bluuebunny/crossref_metadata_2025_split huggingface dataset:
Emergency medicine staff’s perception of SimWars: A Singapore view
Authors: Dong Chaoyan , Goswami Rahul , Sim Guek Gwee , Kowitlawakul Yanika 
Published: August 2015

Background: SimWars is an onstage competition among teams of health care providers in front of an audience. Participants demonstrate communication, teamwork, clinical management, and problem-solving skills. Upon completion, judges debrief participants’ clinical actions and team dynamics. Purpose: The Society for Emergency Medicine in Singapore hosted the inaugural SimWars in 2014. This study investigated whether SimWars was effective in teaching emergency medicine staff, explored how the competitive nature of SimWars affected the performance and learning of participants, and identified strategies to implement SimWars effectively in Singapore. Methods: A descriptive qualitative design was selected owing to the exploratory nature of the questions. Thirteen SimWars participants, six audiences, and three judges participated in the study. Results: (1) Twenty-one out of 22 considered SimWars useful for learning; (2) 14 out of 19 agreed that SimWars closely resemble clinical practice compared to clinical practice; (3) 16 out of 19 agreed that competition induced stress from participants and enhanced performance; (4) 16 out of 22 said SimWars was psychologically safe; (5) 18 said the team worked well together; (6) 19 said that debriefing helped them to improve through clarification, discussion, and reflection; debriefing should be personalized, longer, more structured, more detailed, and in a more private manner; (7) 13 said their knowledge and skills on the content areas will change; 21 said what they learned will be transferred to clinical practice; (8) the useful parts of SimWars included practicing under stress, debriefing, teamwork, and critical thinking; and (9) future improvements included avoiding technical problems and providing clear guidelines. Conclusion: Our responders perceived SimWars to be effective for professional development.
Enhancing adherence, subjective well-being and quality of life in patients with schizophrenia: which role for long-acting risperidone?
Authors: Niolu Cinzia , Bianciardi Emanuela , Di Lorenzo Giorgio , Marchetta Claudia , Barone Ylenia , Sterbini Nicoletta , Ribolsi Michele , Reggiardo Giorgio , Siracusano Alberto 
Published: August 2015

Aim: This study evaluated adherence to treatment, quality of life and subjective well-being in patients with psychosis treated with long-acting injectable risperidone. Subjects enrolled were part of a larger study where patients were observed in an adherence to treatment program of the University of Rome Tor Vergata. Materials and methods: A total of 27 nonadherent patients (21 men, six women; mean age: 36.1 years; range: 23–63 years) were enrolled. Maximum observational period was 30 months. Results: A total of 12 patients were under treatment for 30 months (44.44%) but only nine had a valid 30-month follow up, while the remaining three patients initially treated at our unit continued long-acting risperidone at their local centre. Reductions of monthly mean values of Scale for the Assessment of Positive Symptoms (SAPS) [repeated measures analysis of variance (rm-ANOVA): p < 0.0001] and Scale for Assessment of Negative Symptoms (SANS) ( p < 0.0001), increase of monthly mean values of Subjective Well-Being Under Neuroleptic Treatment Scale (SWN) ( p < 0.0001) and Schizophrenia Quality of Life Scale (S-QoL) ( p < 0.01) were observed. Significant differences with respect to SAPS baseline values from the sixth month, SANS baseline values from the seventh month, SWN baseline values from the eighth month, S-QoL baseline values from the eighteenth month were shown in post hoc tests. Reduction of SAPS mean values was associated with increase of SWN ( p < 0.0001) and S-QoL ( p < 0.0001) mean values as demonstrated by correlation analysis. The same inverse correlation was found between reduction of SANS mean values and increases of SWN ( p < 0.0001) and S-QoL ( p = 0.0001) mean values. Conclusions: Long-term treatment with long-acting risperidone may be associated with improvement to adherence to therapy and quality of life. Patients may show improvement in psychopathological symptoms, subjective well-being and quality of life.
Pharmacy collected medication histories in an observation unit
Authors: Procopio Gabrielle L , Faley Brian , Wynd Michael A , Finefrock Douglas , Kobayashi Michelle , Feldman Joseph 
Published: August 2015

Background: Clear processes to facilitate medication reconciliation in a hospital setting are still undefined. The observation unit allows for a high patient turnover rate, where obtaining accurate medication histories is critical. Objectives: The objective of this study was to assess the ability of pharmacists and student pharmacists to identify discrepancies in medication histories obtained at triage in observation patients. Methods: Pharmacists and student pharmacists obtained a medication history for each patient placed in observation status. Patients were excluded if they were unable to provide a medication history and family, caregiver, or community pharmacy was also unable to provide the history. A comparison was made between triage and pharmacy collected medication histories to identify discrepancies. Results: A total of 501 medications histories were collected, accounting for 3213 medication records. There were 1176 (37%) matched medication records and 1467 discrepancies identified, including 808 (55%) omissions, 296 (20.2%) wrong frequency, 278 (19%) wrong dose, 51 (3.5%) discontinued, and 34 (2.3%) wrong medication. There was an average of 2.9 discrepancies per patient profile. In all, 76 (15%) of the profiles were matched. The median time to obtain a medication history was 4 min (range: 1–48 min). Conclusion: Pharmacy collected medication histories in an observation unit identify discrepancies that can be reconciled by the interdisciplinary team.
An overview of first-principles calculations of NMR parameters for paramagnetic materials
Authors: Lynch C. I. 
Published: August 2015

Many technologically important materials exhibit paramagnetism, for example, lithium intercalation materials for lithium-ion batteries and platinum nanoparticles for catalysis. In order to study their properties, for example, their electron transport properties or catalytic efficiency, and hence tailor them to specific engineering applications, information on their structure and bonding needs to be acquired. Solid state nuclear magnetic resonance (NMR) is an excellent experimental method for achieving this; however, the resulting spectra are often difficult to interpret. Calculations based on quantum mechanics therefore provide an invaluable aid for decoding these experimental spectra. The dominant interaction in paramagnetic materials is the hyperfine interaction. This is the interaction between the spin of a nucleus and the spin of an unpaired electron. The hyperfine interaction affects the appearance of NMR spectra, both by shifting the frequencies at which resonance occurs and by removing degeneracies so that a single resonance frequency splits into several frequencies. This review examines the methods and current limitations for calculating hyperfine interaction parameters, placing this in the context of experimental NMR investigations for lithium intercalation materials and platinum nanoparticles. In this way, the importance of developing increasingly accurate methods for calculating hyperfine parameters is illustrated.
Physician report cards and rankings yield long-lasting hand hygiene compliance exceeding 90 %
Authors: Reich John Adam , Goodstein Monica E. , Callahan Susan E. , Callahan Kathleen M. , Crossley Lindsay W. , Doron Shira I. , Snydman David R. , Nasraway Stanley A. 
Published: August 2015

Abstract
Introduction
Hand hygiene is an effective, low-cost intervention that prevents the spread of multidrug-resistant bacteria. Despite mandatory education and reminders, compliance by physicians in our hospital remained stubbornly low. Our objective was to study whether surveillance by our unit coordinator (secretary) paired with regular feedback to chiefs of service would increase physician hand hygiene compliance in the ICU.

Method
The ICU unit coordinator was trained to observe and measure hand hygiene compliance. Data were collected on hand hygiene compliance at room entry and exit for 9 months. Percentage compliance for each medical and surgical subspecialty was reported to chiefs of service at the end of each month. Comparative rankings by service were widely distributed throughout the physician organization and the medical center.

Results
The hand hygiene compliance rate among physicians increased from 65.1 % to 91.6 % during the study period (p <0.0001). More importantly in the succeeding 24 months after study completion, physician hand hygiene compliance remained >90 % in every month.

Conclusions
Physician hand hygiene compliance increased as a consequence of the surveillance conducted by a full-time ICU team member, leading to a highly significant increase in the number of observations. In turn, this allowed for specific comparative monthly feedback to individual chiefs of service. Over the next 2 years after the study ended, these gains were sustained, suggesting an enduring culture change in physician behavior.
Vitamin D deficiency in chronic inflammatory rheumatic diseases: results of the cardiovascular in rheumatology [CARMA] study
Authors: Urruticoechea-Arana Ana , Martín-Martínez María A. , Castañeda Santos , Piedra Carlos A. Sanchez , González-Juanatey Carlos , Llorca Javier , Díaz-Gonzalez Federico , González-Gay Miguel A. ,   on behalf of the CARMA Project Collaborative Group
Published: August 2015

Abstract
Introduction
The aim was to study the association between 25-hydroxyvitamin D (25(OH)D) levels and the clinical characteristics of patients with chronic inflammatory rheumatic diseases (CIRD).

Methods
We studied a cross-section from the baseline visit of the CARMA project (CARdiovascular in rheuMAtology), a 10-year prospective study evaluating the risk of cardiovascular events in rheumatoid arthritis (RA), ankylosing spondylitis (AS) and psoriatic arthritis (PsA) patients, and non-CIRD patients who attended rheumatology outpatient clinics from 67 hospitals in Spain. Non-CIRD group was frequency matched by age with the joint distribution of the three CIRD groups included in the study. 25(OH)D deficiency was defined if 25(OH)D vitamin levels were < 20 ng/ml.

Results
2.234 patients (775 RA, 738 AS and 721 PsA) and 677 non-CIRD subjects were assessed. The median (p25-p75) 25(OH)D levels were: 20.4 (14.4-29.2) ng/ml in RA, 20.9 (13.1-29.0) in AS, 20.0 (14.0-28.8) in PsA, and 24.8 (18.4-32.6) ng/ml in non-CIRD patients. We detected 25(OH)D deficiency in 40.5 % RA, 39.7 % AS, 40.9 % PsA and 26.7 % non-CIRD controls (p < 0.001). A statistically significant positive association between RA and 25(OH)D deficiency was found (adjusted (adj.) OR = 1.46; 95 % CI = 1.09-1.96); p = 0.012. This positive association did not reach statistical significance for AS (adj. OR 1.23; 95 % CI = 0.85-1.80) and PsA (adj. OR 1.32; 95 % CI = 0.94-1.84). When the parameters of disease activity, severity or functional impairment were assessed, a marginally significant association between 25(OH)D deficiency and ACPA positivity in RA patients (adj. OR = 1.45; 95 % CI = 0.99-2.12; p = 0.056), and between 25(OH)D deficiency and BASFI in AS patients (adj. OR = 1.08; 95 % CI = 0.99-1.17); p = 0.07) was also found.

Conclusions
Patients with RA show an increased risk of having 25(OH)D deficiency compared to non-CIRD controls.
About MFL Technology Application for Ship Plating Corrosion Damages Detection
Authors: Сясько  , Syasko Vladimir 
Published: August 2015

Introduction. The article considers matters on ensuring entire nondestructive inspection of ship plating residual thickness with the use of Magnetic Flux Leakage (MFL) technique. The work aim is optimization of measuring transducers magnetic system parameters in order to guarantee the required sensitivity level at the plating thickness range of 3÷16 mm.
Method. Physical and mathematical models of transducers were developed; the finite-element method was used for formulating the optimization criteria.
Results. Dependences have been obtained that link tested thicknesses range and measurement error with magnetic system geometry and magnetization modes. The influence of nuisance parameters has also been studied.
Conclusion. A set of measuring transducers for entire ship plating residual thickness measurements as well as techniques for adjustment and testing for pitting and planar corrosion detection have been developed as a result of this work.
Special Report on ISAHP2011
Authors: De Felice Fabio 
Published: August 2015

<p>I am proud and honored to contribute to this issue of the International Journal on the Analytic Hierarchy Process. It is the first issue since the International Symposium on the Analytic Hierarchy Process 2011 (ISAHP 2011) was held in Sorrento (Naples, ITALY) from June 15-­18, 2011...</p><p>http://dx.doi.org/10.13033/ijahp.v3i2.125</p>
USING ANP TO DESIGN A LIVING SYSTEM LIKE BALANCED OPERATING MODEL FOR INTANGIBLE SERVICES
Authors: Minzoni Angela , Mounoud Eléonore , Zahraei Majid Fathi 
Published: August 2015

<div class="page" title="Page 1"><div class="layoutArea"><div class="column"><p>There is no need to present another ANP-based approach for weighting criteria within decision making contexts. Academic literature in disciplines like economics, engineering, political sciences, statistics or mathematics testify to the broadness of topics, situations and cultures where the method’s value has been proven. From supply planning or road mapping to monitoring, from crisis management or banking crime to rural water supply, decision makers –both in governments or firms- have implemented this method on the five continents.</p><p> </p><p>However, the method has been used less in areas beyond decision making. For example, in the field of innovation or organisational design, it can be expected that ANP facilitates the formulation of a suitable dynamic to combine the complex links of experts’ representations of the system under study. We advance the hypothesis that the ANP method’s friendliness to rough data, and ability to combine tangible and intangible information can be useful for providing the relevant interactions for living systems like modelling which is at the centre of the cross disciplinary creativity needed to design innovative and balanced operating models. In this context “operating models” shall be understood as the descriptions of how organizations operate across processes, people and technology in order to accomplish their functions.</p></div></div></div>
‘X marks the spot’: Urban dystopia, slum voyeurism and failures of identity in District X
Authors: Lund Martin 
Published: August 2015

Abstract
This article studies the ‘imaginative mapping’ of a real-world neighbourhood in one comic book series: lower Manhattan’s Alphabet City in writer David Hine and artists David Yardin and Lan Medina’s District X (July 2004–January 2006). In contrast to a long-standing claim to ‘realism’ in Marvel’s use of New York City, this article argues that the real Alphabet City – at the time a contested and rapidly gentrifying neighbourhood – is nowhere to be found in District X, replaced by a voyeuristic fabrication, a sensationalistic node of concentration for middle-class fears about urban decline and blight amid prosperity and contemporary discourses about drugs, crime and homelessness that reproduces long-standing cultural representations of the neighbourhood as different and inferior. In doing so, the series polices a boundary of identity, empathy and imagination and tells readers that force in favour of clearing out radical difference in the neighbourhood and making it into a space fit for ‘normal’ people is natural, rational and logical and in the best interest even of those who might be displaced by gentrification, disproportionately incarcerated in the name of ‘law and order’, or put at risk of their lives in dangerous shelters.
Quasi-static behavior of notched Ti-6Al-4V specimens in water-methanol solution
Authors: Baragetti Sergio , Gerosa Riccardo , Villa Francesco 
Published: August 2015

Abstract
The adoption of Ti-6Al-4V titanium alloy is widespread in advanced engineering fields, such as the aerospace, automotive, and maritime sectors, due to its remarkable mechanical characteristics and proven corrosion resistance. However, literature studies and field failures have underlined that the Ti-6Al-4V is susceptible to the stress corrosion cracking (SCC) and the corrosion fatigue phenomena in methanol-water solutions. Although several studies focused on the SCC behavior of this particular titanium alloy, recent corrosion fatigue experiments (R=0.1) on Ti-6Al-4V specimens in a water-methanol environment have highlighted a sensible decrease in maximum applied stress of up to 50% and a high sensitivity even to low methanol concentrations. In the present work, an experimental quasi-static SCC test campaign in water-methanol mixture at different concentrations has been conducted on flat dogbone Ti-6Al-4V specimens. The results have been compared with recent corrosion fatigue experiments to characterize the different damage mechanisms at play and decouple mechanical and chemical driving forces. The micromechanical behavior of the material has been analyzed, highlighting the role of the microstructure in the SCC mechanism. Failure surfaces have been investigated with scanning electron and optical microscopy.
Association of ABCB1, ABCC5 and xanthine oxidase genetic polymorphisms with methotrexate adverse reactions in Mexican pediatric patients with ALL
Authors: Zaruma-Torres Fausto , Lares-Asseff Ismael , Reyes-Espinoza Aarón , Loera-Castañeda Verónica , Chairez-Hernández Isaías , Sosa-Macías Martha , Galaviz-Hernández Carlos , Almanza-Reyes Horacio 
Published: August 2015

Abstract

Background: Acute lymphoblastic leukemia (ALL) is one of the most frequent oncological disorders in pediatric populations. To date, the drug of choice for the treatment of ALL is methotrexate, a drug associated with a high risk of adverse reactions (ADRs). The xanthine oxidase (XO) polymorphisms, 1936A>G and 2107A>G, as well as the polymorphic variants derived from ATP-binding cassette transporter gene subfamilies, ABCB1 and ABCC5, of drug resistant codifying genes, are implicated as precursors of drug-related neurologic, hepatic, and renal toxicities. Our aim was to determine whether the mentioned polymorphisms are risk or protective factors for the development of adverse reactions by methotrexate in our pediatric population with ALL.

Methods: A total of 35 Mexican children from Centro Estatal de Cancerología-Durango, Mexico, with ALL and the previously noted polymorphisms as determined qPCR were studied. At the same time, a 12-month drug monitoring program was conducted in accordance with WHO-PAHO guidelines for pharmacovigilance.

Results: The ABCB11936A>G and 2107A>G and ABCC5 3414+434A>C polymorphisms were not associated with methotrexate ADRs. Single nucleotide polymorphisms (SNPs) of ABCB1 1236C>T (OR 0.19, 95% CI: 0.03–0.9, p<0.05) and ABCC5 3933+313T>C (OR 0.12, 95% CI: 0.027–0.58, p<0.05) were associated with methotrexate ADRs.

Conclusions: SNPs 1236C>T of ABCB1 and ABCC5 3933+313T>C are not associated with the development of typical ADRs by methotrexate, rather, they showed a protective factor for myelosuppression in the studied sick population.
Melanoma differentiation-associated gene 5 is involved in the induction of stress granules and autophagy by protonophore CCCP
Authors: Xu Feng , Li Xiaobo , Zhang Peifen , Xia Jun , Wang Yi , Yang Chao , Gao Huixin , Zhou Shili , Zhang Ping 
Published: August 2015

Abstract
The eukaryotic cell has evolved a variety of stress responses against external stimuli, such as innate immunity, the formation of stress granules (SGs), and autophagy. We previously demonstrated that the innate immune adaptor IFN-β promoter stimulator 1 (IPS-1) plays an essential role in the formation of dsRNA-induced SGs, indicating a connection between SG formation and innate immunity. In this study, it was further demonstrated that melanoma differentiation-associated gene 5 (MDA5), an innate immune sensor, is involved in SG formation induced by carbonyl cyanide m-chlorophenylhydrazone (CCCP), a mitochondrial protonophore. MDA5 knockdown had no significant impact on the phosphorylation of eukaryotic translation initiation factor 2α (eIF2α) triggered by CCCP, and MDA5 itself was not recruited to SGs, suggesting that the regulation of MDA5 in the SG response occurs downstream of eIF2α. Furthermore, the depletion of MDA5 or G3BP1 led to reduced autophagy in CCCP-stimulated cells, implying that the regulatory effect of MDA5 with respect to autophagy depends on its role in SG formation. This study uncovered an unexpected role of the innate immune protein MDA5 in SG formation and autophagy triggered by the protonophore CCCP, further supporting a correlation between different stress responses.
Antenatal risk factors for symptomatic congenital CMV disease following primary maternal CMV infection
Authors: Hadar Eran , Salzer Liat , Dorfman Elizabeta , Amir Jacob , Pardo Joseph 
Published: August 2015

AbstractThis study aimed to evaluate antenatal risk factors associated with symptomatic congenital cytomegalovirus (CMV) disease, followingThis study included a retrospective cohort of 155 neonates with congenital CMV infection, following primary maternal CMV infection during pregnancy, and were divided to symptomatic (n=95) and asymptomatic (n=60) newborns.Young maternal age (29.1±5.12 vs. 31.6±5.36 years, P=0.005), high risk occupation for viral exposure (20.0% vs. 11.7%, P=0.04), CMV IgG seroconversion at diagnosis (83.1% vs. 63.3%, P=0.005) and abnormal fetal MRI (11.6% vs. 0%, P=0.003) were found to be prognostic risk factors associated with symptomatic CMV disease of the newborn. Maternal febrile illness at diagnosis, IgG avidity, US findings and the timing of maternal infection were not associated with the occurrence of neonatal symptoms.Knowledge of the reported risk factors may assist in counseling parents with intra uterine CMV infection.
On the occurrences of anaphoric bare NPs in Japanese
Authors: Nemoto Naoko 
Published: August 2015

AbstractIt is known that bare NPs can be interpreted as an indefinite description or a definite description in Japanese. A question arises as to whether a bare NP in Japanese can always obtain an intended anaphoric definite reading from the previous context. The present work attempts to answer this question. More specifically, we will explore the occurrences and nonoccurrences of anaphoric definite bare NPs in terms of the Givenness Hierarchy of
Pathological Intoxication and Alcohol Idiosyncratic Intoxication—Part II: Legal Aspects
Authors: Perr IN 
Published: August 2015

Abstract
The law does not generally allow alcohol intoxication as a defense in a criminal matter. Among the exceptions may be pathological intoxication, or PI, or its current psychiatric correlate, alcohol idiosyncratic intoxication (AII). Because of the lack of specificity in the medical concept and the varying approaches by different authors, careful analysis and adherence to current standards are necessary. Relevant laws, particularly that of the model penal code, are reviewed, as are three cases which demonstrate the issues involved. Actual testimony is presented to illustrate possible misuse or inappropriate use of the concept.