bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical outcome of 42 dogs with scapular tumors treated by scapulectomy: A Veterinary Society of Surgical Oncology (VSSO) retrospective study (1995–2010)
Authors: Montinaro Vincenzo , Boston Sarah E. , Buracco Paolo , Culp William T.N. , Romanelli Giorgio , Straw Rod , Ryan Stewart 
Published: October 2013

AbstractObjectiveTo report signalment, clinical signs, preoperative staging tests, histologic diagnosis, surgical, and oncologic outcomes including postoperative limb use, in dogs with scapular tumors treated by scapulectomy.Study DesignRetrospective case seriesAnimalsDogs (n = 42) with scapular tumors.MethodsMedical records (1995–2010) from 6 hospitals were searched for dogs with scapular tumors treated by scapulectomy. Data retrieved were: signalment, weight, percentage of scapula removed, histologic diagnosis, postoperative limb use, adjunctive therapy, disease free interval (DFI), and survival time (ST). Individual variables were modeled with a Cox proportional hazard model accounting for censoring to determine risk factors for decreased DFI and ST. For categorical variables, Kaplan–Meier survival plots as well as mean and median survival times (MSTs) were calculated.ResultsSubtotal scapulectomy was performed in 18 dogs (42.9%). Osteosarcoma (OSA) was diagnosed in 27 dogs (64.3%). Limb use was evaluated immediately after surgery in 41 dogs. Information on limb use at other times (1, 2, 3, and >3 months) postoperatively was also available for some dogs and was good to excellent overall. Only adjunctive chemotherapy had a positive significant effect on DFI (P = .00011) and ST (P = .0003).ConclusionCanine scapular tumors can be treated effectively by scapulectomy and limb use is fair to excellent for most dogs. OSA was the most common scapular tumor. Overall prognosis for scapular OSA is similar to appendicular OSA at other sites and use of adjunctive chemotherapy prolonged the overall DFI and MST.
A test of the vulnerability model: temperament and temperament change as predictors of future mental disorders – the TRAILS study
Authors: Laceulle Odilia M. , Ormel Johan , Vollebergh Wilma A. M. , van Aken Marcel A.G. , Nederhof Esther 
Published: October 2013

BackgroundThis study aimed to test the vulnerability model of the relationship between temperament and mental disorders using a large sample of adolescents from the TRacking Adolescents Individual Lives' Survey (TRAILS). The vulnerability model argues that particular temperaments can place individuals at risk for the development of mental health problems. Importantly, the model may imply that not only baseline temperament predicts mental health problems prospectively, but additionally, that changes in temperament predict corresponding changes in risk for mental health problems.MethodsData were used from 1195 TRAILS participants. Adolescent temperament was assessed both at age 11 and at age 16. Onset of mental disorders between age 16 and 19 was assessed at age 19, by means of the World Health Organization Composite International Diagnostic Interview (WHO CIDI).ResultsResults showed that temperament at age 11 predicted future mental disorders, thereby providing support for the vulnerability model. Moreover, temperament change predicted future mental disorders above and beyond the effect of basal temperament. For example, an increase in frustration increased the risk of mental disorders proportionally.ConclusionThis study confirms, and extends, the vulnerability model. Consequences of both temperament and temperament change were general (e.g., changes in frustration predicted both internalizing and externalizing disorders) as well as dimension specific (e.g., changes in fear predicted internalizing but not externalizing disorders). These findings confirm previous studies, which showed that mental disorders have both unique and shared underlying temperamental risk factors.
The Cochrane Tobacco Addiction Group
Authors: Mehta Monaz 
Published: October 2013

AbstractThe Cochrane Tobacco Addiction Group produces up‐to‐date systematic reviews of interventions for the cessation and prevention of tobacco use. Many of our Cochrane Reviews have also been published in scientific journals. Our review prioritization schedule is informed by our group's experience and expertise as well as identifying topics for reviews via regular searches of current scientific literature and from other news sources, such as the Action on Smoking and Health updates. The Cochrane Register of Studies allows identification of new trials, which might be eligible for review updates. Everyday challenges include timely publishing and updating of our reviews, and ensuring compliance to Cochrane methodological expectations of Cochrane intervention review standards. We are grateful for the contributions of our authors and peer reviewers, with whom we aim to have close working and productive relationships. We look forward to continuing our contribution toward a reliable evidence base on interventions to combat tobacco addiction.
Cochrane Consumers and Communication Review Group: leading the field on health communication evidence
Authors: Prictor Megan , Hill Sophie 
Published: October 2013

AbstractThis paper presents an overview of the history and achievements of the Cochrane Consumers and Communication Review Group, part of the international Cochrane Collaboration. It surveys the Group's establishment and structure, the scope of its Cochrane Reviews and the growth in its publication output over its 16‐year history. The paper examines the Group's developmental work in interventions and outcomes related to patient communication and involvement, as well as methodological resources for review authors. It also outlines the Review Group's research partnerships with state, national and international agencies, particularly in the areas of chronic disease management, medicines use, public involvement, and vaccines communication. The Group's strong contribution to an evidence‐base for health communication and participation are acknowledged.
Cochrane systematic reviews in the field of addiction: past and future
Authors: Amato Laura , Mitrova Zuzana , Davoli Marina ,   Cochrane Drugs and Alcohol Group
Published: October 2013

AbstractBackground and ObjectiveThe Cochrane Drugs and Alcohol Group aims to produce, update, and disseminate systematic reviews on the prevention, treatment, and rehabilitation of problematic drug and alcohol use. This paper describes what the Group has done since the 1990s to produce evidence to guide policy, practice, and research.MethodWe analyze the coverage of topics by our reviews, the body of studies they have included, and the evidence produced.ResultsBy July 2013, the Group had published 67 reviews, with 376 authors from 25 different countries. These reviews included 906 studies, of 3061 studies considered for inclusion. Most (90%) included studies were randomized trials. Considering the ‘Implications for practice’ section of each review, 41% interventions were classified as ‘do it’, 15% as ‘do not do’, and 44% as ‘do only in research’. These proportions varied according to the type of substance of abuse studied. The proportion of ‘do it’ interventions were 46% for alcohol, 40% for opioids, 20% for psychostimulants, 40% for polydrugs, and 62% for prevention.ConclusionCochrane Reviews produced by the Drugs and Alcohol Group provide evidence on the effectiveness of several interventions, and identify areas of uncertainty where new research is needed.
Genetic characterization of a betanodavirus isolated from a clinical disease outbreak in farm‐raised tilapia Oreochromis niloticus (L.) in Thailand
Authors: Keawcharoen J , Techangamsuwan S , Ponpornpisit A , Lombardini E D , Patchimasiri T , Pirarat N 
Published: October 2013

AbstractBetanodavirus infection was diagnosed in larvae of farm‐raised tilapia Oreochromis niloticus (L.), in central Thailand. Extensive vacuolar degeneration and neuronal necrosis were observed in histological sections with positive immunohistochemical staining for betanodavirus. Molecular phylogenetic analysis was performed based on the nucleotide sequences (1333 bases) of the capsid protein gene. The virus strain was highly homologous (93.07–93.88%) and closely related to red‐spotted grouper nervous necrosis virus (RGNNV).
High‐Intensity Progressive Resistance Training Improves Flat‐Ground Walking in Older Adults with Symptomatic Peripheral Arterial Disease
Authors: Parmenter Belinda J. , Raymond Jacqueline , Dinnen Paul , Lusby Robert J. , Fiatarone Singh Maria A. 
Published: October 2013

ObjectivesTo assess the efficacy of whole‐body progressive resistance training (PRT) as a treatment for the symptoms of peripheral arterial disease (PAD) in older adults.DesignRandomized controlled pilot trial.SettingUniversity clinical weight training facility in Sydney, Australia.ParticipantsTwenty‐two older adults with symptomatic PAD.InterventionsThe efficacy of supervised whole‐body high‐intensity PRT (H‐PRT) with low‐intensity nonprogressive resistance training (L‐RT) and a usual care control group that performed unsupervised walking for 6 months was compared.MeasurementsPilot outcome measures included 6‐minute walk (6 MW) outcomes, body composition, dynamic muscle strength and endurance, and performance‐based tests of function.ResultsMean age was 71.1 ± 7.2. Mean ankle brachial index was 0.55 ± 0.13. Exercise adherence was similar in all groups (P = .29). H‐PRT (n = 8) improved total 6MW distance (mean difference (MD) 62.6 ± 58.0 m, P = .02) significantly more than L‐RT (n = 7; MD=−48.2 ± 67.6 m) and controls (n = 7; MD=−9.9 ± 52.9 m). Change in 6MW onset of claudication was significantly and independently related to change in bilateral calf endurance (correlation coefficient (r) = 0.65, P = .03), and change in 6MW distance was significantly and independently related to change in bilateral hip extensor endurance (r = 0.71, P = .02) in all groups.ConclusionH‐PRT significantly improved 6MW ability in older adults with intermittent claudication from PAD, whereas L‐RT and unsupervised walking did not. Improvement in walking ability was significantly related to improvements in bilateral calf and hip extensor endurance, supporting further investigations targeted at musculoskeletal impairment in this cohort.
Changes in Physical Performance in Older Women According to Presence and Treatment of Diabetes Mellitus
Authors: Lee Christine G. , Schwartz Ann V. , Yaffe Kristine , Hillier Teresa A. , LeBlanc Erin S. , Cawthon Peggy M. ,   the Study of Osteoporotic Fractures Research Group
Published: October 2013

ObjectivesTo determine whether older women with diabetes mellitus have a greater longitudinal decline in physical performance than those without and whether any decline differs according to insulin sensitizer use.DesignProspective cohort study.SettingBaltimore, Maryland; Minneapolis, Minnesota; Portland, Oregon; and the Monongahela, Pennsylvania.ParticipantsCommunity‐dwelling women (mean age 78.5 ± 3.6) enrolled in the Study of Osteoporotic Fractures in 1997–98 and restudied 4.9 ± 0.6 years later (N = 2,864).MeasurementsWomen were categorized as having no diabetes mellitus (n = 2,680) or having diabetes mellitus (n = 184). A prescription medication inventory was used to determine use of insulin sensitizers (metformin and thiazolidinedione). The outcomes were longitudinal changes in physical performance measures, including grip strength, usual walk speed, and rapid walk speed.ResultsEstimates from fully adjusted models showed that women with diabetes mellitus had greater declines in usual walk speed (−0.16 m/s, 95% confidence interval (CI) = −0.19 to −0.14) and rapid walk speed (−0.21 m/s, 95% CI = −0.24 to −0.17) than those without (usual walk speed −0.11 m/s, 95% CI = −0.12 to −0.11, P < .001; rapid walk speed −0.15 m/s, 95% CI = −0.16 to −0.14; P = .005). Women with diabetes mellitus taking insulin sensitizers had less decline in usual walk speed than those not taking insulin sensitizers (P < .001). Declines in grip strength did not differ significantly by diabetes mellitus status or insulin sensitizer use.ConclusionOlder women with diabetes mellitus have a greater decline in walk speed, but not grip strength, than older women without diabetes mellitus. Clinical studies in older adults to determine whether diabetes mellitus treatments such as insulin sensitizers can prevent loss in walk speed and mobility are needed.
Motor Learning Versus Standard Walking Exercise in Older Adults with Subclinical Gait Dysfunction: A Randomized Clinical Trial
Authors: Brach Jennifer S. , Van Swearingen Jessie M. , Perera Subashan , Wert David M. , Studenski Stephanie 
Published: October 2013

ObjectivesTo compare the effect of motor learning with that of standard exercise on measures of mobility and perceived function and disability.DesignSingle‐blind randomized trial.SettingUniversity research center.ParticipantsOlder adults (n = 40) with a mean age of 77.1 ± 6.0, normal walking speed (≥1.0 m/s), and impaired motor skills (Figure of 8 walk time >8 seconds).InterventionsThe motor learning program incorporated goal‐oriented stepping and walking to promote timing and coordination within the phases of the gait cycle. The standard program employed endurance training by treadmill walking. Both included strength training and were offered twice weekly for 1 hour for 12 weeks.MeasurementsPrimary outcomes were mobility performance (gait efficiency, motor skill in walking, gait speed, walking endurance); secondary outcomes were perceived function and disability (Late‐Life Function and Disability Instrument).ResultsThirty‐eight of 40 participants completed the trial (motor learning, n = 18; standard, n = 20). The motor learning group improved more than the standard group in gait speed (0.13 vs 0.05 m/s, P = .008) and motor skill (−2.2 vs −0.89 seconds, P < .001). Both groups improved in walking endurance (28.3 and 22.9 m, P = .14). Changes in gait efficiency and perceived function and disability were not different between the groups (P > .10).ConclusionIn older adults with subclinical gait dysfunction, motor learning exercise improved some parameters of mobility performance more than standard exercise.
Implementing an Evidence‐Based Fall Prevention Program in an Outpatient Clinical Setting
Authors: Li Fuzhong , Harmer Peter , Stock Ronald , Fitzgerald Kathleen , Stevens Judy , Gladieux Michele , Chou Li‐Shan , Carp Kenji , Voit Jan 
Published: October 2013

ObjectivesTo investigate the dissemination potential of a Tai Ji Quan–based program, previously shown to be efficacious for reducing risk of falls in older adults, through outpatient clinical settings.DesignA single‐group pre/post design in which participants attended a twice‐weekly Tai Ji Quan training program for 24 weeks.SettingCommunities in Lane County, Oregon.ParticipantsIndependently living individuals (N = 379) aged 65 and older.MeasurementsUsing the Reach, Effectiveness, Adoption, Implementation and Maintenance framework, the primary outcome was the proportion of participating healthcare providers who made referrals. Secondary outcomes were the proportion of referred individuals agreeing to participate and enrolling in the program, and measures of program implementation, maintenance, and effectiveness (on measures of falls, balance, gait, physical performance, and balance efficacy).ResultsOf the 252 providers invited to participate, 157 made referrals (62% adoption rate). Of 564 individuals referred, 379 (67% reach) enrolled in the program, which was successfully implemented in senior and community centers with good fidelity, 283 completed the program (75% retention), and 212 of these attended 75% or more of the 48 sessions. Participants reported a reduction in falls, with an incidence rate of 0.13 falls per person‐month, and showed significant improvement from baseline in all outcome measures. A 3‐month postintervention follow‐up indicated encouraging levels of program maintenance among providers, participants, and community centers.ConclusionHealthcare providers successfully implemented a protocol to refer individuals at risk of falling to a Tai Ji Quan–based program. The evidence‐based program appears readily scalable and exportable, with potential for substantial clinical and public health effect.
High‐Intensity Telemedicine‐Enhanced Acute Care for Older Adults: An Innovative Healthcare Delivery Model
Authors: Shah Manish N. , Gillespie Suzanne M. , Wood Nancy , Wasserman Erin B. , Nelson Dallas L. , Dozier Ann , McConnochie Kenneth M. 
Published: October 2013

Accessing timely acute medical care is a challenge for older adults. This article describes an innovative healthcare model that uses high‐intensity telemedicine services to provide rapid acute care for older adults without requiring them to leave their senior living community (SLC) residences. This program, based in a primary care geriatrics practice that cares for SLC residents, is designed to offer acute care through telemedicine for complaints that are felt to need attention before the next available outpatient visit but not to require emergency department (ED) resources. This option gives residents access to care in their residence. Measures used to evaluate the program include successful completion of telemedicine visits, satisfaction of residents and caregivers with telemedicine care, and site of care that would have been recommended had telemedicine been unavailable. During the first 2 years of the program's operation, 281 of 301 requested telemedicine visits were completed successfully. Twelve residents were sent to an ED for care after the telemedicine visit. Ninety‐four percent of residents reported being satisfied or very satisfied with telemedicine care. Had telemedicine not been available, residents would have been sent to an ED (48.1%) or urgent care center (27.0%) or been scheduled for an outpatient visit (24.4%). The project demonstrated that high‐intensity telemedicine services for acute illnesses are feasible and acceptable and can provide definitive care without requiring ED or urgent care use. Continuation of the program will require evaluation demonstrating equal or better resident‐level outcomes and the development of sustainable business models.
BAK1 Directly Regulates Brassinosteroid Perception and BRI1 Activation
Authors: He Kai , Xu Shengbao , Li Jia 
Published: October 2013

AbstractPlants utilize plasma membrane‐localized receptor‐like kinases (RLKs) to sense extracellular signals to coordinate growth, development, and innate immune responses. BAK1 regulates multiple signaling pathways acting as a co‐receptor of several distinct ligand‐binding RLKs. It has been debated whether BAK1 serves as an essential regulatory component or only a signal amplifier without pathway specificity. This issue has been clarified recently. Genetic and structural analyses indicated that BAK1 and its homologs play indispensible roles in mediating brassinosteroid (BR) signaling pathway by directly perceiving the ligand BR and activating the receptor of BR, BRI1. The mechanism revealed by these studies now serves as a paradigm for how a pair of RLKs can function together in ligand binding and subsequent initiation of signaling.imageJia Li (Corresponding author)
Applying the job demands–resources model to migrant workers: Exploring how and when geographical distance increases quit propensity
Authors: Qin Xin , Hom Peter , Xu Minya , Ju Dong 
Published: October 2013

We extend the job demands–resources model to explain how and when rural migrants who work far from their families and provincial hometowns are more likely to leave jobs. Through two studies, we found that the geographical distance between employees' workplace and home village, representing a proxy for a wide range of migration demands and resources, may engender higher turnover intentions under some conditions. Specifically, employees' psychological contract fulfilment diminished positive associations between geographical distance and turnover intentions. Moreover, we demonstrated emotional exhaustion as an explanatory mechanism underlying the relationship between geographical distance and turnover intentions. Our investigation thus yielded greater insight into rural migrants' quit propensity by identifying geographical distance (a proxy for migration‐based demands and resources) as a key driver whose influence is mediated by emotional exhaustion and moderated by psychological contract fulfilment.Practitioner points

Proposed and found that geographical distance between migrants' workplace and hometown was a proxy for various (increased) demands and (decreased) resources that are intrinsically tied to employment location rather than job content. Through increasing emotional exhaustion, geographical distance may lead to high turnover intentions among workers under certain conditions (i.e., when psychological contract was violated).

When export‐processing zones organizations consider keeping employees, they must address how long geographical distance from home can exhaust migrants' mental and physical resources and therefore engender turnover through energy depletion (i.e., a state of exhaustion). Provided that geographical distance is an unavoidable problem for organizations, firms can lessen the psychological and family costs of geographical distance through certain ways. Specifically, organizations can better fulfil psychological contracts, which can increase emotional attachment to organizations and thus lessen emotional exhaustion due to long family separations.
Consumer Perception of Dry‐Cured Ham – A Cross‐Cultural Study in Italy, Norway and Spain
Authors: Hersleth Margrethe , Næs Tormod , Guerrero Luis , Claret Anna , Recchia Annamaria , Dinnella Caterina , Monteleone Erminio 
Published: October 2013

AbstractThe main aim of this study was to explore Italian, Norwegian and Spanish consumers' sensory perception of dry‐cured ham. Six samples of dry‐cured ham, two Italian, two Norwegian and two Spanish, were profiled by trained panels in the three countries. Consumer samples of 30 respondents in each country elicited sensory descriptors for the six hams and subsequently rated the intensity of individual descriptors. Perceptual consensus product maps were derived from the Generalized Procrustes Analysis.Results revealed that all the four sensory modalities are important for the perception of dry‐cured ham and demonstrated a relatively large variation in vocabulary used for sensory description of hams in the three countries. Because of less familiarity with dry‐cured ham and a different eating culture, Norwegian consumers have a relatively limited vocabulary and do not agree well on the concepts for given descriptors. Attributes that were most frequently used across panels and countries were: red color, marbling, ripe/cured flavor and odor, saltiness, sweetness, firmness and tenderness.Practical ApplicationsFood preferences and description of sensory properties in foods vary across cultures. Considering the global character of today's food market, it is crucial for the food industry to use proper and meaningful words to communicate their products. Moreover, communication of sensory product attributes to consumers creates both sensory‐based and hedonic‐based expectations to the sensory quality. It is essential that these expectations are met during consumers eating experience.Finding in this study demonstrate a relatively large variation in vocabulary used for description of dry‐cured ham in Norway, Italy and Spain. This is mainly due to differences in familiarity with the product and different cultural eating experiences. Accordingly, it is important to tailor the communication of products according to the relevant consumer segment.