bluuebunny/crossref_metadata_2025_split huggingface dataset:
Corneal wavefront changes after photorefractive keratectomy surgery with aberration-free TM profile using the Schwind amaris 1050 device: 1 year follow up
Authors: khakpour Yaser , Soltani-Moghadam Reza , hajmohammadi Omid , Alizadeh Yousef , Azaripour Ebrahim 
Published: July 2024

Abstract

Background
One of the complications of photorefractive keratectomy surgeries is the induction of corneal aberrations. Nowadays, there are multiple devices with various ablation profiles to reduce this complication. This study aimed to investigate the level of corneal aberrations induced following the use of the Schwind Amaris 1050 device with Aberration-Free TM profile.
Methods
This prospective case series study involved preoperative evaluation using a Sirius device for 108 eyes (54 patients). Subsequently, they underwent PRK surgery with the Schwind Amaris 1050 excimer laser using the Aberration-Free TM profile. Follow-up examinations were conducted, and corneal aberrations were measured using aberrometry at 12 months post-surgery. Data regarding age, gender, refractive error, and pre- and post-operative spherical, coma, and trefoil aberrations were recorded. Data were analyzed using SPSS version 21.
Results
The mean preoperative RMS for coma (0.27 ± 0.12 µm), spherical (0.24 ± 0.1 µm), total HOA (0.42 ± 0.1 µm), and trefoil (0.19 ± 0.1 µm) was recorded. The mean RMS at 12 months post-surgery for total HOA (0.59 ± 0.21 µm), spherical (0.37 ± 0.23 µm), coma (0.32 ± 0.13 µm), and trefoil (0.21 ± 0.1 µm) showed statistically significant increases in the spherical, total HOA, and coma groups (P < 0.001), but not in the trefoil group (P = 0.135).
Conclusions
Ablation with the Schwind Amaris 1050 device using the Aberration-Free TM profile following PRK surgery induces corneal aberrations over 12 months. This finding contradicts the manufacturer's claims but requires further investigation over a longer period for confirmation.
The Efficacy of Conversional One Anastomoses Gastric Bypass post Sleeve Gastrectomy and Gastric Band: A Large Single Cohort Series
Authors: Lerch Aaron , Katneni Mokshitha , Martin Ian 
Published: July 2024

Abstract

Introduction
Conversional bariatric procedures are increasing, particularly conversional one-anastomosis gastric bypasses (cOAGB). This study reports long-term and patient-reported outcomes for cOAGB after laparoscopic adjustable gastric banding (LAGB) and sleeve gastrectomy (SG).
Methods
This retrospective single-cohort review of a prospective database examined all cOAGB cases (2016-2023). Perioperative morbidity, long-term surgical or endoscopic interventions, and patient-reported outcomes were analysed.
Results
Within the largest published cohort of 261 consecutive cOAGB patients, 60.9% had prior-LAGB and 39.1% had prior-SG. Within 30 days, three severe and 13 low-grade complications occurred without mortality, with 98.9% of patients home the following day. Twenty-four longer-term surgical interventions were performed for reflux, port-site hernia, perforated ulcer or adhesions. 14 cases of anastomotic ulcer and one reflux oesophagitis were managed conservatively.
60.9% of patients responded to the survey (35.7 months post-cOAGB). 37.1% reported heartburn and 23.9% reported regurgitation. 81.8% of patients reported they were happy with the procedure, and 78% reported they would choose it again, both outcomes associated with greater percentage excess weight loss (%EWL) and lower heartburn scores. Higher satisfaction was associated with less regurgitation or prior-LAGB.
Mean BMI (41.8 months after conversion) was 31.5kg/m2 (9.7kg/m2 less than before conversion), with mean %EWL of 64.6% (significantly higher in female patients) and mean TBWL of 22.5%.
Conclusion
cOAGB was found to be safe and effective for further weight loss or persistent reflux. Although these issues may not be fully resolved, the relative improvement is reflected in the strong satisfaction scores, supporting the use of this technique in conversional surgery.
A Study on the Correlation between Preoperative and Postoperative Sleep Disorders and Postoperative Complications in Elderly Patients Undergoing Radical Gastrectomy for Gastric Cancer
Authors: wang gang , pan shengjie 
Published: July 2024

Abstract

Objective
To investigate the association between preoperative and postoperative sleep disorders and postoperative complications in elderly patients undergoing radical gastrectomy for gastric cancer.
Methods: A retrospective analysis was conducted on the clinical data of 485 elderly patients who underwent gastric cancer surgery in our hospital from May 2020 to May 2023. Patients were categorized into groups based on the occurrence of postoperative complications within 30 days after surgery: no complications, mild complications, and severe complications. Clinical data of patients in different groups were compared and analyzed.
Results: A total of 485 gastric cancer patients were included in this study, among whom 325 patients had no postoperative complications, accounting for 67.01%; 139 patients had mild complications, accounting for 28.66%; and 21 patients had severe complications, accounting for 4.33%. Comparison of Pittsburgh Sleep Quality Index (PSQI) scores (preoperative and postoperative) among the three groups showed statistically significant differences (P < 0.05). Compared with the group with no complications, patients in the severe complications group and mild complications group had significantly higher PSQI scores (P < 0.05). Ordered logistic regression analysis revealed that preoperative and postoperative PSQI scores were factors influencing the occurrence of postoperative complications in elderly patients undergoing radical gastrectomy for gastric cancer (P < 0.05). A higher preoperative PSQI score was associated with an increased risk of postoperative complications, and similarly, a higher postoperative PSQI score was associated with an increased risk of postoperative complications. Spearman correlation analysis results showed a positive correlation between preoperative PSQI score and postoperative complication severity, as well as between postoperative PSQI score and postoperative complication severity in elderly gastric cancer patients.
Conclusion: Preoperative and postoperative sleep disorders are closely associated with postoperative complications in elderly patients undergoing radical gastrectomy for gastric cancer. Higher preoperative and postoperative PSQI scores indicate an increased risk of postoperative complications.
Covid‐19 Vaccine Acceptance in Pregnant Women Attending the Outpatient Clinic at Police Hospital, Khartoum, Sudan 2023
Authors: Awad Mustafa Sabir Abakar 
Published: July 2024

Abstract

Background:
Shortly after the COVID-19 Pandemic multiple researches were focused on manufacturing and synthesizing a vaccine to overcome the disease. Pregnant women being at increased risk of critical illness and having high rates of ICU admission especially due to respiratory prone illnesses, and Sudan being a third world country have high illiteracy rates among females, hence it was essential to determine vaccine acceptance and hesitancy attitudes toward COVID-19 vaccines in pregnant women.
Methodology:
A prospective cross sectional hospital based study, it was conducted at Police Hospital which is a tertiary specialized university hospital that falls under the administration of National Ribat University Faculty of Medicine. The sample size consisted of 240 pregnant women who attended the outpatient clinic during the study period. The collected data was analyzed using Statistical package for social sciences (SPSS) V26.
Results:
Out of all the 240 participants, 89 individuals (37%) expressed their willingness to receive the vaccination if it were advised for pregnant women. The primary reasons for denial were insufficient data about the safety of COVID-19 vaccines in pregnant individuals and concerns about potential harm to the developing fetus. There was a modest positive association observed between the acceptance of the COVID-19 vaccine and the number of children of school age. Pregnant women in the first trimester shown greater willingness to receive the COVID-19 vaccine compared to those in the second and third trimesters.
Conclusion:
The current study demonstrated a poor level of acceptance of COVID-19 vaccination among a group of pregnant women. The primary cause of reluctance was apprehension regarding the safety of the vaccine. An important step in developing effective immunization tactics during the ongoing epidemic is to identify the attitudes prevalent among priority groups.
Challenges of Implementing Outsourcing of Primary Health Services from The Perspective of Stakeholders
Authors: Ebrahimipour Hosein , yousefi mehdi , tabatabaee Saeed , hoshmand Elahe , taghipour Ali , jamili sara 
Published: July 2024

Abstract

Background
The primary function of health systems is to provide high-quality and universal health services. Outsourcing, synonymous with contracting-out, has been common in many market-oriented health care reforms. But Lack of attention to the obstacles and challenges of outsourcing health services such as economic issues, responsibility and accountability, human resources challenges, structural problems and private companies, efficiency and planning challenges may lead to failure and irreparable damage to the health system. The present study aimed at identifying the challenges of Outsourcing Health Services to the Private Sector.
Method
This is a qualitative study that was conducted with the approach of Directed content analysis in 2023. The sampling method was purposeful and sampling continued until data saturation. Data analysis was done using Colaizzi’s method and MAXQAD software.
Results
After extracting the data, 3 main classes including Challenges of the contractor, Challenges of the employer (university), Manpower challenges and 14 subclasses were extracted.
Conclusion
The outcomes of this study revealed that outsourcing is one of the basic needs to advance organizational goals. Nonetheless, its current implementation method is not very appropriate. Challenges identified as obstacles to the proper implementation of the partnership plan with the private sector in the field of health are sometimes an integral part of such plans. These challenges must be resolved before the implementation of the plan and during planning by conducting studies and reviewing the project background. This will help to prevent further problems during the execution.
An Empirical Study on Factors of Influence for Single-Frame Supervised Temporal Action Detection
Authors: Jo Hyejeong , Gwon Huiwon , Jo Sunhee , Jung Chanho 
Published: July 2024

Abstract

Owing to the substantial time and labor demands associated with video annotation for fully-supervised temporal action detection (TAD), extensive research has been devoted to the domain of weakly-supervised TAD. However, existing weakly-supervised TAD approaches still suffer from severe localization errors due to the absence of fine-grained frame-level annotations. To tackle this issue, single-frame supervised TAD has been recently proposed as a potential method. This paper does not introduce a new approach. Instead, the aim of this paper is to conduct an empirical study on factors of influence for single-frame supervised TAD, which have not yet been studied and thus are still unclear. We go back to basics and investigate the effects of several fundamental components on the performance of single-frame supervised TAD: 1) feature extraction, 2) feature modeling, 3) temporal embedding, 4) classification head, and 5) video-level classification loss. In this investigation, we explore the potentials of traditional technical solutions in the task of single-frame supervised TAD and unveil the benefits of such solutions, which have not yet been reported to the research community. Based on the findings, we build a baseline detector, which achieves the state-of-the-art performance. It should be noted that, to make up for the limit of mAP (mean average precision), not only mAP but also VCCR (video-level classification correctness rate) is employed in the performance evaluation. Make a note of the fact that the VCCR is a supplementary metric supporting the mAP. We hope that our work can facilitate future research in this field.
A Novel Approach to produce Soy Protein Isolate: Direct Enzymatic Hydrolysis of High-Temperature Soybean Meal Using Proteinase Produced by Microbial Solid-State Fermentation
Authors: Zhu Junsong , Liu Dandan , Lu Feng , Liu Xiaoshuang , Wang Yucheng , Ma Haile 
Published: July 2024

Abstract

This study proposed a novel extraction method for soy protein isolate (SPI), which involved solid-state fermentation of high-temperature soybean meal. The proteinases secreted by microorganisms acted on the high-temperature soybean meal, making the SPI easier to extract. The study concludes that Bacillus amyloliquefaciens subsp. plantarum CICC 10265 could be used for solid-state fermentation of soybean meal, and the fermentation effect was good, with a yield of 41.91% for SPI. Compared to the direct extraction of SPI from high-temperature soybean meal, the yield had increased by 130.19%. Meanwhile, we also conducted research on the losses during the SPI extraction process. Through experiments, the study identified the patterns of protease activity changes and microbial colony growth during solid-state fermentation of soybean meal by Bacillus amyloliquefaciens subsp. plantarum CICC 10265. It was concluded that extracting SPI after 8 hours of fermentation is more suitable. The experimental results indicated that the total amino acid content of SPI extracted from fermented soybean meal was 2.1% higher compared to SPI extracted from low-temperature soybean meal.
Calibration and Release of Magnetograms/Dopplergrams Obtained at the Mt. Wilson 150-foot Tower Telescope (MWO)
Authors: Ulrich Roger , Boyden John , Tran Tham 
Published: July 2024

Abstract

The Mt. Wilson Observatory archive of observations of solar disk magnetic fields, Doppler velocities and spectral line intensities is a resource for the study of the sun’s state over a period from 1967 to 2013. Instrument changes/upgrades during this time have to be taken into account in the interpretationof this record. Portions of this record have been previously released. This publication documents the data record in order to allow its independent interpretation. The archive is available through two directory trees which can be accessed at http://sha.stanford.edu/mwo/msm.html. Calibration of the observations is impacted by the solar surface convective flows which produce offsets to both the differential rotation and meridional circulation functions. The effectsof these offsets have been reduced in this and other publications by temporal averaging.
Lactate aggravates myocardial Ischemia-Reperfusion injury through SLC39A14-mediated ferroptosis
Authors: Hua Xu , Huang Xian-Xi , He Ling-Bin , Zhang Xin 
Published: July 2024

Abstract

Ferroptosis, a new form of iron-dependent regulated cell death, is driven by lipid peroxidation, playing a role in various pathogenic processes. Although the role of ferroptosis in myocardial ischemia-reperfusion injury (MIRI) has been intensively studied, the underlying molecular mechanisms remained largely unclear. Here, we showed that lactate participated in ferroptosis induced by hypoxia/reoxygenation in H9C2 cell. Importantly, hypoxia/reoxygenation induced apoptosis through aggravating ferroptosis by targeting NRF2/system Xc-/GPX4 axis, which reduced ROS scavenging. In addition, lactate promoted SLC39A14 expression followed by elevation of Fe2+ uptake, which generated superfluous ROS via the Fenton reaction. The excessive ROS could finally induce lipid peroxidation, thereby leading to ferroptosis characterized by cell apoptosis. Together, our findings suggest that lactate plays a crucial role as a novel regulator of ferroptosis, and reducing lactate levels might potentially offer a promising therapeutic strategy for managing myocardial ischemia-reperfusion injury.
Comparison the effect of atorvastatin and forskolin on memory after global cerebral ischemia in male rats
Authors: Bashghareh Alieh , Modarresi Peyman , Mahdavian Samaneh , Hedayatpour Azim 
Published: July 2024

Abstract

Objective: This study aimed to improve memory impairment after global cerebral ischemia. For this purpose, we used atorvastatin and forskolin after ischemia to improve neuronal injury and memory problems then compared the effect of these treatments to find the more effective strategy.
Methods: Adult male rats (n=70) were divided into 7groups (n=10). Group 1: control; group 2: sham; group 3: CI (global cerebral ischemia only); group 4: CI+ forskolin; group 5: CI+ atorvastatin; group 6: CI+vehicle1; group 7: CI+vehicle2. Ischemia was induced by occluding the bilateral common carotid artery. Atorvastatin and forskolin were injected intraperitoneally 4, 24, and 42 h after ischemia in group 5 and group6. Memory was evaluated with a water maze test. Data were analyzed by one-way ANOVA.
Results: The level of significance was 5% (p ≤ 0.05). Atorvastatin and forskolin treatment significantly reduced neuronal injury and improved memory in comparison with the ischemia group. Rats in the forskolin treated group had better performance in the Morris water maze test.
Conclusion: Our findings showed that forskolin is more effective compared to atorvastatin after global cerebral ischemia.
Beyond Borders: Exploring the Lived Experiences of International Migrant Women in Nigeria, a Deep Dive into Healthcare Realities and Utilization
Authors: Nwafor Juliet , Edet Rowland , Nwokoch Ezebunwa 
Published: July 2024

Abstract

This study explored access to and utilization of healthcare facilities among migrant women in an urban slum community in Nigeria, focusing on factors influencing healthcare-seeking behaviors and the implications for public health interventions. A qualitative case study-oriented research design was employed, involving in-depth interviews with 21 migrant women of reproductive age and 4 key informant interviews with healthcare workers in the Ayobo community of Lagos State, Nigeria. Data collection occurred from June to September 2018, and thematic analysis was used to interpret the findings. Three main themes emerged: living conditions, pattern of healthcare utilization, and factors influencing accessibility and utilization of healthcare facilities. Living conditions were characterized by housing instability, limited access to clean water and sanitation, and financial constraints. Migrant women demonstrated a preference for traditional remedies over formal healthcare due to cultural beliefs and perceived effectiveness. Recommendations from peers and family members influenced healthcare decisions. Targeted public health interventions are needed to address the multifaceted challenges faced by migrant women, including improving housing conditions, providing access to clean water and sanitation, and promoting culturally sensitive healthcare programs.
Intravenous hydrogen nanobubbles effect on cardiac physiology and quality of life: a single blind, dose-response study
Authors: Hernowo Aditya Tri , Subagjo  , Indrajani Olly , Sudarwanto Gatot , Sarwawati  , Aristyani Sherry , Sumitro Sutiman Bambang 
Published: July 2024

Abstract

Hydrogen nanobubbles (HNBs) showed promise for cardiovascular health and health-related quality of life (HRQoL). This study assessed intravenous HNB effects on cardiovascular parameters and HRQoL through a randomized, single-blind trial with 52 participants across six groups (control and five HNB dosages). Over 10 sessions in 5 weeks, the outcomes were measured included blood pressure, heart rate, left ventricular ejection fraction, and HRQoL via SF-36 survey. HNB administration significantly reduced systolic (144.94 to 129.88 mmHg) and diastolic (87.18 to 78.89 mmHg). Heart rate decreased slightly, and left ventricular ejection fraction increased marginally. Improvements in diastolic function, flow-mediated dilation, and HRQoL (general health, mental health, social functioning, bodily pain) were noted. Dose-dependent effects were significant at higher doses. In conclusion, HNB therapy could enhance cardiovascular function and HRQoL. Optimizing dosages and integrating comprehensive health interventions could enhance therapeutic outcomes, providing a holistic approach to managing cardiovascular health.
Measuring multidimensional poverty and child poverty in Central Sudan: Evidence from AlJezira State
Authors: Ali Gowaria Dafa Alla Abd-Elgdir 
Published: July 2024

Abstract

This paper presents an in-depth analysis of multidimensional poverty in central Sudan utilizing two methodologies: (MPI) and multiple overlapping deprivation analysis (MODA). The research is based on primary data collected through structured questionnaires by the Central Bureau of Statistics in 2023, covering 43 administrative units in AlJezira State and interviewing 764 randomly selected households. The study revealed that approximately one-fifth of the population in the study area experiences multidimensional poverty, with significant deprivations in education, health, and standard of living. Additionally, child poverty is notably high, with a multidimensional headcount ratio of 26% among children under five, which decreases by 5 percentage points when applying a reweighted MODA approach developed by the researchers. The practical significance of this study lies in its potential to inform targeted poverty alleviation policies and interventions, particularly in rural areas and among young children. Theoretically, this research contributes to the literature by demonstrating the value of combining MPI and MODA methodologies to capture a more comprehensive picture of poverty. The innovative aspect of this manuscript is the application of a reweighted MODA approach, which provides a nuanced understanding of child poverty and offers new insights for policy formulation. The findings underscore the urgent need for tailored strategies to address the multifaceted nature of poverty in central Sudan.