bluuebunny/crossref_metadata_2025_split huggingface dataset:
A compact rotating dilution refrigerator
Authors: Fear M. J. , Walmsley P. M. , Chorlton D. A. , Zmeev D. E. , Gillott S. J. , Sellers M. C. , Richardson P. P. , Agrawal H. , Batey G. , Golov A. I. 
Published: October 2013

We describe the design and performance of a new rotating dilution refrigerator that will primarily be used for investigating the dynamics of quantized vortices in superfluid 4He. All equipment required to operate the refrigerator and perform experimental measurements is mounted on two synchronously driven, but mechanically decoupled, rotating carousels. The design allows for relative simplicity of operation and maintenance and occupies a minimal amount of space in the laboratory. Only two connections between the laboratory and rotating frames are required for the transmission of electrical power and helium gas recovery. Measurements on the stability of rotation show that rotation is smooth to around 10−3 rad s−1 up to angular velocities in excess of 2.5 rad s−1. The behavior of a high-Q mechanical resonator during rapid changes in rotation has also been investigated.
Regulation of estrogen receptor α by histone methyltransferase SMYD2-mediated protein methylation
Authors: Zhang Xi , Tanaka Kaori , Yan Jiusheng , Li Jing , Peng Danni , Jiang Yuanyuan , Yang Zhe , Barton Michelle C. , Wen Hong , Shi Xiaobing 
Published: October 2013

Significance
Histone-modifying enzymes play an important role in regulating chromatin-associated processes such as transcription. In addition to modifying histones, these enzymes control gene expression through modifying nonhistone proteins, including transcription factors. In this study, we show that SET and MYND domain containing 2 (SMYD2), a histone H3K4 and H3K36 methyltransferase, directly methylates estrogen receptor alpha (ERα) protein at lysine 266 and represses ERα transactivation activity. Upon estrogen activation, this repressive mark is relieved by the histone H3K4 demethylase lysine-specific demethylase 1, followed by p300/cAMP response element-binding protein–binding protein (CBP)-mediated protein acetylation. Our study suggests that the cross-talk of distinct posttranslational modifications in the hinge region of ERα plays an important role in fine tuning the functions of ERα at chromatin in hormone response.
DNA conformations in mismatch repair probed in solution by X-ray scattering from gold nanocrystals
Authors: Hura Greg L. , Tsai Chi-Lin , Claridge Shelley A. , Mendillo Marc L. , Smith Jessica M. , Williams Gareth J. , Mastroianni Alexander J. , Alivisatos A. Paul , Putnam Christopher D. , Kolodner Richard D. , Tainer John A. 
Published: October 2013

Significance
We developed and applied nanogold labels for DNA complexes with proteins examined by small angle X-ray scattering (SAXS) to follow DNA conformations acting in error detection by the mismatch repair (MMR) system in solution. This technique can examine short or long pieces of DNA and in most solution conditions, including those closest to cellular environments. Thus, we expect the technique to be useful for many biologically important systems involving DNA complexes and conformations. Specifically, we reveal DNA bending followed by straightening by the repair protein MutS at the site of a mismatch as a suitable mechanism for error detection and signaling needed to avoid mutations and cancers and to control microbial stability and evolution in response to environmental stress.
Human cytomegalovirus tegument protein pp150 acts as a cyclin A2–CDK-dependent sensor of the host cell cycle and differentiation state
Authors: Bogdanow Boris , Weisbach Henry , von Einem Jens , Straschewski Sarah , Voigt Sebastian , Winkler Michael , Hagemeier Christian , Wiebusch Lüder 
Published: October 2013

Significance
Depending on the host cell type and differentiation status, herpesviruses establish different modes of infection to either maintain or replicate their genomes. How viruses discriminate between individual host cell environments upon infection is poorly understood. Here we identify a viral sensor mechanism that restricts human cytomegalovirus (HCMV) replication to the G0/G1 phase of the cell division cycle and to differentiated cells. The mechanism is based on the HCMV tegument 150-kDa phosphoprotein which enters the cell as a constituent of the virus particle, interacts with cyclin A2, and blocks the onset of viral lytic gene expression when cyclin A2-dependent kinase activity is high. This suggests a scenario where specific tegument–host interactions enable herpesviruses to select sites of silent or productive infection.
Diaphragmatic Function Is Preserved during Severe Hemorrhagic Shock in the Rat
Authors: Carreira Serge , Lê Dinh Matthieu , Soubeyrand Marc , Poloujadoff Marie-Pierre , Riou Bruno , Similowski Thomas , Coirault Catherine , Demoule Alexandre 
Published: October 2013

Abstract

Background:
Acute diaphragmatic dysfunction has been reported in septic and cardiogenic shock, but few data are available concerning the effect of hemorrhagic shock on diaphragmatic function. The authors examined the impact of a hemorrhagic shock on the diaphragm.

Methods:
Four parallel groups of adult rats were submitted to hemorrhagic shock induced by controlled exsanguination targeting a mean arterial blood pressure of 30 mmHg for 1 h, followed by a 1-h fluid resuscitation with either saline or shed blood targeting a mean arterial blood pressure of 80 mmHg. Diaphragm and soleus strip contractility was measured in vitro. Blood flow in the muscle microcirculation was measured in vivo using a Laser Doppler technique. Muscle proinflammatory cytokine concentrations were also measured.

Results:
Hemorrhagic shock was characterized by a decrease in mean arterial blood pressure to 34 ± 5 mmHg (−77 ± 4%; P< 0.05) and high plasma lactate levels (7.6 ± 0.9 mM; P < 0.05). Although tetanic tension of the diaphragm was not altered, hemorrhagic shock induced dramatic impairment of tetanic tension of the soleus (−40 ± 19%; P < 0.01), whereas proinflammatory cytokine levels were low and not different between the two muscles. Resuscitation with either blood or saline did not further modify either diaphragm or soleus performance and proinflammatory cytokine levels. The shock-induced decrease in blood flow was much more pronounced in the soleus than in the diaphragm (−75 ± 13% vs. −17 ± 10%; P = 0.02), and a significant interaction was observed between shock and muscle (P < 0.001).

Conclusion:
Diaphragm performance is preserved during hemorrhagic shock, whereas soleus performance is impaired, with no further impact of either blood or saline fluid resuscitation.
Benchmarking award winning health care organizations in the USA
Authors: Welborn Cliff , Bullington Kimball 
Published: October 2013

Purpose
– The purpose of this study is to benchmark the use of process improvement techniques among US health care organizations that won the Malcolm Baldrige National Quality Award.

Design/methodology/approach
– The applications from 13 Baldrige award winning health care organizations were researched to determine which process improvement techniques were used most frequently to guide their operations.

Findings
– The results from this study identify several best practices in process improvement techniques. Furthermore, the study pinpoints in which aspect of performance that a process improvement technique is most likely to be used.

Research limitations/implications
– Only applications from organizations winning the Baldrige award have been studied. The identity and application for organizations that do not win the award are not released to the public. Statistical analysis of the data is limited to the relatively small number (13) of award winners.

Practical implications
– The results clearly show that there are certain process improvement techniques used by a majority of the Baldrige winners. It is not possible to guarantee that the use of these same techniques by other health care organizations will result in performance improvement, only that the winners used the techniques and have achieved a high level of performance. The results identify processes for further benchmarking studies.

Originality/value
– The process improvement techniques identified in this study have been used by successful health care organizations. This information may be useful to other health care organizations when deciding on which process improvement techniques to pursue in order to improve their own performance. While the Baldrige award process has driven benchmarking efforts, this study uses the Baldrige process to identify benchmarking opportunities for process improvement in health care organizations.
Implementing CAF in public administration
Authors: A. Vakalopoulou Melpomeni , Tsiotras George , Gotzamani Katerina 
Published: October 2013

Purpose
– The purpose of this paper is to stimulate interest in the use of the Common Assessment Framework (CAF), a self-evaluation quality tool for the public sector, to disseminate relevant experiences from CAF implementation in Europe, to offer ideas about CAF optimization and to provide a basis and direction for further improvement.

Design/methodology/approach
– The methodology that is followed in the paper is based on the study of best practices (BP) of CAF implementation in European public administrations. The BP were selected in order to cover a wide range of political fields and to prove that CAF can be used by organizations in all parts of the public sector with different characteristics of size and structure.

Findings
– Studying relevant examples leads to the conclusion that effective CAF implementation can improve the performance of public administration and help establish a quality philosophy. The paper shows that CAF is a tool that can be easily modified and adapted to the organizations' special needs and characteristics.

Practical implications
– The study of the selected cases and the related information that is presented in this paper helps to disseminate relevant experiences from CAF implementation in Europe. It offers managers of the public sector ideas and helps on how to implement the CAF model, by providing real examples of organizations that have implemented it. It also helps them understand the benefits from CAF implementation, as well as the obstacles and barriers that may be faced, in order to be better prepared for its successful implementation.

Originality/value
– The value of this paper lies in the identification and presentation of several ideas and tools which have been successfully developed by European organizations and may as well be implemented by others. Ideas about modifying CAF and adjusting it into the uniqueness of every organization can be obtained only through careful study and analysis of its implementation.
The effect of international experience on the degree of SME insidership in newly opened business networks
Authors: Hilmersson Mikael 
Published: October 2013

Purpose
– The purpose of this study is to develop internationalization process theory by examining the relationship between small- and medium-sized enterprises (SMEs) international experience and their degree of insidership in newly opened business networks.

Design/methodology/approach
– The study applies a quantitative approach. Data were collected on-site at 203 SMEs having entered the Baltic States, Poland, Russia and China. The data are analysed with structural equation modeling in SmartPLS.

Findings
– The paper reveals that international experience is positively associated with both the country and customer experience in the newly opened business network. Country experience, in turn, is strongly associated with a firm's degree of insidership in the business network. Conflicting with the hypothesized model, no support is found for the direct relationship between international experience and insidership. Nor does the analysis reveal any significant relationship between a firm's customer experience, in terms of variation, in the newly opened business network and the degree of insidership in the network.

Research limitations/implications
– The paper empirically discriminates different types of international experience derived from theory and examines their relationship with the degree of firm insidership in newly opened business networks.

Originality/value
– Theoretically this paper advances internationalization process theory by developing its network aspect as well as discriminating different experience types and their role in predicting network insidership in newly opened business networks.
Tough decisions: phasing out a popular option to maintain overall service viability
Authors: Herrera Kevin 
Published: October 2013

Purpose
– The purpose of this paper is to describe the University of Mississippi Libraries' experience in implementing a printing cost-recovery service, unexpectedly finding itself managing a large number of cash transactions, and ultimately – many years later – eliminating the cash payment option.

Design/methodology/approach
– An analysis of print logs was completed along with a study of the various costs (hardware/software, personnel, consumables, and transaction fees) in order to examine the total operating costs of the system.

Findings
– Personnel costs related to cash transactions were the greatest expense related to operating the system. Increasing cash-handling costs were driving up the overall operating costs of the public print system. After the cash payment option was eliminated, overall print volume decreased, but the corresponding decrease in operating expenses meant that the library had new opportunities for expanding the and enhancing the service.

Originality/value
– This case study could be of benefit to others looking to do a similar analysis of fee-based services – particularly high-volume services where cash is a common method of payment.
Is the chain of command working for you?
Authors: A. Crumpton Michael 
Published: October 2013

Purpose
– The purpose of this paper is to discuss the importance of having a chain of command strategy, in particular with staff repurposing activities.

Design/methodology/approach
– This paper refers to field literature to support this concept.

Findings
– The literature and readings cited demonstrate need and consideration.

Originality/value
– The paper highlights considerations needed for present decision making that will have future impact.
Developing a vision for the library
Authors: Fitsimmons Gary 
Published: October 2013

Purpose
– This article's purpose is to show how to develop and maintain a shared vision for library services among a library staff.

Design/methodology/approach
– The article shows what a shared vision is, then how to develop it.

Findings
– The article finds that a sense of ownership in the organization and relationships are keys in building a shared vision.

Practical implications
– A shared vision guides the development and offering of effective library services.

Originality/value
– The value of the article is in learning what goes in to vision building and how to do it.
Mapping values in old vs new members of the European Union
Authors: Capell Ben , Kubra Canhilal S. , Alas Ruth , Sommer Lutz , Ossenkop Carolin 
Published: October 2013

Purpose– The purpose of the paper is twofold. The first purpose is to provide a synthesis of the dominant cross-cultural models and to present the more recent tri-axial model as a promising alternative that responds well to the limitation of prevailing models. Consequently, the second purpose is to employ the model to explore key differences in the culture and values of public service organisations in old and new EU member states.Design/methodology/approach– The paper surveyed public sector employees in four different countries, two old EU (OEU) states (Germany, The Netherlands) and two new EU (NEU) states (Estonia, Lithuania). The employees were asked to classify 60 values on the three axes of the tri-axial model and to select the five most important values in their organization. The survey replies were analyzed and mapped to facilitate comparison of the tri-axial cultural profile of the two EU clusters.Findings– The results show differences in value orientation between the two groups of countries: the public sector in the OEU member states appears to be more ethically and less pragmatically oriented than in the NEU member states. Findings show that in the new member states, value congruence is very high across demographic groups, in contrast to the situation encountered in the OEU member states.Research limitations/implications– Further research should include more countries before generalising the conclusions of this study to the rest of the OEU and NEU countries. Furthermore, although collecting data from a homogeneous unit (e.g. public sector) suggests more valid comparison, in the future, research should strive to also examine additional units, for example private companies.Practical implications– The conclusions derived from this exploratory cultural mapping provide useful knowledge for improving international collaboration across public sector organizations.Originality/value– This study is the first study that maps the values in the public sector using the tri-axial model.
Mapping the values and culture in Chinese public sectors: an exploratory study
Authors: Liu Ying , Bao Yuanjie , Liu Wei 
Published: October 2013

Purpose– The exploratory study introduced the tri-axial model as a basic framework of cultural value to Chinese public sectors. The study tries to display value mapping of the Chinese public sectors and to examine the relationship between the identified values with organizational outcome variables, which is normally characteristic of an exploratory research. The paper aims to discuss these issues.Design/methodology/approach– 404 civil servants were asked to classify 62 cultural values into three axes, emotional, economical and ethical, and to attain the importance of the 62 values.Findings– Five cultural values including happiness, belonging, harmony, achievement, and efficiency are identified to be the most important values in Chinese public sectors. Harmony and achievement were found to affect organizational outcome variables.Research limitations/implications– Sample size is relatively small, and more cultural differences have been neglected within Chinese culture. And the paper collected data twice and used different means, but analyzed the combined data, which could be problematic.Practical implications– The findings suggest that Chinese civil servants pay much attention on emotional-developmental type of cultural values. Ethic-related culture needs to be emphasized more on culture building behaviors both at the organizational level and at the national level.Originality/value– This is the first time the tri-axial model was introduced into Chinese culture. Testing with Chinese samples, the tri-axial model appears to address some of the important limitations of previous models that were summarized before. The paper successfully grouped all the cultural values into three pre-defined axes. The most important values are identified.
Public sector values: between the real and the ideal
Authors: Gabel-Shemueli Rachel , Capell Ben 
Published: October 2013

Purpose– The purpose of this research is to identify and analyze the core values of the Peruvian public sector in the particular context of recent public management reforms.Design/methodology/approach– After distinguishing between traditional private and public sector values, the paper compared the presence of each of these types of values in two very different sources of data: input from employees' values survey and formal values statements of Peruvian public sector organizations. The analysis includes both a comparison of the presence of traditional public and private sector values in the two sources of data and the identification of the cultural profile of the public sector of Peru using the tri-axial model.Findings– The findings indicate a large gap between values at the theoretical level and values at the practical level. While values statements of public organizations in Peru clearly reflect traditional public sector values, in practice, public sector employees appear to follow a mixture of public and private sector values. Strengthening this conclusion is the finding that the cultural tri-axial profile of the sector is purely economic-pragmatic, which suggests that ethical and emotional values are positioned lower on the values hierarchy.Originality/value– This paper provides the first evidence of two important cultural phenomena in the Peruvian public sector: a broad adoption of private sector values and a gap between the values that are proposed as ethical guidelines (ideal) and the values that are followed in practice (real). The combination of these two phenomena suggests a potential risk to the ethical functioning of the public administration. This risk is especially significant in a developing country like Peru, where many of its poor citizens depend on government support. The paper discusses both the research and practical implications of this study.
Coping with job insecurity
Authors: Richter Anne , Näswall Katharina , De Cuyper Nele , Sverke Magnus , De Witte Hans , Hellgren Johnny 
Published: October 2013

Purpose
– The purpose of the present paper is to investigate how employees' coping (problem, emotion and avoidance focused coping) may affect the reactions to job insecurity. Because the coping investigated in the present study addresses the stressor in different ways, the authors expect different moderating effects depending on the type of coping, which results in three different hypotheses.

Design/methodology/approach
– A sample of 579 Swedish accountants was used to test these hypotheses via surveys.

Findings
– The findings support the authors' assumptions that emotion focused coping weakened the relation of job insecurity and some of the outcomes. Both avoidance and problem focused coping strengthened the relation between job insecurity and some of the outcomes.

Research limitations/implications
– As this study utilizes cross-sectional data and only one occupational group, it is important to test the relations using longitudinal data with different occupational groups in future research.

Practical implications
– From these results some practical conclusions can be drawn as to which coping forms might be more beneficial, which can be helpful for organizations in order to develop intervention programs.

Originality/value
– This study expanded the understanding of coping in the context of job insecurity by testing different forms of coping and including a variety of important outcomes of job insecurity.