bluuebunny/crossref_metadata_2025_split huggingface dataset:
Transcriptomics and metabolomics reveal the mechanism of metabolites changes in Cymbidium tortisepalum var. longibracteatum colour mutation cultivars
Authors: Jiang Yu , Liu Yaqin , Lin Yang , Tu Xunliang , He Junrong 
Published: June 2024

Background
Foliage color is considered an important ornamental character of Cymbidium tortisepalum (C. tortisepalum), which significantly improves its horticultural and economic value. However, little is understood on the formation mechanism underlying foliage-color variations.

Methods
In this study, we applied a multi-omics approach based on transcriptomics and metabolomics, to investigate the biomolecule mechanisms of metabolites changes in C. tortisepalum colour mutation cultivars.

Results
A total of 508 genes were identified as differentially expressed genes (DEGs) between wild and foliage colour mutation C. tortisepalum cultivars based on transcriptomic data. KEGG enrichment of DEGs showed that genes involved in phenylalanine metabolism, phenylpropanoid biosynthesis, flavonoid biosynthesis and brassinosteroid biosynthesis were most significantly enriched. A total of 420 metabolites were identified in C. tortisepalum using UPLC-MS/MS-based approach and 115 metabolites differentially produced by the mutation cultivars were identified. KEGG enrichment indicated that the most metabolites differentially produced by the mutation cultivars were involved in glycerophospholipid metabolism, tryptophan metabolism, isoflavonoid biosynthesis, flavone and flavonol biosynthesis. Integrated analysis of the metabolomic and transcriptomic data showed that there were four significant enrichment pathways between the two cultivars, including phenylalanine metabolism, phenylpropanoid biosynthesis, flavone and flavonol biosynthesis and flavonoid biosynthesis.

Conclusion
The results of this study revealed the mechanism of metabolites changes in C. tortisepalum foliage colour mutation cultivars, which provides a new reference for breeders to improve the foliage color of C. tortisepalum.
Effect of intravenous palonosetron on hypotension induced by spinal anesthesia for cesarean section: A randomized controlled trial
Authors: Kim Min Kyoung , Kim Injeong , Kang Hyun , Wi Wongook , Park Yong Hee , Jung Yong Hun , Woo Young Cheol , Baek Chong Wha 
Published: June 2024

Background
The aim of this study was to evaluate the impact of intravenous palonosetron compared to ondansetron on hypotension induced by spinal anesthesia in women undergoing cesarean section.

Methods
Fifty-four women scheduled for elective cesarean section were, randomly allocated to ondansetron group (n = 27) or palonosetron group (n = 27). Ten minutes prior to the administration of spinal anesthesia, participants received an intravenous injection of either ondansetron or palonosetron. A prophylactic phenylephrine infusion was initiated immediately following the intrathecal administration of bupivacaine and fentanyl. The infusion rate was titrated to maintain adequate blood pressure until the time of fetal delivery. The primary outcome was total dose of phenylephrine administered. The secondary outcomes were nausea or vomiting, the need for rescue antiemetics, hypotension, bradycardia, and shivering. Complete response rate, defined as the absence of postoperative nausea and vomiting and no need for additional antiemetics, were assessed for up to 24 hours post-surgery.

Results
No significant differences were observed in the total dose of phenylephrine used between the ondansetron and palonosetron groups (387.5 μg [interquartile range, 291.3–507.8 μg versus 428.0 μg [interquartile range, 305.0–507.0 μg], P = 0.42). Complete response rates also showed no significant differences between the groups both within two hours post-spinal anesthesia (88.9% in the ondansetron group versus 100% in the palonosetron group; P = 0.24) and at 24 hours post-surgery (81.5% in the ondansetron group versus 88.8% in the palonosetron group; P = 0.7). In addition, there was no difference in other secondary outcomes.

Conclusion
Prophylactic administration of palonosetron did not demonstrate a superior effect over ondansetron in mitigating hemodynamic changes or reducing phenylephrine requirements in patients undergoing spinal anesthesia with bupivacaine and fentanyl for cesarean section.
Advances in dissolved oxygen prediction and control methods in aquaculture: a review
Authors: Li Daoliang , Yang Jianan , Bai Yu , Du Zhuangzhuang , Wang Cong 
Published: June 2024

Abstract
In the aquaculture industry, maintaining stable levels of dissolved oxygen (DO) is crucial for ensuring the health of aquatic organisms and enhancing farming efficiency. This article delves into the challenges faced in predicting and controlling DO levels, such as the need for real-time monitoring and response, the complexity of systems, and limitations in technology and resources. The paper comprehensively reviews various methods for DO prediction and control, including mechanistic modeling prediction, machine learning techniques, and both classical and intelligent control strategies. It analyzes their advantages, limitations, and applicability in aquaculture environments. Through this review and analysis, the article provides more comprehensive insights and guidance for future research directions in DO prediction and control in aquaculture.
Integration of selected AI methods into a simulation tool for urban wastewater systems – towards practical application
Authors: Ogurek Michael , Alex Jens , Schütze Manfred 
Published: June 2024

Abstract
State-of-the-art modelling tools and dynamic simulations have become important tools for planning and operational decision making in the environmental sector, including wastewater treatment plants. Due to increasing regulatory requirements (energy savings, treatment performance, GHG footprint), the practical application of these instruments is becoming more challenging. AI methods could be a solution to support users in the application of domain-specific modelling and simulation tools. This contribution presents first steps towards the integration of the AI methods Bayesian Networks (BN) and Artificial Neural Networks (ANN) into a modelling and simulation tool for urban waste water systems, including example applications.
Probabilistic multi-step ahead streamflow forecast based on deep learning
Authors: Karimanzira Divas , Richter Lucas , Hilbring Desiree , Lödige Michaela , Vogl Jonathan 
Published: June 2024

Abstract
The use of deep learning methods for fluvial flood forecasting is rapidly gaining traction, offering a promising solution to the challenges associated with accurate yet time-consuming numerical models. This paper presents two physics-inspired deep learning approaches specifically designed for fluvial flood forecasting, each embracing different learning principles: centralized and federated learning. The centralized model utilizes an Encoder-Decoder technique to handle input data of varying types and scales, while the federated model is based on a node-link graph with a seq2seq internal model. Both models are enhanced with a probabilistic forecasting head to account for the inherent uncertainty in streamflow forecasts. The objective of these approaches is to address the limitations of traditional numerical models while leveraging the potential of deep learning to improve the speed, accuracy, and scalability of flood forecasting. To validate their effectiveness, the models were tested across different use cases. The findings from the federated learning approach emphasize the importance of catchment clustering before model utilization and demonstrate the models’ ability to generalize effectively in catchments with similar properties. On the other hand, the results of the centralized method highlight the model’s reliance on the test set falling within the data range of the training set (Average NSE and KGE for the sixth hour ahead of 0.88 and 0.78, respectively). To address this limitation, the paper suggests the development of a method for the future, such as leveraging a numerical model or using Generative Adversarial Networks, to generate highly extreme events, particularly in the context of a changing climate. The models are implemented in a flexible operational framework based on open standards, ensuring their adaptability and usability in various settings.
NiMo 4.0 – Enabling advanced data analytics with AI for environmental governance in the water domain
Authors: Budde Matthias , Hilbring Desiree , Vogl Jonathan , Dittmar Daniel , Abecker Andreas 
Published: June 2024

AbstractIn the realm of environmental governance, civil servants confront a plethora of diverse datasets, including time series, geospatial vector data, and raster data. However, unlocking the transformative potential of Artificial Intelligence (AI) models to analyze this data poses the challenge of a widening technical proficiency gap in public administration. This paper explores the intersection of expanding environmental datasets and advanced analytics. Through a real-world project lens, our work aims to guide public administration entities, fostering seamless integration of AI-driven analytics and data-driven decision-making. We present a modular technical architecture that proposes pragmatic solutions that have the potential to empower civil servants. This approach contributes to accelerating environmental governance into an era of more informed and efficient, data-driven practices.
The correlation between serum angiopoietin-2 levels and acute kidney injury (AKI): a meta-analysis
Authors: Zhang Juncheng , Huang Zhengjie , Lin Qin , Hu Weiping , Zhong Hongbin , Zhang Fengling , Huang Jiyi 
Published: June 2024

Abstract

Introduction
The correlation between serum angiopoietin-2 levels and acute kidney injury (AKI) is a topic of significant clinical interest. This meta-analysis aims to provide a comprehensive evaluation of this relationship.

Content
A systematic search was conducted in PubMed, Embase, Web of Science, and Cochrane databases up to October 11, 2023. The included studies were evaluated using the Newcastle-Ottawa Scale (NOS) and Methodological Index for Non-Randomized Studies (MINORS). Weighted mean differences (WMD) and odds ratios (OR) were calculated using random-effects models. Sensitivity analysis, funnel plots, and Egger’s test were used to assess the robustness and publication bias of the findings. Subgroup analyses were performed to explore potential variations between adults and children.

Summary
Eighteen studies encompassing a total of 7,453 participants were included. The analysis revealed a significant elevation in serum angiopoietin-2 levels in patients with AKI compared to those without (WMD: 4.85; 95 % CI: 0.75 to 0.27; I²=93.2 %, p<0.001). Subgroup analysis indicated significantly higher angiopoietin-2 levels in adults with AKI (WMD: 5.17; 95 % CI: 3.51 to 6.83; I²=82.6 %, p<0.001), but not in children. Additionally, high serum angiopoietin-2 levels were associated with an increased risk of AKI (OR: 1.58; 95 % CI: 1.39 to 1.8; I²=89.1 %, p<0.001). Sensitivity analysis validated the robustness of these results, showing no substantial change in the overall effect size upon the exclusion of individual studies.

Outlook
This meta-analysis supports a significant association between elevated serum angiopoietin-2 levels and increased risk of AKI. The observed differential association between adults and children highlights the need for further targeted research to understand these age-specific variations.
Time Truncated Attribute Median Control Charts for Logistic-Exponential Process Distribution
Authors: Saha Mahendra , Pareek Pratibha , Maheshwari Sparsh , Pandey Arvind 
Published: June 2024

Abstract
In this article, time truncated attribute control chart is proposed for logistic-exponential distribution based on four acceptance sampling plans. The performance of the proposed control chart is evaluated in terms of average run length. Furthermore, the efficiency of the proposed attribute control chart is compared for all given acceptance sampling plans, viz., single sampling plan, repetitive sampling plan, multiple dependent state sampling plan and multiple dependent state repetitive sampling plan. Also, the application of the proposed control chart is illustrated by using real life example.
Ageing Concepts for Bivariate Copulas
Authors: Unnikrishnan Nair N. , Sunoj S. M. 
Published: June 2024

Abstract
In the present work we first discuss the structure and properties of the ageing function of the Gumbel–Barnett copula in the exchangeable case. Then we define and illustrate the ageing notions such as IFR, DMRL, NBU etc for copulas using the weak copula ageing property of the Gumbel–Barnett copula.
Birational equivalence of the Zassenhaus varieties for basic classical Lie superalgebras and their purely-even reductive Lie subalgebras in odd characteristic
Authors: Shu Bin , Zheng Lisun , Ren Ye 
Published: June 2024

Abstract
Let

𝔤
=

𝔤

0
¯

⊕

𝔤

1
¯

{{\mathfrak{g}}={\mathfrak{g}}_{\bar{0}}\oplus{\mathfrak{g}}_{\bar{1}}}

be a basic classical Lie superalgebra over an algebraically closed field

𝐤

{{\mathbf{k}}}

of characteristic

p
>
2

{p>2}

. Denote by

𝒵

{\mathcal{Z}}

the center of the universal enveloping algebra

U
⁢

(
𝔤
)

{U({\mathfrak{g}})}

. Then

𝒵

{\mathcal{Z}}

turns out to be finitely-generated purely-even commutative algebra without nonzero divisors.
In this paper, we demonstrate that the fraction

Frac
⁡

(
𝒵
)

{\operatorname{Frac}(\mathcal{Z})}

is isomorphic to

Frac
⁡

(
ℨ
)

{\operatorname{Frac}(\mathfrak{Z})}

for the center

ℨ

{\mathfrak{Z}}

of

U
⁢

(

𝔤

0
¯

)

{U({\mathfrak{g}}_{\bar{0}})}

. Consequently, both Zassenhaus varieties for

𝔤

{{\mathfrak{g}}}

and

𝔤

0
¯

{{\mathfrak{g}}_{\bar{0}}}

are birationally equivalent via a subalgebra

𝒵
~

⊂
𝒵

{\widetilde{\mathcal{Z}}\subset\mathcal{Z}}

, and

Spec
⁡

(
𝒵
)

{\operatorname{Spec}(\mathcal{Z})}

is rational under the standard hypotheses.
On Strichartz estimates for many-body Schrödinger equation in the periodic setting
Authors: Huang Xiaoqi , Yu Xueying , Zhao Zehua , Zheng Jiqiang 
Published: June 2024

Abstract
In this paper, we prove Strichartz estimates for many body Schrödinger equations in the periodic setting, specifically on tori

𝕋
d

{\mathbb{T}^{d}}

, where

d
≥
3

{d\geq 3}

. The results hold for both rational and irrational tori, and for small interacting potentials in a certain sense. Our work is based on the standard Strichartz estimate for Schrödinger operators on periodic domains, as developed in [J. Bourgain and C. Demeter,
The proof of the

l
2

l^{2}

decoupling conjecture,
Ann. of Math. (2) 182 2015, 1, 351–389]. As a comparison, this result can be regarded as a periodic analogue of [Y. Hong,
Strichartz estimates for N-body Schrödinger operators with small potential interactions,
Discrete Contin. Dyn. Syst. 37 2017, 10, 5355–5365] though we do not use the same perturbation method. We also note that the perturbation method fails due to the derivative loss property of the periodic Strichartz estimate.
On corrected Simpson-type inequalities via local fractional integrals
Authors: Lakhdari Abdelghani , Meftah Badreddine , Saleh Wedad 
Published: June 2024

Abstract
The paper discusses corrected Simpson-type inequalities on fractal sets. Based on an introduced identity, we establish some error bounds for the considered formula using the generalized s-convexity and s-concavity of the local fractional derivative. Finally, we present some graphical representations justifying the established theoretical framework as well as some applications.
A class of nontrivial simple examples of a non-D-space
Authors: Chou Yu-Lin 
Published: June 2024

Abstract
Given any regular

T
0

{T_{0}}

(equivalently, regular

T
1

{T_{1}}

) space X, the question of whether X being Lindelöf implies X being a D-space is an active open problem.
This article gives a class of handy examples of a second countable collectionwise normal collectionwise Hausdorff

T
0

{T_{0}}

space of uncountable cardinal,
with at most countably many singletons being not closed,
that is not a D-space.
Also given is a class of handy examples of a second countable hyperconnected

T
0

{T_{0}}

space of uncountable cardinal,
with at most countably many singletons being not closed,
that is not a D-space.
Registry or randomization – must it be evidence or could it be coincidence?
Authors: Radulova Olga , Oehme Florian , Korn Sandra , Praetorius Christian , Distler Marius , Weitz Jürgen 
Published: June 2024

Abstract
Over the years, clinical registries and randomized controlled trials gained acceptance. With increasing experience, it was possible to obtain knowledge of benefits and limitations in both designs. During the last years, the research focus was placed on new study concepts such as register-based randomized controlled trials intending to merge the benefits of evidence obtained by RCTs and clinical registers. In this review, we aim to provide an overview of the evolution and the present stage of clinical trials. While doing so, we outline past experience and look ahead toward improving models for high-quality clinical trials.
A simple approach for studying stability properties of an SEIRS epidemic model
Authors: Hoang Manh Tuan 
Published: June 2024

Abstract
In this work, we study stability properties of a well-known integer-order SEIRS model with nonlinear incidence and vertical transmission. Firstly, we introduce a simple approach to the analysis of global asymptotic stability (GAS) of the integer-order model. This approach is based on general quadratic Lyapunov functions and characteristic of quadratic forms associated with real matrices. The result is that the GAS of disease-free and disease-endemic equilibrium points is completely established. This provides an important improvement for results constructed in two previous works. Secondly, we generalize the integer-order SEIRS model by considering it in the context of the Caputo fractional-order derivative. After that, the present approach is utilized to investigate the GAS of the proposed fractional-order model. As an important consequence, not only the GAS but also the uniform stability of the fractional-order model are determined fully. Therefore, the applicability of the approach is shown. Finally, a series of numerical experiments is conducted to illustrate and support the theoretical findings.
Long-term functional outcomes and predictors of efficacy in thulium laser enucleation of the prostate (ThuLEP) for benign prostatic hyperplasia (BPH): a retrospective observational study
Authors: Spirito Lorenzo , Capra Massimo , Sciorio Carmine , Romano Lorenzo , Morelli Michele , Valtorta Adelio , Arcaniolo Davide , Mirto Benito Fabio , Manfredi Celeste , Sicignano Enrico , Capone Federico , Giampaglia Gaetano , Iaconis Salvatore , Napolitano Luigi , Machiella Fabio , Quattrone Carmelo , Imperatore Vittorio , Crocetto Felice 
Published: June 2024

Abstract

Objectives
Benign prostatic hyperplasia (BPH) is a common urological condition affecting aging men worldwide. Among the treatment options available for BPH, transurethral resection of the prostate (TURP) is the gold-standard invasive intervention. To reduce the TURP-related non-negligible morbidity, loss-of-ejaculation rate, hospitalization, blood loss and catheterization time several laser techniques have been developed, such as the Thulium Laser Enucleation of the Prostate (ThuLEP). To investigate the efficacy outcomes of the ThuLEP as a treatment option for benign prostatic hyperplasia (BPH) we performed a retrospective observational study at Moriggia Pelascini Hospital (Como, Italy) between January 2015 and September 2018.

Methods
We included 265 patients who underwent ThuLEP at a specific hospital between defined dates. Data on various parameters, including post-void residue volume, peak urinary flow rate (Qmax), International Prostate Symptom Score (IPSS) for urinary symptoms, IPSS Quality of Life (QoL) score, and International Index of Erectile Function (IIEF) score for erectile dysfunction, were collected at baseline and follow-up.

Results
The analysis revealed significant improvements in voiding efficiency, urinary flow, urinary symptoms, quality of life, and erectile function following ThuLEP. Furthermore, certain baseline characteristics, such as post-void residue, peak urinary flow rate, age, prostate volume, and aspirin usage, were found to influence treatment outcomes.

Conclusions
Despite the study’s limitations, these findings contribute to understanding ThuLEP’s effectiveness in managing BPH and can aid in making informed clinical decisions for patient care. Prospective studies with longer follow-up periods are recommended to validate and extend these results.
Effects of infill pattern and compression axis on the compressive strength of the 3D-printed cubic samples
Authors: Kamer Muhammed S. , Dogan Oguz 
Published: June 2024

Abstract
Structures that are very difficult to produce with classical manufacturing methods have become easily produced with the development of additive manufacturing (AM) technique. AM technique allows creating special infill patterns with gaps in the internal structures of the products to be produced. These special infill patterns ensure that the product has maximum rigidity and strength while also providing minimum mass. For this reason, it is important to investigate the effects of infill patterns produced by AM technique on the mechanical properties of the product. In this study, the compression characteristics of compression test samples produced in five different infill patterns (octet, grid, cubic, quarter cubic, gyroid) using the AM method were experimentally investigated in three different axes. Test samples were produced from PLA material with a 3-dimensional (3D) printer in accordance with the ASTM C365-16 standard. Compression tests were repeated three times at a compression speed of 0.5 mm/min, with five different infill patterns and three different axes for each parameter. According to the results obtained, the octet infill pattern provided the best compressive strength in all three axes. It has been determined that the infill pattern or load axis change greatly affects the compression performance of the product.
African Early Career Chemists Workshop & 8th Annual Symposium of the American Chemical Society, Nigeria International Chapter 2023
Authors: Offiong Nnanake-Abasi O. , Inyangudoh Akwaowo I. 
Published: June 2024

Abstract
This preface introduces the proceedings of the African Early Career Chemists Workshop & 8th Annual Symposium of the American Chemical Society (ACS), Nigeria International Chapter, which was held both virtually and onsite from June 4th to 8th, 2023. This special issue of Pure and Applied Chemistry (PAC) journal includes 8 manuscripts covering a range of topics from pure to applied chemistry.
Reassessing the evidence on factor and portfolio premia
Authors: Jach Agnieszka , Antell Jan 
Published: June 2024

Abstract
Using the modelling and estimation framework of W. Cao, C. Hurvich and P. Soulier (2017), we perform a test of the mean (

T
2

{T_{2}}

statistic) for a large collection of daily Fama–French factors and portfolio returns, and compare the results with those based on the standard t test. The

T
2

{T_{2}}

-based results provide clearly weaker evidence in favor of various premia and in some cases suggest their absence. On the US market, the discrepancy between the tests is particularly large for the momentum factor.
Caution should be exercised when assessing the presence of a given premium with the t test.