bluuebunny/crossref_metadata_2025_split huggingface dataset:
Day‐case artificial urinary sphincter for post‐prostatectomy incontinence: A comparative pilot study
Authors: Kapriniotis Konstantinos , Loufopoulos Ioannis , Nobrega Richard , Noah Anthony , Gresty Helena , Greenwell Tamsin , Ockrim Jeremy 
Published: July 2024

AbstractObjectivesImplantation of an artificial urinary sphincter (AUS) to treat post‐prostatectomy incontinence (PPI) has been traditionally offered with an overnight hospital stay. The aim of this prospective, comparative pilot study was to assess the feasibility and outcomes of the AUS procedure in a day‐case setting.Patients and methodsWe included consecutive patients having primary or redo AUS surgery over an 18‐month period. We excluded patients with previous urethral erosion of AUS, urethroplasty or high anaesthetic risk. All patients were offered day‐case surgery. Patients who declined or could not have day‐case surgery for logistical reasons had standard care with overnight stay and formed the control group for the study. Primary outcome was the proportion of successful same day‐discharges in the day‐case group. We also compared baseline characteristics, complications and continence at 1 year post surgery.ResultsTwelve patients consented for day‐case procedure, and 13 patients had standard overnight care. Mean age was 69.5 years (range 58–79). Twenty‐one patients (84%) had primary AUS, whereas 4 (16%) had a redo procedure. There were no significant differences between the groups in baseline demographics. Median number of pads/24 h was 5 in the day‐case group and 4 in the overnight group. Eight of 12 patients (66.7%) in the day‐case group were successfully discharged on the same day. Failed discharges were due to anaesthetic recovery (n = 2), high post‐void residuals that resolved spontaneously (n = 1) and intraoperative superficial urethral injury (n = 1). All patients in the day‐case group and all but one in the standard of care group were socially continent (0–1 pads) at 1 year post procedure.ConclusionDay‐case catheter‐free discharge of AUS patients is feasible and safe in selected patients with comparable continence outcomes and complication rates to those with standard overnight stays.
„History is touchy“ Die History‐of‐Programming‐Languages‐Konferenz, 1978
Authors: Mittlmeier Amelie 
Published: July 2024

AbstractLess than twenty years after computer science was able to establish itself as an academic discipline, a group of US computer scientists organized a conference on the history of programming languages. The conference is distinguished from other self‐historicization projects by the organizer's claim to present an “accurate” account of their own discipline's history. However, the actors encountered challenges in terms of how to present their own history “objectively.” How to deal with incomplete memories? How to avoid putting others in a bad light? There was far from agreement on these points and heated discussions ensued. Strategies had to be developed and compromises made to make the project a reality. The conference was intended to contribute to the history of computer science and the organizers sought exchange with professional historians. However, the project met with little interest among them. Rather, the discussion between the computer scientists and the historians shows how the history of science also struggled with questions of how to deal suitably with the past. In this respect, the Computer Scientists’ Conference not only illuminates the history of computer science, but also offers a new perspective on the history of the history of science.
Intramuscular administration of fractalkine modulates mitochondrial properties and promotes fast glycolytic phenotype
Authors: Swalsingh Gourabamani , Pani Punyadhara , Senapati Unmod , Sahu Bijayashree , Pani Sunil , Pati Benudhara , Rout Subhasmita , Bal Naresh C. 
Published: July 2024

AbstractA newly categorized myokine called fractalkine (CX3CL1) has been associated with divergent conditions such as obesity, tissue inflammation, and exercise. CX3CL1 works through specific membrane‐bound receptors (CX3CR1) found in various tissues including skeletal muscles. Studies indicate CX3CL1 induces muscles to uptake energy substrates thereby improving glucose utilization and countering diabetes. Here, we tested if the administration of purified CX3CL1 directly into mice skeletal muscles affects its histoarchitecture, mitochondrial activity, and expression of metabolic proteins. We analyzed four muscles: two upper‐limb (quadriceps, hamstrings) and two lower‐limb (tibialis anterior, gastrocnemius), contralateral leg muscles were taken as controls. The effects of CX3CL1 treatment on histoarchitecture, mitochondrial activity, and expression of metabolic proteins in muscles were characterized. We used histochemical staining succinate dehydrogenase (SDH)/cytochrome c oxidase (COX), myosin ATPase, alkaline phosphatase (ALP) to evaluate the mitochondrial activity, fiber types, and vascularization in the muscles, respectively. Western blotting was used to evaluate the expression of proteins associated with mitochondrial metabolism (OXPHOS), glycolysis, and vascularization. Overall, this study indicates CX3CL1 primarily modulates mitochondrial metabolism and shifts substrate preference toward glucose in the skeletal muscle. Evidence also supports that CX3CL1 stimulates the relative composition of fast fiber types, influencing selection of energy substrates in the skeletal muscle.
Just passing through: Deploying aquaporins in microbial cell factories
Authors: Jenkins Sánchez Liam Richard , Sips Lobke Maria , Van Bogaert Inge Noëlle Adriënne 
Published: July 2024

AbstractAs microbial membranes are naturally impermeable to even the smallest biomolecules, transporter proteins are physiologically essential for normal cell functioning. This makes transporters a key target area for engineering enhanced cell factories. As part of the wider cellular transportome, aquaporins (AQPs) are responsible for transporting small polar solutes, encompassing many compounds which are of great interest for industrial biotechnology, including cell feedstocks, numerous commercially relevant polyols and even weak organic acids. In this review, examples of cell factory engineering by targeting AQPs are presented. These AQP modifications aid in redirecting carbon fluxes and boosting bioconversions either by enhanced feedstock uptake, improved intermediate retention, increasing product export into the media or superior cell viability against stressors with applications in both bacterial and yeast production platforms. Additionally, the future potential for AQP deployment and targeting is discussed, showcasing hurdles and considerations of this strategy as well as recent advances and future directions in the field. By leveraging the natural diversity of AQPs and breakthroughs in channel protein engineering, these transporters are poised to be promising tools capable of enhancing a wide variety of biotechnological processes.
A Review of Electrospun Carbon‐Based Nanofibers Materials used in Lithium‐Sulfur Batteries
Authors: Wei Chengbiao , Shao Xiaodong , Lin Feng , Liu Xiaoyan , Ding Wei , Wang Guoxu , Liu Hao , Gan Ruihui 
Published: July 2024

AbstractCommercial lithium‐ion batteries are gradually approaching their theoretical specific energy, which cannot meet the fast‐growing energy storage demands. Lithium‐sulfur (Li−S) batteries are anticipated to supersede lithium‐ion batteries as the next‐generation energy storage system owing to their high atheoretical specific capacity (1675 mAh g−1) and energy density (2600 Wh kg−1). Nonetheless, Li−S batteries encounter several challenges, including the inadequate conductivity of sulfur and lithium sulfide, sulfur's volume expansion, and the shuttle effect of lithium polysulfides, all of which significantly impact the practical utilization of Li−S batteries. Electrospun carbon‐based nanofibers can simultaneously resolve these issues with their economical preparation, distinctive nanostructure, and exceptional flexibility. This review presents the most recent research findings on electrospun carbon‐based nanofibers materials serving as sulfur hosts and interlayer components in Li−S batteries. We analyzed the impact of the material's structural design on the performance of Li−S batteries and the relative underlying mechanism. Finally, the current challenges and issues faced by carbon‐based nanofibers composites in the application of Li−S batteries are summarized, and the future development trajectory are outlined.
Theoretical Insight into Complexation Between Cyclocarbons and C60 Fullerene
Authors: Liu Zeyu , Lu Tian 
Published: July 2024

AbstractThis work conducts a comprehensive theoretical study on the non‐covalent complexation between cyclocarbons and C60 fullerene for the first time. The binding energy between cyclocarbons and C60 fullerene is significantly stronger than that between two C18 or two C60 fullerenes, indicating a particularly strong affinity. The cyclocarbons and C60 fullerene can spontaneously assemble into complexes in the gas phase at room temperature, and the hydrophobic effect caused by the solvent environment can promote this binding. The binding strength with C60 fullerene increases almost linearly with the increase of cyclocarbon size, and the C34@C60 dimer exhibits a perfect nano‐Saturn structure. As the ring size increases, the angle between the two cyclocarbons of the 2 : 1 trimers formed by cyclocarbons and C60 fullerene gradually decreases. In C60@2 C34 trimer, the fullerene is symmetrically surrounded by two cyclocarbons. The results on the trimers formed by cyclocarbon and C60 fullerenes in a 1 : 2 ratio showed when the cyclocarbon sandwiched between two fullerenes is not quite large, the trimers exhibit an ideal dumbbell‐like structure, and the presence of the first fullerene has a significant synergistic effect on the binding of the second one. The cyclocarbon greatly promotes the dimerization of fullerenes, which acted as a “molecular glue”.
Helix‐to‐Disc Conversion of Thia[6]helicenes into Coronenes Facilitated by Sulfur Oxidation and Fluorination
Authors: Seino Kaito , Okano Tsubasa , Oya Koki , Katagiri Hiroshi , Murase Takashi 
Published: July 2024

AbstractHelicenes, with their unique helical structures, have long captured the interest of synthetic chemists, not only as end products, but also as versatile platforms for further chemical transformations. However, transforming [6]helicene into planar coronene typically requires harsh conditions and poses significant challenges. Herein, we demonstrate that replacing the terminal benzene ring of [6]helicene with a thiophene ring enables its photochemical transformation into coronene. Sulfur oxidation of the thiophene ring enables the corresponding thermal transformation, and the terminal tetrafluorination of the opposite benzene ring further accelerates this process, yielding 1,2‐difluorocoronene, as confirmed by X‐ray crystallography. The transformation begins with an intramolecular Diels–Alder reaction, whose activation energy is significantly lowered by these structural changes. Our findings underscore the utility of strategic modifications such as sulfur oxidation and fluorination in promoting this “helix‐to‐disc” conversion and opening new avenues for synthesizing functional polycyclic aromatics.
Secure paths based trustworthy fault‐tolerant routing in data center networks
Authors: Liu Kaiyun , Fan Weibei , Xiao Fu , Mao Haolin , Huang Huipeng , Zhao Yizhou 
Published: July 2024

SummaryWith the continuous expansion scale of data center networks (DCNs), the probability of network failures becomes high. Trustworthy fault‐tolerant routing is extremely significant for reliable communication in data centers. In this article, we tackle the challenge by proposing a novel fault‐tolerant routing scheme for a torus‐based DCN. First, we present a multipath information transmission model based on the trust degree of reachable paths and propose a novel Hamiltonian odd–even turning model without deadlock. Second, we design an efficient deadlock‐free fault‐routing algorithm by constructing the longest fault‐free path between any two fault‐free nodes in DCN. Extensive simulation results show that the proposed fault‐tolerant routing outperforms the previous algorithms. Compared with the most advanced fault‐tolerant routing algorithms, the proposed algorithm has a 21.5% to 25.3% increase in throughput and packet arrival rate. Moreover, it can reduce the average delay of 18.6% and the maximum delay of 23.7% in the network respectively.
Chemistry of Antimony in Radiopharmaceutical Development: Unlocking the Theranostic Potential of Sb Isotopes
Authors: Grundmane Aivija , Radchenko Valery , Ramogida Caterina F. 
Published: July 2024

AbstractAntimony‐119 (119Sb) holds promise for radiopharmaceutical therapy (RPT), emitting short‐range Auger and conversion electrons that can deliver cytotoxic radiation on a cellular level. While it has high promise theoretically, experimental validation is necessary for 119Sb in vivo applications. Current 119Sb production and separation methods face robustness and compatibility challenges in radiopharmaceutical synthesis. Limited progress in chelator development hampers targeted experiments with 119Sb. This review compiles literature on the toxicological, biodistribution and redox properties of Sb, along with existing Sb complexes, evaluating their suitability for radiopharmaceuticals. Sb(III) is suggested as the preferred oxidation state for radiopharmaceutical elaboration due to its stability in vivo and lack of skeletal uptake. While Sb complexes with both hard and soft donor atoms can be achieved, Sb thiol complexes offer enhanced stability and compatibility with the desired Sb(III) oxidation state. For 119Sb to find application in RPT, scientists need to make discoveries and advancements in the areas of isotope production, and radiometal chelation. This review aims to guide future research towards harnessing the therapeutic potential of 119Sb in RPT.
A Photoinduced Annulation Strategy Towards a Polycyclic Heteroaromatic Chromophore: Scope, Mechanism, Properties and Applications
Authors: Labro Marine , Pollien Audrey , Mosser Maëlle , Pitrat Delphine , Mulatier Jean‐Christophe , Seinfeld Mathilde , Bahers Tangui Le , Baguenard Bruno , Guy Stéphan , Monnereau Cyrille , Guy Laure 
Published: July 2024

AbstractThis article reports a detailed mechanistic and kinetic study of an unusual photoreaction leading to the (diazonia)tetrabenzonaphthacene skeleton. The photo‐triggered double intramolecular nucleophilic aromatic substitution (SNAr*) has been investigated by varying the leaving groups. Photoreaction quantum yields have been determined and mechanistic insights have been supported by theoretical calculations using DFT and TD‐DFT methods. Additionally, we show that this light‐triggered formed diazonia constitutes a potent photosentitizer with a singlet oxygen generation quantum yield of 0.55, both in organic solvents and in water, which is an extremely relevant value in view of PDT applications or use as an oxidation photocatalyst in aqueous media. Once again, the experimental observations were supported by TD‐DFT calculations showing a large density of triplet states below the S1 excited state along with large spin‐orbit couplings. The reaction is not restricted to solutions but can also occur in solid PDMS matrices thus allowing for photochemical encoding of information that will progressively vanish upon prolonged UV‐exposure.
Mechanical strength of stock and custom abutments as original and aftermarket components after thermomechanical aging
Authors: Pol Christiaan W. P. , Cune Marco S. , Raghoebar Gerry M. , Naves Lucas Z. , Meijer Henny J. A. 
Published: July 2024

AbstractObjectivesThe study aimed to assess the impact on the mechanical strength and failure patterns of implant‐abutment complexes of choosing different abutment types, designs and manufacturers, aiding in selecting the optimal restorative solution. Stock and custom abutments from original and aftermarket suppliers were subjected to thermomechanical aging.Material and MethodsStock and custom abutments from the implant manufacturer (original) and a aftermarket supplier (nonoriginal) were connected to identical implants with internal connection. Custom abutments were designed in a typical molar and premolar design, manufactured using the workflow from the respective suppliers. A total of 90 implants (4 mm diameter, 3.4 mm platform, 13 mm length) equally divided across 6 groups (three designs, two manufacturers) underwent thermo‐mechanical aging according to three different regimes, simulating five (n = 30) or 10 years (n = 30) of clinical function, or unaged control (n = 30). Subsequently, all samples were tested to failure.ResultsDuring aging, no failures occurred. The mean strength at failure was 1009N ± 171, showing significant differences between original and nonoriginal abutments overall (−230N ± 27.1, p < .001), and within each abutment type (p = .000), favoring original abutments. Aging did not significantly affect the failure load, while the type of abutment and manufacturer did, favoring original and custom‐designed abutments. The most common failure was implant bending or deformation, significantly differing between original and nonoriginal abutments and screws. All failure tests resulted in clinically unsalvageable implants and abutments.ConclusionsWithin the limitations of this study, original abutments exhibited a higher mechanical strength compared to the nonoriginal alternative, regardless of the amount of simulated clinical use. Similarly, custom abutments showed higher mechanical strength compared to stock abutments. However, mechanical strength in all abutments tested was higher than average chewing forces reported in literature, thus components tested in this study can be expected to perform equally well in clinical situations without excessive force.
Structural Regulation of NiFe LDH Under Spontaneous Corrosion to Enhance the Oxygen Evolution Properties
Authors: Ma Yingjun , Liu Hangning , Wang Lin , Sun Changhui , Gong Liangyu , Wang Jie , Zhang Xiaogang 
Published: July 2024

AbstractElectrochemical water splitting holds promise for sustainable hydrogen production but restricted by the sluggish reaction kinetics at the anodic oxygen evolution. Herein, we present a room‐temperature spontaneous corrosion strategy to convert inexpensive iron (Fe) on iron foam substrates into highly active and stable self‐supporting nickel iron layered hydroxide (NiFe LDH) catalysts. The corrosion evolution mechanisms are elucidated combining ex‐situ scanning electron microscopy (SEM) and X‐ray photo electron spectroscopy (XPS) techniques, demonstrating precise control over the concentration of Ni2+ and reaction time to achieve controllable micro‐structures of NiFe LDH. Taking advantage of the self‐supporting morphology and hierarchical micro‐/nano‐ structure, the NiFe LDH with optimized Ni2+ concentration and reaction time exhibits significant small overpotentials of 160 mV and 200 mV for the OER at current densities of 10 mA cm−2 and 100 mA cm−2 respectively, showcasing excellent OER activities. Furthermore, this catalyst demonstrates superior reaction kinetics, high electrochemical stability, and excellent integral water splitting performance when coupled with a commercial Pt/C cathode. The energy‐efficient, cost‐effective, and scalable spontaneous corrosion strategy opens new avenues for the development of high‐electrochemical‐interface catalysts.
Combinatorial Separation of Cd and Te from CdTe via Chemical Vapour Transport with Sulfur and Air/Methane Treatment for the Recovery of Critical Resources from Thin Film Solar Cells
Authors: Bemfert Lucas H. , Burkhart Julian , Sedykh Alexander E. , Richter Sophie , Mitura Eliane L. , Maxeiner Moritz , Sextl Gerhard , Müller‐Buschbaum Klaus 
Published: July 2024

AbstractElemental Te and Cd are successfully recovered from CdTe via a combinatorial process involving chemical vapor transport (CVT) using sulfur as transport agent giving elemental Te being deposited. Separation is successfully enabled by the first process for CVT of Te starting with CdTe. Cd is subsequently recovered by an oxidation of the formed CdS to CdO followed by reduction to Cd metal with natural gas, in which Cd can also be separated via the gas phase. Hereby, the process addresses the main critical elements of the active material in thin film CdTe solar cells regarding both, scarcity and toxicity. Both, closed and open systems were investigated displaying more or less thermodynamic control of the system. Transport rates were determined for the closed system as well as for an open system working with sulfur vapour at moderate temperatures below and close to the boiling point of sulfur. Excellent purity of tellurium was achieved already by the initial transport, leading to low Cd2+ concentrations in the obtained Te being below the quantification limit of microwave plasma‐atomic emission spectroscopy (MP‐AES) (≪0.05 wt %).
Pd‐Imidate@Sba‐15: A Multifunctional Heterogeneous Catalyst for the Aqueous Room Temperature Hydrogenation of Co2 to Formic Acid
Authors: Martín Nuria , Porcar Raúl , Serrano José L. , Pérez José , Lozano Pedro , Cirujano Francisco G. , García‐Verdugo Eduardo 
Published: July 2024

AbstractThe incorporation of hydrophilic and basic sites from phosphotriazaadamantane and saccharine in a water‐soluble Pd complex and the subsequent confinement into mesoporous silica support increases the activity and stability of the palladium catalytic species for the room‐temperature aqueous hydrogenation of either bicarbonate or CO2 into formic acid. The use of low Pd loadings (<0.1 mmolPd g−1) of the well‐dispersed complex on SBA‐15 mesoporous silica allows performing the reaction under room temperature, and aqueous conditions, exhibiting TON of ca. 40–100, for the CO2 or bicarbonate hydrogenation, respectively, which is one order of magnitude higher than the homogeneous case, allowing the easy isolation and recycling of the solid catalyst.
Introducing Fe Into Cu‐Based Catalyst to Boost Electrocatalytic Hydrogenation of 5‐Hydroxymethylfurfural
Authors: Zhao Zhefei , Yu Ruopeng , Wang Siqi , Guo Lipeng , Zhang Linlin , Chen Minhao , Chen Jun , Zheng Huajun 
Published: July 2024

AbstractConverting biomass‐derived 5‐hydroxymethylfurfural (HMF) into high‐valued 2,5‐dihydroxymethylfurfural (DHMF) via electrocatalytic hydrogenation (ECH) technology has been widely regarded as one of the most economical and eco‐friendly routes. The high selectivity and activity depend on the reasonable regulation of the adsorption and activation of adsorbed hydrogen (H*) and HMF on the surface of the electrocatalyst. Herein, we report nanoflower‐like CuFe‐based electrocatalysts on copper foam (CF) substrates (CuFeOx/CF). DHMF was achieved on the optimal CuFeOx/CF with a selectivity of 93.3 % and a yield of 90.1 %. The H*, HMF and product were observed by in situ attuned total reflection Fourier transform infrared spectroscopy (ATR‐FTIR). Moreover, in situ Raman spectra discloses the reconstruction of catalyst into CuFe‐bimetal with low valence state. Density functional theory (DFT) calculations demonstrate that introducing Fe plays a role in regulating the electronic structure of Cu sites, which facilitate the generation of H* and adsorption of HMF, thus hampering the occurrence of dimerization. This study provides an innovative idea for the rational design of non‐precious bimetallic electrocatalysts for ECH to produce high‐valued chemicals.