bluuebunny/crossref_metadata_2025_split huggingface dataset:
Single‐incision laparoscopic hepatic resection in patients with previous hepatic resections: A mini case series
Authors: Kim Guowei , Lau Arthur Chin‐Haeng , Chang Stephen Kin Yong 
Published: January 2014

AbstractSingle‐incision laparoscopic hepatic resection has been attracting increased attention from the surgical community in recent years. While there have been reports and studies on this procedure, none has suggested the possibility of doing repeated hepatic resections via a single incision. This report on three such cases aims to determine the feasibility and safety of this approach for such patients. Three patients who had previously had liver resections underwent single‐incision laparoscopic hepatic resection in our center. Patient demographics, type of port and instruments used, operating time, complications and incision length were collected. The operating time in each case was less than 230 min. The incision length for the single‐port device was 3.5 cm or less. The length of hospital stay was less than 5 days in each case. Intra‐operative blood loss was limited to 250 mL in each case. There were no immediate postoperative complications related to hepatic resection. Single‐incision laparoscopic hepatic resection is feasible for selected patients who have had previous hepatic resections. Because the port entry site for the single‐incision laparoscopic approach is usually slightly larger than that for the conventional approach, it is safer in re‐resection cases where there may be adhesions from previous surgery. Other possible benefits, such as cosmesis and reduced port‐associated morbidity, are mainly related to the use of only one small incision.
Rectal arteriovenous fistula resected laparoscopically after laparoscopic sigmoidectomy: A case report
Authors: Ushigome Hajime , Hayakawa Tetsushi , Morimoto Mamoru , Kitagami Hidehiko , Tanaka Moritsugu 
Published: January 2014

AbstractWe report a very rare case of rectal arteriovenous fistula following sigmoidectomy and discuss this case in the context of the existing literature. In April 2011, the patient, a man in his 60s, underwent laparoscopic sigmoidectomy with lymph node dissection for sigmoid colon cancer. Beginning in February 2012, he experienced frequent diarrhea. Abdominal contrast‐enhanced CT revealed local thickening of the rectal wall and rectal arteriovenous fistula near the anastomosis site. Rectitis from the rectal arteriovenous fistula was diagnosed. No improvement was seen with conservative treatment. Therefore, surgical resection was performed laparoscopically and the site of the lesion was confirmed by intraoperative angiography. The arteriovenous fistula was identified and resected. Postoperatively, diarrhea symptoms resolved, and improvement in rectal wall thickening was seen on abdominal CT. No recurrence has been seen as of 1 year postoperatively.
Robotics in general surgery: An evidence‐based review
Authors: Baek Se‐Jin , Kim Seon‐Hahn 
Published: January 2014

AbstractSince its introduction, robotic surgery has been rapidly adopted to the extent that it has already assumed an important position in the field of general surgery. This rapid progress is quantitative as well as qualitative. In this review, we focus on the relatively common procedures to which robotic surgery has been applied in several fields of general surgery, including gastric, colorectal, hepato‐biliary‐pancreatic, and endocrine surgery, and we discuss the results to date and future possibilities. In addition, the advantages and limitations of the current robotic system are reviewed, and the advanced technologies and instruments to be applied in the near future are introduced. Such progress is expected to facilitate the widespread introduction of robotic surgery in additional fields and to solve existing problems.
Effects of supplemental palygorskite instead of zinc oxide on growth performance, apparent nutrient digestibility and fecal zinc excretion in weaned piglets
Authors: Tang Chao H. , Wang Xiu Q. , Zhang Jun M. 
Published: January 2014

AbstractThe aim of this study was to determine the effects of dietary supplementation of palygorskite instead of zinc oxide (ZnO) on growth performance, apparent nutrient digestibility and zinc contents in serum and feces in weaned piglets. One hundred and sixty‐five piglets (28 days of age, 7.10 ± 0.86 kg) were allotted to five treatments on the basis of weight and sex. Each treatment included three replicates of 11 piglets. The piglets were fed the same basal diet supplemented with 0 mg/kg (control group), 1800 mg/kg, 2400 mg/kg, or 3000 mg/kg palygorskite or 2500 mg/kg ZnO for 28 days. There was no significant difference for incidence of diarrhea among the four treatments during the 0–14‐day feeding period. Compared with the control group, piglets offered diets supplemented with 1800 mg/kg palygorskite had higher (P < 0.05) average daily gain (ADG) and crude protein digestibility. Fecal digestibility of energy in 1800 mg/kg palygorskite and ZnO groups were higher (P < 0.05) than that in the control group. Both the zinc concentrations in serum and fecal zinc excretion in palygorskite groups and control group were all lower (P < 0.05) than that in the ZnO group. In conclusion, dietary supplementation with 1800 mg/kg palygorskite can improve growth performance and nutrient digestibility and can also decrease zinc excretion in feces in weaned piglets.
A Jungian Approach to Analytic Work in the Twenty‐First Century
Authors: Cochrane Maggie , Flower Steven , Mackenna Chris , Morgan Helen 
Published: January 2014

In Part 1 of this paper the authors summarize those key concepts in Jungian analytic theory which differentiate it from a psychoanalytic approach. To illustrate these perspectives and their application in clinical work, a patient is introduced. The authors elaborate on a particular dream with the proposition that it holds within it both an image of the internal world of the patient's personal psyche and something which might be viewed as archetypal and emerging from the collective unconscious.Part 2 focuses on more recent developments in Jungian analytic thinking. Michael Fordham's important work in extending Jungian theory into an understanding of infant development is summarized and illustrated by a clinical example. This is followed by a brief summary of how contemporary debate within the Jungian analytic community has been much affected by recent developments in areas outside the analytic discourse which have offered both a challenge to and an affirmation of certain Jungian concepts. Examples given are from emergence theory and neuroscience. The Jungian interest in such phenomena stems from a view of the human psyche as rooted in a wider world of matter, culture, history and an unconscious that is not only personal but also collective.
Neuropathologic Assessment of Dementia Markers in Identical and Fraternal Twins
Authors: Iacono Diego , Volkman Inga , Nennesmo Inger , Pedersen Nancy L. , Fratiglioni Laura , Johansson Boo , Karlsson David , Winblad Bengt , Gatz Margaret 
Published: January 2014

AbstractTwin studies are an incomparable source of investigation to shed light on genetic and non‐genetic components of neurodegenerative diseases, as Alzheimer's disease (AD). Detailed clinicopathologic correlations using twin longitudinal data and post‐mortem examinations are mostly missing. We describe clinical and pathologic findings of seven monozygotic (MZ) and dizygotic (DZ) twin pairs. Our findings show good agreement between clinical and pathologic diagnoses in the majority of the twin pairs, with greater neuropathologic concordance in MZ than DZ twins. Greater neuropathologic concordance was found for β‐amyloid than tau pathology within the pairs. ApoE4 was associated with higher β‐amyloid and earlier dementia onset, and importantly, higher frequency of other co‐occurring brain pathologies, regardless of the zygosity. Dementia onset, dementia duration, difference between twins in age at dementia onset and at death, did not correlate with AD pathology. These clinicopathologic correlations of older identical and fraternal twins support the relevance of genetic factors in AD, but not their sufficiency to determine the pathology, and consequently the disease, even in monozygotic twins. It is the interaction among genetic and non‐genetic risks which plays a major role in influencing, or probably determining, the degeneration of those brain circuits associated with pathology and cognitive deficits in AD.
Interferon gene expression in sputum cells correlates with the Asthma Index Score during virus‐induced exacerbations
Authors: Schwantes E. A. , Manthei D. M. , Denlinger L. C. , Evans M. D. , Gern J. E. , Jarjour N. N. , Mathur S. K. 
Published: January 2014

SummaryBackgroundThe majority of asthma exacerbations are related to viral respiratory infections. Some, but not all, previous studies have reported that low interferon responses in patients with asthma increase the risk for virus‐induced exacerbations.ObjectiveWe sought to determine the relationship between lower airway inflammatory biomarkers, specifically interferon gene expression, and the severity or presence of an exacerbation in asthmatics experiencing a naturally occurring viral infection.MethodsSputum samples were analysed from subjects in an asthma exacerbation study who experienced a confirmed viral infection. Subjects were monitored for daily symptoms, medication use and peak expiratory flow rate until baseline. Sputum samples were assessed for cell counts and gene expression.ResultsInterferon gamma expression was significantly greater in patients with asthma exacerbations compared to non‐exacerbating patients (P = 0.002). IFN‐α1, IFN‐β1 and IFN‐γ mRNA levels correlated with the peak Asthma Index (r = 0.58, P < 0.001; r = 0.57, P = 0.001; and r = 0.51, P = 0.004, respectively). Additionally, IL‐13, IL‐10 and eosinophil major basic protein mRNA levels were greater in patients with asthma exacerbations compared to non‐exacerbating patients (P = 0.03, P = 0.06 and P = 0.02, respectively), and IL‐13 mRNA correlated with the peak Asthma Index (P = 0.006).ConclusionsOur findings indicate that asthma exacerbations are associated with increased rather than decreased expression of interferons early in the course of infection. These findings raise the possibility that excessive virus‐induced interferon production during acute infections can contribute to airway inflammation and exacerbations of asthma.
Innate mucosal-associated invariant T (MAIT) cells are activated in inflammatory bowel diseases
Authors: Serriari N-E , Eoche M , Lamotte L , Lion J , Fumery M , Marcelo P , Chatelain D , Barre A , Nguyen-Khac E , Lantz O , Dupas J-L , Treiner E 
Published: January 2014

Summary
Inflammatory bowel diseases are characterized by a deregulated immune response targeting the gut bacterial flora. Mucosal-associated invariant T (MAIT) cells are major histocompatibility complex (MHC) class Ib-restricted innate-like lymphocytes with anti-bacterial functions. They display an effector/memory phenotype and are found in large numbers in the blood, mucosae and liver. They have also been implicated in inflammatory diseases such as multiple sclerosis. Therefore, we aimed to analyse the possible involvement of MAIT cells in Crohn's disease (CD) and ulcerative colitis (UC). To this end, a phenotypical and functional analysis of MAIT cells isolated from the blood of healthy subjects, CD and UC patients was undertaken. MAIT cells were also quantified in ileal biopsies of CD patients. The frequency of blood MAIT cells was specifically reduced in IBD patients compared with healthy donors, whereas it was dramatically greater in the inflamed versus healthy tissue. MAIT cells were activated as they expressed significantly more the Ki67 antigen, and this was accompanied by phenotypical changes such as increased expression of natural killer (NK)G2D and B and T lymphocyte attenuator (BTLA). Finally, in-vitro-activated MAIT cells from CD and UC patients secreted significantly more interleukin (IL)-17, together with a decreased interferon (IFN)-γ in CD but an increased IL-22 in UC. These data show that MAIT cells are activated in IBD, which results in an increased recruitment towards the inflamed tissues, an altered phenotype and a switch in the pattern of cytokine secretion. This is the first demonstration that MAIT cells are immune players in IBD, whose precise functions in this context need to be addressed.
Impact of child care arrangements on Australian children's cognitive outcome: moderation effects of parental factors
Authors: Lee Kyunghee 
Published: January 2014

AbstractThis study examines the effects of child care arrangements on children's cognitive outcomes. It is a secondary analysis, using data on 5107 children born in 2004 and their families from Growing Up in Australia: The Longitudinal Study of Australian Children. Data were collected in 2004 (Wave One), in 2006 (Wave Two) and in 2008 (Wave Three). This study asks (i) Do children receiving non‐parental child care have different cognitive developmental outcomes at ages 4–5, compared with those who never had non‐parental child care during the first 3 years of life? Do parental factors affect these associations?; and (ii) among children with non‐parental child care, do child care characteristics such as types of care, quantity, entry age and stability of child care affect child outcomes? Do parental factors affect child outcomes? The study's findings suggest that children in non‐parental child care had higher Peabody Picture Vocabulary Test scores at age 5. Among children in non‐parental child care arrangements, quantity and entry age of non‐parental child care affected children's cognitive developmental outcomes. Along with child care arrangements, parental mental health was associated with children's cognitive outcomes.
Exhaled nitric oxide after high‐intensity exercise at 2800 m altitude
Authors: Stang Julie , Bråten Veslemøy , Caspersen Cecilie , Thorsen Einar , Stensrud Trine 
Published: January 2014

SummaryBackgroundNitric oxide (NO) concentration in exhaled gas is a marker of some inflammatory processes in the lung, and endogenous NO plays a role in the physiological responses to exercise and altitude. The aim of this study was to compare changes in exhaled NO concentration 5–60 mins after high‐intensity exercise at 2800 m and at 180 m altitude.MethodsTwenty trained healthy volunteers (12 men), aged 19–28 years, were included in this open, crossover study. Subjects performed two exercise tests at different altitudes, 2800 m and 180 m, in a randomized order. The fraction of NO in exhaled gas (FENO) was measured 5 mins before and 5–60 mins after 8 mins of running on a treadmill at a heart rate (HR) of 90% of peak HR. Peak HR was assessed during a pretest at 180 m. Ambient temperature was 20·1°C (SD = 1·2) and relative humidity 40·2% (SD = 3·2). FENO measurements were corrected for altitude gas density effects and converted to partial pressure of NO (PENOcorr).ResultsPENOcorr was reduced from 1·47 (1·21, 1·73) millipascal (mPa) at baseline to 1·11 (0·87, 1·34) mPa 5 mins after exercise at 2800 m and from 1·54 (1·24, 1·84) to 1·04 (0·87, 1·22) mPa 5 mins after exercise at 180 m. There was no difference in PENOcorr between exercise at 2800 m and 180 m, and PENOcorr was normalized within 20 mins.ConclusionsExercise at 2800 m induces a similar acute reduction in exhaled nitric oxide concentration as compared with 180 m in healthy subjects.
The CTSA Consortium's Catalog of Assets for Translational and Clinical Health Research (CATCHR)
Authors: Shirey‐Rice Jana , Mapes Brandy , Basford Melissa , Zufelt Anneliese , Wehbe Firas , Harris Paul , Alcorn Michael , Allen David , Arnim Margaret , Autry Susan , Briggs Michael S. , Carnegie Andrea , Chavis‐Keeling Deborah , De La Pena Carlos , Dworschak Doris , Earnest Julie , Grieb Terri , Guess Marilyn , Hafer Nathaniel , Johnson Tesheia , Kasper Amanda , Kopp Janice , Lockie Timothy , Lombardo Vincetta , McHale Leslie , Minogue Andrea , Nunnally Beth , O'Quinn Deanna , Peck Kelly , Pemberton Kieran , Perry Cheryl , Petrie Ginny , Pontello Andria , Posner Rachel , Rehman Bushra , Roth Deborah , Sacksteder Paulette , Scahill Samantha , Schieri Lorri , Simpson Rosemary , Skinner Anne , Toussant Kim , Turner Alicia , Van der Put Elaine , Wasser June , Webb Chris D. , Williams Maija , Wiseman Lori , Yasko Laurel , Pulley Jill 
Published: January 2014

AbstractThe 61 CTSA Consortium sites are home to valuable programs and infrastructure supporting translational science and all are charged with ensuring that such investments translate quickly to improved clinical care. Catalog of Assets for Translational and Clinical Health Research (CATCHR) is the Consortium's effort to collect and make available information on programs and resources to maximize efficiency and facilitate collaborations. By capturing information on a broad range of assets supporting the entire clinical and translational research spectrum, CATCHR aims to provide the necessary infrastructure and processes to establish and maintain an open‐access, searchable database of consortium resources to support multisite clinical and translational research studies. Data are collected using rigorous, defined methods, with the resulting information made visible through an integrated, searchable Web‐based tool. Additional easy‐to‐use Web tools assist resource owners in validating and updating resource information over time. In this paper, we discuss the design and scope of the project, data collection methods, current results, and future plans for development and sustainability. With increasing pressure on research programs to avoid redundancy, CATCHR aims to make available information on programs and core facilities to maximize efficient use of resources.
Combined treatment with sodium butyrate and PD153035 enhances keratinocyte differentiation
Authors: Leon Carrion Sandra , Sutter Carrie Hayes , Sutter Thomas R. 
Published: January 2014

AbstractEpidermal growth factor (EGF) receptor (EGFR) signalling is a critical determinant of keratinocyte proliferation and differentiation in both normal and diseased skin. Here we explore the effects of combined treatment with the differentiation‐promoting agent sodium butyrate (SB) and the EGFR inhibitor (EGFRI) PD153035 on terminal differentiation of normal human epidermal keratinocytes (NHEKs). Cells treated with SB showed increased expression of the levels of mRNA and protein of the differentiation markers filaggrin and transglutaminase 1. Cotreatment with EGF significantly blunted these effects of SB. Combined treatment with SB and PD153035 alleviated these inhibitory actions of EGF, resulting in improved effects of decreased cell growth and increased terminal differentiation, relative to the individual treatments. These results indicate that the combined use of a differentiation‐promoting agent and an EGFR inhibitor may offer an additional approach to the management of hyperproliferative skin diseases.
Socially Responsible Apparel Labels: Effects on Fashionable Shoppers
Authors: Gam Hae Jin , Ma Yoon Jin , Banning Jennifer 
Published: January 2014

Although socially responsible (SR) labels can facilitate consumers' SR purchasing choices, research addressing the effectiveness of SR labels for apparel products is limited. The purpose of this study was to investigate the consumer segment that practices SR label reading behavior and plans to purchase SR apparel. An online survey was conducted with a random sample of U.S. consumers (N = 718). The researchers used cluster analysis to segment participants based on the participants' fashion orientation and shopping behavior into three groups: fashionable shoppers, regular shoppers, and uninvolved shoppers. These segments were used to develop a profile with regard to SR label behavior for apparel products. Results showed that consumers who were interested in fashion and shopping were more likely to be SR label users, to be more familiar with SR labels, they practiced increased SR apparel consumption, and they had greater intentions to purchase.
Arterial stiffness is associated with low skeletal muscle mass in Japanese community‐dwelling older adults
Authors: Sampaio Ricardo Aurélio Carvalho , Sewo Sampaio Priscila Yukari , Yamada Minoru , Yukutake Taiki , Uchida Marco Carlos , Tsuboyama Tadao , Arai Hidenori 
Published: January 2014

AimTo examine whether arterial stiffness, measured by the cardio‐ankle vascular index (CAVI), is associated with skeletal muscle mass index (SMI) in Japanese community‐dwelling older adults.MethodsData were collected from 175 participants through questionnaires and specific tests; the data included demographic, lifestyle and health characteristics, body mass index (BMI), and body composition features determined by the bioelectrical impedance analysis, ankle‐brachial index, the Mini‐Nutritional Assessment, handgrip strength (GS), walking speed and shuttle walking tests (SW), and arterial stiffness determined by the CAVI. Absolute SMI was dichotomized according to the first quintile, which determined low (n = 35) and normal (n = 140) SMI.ResultsParticipants with low SMI were older (P = 0.01), had more polypharmacy (P = 0.01), a lower BMI (P < 0.001), and fat mass index (P = 0.02), and had a greater risk of malnutrition (P < 0.001) than the normal group. Additionally, they showed poorer physical performance (GS and SW, P = 0.007 and 0.01, respectively) than the normal group. Furthermore, CAVI was associated with SMI even after adjustments (OR 1.82, 95% CI 1.14–2.90, P = 0.01).ConclusionsOur data showed that arterial stiffness is associated with low SMI in community‐dwelling older adults, even when adjusting by multiple factors, showing a close interaction of vascular aging and muscle mass decline. Geriatr Gerontol Int 2014; 14 (Suppl. 1): 109–114.
Cut‐off points of quadriceps strength, declines and relationships of sarcopenia‐related variables among Thai community‐dwelling older adults
Authors: Assantachai Prasert , Muangpaisan Weerasak , Intalapaporn Somboon , Sitthichai Kobkul , Udompunturak Suthipol 
Published: January 2014

AimTo define quadriceps strength cut‐off points for both sexes to be used in the working diagnosis of sarcopenia in older Asian people, and to investigate the age‐related declines of sarcopenia‐related variables and correlations between those variables among community‐dwelling older adults.MethodsThe present 3‐year prospective study was a part of the Bangkok Longitudinal Study by Siriraj Hospital for Older Men and Women. Data on 2149 participants aged ≥60 years were included in this analysis.ResultsThe quadriceps strength cut‐off points, identified based on mobility decline over 2 years of follow up, were 18.0 kg for men and 16.0 kg for women. When these cut‐off points were applied to the whole population aged ≥60 years (n = 950), the low quadriceps strength group had poorer results on all clinical variables when compared with the normal quadriceps strength group. Although nearly all of the sarcopenia‐related variables declined over 2 years of follow up in both older men and women, more significant differences between age groups were seen in older women. Quadriceps strength had the highest degree of correlation with total lean body mass in all age groups (r = 0.550–0.584, P < 0.001), followed by the 6‐min walk test in all age groups (r = 0.449–0.516, P < 0.001).ConclusionsThe quadriceps strength cut‐off points of 18.0 kg for older men and 16.0 kg for older women would be useful as a muscle strength measurement for use in any diagnostic algorithm; for example, sarcopenia diagnosis in older Asian people. Geriatr Gerontol Int 2014; 14 (Suppl. 1): 61–68.