bluuebunny/crossref_metadata_2025_split huggingface dataset:
Case Article–Forecasting at FoodMart: A Case on Cultural Diversity in Supply Chain Management
Authors: David Amy 
Published: August 2024

This case focuses on forecasting a number of grocery items from the perspective of a demand planner who notices that the items have irregular patterns in the seasonality of their historical sales. It introduces students to the need for diverse cultural knowledge in forecasting certain consumer products and provides instructors with a starting point for discussing the business case for diversity and the value of diverse teams in a supply chain management context. This case is recommended for use in an undergraduate-level course in supply chain management, operations management, or business analytics. Learning goals are for students to identify irregular patterns in historical sales data and determine their root causes, evaluate a statistical forecast created without human intervention, and explain how culturally diverse teams can be valuable in a forecasting process. Supplemental Material: The Teaching Note and grocery forecasting Excel spreadsheet are available at https://www.informs.org/Publications/Subscribe/Access-Restricted-Materials .
Mycophenolate mofetil for the treatment of warm autoimmune haemolytic anaemia post-rituximab therapy: a case series
Authors: Borja-Montes Oscar F. , Toro-Pedroza Alejandro , Horton Darrell D. , Andritsos Leslie A. , Ebaid Ala 
Published: August 2024

Background: Warm autoimmune haemolytic anaemia (wAIHA) is an acquired haemolytic disorder most commonly treated with a combination of corticosteroids, rituximab and/or splenectomy. Third-line therapies for refractory cases include immunosuppressive agents. Mycophenolate mofetil is frequently used in these scenarios, although its use is supported by small studies and anecdotal evidence rather than large-scale data. Case description: We describe three cases of refractory warm autoimmune haemolytic anaemia successfully treated with mycophenolate mofetil. Case 1: A persistent case of autoimmune haemolytic anaemia in a 56-year-old was ultimately managed with mycophenolate mofetil, leading to successful steroid tapering and stable haemoglobin levels without relapse. Case 2: A woman with a complex oncological history, including lymphoma and breast cancer, achieved remission with mycophenolate therapy, maintaining stability post-steroid treatment. Case 3: Mycophenolate proved effective for a 63-year-old with cirrhosis after recurrent autoimmune anaemia and deep vein thrombosis, enabling cessation of steroids and maintaining remission. Conclusion: Management of this condition can be challenging and balancing the available treatments is crucial to reduce potential complications from long-term therapies that appear to be ineffective. Our case series demonstrates anecdotal experience on successful use of mycophenolate mofetil for complex refractory cases of wAIHA.
Comparison of metrics for assessing face washing behaviour for trachoma control
Authors: Greenland Katie , Collin Claire , Sinba Etu Edao , Guye Meseret , Hika Demitu , Macleod David , Schmidt Wolf-Peter , Shafi Abdurahman Oumer , Last Anna , Burton Matthew J. 
Published: August 2024

There is currently no single, easy-to-use, reliable indicator to assess whether a face has been washed with soap in the context of trachoma elimination. This study aimed to compare survey report, script-based pictorial recall and facial cleanliness indicators as alternatives to structured observation for measuring face washing behaviour. This method validation study was nested in the Stronger-SAFE trial, Oromia Region, Ethiopia. Structured observation was conducted in randomly selected households for three hours from dawn. The primary caregiver in each household participated in a survey to capture (self)-reported behaviour and/or script-based pictorial recall, a routine-based diary activity to covertly capture information on face washing behaviour of themself and any children aged 1–12. Children 4–12 years old directly participated in the survey and pictorial recall in a subset of households. The facial cleanliness of children aged 1–12 was assessed qualitatively and using the quantitative Personal Hygiene Assessment Tool (qPHAT). Prevalence estimates, sensitivity, specificity and predictive values were computed for each behavioural indicator with observation data as the gold standard. The appropriateness of script-based pictorial recall was assessed using baseline and 3-month follow-up data. Baseline data were collected from 204 households in 68 clusters. Survey estimates of face washing and face washing with soap among caregivers and children were 32% to 60% and 5% to 31% higher than observed behaviour, respectively. Face washing prevalence estimates from pictorial recall were lower than survey estimates and comparable with observations for some face washing with soap indicators (0.3% to 13% higher than observations). Specificity of pictorial recall indicators was high (85% to 99%), but the sensitivity was low (0% to 67%), resulting in a low positive predictive value for all indicators. Both qualitative facial cleanliness indicators and qPHAT scores were poorly correlated with observed face washing earlier that morning. Pictorial recall overestimated face washing with soap among both caregivers and children following intervention delivery but not at baseline. Survey (self)-reported data on face washing is highly inaccurate. Script-based pictorial recall does not correctly classify those who wash their face with soap, and is subject to differential bias following intervention exposure, and facial cleanliness is a poor indicator of recent face washing in settings where faces become rapidly dirty again after washing. Alternatives to structured observation cannot be recommended to monitor the effectiveness of face washing interventions in community settings.
Trial Registration ISRCTN registry ISRCTN40760473, https://doi.org/10.1186/ISRCTN40760473.
Ginseng Radix et Rhizoma enhanced the effect of metoprolol in chronic heart failure by inhibiting autophagy in male C57BL/6J mice
Authors: Zi-chang Niu , Xiao-ling Han , Qi Jin , Ting Liu , Ming-hui Ouyang , Hao-ping Mao 
Published: August 2024

BackgroundGinseng Radix et Rhizoma(GS) is frequently used as an adjuvant therapy for patients with heart failure (HF). Metoprolol is widely used in patients with HF. However, there is no report on the combined effects of GS and metoprolol in patients with HF.ObjectiveThis study investigated the combined effects of GS and metoprolol in male C57BL/6J mice with HF and the underlying mechanisms.Materials and methodsWe utilized a mouse myocardial HF model to measure the serum levels of creatine kinase (CK) and creatine kinase-MB form (CK-MB) using an automated biochemical analyzer. Lactate dehydrogenase (LDH) and cardiac troponin (cTnT) levels were determined using enzyme-linked immunosorbent assays. Autophagy of myocardial cells was evaluated using transmission electron microscopy, and changes in signal pathway proteins related to autophagy were analyzed by Western blotting.ResultsGS combined with metoprolol improved heart function, reduced heart damage, and decreased serum levels of CK, CK-MB, LDH, and cTnT. The combination of GS and metoprolol decreased autophagy in myocardial cells by reducing the levels of autophagy-related proteins (LC3, p62, Beclin1, and Atg5) and increasing the ratios of p-PI3K/PI3K, p-Akt/Akt, and p-mTOR/mTOR.ConclusionGS enhanced the anti-heart failure effect of metoprolol. Its mechanism of action might be related to the inhibition of autophagy mediated by the activation of the PI3K/Akt/mTOR pathway.
Transition of mild cognitive impairment to Alzheimer’s disease: Medications as modifiable risk factors
Authors: Wang Ying , Li Mingfei , Haughton Dominique , Kazis Lewis E. 
Published: August 2024

Background
Mild cognitive impairment (MCI) is a pre-clinical stage of Alzheimer’s disease (AD). Understanding the transition probabilities across the disease continuum of AD, ranging from MCI to AD to Mortality is crucial for the economic modeling of AD and effective planning of future interventions and healthcare resource allocation decisions. This study uses the Multi-state Markov model to quantify the transition probabilities along the disease progression and specifically investigates medications as modifiable risk factors of AD associated with accelerated or decelerated transition times from MCI to AD, MCI to mortality, and AD to mortality.

Methods
Individuals with MCI were identified from the National Alzheimer’s Coordinating Center between September 2005 and May 2021. A three-state Markov model was postulated to model the disease progression among three states: MCI, AD, and mortality with adjustment for demographics, genetic characteristics, comorbidities and medications. Transition probabilities, the total length of stay in each state, and the hazard ratios of the use of medications for diabetes, hypertension, and hypercholesterolemia (the known modifiable risk factors of AD) were evaluated for these transitions.

Results
3,324 individuals with MCI were identified. The probability of developing AD after one year since the initial diagnosis of MCI is 14.9%. After approximately 6 years from the initial diagnosis of MCI, the probability of transitioning to AD increases to nearly 41.7% before experiencing a subsequent decline. The expected total lengths of stay were 5.38 (95% CI: 0.002–6.03) years at MCI state and 7.61 (95%CI: 0.002–8.88) years at AD state. Patients with active use of lipid-lowering agents were associated with significantly lower hazards of transitioning from MCI to AD (HR: 0.83, 95%CI:0.71–0.96), MCI to mortality (HR: 0.51, 95%CI:0.34–0.77), and AD to mortality (HR: 0.81, 95%CI:0.66–0.99).

Conclusions
Results suggest that lipid-lowering agents may confer a protective effect, delaying the onset of AD. Additionally, lipid-lowering agents indicate a favorable association with a longer survival time.
Longitudinal evidence of the influence of early life circumstances, family characteristics, social ties and psychological distress on healthy behaviours of Brazilian adults: The Pro-Saude cohort study
Authors: Vettore Mario V. , Stea Tonje H. , Zahl-Olsen Rune , Faerstein Eduardo 
Published: August 2024

Background
This study examined the influence of early life circumstances, family characteristics, social ties and psychological distress in adulthood on adult’s health-related behaviours.

Methods
A cohort study (Pro-Saúde Study) involving technical and administrative civil servants at university campuses in Rio de Janeiro State, Brazil was conducted in Rio de Janeiro, Brazil. Data from 2155 adults were collected at baseline (1999) and after a 13-year period (2012–13). Family characteristics at 12 years of age were assessed retrospectively in 1999. Gender, marital status, living situation, social support, social networks of relatives and psychological distress were also measured in 1999. Data collection in 2012–13 included information about marital status, social networks of relatives, cigarette smoking, fruit and vegetable consumption and physical exercise. A conceptual model testing the relationships between variables was assessed through structural equation modelling.

Results
Female gender (β = 0.043), better social networks of relatives in 1999 (β = 0.053) and 2012–13 (β = 0.069) and low psychological distress (β = -0.048) directly predicted less smoking. Better social networks of relatives in 2012–13 was directly linked to higher consumption of fruits (β = 0.045) and vegetables (β = 0.051) and being physically active (β = 0.070). Low psychological distress directly predicted higher fruit consumption (β = -0.040). Family characteristics at 12 years-old, marital status and living with other people were linked indirectly with health behaviours through social networks, social support and psychological distress.

Conclusions
Adults with better early life family and social circumstances, and those who were married reported positive health behaviours through indirect pathways. Stronger social ties and lower psychological distress represented the pathways by which early life circumstances and relationship status influenced positive health behaviours.
Short-term multicomponent exercise training improves executive function in postmenopausal women
Authors: Ramadhana Dani Rahmat , Putra Rizki Prayuda , Sibarani Michelle Abigail , Sulistiawati Sulistiawati , Sari Dewi Ratna , Rejeki Purwo Sri , Herawati Lilik , Argarini Raden 
Published: August 2024

Declined cognitive function is commonly complained during the menopausal transition and continues afterward. Combining different exercises potentially leads to greater improvements in cognitive function, however, evidence of the benefits that accrue with multicomponent exercise training, specifically for postmenopausal women is limited. Therefore, this study aimed to investigate the effects of short-term multicomponent exercise training programs on executive function in postmenopausal women. Thirty women (59.8 ± 5.2 years), who were at least 12 months post menopause were allocated into a control (CON) group and an exercise (EX) training group. The EX group underwent a 2-week (five times/week) multicomponent exercise program comprising aerobic, strength, flexibility, and balance exercises for 40–60 min. Executive function was assessed by using the Stroop test and global cognitive function was assessed using the Mini-Mental State Examination (MMSE) at baseline (pre) and after 2 weeks (post) of exercise. The EX group showed improved performance in the Stroop test, with faster inhibition reaction time (ES (g) = 0.76; p = 0.039) and fewer errors across all tasks (color naming: g = 0.8, p = 0.032; word reading: g = 0.88, p = 0.019; inhibition: g = 0.99, p = 0.009; switching: g = 0.93, p = 0.012) following exercise intervention. Additionally, statistical analysis of the MMSE score showed a significant improvement (g = 1.27; p = 0.001). In conclusion, our findings suggest that a short-term multicomponent exercise program improves selective tasks of executive function in postmenopausal women along with global cognitive function.
Trial registration
ISRCTN13086152
The effects of drone transportation on routine laboratory, immunohematology, flow cytometry and molecular analyses
Authors: Weekx Steven , Van Lint Philippe , Jacobs Sam 
Published: August 2024

Abstract

Objectives
Transportation of medical samples between laboratories or hospital sites is typically performed by motorized ground transport. Due to the increased traffic congestions in urban environments, drone transportation has become an attractive alternative for fast shipping of samples. In accordance with the CLSI guidelines and the ISO 15189 standard, the impact of this transportation type on sample integrity and performance of laboratory tests must be thoroughly validated.

Methods
Blood samples from 36 healthy volunteers and bacterial spiked urine samples were subjected to a 20–40 min drone flight before they were analyzed and compared with their counterparts that stayed on the ground. Effects on stability of 30 routine biochemical and hematological parameters, immunohematology tests and flow cytometry and molecular tests were evaluated.

Results
No clinically relevant effects on blood group typing, flow cytometry lymphocyte subset testing and on the stability of the multicopy opacity-associated proteins (Opa) genes in bacterial DNA nor on the number of Abelson murine leukemia viral oncogene homolog 1 (abl) housekeeping genes in human peripheral blood cells were seen. For three of the 30 biochemistry and hematology parameters a statistically significant difference was found: gamma-glutamyl transferase (gamma-GT), mean corpuscular hemoglobin (MCH) and thrombocyte count. A clinically relevant effect however was only seen for potassium and lactate dehydrogenase (LDH).

Conclusions
Multi-rotor drone transportation can be used for medical sample transportation with no effect on the majority of the tested parameters, including flow cytometry and molecular analyses, with the exception of a limited clinical impact on potassium and LDH.
On the energy decay of a coupled nonlinear suspension bridge problem with nonlinear feedback
Authors: Al-Gharabli Mohammad M. 
Published: August 2024

Abstract
In this article, we study a mathematical model for a one-dimensional suspension bridge problem with nonlinear damping. The model takes into consideration the vibration of the bridge deck in the vertical plane and main cable from which the bridge deck is suspended by the suspenders. We use the multiplier method to establish explicit and generalized decay results, without imposing restrictive growth assumption near the origin on the damping terms. Our results substantially improve, extend, and generalize some earlier related results in the literature.
On nonexistence ofD(n)-quadruples
Authors: Franušić Zrinka , Jurasić Ana 
Published: August 2024

AbstractIn this paper, we show that there is no polynomialD(n)-quadruple in ℤ[X] for some polynomialsn∈ ℤ[X] that are not representable as a difference of squares of two polynomials in ℤ[X].
Euclidean operator radius inequalities of d-tuple operators and operator matrices
Authors: Jana Suvendu , Bhunia Pintu , Paul Kallol 
Published: August 2024

Abstract
We study Euclidean operator radius inequalities of d-tuple operators as well as the sum and the product of d-tuple operators. A power inequality for the Euclidean operator radius of d-tuple operators is also studied. Further, we study the Euclidean operator radius inequalities of 2 × 2 operator matrices whose entries are d-tuple operators.
On certain star versions of the Hurewicz property using ideals
Authors: Chandra Debraj , Alam Nur 
Published: August 2024

Abstract
This article is a continuation of the study of star-𝓘-Hurewicz and strongly star-𝓘-Hurewicz properties done in [Das et al.:On certain variations of 𝓘-Hurewicz property, Topology Appl. 251 (2018), 363–376]. We primarily consider and study the relative versions of star-𝓘-Hurewicz and strongly star-𝓘-Hurewicz properties. We study their relationships with the star-Hurewicz, strongly star-Hurewicz, star-𝓘-Hurewicz, strongly star-𝓘-Hurewicz and similar other properties. Few related games are also studied.
Some animal protein antigens identified in cells of two plant species
Authors: Sahin İbrahim , Eroksuz Yesari , Ugur Kader , İncili Canan Akdeniz , Eroksuz Hatice , Aydin Gizem Nur , Ozpolat Emine , Bildirici Furkan , Aydin Suleyman 
Published: August 2024

Abstract

Objectives
It has been recently reported that immune activity of some animal peptides/proteins has been found in some plants. In this study, the presence of immune reactivity of alarin, asprosin, paraoxonase, elabela, glucagon, and nesfatin-1 like molecules was investigated in two plant species related to Kastamonu Taşköprü garlic (an endemic cultivar of the Allium sativum L.) and Tunceli garlic (Allium tuncelianum).

Methods
Ten Kastamonu and 10 Tunceli garlic were embedded in paraffin blocks and 4–5 μm transversal and longitudinal sections were taken and stained by immunohistochemical method. In addition, 500 mg of wet tissue samples were homogenized from these garlic and supernatants were obtained. The amounts of alarin, asprosin, elabela, glucagon and nesfatin-1 were studied by enzyme linked immunosorbent assay (ELISA) method and paraoxonase was studied by spectrophotometric method.

Results
Studied molecules show immune reactivity in the cytoplasm of the bulb storage cells of the plants parenchyma. The ELISA supernatant results also confirmed the presence of these animal molecules in the plants.

Conclusions
Although we cannot reveal the purpose of the presence of these animal molecules detected in plants with these existing data, we predict that these data will be a source of inspiration in the field of botany, that studies will shift in this direction and that they might contribute to the revision of the evolutionary processes of all living things, especially an ancestor of garlics.
Management and Clinical Outcomes of Neonatal Hypothermia in the Newborn Nursery
Authors: Dang Rebecca , Patel Anisha I. , Weng Yingjie , Schroeder Alan R. , Aby Janelle , Frymoyer Adam 
Published: August 2024

OBJECTIVES
Neonatal hypothermia has been shown to be commonly detected among late preterm and term infants. In preterm and very low birth weight infants, hypothermia is associated with increased morbidity and mortality. Little is known about the clinical interventions and outcomes in hypothermic late preterm and term infants. This study fills this gap in the evidence.

METHODS
Single-center retrospective cohort study using electronic health record data on infants ≥35 weeks’ gestation admitted to a newborn nursery from 2015 to 2021. Hypothermia was categorized by severity: none, mild (single episode, 36.0–36.4°C), and moderate or recurrent (&lt;36.0°C and/or 2+ episodes lasting at least 2 hours). Bivariable and multivariable logistic regression examined associations between hypothermia and interventions or outcomes. Stratified analyses by effect modifiers were conducted when appropriate.

RESULTS
Among 24 009 infants, 1111 had moderate or recurrent hypothermia. These hypothermic infants had higher odds of NICU transfer (adjusted odds ratio [aOR] 2.10, 95% confidence interval [CI] 1.68–2.60), sepsis evaluation (aOR 2.23, 95% CI 1.73–2.84), and antibiotic use (aOR 1.73, 95% CI 1.15–2.50) than infants without hypothermia. No infants with hypothermia had culture-positive sepsis, and receipt of antibiotics ≥72 hours (surrogate for culture-negative sepsis and/or higher severity of illness) was not more common in hypothermic infants. Hypothermic infants also had higher odds of blood glucose measurement and hypoglycemia, slightly higher percent weight loss, and longer lengths of stay.

CONCLUSIONS
Late preterm and term infants with hypothermia in the nursery have potentially unnecessary increased resource utilization. Evidence-based and value-driven approaches to hypothermia in this population are needed.
Diferente aroma, mismo color floral: el caso de dos especies de <i>Salvia</i> de corola blanca
Authors: Martínez-Díaz Yesenia , Ramírez Reyes Leopoldo , Bedolla-García Brenda , Cuevas Eduardo 
Published: August 2024

Background: Plants emit floral signals that are attractive to pollinators. Floral volatile organic compounds (VOCs) are considered a key signal in attracting pollinators. However, it has been scarcely explored whether flowers of the same color emit the same scent.
Questions: Do different species of Salvia with white corolla flowers emit the same floral scent and attract the same floral visitors?
Study species: Salvia assurgens and Salvia madrigalii, two species with white corolla but different floral morphology.
Study site: Temperate forest southeast of Morelia, Michoacán.
Methods: The floral scent was analyzed by gas/mass chromatography and floral visitor observations were carried out with video cameras.
Results: The chemical profile of floral scent (composition and relative quantity) differed between S. assurgens and S. madrigalii. In S. madrigalii we found 16 VOCs and it was visited exclusively by the hummingbird Amazilia beryllina, and in S. assurgens we found 11 VOCs and it was visited by four species of insects, being the butterfly Thorybes dorantes the most frequent visitor. Canonical correspondence analysis (CCA) showed that floral volatiles were significantly correlated with the visitation rate of floral visitors.
Conclusions: Our study shows evidence that Salvia species with white corolla flowers with different morphology emit different floral scents and attract particular floral visitors.