bluuebunny/crossref_metadata_2025_split huggingface dataset:
Electrochemical Deposition and Spectroelectrochemical Response of Bromophenol Blue Films on Gold
Authors: Saydjari A. , Pietron J. J. , Simpkins B. S. 
Published: May 2015

AbstractBromophenol blue (BPB) was electropolymerized onto a Au substrate. The effects of voltammetric cycle number, BPB concentration, and pH on film thickness, density, optical absorption, and electrochemical susceptibility were evaluated, and favorable deposition conditions were identified. Quantitative measurement of the film mass via quartz crystal microbalance enabled determination of the molar volume and revealed a strong dependence of film density with deposition pH. Finally, electrochemical control of the optical properties of BPB films was demonstrated via in situ spectroelectrochemistry. We believe this is the first demonstration of electropolymerization of pure BPB on Au, and thus the first demonstration of poly(BPB) as an electrochemically switchable optical coating.
Biotic ligand modeling approach: Synthesis of the effect of major cations on the toxicity of metals to soil and aquatic organisms
Authors: Ardestani Masoud M. , van Straalen Nico M. , van Gestel Cornelis A. M. 
Published: May 2015

Abstract

The biotic ligand model (BLM) approach is used to assess metal toxicity, taking into account the competition of other cations with the free metal ions for binding to the biotic ligand sites of aquatic and soil organisms. The bioavailable fraction of metals, represented by the free metal ion, is a better measure than the total concentration for assessing their potential risk to the environment. Because BLMs are relating toxicity to the fraction of biotic ligands occupied by the metal, they can be useful for investigating factors affecting metal bioaccumulation and toxicity. In the present review, the effects of major cations on the toxicity of metals to soil and aquatic organisms were comprehensively studied by performing a meta-analysis of BLM literature data. Interactions at the binding sites were shown to be species- and metal-specific. The main factors affecting the relationships between toxicity and conditional binding constants for metal binding at the biotic ligand appeared to be Ca2+, Mg2+, and protons. Other important characteristics of the exposure medium, such as levels of dissolved organic carbon and concentrations of other cations, should also be considered to obtain a proper assessment of metal toxicity to soil and aquatic organisms. Environ Toxicol Chem 2015;34:2194–2204. © 2015 SETAC
The metabolomics of asthma control: a promising link between genetics and disease
Authors: McGeachie Michael J. , Dahlin Amber , Qiu Weiliang , Croteau‐Chonka Damien C. , Savage Jessica , Wu Ann Chen , Wan Emily S. , Sordillo Joanne E. , Al‐Garawi Amal , Martinez Fernando D. , Strunk Robert C. , Lemanske Robert F. , Liu Andrew H. , Raby Benjamin A. , Weiss Scott , Clish Clary B. , Lasky‐Su Jessica A. 
Published: May 2015

AbstractShort‐acting β agonists (e.g., albuterol) are the most commonly used medications for asthma, a disease that affects over 300 million people in the world. Metabolomic profiling of asthmatics taking β agonists presents a new and promising resource for identifying the molecular determinants of asthma control. The objective is to identify novel genetic and biochemical predictors of asthma control using an integrative “omics” approach. We generated lipidomic data by liquid chromatography tandem mass spectrometry (LC‐MS), ­ using plasma samples from 20 individuals with asthma. The outcome of interest was a binary indicator of asthma control defined by the use of albuterol inhalers in the preceding week. We integrated metabolomic data with genome‐wide genotype, gene expression, and methylation data of this cohort to identify genomic and molecular indicators of asthma control. A Conditional Gaussian Bayesian Network (CGBN) was generated using the strongest predictors from each of these analyses. Integrative and metabolic pathway over‐representation analyses (ORA) identified enrichment of known biological pathways within the strongest molecular determinants. Of the 64 metabolites measured, 32 had known identities. The CGBN model based on four SNPs (rs9522789, rs7147228, rs2701423, rs759582) and two metabolites—monoHETE_0863 and sphingosine‐1‐phosphate (S1P) could predict asthma control with an AUC of 95%. Integrative ORA identified 17 significantly enriched pathways related to cellular immune response, interferon signaling, and cytokine‐related signaling, for which arachidonic acid, PGE2 and S1P, in addition to six genes (CHN1, PRKCE, GNA12, OASL, OAS1, and IFIT3) appeared to drive the pathway results. Of these predictors, S1P, GNA12, and PRKCE were enriched in the results from integrative and metabolic ORAs. Through an integrative analysis of metabolomic, genomic, and methylation data from a small cohort of asthmatics, we implicate altered metabolic pathways, related to sphingolipid metabolism, in asthma control. These results provide insight into the pathophysiology of asthma control.
Is It Really Love? A Comparative Investigation of the Emotional Nature of Brand and Interpersonal Love
Authors: Langner Tobias , Schmidt Jennifer , Fischer Alexander 
Published: May 2015

ABSTRACTThe use of interpersonal love theories is standard in brand love research. Yet no empirical evidence exists to confirm the equivalence of the emotional nature of these forms of love, which is required to justify the transfer of theories and measures from interpersonal to brand love settings. Building on dimensional emotional theories, this study compared the emotional nature of brand love against interpersonal love, interpersonal liking, and brand liking, using a mixed‐method approach. Qualitative Study 1 revealed emotional differences and similarities between the two love constructs; in particular, unlike interpersonal love, brand love was driven by rational benefits, such as product quality. Study 2 combined physiological and pictographic measures to show that brand love was less arousing than interpersonal love, though loved brands can be as arousing as close friends and induce more positive valence than this interpersonal relationship. According to dimensional emotional theories, interpersonal love and brand love thus differ, and researchers require prudence before transferring interpersonal love theories and scales directly to brand love research, without accounting for differences in the emotional nature of brand love and interpersonal love.
Drivers and Outcomes of Green Tourist Attitudes and Behavior: Sociodemographic Moderating Effects
Authors: Leonidou Leonidas C. , Coudounaris Dafnis N. , Kvasova Olga , Christodoulides Paul 
Published: May 2015

ABSTRACTThis article reports the findings of a study, conducted among 234 foreign tourists who visited Cyprus, that aimed to identify the drivers and outcomes of eco‐friendly attitudes and behavior. Using structural equation modeling, the authors confirmed that deontological status, law obedience, and political action of tourists positively influence the adoption of an environmentally friendly attitude. In turn, these effects are conducive to eco‐friendly behavior, which ultimately enhances tourist satisfaction. Certain sociodemographic characteristics of tourists—namely, gender, age, education, and income—had a moderating effect on the link between deontological status, law obedience, and political action on the one hand and eco‐friendly attitudes on the other hand. Tourist nationality also had a control effect on tourist eco‐friendly attitudes.
Effect Symmetry of Benefit Criteria in Postpurchase Evaluations
Authors: Lee Dong‐Jin , Yu Grace B. , Merunka Dwight R. , Bosnjak Michael , Sirgy M. Joseph , Johar J. S. 
Published: May 2015

ABSTRACTThis research proposes a theoretical model of postpurchase evaluations that incorporates seven sets of benefits: functional, symbolic, economic, safety, hedonic, moral, and leisure benefits. These benefit criteria are well documented in the literature. The study reported here was designed to test the effect symmetry of these benefit criteria in postpurchase evaluations. Effect symmetry refers to whether increases in a benefit are likely to cause proportional increases in postpurchase evaluations. The study tested the hypothesis that “must‐have” benefits (functional, economic, and safety benefits) are negatively asymmetric, whereas the “nice‐to‐have” benefits (symbolic, hedonic, moral, and leisure benefits) are positively symmetric. Five surveys were conducted in relation to five product categories in four countries (computers and automobiles in the United States, banks in France, housing in Korea, and leisure travel in Germany). Respondents completed 2386 questionnaires, of which 2291 were used in the statistical analysis. With respect to effect symmetry, the results indicate that the criterion of functional benefits is negatively asymmetric in predicting postpurchase evaluations, whereas symbolic and moral benefits are positively asymmetric. Hedonic and leisure benefits are symmetric. Managerial implications are discussed.
Disclosure of research results in genetic studies of Parkinson's disease caused byLRRK2mutations
Authors: Pont‐Sunyer Claustre , Bressman Susan , Raymond Deborah , Glickman Amanda , Tolosa Eduardo , Saunders‐Pullman Rachel 
Published: May 2015

AbstractWith the advent of large genetic studies examining both symptomatic and asymptomatic individuals, whether and how to disclose genetic research results have become pressing questions. The need is particularly acute in the case ofLRRK2research: Movement centers worldwide are recruiting cohorts of individuals with Parkinson's disease (PD) and their family members, including asymptomatic carriers. Clinical features and treatment are complex and evolving, and disclosure policies vary at different sites and have been modified during the course of some studies. We present the major ethical principles of autonomy, beneficence, nonmaleficence, and honesty that should guide disclosure policies in studies of families withLRRK2mutations. We make recommendations regarding genetic counseling, policies of either active or passive disclosure, responsibilities of funders to budget for genetic counseling, clinical genetic testing where locally required for disclosure, and aspects of study design to avoid mandatory disclosure whenever feasible. © 2015 International Parkinson and Movement Disorder Society
Virtually Designed Triclosan‐Based Inhibitors of Enoyl‐Acyl Carrier Protein Reductase of Mycobacterium tuberculosis and of Plasmodium falciparum
Authors: Owono Owono Luc C. , Ntie‐Kang Fidele , Keita Melalie , Megnassan Eugene , Frecer Vladimir , Miertus Stanislav 
Published: May 2015

AbstractWe report here new chemical structures of predicted nanomolar triclosan‐based inhibitors (TCLs) of Mycobacterium tuberculosis enoyl‐acyl carrier protein reductase (InhA) virtually proposed by computer‐assisted molecular design. 3D models of InhA‐TCL complexes were prepared by in situ modifications of the reference crystal structure (PDB entry 1P45) for a training set of 15 TCLs with known InhA inhibitory activities. A QSAR model was built leading to linear correlation between the calculated free energies of complexation (ΔΔGcom) and experimental values IC50exp: pIC50=−0.0657×ΔΔGcom+3.0502, R2=0.96. In addition, ligand‐based quantitative pharmacophore model (PH4) was built from bound conformations of the training set compounds and confirmed the correlation between molecular models and observed activities: pIC50exp=0.8929×pIC50pre−0.441, R2=0.95. Structural information from both models helped us to propose new TCL analogues. A virtual library of TCLs with known predicted activities against enoyl‐acyl carrier protein reductase of Plasmodium falciparum (PfENR) was evaluated, revealing dual target TCLs. Moreover, analysis of binding site interactions suggested enriching substitutions, which led to more potent TCLs with predicted pIC50pre as low as 7 nM. The computational approach, which used both free energy estimated from molecular modeling and 3D‐QSAR pharmacophore model, was helpful in virtually proposing the dual‐targeted drugs and provided valuable information for the design of novel potential antituberculotic agents.
Fast iterative pre‐emphasis calibration method enabling third‐order dynamic shim updated fMRI
Authors: Fillmer Ariane , Vannesjo Signe Johanna , Pavan Matteo , Scheidegger Milan , Pruessmann Klaas Paul , Henning Anke 
Published: May 2015

PurposeTo calibrate a pre‐emphasis to sufficiently compensate eddy currents for application of dynamic shim updating to fMRI without extension of scan times.MethodsEddy current effects induced into all shim terms up to third‐order were characterized by spatiotemporal field monitoring, using a third‐order field camera. Pre‐emphasis settings were derived from the measurements and iteratively evaluated and refined. The calibrated pre‐emphasis was applied to slice‐wise dynamic shim updating in combination with a dynamic excitation frequency (F0) determination and a slice‐wise B0 optimization routine for in vivo echo planar imaging and resting‐state functional MRI.ResultsThe described method for pre‐emphasis calibration led to settling times of remaining eddy current effects below 2 ms, allowing for the application of dynamic shim updating to fMRI without extension of scan times or induction of eddy current related artifacts. A dynamic F0 determination compensates frequency shifts induced by the superposition of different shim fields, and therefore, prevents an image shift within the field of view. Hardware limitations necessitate the reduction of the maximum applicable B0 shim field amplitudes and restrict the shim performance.ConclusionThe proposed method enables accurate pre‐emphasis calibration, and therefore, the application of dynamic shim updating to fMRI. Magn Reson Med 75:1119–1131, 2016. © 2015 Wiley Periodicals, Inc.
An improved moving‐least‐squares reconstruction for immersed boundary method
Authors: Li Dong , Wei Anyang , Luo Kun , Fan Jianren 
Published: May 2015

SummaryThe current work presents an improved immersed boundary method based on the ideas proposed by Vanella and Balaras (M. Vanella, E. Balaras, A moving‐least‐squares reconstruction for embedded‐boundary formulations, J. Comput. Phys. 228 (2009) 6617–6628). In the method, an improved moving‐least‐squares approximation is employed to build the transfer functions between the Lagrangian points and discrete Eulerian grid points. The main advantage of the improved method is that there is no need to obtain the inverse matrix, which effectively eliminates numerical instabilities caused by matrix inversion and reduces the computational cost significantly. Several different flow problems (Taylor‐Green decaying vortices, flows past a stationary circular cylinder and a sphere, and the sedimentation of a free‐falling sphere in viscous fluid) are simulated to validate the accuracy and efficiency of the method proposed in the present paper. The simulation results show good agreement with previous numerical and experimental results, indicating that the improved immersed boundary method is efficient and reliable in dealing with the fluid–solid interaction problems. Copyright © 2015 John Wiley & Sons, Ltd.
A Practical One‐Pot Synthesis of Positron Emission Tomography (PET) Tracers via Nickel‐Mediated Radiofluorination
Authors: Zlatopolskiy Boris D. , Zischler Johannes , Urusova Elizaveta A. , Endepols Heike , Kordys Elena , Frauendorf Holm , Mottaghy Felix M. , Neumaier Bernd 
Published: May 2015

AbstractRecently a novel method for the preparation of 18F‐labeled arenes via oxidative [18F]fluorination of easily accessible and sufficiently stable nickel complexes with [18F]fluoride under exceptionally mild reaction conditions was published. The suitability of this procedure for the routine preparation of clinically relevant positron emission tomography (PET) tracers, 6‐[18F]fluorodopamine (6‐[18F]FDA), 6‐[18F]fluoro‐l‐DOPA (6‐[18F]FDOPA) and 6‐[18F]fluoro‐m‐tyrosine (6‐[18F]FMT), was evaluated. The originally published base‐free method was inoperative. However, a “low base” protocol afforded protected radiolabeled intermediates in radiochemical conversions (RCCs) of 5–18 %. The subsequent deprotection step proceeded almost quantitatively (>95 %). The simple one‐pot two‐step procedure allowed the preparation of clinical doses of 6‐[18F]FDA and 6‐[18F]FDOPA within 50 min (12 and 7 % radiochemical yield, respectively). In an unilateral rat model of Parkinsons disease, 6‐[18F]FDOPA with high specific activity (175 GBq μmol−1) prepared using the described nickel‐mediated radiofluorination was compared to 6‐[18F]FDOPA with low specific activity (30 MBq μmol−1) produced via conventional electrophilic radiofluorination. Unexpectedly both tracer variants displayed very similar in vivo properties with respect to signal‐to‐noise ratio and brain distribution, and consequently, the quality of the obtained PET images was almost identical.
Consideration on formation mechanism of aromatic polyamide hollow spheres prepared by reaction‐Induced phase separation
Authors: Nakayama Hirofumi , Fujitsu Yuji , Uchida Tetsuya , Yamazaki Shinichi , Kimura Kunio 
Published: May 2015

ABSTRACTHollow spheres of poly(1,4‐phenylene‐5‐hydroxyisophthalamide) had been obtained by the reaction‐induced phase separation during polymerization of 5‐hydroxyisophthalic acid and 1,4‐phenylene diamine in an aromatic solvent. In this study, formation mechanism of the hollow spheres was considered from the view points of eliminated small molecules, polymer structure, and cross‐linking reaction. With respect to the eliminated small molecules, water was the most desirable to form gas‐bubbles in droplets compared with methanol and acetic acid, due to the insolubility into the polymerization system. Rigid polymer structure was also needed to prepare hollow spheres owing to the rapid solidification of droplets. Further, phenolic hydroxyl group in 5‐hydroxy‐1,3‐phenylene moiety caused the ester‐amide exchange reaction to form cross‐linked skin layer in the droplets. The efficient formation of the skin layer was important to encapsulate gas‐bubbles in the droplets, resulting in the formation of hollow structure. © 2015 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2015, 53, 1966–1974
Kinetic study of MOCVD of NiO films from bis‐(ethylcyclopentadienyl) nickel
Authors: Kondrateva A. S. , Mishin M. , Shakhmin A. , Baryshnikova M. , Alexandrov S. E. 
Published: May 2015

AbstractNiO films were grown by metal‐organic chemical vapor deposition (MOCVD) using bis‐(ethylcyclopentadienyl) nickel [(EtCp)2Ni] and oxygen or ozone as precursors. The kinetic regularities of MOCVD processes were experimentally studied in the deposition temperature range 600‐820 K for the reaction systems: (EtCp)2Ni–O2–Ar and (EtCp)2Ni–O3–O2–Ar. The results obtained show that the deposition processes in the temperature range 600‐700 K are controlled by kinetics and the value of activation energy of the processes is 80±5 kJ·mol−1 in both cases. The growth process in the temperature region 700–840 K is controlled by mass transport. An introduction of ozone in the reaction gas phase led to nearly twofold decrease of deposition rate probably because of homogeneous reactions with (EtCp)2Ni. (© 2015 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
CVD synthesis and catalytic combustion application of chromium oxide films
Authors: Liang Jing , Pan Guan‐Fu , Fan Shi‐Bin , Cheng Wei‐Liang , Tian Zhen‐Yu 
Published: May 2015

AbstractChromiumoxide (Cr2O3) thin films were controllably synthesized by pulsed‐spray evaporation chemical vapor deposition (PSE‐CVD) for deep oxidation of propene. The effect of substrate temperature on the growth kinetics and morphology of the films was investigated. The prepared samples were comprehensively characterized with respect to structure, morphology and surface composition with XRD, SEM and XPS, respectively. An in situ diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS) was involved to reveal the surface mechanism occurred on Cr2O3. The growth rate exhibited a linear behavior when the temperature increase from 300 to 450 °C. The structural analysis indicated that a pure phase of Cr2O3 was obtained at 425 °C. The catalytic tests showed that Cr2O3 films prepared on flexible substrates exhibited advantages for the catalytic oxidation of C3H6. Based on the DRIFTS observations, the Langmuir‐Hinshelwood (L‐H) mechanism was proposed for C3H6 over Cr2O3 films. (© 2015 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Die neue Straßenbrücke in Toruń, Polen – Teil 2: Nachweise
Authors: Malinowski Maciej , Banaś Anna , Cywiński Zbigniew , Wąchalski Krzysztof 
Published: May 2015

AbstractAls Fortsetzung von Teil 1 [1], der über den Entwurf und den Bau der neuen, die Weichsel querenden Straßenbrücke in Toruń (deutsch: Thorn) berichtet, geht es im Folgenden um die theoretischen und experimentellen Nachweise zum Montageprozess und zu Probebelastungen. Somit ist eine umfassende Beurteilung der beschriebenen, herausragenden Ingenieursleistung gegeben.The new road bridge in Toruń, Poland – Part 2: structural design calculation. As a continuation of part 1 [1], which represents the design and the construction of the road bridge crossing the river Vistula in Toruń (Thorunium), now it will be turned over to the theoretical and experimental procedures that have been applied in the mentioned bridge mounting and load tests. Consequently, a full judgement of the mentioned outstanding engineer achievement is available.
Schubtragfähigkeit und M‐V‐Interaktion von Flachdecken mit integrierten hohlkastenförmigen Stahlprofilen
Authors: Schäfer Markus 
Published: May 2015

AbstractFlachdecken mit integrierten Stahlprofilen in Verbundbauweise zeichnen sich vor allem durch die schlanke Bauweise mit geringen Deckenhöhen aus. In den letzten Jahren haben sich neben den typischen Querschnitten aus gewalzten Profilen mit untergeschweißter Gurtplatte immer mehr hohlkastenähnliche Profilformen durchgesetzt. Bei diesen Systemen kann zur Steigerung der Querkrafttragfähigkeit ein hybrides Fachwerkmodell abgeleitet werden, bei dem neben der Querkrafttragfähigkeit des Stahlprofils auch die Tragfähigkeit des Betons angerechnet wird. Aufgrund der daraus resultierenden zusätzlichen Spannungen im Stahlprofil muss die Momenten‐Querkraft‐Interaktionsbeziehung erweitert werden.Shear resistance and M‐V‐Interaction of Slim‐Floor‐systems with integrated steel‐box sections – Approach of a hybrid truss model for the shear design. Shallow‐floor slabs with integrated steel profiles in composite behavior are mainly characterized by the slim design. Parallel to the traditional sections consisting of rolled profiles with an additional bottom plate also floor‐slabs with integrated steel‐box sections have gained widespread adoption in practice in the recent years. Because of the sheathing of the concrete by the steel section a hybrid truss model with a compression strut in the concrete section is developed, increasing the shear resistance of these sections. Due to the additional steel stresses resulting by the truss model, the relationship for the interaction between moment and vertical shear forces is to expand.