bluuebunny/crossref_metadata_2025_split huggingface dataset:
Computerized cognitive behaviour therapy for depression in people with a chronic physical illness
Authors: Sharp John , Holly Deirdre , Broomfield Niall 
Published: December 2012

PurposeComputerized cognitive behaviour therapy (cCBT) is becoming an increasingly well‐recognized therapeutic option for the treatment of depression. With acknowledged high prevalence of depression within chronic physical ill‐health populations and a need to increase access to psychological therapies, cCBT represents a low‐intensity intervention with the potential to have great utility within health care settings.MethodsThis article systematically reviews the evidence for the effectiveness of cCBT for the treatment of depression with people who have a chronic physical health problem. A comprehensive search was conducted to identify relevant randomized, controlled trials. Identified studies were quality‐assessed, and data were extracted by two reviewers.ResultsOne study investigating cCBT for the treatment of depression in people with diabetes fulfilled inclusion criteria. The trial reported positive outcomes compared to a waiting‐list control condition.ConclusionsThe available literature suggests cCBT programmes may be beneficial for populations with a chronic physical illness experiencing depression. This conclusion is based on the findings of a single study, which involved the evaluation of a cCBT package by its developers, included a short follow‐up and featured specialist health care support. Additionally, the study reported considerable attrition suggesting the intervention might not have been acceptable to many participants. It is likely that cCBT may be a way in which to increase access to psychological therapies. However, prior to any definitive conclusions being made, further high‐quality research to establish the acceptability, feasibility, efficacy, and effectiveness of cCBT for specific chronic physical health conditions is required.Statement of contributionWhat is already known on this subject? Computerized cognitive behaviour therapy (cCBT) is increasingly being utilized as a low‐intensity treatment for depression within general adult populations following positive randomized, controlled trials of both commercial and free‐to‐use programmes. There is potential application for such programmes in addressing the high prevalence of depression within physically ill populations. However, to date, there has been no attempt to review the literature regarding the application of cCBT to treat depression in people with a chronic physical illness.What does this study add?

Fifty‐six studies were identified and screened for inclusion in the present systematic review.
One RCT, applying cCBT to a diabetes population, fulfilled inclusion criteria.
Development of complex interventions should be guided by a recognized flexible, phased framework.
Left Ventricular Ejection Fraction and Left Ventricular End‐Diastolic Volume in Patients With Diastolic Dysfunction
Authors: Jovin Ion S. , Ebisu Keita , Liu Yi‐Hwa , Finta Laurie A. , Oprea Adriana D. , Brandt Cynthia A. , Dziura James , Wackers Frans J. 
Published: December 2012

Diastolic dysfunction can be diagnosed on equilibrium radionuclide angiocardiography (ERNA) by a low peak filling rate (PFR) in the setting of a normal left ventricular ejection fraction (LVEF). The authors evaluated the relationship between diastolic dysfunction, LVEF, and end‐diastolic volume (EDV). A total of 408 predominantly asymptomatic patients with an LVEF ≥50% by ERNA were studied. LVEF of patients with a low PFR was compared with the LVEF of patients with a normal PFR. Correlation analyses to evaluate the association between PFR and EDV were also performed. The LVEF of patients with a low PFR was lower than the LVEF of patients with normal PFR (59±7 vs 63%±7%; P<.01). There was no correlation between EDV and PFR (r=−0.04; P=.32). The results did not change when the EDV indices were used. In patients who had repeat scans, there was no correlation between the change in EDV and the change in PFR (r=0.16; P=.2). In asymptomatic patients undergoing ERNA who have normal systolic function, a low PFR can be associated with a lower LVEF, but it is not associated with changes in EDV. This suggests that diastolic dysfunction is associated with mild systolic dysfunction.
Association of clinical events with everolimus exposure in kidney transplant patients receiving reduced cyclosporine
Authors: Shihab Fuad S. , Cibrik Diane , Chan Laurence , Kim Yu Seun , Carmellini Mario , Walker Rowan , Zibari Gazi , Pattison James , Cornu‐Artis Catherine , Wang Zailong , Tedesco‐Silva Jr Helio 
Published: December 2012

AbstractBackgroundThe association between clinical events and everolimus exposure in patients receiving reduced‐exposure calcineurin inhibitor therapy is poorly explored.MethodsIn a pre‐planned, descriptive analysis of data from a randomized controlled trial, events were correlated with everolimus trough concentrations in 556 newly transplanted kidney transplant patients receiving everolimus with reduced‐exposure cyclosporine (CsA) and steroids. Influence of everolimus exposure on clinical events was stratified according to predefined time‐normalized concentrations.ResultsThe incidence of treated biopsy‐proven acute rejection and graft loss at month 12 was highest in patients with everolimus <3 ng/mL (36.4% and 28.6%, respectively, vs. 9.1–15.3% and 0.9–5.0% with higher concentration ranges). A higher mortality rate was observed in patients with an everolimus trough concentration ≥12 ng/mL (10.0% vs. 1.7–5.6% with lower concentration ranges). The lowest rates of renal dysfunction (defined as poor renal function [estimated GFR, serum creatinine] or proteinuria), wound healing events, peripheral edema, new‐onset diabetes mellitus, hypercholesterolemia and hypertriglyceridemia were generally observed with everolimus trough concentration in the range 3–8 ng/mL and CsA <100 ng/mL. Proteinuria occurred most frequently in patients with very low or very high everolimus trough concentrations.ConclusionsThese results support an exposure–response relationship between clinical events and everolimus trough concentrations in kidney transplant patients receiving reduced‐exposure CsA.
Intensive therapy following upper limb botulinum toxin A injection in young children with unilateral cerebral palsy: a randomized trial
Authors: Hoare Brian , Imms Christine , Villanueva Elmer , Rawicki Hyam Barry , Matyas Thomas , Carey Leeanne 
Published: December 2012

AimBotulinum toxin A (BoNT‐A) combined with occupational therapy is effective in improving upper limb outcomes in children with unilateral cerebral palsy (CP). It is now essential to identify the most effective therapies following BoNT‐A. Given the added burden for children and families, the aim of this study was to explore whether modified constraint‐induced movement therapy (mCIMT) leads to sufficiently superior gains compared with bimanual occupational therapy (BOT) in young children with unilateral CP following BoNT‐A injections.MethodIn this randomized, controlled, evaluator‐blinded trial, 34 children (20 males, 14 females; mean age 3y, SD 1y 4mo, range 18mo–6y) with unilateral CP were randomized using concealed allocation to one of two 8‐week interventions. The experimental group (n=17) received BoNT‐A and mCIMT. The comparison group (n=17) received BoNT‐A and BOT. Participants were recruited from a physical rehabilitation clinic and randomized between August 2003 and May 2009. Primary outcome was measured using the Assisting Hand Assessment at 3 months. Secondary outcomes were measured at 3 months and 6 months using the Quality of Upper Extremity Skills Test, the Pediatric Evaluation of Disability Inventory, Canadian Occupational Performance Measure, and the Goal Attainment Scale.ResultsThere were no clinically important differences between groups at baseline. Immediately following intervention, there was no evidence of a superior effect for BoNT‐A + mCIMT as determined by the Assisting Hand Assessment (estimated mean difference [EMD] 0.81, upper 95% confidence limit 3.6; p=0.32) or secondary outcomes. However, both groups showed improvement over time (BoNT‐A + mCIMT: EMD 2.7, 95% confidence interval [CI] 0.7–5.2; BONT‐A + BOT: EMD 4.7, 95% CI 2.1–8.6). Follow‐up at 6 months also demonstrated no superior effect for BoNT‐A + mCIMT.InterpretationFollowing upper limb injection of BoNT‐A, there was no evidence that mCIMT, despite the significantly increased intensity of the home programme, produced a superior effect across a range of outcomes compared with a structured programme of BOT in young children with unilateral CP.
Value Creation in Scene‐based Music Production: The Case of Electronic Club Music in Germany
Authors: Lange Bastian , Bürkner Hans‐Joachim 
Published: December 2012

AbstractThe focus of this article is on the variability of value creation in the popular music industry. Recent trends in electronic music have been based on both the valorization of global tastes and of local specialities in performance and production. Depending on musical styles and market niches, local scenes have become important forces behind heterogeneous “globalocal” markets. At the same time, technological change and the virtualization of music production and distribution contribute to increasingly differentiated configurations of value creation. It is therefore necessary to reconstruct theoretically and empirically the new interplay among the local music production, digital media markets, and virtual communities that are involved. On the basis of empirical explorations in a German hot spot of electronic club‐music production (the city of Berlin), the article indentifies local interaction practice and constellations of stakeholders. The findings show that value creation in these rapidly changing production scenes has moved away from the large‐scale distribution of producer‐induced media to audience‐induced live performance and interactive soundtrack production. This change involves the rising importance of cultural embeddings such as taste building, reputation building among artists and producers, and local community building. Starting from an open theoretical problematization of value creation with regard to fluid scenes and shifting modes of production, the results of first empirical reconstructions are taken as inputs to an evolving discussion on the configurations of value creation in consumer‐based strands of music production.
A preliminary assessment of the response of a native reptile assemblage to spot‐spraying invasive Bitou Bush with glyphosate herbicide
Authors: Martin Leigh J. , Murray Brad R. 
Published: December 2012

SummaryDuring recent work examining the effects of Bitou Bush (Chrysanthemoides monilifera ssp. rotundata) invasion on native reptile assemblages in coastal heathland vegetation in Eastern Australia, unplanned spot‐spraying of glyphosate occurred at some of our experimental sites invaded by Bitou Bush. We used this unexpected herbicide application as an opportunity to provide a preliminary assessment of the short‐term impacts on reptiles of glyphosate spot‐spraying of Bitou Bush. Using an M‐BARCI design, we compared reptile assemblages among uninvaded (reference) sites, invaded (control) sites and invaded and sprayed (impact) sites before and after spraying. We found no significant short‐term (7 – 10 months) differences in reptile abundance, species richness or assemblage composition among invaded, uninvaded and sprayed sites before and after glyphosate application. We cautiously interpret our results to generate a preliminary finding that spot‐spraying of Bitou Bush with glyphosate appears not to have a deleterious effect on reptile assemblages at seven and ten months following herbicide application. While we would not recommend basing management decisions on the outcomes of our study alone, we suggest that our findings can be used to assist in the development of strategic analyses of glyphosate impacts on native flora and fauna.
First record of the onion psyllid Bactericera tremblayi (Wagner, 1961) in France (Insecta: Hemiptera: Sternorrhyncha: Psylloidea), new symptoms on leek crops and reassessment of the B. nigricornis‐group distribution
Authors: Ouvrard D. , Burckhardt D. 
Published: December 2012

The triozid Bactericera tremblayi, or onion psyllid, is recorded for the first time from France, and is associated for the first time with important damage on leek crops in several regions of the country. We compare the morphology of this species with the two other species of the B. nigricornis‐group, in order to avoid misidentifications, and illustrate the different stages of B. tremblayi. The published distribution of the three species is summarised and updated based on collection data, and the presence of B. tremblayi and B. trigonica in Jordan and Spain (Canary Islands) respectively, is also recorded for the first time.
Hepatic vein waveform and splenomegaly predict improvement of prothrombin time after splenectomy in hepatitis C virus‐related cirrhotic patients
Authors: Kinjo Nao , Nagao Yoshihiro , Akahoshi Tomohiko , Masahiro Kamori , Hashimoto Naotaka , Uehara Hideo , Kawanaka Hirohumi , Tomikawa Morimasa , Shirabe Ken , Hashizume Makoto , Maehara Yoshihiko 
Published: December 2012

AimWhether hepatic function can recover in cirrhotic patients after splenectomy remains controversial.MethodsAll consecutive Japanese patients with hepatic cirrhosis due to hepatitis C who had undergone elective splenectomy in Kyushu University Hospital between January 2008 and December 2009 were included in this retrospective study. Prothrombin time, serum albumin and total bilirubin concentrations were reviewed before and after splenectomy and analyzed to clarify whether splenectomy improves hepatic function in patients with cirrhosis and to determine the factors predictive of improvement in hepatic function.ResultsProthrombin time and total serum bilirubin concentration improved after splenectomy; however, serum albumin concentrations did not increase significantly. Twelve months after splenectomy, total serum bilirubin had decreased by over 0.3 mg/dL in 52.3% of patients and prothrombin time had improved by over 10% in 52.3% of patients. Multiple linear regression analysis identified hepatic vein waveform (HVWF) type I (P = 0.0174) and spleen weight (P = 0.0394) as independent predictors of improvement in prothrombin time and preoperative total serum bilirubin (P = 0.0002) as the only independent predictor of decrease in total bilirubin. Total bilirubin and prothrombin time were significantly improved after splenectomy in patients with HVWF type I, however, they were not improved in patients with HVWF type II.ConclusionProthrombin time and total bilirubin improve in approximately half of cirrhotic patients within a year after splenectomy. HVWF type I and splenomegaly may be predictive factors for improvement in prothrombin time after splenectomy in patients with cirrhosis due to hepatitis C.
Fiscal Sustainability and Immigration in the Madrid Region
Authors: Doncel Luis Miguel , Durá Pedro , Grau Pilar , Sainz Jorge 
Published: December 2012

AbstractThe growing number of immigrants in the Madrid region raises several questions concerning the welfare of future native generations. The debates shift from increasing concern about the congestion of public services like education or healthcare, to how immigration helps to ease tension in relation to financing those services and other benefits to the region's general welfare. In order to evaluate the global effect, our analysis uses a generational accounting method which is applied to different productivity, interest rate and growth scenarios. The results show that the impact of immigrants is positive, with intergenerational distribution towards the currently most active taxpayers.
Chronic leg ulcers in adult patients with rheumatological diseases – a 7‐year retrospective review
Authors: Chia Hui Y , Tang Mark BY 
Published: December 2012

AbstractChronic leg ulcers in patients with rheumatological diseases can cause significant morbidity. We performed a retrospective case review to describe the epidemiology, clinical features and outcome of chronic leg ulcers in this group of patients. Twenty‐nine patients with underlying rheumatological conditions, such as, rheumatoid arthritis (15 patients), systemic lupus erythematosus (8 patients), overlap syndromes (3 patients), systemic sclerosis (1 patient) and ankylosing spondylitis (1 patient) were included. The ulcers were mostly located around the ankle (55·2%) and calves (37·9%). The predominant aetiology of the ulcers, in decreasing order of frequency, was venous disease, multifactorial, vasculitis or vasculopathy, infective, pyoderma gangrenosum, ischaemic microangiopathy and iatrogenic. Treatment modalities included aggressive wound bed preparation, compression therapy (17 patients), changes in immunosuppressive therapy (15 patients), hyperbaric oxygen therapy (4 patients) and cellular skin grafting (2 patients). Management of chronic leg ulcers in rheumatological patients is challenging and the importance of careful clinicopathological correlation and treatment of the underlying cause cannot be overemphasised.
An Extension of Virtual Globe to Build On‐Demand Geospatial Data Sharing Capability Using Peer‐to‐Peer Technology
Authors: Liu Yi , Li Bin , Fan Liwei 
Published: December 2012

AbstractIn the virtual globe system, ever higher performance is demanded for high quality service, especially when requesting intensive data from large‐scale networks, such as large scene 3D city models with fine textures. Extending the virtual globe platform from the present centralized mode into a decentralized mode can significantly improve platform capacity and service quality without additional investment in hardware, but presents new challenges such as the time cost of finding a peer, unstable offering, and low service capacity. A GeoODP2P network is designed based on specific features of spatial data transmission. Next, we discuss peer selection mechanisms that relieve the negative influence of peers, and propose a pre‐fetch mechanism that takes advantage of the unique characteristics of the P2P environment. This article implements a simulation system for a GeoODP2P network and presents a prototype platform that incorporates P2P functionality. Peer selection and pre‐fetch mechanisms are studied and tested on this simulation system. The prototype platform run in a real scenario demonstrates the effectiveness of applying P2P to a virtual globe platform.
A Parallel Framework for Processing Massive Spatial Data with a Split–and–Merge Paradigm
Authors: Guan Xuefeng , Wu Huayi , Li Lin 
Published: December 2012

AbstractDue to high data volume, massive spatial data requires considerable computing power for real‐time processing. Currently, high performance clusters are the only economically viable solution given the development of multicore technology and computer component cost reduction in recent years. Massive spatial data processing demands heavy I/O operations, however, and should be characterized as a data‐intensive application. Data‐intensive application parallelization strategies, such as decomposition, scheduling and load‐balance, are much different from that of traditional compute‐intensive applications. In this article we introduce a Split‐and‐Merge paradigm for spatial data processing and also propose a robust parallel framework in a cluster environment to support this paradigm. The Split‐and‐Merge paradigm efficiently exploits data parallelism for massive data processing. The proposed framework is based on the open‐source TORQUE project and hosted on a multicore‐enabled Linux cluster. A specific data‐aware scheduling algorithm was designed to exploit data sharing between tasks and decrease the data communication time. Two LiDAR point cloud algorithms, IDW interpolation and Delaunay triangulation, were implemented on the proposed framework to evaluate its efficiency and scalability. Experimental results demonstrate that the system provides efficient performance speedup.
A Multi‐granularity Parallel Model for Unified Remote Sensing Image Processing WebServices
Authors: Guo Wei , Zhu Xinyan , Hu Tao , Fan LiWei 
Published: December 2012

AbstractThe growth of the Web has resulted in the Web‐based sharing of distributed geospatial data and computational resources. The Geospatial Processing Web (GeoPW) described here is a set of services that provide a wide array of geo‐processing utilities over the Web and make geo‐processing functionalities easily accessible to users. High‐performance remote sensing image processing is an important component of the GeoPW. The design and implementation of high‐performance image processing are, at present, an actively pursued research topic. Researchers have proposed various parallel strategies for single image processing algorithm, based on a computer science approach to parallel processing. This article proposes a multi‐granularity parallel model for various remote sensing image processing algorithms. This model has four hierarchical interfaces that are labeled the Region of Interest oriented (ROI‐oriented), Decompose/Merge, Hierarchical Task Chain and Dynamic Task interfaces or sub‐models. In addition, interfaces, definitions, parallel task scheduling and fault‐tolerance mechanisms are described in detail. Based on the model and methods, we propose an open‐source online platform named OpenRS‐Cloud. A number of parallel algorithms were uniformly and efficiently developed, thus certifying the validity of the multi‐granularity parallel model for unified remote sensing image processing web services.
Measures of the Economic Value of Probabilities of Bankruptcy
Authors: Johnstone D. J. , Jones S. , Jose V. R. R. , Peat M. 
Published: December 2012

SummaryFinancial institutions and regulatory agencies direct much effort and expertise towards estimating probabilities of bankruptcy. By comparison, the techniques that are used to evaluate probability estimates have attracted little attention and remain somewhat ad hoc. The most common approach is to count misclassifications, based on an arbitrary classification threshold. Some use is made of conventional probability score functions, such as the Brier score (from meteorology) but these are not standard practice. Our purpose is to introduce a family of economic probability score functions designed to capture the utility obtained by a user, with a specified utility function, who uses the estimated probabilities to make hypothetical bets against a rival forecaster or model. The conceptual appeal of these score functions is that probability forecasts are evaluated neither in abstract, nor in isolation, but by whether they would hypothetically have ‘made money’ for a given user, with specified risk aversion, against comparable forecasts or market betting prices.