bluuebunny/crossref_metadata_2025_split huggingface dataset:
On the Impact and Benefits of AMDAR Observations in Operational Forecasting—Part I: A Review of the Impact of Automated Aircraft Wind and Temperature Reports
Authors: Petersen Ralph Alvin 
Published: July 2015

Abstract
This paper reviews the impact of World Meteorological Organization (WMO) Aircraft Meteorological Data Relay (AMDAR) observations on operational numerical weather prediction (NWP) forecasts at both regional and global scales that support national and local weather forecast offices across the globe. Over the past three decades, data collected from commercial aircraft have helped reduce flight-level wind and temperature forecast errors by nearly 50%. Improvements are largest in 3–48-h forecasts and in regions where the automated reports 1) are most numerous, 2) cover a broad area, and 3) are available at multiple levels (e.g., made during aircraft ascent and descent). Improvements in weather forecasts due to these data have already had major impacts on a variety of aspects of airline operations, ranging from fuel savings from improved wind and temperature forecasts used in flight planning to passenger comfort and safety due to better awareness of en route and near-terminal weather hazards. Aircraft wind and temperature observations now constitute the third most important dataset for global NWP and, in areas of ample reports, have become the single most important dataset for use in shorter-term, regional NWP applications. Automated aircraft reports provide the most cost-effective data source for improving NWP, being more than 5 times more cost effective than any other major-impact observing system. They also present an economical alternative for obtaining tropospheric profiles both in areas of diminishing conventional observation and as a supplement to existing datasets, both in time and space. An evaluation of moisture observations becoming available from an increasing number of AMDAR-equipped aircraft will be presented in Part II of this paper, including examples of the use of the full array of AMDAR observations in a variety of forecasting situations.
The Madden–Julian Oscillation’s Influence on Spring Rainy Season Precipitation over Equatorial West Africa*
Authors: Berhane Fisseha , Zaitchik Benjamin , Badr Hamada S. 
Published: July 2015

Abstract
This paper characterizes the influence of the Madden–Julian oscillation (MJO) on spring rainy season (March–June) convection variability over equatorial West Africa (EWA) and investigates mechanisms of association. It is found that the MJO has a significant impact on convection and precipitation anomalies over the region. Over large portions of EWA, MJO impacts on rainfall constitute a difference on the order of 20%–50% from average daily rain rates for the season. This impact is primarily due to the direct influence of the eastward movement of the MJO convective core into EWA, which is associated with westerly low-level wind anomalies that advect moisture from the Atlantic Ocean to the region. In addition, equatorial Rossby and Kelvin waves triggered by MJO convection anomalies over the Indian Ocean have a significant and systematic influence on EWA spring rainy season precipitation. The Kelvin wave contribution and the relative strength of the direct MJO convective influence compared to that of equatorial wave activity differs from findings of studies that have examined MJO influence on EWA during boreal summer. In addition, MJO is found to influence precipitation extremes during spring rains in a manner that is not observed in summer. Importantly, in this analysis the influences of MJO convection and each of the MJO-associated convectively coupled equatorial waves frequently coincide, reaching EWA approximately 20 days after MJO convection initiates in the Indian Ocean. This coincident timing enhances the total MJO impact on the region, and it also implies that MJO events have potential for prediction of regional-scale convection and rainfall anomalies over EWA in this season.
The Forcing of Monthly Precipitation Variability over Southwest Asia during the Boreal Cold Season
Authors: Hoell Andrew , Shukla Shraddhanand , Barlow Mathew , Cannon Forest , Kelley Colin , Funk Chris 
Published: July 2015

Abstract
Southwest Asia, defined as the region containing the countries of Afghanistan, Iran, Iraq, and Pakistan, is water scarce and receives nearly 75% of its annual rainfall during the boreal cold season of November–April. The forcing of southwest Asia precipitation has been previously examined for the entire boreal cold season from the perspective of climate variability originating over the Atlantic and tropical Indo-Pacific Oceans. This study examines the intermonthly differences in precipitation variability over southwest Asia and the atmospheric conditions directly responsible in forcing monthly November–April precipitation.
Seasonally averaged November–April precipitation over southwest Asia is significantly correlated with sea surface temperature (SST) patterns consistent with Pacific decadal variability (PDV), El Niño–Southern Oscillation (ENSO), and the long-term change of global SST (LT). In contrast, the precipitation variability during the individual months of November–April is unrelated and is correlated with SST signatures that include PDV, ENSO, and LT in different combinations.
Despite strong intermonthly differences in precipitation variability during November–April over southwest Asia, similar atmospheric circulations, highlighted by a stationary equivalent barotropic Rossby wave centered over Iraq, force the monthly spatial distributions of precipitation. Tropospheric flow on the eastern side of the equivalent barotropic Rossby wave modifies the flux of moisture and advects the mean meridional temperature gradient, resulting in temperature advection that is balanced by vertical motions over southwest Asia. The forcing of monthly southwest Asia precipitation by equivalent barotropic Rossby waves is different from the forcing by baroclinic Rossby waves associated with tropically forced–only modes of climate variability.
Sensitivities in Large-Eddy Simulations of Mixed-Phase Arctic Stratocumulus Clouds Using a Simple Microphysics Approach*
Authors: Kaul Colleen M. , Teixeira João , Suzuki Kentaroh 
Published: July 2015

Abstract
Arctic mixed-phase stratocumulus clouds are maintained by feedbacks between microphysical and dynamical phenomena, but the details of these interactions are incompletely understood. Although large-eddy simulations are a promising means of elucidating microphysics–turbulence relationships, the use of sophisticated microphysical schemes complicates analysis of their results. Here, the ability of a simplified one-moment scheme to capture basic features of this cloud type is investigated through simulations based on Mixed-Phase Arctic Cloud Experiment (MPACE), SHEBA/FIRE-ACE, and Indirect and Semi-Direct Aerosol Campaign (ISDAC) intercomparison studies. The results of the simple scheme show reasonable agreement with liquid and ice water path predictions reported by models using schemes of similar or greater complexity. Additional tests are performed to evaluate the sensitivity of the results to three main parameters of the scheme: the snow and ice size distribution intercept parameters and the exponent appearing in the temperature-dependent phase-partition function, which is used to diagnose cloud condensate amounts. Sensitivities of the SHEBA and ISDAC cases, both of which have low surface heat fluxes and low precipitation rates, tend to be similar, while the MPACE case, with higher surface fluxes and precipitation rates, shows somewhat different trends. Results of all three cases are found to be sensitive to the snow size distribution intercept parameter, but this quantity can be adequately estimated using a recently developed diagnostic expression based on observations of Arctic clouds.
Renal Disease Risk Factors Among Risk Groups Comprised of African American Women With Type 2 Diabetes
Authors: Migliore Casey L. , Vorderstrasse Allison , Pan Wei , Melkus Gail D’Eramo 
Published: July 2015

Purpose The purpose of this study was to explore and describe the prevalence of renal disease risk factors and the categorization of renal disease risk groups among African American women with type 2 diabetes mellitus (T2DM) who participated in a self-management and coping skills training intervention. We also explored and described the change in renal disease risk factors within and between risk groups, determining if participation in a culturally relevant coping skills training intervention decreased renal disease risk. Methods This study was a secondary analysis of data from a longitudinal intervention study and included all 109 African American women with T2DM from the primary intervention study. This study examined the prevalence of 4 renal disease risk factors among the women at baseline via descriptive statistics, used cluster analysis to divide the women into risk groups and categorize the risk groups, and also measured the change in risk factors over time among risk groups via mixed modeling. Results A majority of the women had a hemoglobin A1C ≥7% (62.39%) and were obese (75.93%). The high-risk cluster displayed clinically significant declines in mean systolic blood pressure, triglycerides, and A1C in both the control and intervention groups, and the intervention was more effective in reducing triglycerides and A1C levels among high-risk participants than low-risk. Overall, the control, high-risk group exhibited the largest declines in systolic blood pressure, triglycerides, and A1C. Conclusions This study displays the importance of acknowledging African American women with type 2 diabetes mellitus (T2DM) at high risk for renal disease in health care settings, which is often overlooked, and realizing that renal disease risk reduction is obtainable.
Local Powers and Judicial Constraints in a Case of Rape in India
Authors: Berti Daniela 
Published: July 2015

AbstractSince independence, the Indian State has shown a voluntarist approach in the judicial domain. This has led to the introduction of severe laws against customary relations of exploitation, harassment, and discrimination that rest on caste, gender, or religious differences. While this policy has enhanced a deeper legal culture, and provoked a new legal activism within the Indian population, it has not extirpated the local relations of dominance and exploitation. This paper provides an ethnographic account of how the rape of a young girl from a lower caste in Himachal Pradesh (Northern India) was dealt with in the judicial domain. It will thus provide an analysis of the interplay between traditional power relations and new forces that oppose those power relations through the rule of law. It will show how this interplay is visible in trial, and how it interferes with criminal procedures followed by the court.
Prevalence of Metatarsus Adductus in Symptomatic Hallux Valgus and Its Influence on Functional Outcome
Authors: Loh Bryan , Chen Jerry Yongqiang , Yew Andy Khye Soon , Chong Hwei Chi , Yeo Malcolm Guan Hin , Tao Peng , Koo Kevin , Rikhraj Singh Inderjeet 
Published: July 2015

Background: Metatarsus adductus (MA) increases the risk of developing symptomatic hallux valgus (HV). This study aimed to determine the prevalence of MA in patients with symptomatic HV and to evaluate how it affected the functional outcome after scarf osteotomy. Methods: Between January 2007 and June 2012, a total of 206 patients who underwent scarf osteotomy for symptomatic HV at a tertiary hospital were included. The metatarsus adductus angle (MAA) was determined using the Modified Sgarlato method, and these patients were categorized into 2 groups: MA (MAA > 20 degrees); and Control (MAA ≤ 20 degrees). The patients were prospectively followed for 2 years. Results: The prevalence of MA was 33% (68/206) with a mean MAA of 24 ± 4 degrees (range = 20-39). There was a 21 ± 12 degrees and 18 ± 9 degrees improvement in hallux valgus angle for the MA and Control groups, respectively ( P = .061), whereas there was a 6 ± 4 degrees and 6 ± 3 degrees improvement in intermetartarsal angle for the MA and Control groups, respectively ( P = .475). The visual analog scale, AOFAS Hallux Metatarsophalangeal-Interphalangeal Scale, and Physical and Mental Component Scores were comparable between the 2 groups both preoperatively and at 2 years’ follow-up (all P > .05). Two patients in the control group required revision surgery for recurrence symptomatic HV. Conclusion: The authors conclude that MA did not predispose the patient to poorer functional outcome after scarf osteotomy with the advent of good operative techniques. Level of Evidence: Level II, prospective comparative study.
Contribution of the cerebellum to cognitive performance in children and adolescents with multiple sclerosis
Authors: Weier Katrin , Till Christine , Fonov Vladimir , Yeh E Ann , Arnold Douglas L , Banwell Brenda , Collins D Louis 
Published: July 2015

Background: Posterior fossa lesions are common in pediatric-onset multiple sclerosis (MS), which is of concern, given the known role of the cerebellum in cognition. Objectives: To investigate the relationship between cerebellar pathology and cognitive function in youth with pediatric-onset MS. Methods: Twenty-eight pediatric-onset relapsing–remitting MS patients (21 girls; mean age 16.2 years; mean disease duration 4.3 years, median Expanded Disability Status Scale 1.25) were compared to 33 age- and sex-matched healthy controls. Participants underwent structural magnetic resonance imaging (MRI) and neuropsychological evaluation to assess intelligence, attention, processing speed, language, visuo-motor integration, and fine-motor dexterity. Associations between cognitive outcomes and cerebellar volume independent of cerebral volume were examined. Results: Cognitive and motor performance of the MS group was reduced relative to controls (all p<0.003). While cerebellar volumes did not differ between groups, cerebellar posterior lobe volume and infratentorial lesion volume accounted for extra variance on measures of information processing ( R2=0.43; p=0.02) and vocabulary ( R2=0.56; p=0.04) in patients (controlling for cerebral volume and sex), but not in controls. Conclusion: Smaller cerebellar posterior lobe volume, a known region for cognitive processing, and increased lesion burden in the posterior fossa adversely impact cognitive function, an important functional consequence of MS onset during childhood.
Thematic Reasoning and Theory of Mind. Accounting for Social Inference Difficulties in Schizophrenia
Authors: Corcoran Rhiannon , Frith Christopher D. 
Published: July 2015

Background Corcoran (2000, 2001) has suggested that theory of mind judgements can be arrived at using analogical reasoning skills and she has proposed that this is the route that people with schizophrenia take when they make inferences about others' mental states. Recent work has demonstrated a robust relationship between mental state inference and autobiographical memory, providing initial support for the model. This study examines the model further by exploring the assertion that in schizophrenia the ability to infer the mental states of others also depends upon effective social reasoning in conditional contexts. Method 59 people with a DSM IV diagnosis of schizophrenia and 44 healthy subjects performed four versions of the thematic selection task. The versions varied according to the familiarity and social nature of the material they incorporated. The same subjects also completed the Hinting Task, a measure of theory of mind and tests of intellectual functioning and narrative recall. Results The schizophrenia and the normal control groups differed in their performance on all of the measures except that of intellectual functioning. Explorations within the schizophrenia group indicated that social reasoning was most markedly affected in the patients with negative signs and in those with paranoid delusions while for the hinting task, those with negative signs performed significantly worse than those in remission but this difference seemed to be due to these patients' poorer narrative memory. There was evidence in the schizophrenia data to support the hypothesis of a relationship between theory of mind and social conditional reasoning. Conclusion This work provided further support for the idea that in patients with schizophrenia at least, judgements about the mental states of others are achieved using analogical reasoning.
A human liver microphysiology platform for investigating physiology, drug safety, and disease models
Authors: Vernetti Lawrence A , Senutovitch Nina , Boltz Robert , DeBiasio Richard , Ying Shun Tong , Gough Albert , Taylor D Lansing 
Published: July 2015

This paper describes the development and characterization of a microphysiology platform for drug safety and efficacy in liver models of disease that includes a human, 3D, microfluidic, four-cell, sequentially layered, self-assembly liver model (SQL-SAL); fluorescent protein biosensors for mechanistic readouts; as well as a microphysiology system database (MPS-Db) to manage, analyze, and model data. The goal of our approach is to create the simplest design in terms of cells, matrix materials, and microfluidic device parameters that will support a physiologically relevant liver model that is robust and reproducible for at least 28 days for stand-alone liver studies and microfluidic integration with other organs-on-chips. The current SQL-SAL uses primary human hepatocytes along with human endothelial (EA.hy926), immune (U937) and stellate (LX-2) cells in physiological ratios and is viable for at least 28 days under continuous flow. Approximately, 20% of primary hepatocytes and/or stellate cells contain fluorescent protein biosensors (called sentinel cells) to measure apoptosis, reactive oxygen species (ROS) and/or cell location by high content analysis (HCA). In addition, drugs, drug metabolites, albumin, urea and lactate dehydrogenase (LDH) are monitored in the efflux media. Exposure to 180 μM troglitazone or 210 μM nimesulide produced acute toxicity within 2–4 days, whereas 28 μM troglitazone produced a gradual and much delayed toxic response over 21 days, concordant with known mechanisms of toxicity, while 600 µM caffeine had no effect. Immune-mediated toxicity was demonstrated with trovafloxacin with lipopolysaccharide (LPS), but not levofloxacin with LPS. The SQL-SAL exhibited early fibrotic activation in response to 30 nM methotrexate, indicated by increased stellate cell migration, expression of alpha-smooth muscle actin and collagen, type 1, alpha 2. Data collected from the in vitro model can be integrated into a database with access to related chemical, bioactivity, preclinical and clinical information uploaded from external databases for constructing predictive models.
Water-Soluble Silicon Quantum Dots with Quasi-Blue Emission
Authors: Wang Yun , Wang Hao , Guo Jun , Wu Jiang , Gao Li J. , Sun Ying H. , Zhao J. , Zou Gui F. 
Published: July 2015

AbstractIn this study, water-soluble silicon quantum dots have quasi-blue emission at 390 nm by being capped with 1-vinylimidazole in resese micelles. As-obtained silicon quantum dots have a diameter of 2~5 nm and high crystallinity. The quasi-blue emission of the silicon quantum dots is likely attributed to the polarity of the capping ligands. Moreover, the silicon quantum dots are water-soluble and have photoluminescence nanosecond decay time, suggesting their potential application in biological field.
What’s in a name? Lower extremity fracture eponyms (Part 2)
Authors: Wong Philip Kin-Wai , Hanna Tarek N , Shuaib Waqas , Sanders Stephen M , Khosa Faisal 
Published: July 2015

Abstract
Eponymous extremity fractures are commonly encountered in the emergency setting. Correct eponym usage allows rapid, succinct communication of complex injuries. We review both common and less frequently encountered extremity fracture eponyms, focusing on imaging features to identify and differentiate these injuries. We focus on plain radiographic findings, with supporting computed tomography (CT) images. For each injury, important radiologic descriptors are discussed which may need to be communicated to clinicians. Aspects of management and follow-up imaging recommendations are included. This is a two-part review: Part 1 focuses on fracture eponyms of the upper extremity, while Part 2 encompasses fracture eponyms of the lower extremity.
Mapping Consistent Rice (Oryza sativa L.) Yield QTLs under Drought Stress in Target Rainfed Environments
Authors: Prince Silvas J , Beena R , Gomez S Michael , Senthivel S , Babu R Chandra 
Published: July 2015

Abstract

Background
Drought stress is a major limitation to rainfed rice production and yield stability. Identifying yield-associated quantitative trait loci (QTLs) that are consistent under drought stress predominant in target production environments, as well as across different genetic backgrounds, will help to develop high-yielding rice cultivars suitable for water-limited environments through marker-assisted breeding (MAB). Considerable progress has been made in mapping QTLs for drought resistance traits in rice; however, few have been successfully used in MAB.

Results
Recombinant inbred lines of IR20 × Nootripathu, two indica cultivars adapted to rainfed target populations of environments (TPEs), were evaluated in one and two seasons under managed stress and in a rainfed target drought stress environment, respectively. In the managed stress environment, the severity of the stress meant that measurements could be made only on secondary traits and biomass. In the target environment, the lines experienced varying timings, durations, and intensities of drought stress. The rice recombinant inbred lines exhibited significant genotypic variation for physio-morphological, phenological, and plant production traits under drought. Nine and 24 QTLs for physio-morphological and plant production traits were identified in managed and natural drought stress conditions in the TPEs, respectively. Yield QTLs that were consistent in the target environment over seasons were identified on chromosomes 1, 4, and 6, which could stabilize the productivity in high-yielding rice lines in a water-limited rainfed ecosystem. These yield QTLs also govern highly heritable key secondary traits, such as leaf drying, canopy temperature, panicle harvest index and harvest index.

Conclusion
Three QTL regions on chromosome 1 (RM8085), chromosome 4 (I12S), and chromosome 6 (RM6836) harbor significant additive QTLs for various physiological and yield traits under drought stress. The similar chromosomal region on 4 and 6 were found to harbor QTLs for canopy temperature and leaf drying under drought stress conditions. Thus, the identified large effect yield QTLs could be introgressed to develop rice lines with stable yields under varying natural drought stress predominant in TPEs.