bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reversible amorphization and the catalytically active state of crystalline Co3O4 during oxygen evolution
Authors: Bergmann Arno , Martinez-Moreno Elias , Teschner Detre , Chernev Petko , Gliech Manuel , de Araújo Jorge Ferreira , Reier Tobias , Dau Holger , Strasser Peter 
Published: October 2015

AbstractWater splitting catalysed by earth-abundant materials is pivotal for global-scale production of non-fossil fuels, yet our understanding of the active catalyst structure and reactivity is still insufficient. Here we report on the structurally reversible evolution of crystalline Co3O4 electrocatalysts during oxygen evolution reaction identified using advanced in situ X-ray techniques. At electrode potentials facilitating oxygen evolution, a sub-nanometre shell of the Co3O4 is transformed into an X-ray amorphous CoOx(OH)y which comprises di-μ-oxo-bridged Co3+/4+ ions. Unlike irreversible amorphizations, here, the formation of the catalytically-active layer is reversed by re-crystallization upon return to non-catalytic electrode conditions. The Co3O4 material thus combines the stability advantages of a controlled, stable crystalline material with high catalytic activity, thanks to the structural flexibility of its active amorphous oxides. We propose that crystalline oxides may be tailored for generating reactive amorphous surface layers at catalytic potentials, just to return to their stable crystalline state under rest conditions.
Cobalt-centred boron molecular drums with the highest coordination number in the CoB16− cluster
Authors: Popov Ivan A. , Jian Tian , Lopez Gary V. , Boldyrev Alexander I. , Wang Lai-Sheng 
Published: October 2015

AbstractThe electron deficiency and strong bonding capacity of boron have led to a vast variety of molecular structures in chemistry and materials science. Here we report the observation of highly symmetric cobalt-centered boron drum-like structures of CoB16−, characterized by photoelectron spectroscopy and ab initio calculations. The photoelectron spectra display a relatively simple spectral pattern, suggesting a high symmetry structure. Two nearly degenerate isomers with D8d (I) and C4v (II) symmetries are found computationally to compete for the global minimum. These drum-like structures consist of two B8 rings sandwiching a cobalt atom, which has the highest coordination number known heretofore in chemistry. We show that doping of boron clusters with a transition metal atom induces an earlier two-dimensional to three-dimensional structural transition. The CoB16− cluster is tested as a building block in a triple-decker sandwich, suggesting a promising route for its realization in the solid state.
Adiposity and immune-muscle crosstalk in South Asians & Europeans: A cross-sectional study
Authors: Samaan M.Constantine , Anand Sonia S. , Sharma Arya M. , Bonner Ashley , Beyene Joseph , Samjoo Imtiaz , Tarnopolsky Mark A. 
Published: October 2015

AbstractSouth Asians (SA) are at higher risk of cardiometabolic disorders than Europeans (EU), yet the potential determinants of this risk are poorly understood. We tested the hypotheses that 1) South Asians (SA) have greater muscle inflammation compared to Europeans (EU) at similar fat mass 2) differential regional adiposity in SA compared to EU is associated with enhanced muscle inflammation in SA. This cross-sectional study was conducted at a tertiary academic center in Hamilton, Ontario, Canada. The study included 29 EU and 26 SA. Quantitative real-time PCR and western blot were used to measure muscle inflammation. Statistical analysis was done using a General Linear Model. Despite having similar macrophage content to EU, SA muscle had lower levels of chemokine CCL2 compared to EU at gene expression (β -1.099, SE β 0.521, p-value 0.04) and protein (0.84 ± 0.69 versus 1.10 ± 0.60, p-value 0.052) levels. SA had more pronounced abdominal and hepatic adiposity, with smaller Intramyocellular lipid particles compared to EU (0.26 ± 0.12 μm2 versus 0.15 ± 0.06 μm2, p-value 0.02). In conclusion, CCL2 downregulation in SA may be an attempt to protect muscle against macrophage infiltration and defects in fatty acid partitioning to muscle may lead to the disproportionate adiposity and adverse cardiometabolic profile in SA.
Audiovisual temporal recalibration occurs independently at two different time scales
Authors: Van der Burg Erik , Alais David , Cass John 
Published: October 2015

AbstractCombining signals across the senses improves precision and speed of perception, although this multisensory benefit declines for asynchronous signals. Multisensory events may produce synchronized stimuli at source but asynchronies inevitably arise due to distance, intensity, attention and neural latencies. Temporal recalibration is an adaptive phenomenon that serves to perceptually realign physically asynchronous signals. Recently, it was discovered that temporal recalibration occurs far more rapidly than previously thought and does not require minutes of adaptation. Using a classical audiovisual simultaneity task and a series of brief flashes and tones varying in onset asynchrony, perceived simultaneity on a given trial was found to shift in the direction of the preceding trial’s asynchrony. Here we examine whether this inter-trial recalibration reflects the same process as prolonged adaptation by combining both paradigms: participants adapted to a fixed temporal lag for several minutes followed by a rapid series of test trials requiring a synchrony judgment. Interestingly, we find evidence of recalibration from prolonged adaptation and inter-trial recalibration within a single experiment. We show a dissociation in which sustained adaptation produces a large but decaying recalibration effect whilst inter-trial recalibration produces large transient effects whose sign matches that of the previous trial.
A Stable Dual-wavelength Thulium-doped Fiber Laser at 1.9 μm Using Photonic Crystal Fiber
Authors: Soltanian M. R. K. , Ahmad H. , Khodaie A. , Amiri I. S. , Ismail M. F. , Harun S. W. 
Published: October 2015

AbstractA stable dual-wavelength thulium-doped fiber laser operating at 1.9 μm using a short length of photonic crystal fiber (PCF) has been proposed and demonstrated. The photonics crystal fiber was 10 cm in length and effectively acted as a Mach-Zehnder interferometry element with a free spectral range of 0.2 nm. This dual-wavelength thulium-doped fiber laser operated steadily at room temperature with a 45 dB optical signal-to-noise-ratio.
A calmodulin like EF hand protein positively regulates oxalate decarboxylase expression by interacting with E-box elements of the promoter
Authors: Kamthan Ayushi , Kamthan Mohan , Kumar Avinash , Sharma Pratima , Ansari Sekhu , Thakur Sarjeet Singh , Chaudhuri Abira , Datta Asis 
Published: October 2015

AbstractOxalate decarboxylase (OXDC) enzyme has immense biotechnological applications due to its ability to decompose anti-nutrient oxalic acid. Flammulina velutipes, an edible wood rotting fungus responds to oxalic acid by induction of OXDC to maintain steady levels of pH and oxalate anions outside the fungal hyphae. Here, we report that upon oxalic acid induction, a calmodulin (CaM) like protein-FvCaMLP, interacts with the OXDC promoter to regulate its expression. Electrophoretic mobility shift assay showed that FvCamlp specifically binds to two non-canonical E-box elements (AACGTG) in the OXDC promoter. Moreover, substitutions of amino acids in the EF hand motifs resulted in loss of DNA binding ability of FvCamlp. F. velutipes mycelia treated with synthetic siRNAs designed against FvCaMLP showed significant reduction in FvCaMLP as well as OXDC transcript pointing towards positive nature of the regulation. FvCaMLP is different from other known EF hand proteins. It shows sequence similarity to both CaMs and myosin regulatory light chain (Cdc4), but has properties typical of a calmodulin, like binding of 45Ca2+, heat stability and Ca2+ dependent electrophoretic shift. Hence, FvCaMLP can be considered a new addition to the category of unconventional Ca2+ binding transcriptional regulators.
Designed synthesis of double-stage two-dimensional covalent organic frameworks
Authors: Chen Xiong , Addicoat Matthew , Jin Enquan , Xu Hong , Hayashi Taku , Xu Fei , Huang Ning , Irle Stephan , Jiang Donglin 
Published: October 2015

AbstractCovalent organic frameworks (COFs) are an emerging class of crystalline porous polymers in which organic building blocks are covalently and topologically linked to form extended crystalline polygon structures, constituting a new platform for designing π-electronic porous materials. However, COFs are currently synthesised by a few chemical reactions, limiting the access to and exploration of new structures and properties. The development of new reaction systems that avoid such limitations to expand structural diversity is highly desired. Here we report that COFs can be synthesised via a double-stage connection that polymerises various different building blocks into crystalline polygon architectures, leading to the development of a new type of COFs with enhanced structural complexity and diversity. We show that the double-stage approach not only controls the sequence of building blocks but also allows fine engineering of pore size and shape. This strategy is widely applicable to different polymerisation systems to yield hexagonal, tetragonal and rhombus COFs with predesigned pores and π-arrays.
Ring finger protein 166 potentiates RNA virus-induced interferon-β production via enhancing the ubiquitination of TRAF3 and TRAF6
Authors: Chen Hai-Wei , Yang Yong-Kang , Xu Hao , Yang Wei-Wei , Zhai Zhong-He , Chen Dan-Ying 
Published: October 2015

AbstractHost cells orchestrate the production of IFN-β upon detecting invading viral pathogens. Here, we report that Ring finger protein 166 (RNF166) potentiates RNA virus-triggered IFN-β production. Overexpression of RNF166 rather than its homologous proteins RNF114, RNF125 and RNF138, enhanced Sendai virus (SeV)-induced activation of the IFN-β promoter. Knockdown of endogenous RNF166, but not other RNFs, inhibited the IFN-β production induced by SeV and encephalomyocarditis virus. RNF166 interacted with TRAF3 and TRAF6. SeV-induced ubiquitination of TRAF3 and TRAF6 was suppressed when endogenous RNF166 rather than RNF114/138 was knocked down. These findings suggest that RNF166 positively regulates RNA virus-triggered IFN-β production by enhancing the ubiquitination of TRAF3 and TRAF6.
Structure, dynamics and stability of water/scCO2/mineral interfaces from ab initio molecular dynamics simulations
Authors: Lee Mal-Soon , Peter McGrail B. , Rousseau Roger , Glezakou Vassiliki-Alexandra 
Published: October 2015

AbstractThe boundary layer at solid-liquid interfaces is a unique reaction environment that poses significant scientific challenges to characterize and understand by experimentation alone. Using ab initio molecular dynamics (AIMD) methods, we report on the structure and dynamics of boundary layer formation, cation mobilization and carbonation under geologic carbon sequestration scenarios (T = 323 K and P = 90 bar) on a prototypical anorthite (001) surface. At low coverage, water film formation is enthalpically favored, but entropically hindered. Simulated adsorption isotherms show that a water monolayer will form even at the low water concentrations of water-saturated scCO2. Carbonation reactions readily occur at electron-rich terminal Oxygen sites adjacent to cation vacancies that readily form in the presence of a water monolayer. These results point to a carbonation mechanism that does not require prior carbonic acid formation in the bulk liquid. This work also highlights the modern capabilities of theoretical methods to address structure and reactivity at interfaces of high chemical complexity.
Super-radiant mode in InAs—monolayer–based Bragg structures
Authors: Pozina G. , Kaliteevski M. A. , Nikitina E. V. , Denisov D. V. , Polyakov N. K. , Pirogov E. V. , Goray L. I. , Gubaydullin A. R. , Ivanov K. A. , Kaliteevskaya N. A. , Egorov A. Yu. , Clark S. J. 
Published: October 2015

AbstractWe report direct experimental evidence of the collective super-radiant mode in Bragg structure containing 60 InAs monolayer-based quantum wells (QWs) periodically arranged in GaAs matrix. Time-resolved photoluminescence measurements reveal an appearance of the additional super-radiant mode, originated from coherent collective interaction of QWs. This mode demonstrates a super-linear dependence of the intensity and radiative decay rate on the excitation power. The super-radiant mode is not manifested in the case if only a small number of QWs is excited.
Modification of the association between maternal smoke exposure and congenital heart defects by polymorphisms in glutathione S-transferase genes
Authors: Li Xiaohong , Liu Zhen , Deng Ying , Li Shengli , Mu Dezhi , Tian Xiaoxian , Lin Yuan , Yang Jiaxiang , Li Jun , Li Nana , Wang Yanping , Chen Xinlin , Deng Kui , Zhu Jun 
Published: October 2015

AbstractCongenital heart defects (CHDs) arise through various combinations of genetic and environmental factors. Our study explores how polymorphisms in the glutathione S-transferase (GST) genes affect the association between cigarette smoke exposure and CHDs. We analysed 299 mothers of children with CHDs and 284 mothers of children without any abnormalities who were recruited from six hospitals. The hair nicotine concentration (HNC) was used to quantify maternal smoke exposure and the maternal GSTT1 and GSTM1 and GSTP1 genes were sequenced. We found a trend of higher adjusted odds ratios with higher maternal HNC levels, suggesting a dose-response relationship between maternal smoke exposure and CHDs. The lowest HNC range associated with an increased risk of CHDs was 0.213–0.319 ng/mg among the mothers with functional deletions of GSTM1 or GSTT1and 0.319–0.573 ng/mg among the mothers with normal copies of GSTM1 and GSTT1. In addition, the adjusted odds ratio for an HNC of >0.573 ng/mg was 38.53 among the mothers with the GSTP1 AG or GG genotype, which was 7.76 (χ2 = 6.702, p = 0.010) times greater than the AOR in the mothers with GSTP1 AA genotype. Our study suggests that polymorphisms of maternal GST genes may modify the association of maternal smoke exposure with CHDs.
Migraine and possible etiologic heterogeneity for hormone-receptor-negative breast cancer
Authors: Shi Min , DeRoo Lisa A. , Sandler Dale P. , Weinberg Clarice R. 
Published: October 2015

AbstractMigraine headache is often timed with the menstrual cycle. Some studies have reported reduced risk of breast cancer in migraineurs but most of those did not distinguish menstrually-related from non-menstrually-related migraine. To examine the possible associations between breast cancer and migraine overall and between cancer subcategories and the two migraine subtypes, we used a cohort study of 50,884 women whose sister had breast cancer and a sister-matched case-control study including 1,418 young-onset (<50 years) breast cancer cases. We analyzed the two studies individually and also in tandem via a hybrid Cox model, examining subcategories of breast cancer in relation to menstrually-related and non-menstrually-related migraine. History of migraine was not associated with breast cancer overall. Migraine showed an inverse association with ductal carcinoma in situ (HR = 0.77; 95% CI (0.62,0.96)). Also, women with non-menstrually-related migraine had increased risk (HR = 1.30, 95% CI (0.93,1.81)) while women with menstrually-related migraine had decreased risk (HR = 0.63, 95% CI (0.42,0.96)) of hormone-receptor-negative (ER−/PR−) cancer, with a significant contrast in estimated effects (P = 0.005). While replication of these subset-based findings will be needed, effect specificity could suggest that while migraine has little overall association with breast cancer, menstrual migraine may be associated with reduced risk of ER−/PR− breast cancer.
Lithium Sulfur Primary Battery with Super High Energy Density: Based on the Cauliflower-like Structured C/S Cathode
Authors: Ma Yiwen , Zhang Hongzhang , Wu Baoshan , Wang Meiri , Li Xianfeng , Zhang Huamin 
Published: October 2015

AbstractThe lithium-sulfur primary batteries, as seldom reported in the previous literatures, were developed in this work. In order to maximize its practical energy density, a novel cauliflower-like hierarchical porous C/S cathode was designed, for facilitating the lithium-ions transport and sulfur accommodation. This kind of cathode could release about 1300 mAh g−1 (S) capacity at sulfur loading of 6 ~ 14 mg cm−2 and showed excellent shelf stability during a month test at room temperature. As a result, the assembled Li-S soft package battery achieved an energy density of 504 Wh kg−1 (654 Wh L−1), which was the highest value ever reported to the best of our knowledge. This work might arouse the interests on developing primary Li-S batteries, with great potential for practical application.
The physical mechanism of magnetic field controlled magnetocaloric effect and magnetoresistance in bulk PrGa compound
Authors: Zheng X. Q. , Wu H. , Chen J. , Zhang B. , Li Y. Q. , Hu F. X. , Sun J. R. , Huang Q. Z. , Shen B. G. 
Published: October 2015

AbstractThe PrGa compound shows excellent performance on the magnetocaloric effect (MCE) and magnetoresistance (MR). The physical mechanism of MCE and MR in PrGa compound was investigated and elaborated in detail on the basis of magnetic measurement, heat capacity measurement and neutron powder diffraction (NPD) experiment. New types of magnetic structure and magnetic transition are found. The results of the NPD along with the saturation magnetic moment (MS) and magnetic entropy (SM) indicate that the magnetic moments are randomly distributed within the equivalent conical surface in the ferromagnetic (FM) temperature range. PrGa compound undergoes an FM to FM transition and an FM to paramagnetic (PM) transition as temperature increases. The magnetizing process was discussed in detail and the physical mechanism of the magnetic field controlled magnetocaloric effect (MCE) and the magnetoresistance (MR) was studied. The formation of the plateau on MCE curve was explained and MR was calculated in detail on the basis of the magnetic structure and the analysis of the magnetizing process. The experimental results are in excellent agreement with the calculations. Finally, the expression of MR = β(T)X2 and its application conditions were discussed, where X is M(H)/Meff and Meff is the paramagnetic effective moment.
Fast optical cooling of a nanomechanical cantilever by a dynamical Stark-shift gate
Authors: Yan Leilei , Zhang Jian-Qi , Zhang Shuo , Feng Mang 
Published: October 2015

AbstractThe efficient cooling of nanomechanical resonators is essential to exploration of quantum properties of the macroscopic or mesoscopic systems. We propose such a laser-cooling scheme for a nanomechanical cantilever, which works even for the low-frequency mechanical mode and under weak cooling lasers. The cantilever is coupled by a diamond nitrogen-vacancy center under a strong magnetic field gradient and the cooling is assisted by a dynamical Stark-shift gate. Our scheme can effectively enhance the desired cooling efficiency by avoiding the off-resonant and undesired carrier transitions and thereby cool the cantilever down to the vicinity of the vibrational ground state in a fast fashion.
The basic helix-loop-helix transcription factor, Mist1, induces maturation of mouse fetal hepatoblasts
Authors: Chikada Hiromi , Ito Keiichi , Yanagida Ayaka , Nakauchi Hiromitsu , Kamiya Akihide 
Published: October 2015

AbstractHepatic stem/progenitor cells, hepatoblasts, have a high proliferative ability and can differentiate into mature hepatocytes and cholangiocytes. Therefore, these cells are considered to be useful for regenerative medicine and drug screening for liver diseases. However, it is problem that in vitro maturation of hepatoblasts is insufficient in the present culture system. In this study, a novel regulator to induce hepatic differentiation was identified and the molecular function of this factor was examined in embryonic day 13 hepatoblast culture with maturation factor, oncostatin M and extracellular matrices. Overexpression of the basic helix-loop-helix type transcription factor, Mist1, induced expression of mature hepatocytic markers such as carbamoyl-phosphate synthetase1 and several cytochrome P450 (CYP) genes in this culture system. In contrast, Mist1 suppressed expression of cholangiocytic markers such as Sox9, Sox17, Ck19 and Grhl2. CYP3A metabolic activity was significantly induced by Mist1 in this hepatoblast culture. In addition, Mist1 induced liver-enriched transcription factors, CCAAT/enhancer-binding protein α and Hepatocyte nuclear factor 1α, which are known to be involved in liver functions. These results suggest that Mist1 partially induces mature hepatocytic expression and function accompanied by the down-regulation of cholangiocytic markers.
Mismatch negativity in common marmosets: Whole-cortical recordings with multi-channel electrocorticograms
Authors: Komatsu Misako , Takaura Kana , Fujii Naotaka 
Published: October 2015

AbstractMismatch negativity (MMN) is a component of event-related potentials (ERPs) evoked by violations of regularity in sensory stimulus-series in humans. Recently, the MMN has received attention as a clinical and translatable biomarker of psychiatric disorders such as schizophrenia and for the development animal models of these psychiatric disorders. In this study, we investigated the generation of MMN in common marmosets, which are an important non-human primate model with genetic manipulability. We recorded the electrocorticograms (ECoGs) from two common marmosets with epidurally implanted electrodes covering a wide range of cortical regions. ECoG recordings were conducted in a passive listening condition with a roving oddball paradigm. We compared the ERPs evoked by repeatedly presented standard stimuli and those evoked by the deviant stimuli. Significant differences in the ERPs were observed in several cortical areas. In particular, deviant stimuli elicited larger negative activity than standard stimuli in the temporal area. In addition, the latency and polarity of the activity were comparable to human MMNs. This is thus the first report of MMN-like activity in common marmosets. Our findings have the potential to advance future gene-manipulation studies that aim to establish non-human primate models of schizophrenia.