bluuebunny/crossref_metadata_2025_split huggingface dataset:
Consider the Translator : traduire la non-fiction de David Foster Wallace
Authors: Vivier Sigolène 
Published: June 2024

Cet article se penche sur la posture énonciative construite dans l’œuvre de non-fiction de David Foster Wallace, et ce que celle-ci implique dans le processus traductif. En effet, le discours wallacien commente sans cesse sa propre construction, et cette langue réflexive, en retour perpétuel sur elle-même, déstabilise notre perception du réel en train de s’écrire. À ce titre, la non-fiction de Wallace constitue un projet d’énonciation spécifique, qui implique de se camper soi-même en personnage de l’exégèse. Cette posture auctoriale singulière, entre effacement et théâtralisation de soi, fiabilité et faillibilité, appelle en retour une réflexion sur la posture du traducteur – choisira-t‑il de déjouer le risque de la glose ou embrassera-t‑il la pulsion exégétique qui figure précisément au cœur du dispositif textuel ? Les problèmes traductologiques examinés ne concerneront ainsi pas tant ce qui résiste à la traduction que le degré de minutie dans lequel le traducteur choisira de s’engager pour expliciter le foisonnement du texte source. Incorporer cette réflexivité au geste traductif, que l’on peut déjà comprendre par essence comme un retour critique sur le texte, reviendrait alors à actualiser le projet de Berman, où la traduction assumera de devenir « critique et commentaire d’elle-même ».
Orwell au tamis : autobiographie, ethnographie et fiction en traduction
Authors: Béghain Véronique 
Published: June 2024

Cet article s’intéresse aux difficultés spécifiques que pose la traduction des récits autobiographiques d’Orwell et il est plus particulièrement centré sur The Road to Wigan Pier (1937). On privilégie, dans ce cadre, l’examen des contraintes liées à l’hybridité générique du livre. La première partie, une enquête sur les conditions de vie des chômeurs et des mineurs du Nord de l’Angleterre, relève de l’enquête sociologique. La deuxième partie, au matériau beaucoup plus hétérogène, peut se lire comme une « autobiographie culturelle », conjuguée à un essai polémique sur les causes de l’échec du socialisme en Angleterre. On examine notamment à partir du corpus que constitue The Road to Wigan Pier : les problèmes posés par la traduction du titre-millefeuille de l’œuvre et par celle du célèbre concept de « common decency » ; les contraintes liées à la dimension ethnographique du livre, à sa visée politique et à sa tonalité polémique.
Des incertitudes levées sur les reliques de Lothéa (forêt de Carnoët, Quimperlé, Finistère)
Authors: Soto José Gomez de , Nicolas Clément , Pailler Yvan 
Published: June 2024

Le caveau du tumulus de Lothéa en forêt de Quimperlé (Finistère) fut fouillé en 1843. Son mobilier subit divers aléas entre sa remise au musée de l’Hôtel de Cluny à Paris aussitôt après la fouille et la dévolution de l’essentiel de la collection au musée des Antiquités nationales de Saint-Germain-en-Laye (MAN) en 1887. Il faudra attendre 1974 pour disposer d’une étude exhaustive de ce mobilier, auquel s’étaient trouvées adjointes quelques pièces d’autres origines conservées dans diverses collections ou présentées dans des publications fautives. La découverte de correspondances inédites du fouilleur, Arthur Boutarel, permit une mise au point des connaissances par un article publié en 2013 dans Gallia Préhistoire. Restait cependant en suspens la question d’un talon conique en bronze, typologiquement et technologiquement incompatible avec la date de la tombe, probablement ajouté à la collection à date inconnue au cours du xixe siècle. Un retour critique aux informations données par la documentation ancienne a permis de compléter l’inventaire du mobilier funéraire par un poignard actuellement perdu, et le talon en bronze a pu être identifié comme un embout de hampe de lance italique de l’âge du Fer indiscutablement intrus.
Effect of Training of Adolescents on Household Environmental Safety from Childhood Injuries in a Rural Area of Delhi
Authors: Banerjee Bratati 
Published: June 2024

Introduction:
The environment poses an important risk in the causation of injuries in children. Simple measures in improving the safety of the domestic and peri-domestic environment can go a long way in preventing injuries. This study was conducted to assess the effect of training of the adolescents in the families, on the household environmental safety regarding childhood injuries.

Materials and Methods:
A pre- and post-intervention study was conducted over 16 months, on 116 families of two villages of Delhi. Data were collected regarding domestic and peri-domestic environments along with danger points with respect to injuries, of the enrolled houses, during the pre- and post-intervention phases of 4 months each. The intervention comprised training of the eldest adolescent of the family, on causes of common injuries and role of environment in injury causation. Scores were assigned to all relevant aspects, and the total environmental safety scores were calculated. The comparison was made between pre- and post-intervention scores of the two areas.

Results:
Environmental safety scores were more than 70% in both areas at the baseline with no difference between the two areas. In the intervention area, there was statistically significant improvement of scores after the intervention, in the domestic environment and danger signs within the houses.

Conclusion:
Training adolescents about the prevention of injuries and motivating them to remain vigilant over domestic environment are effective in bringing about significant change in the household environment with regard to safety from injuries in children. Repeated visits by health workers also increase awareness and change the household environment making it safer for children.
Seroprevalence and Risk Factors Associated with Leptospirosis in High-Risk Occupational Groups in the State of Gujarat as Determined by IgM ELISA and MAT Test: A Cross-Sectional Study
Authors: Mevada Yogendra , Vinod Kumar Kirubakaran , Balamurgan Vinayagamurthy , Chavhan Snehal , Kumar Jitendra , Palkhade Rajendra 
Published: June 2024

Background:
Leptospirosis is a reemerging zoonosis affecting humans and animals worldwide in tropical and subtropical countries. The study was conducted to estimate the seroprevalence of leptospirosis in high-risk occupational groups (cattle farm workers, poultry farm workers, and slaughterhouse workers) in the state of Gujarat and to determine related risk factors for leptospirosis.

Methods:
Using an interview-guided questionnaire, a cross-sectional study was conducted involving 123 people in high-risk occupational groups (namely, cattle farm workers, poultry farm workers, and slaughterhouse workers) from five districts of the state of Gujarat, India. The participants’ serum samples were screened for antileptospiral antibodies by using Immunoglobulin G (IgG) and Immunoglobulin M (IgM) enzyme-linked immunosorbent assays (ELISAs) followed by a microscopic agglutination test (MAT). The Chi-square (χ2) test and odds ratio were calculated using IBM SPSS Statistics for Windows, version 22 (IBM Corp., Armonk, N.Y., USA) to ascertain the associated risk factors.

Results:
Regarding demographic information, this study included 104 men and 19 women in high-risk occupational groups. The overall seroprevalence of antileptospiral antibodies in these high-risk workers was 46.3%. The seroprevalence was the highest among poultry farm workers (56.6%), followed by cattle farm workers (54.5%) and slaughterhouse workers (25.6%). The MAT in combination with IgM is adequate for the serological diagnosis of leptospirosis, but we have also employed IgG ELISA to understand the chronic infection in these high-risk occupational groups as exposure was both past and present. Tests were conducted for antibodies against various Leptospira serovars in the major serogroups; frequent serovars included Hurstbridge, Panama, Javanica, Tarassovi, Copenhageni, Pomona, and Weaveri, among others. The significant (P < 0.05) risk factors associated with leptospirosis in these high-risk occupations reported to be living in field areas, the presence of livestock in the neighborhood, working in slaughterhouses, drinking water from natural water resources, contact with animals such as dogs or livestock, and wounds during occupational practice.

Conclusion:
Considering the high seroprevalence of leptospirosis, high-risk occupational groups should be regularly screened for potential development of the fatal disease. Hurstbridge was found to be the most prevalent serovar in the studied population, followed by Panama, Javanica, and Tarassovi.
Plasma Cell Infiltrate in Liver Allograft Biopsy: Clinical and Histological Implications
Authors: Agrawal Neha , Rastogi Archana , Bihari Chhagan , Choudhury Ashok , Pamecha Viniyendra 
Published: June 2024

Introduction:
The relevance of plasma cells in the allograft liver is of utmost importance and objective assessment of these infiltrates and correlation with other ancillary findings needs to be evaluated.

Materials and Methods:
Three hundred and sixty-eight graft liver biopsies received in the department from 2012 to 2022 and 115 allograft liver biopsies with histopathological diagnosis of rejection were selected. Based on plasma cells percentage in the portal tracts, the biopsies were divided into three groups: Group 1 showing not more than an occasional plasma cell, Group 2 showing <10% plasma cells, and Group 3 showing >10% plasma cells. Rejection activity index (RAI), portal/lobular inflammation, interface activity, subendothelial inflammation (portal and central vein), duct damage/loss, presence of cholestasis, apoptosis, perivenulitis, necrosis, rosette along with serial liver function tests (LFTs), and patient status at 1 year of follow-up were recorded and compared between the groups.

Results:
Plasma cell infiltrates were observed in 52.6% of the specimens, with the mean percentage of plasma cells in the infiltrates being 4.9. Increased plasma cell infiltrates were associated with higher RAI scores, marked duct damage, marked portal and central vein endotheliitis, marked portal inflammation, and presence of interface activity. Higher levels of transaminitis were recorded at the time of biopsy, but no significant association was observed in the fall of serial LFTs over a 2-week period with the presence of plasma cells.

Conclusion:
Identifying plasma cell infiltrates in liver allografts can serve as a clue toward increased severity of rejection in liver allograft biopsies. Further studies with emphasis on correlation with the clinical outcome and response to treatment are needed to validate its utility as an objective tool.
Urinary Mitochondrial DNA Induces an Inflammatory Response in Peripheral Blood Mononuclear Cells
Authors: Yadav Brijesh , Prasad Narayan , Kushwaha Ravi Shanker , Singh Ankita , Yadav Deependra , Bhadauria Dharmendra Singh , Kaul Anupma 
Published: June 2024

Background:
Mitochondria are semiautonomous cell organelles having its own nucleic acid. Mitochondrial DNA (Mt-DNA) remain in hypomethylated (CpG) state and impose an immunogenic response by binding to the toll-like receptor (TLR-9) through the NF-kB pathway. Innate immune cells recognize the hypomethylated pattern of mt-DNA and quickly trigger the innate immune response. The immunomodulatory effects of urinary mt-DNA derived from renal transplant recipients with COVID-19-associated acute kidney injury (AKI) have not been studied.

Materials and Methods:
Healthy donor peripheral blood mononuclear cell (PBMC) was cultured with the urinary Mt-DNA derived from the renal transplant recipients, who previously developed SARS-CoV-2 infection associated AKI. Cell activation was measured by the flow cytometry. In cell pellets, interleukin IL-6, IL-10, and Myd88, TLR-9 mRNA transcript expression was measured by the reverse transcription polymerase chain reaction. The IL-6 and IL-10 cytokine levels were measured by the enzyme-linked immunosorbent assay in culture supernatants.

Results:
The urinary mitochondrial DNA (umt-DNA) significantly induces the activation of > 75% of PBMCs. The m-RNA transcript expression of the inflammatory gene in control versus umt-DNA treated PBMCs was for IL-6 (0.99 ± 0.05 vs. 2.18 ± 1.15 au; P = 0.004), MYD88 was (1.00 ± 0.05 vs. 1.55 ± 0.31; P < 0.001), TLR-9 (1.00 ± 0.05 vs. 3.33 ± 1.37 au; P < 0.001) was upregulated, and the IL-10 (1.00 ± 0.13 vs. −1.73 ± 0.58; P < 0.001) level was downregulated. However, in PBMC culture supernatants, IL-6 level in control versus umt-DNA-treated groups were (37.50 ± 13.79 vs. 186.9 ± 15.50 pg/mL; P < 0.001), which was significantly higher in umt-DNA-treated groups and the IL-10 (8.80 ± 2.16 vs. 7.60 ± 3.12 pg/mL; P = 0.32) level was similar between the control- and umt-DNA-treated groups.

Conclusions:
Urinary Mt-DNA significantly induces the inflammatory cytokine IL-6 secretion from the PBMCs through the Myd88-dependent pathway.
Identification of Key Genes Associated with Polycystic Ovarian Syndrome and Endometrial and Ovarian Cancer through Bioinformatics
Authors: Raulo Karishma , Qazi Sahar 
Published: June 2024

ABSTRACT

Background:
Polycystic ovary syndrome (PCOS), a common endocrine disorder, is linked to increased risks of endometrial cancer (EC) and ovarian cancer (OC). Our study utilises bioinformatics analysis to identify shared gene signatures and elucidate biological processes between EC and OC and PCOS.

Aim:
The objective of this research is to unveil the common molecular landscape shared by PCOS and EC and OC.

Settings and Design:
An observational computational bioinformatics analysis.

Materials and Methods:
Gene expression profiles for PCOS (GSE199225), EC (GSE215413) and OC (GSE174670) were obtained from the Gene Expression Omnibus database. Hub genes were identified through functional enrichment analysis and protein–protein interaction. Drug identification analyses were employed to find drugs targeting the hub genes.

Results:
Key hub genes linking PCOS and EC includes RECQL4, RAD54L, ATR, CHTF18, WDHD1, CDT1, PLK1, PKMYT1, RAD18 and RPL3; for PCOS and OC, they include HMOX1, TXNRD1, NQO1, GCLC, GSTP1, PRDX1, SOD1, GPX3, BOP1 and BYSL. Gene Ontology analysis revealed DNA metabolic process in PCOS and EC, while in PCOS and OC, it identified the removal of superoxide radicals. Kyoto Encyclopaedia of Genes and Genomes pathway analysis highlighted cell cycle in PCOS and EC and hepatocellular carcinoma in PCOS and OC. Potential drugs for PCOS and EC include quercetin, calcitriol and testosterone; for PCOS and OC, eugenol and 1-chloro-2,4-dinitrobenzene are identified.

Conclusion:
These findings offer insights into potential therapeutic targets and pathways linking PCOS with EC and OC, enhancing our understanding of the molecular mechanisms involved in these associations.
Assessment of Malaria Pharmacotherapeutic Outcomes in Children under 12 Years of Age among Three Health-care Facilities, Bayelsa, Nigeria
Authors: Charles Ronari O. , Bunu Samuel J. , Charles Oyintari , Orumwense Daniel O. 
Published: June 2024

Abstract

Background:
Malaria is Nigeria’s biggest public health problem, accounting for around 30% of all fatalities among children under 5 years, 25% of infant deaths, and 11% of maternal mortality.

Aims and Objectives:
The study aimed to identify the outcomes of malaria therapy in children under 12 who were admitted and managed at three health facilities in Bayelsa State, Nigeria, and if the treatment pattern adhered to standard guidelines.

Materials and Methods:
A detailed retrospective survey was designed, and a data collection instrument was utilized to obtain clinical, medical, and medication histories for children from the selected health facilities between January 2019 and June 2020. The survey collected data from 1312 children. The data were analyzed using a Chi-square test in SPSS version 23.0 and Microsoft Excel 2013.

Results:
From the data obtained, only 37.73% of the 1312 participants underwent a malaria parasite (MP) test. The most common diagnosis made at the Primary HealthCare Center (PHC) was acute/uncomplicated malaria (43.0%), followed by diarrhea (21.3%), and gastroenteritis (GET) with upper respiratory tract infection (15.7%). The most common diagnoses for Secondary HealthCare Center (SEC) and Federal/Tertiary HealthCare Center (FHI) were malaria with GET (22.5%) and severe malaria with meningitis (18.1%). The majority of patients were effectively handled and discharged, FHI (73.0%), SEC (91.1%), and PHC (94.0%). Other notable outcomes included patients’ task capacity and a temperature decreased to normal (TDN).

Conclusion:
There was a significant correlation between demographic data and treatment outcomes (P < 0.05). Although the three health facilities provided competent patient management along with appropriate prescription trends for malaria and comorbidities, there was a low proportion of patients who received an MP test, particularly at the FHI.
Prevalence of Xerostomia and Hyposalivation Among Individuals Attending Oral Cancer Screening in Thailand: A Cross-Sectional Study
Authors: Ekkert Sutthipoach , Deeiam Krongkan , Klongnoi Boworn , Sresumatchai Vanvisa , Pimolbutr Kununya , Khovidhunkit Siribang-on Piboonniyom 
Published: June 2024

Abstract

Aim:
It has been speculated that the prevalence of xerostomia and hyposalivation might be higher among individuals attending oral cancer screening than among members of the general population. Therefore, this study investigated the prevalence of these conditions and their associated factors among individuals taking part in oral cancer screening and residing in the northeastern provinces of Thailand.

Materials and Methods:
This cross-sectional study recruited convenient individuals aged ≥40 years with at least one oral cancer risk factor. In total, 561 participants were included. Demographic characteristics and relevant oral cancer risk factors were recorded. A questionnaire comprising five items was used to assess xerostomia. Participants were then categorized into two groups based on the absence or presence of xerostomia. Subsequently, the stimulated salivary flow rate was assessed using the spitting technique to identify hyposalivation. Participants were then separated into two groups depending on the absence or presence of hyposalivation. Univariate and multivariate logistic regression analyses were then performed to identify factors associated with xerostomia or hyposalivation.

Results:
The mean age of participants was 65.62 ± 9.70 years, and approximately 60% of participants were post-menopausal women. The prevalence of xerostomia was 43.85%, and the prevalence of hyposalivation was 61.50%. It was revealed that age ≥65 years (odds ratio [OR] = 1.57, P = 0.02) and burning sensation in the mouth (OR = 5.36, P < 0.001) were strongly associated with xerostomia. Female participants were more likely to exhibit hyposalivation (OR = 2.38, P = 0.001). Oral cancer risk factors were not associated with xerostomia or hyposalivation.

Conclusions:
In this study, age ≥65 years and burning sensation were identified as risk factors for xerostomia, whereas female sex was a risk factor for hyposalivation. Dentists should be aware of both conditions. Various interventions to alleviate dry mouth symptoms might be useful for individuals with these risk factors.
A Bibliometric Analysis of the Top 100 Cited Articles in Regenerative Periodontics Surgery: Insights and Trends
Authors: Alqahtani Hussam M. , Haq Ikram UI. , Alrubayan Mohammed , Alammari Faisal , Alotaibi Fahad , Al Khammash Abdalrahman 
Published: June 2024

Abstract

Aim:
The aim of this study was to identify and appraise the bibliometric properties of top 100 most-cited articles on regenerative periodontics surgery (RPS).

Materials and Methods:
The bibliometric research technique was conducted using a dataset comprising the 100 highly cited articles obtained from Elsevier’s Scopus database on RPS. Information regarding the growth of articles by year, number of citations, citations per year, study design, study field, modalities, journals, authors, and countries were extracted for each article. Microsoft Excel (v.16) was utilized for data evaluation and tabulation. These articles on RPS were published over a span of 45 years, from 1975 to 2019, with citation metrics ranging from 144 to 820. Out of the 422 participating authors, 82% contributed to a single article.

Results:
The 100 most cited articles on RPS were published in 45 years from 1975 to 2019 and number of citations ranged from 144 to 820. Out of the 422 participating authors, 82% contributed in a single article.. The study design with the highest number of cited articles was laboratory/animal studies. Others/not specified was the preferred modality, followed by infrabony modality. The Journal of Periodontology published about one-fourth of the articles, with W. V. Giannobile emerging as the most productive author. Among the 100 most-cited articles on RPS, authors from 25 different countries contributed, with the United States producing half of the articles (n = 51). Bibliometric investigation revealed that the most cited papers published before 2000 had higher citation counts due to their longer period of exposure. The ratio of authors per article increased after the year 2000.

Conclusions:
Infrabony emerges as a trending topic in RPS, with laboratory/animal studies, clinical trials, and literature reviews being the most frequently employed study designs.
A protocol of a systematic review and meta-analysis on the prevalence of mental health disorders among older adults and synthesis of community-based interventions among them in low- and middle-income countries
Authors: Das Devi , Khasnobis Madhurima , Dutta Susmita , Hoda Suchismita , Pal Arkaprovo , Sundström Christopher , Kraepelien Martin , Kandasamy Arun , Mehta Swati , Dahiya Neha , Saha Indranil , Saha Asim , Chakrabarti Amit 
Published: June 2024

Background:
Older adults of low- and middle-income countries (LMICs) have a higher prevalence of mental health disorders compared to high-income countries, which can be attributed to a combination of social factors (such as isolation and loss of spouse), declining physical well-being, and the cumulative impact of life stressors, all of which contribute to an increased vulnerability in mental health.

Objectives:
The objective of this study was to determine the pooled prevalence of mental health disorders among older adults in LMICs and to identify community-based mental health intervention measures to tackle mental health problems in LMICs.

Methods:
Articles will be retrieved from databases such as PubMed, Scopus, and Cochrane Central using MeSH terms, keywords, and text words for each concept. Preprint search servers (MedRx, Cogprints, IndiaRxiv, medRxiv, and SSRN) will also be accessed. Data analysis will be conducted as per guidelines provided in the Handbook of Cochrane Systematic Review. RevMan version 5.4 software will be used for pooled analysis. Expected outcome: This systematic review will be able to identify the pooled prevalence of mental health among older adults and will also identify the evidence-based mental health intervention measures in community settings among older adults of LMICs.