bluuebunny/crossref_metadata_2025_split huggingface dataset:
Successful Vaginal delivery of locked twin in a tertiary care centre of Western region of Nepal
Authors: Pandey MR , Ghimire P , Ghimire P 
Published: May 2014

Here we report a case of unbooked primigravida who was admitted to the labor room with labor pain. Ultrasonography revealed twin pregnancy with first twin presenting as breech. After coming head of the first breech fetus locked with the head of the second cephalic fetus during labor. Successful Vaginal delivery of both the live fetuses was performed along with mediolateral episiotomy following disengagement of head. Nepal Journal of Medical Sciences | Volume 03 | Number 01 | January-June 2014 | Page 74-75 DOI: http://dx.doi.org/10.3126/njms.v3i1.10366
Isolated bilateral fetal pleural effusion: diagnosed on antenatal ultrasonography
Authors: Ansari S , Ahmad K , Dhungel K , Gupta MK , Rauniyar RK , Kumar A 
Published: May 2014

Isolated fetal pleural effusion is a rare condition with high mortality. When there are no other findings of hydropsfetalis or documented etiology such as inflammatory, iatrogenic or cardiac problems exist, isolated pleural effusion is considered. We present a rare case of isolated bilateral fetal pleural effusion diagnosed prenatally on ultrasonography. Nepal Journal of Medical Sciences | Volume 03 | Number 01 | January-June 2014 | Page 76-78 DOI: http://dx.doi.org/10.3126/njms.v3i1.10367
A portal of educational resources: providing evidence for matching pedagogy with technology
Authors: Di Blas Nicoletta , Fiore Alessandro , Mainetti Luca , Vergallo Roberto , Paolini Paolo 
Published: May 2014

The TPACK (Technology, Pedagogy and Content Knowledge) model presents the three types of knowledge that are necessary to implement a successful technology-based educational activity. It highlights how the intersections between TPK (Technological Pedagogical Knowledge), PCK (Pedagogical Content Knowledge) and TCK (Technological Content Knowledge) are not a sheer sum up of their components but new types of knowledge. This paper focuses on TPK, the intersection between technology knowledge and pedagogy knowledge – a crucial field of investigation. Actually, technology in education is not just an add-on but is literally reshaping teaching/learning paradigms. Technology modifies pedagogy and pedagogy dictates requirements to technology. In order to pursue this research, an empirical approach was taken, building a repository (back-end) and a portal (front-end) of about 300 real-life educational experiences run at school. Educational portals are not new, but they generally emphasise content. Instead, in our portal, technology and pedagogy take centre stage. Experiences are classified according to more than 30 categories (‘facets’) and more than 200 facet values, all revolving around the pedagogical implementation and the technology used. The portal (an innovative piece of technology) supports sophisticated ‘exploratory’ sessions of use, targeted at researchers (investigating the TPK intersection), teachers (looking for inspiration in their daily jobs) and decision makers (making decisions about the introduction of technology into schools).Keywords: educational portal; educational repository; open educational resources; educational technology; the TPACK model(Published: 06 May 2014)Citation: Research in Learning Technology 2014, 22: 22906 - http://dx.doi.org/10.3402/rlt.v22.22906
Le grand retour des États ?
Authors: Novak Stéphanie 
Published: May 2014

La crise de la zone euro a attiré l’attention publique sur le rôle croissant du Conseil européen. Peut-on pour autant soutenir que la gouvernance européenne est à présent principalement mue par une dynamique intergouvernementale ? Cet article tente de répondre à cette question en analysant les extensions récentes de la méthode communautaire et le rôle croissant du Conseil européen dans la coordination des politiques.
La gouvernance économique durant et après la crise : vers la disparition de la Commission européenne ?
Authors: Bauer Michael W. , Becker Stefan , Richet Isabelle 
Published: May 2014

Alors que la récente crise économique et financière a refaçonné l’ordre institutionnel de la gouvernance économique de l’Union européenne, le rôle de la Commission est remis en question. Cette dernière est, en général, présentée sur le déclin, mais les auteurs avancent ici une perspective plus nuancée. Sa capacité à déterminer les priorités de l’Union s’est en effet affaiblie à cause du leadership croissant du Conseil européen ; pourtant, la mise en œuvre d’une grande majorité de décisions concernant la gouvernance économique dépend toujours de l’exécutif de l’Union. Le rôle de la Commission, armée de compétences plus conséquentes en matière d’exécution, est peut-être moins visible, mais certainement pas moins important.
La BCE dans la crise : Qui décide quoi ?
Authors: Fontan Clément 
Published: May 2014

Quelle a été la portée des décisions prises par la Banque centrale européenne pendant la crise de la zone euro ? Afin de répondre à cette question, il faut envisager la bce , non pas sous l’angle de ses seules compétences officielles, mais comme un acteur politique qui cherche à exercer une influence au-delà du strict domaine monétaire. Son impact porte alors sur les systèmes socio-économiques nationaux, les règles de gouvernance européenne et le système de supervision financière.
Réglementations européennes et politiques sociales nationales : le grand écart
Authors: Hayward Jack , Richet Isabelle 
Published: May 2014

Avant la commission Delors, l’Union européenne réglementait de façon minimale la politique sociale car les gouvernements des États membres considéraient leurs États-providence comme des éléments essentiels de la cohésion nationale. Les États membres ont ensuite agi de façons diverses pour éviter de mettre en œuvre les réglementations européennes et ont également utilisé leur influence au sein du Conseil pour les bloquer ou les modifier en amont. La Cour de justice de l’Union est parvenue à instaurer une certaine uniformité des règlements de la politique sociale. Entre les « partenaires sociaux », un recours accru à la marchéisation, à la déréglementation et à l’autorégulation a favorisé les employeurs et les contribuables au détriment des salariés et des citoyens en général. L’austérité financière imposée a entraîné une précarisation variable des services de santé et de retraite dans les différents pays.
Rove beetles (Coleoptera: Staphylinidae) in Ontario, Canada soybean agroecosystems: assemblage diversity, composition, seasonality, and habitat use
Authors: Brunke A.J. , Bahlai C.A. , Klimaszewski J. , Hallett R.H. 
Published: May 2014

AbstractRove beetles (Coleoptera: Staphylinidae) are recognised as important components of agroecosystems and are best known for their contribution to biological control as predators of arthropod pests. Unfortunately, knowledge of their bionomics in North American agroecosystems is sparse. Therefore, soybean-hedgerow agroecosystems in Ontario, Canada, were surveyed in 2009–2010 to identify common, widespread members of the assemblage and characterise their seasonal activity patterns. The potential for refuge habitat in adjacent hedgerows was assessed outside of the growing season. The rove beetle assemblage of soybeans during the growing season was found to be a less diverse subset of that found in surrounding hedgerow areas, especially with respect to native species. Both native and non-native species were common (>1% activity density). Based on literature records, most common species were predaceous, univoltine, and adult overwintering. Most common species exhibited the highest activity density midway through the growing season and all were detected in hedgerow habitats outside the growing season. Comparisons with the staphylinid fauna of other North American agroecosystems revealed several common species to dominate assemblages under a wide variety of conditions. This research provides a framework for future agroecological studies of this poorly understood, but abundant and diverse, assemblage of beetles.
Simian Virus 40 Large T Antigen Induces IFN-Stimulated Genes through ATR Kinase
Authors: Forero Adriana , Giacobbi Nicholas S. , McCormick Kevin D. , Gjoerup Ole V. , Bakkenist Christopher J. , Pipas James M. , Sarkar Saumendra N. 
Published: May 2014

Abstract
Polyomaviruses encode a large T Ag (LT), a multifunctional protein essential for the regulation of both viral and host cell gene expression and productive viral infection. Previously, we have shown that stable expression of LT protein results in upregulation of genes involved in the IFN induction and signaling pathway. In this study, we focus on the cellular signaling mechanism that leads to the induction of IFN responses by LT. Our results show that ectopic expression of SV40 LT results in the induction of IFN-stimulated genes (ISGs) in human fibroblasts and confers an antiviral state. We describe a LT-initiated DNA damage response (DDR) that activates IFN regulatory factor 1, causing IFN-β production and consequent ISG expression in human cells. This IFN-β and ISG induction is dependent on ataxia-telangiectasia mutated and Rad3-related (ATR) kinase, but independent of ATM. ATR kinase inhibition using a selective kinase inhibitor (ETP-46464) caused a decrease in IFN regulatory factor 1 stabilization and ISG expression. Furthermore, expression of a mutant LT that does not induce DDR also does not induce IFN-β and ISGs. These results show that, in the absence of viral infection, LT-initiated activation of ATR-dependent DDR is sufficient for the induction of an IFN-β–mediated innate immune response in human cells. Thus, we have uncovered a novel and critical role for ATR as a mediator of antiviral responses utilizing LT.
DISTRIBUCIÓN DE Heliopsis longipes (Heliantheae: Asteraceae), UN RECURSO ENDÉMICO DEL CENTRO DE MÉXICO
Authors: Cilia-López V. Gabriela , Aguirre-Rivera J. Rogelio , Espinosa-Reyes Guillermo , Flores-Cano Jorge A. , Reyes-Agüero J. Antonio , Juárez-Flores Bertha I. 
Published: May 2014

Heliopsis longipes is a perennial herb endemic to Sierra de Álvarez and Sierra Gorda in central México. It is a species of major economic importance within its genus, due to the traditional uses of its root. Chemical and pharmacological studies have been performed with H. longipes roots, however recent studies regarding its distribution are lacking. The objective of the current study was to establish and document the geographic distribution and existing ecologic conditions of H. longipes. A review of published works regarding this species, as well as an examination of herbarium specimens has been conducted. Explorations in Sierra de Álvarez and Sierra Gorda were also conducted to locate populations of H. longipes. In each site, the physical and biological factors associated with the population were recorded. Heliopsis. longipes is distributed in the states of San Luis Potosí, Guanajuato and Querétaro, in steep canyons with oak and oak-pine forests and substrates of igneous origin, in Sierra de Álvarez and Sierra Gorda.
Examination of heat treatments at preservation of grape must
Authors: Korzenszky Péter , Molnár Erik 
Published: May 2014

Heat treatment is a well-known process in food preservation. It is made to avoid and to slow down food deterioration. The process was developed by Louise Pasteur French scientist to avoid late among others wine further fermentation. The different heat treatments influence the shelf life in food production. In our article we present the process of grape must fermentation, as grape must is the base material of wine production. The treatment of harvested fresh grape juice has a big influence on end product quality. It is our experiments we examined the same grape must with four different methods in closed and in open spaces to determine CO2 concentration change. There are four different methods for treatment of grape juice: boiling, microwave treatment, treatment by water bath thermostat and a control without treatment. As a result of the comparison it can be stated that the heat treatment delays the start of fermentation, thereby increasing shelf life of grape must. However, no significant differences were found between two fermentation of heat-treated grape must by the microwave and water-bath thermostat. The different heat treatment of grape must base materials was done at the laboratory in Faculty of Mechanical Engineering of Szent István University. The origin of the table grapes used for the examination was Gödöllő-hillside.
Amino acids and fatty acids profile of chia (Salvia hispanica L.) and flax (Linum usitatissimum L.) seed
Authors: Nitrayová Soňa , Brestenský Matej , Heger Jaroslav , Patráš Peter , Rafay Ján , Sirotkin Alexander 
Published: May 2014

The seeds of most plants are rich in various nutrients and can provide a lot of useful health benefits. The objective of this study was to determine and compare differences in fat, fatty acids, crude protein and amino acids concentrations for chia and flax seeds. Study was carried out using brown and gold seeds of Flax (Linum usitatissimum L.) and Chia (Salvia hispanica L.). The mean protein content in tested seeds ranged from 211.8 to 252.5 g/kg dry matter and in chia seed was about 13.10% higher than the average value of crude protein content in brown and gold flax seed (223.25 g/kg dry matter). Differences in the content of individual amino acids among the seeds were not statistically significant (P <0.05), except that for glutamic acid. Percentage of the essential to the total amino acids, which is considered as indicator of protein quality, was 37.87%, 33.76% and 35.18%, for chia, brown and gold flax seed respectively, which demonstrates the high quality of these proteins. The average fat content of flax seeds was about 71.42 g/kg higher than that in chia seed (321.37 g/kg dry matter). The fatty acids composition showed the presence of palmitic, stearic, oleic, linoleic, α- linolenic and arachidic fatty acids in all tested samples. The α-linolenic acid constitutes on average 54.38% of the total fatty acids of flax seeds and 63.79% of chia seed, and for linoleic acid it was 15.30% and 18.89%. All seeds had low n-6 PUFA / n-3 PUFA ratio. Results of our study confirmed the excellent quality of protein and fat in chia seed, brown and gold flax seed samples. There was no significant effect of the flax seed coat colour for all measured values. Chia seed is the richest of n-3 PUFA α-linolenic fatty acid in the vegetable world. Both, flax seed and chia seed are the good choice of healthy food to maintain a balanced serum lipid profile. It must be pointed that flax seeds must be ground to release their nutrients, but chia seeds do not.
Monitoring of color and pH in muscles of pork leg (m. adductor and m. semimembranosus)
Authors: Bednářová Martina , Kamení­k Josef , Sláková Alena , Pavlí­k Zdeněk , Tremlová Bohuslava 
Published: May 2014

In order to identify PSE pork meat, pH and color testing was performed directly in a cutting plant (72 hours post mortem) in this research. Specifically pork leg muscles musculi adductor (AD) and semimembranosus (SM) from five selected suppliers (A, B, C, D, E) were examined. Twenty samples of meat for each muscle were examined from each supplier. The measured pH values ranged from 5.43 to 5.63, and the L* values from 46.13 to 57.18. No statistically significant differences in pH values and color were detected among the various suppliers with the exception of the a* and b* parameters for two suppliers, namely A and B (p<0.01). On the contrary, a statistically significant difference (p<0.5) was recorded between individual muscles (AD/SM) across all the suppliers (A, B, C, D, E) with the exception of a* parameter from suppliers B, C, D, E, and pH values for the E supplier. Our results revealed that individual muscles differ in values of pH and color. In comparison with literature, pH and lightness L* values in musculus adductor point to PSE (pale, soft and exudative) meat, while the values of musculus semimebranosus to RFN (red, firm and non-exudative). Use of PSE meat in production of meat products can cause several problems. In particular, it causes light color, low water-holding capacity, poor fat emulsifying ability, lower yield, granular or crumbly texture and poor consistency of the finished product. Therefore classification of the meat directly cutting plant may be possible solution for this problem. The finished product pruduces from muscles of musculi semimembranosus can obtain better quality than the finished product from musculi adductor.
Characterisation of Lactobacilli from eweÊ¼s and goatÊ¼s milk for their further processing re-utilisation
Authors: Kološta Miroslav , Slottová Anna , Drončovský Maroš , Klapáčová Lýdia , Kmeť Vladimí­r , Bujňáková Dobroslava , Lauková Andrea , Greif Gabriel , Greifová Maria , Tomáška Martin 
Published: May 2014

Raw ewe's and goat's milk is a good source for isolation of wild lactobacilli which are able to bring unique processing properties in development of dairy products - cheeses or fermented dairy products. 34 strains of lactobacilli were isolated, purified and identified from fermented ewe's and goat's dairy products. These products were processed without thermal treatment and without using of any commercial starters. After preliminary selection, the final collection of 5 strains was established. The strains were identified as: Lbc. plantarum (2), Lbc. paraplantarum (1), Lbc. paracasei (1) and Lbc. johnsonii (1). Except two strains, all were able to coagulate milk. After hydrolysis of lactose in milk, two strains were able to form sensorial attractive coagulate too. All of the strains were homofermentative, they produced lactic acid but they did not produce CO2. Their ability to produce diacetyl was low. They did not show strong proteolytic activity. All strains grew at 30 °C and 37 °C, however Lbc. johnsonii much slower at 30 °C than the others. Except Lbc. johnsonii, all strains tolerated 2% concentration of NaCl and even in presence of 5% concentration of NaCl their growth was inhibited only moderately. All of characterized strains can be provisionally used as starter or starter adjuncts in dairy technology, during production of cheeses or fermented milk products from pasteurised milk. These results will be used in further processing studies of isolated strains and will be supplemented with other properties e.g. safety, probiotic and antimicrobial properties.
Functional Outcome After Anal Sphincter Injury and Treatment With Mesenchymal Stem Cells
Authors: Salcedo Levilester , Penn Marc , Damaser Margot , Balog Brian , Zutshi Massarat 
Published: May 2014

Abstract

This research demonstrates the regenerative effects of mesenchymal stem cells (MSCs) on the injured anal sphincter by comparing anal sphincter pressures following intramuscular and serial intravascular MSC infusion in a rat model of anal sphincter injury. Fifty rats were divided into injury (n = 35) and no injury (NI; n = 15) groups. Each group was further divided into i.m., serial i.v., or no-treatment (n = 5) groups and followed for 5 weeks. The injury consisted of an excision of 25% of the anal sphincter complex. Twenty-four hours after injury, 5 × 105 green fluorescent protein-labeled MSCs in 0.2 ml of phosphate-buffered saline (PBS) or PBS alone (sham) were injected into the anal sphincter for i.m. treatment; i.v. and sham i.v. treatments were delivered daily for 6 consecutive days via the tail vein. Anal pressures were recorded before injury and 10 days and 5 weeks after treatment. Ten days after i.m. MSC treatment, resting and peak pressures were significantly increased compared with those in sham i.m. treatment (p &lt; .001). When compared with the NI group, the injury groups had anal pressures that were not significantly different 5 weeks after i.m./i.v. treatment. Both resting and peak pressures were also significantly increased after i.m./i.v. MSC treatment compared with treatment with PBS (p &lt; .001), suggesting recovery. Statistical analysis was done using paired t test with Bonferroni correction. Marked decrease in fibrosis and scar tissue was seen in both MSC-treated groups. Both i.m. and i.v. MSC treatment after injury caused an increase in anal pressures sustained at 5 weeks, although fewer cells were injected i.m. The MSC-treated groups showed less scarring than the PBS-treated groups, with the i.v. infusion group showing the least scarring.
Amniotic Fluid-Derived Mesenchymal Stem Cells Prevent Fibrosis and Preserve Renal Function in a Preclinical Porcine Model of Kidney Transplantation
Authors: Baulier Edouard , Favreau Frederic , Le Corf Amélie , Jayle Christophe , Schneider Fabrice , Goujon Jean-Michel , Feraud Olivier , Bennaceur-Griscelli Annelise , Hauet Thierry , Turhan Ali G. 
Published: May 2014

AbstractIt is well known that ischemia/reperfusion injuries strongly affect the success of human organ transplantation. Development of interstitial fibrosis and tubular atrophy is the main deleterious phenomenon involved. Stem cells are a promising therapeutic tool already validated in various ischemic diseases. Amniotic fluid-derived mesenchymal stem cells (af-MSCs), a subpopulation of multipotent cells identified in amniotic fluid, are known to secrete growth factors and anti-inflammatory cytokines. In addition, these cells are easy to collect, present higher proliferation and self-renewal rates compared with other adult stem cells (ASCs), and are suitable for banking. Consequently, af-MSCs represent a promising source of stem cells for regenerative therapies in humans. To determine the efficiency and the safety of af-MSC infusion in a preclinical porcine model of renal autotransplantation, we injected autologous af-MSCs in the renal artery 6 days after transplantation. The af-MSC injection improved glomerular and tubular functions, leading to full renal function recovery and abrogated fibrosis development at 3 months. The strong proof of concept generated by this translational porcine model is a first step toward evaluation of af-MSC-based therapies in human kidney transplantation.
Treinamento resistido para crianças e adolescentes
Authors: Benedet Jucemar , Freddi Juliana Carla , Luciano Alexandre Paiva , Almeida Fernando De Souza , Silva Gilvan Lira da , Hinnig Patrícia De Fragas , Adami Fernando 
Published: May 2014

Em uma sociedade onde a aparência corporal é muito valorizada, as academias de musculação são procuradas de forma cada vez mais precoce pelos jovens. O objetivo deste estudo foi fazer uma análise retrospectiva sobre a evolução das recomendações do treinamento resistido para crianças e adolescentes. A busca bibliográfica foi realizada nas bases de dados PubMed, Web of Science e Scielo. As estratégias de busca incluíram a combinação dos seguintes descritores: “resistance training”, “strength training”, “weight-training” “adolescents”, “children” e “youth”. A busca bibliográfica resultou em 349 artigos. A leitura e análise dos resumos pelos autores resultou na seleção de 25 artigos, respeitando os critérios de inclusão adotados. Os resultados indicam que as primeiras publicações sobre o tema ocorreram em 1990 e, a partir de então, observou-se uma evolução substancial tanto no número de publicações quanto nas abordagens do treinamento resistido para crianças e adolescentes. A análise dos artigos mostra que atualmente é possível encontrar informações qualificadas cujos indicativos suportam a prática do treinamento resistido por parte de crianças e adolescentes de forma segura e eficaz. Pode-se concluir que não restam dúvidas sobre os benefícios do treinamento resistido para a saúde dos jovens, respeitadas as recomendações vigentes as quais são pontuadas ao longo desta revisão. Convém destacar que permanecem latentes questões associadas às respostas crônicas do treinamento resistido nesta faixa etária, assim como dúvidas em relação à prescrição para as diferentes idades, ergonomia dos equipamentos e ambientes.