bluuebunny/crossref_metadata_2025_split huggingface dataset:
Remembering the Borderlands: Traditional Music and the Post-Frontier in Aisén, Chile
Authors: Robinson Gregory J. 
Published: September 2013

Abstract
In the Region of Aisén, in Chilean Patagonia, musicians claim Argentine popular music from the early twentieth century as regional tradition, and call on it to express local identifications and Chilean patriotism. This seemingly incongruous form of traditionalism is rooted in narratives of Aisén’s early history, when Chilean settlers depended on Argentina for their survival in marginal, frontier circumstances. This article introduces the concept of the "post-frontier" to explain the position from which residents of Aisén claim this music as their own. This research opens new territory in the study of transnational music, tracing the various ways in which temporality acts upon and within notions of regional identity, national belonging, and transnational affinity.
Traces of the Individual in Prehistory
Authors: Watts Joshua 
Published: September 2013

AbstractThere is considerable and largely untapped potential in individual-scale research in the discipline of archaeology. Innovative methods described in this article were developed to identify the work of individual prehistoric flintknappers. Theoretically, the approach was informed by previous researchers' discussions of technological style and utilizes an individual- or nano-scale focus for that concept. New analytical methods were then used to investigate individual flintknappers' participation in the community organization of the prehistoric eastern Tonto Basin, Arizona. Specifically, small triangular stone projectile points (n = 149) collected from Roosevelt phase (A.D. 1275–1325) sites were analyzed to inform an assessment of the spatial distribution of individuals' handiwork in late prehistoric multi-site settlements. This research illustrates how improved individual-scale techniques may provide new insight on topics of considerable interest to archaeologists. For the Tonto Basin case, this project offers a new perspective on the integration of immigrants into local systems and the strength of community ties across natural barriers such as the Salt River during the Roosevelt phase.
Piezoresistive behavior of graphene nanoplatelets/carbon black/silicone rubber nanocomposite
Authors: Cai Wenting , Huang Ying , Wang Dayue , Liu Caixia , Zhang Yugang 
Published: September 2013

ABSTRACTSilicon rubber (SR) filled with carbon black (CB) and carbon black (CB)/graphene nanoplatelets (GNPs) hybrid fillers are synthesized via a liquid mixing method. The effects of filler type on the electrical properties and piezoresistive properties (near the region of the percolation) of the conductive SR composites are studied. It is suggested that the conductivity of the composite filled with CB/GNPs hybrid fillers in the mass ratio of 2 : 4 is much higher than that in other ratio. Percolation threshold for CB/GNPs/SR is found to be 0.18 volume fractions lower than CB/SR. Moreover, force rang and linearity of GNPs/CB/SR is higher than CB alone filling system. And the repeatability of the GNPs/CB/SR composites is better than CB/SR. Not repetitive index () of them is 0.1 and 0.18, respectively. The results suggest that the GNPs/CB/SR composites provide a new route toward fabrication of flexible piezoresistive sensors with high performance. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2014, 131, 39778.
Heterodinuclear Lanthanoid‐Containing Polyoxometalates: Stepwise Synthesis and Single‐Molecule Magnet Behavior
Authors: Sato Rinta , Suzuki Kosuke , Sugawa Midori , Mizuno Noritaka 
Published: September 2013

AbstractPolyoxometalates (POMs) with heterodinuclear lanthanoid cores, TBA8H4[{Ln(μ2‐OH)2Ln′}(γ‐SiW10O36)2] (LnLn′; Ln=Gd, Dy; Ln′=Eu, Yb, Lu; TBA=tetra‐n‐butylammonium), were successfully synthesized through the stepwise incorporation of two types of lanthanoid cations into the vacant sites of lacunary [γ‐SiW10O36]8− units without the use of templating cations. The incorporation of a Ln3+ ion into the vacant site between two [γ‐SiW10O36]8− units afforded mononuclear Ln3+‐containing sandwich‐type POMs with vacant sites (Ln1; TBA8H5[{Ln(H2O)4}(γ‐SiW10O36)2]; Ln=Dy, Gd, La). The vacant sites in Ln1 were surrounded by coordinating WO and LnO oxygen atoms. On the addition of one equivalent of [Ln′(acac)3] to solutions of Dy1 or Gd1 in 1,2‐dichloroethane (DCE), heterodinuclear lanthanoid cores with bis(μ2‐OH) bridging ligands, [Dy(μ2‐OH)2Ln′]4+, were selectively synthesized (LnLn′; Ln=Dy, Gd; Ln′=Eu, Yb, Lu). On the other hand, La1, which contained the largest lanthanoid cation, could not accommodate a second Ln′3+ ion. DyLn′ showed single‐molecule magnet behavior and their energy barriers for magnetization reversal (ΔE/kB) could be manipulated by adjusting the coordination geometry and anisotropy of the Dy3+ ion by tuning the adjacent Ln′3+ ion in the heterodinuclear [Dy(μ2‐OH)2Ln′]4+ cores. The energy barriers increased in the order: DyLu (ΔE/kB=48 K)<DyYb (53 K)<DyDy (66 K)<DyEu (73 K), with an increase in the ionic radii of Ln′3+; DyEu showed the highest energy barrier.
A failure analysis of invasive breast cancer: Most deaths from disease occur in women not regularly screened
Authors: Webb Matthew L. , Cady Blake , Michaelson James S. , Bush Devon M. , Calvillo Katherina Zabicki , Kopans Daniel B. , Smith Barbara L. 
Published: September 2013

BACKGROUNDMortality reduction from mammographic screening is controversial. Individual randomized trials and meta‐analyses demonstrate statistically significant mortality reductions in all age groups invited to screening. In women actually screened, mortality reductions are greater. Individual trials and meta‐analyses show varying rates of mortality reduction, leading to questions about screening's value and whether treatment advances have diminished the importance of early detection. This study hypothesized that breast cancer deaths predominantly occurred in unscreened women.METHODSInvasive breast cancers diagnosed between 1990 and 1999 were followed through 2007. Data included demographics, mammography use, surgical and pathology reports, and recurrence and death dates. Mammograms were categorized as screening or diagnostic based on absence or presence of breast signs or symptoms, and were substantiated by medical records. Breast cancer deaths were defined after documentation of prior distant metastases. Absence of recurrent cancer and lethal other diseases defined death from other causes.RESULTSInvasive breast cancer failure analysis defined 7301 patients between 1990 and 1999, with 1705 documented deaths from breast cancer (n = 609) or other causes (n = 905). Among 609 confirmed breast cancer deaths, 29% were among women who had been screened (19% screen‐detected and 10% interval cancers), whereas 71% were among unscreened women, including > 2 years since last mammogram (6%), or never screened (65%). Overall, 29% of cancer deaths were screened, whereas 71% were unscreened. Median age at diagnosis of fatal cancers was 49 years; in deaths not from breast cancer, median age at diagnosis was 72 years.CONCLUSIONSMost deaths from breast cancer occur in unscreened women. To maximize mortality reduction and life‐years gained, initiation of regular screening before age 50 years should be encouraged. Cancer 2014;120:2839–2846. © 2013 American Cancer Society.
Stereoselective Formation of Z‐ or E‐Vinyl Thioethers from Arylthiols and Acetylenes under Transition‐Metal‐Free Conditions
Authors: Liao Yunfeng , Chen Shanping , Jiang Pengcheng , Qi Hongrui , Deng Guo‐Jun 
Published: September 2013

AbstractVinyl sulfide formation with good yield and high regio‐ and stereoselectivities from thiols and acetylenes under transition‐metal‐free conditions is described. Potassium phosphate was used as an effective additive to enhance the reaction yield and selectivity. Z‐Vinyl sulfides were predominately formed in the presence of potassium phosphate, whereas E‐vinyl sulfides were formed under solvent‐ and base‐free conditions.
Synthesis of Linear Aza and Thio Analogues of Acetogenins and Evaluation of Their Cytotoxicity
Authors: Villo Piret , Toom Lauri , Eriste Elo , Vares Lauri 
Published: September 2013

AbstractWe report the stereoselective synthesis of thio and aza analogues of Annonaceous acetogenins. The synthetic route allows easy variation of the stereochemistry and of the thio‐ and aza‐fragments. Kinetic resolution of terminal bis‐epoxides was used to set two remote stereocentres with high enantio‐ and diastereoselectivities in one step. The cytotoxicity of the analogues was assessed using the HeLa cell line.
The effect of lisdexamfetamine dimesylate on body weight, metabolic parameters, and attention deficit hyperactivity disorder symptomatology in adults with bipolar I/II disorder
Authors: McIntyre Roger S. , Alsuwaidan Mohammad , Soczynska Joanna K. , Szpindel Isaac , Bilkey Timothy S. , Almagor Doron , Woldeyohannes Hanna O. , Powell Alissa M. , Cha Danielle S. , Gallaugher Laura Ashley , Kennedy Sidney H. 
Published: September 2013

ObjectivesWe primarily sought to determine the effect of adjunctive lisdexamfetamine dimesylate (LDX) on anthropometric and metabolic parameters. Our secondary aim was to evaluate the effect of LDX on attention deficit hyperactivity disorder (ADHD) symptom severity in adults with bipolar I/II disorder.MethodsForty‐five stable adults (i.e., non‐rapid cycling, absence of clinically significant hypo/manic symptoms) with bipolar I/II disorder and comorbid ADHD were enrolled in a phase IV, 4‐week, flexible dose, open‐label study of adjunctive LDX. All subjects were initiated at 30 mg/day of adjunctive LDX for the first week with flexible dosing (i.e., 30–70 mg/day) between weeks 2 and 4.ResultsOf the 45 subjects enrolled, 40 received adjunctive LDX (mean dose = 60 ± 10 mg/day). A statistically significant decrease from baseline to endpoint was evident in weight (p < 0.001), body mass index (p < 0.001), fasting total cholesterol (p = 0.011), low density lipoprotein cholesterol (p = 0.044), high density lipoprotein cholesterol (p = 0.015) but not triglycerides, or blood glucose. Significant reductions were also observed in leptin (p = 0.047), but not in ghrelin, adiponectin, or resistin levels. Diastolic blood pressure and pulse increased significantly over time but on average remained within the normal range (p < 0.001). There was a significant reduction from baseline to endpoint in the total score of the ADHD Self‐Report Scale. Significant improvement from baseline to endpoint was also observed in the Montgomery–Åsberg Depression Rating Scale total score as well as the Clinical Global Impression Severity and Improvement score.ConclusionsShort‐term adjunctive LDX treatment was well tolerated by this sample of adults with stable bipolar I/II disorder. Lisdexamfetamine dimesylate offered beneficial effects on body weight, body mass index and several metabolic parameters. In addition to demonstrating short‐term (i.e., 4 weeks) safety and tolerability, beneficial effects of LDX were also observed in mitigating depressive and ADHD symptom severity. Copyright © 2013 John Wiley & Sons, Ltd.
Effect of food on the pharmacokinetics of lurasidone: results of two randomized, open‐label, crossover studies
Authors: Preskorn Sheldon , Ereshefsky Larry , Chiu Yu‐Yuan , Poola Nagaraju , Loebel Antony 
Published: September 2013

ObjectiveThis study aimed to investigate the effect of prandial status and caloric and fat composition of meals on the pharmacokinetics of lurasidone.MethodsTwo randomized, open‐label, crossover studies were conducted in clinically stable adults with schizophrenia or schizoaffective disorder. Study 1 (n = 16) evaluated the effect of fasting and three meal types (100 kcal/medium fat, 200 kcal/medium fat, and 800–1000 kcal/high fat), and Study 2 (n = 26) evaluated the effect of fasting and five meal types (350 kcal/high fat, 500 kcal/low fat, 500 kcal/high fat, 800–1000 kcal/low fat, and 800–1000 kcal/high fat) on the bioavailability of lurasidone. Subjects received lurasidone 120 mg once daily. Maximum serum concentration (Cmax) and area under the serum concentration–time curve over the dosing interval (AUC0–tau) were determined on Day 5 for each meal type.ResultsIn Study 1, the geometric mean Cmax in the fasted state was 56.7 ng/mL compared with 123.0 ng/mL for the 800‐ to 1000‐kcal meal; mean AUC0–tau was 360.0 versus 752.4 ng·h/mL (both p < 0.001). Lurasidone exposure following meals containing 100 and 200 kcal was substantially lower than with meals containing 800–1000 kcal. In Study 2, the geometric mean Cmax was 52.9 ng/mL in the fasted state, 161 ng/mL for the 350‐kcal/high‐fat meal, 135 ng/mL for the 500‐kcal/high‐fat meal, and 131 ng/mL for the 800‐ to 1000‐kcal/high‐fat meal; mean AUC0–tau was 390, 743, 727, and 769 ng·h/mL, respectively. For all comparisons, the 90% confidence interval of the fed to fasted ratios indicated nonequivalence. Lurasidone exposure was similar following meals containing 350–1000 kcal and was independent of fat content.ConclusionLurasidone should be administered with food—at least 350 kcal—to ensure maximum exposure. Copyright © 2013 John Wiley & Sons, Ltd.
Assessing the influence of afforestation with Eucalyptus globulus on hydrological response from a small catchment in northwestern Spain using the HBV hydrological model
Authors: Rodriguez Suarez J. A. , Diaz‐Fierros F. , Perez R. , Soto B. 
Published: September 2013

AbstractLand use change as conversion pasture to forest produces several changes on hydrological cycle. In this paper, we analyse the effects on stream discharge of afforestation of a small watershed devoted to pasture using the HBV hydrological model.Streamflow data obtained over the first 10 years after planting were employed to evaluate the capacity of HBV model to simulate hydrological behaviour of catchment after afforestation. Obtained results indicate that the estimation of streamflow was accurate as reflected by statistics (R2 = 0.90, NSC = 0.89 and PBIAS = 0.34).Afterwards, streamflow under pasture land use (if afforestation had not occurred) was simulated using hydrometeorological data collected during the period of study and model parameters optimized previously, together with two parameters, pcorr and cevpfo, that were adjusted for pasture conditions.The HBV model results indicate that afforestation produced a water yield reduction around 2000 mm (22% of total stream discharge) during the first 10 years of planting growth. The differences between forest and pasture land cover are increasing in all seasons year by year. The greatest streamflow reduction was observed in wet period (autumn and winter) with 76% of total reduction. In summer, streamflow reduction represents only 3% of total, however, represents 24.7% of discharge in this season.Streamflow reduction was related to increase of rainfall interception (mainly in wet periods) and the increase of evapotranspiration by plantation in dry periods. Copyright © 2013 John Wiley & Sons, Ltd.
Nighttime ionospheric enhancements induced by the occurrence of an evening solar eclipse
Authors: Chen Gang , Qi Hao , Ning Baiqi , Zhao Zhengyu , Yao Ming , Deng Zhongxing , Li Ting , Huang Shuo , Feng Wenchao , Wu Jianhua , Wu Chen 
Published: September 2013

AbstractThe solar eclipse on 15 January 2010 traversed Asia and completed its travel on the Shandong Peninsula in China at sunset. Two vertical incidence ionosondes at Wuhan and Beijing and the oblique incidence ionosonde network in North China were implemented to record the ionospheric response to the solar eclipse. Following the initial electron density decrease caused by the eclipse, the ionosphere was characterized by a strong premidnight enhancement, and a subsequent ionospheric decay, and a ~10 h later postmidnight enhancement. Neither geomagnetic disturbance occurred during the eclipse day nor did obvious nighttime peak appear for the 10 day mean of the F2‐layer critical frequency (foF2). The electron density profilogram of the Beijing ionosonde indicates that the two enhancements were the result of the plasma flux downward from the top ionosphere, possibly due to the steep decrease of the ionospheric electron density and plasma temperature during the solar eclipse. The two‐dimensional differential foF2 maps present the regional variations of the nighttime electron density peaks and decay. Both the pre‐ and postmidnight enhancements initially appeared in a belt almost in parallel with the eclipse track and then drifted southward. The different magnitudes of greatest eclipse in the umbra and outside tend to account for the different occurrence times of the plasma flux. The ionospheric decay following the premidnight enhancement is also considered as a consequence of the eclipse shade.
Do organizations spend wisely on employees? Effects of training and development investments on learning and innovation in organizations
Authors: Sung Sun Young , Choi Jin Nam 
Published: September 2013

SummaryThe present study examines the effects of training and development on organizational innovation. We specifically suggest that the training and development investments of an organization affect its innovative performance by promoting various learning practices. We empirically tested our hypothesis by using time‐lagged, multi‐source data collected from 260 Korean companies that represent diverse industries. Our analysis showed that corporate expenditure for internal training predicts interpersonal and organizational learning practices, which, in turn, increase innovative performance. The data also revealed that the positive relationship between interpersonal and organizational learning practices and innovative performance is stronger within organizations that have stronger innovative climates. By contrast, investment in employee development through financial support for education outside an organization poses a significant negative effect on its innovative performance and no significant effect on learning practices. The present study provides a plausible explanation for a mechanism through which the investment of an organization in employees enhances its innovative performance. Copyright © 2013 The Authors.Journal of Organizational Behaviorpublished by John Wiley & Sons, Ltd.
Development of QSAR‐Improved Statistical Potential for the Structure‐Based Analysis of ProteinPeptide Binding Affinities
Authors: Han Ke‐qiang , Wu Gang , Lv Fenglin 
Published: September 2013

AbstractProteinpeptide interactions have recently been found to play an essential role in constructing intracellular signaling networks. Understanding the molecular mechanism of such interactions and identification of the interacting partners would be of great value for developing peptide therapeutics against many severe diseases such as cancer. In this study, we describe a structure‐based, general‐purpose strategy for fast and reliably predicting proteinpeptide binding affinities. This strategy combines unsupervised knowledge‐based statistical potential derived from 505 interfacially diverse, non‐redundant proteinpeptide complex structures and supervised quantitative structure‐activity relationship (QSAR) modeling trained by 250 proteinpeptide interactions with known structure and affinity data. The built partial least squares (PLS) model is confirmed to have high stability and predictive power by using internal 5‐fold cross‐validation and rigorous Monte Carlo cross‐validation (MCCV). The model is further employed to analyze two large groups of HLA‐ and SH3‐binding peptides based upon computationally modeled structures. Satisfactorily, although the PLS model is originally trained with dissociation constants (Kd) of proteinpeptide binding, it shows a good correlation with other two affinity qualities, i.e. SPOT signal intensities (BLU) and half maximal competitive concentrations (IC50). Furthermore, we perform systematic comparisons of our method with several widely used, representative affinity predictors, including molecular mechanics‐based MM‐PB/SA, knowledge‐based DFIRE and docking score HADDOCK, on a small panel of elaborately selected proteinpeptide systems. It is demonstrated that (i) the QSAR‐improved statistical potential exhibits a comparable predictive performance with but can work faster than these traditional methods, and (ii) the crystal structure‐derived statistical potential also supports the modeled and solution structures of proteinpeptide complexes. We expect that this hybrid method can be exploited as a new scoring tool to facilitate, for example, peptide docking and virtual screening.
Existence and exponential convergence of almost periodic positive solution for Nicholson's blowflies discrete model with linear harvesting term
Authors: Yao Zhijian 
Published: September 2013

AbstractThis paper deals with a discrete Nicholson's blowflies model with linear harvesting term. By using contraction mapping fixed point theorem, we obtain sufficient conditions for the existence of unique almost periodic positive solution. Moreover, we investigate exponential convergence of the almost periodic positive solution by Lyapunov functional. Copyright © 2013 John Wiley & Sons, Ltd.
Prüfmittelüberwachung im Labor: Volumenmessgeräte
Authors: Schurz Christian 
Published: September 2013

AbstractAnalysen von chemischen oder pharmazeutischen Produkten sind nur dann verlässlich, wenn die Genauigkeit der Prüf‐ und Messmittel bekannt ist. Volumenmessgeräte sind ein Teil dieser Prüfmittel. Daher ist es für alle Labore sinnvoll und notwendig, Voll‐ und Messpipetten, Messkolben, Mess‐ und Mischzylinder sowie Büretten regelmäßig zu überwachen.
STRENGTHENING THE REGRESSION DISCONTINUITY DESIGN USING ADDITIONAL DESIGN ELEMENTS: A WITHIN‐STUDY COMPARISON
Authors: Wing Coady , Cook Thomas D. 
Published: September 2013

AbstractThe sharp regression discontinuity design (RDD) has three key weaknesses compared to the randomized clinical trial (RCT). It has lower statistical power, it is more dependent on statistical modeling assumptions, and its treatment effect estimates are limited to the narrow subpopulation of cases immediately around the cutoff, which is rarely of direct scientific or policy interest. This paper examines how adding an untreated comparison to the basic RDD structure can mitigate these three problems. In the example we present, pretest observations on the posttest outcome measure are used to form a comparison RDD function. To assess its performance as a supplement to the basic RDD, we designed a within‐study comparison that compares causal estimates and their standard errors for (1) the basic posttest‐only RDD, (2) a pretest‐supplemented RDD, and (3) an RCT chosen to serve as the causal benchmark. The two RDD designs are constructed from the RCT, and all analyses are replicated with three different assignment cutoffs in three American states. The results show that adding the pretest makes functional form assumptions more transparent. It also produces causal estimates that are more precise than in the posttest‐only RDD, but that are nonetheless larger than in the RCT. Neither RDD version shows much bias at the cutoff, and the pretest‐supplemented RDD produces causal effects in the region beyond the cutoff that are very similar to the RCT estimates for that same region. Thus, the pretest‐supplemented RDD improves on the standard RDD in multiple ways that bring causal estimates and their standard errors closer to those of an RCT, not just at the cutoff, but also away from it.