bluuebunny/crossref_metadata_2025_split huggingface dataset:
Chemical Composition and Biological Activity of Propolis from Brazilian Meliponinae
Authors: Velikova Milena , Bankova Vassya , Marcucci Maria C. , Tsvetkova Iva , Kujumgiev Atanas 
Published: February 2015

Abstract
Twenty-one propolis samples produced by 12 different Meliponinae species were analyzed by GC-MS. Several chemical types of stingless bees’ propolis could be grouped, according to the prevailing type of compounds like: “gallic acid”, “diterpenic” and “triterpenic” types. The results confirm that neither the bee species nor the geographical location determine the chemical composition of Meliponinae propolis and the choice of its plant source, respectively. This could be explained by the fact that Meliponinae forage over short distances (maximum 500 m) and thus use as propolis source the first plant exudate they encounter during their flights. The antibacterial, antifungal and cytotoxic activities of the samples were also investigated. Most samples had weak or no activity against E. coli, weak action against Candida albicans. Some of them showed significant activity against St. aureus., presumably connected to the high concentration of diterpenic acids. Samples rich in diterpenic acids possessed also high cytotoxic activity (Artemia salina test).
The Complex Structure of Ferri-ferribactins
Authors: Taraz Kambiz , Seipold Lars , Budzikiewicz Herbert 
Published: February 2015

Abstract
By comparison of the NMR data of the ferribactins from Pseudomonas chlororaphis ATCC 9446 and of P. fluorescens 18.1 with those of their Ga3+-complexes as models for the Fe3+-complexes it will be shown that only two bidentate ligands are provided for complexation, both located in the peptide chain. The two remainig free sites of the octahedral metal ion are probably occupied by solvent molecules.
Are Hydrophobins and/or Non-Specific Lipid Transfer Proteins Responsible for Gushing in Beer? New Hypotheses on the Chemical Nature of Gushing Inducing Factors
Authors: Hippeli Susanne , Elstner Erich F. 
Published: February 2015

Gushing of beer is characterised by the fact that immediately after opening a bottle a great number of fine bubbles are created throughout the volume of beer and ascend quickly under foam formation, which flows out of the bottle. This infuriating gushing phenomenon has been, and still is, a problem of world-wide importance to the brewing industry.
It is generally assumed that the causes of malt-derived gushing are due to the use of “weathered” barley or wheat and the growth of moulds in the field, during storage and malting. We now develop a hypothesis connecting several lines of evidence from different laboratories. These results indicate that the fungal hydrophobins, hydrophobic components of conidiospores or aerial mycelia, are gushing-inducing factors. Furthermore, increased formation of ns-LTPs (non-specific lipid transfer proteins), synthesised in grains as response to fungal infection, and their modification during the brewing process may be responsible for malt-derived gushing.
Pharmaco-Toxicological Study of Kageneckia oblonga, Rosaceae
Authors: Delporte Carla , Muñozb Orlando , Rojas Javier , Ferrándiz Marisa , Payá Miguel , Erazo Silvia , Negrete Rosa , Maldonado Sergio , San Feliciano Arturo , Backhouse Nadine 
Published: February 2015

The probable antipyretic, antiinflammatory, analgesic and antioxidant properties of Kageneckia oblonga, Rosaceae, were investigated and the major compounds of its active extracts were isolated. The study comprised the acute toxicity of the extracts of global methanol, hexane, dichloromethane and methanol. The cytotoxicity of global methanol extract was studied in three tumoral cell lines. All the extracts exhibited the pharmacological activities under study. Methanol and dichloromethane were the most toxic extracts. From the global methanol extract, isolations were performed of prunasin, 23,24- dihydro-cucurbitacin F, and a new cucurbitacin, 3β-(β-d-glucosyloxy)-16α,23α-epoxycucurbita-5,24-diene-11-one. The cytotoxicity of both cucurbitacins on human neutrophils at the assayed concentrations was not statistically significant. In-vitro assays showed that both cucurbitacins can be partly responsible for the analgesic, antipyretic, and anti-inflammatory activities.
Evaluation was done of the cytotoxicity of global methanol extract, 23, 24-dihydrocucurbitacin F, aqueous extracts and prunasin against P-388 murine leukaemia, A-549 human lung carcinoma and HT-29 colon carcinoma. Since global methanol extract presented a strong cytotoxicity against P-388 murine leukaemia, A-549 human lung carcinoma, and HT-29 cell lines, it is highly probable that this extract contain one or more cytotoxic compounds that could be investigated for their potential use as an agent against cancer.
Effect of Cu/Zn-Superoxide Dismutase from the Fungal Strain Humicola lutea 103 on Antioxidant Defense of Graffi Tumor-Bearing Hamsters
Authors: Ivanova Emilia , Angelova Maria , Slokoska Ludmila , Pashova Svetlana , Toshkova Reneta , Dolashka-Angelova Pavlina , Dimitrova Petya , Voelter Wolfgang 
Published: February 2015

A novel Cu/Zn-containing superoxide dismutase (SOD) was isolated from the fungal strain Humicola lutea 103. Previously, a protective effect of this enzyme (HLSOD) against tumor growth and also superoxide production in Graffi tumor-bearing hamsters (TBH) were established.
The aim of the present study was to investigate the effect of HLSOD on the activity of endogenous SOD and catalase in the cells from TBH during tumor progression. Our results point out that transplantation of Graffi tumor causes a significant decrease in SOD activity in the cells from liver of the hosts (from 35 to 59% compared to the control). In the tumor cells relatively low levels of SOD (about 7 U mg protein-1) were found, and Cu/ZnSOD was the main isoenzyme in total SOD activity. Tumor growth resulted in a reduction of catalase activity, which correlated with the process of tumor progression. A single dose (65 U) treatment with HLSOD caused an increase in endogenous SOD and catalase activity in healthy animals and resulted in restoration of the antioxidant ability in liver cells of the hosts at the early stage of tumor progression. The results show the possible participation of HLSOD in the host oxidant-antioxidant balance, which is probably one of the factors of its immunoprotective action established earlier.
Degradation of Aqueous 4-Chloroaniline by Ozonolysis and Combined γ-Rays-Ozone Processing
Authors: Sánchez Mónica , Getoff Nikola , Sümegi Laszlo , Zona Robert 
Published: February 2015

The decomposition of 4-chloroaniline (4-ClA), used as a model for water pollutants, was studied by ozonolysis as well as by γ-rays in the presence of ozone under comparable conditions. The degradation process was followed by absorption spectroscopy and by HPLC-method as well. Depending on the ozone concentration (mg O3/min) introduced into the aqueous solution the substrate is decomposed to a mixture of carboxylic acids, which can be entirely degradated by prolonged treatment.
The combined processing of 4-ClA by γ-irradiation in the presence of ozone proved to lead even to more efficient degradation of the substrate. Some primary reaction steps are briefly discussed.
Antigen Levels Of Urokinase Type Plasminogen Activator And Its Inhibitors In Primary Breast Cancer
Authors: Sałuda-Gorgul Anna , Pytel Jacek , Olborski Bogusław , Greger Janusz 
Published: February 2015

The aim of the study was to monitor urokinase plasminogen activator antigen concentrations and its type 1 (PAI-1) and type 2 (PAI-2) inhibitors in histologically defined forms of primary breast cancer and a comparison with these antigens levels in normal tissue. Another goal was a search for a relationship /or its lack/ between the occurrence of the new generation markers of neoplastic disease and a presence /or absence/ of lymph node metastases. UPA, PAI-1 and PAI-2 antigen levels were determined by ELISA tests in protein extracts of breast cancer tissues. Among the studied breast tumors 32 specimens were ductal carcinomas, 15 specimens were lobular carcinomas and the remaining 13 were other rare histological forms. In comparison to the obtained values of u-PA antigen levels in normal tissue, the values in neoplastic tissues were elevated several times: 11-fold, 6-fold and 15-fold in ductal c., lobular c. and other rare neoplasms. The values of PAI-1 antigen levels were about 20- fold higher for all studied, histologically defined primary breast cancers. The greatest differences of PAI-2 antigen levels growth was observed in histologically defined primary breast cancer forms. It was augmented 10-fold, 40-fold and 20-fold, respectively, for ductal carcinoma, lobular carcinoma and rare forms of neoplasms. In various forms of invasive breast cancer and those without lymph node metastases the content of u-PA, PAI-1 and PAI-2 were also significantly elevated. Among the new generation of independent markers of the neoplastic process, PAI-2 seems to be the most reliable marker for the identification of primary breast cancer.
The goal of the present study was to evaluate a possible combined prognostic value of the three major components of the u-PA system (u-PA, PAI-1 and PAI-2) in patients with defined histopathological forms of primary breast cancer
A Modified Procedure for Isolation of Yeast Mitochondrial DNA
Authors: Nedeva Trayana , Petrova Ventzislava , Hristozova Tsonka , Kujumdzieva Anna 
Published: February 2015

A modified, rapid and inexpensive method for preparation of mitochondrial DNA (mtDNA), suitable for molecular analysis is proposed. It comprises batch cultivation of Saccharomyces cerevisiae strain NBIMCC 583 on a simple nutrient medium at 28 °C; permeabialization of cells from late exponential growth phase with cetyltrimethylamonnium bromide, mechanical disintegration of the cell wall; preparation of a mitochondrial fraction and subsequent isolation and purification of mtDNA. The amount and the purity of the obtained mtDNA have been checked and its application for molecular analysis proven.
The main advantages of the proposed procedure for isolation of mtDNA are introduction of simple nutrient medium, replacement of the enzymatic lysis of the cell wall by the cheaper mechanical one, avoidance of ultracentrifugation steps and use of harmful chemical substances.
Exploration of Ternary Subsystems of Superalloys by High-Throughput Thin Film Experimentation: Optical and Electrical Data of the Co-Al-W System
Authors: Naujoks Dennis , Koenig Dennis , Ludwig Alfred 
Published: February 2015

AbstractThe complete ternary system Co-Al-W was fabricated as a thin film materials library by combinatorial magnetron sputtering. The materials library was investigated using high-throughput characterization methods such as optical measurements as well as automated resistance screening. The obtained data indicate possible phase regions and compositional regions which show early surface oxidation. The demonstrated approach illustrates that using high-throughput measurement methods provides a fast access to data of relatively unexplored materials systems. The gained data provides a valuable basis for further in-depth studies of the investigated materials systems.
Evaluation of Dislocation Mobility in Wurtzite Semiconductors
Authors: Yonenaga Ichiro 
Published: February 2015

ABSTRACTThe indentation hardness and yield strength of various wurtzite-structured semiconductors, such as AlN, GaN, InN, and ZnO, were summarized together with those of 6H-SiC. From analysis of the data, the activation energy for motion of an individual dislocation was deduced to be 2–2.7 and 0.7–1.2 eV in GaN and ZnO, respectively, and the evaluated activation energy for dislocation motion showed a dependence on the dislocation energy in the minimum length. The results were evaluated in terms of homology and the basic mechanism of the dislocation process. Dislocation motion is thought to be primarily controlled by the atomic bonding character of the semiconductors.
PLANO DE GERENCIAMENTO DE RESÍDUOS DA CONSTRUÇÃO CIVIL: UMA BREVE ABORDAGEM
Authors: Aires de Alencar Ari , Mayumi Murashita Takenaka Edilene 
Published: February 2015

Os geradores de resíduos da construção civil são responsáveis pela observância dos padrões previstos nas legislações específicas, referentes à disposição final, fazendo sua gestão interna e externa. O compromisso ambiental e a viabilidade econômica devem garantir a sustentabilidade, a condição e a solução para a destinação final dos resíduos, sendo competência da administração municipal adequar os locais para o recebimento de tais resíduos. O objetivo do presente artigo é fomentar novos debates sobre o tema a partir de uma breve abordagem sobre o Plano de Gerenciamento de Resíduos da Construção Civil, e para tal finalidade, a metodologia utilizada foi o levantamento de dados obtidos por meio de pesquisa bibliográfica. Palavras-chave: Resíduos da construção civil. Gestão de resíduos. Meio ambiente. PLAN OF CIVIL CONSTRUCTION RESIDUES MANAGEMENT: A BRIEF APPROACH ABSTRACT The generator of residue from civil construction are responsable for observing the patterns provided on the specified legislation, regarding the final dispose, making its internal and external management. The ambiental compromise and the economical feasibility must guarantee the sustainability, the conditions and solutions for the final destination of residues, it's municipal management competency to adapt the places to receive such residue. The objective of this article is create new discussions around the subject from a brief approach about the Plan of Residue Management from Civil Construction, and for this goal, the methodology used was the collect of data obtained by bibliographic research. Key-words: Residue of civil construction. Residue management. Environment. PLAN DE GESTIÓN DE RESIDUOS DE LA CONSTRUCCIÓN: UNA BREVE APROXIMACIÓN RESUMEN Los generadores de residuos de la construcción son responsables del cumplimiento de las normas especificadas en el específico, relacionado con las leyes de eliminación, por lo que su gestión interna y externa. El compromiso ambiental y viabilidad económica deberían garantizar la sostenibilidad, la condición y la solución para la eliminación de residuos, y la competencia de la medida la administración municipal los sitios para recibir este tipo de residuos. El propósito de este artículo es animar a continuar el debate sobre el tema desde una breve aproximación al Plan de Gestión de Residuos de la Construcción, y para este propósito, la metodología utilizada fue los datos de la encuesta obtenidos por medio de la literatura. Palabras clave: residuos de la construcción. Gestión de residuos. Medio Ambiente.
TRATAMENTO DE RESÍDUOS SÓLIDOS TECNOLÓGICOS: QUAL O DESTINO DO LIXO ELETRÔNICO DE EMPRESAS DE INFORMÁTICA NO MUNICÍPIO DE SERRA TALHADA-PE?
Authors: Luiz Lima de Paulo Felipe , Íris Maciano de Andrada Zara 
Published: February 2015

Muitas são as consequências que o meio ambiente sofre por causa da poluição. Esse problema a muito vem sendo discutido e sabe-se atualmente que o homem tem responsabilidades ambientais e sociais. Nesta perspectiva, essa pesquisa tem como foco saber como tem sido feito o descarte do lixo eletrônico e qual tem sido o destino dos equipamentos das lojas de informática da cidade de Serra Talhada-PE. Objetivou-se também saber se essas empresas conhecem e praticam a logística reversa. Como metodologia, aplicou-se questionário semiaberto para avaliar o nível de gestão ambiental das empresas pesquisadas. Ao final, percebeu-se que as empresas ainda não estão totalmente adequadas ao que se espera para boas práticas de gestão ambiental. PALAVRAS-CHAVE: Impactos ambientais, lixo eletrônico, Serra Talhada - PE. SOLID WASTE TREATMENT TECHNOLOGY: WHAT IS THE FATE OF ELECTRONIC WASTE TECHNOLOGY COMPANIES IN THE CITY OF SERRA TALHADA - PE? ABSTRACT There are many consequences that the environment suffers because of pollution. This problem has been discussed a lot and is now known that man has environmental and social responsibilities. In this perspective, this research focuses on knowledge as has been done to discard the junk mail and what has been the destination of equipment computer stores in the city of Serra Talhada-PE. Also aimed to find out if these companies know and practice reverse logistics. The methodology was applied semi-open questionnaire to assess the level of environmental management of the companies surveyed. At the end, it was noticed that companies are not fully appropriate to what is expected for good environmental management practices. KEY-WORDS: Environmental impacts, technological waste, Serra Talhada – PE. RESIDUOS SÓLIDOS TRATAMIENTO DE TECNOLOGÍA: ¿CUÁL ES EL DESTINO DE ELECTRÓNICOS EMPRESAS TECNOLÓGICAS DE RESIDUOS EN LA CIUDAD DE SERRA TALHADA - PE? RESUMEN Hay muchas consecuencias que sufre el medio ambiente debido a la contaminación. Este problema se ha discutido mucho y ahora se sabe que el hombre tiene responsabilidades ambientales y sociales. En esta perspectiva, esta investigación se centra en el conocimiento como se ha hecho para descartar el correo basura y lo que ha sido el destino de los equipos de las tiendas de computadoras en la ciudad de Serra Talhada-PE. También tuvo como objetivo determinar si estas empresas saben y logística inversa práctica. La metodología se aplicó cuestionario semi-abierto para evaluar el nivel de la gestión ambiental de las empresas encuestadas. Al final, se dio cuenta de que las empresas no son totalmente adecuadas para lo que se espera para las buenas prácticas de gestión ambiental. PALABRAS-CLAVE Los impactos ambientales, residuos tecnológicos, Serra Talhada – PE.
ANÁLISE DE RUÍDOS EM METRÓPOLES BRASILEIRAS: OBSERVAÇÕES EM CAMPO NA ZONA NORTE CARIOCA
Authors: Borges Mamede Bruno , Devides Moreno Lucas , Augusto Noronha de Castro Pinto Fernando 
Published: February 2015

Este estudo possui como objetivo a observação do comportamento dos níveis de pressão sonora em uma determinada área da Zona Norte da cidade do Rio de Janeiro, a partir dos conceitos de Engenharia Acústica. No caso de extrapolação dos limites legais estabelecidos quais medidas podem ser adotadas para mitigar o problema, tal qual uma reflexão a cerca de normatização destes. Entretanto, além da apresentação e discussão dos resultados bem como possíveis medidas mitigadoras, o principal objetivo aqui está no impacto dos níveis de ruído no cotidiano urbano a partir de sua disseminação (mensurável) no espaço das cidades e as possíveis formas de compatibilização destes para implemento da qualidade de vida local. Palavras-Chave: Engenharia Acústica, Engenharia Urbana, Geografia Urbana, Geografia dos Transportes. ANALYSIS NOISE IN BRAZILIAN METROPOLISES: NOTES ON FIELD IN NORTH ZONE CARIOCA ABSTRACT This study’s objective is to observe the conduct of sound pressure levels in a determinate area of Rio de Janeiro’s North Zone, based in the Acoustics Engineering’s concepts. In the case of legal limits’ extrapolation which measures could be adopted to mitigate the problem, such as a reflection about the normalization of those ones. However, beyond presentation, discussion of the results and mitigate measures, the main goal here is in the impact of noise levels in the urban daily activities and the possible forms of compatibility for local life quality implement. Keywords: Acoustics Engineering, Urban Engineering, Urban Geography, Transportation Geography. RUIDO EN ANÁLISIS METRÓPOLIS BRASILEÑAS: NOTAS EN CAMPO EN ZONA NORTE CARIOCA RESUMÉN El objetivo de esta investigación es la observación del comportamiento de los niveles de presión sonora en un área determinada de la Zona Norte de la ciudad del Río de Janeiro, de acuerdo con los conceptos de Ingeniería Acústica. En el tocante a la extrapolación de los límites legales cuales medidas se pueden ser hechas para la mitigación de la problemática, así como una reflexión acerca de los propios parámetros de normalización de esas. Para tanto, además de la presentación, discusión de los resultados y maneras de mitigar los problemas, la meta principal de este estudio está en el impacto que los niveles de sonido afectan las actividades urbanas diarias frente las posibles formas de compatibilización para implemento a la calidad de vida local. Palabras-Clave: Ingeniera Acústica, Ingeniería Urbana, Geografía Urbana, Geografía de Transportes.
ANÁLISE ECONÔMICA DE OFERTA E DEMANDA DO ABACATE NA ALTA PAULISTA
Authors: Ferrari Putti Fernando , César Góes Bruno , Fernando Cataneo Pedro 
Published: February 2015

O objetivo deste trabalho, visa analisar a oferta e demanda de abacate no Brasil, identificando os estados produtores e onde está concentrada a sua produção; a demanda brasileira de consumo do fruto em relação ao mundo, informando os benefícios nutricionais do abacate, no combate e prevenção doenças cardiovasculares, entre outras; e tendo como foco de estudo, a produção na região da alta paulista. Foram feitos levantamento de dados através de pesquisas com base no Escritório de Desenvolvimento Regional de Tupã (EDR) e do Instituto de Economia Agrícola (IEA). PALAVRAS-CHAVE: Exportação, consumo, mercado. ECONOMIC ANALYSIS OF SUPPL AND DEMAND OF AVOCADO PAULO ON HIGH ABSTRACT This study aims to analyze the supply of avocado in Brazil, identifying the producing states and where their production is concentrated; Brazilian demand consumption of the fruit in relation to the world, stating the nutritional benefits of avocados, in combating and preventing cardiovascular diseases, among others; and focusing the study on the production of high Paulista region. Survey data were made through research based in the Office of Regional Development Tupa (EDR) and the Institute of Agricultural Economics (IEA). KEY-WORDS: Export.Consumption. Market. ANÁLISIS E ECONÔMICO DE LA OFERTA Y LA DEMANDA DE AGUACATE PAULO EM ALTA RESUMEN Este estudio tiene como objetivo analizar la oferta de palta en Brasil, la identificación de los estados productores y en los que su producción se concentra; el consumo de la demanda brasileña de la fruta en relación con el mundo, exponiendo los beneficios nutricionales de los aguacates, en la lucha y prevención de las enfermedades cardiovasculares, entre otras; y se centra el estudio en la producción de alta región Paulista. Los datos de encuestas se realizaron a través de la investigación basada en la Oficina de Desarrollo Tupa Regional (EDR) y el Instituto de Economía Agrícola (IEA). PALABRAS-CLAVE Exportación. El consumo. El mercado.