bluuebunny/crossref_metadata_2025_split huggingface dataset:
Implementasi Nilai-Nilai Pancasila Dalam Pembelajaran Ramah Anak Untuk Membentuk Karakter Anak Usia Dini 4-5 Tahun
Authors: Suadah  , Dewi Pusparini  , Musayyadah  
Published: August 2024

Nilai-nilai Pancasila merupakan dasar perilaku warga negara Indonesia. Oleh karena itu, pengimplementasian nilai-nilai Pancasila harus dilakukan sejak usia dini. Penelitian ini dilatar belakangi oleh permasalahan pengimplementasian niali-nilai Pancasila dalam pembelajaran untuk membentuk karakter anak usia dini 4-5 tahun di RA Sirojul Ulum desa Pangtonggal Kecamatan Proppo Kabupaten Pamekasan. Penelitian ini memiliki tujuan untuk mengetahui nilai-nilai Pancasila dalam pembentukan karakter anak apa saja yang dikembangkan di RA Sirojul Ulum, bagaimana pengimplementasian niali-nilai Pancasila dalam pembelajaran untuk membentuk karakter anak usia dini 4-5 tahun di RA Sirojul Ulum, serta kendala dalam pengimplementasian nilai-nilai Pancasila dalam pembelajaran untuk membentuk karakter anak usia dini dan upaya mengatasinya. Jenis penelitian menggunakan kualitatif deskriptif. Teknik pengumpulan data yang digunakan dalam penelitian ini yaitu observasi, wawancara, dan dokumentasi. Sumber data meliputi data primer dan data sekunder. Analisis data dilakukan dengan reduksi data, penyajian data, dan penarikan kesimpulan. Hasil penelitian menunjukkan bahwa sistem pembelajaran ramah anak di RA Sirojul Ulum terdapat beberapa nilai-nilai Pancasila yang diterapkan, namun dalam memberikan pembelajaran yang menganut nilai-nilai Pancasila untuk anak usia dini kurang maksimal, sehingga tidak semua nilai-nilai Pancasila diimplemetasikan. Penerapan nilai-nilai Pancasila juga kurang dipahami karena tidak adanya pembelajaran tentang nilai-nilai Pancasila yang berhubungan langsung dengan aktifitas sehari-hari.
FEITIÇOS COMUNEIROS NAS ORGANIZAÇÕES CULTURAIS CONTEMPORANEAS
Authors: Pereira Maria 
Published: August 2024

O artigo apresenta dados da pesquisa qualitativa realizada pelo Projeto Nanã entre 2022-2023 cujo foco esteve no levantamento de estratégias de sustentação econômica desenvolvidas por organizações culturais européias. Os resultados evidenciam a relevância de práticas ancoradas no 'fazer com' para a capacidade de autonomia e independência das organizações e apontam a contradições entre o fomento público/estatal e o atendimento ao público/comunidade. Argumenta-se que é urgente enfrentar certas armadilhas conceituais para expansão de políticas públicas-comunitárias.
Trends in Drug Overdose Deaths by Intent and Drug Categories, United States, 1999‒2022
Authors: Nguyen Anallely , Wang Jing , Holland Kristin M. , Ehlman Daniel C. , Welder Laura E. , Miller Kimberly D. , Stone Deborah M. 
Published: August 2024

Objectives. To examine trends in overdose deaths by intent and drug category to better understand the recent decrease in overdose suicides amid the overdose epidemic. Methods. We examined trends in rates of overdose deaths by intent (unintentional, suicide, or undetermined) across 9 drug categories from 1999 to 2022 using US National Vital Statistics System mortality data. Results. Unintentional overdoses involving synthetic opioids, polydrug toxicity involving synthetic opioids, psychostimulants, and cocaine increased exponentially with annual percentage changes ranging from 15.0% to 104.9% during 2010 to 2022. The death rates also increased for suicides involving these drugs, especially for psychostimulants (annual percentage change = 12.9% for 2010–2022; P < .001). However, these drugs accounted for relatively small percentages of overdose suicides. The leading drug categories among suicides were antidepressants, prescription opioids, and benzodiazepines, though these deaths have decreased or leveled off in recent years. Conclusions. Different drugs commonly involved in suicides and unintentional overdoses may contribute to their divergent trends. Public Health Implications. Amid the overdose epidemic, safe storage of medications remains a crucial strategy to prevent overdose suicides. The large increases in suicides involving psychostimulants warrant monitoring. ( Am J Public Health. 2024;114(10):1081–1085. https://doi.org/10.2105/AJPH.2024.307745 )
Single-Sided Capacitive Pressure Sensor with Tunable Performance Over a Wide Pressure Range
Authors: Andrews Joseph , Barton Vanessa , Tewani Hridyesh , Sun Xiangyu , Franck Christian , Prabhakar Pavana 
Published: August 2024

Abstract

Flexible pressure sensors have a wide range of applications including human body monitoring and robotic control. Recent work has focused on developing pressure sensors that excel at measuring pressure in the ultrasensitive range, often with parallel plate piezocapacitive sensors and a dielectric that relies on microstructures. However, these approaches have a few drawbacks including a limited range and high complexity leading to expensive and time-consuming manufacturing. To mitigate these problems, we demonstrate the fabrication of a low-cost, flexible, interdigitated electrode (IDE) pressure sensor with an overlaid layered elastomer composed of polydimethylsiloxane (PDMS) and Barium Titanate (BaTiO3). The elastomers are manipulated by modifying the mixing ratio, curing temperature, incorporation of BaTiO3, and compressed at two strain rates. Characterization of these elastomers and IDE geometry allows for insights into the behavior and tunability of the layered macrostructure and electrode design. As a result, the leading IDE geometry can be tuned to work in a lower range with a sensitivity of 77.8% per decade between 0 and 10 kPa and 4.5% per decade between 10 and 100 kPa or in a larger range with a sensitivity of 12.9% per decade between 0 and 100 kPa and 3.4% per decade between 100 and 500kPa.
Impact of Teacher-Student Rapport in Learning English at the Tertiary Level in Bangladeshi Context
Authors: Farzana Sadia Tul , Roy Sukanto 
Published: August 2024

Abstract

This study intends to explore the teacher-student rapport in the Bangladeshi tertiary-level (private universities) ESL (English as a second language) context following a mixed methodology scheme. For managing data of this research, a survey questionnaire has been provided to Bangladeshi private university students, and five one-to-one interview sessions have been arranged with three different private university teachers. In addition, two tertiary-level classrooms have been observed as a part of qualitative data collection. The result of this study suggests that both teachers and students have a positive attitude toward “Rapport,” and it helps language learning in a multidimensional way. Moreover, this study has addressed some challenges with their suggestive solutions in the end.
Quantitative and Health Risks Evaluations of Trace Metals in Soils and Cassava Tubers Cultivated in Farms Around Abandoned Ishiagu Mining Sites, Ebonyi State, Nigeria
Authors: Orji Obasi Uche , Agu Peter Chinedu , Okah Kingsley Nnaemeka , Ibiam Udu Ama , Elom Geraldine Ifeoma , Obasi Otuomasiri Divine , Ezeani Nkiruka Nwamaka , Orji Emmanuel , Nwiziogo Francisca Chidimma , Alum Esther Ugo , Aja Patrick Maduabuchi 
Published: August 2024

Abstract

Contamination of the environment with toxic metals can bring about possible pollution of cassava. Eating food crops contaminated with toxic metals is the main food chain pathway for human exposure. Some trace metals like Manganese, Copper, Zinc, Nickel, Lead, Selenium, Strontium, Niobium, Vanadium, and Iron in soil and their accumulation in cassava tubers collected from farms around abandoned mining sites at Ishiagu in Ebonyi State, Nigeria were analyzed with X-ray fluorescence spectrometer to evaluate the potential health risk to the dweller adults and children. Results show that there is an extensive build-up of toxic metals in farmland soils around the abandoned mining sites at Ishiagu, Ebonyi State. Levels of toxic metals in cassava grown in Farms around the mines were substantially higher (P < 0.05) than in cassava tubers grown in the reference soil, and exceeded the permissible limits set by the World Health Organization. In addition, this investigation reveals that both adults and children consuming cassavas grown in the area ingest appreciable quantities of the metals studied. The health risk indicator quantities of greater than 1 signal a strong presence of health risks connected with the eating of contaminated cassava.
Spatial Distribution Characteristics and Influencing Factors of Intangible Cultural Heritage in the Grand Canal Cultural Belt
Authors: jiao min , lu lu , li tianyu , lu baoyi , zhang yiyi 
Published: August 2024

Abstract

The spatial distribution characteristics and development process of national Intangible Cultural Heritage items (ICHs) in the Grand Canal Cultural Belt are closely related to the excavation and passage of the canal. Guided by the theory of the "man-land relationship areal system", the study used geographical space-time analysis to explore the spatial distribution characteristics of national ICHs in the broader and narrower Grand Canal Cultural Belt and measured the factors affecting the spatial distribution of ICHs in both quantitative and qualitative terms. The results show that: (1) The national ICHs in the Grand Canal Cultural Belt as a whole closely follow the developed central regions of Beijing, Tianjin, Hebei, Jiangsu, Zhejiang to form a cluster and take the high administrative level, economic development areas and historical and cultural cities along the canal as the core cluster areas in the provincial and municipal scales; (2) The Grand Canal Cultural Belt in a narrow sense is the main gathering area for all types of national ICHs, especially in the core cities along the canal, such as Beijing, Tianjin, Langfang, Suzhou, Wuxi, Hangzhou, Shaoxing, Ningbo. (3) the evolution trend of national ICHs in the Grand Canal Cultural Belt of different batches shows the cohesion trend to the canal always point area, and the core cities along the canal are still the main distribution areas of national ICHs in different batches, which further proves the close correlation between the canal and ICHs; (4) The results of Geodetector show that human factors have stronger explanatory power than natural factors, and the closer to the canal, the influence of human factors and natural factors on the spatial distribution of national ICHs are increased. Among human factors, the inheritors and financial support for cultural tourism are the most significant. The historical factors shape the depth of the connotation of ICHs in the historical space and time. The above study shows that a good natural and cultural ecological space of the canal is an important guarantee for the effective protection and adaptive use of national ICHs in the Grand Canal Cultural Belt.
Towards a Refined Climate Urbanism Typology: Comparing Local Policy Debates in German and American cities
Authors: Nagel Melanie , Jocoy Christine , House-Peters Lily 
Published: August 2024

Abstract

Cities are a key arena in confronting climate change. The concept of climate urbanism
describes this emerging policy approach for which climate change has made mitigation
and adaptation policies central to urban governance and life in cities. We contribute to
the existing canon of climate urbanism scholarship through an empirically driven
analysis of the discourse landscape in four cities facing pressure for climate action
planning and policy. In each city, we identify themes and evaluate how they fit into the
three modalities of a climate urbanism typology proposed by Castán Broto, Robin, and
While (2020): reactive, entrepreneurial, and transformative. Furthermore, our research
aims to identify which actors are driving these themes, which groups of actors
predominantly agree, and what fractures or disagreements exist in our four cities.
Informed by these empirical findings, we offer a more nuanced and expanded climate
urbanism typology.
Prediction of Low-temperature Performance of Asphalt based on Four-point Bending Notched Beam Test
Authors: Sun Zhiqi , Liu Pudong , Li Shaohua , Zhang Lei 
Published: August 2024

Abstract

The mechanism of thermal cracking in asphalt is closely linked to thermal cracks in asphalt pavements. Nevertheless, the majority of prior research on the low-temperature behavior of asphalt failed to comprehensively incorporate the thermal cracking mechanism. This work utilizes the fracture temperature as a criterion for assessing asphalt low-temperature cracking. It uses the four-point bending notched beam test (4P) to forecast the low-temperature behavior of asphalt. This prediction is made by deductive reasoning, taking into account the thermal cracking mechanism. The specific method was as follows: the viscoelastic properties and contraction strain of asphalt were determined through the main curve test and low-temperature contraction test, respectively. These results served as a basis for calculating thermal stress and pseudo cumulative strain energy. Additionally, the thermal stresses of asphalt were obtained by the Boltzmann superposition principle, and the pseudo cumulative strain energy density was calculated by using the line low-temperature contraction obtained from the low-temperature contraction test as the pseudo strain. 4P test was employed to determine the critical strength and critical energy of various asphalt cracking. These values were then utilized as a basis to deduce the fracture temperature of asphalt. The accuracy and reliability of this method for predicting the low-temperature performance of asphalt were confirmed by comparing the measured fracture temperatures of asphalt mixtures with the same gradation to the predicted values. A novel technique was presented for assessing the low-temperature performance of asphalt.
Emerging clean technologies: policy-driven cost reductions, implications and perspectives
Authors: Atouife Mohamed , Jenkins Jesse 
Published: August 2024

Abstract

Hydrogen production from water electrolysis, direct air capture (DAC), and synthetic kerosene derived from hydrogen and CO2 ('e-kerosene') are expected to play an important role in global decarbonization efforts. So far, the economics of these nascent technologies hamper their market diffusion. However, a wave of recent policy support in the United States, Europe, China, and elsewhere is anticipated to drive their commercial liftoff and bring their costs down. To this end, we evaluate the potential cost reductions driven by policy-induced scale-up of these emerging technologies through 2030 using an experience curves approach accounting for both local and global learning effects. We then analyze the consequences of projected cost declines on the competitiveness of these nascent technologies compared to conventional fossil alternatives, where applicable, and highlight some of the tradeoffs associated with their expansion. Our findings indicate that enacted policies could lead to substantial capital cost reductions for electrolyzers. Nevertheless, electrolytic hydrogen production at \$1-2/kg would still require some form of policy support. Given expected costs and experience curves, it is unlikely that liquid solvent DAC (L-DAC) scale-up will bring removal costs to stated targets of $100/tCO2, though a $200/tCO2 may eventually be within reach. We also underscore the importance of tackling methane leakage for natural gas-powered L-DAC: unmitigated leaks amplify net removal costs, exacerbate the investment requirements to reach targeted costs, and cast doubt on the technology's role in the clean energy transition. Lastly, despite reductions in electrolysis and L-DAC costs, e-kerosene remains considerably more expensive than fossil jet fuel. The economics of e-kerosene and the resources required for production raise questions about the fuel's ultimate viability as a decarbonization tool for aviation.
Integration of QTL and Transcriptome Studies Reveals Candidate Genes for Water Stress Response in St. Augustinegrass
Authors: Rockstad Greta , Yu Xingwang , Gesteira Gabriel de Siqueira , Gaire Susmita , Dickey Allison , Gouveia Beatriz T. , Schoonmaker Ashley N. , Hulse-Kemp Amanda M. , Milla-Lewis Susana R. 
Published: August 2024

Abstract

Background
Drought resistance is an increasingly important trait for many plants—including St. Augustinegrass, a major warm-season turfgrass—as more municipalities impose restrictions on frequency and amount of irrigation. Breeding efforts have focused on breeding for drought resistance, and several drought-related QTL have been identified for St. Augustinegrass in our previous studies. However, the molecular basis of this trait is still less understood, which has been a significant roadblock for genetic improvement of the species.
Results
This study sought to validate those QTL regions in an independent biparental population developed from two sibling lines, XSA10098 and XSA10127. The drought evaluation in two greenhouse trials showed significant genotype variation for drought stress traits including leaf wilting, percent green cover, relative water content, percent recovery, and the area under the leaf wilting-, percent green cover-, and percent recovery- curves. A linkage map was constructed from a total of 12,269 SNPs, representing the densest St. Augustinegrass linkage map to date. Twenty-four QTL were identified from a multiple QTL mapping approach, and overlapping regions from this study and previous St. Augustinegrass drought resistance studies were found on linkage groups 3, 4, 6, and 9. At the transcriptome level, 1965 and 1005 differentially expressed genes were identified in the drought sensitive and tolerant genotypes, respectively. Gene Ontology and KEGG analysis found different mechanisms adopted by the two genotypes in response to drought stress. Integrating QTL and transcriptomics analyses revealed several candidate genes which are involved in processes including cell wall organization, photorespiration, zinc ion transport, regulation of reactive oxygen species, channel activity, and regulation in response to abiotic stress.
Conclusions
These results represent a step toward understanding the genetic control of water stress response in St. Augustinegrass and provide a theoretical basis for genetic improvement of drought resistance in this species.
Synthesis of 6-dialkylaminopyrimidine carboxamide analogues and their anti-tubercular properties
Authors: Tshinavhe Ronewa , Peton Nashied , Simelane Sandile B. , Moshapo Paseka 
Published: August 2024

Abstract

Tuberculosis (TB) continues to be a threat to global health stability. Pyrimidine carboxamides have demonstrated potent anti-tubercular properties against clinical Mycobacterium tuberculosis, the causative agent of TB. Herein, we report a follow-up study on the synthesis of pyrimidine carboxamide molecular analogues and their anti-TB evaluation. In total, a library consisting of 37 new compounds is reported. Seven compounds (7b, 7d, 7m, 7p, 7q, 7aa, and 7ah) demonstrated excellent in vitro activities with MIC90 values below 1.00 µM. Apart from compound 7ah, compounds with improved aqueous solubility properties had lower anti-TB potency. Preliminary mode of action studies using bioluminescence assays indicate that the active compounds do not affect the integrity of mycobacterial DNA or the cell wall. The active compounds were also found to be bactericidal against replicating H37Rv Mtb strain.
Risk of Hospital INpatient Opioid Overdose (RHINOO): A review of factors impacting naloxone administration in patients receiving opioids
Authors: Alban Heather , Ireifej Natasha , D’Alessandro John , Jordan Garrett , Lee Ryan , Patricia Nicholas , Stolzfus Jillian , Niyibizi Auguste 
Published: August 2024

Abstract

Purpose:
Opioid medications remain a common treatment for acute pain in hospitalized patients. This study aims to identify factors contributing to opioid overdose in the inpatient population, addressing the gap in data on which patients are at higher risk for opioid-related adverse events in the hospital setting.
Methods:
A retrospective chart review of inpatients receiving at least one opioid medication was performed at a large academic medical center from January 1, 2022, through December 31, 2022. Patients who received naloxone were designated as the study group, while those who received opioids without naloxone served as the control group. Suspected risk factors were included in a multivariable direct logistic regression model to identify patients at higher risk for opioid-related adverse events.
Results:
The review included 11,050 admitted patients who received an inpatient opioid, of whom 130 received naloxone. Analysis revealed that patients with creatinine clearance (CrCl) < 60 mL/min, co-administered benzodiazepine, body mass index (BMI) > 30 kg/m², underlying pulmonary disease, obstructive sleep apnea, chronic opioid use, and/or substance use disorder were at higher risk for requiring naloxone. These factors significantly influenced the likelihood and magnitude of in-hospital opioid overdose.
Conclusion:
These validated risk factors should be considered when administering opioid analgesics in the inpatient setting. Consideration should be given to reducing the dose and/or frequency of opioids in addition to the use of alternative analgesic modalities for patients with these risk factors to mitigate the risk of opioid-related adverse events. Incorporating these considerations into clinical practice can enhance patient safety and outcomes.
Evaluation of interactions between anxiolytic drugs and human serum albumin as a ternary system: In vitro and in silico approaches
Authors: Jalali Elaheh , Sargolzaei Javad , Rajabi Parisa 
Published: August 2024

Abstract

In recent years, buspirone has been co-administered with sertraline to resolve sexual disorders caused by sertraline. Therefore, the present study was conducted to investigate the interaction effect of two antidepressants and anxiolytic drugs, sertraline and buspirone, on human serum albumin (HSA) using spectroscopic and molecular docking techniques. Fluorescence emission spectroscopy and molecular docking were used to calculate the binding affinity and determine the best binding sites for these two drugs. Additionally, UV-visible and circular dichroism spectroscopy were performed to investigate the effect of these drugs on the conformational changes of HSA. The results showed that both drugs have a strong ability to quench the fluorescence of HSA through a static mechanism, and cause structural changes in HSA. It was also found that binding of sertraline and buspirone to HSA is spontaneous and hydrophobic interactions, van der Waals forces and hydrogen bonds play a significant role in these interactions in the ternary system. In addition, molecular docking data showed that both drugs bind with high affinity to the Trp residue in subdomain IIA. This study demonstrates that the presence of the second drug (buspirone/sertraline) affects the interaction and binding affinity of the first drug (sertraline/buspirone) to human serum albumin.