bluuebunny/crossref_metadata_2025_split huggingface dataset:
Phytochemical, Minerals and Antimicrobial Evaluation of Trianthema portulacastrum (aizoaceae) Leaf extract
Authors: Okolo S C , Habila J D , Hamisu I 
Published: February 2025

The leaf extracts of the plant was analyzed for its phytochemical, mineral and antimicrobial activities using the standard method. The Phytochemical constituent revealed the presence of tannins in all the solvent system used for extraction. Alkaloids and phenol were present in dichloromethane, ethyl acetate, methanol and aqueous extract but absent in ethanol extract. Flavonoids, cardiac glycoside and saponins were present in aqueous and ethanol extract. Terpenoids was absent in aqueous but present in the other solvent used. The proximate composition revealed carbohydrate has the highest percentage content of 21.24%, protein: 21.10%, Fibre: 18.40%, Ash: 17.82% while lipid and moisture content are 11.94% and 9.5% respectively. The mineral composition in the leaf showed the contents (mg/g) as in order of Ca: 7.3303mg/g>K: 2.3297mg/g>Na: 1.3327mg/g>Mg: 0.7427mg/g>Fe: 0.6234mg/g>Mn: 0.2344mg/g>Cu: 0.0555mg/g>Zn: 0.0435mg/g>Cr: 0.0330mg/g>Pb: 0.0198mg/g>Ni: 0.0054>Cd: 0.0022mg/g The PPT/DCM/HP, FILT/DCM/HP, ETOA/HP and MTH/HP extract showed sensitivity in stephlococcus aureus, FILT/DCM/HP and MTH/HP are sensitive in Meth. resist staph aureous and Acinetobacter sp. The zone of inhibition against the test microorganisms occurred in the four (4) extract at 20mm, 20mm, 20mm and 22mm for staphylococcus aureus and the extract, PPT/DCM/HP(24mm), FILT/DCM/HP(20mm) and MTH/HP) in streptococcus pneumonia and PPT/DCM/HP(27mm), FILT/DCM/HP(20mm) and MTH/HP(20mm) for Acinetobacter sp. The results shows that the leaf extract plays significant role in the body metabolic system.
Faisabilité de la production du coton biologique au Cameroun : essai de fertilisation organique
Authors: Oumarou Yakouba , Magouedek Desiré Kesseo Todou , Wassouo Felix Alain , Dapsia Jackson Djakbe , Mohamadou Alidou 
Published: February 2025

Description du sujet: Au Cameroun, le coton est produit selon un système de culture conventionnel, caractérisé par l’apport systématique d’intrants chimiques. Avec la prise de conscience croissante des risques que ces produits peuvent générer pour l'environnement, des arguments sont de plus en plus avancés en faveur d’une production biologique du coton.
Objectifs: L’objectif de cette étude est d’identifier les fertilisants organiques utilisables dans le système de culture biologique du coton.
Méthodes: L’étude a été conduit dans deux localités de la zone cotonnière du Cameroun. Le dispositif expérimental était en blocs de Fisher avec cinq (5) traitements (Compost ; Tourteau de neem ; Terre de parc à bétail ; NPK 20-10-10 + Urée à 46 % de N et le Témoin sans fertilisation). L’essais a été répété trois fois. Les paramètres de croissance (diamètre au collet, taille de la plante et nombre de branches fructifères) et de rendement (nombre moyen de capsules par plante et rendement en coton-graine) ainsi que les caractéristiques physico-chimiques du sol ont été mesurés.
Résultats: Les résultats obtenus ont montré que sur les deux sites, le pH du sol qui été modérément acide a évolué vers la neutralité. Les taux du carbone organique, de la matière organique, la teneur en azote, en magnésium, en potassium et la somme des bases échangeables ont été aussi améliorées. Par ailleurs, les fertilisants organiques utilisés ont significativement et positivement influencé les paramètres de croissance mesurés et les paramètres de rendement sur les deux sites. Parmi ces fertilisants, c’est le tourteau de Neem qui a induit les meilleurs résultats avec des rendements de 1355,57 kg/ha contre 712,68 kg/ha sur la parcelle témoin à Dolla et 3377,10 kg/ha contre 1955,56 kg/ha sur la parcelle témoin à Zokok-Ladéo.
Conclusion: Ces résultats suggèrent que ces fertilisants organiques et plus particulièrement le Tourteau de Neem peuvent être utilisés dans le système de culture biologique du coton au Cameroun.
The Effects of Full-Scale Military Conflicts on the Labour Market: Impact on Employment and Unemployment
Authors: Zub Mariia , Atamanska Svitlana , Turenko Vitalii , Krymchak Liudmyla , Rebryk Petro 
Published: February 2025

Objective: The study aims to determine the relationships between military conflict and the labour market and assess its impact on the socio-economic situation of the population. The object of the study is the impact of military conflict on the labour market. It means that the study is focused on examining and analysing how military events and conflicts affect employment and unemployment levels.

Theoretical Framework: In this study, the main concepts and theories that underpin the research are the socio-economic impacts of military conflicts on the employment market. These frameworks provide a solid basis for understanding the context of the investigation and developing effective socio-economic recovery strategies.

Method: The research is based on statistical data analysis, allowing for objective conclusions about the consequences of military conflict on the labour market. Comparative analysis: comparing the labour market before and after the military conflict and using economic modelling to forecast possible consequences of the military conflict on the labour market and to develop socio-economic recovery strategies.

Results and Discussion: The results show that military conflict significantly affects employment and unemployment levels, which can exacerbate socio-economic problems in the conflict zone. The study's practical significance lies in considering these factors when developing employment and socio-economic development policies in conflict conditions. The results of the study can be helpful for government agencies, international organisations, and public organisations involved in social protection and labour market development issues in conflict conditions.
Hybrid Work Models, Employee Productivity: The Mediating Role of Digital Transformation at Jordans it Sector in the Context of (SDGs)
Authors: Al-Tarawneh Ramzi M. , Al-sheyyab Yasser Mohammad , Laila Hanadi Lutfi Abu 
Published: February 2025

Purpose: This study aims to investigate the impact of hybrid work model in Employee Productivity. Exploring the mediating role of digital transformation in enhancing this impact in the Context of Sustainable Development Goals (SDGs).

Design/methodology/approach: Utilizing a quantitative-analytical approach. using a specially designed survey. A simple random sample consists of 153 managers at JITC.

Findings: The findings reveal that the hybrid work model, encompassing remote-first, occasional office presence, and office-first remote allowed arrangement, significantly effects employee productivity. Additionally, digital transformation partially enhances the effects of hybrid work model in employee productivity. Hhybrid work model does not significantly influence digital transformation. Digital transformation, however, has a significantly effects on employee productivity at JITC in the Context of Sustainable Development Goals (SDGs).

Research Limitation: The results of this study must be viewed very carefully, bearing in mind some limitations. Whether it is related to the study population, which is a very homogeneous professional community, limited to one country, Jordan, is probably difficult to accurately describe, in addition to some limitations of this type of applied research and related to methodology. All required measurements of error and fit described in the relevant literature applied in this research have been made, and we can never be confident enough in the strength of conclusions and in minimizing errors and random effects.

Research implications: This study is distinguished by the importance of its subject, dimensions, and the specificity of its community. It provides a general framework that enriches the Jordanian library in particular, and the Arab and global libraries in general. This study serves as a starting point for further future research, offering a new research perspective and a comprehensive understanding of the link between the components of the hybrid work model and their impact on employee productivity, while emphasizing the role of digital transformation technologies in enhancing job productivity levels.

Practical implications: The practical implications lie in the importance of its results and their impact on organizational trends and decision-makers, including managers and practitioners. The study guides them towards integrating hybrid work models into their operations, adopting policies that support this approach, and taking organizational measures to enhance employee productivity. Additionally, the study highlights the importance of using digital technologies and communication systems, as well as data exchange and analysis, to achieve sustainable improvements in job productivity and overall organizational performance.
Economic Strengthening After the COVID-19 Pandemic Disaster Through Internet E-Commerce: SDG Study for Economic Growth After Pandemic Disaster
Authors: Aziz Muhammad Hilmy , Ariadi Septi , Arif Lukman 
Published: February 2025

Objective: This study aims to explore government strategies for economic strengthening post-COVID-19 by leveraging the internet and emphasizing the urgency of developing independent e-commerce systems as a foundation for a digital economy.

Theoretical Framework: The study draws upon concepts of digital transformation, Industry 4.0 technologies, and Society 5.0, which integrate technological innovation with societal needs. The framework emphasizes digital literacy, advanced technology adoption, and regulatory strategies to foster sustainable economic growth In Sustainable Development Goals (SDGs) area.

Method: A qualitative approach using Focus Group Discussions (FGD) was employed to gather insights from various stakeholders. This method facilitated an in-depth understanding of social and economic dynamics relevant to internet utilization and e-commerce development.

Results and Discussion: The findings highlight five critical strategies for the government: improving digital services, adopting cutting-edge technologies (AI, Big Data, IoT), enhancing human resource digital literacy, integrating industrial modernization, and encouraging financial technology. Additionally, the study underscores the need for an independent e-commerce system, named SADE (E-Commerce Trade Application System), to empower local MSMEs and reduce dependence on foreign platforms.

Research Implications: The results provide actionable insights for policymakers to design inclusive digital frameworks and for MSMEs to embrace digital tools for market expansion. The study emphasizes the need for digital literacy initiatives to enable equitable access to digital transformation benefits.

Originality/Value: This research bridges technology, economy, and policy perspectives to propose innovative solutions for economic recovery. The unique focus on independent e-commerce development offers a practical roadmap for achieving digital economic resilience and advancing Society 5.0 principles.
Taurine But Not Proline Protects Cells from Cisplatin, Activates p21, and Fibronectin Expression
Authors: Greenberg Michael , Gladych-Macioszek Aleksandra , Klupczynska – Gabryszak Agnieszka , Plewa Szymon , Matysiak Jan , Zaborowski Mikolaj , Iwanicki Marcin , Centeno Daniel 
Published: February 2025

Amino acids are macromolecules forming proteins. This makes them essential for life, as proteins are needed for many cell functions. Amino acids that are not part of a protein, but rather freely floating, are called free amino acids (FAAs). Cells can use FAAs to support metabolism, growth, and survival. We have previously determined the intracellular concentration of various FAAs in cells isolated from ovarian cancer (OC) malignant fluids. Taurine and proline were among the most enriched free intracellular amino acids in these patient cell samples. In contrast to malignant samples, a tissue culture model representing OC precursor cells contained significantly less intracellular taurine and proline. Taurine but not proline supplementation induced p21 activation, fibronectin deposition, cell adhesion, and resistance to DNA-damaging agent cisplatin. Our data suggest the possibility that accumulation of intracellular taurine but not proline can protect cells from cisplatin and this protection is associated with the activation of p21 and fibronectin protein expression.
ANALISIS REGRESI LINIER BERGANDA PENGARUH UMUR, JARAK MRT, DAN TOKO PADA HARGA RUMAH
Authors: ARISTAWIDYA MUHAMMAD VITO , Syahfajar L.M Aznur , Rahayu Woro Isti , Mustaqim Kiki 
Published: February 2025

Penelitian ini bertujuan untuk memberikan gambaran yang lebih komprehensif tentang faktor-faktor yang mempengaruhi harga rumah di Xindian District, New Taipei City, Taiwan. Penelitian ini akan menganalisis data tentang umur rumah, jarak ke stasiun MRT, jumlah toko terdekat, dan harga rumah. Statistik deskriptif akan digunakan untuk menggambarkan distribusi dan karakteristik variabel-variabel tersebut. Analisis regresi linear berganda akan digunakan untuk menguji pengaruh variabel independen (umur rumah, jarak ke stasiun MRT, dan jumlah toko terdekat) terhadap variabel dependen (harga rumah). Hasil analisis diharapkan dapat menghasilkan persamaan regresi linear yang menunjukkan hubungan antara variabel independen dan dependen. Koefisien regresi akan menunjukkan kekuatan dan arah hubungan antara variabel-variabel tersebut. Uji statistik akan digunakan untuk menentukan signifikansi statistik dari hasil analisis. Hasil yang didapatkan berupa data aktual dan data prediksi yang divisualisasikan dengan plot. Dilakukan pencarian koefisien variabel -0,253 untuk harga rumah, -0,005 untuk jarak ke MRT dan 1,297 untuk jumlah toko serta didapatkan hasil uji pemodelan adalah 0,541 untuk skor R-Square.
INTEGRАTED SОCIАL SERVICES FОR FAMILIES АND CHILDREN IN RISKY SITUАTIОNS IN THE REPUBLIC ОF MОLDОVА THRОUGH THE LENS ОF SUSTАINАBLE DEVELОPMENT GОАLS
Authors: CОRОBАN Cristina 
Published: February 2025

The аrticle presents integrаted sоciаl services fоr children аs аn essentiаl element in the prоtectiоn аnd well-being оf vulnerаble children in the Republic оf Mоldоvа. Integrаted sоciаl services tаke а cооrdinаted аpprоаch, cоmbining interventiоns frоm heаlth, educаtiоn, sоciаl prоtectiоn аnd legаl suppоrt. They аddress the cоmplex needs оf children аt risk, including sepаrаted children, children аffected by pоverty аnd children with disаbilities. The Sustаinаble Develоpment Gоаls (SDGs) relevаnt fоr Mоldоvа frоm the perspective оf integrаted sоciаl services аre: erаdicаting pоverty (SDG 1), ensuring heаlth аnd well-being (SDG 3), ensuring quаlity educаtiоn (SDG 4), reducing inequаlities (SDG 10); prоmоting justice аnd inclusiоn (SDG 16) аnd strengthening pаrtnerships (SDG 17). The SDGs fоrm а cоmprehensive set thаt ensure sustаinаble develоpment in Mоldоvа аnd cоntribute tо imprоving the quаlity оf life including fоr peоple in vulnerаble grоups.
Investigations of the Hybrid Effects of the Operational Parameters in the Radial Forging Process Based on the Validation of the Hardness Test
Authors: Darki Saeed , Raskatov Evgeniy Yurevich 
Published: February 2025

In this study, considering all the parameters in radial forging and a three-dimensional model has been simulated using the finite element method. By implementing an elastoplastic state for the specimen tube, parameters such as friction type, residual stress distribution, effective strain distribution, material flow velocity and its effect on the neutral plate and the distribution of force in the die have been studied and analyzed. The effects of angle on the quality and characteristics of the specimen and the longevity of the die have also been obtained. Experimental results have been used to confirm the accuracy of the simulation. The results of the hardness test after forging were compared with the simulation results. Good agreement between the results indicates the accuracy of the simulation in terms of hardness. Therefore, this validation allows confirming the other obtained results for the analysis and prediction of various components in the forging process. After the validation and confirmation of the results through the hardness test, the hardness distribution was obtained by considering temperature changes and the effective strain on the specimen.

Received: 28 October 2024 | Revised: 2 December 2024 | Accepted: 8 January 2025

Conflicts of Interest
The authors declare that they have no conflicts of interest to this work.

Data Availability Statement
Data available on request from the corresponding author upon reasonable request.

Author Contribution Statement
Saeed Darki: Conceptualization, Methodology, Software, Formal analysis, Investigation, Resources, Data curation, Writing - original draft, Writing - review & editing, Visualization, Project administration. Evgeniy Yurevich Raskatov: Software, Validation, Resources, Supervision.
Novel biotargets of colorectal cancer peritoneal metastasis
Authors: Gu Ye , Liu Qiang , Li LeLe , Li Lingyun , Xu Dongchao , Zheng Liyun , Xie Lu , Cheng Sile , Shen Hongzhang , Jie Yanbing , Zhou Yifeng , Yang Jianfeng , Jin Hangbin , Zhang Xiaofeng 
Published: February 2025

IntroductionPeritoneal metastasis often predicts advanced progression and a poor prognosis in colorectal cancer (CRC). However, peritoneal metastases are extremely difficult to predict or diagnose by routine diagnostic methods.Material and methodsIn this study, a microarray containing 30 samples from peritoneal metastasis and their matched CRC primaries obtained during cytoreductive surgery were compared to take a long hard look at all the options on the significant differentially expressed genes. The potential interactions and mechanisms of these expressed genes in promoting peritoneal metastasis were analyzed and studied by multiple bioinformatics analysis.ResultsThe results suggested that the functions of these genes are closely related to immune response and cytokine activity. Additionally, the top 10 core genes’ correction with the leukocyte infiltration and serum cytokine profiles were identified and may be expected to become diagnostic and therapeutic targets of peritoneal metastasis in CRC.ConclusionsThe expression of IL-6, IL-10 and IL-17 in plasma and their correlation with leukocyte infiltration are proven potential diagnostic, prognostic, and therapeutic biomarkers for peritoneal management of CRC.
Split cord malformation – a simple, current classification based on CT and MRI neuroimaging studies
Authors: Kleinrok Jadwiga , Kleinrok Krzysztof , Popiela Tadeusz Jan 
Published: February 2025

The aim of this paper is to present the currently used classification of split cord malformation. Split cord malformation (SCM) is a developmental defect arising during neurulation, resulting in abnormal neural tube development, with the formation of a division within the spinal cord and dural sac. The terms diastematomyelia and diplomyelia are used in the literature to describe this defect. In 1992, Pang proposed the term SCM to describe all dysraphic spinal cord defects and classified them into type I and type II, depending on the nature of the sagittal septum within the spinal canal and the presence or absence of a divided dural sac. SCM type I includes cases with a bony septum and a divided dural sac, while SCM type II includes cases without a divided dural sac but with a fibrous septum present. Depending on the type of defect, and the location and extent of the split, the condition is accompanied by neurological symptoms of varying localisation and severity. As symptoms may worsen with the child’s growth, surgical intervention to remove the septum is usually necessary. In this article, the authors present the defect based on literature data, describe the current terminology regarding the defect and associated anomalies, and present a set of features that should be assessed to classify lesions.
Determinasi Kompetensi, Pelatihan Dan Pengembangan Karir Terhadap Kinerja Karyawan Pada Badan Penghubung Provinsi X di Jakarta
Authors: Purwito Purwito , Satrio Hendri Budi , Perkasa Didin Hikmah 
Published: February 2025

Penelitian ini bertujuan untuk mengetahui dan menganalisis pengaruh Kompetensi, Pelatihan dan Pengembangan Karir terhadap Kinerja Karyawan (Studi kasus pada Badan Penghubung Provinsi X di Jakarta). Desain penelitian menggunakan metode kuantitatif kausal. yaitu mengetahui pengaruh antar variable yang diteliti. Alat pengumpulan data mengunakan kuisioner yang disebarkan kepada Pegawai pada Badan Penghubung Provinsi X di Jakarta. Populasi yang diteliti pada penelitian ini sebanyak 60 Pegawai, sedangkan sampel yang digunakan sebanyak 60 Pegawai menggunakan teknik sampling jenuh. Metode Analisis data dalam penelitian ini menggunakan SEM PLS dengan bantuan software untuk olah data Smart PLS, adapun tahapan-tahapan yang akan dilakukan dalam pegelolaan data sebagai berikut, melalui pengujian outer model, inner model dan uji hipotesis. Tahap pertama membuat instrument penelitian pada masing-masing variable yang akan diteliti. Tahap kedua menguji instrument variable Kompetensi, Pelatihan, Pengembangan Karir dan Kinerja Karyawan. Hasil penelitian menunjukkan bahwa Kompetensi tidak berpengaruh, sedangkan Pelatihan dan Pengembangan Karir berpengaruh terhadap Kinerja Karyawan Badan Penghubung Provinsi X di Jakarta.
Kata kunci : Kompetensi, Pelatihan, Pengembangan Karir, Kinerja Karyawan
Relationship between Personal Support and Performance of Students Enrolled in Distance Learning in Selected Public Universities in Kenya and Senegal
Authors: Ouko-Ouambo Leya Amonde , Aseey Anne Achieng , Kisimbii Johnbosco Mutuku 
Published: February 2025

Distance learning has emerged as a pivotal mode of education post-COVID-19, addressing challenges such as geographical and infrastructural limitations. This study evaluates the influence of personal support on the academic performance of students enrolled in distance learning at the University of Nairobi (UoN) in Kenya and the University of Cheikh Anta Diop (UCAD) in Senegal. The study was grounded in Moore's Transactional Distance Theory, which defines transactional distance as the gap between two parties in a learning relationship. The study used a descriptive research design and a sample of 240 students drawn from a target population of 12,022 students. The researcher used purposive sampling to select the two universities for the study. In addition, the researcher used proportionate sampling to select students from each faculty, and simple random sampling technique to select students from each faculty. The researcher used standardized questionnaires to collect data from the participants. The questionnaires were administered with the help of research assistants. The researcher applied both descriptive and inferential statistics in data analysis. The researcher also used regression analysis, goodness-of-fit evaluation, and correlation analysis. The data analysis outcomes were presented using tables and graphs. The research identified a significant positive correlation between personal support and learner performance, with UoN exhibiting an R-squared value of 62% and UCAD 52%. Regression analysis revealed that a unit increase in personal support led to a 0.78 performance improvement at UoN and 0.72 at UCAD. The study underscores the importance of robust personal support systems, including mentorship, counselling, and academic guidance, in enhancing the effectiveness of distance learning. It was established that there exist a positive and significant relationship between personal support and learner performance. Recommendations include strengthening institutional frameworks and exploring longitudinal impacts of support mechanisms.