bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Feasibility of the Initial Postsystolic to Systolic Strain Rate Ratio as a Predictor of the Viability of Ischemic Myocardium with Acute Myocardial Infarction
Authors: Park Soon Chang , Kang Ki‐Woon , Yoon Hyeon Soo , Myung Jin Cheol , Choi Yu Jeong , Park Sang Hyun , Jung Kyung Tae , Chin Jung Yeon 
Published: December 2013

BackgroundInvestigations of a strain index for the viability of ischemic myocardium with acute myocardial infarction (AMI) have been challenging. Therefore, the aim of this study was to evaluate patients with AMI to determine an optimal strain index for predicting the viability of ischemic myocardium.Methods and ResultsA total of 57 patients with AMI were assessed according to two‐dimensional (2D) speckle tracking imaging strain and strain rate (SR), measured during the acute phase before urgent revascularization and at a 1‐year follow‐up postrevascularization. During the acute phase, all the myocardial segments were classified according to the acute end‐systolic strain (Ses) values as normal (Ses ≤ −13%), hypocontractile (−13% < Ses ≤ −7%), or having a severe contractile abnormality (Ses > −7%). At the 1‐year follow‐up, we reassessed the recovery of the segments with a severe contractile abnormality. The viability of these segments was defined as an improved Ses (≤ −7%) at follow‐up postrevascularization. The Ses values, postsystolic strain index (PSI), and SR values were significantly better in the viable segments than in the nonviable segments at both the acute phase and at follow‐up (P < 0.001). The initial postsystolic to systolic SR ratio (SRps/SRs) had the best area under the curve (AUC = 0.897). In addition, a cutoff value of 0.6 predicted recovery from a severe contractile abnormality with a sensitivity of 75% and a specificity of 88%.ConclusionsThe initial SRps/SRs ratio identified the viability of ischemic myocardium with AMI; therefore, this novel index may be clinically useful in the treatment of patients with AMI.
Systolic Anterior Motion of the Posterior Leaflet in Hypertrophic Cardiomyopathy
Authors: Anderson Mark , Wayangankar Siddharth , Sivaram Chittur A. 
Published: December 2013

Mini‐AbstractAlthough isolated systolic anterior motion (SAM) of the posterior mitral valve leaflet has been previously documented in hypertrophic cardiomyopathy, this case highlights the therapeutic implications of diagnosing this phenomenon and the importance of meticulous echocardiographic techniques in these patients. We present a case of SAM of the posterior leaflet producing persistent dynamic left ventricular outflow tract obstruction despite septal myectomy and subsequent revision myomectomy in a patient with hypertrophic cardiomyopathy.
Creativity and Inequality: The Dual Path of China's Urban Economy?
Authors: Liu Cathy Yang , Xie Wen 
Published: December 2013

AbstractUtilizing Chinese data for the years of 1998, 2000, 2005, and 2008, this research traces the growth of the creative economy and the enlarging income inequality in China's urban economy. While the creative sector now makes up close to 30 percent of China's urban private employment, industry‐based earnings disparity has also increased substantively. Provinces with larger creative economy also tend to have higher level of wage inequality among workers of the creative sector, the working sector, and the service sector. Several other factors, especially internal migration flow, size of manufacturing, and ownership structure in local economy, are found to be significantly linked to inequality as well.
Effect of combined mutations in the enhancer II and basal core promoter of hepatitis B virus on development of hepatocellular carcinoma in Qidong, China
Authors: Qu Li‐Shuai , Zhu Jing , Liu Tao‐Tao , Shen Xi‐Zhong , Chen Tao‐Yang , Ni Zheng‐Pin , Ni Run‐Zhou , Lu Cui‐Hua 
Published: December 2013

AimTo investigate the roles of mutations in enhancer II (Enh II), basal core promoter (BCP) and precore (PC) regions of hepatitis B virus (HBV) in the progression of hepatocellular carcinoma (HCC) in Qidong, China.MethodsWe conducted a case–control study within a cohort of 2387 male HBV carriers who were recruited between August and September 1996. The HBV DNA sequence was determined in 152 HCC and 131 chronic hepatitis patients. Mutation exchanges during follow up in 115 cases were compared with 108 controls with serum samples taken during a similar length of follow up. In addition, a longitudinal study was conducted in 22 cases in which serial serum samples were available before HCC.ResultsAfter adjustment for age, history of cigarette smoking and alcohol consumption, hepatitis B e‐antigen positivity, T1653, V1753 and T1762/A1764 double mutations were associated with risk of HCC. Multivariate analysis showed that T1653, V1753 and T1762/A1764 double mutations were independent risk factors of HCC. Moreover, a significant biological gradient of HCC risk by number of mutations in Enh II/BCP regions was observed. Paired samples analysis indicated that the increased HCC risk for at‐risk sequence mutations were attributable to the persistence of these mutations, but not a single time point mutation. The longitudinal observation demonstrated a gradual combination of mutations in Enh II/BCP regions accumulated during the development of HCC.ConclusionT1653, V1753 and T1762/A1764 double mutations were independent risk factors of HCC. The effect of combined mutations in Enh II/BCP regions increased the risk and persistence of at‐risk sequence mutations and was critical for HCC development.
Associations between perceptions of evidence and adoption of H1N1 influenza infection prevention strategies among healthcare workers providing care to persons with spinal cord injury
Authors: Ullrich Philip M. , Lavela Sherri L. , Evans Charlesnika T. , Miskevics Scott , Weaver Frances M. , Goldstein Barry 
Published: December 2013

AbstractAimTo examine associations between perceptions of evidence (research evidence, clinical expertise, patient preferences) and outcomes of a nationwide programme to implement H1N1 influenza prevention guidelines.BackgroundHealthcare workers do not consistently adhere to recommended infection control practices and this may be associated with their perceptions of evidence sources.DesignCross‐sectional mailed survey.MethodA survey of healthcare workers was administered in August 2010 after implementation of H1N1 prevention guidelines. Outcomes of interest were ratings of adherence to H1N1 prevention guidelines.FindingsRespondents with complete data (N = 283) were included in analyses. Facility‐level adherence to guidelines was associated with opinions of clinical experts. Healthcare workers who rated clinical expertise as aligning with recommendations also rated their facilities as being more adherent to guidelines. Perceptions of research evidence and patient preferences were not associated with facility adherence. Personal adherence was not associated with perceptions of evidence, except among those healthcare workers who rated both clinical experts and patients as unsupportive of guidelines; these practitioners were less likely to adhere to recommended personal hygiene practices.ConclusionEfforts to implement guidelines might be most effective when capitalizing on the influence of clinical experts. To better explain variability in guideline adherence, inclusion of a broader array of variables is recommended for future studies.
Treatment of recalcitrant facial verrucae vulgares with sinecatechins (greentea catechins) ointment
Authors: Clouth A. , Schöfer H. 
Published: December 2013

AbstractBackgroundFacial verrucae vulgares are benign, but disfiguring skin manifestations of human papilloma virus infection. They are found as verrucae planae juveniles in young adults, but also as common warts in immunocompromised or atopic patients.ObjectiveTo find an alternative, non‐surgical treatment for a young man with atopic dermatitis and facial warts, who had not responded to 5‐FU ointment, waterfiltered infrared A (wIRA) irradiation and topical retinoids.MethodsTopical treatment with a sinecatechins 10% ointment (VeregenTM) as approved for genital warts thrice daily for 3 weeks in a 34‐year‐old man with atopic dermatitisResultsComplete remission of all facial warts was achieved within 20 days. Few side‐effects were observed (initially some light skin irritation only).ConclusionIn this case, topical sinecatechins proved to be a well‐tolerated and effective alternative to treat recalcitrant facial warts without surgery.
Bioactive and Biomimetic Restorative Materials: A Comprehensive Review. Part I
Authors: Jefferies Steven R. 
Published: December 2013

AbstractThe objective of this two‐part review article is to compare and contrast the composition, properties, and performance of the calcium silicate‐ and calcium aluminate‐based, bioactive dental materials, with an emphasis on the restorative applications of this evolving class of materials. Part I examines the development and application of the calcium silicate‐based materials ranging from dental materials derived from Portland cement to more recent materials based on further modifications of calcium silicate cement chemistry. Part II will consider the development, composition, properties, and application of the bioactive calcium aluminate‐based materials that have recently been developed for several indications in restorative dentistry.Clinical SignificanceBioactive materials have evolved over the past three decades from relatively specialized, highly biocompatible, but low‐strength dental materials to now emerge in product compositions for expanded clinical uses in restorative dentistry. Further developments to meet additional restorative clinical needs are anticipated in this newly emerging category of dental materials.
Hypodontia Prevalence over Four Decades in a Slovenian Population
Authors: Fekonja Anita 
Published: December 2013

AbstractAimThis study was performed to determine the prevalence of hypodontia of permanent teeth in the Slovenian population and whether such prevalence is associated with the year of birth.Material and MethodsThe prevalence of hypodontia in the Slovenian population, both male and female, and the association between tooth types, the upper or lower arch, the associated dental anomalies, and orthodontic treatment were studied using interviews and oral and panoramic radiographic examinations of 2,546 Slovenians born in years 1966, 1976, 1986, and 1996. The data were processed using Chi‐square test.ResultsAmong the 2,546 subjects studied, 307 teeth were missing in 175 subjects. The overall prevalence of hypodontia, excluding the third molars, was 6.9%; and there was no statistically significant difference with the year of birth. The most commonly missing teeth were the mandibular second premolar (38.8%), followed by the maxillary lateral incisors (32.6%). The majority (86.9%) of patients with hypodontia were missing only one or two teeth. Subjects with hypodontia (54.9%) were more often involved in orthodontic treatment than subjects without hypodontia (20.5%).ConclusionsThe relatively high prevalence of hypodontia and its frequent association with other dental anomalies emphasizes the importance of dental examination in early childhood with radiographic screening for hypodontia as standard public oral health policy.Clinical SignificanceThe relatively high prevalence of hypodontia in Slovenians and its frequent association with other dental anomalies emphasizes the importance of dental examination with radiographic screening of hypodontia in childhood as part of public oral health policy.
Esthetic Evaluation of Implants Placed after Orthodontic Treatment in Patients with Congenitally Missing Lateral Incisors
Authors: Mangano Carlo , Levrini Luca , Mangano Alessandro , Mangano Francesco , Macchi Aldo , Caprioglio Alberto 
Published: December 2013

AbstractObjectiveThe aim of this retrospective study was to evaluate the esthetic outcome of single tooth Morse taper connection implants used to replace congenitally missing lateral incisors after orthodontic treatment by means of the pink esthetic score (PES) and white esthetic score (WES) index.Materials and MethodsTwenty consecutive patients who were treated with a single tooth Morse taper connection implants (Leone Implant System®, Florence, Italy) were enrolled in this study. An independent calibrated examiner applied the PES/WES index to 20 implant‐supported restorations 3 months and 3 years after implant placement.ResultsNo implants were lost. All 20 implants fulfilled the established success criteria for dental implants with regard to osseointegration and prosthetic complications, with an overall implant‐crown success of 100.0%. At the 3 year examination, the mean distance between the implant shoulder and the first visible bone‐implant contact was of 0.49 ± 0.18 mm (95% confidence interval 0.41–0.57); the mean PES was 8.15 ± 1.69, and the mean WES was 8.70 ± 0.92.ConclusionsThe placement of single‐tooth Morse taper connection implants for rehabilitation of congenitally missing lateral incisors after orthodontic treatment represents a successful procedure in the medium term. Further studies are necessary in order to assess the long‐term esthetic score.Clinical SignificanceThis paper evaluates the esthetic outcome of Morse taper connection implants placed to restore congenitally missing lateral incisors after orthodontic treatment.
Space, Sovereignty, Inequality: Interpreting the Explosion of Brazil's VLS Rocket
Authors: Mitchell Sean T. 
Published: December 2013

ResumenEsse artigo explora narrativas produzidas a partir da explosão do foguete de lançamento de satélites (VLS) em 2003. A explosão causou a morte de 21 técnicos, mas, segundo alguns críticos, nunca foi devidamente explicada. Examino narrativas divergentes sobre a explosão que circulam entre grupos envolvidos, e analiso três representações de progresso e de desenvolvimento nacional implícitos: o nacionalista, o neoliberal, e o redistributivo. A importância do lançamento de satélites para o programa espacial brasileiro, as terríveis consequências da explosão, a obscuridade em torno das causas do evento, e a incerteza que marcou a investigação, fizeram do evento uma potente metonímia para as idéias de diferentes grupos sobre o Estado‐nação brasileiro, e suas futuros desejáveis e possíveis. Este trabalho também defende a importância da pesquisa etnográfica sobre a distribuição e os conflitos sobre a tecnociência, um ponto de inquérito importante para compreender a política da desigualdade global e de futuros imaginados.
Mining versus Oil Extraction: Divergent and Differentiated Environmental Subjectivities in “Post‐Neoliberal” Ecuador
Authors: Davidov Veronica 
Published: December 2013

ResumenEn el Ecuador postneoliberal la ecopolítica esta flanqueada entre la extracción petrolífera y la minería, siendo el primer caso un ejemplo del fracaso de las políticas neoliberales, mientras el segundo es reflejo de las promesas populistas. Este artículo analiza cómo en Intag el activismo antiminería refleja este cambio en las políticas neoliberales desde un estado petrolero a un estado “nuevo y progresivo” que defiende una agenda prominería. En un sentido amplio, este artículo examina, por un lado, la forma en que la contraposición de estas divisiones ecopolíticas se movilizan en Ecuador con el propósito de producir un nuevo nacionalismo; y, por otro, cómo las subjetividades medioambientales existentes en distintos sectores se posicionan frente al estado. El análisis se centra en las representaciones y prácticas que dan forma a las subjetividades medioambientales de actores que, resistiendo la explotación de minas de cobre en sus tierras, operan simultáneamente a escala internacional, nacional y local y, por lo tanto, negocian múltiples –y en ocasiones contradictorios‐ significados respecto a los recursos naturales y su uso.
Grain‐scale pressure variations and chemical equilibrium in high‐grade metamorphic rocks
Authors: Tajčmanová L. , Podladchikov Y. , Powell R. , Moulas E. , Vrijmoed J.C. , Connolly J.A.D. 
Published: December 2013

AbstractIn the classical view of metamorphic microstructures, fast viscous relaxation (and so constant pressure) is assumed, with diffusion being the limiting factor in equilibration. This contribution is focused on the only other possible scenario – fast diffusion and slow viscous relaxation – and brings an alternative interpretation of microstructures typical of high‐grade metamorphic rocks. In contrast to the pressure vessel mechanical model applied to pressure variation associated with coesite inclusions in various host minerals, a multi‐anvil mechanical model is proposed in which strong single crystals and weak grain boundaries can maintain pressure variation at geological time‐scales in a polycrystalline material. In such a mechanical context, exsolution lamellae in feldspar are used to show that feldspar can sustain large differential stresses (>10 kbar) at geological time‐scales. Furthermore, it is argued that the existence of grain‐scale pressure gradients combined with diffusional equilibrium may explain chemical zoning preserved in reaction rims. Assuming zero net flux across the microstructure, an equilibrium thermodynamic method is introduced for inferring pressure variation corresponding to the chemical zoning. This new barometric method is applied to plagioclase rims around kyanite in felsic granulite (Bohemian Massif, Czech Republic), yielding a grain‐scale pressure variation of 8 kbar. In this approach, kinetic factors are not invoked to account for mineral composition zoning preserved in rocks metamorphosed at high grade.
Patient factors associated with incidents of aggression in a general inpatient setting
Authors: Williamson Rosalyn , Lauricella Kate , Browning Alexandra , Tierney Elizabeth , Chen Josephine , Joseph Stephen , Sharrock Julie , Trauer Tom , Hamilton Bridget 
Published: December 2013

Aims and objectivesTo determine patient factors associated with aggressive (code grey) events in the setting of a metropolitan hospital during a six‐month period, to inform screening and prevention practices.BackgroundPatient aggression continues to place nurses and patients at risk. Nurses need to be able to identify situations that are likely to escalate into aggression in order to ensure their own safety and the quality of care they can provide. Research has focussed on emergency departments and psychiatric units. Approaches that are appropriate for these settings may not fit for the general inpatient setting.DesignA structured audit and epidemiological analysis of hospital population, regarding incidence of aggression.MethodsA retrospective audit of code grey event reports and medical records of patients admitted to 16 general medical‐surgical wards, during a six‐month period. All available records of 121 code grey events were audited. Demographic factors for patients with code grey events were compared with factors for 6472 patients admitted. Statistical tests included chi‐squared, bivariate and logistic regression.ResultsDiagnoses associated with increased risk of code grey were the following: delirium (11 times more likely) and dementia (seven times). Patients were more likely to have a code grey event if they were over 65 years of age (more than twice), were male (more than twice), were a recipient of Veterans' Affairs pension (four times), had never been married or had been admitted through the emergency department (almost twice).ConclusionThis study adds to the current knowledge of the distinctive profile of patients in medical‐surgical settings who are associated with aggressive events.Relevance to clinical practiceIt is recommended that nurses increase their focus on assessment of identified risk factors and documentation of behaviours, to help predict aggressive events, and that this focus be supported by hospital safety and care policy.
Diagnostic and prognostic value of circulating microRNAs in patients with acute chest pain
Authors: Devaux Y. , Mueller M. , Haaf P. , Goretti E. , Twerenbold R. , Zangrando J. , Vausort M. , Reichlin T. , Wildi K. , Moehring B. , Wagner D. R. , Mueller C. 
Published: December 2013

AbstractObjectivesTo address the diagnostic value of circulating microRNAs (miRNAs) in patients presenting with acute chest pain.DesignIn a prospective, international, multicentre study, six miRNAs (miR‐133a, miR‐208b, miR‐223, miR‐320a, miR‐451 and miR‐499) were simultaneously measured in a blinded fashion in 1155 unselected patients presenting with acute chest pain to the emergency department. The final diagnosis was adjudicated by two independent cardiologists. The clinical follow‐up period was 2 years.ResultsAcute myocardial infarction (AMI) was the adjudicated final diagnosis in 224 patients (19%). Levels of miR‐208b, miR‐499 and miR‐320a were significantly higher in patients with AMI compared to those with other final diagnoses. MiR‐208b provided the highest diagnostic accuracy for AMI (area under the receiver operating characteristic curve 0.76, 95% confidence interval 0.72–0.80). This diagnostic value was lower than that of the fourth‐generation cardiac troponin T (cTnT; 0.84) or the high‐sensitivity cTnT (hs‐cTnT; 0.94; both P < 0.001 for comparison). None of the six miRNAs provided added diagnostic value when combined with cTnT or hs‐cTnT (ns for the comparison of combinations vs. cTnT or hs‐cTnT alone). During follow‐up, 102 (9%) patients died. Levels of MiR‐208b were higher in patients who died within 30 days, but the prognostic accuracy was low to moderate. None of the miRNAs predicted long‐term mortality.ConclusionThe miRNAs investigated in this study do not seem to provide incremental diagnostic or prognostic value in patients presenting with suspected AMI.
Effect of bovine colostrum intake on growth, reproductive parameters and survival in red kids
Authors: Abdou H. , Marichatou H. , Beckers J.‐F. , Dufrasne I. , Issa M. , Hornick J.‐L. 
Published: December 2013

SummaryThe aim of this study is to evaluate the efficacy of frozen Azawak colostrum supplementation on body weight (BW), average daily gain (ADG), reproductive parameters (mean age at first parturition, fertility, fecundity, prolificacy) and mortality rate among red kids. The study was conducted at the goat farm secondary centre of Maradi in Niger from September 2010 to September 2011. The control animals (n = 20) were left with their mother, while the treatment animals (n = 20) received in addition 50 ml/animal/day of bovine colostrum at birth and 15 ml/animal/day from d2 to d15. Weight was measured weekly from birth to d365. Mortalities were also recorded over the same period. For reproductive parameters, observations began at weaning (d197). Growth rate was higher (p < 0.001) in supplemented animal, and the treatment effects on ADG were observed up to 150 day after the end of supplementation. A similar long‐lasting trend was also observed in relation to the mortality rate (25% for ColG vs. 55% for ConG; p = 0.05). The age at first kidding tended to be lower in the treated group (13.8 ± 0.7 vs. 14.1 ± 0.8 month; p < 0.1). In conclusion, mild bovine colostrum supplementation induces a long‐lasting positive impact on growth rate and to a lower extent on reproduction parameters and survival rate.