bluuebunny/crossref_metadata_2025_split huggingface dataset:
Chelated forms of trace elements improve antioxidant properties and nodulation potential of soybean-Bradyrhizobium symbiosis under insufficient water conditions
Authors: Nyzhnyk T. P. , Kots S. Y. , Pukhtaievych P. Р. , Kots T. A. , Vegera L. V. 
Published: July 2024

The development of new nanotechnological approaches and the appearance of preparations with low concentrations of microelements can serve as a basis for promising solutions aimed at increasing stress-protective properties and tolerance to the adverse factors effects. The aim of the study is to show the effectiveness of seed inoculation with nodule bacteria modified by chelate forms of trace elements germanium, ferrum and molybdenum to stimulate antioxidant properties and improve the functioning of the Glycine max (L.) Merr. – Bradyrhizobium symbiosis in insufficient water supply conditions. For this, the symbiotic systems of soybean with active virulent Bradyrhizobium japonicum B1-20 were used with the addition of chelated forms of ferrum, germanium and molybdenum in a dilution of 1:1000 to the culture medium. The chelator was citric acid. At the phenological stages during active nitrogen fixation by soybeans, two models of plant watering regimes were created ̶ optimal at the level of 60% of the full field capacity and insufficient/water stress at the level of 30% of the full field capacity. Microbiological, physiological, and biochemical methods of plant testing were used. It was found that the addition of rhizobia, chelated forms of germanium or ferrum to the culture medium, induces an increase in the antioxidant properties of plants by activating the key enzymatic complexes of superoxide dismutase and ascorbate peroxidase in soybean nodules and leaves under water stress. The use of chelated forms of ferrum or germanium led to the stimulation of the Bradyrhizobium nodulation potential, which was accompanied by the optimization of the water status and growth processes of soybean plants in insufficient moisture supply conditions. It was shown that inoculation with rhizobia containing chelated forms of molybdenum induced soybean plants sensitive to water deficit, as evidenced by an unstable reaction of enzyme activity, decrease or increase, in nodules and leaves. It inhibits nodulation processes on soybean roots and at the same time disrupts the water status of plants with insufficient water supply. It was concluded that the addition of chelated forms of germanium or ferrum to the rhizobia culture medium is a promising solution for stimulating the protective antioxidant properties of soybeans, which helps to optimize the physiological state of plants under insufficient water conditions.
STATISTICAL CONVERGENCE OF DOUBLE SEQUENCES IN NEUTROSOPHIC 2-NORMED SPACES
Authors: Mondal Rahul , Hossain Nesar 
Published: July 2024

In this paper, we have studied the notion of statistical convergence for double sequences in neutrosophic 2-normed spaces. Also, we have defined statistically Cauchy double sequences and statistically completeness for double sequences and investigated some interesting results in connection with neutrosophic 2-normed space.
ON \(G\)-VERTEX-TRANSITIVE COVERS OF COMPLETE GRAPHS HAVING AT MOST TWO \(G\)-ORBITS ON THE ARC SET
Authors: Tsiovkina Ludmila Yu. 
Published: July 2024

We investigate abelian (in the sense of Godsil and Hensel) distance-regular covers of complete graphs with the following property: there is a vertex-transitive group of automorphisms of the cover which possesses at most two orbits in the induced action on its arc set. We focus on covers whose parameters belong to some known infinite series of feasible parameters. We also complete the classification of arc-transitive covers with a non-solvable automorphism group and show that the automorphism group of any unknown edge-transitive cover induces a one-dimensional affine permutation group on the set of its antipodal classes.
Runcofa and the Inner Temple in the Alfredian Metres of Boethius
Authors: Solomonik-Pankrashova Tatyana 
Published: July 2024

This article will argue that the author of the Old English Metres of Boethius enhanced the mystical themes of the B text (the prose text) in the light of ideas articulated in John Scottus Eriugena’s Periphyseon, permeated by the Greek thought of Gregory of Nyssa, pseudo-Dionysius and Maximus the Confessor. In particular, it presents a mystical reading of the unique poetic compound runcofa, “the mystery chamber,” which appears in Metre 22 paired with incofa, “an inner chamber,” proposing that these terms bear the mark of what Eriugena terms adyta, “the inner sanctuary,” the dwelling place of “obscurissimas tenebras excellentissimae lucis,” “the uttermost darkness of the most excellent Light” (Eriugena, Periphyseon V, 983B). Interpreting Metre 22 as a theophany, the article focuses on Mod’s descent into the innermost heart— runcofa—the place of mystical union.
Síndrome de Wolf-Hirschhorn y facomatosis pigmento vascular: ¿coincidencia o asociación? Reporte de caso
Authors: González García Sofía Sarai , Lomelí Valdez Rodrigo , Martínez García Lorena Sofía , García Verónica Méndez , Orozco Covarrubias María de la Luz , Cerda Rodríguez Raúl Arturo , Ruiz García Rosa María 
Published: July 2024

ANTECEDENTES: El síndrome de Wolf-Hirschhorn (SWH) es una cromosomopatía que se produce por una deleción en la región distal del brazo corto del cromosoma 4 (4p16.3). Se caracteriza por facies en “casco de guerrero griego”, retraso del crecimiento intrauterino y postnatal, retraso global del neurodesarrollo, epilepsia y alteraciones cardiacas. La facomatosis pigmento vascular (FPV) es un síndrome caracterizado por la asociación de malformaciones vasculares capilares y lesiones melanocíticas cutáneas congénitas con o sin alteraciones sistémicas.
CASO CLÍNICO: Recién nacido femenino de 37 semanas de gestación, que nació por cesárea por restricción de crecimiento intrauterino tipo I y pérdida de bienestar fetal. Se realizó el diagnóstico prenatal de SWH mediante amplificación de sondas dependiente de ligandos múltiples (MLPA) y al nacimiento mediante hibridación con fluorescencia in situ (FISH). Al nacimiento se corroboró la restricción de crecimiento intrauterino (menor al percentil 3), facies característica, alteraciones cardíacas y neurológicas y la presencia de melanocitosis dérmica y malformaciones vasculares capilares cutáneas.
CONCLUSIÓN: Se documenta por primera vez la presencia de SWH y de FPV en una paciente. El estudio genético en síndromes complejos es fundamental para entender su etiopatogenia.
Morphological and Molecular Identification of Oryctes (Coleoptera: Scarabaeidae) Collected from Date Palm Plantations in Algeria1
Authors: Rais Sana , Saadi Inesse , Kontschán Jenő , Boumaraf Belkacem , Guimeur Kamel , Bouazzi Habib 
Published: July 2024

Abstract
Light traps operated from May 2022 to August 2023 collected Oryctes beetles (Coleoptera: Scarabaeidae) in date palm (Phoenix dactylifera L.) plantations in El Oued, Algeria. Morphological examination of 105 adult Oryctes specimens collected from the plantations revealed them to be Oryctes agamemnon arabicus (Fairmaire). Molecular identification, using the cytochrome oxidase c subunit I (COI) marker, confirmed those identifications. Notably, MASH analysis revealed differing degrees of genetic similarity, suggesting nuanced genetic diversity within the population. Utilizing Kraken2 software and the COI database from the National Center for Biotechnology Information, we also determined a high classification rate of approximately 99% of reads for all samples, reinforcing the identity of the specimens as O. agamemnon. These results help advance taxonomic knowledge of the insect fauna of the region as well as supporting environmental conservation initiatives.
Review and Current Status of Systena frontalis (Coleoptera: Chrysomelidae): An Insect Pest Associated with Nursery Production Systems1
Authors: Herrick Nathan J. , Cloyd Raymond A. 
Published: July 2024

Abstract
Systena frontalis (F.) (Coleoptera: Chrysomelidae) is an insect pest of nursery production systems throughout the Midwest, Southeast, and Northeast regions of the United States. The original scientific name was Galleruca frontalis F. before reclassification of the genus to Systena. There is minimal information in the scientific literature providing evidence that S. frontalis is native or an introduced species. In addition, the overwintering life stage is unknown. However, records indicate that S. frontalis is native to North America based on reports of this beetle being found in 5 provinces of Canada and 31 states in the United States. Records also indicate that the adult may be the overwintering life stage. Current management strategies implemented to reduce feeding damage caused by S. frontalis adults to container-grown nursery plants are associated with foliar spray applications of contact insecticides. However, applying contact insecticides to plant material in nursery production systems is labor intensive and not cost efficient. Application of systemic insecticides to the growing medium is a management strategy that nursery producers can use to reduce feeding damage caused by S. frontalis adults. Research demonstrates that the systemic insecticides dinotefuran and thiamethoxam protect container-grown nursery plants 45 d after application. Therefore, based on empirical, scientific-based research, applying systemic insecticides before S. frontalis adults are active provides practical and cost-effective plant protection from adult feeding damage during the growing season, thereby allowing nursery producers to grow, market, and sell container-grown nursery plants.
The Formation and Pressure-Bearing Characteristics of Plugging Layers in Hydraulic Fracture: A Visualization Experimental Study
Authors: Zhan Li , Qian Bin , Guo Jianchun , Guan Bin , Ren Yong , He Le , Liu Yuxuan , Lu Qianli 
Published: July 2024

Summary
Temporary plugging and diversion fracturing (TPDF) is an important means for improving the artificial fracture complexity in shale gas reservoirs. At present, most scholars’ studies on TPDF mainly focus on the formation conditions of the plugging layer in a horizontal fracture and the fracture propagation behavior after the plugging layer is formed. However, there is a lack of thorough study on the formation and pressure-bearing characteristics of the plugging layer in vertical fracture.
For this paper, we conducted a plugging experiment using temporary plugging particles in a hydraulic fracture by use of a visualization hydraulic fracture experimental device to analyze the formation and pressure-bearing characteristics of plugging layers. The research results show that (1) when the ratio of temporary plugging particle diameter to fracture width (d/w) becomes larger, the fluid viscosity and injection rate have less influence on the formation of the plugging layer, and the concentration of temporary plugging particles required to form the plugging layer decreases. When d/w is equal to 0.45, the plugging layer has difficulty forming if the fluid viscosity is greater than 3 mPa·s or the mass concentration of temporary plugging particles is less than 20 kg/m3. If d/w is equal to 0.60, the plugging layer has difficulty forming when the concentration is less than 10 kg/m3. When d/w is equal to 0.75, a plugging layer forms when the concentration is 2.5 kg/m3, and the formation is not affected by the fluid viscosity and injection rate. (2) A smaller d/w, higher carrier fluid viscosity and injection rate, or lower temporary plugging particle concentration all lead to more pronounced fluctuation of the fracture flow channels at the location where the plugging layer is formed. (3) If the plugging layer can form, it is denser and has stronger plugging ability when the temporary plugging particle diameter is smaller and fluid viscosity and injection rate are larger. (4) Due to different lengths and d/w, the plugging layer can be divided into three types according to its morphological change characteristics after pressure-bearing: failure-unstable, locally-damaged, and stable-unchanged plugging layer. To improve the probability of forming the plugging layer with higher stability, the fluid with a viscosity of 3 mPa·s, in which is a temporary plugging particle with a d/w of 0.75, is recommended to plug the hydraulic fractures under an injection rate of 0.65 m3/min.
Gene expression in normal-weight mice offspring from parents on Western Diets suggests altered risk for obesity and metabolic disease
Authors: Czechowski Paul , Hoffmann Anne , Dommel Sebastian , Jaïs Alexander , Blüher Matthias , Klöting Nora 
Published: July 2024

Abstract

The influence of parental obesity on a child's likelihood of becoming an obese adult remains uncertain. Concurrently, the Western diet is deemed a significant factor in obesity prevalence. Hence, we investigated how parents' Western diet impacts offspring's obesity risk. Recent rodent studies indicate males are more susceptible to inheriting obesity than females. Therefore, we focused on whether exposure to maternal, paternal, or parental obesogenic diet during early development stages might program long-term overweight in males.
We randomly assigned three-week-old C57BL6/N mice to two diet groups: a Western diet (WD) and a control diet (CD). From 6 to 14 weeks of age, mice in both groups received their assigned diets. Adult females from both diet groups were mated with males from both diet groups, resulting in four breeding cage combinations: CD/CD (parental control diet), CD/WD (maternal Western diet), WD/CD (paternal Western diet), and WD/WD (parental Western diet).

We analyzed weight gain trajectories of parental (P) and filial (F1) individuals based on animal sex, litter size, and parental diets. F1 transcriptome assays were conducted on four tissues: interscapular brown adipose (IBAT), epididymal white adipose (EWAT), subcutaneous inguinal white adipose (INGWAT), and liver (LIV) of male offspring. q-mode PCA was used to evaluate the effects of sex, litter size, and parental diet on the transcriptomes. We then examined the influence of parental dietary combinations, focusing on 27 obesity-related genes to describe transcriptome changes. Differentially expressed genes (DEGs) between dietary contrasts were identified and described using Gene Ontology terms.

Filial weight gain was primarily influenced by sex and litter size, with no significant effect from parental diet. Transcriptome data showed no clustering by sex or litter size. Most DEGs (FDR-adjusted p < 0.05, log2-fold change = 1) were found between offspring of parents on the Western diet (WD/WD) and control diet (CD/CD): 46 in INGWAT, 44 in BAT, 33 in LIV, and 11 in EWAT. GO terms for these genes were linked to regulatory processes associated with high energy intake and Western diets, such as inflammation and cell death in INGWAT, regulatory processes counteracting weight gain and inflammation in IBAT and EWAT, and increased cellular stress in LIV.

We provide new transcriptomic support for the hypothesis that having two obese parents, rather than having only one obese parent, alters the risks of obesity and metabolic disease, likely for the worse.
Technological mapping of plant-based patents for treating bovine mastitis
Authors: Vidal Camila Silva , de Carvalho Gustavo Henrique Santos , de Assis Maria Cristina , Angeli Renata , Victório Cristiane Pimentel 
Published: July 2024

Abstract

Bovine mastitis costs the world’s economy an estimated USD 19.7–32 billion annually. Plant-based products have been used as alternative treatments with advantages such as minimal side effects, and no studies have reported the formation of resistant microorganisms. To identify these plant-based products, this study performed a technological mapping of patent applications. We applied the terms ‘Mastitis AND Extract’ and ‘Bovine OR Plant OR Livestock OR Cow’ to the Espacenet database to find relevant patents. Following this, we applied the same terms to the International Patent Classification (IPC) to categorize patents according to their technological area of use. We found that private companies were the main applicants, among which Chinese companies comprised the majority (52%) and that Taraxarum was the most cited plant in patents. The main applicant was the Lanzhou Institute with seven patents. The most recurrent IPC was A61k36, which refers to medicinal preparations based on algae, lichens, fungi, or plants. From 2000 onwards, the number of patent filings increased, according to the survey, and in 2015, 31 relevant patent applications were filed. Based on this patent survey, we gained a panoramic view of the plant-based.
Therapeutic Potential of Desmodium styracifolium Polysaccharide in Attenuating Nano-Calcium Oxalate Induced Renal Injury and Epithelial-to-Mesenchymal Transition
Authors: Sun Xin-Yuan , Yu Bang-Xian , Huang Ling-Hong , Zhang Quan , Sun Dong-Lin , Liu Yang , Zeng Guo-Hua , Liu Yong-Da 
Published: July 2024

Abstract

Calcium salt deposition in the kidney induces epithelial-to-mesenchymal transition (EMT) in renal tubular epithelial cells, which is the pathological basis for the progression to renal fibrosis in patients with renal stones; however, effective drugs to prevent and treat this disease have not been adequately investigated. In this study, we conducted a comprehensive analysis of fibrosis-related core genes by utilizing bioinformatics on RNA-seq data, along with web database information. Additionally, we designed both in vivo and in vitro experiments to elucidate the mechanisms and signaling pathways through which Desmodium styracifolium polysaccharides (Ds) mitigate renal fibrosis induced by nephrolithiasis. Renal fibrosis is present in both patients afflicted with calcium oxalate (CaOx) stones and in model rats. RNA-seq analysis and network database examination identified TGF-β as a fibrosis-related core gene. Moreover, Ds were found to accumulate in the kidneys of these model rats, effectively reducing crystalline deposits, mitigating renal injury, and alleviating renal fibrosis. Ds effectively attenuated nano-CaOx-induced HK-2 damage and delayed the EMT process by interfering with TGF-β synthesis and secretion and inhibiting the activation of the TGF-β/Smad pathway in vitro. The innovative pharmaceutical Ds may potentially emerge as a novel therapeutic option for the clinical treatment of crystalline renal fibrosis.
Contactless longitudinal monitoring of ageing and dementia-related sleep trajectories in the home
Authors: Soreq Eyal , Kolanko Magdalena , Ravindran Kiran Kumar Guruswamy , Monica Ciro , Revell Victoria , Daniels Sarah , Lai Helen , Golemme Mara , Giovane Martina Del , Walsh Chloe , Wingfield David , Nilforooshan Ramin , Stefanos Marie-Ange , Vittrant Benjamin , De Villele Paul , Dijk Derk-Jan , Sharp David , group CRT 
Published: July 2024

Abstract

Disturbed sleep is common in ageing and dementia, but objectively quantifying it over time is challenging. We validated a contactless under-mattress pressure sensor and developed a data analysis method to assess sleep patterns in the home over long periods. Data from 13,588 individuals (3.7 million nights) from the general population were compared to a dementia cohort of 93 patients (>40,000 nights). Dementia was associated with heterogeneous sleep disturbances primarily characterised by advanced and delayed sleep timing, longer time in bed, and more bed exits. Explainable machine learning was used to derive the Dementia Research Institute Sleep Index (DRI-SI), a digital biomarker quantifying sleep disturbances and their evolution. The DRI-SI can detect the effects of acute clinical events and dementia progression at the individual level. This approach bridges a gap in dementia care by providing a feasible method for monitoring health events, disease progression and dementia risk.
Elschnig’s Pearls as a possible predisposing factor for malignant glaucoma : a case report
Authors: barbé alexandre , momal gabin , cooren alexis , boucher rafael , bachet valentin 
Published: July 2024

Abstract

Background : Malignant glaucoma (MG) is associated with a narrow angle or pseudoexfoliation (PEX)-induced laxity of the zonule. We describe a rare case of MG in a patient with massive Elschnig’s Pearls (EP) causing aqueous misdirection syndrome.
Case presentation :
A 78 years-old female was referred with rapidly progressive left ocular pain with redness, blurred vision of 20/100 and intraocular pressure (IOP) of 60 mmHg. She had undergone cataract surgery 5 years prior without complications, with preoperative diagnosis of moderate capsular PEX syndrome. She was first treated by maximal pressure-lowering drops, intravenous ACETAZOLAMIDE and 10% MANNITOL, 1% ISOPTOPILOCARPINE and a patent laser iridotomy. Despite this, IOP remained high for 3 days. Shallow anterior chamber with angle closure, myopic shift and filling of the posterior chamber by massive EP led us to conclude to an aqueous misdirection syndrome. We then switched 1% ISOPTOPILOCARPINE for 1% ATROPINE and performed a posterior capsulotomy with anterior hyaloidotomy. This rapidly controlled the condition with posterior displacement of intraocular lens (IOL) and fading of the high-IOP associated symptoms.
Conclusions: Identifying malignant glaucoma could be challenging in the absence of immediate surgical circumstances. This is, to our knowledge, the second description of EPassociated with MG. In this case, EP were thought to narrow the irido-corneal angle and to cause a relative pupillary blockage, subsequently triggering aqueous humour misdirection to the vitreous and forward displacement of the iris-IOL diaphragm in the context of moderate PEX-induced zonular laxity.
Epidemiology and Sociodemographic Predictors of Infertility among Women in Ilorin, North-central Nigeria: A 5-Year Retrospective Longitudinal Study
Authors: Odeigah Louis Okebunor , Owolabi Beatrice Omolola , Obalowu Ismaila Aberi , Mutalub Yahkub Babatunde , Agede Olalekan Ayodele , Jimoh Abiodun Akanbi Gafar 
Published: July 2024

Abstract

Background
There are significant variations not only in the incidence and prevalence of infertility but also its sociodemographic determinants among women in Nigeria and globally. The aim of the study was to determine the incidence and prevalence of infertility among women attending the Gynaecology Clinics of the University of Ilorin Teaching Hospital over a 5-year period, and to determine the sociodemographic predictors of the type of infertility among them.
Methods
The study is a 5-year retrospective longitudinal study of women who attended the clinics between 2014–2018. A total of 1163 women’s patient records were eligible for the study. All collected data were analysed using SPSS™ Version 23 statistical software. The incidence rate, and the prevalence per year were calculated and presented. Logistic regression analysis was performed to determine the significant predictors of infertility type among the women.
Results
The calculated incidence rates of infertility during the study period ranged from 2806/ 100,000 women in 2018 to 6918/100,000 women in 2014. The prevalence of infertility during the study period ranged from 6.9% (2014) to 14.4% (2018). The calculated 5-year Cumulative Incidence (or prevalence) for the study period was 14.4%. The burden of secondary infertility cases was twice as that of primary infertility during the study period in total (71.6% vs 28.6%).
Conclusions
This study reported high burden of infertility and especially secondary infertility in the study area. These findings we hope will provide a foundation for further research and the development of targeted interventions to address infertility in the local context.