bluuebunny/crossref_metadata_2025_split huggingface dataset:
Grid study on methane diffusion law in confined space of working face
Authors: Zhao Qian‐Kun , Qu Shi‐Jia , Wang Jian , Yang Huan 
Published: July 2024

AbstractThe layout of methane sensors in the working face cannot meet the needs for monitoring methane concentrations within confined spaces, and it is challenging to determine the precise locations for manual inspections. Therefore, the working face is firstly divided into different areas and grids. Then combined with the characteristics of methane emissions and the measured data on site, the boundary conditions of simulation experiments are set up and the research is carried out on the diffusion law of methane in the confined space of the working face under different conditions. The experimental results show that methane emission intensity from coal walls affects its distribution. As emission intensity rises, methane nearer the coal wall decreases, while methane further away increases. Among coal mining points, point 2 shows the widest methane diffusion range. Rising wind speeds decrease methane diffusion from the coal wall, increasing vertical diffusion distance. Methane from the coal wall shifts to the air inlet, while methane from the mining point diffuses increasingly to the downwind side. The location of the maximum methane concentration generated from falling coal and its transportation process is only related to the location of the coal mining point. The key areas for methane monitoring in confined spaces of the working face should be the overlapping locations of the vertical‐3 and vertical‐4 areas and the horizontal‐1 and horizontal‐3 areas. The key areas for manual inspection should be the overlapping locations of the vertical‐2 and vertical‐3 areas and the horizontal‐1 area.
The potential of repeated mean arterial pressure measurements for predicting early‐ and late‐onset pre‐eclampsia in twin pregnancies: Prediction model study
Authors: He Yunjiang , Xie Jinliang , Guo Yuna , Ma Jue , Wang Xiaojin , Lv Yao , Wu Siqi , Wei Siying , Xie Xianjing , Wang Bingshun 
Published: July 2024

AbstractObjectiveTo investigate the contribution of longitudinal mean arterial pressure (MAP) measurement during the first, second, and third trimesters of twin pregnancies to the prediction of pre‐eclampsia.MethodsA retrospective cohort study was conducted on women with twin pregnancies. Historical data between 2019 and 2021 were analyzed, including maternal characteristics and mean artery pressure measurements were obtained at 11–13, 22–24, and 28–33 weeks of gestation. The outcome measures included pre‐eclampsia with delivery <34 and ≥34 weeks of gestation. Models were developed using logistic regression, and predictive performance was evaluated using the area under the curve, detection rate at a given false‐positive rate of 10%, and calibration plots. Internal validation was conducted via bootstrapping.ResultsA total of 943 twin pregnancies, including 36 (3.82%) women who experienced early‐onset pre‐eclampsia and 93 (9.86%) who developed late‐onset pre‐eclampsia, were included in this study. To forecast pre‐eclampsia during the third trimester, the most accurate prediction for early‐onset pre‐eclampsia resulted from a combination of maternal factors and MAP measured during this trimester. The optimal predictive model for late‐onset pre‐eclampsia includes maternal factors and MAP data collected during the second and third trimesters. The areas under the curve were 0.937 (95% confidence interval [CI] 0.894–0.981) and 0.887 (95% CI 0.852–0.921), respectively. The corresponding detection rates were 83.33% (95% CI 66.53%–93.04%) for early‐onset pre‐eclampsia and 68.82% (95% CI 58.26%–77.80%) for late‐onset pre‐eclampsia.ConclusionRepeated measurements of MAP during pregnancy significantly improved the accuracy of late‐onset pre‐eclampsia prediction in twin pregnancies. The integration of longitudinal data into pre‐eclampsia screening may be an effective and valuable strategy.
Progressive colonic stenosis in an infant: Successful treatment with endoscopic balloon dilation
Authors: Plubjang Korppong , Chatpermporn Kanticha , Srisan Nimmita , Vejchapipat Paisarn , Phewplung Teerasak , Mahayosnond Atchara , Sintusek Palittiya 
Published: July 2024

AbstractAcquired colonic stenosis is extremely rare in infants and surgical resection is the mainstay of treatment. Endoscopic balloon dilation has shown success in treating bowel stenosis from inflammatory bowel disease but its application in infants with colonic strictures of other origin has not been widely explored. We report a 4‐week‐old male infant who developed significant abdominal distension due to progressive colonic stenosis, occurring 2 weeks following balloon valvuloplasty for his severe valvular pulmonary stenosis. The progressive colonic stenosis was successfully managed through endoscopic balloon dilation. Following this procedure, he exhibited clinical improvement, with subsequent imaging revealing no remaining stricture. Over the 16‐month follow‐up period, no clinical features suggestive of constipation or lower gut obstruction were observed. This case serves as evidence that endoscopic balloon dilation is a promising and safe therapeutic option for treating colonic stenosis in infants.
Predicted methane production from Italian ryegrass pastures with contrasting chemical composition under sheep grazing in Northern Norway
Authors: Lardy Q. , Ramin M. , Hetta M. , Jørgensen G. H. M. , Lind V. 
Published: July 2024

AbstractBackgroundThe Norwegian sheep farming system relies on forages, such as grass silage during winter and grazing cultivated leys and rangeland pastures during summer. Sheep and other ruminants produce enteric methane (CH4), a greenhouse gas of interest, and there is a need for reliable data on gas emissions from sheep capturing both the indoor feeding period and the grazing season. This study utilized an in vitro gas technique (with standard cow rumen fluid) and modeling approach to estimate CH4 production and fermentation patterns based on two different qualities of Italian ryegrass (Lolium multiflorum) pasture under sheep grazing.ResultsHerbage quality was examined for two 10‐day periods, in July and August. Differences in chemical composition of the herbage during these periods had an impact on herbage digestibility and CH4 production. Total gas production and CH4 levels were significantly higher for lower quality herbage grazed in July than for higher quality herbage grazed in August (p < 0.005). Production of volatile fatty acids in the rumen remained constant between the two periods, but the higher acetate to propionate (A/P) ratio correlated with the higher CH4 production.ConclusionThese findings suggest that pasture quality is an important factor to consider when implementing grazing strategies to reduce enteric CH4 production in sheep.
Unlocking the nutraceutical potential of Corylus avellana L. shells: microwave‐assisted extraction of phytochemicals with antiradical and anti‐diabetic properties
Authors: Maccarronello Anna E. , Cardullo Nunzio , Silva Ana Margarida , Di Francesco Antonella , Costa Paulo C. , Rodrigues Francisca , Muccilli Vera 
Published: July 2024

AbstractBACKGROUNDIn recent years, the demand for high‐quality natural extracts to be included in nutraceutical formulations has increased sharply. Hazelnut (Corylus avellana L.) shells (HZS) are underrated agricultural by‐products that could be exploited as a source of active ingredients with pro‐healthy properties. In the present study, a fully green microwave‐assisted extraction (MAE) method was established for the first time aiming to recover bioactive constituents from HZS with significant nutraceutical value. Key MAE parameters, including ethanol in water concentration, microwave power, irradiation time and solvent‐to‐powder ratio, were optimized through response surface methodology utilizing a Box–Behnken design to achieve the highest total phenolic content and antioxidant/antiradical activities in the final extract.RESULTSThe optimal MAE conditions (28% v/v ethanol/water, 270 s, 670 W, and 37 mL g−1) yielded an extract with significant scavenging capacity against reactive oxygen species and remarkable inhibitory activity towards both α‐amylase (IC50 = 7.73 μg mL−1) and α‐glucosidase (IC50 = 49.44 μg mL−1), demonstrating stronger hypoglycaemic properties than the anti‐diabetic drug acarbose. Additionally, fluorescence spectroscopy results highlighted the ability of the optimized extract from HZS (OHS‐E) to counteract advanced glycation end‐product formation throughout the glycation cascade in a dose‐dependent manner. Liquid chromatography/electrospray ionization‐tandem mass spectrometry profiling unveiled the presence of fatty acids and phenolic compounds, including lignans, flavonoids, gallic acid derivatives and diarylheptanoids. Lastly, the biocompatibility of OHS‐E was attested on HT29‐MTX and Caco‐2 intestinal cells.CONCLUSIONAltogether, these findings encourage the potential application of OHS‐E as an effective nutraceutical component against type 2 diabetes mellitus and oxidative stress. © 2024 The Author(s). Journal of the Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
Steps Toward Recapitulating Endothelium: A Perspective on the Next Generation of Hemocompatible Coatings
Authors: Witzdam Lena , White Tom , Rodriguez‐Emmenegger Cesar 
Published: July 2024

AbstractEndothelium, the lining in this blood vessel, orchestrates three main critical functions such as protecting blood components, modulating of hemostasis by secreting various inhibitors, and directing clot digestion (fibrinolysis) by activating tissue plasminogen activator. No other surface can perform these tasks; thus, the contact of blood and blood‐contacting medical devices inevitably leads to the activation of coagulation, often causing device failure, and thromboembolic complications. This perspective, first, discusses the biological mechanisms of activation of coagulation and highlights the efforts of advanced coatings to recapitulate one characteristic of endothelium, hereafter single functions of endothelium and noting necessity of the synergistic integration of its three main functions. Subsequently, it is emphasized that to overcome the challenges of blood compatibility an endothelium‐mimicking system is needed, proposing a synergy of bottom‐up synthetic biology, particularly synthetic cells, with passive‐ and bioactive surface coatings. Such integration holds promise for developing advanced biomaterials capable of recapitulating endothelial functions, thereby enhancing the hemocompatibility and performance of blood‐contacting medical devices.
On the spectrum of the algebra of bounded‐type symmetric analytic functions on ℓ1$\ell _1$
Authors: Chernega Iryna , Galindo Pablo , Zagorodnyuk Andriy 
Published: July 2024

AbstractWe obtain a complete description of the spectrum of the Fréchet algebra of symmetric analytic functions bounded on balls on the sequence space . This is achieved after proving that on the analogous algebra for , , the radius function of any evaluation homomorphism , coincides with the norm of .
Boundedness in a quasilinear forager–exploiter model
Authors: Wang Jianping , Zhang Qianying 
Published: July 2024

AbstractWe study a forager–exploiter model with nonlinear diffusions:
where is a smooth bounded domain, is a nonnegative bounded function, satisfying
with some sufficiently large . Global‐in‐time solutions are established for corresponding Neumann initial‐boundary value problem.
The energy decay rate of a transmission system governed by the degenerate wave equation with drift and under heat conduction with the memory effect
Authors: Akil Mohammad , Fragnelli Genni , Issa Ibtissam 
Published: July 2024

AbstractIn this paper, we investigate the stabilization of the transmission problem of the degenerate wave equation and the heat equation under the Coleman–Gurtin heat conduction law or Gurtin–Pipkin law with the memory effect. We investigate the polynomial stability of this system when employing the Coleman–Gurtin heat conduction, establishing a decay rate of type . Next, we demonstrate exponential stability in the case when Gurtin–Pipkin heat conduction is applied.
Highly Efficient Recycling Waste Plastic into Hydrogen and Carbon Nanotubes through a Double Layer Microwave‐Assisted Pyrolysis Method
Authors: Wang Song , Hu Yanbing , Lu Shuai , Zhang Bin , Li Sanxi , Chen Xuecheng 
Published: July 2024

AbstractMicrowave‐assisted pyrolysis of PE to hydrogen and carbon material has great potential to solve the problem of waste PE induced white pollution and provide a promising way to produce hydrogen energy. To increase the hydrogen yield, a new microwave‐assisted pyrolysis procedure should be developed. In the present study, a facile double‐layer microwave‐assisted pyrolysis (DLMP) method is developed to pyrolyze PE. Within this method, PE can be converted to hydrogen, multiwalled carbon nanotubes with extremely high efficiency compared with the traditional methods. A high hydrogen yield of 66.4 mmol g−1PE is achieved, which is ≈93% of the upper limit of the theoretical hydrogen yield generated from the PE pyrolysis process. The mechanism of high hydrogen yield during the microwave‐assisted pyrolysis of PE using the DLMP method is also clarified in detail. The DLMP method paved the potential way for recycling plastic waste into high‐value‐added products.
Corporate strategies to protect software innovation: Empirical evidences from South Korea
Authors: Choi Jeong Woo , Kim Kyunam , Kim Yeonbae 
Published: July 2024

AbstractThe purpose of this study is to determine whether there are blind spots in decision making to protect innovation by examining how formal and informal protection systems affect software innovation. We empirically compared the innovation activities of 218 software companies with 261 information and communication technology (ICT) manufacturing companies in South Korea. Our results confirm that formal protection system alone is insufficient to protect software innovation, but its effect may vary depending on the corporate size. While, combination of patent with complicated designs is effective. More sophisticated policy to complement informal protections for small and medium‐sized enterprises with less than 100 employees is needed.
AAPM task group report 288: Recommendations for guiding radiotherapy event narratives
Authors: Thomadsen Bruce , Kapur Ajay , Blankenship Bette , Caldwell Barrett , Claps Lindsey , Cunningham Joanne , Elee Jennifer , Evans Suzanne , Ford Eric , Gilley Debbie , Hayden Sandra , Hintenlang Kathleen , Kapoor Rishabh , Kildea John , Kroger Linda , Kujundzic Ksenija , Liang Qing , Mutic Sasa , O'Donovan Anita , O'Hara Michael , Ouhib Zoubir , Palta Jatinder , Pawlicki Todd , Salter William , Schmidt Stacey , Tripathi Sugata 
Published: July 2024

AbstractIncident reporting and learning systems provide an opportunity to identify systemic vulnerabilities that contribute to incidents and potentially degrade quality. The narrative of an incident is intended to provide a clear, easy to understand description of an incident. Unclear, incomplete or poorly organized narratives compromise the ability to learn from them. This report provides guidance for drafting effective narratives, with particular attention to the use of narratives in incident reporting and learning systems (IRLS). Examples are given that compare effective and less than effective narratives. This report is mostly directed to organizations that maintain IRLS, but also may be helpful for individuals who desire to write a useful narrative for entry into such a system. Recommendations include the following: (1) Systems should allow a one‐ or two‐sentence, free‐text synopsis of an incident without guessing at causes; (2) Information included should form a sequence of events with chronology; and (3) Reporting and learning systems should consider using the headings suggested to guide the reporter through the narrative: (a) incident occurrences and actions by role; (b) prior circumstances and actions; (c) method by which the incident was identified; (d) equipment related details if relevant; (e) recovery actions by role; (f) relevant time span between responses; (g) and how individuals affected during or immediately after incident. When possible and appropriate, supplementary information including relevant data elements should be included using numerical scales or drop‐down choices outside of the narrative. Information that should not be included in the narrative includes: (a) patient health information (PHI); (b) conjecture or blame; (c) jargon abbreviations or details without specifying their significance; (d) causal analysis.
Comprehensive analysis including in‐game spending and violent game playing in patients with internet gaming disorder
Authors: Minami Haruka , Shirai Toshiyuki , Okada Shohei , Miyachi Masao , Tanifuji Takaki , Okazaki Satoshi , Horai Tadasu , Mouri Kentaro , Otsuka Ikuo , Hishimoto Akitoyo 
Published: July 2024

AbstractAimInternet gaming disorder (IGD) is receiving increasing attention. In particular, violent gameplay or in‐game spending affects the psychiatric conditions and economic difficulties of patients. We conducted regression analysis and path analysis to investigate the associations between a comprehensive list of factors in patients with IGD, including the degree of internet or gaming dependence, developmental problems, family background, severity of depression, sleeping habits, in‐game spending, and first‐person shooter (FPS) and third‐person shooter (TPS) game playing.MethodsThe participants were 47 Japanese individuals (39 males and 8 females) aged ≤20 years diagnosed with IGD with complete data from the internet addiction test, autism spectrum quotient, Quick Inventory of Depressive Symptomatology, and Pittsburgh Sleep Quality Index. All participants were asked whether their parents have divorce history, whether they have siblings, whether they play FPS or TPS games, and whether they engage in in‐game spending. Firstly, we compared these factors between males and females; secondly, we conducted regression analysis and path analysis in male patients.ResultsAs for simple comparison between sex, female patients showed greater severity of IGD and depressive score. In regression analysis of male patients, significant associations were found between FPS or TPS game playing and in‐game spending. We also created path diagrams.ConclusionThe results of the comprehensive analyses suggest the possibility that bidirectional synergistic effects could be achieved by gradually reducing both violent game playing and in‐game spending. The concept of internet dependence has a wide range of meanings, and for each subtype, it is important to consider the background that led to the dependence to make individualized environmental adjustments and provide psychotherapy.
Superhydrophobic surface development via atmospheric pressure plasma deposition of cyclic silazane
Authors: Rendon Piedrahita Camilo , Baba Kamal , Quintana Robert , Choquet Patrick 
Published: July 2024

Abstract1,2,3,4,5,6,7,8‐Octamethylcyclotetrasilazane (OTMSD), a cyclic silazane precursor, is deposited via atmospheric pressure plasma onto a substrate. The resulting coating exhibits a dual surface roughness, contributing to a significant reduction of surface wettability. Notably, the coating exhibits superhydrophobic characteristics, proven by a water contact angle of approximately 170°, hysteresis angle below 10°, very low tilting angle (<10°), and droplet‐bouncing effect. Importantly, this superhydrophobicity is achieved using OTMSD as fluorine‐free precursor with low reactivity to water. Furthermore, the deposition process is carried out using a commercially available plasma device highlighting its practicality and scalability for large‐scale production.
TPCA‐1 compound, inhibiting testis‐specific serine/threonine protein kinase 3 for potential male sterile in Bombyx mori
Authors: Liu Lianlian , Lu Xiuping , Fan Zeling , Deng Jing , Zhang Surui , Zhang Lulu , Zha Xingfu 
Published: July 2024

AbstractBACKGROUNDProtein kinases are a type of transferase enzyme that catalyze the phosphorylation of protein substrates, including receptor proteins. Testis‐specific serine/threonine kinases (TSSKs) are a highly conserved group of protein kinases found in various organisms. They play an essential role in male reproduction by influencing sperm development and function.RESULTSIn this study, we report on the characterization of BmTSSK3, a TSSK from the silkworm, Bombyx mori. We found that BmTSSK3 is specifically expressed in the testis and localized to the sperm flagella, particularly in the sperm tail cyst. Furthermore, we developed BmTSSK3 inhibitors through molecular docking and binding assays. Small molecules 5‐(4‐Fluorophenyl)‐2‐ureidothiophene‐3‐carboxamide (TPCA‐1) and Imidurea were identified to bind to BmTSSK3. Using site‐specific mutation technology, we identified amino acid residues R134 and S184 as crucial binding sites for small molecules. RNA interference assay and Western blot analysis showed that knockdown of BmTSSK3 significantly decreased histone 3 phosphorylation. To confirm the inhibitory effect of these small molecules, we treated silkworm testes with TPCA‐1 and observed a strong inhibitory effect.CONCLUSIONTPCA‐1 is an inhibitor of BmTSSK3, which raises its potential as a future candidate for male sterility of the silkworm. Thus, this study may offer a novel strategy for sterile silkworms as well as insects. © 2024 Society of Chemical Industry.
Efficient Study Design and Analysis of Longitudinal Dose–Response Data Using Fractional Polynomials
Authors: Hartley Benjamin F. , Lunn Dave , Mander Adrian P. 
Published: July 2024

ABSTRACTCorrectly characterising the dose–response relationship and taking the correct dose forward for further study is a critical part of the drug development process. We use optimal design theory to compare different designs and show that using longitudinal data from all available timepoints in a continuous‐time dose–response model can substantially increase the efficiency of estimation of the dose–response compared to a single timepoint model. We give theoretical results to calculate the efficiency gains for a large class of these models. For example, a linearly growing Emax dose–response in a population with a between/within‐patient variance ratio ranging from 0.1 to 1 measured at six visits can be estimated with between 1.43 and 2.22 times relative efficiency gain, or equivalently, with 30% to a 55% reduced sample size, compared to a single model of the final timepoint. Fractional polynomials are a flexible way to incorporate data from repeated measurements, increasing precision without imposing strong constraints. Longitudinal dose–response models using two fractional polynomial terms are robust to mis‐specification of the true longitudinal process while maintaining, often large, efficiency gains. These models have applications for characterising the dose–response at interim or final analyses.