bluuebunny/crossref_metadata_2025_split huggingface dataset:
The relationships of personality organization, mental illness attitudes and perspectives toward psychotherapy: The mediating role of emotional self‐disclosure
Authors: Rahimian Bougar Mojtaba , Khavasi Sara , Khodarahimi Siamak , Mazraeh Nasrollah , Merati Alireza , Hesam Maeda , Alavi Pantea Sadat 
Published: July 2024

AbstractThis study investigated the relationships between personality organization, Mental Illness Attitude (MIA), and Perspectives Toward Psychotherapy (PTP) with regard to the mediating role of Emotional Self‐Disclosure (ESD) by utilizing structural equation modeling (SEM). A sample of 266 outpatients with mental health disorders was selected using a purposive sampling method. Data collection involved the use of the Inventory of Personality Organization, The Illness Attitudes Scale, Emotional Self‐Disclosure Scale, and Attitudes Toward Seeking Professional Psychological Help‐The10‐item (ATSPPH‐SF). The results revealed that personality organization, MIA, and ESD have significant associations with PTP. Also, MIA has a positive indirect relationship with PTP through ESD as a mediator, while personality organization negatively correlated to PTP through ESD. Personality organization, MIA, and ESD collectively accounted for 72.8% of the variance in PTP. Findings demonstrated an adequately fitting model about the direct and indirect associations of personality organization and MIA with PTP about the mediating role of ESD. This model has implications for psychotherapeutic and community‐based initiatives in individuals with mental health disorders.
CD4+CD8αlow T Cell Clonal Expansion Dependent on Costimulation in Patients With Rheumatoid Arthritis
Authors: Beck Felix , Nguyen Phuong , Hoffmann Anne , Loyal Lucie , Thiel Andreas , Melzer Marc , Apel Hannah , Pierer Matthias , Krasselt Marco , Seifert Olga , Glimm Anne‐Marie , Hagemann Tobias , Rothe Kathrin , Wagner Ulf 
Published: July 2024

ObjectiveCD4+CD8+ T cells are increased in patients with rheumatoid arthritis (RA). They are not only associated with joint erosions in established disease but are also present in the preclinical stages of RA. This study aims to further investigate their expansion in the context of T cell clonality in patients with RA, as well as their responsiveness to T cell–targeted treatment.MethodsSingle‐cell RNA (scRNA) and single‐cell T cell receptor (TCR) sequencing data were used to determine coreceptor expression and TCR sequences to assess the clonality of CD4+CD8+ T cells in patients with RA (n = 3) and healthy controls (n = 2). Peripheral CD4+CD8+ T cells and their subpopulations were measured in patients with RA (n = 53), patients with psoriatic arthritis (PsA; n = 52), and healthy donors (n = 50) using flow cytometry. In addition, changes in CD4+CD8+ T cell frequency were prospectively observed in patients with RA receiving therapy with abatacept for 12 weeks.ResultsWe observed an increase of CD4+ T cells expressing CD8α in patients with RA, both in comparison to patients with PsA and healthy controls. Clonality analysis revealed that these CD4+CD8αlow T cells are part of large T cell clones, which cluster separately from CD4+CD8− T cell clones in the scRNA sequencing (scRNA‐seq) gene expression analysis. Treatment with abatacept significantly reduced the frequency of peripheral CD4+CD8αlow T cells, and this was linked to reduction in disease activity.ConclusionIn patients with RA, clonal expansion of CD4+ T cell culminates in the emergence of peripheral CD4+CD8αlow T cells, which are associated with disease activity and diminished upon abatacept treatment and could contribute to disease pathogenesis.image
Moderate altitude as a risk factor for isolated congenital malformations. Results from a case–control multicenter–multiregional study
Authors: Ibarra‐Ibarra Blanca Rebeca , Luna‐Muñoz Leonora , Mutchinick Osvaldo M. , Arteaga‐Vázquez Jazmín 
Published: July 2024

AbstractBackgroundLiving in high‐altitude regions has been associated with a higher prevalence of some birth defects. Moderate altitudes (1500–2500 m) have been associated with some congenital heart diseases and low birth weight. However, no studies have been conducted for other isolated congenital malformations.ObjectivesTo estimate the prevalence at birth of isolated congenital malformations in low and moderate altitudes and to determine if moderate altitudes are a risk factor, such as high altitudes, for isolated congenital malformations adjusted for other factors.MethodsThe study consisted of a case–control multicenter‐multiregional study of 13 isolated congenital malformations. Cases included live births with isolated congenital malformations and controls at low (10–1433 m) and moderate altitudes (1511–2426 m) from a Mexican registry from January 1978 to December 2019. Prevalence per 10,000 (95% CI) per altitude group was estimated. We performed unadjusted and adjusted logistic regression models (adjusted for maternal age, parity, malformed relatives, socioeconomic level, and maternal diabetes) for each isolated congenital malformation.ResultsHydrocephaly and microtia had a higher at‐birth prevalence, and spina bifida, preauricular tag, and gastroschisis showed a lower at‐birth prevalence in moderate altitudes. Moderate altitudes were a risk factor for hydrocephaly (aOR 1.39), microtia (aOR 1.60), cleft‐lip‐palate (aOR 1.27), and polydactyly (aOR 1.32) and a protective effect for spina bifida (aOR 0.87) compared with low altitudes.ConclusionsOur findings provide evidence that moderate altitudes as higher altitudes are an associated risk or protective factor to some isolated congenital malformations, suggesting a possible gradient effect.
Childhood B cell leukemia: Intercepting the paths to progression
Authors: Cobaleda Cesar , Vicente‐Dueñas Carolina , Nichols Kim E. , Sanchez‐Garcia Isidro 
Published: July 2024

AbstractB‐cell Acute Lymphoblastic Leukemia (B‐ALL) is the most common pediatric cancer, arising most often in children aged 2–5 years. This distinctive age distribution hints at an association between B‐ALL development and disrupted immune system function during a susceptible period during childhood, possibly triggered by early exposure to infection. While cure rates for childhood B‐ALL surpass 90% in high‐income nations, survivors suffer from diminished quality of life due to the side effects of treatment. Consequently, understanding the origins and evolution of B‐ALL, and how to prevent this prevalent childhood cancer, is paramount to alleviate this substantial health burden. This article provides an overview of our current understanding of the etiology of childhood B‐ALL and explores how this knowledge can inform preventive strategies.
Assessment of luminescent copper nanomaterials as anti‐germs, anti‐proliferation efficiencies using green nano‐strategy
Authors: Elavarasan Vidhya , Vijayakumar Subramaniyan , Aldawood Saad , Thangaswamy Selvankumar , Prathipkumar Subramaniyan 
Published: July 2024

AbstractFor the first time, we suggest using leaf extract from Ocimum americanum as the economically viable bio‐fabrication of copper nanomaterials. The residuals of leaf extract bio‐capping provide the stability of the nanomaterials in‐situ. UV–Vis and XRD confirmed the formation, with the UV–Vis spectrum of Cu‐NMs revealing a surface plasmon resonance characteristic peak at 350 nm. FT‐IR analysis was employed to examine the functional groups. FE‐SEM with EDX was used to assess the morphology and carry out an elemental analysis of the nanomaterials. Diffusion and MTT assays were used to study the antimicrobial and anticancer activities. The synthesized copper nanomaterials exhibited in‐vitro cytotoxicity against human skin cancer (A431) cell lines. Green nanomaterial was examined against the methylene blue dye, photodegradation was reduced by up to 90.6% within 50 minutes. The copper nanomaterials synthesized in our study exhibit promising applications in biomedicine and environmental pollution research.
Preparation of liquid silicon‐based carbon dots and application for luminescent solar concentrators
Authors: Lu Tianshun , Xu Shuhong , Gao Lianping 
Published: July 2024

AbstractLiquid silicon‐based carbon dots (CDs) with a photoluminescence quantum yield (PLQY) of 50% were prepared using N‐[3‐(trimethoxysilyl)propyl]ethylenediamine (DAMO), citric acid, and n‐butylamine as raw materials. Firstly, the optimized characters have been determined, namely, the optimal DAMO, citric acid, and n‐butylamine addition amounts of 1 mL, 0.9 g, and 1 mL, a reaction time of 3 h, and a reaction temperature of 160°C. Further research has confirmed that the increase in fluorescence intensity of CDs is mainly due to the introduction of DAMO, in which the two amino groups in DAMO play a major role. In addition, the Si‐O‐Si group generated by the hydrolysis of siloxane groups is connected to the surface of the CDs and forms a core–shell structure, which modifies the defects on the surface and enhances the fluorescence intensity of the CDs. Finally, luminescent solar concentrators (LSCs) based on liquid silicon‐based CDs were assembled by spin coating. The obtained device has a transparency of up to 80% and an optical efficiency of 2.4%.
Cognitive functioning in adult psychiatric patients with and without attention‐deficit/hyperactivity disorder
Authors: Eberhard D. , Gillberg C. , Billstedt E. 
Published: July 2024

AbstractIntroductionStudies of cognitive functioning in patients with attention‐deficit/hyperactivity disorder (ADHD) have often used healthy comparison groups. The present study examines cognitive profiles, including general intellectual and executive functions, in a young adult psychiatric outpatient clientele with ADHD and evaluates whether their cognitive profiles can help differentiate them from patients with non‐ADHD‐associated psychiatric disorders.MethodsThe study group comprised 141 young adult psychiatric patients (age range 18–25 years) of whom 78 had ADHD. Comprehensive neuropsychological assessment included the Wechsler Adult Intelligence Scale, 4th version and subtests from Delis–Kaplan Executive Function System. Clinical psychiatric assessments and diagnostic evaluation were performed.ResultsThe ADHD group (including all subtypes) had significantly lower verbal comprehension and full‐scale intelligence quotient than the non‐ADHD group. Tests measuring working memory or executive function did not separate those with and without ADHD.ConclusionThe results of our study suggest that, except for the need to establish overall cognitive performance level, the clinical implication of testing is small if the purpose is to “rule out” an ADHD diagnosis.
Mechanism of green and knowledge process toward minimizing innovation risks: A direct and configuration approach
Authors: Alam Sajjad , Zhang Jianhua , Khan Naveed , Dandan Wen 
Published: July 2024

AbstractDue to a significant reduction in the availability and standard of natural resources, numerous firms are claiming to implement environmentally sustainable practices. This research constructs and validates green variables within the knowledge management (KM) process, drawing on resource‐based views (RBV) and organizational learning theory. It aims to explain how manufacturing firms minimize innovation risk. The author followed a combined methodology of Smart partial least squares structural equation modeling (PLS‐SEM) and fuzzy set qualitative comparative analysis (fsQCA). Primary response data were collected from industry experts and literature studies to develop items for the knowledge aptitude model to decrease innovation risk (KMIR). The mixed variables of the KM and green process were validated through the fsQCA technique. The outcome of PLS‐SEM showed a positive connection between certain green variables to minimize innovation risk. fsQCA examines the combined approach of green implementation and KM practice; the finding indicated significant connections between green variables and the KM process to KMIR. This study can be measured as innovative in the KMIR field, as it has validated and developed its constructs based on primary data. It can help scholars and industry experts acquire a head start in the KMIR field, and this mechanism will assist with the investigation of the green variables and knowledge domain, providing an outline for future studies.
Successful treatment of a complete Susac syndrome in a 16‐year‐old boy: A case report
Authors: Kashipazha Davood , Bahramy Mohammad Ali , Razaghi Mahshad , Rahimi Zeinab 
Published: July 2024

Key Clinical MessageWe reported a pediatric case of SuS with a complete diagnosis triad. Although the optimal treatment of SS is unclear, prompt diagnosis and treatment can result in almost a complete recovery.AbstractSusac's syndrome (SuS) is a rare, autoimmune disorder known as a typical triad of sensorineural hearing impairment, central nervous system involvement, and multiple branch retinal artery occlusions (BRAOs). It is usually misdiagnosed or underdiagnosed because its symptoms may vary at the presentation time. Diagnosis can be established based on neuroimaging, ophthalmic examination, and audiometry, which match the clinical symptoms. SuS is very limited and rare in childhood and can be easily misdiagnosed with multiple sclerosis or acute disseminated encephalomyelitis. We report a 16‐year‐old boy patient with a completed SuS triad including BRAO in fluorescent angiography (FA), mild to moderate sensory neural hearing loss (SNHL), “Snowball lesions,” and “pearl of string” signs in magnetic resonance imaging (MRI). Successful treatment was achieved with methylprednisolone, rituximab, azathioprine, cyclophosphamide, and plasmapheresis. SuS is a rare disorder, which rarely presents with a full triad and all the manifestations may not be present at the onset of the disease, leading to misdiagnosis or underdiagnosis. Our case is exceptional because he was in a pediatric age and presented with a complete triad of SuS which adds to the rarity of this disease. Although optimal treatment of SuS is unclear, our treatment regimen resulted in almost a complete recovery.
Successful treatment for an adult with bilateral posterior teeth crossbite by miniscrew‐assisted rapid palatal expansion: A case report
Authors: Fan Yuan , Li Yuanyuan , Fan Manlin , Lin Yanfang , Xu Jiarong , Li Zhihua , Luo Jun 
Published: July 2024

Key Clinical MessageSuccessful treatment by miniscrew‐assisted rapid expansion and clinical aligner therapy for an adult diagnosed with maxillary transverse deficiency (MTD) by clinical examinations and Yonsei transverse analysis.AbstractAdult orthodontic diagnosis and treatment with maxillary transverse deficiency (MTD) is challenging. Miniscrew‐assisted rapid palatal expansion (MARPE) is a fast and low‐risk method to expand the width of maxillary basal bone. This case report describes a 23‐year‐old female with mandible deviation and bilateral posterior teeth crossbite. She was diagnosed as MTD by the clinical examinations and Yonsei transverse analysis, and treated by the MARPE and clinical aligner therapy. After 26 months' treatment, cone‐beam computed tomography (CBCT) images showed that the width of maxillary basal bone increased by 3.8 mm, that of zygomatic arch and nasal bone increased by 1.0 and 1.9 mm, respectively, and the bilateral posterior teeth crossbite was corrected. Furthermore, the dental midline of lower arch was consistent with that of upper arch and face, the molars arrived Angle Class II and canines was Class I relationships, the profile was maintained, the facial asymmetry was improved. The results of seventeen‐month follow‐up showed that the effect of orthodontic treatment is very stable. This case report demonstrates that MARPE is the effective approach for patients with MTD and facial asymmetry, which provide the alternative for the treatment of similar cases.
Dual Electron Donating Metal‐Boron Reaction Center Boosts Electrocatalytic Urea Synthesis from N2 and CO2
Authors: Yodsin Nuttapon , Mano Poobodin , Takahashi Kaito , Namuangruk Supawadee 
Published: July 2024

AbstractUrea (NH2CONH2) production by electrosynthesis at mild conditions has been hampered due to the lack of systematic evaluation of pathways in effectively activating inert N2 and CO2 molecules and facilitating the formation of C−N bonds. In this work, we evaluated 16 transition metal (M) atoms anchored on carbon nitride nanosheet with boron (B) doping (M−B@C2N) for boosting urea production by theoretical calculations. All possible urea synthesis pathways, (i) CO2 pathway, (ii) OCOH pathway, (iii) CO pathway, and (iv) NCON pathway, were comparatively studied on Cu, Fe, Co, Ni−B@C2N. This systematic calculation identified that the first reduction of *N2 is the key step for urea synthesis. We found that the bond index of *N2 shows a strong correlation with ΔG*N2→*NNH, so they are promising descriptors for screening. Through the screening, we found that Nb‐ and Mo−B@C2N show a low limiting potential of −0.56 and −0.53 V. Although previous studies found that spin could promote C−C bond formation on M−B@C2N, we found that for C−N coupling, such effects by spin were only active for Nb−B@C2N. Combining boron and early transition metal atoms allows for neighboring reaction sites that simultaneously donate electrons to activate inert N2 and CO2 for efficient urea synthesis.
Ability of x‐ray computed tomography to resolve critical flaw size in laser‐based, paste stereolithography ceramic printing of alumina
Authors: Cramer Corson L. , Rossy Andrés Márquez , Dehoff Ryan R. , Nelson Andrew T. 
Published: July 2024

AbstractComplex alumina parts were printed using vat photopolymerization (VPP), which is a stereolithography‐based additive manufacturing (AM) technique used to shape ceramic preforms, or green parts. The critical flaw size was determined using classical fracture mechanics techniques. The strength and fracture toughness were measured and compared to flaws detected in x‐ray computed tomography (XCT or CT) distributions as well as the fracture surfaces. The strength was lower compared traditionally made alumina, and that is due to layering effects, slurry defects, and printing defects. The critical flaw size from fracture mechanics was 206 µm. XCT has high enough resolution to detect the critical flaw size and much smaller features, where the average flaw size observed in CT scans was around 80–100 µm. The fracture surfaces indicate that flaws causing failure are larger than that of the critical flaw size (∼300 µm), but fracture surfaces do not show definitive features compared to traditionally made ceramics. Since XCT can observe flaws smaller than the critical flaw size, this method can be used as a screening technique.
A Data‐Driven Approach for Enhanced CO2 Capture with Ruthenium Complexes
Authors: Liang Guangchao , Zhang Min 
Published: July 2024

AbstractTo attain carbon neutrality, significant efforts have been made to capture and utilize CO2. The homogeneous hydrogenation of CO2 catalyzed by transition metal complexes, particularly the ruthenium complexes, has demonstrated significant advantages and is regarded as a viable approach for practical application. Insertion of CO2 into the Ru−H bond, producing the Ru‐formate product, is the key step in the hydrogenation of CO2. In order to parameterize the catalytic activities in the CO2 insertion into the Ru−H bond, the concept of simplified mechanism‐based approach with data‐driven practice (SMADP) has been introduced in this paper. The results showed that the hydricity of the Ru−H complex (ΔGH‐) might serve as a single active descriptor in the process of CO2 insertion, and that a novel ruthenium complex in CO2 catalysis may not be easily obtained by mere modification of the auxiliary ligand at the ruthenium metal site.
Chemoselectivity Switch between Enantioselective [2,3]‐Wittig Rearrangement and Conia‐Ene‐Type Reactions of Propargyloxyoxindoles
Authors: Gao Yu‐Lin , Yang Yang , Wu Chen , Xie Ming‐Sheng , Guo Hai‐Ming 
Published: July 2024

AbstractDespite the existence of three competing reactions for propargyloxyoxindoles, we report a chemoselectivity switch between enantioselective propargyl [2,3]‐Wittig rearrangement and Conia‐ene‐type reactions, with suppression of the [1,2]‐Wittig‐type rearrangement. Using C1‐symmetric imidazolidine‐pyrroloimidazolone pyridine as the ligand and Ni(acac)2 as the Lewis acid, diverse 3‐hydroxy 3‐substituted oxindoles containing allenyl groups were obtained in up to 98 % yield and 99 % ee via asymmetric propargyl [2,3]‐Wittig rearrangement. In the presence of AgOTf‐Duanphos, chiral spiro dihydrofuran oxindoles were given in up to 98 % yield and 91 % ee through a Conia‐ene‐type reaction.
A mini‐review of intensified synthesis of 1st and 2nd generation biofuels in the presence of perovskite catalysts
Authors: Sai Bharadwaj Aryasomayajula Venkata Satya Lakshmi , Phillips Jason Joseph , Venkateshbabu Janani , Kammathanahalli Shivappa Gajendra , Venkatesh Archana , Gupta Navneet Kumar 
Published: July 2024

AbstractEnhancement of a sustainable environment through the choice of a selective catalyst with high activity, regeneration nature, and high stability is an important aspect to be focused on to achieve a high yield and maximum conversion of feedstock to biodiesel (1st generation biofuel), and also in the biomass valorization/pyrolysis (2nd generation biofuel synthesis). Depending on the nature of the catalyst and synthesis method adopted for biofuel production and biomass valorization, the variations in the process conditions, final yield, and conversion are varied accordingly. A prospective development and application of perovskite catalysts in the synthesis of 1st and 2nd generation biofuels using various process intensification strategies for the development of a clean and green environment is reviewed in this study. The synthesis of types of perovskite catalysts polycrystalline, nano‐sized, and powdered oxide are also discussed in this review. It is also concluded that, apart from other process parameters, molar ratio is one of the most influencing sensitive factors in the case of 1st generation biofuel synthesis, whereas during the production of 2nd generation biofuels, catalyst concentration and liquid–solid ratio are more significant process parameters that change based on the nature of the catalyst selected for the reaction.