bluuebunny/crossref_metadata_2025_split huggingface dataset:
Study protocol for the Multimodal Approach to Preventing Suicide in Schools (MAPSS) project: A regionally based feasibility trial of an integrated response to suicide risk among UK secondary school pupils
Authors: Ashworth Emma , McCarthy Molly , Wynne Sio , Robinson Jo , McKay Samuel , Lane Steven , Richardson Gerry , Boardman Neil , Henderson Kate , Crosbie Vivienne , Humphrey Neil , York Sian , Michail Maria , Hart Damian , Clacy David , Jalota Mani , Saini Pooja 
Published: July 2024

Background
Suicide is the leading cause of death of children and young people under 35 in the UK, and suicide rates are rising in this age group. Schools are considered an appropriate and logical setting for youth suicide prevention activities, with universal, selective, and indicated approaches all demonstrating efficacy. Given that international best practice recommends suicide prevention programmes combine these approaches, and that to date this has not been done in school settings in the UK, this study aims to evaluate the feasibility of delivering a suicide prevention programme incorporating universal, selective, and indicated components in UK schools.

Methods
This study is a feasibility cluster-randomised controlled trial (RCT) of an adapted version of the Multimodal Approach to Preventing Suicide in Schools (MAPSS) programme. The programme, initially developed in Australia, involves delivering universal psychoeducation to all pupils, screening them for suicide risk, and delivering Internet-based Cognitive Behavioural Therapy (Reframe IT-UK) to those students identified as being at high-risk for suicide. The programme will be trialled in six secondary schools in Northwest England and will target Year 10 students (14- and 15-year-olds). The primary aims are to assess: 1) the acceptability and safety of delivering MAPSS in a school setting in the UK; 2) the social validity of the MAPSS programme; and 3) the feasibility of delivering a large-scale, appropriately powered, cluster-RCT and economic evaluation of this intervention in the future. Secondary aims are to assess changes over time in mental health and wellbeing outcomes.

Discussion
This study is the first to evaluate a suicide prevention programme comprising universal, selective, and indicated components in UK schools. If the programme is found to be feasible, it could be more widely tested in schools and may ultimately lead to reduced rates of suicide and suicidal behaviour in young people.
Effects of using wearable devices to monitoring physical activity in pulmonary rehabilitation programs for chronic respiratory diseases: A systematic review protocol
Authors: Oliveira Thaianne Rangel Agra , Fernandes Ana Tereza do Nascimento Sales Figueiredo , Santino Thayla Amorim , Menescal Fernanda Elizabeth Pereira da Silva , Nogueira Patrícia Angélica de Miranda Silva 
Published: July 2024

Introduction
Pulmonary rehabilitation (PR) is an intervention aimed at the comprehensive care of individuals with chronic respiratory diseases. Patients with chronic obstructive pulmonary disease (COPD) and asthma present low levels of physical fitness because they avoid physical exercises due to the fear of triggering recurrent symptoms. Wearable devices have been integrated into behavioral modification interventions for physical activity in PR protocols. Therefore, this review aims to identify how wearable devices are being utilized for monitoring chronic respiratory diseases in pulmonary rehabilitation programs.

Methods and analysis
Searches will be conducted on Medline, Cochrane Central Register of Controlled Trials, Embase (CENTRAL), CINAHL and PEDro electronic databases, as well as a search in the grey literature. We will include baseline data from randomized clinical trials reporting the use of wearable devices for monitoring physical activity in protocols for pulmonary rehabilitation programs for chronic respiratory diseases. Studies that discuss only the development of algorithms or applications for the assessment of diseases or unavailable full texts will be excluded. The main reviewer will conduct the initial search and exclusion of duplicates, while two independent reviewers will select studies, extract data, and assess the methodological quality using the PEDro tool.

PROSPERO registration number
CRD42024504137.
Inpatient Gastroenterology Consults Have Little Utility Before Transesophageal Echocardiograms in a Prospective Cohort Study
Authors: Mizrahi Joseph , Marhaba Jade , Paradkar Anika , Klyachman Leslie , Menashe Eyal , Jamorabo Daniel S. 
Published: July 2024

INTRODUCTION:
Despite the well-documented safety of transesophageal echocardiograms (TEEs), inpatient gastroenterology (GI) services are called to clear patients for the procedure when they have GI symptoms or comorbidities ranging from mild to clinically significant. We aimed to assess the clinical utility of such consults in preventing TEE complications.

METHODS:
We performed a prospective cohort study of all inpatients at our institution who had a TEE ordered from 7/1/2021 through 7/1/2022. Patients' demographic information, indications for TEE, complications from TEE, 30-day readmission rates, GI team recommendations, and results of any GI-related interventions were collected and analyzed.

RESULTS:
There were 732 patients who had a TEE ordered during our study period, of whom 641 (87.51%) underwent the procedure. Of the 91 (12.49%) who did not have a TEE, none were canceled due to a GI-related concern. There were 23 of 641 patients (3.59%) with complications from the TEE, none of which were GI-related. The GI team was consulted on 36 patients (4.96% of TEEs ordered) and cleared 22 of 36 (61.11%) with no further testing while the remaining 14 of 36 patients (38.89%) underwent workups that were largely normal. Patients who had a GI consult before their TEE had a significantly longer time between their TEE being ordered and the TEE being performed compared with those who did not have a GI consult before their TEE (4.50 days vs 0.77 days, P < 0.01).

DISCUSSION:
Inpatient GI team workups to clear patients for a TEE found no contraindications to TEEs, did not change patient care plans, and led to increased hospital costs and lengths of stay.
Estimación del confort térmico en espacios exteriores: evaluación del periodo frío en Ensenada, Baja California
Authors: Martínez-Bermúdez Elizabeth , Rincón-Martínez Julio César 
Published: July 2024

Los estudios del confort térmico en espacios exteriores son fundamentales para favorecer la habitabilidad de los espacios abiertos y mejorar las condiciones de vida de las personas; sin embargo, es necesario que sean producto de las características locales y de las personas del sitio donde se desarrollan los estudios. El objetivo de este trabajo es evaluar la sensación térmica humana durante el periodo frío, con el fin de estimar los rangos de confort térmico para espacios exteriores que permitan ofrecer indicadores de diseño. Para ello, se recabaron observaciones en diversos tipos de espacios abiertos de la ciudad de Ensenada, única en México con clima mediterráneo, con inviernos fríos y húmedos. La evaluación se realizó mediante el enfoque adaptativo y se procesó con el método de Medias por Intervalos de Sensación Térmica (MIST). Se realizó un análisis correlacional respecto a la sensación térmica con las variables climáticas de temperatura del aire, humedad relativa y velocidad de viento. El rango de confort térmico fue de 12,6 ºC a 23,8 ºC, valores por debajo de los rangos anuales estimados para regiones climáticas mediterráneas (21,1 ºC-29,2 ºC y 20 ºC-25 ºC) en el mismo periodo de estudio.
Circulating plasma fibronectin affects tissue insulin sensitivity, adipocyte differentiation, and transcriptional landscape of adipose tissue in mice
Authors: Mahmoodi Mahdokht , Mirzarazi Dahagi Elahe , Nabavi Mir‐Hamed , Penalva Ylauna C. M. , Gosaine Amrita , Murshed Monzur , Couldwell Sandrine , Munter Lisa M. , Kaartinen Mari T. 
Published: July 2024

AbstractPlasma fibronectin (pFN) is a hepatocyte‐derived circulating extracellular matrix protein that affects cell morphology, adipogenesis, and insulin signaling of adipocytes in vitro. In this study, we show pFN accrual to adipose tissue and its contribution to tissue homeostasis in mice. Hepatocyte‐specific conditional Fn1 knockout mice (Fn1−/−ALB) show a decrease in adipose tissue FN levels and enhanced insulin sensitivity of subcutaneous (inguinal), visceral (epididymal) adipose tissue on a normal diet. Diet‐induced obesity model of the Fn1−/−ALB mouse showed normal weight gain and whole‐body fat mass, and normal adipose tissue depot volumes and unaltered circulating leptin and adiponectin levels. However, Fn1−/−ALB adipose depots showed significant alterations in adipocyte size and gene expression profiles. The inguinal adipose tissue on a normal diet, which had alterations in fatty acid metabolism and thermogenesis suggesting browning. The presence of increased beige adipocyte markers Ucp1 and Prdm16 supported this. In the inguinal fat, the obesogenic diet resulted in downregulation of the browning markers and changes in gene expression reflecting development, morphogenesis, and mesenchymal stem cell maintenance. Epididymal adipose tissue showed alterations in developmental and stem cell gene expression on both diets. The data suggests a role for pFN in adipose tissue insulin sensitivity and cell profiles.
LncRNA MIR17HG alleviates heart failure via targeting MIR17HG/miR-153-3p/SIRT1 axis in in vitro model
Authors: Sun Shuai , Weng Jianxin , Chen Yun , Zheng Tingting , Li Yan , Zhu Jianfei , Chen Yanjun 
Published: July 2024

Abstract
Heart failure (HF) is a syndrome of symptoms and signs caused by cardiac insufficiency and have become a serious global health problem. The aim of this study is to clarify the role and mechanism failure of MIR17HG. We established the in vitro HF model by using H2O2-treated AC-16 and HCM cells, and the reactive oxygen species (ROS) level and natriuretic peptide precursor B (NPPB) expression were also detected. The RNA expression of MIR17HG, miR-153-3p, SIRT1, and NPPB were detected by quantitative reverse transcription PCR while the SIRT1 and NPPB expression were detected by western blot. The binding relationship among MIR17HG, miR-153-3p, and SIRT1 were assessed by dual-luciferase reporter assay and RNA binding protein immunoprecipitation assay. Then, MIR17HG and SIRT1 were overexpressed by lentivirus transfection, and the influence of MIR17HG and SIRT1 on H2O2-induced apoptosis mediated by p53 were evaluated. The results show that MIR17HG and SIRT1 were significantly downregulated, while miR-153-3p was significantly upregulated in HF model. Overexpression of MIR17HG reduced miR-153-3p and alleviated HF, while knockdown of SIRT1 weakened the effects of MIR17HG, suggesting that SIRT1 was the direct target of MIR17HG/miR-153-3p axis. MIR17HG is significantly downregulated in HF model. Our research shows that MIR17HG protects cardiomyocytes from ROS-induced damage via the MIR17HG/miR-153-3p/SIRT1 axis, suggesting that MIR17HG and SIRT1 are potential therapeutic targets in HF.
Pathological and physiological roles of ADP-ribosylation: established functions and new insights
Authors: Feijs-Žaja Karla L.H. , Ikenga Nonso J. , Žaja Roko 
Published: July 2024

Abstract
The posttranslational modification of proteins with poly(ADP-ribose) was discovered in the sixties. Since then, we have learned that the enzymes involved, the so-called poly(ADP-ribosyl)polymerases (PARPs), are transferases which use cofactor NAD+ to transfer ADP-ribose to their targets. Few PARPs are able to create poly(ADP-ribose), whereas the majority transfers a single ADP-ribose. In the last decade, hydrolases were discovered which reverse mono(ADP-ribosyl)ation, detection methods were developed and new substrates were defined, including nucleic acids. Despite the continued effort, relatively little is still known about the biological function of most PARPs. In this review, we summarise key functions of ADP-ribosylation and introduce emerging insights.
Methodology Used to Update the Gasoline Volatility Schedule for U.S. Seasonal and Geographic Classes
Authors:   ASTM International
Published: July 2024

Description
A team of stakeholders from ASTM Subcommittee D02.A on Gasoline and Oxygenated Fuels developed a revision to the seasonal and geographic volatility schedule for gasoline in the United States. The members of the team represented all classifications of the subcommittee: fossil and renewable fuels, automobile manufacturers, government regulators, logistics (shipping), and transport sectors. The team worked for two years with more than 1,300 hours of personal effort to revise this important schedule (see ASTM D4814, Standard Specification for Automotive Spark-Ignition Engine Fuel, Table 4). A volatility table has been included in ASTM D4814, and its predecessor ASTM D439-85a, Standard Specification for Automotive Gasoline (Withdrawn 1990), since the inception of these standard specifications. The original table was developed using weather data and decades of vehicle testing programs. This stakeholder group reviewed all of the historical and present data to develop volatility limits to provide a standard that should deliver acceptable driveability to the consumer.
APPROACHES TO DETERMINING THE GEOMETRIC PARAMETERS OF LIQUID DROPLETS USING DIGITAL IMAGE ANALYSIS
Authors: НАЗАРОВ Н.А. , БАРАНОВ И.Н. , МИСЬКИВ Н.Б. , СТАРИНСКАЯ Е.М. 
Published: July 2024

В настоящее время актуальными задачами являются исследования в области спрейного охлаждения, взаимодействия капель со сложноструктурированными поверхностями, испарения капель различных жидкостей с твёрдой стенки и т. п. При проведении такого рода экспериментов, требующих записи большого количества видеоданных, ключевую роль играют методы автоматической обработки цифровых изображений. Предложены методы распознавания объекта на цифровом изображении для получения количественных характеристик испаряющихся капель в условиях недостаточного освещения. Разработаны новые алгоритмы выделения и замыкания границ объектов в условиях недостаточной видимости, с помощью которых выполнены измерения геометрических параметров испаряющихся капель. Проведено сравнение с данными, полученными методом ручной обработки изображений, продемонстрированы условия применимости предложенных алгоритмов.
Currently, ongoing tasks involve research in the field of spray cooling, droplet interaction with complex surfaces, and droplet evaporation from solid walls. Automated digital image processing methods are utilized to conduct these experiments, particularly when recording large amounts of video data. This paper presents methods for recognizing objects in digital images to obtain quantitative characteristics of evaporating droplets in low-light conditions. New algorithms have been developed to identify and close object boundaries under conditions of limited visibility, enabling measurement of the geometric parameters of evaporating droplets. A comparison is made with data obtained using the manual image processing method, and the conditions for the applicability of the proposed algorithms are demonstrated.
OBTAINING COMPOSITE MATERIALS OF THE SYSTEM Al – METALLIC GLASS Fe66Cr10Nb5B19, POSSESSING ANISOTROPY OF MECHANICAL PROPERTIES
Authors: КВАШНИН В.И. , НОВОСЕЛОВ А.Н. , ЛЕГАН М.А. , ЕСИКОВ М.А. , ГАВРИЛОВ А.И. , УХИНА А.В. 
Published: July 2024

Описывается получение композиционных материалов с алюминиевой матрицей, содержащих частицы металлического стекла состава Fe66Cr10Nb5B19, путем последовательного применения механической активации исходных порошков в планетарной мельнице и электроискрового спекания. В ходе спекания при 540 °C происходит полное или частичное превращение частиц металлического стекла в интерметаллидное соединение Fe4Al13. Композиционные материалы, спеченные из смеси Al + 20 (об.) % Fe66Cr10Nb5B19, характеризуются анизотропией механических свойств: предел текучести при сжатии, микротвердость и деформация при разрушении в направлении прессования при спекании составляют 550 МПа, 200 HV и 14.2 % соответственно, в то время как в направлении, перпендикулярном направлению прессования, данные характеристики составляют 740 МПа, 250 HV и 2.2 %.
The paper describes the production of aluminum matrix composite materials containing metallic glass particles of the composition Fe66Cr10Nb5B19 by successively applying mechanical activation of the initial powders in a planetary mill and spark sintering. During sintering at 540 °C, the metallic glass particles are completely or partially converted into the intermetallic compound Fe4Al13. Composite materials sintered from a mixture of Al + 20 (vol.) % Fe66Cr10Nb5B19 are characterized by anisotropy of mechanical properties: the yield strength in compression, microhardness and deformation at failure in the pressing direction during sintering are 550 MPa, 200 HV and 14.2%, respectively, while in the direction perpendicular to the pressing direction, these characteristics are 740 MPa, 250 HV and 2.2%
Early Childhood Care Coordination Through 211: A Randomized Clinical Trial
Authors: Nelson Bergen B. , Dudovitz Rebecca N. , Thompson Lindsey R. , Vangala Sitaram , Zevallos-Roberts Emilia , Gulsrud Amanda , Porras-Javier Lorena , Romley John A. , Herrera Patricia , Aceves Irene , Chung Paul J. 
Published: July 2024

BACKGROUND AND OBJECTIVES
Early intervention services can improve outcomes for children with developmental delays. Health care providers, however, often struggle to ensure timely referrals and services. We tested the effectiveness of telephone-based early childhood developmental care coordination through 211 LA, a health and human services call center serving Los Angeles County, in increasing referral and enrollment in services.

METHODS
In partnership with 4 clinic systems, we recruited and randomly assigned children aged 12 to 42 months with upcoming well-child visits and without a known developmental delay, to intervention versus usual care. All children received developmental screening and usual clinic care. Intervention children also received telephone connection to a 211 LA early childhood care coordinator who made referrals and conducted follow-up. Primary outcomes at a 6-month follow-up included parent-reported referral and enrollment in developmental services. Secondary outcomes included referral and enrollment in early care and education (ECE). Logistic regression models were used to estimate the odds of outcomes, adjusted for key covariates.

RESULTS
Of 565 families (282 intervention, 283 control), 512 (90.6%) provided follow-up data. Among all participants, more intervention than control children were referred to (25% vs 16%, adjusted odds ratio [AOR] 2.25, P = .003) and enrolled in (15% vs 9%, AOR 2.35, P = .008) ≥1 service, and more intervention than control children were referred to (58% vs 15%, AOR 9.06, P &lt; .001) and enrolled in (26% vs 10%, AOR 3.75, P &lt; .001) ECE.

CONCLUSIONS
Telephone-based care coordination through 211 LA is effective in connecting young children to developmental services and ECE, offering a potentially scalable solution for gaps and disparities.
Two-year training program-induced cardiorespiratory developments in adolescent female handball players: The importance of playing position
Authors: Béres B. , Györe I. , Pálinkás G. , Szabó T. , Drenjančević I. , Koller A. 
Published: July 2024

AbstractAs there are few data available, we aimed to assess the development of the cardiorespiratory system of young female athletes following a two-year training program (2y-TP) and explore the game position-specific changes.MethodsBefore and after the 2y-TP body compositions of young elite female handball players (age: 14.2 ± 0.5 years, n = 33) were investigated by dual-energy x-ray absorptiometry (DEXA). The morphological changes of the heart were assessed by echocardiography, and cardiorespiratory values were investigated by spiroergometry.ResultsCompared to initial values, after the 2y-TP, significant increases were found in body mass (by 8.8%), skeletal muscle mass (by 7.7%), and body fat (by 11.3%), power (by 7.8%), VO2 (by 10.6%), VCO2 (by 8.3%), oxygen pulse (by 13.8%), ventilation (by 13.4%), tidal volume (by 13.7%), left ventricular mass (by 24.8%), stroke volume (by 21.2%), and stroke volume normalized to the body surface (by 16.4%). Heart rate decreased (by 2.9%), whereas respiratory frequency, load time, relative power, and relative VO2 did not change. During the test, the goalkeepers run for a shorter time than the wing players at the initial time point and after the 2y-TP. Also, the maximum heart rate did not change in goalkeepers, whereas it decreased in wing players after the 2y-TP. Thus, the goalkeepers had a higher initial VO2 value at VO2peak than wing players, and differences, which were maintained after the 2y-TP, as well. In contrast, in goalkeepers, the relative VO2 at the VO2peak was initially lower than in wing players, which remained lower after the 2y-TP, as well.ConclusionsIn adolescent female handball players, the 2y-TP significantly improved skeletal muscle mass, which corresponded to significant improvements of cardiorespiratory function, which were more accentuated in wing players, compared to goalkeepers, likely due to the different loads during trainings and matches.
The predominance of sustainability perspectives in sports – A bibliometric analysis
Authors: Boros Anita , Tőzsér Dávid , Géczi Gábor 
Published: July 2024

AbstractIn the last decade, sustainability has become a keyword that must be addressed in any environment, society, or economy segment. Therefore, the relevance of sustainable operation and behaviour in complexly interrelated fields like sports is particularly actual. This study was designed to evaluate the demonstration of sports sustainability in the relevant literature by bibliometric analysis. The yearly number of publications, core topics, Sustainable Development Goal (SDG)-connection, author and affiliation patterns, most relevant journals, and terms and keywords were studied to thoroughly overview the trends. It was found that the number of papers is increasing, however, with a slight setback in the last few years. The main topics relate to several environmental, economic (social), governmental (ESG) segments, but the listed publications need more SDG connections. A high proportion of fundamental papers from the research area are from authors affiliated with a narrow group of countries, and one journal published relatively far the most articles. The most relevant keywords are sustainability, physical activity, and sport, while the primary topic hot spots can be classified into four clusters. In conclusion, more in-depth publications are required to reveal the underrepresented field of sports sustainability in the literature, which should simultaneously incorporate the environmental, social, and economic aspects. This would foster better understanding, public awareness, and the spread of best practices in theory and practice, which could be implemented as an attitude-formation tool.