bluuebunny/crossref_metadata_2025_split huggingface dataset:
Utility of ZTE MRA in the diagnosis of sigmoid-related VPT
Authors: Shen shanshan , Zhao Zhiguang , Zheng Huifeng , Sun Liqiang , Chen Yingmin 
Published: August 2024

Abstract

Purpose
Patients with vascular pulsatile tinnitus (VPT) originating from the sigmoid sinus are scanned using the ZTE MRA technique. This technique can reveal the transverse sinus-sigmoid sinus system without the need for exogenous contrast agents, and it can assess the diagnostic value of ZTE MRA.
Methods and material:
This study received prior approval and written consent from the Institutional Review Board. We collected 13 patients with sigmoid VPT (2 men, 11 women, aged 40.3 ± 12.0 years, 27–59 years) who underwent CT venography (CTV), MR venography (MRV), and ZTE MRA. The aim was to evaluate the diagnostic accuracy of ZTE MRA in demonstrating the deformed vascular mass, sigmoid sinus diverticulum (SSD), and the degree of transverse sinus stenosis (TSS).
Results
ZTE MRA can show the type of vascular malformation, the location of SSD, and there is no statistical difference in assessing the length and extent of TSS.
Conclusions
ZTE MRA can be used as a supplement and auxiliary means when CTV examination cannot be performed and can provide hemodynamic information of the transverse sinus-sigmoid sinus, which is of guiding significance for studying the pathogenesis of VPT.
Risk factors and prognostic model of carbapenem-resistant Klebsiella pneumoniae in patients with bloodstream infection
Authors: Zeng Ling , Ma Jia-xin , Qiu Jie-hui , Ren Qun , Wei Chunping , Cheng Na 
Published: August 2024

Abstract

Purpose
Infections caused by Carbapenem-resistant Klebsiella pneumoniae (CRKP) are increasing annually, with bloodstream infection (BSI) being a significant outcome associated with CRKP, resulting in higher mortality rates. The objective of this investigation was to explore the risk factors for bloodstream infection with CRKP and the factors linked to poor patient prognosis, and to formulate a forecast model for infection and prognosis.
Methods
758 patients with Klebsiella pneumoniae (KP) bloodstream infections were collected from September 2017 to June 2022. Using SPSS.25 and R 3.6.1 software, we analysed the data to identify the independent influencing factors of CRKP-BSI in hospitalised patients. Based on the identified risk factors, we constructed a prediction model and visualised the results as a column line graph. The predictive model's discrimination was assessed using the Receiver Operating Characteristic (ROC) curve's area under the curve (AUC), while its calibration was assessed through the calibration plot.
Results
Nosocomial infection (OR = 4.257, 95% CI 2.479–7.308), ICU admission (OR = 4.070, 95% CI 2.479–6.682), shock (OR = 2.733, 95% CI 1.488–5.019), APTT (OR = 1.032, 95% CI 1.002–1.063), PTA (OR = 0.984, 95% CI 0.973–0.996), FBG (OR = 1. 301, 95% CI 1.096–1.545), carbapenems (OR = 2.812, 95% CI 1.766–4.479), aminoglycosides (OR = 5.536, 95% CI 2.091–14.654), and beta-lactam (OR = 2.241, 95% CI 1.378–3.621) antibiotic usage had an impact on CRKP bloodstream infections. The model demonstrated an area under the ROC curve of 0.834 in the modelling group, with the calibration curve indicating favourable alignment between the model's predictions and actual observations. The model exhibited significant differentiation in the validation group, with the calibration curve reinforcing its efficacy. The model's efficacy was influenced by admission to ICU (OR = 8.172, 95% CI 4.389–15.216), shock (OR = 3.081, 95% CI 1.836–5.172), and haemodialysis (OR = 3.788, 95% CI 1.337-10.). 738), The study developed a prognostic model for CRKP-BSI patients using blood glucose (OR = 1.133, 95% CI 1.034–1.242) and PTA (OR = 0.977, 95% CI 0.961–0.993). The model's ROC curve had an area of 0.869 and the calibration curve indicated satisfactory predictive accuracy. The external validation group's predictive model ROC curve had an area of 0.826. The calibration curve demonstrated that the predictive and actual value curves of the model corresponded well.
Conclusion
Following the outbreak of CRKP-BSI, healthcare staff must efficiently manage risk factors and recognize high-risk patients with a poor prognosis at the earliest opportunity, and implement suitable interventions to enhance patient prognosis.
Self-esteem and Depressive Symptoms in Diagnosed Psychiatric Patients: A Longitudinal Mediation Model
Authors: Yin Xifan , Li Yifan , Ye Yingying , Wang Yibo , Zha Yichang , Xu Liang , Qin Xiangjie , Wei Shengzhong , Feng Xinyu 
Published: August 2024

Abstract

This study examined the relationship between self-esteem, interpersonal sensitivity, rumination, and depression in patients of MDD or GAD. the Rosenberg Self-Esteem Scale, the Interpersonal Sensitivity subscale of Symptom Checklist-90, the Chinese version of the Rumination Response Scale, and the Patient Health Questionnaire nine-item depression scale (PHQ-9) were used to measure 159 diagnosed adults. The study measured depression, self-esteem and interpersonal sensitivity at T1 and rumination and depression at T2 after a 10–14-day interval. The study found that after controlling for depression at T1, age, gender, and measurement time interval, low self-esteem at T1 could impact on depression at T2 through the mediation of reflection at T2, as well as through the chain mediation of interpersonal sensitivity at T1 and rumination at T2. The results indicated that for patients of MDD or GAD with low self-esteem, we could pay attention to intervening with rumination and interpersonal sensitivity, such as rumination-focused cognitive behavioral therapy or interpersonal psychotherapy.
Per and poly-fluoroalkyl substances and respiratory health in an Inuit community
Authors: Aker Amira , Courtemanche Yohann , Ayotte Pierre , Robert Philippe , Gaudreau Éric , Lemire Mélanie 
Published: August 2024

Abstract

Background
Concentrations of plasma per and poly-fluoroalkyl substances (PFAS) are elevated in the Inuit population of Nunavik and may be causing adverse effects. Respiratory health outcomes have been associated with PFAS, but has not been explored in Inuit communities. The aim of the study was to examine the association between PFAS and respiratory health outcomes, and the moderating role of nutritional biomarkers.
Methods
We included up to 1298 participants of the Qanuilirpitaa? 2017 survey aged 16–80 years. Generalized regression models were used to estimate the associations between six individual PFAS congeners and four self-reported symptoms, four spirometry measures, and physician-diagnosed asthma. Outcomes associated with PFAS from single chemical models were further explored using Bayesian Kernel Machine Regression (BKMR). The modifying effect of n-3 PUFA in red blood cell quartiles and vitamin D deficiency were examined on the associations between PFAS and respiratory outcomes.
Results
PFNA and PFOS were associated with asthma (odds ratio (OR) 1.61, 95% confidence interval (CI) 1.12, 2.32; OR 1.45 95% CI 1.04, 2.03). PFOA, PFNA, PFDA and PFHxS were associated with a decrease in the ratio between the forced expiratory volume in the first second and forced vital capacity (FEV1/FVC). No associations were observed with self-reported respiratory symptoms. No associations were observed between a PFAS mixture and asthma. Some associations were modified by nutritional factors, namely, stronger associations between PFOA and PFHxS and asthma with lower n-3 PUFA levels and stronger associations between PFDA, PFUnDA and PFOS and FEV1/FVC with vitamin D deficiency.
Conclusion
These findings add to the growing literature on the impacts of PFAS on respiratory health, and the importance of their global regulation. Associations were modified by nutritional factors pointing to the nutritional value of traditional Inuit foods.
Activity Identification via Wi-Fi Channel State Information with Neural Networks
Authors: CHARY VALABOJU SHIVA KUMAR , Venkateswarlu Bellamkonda Satya Sai , Vemuri Saketh , Pasupuleti Venkata Naga Sai Suraj , Burra Vijaya Babu , Tumuluru Praveen 
Published: August 2024

Abstract

Leveraging Wi-Fi Channel State Information (CSI) offers a fresh approach to environmental sensing and detecting human activities (HAR). This technique has diverse safety and security applications, utilizing existing Wi-Fi routers instead of privacy-intrusive visual methods. This study presents a comprehensive pipeline for human activity recognition via Wi-Fi CSI, comparing two deep learning techniques. We explore the impact of hardware setups on Wi-Fi CSI signals and enhance data collection by seamlessly integrating real-life scenarios, improving model assessment. We investigate Inception Time and LSTM models for activity recognition. The code and dataset are publicly accessible for transparency and community-driven research advancement.
The heterogeneous characteristics of the microstructure in cement stone under the effect of self-weight segregation
Authors: Wang Zhiheng , Li Xiuhao , Wang Meng , Gong Yu’an , Liu Rentai , Cheng Bingchuan , Bai Jiwen , Zhu Zhijing 
Published: August 2024

Abstract

Under the influence of self-weight segregation, the microstructure of cement stone exhibits significant heterogeneous characteristics, but the mechanisms of these variations have not been revealed. In this study, the pore size distribution and porosity of the cement stone with various water-to-cement (w/c) ratios and the initial height were measured using NMR methods. The relationships between cement stone porosity and height position were fitted using a simplified self-weight consolidation finite model and a small strain model. The results show that under the same w/c ratios, the density and porosity of the stones formed at the bottom of cement grout columns with different initial heights are essentially consistent. The variation trend in the porosity of cement stone with a lower w/c ratio, such as 0.8, aligns with the predictions of the finite strain model. However, as the w/c ratio increases, like 1.0 or 1.2, the reduction in effective stress between particles delays the self-weight consolidation process, enhancing the influence of cement hydration. The skeletal structure formed by the hydration products results in a decrease in consolidation strain, ultimately making the porosity change more consistent with a small strain model. Additionally, XRD patterns and SEM images show that with increasing height position, the amount of ettringite increases while C-S-H decreases, leading to a looser structure of the cement stone and an increase in porosity.
Syk inhibitor attenuates lupus in FcγRIIb-/- mice through the Inhibition of DNA extracellular traps from macrophages and neutrophils via p38MAPK-dependent pathway
Authors: Leelahavanichkul Asada , Sae-khow Kritsananwan , Charoensappakit Awirut , Udompornpitak Kanyarat , Saisorn Wilasinee , Issara-Amphorn Jiraphorn , Palaga Tanapat 
Published: August 2024

Abstract

Spleen tyrosine kinase (Syk), an important hub of immune signaling, is activated by several signalings in active lupus which could be interfered by Syk inhibitor but is still not completely evaluated in innate immune cells associated with lupus activity. Hence, a Syk inhibitor (fostamatinib; R788) was tested in vivo using Fc gamma receptor-deficient (FcγRIIb-/-) lupus mice and in vitro (macrophages and neutrophils). After 4 weeks of oral Syk inhibitor, 40 week-old FcγRIIb-/- mice (a full-blown lupus model) demonstrated less prominent lupus parameters (serum anti-dsDNA, proteinuria, and glomerulonephritis), systemic inflammation, as evaluated by serum TNFa, IL-6, and citrullinated histone H3 (CitH3), gut permeability defect, as indicated by serum FITC dextran assay, serum lipopolysaccharide (LPS), and serum (1→3)-β-D-glucan (BG), extracellular traps (ETs) and immune complex deposition in spleens and kidneys (immunofluorescent staining of CitH3 and immunoglobulin G) than FcγRIIb-/- mice with placebo. Due to the spontaneous elevation of LPS and BG in serum, LPS plus BG (LPS+BG) was used to activate macrophages and neutrophils. After LPS+BG stimulation, FcγRIIb-/- macrophages and neutrophils demonstrated predominant abundance of phosphorylated Syk (Western blotting), and the pro-inflammatory responses (CD86 flow cytometry analysis, supernatant cytokines, ETs immunofluorescent, and flow cytometry-based apoptosis). With RNA sequencing analysis and western blotting, the Syk-p38MAPK-dependent pathway was suggested as downregulating several inflammatory pathways in LPS+BG-activated FcγRIIb-/- macrophages and neutrophils. Although both inhibitors against Syk and p38MAPK attenuated macrophage and neutrophil inflammatory responses against LPS+WGP, the apoptosis inhibition by p38MAPK inhibitor was not observed.
These results suggested that Syk inhibitor (fostamatinib) improved the severity of lupus caused by FcγRIIb defect partly through Syk-p38MAPK anti-inflammation that inhibited both ET formation and cytokine production from innate immune cells.
Association Between Early Sitting and Functional Mobility Recovery After Hip-Fracture Surgery in Old Patients: A Prospective Cohort Study.
Authors: Catalano-Nadakhovskaia Clarissa , Pérez-López Carlos , García-Lerma Esther , Ivanov Laura Alexandra , Macho-Perez Oscar , Rodríguez-Molinero Alejandro 
Published: August 2024

Abstract

Background
Hip fractures significantly impact elderly individuals, leading to compromised mobility and various adverse outcomes. The importance of early post-surgery mobilization in regaining pre-fracture levels of mobility is recognized, but lacks standardized definitions and implementation strategies. This study aimed to assess the impact of early sitting position 24 hours after hip-fracture surgery on functional mobility recovery after 30 days using data from the Spanish National Hip Fracture Registry (RNFC).
Methods
Prospective cohort study, including patients aged ≥ 74 years admitted for hip-fracture surgery between 2017 and 2020 at Sant Camil Residential Hospital. Data from the RNFC were analyzed, and linear regression models were developed to assess the association between early sitting after surgery (ESAS) and mobility recovery at 30 days after surgery.
Results
Of 486 identified patients, 321 were included, with an estimated ESAS prevalence of 38.32% (95% CI: 32.97–43.88). ESAS was significantly associated with improved mobility recovery at 30 days. Multivariate regression models consistently revealed ESAS as a modest independent predictor of better post-surgery mobility. Factors such as age, cognitive capacity, and general health also impacted mobility recovery.
Conclusion
The ESAS effect, while modest, emerges as a significant predictor of hip mobility recovery among elderly patients with hip fractures 30 days after surgery. These findings underscore the potential of this low-risk, low-cost intervention in enhancing functional mobility recovery strategies and emphasize the need for further research to uncover its broader implications in post-operative care. Implementation of early sitting could be enhanced, as only a third of patients in our study underwent this simple intervention.
Professional competency and moral courage among staff nurses
Authors: Ali Eman Hassan Mohamed , Khalifa Marwa Abdelrahman Gaber 
Published: August 2024

Abstract

Background: Nurses must possess professional competency and moral courage to ensure the excellence of care and safety for customers, communicate effectively with other healthcare staff, and promote the establishment of consistent and universal care.
Aim: This study aimed to investigate the relationship between professional competency and moral courage among staff nurses.
Methods: A descriptive correlational study design was conducted with 172 staff nurses. The researchers used structured equation modeling.
Results: This study revealed that more than three-fifths of the studied subjects reported a moderate level of professional competency (followed by a low level), and two-thirds of the studied subjects reported a moderate level of moral courage, followed by a low level).
Conclusion: This study concluded that the professional competency of staff nurses was positively correlated and significantly correlated with moral courage among nurses (r =.637**, p =0.000).
Trial Registration Number [TRN] The study protocol was approved by the Research Ethics Committee of the Faculty of Nursing, Ain Shams University (code number: NUR 24.2.129).
Risk of Estrogen-Driven Malignancies in Females on 5-alpha Reductase Inhibitors
Authors: Rohan Thomas , Turchetta Grace , Yang Sherry 
Published: August 2024

Abstract

Importance:
It is hypothesized that 5α-reductase inhibitors (5aRI) increase aromatase-mediated conversion of testosterone to estrogen, which may facilitate development of estrogen-driven malignancy. Previous studies in male patients receiving 5aRI treatment failed to demonstrate an increased risk of breast cancer; however, similar data in females are lacking.
Methods
We utilized the TriNetX Global Collaborative Network, which provides access to electronic medical records from ~ 145 million patients. Both cohorts included females with an ICD-10 diagnosis of androgenetic alopecia (AGA), non-scarring hair loss, or cicatricial alopecia and excluded patients with prior diagnoses of estrogen-driven malignancies. The study cohort included patients with at least 6 months of finasteride of dutasteride use, while the control cohort excluded any-time use of these medications. A 1:1 matched propensity score analysis was performed for confounding risk factors.
Results
After matching, there were 5,156 patients in each cohort (median age 57.8 ± 14.3). Ten years after first medication use, patients taking 5aRI had a 27.6% decreased risk of having a breast cancer diagnosis compared to controls (95% CI: 0.532–0.985, p = 0.0389). The study cohort had a 31.9% decrease in lifetime breast cancer risk compared to the control patients (95% CI: 0.503–0.923; p = 0.0126). Between the 5aRI and control groups, there was no significant difference in risk of developing ovarian or endometrial cancer (95% CI: 0.317–1.605; p = 0.4126 and 95% CI; 0.025–1.13; p = 0.09367 respectively).
Conclusions
The data show that there is no increased risk of estrogen-driven malignancies for women taking 5aRI for alopecia, and that 5aRI use may be protective against breast cancer.
Construction Of High Energy Density and Long Cycle Life Zinc-ion Hybrid Capacitors Based on Wedelia Chinensis-Derived Biomass Porous Carbon
Authors: Liu Miaomiao , Wan Shenteng , Wang Letong , Pang Zengwei , Yao Tong , niu xiaohui , Wang Kunjie , Li Hongxia 
Published: August 2024

Abstract

Zinc ion hybrid capacitors (ZIHCs) have received much attention due to their low cost, safety and green features. However, its development is seriously restricted by defects such as low energy density and insufficient cycle life. The selection of suitable capacitive materials can effectively enhance their electrochemical performance. Porous carbon materials become the choice of capacitive materials for ZIHCs due to their high ion adsorption capacity and fast kinetic behavior. In this paper, an oxygen-enriched biomass-derived nanoporous carbon was prepared by pyrolysis of Wedelia chinensis combing the chemical activation. The oxygen-rich functional groups on the surface of this nanoporous carbon can provide additional pseudocapacitance and improve the wettability of the material. The excellent electrochemical performance of the material in aqueous electrolyte was verified by assembling symmetrical capacitors (SCs) and ZIHCs devices. Specifically, as high as 151 W h kg− 1 of energy density and 18 kW kg− 1 of power output as well as 25000 cycles of long cycle life with 97.4% of capacity retention were demonstrated by as-assembled ZIHC.
The Effects of Acute Kidney Injury on COVID-19 related Clinical Outcomes and Mortality in a Hispanic Population
Authors: Khalafi Seyed , Helmsdoerfer Kristen , Evans Justin , Lumbreras Tyson , Tiula Kira , Dwivedi Alok Kumar , Dihowm Fatma 
Published: August 2024

Abstract

The effect of coronavirus disease (COVID)-19 has been severe in minority communities across the United States, especially in Hispanics. Acute kidney injury (AKI) is observed as a significant factor to worsening outcomes in patients with COVID-19. In this retrospective observational study, clinical outcomes related to renal impairment were assessed among Hispanic patients with COVID-19 by screening all patients hospitalized between March, 2020 and March, 2021 at a tertiary care hospital in El Paso, Texas, resulting in a total of 1,478 patients. The cohort consisted of 385 (26%) with renal impairment, including 195 (13.2%) AKI, 128 (8.7%) chronic kidney disease, and 60 (4.0%) end stage renal disease. Patients with any form of renal impairment with COVID-19 had an increased mortality risk. AKI yielded increased mortality and ICU transfer than other forms of renal impairment. Mitigation strategies and proactively monitoring of renal impairment patients with COVID-19 need to be implemented in Hispanics.
Association of sleep problems with suicidal behaviors and healthcare utilization in adults with chronic diseases: the role of mental illness
Authors: Wen Chen , Wei Zheng , Chalghaf Nasr , Woldegerima Woldegebriel Assefa , Wu Jianhong , Bragazzi Nicola Luigi , Garbarino Sergio 
Published: August 2024

Abstract

Objectives: This study aimed to examine the association between sleep problems and suicidal behaviors and healthcare utilization in Canadian adults with chronic diseases, and the mediating role of mental illness.
Methods: Data were drawn from the Canadian Community Health Survey, 2015-16, from Ontario, Manitoba, and Saskatchewan– the provinces that selected the survey module on sleep. A total of 22,700 participants aged ≥18 years () and diagnosed with chronic diseases were enrolled in the study. Sleep problems referred to extreme sleep durations (either <5 or ≥10 hours) and insomnia. Mental illness was defined as a self-reported mood or anxiety disorder.
Results: Of the 6,318,400 participants, higher prevalence of all suicidal behaviors and healthcare utilization outcomes were found in participants with extreme sleep durations (compared with 7 to <8 hours), and in participants with insomnia (compared with no insomnia). After multivariate adjustment, extreme sleep durations and insomnia were still independently associated with increased odds of suicidal behaviors and healthcare utilization. Mediation analyzes showed that mental illness partly mediated the associations of extreme sleep durations and insomnia with suicidal behaviors and healthcare utilization.
Conclusions:
In conclusion, both extreme sleep durations and insomnia were associated with increased odds of suicidal behaviors and healthcare utilization outcomes in adults with chronic diseases, whereas mental illness partially mediated the association.