bluuebunny/crossref_metadata_2025_split huggingface dataset:
Factorial invariance of the Wechsler Intelligence Scale for Children, Fifth Edition, across the UK, US and Australia & New Zealand
Authors: Wilson Christopher J. , Bowden Stephen C. , Batty Abigail M. , Byrne Linda K. , Weiss Lawrence G. 
Published: July 2024

AbstractObjectivesThis study examined the factorial invariance of the factor structure of the Wechsler Intelligence Scale for Children, Fifth Edition (WISC‐V) across the UK, US and Australia & New Zealand (A&NZ). The factorial equivalence of cognitive assessments should be demonstrated before assuming cross‐culture generalizability and interpretations of score comparisons.MethodsData were obtained from the UK, US and A&NZ normative standardizations of the WISC‐V. The samples consisted of 415 UK, 2200 US and 528 A&NZ children, aged 6–16. Confirmatory factor analysis was applied separately in each sample to establish the baseline model. Next, tests of factorial invariance were undertaken using the recommended hierarchical approach, firstly across the UK and A&NZ samples and then across the UK and US samples.ResultsThe five‐factor first‐order scoring model was found to be excellent fit across all three samples independently. Strict factorial invariance of the WISC‐V was demonstrated firstly across the UK and A&NZ and secondly the UK and US nationally representative standardization samples. Comparison of latent means found small but significant differences in female children across the UK and A&NZ samples.ConclusionsConsistent with previous research, these results demonstrate the generality of the WISC‐V factor structure across the UK, US and A&NZ. Furthermore, as the WISC‐V factor structure aligns with the Cattell–Horn–Carroll (CHC) model of cognitive abilities, the results add further support to the cross‐cultural generalizability of the CHC model. Small but significant differences in latent factor scores found across samples support the development and use of local normative data.
An open‐label, prospective trial to evaluate the efficacy and safety of ixazomib in combination with cyclophosphamide and dexamethasone in patients with newly diagnosed POEMS syndrome
Authors: He Haiyan , Hou Nan , Chen Xi , Song Yaqi , Qiang Wanting , Liu Jin , Lu Jing , Fu Weijun , Du Juan 
Published: July 2024

SummaryThis open‐label, prospective trial evaluated the combination of ixazomib, cyclophosphamide and dexamethasone (ICD) in 12 newly diagnosed POEMS syndrome patients. The study is registered with the Chinese Clinical Trials Registry (ChiCTR2000030072). The treatment protocol consisted of 12 cycles of the ICD regimen compromising ixazomib (4 mg on Days 1, 8 and 15), oral cyclophosphamide (300 mg on Days 1, 8 and 15) and dexamethasone (20 mg weekly). A total of 12 patients received a median of 10 (range: 3–23) cycles of the ICD regimen. The haematological response could be evaluated in 10 patients. The overall haematological response rate was 80% (8/10), with 30% (3/10) achieving complete haematological response, and the overall serum VEGF response rate and neurological response were 100% and 83.3% respectively. Two patients experienced grade 3/4 AEs, including diarrhoea (n = 1) and leukopenia (n = 1). The combination of ixazomib, cyclophosphamide and dexamethasone demonstrated both efficacy and safety in newly diagnosed POEMS syndrome, making it a viable treatment option.
Centring children's lived experiences in understanding the importance of play in hospitals
Authors: Graber Kelsey , O'Farrelly Christine , Ramchandani Paul 
Published: July 2024

AbstractBackgroundChildren have a right to participate in matters affecting their lives. With increasing regularity, children's perspectives are being sought regarding their health and health care experiences. Though there is evidence that children find play to be one of the ‘best’ aspects of hospitalisation, studies rarely focus on children's perspectives on play in hospital.MethodsThis qualitative study explored children's lived experiences of play during hospitalisation. Over five months, ethnographic observations were conducted on a paediatric oncology ward as well as interviews with 16 children ages 3–13 years.ResultsUsing interpretative phenomenological analysis, children's expressions and experiences illuminated three key points: safety and comfort are integral to children feeling able to play in hospital; the value and efficacy of play is decided by children; and that play is a way for patients to be (and be treated as) children first.ConclusionHospitals can only be child‐friendly if children find them friendly. Listening to and integrating children's perspectives in the discourse around the importance of play in hospital is essential for respecting children's rights and delivering person‐centred paediatric healthcare.
Exploring changing trends in depression and anxiety among adolescents from 2012 to 2019: Insights from My World repeated cross‐sectional surveys
Authors: Fitzgerald Amanda , Mahon Ciara , Shevlin Mark , Dooley Barbara , Reilly Aileen O. 
Published: July 2024

AbstractAimResearch has indicated a rise in the prevalence of depression and anxiety among adolescents over the past three decades. However, the factors underpinning increases in mental health difficulties remain poorly understood. This study examines psychological, social and environmental risk and protective factors that may explain changes in depression and anxiety among adolescents.MethodsData were taken from two nationally representative My World Surveys of adolescents aged 12–19 years in 2012 (N = 5,490) and 2019 (N = 9,844). Survey data on depression and anxiety and a range of potential risk (e.g., alcohol use, psychotic symptoms) and protective factors (e.g., resilience, self‐esteem) were assessed at both time points. Multiple group analyses assessed whether the predictive ability of risk/protective factors changed from wave 1 to wave 2.ResultsResults showed that the prevalence of depression and anxiety increased significantly between 2012 and 2019, particularly among females. Predictors accounted for between 37% and 61% of the variance in outcomes across waves. While some risk/protective factors were consistent predictors of depression and anxiety at both waves (e.g., bullying, discrimination, optimism), reporting female gender and having higher formal help‐seeking tendencies more strongly predicted anxiety at wave 2, while lower self‐esteem and lower resilience (personal competence) strongly predicted both depression and anxiety at wave 2.ConclusionFindings highlight the need to prioritize adolescent mental health service provision, especially in females. Self‐esteem and resilience are potentially important targets for supporting adolescent mental health. Further research is required to understand the causal factors associated with increases in anxiety and depression.
Towards an interdisciplinary “science of the mind”: A call for enhanced collaboration between philosophy and neuroscience
Authors: Buccella Alessandra , Maoz Uri , Mudrik Liad 
Published: July 2024

AbstractIn recent decades, the neuroscientific community has moved from describing the neural underpinnings of mental phenomena—as characterized by experimental psychology and philosophy of mind—to attempting to redefine those mental phenomena based on neural findings. Nowadays, many are intrigued by the idea that neuroscience might provide the “missing piece” that would allow philosophers (and, to an extent, psychologists, too) to make important advances, generating new means that these disciplines lack to close knowledge gaps and answer questions like “What is Free Will?” and “Do humans have it?.” In this paper, we argue that instead of striving for neuroscience to replace philosophy in the ongoing quest to understanding human thought and behavior, more synergetic relations should be established, where neuroscience does not only inspire philosophy but also draws from it. We claim that such a collaborative coevolution, with the two disciplines nourishing and influencing each other, is key to resolving long‐lasting questions that have thus far proved impenetrable for either discipline on its own.
Acting as causing change
Authors: Alvarez Maria 
Published: July 2024

AbstractThe paper defends a version of the view that agency is a causal power, the “causing view.” After sketching the view, and explaining how it differs from its rivals, various challenges are assessed. A family of objections says that causing change is neither necessary nor sufficient for acting. The second challenge centers on an Aristotelian thesis about the relation between an action (A's opening a window) and the corresponding passion (the window's being opened by A). The final objection concerns the dynamic nature of acting: the claim is that a causal view of agency cannot accommodate actions “in progress” or mere activity. I conclude that none of the objections examined presents unsurmountable problems for the causal view of agency which, at least in the version here defended, remains a highly plausible and attractive view.
Situational prevention: Pharmacotherapy during periods of increased risk for migraine attacks
Authors: Lipton Richard B. , Ailani Jessica , Mullin Kathleen , Pavlovic Jelena M. , Tepper Stewart J. , Dodick David W. , Blumenfeld Andrew M. 
Published: July 2024

AbstractThe small molecule calcitonin gene–related peptide receptor antagonists (gepants) are the only drug class with medicines indicated for both the acute and preventive treatment of migraine. Given this dual capacity to both treat and prevent, along with their favorable tolerability profiles and lack of an association with medication‐overuse headache, headache specialists have begun to use gepants in ways that transcend the traditional categories of acute and preventive treatment. One approach, called situational prevention, directs patients to treat during the interictal phase, before symptoms develop, in situations of increased risk for migraine attacks. Herein, we present three patients to illustrate scenarios of gepant use for situational prevention. In each case, a gepant was started in anticipation of a period of increased headache probability (vulnerability) and continued for a duration of 1 day to 5 consecutive days. Although this approach may expose patients to medication when headache may not have developed, the tolerability and safety profile and preventive effect of gepants may represent a feasible approach for some patients. Situational prevention is an emerging strategy for managing migraine before symptoms develop in individuals who can identify periods when the probability of headache is high. This paper is intended to increase awareness of this strategy and stimulate future randomized, placebo‐controlled trials to rigorously assess this strategy.
Radiotherapy in the treatment of primary cutaneous CD4+ small/medium T‐cell lymphoproliferative disorder
Authors: Wu Susan Y. , Damron Ethan P. , Xu Jie , Fang Penny Q. , Dai Julia , Nair Ranjit , Malpica Castillo Luis E. , Fayad Luis E. , Torres‐Cabala Carlos A. , Medeiros L. Jeffrey , Vega Francisco , Miranda Roberto N. , Duvic Madeleine , Pinnix Chelsea C. , Dabaja Bouthaina S. , Iyer Swaminathan P. , Huen Auris O. , Gunther Jillian R. 
Published: July 2024

AbstractBackgroundPrimary cutaneous CD4+ small/medium T‐cell lymphoproliferative disorder (PCSM‐LPD) is an increasingly recognized entity with heterogeneous management strategies that may include radiotherapy.ObjectiveOur aim was to characterize treatment options for PCSM‐LPD, with a focus on the role of radiotherapy.MethodsThis is a retrospective review of 46 patients seen in the Cutaneous Lymphoma Program at the University of Texas MD Anderson Cancer Center, with a clinicopathologic review consistent with PCSM‐LPD. All patients were biopsied and underwent observation, topical/intralesional steroids, and/or radiotherapy. Patients were confirmed to have residual disease prior to radiotherapy.ResultsAll patients achieved a complete response (CR). Sixteen patients (35%) received focal radiotherapy, with a CR in 15 (94%). The CR rate following ultra‐low‐dose radiotherapy (4 Gy in 1–2 fractions) was 92%. There was no grade 3 toxicity after radiotherapy. Thirty patients were managed without radiotherapy, with excision and observation or steroids.ConclusionPrimary cutaneous CD4+ small/medium T‐cell lymphoproliferative disorder has excellent outcomes, and management strategies may include observation following biopsy, steroids, or radiation. Ultra‐low‐dose radiotherapy results in excellent outcomes with limited toxicity and is effective for persistent lesions after steroidal therapy.
Effect of sodium alginate‐locust bean gum ice glazing containing different antioxidants on quality of mackerel (Pneumatophorus japonicus) during frozen storage
Authors: Cheng Hao , Zhou Pengcheng , Mei Jun , Xie Jing 
Published: July 2024

SummaryThe quality of fish is easily damaged during the frozen process, and the ice glazing technology can better maintain the quality of frozen fish. However, the traditional ice glazing technology is not yet stable and some of the properties need to be improved. This research optimised ice glazing technology by adding different antioxidants to the traditional ice glazing, which improved the stability of the ice glazing and lessened the dry consumption of mackerel during frozen storage. The lipid oxidation and protein denaturation of mackerel were inhibited with the addition of antioxidants to the ice glazing, the freshness of mackerel was maintained better, and the production of histamine was also decreased during frozen storage. It was found that the ice glazing with the addition of antioxidant bamboo leaves (AOB) had better water retention, lower TVB‐N value, and histamine content compared to the addition of theaflavins (TF) and sodium isovitamin (VC). Moreover, the sample treated by the ice glazing with AOB showed less lipid oxidation and protein denaturation. Therefore, ice glazing with the addition of AOB could be an optional method for relieving the quality deterioration of mackerel during frozen storage. This research also provides insights into the coupling of antioxidants and ice‐coating techniques.
Non‐standard employment, low standard of living? The role of labour market and social policy measures in preventing material deprivation in different employment trajectories in Europe
Authors: Wolf Fridolin 
Published: July 2024

AbstractWhile the poverty risks of non‐standard employment have been explored extensively, this study focuses on the role of activation‐oriented social policy in alleviating material deprivation for persons with non‐standard employment histories. Using EU‐SILC data, individuals over a four‐year period were analysed. I focused on substantial earners and distinguished between six non‐standard employment histories expected to benefit from activation measures. Multi‐level models revealed that compared to standard employment histories, all non‐standard employment histories had higher material deprivation risks but to substantially different extents. At the macro level, participation in activation measures, expenditures in formal childcare and minimum income protection reduced material deprivation. Participation in training can be interpreted as an equaliser, as the deprivation gap between standard and most non‐standard employment history types diminished. As expenditure‐ and participation‐based measures differed significantly, evaluating the success of activation strategies in reducing inequalities and alleviating poverty highly depends on the measurement of activation.
Characterization of the UDP‐glycosyltransferase UGT33D1 in silkworm Bombyx mori
Authors: Zhu Feifei , Han Jinying , Hong Jingdie , Cai Fuchuan , Tang Qi , Yu Qian , Ma Shangshang , Liu Xiaoyong , Huo Shuhao , Chen Keping 
Published: July 2024

AbstractUridine diphosphate (UDP)‐glycosyltransferases (UGTs) are important metabolizing enzymes functioning by adding a sugar moiety to a small lipophilic substrate molecule and play critical roles in drug/toxin metabolism for all realms of life. In this study, the silkworm Bombyx mori UGT33D1 gene was characterized in detail. UGT33D1 was found localized in the endoplasmic reticulum (ER) compartment just like other animal UGTs and was mainly expressed in the silkworm midgut. We first reported that UGT33D1 was important to BmNPV infection, as silencing UGT33D1 inhibited the BmNPV infection in silkworm BmN cells, while overexpressing the gene promoted viral infection. The molecular pathways regulated by UGT33D1 were analysed via transcriptome sequencing upon UGT33D1 knockdown, highlighting the important role of the gene in maintaining a balanced oxidoreductive state of the organism. In addition, proteins that physically interact with UGT33D1 were identified through immunoprecipitation and mass spectrometry analysis, which includes tubulin, elongation factor, certain ribosomal proteins, histone proteins and zinc finger proteins that had been previously reported for human UGT‐interacting proteins. This study provided preliminary but important functional information on UGT33D1 and is hoped to trigger deeper investigations into silkworm UGTs and their functional mechanisms.
Relationship between shift type and sleep quality in rotating‐shift nurses with chronotype as a moderator variable
Authors: Weng Pei‐Wei , Chang Wen‐Pei 
Published: July 2024

AbstractBackgroundRotating‐shift nurses are susceptible to sleep disorders due to numerous factors, such as their biological clock, emotions, and age. At present, a lack of research exists on whether chronotype and shift type jointly influence the sleep quality of nurses.AimTo verify whether chronotype is a moderator variable of the relationship between shift type and sleep quality in nurses in order to provide empirical evidence for future mental and physical health improvement.MethodClinical rotating‐shift nurses at a medical center in northern Taiwan were recruited as participants between November 1, 2023, and December 13, 2023. All of the nurses were working a monthly rotating shift schedule. Hierarchical multiple regression analysis was employed to investigate whether the influence of shift type on sleep quality in nurses varied with chronotype. The STROBE checklist was used for reporting this study.ResultsThe participants were 255 rotating‐shift nurses in this study. Hierarchical multiple regression results revealed that rotating‐shift nurses who were older (B = 0.19, p = 0.029), had greater physical fatigue (B = 0.27, p = 0.016), and had more negative emotions (B = 0.17, p = 0.011) suffered from poorer sleep quality. After controlling the above factors, we further found that chronotype indeed had moderating effects on the influence of shift type on sleep quality (B = −1.83, p = 0.049).ConclusionsThis study demonstrates that early‐ and intermediate‐type nurses are more suitable for working the day and evening shifts, whereas late‐type nurses are more suitable for working the night shift.Implication for nursing and health policyCoordinating chronotype with shift type will ensure that shift schedules better match the biological clocks of nurses; such individual considerations could help to improve their sleep quality.
Taiwanese nurse educators’ behaviour or intention to teach LGBT health content: A qualitative study
Authors: Wang Ya‐Ching , Miao Nae‐Fang , You Mei‐Hui 
Published: July 2024

AbstractAimTo explore factors associated with Taiwanese nurse educators’ behaviour or intention to teach lesbian, gay, bisexual and transgender (LGBT) health content.BackgroundNurse educators were found to have limited experiences and readiness to teach LGBT health content. However, limited evidence exists to comprehensively understand factors associated with nurse educators’ behaviour and intentions to teach LGBT health content.MethodsA qualitative descriptive study design was adopted. A total of 24 nurse educators were interviewed. One‐on‐one interviews were conducted employing a semi‐structured topic guide and were audio‐recorded. Interview data were analysed using the socio‐ecological model and constant comparative technique. This article was reported according to the Consolidated Criteria for Reporting Qualitative Research checklist.FindingsMost nurse educators had no experience of teaching LGBT health content and expressed their low or no intention to teach it. Factors associated with nurse educators’ behaviour and intention to teach LGBT content were categorised by the socio‐ecological model level: intrapersonal factors, interpersonal factors, community factors and societal and policy factors.ConclusionThis study identified multilevel factors associated with Taiwanese nurse educators’ behaviour and intention to teach LGBT health content. Recommendations were provided to address multilevel barriers to diminish nurse educators’ challenges in teaching LGBT health content.Implications for nursing and nursing policySupervisors of nurse educators should assess and discuss nurse educators’ concerns and competencies regarding teaching LGBT health content. To address schools’ or organisations’ adverse climates and conventional societal atmosphere, related policies and regulations should be developed and implemented.
Why are Turkish nurses migrating? A mixed‐methods study
Authors: Yürümezoğlu Havva Arslan , Çamveren Hatice 
Published: July 2024

AbstractAimThis study aimed to identify the factors influencing nurses’ migration patterns in Turkey.BackgroundThe flow of nurse migration from developing countries to developed countries is steadily increasing. As a result, countries that are sources of migration tend to develop domestic inequities with respect to the population's ability to access health services. In particular, fragile economic conditions and the pandemic triggered the migration of nurses from Turkey, a developing country.MethodsThis study employed a mixed‐method explanatory sequential design and was conducted in Turkey between April and November 2022. The decision to migrate was the focus of both the quantitative aspect, involving 237 participants, and the qualitative aspect, with 20 participants. Quantitative data were gathered through a questionnaire, and qualitative data were obtained using open‐ended questions during in‐depth individual interviews. We followed the Strengthening the Reporting of Observational Studies in Epidemiology checklist in the quantitative phase and the Consolidated Criteria for Reporting Qualitative Research checklist in the qualitative phase. Descriptive statistics and thematic analyses were used to analyze the data.ResultsIn the quantitative stage of the study, nurses’ reasons for deciding to migrate were identified as economic conditions, working conditions, society's outlook on the profession, political factors, and professional growth opportunities. In the qualitative stage, four major themes influencing nurse migration patterns emerged: devaluation and poor collegiality in nursing; inadequate management support; negative work environment; and health, social, and economic policies.ConclusionThe results of the study showed that the three factors most influential in the decision to migrate were economic issues, a negative work environment, and political climate.Implications for nursing and health policyIn developing countries, there is an urgent need for nurse administrators and health workforce decision‐makers to create healthy working conditions and manage resources efficiently, focusing on improving nurses’ economic situations while developing appropriate nationwide and international strategies.