bluuebunny/crossref_metadata_2025_split huggingface dataset:
Variasi Konsentrasi Senyawa Fitokimia Sirih Merah Dan Pelarut Heksana Menggunakan Gas Chromatography – Mass Spectrometry
Authors: Ardiansyah Ardiansyah , Wicaksono Ardian Trio 
Published: August 2024

Penelitian ini bertujuan untuk optimalisasi metode penetapan senyawa fitokimia dalam sirih merah (Piper crocatum) menggunakan teknik maserasi dengan pelarut n-heksana dan Gas Chromatography – Mass Spectrometry (GC-MS) melalui berbagai variasi konsentrasi. Sirih merah dikenal memiliki senyawa fitokimia sehingga berpotensi dalam pengembangan metode ekstraksi. Diperlukan analisis yang mendalam untuk pemahaman yang lebih komprehensif terhadap komposisi kimia tanaman ini terutama mempertimbangkan variasi konsentrasi dalam sampel. Penelitian terhadap komposisi fitokimia dalam sirih merah menjadi sangat penting dalam upaya memahami potensinya pada kesehatan dan produk herbal lainnya. Daun sirih merah dihaluskan dan diekstraksi dengan pelarut n-heksana melalui metode maserasi. Selanjutnya dilakukan variasi konsentrasi (volume/volume) pada larutan ekstrak yang dihasilkan. Kemudian, dilakukan analisis GC-MS pada setiap variasi konsentrasi untuk memperoleh profil senyawa fitokimia. Hasil penelitian menunjukkan bahwa metode maserasi dengan pelarut n-heksana efektif dalam mengekstraksi senyawa-senyawa fitokimia dari sirih merah. Variasi konsentrasi yang tepat pada 400/1000 sampai dengan 600/1000. Variasi konsentrasi dalam analisis GC-MS memberikan informasi tambahan mengenai respons senyawa-senyawa terhadap perubahan konsentrasi sehingga memperkaya pemahaman kita tentang komposisi kimia tanaman ini. Hasil ini diharapkan dapat mendukung pemahaman lebih lanjut tentang pemanfaatan sirih merah secara optimal dalam bidang penelitian, praktikum, farmasi dan produk kesehatan berbasis herbal.
PROBLEMATIKA PEMBELAJARAN KITAB KUNING PROGRAM TAKHASHUS DI MA’HAD AL-JAMI’AH AL-ALY UNIVERSITAS ISLAM NEGERI (UIN) MAULANA MALIK IBRAHIM MALANG
Authors: Mubarok Ahmad Fahmi 
Published: August 2024

The yellow book learning is the hallmark of pesantren, and is even one of the most appropriate media for strengthening student character, in addition to the formation and development of values ​​taught in pesantren. The Takhashsus program at Ma'had Al-Jami'ah Al-Aly UIN Malang with a student background studying in different majors applies a learning model with the sorogan method that is adapted to the busy student activities. As a Ma'had under the auspices of the campus, Ma'had Aly UIN Malang makes the Takhashsus program a means to monitor the reading ability of Mahasantri books by emphasizing linguistic aspects and understanding abilities. Another goal is to improve the ability to read the book by habituation. The results of the research through observations and interviews showed that the problems faced in learning the yellow book were low motivation, limited teaching staff, non-conducive time and place and an unsupportive social environment.

Abstrak
Pembelajaran kitab kuning menjadi ciri khas pesantren, bahkan salah satu media yang paling tepat penguatan karakter siswa, selain pembentukan dan pembinaan tata nilai yang diajarkan di pesantren. Program Takhashsus di Ma’had Al-Jami’ah Al-Aly UIN Malang dengan latar belakang Mahasantri yang berkuliah di jurusan yang berbeda-beda menerapkan model pembelajaran dengan metode sorogan yang disesuaikan dengan kegiatan Mahasiswa yang padat. Sebagai Ma’had yang berada di bawah naungan kampus, Ma’had Aly UIN Malang menjadikan program Takhashsus sebagai sarana untuk memantau kemampuan baca kitab Mahasantri dengan menekankan pada segi linguistik dan kemampuan pemahaman. Tujuan lainnya adalah untuk meningkatkan kemampuan baca kitab dengan cara pembiasaan. Hasil riset melalui observasi dan wawancara menunjukkan bahwa problematika pembelajaran kitab kuning yang dihadapi adalah rendahnya motivasi, terbatasnya tenaga pengajar, waktu dan tempat yang tidak kondusif dan lingkungan sosial yang kurang mendukung.
PENGGUNAAN METODE MAKE A MATCH UNTUK MENINGKATKAN HASIL BELAJAR MATERI IMAN KEPADA RASUL SISWA KELAS IV SD NEGERI 2 BABADAN KEC. NGAJUM
Authors: Khasanah Uswatun , Sulalah Sulalah , Arifa Laily Nur 
Published: August 2024

This research is based on the issue of how the use of the "make a match" method can improve students' learning outcomes in the subject of belief in the prophets in the fourth-grade class at SD Negeri 2 Babadan, Ngajum District. The objective of this research is to describe the use of the "make a match" method in improving students' learning outcomes in Islamic Religious Education (PAI) on the subject of belief in the prophets at SD Negeri 2 Babadan, Ngajum District. This research employs a classroom action research with two cycles. Each cycle consists of 4 stages: planning, action, observation, and reflection. The target of this research is fourth-grade students. The data obtained include learning outcomes and observation sheets of teaching and learning activities. The analysis results indicate that students' learning outcomes have improved from Cycle I to Cycle II. In the pre-cycle, 17% of students completed the material, in Cycle I, 50% of students completed the material, and in Cycle II, 100% of students completed the material above the Minimum Mastery Criteria (KKM). The conclusion of this research is that the use of the "make a match" method can improve students' learning outcomes.

Abstrak
Penelitian ini berdasarkan permasalahan Bagaimanakah penggunaan metode make a match dalam meningkatkan hasil belajar siswa pada materi iman kepada rasul kelas IV SD Negeri 2 Babadan Kec.Ngajum. Sedangkan tujuan dari penelitian ini adalah Untuk mendeskripsikan penggunaan metode make a match dalam meningkatkan hasil belajar siswa pada mata pelajaran PAI materi iman kepada rasul di SD Negeri 2 Babadan Kec. Ngajum. Penelitian ini menggunakan penelitian tindakan kelas sebanyak dua siklus. Setiap siklus terdiri dari 4 tahap yaitu, perencanaan, tindakan, observasi, dan refleksi. Sasaran penelitian ini adalah siswa kelas IV. Data yang diperoleh berupa hasil belajar, lembar observasi kegiatan belajar mengajar. Dari hasil analis didapatkan bahwa hasil belajar siswa mengalami peningkatan dari siklus I sampai siklus II yakni, pra-siklus 17% siswa tuntas, siklus I 50% siswa tuntas dan siklus II 100% siswa tuntas diatas KKM. Simpulan dari penelitian ini penggunaan metode make a match dapat meningkatkan hasil belajar siswa.
A STUDY OF THE CAUSES OF THE EASE OF MEMORIZING: Review In The Book Ta’lim Muta’lim By Imam Al-Zarnuji
Authors: Nur Afidah Rohmatun , Hafidzi Anwar 
Published: August 2024

The book of Ta'lim Muta'allim by Imam Al-Zarnuji is one of the classical works that discusses the ethics and methods of learning for knowledge seekers. This study aims to identify and analyze the factors that cause ease of memorization as described in the book. The research method used is a literature study with an analytical descriptive approach to the text of Ta'lim Muta'allim. The results show that there are several main factors that support the ability to memorize, including sincere intentions, discipline in learning, a conducive environment, and support from teachers and peers. In addition, the learning methods recommended by Imam Al-Zarnuji such as repetition, deep understanding, and practical application also play an important role in improving memorization ability. This research is expected to contribute to the development of effective learning methods in the context of Islamic education.

Abstrak
Kitab Ta'lim Muta'allim karya Imam Al-Zarnuji merupakan salah satu karya klasik yang membahas tentang etika dan metode belajar bagi para penuntut ilmu. Penelitian ini bertujuan untuk mengidentifikasi dan menganalisis faktor-faktor yang menyebabkan kemudahan menghafal sebagaimana dijelaskan dalam kitab tersebut. Metode penelitian yang digunakan adalah studi literatur dengan pendekatan deskriptif analitis terhadap teks kitab Ta'lim Muta'allim. Hasil penelitian menunjukkan bahwa terdapat beberapa faktor utama yang mendukung kemampuan menghafal, di antaranya adalah niat yang ikhlas, kedisiplinan dalam belajar, lingkungan yang kondusif, serta dukungan dari guru dan teman sejawat. Selain itu, metode pembelajaran yang direkomendasikan oleh Imam Al-Zarnuji seperti pengulangan, pemahaman yang mendalam, dan aplikasi praktis juga memainkan peran penting dalam meningkatkan kemampuan menghafal. Penelitian ini diharapkan dapat memberikan kontribusi bagi pengembangan metode pembelajaran yang efektif dalam konteks pendidikan Islam.
KEPRIBADIAN TOKOH UTAMA DALAM NOVEL الأجنحة المتكسرة KARYA KAHLIL GIBRAN
Authors: Wahida Mizatul , . Mashyur , Sumarna Luqman 
Published: August 2024

Salah satu bentuk karya sastra adalah novel. Menurut paham genetik, novel sebagai sebuah teks merupakan ekspresi menyeluruh dari pribadi pengarang dan latar belakang budaya nya. Keduanya mencakup banyak hal antara lain kepribadian penulis, kondisi psikologi, selera, keterampilan, kondisi sosial, pengalaman, kemampuan, dan berbagai peristiwa disekitarnya. Novel merupakan medium bagi seorang penulis untuk mencurahkan gagasannya berdasarkan struktur mental trans-individual dari anggota masyarakat tempat dia hidup.
Novel ini dipilih untuk diteliti karena memiliki nilai sastra yang tinggi yaitu memiliki nilai estetika dan makna yang dalam. Novel al-Ajnihah al-Mutakassirah merupakan novel best seller Kahlil Gibran karena novel tersebut merupakan novel perdana yang diterjemahkan hampir keseluruh bahasa di dunia. Novel ini lahir karena terinspirasi dari sebuah kisah cinta Gibran yang menggetarkan, menarik dan mengesankan namun berakhir tragis bersama seorang gadis yang dicintainya yang bernama Selma.Bagi Gibran, cinta adalah standing in (bertahan di dalam). Itu berarti cinta lebih pada sebuah tindakan aktif yang bersifat memberi ketimbang menerima. Selain elegi cinta yang sangat mengharukan, Gibran juga menyelipkan pandangannya mengenai berbagai masalah yang berkaitan dengan nasib perempuan, penindasan, ketidakadilan, dan korupsi yang terjadi di Lebanon.
Pengaruh dari novel al-Ajnihah al-Mutakassirah yang ditulis oleh Kahlil Gibran ini terasa sangat besar di dunia Arab, karena di sini untuk pertama kalinya wanita-wanita Arab

yang dinomorduakan mempunyai kesempatan untuk berbicara bahwa mereka adalah istri yang memiliki hak untuk memprotes struktur kekuasaan yang diatur dalam perkawinan.
Study On Analysis Of Pre-Marriage Couple's Perceptions Of Partnership Gender In The Domestic Areas In Yogyakarta
Authors: Khasanah Nur , Riska Herliana , Santika Ni Kadek Giri 
Published: August 2024

The COVID-19 pandemic, which has occurred, followed by a global crisis and the issue of recession in various parts of the world, including Indonesia, has had a vulnerable impact on family resilience. This can be seen from the phenomenon of a significant increase in the prevalence of divorce from 291,677 in 2020, which increased by 53% to 447,743 in 2021, which places Indonesia as the country with the highest prevalence of divorce in Asia-Africa. This is directly proportional to the high prevalence of single parents, which places Indonesia in the second-highest position in the world with fatherless countries and DI. Yogyakarta ranks third highest in Indonesia. According to the Indonesian Ministry of Religion, the phenomenon of divorce is dominated by contested divorce from wives, namely 73.7%, with the reason being ongoing disputes at 62.4%. Various factors, including gender inequality in the domestic sphere, cause the disputes. The research method used was qualitative, with an explanatory research approach to 34 informants who were prospective premarital couples in the KUA Depok Yogyakarta work area. Data was collected through FGDs and deep interviews to explore prospective partners' perceptions of gender partnership in the family—purposive sampling technique according to inclusion criteria. Data analysis uses phenomenological studies, including data familiarization through identifying thematic frameworks, data indexation, coding and charting, and data interpretation carried out independently by the researcher. The research results show that the lowest knowledge of respondents regarding family functions is the socio-cultural function, namely ten respondents (29.41%), followed by the coaching function, namely 14 respondents (41.17%), and the reproductive function, namely 16 respondents (47.06%).
The Relationship of Heavy Metals With Lung Cancer: A Systematic Review
Authors: Mohammed Mostafa Salim 
Published: August 2024

General Background: Heavy metals such as lead, cadmium, nickel, and copper are known environmental pollutants with established toxic effects on human health. Specific Background: These elements have been identified as significant contributors to various diseases, with emerging evidence suggesting their role in promoting cancer, particularly lung cancer. Knowledge Gap: Although numerous studies have investigated the relationship between heavy metals and lung cancer, a comprehensive understanding of the impact of various metal concentrations on cancer development and progression remains underexplored. Aims: This systematic review aims to consolidate and analyze the existing literature on the effects of heavy metal exposure on lung cancer, focusing on different biological samples such as plasma, urine, nails, and hair. Results: The review identified consistent evidence linking increased levels of heavy metals with higher risks of lung cancer. Studies highlighted the role of metals like cadmium, chromium, and nickel in not only promoting cancer growth but also in impacting the efficacy of cancer treatment. The findings suggest that exposure to these metals, often from environmental and industrial sources, is a critical risk factor for lung cancer. Novelty: This review uniquely synthesizes data from diverse biological samples, providing a holistic view of how heavy metal exposure influences lung cancer. Implications: The study underscores the importance of monitoring and regulating heavy metal exposure to reduce the incidence of lung cancer. It also emphasizes the need for further research to develop targeted strategies for mitigating the risks associated with heavy metal-induced carcinogenesis.
Highlights:

Heavy metals like cadmium increase lung cancer risk significantly.
Diverse samples (plasma, urine) reveal metals' impact on cancer.
Regulating metal exposure is key to preventing lung cancer.

Keywords: Heavy Metals, Lung Cancer, Cadmium, Carcinogenesis, Toxic Exposure
Placental-derived mesenchymal stem cells restore ovarian function and metabolic profile in the rat model for polycystic ovarian syndrome
Authors: Sarvestani Mojtaba , Rajabzadeh Alireza , Mazoochi Tahereh , Samimi Mansooreh , Navar Mohsen , Moradi Faezeh 
Published: August 2024

Abstract

Introduction
Polycystic ovary syndrome (PCOS) is an endocrine and metabolic disturbance that affects many women worldwide and is characterized by chronic anovulation, hyperandrogenism, and ovarian dysfunction. Infertility, insulin resistance, dyslipidemia, and liver dysfunction are perturbations induced by PCOS. Mesenchymal stem cells (MSCs) have recently emerged as a potential therapy for metabolic disorders such as PCOS due to their anti-inflammatory, antiapoptotic, proangiogenic, and proliferative properties. Placenta-derived mesenchymal stem cells (PDMSCs) are derived from the placenta and have advantages over other sources of MSCs in terms of availability, safety, and immunomodulation.
Materials and Methods
In this experimental study, we assigned twenty female Wistar rats into four groups (n = 5): control, sham, PCOS, and PCOS-PDMSCs. We induced PCOS in the rats by administering letrozole for 21 days. PDMSCs (1 × 106 cells) were injected through the tail vein. Fourteen days after cell infusion, we evaluated the number of healthy follicles, corpus luteum, and cystic follicles, as well as the levels of testosterone, follicle-stimulating hormone (FSH), luteinizing hormone (LH), fasting blood glucose, fasting insulin, and insulin resistance. Moreover, we measured the serum levels of cholesterol, triglyceride (TG), high-density lipoprotein (HDL), and low-density lipoprotein (LDL). Liver function was determined by evaluating aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels.
Results
The number of corpora luteum, primordial, primary, secondary, and antral follicles significantly elevated in the PCOS-PDMSCs group versus the PCOS group. The number of cystic follicles significantly decreased in the PCOS-PDMSCs group. LH and testosterone levels decreased significantly, while FSH levels increased significantly in the PCOS-PDMSCs group. Fasting blood glucose levels, fasting insulin levels, and insulin resistance notably decreased in the PCOS-PDMSCs group. The lipid profile improved in the PCOS-PDMSCs group with significant cholesterol, LDL, and TG decreases and an increase in HDL. The PCOS-PDMSCs group exhibited marked decreases in the AST and ALT levels.
Conclusion
Our results suggest that PDMSCs are a potential treatment option for PCOS because they can effectively restore folliculogenesis, correct hormonal imbalances, modify metabolic/lipid profiles, and alleviate liver dysfunction in a rat model of PCOS. However, further research is needed to establish the safety and effectiveness of PDMSCs for treating PCOS.
WITHDRAWN: Analysis and Control of the Gearshift Process Based on a Dog Clutch Shiftability Model
Authors: Aljawabrah Ayham , Szabó Ádám , Lovas Laszlo 
Published: August 2024

Abstract

The full text of this preprint has been withdrawn by the authors as it was submitted and made public without the full consent of all the authors. Therefore, the authors do not wish this work to be cited as a reference. Questions should be directed to the corresponding author.
The Paradoxical Influence of Amerindian Ancestry on Clinical Outcomes in Crohn’s Disease and Ulcerative Colitis: Insights from a Chilean Cohort.
Authors: Perez-Jeldres Tamara , Bustamante María , Alvares Danilo , Alvarez-Lobos Manuel , Kalmer Lajos , Azocar Lorena , Melero Roberto , Ascui Gabriel , Aguilar Nataly , Estela Ricardo , Hernández-Rocha Cristian , Candia Roberto , González Mauricio , Silva Verónica , Vega Andrés De La , Arriagada Elizabeth , Serrano Carolina , Pávez-Ovalle Carolina , Quinteros Carol , Miquel Juan , Alex Di 
Published: August 2024

Abstract

Background. Research in Inflammatory Bowel Disease (IBD) assessing the genetic structure and its association with IBD phenotypes is needed, especially in IBD-underrepresented populations such as the South American IBD population. Aim. We examine the correlation between Amerindian ancestry and IBD phenotypes within a South American cohort and investigate the association between previously identified IBD risk variants and phenotypes.
Methods. We assessed the ancestral structure (IBD=291, Controls=51) to examine the association between Amerindian ancestry (AMR) and IBD variables. Additionally, we analyzed the influence of known IBD genetic risk factors on disease outcomes. We employed statistical tests to compare the different groups.
Results. The median distribution of global ancestry was 58% European, 39% Amerindian, and 2% African. There were no significant differences in IBD risk based on ancestry proportion between cases and controls. Ulcerative colitis (UC) patients diagnosed before age 40 had a higher median Amerindian ancestry proportion (39.9% versus 37.4%, P value = 0.01). Conversely, UC patients with prolonged clinical and endoscopy remission had a lower median Amerindian ancestry proportion (35% versus 39%, P value = 0.02). In the Crohn’s Disease (CD) group, the median Amerindian ancestry proportion was lower in the group with perianal disease (33.5% versus 39.5%, P value = 0.03). Only 6% of patients with resective surgery had a higher Amerindian ancestry proportion.
Conclusion. Our study highlights the impact of Amerindian ancestry on IBD phenotypes, suggesting a role for genetic and ancestral factors in disease phenotype. Further investigation is needed to unravel the underlying mechanisms driving these associations.
Spatial quantum-interference landscapes of exciton polaritons with multi-site-controlled quantum dots in extended cavity modes
Authors: Huang Jiahui , Miranda Alessio , Liu Wei , Cheng Xiang , Dwir Benjamin , Rudra Alok , Chang Kai-Chi , Kapon Eli , Wong Chee Wei 
Published: August 2024

Abstract

Emission properties of quantum light source can be modified through tailored photonic cavities via Purcell effect or strong light-matter interactions with various applications in integrated quantum photonics. The interacting excitonic and photonic states are core elements in the framework of cavity quantum electrodynamics. Successful characterization of subwavelength features of photonic modes from photonic crystal cavities constitutes basic building blocks for engineering the quantum photonic circuits. Potential trapping of polaritonic states has made great progress towards realizing efficient polaritonic devices. However, spatially features of excitonic states are rarely explored because extended wavefunction of quantum well excitons in the conventional quantum well – distributed Bragg reflector cavity system cannot be spatially distinguished from the photonic states. In this work, interactions of site-controlled quantum dots with a high-order cavity mode of an L7-type photonic crystal cavity with extended photonic states are spatially- and spectrally-resolved. We observed the first detuning-dependent spatial avoided crossing of the exciton-polaritons by polarized-imaging of the microphotoluminescence. Interestingly, such phenomenon is observed to be dependent on the position of the quantum dot in the cavity, with our precise control of the four quantum dot sites in the microcavity. The observed effect arises due to a unique quantum interference feature and can facilitate a deeper understanding of the spatial extent of a localized strongly-coupled excitonic state interacting with an extended photonic mode pattern. Based on our results, incorporating site-controlled quantum dots at prescribed locations in a photonic structure with tailored spatial patterns of photonic states can enable new integrated photonic devices with functionalities such as single-photon transport to remote locations for quantum information processing, quantum engineering, and quantum metrology.