bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pharmacokinetics of meloxicam in rabbits after oral administration of single and multiple doses
Authors: Fredholm Daniel V. , Carpenter James W. , KuKanich Butch , Kohles Micah 
Published: March 2013

Abstract
Objective—To determine the pharmacokinetics of meloxicam (1 mg/kg) in rabbits after oral administration of single and multiple doses.
Animals—6 healthy rabbits.
Procedures—A single dose of meloxicam (1 mg/kg, PO) was administered to the rabbits. After a 10-day washout period, meloxicam (1 mg/kg, PO) was administered to rabbits every 24 hours for 5 days. Blood samples were obtained from rabbits at predetermined intervals during both treatment periods. Plasma meloxicam concentrations were determined, and noncompartmental pharmacokinetic analysis was performed.
Results—The mean peak plasma concentration and area under the plasma concentration-versus-time curve extrapolated to infinity after administration of a single dose of meloxicam were 0.83 μg/mL and 10.37 h•μg/mL, respectively. After administration of meloxicam for 5 days, the mean peak plasma concentration was 1.33 μg/mL, and the area under the plasma concentration-versus-time curve from the time of administration of the last dose to 24 hours after that time was 18.79 h•μg/mL. For single- and multiple-dose meloxicam experiments, the mean time to maximum plasma concentration was 6.5 and 5.8 hours and the mean terminal half-life was 6.1 and 6.7 hours, respectively.
Conclusions and Clinical Relevance—Plasma concentrations of meloxicam for rabbits in the present study were proportionally higher than those previously reported for rabbits receiving 0.2 mg of meloxicam/kg and were similar to those determined for animals of other species that received clinically effective doses. A dose of 1 mg/kg may be necessary to achieve clinically effective circulating concentrations of meloxicam in rabbits, although further studies are needed.
Evaluation of glomerular filtration rate in cats with reduced renal mass and administered meloxicam and acetylsalicylic acid
Authors: Surdyk Kathryn K. , Brown Cathy A. , Brown Scott A. 
Published: March 2013

Abstract
Objective—To determine whether administration of meloxicam or acetylsalicylic acid alters glomerular filtration rate (GFR) in cats with renal azotemia.
Animals—6 young adult cats.
Procedures—3 sexually intact male cats and 3 sexually intact female cats had surgically reduced renal mass and azotemia comparable to International Renal Interest Society chronic kidney disease stages 2 and 3. Renal function was evaluated by measurement of serum creatinine concentration, urinary clearance of exogenously administered creatinine, and the urine protein-to-creatinine concentration ratio (UP:C). Measurements taken in cats receiving placebo at the beginning and end of the study were compared with results obtained at the end of 7 days of treatment with either meloxicam (0.2 mg/kg, SC, on day 1; 0.1 mg/kg, SC, on days 2 to 7) or acetylsalicylic acid (20 mg/kg, PO, on days 1, 4, and 7).
Results—No significant treatment effects on urinary clearance of exogenously administered creatinine, serum creatinine concentration, or UP:C were detected. Mean ± SEM serum creatinine concentration and urinary clearance of exogenously administered creatinine measurements following 7 days of treatment with meloxicam (serum creatinine concentration, 2.67 ± 0.17 mg/dL; urinary clearance of exogenously administered creatinine, 1.34 ± 0.08 mL/min/kg) and acetylsalicylic acid (serum creatinine concentration, 2.62 ± 0.12 mg/dL; urinary clearance of exogenously administered creatinine, 1.35 ± 0.07 mL/min/kg) were not significantly different from the mean baseline values for these variables (serum creatinine concentration, 2.77 ± 0.14 mg/dL; urinary clearance of exogenously administered creatinine, 1.36 ± 0.07 mL/min/kg).
Conclusions and Clinical Relevance—Neither meloxicam nor acetylsalicylic acid had a measurable effect on urinary clearance of exogenously administered creatinine, serum creatinine concentration, or UP:C. These results are consistent with the hypothesis that GFR of euvolemic cats with normal or reduced renal function is not dependent on cyclooxygenase function.
The long and winding road to publication
Authors: Van Teijlingen Edwin Roland , Simkhada Padam Prasad , Simkhada Bibha , Ireland Jillian Catherine 
Published: March 2013

It is clear that academic dissemination has a system of checks and balances which authors may experience as barriers. We all want to be sure that scientific information disseminated in academic journals is based on solid data, ethically collected and correctly interpreted. The process of peer reviewing helps to prevent bad science and/or poor scientific papers being published. Many published scientific papers differ from the original submitted manuscript since papers go through a process of peer-review, editing and rewriting. However, there are other potential obstacles in the field of academic publishing. This paper is a case-study of one methods paper which stumbled upon a number of barriers related to the viability and continued existence of a number of academic journals in Nepal. Finally, we offer some advice to help health journals to survive when their editors leave.DOI: http://dx.doi.org/10.3126/nje.v2i4.7093Nepal Journal of Epidemiology Vol.2(4) 2012 pp.213-215
Book Reviews
Authors: McIntire C. , Hayes Alan , Gollnick James , Vertin Michael , Kahn Abrahim , Wiebe Dona;d , Schafer Stephen , Neelands David 
Published: March 2013

John Van Seters, In Search of History: Historiography in the Ancient World and the Origins of Biblical History, reviewed by C.T. McIntire Ernest E. Best, Religion and Society in Transition: The Church and Social Change in England, 1560-1850reviewed by Alan L. Hayes John Heaney, The Sacred and the Psychic, reviewed by James T. Gollnick Bernard Lonergan, Ritual Magic, reviewed by Michael Vertin Grace Jantzen, God's World, God's Body, reviewed by Abrahim H. Khan J. Habermas, The Theory of Communicative Action, Vol. 1, The Rationalization of Society, reviewed by Donald Wiebe Helmut Peukert, Science, Action, and Fundamental Theology: Toward a Theology of Communicative Action, reviewed by Stephen J. Schafer M. Darrol Bryant, ed., The Future of Anglican Theologyreviewed by W. David Neelands
The Nixon-Cronin Speeches: A Cold War Theology
Authors: O'brien Thomas 
Published: March 2013

My purpose here is to uncover and examine a theology that is sometimes explicit, but more often implied, in Richard Nixon's speeches delivered between 1953 and 1960, the original texts of which were written by a Roman Catholic priest, John F. Cronin. First I will survey the history of the association between Cronin and Nixon. Second, I will deal with the speeches themselves and the theology that often lay just beneath the surface. Finally, I will look at the practical consequences of this Cold War theology and the mission entrusted to its believers. The questions arising from this sort of study are legion. Given the history of American suspicion in regard to Roman Catholics, how did a Roman Catholic priest acquire such an influential position among early Cold War theorists- especially with Richard Nixon, a Quaker? Do Nixon's speeches presuppose a theological interpretation of world events? Is the Cold War theology of the speeches a genuinely Christian theology, or is it a form of idolatry?
The Local Church in a Multicultural Society: An Orthodox Solution for an Unorthodox Dilemma
Authors: Smith T. 
Published: March 2013

The Orthodox Church in Canada finds itself in an ecclesiological dilemma on the eve of its second century of presence in this part of the world. For a variety of sociological and theological reasons, it has thus far been unable to coalesce into one visible institution, remaining instead segregated along ethnopolitical lines and showing few signs of escaping from its resultant selfimposed marginalization in Canadian society. The widely respected and well received theology of the local church as the preferred Orthodox insight into the nature and functioning of Christian community has thus far made little headway in extricating Orthodox Christianity in the Canadian context from its chaotic jurisdictional status. The reality of multiculturalism as a distinguishing characteristic of Canadian society further complicates the issue by offering a secularized model of the Pentecost event as a powerful extra-ecclesial argument for the retention of ethnically defined churches. For the outside admirer of Eastern Christianity, this ongoing failure of the Orthodox to address the problems confronting their church in a multicultural society runs the risk of eliminating by neglect an incarnation of the Christian experience of God of immense value for all Christian traditions. It is to commit on a theological level the same fundamental error which on a sociological level plagues the establishment of multiculturalism in Canada: to ignore the givens of a shared vision of human society and assert diversity for its own sake without concern for unity.
Some Observations on Ecclesiological Method
Authors: Healy Nicholas 
Published: March 2013

Some commentators have called the twentieth century the century of the Church. Perhaps this is due in part to the unusual amount of theological activity devoted to ecclesiology. These efforts have produced major reforms in ecclesial structures and practices and important proposals for future reform. It is arguable, however, that although the theoretical discussion remains lively, in one sense it has come to a standstill. Theologians have constructed many a systematic treatise in ecclesiology, but they seem to be no further along than they were at the beginning of the century in establishing a set of basic principles, let alone in reaching a general consensus on the Church's nature and function. Even agreement on a common framework for discussion seems beyond our reach. Liberationists and feminists, neo-Augustinians and liberals, all seem to write largely for the like-minded. Their descriptions of the Church begin from scratch according to sets of principles often shared only by their own group; little attempt is made to enhance or discuss previous or conflicting ecclesiologies.
Peasant Wisdom, the “Our Father” and the Origins of Christianity
Authors: Kirk Alan Kenneth 
Published: March 2013

Text producers and text recipients are embedded in concrete social relations, . and text production, as communicative activity, is also social activity. As such, texts engage with a given set of social and cultural conditions, details of which, with varying degrees of clarity, are inscribed within the texts themselves. The "religious" texts which are the focus of Synoptic Gospels scholarship are no exception, for in ancient agrarian societies religious patterns of life were interwoven with social, political and economic relations[…]Therefore attention to the matrix of concrete social relations in which texts have their genesis can aid in interpretation of texts usually analyzed primarily from a theological perspective and/or assigned a restricted ecclesial Sitz im Leben. Conversely, careful location of a religious text within its generative socio-cultural context can aid theological interpretation while simultaneously protecting the latter from anachronism.
Revelation Theology and Theological Anthropology: Are they Incommensurable?
Authors: Lavin Margaret 
Published: March 2013

Revelation theology is generated by an intense endeavour to place the transcendent, triune and incarnate God at the centre of theological inquiry. It challenges any tendency to identify God with human experience through personal desires and thoughts, and any temptation to identify God with varieties of ideological expression. Theological anthropology, on the other hand, is generated by a transcendental phenomenology that is more concerned with the conditions of our human knowledge of revelation, through an analysis of the human experience of knowledge and freedom. In this approach, centrality of place is given to the historical nature of the human person as radically open toward the transcendent. Are these two means of theological inquiry incommensurable?
Rudolf Bultmann for the Twenty-First Century
Authors: Newlands George 
Published: March 2013

Rudolf Bultmann, perhaps the greatest New Testament scholar of the twentieth century, was born in Oldenburg in Germany in 1884. He studied in Marburg and was a professor in Marburg from 1921 to 1951. A member of the Confessing Church during the Nazi period, he lectured after the war in America (Yale) and in Britain (Gifford lectures, Edinburgh). For a period in the mid-twentieth century, Bultmann was the centre of discussion in New Testament studies. Systematic theology became for many writers largely a matter of New Testament hermeneutics, with the relation of faith to history as its focus. In philosophy, the tum to existentialism (around the work of Bultmann's friend and colleague Martin Heidegger) and issues in the philosophy of history were prominent. In writing his Ph.D. thesis on Faith and History in the work of Rudolf Bultmann, lain Nicol was researching at the heart of the contemporary problematic, in a school of theology-Glasgow-whose senior members were then at the cutting edge of Bultmann scholarship: John Macquarrie, Ian Henderson and Ronald Gregor Smith. I note with some embarrassment, however, that Zeit und Geschichte, the seminal Bultmann Festschrift of 1964, has been borrowed only three times in the thirty-seven years since publication-a sign of the times. Dr. Nicol took due note of the major criticisms which have been made of Bultmann. But he also found him a constructive dialogue partner for a contemporary theology.
Book Reviews
Authors: Forrest Robert , Dewart Joanne , Dourley John , Brown Schuyler , McKellar Hugh , Turner David , Wiebe Don , Kloppenborg John , Khan Abarahim 
Published: March 2013

Stefan Heym, The King David Report, reviewed by Robert W.E. Forrest C. T. McIntire and Ronald A. Wells, eds., History and Historical Understanding, reviewed by Joanne McWilliam Dewart John P. Dourley, The Psyche as Sacrament: A Comparative Study of C.G. Jung and Paul Tillich, reviewed by Schuyler Brown John P. Dourley, The Illness That We Are: A Jungian Critique of Christianity, reviewed by Schuyler Brown Antonio R. Gualtieri, Christianity and Native Traditions; Indigenization and syncretism among the Inuit and Dene of the Western Arctic, reviewed by Hugh D. McKellar Joan E. O'Donovan, George Grant and the Twilight of Justice, reviewed by David Turner John Kirby and William M. Thompson, ed., Voegelin and the Theologian: Ten Studies in Interpretation, reviewed by Don Wiebe Werner H. Kelber, The Oral and the Written Gospel. The Hermeneutics of Speaking and Writing in the Synoptic Tradition, Mark, Paul and Q, reviewed by John S. Kloppenborg Jeremy Walker, Kierkegaard: The Descent Into God, reviewed by Abrahim H. Khan
Acts of Impropriety: The Imbalance of History and Theology in Luke-Acts
Authors: Lüdemann Gerd 
Published: March 2013

Jews and Christians both have Scripture. Likewise, they both have a number of different traditions of interpretation for these texts. And, unfortunately, they also use and have used their Bibles as history books so as to establish the historical foundations of their respective faith communities. Even more upsetting is the fact that these biblical histories of faith communities continue to be taken more or less literally — even after the recent revolution in our understanding of historiography has enabled us to develop a new historical consciousness. We know that written histories contain both truth and falsehood, that history can be distorted or even falsified, and that such manipulations are capable of being discovered. Eyewitnesses most easily distinguish truth and falsehood, of course. As we go further back in time and the number of perspectives from which events are perceived increases, it becomes more difficult to distinguish between objective reporting and wilful or even unconscious "management" of the facts. In more than a few cases it may be impossible to know precisely what happened. Since no one can write entirely objective history, we must be ever alert to identify ideology when it plays a recognizable role. Since we are aware that history is manipulated even now in a world teeming with information, it seems to me entirely legitimate to begin with the assumption that in times when sources were few and less easily tested, history must have been even more commonly manipulated—and more thoroughly.
The Fate of Judas: Matthew 27:3-10
Authors: Conrad Audrey 
Published: March 2013

Of the synoptic gospels, only Matthew includes a passage (27:3-10) describing the fate of Judas Iscariot. The character of Judas and his actions are firmly in the tradition: some kind of betrayal took place which he personifies, and a locatable field is associated with him in living memory. Money is involved. To attribute greed to Judas as motive springs easily to mind as 'apologetic,' especially if the historical facts were not known to the tradition, or were known but were awkward to acknowledge. These traditional elements came to Matthew from his source, Mark. Matthew, along with Mark and Luke, accounts for Judas' acts as foreordained by scripture and foreknown by Jesus: the Messiah must be handed over, and Judas is the one who will do it. Mark and Luke leave it at that. Judas leaves the fellowship, and we are not told what becomes of him. Only Matthew elaborates on Judas' end. Why? What are his intentions? Where it stands, the pericope of Matthew 27:3-10 impedes the flow of an exciting story. It is implausible on a realistic level: surely there wasn't time between trials for the Sanhedrin to make a land purchase! Given Matthew's customary smoothness, the awkward narrative here suggests it was of major importance to him to include the content of 27:3-10. Although this pericope, and the gospel as a whole, permit much speculation regarding method of composition and historical veracity I will limit my investigation to Matthew's redactional agenda — the work of the author as author. To view Matthew as author more clearly, I will examine his use of Old Testament sources and themes in light of his methods and intentions as discernible elsewhere in the gospel, in the hope of discovering how the character of Judas Iscariot functioned for Matthew, and his motives for constructing the pericope as he did.
Where was the Gospel of Thomas Written?
Authors: Desjardins Michael 
Published: March 2013

Stevan Davies has helped to set the direction of modem scholarship in two areas throughout the 1980s. In The Revolt of the Widows: The Social World of the Apocryphal Acts, he argued that the New Testament apocryphal Acts originated in communities of continent Christian women striving for a new mode of self-expression. His study sparked others which explored the social and feminist ramifications of this type of early Christian literature.In a second innovative book, The Gospel of Thomas and Christian Wisdom, Davies sought to convince us, contrary to the current scholarly direction, that the Gospel of Thomas was not a gnostic document of concern mainly to historians of second-century Christianity. Instead, he encouraged us to set this gospel in the mid-first century, to understand it in the context of Christian baptismal initiation and instruction, and to view it as representative of contemporary Jewish wisdom speculations. The challenging nature of his thesis, the appended English translation of the Coptic text by David Cartlidge, and the absence of other accessible commentaries on this gospel all helped to make this book the most widely-read study on the Gos. Thom. in North America during the last decade. This paper emerges directly from The Gospel of Thomas and Christian Wisdom. It addresses more narrowly the issue of where the Gos. Thom. was written. Davies, setting this gospel in the mid-first century, hoped to dislodge the prevailing theory that it probably was written in Edessa.He proceeded in this task by rebutting three of Helmut Koester's arguments which favoured such an Edessene connection
Dreaming Together: Christians and Jews in the Twenty-first Century
Authors: Fisher Eugene 
Published: March 2013

On October 28, 1965, 221 Fathers of the Second Vatican Council voted placet ("it pleases") on one of the most controversial documents of the Council, the fourth section of the declaration of the Church's relationship with nonChristian religions, Nostra Aetate ("In Our Time"). Indeed, no statement of the Council better distilled, in the famous opening lines of Gaudium et Spes, "the joys and hopes, the griefs and anxieties" of the twentieth century, than these fifteen Latin sentences. The mid-1960s was a time of dreams and of the dashing of dreams. Set against the background of the Shoah, it was a time of prosperity and expanded vision in the United States and, I presume, in Canada as well, a time of the Peace Corps and civil rights, of Martin Luther King, Jack and Bobby Kennedy and of assassinations and Vietnam. Somehow, for many American Catholics and many American Jews, Nostra Aetate came to symbolize it all. After two millennia of often fractious and at times violent relations, the Roman Catholic Church, great in number and rich in tradition, made a turning, a heshon ha nefesh ("reconsideration of the soul") and turned its face for the first time in all those long, bitter centuries, toward rather than away from the Jewish people who had given it birth and early nurture. Today is not the time to reprise those centuries, with their ambiguities and in many ways remarkable spiritual fecundity in both Christianity and Judaism. Today, standing on the verge of the third millennium of the relationship, we look ahead. We allow ourselves to dream and in dreaming to search the horizon for landmarks on the way to a reconciliation between our two ancient traditions.
Experimental study of phase equilibria in the “SnO”–CaO–SiO2 system in equilibrium with tin metal
Authors: Xu Xiaoyong , Hayes Peter C. , Jak Evgueni 
Published: March 2013

Abstract
Experimental studies have been conducted to determine the primary phases and liquidus temperatures in the binary “SnO”–SiO2 and ternary “SnO”–CaO–SiO2 systems in equilibrium with tin metal between 1 148 and 1 673 K, using a high temperature equilibration and quenching technique followed by measurement of phase compositions using electron probe X-ray microanalysis. The melting temperature of cassiterite (SnO2) in equilibrium with tin metal was found to be between 1 398 and 1 403 K. The following primary phase fields were identified in the system: malayaite (CaSiSnO5), pseudo-wollastonite (CaSiO3), tridymite and cristobalite (SiO2), and cassiterite (SnO2). The liquidus of the “SnO”–CaO–SiO2 system is dominated by the tridymite or cristobalite (SiO2), and pseudo-wollastonite (CaSiO3) primary phase fields in the range of compositions studied.
Grain refining of aluminium alloys and silicon by means of boron-nitride particles
Authors: Wulf Eric , Alphei Lukas David , Westfal David , Seitz Jan-Marten , Schaper Mirko , Becker Jörg August , Feldhoff Armin , Bach Friedrich-Wilhelm 
Published: March 2013

Abstract
Investigations were carried out to grain refine the aluminium alloys Al-6Si (all compositions given in wt.%) and Al-12Si as well as pure silicon by means of inoculation using boron nitride nano-particles. Comparative tests were performed using both conventional grain refiners based on titanium as well as without inoculants. Analyses were performed using scanning electron microscopy, tensile testing, thermographic and metallographic techniques. In doing this, a significant effect on grain refining is verified by inoculating using boron nitride which exceeds the effect of conventional grain refiners.