bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reversible Double CH Bond Activation of Linear and Cyclic Ethers To Form Iridium Carbenes
Authors: Valpuesta Jose E. V. , Álvarez Eleuterio , López‐Serrano Joaquín , Maya Celia , Carmona Ernesto 
Published: September 2012

AbstractThe double CH bond activation of a series of linear and cyclic ethers by the iridium complex [Tptol′Ir(C6H5)(N2)] (2⋅N2), which features a cyclometalated hydrotris(3‐p‐tolylpyrazol‐1‐yl)borate ligand (Tptol′) coordinated in a κ4‐N,N′,N′′,C manner, has been studied. Two methyl ethers, namely, Me2O and MeOtBu, along with diethyl ether and the cyclic ethers tetrahydrofuran, tetrahydropyran (THP), and 1,4‐dioxane have been investigated with formation in every case of the corresponding hydride carbene complexes 3–8, which are stabilized by κ4‐coordination of the ancillary Tptol′ ligand. Five of the compounds have been structurally authenticated by X‐ray crystallography. A remarkable feature of these rearrangements is the reversibility of the double CH bond activation of Me2O, MeOtBu, Et2O, and THP. This has permitted catalytic deuterium incorporation into the methyl groups of the two methyl ethers, although in a rather inefficient manner (for synthetic purposes). Although possible in all cases, CC coupling by migratory insertion of the carbene into the IrC σ bond of the metalated linkage has only been observed for complex 8 that contains a cyclic carbene that results from α,α‐CH activation of 1,4‐dioxane. Computational studies on the formation of iridium carbenes are also reported, which show a role for metalated Tp ligands in the double CH activation and account for the reversibility of the reaction in terms of the relative stability of the reagents and the products of the reaction.
Graphite Oxides: Effects of Permanganate and Chlorate Oxidants on the Oxygen Composition
Authors: Chua Chun Kiang , Sofer Zdeněk , Pumera Martin 
Published: September 2012

AbstractResearch on graphene materials has refocused on graphite oxides (GOs) in recent years. The fabrication of GO is commonly accomplished by using concentrated sulfuric acid in conjunction with: a) fuming nitric acid and KClO3 oxidant (Staudenmaier); b) concentrated nitric acid and KClO3 oxidant (Hofmann); c) sodium nitrate for in situ production of nitric acid in the presence of KMnO4 (Hummers); or d) concentrated phosphoric acid with KMnO4 (Tour). These methods have been used interchangeably in the graphene community, since the properties of GOs produced by these different methods were assumed as almost similar. In light of the wide applicability of GOs in nanotechnology applications, in which presence of certain oxygen functional groups are specifically important, the qualities and functionalities of the GOs produced by using these four different methods, side‐by‐side, was investigated. The structural characterizations of the GOs would be probed by using high resolution X‐ray photoelectron spectroscopy, nuclear magnetic resonance, Fourier transform infrared spectroscopy, and Raman spectroscopy. Further electrochemical applicability would be evaluated by using electrochemical impedance spectroscopy and cyclic voltammetry techniques. Our analyses highlighted that the oxidation methods based on permanganate oxidant (Hummers and Tour methods) gave GOs with lower heterogeneous electron‐transfer rates and a higher amount of carbonyl and carboxyl functionalities compared with when using chlorate oxidant (Staudenmaier and Hofmann methods). These observations indicated large disparities between the GOs obtained from different oxidation methods. Such insights would provide fundamental knowledge for fine tuning GO for future applications.
ChemInform Abstract: Effect of the Framework Flexibility on the Centricities in Centrosymmetric In2Zn(SeO3)4 and Noncentrosymmetric Ga2Zn(TeO3)4.
Authors: Lee Dong Woo , Bak Dan‐bee , Kim Saet Byeol , Kim Jiwon , Ok Kang Min 
Published: September 2012

AbstractCrystals of In2Zn(SeO3)4 (I) and Ga2Zn(TeO3)4 (II) are prepared by solid state reaction of ZnO, In2O3 or Ga2O3, and SeO2 or TeO2 (silica tubes, 600—700 °C, 48 h).
ChemInform Abstract: Crystal Structure and Magnetic Properties of NaCuII [(CuII3O)(PO4)2Cl].
Authors: Jin Teng‐Teng , Liu Wei , Chen Shuang , Prots Yurii , Schnelle Walter , Zhao Jing‐Tai , Kniep Ruediger , Hoffmann Stefan 
Published: September 2012

AbstractThe new title compound is synthesized from a mixture of NH4H2PO4, NaCl, and CuCl2 (alumina crucible, 727 K, 2 d) and characterized by single crystal XRD and magnetic measurements.
ChemInform Abstract: Effect of Structural Packing on the Luminescence Properties in Tungsten Bronze Compounds M2KNb5O15 (M: Ca, Sr, Ba).
Authors: Yin Xin , Shi Liu , Wei Ang , Wan Dongyun , Wang Yaoming , Huang Fuqiang 
Published: September 2012

AbstractWhereas Ca2KNb5O15 exhibits host luminescence at 460 nm when excited at 269 nm, Sr2KNb5O15 and Ba2KNb5O15 do not show host luminescence.
ChemInform Abstract: Freeze‐Drying Synthesis of Li3V2(PO4)3/C Cathode Material for Lithium‐Ion Batteries.
Authors: Qiao Y. Q. , Wang X. L. , Mai Y. J. , Xia X. H. , Zhang J. , Gu C. D. , Tu J. P. 
Published: September 2012

AbstractThe title cathode material is prepared by freeze‐drying of an aqueous solution containing NH4VO3, LiOH, and H3PO4 (‐53 °C, 48 h) followed by calcination of the obtained precursor together with polystyrene spheres as the carbon source (Ar flow, 750 °C, 8 h).
ChemInform Abstract: Effects of Large Halides on the Structures of Lanthanide(III) and Plutonium(III) Borates.
Authors: Polinski Matthew J. , Wang Shuao , Cross Justin N. , Alekseev Evgeny V. , Depmeier Wulf , Albrecht‐Schmitt Thomas E. 
Published: September 2012

AbstractAs revealed by single crystal XRD compounds (III) and (VII) crystallize in the space group P21/n with Z = 4.
ChemInform Abstract: Syntheses, Crystal Structures and Characterizations of New Vanadium Arsenites and Arsenates.
Authors: Liu Jun‐Hui , He Zhang‐Zhen , Kong Fang , Xu Xiang , Sun Chuan‐Fu , Mao Jiang‐Gao 
Published: September 2012

AbstractThe structures of (III), (IV), (VII), and (VIII) are determined by single crystal XRD.
ChemInform Abstract: Synthesis of Mixed‐Valent α‐ and β‐NaFe2O3 Polymorphs under Controlled Partial Oxygen Pressure.
Authors: Bruno Shaun R. , Blakely Colin K. , Poltavets Viktor V. 
Published: September 2012

AbstractThe title polymorphs are synthesized from stoichiometric mixtures of α‐NaFeO2, α‐Fe2O3, and Fe metal under controlled oxygen partial pressure (alumina boats in a closed quartz tube, 850 °C, 48—72 h).
ChemInform Abstract: Visible Light Photoredox Organocatalysis: A Fully Transition Metal‐Free Direct Asymmetric α‐Alkylation of Aldehydes.
Authors: Fidaly Kassim , Ceballos Claire , Falguieres Annie , Veitia Maite Sylla‐Iyarreta , Guy Alain , Ferroud Clotilde 
Published: September 2012

AbstractA combination of photoredox catalyst with chiral imidazolidinone organocatalyst is used for the asymmetric α‐alkylation of aldehydes (II) with bromide (I).
ChemInform Abstract: Cine Substitution of Arenes Using the Aryl Carbamate as a Removable Directing Group.
Authors: Mesganaw Tehetena , Nathel Noah F. Fine , Garg Neil K. 
Published: September 2012

AbstractArylcarbamates undergo cine‐substitution reactions via ortho‐metallation and functionalization to afford ortho‐substituted products.
ChemInform Abstract: Bi(OTf)3‐Catalyzed Cycloisomerization of Aryl‐Allenes.
Authors: Lemiere Gilles , Cacciuttolo Bastien , Belhassen Emilie , Duncah Elisabet 
Published: September 2012

AbstractCyclohydroarylation or tandem intramolecular cycloaddition reactions produce different types of polycycles.
ChemInform Abstract: Gold(I)‐Catalyzed Regioselective Inter‐/Intramolecular Addition Cascade of Di‐ and Triynes for Direct Construction of Substituted Naphthalenes.
Authors: Naoe Saori , Suzuki Yamato , Hirano Kimio , Inaba Yusuke , Oishi Shinya , Fujii Nobutaka , Ohno Hiroaki 
Published: September 2012

AbstractThe method provides a new approach to 1,3‐disubstituted naphthalenes, disubstituted chrysenes, and related compounds.
ChemInform Abstract: An Excellent Dual Recycling Strategy for the Hypervalent Iodine/Nitroxyl Radical Mediated Selective Oxidation of Alcohols to Aldehydes and Ketones.
Authors: Dohi Toshifumi , Fukushima Kei‐ichiro , Kamitanaka Tohru , Morimoto Koji , Takenaga Naoko , Kita Yasuyuki 
Published: September 2012

AbstractAn adamantane‐derived hypervalent iodine reagent is an efficient oxidant for the conversion of primary and secondary alcohols.
ChemInform Abstract: Terminal Alkyne Homocoupling Reactions Catalyzed by an Efficient and Recyclable Polymer‐Supported Copper Catalyst at Room Temperature under Solvent‐Free Conditions.
Authors: He Ying , Cai Chun 
Published: September 2012

AbstractBoth aromatic and aliphatic terminal alkynes undergo the homocoupling reaction within only 10‐20 minutes to give the corresponding 1,4‐disubstituted 1,3‐diynes in excellent to high yields.
ChemInform Abstract: Thiopseudourea Ligated Palladium Complexes: Synthesis, Characterization and Application as Catalysts for Suzuki—Miyaura, Sonogashira, Heck and Hiyama Reactions.
Authors: Srinivas Keesara , Srinivas Pottabathula , Prathima Parvathaneni Sai , Balaswamy Kodicherla , Sridhar Balsubramanian , Rao Mandapati Mohan 
Published: September 2012

AbstractSix palladium complexes of type (I) are prepared in 4 steps from commercially available benzoyl chlorides.
ChemInform Abstract: Dehydrogenative Amide Synthesis from Alcohol and Amine Catalyzed by Hydrotalcite‐Supported Gold Nanoparticles.
Authors: Zhu Jiangling , Zhang Yan , Shi Feng , Deng Youquan 
Published: September 2012

AbstractWith exception of benzyl amine (IIa), only cyclic amines are found to be efficient substrates in the amidation process.
ChemInform Abstract: Highly Atom Economical Uncatalyzed and I2‐Catalyzed Silylation of Phenols, Alcohols and Carbohydrates, Using HMDS under Solvent‐Free Reaction Conditions (SFRC).
Authors: Jereb Marjan 
Published: September 2012

AbstractThe environmentally friendly method is performed strictly without a solvent, in the presence of air, and using a small excess of Tms2NH to give the crude products with high purity.
ChemInform Abstract: Synthesis of Amines from Alcohols in a Nonepimerizing One‐Pot Sequence — Synthesis of Bioactive Compounds: Cinacalcet and Dexoxadrol.
Authors: Guerin Claire , Bellosta Veronique , Guillamot Gerard , Cossy Janine 
Published: September 2012

AbstractThe present method proceeds without epimerization of enantioenriched amines or alcohols.
ChemInform Abstract: Preparation of Modified Peptides: Direct Conversion of α‐Amino Acids into β‐Amino Aldehydes.
Authors: Saavedra Carlos J. , Boto Alicia , Hernandez Rosendo 
Published: September 2012

AbstractThe present method is applied to preparation of small peptide derivatives with β‐aldehyde moieties which in turn are precursors of peptides possessing a γ‐alcohol unit.
ChemInform Abstract: Enantioselective Diels—Alder Reaction of α‐(Acylthio)acroleins: A New Entry to Sulfur‐Containing Chiral Quaternary Carbons.
Authors: Sakakura Akira , Yamada Hiroki , Ishihara Kazuaki 
Published: September 2012

AbstractUnfortunately, coupling of the acrolein (Ie) with cyclopentadiene gives racemic products.
ChemInform Abstract: Nickel‐Catalyzed Regio‐ and Stereoselective Reductive Coupling Between Methylenecyclopropanes, Aldehydes, and Triethylborane with Retention of the Cyclopropane Ring.
Authors: Ogata Kenichi , Shimada Daisuke , Fukuzawa Shin‐ichi 
Published: September 2012

AbstractThe title reaction generates cyclopropane derivatives with a quaternary stereocenter in a stereoselective manner.
ChemInform Abstract: Tandem Nucleophilic Addition/Fragmentation of Vinylogous Acyl Nonaflates for the Synthesis of Functionalized Alkynes, with New Mechanistic Insight.
Authors: Batsomboon Paratchata , Gold Brian A. , Alabugin Igor V. , Dudley Gregory B. 
Published: September 2012

AbstractThe utility of nonaflates (III) in title reactions to provide alkyne‐tethered ketones and β‐ketophosphonates is demonstrated.
ChemInform Abstract: Magnetically Separable Cu‐Carboxylate MOF Catalyst for the Henry Reaction.
Authors: Arai Takayoshi , Kawasaki Nao , Kanoh Hirofumi 
Published: September 2012

AbstractThe metal‐organic framework is synthesized and successfully employed as catalyst in the cross‐coupling reaction of phenylacetylene with 2‐oxazolidinone.
ChemInform Abstract: Direct Reductive Amination of Aldehydes Using Lithium—Arene (cat.) as Reducing System: A Simple One‐Pot Procedure for the Synthesis of Secondary Amines.
Authors: Nador Fabiana , Moglie Yanina , Ciolino Andres , Pierini Adriana , Dorn Viviana , Yus Miguel , Alonso Francisco , Radivoy Gabriel 
Published: September 2012

AbstractMain products are the expected secondary amines or analogous imines for substrates having electron‐withdrawing groups.
ChemInform Abstract: Asymmetric Transfer Hydrogenation of Ketones Catalyzed by Nickel Complex with New PNO‐Type Ligands.
Authors: Dong Zhen Rong , Li Yan Yun , Yu Shen Luan , Sun Guo Song , Gao Jing Xing 
Published: September 2012

AbstractModerate to good enantioselectivities can be obtained for aromatic ketone substrates.
ChemInform Abstract: Graphene Oxide as an Acid Catalyst for the Room Temperature Ring Opening of Epoxides.
Authors: Dhakshinamoorthy Amarajothi , Alvaro Mercedes , Concepcion Patricia , Fornes Vicente , Garcia Hermenegildo 
Published: September 2012

AbstractA simple and general procedure for the title reaction is developed by using a highly efficient and easily recoverable and reusable catalyst for additional runs before deactivation.
ChemInform Abstract: Preparation of Chiral 3‐Arylpyrrolidines via the Enantioselective 1,4‐Addition of Arylboronic Acids to Fumaric Esters Catalyzed by Rh(I)/Chiral Diene Complexes.
Authors: Chung Yu‐Chiang , Janmanchi Damodar , Wu Hsyueh‐Liang 
Published: September 2012

AbstractA wide range of arylboronic acids is subjected to the reaction with diester (I).
ChemInform Abstract: SN1‐Type Substitution Reactions of N‐Protected β‐Hydroxytyrosine Esters: Stereoselective Synthesis of β‐Aryl and β‐Alkyltyrosines.
Authors: Wilcke David , Herdtweck Eberhardt , Bach Thorsten 
Published: September 2012

AbstractStereochemistry of desired aryl‐and β‐alkyltyrosines is strongly influenced by the choice of protecting and ester groups of starting hydroxytyrosine esters.
ChemInform Abstract: Highly Enantio‐ and Diastereoselective Vinylogous Aldol Reaction by LiCl‐Assisted BINOL—Titanium Species.
Authors: Wang Guowei , Wang Baomin , Qi Shuai , Zhao Jinfeng , Zhou Yuhan , Qu Jingping 
Published: September 2012

AbstractThe reaction is applied to a wide range of aromatic, olefinic and aliphatic aldehydes to prepare the target products in high yields and nearly complete enantioselectivities.
ChemInform Abstract: Supported Au Nanoparticles as Efficient Catalysts for Aerobic Homocoupling of Phenylboronic Acid.
Authors: Wang Liang , Zhang Wei , Su Dang Sheng , Meng Xiangju , Xiao Feng‐Shou 
Published: September 2012

AbstractA highly active and easily recyclable catalyst is prepared for the title synthesis.
ChemInform Abstract: Organocatalytic Asymmetric Synthesis of Trifluoromethyl‐Substituted Diarylpyrrolines: Enantioselective Conjugate Cyanation of β‐Aryl‐β‐trifluoromethyl‐disubstituted Enones.
Authors: Kawai Hiroyuki , Okusu Satoshi , Tokunaga Etsuko , Sato Hiroyasu , Shiro Motoo , Shibata Norio 
Published: September 2012

AbstractThe simple title synthesis is reported for the first time.
ChemInform Abstract: An Active and Selective Heterogeneous Catalytic System for Michael Addition.
Authors: Keipour Hoda , Khalilzadeh Mohammad A. , Hosseini Abolfazl , Pilevar Afsaneh , Zareyee Daryoush 
Published: September 2012

AbstractIt is demonstrated that the exceedingly strong base KF on clinoptilotite is highly efficient for the selective 1,4‐Michael addition of different donors to chalcones to give the adducts in excellent yields.
ChemInform Abstract: Synthesis of 1,1‐Diarylethylenes via Efficient Iron/Copper Co‐Catalyzed Coupling of 1‐Arylvinyl Halides with Grignard Reagents.
Authors: Hamze Abdallah , Brion Jean‐Daniel , Alami Mouad 
Published: September 2012

AbstractA wide range of biologically valuable title compounds is prepared.
ChemInform Abstract: Feeding the Heck Reaction with Alcohol: One‐Pot Synthesis of Stilbenes from Aryl Alcohols and Bromides.
Authors: Colbon Paul , Barnard Jonathan H. , Purdie Mark , Mulholland Keith , Kozhevnikov Ivan , Xiao Jianliang 
Published: September 2012

AbstractThe reaction proceeds via selective dehydration of alcohols to styrenes followed by a Pd‐catalyzed Heck arylation to afford a variety of functionalized stilbenes in one‐pot manner.
ChemInform Abstract: Tandem Decarboxylative Allylation and Fragmentation of Allyl Benzocyclobutenyl Carbonates: Access to ortho‐Functionalized Aryls from Aryl Bromides.
Authors: Rosa David , Chtchemelinine Andrei , Orellana Arturo 
Published: September 2012

AbstractBenzocyclobutenols (IV) and (VI) undergo Pd‐catalyzed decarboxylative allylation and selective β‐elimination leading to ortho‐substituted arenes (V) and (VII), generally in good yields.
ChemInform Abstract: A Convenient and Efficient Synthesis of 2‐Acetyl‐5,8‐dimethoxy‐1,4‐naphthoquinone.
Authors: Cui Jia‐hua , Zhou Wen , Li Shao‐shun 
Published: September 2012

AbstractCompound (VI), prepared by a route suitable for large‐scale production, exhibits cytotoxicity and inhibition of DNA topoisomerase‐I.
ChemInform Abstract: Preparation of (E)‐4‐Aryl‐1,1,1‐trifluoro‐3‐tosylbut‐3‐en‐2‐ones as Fluorinated Building Blocks and Their Application in Ready and Highly Stereoselective Routes to trans‐2,3‐Dihydrofurans Substituted with Trifluoromethyl and Sulfonyl Groups.
Authors: Yu Haigang , Han Jing , Chen Jie , Deng Hongmei , Shao Min , Zhang Hui , Cao Weiguo 
Published: September 2012

AbstractThe arsonium‐ylide assisted ring‐closure reaction proceeds with excellent diastereoselectivity, leading to exclusive formation of the thermodynamical stable trans‐isomers.
ChemInform Abstract: Electrophilic Iodo‐Mediated Cyclization in PEG under Microwave Irradiation: Easy Access to Highly Functionalized Furans and Pyrroles.
Authors: Spina Rosella , Colacino Evelina , Gabriele Bartolo , Salerno Giuseppe , Martinez Jean , Lamaty Frederic 
Published: September 2012

AbstractMicrowave‐assisted iodocyclization of diols (I) or amino alcohols (III) is achieved in the presence of NaHCO3.
ChemInform Abstract: Direct Arylation of Dithienylperfluorocyclopentenes via Palladium‐Catalyzed C—H Bond Activation: A Simpler Access to Photoswitches.
Authors: Beydoun Kassem , Boixel Julien , Guerchais Veronique , Doucet Henri 
Published: September 2012

AbstractThe use of cyclopentyl methyl ether as the solvent is found to be crucial to avoid decomposition of the reactants and the products.
ChemInform Abstract: Copper‐Catalyzed Clauson—Kass Pyrroles Synthesis in Aqueous Media.
Authors: Deng Hong‐Juan , Fang Yu‐Jing , Chen Gao‐Wei , Liu Miao‐Chang , Wu Hua‐Yue , Chen Jiu‐Xi 
Published: September 2012

AbstractCopper‐catalyzed Clauson—Kass reaction of dimethoxytetrahydrofuran (I) with aromatic amines provides a convenient and efficient access towards N‐arylpyrroles, e.g. (III).
ChemInform Abstract: Catalytic Asymmetric Sulfenylation of Unprotected 3‐Substituted Oxindoles.
Authors: Cai Yunfei , Li Jun , Chen Weiliang , Xie Mingsheng , Liu Xiaohua , Lin Lili , Feng Xiaoming 
Published: September 2012

AbstractThe catalytic system is used to prepare 3‐phenylthiooxindoles with aromatic, benzylic or aliphatic substituents at the 3‐position and different substitution at the indole benzene ring.
ChemInform Abstract: An N‐Heterocyclic Carbene/Lewis Acid Strategy for the Stereoselective Synthesis of Spirooxindole Lactones.
Authors: Dugal‐Tessier Julien , O'Bryan Elizabeth A. , Schroeder Thomas B. H. , Cohen Daniel T. , Scheidt Karl A. 
Published: September 2012

AbstractIn the reaction of β‐aryl substituted enals the addition of LiCl enhances the level of entantioselectivity.
ChemInform Abstract: Catalytic Conjugate Addition of Indole to α,β‐Unsaturated Ketones by Co(ClO4)2·6H2O/Bis‐Schiff Base Complexes.
Authors: Hui Yong Hai , Chen Chun Mei , Xie Zheng Feng 
Published: September 2012

AbstractThe catalytic system is highly efficient in the preparation of 3‐substituted indole derivatives including complex triazole segments.
ChemInform Abstract: A General Method for the Synthesis of 5H‐Benzo[b]‐, Carbazolo[2,3‐b]‐ and Indolo[2,3‐b]carbazole Derivatives via Copper(II) Triflate‐Catalyzed Heteroannulation.
Authors: Prakash K. S. , Nagarajan Rajagopal 
Published: September 2012

AbstractA wide range of title compounds via is constructed heteroannulation which is best catalyzed by Cu(OTf)2.
ChemInform Abstract: Absolute Asymmetric Synthesis of Tertiary α‐Amino Acids.
Authors: Mai Thi Thoa , Branca Mathieu , Gori Didier , Guillot Regis , Kouklovsky Cyrille , Alezra Valerie 
Published: September 2012

AbstractThe first example for the use of the frozen‐chirality approach for the synthesis of biologically interesting compounds, e.g. amino ester (VIII), is presented.
ChemInform Abstract: The First One‐Pot, Solvent‐Free, Microwave‐Accelerated, Three‐Component Synthesis of Spirothiazolidin‐4‐ones via Staudinger/Aza‐Wittig Coupling/Cyclization.
Authors: Ponnuswamy Alagusundaram , Shanmugavelan Poovan , Nagarajan Sangaraiah , Sathishkumar Murugan 
Published: September 2012

AbstractAn efficient, rapid, and environmentally benign title synthesis of the compounds (IV) is developed.
ChemInform Abstract: One Pot “Click” Reaction: CuII—Hydrotalcite Catalyzed Tandem Synthesis of β‐Hydroxy Triazoles via Regioselective Opening of Epoxide Followed by [3 + 2] Cycloaddition.
Authors: Prasad Avvari N. , Thirupathi Boningari , Raju Gangadhara , Srinivas Rapelli , Reddy Benjaram M. 
Published: September 2012

AbstractThe title three‐component reaction is performed in water at ambient temperature without any additives.
ChemInform Abstract: Synthesis and in vitro Activity of Novel 2‐(Benzylthio)‐4‐chloro‐5‐(1,3,4‐oxadiazol‐2‐yl)benzenesulfonamide Derivatives.
Authors: Brozewicz Kamil , Slawinski Jaroslaw 
Published: September 2012

Abstract10 Title compounds of type (IX) are prepared and evaluated for their in vitro activities against the full NCI‐60 cell line panel.
ChemInform Abstract: Synthesis of Isocoumarin Derivatives via the Copper‐Catalyzed Tandem Sequential Cyclization of 2‐Halo‐N‐phenyl Benzamides and Acyclic 1,3‐Diketones.
Authors: Kavala Veerababurao , Wang Cheng‐Chuan , Barange Deepak Kumar , Kuo Chun‐Wei , Lei Po‐Min , Yao Ching‐Fa 
Published: September 2012

AbstractThe reaction allows a rapid and efficient access to various isocoumarins.
ChemInform Abstract: Rhenium‐Catalyzed Regioselective Synthesis of Multisubstituted Pyridines from β‐Enamino Ketones and Alkynes via C—C Bond Cleavage.
Authors: Yamamoto Shun‐ichi , Okamoto Kana , Murakoso Makiko , Kuninobu Yoichiro , Takai Kazuhiko 
Published: September 2012

AbstractRe2(CO)10‐catalyzed treatment of N‐acetylated and N‐methoxycarbonylated β‐enamino ketones with alkynes allows a new and regioselective access to multisubstituted pyridines.
ChemInform Abstract: Synthesis and Structure—Activity Relationships of 1,2,4‐Triazolo[1,5‐a]pyrimidin‐7(3H)‐ones as Novel Series of Potent β Isoform Selective Phosphatidylinositol 3‐Kinase Inhibitors.
Authors: Sanchez Robert M. , et al. et al. 
Published: September 2012

AbstractNew compounds (Vb)—(Ve) are very potent inhibitors of the phosphatidylinositol 3‐kinase‐β enzyme with IC50 values of 0.001 μM or less.
ChemInform Abstract: Facile Synthesis of Novel Fluorinated Thieno[2,3‐d]pyrimidine Derivatives Containing 1,3,4‐Thiadiazole.
Authors: Song Xin Jian , Duan Zheng Chao , Shao Yu , Dong Xing Gao 
Published: September 2012

AbstractA microwave‐assisted three‐step sequence allows the synthesis of the title compounds (VI) as pharmaceutically interesting frameworks.
ChemInform Abstract: Azepine Synthesis from Alkyl Azide and Propargylic Ester via Gold Catalysis.
Authors: Liu Heng , Li Xin , Chen Zili , Hu Wen‐Xiang 
Published: September 2012

AbstractThe procedure allows a new and efficient approach to a number of polysubstituted 4,5‐dihydroazepines.