bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Reactions of 5‐Substituted 1,3,4‐Thiadiazole‐2‐thiones with Chloroacetylenephosphonates.
Authors: Egorov Dmitrij M. , Piterskaya Yulija L. , Dogadina Albina V. , Svintsitskaya Nataly I. 
Published: July 2015

AbstractThe nucleophilic addition of thiadiazole‐ 2‐thiones to chloroacetylene‐2‐phosphonates proceeds regio‐ and chemoselectively to afford novel, fused, phosphorus‐containing thiazolo[2,3‐b][1,3,4]thiadiazol‐4‐ylium chlorides in high yields.
ChemInform Abstract: Catalyst‐Free P—C Coupling Reactions of Halobenzoic Acids and Secondary Phosphine Oxides under Microwave Irradiation in Water.
Authors: Jablonkai Erzsebet , Keglevich Gyoergy 
Published: July 2015

AbstractThe synthesis of phosphinoylbenzoic esters is achieved through sequential P—C‐coupling and esterification of halobenzoic acids.
ChemInform Abstract: Pd‐Catalyzed P‐Arylation of Triarylantimony Dicarboxylates with Dialkyl H‐Phosphites without a Base: Synthesis of Arylphosphonates.
Authors: Matsumura Mio , Dong Yuqiang , Kakusawa Naoki , Yasuike Shuji 
Published: July 2015

AbstractThe first example of a carbon‐phosphorus bond formation by using an organoantimony compound as a pseudo‐halide is given.
ChemInform Abstract: A Highly Efficient and Reusable MCM‐41‐Immobilized Bipyridine Copper(I) Catalyst for the C—Se Coupling of Organoboronic Acids with Diaryl Diselenides.
Authors: Zhao Hong , Jiang Yuanyuan , Chen Qiurong , Cai Mingzhong 
Published: July 2015

AbstractA variety of selenides is obtained by cross‐coupling reaction of organoboronic acids with diaryl diselenides.
ChemInform Abstract: Copper Catalyzed Oxidative Coupling Reactions for Trifluoromethylselenolations — Synthesis of R‐SeCF3 Compounds Using Air Stable Tetramethylammonium Trifluoromethylselenate.
Authors: Lefebvre Quentin , Pluta Roman , Rueping Magnus 
Published: July 2015

AbstractThe presented approach allows the late‐stage functionalization of complex organic molecules.
ChemInform Abstract: Sesquiterpenoids Isolated from an Endophyte Fungus Diaporthe sp.
Authors: Chen Chao‐Jun , Liu Xian‐Xian , Zhang Wen‐Jing , Zang Le‐Yun , Wang Gang , Ng Seik Weng , Tan Ren‐Xiang , Ge Hui‐Ming 
Published: July 2015

AbstractTen new sesquiterpenoids including six brasilane‐type sesquiterpenoids, diaporols J‐O [cf.
ChemInform Abstract: New Sesquiterpenoids Isolated from Atractylodes lancea Fermented by Marine Fungus.
Authors: Kamauchi Hitoshi , Kinoshita Kaoru , Takatori Kazuhiko , Sugita Takashi , Takahashi Kunio , Koyama Kiyotaka 
Published: July 2015

AbstractFrom the fermented rhizomes of A.
ChemInform Abstract: Vegetable‐Based Dye‐Sensitized Solar Cells
Authors: Calogero Giuseppe , Bartolotta Antonino , Di Marco Gaetano , Di Carlo Aldo , Bonaccorso Francesco 
Published: July 2015

AbstractReview: overview of vegetable pigments in dye‐sensitized solar cells, starting from main limitations of cell performance to cost analysis and scaling‐up prospects; 669 refs.
Insight into CaMgSi2O6:Eu2+,Mn2+,Dy3+ Nanoprobes: Influence of Chemical Composition and Crystallinity on Persistent Red Luminescence
Authors: Rosticher Céline , Viana Bruno , Laurent Guillaume , Le Griel Patrick , Chanéac Corinne 
Published: July 2015

AbstractOptical imaging in which photons are the information source seems to be a very important technique, less expensive and less harmful than more conventional diagnostic methods and suitable, for instance, for sensitive diagnosis capable of detecting cancer at an early stage. We have recently developed inorganic persistent luminescent nanoparticles (PLNPs) as nanoprobes useful for in vivo imaging that can master the difficulties of the biological environment such as tissue autofluorescence, absorption, or photobleaching because they are excited before injection into the animal. In this work, we have focused on silicate materials, CaMgSi2O6, that emit in the red/near‐infrared range for several hours. With the aim of improving their luminescent properties and nanoparticle size, we have explored a new method of synthesis that allows a suitable yield of particles and studied the influence of chemical composition and crystalline structure on luminescence intensity. Adjusting the molar ratio of Ca/Mg/Si and crystallization temperature, very fine nanoparticles of PLNPs have been obtained with an improved luminescence and the high production yield necessary to promote the emergence of these nanoprobes in the field of optical imaging.
Constraints and potentials for the nutritional modulation of the fatty acid composition of ruminant meat
Authors: Bessa Rui J. B. , Alves Susana P. , Santos‐Silva José 
Published: July 2015

The meat from ruminants can be a valuable dietary source of rumenic acid (c9,t11‐CLA) and of n‐3 long chain polyunsaturated fatty acids (n‐3 LC‐PUFA). Nevertheless, commonly ruminant meats present a fairly low content of both c9,t11‐CLA and n‐3 LC‐PUFA. Most of c9,t11‐CLA in meat is derived from the delta‐9 desaturation of t11‐18:1 catalyzed by stearoyl‐CoA desaturase (SCD) and deposited in triacylglycerides (TAG). Thus, optimizing c9,t11‐CLA in meat implies: a high substrate supply, a high SCD activity, and a high intramuscular fat (IMF) deposition. High rumen t11‐18:1 outflow requires high forage diets which down‐regulate SCD activity and IMF deposition. Conversely, as most animals are finished with cereal rich concentrate diets, the SCD activity and IMF deposition are promoted but the rumen outflow of t11‐18:1 frequently is replaced by t10‐18:1 (t10‐shift) which cannot be converted to CLA. Thus the occurrence of the rumen t10‐shift is probably the main constraint to c9,t11‐CLA enrichment in meat, as is reviewed in detail. The constrains to n‐3 LC‐PUFA enrichment of ruminant meat are mostly associated to the extensive rumen biohydrogenation of PUFA, the low elongation and desaturation of 18:3n‐3 into n‐3 LC‐PUFA, and the capacity of muscle lipids to incorporate n‐3 LC‐PUFA. Considering the almost exclusive esterification of n‐3 LC‐PUFA in membrane phospholipids, the limits to n‐3 LC‐PUFA incorporation in muscle are discussed considering the amount of and type of available phospholipids as well as the possibility of its esterification in TAG.Simplified summary of the main drives that could limit the c9,t11‐CLA deposition in meat of ruminants fed high forage or high concentrate diets.
Synthesis of Annulated Anthracenes, Carb­azoles, and Thiophenes Involving Bradsher‐Type Cyclodehydration or Cycli­zation–Reductive‐Dehydration Reactions
Authors: Rafiq Settu Muhamad , Sivasakthikumaran Ramakrishnan , Karunakaran Jayachandran , Mohanakrishnan Arasambattu K. 
Published: July 2015

AbstractA conventional BF3·OEt2‐mediated Bradsher‐type cyclodehydration of 2‐arylmethyl benzaldehydes in CH2Cl2 at room temperature gave polycyclic aromatic and heteroaromatic compounds. Alternatively, these compounds could be synthesized in better yields from 2‐arylmethylbenzoic acids by triflic‐acid‐mediated cyclization followed by reductive dehydration.
Preparation, X‐ray Structure, and Reactivity of Triisopropylsilyl‐Substituted Aryl­iodonium Salts
Authors: Yusubov Mekhman S. , Svitich Dmitrii Yu. , Yoshimura Akira , Kastern Brent J. , Nemykin Victor N. , Zhdankin Viktor V. 
Published: July 2015

Abstract(4‐Triisopropylsilylphenyl)phenyliodonium tosylate, an aryliodonium salt bearing an extremely bulky, electron‐donating triisopropylsilyl (TIPS) substituent in the phenyl ring, was prepared by the reaction of (4‐tributyltinphenyl)triisopropylsilane with [hydroxy(tosyloxy)iodo]benzene (Koser's reagent). The TIPS‐substituted aryliodonium tosylate was further converted into (4‐triisopropylsilylphenyl)phenyliodonium bromide, the structure of which was established by single‐crystal X‐ray diffraction. Reactions of the TIPS‐substituted arylodonium tosylate with bromide, azide, and thiocyanate anions predominantly afforded products of nucleophilic substitution in the electron‐rich aromatic ring bearing the TIPS substituent. This unusual result is explained by the steric effect of the extraordinary bulky para‐TIPS substituent on the configuration of the reaction intermediate.
Advanced frame element for seismic analysis of masonry structures: model formulation and validation
Authors: Raka Eva , Spacone Enrico , Sepe Vincenzo , Camata Guido 
Published: July 2015

SummaryThis paper presents a masonry panel model for the nonlinear static and dynamic analysis of masonry buildings suitable for the seismic assessment of new and existing structures. The model is based on an equivalent frame idealization of the structure and stems from previous research on force‐based frame elements. The element formulation considers axial, bending, and shear deformations within the framework of the Timoshenko beam theory. A phenomenological cyclic section law that accounts for the shear panel response is coupled, through equilibrium between shear and bending forces along the element, with a fiber‐section model that accounts for the axial and bending responses. The proposed panel model traces with a low computational burden and numerical stability the main aspects of the structural behavior of masonry panels and is suitable for analyses of multi‐floor buildings with a relatively regular distribution of openings and with walls and floors organized to grant a box‐like behavior under seismic loads. The model capabilities are validated though analyses of simple unreinforced masonry panels and comparisons with published experimental results. The model accuracy is strongly dependent on the fiber and shear constitutive laws used. However, the formulation is general, and laws different from those employed in this study are easily introduced without affecting the model formulation. Copyright © 2015 John Wiley & Sons, Ltd.
Approach Bias Modification in Food Craving—A Proof‐of‐Concept Study
Authors: Brockmeyer Timo , Hahn Carolyn , Reetz Christina , Schmidt Ulrike , Friederich Hans‐Christoph 
Published: July 2015

AbstractThe aim of the present proof‐of‐concept study was to test a novel cognitive bias modification (CBM) programme in an analogue sample of people with subclinical bulimic eating disorder (ED) psychopathology. Thirty participants with high levels of trait food craving were trained to make avoidance movements in response to visual food stimuli in an implicit learning paradigm. The intervention comprised ten 15‐minute sessions over a 5‐week course. At baseline, participants showed approach and attentional biases towards high‐caloric palatable food that were both significantly reduced and turned into avoidance biases after the training. Participants also reported pronounced reductions in both trait and cue‐elicited food craving and in ED symptoms as well. The overall evaluation of the training by the participants was positive. The specific CBM programme tested in this pilot trial promises to be an effective and feasible way to alter automatic action tendencies towards food in people suffering from bulimic ED psychopathology. Copyright © 2015 John Wiley & Sons, Ltd and Eating Disorders Association.
Central Coherence, Visuoconstruction and Visual Memory in Patients with Eating Disorders as Measured by Different Scoring Methods of the Rey Complex Figure Test
Authors: Weider Siri , Indredavik Marit Sæbø , Lydersen Stian , Hestad Knut 
Published: July 2015

AbstractObjectiveThe aims of this study were to examine the performance of eating disorder (ED) patients on the Rey Complex Figure Test and to investigate the validity of the Q‐score as a new method for measuring central coherence (CC).MethodForty‐one patients with anorexia nervosa, 40 patients with bulimia nervosa and 40 healthy controls completed the Rey Complex Figure Test, which was scored both quantitatively and qualitatively.ResultsBoth ED groups scored lower than the healthy controls on copy, recall and the Q‐score. For the anorexia nervosa group, performance on the Central Coherence Index was associated with the nadir body mass index. Performance on the recall measures was independently associated with the nadir body mass index and depressive symptoms for the bulimia nervosa group. There was a strong correlation between the Q‐score and the Central Coherence Index (r = 0.77).DiscussionThe study reveals different levels of CC and suggests that the Q‐score might be an applicable method for measuring CC in ED patients. Copyright © 2015 John Wiley & Sons, Ltd and Eating Disorders Association.
Social Rank, Rank‐Related Life Events and Eating Pathology
Authors: Troop Nicholas A. 
Published: July 2015

AbstractBackgroundThis study explored the role of meaning in the link between stress and disordered eating, in particular focusing on social rank.MethodTwo hundred and eleven women completed measures of eating pathology, depression, social comparison and life events where life events were assessed in terms of general loss, threat, shame and loss of social status.ResultsEvents involving loss of social status were related to eating pathology but only in women reporting self‐perceived low rank. Events that did not concern social status were unrelated to eating pathology.DiscussionWomen who perceive themselves to be low social status appear vulnerable to events that concern their social status. Copyright © 2015 John Wiley & Sons, Ltd and Eating Disorders Association.
Connectivity‐based segmentation of the periaqueductal gray matter in human with brainstem optimized diffusion MRI
Authors: Ezra Martyn , Faull Olivia Kate , Jbabdi Saad , Pattinson Kyle Thomas 
Published: July 2015

AbstractThe periaqueductal gray matter (PAG) is a midbrain structure, involved in key homeostatic neurobiological functions, such as pain modulation and cardiorespiratory control. Animal research has identified four subdivisional columns that differ in both connectivity and function. Until now these findings have not been replicated in humans. This study used high‐resolution brainstem optimized diffusion magnetic resonance imaging and probabilistic tractography to segment the human PAG into four subdivisions, based on voxel connectivity profiles. We identified four distinct subdivisions demonstrating high spatial concordance with the columns of the animal model. The resolution of these subdivisions for individual subjects permitted detailed examination of their structural connectivity without the requirement of an a priori starting location. Interestingly patterns of forebrain connectivity appear to be different to those found in nonhuman studies, whereas midbrain and hindbrain connectivity appears to be maintained. Although there are similarities in the columnar structure of the PAG subdivisions between humans and nonhuman animals, there appears to be different patterns of cortical connectivity. This suggests that the functional organization of the PAG may be different between species, and as a consequence, functional studies in nonhumans may not be directly translatable to humans. This highlights the need for focused functional studies in humans. Hum Brain Mapp 36:3459–3471, 2015. © 2015 The Authors Human Brain Mapping Published by Wiley Periodicals, Inc.
A topographical organization for action representation in the human brain
Authors: Handjaras Giacomo , Bernardi Giulio , Benuzzi Francesca , Nichelli Paolo F. , Pietrini Pietro , Ricciardi Emiliano 
Published: July 2015

AbstractHow the human brain represents distinct motor features into a unique finalized action still remains undefined. Previous models proposed the distinct features of a motor act to be hierarchically organized in separated, but functionally interconnected, cortical areas. Here, we hypothesized that distinct patterns across a wide expanse of cortex may actually subserve a topographically organized coding of different categories of actions that represents, at a higher cognitive level and independently from the distinct motor features, the action and its final aim as a whole. Using functional magnetic resonance imaging and pattern classification approaches on the neural responses of 14 right‐handed individuals passively watching short movies of hand‐performed tool‐mediated, transitive, and meaningful intransitive actions, we were able to discriminate with a high accuracy and characterize the category‐specific response patterns. Actions are distinctively coded in distributed and overlapping neural responses within an action‐selective network, comprising frontal, parietal, lateral occipital and ventrotemporal regions. This functional organization, that we named action topography, subserves a higher‐level and more abstract representation of finalized actions and has the capacity to provide unique representations for multiple categories of actions. Hum Brain Mapp 36:3832–3844, 2015. © 2015 The Authors Human Brain Mapping Published by Wiley Periodicals, Inc.
Hippocampal sharp wave‐ripple: A cognitive biomarker for episodic memory and planning
Authors: Buzsáki György 
Published: July 2015

ABSTRACTSharp wave ripples (SPW‐Rs) represent the most synchronous population pattern in the mammalian brain. Their excitatory output affects a wide area of the cortex and several subcortical nuclei. SPW‐Rs occur during “off‐line” states of the brain, associated with consummatory behaviors and non‐REM sleep, and are influenced by numerous neurotransmitters and neuromodulators. They arise from the excitatory recurrent system of the CA3 region and the SPW‐induced excitation brings about a fast network oscillation (ripple) in CA1. The spike content of SPW‐Rs is temporally and spatially coordinated by a consortium of interneurons to replay fragments of waking neuronal sequences in a compressed format. SPW‐Rs assist in transferring this compressed hippocampal representation to distributed circuits to support memory consolidation; selective disruption of SPW‐Rs interferes with memory. Recently acquired and pre‐existing information are combined during SPW‐R replay to influence decisions, plan actions and, potentially, allow for creative thoughts. In addition to the widely studied contribution to memory, SPW‐Rs may also affect endocrine function via activation of hypothalamic circuits. Alteration of the physiological mechanisms supporting SPW‐Rs leads to their pathological conversion, “p‐ripples,” which are a marker of epileptogenic tissue and can be observed in rodent models of schizophrenia and Alzheimer's Disease. Mechanisms for SPW‐R genesis and function are discussed in this review. © 2015 The Authors Hippocampus Published by Wiley Periodicals, Inc.
Localization of bone morphogenetic protein 13 in human intervertebral disc and its molecular and functional effects in vitro in 3D culture
Authors: Gulati Twishi , Chung Sylvia A. , Wei Ai‐qun , Diwan Ashish D. 
Published: July 2015

ABSTRACTOur laboratory has demonstrated that bone morphogenetic protein 13 prevented the effects of annular injury in an ovine model, maintaining intervertebral disc height, cell numbers and increasing extracellular matrix production compared to degenerated controls. The present study sought to examine the molecular effects of bone morphogenetic protein 13 on human degenerated disc cells and localize its expression in both human degenerate and scoliotic disc tissue. Effect of bone morphogenetic protein 13 on human derived nucleus pulposus, annulus fibrosus and endplate cells cultured in alginate beads was evaluated by changes in proteoglycan and collagen content. Migratory potential of disc cells towards bone morphogenetic protein 13 was also examined. Bone morphogenetic protein 13 induced significant proteoglycan accumulation in nucleus (18%), annulus (21%) and endplate (23%) cells cultured in alginate beads (p < 0.05) compared to controls. Further bone morphogenetic protein 13 increased collagen I and II protein expression in nucleus and endplate cells. Nucleus cells displayed a significant chemotactic response towards bone morphogenetic protein 13. The endogenous expression of bone morphogenetic protein 13 in degenerate disc tissue was not different to scoliotic disc. Bone morphogenetic protein 13 has the potential to enhance extracellular matrix accumulation and induce cell migration in certain disc cells. © 2015 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 33:1769–1775, 2015.
MRI evaluation of spontaneous intervertebral disc degeneration in the alpaca cervical spine
Authors: Stolworthy Dean K. , Bowden Anton E. , Roeder Beverly L. , Robinson Todd F. , Holland Jacob G. , Christensen S. Loyd , Beatty Amanda M. , Bridgewater Laura C. , Eggett Dennis L. , Wendel John D. , Stieger‐Vanegas Susanne M. , Taylor Meredith D. 
Published: July 2015

ABSTRACTAnimal models have historically provided an appropriate benchmark for understanding human pathology, treatment, and healing, but few animals are known to naturally develop intervertebral disc degeneration. The study of degenerative disc disease and its treatment would greatly benefit from a more comprehensive, and comparable animal model. Alpacas have recently been presented as a potential large animal model of intervertebral disc degeneration due to similarities in spinal posture, disc size, biomechanical flexibility, and natural disc pathology. This research further investigated alpacas by determining the prevalence of intervertebral disc degeneration among an aging alpaca population. Twenty healthy female alpacas comprised two age subgroups (5 young: 2–6 years; and 15 older: 10+ years) and were rated according to the Pfirrmann‐grade for degeneration of the cervical intervertebral discs. Incidence rates of degeneration showed strong correlations with age and spinal level: younger alpacas were nearly immune to developing disc degeneration, and in older animals, disc degeneration had an increased incidence rate and severity at lower cervical levels. Advanced disc degeneration was present in at least one of the cervical intervertebral discs of 47% of the older alpacas, and it was most common at the two lowest cervical intervertebral discs. The prevalence of intervertebral disc degeneration encourages further investigation and application of the lower cervical spine of alpacas and similar camelids as a large animal model of intervertebral disc degeneration. © 2015 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 33:1776–1783, 2015.
Single intra‐articular dexamethasone injection immediately post‐surgery in a rabbit model mitigates early inflammatory responses and post‐traumatic osteoarthritis‐like alterations
Authors: Heard Bryan J. , Barton Kristen I. , Chung May , Achari Yamini , Shrive Nigel G. , Frank Cyril B. , Hart David A. 
Published: July 2015

ABSTRACTDespite surgical reconstruction of the anterior cruciate ligament, a significant number of patients will still develop post‐traumatic osteoarthritis (PTOA). Our objective was to determine if mitigating aspects of the acute phase of inflammation following a defined knee surgery with a single administration of a glucocorticoid could prevent the development of PTOA‐like changes within an established rabbit model of surgically induced PTOA. An early and late post‐surgical time‐point was investigated in this study (48 h and 9 weeks post‐surgery) in which the following groups were repeated (each n = 6, for a total of 24 rabbits per time‐point, and 48 rabbits used in the study): control (age/sex matched), sham (arthrotomy), drill injury (arthrotomy + two drill holes to a non‐cartilaginous area of the femoral notch), and drill injury + single intra‐articular (IA) injection of dexamethasone (DEX). At 48 h post‐surgery, DEX treatment significantly lowered the mRNA levels for a subset of pro‐inflammatory mediators, and significantly lowered the histological grade. Nine weeks post surgery, DEX treatment significantly lowered the histological scores (presented as effect size) for synovium (3.8), lateral femoral condyle (3.9), and lateral tibial cartilage (5.1) samples. Thus, DEX likely acts to prevent injury induced inflammation that could contribute to subsequent joint damage. © 2015 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 33:1826–1834, 2015.