bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh Hambatan Samping Pengemis Terhadap Kenyamanan Pengguna Jalan pada Simpang Bersinyal Mall SKA Pekanbaru
Authors: Iswahyudi Ricky Dwi , Halim Muhammad Farid , Setyono Yahya Ramadan , Budiharjo Anton , Istiyanto Bambang 
Published: August 2024

This research aims to determine (1) the influence of the presence of beggars on the comfort level of motorists at the SKA Mall Pekanbaru signalized intersection, (2) the factors that beggars prefer at signalized intersections as a place to beg, and (3) find solutions in resolving problems related to side obstacles, in the form of beggars at signalized intersections in Pekanbaru City. This research is experimental. Data was collected using interviews and questionnaires whose reliability and validity had been verified. Data analysis was carried out by calculating cycle time at intersections to determine the income of beggars. Finally, drivers' suggestions for beggars at signalized intersections are described in detail in the questionnaire results. The results of this research are (1) the presence of beggars disturbs the comfort and safety of motorists, (2) The factor causing the presence of beggars at Simpang Mall SKA Pekanbaru is because the average income of each beggar is IDR. 3,600,000.00 to Rp. 14,000,000.00/8 hours, and (3) the solution for beggars at signalized intersections is to enforce the law regarding controlling beggars and increase public awareness not to give beggars money.
ABSTRAK
Penelitian ini bertujuan untuk mengetahui (1) pengaruh keberadaan pengemis terhadap tingkat kenyamanan pengendara di Simpang Bersinyal Mall SKA Pekanbaru, (2) faktor pengemis lebih memilih simpang bersinyal sebagai tempat untuk meminta – minta, dan (3) mencari solusi dalam penyelesaian masalah terkait hambatan samping berupa pengemis di simpang bersinyal Kota Pekanbaru. Penelitian ini adalah penelitian eksperimental. Pengumpulan data dilakukan dengan wawancara dan kuesioner yang telah diverifikasi reliabilitas dan validitasnya. Analisis data dilakukan dengan menghitung siklus waktu pada simpang untuk menentukan pendapatan pengemis. Terakhir, saran pengendara untuk pengemis di persimpangan bersinyal dideskripsikan secara rinci dari hasil kuesioner. Hasil penelitian ini adalah (1) keberadaan pengemis mengganggu kenyamanan dan keamanan pengendara, (2) Faktor penyebab keberadaan pengemis di Simpang Mall SKA Pekanbaru karena jumlah pendapatan yang tinggi rata-rata upah masing-masing pengemis adalah Rp. 3.600.000,00 sampai Rp. 14.000.000,00/8 jam, dan (3) solusi bagi pengemis di simpang bersinyal adalah menegakkan hukum tentang penertiban pengemis dan meningkatkan kesadaran masyarakat untuk tidak memberikan pengemis uang.
POLICY TO REDUCE UNDER TWO STUNTING IN EAST JAVA REGION, INDONESIA: WHO IS THE RIGHT TARGET?
Authors: Laksono Agung Dwi , Muis Early Wulandari , Wulandari Ratna Dwi 
Published: August 2024

Introduction: Currently, 22% of children worldwide are stunted, and more than half live in Asia. Stunting in East Java is still high in several areas, which should have been prevented, given the relatively good resources. Aims: The study analyzes the policy targets for reducing stunting children in East Java. Methods: The study examined 4,541 children. The study analyzed nutritional status, residence, maternal (age, marriage, education, employment, socioeconomic, prenatal class), and child characteristics (age, gender, and early breastfeeding initiation (EIBF)). Results: Children in urban regions were likelier than those in rural regions to experience stunting. Stunted children were more prevalent among mothers of all ages compared to those <20. Lower education correlated with a greater likelihood of having stunted children. Stunted children were 2.410 times more prevalent among married mothers than divorced/widowed mothers (95%CI 2.292-2.534). Stunted infants were 1.062 times more prevalent among unemployed mothers compared to employed mothers (95%CI 1.050-1.075). All socioeconomic levels have a higher probability than the wealthiest to experience stunting. Mothers with prenatal classes were 1.088 times more likely than those without to have stunted kids (95%CI 1.073-1.103). Children aged 12-23 had a greater likelihood of developing stunting than those younger than <12. Boys were 1.286 times more likely than girls to experience stunting (95%CI 1.272-1.300). Children with EIBF had a 1.081 times higher likelihood of experiencing stunting than those without (95%CI 1.069-1.093). Conclusion: The appropriate policy targets for reducing the stunting prevalence were mothers in urban areas, young age, married, poor educated, unemployed, and poor.
RISK FACTOR ANALYSIS OF INCOMPLETE BASIC IMMUNIZATION IN CHILDREN AGED 12-23 MONTHS IN EAST NUSA TENGGARA PROVINCE
Authors: Almeida Denisca , Benyamin Bebengu Yahya , Syahrul Fariani , Hargono Arief 
Published: August 2024

Introduction: Immunization is an effective effort to prevent some dangerous diseases in children. By providing complete basic immunization, it can reduce child mortality. East Nusa Tenggara province reached a low number of complete basic immunization coverage in 2016 (69.29%), increased in 2017 (72.2%), then decreased again in 2018 (51.72%).Aims: of this study is to analyze risk factors for incomplete immunization status in children aged 12-23 months in NTT province. Method. The method used is analytical observational with a cross-sectional design. The data used are secondary data of Basic Health Research 2018. The study population was household members who could be interviewed at the time of Basic Health Research 2018 in the NTT provincial census block area. Total sample was 674 households. The sampling technique used is two stage one phase stratified sampling. The independent variables include mother's age, father's age, mother's education level, father's education level, number of children, residence, AEFI, and ANC. The dependent variable is the incomplete basic immunization status. Results: In this study, it is known that the candidate in the regression test variables are father's age (p value= 0.005), mother's educational level (p value= 0.000), number of children (p value= 0.007), residence (p value= 0.000), and ANC (p value= 0.000). Conclusion: According to this study, most children under two years were not fully immunized (63.2%). And in this research, the candidate variables will then become a prediction model of incomplete immunization status in children 12-23 months in East Nusa Tenggara province.
ONLINE APPLICATION BASED ON KING INTERACTION SYSTEM THEORY TO INCREASE TREATMENT ADHERENCE AND CLINICAL INDICATORS IN TB CHILDREN
Authors: Sari Ethyca , Nur Kristina Tri , Sujianto Untung , Suhartono  , Sakti Hastaning 
Published: August 2024

Introduction: Non-adherence to treatment among TB children in Indonesia varied 40.5%-57.2%. An innovative method of education might improve treatment adherence and clinical recovery of TB children. The aims of this study were to compare the treatment adherence and clinical indicators of TB children who received an intervention using an online application based on King's theory with a conventional method. Methods: This is a quasi-experimental study to educate 55 TB school-age children using a validated online application based on King's interaction system theory, compared with the conventional method in 55 TB children as the control group. The medication regularity and control discipline were observed four times in weeks 2, 4, 6, and 8. Measurements of acid-fast bacilli (AFB) smear sputum examination, TB scoring, chest X-ray examination, level of Hb, and nutritional status were done twice in pre- and post-intervention. Data analysis used chi-square, paired t-test, independent t-test, Mann Whitney, McNemarᵇ. or Wilcoxon test. Results: The results of this study revealed that the intervention group was significantly successful compared to the control group in several indicators, such as increasing treatment adherence (p=0.001), controlling discipline (p=0.001), reducing AFB positive (p=0.001), TB scoring (p=0.001), infiltrate in chest X-ray examination ((p=0.013), and increasing Hb levels (p=0.001). Meanwhile, nutritional status could not be compared because, from the beginning of the study, the nutritional status was unbalanced and benefited the intervention group. Conclusion: The online application based on King's theory has succeeded in increasing medication adherence and clinical improvement of pulmonary TB in children.
Shallow-water Mussels Adapt to Deep-Sea Environment Through Transcriptomic and Metagenomic Insights
Authors: Sun Luyang , Liu Xiaolu , Zhou Li , Wang Hao , Lian Chao , Zhong Zhaoshan , Wang Minxiao , Chen Hao , Li Chaolun 
Published: August 2024

Abstract

Recent studies have unveiled the deep sea as a rich biosphere, populated by species descended from shallow-water ancestors post-mass extinctions. Research on genomic DNA evolution and microbial symbiosis has shed light on how these species thrive in extreme deep-sea conditions. However, early adaptation stages, particularly the roles of conserved genes and symbiotic microbes, remain inadequately understood. This study examined transcriptomic and microbiome changes in shallow-water mussels exposed to deep-sea conditions at the Site-F cold seep in the South China Sea, at a depth of 1,119 m. Results reveal complex gene expression adjustments in stress response, immune defense, homeostasis, and energy metabolism pathways during adaptation. After 10 days of deep-sea exposure, shallow-water mussels and their microbial communities closely resembled those of native deep-sea mussels, demonstrating host and microbiome convergence in response to adaptive shifts. Notably, methanotrophic bacteria, key symbionts in native deep-sea mussels, emerged as a dominant group in the exposed mussels. Host genes involved in immune recognition and endocytosis correlated significantly with the abundance of these bacteria. Overall, our analyses provide novel insights into adaptive transcriptional regulation and microbiome dynamics of mussels in deep-sea environments, highlighting the roles of conserved genes and microbial community shifts in adapting to extreme environments.
A Simplified Liver Perfusion Model, with Applications to Organ Preservation
Authors: Emerson Daniel , Rabin Yoed , Kara Levent Burak 
Published: August 2024

Abstract

Advanced liver preservation strategies could revolutionize liver transplantation by improving access and restoring function to marginal livers. However, developing new cryopreservation protocols requires exploration of a complex design space, further complicated by the scarcity of real human livers to experiment upon. We aim to create computational models of the liver to aid in the development of new cryopreservation protocols. Towards this goal, we present an approach for generating 3D models of the liver vasculature by building upon the space colonization algorithm. Additionally, we introduce the concept of a super lobule which enables a computational abstraction of biological liver lobules. User-tunable parameters allow for vasculatures of varying depth and topology to be generated. In each model, we solve for a common lumped resistance value assigned to the super lobules, allowing the overall physiological blood pressure and flow rate through the liver to be preserved. We demonstrate our approach's ability to maintain consistency between models of varying fidelity. Next, we simulate steady state machine perfusion of the generated models and highlight similarities with experimental observations. Lastly, we demonstrate how the models can be used to quickly test the effect of different boundary conditions when designing perfusion protocols.
Putting piezoelectric sensors into Fano resonances
Authors: Huang Qing-An , Wang Mengting , Huang Jianqiu 
Published: August 2024

Abstract

Piezoelectric resonance sensors are essential to many diverse applications associated with chemical and biological sensing. In general, they rely on continuously detecting the resonant frequency shift of piezoelectric resonators due to analytes accreting on their surfaces in vacuum, gas or fluid. Resolving the small analyte changes requires the resonators with a high quality factor. Here, we propose theoretically and demonstrate experimentally a scheme using a physics concept, i.e., a Fano resonance, to enhance the quality factor rather than optimizing the structure and material of the resonator itself though these are important. The Fano resonance arises due to the interference between a discrete mode and a continuum of modes, leading to the asymmetric and steep dispersion. In our scheme, the as-fabricated piezoelectric sensors are put into the Fano resonance by connecting an external shunt capacitor to them. As a verification case, one-port surface acoustic wave (SAW) resonators on LiNbO3 substrate, incorporating a composite of polymethyl methacrylate (PMMA) and graphene oxide (GO) for humidity sensing, have been fabricated and characterized. We enhance the quality factor by up to a factor of about 8, from 929 for the as-fabricated sensor to 7682 for that with the external shunt capacitor. Our results pave the way for the practical development of piezoelectric resonance sensors with high quality factor.
Temporal Co-Occurrence in a Community of Subtropical Australian Birds
Authors: Hudson Nicholas J. 
Published: August 2024

Abstract

I aimed to better understand the community ecology of sympatric birdlife in subtropical South East Queensland, Australia using patterns of temporal species co-occurrence and principles from network theory. In line with expectation, a hierarchical clustering analysis showed that sampling dates that were successive possesed similar patterns of observed bird species. Interestingly, there is an example of total observed bird biomass being almost identical (38 kg) on successive days in September, but comprising 36 species on the first day yet only 8 on the second, the latter date being dominated by biomass from a single species (Australian Pelican, Pelicanus conspicillatus). Ranking each species on its average pairwise correlation to the other 87 species in the set shows that, unsurprisingly, raptors (such as Whistling Kites, Haliastur splenurus) tend to be enriched at the extreme negative end of the list (hypergeometric enrichment statistic P = 0.00029) indicating their presence is inhibitory to other avian species. On the other hand, Silvereyes (Zosterops lateralis) possess the highest number of total connections, the highest radiality (or ‘network influence’) metric within the inferred co-occurrence network and have the second highest average positive correlation to all other bird species in the set (+0.32). Collectively, this suggests Z. lateralis can be seen as an indicator species whose presence indicates an enhanced likelihood of observing a diversity of other bird species. The use of the PCIT network reconstruction algorithm is demonstrated in ecology for the first time.
Operando spin observation elucidating performance-improvement mechanisms during operation of Ruddlesden–Popper Sn-based perovskite solar cells
Authors: Marumoto Kazuhiro , Chen Yizhou , Yamaguchi Seira , Sato Atsushi , Xue Dong 
Published: August 2024

Abstract

Sn-based perovskite solar cells (PSCs) have attracted attention because of their low environmental impact. Unfortunately, the readily occurring oxidation of Sn2+ inhibits further improvement of their efficiency and stability. Ruddlesden–Popper (RP) Sn-based perovskites are considered promising candidates as absorbers that improve the performance and stability of Sn-based PSCs. However, microscopic understanding of performance-enhancing mechanisms remains insufficient. For this study, electron spin resonance (ESR) spectroscopy measurements were taken of RP Sn-based PSCs with poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) hole-transport layers and (BA0.5PEA0.5)2FA3Sn4I13 perovskite layers to clarify the space-charge region formation mechanism at the PEDOT:PSS/(BA0.5PEA0.5)2FA3Sn4I13 interface. Results indicated electron-barrier formation in the (BA0.5PEA0.5)2FA3Sn4I13 layer near the PEDOT:PSS layer. Moreover, the electron barrier was found to be enhanced during device operation. The enhanced interface band bending reduces interface recombination and thereby improves the device performance. These findings might provide important progress in practical applications of PSCs and might advance the realization of a carbon-neutral society.
Pathogen delivery route impacts disease severity in experimental co-infection of sheep with Mycoplasma ovipneumoniae and Mannheimia haemolytica
Authors: Jacobson Bryan Tegner , Jessica DeWit , LaShae Zanca , Sonar Sobha , Hardy Carol , Throolin Michael , Brewster Patricia , Andujo Kaitlyn , Jones Kerri , Sago Jonathon , Smith Stephen , Bowen Lizabeth , Bimczok Diane 
Published: August 2024

Abstract

M. ovipneumoniae is a respiratory pathogen that can cause mild to moderate pneumonia and reduced productivity in domestic lambs. However, studies on both natural and experimental M. ovipneumoniae infection have reported highly variable clinical signs and pathology. Here, we assessed the impact of administering M. ovipneumoniae to the upper respiratory tract (URT) or to the lower respiratory tract (LRT) of two-months-old specific pathogen-free lambs. Lambs were inoculated with PBS (control) or with ceftiofur-treated nasal wash fluid obtained from sheep with natural M. ovipneumoniae infection, monitored for eight weeks, and subsequently euthanized. All lambs in the URT and LRT groups developed a stable infection with M. ovipneumoniae. M. ovipneumoniae infection led to lower weight gains and mild respiratory disease, with significantly greater effects following LRT inoculation compared to URT inoculation. At necropsy, lambs inoculated via the LRT showed consolidation of the cranial and alveolar, bronchiolar, and interstitial inflammation that was significantly more severe in the LRT compared to the URT group. M. ovipneumoniae loads in the trachea and bronchi also were significantly higher after LRT than URT inoculation. Interestingly, 9/10 inoculated lambs also tested positive for M. haemolytica in nasal swab but not in bronchial swab samples. In summary, our study suggests that bypassing protective mechanisms of the URT by delivering respiratory pathogens to the LRT leads to more severe respiratory disease and lung damage than delivery to the URT. We also confirmed that M. ovipneumoniae significantly enhances the susceptibility of lambs to secondary respiratory pathogens such as M. haemolytica.
Genome-wide identification of Aux/IAA gene family in grape and functional analysis of VaIAA3 in response to cold stress
Authors: Lu Shixiong , Li Ming , Chen Yongjuan , Gou Huiming , Che Lili , Liang Guoping , Mao Juan 
Published: August 2024

Abstract

The Aux/IAA gene is a key gene that regulates auxin signal transduction in plants. Although IAA genes have been characterized in various plant species, the role of the IAA gene in grape cold resistance is unclear. In order to further explore the members of Aux/IAA gene family in grape and their functions, in this study, based on the genomic data of ‘Pinot Noir’ (Vitis vinefera cv. ‘Pinot Noir’) and Shanputao (Vitis amurensis), 25 VvIAA genes and 18 VaIAA genes were identified. The VaIAA genes exhibited different expression patterns under diferent temperature periods by qPCR. VaIAA3 was selected as a candidate gene for further functional analysis because of its high expression level under low temperature stress. The subcellular localization showed that VaIAA3 was localized in the nucleus. Additionally, under 4℃ treatment at 24 h, the relative expression level of VaIAA3, antioxidant enzyme activity, survival rate, and cold responsive genes of the three transgenic lines (OE-1, OE-2, OE-3) were higher, while the contents of relative electrolytic conductivity (REC), malondialdehyde (MDA) and hydrogen peroxide (H2O2) were lower under cold stress. Transcriptome sequencing analysis revealed that the regulation of low temperature resistance in Arabidopsis thaliana (Arabidopsis) by VaIAA3 may be related to auxin, ABA and ethylene. Importantly, heterologous over-expression of VaIAA3 can enhance resistance of Arabidopsis under cold stress, which provides a theoretical basis for further use of IAA3 gene to improve grape agronomic traits.
SYVN1 aggravates esophageal squamous cell carcinoma development by facilitating macrophage M2 polarization and activating NF-κB pathway
Authors: Wang Kang , Yang Nan , Qiu Yuan , Huang Zhao , Shen Yi , Luo Jing 
Published: August 2024

Abstract

Esophageal squamous cell carcinoma (ESCC) is a leading lethal cancer in the digestive system. Tumor-associated macrophages (TAMs) are key participators in ESCC progression. Mounting evidence has testified the regulatory function of Synoviolin (SYVN1) in cancer development. However, the correlation between SYVN1 and TAM polarization remains unclear. As a result, the goal of the present study was to shed light on the new mechanism of SYVN1 in ESCC. It was found that SYVN1 was upregulated at mRNA and protein levels in tissue samples and cells of ESCC. Knockdown of SYVN1 attenuated the malignant behaviors of ESCC cells in vitro and in vivo. Of note, we verified that silencing SYVN1 contributed to the polarization of TAMs into M1 subtype. Moreover, our findings demonstrated that SYVN1 mediated cell pyroptosis through modulating TAM polarization. More than that, we explored the relationship between SYVN1 and pivotal modulatory factors of NF-κB signaling pathway. Our observations revealed that SYVN1 directly bound with DEAD-box helicase 5 (DDX5) and eukaryotic translation elongation factor 1 alpha 2 (eEF1A2) to enhance their expression. Besides, silencing of SYVN1 inhibited the activation of nuclear factor kappa B (NF-κB) pathway, and overexpression of DDX5 or eEF1A2 abolished the role of SYVN1 deficiency in NF-κB pathway. Overall, this study illustrated that SYVN1 induced ESCC progression by promoting the M2 polarization of TAMs and activating NF-κB pathway.
Research on Laser Sintering Powder Bed Model: Analysis of the Effects of Laser Power and Scanning Speed on the Sintering Pool
Authors: Yu Yueqiang , Shen Shaorui , Gao Sheng , Jiang Ting , Qin Tao , Chen Junyuan 
Published: August 2024

Abstract

By combining numerical simulation and experimental testing, the powder bed model was imported into the discrete element software Flow-3D as the initial model to analyze the melting, flow, and solidification processes of powder particles. The study examined the effects of different laser powers, scanning speeds, and energy densities on single-track sintering paths and temperature fields. It described the characteristics of stable, metastable, and unstable sintering pools and discussed the impact of different laser power levels and various parameter combinations at the same energy density on the width and depth of the sintering pool.. It was found that when the laser power is 10W and the scanning speed increases from 1400mm/s to 2200mm/s, the sintering path morphology deteriorates from a stable to a semi-molten state. At a scanning speed of 2000mm/s, as the laser power increases from 8W to 14W, the width and depth of the sintering pool increase. When the laser energy density is constant at 10J/m, there are significant differences in the sintering path formation under different laser power and scanning speed combinations, with the width of the sintering pool increasing as the laser power and scanning speed increase.