bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tangeretin alleviates inflammation and oxidative response induced by spinal cord injury by activating the Sesn2/Keap1/Nrf2 pathway
Authors: Peng Birong , Hu Jinwei , Sun Yuanfang , Huang Yating , Peng Qingshan , Zhao Weiwen , Xu Wenning , Zhu Lixin 
Published: July 2024

AbstractSpinal cord injury (SCI) is a severe disabling disease that is characterized by inflammation and oxidative reactions. Tangeretin has been shown to possess significant antioxidant and anti‐inflammatory activities. The Keap1/Nrf2 pathway, downstream of the Sesn2 gene, is involved in regulating the inflammation and oxidative response. The main objective of this study was to investigate the effect of tangeretin on SCI and its possible mechanism through cell and animal models. A T9 clamp injury was used for the mouse model and the LPS‐induced stimulation of BV‐2 cells was used for the cell model. The improvement of motor function after SCI was assessed by open field, swimming, and footprint experiments. The morphological characteristics of mouse spinal cord tissue and the levels of INOS, Sesn2, TNF‐α, Keap1, Nrf2, IL‐10, and reactive oxygen species (ROS) in vivo and in vitro were measured by several methods including western blotting, qPCR, immunofluorescence, HE, and Nissl staining. In vivo data showed that tangeretin can improve motor function recovery and reduce neuron loss and injury size in mice with SCI. Simultaneously, the in vitro findings suggested that treatment of BV‐2 cells with tangeretin after LPS stimulation reduced the production of inflammatory factors and ROS, and could convert BV‐2 cells from the M1 to the M2 type. Furthermore, Sesn2 knockout suppressed Keap1/Nrf2, inflammatory factors, ROS levels, and the M1 to M2 transition. Tangeretin can alleviate the inflammation and oxidative response induced by SCI by activating the Sesn2/Keap1/Nrf2 pathway.
Active Biopackaging Films Enriched With Andız (Juniperus drupacea L.) Shell Extract for Fresh Meat Packaging
Authors: Konuk Takma Dilara , Çin Semiha , Şahin Nadeem Hilal 
Published: July 2024

ABSTRACTAndız (Juniperus drupacea L.) shell, a valuable waste produced during the production of andız molasses, was used as a natural source of bioactive compounds. The functional properties of andız shell's extract were determined under various extraction conditions including temperature, time, solid ratio and solvent type. Alginate and gelatin were selected as carbohydrate and protein‐based sources for the development of biodegradable packaging. The optimum film formulation was determined by evaluating physical properties such as thickness, tensile strength, elongation, water vapour permeability, water activity, water solubility and optical properties. In addition to the physical properties, the functional properties such as antioxidant and antimicrobial activity of biocomposite films incorporating extracts in different proportions were also evaluated. Furthermore, the potential usage of this packaging to maintain the quality of fresh meat was investigated during a 12‐day refrigerated storage at 4 °C. Periodic analyses were conducted on the samples for total aerobic mesophilic bacteria count, psychrotrophic bacteria counts, pH, colour and texture properties. The results demonstrated that the meat packaged with active films exhibited a reduction in microbial growth and maintained the quality of meat samples during storage. Therefore, the developed biodegradable active packaging material shows promising functionality for preserving fresh meat and meat products.
Development of Chitosan/Mg−Zn−HAP/ZrO2 Bilayer Coating on Ti Alloy for Biomedical Applications
Authors: Suganthi Sanjeevamuthu , Avula Balakrishna , R Vinaykumar , Rai Rajakumar S. , Gunamalai Lavanya , Hasan Imran , Kumaravel Sakthivel , Durai Mathivanan , Oh Tae Hwan , Surya Chinnasamy 
Published: July 2024

AbstractTitanium alloys (Ti−6Al−4V) are being used in many biomedical applications due to their unique properties of bioactivity, excellent mechanical properties, low toxicity, biocompatibility, and long‐term implant application for their satisfactory corrosion resistance. We have developed a new two‐step fabrication process of zirconium oxide (ZrO2) and Chitosan/Mg−Zn−HAP (Chitosan/M−HAP) bilayer layer coating on Ti alloy for biomedical applications. Flower‐structured bilayers were coated by the electrochemical deposition method. Electrochemically deposited bilayer‐coated Ti alloy specimens were characterized by various analytical techniques like field‐emission scanning electron microscope (FE‐SEM), X‐ray diffraction (XRD), and EDS mapping analysis. Furthermore, the developed bilayer (Chitosan/Mg−Zn−HAP/ZrO2) coated Ti alloy samples improved mechanical properties such as adhesion strength (20.1±0.4 MPa) and hardness (446±4 Hv), compared to other coatings. An investigation of polarization curves showed a positive shift in the polarization values (Ecorr, and Icorr) of the Chitosan/M−HAP/ZrO2 bilayer coatings on Ti alloy. Bilayer‐modified Ti alloy samples show good antimicrobial response toward Gram‐negative and Gram‐positive bacteria. Meanwhile, the cell viability and proliferation of the bilayer‐coated samples were evaluated and the exhibited result improved cell proliferation, and bioactivity compared to other coated materials. From the results, it can be evident that the developed Chitosan/Mg−Zn−HAP/ZrO2 bilayer‐coated Ti alloy could be a good potential candidate for biomedical applications.
Highly Recyclable and Versatile La0.5Nd0.2Ca0.3MnO3 and La0.5Nd0.2Ca0.25K0.05MnO3 Perovskite Catalysts for Effective Removal of Organic Contaminants
Authors: Singh Sumit , Sharma Narayan Dutt , Verma Mukesh Kumar , Singh Rajinder , Singh Devinder 
Published: July 2024

AbstractWastewater contamination, particularly from dye effluents containing organic colorants originating from industrial sources, represents a significant environmental and public health hazard. This study is dedicated to removal of these abundant coloured effluents in wastewater, addressing the imperative need for effective remediation strategies to safeguard ecosystems and human well‐being. In this regard, bare and K‐doped perovskite manganites La0.5Nd0.2Ca0.3MnO3 (LCM) and La0.5Nd0.2Ca0.25K0.05MnO3 (LCKM) nanoparticles respectively were synthesized in order to study their catalytic behaviour for degradation of coloured effluents. The Rietveld analysis applied to the X‐ray diffraction data provides confirmation of orthorhombic symmetry. For exploring the catalytic properties, rhodamine‐B (RhB) dye was chosen as model dye pollutant. The achieved degradation efficiency is substantial, reaching 99 % within a brief period of 10–12 min. Following these results, we have also carried out the degradation of some other dyes such as methylene blue (MB) and methyl orange (MO). It was observed that MO dye was more efficiently degraded in quick time as compared to all the other dyes due to its anionic nature. Furthermore, the comparative catalytic efficiencies of LCM and LCKM catalysts were explained on the basis of Mn3+/Mn4+ redox pairs and it was observed that LCKM had shown better degradation efficiency than LCM.
Mononuclear Aluminum Complexes as Precursors for Cyanosilylation of Carbonyl Compounds
Authors: Ajitrao Kisan Devadkar , Sharma Jyoti , Paul Ishita , Karmakar Himadri , Jain Archana , Panda Tarun K. 
Published: July 2024

AbstractThe synthesis, structural characterization, and catalytic application of two novel aluminum complexes, [κ3ENSe−{Ph2P(E)N−C6H4−SePh}AlMe2] [E=S (1) and Se (2)] supported by new pincer‐type phenylselenium‐phosphanamidinate chalcogenide ligands are described. The molecular structures of both complexes in their solid states reveal a distorted trigonal bipyramidal geometry around the Al(III) ion, involving monoanionic ligand {Ph2P(E)N−C6H4−SePh}− bonded to the AlMe2‐motif in a tridentate manner. Complex 1 was found to be an effective pre‐catalyst for the cyanosilyation of aldehydes and ketones with TMSCN under solvent‐free conditions. The reaction protocol is simple, efficient, and has a diverse substrate scope of aldehydes and ketones, showing superior functional group tolerance. The kinetic study revealed that ketone reduction proceeded with first‐order dependence on ketone concentrations, TMSCN, and catalyst 1.
Enhanced Sensitivity in Photovoltaic 2D MoS2/Te Heterojunction VOC Sensors
Authors: Mohammadzadeh Mohammad Reza , Hasani Amirhossein , Hussain Tanveer , Ghanbari Hamidreza , Fawzy Mirette , Abnavi Amin , Ahmadi Ribwar , Kabir Fahmid , De Silva Thushani , Rajapakse R. K. N. D. , Adachi Michael M. 
Published: July 2024

AbstractVolatile organic compound (VOC) sensors have a broad range of applications including healthcare monitoring, product quality control, and air quality management. However, many such applications are demanding, requiring sensors with high sensitivity and selectivity. 2D materials are extensively used in many VOC sensing devices due to their large surface‐to‐volume ratio and fascinating electronic properties. These properties, along with their exceptional flexibility, low power consumption, room‐temperature operation, chemical functionalization potential, and defect engineering capabilities, make 2D materials ideal for high‐performance VOC sensing. Here, a 2D MoS2/Te heterojunction is reported that significantly improves the VOC detection compared to MoS2 and Te sensors on their own. Density functional theory (DFT) analysis shows that the MoS2/Te heterojunction significantly enhances the adsorption energy and therefore sensing sensitivity of the sensor. The sensor response, which denotes the percentage change in the sensor's conductance upon VOC exposure, is further enhanced under photo‐illumination and zero‐bias conditions to values up to ≈7000% when exposed to butanone. The MoS2/Te heterojunction is therefore a promising device architecture for portable and wearable sensing applications.
A Multimodal Perception‐Enabled Flexible Memristor with Combined Sensing‐Storage‐Memory Functions for Enhanced Artificial Injury Recognition
Authors: Yang Chuan , Wang Hongyan , Zhou Guangdong , Zhao Hongbin , Hou Wentao , Zhu Shouhui , Zhao Yong , Sun Bai 
Published: July 2024

AbstractWith the continuous advancement of wearable technology and advanced medical monitoring, there is an increasing demand for electronic devices that can adapt to complex environments and have high perceptual sensitivity. Here, a novel artificial injury perception device based on an Ag/HfOx/ITO/PET flexible memristor is designed to address the limitations of current technologies in multimodal perception and environmental adaptability. The memristor exhibits excellent resistive switching (RS) performance and mechanical flexibility under different bending angles (BAs), temperatures, humid environment, and repetitive folding conditions. Further, the device demonstrates the multimodal perception and conversion capabilities toward voltage, mechanical, and thermal stimuli through current response tests under different conditions, enabling not only the simulation of artificial injury perception but also holds promise for monitoring and controlling the movement of robotic arms. Moreover, the logical operation capability of the memristor‐based reconfigurable logic (MRL) gates is also demonstrated, proving the device has great potential applications with sensing, storage, and memory functions. Overall, this study not only provides a direction for the development of the next‐generation flexible multimodal sensors, but also has significant implications for technological advancements in many fields such as robotic arms, electronic skin (e‐skin), and medical monitoring.
Breaking silence: A critical duoethnography on examining epistemic violence in negotiating the journey as international graduate students in U.S. higher education
Authors: Mohebali Milad , Jangjou Elmira 
Published: July 2024

AbstractThis critical duoethnography takes silence in classroom discussions as a sociocultural artifact that reveals the norms of the society that upholds it. In this research, we made visible and explored the content of silence we experienced as international graduate students. We found that repeated patterns of silence in classroom discussions acted to silence us as knowers. Moreover, this silencing power of classroom silences was entangled with various factors like immigration status and financial constraints. Finally, by elaborating on ways that we navigated these challenges, we offer implications for research, practice, and policy for improving the experiences of international graduate students in the United States.
Evaluation of acrylonitrile rubber containing zinc oxide as safety products
Authors: El Nashar Doaa E. , Tawfik Soheir Y. , Helaly Fahima M. , Khalaf Aman I. , Soliman Abdelmohsen M. 
Published: July 2024

AbstractThe goal of this research is to find the ideal formulation with the best antimicrobial performance in terms of rheological, physicomechanical, and lowest toxic properties to produce safety rubber for the children toy's and other industrial products. In order to accomplish this, a number of formulations containing ZnO as activator for vulcanization process as well as an antimicrobial agent at concentrations ranging from 1.5 to 40 phr in the presence of 40 phr of different fillers were prepared. The rheological characteristics of prepared compounded rubber samples were assessed and the cure rate was calculated. The overall rheological test results indicate a raise in minimum and maximum torque along with a fall in scorch and optimum cure time. The compounded NBR was vulcanized as estimated curing time. The results illustrated that the NBR vulcanizates containing various amounts of ZnO and 40 phr talc have the best physicomechanical properties. Also, the scanning electron micrographs indicated surface homogeneity and good dispersion of the NBR components. The cytotoxicity test of the investigated vulcanizates on normal retina cell line gave no cytotoxic effect which assessed their safety. These findings offer useful information for antimicrobial NBR vulcanizates for kid's toys and other safety products.Highlights
Synthesis of antimicrobial NBR rubber vulcanizates for safety applications.
The antimicrobial agent used was ZnO.
ZnO nanoparticles and other ingredients were incorporated with NBR on the ordinary rubber mixer.
Rheological, physicomechanical properties and antimicrobial activity of NBR rubber were tested.
The products have better mechanical and antimicrobial safety properties.
Evaluation of Engineering Models for Large‐Scale Cluster Wakes With the Help of In Situ Airborne Measurements
Authors: zum Berge Kjell , Centurelli Gabriele , Dörenkämper Martin , Bange Jens , Platis Andreas 
Published: July 2024

ABSTRACTThe planned expansion of wind energy in the German Bight is creating much more densely staggered wind farms and wind farm clusters. This results in a significantly greater influence of the generated wakes on energy production of neighboring wind farms. The Dornier‐128 research aircraft operated by the Technische Universität of Braunschweig was used to measure the wind field in the lee of single and multiple wind farm clusters in the German Bight on 4 days during July 2020 and July 2021. The data at 120 m aMSL (above mean sea level) were analyzed to identify wake areas and the wind speed decrease behind the wind farm clusters. The observations were then compared to a range of numerical data including the mesoscale model Weather Research and Forecasting (WRF) applying a wind farm parameterization (WRF with wind farm parameterization [WRF‐WF]) to model wake effects and an engineering model with different setups. A model calibrated on a single wind farm is established as the baseline. A modification with a lower wake recovery, the TurbOPark model, and a WRF‐coupled model make up the three additional declinations considered. Overall, the models compared well to the measurement data in the direct vicinity of the wind farms and up to 20–30 km downstream of the wind farm clusters. The accuracy in wind speed prediction of the model results decreased with distance to the wind farms, where the mesoscale model (WRF‐WF) exhibited a more consistent performance across varying distances.
The GGXF Standard File Format for Gridded Geodetic Data
Authors: Crook Chris , Kelly Kevin M. , Lott Roger , Stanaway Richard 
Published: July 2024

AbstractMonitoring the Earth is undertaken in numerous geometric and physical reference frames and coordinate reference systems. Analysis often requires transformation of coordinates between these frames. As the accuracy of positioning and geospatial data improves, the use of gridded data to describe the quantities used in these coordinate transformations is increasing. Rectangular grids also provide an efficient means of disseminating other geodetic data. IAG Commission 1 Working Group 1.3.1 in association with the Open Geospatial Consortium (OGC) have developed a Geodetic data Grid eXchange Format (GGXF) for quantifying and disseminating gridded geodetic data. GGXF was developed in conjunction with a functional model for crustal deformation (FMCD) including support for time-dependent changes, but has been designed to support any type of regularly-gridded geodetic data including but not limited to geoid models, offsets between reference frames (of one, two or three dimensions), velocity grids, tidal surfaces, etc. The purpose of GGXF is to provide a single comprehensive, efficient distribution format through which producers can disseminate gridded geodetic data and users can exchange and apply this information. This paper presents an overview of the GGXF format.
Virtual QCD corrections to gg → ZZ: top-quark loops from a transverse-momentum expansion
Authors: Degrassi Giuseppe , Gröber Ramona , Vitti Marco 
Published: July 2024

Abstract
We present the virtual corrections due to the top-quark loops for the process gg → ZZ at next-to-leading order in QCD. The associated two-loop box diagrams are computed using a small-transverse-momentum expansion. Our results are then merged with those available in the complementary energy region, obtained via a high-energy expansion, in order to provide an analytic result that is valid in the whole phase space. The results presented allow for an efficient modelling of the signal-background interference as well as the irreducible background in off-shell Higgs production.
100 years Nobel Prize for Fritz Pregl: from the introduction of microanalytical methods to today’s developments
Authors: Soukup Rudolf Werner , Theiner Johannes , Kerschbaumer Manfred 
Published: July 2024

AbstractThe award of the Nobel Prize in Chemistry, given in 1923 to Fritz Pregl (1869–1930), a physiologist and chemist from Ljubljana who worked in Graz and Innsbruck, marks a turbulent phase in the development of microchemistry. The paper deals with the prehistory of microchemistry, characterised in part as a qualitative-analytical chemistry carried out on a slide under a microscope. Pregl's aim, though, was quantitative elemental analyses carried out with amounts of less than 2 mg of (organic) material. Pregl influenced many scientific achievements in Austria, especially at the University of Vienna and the TH Vienna. In a radio lecture in 1931, Robert Strebinger, who was involved in the elaboration of microanalytical methods at the TU Vienna, went even so far as to describe microchemistry as an "Austrian science". A breakthrough in the interwar period was the proposal of a special qualitative analysis using spot reactions by Fritz Feigl, winner of the Fritz Pregl-Prize in 1931. The paper is rounded off with selected examples of recent developments in microanalytical methods and of new applications, e.g., in chemistry didactics.
Graphical abstract
Thiophene-based modified graphite electrode for the voltammetric detection of 2-aminoindane in oral fluid
Authors: Pospíšilová Eva , Mazánková Vendula , Otta Jaroslav , Trchová Miroslava , Shishkanova Tatiana V. 
Published: July 2024

AbstractNew psychoactive substances, including 2-aminoindane, pose significant health risks due to their availability and structural similarity to amphetamines. Current detection methods are limited by lengthy analysis times and complex sample preparation. To address this, we present the first voltammetric determination of 2-aminoindane in oral fluid using a graphite electrode modified with a methoxyphenylthiophene-based layer. The electrochemically deposited layer was characterized by scanning electron microscopy, energy-dispersive X-ray spectroscopy, and both infrared and Raman spectroscopies. After the electropolymerization of methoxyphenylthiophene, the electrode was homogeneously covered with shorter oligomers of the substituted polythiophene. Cyclic and square-wave voltammetry were used to gain insight into the interaction between the modified electrode and 2-aminoindane. The modification of the electrode surface enables to record the oxidation of the primary amino group at 0.85 V, with an additional signal assigned to specific interactions being observed at 1.33 V. Determination of a 1.0 × 10–4 M 2-aminoindane concentration in oral fluids was possible, with a recovery ranging from 98 to 100%.
Graphical abstract
Exploring the role of judgement and shared situation awareness when working with AI recommender systems
Authors: Srivastava Divya , Lilly J. Mason , Feigh Karen M. 
Published: July 2024

AbstractAI-advised Decision Making is a form of human-autonomy teaming in which an AI recommender system suggests a solution to a human operator, who is responsible for the final decision. This work seeks to examine the importance of judgement and shared situation awareness between humans and automated agents when interacting together in the form of a recommender systems. We propose manipulating both human judgement and shared situation awareness by providing the human decision maker with relevant information that the automated agent (AI), in the form of a recommender system, uses to generate possible courses of action. This paper presents the results of a two-phase between-subjects study in which participants and a recommender system jointly make a high-stakes decision. We varied the amount of relevant information the participant had, the assessment technique of the proposed solution, and the reliability of the recommender system. Findings indicate that this technique of supporting the human’s judgement and establishing a shared situation awareness is effective in (1) boosting the human decision maker’s situation awareness and task performance, (2) calibrating their trust in AI teammates, and (3) reducing overreliance on an AI partner. Additionally, participants were able to pinpoint the limitations and boundaries of the AI partner’s capabilities. They were able to discern situations where the AI’s recommendations could be trusted versus instances when they should not rely on the AI’s advice. This work proposes and validates a way to provide model-agnostic transparency into recommender systems that can support the human decision maker and lead to improved team performance.