bluuebunny/crossref_metadata_2025_split huggingface dataset:
Does the abundance of dominant trees affect diversity of a widespread tropical woodland ecosystem in Tanzania?
Authors: Shirima Deo D. , Totland Ørjan , Munishi Pantaleo K. T. , Moe Stein R. 
Published: June 2015

Abstract:Dominant woody species can determine the structure and composition of a plant community by affecting environmental conditions experienced by other species. We explored how dominant tree species affect the tree species richness, diversity, evenness and vertical structural heterogeneity of non-dominant species in wet and dry miombo woodlands of Tanzania. We sampled 146 plots from eight districts with miombo woodlands, covering a wide range of topographic and climatic conditions. We recorded 217 woody plant species belonging to 48 families and 122 genera. Regression analysis showed significant negative linear associations between tree species richness, relative species profile index of the non-dominant and the relative abundance of the dominant tree species (Brachystegia spiciformisandBrachystegia microphyllain wet, andBrachystegia spiciformisandJulbernardia globiflorain dry miombo woodlands). Shannon diversity and evenness had strong non-linear negative relationships with relative abundance of dominant tree species. A large number of small individual stems from dominant and non-dominant tree species suggesting good regeneration conditions, and intensive competition affecting survival. We suggest that dominant miombo tree species are suppressing the non-dominant miombo tree species, especially in areas with high recruitments, perhaps because of their important adaptive features (extensive root systems and ectomycorrhizal associations), which enhance their ability to access limited nutrients.
Consonant lenition as a sociophonetic variable in Murrinh Patha (Australia)
Authors: Mansfield John Basil 
Published: June 2015

AbstractIn recent years, the typological and geographic range of languages subjected to sociophonetic study has been expanding, though until now Australian Aboriginal languages have been absent from this subdiscipline. This first sociophonetic study of an Australian language, Murrinh Patha, shows a type of consonant lenition that is notably distinct from the better known examples in Standard Average European languages, effecting /p/ and /k/ primarily in the onset of stressed, usually word-initial syllables. Young men lenite more frequently than older men do, and paternal heritage from the neighboring Marri language group also predicts more frequent lenition. The latter influence may be the result of intense language contact brought about by recent settlement of diverse language groups at the Catholic Mission of Port Keats.
The emergence of negative concord in Santa María Chiquimula K'ichee’ (Mayan): A variationist perspective
Authors: Romero Sergio 
Published: June 2015

ABSTRACTThis paper is a quantitative study of the emergence of negative concord in Santa María Chiquimula K'ichee’, apparently the only known case of negative concord in the Mayan stock. It is the latest development in a series of recent changes in the syntax of negative clauses in K'ichee’ (Romero, 2012). Using apparent time and comparative cross-dialectal data, I show that negative concord in this variety is a change in progress that started no earlier than the turn of the 20th century.
Constraints on ellipsis alternation: A view from the history of English
Authors: Nykiel Joanna 
Published: June 2015

AbstractI offer a diachronic perspective on English ellipsis alternation, or the alternation between inclusion and omission of prepositions from remnants under sluicing and bare argument ellipsis. The relative freedom to omit prepositions from remnants has not been stable in English; this freedom is connected to the strength of semantic dependencies between prepositions and verbs. Remnants without prepositions are first attested, but remain less frequent than remnants with prepositions, as late as Early Modern English and gain in frequency following this period. I demonstrate that three constraints—correlate informativity, structural persistence, and construction type—predict ellipsis alternation in Early and Late Modern English. However, predicting ellipsis alternation in present-day English requires semantic dependencies in addition to the three constraints. The constraints can be subsumed under principles of language processing and production (considerations of accessibility, a tendency to reuse structure, and a conventionalized performance preference for efficiently accessing constituents that form processing domains), permitting a unified processing account of ellipsis alternation with cross-linguistic coverage.
Neural responses to monetary incentives among self-injuring adolescent girls
Authors: Sauder Colin L. , Derbidge Christina M. , Beauchaine Theodore P. 
Published: June 2015

AbstractRates of self-inflicted injury among adolescents have risen in recent years, yet much remains to be learned about the pathophysiology of such conduct. Self-injuring adolescents report high levels of both impulsivity and depression behaviorally. Aberrant neural responding to incentives, particularly in striatal and prefrontal regions, is observed among both impulsive and depressed adolescents, and may mark common vulnerability to symptoms of anhedonia, irritability, and low positive affectivity. To date, however, no studies have examined associations between central nervous system reward responding and self-injury. In the current study, self-injuring (n= 19) and control (n= 19) adolescent females, ages 13–19 years, participated in a monetary incentive delay task in which rewards were obtained on some trials and losses were incurred on others. Consistent with previous findings from impulsive and depressed samples, self-injuring adolescents exhibited less activation in both striatal and orbitofrontal cortex regions during anticipation of reward than did controls. Self-injuring adolescents also exhibited reduced bilateral amygdala activation during reward anticipation. Although few studies to date have examined amygdala activity during reward tasks, such findings are common among adults with mood disorders and borderline personality disorder. Implications for neural models of impulsivity, depression, heterotypic comorbidity, and development of both self-injury and borderline personality traits are discussed.
Japanese modern municipal retail and wholesale markets in comparison with European markets
Authors: HARADA MASAMI 
Published: June 2015

ABSTRACTThis article seeks to assess the relevance of market ideas outside the European context. In pre-modern Japan, there was neither street market nor retail market but wholesale markets in cities. Feudal lords permitted wholesale dealers to operate in the market as long as the dealers paid either tribute such as fish or tax money to their lords. The Meiji Restoration in the late nineteenth century brought an end to the feudal system. In modern Japan, the problem of food supply in the city arose after the Japanese-Russo War. The Rice Riots broke out in 1918, and drove many cities to open their own municipal retail markets in order to supply urban dwellers with food and daily necessities. Fixed and marked price and cash payment were the operating principles of those municipal retail markets. These principles represented the characteristic features of the modern retail trade. Such municipal retail markets played an important role in the modernization of the retail trade in Japan.
The streets for the people: London's street markets 1850–1939
Authors: KELLEY VICTORIA 
Published: June 2015

ABSTRACTThis article analyses London's street markets in the years between 1850 and 1939. It shows how this was a period of significant growth for street markets, with both steeply increasing numbers of markets and a steady increase in the number of stalls overall. These markets were informal and unauthorized for much of the period under discussion; the administrative/local government context was complex, and competing authorities (the City of London, London County Council, metropolitan boroughs and national government) hesitated in regulating the organic growth of street market trading, while also recognizing the contribution it made to bringing cheap food and commodities to the population of London. It will be argued that the street market, far from being merely the survival of a primitive form of retail, flourished in response to modernity in London. It should be analysed alongside other developing forms of retail, and considered for its contribution to the culture and material culture of the city.
Police forces and political crises: revolutions, policing alternatives and institutional resilience in Paris, 1848–1871
Authors: DELUERMOZ QUENTIN 
Published: June 2015

ABSTRACT:This article examines the relationship between police forces and Parisian society during the two final revolutions of nineteenth-century France in 1848 and 1871. The comparison between these two events reveals the existence of an alternative revolutionary project of ‘urban police’. It also shows, however, the relatively weak impact of these moments on long-term transformations of police organizations. This is all the more notable if we consider the Second Empire's municipal reform of 1854 that had a deep impact on the landscape of the Parisian police. Observing this general sequence helps thus to explore the modifications of police powers during revolutionary moments, and the dynamics of the non-linear transformation of police orders and urban societies in the nineteenth century.
Bungowannah virus – a probable new species of pestivirus – what have we found in the last 10 years?
Authors: Kirkland P. D. , Read A. J. , Frost M. J. , Finlaison D. S. 
Published: June 2015

AbstractBungowannah virus was discovered following an outbreak of stillbirths and sudden death in young pigs. Affected animals consistently showed a myocardopathy with signs of cardiac failure. After virus isolation and PCR investigations were unsuccessful, direct fetal inoculation was undertaken. Nucleic acid purified from serum from infected fetuses was subjected to sequence-independent single-primer amplification and nucleic acid sequencing. Sequences consistent with a pestivirus were obtained. The entire genome was identified but was genetically remote from the recognized pestivirus species. This virus was not recognized by pan-pestivirus reactive monoclonal antibodies but was subsequently detected in cell cultures by immunoperoxidase staining using convalescent sow serum. Experimental infections of sows at different stages of gestation reproduced the myocarditis syndrome. Pre-weaning losses of 70 and 29% were observed following infection at days 35 and 90, respectively. Piglets infected at day 35 were shown to be persistently infected, while chronic infections were observed after fetal infection at day 55. Chronically infected piglets showed growth retardation and were viremic for up to 7 months. Myocarditis was associated with infection in late gestation (day 90). Non-pregnant sheep and cattle have been experimentally infected but with no evidence of disease. Infection of pregnant cattle in early gestation resulted in both maternal and fetal infection, but all infected fetuses mounted an antibody response to the virus. Analysis of the nucleic acid sequence confirmed that Bungowannah has a number of changes not observed in other pestiviruses. Genes encoding some of the structural proteins remain fully functional when inserted into a bovine viral diarrhea virus (BVDV) backbone. Cell culture-based studies have shown that Bungowannah virus will grow in cells extending from humans to bats as well as farm animals.
Perspective on BVDV control programs
Authors: Givens M. Daniel , Newcomer Benjamin W. 
Published: June 2015

AbstractPrograms for control and eradication of bovine viral diarrhea virus (BVDV) are often considered prudent when the expense of a control program within a specified time frame effectively prevents loss due to disease and the expense of control does not exceed the costs associated with infection. In some geographic areas, concerns about animal welfare or desires to reduce antibiotic usage may motivate BVDV control even when control programs are associated with a lack of financial return on investment. In other geographic areas, concerns about financial return on investment may be the key motivating factor in considering implementation of BVDV control programs. Past experiences indicate that systematic, well-coordinated control programs have a clear potential for success, while voluntary control programs in cultures of distributed decision-making often result in notable initial progress that ultimately ends in dissolution of efforts. Segmentation of the cattle industry into cow–calf producers, stocker/backgrounders, and feedlot operators amplifies the distribution of decision-making regarding control programs and may result in control measures for one industry segment that are associated with significant costs and limited rewards. Though the host range of BVDV extends well beyond cattle, multiple eradication programs that focus only on testing and removal of persistently infected (PI) cattle have proven to be effective in various countries. While some individuals consider education of producers to be sufficient to stimulate eradication of BVDV, research surrounding the adoption of innovative health care procedures suggests that the process of adopting BVDV control programs has a social element. Collegial interactions and discussions may be crucial in facilitating the systematic implementation necessary to optimize the long-term success of control programs. Compulsory control programs may be considered efficient and effective in some regions; however, in a nation where individual identification of cattle remains voluntary, the likelihood of effective compulsion to control BVDV within a farm or ranch appears to be very unlikely. While currently available diagnostic tests are sufficient to support BVDV eradication via systematic, well-coordinated programs, the development of a diagnostic procedure to safely and consistently detect the gestation of a PI fetus after 5 months of gestation would be a valuable research breakthrough. This desired testing modality would allow diagnosis of PI calves, while the dam continues to provide biocontainment of the infected fetus. This development could speed the progress of control programs in achieving the goal of BVDV control and eventual eradication.
Genetic variability and distribution of Classical swine fever virus
Authors: Beer Martin , Goller Katja V. , Staubach Christoph , Blome Sandra 
Published: June 2015

AbstractClassical swine fever is a highly contagious disease that affects domestic and wild pigs worldwide. The causative agent of the disease is Classical swine fever virus (CSFV), which belongs to the genusPestiviruswithin the familyFlaviviridae. On the genome level, CSFV can be divided into three genotypes with three to four sub-genotypes. Those genotypes can be assigned to distinct geographical regions. Knowledge about CSFV diversity and distribution is important for the understanding of disease dynamics and evolution, and can thus help to design optimized control strategies. For this reason, the geographical pattern of CSFV diversity and distribution are outlined in the presented review. Moreover, current knowledge with regard to genetic virulence markers or determinants and the role of the quasispecies composition is discussed.
Innate and adaptive immune responses toin uteroinfection with bovine viral diarrhea virus
Authors: Hansen Thomas R. , Smirnova Natalia P. , Webb Brett T. , Bielefeldt-Ohmann Helle , Sacco Randy E. , Van Campen Hana 
Published: June 2015

AbstractInfection of pregnant cows with noncytopathic (ncp) bovine viral diarrhea virus (BVDV) induces rapid innate and adaptive immune responses, resulting in clearance of the virus in less than 3 weeks. Seven to 14 days after inoculation of the cow, ncpBVDV crosses the placenta and induces a fetal viremia. Establishment of persistent infection with ncpBVDV in the fetus has been attributed to the inability to mount an immune response before 90–150 days of gestational age. The result is ‘immune tolerance’, persistent viral replication and shedding of ncpBVDV. In contrast, we describe the chronic upregulation of fetal Type I interferon (IFN) pathway genes and the induction of IFN-γ pathways in fetuses of cows infected on day 75 of gestation. Persistently infected (PI) fetal IFN-γ concentrations also increased at day 97 at the peak of fetal viremia and IFN-γ mRNA was significantly elevated in fetal thymus, liver and spleen 14–22 days post maternal inoculation. PI fetuses respond to ncpBVDV infection through induction of Type I IFN and IFN-γ activated genes leading to a reduction in ncpBVDV titer. We hypothesize that fetal infection with BVDV persists because of impaired induction of IFN-γ in the face of activated Type I IFN responses. Clarification of the mechanisms involved in the IFN-associated pathways during BVDV fetal infection may lead to better detection methods, antiviral compounds and selection of genetically resistant breeding animals.
Site-specific processing of Ras and Rap1 Switch I by a MARTX toxin effector domain
Authors: Antic Irena , Biancucci Marco , Zhu Yueming , Gius David R. , Satchell Karla J. F. 
Published: June 2015

AbstractRas (Rat sarcoma) protein is a central regulator of cell growth and proliferation. Mutations in the RAS gene are known to occur in human cancers and have been shown to contribute to carcinogenesis. In this study, we show that the multifunctional-autoprocessing repeats-in-toxin (MARTX) toxin-effector domain DUF5Vv from Vibrio vulnificus to be a site-specific endopeptidase that cleaves within the Switch 1 region of Ras and Rap1. DUF5Vv processing of Ras, which occurs both biochemically and in mammalian cell culture, inactivates ERK1/2, thereby inhibiting cell proliferation. The ability to cleave Ras and Rap1 is shared by DUF5Vv homologues found in other bacteria. In addition, DUF5Vv can cleave all Ras isoforms and KRas with mutations commonly implicated in malignancies. Therefore, we speculate that this new family of Ras/Rap1-specific endopeptidases (RRSPs) has potential to inactivate both wild-type and mutant Ras proteins expressed in malignancies.
Exploring the Effects of Different Types of Surfactants on Zebrafish Embryos and Larvae
Authors: Wang Yanan , Zhang Yuan , Li Xu , Sun Mingzhu , Wei Zhuo , Wang Yu , Gao Aiai , Chen Dongyan , Zhao Xin , Feng Xizeng 
Published: June 2015

AbstractCurrently, surfactants are widely distributed in the environment. As organic pollutants, their toxicities have drawn extensive attention. In this study, the effects of anionic [sodium dodecyl sulphate (SDS) ], cationic [dodecyl dimethyl benzyl ammonium chloride (1227)] and non-ionic [fatty alcohol polyoxyethylene ether (AEO) ] surfactants on zebrafish larval behaviour were evaluated. Five behavioural parameters were recorded using a larval rest/wake assay, including rest total, number of rest bouts, rest bouts length, total activity and waking activity. The results revealed that 1227 and AEO at 1 μg/mL were toxic to larval locomotor activity and that SDS had no significant effects. Moreover, we tested the toxicities of the three surfactants in developing zebrafish embryos. AEO exposure resulted in smaller head size, smaller eye size and shorter body length relative to SDS and 1227. All three surfactants incurred concentration-dependent responses. Furthermore, in situ hybridisation indicated that smaller head size may be associated with a decreased expression of krox20. The altered expression of ntl demonstrated that the developmental retardation stemmed from inhibited cell migration and growth. These findings provide references for ecotoxicological assessments of different types of surfactants and play a warning role in the application of surfactants.
Universal freezing of quantum correlations within the geometric approach
Authors: Cianciaruso Marco , Bromley Thomas R. , Roga Wojciech , Lo Franco Rosario , Adesso Gerardo 
Published: June 2015

AbstractQuantum correlations in a composite system can be measured by resorting to a geometric approach, according to which the distance from the state of the system to a suitable set of classically correlated states is considered. Here we show that all distance functions, which respect natural assumptions of invariance under transposition, convexity and contractivity under quantum channels, give rise to geometric quantifiers of quantum correlations which exhibit the peculiar freezing phenomenon, i.e., remain constant during the evolution of a paradigmatic class of states of two qubits each independently interacting with a non-dissipative decohering environment. Our results demonstrate from first principles that freezing of geometric quantum correlations is independent of the adopted distance and therefore universal. This finding paves the way to a deeper physical interpretation and future practical exploitation of the phenomenon for noisy quantum technologies.
Physical supports from liver cancer cells are essential for differentiation and remodeling of endothelial cells in a HepG2-HUVEC co-culture model
Authors: Chiew Geraldine Giap Ying , Fu Afu , Perng Low Kar , Qian Luo Kathy 
Published: June 2015

AbstractBlood vessel remodeling is crucial in tumor growth. Growth factors released by tumor cells and endothelium-extracellular matrix interactions are highlighted in tumor angiogenesis, however the physical tumor-endothelium interactions are highly neglected. Here, we report that the physical supports from hepatocellular carcinoma, HepG2 cells, are essential for the differentiation and remodeling of endothelial cells. In a HepG2-HUVEC co-culture model, endothelial cells in direct contact with HepG2 cells could differentiate and form tubular structures similar to those plated on matrigel. By employing HepG2 cell sheet as a supportive layer, endothelial cells formed protrusions and sprouts above it. In separate experiments, fixed HepG2 cells could stimulate endothelial cells differentiation while the conditioned media could not, indicating that physical interactions between tumor and endothelial cells were indispensable. To further investigate the endothelium-remodeling mechanisms, the co-culture model was treated with inhibitors targeting different angiogenic signaling pathways. Inhibitors targeting focal adhesions effectively inhibited the differentiation of endothelial cells, while the growth factor receptor inhibitor displayed little effect. In conclusion, the co-culture model has provided evidences of the essential role of cancer cells in the differentiation and remodeling of endothelial cells and is a potential platform for the discovery of new anti-angiogenic agents for liver cancer therapy.
Biological determinants of bladder cancer gene expression subtypes
Authors: Aine Mattias , Eriksson Pontus , Liedberg Fredrik , Sjödahl Gottfrid , Höglund Mattias 
Published: June 2015

AbstractMolecular stratification of tumors by gene expression profiling has been applied to a large number of human malignancies and holds great promise for personalized treatment. Comprehensive classification schemes for urothelial carcinoma have been proposed by three separate groups but have not previously been evaluated simultaneously in independent data. Here we map the interrelations between the proposed molecular subtypes onto the intrinsic structure of a rich independent dataset and show that subtype stratification within each scheme can be explained in terms of a set of common underlying biological processes. We highlight novel biological and genomic drivers of urothelial carcinoma molecular subtypes and show that tumors carrying genomic aberrations characteristic of distinct molecular pathways converge on a common top level phenotype corresponding to the two major molecular subtypes of non-muscle invasive disease.