bluuebunny/crossref_metadata_2025_split huggingface dataset:
Efficacy of black cohosh (Cimicifuga racemosa L.) in treating early symptoms of menopause: a randomized clinical trial
Authors: Mohammad-Alizadeh-Charandabi Sakineh , Shahnazi Mahnaz , Nahaee Jila , Bayatipayan Somaei 
Published: November 2013

Abstract

Background
This study aims to evaluate the efficacy of Black cohosh (Cimicifuga racemosa L.) in treating early menopausal symptoms.

Methods
This randomized, double-blind, placebo-controlled clinical trial was conducted on 84 early post-menopausal participants with Greene climacteric scale (GCS) scores of 15 to 42, who were referred to two public health care centers in Tehran, Iran, in 2011–2012. The participants were randomly allocated into treatment (6.5 mg of dried extract of Black cohosh roots daily) and control (placebo) groups with a ratio of 1:1. The participants took one tablet per day for 8 weeks. The GCS scores were recorded at baseline, and after 4 and 8 weeks of treatment. Data analysis was carried out using a general linear model with repeated measures with SPSS software. The level of significance was set at P < 0.05.

Results
There was no loss to follow-up during the 8 weeks of treatment. The GCS total score (primary outcome) in the treatment group was significantly lower than that in the control group at both week 4 [adjusted mean difference: -7.8 (95% confidence interval: -11.1 to -4.4)] and week 8 [-12.9 (-16.2 to -9.3)]. The treatment group showed significantly more improvement than the control group in all GCS subscale scores (vasomotor, psychiatric, physical, and sexual symptoms; secondary outcomes). The differences between the treatment and control groups at week 8 were significantly higher (P < 0.001) than those at week 4 in terms of the total scores and the vasomotor and psychiatric subscale scores. No side effects were reported.

Conclusions
Black cohosh reduced the GCS total score and all GCS subscale scores (vasomotor, psychiatric, physical, and sexual symptoms) during 4 and 8 weeks of treatment.

Clinical trial registration
This study was approved (Code 9061) by the Ethics Committee of Tabriz University of Medical Sciences and registered at the Iranian Registry of Clinical Trials withIRCT201107186709N4 on 15 January 2012.
MG53′s new identity
Authors: Levy Jennifer R , Campbell Kevin P , Glass David J 
Published: November 2013

Abstract
Mitsugumin 53 (MG53) is a relatively newly identified tripartite motif-containing (TRIM) family muscle-specific E3 ubiquitin ligase that is expressed in skeletal muscle and the heart. It has been postulated to facilitate repair by targeting the site of an injury, and acting as a scaffold for assembly of a repair complex made up of dysferlin, annexin V, caveolin-3, and polymerase I and transcript release factor (PTRF). A recent letter published in Nature by Song et al. proposes an alternate function for MG53: as an E3 ligase that targets the insulin receptor and insulin receptor substrate 1 (IRS1) for degradation, therefore regulating muscle insulin signaling. This work is exciting, as it not only presents a novel role for MG53, but also suggests that muscle insulin signaling has a systemic influence on insulin resistance and the metabolic syndrome.
Sialoadhesin deficiency does not influence the severity of lupus nephritis in New Zealand Black x New Zealand White F1 mice
Authors: Kidder Dana , Richards Hannah E , Lyons Paul A , Crocker Paul R 
Published: November 2013

Abstract
Introduction
Systemic lupus erythematosus (SLE) is a chronic inflammatory condition with multisystem involvement. One of the key features of the disease is the upregulation of type I interferons, resulting in the so-called “interferon signature”. Recent flow cytometric and transcriptomic studies identified Sialoadhesin (Sn, CD169) as an important interferon-induced blood monocyte biomarker in diseased patients. To investigate a potential causative role of Sn in SLE, we generated NZBWF1 (New Zealand Black x New Zealand White F1) mice lacking Sn and compared onset and progression of disease with NZBWF1 expressing normal levels of Sn.

Methods
Sn expression in renal tissues of pre-diseased and diseased NZBWF1 mice was evaluated by Quantitative real time PCR (QPCR) and immunohistochemistry. Sn−/− NZBWF1 mice were generated by speed congenics. Disease severity of Sn+/+ and Sn−/− NZBWF1 mice was assessed by serum immunoassays, flow cytometry, light microscopy and immunohistochemistry.

Results
Renal tissues from proteinuric NZBWF1 mice exhibited a significant upregulation of Sn mRNA and protein expression following disease onset. Further immunohistochemical analysis showed that Sn+ macrophages assumed a distinct periglomerular distribution and, unlike CD68+ macrophages, were not present within the glomeruli. Analysis of disease severity in Sn
−/−
and Sn
+/+
NZBWF1 mice revealed no significant differences in the disease progression between the two groups although Sn-deficient mice showed a more rapid onset of proteinuria.

Conclusions
These data confirm a positive correlation of Sn with disease activity. However, Sn deficiency does not have a significant effect on the severity and progression of lupus nephritis in the NZBWF1 mouse model.
Understanding ‘recovery’
Authors: Roberts Glenn , Boardman Jed 
Published: November 2013

SummaryThe principles of recovery have been supported by UK mental health policy and have been incorporated into policy in several countries worldwide. In this article we examine the ideas, principles and definitions of recovery and their origins. Personal recovery is contrasted with clinical recovery and the nature and development of the recovery movement is outlined. The principal factors influencing personal recovery are hope, control and opportunity. In an accompanying article we discuss the implications of these principles for training and practice.
Young people who cut themselves: can understanding the reasons guide the treatment?
Authors: Wright Barry , Hooke Naomi , Neupert Stephan , Nyein Chan , Ker Suzy 
Published: November 2013

SummaryYoung people who cut themselves may do so for reasons that go beyond diagnosis. Relevant processes include responses to trauma, coping, emotion regulation and cultural identification. Some clinicians regard those who self-harm negatively or consider one therapeutic approach to be suitable for all. This article explores the possible mechanisms involved when young people cut themselves and discusses therapeutic approaches in the light of these. Clinicians and researchers are encouraged to refine, develop and research interventions for young people who self-harm by cutting.
The past and future of delusions research: from the inexplicable to the treatable
Authors: Garety P. A. , Freeman D. 
Published: November 2013

BackgroundProblems with the diagnosis and treatment of schizophrenia have led for a call to change strategy and focus on individual psychotic experiences. In recent years, research on delusions has led the way.AimsTo update our 1999 review of almost 40 studies on delusions.MethodA systematic literature search was conducted of reasoning and affective processes related to delusions.ResultsOver 200 studies were identified. The presence of jumping to conclusions' in individuals with delusions has been substantiated, the theory of mind account has not stood up to subsequent testing, and there is a promising new focus on the ways that affective processes contribute to delusional experience.ConclusionsTheoretical work rendering delusions understandable can be translated into treatment; future clinical trials should focus on individual psychotic experiences as outcomes.
Dye-sensitized Solar Cells Using Supramolecular Porphyrin Arrays Inspired by π-Stacking Structures of Photosynthetic Light-harvesting Complexes
Authors: Fujimoto Junko , Manseki Kazuhiro , Miyaji Hidekazu 
Published: November 2013

Abstract
A slipped cofacial π-stacks of bis(4-carboxyphenyl)bis(1-methylimidazol-2-yl)porphyrinatomagnesium complex can be self-assembled onto TiO2 surface as a light-harvesting core. The porphyrin array allows a more favorable light-to-electricity conversion compared to the monomer analogue in dye-sensitized solar cells.
Continuous Porous Poly(N-isopropylacrylamide) Gels Prepared from a Bicontinuous Microemulsion
Authors: Sakata Kouhei , Taguchi Shun , Uemura Shinobu , Kunitake Masashi , Kawano Shintaro , Nishimi Taisei 
Published: November 2013

Abstract
Continuous porous poly(N-isopropylacrylamide) (pNIPAM) gels were prepared by radical polymerization in a bicontinuous microemulsion (BME) consisting of saline and toluene microphases. The BME gels demonstrated good thermoresponsive water swelling–shrinking performance, exhibiting high speed and large volume change compared with those of homogeneous pNIPAM gels. The BME gels also exhibited swelling with toluene, while the homogeneous pNIPAM gels could not be swollen with toluene.
Requirements Management As An Essential Ingredient Of Communications Management In the Project
Authors: �����  , Gushchin Aleksandr 
Published: November 2013

Special issues of the requirements management process are discussed
based on subject area specialties: from the most formalized (e.g., IT projects),
to the least formalized areas (e.g., design projects). As is shown, the
whole spectrum of apps, related to this subject, can be considered from an
integrated perspective � that is, establishment of effective communication
channel between Customer and Business Analyst (Designer). The features
of communications related to the above-mentioned subject areas are considered
as well as problems of creating such communication channels.
CURRENT TRENDS IN THE STATE EDUCATIONAL POLICY-MAKING IN RUSSIA AND KAZAKHSTAN
Authors: ��������  , Yakovyenko Yevgyeniy , ��������  , Koshchanova Gulash 
Published: November 2013

Social-economic changes in Russia and Kazakhstan are considered as factors
which put forward the urgent need to bring up professionals with appropriate economic expertise. It is emphasized that this goal is of crucial importance for the future of both nations.
The main challenges to the educational system arisen by the current political economic
and social environment factors, are analyzed. In order to develop educational
policy adequate to the present challenges and the declared goal of modernization in
the socio-economic sphere, the authors introduce the concept of instrumentalizing
the process of upbringing professionalism, cognition and creativity in prospective
specialists based on FGOS for higher vocational education (HVE). It is especially
important that the 3rd generation FGOS for the HVE instead of mastering different
kinds of activities is aimed at building labor/professional skills, knowledge and competences,
adequate to the goal of industrial modernization and also in tune with the
social and economic modernization.
Book Reviews
Authors: Rand Graham K. 
Published: November 2013

In Book Reviews, we review an extensive and diverse range of books. They cover theory and applications in operations research, statistics, management science, econometrics, mathematics, computers, and information systems. In addition, we include books in other fields that emphasize technical applications. The editor will be pleased to receive an email from those willing to review a book, with an indication of specific areas of interest. If you are aware of a specific book that you would like to review, or that you think should be reviewed, please contact the editor. The following books are reviewed in this issue of Interfaces, 43(5), September–October, 2013: Optimization for Industrial Problems, Patrick Bangert; Quantitative Problem Solving Methods in the Airline Industry, Cynthia Barnhart and Barry Smith; Introduction to Probability and Stochastic Processes with Applications, Liliana Blanco Castañeda, Viswanathan Arunachalam, and Selvamuthu Dharmaraja; Humanitarian Logistics: Cross-Sector Cooperation in Disaster Relief Management, Alessandra Cozzolino; Enterprise Analytics: Optimize Performance, Process, and Decisions Through Big Data, Thomas H. Davenport; Automation in Warehouse Development, Roelof Hamberg and Jacques Verriet; Data Processing for the AHP/ANP, Kou Gang, Daji Ergu, Yi Peng, and Yong Shi. Modeling with Stochastic Programming, Alan J. King and Stein W. Wallace.
Osteonecrosis of the femoral head
Authors: Issa K. , Pivec R. , Kapadia B. H. , Banerjee S. , Mont M. A. 
Published: November 2013

Symptomatic hip osteonecrosis is a disabling condition with a poorly understood aetiology and pathogenesis. Numerous treatment options for hip osteonecrosis are described, which include non-operative management and joint preserving procedures, as well as total hip replacement (THR). Non-operative or joint preserving treatment may improve outcomes when an early diagnosis is made before the lesion has become too large or there is radiographic evidence of femoral head collapse. The presence of a crescent sign, femoral head flattening, and acetabular involvement indicate a more advanced-stage disease in which joint preserving options are less effective than THR. Since many patients present after disease progression, primary THR is often the only reliable treatment option available. Prior to the 1990s, outcomes of THR for osteonecrosis were poor. However, according to recent reports and systemic reviews, it is encouraging that with the introduction of newer ceramic and/or highly cross-linked polyethylene bearings as well as highly-porous fixation interfaces, THR appears to be a reliable option in the management of end-stage arthritis following hip osteonecrosis in this historically difficult to treat patient population. Cite this article: Bone Joint J 2013;95-B, Supple A:46–50.
Surface replacement conversion
Authors: Su E. P. , Su S. L. 
Published: November 2013

Surface hip replacement (SHR) is generally used in younger, active patients as an alternative conventional total hip replacement in part because of the ability to preserve femoral bone. This major benefit of surface replacement will only hold true if revision procedures of SHRs are found to provide good clinical results. A retrospective review of SHR revisions between 2007 and 2012 was presented, and the type of revision and aetiologies were recorded. There were 55 SHR revisions, of which 27 were in women. At a mean follow-up of 2.3 years (0.72 to 6.4), the mean post-operative Harris hip score (HHS) was 94.8 (66 to 100). Overall 23 were revised for mechanical reasons, nine for impingement, 13 for metallosis, nine for unexplained pain and one for sepsis. Of the type of revision surgery performed, 14 were femoral-only revisions; four were acetabular-only revisions, and 37 were complete revisions. We did not find that clinical scores were significantly different between gender or different types of revisions. However, the mean post-operative HHS was significantly lower in patients revised for unexplained pain compared with patients revised for mechanical reasons (86.9 (66 to 100) versus 99 (96 to 100); p = 0.029). There were two re-revisions for infection in the entire cohort. Based on the overall clinical results, we believe that revision of SHR can have good or excellent results and warrants a continued use of the procedure in selected patients. Close monitoring of these patients facilitates early intervention, as we believe that tissue damage may be related to the duration of an ongoing problem. There should be a low threshold to revise a surface replacement if there is component malposition, rising metal ion levels, or evidence of soft-tissue abnormalities. Cite this article: Bone Joint J 2013;95-B, Supple A:88–91.
Pedagogy of the connected: New media landscapes and the challenges of journalism education
Authors: Ahmad Muhammad Idrees 
Published: November 2013

Abstract
This article proposes a dialogical teaching paradigm based on Paulo Freire’s conception of critical pedagogy. It argues that Web 2.0 technologies are uniquely suitable for such an approach. It moves from theory to prescription. It begins with a survey of the current media landscape and state of journalism. In the light of these, it makes a case for an approach to journalism education in which civic function is complemented by technical proficiency. Based on extant scholarship and the author’s experience as a new media practitioner and educator, the article notes the distinctive features of Web 2.0 technologies that make it particularly amenable to such an approach. It focuses on two specific ones – blogs and wikis – to suggest ways in which the learning experience can be enhanced. But it emphasizes that absent the awareness of journalism’s civic function, technical skills may enhance employability, but they won’t bring professional respect. To compete in a saturated field, journalists will have to show both technical facility and civic responsibility.
Education of journalists on ICTs: Issues and opportunities
Authors: Veglis Andreas 
Published: November 2013

Abstract
This article examines the issue of journalism education on Information Communication Technologies (ICTs). More precisely it investigates the issue of teaching ICTs and in particular of updating and extending existing knowledge and skills. The study proposes the adoption of experiential learning for achieving such an educational goal and describes in detail the journalist’s work process. It also discusses the necessary ICT skills that a journalist must process and presents data from surveys conducted among journalism students and professional journalists in Greece. The article purposes the use of Virtual Learning Environments and Learning Portfolios in order to support journalists’ training on ICTs. Finally it offers recommendations for the deployment of an educational programme that will succeed the described goals.
Gaza Burial, World Press Photo 2013: Between ethics and forensics
Authors: dos Santos Silva Miguel Franquet 
Published: November 2013

Abstract
The controversy surrounding the integrity of Paul Hansen’s award winning World Press Photo of the Year 2013 has moved the debate on ethics and digital images into a new and highly sophisticated technical level. There seems to be no consensus among forensic analyst experts on the question of knowing whether the photograph submitted to 2013 competition is composite or not. In this article, we contend that should ethical principles be preserved from drifting into a set of virtually unlimited technical specifications, the framework for designing and thinking ethical guidelines ruling the use of news images should abandon old conventions and find a new ground where to legitimate photojournalism’s social function.
In vivo, in silico: Ark Codex ± 0 and the vital forms of bookwork
Authors: Malčić Steven 
Published: November 2013

Abstract
This article examines a central aspect of bookishness in the digital age, wherein the coexistence of paper codices along with their electronic counterparts fosters the interaction of life and code, as code is the inscription of life, and life the instantiation of code. Ark Codex ± 0 exemplifies this feedback loop. Ark Codex ± 0 traces the development of biological organisms through scientific notation, language and math, all while illustrating a bloody collage of the biblical myth. The Calamari Press, its vanity publisher, situates itself as a codex-maker in a time of digital production by privileging the book form over the digital file, while simultaneously fostering a print culture through digital paratexts, such as videos of the production process, on its website. While you can purchase the book for $40 on the Calamari site, a pdf of Ark Codex ± 0 is also offered at a ‘pay what you want rate’. Ark Codex ± 0 is a remix with multiple channels of distribution, a text you encounter in multiple ways. This article argues that the new environment of print culture elicits not only the act of reading, but an embodied encounter with the text both in vivo and in silico, the vital forms of bookwork in the digital age.
Nonexistence of positive radial solutions for a problem with singular potential
Authors: Catrina Florin 
Published: November 2013

Abstract.
This article completes the picture in the study of positive radial solutions in the function space

𝒟

1
,
2

(

ℝ
N

)

∩

L
2

(

ℝ
N

,

|
x
|

-
α

d
x

)

∩

L
p

(

ℝ
N

)

${{\mathcal {D}^{1,2}({\mathbb {R}^N}) \cap L^2({{\mathbb {R}^N}, | x |^{-\alpha } dx})\cap L^p({\mathbb {R}^N})}}$

for the equation

-
Δ
u
+

A

|
x
|

α

u
=

u

p
-
1

in

ℝ
N

∖

{
0
}

with

N
≥
3
,
A
>
0
,
α
>
0
,
p
>
2
.

$- \Delta u + \frac{A}{| x |^\alpha } u = u^{p-1} \quad \mbox{in } {\mathbb {R}^N}\setminus \lbrace 0\rbrace \mbox{ with } N\ge 3, A&gt; 0, \alpha &gt; 0, p&gt;2. $

An energy balance identity is employed to prove nonexistence of such solutions in the last remaining open region in the

(
α
,
p
)

${{(\alpha , p)}}$

plane.
Weighted norm inequalities for Schrödinger type operators
Authors: Tang Lin 
Published: November 2013

Abstract
Let

L
=
-
Δ
+
V

${L=-\Delta +V}$

be a Schrödinger
operator, where Δ is the Laplacian operator on ℝ
n
,
while the nonnegative potential V belongs to the reverse Hölder
class. In this paper, we establish the weighted norm inequalities
for some Schrödinger type operators, which include Riesz transforms and fractional integrals and their commutators. These results generalize substantially some well-known results.
A Rheological Model for Cupuassu (Theobroma grandiflorum) Pulp at Different Concentrations and Temperatures
Authors: Chaves Modesto Antonio , Baptistia Fátima , da Silva Jadir Noqueira , Rodrigues Luciano , Viana Arianne Dantas 
Published: November 2013

Abstract
This work was made aiming at studying the best model for the rheological properties of Cupuassu (Theobroma grandiflorum, Schum) pulps with 14 (in nature), 17, 19, 23 and 25°Brix of total soluble solids (TSS) which were measured at 20, 30, 40, 50 and 60°C temperature using a concentric cylinder rheometer. The results were adjusted to the following nine models: Ostwald-de-Waele (power law), Bingham, Casson, Generalized Casson, Heinz–Casson, Herschel–Bulkley, Mizrahi–Berk, Schulmann–Haroske–Reher and Windhab. The parameters of the best model were correlated with pulp temperature and TSS by polynomial regression analysis and were kept in the regression equation only those parameters that contributed more than 1% to the variation of the independent variable. The results indicate that the rheological behavior of Cupuassu pulp in different concentrations and temperatures can be modeled by the Windhab model, although other models can be used in a narrower band of shear stress.
Regularization of the continuation problem for elliptic equations
Authors: Kabanikhin S. I. , Gasimov Y. S. , Nurseitov D. B. , Shishlenin M. A. , Sholpanbaev B. B. , Kasenov S. 
Published: November 2013

Abstract.
We investigate the continuation problem for the elliptic equation. The continuation problem is formulated in operator form . The singular values of the operator A are presented and analyzed for the continuation problem for the Helmholtz equation. Results of numerical experiments are presented.