bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of Cervical Lengths Using Transabdominal and Transvaginal Sonography in Midpregnancy
Authors: Roh Hyun-Jin , Ji Yong Il , Jung Chul Hoi , Jeon Gyun Ho , Chun Sungwook , Cho Hyun Jin 
Published: September 2013

ObjectivesCervical length assessment is helpful to predict and prevent preterm birth. However, transvaginal sonography is not easy to perform. The aim of this study was to investigate the relationship and discrepancies between cervical lengths measured by transabdominal and transvaginal sonography in midpregnancy.MethodsTransabdominal and transvaginal cervical lengths were measured in 255 pregnant women between 20 and 29 gestational weeks. The discrepancies in cervical lengths between the two methods were analyzed for the following maternal and fetal conditions: (1) vertex versus breech fetal presentation, (2) whether the fetal presenting part overlay the cervical internal os, (3) whether both the internal os and external os were visible or only the internal os was clearly visible, (4) maternal bladder filling status, (5) maternal age, (6) parity, and (7) gestational age.ResultsThe mean cervical lengths were not significantly different (mean ± SD, 3.88 ± 0.73 cm on transabdominal sonography and 3.93 ± 0.72 cm on transvaginal sonography; P = .129; Pearson r = 0.75). The 5th‐percentile transabdominal cervical length was 26.0 mm, and the transvaginal length was 27.8 mm. There were significant discrepancies between the two methods in the cases in which a fetal presenting part overlay the internal os, in the cases in which the external os was not clearly visible, and in primiparous women. Transabdominal cervical measurements were consistently shorter than transvaginal measurements in the cases with discrepancies.ConclusionsTransabdominal cervical length measurements are correlated with transvaginal measurements overall, and the transabdominal length is consistently shorter than the transvaginal length in cases with discrepancies. Transabdominal sonography could be used as a cervical length screening tool.
Reference Ranges for Fetal Septum Primum Excursion From 14 to 40 Weeks' Gestation
Authors: Mekjarasnapha Manasicha , Traisrisilp Kuntharee , Luewan Suchaya , Srisupundit Kasemsri , Tongprasert Fuanglada , Tongsong Theera 
Published: September 2013

ObjectivesThe purpose of this study was to establish reference ranges for septum primum excursion and the septum primum excursion index.MethodsNormal singleton pregnancies with certain dates from 14 to 40 weeks' gestation were enrolled to acquire spatiotemporal image correlation volume data sets. The stored data sets were subsequently displayed offline to measure septum primum excursion and the left atrium diameter. The measured values were regressed to identify the best‐fitted model as a function of gestational age and biparietal diameter.ResultsA total of 624 volumes were successfully measured, and normal reference ranges for predicting means and standard deviations of septum primum excursion and the septum primum excursion index were established based on best‐fitted equations. The septum primum excursion index was relatively constant throughout pregnancy (mean ± SD, 0.474 ± 0.082), whereas septum primum excursion increased with gestational age and biparietal diameter as follows: (1) septum primum excursion = −6.30 + 0.667 × gestational age − 0.009 × gestational age2; SD of septum primum excursion = 0.219 + 0.02 × gestational age; and (2) septum primum excursion = −3.342 + 1.933 × biparietal diameter − 0.102 × biparietal diameter2; SD of septum primum excursion = 0.330 + 0.065 × biparietal diameter. Percentile charts for predicting septum primum excursion and equations for Z score calculation were also provided.ConclusionsNormal reference ranges for fetal septum primum excursion and the septum primum excursion index have been provided. These normative data may be useful tools for assessment of hemodynamics through the foramen ovale or left ventricular diastolic function.
Ultrasound Backscatter Microscopy for Imaging of Oral Carcinoma
Authors: Lam Matthew , Chaudhari Abhijit J. , Sun Yang , Zhou Feifei , Dobbie Allison , Gandour-Edwards Regina F. , Tinling Steve P. , Farwell D. Gregory , Monsky Wayne L. , Shung K. Kirk , Marcu Laura 
Published: September 2013

ObjectivesUltrasound backscatter microscopy (UBM), or ultrasound biomicroscopy, is a noninvasive, label‐free, and ionizing radiation–free technique allowing high‐resolution 3‐dimensional structural imaging. The goal of this study was to evaluate UBM for resolving anatomic features associated with squamous cell carcinoma of the oral cavity.MethodsThe study was conducted in a hamster buccal pouch model. A carcinogen was topically applied to cheeks of 14 golden Syrian hamsters. Six additional hamsters served as healthy controls. A high‐frequency (41 MHz, 6‐mm focal depth, lateral and axial resolutions of 65 and 37 μm, respectively) UBM system was used for scanning the oral cavity after 14 weeks of carcinogen application. Histologic analyses were conducted on scanned regions.ResultsThe histologic structure of buccal tissue and microvasculature networks could be visualized from the UBM images. Epithelial and mucosal hypertrophy and neoplastic changes were identified in animals subjected to the carcinogen. In animals with invasive squamous cell carcinoma, lesion development and destruction of the structural integrity of tissue layers were noted.ConclusionsIn this pilot study, UBM generated sufficient contrast for morphologic features associated with oral carcinoma compared to healthy tissue. This modality may present a practical technique for detection of oral neoplasms that is potentially translatable to humans.
Diagnostic Efficacy of Contrast‐Enhanced Sonography by Combined Qualitative and Quantitative Analysis in Breast Lesions
Authors: Wang Lin , Du Jing , Li Feng-Hua , Fang Hua , Hua Jia , Wan Cai-Feng 
Published: September 2013

ObjectivesThe purpose of this study was to evaluate the diagnostic efficacy of contrast‐enhanced sonography for differentiation of breast lesions by combined qualitative and quantitative analyses in comparison to magnetic resonance imaging (MRI).MethodsFifty‐six patients with American College of Radiology Breast Imaging Reporting and Data System category 3 to 5 breast lesions on conventional sonography were evaluated by contrast‐enhanced sonography and MRI. A comparative analysis of diagnostic results between contrast‐enhanced sonography and MRI was conducted in light of the pathologic findings.ResultsPathologic analysis showed 26 benign and 30 malignant lesions. The predominant enhancement patterns of the benign lesions on contrast‐enhanced sonography were homogeneous, centrifugal, and isoenhancement or hypoenhancement, whereas the patterns of the malignant lesions were mainly heterogeneous, centripetal, and hyperenhancement. The detection rates for perfusion defects and peripheral radial vessels in the malignant group were much higher than those in the benign group (P < .05). As to quantitative analysis, statistically significant differences were found in peak and time‐to‐peak values between the groups (P < .05). With pathologic findings as the reference standard, the sensitivity, specificity, and accuracy of contrast‐enhanced sonography and MRI were 90.0%, 92.3%, 91.1% and 96.7%, 88.5%, and 92.9%, respectively. The two methods had a concordant rate of 87.5% (49 of 56), and the concordance test gave a value of κ = 0.75, indicating that there was high concordance in breast lesion assessment between the two diagnostic modalities.ConclusionsContrast‐enhanced sonography provided typical enhancement patterns and valuable quantitative parameters, which showed good agreement with MRI in diagnostic efficacy and may potentially improve characterization of breast lesions.
Rapid Response Survey Gauges Sandy's Impact on Seafloor
Authors: Goff John A. , Austin James A. , Flood Roger D. , Christensen Beth , Browne Cassandra M. , Saustrup Steffen 
Published: September 2013

In January 2013, approximately 2 months after Hurricane Sandy made landfall in the Mid‐Atlantic Bight, scientists from the University of Texas Institute for Geophysics (UTIG), part of the Jackson School of Geosciences (JSG), partnered with local colleagues at Adelphi and Stony Brook universities and the U.S. Geological Survey (USGS) to conduct marine surveys both offshore and within inshore bays of Long Island, N. Y. (Figure 1a). The primary goal was to assess the storm's impact on the seabed.
Measuring brain perfusion with intravoxel incoherent motion (IVIM): Initial clinical experience
Authors: Federau Christian , O'Brien Kieran , Meuli Reto , Hagmann Patric , Maeder Philippe 
Published: September 2013

PurposeTo evaluate the feasibility of intravoxel incoherent motion (IVIM) perfusion measurements in the brain with currently available imaging systems.Materials and MethodsWe acquired high in‐plane resolution (1.2 × 1.2 mm2) diffusion‐weighted images with 16 different values of b ranging from 0 to 900 s/mm2, in three orthogonal directions, on 3T systems with a 32‐multichannel receiver head coil. IVIM perfusion maps were extracted by fitting a double exponential model of signal amplitude decay. Regions of interest were drawn in pathological and control regions, where IVIM perfusion parameters were compared to the corresponding dynamic susceptibility contrast (DSC) parameters.ResultsHyperperfusion was found in the nonnecrotic or cystic part of two histologically proven glioblastoma multiforme and in two histologically proven glioma WHO grade III, as well as in a brain metastasis of lung adenocarcinoma, in a large meningioma, and in a case of ictal hyperperfusion. A monoexponential decay was found in a territory of acute ischemia, as well as in the necrotic part of a glioblastoma. The IVIM perfusion fraction f correlated well with DSC CBV.ConclusionOur initial report suggests that high‐resolution brain perfusion imaging is feasible with IVIM in the current clinical setting. J. Magn. Reson. Imaging 2014;39:624–632. © 2013 Wiley Periodicals, Inc.
Neural stem and progenitor cells in health and disease
Authors: Ladran Ian , Tran Ngoc , Topol Aaron , Brennand Kristen J. 
Published: September 2013

Neural stem/progenitor cells (NSPCs) have the potential to differentiate into neurons, astrocytes, and/or oligodendrocytes. Because these cells can be expanded in culture, they represent a vast source of neural cells. With the recent discovery that patient fibroblasts can be reprogrammed directly into induced NSPCs, the regulation of NSPC fate and function, in the context of cell‐based disease models and patient‐specific cell‐replacement therapies, warrants review. WIREs Syst Biol Med 2013, 5:701–715. doi: 10.1002/wsbm.1239This article is categorized under:

Developmental Biology > Lineages
Biological Mechanisms > Regulatory Biology
Developmental Biology > Stem Cell Biology and Regeneration
Modifiable Factors to Decrease the Cost of Robotic‐Assisted Procedures
Authors: Nayeemuddin Mohammed , Daley Susan C. , Ellsworth Pamela 
Published: September 2013

AbstractIn 2000, the US Food and Drug Administration approved the da Vinci Surgical System® for use in the United States. Since that time, the number of surgical robotic systems throughout the United States has continued to grow. The costs for using the system include the initial purchase ($1 million to $2.3 million) plus annual maintenance fees ($100,000 to $150,000) and the cost of limited‐use or disposable instruments. Increasing the number of procedures that are performed using the robotic system can decrease the per‐procedure costs. Two modifiable factors that contribute to increasing the annual caseload are increasing the number of surgeons capable of using the system and having a properly educated perioperative nursing team. An educated surgical team decreases turnover time, facilitates proper flow of each surgical procedure, and is able to actively and passively solve intraoperative problems.
Linear shape oscillations and polymeric time scales of viscoelastic drops
Authors: Brenn Günter , Teichtmeister Stephan 
Published: September 2013

AbstractWe study small-amplitude axisymmetric shape oscillations of viscoelastic drops in a gas. The Jeffreys model is used as the rheological constitutive equation of the liquid, which represents a liquid with a frequency-dependent dynamic viscosity. The analysis of the time-dependent deformations caused by the oscillations yields the characteristic equation for the complex frequency, which describes the oscillation frequency and damping rate dependence on the viscous liquid behaviour and the stress relaxation and deformation retardation time scales ${\lambda }_{1} $ and ${\lambda }_{2} $ involved in the viscoelastic material law. The aim of this study is to quantify the influences of the two time scales on the oscillation behaviour of the drop and to propose an experimental method to determine one of the time scales by measuring damped oscillations of a drop. A proof-of-concept experiment is presented to show the potential and limitations of the method. Results show that values of ${\lambda }_{2} / {\lambda }_{1} $ from these measurements are orders of magnitude smaller than typical values used in simulations of viscoelastic flows.
Age and sex differences in the incorporation of EPA and DHA into plasma fractions, cells and adipose tissue in humans
Authors: Walker Celia G. , Browning Lucy M. , Mander Adrian P. , Madden Jackie , West Annette L. , Calder Philip C. , Jebb Susan A. 
Published: September 2013

The aim of the present study was to determine whether age and sex influence both the status and incorporation of EPA and DHA into blood plasma, cells and tissues. The study was a double-blind, randomised, controlled intervention trial, providing EPA plus DHA equivalent to 0, 1, 2 or 4 portions of oily fish per week for 12 months. The participants were stratified by age and sex. A linear regression model was used to analyse baseline outcomes, with covariates for age or sex groups and by adjusting for BMI. The change in outcomes from baseline to 12 months was analysed with additional adjustment for treatment and average compliance. Fatty acid profiles in plasma phosphatidylcholine, cholesteryl esters, NEFA and TAG, mononuclear cells (MNC), erythrocyte membranes, platelets, buccal cells (BU) and adipose tissue (AT) were determined. At baseline, EPA concentrations in plasma NEFA and DHA concentrations in MNC, BU and AT were higher in females than in males (allP< 0·05). The concentrations of EPA in AT (P= 0·003) and those of DHA in plasma TAG (P< 0·01) and AT (P< 0·001) were higher with increasing age. Following 12-month supplementation with EPA plus DHA, adjusted mean difference for change in EPA concentrations in plasma TAG was significantly higher in females than in males (P< 0·05) and was greater with increasing age (P= 0·02). Adjusted mean difference for change in DHA concentrations in AT was significantly smaller with increasing age (P= 0·02). Although small differences in incorporation with age and sex were identified, these were not of sufficient magnitude to warrant a move away from population-level diet recommendations forn-3 PUFA.
Investigation of seasonal variability of vestibular neuronitis
Authors: Koors P D , Thacker L R , Coelho D H 
Published: September 2013

AbstractObjective:To determine if the incidence of vestibular neuronitis displays seasonal variation.Methods:A retrospective case review was performed to determine the monthly and quarterly incidence of vestibular neuronitis over a 36-month period. Incidence values were compiled, and the chi-square test and Rayleigh test for circular means were used to assess for uneven distribution and seasonality, respectively.Results:Fifty-two patients were diagnosed with vestibular neuronitis during the study period. The 2009–2010 study year showed uneven distribution and evidence of seasonality (R = 7.211, p < 0.001). However, the other two study years did not show statistical significance using either the chi-square test or Rayleigh test. In addition, when incidence values were aggregated across all three years of the study, neither the chi-square test nor Rayleigh test showed statistical significance.Conclusion:The present study found minimal evidence of seasonality in the incidence of vestibular neuronitis. These findings are consistent with studies of seasonality observed for other inner-ear disorders thought to be virally mediated.
ΔΗΛΟΣ ἘΚΙΝΉΘΗ: An ‘Imaginary Earthquake’ on Delos in Herodotus and Thucydides
Authors: Rusten Jeffrey S. 
Published: September 2013

AbstractThucydides' and Herodotus' comments on a portentous (and unique) Delian earthquake contain the same phrase, but date the event almost 60 years apart and mutually rule out each other's datings. Two additional problems in these passages – geology demonstrates that Delos has never in fact had an earthquake of any significance and κινεῖν is not the word for an earthquake – point to an explanation for the historians' treatment. They are based on the Delphic oracle quoted by Herodotus which promised to ‘move unmoved Delos’, a paradox based on the island's mythical transition from floating to fixed (Pindar), but liable to confusion with its equally well-known aseismicity. Normally κινεῖν τὰ ἀκίνητα is used of interfering with religious sites; but the oracle's prediction was interpreted as an earthquake, that was assumed to have occurred in due course (although it had not). Both historians accepted the interpretation, but followed different datings since they invested it with different symbolism, Herodotus of the evils of the Persian and subsequent Greek wars, Thucydides of excited anticipation on the eve of the Peloponnesian War, since for him κίνησις meant ‘mobilization’ (1.1).
Social-Interaction Knowledge Translation for In-Home Management of Urinary Incontinence and Chronic Care
Authors: Jansen Lynn , McWilliam Carol L. , Forbes Dorothy , Forchuk Cheryl 
Published: September 2013

RÉSUMÉBien que l’incontinence urinaire peut être géré d’une manière conservatrice, c’est une cause principale de la dégradation des soins de famille dans la maison. Cette étude a examiné les processus d’interaction sociale et de l’application des connaissances (AC) se rapportant à la façon dont la gestion de l’incontinence urinaire (IU) peut être traduit dans les soins à domicile. Les données provenant des entretiens approfondis ont été receuillies auprès d’un échantillon théorique des 23 aidants familiaux, des beneficiaires âgés et des prestataires de soins à domicile. Les comparaisons constantes et les critères d’analyse de Glaser ont été utilisés pour arriver à traduire les connaissances à travers une théorie de fond. Dix sous-themes sont inclus: comment vivre avec le problème; le renforcement de connaissances expérientielles; le développement du confort; l’assouplissement dans une relation de travail; la mutualité nourricière; facilitant l’échange de connaissances; le renforcement de la confiance; l’affinage de connaissances; mettant tous ensemble, et la gestion de soins à domicile. Les résultats sont instructifs pour l’AC au sujet d’IU à la fois dans la théorie et la pratique des soins à domicile, grâce à avoir éclairé comment l’intersubjectivité et les interactions bi-directionelles sont indispensables à l’application des connaissances des soins à domicile chroniques, ce qui sont largement tacites et empiriques.
Secondary Control Belief Combinations (Adjustment and Acceptance) and Well-Being in Older Adults
Authors: Swift Audrey U. , Chipperfield Judith G. 
Published: September 2013

RÉSUMÉPeu d’études sur les personnes âgées ont evalué directement les croyances de contrôle secondaires, défini auparavant par Morling et Evered en 2006 comme une combinaison de l’ajustement psychologique et de l’acceptation. Nous avons classé les personnes âgées (n = 223, M – age de 85 ans, 62% femmes) en trois catégories, selon leurs croyances de contrôle secondaires: l’ajustement psychologique seulement, l’ajustement psychologique et l’acceptation, et ni l’ajustement psychologique ni l’acceptation. Par rapport aux personnes qui ont insisté sur croyances au sujet de l’ajustement psychologique seulement, ceux qui ont souligné une combinaison de croyances de contrôle secondaires—incluant à la fois l’ajustement psychologique et l’acceptation—ont rapporté les émotions positives plus fréquentes, une plus grande satisfaction de vie et les maladies chroniques moins sévères. Nos résultats ont des implications dans les deux contextes, théoriques et appliquées. Théoriquement, nos résultats s’étendent la réflexion contemporaine sur le contrôle secondaire. Dans les paramètres appliqués, ils suggèrent des façons de penser qui peuvent améliorer le bien-être parmi les tres vieux.
Sexual functioning in patients with major depressive disorder in randomized placebo-controlled studies of extended release quetiapine fumarate
Authors: Clayton Anita H. , Locklear Julie C. , Svedsäter Henrik , McIntyre Roger S. 
Published: September 2013

ObjectiveWe evaluated sexual functioning from 6 acute, randomized, placebo-controlled studies (6–10 weeks) of once-daily extended release quetiapine fumarate (quetiapine XR) 50, 150, or 300 mg/day as monotherapy (Studies 1–4) or adjunct therapy (Studies 6–7) in major depressive disorder (MDD).MethodsWe present a pre-planned, non-inferiority analysis of quetiapine XR monotherapy versus placebo using Changes in Sexual Functioning Questionnaire (CSFQ) total score change (Studies 1–4). Post hoc analyses evaluated CSFQ total and domain scores for fixed-dose monotherapy (Studies 1–2), modified fixed-dose (Studies 3–4), and adjunct therapy studies (Studies 6–7). CSFQ data for active comparators (duloxetine [Study 2], escitalopram [Study 4]) are reported.ResultsQuetiapine XR monotherapy was non-inferior to placebo for sexual functioning (least squares mean [LSM] difference in CSFQ score change versus placebo, 0.16 [95% confidence interval: −0.59, 0.92]); LSM change in CSFQ score: 1.90, quetiapine XR (all doses) and 1.73, placebo. LSM differences versus placebo (95% confidence interval): 0.18 (−1.40, 1.75), duloxetine (Study 2); 0.16 (−1.77, 2.10), escitalopram (Study 4). LSM differences with adjunct quetiapine XR 150 mg/day (0.52;p= 0.338) or 300 mg/day (0.22;p= 0.679) were comparable with placebo plus antidepressants. Post hoc all-patient and gender-specific analyses were comparable for CSFQ total scores versus placebo with quetiapine XR 50, 150, or 300 mg/day, duloxetine, and escitalopram.DiscussionLack of negative effects on sexual functioning in patients with MDD may improve treatment acceptability.ConclusionQuetiapine XR (monotherapy or adjunct therapy) had an impact on sexual function that was comparable with placebo.
Using sequential runtime distributions for the parallel speedup prediction of SAT local search
Authors: ARBELAEZ ALEJANDRO , TRUCHET CHARLOTTE , CODOGNET PHILIPPE 
Published: September 2013

AbstractThis paper presents a detailed analysis of the scalability and parallelization of local search algorithms for the Satisfiability problem. We propose a framework to estimate the parallel performance of a given algorithm by analyzing the runtime behavior of its sequential version. Indeed, by approximating the runtime distribution of the sequential process with statistical methods, the runtime behavior of the parallel process can be predicted by a model based on order statistics. We apply this approach to study the parallel performance of two SAT local search solvers, namely Sparrow and CCASAT, and compare the predicted performances to the results of an actual experimentation on parallel hardware up to 384 cores. We show that the model is accurate and predicts performance close to the empirical data. Moreover, as we study different types of instances (random and crafted), we observe that the local search solvers exhibit different behaviors and that their runtime distributions can be approximated by two types of distributions: exponential (shifted and non-shifted) and lognormal.