bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gender Commonalities and Differences in the Neural Processing of Visual Sexual Stimuli
Authors: Wehrum Sina , Klucken Tim , Kagerer Sabine , Walter Bertram , Hermann Andrea , Vaitl Dieter , Stark Rudolf 
Published: February 2013

ABSTRACT

Introduction
Few studies so far have directly compared the neural processing of visual sexual stimuli in men and women. Also, most of these studies only compared sexual with neutral stimuli, making it difficult to disentangle sexual stimulus processing from general emotional processing.

Aim
The current study aimed to explore gender commonalities and differences in neural activity associated with the processing of visual sexual stimuli in a large sample of 50 men and 50 women. In order to disentangle effects of sexual processing from those of general emotional processing, we employed sexual, neutral, positive, and negative emotional pictures.

Methods
Subjects passively viewed sexual, neutral, positive, and negative emotional pictures during a functional magnetic resonance imaging (fMRI) session. Pictures were presented in 24 blocks of five pictures each. Every block was rated immediately after its presentation with respect to valence, arousal, and sexual arousal.

Main Outcome Measures
Blood oxygen level dependent responses measured by fMRI and subjective ratings.

Results
fMRI analysis revealed a distributed network for the neural processing of sexual stimuli comprising the hypothalamus, the nucleus accumbens, as well as orbitofrontal, occipital, and parietal areas. This network could be identified (i) for both men and women, with men showing overall stronger activations than women and (ii) independent of general emotional arousal or valence effects.

Conclusion
Our data speak in favor of a common neural network associated with the processing of visual sexual stimuli in men and women. Apart from the observed gender commonalities, overall stronger responses in men were observed that might indicate stronger sexual responsivity in men
Psychological, lifestyle and social predictors of hepatitis C treatment response: a systematic review
Authors: Sublette Victoria A. , Douglas Mark W. , McCaffery Kirsten , George Jacob , Perry Kathryn Nicholson 
Published: February 2013

AbstractBackgroundTo increase cure rates for Hepatitis C, barriers to treatment adherence and completion must be identified and overcome.AimsThis study systematically reviewed evidence on the psychological, lifestyle and social determinants of achieving viral eradication with antiviral therapy.MethodsAn electronic search strategy was used to identify relevant studies that examined psychological, lifestyle and social factors related to achieving a sustained virological response (SVR).ResultsThirty‐four studies that matched our criteria were identified. Of the factors that predict response to treatment, Asian ethnicity was an independent predictor of SVR. We found an indirect relationship between diet and SVR, with non‐responders to treatment consuming more polyunsaturated fatty acids, fats and carbohydrates than those who attained SVR. The effect of alcohol consumption relied on the amount consumed; fewer than 30 grams daily had no effect on SVR, whereas >70 grams daily had an adverse impact on a patient's ability to achieve SVR, with termination rates up to 44% in those who drank >2 drinks a day. Patients with psychiatric illnesses had comparable SVR rates to controls if they continued psychological therapy (average 42%), although discontinuation rates were high with 11 studies reporting rates from 14 to 48%.ConclusionsThere are major gaps in current knowledge of the impact of variables such as diet, exercise, attitudes and coping skills on cure rates in chronic Hepatitis C. Those who drink limited amounts of alcohol or have psychiatric disorders should be offered treatment for their disease, with adjunctive education and support to improve treatment completion.
Homogeneous distribution of Fe isotopes in the early solar nebula
Authors: Wang Kun , Moynier Frédéric , Barrat Jean‐Alix , Zanda Brigitte , Paniello Randal C. , Savage Paul S. 
Published: February 2013

AbstractTo examine the iron (Fe) isotopic heterogeneities ofCIand ordinary chondrites, we have analyzed several large chips (approximately 1 g) from threeCIchondrites and three ordinary chondrites (LL5, L5, and H5). The Fe isotope compositions of five different samples of Orgueil, one from Ivuna and one from Alais (CIchondrites), are highly homogeneous. This new dataset provides a δ56Fe average of 0.02 ± 0.04‰ (2SE,n = 7), which represents the best available value for the Fe isotopic composition ofCIchondrites and probably the best estimate of the bulk solar system. We conclude that the homogeneity ofCIchondrites reflects the initial Fe isotopic homogeneity of the well‐mixed solar nebula. In contrast, larger (up to 0.26‰ in δ56Fe) isotopic variations have been found between separate approximately 1 g pieces of the same ordinary chondrite sample. The Fe isotope heterogeneities in ordinary chondrites appear to be controlled by the abundances of chondritic components, specifically chondrules, whose Fe isotope compositions have been fractionated by evaporation and recondensation during multiple heating events.
Muscle atrophy in Limb Girdle Muscular Dystrophy 2A: a morphometric and molecular study
Authors: Fanin M. , Nascimbeni A. C. , Angelini C. 
Published: February 2013

AimsThe peculiar clinical features and the pathogenic mechanism related to calpain‐3 deficiency (impaired sarcomere remodelling) suggest that the ubiquitin‐proteasome degradation pathway may have a crucial role in Limb Girdle Muscular Dystrophy 2A (LGMD2A). We therefore investigated muscle atrophy and the role of the ubiquitin‐proteasome and lysosomal‐autophagic degradation pathways.MethodsWe selected 25 adult male LGMD2A patients (and seven controls), classified them using clinical severity score, analysed muscle fibre size by morphometry and protein and/or transcriptional expression levels of the most important atrophy‐ and autophagy‐related genes (MuRF1, atrogin1, LC3, p62, Bnip3).ResultsMuscle fibre size was significantly lower in LGMD2A than in controls and it was significantly correlated with patients' clinical disability score recorded at the time of biopsy, suggesting that functional and structural muscle impairment are dependent. The large majority of atrophic fibres originate from a mechanism different from regeneration, as assessed by neonatal myosin immunolabelling. As compared with controls, LGMD2A muscles have higher MuRF1 (but not atrogin1) protein and MuRF1 gene expression levels, and MuRF1 protein levels significantly correlated with both muscle fibre size and clinical disability score. LGMD2A muscles have slightly increased levels of LC3‐II and p62 proteins and a significant up‐regulation of p62 and Bnip3 gene expression.ConclusionsIn LGMD2A muscles the activation of the atrophy programme appeared to depend mainly upon induction of the ubiquitin‐proteasome system and, to a lesser extent, the autophagic‐lysosomal degradation pathway.
How to Rule Out Disjunctive Properties
Authors: Audi Paul 
Published: February 2013

AbstractAre there disjunctive properties? This question is important for at least two reasons. First, disjunctive properties are invoked in defense of certain philosophical theories, especially in the philosophy of mind. Second, the question raises the prior issue of what counts as a genuine property, a central concern in the metaphysics of properties. I argue here, on the basis of general considerations in the metaphysics of properties, that there are no disjunctive properties. Specifically, I argue that genuine properties must guaranteesimilarity‐in‐a‐respectamong their instances, and mustinherein their bearers (two notions to be clarified). Disjunctive properties would fail both requirements. I compare the case of disjunctive properties with “mere Cambridge properties,” determinable properties, and functional properties, and show how my conception of properties remains compatible with determinables and functional properties while ruling out disjunctive and mere Cambridge properties.
Re‐alignment‐procedures for Skeletal Dysplasia in Three Patients with Genetically Diverse Syndromes
Authors: Al Kaissi Ali , Ganger Rudolf , Roetzer Katharina M. , Schwarzbraun Thomas , Klaushofer Klaus , Grill Franz 
Published: February 2013

ObjectiveDisruption to endochondral ossification leads to delayed and irregular bone formation and can result in a heterogeneous group of genetic disorders known as osteochondrodysplasias. These genetic disorders arise through disturbances in the complex processes of skeletal growth causing development of unsightly skeletal deformities.Methods Each syndrome was diagnosed on the basis of detailed clinical and radiographic assessment. Lower limb deformities were the prime presenting feature.ResultsHere are presented three patients with diverse genetic syndromes, namely Wolcott–Rallison syndrome (WRS), Kniest dysplasia (KD) and Desbuquois dysplasia (DS). Genetic testing was performed in the patients with WRS and DS. The diagnosis of KD was made purely on a clinical and radiographic basis. Variable orthopaedic interventions to realign these patients' lower limbs were implemented with the aim of improving their balance and gait.ConclusionsThe aim of this paper is twofold. The first part is to outline the importance of diagnosing the causes of various skeletal abnormalities in patients with osteochondrodysplasias by phenotypic and genotypic characterization. The second part is to demonstrate our techniques for surgical corrections in patients with joint laxity and malalignment and show how far techniques for growth modulation, re‐alignment and ligament reconstruction have advanced.
School context and health in adolescence: The role of sense of coherence
Authors: García‐Moya I. , Rivera F. , Moreno C. 
Published: February 2013

The aim of this study was to examine the role of school variables and sense of coherence (SOC) in the explanation of health. For this purpose, data were collected from a representative sample of adolescents, aged 13 to 18 years, selected for the Health Behavior in School‐aged Children survey in Spain. Using Structural Equation Modelling, three nested models were tested that represented different hypothesized models of the relationships among school factors, SOC and health. According to goodness‐of‐fit indices, in the best model, school‐related stress and SOC mediated the influence of support from classmates and teachers on health, and SOC had a direct effect on stress. The results supported the idea that a supportive school climate and SOC are relevant to adolescents' health. Furthermore, SOC was the most influential variable; apart from its direct positive effect on health, SOC seemed to condition the degree to which students perceived school demands to be stressful. Specifically, students with a high SOC were less likely to suffer from high levels of school‐related stress.
Bourdieu and the Sociology of Music Consumption: A Critical Assessment of Recent Developments
Authors: Prior Nick 
Published: February 2013

AbstractThe French sociologist Pierre Bourdieu has been an extraordinarily influential figure in the sociology of music. For over three decades, his concepts have helped to generate both empirical and theoretical interventions in the field of study. His impact on the sociology of music taste, in particular, has been profound, his ideas directly informing our understandings of how musical preferences reflect and reproduce inequalities between social classes. But, recently his legacy has been under question and newer approaches to the music/society problematic have emerged. These have made important claims about the nature of the sociological enterprise when confronted with the specificity of cultural works, as well as how social change impacts on our relations with musical forms. This paper takes stock of the impact of Bourdieu’s ideas on the sociology of music, the debates sparked in their wake and the attempt at something like a “post‐Bourdieusian” sociology more faithful to music’s material properties. It will ask to what extent Bourdieu’s claims about social stratification and music consumption are still relevant and whether they are sophisticated enough to deal with the specific ways that we interact with musical forms.
Regrounding Youth Cultural Theory (in Post‐Socialist Youth Cultural Practice)
Authors: Pilkington Hilary , Omel’chenko Elena 
Published: February 2013

AbstractThis article considers how the study of youth cultural practice in Eastern Europe informs theoretical and empirical debate about youth culture. It charts the trajectory of academic writing on East European youth cultures and suggests the region’s state socialist past (which made social inequalities relatively insignificant at a time when, elsewhere, youth cultural studies were dominated by class‐based readings) combined with the explosion of inequality in the post‐socialist period (by which time class‐resistant post‐subcultural theories led anglophone academic discussion), makes it an interesting vantage point from which to reconsider academic paradigms. Drawing on empirical examples of youth cultural practice in (post)‐socialist Eastern Europe, it argues for a perspective that integrates structural and cultural factors shaping young people’s lives. It suggests moving forward western theoretical debates – often stymied in arguments over nomenclature (‘subculture’, ‘postsubculture’, ‘neo‐tribe’) – by shifting the focus of study from ‘form’ (‘subculture’ etc.) to ‘substance’ (concrete cultural practices) and attending to everyday communicative, musical, sporting, educational, informal economy, and territorial practices. Since such practices are embedded in the ‘whole’ rather than ‘subcultural’ lives of young people, this renders visible how cultural practices are enabled and constrained by the same social divisions and inequalities that structure society at large.
Canine oral fibrosarcomas: a retrospective analysis of 65 cases (1998–2010)
Authors: Gardner H. , Fidel J. , Haldorson G. , Dernell W. , Wheeler B. 
Published: February 2013

AbstractThe objective of this retrospective study was to report the outcome of treatment of canine oral fibrosarcomas (FSA) in relation to median survival and progression‐free survival (PFS), and to report whether grade was prognostic in relation to median survival. Sixty‐five dogs with oralFSApresented to theWSU VTHbetween June 1998 and March 2010. Significant predictors of median survival were location (P = 0.0099), tumour size or oral stage (P = 0.0312), type of surgery (P = 0.0182), margins (P = 0.0329) and grade (P = 0.0251). Significant predictors ofPFSwere location (P = 0.0177), and radiation protocol (P = 0.0343). A combination of surgery and radiation was the strongest predictor of prolonged median survival (P = 0.0183) andPFS(P = 0.0263) at 505 and 301 days, respectively. Treatment of canine oralFSAwith a combination of surgery and radiation therapy provided the longest median survivals.
Clinical and histological characterization of hair coat and glandular tissue of Chinese crested dogs
Authors: Wiener Dominique J. , Gurtner Corinne , Panakova Lucia , Mausberg Theresa‐Bernadette , Müller Eliane J. , Drögemüller Cord , Leeb Tosso , Welle Monika M. 
Published: February 2013

BackgroundTwo varieties exist in the Chinese crested dog breed, namely hairless Chinese crested dogs presenting with hypotrichosis and dentition abnormalities, and the coated powderpuffs. Hairless Chinese crested dogs are obligate heterozygotes for a FOXI3 mutation, and this phenotype is classified as a form of canine ectodermal dysplasia.ObjectivesWe provide a detailed histological description of hair follicles and their density for the three subphenotypes (true hairless, semi‐coated and powderpuffs) of Chinese crested dogs. Apocrine and exocrine glands of the skin and other tissues were compared with findings reported from dogs with X‐linked ectodermal dysplasia.AnimalsSkin biopsies were collected from 22 Chinese crested dogs. Additionally, the glands of the skin and other tissues were examined from another two dogs available for postmortem examination.MethodsSkin biopsies and tissues were processed, stained and evaluated in a blinded fashion.ResultsHair follicular anomalies decreased with increasing number of hairs in the different phenotypes. The FOXI3 mutants had only simple primary hair follicles, whereas the nonmutant powderpuffs had compound follicles identical to other dog breeds. All Chinese crested dogs had an anagen‐dominated hair cycle. Furthermore, apocrine glands in the skin and respiratory mucous glands of the mutant Chinese crested dogs were present and normal.Conclusions and clinical importanceWe have identified striking histopathological differences between the three subphenotypes of Chinese crested dogs. We clearly demonstrated distinct differences between the canine ectodermal dysplasia in Chinese crested dogs and dogs with X‐linked ectodermal dysplasia.
Genome Sequences of Salmonella enterica Serovar Heidelberg Isolates Isolated in the United States from a Multistate Outbreak of Human
Salmonella
Infections
Authors: Hoffmann Maria , Luo Yan , Lafon Patricia C. , Timme Ruth , Allard Marc W. , McDermott Patrick F. , Brown Eric W. , Zhao Shaohua 
Published: February 2013

ABSTRACT

Salmonella enterica
is recognized as one of the most common bacterial agents of foodborne illness. We report draft genomes of four
Salmonella
serovar Heidelberg isolates associated with the recent multistate outbreak of human
Salmonella
Heidelberg infections linked to kosher broiled chicken livers in the United States in 2011. Isolates 2011K-1259 and 2011K-1232 were recovered from humans, whereas 2011K-1724 and 2011K-1726 were isolated from chicken liver. Whole genome sequence analysis of these isolates provides a tool for studying the short-term evolution of these epidemic clones and can be used for characterizing potentially new virulence factors.
Complete Genome Sequence of Bacillus thuringiensis Bacteriophage BMBtp2
Authors: Dong Zhaoxia , Peng Donghai , Wang Yueying , Zhu Lei , Ruan Lifang , Sun Ming 
Published: February 2013

ABSTRACT

Bacillus thuringiensis
is an insect pathogen which has been widely used for biocontrol. During
B. thuringiensis
fermentation, lysogenic bacteriophages cause severe losses of yield. Here, we announce the complete genome sequence of a bacteriophage, BMBtp2, which is induced from
B. thuringiensis
strain YBT-1765, which may be helpful to clarify the mechanism involved in bacteriophage contamination.
Genome Sequences of Two Lactococcus garvieae Strains Isolated from Meat
Authors: Ricci Giovanni , Ferrario Chiara , Borgo Francesca , Eraclio Giovanni , Fortina Maria Grazia 
Published: February 2013

ABSTRACT

Lactococcus garvieae
is an important fish pathogen and an emerging opportunistic human pathogen, as well as a component of natural microbiota in dairy and meat products. We present the first report of genome sequences of
L. garvieae
I113 and Tac2 strains isolated from a meat source.
Genome Sequence of Helicobacter heilmannii Sensu Stricto ASB1 Isolated from the Gastric Mucosa of a Kitten with Severe Gastritis
Authors: Smet Annemieke , Van Nieuwerburgh Filip , Ledesma Jessica , Flahou Bram , Deforce Dieter , Ducatelle Richard , Haesebrouck Freddy 
Published: February 2013

ABSTRACT

Here we report the genome sequence of
Helicobacter heilmannii
sensu stricto ASB1 isolated from the gastric mucosa of a kitten with severe gastritis.
Helicobacter heilmannii
sensu stricto has also been associated with gastric disease in humans. Availability of this genome sequence will contribute to the identification of genes involved in the pathogen's virulence and carcinogenic properties.
Genome Sequence of the Attenuated Carbosap Vaccine Strain of Bacillus anthracis
Authors: Harrington Robin , Ondov Brian D. , Radune Diana , Friss Mary Beth , Klubnik Joy , Diviak Lynn , Hnath Jonathan , Cendrowski Stephen R. , Blank Thomas E. , Karaolis David , Friedlander Arthur M. , Burans James P. , Rosovitz M. J. , Treangen Todd , Phillippy Adam M. , Bergman Nicholas H. 
Published: February 2013

ABSTRACT

The
Bacillus anthracis
Carbosap genome, which includes the pXO1 and pXO2 plasmids, has been shown to encode the major
B. anthracis
virulence factors, yet this strain's attenuation has not yet been explained. Here we report the draft genome sequence of this strain, and a comparison to fully virulent
B. anthracis
.
A rare complication following radiofrequency ablation
Authors: Rajakulasingam Ramyah , Francis Rohin , Ghuran Azad 
Published: February 2013

Atrial–oesophageal fistula (AOF) formation is a rare but often fatal complication post radio frequency ablation (RFA). Mortality ranges from 67% to 100%, with a rapid progression from symptom onset to death. We report a case of a healthy man in his early 40s who presented with a Glasgow Coma Scale of 5/15, clinical evidence of sepsis andStreptococcus viridansbacteraemia, 14 days following uncomplicated RFA for atrial fibrillation. Establishing a diagnosis of AOF can be difficult, as patients may have bacteraemia, but are consequently misdiagnosed with infective endocarditis, as in this case. One should have a high-index of suspicion for AOF in patients presenting with the aforementioned constellation of symptoms following ablation. There are no established predictors of mortality, but prompt detection, emergent operative intervention and prolonged antibiotic therapy are vital for survival.
Savior of the Race: The Messianic Burdens of Black Masculinity
Authors: Neal Ronald B. 
Published: February 2013

Abstract
This paper is concerned with the messianic construction of manhood within African American communities in North America and its normative imprint in shaping and measuring masculinity among African Americans. In this essay, messianic manhood is treated as a utopian construction of masculinity that is found in liberal and conservative constructions of Protestant Christianity. In examining this tradition of manhood, representative messianic men are interrogated who have participated in and have been shaped by this tradition. Overall, messianic manhood is inconceivable apart from an oral tradition of preaching and singing where the person of Jesus is understood as Lord, savior, and ally of the oppressed.
History of Pacific Northwest Heat Waves: Synoptic Pattern and Trends
Authors: Bumbaco Karin A. , Dello Kathie D. , Bond Nicholas A. 
Published: February 2013

AbstractA historical record of Pacific Northwest (defined here as west of the Cascade Mountains in Washington and Oregon) heat waves is identified using the U.S. Historical Climate Network, version 2, daily data (1901–2009). Both daytime and nighttime events are examined, defining a heat wave as three consecutive days above the 99th percentile for the maximum and minimum temperature anomalies separately. Although the synoptic characteristics of the daytime and nighttime heat events are similar, they do indicate some differences between the two types of events. Most notable is a stronger influence of downslope warming over the Cascade Mountains for the daytime events versus a more important role of precipitable water content for the nighttime events, presumably through its impact on downward longwave radiative fluxes. Current research suggests that the frequency and duration of heat waves are expected to increase in much of the United States, and analysis of the heat events reveals that a significant, increasing trend in the frequency of the nighttime events is already occurring in the Pacific Northwest. A heat wave occurred in 2009 that set all-time-record maximum temperatures in many locations and ranked as the second strongest daytime event and the longest nighttime event in the record.