bluuebunny/crossref_metadata_2025_split huggingface dataset:
A heuristic with a performance guarantee for the commodity constrained split delivery vehicle routing problem
Authors: Petris Matteo , Archetti Claudia , Cattaruzza Diego , Ogier Maxime , Semet Frédéric 
Published: July 2024

AbstractThe commodity constrained split delivery vehicle routing problem (C‐SDVRP) is a routing problem where customer demands are composed of multiple commodities. A fleet of capacitated vehicles must serve customer demands in a way that minimizes the total routing costs. Vehicles can transport any set of commodities and customers are allowed to be visited multiple times. However, the demand for a single commodity must be delivered by one vehicle only. In this work, we developed a heuristic with a performance guarantee to solve the C‐SDVRP. The proposed heuristic is based on a set covering formulation, where the exponentially‐many variables correspond to routes. First, a subset of the variables is obtained by solving the linear relaxation of the formulation by means of a column generation approach which embeds a new pricing heuristic aimed to reduce the computational time. Solving the linear relaxation gives a valid lower bound used as a performance guarantee for the heuristic. Then, we devise a restricted master heuristic to provide good upper bounds: the formulation is restricted to the subset of variables found so far and solved as an integer program with a commercial solver. A local search based on a mathematical programming operator is applied to improve the solution. We test the heuristic algorithm on benchmark instances from the literature. The comparison with the state‐of‐the‐art heuristics for solving the C‐SDVRP shows that our approach significantly improves the solution time, while keeping a comparable solution quality and improving some best‐known solutions. In addition, our approach is able to solve large instances with 100 customers and six commodities, and also provides very good quality lower bounds. Furthermore, an instance of the C‐SDVRP can be transformed into a CVRP instance by simply duplicating each customer as many times as the requested commodities and by assigning as demand the demand of the single commodity. Hence, we compare heuristics for the C‐SDVRP against the state‐of‐the‐art heuristic for the Capacitated Vehicle Routing Problem (CVRP). The latter approach revealed to have the best performance. However, our approach provides solutions of comparable quality and has the interest of providing a performance guarantee.
Rotational Spectroscopy as a Tool to Characterize Sweet Taste: The Study of Dulcin
Authors: Juarez Gabriela , Alonso Elena R. , Aguado Raúl , León Iker 
Published: July 2024

AbstractAccording to old theories of sweetness, the perception of sweet substances is closely linked to the arrangement of atoms within them. To assess the validity of these theories, we conducted an analysis of the structure of the artificial sweetener dulcin for the first time, utilizing microwave spectroscopy and a laser ablation source. These techniques have enabled the identification of two conformers, which are stabilized by an intramolecular hydrogen bond between the amino group and the phenyl ring. The observed conformations were examined in light of the Shallenberger‐Acree‐Kier molecular theory of sweet taste, and they align with the hypothesized criteria. Furthermore, the study illustrates how conformational relaxation can alter the equilibrium conformational distribution, resulting in the absence of certain conformers in the conformational landscape.
Transition Metal‐Driven Selectivity in Direct C−H Arylation of Imidazo[2,1‐b]Thiazole
Authors: Del Vecchio Antonio , Rosadoni Elisabetta , Ballerini Lorenzo , Cuzzola Angela , Lipparini Filippo , Ronchi Paolo , Guariento Sara , Biagetti Matteo , Lessi Marco , Bellina Fabio 
Published: July 2024

AbstractA selective direct arylation of the different Csp2‐H bonds of imidazo[2,1‐b]thiazole with (hetero) aryl halides can be achieved simply by switching from a palladium catalyst system to the use of stoichiometric amounts of copper. The observed selectivity, also rationalized by DFT calculations, can be explained by a change in the mechanistic pathways between electrophilic palladation and base‐promoted C−H metalation.
Food Protein‐Derived Zinc‐Binding Peptides: Isolation, Purification, and Biological Aspects
Authors: Mukhamedov Nurkhodja , Asrorov Akmal M. , Kayumov Muzaffar , Wali Ahmidin , Aisa Haji Akber , Mirzaakhmedov Sharafitdin , Yili Abulimiti 
Published: July 2024

ABSTRACTZinc is the second most valuable microelement after iron, according to its abundance in the human body. Supplementation of this metal is not straightforward because of several factors like phytates and interference of other minerals during gastrointestinal digestion. For the last several years, intensive research has been developing new forms of zinc supplements based on zinc‐binding peptides from food products. Except for the advantages of supplementation, zinc‐peptide complexes are expected to be drug candidates against various diseases. Zinc supplementation can be improved by protein hydrolysates and peptides due to their zinc‐binding ability. They enhance zinc supplementation and contribute to preventing conditions leading to zinc deficiency that cause various diseases. Research on food‐derived zinc‐binding peptides is progressing in two directions: the isolation and identification of individual peptides (1) and the preparation of zinc complexes of protein hydrolysates (2). Both approaches are primarily aimed at developing effective mineral supplements, although some work on the second approach is also related to nutrition and therapy. Because zinc–protein hydrolysate complexes are nonstandardized mixtures of peptides, their biological activity mechanisms can be difficult to study. Therefore, it is important to focus more research on the biological activity of individual zinc‐binding complexes and their zinc complexes. This work reviewed recent advances in isolating and identifying zinc‐binding peptides from food sources, preparing protein hydrolysate–zinc complexes, and their biological activities. The established sequences of zinc‐binding peptides have been compiled into a table to review their amino‐acid composition and sequence. We also highlighted approaches for isolating and determining the zinc‐binding capacity of peptides in this class. The structural features of peptides affecting their zinc‐binding property were discussed in one section.
Cover Image, Volume 124, Issue 12
Authors: Salehfar S. , Azami S. M. 
Published: July 2024

The cover image is based on the Research Article Asymmetric electronic deformation in graphene molecular capacitors by S. Salehfar et al., https://doi.org/10.1002/qua.27426.[Correction added on 25 July 2024, after first online publication: Cover has been replaced.]
image
Economic and health‐related quality of life impacts of receiving recurrent miscarriage care in Ireland: Exploratory analysis drawing on results from a national care experience survey
Authors: Flannery Caragh , Burke Lee‐Ann , Gillespie Paddy , Hennessy Marita , O'Leary Hannah , Dennehy Rebecca , O'Donoghue Keelin 
Published: July 2024

AbstractObjectiveUndergoing miscarriage is a significant life event and having recurrent miscarriage (RM) can magnify psychological effects, including anxiety and depression, following a miscarriage. There is limited published evidence on impacts of RM on employment, personal finances, quality of life and use of health care services.This study examines the impact on quality of life, work experiences and personal finances of people receiving RM care.MethodsWe conducted a cross‐sectional study using an anonymous national survey of people who experienced ≥2 consecutive first‐trimester miscarriages and received care for RM in Ireland in a 10‐year period. Questions encompassed sociodemographic information, details of RM care and workplace presenteeism (SPS‐6), health‐related quality of life (HRQOL) (SF‐12), healthcare utilisation and out‐of‐pocket expenses.ResultsOf the 135 participants included in analysis, 79% were aged 33–44 years. Participants scored low on the SF‐12 mental component (38.7), with 50% well below population norm. Participants needed time off work for investigations (66%), receiving results (62%), early reassurance scans (77%) and attending support services (18%). Participants spent, on average, 82 h off work attending RM care appointments. 70% experienced decreased productivity at work. Participants travelled 36.54 km, on average, attending RM care appointments, costing on average €372/participant for transport, parking and fuel. Other out‐of‐pocket expenses included further investigations, scans and services: total cost averaged €7930 per participant, plus costs for care of children/dependents while attending appointments of €245/participant.ConclusionImplementing care standards, clinical guidelines and interventions supporting women/couples with RM, with appropriate funding, is needed to mitigate psycho‐social impacts and prevent high patient costs.
Flood Potential Portal: A web tool for understanding flood variability and predicting peak discharges
Authors: Yochum Steven E. , Wible Tyler , Korsa Matthew , Ghanbari Mahshid , Arabi Mazdak 
Published: July 2024

AbstractThe Flood Potential Portal (https://floodpotential.erams.com/) has been developed for the contiguous United States, as a practitioner‐focused tool that uses observational data (streamgages) to enhance understanding of how floods vary in space and time, and assist users in making more informed peak discharge predictions for infrastructure design and floodplain management. This capability is presented through several modules. The Mapping module provides tools to explore variability using multiple indices, and provides detailed information, figures, and algorithms describing and comparing flooding characteristics. The Cross‐Section Analysis module allows users to cut regional‐scale sections to interpret the role of topography in driving flood variability. The Watershed Analysis module provides multiple methods for quantifying expected peak discharge magnitudes and flood frequency relationships at user‐selected locations, including the integration of observed trends in flood magnitudes due to climate change and other sources of nonstationarity into decision making. The Streamgage Analysis module performs streamgage flood‐frequency analyses. These modules are based in part on the flood potential method, through the use of 207 zones of similar flood response defined using more than 8200 streamgages with watershed areas <10,000 km2. Regression models that define each zone had high explained variance (average R2 = 0.93). An example is provided to illustrate use of the Flood Potential Portal for the design of a hypothetical bridge replacement.
More is (sometimes) merrier: Heterogeneity in demand spillovers and competition on a digital platform
Authors: Raj Manav 
Published: July 2024

AbstractResearch SummaryPlatforms create value by connecting users to complementors offering goods or services. Complementors compete on platforms but may also benefit each other by drawing demand to the platform, which may then “spillover” from one complementor to another. This tension raises the question: When are relationships between complementors competitive versus complementary? To help address this question, I apply theory on agglomeration‐driven demand spillovers to examine when on‐platform demand spillovers created by peer product launch are larger versus smaller. Studying the Spotify platform, I find spillovers are larger, and peer album release more beneficial to an artist, when the peer stimulates greater demand expansion, platform‐mediated inter‐complementor proximity is higher, and the artist benefits more from consumer learning. Findings extend literature on on‐platform competition and inform complementor strategy.Managerial SummaryOn digital platforms, complementor product launch may hurt peer performance by causing substitution or may benefit peer performance by drawing demand to the platform which may then “spillover” from the complementor to a peer. Studying the Spotify platform, I examine when such spillovers are larger versus smaller, shedding light on when peer product launch is beneficial versus detrimental for complementors competing on digital platforms. On Spotify, demand spillovers are larger, and peer album release more beneficial to an artist, when peer album release draws listeners to the platform, Spotify recommendations connect the artist to the peer, and the artist reaches new or unfamiliar listeners. The findings suggest that, on platforms featuring demand spillovers, complementors can take strategic actions to leverage spillovers and improve performance.
Aramid‐Reinforced UV Curable Adhesive Resins for Use As an Interlayer in Laminated Glass
Authors: Lee Jineun , Lee Hanna , Kwak Giseop 
Published: July 2024

AbstractColorless, transparent, and mechanically robust aramid polymers are synthesized from two diamine monomers with strong electron‐withdrawing groups, using low‐temperature solution condensation with diacid chloride. The aramids dissolved very well in the liquid acrylamide monomers. When N,N‐dimethylacrylamide (DMA) is used as a reactive diluent, films with the desired features are produced from the hybrid aramid‐DMA resins via ultraviolet (UV) curing. The hybrid films are colorless and transparent in the visible region and showed an increase in the glass transition temperature, tensile strength, and elastic modulus in proportion to the aramid content. Laminated glass is manufactured using the hybrid resin as an interlayer, which exhibits very strong adhesion between the two sheets of glass, is not easily broken by an external impact, and do not scatter fragments. Moreover, the laminated glass do not distort images and functioned very effectively in UV blocking, soundproofing, and suppressing changes in the ambient temperature. Heat treatment further improves the light transmittance and impact resistance of the laminated glass. Laminated glass specimens with various fluorescence colors are also manufactured. Aramid‐reinforced films prepared using N,N‐diethylacrylamide as a reactive diluent underwent thermally induced phase separation in a wet state, providing smart glass with a privacy protection function.
Valorization of Agriculture Residues into Value‐Added Products: A Comprehensive Review of Recent Studies
Authors: Hoang Tuan‐Dung , Van Anh Nguyen , Yusuf Mohammad , Ali S. A Muhammed , Subramanian Yathavan , Hoang Nam Nguyen , Minh Ky Nguyen , Le Van‐Giang , Thi Thanh Huyen Nguyen , Abi Bianasari Alien , K Azad Abul 
Published: July 2024

AbstractGlobal agricultural by‐products usually go to waste, especially in developing countries where agricultural products are usually exported as raw products. Such waste streams, once converted to “value‐added” products could be an additional source of revenue while simultaneously having positive impacts on the socio‐economic well‐being of local people. We highlight the utilization of thermochemical techniques to activate and convert agricultural waste streams such as rice and straw husk, coconut fiber, coffee wastes, and okara power wastes commonly found in the world into porous activated carbons and biofuels. Such activated carbons are suitable for various applications in environmental remediation, climate mitigation, energy storage, and conversions such as batteries and supercapacitors, in improving crop productivity and producing useful biofuels.
Delayed healing is common in in‐situ urethroplasty patients after artificial sphincter cuff erosion
Authors: Matz Ethan L. , Glover Banahene K. , Krug Aaron M. , Langford Brian T. , Franzen Bryce P. , Hudak Steven , VanDyke Maia , Morey Allen F. 
Published: July 2024

AbstractIntroductionUrethral erosion is a known complication of artificial urinary sphincter (AUS) surgery. We performed an in‐situ urethroplasty (ISU) to reduce the healing time and time to reimplantation of the AUS. We sought to assess urethral integrity one month after ISU and to identify factors associated with delayed healing in our high‐volume tertiary referral center experience.MethodsA retrospective review of our AUS database from 2009 to 2023 was conducted to identify all ISU cases. Patients were stratified as healed or non‐healed based on the absence of extravasation on voiding cystourethrogram (VCUG) obtained 4 weeks postoperatively. Background characteristics were evaluated including age, body mass index, diabetes, hypogonadism and smoking history. Operative variables included degree of erosion, location of defect, and the number of stitches required for repair.ResultsAmong 98 patients undergoing an ISU, 61 underwent VCUG at one month. Of these, 34.4% (21/61) had evidence of delayed healing on VCUG requiring prolonged catheterization. Although a higher average number of repair sutures were used in ISU, this was not significant (p = 0.381). The most common complication in both groups was urinary tract infection (UTI). Non‐healed patients had a higher rate of UTI, without significant predilection towards fistula, stricture or diverticulum. No other patient or operative characteristic was significantly different between groups.ConclusionDespite an aggressive approach to management via ISU, many patients still require prolonged catheterization after AUS erosion to ensure complete healing of the defect.
The role of the forensic archeologist and anthropologist in recovery of human remains from fatal fires
Authors: Swales Diana , Hackman Lucina 
Published: July 2024

AbstractFatal fires pose complex challenges for responders due to the requirement to investigate all aspects of the fire using methods that maximize evidence recovery and integrity, including optimal and respectful recovery of the deceased. In this article, the authors consider the value of the inclusion of both forensic archeologists and forensic anthropologists in circumstances of fatal fire, identifying some of the challenges posed by these environments and what each can contribute.This article is categorized under:
Crime Scene Investigation > Crime Scene Examination
Forensic Anthropology > Forensic Archaeology
Forensic Anthropology > Taphonomic Changes and the Environment
Enduring inequalities: Revascularization before and after the ACA
Authors: Gusmano Michael K. , Weisz Daniel , Palghat Swati , Rodwin Victor G. 
Published: July 2024

AbstractThe use of revascularization (coronary artery bypass surgery [CABG] and percutaneous coronary intervention [PCI]) in the United States is declining, but they remain important procedures for the treatment of patients with coronary artery disease. There are large and long‐standing disparities in the use of revascularization among patients hospitalized with heart disease. In this article, we investigate whether the implementation of the Patient Protection and Affordable Care Act (ACA) is associated with a reduction in disparities in the use of revascularization. We use data from the Agency for Healthcare Research and Quality (AHRQ)'s National Inpatient Sample (NIP) of the Healthcare Cost and Utilization Project (HCUP) project to compare the use of revascularization among patients 45 years and older in the United States in 2012 and 2018. For both years, we conducted multiple logistic regression analysis to assess the factors associated with coronary revascularization among patients hospitalized with heart disease. Hospitalizations for heart disease and the use of revascularization both fell between 2012 and 2018 at a rate that was greater than the reduction in heart disease deaths in the country. These findings are consistent with the clinical literature on the growth of medical management of heart disease. Disparities in the use of revascularization, by gender, insurance status, neighborhood, and race/ethnicity, were just as large after the implementation of the ACA in 2014. The expansion of insurance by the ACA, alone, was insufficient to reduce disparities in the use of revascularization in patients with diagnosed coronary heart disease in the United States.
Structures of Large Tin(IV) Oxo Clusters
Authors: Schubert Ulrich 
Published: July 2024

AbstractThe article reviews and categorizes the structures of tin oxo clusters with nuclearities ≥6 and compares them with oxo clusters of the other group 4 and 14 metals. Basic construction principles of the cluster core are worked out by comparing the different cluster types and by identifying smaller building blocks. The comparison also shows how the different cluster types are influenced by the interplay between the ligands which stabilize the cluster core and the bridging oxygen atoms.
Nation Branding, Digital Advocacy and Feminist Foreign Policy
Authors: Aggestam Karin , Rosamond Annika Bergman , Hedling Elsa 
Published: July 2024

AbstractThis chapter examines how Sweden’s feminist foreign policy was constructed and managed as a nation brand during its eight years of existence. This particular nation brand built on and was informed by Sweden’s longstanding state feminist tradition as well as its more recent digital sophistication. As the chapter shows, Sweden’s feminist foreign policy was an exercise in feminist branding, paired with a strong awareness that digital communication of feminist values required both pragmatism and policy adaptation. We analyse how strategies of hashtag feminism triggered resonance among global audiences not least in digital advocacy networks, drawing attention to and mobilising support for the distinct values and ambitions of Sweden’s feminist foreign policy. Finally, we examine how Sweden’s feminist foreign policy was contested by actors globally. To illustrate this process of contestation, we pay particular attention to a Swedish state visit to Iran in 2017, which triggered a range of strong online reactions.
Railway Demand Evaluation: HSR Induced Component
Authors: Russo Francesco , Moschella Marialuisa , Musolino Giuseppe 
Published: July 2024

AbstractThe introduction of High-Speed Rail (HSR) systems in different countries of the world has demonstrated to be a decisive solution for the sustainable development of the mobility and economic growth, and for the promotion of social inclusion. This paper aims to identify the main methodological approaches to evaluate travel demand induced by the presence of HSR services through a systematic review of the relevant scientific literature. The objective is the exploration of the proposed models and methodological gaps present in the existing research. The findings of this study provide a solid basis for future development in the study of induced demand generated by HSR services, suggesting necessary directions for the advancement of demand analysis methodologies, thus contributing to a more comprehensive analysis of the effects of high-speed rail systems.
Dynamic Structure of Fares for High Speed Rail Services
Authors: Russo Francesco , Sgro Domenico , Musolino Giuseppe 
Published: July 2024

AbstractThe entering of High Speed Rail (HSR) passenger services caused competition in the market with other conventional rail services, and other transport modes. The dynamic structure of fares in the HSR services assume a crucial role in the supply of scheduled transport services and influence travelers’ choice behavior. The HSR fare structures, similarly to the air services, is characterized by evolutions and changes over time due to several factors, such as travelers’ behavior; strategies of the companies supplying the HSR services. The results reported in the paper contain a framework for analysis of the evolution of fares over time in relation to the day of ticket purchase and of the day of trip. A sample representation of a pilot case study implemented on the existing HSR line between Rome and Milan (Italy), where two HSR companies operate and compete each other, is presented.The aim of the study is to identify the characteristics fares evolution over time in the HSR market. This work is useful for support transport planners and decision-makers for the ex-ante evaluation of fare structure in terms of users’ behavior.