bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hybrid modeling for quality by design and PAT‐benefits and challenges of applications in biopharmaceutical industry
Authors: von Stosch Moritz , Davy Steven , Francois Kjell , Galvanauskas Vytautas , Hamelink Jan‐Martijn , Luebbert Andreas , Mayer Martin , Oliveira Rui , O'Kennedy Ronan , Rice Paul , Glassey Jarka 
Published: May 2014

AbstractThis report highlights the drivers, challenges, and enablers of the hybrid modeling applications in biopharmaceutical industry. It is a summary of an expert panel discussion of European academics and industrialists with relevant scientific and engineering backgrounds. Hybrid modeling is viewed in its broader sense, namely as the integration of different knowledge sources in form of parametric and nonparametric models into a hybrid semi‐parametric model, for instance the integration of fundamental and data‐driven models. A brief description of the current state‐of‐the‐art and industrial uptake of the methodology is provided. The report concludes with a number of recommendations to facilitate further developments and a wider industrial application of this modeling approach. These recommendations are limited to further exploiting the benefits of this methodology within process analytical technology (PAT) applications in biopharmaceutical industry.
Characterization of oxygen transfer in vertical microbubble columns for aerobic biotechnological processes
Authors: Peterat Gena , Schmolke Hannah , Lorenz Thomas , Llobera Andreu , Rasch Detlev , Al‐Halhouli Ala'aldeen T. , Dietzel Andreas , Büttgenbach Stephanus , Klages Claus‐Peter , Krull Rainer 
Published: May 2014

ABSTRACTThis paper presents the applicability of a microtechnologically fabricated microbubble column as a screening tool for submerged aerobic cultivation. Bubbles in the range of a few hundred micrometers in diameter were generated at the bottom of an upright‐positioned microdevice. The rising bubbles induced the circulation of the liquid and thus enhanced mixing by reducing the diffusion distances and preventing cells from sedimentation. Two differently sized nozzles (21 × 40 µm2 and 53 × 40 µm2 in cross‐section) were tested. The gas flow rates were adjustable, and the resulting bubble sizes and gas holdups were investigated by image analysis. The microdevice features sensor elements for the real‐time online monitoring of optical density and dissolved oxygen. The active aeration of the microdevice allowed for a flexible oxygen supply with mass transfer rates of up to 0.14 s−1. Slightly higher oxygen mass transfer rates and a better degassing were found for the microbubble column equipped with the smaller nozzle. To validate the applicability of the microbubble column for aerobic submerged cultivation processes, batch cultivations of the model organism Saccharomyces cerevisiae were performed, and the specific growth rate, oxygen uptake rate, and yield coefficient were investigated. Biotechnol. Bioeng. 2014;111: 1809–1819. © 2014 Wiley Periodicals, Inc.
Comparative pharmacokinetic study of two boswellic acids in normal and arthritic rat plasma after oral administration of Boswellia serrata extract or Huo Luo Xiao Ling Dan by LC‐MS
Authors: Wang Hui , Zhang Chenning , Wu Yun , Ai Yu , Lee David Y.‐W. , Dai Ronghua 
Published: May 2014

ABSTRACTHuo Luo Xiao Ling Dan (HLXLD), a Chinese herbal formula composed of 11 different herbs, has been used traditionally for the treatment of arthritis and other chronic inflammatory diseases. However, the pharmacokinetic profile of its anti‐inflammatory bioactive compounds has not been elucidated. Boswellic acids are the bioactive compounds with potent anti‐inflammatory activity isolated from Boswellia serrate which is one of the 11 herbs of HLXLD. The objective of the study was to compare the pharmacokinetics of the two bioactive bowsellic acids: 11‐keto‐β‐boswellic acid and 3‐O‐acetyl‐11‐keto‐β‐boswellic following oral administration of HLXLD or Boswellia serrata extract alone in normal and arthritic rats. An LC‐MS method was developed and validated for the determination of 11‐keto‐β‐boswellic acid and 3‐O‐acetyl‐11‐keto‐β‐boswellic in the comparative pharmacokinetic study. The results showed that there were significant differences in pharmacokinetic parameters between normal and arthritic groups. Interestingly, the absorptions of two boswellic acids were significantly higher in HLXLD than Boswellia serrata extract alone, indicating the synergistic effect of other herbal ingredients in HLXLD. This comparative pharmacokinetic study provided direct evidence supporting the notion that the efficacy of a complex mixture such as HLXLD is better than that of single components in treating human diseases. Copyright © 2014 John Wiley & Sons, Ltd.
Rapid identification of glycerophospholipids from RAW264.7 cells by UPLC/ESI ‐QTOF‐MS
Authors: She Yuqi , Song Jianao , Yang E. , Zhao Lili , Zhong Yanmei , Rui Wen , Feng Yifan , Wu Xia 
Published: May 2014

ABSTRACTThe study aims to develop a rapid, sensitive ultra‐performance liquid chromatography coupled with an electrospray ionization quadruple time‐of‐flight tandem mass spectrometry (UPLC/Q‐TOF‐MS) analytical method for identifying glycerophospholipids (GPLs) from RAW264.7 cells. A total of 78 GPLs including 22 phosphatidylethanolamines (PEs), 49 phosphatidylcholines (PCs), four phosphatidylglycerols, one phosphatidylinositol and two unknown GPLs were identified. PC (14:0/16:1), PC (14:0/16:0), PE (0:0/20:3), PE (22:5/0:0) and PE (22:3/0:0) were identified for the first time. The UPLC/Q‐TOF‐MS method is suitable for targeting analysis of GPLs from RAW264.7 cells, which allows us to find out new GPLs compositions related to inflammatory diseases and to explain their pharmacological roles in inflammatory process. Copyright © 2014 John Wiley & Sons, Ltd.
p62/SQSTM1 is involved in caspase‐8 associated cell death induced by proteasome inhibitor MG132 in U87MG cells
Authors: Zeng Rui‐xia , Zhang Yi‐Bo , Fan Yu , Wu Ge‐Li 
Published: May 2014

AbstractGlioblastoma multiforme (GBM) is the most common and lethal type of brain cancer. Proteasome inhibitors are emerging as a new class of anti‐glioma agents; however, the mechanisms of their killing malignant cells are still unclear. We treated U87MG cells with the proteasome inhibitor MG132 and found that cell death correlated with caspase‐8 activation and autophagy protein p62/SQSTM1.To explore the role of autophagy and p62/SQSTM1 in MG132‐induced cancer cell death, we measured the alteration of MG132's cytotoxicity by autophagy inhibition, autophagy induction or variation of p62/SQSTM1 gene expression. Autophagy was activated upon MG132 treatment for short periods, while inhibition of autophagy aggravated MG132‐induced cell death followed by high levels of p62/SQSTM1 and active caspase‐8 (p18). Moreover, U87MG cell death was dependent on p62/SQSTM1, and its function required its C‐terminus UBA domain to attenuate the MG132‐induced cell death. The results suggest that p62/SQSTM1 is a potential contributor in determining the fate of U87MG cells deficient in proteolytic activity.
Effect of Poly(vinyl pyrrolidone) on Antifouling Properties of Asymmetric Poly(ethylene‐co‐vinyl alcohol) Membranes
Authors: Riyasudheen Nechikkattu , Paul Manu Jose , Sujith Athiyanathil 
Published: May 2014

AbstractPoly(ethylene‐co‐vinyl alcohol)/poly(vinyl pyrrolidone) (EVAL/PVP) blend membranes with antifouling properties were prepared by nonsolvent induced phase separation. Residual PVP in the sample was calculated by infrared spectroscopic data and confirmed by thermogravimetric analysis. The effect of residual PVP on hydrophilicity and permeation characteristics of the membranes was evaluated. Porosity and equilibrium water content of the membranes were influenced by the addition of PVP. The effect of protein fouling on flux using bovine serum albumin as a model system was studied in detail. The residual PVP content could enhance the antifouling property of the membrane. All membranes proved to have sufficient mechanical strength to withstand pressure‐driven filtrations.
Characterization of CeO2 Promoter of a Nanocrystalline Ni/MgO Catalyst in Dry Reforming of Methane
Authors: Khajenoori Masoud , Rezaei Mehran , Meshkani Fereshteh 
Published: May 2014

AbstractCeria‐promoted nickel catalysts supported on nanocrystalline MgO were prepared and employed in methane reforming with CO2. Their characterization was accomplished by X‐ray diffraction, BET, temperature‐programmed oxidation, and temperature‐programmed reduction (TPR) techniques. Cerium oxide (CeO2) proved to have a positive effect on catalytic activity, stability, and carbon suppression in methane reforming with CO2. A higher CeO2 content increased the catalyst activity and decreased the amount of deposited carbon over the spent catalysts. The suppression of carbon was related to the high oxygen storage capacity of CeO2. In addition, TPR analysis revealed that the CeO2 promoter reduced the chemical interaction between nickel and support, resulting in an increase in reducibility and higher dispersion of nickel.
Coprecipitated Ni‐Co Bimetallic Nanocatalysts for Methane Dry Reforming
Authors: Mirzaei Fateme , Rezaei Mehran , Meshkani Fereshsteh 
Published: May 2014

AbstractMethane dry reforming was studied over nanostructure bimetallic Ni‐Co‐MgO catalysts. The catalysts were prepared by coprecipitation with different Ni‐Co contents and characterized by XRD, BET, N2 adsorption/desorption, temperature‐programmed reduction (TPR), SEM, and temperature‐programmed oxidation (TPO) techniques. XRD results let conclude that all samples contained MgO crystallite phases. With a higher Ni content the intensity of the diffraction peaks became stronger, indicating growth of the crystallite size of the prepared solid solutions. BET analysis demonstrated that a higher Ni‐Co content decreased the surface area. The optimal catalyst could be determined which had the highest activity and a good stability in dry reforming reaction.
Intrinsic and Effective Kinetics of Cobalt‐Catalyzed Fischer‐Tropsch Synthesis in View of a Power‐to‐Liquid Process Based on Renewable Energy
Authors: Kaiser Philipp , Pöhlmann Ferdinand , Jess Andreas 
Published: May 2014

AbstractThe production of liquid hydrocarbons based on CO2 and renewable H2 is a multi‐step process consisting of water electrolysis, reverse water‐gas shift, and Fischer‐Tropsch synthesis (FTS). The syngas will then also contain CO2 and probably sometimes H2O, too. Therefore, the kinetics of FTS on a commercial cobalt catalyst was studied with syngas containing CO, CO2, H2, and H2O. The intrinsic kinetic parameters as well as the influence of pore diffusion (technical particles) were determined. CO2 and H2O showed only negligible or minor influence on the reaction rate. The intrinsic kinetic parameters of the rate of CO consumption were evaluated using a Langmuir‐Hinshelwood (LH) approach. The effectiveness factor describing diffusion limitations was calculated by two different Thiele moduli. The first one was derived by a simplified pseudo first‐order approach, the second one by the LH approach. Only the latter, more complex model is in good agreement with the experimental results.
Ultrafine Dust Filtration Using Precoat Materials Considering the Influence of Filter Media
Authors: Schiller Sascha , Schmid Hans‐Joachim 
Published: May 2014

AbstractUltrafine dust separation from different sources like industry, traffic, or private households has become increasingly important in the last decade. A compact baghouse filter system has been developed which is suitable for pellet heaters. For filtration, a precoat material is required to prevent clogging of the filter media by the ultrafine dust particles. In order to ensure the best performance of this filter system, different combinations of filter media and precoat materials, e.g., grade efficiencies and the cake area load for the various filter media, were investigated in a special test rig. With this highly efficient technology, extremely high separation efficiencies of > 99 % and ultrafine dust concentrations of > 1 mg cm−3 could be reached in a long‐term stable process.
Parallel Operation of Centrifugal Pumps: Effects of Rotational Speed Differences due to Motor Slip
Authors: Koegler Andreas F. , Evert Amrei , Alt Nicolas S. A. , Schluecker Eberhard 
Published: May 2014

AbstractIn industrial plants, centrifugal pumps are frequently operated in parallel configuration, not least for redundancy and operational reliability reasons. However, regarding the resulting pressure pulsations and energy consumption, this operation mode has so far not been in the focus of scientific studies. The object of the present article is to clarify the effect of parallel operation with respect to the observable pressure pulsations. Measurements were carried out with two identical centrifugal pumps operating in parallel mode in an industrial‐scale closed‐loop piping system. The results suggest that, regarding both the resulting pressure pulsations and the operating point of each pump, this operation mode is quite sensitive to smallest rotational speed deviations as they may occur due to different motor slip. The results indicate furthermore that, for minimum pressure pulsations, equal power consumptions of the two pumps are crucial, but not necessarily equal rotational speeds.
ChemInform Abstract: Sr4Ru6ClO18, a New Ru4+/5+ Oxy‐Chloride, Solved by Precession Electron Diffraction: Electric and Magnetic Behavior.
Authors: Roussel Pascal , Palatinus Lukas , Belva Frederic , Daviero‐Minaud Sylvie , Mentre Olivier , Huve Marielle 
Published: May 2014

AbstractCrystals of the title compound are hydrothermally synthesized in supercritical water from mixtures of Sr(OH)2, RuO2, and KClO3 (autoclave, 2000 bar, 600 °C, 24 h).
ChemInform Abstract: Syntheses, Structures, and Electronic Properties of Ba3FeUS6 and Ba3AgUS6.
Authors: Mesbah Adel , Malliakas Christos D. , Lebegue Sebastien , Sarjeant Amy A. , Stojko Wojciech , Koscielski Lukasz A. , Ibers James A. 
Published: May 2014

AbstractBa3FeUS6 (I) and Ba3AgUS6 (II) are prepared by reactions of BaS, U, S, M (Fe or Ag), and Sb2S3 as flux (evacuated silica tubes, 1223 K, 8 d).
ChemInform Abstract: Structural Study of Ca2Gd2Ge2O9 and Optical Spectroscopy of the Eu3+ Dopant Ion.
Authors: Piccinelli Fabio , Pedroni Marco , Cagliero Stefano , Speghini Adolfo , Bettinelli Marco 
Published: May 2014

AbstractCrystalline samples of Ca2Gd2Ge2O9 and the Eu3+‐doped compound Ca2Gd1.98Eu0.02Ge2O9 are prepared by solid state reaction of CaCO3, GeO2, and Gd2O3 and Eu2O3 (1450 °C, three times 3 h).
ChemInform Abstract: Nanoporous BiVO4 Photoanodes with Dual‐Layer Oxygen Evolution Catalysts for Solar Water Splitting.
Authors: Kim T. W. , Choi K.‐S. 
Published: May 2014

AbstractA high‐surface‐area, nanoporous BiVO4 electrode composed of particles smaller than its hole diffusion length can effectively increase the electron‐hole separation yield without additional doping.
ChemInform Abstract: Rapid Synthesis of Novel Flowerlike K0.46Mn2O4(H2O)1.4 Hierarchical Architectures and Their Catalytic Degradation of Formaldehyde in Aqueous Solution.
Authors: Ahmed Khalid Abdelazez Mohamed , Huang Kaixun 
Published: May 2014

AbstractNanostructured microflower‐like birnessite type Mn oxide hierarchical architectures are hydrothermally synthesized from KMnO4 and NaF as a reductant in H2SO4 at low temperature (autoclave, 120 °C, 150 min).
ChemInform Abstract: Rare‐Earth Transition‐Metal Chalcogenides Ln3MGaS7 (Ln: Nd, Sm, Dy, Er; M: Co, Ni) and Ln3MGaSe7 (Ln: Nd, Sm, Gd, Dy, M: Co; Ln: Nd, Gd, Dy, M: Ni).
Authors: Yin Wenlong , Shi Youguo , Kang Bin , Deng Jianguo , Yao Jiyong , Wu Yicheng 
Published: May 2014

AbstractThe new title compounds are prepared by solid state reactions of Co, Ni, Ga2S3 or Ga2Se3, Ln, and S or Se (1323 or 1373 K, 48 h) and characterized by single crystal XRD and magnetic measurements.
ChemInform Abstract: A Novel Dumbbell‐Like Polyoxometalate Assembled of Copper(II)‐Disubstituted Monovacant Keggin Polyoxoanions with a Tetranuclear Copper Cluster.
Authors: Miao Hao , Xu Xiao , Ju Wei‐Wei , Wan Hong‐Xiang , Zhang Yu , Zhu Dun‐Ru , Xu Yan 
Published: May 2014

AbstractThe dimeric [Cu(bipy)(μ2‐OH)]4 [(H2O) (bipy)2HPW11Cu2O39] 2·2EtOH·10H2O Keggin polyoxometalate is prepared by solvothermal reaction of Cu(NO3)2, H3PW12O40, and bipy in H2O/EtOH (2:1) solution (pH 4.6 adjusted with H3PO3, autoclave, 150 °C, 3 d; 38% yield).
ChemInform Abstract: Chiral‐at‐Metal Octahedral Iridium Catalyst for the Asymmetric Construction of an All‐Carbon Quaternary Stereocenter.
Authors: Chen Liang‐An , Tang Xiaojuan , Xi Jianwei , Xu Weici , Gong Lei , Meggers Eric 
Published: May 2014

AbstractAn iridium complex that draws its chirality exclusively from an Ir‐centered octahedral stereocenter is described as highly efficient catalyst for the asymmetric Michael addition of indoles to nitroacrylic esters to give products with quaternary stereocenters with excellent stereoselectivity.
ChemInform Abstract: Oxygen‐Involved Oxidative Deacetylation of α‐Substituted β‐Acetyl Amides — Synthesis of α‐Keto Amides.
Authors: Li Dianjun , Yu Wei 
Published: May 2014

AbstractThe oxidizing system of tBuOOH and catalytic amounts of CuCl2 is investigated with or without the presence of oxygen atmosphere.
ChemInform Abstract: Free Radical‐Mediated Chemoselective Reduction of Enones.
Authors: Sultan Aeysha , Raza Abdul Rauf , Tahir Muhammad Nawaz 
Published: May 2014

Abstract1,4‐Reduction of variously substituted α,β‐unsaturated cyclic and acyclic enones is achieved using Bu3SnH and catalytic amounts of AIBN.
ChemInform Abstract: Organocatalytic Enantioselective Synthesis of 2,3‐Allenoates by Intermolecular Addition of Nitroalkanes to Activated Enynes.
Authors: Qian Hui , Yu Xiuzhao , Zhang Junliang , Sun Jianwei 
Published: May 2014

AbstractThis is the first efficient intermolecular addition of nitroalkanes to activated enynes affording the title compounds under mild conditions.
ChemInform Abstract: Chelation‐Controlled Additions to α‐Silyloxy Aldehydes: An Autocatalytic Approach.
Authors: Raffier Ludovic , Stanton Gretchen R. , Walsh Patrick J. 
Published: May 2014

AbstractThe Lewis‐acid diethyl zinc chloride, which is responsible for promoting chelation, is generated in situ in an autocatalytic fashion.
ChemInform Abstract: Syntheses of Aldol Products and Cyanohydrins from Carboxylic Acids Using Hydrosilanes, Organosilicon Reagents, and Indium Triiodide Catalyst.
Authors: Inamoto Yoshihiro , Nishimoto Yoshihiro , Yasuda Makoto , Baba Akio 
Published: May 2014

AbstractThe indium triiodide‐catalyzed transformation of carboxylic acids to β‐hydroxy esters and cyanohydrins of type (XVII) is described.
ChemInform Abstract: Hydrogen Bond Organocatalysis of Benzotriazole in Transamidation of Carboxamides with Amines.
Authors: Nguyen Thanh Binh , Al‐Mourabit Ali , Ermolenko Ludmila , Tran Huu Dau Marie‐Elise 
Published: May 2014

AbstractBenzotriazole is used as an efficient catalyst for transamidation reactions of amides, imides, and urea.
ChemInform Abstract: Regio‐ and Stereocontrol in the Michael‐Initiated Ring‐Closure Reactions of γ,δ‐Epoxy‐α,β‐unsaturated Esters, Ketones, Sulfones, and Amides.
Authors: Dhakal Ramesh C. , Dieter R. Karl 
Published: May 2014

AbstractThe title reaction results in the formation of trisubstituted cyclopropanes mainly with high diastereoselectivity.
ChemInform Abstract: N‐Heterocyclic Carbene Catalyzed Reaction of Cinnamils Leading to the Formation of 2,3,8‐Triaryl Vinyl Fulvenes: An Uncommon Transformation.
Authors: Sinu C. R. , Suresh Eringathodi , Nair Vijay 
Published: May 2014

AbstractUnder optimized conditions the uncommon cascade reaction gives vinyl fulvenes and ortho‐terphenyl derivatives as by‐products.
ChemInform Abstract: Palladium‐Catalyzed Coupling of Alkynes with Unactivated Alkenes in Ionic Liquids: A Regio‐ and Stereoselective Synthesis of Functionalized 1,6‐Dienes and Their Analogues.
Authors: Li Jianxiao , Yang Shaorong , Jiang Huanfeng , Wu Wanqing , Zhao Jinwu 
Published: May 2014

AbstractThe new method provides a practical, efficient, and versatile method for the synthesis of functionalized 1,6‐dienes and higher analogues in good yields.
ChemInform Abstract: Pd‐Catalyzed Asymmetric Conjugate Addition of Arylboronic Acids to 2‐Nitroacrylates: A Facile Route to β2‐Homophenylglycines.
Authors: Petri Andreas , Seidelmann Oliver , Eilitz Uwe , Lessmann Frank , Reissmann Stefan , Wendisch Volkmar , Gutnov Andrey 
Published: May 2014

AbstractThis method yields products (V) which are potential precursors of β2‐homophenylglycines.
ChemInform Abstract: Solvent Effects in Gold‐Catalyzed A3‐Coupling Reactions.
Authors: Price Gregory A. , Brisdon Alan K. , Flower Kevin R. , Pritchard Robin G. , Quayle Peter 
Published: May 2014

AbstractA dimethylbenzylamine gold complex is found to be an effective catalyst for the three‐component coupling reactions of aldehydes, terminal alkynes, and amines.
ChemInform Abstract: Ni‐Catalyzed Stereoselective Arylation of Inert C—O Bonds at Low Temperatures.
Authors: Cornella Josep , Martin Ruben 
Published: May 2014

AbstractThe Ni‐catalyzed direct C‐O arylation of 2,3‐dihydrofurans with Grignard reagents proceeds with high chemo‐ and E/Z‐selectivity to produce Z‐configured homoallylic alcohols.
ChemInform Abstract: Improvement of the Friedel—Crafts Benzoylation by Using Bismuth Trifluoromethanesulfonate in 1‐Butyl‐3‐methylimidazolium Trifluoromethanesulfonate Ionic Liquid under Microwave Irradiation.
Authors: Tran Phuong Hoang , Do Ngoc Bich Le , Le Thach Ngoc 
Published: May 2014

AbstractThe title method allows the benzoylation of activated arenes and naphthalene in short reaction times.
ChemInform Abstract: Iron Porphyrin‐Catalyzed Three‐Component Reaction of Ethyl Diazoacetate with Aliphatic Amines and β,γ‐Unsaturated α‐Keto Esters.
Authors: Ma Chaoqun , Xing Dong , Zhai Changwei , Che Jiuwei , Liu Shunying , Wang Jue , Hu Wenhao 
Published: May 2014

AbstractThe structure of the product (IVd) is confirmed by X‐ray analysis.
ChemInform Abstract: Co‐Immobilization of an Enzyme and a Metal into the Compartments of Mesoporous Silica for Cooperative Tandem Catalysis: An Artificial Metalloenzyme.
Authors: Engstroem Karin , Johnston Eric V. , Verho Oscar , Gustafson Karl P. J. , Shakeri Mozaffar , Tai Cheuk‐Wai , Baeckvall Jan‐E. 
Published: May 2014

AbstractA hybrid catalyst consisting of Pd(0) nanoparticles and Candida antarctica lipase B (CALB) co‐immobilized on a glutaraldehyde‐modified amino‐functionalized siliceous mesocellular foam is developed and used as catalyst for the highly efficient dynamic kinetic resolution of phenethylamine.
ChemInform Abstract: Vanadium‐Catalyzed Oxidative Strecker Reaction: α‐C—H Cyanation of para‐Methoxyphenyl (PMP)‐Protected Primary Amines.
Authors: Zhu Chen , Xia Ji‐Bao , Chen Chuo 
Published: May 2014

AbstractThe title method allows a direct access to one‐carbon extended α‐aminonitriles via oxidation of amines and subsequent cyanation of the resulting imine intermediate with trimethylsilyl cyanide.
ChemInform Abstract: Lewis Base‐Catalyzed Reactions of Cyclopropenones: Novel Synthesis of Mono‐ or Multi‐Substituted Allenic Esters.
Authors: Yang Yuan‐Liang , Zhang Zhen , Zhang Xiao‐Nan , Wang De , Wei Yin , Shi Min 
Published: May 2014

AbstractThis method yields allenes from cyclopropenones via ring‐opening.
ChemInform Abstract: Stereoselective Heck Reactions with Vinyl Sulfoxides, Sulfides and Sulfones.
Authors: Bachmann Daniel G. , Wittwer Christopher C. , Gillingham Dennis G. 
Published: May 2014

AbstractThe use of Pd[P(tBu)3]2 as the catalyst with Et3N as the base allows efficient Heck arylation of a variety of aryl bromides with vinyl sulfoxides, vinyl sulfides, and vinyl sulfones with generally good yield and E‐selectivity.
ChemInform Abstract: Isoxazol‐3‐yl(isothiazol‐3‐yl)‐1,2,4‐triazoles, ‐tetrazoles, and ‐1,3,4‐oxadiazoles: Synthesis, Palladium Complexes, and Catalytic Applications.
Authors: Bumagin N. A. , Petkevich S. K. , Kletskov A. V. , Livantsov M. V. , Golantsov N. E. , Potkin V. I. 
Published: May 2014

AbstractA variety of the title bis‐heterocycles [cf.