bluuebunny/crossref_metadata_2025_split huggingface dataset:
The development and validation of an internet-based training package for the management of perineal trauma following childbirth: MaternityPEARLS
Authors: Mahmud Ayesha , Kettle Christine , Bick Debra , Rowley Claire , Rathod Trishna , Belcher John , Abdelmaguid Mohamed M , Ismail Khaled M K 
Published: March 2013

Abstract

Background
Birth-related perineal trauma has a major impact on women's health. Appropriate management of perineal injuries requires clinical knowledge and skill. At present, there is no agreement as to what constitutes an effective clinical training programme, despite the presence of sufficient evidence to support standardised perineal repair techniques. To address this deficiency, we developed and validated an interactive distance learning multi-professional training package called MaternityPEARLS.

Method
MaternityPEARLS was developed as a comprehensive e-learning package in 2010. The main aim of the MaternityPEARLS project was to develop, refine and validate this multi-professional e-learning tool. The effect of MaternityPEARLS in improving clinical skills and knowledge was compared with two other training models; traditional training (lectures + model-based hands on training) and offline computer lab-based training. Midwives and obstetricians were recruited for each training modality from three maternity units. An analysis of covariance was done to assess the effects of clinical profession and years of experience on scoring within each group. Feedback on MaternityPEARLS was also collected from participants. The project started in January 2010 and was completed in December 2010.

Results
Thirty-eight participants were included in the study. Pretraining and post-training scores in each group showed considerable improvement in skill scores (p&lt;0.001 in all groups). Mean changes were similar across all three groups for knowledge (3.24 (SD 5.38), 3.00 (SD 3.74), 3.30 (SD 3.73)) and skill (25.34 (SD 8.96), 22.82 (SD 9.24), 20.7 (SD 9.76)) in the traditional, offline computer lab-based and e-learning groups, respectively. There was no evidence of any effect of clinical experience and baseline knowledge on outcomes.

Conclusions
MaternityPEARLS is the first validated perineal trauma management e-learning package. It provides a level of improvement in skill and knowledge comparable to traditional methods of training. However, as an e-learning system, it has the advantage of ensuring the delivery of a standardised, continuously updated curriculum that has global accessibility.
Puerperal development of ewes following dystocia: a retrospective analysis of two approaches to caesarean section
Authors: Ennen S. , Scholz M. , Voigt K. , Failing K. , Wehrend A. 
Published: March 2013

The objective of this study was to retrospectively analyse the puerperal development of ewes referred to a veterinary teaching hospital following caesarean section in comparison with assisted parturition. Laparotomy was performed either via left flank incision (group 1, n=86) or ventral mid‐line approach (group 2, n=33). Both groups were compared with ewes following non‐surgical intervention (group 3, n=73). The overall fetal death rate was 41 per cent. There was no significant difference in fetal deaths between groups 1 and 2, but assisted delivery led to a higher number of liveborn lambs compared with caesarean section (P<0.05). Seven ewes (3.6 per cent) died or were euthanased on welfare grounds during caesarean surgery, and the overall maternal mortality rate following dystocia in the postpartum period was 10.9 per cent. While there was no significant difference between groups 1 and 2 in the percentage of ewes developing healing disorders, the complications that occurred were more severe after the left flank approach (P=0.04), and the mean hospitalisation period was significantly longer in group 1 than in group 2 (P<0.05), leading to the conclusion that ventral mid‐line laparotomy has some advantages over a left flank approach.
Object tracking in the presence of occlusions using multiple cameras
Authors: Ercan Ali O. , Gamal Abbas El , Guibas Leonidas J. 
Published: April 2013

This article describes a sensor network approach to tracking a single object in the presence of static and moving occluders using a network of cameras. To conserve communication bandwidth and energy, we combine a task-driven approach with camera subset selection. In the task-driven approach, each camera first performs simple local processing to detect the horizontal position of the object in the image. This information is then sent to a cluster head to track the object. We assume the locations of the static occluders to be known, but only prior statistics on the positions of the moving occluders are available. A noisy perspective camera measurement model is introduced, where occlusions are captured through occlusion indicator functions. An auxiliary particle filter that incorporates the occluder information is used to track the object. The camera subset selection algorithm uses the minimum mean square error of the best linear estimate of the object position as a metric, and tracking is performed using only the selected subset of cameras.
Using simulations and preselected subsets of cameras, we investigate (i) the dependency of the tracker performance on the accuracy of the moving occluder priors, (ii) the trade-off between the number of cameras and the occluder prior accuracy required to achieve a prescribed tracker performance, and (iii) the importance of having occluder priors to the tracker performance as the number of occluders increases. We find that computing moving occluder priors may not be worthwhile, unless it can be obtained cheaply and to high accuracy. We also investigate the effect of dynamically selecting the subset of camera nodes used in tracking on the tracking performance. We show through simulations that a greedy selection algorithm performs close to the brute-force method and outperforms other heuristics, and the performance achieved by greedily selecting a small fraction of the cameras is close to that of using all the cameras.
On mobile sensor assisted field coverage
Authors: Wang Dan , Liu Jiangchuan , Zhang Qian 
Published: April 2013

Providing field coverage is a key task in many sensor network applications. With unevenly distributed static sensors, quality coverage with acceptable network lifetime is often difficult to achieve. Fortunately, recent advances on embedded and robotic systems make mobile sensors possible, and we suggest that a small set of mobile sensors can be leveraged toward a cost-effective solution for field coverage. There are, however, a series of fundamental questions to be answered in such a hybrid network of static and mobile sensors: (1) Given the expected coverage quality and system lifetime, how many mobile sensors should be deployed? (2) What are the necessary coverage contributions from each type of sensors? (3) What working and moving patterns should the sensors adopt to achieve the desired coverage contributions?
In this article, we offer an analytical study on these problems, and the results lead to a practical system design. Specifically, we present an optimal algorithm for calculating the contributions from different types of sensors, which fully exploits the potentials of the mobile sensors and maximizes the network lifetime. We then present a random walk model for the mobile sensors. The model is distributed with very low control overhead. Its parameters can be fine-tuned to match the moving capability of different mobile sensors and the demands from a broad spectrum of applications. A node collaboration scheme is then introduced to further enhance the system performance.
We demonstrate through analysis and simulation that, in our mobile assisted design, a small set of mobile sensors can effectively address the uneven distribution of the static sensors and significantly improve the coverage quality.
Trends and Impacts of Real and Financial Globalization in the People's Republic of China and India since the 1980s
Authors: Srinivasan TN 
Published: April 2013

The dynamic process of integration of national economies has a long history, with two distinct waves: one, from the middle of the 19th century until its interruption with outbreak of the First World War in 1913 till the end of the Second World War in 1945. The second wave is ongoing dating from 1950. Two sub-processes of integration are usually distinguished. The first, called real integration related to flows of goods, services and factors across borders; the second called financial integration related to financial flows of claims on the nominal returns on financial assets. Financial integration has had a checkered history. Private financial flows, particularly debt flows, were evident in the first wave. During the second wave, debt flows, both intergovernmental and private banking lending were dominant during 1950–1980. Only after 1980, private non-debt flows particularly equity flows accelerated.This paper's primary focus is on the real and financial integration and their impact on trade, growth and poverty in the world's two dominant developing countries in emerging markets, namely the People's Republic of China (PRC) and India. The paper also discusses the reforms of institutional (domestic and multinational) foundations of real and financial integration, particularly the World Trade Organization, the World Bank, the International Monetary Fund, and the Group of 20. The impacts of the 2008–2009 financial crisis on the PRC and India are noted and the need for domestic financial sector reforms in both for them to cope with and respond to future financial crises is pointed out. Attention is drawn to the inadequacy of available analytical tools, in particular the absence of an appropriately integrated model of real and financial sectors to enable a meaningful assessment of the impact of financial shocks on the real sector.
Characterization of El-Tih kaolin quality using mineralogical, geochemical and geostatistical analyses
Authors: Masoud A. A. , Christidis G. , Koike K. 
Published: March 2013

AbstractDetailed multi-scale characterization of the kaolin quality and the controlling depositional environment is crucial for optimal quality upgrading and for prioritizing potential exploitation areas. In the present work, the quality of El-Tih kaolin, Egypt, was investigated using the chemical/mineralogical characteristics as well as the field observations of the clay. Chemical analysis of major oxides was carried out using energy dispersive X-ray fluorescence (EDS-XRF) spectrometry. Mineralogical analyses were carried out using X-ray diffraction (XRD) and scanning electron microscopy coupled with wavelength-dispersive X-ray spectroscopy (SEM-WDS). Spatial heterogeneity of the quality was evaluated applying kriging geostatistical techniques and potential zones were identified.Results clarified an upward gradual deterioration of the quality via a decrease in the Al2O3content and thickness of the clay layers, and an increase in the TiO2content. According to the kriging maps, areas of high potentiality indices (PI) characterized by high Al2O3and low SiO2content and maximum thickness of the kaolin are located to the west and east, and decrease toward the central part of the study area. The high PI zones are dominated by pseudo-hexagonal platy kaolinite, often forming accordion- and book-like aggregates with subordinate quartz and traces of Fe and Ti oxides, yielding minimal TiO2and Fe2O3contents. These zones of high PI are considered optimal for exploitation. Kaolinite was formed as a result of intensive weathering of rhyolite/granite and basalt in the source area, and subsequent erosion, transportation and deposition of the weathering mantles in a flood environment with marked depositional energy variations. Results allowed comparison with worldwide kaolin occurrences, and suggested the suitability of the studied kaolins for use in paper coating and filling and in higher-grade ceramics, after removal of free Fe- and Ti-oxide impurities.
Structural interpretation of anion exchange in divalent copper hydroxysalt minerals
Authors: Stanimirova TS. , Dencheva S. , Kirov G. 
Published: March 2013

AbstractMinerals with the general formula Cu4(OH)6A2/nn ± pH2O (A = Cl–, NO3–, SO42–) were synthesized and their behaviour following treatment with chloride, nitrate and sulfate solutions was studied by powder XRD and SEM. Two types of transformation were found: (1) an ion-exchange reaction manifested by preservation of both the precursor's morphology and structural type; (2) a dissolution-crystallization mechanism characterized by changes in the structural type and the morphology.The results were considered by simultaneous application of the binary presentation of the structures, a bond valence approach and the ion-exchange ability. It was found that the structures of minerals with ion-exchange properties are built from similar layered structural unit of edge-shared and corner-shared Jahn-Teller square frameworks and different interstitial complexes of exchangeable ions, water molecules and cation-water groups. On the basis of their structural features the position of the investigated minerals in mineralogical classifications is also discussed.
Alteration of clay minerals in a sedimentary caprock and its use in geothermal prospecting: an example from Mt. Amiata
Authors: Battaglia S. , Gherardi F. , Gianelli G. , Leoni L. , Lezzerini M. 
Published: March 2013

AbstractThis research work deals with chlorite-vermiculite mixed-layer stability under hydrothermal and metamorphic conditions. We used as a case study a clayey flysch unit cropping out in an active geothermal area near to a Recent volcano (Mt. Amiata) in central Italy. The geothermal gradient is higher than the world average and temperatures over 100°C can occur at less than 1 km depth. The mineralogical data, obtained from X-Ray Power Diffraction (XRPD) analysis of clay samples from the same geologic unit, show that the primary anchimetamorphic mineral assemblage (illite, chlorite, illite-smectite mixed layers) is accompanied by secondary phases, such as chlorite-vermiculite mixed-layers and calcite. Reactive flow modelling was used to outline a realistic water-rock (W/R) interaction process able to generate the new minerals. In the numerical simulation, the pristine shale was made to react with a local thermal spring, at an estimated but realistic carbonate reservoir temperature. The simulation predicts that, at a temperature of 120°C, clinochlore dissolves and vermiculite crystallizes, a good proxy of the chlorite-vermiculite crystallization process. Under low water/rock conditions the proportions of the clay minerals (illite, chlorite, smectite and vermiculite) are comparable with the analytical results. The simulation also shows that temperatures higher than 120°C enhance the vermiculite formation. We conclude that the chlorite-vermiculite mixed-layers formed in the recent past due to the upflow of thermal water which permeated the flysch unit. This result indicates that the alteration of the clayey cap-rocks of geothermal reservoirs is enhanced by the interaction with geothermal fluids, and can be used as a prospecting tool.
Insights into cationic methyl violet 6B dye–kaolinite interactions: kinetic, equilibrium and thermodynamic studies
Authors: Sargin İ. , Ünlü N. 
Published: March 2013

AbstractIn this study, adsorption and adsorption kinetics of methyl violet dye from aqueous solutions onto kaolinite were investigated. The effects of adsorbent dosage, pH, ionic strength, contact time, temperature and initial dye concentration were studied. Kinetic and thermodynamic parameters were determined using experimental data. Adsorption capacity decreased with increasing ionic strength. Changes in the initial pH of the dye solution in a range close to the dye's natural pH (i.e. ∼ pH 5.0) values affected adsorption capacity slightly, indicating that adsorption studies could be carried out at the dye's natural pH. The adsorption process followed the Freundlich-type adsorption isotherms and pseudo-second order type adsorption kinetics. However, an intraparticle diffusion process was found to have effects in adsorption processes. Thermodynamic parameters were calculated from the experimental data and enthalpy of the adsorption, ΔH0, was found to be –6.82 kJ mol–1, indicating physisorption nature of the adsorption. Other thermodynamic parameters, ΔS0 and DG0, were also calculated. Negative values of ΔG0 indicated that the adsorption process for methyl violet on kaolinite is spontaneous.
Iron-bearing smectites: a revised relationship between structural Fe, b cell edge lengths and refractive indices
Authors: Heuser M. , Andrieux P. , Petit S. , Stanjek H. 
Published: March 2013

AbstractStructural iron in smectites correlates with the cell edge length b and increases the refractive index. The cell edge length b is usually obtained from the position of the (060) reflection, but in this work we show that such b values differ from the values obtained from Rietveld fits because contributions from (hkl) reflections shift the position of the (060) reflection. The correlation between Fe and cell edge length b was significant (r2 > 0.99); the relationship is b [Å] = 8.9977(0.0035) + 0.1117(0.0032) × Fetot. Furthermore, we present for the first time measurements of the refractive index n of Fe-bearing smectites, applying a recently published turbidity method (Weidler & Friedrich, 2007). The refractive index correlates both with structural iron (r2 = 0.64) and with b (r2 = 0.94).
Synthesis, characterization and electrorheological properties of biodegradable chitosan/bentonite composites
Authors: Cabuk M. , Yavuz M. , Unal H. I. , Erol O. 
Published: March 2013

AbstractBiodegradable chitosan/bentonite composites with three different compositions were synthesized by the intercalation method using cetyltrimethylammonium bromide as the cationic surfactant. The composites were characterized using conductivity, density, particle size measurements, FTIR, TGA, XRD and SEM methods. Colloidal stabilities of the suspensions prepared in silicone oil (SO) were observed to increase with decreasing density. The effects of dispersed particle concentration, shear rate, electric field strength, electric field frequency and temperature on the electrorheological (ER) activities of the suspensions were investigated. The electric field viscosities of the suspensions showed typical shear thinning non-Newtonian viscoelastic behaviour. Yield stresses of the suspensions were observed to change in proportion to the square of applied electric field (E). Further, according to creep and creep-recovery analysis, reversible viscoelastic deformations were observed in the suspensions under E ≠ 0 kV mm–1.
Evidence for the requirement of 14-3-3eta (YWHAH) in meiotic spindle assembly during mouse oocyte maturation
Authors: De Santanu , Kline Douglas 
Published: April 2013

Abstract
Background
The 14-3-3 (YWHA) proteins are central mediators in various cellular signaling pathways regulating development and growth, including cell cycle regulation. We previously reported that all seven mammalian 14-3-3 isoforms are expressed in mouse oocytes and eggs and that, 14-3-3η (YWHAH) accumulates and co-localizes in the region of meiotic spindle in mouse eggs matured in vivo. Therefore, we investigated the role of 14-3-3η in spindle formation during mouse oocyte maturation.

Results
Examination of oocytes matured in vitro demonstrated that 14-3-3η accumulates in both meiosis I and II spindles. To explore if 14-3-3η interacts directly with α-tubulin in meiotic spindles, we performed an in situ proximity ligation assay that can detect intracellular protein-protein interactions at the single molecule level and which allows visualization of the actual interaction sites. This assay revealed a marked interaction between 14-3-3η and α-tubulin at the metaphase II spindle. To demonstrate a functional role for 14-3-3η in oocyte maturation, mouse oocytes were microinjected with a translation-blocking morpholino oligonucleotide against 14-3-3η mRNA to reduce 14-3-3η protein synthesis during oocyte maturation. Meiotic spindles in those cells were examined by immunofluorescence staining of 14-3-3η and α-tubulin along with observation of DNA. In 76% of cells injected with the morpholino, meiotic spindles were found to be deformed or absent and there was reduced or no accumulation of 14-3-3η in the spindle region. Those cells contained clumped chromosomes, with no polar body formation. Immunofluorescence staining of 14-3-3η and α-tubulin in control eggs matured in vitro from uninjected oocytes and oocytes microinjected with the ineffective, inverted form of a morpholino against 14-3-3η, a morpholino against 14-3-3γ, or deionized water showed normal, bipolar spindles.

Conclusions
The results indicate that 14-3-3η is essential for normal meiotic spindle formation during in vitro maturation of mouse oocytes, in part by interacting with α-tubulin, to regulate the assembly of microtubules. These data add to our understanding of the roles of 14-3-3 proteins in mouse oocyte maturation and mammalian reproduction.
Pathophysiology and treatment of focal segmental glomerulosclerosis: the role of animal models
Authors: de Mik Sylvana ML , Hoogduijn Martin J , de Bruin Ron W , Dor Frank JMF 
Published: April 2013

Abstract
Focal segmental glomerulosclerosis (FSGS) is a kidney disease with progressive glomerular scarring and a clinical presentation of nephrotic syndrome. FSGS is a common primary glomerular disorder that causes renal dysfunction which progresses slowly over time to end-stage renal disease. Most cases of FSGS are idiopathic Although kidney transplantation is a potentially curative treatment, 40% of patients have recurrence of FSGS after transplantation. In this review a brief summary of the pathogenesis causing FSGS in humans is given, and a variety of animal models used to study FSGS is discussed. These animal models include the reduction of renal mass by resecting 5/6 of the kidney, reduction of renal mass due to systemic diseases such as hypertension, hyperlipidemia or SLE, drug-induced FSGS using adriamycin, puromycin or streptozotocin, virus-induced FSGS, genetically-induced FSGS such as via Mpv-17 inactivation and α-actinin 4 and podocin knockouts, and a model for circulating permeability factors. In addition, an animal model that spontaneously develops FSGS is discussed. To date, there is no exact understanding of the pathogenesis of idiopathic FSGS, and there is no definite curative treatment. One requirement facilitating FSGS research is an animal model that resembles human FSGS. Most animal models induce secondary forms of FSGS in an acute manner. The ideal animal model for primary FSGS, however, should mimic the human primary form in that it develops spontaneously and has a slow chronic progression. Such models are currently not available. We conclude that there is a need for a better animal model to investigate the pathogenesis and potential treatment options of FSGS.