bluuebunny/crossref_metadata_2025_split huggingface dataset:
Experiential response and intention to purchase in the cocreative consumption of music: The Nine Inch Nails experiment
Authors: Aucouturier Jean‐Julien , Fujita Marketa , Sumikura Hiroko 
Published: March 2015

AbstractCustomers allowed to cocreate products are more willing to purchase them eventually because of not only their utilitarian but also their hedonic and experiential value. Experiential responses seem especially relevant in the cocreative consumption of cultural and intangible goods, such as music. To examine how such intangible aspects of cocreation can influence a consumer's intention to purchase, we let two groups of participants rate their experience consuming music in either a traditional or cocreative way, in an experimental situation inspired by the work of American rock band Nine Inch Nails. Participants in the traditional group had to passively watch a series of music videos; participants in the cocreative group were tasked to produce a video montage using the same material. In the traditional group, purchase intention was predicted by music quality, mediated by willingness to reexperience; in the cocreative group, however, purchase intention was only predicted by the consumers' experiential response, with no mediation of either music quality or willingness to reexperience. Additionally, the overall experiential response to music was lower in the cocreative group than in the traditional group, leading to lower intention to purchase. These results suggest that cocreated value for intangible goods is predicted at least as much by the consumers' experiential response as by their evaluation of product quality. It also suggests that there is nothing systematically positive in having consumers participate in the coproduction of intangible goods and that research is needed to identify the factors predicting the perceived quality of a cocreative experience. Copyright © 2015 John Wiley & Sons, Ltd.
Coordination Chemistry of N‐Heterocyclic Nitrenium‐Based Ligands
Authors: Tulchinsky Yuri , Kozuch Sebastian , Saha Prasenjit , Mauda Assaf , Nisnevich Gennady , Botoshansky Mark , Shimon Linda J. W. , Gandelman Mark 
Published: March 2015

AbstractComprehensive studies on the coordination properties of tridentate nitrenium‐based ligands are presented. N‐heterocyclic nitrenium ions demonstrate general and versatile binding abilities to various transition metals, as exemplified by the synthesis and characterization of RhI, RhIII, Mo0, Ru0, RuII, PdII, PtII, PtIV, and AgI complexes based on these unusual ligands. Formation of nitrenium–metal bonds is unambiguously confirmed both in solution by selective 15N‐labeling experiments and in the solid state by X‐ray crystallography. The generality of N‐heterocyclic nitrenium as a ligand is also validated by a systematic DFT study of its affinity towards all second‐row transition and post‐transition metals (Y–Cd) in terms of the corresponding bond‐dissociation energies.
Redox Communication within Multinuclear Iron–Sulfur Complexes Related to Electronic Interplay in the Active Site of [FeFe]Hydrogenase
Authors: Chu Kai‐Ti , Liu Yu‐Chiao , Huang Yi‐Lan , Lee Gene‐Hsiang , Tseng Mei‐Chun , Chiang Ming‐Hsi 
Published: March 2015

AbstractThe one‐electron oxidations of a Fe2 complex lead to the formation of a persistent metal‐stabilized thiyl radical Fe2 species, mixed‐valent Fe4, and Fe8 complexes. The unpaired spin in the Fe2 radical species delocalizes over the Fe2 and the aromatic dithiolate, mostly on the terminal sulfur. The subsequent dimerization of the singly oxidized Fe2 to the Fe4 retains the partial thiyl radical character. For an analogue with less steric hindrance, the π–π stacking interaction between the dithiolato aromatic rings induces generation of the Fe8, in which process electronic structures of the species are modulated through reducing the thiyl radical to the thiolate. Electronic reorganization repeats when the Fe8 is converted to Fe4. Electronic interplay in the complexes decreases the energy gap of frontier MOs and buffers electronic impacts upon redox events. Easier accessible redox potentials and increased stability of the species are facilitated. The results demonstrate that electronic versatility of the benzenedithiolate exerts pronounced influences on electronic and coordination structure of the metal complexes.
Synthesis of Cu3Sn Alloy Nanocrystals through Sequential Reduction Induced by Gradual Increase of the Reaction Temperature
Authors: Cho Sanghun , Shin Dong‐Hun , Yin Zhenxing , Lee Chaedong , Park Si Yun , Yoo Jeeyoung , Piao Yuanzhe , Kim Youn Sang 
Published: March 2015

AbstractCu3Sn alloy nanocrystals are synthesized by sequential reduction of Cu and Sn precursors through a gradual increase of the reaction temperature. By transmission electron microscopy (TEM), energy‐dispersive X‐ray spectroscopy (EDS), UV/Vis spectroscopy, and X‐ray diffraction (XRD) analyses, the alloy formation mechanism of Cu3Sn nanocrystals has been studied. The incremental increase of the reaction temperature sequentially induces the reduction of Sn, the diffusion of Sn into the preformed Cu nanocrystals, resulting in the intermediate phase of Cu–Sn alloy nanocrystals, and then the formation of Cu3Sn alloy nanocrystals. We anticipate that the synthesis of Cu3Sn alloy nanocrystals encourages studies toward the synthesis of various alloy nanomaterials.
Well‐Defined Palladium Nanoparticles Supported on Siliceous Mesocellular Foam as Heterogeneous Catalysts for the Oxidation of Water
Authors: Verho Oscar , Åkermark Torbjörn , Johnston Eric V. , Gustafson Karl P. J. , Tai Cheuk‐W. , Svengren Henrik , Kärkäs Markus D. , Bäckvall Jan‐E. , Åkermark Björn 
Published: March 2015

AbstractHerein, we describe the use of Pd nanoparticles immobilized on an amino‐functionalized siliceous mesocellular foam for the catalytic oxidation of H2O. The Pd nanocatalyst proved to be capable of mediating the four‐electron oxidation of H2O to O2, both chemically and photochemically. The Pd nanocatalyst is easy to prepare and shows high chemical stability, low leaching, and recyclability. Together with its promising catalytic activity, these features make the Pd nanocatalyst of potential interest for future sustainable solar‐fuel production.
Synthesis of Elusive Chloropnictenium Ions
Authors: Hering‐Junghans Christian , Thomas Max , Villinger Alexander , Schulz Axel 
Published: March 2015

AbstractThis work describes the synthesis and full characterization of elusive chloropnictenium ion salts of the type [RAr*N(SiMe)ECl][A] (RAr*=2,6‐(CHPh2)‐4‐R‐C6H2, R=Me, tBu; E=Sb, Bi; A−=GaCl4, Al(OCH(CF3)2)4). In these species the cation is significantly stabilized by weak arene interactions to flanking phenyl groups of the RAr* moiety. In this context the bonding situation has been studied by computational means and the reactivity towards the Lewis base 4‐dimethylaminopyridine (dmap) was investigated.
Acceleration of Long‐Range Photoinduced Electron Transfer through DNA by Hydroxyquinolines as Artificial Base Pairs
Authors: Bätzner Effi , Liang Yu , Schweigert Caroline , Unterreiner Andreas‐Neil , Wagenknecht Hans‐Achim 
Published: March 2015

AbstractThe C‐nucleoside based on the hydroxyquinoline ligand (Hq) is complementary to itself and forms stable Hq–Hq pairs in double‐stranded DNA. These artificial Hq–Hq pairs may serve as artificial electron carriers for long‐range photoinduced electron transfer in DNA, as elucidated by a combination of gel electrophoretic analysis of irradiated samples and time‐resolved transient absorption spectroscopy. For this study, the Hq–Hq pair was combined with a DNA‐based donor–acceptor system consisting of 6‐N,N‐dimethylaminopyrene conjugated to 2′‐deoxyuridine as photoinducible electron donor, and methyl viologen attached to the 2′‐position of uridine as electron acceptor. The Hq radical anion was identified in the time‐resolved measurements and strand cleavage products support its role as an intermediate charge carrier. Hence, the Hq–Hq pair significantly enhances the electron hopping capability of DNA compared to natural DNA bases over long distances while keeping the self‐assembly properties as the most attractive feature of DNA as a supramolecular architecture.
Sympathetic Preganglionic Neurons: Properties and Inputs
Authors: Deuchars Susan A. , K. Lall Varinder 
Published: March 2015

ABSTRACTThe sympathetic nervous system comprises one half of the autonomic nervous system and participates in maintaining homeostasis and enabling organisms to respond in an appropriate manner to perturbations in their environment, either internal or external. The sympathetic preganglionic neurons (SPNs) lie within the spinal cord and their axons traverse the ventral horn to exit in ventral roots where they form synapses onto postganglionic neurons. Thus, these neurons are the last point at which the central nervous system can exert an effect to enable changes in sympathetic outflow. This review considers the degree of complexity of sympathetic control occurring at the level of the spinal cord. The morphology and targets of SPNs illustrate the diversity within this group, as do their diverse intrinsic properties which reveal some functional significance of these properties. SPNs show high degrees of coupled activity, mediated through gap junctions, that enables rapid and coordinated responses; these gap junctions contribute to the rhythmic activity so critical to sympathetic outflow. The main inputs onto SPNs are considered; these comprise afferent, descending, and interneuronal influences that themselves enable functionally appropriate changes in SPN activity. The complexity of inputs is further demonstrated by the plethora of receptors that mediate the different responses in SPNs; their origins and effects are plentiful and diverse. Together these different inputs and the intrinsic and coupled activity of SPNs result in the rhythmic nature of sympathetic outflow from the spinal cord, which has a variety of frequencies that can be altered in different conditions. © 2015 American Physiological Society.Compr Physiol5:829‐869, 2015.
Endothelial Cell Regulation of Pulmonary Vascular Tone, Inflammation, and Coagulation
Authors: Goldenberg Neil M. , Kuebler Wolfgang M. 
Published: March 2015

ABSTRACTThe pulmonary endothelium represents a heterogeneous cell monolayer covering the luminal surface of the entire lung vasculature. As such, this cell layer lies at a critical interface between the blood, airways, and lung parenchyma, and must act as a selective barrier between these diverse compartments. Lung endothelial cells are able to produce and secrete mediators, display surface receptor, and cellular adhesion molecules, and metabolize circulating hormones to influence vasomotor tone, both local and systemic inflammation, and coagulation functions. In this review, we will explore the role of the pulmonary endothelium in each of these systems, highlighting key regulatory functions of the pulmonary endothelial cell, as well as novel aspects of the pulmonary endothelium in contrast to the systemic cell type. The interactions between pulmonary endothelial cells and both leukocytes and platelets will be discussed in detail, and wherever possible, elements of endothelial control over physiological and pathophysiological processes will be examined. © 2015 American Physiological Society.Compr Physiol5:531‐559, 2015.
Fetal Programming and Cardiovascular Pathology
Authors: Alexander Barbara T. , Dasinger John Henry , Intapad Suttira 
Published: March 2015

ABSTRACTLow birth weight serves as a crude proxy for impaired growth during fetal life and indicates a failure for the fetus to achieve its full growth potential. Low birth weight can occur in response to numerous etiologies that include complications during pregnancy, poor prenatal care, parental smoking, maternal alcohol consumption, or stress. Numerous epidemiological and experimental studies demonstrate that birth weight is inversely associated with blood pressure and coronary heart disease. Sex and age impact the developmental programming of hypertension. In addition, impaired growth during fetal life also programs enhanced vulnerability to a secondary insult. Macrosomia, which occurs in response to maternal obesity, diabetes, and excessive weight gain during gestation, is also associated with increased cardiovascular risk. Yet, the exact mechanisms that permanently change the structure, physiology, and endocrine health of an individual across their lifespan following altered growth during fetal life are not entirely clear. Transmission of increased risk from one generation to the next in the absence of an additional prenatal insult indicates an important role for epigenetic processes. Experimental studies also indicate that the sympathetic nervous system, the renin angiotensin system, increased production of oxidative stress, and increased endothelin play an important role in the developmental programming of blood pressure in later life. Thus, this review will highlight how adverse influences during fetal life and early development program an increased risk for cardiovascular disease including high blood pressure and provide an overview of the underlying mechanisms that contribute to the fetal origins of cardiovascular pathology. © 2015 American Physiological Society.Compr Physiol5:997‐1025, 2015.
Thioredoxin Superfamily and Its Effects on Cardiac Physiology and Pathology
Authors: Yoshioka Jun 
Published: March 2015

ABSTRACTA precise control of oxidation/reduction of protein thiols is essential for intact cardiac physiology. Irreversible oxidative modifications have been proposed to play a role in the pathogenesis of cardiovascular diseases. An imbalance of redox homeostasis with diminution of antioxidant capacities predisposes the heart to oxidant injury. There is growing interest in endoplasmic reticulum (ER) stress in the cardiovascular field, since perturbation of redox homeostasis in the ER is sufficient to cause ER stress. Because a number of human diseases are related to altered redox homeostasis and defects in protein folding, many research efforts have been devoted in recent years to understanding the structure and enzymatic properties of the thioredoxin superfamily. The thioredoxin superfamily has been well documented as thiol oxidoreductases to exert a role in various cell signaling pathways. The redox properties of the thioredoxin motif account for the different functions of several members of the thioredoxin superfamily. While thioredoxin and glutaredoxin primarily act as antioxidants by reducing protein disulfides and mixed disulfide, another member of the superfamily, protein disulfide isomerase (PDI), can act as an oxidant by forming intrachain disulfide bonds that contribute to proper protein folding. Increasing evidence suggests a pivotal role of PDI in the survival pathway that promotes cardiomyocyte survival and leads to more favorable cardiac remodeling. Thus, the thiol redox state is important for cellular redox signaling and survival pathway in the heart. This review summarizes the key features of major members of the thioredoxin superfamily directly involved in cardiac physiology and pathology. © 2015 American Physiological Society.Compr Physiol5:513‐530, 2015.
Myocardial Tissue Caveolae
Authors: Sanon Vani P. , Sawaki Daigo , Mjaatvedt Corey H. , Jourdan‐Le Saux Claude 
Published: March 2015

ABSTRACT

Caveolae and their coat proteins, caveolins (Cav), are cave‐like invaginations found in the plasma membrane of a variety of cells. These unique vesicles and their coat proteins, Cavs, have diverse effects on endothelial function, nitric oxide synthesis regulation, signal transduction, cholesterol metabolism, and apoptosis. Animal studies in Cav knockout mice demonstrate the vital role of these structural proteins on endothelial and vascular function. Genetic studies have proposed that beside neoplasia, Cavs may play a role in the development of atherosclerosis, cardiomyopathy, long QT syndrome, pulmonary fibrosis, and muscular dystrophy. The role of Cav expression in atherosclerotic disease is poorly understood and remains controversial. Interestingly, there is emerging evidence between low Cav‐1 levels and the vulnerable plaque, which could potentially identify Cav‐1 as a novel plaque biomarker. Cavs, through intricate biochemical pathways involving endothelial nitric oxide synthase and mitogen‐activated protein kinase, are known to affect the cardiovascular system at multiple levels. In the present review, we aim to highlight the nature and types of caveolae, caveolar signaling mechanisms and regulation, and the pathophysiology of Cavs as it pertains to the cardiovascular system. Ongoing research is needed to clarify the diagnostic and prognostic role of these novel proteins and to determine how the effects of Cavs can translate into clinical medicine. © 2015 American Physiological Society.
Compr Physiol
5:871‐886, 2015.
Nitric Oxide and the Cardiovascular System
Authors: Bohlen Harold Glenn 
Published: March 2015

ABSTRACTNitric oxide (NO) generated by endothelial cells to relax vascular smooth muscle is one of the most intensely studied molecules in the past 25 years. Much of what is known about NO regulation of NO is based on blockade of its generation and analysis of changes in vascular regulation. This approach has been useful to demonstrate the importance of NO in large scale forms of regulation but provides less information on the nuances of NO regulation. However, there is a growing body of studies on multiple types ofin vivomeasurement of NO in normal and pathological conditions. This discussion will focus onin vivostudies and how they are reshaping the understanding of NO's role in vascular resistance regulation and the pathologies of hypertension and diabetes mellitus. The role of microelectrode measurements in the measurement of [NO] will be considered because much of the controversy about what NO does and at what concentration depends upon the measurement methodology. For those studies where the technology has been tested and found to be well founded, the concept evolving is that the stresses imposed on the vasculature in the form of flow‐mediated stimulation, chemicals within the tissue, and oxygen tension can cause rapid and large changes in the NO concentration to affect vascular regulation. All these functions are compromised in both animal and human forms of hypertension and diabetes mellitus due to altered regulation of endothelial cells and formation of oxidants that both damage endothelial cells and change the regulation of endothelial nitric oxide synthase. © 2015 American Physiological Society.Compr Physiol5:803‐828, 2015.
Low‐Cost Synthesis of Bimodal Mesoporous Silica‐Based Materials by Pseudomorphic Transformation
Authors: Morales José Manuel , Moragues Alaina , El Haskouri Jamal , Guillem Carmen , Latorre Julio , Murcia‐Mascarós Sonia , Beltrán Aurelio , Beltrán Daniel , Amorós Pedro 
Published: March 2015

AbstractNanoparticulate bimodal porous silica‐based materials have been prepared through a surfactant‐assisted procedure by using a simple template and starting from inexpensive sodium silicate as silicon source. Different procedural variables, such as pH or the nature and concentration of the surfactant, have been explored to optimize the preparative protocol, which allows, in turn, improved understanding of the formation process. The final bulk materials (called UVM‐10 or M‐UVM‐10) are formed by pseudomorphic transformation of fresh silica‐based xerogels under mild basic conditions. The UVM‐10 architecture is constructed from small mesoporous nanoparticles, the aggregation of which generates a disordered secondary 3 D pore system (large‐meso/macropores) defined by interparticle voids. Modulation of the intraparticle mesopore size is achieved by using surfactants with variable tail lengths, while maintaining the same head group. Textural porosity has been handled independently by hydrothermally modifying the particle size of the reactive silica‐based xerogel. By simply adding metal alkoxides to the initial reaction mixture, the preparative protocol allows for functionalizing the silica walls by incorporating relatively high proportions of homogeneously dispersed heteroelements, such as Al and Ti.
Controlling Localization and Excretion of Nanoparticles by Click Modification of the Surface Chemical Structures inside Living Cells
Authors: Ito Takeo , Nakamura Takuma , Kusaka Eriko , Kurihara Ryohsuke , Tanabe Kazuhito 
Published: March 2015

AbstractSurface modification of silica nanoparticles (SiNPs) inside living cells was conducted by using the copper‐free bioorthogonal click reaction to evaluate the effects of surface chemical structures on dynamic behavior and excretion of SiNPs. The results demonstrated the spatial translocation of intracellular SiNPs to the plasma membrane upon surface modification in situ with phospholipids. Moreover, the extent and kinetics of excretion of the SiNPs from inside the cell were enhanced by modification.
Binge eating disorder and medical comorbidities in bariatric surgery candidates
Authors: Mitchell James E. , King Wendy C. , Pories Walter , Wolfe Bruce , Flum David R. , Spaniolas Konstatinos , Bessler Mark , Devlin Michael , Marcus Marsha D. , Kalarchian Melissa , Engel Scott , Khandelwal Saurobh , Yanovski Susan 
Published: March 2015

ABSTRACTObjective To determine whether binge eating disorder (BED) status is associated with medical comorbidities in obese adults scheduled for bariatric surgery.Method The study utilized Longitudinal Assessment of Bariatric Surgery‐2 data obtained from six clinical centers around the United States. This is a well‐phenotyped cohort of individuals who were evaluated within 30 days before their scheduled surgery using standardized protocols. In the cohort, 350 participants were classified as having BED and 1,875 as not having BED (non‐BED). Multivariable logistic regression was used to determine whether BED status was independently related to medical comorbidities. As an exploratory analysis, significance was based on nominal p‐values (p < .05). Holm's‐adjusted p‐values were also reported.Results After adjusting for age, sex, education, and body mass index, BED status was found to be independently associated with four of the 15 comorbidities (i.e., impaired glucose levels (odds ratio [OR] = 1.45 (95% confidence interval [CI]: 1.12–1.87)), high triglycerides (OR = 1.28 (95% CI: 1.002–1.63)), and urinary incontinence (OR = 1.30 (95% CI: 1.02–1.66)), all being more common among the BED sample, and severe walking limitations being less common in the BED sample (OR = 0.53 (95% CI: 0.29–0.96)). With further adjustment for psychiatric/emotional health indicators, BED status was independently associated with three comorbidities (impaired glucose levels (OR = 1.36 (95% CI: 1.04–1.79)), cardiovascular disease (OR = 0.50 (95% CI: 0.30–0.86)), and severe walking limitations (OR = 0.38 (95% CI: 0.19–0.77)). However, Holm's‐adjusted p‐values for all variables were greater than .05.Discussion The results suggest the possibility of a contribution of BED to risk of specific medical comorbidities in severely obese adults. © 2015 Wiley Periodicals, Inc. (Int J Eat Disord 2015; 48:471–476)