bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevalence, prescribing and barriers to effective management of hypertension in older populations: a narrative review
Authors: Alhawassi Tariq M , Krass Ines , Pont Lisa G 
Published: October 2015

Abstract
Objectives
Hypertension is the leading modifiable cause of mortality worldwide. Unlike many conditions where limited evidence exists for management of older individuals, multiple large, robust trials have provided a solid evidence-base regarding the management of hypertension in older adults. Understanding the impact of age on how the prevalence of hypertension and the role of pharmacotherapy in managing hypertension among older persons is a critical element is the provision of optimal health care for older populations. The aim of this study was to explore how the prevalence of hypertension changes with age, the evidence regarding pharmacological management in older adults and to identify known barriers to the optimal management of hypertension in older patients.

Methods
A review of English language studies published prior to 2013 in Medline, Embase and Google scholar was conducted. Key search terms included hypertension, pharmacotherapy, and aged.

Results
The prevalence of hypertension was shown to increase with age, however there is good evidence for the use of a number of pharmacological agents to control blood pressure in older populations. System, physician and patient related barriers to optimal blood pressure control were identified.

Conclusions
Despite good evidence for pharmacological management of hypertension among olderpopulations, under treatment of hypertension is an issue. Concerns regarding adverse effects appearcentral to under treatment of hypertension among older populations.
A Dietary Medium-Chain Fatty Acid, Decanoic Acid, Inhibits Recruitment of Nur77 to the HSD3B2 Promoter In Vitro and Reverses Endocrine and Metabolic Abnormalities in a Rat Model of Polycystic Ovary Syndrome
Authors: Lee Bao Hui , Indran Inthrani Raja , Tan Huey Min , Li Yu , Zhang Zhiwei , Li Jun , Yong Eu-Leong 
Published: October 2015

Abstract
Hyperandrogenism is the central feature of polycystic ovary syndrome (PCOS). Due to the intricate relationship between hyperandrogenism and insulin resistance in PCOS, 50%–70% of these patients also present with hyperinsulinemia. Metformin, an insulin sensitizer, has been used to reduce insulin resistance and improve fertility in women with PCOS. In previous work, we have noted that a dietary medium-chain fatty acid, decanoic acid (DA), improves glucose tolerance and lipid profile in a mouse model of diabetes. Here, we report for the first time that DA, like metformin, inhibits androgen biosynthesis in NCI-H295R steroidogenic cells by regulating the enzyme 3β-hydroxysteroid dehydrogenase/Δ5-Δ4-isomerase type 2 (HSD3B2). The inhibitory effect on HSD3B2 and androgen production required cAMP stimulation, suggesting a mechanistic action via the cAMP-stimulated pathway. Specifically, both DA and metformin reduced cAMP-enhanced recruitment of the orphan nuclear receptor Nur77 to the HSD3B2 promoter, coupled with decreased transcription and protein expression of HSD3B2. In a letrozole-induced PCOS rat model, treatment with DA or metformin reduced serum-free testosterone, lowered fasting insulin, and restored estrous cyclicity. In addition, DA treatment lowered serum total testosterone and decreased HSD3B2 protein expression in the adrenals and ovaries. We conclude that DA inhibits androgen biosynthesis via mechanisms resulting in the suppression of HSD3B2 expression, an effect consistently observed both in vitro and in vivo. The efficacy of DA in reversing the endocrine and metabolic abnormalities of the letrozole-induced PCOS rat model are promising, raising the possibility that diets including DA could be beneficial for the management of both hyperandrogenism and insulin resistance in PCOS.
Was ist neu an der neuen Dolmetschart Community Interpreting? State of the Art in deutschsprachigen Ländern
Authors: Petrova Alena 
Published: October 2015

<p>In my paper I would like to discuss the specifics of community interpreting (CI) as a relatively new art of interpreting. The following aspects should be taken into consideration: the definition of the term on specific scopes of CI and compared to other types of interpretation as well as a brief overview of the development of this type of interpreting in Sweden, USA and Canada as pioneer countries and German-speaking countries.</p><p>For the definition of CI compared especially to conference interpreting, the following factors are important: the particular communication situation, the additional skills of the interpreter, guidelines for CI as well as questions of quality management and the role of the interpreter: Is the tendency to over-emphasize the position of power of the community interpreter fair? </p><p>In the context of a country-specific overview, the following are also discussed: the professional status of the community interpreter and the situation on the labor market – in areas of court interpreting (including asylum procedures, eg Legal Law Clinic in Innsbruck, Austria as a positive example) and hospital interpreting – and training for community interpreters at university (eg in Graz and Vienna in Austria).</p><p>In conclusion, I would like to speak about necessary steps to professionalize CI in German-speaking countries.</p>
Χρήστος Δ. Καρδαράς, Ιωακείμ Γ' - Χαρ. Τρικούπης, Η αντιπαράθεση. Από την ανέκδοτη αλληλογραφία του Οικουμενικού Πατριάρχη (1878-1884)
Authors: Καραθανάσης Αθ. Ε. 
Published: October 2015

<p>No abstract </p>
Actes de Vatopédi I. Des origines à 1329. Édition diplomatique par J. Bompaire, J. Lefort, V. Kravari, C. Giros. Texte-Album (Archives de l’Athos XXI), P. Lethielleux
Authors: Πολέμης Ιωάννης Δ. 
Published: October 2015

<p>No abstract </p>
Κωνσταντίνου Α. Βακαλοπούλου, Ο Βόρειος Ελληνισμός κατά την πρώιμη φάση του Μακεδονικού Αγώνα (1878-1894). Απομνημονεύματα Αναστασίου Πηχεώνα
Authors: Αγγελόπουλος Αθαν. 
Published: October 2015

<p>No abstract </p>
Νικολάου Κρουσουλούδη, Ο βίος και το έργον του εθνομάρτυρος μητροπολίτου Χίου Πλάτωνος Φραγκιάδου (1776-1822)
Authors: Αγγελόπουλος Αθαν. 
Published: October 2015

<p>No abstract </p>
Impact of a structured review session on medical student psychiatry subject examination performance
Authors: Siddiqi Shan H. , Black Kevin J. , Womer Fay Y. 
Published: October 2015

Introduction: The National Board of Medical Examiners (NBME) subject examinations are used as a standardized metric for performance in required clerkships for third-year medical students. While several medical schools have implemented a review session to help consolidate knowledge acquired during the clerkship, the effects of such an intervention are not yet well-established. An improvement in NBME psychiatry examination scores has previously been reported with a single end-of-clerkship review session, but this was limited by a small sample size and the fact that attendance at the review session was optional, leading to likely selection bias.Methods: A 1.5-hour structured review session was conducted for medical students in the last week of each 4-week psychiatry clerkship between September 2014 and July 2015. Students were required to attend unless excused due to scheduling conflicts. Scores on the NBME psychiatry subject exam were compared with those of students taking the examination in the corresponding time period in each of the previous two academic years.Results: 83 students took the exam during the experimental period, while 176 took the exam during the control period. Statistically significant improvements were found in mean score (p=0.03), mean for the two lowest scores in each group (p<0.0007), and percentage of students scoring 70 or less (p=0.03). Percentage of students achieving the maximum possible score (99) was higher in the experimental group, but did not reach significance (p=0.06).Conclusions: An end-of-clerkship review session led to increased mean scores on the NBME psychiatry subject examination, particularly for students at the lower end of the score range. Future research should investigate the impact of such an intervention in other specialties and other institutions.
In situ phytoplankton distributions in the Amundsen Sea Polynya measured by autonomous gliders
Authors: Schofield Oscar , Miles Travis , Alderkamp Anne-Carlijn , Lee SangHoon , Haskins Christina , Rogalsky Emily , Sipler Rachel , Sherrell Robert M. , Yager Patricia L. 
Published: October 2015

Abstract
The Amundsen Sea Polynya is characterized by large phytoplankton blooms, which makes this region disproportionately important relative to its size for the biogeochemistry of the Southern Ocean. In situ data on phytoplankton are limited, which is problematic given recent reports of sustained change in the Amundsen Sea. During two field expeditions to the Amundsen Sea during austral summer 2010–2011 and 2014, we collected physical and bio-optical data from ships and autonomous underwater gliders. Gliders documented large phytoplankton blooms associated with Antarctic Surface Waters with low salinity surface water and shallow upper mixed layers (&lt; 50 m). High biomass was not always associated with a specific water mass, suggesting the importance of upper mixed depth and light in influencing phytoplankton biomass. Spectral optical backscatter and ship pigment data suggested that the composition of phytoplankton was spatially heterogeneous, with the large blooms dominated by Phaeocystis and non-bloom waters dominated by diatoms. Phytoplankton growth rates estimated from field data (≤ 0.10 day−1) were at the lower end of the range measured during ship-based incubations, reflecting both in situ nutrient and light limitations. In the bloom waters, phytoplankton biomass was high throughout the 50-m thick upper mixed layer. Those biomass levels, along with the presence of colored dissolved organic matter and detritus, resulted in a euphotic zone that was often &lt; 10 m deep. The net result was that the majority of phytoplankton were light-limited, suggesting that mixing rates within the upper mixed layer were critical to determining the overall productivity; however, regional productivity will ultimately be controlled by water column stability and the depth of the upper mixed layer, which may be enhanced with continued ice melt in the Amundsen Sea Polynya.
Are There Regional Differences in US Hardwood Product Exports?
Authors: Bumgardner Matthew , Bowe Scott , Luppold William 
Published: October 2015

Abstract
Exporting is a critical component of the product mix for many domestic hardwood firms. Previous research has identified factors associated with hardwood lumber exporting behavior, but less is known about the advantages and disadvantages to exporting associated with the region within which a firm is located, or about exporting of secondary hardwood products. A procedure comparing a measure of production (employment) to the level of exporting in three US hardwood regions (based on aggregations of state-level data) was used to contrast regional relative exporting of primary and secondary products. Several factors were then considered as possible explanations for the observed regional differences. Overall, the results suggested that proximity to seaports (i.e., the East Coast) benefited exporting of both hardwood lumber and secondary products, but the impact was greater for lumber. Thus, for secondary products, regional exporting barriers appeared to be lower. Firm size and sawtimber quality and species were additional factors that were associated with regional exporting. Data for individual states provide clues to interstate movement of hardwood products as they make their way to US ports. This influence also is discussed, but such movement makes state-level analysis of exporting difficult.
Agents enabling cyber-physical production systems
Authors: Vogel-Heuser Birgit , Lee Jay , Leitão Paulo 
Published: October 2015

Abstract
In order to be prepared for future challenges facing the industrial production domain, Cyber-Physical Production Systems (CPPS)
consisting of intelligent entities which collaborate and exchange information globally are being proclaimed recently as part of
Industrie 4.0. In this article the requirements of CPPS and abilities of agents as enabling technology are discussed. The applicability
of agents for realizing CPPS is exemplarily shown based on three selected use cases with different requirements regarding real-time and
dependability. The paper finally concludes with opportunities and open research issues that need to be faced in order to achieve
agent-based CPPSs.
Plug & produce by modelling skills and service-oriented orchestration of reconfigurable manufacturing systems
Authors: Pfrommer Julius , Stogl Denis , Aleksandrov Kiril , Escaida Navarro Stefan , Hein Björn , Beyerer Jürgen 
Published: October 2015

Abstract
Shortening product lifecycles and small lot sizes require manufacturing systems to adapt increasingly fast. Many existing machine
tools, handling and logistics systems provide a generic functionality that is not bound to a specific product. But this flexibility and
reconfigurability on the level of individual resources is lost in automated systems that are limited to the production of a fixed set
of product variants. We propose a unified abstraction for the skills provided by the available resources and the product-specific
manufacturing requirements. From these high-level descriptions, executable manufacturing procedures are derived, exposed as services
and dynamically orchestrated at runtime in order to achieve the manufacturing goals.
Model-based development of products, processes and production resources
Authors: Dumitrescu Roman , Bremer Christian , Kühn Arno , Trächtler Ansgar , Frieben Tanja 
Published: October 2015

Abstract
This contribution applies methods and languages of Model-Based Systems Engineering to the field of production system engineering. The goal is an integrated modeling of objects, processes and systems. This approach improves knowledge transfer between the stakeholders involved and enables model-based design and verification.
Industrie 4.0 – technological approaches, use cases, and implementation
Authors: Anderl Reiner 
Published: October 2015

Abstract
Industrie 4.0 aims at improving value chains and value-added networks in industry. Technologically the approach is based on the
introduction of cyber-physical systems. Their capabilities form the basis for smart systems. This paper presents technological
approaches for Industrie 4.0 and introduces use cases as a specification technique for application scenarios. A demonstrator for
additive manufacturing is presented. Lessons learnd from this demonstrator have led to the definition of capabilities for vertical and
horizontal integration within Industrie 4.0.
Cyber-physical production systems: roots from manufacturing science and technology
Authors: Monostori László 
Published: October 2015

Abstract
One of the most significant directions in the development of computer science and information and communication technologies is
represented by Cyber-Physical Systems (CPS) which are systems of collaborating computational entities which are in intensive
connection with the surrounding physical world and its on-going processes, providing and using, at the same time, data-accessing and
data-processing services available on the internet. Cyber-Physical Production Systems (CPPS), relying on the newest and
foreseeable further developments of computer science, information and communication technologies on the one hand, and of manufacturing
science and technology, on the other, may lead to the 4th Industrial Revolution, frequently noted as Industrie 4.0. The paper
underlines that there are significant roots generally – and particularly in the CIRP community – which point towards
CPPS. Expectations and the related new R&D challenges are also outlined.
Milton Friedman on Freedom and the Negative Income Tax
Authors: Preiss Joshua 
Published: October 2015

AbstractIn addition to his Noble Prize-winning work in economics, Milton Friedman produced some of the most influential philosophical work on the role of government in a free society. Despite his great influence, there remains a dearth of scholarship on Friedman’s social and political philosophy. This paper helps to fill this large void by providing a conceptual analysis of Friedman’s theory of freedom. In addition, I argue that a careful reading of his arguments for freedom ought to lead Friedman, and like-minded liberals and libertarians, to give absolute priority to his negative income tax proposal. A substantial basic income furthers effective economic freedom (on Friedman’s own understanding), redeems his central claim that markets enable cooperation without coercion, and enables him to address his lifelong interlocutors by mitigating concerns for the ways in which economic dependence and inequality undermine both freedom and democratic legitimacy.
Simulation of varying femoral attachment sites of medial patellofemoral ligament using a musculoskeletal multi-body model
Authors: Geier A. , Tischer T. , Bader R. 
Published: October 2015

Abstract
The medial patellofemoral ligament (MPFL) is a key structure in the treatment of habitual and traumatic patellofemoral instability. However, there exists little knowledge about its behaviour during deep knee flexion after femoral refixation. Since improper femoral attachment sites may lead to unnatural length change patterns in the ligament and consequently to osteoarthritis due to pathological femoro-patellar contact pressure, the understanding of the patella kinematics and MPFL behaviour is crucial.
The purpose of this numerical study was to compute the six-degree-of-freedom motion pattern of the human patella during deep knee flexion for systematic analysis of varying landmarks for the femoral attachment in medial patellofemoral ligament reconstruction surgery by means of multibody simulation.
Therefore, based on a previously presented musculoskeletal model [1] the dynamic pathways of the patella were computed. Then, the spatial motion was approximated by rheonomic polynomials and exploited for systematic evaluation of the MPFL length change patterns. Hence, 16 femoral attachment points at a radius of 5 mm and 10 mm around the radiographic centre point [2] were defined and the absolute length changes were recorded during deep knee flexion to 120 degree.
This approach allows for a systematic evaluation of numerous MPFL attachment sites while exploiting the physiological patella kinematics. The patella kinematics including shift, flexion, tilt and rotation as well as the MPFL length change patterns were consistent to in vitro and in vivo data in the literature [3–7] and therefore indicate validity of the numerical approach. The parameter study on the femoral attachment site should enable to determine the most isometric point and non-isometric variations corresponding to patellofemoral instability, arthritis or high graft load.
Type II ancient compact solutions to the Yamabe flow
Authors: Daskalopoulos Panagiota , del Pino Manuel , Sesum Natasa 
Published: October 2015

Abstract
We construct new type II ancient compact solutions to the Yamabe flow. Our solutions
are rotationally symmetric and converge, as

t
→

-
∞

{t\to{-}\infty}

, to a tower of two spheres.
Their curvature operator changes sign.
We allow two time-dependent parameters in our ansatz. We use perturbation theory, via fixed point arguments,
based on sharp estimates on ancient solutions of the approximated linear equation
and careful estimation of the error terms which allow us to make the right choice of parameters.
Our technique may be viewed as a parabolic analogue of gluing two exact solutions to the rescaled equation, that is the spheres, with narrow cylindrical necks to obtain a new ancient solution to the Yamabe flow. The result
generalizes to the gluing of k spheres for any

k
≥
2

{k\geq 2}

, in such a way the configuration of radii of the spheres glued is driven as

t
→

-
∞

{t\to{-}\infty}

by a First order Toda system.
Intrinsic flat stability of the positive mass theorem
for graphical hypersurfaces of Euclidean space
Authors: Huang Lan-Hsuan , Lee Dan A. , Sormani Christina 
Published: October 2015

Abstract
The rigidity of the Positive Mass Theorem states that the only complete asymptotically flat manifold of nonnegative scalar curvature and zero mass is Euclidean space. We study the stability of this statement for spaces that can be realized as graphical hypersurfaces in

𝔼

n
+
1

{\mathbb{E}^{n+1}}

.
We prove (under certain technical hypotheses) that if a sequence of complete asymptotically flat graphs of nonnegative scalar curvature has mass approaching 0, then the sequence must converge to Euclidean space in the pointed intrinsic flat sense. The appendix
includes a new Gromov–Hausdorff and intrinsic flat
compactness theorem for sequences of metric spaces with uniform Lipschitz bounds on their metrics.
Addendum: The case of closed surfaces (Boundary value problems on planar graphs and flat surfaces with integer cone singularities I: The Dirichlet problem)
Authors: Hersonsky Sa'ar 
Published: October 2015

Abstract

We extend our discrete uniformization theorems for planar, m-connected, Jordan domains [J. reine angew. Math. 670 (2012), 65–92] to closed surfaces of genus m ≥ 1.
Vector valued theta functions associated with binary quadratic forms
Authors: Ehlen Stephan 
Published: October 2015

Abstract
We study the space of vector valued theta functions for the Weil representation of a positive definite even lattice of rank two
with fundamental discriminant.
We work out the relation of this space to the corresponding scalar valued theta functions of weight one
and determine an orthogonal basis with respect to the Petersson inner product.
Moreover, we give an explicit formula for the Petersson norms of the elements of this basis.
Utilization of walnut shell as a feedstock for preparing high surface area activated carbon by microwave induced activation: effect of activation agents
Authors: Xia Hongying , Cheng Song , Zhang Libo , Peng Jinhui 
Published: October 2015

Abstract
The present work attempts to convert walnut shell into a high surface area activated carbon by microwave heating and chemical activation. Different activation agents such as KOH, NaOH, K2CO3 and Na2CO3 were utilized to identify a suitable activation agent. The result indicated that KOH was the most suitable activation agent among those agents, with the highest porosity and surface area of activated carbon. The effect of KOH/C mass ratio on the pore structure characteristics of the activated carbon was investigated. An optimal KOH/C mass ratio of 4 was identified, beyond which the surface area as well as the pore volume were found to decrease. The surface area and the pore volume were estimated to be 3276 m2/g and 1.952 ml/g, respectively, meanwhile the microporous proportion was 77.51% under the optimized KOH/C mass ratio. The activated carbon was further characterized using Fourier transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM). The findings strongly support that the activation agent has a great effect on the preparation of activated carbon from walnut shell.