bluuebunny/crossref_metadata_2025_split huggingface dataset:
Role of phosphatase activity of soluble epoxide hydrolase in regulating simvastatin-activated endothelial nitric oxide synthase
Authors: Hou Hsin-Han , Liao Yi-Jen , Hsiao Sheng-Huang , Shyue Song-Kun , Lee Tzong-Shyuan 
Published: August 2015

AbstractSoluble epoxide hydrolase (sEH) has C-terminal epoxide hydrolase and N-terminal lipid phosphatase activity. Its hydrolase activity is associated with endothelial nitric oxide synthase (eNOS) dysfunction. However, little is known about the role of sEH phosphatase in regulating eNOS activity. Simvastatin, a clinical lipid-lowering drug, also has a pleiotropic effect on eNOS activation. However, whether sEH phosphatase is involved in simvastatin-activated eNOS activity remains elusive. We investigated the role of sEH phosphatase activity in simvastatin-mediated activation of eNOS in endothelial cells (ECs). Simvastain increased the phosphatase activity of sEH, which was diminished by pharmacological inhibitors of sEH phosphatase. In addition, pharmacological inhibition of sEH phosphatase or overexpressing the inactive phosphatase domain of sEH enhanced simvastatin-induced NO bioavailability, tube formation and phosphorylation of eNOS, Akt and AMP-activated protein kinase (AMPK). In contrast, overexpressing the phosphatase domain of sEH limited the simvastatin-increased NO biosynthesis and eNOS phosphorylation at Ser1179. Simvastatin evoked epidermal growth factor receptor–c-Src–increased Tyr phosphorylation of sEH and formation of an sEH–Akt–AMPK–eNOS complex, which was abolished by the c-Src kinase inhibitor PP1 or c-Src dominant-negative mutant K298M. These findings suggest that sEH phosphatase activity negatively regulates simvastatin-activated eNOS by impeding the Akt–AMPK–eNOS signaling cascade.
Dysfunction of the frontolimbic region during swear word processing in young adolescents with Internet gaming disorder
Authors: Chun J-W , Choi J , Cho H , Lee S-K , Kim D J 
Published: August 2015

AbstractAlthough the Internet is an important tool in our daily life, the control of Internet use is necessary to address difficult problems. This study set out with the aim of assessing the cognitive control of affective events in Internet gaming disorder (IGD) and has examined the influence of IGD on neural activities with regard to swear words in young adolescents. We demonstrated the differences between adolescents with IGD and healthy control adolescents (HC) with respect to swear, negative and neutral word conditions. Swear words induced more activation in regions related to social interaction and emotional processing such as the superior temporal sulcus, right temporoparietal junction and orbitofrontal cortex (OFC) when compared with negative words. In this study, adolescents with IGD exhibited reduced activation in the right OFC related to cognitive control and in the dorsal anterior cingulate cortex (dACC) related to social rejection during the swear word condition. In addition, adolescents with IGD were negatively correlated with activity in the right amygdala toward swear words, indicating the important role of the amygdala in the control of aggression in adolescents with IGD. These findings enhance our understanding of social–emotional perception in adolescents with IGD.
Microstrip slow‐wave line for phase shifting cells
Authors: Gastaldi M. , Dragomirescu D. , Takacs A. , Armengaud V. , Rochette S. 
Published: August 2015

The design, simulation and measurements of microstrip slow‐wave lines implemented in a 0.25 µm SiGe bipolar CMOS (BiCMOS) process is addressed for Ku‐band (10–15 GHz) applications. The simulation results and the measurements show better performances for the proposed microstrip slow‐wave line compared with the classical microstrip transmission line. These lines present very low insertion losses and a high phase constant.
84 GBd (168 Gbit/s) PAM‐4 3.7 Vpp power DAC in InP DHBT for short reach and long haul optical networks
Authors: Konczykowska A. , Jorge F. , Dupuy J‐Y. , Riet M. , Nodjiadjim V. , Aubry H. , Adamiecki A. 
Published: August 2015

The architecture and performances of a multilevel driver for pulse amplitude modulation (PAM) formats, designed and fabricated in 0.7 µm InP double‐heterojunction bipolar transistor technology, are reported. The driver part is based on a power‐DAC architecture which is integrated with the multiplexing stage composed of three 2:1 selectors. Up to 100 GS/s operation was validated and PAM‐2, ‐4, ‐8 signals with high amplitude were measured. In particular, PAM‐4 at 84 GBd and PAM‐8 at 64 GBd operation was demonstrated with, respectively, a 3.7 and 4 Vpp differential output signal. This compact driver circuit is characterised by the highest merit factor in terms of high amplitude and the transmission capacity for an electronically generated multilevel signal.
Localising low‐level short‐circuit faults on the windings of power transformers based on low‐frequency response measurement of the transformer windings
Authors: Mahvi Mojtaba , Behjat Vahid 
Published: August 2015

Early detection and localisation of winding faults within the transformer can help make preventive actions and reduce potential damages to the transformer and the power system. This research work presents a new technique for sensitive detection and localisation of shorted turns on the windings of power transformers throughout low‐frequency response measurements of the transformer windings. To this end, using genetic algorithm, the detailed model of the damaged winding by the fault is estimated from the measured low‐frequency response data up to 10 kHz. The fault is localised along the winding by establishing the differences between the transfer functions of the healthy and faulty state of the winding units using statistical indicators. The experimental measurements which were made on a test transformer damaged by a low‐level short‐circuit fault proved that the newly developed method is sufficiently able and sensitive to detect and localise failures of only few shorted turns on the transformer windings.
Coplanar waveguide‐fed ultra‐wideband antenna with triple‐band notched design
Authors: Zhao Kun , Bai Dandan , Xia Yingqing , Wang Ying 
Published: August 2015

A novel coplanar waveguide‐fed ultra‐wideband antenna with triple band‐notched function centred at 3.5, 5.5 and 7.5 GHz is proposed. It has small size of 26 × 26 mm2. This antenna consists of an elliptical radiator and a square ground plane with an elliptical slot on one side of the substrate. Besides, two circles with a radius of 2 mm were dug from the edge of the outer ellipse to realise the bandwidth requirement. To avoid interference from Worldwide Interoperability for Microwave Access, a single open‐ended elliptical arc‐shaped slot was etched on the top side of the ground. Moreover, another elliptical arc‐shaped slot notched at wireless local area network band was etched on the elliptical radiator and two systemically C‐shaped slots working at 7.3–7.7 GHz was embedded on the structure. Measured voltage standing wave ratio shows the working frequency range was from 3.1 to 13.5 GHz except for notched bands of 3.35–3.8, 5.1–5.9 and 7.35–7.8 GHz.
Relationship between different push‐off variables and start performance in experienced swimmers
Authors: García‐Ramos Amador , Feriche Belén , de la Fuente Blanca , Argüelles‐Cienfuegos Javier , Strojnik Vojko , Strumbelj Boro , Štirn Igor 
Published: August 2015

AbstractThe objective of this study was to determine the relationship between different variables measured with a force plate during the swimming start push‐off phase and start performance presented by times to 5, 10 and 15 m. Twenty‐one women from the Slovenian national swimming team performed two different swim starts (freestyle and undulatory) on a portable force plate to a distance further than 15 m. Correlations between push‐off variables and times to 5, 10 and 15 m were quantified through Pearson's product‐moment correlation coefficient (r). The variables that significantly correlated (p < .05) to all times measured in the two starts performed were: average horizontal acceleration (freestyle: r = −0.58 to −0.71; and undulatory: r = −0.55 to −0.66), horizontal take‐off velocity (freestyle: r = −0.56 to −0.69; and undulatory: r = −0.53 to −0.67) and resultant take‐off velocity (freestyle: r = −0.53 to −0.65; and undulatory: r = −0.52 to −0.61). None of the variables derived from the vertical force were correlated to swimming start performance (p > .05). Based on the results of this study, we can conclude that horizontal take‐off velocity and average horizontal acceleration (calculated as the average horizontal force divided by swimmer's body mass) are the variables most related to swimming start performance in experienced swimmers, and therefore could be the preferred measures to monitor swimmers’ efficiency during the push‐off phase.
How functional programming mattered
Authors: Hu Zhenjiang , Hughes John , Wang Meng 
Published: August 2015

AbstractIn 1989 when functional programming was still considered a niche topic, Hughes wrote a visionary paper arguing convincingly ‘why functional programming matters’. More than two decades have passed. Has functional programming really mattered? Our answer is a resounding ‘Yes!’. Functional programming is now at the forefront of a new generation of programming technologies, and enjoying increasing popularity and influence. In this paper, we review the impact of functional programming, focusing on how it has changed the way we may construct programs, the way we may verify programs, and fundamentally the way we may think about programs.
Governance of algorithms: options and limitations
Authors: Saurwein Florian , Just Natascha , Latzer Michael 
Published: August 2015

Purpose– The purpose of this paper is to contribute to a better understanding of governance choice in the area of algorithmic selection. Algorithms on the Internet shape our daily lives and realities. They select information, automatically assign relevance to them and keep people from drowning in an information flood. The benefits of algorithms are accompanied by risks and governance challenges.Design/methodology/approach– Based on empirical case analyses and a review of the literature, the paper chooses a risk-based governance approach. It identifies and categorizes applications of algorithmic selection and attendant risks. Then, it explores the range of institutional governance options and discusses applied and proposed governance measures for algorithmic selection and the limitations of governance options.Findings– Analyses reveal that there are no one-size-fits-all solutions for the governance of algorithms. Attention has to shift to multi-dimensional solutions and combinations of governance measures that mutually enable and complement each other. Limited knowledge about the developments of markets, risks and the effects of governance interventions hampers the choice of an adequate governance mix. Uncertainties call for risk and technology assessment to strengthen the foundations for evidence-based governance.Originality/value– The paper furthers the understanding of governance choice in the area of algorithmic selection with a structured synopsis on rationales, options and limitations for the governance of algorithms. It provides a functional typology of applications of algorithmic selection, a comprehensive overview of the risks of algorithmic selection and a systematic discussion of governance options and its limitations.
Sketching the outline of a ghost: the fair balance between copyright and fundamental rights in intermediary third party liability
Authors: Angelopoulos Christina 
Published: August 2015

Purpose– The purpose of this article is to analyse the concept of a fair balance between conflicting fundamental rights in the context of intermediary liability for third party copyright infringement.Design/methodology/approach– European Legal Method.Findings– Fair balance is the appropriate conflict resolution mechanism in cases of fundamental rights clashes. Balancing is in essence a call for rational judicial deliberation. In intermediary liability, balancing excludes the imposition of filtering obligations on intermediaries for the purpose of copyright enforcement, but allows blocking.Originality/value– An in-depth look at a complicated, vague and underdeveloped area of law with significant practical effect.
The public’s interest in intermediaries
Authors: Mansell Robin 
Published: August 2015

Purpose– The purpose of this paper is to examine recent developments in European policy debates concerned with whether governments should intervene in the digital intermediary marketplace to protect the public’s interest.Design/methodology/approach– The paper discusses the public’s interest in the evolution of the digital intermediary marketplace, considers the economics and policy literature on the case for policy intervention in the market dynamics of digital platforms and examines the extent to which policy makers in Europe are catching up with changes in the market for digital platform services.Findings– It is argued that policy-makers need to broaden the evidence base upon which they consider whether policy intervention is needed beyond economic analysis. This is essential to ensure that the European digital intermediary marketplace develops in line with economic, social and cultural goals.Research limitations/implications– The case is made for measures to ensure continuous and integrated monitoring of developments in the digital marketplace based on economic indicators and evidence on the diversity of media content.Practical implications– Suggestions are made about the need for innovations in the way policy makers develop the required evidence base for their decisions.Social implications– The paper draws attention to the need for proactive policy making based on a consideration of economic, social and cultural goals to ensure that digital intermediaries are held accountable.Originality/value– The paper provides a multidisciplinary perspective on the dynamics of the digital intermediary ecology and assesses the extent to which the European digital market strategy provides an integrated initiative that is likely to be implemented.
Correctional interventions for women offenders: a rapid evidence assessment
Authors: Stewart Lynn , Gobeil Renée 
Published: August 2015

Purpose
– A Rapid Evidence Assessment (REA) determined the effectiveness of correctional programmes for women offenders and examined features of programmes providing the strongest outcomes. The paper aims to discuss these issues.

Design/methodology/approach
– Electronic databases and web sites were reviewed to identify literature focused on interventions with female offenders published since 2006, the end point of the last REA conducted in the area. The following retention criteria were applied: participants were over age 18; sample included women and results are reported separately for women; study included an appropriate comparison group; study included recidivism as an outcome measure. Studies’ methodological design quality was assessed using the Maryland Scientific Methods Scale.

Findings
– In total, one meta-analysis and 22 studies reflecting 17 unique samples, published from 2006 to December 2014, were identified. Overall, the best evidence suggests that the following programmes and approaches have an evidence base: first, substance abuse treatment, in particular in-custody or hierarchical therapeutic community programmes; second, gender-responsive programmes that emphasize existing strengths and competencies, as well as skills acquisition; and third, following in-custody programme treatment with participation in community follow-up sessions. There is also promising evidence for the use of community opioid maintenance among heroin addicted women.

Originality/value
– This review demonstrated that since 2006 the number of high-quality research studies assessing women’s correctional outcomes has grown considerably. The results provide guidance to programme designers and administrators on programmes for women offenders likely to be effective in promoting public safety goals and offender reintegration.
“Sharia on a Plate?” A critical discourse analysis of halal food in two Norwegian newspapers
Authors: Thomas Paul , Selimovic Amina 
Published: August 2015

Purpose– This study aims to explore how two Norwegian national online newspapers,DagbladetandAftenposten, have framed halal food in the past 6 years (2008-2014), a period conflating with a rise in Muslim demographics in Norway.Design/methodology/approach– A mixed-methods approach is used. Employing among others a Hallidayan transitivity analysis and other approaches from critical discourse analysis (CDA), clausal semantic structures, collocations and nominalizations were explored with a view toward fleshing out ideological significance. Particular attention was given to the neologism – “covert-Islamization” – popularized by the populist right-wing Progress Party.Findings– The findings reveal thatDagbladetrefracts halal food through a discourse of crime and other dubious frames tapping into topoi of Islamophobia. Halal is, in this manner, transformed into a synecdoche for deviance. This is contrasted withAftenposten’smore “halal-friendly” gaze which inter alia is attributed to greater access for Muslim contributors (over 40 per cent), with nearly all authorship penned in the aftermath of the Breivik massacre of July 22, 2011.Research limitations/implications– As a comparative research that explores two newspapers – albeit with substantial national circulation – there are obvious limitations. Future research could explore the contents ofVerdens Gang, the biggest newspaper in Norway, and perhaps incorporate iconic semiotic content.Social implications– The prevalent media discourse on halal in Norway casts a shadow over a fundamental aspect of the identity construction of Norwegians who adhere to Islam, thus highlighting issues of belonging and citizenry in the “new” Norway. National discourses of identity and belonging impact upon the Muslim consumer’s perception of self and ethnicity, and how these perceptions are negotiated in the interstices of a skewed media coverage of halal certainly serves to undermine this self-perception.Originality/value– Several recent studies have broached the subject of the manifold representations of Muslims and Islam in the media using a CDA, but there is a dearth in studies with a specific focus on halal food. This study contributes to the lacuna in the literature in an area of growing importance, not just as a socio-political and religious phenomenon, but a lucrative commercial project in a Scandinavian context.
Is there a market for Istihalah food product in Indonesia?
Authors: Aris Aadam T. , Zzaman Wahidu , Yang Tajul A. , Harivaindaran K.V. 
Published: August 2015

Purpose– This study aims to investigate the awareness of Muslim students regarding Istihalah in their daily life. The study was carried out to investigate attitude and awareness towards Istihalah among Muslim students in Universiti Pertanian Bogor (UPB), Indonesia.Design/methodology/approach– In total, 456 students were randomly selected from the university. A self-administered questionnaire was handed out to consenting students focusing on attitude and awareness towards Istihalah and eagerness to learn more about Istihalah.Findings– Results showed that Muslim students lacked information about Istihalah. From the total number of students 86.18 per cent agreed that information and knowledge of Istihalah is scarce. 40.1 per cent believed that Ulamas (Muslim scholars) are a very important source of knowledge regarding Istihalah, and 87.50 per cent are willing to learn more about Istihalah.Research limitations/implications– The respondents in this study were Muslim students in UPB, Indonesia. The results of this study are only applicable to the specific community. Thus, extrapolation of the results to represent society at large is not possible. The study merely attempts to investigate the prevalence of the concept among students of the university.Originality/value– This study is formed as a novel study to explore the attitude and awareness towards Istihalah among Muslim students in UPB, Indonesia. Students being representatives of the educated society are important links in creating awareness of the concept of Istihalah at large. This pilot study is the second of its kind, and prior study of Istihalah with regards to community awareness is limited to just one other performed by the same team.
LMX as a negative predictor of presenteeism climate
Authors: Ferreira Aristides I , Martinez Luis F. , Cooper Cary , Gui Diana M. 
Published: August 2015

Purpose– Some underlying mechanisms regarding presenteeism still remain unclear, namely, the construct of “presenteeism climate” and the importance of “leadership” Leader-Member Exchange (LMX) for presenteeism. In order to shed some light into this phenomenon, the purpose of this paper is to develop and apply a new scale of presenteeism climate.Design/methodology/approach– In Study 1, the authors identified a pool of items from the literature and, in Study 2 (n=147) the authors tested 26 items that were pilot studied with exploratory factor analysis. In Study 3 (n=293) the authors tested a three-factor model – extra-time valuation, supervision distrust and co-workers competitiveness – with confirmatory factor analysis.Findings– Results showed that LMX has a negative correlation with presenteeism climate. Study 3 also showed that this structure remained invariant with additional samples from employees working in hospitals from Ecuador (n=90) and China (n=237). Finally, the authors included suggestions for future studies to overcome the limitations of this research.Practical implications– This study has implications for managers and academics, as it emphasizes the importance of favorable behaviors between leaders and employees in order to decrease presenteeism and its adverse consequences.Originality/value– The main contribution consists of identifying dimensions of presenteeism climate and developing measures. Additionally, the authors contribute to the literature on leadership by studying the influence of LMX on presenteeism climate.
Workplace design
Authors: Karanika-Murray Maria , Michaelides George 
Published: August 2015

Purpose
– Although both job design and its broader context are likely to drive motivation, little is known about the specific workplace characteristics that are important for motivation. The purpose of this paper is to present the Workplace Characteristics Model, which describes the workplace characteristics that can foster motivation, and the corresponding multilevel Workplace Design Questionnaire.

Design/methodology/approach
– The model is configured as nine workplace attributes describing climate for motivation at two levels, psychological and organizational. The multilevel multi-time questionnaire was validated with data from 4,287 individuals and 212 workplaces and with integrated regulation as the criterion outcome.

Findings
– Multilevel factor analysis and regression indicated good internal reliability, construct validity, and stability over time, and excellent concurrent and predictive validity of the questionnaire.

Practical implications
– The model could help to optimize job and workplace design by contextualizing motivation. The questionnaire offers advancement over single-level climate measures as it is validated simultaneously at two levels. Further research can focus on overcoming the low response rate typical for online surveys, on need fulfillment as the mediating variable, and on the joint influence of job and workplace characteristics on organizational behavior.

Originality/value
– This work responds to calls to incorporate context in research into organizational behavior and job design. An understanding of the workplace is a first step in this direction. This questionnaire is the first to be validated at multiple levels of analysis. Ultimately, workplace design could support job design and the development of inherently motivating workplaces.