bluuebunny/crossref_metadata_2025_split huggingface dataset:
Injury of the superficial femoral artery and posterior tibial artery associated with an atherectomy device
Authors: Afifi Ahmed M , Dunseith Samuel C , Nazzal Munier 
Published: August 2024

Objectives Rotational atherectomy can offer a viable treatment for occlusive peripheral artery disease; maintaining the minimal invasiveness of an endovascular procedure, while allowing for a more complete lesion debridement compared with balloon angioplasty. This case report outlines a complication of guidewire entrapment associated with rotational atherectomy in the superficial femoral artery (SFA). Methods A 57-year-old male underwent an atherectomy with Rotorex for left lower limb foot pain. During the procedure, the guidewire was suctioned into the atherectomy device, preventing any further advancement of the device and damaging the SFA and posterior tibial artery (PTA). Results The atherectomy device was withdrawn and a new vascular access site was gained in the left PTA. A covered stent was inserted to treat the original SFA lesion, and balloon angioplasty was used to repair the device-induced damaged to the PTA. Conclusion While guidewire complications have been previously reported, this case report details the first reported case, to our knowledge, of guidewire entrapment while using a rotational atherectomy device. Knowledge of this possible complication of rotational atherectomy can aid in clinical decision making when choosing between treatments for peripheral vascular disease.
Exploring the Potential Pharmacological Basis and Mechanism of HJT Activity in the Treatment of CHD Based on UPLC-QE-MS and Network Pharmacology
Authors: Qi Wang , Jianyuan Zhong , Wenxia Zhang , Yinghan Ren , Yang Yang 
Published: August 2024

Objective To identify the blood-entering components of HanJing Decoction (HJT) after administration based on UPLC-QE-MS/MS, and the key components, therapeutic targets and mechanisms of HJT therapeutic coronary heart disease (CHD) were analyzed using network pharmacology and molecular docking. Method The UPLC-QE-MS/MS was used to analyze the blood-entering components of HJT before and after administration. The targets of blood-entering components were predicted by SwissTargetPrediction. Targets related to CHD were collected using multiple databases. The GO and KEGG enrichment analyses were used to predict the mechanisms of HJT therapeutic CHD, and PPI and “Components-Targets-Pathways” network were used to identify and elucidate the core targets. The key blood-entering components aimed at the core target are screened by molecular docking and QSAR analysis. Results A total of 14 blood-entering components were detected in serum samples of rat after administration, and the 32 potential targets of HJT therapeutic CHD were screened out. The result of PPI network showed that the core targets of HJT for the treatment of CHD include MMP1, GSK3B, EGFR and PTGS2, and the 5 key components with high degree were screened out. The GO and KEGG enrichment analyses indicate that HJT therapy for CHD is associated with the IL-17 and cGMP-PKG signaling pathways. The result of molecular docking indicate that the binding energy of coroglaucigenin to PTGS2 is the largest and it may be the key pharmacological component of HJT, and the QSAR analysis showed that Boldine and Coroglaucigenin had excellent activity in inhibiting PTGS2. Conclusions In this study, the blood-entering components of HJT were preliminarily identified, Combined network pharmacology and molecular docking analyses revealed that the PTGS2 may be a core target, and the IL-17 and cGMP-PKG signaling pathways may be the key pathways. Moreover, the coroglaucigenin and boldine may be the key pharmacological components of HJT.
Intranasal Trigeminal Function in Aging Adults
Authors: Feit Noah Z. , Kloosterman Nicole , LaPointe Kristina A. , Pitiranggon Charn , Finnegan Isabel E. , Smith Carter D. , Gregoski Mathew J. , Rowan Nicholas R. , Soler Zachary M. , Schlosser Rodney J. 
Published: August 2024

Background Intranasal trigeminal function is important in detecting environmental stimuli. The impact of age-associated chemosensory dysfunction upon taste and olfaction is well described, but an understanding of trigeminal loss (chemesthesis) is lacking. Objective The goal of this study was to characterize trigeminal function in a cohort of older adults and explore potential impacts. Methods Twenty-eight participants over 50 years of age were recruited from the community as part of an aging cohort study. This nested cohort completed chemosensory questionnaires, patient-reported outcome measures (PROMs), and psychophysical testing for taste (taste strips), olfaction (Sniffin’ Sticks), and trigeminal function (eucalyptol lateralization). Data were analyzed for associations between trigeminal function, olfactory, and taste psychophysical performance, patient-reported metrics, and demographic risk factors. Results Patient-reported trigeminal impairment is less severe than other chemosensory loss, with mean visual analog scores (VAS, rated 0-100 from least to most severe) for smell (32.9 ± 34.2), taste (20.6 ± 28.4), and trigeminal sensation (9.5 ± 12.8). Despite low VAS scores, psychophysical trigeminal dysfunction was present in 10 (35.7%) subjects. Psychophysical olfactory and taste dysfunction were present in 16 (57.1%) and eight (28.6%) participants respectively. Hypercholesterolemia was associated with psychophysical trigeminal dysfunction (mean lateralization performance in hypercholesterolemia 57.7% ± 17.1 vs. 74.1% ± 10.4, p = .008). Conclusion Intranasal trigeminal impairment is present in nearly one-third of aging adults when assessed by psychophysical methods but is under-recognized. Hyperlipidemia may be associated with trigeminal impairment. Future inquiries should better characterize these findings in larger and prospective cohorts.
Subcutaneous ureteral bypass for treatment of proximal ureteral obstruction secondary to retroperitoneal fibrosis after renal transplantation in a cat
Authors: Laminette Peter J , Hardie Robert J 
Published: August 2024

Case summary A 5.5-year-old male neutered domestic shorthair cat was presented with a 2-year history of progressive chronic kidney disease. Abdominal ultrasonography revealed bilateral chronic renal degeneration, nephrolithiasis, cortical hyperechogenicity and infarction. Left orthotopic renal transplantation was performed using the Synovis vascular coupling system for end-to-end anastomosis of the renal arteries and veins. Two months after transplantation, renal values were elevated, and abdominal ultrasonography revealed hydronephrosis and hydroureter of the transplanted kidney. Fluoroscopic antegrade pyelography identified a proximal ureteral stricture. Proximal neoureterocystostomy was performed and renal values normalized postoperatively. The cat was re-evaluated for acute stranguria and severe azotemia 12 months later. Contrast-enhanced CT revealed severe hydronephrosis of the transplanted kidney, obstruction of the proximal ureter and adhesions to the urinary bladder. Upon exploration, retroperitoneal fibrosis was found covering the transplanted kidney. Given the clinical situation, a subcutaneous ureteral bypass device (SUB) was placed. Clinicopathologic analyses, trough cyclosporine levels, aerobic urine cultures and ultrasonographic evaluations of the transplanted kidney were monitored every 1–3 months. Patency of the SUB was reassessed every 3–6 months. At 15 months after placement, the SUB occluded due to kinking of the cystostomy catheter and was replaced. At 28 months after SUB placement, renal function and clinical status deteriorated, and the cat was euthanized. Relevance and novel information To the authors’ knowledge, this is the first report of a SUB device being used for management of ureteral obstruction in a transplanted kidney in a cat.
Psychological Distress and Its Associated Factors Among Parents of Children With Congenital Heart Disease: A Cross-Sectional Mixed Method Study at the National Cardiothoracic Center, Ghana
Authors: Entsua-Mensah Kow , Tetteh John , Ekem-Ferguson George , Swaray Swithin M. , Adzamli Innocent I. , Yao Nana-Akyaa , Tettey Mark M. 
Published: August 2024

Background The aim of this study was to examine the prevalence and factors associated with psychological distress among parents of children with congenital heart disease (PCCHD) receiving treatment at the National Cardiothoracic Centre (NCTC), Accra. Methods A cross-sectional mixed method study involving 248 parents of children with congenital heart disese receiving treatment at the NCTC was employed. Systematic sampling was used to select participants. The outcome variables were depression, anxiety, and somatization, assessed using the brief symptom inventory. A semistructured interview guide was used to understand the contextual factors that contribute to parents’ psychological distress. Poisson regression and inductive thematic analyses were employed for quantitative and qualitative data, respectively. Results The prevalence of depression, anxiety, and somatization was 42.9% [95%CI = 36.7-49.3], 42.4% [95%CI = 36.3-48.9], and 41.2% [95%CI = 35.1-47.6] respectively. Parents who were divorced [aPR (95%CI) = 1.60(1.02-2.51)], hadonly basic level education [aPR (95%CI) = 2.13(1.34-3.39)], were without a religious affiliation [aPR (95%CI)= 2.24(1.58-3.19)], and in the low asset quintile significantly increased the likelihood of psychological distress. Delay/postponement of scheduled surgery, worsening state of child's condition, feeling a sense of helplessness, societal stigma, and lack of funding or health insurance for the treatment of the condition were contextual factors that contributed to increased psychological distress among parents. Conclusion The prevalence of psychological distress was quite high among parents of children with congenital heart disease in Ghana and was associated with both parent and patient factors. Psychosocial care should be integrated into the clinical health services of this group of patients and their parents to improve psychological health outcomes.
Rural Collective Property Rights System Reform and Urban-Rural Income Gap: A County-Scale Big Data Analysis in China
Authors: Pan Dan , Zhou Jinlong , Yu Yi , Chen Shengdong 
Published: August 2024

Property rights reform has been widely regarded as a powerful tool to narrow the urban-rural income gap (URIG). A recent nationwide property rights reform in China, namely, the rural collective property rights system reform (RCPRSR) was implemented in 2015, offering rural residents rights to rural collective assets, especially land assets. However, whether it can help to narrow URIG or not remains controversial. Based on 2,322 county-level big panel data in China from 2010 to 2019, this paper takes RCPRSR as a quasi-natural experiment and empirically evaluates its impact and mechanism on URIG by using a time-varying difference-in-differences (DID) model. The findings suggest that RCPRSR can decrease URIG by 4.2%, and this conclusion is still reliable after six robustness tests. Heterogeneity analysis shows that the positive effect of RCPRSR on narrowing URIG is significant in eastern and northeastern China, but not in central and western China. Mechanism analysis shows that RCPRSR can decrease URIG mainly through optimizing the industrial structure and improving the agricultural mechanization level. This study provides a reference on how to mitigate URIG through property rights reform in developing countries. JEL Classification: O20, D31, D63.
Examining the Feasibility and Acceptability of Digital Cognitive Stimulation Therapy for Dementia Care in Jordan: A Qualitative Study
Authors: Abdalrahim Asem , ALBashtawy Mohammed , Alkhawaldeh Abdullah , Ayed Ahmad 
Published: August 2024

Introduction The use of technology to deliver psychosocial interventions such as cognitive stimulation therapy (CST) to individuals with dementia may improve their cognition and quality of life. Objectives This study aimed to investigate the participants’ experiences with digital CST in Jordanian care homes, as well as the acceptability of the digital CST intervention in Jordanian care homes and recommendations for refinement. Methods A qualitative study design and semistructured interviews were used to obtain data from 20 people with dementia and 12 care home staff who were purposefully selected. Data were analyzed thematically and comparatively to explore the experiences and outcomes of the participants. This study was conducted from February to April 2023. Results Analysis of care home staff and residents’ experiences revealed seven major themes: (a) personalized support and engagement, (b) positive impact on quality of life, (c) engagement and meaningful activities, (d) adaptable format and accessibility, (e) emotional connection and empowerment, (f) caregiver involvement and support, and (g) suggestions for improvement. The study's findings emphasize the necessity of tailored support, individualized difficulty levels, individualized material selection, emotional support, greater social connection, and caregiver participation in digital CST for people with dementia. Conclusion Using digital touchscreen technology to deliver CST content has shown potential improvements, making interventions simpler for staff and more beneficial for individuals with dementia, thereby enhancing cognition and quality of life.
ACL Repair: Rationale and When to Consider Over Reconstruction
Authors: Broome Jalen N. , Cherelstein Rachel E. , Chang Edward S. 
Published: August 2024

Background: Anterior cruciate ligament (ACL) restoration has been divided into repair versus reconstructive approaches. We present an ACL repair using FiberTape sutures as an internal brace and an adjustable cortical button fixation on the femur. Indications: ACL rupture is a condition in which restoration is essential to regaining adequate knee function. ACL repair may be indicated in patients with an acute tear (<4 weeks), Sherman classification type I or II tear, 35 years old or older, and with a mild-to-moderate activity level. Technique Description: ACL tightrope repair initially requires identification of the ACL tear. Following, there is femoral wall preparation and the creation of a drill tunnel in the femoral and tibial walls. FiberRing sutures are passed through the intact portion of the ACL as many times as desired. An ACL Tightrope is then fed through the FiberRing sutures. The ACL Tightrope and cortical button are passed through the femoral tunnel. FiberTape sutures are passed through a tibial tunnel to act as an internal brace. Range of motion and tension is assessed and adjusted as needed. Results: Patients meeting indications for ACL repair and undergoing repair via Tightrope implants may have outcomes comparable to counterparts undergoing ACL reconstruction. Patient-completed functional knee scores, such as International Knee Documentation Committee (IKDC), Knee Injury and Osteoarthritis Outcome Score (KOOS), and Lysholm, are similar between the 2 restoration techniques. However, younger patients undergoing an ACL repair appear to have a higher failure rate compared with reconstruction. Conclusion: ACL repair can be an adjuvant treatment option with acute femoral sided tears. Caution should be exercised when performing this procedure on younger, higher level athletes. In our technique, use of adjustable cortical button minimizes bone loss on femoral wall while providing adequate fixation. Patient Consent Disclosure Statement: The author(s) attests that consent has been obtained from any patient(s) appearing in this publication. If the individual may be identifiable, the author(s) has included a statement of release or other written form of approval from the patient(s) with this submission for publication.
Flood-induced buttertub spill reveals riverine macroplastic transport dynamics
Authors: Hauk Rahel , van der Ploeg Martine , Teuling Adriaan J. , de Winter Winnie , van Emmerik Tim H. M. 
Published: August 2024

AbstractDuring the July 2021 European floods approximately eight million empty dairy packaging (buttertubs) were flushed from a dairy processing facility in Belgium into the Vesdre river. Some were transported further downstream, into the Ourthe river and eventually the Meuse river. There are many unknowns when it comes to plastic transport in rivers, especially in response to floods. We therefore used this incident as an unique opportunity to study these buttertubs as a tracer for plastic transport dynamics in a riverine environment in response to an extreme flood event. Normally, it is unknown when and where individual plastic items found on riverbanks entered the environment. In this case, however, the ID stamps on the buttertups allowed for them to be traced back to the flooding of the factory. We studied the transport and deposition of these buttertubs in the Dutch Meuse over 2 years following the flood. We also collected buttertubs at different points in time to investigate their fragmentation and mass loss. Within 3 weeks of the flood, the buttertubs were transported up to 328 km from the spilling location. Overall, the majority (78%) of buttertubs we found within the first 3 weeks were deposited within less than 100 km of the point of emission. Over the following 2 years, the mean transport distance of the found buttertubs moved downstream from 100 km in July/August 2021, to 153 km in July 2023. The buttertubs average transport velocity decreased from 11.7 km/d within the first 3 weeks, to 0.2 km/d by July 2023. Based on the 89 buttertubs we collected and analyzed in detail over the 2 years, we did not find a significant mass loss. Of all 89 buttertubs found, 47 showed cracks and only 12 appeared to have pieces missing. This study shows that even during extreme flood events, the majority of spilled plastic litter is retained within a limited distance after being emitted into the river. The findings of this study can be utilized to improve plastic transport modelling, and overall better understand plastic transport in the freshwater environment.
Shear strength parameters identification of loess interface based on borehole micro static cone penetration system
Authors: Lan Hengxing , Song Zhanting , Bao Han , Ma Yangfan , Yan Changgen , Liu Shijie , Wang Juntian 
Published: August 2024

Abstract
Background
Loess is prone to large deformation and flow slide due to natural and artificial interfaces inside. The strength of these interfaces controls the mechanical properties of loess. Obtaining their mechanical parameters through in-situ testing is essential for evaluating the mechanical stability in loess engineering with interfaces.

Methods
By developing a borehole micro static cone penetration system and creating various types of loess with interfaces, extensive borehole penetration model tests were conducted to observe changes in cone tip resistance during penetration. The response surface method was used to analyze the impact of various test conditions on the calculated resistance. A three-dimensional surface fitting method was employed to establish the relationship between penetration parameters and shear strength parameters, which was validated through in-situ testing.

Results
The developed borehole micro static cone penetration system achieves overall miniaturization while providing significant penetration power and ensuring an effective penetration distance. Cone tip resistance development during penetration can be divided into three stages: initial, rapid increase, and slow increase. The transition times between these stages vary for different soils. Calculated resistance is positively correlated with dry density and normal stress and negatively correlated with water content. A quadratic positive correlation was established between calculated resistance and shear strength parameters during penetration. In composite soils, the interaction between water content and normal stress is strong. Compared to intact soil samples, the shear strength parameters of composite soils are more prominently influenced by water content.

Conclusion
A system for testing interface mechanical parameters was innovatively developed, fulfilling the need to obtain interface shear strength parameters for deep soil. This study can provide support for ensuring the long-term stability of the loess slope or subgrade with interfaces.
Elevating Pakistan’s flood preparedness: a fuzzy multi-criteria decision making approach
Authors: Alam Zeshan , Ali Yousaf , Pamucar Dragan 
Published: August 2024

AbstractIn South Asia, Pakistan has a long and deadly history of floods that cause losses to various infrastructures, lives, and industries. This study aims to identify the most appropriate flood risk mitigation strategies that the government of Pakistan should adopt. The assessment of flood risk mitigation strategies in this study is based on certain criteria, which are analyzed using the fuzzy full consistency method. Moreover, flood risk mitigation strategies are evaluated by using the fuzzy weighted aggregated sum product assessment (WASPAS) method, considering previously prioritized criteria. According to the results, lack of governance, lack of funding and resources, and lack of flood control infrastructure are the most significant flood intensifying factors and act as major criteria for assessing flood risk mitigation strategies in Pakistan. Adopting hard engineering strategies (e.g., dams, reservoirs, river straightening and dredging, embankments, and flood relief channels), maintaining existing infrastructure, and adopting soft engineering strategies (flood plain zoning, comprehensive flood risk assessment, and sophisticated flood modeling) are identified as the top three flood risk mitigation strategies by the fuzzy WASPAS method. The highest weight (0.98) was assigned to the adoption of hard engineering strategies to mitigate flood risks. The study introduces a novel dimension by analyzing the real-time impact of the unprecedented 2022 floods, during which approximately one-third of the nation was submerged. This focus on a recent and highly significant event enhances the study’s relevance and contributes a unique perspective to the existing literature on flood risk management. The study recommends that the government of Pakistan should prioritize hard engineering strategies for effective flood risk mitigation. It also recommends that the government should incorporate these strategies in the national policy framework to reduce flood losses in the future.