bluuebunny/crossref_metadata_2025_split huggingface dataset:
Book Reviews
Authors: Mandala Elias , Leeming Mark , Jundt Thomas , Eiden Herbert , McIsaac Jacqueline 
Published: March 2013

Abstract
Wapulumuka O. Mulwafu, Conservation Song: A History of Peasant- State Relations and the Environment in Malawi, 1860-2000 (Elias Mandala)
David Kinkela, DDT and the American Century: Global Health, Environmental Politics, and the Pesticide that Changed the World (Mark Leeming)
Sarah S. Elkind, How Local Politics Shape Federal Policy: Business, Power, and the Environment in Twentieth-Century Los Angeles (Thomas Jundt)
Peter Borsay and John K. Walton (eds.), Resorts and Ports: European Seaside Towns since 1700 (Herbert Eiden)
Stephanie Spencer, Francis Bedford, Landscape Photography and Nineteenth-Century British Culture: The Artist as Entrepreneur (Jacqueline McIsaac)
Association of Gastroesophageal Factors and Worsening of Forced Vital Capacity in Systemic Sclerosis
Authors: Zhang Xuli Jerry , Bonner Ashley , Hudson Marie ,   The Canadian Scleroderma Research Group, Baron Murray , Pope Janet 
Published: April 2013

Objective.Interstitial lung disease (ILD) is a common complication of systemic sclerosis (SSc) and causes death. Once lung fibrosis occurs, disease course may become stable or decline. Little is known about risks for progression. We studied SSc–gastroesophageal (GE) involvement in relation to worsening forced vital capacity (FVC) on pulmonary function tests (PFT) to investigate whether it was related to progression. Our objective was to determine whether GE reflux and dysphagia are associated with progressive moderate/severe ILD as measured by PFT over 3 years.Methods.The Canadian Scleroderma Research Group is a multicenter SSc database that collects data annually. Using indicators of GE involvement and annual PFT, comparisons were made between no/mild ILD, stable moderate/severe ILD, and progressive moderate/severe ILD groups based on changes of FVC. Multivariate analyses determined associations between GE factors and ILD development and progression.Results.There were 1043 patients with SSc (mean age 55.7 yrs, mean disease duration 10.8 yrs); one-quarter had pulmonary fibrosis on chest radiograph that was related to FVC percentage predicted (Spearman’s rho −0.39; p < 0.01). Physician indicators such as esophageal dysmotility (p = 0.009) and postesophageal dilatation (p = 0.041), and patient indicators such as difficulty swallowing (p = 0.016) and waking up choking (p = 0.026) were associated with low FVC. In comparing progressive and stable moderate/severe FVC (< 70% predicted), early satiety (p = 0.018) and a combination term of postdilatation and choking (p = 0.042) increased risk of progression of ILD. Topoisomerase I was not associated with progression over followup.Conclusion.Symptoms of esophageal dysmotility were associated with worsening FVC in SSc, especially if both need for esophageal dilatation and choking were present.
Efficacy and Safety of Belimumab in Patients with Rheumatoid Arthritis: A Phase II, Randomized, Double-blind, Placebo-controlled, Dose-ranging Study
Authors: Stohl William , Merrill Joan T. , McKay James D. , Lisse Jeffrey R. , Zhong Z. John , Freimuth William W. , Genovese Mark C. 
Published: April 2013

Objective.To evaluate the efficacy/safety of belimumab in patients with rheumatoid arthritis (RA).Methods.Patients fulfilling American College of Rheumatology (ACR) criteria for RA for ≥ 1 year who had at least moderate disease activity while receiving stable disease-modifying antirheumatic drug (DMARD) therapy and failed ≥ 1 DMARD were randomly assigned to placebo or belimumab 1, 4, or 10 mg/kg, administered intravenously on Days 1, 14, and 28, and then every 4 weeks for 24 weeks (n = 283). This was followed by an optional 24-week extension (n = 237) in which all patients received belimumab. Primary efficacy endpoint was the Week 24 ACR20 response.Results.Week 24 ACR20 responses with placebo and belimumab 1, 4, and 10 mg/kg were 15.9%, 34.7% (p = 0.010), 25.4% (p = 0.168), and 28.2% (p = 0.080), respectively. Patients taking any belimumab dose who continued with belimumab in the open-label extension had an ACR20 response of 41% at 48 weeks. A similar ACR20 response (42%) at 48 weeks was seen in patients taking placebo who switched in the extension to belimumab 10 mg/kg. Greater response rates were observed in patients who at baseline were rheumatoid factor-positive, anticitrullinated protein antibody-positive, or tumor necrosis factor inhibitor-naive, or had elevated C-reactive protein levels, Disease Activity Score 28 > 5.1, or low B lymphocyte stimulator levels (< 0.858 ng/ml). Adverse event rates were similar across treatment groups.Conclusion.In this phase II trial, belimumab demonstrated efficacy and was generally well tolerated in patients with RA who had failed previous therapies. [ClinicalTrials.gov identifier NCT00071812]
Cardiovascular Events Are Not Associated with MTHFR Polymorphisms, But Are Associated with Methotrexate Use and Traditional Risk Factors in US Veterans with Rheumatoid Arthritis
Authors: Davis Lisa A. , Cannon Grant W. , Pointer Lauren F. , Haverhals Leah M. , Wolff Roger K. , Mikuls Ted R. , Reimold Andreas M. , Kerr Gail S. , Richards J. Steuart , Johnson Dannette S. , Valuck Robert , Prochazka Allan , Caplan Liron 
Published: April 2013

Objective.C677T and A1298C polymorphisms in the enzyme methylenetetrahydrofolate reductase (MTHFR) have been associated with increased cardiovascular (CV) events in non-rheumatoid arthritis (RA) populations. We investigated potential associations of MTHFR polymorphisms and use of methotrexate (MTX) with time-to-CV event in data from the Veterans Affairs Rheumatoid Arthritis (VARA) registry.Methods.VARA participants were genotyped for MTHFR polymorphisms. Variables included demographic information, baseline comorbidities, RA duration, autoantibody status, and disease activity. Patients’ comorbidities and outcome variables were defined using International Classification of Diseases-9 and Current Procedural Terminology codes. The combined CV event outcome included myocardial infarction (MI), percutaneous coronary intervention, coronary artery bypass graft surgery, and stroke. Cox proportional hazards regression was used to model the time-to-CV event.Results.Data were available for 1047 subjects. Post-enrollment CV events occurred in 97 patients (9.26%). Although there was a trend toward reduced risk of CV events, MTHFR polymorphisms were not significantly associated with time-to-CV event. Time-to-CV event was associated with prior stroke (HR 2.01, 95% CI 1.03–3.90), prior MI (HR 1.70, 95% CI 1.06–2.71), hyperlipidemia (HR 1.57, 95% CI 1.01–2.43), and increased modified Charlson-Deyo index (HR 1.23, 95% CI 1.13–1.34). MTX use (HR 0.66, 95% CI 0.44–0.99) and increasing education (HR 0.87, 95% CI 0.80–0.95) were associated with a lower risk for CV events.Conclusion.Although MTHFR polymorphisms were previously associated with CV events in non-RA populations, we found only a trend toward decreased association with CV events in RA. Traditional risk factors conferred substantial CV risk, while MTX use and increasing years of education were protective.
Patterns and Associated Risk of Perioperative Use of Anti-Tumor Necrosis Factor in Patients with Rheumatoid Arthritis Undergoing Total Knee Replacement
Authors: Johnson Beverly K. , Goodman Susan M. , Alexiades Michael M. , Figgie Mark P. , Demmer Ryan T. , Mandl Lisa A. 
Published: April 2013

Objective.The patterns and risks of perioperative use of anti-tumor necrosis factor (anti-TNF) medication in patients with rheumatoid arthritis (RA) are not well studied. We examined the patterns of perioperative anti-TNF use and risk of postoperative adverse events (AE) in patients undergoing total knee replacement (TKR).Method.Retrospective cohort study with followup. RA cases within a TKR registry were identified by ICD-9 code (714.0) or self-report. Mailed questionnaires queried anti-TNF use and duration of RA. AE were determined by chart review and patient self-report, and included surgical site infection, pulmonary embolus, deep venous thrombosis, pneumonia, and any infection or re-operation within 6 months.Results.There were 268 TKR cases with RA. The stop time for anti-TNF preoperatively correlated with dosing schedule; restart time was after wound healing. There were 7 surgical site infections (3%), one (0.4%) of which was a deep joint infection in bilateral TKA requiring explant. The anti-TNF group had 3.26% (3/92) local site infection versus 2.10% (3/143) in the group without anti-TNF and this difference was not statistically significant (Fisher exact test, p = 0.68). The one deep joint infection was in the anti-TNF group. Six-month AE rate was 7.61% in the anti-TNF group versus 6.99% in the group without anti-TNF (Fisher exact test, p = 1.0).Conclusion.There was a low risk of infection and perioperative adverse events in patients with RA receiving anti-TNF therapy who were undergoing TKR. This raises the question whether it is necessary to stop anti-TNF for a long period prior to surgery. Given the possible risks associated with stopping anti-TNF, including worsening of disease, further study is needed to determine optimal perioperative use of anti-TNF among patients with RA undergoing TKR.
Politiques publiques de développement à la frontière franco-brésilienne : une ignorance mutuelle
Authors: d’Hautefeuille Madeleine Boudoux 
Published: April 2013

De nombreux espaces frontaliers périphériques des États nationaux font l’objet, de par le monde, de politiques publiques de développement territorialisées. La frontière franco-brésilienne, entre la Guyane française, département-région d’outre-mer français, et l’Amapá, État fédéré brésilien, constitue le cas d’étude sur lequel nous examinons ici ces politiques en nous intéressant non à leur efficacité mais à leur coïncidence. Cet examen révèle un différentiel politique majeur entre France et Brésil : s’appuyant sur des logiques nationales mises en place depuis le milieu du XXe siècle, mais aussi dotées de quelques spécificités locales, elles n’ont ni la même portée géographique, ni la même nature, ni les mêmes objectifs, ni les mêmes types de pilotes.En s’appuyant prioritairement sur l’analyse des documents de politiques publiques connexes, cet article revient successivement sur celles mises en œuvre du côté français et du côté brésilien, pour aboutir à un bilan tabulaire et cartographique comparatif mettant en exergue de nets écarts et une relative ignorance mutuelle.
Multidimensional Vinogradov-type Estimates in Function Fields
Authors: Kuo Wentang , Liu Yu-Ru , Zhao Xiaomei 
Published: April 2013

AbstractLet 𝔽q[t] denote the polynomial ring over the finite field 𝔽q. We employ Wooley's new efficient congruencing method to prove certain multidimensional Vinogradov-type estimates in 𝔽q[t]. These results allow us to apply a variant of the circle method to obtain asymptotic formulas for a system connected to the problem about linear spaces lying on hypersurfaces defined over 𝔽q[t].
A Critical Review of the Approved Mental Health Professional Role and Occupational Therapy
Authors: Knott Gill , Bannigan Katrina 
Published: March 2013

Introduction: A major amendment to the Mental Health Act 2007 was to broaden the professional groups eligible to undertake specific roles under the Act. One such role was the approved mental health professional (AMHP), whose responsibility is to conduct assessments of people deemed mentally disordered to determine whether they meet the criteria for detention, known as ‘sectioning’. Traditionally, this role was undertaken by social workers. Although occupational therapists are now eligible to undertake the role, uptake has been low. Method: A critical literature review was conducted to explore the AMHP role and occupational therapy in order to develop an understanding of the fit between the two. A wide-ranging search identified 282 articles, 30 of which were relevant to the review question. Findings: Coding identified four overarching interrelated themes: values, social (work) perspective, independence of the AMHP role and impact on therapeutic relationship. Coherence exists between social work values and occupational therapy values so it is more likely that structural issues, rather than incongruent values, are impeding occupational therapists' uptake of the AMHP role. Conclusion: A register of occupational therapists employed as AMHPs, and further research exploring reasons for low uptake, is recommended.
Code Sets for Everyday Life Situations of Children Aged 0–6: Sleeping, Mealtimes and Play — A Study Based on the International Classification of Functioning, Disability and Health for Children and Youth
Authors: Adolfsson Margareta , Björck-Åkesson Eva , Lim Chih-Ing 
Published: March 2013

Introduction: The complexity of the Child and Youth version of the International Classification of Functioning, Disability and Health, the ICF-CY, is a challenge for occupational therapists and other professionals in clinical work. Code sets including only essential categories help to make it more user-friendly. Thus far, code sets have been developed to reflect functioning for children in different developmental periods. However, there are no code sets that support screening of participation in everyday life situations and can be used across diagnoses. This exploratory study is the first attempt to develop code sets for preschoolers' (age 0–6 years) everyday life situations. Method: Using sequential Delphi processes with expert panels consisting of 35 professionals in five interdisciplinary early intervention teams and six parents of children, the study identified content in three code sets: Sleeping, Mealtimes and Play. Results: A limited number of relevant categories were identified for three code sets: Sleeping (12), Mealtimes (21) and Play (30). Findings suggested a professional focus on Environmental factors compared with a parental focus on Body functions. Conclusion: It is important to consider the opinions of all involved when developing code sets to provide a common framework for screening of children's everyday functioning.
The Large Allen Cognitive Level Screen as an Indicator for Medication Adherence among Adults Accessing Community Mental Health Services
Authors: Cairns Alice , Hill Cathy , Dark Frances , McPhail Steven , Gray Marion 
Published: March 2013

Background: Medication remains the cornerstone treatment for mental illness. Cognition is one of the strongest predictors of non-adherence. The aim of this preliminary investigation was to examine the association between the Large Allen Cognitive Level Screen (LACLS) and medication adherence among a small sample of mental health service users to determine whether the LACLS has potential as a screening tool for capacity to manage medication regimens. Method: Demographic and clinical information was collected from a small sample of people who had recently accessed community mental health services. Participants then completed the LACLS and the Medication Adherence Rating Scale (MARS) at a single time point. The strength of association between the LACLS and MARS was examined using Spearman rank-order correlation. Results: A strong positive correlation between the LACLS and medication adherence (r = 0.71, p = 0.01) was evident. No participants reported the use of medication aids despite evidence of impaired cognitive functioning. Conclusion: This investigation has provided the first empirical evidence indicating that the LACLS may have utility as a screening instrument for capacity to manage medication adherence among this population. While promising, this finding should be interpreted with caveats given its preliminary nature.
Participation in Day Centres for People with Psychiatric Disabilities — A Focus on Occupational Engagement
Authors: Tjörnstrand Carina , Bejerholm Ulrika , Eklund Mona 
Published: March 2013

Background: Day centres are central for community participation among people with mental health problems. Understanding day centre attendees' occupational engagement is therefore important. Method: A total of 88 people from six day centres in four municipalities in southern Sweden completed a time-use diary, recording their occupational engagement during the most recent day at the day centre. The transcribed data were analysed using thematic content analysis. Findings: The main theme was being part of the spirit of togetherness and getting empowered, from which the participants' reflections could be understood. Conclusion: The day centres provided opportunities to be occupationally engaged and to create routines, and challenged the attendees to be more active in their daily life. Day centres have the potential to provide empowering occupations and rehabilitation for people with mental health problems and to help them towards a more participatory life.
Políticas Educativas y modos de trabajo docente en Argentina: un recorrido por las imposiciones y resistencias entre la reproducción y la emancipación
Authors: Imen Pablo 
Published: April 2013

El artículo se propone analizar algunas de las posibles elaciones entre la política educativa y el trabajo docente en Argentina, a partir de una reconstrucción histórica de las relaciones entre la normativa que sucesivamente reguló al sistema educativo y su mutua imbricación con la labor de los enseñantes. El análisis de las relaciones entre políticas y prácticas intentó incorporar tanto las imposiciones gubernamentales como las respuestas de los docentes, especialmente de aquellos que asumiendo posiciones de rebeldía desplegaron prácticas pedagógicas contrahegemónicas. El punto de partida es el período fundacional del Sistema Educativo Formal en Argentina y se continúa con la recomposición operada fundamentalmente en la década del noventa. El análisis se propone recuperar las relaciones entre la macro y la micropolítica así como relevar algunas de las disputas que se operan entre las imposiciones y las resistencias en el plano de la tarea pedagógica.
Los maestros de Educación básica en México (D.F.) ante la reestructuración del sector educativo
Authors: Dieguez José David Alarid 
Published: April 2013

En el presente trabajo se abordan las formas en las que la reestructuración en el sector educativo en México que, se ha traducido en la implementación de políticas educativas “modernizadoras”, ha incidido en la reconfiguración de las condiciones laborales de los maestros de educación básica en México y con ello se ha afectado la manera en que acometen su labor. La reestructuración en curso ha seguido las pautas marcadas por organismos internacionales como el BM y el FMI, destacadamente, entre otras, nuevas políticas de retribución diferencial del trabajo docente. Asimismo, se analizan las estrategias con las que los profesores de educación básica de la Ciudad de México han afrontado las consecuencias que ellos viven como negativas de la reforma educativa para su trabajo y la educación pública.
Advocate Generals’ Opinions or Separate Opinions? Judicial Engagement in the CJEU
Authors: Turenne Sophie 
Published: March 2013

AbstractIn this article, we challenge that assumption that the Court of Justice of the European Union does not need to accommodate dissenting opinions because the necessary arguments and policy perspectives can be outlined in the AG’s Opinion. We examine the greater legitimacy that may be gained from permitting dissenting and concurring opinions in cases which involve the determination of fundamental rights before the Court. We ultimately argue that our discussion on the quality of judgments is closely related to a discussion on the selection process and criteria for membership of the Court. In the current context, however, the AG’s Opinions continue to provide a more robust field for articulating national and European norms and a larger space for interpretive innovation than the Court’s ordinary forum.
‘Posting’ and ‘Posted Workers’: The Need for Clear Definitions of Two Key Concepts of the Posting of Workers Directive
Authors: van Hoek Aukje , Houwerzijl Mijke 
Published: March 2013

AbstractIn this chapter the authors discuss the personal scope of the Directive on the Posting of Workers (Dir 96/71/EC) and the implementation thereof in the Member States. The comparative findings are based on two studies conducted by the authors on behalf of the European Commission in 2010/2011. The authors argue that the concepts of ‘posting’ and ‘posted worker’ are crucial for a proper understanding of the scope of application of the Directive and its interaction with the Rome I Regulation on the applicable law to contractual obligations (Reg 593/2008). A clear and enforceable demarcation of the personal scope will help the Member States to combat abuse of the freedom to provide services and to distinguish more clearly between posting and other types of labour mobility. The proposal submitted by the European Commission to that effect (COM (2012) 131) is judged to be an important step in the right direction.
The Advocate General: Assisting the CJEU of Article 13 TEU to Secure Trust and Democracy
Authors: Solanke Iyiola 
Published: March 2013

AbstractThe Advocate General (AG) has been a permanent feature of the European Union judicial order since 1957. From two Advocates General (AGs) in a Community of six Member States and Court of seven judges, their number has risen to eight in a Union of 27 Member States, three courts and 61 judges. Their task under the Treaty has remained the same, as has their mode of recruitment. The Lisbon Treaty has, however, assigned a new task to the collective judiciary of the Union—under Article 13 TEU, it is to ‘serve’ the citizens of the EU. What does this mean, and in particular what does it mean for the AG—has the task of these non-decision making officers also changed? This chapter suggests that the objective of this new duty is to manufacture trust in the Court of Justice and argues that this requires more transparency at the CJEU and thus a new role for the Advocate General.
Up in the Air: Aviation, the EU Emissions Trading Scheme and the Question of Jurisdiction
Authors: Voigt Christina 
Published: March 2013

AbstractFrom 1 January 2012, all flights departing from or arriving at the European Union are covered by the EU Emissions Trading Scheme (EU ETS). Amendments were made to Directive 2003/87/EC by Directive 2008/101/EC with the objective of reducing climate change impacts attributable to aviation, but also in order to avoid distortions of competition. The scheme now includes all airlines, including those from third countries, and accounts for emissions that occur partly outside the airspace of EU Member States. A large number of third countries claim that the extension of the Emissions Trading Scheme to legs of flights outside EU territory violates the principle of state sovereignty and deny the jurisdiction of the EU to regulate emissions that occur beyond its borders. So far, the validity of the EU regulation has been challenged by a claim brought by US and Canadian air carriers. They contended that, in adopting the Directive, the EU infringed principles of customary international law—in particular the principle of state sovereignty and the prohibition of extraterritorial application—as well as various international agreements. On 21 December 2011, the Court of Justice of the European Union ruled that the inclusion of emissions from aviation in the EU ETS is valid. In response, Chinese and Indian carriers threatened not to pay the charge, while US airlines pledged to consider other options. This chapter analyses the judgment of the Court and the opinion of Advocate General Kokott in this case. Particular attention is given to the question of extraterritorial jurisdiction and the understanding of state sovereignty in the context of global climate change mitigation. The chapter argues that the Court missed an opportunity to contribute to the clarification of the law on jurisdiction and to the development of climate law.