bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cardiac Structure and Function in 8‐ to 12‐Year‐Old Children Following In‐Utero Exposure to Preeclampsia (FINNCARE Study)
Authors: Renlund‐Vikström Michelle , Jääskeläinen Tiina J. , Kivelä Anni , Heinonen Seppo , Laivuori Hannele , Sarkola Taisto 
Published: July 2024

Background
We evaluated how elevated blood pressure in children exposed to preeclampsia (PE) impacted on their cardiac structure and function, as well as relations with maternal, gestational, and perinatal factors and child body size and composition.

Methods and Results

A total of 182 PE (46 early‐onset preeclampsia) and 85 unexposed (non‐PE) children were examined in the FINNCARE study 8 to 12 years after the index pregnancy with echocardiography; office, central, and 24‐hour ambulatory blood pressures; and body anthropometrics and composition. PE children had lower right ventricular basal sphericity index (mean difference, −0.26 95% CI, −0.39 to −0.12) and lower mitral lateral
E
′‐wave peak velocity (−1.4 cm/s [95% CI, −2.1 to −0.6]), as well as higher
E
to
E
′ ratio (0.40 [95% CI, 0.15–0.65]) and indexed tricuspid annular plane systolic excursion (0.03 [95% CI, 0.01–0.05]) compared with non‐PE children. These differences were accentuated in early‐onset PE children. Left ventricular mass (LVM) or left atrial volume were not different between PE and non‐PE children. Lean body mass, body fat percentage, and 24‐hour systolic blood pressure were independent predictors of LVM. Lean body mass and body fat percentage were independent predictors of left atrial volume. No significant associations between LVM or left atrial volume and maternal, gestational, or perinatal parameters were found.

Conclusions
Preadolescent PE children display a more globular‐shaped right ventricle with higher longitudinal systolic displacement as well as mildly altered diastolic indices, with the alterations being pronounced in early‐onset preeclampsia. Lean body mass and adiposity are independently related with LVM and left atrial volume, and systolic blood pressure with LVM in both PE and non‐PE children. These unfavorable associations indicate remodeling of cardiac structure in young children also reflected in mild functional changes in PE children.

Registration

URL:
https://www.clinicaltrials.gov
; unique identifier: NCT04676295.
Revisiting Meta-evaluation for Grammatical Error Correction
Authors: Kobayashi Masamune , Mita Masato , Komachi Mamoru 
Published: July 2024

Abstract
Metrics are the foundation for automatic evaluation in grammatical error correction (GEC), with their evaluation of the metrics (meta-evaluation) relying on their correlation with human judgments. However, conventional meta-evaluations in English GEC encounter several challenges, including biases caused by inconsistencies in evaluation granularity and an outdated setup using classical systems. These problems can lead to misinterpretation of metrics and potentially hinder the applicability of GEC techniques. To address these issues, this paper proposes SEEDA, a new dataset for GEC meta-evaluation. SEEDA consists of corrections with human ratings along two different granularities: edit-based and sentence-based, covering 12 state-of-the-art systems including large language models, and two human corrections with different focuses. The results of improved correlations by aligning the granularity in the sentence-level meta-evaluation suggest that edit-based metrics may have been underestimated in existing studies. Furthermore, correlations of most metrics decrease when changing from classical to neural systems, indicating that traditional metrics are relatively poor at evaluating fluently corrected sentences with many edits.
Context-Aware Machine Translation with Source Coreference Explanation
Authors: Vu Huy Hien , Kamigaito Hidetaka , Watanabe Taro 
Published: July 2024

Abstract
Despite significant improvements in enhancing the quality of translation, context-aware machine translation (MT) models underperform in many cases. One of the main reasons is that they fail to utilize the correct features from context when the context is too long or their models are overly complex. This can lead to the explain-away effect, wherein the models only consider features easier to explain predictions, resulting in inaccurate translations. To address this issue, we propose a model that explains the decisions made for translation by predicting coreference features in the input. We construct a model for input coreference by exploiting contextual features from both the input and translation output representations on top of an existing MT model. We evaluate and analyze our method in the WMT document-level translation task of English-German dataset, the English-Russian dataset, and the multilingual TED talk dataset, demonstrating an improvement of over 1.0 BLEU score when compared with other context-aware models.
Bringing the Value Chain for High-Impact Weather Warnings into the Classroom
Authors: Majumdar Sharanya J. , Hoffmann David , Ebert Elizabeth E. , Golding Brian W. 
Published: July 2024

Abstract
University students can learn about weather warnings and contribute to a database for the World Meteorological Organization (WMO) project on value chain approaches to evaluate the end-to-end warning chain. The project offers students a way to understand how information about high-impact weather is created, shared, and used within a complete warning system for a selected event. Their contributions are intended to inform researchers and practitioners on what has and what has not worked well in the warning process. The students use a structured questionnaire designed to collect information on observations, forecasting, hazards, impacts, warning communications, and responses.
Orthanq: transparent and uncertainty-aware haplotype quantification with application in HLA-typing
Authors: Uzuner Hamdiye , Paschen Annette , Schadendorf Dirk , Köster Johannes 
Published: July 2024

Abstract
Background
Identification of human leukocyte antigen (HLA) types from DNA-sequenced human samples is important in organ transplantation and cancer immunotherapy and remains a challenging task considering sequence homology and extreme polymorphism of HLA genes.

Results
We present Orthanq, a novel statistical model and corresponding application for transparent and uncertainty-aware quantification of haplotypes. We utilize our approach to perform HLA typing while, for the first time, reporting uncertainty of predictions and transparently observing mutations beyond reported HLA types. Using 99 gold standard samples from 1000 Genomes, Illumina Platinum Genomes and Genome In a Bottle projects, we show that Orthanq can provide overall superior accuracy and shorter runtimes than state-of-the-art HLA typers.

Conclusions
Orthanq is the first approach that allows to directly utilize existing pangenome alignments and type all HLA loci. Moreover, it can be generalized for usages beyond HLA typing, e.g. for virus lineage quantification. Orthanq is available under https://orthanq.github.io.
Prevalence and factors associated with antenatal depressive symptoms across trimesters: a study of 110,584 pregnant women covered by a mobile app-based screening programme in Shenzhen, China
Authors: Wu Dadong , Chen Siqi , Zhong Xiaoqi , Zhang Jiayi , Zhao Guanglin , Jiang Lei 
Published: July 2024

Abstract
Background
Antenatal depression is a significant public health issue affecting pregnant women both globally and in China. Using data from a mobile app-based screening programme, this study explored the prevalence and factors associated with antenatal depressive symptoms across different trimesters in Shenzhen.

Methods
A retrospective cross-sectional study was conducted on pregnant women who gave birth in any hospital in Shenzhen between July 2021 and May 2022 and underwent depression screening using an official maternal and infant health mobile app at least once during pregnancy. Depressive symptoms were evaluated using the 9-item Patient Health Questionnaire (PHQ-9), with cut-off scores of 5 and 10 for mild and high level of symptoms, respectively. The prevalence for each trimester was determined by calculating the proportion of women scoring 5 or higher. A variety of sociodemographic, obstetric, psychological, and lifestyle factors were assessed for their association with depressive symptoms. Chi-square test and multivariate logistic regression were performed to identify significant predictors.

Results
A total of 110,584 pregnant women were included in the study, with an overall prevalence of depressive symptoms of 18.0% and a prevalence of high-level symptoms of 4.2%. Depressive symptoms were most prevalent in the first trimester (10.9%) and decreased in the second (6.2%) and third trimesters (6.3%). Only a small proportion (0.4%) of women showed persistent depressive symptoms across all trimesters. Anxiety symptoms in early pregnancy emerged as the most significant predictor of depressive symptoms. Other factors linked to an increased risk throughout pregnancy include lower marital satisfaction, living with parents-in-law, experience of negative life events, as well as drinking before and during pregnancy. Factors associated with a reduced risk throughout pregnancy include multiparity and daily physical activity.

Conclusions
This large-scale study provides valuable insights into the prevalence and factors associated with antenatal depressive symptoms in Shenzhen. The findings underscore the need for targeted interventions for high-risk groups and the integration of mental health care into routine antenatal services. Continuous, dynamic monitoring of depressive symptoms for pregnant women and ensuring at-risk women receive comprehensive follow-up and appropriate psychological or psychiatric care are crucial for effectively addressing antenatal depression and improving maternal and infant health outcomes.
Pneumatic retinopexy for primary rhegmatogenous retinal detachment: from a clinical trial to the real-life experience
Authors: Iannetta Danilo , Valsecchi Nicola , Finzi Alessandro , Mastropasqua Rodolfo , Muni Rajeev H. , Fontana Luigi 
Published: July 2024

Abstract
Background
To report real-world outcomes of patients with primary Reghmatogenous Retinal Detachment (RRD) treated with Pneumatic Retinopexy (PnR) according to the indications of the Pneumatic Retinopexy versus Vitrectomy for management of Primary Rhegmatogenous Retinal Detachment Outcomes Randomized Trial (PIVOT) trial.

Methods
Multicenter, retrospective study. Patients treated with PnR for RRD between 2021 and 2023 and a follow-up of at least 6 months were included. Single-procedure anatomical success, final anatomical success, complications, causes of failures, best corrected visual acuity (BCVA) after surgery, and the vision-related quality of life using the 25-Item National Eye Institute Visual Function Questionnaire (NEI VFQ-25) were reported.

Results
A total of 76 eyes of 76 patients were included. Mean age was 60 ± 8.1 years. Primary anatomic reattachment was achieved by 84.3% of patients and final anatomical reattachment after pars plana vitrectomy was obtained in 100% of patients. BCVA improved from 0.32 (20/40) to 0.04 (20/20) logMar (p < 0.001) at 6 months. The main cause of failure was related to the presence of additional (likely missed) retinal breaks (66.6% of cases). Also, primary PnR failure was more frequent in eyes of patients with older age, macular involvement, worse baseline BCVA, greater extent of the RRD, and increased duration from diagnosis to treatment. Overall, the mean NEI-VFQ 25 composite score was 93.9% ± 6.4 at 6 months.

Conclusions
The criteria of the PIVOT trial can be applied to real-world scenarios in the decision-making process for the treatment of primary RRD, with excellent anatomical and functional outcomes.
Impact of class cancellations on parents’ and children’ adaptation following an outbreak of the Omicron variant during the COVID-19 pandemic in Taiwan in April 2022
Authors: Chao Kuo-Yu , Hsiao Tung-Yuan , Chiang Sum-Fu , Cheng Wei 
Published: July 2024

Abstract
Objective
To explore the impact on Taiwanese parents and children following an outbreak of the Omicron variant during the COVID-19 pandemic.

Methods
Data were collected following class cancellations mandated by the Ministry of Education due to an outbreak of the Omicron variant of COVID-19 in April 2022. A national parent organization developed self-report survey questionnaire, “Impact of the Pandemic-related School Closures/Class Cancellations” (IPRSCCC), assessed parents’ perceived impact of school cancellations on their child/children’ and on their adaptation. The online survey was available between May 4 and May 9, 2022, in 20 districts throughout Taiwan.

Results
A total of 2126 parents representing 2592 children responded. Total scores on the IPRSCCC were significantly higher for parents of children whose classes were cancelled (n = 891) compared with parents whose children continued in-person classes (n = 1053). Parents perceived the class cancellations of the child/children disrupted daily routine, learning loss and impacted academic motivation. They also reported emotional stress and no time for rest, which were associated with parental burnout. However for these parents, there were no significant differences in scores between parents living in low and high socioeconomic areas. Only the subscale score for disrupted daily routine was significantly higher for fathers, and emotional stress was significantly higher for parents with two, or ≥ 3 children. When academic impacts were examined using national examination scores for 12th grade students, the percent of students with scores of ≤ 6 in English, Chinese, and mathematics was higher in 2022 than in 2020.

Conclusions
Higher IPRSCCC scores for parents of children whose classes were cancelled provides additional evidence of the impact of disruptions of in-person classes due to the COVID-19 pandemic. Examination scores confirmed class cancellations impacted academic performance.
Exploring food consumption patterns in the province of Kenitra, Northwest of Morocco
Authors: Hindi Zakia , Belfakira Chaimaa , Lafram Amina , Bikri Samir , Benayad Asmaa , EL Bilali Hamid , Bügel Susanne Gjedsted , Srednicka-Tober Dominika , Pugliese Patrizia , Strassner Carola , Rossi Laura , Stefanovic Lilliana , Aboussaleh Youssef 
Published: July 2024

Abstract
Background
Morocco is currently undergoing rapid changes in diets and lifestyles, influenced by globalization and urbanization, leading to a shift away from the Mediterranean diet (MedDiet) toward Western diets.

Objective
Describe and explore the food consumption patterns of the population of Kenitra province and their adherence to the MedDiet using a validated survey.

Method
The current cross-sectional study involved 442 respondents from Kenitra province, comprising individuals aged 18 and above. The survey included a combination of closed and open-ended questions regarding food consumption patterns and socio-demographic characteristics. Adherence to the MedDiet was assessed using the Panagiotakos method to calculate the MedDiet score (MDS). Additionally, each participant’s adherence to the MedDiet was evaluated using a method based on Martínez-González’s approach.

Results
The results indicate that 31% of the participants eat vegetables, 28% eat fruits, and 19% eat wholegrain bread daily. Furthermore, 58% regularly use olive oil in their cooking. Eating out of home (OOH) was high, with popular places being restaurants and cafes (70%), fast food outlets (20%), and workplace canteens (7%). Overall, participants showed moderate adherence to the MedDiet, with a mean MDS of 36.3 ± 19.7.

Conclusions
Promoting healthy eating habits is crucial in Kenitra. With moderate consumption of nutrient-dense foods and the popularity of the MedDiet, targeted interventions and educational initiatives can promote healthy dietary behaviors, improving overall public health.
Empowerment strategies of the Mentor Mother peer support program among mothers who have migrated to Sweden: a photovoice study
Authors: Kåks Per , Målqvist Mats , Tomlinson Mark , Stansert Katzen Linnea 
Published: July 2024

Abstract
Introduction
A peer support intervention using ‘Mentor Mothers’ was implemented for mothers who had migrated to Sweden, living in socially disadvantaged communities. The Mentor Mothers had a high degree of freedom to develop strategies for facilitating empowerment of their clients according to perceived needs. This study aimed to investigate which empowerment facilitation strategies that Mentor Mothers perceived to be relevant, feasible and effective.

Methods
Photovoice was used to generate qualitative data. Participants took photographs of their work which were then discussed during a focus group discussion and six individual semi-structured interviews. Data were analysed using thematic analysis.

Results
Four overarching strategies to facilitate empowerment were identified, corresponding to distinctive perceived needs in the target group: (1) Informative support responded to a need for making sense of the external context, by helping mothers navigate society, the process of parenthood and cultural parenting norms. (2) Practical support addressed a need for managing challenges in daily life, by facilitating contacts with welfare services and authorities and to enhance parenting practices. (3) Psychosocial support addressed a need for improved mental wellbeing, by instilling feelings of safety and security in daily life, relationships and in contacts with public institutions. (4) Motivational support responded to a need for finding fulfilling purpose, by promoting social interaction, encouraging civic engagement and sharing the challenges and successes of others to inspire hope.

Conclusions
These results highlight various aspects of peer support for empowerment facilitation that future interventions targeting immigrant parents can use in their intervention design.
The utilization of renal dialysis: a comprehensive study in Saudi Arabia
Authors: Alghamdi Loujain S. , Alonazi Wadi 
Published: July 2024

Abstract
Background
Understanding the trend of utilization of renal dialysis in Saudi Arabia (SA) is fundamental as it provides a general overview of renal care. The practice of renal dialysis assists in identifying challenges, opportunities, and potential areas for improvement in the provision of the services.

Objectives
This research investigated the utilization of renal dialysis services in SA by exploring the number of renal dialysis centers, hemodialysis machines (HD), and peritoneodialysis patients.

Methods
The dataset for this study was derived from a collaboration between the General Authority of Statistics (GaStat) and the Ministry of Health (MoH), focusing on indicators for renal dialysis centers and patients across health sectors in 2021. Analysis was conducted using MS Excel 365 and IBM SPSS Version 29, incorporating multiple regression techniques. The health sector was treated as the dependent variable. At the same time, the number of hemodialysis (HD) machines and the counts of HD and peritoneal dialysis patients were considered independent variables.

Results
Around 275 renal dialysis centers, over 8000 HD machines, 20,440 HD patients, and 1,861 peritoneal patients were tallied from two resources. The findings revealed a negative relationship between the health sector and several renal dialysis centers and peritoneodialysis patients, as demonstrated by p < 0.05 in multiple regression analysis.

Conclusion
The number of renal dialysis centers influences the availability of HD machines, affecting the number of HD and peritoneodialysis patients. Most national patients preferred MoH over other semi-governmental and private sectors, and vice versa for non-Saudis.
Sarcoidosis-associated pulmonary hypertension due to pulmonary arteries stenosis – a case report
Authors: Sobiecka Malgorzata , Siemion-Szczesniak Izabela , Burakowska Barbara , Kurzyna Marcin , Dybowska Malgorzata , Tomkowski Witold , Szturmowicz Monika 
Published: July 2024

Abstract
Background
Sarcoidosis-associated pulmonary hypertension (SAPH) is listed in Group 5 of the clinical classification of pulmonary hypertension, due to its complex and multifactorial pathophysiology. The most common cause of SAPH development is advanced lung fibrosis with the associated destruction of the vascular bed, and/or alveolar hypoxia. However, a substantial proportion of SAPH patients (up to 30%) do not have significant fibrosis on chest imaging. In such cases, the development of pulmonary hypertension may be due to the lesions directly affecting the pulmonary vasculature, such as granulomatous angiitis, pulmonary veno-occlusive disease, chronic thromboembolism or external compression of vessels by enlarged lymph nodes. Based on the case of a 69-year-old female who developed SAPH due to pulmonary arteries stenosis, diagnostic difficulties and therapeutic management are discussed.

Case presentation
The patient, non-smoking female, diagnosed with stage II sarcoidosis twelve years earlier, presented with progressive dyspnoea on exertion, dry cough, minor haemoptysis and increasing oedema of the lower limbs. Computed tomography pulmonary angiography (CTPA) showed complete occlusion of the right upper lobe artery and narrowing of the left lower lobe artery, with post-stenotic dilatation of the arteries of the basal segments. The vascular pathology was caused by adjacent, enlarged lymph nodes with calcifications and fibrotic tissue surrounding the vessels. Pulmonary artery thrombi were not found. The patient was treated with systemic corticosteroid therapy and subsequently with balloon pulmonary angioplasty. Partial improvement in clinical status and hemodynamic parameters has been achieved.

Conclusions
An appropriate screening strategy is required for early detection of pulmonary hypertension in sarcoidosis patients. Once SAPH diagnosis is confirmed, it is crucial to determine the appropriate phenotype of pulmonary hypertension and provide the most effective treatment plan. Although determining SAPH phenotype is challenging, one should remember about the possibility of pulmonary arteries occlusion.