bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pre‐implementation context and implementation approach for a nursing and midwifery clinician researcher career pathway: A qualitative study
Authors: Johnson Maree , Straiton Nicola , Ferguson Caleb , Mcinnes Elizabeth , Thornton Anna , Everett Browyn , Tuqiri Karen , Meedya Shahla , Hackett Kate , Cruickshank Marilyn , Fry Margaret , Perry Lin , Sheppard‐Law Suzanne , Hosie Annmarie , Inglis Sally , Mcerlean Gemma , Debono Deborah , Fernandez Ritin , Wynne Rochelle , Chow Josephine , Hickman Louise , Del Olmo Gail , Middleton Sandy ,   SPHERE Nursing and Midwifery Implementation Science Academy
Published: July 2024

AbstractAimTo describe the pre‐implementation context and implementation approach, for a clinician researcher career pathway.BackgroundClinician researchers across all health disciplines are emerging to radically influence practice change and improve patient outcomes. Yet, to date, there are limited clinician researcher career pathways embedded in clinical practice for nurses and midwives.MethodsA qualitative descriptive design was used.Data SourcesData were collected from four online focus groups and four interviews of health consumers, nursing and midwifery clinicians, and nursing unit managers (N = 20) between July 2022 and September 2023.ResultsThematic and content analysis identified themes/categories relating to: Research in health professionals' roles and nursing and midwifery, and Research activity and culture (context); with implementation approaches within coherence, cognitive participation, collective action and reflexive monitoring (Normalization Process Theory).ConclusionsThe Pathway was perceived to meet organizational objectives with the potential to create significant cultural change in nursing and midwifery. Backfilling of protected research time was essential.Implications for the Profession and/or Patient CareThe Pathway was seen as an instrument to empower staff, foster staff retention and extend research opportunities to every nurse and midwife, while improving patient experiences and outcomes.ImpactClinicians, consumers and managers fully supported the implementation of clinician researchers with this Pathway. The Pathway could engage all clinicians in evidence‐based practice with a clinician researcher leader, effect practice change with colleagues and enhance patient outcomes.Reporting MethodThis study adheres to relevant EQUATOR guidelines using the COREG checklist.Patient or Public ContributionHealth consumers involved in this research as participants, did not contribute to the design or conduct of the study, analysis or interpretation of the data, or in the preparation of the manuscript.
Association between biological ageing and periodontitis: Evidence from a cross‐sectional survey and multi‐omics Mendelian randomization analysis
Authors: Huang Zhendong , Peng Simin , Cen Ting , Wang Xiaoxuan , Ma Li , Cao Zhengguo 
Published: July 2024

AbstractAimTo investigate the relationship and potential causality between biological ageing and periodontitis.Materials and MethodsWe obtained the National Health and Nutrition Examination Survey (NHANES) and genome‐wide association study (GWAS) summary statistics as well as single‐cell sequencing data. Multivariate regression analysis based on cross‐sectional data, Mendelian randomization (MR) and multi‐omics integration analysis were employed to explore the causal association and potential molecular mechanisms between biological ageing and periodontitis. Additionally, two‐step MR mediation analysis explored the risk factors in biological ageing‐mediated periodontitis.ResultsWe analysed data from 3189 participants in the NHANES data and found that higher biological age was associated with increased risk of periodontitis. MR analyses revealed causal associations between biological age measures and periodontitis risk. Frailty (odds ratio [OR] = 2.08, 95% confidence interval [CI]: 1.04–4.18, p = .039) and GrimAge acceleration (OR = 1.16, 95% CI: 1.01–1.32, p = .033) were causally associated with periodontitis risk, and these results were validated in a large‐scale meta‐periodontitis GWAS dataset. Additionally, the risk effects of body mass index, waist circumference and lifetime smoking on periodontitis were partially mediated by frailty and GrimAge acceleration.ConclusionsEvidence from cross‐sectional survey and MR analysis suggests that biological ageing increases the risk of periodontitis. Additionally, improving the associated risk factors can help prevent both ageing and periodontitis.
Developing evidence‐based medication therapy management tools for psychiatric nurses: An evaluative qualitative case study
Authors: Bulut Melisa , Yüksel Çiğdem 
Published: July 2024

AbstractRationale, Aims and ObjectivesClinical use of psychotropic medications involves diverse risks, addressable by nursing interventions. The research had a dual purpose: developing an “Evidence‐Based Medication Therapy Management Guideline” and a “Medication Administration‐Tracking Chart” and evaluating their use through an evaluative case study.MethodsEvidence‐based guideline and chart development and evaluative case study. Initially, Evidence‐Based Medication Therapy Management Guideline and Medication Administration Tracking Chart for managing medication in a psychiatric unit were developed. Subsequently, their efficacy was evaluated in a case study involving 10 participating nurses used in the psychiatric unit with 123‐bed of a training and research hospital in Turkey. Data was collected through personal forms, interviews, medication charts, and researcher observations, and the analysis employed Merriam's case study method.ResultsThree themes (inception, implementation, termination, and sustainers) and 12 sub‐themes emerged. Nurses stated that the research tools filled their information gaps, enhancing the medication therapy management process's effectiveness and safety, improving nursing care quality and continuity, and benefiting patient outcomes. Nurses expressed a desire to consistently use the tools in the unit and provided suggestions.ConclusionNurses highlighted the tools' potential to enhance medication safety, psychiatric care, and patient outcomes. However, their stance on using evidence‐based tools revealed an approach/avoidance conflict, balancing benefits and barriers. Experience emerged as a hindrance in embracing evidence‐based clinical tools. This study is among the first to comprehensively develop evidence‐based medication management guideline and administration‐tracking chart for psychiatric nurses globally and in our country. Routine use of the tools is expected to enhance nurses' expertise in psychotropic medication management, leading to improved patient outcomes in medication‐related aspects.
Topical retinoids: Novel derivatives, nano lipid‐based carriers, and combinations to improve chemical instability and skin irritation
Authors: Zhong Jiangming , Zhao Nan , Song Qingle , Du Zhiyun , Shu Peng 
Published: July 2024

AbstractBackgroundRetinoids, defined as synthetic or natural derivatives of vitamin A, have been extensively studied as anti‐aging molecules that are widely applied in cosmetics. However, due to their physicochemical property, retinoids are highly unstable and extremely sensitive to light, oxygen, and temperature. Moreover, topical application of retinoids often leads to cutaneous irritation. These instabilities and irritant properties of retinoids limit their application in cosmetic and pharmaceutical products.AimOur study aimed to provide a systematic review to summarize the mechanisms underlying the instability and irritant properties of retinoids, as well as recent developments in addressing these challenges.MethodsA comprehensive PubMed search was conducted using the following keywords: retinoids, chemical instability, skin irritation, retinoid derivatives, nano lipid‐based carriers, liposomes, penetration‐enhancer vesicles, ethosomes, niosomes, nanoemulsions, solid lipid nanoparticles, vitamins, soothing and hydrating agents, antioxidants and metal chelator and retinol combinations. Relevant researches published between 1968 and 2023 and studies related to these reports were reviewed.ResultsThe development of new retinoid derivatives, the utilization of new delivery systems like nano lipid‐based carriers and the combination with other compounds like vitamins, soothing agents, antioxidants and metal chelator have been explored to improve the stability, bioavailability, and toxicity of the retinoid family.ConclusionsThrough advancements in formulation techniques, structure modification of retinoid derivatives and development of novel nano lipid‐based carriers, the chemical instability and skin irritation of retinoids has been mitigated, ensuring their efficacy and potency over extended periods.
Nasal filling guided by high frequency ultrasound: Reducing risks
Authors: Bravo Bruna Souza Felix , Carvalho Raquel De Melo , Elias Mariana Calomeni , Nobre Camila Silveira , Alves Gabriel Leal Telino , Bravo Leonardo Gonçalves , de Almeida Thamires Silva Cavalcante 
Published: July 2024

AbstractBackgroundGiven the significant increase in the quantity of cosmetic procedures utilizing hyaluronic acid fillers, including in the nasal region, the initial evaluation of patients using high frequency ultrasound becomes a crucial instrument in evaluating and handling nonsurgical rhinoplasty.AimsThe aim of this article is to introduce an assessment methodology for nasal filling guided by high frequency ultrasound.Patients/MethodsA prospective and single‐center study was conducted with 12 Latin American patients. The patients underwent nasal filling with hyaluronic acid following high power ultrasound mapping.Results and ConclusionsIn the evaluation of the GAIS scale, all patients reported improvement with the treatment. No infections, nodules, ischemia, or other relevant adverse effects were noted. Real‐time ultrasound‐guided filler techniques have been developed to reduce the risk of vascular compromise, confirming the distribution pattern of blood vessels. It's also crucial to visualize the cannula at the same moment as the vessels, even if the previous vascular mapping was performed. Therefore, the utilization of high frequency ultrasound can act as a pivotal tool in augmenting procedure safety.
Reflections on Psychological Critical Race Theory (PCRT) as a framework for disrupting racism in pursuit of social justice
Authors: Jones James M. 
Published: July 2024

AbstractPsychological Critical Race Theory (PCRT) was introduced in 1998. PCRT illustrates the integral connection of psychological research and theory to the legal framework of Critical Race Theory (CRT). Five tenets of PCRT were described: (1) Spontaneous and persistent influence of race; (2) Fairness is derived from divergent racial experiences; (3) Asymmetrical consequences of racial policies; (4) Paradoxes of racial diversity; and (5) Racial identity requires a multidimensional approach. These tenets are reviewed and updated. A new set of seven PCRT principles are proposed that provide a broad framework within which to examine the PCRT concept and its role in reframing critical approaches to racial justice. Principle 1: Race and culture make each other up; Principle 2: Meaning Matters; Principle 3: Multilevel analysis is critical to unraveling Systemic Racism; Principle 4: Activism is a lever for social change; Principle 5: Power drives racial inequality; Principle 6: Storytelling disrupts status quo narratives; Principle 7: Diversity does not ameliorate systemic racism. PCRT is a 100‐year enterprise of psychological science, offering a complex and comprehensive framework for understanding and ameliorating persistent racial inequality. The comprehensive network of ideas, methods, goals, and strategies can engage and guide this work for years to come.
Provision of bubble continuous positive airway pressure for the stabilisation of extremely and very preterm infants after birth: A single‐centre experience
Authors: Legge Nele , Fitzgerald Dominic , Popat Himanshu 
Published: July 2024

AimTo describe the effect of resuscitation with bubble CPAP (bCPAP) versus T‐piece device at birth on early clinical parameters and hospital outcomes in infants born <32 weeks gestation.MethodsThis is a single‐centre pre‐ and post‐implementation study comparing outcomes in two epochs. In epoch 1 (1 July 2013–31 December 2014), infants were managed with non‐humidified gas using Neopuff® T‐piece devices to support breathing after birth. In epoch 2 (1 March 2020–31 December 2021), routine application of bCPAP with humidified gas was introduced at birth.ResultsThree hundred fifty‐seven patients were included (176 epoch 1, 181 epoch 2). The mean gestational age was 28 ± 2 weeks. The demographics of the two epochs were comparable. There were significant improvements in outcomes of infants in epoch 2 with less infants intubated at delivery (16% vs. 4%, P ≤ 0.001), improved 5 min Apgar (7 vs. 8, P ≤ 0.001), reduced need for ventilation (21% vs. 8.8%, P ≤ 0.001), duration of ventilation in the first 72 h (9.6 vs. 4.6 h) and mortality (10.8% vs. 1.7%, P ≤ 0.001). There was, increased incidence of chronic lung disease (30% vs. 55%, P = 0.02) but no increase in infants discharged on oxygen (3.8% vs. 5%, P = 0.25). Similar findings were observed in a subgroup of infants born <25 weeks' gestation with no increase in the incidence of CLD.ConclusionIntroducing application of bCPAP from the first breaths in infants <32 weeks' gestation was associated with better short‐term outcomes and mortality, albeit with increased incidence of CLD. The subgroup of infants born <25 weeks' gestation showed similar change in outcomes, with no increase in CLD.
Assessing the combination efficiency of some unconventional feed resources with concentrates and Chloris gayana grass in mitigating ruminal methane production in vitro
Authors: Melesse Aberra , Steingass Herbert , Holstein Julia , Titze Natascha , Rodehutscord Markus 
Published: July 2024

AbstractIn a preliminary in vitro study, leaves of Acacia nilotica, Prosopis juliflora, Cajanus cajan, Leucaena leucocephala and seed kernel of Mangifera indica were identified as potential candidates in mitigating ruminal methane (CH4) production. The objective of the current study was to investigate the combination efficiency of these unconventional feeds with concentrate mix (CM) or Chloris gayana grass in CH4 reduction. Two feed combinations in different proportions were incubated in vitro with buffered rumen fluid at Hohenheim Gas test. In combination 1, C. gayana and CM were included as basal substrates, while in combination 2, A. nilotica, P. juliflora, C. cajan, L. leucocephala or M. indica seed kernel were included as CH4 reducing supplements at different proportions. The CH4 reducing potentials of feed combinations were presented as the ratio of CH4 to net gas production and expressed as percentage (pCH4). The pCH4 for CM and C. gayana was 16.7% and 16.9%, respectively, while it ranged from 3.18% in A. nilotica to 13.1% in C. cajan. The pCH4 was reduced (p < 0.05) from 14.6% to 9.39% when A. nilotica was combined with CM. In combination of L. leucocephala or C. cajan with CM, the pCH4 (p < 0.05) was reduced from 16.5% and 16.6% with the lowest proportion to 15.1% and 15.2% with the highest inclusion rate respectively. The combination of C. gayana with L. leucocephala or C. cajan reduced (p < 0.05) the pCH4 from 16.3% and 16.4% to 15.1% and 14.9% respectively. The pCH4 was reduced (p < 0.05) from 13.4% to 7.60% when A. nilotica was combined with C. gayana. Estimated digestible organic matter (dOM) and metabolizable energy (ME) increased (p < 0.05) with increasing proportions of M. indica seed kernel with CM or C. gayana. In conclusion, the combination of the basal substrates with unconventional supplements resulted in CH4 reduction without affecting the dOM and ME at lower inclusion rates. Animal‐based experiments await to validate in vitro findings.
Unlocking the power of diversity for supply chain knowledge: Is pluralism in theorizing styles the key?
Authors: Cornelissen Joep , Stephens Victoria , Matthews Lee 
Published: July 2024

AbstractThe authors reflect on the opportunities for diversity in supply chain research by examining the prevalent modes of theorizing in the field. This examination focuses on identifying common styles of theorizing in supply chain management research, which are defined as specific modes of reasoning to make inferences about supply chain phenomena. Armed with this definition, the authors elaborate how research in the field has for the most part hinged on a propositional style as a common base for theorizing and theoretical contributions. The analysis that is provided emphasizes the limits of this style, particularly when it is considered as the preferred form for all theoretical contributions. The authors, in turn, make the case for a pluralistic system of knowledge production that supports the use of multiple theorizing styles that, when used alongside one another in a coordinated or co‐oriented manner, will lead to a better understanding of supply chain management phenomena.
Consciousness in non‐REM‐parasomnia episodes
Authors: Siclari Francesca 
Published: July 2024

SummarySleepwalking and related parasomnias are thought to result from incomplete awakenings out of non‐rapid eye movement (non‐REM) sleep. Non‐REM parasomnia behaviours have been described as unconscious and automatic, or related to vivid, dream‐like conscious experiences. Similarly, some observations have suggested that patients are unresponsive during episodes, while others that they can interact with their surroundings. To better grasp and characterise the full spectrum of consciousness and environmental (dis)connection associated with behavioural episodes, 35 adult patients with non‐REM sleep parasomnias were interviewed in‐depth about their experiences. The level of consciousness during parasomnia episodes was reported to be variable both within and between individuals, ranging from minimal or absent consciousness and largely automatic behaviours (frequently/always present in 36% of patients) to preserved conscious experiences characterised by delusional thinking of varying degrees of specificity (65%), often about impending danger, variably formed, uni‐ or multisensory hallucinations (53%), impaired insight (77%), negative emotions (75%), and variable, but often pronounced, amnesia (30%). Patients described their experiences as a dream scene during which they felt awake (“awake dreaming”). The surroundings were either realistically perceived, misinterpreted (in the form of perceptual illusions or misidentifications of people), or entirely hallucinated as a function of the prevailing delusion. These observations suggest that the level of consciousness, amnesia and sensory disconnection during non‐REM parasomnia episodes is variable and graded. In their full‐fledged expression, non‐REM parasomnia experiences feature several core features of dreams. They therefore represent a valuable model for the study of consciousness, sleep‐related sensory disconnection and dreaming.
Research on commercial milk formulas for young children: A scoping review
Authors: Cavalcanti Maria Birman , Silva Isabela da Costa Gaspar da , Lamarca Fernando , de Castro Inês Rugani Ribeiro 
Published: July 2024

AbstractA scoping review of publications about commercial milk formulas intended for or consumed by children 12–36 months (CMF 12–36) was conducted. This review aimed to comprehensively map the existing literature, identify key concepts in the field and understand its evolution through time. A total of 3329 articles were screened and 220 were included, published between 1986 and 2024. Most works were published after 2016 (70.0%) and in high‐income countries (71.8%). Original studies were the vast majority (81.8%) of publications. Most publications dealt with feeding practices or analysed the composition and/or contamination of specific products (44.1% and 35.9%), but since the late 2000s, publications about marketing, policy, legislation, and consumer perception started to appear. Most published works (65.5%) did not focus exclusively on CMF 12–36 and included formulas for other demographics or other foods. About half of the works (55.5%) did not consider CMF 12–36 to be a breast milk substitute. We found 81 distinct product denominations used to refer to CMF 12–36, Growing Up Milk was the most common (25.9%). CMF industry was involved in 41.8% of all analysed works, and industry participation and funding were not always clearly informed (22.5% lacked a conflict of interest statement, and 25.5% did not present any information about funding). In the last decade, publications about CMF 12–36 have increased in volume and diversified in scope and subject matter. CMF‐industry participation has always been and still is present in the field, so possible vested interests should be taken into account when appreciating the literature.
On the road to losing connectivity: Faecal samples provide genome‐wide insights into anthropogenic impacts on two large herbivore species in central India
Authors: Tyagi Abhinav , Yadav Nidhi , Pandit Awadhesh , Ramakrishnan Uma 
Published: July 2024

AbstractHumans have impacted most of the planet, and the ensuing fragmentation results in small, isolated habitat patches posing a risk of genetic diversity loss, inbreeding, and genetic load. Understanding how natural and anthropogenic landscape features affect gene flow among habitat patches is critical for maintaining connectivity. Genome‐wide data are required to comprehend the impacts of recent fragmentation, which can be challenging when only non‐invasive samples are available. Here, we build upon advancements in conservation genomics to address connectivity of two large herbivores, gaur (Bos gaurus) and sambar (Rusa unicolor) in central India. Given their habitat associations, we expected these species to respond similarly to habitat fragmentation. We used faecal‐DNA and methylation‐based host‐DNA enrichment with modified ddRAD protocol to generate genome‐wide single‐nucleotide polymorphism (SNP) data for 124 gaur and 99 sambar individuals. Our findings reveal that gaur populations in central India are fragmented, displaying high genetic differentiation, with drift significantly affecting small populations like Umred Karhandla Wildlife Sanctuary. Although sambar shows low genetic structure, another small population, Bor Tiger Reserve is genetically differentiated. Our results suggest that although land cover change and roads restrict animal movement, the extent of this impact varies across the two species. We show that different species respond differently to landscape features, even with similar habitat associations. We highlight small and isolated populations requiring urgent conservation intervention. Such multi‐species approaches enhance our understanding of cross‐species connectivity patterns. We suggest shifting from single‐species to multi‐species holistic conservation approach in rapidly developing landscapes to better manage co‐occurring endangered species.