bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sphingolipid inhibitor response gene GhMYB86 controls fiber elongation by regulating microtubule arrangement
Authors: Xu Fan , Li Guiming , He Shengyang , Zeng Zhifeng , Wang Qiaoling , Zhang Hongju , Yan Xingying , Hu Yulin , Tian Huidan , Luo Ming 
Published: July 2024

ABSTRACTAlthough the cell membrane and cytoskeleton play essential roles in cellular morphogenesis, the interaction between the membrane and cytoskeleton is poorly understood. Cotton fibers are extremely elongated single cells, which makes them an ideal model for studying cell development. Here, we used the sphingolipid biosynthesis inhibitor, fumonisin B1 (FB1), and found that it effectively suppressed the myeloblastosis (MYB) transcription factor GhMYB86, thereby negatively affecting fiber elongation. A direct target of GhMYB86 is GhTUB7, which encodes the tubulin protein, the major component of the microtubule cytoskeleton. Interestingly, both the overexpression of GhMYB86 and GhTUB7 caused an ectopic microtubule arrangement at the fiber tips, and then leading to shortened fibers. Moreover, we found that GhMBE2 interacted with GhMYB86 and that FB1 and reactive oxygen species induced its transport into the nucleus, thereby enhancing the promotion of GhTUB7 by GhMYB86. Overall, we established a GhMBE2‐GhMYB86‐GhTUB7 regulation module for fiber elongation and revealed that membrane sphingolipids affect fiber elongation by altering microtubule arrangement.
I need new friends! Changes in perceived peer drinking norms and developmental outcomes across the transition to college
Authors: Benner Aprile D. , Shen Yishan , Kloska Deborah D. 
Published: July 2024

AbstractThe current study investigated changes in proximal descriptive alcohol use norms from high school to college, social integration as a predictor of stable versus shifting peer norms, and the consequences of norm profile membership for developmental outcomes. Using data (N = 9753 12th grade students; 59% female; 80% White, 7% Black, 5% Hispanic, 5% Asian/Pacific Islander, 3% other races/ethnicities) from the Monitoring the Future panel study, we identified five distinct norm profiles—three stable profiles (high, moderate‐high, and low) and two shifting profiles (increasing, declining)—that had unique patterns of perceived friend alcohol use norms. Social integration distinguished norm profile membership, and we observed particular detriments to outcomes for those in the stable high peer norm profile.
Presenting objects for random allocation
Authors: Liu Peng , Xu Sijia 
Published: July 2024

AbstractFor random allocation, whether a desirable rule exists or not hinges on the domain of agents' preferences, whose formation is affected by how objects are presented. We hence propose a model studying how to present objects so that the induced preference domain allows for designing a good rule. Motivated by practices in reality, we model the objects as combinations of several attribute values and a presentation of objects concerns a choice of presenting attributes and a ranking of them. Agents are assumed to formulate their preferences in a lexicographic manner according to the given presentation. We show that the domain of preferences induced by a presentation allows for a strategy‐proof, efficient, and envy‐free rule if and only if the presented attributes are conditionally binary.
The electroretinography to identify biomarkers of idiopathic hypersomnia and narcolepsy type 1
Authors: Rach Héloïse , Kilic‐Huck Ulker , Geoffroy Pierre A. , Bourcier Tristan , Braun Sophie , Comtet Henri , Ruppert Elisabeth , Hugueny Laurence , Hebert Marc , Reynaud Eve , Bourgin Patrice 
Published: July 2024

SummaryHypersomnia spectrum disorders are underdiagnosed and poorly treated due to their heterogeneity and absence of biomarkers. The electroretinography has been proposed as a proxy of central dysfunction and has proved to be valuable to differentiate certain psychiatric disorders. Hypersomnolence is a shared core feature in central hypersomnia and psychiatric disorders. We therefore aimed to identify biomarkers by studying the electroretinography profile in patients with narcolepsy type 1, idiopathic hypersomnia and in controls. Cone, rod and retinal ganglion cells electrical activity were recorded with flash‐electroretinography in non‐dilated eye of 31 patients with idiopathic hypersomnia (women 84%, 26.6 ± 5.9 years), 19 patients with narcolepsy type 1 (women 63%, 36.6 ± 12.7 years) and 43 controls (women 58%, 30.6 ± 9.3 years). Reduced cone a‐wave amplitude (p = 0.039) and prolonged cone (p = 0.022) and rod b‐wave (p = 0.009) latencies were observed in patients with narcolepsy type 1 as compared with controls, while prolonged photopic negative response‐wave latency (retinal ganglion cells activity) was observed in patients with idiopathic hypersomnia as compared with controls (p = 0.033). The rod and cone b‐wave latency clearly distinguished narcolepsy type 1 from idiopathic hypersomnia and controls (area under the curve > 0.70), and the photopic negative response‐wave latency distinguished idiopathic hypersomnia and narcolepsy type 1 from controls with an area under the curve > 0.68. This first original study shows electroretinography anomalies observed in patients with hypersomnia. Narcolepsy type 1 is associated with impaired cone and rod responses, whereas idiopathic hypersomnia is associated with impaired retinal ganglion cells response, suggesting different phototransduction alterations in both hypersomnias. Although these results need to be confirmed with a larger sample size, the electroretinography may be a promising tool for clinicians to differentiate hypersomnia subtypes.
Historically marginalized groups and ideological representation in legislatures
Authors: Acquarone Iris E. , Di Landro Gonzalo 
Published: July 2024

AbstractA widespread assumption in political science research and among the public is that politicians from marginalized groups, including women, disadvantaged racial–ethnic groups, and younger adults, are more leftist than their counterparts. However, empirical evidence to substantiate this claim is generally scarce. In this letter, we analyze three decades of individual‐level elite data from Latin America and find that MPs from marginalized groups tend not to differ ideologically from MPs from dominant groups, nor is their inclusion associated with posterior changes in their party's ideology. These results challenge common misconceptions about elite ideology and contribute to bridging two lively literatures on the ideological and inclusionary transformations shaping current Western democracies.
Historical and contemporary processes driving the origin and structure of an admixed population within a contact zone between subspecies of a north temperate diadromous fish
Authors: Liu Amy , Geraldes Armando , Taylor Eric B. 
Published: July 2024

AbstractHybridization between divergent lineages can result in losses of distinct evolutionary taxa. Alternatively, hybridization can lead to increased genetic variability that may fuel local adaptation and the generation of novel traits and/or taxa. Here, we examined single‐nucleotide polymorphisms generated using genotyping‐by‐sequencing in a population of Dolly Varden char (Pisces: Salmonidae) that is highly admixed within a contact zone between two subspecies (Salvelinus malma malma, Northern Dolly Varden [NDV] and S. m. lordi, Southern Dolly Varden [SDV]) in southwestern Alaska to assess the spatial distribution of hybrids and to test hypotheses on the origin of the admixed population. Ancestry analysis revealed that this admixed population is composed of advanced generation hybrids between NDV and SDV or advanced backcrosses to SDV; no F1 hybrids were detected. Coalescent‐based demographic modelling supported the origin of this population about 55,000 years ago by secondary contact between NDV and SDV with low levels of contemporary gene flow. Ancestry in NDV and SDV varies within the watershed and ancestry in NDV was positively associated with distance upstream from the sea, contingent on habitat‐type sampled, and negatively associated with the number of migrations that individual fish made to the sea. Our results suggest that divergence between subspecies over hundreds of thousands of years may not be associated with significant reproductive isolation, but that elevated diversity owing to hybridization may have contributed to adaptive divergence in habitat use and life history.
Isolation by environment and its consequences for range shifts with global change: Landscape genomics of the invasive plant common tansy
Authors: Briscoe Runquist Ryan , Moeller David A. 
Published: July 2024

AbstractInvasive species are a growing global economic and ecological problem. However, it is not well understood how environmental factors mediate invasive range expansion. In this study, we investigated the recent and rapid range expansion of common tansy across environmental gradients in Minnesota, USA. We densely sampled individuals across the expanding range and performed reduced representation sequencing to generate a dataset of 3071 polymorphic loci for 176 individuals. We used non‐spatial and spatially explicit analyses to determine the relative influences of geographic distance and environmental variation on patterns of genomic variation. We found no evidence for isolation by distance but strong evidence for isolation by environment, indicating that environmental factors may have modulated patterns of range expansion. Land use classification and soils were particularly important variables related to population structure although they operated on different spatial scales; land use classification was related to broad‐scale patterns and soils were related to fine‐scale patterns. All analyses indicated a distinctive genetic cluster in the most recently invaded portion of the range. Individuals from the far northwestern range margin were separated from the remainder of the range by reduced migration, which was associated with environmental resistance. This portion of the range was invaded primarily in the last 15 years. Ecological niche models also indicated that this cluster was associated with the expansion of the niche. While invasion is often assumed to be primarily influenced by dispersal limitation, our results suggest that ongoing invasion and range shifts with climate change may be strongly affected by environmental heterogeneity.
A non‐contact identification method of overweight vehicles based on computer vision and deep learning
Authors: Li Daoheng , Liu Meiyu , Yang Lu , Wei Han , Guo Jie 
Published: July 2024

AbstractThe phenomenon of overweight vehicles severely threatens traffic safety and the service life of transportation infrastructure. Rapid and effective identification of overweight vehicles is of significant importance for maintaining the healthy operation of highways and bridges and ensuring the safety of people's lives and property. With the problems of high cost and low efficiency, the traditional vehicle weighing systems can only meet some of the requirements of different scenarios. The development of artificial intelligence technologies, especially deep learning, has greatly enhanced the accuracy and efficiency of computer vision. To this end, the paper proposes a method using computer vision and deep learning for the non‐contact identification of overweight vehicles. By constructing two deep learning models and combining them with the vehicle vibration model and relevant specifications, the weight and maximum allowable weight of the vehicle are obtained to make a comparison for determining overweight. Experimental verification was performed using a two‐axle vehicle as an illustrative example, and the results demonstrate that the proposed method exhibits excellent feasibility and effectiveness. It shows significant potential in real‐world scenarios, laying a research foundation for practical engineering applications. Additionally, it provides a reference for the governance and decision‐making of overweight issues for relevant authorities.
Construing the function of N‐terminal domain of D29 mycobacteriophage LysA endolysin in phage lytic efficiency and proliferation
Authors: Gangakhedkar Rutuja , Jain Vikas 
Published: July 2024

AbstractEndolysins produced by bacteriophages hydrolyze host cell wall peptidoglycan to release newly assembled virions. D29 mycobacteriophage specifically infects mycobacteria including the pathogenic Mycobacterium tuberculosis. D29 encodes LysA endolysin, which hydrolyzes mycobacterial cell wall peptidoglycan. We previously showed that LysA harbors two catalytic domains (N‐terminal domain [NTD] and lysozyme‐like domain [LD]) and a C‐terminal cell wall binding domain (CTD). While the importance of LD and CTD in mycobacteriophage biology has been examined in great detail, NTD has largely remained unexplored. Here, to address NTD's significance in D29 physiology, we generated NTD‐deficient D29 (D29∆NTD) by deleting the NTD‐coding region from D29 genome using CRISPY‐BRED. We show that D29∆NTD is viable, but has a longer latent period, and a remarkably reduced burst size and plaque size. A large number of phages were found to be trapped in the host during the D29∆NTD‐mediated cell lysis event. Such poor release of progeny phages during host cell lysis strongly suggests that NTD‐deficient LysA produced by D29∆NTD, despite having catalytically‐active LD, is unable to efficiently lyse host bacteria. We thus conclude that LysA NTD is essential for optimal release of progeny virions, thereby playing an extremely vital role in phage physiology and phage propagation in the environment.
Desire and Debt Satisfaction in Anselm of Canterbury and Hadewijch of Brabant
Authors: Landrith Robin 
Published: July 2024

Abstract“Satisfaction” is the famous epithet given to Anselm's atonement theory. Less well appreciated even in modern retrievals of Hadewijch's work is the centrality of “satisfaction” as a concept for her, being just as technical but more theologically extensive in her writing than it is in Anselm's. Despite cultural similarities, the meaning of satisfaction in their respective works differs. This article argues that the difference between the concepts of satisfaction in Anselm's Cur Deus Homo and Hadewijch's Brieven depends on the difference between the meaning of the “debt” that the satisfying act satisfies. Anselm's “satisfaction” (satisfactio) responds to the debt created by sin, while Hadewijch's “satisfaction” (ghenoeghen) responds to the debt created by love's demand—a debt not only, or even primarily, of the beloved to the lover, but of the lover to the beloved. Departing from depictions of debt in both medieval and modern theology, Hadewijch presents indebtedness per se not as a point of contrast between human beings and God. Instead, she suggests that atonement recreates human understanding to perceive the original meaning of debt, which is the debt of love that the divine persons “eternally demand and eternally render” from and for each other.
Integrating high‐throughput phenotyping and genome‐wide association studies for enhanced drought resistance and yield prediction in wheat
Authors: Zhang Zhen , Qu Yunfeng , Ma Feifei , Lv Qian , Zhu Xiaojing , Guo Guanghui , Li Mengmeng , Yang Wei , Que Beibei , Zhang Yun , He Tiantian , Qiu Xiaolong , Deng Hui , Song Jingyan , Liu Qian , Wang Baoqi , Ke Youlong , Bai Shenglong , Li Jingyao , Lv Linlin , Li Ranzhe , Wang Kai , Li Hao , Feng Hui , Huang Jinling , Yang Wanneng , Zhou Yun , Song Chun‐Peng 
Published: July 2024

Summary

Drought, especially terminal drought, severely limits wheat growth and yield. Understanding the complex mechanisms behind the drought response in wheat is essential for developing drought‐resistant varieties. This study aimed to dissect the genetic architecture and high‐yielding wheat ideotypes under terminal drought.

An automated high‐throughput phenotyping platform was used to examine 28 392 image‐based digital traits (i‐traits) under different drought conditions during the flowering stage of a natural wheat population. Of the i‐traits examined, 17 073 were identified as drought‐related. A genome‐wide association study (GWAS) identified 5320 drought‐related significant single‐nucleotide polymorphisms (SNPs) and 27 SNP clusters.

A notable hotspot region controlling wheat drought tolerance was discovered, in which TaPP2C6 was shown to be an important negative regulator of the drought response. The tapp2c6 knockout lines exhibited enhanced drought resistance without a yield penalty. A haplotype analysis revealed a favored allele of TaPP2C6 that was significantly correlated with drought resistance, affirming its potential value in wheat breeding programs.

We developed an advanced prediction model for wheat yield and drought resistance using 24 i‐traits analyzed by machine learning. In summary, this study provides comprehensive insights into the high‐yielding ideotype and an approach for the rapid breeding of drought‐resistant wheat.
Care biography: A concept analysis
Authors: Tieu Matthew , Allande‐Cussó Regina , Collier Aileen , Cochrane Tom , Pinero de Plaza Maria A. , Lawless Michael , Feo Rebecca , Perimal‐Lewis Lua , Thamm Carla , Hendriks Jeroen M. , Lee Jane , George Stacey , Laver Kate , Kitson Alison 
Published: July 2024

AbstractIn this article, we investigate how the concept of Care Biography and related concepts are understood and operationalised and describe how it can be applied to advancing our understanding and practice of holistic and person‐centred care. Walker and Avant's eight‐step concept analysis method was conducted involving multiple database searches, with potential or actual applications of Care Biography identified based on multiple discussions among all authors. Our findings demonstrate Care Biography to be a novel overarching concept derived from the conjunction of multiple other concepts and applicable across multiple care settings. Concepts related to Care Biography exist but were more narrowly defined and mainly applied in intensive care, aged care, and palliative care settings. They are associated with the themes of Meaningfulness and Existential Coping, Empathy and Understanding, Promoting Positive Relationships, Social and Cultural Contexts, and Self‐Care, which we used to inform and refine our concept analysis of Care Biography. In Conclusion, the concept of Care Biography, can provide a deeper understanding of a person and their care needs, facilitate integrated and personalised care, empower people to be in control of their care throughout their life, and help promote ethical standards of care.
‘You Just Struggle on Your Own’: Exploring Older People and Their Caregivers' Perspectives About Falls Prevention Education in Hospitals
Authors: Hill Anne‐Marie , Vaz Sharmila , Francis‐Coad Jacqueline , Flicker Leon , Morris Meg E. , Weselman Tammy 
Published: July 2024

ABSTRACTBackgroundProviding older patients with an opportunity to participate in individualised falls preventive education, has been shown to reduce hospital falls. However, few studies have explored older peoples' perspectives of hospital falls prevention education. This study aimed to explore older people and their caregivers' knowledge and awareness about hospital falls prevention, including their reflections on the education they received when hospitalised.MethodsA qualitative, exploratory study with focus groups and semistructured interviews was conducted. Participants were a purposively selected sample of community‐dwelling older people (65+ years) admitted to a hospital in the past 5 years and caregivers of older people. Data were thematically analysed using deductive and inductive approaches, and a capability–opportunity–motivation–behaviour model was applied to understand key determinants of implementing falls education for hospitalised older people.ResultsParticipants' [n = 46 (older people n = 37, age range 60–89 years), caregivers n = 9] feedback identified five themes: distress and disempowerment if the participant did have a hospital fall or nearly fell, anxiety and uncertainty about what behaviour was required while in hospital, insufficient and inconsistent falls prevention education, inadequate communication and underlying attitudes of ageism. Applying a behaviour change model suggested that older people and their caregivers did not develop falls prevention knowledge, awareness or motivation to engage in falls prevention behaviour. Older people were also provided with limited opportunities to engage in falls preventive behaviour while in hospital.ConclusionOlder people in our study received sporadic education about falls prevention during their hospital admissions which did not raise their awareness and knowledge about the risk of falls or their capability to engage in safe falls preventive behaviour. Conflicting messages may result in older people feeling confused and anxious about staying safe in hospital.
How international are public administration journals? An analysis of the persistent Anglo‐American dominance in public administration journals
Authors: Liu Jianzheng , Xu Yifei , Zhang Xinyun , Yu Wenxuan , Zhong Haotian 
Published: July 2024

AbstractThis study provides a comprehensive and up‐to‐date assessment of four dimensions (editors, editorial board members, authors, and geographical focus of research) of the internationalization of 45 major public administration journals and examines whether and how one dimension is related to the others. We find that Anglo‐American dominance is significant and persistent across all four dimensions in most public administration journals during 2011–2020, with the dimension of editors being the most pronounced, followed by the dimension of editorial board members, the authors' dimension, and the dimension of geographical focus of research. There are notable differences between journals. Further analyses show that the Anglo‐American dominance in editors has a self‐perpetuating tendency and is likely to lead to the Anglo‐American dominance in editorial board members, which is further significantly and positively associated with the Anglo‐American dominance in authors and the Anglo‐American dominance in geographical foci of research in public administration journals.
Worlds in Motion Redux? Expanding Migration Theories and Their Interconnections
Authors: Riosmena Fernando 
Published: July 2024

AbstractMigration theorizing has coalesced around sets encompassing several frameworks. Despite many contributions of these collections, contemporary migration theorizing exhibits three important shortcomings, which this paper aims to address. First, sets of theories have traditionally not explicitly and jointly addressed fundamental questions in migration, namely (i) key motivations beyond those related to “labor” (turmoil; environmental strain; family, or self‐realization factors); (ii) how important axes of social difference produce distinct motivations and mechanisms (e.g., by gender and sexuality); (iii) the (in)direct roles of the state; (iv) important spatial considerations, that is, immobility, internal versus international movement, step/onward/secondary migrations; and (v) key issues of temporality, that is, return migration, its timing, and intentionality. Engaging with classical and contemporary scholarship, I provide an updated, revised, and broadened set of frameworks and analytical lenses that better incorporate these issues. Second, the most common typology used to categorize frameworks into “initiation” and “continuation” suffers from ambiguity and imprecision. I offer a new classification, typifying mechanisms as more/less endogenous to prior migrations. Third, scholarship has advanced little in systematically examining whether/how theories relate to each other. I provide a basic taxonomy of mechanism “competition,” “coexistence,” co‐occurrence, and interrelation. I conclude by proposing a new and expanded set of frameworks and analytical lenses, reflecting on the implications of these modifications.