bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessment of sexual dysfunction and determination of its risk factors in the Republic of Korea
Authors: Choi Hoon , Kim Jae‐Heon , Park Jae‐Young , Shim Ji‐Sung , Lee Jeong‐Gu , Yoon Hae‐Young , Bae Jae‐Hyun 
Published: January 2014

AbstractObjectiveTo assess sexual function among women via self‐evaluation of female sexual dysfunction (FSD) and to determine risk factors for FSD among Korean women.MethodsA preliminary questionnaire‐based study in Ansan, Korea, enrolled 935 women between January and December 2010. Participants completed the Female Sexual Function Index and a self‐administered survey. Participants were divided into 2 groups: in the recognized group (RG), women were aware of their sexual problems; in the unrecognized group (URG), women were not.ResultsThe prevalence of FSD was 46.1% (n = 431). The prevalence of recognized FSD was 21.5% (n = 201), whereas that of unrecognized FSD was 24.6% (n = 230) Younger women showed a significantly more positive attitude toward sex compared with older individuals (P < 0.001). Sexual desire, sexual arousal, dyspareunia, lubrication, and sexual satisfaction were factors of sexual dysfunction in the RG. In the URG, sexual arousal, sexual desire, orgasm, dyspareunia, and sexual satisfaction were identified as significant factors.ConclusionWomen in the RG had positive attitudes toward sex, whereas those in the URG had negative attitudes. Women who were unsatisfied with their sexual life did not express a need for treatment. The sociocultural background of Korean women should be considered in the diagnosis and treatment of FSD.
The benefits of retail therapy: Making purchase decisions reduces residual sadness
Authors: Rick Scott I. , Pereira Beatriz , Burson Katherine A. 
Published: January 2014

AbstractPeople often shop when feeling sad, but whether and why shopping reduces residual (lingering) sadness remains an open question. Sadness is strongly associated with a sense that situational forces control the outcomes in one's life, and thus we theorized that the choices inherent in shopping may restore personal control over one's environment and reduce residual sadness. Three experiments provided support for our hypothesis. Making shopping choices helped to alleviate sadness whether they were hypothetical (Experiment 1) or real (Experiment 2). In addition, all experiments found support for the underlying mechanism of personal control restoration. Notably, the benefits of restored personal control over one's environment do not generalize to anger (Experiments 2 and 3), because anger is associated with a sense that other people (rather than situational forces) are likely to cause negative outcomes, and these appraisals are not ameliorated by restoring personal control over one's environment.
A case of typical atrioventricular nodal (AVN) reentrant tachycardia confined to the compact AV node, showing a variety of rare electrophysiological findings, including eccentric AVN echoes
Authors: Tanaka Kazushi , Shiotani Shinji , Fukuda Keisuke , Fujihara Masahiko , Higashimori Akihiro , Morioka Nobuyuki , Yokoi Yoshiaki , Fujimura Osamu 
Published: January 2014

AbstractHerein, we report the case of a 49‐year‐old woman with typical atrioventricular nodal (AVN) reentrant tachycardia, confined to the compact atrioventricular node, showing numerous rare electrophysiological findings such as unique AVN reentrant echoes, double ventricular responses, latent retrograde dual AVN pathways, antegrade triple AVN pathways, and longitudinal dissociation within the lower final common pathway.
Akkreditierung von Weiterbildungsgängen für Psychologieberufe in der Schweiz – ein neues Gesetz setzt neue Qualitätsanforderungen
Authors: Gasser Floriane 
Published: January 2014

Einleitung
Das OAQ ist die Agentur für Akkreditierung und Qualitätssicherung der schweizerischen Hochschulen. Es unterstützt das Bundesamt für Gesundheit (BAG) bei der Akkreditierung der Weiterbildungsgänge in den Psychologieberufen. Mit dem Psychologieberufegesetz (PsyG), das am 1. April 2013 in Kraft getreten ist, werden die Weiterbildung sowie die Berufsausübung in diesem Fachbereich erstmals umfassend reglementiert. Bis 2018 müssen ca. 60 Weiterbildungsgänge akkreditiert werden. Um diese umfangreiche Aufgabe effektiv und termingerecht umsetzen zu können, kooperiert das OAQ mit der deutschen Akkreditierungsagentur im Bereich Gesundheit und Soziales (AHPGS).
Arzneimittelversorgung bei psychischen Erkrankungen
Authors: Glaeske Gerd 
Published: January 2014

Einleitung
Die Arzneimittelversorgung mit Psychopharmaka hat sich in den vergangenen Jahren erheblich verändert. Der größte Anteil entfiel noch 1992 auf Tranquilizer vom Benzodiazepin-Typ, im Jahre 2012 sind die Antidepressiva zur meist verordneten Gruppe der Psychopharmaka geworden, vor allem wegen des starken Verordnungsanstiegs von Serotoninwiederaufnahmehemmern (SSRI). Die Evidenz für die Behandlung milder Depressionen gegenüber Placebo ist fraglich, bei der Behandlung von bipolaren Störungen werden vor allem SSRI und Lithium eingesetzt.
Kritische Lebensereignisse
Authors: Ladwig Karl-Heinz 
Published: January 2014

Einleitung
Ein kritisches Lebensereignis ist ein,,distinktes Geschehnis“, das mit hoher Wahrscheinlichkeit im Lebens eines jeden Menschen auftreten kann, dabei eine qualitativ-strukturelle Anpassungsleistung erfordert und eine nachhaltige emotionale Reaktion auslösen kann. Die Anpassungsstörungen sind (Fehl-) Reaktionen auf multiple kritische Lebensereignisse, die bei mangelnder Bewältigungsfähigkeit zu einer Belastung werden. Dagegen ist ein Trauma ein Ereignis von außergewöhnlicher Bedrohung oder katastrophalem Ausmaß, welches ein notwendiges, aber nicht hinreichendes Kriterium für das Auftreten einer posttrauamatschen Belastungsstörung ist.
Sozioökonomischer Status und psychische Gesundheit
Authors: Lampert Thomas , Kroll Lars Eric , Hapke Ulfert , Jacobi Frank 
Published: January 2014

Einleitung
Eine Vielzahl an Studien weist den sozioökonomischen Status als einflussreiche Determinante der Gesundheit und Lebenserwartung aus. Der Beitrag beschreibt, welche Erkenntnisse zum Zusammenhang zwischen dem sozioökonomischen Status und der psychischen Gesundheit für die Allgemeinbevölkerung in Deutschland vorliegen. Außerdem wird dargestellt, welche weiterführenden Forschungsperspektiven mit der,,Studie zur Gesundheit Erwachsener in Deutschland“ (DEGS1) und dem angeschlossenen Modul zur psychischen Gesundheit verbunden sind.
Die Messung von Burnout-Symptomen und Risikofaktoren mit COPSOQ
Authors: Lincke Hans-Joachim , Nübling Matthias 
Published: January 2014

Einleitung
Die Messung von Burnout-Symptomen mit COPSOQ ist ein wichtiger Beitrag zur Beurteilung psychischer Gefährdung bei der Arbeit. Der Vergleich der Ausprägungen eines Betriebs mit der COPSOQ-Datenbank zeigt das Gefährdungsmaß. Für Präventionsmaßnahmen werden negative und positive Einflussfaktoren identifiziert. Die empirische Modellierung von Zusammenhängen zwischen Burnout-Symptomen und -Ursachen bietet dem BGM Ansatzpunkte zum Schutz und zur Förderung der Gesundheit von Beschäftigten.
PEPP: Statt sektorübergreifender Versorgung ein insuffizientes Abrechnungssystem
Authors: Munk Ingrid 
Published: January 2014

Einleitung
Der Artikel bewertet kritisch die Folgen der Einführung des neuen Entgeltgesetzes in der Psychiatrie, das auf einem DRG-ähnlichen System mit pauschalisierten Entgelten (= PEPP) basiert. Im Fokus sind insbesondere die Anreizwirkungen zur Erbringung stationärer Leistungen. Damit kontrastiert werden die Erfordernisse eines modernen psychiatrischen Versorgungssystem mit sektorübergreifender Versorgung unter Einschluss von Home Treatment (= Akutbehandlung zu Hause).
Rehabilitation psychisch Kranker
Authors: Winter Thomas 
Published: January 2014

Einleitung
Psychische Erkrankungen betreffen häufig Adoleszente und junge Erwachsene. Damit verbunden sind mitunter erhebliche Konsequenzen für die die soziale Integration. Die Rehabilitation psychisch Kranker ist dabei ein kontinuierlicher Prozeß, der ausreichend Zeit im passenden Umfeld unter qualifizierter Betreuung mit störungsspezifischen Behandlungsangeboten erfordert. Kürzere Verweildauern in der Akutpsychiatrie mit nicht immer abgeschlossener Stabilisierung der Patienten beeinflussen den Zugang zur Rehabilitation, der für chronisch Kranke besonders erschwert ist, da die Rehabilitationsindikation einen aktuellen Anlaß, typischerweise ein vorausgehendes akutes Erkrankungsereignis mit zu erwartender Besserung unterstellt. Zudem wäre ein Ausbau der Kapazitäten indikationsspezifischer Rehabilitationsangebote für psychisch Kranke sinnvoll.
Consumption ofBifidobacterium lactisBi-07 by healthy elderly adults enhances phagocytic activity of monocytes and granulocytes
Authors: Maneerat Sujira , Lehtinen Markus J. , Childs Caroline E. , Forssten Sofia D. , Alhoniemi Esa , Tiphaine Milin , Yaqoob Parveen , Ouwehand Arthur C. , Rastall Robert A. 
Published: January 2014

AbstractElderly adults have alterations in their gut microbiota and immune functions that are associated with higher susceptibility to infections and metabolic disorders. Probiotics and prebiotics, and their synbiotic combinations are food supplements that have been shown to improve both gut and immune function. The objective of this randomised, double-blind, placebo-controlled, cross-over human clinical trial was to study immune function and the gut microbiota in healthy elderly adults. Volunteers (n37) consumed prebiotic galacto-oligosaccharides (GOS; 8 g/d), probioticBifidobacterium lactisBi-07 (Bi-07; 109colony-forming units/d), their combination (Bi-07 + GOS) and maltodextrin control (8 g/d) in four 3-week periods separated by 4-week wash-out periods. Immune function was analysed by determining the phagocytic and oxidative burst activity of monocytes and granulocytes, whole-blood response to lipopolysaccharide, plasma chemokine concentrations and salivary IgA levels. Gut microbiota composition and faecal SCFA content were determined using 16S ribosomal RNA fluorescencein situhybridisation and HPLC, respectively. Primary statistical analyses indicated the presence of carry-over effects and thus measurements from only the first supplementation period were considered valid. Subsequent statistical analysis showed that consumption of Bi-07 improved the phagocytic activity of monocytes (P < 0·001) and granulocytes (P = 0·02). Other parameters were unchanged. We have for the first time shown that the probiotic Bi-07 may provide health benefits to elderly individuals by improving the phagocytic activity of monocytes and granulocytes. The present results also suggest that in the elderly, the effects of some probiotics and prebiotics may last longer than in adults.
Maternal high-fat diet alters expression of pathways of growth, blood supply and arachidonic acid in rat placenta
Authors: Dekker Nitert Marloes , Vaswani Kanchan , Hum Melissa , Chan Hsiu-Wen , Wood-Bradley Ryan , Henry Sarah , Armitage James A. , Mitchell Murray D. , Rice Gregory E. 
Published: January 2014

AbstractThe high fat content in Western diets probably affects placental function during pregnancy with potential consequences for the offspring in the short and long term. The aim of the present study was to compare genome-wide placental gene expression between rat dams fed a high-fat diet (HFD) and those fed a control diet for 3 weeks before conception and during gestation. Gene expression was measured by microarray and pathway analysis was performed. Gene expression differences were replicated by real-time PCR and protein expression was assessed by Western blot analysis. Placental and fetal weights at E17.25 were not altered by exposure to the maternal HFD. Gene pathways targeting placental growth, blood supply and chemokine signalling were up-regulated in the placentae of dams fed the HFD. The up-regulation in messenger RNA expression for five genes Ptgs2 (fatty acid cyclo-oxidase 2; COX2), Limk1 (LIM domain kinase 1), Pla2g2a (phospholipase A2), Itga1 (integrin α-1) and Serpine1 was confirmed by real-time PCR. Placental protein expression for COX2 and LIMK was also increased in HFD-fed dams. In conclusion, maternal HFD feeding alters placental gene expression patterns of placental growth and blood supply and specifically increases the expression of genes involved in arachidonic acid and PG metabolism. These changes indicate a placental response to the altered maternal metabolic environment.
Multi-scale community organization of the human structural connectome and its relationship with resting-state functional connectivity
Authors: BETZEL RICHARD F. , GRIFFA ALESSANDRA , AVENA-KOENIGSBERGER ANDREA , GOÑI JOAQUÍN , THIRAN JEAN-PHILIPPE , HAGMANN PATRIC , SPORNS OLAF 
Published: January 2014

AbstractThe human connectome has been widely studied over the past decade. A principal finding is that it can be decomposed into communities of densely interconnected brain regions. Past studies have often used single-scale modularity measures in order to infer the connectome's community structure, possibly overlooking interesting structure at other organizational scales. In this report, we used the partition stability framework, which defines communities in terms of a Markov process (random walk), to infer the connectome's multi-scale community structure. Comparing the community structure to observed resting-state functional connectivity revealed communities across a broad range of scales that were closely related to functional connectivity. This result suggests a mapping between communities in structural networks, models of influence-spreading and diffusion, and brain function. It further suggests that the spread of influence among brain regions may not be limited to a single characteristic scale.
THE CONCRESCENCE PROJECT (2008–2010): IDEAS, PROCESSES, EXPERIENCES, MUSICAL WORKS
Authors: Thoresen Lasse 
Published: January 2014

AbstractThis article discusses the concept, working practices and outcomes of the Concrescence Project, a research project initiated by the author oriented towards innovations in vocal practice and composition through experiments with combining vocal techniques from different cultures. The concept of ethnomodernism is explored, as are different attitudes to vocal sound production in a variety of musical traditions including the avant-garde, traditional styles from the Nordic/Baltic region, and overtone singing. The article concludes with a discussion of microtonal tunings, their notation, and their implementation in vocal composition.
FIRST IMPRESSIONS: ON THE PROGRAMMING AND CONCERT PRESENTATION OF NEW MUSIC TODAY
Authors: Gotham Mark 
Published: January 2014

AbstractThis article explores recent, radical developments in the ways in which new music is programmed and presented. It is contextualised by a brief survey of new music programming across the history of public concert-giving, and by several new interviews with industry professionals in the UK. These illustrate various rationales behind current practice including the dissatisfaction with traditional modes of concert-giving where appropriate. They also inform the author's conviction that different branches of new music benefit from different forms of presentation, acknowledging the importance of innovative forms to certain new styles.
Structural Characterization of the Cell Division Cycle inStrigomonas culicis, an Endosymbiont-Bearing Trypanosomatid
Authors: Brum Felipe Lopes , Catta-Preta Carolina Moura Costa , de Souza Wanderley , Schenkman Sergio , Elias Maria Carolina , Motta Maria Cristina Machado 
Published: January 2014

AbstractStrigomonas culicis(previously referred to asBlastocrithidia culicis) is a monoxenic trypanosomatid harboring a symbiotic bacterium, which maintains an obligatory relationship with the host protozoan. Investigations of the cell cycle in symbiont harboring trypanosomatids suggest that the bacterium divides in coordination with other host cell structures, particularly the nucleus. In this study we used light and electron microscopy followed by three-dimensional reconstruction to characterize the symbiont division during the cell cycle ofS. culicis. We observed that during this process, the symbiotic bacterium presents different forms and is found at different positions in relationship to the host cell structures. At the G1/S phase of the protozoan cell cycle, the endosymbiont exhibits a constricted form that appears to elongate, resulting in the bacterium division, which occurs before kinetoplast and nucleus segregation. During cytokinesis, the symbionts are positioned close to each nucleus to ensure that each daughter cell will inherit a single copy of the bacterium. These observations indicated that the association of the bacterium with the protozoan nucleus coordinates the cell cycle in both organisms.
Molecular and phenetic characterization of the bacterial assemblage of Hot Lake, WA, an environment with high concentrations of magnesium sulphate, and its relevance to Mars
Authors: Kilmer Brian R. , Eberl Timothy C. , Cunderla Brent , Chen Fei , Clark Benton C. , Schneegurt Mark A. 
Published: January 2014

AbstractHot Lake (Oroville, WA) is an athalassohaline epsomite lake that can have precipitating concentrations of MgSO4salts, mainly epsomite. Little biotic study has been done on epsomite lakes and it was unclear whether microbes isolated from epsomite lakes and their margins would fall within recognized halotolerant genera, common soil genera or novel phyla. Our initial study cultivated and characterized epsotolerant bacteria from the lake and its margins. Approximately 100 aerobic heterotrophic microbial isolates were obtained by repetitive streak-plating in high-salt media including either 10% NaCl or 2 M MgSO4. The collected isolates were all bacteria, nearly evenly divided between Gram-positive and Gram-negative clades, the most abundant genera beingHalomonas, Idiomarina, Marinobacter, Marinococcus, Nesterenkonia, NocardiopsisandPlanococcus. Bacillus, Corynebacterium, Exiguobacterium, KocuriaandStaphylococcusalso were cultured. This initial study included culture-independent community analysis of direct DNA extracts of lake margin soil using PCR-based clone libraries and 16S rRNA gene phylogeny. Clones assigned to Gram-positive bacterial clades (70% of total clones) were dominated by sequences related to uncultured actinobacteria. There were abundantDeltaproteobacteriaclones related to bacterial sulphur metabolisms and clones ofLegionellaandCoxiella. These epsomite lake microbial communities seem to be divided between bacteria primarily associated with hyperhaline environments rich in NaCl and salinotolerant relatives of common soil organisms. Archaea appear to be in low abundance and none were isolated, despite near-saturated salinities. Growth of microbes at very high concentrations of magnesium and other sulphates has relevance to planetary protection and life-detection missions to Mars, where scant liquid water may form as deliquescent brines and appear as eutectic liquids.
Contactin-1 regulates myelination and nodal/paranodal domain organization in the central nervous system
Authors: Çolakoğlu Gülsen , Bergstrom-Tyrberg Ulrika , Berglund Erik O. , Ranscht Barbara 
Published: January 2014

Significance
Myelin is a multilayered membrane sheath that encircles axons to enable rapid information processing and protect neurons. Formation of myelin requires communication between axons and oligodendrocytes, the myelin-forming cells in the CNS. Here we identify Contactin-1 as a critical signal for axon–glia communication in CNS myelin. Gene ablation in mice shows that Contactin-1 is necessary for myelin sheath formation by oligodendrocytes and establishment of paranodal axoglial junctions that regulate the domain organization and enable rapid nerve impulse conduction of myelinated nerves. The multiple and critical aspects of Contactin-1 in central myelin formation identified in the current study will guide novel approaches aimed at enhancing regeneration in demyelinating diseases that specifically affect the CNS.
Cisgenesis: a modern way of domesticating traits of the breeders' gene pool.
Authors: Jacobsen E. 
Published: January 2014

Abstract

Plant breeding is a multidisciplinary scientific activity with tool development as driving force. It is clear from history that availability of genetic variation and selection methods are bottom lines for variety development. The genetic source of traditional plant breeding is restricted to domestication of traits from the so-called 'breeders' gene pool', consisting of crossable sources. Gene cloning and genetic transformation broaden the available genetic variation to genes from all living organisms. The so-called new genes in genetically modified organism (GMO) plants, consist of transgenes, with (chimaeric) genes from outside the 'breeder's gene pool'. Transgenic plants needed additional biosafety rules such as Directive 2001/18EC. However, these are not needed after transformation of the four
rol
-genes from wild-type
Agrobacterium rhizogenes
. In the meantime, cloned cisgenes, natural dominant genes from 'breeders' gene pool', are available, enabling cisgenic crops after marker-free transformation, which extends plant breeding with traditional traits. From long-term experience, it is clear that traditional breeding with the 'breeders' gene pool' has a history of safe use. Different scientific committees concluded that cisgenic crops are as safe as traditionally bred varieties. So, cisgenesis is a powerful new tool for plant breeding with traditional traits as indicated in the potential examples on: (1) breeding for durable resistance to potato late blight and apple scab by
R
-gene stacking; (2) the new possibility to come to stacking of monogenic resistance alleles in wheat; (3) engineering of restoration of cytoplasmic male sterility by cloned restorer genes and of altering gametophytic incompatibility by introducing additional
S
-alleles; (4) increasing phytase activity by gene dosage effect in barley; and (5) the possibility of changing hormone metabolism in (fruit) trees leading to important morphological alterations. In near future, because of availability of many more cisgenes, it is expected that the possibilities of cisgenesis will increase rapidly as the next step in plant breeding with traditional traits, if treatment as non-GMO is approved.