bluuebunny/crossref_metadata_2025_split huggingface dataset:
Venlafaxine as the ‘baby ecstasy’? Literature overview and analysis of web‐based misusers′ experiences
Authors: Francesconi Giulia , Orsolini Laura , Papanti Duccio , Corkery John M. , Schifano Fabrizio 
Published: July 2015

IntroductionVenlafaxine is one of the most frequently prescribed antidepressants worldwide, despite its toxicity risk in overdose. Furthermore, the molecule has been recently identified at the EU‐wide level as one of the novel psychoactive substances. This paper aims at investigating the potential of misuse, taking into account both the existing literature and the analysis of the misusers' experiences as described in venlafaxine misuse web reports.MethodsA literature search was performed using PubMed, Embase, and Medline. Posts/threads relating to venlafaxine misuse issues were identified through Google® and Yahoo® English‐language searches. Resulting websites' data were then qualitatively assessed, and information was collected on a range of issues, including dosage, drug intake modalities, untoward drug effects, and association with other recreational drugs.ResultsA few literature case reports focusing on venlafaxine as a misusing drug were here identified. The molecule was here typically ingested or snorted at dosages up to 10–15 times higher than those clinically advised, obtaining MDMA/amphetamine‐like stimulant and psychedelic effects. Polydrug misuse was commonly reported. Venlafaxine appeared to be widely available online for sale.ConclusionsPhysicians should carefully evaluate patients for history of drug dependence and observe them for signs of venlafaxine misuse. Copyright © 2015 John Wiley & Sons, Ltd.
Enhancing sexual desire and experience: an investigation of the sexual correlates of gamma‐hydroxybutyrate (GHB) use
Authors: Kapitány‐Fövény Máté , Mervó Barbara , Corazza Ornella , Kökönyei Gyöngyi , Farkas Judit , Urbán Róbert , Zacher Gábor , Demetrovics Zsolt 
Published: July 2015

ObjectiveVarious studies have dealt with gamma‐hydroxybutyrate's (GHB) potential role in sexual assaults, while the sexual correlates of intentional recreational GHB use have not well been highlighted. Our study aims to explore GHB's sexual effects, the patterns of choice of sexual partners, the frequency of experienced blackouts, and endured sexual or acquisitory crimes as a result of GHB use.MethodsSixty recreational GHB users filled out a questionnaire on experienced subjective, somatic, and sexual effects of GHB, the frequency of blackouts due to their GHB use, and items on their sexual experiences in relation to GHB use.ResultsOf the sample, 25.9% reported increased sexual arousal as well as more intense attraction towards their sexual partners and increased sexual openness when using GHB; 34.8% had sexual intercourse with strangers, or with others, but not with their partners when using GHB; and 8.6% were victims of acquisitory crimes, whereas 3.4% were victims of a sexual assault. Furthermore, 24.6% typically experienced blackouts when using GHB.ConclusionGamma‐hydroxybutyrate seems to be a potential substitute for both stimulant and depressant substances. Increased sexual desire and disinhibition may lead to a more frequent and potentially more riskful sexual activity. Experienced blackouts need to be considered as risk factors for suffering sexual or acquisitory crimes. Copyright © 2015 John Wiley & Sons, Ltd.
Doyen–Wilson Results for Odd Length Cycle Systems
Authors: Horsley Daniel , Hoyte Rosalind A. 
Published: July 2015

AbstractFor each odd , we completely solve the problem of when an m‐cycle system of order u can be embedded in an m‐cycle system of order v, barring a finite number of possible exceptions. In cases where u is large compared to m, where m is a prime power, or where , the problem is completely resolved. In other cases, the only possible exceptions occur when is small compared to m. This result is proved as a consequence of a more general result that gives necessary and sufficient conditions for the existence of an m‐cycle decomposition of a complete graph of order v with a hole of size u in the case where and both hold.
A multiproxy (micro‐XRF, pollen, chironomid and stable isotope) lake sediment record for the Lateglacial to Holocene transition from Thomastown Bog, Ireland
Authors: TURNER JONATHAN N. , HOLMES NAOMI , DAVIS STEPHEN R. , LENG MELANIE J. , LANGDON CATHERINE , SCAIFE ROBERT G. 
Published: July 2015

ABSTRACTA multiproxy Lateglacial environmental record is presented for a ca. 3.5‐m lacustrine sequence retrieved from a small basin (ca. 2 km2) at Thomastown Bog in County Meath, Ireland. Sediment chemistry, pollen, chironomid and stable isotope data provide a detailed picture of catchment and lake system changes from the end of the last glacial (GS‐2a) to the early Holocene that correspond closely to existing local and regional models of climate change. Concomitant adjustments in independent proxy records are matched to the NGRIP oxygen isotope curve giving 12 event‐episodes ranging from major climatic shifts to lower amplitude, centennial‐ to sub‐centennial‐scale adjustments, including a previously unreported regressive period of landscape instability during the north‐west European ‘Rammelbeek Phase’. The study emphasizes the potential of palaeoenvironmental reconstruction from sediment chemistry where the sediment mixing system reflects autochthonous versus allochthonous inputs. The investigation also indicates problems of interpreting isotope data derived from bulk marl due to possible lag effects controlling the delivery of soil and groundwater and multiple sources of HCO3– (aq.). These research findings have implications for core site selection and for studies attempting to use stable isotopes for correlation purposes.
The DNA index as a prognostic tool in hilar cholangiocarcinoma
Authors: Kamphues Carsten , Al‐Abadi Nadine , Bova Roberta , Rademacher Sebastian , Al‐Abadi Hussein , Klauschen Frederick , Bahra Marcus , Neuhaus Peter , Pratschke Johann , Seehofer Daniel 
Published: July 2015

Background and ObjectivesDue to the devastating prognosis of patients suffering from hilar cholangiocarcinoma (HCCA) valid prognostic factors are urgently needed to guide treatment decisions in a personalized concept. The aim of this study was to analyze the predictive value of the DNA index in a large single‐center cohort of patients undergoing resection of HCCA.MethodsA total of 154 patients who underwent resection of HCCA were included in this prospective study. The DNA index was assessed by image cytometry of fresh tumor samples and correlated, as well as standard histopathological parameters, with patient survival.ResultsThe median DNA index was 1.61 ± 0.32. Univariate survival analysis identified eight parameters including DNA index, but not DNA ploidy as prognostic markers. In the Cox proportional hazard model DNA index (P = 0.021), tumor size (P = 0.029) and lymph nodes status (P = 0.039) could be shown to be independent predictors of patient survival.ConclusionThe DNA index represents an independent prognostic marker in HCCA which is superior to most standard histopathological factors. Since the DNA index can be assessed not only post‐ but also preoperatively, it might be a potential tool in the preoperative decision‐making process. J. Surg. Oncol. 2015 111:214–218. © 2015 Wiley Periodicals, Inc.
Halomethane production by vanadium‐dependent bromoperoxidase in marine Synechococcus
Authors: Johnson Todd L. , Brahamsha Bianca , Palenik Brian , Mühle Jens 
Published: July 2015

AbstractTo investigate the role of vanadium‐dependent bromoperoxidase (VBPO) for the production of halogenated methanes in marine prokaryotes, we measured VBPO activity and halomethane production in two strains of Synechococcus; one with VBPO (strain CC9311) and one without VBPO (strain WH8102). A mutant strain of CC9311, VMUT2, in which the gene for VBPO is disrupted, was also tested. A suite of halomethanes was measured in the headspace above cultures as well as in the culture medium with a purge‐and‐trap method. Monohalomethanes were the most consistently produced molecules among the three strains tested. Additionally, CC9311 produced 301 ± 109 molecules cell−1 d−1 of bromoform (CHBr3) when VBPO activity was detected, while production was not significantly different from zero when VBPO activity was not detected. VBPO activity and CHBr3 production were only detected when cultures of CC9311 were stirred, which may contribute to the often moderate to weak correlations between CHBr3 concentration and biological markers in the ocean. No production was seen by VMUT2 or WH8102. These data show that CHBr3 production rates are dramatically increased with or exclusive to the presence of VBPO, supporting its involvement in CHBr3 synthesis. This study thus provides genetic evidence that certain strains of marine Synechococcus, under particular conditions, can be a natural source of marine CHBr3, which contributes to ozone depletion in the stratosphere.
Nitrogen loads explain primary productivity in estuaries at the ecosystem scale
Authors: Woodland Ryan J. , Thomson James R. , Mac Nally Ralph , Reich Paul , Evrard Victor , Wary Fiona Y. , Walker Jeffrey P. , Cook Perran L. M. 
Published: July 2015

AbstractIncreased nutrient loads stimulate estuary primary productivity and can alter the structure and function of biological communities within estuaries, particularly when producer groups respond differently to changes in nutrient availability. Here, the relative influence of riverine inputs of nitrogen and phosphorus were compared to determine their contribution to estuarine primary producers at large spatial scales. Indices of demersal (extent of macroalgae relative to other vegetation, total shallow water area vegetated) and planktonic (seasonally averaged chlorophyll concentration) primary producer communities were derived at whole‐of‐ecosystem scales in 14 estuaries dispersed across a longitudinal gradient using aerial imaging, underwater videography and in situ monitoring. A model selection framework was used to relate annual nutrient loads (total nitrogen [TN], dissolved inorganic nitrogen [DIN], total phosphorus [TP]), sediment loads (TSS), molar stoichiometric load ratios (TNM: TPM), and estuary water residence times to the demersal and planktonic indices. Dissolved inorganic nitrogen was the best predictor of the extent of macroalgae, total vegetation coverage, and the concentration of planktonic chlorophyll. Rapid increases in all three indices occurred at inorganic nitrogen loads of ∼ 5–10 Mg km−2 yr−1. There was some evidence that TNM: TPM, TP and TSS loads were informative model covariates. Relative to DIN loads, TP loads were a poor predictor of the macroalgal and planktonic indices. These findings underscore the critical role of catchment‐derived nitrogen in contributing to producer communities at the whole‐of‐ecosystem scale and support the growing consensus that nitrogen loads (in addition to phosphorus) must be managed to effectively alleviate eutrophication in estuaries.
Location performance fading for multiple disturbances in distributed Sagnac optical fiber interferometer
Authors: Wang Bingjie , Pi Shaohua , Jia Bo , Sun Qi , Zhao Dong 
Published: July 2015

ABSTRACTFour situations of multiple disturbances, pulse to pulse, pulse to ultrasonic, ultrasonic to ultrasonic, and triple ultrasonic at different distances have been tested and located by an improved twice‐fast Fourier transform (FFT) algorithm in this article. The spectrum of the phase difference is performed by autocorrelation to improve peak concentration. Location performance decays to 57 m and 181 m when pulse and ultrasonic are applied at 100 km and 90 km simultaneously. Moreover, the energy ratio of one disturbance to others should be no less than 0. 3825 to be correctly located, which means that the number of detectable disturbances limits to three. © 2015 Wiley Periodicals, Inc. Microwave Opt Technol Lett 57:2294–2298, 2015
A compact dual‐band frequency‐reconfigurable textile antenna for wearable applications
Authors: Tahir Farooq A. , Javed Ambreen 
Published: July 2015

ABSTRACTThis communication presents a flexible, low‐profile, frequency‐tunable textile antenna for body area wireless communication. The antenna operates in both instrument, scientific and measurment (ISM), 2.45 GHz and wireless local area network (WLAN), 5 GHz bands. It features with an overall 5 × 23.5 mm2 compact planar geometry consisting of a well‐optimized slotted radiating patch fabricated using conductive copper tape on Denim material as a very common flexible textile substrate. The antenna radiates unidirectionally, and the ground plane made up with copper tape avoids radiation coupling to the users’ body. A single PIN diode with simple biasing circuitry is used to tune the antenna between the two operating bands. The performance of the antenna in free space as well as under bending conditions and when placed on the body is presented. © 2015 Wiley Periodicals, Inc. Microwave Opt Technol Lett 57:2251–2257, 2015
A new frequency‐reconfigurable antenna using coupling patterns for mobile handsets
Authors: Lee Won‐Woo , Cho Yong‐Sang 
Published: July 2015

ABSTRACTThis letter focuses on the design of a new frequency‐reconfigurable antenna for a mobile handset application. The proposed antenna supports the most important long‐term evolution bands: band 17 (704–746 MHz), band 13 (746–787 MHz), band 5 (824–894 MHz), and band 8 (880–960 MHz). A digital variable capacitor (DVC) is used via a coupling pattern proximity to the aperture of an inverted F antenna (IFA) to which a single‐pole single throw RF switch is connected to take advantages of the two different kinds of tuning elements. We show that the proposed antenna is able to have a quasicontinuous and wide range of frequency tuning capabilities over 700–960 MHz through simulations and experiments. We also show that the coupled aperture used for connection of the DVC to the aperture of IFA is helpful for reducing the ohmic losses in the DVC from the antenna efficiency degradation which is the most important figure of merit for frequency reconfigurable antennas based on the active tuning elements. © 2015 Wiley Periodicals, Inc. Microwave Opt Technol Lett 57:2333–2336, 2015
CDR antenna with dual‐band 1.9/2.7 GHz for MIMO‐LTE terminals
Authors: Messaoudene Idris , Denidni Tayeb A. , Benghalia Abdelmadjid 
Published: July 2015

ABSTRACTIn this letter, we present a compact dual‐band dielectric resonator antenna for multi‐input multi‐output antenna is designed and fabricated. The proposed antenna consists of a single cylindrical dielectric resonator antenna (CDRA) excited from two orthogonal ports. The electromagnetic analysis is performed using the CST microwave studio software. To validate the proposed concept, experimental measurements are also performed. The measured results show that the CDRA provides two bands around 1.9 and 2.7 GHz, suitable for LTE applications. Moreover, the proposed design allows a very good isolation between the two ports and a low envelop correlation coefficient. © 2015 Wiley Periodicals, Inc. Microwave Opt Technol Lett 57:2388–2391, 2015
Bioinspired multiobjective synthesis of X‐band FSS via general regression neural network and cuckoo search algorithm
Authors: Neto M. C. Alcantara , Araújo J. P. L. , Barros F. J. B. , Silva A. N. , Cavalcante G. P. S. , D'Assunção A. G. 
Published: July 2015

ABSTRACTA bioinspired hybrid multiobjective optimization technique that associates a general regression neural network and a cuckoo search algorithm is proposed for microwave applications. This study is focused on the simulation, design, and synthesis of frequency selective surfaces (FSSs) with triangular ring patch elements printed on fiberglass substrates (FR4). The proposed technique aims, for example, to design FSSs with specific values for the resonance frequency and bandwidth in the frequency range from 8 to 12 GHz. For validation purpose, a bandstop FSS filter, centered at 11 GHz and with a 4 GHz bandwidth, was synthesized, fabricated, and measured. Good agreement between simulated and measured results is reported. © 2015 Wiley Periodicals, Inc. Microwave Opt Technol Lett 57:2400–2405, 2015
PMMA microfiber coated with al‐doped ZnO nanostructures for detecting uric acid
Authors: Irawati N. , Harun S. W. , Adwan S. , Alnowami M. , Ahmad H. 
Published: July 2015

ABSTRACTA biosensor is demonstrated using the fabricated polymethyl methacrylate (PMMA) microfiber, which is coated with Al‐doped ZnO nanostructure using a sol‐gel process, used as the probe. The change in the transmitted light intensity from the PMMA microfiber‐based sensor with the increase in uric acid concentration is investigated. It is observed that the light power linearly decreases with the increase in uric acid concentration. As the uric acid concentration increases from 0 to 500 ppm, the transmitted light intensity reduces from −31.54 to −36.54 dBm. It is found that the sensor has a sensitivity of 0.010 dB/ppm with a good linearity of more than 99%. © 2015 Wiley Periodicals, Inc. Microwave Opt Technol Lett 57:2455–2457, 2015
A novel dual‐band antenna based on corrugated slotted‐complementary split‐ring resonators
Authors: Sassi Imene , Talbi Larbi , Hettak Khelifa 
Published: July 2015

ABSTRACTThis article presents the design of a dual‐band microstrip patch antenna. The proposed patch antenna is based on a novel metamaterial structure named the corrugated slotted‐complementary split‐ring resonators. By loading this new inclusion on the ground plane of a conventional patch antenna, a second resonance frequency can be created. The corrugated slotted split‐ring resonator has a minor effect on the first operating band which is generated by the patch. A prototype of this antenna has been designed for operation on the industrial‐scientific‐medical band (2.4 GHz) and the WLAN band (5.8 GHz). The prototype has been fabricated and measured, achieving good performances for both resonance frequencies. A good agreement between experimental and simulation results is obtained. © 2015 Wiley Periodicals, Inc. Microwave Opt Technol Lett 57:2310–2315, 2015
Measuring superdirective electrically small antenna arrays mounted on PCBs
Authors: Haskou Abdullah , Collardey Sylvain , Sharaiha Ala 
Published: July 2015

ABSTRACTThis article addresses the problem of measuring superdirective electrically small antennas mounted on printed circuit broads (PCBs). Different configurations for connecting the excitation system (SMA connector and coaxial cable) to an array of 31 × 25 mm2 integrated in a PCB of 110 × 70 mm2 are studied. This configurations are evaluated based on the cable effect on the array's input reflection coefficient and radiation pattern. Obtained results show that properly connecting the cable with the array mitigates its effect, and hence, it can be measured. © 2015 Wiley Periodicals, Inc. Microwave Opt Technol Lett 57:2269–2274, 2015
Internet Versus DVD Decision Aids for Hip and Knee Osteoarthritis
Authors: Allen Kelli D. , Sanders Linda L. , Olsen Maren K. , Bowlby Lynn , Katz Jeffrey N. , Mather Richard C. , Williams John W. 
Published: July 2015

AbstractIntroductionDecision aids (DAs) can improve multiple decision‐making outcomes, but it is not known whether different formats of delivery differ in their effectiveness or acceptability. The present study compared the effectiveness and acceptability of internet and DVD formats of DAs for osteoarthritis (OA).MethodsPatients with hip or knee OA were randomized to view an internet or DVD format DA, which provided information on OA treatments. Measures were collected at baseline, immediately after viewing the DA and then 30 days later. Outcomes included: Hip/Knee OA Decision Quality Instrument – Knowledge Subscale (HK‐DQI Knowledge), Decisional Conflict Scale (DCS), Preparation for Decision Making Scale (PDMS), Stage of Decision Making, and Acceptability of DAs. Generalized estimating equations (GEE) were used to examine changes in HK‐DQI Knowledge and DCS scores over time, between decision aid groups and within the sample overall. Group differences in the PDMS scale (assessed once, immediately after DA viewing) were estimated using a Wilcoxon rank sums test.ResultsAmong 155 participants in the study, the mean age was 61.8 years, 60.6% were women and 58.1% were Caucasian. HK‐DQI Knowledge scores improved over time (p < 0.001), although there was some attenuation by the 30‐day follow‐up; there was no difference between the two DA groups (p = 0.448). DCS scores decreased markedly for both groups (p < 0.001) and improvements were maintained by the 30‐day follow‐up (means: internet: baseline = 25.0, 30‐day = 6.9; DVD: baseline = 25.0, 30‐day = 6.2); there was no difference between the two DA groups (p = 0.808). PDMS scores were higher for the DVD group than the internet group (85.2 versus 74.9, p = 0.005). Stage of Decision Making became more certain after viewing the DA for both groups, with even more certainty indicated at 30‐day follow‐up. Acceptability items indicated positive perceptions of both DAs.DiscussionInternet and DVD DAs were associated with meaningful, comparable improvements in decision‐making outcomes in patients with knee and hip OA. DAs are inexpensive to disseminate and could be valuable tools for enhancing care for OA. Copyright © 2015 John Wiley & Sons, Ltd.
A general approximation of the exponential Cauchy–Born hypothesis to model arbitrarily shaped shell‐like nanostructures within continuum mechanics
Authors: Findeisen Claudio , Wackerfuß Jens 
Published: July 2015

SummaryIn this paper, a continuum membrane theory and its subsequent finite element approximation for the description of arbitrary shell‐like nanostructures such as graphene‐based nanostructures is presented. This is carried out by applying a multiscale approach where the continuum membrane is linked to the underlying atomistic lattice. This linkage is performed by the exponential generalization of the Cauchy–Born hypothesis, because the classical Cauchy–Born hypothesis is restricted to three‐dimensional bulk structures and is thus not applicable to shell‐like structures. However, the approximations of the exponential Cauchy–Born hypothesis published so far are limited to structures with a planar reference configuration. In this paper, we present an extended approximation, which does not require the reference configuration to be planar and is thus applicable to arbitrarily shaped shell‐like nanostructures. A detailed elaboration of the related finite element implementation with important computational aspects is presented. Finally, the accuracy of the proposed method and its implementation is verified with several numerical examples. Copyright © 2015 John Wiley & Sons, Ltd.