bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pectus Excavatum: Uncommon Electrical Abnormalities Caused by Extrinsic Right Ventricular Compression
Authors: CHAN WAH HAK YEE‐SEN , LIM YEONG‐PHANG , LIEW REGINALD , HSU LI‐FERN 
Published: December 2013

Pectus ExcavatumWe report a case of pectus excavatum associated with ventricular tachycardia provoked by exercise in a 19‐year‐old man. Although this chest deformity has been associated with supraventricular dysrhythmias, documented ventricular tachycardia has only been reported once. Our patient's ventricular dysrhythmia was treated by surgical correction of his pectus excavatum only, and at 3 years follow‐up he has had no recurrence of his ventricular tachycardia.
Progression of attachment loss is strongly associated with presence of the JP2 genotype of Aggregatibacter actinomycetemcomitans: a prospective cohort study of a young adolescent population
Authors: Höglund Åberg Carola , Kwamin Francis , Claesson Rolf , Dahlén Gunnar , Johansson Anders , Haubek Dorte 
Published: December 2013

AbstractAimTo assess the progression of attachment loss (AL) during a 2‐year period according to the presence of JP2 and non‐JP2 genotypes of Aggregatibacter actinomycetemcomitans in a Ghanaian adolescent population.MethodsA total of 500 adolescents (mean age 13.2 years, SD ± 1.5) were enrolled in the study. After 2 years, 397 (79.4%) returned for a periodontal re‐examination, including the measurement of AL. The carrier status of the JP2 and non‐JP2 genotypes of A. actinomycetemcomitans was evaluated in a baseline examination 2 years earlier.ResultsIndividuals who carried the JP2 genotype of A. actinomycetemcomitans had a significantly increased risk [relative risk (RR) = 7.3] of developing AL ≥ 3 mm. The mean AL at the follow‐up and the mean 2‐year progression of AL were significantly higher in the JP2 genotype‐positive group (n = 38) compared with the group positive for the non‐JP2 genotypes of A. actinomycetemcomitans (n = 169), and the group of A. actinomycetemcomitans‐negative individuals (n = 190). The JP2 genotype was strongly associated with the progression of AL ≥ 3 mm (OR = 14.3). The non‐JP2 genotypes of A. actinomycetemcomitans were also, however, less pronounced, associated with the progression of AL ≥ 3 mm (OR = 3.4).ConclusionThe JP2 genotype of A. actinomycetemcomitans is strongly associated with the progression of AL.
Clinical evaluation of coronally advanced flap with or without acellular dermal matrix graft on complete defect coverage for the treatment of multiple gingival recessions with thin tissue biotype
Authors: Ahmedbeyli Cavid , İpçi Şebnem Dirikan , Cakar Gokser , Kuru Bahar E. , Yılmaz Selçuk 
Published: December 2013

AbstractAimThe objective of this study was to compare acellular dermal matrix graft (ADM) combination with coronally advanced flap (CAF) on complete defect coverage, aesthetics and patient satisfaction with CAF alone for multiple recessions with gingival thickness (GT) <0.8 mm.Materials and MethodsForty‐eight Miller Class I multiple recessions ≥3 mm were divided into test (CAF + ADM) and control (CAF) groups. At baseline and 12 months, recession height (RH), keratinized tissue height (KT), GT, mean and complete defect coverage were evaluated. Patient satisfaction, root coverage aesthetic score (RES) and the correlation between GT and defect coverage were also assessed.ResultsBaseline RH in CAF + ADM and CAF groups was 3.25 ± 0.34 mm and 3.21 ± 0.26 mm, respectively. Mean and complete defect coverage were 94.84% and 83.33% in test group, 74.99% and 50.00% in control group, respectively. Inter‐group differences were found to be statistically significant for RH reduction, attachment gain, KT and GT increase, mean defect coverage and RES in favour of test group (p < 0.05). There was a significant positive correlation between GT and mean defect coverage (p < 0.05).ConclusionCoronally advanced flap in association with ADM can be proposed as a valid approach for the treatment of multiple recessions with thin tissue biotype.
Risk factors for the progression of periodontal attachment loss: a 5‐year population‐based study in South Brazil
Authors: Haas Alex Nogueira , Wagner Marcius Comparsi , Oppermann Rui Vicente , Rösing Cassiano Kuchenbecker , Albandar Jasim M. , Susin Cristiano 
Published: December 2013

AbstractAimTo assess sociodemographic and behavioural risk factors for periodontal attachment loss (PAL) progression after 5 years in an urban sample from south Brazil.MethodsAt baseline, 1586 subjects, 14 years and older, were derived using a multistage probabilistic sample strategy. At follow‐up, 653 of 755 subjects had ≥6 teeth and were included in this analysis. A modified multiple Poisson regression was used to calculate adjusted relative risks (RR) and 95% confidence intervals (CI).ResultsOverall, 247 (37.8%) subjects exhibited PAL progression ≥3 mm in ≥4 teeth. Subjects older than 30 years had approximately two times higher risk of having PAL progression than younger subjects. Subjects with low education had 53% higher risk (RR = 1.53; 95% CI:1.06–2.22) of PAL progression compared to those with high education. A significant interaction between gender and smoking was observed. Among never‐smokers, males were 33% more likely (RR = 1.33; 95% CI:1.06–1.66) to experience PAL progression than females. Among smokers, there was 8% increased risk of PAL progression (RR = 1.08; 95% CI:1.01–1.14) for males and 21% (RR = 1.21; 95% CI:1.11–1.33) for females per 10 packyears. Skin colour, socioeconomy, dental care and diabetes were not significantly associated with PAL progression after statistical adjustment.ConclusionSociodemographic factors and smoking are independent risk factors for PAL progression in this Brazilian population.
Culturing chelifers (Pseudoscorpions) that consume Varroa mites
Authors: Read S. , Howlett B. G. , Donovan B. J. , Nelson W. R. , van Toor R. F. 
Published: December 2013

AbstractChelifers (Pseudoscorpions) are generalist predators of small prey such as mites. Their occasional presence in honeybee hives suggests potential to exploit them as part of a management programme against Varroa mites (Varroa destructor), a significant pest of honeybees. Two species of native New Zealand chelifers Nesochernes gracilis and Heterochernes novaezealandiae, shown to consume Varroa mites, were collected from commercial nucleus hives or in litter surrounding the hives. Methods for mass‐rearing the chelifers were developed to provide specimens for research and introduction into beehives for biological control of Varroa. Cultures were fed aphids and fruit fly larvae in vented containers containing sand and bark. N. gracilis was maintained at 14°C, 18°C, and 22°C. At 18°C, 1423 nymphs were reared from 140 N. gracilis adults, with 84.8% of all nymphs produced at this temperature. H. novaezealandiae was maintained at 18°C and 22°C, with 5 nymphs raised from 12 adults at 18°C and none at the higher temperature.
Resting sites, edge effects and dispersion of a polyphagous Bactrocera fruit fly within crops of different architecture
Authors: Balagawi S. , Jackson K. , Clarke A. R. 
Published: December 2013

AbstractThe spot or strip application of poisoned protein bait is a lure‐and‐kill technique used for the management of fruit flies. Knowledge of where flies occur in the crop environment is an important part of maximizing the efficacy of this tool. Bactrocera tryoni is a polyphagous pest of horticulture for which very little is known about its distribution within crops. With particular reference to edge effects, we monitored the abundance of B. tryoni in two crops of different architecture; strawberry and apple. In strawberries, we found more flies on the crop edge early in the fruiting season, which lessened gradually and eventually disappeared as the season progressed. In apple orchards, no such edge effect was observed and flies were found equally throughout the orchard. We postulated these differences may be due to differences in crop height (high vs. short) and/or crop canopy architecture (opened and branched in apple, dense and closed in strawberry). In a field cage trial, we tested these predictions using artificial plants of different height and canopy condition. Height and canopy structure type had no significant effects on fly oviposition and protein feeding, but the ‘apple’ type canopy significantly influenced resting. We thus postulate that there was an edge effect in strawberry because the crop was not providing resting sites and flies were doing so in vegetation around the field margins. The finding that B. tryoni shows different resting site preferences based on plant architecture offers the potential for strategic manipulation of the fly through specific border or inter‐row plantings.
Iron‐Chelating Properties of Melanoidins and Inducing Effect of Pulsed Electric Field
Authors: Wang Zhonghe , Wang Jun , Guo Shoujun , Xue Xiaoli , Yu Shujuan 
Published: December 2013

AbstractIron‐chelating properties of melanoidins, derived from glucose–glycine model system, were firstly investigated, and then melanoidin‐iron solutions were subjected to pulsed electric field (PEF) treatment at electric field strength of 0 to 80 kV/cm, respectively. Iron‐chelating ability of melanoidins decreased with increasing ferrous concentrations and reached the saturation state to bind 2.36 mg iron (II) per gram of melanoidin. At pH 3.0, the iron‐chelating ability of melanoidins was higher, partly due to isoelectric precipitation. The PEF treatment significantly increased the chelating ability of melanoidins toward Fe (II) at 20 and 80 kV/cm (P < 0.05 versus the control group), and the increased values were achieved 20.0 and 21.4%, respectively. The enhancing effects of PEF treatment on iron‐chelating ability of melanoidins were probably attributed to preservation of more negative charge in melanoidins molecule induced by PEF to facilitate the binding of more cationic species, or acceleration of Maillard reaction at high intensity of PEF.Practical ApplicationsMelanoidins‐iron (II) solutions (pH 5.0) were subjected to PEF treatment at different electric intensities of 20–80 kV/cm. Results presented in this article should find their practical applications in the field of food industries. They will enhance the iron‐chelating abilities of melanoidins in shorter time and at lower temperature.
How reliable are design flood estimates in the UK?
Authors: Kjeldsen T.R. 
Published: December 2013

AbstractDesign flood estimates in the UK are routinely obtained by using the improved Flood Estimation Handbook (FEH) statistical procedure. This paper presents a practical framework for assessing the uncertainty associated with estimates of the index flood (QMED) obtained for a range of commonly encountered problems: the gauged, the ungauged and the sparsely gauged catchment. An assessment is presented of the uncertainty of design flood estimates when estimated at ungauged catchments for a range of return periods. The results show that the inclusion of data from nearby gauged catchments increases the reliability of the estimates when compared to an automated application of the improved FEH methods relying on catchment descriptors only.
Genome‐wide identification and expression analyses of cytochrome P450 genes in mulberry (Morus notabilis)
Authors: Ma Bi , Luo Yiwei , Jia Ling , Qi Xiwu , Zeng Qiwei , Xiang Zhonghuai , He Ningjia 
Published: December 2013

AbstractCytochrome P450s play critical roles in the biosynthesis of physiologically important compounds in plants. These compounds often act as defense toxins to prevent herbivory. In the present study, a total of 174 P450 genes of mulberry (Morus notabilis C.K.Schn) were identified based on bioinformatics analyses. These mulberry P450 genes were divided into nine clans and 47 families and were found to be expressed in a tissue‐preferential manner. These genes were compared to the P450 genes in Arabidopsis thaliana. Families CYP80, CYP92, CYP728, CYP733, CYP736, and CYP749 were found to exist in mulberry, and they may play important roles in the biosynthesis of mulberry secondary metabolites. Analyses of the functional and metabolic pathways of these genes indicated that mulberry P450 genes may participate in the metabolism of lipids, other secondary metabolites, xenobiotics, amino acids, cofactors, vitamins, terpenoids, and polyketides. These results provide a foundation for understanding of the structures and biological functions of mulberry P450 genes.
Pigmented concealing powders for the hair loss patient
Authors: Cossman Jack P , Ladizinski Barry , Lee Kachiu C 
Published: December 2013

SummaryPatients suffering from alopecia may experience low self‐esteem, low self‐image, and other psychological consequences. While medical and surgical options for treating hair loss exist, these may be prohibitively expensive or have an unpredictable outcome. In lieu of or in addition to therapeutic approaches, cosmetic options have long been an approach to hair loss. However, patients and clinicians alike often regard cosmetic options to be limited to hairstyling and hairpieces, unaware that newer options, namely pigmented concealing powders, may offer a more practical and seemingly natural camouflage. This article introduces the clinician to concealing powders as a viable option for the hair loss patient.
Protective effects of skin permeable epidermal and fibroblast growth factor against ultraviolet‐induced skin damage and human skin wrinkles
Authors: An Jae Jin , Eum Won Sik , Kwon Hyuck Se , Koh Jae Sook , Lee Soo Yun , Baek Ji Hwoon , Cho Yong‐Jun , Kim Dae Won , Han Kyu Huyng , Park Jinseu , Jang Sang Ho , Choi Soo Young 
Published: December 2013

SummaryBackgroundEpidermal and fibroblast growth factor (EGF and FGF1) proteins play an important role in the regeneration and proliferation of skin cells. EGF and FGF1 have considerable potential as possible therapeutic or cosmetic agents for the treatment of skin damage including wrinkles.ObjectivesUsing protein transduction domains (PTD), we investigated whether PTD‐EGF and FGF1 transduced into skin cells and tissue. Transduced proteins showed protective effects in a UV‐induced skin damage model as well as against skin wrinkles.MethodsTransduced PTD‐EGF and FGF1 proteins were detected by immunofluorescence and immunohistochemistry. The effects of PTD‐EGF and FGF1 were examined by WST assay, Western blotting, immunohistochemistry, and skin wrinkle parameters.ResultsThe PTD‐EGF and FGF1 increased cell proliferation and collagen type 1 alpha 1 protein accumulation in skin tissue. Also, PTD‐EGF and FGF1 inhibited UV‐induced skin damage. Furthermore, topical application of PTD‐EGF and FGF1 contained ampoules which were considered to improve the wrinkle parameters of human skin.ConclusionThese results show that PTD‐EGF and FGF1 can be a potential therapeutic or cosmetic agent for skin damaged and injury including wrinkles and aging.
ALTERNATIVE WEIGHTING APPROACHES TO COMPUTING INDEXES OF ECONOMIC ACTIVITY
Authors: Lim G.C. , Nguyen Viet Hoang 
Published: December 2013

AbstractThis paper compares the weighting schemes in the traditional, principal component and dynamic factor approaches to summarizing information from a number of component variables. To facilitate the comparison, we propose a framework to discuss the approaches with respect to their implied loadings in a latent variable model. We also propose a way to transform the dynamic factor index into an analogous index which is a weighted average of the components. The framework shows the strengths and weakness of the alternative weighting schemes and the sense in which the dynamic factor approach has the advantage of capturing both the significance and the variability of the components.
The Role of Endovascular Treatment for Ruptured Distal Anterior Cerebral Artery Aneurysms: Comparison with Microsurgical Clipping
Authors: Park Keun Young , Kim Byung Moon , Lim Yong Cheol , Chung Joonho , Kim Dong Joon , Joo Jin Yang , Huh Seung Kon , Kim Dong Ik , Lee Kyu Chang , Lee Jae Whan 
Published: December 2013

ABSTRACTBACKGROUND AND PURPOSEThe purpose of this study was to compare clinical outcomes and treatment‐related complications between coiling and clipping for ruptured distal anterior cerebral artery (DACA) aneurysms.METHODSEighty‐four consecutive patients (M:F = 36:48; mean 53.8 years) with ruptured DACA aneurysms were treated by either clipping (n = 46, 54.8%) or coiling (n = 38, 45.2%). The clinical outcomes and procedure‐related complications were evaluated and compared between the two groups.RESULTSProcedure‐related complications tend to occur more frequently in the clipping (n = 6, 13.0%) than coiling group (n = 1, 2.6%) (P = .121). At discharge, 51 patients (60.7%) had favorable outcomes (Glasgow outcome scale [GOS], 4 or 5). There was no significant difference between the two groups in favorable outcome (63.2% vs. 58.7%; P = .677). Hunt and Hess (HH) grade (P < .001; 95% CI, 3.354‐29.609) and treatment modality (P = .044; 95% CI, 1.039‐16.325) were independent risk factors for poor outcome (GOS, 1‐3).CONCLUSIONSCoiling was more favorable to clipping in clinical outcomes and incidence of treatment‐related complications for ruptured DACA aneurysms.
A simplified method to screen for in-vivo performance of oral lipid formulations
Authors: Kilic Murat , Dressman Jennifer 
Published: December 2013

Abstract

Objectives
To develop a simplified in-vitro screening method for oral lipid-based formulations using intestinal biorelevant media including lipolysis, as an alternative to pH-stat lipolysis models.

Method
Fasting state simulated intestinal fluid version 2 (FaSSIF-V2) and early fed state simulated intestinal fluid (FeSSIF) were modified for use in a simplified lipolysis screening method. This screening method consists of the following steps: dispersion of the lipid formulation in biorelevant media; incubation of dispersions on an orbital shaker for 60 min at 37°C; ultracentrifugation of dispersions and drug assay of supernatants. This method was evaluated using four lipid-based formulations containing danazol, which had previously been assessed by in-vitro pH-stat lipolysis and compared in an in-vivo study in dogs.

Key findings
Biorelevant media were modified under consideration of both physiological and practical aspects, including adjustment of the pH to 6.5, the addition of calcium ions and the addition of 100 U/ml porcine pancreatin to enable lipolysis of a test formulation. Using a modified FaSSIF-V2, the same rank order in performance of four danazol formulations as previously observed in a pH-stat model was observed, and these results also reflected the in-vivo study results. The results in modified early FeSSIF suggested that there would be a change in the rank order of formulation performance in the fed state compared with the fasted state. By comparing the formulation behaviour in the presence and absence of pancreatin, it was concluded that dispersion is more important than lipolysis for precipitation from the formulation in the fasted state, but that lipolysis is predicted to increase in relevance in the fed state.

Conclusion
The new, simplified method for lipolysis enables a more efficient screening for the in-vivo performance of lipid formulations in the fasted state and enables a prediction of formulation behaviour in both the fed and fasted states. An additional advantage of the method is that the relative influence of lipolysis and dispersion on drug release can be directly compared.
Characteristics of Jordanian depressed pregnant women: a comparison study
Authors: Abuidhail J. , Abujilban S 
Published: December 2013

Accessible summary
Jordanian women reported double the rates of antenatal depression in comparison with developed countries. Further, no studies have been conducted here in Jordan that compares sociodemographic characteristics of women who have antenatal depression symptoms and women who do not have such symptoms.
The results of this study revealed that Jordanian pregnant women who were smokers, less educated and those with high‐parity pregnancy had a high tendency towards antenatal depressive symptoms.
Nurses and midwives need to work together to prevent and predict antenatal depression. They need to identify the women who are suffering from it and effectively help them to protect the next generation from its negative effects.
AbstractThe objective of this study is to investigate the differences between Jordanian depressed women and non‐depressed women in terms of their sociodemographic characteristics during their pregnancy. A convenience sample of 218 Jordanian pregnant women in their third trimester was selected for this study from three major Governorates in Jordan (Amman, Irbid and Zarqa), and the antenatal clinics of teaching hospitals (Jordan University Hospital and King Abdullah University Hospital) were accessed to collect the data. A demographical sheet and the Edinburgh Postnatal Depression Scale (EPDS) were used to collect data. There was a significant difference in EPDS scores between smokers and non‐smokers, primiparous and multiparous women, and also between women with secondary or lower education and those with diploma or higher education. Higher EPDS scores were classified as a ≥13 and lower EPDS scores as <13. However, there were no significant differences in the age, income and sleeping hours for women with higher EPDS scores compared with those with lower EPDS scores. This study showed that there are differences between pregnant women who had depression symptoms and pregnant women who did not have depression symptoms in relation to some sociodemographic variables (smoking status, education level and parity).
Brewer's yeast and sugarcane yeast as protein sources for dogs
Authors: Martins M. S. , Sakomura N. K. , Souza D. F. , Filho F. O. R. , Gomes M. O. S. , Vasconcellos R. S. , Carciofi A. C. 
Published: December 2013

SummaryBrewer's yeast (BY), autolysed sugarcane yeast (ASCY) and integral sugar cane yeast (ISCY) were studied in two experiments as ingredients for dog diets. In the first experiment, 28 dogs were randomly assigned to four diets; one reference diet and three test diets containing 15% of BY, ASCY or ISCY and 85% of the reference diet (as‐fed basis). The digestibilities of the yeasts were calculated by the substitution method. In the second experiment, 35 dogs were randomized to five diets with similar chemical composition but different levels of sugarcane yeast inclusion (0%, 7.5% ASCY, 15% ASCY, 7.5% ISCY and 15% ISCY). In both experiments, the coefficient of total tract apparent digestibility (CTTAD) of nutrients was determined through total collection of faeces. During experiment, two additional analyses of food palatability, nitrogen balance and urea postprandial responses were performed. The data were submitted to analysis of variance, and the means were compared by orthogonal or polynomial contrasts or Tukey's test (p < 0.05). In experiment 1, CTTAD of protein was lower for both sugarcane yeasts than for BY (p = 0.012), as was metabolizable energy content (p = 0.025). In experiment 2, a linear reduction in energy digestibility with ASCY inclusion (p = 0.05) was verified. Furthermore, faecal score and DM content were reduced with ISCY inclusion (p < 0.003). No effect of yeast inclusion on nitrogen balance or postprandial urea response was found. Also, the inclusion of 7.5% of ASCY or ISCY increased diet palatability (p < 0.01). Yeasts present adequate digestibility by dogs, but its effect on faecal formation needs to be considered. No clear advantage for the use of ASCY over ISCY was found. In conclusion, we find that sugarcane yeast is suitable for inclusion in dog food and can enhance the overall palatability of the diet.