bluuebunny/crossref_metadata_2025_split huggingface dataset:
Systematic meta-analysis of individual selective serotonin reuptake inhibitor medications and congenital malformations
Authors: Myles Nicholas , Newall Hannah , Ward Harvey , Large Matthew 
Published: June 2013

Context: It has been suggested that the commonly prescribed class of antidepressants selective serotonin reuptake inhibitors (SSRIs) are associated with birth defects. However, the teratogenic effect of individual SSRIs has not been previously compared using meta-analysis. Objective: To determine the strength of the association between individual SSRIs and major, minor, and cardiac malformation among infants born to women taking these medications. Data sources: Electronic search of CINAHL, EMBASE, Medline, PsycINFO, and ISI Web of Science using the search terms (SSRI OR antidepressant) AND (obstetric outcome OR malformation OR birth outcome OR teratogen), supplemented by manual searching of published references and requests of primary researchers for unpublished data. Study selection: There were 115 studies identified by electronic search and reviewed in full text, which yielded 16 papers reporting 36 data samples for major malformations, nine papers reporting 26 data samples for cardiac malformations, and four papers reporting seven data samples for minor malformations. Data synthesis: Fluoxetine (OR 1.14, 95% CI 1.01–1.30) and paroxetine (OR 1.29, 95% CI 1.11–1.49) were associated with increased risk of major malformations. Paroxetine was associated with increased risk of cardiac malformations (OR 1.44, 95% CI 1.12–1.86). Sertraline and citalopram were not significantly associated with congenital malformation. Between-sample heterogeneity was low and a range of methodological considerations had no significant impact on effect size. There was little evidence of publication bias. Conclusions: Fluoxetine and paroxetine should be avoided in the first trimester and among those at risk of an unplanned pregnancy.
The Association Between Combination of Hand Force and Forearm Posture and Incidence of Lateral Epicondylitis in a Working Population
Authors: Fan Z. Joyce , Silverstein Barbara A. , Bao Stephen , Bonauto Dave K. , Howard Ninica L. , Smith Caroline K. 
Published: June 2013

Objective: The objective of this prospective study is to investigate the exposure–response relationships between various workplace physical exposures of force, repetition, and their combination assessed at an individual level with lateral epicondylitis (LE). Background: Workplace upper extremity musculoskeletal disorders (UEMSDs) are prevalent, disabling, and expensive. LE is one of the major UEMSDs in active workers. Method: We used detailed health history, symptoms, and physical examination for identifying incidence and detailed exposure assessment to capture work tasks of each worker and to measure quantitative mechanical workload. We used counting process style input of proportional hazards regression for modeling cumulative incidence that accounts for changed exposure estimates during the follow-up period when respondents change jobs. Results: The incidence rate of LE on the dominant side was 4.91 per 100 person-years. Adjusted for age and gender, the combined effect of forearm pronation ≥45° for ≥40% of time and time spent with forceful exertion, including any power grip (hazard ratio [HR] = 2.8, 95% confidence interval [CI] = [1.35–5.77]), lifting for ≥3% of time (HR = 2.50, 95% CI = [1.19–5.24]), and duty cycle for forceful exertion for ≥10% (HR = 2.25, 95% CI = [1.09–4.66]), were significant predictors of dominant side LE, whereas neither the awkward posture nor the forceful exertion alone was significant. Older workers with jobs requiring a high percentage of time working with force in combination with awkward postures of forearm were more likely to predict LE. Conclusion: This study shows the evidence of the etiologic role of strenuous manual tasks in the occurrence of LE.
Neoliberalism, Law, and Strikes
Authors: Atiles-Osoria José M. 
Published: June 2013

The exercise of power in the student strikes at the University of Puerto Rico in 2010–2011 was determined in part by Puerto Rico’s colonial condition, and at the same time the strikes influenced the ideological construction of the country’s colonial conflict. The law was used by both sides as a strategy for advancing their interests. At the same time, the criminalization and state terrorism employed in response to the strikes were the same strategies traditionally used against Puerto Rican independence movements, and the university administration and the government developed new ways of thwarting political demonstrations. The colonial conflicts and the student strikes fed each other and created a new pattern of political discussion and action. El ejercicio del poder en las huelgas de estudiantes en la Universidad de Puerto Rico durante 2010-2011 se determinó en parte a raíz de la condición colonial de Puerto Rico, a la vez que las huelgas mismas influenciaron la construcción ideológica del conflicto colonial del país. El derecho fue utilizado por el gobierno de Puerto Rico, por la administración universitaria y por los estudiantes como una estrategia para favorecer sus intereses. Al mismo tiempo, contra las huelgas fueron empleadas las mismas estrategias de criminalización y terrorismo de estado tradicionalmente utilizadas contra los movimientos independentistas. No obstante, la administración universitaria y el gobierno desarrollaron nuevas estrategias para frustrar las manifestaciones políticas. De esta forma, el conflicto colonial y las huelgas se influenciaron mutuamente y crearon un nuevo patrón de discusión y acción políticas.
Regina José Galindo’s Body Talk
Authors: Barbosa Emilia 
Published: June 2013

In the context of neoliberalism and the culture of violence in Guatemala, the performance art of Regina José Galindo uses a language of provocation that embodies political struggle. Galindo’s art does not realistically portray violence; rather, it opens venues for discussion on violence against women and possible solutions on both a regional and a global level. Performative violence shocks the spectator out of his/her normalized insensitivity to daily gender-based violence. The privileged physicality of the artist’s own body challenges the naturalization of violence against women in contemporary Guatemalan society. En el contexto del neoliberalismo y la cultura de violencia en Guatemala, el arte escénico de Regina José Galindo utiliza un lenguaje de provocación que encarna la lucha política. El arte de Galindo no representa la violencia de manera realista; más bien, abre espacios de discusión sobre la violencia contra mujeres y posibles soluciones a nivel tanto regional como mundial. La violencia en escenario sacude a los espectadores de su insensibilidad normalizada a la violencia diaria de género. En el caso de Galindo, la fisicalidad privilegiada de su propio cuerpo desafía la naturalización de la violencia contra las mujeres en la sociedad contemporánea guatemalteca.
Violence against Women and the Contradictions of Rights-in-Practice in Rural Ecuador
Authors: Friederic Karin 
Published: June 2013

Las Colinas, a rural region of northwestern Ecuador, is considered a lawless frontier. Violence against women is common, in part because of its perceived legitimacy. Since 2000, various nongovernmental organizations have conducted workshops on women’s rights, producing contradictory effects on social relations and rates of violence. Understandings and manifestations of gender violence are changing as transnational human rights discourses enter Las Colinas and local women and men learn about human rights and gain access to state-based justice. Human rights and improved access to justice offer powerful openings for women and families, but their empowering potential is limited by growing social and economic vulnerability and discrepancies between rights-based subjectivities and preexisting understandings of the self. Las Colinas, una región rural del noroeste de Ecuador, se considera una frontera sin ley. La violencia contra las mujeres es común, en parte debido a que se percibe como legítima. Desde el año 2000, diversas organizaciones no gubernamentales han llevado a cabo talleres sobre derechos de la mujer, generando efectos contradictorios en las relaciones sociales y los índices de violencia. Las concepciones y las manifestaciones de violencia de género están cambiando conforme discursos transnacionales de derechos humanos que llegan a Las Colinas y mujeres y hombres locales aprenden acerca de éstos y obtienen acceso a la justicia estatal. Los derechos humanos y un mayor acceso a la justicia abren nuevas puertas para las mujeres y las familias, pero su empoderamiento potencial está limitado por una creciente vulnerabilidad social y económica, así como las discrepancias entre subjetividades basadas en dichos derechos y nociones preexistentes del ser.
Comparison of the safety and efficacy of conventional monopolar and 2-micron laser transurethral resection in the management of multiple nonmuscle-invasive bladder cancer
Authors: Liu H , Wu J , Xue S , Zhang Q , Ruan Y , Sun X , Xia S 
Published: June 2013

Objectives To compare the safety and efficacy of conventional monopolar transurethral resection of bladder tumour (TURBT) and 2-micron continuous-wave laser resection (2-µm laser) techniques in the management of multiple nonmuscle-invasive bladder cancer (NMIBC), and to investigate long-term effects on tumour recurrence. Methods Patients with multiple NMIBC were randomized to receive TURBT or 2-µm laser in a nonblinded manner. All patients received intravesical chemotherapy with epirubicin (40 mg/40 ml) for 8 weeks, beginning 1 week after surgery, followed with monthly maintenance therapy for 12 months. Three-year follow-up data of preoperative, operative and postoperative management were recorded. Results In total, 120 patients were included: 56 in the TURBT group and 64 in the 2-µm laser group. Intra- and postoperative complications (including bladder perforation, bleeding and irritation) were less frequently observed in the 2-µm laser group compared with the TURBT group. There were no significant differences in first time to recurrence, overall recurrence or occurrence of urethral strictures. Conclusions The 2-µm laser resection method was more effective than TURBT in reducing rates of intra- and postoperative complications, but offered no additional benefit regarding tumour recurrence.
Clinical evaluation of serum cystatin C and creatinine in patients with chronic kidney disease: A meta-analysis
Authors: Zhang Min , Cao Xueying , Cai Guangyan , Wu Di , Wei Ribao , Yuan Xueli , Bai Xueyuan , Liu Shuwen , Chen Xiangmei 
Published: June 2013

Objective Glomerular filtration rate (GFR) is an important indicator of renal function. This meta-analysis aimed to evaluate the diagnostic value of serum cystatin C (CysC) and serum creatinine (SCr) for estimating GFR in patients with chronic kidney disease. Methods Google Scholar, PubMed®, Cochrane Library and China National Knowledge Infrastructure databases were searched, to identify randomized controlled trials that determined the diagnostic value of CysC and SCr, for estimating GFR in patients with chronic kidney disease. Results The inclusion criteria were met by 17 studies (total number of patients with chronic kidney disease, 2521). Meta-analysis showed that when the diagnostic cut-off value of GFR was 80–90 ml/min/1.73 m2, the heterogeneity was modest for CysC ( I2 = 48%, summary sensitivity [SEN] = 0.803, summary specificity [SPE] = 0.821), but there was no heterogeneity for SCr ( I2 = 0.0%, SEN = 0.697, SPE = 0.787). Meta-analysis of the studies demonstrated a significant difference between patients with chronic kidney disease and controls, for CysC and SCr. Conclusions This meta-analysis demonstrated significant correlations between CysC, SCr and GFR. CysC was more sensitive, but less specific, than SCr for the estimation of GFR.
Ultrasound assessment of injury to the posterior ligamentous complex in patients with mild thoracolumbar fractures
Authors: Zhao Jian-Wu , Liu Yan , Yin Ruo-Feng , Wang Jin-Cheng , Yang Yu-Hui , Liu Peng 
Published: June 2013

Objective To assess the value of ultrasonographic imaging of the posterior ligamentous complex (PLC) to diagnose ligamentous injuries, in patients with mild thoracolumbar fractures. Methods Patients with thoracolumbar fractures were included in this prospective study. Patients underwent palpation of the midline of the back, and ultrasonography was performed over the entire thoracolumbar region by an experienced sonographer. A team that included a musculoskeletal radiologist, an orthopaedic surgeon and a sonographer assessed the ultrasound results. Ultrasonographic and magnetic resonance imaging (MRI) findings were jointly evaluated in a subgroup of patients who were able to fund MRI analysis. Conflicts regarding the results were resolved by a majority vote. Results A total of 21 patients participated in the study, all of whom exhibited abnormal ultrasonographic echogenicity on the supraspinous or interspinous ligaments. Three patients were diagnosed with a rupture of the supraspinous ligament. In 15/17 (88.2%) patients, interspinous ligament injuries were detected caudally to the injured vertebrae. Conclusions Ultrasound examination is a reliable complementary diagnostic tool to identify PLC injuries in patients with mild thoracolumbar fractures.
Investigations on the clinical significance of FOXP3 protein expression in cervical oesophageal cancer and the number of FOXP3+ tumour-infiltrating lymphocytes
Authors: Xia Ming , Zhao Miao-qing , Wu Kai , Lin Xiao-yan , Liu Ying , Qin Ye-jun 
Published: June 2013

Objectives Investigations of FOXP3 protein expression in cervical oesophageal cancer cells and the number of FOXP3 + lymphocytes infiltrating tumour tissue were undertaken. Methods FOXP3 protein expression and FOXP3 + tumour-infiltrating lymphocytes were studied immunohistochemically, in cervical oesophageal cancer tissue samples from 42 cases and paracancerous tissue samples from 30 of these cases. Results The percentage of parenchymal cells expressing FOXP3 protein was significantly higher in cancer tissue (42.9%, 18/42) than in paracancerous tissue 6.67% (two of 30). FOXP3 + lymphocyte infiltration was significantly more frequent in cancer (38.1%, 16/42) than in paracancerous (13.33%, four of 30) tissue. FOXP3 protein expression in cancer parenchymal cells in patients with lymph node metastasis was significantly greater than expression in those without lymph node metastasis. FOXP3 protein expression was significantly higher in cancer tissue samples from clinical stage III or IV than those from stage I or II disease. FOXP3 + lymphocyte infiltration of tumours was significantly greater in patients with lymph node metastasis than in those without metastasis. Conclusions Abnormal FOXP3 expression in cervical oesophageal cancer parenchyma and FOXP3 + lymphocyte infiltration might be closely related to metastasis of this cancer by promoting immune escape of the tumour. FOXP3 might be a potential marker for the assessment of postoperative metastasis in cervical oesophageal cancer.
Power, Luck and Ideology – Technological and Institutional Parameters of the Agency Problem for CEOs
Authors: Skott Peter , Guy Frederick 
Published: June 2013

We propose an explanation for the growth of executive pay since the 1980s. New information and communication technologies (ICTs) appear to favor winner-take-all markets and to accentuate firm-level volatility of profits. We show, using an efficiency wage model, that these changes lead to higher executive pay. This is an example of what we have called, in other contexts, power-biased technological change (PBTC). The changes in market structure and the power of CEOs, however, are not only technologically but also institutionally contingent. JEL Classification: D31, J41, O33
Comparison between exfoliated graphite, graphene oxide and multiwalled carbon nanotubes as reinforcing agents of a polyurethane elastomer
Authors: Fernández-d’Arlas Borja , Corcuera Maria A , Eceiza Arantxa 
Published: June 2013

A highly crystalline aliphatic segmented polyurethane (PU) elastomer with 40 wt% hard segment (HS) content, based on 1,6-hexamethylene diisocyanate and 1,4-butanediol as the HS, and a block copolymer of hexamethylene carbonate and polycaprolactone as the soft segment (SS), has been used as the matrix to prepare carbon nanofiller/PU composites by solution casting. Composite films with different loadings of solvent-exfoliated graphene (G)/nanographite, graphene oxide (GO) obtained by the so-called modified Hummers method, and acid-treated multiwalled carbon nanotubes (MWCNT) were obtained and characterised. Tensile test results show that the effectiveness of increasing PU strength follows the trend MWCNT > GO > G. The ductility reduction in all the cases is related to the large sizes of nanofillers in relation to PU hard domains and the hindrance to allow plastic flow of PU SSs by larger fillers.
Leading together, learning together: Music education and music therapy students’ perceptions of a shared practicum
Authors: Ballantyne Julie , Baker Felicity A. 
Published: June 2013

The health benefits of musical engagement extend across the lifespan, with research documenting developmental and quality of life outcomes in senior adulthood. Whilst the psychological functions of music include three broad domains: cognitive, emotional and social, the social factors of music consumption have been, for the most part, ignored. This project is predicated on the understanding that students “construct” their own knowledge through engagement with others. It also reflects the belief that it is possible to link the world of learning with a world of action through a reflective process with small cooperative learning groups. This article reports on a collaborative creativity leadership project implemented by music therapy and music education students. In particular, it explores the perceptions of the students as they employed a teaching/therapeutic intervention with ageing participants from a local private retirement village. The project involved lyric rewriting and singing performance. Drawing on the students’ reflective journals and interview transcripts, four themes emerged relating to students’ perceptions of the learning experience. These themes were: learning about facilitating, learning about self, learning about the musical process, and learning about the context/ageing. Each of these themes is explored before conclusions about the process of leading a creative collaboration are drawn. The implications of this analysis extend beyond the context of a retirement village, and into various educational and therapeutic contexts where creative collaboration is facilitated.
Developing and evaluating cognitive remediation therapy (CRT) for adolescents with anorexia nervosa: A feasibility study
Authors: Dahlgren Camilla Lindvall , Lask Bryan , Landrø Nils-Inge , Rø Øyvind 
Published: June 2013

Background: Cognitive Remediation Therapy (CRT) aims at improving neuropsychological weaknesses and associated thinking styles in patients with anorexia nervosa (AN). It has only recently been developed for adolescents with AN, and evidence of its applicability for this particular patient group is limited. This study aimed to test the feasibility of individually tailored and delivered CRT for young females with AN. Methods: A sample of 20 in- and outpatients (13–18 years) with AN participated in once- or twice weekly individual CRT sessions. The CRT materials used were available in a “CRT Resource Pack.” Feasibility was assessed with regards to the recruitment process, the delivery of the intervention, the materials used and clinical experiences. Results: Overall results indicate that the intervention was feasible with regards to (a) the recruitment of both in- and outpatients, (b) individual tailoring and delivery, (c) the CRT materials adapted to suit young females with AN, and (d) the acceptability for clinicians involved in the study. There were no voluntary dropouts, with 19 of 20 patients completing the entire course of treatment. Conclusions: The findings have implications for the refinement of CRT for the youngest AN population, and strengthens our understanding of the core components in the development and evaluation of novel interventions targeting AN. This study will help inform the design of a subsequent randomized controlled trial.
Impact of Poor Retention in HIV Medical Care on Time to Viral Load Suppression
Authors: Crawford Timothy N. , Sanderson Wayne T. , Thornton Alice 
Published: June 2013

Objective: The purpose of this study was to evaluate how poor retention in HIV care impacts time to viral suppression after initiating highly active antiretroviral therapy. Methods: A retrospective cohort study design, employing a medical chart review, was conducted at an academic infectious disease clinic at the University of Kentucky. Patients seeking care between 2003 and 2011 were included in the study. A log-normal model was employed to determine the factors associated with time to viral suppression. Results: Of the 532 patients in the study, 426 (80.1%) patients were virally suppressed. Controlling for insurance status, race, baseline CD4 counts, and viral loads, the expected time to viral suppression for nonoptimal retainers was longer compared to optimal retainers (100% retained in care; time ratio: 2.04; 95% confidence interval: 1.40-2.90). Conclusion: Researchers should continue to study the impact of retention on clinical outcomes and strategies to improve retention and reengage those lost to follow-up back into care.
Risk Factors for Lower Extremity Tendinopathies in Military Personnel
Authors: Owens Brett D. , Wolf Jennifer Moriatis , Seelig Amber D. , Jacobson Isabel G. , Boyko Edward J. , Smith Besa , Ryan Margaret A.K. , Gackstetter Gary D. , Smith Tyler C. ,   for the Millennium Cohort Study Team, Bagnell Melissa , Creaven Gina , Crum-Cianflone Nancy , Davies James , Granado Nisara , Hernando Dennis , Horton Jaime , Jones Kelly , LeardMann Cynthia , Lee William , Linfesty Michelle , Lynch Gordon , McMaster Hope , Medina-Torne Sheila , Pietrucha Amanda , Powell Teresa , Sausedo Kari , Sheppard Beverly , Snell Katherine , Speigle Steven , White Martin , Whitmer James , Wong Charlene 
Published: June 2013

Background: Overuse injuries have a significant impact on United States military service members, but research to date has been limited in its ability to assess occupational and behavioral risk factors. Hypothesis/Purpose: To prospectively identify risk factors for the development of lower extremity tendinopathy and plantar fasciitis in United States military personnel. Study Design: Descriptive epidemiology study. Methods: Baseline data from the Millennium Cohort Study, a long-term observational cohort of military personnel, were utilized. Service members were enrolled in the cohort in 2001, 2004, and 2007. A total of 80,106 active-duty personnel were followed over 1 year for the development of patellar tendinopathy, Achilles tendinopathy, and plantar fasciitis. Regression analyses were used to estimate significant associations between each tendinopathy, plantar fasciitis, and demographic, behavioral, and occupational characteristics. Results: Using medical records, 450 cases of Achilles tendinitis, 584 cases of patellar tendinopathy, and 1228 cases of plantar fasciitis were identified. Recent deployment was associated with an increased risk for developing plantar fasciitis (adjusted odds ratio [AOR], 1.27; 95% confidence interval [CI], 1.04-1.56). Moderate weekly alcohol consumption was marginally associated with an increased risk for Achilles tendinopathy (AOR, 1.33; 95% CI, 1.00-1.76). Overweight or obese individuals were more likely to develop Achilles tendinopathy and plantar fasciitis. Conclusion: Lower extremity tendinopathies and plantar fasciitis are common among military service members, and this study identified several modifiable risk factors for their occurrence. These potential risk factors could serve as the focus for future preventive and intervention studies.