bluuebunny/crossref_metadata_2025_split huggingface dataset:
POLÍTICAS PÚBLICAS E A PERCEPÇÃO DE ESTIGMA DO TRANSTORNO MENTAL NO INTERIOR DO RIO GRANDE DO NORTE
Authors: Peixoto Maria Tatiana , Da Silva Chaves Francisco Gilmar , De Souza Bertulino José , Figueiredo Fábio Fonseca 
Published: July 2024

Teve-se como objetivo neste recorte, apresentar e discutir o cenário das Políticas Públicas no Brasil e cotizá-lo com a percepção sobre estigmas do transtorno mental da comunidade universitária no Alto Oeste Potiguar. Neste sentido, tem-se alguns aspectos importantes no debate das Políticas Públicas com viés na saúde e sua inadequação à realidade da população, considerando a abrangência e profundidade das questões relacionadas ao sofrimento psíquico e saúde mental e como os sujeitos da pesquisa a incorporam. Foram analisados 96 sujeitos dos estados da Paraíba, Ceará e Rio Grande do Norte através de questionário aplicado via google forms, divulgado e implementado em conta do Instagram, criada para este fim, com questões relacionadas ao aspecto social, econômico e cultural, e de abordagens específicas da relação estigma do transtorno mental. Os resultados apontaram que os investigados são predominantemente do sexo feminino, com idade igual ou superior a 25 anos e com pouco conhecimento da abrangência e performance de uma Política Pública, sobretudo na saúde.
Rasch modeling approach to measure the quality of algebraic thinking questions for junior high school students
Authors: Rusyid Husnul Khatimah , Suryadi Didi , Herman Tatang , Adnan Mazlini , Lutfi Ahmad , Mukhibin Ahmad 
Published: July 2024

[Abstract]: Algebraic thinking skills include the ability to generalize based on ideas involving symbols, as well as the ability to represent and solve algebraic problems. This study aims to describe the quality of algebraic thinking questions on linear equation material using the Rasch model approach. Data were collected through six essay questions, where each question represents an indicator of students' algebraic thinking. The research subjects consisted of 37 8th grade students selected using the purposive sampling technique. The results of item analysis show that all questions fall into the valid category. Furthermore, the instrument demonstrates overall reliability with a score index of 0.81, placing it in the good category. Analysis of the difficulty level of the questions revealed that 2 items fell into the very difficult category, 1 item was difficult, 1 item was moderate, 1 item was easy, and 1 item was very easy. Overall, the developed algebraic thinking ability instrument meets Rasch modeling criteria and can effectively measure students' algebraic thinking ability. Teachers can utilize this instrument as an assessment tool to evaluate students' algebraic thinking skills in mathematics learning, particularly in linear equation material.
[Abstrak]: Kemampuan berpikir aljabar mencakup kemampuan dalam melakukan generalisasi berdasarkan ide-ide yang melibatkan simbol-simbol serta kemampuan dalam merepresentasikan dan menyelesaikan masalah aljabar. Penelitian ini bertujuan untuk menggambarkan kualitas soal berpikir aljabar pada materi persamaan linear menggunakan pendekatan model Rasch. Data dikumpulkan melalui 6 soal esai, di mana masing-masing soal mewakili indikator berpikir aljabar siswa. Subjek penelitian terdiri dari 37 siswa kelas VIII yang dipilih menggunakan teknik purposive sampling. Hasil analisis item menunjukkan bahwa semua soal termasuk dalam kategori valid. Selain itu, instrumen secara keseluruhan menunjukkan reliabilitas dengan indeks skor sebesar 0,81 yang termasuk dalam kategori baik. Analisis tingkat kesulitan soal mengungkapkan bahwa 2 item masuk dalam kategori sangat sulit, 1 item sulit, 1 item sedang, 1 item mudah, dan 1 item sangat mudah. Secara keseluruhan, instrumen kemampuan berpikir aljabar yang dikembangkan memenuhi kriteria pemodelan Rasch dan dapat digunakan untuk mengukur kemampuan berpikir aljabar siswa. Instrumen ini dapat dimanfaatkan oleh guru sebagai alat penilaian untuk mengevaluasi kemampuan berpikir aljabar siswa pada pembelajaran matematika, khususnya materi persamaan linear.
EFFECT OF DIFFERENCES BROMELAIN ENZYME CONSENTRATION ON PROTEIN HYDROLYSATE FROM WASTE OF TILAPIA VISCERA (Oreochromis sp.) ON ANTIOXIDANT ACTIVITY
Authors: Muhammad Athoillah Sholahuddin  , Lastuti Nunuk Dyah Retno , Amin Muhamad 
Published: July 2024

Tilapia is a commodity that is widely consumed by the public, especially in Indonesia. Fresh tilapia offal has a protein content composition of 55.55%, so to increase its selling value it is often made into protein hydrolysate. Protein hydrolysis using enzymes is an effective way, because it can make protein hydrolysates avoid damage to certain amino acids. Proteolytic enzymes have many types and one that can be used as a hydrolyzer, in producing protein hydrolysates is bromelain enzyme. The purpose of this study was to determine the effect of proteolytic enzyme type and hydrolysis time on antioxidant activity of protein hydrolysate from Oreochromis sp. offal waste. This study used RAL 2 factors and each was repeated 3 times. The first factor was the concentration of bromelain enzyme used, namely control concentration, 1%, 2% and 3%. The second factor was the hydrolysis time, which was 4 hours, 6 hours and 8 hours. The data obtained were analyzed and continued with antioxidant activity test, hydrolysis degree test and protein content test. The best concentration of bromelain enzyme as antioxidant was 3% concentration for 6 hours hydrolysis with IC50 value of 82.53µg/mL, the best DH of 82.25%±4.03 and the highest protein content of 54.55%.

Keywords: Antioxidant, bromelain enzyme, tilapia offal, protein hydrolysate
THE EFFECT OF LASER-ASSISTED HATCHING ON PREGNANCY OUTCOMES OF VITRIFICATION FROZEN EMBRYO TRANSFER
Authors: Vellyana Lie  , Andri Rezano  , Tono Djuwantono  , Maitra Djiang Wen  
Published: July 2024

Highlights

LAH might effectively increase pregnancy outcomes for frozen-thawed embryo transfer.
Zona pellucida drilling might help increase pregnancy outcomes in FET.

Abstract
Background: Zona Pellucida (ZP) thickness of less than 16 mm is better for embryo implantation inside the endometrium. Laser Assisted Hatching (LAH) is commonly used, especially in non-contact mode, using a 1.48-um infrared diode laser beam because of its short exposure time, accurate positioning, simple operation, indirect contact, safety, and effectiveness. Objective: This paper describes the potential of laser-assisted hatching in biochemical pregnancy outcomes in Frozen Embryo Thawed transfers. Material and Method: The total number of patients enrolled in this study was 141. Patients were prospectively treated during embryo transfers at Pusat Fertilitas Bocah Indonesia, Primaya Hospital at Tangerang, Indonesia, from December 2020 until December 2021. Result: There were no significant differences between the LAH and no-LAH groups regarding average age, infertility duration, infertility type, and etiology of infertility (p>0.05). In the same line, the blastocyst (0.76 ± 0.87; 1.25 ± 1.08) compared with cleavage (0.72 ± 0.84; 0.67 ± 0.98) (p<0.534 and p< .032). There was no significant difference, even though clinically, the proportions of live births, multiple pregnancies, biochemical pregnancies, and ongoing pregnancies in the LAH group were not exceptions to the outcomes of failures and miscarriages. Conclusion: LAH did not appear to increase the pregnancy rate in this study. However, the methodology seems to reduce bias in this study by considering methodology for selecting FET embryos based on the cryopreserved condition, embryo quality, and precise LAH.
AGE, SEX, AND TYPES OF OCCUPATION WITH HISTOPATHOLOGICAL TYPES IN PATIENTS WITH OCULAR SURFACE SQUAMOUS NEOPLASIA (OSSN) IN A TERTIARY HOSPITAL IN SURABAYA, INDONESIA
Authors: Stella Agatha Widjaja  , Delfitri Lutfi  , Linda Dewanti  , Alphania Rahniayu  , Fitria Kusumastuti  
Published: July 2024

Highlights

The histopathological types of OSSN were significantly associated with age and occupation.
The study's findings enhance the understanding of OSSN in Indonesia and emphasize the importance of UV exposure, occupation, and age in its development.

Abstract
Background: Ocular Surface Squamous Neoplasia (OSSN) is a spectrum of tumors affecting the conjunctiva and cornea, in which a more invasive type of OSSN has a higher recurrence rate. As a tropical country, Indonesia is constantly exposed to intense ultraviolet (UV) radiation, the main risk factor for OSSN. Despite this, there are very few studies regarding OSSN in Indonesia. Objective: This study aimed to analyze the association between sociodemographic characteristics such as age, sex, and types of occupation (outdoor and indoor) and histopathological types of OSSN to fill the gap in research and contribute to early diagnostic strategies. Material and Method: Sociodemographic and histopathological data were extracted from the medical records of patients who were histopathologically diagnosed with OSSN at Dr. Soetomo General Hospital from 2017 to 2021. Data from 88 samples that met the inclusion and exclusion criteria were classified and analyzed with descriptive statistics and a two-sided Fisher's exact test using SPSS version 27.0 (IBM Corp., Armonk, N.Y., USA). Result: The exact test results of the two-sided fisher revealed a statistically significant relationship between age (p = 0.0004) and occupation type (p = 0.049) with histopathological types of OSSN. However, no significant association was found between sex and histopathological types of OSSN (p = 0.130). Conclusion: Age and occupation were found to have a significant association with the histopathological types of OSSN, reinforcing the need for further exploration of its strength and nature to be considered by future researchers.
Joint inversion of ambient noise surface wave and gravity data with variation of information coupling
Authors: Shi Zhanjie , Wang Chao , He Xinxin , Du Tengjiao 
Published: July 2024

Abstract

Joint inversion of surface wave and gravity data can reduce non-uniqueness of individual inversion and has been applied in the research of the crust and lithospheric mantle. Direct parameter coupling is mainly used for jointly inverting the both dataset in the current research, which need specifying a function relationship between shear wave (S-wave) velocity and density. It can result in spurious features when the models violate the parameter relationship. Moreover, deriving an appropriate velocity-density function is difficult and a single physical property relationship may not always be suitable for all regions. In this study, we present a new joint inversion algorithm for ambient noise surface wave and gravity data with variation of information (VI) coupling. The correlation between S-wave velocity and density models is constructed by a one-to-one relationship with VI. The effectiveness of the algorithm is verified using the synthetic and field data. The results of synthetic examples indicate that density anomalies have been recovered accurately by the joint inversion, but they are almost not imaged by the individual inversion. S-wave velocity models recovered by the joint inversion are more accurate than that from the individual inversion. And the fitting parameter relationship of the joint inversion models is closer to the true model than individual inversion. In the field case from the southeast of Tibetan Plateau, the S-wave velocity model of joint inversion has a higher resolution than separate inversion. Density model recovered by the joint inversion clearly displays crustal structures, which have been severely distorted in the individual inversion model. Joint inversion with VI coupling is an effective and valuable approach for inverting surface wave and gravity data.
Assessing the Performance of the Block Maxima Method in Estimating Market Risk
Authors: Cervantes Mª Ángeles Navarro , Benito Sonia , López-Martín Carmen 
Published: July 2024

Abstract

Extreme value theory (EVT) has emerged as one of the most important statistical disciplines for predicting the probability of unusual events from observed outliers. In the context of this theory, two approaches have been developed for selecting the extreme values of a sample and for modeling them: the block maxima method (BMM) and the peak over threshold approach (POT). This paper focuses on the block maxima method (BMM) and its ability to measure market risk. The study is conducted for a set of 15 portfolio assets that are very well diversified. To analyze the robustness of the results, we consider different block sizes. The results obtained are very conclusive. Unlike the POT method, which has been proven to be very successful in measuring market risk, the maximum block method yields very poor results. Furthermore, these results are clearly sensitive to the selected block size. The superiority of the POT method is evident.
JEL classification: G17; G31
Estimating Consumption-based Ecological Footprint for Sustainability Assessment in the Indian States: Application of Environmentally Extended Multi-Regional I-O Model
Authors: Kumar Shailesh , Nayak Diptimayee 
Published: July 2024

Abstract

India is the most populous country in the world which shares eighteen percent of the total population. Consequently, its states and union territories are in ecological overshoot, depleting and polluting the biophysical basis of its own existence. In this context, understanding ecological footprint which is a land-based composite indicator for assessing the environmental impact of human activities at sub-national level and assessing the sustainability has become crucial. By employing environmentally extended Multi-Regional Input Output (MRIO) model, this study estimates consumption-based ecological footprint and bio capacity of 28 states and 4 union territories (UTs) in the country for the year 2015, and analyse the estimated Ecological Footprint and Bio Capacity across the states in India through sustainability quadrants. The study finds that most Indian states and union territories had a negative ecological balance and was completely unsustainable in the year 2015, which means that states’ Ecological Footprint (EF) exceeded their Bio Capacity (BC). In other words, most Indian states were depleting their natural resources faster than their regeneration or import from elsewhere. The present study confirms that the most efficient way of improving ecological balance and making states ecologically sustainable can be achieved by reducing carbon footprint through dynamic and rational change in consumption behaviour.
SREBF1 is a Potential Prognostic and Immunological Biomarker in Pan-Cancer
Authors: Zhang Xiaoyan , Pu Lei , Pu Cheng , Li Yuqiang 
Published: July 2024

Abstract

Reprogramming of lipid metabolism is a new mark of malignancy. Sterol Regulatory Element-Binding Transcription Factor 1 (SREBF1) plays a central role in lipid metabolism, but has rarely been reported. This study aimed to analyze the expression, prognosis and immunological significance of SREBF1 in pan-cancer. SREBF1 expression profiles were obtained from The Cancer Genome Atlas (TCGA), Genotype-Tissue Expression (GTEx) and Cancer Cell Line Encyclopedia (CCLE) databases. Area under the ROC curve, Cox regression and Kaplan-Meier analysis were performed to assess the clinical diagnostic and prognostic value of SREBF1. Subsequently, its biological functions and its correlations with tumor microenvironment (TME), chemokines, immune checkpoints, immune cell infiltration, immune stimulator, immune inhibitors, mismatch repair (MMR), tumor mutational burden (TMB) and microsatellite instability (MSI) were assessed, and mRNA-miRNA-lncRNA network was constructed. SREBF1 was found to be highly expressed in 15 cancers, had diagnostic value in 24 cancers, and was an independent key factor in the prognosis of multiple cancers. Moreover, SREBF1 significantly correlated with TME and immune-related functions in multiple cancers, and was mainly involved in metabolism- and immune-related functions. Finally, we provided many lncRNA and miRNA targets regulating SREBF1. Taken above, our study highlights SREBF1 as a promising prognostic and immunological biomarker in pan-cancer.
Shrinkage Behaviour of Self-Compacting Concrete with Higher Binder Content: Experimental Results and Predictive Equation
Authors: Bhirud Yuvaraj , Vaidya Om , More Satish , Shaikh Ayub , Pawar Amol , Pawar Lalit , Yeole Pradeep 
Published: July 2024

Abstract

This research breaks new ground in self-compacting concrete (SCC) by exploring the benefits of incorporating more binder. We investigate three concrete mixtures with varying binder content (550, 600, and 650 kg/m 3) to assess their workability, compressive strength, and shrinkage. Our findings reveal a significant increase in strength throughout the concrete's lifespan with higher binder content. Additionally, the mix exhibits enhanced stability and cohesion. The research also explores the cost-effective use of fly ash as a partial binder replacement, reducing the reliance on expensive superplasticizers. However, existing prediction models (IS 1343-2012, BS EN 1992-1-1-2004, and ACI 209 R-92) were found inaccurate for high-binder SCC shrinkage. To address this gap, we propose a novel equation for predicting shrinkage in SCC with increased binder content, based on our experimental data. This innovative approach paves the way for the optimized design and cost-effective use of high-strength SCC in construction projects.
The effect of escape rooms on teamwork attitudes and intensive care knowledge among new nurses in the ICU
Authors: HU Qiulan , BAI Yangjuan , MO Yuanxiang , MA Rui , DING Lan , ZHOU Ming , ZHANG Yimei , MA Fang 
Published: July 2024

Abstract

Background Despite nurses needing a very long time to accumulate intensive care knowledge and skills, there is a severe shortage of intensive care nurses worldwide. This study aimed to examine the effect of an escape room teaching strategy on knowledge of managing intensive patients, teamwork attitudes, satisfaction, and willingness to participate in the program among new nurses.
Methods A convenience sampling approach was utilised to enlist 84 new nurses from the First Affiliated Hospital of Kunming Medical University in this quasi-experimental one-group pretest-posttest study. An online examination and questionnaire were used to assess new nurses' knowledge of intensive care and teamwork attitudes before and after the escape room training game, as well as to measure satisfaction and willingness to implement this training.
Results Fifteen groups of new nurses participated in the escape room training program. The mean knowledge score after the intervention significantly varied from that before the intervention (p = 0.000), and there were significant differences in the mean T-TAQ total score (p = 0.000) and in the dimensions of teamwork (p = 0.000), leadership (p = 0.000), situation monitoring (p = 0.019), mutual support (p = 0.000), and communication (p = 0.000) before and after the intervention. The new nurses were highly satisfied with the escape room training program (9.23 ± 0.869), and the majority of them (95.24%) wanted to participate in similar training.
Conclusion The implementation of the escape room has a positive impact on the promotion of acknowledged knowledge of intensive care, together with increasing teamwork attitudes, satisfaction and willingness among new nurses. Escape room training is suggested as a popular training game that can be used to attract new nurses to gain difficult knowledge of intensive care and enhance the teamwork attitude of players.
Birth weight impacts physical and motor performance of school-aged children in Matola, Mozambique.
Authors: Guiliche Euclides da Conceição , Campos Jéssica de Oliveira , Pereira Jéssica Gonzaga , Tchamo Mario Eugênio , Leandro Carol Gois , Saranga Silvio Pedro José , Costa-Silva João Henrique 
Published: July 2024

Abstract

Low birth weight (LBW) affects, specially, low-and middle-income countries and is associated with impairments in growth and the development of neuromotor skills. This study evaluated the influence of birth weight on body composition, cardiometabolic and physical fitness and motor coordination in school-age children in Matola, province of Maputo – Mozambique. Quantitative cross-sectional study carried out with school-age children of both genders. Children were divided into three groups: low birth weight (LBW: n=15); insufficient birth weight (IBW: n=43) and normal birth weight (NBW: n=87). Anthropometric parameters, physical fitness and neuromotor performance were evaluated. The groups were compared by one-way Anova or Kruskal-Wallis test and correlations between the studied variables were investigated using Spearman's test and partial correlation. LBW does not seem to affect anthropometric parameters in this age group. On the other hand, it seems to compromise performance during sprint running and VO2 maximum. Furthermore, a negative correlation was found between birth weight and body fat, sprint running and monopedal jumping. Birth weight also showed a positive correlation with VO2 maximum. Thus, our data suggest that LBW is related to lower performance in the speed and VO2 maximum tests, even after adjustments for age, gender and actual BMI.
The Effectiveness of Augmented Reality/Mixed Reality in Medical Education: A Meta- Analysis
Authors: Zhang Ruoxuan , Jin Xiaoyan , Liu Ming , Tong Hoi Yee 
Published: July 2024

Abstract

Background
Augmented reality (AR) and mixed reality (MR) are increasingly being applied in the field of medical education. However, the effectiveness and acceptance of AR/MR in different teaching scenarios remain unclear. This meta-analysis aimed to examine the effectiveness of AR/MR in improving medical students' knowledge and skills training.
Methods
PubMed, Embase, Cochrane Library, PsycINFO, Education Source, Education Resources Information Center, CINAHL, Web of Science Core Collection, China National Knowledge Infrastructure, WanFang, WeiPu and Chinese BioMedical Literature databases were searched. The search encompassed literature from database establishment to December 2023. Studies examining the use of AR/MR in medical education and reporting outcomes related to knowledge learning or skill training were included. The data were analyzed using Stata version 15.1 software.
Results
29 publications were included in this meta-analysis. Compared to traditional teaching methods, AR/MR-assisted teaching showed greater effectiveness in medical skills training, as indicated by the higher skill scores (WMD = 12.31, 95% CI: 4.12 to 20.50), reduced failure rate (RD=-0.13, 95% CI: -0.19 to -0.07), and shortened performance time (SMD = -0.19, 95% CI: -0.32 to -0.06). However, AR/MR did not significantly improve knowledge acquisition (WMD = 2.78, 95% CI: -1.89 to 7.45). The questionnaire survey revealed the advantages of AR/MR in terms of perceived usefulness (PU) (WMD = 0.27, 95% CI: 0.00 to 0.53), perceived ease of use (PEOU) (WMD = 0.35, 95% CI: 0.13 to 0.57), and enjoyment (WMD = 0.67, 95% CI: 0.20 to 1.13).
Conclusion
This meta-analysis highlights the effectiveness and user acceptance of AR/MR in medical education, particularly in skill training. However, there was no significant improvement in knowledge learning. The findings provide foundational data for expanding AR/MR applications in medical education.