Chen Zhong , Gao Feifei , Zhang Zhengwei , Li James CF , Lei Ming 
Published: April 2014

Abstract
In this paper, we propose a new multiple-level power allocation strategy for the secondary user (SU) in cognitive radio (CR) networks. Different from the conventional strategies, where SU either stays silent or transmit with a constant/binary power depending on the busy/idle status of the primary user (PU), the proposed strategy allows SU to choose different power levels according to a carefully designed function of the receiving energy. The way of the power level selection at SU side is optimized to maximize the achievable rate of SU under the constraints of average transmit power at SU and average interference temperature to PU. Simulation results demonstrate that the proposed strategy can significantly improve the throughput of SU compared to the conventional strategies.
Retraining function in people with Parkinson’s disease using the Microsoft kinect: game design and pilot testing
Authors: Galna Brook , Jackson Dan , Schofield Guy , McNaney Roisin , Webster Mary , Barry Gillian , Mhiripiri Dadirayi , Balaam Madeline , Olivier Patrick , Rochester Lynn 
Published: April 2014

Abstract

Background
Computer based gaming systems, such as the Microsoft Kinect (Kinect), can facilitate complex task practice, enhance sensory feedback and action observation in novel, relevant and motivating modes of exercise which can be difficult to achieve with standard physiotherapy for people with Parkinson’s disease (PD). However, there is a current need for safe, feasible and effective exercise games that are appropriate for PD rehabilitation. The aims of this study were to i) develop a computer game to rehabilitate dynamic postural control for people with PD using the Kinect; and ii) pilot test the game’s safety and feasibility in a group of people with PD.

Methods
A rehabilitation game aimed at training dynamic postural control was developed through an iterative process with input from a design workshop of people with PD. The game trains dynamic postural control through multi-directional reaching and stepping tasks, with increasing complexity across 12 levels of difficulty. Nine people with PD pilot tested the game for one session. Participant feedback to identify issues relating to safety and feasibility were collected using semi-structured interviews.

Results
Participants reported that they felt safe whilst playing the game. In addition, there were no adverse events whilst playing. In general, the participants stated that they enjoyed the game and seven of the nine participants said they could imagine themselves using the game at home, especially if they felt it would improve their balance. The Flow State Scale indicated participants were immersed in the gameplay and enjoyed the experience. However, some participants reported that they found it difficult to discriminate between different types and orientations of visual objects in the game and some also had difficulty with the stepping tasks, especially when performed at the same time as the reaching tasks.

Conclusion
Computer-based rehabilitation games using the Kinect are safe and feasible for people with PD although intervention trials are needed to test their safety, feasibility and efficacy in the home.
Age at onset determines severity and choice of treatment in early rheumatoid arthritis: a prospective study
Authors: Innala Lena , Berglin Ewa , Möller Bozena , Ljung Lotta , Smedby Torgny , Södergren Anna , Magnusson Staffan , Rantapää-Dahlqvist Solbritt , Wållberg-Jonsson Solveig 
Published: April 2014

Abstract
Introduction
Disease activity, severity and comorbidity contribute to increased mortality in patients with rheumatoid arthritis (RA). We evaluated the impact of age at disease onset on prognostic risk factors and treatment in patients with early disease.

Methods
In this study, 950 RA patients were followed regularly from the time of inclusion (<12 months from symptom onset) for disease activity (erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), tender and/or swollen joints, Visual Analogue Scale pain and global scores, and Disease Activity Score in 28 joints (DAS28)) and function (Health Assessment Questionnaire (HAQ)). Disease severity, measured on the basis of radiographs of the hands and feet (erosions based on Larsen score), extraarticular disease, nodules, and comorbidities and treatment (disease-modifying antirheumatic drugs (DMARDs), corticosteroids, biologics and nonsteroidal anti-inflammatory drugs) were recorded at the time of inclusion and at 5 years. Autoantibodies (rheumatoid factor, antinuclear antibodies and antibodies against cyclic citrullinated peptides (ACPAs)) and genetic markers (human leucocyte antibody (HLA) shared epitope and protein tyrosine phosphatase nonreceptor type 22 (PTPN22)) were analysed at the time of inclusion. Data were stratified as young-onset RA (YORA) and late-onset RA (LORA), which were defined as being below or above the median age at the time of onset of RA (58 years).

Results
LORA was associated with lower frequency of ACPA (P < 0.05) and carriage of PTPN22-T variant (P < 0.01), but with greater disease activity at the time of inclusion measured on the basis of ESR (P < 0.001), CRP (P < 0.01) and accumulated disease activity (area under the curve for DAS28 score) at 6 months (P < 0.01), 12 months (P < 0.01) and 24 months (P < 0.05), as well as a higher HAQ score (P < 0.01) compared with YORA patients. At baseline and 24 months, LORA was more often associated with erosions (P < 0.01 for both) and higher Larsen scores (P < 0.001 for both). LORA was more often treated with corticosteroids (P < 0.01) and less often with methotrexate (P < 0.001) and biologics (P < 0.001). YORA was more often associated with early DMARD treatment (P < 0.001). The results of multiple regression analyses supported our findings regarding the impact of age on chosen treatment.

Conclusion
YORA patients were more frequently ACPA-positive than LORA patients. LORA was more often associated with erosions, higher Larsen scores, higher disease activity and higher HAQ scores at baseline. Nevertheless, YORA was treated earlier with DMARDs, whilst LORA was more often treated with corticosteroids and less often with DMARDs in early-stage disease. These findings could have implications for the development of comorbidities.