bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rapid DNA barcoding‐based fern and lycophyte inventories of protected areas—A pilot study to introduce a simple but effective protocol
Authors: Liu Hongmei , Chai Yarong , Schneider Harald 
Published: July 2024

AbstractRecording inventories of species conserved in protected areas is a key step to evaluate the effectiveness of Kunming Montreal Global Biodiversity Framework (KM‐GBF) targets, such as the expansion of protected areas. The application of DNA barcoding facilitates the rapid production of enables to obtain rapid inventories with reduced reliance on taxon experts. These inventories aim not only to confirm existing records but also to minimize gaps in our knowledge of the distribution and taxonomy of species targeted for conservation through the implementation of protected areas. This pilot study introduces a simplified DNA barcoding pipeline as a reliable tool for recording fern and lycophyte species occurring in protected areas. The pipeline emphasizes limited and/or short training requirements, reducing the input required from taxon experts and maximizing shared benefits between conservationists and taxonomists. Despite using a single DNA barcoding region, 78% of the accessions were unambiguously identified to the species level. This applied approach not only confirmed previous records but also identified several previously overlooked species, either as newly recorded species conserved in the protected area or as species new to science. The pilot project effectively documented known species diversity and identified gaps in our taxonomic knowledge by discovering previously unknown and locally rare taxa. This rapid assessment enhances productive exchanges between conservation practitioners and taxon experts, with substantial benefits for both parties.
Factor timing in the Chinese stock market
Authors: Wu Yuxiao 
Published: July 2024

AbstractI conduct an exploratory study about the feasibility of factor timing in the Chinese stock market, covering 24 representative and well‐identified risk factors in 10 categories from the literature. The long–short portfolio of short‐term reversal exhibits strong out‐of‐sample predictability, which is robust across various models and all types of predictors. This predictability is significant both statistically and economically, with a simple investment strategy obtaining its return three times higher than the buy‐and‐hold return in the sample period and a significant annualized 20.4% CH‐3 alpha. Portfolio historical volatility and market volatility measurement predictors play crucial roles in the reversal factor premium's robust predictability. However, such results are not evident in predicting all other factors' long–short portfolios as well as all factors' long‐wing and short‐wing portfolios, and this failure cannot be attributed to their exposure to unpredictable market returns.
Comparing video feedback and video modeling plus video feedback for improving soccer skills
Authors: Martinez Samantha K. , Miltenberger Raymond G. , Deshmukh Shreeya S. 
Published: July 2024

AbstractThis study compared the effects of video feedback (VF) as a stand‐alone intervention and video modeling plus video feedback (VMVF) for improving soccer players' static ball control skills. Research has suggested that VF alone and VMVF produce substantial improvements for young athlete's skills, though no studies have compared the two. Therefore, we used a multiple‐baseline‐across‐participants design with embedded alternating treatments to compare VF and VMVF. Two 10‐year‐old female soccer players and one 9‐year‐old male soccer player participated. The first author implemented the VF and VMVF training procedures and assessed the same three target behaviors across participants. The results suggested that VF and VMVF produced similar increases in performance for two of three participants and that VMVF produced slightly greater increases for one participant. In addition, both interventions were effective at substantially improving ball control skills from baseline levels and relative to a control skill.
Self‐disgust mediates the effect of problematic mobile social media use on non‐suicidal self‐injury in adolescents: A latent growth curve analysis
Authors: Shen Yunhong , Guo Jiaqi , Wang Chuhan , Huang Zixi , Yi Yuzhe , You Jianing 
Published: July 2024

AbstractObjectivePrevious research linked problematic mobile social media use to non‐suicidal self‐injury (NSSI). However, little research explored the underlying mechanism. Drawing on the social displacement hypothesis, which suggests that excessive social media use may disrupt offline social interactions, leading to negative emotional experiences, the study employs a longitudinal design to explore the relationship between problematic mobile social media use and NSSI, with a specific emphasis on the mediating role of self‐disgust.MethodsA total of 1,684 Chinese adolescents (52.3% females; Mage = 14.59 years, SDage = 1.27) completed self‐report questionnaires regarding problematic mobile social media use, self‐disgust, and NSSI. The assessment was conducted in three waves, 6 months apart.ResultsUsing latent growth curve and structural equation modeling, our study observed a consistent linear decline in NSSI levels over time. Higher initial NSSI levels correlated with a slower reduction. Problematic mobile social media use positively influenced the initial level of NSSI. Additionally, self‐disgust played a mediating role in the relationship between problematic mobile social media use and NSSI.ConclusionsThe study underscores the importance of understanding the emotional experiences behind social media use, beyond mere usage duration. By revealing the mediating role of self‐disgust, it provides new insights into the complex interplay between problematic mobile social media use and adolescent NSSI.
Selective colorimetric detection of inorganic arsenic (iAsIII) using homocysteine‐modified gold nanoparticles
Authors: Tseng Wei‐Bin , Huang Chien‐Er , Chang Huan‐Tsung 
Published: July 2024

AbstractArsenic contamination in environmental waters poses global health and environmental risks. This study addresses the urgent need for rapid, selective, and sensitive detection of inorganic arsenic (iAsIII) in environmental samples. Leveraging the unique properties of gold nanoparticles (AuNPs) and the selective binding affinity of homocysteine (Hcy), we developed a novel colorimetric sensor for iAsIII detection. Our investigation elucidates the mechanism by which Hcy modifies AuNPs, enabling the selective detection of iAsIII ions through chelation between amine and carboxyl groups, primarily with the predominant species H2AsO3− at pH 12.0. Our sensor achieves high selectivity (>10‐fold) for iAsIII amid various interfering ions commonly found in environmental samples. Furthermore, we demonstrate exceptional sensitivity in detecting iAsIII, with a low limit of detection (LOD) of 67 nM, aligning with regulatory standards for arsenic concentration in drinking water. The selectivity and sensitivity of our sensor were validated through experiments with various metal ions and real water samples. In conclusion, our study presents a comprehensive understanding of the mechanism, selectivity, and sensitivity of Hcy‐modified AuNPs in detecting iAsIII, offering a versatile nanosensor platform with significant implications for environmental monitoring and public health.
Radial force and wire structure determine the onset of covered self‐expandable metal stent migration in endoscopic ultrasound‐guided hepaticogastrostomy: Measurement of sliding‐resistance force using a porcine model
Authors: Koga Takehiko , Yamada Hiroshi , Ishida Yusuke , Tsuchiya Naoaki , Kitaguchi Takanori , Matsumoto Keisuke , Fukuyama Makoto , Kojima Norihiro , Hirai Fumihito 
Published: July 2024

AbstractBackgroundSelf‐expandable metal stent (SEMS) migration after endoscopic ultrasound‐guided hepaticogastrostomy (EUS‐HGS) is a severe complication. The migration risk could be related to the surface friction of SEMS, assumed to be affected by the wire structure and mechanical properties, including radial force (RF); however, their relevance remains unclear. This experimental study aimed to assess the mechanical properties of SEMS involved in the onset of stent migration by measuring the sliding‐resistance force (SF) as the SEMS moves through the stomach wall.MethodsThe SF of seven types of 8‐mm diameter SEMS (four braided and three laser‐cut types) and porcine stomach wall was measured with a universal testing machine. The SF of each SEMS was measured three times, and the average maximum SF (SFmax) was used for analysis. The correlation between SFmax and RF of each SEMS was evaluated.ResultsSFmax and RF showed a very strong positive correlation (r = 0.92). Compared to the regression line predictions in the scatter plots of SFmax and RF, the SFmax of laser‐cut and braided type SEMSs had positive and negative residuals, respectively.ConclusionsSelecting a laser‐cut type SEMS with a higher RF may more effectively prevent the onset of stent migration against the stomach wall in EUS‐HGS.
Japanese classification of pancreatic carcinoma by the Japan Pancreas Society: Eighth edition
Authors: Ishida Masaharu , Fujii Tsutomu , Kishiwada Masashi , Shibuya Kazuto , Satoi Sohei , Ueno Makoto , Nakata Kohei , Takano Shigetsugu , Uchida Katsunori , Ohike Nobuyuki , Masugi Yohei , Furukawa Toru , Hirabayashi Kenichi , Fukushima Noriyoshi , Yi Shuang‐Qin , Isayama Hiroyuki , Itoi Takao , Ohtsuka Takao , Okusaka Takuji , Inoue Dai , Kitagawa Hirohisa , Takaori Kyoichi , Tani Masaji , Nagakawa Yuichi , Yoshitomi Hideyuki , Unno Michiaki , Takeyama Yoshifumi 
Published: July 2024

AbstractIn 2023, the Japan Pancreas Society (JPS) published the new eighth edition of the Japanese classification of pancreatic carcinoma. We present here an excerpted version in English, based on the latest edition. The major changes in this revision are as follows: In the eighth edition of the Union for International Cancer Control (UICC), the T category was changed to be based on tumor size; however, the eighth edition of the Japanese classification retains the previous T category based on local invasion factors. Lymph nodes have been renamed, and regional lymph nodes have been defined by location. Peritoneal cytology, which was not previously included in distant metastasis (M), has now been included in the M category. Moreover, significant additions have been made regarding the pathological diagnosis of endoscopic ultrasound‐guided fine‐needle aspiration biopsy (EUS‐FNAB) and criteria for histological assessment of the effects after chemotherapy and radiation therapy. Although this classification is aimed at carcinoma originating in the pancreas, not in the bile duct or duodenum, if the differentiation of the primary organ is difficult, this classification should be applied. It is also desirable to describe tumors other than carcinoma and metastatic tumors to the pancreas in accordance with this classification.
Combined Flow‐Fluorescence in situ hybridization to HHV‐8 and EBV reveals the viral heterogeneity of primary effusion lymphoma
Authors: Stammler Romain , Vacher Lauriane , Fournier Benjamin , Lemaire Pierre , Chauvel Clémentine , Silvestrini Marc‐Antoine , Knapp Silène , de Frémont Grégoire Martin , Meignin Véronique , Salmona Maud , Legoff Jérôme , Vanjak Anthony , Dunogué Bertrand , Urbain Fanny , Lambotte Olivier , Noël Nicolas , Gérard Laurence , Oksenhendler Eric , Galicier Lionel , Latour Sylvain , Boutboul David 
Published: July 2024

AbstractPrimary effusion lymphoma (PEL) is a rare B‐cell non‐Hodgkin lymphoma associated with Kaposi Sarcoma‐associated herpesvirus (KSHV/HHV8) infection. Lymphoma cells are coinfected with Epstein‐Barr virus (EBV) in 60−80% of cases. Tools allowing a reliable PEL diagnosis are lacking. This study reports PEL diagnosis in 4 patients using a Flow‐Fluorescence in situ hybridization (FlowFISH) technique that allowed detection of differentially expressed EBV and HHV8 transcripts within the same sample, revealing viral heterogeneity of the disease. Moreover, infected cells exhibited variable expressions of CD19, CD38, CD40, and CD138. Therefore, FlowFISH is a promising tool to diagnose and characterize complex viral lymphoproliferations.
Behavioral and transcriptional effects of carnosine in the central ring ganglia of the pond snail Lymnaea stagnalis
Authors: Rivi Veronica , Caruso Giuseppe , Caraci Filippo , Alboni Silvia , Pani Luca , Tascedda Fabio , Lukowiak Ken , Blom Johanna M. C. , Benatti Cristina 
Published: July 2024

AbstractCarnosine is a naturally occurring endogenous dipeptide with well‐recognized anti‐inflammatory, antioxidant, and neuroprotective effects at the central nervous system level. To date, very few studies have been focused on the ability of carnosine to rescue and/or enhance memory. Here, we used a well‐known invertebrate model system, the pond snail Lymnaea stagnalis, and a well‐studied associative learning procedure, operant conditioning of aerial respiration, to investigate the ability of carnosine to enhance long‐term memory (LTM) formation and reverse memory obstruction caused by an immune challenge (i.e., lipopolysaccharide [LPS] injection). Exposing snails to 1 mM carnosine for 1 h before training in addition to enhancing memory formation resulted in a significant upregulation of the expression levels of key neuroplasticity genes (i.e., glutamate ionotropic receptor N‐methyl‐d‐aspartate [NMDA]‐type subunit 1—LymGRIN1, and the transcription factor cAMP‐response element‐binding protein 1—LymCREB1) in snails' central ring ganglia. Moreover, pre‐exposure to 1 mM carnosine before an LPS injection reversed the memory deficit brought about by inflammation, by preventing the upregulation of key targets for immune and stress response (i.e., Toll‐like receptor 4—LymTLR4, molluscan defense molecule—LymMDM, heat shock protein 70—LymHSP70). Our data are thus consistent with the hypothesis that carnosine can have positive benefits on cognitive ability and be able to reverse memory aversive states induced by neuroinflammation.
Removal of sodium dodecyl benzene sulfonate using bagasse fly ash and surface functionalized modified fly ash from aqueous solutions
Authors: Kumar Arun , Singh Alok Kumar , Singh Kaman , Mishra Anil , Dixit Utkarsh , Agarwal Ankita 
Published: July 2024

AbstractThis study explores the efficacy of a cost‐effective, functionalized adsorbent derived from bagasse fly ash (FA) for the removal of the surfactant sodium dodecylbenzene sulfonate (SDBS) from aqueous solutions. The raw bagasse FA underwent a modification process involving reflux with TiO2 in NaOH at 100°C for 24 h, resulting in a modified fly ash (MFA). Comparative analyses of the sorbents were conducted using scanning electron microscopy (SEM), transmission electron microscopy (TEM), powder X‐ray diffraction (pXRD), Brunauer–Emmett–Teller (BET) surface analysis, and Fourier‐transform infrared spectroscopy (FT‐IR). The surface area of the original FA was found to be 10.795 m2 g−1, which increased to 30.597 m2 g−1 postmodification. Similarly, the crystallinity of FA was initially 49.36% and enhanced to 79.70% after the modification process. The adsorption process of SDBS onto both FA and MFA were found to follow pseudo‐second‐order kinetics. Moreover, the Langmuir adsorption isotherm was the most fitting model, as evidenced by the R2 values at 298 K for SDBS‐FA (0.99) and SDBS‐MFA (0.99), both of which are remarkably close to unity. The dimensionless separation factor (RL) was determined to be less than one, indicating favorable adsorption. The maximum adsorption capacities predicted by the Langmuir model are 156.00 mg/g for FA and a notably higher 231.48 mg/g for MFA. Thermodynamic analysis revealed a positive change in enthalpy (ΔHo) for SDBS‐FA and SDBS‐MFA of 54.50 and 124.48 KJ mol−1, respectively, suggesting endothermic adsorption. Additionally, the Gibbs free energy (ΔGo) was negative for both SDBS‐FA and SDBS‐MFA, suggesting that the adsorption of SDBS is spontaneous.
Quality of life following pelvic exenteration in neoplasms
Authors: Zanatto Renato Morato , Mucci Samantha , Pinheiro Rodrigo N. , de Oliveira Junea Caris , Nicolau Ulisses Ribaldo , Domezi João Paulo , Silva Dárcia Lima e , Pracucho Eduardo Marcucci , Zanatto Daniela Ogawa , Saad Sarhan Sydney 
Published: July 2024

AbstractBackgroundPelvic exenteration (PE) is an extensive surgical treatment reserved for advanced or recurrent pelvic neoplasms, with potential impacts on patients' quality of life (QoL) poorly referenced in the literature.ObjectivesThis study aimed to evaluate QoL outcomes among three types of PE.MethodsA cross‐sectional study assessed 106 patients divided into anterior PE (APE), posterior PE (PPE), or total PE (TPE) groups. QoL was measured using e short form 36 version 2 (SF‐36) and the European Organization for Research and Treatment of Cancer QoL Quality of Life Questionnaire Core 30 (QLQ‐C30) QoL questionnaires. Descriptive and inferential analyses compared questionnaire scores.ResultsThe findings unveiled a balance among the three groups concerning demographic variables and comorbidities, with the exception of a male predominance in the APE and TPE cohorts. Notably, the APE group exhibited elevated scores in overall health (assessed via SF‐36) and social functioning and diarrhea domains (assessed via QLQ‐C30). Moreover, in terms of the fatigue and nausea/vomiting domains (assessed via QLQ‐C30), the APE group demonstrated superior QoL compared to the PPE group. Conversely, the PPE group manifested a notably lower QoL in the constipation domain (assessed via QLQ‐C30) compared to the other two groups. Additionally, disease recurrence was significantly associated with diminished QoL across multiple domains.ConclusionAPE patients exhibited better QoL than PPE and TPE groups, with disease recurrence adversely affecting QoL.
Impact of Nutritional Status on COVID‐19‐Induced Olfactory Dysfunction
Authors: Mastoloni Elizabeth M. , French Evan , Coelho Daniel H. ,   the N3C consortium
Published: July 2024

ObjectiveAlthough olfactory dysfunction is one of the most common presenting signs of COVID‐19 infection, little is known about which populations are most susceptible. The aim of this study is to evaluate the risk of COVID‐19‐induced chemosensory dysfunction in malnourished individuals.MethodsThe N3C database was queried for adults having positive COVID‐19 test result, diagnosis of chemosensory dysfunction within 2 weeks of positive test date, and overnutrition or undernutrition (i.e., deficiency or excess of micro‐ and macronutrients) related diagnoses prior to COVID‐19 infection. Individuals previously diagnosed with chemosensory dysfunction were excluded. COVID‐19‐positive adults without olfactory dysfunction were similarly analyzed. Statistical analysis was performed using odds ratio calculations (95% confidence interval [CI]).ResultsOf 3,971,536 patients with COVID‐19, 73,211 adults were identified with a diagnosis of undernutrition and 428,747 adults were identified with a diagnosis of overnutrition prior to infection. Of those with undernutrition, 264 (0.36%) individuals were identified with a diagnosis of olfactory dysfunction within 2 weeks of infection. Of those with overnutrition, 2851 (0.66%) individuals were identified with a diagnosis of olfactory dysfunction within 2 weeks of infection. The calculated odds ratio for undernutrition and olfactory dysfunction was 0.731 (p < 0.0001, 95% CI [0.0647, 0.0825]). The calculated odds ratio for overnutrition and olfactory dysfunction was 1.419 (p < 0.0001, 95% CI [1.3359, 1.5081]).ConclusionOvernutrition may increase the risk of COVID‐19‐related olfactory dysfunction, while undernutrition may slightly protect. While reasons are unclear, baseline differences in metabolic, inflammatory, and structural biochemistry deserve closer inspection.Level of Evidence3 Laryngoscope, 134:4338–4343, 2024
Unveiling the Bounty: A Systematic Synthesis of Biodiversity and Ecosystem Services in Mediterranean Lentil and Chickpea Cultivation Through Alternative Pulse Systems
Authors: Vollheyde Anna‐Lena , Cebrián‐Piqueras Miguel A. , von Haaren Christina 
Published: July 2024

ABSTRACTPulses get increasing awareness not only for their nutritional value but also for their multifunctionality in sustainable agri‐food systems. Although having a long tradition in Mediterranean regions, their share of arable land is very low. Knowledge about pulse cropping, considering nonmarket outputs in alternative cropping systems, is scarce. To this end, we conducted a systematic literature research. We synthesized the current quantified state of knowledge about associated biodiversity in pulse systems and ecosystem services, specifically food/feed provision and soil quality, in lentil and chickpea cropping systems using alternative management practices in the Mediterranean and analysed their impact compared to conventional practices employing a meta‐analysis. As alternative practices, we considered practices frequently proposed to be sustainable and more ecologically oriented than conventional cropping. Most studies examined soil quality, especially chemical quality, followed by grain yield. Very few studies surveyed biodiversity, most of which used arable flora as an indicator. Mean lentil and chickpea grain yields were 1484.4 ± 665 kg/ha under alternative practices, and flora richness was on average 10.9 ± 4 species during the pulse phase. We found significant positive impacts of organic farming on biodiversity, no tillage on soil quality and diversified rotations on yield. In multiservice trials, no tillage tended to be synergistic for both, yield and soil quality. In conclusion, organic and conservation agriculture elements seem promising techniques for ecosystem service‐enhancing pulse management. Anyhow, the current evidence base on ecosystem service performance in alternative pulse systems is empirically not yet robust to conclude sound data‐driven management recommendations—especially with a focus on biodiversity. However, we can draw justified hypotheses that can focus future research and can be tested in the field.
Nuclear receptors behind the therapeutic effects of plant sterols on metabolism: A review
Authors: Brañes María C. , Gillet Raimundo , Valenzuela Rodrigo 
Published: July 2024

AbstractPlant sterols are known for their hypocholesterolemic action, and the molecular mechanisms behind this within the gut have been extensively discussed and demonstrated to the point that there is a degree of consensus. However, recent studies show that these molecules exert an additional umbrella of therapeutic effects in other tissues, which are related to immune function, lipid metabolism, and glucose metabolism. A strong hypothesis to explain these effects is the structural relationship between plant sterols and the ligands of a group of nuclear receptors. This review delves into the molecular aspects of therapeutic effects related with lipid and energy metabolism that have been observed and demonstrated for plant sterols, and turns the perspective to explore the involvement of nuclear receptors as part of these mechanisms.