bluuebunny/crossref_metadata_2025_split huggingface dataset:
Carbonate reservoir characterization and permeability modeling using Machine Learning ـــ a study from Ras Fanar field, Gulf of Suez, Egypt
Authors: Khalid Mostafa S. , Mansour Ahmed S. , Desouky Saad El-Din M. , Afify Walaa S. M. , Ahmed Sayed F. , Elnaggar Osama M. 
Published: July 2024

AbstractPredicting facies and petrophysical properties along and between wells is challenging in carbonate reservoir modeling. In the Nullipore carbonate reservoir, Ras Fanar field, depositional and long-term diagenetic processes result in a high degree of heterogeneity and complex distribution of facies, which in turn affect the reservoir quality. This provides a significant obstacle to building accurate geological models. This study integrates thin sections, routine core analyses, and well logging data to overcome such difficulties and model the Nullipore carbonate facies and permeability. The detailed petrographic analysis revealed the existence of seven microfacies in the reservoir, which are summed up into three facies associations (FAs), each of which represents a specific reservoir rock type (RRT): (1) supratidal FA, (2) intertidal FA, and (3) shallow subtidal FA. The three FAs were correlated with the gamma-ray logs to create facies logs for the studied wells, which were further populated via the Truncated Gaussian Simulation method. Cross-validation was used to evaluate the model's accuracy. The analysis of the available core data infers that the three RRTs are prospective and have a wide permeability distribution. However, RRT3 constitutes the best reservoir quality. The sedimentological analysis revealed that the long-term diagenetic events, involving the dolomitization of limestone and the dissolution of allochems have a major role in improving the pore connectivity and permeability of the reservoir. Fracture characterization discloses that fractures play a significant role in fluid storage and migration. Three Machine Learning (ML) models, including Adaptive boosting (AdaBoost), Gradient Boosting (GB), and Extreme Gradient Boosting (XGB), were developed to integrate the RRTs, porosity, and permeability to improve permeability prediction. Statistical analysis revealed that the XGB model outperforms other models and exhibits the highest prediction performance. The present study provides further insights into the characterization and modeling of facies and permeability of complex carbonate reservoirs. It can be applied in similar geological settings to better interpretation of depositional and diagenetic controls on reservoir quality assessment and aid in the field development plan.
Influence of LVAD Cannula Outflow Graft Flow Rate and Location on Fluid-Particle Interactions and Thrombi Distribution: A Primary Numerical Study
Authors: Li Longyan , Shi Li , Tan Xiao , Zhao Yixia 
Published: July 2024

AbstractA left ventricular assist device (LVAD) supports hemodynamics in heart failure patients. To deepen the understanding of hemodynamic changes and the movement of thrombi in the aorta, we examined three distinct LVAD blood flow rates across two implantation sites using the theory of computational fluid dynamics. Our findings revealed the complex dynamics of blood flow during cardiac systole under various scenarios. We also analyzed thrombi residence time and flow probabilities into aortic branches. Simulation results indicate that thrombi distribution in the aorta is significantly influenced by the location of the LVAD outflow graft and the flow rate. When the LVAD outflow graft is implanted into the ascending aorta, higher flow rates may reduce the risk of cerebral thrombosis. However, lower flow rates may reduce the risk of cerebral thrombosis while it is implanted into the descending aorta. The study may offer valuable insights into the LVAD implantation about the risk of cerebrovascular embolism.
Graphical Abstract
Exploring the Impact of Steam Explosion Pretreatment on the Binding Characteristics of Coal-Biomass Briquettes: A Study on Lignocellulose Type and Fibre Morphology
Authors: van der Westhuizen Lodewicus , Rorke Daneal C.S. , Görgens Johann F. 
Published: July 2024

Abstract
The urgency to shift from coal to renewable energy sources drives the need for innovative solutions. Steam exploded lignocellulose acting as both binder and fuel in coal-briquetting presents a pathway for this transition whilst utilizing waste coal-fines. However, the applicability of different industrially relevant feedstocks and their specific binding mechanism is unknown. In this study we assess the impact of treatment severity and explosion pressure on fibre properties and briquette tensile compressive strength (TCS) across four feedstocks (sugarcane bagasse (SCB), corn stover (CS), black wattle (BW), and pine). Lignocellulose was steam exploded at severities ranging from 3.53 to 4.71 and physical modifications due to explosion pressure was isolated by conducting explosive decompressions at pressures ranging from 3 to 22.5 bar. Briquettes, prepared using 18% by mass steam exploded lignocellulose as a binder, were quantified for TCS and results showed that as particle aspect ratio increased, so did TCS, regardless of lignocellulose type. For SCB, CS, and BW, high explosion pressure and low to moderate severity (3.5–3.8) produced the highest aspect ratios and, consequently, highest TCS (1288, 1181, 905 kPa respectively). However, at high severity and pressure, a reduction in aspect ratio was observed and, subsequently, TCS. Pine required high severity and pressure to produce barely acceptable briquette TCS (364 kPa), due to its low aspect ratio. Physical modification of fibre aspect ratio during steam explosion therefore played a crucial role in its binding performance in coal-briquettes and the relative success of SCB, CS and BW indicate that there are significant resources of lignocellulose available for this technology and allow for widespread industrial application.

Graphical Abstract
Ataxin-2: a powerful RNA-binding protein
Authors: Li Lulu , Wang Meng , Huang Lai , Zheng Xiaoli , Wang Lina , Miao Hongming 
Published: July 2024

AbstractAtaxin-2 (ATXN2) was originally discovered in the context of spinocerebellar ataxia type 2 (SCA2), but it has become a key player in various neurodegenerative diseases. This review delves into the multifaceted roles of ATXN2 in human diseases, revealing its diverse molecular and cellular pathways. The impact of ATXN2 on diseases extends beyond functional outcomes; it mainly interacts with various RNA-binding proteins (RBPs) to regulate different stages of post-transcriptional gene expression in diseases. With the progress of research, ATXN2 has also been found to play an important role in the development of various cancers, including breast cancer, gastric cancer, pancreatic cancer, colon cancer, and esophageal cancer. This comprehensive exploration underscores the crucial role of ATXN2 in the pathogenesis of diseases and warrants further investigation by the scientific community. By reviewing the latest discoveries on the regulatory functions of ATXN2 in diseases, this article helps us understand the complex molecular mechanisms of a series of human diseases related to this intriguing protein.
Integrative analysis reveals the potential prognostic roles and immunological values of unc-5 netrin receptor A (UNC5A) in glioma
Authors: Qian Wenbo , Zhang Lei , Zhang Fenglin , Ye Jingliang , Wan Zhiping , Chen Huairui , Luo Chun 
Published: July 2024

Abstract
Background
UNC5A had been reported to play crucial roles in multiple cancers. However, little was known about the associations among UNC5A and glioma. Therefore, we first combined scRNA-seq, proteomics, as well as bulk RNA-seq in order to investigate UNC5A’s functions in gliomas.

Methods
Online databases provided scRNA-seq, proteomics, as well as bulk RNA-seq data on UNC5A in gliomas. The following procedures were conducted in order: QRT-PCR, Norman chart, gene set enrichment analysis (GSEA), and univariate/multifactor Cox regression analyses. We further explored the associations among UNC5A and tumor immunity.

Results
By comparing gliomas with normal tissues, the TCGA dataset showed a significantly reduced expression of UNC5A, which was also confirmed by GSE50161, GSE4290, and QRT-PCR findings (p < 0.05). In both the TCGA and CGGA datasets, gliomas patients with low-UNC5A expression would have poorer overall survival (OS) prognoses (p < 0.05). ScRNA-seq analysis by the CancerSEA online website presented that UNC5A had a low expression in various glioma clusters and significantly associated with six functional states. Moreover, UNC5A might be a reliable independent biomarker of OS in gliomas patients (p < 0.05). Based on the results of GSEA, UNC5A might be connected to three significant pathways in gliomas. We also successfully created a Norman chart to assess the OS prognoses of these patients. Additionally, in aspects of tumor immunity, the infiltration levels of immune cells in LGG, the immune cell pathways, tumor immune microenvironment, as well as immune checkpoints in both LGG and GBM were revealed to be significantly influenced by UNC5A (p < 0.05).

Conclusions
UNC5A was found to have prognostic and immunological significance in gliomas, offering patients with gliomas new treatment options.
Degradation of a novel magnesium alloy-based bioresorbable coronary scaffold in a swine coronary artery model
Authors: Torii Sho , Yamamoto Akiko , Yoshikawa Ayako , Lu Linhai , Sasaki Makoto , Obuchi Shoko , Wada Akira , Tsukamoto Hideo , Nakazawa Gaku 
Published: July 2024

AbstractThe objective of the study is to investigate the safety, feasibility, and degradation profile of a novel Mg alloy-based bioresorbable coronary scaffold (JFK-PRODUCT BRS) with thin struts (110 μm). Polymer- or Mg alloy-based BRSs have not replaced nondegradable metal stents because of the higher prevalence of scaffold thrombosis and restenosis in clinical practice; these poor clinical outcomes were due to inadequate scaffold designs, including thick struts (more than 150 μm) and their inappropriate degradation processes. Fourteen healthy pigs received 17 JFK-PRODUCT BRSs in the coronary arteries and were sacrificed at 1, 6, 12, 18, and 26 months after implantation. Angiography, optical coherence tomography, microfocus X-ray computed tomography (µCT), scanning electron microscopy with energy-dispersive X-ray spectrometry (SEM–EDX), and histopathological evaluation were performed. The JFK-PRODUCT had a median percent late recoil of 11.28% at 1 month. The µCT observation confirmed that scaffold discontinuity reached 64.8% at 12 months with increased scaffold inner area thereafter, suggesting artery positive remodeling. The inflammation was mild, peaked at 18 months, and decreased thereafter. The SEM–EDX analysis demonstrated gradual degradation of the scaffold with formation of inorganic deposits, presumed to be calcium phosphates. It also revealed the disappearance of calcium phosphates at 26 months, achieving almost complete replacement of the scaffold by biocomponents. The current study demonstrated the safety and feasibility of JFK-PRODUCT with a lower acute recoil rate despite its thin struts. The scaffolds were almost completely disappeared at 26 months after implantation.
Graphical abstract
The effects of drought and salinity on KS and RAW managerial coefficients in the efficient water management in maize farms
Authors: Zargar Yaghoubi Faramarz , Sarai Tabrizi Mahdi , Mohammadi Torkashvand Ali , Esfandiari Mehrdad , Ramezani Etedali Hadi 
Published: July 2024

AbstractThis study aimed to investigate the simultaneous effects of drought and salinity on irrigation management coefficients in maize farms. A three-year field research was conducted in the form of a 3 × 3 factorial experiment with a randomized complete block design and three replications from 2020 to 2022 in a maize farm, in Aliabad Fashafoye, Qom province, Iran. The applied treatments included three levels of salinity (S0 = 1.8, S1 = 5.2, and S2 = 8.6 dS/m) and three levels of irrigation (W0 = 100%, W1 = 75%, and W2 = 50% of field capacity). Evapotranspiration stress coefficient (KS) due to W0S1 and W0S2 treatments was (0.975 and 0.934), (0.974 and 0.932), and (0.962 and 0.935) in 2020, 2021, and 2022, respectively. According to the results, KS decreased by increasing the salinity level of irrigation water, so a 1-unit increase in salinity level above the tolerance threshold of the crop to salinity decreased KS by 0.78 and 1.76% for S1 and S2, respectively. Moreover, each percent of volumetric moisture decrease from field capacity decreased KS by 5.9 and 13.3% in W1 and W2, respectively. Also, with the increase in the intensity of the stresses, the readily available water (RAW) of treatments decreased. The sole application of salinity stress decreased the decreasing slope of RAW by 3.2%, while the application of both stresses resulted in the decreasing slopes of 4.9, 5.7, and 7.8% at the salinity levels of S0, S1, and S2, respectively, compared to the control. The findings of this study show that the accurate estimation of crop evapotranspiration and RAW can help to improve the irrigation schedule, and the amount of irrigation water used is less than in non-stress conditions due to the reduction of total evapotranspiration and less water uptake in environmental stresses in maize farms.
Therapie des schmerzhaften Fußes mit ärztlicher Akupunktur
Authors: Schmid Oskar A. 
Published: July 2024

ZusammenfassungDie Behandlung schmerzhafter Fußdeformitäten ist eine Herausforderung, insbesondere wenn Dysästhesien mit Funktionsverlust und Schmerzen einhergehen.Bei Fußschmerzen müssen die Segmente L4, L5 und S1 sowohl lokal berücksichtigt werden als auch die Segmente C6 bis C8 in der oberen Extremität, die aufgrund segmentaler Verbindungen als zusätzliche Behandlungsbereiche der Akupunktur genutzt werden können.Die segmentale und neurophysiologisch basierte Behandlung mit ärztlicher Akupunktur ist eine weitere wertvolle Komponente der konservativen medizinischen Therapie bei schmerzhaften Fußdeformitäten.
Investigating structural property of human hair by using infrared free electron lasers
Authors: Kawasaki Takayasu , Nagase Atsushi , Hayakawa Ken , Teshima Fumitsuna , Tanaka Kiyohisa , Zen Heishun , Irizawa Akinori , Sakai Takeshi , Hayakawa Yasushi 
Published: July 2024

AbstractIntense infrared (IR) rays can heat matters and evaporate waters thermally. One of the possible applications will be hair dryer, although the irradiation effects of IR rays on the hair have not been fully explored. In this study, we first examined the interaction of IR rays at various wavelengths from 3.0 µm (near IR) to 90 µm (far IR) with the surface structure of human hair by using IR free electron lasers (FELs). IR-FEL is an accelerator-based pico-second pulse laser, and the feature is the wavelength-tunability with the high-photon density. When one thread of hair was irradiated by the FEL of 6–7 mJ energy at 60 µm, the cleavage occurred, and the morphological destruction was observed on scanning-electron microscopy images after the irradiations at 70 µm and 6.1 µm (amide I). Synchrotron-radiation infrared microspectroscopy showed that those FEL irradiations decreased a shoulder band at 1710 cm−1 that corresponds to carboxyl group in melanin or fatty acids and increased absorption intensity at 500–600 cm−1. On the contrary, the FEL at 90 µm little changed either the surface morphology or the infrared absorption spectra. Interestingly, near-IR FELs at 3.0–3.5 µm induced bending of a hair, and 2D mapping of protein secondary conformations revealed that β-sheet was more increased than the other conformations on the surface of the bending area even at low pulse energy (1–3 mJ). As a result, the structural damage of the hair was least at 90 µm, which implies an ideal wavelength for drying hair mildly.
Pupal diapause in Hypocosmia pyrochroma (Lepidoptera: Pyralidae), a biological control agent for Dolichandra unguis-cati (Bignoniaceae)
Authors: Dhileepan Kunjithapatham 
Published: July 2024

AbstractCats claw creeper leaf-tying moth Hypocosmia pyrochroma (Lepidoptera: Pyralidae) enter pupal diapause in the soil from middle of autumn (April), in response to declining photoperiod. Proportion of larvae entering pupal diapause increased with decreasing Daily Solar Radiation (DSR), and all larvae completing development in winter under low DSR entered pupal diapause. Under natural photoperiod, adults emerged from pupal diapause, from late spring (October) to middle of summer (January), with peak adult emergence in late spring (November) and early summer (December). Pupae did not undergo diapause when the entire development (eggs and all larval instars) occurred under prolonged photoperiod (14 L:10D). However, it was not possible to terminate the pupal diapause either by prolonging photoperiod or by increasing the temperate regimes. Based on larval incidence in the field it is proposed that H. pyrochroma is a bivoltine species with overlapping generations.
Prevalence of and factors associated with anxiety, depression and post-traumatic stress disorder among Sudan ebolavirus disease survivors and family members, Uganda, January 2023: a cross-sectional study
Authors: Agaba Brian , Nelly Hellen Naiga , Wanyana Mercy Wendy , Zalwango Jane Frances , Simbwa Brenda , Akunzirwe Rebecca , Zavuga Robert , Kawungezi Peter Chris , Zalwango Marie Gorreti , Migamba Stella Martha , Kadobera Daniel , Bulage Lilian , Migisha Richard , Ario Alex Riolexus , Harris Julie R. 
Published: July 2024

Abstract
Background
Communities affected by Ebola disease (EBOD) may face resulting increases in mental health disorders. We evaluated the prevalence of and factors associated with mental health disorders among persons affected by the 2022 Sudan virus disease (SVD) outbreak in Uganda.

Methods
We conducted a cross-sectional study among SVD survivors and family members of survivors and fatal cases from 15–31 January 2023. We included only laboratory-confirmed SVD survivors and family members who lived with or cared for confirmed SVD patients during their illness. The Hospital Anxiety and Depression Scale was used to evaluate anxiety and depression. The post-traumatic stress disorder (PTSD) checklist for the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition was used to evaluate PTSD. Modified Poisson regression was used to determine factors associated with each mental health disorder.

Results
We enrolled 54 survivors and 82 family members; median age was 30 years (range, 15–73) and 54% were female. The prevalence of anxiety (55%) and depression (50%) was higher than PTSD (17%). The prevalence of all mental health disorders was similar between survivors and family members. Household size was associated with both anxiety and PTSD. Number of SVD deaths in the household was associated with depression.

Conclusion
Approximately two-thirds of SVD survivors and family members of patients in the 2022 outbreak in Uganda had ≥ 1 mental health disorders shortly after the outbreak ended. Strengthening mental health services during and after Ebola virus outbreaks for survivors and family members of patients may enhance the quality of outbreak response.
Life cycle assessment of manual toothbrush materials
Authors: Mazur Marta , Ruggeri Marco , Ottolenghi Livia , Scrascia Andrea , Gobbi Laura , Vinci Giuliana 
Published: July 2024

Abstract
Background
A manual toothbrush is an indispensable tool for promoting and maintaining oral health worldwide but given the non-biodegradable and non-recyclable thermoplastic materials from which it is made, it cannot be considered free of threats to the environment. Therefore, also in light of the World Dental Federation's goals to implement and initiate policies for sustainable dentistry, this study evaluates the sustainability of two materials most used for manual toothbrush bristles, namely nylon, and silicone.

Objectives
The objective is to investigate the optimal solution to reduce the environmental impact of toothbrushes, and how the environmental impact would change if only the brush head was changed instead of the entire toothbrush.

Methods
Life Cycle Assessment and Carbon Footprint were used. Four manual toothbrushes with nylon bristles, and a handle in polypropylene with/without silicone parts (N1, N2, N3, N4) and two manual toothbrushes, with silicone bristles, but one with polypropylene handle only (Si1), the other with polypropylene handle and silicone parts (Si2) were evaluated.

Results
A toothbrush with silicone bristles is more sustainable than one with nylon bristles in all 18 impact categories, with average values of − 14%. In addition, eliminating only the brush head instead of the entire toothbrush could result in savings of 4.69 × 10‒3 kg CO2 eq per toothbrush. Therefore, based on the results of this study and to meet Dentistry's need to reduce its environmental impact, the ideal toothbrush should be lightweight, with less superfluous material, and with less impactful materials such as silicone instead of nylon.

Conclusions
The concluding indications for improving the sustainability of toothbrushes are therefore: (i) eliminate the amount of superfluous material; (ii) develop lighter models; and (iii) develop models in which only the brush head is replaced rather than the entire toothbrush.
The Impact of an Antarctic Circumpolar Current Meander on Air‐Sea Interaction and Water Subduction
Authors: Vilela‐Silva Felipe , Bindoff Nathaniel L. , Phillips Helen E. , Rintoul Stephen R. , Nikurashin Max 
Published: July 2024

AbstractStanding meanders along the Antarctic Circumpolar Current (ACC) have been shown to be regions of elevated eddy variability, meridional heat transport, and vertical exchange. In this study, we investigate the influence of a standing meander south of Australia on air‐sea heat fluxes, upper ocean structure, and subduction in the 1/10° ACCESS‐OM2 ocean‐sea ice model forced by the JRA55 atmospheric reanalysis. We track the model's Subantarctic and Polar Fronts based on their jet and water mass structure, and produce composites of thermodynamical and dynamical properties of the meander in relaxed and flexed states. The standing meander induces trough‐to‐crest variations in surface heat flux, mixed layer depth (MLD), wind stress curl, vertical velocity, and subduction. At the crests, the ocean loses heat and the mixed layer is deeper; at the troughs, the ocean gains heat and the mixed layer is shallower. Wind stress curl, vertical velocity, and subduction change sign on entering and exiting crests and troughs. Vertical velocity due to the curvature of the meander is an order of magnitude larger than Ekman vertical velocity. The poleward excursion of Polar Front meander crests extends subduction to Antarctic Intermediate Water density classes. Finally, flexing of the meander enhances both air‐sea exchange and vertical velocity. The results show that standing meanders of the ACC influence the distribution and magnitude of air‐sea fluxes of heat and momentum and exchange between the surface and interior ocean.
Implications of Variability and Trends in Coastal Extreme Water Levels
Authors: Sweet William V. , Genz Ayesha S. , Menendez Melisa , Marra John J. , Obeysekera Jayantha 
Published: July 2024

AbstractProbabilities of coastal extreme water levels (EWLs) are increasing as sea levels rise. Using a time‐dependent statistical model on tide gauge data along U.S. and Pacific Basin coastlines, we show that EWL probability distributions also shift on an annual basis from climate forcing and long‐period tidal cycles. In some regions, combined variability (>15 cm) can be as large or larger than the amount of sea level rise (SLR) experienced over the past 30 years and projected over the next 30 years. Considering SLR and variability by 2050 at a location like La Jolla, California suggests a moderate‐level (damaging) flood today with a 50‐year return level (2% annual chance) would occur about 3–4 times a year during an El Nino nearing the peak of the nodal tide cycle. If interannual variability is overlooked, SLR related impacts could be more severe than anticipated based solely upon decadal‐scale projections.