bluuebunny/crossref_metadata_2025_split huggingface dataset:
Structural Analysis Reveals the Substrate‐Binding Mechanism for the Expanded Substrate Specificity of Mutant meso‐Diaminopimelate Dehydrogenase
Authors: Liu Weidong , Guo Rey‐Ting , Chen Xi , Li Zhe , Gao Xiuzhen , Huang Chun‐Hsiang , Wu Qiaqing , Feng Jinhui , Zhu Dunming 
Published: March 2015

AbstractA meso‐diaminopimelate dehydrogenase (DAPDH) from Clostridium tetani E88 (CtDAPDH) was found to have low activity toward the D‐amino acids other than its native substrate. Site‐directed mutagenesis similar to that carried out on the residues mutated by Vedha‐Peters et al. resulted in a mutant enzyme with highly improved catalytic ability for the synthesis of D‐amino acids. The crystal structures of the CtDAPDH mutant in apo form and in complex with meso‐diaminopimelate (meso‐DAP), D‐leucine (D‐leu), and 4‐methyl‐2‐oxopentanoic acid (MOPA) were solved. meso‐DAP was found in an area outside the catalytic cavity; this suggested a possible two‐step substrate‐binding mechanism for meso‐DAP. D‐leu and MOPA each bound both to Leu154 and to Gly155 in the open form of CtDAPDH, and structural analysis revealed the molecular basis for the expanded substrate specificity of the mutant meso‐diaminopimelate dehydrogenases.
Sieving Effects in Electrical Double‐Layer Capacitors Based on Neat [Al(hfip)4]− and [NTf2]− Ionic Liquids
Authors: Roznyatovskaya Nataliya , Rupp Alexander B. A. , Tübke Jens , Krossing Ingo 
Published: March 2015

AbstractWe present an electrochemical investigation into ionic liquids (ILs) based on [Al(hfip)4]− and [NTf2]− anions as electrolytes in supercapacitors. The synthesis of [Al(hfip)4]− ILs was improved to minimize the water content for electrochemical measurements. Several electrodes with different pore sizes from micropores to macropores were prepared. Impedance and cyclic voltammetry studies of eight ILs were conducted with the electrodes and revealed that, despite their close‐to‐ideal transport properties, [Al(hfip)4]− ILs suffer from a sieving effect in the case of micropores, which leads to a sharp drop in capacitance compared with [NTf2]− ILs. When the influence of the size is abrogated at meso‐ or macroporous electrodes, the aluminate salts become competitive in terms of capacitance and show that, without a sieving effect, their basic properties in principal make them suitable electrolytes as well.
Binding Energies of the π‐Stacked Anisole Dimer: New Molecular Beam—Laser Spectroscopy Experiments and CCSD(T) Calculations
Authors: Řezáč Jan , Nachtigallová Dana , Mazzoni Federico , Pasquini Massimiliano , Pietraperzia Giangaetano , Becucci Maurizio , Müller‐Dethlefs Klaus , Hobza Pavel 
Published: March 2015

AbstractAmong noncovalent interactions, π–π stacking is a very important binding motif governed mainly by London dispersion. Despite its importance, for instance, for the structure of bio‐macromolecules, the direct experimental measurement of binding energies in π–π stacked complexes has been elusive for a long time. Only recently, an experimental value for the binding energy of the anisole dimer was presented, determined by velocity mapping ion imaging in a two‐photon resonant ionisation molecular beam experiment. However, in that paper, a discrepancy was already noted between the obtained experimental value and a theoretical estimate. Here, we present an accurate recalculation of the binding energy based on the combination of the CCSD(T)/CBS interaction energy and a DFT‐D3 vibrational analysis. This proves unambiguously that the previously reported experimental value is too high and a new series of measurements with a different, more sensitive apparatus was performed. The new experimental value of 1800±100 cm−1 (5.15±0.29 kcal mol−1) is close to the present theoretical prediction of 5.04±0.40 kcal mol−1. Additional calculations of the properties of the cationic and excited states involved in the photodissociation of the dimer were used to identify and rationalise the difficulties encountered in the experimental work.
Hierarchically Designed Three‐Dimensional Macro/Mesoporous Carbon Frameworks for Advanced Electrochemical Capacitance Storage
Authors: Yang Yanbing , Li Peixu , Wu Shiting , Li Xinyang , Shi Enzheng , Shen Qicang , Wu Dehai , Xu Wenjing , Cao Anyuan , Yuan Quan 
Published: March 2015

AbstractMesoporous carbon (m‐C) has potential applications as porous electrodes for electrochemical energy storage, but its applications have been severely limited by the inherent fragility and low electrical conductivity. A rational strategy is presented to construct m‐C into hierarchical porous structures with high flexibility by using a carbon nanotube (CNT) sponge as a three‐dimensional template, and grafting Pt nanoparticles at the m‐C surface. This method involves several controllable steps including solution deposition of a mesoporous silica (m‐SiO2) layer onto CNTs, chemical vapor deposition of acetylene, and etching of m‐SiO2, resulting in a CNT@m‐C core–shell or a CNT@m‐C@Pt core–shell hybrid structure after Pt adsorption. The underlying CNT network provides a robust yet flexible support and a high electrical conductivity, whereas the m‐C provides large surface area, and the Pt nanoparticles improves interfacial electron and ion diffusion. Consequently, specific capacitances of 203 and 311 F g−1 have been achieved in these CNT@m‐C and CNT@m‐C@Pt sponges as supercapacitor electrodes, respectively, which can retain 96 % of original capacitance under large degree compression.
Transition‐Metal‐Free Coupling Reaction of Vinylcyclopropanes with Aldehydes Catalyzed by Tin Hydride
Authors: Ieki Ryosuke , Kani Yuria , Tsunoi Shinji , Shibata Ikuya 
Published: March 2015

AbstractDonor–acceptor cyclopropanes are useful building blocks for catalytic cycloaddition reactions with a range of electrophiles to give various cyclic products. In contrast, relatively few methods are available for the synthesis of homoallylic alcohols through coupling of vinylcyclopropanes (VCPs) with aldehydes, even with transition‐metal catalysts. Here, we report that the hydrostannation of vinylcyclopropanes (VCPs) was effectively promoted by dibutyliodotin hydride (Bu2SnIH). The resultant allylic tin compounds reacted easily with aldehydes. Furthermore, the use of Bu2SnIH was effectively catalytic in the presence of hydrosilane as a hydride source, which established a coupling reaction of VCPs with aldehydes for the synthesis of homoallylic alcohols without the use of transition‐metal catalysts. In contrast to conventional catalytic reactions of VCPs, the presented method allowed the use of several VCPs in addition to conventional donor–acceptor cyclopropanes.
ChemInform Abstract: Formation and Stability of Gaseous Ternary Oxides of Group 14‐16 Elements and Related Oxides of Group 15 Elements: Mass Spectrometric and Quantum Chemical Study.
Authors: Kunkel Katerina , Milke Edgar , Binnewies Michael 
Published: March 2015

AbstractThe formation of the new compounds PbTeO3, PbTe2O5, Pb2TeO4, and Pb2Te2O6 is observed in the gas phase by heating a mixture of solid PbO and TeO2 at 1063 K using a mass‐spectrometric Knudsen‐cell method.
ChemInform Abstract: Zr4CuSb7 — A PbFCl‐Related Polyantimonide, and Structure Relations of Zirconium‐Transition Metal Polyantimonides.
Authors: Greiwe Magnus , Nilges Tom 
Published: March 2015

AbstractSingle crystals of Zr4CuSb7 are obtained by arc‐melting of the elements with 10 % Sb excess followed by annealing (evacuated quartz tubes, 1123 K, 3 d).
ChemInform Abstract: Strong Electron Hybridization and Fermi‐to‐Non‐Fermi Liquid Transition in LaCu3Ir4O12.
Authors: Greenblatt Martha , et al. et al. 
Published: March 2015

AbstractThe AA′3B4O12‐type perovskite LaCu3Ir4O12 is prepared by high pressure solid state reaction of a stoichiometric mixture of La2O3, CuO, Ir powder, and IrO2 (Pt capsule in MgO crucible, multianvil press, 9 GPa, 1523 K, 1 h).
ChemInform Abstract: Synthesis, Crystal Structure and Properties of a New Barium Calcium Borate, Ba2Ca2(B2O5)2.
Authors: Liu Lu , Zhang Fangfang , Pan Shilie , Lei Chen , Zhang Fangyuan , Dong Xiaoyu , Wang Zheng , Yu Hongwei , Yang Zhihua 
Published: March 2015

AbstractThe new title compound is synthesized by solid state reaction of stoichiometric mixtures of Ba(NO3)2, CaO, and H3BO3 (500 °C for 7 h followed by 900 °C for 72 h).
ChemInform Abstract: Synthesis and Characterization of a Novel Inorganic—Organic Hybrid Open‐Framework Zinc Phosphate with 16‐Ring Channels.
Authors: Wang Guo‐Ming , Li Jin‐Hua , Gao Cui‐Li , Zhang Jun‐Cheng , Zhang Xiao , Bao Zhen‐Zhen , Wang Ying‐Xia , Lin Jian‐Hua 
Published: March 2015

AbstractMicroporous (NH4) [Zn5(PO4)3(HPO4)2 (HAPIM)2]·(H2O) is solvothermally prepared in the presence of 1‐(3‐aminopropyl)imidazole (APIM) as structure‐directing agent using ZnO, H3PO4, APIM, MeOH, and H2O in the molar ratio 2:3.1:2:86.5:139 (autoclave, 160 °C, 6 d, 46% yield).
ChemInform Abstract: Cs2Hg3S4: A Low‐Dimensional Direct Bandgap Semiconductor.
Authors: Kanatzidis Mercouri G. , et al. et al. 
Published: March 2015

AbstractThe new title compound is prepared by slowly cooling a melted stoichiometric mixture of Hg and Cs2S4 (evacuated, carbon coated silica tube, 670 °C, 24 h).
ChemInform Abstract: Stereoconvergent Arylations and Alkenylations of Unactivated Alkyl Electrophiles: Catalytic Enantioselective Synthesis of Secondary Sulfonamides and Sulfones.
Authors: Choi Junwon , Martin‐Gago Pablo , Fu Gregory C. 
Published: March 2015

AbstractNickel‐catalyzed stereoconvergent Negishi arylations and alkenylations of racemic α‐bromosulfones and ‐sulfonamides are described.
ChemInform Abstract: Bicyclic Bridgehead Phosphoramidite (Briphos) Ligands with Tunable π‐Acceptor Ability and Catalytic Activity in the Rhodium‐Catalyzed Conjugate Additions.
Authors: Lee Ansoo , Ahn Seihwan , Kang Kyungjun , Seo Min‐Seob , Kim Yeonjoon , Kim Woo Youn , Kim Hyunwoo 
Published: March 2015

AbstractLigand BRI in combination with a rhodium catalyst gives the best results for the conjugate additions of N‐tosyl ketimines with arylboronic acids.
ChemInform Abstract: Transfer Hydrogenation of Ketones to Alkanes Using Tributylamine under Heterogeneous Pd/C Catalysis.
Authors: Kim Tae Gyun , Cho Chan Sik , Kim Young‐su 
Published: March 2015

AbstractThe Pd‐catalyzed transfer hydrogenation of aryl ketones with tributylamine leads to corresponding alkanes (II), whilst the similar reaction of dialkyl ketone (Ii) fails.
ChemInform Abstract: General Suzuki Coupling of Heteroaryl Bromides by Using Tri‐tert‐Butylphosphine as a Supporting Ligand.
Authors: Zou Yinjun , Yue Guizhou , Xu Jianwei , Zhou Jianrong Steve 
Published: March 2015

AbstractHigh yields are obtained within 5 minutes reaction time at room temperature.
ChemInform Abstract: Phosphine‐Free Tetradentate Salicylaldimine Ligand Complexed with Palladium: First Application in Heck Reactions.
Authors: Kalhapure Rahul S. , Govender Thirumala , Akamanchi Krishnacharya G. 
Published: March 2015

AbstractAdvantages of the introduced method are mild reaction conditions, short reaction times and low palladium loading.
ChemInform Abstract: Amidation of Esters with Amino Alcohols Using Organobase Catalysis.
Authors: Caldwell Nicola , Campbell Peter S. , Jamieson Craig , Potjewyd Frances , Simpson Iain , Watson Allan J. B. 
Published: March 2015

AbstractBEMP is an efficient catalyst for reactions of amino alcohols with dimethyl carbonate and a variety of methyl esters.
ChemInform Abstract: A General, Regiospecific Synthetic Route to Perfluoroalkylated Arenes via Arenediazonium Salts with RFCu(CH3CN) Complexes.
Authors: Jiang Dong‐Fang , Liu Chao , Guo Yong , Xiao Ji‐Chang , Chen Qing‐Yun 
Published: March 2015

AbstractArylamines can be converted into perfluoroalkylated arenes (III) under mild conditions.
ChemInform Abstract: Copper‐Free Direct C—H Trifluoromethylation of Acetanilides with Sodium Trifluoromethanesulfinate.
Authors: Wu Mingxi , Ji Xinfei , Dai Wenpeng , Cao Song 
Published: March 2015

AbstractLanglois reagent (II) is tested under conditions A) in the reactions with 4‐substituted acetanilides bearing either electron‐donating or electron‐withdrawing groups.
ChemInform Abstract: Mild, Stereoselective, and Highly Efficient Synthesis of N‐Acylhydrazones Mediated by CeCl3·7H2O in a Broad Range of Solvents.
Authors: dos Santos Filho Jose Mauricio 
Published: March 2015

AbstractThe catalyst is active in various protic and aprotic solvents including water, but EtOH is the medium of choice.
ChemInform Abstract: Highly Enantioselective Reactions of Cyclohexanone and β,γ‐Unsaturated α‐Keto Ester: The Tuning of Chemo‐Selectivities by Secondary and Primary Amine Catalysts.
Authors: Wei Jianwei , Guo Wengang , Zhou Xin , Du Xin , Liu Yan , Li Can 
Published: March 2015

AbstractAmphiphilic imidazole based secondary and primary amine catalysts show different chemoselectivity in the title reaction.
ChemInform Abstract: Copper‐Catalyzed Cascade Transformation of O‐Propargylic Oximes with Sulfonyl Azides to α,β‐Unsaturated N‐Acylamidines.
Authors: Zhang Dong , Nakamura Itaru , Terada Masahiro 
Published: March 2015

AbstractThe title reaction involves the intramolecular attack of the oxime group to the in situ generated ketenimine moiety, followed by cleavage of the N—O bond.
ChemInform Abstract: A Concise Synthesis of 2‐(2‐Hydroxyphenyl)acetonitriles (III) via the o‐Quinone Methides Generated from 2‐(1‐Tosylalkyl)phenols (I).
Authors: Wu Bo , Gao Xiang , Chen Mu‐Wang , Zhou Yong‐Gui 
Published: March 2015

AbstractThe title compounds (III) can be conveniently transformed into benzofuranones (IV).
ChemInform Abstract: Pd‐Free Sonogashira Coupling: One Pot Synthesis of Phthalide via Domino Sonogashira Coupling and 5‐exo‐dig Cyclization.
Authors: Dhara Shubhendu , Singha Raju , Ghosh Munmun , Ahmed Atiur , Nuree Yasin , Das Anuvab , Ray Jayanta K. 
Published: March 2015

AbstractPhthalides are synthesized using a short and efficient methodology under mild conditions.
ChemInform Abstract: Palladium‐Catalyzed Regioselective 5‐exo‐O‐Cyclization/Oxidative Heck Cascades from o‐Alkynylbenzamides and Electron‐Deficient Alkenes.
Authors: Madich Youssef , Alvarez Rosana , Aurrecoechea Jose M. 
Published: March 2015

AbstractA regioselectivity switch between 5‐exo‐dig and 6‐endo cyclization / Heck‐type coupling cascades of o‐alkynylbenzamides and electron‐deficient alkenes is triggered by the choice of both palladium catalyst and base.
ChemInform Abstract: Direct Synthesis of Diverse 2‐Aminobenzo[b]thiophenes via Palladium‐Catalyzed Carbon—Sulfur Bond Formation Using Na2S2O3 as the Sulfur Source.
Authors: Hou Chuanwei , He Qian , Yang Chunhao 
Published: March 2015

Abstract2‐Bromoarylacetonitriles are directly converted into 2‐amino and 2‐dimethylamino substituted benzothiophenes using the odorless sulfur source Na2S2O3.
ChemInform Abstract: Autotandem Catalysis: Synthesis of Pyrroles by Gold‐Catalyzed Cascade Reaction.
Authors: Ueda Hirofumi , Yamaguchi Minami , Kameya Hiroshi , Sugimoto Kenji , Tokuyama Hidetoshi 
Published: March 2015

AbstractNew addition‐cyclization sequence for the synthesis of multisubstituted pyrroles is reported.
ChemInform Abstract: The “One‐Pot” Synthesis of 4,5‐Dihydrobenzo[g]indole and Its 1‐Vinyl Derivative from 1‐Tetralone, Hydroxylamine, and Dichloroethane in the System KOH—DMSO.
Authors: Ivanov A. V. , Barnakova V. S. , Mikhaleva A. I. , Trofimov B. A. 
Published: March 2015

AbstractAn environmentally‐friendly, fire‐safe, and explosion‐proof route to previously difficult accessible benzoindole derivatives is developed.
ChemInform Abstract: Synthesis of Substituted 2‐Aminoimidazoles via Pd‐Catalyzed Alkyne Carboamination Reactions. Application to the Synthesis of Preclathridine Natural Products.
Authors: Zavesky Blane P. , Babij Nicholas R. , Wolfe John P. 
Published: March 2015

AbstractNew strategy for the construction of 2‐aminoimidazoles via the Pd‐catalyzed alkyne carboamination of tosyl‐protected N‐propargyl guanidines and aryl triflates is reported.
ChemInform Abstract: A Fast Way to Fluorescence: A Fourfold Domino Reaction to Condensed Polycyclic Compounds.
Authors: Tietze Lutz F. , Eichhorst Christoph , Hungerland Tim , Steinert Markus 
Published: March 2015

AbstractA fourfold domino Sonogashira/double‐carbopalladation/C—H activation reaction allows the synthesis of polycyclic compounds that show strong fluorescence activity.
ChemInform Abstract: Application and Scope of Schreiber′s Gold(I)‐Catalyzed α‐Pyrone Synthesis to Ring A Aromatic Podolactones.
Authors: Sanchez‐Larios Eduardo , Giacometti Robert D. , Hanessian Stephen 
Published: March 2015

AbstractThe title reaction of diynes of type (I) and (III) is examined to give α‐pyrones in good to moderate yields.
ChemInform Abstract: Interrupted Imino‐Nazarov Cyclization of 1‐Aminopentadienyl Cation and Related Cascade Process.
Authors: William Ronny , Wang Siming , Ding Feiqing , Arviana Elise Nerissa , Liu Xue‐Wei 
Published: March 2015

AbstractThe Lewis acid catalyzed condensations of aldehyde (I) with secondary aniline derivatives involve the formation of an oxyallyl intermediate which undergoes intramolecular arene trapping to form tricyclic indoline‐fused cyclopentanones (VI) and (VII).
ChemInform Abstract: Mn(III)‐Mediated Reactions of 2‐Isocyanobiaryl with 1,3‐Dicarbonyl Compounds: Efficient Synthesis of 6‐Alkylated and 6‐Monofluoro‐Alkylated Phenanthridines.
Authors: Cao Jia‐Jia , Wang Xiang , Wang Shun‐Yi , Ji Shun‐Jun 
Published: March 2015

AbstractAn efficient method for the synthesis of the title phenanthridines by reactions of 2‐isocyanobiaryl with 1,3‐dicarbonyl compounds is presented.
ChemInform Abstract: Copper‐Catalyzed Aerobic Oxidative Dehydrogenation for Conversion of 2‐(alkylthio)‐1,4‐Dihydropyrimidines to 2‐(alkylthio)Pyrimidines.
Authors: Phan Nguyen Huu Trong , Sohn Jeong‐Hun 
Published: March 2015

AbstractFor the presented approach no further additives like oxidants, acids, or bases are required.
ChemInform Abstract: Asymmetric Synthesis of N,O‐Heterocycles via Enantioselective Iridium‐Catalyzed Intramolecular Allylic Amidation.
Authors: Zhao Depeng , Fananas‐Mastral Martin , Chang Mu‐Chieh , Otten Edwin , Feringa Ben L. 
Published: March 2015

AbstractThe products are obtained in high yields and excellent enantioselectivity.
ChemInform Abstract: Room Temperature Alkynylation of H‐Phosphi(na)tes and Secondary Phosphine Oxides with Ethynylbenziodoxolone (EBX) Reagents.
Authors: Chen C. Chun , Waser Jerome 
Published: March 2015

AbstractThe alkynylation of the title organophosphorus compounds with silyl, aryl, or alkyl ethynyl‐benziodoxolone derivatives proceeds under metal‐free, mild, and aerobic conditions.
ChemInform Abstract: A Recyclable Biphasic System for Stereoselective and Easily Handled Hydrochalcogenations.
Authors: Tidei Caterina , Sancineto Luca , Bagnoli Luana , Battistelli Benedetta , Marini Francesca , Santi Claudio 
Published: March 2015

Abstract(Z)‐configured vinyl selenides and sulfides are prepared from alkynes and the corresponding dichalcogenides.
ChemInform Abstract: Two New Sesquiterpenoids from the Rhizomes of Curcuma xanthorrhiza.
Authors: Zhang Chun‐Mei , Fan Pei‐Hong , Li Min , Lou Hong‐Xiang 
Published: March 2015

Abstractisolation and structure elucidation of two new sesquiterpenoids, zedoaridol (I) and bisaboladiene derivative (II), together with six known compounds
ChemInform Abstract: Iridoid Glycosides from the Roots of Scrophularia ningpoensis Hemsl.
Authors: Zhu Ling‐Juan , Qiao Cheng , Shen Xiu‐Yu , Zhang Xue , Yao Xin‐Sheng 
Published: March 2015

AbstractThe two new iridoid glycosides scrophularianoids A (I) and B (II) are isolated from the roots of Scrophularia ningpoensis.
ChemInform Abstract: Chemical and Genetic Studies on Hybrid of Ligularia subspicata and Ligularia cyathiceps Collected in Yunnan Province of China.
Authors: Shimizu Anna , Watanabe Shizuka , Hanai Ryo , Okamoto Yasuko , Tori Motoo , Gong Xun , Kuroda Chiaki 
Published: March 2015

AbstractFive Ligularia samples are analyzed and twenty compounds, including two new compounds (I) and (II), are isolated.
ChemInform Abstract: Synthesis of Indazole Motifs and Their Medicinal Importance: An Overview
Authors: Gaikwad Digambar D. , Chapolikar Archana D. , Devkate Chandrashekhar G. , Warad Khandu D. , Tayade Amit P. , Pawar Rajendra P. , Domb Abraham J. 
Published: March 2015

AbstractReview: 139 refs.
Fluorine in Drug Design: A Case Study with Fluoroanisoles
Authors: Xing Li , Blakemore David C. , Narayanan Arjun , Unwalla Ray , Lovering Frank , Denny R. Aldrin , Zhou Huanyu , Bunnage Mark E. 
Published: March 2015

AbstractAnisole and fluoroanisoles display distinct conformational preferences, as evident from a survey of their crystal structures. In addition to altering the free ligand conformation, various degrees of fluorination have a strong impact on physicochemical and pharmacokinetic properties. Analysis of anisole and fluoroanisole matched molecular pairs in the Pfizer corporate database reveals interesting trends: 1) PhOCF3 increases log D by ∼1 log unit over PhOCH3 compounds; 2) PhOCF3 shows lower passive permeability despite its higher lipophilicity; and 3) PhOCF3 does not appreciably improve metabolic stability over PhOCH3. Emerging from the investigation, difluoroanisole (PhOCF2H) strikes a better balance of properties with noticeable advantages of log D and transcellular permeability over PhOCF3. Synthetic assessment illustrates that the routes to access difluoroanisoles are often more straightforward than those for trifluoroanisoles. Whereas replacing PhOCH3 with PhOCF3 is a common tactic to optimize ADME properties, our analysis suggests PhOCF2H may be a more attractive alternative, and greater exploitation of this motif is recommended.
From Epoxidized Linseed Oil to Bioresin: An Overall Approach of Epoxy/Anhydride Cross‐Linking
Authors: Pin Jean‐Mathieu , Sbirrazzuoli Nicolas , Mija Alice 
Published: March 2015

AbstractBiorenewable resources can be used as green monomers to design tailored structures for formulations that can play an important role as functional materials. The choice of optimal structures depends on the targeted properties and applications. This work focuses on the elaboration of biobased materials with toughened mechanical properties based on epoxidized linseed oil. This result was obtained by an overall approach of cross‐linking process, that is, starting with the optimal choice of hardeners and finally favoring the side reactions of polymerization. Therefore, the anionic alternating copolymerization of epoxide with mono‐ and dianhydrides was investigated to tailor the parameters that led to maximal conversions and properties. The obtained highly cross‐linked networks perform well, as demonstrated by good impact strengths, high glass transition temperatures, and excellent thermal stability, which opens up the possibility of using these emergent materials for industrial applications.