bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Highly Stereoselective Synthesis of Tertiary Propargylic Centers and Their Isomerization to Enantiomerically Enriched Allenes.
Authors: Garcia Ruano Jose Luis , Marzo Leyre , Marcos Vanesa , Alvarado Cuauhtemoc , Aleman Jose 
Published: January 2013

AbstractThe allenes are prepared by reaction of enantiomerically pure sulfinylated lithium benzylcarbanions with terminal arylsulfonylacetylenes followed by deprotonation of the resulting sulfinylphenyl propargylic derivatives with LDA at the benzylic position.
ChemInform Abstract: Oxidative Cyanation of Tertiary Amines with Ethyl Cyanoformate over a Niobia‐Supported Iron‐Exchanged Molybdophosphoric Acid Catalyst.
Authors: Rao Kasanneni Tirumala Venkateswara , Haribabu Bathula , Prasad Potharaju S. Sai , Lingaiah Nakka 
Published: January 2013

AbstractA simple, reusable (four times), and highly efficient heterogeneous catalyst is used for the title reaction under mild and environmentally friendly conditions.
ChemInform Abstract: A New Synthetic Route for 1,2‐Diketo Compounds Using Unexpected C—C Bond Cleavage by PCC.
Authors: Bhosale Shrikar M. , Momin Aadil A. , Gawade Rupesh L. , Piranik Vedavati G. , Kusurkar Radhika S. 
Published: January 2013

AbstractOxidative treatment of α‐hydroxy‐γ‐ketoesters with PCC results in efficient cleavage to give 1,2‐diones under mild conditions.
ChemInform Abstract: Direct Amidation of Alcohols with N‐Substituted Formamides under Transition‐Metal‐Free Conditions.
Authors: Xu Kun , Hu Yanbin , Zhang Sheng , Zha Zhenggen , Wang Zhiyong 
Published: January 2013

AbstractTertiary amides are derived from benzyl alcohols and formamides using tBuOOH as optimal oxidant in the presence of catalytic amounts of iodine and NaOH.
ChemInform Abstract: Oxidative Trifluoromethylthiolations of Aryl Boronic Acids Using a Copper O2‐Based Protocol.
Authors: Zhang Cheng‐Pan , Vicic David A. 
Published: January 2013

AbstractWith the absence of any known procedure to form aryl trifluoromethyl sulfides directly from aryl chlorides, the present method can be carried out simply in the presence of air without the use of silver oxidants.
ChemInform Abstract: Synthesis of Biaryl Derivatives via a Magnetic Pd‐NPs‐Catalyzed One‐Pot Diazotization—Cross‐Coupling Reaction.
Authors: Zong Yan , Hu Jiefeng , Sun Peipei , Jiang Xiaoqing 
Published: January 2013

AbstractThe one‐pot diazotization‐cross coupling reaction of anilines (I) and arylboronic acids (II) affords the biaryls (III) in sufficient to high yields [with exception of (IIId)].
ChemInform Abstract: Palladium‐Catalyzed Allylic Cross‐Coupling Reactions of Primary and Secondary Homoallylic Electrophiles.
Authors: Stokes Benjamin J. , Opra Susanne M. , Sigman Matthew S. 
Published: January 2013

AbstractA general, simple, and mild title reaction is developed for a broad scope of substrates by using an easily prepared and air stable precatalyst.
ChemInform Abstract: Synthesis of Polysubstituted Naphthalenes by Iron‐Catalyzed [2 + 2 + 2] Annulation of Grignard Reagents with Alkynes.
Authors: Ilies Laurean , Matsumoto Arimasa , Kobayashi Motoaki , Yoshikai Naohiko , Nakamura Eiichi 
Published: January 2013

AbstractThe iron‐catalyzed annulation reaction of internal alkynes with arylmagnesium compounds proceeds by C—H bond activation at low temperature under oxidative conditions to produce polysubstituted naphthalenes.
ChemInform Abstract: Pd‐Catalyzed Sequential C—C Bond Formation and Cleavage: Evidence for an Unexpected Generation of Arylpalladium(II) Species.
Authors: Youn So Won , Kim Byung Seok , Jagdale Arun R. 
Published: January 2013

AbstractA novel and concurrent preparation of 1‐naphthols through an uncovered unprecedented catalytic process is developed.
ChemInform Abstract: Enantioselective Synthesis of AG‐041R by Using N‐Heteroarenesulfonyl Cinchona Alkaloid Amides as Organocatalysts.
Authors: Hara Noriyuki , Nakamura Shuichi , Sano Masahide , Tamura Ryota , Funahashi Yasuhiro , Shibata Norio 
Published: January 2013

AbstractThe gastrin/cholecyctokinin‐B receptor antagonist AG‐041R is prepared based on an organocatalytic asymmetric addition of malonic acid half‐thioesters to isatin derivatives.
ChemInform Abstract: Catalytic and Enantioselective α‐Functionalization of Oxindoles Through Oxidative Reactions with Naphthoquinones.
Authors: Siau Woon‐Yew , Li Wenjun , Xue Fei , Ren Qiao , Wu Minghu , Sun Shaofa , Guo Haibing , Jiang Xuefeng , Wang Jian 
Published: January 2013

AbstractOptically active 3,3‐disubstituted oxindoles are obtained by a new organocatalyzed aerobic oxidative method.
ChemInform Abstract: Synthesis of Racemic and Chiral Carvedilol Starting from Corresponding 5‐(Chloromethyl)oxazolidin‐2‐one.
Authors: Kumar B. Anand , Babu K. Veera , Rao Rama Koteshwar , Srinivas Kumbam , Madhusudhan G. , Mukkanti K. 
Published: January 2013

AbstractAn improved synthesis of the non‐selective, β‐adrenergic receptor antagonist carvediol (VIII) which reduces significantly impurities, especially bis‐compounds, is developed.
ChemInform Abstract: One‐Pot Synthesis of Pyranocarbazoles by Ethylenediamine Diacetate Catalyzed Domino Aldol‐Type Reaction/6π‐Electrocyclization of Hydroxycarbazoles to α,β‐Unsaturated Aldehydes and Conversion into Other Pyranocarbazoles.
Authors: Pandit Rameshwar Prasad , Lee Yong Rok 
Published: January 2013

AbstractBiologically interesting title heterocycles are prepared under conditions A).
ChemInform Abstract: New Highly Soluble Dimedone‐Derived Iodonium Ylides: Preparation, X‐Ray Structure, and Reaction with Carbodiimide Leading to Oxazole Derivatives.
Authors: Zhu Chenjie , Yoshimura Akira , Solntsev Pavlo , Ji Lei , Wei Yunyang , Nemykin Victor N. , Zhdankin Viktor V. 
Published: January 2013

AbstractThe synthesis of new iodonium ylides derived from dimedone and bearing an ortho‐substituent in the phenyl ring is described.
ChemInform Abstract: Efficient and Green Approaches for the Synthesis of 4H‐Benzo[g]chromenes in Water, under Neat Conditions, and Using Task‐Specific Ionic Liquid.
Authors: Khurana Jitender M. , Magoo Devanshi , Chaudhary Ankita 
Published: January 2013

AbstractThe reaction of hydroxynaphthoquinone (I) with aromatic aldehydes and CH‐acids is studied under environmentally benign conditions.
ChemInform Abstract: Perchloric Acid‐Catalyzed Synthesis of 9‐Aryl Xanthenes‐9H‐3,6‐diol and 1,3,6,8‐Tetraol in Water.
Authors: Vidyasagar Nikhil , Nanda Rabindra , Mangal Rajesh , Kathiravan Muthu K. 
Published: January 2013

AbstractPerchloric acid can effectively catalyze the condensation reaction between phenols and aldehydes to afford functionalized xanthenes (III).
ChemInform Abstract: An Organocatalytic Cascade Approach Toward Polysubstituted Quinolines and Chiral 1,4‐Dihydroquinolines — Unanticipated Effect of N‐Protecting Groups.
Authors: Zhang Xinshuai , Song Xixi , Li Hao , Zhang Shilei , Chen Xiaobei , Yu Xinhong , Wang Wei 
Published: January 2013

AbstractThe outcome of the aza‐Michael/aldol cascade reaction of 2‐aminobenzaldehydes or the corresponding ketones with ynals depends on the choice of the N‐protecting group.
ChemInform Abstract: Water‐Solvent Method for the Synthesis of N‐Substituted and N‐,4‐Disubstituted 1,8‐Naphthalimides under Microwave Irradiation.
Authors: Zhang Ye , Feng Shao‐Bo , Wang Kai , Yi Xiang‐Hui , Wang Heng‐Shan , Pan Ying‐Ming 
Published: January 2013

AbstractTitle compounds of type (III) or (V) are prepared by microwave assisted recyclization with amines (II).
ChemInform Abstract: Ionic Liquid‐Catalyzed One‐Pot Synthesis of 1H‐Pyrano[2,3‐d]pyrimidin‐2(8aH)‐one Derivatives via Three‐Component Reaction under Solvent‐Free Conditions.
Authors: Guo Hong‐Yun , Li Xiao‐Jun , Yu Yi 
Published: January 2013

AbstractThe catalyst can be reused several times with only slight decrease in activity.
ChemInform Abstract: Studies on Retro‐[1,4] Brook Rearrangement of 3‐Silyl Allyloxysilanes. Observation of the Formation of Unusual 3,3‐Bissilyl Enols.
Authors: Gan Zubao , Wu Ya , Gao Lu , Sun Xianwei , Lei Jian , Song Zhenlei , Li Linjie 
Published: January 2013

AbstractRetro‐[1,4]‐Brook rearrangement of a wide variety of silyl allyloxysilanes is studied.
ChemInform Abstract: Efficient Conversion of N‐Terminal of L‐Tyrosine, DL‐Phenyl Alanine, and Glycine to Substituted 2‐Thioxo‐thiazolidine‐4‐ones: A Stereospecific Synthesis.
Authors: Kumar B. R. Prashantha , Basu Prabudha , Adhikary L. , Nanjan M. J. 
Published: January 2013

AbstractThe functionalization of the N‐terminus of various amino acids with a thioxothiazolidinone ring proceeds with retention of the configuration at the stereocenter.
ChemInform Abstract: 2,4,6‐Trichloro‐1,3,5‐triazine (TCT) Mediated One‐Pot Sequential Functionalization of Glycosides for the Generation of Orthogonally Protected Monosaccharide Building Blocks.
Authors: Tatina Madhubabu , Yousuf Syed Khalid , Mukherjee Debaraj 
Published: January 2013

AbstractThe advantages of the title reaction are a high regioselectivity, the use of a broad range of substrates and a mild, inexpensive, and nontoxic catalyst, functional‐group tolerance, mild reaction conditions, scalability (20 g), easy handling, and a wide application range.
ChemInform Abstract: Solvent‐Free Preparation of 5‐(α‐D‐Glucosyloxymethyl)furfural from Isomaltulose—Choline Chloride Melts.
Authors: Russ Carolin , Luff Claudia , Begli Alireza Haji , Koenig Burkhard 
Published: January 2013

AbstractThe title compound (II), a versatile building block from renewable resources, can be prepared in moderate yields from isomaltulose (I) in a choline chloride melt in the presence of acidic catalysts.
ChemInform Abstract: N‐Aryl Modification in γ‐Lactam: Design and Synthesis of Novel Monocyclic γ‐Lactam Derivatives as Inhibitor for Bacterial Propagation.
Authors: Patra Prasanta , Kar Gandhi K. , Sarkar Aparna , Ray Jayanta K. , Dasgupta Tista , Ghosh Mahua , Bhattacharya Sugata 
Published: January 2013

AbstractA series γ‐lactams of type (V), (VI), (VIII), (X), or (XI) are prepared.
ChemInform Abstract: Iron‐Containing Nanomaterials: Synthesis, Properties, and Environmental Applications
Authors: Kharisov Boris I. , Dias H. V. Rasika , Kharissova Oxana V. , Jimenez‐Perez Victor Manuel , Olvera Perez Betsabee , Munoz Flores Blanca 
Published: January 2013

AbstractReview: 322 refs.
A note from history: Landmarks in history of cancer, part 5
Authors: Hajdu Steven I. , Darvishian Farbod 
Published: January 2013

AbstractIn the 3 decades from 1910 to 1940, more progress took place in cancer research and the diagnosis and treatment of cancers than during the prior centuries combined. The discovery of several carcinogens, precancerous conditions, and hereditary cancers adduced new thoughts about the genesis of cancers. Even though diagnostic radiology and radiation therapy became apposite specialties, surgery retained its primacy in the treatment of cancer patients. The delineation of new and distinct neoplastic entities, several precancerous lesions, and noninvasive carcinomas as well as the introduction of histopathologic grading of cancers promulgated cogent changes in therapy. Yet, with all the advances in the diagnosis and treatment of cancers, very little betterment could be demonstrated in the overall survival of patients, and by the end of the 1930s, cancer became the second most common cause of death in the United States. Cancer 2013. © 2012 American Cancer Society.
Unique inhibitory cascade pattern of molars in canids contributing to their potential to evolutionary plasticity of diet
Authors: Asahara Masakazu 
Published: January 2013

AbstractDevelopmental origins that guide the evolution of dental morphology and dental formulae are fundamental subjects in mammalian evolution. In a previous study, a developmental model termed the inhibitory cascade model was established. This model could explain variations in relative molar sizes and loss of the lower third molars, which sometimes reflect diet, in murine rodents and other mammals. Here, I investigated the pattern of relative molar sizes (inhibitory cascade pattern) in canids, a taxon exhibiting a wide range of dietary habits. I found that interspecific variation in canid molars suggests a unique inhibitory cascade pattern that differs from that in murine rodents and other previously reported mammals, and that this variation reflects dietary habits. This unique variability in molars was also observed in individual variation in canid species. According to these observations, canid species have greater variability in the relative sizes of first molars (carnassials), which are functionally important for dietary adaptation in the Carnivora. In conclusion, an inhibitory cascade that differs from that in murine rodents and other mammals may have contributed to diverse dietary patterns and to their parallel evolution in canids.
Regioselective Double Organic Functionalization of Polyoxotungstates through Electrophilic Addition of Aromatic Isocyanates to [P2W17O61(SnR)]7–
Authors: Micoine Kévin , Malacria Max , Lacôte Emmanuel , Thorimbert Serge , Hasenknopf Bernold 
Published: January 2013

AbstractThe direct attachment of several different organic molecules to a single polyoxometalate remains a challenge in the field of functionalized polyoxometalates. In this paper, we show that an organotin‐functionalized Dawson‐type polyoxotungstate [P2W17O61(SnR)]7– reacts with aromatic isocyanates ArNCO to yield new doubly functionalized compounds [P2W17O61(SnR)(CONHAr)]6–. Both organic moieties, Ar and R, can be varied independently; we have tested nine Ar and three R groups. Therefore, this synthetic methodology represents a way to graft two distinct functional molecules directly onto a polyoxometalate.
Analysis of the Experimental Data for Pure and Diluted [FexZn1–x(bbtr)3](ClO4)2 Spin‐Crossover Solids in the Framework of a Mechanoelastic Model
Authors: Chakraborty Pradip , Enachescu Cristian , Hauser Andreas 
Published: January 2013

AbstractThe mechanoelastic model is applied to reproduce the experimental relaxation and thermal transition curves as determined for crystals of pure and diluted {[FexZn1–x(bbtr)3](ClO4)2}∞ [bbtr = 1,4‐di(1,2,3‐triazol‐1‐yl)butane] spin‐crossover systems. In the mechanoelastic model, the spin‐crossover complexes are situated in a hexagonal planar lattice, which is similar to the 2D coordination polymer with (3,6) network topology of [Fe(bbtr)3](ClO4)2. These complexes are linked by springs, which simulate the elastic interactions between them. Owing to the change in volume of the complexes during the spin transition, an elastic force accompanies the switch of every complex. This force propagates through the entire lattice and causes a shift of all molecules in the system and thus results in a new nuclear configuration. First, the ability of the model to reproduce various shapes of thermal transition and relaxation curves in pure compounds is analyzed; these range from gradual to very steep and include hysteresis behavior for the former and from single exponential to sigmoidal or with several steps for the latter. A structural phase transition can also be accounted for by changing the shape of the sample at a fixed temperature from a regular to an elongated hexagon. Furthermore, the effect of adding Zn as a dopant in a mixed crystal series is discussed. The role of dopants on the cluster evolution is also analyzed directly and by using the correlation factor.
Stereoselective Synthesis of Tetrahydroquinolines Through an Imino‐Ene Cyclization Reaction
Authors: Bondalapati Somasekhar , Indukuri Kiran , Ghosh Priya , Saikia Anil K. 
Published: January 2013

AbstractTetrahydroquinolines have been efficiently synthesized in good yields with excellent stereoselectivity. The reaction between α‐allylic anilines and aldehydes proceeds through an imino‐ene cyclization that is mediated by boron trifluoride–diethyl ether.
Sodium‐dependent transport of ascorbic acid in U937 cell mitochondria
Authors: Azzolini Catia , Fiorani Mara , Cerioni Liana , Guidarelli Andrea , Cantoni Orazio 
Published: January 2013

AbstractU937 cells exposed to physiological concentrations of ascorbic acid (AA) accumulate the reduced form of the vitamin in the cytosol and even further in their mitochondria. In both circumstances, uptake was dependent on Na+‐AA‐cotransport, with hardly any contribution of hexose transporters, which might be recruited to transport the oxidized form of the vitamin. There was an identical linear relationship between the mitochondrial accumulation of the vitamin and the extramitochondrial AA concentration, regardless of whether detected in experiments using intact cells or isolated mitochondria. Western blot experiments revealed expression of both SVCT1 and 2 in plasma membranes, whereas SVCT2 was the only form of the transporter expressed at appreciable amounts in mitochondria. These results therefore provide the novel demonstration of SVCT2‐dependent mitochondrial transport of AA and hence challenge the present view that mitochondria only take up the oxidized form of the vitamin. © 2013 IUBMB Life, 65(2)149–153, 2013
Calculation of wave‐functions with frozen orbitals in mixed quantum mechanics/molecular mechanics methods. II. Application of the local basis equation
Authors: Ferenczy György G. 
Published: January 2013

AbstractThe application of the local basis equation (Ferenczy and Adams, J. Chem. Phys. 2009, 130, 134108) in mixed quantum mechanics/molecular mechanics (QM/MM) and quantum mechanics/quantum mechanics (QM/QM) methods is investigated. This equation is suitable to derive local basis nonorthogonal orbitals that minimize the energy of the system and it exhibits good convergence properties in a self‐consistent field solution. These features make the equation appropriate to be used in mixed QM/MM and QM/QM methods to optimize orbitals in the field of frozen localized orbitals connecting the subsystems. Calculations performed for several properties in divers systems show that the method is robust with various choices of the frozen orbitals and frontier atom properties. With appropriate basis set assignment, it gives results equivalent with those of a related approach [G. G. Ferenczy previous paper in this issue] using the Huzinaga equation. Thus, the local basis equation can be used in mixed QM/MM methods with small size quantum subsystems to calculate properties in good agreement with reference Hartree–Fock–Roothaan results. It is shown that bond charges are not necessary when the local basis equation is applied, although they are required for the self‐consistent field solution of the Huzinaga equation based method. Conversely, the deformation of the wave‐function near to the boundary is observed without bond charges and this has a significant effect on deprotonation energies but a less pronounced effect when the total charge of the system is conserved. The local basis equation can also be used to define a two layer quantum system with nonorthogonal localized orbitals surrounding the central delocalized quantum subsystem. © 2013 Wiley Periodicals, Inc.
Synthesis of Tungsten Oxide Nanorods by the Controlling Precipitation Reaction: Application for Hydrogen Evolution Reaction on a WO3 Nanorods/Carbon Nanotubes Composite Film Modified Electrode
Authors: Chekin Fereshteh , Bagheri Samira , Bee Abd Hamid Sharifah 
Published: January 2013

AbstractTungsten trioxide nanorods (WO3) were prepared by controlling the precipitation reaction of sodium tungstate dehydrates solution and hydrothermal process. The synthesized tungsten trioxide nanorods have been characterized by X‐ray diffraction (XRD), energy dispersive spectroscopy (EDS), scanning electron microscopy (SEM), cyclic voltammetry (CV) and linear sweep voltammetry (LSV). Electrochemical activity for hydrogen evolution reaction (HER) on WO3 nanorods / carbon nanotube (WO3/CNT) composite electrocatalyst was first studied in acid solution (0.1 M H2SO4) at room temperature. The overall experimental results revealed that the electrocatalytic activity for HER on WO3/CNT is two order magnitude higher than those obtained with WO3 nanorods and is four times than in the case of commercial WO3 in 0.1 M H2SO4. On the other hand, the kinetic reaction mechanisms were discussed on WO3/CNT electrocatalysts in acid solution for HER. However, the rate‐determining step carries through Tafel reaction on commercial WO3, CNT, WO3 nanorods and WO3/CNT electrocatalysts in acidic solution was introduced.
Decomposition of Sparse Graphs into Forests and a Graph with Bounded Degree
Authors: Kim Seog‐Jin , Kostochka Alexandr V. , West Douglas B. , Wu Hehui , Zhu Xuding 
Published: January 2013

AbstractFor a loopless multigraph G, the fractional arboricity Arb(G) is the maximum of over all subgraphs H with at least two vertices. Generalizing the Nash‐Williams Arboricity Theorem, the Nine Dragon Tree Conjecture asserts that if , then G decomposes into forests with one having maximum degree at most d. The conjecture was previously proved for ; we prove it for and when and . For , we can further restrict one forest to have at most two edges in each component.For general , we prove weaker conclusions. If , then implies that G decomposes into k forests plus a multigraph (not necessarily a forest) with maximum degree at most d. If , then implies that G decomposes into forests, one having maximum degree at most d. Our results generalize earlier results about decomposition of sparse planar graphs.
Hospitalist Staffing and Patient Satisfaction in the National Medicare Population
Authors: Chen Lena M. , Birkmeyer John D. , Saint Sanjay , Jha Ashish K. 
Published: January 2013

BACKGROUNDPayers are increasingly holding hospitals accountable for patients' experiences with their care. This may conflict with another trend among US hospitals—greater hospitalist care—as hospitalists may have less familiarity with the history and preferences of their patients compared with primary‐care physicians.OBJECTIVEOur objective was to better understand the relationship between hospitalist care and patients' experiences with their care.DESIGNThis was a retrospective cohort study.SETTINGThe setting was 2843 US acute‐care hospitals (bottom tertile or “non‐hospitalist” hospitals: median of 0% of general‐medicine patients cared for by hospitalists; middle tertile or “mixed” hospitals: median of 39.5%; top tertile or “hospitalist” hospitals: median of 76.5%).PATIENTSThe patients were 132,814 hospitalized Medicare beneficiaries cared for by a general medicine physician in 2009.MEASUREMENTSThe measurements were hospitalist use, based on Medicare claims data, and patient satisfaction, as measured by the Hospital Consumer Assessment of Healthcare Providers and Systems survey.RESULTS“Hospitalist” hospitals had better performance on global measures of patient satisfaction than “mixed” or “non‐hospitalist” hospitals (overall satisfaction: 65.6% vs 63.9% vs 63.9%, respectively, P value for difference < 0.001). Hospitalist hospitals performed better in 6 specific domains of care, with the largest difference in satisfaction with discharge compared with mixed or non‐hospitalist hospitals (80.3% vs 79.1% vs 78.1%, P < 0.001). Hospitalist care was not associated with patient satisfaction in 2 domains of care: cleanliness of room and communication with physician.CONCLUSIONFor most measures of patient satisfaction, greater hospitalist care was associated with modestly better patient‐centered care. Journal of Hospital Medicine 2013;8:126–131. © 2012 Society of Hospital Medicine