bluuebunny/crossref_metadata_2025_split huggingface dataset:
C-reactive protein promotes acute kidney injury by impairing G1/S-dependent tubular epithelium cell regeneration
Authors: Tang Ying , Huang Xiao Ru , Lv Jun , Chung Arthur Chi-Kong , Zhang Yang , Chen Jun-Zhe , Szalai Alexander J. , Xu Anping , Lan Hui Y. 
Published: November 2013

CRP (C-reactive protein) is regarded as an inflammatory biomarker in AKI (acute kidney injury), but its exact role in AKI remains unclear. Thus we sought to investigate the role of CRP in AKI. Clinically, elevated serum CRP levels were found to associate closely with increased serum creatinine and urea levels (P&lt;0.01) in patients with AKI, which then fell after recovery from AKI. To determine the role of CRP in AKI, an ischaemia/reperfusion mouse model of AKI was developed using Tg (transgenic) mice that express human CRP. Compared with the WT (wild-type) mice, CRP Tg mice developed more severe renal injury at 24 h after ischaemia as determined by significantly increased serum creatinine and tubular necrosis. This was associated with an impaired TEC (tubular epithelium cell) regeneration as shown by an over 60% reduction in PCNA+ (proliferating-cell nuclear antigen) and BrdU+ (bromodeoxyuridine) TECs in CRP Tg mice with AKI. In vitro, the addition of CRP to a human TEC line (HK-2) also largely suppressed the proliferation of TECs. The functional role of CRP in AKI was demonstrated further by the blocking of CRP binding to the FcγRII (Fcγ receptor II) with a neutralizing anti-CD32 antibody, which restored TEC proliferation and prevented AKI in CRP Tg mice. Moreover, we found that impaired G1/S transition by suppression of the phosphorylation of CDK2 (cyclin-dependent kinase 2) and expression of cyclin E may be a key mechanism by which CRP inhibits TEC regeneration during the AKI repair process. In conclusion, CRP plays a pathogenic role in AKI by inhibiting G1/S-dependent TEC regeneration. The results of the present study suggest that targeting CRP signalling may offer a new therapeutic potential for AKI.
Communication: Nuclear quadrupole moment-induced Cotton-Mouton effect in noble gas atoms
Authors: Fu Li-juan , Rizzo Antonio , Vaara Juha 
Published: November 2013

New, high-sensitivity and high-resolution spectroscopic and imaging methods may be developed by exploiting nuclear magneto-optic effects. A first-principles electronic structure formulation of nuclear electric quadrupole moment-induced Cotton-Mouton effect (NQCME) is presented for closed-shell atoms. In NQCME, aligned quadrupole moments alter the index of refraction of the medium along with and perpendicular to the direction of nuclear alignment. The roles of basis-set convergence, electron correlation, and relativistic effects are investigated for three quadrupolar noble gas isotopes: 21Ne, 83Kr, and 131Xe. The magnitude of the resulting ellipticities is predicted to be 10−4–10−6 rad/(M cm) for fully spin-polarized nuclei. These should be detectable in the Voigt setup. Particularly interesting is the case of 131Xe, in which a high degree of spin polarization can be achieved via spin-exchange optical hyperpolarization.
The Safety of Aquaflor (50% Florfenicol) Administered in Feed to Fingerling Yellow Perch
Authors: Bowker James D , Carty Dan , Bowman Molly P 
Published: November 2013

Abstract
Aquaflor is an aquaculture feed premix containing 50% florfenicol and is approved for use in more than 50 countries to control mortality in a variety of cultured fishes caused by diseases associated with infectious bacterial pathogens. As part of an effort to expand the current approval in the United States, we conducted a study to evaluate the safety of Aquaflor to Yellow Perch Perca flavescens when administered in feed at 0× (0 mg/kg), 1× (15 mg/kg), 3× (45 mg/kg), or 5× (75 mg/kg) the proposed maximum therapeutic treatment dose of 15 mg florfenicol·kg fish−1·d−1 for 20 consecutive days, 2× the proposed therapeutic treatment duration of 10 consecutive days. Fingerling Yellow Perch (7.8 ± 1.6 cm and 5.0 ± 3.4 g; mean ± SD) were stocked into flow-through test tanks at 15 fish per tank, and treatments were randomly assigned to tanks in triplicate. At the end of the 20-d exposure period, mean cumulative mortality in the 0× and 3× groups (6.7% for both) was greater than that in the 1× and 5× groups (2.2% and 0.0%, respectively); however, differences among the groups were not significant (P = 0.3741). Throughout the study, general fish behavior was characterized as normal, and fish consumed virtually all feed offered. Fish health and histology assessments revealed no signs or lesions associated with toxicity of florfenicol. In conclusion, there is an adequate margin of safety associated with administering Aquaflor-medicated feed to fingerling Yellow Perch at the proposed therapeutic treatment regimen of 15 mg florfenicol·kg fish−1·d−1 for 10 d.
The Effect of Stocking Different Ratios of Nile Tilapia Oreochromis niloticus, Striped Mullet Mugil cephalus, and Thinlip Grey Mullet Liza ramada in Polyculture Ponds on Biomass Yield, Feed Efficiency, and Production Economics
Authors: Tahoun Al-Azab , Suloma Ashraf , Hammouda Yasser , Abo-State Hanan , El-Haroun Ehab 
Published: November 2013

Abstract
A 180-d trial was done to evaluate the effect of stocking different ratios of Nile Tilapia Oreochromis niloticus, Striped Mullet Mugil cephalus, and Thinlip Grey Mullet Liza ramada on production and economic return in brackish-water ponds. The trial was conducted in twelve 3,000-m2 earthen ponds with four treatments (3 ponds/treatment): Nile Tilapia alone (100% Nile Tilapia, monoculture group [MG]); 75% Nile Tilapia and 25% Thinlip Grey Mullet (polyculture group 1 [PG1]); 75% Nile Tilapia, 12.5% Thinlip Grey Mullet, and 12.5% Striped Mullet (PG2); and 75% Nile Tilapia and 25% Striped Mullet (PG3). Fish were fed a commercial diet containing 25% crude protein twice per day. The efficiency of feed utilization was determined in terms of feed conversion ratio (FCR; feed intake/weight gain). Polyculture group 3 had the best FCR, whereas the FCR results did not differ significantly among the MG, PG1, and PG2 treatments. In addition, PG3 had the highest total yield (3,350.3 kg/pond), followed in descending order by PG2 (3,234.4 kg/pond), PG1 (3,078.4 kg/pond), and MG (2,856.3 kg/pond). The PG3 treatment achieved the highest net financial return, followed by PG2, PG1, and MG. This study indicates that tilapia–mullet polyculture may improve the efficiency with which natural food resources are used within the system, resulting in better environmental quality, system sustainability, feed utilization, and net financial return.
Measuring credit capacity on Danish farms using DEA
Authors: Friis Pedersen Michael , Vesterlund Olsen Jakob 
Published: November 2013

Purpose
– The purpose of this paper is to introduce a novel measure of access to credit suited to estimate the relative change in credit reserves.

Design/methodology/approach
– A debt possibility frontier is estimated using data envelopment analysis and the Malmquist index is calculated. The Malmquist index is redubbed the Debt Development index and decomposed into “change in debt capacity” and “change in debt capacity utilization”. Bootstrapping is applied for statistical inference. The method is applied to an unbalanced panel of 92,000 Danish farm accounts from 1996 to 2009.

Findings
– The paper finds that credit capacity roughly doubled for Danish farmers over the period, and that utilization of credit capacity generally was proportional to capacity change, utilization being higher for dairy and pig farms, than for crop farms.

Research limitations/implications
– Changes in credit reserves may have important implications for risk management practice, investment and technology adoption and related policy issues. The method is limited by the possibility of strategic behavior of lenders during credit cycle busts. In credit cycle booms, the method gives a good basis for the estimates of change in credit reserves.

Practical implications
– In a period of increasing credit reserves, risk management institutions are unlikely to develop. Like agricultural policy, access to credit may crowd out market-based risk management.

Originality/value
– The study represents a novel application and interpretation of a well-known method.
Quantifying the sources of revenue variation in the Northern Great Plains
Authors: C. Hadrich Joleen 
Published: November 2013

Purpose
– The purpose of this paper is to determine the sources and factors affecting farm revenue variation on crop and livestock farms in the Northern Great Plains.

Design/methodology/approach
– A two method approach is used. Variance decomposition analysis is completed on an 18-year balanced panel data set of North Dakota producers to determine the sources of farm revenue variation. The second component of this research uses a random effects estimator to determine the effect of farm characteristics on farm revenue variation measured by coefficient of variation.

Findings
– Crop revenue is the largest source of farm revenue variation, with crop insurance being the largest source of revenue variation diversification. Small market crops and corn were found to increase revenue variation compared to those operations that received the largest sum of their revenue from wheat. Government payments and insurance payments were also found to increase farm revenue variation indicating they may provide an incentive to plant more risky crops.

Originality/value
– This analysis examined specific enterprises that affect farm revenue variation, which has not been examined in earlier work. This distinction allows for focus on potential policy implications of small market crops and new crops in “transitional planting zones”.
Resettled refugee community perspectives to the Canterbury earthquakes
Authors: Marlowe Jay 
Published: November 2013

Purpose
– This research project examined resettled refugees’ perspectives on the Canterbury Earthquakes to better understand the organisational implications for disaster preparedness and response with culturally and linguistically diverse groups.

Design/methodology/approach
– The method of data collection for this exploratory pilot study involved conducting semi-structured focus group discussions during January 2012 with the Bhutanese, Afghani and Ethiopian communities. The project was conducted in partnership with Refugee Services Aotearoa which is New Zealand's primary refugee resettlement organisation.

Findings
– The participant comments identify the importance of local ethnic community responses to a natural disaster. The need for a pre-established meeting centre(s) and community liaisons with key support organisations was highlighted as vital. Central to recovery is how organisations can work alongside refugee communities in disaster preparedness and response opportunities.

Originality/value
– The paper offers insight into the additional considerations of disaster risk reduction strategies with refugee background communities – a group that is relatively under-researched in disaster contexts.
Lessons from disaster: the power and place of story
Authors: Mutch Carol , Marlowe Jay 
Published: November 2013

Purpose
– The purpose of this paper is to view the human experiences of the Canterbury earthquakes through a varied set of disciplinary lenses in order to give voice to those who experienced the trauma of the earthquakes, especially groups whose voices might not otherwise be heard.

Design/methodology/approach
– The research designs represented in this special issue and discussed in this introductory paper cover the spectrum from open-ended qualitative approaches to quantitative survey design. Data gathering methods included video and audio interviews, observations, document analysis and questionnaires. Data were analysed using thematic, linguistic and statistical tools.

Findings
– The themes discussed in this introductory paper highlight that the Canterbury response and recovery sequence follows similar phases established in other settings such as Hurricane Katrina and the Australian bushfires. The bonding role of community networks was shown to be important, as was the ability to adapt formal and informal leadership to manage crisis situations. Finally, the authors reinforce the important protocols to follow when researching in sensitive contexts.

Research limitations/implications
– The introductory paper only discusses the articles in this special issue but it is important to acknowledge that there are other groups whose stories were not shared due to logistical limitations.

Originality/value
– This introductory paper sets the scene for the articles that follow by outlining the importance of the human stories of the Canterbury earthquakes, through the eyes of particular groups, for example, medical staff, schools, women, children and refugees. The approach of viewing the experience through different community voices and disciplinary lenses is novel and significant. The lessons that are shared will inform future disaster preparedness, response and recovery policy and planning.
“Sailing through a river of emotions”: capturing children's earthquake stories
Authors: Mutch Carol 
Published: November 2013

Purpose– The three case studies reported in this paper are drawn from a wider project in which schools in Canterbury, New Zealand, were invited to tell the stories of their experiences of the 2010/2011 earthquakes. The purpose of this paper is to capture the stories for the schools, their communities and for New Zealand's historical record.Design/methodology/approach– The approach taken was qualitative and participatory. Each school had control over their project design and implementation. The researchers were partners and facilitators in assisting each school to reach its goal. In these three case studies approximately 100 participants including principals, teachers, students and families were engaged in generating data to create tangible and long-lasting end products.Findings– The two themes from the data highlighted in this paper are: first, the importance of providing emotional processing opportunities for children without severe post-trauma symptoms to support their recovery and second, the ways in which children can be engaged and given a voice in research that concerns them.Originality/value– The paper contributes to the wider collection of research on and about the Canterbury earthquakes by giving voice to children and highlighting the role of schools in post-disaster response and recovery. The “continuum of engagement” described here is a new and original model.
Preserving family and community: women's voices from the Christchurch earthquakes
Authors: Gordon Liz 
Published: November 2013

Purpose– The purpose of this paper is to highlight and report on women's work during and after the Christchurch earthquakes.Design/methodology/approach– The paper reports findings of some of a large number of life history interviews conducted with Christchurch women in 2012.Findings– Three specific sets of roles for women are identified, arising from the interviews that were undertaken. The first role is in keeping families together, meeting a range of diverse family needs and supporting all family members. The second role is in working with, and leading, post-quake services to offer disaster relief. Finally, a third role is in working in a range of ways to engage with and beautify communities and improve their lives.Practical implications– Women's work is often unseen in the post-earthquake environment. But this lack of visibility should not imply that women are not active in earthquake recovery.Originality/value– As far as the authors are aware, this is the first life history study of women undertaken to understand the impact of the earthquakes on their lives.
Pedagogy of love and care: shaken schools respond
Authors: O’Connor Peter 
Published: November 2013

Purpose
– The 22 February 2011 series of earthquakes that devastated large parts of the Canterbury region of New Zealand provides the dramatic backdrop to this paper, which explores the manner in which schools responded and recovered from the quakes. Drawing on interviews held 18 months later with principals, teachers and students, practical suggestions for how schools can manage risk, and prepare for future similar events are made. The manner in which schools altered, and in particular, the roles principals took, are examined. Finally, the central importance of care and love in schools in the quake-affected areas is considered.

Design/methodology/approach
– A qualitative research design using narrative enquiry approaches was used to capture the stories of principals, teachers, and students who had experienced both the earthquakes, and the recovery period following the trauma. Semi-structured interviews with participants were held over a period of days.

Findings
– The importance of being prepared for natural disasters is paramount for all New Zealanders in order to ensure health, safety, and cohesion on the day of an earthquake. However, the research reveals there is significance in having secure, meaningful, and honest relationships with school students to help raise the well-being of all affected by natural disasters.

Originality/value
– The paper continues to look at a pedagogy of love and care as a vital way to support, encourage, and aid children through their trauma and grief which continues long after the earthquake.
Recovering from the earthquake
Authors: Bateman Amanda , Danby Susan 
Published: November 2013

Purpose
– Traumatic events can cause post-traumatic stress disorder due to the severity of the often unexpected events. The purpose of this paper is to reveal how conversations around lived experiences of traumatic events, such as the Christchurch earthquake in February 2011, can work as a strategy for people to come to terms with their experiences collaboratively. By encouraging young children to recall and tell of their earthquake stories with their early childhood teachers they can begin to respond, renew, and recover (Brown, 2012), and prevent or minimise more stress being developed.

Design/methodology/approach
– The study involved collecting data of the participating children taking turns to wear a wireless microphone where their interactions with each other and with teachers were video recorded over one week in November 2011. A total of eight hours and 21 minutes of footage was collected; four minutes and 19 seconds of that footage are presented and analysed in this paper. The footage was watched repeatedly and transcribed using conversation analysis methods (Sacks, 1995).

Findings
– Through analysing the detailed turn-taking utterances between teachers and children, the orderliness of the co-production of remembering is revealed to demonstrate that each member orients to being in agreement about what actually happened. These episodes of story telling between the teachers and children demonstrate how the teachers encourage the children to tell about their experiences through actively engaging in conversations with them about the earthquake.

Originality/value
– The conversation analysis approach used in this research was found to be useful in investigating aspects of disasters that the participants themselves remember as important and real. This approach offers a unique insight into understanding how the earthquake event was experienced and reflected on by young children and their teachers, and so can inform future policy and provision in post-disaster situations.
The on-going psychological toll from the Canterbury earthquakes
Authors: (Libby) Gawith Elizabeth 
Published: November 2013

Purpose
– The purpose of this paper is to capture the stories of earthquake experiences from one community and relate this material to some of the psychological phases of recovery from a disaster.

Design/methodology/approach
– The approach taken was qualitative, explorative and participatory. The researchers were partners in the school project, as the school determined its own methodology, participation and end result. The audio or video interviews were open-ended and explored broad themes, in groups and individuals. Participants included multiple members of the same families. The stories of the participants were used to illustrate the psychological phases of recovery.

Findings
– The experiences of the research participants were reviewed through the psychological phases of recovery highlighted in the literature (e.g. Myers and Zunin, 2000). The phases identified in the stories indicate that the Christchurch situation is consistent with international experience. Additional psychological responses such as community bonding and resilience, as well as living with secondary stressors, were also identified.

Research limitations/implications
– There are some commonalities apparent for this group of interviewees, for example, many were together at the school, at the time of the 22 February 2011 earthquake. However, there are also many differences and unique experiences and as such, only tentative generalisations can be made from these interviews.

Originality/value
– The paper contributes to the wider collection of research on and about the Canterbury earthquakes by discussing elements of psychological recovery through the experiences of one community of parents, teachers and primary school children.
Difficulties of integrating older workers into the labor market: exploring the Israeli labor market
Authors: Axelrad Hila , Luski Israel , Miki Malul 
Published: November 2013

Purpose– The purpose of this article is to examine the existence of biased stereotypes about older workers. What are the economic implications of such biased stereotypes? Finally, what policy measures are required in order to achieve efficiency in the labor market?Design/methodology/approach– The authors grouped 25 opinions about older workers into three categories of stereotypes. The first category dealt with the productivity of older staff. The other two categories addressed their reliability and adaptability. The authors then questioned 312 Israeli respondents about the degree to which they agreed or disagreed with the opinions. Finally, the authors examined theoretically the economic effects of biased stereotypes about older workers.Findings– The study demonstrates that individual and organizational characteristics affect employers' attitudes. Age was a significant factor in all three categories. The older the respondent, the fewer prejudices he or she had against older workers. Other characteristics such as gender, interaction with older workers, the nature of the respondent's work in the organization, the age of the employees, and the size of the organization were all significant, but not always, and not in all three categories. The findings imply that there are biased stereotypes about older workers, so the allocation of workers is distorted, which leads to a failure of the market.Originality/value– The results strengthen the economic justification for policy intervention to correct the distorted level of employment of older workers in the labor market.