bluuebunny/crossref_metadata_2025_split huggingface dataset:
Job resources and employee engagement: a cross-national study
Authors: Farndale Elaine , Murrer Inge 
Published: July 2015

Purpose– In light of increasing globalization of workforces, the purpose of this paper is to explore the moderating effect of country on the relationship between job resources and employee engagement.Design/methodology/approach– Questionnaire responses from 19,260 employees of a large multinational financial services corporation in Mexico, the Netherlands, and the USA are analyzed using regression analyses and a study of effect sizes.Findings– The results show that certain job resources (financial rewards, team climate, participation in decision making) positively influence engagement in all three countries. However, the study also shows distinctions between the strength of relationships between these job resources and engagement per country which are explained through cross-cultural theorizing.Research limitations/implications– National-level variations in relationships between job resources and employee engagement are evidenced, and these can be explained to a considerable extent by applying a cross-cultural theoretical lens.Practical implications– The study highlights the importance for firms to be aware of and learn from the equivalence of constructs and their relationships across countries: although similar relationships were observed across the three countries studied here, the differences may be sufficient to require alternate approaches to appropriate job resources to engender engagement.Originality/value– Although there has been considerable empirical investigation into the relationship between job resources and engagement, little has focussed on different national settings simultaneously.
How do working mothers negotiate the work-home interface?
Authors: Araujo Bruno Felix von Borell de , Tureta Cesar Augusto , Araujo Diana Abreu von Borell de 
Published: July 2015

Purpose– The purpose of this paper is to explore the tactics that mid-career professional working mothers use to improve their work-home balance.Design/methodology/approach– The qualitative study used in-depth interviews with 63 Brazilian professional working mothers aged between 37 and 55, having at least one child under the age of 18, and living in dual-career households. The interviews were content analyzed.Findings– The study reported four dimensions of boundary work tactics (behavioral, temporal, physical, and communicative) that mid-career working mothers adopted to construct a satisfying level of segmentation or integration between work and home.Research limitations/implications– The study suggests individual tactics for actively constructing a generalized work-home state that can be adopted by working mothers. Additionally, the authors suggest that HR managers should develop work-home balance programs that provide policies that adjust to the work-home boundary preferences for those mothers who want to integrate and segment these domains.Social implications– The authors hope this study can help mid-career working mothers to understand how they can interact actively with others in such a way that they can better answer their work and home demands.Originality/value– This study was the first to use boundary work tactics theory to explore how mid-career professional working mothers improve their work-home balance.
Suboptimal dietary intake is associated with cardiometabolic risk factors in women with polycystic ovary syndrome
Authors: Hart Kathryn , Barr Suzanne , Reeves Sue , Sharp Kay , Jeanes Yvonne 
Published: July 2015

AbstractAimPolycystic ovary syndrome (PCOS) is the most prevalent endocrine disorder in women and confers a substantial health burden. It is important to explore modifiable extrinsic factors that contribute to disease risk. The aim of the present study was to compare the dietary intake, physical activity and physiological characteristics of women with PCOS with those of controls to identify lifestyle behaviours associated with known cardiometabolic risk factors.MethodsA seven‐day food and activity diary was completed and anthropometric and biomarkers of type 2 diabetes mellitus and cardiovascular disease risk were measured in 38 women with PCOS, and 30 controls, matched for age and body mass index.ResultsSimilar energy intakes and activity levels were observed between groups. Percentage energy intakes from total, saturated and monounsaturated fats were significantly higher (P = 0.008, P = 0.012 and P = 0.003, respectively) and % energy from carbohydrate was significantly lower (P < 0.001) in participants with PCOS compared with controls (P < 0.001). Insulin levels, two hours after a glucose challenge, were significantly higher in PCOS participants compared with controls (P = 0.029). Increased dietary glycaemic index appeared to be associated with a more negative biochemical profile in women with PCOS compared to controls, being significantly associated with an increased waist circumference and LDL‐cholesterol and decreased HDL‐cholesterol.ConclusionsThe present study has identified suboptimal dietary patterns in women with PCOS, and highlighted dietary factors associated with cardiometabolic risk factors that warrant monitoring in both lean and obese women with PCOS.
Influence of Tricuspid Bioprosthetic Mitral Valve Orientation Regarding the Flow Field Inside the Left Ventricle: In Vitro Hydrodynamic Characterization Based on 2D PIV Measurements
Authors: Bazan Ovandir , Ortiz Jayme P. , Fukumasu Newton K. , Pacifico Antonio L. , Yanagihara Jurandir I. 
Published: July 2015

AbstractThe flow patterns of a prosthetic heart valve in the aortic or mitral position can change according to its type and orientation. This work describes the use of 2D particle image velocimetry (PIV) applied to the in vitro flow fields characterization inside the upper part of a left ventricular model at various heart rates and as a function of two orientations of stented tricuspid mitral bioprostheses. In the ventricular model, each mitral bioprosthesis (27 and 31 mm diameter) was installed in two orientations, rotated by 180°, while the aortic bileaflet mechanical valve (27 mm diameter) remained in a fixed orientation. The results (N = 50) showed changes in the intraventricular flow fields according to the mitral bioprostheses positioning. Also, changes in the aortic upstream velocity profiles were noticed as a function of mitral orientations.
Real‐Time Visualization of Platelet Interaction With Micro Structured Surfaces
Authors: Gester Kathrin , Birtel Stephan , Clauser Johanna , Steinseifer Ulrich , Sonntag Simon Johannes 
Published: July 2015

AbstractImproving the hemocompatibility of artificial implants by micro structuring their surfaces has shown promising results, but the mechanisms which lead to this improvement are not yet understood. Therefore, we built a test setup for real‐time visualization of platelet interaction with a plain and two micro structured surfaces. The micro structures, defined by the distance of the plain surface area between the structures, were chosen to be 3 and 30 μm, representing a positive and a negative effect on the hemocompatibility. The main part of the test setup was a flow chamber containing films of low density polyethylene (LDPE) with the differently structured surfaces. For different wall shear stresses, no considerable differences were observed in the platelet‐surface interaction for all surface types. Whereas, major differences in flow behavior were observed when comparing the surfaces to each other. The platelets “rolled” along the smooth surface, being in constant contact with the surface material. Although the platelets “rolled” over the surface with small structures as well, they were only in contact with the tips of the structure and therefore had less surface contact with the foreign material. The increased distance and height of the structures of the last surface led to a trapping of platelets between the structures. This resulted in a longer contact time with the foreign material as well as a larger contact area, which both increase the risk of platelet activation, adhesion, and finally clotting. Our results showed the mechanisms which lead to these effects and thus revealed why micro structuring of surfaces impacts the hemocompatibility. Furthermore, we established a test setup which can be used for future investigations on the platelet‐structure interactions.
A J‐Shaped Association Between Serum Uric Acid Level and Allograft Outcomes After Living Donor Kidney Transplantation
Authors: Oh Il Hwan , Kim Jeong Eun , Lee Chang Hwa , Kim Gheun‐Ho , Park Joon‐Sung 
Published: July 2015

AbstractHyperuricemia following kidney transplantation (KT) may contribute to a decline in allograft renal function, but be affected by KT‐related confounding factors. Some studies have even suggested that a reduction in serum uric acid (UA) is associated with poor patient outcomes. Thus, we retrospectively analyzed the impact of serum UA on allograft outcomes in 281 KT recipients. KT recipients were divided into five groups according to serum UA level (mg/dL): Group I (n = 46), ≤ 5; Group II (n = 62), >5 and ≤6; Group III (n = 70), >6 and ≤7; Group IV (n = 53), >7 and ≤8; Group V (n = 50), >8. Regression analysis showed that serum UA level was significantly associated with future allograft function. In a Kaplan–Meier analysis, the dialysis‐free survival of Group II recipients was better than that of the other groups (Group I, 140 ± 5 months; Group II, 208 ± 7 months; Group III, 148 ± 4 months; Group IV, 185 ± 12 months; Group V, 164 ± 11 months; P = 0.0164). In Cox proportional hazard models adjusting for estimated glomerular filtration rate, the relative risk of allograft loss still tended to be elevated in Group I (HR=3.417, 95% CI 1.138–10.258) and Group V (HR=2.793, 95% CI 1.108–7.041), using Group II as the reference. Our results suggest that there is a J‐shaped association between serum UA levels and allograft outcomes in living donor KT recipients.
Newborn manikin study shows that physicians often fail to detect correct lung compliance when using a self‐inflating bag
Authors: Boldingh Anne Marthe , Solevåg Anne Lee , Benth Jūratė Šaltytė , Klingenberg Claus , Nakstad Britt 
Published: July 2015

AbstractAimRecognising changes in lung compliance can help clinicians to adjust initial inflations during resuscitation at birth. We examined whether physicians sensed low and normal compliance with a self‐inflating bag before and after an educational intervention that used a manikin connected to a newborn lung simulator.MethodsWe asked 43 physicians with neonatal duties to perform two low compliance ventilation attempts and two normal‐compliance ventilation attempts in a randomised order at baseline and after the educational intervention, with 34 taking part in a retest three months later.ResultsThe physicians correctly recognised low and normal compliance in 71% and 66% of the ventilations at baseline, 80% and 66% of the ventilations after the intervention and 74% and 81% at retest. Correct recognition of normal compliance improved from baseline to retest (p = 0.04). Ventilations in low‐ vs normal‐compliance settings resulted in lower tidal volumes (4.4 vs 23.0 mL, p < 0.001), lower ventilation rates (42 vs 51, p < 0.001) and higher peak inflating pressure (35.2 vs 31.4 cmH2O, p < 0.001).ConclusionAround one in four physicians failed to recognise correct compliance levels when using a self‐inflating bag and showed limited improvement after an educational intervention. Ventilations in a low‐compliance setting resulted in suboptimal ventilation.
Electrical stimulation therapy of the lower oesophageal sphincter for refractory gastro‐oesophageal reflux disease – interim results of an international multicentre trial
Authors: Kappelle W. F. W. , Bredenoord A. J. , Conchillo J. M. , Ruurda J. P. , Bouvy N. D. , van Berge Henegouwen M. I. , Chiu P. W. , Booth M. , Hani A. , Reddy D. N. , Bogte A. , Smout A. J. P. M. , Wu J. C. , Escalona A. , Valdovinos M. A. , Torres‐Villalobos G. , Siersema P. D. 
Published: July 2015

SummaryBackgroundA previous single‐centre study showed that lower oesophageal sphincter electrical stimulation therapy (LES‐EST) in gastro‐oesophageal reflux disease (GERD) patients improves reflux symptoms and decreases oesophageal acid exposure.AimTo evaluate safety and efficacy of LES‐EST in GERD patients with incomplete response to proton pump inhibitors (PPIs) in a prospective, international, multicentre, open‐label study.MethodsGERD patients, partially responsive to PPIs, received LES‐EST. GERD health‐related quality of life (GERD‐HRQL), daily symptom diaries, quality of life scores, oesophageal acid exposure, and LES resting and residual pressure were measured before and after initiation of LES‐EST. Stimulation sessions were optimised based on residual symptoms and oesophageal acid exposure.ResultsForty‐four patients were enrolled and 6‐month data from 41 patients are available. Hiatal repair was performed in 16 patients. One device‐related, one procedure‐related and one unrelated severe adverse event were reported. GERD‐HRQL improved from 31.0 (IQR 26.2–36.8) off‐PPI and 16.5 (IQR 9.0–22.8) on‐PPI to 4 (IQR 1–8) at 3‐month and 5 (IQR 3–9) at 6‐month follow‐up (P < 0.0001 vs. on‐ and off‐PPI). Oesophageal acid exposure (pH < 4.0) improved from 10.0% (IQR 7.5–12.9) to 3.8% (IQR 1.9–12.3) at 3 months (P = 0.0027) and 4.4% (IQR 2.2–7.2) at 6 months (P < 0.0001).ConclusionsThese interim results show an acceptable safety record of LES‐EST to date, combined with good short‐term efficacy in GERD patients who are partially responsive to PPI therapy. A remarkable reduction in regurgitation symptoms, without the risk of intervention‐requiring dysphagia may prove to be an advantage compared with other anti‐reflux procedures. ClinicalTrials.gov Identifier: NCT01574339.
Cytoskeletal and mitochondrial properties of bovine oocytes obtained by Ovum Pick‐Up: the effects of follicle stimulation and in vitro maturation
Authors: Somfai Tamás , Matoba Satoko , Inaba Yasushi , Nakai Michiko , Imai Kei , Nagai Takashi , Geshi Masaya 
Published: July 2015

AbstractFollicle stimulation by follicular stimulating hormone (FSH) is known to improve developmental competence of bovine oocytes obtained by Ovum Pick‐Up (OPU); however, the exact factors in oocytes affected by this treatment have remained unclear. We compared in vitro matured (IVM) oocytes obtained at the immature stage from cows by OPU either without or with stimulation with FSH (non‐stimulated and stimulated OPU, respectively) to those obtained by superstimulation and in vivo maturation in terms of cytoskeleton morphology, mitochondrial distribution, intracellular adenosine triphosphate (ATP) content and H2O2 levels at the metaphase‐II stage and intracellular Ca2+ levels after in vitro fertilization (IVF). Confocal microscopy after immunostaining revealed reduced size of the meiotic spindle, associated with increased tendencies of microfilament degradation and insufficient mitochondrial re‐distribution in non‐stimulated OPU‐derived IVM oocytes compared with those collected by stimulated OPU, which in turn resembled in vivo matured oocytes. However, there was no difference in mitochondrial functions between oocytes obtained by stimulated or non‐stimulated OPU in terms of ATP content, cytoplasmic H2O2 levels, base Ca2+ levels and the frequencies and amplitudes of Ca2+ oscillations after IVF. Larger size of metaphase spindles in oocytes obtained by stimulated OPU may reflect and potentially contribute to their high developmental competence.
Genetic analysis of fat‐to‐protein ratio, milk yield and somatic cell score of Holstein cows in Japan in the first three lactations by using a random regression model
Authors: Nishiura Akiko , Sasaki Osamu , Aihara Mitsuo , Takeda Hisato , Satoh Masahiro 
Published: July 2015

AbstractWe estimated the genetic parameters of fat‐to‐protein ratio (FPR) and the genetic correlations between FPR and milk yield or somatic cell score in the first three lactations in dairy cows. Data included 3 079 517 test‐day records of 201 138 Holstein cows in Japan from 2006 to 2011. Genetic parameters were estimated with a multiple‐trait random regression model in which the records within and between parities were treated as separate traits. The phenotypic values of FPR increased soon after parturition and peaked at 10 to 20 days in milk, then decreased slowly in mid‐ and late lactation. Heritability estimates for FPR yielded moderate values. Genetic correlations of FPR among parities were low in early lactation. Genetic correlations between FPR and milk yield were positive and low in early lactation, but only in the first lactation. Genetic correlations between FPR and somatic cell score were positive in early lactation and decreased to become negative in mid‐ to late lactation. By using these results for genetic evaluation it should be possible to improve energy balance in dairy cows.
Bortezomib, thalidomide and dexamethasone, with or without cyclophosphamide, for patients with previously untreated multiple myeloma: 5‐year follow‐up
Authors: Ludwig Heinz , Greil Richard , Masszi Tamas , Spicka Ivan , Shpilberg Ofer , Hajek Roman , Dmoszynska Anna , Paiva Bruno , Vidriales María‐Belén , Esteves Graca , Stoppa Anne Marie , Robinson Don , Chaturvedi Shalini , Ataman Ozlem , Enny Christopher , Feng Huaibao , van de Velde Helgi , Viterbo Luisa 
Published: July 2015

SummaryThis follow‐up extension of a randomised phase II study assessed differences in long‐term outcomes between bortezomib‐thalidomide‐dexamethasone (VTD) and VTD‐cyclophosphamide (VTDC) induction therapy in multiple myeloma. Newly diagnosed patients (n = 98) were randomised 1:1 to intravenous bortezomib (1·3 mg/m2; days 1, 4, 8, 11), thalidomide (100 mg; days 1–21), and dexamethasone (40 mg; days 1–4, 9–12), with/without cyclophosphamide (400 mg/m2; days 1, 8), for four 21‐day cycles before stem‐cell mobilisation/transplantation. After a median follow‐up of 64·8 months, median time‐to‐next therapy was 51·8 and 47·9 months with VTD and VTDC, respectively. Type of subsequent therapy was similar in both arms. After adjusting for asymmetric censoring, median time to progression was not significantly different between VTD and VTDC [35·7 vs. 34·5 months; Hazard ratio (HR) 1·26, 95% confidence interval: 0·76–2·09; P = 0·370]. Five‐year survival was 69·1% and 65·3% with VTD and VTDC, respectively. When analysed by minimal residual disease (MRD) status, overall survival was longer in MRD‐negative versus MRD‐positive patients with bone marrow‐confirmed complete response (HR 3·66, P = 0·0318). VTD induction followed by transplantation provides long‐term disease control and, consistent with the primary analysis, there is no additional benefit from adding cyclophosphamide. This study was registered at ClinicalTrials.gov (NCT00531453).
Flexibility in Bilingual Infants' Word Learning
Authors: Graf Estes Katharine , Hay Jessica F. 
Published: July 2015

The present experiments tested bilingual infants' developmental narrowing for the interpretation of sounds that form words. These studies addressed how language specialization proceeds when the environment provides varied and divergent input. Experiment 1 (N = 32) demonstrated that bilingual 14‐ and 19‐month‐olds learned a pair of object labels consisting of the same syllable produced with distinct pitch contours (rising and falling). Infants' native languages did not use pitch contour to differentiate words. In Experiment 2 (N = 16), 22‐month‐old bilinguals failed to learn the labels. These results conflict with the developmental trajectory of monolinguals, who fail to learn pitch contour contrasts as labels at 17–19 months (Hay, Graf Estes, Wang, & Saffran, 2015). Bilingual infants exhibited a prolonged period of flexibility in their interpretation of potential word forms.
Resolving future fire management conflicts using multicriteria decision making
Authors: Driscoll Don A. , Bode Michael , Bradstock Ross A. , Keith David A. , Penman Trent D. , Price Owen F. 
Published: July 2015

AbstractManagement strategies to reduce the risks to human life and property from wildfire commonly involve burning native vegetation. However, planned burning can conflict with other societal objectives such as human health and biodiversity conservation. These conflicts are likely to intensify as fire regimes change under future climates and as growing human populations encroach farther into fire‐prone ecosystems. Decisions about managing fire risks are therefore complex and warrant more sophisticated approaches than are typically used. We applied a multicriteria decision making approach (MCDA) with the potential to improve fire management outcomes to the case of a highly populated, biodiverse, and flammable wildland–urban interface. We considered the effects of 22 planned burning options on 8 objectives: house protection, maximizing water quality, minimizing carbon emissions and impacts on human health, and minimizing declines of 5 distinct species types. The MCDA identified a small number of management options (burning forest adjacent to houses) that performed well for most objectives, but not for one species type (arboreal mammal) or for water quality. Although MCDA made the conflict between objectives explicit, resolution of the problem depended on the weighting assigned to each objective. Additive weighting of criteria traded off the arboreal mammal and water quality objectives for other objectives. Multiplicative weighting identified scenarios that avoided poor outcomes for any objective, which is important for avoiding potentially irreversible biodiversity losses. To distinguish reliably among management options, future work should focus on reducing uncertainty in outcomes across a range of objectives. Considering management actions that have more predictable outcomes than landscape fuel management will be important. We found that, where data were adequate, an MCDA can support decision making in the complex and often conflicted area of fire management.
Navigating Disruptive Innovation in Undergraduate Business Education
Authors: Behara Ravi S. , Davis Mark M. 
Published: July 2015

ABSTRACTThe undergraduate business education landscape is dramatically changing and will continue to do so for the foreseeable future. Many of the changes are being driven by increasing costs, advances in technology, rapid globalization, and an increasingly diverse workforce and customer base, and are occurring simultaneously in both the business world and higher education. This is especially true for undergraduate business education in which alternative models to the traditional four‐year curriculum continue to emerge. Using Christensen's theory of disruptive innovation as a framework, we develop a set of recommendations to help undergraduate business education navigate the disruptions it faces by adopting a “pragmatic liberal” approach. This approach offers a direct contrast to the decades of limited success that business schools have had integrating liberal education and business education.