bluuebunny/crossref_metadata_2025_split huggingface dataset:
A multisite, community oncology‐based randomized trial of a brief educational intervention to increase communication regarding complementary and alternative medicine
Authors: Parker Patricia A. , Urbauer Diana , Fisch Michael J. , Fellman Bryan , Hough Holly , Miller Jessica , Lanzotti Victor , Whisnant Mindy , Weiss Matthias , Fellenz Lori , Bury Martin , Kokx Patricia , Finn Kathleen , Daily Maureen , Cohen Lorenzo 
Published: July 2013

BACKGROUNDThe use of complementary and alternative medicine (CAM) is widespread, yet there is relatively little discussion regarding its use between oncology patients and their health care practitioners.METHODSThis multisite randomized trial examined the efficacy of an educational intervention designed to encourage oncology nurses to discuss CAM use with their patients. A total of 175 nurses completed questionnaires about discussing CAM use with patients at baseline and 2 months after the intervention. Patients at baseline (N = 699) and different patients at follow‐up (N = 650) completed questionnaires regarding CAM.RESULTSAt the 2‐month follow‐up, nurses in the intervention reported they were more likely to ask about CAM use than those in the control group (odds ratio, 4.2; P = .005). However, no significant effect was found for the percentage of patients who indicated that they were asked about CAM use (odds ratio, 2.1; P > .10). Approximately 40% of patients reported using CAM after their cancer diagnosis, yet the majority of nurses estimated that < 25% of their patients were using CAM.CONCLUSIONSCAM use in community‐based oncology patients is common and is underestimated by oncology nurses. The brief, low‐intensity intervention presented herein was found to be sufficiently powerful to change nurses' perceptions of their behavior but may not have been intensive enough to yield changes that were evident to patients. Cancer 2013;119:3514–3522.. © 2013 UT MD Anderson Cancer Center. Cancer published by Wiley Periodicals, Inc. on behalf of American Cancer Society.
Raman Spectroscopic Investigation on TiO2–N719 Dye Interfaces Using Ag@TiO2 Nanoparticles and Potential Correlation Strategies
Authors: Qiu Zhi , Zhang Meng , Wu De‐Yin , Ding Song‐Yuan , Zuo Qi‐Qi , Huang Yi‐Fan , Shen Wei , Lin Xiao‐Dong , Tian Zhong‐Qun , Mao Bing‐Wei 
Published: July 2013

AbstractHerein, we employ Ag@TiO2 core–shell nanoparticles for surface‐enhanced Raman scattering (SERS) investigations of TiO2–N719 dye interfaces. In situ electrochemical SERS investigations of the Ag@TiO2–N719 interaction are systematically carried out under a series of electrode‐potential controls. By comparing the potential dependence of resonant and pre‐resonant SERS spectra recorded with different laser excitations, bidentate carboxylate linkage is considered to be involved in N719 adsorption on TiO2. Meanwhile, SCN ligand shows obvious interactions with TiO2, and their role in the adsorption and orientation of N719 on TiO2 should not be underestimated. The in situ SERS spectra of Ag@TiO2 show a clear bell‐shaped intensity–potential relation for the major bands of N719. A molecule‐to‐TiO2 charge‐transfer resonance is tentatively attributed to account for such a phenomenon. Under the influence of such a charge‐transfer resonance, valuable information about the N719–TiO2 interaction as well as the intramolecular deformation of N719 is obtained.
Gut Microbiota and Probiotics: Current Status and Their Role in Cancer Therapeutics
Authors: Khan Abdul Arif , Khurshid Mohsin , Khan Shahanavaj , Alshamsan Aws 
Published: July 2013

Abstract

Preclinical Research

The microbiome is a collection of all microbial species that coexist with an individual. These organisms influence several aspects of individual body functions. Probiotic organisms are generally beneficial components of microflora and confer normal health status. Usually, probiotics should be provided from the outside in the diet for maintaining proper health status. Probiotics can also have a significant impact on cancer management. While the results toward cancer management with probiotics are promising, careful risk assessment of probiotics use in cancer patients, who are usually immunocompromised due to radical therapy, comes as a great demand. This article provides an overview of the current research status of probiotics use in cancer patients and discusses the role of probiotics in cancer management.
Deleterious effect of glycation on the ability of HDL to counteract the inhibitory effect of oxidized LDL on endothelium‐dependent vasorelaxation
Authors: Brindisi M. C. , Duvillard L. , Monier S. , Vergès B. , Perségol L. 
Published: July 2013

AbstractBackgroundContrary to high‐density lipoprotein (HDL) from normolipidaemic and normoglycaemic subjects, HDL from diabetic patients loses its ability to reverse the inhibition of vasorelaxation induced by oxidized low‐density lipoprotein (LDL). The aim of this study was to analyze the role of glycation, a major abnormality observed in diabetes, on the impairment of the vasorelaxant effect of HDL.MethodsHDL from healthy subjects was glycated in vitro by incubation in glucose 200 mmol/L for 3 days. Vasoreactivity was evaluated by the relaxation response to acetylcholine of rabbit aorta rings pre‐contracted with noradrenaline, before and after 2 h incubation with or without different lipoprotein fractions (Krebs buffer, oxidized LDL, normal or glycated HDL alone and with oxidized LDL).ResultThe fructosamine/apolipoprotein AI ratio was significantly increased in glycated HDL compared with native HDL (53.63 ± 7.91 vs 18.51 ± 4.10 µmol/g; p < 0.05). Oxidized LDL inhibited endothelium‐dependent vasodilation compared with Krebs buffer [maximal relaxation (Emax) = 53.15 ± 6.50 vs 98.67 ± 2.07%, p < 0.001]. Native HDL was able to counteract the oxidized LDL‐induced inhibition of vasorelaxation (Emax = 76.93 ± 5.41 vs 53.15 ± 6.50%, p < 0.001). On the other hand, glycated HDL had no effect on oxidized LDL‐induced inhibition of endothelium vasorelaxation compared with incubation with oxidized LDL alone (Emax = 52.98 ± 2.07 vs 53.15 ± 6.50%, not significant).ConclusionGlycation of HDL induces the loss of the ability of HDL to counteract the inhibitory effect of oxidized LDL on endothelium‐dependent vasorelaxation, this is likely contributing to the impairment of antiatherogenic properties of HDL in diabetic patients. Copyright © 2013 John Wiley & Sons, Ltd.
Separation of Lipids on Human Very Low‐density Lipoproteins by Micellar Electrokinetic Chromatography
Authors: Lai Wei‐Ting , Liao Yi‐Han , Xie Huai‐Guang , Liu Yi‐Ning , Lin Yi‐Jyun , Liu Mine‐Yine 
Published: July 2013

AbstractLiquid‐phase and solid‐phase extractions (SPE) in combination with a simple micellar electrokinetic chromatography (MEKC) method were used to investigate human very low‐density lipoprotein (VLDL) lipids for two healthy donors. At absorbance 200 nm, the effective mobilities and peak areas of the MEKC profiles showed good reproducibility and precisions. A major peak and several minor peaks appeared for the total lipids of native VLDL, but both the peak numbers and areas reduced for the in vitro oxidized VLDL. Two chloroform and two methanol fractions were obtained from SPE of VLDL total lipids. Significant differences were observed for the first methanol fraction between native and in vitro oxidized VLDL lipids. The first methanol fraction showed a major peak and several minor peaks for native VLDL, but both the peak numbers and areas reduced for oxidized VLDL. Oxidation of VLDL caused decomposition of lipids, and thus the reduction of peak numbers and areas.
Effects of Divalent Metal Ions on the Chaperone Activity and Structure of Rat Lens H18G Mutant αB‐Crystallin
Authors: Lu Shou‐Yun , Huang Fu‐Yung 
Published: July 2013

AbstractαB‐crystalin, a small heat shock protein and a component of α‐crystalin, is a molecular chaperone playing an important role in preventing the formation of cataracts. It has been reported that His18 is an important site for Cu2+ to bind with to form a stable metal complex and thus to enhance this chaperone‐like activity of human αB‐crystalin. In this work, we used site‐directed mutagenesis to clone and express H18G rat lens αB‐crystalin in order to investigate the role of His18 in chaperoning activity. We found that 1 mM of Cu2+, or Zn2+, rather than Mg2+, significantly enhanced the chaperone‐like activity of wild type αB‐crystalin. Whereas, it is Zn2+ and Mg2+, not Cu2+, that significantly reduced this activity of H18G αB‐crystalin. In the absence of cation, H18G showed better activity compared to the wild type αB‐crystalin. ANS fluorescence measurement showed there was no linear relationship between chaperone‐like activity and surface hydrophobicity, indicating that surface hydrophobicity is not a prerequisite for chaperone‐like activity. An HPLC size‐exclusion chromatography study showed that in the presence of metal ions, wild type αB‐crystalin tended to aggregate via dissociation and re‐association into a high molecular aggregate with a molecular weight higher than 1400 kDa and then precipitated, suggesting that the presence of metal ions is a factor leading to the formation of cataracts. Both the near and far UV‐CD spectra suggested that the wild type αB‐crystalin reflected more β‐sheet structural characteristics; whereas the H18G reflected more random coil characteristics. The H18G induced structural alterations as to develop more random coil characteristics and more micro‐environmental changes around the tryptophan residues. This work suggested that His18 may not be a crucial binding site for Cu2+, but rather that it may be an important binding site for Zn2+ in terms of chaperone‐like activity and the process of metal induced self‐aggregation is prerequisite for chaperone‐like activity to occur.
The influence of oxidation on the tribological performance of diester lubricant
Authors: Wu Yanxia , Li Weimin , Wang Xiaobo 
Published: July 2013

ABSTRACTThe oxidative degradation test of di‐2‐ethylhexyl sebacate (DEHS) was carried out by a sealed stainless steel reactor. Fourier transform infrared spectroscopy and gas chromatography–mass spectrometry (GC–MS) were utilised to characterise the chemical composition and molecular structure of the oxidation products. The results revealed that 2‐ethyl‐1‐hexanol and mono(2‐ethylhexyl)sebacate were major degradation products in the liquid phase. Tribological behaviour was measured using a four‐ball tester. Scanning electron microscopy was employed to investigate the morphologies of the worn surface. Tribological results showed that anti‐wear and friction‐reducing performances of DEHS were highly dependent on the chemical composition of the oxidation products generated during the test. The hydroperoxides formed during the initial oxidation process could deteriorate lubrication properties of DEHS. However, certain amount of highly polar degradation products (acids and alcohols) generated could significantly improve the friction‐reducing performance of DEHS by the formation of boundary adsorption films on the rubbing surfaces. Copyright © 2013 John Wiley & Sons, Ltd.
Asynchronous collision integrators: Explicit treatment of unilateral contact with friction and nodal restraints
Authors: Wolff Sebastian , Bucher Christian 
Published: July 2013

SUMMARYThis article presents asynchronous collision integrators and a simple asynchronous method treating nodal restraints. Asynchronous discretizations allow individual time step sizes for each spatial region, improving the efficiency of explicit time stepping for finite element meshes with heterogeneous element sizes. The article first introduces asynchronous variational integration being expressed by drift and kick operators. Linear nodal restraint conditions are solved by a simple projection of the forces that is shown to be equivalent to RATTLE. Unilateral contact is solved by an asynchronous variant of decomposition contact response. Therein, velocities are modified avoiding penetrations. Although decomposition contact response is solving a large system of linear equations (being critical for the numerical efficiency of explicit time stepping schemes) and is needing special treatment regarding overconstraint and linear dependency of the contact constraints (for example from double‐sided node‐to‐surface contact or self‐contact), the asynchronous strategy handles these situations efficiently and robust. Only a single constraint involving a very small number of degrees of freedom is considered at once leading to a very efficient solution. The treatment of friction is exemplified for the Coulomb model. Special care needs the contact of nodes that are subject to restraints. Together with the aforementioned projection for restraints, a novel efficient solution scheme can be presented. The collision integrator does not influence the critical time step. Hence, the time step can be chosen independently from the underlying time‐stepping scheme. The time step may be fixed or time‐adaptive. New demands on global collision detection are discussed exemplified by position codes and node‐to‐segment integration. Numerical examples illustrate convergence and efficiency of the new contact algorithm. Copyright © 2013 The Authors. International Journal for Numerical Methods in Engineering published by John Wiley & Sons, Ltd.
Robust constrained economic receding horizon control applied to the two time‐scale dynamics problem of a greenhouse
Authors: González Ramón , Rodríguez Francisco , Guzmán José Luis , Berenguel Manuel 
Published: July 2013

SUMMARYThis paper discusses the formulation of an optimal control framework for a two time‐scale system modeled in terms of singular perturbation theory. The fast dynamics subsystem is controlled online by means of a robust receding horizon control approach considering economic objectives in the performance function and fulfilling state and input constraints. The formulation is addressed in general terms, so it can be adapted to different applications. A practical example is given, greenhouse crop growth control. Simulations comparing the proposed controller with another two time‐scale control strategy demonstrate constraints fulfillment and a proper performance, assuming uncertainty in the weather conditions during the predictions. Copyright © 2013 John Wiley & Sons, Ltd.
Communications over phase noise channels: a tutorial review
Authors: Colavolpe Giulio 
Published: July 2013

SUMMARYIn this tutorial paper, we first review the main information–theoretic results on channels affected by a time‐varying phase noise. The main maximum a posteriori symbol detection algorithms to be employed in such a challenging scenario are then described considering linear modulations and advanced coding schemes based on iterative detection and decoding. The role of pilot symbols will be also discussed. Copyright © 2013 John Wiley & Sons, Ltd.
Using iPads to teach inquiry science to students with a moderate to severe intellectual disability: A pilot study
Authors: Miller Bridget T. , Krockover Gerald H. , Doughty Teresa 
Published: July 2013

AbstractMultiple illustrative case studies were used to investigate guided inquiry methods and the benefits of traditional science notebooks versus electronic science notebooks for students with moderate to severe intellectual disabilities. Results indicated students successfully acquired science content and increased motivation through science inquiry instruction using both methods. However, each student demonstrated higher motivation, engagement, and independence in inquiry investigation with the use of iPad® electronic notebooks. © 2013 Wiley Periodicals, Inc. J Res Sci Teach 50: 887–911, 2013
Is Georgia the Next “New” Wine-Exporting Country?
Authors: Anderson Kym 
Published: July 2013

AbstractThe former Soviet republic of Georgia is reputedly the cradle of wine and has enjoyed at least 8,000 vintages. It has also been a major supplier of wine to Russia for at least 200 years, but to few other countries. In 2006, however, Russia imposed a ban on beverage imports from Georgia. Since then this relatively poor country, in which nearly half the population is rural and most farmers have a vineyard, has been seeking to develop new export markets for its wine. This paper assesses the potential for growth in Georgia's wine production and exports. It then outlines ways to addresses the challenges involved in trying to realize that potential, drawing on the experience of other countries that have rapidly expanded their wine exports in the past two decades. Implications for policy are drawn, particularly for ensuring that poverty is reduced as exports expand and the economy grows. (JEL Classifications: F14, F15, F54, Q17)
Does phloem-based resistance to aphid feeding affect host-plant acceptance for reproduction? Parturition of the pea aphid,Acyrthosiphon pisum, on two near-isogenic lines ofMedicago truncatula
Authors: Nam K. Jung , Powell G. , Hardie J. 
Published: July 2013

AbstractProbing behaviour (prior to parturition) and parturition of two clones (PS01 and N116) of the pea aphid,Acyrthosiphon pisumon two genotypes (near-isogenic lines (NILs)) (Q174_5.13 and Q174_9.10) ofMedicago truncatulawere investigated using electrical penetration graph (EPG) coupled with simultaneous visual monitoring for parturition. Line Q174_5.13 has been reported to show a phloem-based resistance to feeding in the clone PS01 but to be susceptible to the clone N116, whereas Q174_9.10 has shown to be susceptible to both aphid clones. The time taken to first parturition by clone PS01 was similar on Q174_5.13 and Q174_9.10. Prior to parturition, no aphids on Q174_5.13 contacted phloem, but 5% of the aphids on Q174_9.10 showed phloem salivation (recognized by EPG pattern E1). No phloem contact was observed with aphid clone N116 on either NILs ofMedicagobefore first parturition occurred, and the time taken to first larviposition was similar on Q174_5.13 and Q174_9.10. The results indicate that the initiation of parturition of the clone PS01 and N116 on both NILs does not require the phloem contact and seems unchanged by a phloem-based resistance mechanism to feeding onMedicago. This finding suggests that host recognition and decisions about parturition occur before phloem contact or ingestion, and act independently onR-gene-mediated resistance.
Spoken Greek
Authors: Loader W. R 
Published: July 2013

It has been suggested that there is less difference between ancient Greek and modern Greek than between present-day English and Chaucer's language. The suggestion is somewhat questionable. Broadly speaking, apart from dialects and local variations, there are presently three languages in Greece, the Kathareuousa, the Demotiki, and the popular newspaper language, which is a blend of the two.The Kathareuousa is the official and formal language, used in Government publications and statements, business correspondence, non-fictional books and treatises, law courts, University lectures, and in formal conversation. And although its grammatical structure is analytic as opposed to the synthesis of ancient Greek (a change which constitutes the main difference between classical and modern Greek, as it does between other modern and ancient languages), in the Kathareuousa the most strenuous attempt has been made to maintain the accidence and vocabulary of the ancient language.Words are declined and verbs conjugated (without some of their more difficult and less used moods and tenses) as in Attic Greek, pronouns and prepositions and the cases governed by them are the same, and while, naturally, many terms which describe things known only to the modern world are not to be found in Liddell and Scott, they are generally legitimate and intelligible compounds of words which are to be found in Liddell and Scott. Ἀɛροπλἁνoν for aeroplane, ἀɛρòσTαtoν for balloon, are instances which come easily to mind.
Greek and the Factory Worker
Authors: Carey R. M. 
Published: July 2013

About a year ago a group of Rugby School masters planned a short residential course for factory workers; and Shakespeare, History, Poetry, Religion, Music, and Geography seemed the obvious subjects to choose. In addition, a few lectures on Classics were proposed and provoked the inevitable reaction: ‘surely that's dead; why can't you bury it?’, ‘the world has passed through that phase’, and so on. But in spite of these protests six lectures, each lasting an hour, were allotted to the Civilization of Ancient Greece.As general organizer I regarded these lectures as the most interesting feature of the course: it is perhaps relevant to add that I had read very little Greek since taking Matriculation thirty years before, and so I felt sufficiently detached to judge impartially. It was easy to guess that in prospect these lectures would be unpopular; and indeed, before the first, I heard students saying that no one expected to enjoy the Greek. So we decided to watch carefully; and if, after three lectures, there were little interest shown, then we were prepared to cancel the remainder. But it was soon abundantly clear that there was no risk of failure, and by the third lecture Greek was evidently one of the most successful features of a course that was enjoyed by all. Here are a few sentences from various letters sent by the students after the course: ‘I thought that the subjects were too “classic”, especially the last one (Ancient Greek civilization)…. Now I know that these subjects are vital for anyone who is to get the most out of life’; ‘Doors were opened to me into new worlds of delight’, meaning poetry and classics; ‘What a change from technical studies which unfortunately resume next week: I now feel that I want to give up engineering… gave me the incentive to go farther afield and delve deeper into the classics’; ‘Two weeks of exquisite delight’… with later special reference to the Greek class; ‘Greek culture and literature for instance seemed such dry subjects before, but now I realize how much we can learn from them and how very similar their problems were to those confronting us to-day.’
My Lady's Toilet
Authors: Walton F. T. 
Published: July 2013

The modern miss will sometimes ask, ‘Did the ladies in ancient Greece and Rome use “make-up”?’ They most certainly did. It would, indeed, be true to say that nearly all modern artificial aids to beauty had their counterparts in classical antiquity: hair, eyebrows, eyelids, eyelashes, and cheeks all had their own ‘preparations’ guaranteed to enhance woman's natural charms.In Homer, both sexes after washing anoint themselves with oil, but of cosmetics in the usual sense of the word there is no trace. Soon, however, the Greek ladies, finding, we are told, that the sedentary life imposed upon them by convention caused their complexions to fade, eagerly adopted those devices that the Eastern races had so long employed to add to their charms; and it is clear that the ladies of Rome became even more enthusiastic than their sisters in Athens in their endeavours to improve upon nature.Frequently my lady did not bother to use cosmetics when at home—Quando videri vult formosa domi? Juvenal asks in disgust—but on special occasions, or when going to meet an admirer, she appeared in all her brilliance. The aid of white lead (Ψרμύθιοѵ, cerussa) was often called upon to produce a fair complexion, although its use cannot have been wholly free from risk; or a chalky powder (creta) was employed. Means of reddening the cheeks were obtained from the alkanet root (ἂγχoυνσα)—a dye which is still used to-day; from the crushed fruit of the mulberry (συκἁμινoν, morum) or the elderberry(acinus ebuli); from the poppy (papaver); and from a plant which we cannot identify (παιέρως) but which was guaranteed to give ‘that schoolgirl complexion’ a darker tint could be obtained from a composite preparation known as purpurissum.