bluuebunny/crossref_metadata_2025_split huggingface dataset:
Associations of maternal lifestyle factors with inadequate pregnancy weight gain: findings from the baseline data of the LIMIT prospective cohort study
Authors: El Masri Dana , Alemayohu Mulubirhan Assefa , Loperfido Federica , Bianco Irene , Ferrara Chiara , Cerbo Rosa Maria , Ghirardello Stefano , Monti Maria Cristina , Maccarini Beatrice , Sottotetti Francesca , Civardi Elisa , Garofoli Francesca , Angelini Micol , Cena Hellas , De Giuseppe Rachele 
Published: August 2024

Abstract
Background/objectives
Gestational Weight Gain (GWG) impacts maternal and fetal health; deviations from optimal ranges pose health risks. Maternal lifestyle before and during pregnancy strongly influences GWG. This study explores factors linked to inadequate GWG, focusing on Mediterranean Diet (MD) adherence and specific food consumption.

Subjects/methods
178 pregnant women were enrolled at Fondazione IRCCS Policlinico San Matteo (Pavia) during pre-hospital care before birth meeting inclusion/exclusion criteria. Sociodemographic data, pre-pregnancy BMI, GWG, MD adherence, physical activity (PA) levels, and smoking habits were retrospectively collected. Validated questionnaires adapted for the target group, assessed MD adherence and PA level. Participants were classified into adequate (AGWG) and inadequate GWG groups following IOM guidelines.

Results
Among 200 pregnant women (aged 30–36), 37.1% experienced low GWG and 24.1% excessive GWG. Our study revealed a significant association between inadequate GWG and educational level (P = 0.011); pre-pregnancy BMI (P = 0.005); MD adherence (P = 0.008), and daily average consumption of vegetables (P < 0.001). Our results also showed that a lower risk of EGWG vs. AGWG was associated with daily average consumption of vegetables (RRR = 0.279, P = 0.004), while a higher risk of EGWG vs. AGWG was associated with high daily meat product consumption (> 1.5 portions/day) (RRR = 7.83, P = 0.03). Conclusion. These findings emphasize the importance of promoting lifestyle changes before and during pregnancy to tackle the increasing incidence of inadequate GWG and improve the health outcomes of both mother and child.
Identifying crystal nucleation mechanisms in a synthetic trachybasalt: a multimodal approach
Authors: Peres Stefano , Griffiths Thomas A. , Colle Fabio , Lelarge Stefano Iannini , Masotta Matteo , Pontesilli Alessio , Mancini Lucia , Abart Rainer 
Published: August 2024

AbstractTo develop new criteria to distinguish different crystal nucleation mechanisms in silicate melts, we performed crystallization experiments using a synthetic hydrous (2 wt% H2O) trachybasalt and combined three-dimensional information from synchrotron X-ray computed microtomography with two-dimensional mapping of crystallographic orientation relationships (CORs) using electron backscatter diffraction. Crystallization experiments were performed at 400 MPa by cooling the melt from 1300 °C to resting temperatures of 1150 and 1100 °C and maintaining isothermal conditions for 30 min and 8 h. Three distinct titanomagnetite (Tmt) populations formed: (1) skeletal crystals, isolated or partially embedded in clinopyroxene (Cpx); (2) anhedral crystals, always attached to Cpx; (3) flattened needle-shaped crystals, embedded in Cpx. These morphologically different Tmt populations formed in response to one cooling event, with varying nucleation mechanisms and at different undercooling conditions. The clustered three-dimensional distribution of population 2 and 3 Tmt grains and the high proportion of Tmt-Cpx interfaces sharing CORs indicate that these Tmt grains heterogeneously nucleated on Cpx. The near-random three-dimensional distribution of (often isolated) population 1 Tmt grains, together with the low proportion of Tmt-Cpx interfaces sharing CORs, imply their isolated, possibly homogeneous nucleation, potentially followed by heterogeneous nucleation of Cpx on population 1 Tmt. Heterogeneous nucleation in slightly to moderately undercooled magmas should affect the sequence of crystallization as well as morphology and clustering of crystals, which may actively contribute to the variation of rheological parameters like viscosity. Finally, observed intra- and inter-sample variations in Tmt-Cpx COR frequencies indicate the potential for this parameter to record further petrological information.
Peritoneal infection after colorectal cancer surgery induces substantial alterations in postoperative protein levels: an exploratory study
Authors: Grahn Oskar , Holmgren Klas , Jonsson Pär , Borgmästars Emmy , Lundin Christina , Sund Malin , Rutegård Martin 
Published: August 2024

Abstract
Purpose
Peritoneal infection, due to anastomotic leakage, after resection for colorectal cancer have been shown to associate with increased cancer recurrence and mortality, as well as cardiovascsular morbidity. Alterations in circulating protein levels could help shed light on the underlying mechanisms, prompting this exploratory study of 64 patients operated for colorectal cancer with anastomosis.

Methods
Thirty-two cases who suffered a postoperative peritoneal infection were matched with 32 controls who had a complication-free postoperative stay. Proteins in serum samples at their first postoperative visit and at one year after surgery were analysed using proximity extension assays and enzyme-linked immunosorbent assays. Multivariate projection methods, adjusted for multiple testing, were used to compare levels between groups, and enrichment and network analyses were performed.

Results
Seventy-seven proteins, out of 270 tested, were differentially expressed at a median sampling time of 41 days postoperatively. These proteins were all normalised one year after surgery. Many of the differentially expressed top hub proteins have known involvement in cancer progression, survival, invasiveness and metastasis. Over-represented pathways were related to cardiomyopathy, cell-adhesion, extracellular matrix, phosphatidylinositol-3-kinase/Akt (PI3K-Akt) and transforming growth factor beta (TGF-β) signaling.

Conclusion
These affected proteins and pathways could provide clues as to why patients with peritoneal infection might suffer increased cancer recurrence, mortality and cardiovascular morbidity.
Exploring the role of Life Essential 8 in patients diagnosed with systemic lupus erythematosus and rheumatoid arthritis
Authors: Wang Xiaoying , Bai Yintao , Zou Xiaolan , He Xincheng , Xie Xiaoxiang , Ru Jinli 
Published: August 2024

Abstract
Objective
To investigate the distribution of the Life Essential 8 (LE8) score among adult patients with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) and explore its association with disease activity.

Methods
A cross-sectional study was conducted to select adult patients with SLE and RA who were treated in the general department of the Second Hospital of Shanxi Medical University between May 2022 and September 2023. Through questionnaires, patients’ diet, sleep, smoking habits, and daily exercise were evaluated. Additionally, blood glucose, blood lipids, inflammatory markers, and other relevant data were collected to assess the LE8 levels of the participants. The data was analyzed using SPSS 26.0. Both univariate and ordered multivariate logistic regression were employed to explore the distribution and influencing factors of the LE8 score among the patients.

Results
A total of 43 adult cases of SLE and 55 RA cases were studied, encompassing 11 males and 87 females with a mean age of 49.12 ± 15.86 years. The LE8 score averaged at 68.82 ± 12.29; specifically, the LE8 behavior score was 60.91 ± 17.78, and the LE8 factor score was 77.05 ± 14.30. The disease activity scores of both conditions showed a negative correlation with LE8. As DAS28 (r =  − 0.96, P < 0.05) and SLEDAI (r =  − 0.807, P < 0.05) scores increased, the LE8 score decreased. A low SLEDAI score serves as a protective factor for LE8 (OR (95% CI) = 0.07 (0.01, 0.37), P = 0.02). Furthermore, among patients with RA (OR (95% CI) = 0.03 (0.00, 0.22), P = 0.001) and SLE (OR (95% CI) = 0.06 (0.01, 0.35), P = 0.002), individuals boasting higher LE8 scores exhibit a reduced 10-year cardiovascular risk.

Conclusions
Patients suffering from RA and SLE often exhibit low LE8 scores, reflecting a concerning cardiovascular health status—particularly in cases of high disease activity. Hence, it is imperative to prioritize the cardiovascular well-being of rheumatic patients.

Key Points• Research has revealed that individuals suffering from RA and SLE exhibit lower LE8 scores, potentially attributed to alterations in disease activity• In this study, no statistically significant associations were discerned between inflammatory markers and LE8 scores among patients with RA and SLE. Nevertheless, among SLE patients specifically, a notable correlation was observed between ds-DNA levels and LE8 factor scores.• Enhancing the compliance rate for the LE8 target among patients with RA and SLE could potentially mitigate the cardiovascular risk associated with these conditions.
Acute impacts of invasive toads on the population demography of a native predator in tropical Australia
Authors: Ward-Fear G. , Brown G. P. , Shine R. 
Published: August 2024

AbstractIf an animal’s size, age and/or sex influence its vulnerability to an invasive species, the arrival of such an invader can cause rapid changes in the population demography of an affected species. We studied free-ranging varanid lizards (Yellow-spotted monitors, Varanus panoptes) at a site in tropical Australia during the influx of fatally toxic cane toads, Rhinella marina. Mortality was inferred from shifts in population structure, as well as the survival rates (time to death) of 107 radio-tracked lizards. Of 57 deaths whose cause was unambiguous, 32 were due to fatal poisoning by ingesting a cane toad; the other 25 lizards were consumed by pythons. Size and age structure shifted between years, such that the population post-invasion was dominated by smaller, younger lizards, and by females rather than males. Radiotelemetric monitoring confirmed that survival rates were reduced more in males than in females in the post-toad year, with males most at risk late in the dry-season, when food was scarce and females were nesting rather than foraging. Pythons disproportionately consumed larger female lizards during the nesting season. Toad-induced poisoning of adult male varanids (which are larger and bolder than females) likely produced a population that was more resilient to toad impact, but less easily surveyed by conventional techniques.
Psychological factors impacts on carsharing use
Authors: Abouelela Mohamed , Al Haddad Christelle , Antoniou Constantinos 
Published: August 2024

AbstractCarsharing services have a significant potential for improving urban mobility by increasing the independence and freedom of travel and reducing traffic externalities. Although carsharing has been used for over a decade, several aspects need further investigation, such as the impact of user’s psychological factors on service use, as well as the factors impacting users’ choices between different carsharing operators, in particular their preferences for different payment schemes, and their perceptions of the operators’ application rating. Accordingly, four hybrid choice models (HCM) were estimated to investigate factors impacting (i) the knowledge about carsharing services, (ii) carsharing adoption, (iii) the shift from other modes to carsharing, (iv) the choice between carsharing operators with different payment schemes, using a large survey sample (N = 1044 responses 9469 SP observation) from Munich, Germany. The models showed the significance of sociodemographics, such as income level, education level, household size, employment status, ownership of a bike, access to a car, the availability of a driving license, and public transport subscription-based tickets on the carsharing use directly and indirectly, and four psychological factors encompassing different personality traits (i.e., adventurous), travel behavior, and attitudes were found to be significant in the various models; the latter covered service-related attitudes (perceived carsharing app importance) and travel behavior attitudes or profiles (frequent public transport user and frequent shared micromobility user). This research raises questions regarding the inequitable use of carsharing, the impacts of mobile applications on using the service, and the potential of integrating carsharing in mobility as a Service platforms to increase the potential for multimodality.
HybGrip: a synergistic hybrid gripper for enhanced robotic surgical instrument grasping
Authors: Badilla-Solórzano Jorge , Ihler Sontje , Seel Thomas 
Published: August 2024

Abstract
Purpose
A fundamental task of a robotic scrub nurse is handling surgical instruments. Thus, a gripper capable of consistently grasping a wide variety of tools is essential. We introduce a novel gripper that combines granular jamming and pinching technologies to achieve a synergistic improvement in surgical instrument grasping.

Methods
A reliable hybrid gripper is constructed by integrating a pinching mechanism and a standard granular jamming gripper, achieving enhanced granular interlocking. For our experiments, our prototype is affixed to the end-effector of a collaborative robot. A novel grasping strategy is proposed and utilized to evaluate the robustness and performance of our prototype on 18 different surgical tools with diverse geometries.

Results
It is demonstrated that the integration of the pinching mechanism significantly enhances grasping performance compared with standard granular jamming grippers, with a success rate above 98%. It is shown that with the combined use of our gripper with an underlying grid, i.e., a complementary device placed beneath the instruments, robustness and performance are further enhanced.

Conclusion
Our prototype’s performance in surgical instrument grasping stands on par with, if not surpasses, that of comparable contemporary studies, ensuring its competitiveness. Our gripper proves to be robust, cost-effective, and simple, requiring no instrument-specific grasping strategies. Future research will focus on addressing the sterilizability of our prototype and assessing the viability of the introduced grid for intra-operative use.
Metaheuristics for Solving Global and Engineering Optimization Problems: Review, Applications, Open Issues and Challenges
Authors: Houssein Essam H. , Saeed Mahmoud Khalaf , Hu Gang , Al-Sayed Mustafa M. 
Published: August 2024

AbstractThe greatest and fastest advances in the computing world today require researchers to develop new problem-solving techniques capable of providing an optimal global solution considering a set of aspects and restrictions. Due to the superiority of the metaheuristic Algorithms (MAs) in solving different classes of problems and providing promising results, MAs need to be studied. Numerous studies of MAs algorithms in different fields exist, but in this study, a comprehensive review of MAs, its nature, types, applications, and open issues are introduced in detail. Specifically, we introduce the metaheuristics' advantages over other techniques. To obtain an entire view about MAs, different classifications based on different aspects (i.e., inspiration source, number of search agents, the updating mechanisms followed by search agents in updating their positions, and the number of primary parameters of the algorithms) are presented in detail, along with the optimization problems including both structure and different types. The application area occupies a lot of research, so in this study, the most widely used applications of MAs are presented. Finally, a great effort of this research is directed to discuss the different open issues and challenges of MAs, which help upcoming researchers to know the future directions of this active field. Overall, this study helps existing researchers understand the basic information of the metaheuristic field in addition to directing newcomers to the active areas and problems that need to be addressed in the future.
Lacticaseibacillus casei as Anti-blowing Agents: Impact on the Evolution of Ripening and Sensory Profile of Montasio Cheese
Authors: Trevisiol Francesca , Renoldi Niccolò , Rossi Anna , Di Filippo Giulia , Marino Marilena , Innocente Nadia 
Published: August 2024

Abstract
Recently, the Lacticaseibacillus casei group strains have been gaining growing interest due to their potential to be used as secondary adjunct cultures in cheese. This work aimed to test autochthonous Lb. casei strains as anti-blowing agents and to evaluate their impact on the evolution of the ripening and the sensory profile of Montasio cheese. The cheesemaking trial included a control production without lysozyme (C1), a control with lysozyme (C2), and four experimental productions, each containing a different pool of autochthonous Lb. casei strains (EX1-4). Samples were taken during ripening, and physicochemical, microbiological, and sensory analyses were carried out. Lb. casei counts indicate that the selected strains survived the cheesemaking and maintained their viability of about 9 log cfu g−1 at the end of the ripening. Only EX3 showed a significant slowdown of the proteolytic index compared to controls over time. Furthermore, from the principal component analysis, it emerged that at the end of the 120-day-long ripening, C2 and the experimental samples were characterized by similar profiles of volatile compounds. The late-blowing defect (LBD) was observed exclusively in C1, whereas it was not detected in the control sample with lysozyme or in any experimental samples. These findings not only confirmed the efficacy of lysozyme in preventing LBD but also supported the effectiveness of the selected Lb. casei strains as anti-blowing agents with the ability to contribute to the final volatile profile without compromising the typicality of the product.
Self-Monitoring of Weight as a Weight Loss Strategy: A Systematic Review
Authors: Hallock Rajiev , Ufholz Kelsey , Patel Niki 
Published: August 2024

Abstract
Purpose of Review
Gauge the effectiveness of self-monitoring of weight for weight loss.

Recent Findings
Daily self-monitoring of weight results in increased weight loss, or improved weight maintenance as compared to infrequent or no self-monitoring of weight. Self-weighing is most effective when tied with other behavioral interventions including tracking caloric intake and physical activity tracking.

Summary
Self-monitoring of weight is an effective behavioral weight loss intervention which allows patients to track their progress, but also allows them to connect daily life activities with their weight, fostering real-time feedback that allows them to make more informed and personalized decisions related to dietary choices, physical activity, and lifestyle medicine.
Extraction of Bioactive Compounds from Rubus Idaeus Bioresidues: A Full Screening on Phenolic Composition and Bioactive Potential
Authors: Plasencia Paula , Finimundy Tiane C. , Carocho Márcio , Calhelha Ricardo C. , Añibarro-Ortega Mikel , Pires Tânia C.S.P. , Barreiro Filomena , Garcia Pablo A. , Barros Lillian , Heleno Sandrina A. 
Published: August 2024

Abstract

Purpose

Rubus idaeus cultivation has boosted productivity due to its high nutritional value. In consequence, waste production increased. The discarded biomass, including leaves and aerial components, can be transformed into valuable functional ingredients for industrial applications, such as cosmetics. Studying their bioactivity potential is highly relevant.

Methods
According to the present idea, the research involved producing extracts from raspberry plant branches and leaves by employing four different techniques: aqueous decoction, aqueous infusion, hydroethanolic maceration, and ultrasound-assisted extraction (UAE). Subsequently, these compounds were screened for their bioactive potential, including antioxidant, antibacterial, anti-inflammatory, and cytotoxic properties.

Results
The ultrasound-assisted extraction produced extracts rich in phenolic compounds, whereas the infusion and maceration methods resulted in higher flavonol contents. Among the identified phenolic compounds, hydrolyzable tannins, particularly galloyl-bis-HHDP-glucose, were the most dominant ones. Regarding antioxidant potential, the decoction extract was the strongest, while the infusion showed the greatest potential for inhibiting lipid peroxidation. The UAE extract was found to be highly effective as an antibacterial agent. Both infusion and UAE extracts demonstrated the highest anti-inflammatory potential.

Conclusion
The combination of these results highlights the sample’s bioactive potential and the importance of exploiting bioresidues as unique, sustainable candidates for industrial applications.
Improved Atmosphere‐Ocean Coupled Simulation by Parameterizing Sub‐Diurnal Scale Air‐Sea Interactions
Authors: Wang K. , Zhang S. , Jin Y. , Zhu C. , Song Z. , Gao Y. , Yang G. 
Published: August 2024

AbstractThe atmosphere‐ocean is a highly coupled system with significant diurnal and hourly variations. However, current coupled models usually lack sub‐diurnal scale processes at the air‐sea interface due to the finite vertical resolution for ocean discretization. Previous modeling studies showed that sub‐diurnal scale air‐sea interaction processes are important for ocean mixing. Here, by designing an integrated sub‐diurnal parameterization (ISDP) scheme which combines different temperature profiling functions, we stress sub‐diurnal air‐sea interactions to better represent the local ocean mixing. This scheme has been implemented into two coupled models which contributed to the Climate Model Intercomparison Project (CMIP), referenced by the Intergovernmental Panel on Climate Change—Community Earth System Model and Coupled Model version 2. The results show that the ISDP scheme improves model simulations with better climatology and more realistic spectra, especially in the tropics and North Pacific Ocean. With the scheme, the tropical cold tongue bias is significantly relaxed by reducing the overestimation of ocean upper mixing, and the cold bias of North Pacific Ocean is reduced due to the improvement on currents and net heat fluxes. Our scheme may help better the simulation and prediction skills of coupled models when their horizontal resolution becomes fine but vertical resolution remains relatively coarse as it describes high‐frequency air‐sea interactions more realistically.
Advancing Parsimonious Deep Learning Weather Prediction Using the HEALPix Mesh
Authors: Karlbauer Matthias , Cresswell‐Clay Nathaniel , Durran Dale R. , Moreno Raul A. , Kurth Thorsten , Bonev Boris , Brenowitz Noah , Butz Martin V. 
Published: August 2024

AbstractWe present a parsimonious deep learning weather prediction model to forecast seven atmospheric variables with 3‐hr time resolution for up to 1‐year lead times on a 110‐km global mesh using the Hierarchical Equal Area isoLatitude Pixelization (HEALPix). In comparison to state‐of‐the‐art (SOTA) machine learning (ML) weather forecast models, such as Pangu‐Weather and GraphCast, our DLWP‐HPX model uses coarser resolution and far fewer prognostic variables. Yet, at 1‐week lead times, its skill is only about 1 day behind both SOTA ML forecast models and the SOTA numerical weather prediction model from the European Center for Medium‐Range Weather Forecasts. We report several improvements in model design, including switching from the cubed sphere to the HEALPix mesh, inverting the channel depth of the U‐Net, and introducing gated recurrent units (GRU) on each level of the U‐Net hierarchy. The consistent east‐west orientation of all cells on the HEALPix mesh facilitates the development of location‐invariant convolution kernels that successfully propagate weather patterns across the globe without requiring separate kernels for the polar and equatorial faces of the cube sphere. Without any loss of spectral power after the first 2 days, the model can be unrolled autoregressively for hundreds of steps into the future to generate realistic states of the atmosphere that respect seasonal trends, as showcased in 1‐year simulations.