bluuebunny/crossref_metadata_2025_split huggingface dataset:
Draft Genome Sequences of 18 Oral Streptococcus Strains That Encode Amylase-Binding Proteins
Authors: Sabharwal Amarpreet , Liao Yu-Chieh , Lin Hsin-Hung , Haase Elaine M. , Scannapieco Frank A. 
Published: May 2015

ABSTRACT
A number of commensal oral streptococcal species produce a heterogeneous group of proteins that mediate binding of salivary α-amylase. This interaction likely influences streptococcal colonization of the oral cavity. Here, we present draft genome sequences of several strains of oral streptococcal species that bind human salivary amylase.
Draft Genome Sequence of Mycobacterium bovis Strain SP38, a Pathogenic Bacterium Isolated from a Bovine in Brazil
Authors: Guimaraes Ana Marcia Sa , Zimpel Cristina Kraemer , Ikuta Cássia Yumi , do Nascimento Naíla Cannes , dos Santos Andrea Pires , Messick Joanne Belle , Heinemann Marcos Bryan , Ferreira Neto José Soares , Brandão Paulo Eduardo 
Published: May 2015

ABSTRACT

We report a draft genome sequence of
Mycobacterium bovis
strain SP38, isolated from the lungs of a cow in Brazil. The assembly of reads resulted in 36 contigs in a total of approximately 4.37 Mb. Comparison of
M. bovis
strains sequenced to date will aid in understanding bovine tuberculosis in Brazil.
Draft Genome Sequence of Jeotgalibacillus soli DSM 23228, a Bacterium Isolated from Alkaline Sandy Soil
Authors: Goh Kian Mau , Chan Kok-Gan , Yaakop Amira Suriaty , Chan Chia Sing , Ee Robson , Tan Wen-Si , Gan Han Ming 
Published: May 2015

ABSTRACT

Jeotgalibacillus soli
, a bacterium capable of degrading
N
-acyl homoserine lactone, was isolated from a soil sample in Portugal.
J. soli
constitutes the only
Jeotgalibacillus
species isolated from a non-marine source. Here, the draft genome, several interesting glycosyl hydrolases, and its putative
N
-acyl homoserine lactonases are presented.
Draft Genome Sequence of New Leprosy Agent
Mycobacterium lepromatosis
Authors: Han Xiang Y. , Mistry Nipun A. , Thompson Erika J. , Tang Hong-Li , Khanna Kanhav , Zhang Li 
Published: May 2015

ABSTRACT

Mycobacterium lepromatosis
is a newly discovered cause of leprosy. Here, we present a near-complete genome of
M. lepromatosis
from strain FJ924 obtained from a patient who died of leprosy. The genome contained 3,215,823 nucleotides and matched ~87% with the
Mycobacterium leprae
genome. This genome is likely the smallest of all mycobacterial genomes known to date.
Complete Genome Sequence of Pseudomonas aeruginosa Strain 8380, Isolated from the Human Gut
Authors: Ichise Yu-ki , Kosuge Takehide , Uwate Maki , Nakae Taiji , Maseda Hideaki 
Published: May 2015

ABSTRACT

Pseudomonas aeruginosa
shows multidrug resistance, which is mainly attributable to its expression of xenobiotic efflux pumps. However, it is unclear how silent pumps are expressed in clinical isolates. Here, we sequenced the complete genome of
P. aeruginosa
strain 8380, which was isolated from a human gut.
Draft Genome Sequences of Corynebacterium kroppenstedtii CNM633/14 and CNM632/14, Multidrug-Resistant and Antibiotic-Sensitive Isolates from Nodules of Granulomatous Mastitis Patients
Authors: Fernández-Natal Maria Isabel , Soriano Francisco , Ariza-Miguel Jaime , Marrodan-Ciordia Teresa , Acedo Alberto , Hernandez Marta , Tauch Andreas , Rodríguez-Lázaro David 
Published: May 2015

ABSTRACT

Corynebacterium kroppenstedtii
has been associated with infections of the female breast. Genome sequencing of two strains revealed a specific genomic island in the multidrug-resistant isolate CNM633/14 with similarity to the R plasmid pJA144188 of
Corynebacterium resistens
DSM 45100, being indicative of the horizontal transfer of antibiotic resistance genes to
C. kroppenstedtii
.
Part 2: Indexes
Authors: Spamer Earle E. 
Published: May 2015

Abstract
Every animal generic name in the Grand Canyon literature base is included in this list. Complete bibliographical citations for individual entires can be found in the bibliography (Part 1). Page and figure citations are listed for every mention of a generic name without an included species–as a generic name alone, in conjunction with the specific indication “sp.,” in comparison with a species (“cf.”), or as an indication of affinity to a species (“aff.”). When appropriate, cross-indexes appear to the index to animal species (Index 3). Genera that have never appeared in the Grand Canyon regional literature without an accompanying specific name are included in this index, but with a cross-reference to Index 3.
Part 1: Bibliography
Authors: Spamer Earle E. 
Published: May 2015

AbstractThis bibliography is comprehensive for the entire volume. In addition to references that discuss particular systematic taxa , it also includes citations of references that in some way discuss paleontology in the Grsad Canyon region without naming any systematic taxa. Citations provide complete bibliographical data in Mfioort of abbreviated citations in the indexes that follow in Part 2. References that are flagged by a triangle () indicate publications that wholly or in part discuss fossils derived from Tertiary that are important in the interpretation of the development of the Grand Canyon; these occurrences are not neceeaarily at or near the Grand Canyon.These are lists of genera and species reported from publications th. cover areas greater than that covered by' these indaexcluded from these lists (thus thes- lists do not necessarily cite every). The taxa sre listed alphabeticaity, first listing Animalia,then AcriIIrdaa, dofouill. Taxa that are cited only as genera (e.g., Pinus sp.) are iDduded 0lIl,IaaYe included in them (in the cited publication). The systematic placemelll of tau foIlowidaelCbeme explainedin the "Scopeand Organization" section of this volume. In I few inItaDceI, it to update the identification under which the taxon was originally described; piItiaaArIy in the taIeI of Proterozoic fossils that were originally described under metazoan groups that fint evolved durin, the Paleozoic.
Airway foreign body aspiration: common, yet easily overlooked! Two interesting cases
Authors: Møller Janne , Rasmussen Finn , Hilberg Ole , Løkke Anders 
Published: May 2015

Two cases: A 66-year-old woman was referred to the hospital due to dyspnoea and cough. Seven months prior to referral, the patient had choked on a chunk of nut and grain-filled bread. She had daily cough and dyspnoea. The patient was convinced of an airway foreign body and she contacted her general practitioner and the emergency service several times; they all found this unlikely. Fibre optic bronchoscopy revealed two obstructing nut-like foreign bodies in the right upper and lower lobe, respectively.A 77-year-old man with sarcoidosis developed increased dyspnoea and sputum production. Three weeks earlier, the patient had choked on a magnesium tablet. Everyone was convinced that the tablet had dissolved. Infection was suspected. Chest CT scan was performed showing no obvious signs of infection or progression in sarcoidosis. After the CT scan, the patient coughed up the remains of the tablet and his symptoms resolved. Retrospective evaluation of the CT scan revealed the tablet.
Paediatric fibroepithelial lesions revisited: pathological insights
Authors: Tay Timothy Kwang Yong , Chang Kenneth Tou En , Thike Aye Aye , Tan Puay Hoon 
Published: May 2015

AimTo review the clinicopathological features of fibroepithelial neoplasms of the breast diagnosed by the paediatric pathology service in a children's hospital.MethodsFiles of the Department of Pathology and Laboratory Medicine, Kandang Kerbau Women's and Children's Hospital, were searched for breast fibroepithelial neoplasms diagnosed between January 2002 and December 2012. Tumour size and macroscopic findings were obtained from surgical pathology reports while clinical features were determined from clinical files. Histological slides were reviewed and microscopic parameters documented. Findings were tabulated and analysed using statistical methods.Results68 fibroepithelial neoplasms from 53 female subjects were studied. There were 27 (39.7%) fibroadenomas, 32 (47.1%) juvenile fibroadenomas, 3 (4.4%) cellular fibroadenomas, 3 (4.4%) benign phyllodes tumours with the remaining 3 (4.4%) comprising benign fibroepithelial neoplasms with focal infarction and hybrid features. Half (50%) of the tumours possessed small leaf-like fronds and a majority had at least moderate stromal cellularity (83.8%). Most tumours had no discernible stromal mitoses with only 23.5% (16/68) having ≥1 mitoses per 10 high power fields. Many (79.4%) disclosed positive surgical margins. Recurrences occurred in 8 (11.8%) cases after excision.ConclusionsMost paediatric fibroepithelial tumours showed increased stromal cellularity which did not correlate with recurrence. Leaf-like fronds were commonly seen in paediatric fibroepithelial tumours apart from phyllodes tumours. Stromal mitoses were rare and may be a better criterion for predicting recurrence.
Follow-up of intracranial aneurysms treated by a WEB flow disrupter: a comparative study of DSA and contrast-enhanced MR angiography
Authors: Mine Benjamin , Tancredi Illario , Aljishi Ali , Alghamdi Faisal , Beltran Margarita , Herchuelz Maxime , Lubicz Boris 
Published: May 2015

ObjectiveTo compare contrast-enhanced MR angiography (CE-MRA) and DSA for the follow-up of intracranial aneurysms (IAs) treated with the Woven EndoBridge embolization system DL (WEB DL; Sequent Medical, Aliso Viejo, California, USA).Materials and methodsWe retrospectively identified all patients treated with a WEB DL between November 2010 and February 2013 in 2 hospitals. The IA occlusion was graded on follow-up CE-MRA and DSA by 4 independent readers and by 2 readers reaching a consensus, respectively. Interobserver agreement for MRA and intertechnique agreement was evaluated by calculating linear weighted κ.ResultsFifteen patients with 16 IAs were included. Mean delay between MRA and DSA was 2 months (range 0–16 months). Interobserver agreement for MRA was substantial to almost perfect (κ=0.686–0.921; mean κ=0.809). Intertechnique agreement was moderate to substantial (κ=0.579–0.724; mean κ=0.669). Only three out of five inadequately occluded IAs were detected by MRA.ConclusionsCE-MRA is a useful tool for the follow-up of IAs treated with a WEB DL. However, early follow-up with DSA remains mandatory to detect inadequately occluded IAs.
Organisation of reperfusion therapy for STEMI in a developing country
Authors: Dharma Surya , Andriantoro Hananto , Dakota Iwan , Purnawan Ismi , Pratama Vireza , Isnanijah Herawati , Yamin Muhammad , Bagus Tjatur , Hartono Benny , Ratnaningsih Endang , Suling Frits , Basalamah M Abas 
Published: May 2015

ObjectiveRoutine evaluation of performance measures for the system of care for patients with ST-elevation myocardial infarction (STEMI) is needed to improve the STEMI network. We sought to evaluate the current status of reperfusion therapy for STEMI in the capital city of a developing country where a STEMI network was introduced in 2010.MethodsData were obtained from a local registry. A total of 28 812 patients admitted to the emergency department of a national cardiovascular hospital in three different periods (2007, 2010 and 2013) were retrospectively analysed; there were 2703 patients with STEMI.ResultsIn 2013 compared with 2007, there was a major increase in the number of primary percutaneous coronary interventions (PCIs) (35% vs 24%, p<0.001), and the proportion of non-reperfused patients fell (62.8% vs 67.7%, p<0.001). An improvement in the overall STEMI mortality rate was also observed (7.5% vs 11.7%, p<0.001).ConclusionsImplementation of a regional system of care for STEMI may improve utilisation of primary PCI. Future organisation of reperfusion therapy in a developing country such as Indonesia strongly calls for a strategy that focuses on prehospital care to minimise delay from the first medical contact to reperfusion therapy, and this may reduce the proportion of non-reperfused patients. These strategies are in concordance with guideline recommendations and may reduce or eliminate gaps in healthcare in developing countries, particularly the underutilisation of evidence-based therapies for patients with STEMI.Trial registration numberNCT 02319473, Clinicaltrials.gov.
Constant Time Algorithm for Computing a Collision-Free Path on R-Mesh with Path Quality Analysis
Authors: El-Boghdadi Hatem M. 
Published: May 2015

The reconfigurable mesh (R-Mesh) was shown to be a very powerful model capable of extremely fast solutions to many problems. R-Mesh has a wide range of applications such as arithmetic problems, image processing and robotics. The 2D R-Mesh was shown to be able to solve the path planning problem very fast. In this paper, we propose an algorithm to compute a collision-free path, P, between a source and a destination in an environment with the existence of obstacles. Independent of the number of obstacles, k, the proposed algorithm runs in constant time and requires O( log 2N) pre-processing time where N is the size of the R-Mesh. This is in contrast to the previous work that requires O(k) time with the same pre-processing time. We then consider the quality of the generated path. We present a constant-time modification to enhance the length of the path and analyze the generated path P in terms of the number of bends in P. We derive the number of bends in P for any set of obstacles. We also derive a necessary condition for the minimum number of bends in the path P, i.e., a lower bound on the number of bends. We finally identify a class of obstacles for which the above necessary condition is sufficient as well (tight bound).
Integrated Environmental Modelling: human decisions, human challenges
Authors: Glynn Pierre D. 
Published: May 2015

Abstract
Integrated Environmental Modelling (IEM) is an invaluable tool for understanding the complex, dynamic ecosystems that house our natural resources and control our environments. Human behaviour affects the ways in which the science of IEM is assembled and used for meaningful societal applications. In particular, human biases and heuristics reflect adaptation and experiential learning to issues with frequent, sharply distinguished, feedbacks. Unfortunately, human behaviour is not adapted to the more diffusely experienced problems that IEM typically seeks to address. Twelve biases are identified that affect IEM (and science in general). These biases are supported by personal observations and by the findings of behavioural scientists. A process for critical analysis is proposed that addresses some human challenges of IEM and solicits explicit description of (1) represented processes and information, (2) unrepresented processes and information, and (3) accounting for, and cognizance of, potential human biases. Several other suggestions are also made that generally complement maintaining attitudes of watchful humility, open-mindedness, honesty and transparent accountability. These suggestions include (1) creating a new area of study in the behavioural biogeosciences, (2) using structured processes for engaging the modelling and stakeholder communities in IEM, and (3) using ‘red teams’ to increase resilience of IEM constructs and use.
Leukoaraiosis Burden Significantly Modulates the Association Between Infarct Volume and National Institutes of Health Stroke Scale in Ischemic Stroke
Authors: Helenius Johanna , Henninger Nils 
Published: May 2015

Background and Purpose—
The National Institutes of Health Stroke Scale (NIHSS) provides a reliable, quantitative measure of ischemic stroke severity and is predicted by the infarct size. We sought to determine whether leukoaraiosis severity affects the association between infarct size and NIHSS.

Methods—
NIHSS and diffusion-weighted imaging–defined infarct volumes from 312 prospectively enrolled patients with supratentorial, ischemic strokes were analyzed. Leukoaraiosis severity was graded according to the Fazekas scale and conceptually defined as absent (0; n=44), mild (1–2; n=106), moderate (3–4; n=105), and severe (5–6; n=57). ANCOVA was used to describe the effect of leukoaraiosis on the association between infarct volume and NIHSS. Multivariable linear regression models were constructed to assess whether the association of leukoaraiosis and infarct volume on NIHSS was independent of other clinically relevant covariates.

Results—

Overall, there was a significant correlation between the infarct volume and NIHSS (
r
=0.591;
P
<0.001). This correlation significantly attenuated with increasing leukoaraiosis severity from
r
=0.786 (
P
<0.001; absent leukoaraiosis) to
r
=0.498 (
P
<0.001; severe leukoaraiosis) and as shown by ANCOVA (
P
<0.001). Leukoaraiosis (coefficient, 0.107; 95% confidence interval, 0.036–0.179; P=0.016) and infarct volume (coefficient, 0.360; 95% confidence interval, 0.305–0.416;
P
<0.001) were independently associated with a greater NIHSS deficit in the fully adjusted multivariable model.

Conclusions—
Leukoaraiosis significantly modulates the association between infarct volume and NIHSS. The clinical implications of these findings need further exploration in prospective studies but may be relevant to mitigate outcome differences in patients with stroke by aiding treatment decisions that rely on the NIHSS.
Evidence That Ly6C
hi
Monocytes Are Protective in Acute Ischemic Stroke by Promoting M2 Macrophage Polarization
Authors: Chu Hannah X. , Broughton Brad R.S. , Ah Kim Hyun , Lee Seyoung , Drummond Grant R. , Sobey Christopher G. 
Published: May 2015

Background and Purpose—

Ly6C
hi
monocytes are generally thought to exert a proinflammatory role in acute tissue injury, although their impact after injuries to the central nervous system is poorly defined. CC chemokine receptor 2 is expressed on Ly6C
hi
monocytes and plays an essential role in their extravasation and transmigration into the brain after cerebral ischemia. We used a selective CC chemokine receptor 2 antagonist, INCB3344, to assess the effect of Ly6C
hi
monocytes recruited into the brain early after ischemic stroke.

Methods—
Male C57Bl/6J mice underwent occlusion of the middle cerebral artery for 1 hour followed by 23 hours of reperfusion. Mice were administered either vehicle (dimethyl sulfoxide/carboxymethylcellulose) or INCB3344 (10, 30 or 100 mg/kg IP) 1 hour before ischemia and at 2 and 6 hours after ischemia. At 24 hours, we assessed functional outcomes, infarct volume, and quantified the immune cells in blood and brain by flow cytometry or immunofluorescence. Gene expression of selected inflammatory markers was assessed by quantitative polymerase chain reaction.

Results—

Ly6C
hi
monocytes were increased 3-fold in the blood and 10-fold in the brain after stroke, and these increases were selectively prevented by INCB3344 in a dose-dependent manner. Mice treated with INCB3344 exhibited markedly worse functional outcomes and larger infarct volumes, in association with reduced M2 polarization and increased peroxynitrite production in macrophages, compared with vehicle-treated mice.

Conclusions—

Our data suggest that Ly6C
hi
monocytes exert an acute protective effect after ischemic stroke to limit brain injury and functional deficit that involves promotion of M2 macrophage polarization.
The North China/Northeastern Asia Severe Summer Drought in 2014
Authors: Wang Huijun , He Shengping 
Published: May 2015

Abstract
In summer 2014, north China and large areas of northeastern Asia (NCNEA) suffered from the most severe drought of the past 60 years. This study indicates that the East Asian summer precipitation in 2014 exhibited a tripole anomaly, with severe negative anomalies in NCNEA, strong positive anomalies in south China, South Korea, and Japan, and intense negative anomalies in the western North Pacific. Along with the severe tripole precipitation anomalies, there were strong intensities of the Silk Road pattern, the Pacific–Japan pattern, and the Eurasian teleconnection pattern, which were responsible for the strong precipitation anomaly in 2014 through changes to the western Pacific subtropical high (WPSH) and the East Asian trough. Further analysis indicates that the sea surface temperature (SST) in the North Pacific was nearly the warmest in the past 60 years and, together with the strong SST warming in the warm pool region, thus caused the strong Pacific–Japan teleconnection pattern, southward positioning of the WPSH, and weakened East Asian summer monsoon. Additionally, the summertime sea ice cover in the Arctic Ocean was anomalous, resulting in high SST in the Laptev–Kara Sea and, hence, triggering a strong Eurasian teleconnection pattern and contributing to the severe drought of NCNEA. Furthermore, the intense warming over the European Continent and Caspian Sea favored the Silk Road pattern, also contributing to the southward positioning of the WPSH and the NCNEA drought. The NCNEA severe drought was therefore the joint result of Pacific SST anomalies, Arctic sea ice anomalies, and warming over the European Continent and Caspian Sea.
Developmental typologies of serious mental illness and violence: Evidence from a forensic psychiatric setting
Authors: Simpson Alexander I , Grimbos Teresa , Chan Christine , Penney Stephanie R 
Published: May 2015

Objective: To identify subgroups of forensic psychiatric patients based on the age onset of serious mental illness and offending and assess the external validity of the subgroups with theoretically based sociodemographic, clinical, legal and risk-related variables. Method: The age onset of serious mental illness and criminal contact was ascertained for a sample of 232 patients. A range of sociodemographic, clinical, legal and risk-related variables were coded to assess whether age onset subgroups differed in a manner consistent with the literature on typologies of mentally ill offenders. Results: One-quarter of the sample was classified as early starters (patients whose first offense occurred before becoming mentally ill), while two-thirds were late starters (where first offense occurred following illness onset). A small percentage (8%) of patients were deemed late late starters, defined as late starters who had experienced 10+ years of illness and were >37 years upon first arrest. A larger proportion of early starters had a substance use disorder, antisocial personality disorder and a greater number of static/historical risk factors for violence. Early starters were younger upon first arrest and had more previous criminal contacts compared to late starters and late late starters. Mental illness was found to start later in life for late late starters; this group was also more likely to have been married and to have a spouse as victim in the index offense. Conclusion: We found support for distinct subgroups of mentally ill offenders based on the age onset of illness and criminal contact. Compared to late starters, offenses committed by early starters may be motivated more frequently by antisocial lifestyle and attitudes, as well as more instrumental behaviors related to substance abuse. In addition, late late starters may represent a distinct third subgroup within late starters, characterized by relatively higher levels of functioning and social stability; future work should replicate. Findings suggest different rehabilitation needs of the subgroups.