bluuebunny/crossref_metadata_2025_split huggingface dataset:
Istikhdām Al-Tharīqah Al-Tarkībiyyah Li Tarqiyah Mahārah Al-Qira’ah Wa Al-Kitābah Ladā Tullāb Al-Shaff Al-Sābi’ Bi Al-Madrasah Al-Mutawassithah Pesantren Alhikmah 2 Cirebon
Authors: Gunawan Wawan 
Published: August 2024

Tujuan dari penelitian ini adalah untuk mengetahui keterampilan membaca dan menulis siswa kelas eksperimen dan kelas kontrol di SMP Pesantren Al-Hikmah 2 Cirebon sebelum dan sesudah pembelajaran, dan untuk mengetahui pengaruh penggunaan metode Tarkibiyah dalam meningkatkan keterampilan membaca dan menulis siswa SMP Pesantren Al-Hikmah 2 Cirebon. Pendekatan yang digunakan dalam penelitian ini adalah pendekatan kuantitatif dan menggunakan metode quasi eksperimen dengan desain pretest posttest kelompok. Hasil penelitian menunjukkan bahwa: (1) Keterampilan membaca siswa sebelum pembelajaran pada kelas eksperimen dan control menujukkan hasil rata-rata 42,96 masuk kategori cukup. Keterampilan menulis pada sebelum pembelajaran pada kelas eksperimen dan control masuk kategori “kurang” dengan nilai rata-rata 37,78 (2) Keterampilan membaca siswa sesudah pembelajaran pada kelas eksperimen dan control menunjukkan peningkatan hasil masuk kategori baik. Keterampilan menulis siswa sesudah pembelajaran pada kelas eksperimen menunjukkan peningkatan hasil dan masuk kategori baik. (3) Hasil nilai N-Gain (dalam persentase) pada keterampilan membaca dan keterampilan menulis siswa kelas eksperimen menunjukkan pembelajaran menggunakan metode Tarkibiyah “cukup efektif” dalam meningkatkan keterampilan membaca dan keterampilan menulis siswa. Dengan demikian, maka terdapat pengaruh penggunaan metode Tarkibiyah dalam meningkatkan keterampilan membaca dan menulis siswa SMP Pesantren Al-Hikmah 2 Cirebon.
The strategic use of engagement resources in engineering written reports
Authors: Simpson-Smith Claire 
Published: August 2024

Written engineering discourse is embedded in its social context and is sensitive to the relationship between an engineer and their client. In order for engineering writers to be able to frame their evidence as part of a convincing argument, they require a strong understanding of the client’s needs and the regulatory context. To present this understanding and framing in writing, the grammatical resources covered by the ENGAGEMENT framework (Martin and White, 2005) are crucial. Engagement resources offer the tools with which to position the voice of the writer in relation to the reader and other voices. This paper presents the findings of a study of the use of engagement resources in a corpus of professional engineering texts which are being used in a larger project investigating the persuasive discourse of engineering. The results indicate that engineering writers strategically manipulate the contraction and expansion of the discourse space in accordance with the purpose of the text, the nature of the evidence and their particular persuasive stance. This manipulation either opens or closes the amount of room afforded to the reader to disagree with the propositions presented. Engagement meanings are also graded to increase likelihood of success and downplay negative perceptions. Finally, engagement resources are selected in such a way to present an impression of objectivity in the writing style. These findings have implications for the teaching of writing to engineering students.
Face- and content validity of the University of the Free State In-Hand Manipulation Assessment Instrument (UFS IHMAI) for children in South Africa
Authors: Visser Marieta , Nel Riette , Van Aswegen Nicke , Basson Jana , Lochner Chante 
Published: August 2024

Introduction: No standardised assessment instrument that covers all the components of in-hand manipulation (IHM) with evidence of instrument development and psychometric properties appropriate for South African children is currently available for occupational therapists. The University of the Free State In-Hand Manipulation Assessment Instrument (UFS IHMAI) is in the process of development to gain recognition as a standardised assessment instrument for children in South Africa. This article reports on the first and second stages of the face- and content validation process of the UFS IHMAI.
Method: A quantitative descriptive study design with a convenient sampling method was used. Participants provided their expert judgment by completing an EvaSys© online questionnaire.
Results: Fifty-five occupational therapists with experience in paediatric hand function, and registered with the HPCSA and OTASA participated. The participants agreed (above 80% consensus) that the instrument's content is relevant and representative to assess all components (separately and as a whole) of IHM that it was intended to measure. Participants' comments and practical recommendations will form an important knowledge-base for the instrument developers to use in the third stage of content validity, namely revising and refinement.
Conclusion: The results confirmed the face- and content validity of the UFS IHMAI and supported the further development and psychometric testing of the assessment instrument for children in South Africa.

Implications for practice:
This article builds upon prior studies in which therapists in South Africa have recognised the necessity for an in -hand-maniputation (IHM) assessment. It offers a concise overview of instrument development theory and delineates the iterative process employed in developing the first draft of the University of the Free State In-Hand Manipulation Assessment Instrument (UFS IHMAI). Additionally, this article furnishes background details regarding the proposed instrument's content, administration, and scoring guidelines. It also incorporates therapists’ perspectives as end-user, providing informed perceptions and consensus on the content validity of the proposed instrument. The suggestions provided by the participating therapist working within the South African context can be employed by the researchers to inform the revision, reconstruction, and refinement of the instrument. Subsequently, the revised version will undergo another round of content validity testing (with experts in instrument development, and in the field) and other psychometric testing. As instrument development is an iterative and ongoing refinement process, the implication of this research might only become apparent after further studies.
CRESCIMENTO ECONÔMICO E DESENVOLVIMENTO NAS REGIÕES METROPOLITANAS DO BRASIL
Authors: Leite Helena de Oliveira , Ferrera de Lima Jandir 
Published: August 2024

O objetivo desta pesquisa foi analisar a convergência do crescimento e do desenvolvimento socioeconômico das regiões metropolitanas (RMs) brasileiras no período de 2005 e 2016. Para tanto, empregou-se a metodologia dos coeficientes de variação com o intuito de identificar a convergência de renda e desenvolvimento socioeconômico entre os municípios das RMs. A comparação entre as RMs seguiu dois parâmetros: a convergência de crescimento econômico ou renda; e a convergência do desenvolvimento socioeconômico. Para a análise da convergência do crescimento econômico foram utilizadas como variáveis: o PIB per capita geral e por setor econômico (primário, secundário e terciário), estimado a partir do Valor Adicionado Bruto, enquanto para o desenvolvimento socioeconômico utilizou-se como parâmetro o Índice Firjan de Desenvolvimento Municipal (IFDM) em suas três dimensões: emprego e renda, saúde e educação. Os resultados apontaram para o crescimento do PIB per capita em todas as RMs brasileiras, com maior concentração nas Regiões Centro-Oeste e Sul. O perfil do desenvolvimento socioeconômico também apresentou crescimento em todas as regiões, com maior concentração nas dimensões Saúde e Educação, porém com maior disparidade na dimensão Emprego e Renda.
From crisis to coping: Exploring the psychosocial impact of COVID-19 on primary school children in developing country
Authors: Elmuttalut Mohammed 
Published: August 2024

Primary school children are relatively vulnerable to the COVID-19 infection and its impact. This study aimed to assess the impact of COVID-19 on the psychosocial well-being of primary school children. This was a descriptive cross-sectional study from March-August 2021. A sample of 285 children was randomly assigned by cluster random sampling. Children were interviewed using a pretested and validated questionnaire. The questionnaire is composed of questions related to demographic information and the psychosocial impact of COVID-19 on primary school children. Children’s responses were scored, and descriptive analyses were conducted with SPSS version 25.0 (IBM SPSS Statistics). A total of 285 primary school children were interviewed. Children’s mean age was 13.2 ± 0.9 years old; 65.3% were males, 84.6% were from public schools, and 78.2% were in grade/class 8. 175 (61.4%) of participants reported that their daily lives had been disrupted by the COVID-19 pandemic, while 176 children (61.8%) avoided visiting crowded places; 59 children (20.7%) did not visit their friends, 90 children (31.6%) avoided public places, and 194 (68.1%) reported keeping their distance from people with influenza-like symptoms. COVID-19 had a profound impact on the psychosocial well-being of primary school children. Addressing the gaps in children's understanding of COVID-19 and promoting proactive health behaviors through targeted education can significantly contribute to mitigating the psychosocial impact of COVID-19 on the primary school population. Future research and efforts to prioritize the appropriate strategies to mitigate the impact of COVID-19 on primary school children are extremely needed.
Isolation and identification of endophytic fungi from ocimum sanctum
Authors: Bhonsle Kaina Bhonsle 
Published: August 2024

In this study, we aimed to isolate and identify endophytic fungi from the Ocimum sanctum plant, commonly known as Holy Basil and Hindi name- Tulsi. 1. To investigate the endophytic mycobiota from Ocimum sanctum. 2. To isolate and identify some endophytic fungi in selected medicinal plant. 3. To study phenotypic characteristics of endophytic fungi in selected medicinal plant. Methods employed for the isolation and identification of endophytic fungal strains encompassed a multi-step approach, involving surface sterilization, tissue maceration, and subsequent fungal isolation. Morphological and microscopic characterization were utilized to identify the isolated fungal strains. As a result, a total of five distinct endophytic fungal strains were successfully isolated and identified. The results revealed a high diversity of endophytic fungi associated with Ocimum sanctum. Furthermore, several potential bioactive compounds were detected in the isolated fungi, further emphasizing their importance. This study contributes to the knowledge of endophytic fungi associated with Ocimum sanctum and provides a foundation for further investigation into their biotechnological potential.
Assessment of prescription pattern and cost effective analysis of oral hypoglycemic agents used in treatment of type 2 diabetes mellitus
Authors: Manapurthu Maha George , Deepashree C  , Pradeep Roopali , Nivedha Maria 
Published: August 2024

Diabetes mellitus treatment that is cost-effective not only ensures rational drug use but also lowers patient costs. When a cost-effectiveness tool is used correctly in therapeutic decision making, the disease's complications are reduced, and the patients' quality of life is improved. This study aims to evaluate the prescribing patterns and to carry out cost effective analysis for Oral Hypoglycaemic agents used in the treatment of Type 2 Diabetes Mellitus. A Prospective, observational study was carried out in the out-patient department of a Diabetes Specialty Centre-Bangalore for a period of 9 months. Individuals aged 18 and above and clinically diagnosed with T2DM with or without HTN and dyslipidaemia were considered eligible for the study. Individuals who were on Insulin for management and those with other types of Diabetes were excluded from the study. A total of 274 prescriptions were evaluated. The majority of the patients belonged to the age group of 60 years and older (55%). Prevalence of Diabetes were found to be more in men (53%) when compared to women (47%). Most of the study subjects were diagnosed with HTN + T2DM (35%) followed by T2DM+HTN+ Dyslipidaemia (27%). The average number of drugs per prescription were 2.04. It was observed that Sulphonylureas, Biguanides, Alphaglucosidase inhibitors, DPP-4 inhibitors, Thiazolidinediones and SGLT2 inhibitors were the numerous drugs prescribed to the study population. Incremental Cost Effectiveness Ratio (ICER) was calculated and it was found that DPP-4 inhibitors are cost effective in monotherapy while DPP-4 inhibitors+ Biguanides for double combination therapy and DPP-4 inhibitors+SGLT2 inhibitors + Biguanides in three combination was found to be cost effective. In our study, it was observed that Metformin was most commonly prescribed among the OHA and DPP-4 inhibitors are cost effective. Polypharmacy is a big issue, especially for the elderly population. This study provides the baseline data for carrying out further researches on prescription patterns as well as cost effective analysis including all costs in health care settings.
Implementasi Program Sekolah Ramah Anak dalam Membentuk Karakter Anak Usia Dini
Authors: Saadatul Kholidiyah  , Amala Nisael 
Published: August 2024

Penelitian ini bertujuan untuk mengetahui sejauh mana implementasi program sekolah ramah anak dalam membentuk karakter anak usia dini. Pendidikan ramah anak khususnya pada lembaga pendidikan anak usia dini, memberikan kesempatan agar anak dapat berkembang sesuai dengan potensi yang ada di dalam dirinya melalui fasilitas sarana dan prasarana yang mendukung, perencanaan pembelajaran yang sesuai dengan karakteristik anak dan mengembangkan karakter anak. Penelitian dilaksanakan di Lembaga RA Sunan Muria Poncokusumo Malang. Metode penelitian yang digunakan adalah metode kualitatif dengan teknik penggalian data dengan wawancara, observasi serta studi literatur. Hasil dari penelitian ini adalah dengan mengimplementasikan program sekolah ramah anak di Lembaga PAUD maka dapat membentuk karakter anak usia dini seperti positif seperti mandiri, disiplin, peduli lingkungan, berprestasi dan mampu menghargai prestasi yang ada pada diri peserta didik. Namun peneliti juga menemukan beberapa karakter yang perlu dioptimalisasi lagi seperti tanggung jawab jawab terhadap sampah sendiri
Desain Model Permainan Kreatif Tradisional Ramah Anak dalam Meningkatkan Kemampuan Kognitif Anak Usia Dini
Authors: St. Maria Ulfah  , Aris munandar  , Arifin Ahmad  
Published: August 2024

Adapun tujuan dari penelitian ini adalah untuk mengetahui bagaimana gambaran desain pengembangan model permainan kreatif tradisional untuk meningkatkan kemampuan kognitif anak usia dini. Metode yang digunakan dalam penelitian ini adalah metode kualitatif dengan menggunakan kuesioner dan wawancara sebagai instrumen penelitian. Hasil penelitian menunjukkan bahwa media pembelajaran khususnya mengenai permainan tradisional yang ada di TK dan minimnya kemampuan guru dalam mengemas permainan tradisional menjadi menarik di TK juga masih kurang. Rancangan model permainan kreatif tradidional dalam hal ini permainan makkabacciq dan permainan mamboi yang terdiri dari 10 anak didik diberikan stimulus dengan memodifikasi aturan main dan media yang sesuai dengan karateristik anak usia dini.
Kata Kunci : Permainan kreatif tradisional, kognitif
Dissociation Behavior of Methane Hydrate Inside Different Saturation Sediments in a Sustained Depressurization Process
Authors: Dong Shuang , Chen Mingkun , Tian Mengru , Zheng Jia-nan , Yang Mingjun , Song Yongchen 
Published: August 2024

Summary
Methane hydrate is one of the important energy storage sources, naturally distributed in marine porous sediments. However, the dissociation behavior of hydrate inside different saturation sediments during sustained depressurization remains unclear. In this study, methane hydrate-bearing sediments were synthesized using initial water saturations varying between 9.5% and 56.9% and subsequently dissociated at a gas exhaust rate of 0.77 Ls/min. The results indicate that the dissociation of hydrates is closely related to the initial hydrate distribution until the sediments get iced when the sediment pressure declines below 2.5 MPa. Due to the exothermic reaction of ice formation, the dissociation of hydrates after icing accelerates significantly, and its limiting factor becomes the gas exhaust rate. In addition, both production and monitoring pipes were used in this study to evaluate the possible plugging within the sediments, and the plugging zone within the sediments can be located by examining the thermodynamic correlation between pressure and temperature responses. It was found that all experimental cases with high saturations (47.4% and more initial water) easily induce plugging between sediments and production/monitoring pipes, with the maximum pressure gap reaching up to 2.5 MPa. These findings may aid in ensuring the safety and efficiency of the hydrate exploitation process in the future.
High-rate Biohydrogen Production in Single-Chamber Microbial Electrolysis Cell Using Iron-Sulfide Modified Biocathode
Authors: Qing Bu , Noori Md Tabish , Min Booki 
Published: August 2024

Abstract

Microbial electrolysis cells (MEC) can produce hydrogen (H2) at a low energy expense, but H2 production rate is often limited by poor microbe-electrode interaction. This study aimed to enhance the interaction of microbes with a cathode electrode modified with an iron-sulfide (FeS) catalyst in MECs to achieve an efficient hydrogen evolution reaction (HER) and to optimize performance at different substrate concentrations, ranging from 1 g/L to 3 g/L of glucose. The electrochemical analysis revealed FeS a highly active catalyst for HER, surpassing the performance of a 10% platinum (Pt-C)-modified cathode. At 2g/L glucose, MECs with a FeS-modified cathode (MEC-FeS) produced hydrogen at the highest yield of 7.01 mol H2/mol glucose, and the hydrogen production rate was 1.96 ± 0.09 m3/m3•d. The control operations of MEC with a pristine cathode and dark fermentation resulted in a reduced hydrogen yield of 5.83 ± 0.25 mol H2/mol glucose and 2.12 ± 0.1 mol H2/mol glucose, respectively. Moreover, the MEC-FeS achieved a high energy efficiency of 78 ± 5% when compared to the MEC without catalyst (60 ± 5%) and the dark fermentation (24 ± 1%). This study suggests that the utilization of FeS as a cathode catalyst in MECs can ensure high-rate hydrogen generation with optimal substrate concentration, paving the way for efficient upscaling and field application.
SARS-CoV-2 ORF3a accessory protein is a water-permeable channel that induces lysosome swelling
Authors: Michelucci Antonio , Sforna Luigi , Focaia Riccardo , Leonardi Maria Vittoria , Battista Angela Di , Rastelli Giorgia , Vespa Simone , Boncompagni Simona , Cristina Manlio Di , Catacuzzeno Luigi 
Published: August 2024

Abstract

Open reading frame 3a (ORF3a) is among the most expressed viral accessory proteins of SARS-CoV-2, the pathogen responsible for the last pandemic. ORF3a mainly targets lysosomes of the host cell and promotes lysosomal inactivation through their deacidification, an essential step for lysosomal exocytosis and virus egress. However, the exact mechanism through which ORF3a performs this function is still unclear. While seminal studies suggested ORF3a functioning as a cation-selective viroporin, a recent work disproved this conclusion. To unravel the possible function of ORF3a, here we employed a multidisciplinary approach including molecular dynamics (MD), molecular biology, electrophysiology, and electron microscopy. Our electrophysiological results, in accordance with apreliminary MD structural analysis, ruled out that ORF3a functions as anion channel when expressed in HEK293 cells. Conversely, both MD and videoimaging experiments for the assessment of cell volume changes demonstrated that ORF3a mediates the transmembrane transport of water. Using MD, we also identified the putative selectivity filter for water permeation, and experimentally confirmed its relevance for water transport by showing that its mutation at the level of an asparagine (N82L and N82W) abolishes ORF3a-mediated water permeation. Finally, ORF3a expression in HEK293 cells determined lysosomal volume increase (swelling), mitochondrial damage, and accumulation of intracellular membranes, and these effects were reverted by the N82W mutation. Collectively, our data suggest a new function for the ORF3a protein as a lysosomal water permeable channel. The ORF3a-mediated water transport across lysosome membrane might promote lysosomal swelling and deacidification and, by consequence, inactivation, a key step to promote virus egress from the cell.
Design of an Incremental Graph-based Routing Model for enhancing QoS of dense IoMT Networks using Truncated Side chains
Authors: Fuke Radhika , Ranawat Rekha 
Published: August 2024

Abstract

The exponential growth of Internet of Medical Things (IoMT) has necessitated the need for an efficient and secure routing mechanism capable of handling dense network traffic while also ensuring quality of service (QoS) and privacy. Existing solutions in the domain are often limited by their inability to effectively fuse temporal and spatial information for route optimization and lack comprehensive methods to secure route data samples. In this paper, I present the Incremental Graph-based Routing Model for QoS enhancement in dense IoMT Networks using Truncated Sidechains (IGRMQITS). Our model leverages a graph-based Q Learning (GQL) algorithm for route optimization, which is further enhanced using a novel Teacher Learner, based Firefly Optimizer (TLFFO). This ensures the identification of optimal routes by efficiently fusing temporal and spatial information of the nodes. To secure the data on these routes, we introduce an innovative truncated sidechaining model, which employs Grey Wolf Whale Optimizer (GWWO) for selecting optimal sidechain lengths. The chains are then truncated using a Fuzzy Analytic Hierarchy Process (AHP) that prioritizes different privacy levels, thereby ensuring a robust security mechanism for real-time networks. The proposed model has proven to significantly enhance the network performance, with a 10.5% reduction in communication delay, 8.5% increase in energy efficiency, 3.9% improvement in throughput, 1.5% increase in packet delivery ratio, and an 8.3% reduction in jitter. Furthermore, our model also excels in reducing the mining delay by 12.5%, cutting down energy consumption during mining by 5.9%, and decreasing the storage requirements for mining by 4.9%. Thus, IGRMQITS represents a significant step forward in the field of IoMT, addressing the critical challenges of route optimization, data security, and privacy in dense network environments. This work not only enhances the QoS in IoMT networks but also sets a new benchmark for future research in the domain, pushing the boundaries of what is possible in the field of IoMT network optimization and security levels.