bluuebunny/crossref_metadata_2025_split huggingface dataset:
Single‐incision multiport laparoendoscopic technique to repair retrocaval ureter using the Santosh PGI ureteric tacking fixation technique
Authors: Kumar Santosh , Shankaregowda Sriharsha Ajjoor , Devana Sudheer Kumar , Jain Siddharth , Singh Shrawan Kumar 
Published: October 2014

AbstractIntroductionA retrocaval ureter is a rare congenital anomaly associated with upper urinary tract obstruction. It can cause varying degrees of ureteral obstruction, and surgical intervention is often necessary. Here, we present a case of a retrocaval ureter repaired with the single‐incision multiport laparoendoscopic technique. We used a new fixation technique, Santosh PGI (Postgraduate Institute) ureteric tacking fixation technique, on both ureteric ends for easy ureteroureteric anastomosis.Materials and Surgical TechniqueA 45‐year‐old man presented with right loin pain. CT urography showed a retrocaval ureter. Because the patient was symptomatic, he underwent retrocaval ureter repair by the single‐incision multiport laparoendoscopic technique. A double‐J stent was placed in the right ureter with the patient in the lithotomy position. Then, the patient was placed in a modified flank position. After pneumoperitoneum was created, a 2.5‐cm incision was made in the umbilicus, and three conventional laparoscopic ports were inserted. The narrow retrocaval segment of ureter was resected, and both spatulated ureteric ends were fixed using the Santosh PGI ureteric tacking fixation technique, and ureteroureteral anastamosis was done. The duration of the procedure was 105 min. The patient was discharged from the hospital on postoperative day 3. Follow‐up intravenous pyelography at 3 months showed normal drainage.DiscussionThe single‐incision multiport laparoendoscopic technique is feasible and cost effective, has good cosmesis, and has minimal morbidity when performed by an expert laparoscopic surgeon. The Santosh PGI ureteric tacking fixation technique enabled us to suture easily and rapidly within the limited range of motion allowed by conventional laparoscopic instruments in SILS.
Thrombin generation assay identifies individual variability in responses to low molecular weight heparin in pregnancy: implications for anticoagulant monitoring
Authors: Chowdary Pratima , Adamidou Despoina , Riddell Anne , Aghighi Saman , Griffioen Anja , Priest Paul , Moghadam Lida , Kelaher Nicholas , Huq Farah Y. , Kadir Rezan A. , Tuddenham Edward G. , Gatt Alex 
Published: October 2014

SummaryLow molecular weight heparin (LMWH) given to inhibit coagulation and reduce the risk of thrombosis, is typically monitored by anti‐Xa assay. However, anti‐Xa levels may not necessarily provide an accurate measure of coagulation inhibition. Moreover, pregnancy is associated with hypercoagulability, which may compromise the efficacy of LMWH. We looked at the association between anti‐Xa levels and parameters of thrombin generation assay [TGA; area under the curve (AUC), peak height (PH) and time to peak (ttP)] using samples from 41 pregnant women receiving LMWH and 40 normal pregnant women controls. TGA results confirmed the physiological hypercoagulability of normal pregnancy (mean normalised values: AUC 119%; PH 157%; ttP 72%). Although anti‐Xa measures correlated with all three TGA parameters, this group correlation masked significant inter‐individual variability, demonstrated by the R2 value or coefficient of determination. Anti‐Xa levels contributed to 74% of variation in AUC values, 63% of variation in PH values and only 53% of variation in ttP values. The remainder reflects the contribution of patients’ intrinsic coagulation status. Hence, some patients with ‘safe’ anti‐Xa levels may potentially be under‐anticoagulated, particularly in pregnancy. Measuring coagulability directly with TGA may lower the risk of adverse events due to under‐anticoagulation in selected patients.
Follow‐up of extreme neonatal hyperbilirubinaemia in 5‐ to 10‐year‐old children: a Danish population‐based study
Authors: Vandborg Pernille Kure , Hansen Bo Moelholm , Greisen Gorm , Mathiasen Rene , Kasper Frederikke , Ebbesen Finn 
Published: October 2014

AimTo investigate whether infants with neonatal hyperbilirubinaemia but without intermediate or advanced bilirubin encephalopathy develop long‐term sequelae, with impairment of motor development, executive function, or hearing.MethodThis nested double‐cohort study included 167 exposed children (107 males, 60 females) born in Denmark 2000 to 2005 at gestational age ≥35 weeks with a total serum bilirubin ≥450 μmol/L (26.3mg/dL) and 163 age‐, sex‐, and gestational age‐matched unexposed children (103 males, 60 females). The children were examined at a mean age of 7.7 years (SD 1.7y) using the Movement Assessment Battery for Children–Second Edition (MABC‐2), pure tone audiometry, and the Behavioural Regulation Inventory of Executive Function (BRIEF) questionnaire.ResultsThe follow‐up rate was 70% of the eligible infants in the exposed group and 45% in the unexposed group. Mean difference was −0.2 (95% confidence interval [CI] −1.1 to 0.8) in adjusted standard score for MABC‐2 and 0.3 (95% CI −2.9 to 3.5) in adjusted BRIEF executive composite standard score. No children had significant hearing impairment or a diagnosis of cerebral palsy, attention‐deficit–hyperactive disorder, or autism spectrum disorder recorded in national registries.InterpretationNo evidence was found of an increased risk of deficits in motor development, executive function, or hearing in children with extreme hyperbilirubinaemia who did not have intermediate or advanced bilirubin encephalopathy.
A retrospective analysis of prevalence and characteristics of pre‐eruptive intracoronal resorption in unerupted teeth of the permanent dentition: a multicentre study
Authors: Uzun İ. , Gunduz K. , Canitezer G. , Avsever H. , Orhan K. 
Published: October 2014

AbstractAimThis multicentred study aimed to investigate the prevalence of pre‐eruptive intracoronal resorption (PIR) in unerupted teeth of the permanent dentition using a large sample of panoramic radiographs of a Turkish population.MethodologyRecords of 28 612 patients from three cities in the different regions of Turkey were screened retrospectively in this multicentred study. Patient records and panoramic radiographs were evaluated by three oral and maxillofacial radiologists in the sites. The following data were recorded: age, gender, number of unerupted teeth, number of teeth showing intracoronal resorption, affected tooth type and number of intracoronal resorptions in each case.ResultsOverall, 5554 patients had at least one unerupted tooth in 28 612 patients, with a prevalence of 19.4%. Of the 5554 patients screened, 2267 were female and 3287 were male. Intracoronal resorption was observed in 40 of 5554 subjects, with a frequency of 0.7%. The mean age of the patients was 35.9 years.ConclusionPre‐eruptive intracoronal resorption defects occurred in 40 subjects. Increased awareness and careful radiographic examination of unerupted teeth may improve early detection and treatment of PIR defects.
Quantitative FRET measurement using emission‐spectral unmixing with independent excitation crosstalk correction
Authors: ZHANG J. , LI H. , CHAI L. , ZHANG L. , QU J. , CHEN T. 
Published: October 2014

SummaryQuantification of fluorescence resonance energy transfer (FRET) needs at least two external samples, an acceptor‐only reference and a linked FRET reference, to calibrate fluorescence signal. Furthermore, all measurements for references and FRET samples must be performed under the same instrumental conditions. Based on a novel notion to predetermine the molar extinction coefficient ratio (RC) of acceptor‐to‐donor for the correction of acceptor excitation crosstalk, we present here a robust and independent emission‐spectral unmixing FRET methodology, Iem‐spFRET, which can simultaneously measure the E and RC of FRET sample without any external references, such that Iem‐spFRET circumvents the rigorous restriction of keeping the same imaging conditions for all FRET experiments and thus can be used for the direct measurement of FRET sample. We validate Iem‐spFRET by measuring the absolute E and RC values of standard constructs with different acceptor‐to‐donor stoichiometry expressed in living cells. Our results demonstrate that Iem‐spFRET is a simple and powerful tool for real‐time monitoring the dynamic intermolecular interaction within single living cells.
Growing into Export Markets: The Impact of Exporting on Firm‐level Investment in Indonesia
Authors: Rho Youngwoo , Rodrigue Joel 
Published: October 2014

AbstractThis paper documents the impact of exporting on capital accumulation across heterogeneous manufacturing firms in Indonesia. The findings show that entering export markets significantly increases investment behavior during the year of initial entry and for as much as three years after entry. The results imply that the investment rate among new exporters is 37% higher than non‐exporters in the year of entry and 14–26% higher in the three years after entry. Using detailed data on firm ownership, the paper further show that foreign‐owned affiliates invest at systematically higher rates upon entry into export markets. The estimates indicate that domestically owned exporters are potentially credit constrained and suggest that improving credit market access may increase the investment rate among domestic exporters by as much as 40% in the year of entry.
A Comparative Analysis of Accelerometer and Time–Motion Data in Elite Men’s Hockey Training and Competition
Authors: Polglaze Ted , Dawson Brian , Hiscock Daniel J. , Peeling Peter 
Published: October 2014

Purpose:To determine the relationship between distance covered and player load (PL: sum of accelerations in all 3 planes of movement) in hockey training and competition.Methods:Elite male hockey players (N = 24) wore player-tracking devices in 7 international matches and 7 training sessions. Players were arranged in 4 positional groups (strikers, attacking midfielders, defensive midfielders, defenders) in competition but had generic roles in training. Relationships between distance and PL were assessed in both absolute (m, AU) and relative (m/min, AU/min) terms and were compared between matches and training and between positions within matches, using the Fisher Z test.Results:In competition, the absolute distance–PL relationship was very large overall (r = .868), with no differences between positions. The relative distance–PL relationship was moderate overall (r = .486) and weaker in strikers than in defensive midfielders (Z = 1.785, P = .037) and defenders (Z = 1.690, P = .045). In training, the absolute distance–PL relationship was very large (r = .742), and large (r = .633) in relative terms. The relationship was stronger in competition than training for absolute values (Z = 2.824, P = .005) but not different for relative values.Conclusions:The strong relationship between these variables suggests that PL in hockey is mostly accumulated through running and other locomotor actions, such that PL is not effective in quantifying other activities (evasion, low stance) that contribute to physiological demands, particularly in training.
Increase in Injury Risk With Low Body Mass and Aerobic-Running Fitness in Elite Australian Football
Authors: Gastin Paul B. , Meyer Denny , Huntsman Emy , Cook Jill 
Published: October 2014

Purpose:To assess the relationships between player characteristics (including age, playing experience, ethnicity, and physical fitness) and in-season injury in elite Australian football.Design:Single-cohort, prospective, longitudinal study.Methods:Player characteristics (height, body mass, age, experience, ethnicity, playing position), preseason fitness (6-min run, 40-m sprint, 6 × 40-m sprint, vertical jump), and in-season injury data were collected over 4 seasons from 1 professional Australian football club. Data were analyzed for 69 players, for a total of 3879 player rounds and 174 seasons. Injury risk (odds ratio [OR]) and injury severity (matches missed; rate ratio [RR]) were assessed using a series of multilevel univariate and multivariate hierarchical linear models.Results:A total of 177 injuries were recorded with 494 matches missed (2.8 ± 3.3 matches/injury). The majority (87%) of injuries affected the lower body, with hamstring (20%) and groin/hip (14%) most prevalent. Nineteen players (28%) suffered recurrent injuries. Injury incidence was increased in players with low body mass (OR = 0.887, P = .005), with poor 6-min-run performance (OR = 0.994, P = .051), and playing as forwards (OR = 2.216, P = .036). Injury severity was increased in players with low body mass (RR = 0.892, P = .008), tall stature (RR = 1.131, P = .002), poor 6-min-run (RR = 0.990, P = .006), and slow 40-m-sprint (RR = 3.963, P = .082) performance.Conclusions:The potential to modify intrinsic risk factors is greatest in the preseason period, and improvements in aerobic-running fitness and increased body mass may protect against in-season injury in elite Australian football.
Automatic abstraction of imaging observations with their characteristics from mammography reports
Authors: Bozkurt Selen , Lipson Jafi A , Senol Utku , Rubin Daniel L 
Published: October 2014

Abstract
Background Radiology reports are usually narrative, unstructured text, a format which hinders the ability to input report contents into decision support systems. In addition, reports often describe multiple lesions, and it is challenging to automatically extract information on each lesion and its relationships to characteristics, anatomic locations, and other information that describes it. The goal of our work is to develop natural language processing (NLP) methods to recognize each lesion in free-text mammography reports and to extract its corresponding relationships, producing a complete information frame for each lesion.
Materials and methods We built an NLP information extraction pipeline in the General Architecture for Text Engineering (GATE) NLP toolkit. Sequential processing modules are executed, producing an output information frame required for a mammography decision support system. Each lesion described in the report is identified by linking it with its anatomic location in the breast. In order to evaluate our system, we selected 300 mammography reports from a hospital report database.
Results The gold standard contained 797 lesions, and our system detected 815 lesions (780 true positives, 35 false positives, and 17 false negatives). The precision of detecting all the imaging observations with their modifiers was 94.9, recall was 90.9, and the F measure was 92.8.
Conclusions Our NLP system extracts each imaging observation and its characteristics from mammography reports. Although our application focuses on the domain of mammography, we believe our approach can generalize to other domains and may narrow the gap between unstructured clinical report text and structured information extraction needed for data mining and decision support.
Clinical and angiographic outcomes after stent-assisted coiling of cerebral aneurysms with Enterprise and Neuroform stents: a comparative analysis of the literature
Authors: King Brent , Vaziri Sasha , Singla Amit , Fargen Kyle M , Mocco J 
Published: October 2014

IntroductionThe most widely used intracranial stents for stent-assisted coiling are Neuroform (NEU) and Enterprise stents (ENT). This study compares published outcomes between the ENT and NEU coil-assist systems and comments on the published safety and efficacy of stent-assisted coiling in general.MethodsA literature search was performed through PubMed for all published series of ENT or NEU stent-assisted coiling of cerebral aneurysms from 2004 to 2014. All studies including 10 or more published cases of stent-assisted coiling with ENT or NEU were included.Results47 studies met the inclusion criteria, containing 4238 aneurysms in 4039 patients. 2111 aneurysms were treated with NEU and 2127 were treated with ENT. Mean follow-up was 14.1 months. Overall, thromboembolic events occurred in 6.4% of aneurysms, intracranial hemorrhage (ICH) in 2.6%, permanent morbidity in 3.9%, and mortality in 2.3%. Initial and final 100% angiographic occlusion was seen in 53% and 69% of patients, respectively. Deployment failures (p<0.001), ICH (p=0.001), mortality among all patients (p=0.03), and recanalization (p=0.02) were more commonly reported in NEU treated aneurysms. The ENT system was also associated with higher reported complete occlusion at follow-up (p<0.001).ConclusionsThis literature review represents the largest and most robust comparison of stent-assisted coiling devices to date, containing over 4200 aneurysms in more than 4000 patients. Comparative analyses demonstrate that both devices are reported to be safe and effective with comparable permanent morbidity.
Impact of a Lifestyle Program on Vascular Insulin Resistance in Metabolic Syndrome Subjects: The RESOLVE Study
Authors: Vinet Agnes , Obert Philippe , Dutheil Frederic , Diagne Lamine , Chapier Robert , Lesourd Bruno , Courteix Daniel , Walther Guillaume 
Published: October 2014

AbstractContext and Objective:Impaired insulin-dependent vasodilation might contribute to microvascular dysfunction of metabolic syndrome (MetS). The aims of this study were to assess the insulin vasoreactivity in MetS, and to evaluate the effects of a lifestyle program.Design, Setting, Participants, and Outcome Measures:Laser Doppler measurements were used to assess cutaneous blood flux (CBF) and flowmotion in response to iontophoresis of insulin and acetylcholine (ACh) in 38 MetS and 18 controls. Anthropometric, plasma insulin, glycemia, and inflammatory markers were measured. MetS subjects (n = 24) underwent a 6-month lifestyle intervention (M6) with a 3-week residential program (D21).Results:The absolute and relative peak insulin and ACh CBF were significantly higher in controls than in MetS subjects. Significant inverse correlations were found between peak insulin CBF and glycemia, insulin and glycated hemoglobin, active plasminogen activator inhibitor-1 (PAI-1), C-reactive protein (CRP), and IL-6. With respect to flowmotion, MetS subjects showed lower values in total spectrum CBF and in all its components (except respiratory one). At D21 and M6, peak insulin CBF increased and was no longer different from control values whereas peak ACh CBF did not change. From D21, all the different components and the total CBF spectrum became similar to the control values. The changes in peak insulin CBF and in endothelial component between M6 and baseline were inversely correlated with the change in CRP and PAI-1.Conclusions:The local vasodilatory effects to insulin and its overall flowmotion are impaired in MetS subjects in relation to inflammation. The lifestyle intervention reversed this insulin-induced vascular dysfunction in parallel to decreased inflammation level.
First Results from Insemination With Sex-Sorted Semen in Dairy Heifers in Macedonia
Authors: Kochoski Ljupche , Filipov Zoran , Joshevski Ilcho , Ilievski Stevche , Davkov Filip 
Published: October 2014

Abstract
Science has been searching for a long time for a reliable method for controlling the sex of mammalian offspring. Recently, the application of specific modern cellular methodologies has led to the development of a flow cytometric system capable of differentiating and separating living X- and Y-chromosome-bearing sperm cells in amounts suitable for AI and therefore, commercialization of this sexing technology. The aim of this work was to present the first results of heifers that introduce bovine AI with sex sorted semen, for the first time in Macedonia. Insemination with sex sorted cryopreserved semen (2×106 spermatozoa per dose) imported from the USA was done at two dairy farms in ZK Pelagonija. In total, 74 heifers (Holstein Friesian) were inseminated. Inseminations were carried out in a timely manner following a modified OvSynch protocol. During the insemination, the sperm was deposited into the uterine horn ipsi lateral to the ovary where a follicle larger than 1.6 cm was detected by means of transrectal ultrasound examination. Pregnancy was checked by ultrasound on day 30 after the insemination. Overall, the average pregnancy rate in both farms was 43,24% (40,54% and 45,95%, for farm 1 and farm 2, respectively). All pregnant heifers delivered their calves following a normal gestation length (274,3 days in average) and of the 32 born calves, 30 (93,75%) were female. In conclusion, since the first results from inseminations with sex-sorted semen in dairy heifers in Macedonia are very promising, the introduction of this technique may bring much benefit to the local dairy sector. Average pregnancy rate seems similar with results obtained following ‘regular’ inseminations, notwithstanding the relatively low number of spermatozoa per insemination dose. Due to the latter, we however recommend inseminations only to be carried out by experienced technicians followinga TAI protocol and ultrasound examinations of the ovaries prior to insemination.
Quelles valeurs organisationnelles pour la génération Y ?
Authors: Dalmas Michel 
Published: October 2014

Quels sont les systèmes de valeurs partagés et recherchés par les membres de la génération Y, en entreprise ? Chercher une réponse à cette question nécessite d’identifier une échelle de mesure de valeurs individuelles, transposables au monde professionnel (Mc Donald et Gandz ; 1991, 1992). 2 915 jeunes de 18 à 25 ans ont répondu à une enquête relayée par l’ANDRH au niveau d’organismes de formation professionnels, durant la deuxième moitié de l’année 2012. Cette étude empirique quantitative a donné lieu à une analyse des données de type exploratoire sous SPSS (15). Des analyses en composantes principales ont permis d’identifier quatre facteurs significatifs, exprimant 44 % de la variance totale. De la part de la génération Y, il existerait donc une attente d’encadrement et de règles claires de la part de l’entreprise, une volonté de partage d’une ambiance de qualité et du bien vivre ensemble, l’acceptation du principe de diversité dans les groupes, et l’importance de valeurs.
De Thomas d'Aquin à Luther : le renoncement à un savoir du bien commun
Authors: Bourdin Bernard 
Published: October 2014

La notion de bien commun aux xiii e et xiv e siècles est inséparable de la réception chrétienne de la philosophie politique d’Aristote. En témoignent la théologie de saint Thomas d’Aquin et la pensée politique de Marsile de Padoue. Mais ces deux réceptions, l’une modérée, l’autre radicale, montrent la difficulté de conjoindre la double finalité, introduite par le christianisme, entre pouvoir temporel et pouvoir spirituel. D’une part, cette double finalité met à l’épreuve l’aspiration à l’autonomie de la communauté politique. D’autre part, la montée en puissance de cette aspiration, et aussi celle de l’individualisation du salut, met à l’épreuve la théologie comme savoir sur Dieu et sur le bien commun, ce dernier étant pensé analogiquement à la béatitude en Dieu. C’est sur ces trois défis que la méthode théologique de Luther introduit un nouveau paradigme autour de trois questions décisives : la doctrine de la justification par la foi seule, une anthropologie théologique délestée de l’aristotélisme et, comme conséquence des deux premières, un nouveau modèle des rapports entre pouvoirs temporel et spirituel. Par ce nouveau modèle, qui se fonde sur une disjonction radicale entre transcendance divine et immanence de la condition politique, la théologie de Luther renonce à un savoir du bien commun. Renoncement qui ouvre la voie à une prise en charge par la philosophie politique moderne de la finalité de la communauté politique et du statut qu’elle attribue à l’Église.