bluuebunny/crossref_metadata_2025_split huggingface dataset:
ANN modeling of tincal ore dehydration
Authors: Kocadağistan Mustafa Engin 
Published: August 2024

Abstract
Tincal ore is a preferred material in many industrial applications, especially without water. It is important to dehydrate boron ores so that they can be used in materials engineering. For this purpose, some heat treatments must be carried out. Heat treatments are associated with additional costs. It is possible to model heat treatments using artificial intelligence methods, determine optimal process conditions and achieve the desired results with much less processing effort. In this study, a dehydration process was first carried out to dehydrate tincal ore and ANN (artificial neural networks) modeling of this process was investigated using the parameters of temperature, time and amount of ore. The possibility of achieving the desired H2O, B2O3 and Na2O concentration values in the dewatering process in the shortest time and by the shortest route was investigated using the ANN model. In the modeling, a single model was designed for the changes in concentrations and this model was trained separately for each. The result of the modeling was that the R
2 values for all three models were close to each other and were approximately 0.98. It was thus shown that the ANN method can be successfully modeled for dewatering processes.
Solitary and periodic pattern solutions for time-fractional generalized nonlinear Schrödinger equation
Authors: Zhao Meimei 
Published: August 2024

Abstract
In this study, the fractional variational iteration method using He’s polynomials is employed for constructing semi-analytical solutions of the fractional-in-time generalized nonlinear Schrödinger equation involving Jumarie’s modified Riemann–Liouville derivative. As a result, we obtain the solutions of the original problems in the forms of convergent series that are calculated easily. Our calculation results indicate that the method is quite efficient and convenient for these problems.
KPI-based standards benchmarking for the preference of different analytical approaches developed for simultaneous determination of ciprofloxacin and hydrocortisone: A SWOT case study
Authors: Nessim Christine , El Hamd Mohamed , Obaydo Reem , Saleh Sarah , Lotfy Hayam 
Published: August 2024

Abstract
This study aims to prefer the suitability of an analytical approach developed for simultaneously determining ciprofloxacin hydrochloride (CIP) and hydrocortisone (HYD) in their ear drop dosage form. The preference between the three known instruments was utilized, namely UV-spectrophotometry, reversed phase-high-performance liquid chromatography (RP-HPLC)-UV, and thin-layer chromatography (TLC)-densitometry. The instrumentational studies determined that the mathematical UV methods (utilized various manipulation designs such as the isoabsorptive point, absorbance ratio, extended ratio subtraction, ratio difference, and mean centering of ratio spectra) had linearities in the range of 2.0–14.0 and 1.0–14.0 µg·mL−1, the RP-HPLC-UV method showed a linearity range of 1.0–8.0 µg·mL−1, and the TLC-spectrodensitometric method had linearity ranges of 0.2–1.6 µg/band and 0.6–2.0 µg/band for both CIP and HYD, respectively. The analytical performance, validity, and greenness of the approaches were evaluated through the benchmarking of key performance indicator (KPI)-based standards and a SWOT (strengths, weaknesses, opportunities, and threats) analysis. The KPIs and SWOT study focused on several aspects, including (1) the selectivity and robustness of the methods, (2) sensitivity, (3) accuracy and precision, (4) applicability, (5) whiteness, (6) greenness, and (7) blueness. However, the assessment of whiteness, greenness, and blueness was conducted using well-known ecological assessment tools such as the RGB12 Algorithm, Analytical Eco-Scale, AGREE, GAPI, and Blue Applicability Grade Index. In conclusion, based on the findings, UV-spectrophotometry emerged as the most practically convenient approach. It demonstrated advantages based on the predetermined KPI-based standards. Furthermore, UV-spectrophotometry was deemed to be the most environmentally friendly option.
Erfüllung (von Geldschulden) im Digitalzeitalter
Authors: Jungmann Carsten 
Published: August 2024

Zusammenfassung
Die Vorschriften im Bürgerlichen Gesetzbuch über die Erfüllung von Geldschulden kommen ohne Bezugnahme auf Begriffe wie „Geld“ oder „gesetzliche Zahlungsmittel“ aus. Dennoch ist ihr Verständnis oftmals in entsprechenden Begrifflichkeiten verhaftet. Das führt zu Problemen bei der Beantwortung der Frage, ob moderne Zahlungsverfahren – wie SEPA-(Echtzeit-)Überweisungen, Zahlungen mit E-Geld (zum Beispiel via PayPal) oder mit E-Geld-Token (Euro-referenzierten „Stablecoins“ wie zum Beispiel STASIS EURO) und Transfers von Kryptowährungen wie Bitcoin oder in Zukunft von digitalem Zentralbankgeld (dem geplanten digitalen Euro) – auch ohne entsprechende Abrede im Valutaverhältnis und damit „automatisch“ erfüllungstauglich sind. Diese Probleme lassen sich durch eine Rückbesinnung auf den tatsächlichen (nicht begrifflich überdeterminierten) Gehalt der relevanten Normen und insbesondere dadurch vermeiden, dass die Bedeutung der Verkehrssitte für das Bewirken einer Leistung wieder in den Vordergrund gestellt wird. Mit dieser Maßgabe wird im vorliegenden Beitrag zunächst ein auf vier Voraussetzungen aufbauendes Modell zur Bestimmung der „automatischen“ Erfüllungstauglichkeit moderner Zahlungsverfahren entwickelt und dieses anschließend auf sieben solcher Verfahren angewendet.
Zentralbankverluste und leistungslose Zinseinkommen für Geschäftsbanken – ein Vorschlag zur Abschöpfung
Authors: Lucke Bernd , Meyer Dirk 
Published: August 2024

Zusammenfassung
Die Notenbanken des Europäischen Systems der Zentralbanken (ESZB) haben durch die Politik der quantitativen Lockerung gewaltige Mengen an Überschussliquidität geschaffen. Diese Überschussliquidität wird von den Geschäftsbanken der Eurozone gehalten und befindet sich derzeit überwiegend in der sog. Einlagefazilität, wo sie mit dem Einlagezins verzinst wird. Dies führt zu einem risikofreien Zinseinkommen der Geschäftsbanken, dem keine erkennbare Gegenleistung gegenübersteht. Zugleich belasten die Zinskosten die Gewinn- und Verlustrechnung der nationalen Zentralbanken (NZBs) im Eurosystem, sodass absehbar auf Jahre hinaus keine Notenbankgewinne an die nationalen Haushalte abgeführt werden können – vielmehr Verlustausweise wahrscheinlich werden. Wir schlagen vor, die leistungslosen Zinseinkommen der Geschäftsbanken ganz oder teilweise durch geldpolitisch unschädliche steuerliche Maßnahmen abzuschöpfen, um damit entweder Ausgabekürzungen entbehrlich oder Steuerentlastungen möglich zu machen.
Blunted sensitivity to expected value during risky decision making in individuals with problematic pornography use
Authors: Wang Jianfeng , Qu Shuangyi , Li Ruiyu , Tang Shaoyue , Li Hong 
Published: August 2024

AbstractBackground and aimsNeurobiological models of addiction posit that addiction manifests through an amplified salience towards addiction-associated stimuli and a diminished responsiveness to non-addiction-related incentives. However, existing research on reward processing in individuals with problematic pornography use (PPU) has primarily been limited to sexual cue reactivity.MethodsIn this event-related potential (ERP) study, we employed a risky decision-making task involving 30 individuals with PPU and 33 healthy controls (HCs) to examine the effects of PPU on non-pornographic (money) reward valuation.ResultsCompared to HCs, individuals with PPU exhibited compromised sensitivity to monetary rewards. Specifically, while the HC group demonstrated a differential response in late positive potential (LPP) amplitude to various expected value (EV) levels, this pattern was absent in the PPU group. This impairment was associated with poorer adaptive decision-making, as evidenced by PPU participants' inability to adjust risk choices based on changes in EV, leading to a propensity for riskier decisions in disadvantageous situations.Discussion and conclusionsThe findings of impaired monetary evaluation in individuals with PPU may potentially explain why they continually pursue pornographic rewards while showing insensitivity to other rewards in daily life. Consequently, treatment development strategies may prioritize improving sensitivity to non-pornographic rewards within this population.
The Hidden Recipes of Bartolomeo Sacchi
Authors: Walddon David S 
Published: August 2024

Written by Bartolomeo Sacchi, also known as Platina, De Voluptate et Valetudine was published in Venice in 1475. Divided into 10 chapters or books, the recipes appearing in the last five books have been extensively studied but the more than 160 that are spread among the the commentary on agriculture, medical and general food information in the first half of the work have received far less attention. This paper catalogues and describes these overlooked recipes and discusses some of the challenges to interpreting Renaissance recipe writing in general.
THE EFFECT OF LOW HEATING TEMPERATURES ON CASEIN WHEY PROTEINS
Authors: Yukalo V. , Datsyshyn K. , Storozh L. 
Published: August 2024

In the work, a comparative analysis of the fractional composition and resistance to thermal denaturation of proteins of two samples of casein wheys was carried out: the laboratory one, which was obtained at a temperature of 18°C, and the production one – at a temperature of 46°C. In both cases, wheys were separated after isoelectric precipitation of casein complex proteins with hydrochloric acid. Express electrophoresis in a polyacrylamide gel showed an identical qualitative composition of major and minor proteins fractions in both samples. Also, no differences were found in the relative content of the main protein fractions of wheys – β-lactoglobulin (β-lg), α-lactalbumin (α-la), serum albumin (BSA) and immunoglobulins (Ig). To compare resistance to heat denaturation, samples of laboratory and production wheys were heated and held for 5 min at temperatures from 60°C to 100°C with an interval of 5°C. The precipitate of denatured proteins was isolated by centrifugation. The concentration of proteins in the supernatant was determined spectrophotometrically and the qualitative and quantitative composition of the main protein fractions was analysed by express electrophoresis. As a result, it was established that the concentration of undenatured protein in both wheys does not coincide in the temperature range of 70–90°C. Laboratory whey proteins were more resistant to heat denaturation. Moreover, these differences can be detected only with short-term (5 min) thermal denaturation. Long-term high-temperature heating (30 min) does not allow them to be detected. Electrophoretic analysis of the relative content of the main protein fractions showed that changes in stability occur due to two fractions – β-lg and BSA. The relative concentration of these fractions in the undenatured residue from production whey is ˂ 3%, and in the residue from laboratory whey > 8% for BSA and > 24% for β-lg when heated to 90°C for 5 min. Long-term exposure of both wheys at 20°C before investigating their resistance to thermal denaturation may indicate that some of the changes in the stability of production whey proteins caused by preheating to 46°C are irreversible.
Ensino da Acessibilidade nos cursos de Arquivologia no Brasil:
Authors: Rangel Thayron , Oliveira Lucia Maria Velloso de 
Published: August 2024

Como uma condição humana que envolve várias dimensões da vida, as deficiências exigem o conhecimento e a ação dos órgãos e entidades para o atendimento das necessidades biopsicossociais e informacionais dos usuários dos produtos e serviços públicos. Nesse sentido, a acessibilidade cumpre o papel de efetivar o acesso aos documentos e informações, por meio da adoção de Tecnologias Assistivas, design universal e implementação de programas e ações institucionais que visem o ingresso e permanência nos espaços institucionais. Parte de um viés humanitário que consta em compromissos sociais inscritos em uma agenda mundial de proteção dos direitos das pessoas com deficiência como: a Agenda 2030 da Unesco e as normas ISO 26000 – Responsabilidade Social e ABNT NBR 16001 – Responsabilidade social – Sistema da gestão – Requisitos. Esta pesquisa objetiva identificar a existência ou não do interesse e da formalização do ensino da acessibilidade e das temáticas de acesso, usuários e inclusão social (temáticas relacionadas à acessibilidade) nos cursos de graduação de Arquivologia no Brasil. Para isso, utilizou-se como procedimentos metodológicos a pesquisa bibliográfica em bases de dados e periódicos da área e a pesquisa documental nos Projetos Políticos Pedagógicos (PPP) dos cursos analisados. Aponta a escassez da temática nos currículos, o que impacta a efetivação do acesso aos arquivos.
A retrospective analysis of microbiological surveillance of operation theatres
Authors: Panda Sambit Kumar , Nayak Soumya , Parida Saroj Kumar , Nayak Sidhartha , Patra Gopabandhu 
Published: August 2024

There are various infection diseases that have a significant impact on the health of the people. The healthcare associated infections are important cause of the patient morbidity and mortality. Research shows that the microbiological contamination of air and environment in the Operation Theaters (OTs) are one of the major risk factors of Surgical Site Infection (SSI). More than 10% patients admitted to acute care hospitals in the developed nations and 25% patients in developing nations got the infection, which was not presented at the time of admission. Annually, more than 1.3% patients were reported with SSI, and it caused 15000 deaths.The study aims to conduct a retrospective analysis of microbiological surveillance of operation theatresThis retrospective study analyzes the microbiological surveillance data from OTs over a period of 5 years from April 2017 up to March 2022 and was conducted at a tertiary care hospital, Odisha, India. Prior approval for the study was taken from the institute, and Ethical committee has provided the guidelines for maintaining the standard approach. For collecting the sample, two groups were defined that involve the swabbing surface and settle plate method. Moreover, a total of 4200 surface swab samples were taken from the 5 OTs of the hospital during the study. Out of these, 900 samples per OT were collected from General Surgery, Urology, Orthopedics and Ear, Nose, Throat (ENT) OTs whereas 600 samples were from Ophthalmology OT.Staphylococcus aureus count was 7 (3.2%) and Enterococcus spp. was 6 (2.7%). Moreover, the bacterial CFU/m was analyzed for identifying the level of infection through air. As per the outcome of the analysis, the count of air was ranged from 28-134 as the general is having highest count 137 and Ophthalmology was having least in OT.The study has shown that surgical site infection is a serious problem for the postoperative patients and staff members as it causes chronic illness that could lead to uncertain death. The microbiological quality of the air and surface of the OTs plays a critical role in such illness and issues to patients and staff members. However, the hospitals tries to maintain the good level of hygiene and low bacterial contamination rates on surface swabbing and CFU count per m of air within permissible limits.
Identification of vancomycin resistance in enterococcus & determination of minimal inhibitory concentration of vancomycin by E-test
Authors: Jain Swati , Jain Vikas , Jain Shweta 
Published: August 2024

Infections due to Enterococcal species is 2 prevalent cause of Nosocomial Infections in health care settings. They are crucial because to their inherent resistance to penicillins, cephalosporins, and low level aminoglycosides & their tendency to develop higher level of aminoglycoside and vancomycin resistance, which leaves few therapeutic alternatives for therapy. Isolation and identification of Enterococci with their Antibiogram & determination of Minimal Inhibitory Concentration (MIC) of Vancomycin by E-test. The antibiogram generated by Kirby Baur disc diffusion method and standard microbiological procedures were used to identify enterococcal isolates from distinct clinical samples. MIC level for Vancomycin was tested for all the isolates using E-test from BIOMERIEUX. Total of 108 isolates (62 E.faecalis and 46 E. faecium) were tested by E-test for MIC of Vancomycin, of which 40 (37.03%) (22 E.faecalis & 18 E. faecium) were Vancomycin Resistant (VRE) strains, having MIC level &#62;32 μg/ml. Nine strains out of 40 (45%) were found to have MIC &#62;256 μg/ml. The enterococcal isolates were observed to be sensitive to Linezolid (80%), Ofloxacin (74%), Amoxyclav (74%) and Cefaperazone (70%). For the Indian medical community, the rise of antibiotic resistance among Enterococcal species has been a significant concern. So this is need of present era that our laboratories must be well-equipped to report the resistance patterns displayed by enterococci in order to practise evidence-based medicine and reduce hospital acquired infections.
Serum IgE levels and absolute eosinophil counts with treatment response in patients with allergic rhinitis: A prospective study
Authors: Bhargava Anuja , Singh Saloni , Faiz S.M , Gupta Rajeev Krishna , Srivastava Sonal , Sharma Himanshu 
Published: August 2024

: Allergic rhinitis (AR) is a highly prevalent, chronic disease, with variable incidence rates. Clinically manifests as nasal discharge, congestion, nasal itching, sneezing and watery eyes. Treatment approach is based on duration and severity of symptoms. Second generation antihistamines are the drug of choice. Serum Ig E and Absolute Eosinophil Counts (AEC) have the potential to be the viable prognostic markers. The present study aims to assess the relationship of Serum IgE and AEC with treatment response in patients with allergic rhinitis.40 patients of allergic rhinitis were included in the study and were categorized into mild, moderate and severe allergic rhinitis according to ARIA guidelines. Pre-treatment sample for serum IgE and AEC was taken followed by 4 weeks of medical management according to categories. Post- treatment sample was taken and improvement assessed on the basis of fall in serum IgE and AEC levels.A total 40 patients were enrolled ranging from 14-60 years of age (mean age 28.75±11.23years) with female preponderance (52.5%). Most common presenting symptom being sneezing. Significant decline in pre-treatment AEC and serum IgE levels was observed.The findings of the study indicates that treatment response had an association with AEC and Serum IgE levels.
A follow – Up study on coping strategies and its association with relapse among alcohol dependent patients
Authors: Sangeetha A , Sudhakar S , Ilavarasan I , Kannan P P 
Published: August 2024

Alcohol consumption is a major problem in India. Alcohol dependence develops due to various factors, like individuals’ characteristics and social factors. The study was done to analyze coping strategies in relation to alcohol dependence and relapse.A follow-up study was conducted among 103 patients who attended the Psychiatry department for de – addiction treatment in a tertiary care centre in Chengalpattu, Tamil Nadu. A validated semi-structured questionnaire was used to collect details of Socio-demographic characteristics. The Severity of Alcohol Dependence Questionnaire and the Brief-COPE questionnaire were administered. The statistical analysis was done using SPSS version 20. Out of 127 participants, 24 dropped out of the study. 103 patients were followed up for a period of 6 months. At the end of the follow-up period, around 66% of patients relapsed. (N=69). About 64.1% of study participants belong to the age group of 31–50 years. Compared with their counterparts, non-relapsers were practicing adaptive coping strategies and relapsers were practicing maladaptive coping strategies (statistically significant p &#60; 0.05). Relapsers were practicing styles like Denial, Substance abuse, and self-blame more than the non-relapsed, and those differences were statistically significant (p &#60; 0.05). Nearly 55% of the relapsers had severe Alcohol Dependence when compared to non-relapsers (32.3%), and the difference was statistically significant (p &#60; 0.05). The study showed that poor coping among individuals with alcohol dependence was one of the factors contributing to relapse. Measures to improve Coping skills in de-addiction centres and Rehabilitation units will help dependent individuals to remain abstinent.
Estimating thyroid profile in women with polycystic ovarian syndrome and comparing it with healthy individuals
Authors: Naruka Montey , Usha SMR , Kshetrimayum Victoria , P Vijaylakshmi , Kumar Rupesh 
Published: August 2024

The Polycystic Ovarian Syndrome (PCOS) is considered as one of the most common endocrinopathies in women of reproductive age having the issues related to the hyperandrogenism and oligo-anovulation. The rate of prevalence in premenopausal women is between 6-10% worldwide and in India it is around 5-10%. Interaction of small number of key genes responsible for most of the endocrine and metabolic symptom with environmental risk factors have impact on high prevalence of PCOS.To analyse thyroid profile in women with polycystic ovarian syndrome and compare it with healthy individualsThe samples were collected from PCOS patientsdiagnosed according to Rotterdam criteria, ascertained by ultrasonography, attending the OPD in the department of Obstetrics and Gynecology, Rajarajeshwari Medical college and Hospital, Bangalore from December 2014 to May 2016. Seventy-five cases of PCOS patients in the age group of 20-40 years, andseventy-five age-matched healthy women (control) with regular menstrual cycle were selected. The mean age of cases was 30.13 (SD=5.32) years and mean age of control group was 28.54 (SD=6.78) years. Further, in case group, 73.33% patients were Euthyroid, 6.66% were sub-clinical hyperthyroid, 14.66% were subclinical hypothyroid and 5.33% were clinical hypothyroid. The mean value of T3 for case group was 127.13 (SD = 51.23) and control group was 137.57 (SD = 59.49). Moreover, the mean value of T4 for case group was 8.17 (SD = 2.50) and control group was 9.45 (SD = 2.24). In case group, 12.7% Euthyroid patients, 54.5% subclinical hypothyroid and 75% clinical hypothyroid had anti-thyroid peroxidase+ (TPO+). On the other hand, in control group 7.7% Euthyroid and 66.9% subclinical hypothyroid were anti-TPO+. Euthyroid PCOS cases with anti TPO positive are at risk of developing hypothyroidism. Thus T3, T4 and TSH should be periodically evaluated in these subjects.