bluuebunny/crossref_metadata_2025_split huggingface dataset:
Family therapy and cognitive behavior therapy for eating disorders in children and adolescents in routine clinical care: a systematic review and meta-analysis
Authors: Wergeland Gro Janne , Ghaderi Ata , Fjermestad Krister , Enebrink Pia , Halsaa Lillan , Njardvik Urdur , Riise Eili N. , Vorren Gyri , Öst Lars-Göran 
Published: August 2024

AbstractFamily therapy for eating disorders (ED) is well-established and represents the treatment choice for ED in children and adolescents according to guidelines, with cognitive behavior therapy (CBT) as a second line treatment. There is limited knowledge about how these treatments work in routine clinical care. The goal of the present meta-analysis is to investigate the effectiveness of family therapy and CBT for various EDs in children and adolescents when carried out in routine clinical care. Ovid MEDLINE, Embase OVID, and PsycINFO were searched for articles published until December 2023. The outcome of family therapy and CBT, methodological quality, risk of bias, and moderators of treatment outcome were examined and benchmarked by meta-analytically comparing with ED efficacy studies. Forty-four effectiveness studies comprising 3251 family therapy or CBT patients were included. Large to very large within-group effect sizes (ES) were found for ED-psychopathology (0.80) and weight measures for AN (1.64) at post treatment. The attrition rate was 15%. Risk of bias was considerable. Moderate to large ES were found for family therapy and CBT, respectively. The benchmarking analysis showed that effectiveness studies had comparable ESs to efficacy studies (0.80 and 0.84 for the ED-psychopathology at post treatment). The findings support family therapy and CBT for ED in children and adolescents as effective treatments when delivered in routine clinical care, with effects comparable with those found in efficacy studies. The evidence needs to be interpreted with caution because of the risk of bias in a high proportion of studies.PROSPERO [CRD42023441794].
Drug Trafficking as Crime Against Humanity: Global Moral Panics and Drugs at the United Nations
Authors: Mostyn Ben 
Published: August 2024

Abstract
This article presents archival data produced by Australian diplomats in the 1980s that report on the ‘drug problem’ in various host countries. The reports reveal growing concern in many countries at a rapid increase in drug use. The second half of the article focusses on diplomatic reports from the United Nations where discussions were beginning about creating a third convention against drug trafficking. These early drafts of the convention labelled drug trafficking a ‘crime against humanity’—a criminal charge that had not been prosecuted since the Nuremburg trials. The article applies elements of moral panic theory, neorealism, and the sociology of punishment. Combining these theories suggests that condemning drug traffickers in the 1980s allowed diplomats to create a global social solidarity that may have helped end the Cold War.
Fostering Play in the COVID Crisis: Insights from Infant-Toddler Teachers
Authors: Shin Minsun 
Published: August 2024

AbstractPlay is pivotal in supporting young children’s holistic development. The COVID-19 crisis further highlighted the importance of play in supporting children’s well-being and in providing a sense of normalcy. Guided by the phenomenographic method, this study aimed to examine Korean in-service infant-toddler teachers’ experiences in fostering play in early childhood educational classrooms during the COVID-19 crisis. The study involved 10 infant-toddler teachers working with children under the age of three years at a large university-based childcare center. They participated in drawing tasks and in-person focus group interviews. The findings revealed that the pandemic caused and exacerbated barriers to everyday play. However, despite challenges, the participants demonstrated their strong commitment to play in the classroom, exhibiting resilience, adaptability, creativity, and resourcefulness. They continued to create a playful environment, support play in various forms, and prioritize play-based learning, demonstrating their strong commitment to play. One notable change expressed by the participants was limited social interaction during mealtime. This study found that the much-needed, unavoidable public health interventions during the COVID-19 crisis may have resulted in unintended consequences for infants’ and toddlers’ social-emotional and language development. Such findings reinforce the idea that play should remain at the forefront of education during the pandemic and beyond.
Gambling habits and Probability Judgements in a Bayesian Task Environment
Authors: Dickinson David L. , Reid Parker 
Published: August 2024

AbstractLittle is known about how gamblers form probability assessments. This paper reports on a preregistered study that administered an incentivized Bayesian choice task to n = 465 self-reported gamblers and non-gamblers. The task elicits subjective probability assessments and allows one to estimate the degree to which distinct information sources are weighted in forming probability assessments. Our data failed to support our main hypotheses that experienced online gamblers would be more accurate than non-gamblers in estimating probabilities, that gamblers experienced in games of skill (e.g., poker) would be more accurate than gamblers experienced only in non-skill games (e.g., slots), that accuracy would differ by sex, or that information sources would be weighted differently across different participant groups. Exploratory analysis, however, revealed that gambling frequency predicted lower Bayesian accuracy, while cognitive reflection predicted higher accuracy. The decline in accuracy linked to self-reported gambling frequency was stronger for female participants. Decision modeling estimated a decreased weight place on new evidence (over base rate odds) for those participant groups who showed decreased accuracy, which suggests that a proper incorporation of new information is important for probability assessments. Our results link online gambling frequency to worse performance in the critical probability assessment skills that should benefit gambling success (i.e., in skill-based games). Additional research is needed to better understand the mechanism linking reported gambling frequency to probability assessment accuracy.
Kinetic Inductance Detectors for the CADEx Experiment: Searching for Axions in the W-Band
Authors: Rodriguez David , de Ory Marina C. , Aja Beatriz , de la Fuente Luisa , Gallego Juan Daniel , Villa Enrique , Pascual Juan Pablo , Artal Eduardo , Granados Daniel , Martin-Pintado Jesus , Gomez Alicia 
Published: August 2024

AbstractThis paper presents the detector developments for the Canfrac Axion Detection Experiment (CADEx), aiming at detecting dark matter axions and dark photons within the W-band. A proof of concept of the detection system is based on an array of lumped-element kinetic inductance detectors (LEKIDs). Microstrip technology is used as read-out scheme, and the ground plane acts as backshort for optimizing optical absorption in the W-band. A titanium/aluminum bilayer is used for ensuring detection below 100 GHz. The detector array design includes an inner active section consisting of 36 detectors for direct detection of the axion signal and an additional outer rim of 28 blind pixels for calibration purposes. The nanofabrication process and a preliminary cryogenic characterization are presented, being the results in good agreement with the frequency design. Measured devices exhibit coupling quality factors of the order of 6 × 104, internal quality factors above 105 and an estimated kinetic inductance of 3.3 pH/□.
Faithfulness of Real-Space Renormalization Group Maps
Authors: Akamatsu Katsuya O. , Kawashima Naoki 
Published: August 2024

AbstractThe behavior of $$b=2$$

b
=
2

real-space renormalization group (RSRG) maps like the majority rule and the decimation map was examined by numerically applying RSRG steps to critical $$q=2,3,4$$

q
=
2
,
3
,
4

Potts spin configurations. While the majority rule is generally believed to work well, a more thorough investigation of the action of the map has yet to be considered in the literature. When fixing the size of the renormalized lattice $$L_g$$

L
g

and allowing the source configuration size $$L_0$$

L
0

to vary, we observed that the RG flow of the spin and energy correlation under the majority rule map appear to converge to a nontrivial model-dependent curve. We denote this property as “faithfulness”, because it implies that some information remains preserved by RSRG maps that fall under this class. Furthermore, we show that $$b=2$$

b
=
2

weighted majority-like RSRG maps acting on the $$q=2$$

q
=
2

Potts model can be divided into two categories, maps that behave like decimation and maps that behave like the majority rule.
Stereotactic radiosurgery for brain metastases from human epidermal receptor 2 positive breast Cancer: an international, multi-center study
Authors: Pikis Stylianos , Mantziaris Georgios , Protopapa Maria , Tos Salem M. , Kowalchuk Roman O. , Ross Richard Blake , Rusthoven Chad G. , Tripathi Manjul , Langlois Anne-Marie , Mathieu David , Lee Cheng-Chia , Yang Huai-che , Peker Selcuk , Samanci Yavuz , Zhang Michael Yu , Braunstein Steve E. , Wei Zhishuo , Niranjan Ajay , Lunsford Dade L. , Sheehan Jason 
Published: August 2024

Abstract
Purpose
To report patient outcomes and local tumor control rates in a cohort of patients with biopsy-proven HER-2 positive breast cancer treated with stereotactic radiosurgery (SRS) for brain metastases (BM).

Methods
This international, retrospective, multicenter study, included 195 female patients with 1706 SRS-treated BM. Radiologic and clinical outcomes after SRS were determined and prognostic factors identified.

Results
At SRS, median patient age was 55 years [interquartile range (IQR) 47.6–62.0], and 156 (80%) patients had KPS ≥ 80. The median tumor volume was 0.1 cm3 (IQR 0.1–0.5) and the median prescription dose was 16 Gy (IQR 16–18). Local tumor control (LTC) rate was 98%, 94%, 93%, 90%, and 88% at six-, 12-, 24-, 36- and 60-months post-SRS, respectively. On multivariate analysis, tumor volume (p = < 0.001) and concurrent pertuzumab (p = 0.02) improved LTC. Overall survival (OS) rates at six-, 12-, 24-, 36-, 48-, and 60-months were 90%, 69%, 46%, 27%, 22%, and 18%, respectively. Concurrent pertuzumab improved OS (p = 0.032). In this patient subgroup, GPA scores ≥ 2.5 (p = 0.038 and p = 0.003) and rare primary tumor histologies (p = 0.01) were associated with increased and decreased OS, respectively. Asymptomatic adverse radiation events (ARE) occurred in 27 (14.0%) and symptomatic ARE in five (2.6%) patients. Invasive lobular carcinoma primary (p = 0.042) and concurrent pertuzumab (p < 0.001) conferred an increased risk for overall but not for symptomatic ARE.

Conclusion
SRS affords effective LTC for selected patients with BM from HER-2 positive breast cancer. Concurrent pertuzumab improved LTC and OS but at the same time increased the risk for overall, but not symptomatic, ARE.
Small business stories in the formation of enterprise policy: a narrative policy analysis of the UK Bolton Committee
Authors: Wapshott Robert , Mallett Oliver 
Published: August 2024

AbstractEnterprise policy, which seeks to stimulate start-ups and support small businesses, attracts significant investment from government and shapes the context for entrepreneurs. Researchers have begun to study the processes underlying the formulation of enterprise policy. However, accounts of how competing interests seek to influence enterprise policymaking processes remain rare. Utilising a distinctive approach to narrative entrepreneurship, developed through a narrative policy analysis, we examine archival records of submissions from a range of stakeholders to a UK government inquiry. We develop a narrative entrepreneurship approach that allows us to analyse the stories and broader narratives told by entrepreneurs and others. Our analysis identifies different types of narrative strategy used to develop stories by two competing interest groups: a narrative from small businesses and their representatives and, contesting this, a counternarrative from other stakeholders, including the finance industry, consumer groups and large firms. We analyse how the inquiry engaged with these competing narratives and sought to make them amenable to policymaking through the creation of a simplifying, overarching metanarrative. We demonstrate that, while this metanarrative simplified the uncertain, complex and polarised issue of enterprise policy, it masked and did not resolve the underlying tensions between competing interests.
A non-causalist account of the explanatory autonomy in the psychological sciences
Authors: Díez José , Pineda David 
Published: August 2024

AbstractIt has been often claimed that physicalism challenges the explanatory autonomy of psychological sciences. Most who advocate for such explanatory autonomy and do not want to renounce to physicalism, presuppose a causalist account of explanatoriness and try to demonstrate that, adequately construed, (causal) psychological explanations are compatible with (some sufficient version of) physicalism. In Sect. 1 we summarize the different theses and assumptions involved in the seeming conflict between explanatory autonomy and physicalism. In Sect. 2 we review the main attempts to make them compatible assuming a causalist account of explanation and argue that none succeeds. In Sect. 3 we introduce a recent, non-causalist account of scientific explanation as ampliative, specialized embedding (ASE) that has been successfully applied to other fields. In Sect. 4 we apply ASE to elucidate two paradigmatic cognitive explanations of psychological phenomena: déjà vu and action production. We conclude that ASE elucidates well the autonomy of the cognitive explanations of these phenomena independently of what finally happens with the causal exclusion problem and that it may be generalized to other psychological explanations.
Small amendment arguments: how they work and what they do and do not show
Authors: van Hees Martin , Jitendranath Akshath , Luttens Roland Iwan 
Published: August 2024

Abstract
The small improvement argument has been said to establish that the standard weak preference or value relation can be incomplete. We first show that the argument is one of three possible ‘small amendment arguments’, each of which would yield the same conclusion. Generalizing the analysis thus, we subsequently present a strong and a weak version of small amendment arguments and derive the exact rationality conditions under which they reveal incompleteness. The results show that the arguments (in any of their variants) need not reveal a problem for the possibility of rational choice. In fact, it can be argued that they only reveal such a problem if the underlying relation is complete rather than incomplete.
Development of 52Mn Labeled Trastuzumab for Extended Time Point PET Imaging of HER2
Authors: Omweri James M. , Saini Shefali , Houson Hailey A. , Tekin Volkan , Pyles Jennifer M. , Parker Candace C. , Lapi Suzanne E. 
Published: August 2024

Abstract
Purpose
Due to their long circulation time in the blood, monoclonal antibodies (mAbs) such as trastuzumab, are usually radiolabeled with long-lived positron emitters for the development of agents for Positron Emission Tomography (PET) imaging. Manganese-52 (52Mn, t1/2 = 5.6 d, β+  = 29.6%, E(βave) = 242 keV) is suitable for imaging at longer time points providing a complementary technique to Zirconium-89 (89Zr, t1/2 = 3.3 d, β+  = 22.7%, E(βave) = 396 keV)) because of its long half-life and low positron energy. To exploit these properties, we aimed to investigate suitable bifunctional chelators that could be readily conjugated to antibodies and labeled with 52Mn under mild conditions using trastuzumab as a proof-of-concept.

Procedures
Trastuzumab was incubated with S-2-(4-isothiocyanatobenzyl)-1,4,7,10-tetraazacyclododecane tetraacetic acid (p-SCN-Bn-DOTA), 1-Oxa-4,7,10-tetraazacyclododecane-5-S-(4-isothiocyantobenzyl)-4,7,10-triacetic acid (p-SCN-Bn-Oxo-DO3A), and 3,6,9,15-tetraazabicyclo[9.3.1] pentadeca-1(15),11,13-triene-4-S-(4-isothiocyanatobenzyl)-3,6,9-triacetic acid (p-SCN-Bn-PCTA) at a tenfold molar excess. The immunoconjugates were purified, combined with [52Mn]MnCl2 at different ratios, and the labeling efficiency was assessed by iTLC. The immunoreactive fraction of the radiocomplex was determined through a Lindmo assay. Cell studies were conducted in HER2 + (BT474) and HER2- (MDA-MB-468) cell lines followed by in vivo studies.

Results
Trastuzumab-Oxo-DO3A was labeled within 30 min at 37 °C with a radiochemical yield (RCY) of 90 ± 1.5% and with the highest specific activity of the chelators investigated of 16.64 MBq/nmol. The labeled compound was purified with a resulting radiochemical purity of > 98% and retained a 67 ± 1.2% immunoreactivity. DOTA and PCTA immunoconjugates resulted in < 50 ± 2.5% (RCY) with similar specific activity. Mouse serum stability studies of [52Mn]Mn-Oxo-DO3A-trastuzumab showed 95% intact complex for over 5 days. Cell uptake studies showed higher uptake in HER2 + (12.51 ± 0.83% /mg) cells compared to HER2- (0.85 ± 0.10%/mg) cells. PET images of mice bearing BT474 tumors showed high tumor uptake that was consistent with the biodistribution (42.02 ± 2.16%ID/g, 14 d) compared to MDA-MB-468 tumors (2.20 ± 0.80%ID/g, 14 d). Additionally, both models exhibited low bone uptake of < 1% ID/g.

Conclusion
The bifunctional chelator p-SCN-Bn-Oxo-DO3A is promising for the development of 52Mn radiopharmaceuticals as it was easily conjugated, radiolabeled at mild conditions, and illustrated stability for a prolonged duration both in vitro and in vivo. High-quality PET/CT images of [52Mn]Mn-Oxo-DO3A-trastuzumab were obtained 14 d post-injection. This study illustrates the potential of [52Mn]Mn-Oxo-DO3A for the evaluation of antibodies using PET imaging.
Die Selbsteinschätzung der sozialen Partizipation von Schüler*innen in der Sekundarstufe I – Welche Rolle spielen sonderpädagogische Förderbedarfe der Schüler*innen und Merkmale der Lehrkräfte?
Authors: Labsch Amelie , Külker Lena , Grosche Michael 
Published: August 2024

ZusammenfassungSoziale Partizipation aller Schüler*innen ist ein wichtiges Ziel schulischer Inklusion. Laut Rahmenkonzept zu Heterogenität im Unterricht sind dafür einerseits individuelle Schüler*innenmerkmale und andererseits solche ihrer Lehrkräfte zentral. Allerdings zeigt sich mehrheitlich, dass Schüler*innen mit sonderpädagogischen Förderbedarfen (SPF) weniger sozial partizipieren als ihre Mitschüler*innen. Obwohl vereinzelt belegt wurde, dass dieser Unterschied bei positiver Einstellung von Lehrkräften gegenüber Inklusion geringer ausfällt, dienen Lehrkraftmerkmale nur selten zur Erklärung von sozialer Partizipation. Zudem wird das Konstrukt meist unterschiedlich operationalisiert und selten wird ein umfängliches Bild über verschiedene Dimensionen sozialer Partizipation erhoben. Der Beitrag betrachtet daher, wie Schüler*innen mit und ohne SPF in inklusiven Klassen ihre soziale Partizipation über die Dimensionen „Kontakte/Interaktionen“, „Akzeptanz/Unterstützung“, „Freundschaft/Beziehung“ und „Selbstwahrnehmung der Partizipation“ einschätzen und welche Rolle dabei Merkmale ihrer Lehrkräfte spielen. Erwartet wird, (1) dass Schüler*innen mit SPF weniger sozial partizipieren als diejenigen ohne SPF, (2) dass eine positive Einstellung der Lehrkräfte gegenüber Inklusion, ein hohes Verantwortungsgefühl gegenüber ihren Schüler*innen sowie eine hohe inklusionsbezogene Selbstwirksamkeit mit mehr sozialer Partizipation einhergehen und (3) diese zugleich den Unterschied zwischen Schüler*innen mit und ohne SPF verringern. Analysegrundlage sind u. a. Daten von Schüler*innen mit und ohne SPF der 7. Klasse des INSIDE-Projekts (n = 1506, davon n = 170 mit SPF aus 331 Klassen). Mehrebenenanalytisch betrachtet schätzen Schüler*innen mit SPF ihre soziale Partizipation auf beinahe allen Dimensionen geringer ein als diejenigen ohne SPF. Die Lehrkraftmerkmale erklären diese Effekte nicht. Zudem wirkt nur die Einstellung der Lehrkräfte differenziell: Hypothesenkonträr berichten Schüler*innen mit SPF bei höherer Einstellung gegenüber Inklusion von weniger Kontakten/Interaktionen zu Gleichaltrigen. Die Ergebnisse werden diskutiert und interpretiert.
Interplays between relational and instrumental values: insights from research experiences on human–nature relations
Authors: Riechers Maraja , Pearson Jasmine , Diaz-Cruz Nataly , Ortiz-Przychodzka Stefan , Topp Emmeline 
Published: August 2024

Abstract
Relational values have become increasingly recognised within the field of social–ecological systems as an innovative and in-depth approach to uncovering the value of human–nature relationships around the world. As an emerging concept within mainstream Western academia, there is still much to learn about the potential challenges of working with relational values and how to navigate them in applied research. Drawing on empirical research from Colombia, Fiji, Germany, Romania and South Africa, this paper explores the key themes which emerged when working with human–nature relationships. We reveal complex interconnections between relational and instrumental values, livelihood practices and power and politics. We conclude by highlighting the importance of acknowledging the fluidity of relational values and their potential to bridge different worldviews and knowledge systems between researchers and communities.
Colorectal Leiomyosarcoma: Demographics Patterns, Treatment Characteristics, and Survival Analysis in the U.S. Population
Authors: Yasinzai Abdul Qahar Khan , Lee Kue Tylor , Khan Imran , Tareen Bisma , Sohail Amir Humza , Iqbal Asif , Khan Israr , Waheed Abdul , Ramamoorthy Bhavishya U. , Ullah Asad , Blakely Andrew M. 
Published: August 2024

Abstract
Background
Colorectal leiomyosarcoma (CR-LMS) is a rare neoplasm arising from smooth muscle cells. It accounts for less than 0.1% of all colorectal malignancies. In this population-based study, we aim to understand the demographics, treatment characteristics, and pathologic factors associated with survival in CR-LMS.

Methods
Data from the SEER Program (2000–2018) were analyzed using SEER*Stat and SPSS. Statistical methods included descriptive analysis, Kaplan–Meier survival curves, log-rank tests, and Cox proportional hazards regression to assess the impact of various factors on disease-specific and overall survival.

Results
A total of 191 cases of CR-LMS were identified. Most patients were 60–69 years of age (median: 64 years) and Caucasian (78%). There was nearly the same distribution in sex (M:F ratio; 1:1.2). The overall 5-year observed survival was 50.3% (95% C.I., 46.3—54.2). The 5-year disease-specific survival (DSS) was 66.1% (95% C.I., 62.0—70.1). The 5-year overall survival after resection was 60.8% (95% C.I., 56.3—65.3). Multivariable analysis identified grades III and IV (p = 0.028) as negative predictors of overall survival. Regional spread and distant stage are negative predictors of overall survival (p < 0.01).

Conclusion
Our data reveals that colorectal leiomyosarcoma (CR-LMS) often presents in patients around 64 years old with advanced stages and poor differentiation. Key adverse prognostic factors include older age, high tumor grade, large tumor size, and distant metastases, with surgical resection showing the best survival outcomes. To improve outcomes, further research and consolidation of data are essential for developing targeted therapies and comprehensive guidelines.