bluuebunny/crossref_metadata_2025_split huggingface dataset:
Paradoxes, challenges, and opportunities in the context of ethical customer experience management
Authors: Velasco Carlos , Reinoso‐Carvalho Felipe , Barbosa Escobar Francisco , Gustafsson Anders , Petit Olivia 
Published: July 2024

AbstractThis article examines paradoxes, challenges, and opportunities in the context of ethical customer experience management. Central to this discussion are different stakeholders such as firms, customers, policymakers, regulators, and society at large, as well as key issues associated with them. Firms aim to design and manage compelling experiences using customer data but face challenges balancing cost, customization, ethical concerns, and fairness in customer experience management. Customers should be encouraged to reflect on whether to share personal information for customized experiences, as well as on how far their responsibility goes in ensuring critically informed decision‐making. Policymakers and regulators must integrate the views of various stakeholders into policies and guidelines that promote a healthy society. Importantly, the digitization of customer experience has given rise to unprecedented ethical concerns related to the prospect of ‘programming’ these experiences. The shrinking temporal and spatial distance between stimuli, customer action, data footprint, and tracking poses significant reflections and dilemmas for both customers and firms. In this context, it is essential to determine ethical reflections and guidelines for customer experience design and management. We argue that firms should involve customers in assessing the implications of their experiences, while policymakers should facilitate the involvement of all stakeholders (including firms, customers, regulators, academics, and NGOs) to create an ongoing, healthy dialogue. This dialogue should guide a continuing debate aimed at evaluating the implications of specific actions in customer experience management.
CREB3 suppresses hepatocellular carcinoma progression by depressing AKT signaling through competitively binding with insulin receptor and transcriptionally activating RNA‐binding motif protein 38
Authors: He Yi , Han Shenqi , Li Han , Wu Yu , Jia Wenlong , Chen Zeyu , Pan Yonglong , Cai Ning , Wen Jingyuan , Li Ganxun , Liang Junnan , Zhao Jianping , Liu Qiumeng , Liang Huifang , Ding Zeyang , Huang Zhao , Zhang Bixiang 
Published: July 2024

AbstractcAMP responsive element binding protein 3 (CREB3), belonging to bZIP family, was reported to play multiple roles in various cancers, but its role in hepatocellular carcinoma (HCC) is still unclear. cAMP responsive element binding protein 3 like 3 (CREB3L3), another member of bZIP family, was thought to be transcription factor (TF) to regulate hepatic metabolism. Nevertheless, except for being TFs, other function of bZIP family were poorly understood. In this study, we found CREB3 inhibited growth and metastasis of HCC in vitro and in vivo. RNA sequencing indicated CREB3 regulated AKT signaling to influence HCC progression. Mass spectrometry analysis revealed CREB3 interacted with insulin receptor (INSR). Mechanistically, CREB3 suppressed AKT phosphorylation by inhibiting the interaction of INSR with insulin receptor substrate 1 (IRS1). In our study, CREB3 was firstly proved to affect activation of substrates by interacting with tyrosine kinase receptor. Besides, CREB3 could act as a TF to transactivate RNA‐binding motif protein 38 (RBM38) expression, leading to suppressed AKT phosphorylation. Rescue experiments further confirmed the independence between the two functional manners. In conclusion, CREB3 acted as a tumor suppressor in HCC, which inhibited AKT phosphorylation through independently interfering interaction of INSR with IRS1, and transcriptionally activating RBM38.
Predictors of preoperative anxiety in pediatric surgical patients in Ghana: A bi‐center study
Authors: Dei‐Asamoa Richard , Fiagbe Delali , Dellor Dzifa , Osafo Joseph 
Published: July 2024

AbstractAnticipation of surgical procedures has been noted to be a major cause of anxiety, particularly in children and their parents. Preoperative anxiety in children is associated with complications before, during, and after surgery. There is therefore the need to identify predictors of preoperative anxiety in children, for early identification and development of interventions. This study aimed at determining predictors of preoperative anxiety in children. A total of 70 children with their parents, scheduled for general pediatric surgery in two teaching hospitals in Ghana, were recruited using a convenience sampling technique. Parental anxiety, perception of quality of healthcare, and preoperative anxiety in children were measured using the State Section of the State Trait Anxiety Inventory, the Pediatric Quality of Life—Healthcare Satisfaction Module, and the modified Yale Preoperative Anxiety Scale, respectively. Previous surgical experience, age and type of surgery were obtained by demographic questionnaire and hospital records. Majority of children who participated in the study were between ages 2 and 7 years (82.9%). 84.3% of parents in the study were females. Parental anxiety (β = 0.953, pp = 0.000) and perceived quality of healthcare (β = −0.257, p = 0.031) predicted preoperative anxiety in children. Older children scheduled for major surgery were more anxious in the preoperative period than younger children scheduled for major surgery (F = 6.75, p = 0.012). Comprehensive anxiety‐alleviation protocols for pediatric surgery should involve parents as well as improving perceptions of quality of healthcare.
Prozessindustrie: Von Simulation bis Pilotanlage
Authors: Chęciński Marek 
Published: July 2024

AbstractDie Konzeption eines Katalysators für die Methanolherstellung begann im Jahr 2017 auf einem leeren Blatt Papier. Bei der Entwicklung neuer Verfahren sind chemische Erfahrung und Intuition mitentscheidend.
„Das stoffliche Problem ist ernst“
Authors: Remenyi Christian 
Published: July 2024

AbstractHenning Hopf ist Organiker, GDCh‐Ehrenmitglied und ‐Altpräsident und seit Kurzem auch Primo‐Levi‐Preisträger. Wie wenige andere Wissenschaftler hat er stets einen Blick auf das große Ganze und die gesellschaftliche Aufgabe der Chemie. Ein guter Grund für die Nachrichten, ihn für dieses „Schlaglichtheft 75“ zu befragen, was war, was ist und was in Zukunft sein soll.
Chemiehistorische Gesprächsfetzen
Authors: Kunz Dieter 
Published: July 2024

AbstractWie wäre es, wenn wir zwei Chemiker auf dem Weg zum Paradies (Dantes „Göttliche Komödie“ lässt grüßen) belauschen könnten? Wie dem fiktiven Dialog unschwer zu entnehmen ist, lag ihr beruflicher Höhepunkt in der zweiten Hälfte des letzten Jahrhunderts, das Zeitgeschehen verfolgen sie aber nach wie vor mit Interesse.
Chemische Proteinsynthese/Trendbericht Biochemie 2024 (1/3)
Authors: Hartrampf Nina 
Published: July 2024

AbstractChemische Proteinsynthese: Neue Techniken in der Durchflusschemie und selektive Ligationsmethoden ermöglichen, komplexe und präzise modifizierte Peptide und Proteine für biologische Anwendungen herzustellen. Funktionelle Charakterisierung: Mit Methoden aus Mikrobiologie, chemischer Biologie und Biochemie untersuchen Forschende die molekulare Funktion bakterieller Enzyme des Mikrobioms und decken so deren Relevanz bei der Entwicklung von Darmerkrankungen auf. DNA‐Origami: Biomoleküle auf mikro‐ und nanoskopischer Ebene zu untersuchen soll helfen, neue Therapeutika zu entwickeln, herzustellen und an ihren Zielort zu bringen. Besonders die Interaktionen von Proteinen miteinander und mit Ligandenmolekülen sind dabei wichtig.
Selective electrochemical degradation of bottlebrush elastomers
Authors: Albanese Kaitlin R. , Morris Parker T. , Roehrich Brian , Read de Alaniz Javier , Hawker Craig J. , Bates Christopher M. 
Published: July 2024

AbstractWe introduce a simple synthetic strategy to selectively degrade bottlebrush networks derived from well‐defined poly(4‐methylcaprolactone) (P4MCL) bottlebrush polymers. Functionalization of the hydroxyl groups present at the terminal ends of P4MCL side chains with α‐lipoic acid resulted in bottlebrush polymers having a range of molecular weights (Mn = 45–2200 kg mol−1) and a tunable number of reactive dithiolane chain ends. These functionalized chain ends act as efficient crosslinkers due to radical ring‐opening of the dithiolane rings under UV light. The resulting redox‐active disulfide crosslinks enable mild electrochemical or chemical degradation of the SS crosslinks to regenerate the starting bottlebrush polymer. P4MCL side chains and the disulfides can be degraded simultaneously using harsher reducing conditions. This combination of bottlebrush architecture with facile disulfide crosslinking presents a versatile platform for preparing highly tunable elastomers that undergo controlled degradation under mild conditions.
Psychometric properties and measurement invariance of the Chinese version of the cognitive emotion regulation questionnaire‐short in patients with cancer
Authors: Zheng Xiaoting , Tian Xia , Zhou Xiaojun , Huang Yongqi , Xiao Wenli 
Published: July 2024

AbstractObjectiveThe study aimed to evaluate the psychometric properties and measurement invariance (MI) of the Chinese version of the cognitive emotion regulation questionnaire‐short (CERQ‐short) in cancer patients.MethodsThis cross‐sectional study included 505 cancer patients from mainland China. In addition to sociodemographic and clinical characteristics, the CERQ‐short and the distress thermometer were included in the study measures.ResultsItem analysis indicated a promising result. And the results of CFA indicated that the CERQ‐short demonstrated satisfactory factorial validity in cancer patients. Cronbach's alpha coefficients were between 0.663 and 0.910, while McDonald's omega coefficients were between 0.664 and 0.910. The CERQ‐short had sufficient convergent, discriminant and concurrent validity among cancer patients. Lastly, MI supported that the CERQ‐short demonstrated strong measurement equivalence across gender, residence and age.ConclusionsThis study shows that the Chinese version of the CERQ‐short has convincing psychometric properties and MI, which supports its use in cancer patients.
Red Fluorescence from Organic Microdots: Leveraging Foldamer‐Linked Azobenzene for Enhanced Stability and Intensity in Bioimaging Applications
Authors: Zhang Lianjin , Jeong Seoneun , Lee Jeehee , Kim Jaewook , Lee Jung Seok , Park Jihye , Hong Jungwoo , Eom Jae‐Hoon , Kim Hyungjun , Rhee Young Min , Lee Haeshin , Lee Hee‐Seung 
Published: July 2024

AbstractAzobenzene, while relevant, has faced constraints in biological system applications due to its suboptimal quantum yield and short‐wavelength emission. This study presents a pioneering strategy for fabricating organic microdots by coupling foldamer‐linked azobenzene, resulting in robust fluorescence intensity and stability, especially in aggregated states, thereby showing promise for bioimaging applications. Comprehensive experimental and computational examinations elucidate the mechanisms underpinning enhanced photostability and fluorescence efficacy. In vitro and in vivo evaluations disclose that the external layer of cis‐azo‐foldamer microdots performs a self‐sacrificial function during photo‐bleaching. Consequently, these red‐fluorescent microdots demonstrate extraordinary structural and photochemical stabilities over extended periods. The conjugation of a β‐peptide foldamer to the azobenzene chromophore through a glycine linker instigates a blue‐shifted and amplified π*–n transition. Molecular dynamics simulations reveal that the aggregated state of cis‐azo‐foldamers fortifies the stability of cis isomers, thereby augmenting fluorescence efficiency. This investigation furnishes crucial insights into conceptualizing novel, biologically inspired materials, promising stable and enduring imaging applications, and carries implications for diverse arenas such as medical diagnostics, drug delivery, and sensing technologies.
Bimetal Oxides Anchored on Carbon Nanotubes/Nanosheets as High‐Efficiency and Durable Bifunctional Oxygen Catalyst for Advanced Zn–Air Battery: Experiments and DFT Calculations
Authors: Ruan Qi‐Dong , Zhao Yun‐Cai , Feng Rui , Haq Mahmood Ul , Zhang Lu , Feng Jiu‐Ju , Gao Yi‐Jing , Wang Ai‐Jun 
Published: July 2024

AbstractTo meet increasing requirement for innovative energy storage and conversion technology, it is urgent to prepare effective, affordable, and long‐term stable oxygen electrocatalysts to replace precious metal‐based counterparts. Herein, a two‐step pyrolysis strategy is developed for controlled synthesis of Fe2O3 and Mn3O4 anchored on carbon nanotubes/nanosheets (Fe2O3‐Mn3O4‐CNTs/NSs). The typical catalyst has a high half‐wave potential (E1/2 = 0.87 V) for oxygen reduction reaction (ORR), accompanied with a smaller overpotential (η10 = 290 mV) for oxygen evolution reaction (OER), showing substantial improvement in the ORR and OER performances. As well, density functional theory calculations are performed to illustrate the catalytic mechanism, where the in situ generated Fe2O3 directly correlates to the reduced energy barrier, rather than Mn3O4. The Fe2O3‐Mn3O4‐CNTs/NSs‐based Zn–air battery exhibits a high‐power density (153 mW cm−2) and satisfyingly long durability (1650 charge/discharge cycles/550 h). This work provides a new reference for preparation of highly reversible oxygen conversion catalysts.
Single Atom Ag Bonding Between PF3T Nanocluster and TiO2 Leads the Ultra‐Stable Visible‐Light‐Driven Photocatalytic H2 Production
Authors: Kao Jui‐Cheng , Teng Ting‐Yu , Lin Hao‐Wu , Tseng Fan‐Gang , Ting Li‐Yu , Bhalothia Dinesh , Chou Ho‐Hsiu , Lo Yu‐Chieh , Chou Jyh‐Pin , Chen Tsan‐Yao 
Published: July 2024

AbstractAtomic Ag cluster bonding is employed to reinforce the interface between PF3T nano‐cluster and TiO2 nanoparticle. With an optimized Ag loading (Ag/TiO2 = 0.5 wt%), the Ag atoms will uniformly disperse on TiO2 thus generating a high density of intermediate states in the band gap to form the electron channel between the terthiophene group of PF3T and the TiO2 in the hybrid composite (denoted as T@Ag05‐P). The former expands the photon absorption band width and the latter facilitates the core‐hole splitting by injecting the photon excited electron (from the excitons in PF3T) into the conduction band (CB) of TiO2. These characteristics enable the high efficiency of H2 production to 16 580 µmol h−1 g−1 and photocatalysis stability without degradation under visible light exposure for 96 h. Compared to that of hybrid material without Ag bonding (TiO2@PF3T), the H2 production yield and stability are improved by 4.1 and 18.2‐fold which shows the best performance among existing materials in similar component combination and interfacial reinforcement. The unique bonding method offers a new prospect to accelerate the development of photocatalytic hydrogen production technologies.
Choanal atresia: A review of surgical outcomes in a tertiary medical center
Authors: Dheyauldeen Sinan , Heimdal Ketil , Osnes Terje , Akre Harriet , Olsson Lars 
Published: July 2024

AbstractIntroductionChoanal atresia (CA) is a congenital narrowing or obliteration of the posterior nasal aperture. The condition is rare with an incidence of approximately 1 in 5000 to 9000 live births.ObjectiveThe aim of this work was to assess the results of treating this condition at the Otolaryngology Department in Oslo University Hospital‐Rikshospitalet.MethodsRetrospective review of patients treated at Oslo University Hospital‐Rikshospitalet between 2005 and 2015 were performed. The review consisted of surgical techniques and outcomes, types of atresia, uses of stent and mitomycin C, age at operation, laterality of atresia, and associated anomalies.ResultsThirty‐one patients with CA were referred to Oslo University Hospital‐Rikshospitalet during the mentioned observation period. Nine (29%) of the cases had bilateral CA and 22 (71%) had unilateral CA. Ten patients (32%) had bony atresia, 12 (39%) had membranous and eight (26%) had mixed type of atresia. Twenty‐one patients (68%) needed revision surgery because of complete or partial restenosis after primary surgery. Stents were applied in 16 cases (52%) of patients and Mitomycin C was only used in the primary surgery of three patients. In the bilateral group, eight of the nine patients were operated on within the first 9 days of life. Sixteen patients (45%) had associated anomalies.ConclusionsAccording to the observations in our sample, the restenosis problem is expected more and may need more revisions in bilateral CA than the unilateral type. The presence of other anomalies is associated with higher incidence of restenosis. Stenting is not essential in preventing restenosis.
“Sentimento do Mundo” – On the Endless Battle for a Justice System
Authors: de Werd Marc 
Published: July 2024

AbstractIn the summer of 1787, New Yorkers were about to ratify a constitution for the US. In a series of 85 essays written by Alexander Hamilton, John Jay, and James Madison between October 1787 and May 1788 urged New Yorkers to ratify the proposed United States Constitution, which was drafted in Philadelphia in the summer of 1787. The essays (commonly referred to as the Federalist Papers) were published anonymously, under the pen name “Publius,” in various New York state newspapers of the time. On May 28, 1788, Alexander Hamilton published Federalist 78, titled “The Judicial Department.” In this famous essay, he offered a powerful defense of judicial review. Hamilton argued that only a federal judge could guarantee constitutional rights and provide an effective check on state power. At the same time, Hamilton had to convince his political opponents that the unelected judiciary would never dominate the other branches of government. Drawing on the ideas of Montesquieu, he deliberately portrayed the judiciary as “the least dangerous branch of government”. A branch that is inherently weak because it can control neither the country’s financial resources nor the army.
Economic Growth & Resilience
Authors: Benczúr Péter , Kónya István 
Published: July 2024

AbstractThis chapter looks at the overall macroeconomic and social situation of the CEEE at the onset of Russia’s aggression on Ukraine and over the consecutive 18 months. Given its close proximity to the Covid-19 crisis, we interpret these shocks together as a twin crisis and draw parallels with the 2008-12 Global Financial Crisis (GFC). Unlike during the GFC, most of the CEEE seems to have recovered from the first phase (the Covid-19 shock) quickly. Under the surface, one can nevertheless discover important vulnerabilities and imbalances, in energy prices and supply security, the build-up of inflationary pressures and a decreased fiscal space. Though the status of the resilience capacities of the CEEE in early 2022 was still better than before the GFC, it was somewhat weaker than before the Covid-19 shock. Moreover, through their fossil energy imports, the CEEE had a substantial direct exposure to Russia. At the onset of the Ukraine shock, there were widespread fears of catastrophic consequences for industry, households in the winter, and further massive increases in energy prices. Such doomsday scenarios did not materialise, as European countries reacted more flexibly to both the quantity and price shock than anticipated. While in the majority of the CEEE the Ukrainian war lead to either a recession or a slowdown of the recovery from Covid, the recession is fairly shallow and seems to be mostly transitory. Overall, the main consequence of the war seems to be inflation, with a heterogeneous impact on the population. This may increase social pressures further, and coupled with increased societal polarisation, it may jeopardise the green transition. Finally, the war will have important geopolitical repercussions. With stronger geoeconomic and geopolitical competition, globalisation patterns may change, which will surely affect the CEEE that are highly integrated into the world economy.
Special representatives of complexified Kähler classes
Authors: Scarpa Carlo , Stoppa Jacopo 
Published: July 2024

AbstractMotivated by constructions appearing in mirror symmetry, we study special representatives of complexified Kähler classes, which extend the notions of constant scalar curvature and extremal representatives for usual Kähler classes. In particular, we provide a moment map interpretation, discuss a possible correspondence with compactified Landau–Ginzburg models, and prove existence results for such special complexified Kähler forms and their large volume limits in certain toric cases.
Evaluating the effects of digital stromal vascular fraction injections in systemic sclerosis patients: a retrospective study
Authors: Nietlispach Viviane , Besmens Inga S. , Jordan Suzana , Distler Oliver , Calcagni Maurizio 
Published: July 2024

Abstract

Objective
Managing hand symptoms in patients with systemic sclerosis is difficult, and the current treatments often provide only limited relief of. In 2014 a new treatment for theses patients was proposed for improving hand function, namely the digital injection of adipose tissue derived stem cells.

Methods
From 2015 to 2017 seven systemic sclerosis patients with an impaired hand function were treated with the aforesaid injections. A medical chart review was performed to collect pre- and postoperative patient specific data.

Results
Our findings indicated no significant improvement in nailfold capillaroscopic measurements or in the healing of preexisting digital ulcers. Additionally, patients reported a slight worsening in hand function after the treatment. However, we observed a decrease in the modified Rodnan skin score, which measures skin thickness Although previous research has verified the safety and feasibility of this treatment, we found no definitive evidence of its effectiveness.

Conclusion
Our results suggest that the specific conditions under which this treatment could be beneficial need to be identified through randomized controlled trials involving larger groups of patients.

Level of Evidence:
Level IV, therapeuticstudy.
Solving acoustic scattering problems by the isogeometric boundary element method
Authors: Dölz Jürgen , Harbrecht Helmut , Multerer Michael 
Published: July 2024

AbstractWe solve acoustic scattering problems by means of the isogeometric boundary integral equation method. In order to avoid spurious modes, we apply the combined field integral equations for either sound-hard scatterers or sound-soft scatterers. These integral equations are discretized by Galerkin’s method, which especially enables the mathematically correct regularization of the hypersingular integral operator. In order to circumvent densely populated system matrices, we employ the isogeometric embedded fast multipole method, which is based on interpolation of the kernel function under consideration on the reference domain, rather than in space. To overcome the prohibitive cost of the potential evaluation in case of many evaluation points, we also accelerate the potential evaluation by a fast multipole method which interpolates in space. The result is a frequency stable algorithm that scales essentially linear in the number of degrees of freedom and potential points. Numerical experiments are performed which show the feasibility and the performance of the approach.
Untersuchung einer Bronzespitze aus den Mallnitzer Tauern
Authors: Haubner Roland , Strobl Susanne 
Published: July 2024

ZusammenfassungVon einem Bergwanderer wurde 1976 auf einem Weg in den Mallnitzer Tauern eine Bronzespitze gefunden. Da die Fundstelle bei einem bekannten Römerweg lag, wurde angenommen, dass es sich um ein Römisches Artefakt handelt.Die metallographische Untersuchung ergab, dass die Bronze eine hohe Porosität aufweist, was vermutlich auf Gasentwicklung durch Sauerstoff oder Wasserstoff zurückzuführen ist. Die Spitze ist korrodiert, und das ursprüngliche Metall hat einen Sn Gehalt von etwa 4 Gew.%.Die Bronze ist dendritisch erstarrt und zeigt in den interdendritischen Bereichen geringe Cu2S Ausscheidungen. In den korrodierten Bereichen wurde eine übliche Anreicherung von Sn festgestellt.