bluuebunny/crossref_metadata_2025_split huggingface dataset:
μ2-Halogenokomplexe von N-Bromsuccinimid und N-Bromphthalimid. Die Kristallstrukturen von PPh4[X(N-Bromsuccinimid)2] und von PPh4[X(N-Bromphthalimid)2] mit X = CI und Br / μ2-Halogeno Complexes of N-Bromosuccinimide and N-Bromophthalimide. The Crystal Structures of PPh4 [X(N-Bromosuccinimide)2] and PPh4 [X(N-Brom ophthalimide)2] with X = Cl and Br
Authors: Ghassemzadeh Mitra , Harms Klaus , Dehnicke Kurt , Fenske Dieter 
Published: February 2015

The μ2-halogeno complexes PPh4[X(N-bromosuccinimide)2] and PPh4[X(N-bromophthali- mide)2] with X = Cl and Br have been prepared by reactions of N-bromosuccinimide and N-bromophthalimide, respectively, with the corresponding tetraphenylphosphonium halides PPh4X in acetonitrile solutions. The compounds form pale yellow crystal needles, which were characterized by IR spectroscopy and by crystal structure determinations.
PPh4[Cl(N-Bromosuccinimide)2] (1): Space group P21/n, Z = 4, structure solution with 2516 observed unique reflections, R = 0.040. Lattice dimensions at -25 °C: a = 1775.9(1), b = 764.3(1), c = 2341.7(2) pm, β = 101.84(1)°.
PPh4[Br(N-Bromosuccinimide)2] (2): Space group P21/n, Z = 4, structure solution with 5620 observed unique reflections, R = 0.061. Lattice dimensions at 20 °C: a = 1776.9(9), b = 762.2(3), c = 2331(1) pm, β = 103.02(3)°.
PPh4[Cl(N-Bromophthalimide)2] (3): Space group P1̅, Z = 4, structure solution with 3812 observed unique reflections, R = 0.039. Lattice dimensions at -50 °C: a = 918.5(2), b = 1115.0(3), c = 2584.4(5) pm, α = 88.22(3)°, β = 83.20(3)°, γ = 85.10(3)°.
PPh4[Br(N-Bromophthalimide)2] (4): Space group P1̅, Z = 2, structure solution with 3413 observed unique reflections, R = 0.044. Lattice dimensions at -50 °C: a = 1120.2(2), b = 1308.6(3), c = 1343.2(3) pm, α = 105.10(3)°, β = 104.16(3)°, γ = 92.99(3)°.
The structures of 1-4 consist of PPh4
+ ions, anions [X(N-bromosuccinimide)2]- and [X(N-bromophthalimide)2]-, respectively, in which the halide ions X- are coordinated by the bromine atoms of N-bromosuccinimide and N-bromophthalimide molecules, respectively. The bond angles Br···X···Br are 86.48(5)° for 1, 85.1(1)° for 2, 102.31(6)° and 93.61(6)° for 3, and 91.86(4)° for 4. The bond angles N-Br···X are nearly linear.
Beiträge zur Chemie des 4,5-Benzo-3-methyl-1,3,2-oxazaphosphorinan- 6-on Ringsystems: Röntgenstrukturanalysen an einem Bis(2-chlorethyl)amino- und einem Acetamido-substituierten Derivat / Chemistry of the 4,5-Benzo-3-methyl-1,3,2-oxazaphosphorinan-6-one Ring System: X-Ray Crystal Structure Analysis of a Bis(2-chloroethyl)amino- and of an Acetamido-Substituted Derivative
Authors: Fischer Axel , Neda Ion , Kaukorat Thomas , Sonnenburg Ralf , Jones Peter G. , Schmutzler Reinhard 
Published: February 2015

Abstract
The reaction of 4,5-benzo-2-chloro-3-methyl-1,3,2-oxazaphosphorinan-6-one 1 with 1,2-bis- (trimethylsiloxy)ethane led to the bisphosphoryl species 2a and to the isomeric bisphosphite derivative 2b. The reaction of 1 with heptamethyldisilazane furnished the expected diphos­phorus compound 3, with two λ3P(III) atoms linked by a methylamino group. Substitution of the chlorine atom of 1 by the 2-chloroethylamino and bis(2-chloroethyl)amino group led to the oxazaphosphorinanones 4 and 6. By oxidation of 4 with the hydrogen peroxide/urea 1:1-adduct, the phosphoryl compound 5 was formed. Oxidation of 4,5-benzo-2-diethyl- amino-3-methyl-1,3,2-oxazaphosphorinan-6-one 7 [1] with hydrogen peroxide, sulfur and se­lenium led to the corresponding phosphoryl, thiophosphoryl and selenophosphoryl com­pounds 8-10. Analogously, the reaction of the dimethylamino- and acetamido-substituted derivatives 11 and 13 [1] with elemental sulfur furnished the thiophosphoryl compounds 12 and 14. X-ray crystal structure determinations of 4 and 14 confirmed the molecular structures, proposed in accord with NMR spectroscopic and mass spectrometric data. The heterocyclic rings are essentially planar. In 14 a hydrogen bond N-H···O (amide) is observed.
Isolierung von Venturicidin X, dem Aglycon der Venturicidine A und B aus Streptomyceten / Isolation of Venturicidin X, the Aglycon of Venturicidines A and B from Streptopyces sp
Authors: Laatsch Hartmut , Kellner Michael , Lee Yong-Se , Wolf Gerhard 
Published: February 2015

Abstract
Venturicidin X (la ), the aglycon of the venturicidins A (1b) and B (1c) was isolated for the first time as a natural product from an unidentified Streptomyces sp. Venturicidin X (1a) is highly active against a broad spectrum of plant pathogenic fungi.
Ein neues Carbonat mit Baylissit-Struktur: Rb2[Mg(CO3)2(H2O)4] / A New Carbonate with Baylissite Structure: Rb2[Mg(CO3)2(H2O)4]
Authors: Zheng Yue Qing , Adam Arnold 
Published: February 2015

Abstract
The new complex carbonate Rb2[Mg(CO3)2(H2O))4] crystallizes in the Baylissite-type structure with a = 1130,4(3), b = 641,9(1), c = 703,3(2) pm, β = 99,62(1)°, VEZ = 503,2(2), space group P21/n (No. 14) and Z = 2. In comparison with the isostructural potassium compound the cell dimensions increase in b- and c- and decrease in a-direction. This effect depends on the greater coordination number of Rb+ and the rigidity of strong hydrogen bonds. The carbonate anion exhibits significant deviations from D3h-symmetry (C -O: 127,1(5)-130,2(5) pm, ∠ O - C - O: 117,9(4)-121,1(3)°).
Heterometallische Verbindungen. Darstellung und Strukturen einiger Co(III)-Komplexe mit CrO4
2--Liganden / Heterometallic Compounds. Preparation and Structures of Some Co(III) Complexes with CrO4
2- Ligands
Authors: Brüggemann Ricardo Catasus y , Thewalt Ulf 
Published: February 2015

Heteronuclear complexes containing Co(III) and Cr(VI) are formed on reaction of [Co(en)2(OH)(OH2)]2+or [Co(tren)(OH)(OH2)]2+ cations with CrO4
2- .Two types of com­plexes were isolated:
1.Complexes with two trans chromato ligands at Co; namely Li[Co(en)2(CrO4)2]·5H2O (1a) and K[Co(en)2(CrO4)2](1b).
2.Complexes having a cyclic structure with two CrO4 bridges between two cis-Co(en)2 or Co(tren) units, namely [Co2(en)4(CrO4)2]Cl2 (2a), [Co2(en)4(CrO4)2]Br2 (2b)and [Co2(tren)2(CrO4)2](ClO4)2(3).
The molecular structures have been confirmed by X-ray methods. The molecular confor­mations adopted by the complexes in the solid state are stabilized by intramolecular hydro­gen bonds.
Zur Festphasenpeptidsynthese des Makrophagen-migrationsinhibierenden Faktors der Maus (mMIF): Ein Vergleich verschiedener Syntheseansätze zur Darstellung der schwierigen C-terminalen Sequenz mMIF(93-115)/ Solid Phase Peptide Synthetic Approaches to Mouse Macrophage Migration Inhibitory Factor (mMIF): Comparison of Different Strategies Producing the C-Terminal Difficult Sequence Peptide mMIF (93-115)
Authors: Kaiser Thomas , Voelter Wolfgang 
Published: February 2015

Abstract
From solid phase peptide synthetic approaches of mMIF(93-115) the C-terminal sequence turned out to be a typical „difficult sequence“ peptide. Various stepwise syntheses were performed with different resins and coupling reagents. The Peptide was synthesized in 90% yield by solid phase fragment condensation of protected mMIF(93-108) to mMIF(109-115) ‘2-Chlorotrityl’ resin bound.
Unsymmetrische BN2
3--Ionen in den Strukturen von Ca2ClBN2 und Sr2ClBN2 / Unsymmetric BN2
3--Ions in the Structures of Ca2ClBN2 and Sr2ClBN2
Authors: Reckeweg Olaf , Meyer H.-Jürgen 
Published: February 2015

Abstract
The new compounds Ca2ClBN2 (1) and Sr2ClBN2 (2) were prepared from the respective metal, its dihalide and h-BN in sealed tantalum ampoules at 1200 °C. The crystals obtained were transparent yellow (1) and blue (2), respectively. The crystal structures were determined from single crystal X-ray data. Ca2ClBN2 and Sr2ClBN2 are isotypic and crystallize in the orthorhombic space group Pnma (No. 62), Z = 4 (Ca2ClBN 2: a = 1166.7(2), b = 390.26(4), c = 899.8(1) pm, R1 = 0.043, wR2 = 0.115 for 554 independent reflections; Sr2ClBN2: a = 1242.8(1), b = 416.75(4), c = 920.8(1) pm, R1 = 0.031, wR2 = 0.054 for 662 independent reflections).
The structures contain two different layers of M2+, Cl- and BN2
3- alternating along the [010] direction. The bond angles N-B-N are 177.2(4)° for (1) and 176,6(5)° for (2), the bond distances of the BN2
3- ions are dB_ N1] = 134.6(5) pm for (1), 136,3(7) pm for (2) and dB_N2 = 132.4(5) pm for (1) and 131,3(7) pm for (2). The unsymmetric structure of the BN2
3- ion, as is manifested particularly in the Sr compound (2), is caused by the coordination of N1 to four cations while N2 is coordinated only to three.
Crystal and Molecular Structure of Methylpropylglyoxal Bis(amidinohydrazone) Sulphate Monohydrate
Authors: Koskinen Mikko , Mutikainen Ilpo , Koskinen Jere T. , Elo Hannu 
Published: February 2015

Abstract
A single-crystal X-ray diffraction study was performed on methylpropylglyoxal bis(amidinohydrazone) (M PGBG) sulphate monohydrate. The bis(amidinohydrazone) dication was found to exist exclusively in the form of the anti-anti isomer, with an all-trans configuration of the glyoxal bis(amidinohydrazone) chain, just as do the free base, the monocation and the dication of glyoxal bis(amidinohydrazone) and the dications of all mono-and dialkylglyoxal bis(amidinohydrazones) so far studied. MPGBG sulphate monohydrate crystallizes in the triclinic space group Pl̅ with unit cell parameters a = 8.860(2), b = 9.195(2), c = 10.788(2) Å, α = 73.71(3), β = 77.59(3), γ = 65.28(3)° and with Z = 2. When the structure is compared with that of propylglyoxal bis(amidinohydrazone) (PGBG) sulphate, an analogous compound that is devoid of the methyl group of MPGBG, a distinct difference can be observed regard­ing the conformation of the propyl side chain. In the MPGBG dication, the propyl group is directed away from the glyoxal bis(amidinohydrazone) chain, whilst in the case of the PGBG dication it is tangled around the glyoxal bis(amidinohydrazone) moiety. Whether this difference results from packing effects and related factors, or whether it is a result of a more fundamental difference between MPGBG and PGBG, remains to be studied. The observed difference may contribute to the biochemical differences between the two compounds.
Synthesis and Crystal Structure of Mn2(C2H5NH2)2Sb2S5 Exhibiting a Reversible Phase Transition
Authors: Schur Michael , Näther Christian , Bensch Wolfgang 
Published: February 2015

Abstract
Thioantimonates, Solvothermal Synthesis, Chalcogenides The reaction of elemental manganese, antimony and sulfur with ethylamine under mild solvothermal conditions yielded a thioantimonate(III) with composition Mn2(EA)2Sb2S5 (EA = C2H5NH2) that is a new member of a series of polymeric manganese thioantimo-nates(III). The structure of the title compound consists of layers of a neutral mesh-like Mn2Sb2S5 framework. The ethylamino ligands coordinated to the Mn centres separate the sheets and fill the voids within the layers formed by the interconnection of Mn2Sb2S4 hetero-cubane like building blocks. Below 273 K a reversible phase transition occurs, which is accom­panied by a doubling of the crystallographic a-axis.
Dimeres Di(N-lithium–tert–butylamino)bis(dimethylamino)silan - [Si(N(CH3)2)2(NLiC(CH3)3)2]2 – Darstellung und Kristallstruktur / Dimeric Di(N -lithio-tert-butylamino)bis(dimethylamino)silane - [Si(N(CH3)2)2(NLiC(CH3)3)2]2 – Synthesis und Crystal Structure
Authors: Engering Josef , Peters Eva-Maria , Jansen Martin 
Published: February 2015

Abstract
[Si(N(CH3)2)2(NLiC(CH3)3)2]2 results from the reaction of silicon tetrachloride with excess terf-butylamine, followed by halogen substitution with LiN(CH3)2, and treatment with n-butyllithium in hexane. The title compound, found to be dimeric in the solid state, was characterised by single crystal X-ray diffraction (triclinic, Pi , a = 10.208(2), b = 12.140(2), c = 15.658(3) Å , a = 79.02(3), ß = 82.80(3), γ = 67.19(3)°, Z = 2, C24H60Li4N8Si2 ), and by solid state and solution NMR-spectroscopy and mass spectrometry.
Oxovanadium(IV), Nickel(II) and Palladium(II) Complexes of Tridentate Salicylaldiminates Derived from 2,4-Di-ter-butyl-6-aminophenol
Authors: Kasumov Veli T. 
Published: February 2015

Abstract
Several new binuclear nickel(II), oxovanadium(IV) and palladium(II) complexes (MLX) of tridentate salicylaldimines (LXH2) obtained from substituted salicylaldehydes and 2,4-di-tert-butyl-6-aminophenol, as well as mononuclear nickel(II) and oxovanadium(IV), MQx nH2O, complexes with hydrogenated LX H2 ligands (QXH2) have been prepared and their spectroscopic, magnetic and catalytic activity (for PdLx) have been investigated. NiLx and VOLx complexes when dissolved in pyridine, take up three or two pyridine molecules to form six coordinated complexes, respectively. The Ni(II) and VO(IV) complexes obtained from QXH2 can be formu­lated as NiQx-3H2O and VOQx H2O. All VO(IV) complexes have been characterized by ESR parameters. It has been found that some PdLx complexes without any preliminary activation, in EtOH, THF and DMF exhibit high catalytic activity in the hydrogenation of nitrobenzene or cyclohexene at room temperature and at 30 -40 °C under 760 torr H2. When this reaction has been carried out in the ESR cavity at room temperature the triplet of 12 line multiplets due to the nitroxyl type coordinated radical (g = 2.013, AN = 10 G, AH = 0.8 G) was detected.
Quassinoids and Other Constituents from Picrasma crenata
Authors: Krebs H. C. , Schilling P. J. , Wartchow R. , Bolte M. 
Published: February 2015

Abstract
16-β-O-methylneoquassin and 16-β-O-ethylneoquassin, and four known quassi­ noids have been isolated together with coniferyl aldehyde, coniferin, cantin-6-one, 4,5-di-methoxycantin-6-one and (+)-neo-olivil from the wood of Picrasma crenata. Their structures were determined on basis of spectroscopic and X-ray analysis.
α-Dicarbonylmonophenylhydrazone als Nucleophile und Nachbargruppen / α-Dicarbonylmonophenylhydrazones as Nucleophiles and Neighbouring Groups
Authors: Möhrle Hans , Keller Georg 
Published: February 2015

Abstract
The α-dicarbonylmonophenylhydrazones 1 and 8 do not react as simple ,,CH-acidic compounds“ in the Mannich condensation reaction. In a concerted reaction with aminals in absolute dioxane they give rise to the products 5a-e and 10a-e with better practicability and much higher yields compared with the conventional method. The formal Mannich bases 5a/5b/5d and 10a/10b/10d with a cyclic amine part show in the dehydrogenation, using mercury- EDTA , a neighbouring group participation of the phenylhydrazono moiety yielding the corresponding lactams. With 5c only cyclization occurs leading to 1,2,4-triazine 19 in low yield, while 10c shows no dehydrogenation but an amine elimination to the vinyl-azo com pound 21 with consecutive cycloaddition leading to the 1,2-diazine 23.
Ba16Nb5N19 - A Nitridoniobate(V) Containing Isolated [NbN4]7- and [Nb2N7]11- Units
Authors: Höhn Peter , Kniep Rüdiger 
Published: February 2015

Abstract
Ba16NbsN19 was synthesized by reaction of Ba with Nb under nitrogen at ambient pressure at 1223 K. The refined crystal structure was solved in the space group P1̄ (no. 2), Z = 2, with the lattice constants a = 1099.33(3), b = 1140.41(15), c = 1622.06(6) pm, α = 72.197(2)°, β = 59.949(1)°, γ = 82.243(2)° and R1 = 0.058, wR2 = 0.088. The crystal structure contains both isolated [NbN4]7- as well as dimeric units [Nb2N7 ]11- . Together with the Ba2+ ions the compound has to be regarded as Ba16 [NbN4]3[Nb2N7 ].
New Hydrazinium Salts of 5,5'-Azotetrazolate
Authors: Hammerl Anton , Holl Gerhard , Kaiser M. , Klapötke Thomas M. , Mayer Peter , Nöth Heinrich , Piotrowski Holger , Suter Max 
Published: February 2015

Abstract
Salts of the 5,5′-azotetrazolate dianion with several different hydrazinium cations were pre­ pared. The compounds were characterized by elemental analysis, vibrational spectroscopy (IR, Raman) and multinuclear NMR spectroscopy (1H, 13C, 14 N). The crystal structures of the di-tert-butylhydrazinium, the ethylenedihydrazinium, the diguanidinium and the bis-triamino-guanidinium azotetrazolate were determined. The thermal, shock and friction sensitivities of all compounds were investigated and their explosion products were analysed. For the 5,5′-azotetr-azolate dianion the structure was calculated with density functional theory (B3-LYP). An NBO analysis was performed for the 5,5′-azotetrazolate dianion in order to understand the charge distribution of the dianion.
Thermochemische Untersuchungen zu den Systemen SE2O3-SeO2. II. Samariumselenoxide auf dem Schnitt Sm2O3-SeO2 / Thermochemical Investigations of Systems SE2O3-SeO2. II. Samarium Selenium Oxides on the Line Sm2O3-SeO2
Authors: Oppermann H. , Zhang-Preβe M. 
Published: February 2015

Abstract
The pure ternary phases on the line Sm2O3-SeO2: Sm2SexO3+2x in thermodynamical equilibri­um have been synthesizied by solid state reactions and characterized by X-ray powder diffrac­tion, IR spectroscopy and DSC measurements. The existence of two new phases Sm2Se1,5O6 and Sm2Se4O11 was demonstrated besides the known phases Sm2Se3,5O10, Sm2Se3O9 and Sm2SeO5. The thermal decomposition properties of all compounds have been determined by total pressure measurements and the thermodynamical data of the compounds have been derived from their decomposition function and Cp-values. The phase diagram and the phase barogram have been estabilished using the results of DSC and total pressure measurements.
Synthesis and Crystal Structure of [Bis(N-oxo-2-acetylpyridine 4N-Methylthiosemicarbazone)zinc(II)] Monohydrate
Authors: Castiñeiras Alfonso , Domínguez Ricardo , Bordinhão Jairo , de Oliveira Julieta Saldanha , Bortoluzzi Adaílton João , Hörner Manfredo 
Published: February 2015

Abstract
The reaction of zinc(II) acetate dihydrate and the tetra-dentate N-Oxo-2-acetylpyridine 4N-methylthiosemicarbazone (H4MLO) produces the novel complex [Zn(C9H11N4OS)2·H2O] (1). The complex crystallizesoin the orthorhombic space group Pbca with a = 15.871(3), b =16.890(3), c = 17.189(3) Å ,V - 4608(1) Å3, Z = 8 . The Zn(II) ion is tetra-coordinated via the thiolate sulfur atom and the azomethine nitrogen atom of two deprotonated ligands. In the solid state, 1 is polymerized via hydrogen bonds with a water molecule of crystallization.
Carbonyl(diphenylcyclopentadienyl)-und Carbonyl(tetraphenylcyclopentadienyl)rhodium(I) Komplexe/Carbonyl(diphenylcyclopentadienyl)-and Carbonyl(tetraphenylcyclopentadienyl)rhodium(I) Complexes
Authors: Schumann Herbert , Stenz Susanne 
Published: February 2015

Abstract
[Rh(CO)2Cl]2 reacts with 1,3-diphenylcyclopentadienyl sodium or tetraphenylcyclopentadienyl sodium with formation of (1,3 -Ph2C5H3)Rh(CO)2 (1) or (C5HPh4)Rh(CO)2 (2), respectively. The reaction of 1 or 2 with PPh3 yields the corresponding carbonyl-(cyclopentadienyl)(triphenylphosphane)rhodium complexes (1,3 -Ph2C5H3)Rh(CO)(PPh3) (3) or (C5HPh4)Rh(CO)(PPh3) (4). The 1H and 1C reported and discussed.
Adaptive Evolution of Genes Involved in the Regulation of Germline Stem Cells inDrosophila melanogasterandD. simulans
Authors: Flores Heather A , DuMont Vanessa L Bauer , Fatoo Aalya , Hubbard Diana , Hijji Mohammed , Barbash Daniel A , Aquadro Charles F 
Published: February 2015

AbstractPopulation genetic and comparative analyses in diverse taxa have shown that numerous genes involved in reproduction are adaptively evolving. Two genes involved in germline stem cell regulation, bag of marbles (bam) and benign gonial cell neoplasm (bgcn), have been shown previously to experience recurrent, adaptive evolution in both Drosophila melanogaster and D. simulans. Here we report a population genetic survey on eight additional genes involved in germline stem cell regulation in D. melanogaster and D. simulans that reveals all eight of these genes reject a neutral model of evolution in at least one test and one species after correction for multiple testing using a false-discovery rate of 0.05. These genes play diverse roles in the regulation of germline stem cells, suggesting that positive selection in response to several evolutionary pressures may be acting to drive the adaptive evolution of these genes.
Defining the Functions of Public Health Governance
Authors: Carlson Valeria , Chilton Marita J. , Corso Liza C. , Beitsch Leslie M. 
Published: February 2015

We conducted a literature review in 2011 to determine if accepted governance functions continue to reflect the role of public health governing entities. Reviewing literature and other source documents, as well as consulting with practitioners, resulted in an iterative process that identified 6 functions of public health governance and established definitions for each of these: policy development; resource stewardship; continuous improvement; partner engagement; legal authority; and oversight of a health department. These functions provided context for the role of governing entities in public health practice and aligned well with existing public health accreditation standards. Public health systems research can build from this work in future explorations of the contributions of governance to health department performance.
New Perspectives on the “Silo Effect”: Initial Comparisons of Network Structures Across Public Health Collaboratives
Authors: Bevc Christine A. , H. Retrum Jessica , M. Varda Danielle 
Published: February 2015

Objectives. We explored to what extent “silos” (preferential partnering) persist in interorganizational boundaries despite advances in working across boundaries. We focused on organizational homophily and resulting silo effects within networks that might both facilitate and impede success in public health collaboratives (PHCs). Methods. We analyzed data from 162 PHCs with a series of exponential random graph models to determine the influence of uniform and differential homophily among organizations and to identify the propensity for partnerships with similar organizations. Results. The results demonstrated a low presence (8%) of uniform homophily among networks, whereas a greater number (30%) of PHCs contained varying levels of differential homophily by 1 or more types of organization. We noted that the higher frequency among law enforcement, nonprofits, and public health organizations demonstrated a partner preference with similar organizations. Conclusions. Although we identified only a modest occurrence of partner preference in PHCs, overall success in efforts to work across boundaries might be problematic when public health members (often leaders of PHCs) exhibit the tendency to form silos.
Network Interventions on Physical Activity in an Afterschool Program: An Agent-Based Social Network Study
Authors: Zhang Jun , Shoham David A. , Tesdahl Eric , Gesell Sabina B. 
Published: February 2015

Objectives. We studied simulated interventions that leveraged social networks to increase physical activity in children. Methods. We studied a real-world social network of 81 children (average age = 7.96 years) who lived in low socioeconomic status neighborhoods, and attended public schools and 1 of 2 structured afterschool programs. The sample was ethnically diverse, and 44% were overweight or obese. We used social network analysis and agent-based modeling simulations to test whether implementing a network intervention would increase children’s physical activity. We tested 3 intervention strategies. Results. The intervention that targeted opinion leaders was effective in increasing the average level of physical activity across the entire network. However, the intervention that targeted the most sedentary children was the best at increasing their physical activity levels. Conclusions. Which network intervention to implement depends on whether the goal is to shift the entire distribution of physical activity or to influence those most adversely affected by low physical activity. Agent-based modeling could be an important complement to traditional project planning tools, analogous to sample size and power analyses, to help researchers design more effective interventions for increasing children’s physical activity.