bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Microwave‐Promoted Copper‐Free Sonogashira—Hagihara Couplings of Aryl Imidazolylsulfonates in Water.
Authors: Civicos Jose F. , Alonso Diego A. , Najera Carmen 
Published: May 2013

AbstractA number of disubstituted alkynes are synthesized in good to high yields by the presented new method under microwave irradiation within short reaction times.
ChemInform Abstract: Facile Synthesis of Novel Bicyclic β‐Lactams: Analogues of C‐Fused Penicillin Type Ring Systems.
Authors: Bari S. S. , Bhalla Aman , Reshma Reshma , Hundal Geeta 
Published: May 2013

AbstractPOCl3‐promoted cyclocondensation of mercaptoacetic acids and unsaturated imines offers cis/trans mixtures of β‐lactams.
ChemInform Abstract: Transesterification of Trimethyl Orthoacetate: An Efficient Protocol for the Synthesis of 4‐Alkoxy‐2‐aminothiophene‐3‐carbonitriles.
Authors: Rao K. Venkata , Balakumar C. , Narayana B. Lakshmi , Kishore D. Pran , Rajwinder K. , Rao A. Raghuram 
Published: May 2013

AbstractA facile protocol for the synthesis of functionalized title compounds (IV) (16 examples) involves transesterification of substrates with higher alcohols, subsequent reaction with dinitrile and final Gewald reaction.
ChemInform Abstract: A Stereoselective Cyclization Strategy for the Preparation of γ‐Lactams and Their Use in the Synthesis of α‐Methyl‐β‐proline.
Authors: Banerjee Souvik , Smith Justin , Smith Jillian , Faulkner Caleb , Masterson Douglas S. 
Published: May 2013

AbstractThe reaction of benzyl malonic esters with hydrazine allows a convenient and stereoselective access to the (R)‐γ‐lactam (IV).
ChemInform Abstract: Synthesis of 2‐Phenyl‐4,5‐Substituted Oxazoles by Copper‐Catalyzed Intramolecular Cyclization of Functionalized Enamides.
Authors: Kumar S. Vijay , Saraiah B. , Misra N. C. , Ila H. 
Published: May 2013

AbstractRegioselective ring opening of oxazolones of type (IV) [inter alia precursors of aminocarboxylic acids (II)] by diverse nucleophiles followed by Cu‐catalyzed ring closure of resulting enamides provides an efficient approach to various 2‐phenyl‐4,5‐substituted oxazoles.
ChemInform Abstract: Synthesis of 5‐Aryl‐3H‐[1,3,4]oxadiazol‐2‐ones from N′‐(Chloro‐aryl‐methylene)‐tert‐butylcarbazates Using Basic Alumina as an Efficient and Recyclable Surface under Solvent‐Free Condition.
Authors: Debnath Kamalesh , Pathak Sudipta , Pramanik Animesh 
Published: May 2013

AbstractThe method is advantageous with regard to short reaction times, operational simplicity, and reusability of the solid support.
ChemInform Abstract: Construction of Multisubstituted Tetrahydropyrans by a Domino Oxa‐Michael/Tsuji—Trost Reaction.
Authors: Wang Liang , Menche Dirk 
Published: May 2013

AbstractPd‐catalyzed treatment of unsaturated alcohols of type (I) with nitro olefins provides a new and efficient approach to multisubstituted tetrahydropyrans, which are of synthetic and biological interest.
ChemInform Abstract: Efficient and Chemoselective Reduction of Pyridines to Tetrahydropyridines and Piperidines via Rhodium‐Catalyzed Transfer Hydrogenation.
Authors: Wu Jianjun , Tang Weijun , Pettman Alan , Xiao Jianliang 
Published: May 2013

AbstractA simple and efficient protocol for the chemoselective reduction of pyridinium salts in excellent yields using low catalyst loadings is shown.
ChemInform Abstract: Silica‐Supported Tungstic Acid (STA): An Efficient Catalyst for the Synthesis of Bis‐Spiro Piperidine Derivatives under Milder Conditions.
Authors: Atar Amol B. , Jeong Yeon Tae 
Published: May 2013

AbstractThe process uses dimedone, aromatic amines, and formaldehyde as raw materials to form the title system with simple work‐up and easy recovery of the heterogeneous catalyst.
ChemInform Abstract: Catalytic Enantioselective Synthesis of Atropisomeric 2‐Aryl‐4‐quinolinone Derivatives with an N—C Chiral Axis.
Authors: Takahashi Isao , Morita Fumika , Kusagaya Shunsuke , Fukaya Haruhiko , Kitagawa Osamu 
Published: May 2013

AbstractThe 1,4‐addition of aniline (II) to ynones (I) and (IV) followed by intramolecular Buchwald—Hartwig amination affords axially chiral quinoline derivatives (III) and (V).
ChemInform Abstract: Efficient Synthesis and X‐Ray Structures of New α‐Quinolin‐3‐yl‐α‐aminonitriles and Derivatives.
Authors: Ladraa Souheila , Berree Fabienne , Bouraiou Abdelmalek , Bouacida Sofiane , Roisnel Thierry , Carboni Bertrand , Belfaitah Ali 
Published: May 2013

AbstractTreatment of various aldimine substrates, readily prepared from the corresponding aldehydes, with nitrile (II) affords the desired title compounds as a combination of biologically important quinoline units and α‐amino acids.
ChemInform Abstract: Three‐Component, One‐Pot Sequential Synthesis of Functionalized Cyclazines: 3H‐1,2a1,3‐Triazaacenaphthylenes.
Authors: Shen Jingkang , et al. et al. 
Published: May 2013

AbstractAn efficient and widely applicable method to prepare new triazaacenaphthylenes as well as tetraazaacenaphthylenes is reported.
ChemInform Abstract: Synthesis of Quinazolin‐4(3H)‐ones via Amidine N‐Arylation.
Authors: Li Bryan , Samp Lacey , Sagal John , Hayward Cheryl M. , Yang Christine , Zhang Zhijun 
Published: May 2013

AbstractA high throughput route towards the orally active calcium‐sensing receptor antagonist (XIIIb) is developed.
ChemInform Abstract: Copper(I)‐Catalyzed [3 + 2] Cycloaddition/Ring‐Opening Rearrangement/[4 + 2] Cycloaddition/Aromatization Cascade: An Unprecedented Chemo‐ and Stereoselective Three Component Coupling of Sulfonyl Azide, Alkyne and N‐Arylidenepyridin‐2‐amine to Pyrido[1,2‐a]pyrimidin‐4‐imine.
Authors: Namitharan Kayambu , Pitchumani Kasi 
Published: May 2013

AbstractAn efficient, simple and new protocol for the synthesis of N‐substituted pyrido[1,2‐a]pyrimidin‐4‐imine derivatives [cf.
ChemInform Abstract: Straightforward Access to Enantioenriched Pyrazyl Alcohols Using Chiral Organomagnesiates.
Authors: Payen Olivier , Chevallier Floris , Mongin Florence , Gros Philippe C. 
Published: May 2013

AbstractThe iodine‐magnesium exchange of iodopyrazine (I) and subsequent enantioselective addition of the intermediate magnesiate to aldehydes (II) using ((R,R)‐TADDOLate)Bu2MgLi2 is described.
ChemInform Abstract: A Simple One‐Pot Method for the Mercuric Oxide Mediated Synthesis of Piperazines via Oxidative Diamination of Olefins.
Authors: Kour Harpreet , Paul Satya , Singh Parvinder Pal , Gupta Monika , Gupta Rajive 
Published: May 2013

AbstractUnder optimized conditions including preformed HgO·2HBF4, the reaction of olefins with N‐protected ethylene diamine gives piperazine products.
ChemInform Abstract: Disiloxanes with Cyclic or Non‐Cyclic Carbamate Moieties as Electrolytes for Lithium‐Ion Batteries.
Authors: Jeschke Steffen , Gentschev Ann‐Christin , Wiemhoefer Hans‐Dieter 
Published: May 2013

AbstractThe synthesis, ionic conductivity, thermal properties, viscosity, and relative permittivity of four liquid disiloxanes are reported.
ChemInform Abstract: Regio‐ and Stereoselective Preparation of (Z)‐Silyl Enol Ethers by Three‐Component Coupling Using α,β‐Unsaturated Acylsilanes as Core Building Blocks.
Authors: Tsubouchi Akira , Sasaki Natsuki , Enatsu Shouko , Takeda Takeshi 
Published: May 2013

AbstractReaction of α,β‐unsaturated acylsilanes (I) with alkyl metal reagents followed by CuOtBu and allylic chlorides (II) provides the title compounds in a stereoselective manner.
ChemInform Abstract: A One‐Pot, Copper‐Catalyzed Cascade Route to 2‐Indolyl‐C‐glycosides.
Authors: Subramanian Parthasarathi , Kaliappan Krishna P. 
Published: May 2013

AbstractAn efficient synthesis of a variety of N‐tosyl‐2‐C‐glycosides is accomplished through a cascade reaction of C‐alkynyl glycosides that involves a sequential Sonogashira type coupling and cyclative‐hydroamination.
ChemInform Abstract: Imaging Catalysts at Work: A Hierarchical Approach from the Macro‐ to the Meso‐ and Nano‐Scale
Authors: Grunwaldt Jan‐Dierk , Wagner Jakob B. , Dunin‐Borkowski Rafael E. 
Published: May 2013

AbstractReview: prospects for the development and combined application of existing and new techniques for in situ catalyst characterization; 125 refs.
The Helmholtz Energy Alliance “Energy Efficient Multiphase Chemical Processes”
Authors: Hampel Uwe , Dittmeyer Roland , Patyk Andreas , Wetzel Thomas , Lange Rüdiger , Freund Hannsjörg , Schwieger Wilhelm , Grünewald Marcus , Schlüter Michael , Petasch Uwe 
Published: May 2013

AbstractEnergieeffizienz ist ein wesentlicher Baustein nachhaltigen Wirtschaftens und unabdingbare Voraussetzung zur Erreichung aktueller klimapolitischer Ziele. Die von der Helmholtz‐Gemeinschaft Deutscher Forschungszentren geförderte Energie‐Allianz „Energieeffiziente chemische Mehrphasenprozesse”︁ bündelt Kompetenzen und Forschungsaktivitäten im Bereich der chemischen Verfahrenstechnik mit dem Ziel der Weiterentwicklung von Entwurfs‐ und Auslegungsmethoden, numerischen und experimentellen Techniken sowie neuer Messeverfahren zur Effizienzsteigerung chemischer Mehrphasenprozesse.
Is There BN Bond‐Length Alternation in 1,2:3,4:5,6‐Tris(biphenylylene)borazines?
Authors: Müller Matthias , Maichle‐Mössmer Cäcilia , Sirsch Peter , Bettinger Holger F. 
Published: May 2013

AbstractThe alternation of the BN bonds in the central borazine ring of the overcrowded 1,2:3,4:5,6‐tris(biphenylylene)borazine (2 a) and its tribromo derivative (2 g) is investigated by computational methods and compared with their experimentally obtained crystal structures. The calculations are performed with a meta‐generalized‐gradient‐approximation (GGA) density functional (Tao–Perdew–Staroverov–Scuseria (TPSS)) without and with dispersion corrections, including Becke–Johnson damping, in conjunction with a polarized triple‐ζ basis set. These data show a small bond‐length alternation (BLA) of around 0.01 Å in 2 a and 2 g. This outcome is in good agreement with X‐ray diffraction data for 2 g, but at variance with earlier X‐ray diffraction measurements that gave a BLA of 0.06 Å for 2 a. A re‐investigation of the crystal structure of 2 a reveals a positional disorder that precludes a discussion of the BN bond lengths. The synthesis of 2 g is the first example of an electrophilic aromatic substitution of an aryl borazine with elemental bromine. Successful bromination was also demonstrated for hexaphenylborazine.
A proposed complementary pairing mode between single‐stranded nucleic acids and β‐stranded peptides: A possible pathway for generating complex biological molecules
Authors: Zhang Shuguang , Egli Martin 
Published: May 2013

AbstractA structure for a heterologous double‐stranded molecule consisting of an oligoribonucleotide and a β‐stranded oligopeptide, paired through complementary Watson‐Crick‐type hydrogen bonding, is proposed. The basis for such complementary pairings between oligoribonucleotides and oligopeptides is the close correspondence of the distances between the side‐chains attached to the backbones of the two molecules. Both inter‐nucleotide spacing and inter‐amino acid side‐chain spacing are approximately 3.4 Å. These kinds of interactions may have implications in protein‐mediated‐RNA splicing. Formation of a heterologous duplex through such a pairing mode could provide a simple coding mechanism for a reciprocal information transfer between oligonucleotides and oligopeptides. Because of its simplicity and versatility, allowing both specific and nonspecific coding, interactions via these kinds of pairing may have been relevant for prebiotic molecular evolution and for generating complex biological molecules.
Complex systems in drug research: I. The chemical levels
Authors: Testa Bernard , Kier Lemont B. 
Published: May 2013

AbstractThe hierarchy of chemical systems is examined. It is argued that an intermediate level of complexity, that of functional groups, exists between atoms and molecules. Molecular properties have an emergent nature, e.g., the “chameleonic behavior.” Aggregates of molecules and solutions also behave as complex systems. Emergent properties are particularly noteworthy in biological macromolecules and correspond to basins of attraction resulting from a complex interplay between intramolecular and intermolecular interactions.
Atomic Layer Deposition of Al‐doped ZnO Films Using Aluminum Isopropoxide as the Al Precursor
Authors: Qian Xu , Cao Yanqiang , Guo Binglei , Zhai Haifa , Li Aidong 
Published: May 2013

AbstractAl‐doped ZnO (AZO) films are deposited at 200°C by atomic layer deposition (ALD) on borosilicate glass and Si(001) substrates using diethylzinc (DEZ) and aluminum isopropoxide (AIP) as the Zn and Al precursors, respectively. The effect of the Zn/Al ALD cycle ratio and the AIP source temperature on the Al dopant concentration and resistivity of AZO films is carefully investigated. By changing the AIP temperature from 115°C to 135°C, at the optimal Zn/Al cycle ratio of 19:1, the Al dopant concentration ([Al]/([Al] + [Zn])) in AZO films varies from 0.15 at.‐% to 2.32 at.‐%. The 60 nm thick AZO films deposited at an AIP temperature of 120°C show the lowest resistivity of 9.4 × 10−4 Ω cm, with better optical transparency.
(Pyrenetetrasulfonate/ZnS)n Ordered Ultrathin Films with ZnAl Layered Double Hydroxide as Precursor and Ethanol‐Sensing Properties
Authors: Xiao Ya‐Ping , Zhang Li‐Min , Guo Ying , Song Yu‐Fei 
Published: May 2013

AbstractWell‐ordered ultrathin films (UTFs) of {pyrenetetrasulfonate(PyTS)/ZnS}n were fabricated by alternating assembly of 1,3,6,8‐PyTS and exfoliated Zn2Al layered double hydroxide (LDH) nanosheets through layer‐by‐layer (LBL) electrostatic deposition, followed by an effective in situ gas/solid sulfurization reaction with H2S. The assembly process was monitored by UV/Vis spectroscopy, which showed regular stepwise growth of the (PyTS/LDH)n UTFs with consecutive deposition cycles. It is worth noting that the structure of the well‐ordered UTFs is retained after the in situ gas/solid sulfurization reaction. Although both (PyTS/LDH)n UTFs and the sulfurized (PyTS/ZnS)n UTFs respond to ethanol at a relatively low operating temperature (70 °C), the (PyTS/ZnS)n UTFs exhibit a much better response, a fact that can be attributed to synergistic interactions between inorganic ZnS and organic pyrene components. Moreover, the well‐ordered (PyTS/ZnS)30 UTF exhibits a stronger sensor response to ethanol than to other gases, including NH3, H2, CO, C2H2, and CH4.
4,4″‐Disubstituted Terpyridines and Their Homoleptic FeII Complexes
Authors: Harzmann Gero D. , Neuburger Markus , Mayor Marcel 
Published: May 2013

AbstractA novel synthetic route to 4,4″‐disubstituted‐2,2′:6′,2″‐terpyridine ligands by Suzuki–Miyaura cross‐coupling was elaborated by synthesizing compounds 4a–5c. The considerable stability of 4‐substituted lithium triisopropyl 2‐pyridylborates 2a–c, which are less prone to protodeboronation than similarly functionalized neutral boronic acid derivatives, enabled this synthetic route. The terpyridine core structure was further functionalized by exposing 4,4″‐dichloroterpyridine (4b) to Suzuki coupling conditions to yield 4,4″‐diarylterpyridines 5a–c. Homoleptic FeII complexes 8a–f of the reported terpyridine ligands were formed quantitatively, which demonstrates the lack of steric repulsion of substituents at the 4‐ and 4″‐positions during complexation. The solid‐state structures of particular ligands and FeII complexes were analyzed by single‐crystal X‐ray crystallography. UV/Vis absorption data for the FeII complexes are also provided to complement the results reported here.
One‐Pot Three‐Component Heteroannulation of β‐Oxo Dithioesters, Amines and Hydroxylamine: Regioselective, Facile and Straightforward Entry to 5‐Substituted 3‐Aminoisoxazoles
Authors: Samai Subhasis , Chanda Tanmoy , Ila Hiriyakkanavar , Singh Maya Shankar 
Published: May 2013

AbstractAn efficient and highly regioselective one‐pot three‐component synthesis of previously inaccessible and synthetically demanding 3‐(cycloalkyl/alkyl/arylamino)‐5‐aryl/alkylisoxazoles has been achieved by the cyclocondensation of β‐oxo dithioesters, amines and hydroxylamine in ethanol at reflux. This transformation proceeds via an in situ generated β‐oxothioamide by the reaction of the β‐oxo dithioester and amine, which undergoes nucleophilic attack by hydroxylamine followed by intramolecular cyclization with the oxo functionality and subsequent dehydration to give 5‐substituted 3‐aminoisoxazoles as a single regioisomer in good yields. Furthermore, the mechanism of the reaction has been established experimentally and shown to be in agreement with the hard and soft (Lewis) acid and base (HSAB) theory.
Access to Imidazo[1,2‐a]imidazolin‐2‐ones and Functionalization through Suzuki–­Miyaura Cross‐Coupling Reactions
Authors: Grosse Sandrine , Pillard Christelle , Himbert Franck , Massip Stéphane , Léger Jean Michel , Jarry Christian , Bernard Philippe , Guillaumet Gérald 
Published: May 2013

AbstractWe report herein a synthetic pathway to new 6(5)‐bromo‐5(6)‐methylimidazo[1,2‐a]imidazolin‐2‐ones. The synthetic potential of these scaffolds was demonstrated by displacing bromine by Suzuki–Miyaura cross‐coupling reactions. A large panel of boronic acids (aryl, heteroaryl or vinyl) could easily be introduced, giving access to a large and diversified library of 6(5)‐substituted 5(6)‐methylimidazo[1,2‐a]imidazolin‐2‐ones.
The Use of Guided Self‐help Incorporating a Mobile Component in People with Eating Disorders: A Pilot Study
Authors: Cardi Valentina , Clarke Ariana , Treasure Janet 
Published: May 2013

AbstractObjectiveThe aim of this pilot study was to test the acceptability and benefit of a guided self‐help intervention incorporating a mobile component in eating disorders (EDs).MethodEighteen people with Anorexia Nervosa and eleven people with Bulimia Nervosa were included in the study for 3 weeks and self‐report and behavioural assessments were made before and after the intervention which included 10 video clips, a manual, and limited guidance.ResultsThe most reported positive comment associated with the use of the vodcasts was the increased awareness about the illness. Adherence was good (29/31 subjects completed). A medium sized increase in Body Mass Index was found in participants with Anorexia Nervosa, and significantly lowered EDs and mood symptoms (effect size range = 0.72/1.35), and improvement in cognitive flexibility were reported post‐intervention.DiscussionA guided self‐help intervention incorporating a mobile component was both acceptable and associated with symptom change in people with EDs. Copyright © 2013 John Wiley & Sons, Ltd and Eating Disorders Association.
Tight upper bounds on average detection probability in cooperative relay networks with selection combiner
Authors: Mughal M.O. , Razi A. , Kim J.M. 
Published: May 2013

AbstractIn this study, the detection probability for amplify–forward‐based cooperative relay networks, where the destination is equipped with a selection combiner and energy detector, is analysed. The probability density function method and an alternative series representation of the generalized Marcum‐Q function are used to obtain two upper bounds for the average detection probability. The error bounds resulting from truncating an infinite summation series to finite terms are also calculated because the derived expressions were in the form of an infinite summation series. Finally, the analysis are validated by simulations. These results are expected to assist in future studies of communication technologies, such as cognitive radios. Copyright © 2013 John Wiley & Sons, Ltd.
Performance analysis of dual‐hop MIMO AF relay systems with MIMO‐MRC in the presence of co‐channel interferences
Authors: Xu X. , Cai Y. , Yang W. 
Published: May 2013

AbstractThe performance of dual‐hop multiple‐input multiple‐output relay systems with transmit beamforming and maximum‐ratio combining scheme for each hop is investigated. Both the relay and the destination are subjected to multiple possible unequal‐power co‐channel interferences (CCIs). We provide a mathematical framework for evaluating the combined effect of multiple antennas and CCIs. An exact closed‐form outage probability expression is derived for the independent Rayleigh fading channels. Furthermore, the asymptotic analysis for the outage probability is also presented to offer more insights into the system diversity order. The results show that although the diversity order is limited by the minimum of the numbers of antennas at the source and the destination, it is essentially directly proportional to the number of antennas at the relay, which provides a further insight into the system design. Moreover, at high signal‐to‐interference ratio regime, CCIs do not affect the diversity order.Copyright © 2013 John Wiley & Sons, Ltd.
Two‐dimensional two‐layer shallow water model for dam break flows with significant bed load transport
Authors: Swartenbroekx Catherine , Zech Yves , Soares‐Frazão Sandra 
Published: May 2013

SUMMARYRiver flow dynamics and sediment transport are intimately interdependent. Their interaction governs a great diversity of flows with significant morphologic consequences. To predict the bed load transport induced by dam break waves, the proposed two‐dimensional (2D) two‐layer shallow water description considers an upper layer made of clear water and a lower layer made of a dense mixture of water and moving grains. Continuity and 2D momentum conservation are written for each layer, which allows the depth‐averaged velocities to be distinct in magnitude and direction in both layers. The model accounts for the grain entrainment across the bed interface and for the mass and momentum exchanges between the flowing layers. The system of governing equations, written so that no loss of hyperbolicity occurs in the conservative part, is solved by a Harten–Lax–Van Leer finite volume scheme on an unstructured triangular mesh. The numerical model is tested against four dam break flows over mobile beds: a theoretical radial problem and three laboratory experiments in 1D and 2D configurations. Copyright © 2013 John Wiley & Sons, Ltd.
THE MOTIVES OF INTERGENERATIONAL TRANSFER TO THE ELDERLY PARENTS IN CHINA: CONSEQUENCES OF HIGH MEDICAL EXPENDITURE
Authors: Wu Xiaoyu , Li Lixing 
Published: May 2013

ABSTRACTThe support for the elderly is facing big challenges with the problem of population aging. Transfers from adult children could partly insure elderly parents against low income and high medical expenditure. There are two main motives for transfers in the literature, namely altruism and exchange. By using data from a new household survey of people aged 45 years and above in China, we estimate the transfer derivatives with the adjustment of medical expenditure in elderly parents' income. We find a large negative impact of adjusted income on transfers at the lower end of income distribution, which is consistent with the altruistic motive. Evidence on the exchange motive is found only for sons, but not for daughters. In addition, there is evidence on the ‘exchange‐for‐service’ motive, which interprets transfer as a payment to parents' family services, such as taking care of grandchildren. Copyright © 2013 John Wiley & Sons, Ltd.
Efficient Synthesis of 1‐Arylquinoxalin‐2(1H)‐ones via Cyclocondensation of N‐Aryl‐Substituted 2‐Nitrosoanilines with Functionalized Alkyl Acetates
Authors: Wróbel Zbigniew , Stachowska Karolina , Kwast Andrzej , Gościk Agata , Królikiewicz Magdalena , Pawłowski Robert , Turska Izabela 
Published: May 2013

AbstractN‐Aryl‐substituted 2‐nitrosoanilines (=2‐nitrosobenzenamines) 1, readily available by nucleophilic substitution of the ortho‐H‐atom in nitroarenes with arenamines, react with 2‐substituted acetic acid esters in the presence of a weak base giving 1‐arylquinoxalin‐2(1H)‐ones (Scheme 2). This cyclocondensation allows for the synthesis of compounds 2–4, unsubstituted at C(3) or substituted by alkyl, aryl, ester, amide, and keto groups, in good to excellent yields (Tables 1–4).