bluuebunny/crossref_metadata_2025_split huggingface dataset:
Relations between adolescent perceptions of household chaos and externalizing and internalizing behaviors in low‐ and middle‐income families
Authors: Hunter‐Rue Daniesha S. , Miller Portia , Hanson Jamie L. , Votruba‐Drzal Elizabeth 
Published: August 2024

AbstractA large body of literature has established that chaos in the home environment, characterized by high levels of disorganization, lack of household routine, crowding, noise, and unpredictability, undermines social–emotional and behavioral development in early childhood. It is less clear whether household chaos is linked to elevated risk for behavior problems in adolescence. The aims of this study were 3fold: (1) characterize the variability of adolescent and caregiver reports of household chaos over time; (2) examine associations among caregiver and adolescent reports of chaos over a 9‐month period; (3) consider how between‐ and within‐ individual variability in household chaos predicts adolescent externalizing and internalizing problems. This study drew data from the Family Income Dynamics study, a 9‐month longitudinal study. Participants included 104 adolescents between 14 and 16 years old (55% female; M age = 14.85) and their caregiver (92% female) from low‐ and middle‐income families. Results showed that adolescent‐reports of household chaos were more variable over time compared to caregivers' reports. Adolescent‐reports of household chaos had positive within‐ and between‐level associations with externalizing problems and between‐level associations with internalizing, while caregiver‐reports of chaos had no links to behavior. This work highlights the importance of adolescents' own perceptions of household chaos when considering its links to adolescent development.
Improved estimation of dynamic models of conditional means and variances
Authors: Wang Weining , Wooldridge Jeffrey M. , Xu Mengshan 
Published: August 2024

Using ‘working’ assumptions on conditional third and fourth moments of errors, we propose a method of moments estimator that can have improved efficiency over the popular Gaussian quasi‐maximum likelihood estimator (GQMLE). Higher‐order moment assumptions are not needed for consistency – we only require the first two conditional moments to be correctly specified – but the optimal instruments are derived under these assumptions. The working assumptions allow both asymmetry in the distribution of the standardized errors as well as fourth moments that can be smaller or larger than that of the Gaussian distribution. The approach is related to the generalized estimation equations (GEE) approach – which seeks the improvement of estimators of the conditional mean parameters by making working assumptions on the conditional second moments. We derive the asymptotic distribution of the new estimator and show that it does not depend on the estimators of the third and fourth moments. A simulation study shows that the efficiency gains over the GQMLE can be non‐trivial.
Exploring resource patch occupancy: patch size, but not connectivity, explains the abundance of spider kleptoparasites in golden orb webs
Authors: Gregorič M. , Quiñones‐Lebrón S. G. , Kuntner M. , Agnarsson I. 
Published: August 2024

AbstractThe ideal free distribution (IFD) theory predicts that individuals are free to move among habitat patches and distribute among them “ideally,” in order to maximize individual evolutionary fitness. Size and quality of habitat patches then should directly impact the number of individuals occupying them, and connectivity of habitat patches likely plays a role if dispersal is limited. However, habitat patches can be distributed so that movement no longer can be considered free, for example, when patches are isolated. Challenges stemming from patch delimitation and detection rate of occupants further complicate efforts attempting to resolve such patterns. Here, we utilize as habitat patches the orb webs of four different populations belonging to three golden orb weaver spider species, Nephila pilipes (Fabricius, 1793), Nephilingis livida (Vinson, 1863), and Trichonephila clavipes (Linnaeus, 1767), and the obligate spider kleptoparasites (Argyrodinae, Theridiidae) that are associated with their webs. We examine how the IFD predicts the abundance of kleptoparasites under different patterns of patch size and distribution. We found that larger host webs, that is, habitat patches that contain more resources, are occupied by a higher number of kleptoparasitic spiders, regardless of their degree of isolation. Although the free movement prediction is often violated in natural systems, we find no evidence for habitat patch connectivity affecting the abundance of kleptoparasites, indicating that their dispersal ability facilitates the location and colonization of habitat patches regardless of their isolation. Therefore, our results support the interaction between argyrodine kleptoparasitic spiders and the webs of golden orb weavers to be a suitable natural system for studying the IFD.
Reproductive health from hair: Validation and utility of hair progesterone analysis in the Asian black bear, Ursus thibetanus
Authors: Shimamoto T. , Taki T. , Kumaki A. , Motohashi A. , Tamatani H. , Oshima G. , Tanaka J. , Yamamoto T. 
Published: August 2024

AbstractHair hormone analysis has received increasing attention in the fields of wildlife management and conservation over the last decade. However, few studies focused on sex steroid hormones, even though hair sex steroid hormone analysis has the potential to provide information on an individual's reproductive health, leading to a better understanding of animal reproductive biology and the assessment of individual and population health. Here, we tested the assay validation and examined whether hair progesterone concentration (HPC) differs between different sexes and age classes in the Asian black bear, Ursus thibetanus. We also investigated the effects of reproductive condition, age, and body condition index (BCI) on HPC to determine the utility of hair progesterone analysis in bears. The assay validation was reported in our study. We found a significantly higher HPC in adult females than in juvenile females and juvenile and adult males. In addition, we found no effects of age and BCI on HPC but a significant positive effect of reproductive condition, as the HPC in breeding adult females was significantly higher than in nonbreeding adult females. These results suggest that hair progesterone analysis has the potential to evaluate the reproductive condition of Asian black bears.
Optimizing pediatric tonsillectomy outcomes with an opioid sparing anesthesia protocol: Learning and continuously improving with real‐world data
Authors: Chiem Jennifer L. , Franz Amber M. , Hansen Elizabeth E. , Verma Shilpa T. , Stanzione Taylor F. , Bezzo Leah K. , Richards Michael J. , Parikh Sanjay R. , Dahl John P. , Low Daniel K. , Martin Lynn D. 
Published: August 2024

AbstractIntroductionThis quality improvement initiative is a continued pursuit to optimize outcomes by iteratively improving our opioid sparing anesthesia protocol for tonsillectomy with or without adenoidectomy at our pediatric ambulatory surgical center through data driven Plan‐Do‐Study‐Act cycles.MethodsFrom 1/2015 through 12/2023, our standardized tonsillectomy protocol underwent nine procedure‐specific perioperative Plan‐Do‐Study‐Act cycles, three procedure‐specific postoperative prescription Plan‐Do‐Study‐Act cycles, and four general ambulatory surgical center enhanced recovery Plan‐Do‐Study‐Act cycles. We analyzed data from the medical record using statistical process control charts. The primary outcome measure was the percent of patients requiring intravenous opioid in the post anesthesia care unit. Secondary outcomes included maximum post anesthesia care unit pain score, the percent of patients requiring treatment for nausea and/or vomiting in the post anesthesia care unit, and the number of postoperative opioid prescription dosages. Balancing measures were average post anesthesia care unit length of stay, percent of patients with prolonged Post Anesthesia Care Unit length of stay (>120 min), and 30‐day reoperation rate.ResultsA total of 5654 tonsillectomy with or without adenoidectomy cases were performed at our ambulatory surgical center from 2015 to 2023. The incidence of intravenous opioid administered in the post anesthesia care unit initially rose with opioid free anesthesia launch, but subsequently decreased below the target of 10%. Maximum post anesthesia care unit pain scores rose from mean 3.6 to 4.5, but subsequently returned to the baseline of 3.5, while the incidence of postoperative nausea and/or vomiting improved. The average post anesthesia care unit length of stay increased by 10 min with opioid free anesthesia; however, prolonged post anesthesia care unit stay and 30‐day reoperation rates were unchanged.ConclusionsThe continued refinement of our opioid sparing anesthesia protocol has led to reduced perioperative and home opioid use, stable maximum post anesthesia care unit pain scores, and improved postoperative nausea and vomiting rates, with only a slight increase in mean post anesthesia care unit length of stay.
Design and Analysis of an Automotive Crash Box Using Strut-Based Lattice Structures
Authors: K Sai Susanth , Murugan Ramu , S Chidambara Raja , Doutre Pierre-Thomas , Vignat Frederic 
Published: August 2024

Abstract
Crash boxes play a crucial role in cars by serving as energy-absorbing components, typically located at the front end. They are intentionally designed to collapse in a controlled manner during frontal collisions. The objective of this research is to enhance the energy absorption capabilities of crash boxes through the integration of strut-based lattice patterns. Initially, crash boxes of various geometries suitable for lattice insertion were selected and optimized by analyzing their energy absorption capacity using Abaqus software. The analysis revealed that the square crash box exhibited the highest energy absorption. Subsequently, the procedure entailed integrating various unit cell-based lattice patterns into square crash box. These constructed models were subjected to simulations to evaluate their specific energy absorption (SEA) performance, which is ratio of energy absorbed to its mass. The simulation outcomes conclusively determined the body-centered cubic (BCC) crash box as the most effective among the considered structures. During optimization, fine-tuning the BCC crash box has been done by adjusting unit cell dimensions and strut diameter, which boosts energy absorption by 30.16% compared to the initial square crash box. While comparing present structures with honeycomb structures, the peak load values in present structures are lower than those in honeycomb structures.
Development of a Virtual Patient Generator for Simulation of Vasopressor Resuscitation
Authors: Kao Yi-Ming , Chalumuri Yekanth Ram , Sampson Catherine M. , Shah Syed A. , Salsbury John R. , Tivay Ali , Kinsky Michael , Kramer George C. , Hahn Jin-Oh 
Published: August 2024

Abstract
This paper presents a virtual patient generator (VPG) intended to be used for preclinical in silico evaluation of autonomous vasopressor administration algorithms in the setting of experimentally induced vasoplegia. Our VPG consists of two main components: (i) a mathematical model that replicates physiological responses to experimental vasoplegia (induced by sodium nitroprusside (SNP)) and vasopressor resuscitation via phenylephrine (PHP) and (ii) a parameter vector sample generator in the form of a multidimensional probability density function (PDF) using which the parameters characterizing the mathematical model can be sampled. We developed and validated a mathematical model capable of predicting physiological responses to the administration of SNP and PHP. Then, we developed a parameter vector sample generator using a collective variational inference method. In a blind testing, the VPG developed by combining the two could generate a large number of realistic virtual patients (VPs), which could simulate physiological responses observed in all the experiments: on the average, 98.1% and 74.3% of the randomly generated VPs were physiologically legitimate and adequately replicated the test subjects, respectively, and 92.4% of the experimentally observed responses could be covered by the envelope formed by the subject-replicating VPs. In sum, the VPG developed in this paper may be useful for preclinical in silico evaluation of autonomous vasopressor administration algorithms.
A Practical Model of Balloon/Tissue Contact in Pulmonary Vein Isolation with Cryoballoon Ablation
Authors: Smith David J. , Murthy Sam , Liao Yu 
Published: August 2024

Abstract
Effective treatment of paroxysmal atrial fibrillation with pulmonary vein isolation via cryoballoon ablation is dependent on effective contact with the targeted tissue surface. A computational method for determining contact area between the inflated cryoballoon and a given left atrial anatomy (including the pulmonary veins which return blood to the left atrium) was developed to evaluate the potential benefit of multiple balloon sizes in any left atrial anatomical shape acquired by medical imaging (e.g. X-ray computed tomography). The balloon geometry and material properties were obtained from 3D scanning and material testing of a commercial cryoballoon (POLARx™ FIT cryoballoon catheter, Boston Scientific). The tissue model consists of a primary continuous layer of elastic material conforming to the inside surface of the left atrium and a support array of massless, stiff surfaces conforming to the tissue shape and connected to linear spring elements. A sensitivity study shows robustness of model outputs (e.g. balloon/tissue contact area proximal edge location) to a relevant range of balloon and tissue model parameters. Application of the model to post-procedure comparison of contact area for two different balloon sizes based on cine and X-ray CT imaging is discussed. The balloon/tissue contact model provides a balance between realistic prediction of tissue deformation and model complexity, offering potential for near-real-time application to clinical procedure planning.
Evaluation of Pressure Sensors in a Novel Neonatal Multifunctional Gastric Feeding Tube Capable of Vital Sign Monitoring
Authors: Salafian Iman , Dana Lynn El , Englert Angie , Li Wei , Groves Alan , Rylander Christopher G. 
Published: August 2024

Abstract
Premature births, a significant global health challenge, often result in various health complexities that require specialized neonatal intensive care. Traditional vital sign monitoring methods pose risks to the delicate skin and the overall health of premature infants. Non-invasive respiratory modalities in Neonatal Intensive Care Units, such as Continuous Positive Airway Pressure and High-flow Nasal Cannula, have notable drawbacks that limit their performance in providing effective respiratory support for these delicate patients. To overcome these challenges, we developed a multifunctional neonatal catheter that integrates feeding, vital sign monitoring, and internal respiratory feedback into a single, less invasive device. An air pressure sensor is a key component of this catheter. This study focuses on the preliminary testing of multiple pressure sensors as potential options for this catheter. Sensors underwent day-long drift and noise level analysis under varying air pressure conditions. Signal analysis was performed to enhance data clarity and find potential noise sources. Results indicated variations in sensor performance, with certain sensors demonstrating superior stability, minimal drift, and minimal noise levels, making them suitable for integration into the catheter. The findings can help to narrow down the options for the most viable sensor. More comprehensive studies are needed to evaluate the performance of the selected options for clinical use.
Micro Computed Tomography Imaging and Subsequent Quantifications of the Associated Changes in Cardiac Anatomies Relative to Various Methods of Specimen Fixation
Authors: DeVos Amanda N. , Iaizzo Paul A. 
Published: August 2024

Abstract
Various research studies utilize formalin to preserve cardiac tissues, which are then used to investigate and quantify cardiac anatomies and/or device-tissue interactions. However, it is known that various fixation processes will alter cardiac anatomies. One needs to quantify such and determine which fixation method may minimize these changes. To do so, human hearts were scanned fresh and then again after formalin fixation in an end-diastolic state using one of three different methods, including submerging, submerging while perfusing the coronaries, and submerging while pressurizing all four chambers. High resolution computational 3D models from micro computed tomography (micro-CT) scans were generated, and measurements of the aorta, right and left ventricle (RV and LV) lateral walls and septum thicknesses were performed and compared. The ventricular wall and septum thickness tended to increase after fixation; however, the degree of change was relatively inconsistent. Yet, pressurizing all four chambers internally seems to minimize the ventricular wall thickening and reduction in blood volume. Though, additional studies are needed to determine if this method will consistently reduce anatomical changes and if the changes are constant or predictable over a large sample size. Regardless of the fixation method, an average 1.4 mm of LV and 4 mm of RV wall thickening were observed, which may contribute to potential error in anatomical measurements within fixed hearts. Therefore, one needs to consider fixation methods of study specimens and how it changes the given cardiac anatomies when performing pre-clinical studies on formalin fixed human hearts.
Bacterial community composition of wheat aboveground compartments correlates with yield during the reproductive phase
Authors: Fu Xiao , Ma Yuying , Yang Teng , He Shuobing , Wang Daozhong , Jin Lin , Zhan Linchuan , Guo Zhibin , Fan Kunkun , Li Jiasui , Chu Haiyan 
Published: August 2024

ABSTRACT

Plant-associated microbial communities play important roles in agricultural productivity, and their composition has been shown to vary across plant compartments and developmental stages. However, the response of microbial communities within different plant compartments and at different developmental stages to diverse long-term fertilization treatments, as well as their linkages with crop yields, remains underexplored. This study analyzed wheat-associated bacterial communities within various soil and plant compartments under three fertilization treatments throughout the vegetative and reproductive phases. The variance in bacterial community was primarily attributed to compartments, followed by fertilization treatments and developmental stages. The composition of belowground bacterial communities (bulk soil, rhizosphere soil, and root) exhibited stronger responses to fertilization treatments than aboveground compartments (stem and leaf). The composition of belowground bacterial communities responded to fertilization treatments at all developmental stages, and it was significantly correlated with crop yields during the vegetative phase, whereas the aboveground community composition only showed a response to fertilization during the reproductive phase, at which point it was significantly correlated with crop yields. Moreover, during this reproductive phase, the co-occurrence network of aboveground bacterial communities exhibited enhanced complexity, and it contained an increased number of keystone species associated with crop yields, such as
Sphingomonas
spp.,
Massilia
spp., and
Frigoribacterium
spp. Structural equation modeling indicated that augmenting total phosphorus levels in aboveground compartments could enhance crop yields by increasing the relative abundance of these keystone species during the reproductive phase. These findings highlight the pivotal role of aboveground bacterial communities in wheat production during the reproductive phase.

IMPORTANCE
The developmental stage significantly influences crop-associated bacterial communities, but the relative importance of bacterial communities in different compartments to crop yields across various stages is still not well understood. This study reveals that belowground bacterial communities during the vegetative phase are significantly correlated with crop yields. Notably, during the reproductive phase, the composition of aboveground bacterial communities was significantly correlated with crop yields. During this phase, the complexity and enriched keystone species within the aboveground co-occurrence network underscore their role in boosting crop production. These results provide a foundation for developing microbiome-based products that are phase-specific and promote sustainable agricultural practices.
16S rRNA gene sequencing of microbiota from the preen oil and cloaca of chipping sparrows (
Spizella passerina
)
Authors: Van Laar Tricia A. , Greenberg Jonathan M. , Theis Kevin R. , Whittaker Danielle J. , Slade Joel W. G. 
Published: August 2024

ABSTRACT

We present the results of 16S rRNA gene amplicon sequencing of the microbiota from preen oil and the cloaca of chipping sparrows (
Spizella passerina
) collected near Mountain Lake Biological Station in Pembroke, VA.
Functional Analysis of the Channelrhodopsin Genes from the Green Algae of the White Sea Basin
Authors: Karpova Olga V. , Vinogradova Elizaveta N. , Moisenovich Anastasiya M. , Pustovit Oksana B. , Ramonova Alla A. , Abramochkin Denis V. , Lobakova Elena S. 
Published: August 2024

Abstract
Optogenetics, the method of light-controlled regulation of cellular processes is based on the use of the channelrhodopsins that directly generate photoinduced currents. Most of the channelrhodopsin genes have been identified in the green microalgae Chlorophyta, and the demand for increasing the number of functionally characterized channelrhodopsins and the diversity of their photochemical parameters keeps growing. We performed the expression analysis of cation channelrhodopsin (CCR) genes in natural isolates of microalgae of the genera Haematococcus and Bracteacoccus from the unique Arctic Circle region. The identified full-length CCR transcript of H. lacustris is the product of alternative splicing and encodes the Hl98CCR2 protein with no photochemical activity. The 5′-partial fragment of the B. aggregatus CCR transcript encodes the Ba34CCR protein containing a conserved TM1-TM7 membrane domain and a short cytosolic fragment. Upon heterologous expression of the TM1-TM7 fragment in CHO-K1 cell culture, light-dependent current generation was observed with the parameters corresponding to those of the CCR. The first discovered functional channelrhodopsin of Bracteacoccus has no close CCR homologues and may be of interest as a candidate for optogenetics.
Synthesis and Structure of Copper(I) Halide Complexes with Halogen-Functionalized Isocyanide Ligands
Authors: Vlasova V. , Toikka Yu. N. , Suslonov V. V. , Smirnov A. S. , Bokach N. A. 
Published: August 2024

Abstract
Eleven copper(I) halide complexes [CuX(CNR)3] (X = Cl, Br; R = C6H3-2,6-Cl2, C6H3-2-Cl-6-Me, C6H3-2,6-Br2, C6H3-2-Br-6-Me; X = I, R = C6H3-2,6-Cl2, C6H3-2-Cl-6-Me, C6H3-2-Br-6-Me) bearing halogen-functionalized aromatic isocyanide ligands were synthesized. The compounds were characterized by atomic emission spectroscopy (Cu), IR, 1H NMR spectroscopy and high-resolution mass spectrometry. The structure of nine compounds was determined by X-ray diffraction. Structural studies allow to reveal that the supramolecular structure of the complexes is based on weak C–H···X (X = Cl, Br, I) interactions and π-stacking of the aromatic rings of isocyanide ligands.