bluuebunny/crossref_metadata_2025_split huggingface dataset:
Occupation and head and neck cancer in women—Results of the ICARE study
Authors: Carton Matthieu , Guida Florence , Paget‐Bailly Sophie , Cyr Diane , Radoi Loredana , Sanchez Marie , Schmaus Annie , Cénée Sylvie , Papadopoulos Alexandra , Menvielle Gwenn , Févotte Joëlle , Pilorget Corinne , Molinié Florence , Bara Simona , Stücke Isabelle , Luce Danièle 
Published: October 2014

BackgroundFew occupational studies have addressed head and neck cancer, and these studies have been predominantly conducted in men. Accordingly, our objective was to investigate the association between head and neck cancer and occupation in women.MethodsICARE, a French population‐based case–control study, included 296 squamous cell carcinomas of the head and neck in women and 775 controls. Lifelong occupational history was collected. Odds ratios (ORs) and 95% confidence intervals (CI), adjusted for smoking, alcohol drinking and education level, were estimated for occupations and industries.ResultsAn elevated OR was observed for working proprietors working for 10 years or more (OR = 3.83, 95% CI: 1.12–13.0) with a significant trend with duration of employment (P = 0.047). Elevated but non‐significant ORs were observed for street vendors (OR = 3.76, 95% CI: 0.99–14.3, P for trend = 0.13), bakers (OR = 4.19, 95% CI: 0.63–27.9, P for trend = 0.06), and welders and flame cutters (OR = 2.18, 95% CI: 0.33–14.4, P for trend = 0.05).ConclusionsThis exploratory study suggests a role of occupational exposures in the development of HN cancer in women. Further investigations of exposures to specific agents are needed. Am. J. Ind. Med. 57:1386–1397, 2014. © 2014 Wiley Periodicals, Inc.
Grades of undernutrition and socioeconomic status influence cognitive development in school children of Kolkata
Authors: Ghosh Satabdi , Chowdhury Sutanu Dutta , Chandra Ananga Mohan , Ghosh Tusharkanti 
Published: October 2014

ABSTRACTCognitive development of children is influenced by different environmental factors like nutritional and socio‐economic status. The objectives of the present study were to determine the influence of grades of undernutrition and socio‐economic status (SES) on the cognitive development of school children of Kolkata. Five hundred sixty six (566) school children having 5–12 years of age were selected from different schools of Kolkata. The cognitive development was measured by the scores of Raven's colored progressive matrices (RCPM). The chronic and acute nutritional statuses were measured from height‐for‐age (HAZ) and weight‐for‐age (WAZ) Z scores respectively with reference to the values of WHO. SES was determined by updated Kuppuswamy scale. The prevalences of undernutrition in the observed children were 57.95% (according to HAZ) and 52.82% (according to WAZ). The age dependent growth curve of RCPM scores of the observed children remains in between the 10th and 25th centile of British children. The children belonging to superior and intellectual deficit IQ classes were 21.55 and 36.40%, respectively of the total subjects. Most of the subjects belong to lower middle (39.93%) and upper middle (36.40%) class of SES. RCPM scores of school children were gradually decreased with the grades of undernutrition and SES. RCPM scores were significantly correlated with HAZ, WAZ, SES, age, and sex (P < 0.001) and strongly associated with HAZ, SES, age, and sex (P < 0.001, P < 0.05). Present study indicates that cognitive development of school children of Kolkata is influenced by the grade of undernutrition and SES. Am J Phys Anthropol 156:274–285, 2015. © 2014 Wiley Periodicals, Inc.
Human–wildlife conflict: Proximate predictors of aggression between humans and rhesus macaques in India
Authors: Beisner Brianne A. , Heagerty Allison , Seil Shannon K. , Balasubramaniam Krishna N. , Atwill Edward R. , Gupta Brij K. , Tyagi Praveen C. , Chauhan Netrapal P.S. , Bonal B.S. , Sinha P.R. , McCowan Brenda 
Published: October 2014

ABSTRACTMacaques live in close contact with humans across South and Southeast Asia, and direct interaction is frequent. Aggressive contact is a concern in many locations, particularly among populations of rhesus and longtail macaques that co‐inhabit urbanized cities and towns with humans. We investigated the proximate factors influencing the occurrence of macaque aggression toward humans as well as human aggression toward macaques to determine the extent to which human behavior elicits macaque aggression and vice versa. We conducted a 3‐month study of four free‐ranging populations of rhesus macaques in Dehradun, India from October–December 2012, using event sampling to record all instances of human‐macaque interaction (N = 3120). Our results show that while human aggression was predicted by the potential for economic losses or damage, macaque aggression was influenced by aggressive or intimidating behavior by humans as well as recent rates of conspecific aggression. Further, adult female macaques participated in aggression more frequently than expected, whereas adult and subadult males participated as frequently as expected. Our analyses demonstrate that neither human nor macaque aggression is unprovoked. Rather, both humans and macaques are responding to one another's behavior. Mitigation of human‐primate conflict, and indeed other types of human‐wildlife conflict in such coupled systems, will require a holistic investigation of the ways in which each participant is responding to, and consequently altering, the behavior of the other. Am J Phys Anthropol 156:286–294, 2015. © 2014 Wiley Periodicals, Inc.
Controlled dual release study of curcumin and a 4‐aminoquinoline analog from gum acacia containing hydrogels
Authors: Aderibigbe Blessing , Sadiku Emmanuel , Jayaramudu Jarugala , Sinha Ray Suprakas 
Published: October 2014

ABSTRACTThe potential of gum acacia containing hydrogels as controlled dual‐drug delivery systems for antiprotozoal agents was investigated. 4‐Aminoquinoline analog and curcumin were selected as model drugs because they exhibit antiprotozoal activity. The maximum release time was greater for curcumin than for the 4‐aminoquinoline analog at 37°C, thereby enabling the active ingredients to work over different periods of time. 4‐Aminoquinoline analog exhibited a short term release profile while curcumin exhibited a sustained and long term release profile. The release profiles of the drugs were found to be influenced by the degree of crosslinking of the hydrogel network with gum acacia. The release profiles were analyzed using a power law equation proposed by Peppas. The release mechanism of the 4‐aminoquinoline was found to be anomalous transport while that of curcumin was quasi‐Fickian diffusion mechanism in all the hydrogel networks according to the release exponent. The preliminary results suggest that these systems are potential dual‐drug delivery system for antiprotozoal agents with different pharmacokinetics. © 2014 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2015, 132, 41613.
Hierarchical Hybrid Symbolic Robot Motion Planning and Control
Authors: Karimoddini Ali , Lin Hai 
Published: October 2014

AbstractThis paper addresses the motion planning problem using hybrid symbolic techniques. The proposed approach develops a unified hierarchical hybrid control framework using a bismulation‐based abstraction technique over the partitioned motion space that can be applied to autonomous aerial robots (3‐D symbolic motion planning) or ground vehicles (2‐D symbolic motion planning). The bisimulation relation between the abstracted model and the original continuous system guarantees that their behaviors are the same. This allows to design a discrete supervisor for the abstracted model, and then, the designed supervisor can be applied to the original system while the closed‐loop behavior does not change. To apply the discrete supervisor to the original continuous system, an interface layer is developed, which on the one hand translates discrete commands of the supervisor to a continuous form applicable to the continuous plant and on the other hand, abstracts the continuous signals of the continuous low layer to discrete symbols understandable by the supervisor. The proposed algorithm is verified through implementation of a hybrid symbolic algorithm for the formation control of unmanned aerial vehicles.
Morphology‐Tuned Exceptional Catalytic Activity of Porous‐Polymer‐Supported Mn3O4 in Aerobic sp3 CH Bond Oxidation of Aromatic Hydrocarbons and Alcohols
Authors: Mondal John , Borah Parijat , Sreejith Sivaramapanicker , Nguyen Kim Truc , Han Xiguang , Ma Xing , Zhao Yanli 
Published: October 2014

AbstractMn3O4 nanomaterials with different morphologies (sphere, nanowire, and octahedron) embedded into functionalized nanoporous polymers were developed by a facile one‐pot solvothermal technique at different temperatures. These Mn3O4‐based hybrid materials could behave as heterogeneous nanocatalysts to perform sp3 CH bond oxidation of aromatic hydrocarbons and alcohols with molecular oxygen as an economic oxidant. Catalytic activity could be effectively tuned by changing the morphology of incorporated Mn3O4 in nanoporous polymer. These Mn3O4‐based hybrid materials exhibited remarkable catalytic performance for sp3 CH bond oxidation as compared with bare Mn3O4 nanoparticles. Mn3O4 with octahedral morphology in nanoporous polymer exhibited the highest catalytic activity on account of its more exposed crystallographic planes and edges. These Mn3O4‐based nanocatalysts could be recycled and reused for consecutive catalytic cycles without a significant loss of catalytic activity.
Nanostructured Metallic Electrocatalysts for Carbon Dioxide Reduction
Authors: Lu Qi , Rosen Jonathan , Jiao Feng 
Published: October 2014

AbstractThe recent development of nanostructured electrocatalysts for CO2 reduction has attracted much attention because they exhibit unique properties compared to their bulk counterparts. In this minireview, the latest studies on electrocatalytic CO2 reduction with a focus on the advances of nanostructured metallic electrocatalysts are reviewed and discussed. The distinct catalytic properties and potential challenges of nanostructured electrocatalysts are summarized. The behavior of nanosized catalysts in ionic liquid electrolytes is also discussed. Ideas for the design of next‐generation electrocatalysts by taking the advantages of nanostructured materials are proposed.
Characterisation of Taxlllaids A–G; Natural Products from Xenorhabdus indica
Authors: Kronenwerth Max , Bozhüyük Kenan A. J. , Kahnt Astrid S. , Steinhilber Dieter , Gaudriault Sophie , Kaiser Marcel , Bode Helge B. 
Published: October 2014

AbstractSix new lipodepsipeptides and an additional linear derivative named taxlllaids A–G (1–7) have been identified in the entomopathogenic bacterium Xenorhabdus indica. The structures of the main compounds have been solved by detailed NMR spectroscopic analysis and the structures of minor derivatives were elucidated by a combination of labelling experiments and detailed MS experiments. The absolute configuration of the taxlllaids was deduced by using the advanced Marfey method and analysis of the biosynthesis gene cluster showing the presence of epimerisation domains, which was subsequently proved to be correct by solid‐phase peptide synthesis of all taxlllaids. The exchange of a single amino acid in the adenylation domain was shown to be responsible for substrate promiscuity of the third A domain, resulting in the incorporation of leucine, phenylalanine or tyrosine. Bioactivity testing revealed the taxlllaids to be weakly active against Plasmodium falciparum and against a number of eukaryotic cell lines.
A Highly Stereoselective and Flexible Strategy for the Convergent Synthesis of Long‐Chain Polydeoxypropionates: Application towards the Synthesis of the Glycolipid Membrane Components Hydroxyphthioceranic and Phthioceranic Acid
Authors: Pischl Matthias C. , Weise Christian F. , Haseloff Stefan , Müller Marc‐André , Pfaltz Andreas , Schneider Christoph 
Published: October 2014

AbstractA highly stereocontrolled and flexible access to biologically relevant polydeoxypropionates in optically pure form has been developed. Taking advantage of our previously established strategy for the asymmetric and stereodivergent synthesis of trideoxypropionate building blocks, we have now been able to assemble large polydeoxypropionate chains with defined configuration in a highly convergent manner. Central steps of this approach include two Suzuki–Miyaura cross‐coupling reactions with subsequent highly diastereoselective hydrogenations to join three advanced synthetic intermediates in excellent yield and with full stereochemical control. We have applied this strategy successfully towards the asymmetric synthesis of glycolipid membrane components phthioceranic acid and hydroxyphthioceranic acid, the latter of which was synthesized on a half‐gram scale.
Highly Enantioselective Ring‐Opening Reactions of Aziridines with Indole and Its Application in the Building of C3‐Halogenated Pyrroloindolines
Authors: Yang Dongxu , Wang Linqing , Han Fengxia , Li Dan , Zhao Depeng , Cao Yiming , Ma Yunxia , Kong Weidong , Sun Quantao , Wang Rui 
Published: October 2014

AbstractA magnesium‐catalyzed asymmetric ring‐opening reaction of aziridine with indole has been realized by employing commercially available chiral ligands. Both of the enantiomers of the ring‐opening product could be obtained with good yields and a high level of enantioselectivity. The corresponding ring‐opening product could be further transformed to various types of enantioenriched C3‐halogenated‐pyrroloindolines.
Stereocontrolled Synthesis of Benzo[k]fluoranthenes—An Unexpected Isomerization Mediated by Rhodacyclopentadiene
Authors: Xu Shengjie , Chen Kejuan , Chen Hui , Yao Jiannian , Zhu Xiaozhang 
Published: October 2014

AbstractHerein, a RhIII‐catalyzed stereocontrolled synthesis of benzo[k]fluoranthenes is reported. It was found that the unexpected E/Z isomerization was highly sensitive to the electronic effects of the substituents on the aryl groups. Theoretical calculations revealed that this controllable stereochemistry originates from the mediation of rhodacyclopentadiene intermediates during the isomerization. The fact that similar stereochemistry was observed when using an IrIII catalyst further suggests a certain generality of this discovery toward some other transition metals.
Competition and Cooperation in Dynamic Replication Networks
Authors: Dadon Zehavit , Wagner Nathaniel , Alasibi Samaa , Samiappan Manickasundaram , Mukherjee Rakesh , Ashkenasy Gonen 
Published: October 2014

AbstractThe simultaneous replication of six coiled‐coil peptide mutants by reversible thiol–thioester exchange reactions is described. Experimental analysis of the time dependent evolution of networks formed by the peptides under different conditions reveals a complex web of molecular interactions and consequent mutant replication, governed by competition for resources and by autocatalytic and/or cross‐catalytic template‐assisted reactions. A kinetic model, first of its kind, is then introduced, allowing simulation of varied network behaviour as a consequence of changing competition and cooperation scenarios. We suggest that by clarifying the kinetic description of these relatively complex dynamic networks, both at early stages of the reaction far from equilibrium and at later stages approaching equilibrium, one lays the foundation for studying dynamic networks out‐of‐equilibrium in the near future.
Cell‐specific and developmental expression of lectican‐cleaving proteases in mouse hippocampus and neocortex
Authors: Levy C. , Brooks J.M. , Chen J. , Su J. , Fox M.A. 
Published: October 2014

ABSTRACTMounting evidence has demonstrated that a specialized extracellular matrix exists in the mammalian brain and that this glycoprotein‐rich matrix contributes to many aspects of brain development and function. The most prominent supramolecular assemblies of these extracellular matrix glycoproteins are perineuronal nets, specialized lattice‐like structures that surround the cell bodies and proximal neurites of select classes of interneurons. Perineuronal nets are composed of lecticans, a family of chondroitin sulfate proteoglycans that includes aggrecan, brevican, neurocan, and versican. These lattice‐like structures emerge late in postnatal brain development, coinciding with the ending of critical periods of brain development. Despite our knowledge of the presence of lecticans in perineuronal nets and their importance in regulating synaptic plasticity, we know little about the development or distribution of the extracellular proteases that are responsible for their cleavage and turnover. A subset of a large family of extracellular proteases (called a disintegrin and metalloproteinase with thrombospondin motifs [ADAMTS]) is responsible for endogenously cleaving lecticans. We therefore explored the expression pattern of two aggrecan‐degrading ADAMTS family members, ADAMTS15 and ADAMTS4, in the hippocampus and neocortex. Here, we show that both lectican‐degrading metalloproteases are present in these brain regions and that each exhibits a distinct temporal and spatial expression pattern.Adamts15mRNA is expressed exclusively by parvalbumin‐expressing interneurons during synaptogenesis, whereasAdamts4mRNA is exclusively generated by telencephalic oligodendrocytes during myelination. Thus, ADAMTS15 and ADAMTS4 not only exhibit unique cellular expression patterns but their developmental upregulation by these cell types coincides with critical aspects of neural development. J. Comp. Neurol. 523:629–648, 2015. © 2014 Wiley Periodicals, Inc.
Transcriptome profiling of developing photoreceptor subtypes reveals candidate genes involved in avian photoreceptor diversification
Authors: Enright Jennifer M. , Lawrence Karen A. , Hadzic Tarik , Corbo Joseph C. 
Published: October 2014

ABSTRACTAvian photoreceptors are a diverse class of neurons, comprised of four single cones, the two members of the double cone, and rods. The signaling events and transcriptional regulators driving the differentiation of these diverse photoreceptors are largely unknown. In addition, many distinctive features of photoreceptor subtypes, including spectral tuning, oil droplet size and pigmentation, synaptic targets, and spatial patterning, have been well characterized, but the molecular mechanisms underlying these attributes have not been explored. To identify genes specifically expressed in distinct chicken (Gallus gallus) photoreceptor subtypes, we developed fluorescent reporters that label photoreceptor subpopulations, isolated these subpopulations by using fluorescence‐activated cell sorting, and subjected them to next‐generation sequencing. By comparing the expression profiles of photoreceptors labeled with rhodopsin, red opsin, green opsin, and violet opsin reporters, we have identified hundreds of differentially expressed genes that may underlie the distinctive features of these photoreceptor subtypes. These genes are involved in a variety of processes, including phototransduction, transcriptional regulation, cell adhesion, maintenance of intra‐ and extracellular structure, and metabolism. Of particular note are a variety of differentially expressed transcription factors, which may drive and maintain photoreceptor diversity, and cell adhesion molecules, which may mediate spatial patterning of photoreceptors and act to establish retinal circuitry. These analyses provide a framework for future studies that will dissect the role of these various factors in the differentiation of avian photoreceptor subtypes. J. Comp. Neurol. 523:649–668, 2015. © 2014 Wiley Periodicals, Inc.
Frontispiece: Effective Surface Functionalization of Carbon Fibers for Fiber/Polymer Composites with Tailor‐Made Interfaces
Authors: Shiba Kota , Tagaya Motohiro , Samitsu Sadaki , Motozuka Satoshi 
Published: October 2014

AbstractComposites between carbon fibers (CFs) and heterogeneous materials have been widely studied and their fabrication techniques have been developed. However, their hydrophobic surfaces make it difficult to disperse CFs into hydrophilic resins, which results in weak junctions with ceramics. To develop high‐strength composite fibers, it is important to design interfacial chemical bonds. Thus, surface‐modification techniques of CFs have recently become the main focus and their interfaces have been characterized by various analytical methods. In this Minireview, various techniques that modify the CF surface by coating with inorganic polymers (metal oxide compounds) are highlighted, and the applications of novel nanocomposite fibers are also described. Furthermore, interfacial bonds between CFs and polymer resins are reviewed and discussed in terms of CF‐reinforced plastics and their future prospects.
Frontispiece: Self‐Organization of Polar Porphyrinoids
Authors: Babu Sukumaran Santhosh , Bonifazi Davide 
Published: October 2014

AbstractThis Minireview focuses on the very recent developments in the field of porphyrin‐based self‐assembled nanomaterials with a particular focus on the use of tetrapyrrolic macrocycles bearing amphiphilic and ionic functionalities. As one of the most studied molecular materials, the importance of porphyrin‐derived nanomaterials has attracted wide interest in many applications like catalysis, photodynamic therapy, and organic solar cells to name a few. By using key examples that have recently appeared in the literature, the discussion unfolds through two sections: amphiphilic and ionic assemblies. Although it focuses on the nanostructuring methodologies used to obtain organized materials, the discussion will also target the physical characterization of the functional materials for their implementation in prototypes.
Frontispiece: Ferrofluids: Synthetic Strategies, Stabilization, Physicochemical Features, Characterization, and Applications
Authors: Joseph Aswathy , Mathew Suresh 
Published: October 2014

AbstractFerrofluids (FFs) or magnetic nanofluids are incredible smart materials consisting of ultrafine magnetic nanoparticles suspended in a liquid carrier medium, which exhibit both fluidity and magnetic controllability. Studies involving the dynamics and physicochemical properties of these magnetic nanofluids are an interdisciplinary area of research attracting researchers from different fields of science and technology. Herein, a comprehensive Review on the different aspects of FF research is presented. First, the synthesis and stabilization of various types of FFs are discussed followed by their physicochemical features such as polydispersity, magnetic behavior, dipolar interactions, formation of chainlike aggregates, and long‐range ordering. The Review also details the rheological and thermal properties, dynamic instabilities, phase behavior, and particle assemblies in FFs to form complex multipolar geometries, photonic nanostructures, labyrinth structures, thin films, and droplets. Many important characterization techniques for probing FF properties are also briefly discussed, and the numerous innovative applications and future prospects of FFs are outlined.