bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessment of Physiological/Toxicological Effects of Camel Milk and Urine on Wistar Rats: A Study on Weight Gain, Haematological, Biochemical, and Histopathological Changes
Authors: Aremu Abdulfatai , Oderinde Hakeemat Moyosore , Akorede Ganiu Jimoh , Olatunji Aishat Omobolanle , Basiru Afisu , Ahmed Akeem Olayiwola 
Published: August 2024

Study’s Excerpt/Novelty

This study comprehensively evaluates the physiological effects of camel milk and urine on Wistar rats, providing new insights into their safety and potential health benefits.
It uniquely demonstrates that while camel milk and urine independently show some positive physiological impacts, their combination may induce adverse effects, particularly evident through significant changes in body weight, blood parameters, and histopathological lesions.
The findings highlight the importance of assessing the safety and efficacy of traditional remedies in isolation and combination, contributing valuable data to the field of ethnopharmacology and veterinary medicine.

Full Abstract
This experiment was steered to observe the safety evaluation of camel milk and its urine on the physiological indices of experimental rats. Four groups of twenty Wistar rats each were formed: Group 1 (Control), 2 milk (2 ml/100 g), 3 (2 ml/100 g), and 4 (milk/urine combination). The result showed that all treatment groups experienced a significantly decreased body weight gain across day 1-14, which significantly increased between day 18-21, except for group 4, which decreased significantly. The PVC, RBC, and haemoglobin increased non-significantly in group 2 and decreased in groups 3 and 4. WBC decreased significantly in milk/urine combination compared to other treatment groups. Neutrophils, Lymphocytes, and Monocytes did not show significant alteration across all the treatment groups. ALT decreased non-significantly (p>0.05) in all the treatment groups, while AST showed non-significant increased values in groups 2 and 3 except in group 4, which decreased significantly. Urea and creatinine decreased significantly (p<0.05) in all the treatment groups. Cl- of group 3 decreased significantly (p<0.05), while it increased significantly (p<0.05) in group 4. Na+ showed significantly increased values across all the treatment groups while Bicarbonate decreased significantly in all the treatments. Ca2+ increased non-significantly. Histopathology results showed that group 4 has arrays of lesions compared to those treated separately. There was no observable lesion in these organs in group-2. It can be concluded that camel milk and its urine might have some beneficial effects when dosed separately, but they might predispose to harmful effects when combined.
Malaria Prevalence and Associated Risk Factors among Pregnant Women Attending Wadata and Lafia North Primary Health Care Centers Lafia, Nasarawa State, Nigeria
Authors: Maikentii James Ishaku , Umar Ruqayyat Musa , Ombugadu Akwashiki , Aimankhu Peter Oseghale , Yusuf Kuna Samaila , Mamman Atnaga Shadrach , Dakum Yakob Dalis 
Published: August 2024

Study’s Excerpt/Novelty

This study investigates the prevalence of malaria among pregnant women in Lafia, Nasarawa state, Nigeria, revealing significant associations between infection rates and educational level, occupational status, and age.
The results demonstrate the highest prevalence of Plasmodium infection among women aged 31–35 and those with tertiary education, while civil servants showed significantly higher infection rates compared to other occupational groups.
Additionally, the study highlights differences in malaria prevalence related to net ownership and usage, providing critical insights into targeted public health interventions for reducing malaria risk in this vulnerable population.

Full Abstract
Plasmodium infection in pregnant women poses significant public health challenges, potentially leading to adverse outcomes for both mothers and their babies. This study investigated the prevalence of malaria and associated risk factors among 144 pregnant women attending a prenatal clinic at Wadata and Lafia North Primary Health Care Centers in Lafia, Nasarawa state, Nigeria. Using thick and thin blood smears and structured questionnaires, we found that 15.79% of the women were infected with Plasmodium. Even though Wadata Primary Health Centre recorded a higher prevalence (15.87%) than Lafia North (15.69%), no difference was observed (ᵪ2= 0.0012658, df = 1, P = 0.9716). Plasmodium infection prevalence was highest (27.27%) in the age range 31–35 and lowest in the age ranges15-20 (7.14%), while age above 36 years recorded negative infection. The highest prevalence (19.04%) was observed in women who acquired a tertiary education, then those who acquired a primary education (18.75%) or a secondary (17.64%) or those with no formal education (4.54%), and these differences in the prevalence with respect to the educational level varied significantly (ᵪ2= 9.8462, df = 3, P = 0.01992). A significant difference (ᵪ2= 27.516, df = 4, P = 1.563x10-5) was observed in civil servants (25.00%) compared to traders (15.15%), other employees (14.28%), artisans (8.00%), as well as the farmers who were never infected at all. The prevalence of malaria among women who own a net was 17.1% in Lafia and 15% in Wadata. While those sleeping under it were 5 (18.2%) in Lafia North and 3 (8.82%) in Wadata. The prevalence among women who had prior knowledge of using a treated bed net as a malaria protective measure in Lafia North was 6(13.3%), while in Wadata, it was 6(14.7%).
Assessment of Indoor Resting Density of Female Mosquitoes in Dutse, Jigawa State, Nigeria: Implications for Disease Transmission and Community-Based Mosquito Control Measures
Authors: Sadiq Abubakar Abubakar , Ishaq Shamsu ibrahim , Akilu Humaira Liman 
Published: August 2024

Study’s Excerpt/Novelty

This study presents insights into the seasonal variations in Indoor Resting Density (IRD) of female mosquitoes in Dutse L.G.A., Jigawa State, providing critical data for targeted vector control interventions.
By employing the Pythrum Spray Caught method across three communities over seven months, it uniquely identifies the optimal timing for insecticide spraying, particularly in April, when the IRD exceeds the epidemic threshold.
The research underscores the necessity of community involvement in mosquito control measures, paving the way for more effective and localized vector management strategies.

Full Abstract
Mosquito is a major vector of humans and other animals globally, especially in Africa. This study assessed female mosquitoes' Indoor Resting Density (IRD) in Dutse L.G.A., Jigawa State. Mosquitoes were collected using the Pythrum Spray Caught method from three communities (Gurungu, Baranda, and Warwade) for seven months (April to October 2022). The highest IRD of female Anopheles was recorded in September at Baranda (33.3) and the lowest IRD at Gurungu (0.0) in June. The highest IRD of Female Culex was recorded in July at Gurungu (13.7), while the lowest was recorded in June at Baranda (0) and Warwade. The findings of this study revealed the idle spraying time of insecticide in all the study sites, which was found to be April because the IRD was beyond the normal (0.05)per house, which was related to epidemic transmission of the diseases. I recommended further study on community involvement in mosquito control measures.
Redescription of a small Caviidae (Rodentia: Hystricognathi) from the Neogene of northwestern Argentina and its systematic implications
Authors: MADOZZO JAÉN María Carolina , PÉREZ María Encarnación 
Published: August 2024

The understanding of the taxonomy, diversity, and evolutionary patterns of caviids in northwestern Argentina is still in the process of development. This paper presents new insights into the systematic and evolution of Orthomyctera andina (Rovereto, 1914), one of the most abundant species within Caviidae Fischer de Waldheim, 1817, in the fossil record of this region. A comprehensive anatomical description and taxonomic review of Orthomyctera andina in a phylogenetic context is provided. Moreover, it includes a redescription of the type specimen of Orthomyctera rigens (Ameghino, 1888). The taxonomical results confirm that O. andina belongs to a different genus: Orocavia (Kraglievich, 1932). The phylogenetic analysis further confirms the placement of both species within Caviinae Fischer de Waldheim, 1817. Orthomyctera andina is the sister taxon of the clade that includes ­Microcavia Gervais & Ameghino, 1880, Dolicavia Ameghino, 1916, Neocavia Kraglievich, 1932, and Orthomyctera Ameghino, 1889. It is supported by a combination of plesiomorphic characters (e.g. furrow opposite to hypoflexus/id in molariforms) shared with basal taxa and Dolichotinae Pocock, 1922 and derived characters (such as a terreced palate, external auditory meatus below the occlusal surface , length of p4-m1 shorter than length of m2-m3) shared with Caviinae. This study aims to elucidate the taxonomic status of these poorly known rodents and their relationships within Caviidae. Additionally, it incorporates a biogeographic analysis of caviomorph communities from the late Neogene in Argentina.
Hubungan Adverse Childhood Experience (ACE) dengan Psychological Distress pada Mahasiswa Universitas Negeri Padang
Authors: Islami Azizah , Rinaldi Rinaldi 
Published: August 2024

As a student, students are required to be able to complete the lecture level with satisfactory grades. In reality, many students are not only responsible for studying but also have other responsibilities such as organisations, work and family. Common demands experienced by students such as getting good grades, getting a job, building a career and some are also required to get married immediately. Demands that exceed the limits of the ability of students will trigger the onset of psychological distress. Psychological distress is a condition or unpleasant feeling that is felt subjectively by individuals. Distress can be caused by situational factors, namely adverse childhood experience. This study aims to determine the relationship between Adverse Childhood Experience (ACE) and Psychological Distress in Padang State University Students. This study uses quantitative research methods with a correlational approach. Sampling using purposive sampling technique with a total of 100 respondents. Data analysis using product moment correlation. The results showed that ACE and psychological distress had a positive relationship with a p value of 0, 00> 0.05 with a pearson correlation value of 0.587.
Global Study on the Accuracy of Human Epidermal Growth Factor Receptor 2-Low Diagnosis in Breast Cancer
Authors: Rüschoff Josef , Penner Alexander , Ellis Ian O. , Hammond M. Elizabeth Hale , Lebeau Annette , Osamura Robert Y. , Penault-Llorca Fréderique , Rojo Federico , Desai Chirag , Moh Akira , Atkey Neil , Baenfer Gudrun , Scheel Andreas H. , D’Arrigo Corrado , Schildhaus Hans-Ulrich , Viale Giuseppe ,   HER2-Low Study Group
Published: August 2024

Context.—
Recently, a new type of antibody-drug conjugate, trastuzumab-deruxtecan (T-DXd), has been approved for the treatment of metastatic breast cancer with low level of human epidermal growth factor receptor 2 (HER2) gene expression. Thereby, eligibility relies on an accurate diagnosis of HER2-low status defined by immunohistochemistry IHC 1+/2+ with no gene amplification.

Objective.—
To assess pathologists’ accuracy and training efficacy in the diagnosis of HER2-low.

Design.—
Agreement rates of HER2-low scoring in breast cancer tissue were assessed between expert consensus and real-world pathologists (n = 77 from 14 countries) before and after a specific 4-hour training for HER2-low detection. Two assays were evaluated, the Ventana Pathway 4B5 CDx and the Dako HercepTest (polyclonal). Concordance of the pathologists with consensus score and efficacy of training were measured by Cohen κ, overall rater agreement, and receiver operating characteristic (ROC) curve statistics.

Results.—
In the Ventana 4B5 HER2-low category, baseline agreement rates were &gt;80% but &lt;90%. Negative percentage agreement was improved from 80.6% to 91.1% by training. In the HER2-0 category, positive percentage agreement (74.6%) was the only parameter below the 80% benchmark but was significantly improved to 89.2% after training. Training efficacy was confirmed by ROC curve analysis, which shows improvement for the identification of HER2-0 and HER2-low cases. Finally, in-depth examination of cases with discordant HER2 status disclosed specific issues of HER2-low underscoring and overscoring.

Conclusions.—
The ability of pathologists to achieve acceptable diagnostic accuracy in identifying patients with HER2-low breast cancer could be enhanced by short-term training. Potential routes to improve the quality of HER2-low scoring in clinical practice have been identified.
Pengembangan Media E-Learning Berbasis Weblog dengan Pendekatan Contextual Teaching and Learning (CTL) pada Materi Laju Reaksi
Authors: Rumahorbo Shinta , Nurfajriani Nurfajriani 
Published: August 2024

This study aims to find out the analysis of media needs, look for e-learning media based on weblogs with a CTL approach on reaction rates developed based on BSNP and knowing students' responses to webblog-based e-learning media with a CTL approach on the reaction rate material. Analysis of media needs was carried out by interviewing the chemistry class teacher of SMAN 1 Sibolga. This study uses the method (R&D) with the ADDIE development model covering the stages (analysis, design, development, implementation and evaluation). The developed media product was validated by 3 expert validators consisting of 2 chemistry lecturers and 1 chemistry teacher. The average result of the validation of the weblog-based e-learning media with the CTL approach that has been developed by chemistry lecturers and teachers is 3.70 in the very feasible category and material validation is 3.71 in the very feasible category and does not need to be revised. The assessment of the percentage of student responses to the web-based e-learning media developed was 74.5% with high response criteria
SINERGITAS BIMBINGAN KONSELING DAN GURU PENDIDIKAN AGAMA ISLAM DALAM MENGEMBANGKAN KARAKTER SISWA SMK NEGERI 1 AMPEK ANGKEK
Authors: Fina Diningsih Lestari  
Published: August 2024

Bimbingan dan Konseling dan guru pendidikan Agama Islam disekolah sangat berpengaruh terhadap karakter siswa, keduanya memiliki tanggungjawab yang sama terhadap pendidikan karakter siswa yang baik serta mempunyai keberhasilan penyelenggaraan pendidikan. Dalam artikel ini penulis menggunakan metode kualitatif deskriptif, di mana proses atau upaya yang dilakukan oleh bimbingan dan konseling serta guru Pendidikan Agama Islam. Teknik yang digunakan penulis yaitu wawancara dan observasi. Hasil penelitian menunjukkan hasil yang positif mengenai kerja sama atau sinergi yang dilakukan oleh bimbingan dan konseling serta guru Pendidikan Agama Islam dalam pengembangan karakter melalui interaksi,dan program-program bimbingan konseling, serta program sekolah yang berkaitan dengan pendidikan karakter.
PENGARUH TONTONAN YOUTUBE TERHADAP PEMEROLEHAN BAHASA ASING PADA REMAJA USIA 16 TAHUN
Authors: Muhamad Yuda Irawan  , Intan Sari Ramdhani  
Published: August 2024

Bahasa merupakan alat komunikasi utama yang digunakan sehari-hari oleh setiap individu. Berbagai tontonan yang ditonton setiap remaja Indonesia di YouTube sangat beragam. YouTube juga bisa menjadi sarana pemerolehan bahasa kedua karena keberagaman video yang terdapat di dalam aplikasi tersebut berasal dari berbagai penjuru dunia. Dengan demikian, tujuan penelitian ini adalah sebagai berikut: 1) Mengetahui pengaruh tontonan dalam YouTube dalam kemampuan pemerolehan bahasa asing pada remaja berusia 16 tahun. 2) Memahami faktor penyebab adanya pengaruh tontonan YouTube terhadap kemampuan pemerolehan Bahasa asing pada remaja usia berusia 16 tahun. Penelitian ini menggunakan metode kualitatif deskriptif. Teknik pengumpulan data berupa wawancara. Hasil penelitian ini menunjukkan bahwa tontonan berbahasa asing di YouTube dapat berpengaruh terhadap kemampuan pemerolehan bahasa asing Zeedee.
MENINGKATKAN HASIL BELAJAR MATEMATIKA MATERI PERSAMAAN DAN FUNGSI KUADRAT MELALUI PENGGUNAAN MULTIMEDIA
Authors: Endang Rahmijati  
Published: August 2024

The goals of this research are: To know the implementation of multimedia at Madrasah Tsanawiyah Negeri 39 Jakarta; To know mathematic learning of equation and square functional of students at Madrasah Tsanawiyah Negeri 39 Jakarta; To know the implementation of multimedia to increase mathematic learning of equation and square functional of Madrasah Tsanawiyah Negeri 39 Jakarta.
Type of the research is action research. The subject of this research is the students at Madrasah Tsanawiyah Negeri 39 Jakarta. Implementation of this research is to do 2 cycles, which consist of four activities, that (a) planning, (b) implementing, (c) observing, (d) reflecting.
The using of multimedia for students class IX-3 Madrasah Tsanawiyah Negeri 39 Jakarta in the first is difficult. After giving comprehenshive guidance, finally in second cycle runs well. The result of mathematic learning of equation and square functional for students class IX-3 Madrasah Tsanawiyah Negeri 39 Jakarta, before cycle is 65,71% could meet the criteria of success, next in first cycle increase become 68,57%, in the second cycle become 88,57%. Based on the result of research, it can be known the result of mathematic learning of equation and square functional for students class IX-3 Madrasah Tsanawiyah Negeri 39 Jakarta by using multimedia, from the first cycle to the second cycle on going increase, average score is 78,51 increase become 81,49. So there are increase the mathematic learning 2,98. The writer can conclude that there is significant between mathematic learning and multimedia.
PENGARUH STRATEGI PEMBELAJARAN PROBLEM BASED LEARNING BERBANTUAN MEDIA AUDIOVISUAL TERHADAP KEMAMPUAN MENULIS TEKS PERSUASI PADA SISWA KELAS VIII SMP NEGERI 1 GALANG
Authors: Nur Hasnah  
Published: August 2024

This research aims to describe the effect of problem-based learning strategy assisted by visual media on the ability to write persuasive texts among students in class VIII of SMP Negeri 1 Galang. iThe subjects of this research were 24 students of class VIII-5 (control class) and 28 students of class VIII-7 (experimental class) of SMP Negeri 1 Galang, which were determined by cluster random sampling. The method used in this research is the experimental method with the Posttest-Only Control design. The instrument used in this research is the test (posttest). From the data analysis, it was obtained that the mean value of the posttest in the control class was 62 and the standard deviation was 7.59, while the mean value of the posttest in the experimental class was 88.64 and the standard deviation was 6.18. Before conducting the hypothesis test, the analysis requirements were tested, namely the normality test and the homogeneity test. Based on the results of data analysis, it was found that the data of the posttest of the control class and the experimental class were normally distributed and homogeneous. iConsulted itcount with ittable at the significance level of 0.05 with dk=n1 + n2 -2 = 28 + 24 - 2= 50 obtained ttable = 1.675905. Because tcounti> ttabel 13.95 > 1.68, so this hypothesis (Ho) is rejected and the alternative hypothesis (Ha) is accepted. The result of the hypothesis test shows that the problem-based learning strategy assisted by visual media has a positive influence on the ability to write persuasive texts among students in class VIII of SMP Negeri 1 Galang.
Upaya Meningkatkan Kemampuan Berbahasa Melalui Metode Bercerita Dengan Media Ritatoon Di Paud Qaireen T.A 2022/2023
Authors: Khairani Khairani  , Rahmadi Ali  , Juli Yanti Harahap  
Published: August 2024

This study aims to determine how to improve children's language skills through storytelling methods with ritatoon media for children aged 5-6 years at Qaireen PAUD. This research is a classroom action research (PTK) that uses the Kemmis and Mc Tanggart model. The subjects of this study were 20 children, consisting of 10 boys and 10 girls. Data collection techniques used in this study were observation of improving children's language skills through storytelling methods with ritatoon media, teacher and child activities and documentation. The data analysis technique used in this research is descriptive qualitative. Based on the results of the study, it is known that there is an increase in children's language skills through storytelling methods with ritatoon media. This is known from the average child who gets the level of achievement of children developing as expected (BSH) and developing very well (BSB) in the Pre-Cycle with an average percentage of 8.75%, then in Cycle I the level of achievement of children developing as expected (BSH) and developing very well (BSB) with an average percentage of 53.75%, so we can see an increase in Pre-cycle to Cycle I by (45%) However, in cycle I it has not developed well so it is continued to Cycle II. The level of achievement of children developing as expected (BSH) and developing very well (BSB) Cycle II with an average percentage of 95%. Based on the results of the study it can be concluded that ritatoon media can improve the language skills of children aged 5-6 years. The increase occurred, because in telling stories using ritatoon which had not previously been applied in the school, big ritatoon special characteristics are colorful, interesting pictures, as well as words that can be repeated, have predictable properties, and are fun.
Faktor-Faktor Yang Mempengaruhi Minat Baca Siswa Kelas II Di SDN 2 Kedungsarimulyo
Authors: Eka Nanda Banowati  , Mudrikatunnisa Mudrikatunnisa  , Alvita Rizki Maula  , Nur Fajrie  
Published: August 2024

Minat adalah sesuatu yang sangat penting bagi seseorang untuk melakukan suatu aktivitas. Dengan minat orang akan berusaha mencapai tujuannya. Oleh karena itu minat dikatakan sebagai salah satu aspek psikis manusia yang dapat mendorong untuk mencapai tujuan. Ada dua aspek yang dikandung oleh minat antara lain aspek kognitif dan aspek afektif. Hasil observasi dan wawancara dengan subjek, serta wawancara dengan wali kelas dan guru bidang studi lainnya untuk mengetahui penyebab kesulitan belajar dan prestasi akademik rendah yang dimiliki subjek. Menumbuhkan minat baca merupakan sebuah proses yang tidak muncul begitu saja, tetapi merupakan proses yang harus ditumbuhkan sejak anak usia dini.