bluuebunny/crossref_metadata_2025_split huggingface dataset:
Experimentelle Validierung von robuster Prozessplanung und -regelung mit Gauß'schen Mischdichten
Authors: Rossner Niko , King Rudibert 
Published: January 2014

Zusammenfassung
Anhand einer exothermen chemischen Reaktion wird experimentell untersucht, welche Auswirkung der Detailgrad der
Unsicherheitsbeschreibung in der Prozessplanung und -regelung auf das reale Produktionsergebnis hat. Dazu werden zunächst zwei robuste
Steuerfolgen gegenübergestellt, welche die Prozessschwankungen mit Gauß'schen Mischdichten (GMD) bestehend aus einer bzw. 32
multivariaten Normalverteilung beschreiben. Darüber hinaus werden die Prozessverläufe zweier robuster Prozessregelungen verglichen.
Eine genauere Unsicherheitsbeschreibung führt in beiden Fällen auf einen höheren Prozessumsatz.
Effect of Work–Life Balance Practices on Firm Productivity: Evidence from Japanese Firm-Level Panel Data
Authors: Yamamoto Isamu , Matsuura Toshiyuki 
Published: January 2014

Abstract
This article examines how firm practices that could contribute to worker attainment of work–life balance (WLB) affect the total factor productivity (TFP) of a firm, by using panel data of Japanese firms from the 1990s. We observed a positive correlation between the WLB practices and TFP among sampled firms. However that correlation vanished when we controlled for the unobserved firm heterogeneity, and we found no general causal relationship in which WLB practices increase firm TFP in the medium or long run. For firms with the following characteristics, however, we found positive and sizable effects: large firms, manufacturing firms, and firms that have exhibited labor hoarding during recessions. Since these firms are likely to incur large fixed employment costs, we infer that firms investing in firm-specific human skills or having large hiring/firing costs can benefit from WLB practices through a decrease in turnover or increase in recruiting effectiveness.
Non-integrability by discrete quadratures
Authors: Casale Guy , Roques Julien 
Published: January 2014

Abstract.

We give a necessary condition for integrability by discrete quadratures of systems of difference equations: the discrete variational equations along algebraic solutions must have virtually solvable Galois groups. This necessary condition à la Morales and Ramis is used in order to prove that q-analogues of Painlevé I and Painlevé III equations are not integrable by discrete quadratures.
Homogeneous number of free generators
Authors: Aka Menny , Gelander Tsachik , Soĭfer Gregory A. 
Published: January 2014

Abstract.
We address two questions of Simon Thomas. First, we show that for
any n ≥ 3 one can find a four-generated free subgroup of SL
n
(ℤ)
which is profinitely dense. More generally, we show that an arithmetic
group Γ that admits the congruence subgroup property has
a profinitely-dense free subgroup with an explicit bound on its rank.
Next, we show that the set of profinitely-dense, locally-free subgroups
of such an arithmetic group Γ is uncountable.
Sailing Video-Imagery: Impacts on Imagery Ability
Authors: Gapin Jennifer , Herzog Tim 
Published: January 2014

Abstract
The purpose of this study was to investigate the impact of a standardized mental practice tool incorporating principles of video, modeling, and traditional-imagery,on the imagery ability of competitive college sailors. A quasi-experimental method using a quantitative pre-test/post-test design was administered with a convenience sample of collegiate sailors recruited via the Internet. An integrated video-imagery intervention was compared with a traditional verbal intervention to measure each intervention’s impact on imagery ability. The Vividness of Movement Imagery Questionnaire-2 (VMIQ-2) was used to assess external visual imagery, internal visual imagery, and kinesthetic imagery. Exposure to video-imagery resulted in significant improvement of external visual, internal visual, and kinesthetic imagery abilities. There was no significant difference between improvements from video-imagery versus traditional-imagery. Future studies should explore best combinations of imagery and observation techniques, and efficacious elements of each
Are zinc transporter type 8 antibodies a marker of autoimmune thyroiditis in non-obese adults with new-onset diabetes?
Authors: Rogowicz-Frontczak Anita , Zozulińska-Ziółkiewicz Dorota , Litwinowicz Monika , Niedźwiecki Paweł , Wyka Krystyna , Wierusz-Wysocka Bogna 
Published: January 2014

ObjectiveThe diagnosis of autoimmune diabetes in non-obese adults is based on the detection of glutamic acid decarboxylase autoantibodies (GADA), islet cell antibodies (ICA) and antibodies to tyrosine phosphatase (IA-2A). Zinc transporter 8 (ZnT8) has been identified as a new autoantigen in patients with type 1 diabetes mellitus. The coincidence of autoimmune thyroiditis (AITD) with diabetes is common; therefore, screening of TSH and thyroid peroxidase antibodies (ATPO) is recommended during the diagnosis of diabetes. In this study, we determined whether the occurrence of islet autoantibodies is associated with a positive titre of ATPO in newly diagnosed adult-onset autoimmune diabetic patients.Design and methodsThe study involved 80 non-obese adults aged 44 (interquartile range (IQR): 37–51) years with a BMI of 24.0 (IQR: 22.2–26.0) kg/m2and new-onset diabetes. The markers of autoimmune diabetes (GADA, ICA, IA-2A and ZnT8A), TSH and thyroid peroxidase antibodies (ATPO) were evaluated.ResultsIn the study population, 70% (n=56) of the subjects were positive for at least one of the four assessed markers of autoimmune diabetes (83.9% GADA, 62.5% ICA, 42.8% IA-2A and 33% ZnT8A) and 37.5% of the subjects were positive for ATPO. The ZnT8A-positive subjects had higher ATPO titres than the ZnT8A-negative subjects (172.7 (IQR: 0.36–410.4) vs 92.4 (IQR: 0–23.7) IU/ml,P=0.001). Based on the assessed islet autoantibodies, the occurrence of positive ZnT8A and GADA was found to be related to a positive titre of ATPO using logistic regression (OR=5.48, 95% CI: 1.65–18.14,P=0.006 and OR=3.42, 95% CI: 1.09–10.71,P=0.03 respectively).ConclusionsIn non-obese adults with new-onset diabetes, the presence of GADA and especially ZnT8 autoantibodies increases the risk of AITD.
Metamodernism: Narratives of Continuity and Revolution
Authors: James David , Seshagiri Urmila 
Published: January 2014

The task for contemporary literature is to deal with the legacy of modernism.—Tom McCarthy (2010)A century separates us from an iconic moment of aesthetic metamorphosis: 1914 witnessed the appearance of James Joyce'sDubliners, Gertrude Stein'sTender Buttons, Mina Loy's “Parturition,” and the vorticist journalBlast.It was the year Dora Marsden and Harriet Shaw Weaver, aided by Ezra Pound, started the literary review theEgoistin London and Condé Nast and Frank Crowninshield launchedVanity Fairin New York. Arnold Schoenberg's atonal symphonic works assaulted classical sonorities; Wassily Kandinsky elevated the purity of geometric form above the functional work of visual representation. Most crucially, 1914 saw the assassination of Archduke Ferdinand in Sarajevo and the subsequent outbreak of the First World War. Cutting a bloody, four-year swath across Europe, the war took almost forty million lives and rendered all subsequent formal innovation inseparable from cultural devastation: thus the intricate, ruptured literary architectures ofThe Waste Land(1922),Ulysses(1922), andTo the Lighthouse(1927).
Enhanced Inducible Costimulator Ligand (ICOS-L) Expression on Dendritic Cells in Interleukin-10 Deficiency and Its Impact on T-Cell Subsets in Respiratory Tract Infection
Authors: Gao Xiaoling , Zhao Lei , Wang Shuhe , Yang Jie , Yang Xi 
Published: January 2014

AbstractAn association between inducible costimulator ligand (ICOS-L) expression and interleukin (IL)-10 production by dendritic cells (DCs) has been commonly found in infectious disease. DCs with higher ICOS-L expression and IL-10 production are reportedly more efficient in inducing regulatory T cells (Tregs). Here we use the Chlamydia muridarum(Cm) lung infection model in IL-10 knockout (KO) mice to test the relationship between IL-10 production and ICOS-L expression by DCs. We examined ICOS-L expression, the development of T-cell subsets, including Treg, Th17 and Th1 cell, in the background of IL-10 deficiency and its relationship with ICOS-L/ICOS signaling after infection. Surprisingly, we found that the IL-10 KO mice exhibited significantly higher ICOS-L expression by DCs. Moreover, IL-10 KO mice showed lower Tregs but higher Th17 and Th1 responses, but only the Th17 response depended on ICOS signaling. Consistently, most of the Th17 cells were ICOS+, whereas most of the Th1 cells were ICOS− in the infected mice. Furthermore, neutralization of IL-17 in IL-10 KO mice significantly exacerbated lung infection. The data suggest that ICOS-L expression on DC may be negatively regulated by IL-10 and that ICOS-L expression on DC in the presence or absence of IL-10 costimulation may promote Treg or Th17 response, without significant impact on Th1.
Emerging Role of High-Mobility Group Box 1 (HMGB1) in Liver Diseases
Authors: Chen Ruochan , Hou Wen , Zhang Qiuhong , Kang Rui , Fan Xue-Gong , Tang Daolin 
Published: January 2014

AbstractDamage-associated molecular pattern (DAMP) molecules are essential for the initiation of innate inflammatory responses to infection and injury. The prototypic DAMP molecule, high-mobility group box 1 (HMGB1), is an abundant architectural chromosomal protein that has location-specific biological functions: within the nucleus as a DNA chaperone, within the cytosol to sustain autophagy and outside the cell as a DAMP molecule. Recent research indicates that aberrant activation of HMGB1 signaling can promote the onset of inflammatory and autoimmune diseases, raising interest in the development of therapeutic strategies to control their function. The importance of HMGB1 activation in various forms of liver disease in relation to liver damage, steatosis, inflammation, fibrosis, tumorigenesis and regeneration is discussed in this review.
Cervical HPV Infection in Female Sex Workers: A Global Perspective
Authors: Soohoo Melissa , Blas Magaly , Byraiah Gita , Carcamo Cesar , Brown Brandon 
Published: January 2014

Introduction:Approximately 291 million women worldwide are HPV DNA carriers. Studies have indicated that having multiple sexual partners may lead to higher HPV transmission. Thus female sex workers (FSWs) may be at greater risk of infection compared to the general population. Herein we review publications with data on FSW cervical HPV test results. We also examine variations of HPV prevalence and risk behaviors by region. Knowledge of prevalent HPV types in FSWs may lead to improved prevention measures and assist in understanding vaccination in high-risk groups.Methods:We conducted a review of the literature by searching PUBMED using the terms “prostitution” or “female sex workers”, “human papillomavirus” or “HPV”, and “prevalence” or “PCR” to find articles. We excluded studies without HPV testing or HPV type specific results, or unconventional HPV testing.Results:A total of 35 peer-reviewed publications were included in our review. High risk HPV types 16 and 18 ranged from 1.1-38.9‰ in prevalence. In addition to high-risk HPV types, newer studies reported non-carcinogenic HPV types also of high prevalence. The most prevalent HPV types reported among FSWs included HPV 6 (11.5%), 16 (38.9%), 18 (23.1%), 31 (28.4%), 52 (32.7%), and 58 (26.0%).Conclusions:Female sex workers have an overall high prevalence of HPV infection of high-risk types as evident through various testing methods. FSWs are thought to be at increased risk of cervical cancer because of high HPV exposure. This highlights the need for HPV and cervical prevention campaigns tailored to FSWs.
New vitreous matrix for chromium waste immobilization
Authors: Lazău Ioan , Vancea Cosmin 
Published: January 2014

Abstract
Common waste glasses (window, bottle glass or tableware) with fly ash form a glass matrix for chromium waste immobilization. Soluble chromium from residual waters was adsorbed on fly ash; the resulting solid contained 23.7% Cr6+. The three glass wastes, chromium-containing fly ash, and borax were used to make glasses in weight ratios waste glass: borax: fly ash of 1: 1: 1 and 1.5: 0.5: 1. The hydrolytic stability ranged from 18.46 to 28.13 µg g−1 soluble Na2O, qualifying them in the HGB1 class. The chemical stability, characterized by the dissolution rate, was 0.011–0.077 µg cm−2 h−1, depending on the glass composition and the aggressive medium pH. The chromium leachability is influnced by the glass composition and the pH of the leaching solution, ranging between 0–0.015% of the total chromium. Chromium waste vitrification is a viabile solution with multiple economic advantages.
Depressive disorder and its mental comorbidity in patients attending psychiatry OPD at Nepalgunj Medical College, Kohalpur
Authors: Belbase M , Khan TA , Jalan RK 
Published: January 2014

Background: Depression is one of the commonest mental health problem and its association with suicide as the most common etiology makes it a ruthless killer of all the psychiatric problems we fight with. Identification and management of co-morbid condition is important from the epidemiological and management point of view. Aim of this paper is to study about depression and its psychiatric co-morbidity in the subjects visiting to psychiatric care centre of Nepalgunj medical college. Methods: This was a descriptive study done in patients attending psychiatry OPD of Nepalgunj Medical College, Kohalpur, for six months, from the month of Baisakh to Ashwin 2069. Results: Out of the total 266 subjects (n=266), the most common age group was 21-30 years 98 (36.84%), followed by 11-20 years 67 (25.19%). Female was the dominant gender in both the age groups representing 71 and 47 respectively. The most common co-morbid diagnosis in depression was dissociation 54 (44.26%) followed by headache (27.05%). Other co-morbid diagnosis were; suicidal attempt (5.74%), alcohol use (4.1%) and others (18.85%) Conclusions: Depression is a common psychiatric entity with various psychiatric co-morbidities. The most common co-morbid diagnosis was dissociation, followed by headache. DOI: http://dx.doi.org/10.3126/jpan.v2i2.9720 J Psychiatrists’ Association of Nepal Vol.2, No.2, 2013 18-21
Socio-demographic and clinical profile of patients attending a mental health camp: A study from Kanchanpur district of western Nepal
Authors: Khan TA , Belbase M 
Published: January 2014

Background: Mental health is an ignored area of general health care system despite the magnitude of problem and financial burden on families and whole country. In our country, psychiatric services are out of reach to majority of population because of inadequate mental health professionals, lack of awareness and lack of proper mental health policy. This study is conducted with the objective to know socio-demographic and diagnostic profile of patients from a mental health check up camp conducted at Belauri, Kanchanpur district from far western region of Nepal. Material and Methods: This is a descriptive study, comprised of all consecutive participants i.e. 128 patients attending Maryknoll mental health check up camp at Belauri town of Kanchanpur district, Nepal. The Study was performed in March 2013. Socio-demographic data and clinical diagnosis based on International Classification of Disease- 10 diagnostic research criteria were collected and analyzed. Results: Out of 128 subjects studied, highest number of participants (35.94%) belonged to age group 21- 30 yrs followed by age group 11-20 yrs (18.75%) and age group 31-40 yrs (16.40%). The most common psychiatric morbidity was found to be Neurotic, stress related & somatoform disorders (23.45%) followed by mood disorder in 24 (18.75%) patients and Headache (Migraine & Tension type) in 18 (14.07%) patients. Conclusion: The commonest age group affected with mental illness is younger age groups and Neurotic, stress related & somatoform disorders are the most common psychiatric morbidity followed by mood disorders. DOI: http://dx.doi.org/10.3126/jpan.v2i2.9724 J Psychiatrists’ Association of Nepal Vol.2, No.2, 2013 35-38
Efficacy of local polymer-based and systemic delivery of the anti-glutamatergic agents riluzole and memantine in rat glioma models
Authors: Yohay Kaleb , Tyler Betty , Weaver Kyle D. , Pardo Andrea C. , Gincel Dan , Blakeley Jaishri , Brem Henry , Rothstein Jeffrey D. 
Published: January 2014

Object
The poor outcome of malignant gliomas is largely due to local invasiveness. Previous studies suggest that gliomas secrete excess glutamate and destroy surrounding normal peritumoral brain by means of excitotoxic mechanisms. In this study the authors assessed the effect on survival of 2 glutamate modulators (riluzole and memantine) in rodent glioma models.

Methods
In an in vitro growth inhibition assay, F98 and 9L cells were exposed to riluzole and memantine. Mouse cerebellar organotypic cultures were implanted with F98 glioma cells and treated with radiation, radiation + riluzole, or vehicle and assessed for tumor growth. Safety and tolerability of intracranially implanted riluzole and memantine CPP:SA polymers were tested in F344 rats. The efficacy of these drugs was tested against the 9L model and riluzole was further tested with and without radiation therapy (RT).

Results
In vitro assays showed effective growth inhibition of both drugs on F98 and 9L cell lines. F98 organotypic cultures showed reduced growth of tumors treated with radiation and riluzole in comparison with untreated cultures or cultures treated with radiation or riluzole alone. Three separate efficacy experiments all showed that localized delivery of riluzole or memantine is efficacious against the 9L gliosarcoma tumor in vivo. Systemic riluzole monotherapy was ineffective; however, riluzole given with RT resulted in improved survival.

Conclusions
Riluzole and memantine can be safely and effectively delivered intracranially via polymer in rat glioma models. Both drugs demonstrate efficacy against the 9L gliosarcoma and F98 glioma in vitro and in vivo. Although systemic riluzole proved ineffective in increasing survival, riluzole acted synergistically with radiation and increased survival compared with RT or riluzole alone.
Increased risk of acute kidney injury associated with higher infusion rate of mannitol in patients with intracranial hemorrhage
Authors: Kim Min Young , Park Ji Hyeon , Kang Na Ree , Jang Hye Ryoun , Lee Jung Eun , Huh Wooseong , Kim Yoon-Goo , Kim Dae Joong , Hong Seung-Chyul , Kim Jong-Soo , Oh Ha Young 
Published: January 2014

Object
Mannitol, an osmotic agent used to decrease intracranial pressure, can cause acute kidney injury (AKI). The objectives of this study were to assess the impact of mannitol on the incidence and severity of AKI and to identify risk factors and outcome for AKI in patients with intracranial hemorrhage (ICH).

Methods
The authors retrospectively evaluated 153 adult patients who received mannitol infusion after ICH between January 2005 and December 2009 in the neurosurgical intensive care unit. Multivariate analysis was used to evaluate the risk factors for AKI after ICH. Based on the odds ratio, weighted scores were assigned to predictors of AKI.

Results
The overall incidence of AKI among study participants was 10.5% (n = 16). Acute kidney injury occurred more frequently in patients who received mannitol infusion at a rate ≥ 1.34 g/kg/day than it did in patients who received mannitol infusion at a rate < 1.34 g/kg/day. A higher mannitol infusion rate was associated with more severe AKI. Independent risk factors for AKI were mannitol infusion rate ≥ 1.34 g/kg/day, age ≥ 70 years, diastolic blood pressure (DBP) ≥ 110 mm Hg, and glomerular filtration rate < 60 ml/min/1.73 m2. The authors developed a risk model for AKI, wherein patients with a higher risk score showed a graded association with a higher incidence of AKI.

Conclusions
The incidence of AKI following mannitol infusion in patients with ICH was 10.5%. A higher mannitol infusion rate was associated with more frequent and more severe AKI. Additionally, age ≥ 70 years, DBP ≥ 110 mm Hg, and established renal dysfunction before starting mannitol therapy were associated with development of AKI.
La parité dans l'entreprise, un enjeu économique et non un phénomène sociétal
Authors: Monsellato Gianmarco 
Published: January 2014

Si les femmes représentent 52 % de la population française, et 51,9 % de la population active, elles restent marginales dans les hautes fonctions de l’entreprise, en France comme dans de nombreux pays étrangers. Ayant constaté que dans le secteur juridique, plus de la moitié des jeunes diplômés sortant des facultés de droit sont des femmes, il nous était impossible chez Taj de nous priver de ce vivier de compétences. À ce titre, nous considérons que la parité n’est pas un objectif utopique mais une urgence économique. Le plafond de verre, premier frein à la parité dans l’entreprise, ne peut être traité par les femmes exclusivement mais doit être porté par les décideurs au rang des priorités stratégiques de l’entreprise.
Insights into functional tea infused-chitosan hydrogels as potential bio-active restorative materials
Authors: Perchyonok Tamara V. , Zhang Shengmiao , Grobler Sias , Oberholzer Theunis , Massey Ward 
Published: January 2014

Abstract
Introduction: We described novel chitosan hydrogels (chitosan-H) containing tea infusions (green, red and black) as functional additive prototypes with special focus on the design and functionality of dual action composite restorative materials. Their intended uses include remineralizing bases/liners, therapeutically active restorative materials and/or functional additives as well as functional prototype of the drug delivery system. Materials and Methods: The above mentioned hydrogels were prepared by dispersion of the corresponding component in glycerol and acetic acid with the addition of chitosan gelling agent. The surface morphology scanning electron microscope (SEM), release behavior (physiological pH as well as acidic conditions), stability of the hydrogels as well as antioxidant capacity of the tea infused hydrogels was evaluated. Results: It was found that all the anti-oxidant chitosan-H hydrogels treated dentine gave significantly (P < 0.05; Non-parametric ANOVA test) higher shear bond strength values than dentine treated or not treated with phosphoric acid. Overall, there was a small relapse in the shear bond strength after 6 months. The SEM is employed to observe the surface of the newly made functional restorative materials. The anti-oxidant capacity of various black, red and green tea infusions was investigated and demonstrated increased antioxidant stability of the newly prepared material stability. Conclusion: We have developed and evaluated several functional chitosan hydrogels with several targets as therapeutic restorative materials, the added benefits of their unique functionality involve increased dentin adhesive bond strengths (after 24 h and after 6 month), concept of using functional materials as carriers for pro-drugs as well as display certain degree of defense mechanism for a free radical damage.