bluuebunny/crossref_metadata_2025_split huggingface dataset:
Esthesioneuroblastoma in Young Boy: Masquerading as Invasive Aspergillosis
Authors: Bakshi Jaimanti , Gupta Bhumika , Dash Anil K , Panda Naresh K 
Published: March 2014

ABSTRACT
We present the case of a 15-year-old boy with a swelling and pain in right eye. He was diagnosed as esthesioneuroblastoma on the basis of radiology and histopathology.

How to cite this article
Bakshi J, Dash AK, Gupta B, Panda NK. Esthesioneuroblastoma in Young Boy: Masquerading as Invasive Aspergillosis. Clin Rhinol An Int J 2013;6(3):118-120.
Choanal Polyp Arising from Middle Turbinate
Authors: Singh Sunder , Gupta Manish 
Published: March 2014

ABSTRACT
Choanal polyp is the term used for benign, solitary soft tissue mass which extend toward the junction of nasal cavity and nasopharynx, i.e. choana. We report a rare case of choanal polyp arising from the middle turbinate and its successful treatment by endoscopic surgery. The complete resection of choanal polyp at the site of origin using an endoscope is usually sufficient and carries good prognosis without recurrence.

How to cite this article
Gupta M, Singh S. Choanal Polyp Arising from Middle Turbinate. Clin Rhinol An Int J 2013;6(3): 124-125.
Isolated Mucocele in an Infraorbital Ethmoidal-Haller Cell: A Unique Presentation
Authors: Mohindra Satyawati 
Published: March 2014

ABSTRACT
Haller cell, was first described by 18th century Swiss anatomist Albrecht von Haller.
Haller cells make up the posterior and superior wall of the ethmoid infundibulum. They can cause obstruction of ethmoidal infundibulum after enlargement. Isolated infection of the Haller cell is usually very rare and should be suspected in patients with visual complaints or facial pain. Diagnosis can be made on radiology.
Here, we report a patient with complaints of left-sided eye pain for the last 4 months which was finally diagnosed as Haller cell mucocele and successfully managed via endoscopic marsupialization.

How to cite this article
Mohindra S, Dhingra S. Isolated Mucocele in an Infraorbital Ethmoidal-Haller Cell: A Unique Presentation. Clin Rhinol An Int J 2013;6(3):129-130.
Large Frontal Sinus Mucopyocele
Authors: Shukla Anirudh , Dudeja Vivek 
Published: March 2014

ABSTRACTA mucocele is an epithelial-lined, mucus-containing sac completely filling the sinus and capable of expansion. This is in contradistinction to a blocked sinus cavity which simply contains mucus within the sinus. The frontal sinus is most commonly involved, whereas sphenoid, ethmoid, and maxillary mucoceles are rare. Frontal sinus is present just above the orbital cavity so any mass causing the expansion of floor of the frontal sinus leads to outwards (proptosis), downward and lateral displacement of orbit. If the cyst continues to expand within the orbital cavity, the mass may mimic an orbital growth or lesion pushing orbit laterally.A mucocele results from the obstruction of a sinus ostium, leading to the accumulation of secretions and the gradual, smooth expansion of the sinus. The mucocele contents often become increasingly desiccated and have an increasing protein content over time; therefore, they may show an increased density on CT scanning and variable degrees of hyperintensity on T1-weighted MRI sequences and hypointensity on T2-weighted MRI.Here we came across a patient who had right sided frontal mass causing proptosis and lateral displacement of right eye with vision limited only to perception of light. CT showed an expansile frontal mass with orbital displacement. We did external frontoethmoidectomy and a diagnosis of mucopyocele was made. The case, the experience and the outcome of external frontoethmiodectomy is being discussed.How to cite this articleShukla A, Dudeja V. Large Frontal Sinus Mucopyocele. Clin Rhinol An Int J 2013;6(3):131-135.
Unusual Foreign Body of Sino-orbital Region
Authors: Verma Hitesh , Chauhan Neha , Malik Archana , Brar Sarabjit 
Published: March 2014

ABSTRACT
Perforating injuries of the orbit involving the paranasal sinuses are uncommon. We report a case in which a large flat stone foreign body lodged in the anterior orbit and maxillary sinus was surgically removed by a combined approach by otolaryngologist and ophthalmologists.

How to cite this article
Gupta N, Verma H, Chauhan N, Malik A, Brar S. Unusual Foreign Body of Sino-orbital Region. Clin Rhinol An Int J 2013;6(3):136-138.
Metachronous Nodal and Nasal Rosai-Dorfman Disease presenting with Chronic Renal Failure
Authors: Bhat Shubha P , Prasad HL Kishan , Bhandary B Satheesh Kumar , Baikunje Shashidhar , Bhat Vadisha 
Published: March 2014

ABSTRACT
Rosai-Dorfman disease (RDD) is an uncommon non-neoplastic lymphoproliferative disorder. It usually manifests as bilateral, painless, massive cervical lymph node enlargement in children and young adults, hence the name sinus histiocytosis with massive lymphadenopathy. Extranodal involvement is observed in 25 to 40% of cases. Involvement of nasal cavity is rare and those presenting with renal failure are exceptional. We report a rare case of 16-year-old boy who was diagnosed as a case of RDD of cervical lymph node before 6 years, now presenting with nodular lesions in the nasal cavity and features of renal failure. The nasal lesion was confirmed to be RDD histologically.

How to cite this article
Bhat SP, Prasad HLK, Bhandary BSK, Baikunje S, Bhat V. Metachronous Nodal and Nasal Rosai Dorfman Disease presenting with Chronic Renal Failure. Clin Rhinol An Int J 2013;6(3):139-143.
Silent Sinus Syndrome: A Case Report and Review of Literature
Authors: Bhandary B Satheesh Kumar , Bhat Vadisha , Saldanha Marina , Scaria Sebin Tom 
Published: March 2014

ABSTRACT
Silent sinus syndrome is a rare condition affecting the maxillary sinus, resulting in spontaneous collapse of the sinus walls causing facial asymmetry and unilateral enophthalmos. The exact etiology of this condition is unknown. We report a case of a 20-year-old male presented with facial asymmetry with depression of right cheek associated with heaviness over right cheek, without any disturbance of vision or eye movement. Computed tomography (CT) scan of the paranasal sinus showed a relatively smaller and opacified right maxillary sinus with inward retraction of the roof, medial and posterolateral walls. He underwent endoscopic middle meatal antrostomy. On follow-up, patient is free of symptoms and the CT scan showed well-ventilated sinuses with arrest of the disease progression.

How to cite this article
Saldanha M, Bhat V, Bhandary BSK, Scaria ST. Silent Sinus Syndrome: A Case Report and Review of Literature. Clin Rhinol An Int J 2013;6(3):144-148.
Trichofolliculoma of the Nose: A Rare Disease
Authors: Agarwal AK , Passey JC , Brar Tripti , Dabas Shilpi , Arora Nikhil 
Published: March 2014

ABSTRACT

Purpose
The author wants to present a rare case of trichofolliculoma of nose.

Patients and methods
Clinical presentation, radiology, histopathological findings and management of the case has been presented.

Results
Patient has been on regular follow-up and planned for plastic reconstruction.

Conclusion
Trichofolliculoma, a benign hamortomatous lesion that develops at any age, usually presenting as a skin-colored nodule, correct histopathological diagnosis and treatment therefore, can lead to total removal of the benign lesion.

How to cite this article
Brar T, Passey JC, Dabas S, Agarwal AK, Arora N. Trichofolliculoma of the Nose: A Rare Disease. Clin Rhinol An Int J 2013;6(3):152-153.
The Therapeutic Challenges in Treating Duodenal Injury
Authors: Lucas Charles E 
Published: March 2014

ABSTRACT
Duodenal injuries pose many challenges in diagnosis and treatment. Unless suspected, pursued vigorously and treated by a well-designed plan, can cause significant morbidity and mortality.

How to cite this article
Lucas CE. The Therapeutic Challenges in Treating Duodenal Injury. J Trauma Critical Care Emerg Surg 2013;2(3):126-133.
Trends in Management of Traumatic Brain Injury by Emergency Physicians in Colombia
Authors: Rubiano Andres M , Alvis-Miranda Hernando Raphael , Alcalá-Cerra Gabriel , Moscote-Salazar Luis Rafael , Navas Claudia , Villa-Delgado Rosmery 
Published: March 2014

ABSTRACT

Background
Traumatic brain injury is a common cause of death in Colombia. The aim of this study was to evaluate the management of traumatic brain injury patients in Colombia.

Materials and methods
This study was conducted through a survey sent to 100 general practitioners in Colombia through an electronic format.

Results
Over the period of the study, data collected were about 59 physicians consecutively. The 31% of the respondents knew protocols for the management of traumatic brain injury.

Conclusion
Traumatic brain injury is one of the most important reasons for consultations in the emergency services in Colombia. We observed significant differences in the initial management of patients with this kind of injury. It requires the establishment of standard protocols and transmission thereof. The implementation of these strategies will contribute to a better patient outcome in Colombia.

How to cite this article
Alvis-Miranda HR, Navas C, Villa- Delgado R, Rubiano AM, Alcala-Cerra G, Moscote-Salazar LR. Trends in Management of Traumatic Brain Injury by Emergency Physicians in Colombia. J Trauma Critical Care Emerg Surg 2013;2(3):134-138.
TAPP Repair of an Obstructed Obturator Hernia
Authors: Aggarwal Nitin , Singh Ravinder , Bansal Darpan 
Published: March 2014

ABSTRACTIntestinal obstruction can be a result of diverse pathology depending upon the age of the patient. In the elderly, the most common cause appears to be malignancy or previous surgery. Inguinal hernia is another reason for acute intestinal obstruction, particularly in males. A rather rare cause of similar presentation in a female is obstructed obturator hernia. Due to its rarity and difficulty in diagnosis, most of the cases present late and, as a result, strangulation and necrosis of the bowel leads to high morbidity and mortality. We present a case of obstructed obturator hernia in a 80 years old female treated by laparoscopic transabdominal preperitoneal (TAPP) approach.How to cite this articleSingh R, Bansal D, Aggarwal N. TAPP Repair of an Obstructed Obturator Hernia. J Trauma Critical Care Emerg Surg 2013;2(3):146-148.
Housing Market Bubbles and Business Cycles in an Agent-Based Credit Economy
Authors: Erlingsson Einar Jon , Teglio Andrea , Cincotti Silvano , Stefansson Hlynur , Sturluson Jon Thor , Raberto Marco 
Published: March 2014

Abstract
This paper investigates the housing and mortgage markets by means of an agent-based macroeconomic model of a credit network economy. A set of computational experiments have been carried out in order to explore the effects of different households’ creditworthiness conditions required by banks in order to grant a mortgage. Results show that easier access to credit inflates housing prices, triggering a short run output expansion. However, the artificial economy becomes more unstable and prone to recessions. With stricter conditions the economy is more stable and does not fall into serious recessions, although a too severe regulation can slow down economic growth.
Against the Tide:
Authors: Kramer Michael P. 
Published: March 2014

ABSTRACT
A brief overview of the earliest scholarship on early Jewish American history and literature (including Cyrus Adler, Mayer Kayserling, Max J. Kohler, George Alexander Kohut, Isaac Markens, Oscar Straus, and Simon Wolf) is offered as an introduction to “Before the Flood,” a special issue of SAJL that presents recent, innovative scholarship on early Jewish American literature.
Cumberland's Benevolent Hebrew in Eighteenth-Century Britain and America
Authors: Bannet Eve Tavor 
Published: March 2014

ABSTRACT
This essay uses the different contemporary reactions of British critics and Jews to uncover the different facets of Richard Cumberland's understudied play The Jew (1794), which help to explain its enormous popularity among gentiles and the lack of enthusiasm among Jews, then moves across the Atlantic to examine the very different reception the play received from reviewers and audiences in America.
Grey Relational Analysis of Benefit of Surgical Management for Abdominal Aortic Aneurysm
Authors: Wang Kaifeng , Ren Shiyan , Qian Songyi , Liu Peng 
Published: March 2014

Abstract
Grey relational analysis was used to compare the long-term outcomes of endovascular repair (EVAR) versus open repair for patients with abdominal aortic aneurysm (AAA). Patients with AAA undergoing open repair (n = 133) or EVAR (n = 88) from July 1995 to January 2009 were studied retrospectively. Compared with EVAR, longer periods of postoperative intubation and hospital stay (P &lt; 0.001) were required for open repair. The operation time was significantly longer in open surgery than in EVAR (P &lt; 0.001). Patients in the open repair group required larger volumes of intraoperative blood transfusion than those in EVAR (P &lt; 0.001), and they had more of a trend of cardiac failure after surgery than those in the EVAR group. The operative mortality was similar in both groups. On follow-up, the all-cause mortality and the rates of ischemic legs within 5 years had no significant differences between the 2 procedures (P &gt; 0.05). The grey relational grades in EVAR and open repair were 0.673 and 0.936, respectively. Compared with open repair, patients with AAAs undergoing EVAR had fewer complications in the short term and had a similar all-cause mortality in the long term.
Gossypiboma Presenting as Coloduodenal Fistula – Report of a Rare Case With Review of Literature
Authors: Sistla Sarath Chandra , Ramesh Ananthakrishnan , Karthikeyan Vilvapathy Sengutuvan , Ram Duvuru , Ali Sheik Manwar , Subramaniam Raghavan Velayutham Sugi 
Published: March 2014

Abstract
The term gossypiboma is used to describe a mass of cotton matrix left behind in a body cavity intraoperatively. The most common site reported is the abdominal cavity. It can present with abscess, intestinal obstruction, malabsorption, gastrointestinal hemorrhage, and fistulas. A 37-year-old woman presented with pain in the right hypochondrium for 2 months following open cholecystectomy. As she did not improve with proton pump inhibitors, an esophagogastroduodenoscopy (EGD) was done, which showed a possible gauze piece stained with bile in the first part of the duodenum. Contrast-enhanced computed tomography (CECT) of the abdomen revealed an abnormal fistulous communication of the first part of duodenum with proximal transverse colon, with a hypodense, mottled lesion within the lumen of the proximal transverse colon plugging the fistula, suggestive of a gossypiboma. Excision of the coloduodenal fistula, primary duodenal repair, and feeding jejunostomy was done. The patient recovered well and is now tolerating normal diet. Coloduodenal fistula is usually caused by Crohn's disease, malignancy, right-sided diverticulitis, and gall stone disease. Isolated coloduodenal fistula due to gossypiboma has not been reported in the literature so far to the best of our knowledge. We report this case of coloduodenal fistula secondary to gossypiboma for its rarity and diagnostic challenge.
Effect of Topical Tetracycline on Seroma Formation in the Lichtenstein Technique: A Prospective Randomized Study
Authors: Turk Emin , Karagulle Erdal , Coban Gokcen , Yildirim Erkan , Moray Gokhan 
Published: March 2014

Abstract
We sought to investigate whether application of topical tetracycline has a limiting effect on seroma formation in patients undergoing hernia repair using a polypropylene mesh. This study was conducted in 96 patients undergoing an elective groin hernia repair. Patients were randomized and divided into 2 groups. After the graft was placed, and before external oblique muscle aponeurosis was closed, 5 mL tetracycline was administered on the graft in the tetracycline group (tetra group, n = 50), and 5 mL isotonic saline was administered in the control group (n = 46) without putting in a drain. Seroma checks via surface ultrasonography were done. Seroma amounts measured on the first day were significantly higher in the tetra group (P = 0.04). There were no significant differences regarding seroma measurements on the seventh day or in the first and second months. Topical tetracycline application has no limiting effect on seroma formation after a groin hernia operation.
The Role of 3-D Endorectal Ultrasound in Rectal Cancer: Our Experience
Authors: Kolev Nikola Y. , Tonev Anton Y. , Ignatov Valentin L. , Zlatarov Aleksander K. , Bojkov Vasil M. , Kirilova Tanya D. , Encheva Elitsa , Ivanov Krasimir 
Published: March 2014

Abstract
In the last 20 years, endorectal ultrasound (ERUS) has been one of the main diagnostic methods for locoregional staging of rectal cancer. ERUS is accurate modality for evaluating local invasion of rectal carcinoma into the rectal wall layers (T category). Adding the three-dimensional modality (3-D) increases the capabilities of this diagnostic tool in rectal cancer patients. We review the literature and report our experience in preoperative 3-D ERUS in rectal cancer staging. In the group of 71 patients, the staging of preoperative 3-D endorectal ultrasonography was compared with the postoperative morphologic examination. Three-dimensional ERUS preoperative staging was confirmed with morphologic evaluation in 66 out of 71 cases (92.9%). The detection sensitivities of rectal cancer with 3-D ERUS were as follows: T1, 92.8%; T2, 93.1%; T3, 91.6%; and T4, 100.0%; with specificity values of T1, 98.2%; T2, 95.4%; T3, 97.8%; and T4, 98.5%. Three-dimensional ERUS correctly categorized patients with T1, 97.1%; T2, 94.3%; T3, 95.7%; and T4, 98.5%. The percentage of total overstaged cases was 2.75% and that of understaged cases was 6.87%. The metastatic status of the lymph nodes was determined with a sensitivity of 79.1% (19 of 24), specificity of 91.4% (43 of 47), and diagnostic accuracy of 87.3% (62 of 71). In our experience, 3-D ERUS has the potential to become the diagnostic modality of choice for the preoperative staging of rectal cancer.
Synthesis of G‐N2‐(CH2)3‐N2‐G Trimethylene DNA Interstrand Cross‐Links
Authors: Gruppi Francesca , Johnson Salyard Tracy L. , Rizzo Carmelo J. 
Published: March 2014

AbstractThe synthesis of G‐N
2‐(CH2)3‐N
2‐G trimethylene DNA interstrand cross‐links (ICLs) in a 5′‐CG‐3′ and 5′‐GC‐3′ sequence from oligodeoxynucleotides containing N
2‐(3‐aminopropyl)‐2′‐deoxyguanosine and 2‐fluoro‐O
6‐(trimethylsilylethyl)inosine is presented. Automated solid‐phase DNA synthesis was used for unmodified bases and modified nucleotides were incorporated via their corresponding phosphoramidite reagent by a manual coupling protocol. The preparation of the phosphoramidite reagents for incorporation of N
2‐(3‐aminopropyl)‐2′‐deoxyguanosine is reported. The high‐purity trimethylene DNA interstrand cross‐link product is obtained through a nucleophilic aromatic substitution reaction between the N
2‐(3‐aminopropyl)‐2′‐deoxyguanosine‐ and 2‐fluoro‐O
6‐(trimethylsilylethyl)inosine‐containing oligodeoxynucleotides. Curr. Protoc. Nucleic Acid Chem. 56:5.14.1‐5.14.15. © 2014 by John Wiley & Sons, Inc.
Anti‐HIV Nucleoside Phosphonate GS‐9148 and Its Prodrug GS‐9131: Scale Up of a 2′‐F Modified Cyclic Nucleoside Phosphonate and Synthesis of Selected Amidate Prodrugs
Authors: Mackman Richard L. 
Published: March 2014

AbstractNucleoside phosphonate analogs are an important class of antiviral drugs for the treatment of HIV and HBV. The most recent nucleoside phosphonate to progress to clinical development is GS‐9131, a cyclic nucleoside phosphonate (CNP). This unit contains procedures for the synthesis of the parent CNP 2′‐Fd4AP (GS‐9148) and selected monoamidate and bisamidate prodrugs, including the monoamidate clinical prodrug GS‐9131. The first basic protocol of this unit details improved procedures for the preparation of 2′‐Fd4AP and related phosphonate esters by introduction of a hydroxylmethyl phosphonate ester regioselectively and stereoselectively onto a furanose core via a glycal intermediate. The method described is believed to be robust and flexible, allowing for a variety of analogs with other nucleobases or furanose 2′‐ring substitutions to be prepared. The preparation of monoamidate and bisamidate prodrugs either on the phosphonate diacid or its monophenyl ester is then described in the second and third basic protocols of this unit. Curr. Protoc. Nucleic Acid Chem. 56:14.10.1‐14.10.21. © 2014 by John Wiley & Sons, Inc.
The coupled moisture‐heat process of permafrost around a thermokarst pond in Qinghai‐Tibet Plateau under global warming
Authors: Li Shuangyang , Zhan Hongbin , Lai Yuanming , Sun Zhizhong , Pei Wansheng 
Published: March 2014

AbstractDue to environmental disturbances such as local human activity and global warming, melting of massive ground ice has resulted in thermokarst ponds, which are extensively distributed in the Qinghai‐Tibet Plateau (QTP). Besides the global warming, the thermokarst pond, as a major heat source, speeds up the moisture change and degradation of its surrounding permafrost. To analyze the long‐term coupled moisture‐heat process near a representative nonpenetrative thermokarst pond in a permafrost region, abundant temperature data over multiple years at different depths and horizontal distances from the center of the thermokarst pond have been collected at a field experimental station in QTP. A numerical model is built to analyze this thermokarst pond. The temperature and moisture processes of surrounding permafrost are simulated by this model and compared with measured temperature data. Our results show that if the rate of air temperature rise is 0.048°C/yr, which refers to a 2.4°C temperature rise over 50 years, the thawing fronts underneath the thermokarst pond move downward at a linear rate of 0.18 m/yr and the permafrost beneath the pond center would disappear after the year of 2281. Beyond that time, the impact range of the pond on the natural ground increases to about 50 m in horizontal direction. So a dish‐shape thawing zone occurs around the thermokarst pond. Simultaneously, the moisture state is greatly changed in 2281 and becomes completely different from that in 2013. All of these would inevitably deteriorate the ecological and environmental system in QTP.
The morphology of insular shelves as a key for understanding the geological evolution of volcanic islands: Insights from Terceira Island (Azores)
Authors: Quartau R. , Hipólito A. , Romagnoli C. , Casalbore D. , Madeira J. , Tempera F. , Roque C. , Chiocci F. L. 
Published: March 2014

AbstractShelves from volcanic ocean islands result from the competition between two main processes, wave erosion that forms and enlarges them and volcanic progradation that reduces their dimension. In places where erosion dominates over volcanism, shelf width can be used as a proxy for the relative age of the subaerial volcanic edifices and reconstruction of their extents prior to erosion can be achieved. In this study, new multibeam bathymetry and high‐resolution seismic reflection profiles are exploited to characterize the morphology of the insular shelves adjacent to each volcanic edifice of Terceira Island in order to improve the understanding of its evolution. Subaerial morphological and geological/stratigraphic data were also used to establish the connection between the onshore and offshore evolution. Shelf width contiguous to each main volcanic edifice is consistent with the known subaerial geological history of the island; most of the older edifices have wider shelves than younger ones. The shelf edge proved to be a very useful indicator in revealing the original extent of each volcanic edifice in plan view. Its depth was also used to reconstruct vertical movements, showing that older edifices like Serra do Cume‐Ribeirinha, Guilherme Moniz, and Pico Alto have subsided while more recent ones have not. The morphology of the shelf (namely the absence/presence of fresh lava flow morphologies and several types of erosional, depositional, and tectonic features) integrated with the analysis of the coastline morphology allowed us to better constrain previous geological interpretations of the island evolution.