bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ecclesiastical Policies on Education: A Democratic Game of Winners and Losers?
Authors: Aldrin Viktor 
Published: July 2024

Abstract
In the post-secular societies of Scandinavia and Great Britain, Christian denominations have had to reconstruct their identities as educational agents. This article focuses on the Church of England and the Church of Sweden, and their changed self-identification as expressed in their educational policy documents. Whereas the Church of England’s discourses are of partnership and business competition, the Church of Sweden’s discourses are about the Apocalypse and external threats. These approaches are analysed using Habermas’s concept of religion, identifying a transformation of religious language into secular argumentation to become viable in the secular public space. The question posed is: “Is theology exerting less influence over education in Scandinavia and Great Britain?”
Epigenetic differences in the tumor suppressor genes MLH1 and p16INK4a between Nepalese and Swedish patients with colorectal cancer
Authors: Ghimire Bikal , Kurlberg Göran , Falk Peter , Singh Yogendra , Wettergren Yvonne 
Published: July 2024

Abstract

Objectives
Colorectal cancer (CRC) is one of the most prevalent cancer types worldwide, exhibiting significant variance in incidence rates across different ethnicities and geographical regions. Notably, there is a rising incidence of CRC among younger adults, particularly evident in advanced stages, with a more pronounced trend observed in developing nations. Epigenetic alterations potentially play a role in the early onset of CRC and could elucidate interpopulation disparities. This study aimed to examine DNA methylation levels in the tumor suppressor genes MLH1 and p16INK4a, comparing Nepalese and Swedish patients with CRC.

Methods
Patients who underwent CRC surgery at Tribhuvan University Teaching Hospital, Nepal (n=39), and Sahlgrenska University Hospital, Sweden (n=39) were included. Demographic and clinicopathological data were analyzed, and pyrosequencing was employed to determine methylation levels in the MLH1 promoter region and the first exon of p16INK4a in tumor tissues and adjacent mucosa located 10 cm from the tumor site. Subsequently, methylation status was compared between Nepalese and Swedish patients and correlated with clinicopathological parameters.

Results
Nepalese and Swedish patients displayed equal levels of MLH1 and p16INK4a methylation in tumors, but Nepalese patients exhibited a significantly higher level of MLH1 methylation in mucosa compared to Swedish patients (p=0.0008). Moreover, a greater proportion of Nepalese patients showed MLH1 methylation in mucosa compared to Swedish patients (31 vs. 2.6 %). Aberrant methylation of p16INK4a was also observed in the mucosa of Nepalese patients, characterized by high methylation at specific sites rather than uniform methylation across CpG sites. There were no significant differences in methylation levels based on tumor location among Nepalese patients, whereas Swedish patients exhibited higher methylation in right- compared to left-sided colon tumors. Swedish patients showed an increase in p16INK4a methylation in tumors with advancing age.

Conclusions
Nepalese and Swedish patients displayed equal levels of MLH1 and p16INK4a methylation in tumors. In contrast, Nepalese patients had a higher level of MLH1 methylation as well as aberrant methylation of p16INK4a in mucosa compared to Swedish patients. These epigenetic differences may be linked to environmental and lifestyle factors. Ongoing research will further explore whether hypermethylation in the mucosa of Nepalese patients is associated with tumorigenesis and its potential utility in screening high-risk patients or predicting recurrence.
Learning curves for high tibial osteotomy using patient-specific instrumentation: a case control study
Authors: Stimolo Davide , Leggieri Filippo , Matassi Fabrizio , Barra Angelo , Civinini Roberto , Innocenti Matteo 
Published: July 2024

Abstract

Objectives
Three-dimensional (3D) planning and Patient Specific Instrumentation (PSI) can help the surgeon to obtain more predictable results in Medial Opening Wedge High Tibial Osteotomy (mOW-HTO) than the conventional techniques. We compared the accuracy of the PSI and standard techniques and measured the learning curve for surgery time and number of fluoroscopic shots.

Methods
We included the first 12 consecutive cases of mOW-HTO performed with 3D planning and PSI cutting guides and the first 12 non-supervised mOW-HTO performed with the standard technique. We recorded surgery time and fluoroscopic time. We calculated the variation (Δ delta) between the planned target and the postoperative result for Hip Knee Ankle Angle (HKA), mechanical medial Proximal Tibia Angle (MPTA), Joint Line Convergence Angle (JLCA) and tibial slope (TS) and compared it both groups. We also recorded the complication rate. We then calculated the learning curves for surgery time, number of fluoroscopic shots, Δ from target in both groups. CUSUM analysis charts for learning curves were applied between the two groups.

Results
Mean surgical time and mean number of fluoroscopic shots were lower in PSI group (48.58±7.87 vs. 58.75±6.86 min; p=0.034 and 10.75±3.93 vs. 18.16±4.93 shots; p<0.001). The postoperative ΔHKA was 0.42±0.51° in PSI vs. 1.25±0.87° in conventional, p=0.005. ΔMPTA was 0.50±0.67° in PSI vs. 3.75±1.48° in conventional, p<0.001; ΔTS was 1.00±0.82° in PSI vs. 3.50±1.57° in conventional, p<0.001. ΔJLCA was 1.83±1.11° in PSI vs. 4±1.41° in conventional, p<0.001. The CUSUM analysis favoured PSI group regarding surgery time (p=0.034) and number of shots (p<0.001) with no learning curve effect for ΔHKA, ΔMPTA, ΔJLCA and ΔTS.

Conclusions
PSI cutting guides and 3D planning for HTO are effective in reducing the learning curves for operation time and number of fluoroscopic shots. Accuracy of the procedure has been elevated since the first cases.
Modal analysis for the non-destructive testing of brazed components
Authors: Bobzin Kirsten , Heinemann Hendrik , Hebing Julian , Erck Marvin , Menke Janis 
Published: July 2024

Abstract
In brazing processes, the formation of defects within the brazing joint due to deviations in brazing process and material is a recurring problem. These affect the component quality as well as the component properties. In this study, modal analysis is fundamentally investigated as a potential tool for non-destructive testing of brazing joints as well as for fast quantification of the precision of the brazing process. The aim of the investigation is to detect defects in brazed components. For this purpose, test specimens in defect-free and defect-containing form are brazed by means of a high-vacuum furnace. The subsequent recording and real-time analysis of the oscillation behavior of these test specimens is to be used to evaluate the quality of these brazed joints. A method, developed specifically for this purpose, automatically evaluates the recorded oscillation profile based on several defined frequency positions. For the first time, the results show that a reproducible classification of brazing seam quality into OK and not-OK can be made by comparing several frequency positions with already known oscillation profiles.
Nietzsche’s Sorrentino Politics
Authors: Murray Peter Durno 
Published: July 2024

Abstract
The passages composed by Nietzsche around the time he spent at Sorrento reflect an engagement with the anarcho-utopian socialist milieu into which he had been introduced by Malwida von Meysenbug. The “Sorrentino politics” that appear in Human, All Too Human I and II and later works need to be understood in the context of an affirmative form of political thought that could remedy the pessimism and nihilism that he finds in the politics of all sides. Nietzsche argues that the monarchical state, modern industrialism, and the restricted ownership of capital and property all undermine the goal of creating a life-affirming culture for Europe. He also provides a criticism of a utopian teleology of equality in the future – whether religious or socialist – that imposes an objective notion of purpose. Nietzsche rejects the Schopenhauerian pessimism of resignation while affirmatively engaging with the thought of Alexander Herzen and Guiseppe Mazzini.
Mündigkeit als Hybris? Über implizite Anthropologie und das Ideal des „mündigen Athleten“
Authors: Kluck Steffen 
Published: July 2024

Zusammenfassung
Der Beitrag unternimmt es, das Konzept der Mündigkeit historisch herzuleiten und zu zeigen, wie es im Ideal des „mündigen Athleten“ weiterwirkt. Ausgehend von begriffsgeschichtlichen Spuren wird durch eine konkrete Fallanalyse gezeigt, dass das Ideal für Sportler und Sportlerinnen problematische Konsequenzen zeitigt. Um diesen zu begegnen, wird ein erweitertes Verständnis von Mündigkeit entwickelt, welches im Wesentlichen eine Mündigkeit gegen sich selbst fordert. Es kommt der Mensch als Person in den Fokus, die sich mit heteronomen Einflüssen wie Gefühlen auseinanderzusetzen hat. Die Verteidigung des Konzepts erfolgt durch Aufzeigen theoretischer Reperspektivierungen, wobei zugleich auf neue theoretische Probleme hingewiesen wird. Insgesamt zeigt sich so die Relevanz anthropologischer Reflexionen für sportspezifische Fragestellungen.
Literature Review: Dampak Stunting terhadap Pertumbuhan dan Perkembangan Anak
Authors: Laily Linuria Asra , Indarjo Sofwan 
Published: July 2024

Abstrak
Indonesia tergolong dalam negara dengan prevalensi stunting tinggi. Berdasarkan hasil Survei Status Gizi Indonesia (SSGI) tahun 2021 angka prevalensi stunting di Indonesia sebesar 24,4%, angka ini menurun 6,4% dari angka 30,8% pada 2018. Meskipun demikian, masalah kesehatan ini memiliki dampak serius pada perkembangan dan pertumbuhan anak yakni dapat menyebabkan tidak optimalnya proses tumbuh kembang yang irreversible. Penelitian bertujuan menghimpun informasi untuk mengetahui hubungan kejadian stunting pada tumbuh kembang anak. Penelitian ini merupakan Systematic Literature Review dengan Meta-analisis. Dilakukan dengan mengambil artikel dari jurnal nasional maupun internasional melalui database electronic Pubmed dan Google Scholar dalam rentang waktu 2012-2022 kemudian dianalisis dengan software Openmee. Hasil analisis dilakukan pada 8 artikel jurnal terpilih menunjukkan bahwa stunting memiliki hubungan dengan variabel tumbuh kembang anak yakni motorik halus, motorik kasar, bahasa dan komunikasi, serta sosial emosional masing-masing memiliki p-value (p<0,001; p<0,001; p<0,001; p=0,002). Dapat disimpulkan terdapat korelasi yang signifikan antara stunting dengan proses tumbuh kembang anak. Hal ini dapat menyebabkan menurunnya kualitas sumber daya manusia, sehingga dibutuhkan perhatian dalam penanggulangan stunting.
Kata Kunci: Stunting, Status Gizi, Pertumbuhan, Perkembangan

Abstract
Indonesia is classified as a country with a high prevalence of stunting. Based on the results of the 2021 Indonesian Nutritional Status Survey (SSGI), the stunting prevalence rate in Indonesia was 24.4%; this figure decreased by 6.4% from 30.8% in 2018. Nonetheless, this health problem has a serious impact on the development and growth of children, which can lead to non-optimal growth processes that are irreversible. The research aims to collect information to determine the relationship between stunting and child development. This study is a meta-analysis of a systematic literature review. This was done by taking articles from national and international journals through the Pubmed and Google Scholar electronic databases in the 2012–2022 period and then analyzing them with the Openmee software. The findings of an analysis of 8 selected journal articles show that stunting has a relationship with child growth and development variables such as fine motor, gross motor, language and communication, and social-emotional, each of which has a p-value (p 0.001, p 0.001, p = 0.002). It can be concluded that there is a significant correlation between stunting and child development. This can lead to a decrease in the quality of human resources, so attention is needed when tackling stunting.
Keyword: Stunting, Nutritional Status, Growth, Development
Faktor yang Mempengaruhi Perilaku Ibu dalam Pemeriksaan IVA (Inspeksi Visual Asam Asetat)
Authors: Indriana Risma , Siyam Nur 
Published: July 2024

Abstrak
Penyakit kanker merupakan salah satu penyebab kematian utama di seluruh dunia. Kanker serviks adalah suatu keganasan yang disebabkan oleh virus HPV (Human Papilloma Virus). Berdasarkan Data Globocan (IARC) 2020, kanker serviks merupakan jenis kanker dengan insiden terbanyak keempat di dunia dari seluruh jenis kanker pada wanita yaitu sekitar 6,5%. Kejadian kanker serviks dapat dicegah dengan deteksi dini lesi prakanker. Salah satu deteksi dini lesi prakanker antara lain melalui Tes Inspeksi Visual Asam Asetat. Penelitian ini bertujuan untuk mengetahui faktor yang berhubungan dengan perilaku ibu dalam pemeriksaan tes IVA di wilayah kerja Puskesmas Sragen. Jenis penelitian ini adalah analitik observasional dengan rancangan studi cross sectional. Sampel terdiri dari 53 responden yang diambil dengan teknik purposive sampling. Pengambilan data pada peneltian ini menggunakan kuesioner. Analisis data menggunakan Fisher Exact test. Hasil penelitian menunjukkan bahwa nilai p value variabel usia (p=0,154), tingkat pendidikan (p=0,177), status pekerjaan (p=0,277), tingkat pengetahuan (p=0,005), dukungan keluarga (p=1,00), persepsi dukungan petugas kesehatan (p=0,026), keterpaparan informasi (p=0,031), dan sikap (p=1,00). Simpulan dalam penelitian ini adalah terdapat hubungan antara tingkat pengetahuan, persepsi dukungan petugas kesehatan, dan keterpaparan informasi.

Abstract
Cancer is one of the leading causes of death worldwide. Cervical cancer is a malignancy caused by the HPV (Human Papilloma Virus). Based on Globocan Data (IARC) 2020, cervical cancer is a type of cancer with the fourth most incidence in the world of all types of cancer in women, which is around 6.5%. The incidence of cervical cancer can be prevented by early detection of precancerous lesions. One of the early detection of precancerous lesions is through the Visual Inspection with Acetic Acid Test. This study aims to determine the factors related to the behavior of the mother in the VIA test in the working area of ​​the Sragen Public Health Center. This type of research is analytical observational with a cross sectional study design. The sample consisted of 53 respondents who were taken by purposive sampling technique. Collecting data in this research using a questionnaire. The data analysis used Fisher Exact test. The results showed that the p value of the variable age (p=0.154), education level (p=0.177), employment status (p=0.277), knowledge level (p=0.005), family support (p=1.00), perceptions of health workers support (p=0.026), information exposure (p=0.031), and attitudes (p=1.00). The conclusion in this study is that there is a relationship between the level of knowledge, perceptions of health workers support, and exposure to information.
Kejadian Kematian COVID-19 dan Determinannya di Kabupaten Sragen
Authors: Pungkasari Roro Trias , Siyam Nur 
Published: July 2024

Abstrak
Case Fatality Rate (CFR) COVID-19 Sragen masih tergolong tinggi yaitu 7,8%, diatas CFR Jawa Tengah (5,2%) dan CFR nasional (2,5%). Tujuan penelitian ini adalah memberikan gambaran terkait kejadian kematian COVID-19 dan determinannya di Kabupaten Sragen tahun 2022. Penelitian ini dilaksanakan dari bulan Juli sampai September 2022. Jenis penelitian ini adalah deskriptif kuantitatif, cross-sectional dan studi ekologi. Sampel untuk kasus kematian sebanyak 129 dan untuk kasus sembuh COVID-19 sebanyak 2.713, diambil dengan teknik total sampling. Data dianalisis menggunakan analisis univariat dan bivariat. Hasil penelitian ini menunjukkan bahwa kasus kematian COVID-19 lebih lebih banyak terjadi pada laki-laki (65,9%), orang dengan umur >65 tahun (39,5%), orang yang bertempat tinggal di perkotaan (73,6%), orang dengan penyakit komorbid (96,9%), orang yang belum melakukan vaksinasi COVID-19 (55,8%), serta terdapat hubungan antara umur (p=0,000) dan kepadatan penduduk (p=0,000) dengan kematian COVID-19. Simpulan penelitian ini adalah karakteristik tertentu dominan dalam kematian COVID-19 dan terdapat hubungan antara umur dan kepadatan penduduk dengan kematian COVID-19.

Abstrak
Sragen's COVID-19 Case Fatality Rate (CFR) is still relatively high at 7.8%, above CFR of Central Java (5,2%) and national (2.5%). The purpose of this study was to provide overview of the incidence of COVID-19 death and its determinants in Sragen Regency in 2022. This research was conducted from July to September 2022. This type of research is descriptive quantitative, cross-sectional, and ecological study. Sample for death cases are 129 and recovered cases are 2,713, taken by total sampling. Data were analyzed using univariate and bivariate analysis. The results of this study indicate that COVID-19 death cases are more common in men (65.9%), people aged >65 years (39.5%), people who live in urban areas (73.6%), people with comorbid diseases (96.9%), people who have not had COVID-19 vaccinations (55.8%), and there is a relationship between age (p=0.000) and population density (p=0.000) with COVID-19 deaths. Conclusion of this study is that certain characteristics are dominant in COVID-19 deaths and there is a relationship between age and population density and COVID-19 deaths.
Savižudiškų minčių intensyvumo skalė (SIDAS) ir Savižudiško elgesio klausimynas – patikslintas (SBQ-R): lietuviškų versijų psichometriniai rodikliai
Authors: Gužas Jokūbas , Skruibis Paulius , Mažulytė-Rašytinė Eglė , Grigienė Dovilė , Dadašev Said , Rimkevičienė Jurgita , Gailienė Danutė 
Published: July 2024

The Suicidal Ideation Attributes Scale (SIDAS) and the Suicidal Behaviors Questionnaire-Revised (SBQ-R) are widely used psychological instruments for assessing people‘s suicidal ideation and suicidal behavior. The aim of this study was to examine the psychometric characteristics of the Lithuanian versions of the SIDAS and SBQ-R. We analysed data collected from four samples: a Lithuanian general population quota sample based on age, gender and place of residence (N = 697, 52.9% women, aged 18–79 years); a sample of students (N = 2013, 72 % women, aged 18–29 years); a clinical sample of suicidal patients (N = 35, 77.1% women, aged 18–59 years); and a test-retest sample of students who completed the instruments twice within a two-week period (N = 54, 70.4% women, aged 18–47 years). The participants answered questions on gender, and age and completed the SIDAS and SBQ-R. The data analysis revealed that the Lithuanian versions of the SIDAS and SBQ-R have good internal consistency, temporal stability, construct, convergent, and criterion validity. The Lithuanian versions of the SIDAS and SBQ-R can be used to measure suicidality in research settings, as well as in clinical work as auxiliary tools.
Epidemiology of Acute Respiratory Failure in US Children: Outcomes and Resource Use
Authors: Odetola Folafoluwa O. , Gebremariam Achamyeleh 
Published: July 2024

OBJECTIVE
Acute respiratory failure recalcitrant to conventional management often requires specialized organ-supportive technologies to optimize outcomes. Variation in the availability of these technologies prompted testing of the hypothesis that outcomes and resource use will vary by not only patient characteristics but also hospital characteristics and receipt of organ-supportive technology.

METHODS
Retrospective study of children 0 to 20 years old hospitalized for acute respiratory failure using the 2019 Kids’ Inpatient Database. Multivariable regression models identified factors associated with mortality, length of hospitalization, and costs.

RESULTS
Of an estimated 75 365 hospitalizations nationally, 97% were to urban teaching hospitals, 57% were of children &lt; 6 years, and 58% were of males. Complex chronic conditions (CCC) existed in 62%, multiorgan dysfunction in 35%, and extreme illness severity in 54%. Mortality was 7%, length of stay 15 days, and hospital costs $77 168. Elevated mortality was associated with cumulative organ dysfunction (odds ratio [OR]:2.31, 95% confidence interval [CI]: 2.22–2.42), CCC (OR: 5.49, 95% CI: 4.73–6.37), transfer, higher illness severity, and cardiopulmonary resuscitation. Lower mortality was associated with extracorporeal membrane oxygenation (OR: 0.36, 95% CI: 0.28–0.47) and new tracheostomy (OR: 0.30, 95% CI: 0.25–0.35). Longer hospitalization was associated with transfer, infancy, CCC, higher illness severity, cumulative organ dysfunction, and urban hospitals. Higher costs accrued with noninfants, cumulative organ dysfunction, private insurance, and urban teaching hospitals.

CONCLUSIONS
Hospitalizations for pediatric acute respiratory failure incurred substantial mortality and resource consumption. Efforts to reduce mortality and resource consumption should address interhospital transfer, access to organ-supportive technology, and drivers of higher severity-adjusted resource consumption at urban hospitals.
Pediatric Device Clinical Trials Activity: 1999–2022
Authors: Dienstman Joshua , Stachelek Stanley J. , Krieger Abba M. , Eskandanian Kolaleh , Espinoza Juan C. , Harrison Michael R. , Koh Chester J. , Peiris Vasum , Torjusen Erika , Levy Robert J. 
Published: July 2024

OBJECTIVES
This study assessed the state of pediatric medical device (PMD) development by comparing PMD clinical trials to pediatric trials evaluating drugs and biologics, from 1999 to 2022.

METHODS
The site www.clinicaltrials.gov was used to identify and quantify both PMD clinical trials and pediatric trials for drugs and biologics. Clinical specialty was also assessed. The institutions included were the 7 children’s hospitals primarily affiliated with the Food and Drug Administration (FDA) Pediatric Device Consortia (PDC) grant program between 2018 and 2023. For a national comparison, an additional search assessed PMD trials across all US medical institutions.

RESULTS
A total of 243 PMD clinical trials were identified at the FDA–PDC institutions on the basis of the year of initiation; the average number of PMD trials initiated per year per institution was 1.5 from 1999 to 2022. However, PMD trials significantly increased during the period 2014 to 2022 compared with 1999 to 2013 (P &lt; .001); the rate of initiation of drug and biologic pediatric trials demonstrated no significant differences between these time periods. A national survey of all institutions initiating PMD trials, and drugs and biologics trials, identified 1885 PMD trials out of a total 12 943. A comparable trend was noted in the national survey with initiation of PMD trials increasing significantly from 2014 to 2022 (P &lt; .001), compared with 1999 to 2013, whereas the rate of initiation of drug and biologic trials during these periods did not demonstrate a significant change.

CONCLUSIONS
Although pediatric clinical trial initiation for drugs and biologics remained stable from 1999 to 2022, the rate of new PMD trials significantly increased during the period 2014 to 2022 at FDA–PDC institutions and nationally.