bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Synthesis, Characterization, and Tuberculostatic Activity of Novel Heterocyclic Compounds Derived from Dimethyl Heteroaroylcarbonohydrazonodithioates.
Authors: Gobis Katarzyna , Foks Henryk , Augustynowicz‐Kopec Ewa , Napiorkowska Agnieszka 
Published: January 2013

AbstractMost of the obtained compounds exhibit low activity in vitro towards M.
ChemInform Abstract: Discovery and Application of Iminotriphenylphosphorane as a Formal Aromatic Primary Amine Protecting Group.
Authors: Delouvrie Benedicte , Germain Herve , Harris Craig S. , Lamorlette Maryannick , Lebraud Honorine , Nguyen Ha Thi Hoang , Noisier Anais , Ouvry Gilles 
Published: January 2013

AbstractAn application of the protection group to the synthesis of benzotriazoles and triazoles is developed and extended to other products such as (VIII) and (X).
ChemInform Abstract: Design, Synthesis and Anticancer Activities of Diaryl Urea Derivatives Bearing N‐Acylhydrazone Moiety.
Authors: Zhang Bei , Zhao Yanfang , Zhai Xin , Wang Lihui , Yang Jingyu , Tan Zehui , Gong Ping 
Published: January 2013

AbstractThe title compounds (I), (II) are screened for their in vitro cytotoxic activities against some human cell lines, A549, MDA‐MB‐231, HL‐60.
ChemInform Abstract: Microwave‐Assisted Synthesis of 3,1‐Benzoxazin‐2‐ones from 3‐Hydroxyoxindoles.
Authors: Suarez‐Castillo Oscar R. , Bautista‐Hernandez Claudia I. , Sanchez‐Zavala Maricruz , Melendez‐Rodriguez Myriam , Sierra‐Zenteno Araceli , Morales‐Rios Martha S. , Joseph‐Nathan Pedro 
Published: January 2013

AbstractTitle compounds (IV), (V) and (VI) are synthesized starting from 3‐hydroxyindoles (I) in a two‐step sequence.
ChemInform Abstract: Design, Synthesis and Anticancer Activity of 4‐Morpholinothieno[3,2‐d]pyrimidine Derivatives Bearing Arylmethylene Hydrazine Moiety.
Authors: Zhu Wufu , Zhai Xin , Fu Qiangqiang , Guo Fei , Bai Mei , Wang Jianqiang , Wang Haiyan , Gong Ping 
Published: January 2013

AbstractMost of the synthesized compounds show moderate to significant cytotoxicity and high selectivity against one or more cell lines.
ChemInform Abstract: Disesquiterpenoid and Sesquiterpenes from the Flos of Chrysanthemum indicum
Authors: Zhou Jing , Wang Jun‐Song , Zhang Yao , Wang Peng‐Ran , Guo Chao , Kong Ling‐Yi 
Published: January 2013

Abstractisolation and structure elucidation of new disesquiterpenoid (I), and sesquiterpenoids (II), (III)
ChemInform Abstract: A New Sphingolipid and Furanocoumarins with Antimicrobial Activity from Ficus exasperata.
Authors: Dongfack Marlise Diane Jiofack , Lallemand Marie‐Christine , Kuete Victor , Mbazoa Celine Djama , Wansi Jean‐Duplex , Trinh‐van‐Dufat Hanh , Michel Sylvie , Wandji Jean 
Published: January 2013

AbstractThe new sphingolipid ficusamide (I) is isolated along with three known furanocoumarins and six other known compounds.
ChemInform Abstract: Alkylphenols from the Roots of Ardisia brevicaulis Induce G1 Arrest and Apoptosis Through Endoplasmic Reticulum Stress Pathway in Human Non‐Small‐Cell Lung Cancer Cells.
Authors: Zhu Guo‐Yuan , Wong Blenda Chi Kwan , Lu Aiping , Bian Zhao‐Xiang , Zhang Ge , Chen Hu‐Biao , Wong Yuen Fan , Fong Wang‐Fun , Yang Zhijun 
Published: January 2013

AbstractTwo new alkylphenol derivatives, ardisiphenol E (Ia) and F (Ib), are isolated along with the known ardisiphenol D.
Parameter Optimization of Activated Carbon Production from Agave sisalana and Punica granatum Peel: Adsorbents for C.I. Reactive Orange 4 Removal from Aqueous Solution
Authors: Senthilkumar Thambiannan , Raghuraman Rajendran , Miranda Lima Rose 
Published: January 2013

AbstractIn the present study, activated carbons were prepared from sisal fiber (Agave sisalana sp.) and pomegranate peel (Punica granatum sp.) using phosphoric acid as the activating agent. Both sisal fiber activated carbon (SFAC) and pomegranate peel activated carbon (PPAC) were characterized using methylene blue number, iodine number, BET surface area, SEM, and FTIR. The BET surface area of the SFAC and PPAC were 885 and 686 m2/g, respectively. The adsorption studies using C.I. Reactive Orange 4 dye on the SFAC and PPAC were carried out. The effects of time, initial adsorbate concentration, pH, and temperature on the adsorption were studied. The isotherm studies were carried and it was found that the Langmuir and Freundlich isotherms fit well for the adsorption of RO 4 on SFAC, while adsorption of RO 4 on PPAC is better represented by the Langmuir and Temkin isotherms. Adsorption kinetics of adsorption was determined using pseudo first order, pseudo second order, Elovich and intraparticle diffusion models and it was found that the adsorption process follows pseudo second order model. Thermodynamics parameters such as changes in free energy (ΔG), enthalpy (ΔH), and entropy (ΔS) were determined by using van't Hoff equation. The positive ΔH value indicates that RO 4 dye adsorption on SFAC and PPAC is endothermic in nature.
Evaluation of Composts from Agricultural Wastes with Fish Pond Sediment as Bulking Agent to Improve Compost Quality
Authors: Karak Tanmoy , Bhattacharyya Pradip , Paul Ranjit Kumar , Das Tapati , Saha Subhrajit K. 
Published: January 2013

AbstractComposts with five different ratios of agricultural wastes, viz. rice straw (RS), wheat straw (WS), potato plant (PP), and mustard stover (MS) were prepared with or without fish pond bottom sediment to investigate the compost maturity and their suitability for field application. The composting process was monitored through the changes in physico‐chemical parameters and germination index (GI) at every 7 days interval of the composting process. All the composts were dark brown and smelled like forest soil within 56 days of composting, which reflected its matured status. On the basis of the physico‐chemical parameters (bulk density: 0.84 g/cm3; pH 7.05; electrical conductivity: 3.52 mS/cm; cation exchange capacity:82.4 cmol/kg; total carbon:321.4 g/kg; total nitrogen: 16.9 g/kg; As: 6.8 mg/kg; Cd: 2.96 mg/kg; Cr: 29.6 mg/kg, Cu: 243.6 mg/kg; Hg: 0.019 mg/kg; Ni: 24.3 mg/kg; Pb: 62.1 mg/kg and Zn: 812 mg/kg) and GI (89–96%), it could be concluded that RS/WS/PP/MS, 1:1:2:1 v/v/v/v with fish pond sediment produced better compost in accordance with the Indian compost standard. Application of a combined randomized block design analysis revealed that there is a significant difference in the responses of the five composts, in relation to the time of composting. Hierarchical clustering algorithm was applied with a view to form homogeneous groups of five different composts on the basis of different physico‐chemical parameters. Therefore, the ratio of waste incorporation is an important decision for composting and addition of pond sediment can improve the quality of compost.
Occurrence of Phthalates in Sewage Sludge from Three Wastewater Treatment Plants in Istanbul, Turkey
Authors: Çifci Deniz İ. , Kınacı Cumali , Arikan Osman A. 
Published: January 2013

AbstractPhthalates are considered priority pollutants because of their potential adverse effects on ecosystems and human health. The objectives of this study were to determine the occurrence of five phthalates (DMP, DEP, DBP, BBP, and DEHP) in sewage sludge and to determine the seasonal variability of these contaminants at three (Bahçeşehir, Paşaköy, and Tuzla) full‐scale municipal and domestic wastewater treatment plants (WWTP) in Istanbul, Turkey. Mass balance was also calculated for DEHP at Tuzla WWTP sludge treatment units. DMP, DEP, DBP, BBP, and DEHP concentrations in sewage sludge ranged from 1.4 to 2.7 mg/kg dry weight (dw), 1.1 to 2.8, 0.6 to 4.6, 2.8 to 6.2, 18 to 490 mg/kg dw, respectively. Phthalate concentrations from the Bahçeşehir and Paşaköy WWTPs met the limit (100 mg/kg dw) of Turkey national sludge regulation and the Europe Union draft of sludge directive for land application, whereas phthalate concentrations from Tuzla WWTP exceeded the maximum permissible concentration. Phthalate concentrations did not show seasonal variations for Bahçeşehir and Paşaköy WWTPs, which receive mainly household wastewater while some fluctuations were observed DEP, DBP, and DEHP at Tuzla WWTP which has a lot of industrial wastewater contribution. The mass balance showed that approximately 17% of DEHP in the primary and secondary sludge was removed by anaerobic digestion, while 43% returned back to the beginning of the WWTP and 40% remained in the dewatered sludge. This study suggests that phthalates in sludge from WWTPs with industrial wastewater contribution may limit the use of sludge for land application.
Transformation of Tobacco with ScMTII Gene‐Enhanced Cadmium and Zinc Accumulation
Authors: Daghan Hatice , Arslan Mehmet , Uygur Veli , Koleli Nurcan 
Published: January 2013

AbstractGenetic transformation is gaining importance for developing plant types suitable to metal accumulate and/or hyperaccumulate. In this study, the transgenic tobacco plant which transferred the ScMTII gene from Saccharomyces cerevisiae to wild type tobacco cultivar Petite Havana (SR1) was grown on soils with low and high cadmium (Cd) and zinc (Zn) concentrations in a growth chamber for 6 weeks and compared to wild type tobacco for Cd and Zn accumulation. Cadmium and Zn accumulations in the transgenic and wild type tobacco plants were increased with the increasing Cd and Zn concentrations. Unlike Zn, the transgenic plant accumulated significantly higher amount of Cd compared to the wild type control plants. Shoot Cd concentrations of transgenic tobacco in higher Cd dosages reached the above the hyperaccumulation threshold value of 100 mg Cd kg−1 in the dry weight (DW). Transgenic tobacco accumulated 354, 400, 372, and 457 mg Cd kg−1 DW, for 10, 20, 40, and 80 mg Cd kg−1 soil treatments, respectively. These values are 3.5–4.5‐fold higher than that of Cd hyperaccumulation threshold value. With 10 mg kg−1 Cd treatment, the bioconcentration factor (BCF) of transgenic tobacco plants for Cd reached up to 35 in which the threshold value for BCF should be at least 10. Our results showed that the transgenic tobacco may be used as a good Cd hyperaccumulator plant and for phytoextraction of Cd contaminated soils, but not for Zn.
Regulating Environmental Factors of Nutrients Release from Wheat Straw Biochar for Sustainable Agriculture
Authors: Wei Linin , Xu Gang , Shao Hongbo , Sun Junna , Chang Scott X. 
Published: January 2013

AbstractOne mechanism by which biochar application enhances soil nutrient availability is through direct nutrients release from biochar. However, factors controlling the release processes are poorly understood. In this study, the effects of pH, biochar to water ratio, temperature, ionic strength, and equilibration time on the release of PO, NO, NH, K+, Na+, Ca2+, and Mg2+ from biochar were evaluated in simulated experiments. The release of PO, K+, Ca2+, and Mg2+ was significantly affected by extraction pH, suggesting that their release from biochar was pH dependent or an H+‐consuming process. Correlation analysis indicated that PO and Ca2+, PO and Mg2+, and Ca2+ and Mg2+ were co‐solubilized with increasing soil acidity. To a lesser extent, the recovery of the nutrients was also affected by the ratio of biochar to water: more nutrients were soluble with more water supply. In contrast, the release of Na was not affected by pH while the concentration increased with decreasing biochar to water ratio. Meanwhile, other factors (temperature, ionic strength, and equilibration time) had less effect on nutrient release from biochar. Under the influence of pH, the patterns of NO and PO release from biochar were different: extractable NO concentration was not affected by the pH but more PO was released in strongly acidic conditions. Our data suggested that P was mainly retained in inorganic forms while N was in organic forms in biochar. We conclude that environmental factors have marked influences on nutrients release from biochar.
Using primary site as a predictor of survival in mantle cell lymphoma
Authors: Ambinder Alexander J. , Shenoy Pareen J. , Nastoupil Loretta J. , Flowers Christopher R. 
Published: January 2013

AbstractBACKGROUND:Mantle cell lymphoma (MCL) is a rare B cell lymphoma that varies in clinical behavior with some patients experiencing aggressive disease with short survival, whereas others have indolent behavior. We examined the association between primary disease site and survival in MCL patients to identify subgroups with distinct characteristics.METHODS:We analyzed the United States Surveillance, Epidemiology and End Results Program database for MCL cases reported from 2000 through 2009. Kaplan‐Meier curves and Cox proportional hazard models were used to estimate the effect of primary site on survival.RESULTS:Among 4477 cases included in our study, 19.6% of patients presented with an extranodal primary site. The most common extranodal primary sites were of the gastrointestinal (GI) tract (7.8%), the head and neck (6.2%), and the hematologic/reticuloendothelial systems (3.6%). Asians/Pacific Islanders were more likely than whites or blacks to have GI tract or head and neck disease (P < .0001 and P = .002, respectively). Advanced disease and B symptoms were less common in those with primary disease of the GI tract or head and neck than in those with primary disease of the lymph nodes (both P < .0001). In a multivariate Cox regression model, patients with primary disease of the GI tract and head and neck had superior survival compared to those with primary disease of the lymph nodes; hazard ratios 0.75 (95% CI = 0.62‐0.90) and 0.68 (95% CI = 0.55‐0.85), respectively.CONCLUSIONS:Primary site of disease may be an important prognostic factor for patients with MCL. Further studies elucidating a biological basis for these differences are needed. Cancer 2013. © 2013 American Cancer Society.
Health care provider communication
Authors: Chochinov Harvey M. , McClement Susan E. , Hack Thomas F. , McKeen Nancy A. , Rach Amanda M. , Gagnon Pierre , Sinclair Shane , Taylor‐Brown Jill 
Published: January 2013

AbstractBACKGROUND:Patients who are facing life‐threatening and life‐limiting cancer almost invariably experience psychological distress. Responding effectively requires therapeutic sensitivity and skill. In this study, we examined therapeutic effectiveness within the setting of cancer‐related distress with the objective of understanding its constituent parts.METHODS:Seventy‐eight experienced psychosocial oncology clinicians from 24 health care centers across Canada were invited to participate in 3 focus groups each. In total, 29 focus groups were held over 2 years, during which clinicians articulated the therapeutic factors deemed most helpful in mitigating patient psychosocial distress. The content of each focus group was summarized into major themes and was reviewed with participants to confirm their accuracy. Upon completion of the focus groups, workshops were held in various centers, eliciting participant feedback on an empirical model of therapeutic effectiveness based on the qualitative analysis of focus group data.RESULTS:Three primary, interrelated therapeutic domains emerged from the data, forming a model of optimal therapeutic effectiveness: 1) personal growth and self‐care (domain A), 2) therapeutic approaches (domain B), and 3) creation of a safe space (domain C). Areas of domain overlap were identified and labeled accordingly: domain AB, therapeutic humility; domain BC, therapeutic pacing; and domain AC, therapeutic presence.CONCLUSIONS:This empirical model provides detailed insights regarding the elements and pedagogy of effective communication and psychosocial care for patients who are experiencing cancer‐related distress. [See editorial on pages 000–000, this issue.] Cancer 2013. © 2013 American Cancer Society.
Anion‐Conductive Membranes with Ultralow Vanadium Permeability and Excellent Performance in Vanadium Flow Batteries
Authors: Mai Zhensheng , Zhang Huamin , Zhang Hongzhang , Xu Wanxing , Wei Wenping , Na Hui , Li Xianfeng 
Published: January 2013

AbstractAnion exchange membranes prepared from quaternized poly(tetramethyl diphenyl ether sulfone) (QAPES) were first investigated in the context of vanadium flow battery (VFB) applications. The membranes showed an impressive suppression effect on vanadium ions. The recorded vanadium permeability was 0.02×10−7–0.09×10−7 cm2 min−1, which was two orders of magnitude lower than that of Nafion 115. The self‐discharge duration of a VFB single cell with a QAPES membrane is four times longer than that of Nafion 115. The morphological difference in hydrophilic domains between QAPES and Nafion was confirmed by TEM. After soaking the membranes in VO2+ solution, adsorbed vanadium ions can barely be found in QAPES, whereas the hydrophilic domains of Nafion were stained. In the ex situ chemical stability test, QAPES showed a high tolerance to VO2+ and remained intact after immersion in VO2+ solution for over 250 h. The performance of a VFB single cell assembled with QAPES membranes is equal to or even better than that of Nafion 115 and remains stable in a long‐term cycle test. These results indicate that QAPES membranes can be an ideal option in the fabrication of high‐performance VFBs with low electric capacity loss.
Identifying leukocyte populations in fresh and cryopreserved sputum using flow cytometry
Authors: Brooks Collin R. , van Dalen Christine J. , Hermans Ian F. , Douwes Jeroen 
Published: January 2013

AbstractBackground:Airway inflammation is commonly assessed by sputum induction followed by a differential cell count (DCC) using light microscopy. This method is prone to intercounter variability and poor reproducibility. We aimed to develop a more objective method using flow cytometry (FCM).Methods:Fifty‐six sputum inductions were conducted in 41 adults (23 asthmatics). Sputum was processed, a cytospin prepared for DCC, and the remainder immunolabeled for FCM using CD45, CD14, and CD16‐specific antibodies to distinguish major leukocyte populations. Aliquots of 15 samples were frozen at −80°C to assess the effects of cryostorage. DCC and FCM were compared, and viability of individual cell populations was determined by FCM.Results:FCM and DCC, and fresh and frozen samples, were significantly correlated, R = 0.54–0.87; all P < 0.0001, and R = 0.57 to 1; P < 0.005, respectively. There was a significant neutrophil loss after cryostorage (from median 30.5–17.4% of total leukocytes; P < 0.0001). Cell viability was higher for lymphocytes compared to granulocytes or macrophages (P < 0.001). With the exception of the expected higher levels of eosinophils (P < 0.005), no significant difference in cell differentials or viability was observed between asthmatics and nonasthmatics using either DCC or FCM.Conclusions:FCM is a suitable means of assessing leukocyte populations in induced sputum. Sample storage at −80°C prior to FCM is feasible, but may be detrimental to neutrophils, although good correlations were still observed between fresh and frozen samples. Large differences in viability were found between individual cell populations suggesting that viability dye use may be necessary. © 2013 International Clinical Cytometry Society
Flow cytometry is of limited utility in the early identification of “Double‐hit” B‐cell lymphomas
Authors: Platt Mia Y. , DeLelys Michelle E. , Preffer Frederic I. , Sohani Aliyah R. 
Published: January 2013

AbstractBackground:B‐cell lymphomas with concurrent translocations of MYC and BCL2 or BCL6, also known as “double‐hit” lymphomas (DHL), are rare malignancies characterized by aggressive clinical behavior and poor prognosis. Previous reports suggest that decreased CD20 and/or CD19 expression by flow cytometry is relatively common in DHL and may help to identify cases requiring additional cytogenetic analysis.Methods:We conducted a retrospective analysis of 26 cases of DHL, and compared their flow cytometric characteristics to cases of Burkitt lymphoma (BL) and diffuse large B‐cell lymphoma (DLBCL). Cases were analyzed by four‐color flow cytometry, and bivariate dot‐plots were reviewed for light scatter characteristics, CD19, CD20, CD45, and surface light chain.Results:Relatively few DHL cases showed dim expression of CD19 or CD20, and statistically significant differences were found only in the frequency of dim CD19 expression between DHL and BL or DLBCL. Although concomitant dim CD19 and CD20 expression was exclusive to DHL, it was present in only a minority of cases.Conclusions:We conclude that although a subset of DHL expresses aberrant levels of CD19 and/or CD20 by flow cytometry, these findings are of limited utility in identifying cases requiring cytogenetic analysis due to their low frequency. Until more sensitive pathologic parameters can be identified and validated, the decision to perform cytogenetic analysis should rest on a combination of clinical, morphologic, and immunophenotypic features suggestive of high‐grade, aggressive disease. © 2013 International Clinical Cytometry Society
A VHF interferometry system for detecting anomalous propagation of FM radio broadcasting waves related to earthquakes and some preliminary results
Authors: Ohno Nozomi , Tone Yuka , Hattori Katsumi , Yamamoto Isao , Shimakura Shin , Takano Toshiaki 
Published: January 2013

AbstractEarthquake‐related anomalous electromagnetic phenomena have been reported in various frequency ranges over the past few decades. Investigation of the anomalous propagation of VHF transmitter waves is a promising approach to short‐term prediction and crustal activity monitoring. Anomalous propagation is believed to be generated by disturbances of the atmosphere above the epicenter or along the propagation path prior to large earthquakes. Consequently, over‐the‐horizon propagation has been received. A recent study shows that the appearance of anomalies was signiﬁcantly enhanced within 5 days of earthquakes with M ≥4.8. However, there is no information on the scattering location, that is, on the direction of wave arrival. Therefore, a simple interferometer system for VHF radio waves to identify the space‐time position of earthquake‐related atmospheric disturbances has been developed and installed at Chiba University. This paper describes the newly developed interferometer system and presents the results of fundamental tests to evaluate the performance of the new interferometer at Chiba. Data on over‐the‐horizon propagation of VHF radio waves obtained from 1‐year continuous measurement at Chiba are described. These are possible radio duct propagations and possible earthquake‐related anomalous propagations. © 2013 Wiley Periodicals, Inc. Electr Eng Jpn, 183(1): 16–24, 2013; Published online in Wiley Online Library (wileyonlinelibrary.com). DOI 10.1002/eej.22303
Study of molecular behavior in oxidation of insulating oil using terahertz spectroscopy
Authors: Nishimura Nobuaki , Ogura Ryuichi , Matsumoto Satoshi , Mizuno Maya , Fukunaga Kaori 
Published: January 2013

AbstractThe stock of aged power equipment is increasing and it is important to clarify the characteristics of deteriorated insulating oil. This paper describes a basic study of molecular behavior in the oxidation of insulating oil by terahertz spectroscopy. The oxidation of insulating oil was modeled by using various compositions of dodecane and 2‐octanol. The terahertz measurements indicated that signiﬁcant absorption related to hydroxyl groups (‐OH) occurred between 6 and 7 THz. The absorption band was also observed in accelerated aging alkylbenzene, which is used in power equipment as insulating oil and is sensitive to hydrogen bonds. © 2013 Wiley Periodicals, Inc. Electr Eng Jpn, 183(1): 9–15, 2013; Published online in Wiley Online Library (wileyonlinelibrary.com). DOI 10.1002/eej.22335