bluuebunny/crossref_metadata_2025_split huggingface dataset:
BAZ1B is dispensable for H2AX phosphorylation on Tyrosine 142 during spermatogenesis
Authors: Broering Tyler J. , Wang Yuan-Liang , Pandey Ram Naresh , Hegde Rashmi S. , Wang Shao-Chun , Namekawa Satoshi H. 
Published: May 2015

ABSTRACT
Meiosis is precisely regulated by the factors involved in DNA damage response in somatic cells. Among them, phosphorylation of H2AX on Serine 139 (γH2AX) is an essential signal for the silencing of unsynapsed sex chromosomes during male meiosis. However, it remains unknown how adjacent H2AX phosphorylation on Tyrosine 142 (pTyr142) is regulated in meiosis. Here we investigate the meiotic functions of BAZ1B (WSTF), the only known Tyr142 kinase in somatic cells, using mice possessing a conditional deletion of BAZ1B. Although BAZ1B deletion causes ectopic γH2AX signals on synapsed autosomes during the early pachytene stage, BAZ1B is dispensable for fertility and critical events during spermatogenesis. BAZ1B deletion does not alter events on unsynapsed axes and pericentric heterochromatin formation. Furthermore, BAZ1B is dispensable for localization of the ATP-dependent chromatin remodeling protein SMARCA5 (SNF2h) during spermatogenesis despite the complex formation between BAZ1B and SMARCA5, known as the WICH complex, in somatic cells. Notably, pTyr142 is regulated independently of BAZ1B and is dephosphorylated on the sex chromosomes during meiosis in contrast with the presence of adjacent γH2AX. Dephosphorylation of pTyr142 is regulated by MDC1, a binding partner of γH2AX. These results reveal the distinct regulation of two adjacent phosphorylation sites of H2AX during meiosis, and suggest that another kinase mediates Tyr142 phosphorylation.
The insulator protein CTCF regulatesDrosophilasteroidogenesis
Authors: Fresán Ujué , Cuartero Sergi , O'Connor Michael B. , Espinàs M. Lluisa 
Published: May 2015

ABSTRACTThe steroid hormone ecdysone is a central regulator of insect development. In this report we show that CTCF expression in the prothoracic gland is required for full transcriptional activation of the Halloween genes spookier, shadow and noppera-bo, which encode ecdysone biosynthetic enzymes, and for proper timing of ecdysone-responsive gene expression. Loss of CTCF results in delayed and less synchronized larval development that can only be rescued by feeding larvae with both, the steroid hormone 20-hydroxyecdysone and cholesterol. Moreover, CTCF-knockdown in prothoracic gland cells leads to increased lipid accumulation. In conclusion, the insulator protein CTCF is required for Halloween gene expression and cholesterol homeostasis in ecdysone-producing cells controlling steroidogenesis.
Unusual Tautomeric Energetics in 4n Azaheterocycles
Authors: Hatanaka Masashi 
Published: May 2015

Abstract
Unusual imino preference in 4n azaheterocycles is theoretically analyzed. It is attributed to less topological charge stability of the amino forms due to antisymmetric nonbonding molecular orbitals. The theory is applicable for designing stable imino species. The same analysis is also applicable for hydroxyl/oxo tautomerism, and results in very stable lactams.
Development of a Photoresponsive Organic–Inorganic Hybrid Magnet: Layered Cobalt Hydroxides Intercalated with Spiropyran Anions
Authors: Tanaka Naru , Okazawa Atsushi , Sugahara Akira , Kojima Norimichi 
Published: May 2015

Abstract
To develop an organic–inorganic hybrid photomagnet, we performed the intercalation of sulfonate-substituted spiropyran anions into layered cobalt hydroxides, obtaining the photoresponsive compound, Co(OH)1.84(nSPSO3)0.16·0.8H2O (CoLHSP; nSPSO3: 1′,3′,3′-trimethyl-6-nitrospiro[2H-1-benzopyran-2,2′-indoline]-5′-sulfonate). After UV irradiation (313 nm), the optical and magnetic properties of CoLHSP clearly changed. A new band emerged in the absorption spectrum at 564 nm, corresponding to the π–π* transition in the open form of nSPSO3. Moreover, the photoisomerization of nSPSO3 induced a new ferrimagnetic phase transition at 10 K in the temperature dependence of DC and AC magnetic susceptibilities in addition to the ferrimagnetic phase transition at 15 K for the unirradiated sample. Analyzing the magnetic measurements before and after UV irradiation, we estimated the phototransformation ratio of the magnetic phase in CoLHSP at approximately 40%.
Luminescence of Sn2+ Center in ZnO–B2O3 Glasses Melted in Air and Ar Conditions
Authors: Masai Hirokazu , Suzuki Yuto , Yanagida Takayuki , Mibu Ko 
Published: May 2015

Abstract
The authors report on luminescence of SnO-doped 60ZnO–40B2O3 (SZB) glasses melted in air and Ar atmosphere. In photoluminescence (PL), excitation spectra consist of two excitation bands, and the lower excitation band, emerging at lower energy with increasing amount of SnO, affects the optical absorption edge. The present SZB glasses can exhibit light emission by irradiation of near UV light, which is different from the zinc phosphate glass system. X-ray induced scintillation spectra indicate that concentration of Sn2+ mainly affects the intensity. 119Sn Mössbauer spectra show that a certain amount of Sn2+ centers in the SZB glass was oxidized to Sn4+ even when melted under the inert atmosphere, which is one of the reasons for the low PL quantum efficiencies, approximately 60%. The 119Sn Mössbauer spectra also suggest site dispersion of Sn2+ centers, whose local coordination states affect the optical absorption and luminescent properties.
Structural Formation of Dendritic Polymer Brushes: Analysis Using an Explicit Solvent Model
Authors: Terao Takamichi 
Published: May 2015

Abstract
Dendritic brushes, which provide higher stability against the aggregation of colloidal suspensions, were investigated using multicolor domain decomposition Monte Carlo simulations. Solvent molecules were explicitly considered, and the profiles of the monomer density and perimeter density distributions were calculated. The results show that the power-law dependence on grafting density depends weakly on the spacer length, the distance between neighboring branch points in dendrons. No apparent evidence was found for backfolding in the dendritic polymer brushes.
Mediatized solidarity, governmental support and metacommunicational narratives: The War on Gaza in leftist Latin American media
Authors: Bacallao-Pino Lázaro M. 
Published: May 2015

Abstract
This article aims to analyse the media discourses about the War on Gaza, a relevant topic in the case of public media associated with self-proclaimed left governments. The study encompasses three cases of public Latin American media: (1) Granma, the official journal of the Cuban Communist Party; (2) Telesur, a pan-Latin American television network headquartered in Caracas; and (3) Andes, a news agency created by the Ecuadorian government. Three main themes were analysed: (1) the construction of the good/bad narrative tension; (2) the representations of solidarity and governmental positions; and (3) the media discourses on (other) media discourses about the war. The findings indicate that, in the case of public media linked to these kinds of left-wing governments, the narratives regarding the war are in line with the official positions, underlining its readings on the tension between good and bad sides, reporting its statements and using a metacommunicational discourse as part of their argumentative strategy.
Rhetorical use of fear in presidential speeches: The War on Terror discourse
Authors: Goussios Charalampos , Aspriadis Neofytos , Tsirimiagou Zoi , Dogani Myrsini 
Published: May 2015

Abstract
This article explores the rhetorical use of fear in presidential speeches and its spillover to the media in order to achieve political and public consensus during a crisis situation. Fear is the primal emotion that people face under the recognition of an actual or an imaginary threat or danger. Based on that existential aspect, fear is also recognizable and identifiable rhetorical schema, applicable in the Mass Media/ Press. Strategic Communication uses this schema in its narrations and then diffuses it over in the Mass Media. Analysing that constructed fear we can extrapolate conclusions about the strategic planning of the political actors. In our case, we attempt to come to conclusions about the interconnection of the Rhetoric of Fear and the rhetorical construction of the ‘Rally around the Flag effect’ in the US Press. The analysis focuses on presidential rhetoric in the United States in the aftermath of 9/11 and the construction of the ‘War on Terror’ discourse. Using qualitative content and discourse analysis methodology, this article reveals that the rally around the flag effect has been mobilized rhetorically through the strategic use of fear that had been employed by the media and affected public opinion. The use of fear in President Bush’s rhetoric and its repetition by the governmental political elite influenced the opposition. The consensus of the political elite spilled over to the media and dominated the news, which reproduced the frames and the constructed fear arguments, providing a specific political reality for the public.
Parental mediation of adolescents’ Internet use in Jordan
Authors: Darweesh Abd El-Reheem A. S. , Mahmoud Abd El-Basit A. H. 
Published: May 2015

Abstract
While most previous studies on the internet use of Arab adolescants focused on examining the uses, benefits and risks of their online activities, less is known about the effects of parental mediation of adolescent internet use in the Arab world. This study attempts to explore the effects of parental mediation strategies on adolescent internet use and the exposure of Arab adolescants to online risks, as well as examining the influence of demographic variables on these strategies. A survey was conducted of 400 Jordanian preparatory and secondary school students, from 7 to 12 grade. The study revealed that males are more vulnerable to exposure to online risks. The educational level of the mother significantly affects the instructive mediation and exposure to online risks, while the fathers’ educational level has a significant effect on co-use mediation. The study also pointed out that there was no significant effect regarding gender on restrictive and instructive mediation.
Journalists’ views on the British coverage of Turkey’s EU bid and the clash of civilizations thesis
Authors: Paksoy Alaaddin F. 
Published: May 2015

Abstract
Turkey’s bid to join the European Union (EU) and the surrounding discussions in European countries’ national media have been receiving increasing interest since Turkey became an official EU membership candidate in 1999. However, almost all academic work concerning the topic examines only the media coverage. In contrast, this article looks at journalists’ views on the media content about Turkey, and also discusses the clash of civilizations thesis as a frame to understand the media discourse. Twenty-one journalists who work or had worked in various British media outlets participated in semi-structured interview sessions. The data was conceptualized and categorized with the help of qualitative analysis software NVivo. Findings are presented through two main sections: Journalists’ views on the decrease in Turkey–EU relations’ popularity in the British media and the changes in the content; and the clash of civilizations thesis in the context of Turkey’s EU bid. Journalists’ views on the coverage reveal that their approach to Turkey’s EU bid is in line with the general view of the British media. In addition, the findings show that the clash of civilizations paradigm is used as a tool for British politicians and the British media to expose their support for Turkey’s EU bid.
Banal balance, selective identification and factual omissions: The New York Times coverage of the 2014 War in Gaza
Authors: Artz Lee 
Published: May 2015

Abstract
This article employs the lens of media framing to investigate the editorial choices by the New York Times in covering the summer 2014 bombing and invasion of Gaza. Using an extended content analysis of front-page stories published by the New York Times from 8 July when the assault began through 26 August when a semi-stable cease fire was announced, primary explanatory frames, preferred sources and selective evaluations of events are identified. The findings suggest that a ‘both sides’ narrative, selective identification, and legitimation of sources and omissions of significant contextual facts provided readers, with singular diagnoses favouring acceptance and tolerance of Israeli actions with corollary condemnations of Palestinian actions. References from the United Nations and alternative news sources indicate that other evidence and frames would hold Israel guilty of war crimes and encourage increased support for ending the occupation.
Landscape desıgn project of the inner courtyard of the Laodikeia excavatıon house<p>Laodikeia kazı evi iç avlu peyzaj tasarım projesi
Authors: Özdemir Ayşe , Çetinkaya Elif 
Published: May 2015

<p>Laodikeia Ancient City, (that) is a focal point at spatial and functional identity of Denizli City, is a significant historical site that was selected into Temporary List of World Culture Heritage by UNESCO at 2013. For the purpose of Laodikeia Ancient City’s culture heritage of researching, to documented, to store, protecting and leaving to the next generations, restoration and conservation studies are executed along the whole year at Laodikeia Ancient City. Increasing productivity of these considerable works that is beneficial to world culture heritage is too important for Denizli and our country. Excavation house that was build for requirement entirely, has a courtyard where technique staff exists different career group can use on break time and can spend social time. The main theme of the article is the landscape design project of the Laodikeia antique site excavation house and its planning-design and application phases.</p><p>In this context, excavation house landscape design project was developed due to the aesthetical and fuctional uses as well as the basic needs of the users (such as working, resting etc.) regarding landscape design criteria supplying harmony between nature and built environment.</p><p> </p><p><strong>Özet</strong></p><p>Denizli Kenti’nin mekansal ve işlevsel kimliği açısından odak noktası olan Laodikeia Antik Kenti, 2013 yılında UNESCO tarafından Dünya Kültür Mirası Geçici Listesi'ne alınmış önemli bir ören yeridir. Bu açıdan bakılırsa, Laodikeia Antik Kentinin araştırılması, belgelenmesi, arşivlenmesine yönelik çalışmalar, kültürel miras kaynaklarının gelecek kuşaklara aktarılması açısından son derece önemlidir. Dünya kültür mirasına büyük katkıları olan bu tür çalışmaların verimli kılınması, Denizli ve ülkemiz için büyük önem taşımaktadır. Bu araştırmanın ana teması; Laodikeia Antik Kenti’ndeki tamamen kullanıcı odaklı ihtiyaç programına yönelik olarak yapılan kazı evi, burada çalışan çeşitli meslek gruplarından oluşan teknik personelin dinlenme anlarında kullanabilecekleri, sosyal anlamda vakit geçirebilecekleri bir iç avlu tasarımıdır.</p><p>Bu araştırmanın amacı; Laodikeia kazı evi iç avlusunun peyzaj tasarım süreci irdelenerek, estetik ve işlevsel tasarım ilkeleri açısından kullanıcı–ihtiyaç programı bağlamında değerlendirilmesidir.</p><p>Bu değerlendirmeler, işlevsel ve estetik açıdan kullanıcı kitlesinin çalışma–dinlenme gereksinimlerine cevap verebilcek, yapılı ve doğal çevre arasındaki uyumu gözeten peyzaj tasarım ilkeleri kapsamında proje geliştirilmiştir.</p><p> </p>
PROYECTO INVESTIGATIVO INSTITUCIONAL
Authors: Rozo Omar Parra 
Published: May 2015

<p>La investigación adquiere un papel preponderante en la Universidad, el cual debe fortalecerse mediante un trabajo disciplinario, interdisciplinario y transdisciplinario, dinamizado por procesos y proyectos de diversa índole. Como eje primordial de la academia, la investigación implica una decisión y un proyecto institucional que se plasma en un horizonte delimitado por sus proyectos, sus líneas y el trabajo en equipo. La suma de políticas, principios, criterios, estrategias y proyectos sólo puede hacerse realidad en la medida en que todos los implicados se comprometan a llevar a cabo lo planeado. Plantear el Proyecto Investigativo Institucional es el primer paso para generar y consolidar una cultura investigativa.</p>
ESTADO DEL ARTE DE LA INVESTIGACIÓN EN LA RELACIÓN SALUD-NIÑEZ, DESDE LA PSICOLOGÍA EN RELACIÓN CON LA MEDICINA, EN BOGOTÁ
Authors: O Ana Mercedes Abreo 
Published: May 2015

<p>Se presenta el estado del conocimiento sobre salud-niñez-componente psicológico y su relación en medicina y psicología (psicoanálisis, humanismo, conductismo, sistémico), en Bogotá, durante la década del 90. La metodología es un estado del arte de tipo analítico, corte mixto, teniendo como estrategias el análisis estadístico y de contenido que se desarrolló en las fases de contextualización, compilación de evidencias, clasificación, análisis, discusión de resultados y socialización. La poca investigación que se encuentra en contextos universitarios es discontinua y versa sobre temáticas originadas en el interés del investigador; no hay conceptualización explícita sobre salud, niñez, psique, ni avances disciplinares al respecto. La conceptualización estuvo referida a las temáticas estudiadas centradas en la enfermedad, su evaluación y tratamiento, donde el niño es el receptor del ambiente, influido por éste y, en ocasiones, víctima del mismo. El foco de la relación entre las categorías estuvo representado por la emoción como principal componente psicológico y por la incidencia del ambiente familiar sobre el niño. Desde la medicina, la psicología y dentro de los enfoques psicológicos, se encuentran puntos de convergencia y divergencia en cuanto a la comprensión de salud, niñez y su relación.</p>
3D Parametric design and static analysis of the first Spanish winch used to drain water from mines
Authors: Rojas Sola José Ignacio , Molino Delgado Jesús 
Published: May 2015

<p>En el presente artículo se analiza en detalle la primera máquina malacate desarrollada en España utilizada para la extracción del mineral. Se trata de un privilegio de invención diseñado por Bernave Dombon en 1850. En particular, se ha realizado el diseño paramétrico 3D con ayuda de software específico (Catia v5 R21) de cada uno de los elementos que componen el conjunto. Asimismo, una vez obtenido el modelo 3D, se ha realizado un análisis funcional estático mediante técnicas de Ingeniería Asistida por Ordenador realizado gracias al concurso del software de análisis por elementos finitos Simulia Abaqus v6.14-1, basadas en el análisis de las deformaciones, desplazamientos y tensión de von Mises, comprobando que las mayores concentraciones de tensiones se producen en el eje y en la estructura que soporta el tambor, y que la mayor concentración de desplazamientos se encuentra también en el eje del tambor, aunque no se produce en ningún caso la rotura de los elementos, por lo que resulta un conjunto bien dimensionado. </p>
Calidad de vida y adherencia al tratamiento de personas con enfermedad crónica oncológica
Authors: Castañeda Hernández Álvaro Hernando 
Published: May 2015

<p><strong>Introducción:</strong> La experiencia del cáncer afecta las dimensiones de la Calidad de vida (CV); la adherencia al tratamiento oncológico es un asunto poco descrito en la literatura científica, sin embargo, éste puede guardar relación con la calidad de vida de personas con enfermedad crónica oncológica, sobre todo en los primeros meses del diagnóstico. <strong>Materiales y Métodos: </strong>Estudio descriptivo, de correlación, cuantitativo y corte transversal. Participaron 158 personas con enfermedad crónica oncológica diagnosticadas entre 0 y 6 meses que asisten a una institución de tercer nivel de atención en salud de Bucaramanga, Colombia. Se aplicó la Escala de Calidad de vida versión paciente y el Instrumento para Evaluar los Factores que Influyen en la Adherencia a los Tratamientos Farmacológicos y no Farmacológicos en Pacientes con Riesgo de Enfermedad Cardiovascular. Para el análisis se utilizó estadística descriptiva y coeficiente de correlación lineal de Pearson. <strong>Resultados: </strong>La muestra, mayoritariamente mujeres, mayores de 60 años, de estratos bajos, dedicadas al hogar, principalmente con cáncer de mama, cérvix, piel; se observó analfabetismo en el 15%. La CV mostro media de 104.17 (DE 16.71). El 51% se ubicó en bajo riesgo y 41.75 riesgo medio para no adherirse. Se encontró relación débil positiva entre las dos variables r=,232 p=0,003. <strong>Discusión: </strong>La correlación lineal entre las dos variables en los pacientes con cáncer es menor que la descrita en estudios de otras condiciones de enfermedades crónicas no trasmisibles y crónicas infecciosas. <strong>Conclusiones: </strong>Hay relación débil entre la CV y los grados de riesgo para la adherencia al tratamiento y de las mismas con las dimensiones de cada variable.</p><p><strong><em>Cómo citar este artículo:</em></strong><em> Castañeda ÁH. </em><em>Calidad de vida y adherencia al tratamiento de personas con enfermedad crónica oncológica.<strong> </strong></em><em>Rev Cuid. 2015; 6(1): 906-13.</em><em> </em><em><a href="http://dx.doi.org/10.15649/cuidarte.v6i1.146">http://dx.doi.org/10.15649/cuidarte.v6i1.146</a></em></p>
Fatores intervenientes no seguimento do tratamento nutricional para redução de peso em mulheres atendidas em uma unidade básica de saúde do Brasil
Authors: Gonçalves Irene Da Silva Araújo , Ygnatios Ferreira Nair Tavares Milhem , Reis Paula Vargas dos Santos , Pena Geórgia Das Graças 
Published: May 2015

<p><strong>Introdução: </strong>A prevalência de excesso de peso cresceu consideravelmente nos últimos 30 anos representando um desafio para a Saúde Pública<em>. </em>Além disso, o padrão estético magro tem contribuído para a procura por atendimento nutricional, entretanto, a não adesão ao tratamento para perda de peso é elevada. Objetivo: Identificar os principais fatores intervenientes no seguimento ao tratamento nutricional para redução de peso em mulheres. <strong>Materiais e Métodos:</strong> Estudo transversal e descritivo contendo dados socioeconômicos, comportamentais e percepção do tratamento nutricional foi realizado em mulheres com idade maior ou igual a 18 anos em uma Unidade Básica de Saúde entre 2008-2010. Posteriormente, foram anotados dados antropométricos e número de consultas dos prontuários. <strong>Resultados:</strong> Aproximadamente 8% das mulheres melhoraram o estado nutricional e 3% atingiu os níveis de eutrofia. O diagnóstico de obesidade grau III se manteve na mesma proporção. Apenas 69,71% foram ao segundo retorno, 31,43% não perderam/ganharam peso, 58,29% perderam peso, sendo que 34,86% perderam até 3Kg. Os fatores intervenientes mais frequentes para não adesão ao tratamento foram: sensação de fome (38,31%), fracionamento da dieta (44,81%), controlar apetite/ansiedade/nervosismo (44,16%) e comer em menor quantidade (22,08%). Aproximadamente 40% considerou fácil a inclusão diária de frutas/hortaliças, preferência por preparações com menor teor de gordura/alimentos integrais, redução de açúcar/doces/refrigerantes/lanches. <strong>Discussão e Conclusões: </strong>Foram observadas baixa frequência de comparecimento às consultas e de perda de peso. Os fatores intervenientes mais frequentes foram relacionados ao controle emocional e fisiológico da fome. São necessárias estratégias motivacionais e focadas no indivíduo na tentativa de potencializar resultados do tratamento utricional.</p><p><strong><em>Cómo citar este artículo:</em></strong><em> Goncalves I, Ferreira N, Reis P, Pena G</em><em>.</em> <em>Fatores intervenientes no seguimento do tratamento nutricional para redução de peso em mulheres atendidas em uma unidade básica de saúde do Brasil</em>.<strong> </strong><em>Rev Cuid. 2015; 6(1): 914-22.</em><em> </em><a href="http://dx.doi.org/10.15649/cuidarte.v6i1.157"><em>http://dx.doi.org/10.15649/cuidarte.v6i1.157</em></a><em> </em></p>