bluuebunny/crossref_metadata_2025_split huggingface dataset:
A qualitative exploration of the unmet psychosocial rehabilitation needs of cancer survivors in China
Authors: Wang Ji‐Wei , Shen Qian , Ding Ning , Zhang Tian‐Rui , Yang Zhi‐Qi , Liu Cong , Chen Si‐Jia , Berry Helen Louise , Yuan Zheng‐Ping , Yu Jin‐Ming 
Published: November 2015

AbstractObjectiveThis study explores the unmet psychosocial rehabilitation needs of cancer survivors.MethodsSixty‐eight cancer survivors from the Shanghai Cancer Rehabilitation Club in China participated in one of the eight focus groups. These were transcribed verbatim, coded using thematic analysis and analysed using NVivo 10.ResultsFive main themes were identified: the need for (1) better information: Chinese cancer survivors find it difficult to sort and evaluate the overwhelming mass of information with which they are confronted; (2) psychological support: survivors fear cancer relapse and neighbours' discrimination against them; support from other cancer survivors can relieve the stress; (3) support for survivors' families: like the survivors, family members are under great but usually unacknowledged pressure; (4) improved health and medical services: community health service centres provide little medical, informational or psychological support for cancer survivors, who seek and expect more communication with doctors; and (5) assistance with the financial burden: costs of treatment and lack of adequate medical insurance cause substantial financial pressure for survivors.ConclusionsThis study shows that, in addition to their illness, Chinese cancer survivors experience a range of stresses related to their financial circumstances, lack of reliable and summarised information, poor access to support and services (including for their families) and discrimination. Support from families seems to improve survivors' ability to cope. Cancer survivors (and their families) need an integrated package of support from their families, doctors and other service providers, hospitals and communities. These findings can inform approaches to continuing care for cancer survivors. Copyright © 2015 John Wiley & Sons, Ltd.
Da Vinci single site© surgical platform in clinical practice: a systematic review
Authors: Morelli Luca , Guadagni Simone , Di Franco Gregorio , Palmeri Matteo , Di Candio Giulio , Mosca Franco 
Published: November 2015

AbstractBackgroundThe Da Vinci single‐site© surgical platform (DVSSP) is a set of single‐site instruments and accessories specifically dedicated to robot‐assisted single‐site surgery.MethodsThe PubMed database from inception to June 2015 was searched for English literature on the clinical use of DVSSP in general surgery, urology and gynecology.ResultsTwenty‐nine articles involving the clinical application of DVSSP were identified; 15 articles on general surgery (561 procedures), four articles on urology (48 procedures) and 10 articles on gynecology (212 procedures). All studies have proven the safety and feasibility of the use of DVSSP. The principal reported advantage is the restoration of intra‐abdominal triangulation, while the main reported limitation is the lack of the endowrist.ConclusionsDa Vinci systems have proven to be valuable assets in single‐site surgery, owing to the combination of robot use with the dedicated single‐incision platform. However, case–control or prospective trials are warranted to draw more definitive conc lusions. Copyright © 2015 John Wiley & Sons, Ltd.
From S‐band mobile interactive multimedia to fixed satellite interactive multimedia: making satellite interactivity affordable at Ku‐band and Ka‐band
Authors: Arcidiacono A. , Finocchiaro D. , Collard F. , Scalise S. , Lazaro Blasco F. , De Gaudenzi R. , Cioni S. , Alagha N. , Andrenacci M. 
Published: November 2015

SummaryThis paper describes the evolution of the ETSI S‐band mobile interactive multimedia protocol to support fixed satellite interactive multimedia (F‐SIM) services exploiting existing Ku‐band and Ka‐band satellites. The key F‐SIM protocol differences for both physical and upper layers are described and justified. The F‐SIM protocol has been adopted by the recently deployed Eutelsat Broadcast Interactive System whose architecture, key system parameters, link budget examples and key composing elements are also described. Finally, a summary of laboratory and field trials results over the Eutelsat KA‐SAT multibeam satellite are illustrated. Copyright © 2015 John Wiley & Sons, Ltd.
Dysregulation of Wnt-Signaling and a Candidate Set of miRNAs Underlie the Effect of Metformin on Neural Crest Cell Development
Authors: Banerjee Poulomi , Dutta Sunit , Pal Rajarshi 
Published: November 2015

Abstract
Neural crest cells (NCC) are a population of epithelial cells that arise from the dorsal tube and undergo epithelial-mesenchymal transition (EMT) eventually generating tissues from peripheral nervous system, melanocytes, craniofacial cartilage, and bone. The antidiabetic drug metformin reportedly inhibits EMT in physiological conditions like cancer and fibrosis. We hypothesize that perturbation of EMT may also contribute to developmental disabilities associated with neural crest (NC) development. To understand the molecular network underlying metformin action during NC formation, we first differentiated murine embryonic stem (ES) cells into NCC and characterized them by demonstrating spatiotemporal regulation of key markers. Metformin treatment prompted a delay in delamination of NCC by inhibiting key markers like Sox-1, Sox-9, HNK-1, and p-75. We then revealed that metformin impedes Wnt axis, a major signaling pathway active during NC formation via DVL-3 inhibition and impairment in nuclear translocation of β-catenin. Concomitantly we identified and tested a candidate set of miRNAs that play a crucial role in NC cell fate determination. Further studies involving loss and gain of function confirmed that NCC specifiers like Sox-1 and Sox-9 are direct targets of miR-200 and miR-145, respectively and that they are essentially modulated by metformin. Our in vitro findings were strongly supported by in vivo studies in zebrafish. Given that metformin is a widely used drug, for the first time we demonstrate that it can induce a delayed onset of developmental EMT during NC formation by interfering with canonical Wnt signaling and mysregulation of miR-145 and miR-200.
Video Highlight: https://youtu.be/TZWqwMMIQ6k
Intelligent navigation to improve obstetrical sonography
Authors: Yeo Lami , Romero Roberto 
Published: November 2015

ABSTRACT‘Manual navigation’ by the operator is the standard method used to obtain information from two‐dimensional and volumetric sonography. Two‐dimensional sonography is highly operator dependent and requires extensive training and expertise to assess fetal anatomy properly. Most of the sonographic examination time is devoted to acquisition of images, while ‘retrieval’ and display of diagnostic planes occurs rapidly (essentially instantaneously). In contrast, volumetric sonography has a rapid acquisition phase, but the retrieval and display of relevant diagnostic planes is often time‐consuming, tedious and challenging. We propose the term ‘intelligent navigation’ to refer to a new method of interrogation of a volume dataset whereby identification and selection of key anatomical landmarks allow the system to: 1) generate a geometrical reconstruction of the organ of interest; and 2) automatically navigate, find, extract and display specific diagnostic planes. This is accomplished using operator‐independent algorithms that are both predictable and adaptive. Virtual Intelligent Sonographer Assistance (VIS‐Assistance®) is a tool that allows operator‐independent sonographic navigation and exploration of the surrounding structures in previously identified diagnostic planes. The advantage of intelligent (over manual) navigation in volumetric sonography is the short time required for both acquisition and retrieval and display of diagnostic planes. Intelligent navigation technology automatically realigns the volume, and reorients and standardizes the anatomical position, so that the fetus and the diagnostic planes are consistently displayed in the same manner each time, regardless of the fetal position or the initial orientation. Automatic labeling of anatomical structures, subject orientation and each of the diagnostic planes is also possible. Intelligent navigation technology can operate on conventional computers, and is not dependent on specific ultrasound platforms or on the use of software to perform manual navigation of volume datasets. Diagnostic planes and VIS‐Assistance videoclips can be transmitted by telemedicine so that expert consultants can evaluate the images to provide an opinion. The end result is a user‐friendly, simple, fast and consistent method of obtaining sonographic images with decreased operator dependency. Intelligent navigation is one approach to improve obstetrical sonography. Published 2015. This article is a U.S. Government work and is in the public domain in the USA.
Ester Modified Pyrrolidinium Based Ionic Liquids as Electrolyte Component Candidates in Rechargeable Lithium Batteries
Authors: Cao Xia , Röser Stephan , Rezaeirad Babak , He Xin , Streipert Benjamin , Winter Martin , Cekic‐Laskovic Isidora 
Published: November 2015

AbstractRoom temperature ionic liquids (RTILs), especially pyrrolidinium based RTILs with bis(trifluoromethane‐sulfonyl)imide (TFSI) as counterion, are frequently proposed as promising electrolyte component candidates thanks to their high thermal as well as high oxidation stability. In order to avoid a resource intensive experimental approach, mainly based on trial and error experiments, a computational screening method for pre‐selecting suitable candidate molecules was adopted and three homologous series compounds were synthesized by modifying the cation structure of pyrrolidinium RTILs. The obtained high purity RTILs: methyl‐methylcarboxymethyl pyrrolidinium TFSI (MMMPyrTFSI), methyl‐ethylcarboxymethyl pyrrolidinium TFSI (MEMPyrTFSI) and methylpropylcarboxymethyl pyrrolidinium TFSI (MPMPyrTFSI) revealed excellent thermal stabilities higher than 300 °C. Furthermore, MMMPyrTFSI and MPMPyrTFSI exhibit high oxidation stability up to 5.4 V vs. Li/Li+. No aluminum corrosion of current collector was observed at 5 V vs. Li/Li+. In addition to that, these RTILs display a superior salt (LiTFSI) solubility (3.0–3.5 M), compared to the unmodified RTIL 1‐butyl‐1‐methylpyrrolidinium TFSI (Pyr14TFSI) (1.5–2.0 M) at room temperature. All these properties make novel ester modified RTILs promising and interesting candidates for application in rechargeable lithium batteries.
Synthesis, Structures, and Magnetic Properties of Chiral One‐dimensional CrIII‐MnIIIHeterobimetallic Complexes Based on [(Tp)Cr(CN)3]–
Authors: Yao Min‐Xia , Deng Xiao‐Wei , Zhu Zhao‐Xia 
Published: November 2015

AbstractTwo CrIII‐MnIIIheterobimetallic compounds, [Mn((R,R)‐5‐MeOSalcy)Cr(Tp)(CN)3·2CH3CN]n(1‐RR) and [Mn((S,S)‐5‐MeOSalcy)Cr(Tp)(CN)3·2CH3CN]n(1‐SS) [Salcy =N,N′‐(1,2‐cyclohexanediylethylene)bis(salicylideneiminato) dianion], were synthesized by using the tricyanometalate building block, [(Tp)Cr(CN)3]–[Tp = tris(pyrazolyl) hydroborate] and chiral MnIIISchiff base precursors. Structural analyses and circular dichroism (CD) spectra revealed that1‐RRand1‐SSare a pair of enantiomers containing a neutral cyano‐bridged zigzag chain with (–Cr–C≡N–Mn–N≡C–)nas the repeating unit. Magnetic studies show that antiferromagnetic couplings between CrIIIand MnIIIions occur by cyanide bridges.1‐RRand1‐SSpresent metamagnetic, spin‐canting, and antiferromagnetic order behaviors at low temperatures.
Membrane versus centrifuge-based therapeutic plasma exchange: a randomized prospective crossover study
Authors: Hafer Carsten , Golla Paulina , Gericke Marion , Eden Gabriele , Beutel Gernot , Schmidt Julius J. , Schmidt Bernhard M. W. , De Reys Stef , Kielstein Jan T. 
Published: November 2015

Abstract

Background
Therapeutic plasma exchange (TPE) is either performed using a highly permeable filter with standard multifunctional renal replacement equipment (mTPE) or a centrifugation device (cTPE). Although both techniques are well established in clinical practice, performance of these two modes of TPE was never compared in a prospective randomized fashion. Thus we aimed to compare two commercially available therapeutic apheresis systems: mTPE (Octonova with Plasmaflo filter) and cTPE (Spectra Optia apheresis system).

Methods
Twenty-one patients (age 51.6 ± 13.5 years; 10 F/11 M; BMI 25.1 ± 5.0 kg/m2) were enrolled in this randomized, prospective, paired, crossover study performed in the Hannover Medical School, Germany. First treatment (either mTPE or cTPE) was chosen by an online randomization list. The primary endpoints were plasma removal efficiency with 1.2× of the total plasma volume exchanged. Secondary endpoints were total amount of plasma substances removed, such as IgG and fibrinogen. Further, the treatment effect on platelet count and complications were evaluated.

Results
Despite a comparable volume of the processed plasma, mTPE treatment time was 10.5 % longer than cTPE treatment time (p < 0.05), resulting in a 10 % lower plasma removal rate of the mTPE treatment. Both treatments were comparable in terms of decrease in median (IQR) IgG [pre-mTPE 5.34 (3.48–8.37), post-mTPE 1.96 (1.43–2.84) g/L; pre-cTPE 5.88 (3.42–8.84), post-cTPE 1.89 (1.21–3.52) g/L]. Also the median (IQR) amount of IgG removed in mTPE [13.14 (7.42–16.10) g] was not different from the cTPE treatment [9.30 (6.26–15.69) g]. This was also true for IgM removal. Platelet loss during mTPE was nearly twice as much as with cTPE (15 ± 9 versus 7 ± 9 %, p < 0.05).

Conclusion
Although the centrifugal procedures were conducted using flow rates that could easily be obtained using peripheral access, plasma removal efficiency was significantly higher and treatment time was significantly lower in cTPE as compared to mTPE. Despite this lower treatment time, the decline in markers of procedure efficacy was comparable. Especially in centers performing many procedures per year, cTPE in contrast to mTPE can reduce treatment time without compromising treatment efficacy.
Stop and ask for directions: factors affecting anuran detection and occupancy in Pampa farmland ponds
Authors: Moreira Leonardo F. B. , Moura Rafael G. , Maltchik Leonardo 
Published: November 2015

AbstractThere is a great need to understand the effects of man‐made land transformation on freshwater biodiversity, because agricultural landscapes provide habitat for many aquatic and semi‐aquatic organisms. However, not all forms of land use are equal in their capacity to support wildlife. Cattle grazing leads to a change in pasture vegetation structure, whereas conversion to commercial crop‐based agriculture promotes structural and chemical degradation of the ecosystem. From 2010 to 2012, in the Pampa biome, southern Brazil, we modelled anuran occupancy for 39 farmland ponds. Specifically, we determined detection probabilities associated with survey‐ and pond‐specific variables and examined tadpole occupancy in relation to land use in southern Brazil. We recorded eleven anuran species, but only five were detected at levels suitable for occupancy modelling. Species detectability varied with water temperature, extent of floating macrophyte cover, and sampling date. For three species, detection‐adjusted occupancy models indicated a relationship between occupancy and agricultural activities and/or livestock management. Agriculture areas negatively affected occupancy by Odontophrynus americanus and Physalaemus gracilis. The presence of livestock within a 500 m radius positively affected pond occupancy by Hypsiboas pulchellus. Other species were negatively associated with pond area or fish presence. Our results demonstrate that traditional extensive livestock farming can provide a buffer that protects freshwater environments, because it did not greatly modify the grassland matrix. We argue that further species‐based approaches will be critical for developing effective conservation strategies for anurans, particularly in the context of the expanding rice production/exotic forests in southern Brazil.
Reflectance and artificial nest experiments of reptile and bird eggs imply an adaptation of bird eggs against ultraviolet
Authors: Wang Jichao , Yang Canchao , Shi Haitao , Liang Wei 
Published: November 2015

AbstractInterspecific comparative studies in trait responses to nest predation will help uncover potential costs associated with changes in nest predation risk that may constrain the degree of the response. Reptiles build large mounds of sand, soil or compost in which they bury and leave their eggs after laying. As their eggs are not exposed, reptiles consistently lay immaculate white eggs; while some birds that also lay immaculate white eggs place their nests in exposed sites under sunlight. Comparing the spectrum of reptile and bird eggs, especially in the ultraviolet (UV) region, may help us understand the evolution of coloration in bird eggs. We measured white immaculate eggs from four species of turtle and three species of birds by spectrometer, and compared their hue, chroma, UV brightness, and total brightness. Our results indicated that the UV reflectance of bird eggs consistently exhibited peaks and troughs in waveform that obviously differed from that of turtle eggs, which rising gradually from 300 to 400 nm. This finding implies that bird eggs have been released from enclosed nests, like those of reptiles, and have thus evolved an adaptation in UV reflectance as a signal. Furthermore, artificial nest experiments indicated that predation rates of bird eggs were significantly higher than those of turtle eggs, implying that such a signal might exist. Our study provides baseline data and perspective for further research on the evolution of egg coloration between reptiles and birds.
Looking at the dark and bright sides of identity formation: New insights from adolescents and emerging adults in Japan
Authors: Hatano Kai , Sugimura Kazumi , Crocetti Elisabetta 
Published: November 2015

ABSTRACTThe aim of the present study was to gain new insights into the dark and bright sides of identity formation with a sample of 1851 Japanese adolescents and emerging adults, applying a three‐dimensional model of identity formation (i.e., commitment, in‐depth exploration, and reconsideration of commitment). By means of cluster analysis, we identified five statuses that strongly resembled statues extracted in prior research with Western youth: achievement, foreclosure, moratorium, diffusion, and searching moratorium. We found that each status reported a distinct profile in terms of personality and psychosocial problems. Importantly, we found that the searching moratorium status was adaptive in adolescence but not in emerging adulthood. These results suggest that the five statuses are replicable in Japanese adolescents and emerging adults, and that the searching moratorium status presents a combination of the bright and dark sides whose prevalence varies with age. Clinical implications for identity research and intervention programs are discussed.
Risk of dementia and death in the long‐term follow‐up of the Pittsburgh Cardiovascular Health Study–Cognition Study
Authors: Kuller Lewis H. , Lopez Oscar L. , Becker James T. , Chang Yuefang , Newman Anne B. 
Published: November 2015

AbstractIntroductionIncreasing life expectancy has resulted in a larger population of older individuals at risk of dementia.MethodsThe Cardiovascular Health Study–Cognition Study followed 532 participants from 1998–99 (mean age 79) to 2013 (mean age 93) for death and dementia.ResultsRisk of death was determined by extent of coronary artery calcium, high‐sensitivity cardiac troponin, brain natriuretic peptide, and white matter grade. Significant predictors of dementia were age, apolipoprotein‐E4, vocabulary raw score, hippocampal volume, ventricular size, cognitive performance, and number of blocks walked. By 2013, 160 of 532 were alive, including 19 cognitively normal. Those with normal cognition had higher grade education, better cognition test scores, greater hippocampal volume, faster gait speed, and number of blocks walked as compared with survivors who were demented.DiscussionFew survived free of dementia and disability. Prevention and delay of cognitive decline for this older population is an imperative.
Patterns of individual coping, engagement with social supports and use of formal services among a five-country sample of resilient youth
Authors: Ungar M. , Theron L. , Liebenberg L. , Tian Guo-Xiu , Restrepo A. , Sanders J. , Munford R. , Russell S. 
Published: November 2015

Background.Although resilience among victims of child abuse is commonly understood as a process of interaction between individuals and their environments, there have been very few studies of how children's individual coping strategies, social supports and formal services combine to promote well-being.Method.For this study, we conducted a multi-phase analysis of a qualitative dataset of 608 interviews with young people from five countries using grounded theory strategies to build a substantive theory of young people's service and support use patterns. We started with an analysis of ten interviews (two from each country) and then compared these findings to patterns found in each country's full dataset.Results.The substantive theory that emerged explains young people's transience between individual coping strategies (cognitive and behavioral), reliance on social supports (family members, peers and teachers), and engagement with formal service providers whose roles are to provide interventions and case management. Young people's patterns of navigation were shown to be contingent upon the individual's risk exposure, his or her individual capacity to cope, and the quality of the formal and informal supports and services that are available and accessible.Conclusion.Differing amounts of formal resources in low-, middle- and high-income countries influence patterns of service use. Implications for better coordination between formal mental health services and social supports are discussed.
Consequences of viscous anisotropy in a deforming, two-phase aggregate. Why is porosity-band angle lowered by viscous anisotropy?
Authors: Takei Yasuko , Katz Richard F. 
Published: November 2015

In laboratory experiments that impose shear deformation on partially molten aggregates of initially uniform porosity, melt segregates into high-porosity sheets (bands in cross-section). The bands emerge at $15^{\circ }$–$20^{\circ }$ to the shear plane. A model of viscous anisotropy can explain these low angles whereas previous simpler models have failed to do so. The anisotropic model is complex, however, and the reason that it produces low-angle bands has not been understood. Here we show that there are two mechanisms: (i) suppression of the well-known tensile instability, and (ii) creation of a new shear-driven instability. We elucidate these mechanisms using linearised stability analysis in a coordinate system that is aligned with the perturbations. We consider the general case of anisotropy that varies dynamically with deviatoric stress, but approach it by first considering uniform anisotropy that is imposed a priori and showing the difference between static and dynamic cases. We extend the model of viscous anisotropy to include a strengthening in the direction of maximum compressive stress. Our results support the hypothesis that viscous anisotropy is the cause of low band angles in experiments.