bluuebunny/crossref_metadata_2025_split huggingface dataset:
Using intrinsic‐resonance of an interdigitated microwave capacitor for detecting glyphosate‐based herbicide in water
Authors: Méndez‐Jerónimo Gabriela , Lobato‐Morales Humberto , Molina‐Reyes Joel 
Published: August 2024

AbstractGlyphosate‐based herbicides are the most used worldwide despite the fact that studies have shown their possible adverse effects on human health and the environment. Since the residues of these herbicides reach water bodies, their detection is considered an emergent research topic. In this work, the use of the intrinsic resonance of a microwave interdigitated capacitor fabricated on microstrip technology, is proposed for detecting the presence of glyphosate‐based herbicide in water. In addition, a sample holder is proposed to avoid the possible oxidation of the metal electrodes due to the direct contact with liquids. The proposed structure was designed to present its first intrinsic resonance at 1.95 GHz so that this resonance is shifted to 1.58 GHz when pure deionized water is used as sample. The sensor device was tested against 18 mixtures prepared with concentrations between 0% and 100% v/v of herbicide diluted in deionized water. Experimental measurements confirm that by using the intrinsic resonance parameters of the proposed structure, is possible to detect the presence of a glyphosate‐based herbicide. Finally, the results confirm the potential of the proposal as an alternative for real‐time, label‐free, and sensitive detection of glyphosate in water and they open the possibility of exploiting its use for the detection of other contaminants.
Reproducibility of intravoxel incoherent motion quantification in the liver across field strengths and gradient hardware
Authors: Simchick Gregory , Allen Timothy J. , Hernando Diego 
Published: August 2024

AbstractPurposeTo evaluate reproducibility and interlobar agreement of intravoxel incoherent motion (IVIM) quantification in the liver across field strengths and MR scanners with different gradient hardware.MethodsCramer‐Rao lower bound optimization was performed to determine optimized monopolar and motion‐robust 2D (b‐value and first‐order motion moment [M1]) IVIM‐DWI acquisitions. Eleven healthy volunteers underwent diffusion MRI of the liver, where each optimized acquisition was obtained five times across three MRI scanners. For each data set, IVIM estimates (diffusion coefficient (D), pseudo‐diffusion coefficients ( and ), blood velocity SDs (Vb1 and Vb2), and perfusion fractions [f1 and f2]) were obtained in the right and left liver lobes using two signal models (pseudo‐diffusion and M1‐dependent physical) with and without T2 correction (fc1 and fc2) and three fitting techniques (tri‐exponential region of interest–based full and segmented fitting and blood velocity SD distribution fitting). Reproducibility and interlobar agreement were compared across methods using within‐subject and pairwise coefficients of variation (CVw and CVp), paired sample t‐tests, and Bland–Altman analysis.ResultsUsing a combination of motion‐robust 2D (b‐M1) data acquisition, M1‐dependent physical signal modeling with T2 correction, and blood velocity SD distribution fitting, multiscanner reproducibility with median CVw = 5.09%, 11.3%, 9.20%, 14.2%, and 12.6% for D, Vb1, Vb2, fc1, and fc2, respectively, and interlobar agreement with CVp = 8.14%, 11.9%, 8.50%, 49.9%, and 42.0%, respectively, was achieved.ConclusionRecently proposed advanced IVIM acquisition, signal modeling, and fitting techniques may facilitate reproducible IVIM quantification in the liver, as needed for establishment of IVIM‐based quantitative biomarkers for detection, staging, and treatment monitoring of diseases.
Development and characterization of UV‐curable PCL/AESO/CNT nanocomposites for biomedical engineering
Authors: Mohammadi Zahra , Mirzaei Hadis , Moradi Elahe , Bolourian Amirali , Bazrpash Sina , Tavakoli Dare Masoud , Khonakdar Hossein Ali 
Published: August 2024

AbstractThis study investigates the development and characterization of UV‐curable Poly(ε‐caprolactone) (PCL), Acrylated Epoxidized Soybean Oil (AESO), and Carbon Nanotubes (CNT) nanocomposites for biomedical engineering applications. The PCL/AESO blends were prepared in various ratios, and CNTs were incorporated at concentrations of 0.5, 1.0, and 1.5 wt% to enhance mechanical properties. The UV‐curable formulations aimed to leverage rapid curing times, precise control over material properties, and the ability to fabricate complex structures. Results indicated that the incorporation of CNTs improved the tensile strength, modulus, and toughness of the composites. The PCL/AESO/CNT nanocomposites exhibited a tensile strength increase of 25%, a modulus improvement of 30%, and a toughness enhancement of 20% compared to pure PCL. Thermal analysis showed an increase in crystallization temperature and thermal stability, with a crystallinity degree of 63.31% and a maximum degradation temperature of 407°C for the B/C 50/50/1.5 sample. Biocompatibility assessments using L929 fibroblast cells revealed that the composites supported cell viability and proliferation over 7 days with negligible cytotoxicity. Cell attachment studies indicated favorable morphology and adherence, suggesting a conducive environment for cell growth and differentiation. Hydrolytic biodegradation studies demonstrated adjustable degradation rates, making these composites suitable for various biomedical applications requiring controlled biodegradation.
Theoretical investigations on N2H5N5/PDO cocrystal via a first‐principles study
Authors: Chen Zhipeng , Wang Junqi , Xie Qingshan , Yang Chen , Zhou Changlin 
Published: August 2024

AbstractThe exploration of cyclo‐N5ˉ‐based energetic cocrystals represents a noteworthy avenue within pentazolate chemistry, focusing on leveraging cocrystallization to enhance stability. Recently, a novel cocrystal explosive, N2H5N5/PDO, was developed by combining N2H5N5 with pyrazine 1,4‐dioxide (PDO), exhibiting promising detonation characteristics and reduced sensitivity. This study endeavors to elucidate how the structure and noncovalent interactions impact the performance of N2H5N5/PDO through a first‐principles investigation. The results indicate that the enhanced hydrogen bonding and wave‐like crystal packing structure within the cocrystal effectively bolster its stability compared to N2H5N5. The N···H and O···H interactions, in conjunction with π–π interactions, emerge as critical elements driving cocrystal formation. Compared to the pure N2H5N5, the detonation performance of the cocrystal exhibits a slight decline, albeit with a noticeable reduction in sensitivity.
Novel Trifunctional Intramolecular Frustrated Lewis Pair Derived From Aminoboronic Acid for Converting CO2 Into Valuable Chemicals
Authors: Faizan Mohmmad , Santhosh Guntupalli , Chakraborty Madhumita , Pawar Ravinder 
Published: August 2024

ABSTRACTThe conversion of CO2 into valuable chemicals remains a significant challenge for achieving environmental sustainability, primarily due to the stability of the CO2 molecule. This necessitates the development of efficient and ecofriendly catalysts. In recent years, frustrated Lewis pairs (FLPs) have shown promise for CO2 utilization. In this study, we introduce α‐aminodiboronic acid (DBA), a novel trifunctional aminoboronic acid, as an intramolecular FLP for converting CO2 into cyclic carbonate and formic acid. Using density functional theory (DFT) calculations, we explored the reaction mechanism and investigated DBA's electronic structure through molecular electrostatic potential surface (MESP) and natural bond orbital (NBO) analyses. Our results reveal that one −B (OH)2 group induces an unusual state of frustration in the molecule due to charge transfer from the nitrogen atom's lone pair to the π* orbitals, enhancing catalytic performance. The additional −B (OH)2 group serves as an anchoring site for reactive species. The epoxide activation energy is reduced by approximately 27 kcal/mol compared to the uncatalyzed reaction, and the reduction of CO2 occurs with a requirement of 26 kcal/mol. The additional −B (OH)2 plays a crucial role in the catalytic mechanism and minimizes the energies of various structures observed in the reaction path. The reaction energetics align with structural analysis observations, marking this study as the first report on single‐molecule trifunctional FLPs for transforming CO2 into valuable chemicals.
“Fight or flight”—A study of frontline emergency response workforce's perceived knowledge, and motivation to work during hazards
Authors: Sørensen Jarle L. , Mortelmans Luc , Gray Lesley , Khorram‐Manesh Amir , Hertelendy Attila J. , Stray Karianne N. , Kupietz Kevin , Peyravi Mahmoud R. , Ranse Jamie , Achour Nebil 
Published: August 2024

AbstractThis study aims to identify different frontline emergency response workforce's perceived knowledge of hazards and their willingness and motivations to go to work during them. An online version of the “Fight or Flight” survey was distributed and collected from Norwegian emergency personnel during the spring of 2023. Findings reveal a gap between the participants' knowledge levels and their overall willingness to go to work. Furthermore, the study identified family safety as the main motivational factor. The study shows the need for educational initiatives, and for managers to incorporate the knowledge of employee motivational factors into their hiring processes, frameworks, and management systems to ensure the best possible working conditions for their employees and their families.
3D‐Printed Carbon Scaffold for Structural Lithium Metal Batteries
Authors: Katsuyama Yuto , Hui Joanne , Thiel Markus , Haba Nagihiro , Yang Zhiyin , Kaner Richard B. 
Published: August 2024

AbstractFocus on advancement of energy storage has now turned to curbing carbon emissions in the transportation sector by adopting electric vehicles (EVs). Technological advancements in lithium‐ion batteries (LIBs), valued for their lightweight and high capacity, are critical to making this switch a reality. Integrating structurally enhanced LIBs directly into vehicular design tackles two EV limitations: vehicle range and weight. In this study, 3D‐carbon (3D‐C) lattices, prepared with an inexpensive stereolithography‐type 3D printer followed by carbonization, are proposed as scaffolds for Li metal anodes for structural LIBs. Mechanical stability tests revealed that the 3D‐C lattice can withstand a maximum stress of 5.15 ± 0.15 MPa, which makes 3D‐C lattices an ideal candidate for structural battery electrodes. Symmetric cell tests show the superior cycling stability of 3D‐C scaffolds compared to conventional bare Cu foil current collectors. When 3D‐C scaffolds are used, a small overpotential (≈0.075 V) is retained over 100 cycles at 1 mA cm−2 for 3 mAh cm−2, while the overpotential of a bare Cu symmetric cell is unstable and increased to 0.74 V at the 96th cycle. The precisely oriented internal pores of the 3D‐C lattice confine lithium metal deposits within the 3D scaffold, effectively preventing short circuits.
It's about time: A multistate semicontinuous time mark–recapture model to evaluate seasonal survival and movement rates of juvenile Coho Salmon in a small coastal watershed
Authors: Van Vleet Nicholas P. , Ward Darren M. , Som Nicholas A. , Barton Daniel C. , Anderson Colin , Henderson Mark J. 
Published: August 2024

Abstract

Objective
Many mark–recapture models assume that releases and recaptures are discrete events, and researchers often aggregate continuous recapture data (e.g., passive integrated transponder [PIT] detections) into coarse temporal scales to satisfy this assumption. This temporal discretization could result in parameter biases by ignoring the individual heterogeneity in the time susceptible to mortality after recapture and the conditions experienced (e.g., temperature and predation risk) before and after recapture. Our objectives were to (1) estimate the amount of bias in survival and emigration rates due to different temporal discretization durations when recapture events occur continuously and (2) apply this semicontinuous model to estimate rates of early emigration and overwinter survival for Coho Salmon Oncorhynchus kisutch in a coastal California watershed.

Methods
We developed a semicontinuous time multistate mark–recapture model to separately estimated emigration and survival rates throughout the year. We used weekly time-varying occasions paired with discrete spatial states and conducted extensive simulation trials to explore potential model bias. We then applied the model to an existing 4-year dataset of Coho Salmon PIT tag detections.

Result
Our simulations indicated that that the amount of bias in survival and movement rates decreased as the temporal discretization duration decreased. The confidence interval of the bias estimates included zero with a duration of 8 days, indicating that this duration was sufficiently short to model movement and survival. Results from our Coho Salmon analysis suggest that overwinter survival rate ranged from 0.72 to 0.83, which is higher than previous estimates for Coho Salmon in this region. We estimate that a substantial proportion of smaller juveniles (0.21–0.28 annually) move to downstream nonnatal rearing habitats before the spring smolt migration.

Conclusion
Our semicontinuous modeling approach can be implemented relatively easily and used to analyze continuous detection data to accurately estimate survival and movement rates. Our analysis of Coho Salmon PIT tag detections implies that previous low estimates of apparent overwinter survival of Coho Salmon were partially due to high movement rates to alternative rearing locations. This contrasts with conclusions from the previous research that suggested that overwinter survival was a major limiting factor for population recovery and implies that species recovery may be improved by considering multiple emigration patterns in the design of future research, monitoring, and restoration projects.
Green synthesis and anti‐biofilm effect on Drosophila melanogaster of selenium nanoparticles from Vitis vinifera for photocatalytic degradation and different biological applications
Authors: Banerjee Manosi , Rajeswari Devi 
Published: August 2024

AbstractThis study aims to combine Vitis vinifera extract with sodium selenite (Na2SeO3) solution to develop a biobased approach for producing green selenium nanoparticles. V. vinifera fruit extract is potent in secondary metabolites such as phenols (1.19 mg gallic acid equivalents/g), flavonoids (0.42 mg catechin equivalents/g), and tannins (2.84 mg tannic acid equivalents/g), it was discovered to be particularly appropriate for the production of nanoparticles. SeNPs were characterized using UV–vis, SEM, zeta potential, EDS, DLS, FTIR, and XRD AFM. SeNPs were assessed for anti‐microbial, anti‐biofilm, and antioxidant assay. Biosynthesized‐produced SeNPs were discovered to possess significant antioxidant activity and high antibacterial action. Selenium nanoparticles had the potential to modulate the impact of Pseudomonas aeruginosa on Drosophila melanogaster. Molecular analyses were performed, and survival analysis curves were plotted to study the impact of SeNPs. When SeNPs are exposed to UV light, they efficiently break down crystal violet dye. To comprehend the impact of three variables—pH, time, and SeNP concentration—on the dye degradation, a full factorial design was employed. This study showed that SeNPs can be used as a potential anti‐biofilm agent and are also effective in the textile, dye, and pharmaceutical industries.
Attractors of a thermoelastic Bresse system with mass diffusion
Authors: Li Haiyan , Cabanillas Victor R. , Feng Baowei 
Published: August 2024

AbstractThis paper concerns the long‐time dynamics of a thermoelastic Bresse system with mass diffusion. We prove the existence of a global attractor by showing that the system is gradient and asymptotically smooth. In addition, the attractor is characterized as an unstable manifold of the set of stationary solutions. The quasi‐stability of the system and the finite fractal dimension of the global attractor are established by a stabilizability inequality. Finally, we prove the upper semicontinuity of the global attractor regarding the parameter in a dense residual set.
Override and restricted union for partial functions
Authors: Stokes Tim 
Published: August 2024

AbstractThe override operation $$\sqcup $$
⊔
is a natural one in computer science, and has connections with other areas of mathematics such as hyperplane arrangements. For arbitrary functions f and g, $$f\sqcup g$$

f
⊔
g

is the function with domain $${{\,\textrm{dom}\,}}(f)\cup {{\,\textrm{dom}\,}}(g)$$

dom

(
f
)
∪

dom

(
g
)

that agrees with f on $${{\,\textrm{dom}\,}}(f)$$

dom

(
f
)

and with g on $${{\,\textrm{dom}\,}}(g) \backslash {{\,\textrm{dom}\,}}(f)$$

dom

(
g
)
\

dom

(
f
)

. Jackson and the author have shown that there is no finite axiomatisation of algebras of functions of signature $$(\sqcup )$$

(
⊔
)

. But adding operations (such as update) to this minimal signature can lead to finite axiomatisations. For the functional signature $$(\sqcup ,\backslash )$$

(
⊔
,
\
)

where $$\backslash $$
\
is set-theoretic difference, Cirulis has given a finite equational axiomatisation as subtraction o-semilattices. Define $$f\curlyvee g=(f\sqcup g)\cap (g\sqcup f)$$

f
⋎
g
=
(
f
⊔
g
)
∩
(
g
⊔
f
)

for all functions f and g; this is the largest domain restriction of the binary relation $$f\cup g$$

f
∪
g

that gives a partial function. Now $$f\cap g=f\backslash (f\backslash g)$$

f
∩
g
=
f
\
(
f
\
g
)

and $$f\sqcup g=f\curlyvee (f\curlyvee g)$$

f
⊔
g
=
f
⋎
(
f
⋎
g
)

for all functions f, g, so the signatures $$(\curlyvee )$$

(
⋎
)

and $$(\sqcup ,\cap )$$

(
⊔
,
∩
)

are both intermediate between $$(\sqcup )$$

(
⊔
)

and $$(\sqcup ,\backslash )$$

(
⊔
,
\
)

in expressive power. We show that each is finitely axiomatised, with the former giving a proper quasivariety and the latter the variety of associative distributive o-semilattices in the sense of Cirulis.
Exosomes derived from BMSCs in osteogenic differentiation promote type H blood vessel angiogenesis through miR-150-5p mediated metabolic reprogramming of endothelial cells
Authors: Wu Feng , Song Chengchao , Zhen Guanqi , Jin Qin , Li Wei , Liang Xiongjie , Xu Wenbo , Guo Wenhui , Yang Yang , Dong Wei , Jiang Anlong , Kong Pengyu , Yan Jinglong 
Published: August 2024

AbstractOsteogenesis is tightly coupled with angiogenesis spatiotemporally. Previous studies have demonstrated that type H blood vessel formed by endothelial cells with high expression of CD31 and Emcn (CD31hi Emcnhi ECs) play a crucial role in bone regeneration. The mechanism of the molecular communication around CD31hi Emcnhi ECs and bone mesenchymal stem cells (BMSCs) in the osteogenic microenvironment is unclear. This study indicates that exosomes from bone mesenchymal stem cells with 7 days osteogenic differentiation (7D-BMSCs-exo) may promote CD31hi Emcnhi ECs angiogenesis, which was verified by tube formation assay, qRT-PCR, Western blot, immunofluorescence staining and µCT assays etc. in vitro and in vivo. Furthermore, by exosomal miRNA microarray and WGCNA assays, we identified downregulated miR-150-5p as the most relative hub gene coupling osteogenic differentiation and type H blood vessel angiogenesis. With bioinformatics assays, dual luciferase reporter experiments, qRT-PCR and Western blot assays, SOX2(SRY-Box Transcription Factor 2) was confirmed as a novel downstream target gene of miR-150-5p in exosomes, which might be a pivotal mechanism regulating CD31hi Emcnhi ECs formation. Additionally, JC-1 immunofluorescence staining, Western blot and seahorse assay results showed that the overexpression of SOX2 could shift metabolic reprogramming from oxidative phosphorylation (OXPHOS) to glycolysis to enhance the CD31hi Emcnhi ECs formation. The PI3k/Akt signaling pathway might play a key role in this process. In summary, BMSCs in osteogenic differentiation might secrete exosomes with low miR-150-5p expression to induce type H blood vessel formation by mediating SOX2 overexpression in ECs. These findings might reveal a molecular mechanism of osteogenesis coupled with type H blood vessel angiogenesis in the osteogenic microenvironment and provide a new therapeutic target or cell-free remedy for osteogenesis impaired diseases.
Alx3 deficiency disrupts energy homeostasis, alters body composition, and impairs hypothalamic regulation of food intake
Authors: Mirasierra Mercedes , Fernández-Pérez Antonio , Lizarbe Blanca , Keiran Noelia , Ruiz-Cañas Laura , Casarejos María José , Cerdán Sebastián , Vendrell Joan , Fernández-Veledo Sonia , Vallejo Mario 
Published: August 2024

AbstractThe coordination of food intake, energy storage, and expenditure involves complex interactions between hypothalamic neurons and peripheral tissues including pancreatic islets, adipocytes, muscle, and liver. Previous research shows that deficiency of the transcription factor Alx3 alters pancreatic islet-dependent glucose homeostasis. In this study we carried out a comprehensive assessment of metabolic alterations in Alx3 deficiency. We report that Alx3-deficient mice exhibit decreased food intake without changes in body weight, along with reduced energy expenditure and altered respiratory exchange ratio. Magnetic resonance imaging reveals increased adiposity and decreased muscle mass, which was associated with markers of motor and sympathetic denervation. By contrast, Alx3-deficient mice on a high-fat diet show attenuated weight gain and improved insulin sensitivity, compared to control mice. Gene expression analysis demonstrates altered lipogenic and lipolytic gene profiles. In wild type mice Alx3 is expressed in hypothalamic arcuate nucleus neurons, but not in major peripheral metabolic organs. Functional diffusion-weighted magnetic resonance imaging reveals selective hypothalamic responses to fasting in the arcuate nucleus of Alx3-deficient mice. Additionally, altered expression of proopiomelanocortin and melanocortin-3 receptor mRNA in the hypothalamus suggests impaired regulation of feeding behavior. This study highlights the crucial role for Alx3 in governing food intake, energy homeostasis, and metabolic nutrient partitioning, thereby influencing body mass composition.