bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Simple and Efficient Synthesis of Trisubstituted Imidazoles.
Authors: Kolos N. N. , Chechina N. V. , Zamigailo L. L. , Vashchenko E. V. 
Published: March 2014

AbstractTitle compounds containing a 1,3‐dimethylbarbituric acid residue are synthesized through one‐pot three‐component condensation of barbituric acid (I), glyoxal hydrates (II), and guanidine (III) or isothiuronium (V) salts under microwave conditions or with imidazoles (VII) under conventional heating.
ChemInform Abstract: Design, Synthesis and Biological Evaluation of Novel Mansonone E Derivatives Prepared via CuAAC Click Chemistry as Topoisomerase II Inhibitors.
Authors: Huang Shi‐Liang , et al. et al. 
Published: March 2014

Abstract28 Title compounds of type (V) are prepared by using the copper‐catalyzed azide‐alkyne cycloaddition click reaction as the key step.
ChemInform Abstract: Pyranoxanthones: Synthesis, Growth Inhibitory Activity on Human Tumor Cell Lines and Determination of Their Lipophilicity in Two Membrane Models.
Authors: Afonso Carlos M. M. , et al. et al. 
Published: March 2014

AbstractFourteen new pyranoxanthones, including three angular pyranoxanthone types (I), (II), and (III) are synthesized and evaluated for their cell growth inhibitory activity in four human tumor cell lines.
ChemInform Abstract: Cyclocondensation of 3(5)‐Aminopyrazoles with Arylglyoxals and Cyclohexane‐1,3‐diones.
Authors: Petrova O. N. , Zamigailo L. L. , Shirobokova M. G. , Shishkina S. V. , Shishkin O. V. , Musatov V. I. , Lipson V. V. 
Published: March 2014

AbstractThe title three‐component cyclocondensation reactions lead regioselectivity to partly hydrogenated 4‐aroyl‐substituted pyrazolo[3,4‐b]quinolin‐5‐ones or 5‐aroyl‐substituted pyrazolo[1,5‐a]quinazolin‐6‐ones.
ChemInform Abstract: RhIII‐Catalyzed C—H Activation: A Versatile Route Towards Various Polycyclic Pyridinium Salts.
Authors: Luo Ching‐Zong , Gandeepan Parthasarathy , Jayakumar Jayachandran , Parthasarathy Kanniyappan , Chang Yu‐Wei , Cheng Chien‐Hong 
Published: March 2014

AbstractA convenient, mild, and efficient method for the synthesis of a broad range of substituted isoquinolinium salts from pyridines and alkynes is presented.
ChemInform Abstract: Potassium Carbonate Mediated Unusual Transformation of 2,3‐Dihydroquinazolinone via Cascade Reaction.
Authors: Sharma Moni , Mahar Rohit , Shukla Sanjeev K. , Kant Ruchir , Chauhan Prem M. S. 
Published: March 2014

AbstractAn unusual highly regioselective cascade process is discovered resulting in the conversion of 3‐(2‐bromophenyl)‐2‐isopropyl‐2,3‐dihydroquinazolin‐4(1H)‐one to a series of 3‐substituted derivatives under mild reaction conditions.
ChemInform Abstract: A New Synthesis of Pyrido[4,3‐d]pyrimidin‐2‐ones.
Authors: Fesenko A. A. , Shutalev A. D. 
Published: March 2014

AbstractTitle compounds [(V) and (VIII)] are synthesized using the Staudinger—aza—Wittig reaction of dihydropyrimidinone derivatives (IV) or (VII), respectively.
ChemInform Abstract: Amino‐ and Hydroxymethylation of Hydride Adducts of 2‐Hydroxy‐3,5‐dinitropyridine.
Authors: Ivanova E. V. , Fedyanin I. V. , Surova I. I. , Blokhin I. V. , Atroshchenko Yu. M. , Shahkeldyan I. V. 
Published: March 2014

AbstractThe Mannich condensation of the hydride adduct of 2‐hydroxy‐3,5‐dinitropyridine with formaldehyde and primary amines leads to 1,5‐dinitro‐3,3‐diazabicyclo[3.3.1]nonan‐one derivatives (IV) or (V), depending on the reaction temperature.
ChemInform Abstract: Reduction of 7‐R Derivatives of 7H‐Tris[1,2,5]oxadiazolo[3,4‐b:3′,4′‐d:3′′,4′′‐f]azepine 1‐Oxide with Furoxan Ring Opening. Preparation of 4‐R‐4H‐Bis[1,2,5]oxadiazolo[3,4‐b:3′,4′‐f]azepine‐8,9‐diamines.
Authors: Stepanov A. I. , Dashko D. V. , Astrat'ev A. A. 
Published: March 2014

AbstractPd‐catalyzed reduction of the title trisoxadiazoloazepine‐1‐oxides by hydrogen or hydrazine hydrate is accompanied by opening of one furoxan ring to furnish bisoxadiazoloazepine‐8,9‐diamines such as (IV).
ChemInform Abstract: Boron Functionalization of BODIPY by Various Alcohols and Phenols
Authors: Brizet Bertrand , Bernhard Claire , Volkova Yulia , Rousselin Yoann , Harvey Pierre D. , Goze Christine , Denat Franck 
Published: March 2014

Abstractpreparation and photophysical study of novel BODIPY derivatives (I) (10 examples)
ChemInform Abstract: Synthesis of a Phosphine Imide Bearing a Hydrosilane Moiety, and Its Water‐Driven Reduction to a Phosphine.
Authors: Kano Naokazu , Yanaizumi Kazuhide , Meng Xiangtai , Havare Nizam , Kawashima Takayuki 
Published: March 2014

AbstractThree novel phosphine imides (III) and (V) are synthesized by lithiation of imide (I) followed by treatment with corresponding chlorosilane.
ChemInform Abstract: Ligand‐Free CuI‐Catalyzed Selective C—N Coupling of Aliphatic Amino Group of α‐Amino Acid Amides with ortho‐Dihaloarenes.
Authors: Wang Yan , Tu Xingzhao , Lv Xirui , Zhou Lihong , Zeng Qingle 
Published: March 2014

AbstractThe reaction proceeds without obvious racemization.
ChemInform Abstract: Glycosides from the Aerial Parts of Patrinia villosa
Authors: Lee Joo Young , Kim Ju Sun , Kim Yeong Shik , Kang Sam Sik 
Published: March 2014

Abstractisolation and structure elucidation of two new flavonoid glycosides, patrivilosides 1 (Ia), 2 (Ib), patrinovalerosidate (II), and two new saponins, patrinovilosides A and B
ChemInform Abstract: β‐Type Glycosidic Bond Formation by Palladium‐Catalyzed Decarboxylative Allylation.
Authors: Xiang Shaohua , Lu Zhiqiang , He Jingxi , Hoang Kim Le Mai , Zeng Jing , Liu Xue‐Wei 
Published: March 2014

AbstractA broad range of aromatic and aliphatic O‐ and S‐glycosides is accessible from easily prepared protected glycals by employing the described procedure.
ChemInform Abstract: Diamondoids: Functionalization and Subsequent Applications of Perfectly Defined Molecular Cage Hydrocarbons
Authors: Gunawan Maria A. , Hierso Jean‐Cyrille , Poinsot Didier , Fokin Andrey A. , Fokina Natalie A. , Tkachenko Boryslav A. , Schreiner Peter R. 
Published: March 2014

AbstractReview: 104 refs.
An interleaved high step‐up DC‐DC converter with double boost paths
Authors: Chen Yie‐Tone , Lin Wei‐Cheng , Liang Ruey‐Hsun 
Published: March 2014

SummaryThis paper proposed a novel high step‐up converter with double boost paths. The circuit uses two switches and one double‐path voltage multiplier cell to own the double boost and interleaved effects simultaneously. The voltage gain ratio of the proposed DC‐DC converter can be three times the ratio of the conventional boost converter such that the voltage stress of the switch can be lower. The high step‐up performance is in accordance with only one double‐path voltage multiplier cell. Therefore, the number of diodes and capacitors in the proposed converter can be reduced. Furthermore, the interleaved property of the proposed circuit can reduce the losses in the rectifier diode and capacitor. The prototype circuit with 24‐V input voltage, 250‐V output voltage, and 150‐W output power is experimentally realized to verify the validity and effectiveness of the proposed converter. Copyright © 2014 John Wiley & Sons, Ltd.
HINTW, a W‐chromosome HINT gene in chick, is expressed ubiquitously and is a robust female cell marker applicable in intraspecific chimera studies
Authors: Nagai Hiroki , Sezaki Maiko , Bertocchini Federica , Fukuda Kimiko , Sheng Guojun 
Published: March 2014

AbstractGrafting and transplantation experiments in embryology require proper distinction between host and donor tissues. For the avian model this has traditionally been achieved by using two closely related species (e.g., chick and quail) followed by species‐specific antibody staining. Here, we show that an in situ hybridization probe against the HINTW gene is a robust and reliable marker for female‐derived chicken cells. At all pre‐circulation stages tested, all cells in female embryos, independently confirmed by PCR analysis, were strongly positive for HINTW, whereas all male embryos were negative. This probe is broadly applicable in intra‐specific chick/chick chimera studies, and as a proof of principle, we utilized this probe to detect female cells in three experimental settings: (1) to mark female donor cells in a node transplantation assay; (2) to distinguish female cells in male/female twins generated by the Cornish pasty culture; and (3) to detect female half of the embryo in artificially generated bilateral gynandromorphs. A rapid, PCR based pre‐screening step increases the efficiency of obtaining desired donor/host sex combination from 25% to 100%. For most avian chimera studies, this female‐specific in situ probe is a low cost alternative to the commonly used QCPN antibody and to ubiquitous‐GFP chicken strains which are not widely available to the research community. genesis 52:424–430, 2014. © 2014 Wiley Periodicals, Inc.
Facile Synthesis of a 20‐Membered Macrocyclic Magnesium Sulfide Complex
Authors: Leung Wing‐Por , Chan Yuk‐Chi , Mak Thomas C. W. 
Published: March 2014

AbstractDeprotonation of 2,3‐pyrazyl‐linked bis(thiophosphorano)methane {CH2(iPr2P=S)}2(C4H2N2‐2,3) (2) with one equivalent of nBu2Mg in THF afforded a 20‐membered macrocyclic magnesium complex [Mg{CH(iPr2P–S)}2(C4H2N2‐2,3)]4 (4a). The structure of 4a has been characterized by X‐ray crystallography and NMR spectroscopy.
Synthesis, Photophysical Properties, and Self‐Organization of Difurobenzosilole Derivatives
Authors: Li Liangchun , Li Shuhong , Zhao Cui‐Hua , Xu Caihong 
Published: March 2014

AbstractA facile synthetic route was developed to fuse furan rings to a dibenzosilole core for the construction of difurobenzosilole derivatives through an electrophilic double cyclization reaction. Only silafluorene derivatives with electron‐donating groups on the periphery participated in this cyclization. Suzuki–Miyaura coupling and deiodination of the diiododifurobenzosiloles resulted in highly emissive silicon‐bridged dibenzofuran compounds. These obtained compounds exhibited very high luminescent quantum yields (93 to about 99 %) and good thermal stability. Single crystals of the silicon‐bridged dibenzofuran compound with a marginal phenyl group were easily grown and analyzed by single‐crystal X‐ray diffraction, whereas the deiodinated silicon‐bridged dibenzofuran compound showed a high tendency to self‐organize into 1D microfibers in various solvents such as hexane, toluene, and THF.
Pressure‐Induced Metallic Conductivity in the Single‐Component Molecular Crystal [Ni(dmit)2]
Authors: Cui Hengbo , Tsumuraya Takao , Miyazaki Tsuyoshi , Okano Yoshinori , Kato Reizo 
Published: March 2014

AbstractGiven that a molecular system has a soft lattice, high‐pressure applications are effective ways to discover new single‐component molecular metals and superconductors. In this study, we measured the high‐pressure electrical resistivity of a single‐component molecule crystal of [Ni(dmit)2] (dmit = 1,3‐dithiole‐2‐thione‐4,5‐dithiolate) up to 25.5 GPa by using a newly developed diamond anvil cell technique that generates high‐quality hydrostatic pressures. We successfully observed the metallic state over a wide temperature range above 15.9 GPa. Two different band calculation methods, tight‐binding calculations coupled with the interatomic repulsion model and ab initio DFT calculations, indicated that 2D and 3D Fermi surfaces appear under high pressures.
Synthesis, Characterisation, and Organocatalytic Activity of Chiral Tetrathiahelicene Diphosphine Oxides
Authors: Cauteruccio Silvia , Dova Davide , Benaglia Maurizio , Genoni Andrea , Orlandi Manuel , Licandro Emanuela 
Published: March 2014

AbstractTwo new chiral tetrathia[7]helicene (7‐TH) based tertiary phosphine oxides (±)‐2b and (±)‐2c, bearing two substituents on the phosphorus atoms with different steric and electronic properties, have been synthesised and fully characterised by means of analytical and spectroscopic techniques. The resolution of (±)‐2a–c into their antipodes was accomplished by HPLC separation on a chiral stationary phase, and their chiroptical properties were investigated by CD spectroscopy. The behaviour of 2a–c as organocatalysts was assessed in representative reactions mediated by tri‐ or tetrachlorosilane. 7‐TH‐based phosphine oxides 2a and 2b promoted both ketoimine reduction and stereoselective carbon–carbon bond formation in good chemical yields and diastereoselectivity, albeit with low enantioselectivity, thus opening the way to the development of a novel class of enantiopure helical‐based phosphorus organocatalysts.
Enhancing the bioactivity of polymeric implants by means of cold gas spray coatings
Authors: Gardon M. , Melero H. , Garcia‐Giralt N. , Dosta S. , Cano I. G. , Guilemany J. M. 
Published: March 2014

AbstractNanostructured anatase coatings were built‐up on biocompatible polyetheretherketone (PEEK) by means of cold gas spray (CGS). Titanium layer was previously desposited, which acted as bond coat between PEEK and metal oxide. Semicrystalline polymer was not degraded during the spraying process and starting composition of titanium dioxide was not affected. TiO2 was homogeneously obtained onto CGS Ti layer and completely covered the piece. Primary human osteoblasts were seeded onto biomaterials and in vitro cell experiments provided evidence to confirm that nanostructured anatase coatings deposited by cold gas spray improve the performance of PEEK implants. © 2014 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 102B: 1537–1543, 2014.
Detecting synoptic warming trends across the US Midwest and implications to human health and heat‐related mortality
Authors: Vanos J. K. , Kalkstein L. S. , Sanford T. J. 
Published: March 2014

ABSTRACTThis paper highlights and expands on the extensive work concerning extreme heat events, and the environmental and societal factors that affect human health. Selections of this work were presented originally in a Union of Concerned Scientists public report (‘Heat in the Heartland’). As humans respond concomitantly to a suite of meteorological variables, we accordingly aim to examine summertime frequencies and characteristics of select synoptic weather types in the Midwestern United States, particularly those associated with elevated health impacts risk. We analyse five major urban centres, paired with five nearby smaller cities, to investigate the potential relative differences due to urban form and size. In virtually all of these locales, the frequency of health‐debilitating hot weather types has increased in the six most recent decades, with many of these also demonstrating statistically significant upward trends in air and dew point temperatures. This is most prevalent for overnight temperatures, where the hottest weather types display increasing overnight temperatures in both large and small cities, thus causing the diurnal temperature ranges to decrease. Furthermore, the prevalence of three or more consecutive runs of these days is on the rise, with all five large cities experiencing a higher number of heat waves today than in the late 1940s. We emphasize the importance of city‐level efforts to assist in minimizing future climate‐related health risks. Finally, we demonstrate the increasing human mortality response in one select city (Detroit, MI), which is estimated without the presence of city‐level efforts, targeted interventions, adaptation strategies, or physiological acclimatization. This highlights the importance of providing accurate heat‐health warnings to the public, and provides essential understanding of the Midwest US region's summertime climate trends.
Attention Bias Variability and Symptoms of Posttraumatic Stress Disorder
Authors: Iacoviello Brian M. , Wu Gang , Abend Rany , Murrough James W. , Feder Adriana , Fruchter Eyal , Levinstein Yoav , Wald Ilan , Bailey Christopher R. , Pine Daniel S. , Neumeister Alexander , Bar‐Haim Yair , Charney Dennis S. 
Published: March 2014

AbstractCognitive theories implicate information‐processing biases in the etiology of anxiety disorders. Results of attention‐bias studies in posttraumatic stress disorder (PTSD) have been inconsistent, suggesting biases towards and away from threat. Within‐subject variability of attention biases in posttraumatic patients may be a useful marker for attentional control impairment and the development of posttrauma symptoms. This study reports 2 experiments investigating threat‐related attention biases, mood and anxiety symptoms, and attention‐bias variability following trauma. Experiment 1 included 3 groups in a cross‐sectional design: (a) PTSD, (b) trauma‐exposed without PTSD, and (c) healthy controls with no trauma or Axis I diagnoses. Greater attention‐bias variability was found in the PTSD group compared to the other 2 groups ; attention‐bias variability was significantly and positively correlated (r = .37) with PTSD symptoms. Experiment 2 evaluated combat‐exposed and nonexposed soldiers before and during deployment. Attention‐bias variability did not differentiate groups before deployment, but did differentiate groups during deployment ; increased variability was observed in groups with acute posttraumatic stress symptoms and acute depression symptoms only. Attention‐bias variability could be a useful marker for attentional impairment related to threat cues associated with mood and anxiety symptoms after trauma exposure.
A simple acquisition strategy to avoid off‐resonance blurring in spiral imaging with redundant spiral‐in/out k‐space trajectories
Authors: Fielden Samuel W. , Meyer Craig H. 
Published: March 2014

PurposeThe major hurdle to widespread adoption of spiral trajectories has been their poor off‐resonance performance. Here we present a self‐correcting spiral k‐space trajectory that avoids much of the well‐known spiral blurring during data acquisition.Theory and MethodsIn comparison with a traditional spiral‐out trajectory, the spiral‐in/out trajectory has improved off‐resonance performance. By combining two spiral‐in/out acquisitions, one rotated 180° in k‐space compared with the other, multishot spiral‐in/out artifacts are eliminated. A phantom was scanned with the center frequency manually tuned 20, 40, 80, and 160 Hz off‐resonance with both a spiral‐out gradient echo sequence and the redundant spiral‐in/out sequence. The phantom was also imaged in an oblique orientation in order to demonstrate improved concomitant gradient field performance of the sequence. Additionally, the trajectory was incorporated into a spiral turbo spin echo sequence for brain imaging.ResultsPhantom studies with manually tuned off‐resonance agree well with theoretical calculations, showing that moderate off‐resonance is well‐corrected by this acquisition scheme. Blur due to concomitant fields is reduced, and good results are obtained in vivo.ConclusionThe redundant spiral‐in/out trajectory results in less image blur for a given readout length than a traditional spiral‐out scan, reducing the need for complex off‐resonance correction algorithms. Magn Reson Med 73:704–710, 2015. © 2014 Wiley Periodicals, Inc.
Focused screening of a panel of cancer‐related genetic polymorphisms reveals new susceptibility loci for pediatric acute lymphoblastic leukemia
Authors: Offenmüller Sonja , Ravindranath Yadddanapudi , Goyette Gerard , Kanakapalli Deepa , Miller Kathryn S. , Brecht Ines B. , Zolk Oliver 
Published: March 2014

BackgroundA genetic predisposition to acute lymphoblastic leukemia (ALL) in childhood is well established. Currently known risk loci, however, explain only one third of the estimated total risk related to common genetic variations.ProcedureWe genotyped 1,421 polymorphisms in 407 candidate genes from the SNP500Cancer database (National Cancer Institute) using the Illumina Cancer SNP Panel. We investigated 78 cases (aged 0–19 years at diagnosis, and mixed ethnic background) of childhood B‐precursor ALL and compared genotype data with those of 1,417 HapMap controls. To account for the ethnic diversity of the study population, structured association by genetically matching cases and controls using identity‐by‐state similarity was used. Case‐control association analyses were performed using Cochran–Mantel–Haenszel tests, adjusted for the population substructure.ResultsCommon variations rs6966 (3′ UTR of PPP1R13L, chr 19q13.32, P = 4.55 × 10−9) and rs414580 (intron 2 of MSR1, chr 8p22, P = 6.09 × 10−8) were significantly associated with ALL. These SNPs remained significant after adjustment for multiple testing. The SNP rs6966 tags a haplotype block which includes SNPs in PPP1R13L and ERCC2 genes, which are related to DNA repair and cell survival. rs6966 and rs414580 conferred allelic odds ratios of 3.74 (95% confidence interval [CI] 2.31–6.04) and 3.93 (95% CI 2.31–6.69), respectively.ConclusionsThese findings reveal two independent novel susceptibility loci for childhood ALL. Pediatr Blood Cancer 2014; 61:1411–1415. © 2014 Wiley Periodicals, Inc.
Parking Belval‐Université – ein P&R‐Parkhaus, das die Grenzen in Europa neu definiert
Authors: Schäfer Markus , Widong Marc , Klein Claude 
Published: March 2014

AbstractDie Verkehrspolitik in Luxemburg sieht das Erstellen eines möglichst dichten Netzes an öffentlichen Verkehrsmitteln vor. Autofahrer, vor allem die Vielzahl der Grenzgänger aus dem angrenzenden Ausland, sollen bereits grenznah auf die Bahn umsteigen, um somit das Straßennetz über die Grenzen von Luxemburg hinaus zu entlasten. Im Jahr 2013 wurde mit der Eröffnung das Parkhauses Belval‐Université das erste einer Reihe geplanter Park Parking Belval‐Université – A Park and Rail project is defining new boarders in Europe. Transport policy in Luxembourg provides the realization of a dense network of public transport. Motorists, especially the large number of commuters from the neighbor countries, should already change close to the borders to public traffic – especially to train. By that it is possible to relieve the national highways and also those in bordering regions. With the start into service of the new multi‐storey car park Belval‐Université in 2013, the first of a series of planned Park
Purification of G1 daughter cells from different Saccharomycetes species through an optimized centrifugal elutriation procedure
Authors: Marbouty Martial , Ermont Caroline , Dujon Bernard , Richard Guy‐Franck , Koszul Romain 
Published: March 2014

AbstractCentrifugal elutriation discriminates cells according to their sedimentation coefficients, generating homogeneous samples well suited for genomic comparative approaches. It can, for instance, isolate G1 daughter cells from a Saccharomyces cerevisiae unsynchronized population, alleviating ageing and cell‐cycle biases when conducting genome‐wide/single‐cell studies. The present report describes a straightforward and robust procedure to determine whether a cell population of virtually any yeast species can be efficiently elutriated, while offering solutions to optimize success. This approach was used to characterize elutriation parameters and S‐phase progression of four yeast species (S. cerevisiae, Candida glabrata, Lachancea kluyveri and Pichia sorbitophila) and could theoretically be applied to any culture of single, individual cells. Copyright © 2014 John Wiley & Sons, Ltd.
Coordinated Lot-sizing and Dynamic Pricing under a Supplier All-units Quantity Discount
Authors: Transchel Sandra , Mirner Stefan 
Published: March 2014

AbstractWe consider an economic order quantity model where the supplier offers an all-units quantity discount and a price sensitive customer demand. We compare a decentralized decision framework where selling price and replenishment policy are determined independently to simultaneous decision making. Constant and dynamic pricing are distinguished. We derive structural properties and develop algorithms that determine the optimal pricing and replenishment policy and show how quantity discounts not only influence the purchasing strategy but also the pricing policy. A sensitivity analysis indicates the impact of the fixed-holding cost ratio, the discount policy, and the customers’ price sensitivity on the optimal decisions.