bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: [Te8][NbOCl4]2 Containing an Infinite Chain‐Like {[Te—Te—Te—(Te5)]2+}n Polycation.
Authors: Feldmann Claus , Freudenmann Dominic 
Published: January 2013

AbstractTranslucent black crystals of the title compound are obtained from mixtures of Te, NbCl5, and NbOCl3 in the ionic liquid [bmim]Cl (Ar filled glass ampules, 423 K, 14 d; 30% yield).
ChemInform Abstract: Na3Cd3B(PO4)4: A New Noncentrosymmetric Borophosphate with Zero‐Dimensional Anion Units.
Authors: Shi Yunjing , Pan Shilie , Dong Xiaoyu , Wang Ying , Zhang Min , Zhang Fangfang , Zhou Zhongxiang 
Published: January 2013

AbstractThe title compound is synthesized by solid state reaction of Na2CO3, CdO, H3BO3, and NH4H2PO4 in the molar ratio 1.5:3:1:4 (sealed silica tube, 680 °C, 3 d).
ChemInform Abstract: Chemical and Photochemical Functionality of the First Molecular Bismuth Vanadium Oxide.
Authors: Tucher Johannes , Nye Leanne C. , Ivanovic‐Burmazovic Ivana , Notarnicola Antonio , Streb Carsten 
Published: January 2013

AbstractThe first molecular bismuth vanadium oxide cluster compound H3 [{Bi(dmso)3}4V13O40] ·≈4DMSO is synthesized by addition of an aqueous Bu4NOH solution to a hot solution of Bi(NO3)3 and (Bu4N)3[H3V10O28] in DMSO/2% H2O (80 °C, 1 h, 91% yield).
ChemInform Abstract: Enantio‐ and Diastereoselective Oxidation of N‐Alkylimines Using Chiral α‐Bromonitriles and Hydrogen Peroxide System.
Authors: Tka Najeh , Kraiem Jamil , Hassine Bechir Ben 
Published: January 2013

AbstractThe system chiral α‐bromonitriles/hydrogen peroxide is examined for the enantio‐ and diastereoselective oxidation of N‐alkylimines in aqueous medium at room temperature yielding the corresponding oxaziridines.
ChemInform Abstract: Highly Diastereoselective Construction of Acyclic Systems with Two Adjacent Quaternary Stereocenters by Allylation of Ketones.
Authors: Takeda Takeshi , Yamamoto Masanori , Yoshida Satoshi , Tsubouchi Akira 
Published: January 2013

AbstractUnsymmetrical ketones and allyltitanocenes generated by the desulfurizative titanation of γ,γ‐disubstituted allyl phenyl sulfides give the corresponding alcohols.
ChemInform Abstract: Diversity Oriented Approach to Polycyclic Compounds Through the Diels—Alder Reaction and the Suzuki Coupling.
Authors: Kotha Sambasivarao , Misra Shilpi , Srinivas Venu 
Published: January 2013

AbstractA method for preparation of small, drug‐like molecules based on indane, tetraline and isoquinoline scaffolds is developed starting from 1,2‐bis(bromomethyl)tetrahalobenzenes using Diels—Alder reactions, alkylations and Suzuki couplings.
ChemInform Abstract: Rapid and Efficient Access to Secondary Arylmethylamines.
Authors: Fleury‐Bregeot Nicolas , Raushel Jessica , Sandrock Deidre L. , Dreher Spencer D. , Molander Gary A. 
Published: January 2013

AbstractThe title compounds are prepared by the Suzuki—Miyaura cross‐coupling of secondary ammoniomethyltrifluoroborates (III) with aryl/heteroaryl bromides in the presence of aminobiphenyl palladium precatalyst PPA.
ChemInform Abstract: Copper(II)—Acid‐Cocatalyzed Intermolecular Substitution of Electron‐Rich Aromatics with Diazoesters.
Authors: Tayama Eiji , Ishikawa Moe , Iwamoto Hajime , Hasegawa Eietsu 
Published: January 2013

AbstractVarious N‐functionalized anilines such as (Ib)—(Ie) and (IV) or electron‐rich alkoxybenzenes (VI) undergo a Cu(II)‐catalyzed electrophilic aromatic substitution with diazoesters in the presence of acidic catalysts under optimized conditions.
ChemInform Abstract: Synthesis of 2,4‐Bis(aryloxy)‐1,5‐diarylpentane‐1,5‐diones by Base‐Mediated Tandem Reaction.
Authors: Xie Ye‐Xiang , et al. et al. 
Published: January 2013

AbstractA simple process is developed for the double nucleophilic substitution of dichloromethane with aryloxymethyl aryl ketones to give functionalized pentanediones in good yields.
ChemInform Abstract: Synthesis of N‐(1‐Methyl‐1H‐indol‐3‐yl)methyleneamines and 3,3‐Diaryl‐4‐(1‐methyl‐1H‐indol‐3‐yl)azetidin‐2‐ones as Potential Antileishmanial Agents.
Authors: Singh Girija S. , Al‐kahraman Yasser M. S. A. , Mpadi Disah , Yasinzai Masoom 
Published: January 2013

AbstractNovel azetidine‐2‐ones (III), obtained via Staudinger cycloaddition, are screened for their antileishmanial activity against Leishmania major.
ChemInform Abstract: A Modular and Scalable One‐Pot Synthesis of Polysubstituted Furans.
Authors: Fournier Jeremy , Arseniyadis Stellios , Cossy Janine 
Published: January 2013

AbstractThis one‐pot, four‐step sequence consists of Pd‐catalyzed decarboxylative allylic alkylation followed by Cope rearrangement, nucleophilic addition and dehydration.
ChemInform Abstract: 1,4‐Addition of an Aryllithium Reagent to Diethyl Ketomalonate. Scalable Synthesis of Ethyl 1‐(Hydroxymethyl)‐1,3‐dihydroisobenzofuran‐1‐carboxylate.
Authors: Rocke Benjamin N. , Conn Edward L. , Eisenbeis Shane A. , Ruggeri Roger B. 
Published: January 2013

AbstractThe title compound (IV) is prepared on a large scale.
ChemInform Abstract: Regioselective Thorpe—Ziegler Cyclization of 3‐O‐Alkylated Thiophenes; Access to Aminothieno[3,2‐b]furans and Aminothieno[3,4‐b]furans.
Authors: Gadais Charlene , Hesse Stephanie , Kirsch Gilbert 
Published: January 2013

AbstractIt is demonstrated that base promoted intramolecular condensation occurs preferentially on the adjacent nitrile group rather than at an ester or at a ketone substituent.
ChemInform Abstract: Enantioselective Organo‐SOMO Cycloadditions: A Catalytic Approach to Complex Pyrrolidines from Olefins and Aldehydes.
Authors: Jui Nathan T. , Garber Jeffrey A. O. , Finelli Fernanda Gadini , MacMillan David W. C. 
Published: January 2013

AbstractA new method to rapidly generate pyrrolidines is accomplished by using commercially available or easily preparable starting materials and catalysts.
ChemInform Abstract: A New Series of Bisbenzimidazole Derivatives: Synthesis, Antitumor Activity and Low Toxicity on PBMC.
Authors: Wang Xiu‐Jun , Wang Qing‐He , Liu Chao , Li Wei , Wang Jian , Yang Na , Cheng Mao‐Sheng 
Published: January 2013

AbstractA new series of bisbenzimidazole derivatives (VI) is designed and synthesized.
ChemInform Abstract: Synthesis and Evaluation of 4‐(Substituted styryl/alkenyl)‐3,5‐bis(4‐hydroxyphenyl)‐isoxazoles as Ligands for the Estrogen Receptor.
Authors: Haddad Terra , Gershman Rachel , Dilis Robert , Labaree David , Hochberg Richard B. , Hanson Robert N. 
Published: January 2013

Abstract4‐(Substituted styryl/alkenyl)‐3,5‐bis(4‐hydroxyphenyl)‐isoxazoles of type (III) and (VII) are prepared and evaluated as ligands for the estrogen receptor‐alpha (ERα) The 4‐(4‐hydroxy‐styryl) derivative (VII) displays binding properties similar to those of the previously described pyrazole class of ER ligands, indicating that the ERα‐LBD tolerates the presence of the added vinyl group at the 4‐position of the isoxazole ring.
ChemInform Abstract: Asymmetric Synthesis of Highly Enantioenriched 2‐Substituted Piperidines and 6‐Substituted Piperidine‐2‐ones by a Combination Enantioselective Hydrazone Allylation with Ring Closing Metathesis.
Authors: Piao Fengnu , Mishra Mithilesh Kumar , Jang Doo Ok 
Published: January 2013

AbstractAn efficient method for the synthesis of the title compounds is developed for a variety of substrates.
ChemInform Abstract: Synthesis, Characterization, and Antimicrobial Evaluation of Quinoline‐Oxadiazole‐Based Azetidinone Derivatives.
Authors: Dodiya Amit M. , Shihory Niraj R. , Desai N. C. 
Published: January 2013

AbstractCompounds (III), combining biologically relevant quinoline, oxadiazole and azetidinone structural units in one molecule, show moderate to excellent antibacterial and antifungal activities.
ChemInform Abstract: Synthesis of 2‐(Hetero)arylthieno[2,3‐b] or [3,2‐b]Pyridines from 2,3‐Dihalopyridines, (Hetero)arylalkynes, and Na2S. Further Functionalizations.
Authors: Peixoto Daniela , Begouin Agathe , Queiroz Maria‐Joao R. P. 
Published: January 2013

AbstractA simple, general, and efficient methodology for the synthesis of the title compounds is described for the first time.
ChemInform Abstract: Ligand‐Based Design, Synthesis, and Pharmacological Evaluation of 3‐Methoxyquinoxalin‐2‐carboxamides as Structurally Novel Serotonin Type‐3 Receptor Antagonists.
Authors: Mahesh Radhakrishnan , Devadoss Thangaraj , Dhar Arghya Kusum , Venkatesh Sudali Muthu , Mundra Sourabh , Pandey Dilip Kumar , Bhatt Shvetank , Jindal Ankur Kumar 
Published: January 2013

AbstractNew carboxamides are investigated for their 5‐HT3 receptor antagonisms.
ChemInform Abstract: Synthesis and Herbicidal Activity of 2‐(Substituted phenoxyacetoxy)alkyl‐5,5‐dimethyl‐1,3,2‐dioxaphosphinan‐2‐one Containing Fluorine.
Authors: Wang Wei , He Hong‐Wu , Zuo Na , Zhang Xin , Lin Ji‐Sheng , Chen Wei , Peng Hao 
Published: January 2013

AbstractAll the title dioxaphosphinanone derivatives (I) (17 examples) exhibit moderate to good herbicidal activities.
Phase 2 study of preoperative radiation with concurrent capecitabine, oxaliplatin, and bevacizumab followed by surgery and postoperative 5‐fluorouracil, leucovorin, oxaliplatin (FOLFOX), and bevacizumab in patients with locally advanced rectal cancer: ECOG 3204
Authors: Landry Jerome C. , Feng Yang , Cohen Steven J. , Staley Charles A. , Whittington Richard , Sigurdson Elin Ruth , Nimeiri Halla , Verma Udit , Prabhu Roshan S. , Benson Al Bowen 
Published: January 2013

AbstractBACKGROUND:Recent studies have demonstrated the feasibility of combining oxaliplatin with 5‐fluorouracil (5‐FU) or capecitibine and radiation therapy. The addition of bevacizumab to chemotherapy improves overall survival for metastatic disease. We initiated a phase 2 trial to evaluate preoperative capecitabine, oxaliplatin, and bevacizumab with radiation therapy followed by surgery and postoperative 5‐FU, leucovorin, oxaliplatin (FOLFOX) and bevacizumab for locally advanced rectal cancer.METHODS:Fifty‐seven patients with resectable T3/T4 rectal adenocarcinoma were enrolled. Preoperative treatment was capecitabine (825 mg/m2 twice daily from Monday to Friday), oxaliplatin (50 mg/m2 weekly), bevacizumab (5 mg/kg on days 1, 15, 29), and radiation therapy (50.4 Gy). Surgery was performed by 6 weeks after neoadjuvant therapy. Beginning 8 to 12 weeks after surgery, patients received FOLFOX plus bevacizumab (5 mg/kg) every 2 weeks for 12 cycles.RESULTS:Fifty‐four of 57 enrolled patients were eligible. Forty‐nine (91%) patients completed preoperative therapy and underwent surgery. Nine patients (17%; 90% confidence interval, 9%‐27%) achieved pathologic complete response. Thirty‐two patients (59%) experienced pathologic tumor downstaging, and 53% and 15% of patients experienced worst grade 3 and grade 4 acute toxicity, respectively. Forty‐seven percent of patients who underwent surgery experienced a surgical complication.CONCLUSIONS:The primary endpoint of a 30% pathologic complete response rate was not reached; however, the majority of patients experienced pathologic downstaging with this regimen. Increased wound‐healing delays and complications may have been related to the addition of bevacizumab, oxaliplatin, or both. Continued observation of these patients will establish the long‐term morbidity and efficacy of this combined modality approach. Cancer 2013. © 2012 American Cancer Society.
Photo‐active Cobalt Cubane Model of an Oxygen‐Evolving Catalyst
Authors: Symes Mark D. , Lutterman Daniel A. , Teets Thomas S. , Anderson Bryce L. , Breen John J. , Nocera Daniel G. 
Published: January 2013

AbstractA dyad complex has been constructed as a soluble molecular model of a heterogeneous cobalt‐based oxygen‐evolving catalyst (Co‐OEC). To this end, the Co4O4 core of a cobalt‐oxo cubane was covalently appended to ReI photosensitisers. The resulting adduct was characterised both in the solid state (by X‐ray diffraction) and in solution using a variety of techniques. In particular, the covalent attachment of the ReI moieties to the Co4O4 core promotes emission quenching of the ReI photocentres, with implications for the energy and electron transduction process of Co‐OEC‐like catalysts.
Sleep apnoea syndrome and 10‐year cardiovascular risk in females with type 2 diabetes: relationship with insulin secretion and insulin resistance
Authors: Hermans Michel P. , Ahn Sylvie A. , Mahadeb Yovan P. , Rousseau Michel F. 
Published: January 2013

AbstractBackgroundObstructive sleep apnoea syndrome (OSAS) is a risk factor for type 2 diabetes mellitus (T2DM) and promotes cardiovascular events, especially in men. The prevalence of sleep apnoea and its association with microvascular and macrovascular diseases and glycaemic control are poorly documented in T2DM women.MethodsA total of 305 T2DM women were sleep apnoea diagnosed through (hetero)anamnesis, Epworth's score, oximetry and polysomnography. Sleep apnoea[+] (n = 25) were compared with sleep apnoea[−] (n = 280) regarding cardiovascular risk factors, glucose homeostasis, micro/macrovascular complications and the United Kingdom Prospective Diabetes Study (UKPDS) 10‐year risk.ResultsMean (1 SD) age was 66 (12) years, diabetes duration 15 (9) years, sleep apnoea prevalence 8.2% and metabolic syndrome 86%. There were no differences in age, diabetes duration, education, smoking and blood pressure between groups. Sleep apnoea[+] had significantly higher values of body mass index, waist, relative/absolute fat, conicity, visceral fat (all p < 0.0001) and lower skeletal muscle (p = 0.0008). The sleep apnoea[+] group was more insulin resistant [homeostasis model assessment (HOMA S): 37 (20)% versus 59 (44)%; p < 0.0001] and had lesser residual insulin secretion (HOMA B × S: 20 (12)% versus 30 (19)%; p = 0.0006), increased hyperbolic product loss (p = 0.0442) and poorer glycaemic control (HbA1c 69 (12) versus 62 (13) mmol mol−1; p = 0.0099). All atherogenic dyslipidaemia components and inflammatory markers were worsened in sleep apnoea[+]. Women with sleep apnoea had higher UKPDS risk of CAD: 18 (11)% versus 12 (10)% (p = 0.0136). Prevalent micro/macrovascular complications were not different between groups.ConclusionsSleep apnoea, a frequent comorbidity of T2DM women, is associated with central fat, atherogenic dyslipidaemia, inflammation, worsening β‐cell function, poorer glycaemic control and coronary artery disease risk. Sleep apnoea may increase residual vascular risk for microvascular and macrovascular events in T2DM women. Copyright © 2013 John Wiley & Sons, Ltd.
Synthesis, Structure, and Tungsten NMR Characterization of {SbW9O33}9–{Mo2O2S2}2+ Sandwich‐Like Polyoxothiometalates
Authors: Pilette Marie‐Anne , Floquet Sébastien , Marrot Jérôme , Sécheresse Francis , Cadot Emmanuel 
Published: January 2013

AbstractThe reaction of {SbW9O33}9– with {Mo2O2S2}2+ has been studied. The {SbW9O33}{Mo2O2S2} products are labile in solution and very sensitive to experimental conditions. Two new hybrids, {Mo2O2S2}‐containing tungstoantimonate anions, namely [(SbW9O33)2(Mo2O2S2)3]12– and [K(SbW9O33)2(Mo2O2S2)WO(H2O)]11–, have been fully characterized in the solid state and in solution by 183W NMR spectroscopy.
The calculation of the heat release rate by oxygen consumption in a controlled‐atmosphere cone calorimeter
Authors: Werrel Martin , Deubel Jan H. , Krüger Simone , Hofmann Anja , Krause Ulrich 
Published: January 2013

ABSTRACTThe standard cone calorimeter according to ASTM E 1354 and ISO 5660 enables reaction‐to‐fire tests to be performed in ambient atmospheric conditions. A controlled‐atmosphere chamber modifies the standard apparatus in a way that allows tests to be performed in nonambient conditions as well. The enclosed chamber is placed underneath the standard exhaust hood and does not have a closed connection to the hood. With this open arrangement, the exhaust gases are diluted by excess air drawn in from the laboratory surroundings. Heat‐induced changes in the consequential dilution ratio affect the calculation of fire quantities and, when neglected, lead to deviations of up to 30% in heat release rate. The paper introduces a test protocol and equations to calculate the heat release rate taking dilution effects into account. A mathematical correction is shown that compensates for the dilution effects while avoiding extensive mechanical changes in the equipment. Copyright © 2013 John Wiley & Sons, Ltd.
CO2 capture by antisublimation process and its technical economic analysis
Authors: Pan Xueqin , Clodic Denis , Toubassy Joseph 
Published: January 2013

AbstractCO2 capture by antisublimation consists in cooling the flue gases down to the freezing temperature of CO2 and frosting CO2 on a low temperature heat exchanger surface at a temperature range defined by the CO2 concentration in the flue gases and the CO2 capture efficiency. CO2 is then defrosted and recovered in a liquid state. This CO2 capture process by antisublimation is called AnSU®. The CO2 frosting temperature in flue gases is much lower than the triple point of water and therefore before CO2 capture, water contained in flue gases is removed to reach high purity CO2.This paper presents an overview of the antisublimation process and a brief review of test benches that have been set up in laboratory and on industry sites for validation and optimization of the antisublimation process dating back to the first one constructed in 2003. Energy consumption and cost penalty of CO2 capture by antisublimation are evaluated for a coal‐fired power plant. A technical and economic analysis has been made and compared to CO2 capture by oxycombustion for a cement plant. Those two processes can be seen as cryogenics options and the detailed comparison gives insight into where energy losses take place and which capture process could be most adapted depending on specifications of the cement industry. © 2012 Society of Chemical Industry and John Wiley & Sons, Ltd
Spatio‐temporal sedimentation patterns in beaver ponds along the Chevral river, Ardennes, Belgium
Authors: de Visscher M. , Nyssen J. , Pontzeele J. , Billi P. , Frankl A. 
Published: January 2013

AbstractWith the recovery of the European beaver (Castor fiber) and their capacity to engineer fluvial landscapes, questions arise as to how they influence sediment transport, including the spatio‐temporal trends and patterns of sedimentation in beaver ponds. The Chevral river (Ardennes, Belgium) contains two beaver dam sequences, which appeared in 2004. Volumes of sediment deposited behind the dams were measured, and grain‐size distribution patterns were determined. Flow discharges and sediment fluxes were measured at the inflow and outflow of each dam sequence. Between 2004 and 2011, 1710.1 m3 of sediment was deposited behind the beaver dams, with an average sediment thickness of 25.1 cm. The thickness of the sediment layer was significantly (p < 0.001) related to the area of the beaver ponds. Along the stream, beaver pond sediment thickness displayed a sinusoidal deposition pattern, in which ponds with thick sediment layers were preceded by a series of ponds with thinner sediment layers. A downstream textural coarsening in the dam sequences was also observed, probably because of dam failures subsequent to surges. Differences in sediment flux between the inflow and outflow at the beaver pond sequence were related to the river hydrograph, with deposition taking place during the rising limbs and slight erosion during the falling limbs. The 7‐year‐old sequences have filtered 190.19 ton of sediment out of the Chevral river, which is of the same order of magnitude as the 374.4 ton measured in pond deposits, with the difference between the values corresponding to beaver excavations (60.24 ton), inflow from small tributaries, and runoff from the valley flanks. Hydrogeomorphic effects of C. fiber and Castor canadensis activity are similar in magnitude. The detailed analysis of sedimentation in beaver pond sequences confirms the potential of beavers to contribute to river and wetland restoration, and catchment management. Copyright © 2013 John Wiley & Sons, Ltd.
Physiological functions of protein kinase D in vivo
Authors: Ellwanger Kornelia , Hausser Angelika 
Published: January 2013

AbstractThe cellular functions of the serine/threonine protein kinase D (PKD) have been extensively studied within the last decade and distinct roles such as fission of vesicles at the Golgi compartment, coordination of cell migration and invasion, and regulation of gene transcription have been correlated with this kinase family. Here, we highlight the current state of in vivo studies on PKD function with a focus on animal models and discuss the molecular basis of the observed phenotypic characteristics associated with this kinase family. © 2013 IUBMB Life, 65(2)98–107, 2013
Synthesize, Characterization and Application of Phosphine‐free Polymer Supported Palladium Nanoparticles as Effective Catalyst in Suzuki‐Miyaura Cross‐coupling Reactions
Authors: Mahdavi Hossein , Hashemi Payam 
Published: January 2013

AbstractHeterogeneous catalysts were developed by supporting palladium nanoparticles on modified cross‐linked polyacrylamide and successfully applied in Suzuki‐Miyaura cross‐coupling reactions. These catalysts are stable to air and moisture, and no sign of metal leaching was detected during the reactions as judged by elemental analysis of palladium by ICP‐OES technique and hot filtration test, which demonstrates the heterogeneous character of the catalysts. High yields of desired products were resulted by using these phosphine‐free catalysts at temperatures below 80 °C without aid of any additional ligands. The heat stability of the catalysts at the operating temperature was confirmed by thermogravimetric analysis (TGA). These catalysts are easy to use and cost effective. They can be recovered from reaction mixture by a simple filtration and reused in more successive reactions without significant loss in activity. The catalyst activity was restored by an ultrasonication program after deactivation in 10 cycles.
Fabrication of 105Y, Alpha 1‐Anti Trypsin Peptide Conjugated Hybrid Nanoparticles for Biological Applications
Authors: Viswanathan Kaliyaperumal , Hong De gang , Chu Wu‐Ching , Lee Y. C. 
Published: January 2013

AbstractIn this report, we describe the characterizations and applications of hybrid nanoparticles. These nanoparticles have been synthesized by combination of organometallic, polymerization process and functionalized with a specific peptide for targeting expressed serpin‐enzyme complex (SEC) receptor of human hepatoma HepG2 cells. By using peptide conjugated hybrid nanoparticles, the specific receptor targeting, collections of cells were successfully achieved. The cell collection results indicated that, the maximum up to 95.32% of HepG2 cell were collected. The 5‐dimethylthiazol‐2‐yl‐2,5‐diphenyltetrazolium bromide (MTT) assay of HepG2 cells incubated with these nanoparticles indicated that, the peptide conjugated hybrid nanoparticles did not possess significant cytotoxicity. The rotating magnetic field induced cell death studies indicated that, the HepG2 cell showed up to 70% of cell death was induced by hybrid nanoparticles under magnetic field. Concluding, these studies demonstrate that the hybrid nanoparticles have the capability of effective separation, imaging, targeting and killing of the human hepatoma cells.