bluuebunny/crossref_metadata_2025_split huggingface dataset:
What are prison offender managers’ experiences of delivering New Me MOT?
Authors: Pagano Catia , Fusco Louise 
Published: July 2024

Purpose
The New Me MOT toolkit is part of the His Majesty’s Prison and Probation Service (HMPPS) accredited offending behaviour programmes, consisting of a series of short exercises that enable offender managers to support graduates of the programmes to generalise their learning. This study was commissioned by HMPPS with the aim to evaluate the delivery of the toolkit in custody, through exploring probation prison offender managers’ (POMs’) delivery experiences.

Design/methodology/approach
Convenience sampling was used to recruit participants from male prisons in England and Wales via semi-structured interviews (n = 8), and data was analysed through thematic analysis.

Findings
Five overarching themes with related subthemes were identified: New Me MOT is useful, flexible toolkit, motivation of the prisoner, limited resources and lack of structured guidance.

Research limitations/implications
Future research should consider investigating POMs’ experiences from other prison establishments, to explore any possible additional findings about what impacts New Me MOT delivery in custody.

Practical implications
Suggestions were made to improve the future delivery of the toolkit across HMPPS. This is fundamental to support the behavioural change process.

Originality/value
No previous research on New Me MOT exists. This study findings showed that, based on the experiences of eight POMs interviewed, there are factors which aid and obstruct the toolkit delivery. This suggests that POMs might miss opportunities to prioritise generalisation of work for those most in need, target their criminogenic needs and tailor the toolkit content according to participants’ personal circumstances.
Comparing teacher beliefs and actions during collaborative geographical inquiry
Authors: Kriewaldt Jeana , Robertson Lucy , Ziebell Natasha , Lee Shu Jun 
Published: July 2024

AbstractThe importance of between‐desk instruction during inquiry‐based learning to deepen learning is well recognised in some curriculum areas but remains under‐researched in geography. Inquiry‐based learning incorporates the use of generative questions and inquiry methods to support student‐driven investigations. This paper reports on a study of teacher–student interactions during geography inquiry‐based learning. A cross‐case fine‐grained analysis of two teachers’ video‐recorded lessons in a classroom laboratory using a kikan‐shido coding framework showed that “guiding” was the dominant between‐desk function used. The teachers differed in whether guiding was mainly used for task completion or to deepen student understanding. Semi‐structured interviews revealed that the characteristics and sequence of these guiding actions were influenced by teachers’ beliefs. Those beliefs mediated how teachers guided students during the inquiry, debunking a dichotomous view of inquiry‐based learning as either teacher or student directed. We conclude that inquiry‐based learning is a necessary and complex interplay of teacher‐directed and student‐directed activities and that more research on the elements contributing to the kikan‐shido functions performed by teachers could help better identify and strengthen teacher practice for inquiry‐based learning.
Examination disclosure, issuance examination committee connections and accountants' IPO market share
Authors: Zhang Zhaoya , Wang Jenny Jing , Zhou Biao 
Published: July 2024

AbstractThis study examines the impact of an initial public offering (IPO) examination disclosure on accountants' IPO market share, using accounting firms undertaking A‐share approval system IPO audit projects from 2011 to 2021. We find that the IPO market share of accounting firms with Issuance Examination Committee Connections (IECC) decreases after the implementation of the issuance examination disclosure policy and that the market share decrease is more pronounced for low‐reputation accounting firms with IECC. This study reveals the impact of issuance review disclosures on the appointment of accountants by IPO firms. This study extends the research related to accountants' market share from the perspective of the impact of IPO examination disclosure on the IPO market share of IECC accountants.
A population pharmacokinetic model for sertraline in women during the perinatal period—A contribution from the ConcePTION project
Authors: Monfort Anaëlle , Cardoso Evelina , Eap Chin B. , Ansermot Nicolas , Crettol Severine , Fischer Fumeaux Céline J. , Graz Myriam Bickle , Harari Mathilde Morisod , Weisskopf Etienne , Gandia Peggy , Allegaert Karel , Annaert Pieter , Nordeng Hedvig , Hascoët Jean‐Michel , Claris Olivier , Epiney Manuella , Ferreira Ema , Leclair Grégoire , Csajka Chantal , Panchaud Alice , Guidi Monia ,   collaborators of the SSRI Breast Milk study
Published: July 2024

AbstractAimsSertraline is frequently prescribed for mental health conditions in both pregnant and breastfeeding women. According to the limited available data, only small amounts of sertraline are transferred into human milk, yet with a large amount of unexplained interindividual variability. This study aimed to develop a population pharmacokinetic (popPK) model to describe the pharmacokinetics of sertraline during the perinatal period and explain interindividual variability.MethodsPregnant women treated with sertraline were enrolled in the multicenter prospective cohort SSRI‐Breast Milk study. A popPK model for sertraline maternal plasma and breast milk concentrations was developed and allowed estimating the milk‐to‐plasma ratio (MPR). An additional fetal compartment allowed cord blood concentrations to be described. Several covariates were tested for significance. Ultimately, model‐based simulations allowed infant drug exposure through placenta and breast milk under various conditions to be predicted.ResultsThirty‐eight women treated with sertraline were included in the study and provided 89 maternal plasma, 29 cord blood and 107 breast milk samples. Sertraline clearance was reduced by 42% in CYP2C19 poor metabolizers compared to other phenotypes. Doubling milk fat content increased the MPR by 95%. Simulations suggested a median daily infant dosage of 6.9 μg kg−1 after a 50 mg maternal daily dose, representing 0.95% of the weight‐adjusted maternal dose. Median cord blood concentrations could range from 3.29 to 33.23 ng mL−1 after maternal daily doses between 25 and 150 mg.ConclusionsInfant exposure to sertraline, influenced by CYP2C19 phenotype and breast milk fat content, remains low, providing reassurance regarding the use of sertraline during pregnancy and breastfeeding.
Prospective study of urinary incontinence recovery following endoscopic enucleation of the prostate
Authors: Wu Shao‐Wei , Tseng Chi‐Shin , Yuan Lun‐Hsiang , Huang Yu‐Wen , Chen Yi‐Jhou , Kuo Ming‐Chieh , Chueh Jeff Shih‐Chieh , Huang Shi‐Wei 
Published: July 2024

ObjectiveTo investigate the clinical trajectories and identify risk factors linked to post‐enucleation urinary incontinence (UI).Patients and MethodsIn this prospective study (April 2020 to March 2022) at a single institution, 316 consecutive patients receiving endoscopic enucleation due to benign prostatic enlargement were included. Patient information and perioperative details were collected. Follow‐ups, from 1 to 6 months, assessed postoperative UI using International Consultation on Incontinence Questionnaire–Urinary Incontinence Short Form and a four‐item pad questionnaire, classified per International Continence Society definitions. Logistic regression analysed predictors at 1 week, while generalised estimating equation assessed risk factors from 1 to 3 months postoperatively.ResultsPatients with a median prostate volume of 57 mL underwent enucleation, with 22.5% experiencing postoperative UI at 1 week, 5.6% at 3 months, decreasing to 1.9% at 6 months. Multivariable analysis identified age (>80 years), specimen weight (>70 g), en bloc with anteroposterior dissection, and anal tone (Digital Rectal Examination Scoring System score <3) as potential factors influencing UI. Subgroup analysis revealed that specimen weight was associated with both continuous and stress UI. Anal tone was related to both other types and stress UI, while overactive bladder symptoms were associated with urge UI.ConclusionIn summary, our study elucidates transient risk factors contributing to temporary post‐enucleation UI after prostatectomy. Informed decisions and personalised interventions can effectively alleviate concerns regarding postoperative UI.
SCA44‐ and SCAR13‐associated GRM1 mutations affect metabotropic glutamate receptor 1 function through distinct mechanisms
Authors: Wang Yuyang , Muraleetharan Ashwin , Langiu Monica , Gregory Karen J. , Hellyer Shane D. 
Published: July 2024

Background and PurposeMetabotropic glutamate receptor 1 (mGlu1) is a promising therapeutic target for neurodegenerative CNS disorders including spinocerebellar ataxias (SCAs). Clinical reports have identified naturally‐occurring mGlu1 mutations in rare SCA subtypes and linked symptoms to mGlu1 mutations. However, how mutations alter mGlu1 function remains unknown, as does amenability of receptor function to pharmacological rescue. Here, we explored SCA‐associated mutation effects on mGlu1 cell surface expression, canonical signal transduction and allosteric ligand pharmacology.Experimental ApproachOrthosteric agonists, positive allosteric modulators (PAMs) and negative allosteric modulators (NAMs) were assessed at two functional endpoints (iCa2+ mobilisation and inositol 1‐phosphate [IP1] accumulation) in FlpIn Trex HEK293A cell lines expressing five mutant mGlu1 subtypes. Key pharmacological parameters including ligand potency, affinity and cooperativity were derived using operational models of agonism and allostery.Key ResultsmGlu1 mutants exhibited differential impacts on mGlu1 expression, with a C‐terminus truncation significantly reducing surface expression. Mutations differentially influenced orthosteric ligand affinity, efficacy and functional cooperativity between allosteric and orthosteric ligands. Loss‐of‐function mutations L454F and N885del reduced orthosteric affinity and efficacy, respectively. A gain‐of‐function Y792C mutant mGlu1 displayed enhanced constitutive activity in IP1 assays, which manifested as reduced orthosteric agonist activity. The mGlu1 PAMs restored glutamate potency in iCa2+ mobilisation for loss‐of‐function mutations and mGlu1 NAMs displayed enhanced inverse agonist activity at Y792C relative to wild‐type mGlu1.Conclusion and ImplicationsCollectively, these data highlight distinct mechanisms by which mGlu1 mutations affect receptor function and show allosteric modulators may present a therapeutic strategy to restore aberrant mGlu1 function in rare SCA subtypes.
Lianas associated with continued forest biomass losses following large‐scale disturbances
Authors: Mackintosh Emma J. , Waite Catherine E. , Putz Francis E. , Brennan Sophie , Pfeifer Marion , Marshall Andrew R. 
Published: July 2024

AbstractLianas are important to rainforest ecosystems but often impede tree growth and increase tree mortality and stem damage after disturbances that favor their growth. Understanding how lianas affect biomass recovery and rates of carbon sequestration following disturbance is therefore of crucial importance. In this study, we determine how a tropical forest recovers biomass following a large‐scale disturbance, and test how this varies with liana dominance and stem damage. We use remote sensing methods to develop a model, validated by field data from 40 20 × 20 m vegetation plots, to measure the change in tree aboveground biomass 8 years after Tropical Cyclone Yasi damaged logged forests in the Australian Wet Tropics. We related tree biomass changes to field measures of current liana dominance over trees, expressed as liana: tree basal area ratio, and assessed how these measures related to tree stem damage. Biomass declined in 34 of the 40 plots during the 8 years post‐disturbance, with loss rates and proportions of damaged tree stems increasing with the liana: tree ratio. From spatial upscaling, we found a net loss in biomass across the study landscape over the same period. Our results show that, following disturbances, lianas not only limit tree biomass recovery but also are associated with further biomass declines, most likely through their contribution to stem damage and delayed mortality. Furthermore, our finding of net biomass loss across the landscape since the cyclone shows that, post‐disturbance, rainforests can act as a carbon source with consequences for the global carbon sink.
Children as ‘becomings’—Mapping parental adultcentrism in Hungary
Authors: Németh Barbara , Sulyok Róza Sára , Szabó Brigitta , Miklósi Mónika 
Published: July 2024

AbstractAdultcentrism is the tendency of adults to view children from a biased perspective, hindering the recognition of children's competence and agency. It presents a challenge for parents, potentially influencing parenting practices and children's participation in decision‐making. Adultcentrism has received increasing attention in the literature, and with its recent operationalization, a new focus has emerged. However, adultcentrism has remained unexplored in Hungary. Using the Adultcentrism Scale, we aimed to conceptualize adultcentrism in this sociocultural context and validate the instrument in a different language, both for the first time. A cross‐sectional sample of 422 parents was surveyed online to analyse adultcentrism in Hungary and identify whether adult‐centric thinking is associated with less‐positive parenting behaviour. Our findings showed that extreme adult‐centric biases are rare among Hungarian parents and indicated that adult‐centric thinking has two major dimensions in our context. Firstly—and dominantly—adults tend to think about children as ‘becoming’ rather than ‘being’. Secondly, they tend to underestimate children's agency. The present conceptualization challenged the role of seeing children as incompetent in the construct. Adultcentrism indicated a weak positive association with parental perceptions of children's participation in decision‐making and positive parenting behaviours. However, it was not associated with negative behaviours, except for physical control. Our findings support the latest research that emphasizes that a certain level of adultcentrism is natural and presents thought‐provoking dilemmas regarding the understanding and measurement of adultcentrism in the Hungarian context. The study has implications for researchers analysing and theorizing this evolving construct and practitioners who want to improve the adult–child relationship.
Is there a conservation relationship between tourism, economic output, and forest areas?
Authors: Kocak Emrah , Cavusoglu Muhittin 
Published: July 2024

AbstractThis study employed advanced panel data analysis, accounting for cross‐sectional dependence and heterogeneity, to investigate the impact of tourism development and economic output on forest areas in major international tourist markets. The research was guided by forest transformation hypothesis (FTH). The study assessed the validity of FTH, examined the influence of tourism, and identified the income level at which a turning point occurs. The results revealed a heterogeneous impact of tourism on forested areas across major international tourist markets. Specifically, tourism development encouraged afforestation in Germany, Italy, Mexico, Spain, the United Kingdom, and the United States, but led to deforestation in China. In contrast, no significant relationship was observed between the tourism‐forest area nexus in Türkiye and Thailand. Additionally, the study provided evidence supporting FTH in the relationship between economic growth and forested areas in Italy, Spain, Türkiye, the United Kingdom, and the United States. Given these findings, the paper underscores the strong heterogeneity among the individual countries and their tourism, economic development, and forest areas. Consequently, country‐specific sustainable policies are advocated over generic approaches in the fight against deforestation.
The Impact of High‐standard Free Trade Areas on the Diversification of China's Export Products: Expanding Market or Intensifying Competition?
Authors: Fan Zhaobin , Bian Ruimin , Li Hui 
Published: July 2024

AbstractIn the context of China's efforts to establish a global network of free trade areas and diversify its export products, this study explores the impact of trade agreement depth on China's export diversification. Building upon a trade model with multiproduct firms, we discover that the effect of trade agreement depth on export diversification is multifaceted, depending on the relative magnitude of the “market expansion effect” and the “competition intensification effect.” Through empirical analysis of China's exports to 132 countries (or regions) from 2000 to 2015, we find that the deepening of trade agreements affected China's export diversification negatively. This negative correlation was predominantly due to the similarity in comparative advantages between China and its trade partners, leading to the “competition intensification effect” overshadowing the “market expansion effect.” We also note that “natural” agreements, when deepened, were more likely to affect China's export diversification adversely than their “non‐natural” counterparts. Moreover, as export diversification increased, the marginal impact of deepening trade agreements exhibited an inverted U‐shaped trajectory.
How Effective are Decentralized Anti‐poverty Programs?
Authors: Chen Shuai , Cheng Mingda , Tan‐Soo Jie‐Sheng 
Published: July 2024

AbstractThis study examines the effectiveness of China's National Poor Counties (NPC) program, a decentralized anti‐poverty initiative, by analyzing five rounds of individual‐level panel data from 1988 to 2008. The impact of two waves of the NPC program (1994 and 2001) is evaluated utilizing a panel fixed‐effects regression model. The results indicate substantial positive effects, with residents in NPC counties experiencing a 47 percent income increase, 3.1 percent higher employment rates, and a 5.7 percent rise in household expenditure from 1988 to 2008, in comparison with non‐NPC counties. Notably, the program benefited vulnerable populations, dispelling concerns about “elite capture.” The study also reveals that evolving policy focus has played a pivotal role in sustaining the effects of the program over time. The 1994 round prioritized low‐skilled employment, and the 2001 wave emphasized productivity enhancement through skills development. These findings highlight the continued efficacy of decentralized anti‐poverty efforts.
Exploring the gender gap in agricultural productivity: Evidence from Sri Lanka
Authors: Fukase Emiko , Kim Yeon Soo , Chiarella Cristina 
Published: July 2024

AbstractMotivationMen farmers typically achieve higher productivity than women farmers, a gender gap that reflects women's disadvantages in farming. Sri Lanka seems an exception, because women farmers achieve higher land productivity (gross value of output per hectare) than men farmers. That said, despite women's productivity advantage, men earn higher agricultural incomes.PurposeWe investigate the factors contributing to the unconditional agricultural productivity advantage of women farmers and the gender gap in agricultural earnings in favour of men in Sri Lanka.Approach and methodsUsing data from the nationally representative 2016 Sri Lanka Household Income and Expenditure Survey, we employ Oaxaca‐Blinder decomposition to analyse factors behind the gender disparities in agricultural productivity and earnings.FindingsThe leading factor contributing to higher female land productivity is the smaller plot size cultivated by women, reflecting an inverse relation between cultivated area and yield. The next most important factor is the gendered pattern of crop mix: women tend to cultivate high‐value export crops such as tea, while men are more likely to grow paddy — a less productive crop. When plot size and crop mix are controlled, men farmers achieve a conditional productivity advantage over women farmers. For crop earnings, men have both unconditional and conditional advantages, mainly due to their greater access to land and other inputs. While women's small plots have high yields, their size limits women's farm incomes.Policy implicationsPolicies to improve women's lagging access to land, inputs and other agricultural resources — often due to inherent gender bias — are needed to close the gender gap in agricultural income. Government policies favouring import‐competing commodities such as paddy, mainly through fertilizer subsidies, tend to benefit disproportionately men who are more likely to engage in paddy farming. Reallocating public spending on agriculture could enhance both efficiency and gender equality.
Changes in the treatment landscape of metastatic hormone‐sensitive prostate cancer following approval of upfront androgen receptor signaling inhibitors: A multicenter study
Authors: Urabe Fumihiko , Muramoto Katsuki , Yanagisawa Takafumi , Fukuokaya Wataru , Mori Keiichiro , Tashiro Kojiro , Katsumi Kota , Takahashi Hidetsugu , Yoshihara Kentaro , Miyajima Keiichiro , Imai Yu , Iwatani Kosuke , Kayano Sotaro , Igarashi Taro , Murakami Masaya , Tsuzuki Shunsuke , Shimomura Tatsuya , Yamada Hiroki , Miki Jun , Kimura Takahiro ,   JIKEI‐YAYOI Collaborative Group
Published: July 2024

BackgroundA multicenter database was utilized to examine the current treatment landscape and clinical outcomes among patients with metastatic hormone‐sensitive prostate cancer (mHSPC) following approval of upfront androgen receptor signaling inhibitors (ARSIs).MethodsWe retrospectively analyzed patients with mHSPC who commenced treatment between February 2018 and June 2023. The Kaplan–Meier method was used to assess oncological outcomes, including time to castration‐resistant prostate cancer (CRPC), progression‐free survival 2 (PFS2, duration from initial treatment to tumor progression during second‐line treatment), cancer‐specific survival (CSS), and overall survival (OS). Cox regression analyses were performed to determine the impact of treatment choices on oncological outcomes. In addition, the incidence rate of adverse events was assessed.ResultsIn total, 829 patients were analyzed; 42.5% received ARSIs with androgen deprivation therapy (ADT), 44.0% received combined androgen blockade (CAB), and 13.5% received ADT alone. Kaplan–Meier curves and multivariate Cox regression analyses indicated higher rates of CRPC and shorter PFS2 in patients treated with CAB versus ARSIs with ADT. By contrast, CSS and OS were not significantly different between the ARSI with ADT group and the CAB group. Grades 3–4 adverse events occurred in 1.9% of patients receiving CAB and 6.0% of those receiving ARSIs with ADT.ConclusionsInitial treatment with ARSIs in combination with ADT resulted in a longer time to CRPC and longer PFS2 compared to CAB. Although CAB and ADT alone were associated with fewer adverse events, ARSIs with ADT should be considered a first‐line treatment option given its superior oncological outcomes.