bluuebunny/crossref_metadata_2025_split huggingface dataset:
Implementation of Continuing Professional Development in Self Professional Development Factors Amongst Aviation Polytechnic’s Lecturers
Authors: Pratama Andrian , Samani Muchlas , Buditjahjanto Asto 
Published: June 2024

The purpose of this research is to find out the picture of conditions in quantity and quality of lecturers today and the implementation of continuing professional develompent lecturers in terms of self professional development at makassar aviation polytechnic. This research uses a qualitative approach by collecting data in terms of documents, literature, and interviews. The research subject was a makassar aviation polytechnic lecturer who numbered 16 people supported by interviews with 3 people in managerial positions. The implementation of the factors studied is the implementation factor of continuing professional develompent lecturers in terms of self professional development. The results of this study show that the implementation of Continuing Professional Development in aviation polytechnics is still not optimal in terms of quantity. This can be seen from the number of certified lecturers as many as 7 people or 43% of the number of permanent lecturers. Aviation polytechnics do not yet have lecturers with doctoral criteria. There are variables of self professional development, namely in the implementation of Continuing Professional Development in self reading activities are considered good, self development in research activities is considered not optimal, and in academic quality activities is considered Not optimal. These findings indicate that implementation of Continuing Professional Development has not been optimal.
Model Kepemimpinan Nehemia Berbasis Pengelolaan Bagi Pengelolaan Organisasi Gereja
Authors: Bandhaso Silas 
Published: June 2024

Tujuan penelitian ini adalah untuk menemukan bagaimana pengelolaan yang dilakukan oleh Nehemia sebagai pemimpin sehingga mampu menyelesaikan pembangunan tembok Yerusalem. Kendatipun berbagai tantangan dihadapi selama pembangunan tembok Yerusalem tetapi pada akhirnya pembangunan tembok tersebut dapat diselesaikan dengan baik. Metode yang digunakan adalah metode library Research atau metode penelitian kepustakaan. Hasil penelitian ini menunjukkan bahwa pengelolaan yang dilakukan oleh Nehemia sehingga mampu membangun kembali tembok Yerusalem dengan baik adalah pengelolaan sumber daya manusia, pengelolaan konflik, dan pengelolaan motivasi atau semangat.
Consumer Perceptions and Willingness to Pay for Luxury Tourism in Pakistan's Northern Regions
Authors: Hasan Zaki , Mehmood Sumera , Bibi Munaza , Ali Raza , Zeerak Syeda , Murtaza Ghulam , Haseeb Abdul , Siddiqui Muhammad Tayyab 
Published: June 2024

This study aimed to investigate the dynamics of Luxury Tourism in the Northern Areas of Pakistan. The selected tourist destinations were PC Bhurban, Luxus Hunza, and PC Malam Jabba. A questionnaire adapted from the previous studies was administered to the on-site tourists to reveal their perceptions, preferences, and behaviours concerning luxury tourism experiences. A sample size of 375 tourists was drawn via simple random sampling. Each participant was asked to complete a 25-item questionnaire. The researcher used SMART PLS 4.0 software to analyse the data using SEM with Partial Least Squares analysis. This research was conducted to find the relationship between self-congruity, destination brand quality, brand identification and factors associated with tourist satisfaction, and willingness to pay a premium price. By considering elements of previous studies and using sophisticated statistical tools, the current research contributed to the improvement of marketing policies and destination management policies of luxury tourism in Pakistan.
Perbandingan Perlindungan Harta (Hifdz Al-Mal) Antara Perbankan Syariah Dan Konvensional
Authors: Aryo Jasmiko  , Shodini Putri Lestar  , Lindy Arina Pramudita  , Suci Marhania  , Bella Sartika.  , Arin Ardianty  , Walid Syauq  
Published: June 2024

ABSTRACT
This article reviews the comparison between asset protection (Hifdz al-Mal) in sharia and conventional banking based on literature study. Islamic banking, which operates with Islamic sharia principles, places special emphasis on the concepts of fairness, transparency and loss prevention to customers. Meanwhile, conventional banking focuses on the interest system and profitability. Although both have the main goal of protecting customer assets, the methods and approaches they use differ significantly. This research describes the key aspects of both systems, examines the principles underlying them, and provides insight into how they offer protection to customers' assets.

ABSTRAK
Artikel ini mengulas perbandingan antara perlindungan aset (Hifdz al-Mal) pada perbankan syariah dan konvensional berdasarkan studi literatur. Perbankan syariah, yang beroperasi dengan prinsip-prinsip syariah Islam, memberikan penekanan khusus pada konsep keadilan, transparansi, dan pencegahan kerugian kepada nasabah. Sementara itu, perbankan konvensional berfokus pada sistem bunga dan profitabilitas. Meskipun keduanya memiliki tujuan utama untuk melindungi aset nasabah, metode dan pendekatan yang mereka gunakan berbeda secara signifikan. Penelitian ini menjelaskan aspek-aspek utama dari kedua sistem tersebut, memeriksa prinsip-prinsip yang mendasarinya, dan memberikan wawasan tentang bagaimana mereka menawarkan perlindungan terhadap aset nasabah.
Antibiotic Susceptibility Pattern of Salmonella typhi Isolated from Hostel Tap Water of a Tertiary Institution in Makurdi
Authors: Eneyi Ebah Esther , Onifade Emmanuel Olumuyiwa , Ugochinyere Dim Chinemerem , Aondoackaa Augustine David 
Published: June 2024

Typhoid fever is caused by Salmonella enterica serovar typhi. This study was undertaken and the aim of the study is to ascertain the antibiotics susceptibility pattern of Salmonella typhi. Isolation of Salmonella typhi strains from a total of 20 tap water samples which was from 4 different hostels in University of Agriculture, Makurdi was done by standard microbiological and biochemical techniques. The strains isolated were examined for their susceptibility to ten antibiotics using the disc diffusion method. The highest susceptibility was to Tarivid and Streptomycin (65%), followed by Amoxicillin (50%), Gentamycin (40%), Septrin (30%), the drug with the highest resistance was Pefloxacin (100%), Sparfloxacin (65%), intermediate resistance in Ciprofloxacin and Chloramphenicol (40%). In the hostels Block A isolates recorded the highest susceptibility to antibiotics while Block C had the least, but there was no significant difference in their mean (P > 0.05). This study indicates that the hostel water supply is contaminated with Salmonella typhi strain and these strains are becoming increasingly resistant to Ciprofloxacin and other quinolones. Therefore, improvements in public sanitation facilities, vaccinations, availability of portable water for safe drinking, and rational use of antibiotics are some recommended ways of preventing antibiotics resistance in Salmonella typhi.
Semiótica de bolsillo para estudiantes de las escuelas de comunicación social
Authors: Hernández Díaz Gustavo 
Published: June 2024

En este segundo artículo de la serie "Pensamiento divulgativo de la comunicación", dirigido a estudiantes de las escuelas de comunicación social, especialmente de las asignaturas de teoría y sociología de la comunicación, exploraremos la semiótica de la comunicación desde una perspectiva introductoria. Abordaremos aspectos generales de la semiología europea creada por Ferdinand de Saussure y Roland Barthes, así como de la semiótica anglosajona establecida por Charles S. Peirce y desarrollada por Charles Morris. Estos enfoques proporcionan herramientas para comprender la naturaleza de los signos y su papel en la comunicación interpersonal, masiva y digital.
Characterization of Microplastics from Otammiri River Imo State, Nigeria
Authors: Adamma Nduka-Chukwudi, Chidimma , Nwabueze Okereke, Josephat , Celestina Mgbemena, Ifeyinwa , Uchechukwu Ezeji, Ethelbert 
Published: June 2024

This study characterized microplastics from Otammiri River, Imo state, Nigeria. The study was carried out according to the National Oceanic and Atmospheric Administration (NOAA) protocol for surface water trawling for microplastics. The microplastics characterized were at the range of 0.3 mm to 5mm which were resistance to wet oxidation and exhibited flotation in a 5M NaCl. Fourier-transform infrared spectroscopy (FTIR) examination was used to characterize the microplastics for identification. FTIR results revealed that polypropylene (PP), polyethylene (PE), polyethylene terephthalate (PET) polystyrene (PS), and polyurethane were the predominant polymers (microplastics) found across Otammiri river.
Development and Validation of HPLC Method for the Quantification of Impending Genotoxic Impurities in Dapson Drug Substances
Authors: Patel Haresh B. , Dave Rohit H. , Vadariya Sandip , Hirpara Hitin , Patel Trushar 
Published: June 2024

The assessment of toxicological concentrations of possible genotoxic contaminants in drug substances was regarded as an important and challenging discipline . The International Conference and Harmonization (ICH) recommended that most pharmaceutical products be allowed to include 1.5 μg/day of a genotoxic contaminant. The goal study was to develop a quick and accurate HPLC method for measuring potential genotoxic impurities (PGIs) in Dapson drug substances. The chromatographic conditions were appropriately optimized with the Phosphate and Acetate buffer on C18 & C8 columns to achieve a decent separation and response of each impurities peak with the Dapsone. A C8 column has been used with Phosphate buffer with the linear gradient combination with Acetonitrile as mobile phase and multiple wavelengths used based on UV maxima of respective impurity. According to International conference of Harmonization (ICH) criteria for the quantification of each impurity, method validation for HPLC was carried out regarding specificity, the limit of detection (LOD), the limit of quantification (LOQ), linearity, accuracy (recovery), precision, and solution stability. Three separate batches of Dapsone were successfully subjected to the desired procedures for the Genotoxic (GTI) determination and found not detected. The corelation coefficient observed > 0.99 in linearity and 70% to 130% recovery observed in the accuracy during method validation hence method can be considered linear and accurate and can be used for testing of genotoxic impurity in Dapsone drug substances.
Antibiotics Resistance Pattern and Molecular Detection of ESBL Genes in E. coli from both Surface and Underground Water used for Domestic Purposes in Selected Locations in Ibadan, Oyo State, Nigeria
Authors: Abigail Ajongbolo Olayinka , Adebambo Morakinyo Abraham , Gambo Ezekiel Dauda , Ibrahim Adamu Muhammad , Ntasin Paul Yiran , T. Opajobi, Imoleayo , Baba Ibrahim Mohammed , Abubakar Umar , Ishaku Nenchin Mulime 
Published: June 2024

Water quality and human health have been strongly related to each other as water acts as a medium for the transmission of antibiotic-resistant microorganisms particularly Extended Spectrum Beta-lactamase (ESBL)-producing Escherichia coli. This study aims at assessing physicochemical parameters, antibiotic susceptibility patterns, and molecular detection of the ESBL gene in isolated E. coli from surface and underground water sources in three selected local government areas in Oyo State, Nigeria. Water samples were collected in some selected three local governments and analyzed for physicochemical properties, isolation and characterization of E. coli, antibiotic susceptibility patterns, phenotypic expression of ESBLs E. coli, and molecular detection of the ESBL gene using the standard method. The physicochemical analysis results showed that hardness mean value ranged from 29.467±0.233 to 2.133±0.318, acidity has the highest mean value of 7.533±0.120, alkalinity mean value range from 31.333±0.186 to 6.167±0.176, conductivity has the highest mean value of 1.774±0.002, total suspended solids (TSS) mean value range from 141.427±0.015 to 0.821±0.003, dissolved oxygen (DO) has the highest mean value of 5.840±0.089, pH mean value range from 6.460±0.54 to 3.963±0.133, and temperature has the highest mean value of 27.200±0.153. Antibiotic susceptibility pattern results reveal that all 12 (100%) ESBL E. coli strains exhibited resistance to nalidixic acid, ampiclox, cefotaxime, ceftriaxone, cefuroxime, and augmentin, while cefexime (91.67%), cefepime (83.33%), gentamicin (75.0%), imipenem (75.0%), levofloxacin (66.67%), ofloxacin (58.33%), and nitrofurantoin (58.33%) had the above resistance rates. Molecular analysis results revealed the presence of ESBL genes in all tested E. coli isolates, and the percentages of occurrence were blaNDM (83.33%), blaTEM (75%), blaCTX-M (66.67%), and blaOXA (50%). blaIMP and blaSHV. (16.67%), while blaVIM and blaKPC were not detected. The findings of this study revealed that there is a need for improved water quality monitoring and public health interventions to mitigate the risks associated with antibiotic-resistant bacteria in water sources.
Electrocatalytic Water Oxidation at Neutral pH by a Nanostructured Co(PO3)2 Anode
Authors: Ahn Hyun S. , Tilley T. Don 
Published: August 2012

AbstractCobalt metaphosphate Co(PO3)2 nanoparticles are prepared via the thermolytic molecular precursor (TMP) method. A Ni form electrode decorated with Co(PO3)2 nanoparticles is evaluated as an anode for water oxidation electrocatalysis in pH 6.4 phosphate‐buffered water. Catalytic onset occurs at an overpotential of ca. 310 mV, which is 100 mV lower than that observed for Co3O4 nanoparticles, with a comparable surface area under identical conditions. A per‐metal turnover frequency (TOF) of 0.10–0.21 s−1 is observed at an overpotential, η, of 440 mV, which is comparable to the highest rate reported for a first‐row metal heterogeneous catalyst. Post‐catalytic characterization of the catalyst resting state by X‐ray photoelectron spectroscopy (XPS) and Raman spectroscopy reveals that surface rearrangement occurs, resulting in an oxide‐like surface overlayer.
Fate of Intravenously Administered Gold Nanoparticles in Hair Follicles: Follicular Delivery, Pharmacokinetic Interpretation, and Excretion
Authors: Kempson Ivan M. , Chien Chia‐Chi , Chung Chao‐Yu , Hwu Yeukuang , Paterson David , de Jonge Martin D. , Howard Daryl L. 
Published: August 2012

AbstractGold nanoparticles (GNPs) are intravenously administered to mice. Deposition at the pilosebacious unit and whiskers is visualized with X‐ray fluorescence after 30 minutes and 14 days. After 30 minutes the dermal papilla, bulge region, and root sheath all contain NPs. GNPs are driven externally out from follicles, counteractive to transfollicular delivery. After 14 days, gold bands in hairs reflect pharmacokinetic profiles indicating blood concentration kinetics. Elimination rate constants infer half‐lives from 3 hairs from an individual mouse within reasonable agreement (6.08, 7.15, and 8.66 hours). 3D reconstruction of NP distributions with confocal microscopy identifies aggregates within the medullary canal. Intermittent NP deposition continues randomly over the two week period demonstrating prolonged NP mobility in vivo. NPs are still retained at the hair bulb after 14 days. The observations further account for the excretory mechanisms of NPs and their behavior in the pilosebacous unit, and demonstrate monitoring pharmacokinetic behavior in individual animals.
Graphene: An Emerging Electronic Material
Authors: Weiss Nathan O. , Zhou Hailong , Liao Lei , Liu Yuan , Jiang Shan , Huang Yu , Duan Xiangfeng 
Published: August 2012

AbstractGraphene, a single layer of carbon atoms in a honeycomb lattice, offers a number of fundamentally superior qualities that make it a promising material for a wide range of applications, particularly in electronic devices. Its unique form factor and exceptional physical properties have the potential to enable an entirely new generation of technologies beyond the limits of conventional materials. The extraordinarily high carrier mobility and saturation velocity can enable a fast switching speed for radio‐frequency analog circuits. Unadulterated graphene is a semi‐metal, incapable of a true off‐state, which typically precludes its applications in digital logic electronics without bandgap engineering. The versatility of graphene‐based devices goes beyond conventional transistor circuits and includes flexible and transparent electronics, optoelectronics, sensors, electromechanical systems, and energy technologies. Many challenges remain before this relatively new material becomes commercially viable, but laboratory prototypes have already shown the numerous advantages and novel functionality that graphene provides.
Predictors of organ damage in systemic lupus erythematosus: The Hopkins Lupus Cohort
Authors: Petri Michelle , Purvey Sneha , Fang Hong , Magder Laurence S. 
Published: August 2012

AbstractObjectiveThe Systemic Lupus International Collaborating Clinics/American College of Rheumatology (ACR) Damage Index (SDI) is the accepted measure of permanent organ damage in systemic lupus erythematosus (SLE). We analyzed data from a large SLE cohort to identify variables associated with rates of damage accrual as measured by the SDI.MethodsThe study included 2,054 SLE patients (92% female, 56% white, and 37% African American) with a mean age at diagnosis of 33 years. The SDI score was calculated retrospectively at the time of cohort entry and prospectively during followup. The relationships between time‐invariant patient characteristics and rates of damage accrual were assessed based on the damage score at the last available followup visit. The relationships between time‐varying patient characteristics and damage accrual were assessed based on the timing of damage accrual during cohort participation.ResultsOverall, the SDI score increased at a rate of 0.13 per year. Higher rates of damage were observed for those who were older, male, or African American, had a lower income or education level, were hypertensive, were positive for lupus anticoagulant, or had proteinuria. During followup, the risk of damage was higher for those who were older, had more disease activity, had low complement levels, were positive for anti–double‐stranded DNA, satisfied more ACR criteria for SLE, or were receiving corticosteroids. Lower risk was observed among patients receiving hydroxychloroquine. After adjustment for other variables, age, hypertension, and corticosteroid use emerged as the most important predictors of damage accrual.ConclusionOur findings indicate that rates of damage vary in demographic subgroups, but much variation appears to be explained by hypertension and corticosteroid use. These data clearly point to the need for tight control of disease activity without reliance on corticosteroids.
Comparison of long‐term clinical outcome with etanercept treatment and adalimumab treatment of rheumatoid arthritis with respect to immunogenicity
Authors: Krieckaert Charlotte L. , Jamnitski Anna , Nurmohamed Michael T. , Kostense Piet J. , Boers Maarten , Wolbink Gertjan 
Published: August 2012

AbstractObjectiveTo compare rates of sustained low and minimal disease activity and remission according to the American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) criteria during 3‐year followup in rheumatoid arthritis (RA) patients treated with etanercept and adalimumab in routine care.MethodsFour hundred seven RA patients previously unexposed to tumor necrosis factor antagonists were treated with etanercept (n = 203) or adalimumab (n = 204) and assessed at 3‐ and later 6‐month intervals. Treatment allocation was at the discretion of the treating rheumatologist. Clinical parameters were measured at each time point, as were anti‐adalimumab antibodies in adalimumab‐treated patients. Achievement of clinical outcome was defined as the occurrence of sustained (at least 12 consecutive months) low disease activity (28‐joint Disease Activity Score [DAS28] <3.2), minimal disease activity (DAS28 <2.6), or ACR/EULAR remission based on the Simplified Disease Activity Index (SDAI). Non‐overlapping response rates were calculated.ResultsAmong the adalimumab group, 13% reached sustained low disease activity but not sustained minimal disease activity, 15% reached sustained minimal disease activity but not sustained remission according to the SDAI, and 16% reached sustained ACR/EULAR remission. In the etanercept group the corresponding rates were 16%, 11%, and 12%, respectively (P = 0.42, overall test for linear trend). Adalimumab‐treated patients without anti‐adalimumab antibodies (n = 150 [74%]) had the best outcomes, and adalimumab‐treated patients with anti‐adalimumab antibodies the worst, with outcomes in etanercept‐treated patients in between (P < 0.0001). Differences were most apparent in the sustained SDAI remission and sustained minimal disease activity categories. For example, 40% of anti‐adalimumab antibody–negative patients, 23% of etanercept‐treated patients, and 4% of anti‐adalimumab antibody–positive patients achieved at least sustained minimal disease activity.ConclusionOverall, etanercept and adalimumab treatment appear similar in inducing a good long‐term clinical outcome. However, in the case of adalimumab this is strongly dependent on the presence or absence of anti‐adalimumab antibodies.
Alterations in resting‐state regional cerebral blood flow demonstrate ongoing pain in osteoarthritis: An arterial spin‐labeled magnetic resonance imaging study
Authors: Howard Matthew A. , Sanders Duncan , Krause Kristina , O'Muircheartaigh Jonathan , Fotopoulou Aikaterini , Zelaya Fernando , Thacker Michael , Massat Nathalie , Huggins John P. , Vennart William , Choy Ernest , Daniels Maxine , Williams Steven C. R. 
Published: August 2012

AbstractObjectiveIncreasing evidence suggests a central nervous system (CNS) component underpinning persistent pain disease states. This study was undertaken to determine regional cerebral blood flow (rCBF) changes representing ongoing pain experienced by patients with painful osteoarthritis (OA) of the carpometacarpal (CMC) joint and to examine rCBF variability across sessions. We used pulsed continuous arterial spin labeling (pCASL), a perfusion magnetic resonance imaging (MRI) technique.MethodsThe study included 16 patients with CMC OA and 17 matched controls. Two pCASL scans and numerical rating scale (NRS) estimates of ongoing pain were acquired in each of two identical sessions. Voxelwise general linear model analyses were performed to determine rCBF differences between OA and control groups, rCBF differences between sessions within each group, and whether sessionwise rCBF differences were related to variability in perceived ongoing pain.ResultsIn the OA group, rCBF increases representing ongoing pain were identified in the primary and secondary somatosensory, insula, and cingulate cortices; thalamus; amygdala; hippocampus; and dorsal midbrain/pontine tegmentum, including the periaqueductal gray/nucleus cuneiformis. Sessionwise rCBF differences in the OA group in the postcentral, rostral/subgenual cingulate, mid/anterior insula, prefrontal, and premotor cortices were related to changes in perceived ongoing pain. No significant sessionwise rCBF differences were observed in controls.ConclusionThis is the first quantitative endogenous perfusion MRI study of the cerebral representation of ongoing, persistent pain due to OA. Observed rCBF changes potentially indicate dysregulated CNS appraisal and modulation of pain, most likely the maladaptive neuroplastic sequelae of living with painful OA. Understanding the neural basis of ongoing pain is likely to be important in developing novel treatment strategies.