bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nonprofits and community resilience during a pandemic: a France-Quebec perspective
Authors: Lethielleux Laëtitia , Demeyère Caroline , Artis Amélie , Vézina Martine , Girard Jean-Pierre 
Published: July 2024

PurposeThis article examines the links between nonprofits and communities’ resilience during the COVID-19 crisis. Previous research on resilience has overlooked nonprofits, with limited studies on their ongoing resilience processes. While nonprofits’ potential to lead their communities’ resilience has been highlighted, we know little about how this potential can be fully achieved.Design/methodology/approachNonprofit’s potential to lead their communities’ resilience has been highlighted. Yet, nonprofits are also deeply affected by crises, and little is known about their organizational resilience. This study explores the interplay between nonprofits’ organizational resilience and community resilience in the face of crises. We draw from an international comparative case study based on two participatory research designs in France and Quebec during the Covid-19 crisis.FindingsThe results highlight similarities and differences in how nonprofits’ developed organizational resilience capabilities. These different organizational resilience processes affected in return the reactive and proactive roles the nonprofits could play in community resilience.Research limitations/implicationsLimitations of the research method include its time boundaries, the specificity of the Covid-19 crisis, which differs from natural hazards which are traditionally studied in the resilience literature (e.g.: Roberts et al., 2021). The unicity of the cases fits the comprehensive purpose of the study, and generalizations of the results are limited.Practical implicationsEmpirically, we offer an original approach of nonprofits and community resilience as ongoing interdependent processes.Originality/valueThe article contributes to the organizational resilience literature in refining how nonprofits’ characteristics and embeddedness in their community affect their development of resilience capabilities. We theorize the dynamic reciprocal links between nonprofits and community resilience.
When deliberative mini‐publics’ outcomes and political decisions clash: Examining how responsive communication influences legitimacy perceptions
Authors: GOOVAERTS INE , DE FINE LICHT JENNY , MARIEN SOFIE 
Published: July 2024

AbstractThis article explores how citizens’ legitimacy perceptions are affected when decision makers deviate from the recommendations of a deliberative mini‐public (DMP), and what can be done to mitigate negative consequences. The results of a preregistered vignette experiment in Belgium (N = 2659) support our two main expectations. First, citizens’ legitimacy perceptions decrease when politicians do not follow the outcome of a DMP. Second, when politicians communicate responsively about this – meaning that they show respect for the recommendations and publicly justify why they deviated from them – legitimacy perceptions substantially increase, generally reaching the level of those cases where recommendations are followed. Diving deeper into this result also shows that for this effect to occur, citizens must find the provided reasoning valid and acceptable. Finally, the results hold among both policy winners and policy losers. These findings have implications for the literature on democratic innovations, empirical legitimacy, and political representation, but also for policymakers striving to combine arrangements of public participation that go beyond triviality, with political responsibility for the whole, and sustained mechanisms for accountability.
An Indeterminate Conception of Practical Reasoning
Authors: Dannenberg Jorah 
Published: July 2024

AbstractThis paper makes a case for treating the boundary between what counts as practical reasoning and what does not as essentially indeterminate. The idea that there is an “essential indeterminacy in what can be counted as a rational deliberative process” was put forward by Bernard Williams in his well‐known discussion of statements about an agent's reasons for action. But in contrast to the more familiar argument of that paper, the idea has received almost no attention. To understand and defend the idea, I first offer a somewhat novel reconstruction of the more familiar argument against making statements about a person's reasons intended on an “external” interpretation. On my reading, the argument shows how making such statements runs afoul of ideals of honesty in our interpersonal dealings. I then argue for countenancing an essential indeterminacy in what counts as practical reasoning, in a manner that involves a re‐application of these same ideals of honesty, albeit at a higher level of abstraction. One advantage of understanding the entire discussion of reasons statements and reasoning along these lines is that it highlights the deeply anti‐rationalistic flavor of Williams' own interest in these topics. Unsurprisingly, Williams' treatment displays a deep affinity with the anti‐rationalistic ethics advanced by Hume. It also turns out to be at cross purposes with the far more rationalistic ethical vision that animates more recent attempts to advance a “Humean Theory of Reasons,” which is sometimes mistakenly seen as following in Williams' and Hume's footsteps.
Anscombe on the shallowness of consequentialism
Authors: Taylor Craig 
Published: July 2024

AbstractThis paper is divided into two parts. In the first I outline and defend Elizabeth Anscombe's claim that consequentialism is a shallow philosophy by considering how two contemporary consequentialists reach opposing but equally outlandish moral conclusions on a matter as fundamental as whether it is good or bad that the human race continues. In the second I argue that in order to show what is wrong with the consequentialist arguments presented in part one, we need to deploy a wider range of critical resources than what typically appears in contemporary analytic moral philosophy. One example of a relevant and under‐appreciated resource I then consider is satire as a mode of moral thought.
Tooth autotransplantation and resin composite reshaping as a multidisciplinary approach for treating dental agenesia: A 10‐year follow‐up
Authors: Ferraresso Lucas Fernando de Oliveira Tomáz , Besegato João Felipe , Maler Gustavo Lopes , Takahashi Ricardo , Stábile Glaykon Alex Vitti , Hoeppner Márcio Grama 
Published: July 2024

AbstractCase reportThis case report describes the multidisciplinary approach performed in a 9‐year‐old male patient with dental agenesia affecting teeth 21 and 22. Autotransplantation of the right upper second premolar with incomplete rhizogenesis to the missing area was combined with coronary reshaping with resin composite and orthodontic therapy. The treatment began with the extraction of the deciduous upper left central incisor, bone preparation for the recipient site of the donor tooth, atraumatic extraction of the right upper second premolar and immediate autotransplantation in the surgically prepared recipient site. Subsequently, sutures to reposition the flap and a rigid splint were performed. After 12 months, coronary reshaping of the autotransplanted tooth with resin composite was carried out. Orthodontic treatment involving the use of a fixed appliance was used to correct the interdental spaces and achieve adequate occlusion. Clinical and radiographic follow‐up 10 years after tooth autotransplantation and 9 years after reshaping revealed partial obliteration of the pulp chamber, root resorption, ankylosis and the presence of endodontic treatment.ConclusionsThe long‐term outcomes highlighted that tooth autotransplantation represents a biologically and cost‐effective procedure for replacing missing teeth in young patients, particularly in cases of incomplete rhizogenesis of the autotransplanted tooth.Clinical SignificanceThis case report discusses tooth autotransplantation and resin composite reshaping as viable and long‐term clinical options for treating young patients with dental agenesis.
Multi‐omics analysis to evaluate the effects of solar exposure and a broad‐spectrum SPF50+ sunscreen on markers of skin barrier function in a skin ecosystem model
Authors: Jacques Carine , Jamin Emilien L. , Noustens Anais , Lauze Christophe , Jouanin Isabelle , Doat Gautier , Debrauwer Laurent , Bessou‐Touya Sandrine , Stockfleth Eggert , Duplan Hélène 
Published: July 2024

AbstractSun exposure induces major skin alterations, but its effects on skin metabolites and lipids remain largely unknown. Using an original reconstructed human epidermis (RHE) model colonized with human microbiota and supplemented with human sebum, we previously showed that a single dose of simulated solar radiation (SSR) significantly impacted the skin metabolome and microbiota. In this article, we further analyzed SSR‐induced changes on skin metabolites and lipids in the same RHE model. Among the significantly altered metabolites (log2‐fold changes with p ≤ 0.05), we found several natural moisturizing factors (NMFs): amino acids, lactate, glycerol, urocanic acid, pyrrolidone carboxylic acid and derivatives. Analyses of the stratum corneum lipids also showed that SSR induced lower levels of free fatty acids and higher levels of ceramides, cholesterols and its derivatives. An imbalance in NMFs and ceramides combined to an increase of proinflammatory lipids may participate in skin permeability barrier impairment, dehydration and inflammatory reaction to the sun. Our skin model also allowed the evaluation of an innovative ultraviolet/blue light (UV/BL) broad‐spectrum sunscreen with a high sun protection factor (SPF50+). We found that using this sunscreen prior to SSR exposure could in part prevent SSR‐induced alterations in NMFs and lipids in the skin ecosystem RHE model.
The protective effect of 1400W against ischaemia and reperfusion injury is countered by transient medullary kidney endothelial dysregulation
Authors: Pasten Consuelo , Lozano Mauricio , Osorio Luis A. , Cisterna Matías , Jara Valeria , Sepúlveda Catalina , Ramírez‐Balaguera Daniela , Moreno‐Hidalgo Viviana , Arévalo‐Gil Dayana , Soto Paola , Hurtado Valeria , Morales Antonia , Méndez Gonzalo P. , Busso Dolores , Leon Pablo , Michea Luis , Corvalán Daniela , Luarte Alejandro , Irarrazabal Carlos E. 
Published: July 2024

AbstractRenal ischaemia and reperfusion (I/R) is caused by a sudden temporary impairment of the blood flow. I/R is a prevalent cause of acute kidney injury. As nitric oxide generated by inducible nitric oxide synthase (iNOS) has detrimental effects during I/R, the pharmacological blockade of iNOS has been proposed as a potential strategy to prevent I/R injury. The aim of this study was to improve the understanding of 1400W (an iNOS inhibitor) on renal I/R as a pharmacological strategy against kidney disease. BALB/c mice received 30 min of bilateral ischaemia, followed by 48 h or 28 days of reperfusion. Vehicle or 1400W (10 mg/kg) was administered 30 min before inducing ischaemia. We found that after 48 h of reperfusion 1400W decreased the serum creatinine, blood urea nitrogen, neutrophil gelatinase‐associated lipocalin and proliferating cell nuclear antigen 3 in the I/R animals. Unexpectedly, we observed mRNA upregulation of genes involved in kidney injury, cell‐cycle arrest, inflammation, mesenchymal transition and endothelial activation in the renal medulla of sham animals treated with 1400W. We also explored if 1400W promoted chronic kidney dysfunction 28 days after I/R and did not find significant alterations in renal function, fibrosis, blood pressure or mortality. The results provide evidence that 1400W may have adverse effects in the renal medulla. Importantly, our data point to 1400W‐induced endothelial dysfunction, establishing therapeutic limitations for its use.
imageKey points
Acute kidney injury is a global health problem associated with high morbidity and mortality.
The pharmacological blockade of inducible nitric oxide synthase (iNOS) has been proposed as a potential strategy to prevent AKI induced by ischaemia and reperfusion (I/R).
Our main finding is that 1400W, a selective and irreversible iNOS inhibitor with low toxicity that is proposed as a therapeutic strategy to prevent kidney I/R injury, produces aberrant gene expression in the medulla associated to tissue injury, cell cycle arrest, inflammation, mesenchymal transition and endothelial activation.
The negative effect of 1400W observed in the renal medulla at 48 h from drug administration, is transient as it did not translate into a chronic kidney disease condition.
Evaluation and management of hypertensive emergency
Authors: Miller Joseph B , Hrabec Daniel , Krishnamoorthy Vijay , Kinni Harish , Brook Robert D 
Published: July 2024

Abstract
Hypertensive emergencies cause substantial morbidity and mortality, particularly when acute organ injury is present. Careful and effective strategies to reduce blood pressure and diminish the effects of pressure-mediated injury are essential. While the selection of specific antihypertensive medications varies little across different forms of hypertensive emergencies, the intensity of blood pressure reduction to the target pressure differs substantially. Treatment hinges on balancing the positive effects of lowering blood pressure with the potential for negative effects of organ hypoperfusion in patients with altered autoregulatory mechanisms. When patients do not have acute organ injury in addition to severe hypertension, they benefit from a conservative, outpatient approach to blood pressure management. In all cases, long term control of blood pressure is paramount to prevent recurrent hypertensive emergencies and improve overall prognosis. This review discusses the current evidence and guidelines on the evaluation and management of hypertensive emergency.
Microscopic and submicroscopic exploration of diplolepideae peristome structures in hygroscopic movement
Authors: Wu Yanzhi , Wu Qimei , Zhang Zhaohui , Wang Zhihui 
Published: July 2024

Abstract
Background
The Diplolepideae are the larger group within the Arthrodontae mosses, characterized by peristomes formed from residual cell walls. It is now understood that these peristomes exhibit diverse hygroscopic movements, playing a crucial role in spore release. However, the exact mechanism behind this movement remains unclear, lacking direct evidence. This study investigated the microscopic and submicroscopic structures of the peristomes in three Diplolepideae species: Hypopterygium fauriei (Besch.), Pylaisia levieri (Müll. Hal.) Arikawa and Regmatodon declinatus (Hook.) Brid. Scanning electron microscopy (SEM) and transmission electron microscopy (TEM) were used to reveal the differences in their hygroscopic movement mechanisms.

Results
The three species exhibited distinct responses upon wetting: H. fauriei’s exostome closed inwards, P. levieri’ opened outwards, and R. declinatus’ elongated significantly. These differences are attributed to the varying microfibril deposition in the exostome layers. Uniform deposition in the inner layer and minimal deposition in the outer layer enabled exostome opening upon wetting and closing when dry. Our findings suggest that the diastole and contraction of fine microfibrils in the exostome plates and ridges are the key drivers of hygroscopic movement.

Conclusions
This study provides further evidence at both the structural and submicroscopic levels, contributing to the unraveling of the hygroscopic movement mechanism in Diplolepideae peristomes. This enhanced understanding sheds light on the relationship between peristome structure and function.
Dexmedetomidine administration as a possible cognitive enhancer through increasing the level of brain-derived neurotrophic factors in surgical patients: a systematic review and meta-analysis
Authors: Dehbozorgi Masoud , Fereidooni Fatemeh , Bozorgmehr Ramin , Bagherpour Javad Zebarjadi , Shafiee Arman , Mohammadi Ida , Amini Mohammad Javad , Seighali Niloofar , Jafarabady Kyana , Rajai Firouzabadi Shahryar , Akbarzade Diba , Bahri Razman Arabzadeh 
Published: July 2024

Abstract
Objective
This meta-analysis aimed to investigate the effect of dexmedetomidine on brain-derived neurotrophic factor (BDNF) levels in individuals undergoing various medical procedures. We systematically searched electronic databases and manually identified relevant articles to assess the impact of dexmedetomidine on BDNF levels in surgical patients.

Methods
A comprehensive literature search was conducted in PubMed, Scopus, Embase, and Web of Science databases with no language restrictions. Studies that examined the effects of dexmedetomidine administration on BDNF levels in surgical patients were included.

Results
The overall analysis revealed a statistically significant increase in BDNF levels in individuals receiving dexmedetomidine compared to controls (Standardized Mean Difference SMD = 1.65, 95% CI: 1.02 to 2.28; I2: 89%). Subgroup analyses based on the anesthesia method (p < 0.01), and the type of surgery (p < 0.01) showed significant between-group differences (Fig. 3). The results of the sensitivity analyses indicated that individual studies did not significantly affect the overall results.

Conclusion
This meta-analysis indicates that dexmedetomidine administration is associated with a significant increase in BDNF levels in individuals undergoing surgical procedures. These findings highlight the potential role of dexmedetomidine in modulating BDNF levels, which may have implications for optimizing perioperative neuroprotective strategies and improving patient outcomes.
Implementation and adoption of SOAP-M and SBAR at a German anesthesiology department – a single-center survey study
Authors: Keil Oliver , Wegener Justus Bernd , Schiller Benjamin , Vetter Mathäus , Flentje Markus , Eismann Hendrik 
Published: July 2024

Abstract
Background
Checklists are a common tool used in order to mitigate risks caused by human factors and can facilitate the safe induction of anesthesia as well as handovers. SBAR (Situation, Background, Assessment, Recommendation) is a checklist recommended by the WHO and DGAI for handovers, while SOAP-M (Suction, Oxygen, Airway, Pharmaceuticals, Monitoring) is a checklist for the induction of anesthesia. This study investigates the implementation and adoption of these two checklists.

Methods
We conducted a single-center online survey one year after the implementation of SOAP-M and SBAR at a university hospital’s anesthesiology department, using scales from three validated questionnaires to assess safety attitudes as well as the behavior of staff and the perceived usefulness of the checklists.

Results
Staff with a high score in general attitude towards patient safety, as determined by the safety attitudes questionnaire, considered both checklists useful additions to their work environment. Nurses and physicians (p = 0.102) as well as groups divided according to work experience (p = 0.077) showed no significant differences in using SOAP-M and SBAR. Perceived usefulness was significantly higher (p < 0.001) among users of the checklists, and the same goes for positive reinforcement (p < 0.001), social cues (p = 0.0215) and goal cues (p = 0.0252).

Conclusion
SOAP-M and SBAR are perceived as useful checklists for patient handovers and anesthesia induction by tertiary referral hospital’s employees with high score in general safety attitude and were therefore commonly used one year after their introduction. No significant difference in checklist adoption between occupations as well as groups divided according to work experience could be found. Perceived usefulness is significantly higher among users of the checklist, who feel using the checklists provides more support.
Association between dietary inflammatory index and energy-adjusted dietary inflammatory index and constipation in US adults
Authors: Zhao Xuelian , Wang Xiaoyu , Quan Longfang 
Published: July 2024

Abstract
Background
Diet and inflammation are associated with constipation. Dietary inflammation index (DII) and energy-dietary inflammation index (E-DII) have not been evaluated together with constipation. Therefore, this study was conducted to further observe the relationship between DII and E-DII and constipation in American adults.

Methods
Data were extracted from the National Health and Nutrition Examination Survey (NHANES) for 12,400 adults aged 20 years and older between 2005 and 2010. DII and E-DII were obtained by employing data from the two 24-h dietary recall of the participants. Constipation was defined and categorized using the Bristol Stool Form Scale.

Results
In the logistic regression model, the relationship between DII and E-DII and constipation remained positive after adjusting for confounding factors (odds ratio [OR] = 1.13; 95% confidence interval [CI]: 1.07–1.20 in DII logistic regression model III; odds ratio [OR] = 1.09; 95% confidence interval [CI]: 1.03–1.17 in E-DII logistic regression model III). Constipation was more common in quartile 4 (DII: 2.87—5.09; E-DII: 1.78—8.95) than in quartile 1 (DII: -5.11—0.25; E-DII: -2.60—0.11) (OR = 1.79, 95% CI: 1.30–2.47 in DII and OR = 1.75, 95% CI: 1.25–2.46 in E-DII for all participants; OR = 2.04, 95% CI: 1.39–3.00 in DII OR = 2.20, 95% CI: 1.39–3.47 in E-DII for males; OR = 1.86, 95% CI: 1.08–3.22 and OR = 1.80, 95% CI: 1.06–3.06 for females). These results were confirmed using multiple imputations.

Conclusions
The findings of this study show that a high DII and E-DII were associated with an increased incidence of constipation among US adults.