bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Cyclic Sulfoxides — Garlicnins K1 (I), K2 (II), and H1 (III) — Extracted from Allium sativum.
Authors: Nohara Toshihiro , Fujiwara Yukio , Komota Yusuke , Kondo Yoshihiko , Saku Taiki , Yamaguchi Koki , Komohara Yoshihiro , Takeya Motohiro 
Published: July 2015

AbstractIsolation and structure elucidation of the new cyclic sulfoxides (I)—(III) are described.
ChemInform Abstract: A New DNA‐Intercalative Cytotoxic Allylic Xanthone from Swertia corymbosa.
Authors: Uvarani Chokkalingam , Arumugasamy Karuppannan , Chandraprakash Kumarasamy , Sankaran Mathan , Ata Athar , Mohan Palathurai Subramaniam 
Published: July 2015

AbstractThe title compound (I) is found to be significantly cytotoxic against human cancer cell lines HeLa, HCT116 and AGS and shows weak activity against the normal NIH 3T3 cell line.
ChemInform Abstract: Suzuki—Miyaura Reaction by Heterogeneously Supported Pd in Water: Recent Studies
Authors: Paul Susmita , Islam Md. Mominul , Islam Sk. Manirul 
Published: July 2015

AbstractReview: [process made in the last fifteen years in the Suzuki—Miyaura coupling reaction by heterogeneous palladium catalysis in water; 100 refs.
ChemInform Abstract: Multiphotochromic Molecular Systems
Authors: Fihey Arnaud , Perrier Aurelie , Browne Wesley R. , Jacquemin Denis 
Published: July 2015

AbstractReview: overview of available multiphotochromic compounds which use a variety of photoactive building blocks, their efficiency in terms of multi‐responsiveness and strategies to circumvent the most common limitations; 277 refs.
ChemInform Abstract: Monolayer Protected Gold Nanoparticles with Metal‐Ion Binding Sites: Functional Systems for Chemosensing Applications
Authors: Pezzato C. , Maiti S. , Chen J. L.‐Y. , Cazzolaro A. , Gobbo C. , Prins L. J. 
Published: July 2015

AbstractReview: [58 refs.
Basic, specific, mechanistic? Conceptualizing musical emotions in the brain
Authors: Omigie Diana 
Published: July 2015

ABSTRACTThe number of studies investigating music processing in the human brain continues to increase, with a large proportion of them focussing on the correlates of so‐called musical emotions. The current Review highlights the recent development whereby such studies are no longer concerned only with basic emotions such as happiness and sadness but also with so‐called music‐specific or “aesthetic” ones such as nostalgia and wonder. It also highlights how mechanisms such as expectancy and empathy, which are seen as inducing musical emotions, are enjoying ever‐increasing investigation and substantiation with physiological and neuroimaging methods. It is proposed that a combination of these approaches, namely, investigation of the precise mechanisms through which so‐called music‐specific or aesthetic emotions may arise, will provide the most important advances for our understanding of the unique nature of musical experience. J. Comp. Neurol. 524:1676–1686, 2016. © 2015 Wiley Periodicals, Inc.
Programming Bioactive Architectures with Cyclic Peptide Amphiphiles
Authors: Kuan Seah Ling , Wang Tao , Raabe Marco , Liu Weina , Lamla Markus , Weil Tanja 
Published: July 2015

AbstractWe present a versatile approach for the synthesis of cyclic peptide amphiphiles of the hormone somatostatin (SST) with tunable lipophilic tails to program bioactive nanoarchitectures. A novel bis‐alkylation reagent is synthesized that facilitates the functionalization of SST with a thiol anchor. Different hydrophobic moieties are introduced inspired by a biomimetic palmitoylation approach which opens access to cyclic peptide amphiphiles that display rich self‐organization and cell membrane interactions.
The Effects of Bug‐in‐the‐Eye Supervision on Therapeutic Alliance and Therapist Competence in Cognitive‐Behavioural Therapy: A Randomized Controlled Trial
Authors: Weck Florian , Jakob Marion , Neng Julia M. B. , Höfling Volkmar , Grikscheit Florian , Bohus Martin 
Published: July 2015

Live supervision enables a supervisor to have direct insight into the psychotherapeutic process and allows him or her to provide immediate feedback to the trainee. Therefore, live supervision might be superior to traditional supervisory formats that only allow for the provision of delayed feedback. When considering the different live supervision formats, bug‐in‐the‐eye (BITE) supervision is particularly promising because of its improved and less invasive procedure. The current study compared the efficacy of BITE supervision with that of delayed video‐based (DVB) supervision. In the present study, 23 therapists were randomly assigned to either the BITE supervision or DVB supervision groups. The participants were psychotherapy trainees who treated 42 patients (19 under BITE supervision and 23 under DVB supervision) over 25 sessions of cognitive‐behavioural therapy. Two independent raters blind to the treatment conditions evaluated therapeutic alliance and therapist competence based on 195 videotapes. Therapeutic alliance was significantly stronger among the treatments conducted under BITE supervision than those conducted under DVB supervision. Moreover, a higher level of therapeutic competence was found in the BITE condition than in the DVB condition. However, no differences between supervision conditions were found when the results were controlled for the level of therapeutic alliance and therapist competence demonstrated in the first session. No differences were observed between the supervision conditions with respect to patient outcomes. There is evidence that BITE supervision is able to improve therapeutic alliance and therapist competence. However, these findings should be interpreted with caution because possible pre‐treatment differences between therapists might explain the superiority of BITE supervision. Copyright © 2015 John Wiley & Sons, Ltd.Key Practitioner Message

BITE supervision positively influences the therapeutic alliance and therapeutic competencies during cognitive‐behavioural therapy.
A supervision format that more directly addresses therapeutic processes is more effective in improving those processes than an indirect supervision format.
Pre‐treatment differences between therapists might explain the superiority of BITE supervision.
BITE supervision can be considered a safe intervention.
Accuracy of implant surgery with surgical guide by inexperienced clinicians: an in vitro study
Authors: Toyoshima Takeshi , Tanaka Hideaki , Sasaki Masanori , Ichimaru Eiji , Naito Yasushi , Matsushita Yasuyuki , Koyano Kiyoshi , Nakamura Seiji 
Published: July 2015

AbstractImplant surgery with surgical guide has been introduced with a concept of position improvement. The surgery might be considered as easy even for inexperienced clinician because of step simplicity. However, there are residual risks, resulting in postoperative complications. The aim of this study was to assess the accuracy of implant surgery with surgical guide by inexperienced clinicians in in vitro. After preoperative computed tomographies (CTs) of five artificial models of unilateral free‐end edentulism with scan templates, five surgical guides were established from templates. Following virtual planning, 10 implants were placed in the 45 and 47 regions by five residents without any placement experiences. All drillings and placements were performed using surgical guides. After postoperative CTs, inaccurate verifications between virtual and actual positions of implants were carried out, by overlaying of pre/postoperative CT data. The angle displacement of implant axis in the 47 region was significantly larger than that in the 45 region (P = 0.031). The 3D offset of implant base in the 47 region was significantly larger than that in the 45 region (P = 0.002). For distal/apical directions, displacements of base in the 47 region were significantly larger than those in the 45 region (P = 0.004 andP = 0.003, respectively). The 3D offset of implant tip in the 47 region was significantly larger than that in the 45 region (P = 0.003). For distal/apical directions, displacements of tip in the 47 region were significantly larger than those in the 45 region (P = 0.002 andP = 0.003, respectively). Within limitations of this in vitro study, data for accuracy of implant surgery with surgical guide would be informative for further studies, because in vitro studies should be substantially made to avoid unnecessary burden of patients, in advance of retro/prospective studies. A comparison of the accuracy in this in vitro model between by inexperienced and well‐experienced operators should be necessary for clinicians intending to use surgical guide for placement.
Design of recursive digital integrators and differentiators using particle swarm optimization
Authors: Jalloul Manal K. , Al‐Alaoui Mohamad Adnan 
Published: July 2015

SummaryThis paper presents a new method for designing digital recursive integrators and differentiators by using nonlinear stochastic global optimization based on particle swarm optimization (PSO). A modified PSO is used to optimize the unknown coefficients of second‐order and third‐order recursive integrators in order to obtain a better magnitude response closer to the ideal integrator. The coefficients of the state‐of‐the‐art available filters in the literature are chosen as initial points in the PSO process. By choosing a good starting point, convergence to an optimal solution is greatly facilitated. A dynamic modification of the fitness function used in the PSO process leads to the design of a set of digital integrators each optimized for a specific frequency range. Then, second‐order and third‐order recursive digital differentiators are designed by inverting and stabilizing the transfer functions of the designed recursive integrators. The obtained stabilized differentiators are further optimized using PSO to further improve their performance. The magnitude responses of the designed filters outperform the existing integrators and differentiators. Copyright © 2015 John Wiley & Sons, Ltd.
Adaptive fuzzy multiple attribute decision routing in VANETs
Authors: Li Gen , Ma Maode , Liu Chunfeng , Shu Yantai 
Published: July 2015

SummaryVehicular ad hoc networks (VANETs) have attracted much research attentions in the recent years. Although there are many outstanding solutions of geographic routing designed for the VANETs, only one or two features of the VANETs have been specifically utilized in each of the proposed solutions. In this paper, we propose a novel adaptive fuzzy multiple attribute decision routing (AFMADR) scheme, by which a packet carrier is supposed to be a decision maker in the selection of a target for the next hop transmission with more factors to be considered. The AFMADR scheme consists of four steps. Firstly, the candidate vehicles are characterized by four attributes including the distance, the direction, the road density, and the location to obtain a fuzzy attribute score of each attribute. Secondly, according to the real‐time conditions of the candidates' attributes, weights of attributes will be calculated by the proposed adaptive weight algorithm, which makes the AFMADR scheme more scalable and robust in different VANET scenarios. Then, a fuzzy performance score will be produced for each candidate based on the fuzzy attribute score and their real‐time weights. Lastly, a route decision is made by choosing a candidate with the highest performance score as the target for the next hop transmission. We carry out simulation experiments to compare the performance of the AFMADR scheme with the existing well‐known geographic routing protocols for the VANETs. The simulation results demonstrate that the proposed AFMADR scheme can achieve the best performance in terms of the highest delivery ratio and the lowest delivery delay with a reasonable number of hops among all protocols in all the simulation scenarios. Copyright © 2015 John Wiley & Sons, Ltd.
Dynamics of a rumor‐spreading model with diversity of configurations in scale‐free networks
Authors: Hosseini Soodeh , Abdollahi Azgomi Mohammad , Torkaman Rahmani Adel 
Published: July 2015

SummaryIn this paper, we propose a new rumor‐spreading model, which is a variant of the susceptible–exposed–infectious–removed epidemic model. We consider the influences of the diversity of configurations as a defense strategy to diminish the damage brought by rumor diffusion. The diversity of configuration can be found in different instant messengers or social networks. Moreover, we apply two kinds of the rumor immunization strategies such as random immunization and targeted immunization and show that targeted immunization is better than random immunization for rumor‐spreading control in scale‐free networks. We carry out the systematic analysis of the model and study the local and global stability of rumor‐free equilibrium. In the proposed model, we introduce two new states, namely, hibernator and stifler2, to study dynamical behaviors of the model. The proposed model combines both targeted immunization and diversity of configuration to prevent rumor spreading. By numerical simulations, we indicate that our model is appreciably better than other models in terms of declining the rumor diffusion speed. Furthermore, we investigate many related dynamic properties to make the result more complete. Simulation results show the effect of different parameters on the rumor diffusion in scale‐free networks; meanwhile, numerical simulations confirm the theoretical solution. Copyright © 2015 John Wiley & Sons, Ltd.
High grade endometrial stromal sarcoma on thinprep
Authors: Ginter Paula S. , Pirog Edyta C. , Hoda Rana S. 
Published: July 2015

High grade endometrial stromal sarcoma (HGESS) is an uncommon malignancy recently re‐defined in the new WHO classification of endometrial stromal tumors. In this article, we discuss the differential diagnoses of metastatic HGESS in a fine needle aspiration (FNA) of a lymph node and compare the cytomorphology of HGESS in ThinPrep [(TP), Hologic Inc., Boxborough, MA] to conventional smears (CS).The patient had a history of stage I HGESS, status‐post supracervical hysterectomy without regional lymph node metastases. Her post‐operative course was complicated by pelvic fluid collections and enlarging para‐aortic lymph nodes. Diff‐Quik (DQ)‐stained and Papanicolaou (Pap)‐stained smears from a para‐aortic lymph node FNA demonstrated a cellular specimen with monomorphic population of plump to oval cells with scant, wispy cytoplasm in aggregates and as single cells. The nuclei showed fine chromatin and small inconspicuous nucleoli. Compared to the CS, HGESS cells in the TP showed similar cytological features, with the exception that the nuclei were slightly smaller, hyperchromatic, and the chromatin pattern was attenuated.In the absence of prior clinical history, the cytomorphology of metastatic HGESS in a lymph node can be difficult to differentiate from a lymphoma, a variety of metastatic spindle cell tumors or metastatic carcinoma. Immunohistochemical analysis and comparison with the primary tumor can be useful in proving the nature of the malignant cells. The cytomorphology of HGESS on TP correlated well in both single cells and aggregates when compared to CS. The differences noted were decreased nuclear size, nuclear hyperchromasia, and slightly attenuated nuclear detail on TP. Diagn. Cytopathol. 2015;43:756–762. © 2015 Wiley Periodicals, Inc.
Helicobacter pylori infection is associated with type 2 diabetes among a middle‐ and old‐age Chinese population
Authors: Han Xu , Li Yaru , Wang Jing , Liu Bing , Hu Hua , Li Xiulou , Yang Kun , Yuan Jing , Yao Ping , Wei Sheng , Wang Youjie , Liang Yuan , Miao Xiaoping , Zhang Xiaomin , Guo Huan , Yang Handong , Wu Tangchun , He Meian 
Published: July 2015

AbstractBackgroundAlthough the association of Helicobacter pylori (H. pylori) infection with diabetes mellitus has been evaluated, findings are controversial. This study investigated the association in a Chinese population.MethodsA cross‐sectional study, including a total of 30 810 subjects from the Dongfeng‐Tongji Cohort study, was conducted. H. pylori status was measured via 14C urea breath test. Association analysis was performed by logistic regression, with multivariable adjustment for sex, age, body mass index, smoking, alcohol consumption, family history of diabetes, physical activity and the use of antibiotics.ResultsAmong a middle‐age and old‐age Chinese population, individuals with H. pylori infection also had a higher prevalence of type 2 diabetes (21.3% versus 20.2%, p = 0.026). H. pylori infection was associated with higher risk of type 2 diabetes [odds ratio, 1.08 (95% confidence interval: 1.02–1.14); p = 0.008] after adjustment for other confounders. The association was significant among women, those who were above 65 years old, not overweight or obese, and those who did not smoke, did not consume alcohol and without family history of diabetes. However, there was no interaction between H. pylori infection and other traditional risk factors on type 2 diabetes risk. Subjects with H. pylori infection had a lower level of high‐density lipoprotein cholesterol (p < 0.0001) and higher levels of blood pressure (p < 0.001), total cholesterol, HbA1c and fasting blood glucose (p < 0.0001) than those who did not.ConclusionsThese findings suggested that H. pylori infection was associated with the risk of type 2 diabetes in a middle‐age and old‐age Chinese population. Copyright © 2015 John Wiley & Sons, Ltd.
Grhl2 is required in nonneural tissues for neural progenitor survival and forebrain development
Authors: Menke Chelsea , Cionni Megan , Siggers Trevor , Bulyk Martha L. , Beier David R. , Stottmann Rolf W. 
Published: July 2015

SummaryGrainyhead‐like genes are part of a highly conserved gene family that play a number of roles in ectoderm development and maintenance in mammals. Here we identify a novel allele of Grhl2, cleft‐face 3 (clft3), in a mouse line recovered from an ENU mutagenesis screen for organogenesis defects. Homozygous clft3 mutants have a number of phenotypes in common with other alleles of Grhl2. We note a significant effect of genetic background on the clft3 phenotype. One of these is a reduction in size of the telencephalon where we find abnormal patterns of neural progenitor mitosis and apoptosis in mutant brains. Interestingly, Grhl2 is not expressed in the developing forebrain, suggesting this is a survival factor for neural progenitors exerting a paracrine effect on the neural tissue from the overlying ectoderm where Grhl2 is highly expressed. genesis 53:573–582, 2015. © 2015 Wiley Periodicals, Inc.
Overview of genetic research in anorexia nervosa: The past, the present and the future
Authors: Brandys Marek K. , de Kovel Carolien G.F. , Kas Martien J. , van Elburg Annemarie A. , Adan Roger A.H. 
Published: July 2015

ABSTRACTBackgroundEven though the evidence supporting the presence of a heritable component in the aetiology of anorexia nervosa (AN) is strong, the underlying genetic mechanisms remain poorly understood. The recent publication of a genome‐wide association study (GWAS) of AN (Boraska, Mol Psychiatry, 2014) was an important step in genetic research in AN.ObjectiveTo briefly sum up strengths and weaknesses of candidate‐gene and genome‐wide approaches, to discuss the genome‐wide association studies of AN and to make predictions about the genetic architecture of AN by comparing it to that of schizophrenia (since the diseases share some similarities and genetic research in schizophrenia is more advanced).MethodDescriptive literature review.ResultsDespite remarkable efforts, the gene‐association studies in AN did not advance our knowledge as much as had been hoped, although some results still await replication.DiscussionContinuous effort of participants, clinicians and researchers remains necessary to ensure that genetic research in AN follows a similarly successful path as in schizophrenia. Identification of genetic susceptibility loci provides a basis for follow‐up studies. © 2015 Wiley Periodicals, Inc. (Int J Eat Disord 2015; 48:814–825)
Predictors of treatment outcome in individuals with eating disorders: A systematic review and meta‐analysis
Authors: Vall Eva , Wade Tracey D. 
Published: July 2015

ABSTRACTObjectiveUnderstanding the factors that predict a favourable outcome following specialist treatment for an eating disorder may assist in improving treatment efficacy, and in developing novel interventions. This review and meta‐analysis examined predictors of treatment outcome and drop‐out.MethodA literature search was conducted to identify research investigating predictors of outcome in individuals treated for an eating disorder. We organized predictors first by statistical type (simple, meditational, and moderational), and then by category. Average weighted mean effect sizes (r) were calculated for each category of predictor.ResultsThe most robust predictor of outcome at both end of treatment (EoT) and follow‐up was the meditational mechanism of greater symptom change early during treatment. Simple baseline predictors associated with better outcomes at both EoT and follow‐up included higher BMI, fewer binge/purge behaviors, greater motivation to recover, lower depression, lower shape/weight concern, fewer comorbidities, better interpersonal functioning and fewer familial problems. Drop‐out was predicted by more binge/purge behaviors and lower motivation to recover. For most predictors, there was large interstudy variability in effect sizes, and outcomes were operationalized in different ways. There were generally insufficient studies to allow analysis of predictors by eating disorder subtype or treatment type.DiscussionTo ensure that this area continues to develop with robust and clinically relevant findings, future studies should adopt a consistent definition of outcome and continue to examine complex multivariate predictor models. Growth in this area will allow for stronger conclusions to be drawn about the prediction of outcome for specific diagnoses and treatment types.
Mindfulness and eating behavior in adolescent girls at risk for type 2 diabetes
Authors: Pivarunas Bernadette , Kelly Nichole R. , Pickworth Courtney K. , Cassidy Omni , Radin Rachel M. , Shank Lisa M. , Vannucci Anna , Courville Amber B. , Chen Kong Y. , Tanofsky‐Kraff Marian , Yanovski Jack A. , Shomaker Lauren B. 
Published: July 2015

ABSTRACTObjectiveThe purpose of this investigation was to examine the relationship of dispositional mindfulness to binge eating and associated eating attitudes and behaviors among adolescent girls at risk for type 2 diabetes (T2D).MethodsParticipants were 114 overweight or obese adolescents enrolled in a study of girls with a family history of T2D and mild depressive symptoms. Adolescent self‐reports of mindfulness, eating in the absence of hunger, and depressive symptoms were collected. An interview was administered to determine presence of binge eating episodes and a behavioral task was used to assess the reinforcing value of food relative to other nonsnack food rewards. Body composition was assessed using dual‐energy X‐ray absorptiometry.ResultsIn analyses accounting for race, percent body fat, lean mass, height, age, and depressive symptoms, dispositional mindfulness was associated with a lower odds of binge eating (p = .002). Controlling for the same potential confounds, mindfulness was also inversely associated with eating concern, eating in the absence of hunger in response to fatigue/boredom, and higher food reinforcement relative to physical activity (all p < .05).DiscussionIn girls with a family history of T2D, independent of body composition and depressive symptoms, intraindividual differences in mindfulness are related to binge eating and associated attitudes and behaviors that may confer risk for obesity and metabolic problems. Further research is needed to determine the extent to which mindfulness plays a role in the etiology and/or maintenance of disinhibited eating in adolescents at risk for T2D. © 2015 Wiley Periodicals, Inc. (Int J Eat Disord 2015; 48:563–569)