bluuebunny/crossref_metadata_2025_split huggingface dataset:
Intervención arqueológica, estudio constructivo y restitución volumétrica de la torre-puerta bajomedieval del Pont del Vidre (Llíria, Valencia)
Authors: Sánchez Signes Miquel , Vicente Gabarda Miguel , Pérez Milián Ramiro 
Published: February 2025

The Pont del Vidre gate-tower is a defensive construction dating from the 14th century, belonging to the Christian walled circuit of Llíria, Valencia. Until 2020 it was in a poor state of conservation, which led to an action aimed at its archaeological and constructive study and its enhancement, with the aim of establishing its dating, function and the characteristics of its masonry. In this way, a faithful restitution of its original appearance could be undertaken and its relationship with its surroundings could be better understood. Measurements and techniques were recovered that provide us with a great deal of information. This important landmark of late medieval Llíria, an intermediate agricultural town in the Kingdom of Valencia, and the evolution of the tower up to the present day are presented.
Comment on “Estimating the Maximum Magnitude of Induced Earthquakes in the Groningen Gas Field, the Netherlands” by Julian Bommer, Jan van Elk, and Mark Zoback
Authors: Vlek Charles 
Published: February 2025

ABSTRACT
In their “Estimating the maximum magnitude of induced earthquakes in the Groningen gas field, the Netherlands,” Bommer, van Elk, and Zoback (BvEZ) present good reasons to revise the 2022 expert-panel assessment of the maximum possible earthquake magnitude (Mmax) in the Groningen gas field, but their timing (August 2024) and authorship are remarkable. Here, it is argued that: (1) induced Mmax arises from a changing seismic source, (2) effective safety communication requires clarification of the practical meaning of “logic tree,” “expert weight,” and “possible” versus “expected,” (3) multivariate sensitivity analysis is needed to appreciate the implications of Mmax, for example, surface (vibratory) ground movements, (4) independent peer review may be useful but too much asked, and that (5) possible conservatism in Mmax assessment may be due to (costly) precautionary reasoning under uncertainty. The importance of balanced multiparty risk communication is emphasized. Concluding remarks are about institutional responsibilities for (apparently) insufficient Mmax assessment in 2022, the implications of BvEZ’s current re-evaluation for further building reinforcement and restoration policies for Groningen, and the desirability of reviving the expert assessment process on Mmax, to validate BvEZ’s main proposal that, for Groningen, 3.6≤Mmax≤4.1. After the field’s recent closure, ever observable Mmax will probably never exceed the historical earthquake magnitude of 3.6 near Huizinge in 2012.
Reply to “Comment on ‘Estimating the Maximum Magnitude of Induced Earthquakes in the Groningen Gas Field, the Netherlands’ by Julian J. Bommer, Jan van Elk, and Mark D. Zoback” by Charles Vlek
Authors: Bommer Julian J. , van Elk Jan , Zoback Mark D. 
Published: February 2025

ABSTRACT
In Bommer et al. (2024), we presented a critical review of the process through which the current logic tree for the maximum magnitude used in seismic hazard and risk calculations for induced earthquakes in Groningen was obtained. The article intended to initiate a discussion for which our premise is that the current maximum magnitude distribution may be excessively conservative, impacting both the quantitative risk assessment and the public and regulatory perception of risk. In his Comment, Vlek (2024b) misrepresents our article and makes inferences that have no basis in our article. He also puts forward numerous ideas, many of which have no connection to our article and others of which seem to reflect statements that we make, despite having recently published a discursive article on this very topic. There are several serious technical weaknesses in the comment, which we explain in this reply to minimize the confusion that the comment could create.
Remote Single-Station Seismic Monitoring of the July–October 2022 Earthquake Swarm at Ta‘ū Volcano, American Samoa
Authors: Yoon Clara E. , Skoumal Robert J. , Michael Andrew J. , Jolly Arthur D. , Ellis Andria P. , Downs Drew T. , Dotray Peter J. , Deligne Natalia I. , Chang Jefferson C. , Bennington Ninfa , Wech Aaron , Haney Matthew , Hotovec-Ellis Alicia J. , Lutu-McMoore Elinor , Langkilde Marcus 
Published: February 2025

Abstract
From July to October 2022, a noneruptive volcanic earthquake swarm occurred within ∼15 km of Ta‘ū Island, located in eastern American Samoa. Felt reports from residents were the only available information about the swarm when it started, as American Samoa lacked a seismic monitoring network. We developed a consistent single-station catalog for the entire swarm, using seismic data from the nearest station IU.AFI, ∼250 km away. We applied the EQTransformer deep-learning model (Mousavi et al., 2020), automatically picking Pn and Sn arrivals on IU.AFI continuous data. We retained only events with Sn–Pn times of 22.5–25 s, consistent with the expected locations based on felt reports, then detected smaller swarm events with subsequent template-matching. This single-station catalog characterized the swarm’s onset and escalation to peak activity before a multiagency field response team installed a local seismic network in mid-August 2022. This permanent seismic network captured the swarm’s decline. EQTransformer identified short S–P times on the first two locally deployed seismometers, both Raspberry Shake sensors, to constrain the swarm’s distance from Ta‘ū Island. Modern seismological processing methods, combined with basic observations such as felt reports, can quickly contribute useful information during an earthquake response in a poorly monitored region.
From thread to yarn, and yarn to thread: a complex case of persistent left superior vena cava
Authors: Dołęga Julia , Lekston Natalia , Krzywiecka Karolina , Machnik Aleksandra , Mizia-Stec Katarzyna 
Published: February 2025

WprowadzeniePrzetrwała lewa żyła główna górna (<i>persistent left superior vena cava</i> – PLSVC) jest rzadką anomalią krążenia żylnego, wynikającą z nieprawidłowości w embriogenezie. Występuje u 0,3–0,5% ogólnej populacji oraz nawet u 4,3% pacjentów z wadami serca. Powstaje na skutek połączenia lewej żyły podobojczykowej i żyły szyjnej wewnętrznej, przechodzi przez lewą stronę śródpiersia i zazwyczaj uchodzi do prawego przedsionka przez zatokę wieńcową. Zwykle jest bezobjawowa i często wykrywana przypadkowo podczas badań obrazowych układu krążenia. Może współistnieć z ubytkiem przegrody międzyprzedsionkowej (<i>atrial septal defect</i> – ASD).Opis przypadku52-letnia pacjentka z utrwalonym migotaniem przedsionków, przebytym udarem niedokrwiennym lewej półkuli mózgu, niekontrolowanym nadciśnieniem tętniczym i rozpoznanym ASD typu 2 została skierowana na izolcję żył płucnych (<i>pulmonary vein isolation</i> – PVI) z powodu objawowej arytmii o nasileniu IIb według European Heart Rhythm Association i klasy II według New York Heart Association. Po nieudanej PVI podjęto próbę kardiowersji farmakologicznej, a następnie elektrycznej, która jedynie tymczasowo przywróciła rytm zatokowy. Badanie echokardiograficzne wykazało umiarkowaną niedomykalność zastawki trójdzielnej i powiększoną zatokę wieńcową. Zlecono wykonanie tomografii komputerowej serca, ujawniając obecność PLSVC, do której uchodzi lewa żyła płucna górna, z przesunięciem przegrody międzyprzedsionkowej w prawo i drożnym otworem owalnym (<i>patent foramen ovale</i> – PFO). Po konsultacji kardiochirurgicznej pacjentka została zakwalifikowana do korekcji wady.WnioskiPLSVC może towarzyszyć wadom wrodzonym takim jak ASD typu 2/PFO, co ma znaczenie w leczeniu arytmii oraz korekcji wad. Powiększona zatoka wieńcowa w echokardiografii powinna budzić podejrzenie PLSVC. Obecność PLSVC jest istotna przy umieszczaniu urządzeń z centralnym dostępem żylnym, ponieważ może stanowić trudności.
Successful Management of Bilateral Subdural Hematoma: Combining Bilateral Middle Meningeal Arteries Embolization and Unilateral Burr Hole Craniostomy—A Case Report
Authors: Soetanto Gameliel Wibowo , Lilikwatil Pieter Melchias Jacob , Usman Fritz Sumantri 
Published: February 2025

Highlight:

The approach to bilateral SDH management was still tailor-made, especially in the elderly, due to the benefit of reducing intracranial pressure and the risk of increased complications and recurrent bleeding.
In cases of bilateral SDH, middle meningeal artery (MMA) embolization before surgery may increase the favorable outcome and lower the risk of SDH rebleeding.

ABSTRACT
Introduction: Subdural hematoma (SDH) is frequently seen in the elderly population. Although anticoagulant use and traumatic brain injury are recognized risk factors, the exact cause of subdural hematomas in certain cases remains unknown. Furthermore, unilateral or bilateral hemispheres may be involved in SDH, which can occur acutely or gradually. The old age group’s SDH profile, which includes several comorbidities, may complacte surgery, the gold standard for treatment. Embolization of the middle meningeal artery (MMA) may be a treatment option because it is safer and has a higher success rate in terms of improvement compared to complications. It can be done as either a standalone procedure or an adjuvant to surgery. Case: An elderly male patient experienced acute left-sided weakness that worsened over three days. Imaging revealed bilateral SDH, with symptomatic chronic SDH on the right side, asymptomatic acute SDH on the left side, and midline shift. Bilateral MMA embolization was done, followed by burr hole craniostomy, which resulted in clinical and radiological improvement throughout a three-month post-intervention period. Conclusion:MMA embolization can improve clinical outcomes and prevent recurrent bleeding, which makes it a potential treatment option for severe symptomatic SDH, especially in patients with comorbidities.
Breviario de términos jurídicos para estudiantes universitarios no juristas
Authors: Acosta Penco Teresa 
Published: February 2025

Segunda edición, completada y actualizada por Teresa Acosta Penco.
Autores:
Teresa Acosta Penco, Lucía Alarcón Sotomayor, Antonio Bueno Armijo, Manuel Izquierdo Carrasco, Nuria Magaldi Mendaña y Manuel A. Rodríguez Portugués
Innovative methods for dissemination of research results during a Pandemic: A Game- Changing Approach in the ORCHESTRA project
Authors: Pantano D. , Davis R. J. , Vitali S. , Carrara E. , Gorska A. , Carra L. , Niesters H. G.M. , Agodi A. , Kochs E. F. , Niedźwiedzka-Rystwej P. , Krause T. G. , Jahn D. , Tacconelli E. , Friedrich A. W. 
Published: February 2025

Abstract

Background
Effective communication is crucial during pandemics to mitigate fear and promote acceptance of public health measures. However, the COVID-19 pandemic revealed significant challenges, including an overwhelming volume of scientific information, poor quality control, and a rise in false or misleading data. Peer-reviewed publications often faced criticism for fast-tracked review processes, with pre-prints contributing to an increased retraction rate. These issues undermined public trust and the implementation of evidence-based measures.
Methods
The Horizon2020 ORCHESTRA project developed the COVID-19 Global Guidance Group (CGGG), an external expert evaluation mechanism, to critically assess scientific publications and ensure the dissemination of accurate and relevant findings. The CGGG employed the Delphi method to systematically achieve expert consensus on the evaluation of research outputs. Findings were tailored for stakeholders such as policymakers, the scientific community, and the general public.
Results
The CGGG evaluated over 100 peer-reviewed publications, achieving an average impact factor of 8.7 and ensuring the dissemination of evidence-based findings. The use of the Delphi method enhanced the rigor of the evaluation process and improved the targeting of communication strategies, addressing gaps in public and scientific engagement during the pandemic.
Conclusions
The ORCHESTRA project’s experience highlights the value of external expert evaluation, supported by consensus-building approaches like the Delphi method, in scientific dissemination during crises. Broader adoption of similar mechanisms could improve the integrity and effectiveness of communication strategies, bolstering public trust and evidence-based policymaking in future health emergencies.
The relationship of cytomegalovirus with physical functioning and health-related quality of life in older adults
Authors: Kirkham Frances A , Shwe Phu Sabei , Mensah Ekow , Rajkumar C 
Published: February 2025

Abstract

Methods
210 participants in the south of England with mean age 69.8 years underwent demographic and medical questionnaires, measures of body composition (bioimpedance analysis), handgrip strength and the short form 36 item survey of quality of life (SF36). All participants had peripheral venepuncture to assess CMV serology and inflammatory markers. Measures of sarcopenia were calculated using European Working Group definitions.
Results
51.7% of participants were positive for CMV IgG. There were no significant differences between CMV positive and negative groups in age, gender, measures of sarcopenia or inflammatory markers. CMV positive groups had lower scores in all domains of the SF36, with significantly lower physical function score (88.7 vs 81.3, p = 0.003) as well as total score, limitations due to physical health, energy/fatigue, social functioning and pain. Physical functioning score was significantly correlated with measures of sarcopenia including handgrip strength (r = 0.155 p = 0.026) and appendicular skeletal muscle mass index (r = 0.201, p = 0.005). On linear regression, CMV status was significantly associated with SF36 physical function score (p = 0.004) after adjustment for age, gender, BMI, CRP and handgrip strength.
Conclusion
CMV positivity is significantly associated with physical function and health-related quality of life in older adults, although its direct relationship to sarcopenia is yet to be fully ascertained.
Photo Ionic gelatin power source by Ion-gradient and photo redox pairs synchronization
Authors: Wang Fan , Lu Zelin , Hang Xinxin , Zhao Zinan , Cheng Long , Zeng Yu , Li Bixuan , Tian Menghan , Liu Baolei , Zhu Hongyan , Wang Zhiying , Ma Menghao , Wang Jinliang , Gong Yongji , Zhong Xiaolan , Wang Yang , Chang Lingqian 
Published: February 2025

Abstract

Flexible photoelectric power sources are promising to power Internet-of-things sensors, freeing the limitations of wired power sources or batteries and enabling bio-integrated devices. Traditional photo power sources have to be integrated with energy storage modules since photovoltaic materials have an order of nanosecond lifetime for photogenerated charge carriers. Obtaining flexible, biocompatible power sources that can perform light harvesting and store energy simultaneously is still challenging. In this paper, inspired by natural ion gradient diffusion in organisms, we develop a novel photoelectric conversion mechanism that synchronizes the mechanism of photoinduced ion gradient diffusion and photo-REDOX pairs (I-PR), offering an ion-hydrogel-based flexible photo power source. Through the photochemical process of ammonium molybdate, the electric potential of the device is regulated by the altered ion gradient of gelatin hydrogel and the REDOX (/) pairs, to generate energy. In comparison with photovoltaic materials-based photo power sources, the carrier life is times longer than that of commercial solar cell, we can still obtain a considerable output power for milliseconds to thousands of seconds after the termination of the initial illumination. Additionally, reaping the benefits from I-PR, the open-circuit potential is independent of the power sources’ volume. The flexible hydrogel droplets support the fabrication of arbitrary and millimetre-scale structures. A single photo power source can generate an open-circuit potential of ~ 250 mV, even with a 20-fold reduction in volume to ~10 mm3. The reversible hydrogel network allows for the recovery and re-manufacturing of the photo power source, with a 61% potential retention rate after two cycles of recycling and re-manufacturing. We further demonstrate the flexible photo power source can stimulate the activity of biological tissue cells, regulate the expression of proliferative genes on demand and facilitate tissue wound repair. This ionic hydrogel opens a new avenue for flexible, battery-free, biocompatible devices.
Metabolomic Signatures in Adults with Metabolic Syndrome Indicate Preclinical Disruptions in Pathways Associated with High-Density Lipoprotein Cholesterol, Sugar Alcohols
Authors: Lewis K. A. , Stroebel Benjamin M. , Kanaya Alka M. , Aouizerat Bradley , Longoria Kayla D. , Flowers Elena 
Published: February 2025

Abstract

Background
Metabolic syndrome is a pressing public health issue and risk factor for the development of type 2 diabetes (T2D) and cardiovascular disease (CVD), yet clinical practice is lacking in biomarkers that represent pre-clinical perturbations of the heterogenous subtypes of risk. This study aimed to characterize the baseline metabolome in relation to known clinical characteristics of risk in a sample of obese adults.
Methods
Untargeted metabolome data from N = 126 plasma samples with baseline data from a previously completed study including obese adults with metabolic syndrome. Metabolites were acquired using validated liquid chromatography mass spectrometry methods with 15–25 internal standards quantified by peak heights. Pearson’s correlations were used to determine relationships between baseline metabolites, sample characteristics (e.g., age, body mass index (BMI)), and atherosclerotic clinical characteristics (e.g., high-density lipoprotein cholesterol (HDL), low-density lipoprotein cholesterol (LDL), triglycerides), adjusting for multiple comparisons using the Benjamini-Hochberg False Discovery Rate (FDR) method. Differences in metabolite levels between clinical classifications of dysglycemia (e.g., normal, prediabetes, diabetes) at baseline were assessed using ANOVA and adjusted for multiple comparisons and adjusted for covariates.
Results
The sample consisted primarily of female (74%) participants, predominantly white (70%), with an average age of 56 years. After FDR adjustment, two baseline metabolites were significantly associated with age (xylose, threitol), two with BMI (shikimic acid, propane-1,3-diol), one with LDL (tocopherol-alpha), and 42 with HDL cholesterol. Three metabolites were significantly associated with fasting blood glucose (FBG) levels at baseline (glucose, gluconic acid lactone, pelargonic acid).
Conclusions
This study identified novel metabolite associations with known markers of T2D and CVD risk. Specific metabolites, such as alpha-tocopherol, branched-chain amino acids (BCAAs), and sugar-derived metabolites like mannose and xylose, were significantly associated with age, BMI, lipid profiles, and glucose measures. Although most sample participants had normal HDL cholesterol at baseline, 42 metabolites including branched chain amino acids were significantly associated with HDL, suggesting pre-clinical perturbations in biological pathways associated with both diabetes and cardiovascular comorbidities. Metabolomic signatures specific to prediabetes and metabolic syndrome can enhance risk stratification and enable targeted prevention strategies for T2D. Longitudinal studies are needed to understand how these associations change over time in at-risk individuals compared with controls.
Malaria transmission risk in the city of Accra, Ghana: vector behavior and distribution
Authors: Sabtiu Abdul Rahim Mohammed , Sr Isaac Kwame , Mfum Christopher Owusu-Asenso , Akuamoah-Boateng Yaw , Doe Richard Tettey , Boadu Emmanuel Nana , Azumah Judith Dzifa , Eyeson Nana Aba , Abdulai Anisa , Amoateng Godfred , Attah Simon Kwaku , Aboagye-Antwi Fred , Afrane Yaw Asare 
Published: February 2025

Abstract

Background: Urban malaria transmission in sub-Saharan Africa is often underestimated, emphasizing the need for research on vector distribution, abundance, behavior, and infectivity in cities. Since 2003, urban malaria transmission has intensified. Monitoring Anophelespopulations is crucial for developing effective interventions. This study examined the biting and resting habits, distribution, abundance, and Plasmodiuminfection of malaria vectors in Accra.
Methods: Adult malaria vectors were collected using human landing catch (HLC) and Prokopack aspiration (PPK) at ten sites in Accra, categorized into five groups: sites with Irrigated Urban Farming (IUF), Lower Socioeconomic Status (LS), Middle Socioeconomic Status (MS), High Socioeconomic Status (HS), and Peri-urban (PU) areas. Biting patterns and entomological transmission indices of An. gambiae s.l. were assessed, Molecular methods were used to detect sporozoite infection, bloodmeal sources, vector species, and insecticide resistant mutation genes.
Results: A total of 41,747 mosquitoes were collected. Of these, 95.49% (39,863/41,747) were host-seeking collected through human landing catch (HLC), consisting of Anopheles (52.54%, 20,945/39,863), Culex(42.00%, 16,742/39,863), Aedes (3.74%, 1,491/39,863), and Mansonia (1.72%, 685/39,863). The remaining 4.51% (1,884/41,747) were resting mosquitoes collected using a Procopack aspirator, comprising Anopheles (31.26%, 589), Culex (57.21%, 1,078), and Aedes (11.52%, 217). Overall, the irrigated urban farming (IUF) site category recorded the highest abundance of An. gambiae s.l. (48.63%, 10,466/21,520), followed by the peri-urban (PU) site category (18.06%, 3,887/21,520), high socioeconomic (HS) site category (16.42%, 3,533/21,520), middle socioeconomic (MS) site category (13.74%, 2,956/21,520), and low socioeconomic (LS) site category (3.15%, 678/21,520) in both HLC and Procopack collections.
Significantly higher mosquito biting activity was observed during the late evening (LE), the classical mosquito biting time, in both the rainy (71.45%, 11,337/15,865) and dry (72.21%, 3,658/5,066) seasons. Indoor An. gambiae s.l. had higher sporozoite infectivity (70.64%, 77/109) than outdoor mosquitoes (29.35%, 32/109) (χ² = 6.78, P = 0.009). Tuba from the IUF site had the highest sporozoite infectivity (32.11%, 35/109), with higher indoor (24.77%, 27/109) than outdoor (7.34%, 8/109) rates.
Conclusion: Anopheles gambiae s.l. drives urban malaria transmission in Accra, with high human bloodmeal indices and sporozoite infectivity, especially indoors. Urban agriculture promotes vector proliferation. Targeted indoor control and management of breeding sites in IUF areas are essential to reduce transmission.