bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dietary calcium intake influences the relationship between serum 25-hydroxyvitamin D3 (25OHD) concentration and parathyroid hormone (PTH) concentration
Authors: Patel Prerna , Mughal M Zulf , Patel Pinal , Yagnik Bhrugu , Kajale Neha , Mandlik Rubina , Khadilkar Vaman , Chiplonkar Shashi A , Phanse Supriya , Patwardhan Vivek , Patel Ashish , Khadilkar Anuradha 
Published: September 2015

ObjectivesTo investigate whether dietary calcium intake will modify the relationship between serum 25-hydroxyvitamin D3 (25OHD) with intact serum parathyroid hormone (PTH) concentrations in apparently healthy Indian adolescents.Study designCross-sectional study.Setting and participantsApparently healthy adolescents aged 10–14 years (n=181), from Gujarat, western India. Study conducted from January 2012 to March 2014.MethodsSerum 25OHD concentrations and intact serum PTH concentrations (both using chemiluminescent microparticle immunoassay) were measured. Diet was recorded through 24 h diet recall and calcium intake was computed (C-diet V.2.1). To assess relationship between 25OHD and PTH, data were dichotomised according to median calcium intakes (520 mg/day) and relationship between serum 25OHD and PTH in the two subgroups was plotted.ResultsSubjects with calcium intakes above median (>520 mg/day) had lower intact serum PTH values for given serum 25OHD concentration while those with calcium intakes below median (<520 mg/day) had higher intact serum PTH values for given serum 25OHD concentration. Serum 25OHD concentration was negatively correlated with intact serum PTH concentration at lower as well as higher calcium intakes (r=− 0.606 and −0.483, respectively, p<0.01 for both). Using a regression analysis, predicted values for intact serum PTH concentration for the given serum 25OHD concentrations were plotted. The plot revealed a negative shift with increasing calcium intake.ConclusionsDietary calcium intake modifies the relationship between serum 25OHD concentrations and intact serum PTH concentrations. Thus, dietary calcium intake should be taken into account when assessing an individual's vitamin D status.
Culture-centered approaches: the relevance of assessing emotional health for Latinos with type 2 diabetes
Authors: Concha Jeannie Belinda , Mezuk Briana , Duran Bonnie 
Published: September 2015

ObjectiveWithin Latino culture, there is a belief that strong emotions can cause diabetes. Because of this belief and evidence regarding the bi-directional relationship between depression and diabetes, the objectives of this study were to determine if medical doctors are asking Latinos with diabetes about emotional problems and to assess attitudes toward professional help for emotional problems.Research design and methodsData come from the nationally representative National Latino and Asian American Study and the National Comorbidity Survey Replication study. Only Latino subsamples were included (n=3076). A smaller subsample with complete data (n=2568) was used for the inquiry outcome variable. Weighted χ2analysis and logistic regression were conducted to determine the likelihood of being asked about emotional problems and attitudes toward professional help.ResultsLatinos with mood disorders or anxiety (MD/AX; OR 2.84, 95% CI 2.02 to 4.00), diabetes only (OR 1.69, 95% CI 1.06 to 2.69), and co-occurring diabetes and MD/AX (OR 6.67, 95% CI 2.33 to 19.04) were more likely to be asked about emotional problems, relative to Latinos without diabetes or MD/AX. A minority of respondents with diabetes (32%) were asked about emotional problems. Respondents with diabetes only were more likely to feel comfortable talking to a professional for personal problems compared with those without diabetes or MD/AX (OR 1.44, 95% CI 0.99 to 2.09). Although the relationship between having diabetes and feeling comfortable taking to a professional is not statistically significant, z-test statistics indicate that having diabetes influences attitudes about discussing emotional problems.ConclusionsAmong Latinos, having diabetes is associated with greater likelihood of being asked about emotional problems and feeling comfortable talking to a professional about personal problems. Consistent with the cultural relevance of emotions as a cause of diabetes, asking about emotional problems may be a useful approach for engaging Latinos into a discussion about their diabetes self-care activities.
Implication of the Autologous Immune System in BCR–ABL Transcript Variations in Chronic Myelogenous Leukemia Patients Treated with Imatinib
Authors: Clapp Geoffrey D. , Lepoutre Thomas , El Cheikh Raouf , Bernard Samuel , Ruby Jérémy , Labussière-Wallet Hélène , Nicolini Franck E. , Levy Doron 
Published: September 2015

Abstract
Imatinib and other tyrosine kinase inhibitors (TKI) have improved treatment of chronic myelogenous leukemia (CML); however, most patients are not cured. Deeper mechanistic understanding may improve TKI combination therapies to better control the residual leukemic cell population. In analyzing our patients' data, we found that many patients who otherwise responded well to imatinib therapy still showed variations in their BCR–ABL transcripts. To investigate this phenomenon, we applied a mathematical model that integrates CML and an autologous immune response to the patients' data. We define an immune window or a range of leukemic loads for which the autologous immune system induces an improved response. Our modeling results suggest that, at diagnosis, a patient's leukemic load is able to partially or fully suppress the autologous immune response developed in a majority of patients, toward the CML clone(s). Imatinib therapy drives the leukemic population into the “immune window,” allowing the patient's autologous immune cells to expand and eventually mount an efficient recognition of the residual leukemic burden. This response drives the leukemic load below this immune window, allowing the leukemic population to partially recover until another weaker immune response is initiated. Thus, the autologous immune response may explain the oscillations in BCR–ABL transcripts regularly observed in patients on imatinib. Cancer Res; 75(19); 4053–62. ©2015 AACR.
A Systematic Analysis Reveals Heterogeneous Changes in the Endocytic Activities of Cancer Cells
Authors: Elkin Sarah R. , Bendris Nawal , Reis Carlos R. , Zhou Yunyun , Xie Yang , Huffman Kenneth E. , Minna John D. , Schmid Sandra L. 
Published: September 2015

Abstract
Metastasis is a multistep process requiring cancer cell signaling, invasion, migration, survival, and proliferation. These processes require dynamic modulation of cell surface proteins by endocytosis. Given this functional connection, it has been suggested that endocytosis is dysregulated in cancer. To test this, we developed In-Cell ELISA assays to measure three different endocytic pathways: clathrin-mediated endocytosis, caveolae-mediated endocytosis, and clathrin-independent endocytosis and compared these activities using two different syngeneic models for normal and oncogene-transformed human lung epithelial cells. We found that all endocytic activities were reduced in the transformed versus normal counterparts. However, when we screened 29 independently isolated non–small cell lung cancer (NSCLC) cell lines to determine whether these changes were systematic, we observed significant heterogeneity. Nonetheless, using hierarchical clustering based on their combined endocytic properties, we identified two phenotypically distinct clusters of NSCLCs. One co-clustered with mutations in KRAS, a mesenchymal phenotype, increased invasion through collagen and decreased growth in soft agar, whereas the second was enriched in cells with an epithelial phenotype. Interestingly, the two clusters also differed significantly in clathrin-independent internalization and surface expression of CD44 and CD59. Taken together, our results suggest that endocytotic alterations in cancer cells that affect cell surface expression of critical molecules have a significant influence on cancer-relevant phenotypes, with potential implications for interventions to control cancer by modulating endocytic dynamics. Cancer Res; 75(21); 4640–50. ©2015 AACR.
Contribuição dos estudos de caso e da pesquisa indiciária para a história do espetáculo: o lundu que Maria Baderna teria dançado em Recife
Authors: Rabetti Maria De Lourdes , Alcure Adriana Schneider 
Published: September 2015

<div class="page" title="Page 2"><div class="layoutArea"><div class="column"><p><span>Este texto é focado no lundu dançado no Brasil pela bailarina italiana Maria Baderna. É resultado de um estudo de caso desenvolvido por meio de pesquisa indiciária. Elegeu-se o Lundu d’Amarroá, que Baderna dançou em 1851 no Teatro Santa Isabel de Recife. A pesquisa de indícios se situou no cruzamento de dois eixos fundamentais: a análise de dados encontrados em fontes documentais jornalísticas e a análise de descrições elaboradas por biógrafos, cronistas e estudiosos. A hipótese é a de que o teatro do século XIX no Brasil constitui-se de fortes bases musicais, transborda teatralidade e atrita com barreiras de gênero. O objetivo deste estudo é contribuir para a verificação dos interesses e das possibilidades abertas pelos estudos históricos em teatro, já que certas persistências ou questões significativas engendradas por experiências cênicas passadas podem interessar ao teatro contemporâneo. </span></p></div></div></div>
Behavioural changes in mothers and maternally sensitised female mice
Authors: Szabó Éva R. , Cservenák Melinda , Lutz Thomas A. , Gévai Lőrinc , Endrényi Miklós , Simon László , Dobolyi Árpád 
Published: September 2015

The maternal motivation and depression-like behaviour of primiparous mother and maternally sensitised virgin female mice were investigated. During a 1-h test period, dams and sensitised female mice spent significantly more time in pup-associated than in control cages when they could freely choose between them, while virgin control and ovariectomised females had no such preference. In the forced swim test, the time spent in active (swimming and struggling) and passive (floating) behaviours was measured for 6 min. Mother mice spent more time engaged in active behaviours than virgin and sensitised female mice, while the latter two groups did not differ from each other in the forced swim test. The results suggest that maternal motivation is increased in postpartum mothers and maternally sensitised female mice. We also provide the first demonstration that postpartum mother mice display anti-depression-like behaviours in the forced swim test, while maternally sensitised females do not show such emotional changes.
An aberrant nematode, Baldwinema n. gen. (Nematoda: Panagrolaimomorpha: Panagrolaimidae), from Iran with description of three new species
Authors: Atighi Mohammad Reza , Pourjam Ebrahim , Bert Wim , Pedram Majid , Ghaemi Razieh , Panahandeh Yousef 
Published: September 2015

A new genus of Panagrolaimidae, together with three new species, is proposed based on morphological, morphometric and molecular studies. Baldwinema n. gen. is unique in the Tylenchina by a combination of the following characters: having valvular median bulb, no valve in terminal pharyngeal bulb and absence of stylet. It is further characterised by cylindrical body, thin and finely annulated cuticle, lateral field with two lines (forming a single plain band), fused lips, small longitudinal amphidial openings located on lateral lips, lip region without labial probolae, with six inner and six outer labial and four cephalic papillae (as seen using SEM images), stoma aberrant, cheilostom and gymnostom of equal length, cheilostom with thin wall, gymnostom with clear and thick wall, and stegostom beginning with a tubular thin wall and ending with a thicker wall. Baldwinema ilamense n. gen., n. sp., the type, is characterised by its short post-vulval uterine sac of 7.7 (6.0-9.0) μm long, female tail length of 147 (120-175) μm, shape of gubernaculum, and arrangement of male genital papillae; B. ardabilense n. gen., n. sp. by its short post-vulval uterine sac of 11.5 (9.0-15.0) μm, female tail length of 150 (136-169) μm, shape of gubernaculum, and arrangement of male genital papillae; and B. golestanense n. gen., n. sp. by its long post-vulval uterine sac of 16 (13-21) μm, female tail length of 200 (174-220) μm, shape of gubernaculum, and arrangement of male genital papillae. Phylogenetic analyses based on sequences of the small subunit (SSU) ribosomal RNA gene showed that the new genus is nested within the Panagrolaimidae. However, LSU data did not demonstrate monophyly of the Panagrolaimidae.
Pure or Mixed? The Evolution of Three Grounds of Judicial Review of the Administration in British and Israeli Administrative Law
Authors: Cohn Margit 
Published: September 2015

This article challenges common understandings about the distinct features of the so-called “mixed jurisdictions”. One of the main features found in this group of legal systems, it is argued, is that they are civil-law in nature in the sphere of private law, while their public law sphere is typically Anglo-American. I argue that this may be correct as far as the structural elements of these two branches of law, for example with regard to the court structure; it may also be relevant in the context of the general, overarching values underlying both branches of law. However, as far as the detailed arrangements are concerned, a variety of set-ups reflect different types of mixes and combinations in all legal systems, including “mixed jurisdictions”: innovation, transplantation and adoption of which can be traced inter alia to global crosscutting between these two families of legal systems.This argument is developed through an analysis of the evolution of three grounds of review of the administration-unreasonableness, proportionality and legitimate expectations/ administrative promise-in the United Kingdom, the “ancestor” of the common law family of legal systems, and in Israel, currently considered a mixed jurisdiction. I show that both innovation and reliance on civil law constructs can be found in both systems just as much as common law constructs. The influence of EU law, especially ECtHR jurisprudence, renders the public law of the United Kingdom, to a certain extent, to be more civil-law-like than its so-called daughter system. Whether this mix of patterns is an unavoidable result of the irresolvable tension between exclusionism and openness, both willful and subjected, or matter that is particular to the distinct nature of administrative law and its case-by-case development in common law systems is a matter for further consideration. Clearly, though, legal reality, at least in the field studied in this article, challenges the viability of the distinction between “pure” and “mixed” legal systems.
The Methodology Used to Interpret Customary Land Tenure
Authors: Pienaar Gerrit 
Published: September 2015

Customary land tenure is normally not based on codified or statutory sources, but stems from customary traditions and norms. When westernised courts have to interpret and adjudicate these customary traditions and norms, the normal rules of statutory interpretation cannot be followed. The court has to rely on evidence of the traditional values of land use to determine the rules connected to land tenure.Previously courts in many mixed jurisdictions relied on common or civil law legal principles to determine the nature of customary land tenure and lay down the principles to adjudicate customary land disputes among traditional communities, or between traditional and westernised communities in the same jurisdiction. Many examples of such westernised approach can be found in case law of Canada and South Africa. The interpretation of the nature of customary land tenure according to common law or civil law principles has been increasingly rejected by higher courts in South Africa and Canada, e.g. in Alexkor Ltd v The Richtersveld Community 2004 5 SA 469 (CC) and Delgamuukw v British Columbia 1997 3 SCR 1010.This paper explores the methodology the courts should follow to determine what the distinctive nature of customary land tenure is. As customary land tenure is not codified or based on legislation, the court has to rely, in addition to the evidence of indigenous peoples, on the expert evidence of anthropologists and sociologists in determining the nature of aboriginal title (in Canada) and indigenous land tenure (in South Africa). The court must approach the rules of evidence and interpret the evidence with a consciousness of the special nature of aboriginal claims and the evidentiary difficulties in proving a right which originates in times where there were no written records of the practices, customs and traditions engaged in. The court must not undervalue the evidence presented simply because that evidence does not conform precisely with the evidentiary standards that would be applied in, for example, a private law tort case.
Assessment of acute lung injury/acute respiratory distress syndrome using B-type brain natriuretic peptide
Authors: Sun Yi-zhu , Gao Yan-ling , Yu Qing-xia , Wang Jing , Xia Yong-hon , Lin Hong-yang , Zhou Shao-ling 
Published: September 2015

Objectives To investigate the clinical value of B-type natriuretic peptide (BNP) in the assessment of severity and prognosis in acute lung injury/acute respiratory distress syndrome (ALI/ARDS). Methods Plasma BNP level, arterial blood gases, serum C-reactive protein level, alveolar–arterial oxygen tension difference and oxygenation index were measured in patients with and without ALI/ARDS within 24 h of admission to an intensive care unit. Patients with ALI/ARDS were divided into mild, moderate or severe groups according to the degree of hypoxaemia. Survival >28 days was recorded. Results A total of 59 patients with ALI/ARDS and 14 patients without ALI/ARDS were included in the study. Of the patients with ALI/ARDS, 18 had mild hypoxaemia, 20 had moderate hypoxaemia and 21 had severe hypoxaemia. The mean ± SD BNP level was significantly higher in all three ALI/ARDS groups (92.41 ± 28.19 pg/ml, 170.64 ± 57.34 pg/ml and 239.06 ± 59.62 pg/ml, respectively, in the mild, moderate and severe groups) than in the non-ALI/ARDS group (47.27 ± 19.63 pg/ml); the increase in BNP level with increasing severity was also statistically significant. When divided according to outcome, the BNP level in the death group (267.07 ± 45.06 pg/ml) was significantly higher than in the survival group (128.99 ± 45.42 pg/ml). Conclusions The BNP level may be of value in evaluating severity and prognosis in patients with ALI/ARDS.
Lectura Dantis: Purgatorio XXVI
Authors: Ellerbrock Karl Philipp 
Published: September 2015

Riassunto
Nel canto XXVI del Purgatorio, noto per l’omaggio alla memoria di due grandi poeti in volgare, Dante problematizza il rapporto tra fama letteraria e salvezza dell’anima. Sorprendentemente il canto dello stilnovista Guido Guinizzelli e del trovatore Arnaut Daniel è penetrato da una retorica dell’anonimità: le anime qui presenti, invece di figurare nominatamente, sembrano scomparire nel processo collettivo della purificazione. Il contrappasso riservato ai poeti riguarda il loro uso metaforico - »lussurioso« - d’immagini religiose, come il biblico ardere, da loro impiegato per parlare poeticamente della passione amorosa, anzi della poesia stessa. Per poter raggiungere il paradiso, i poeti sono condannati a rinunciare al loro uso individuale ed eretico della parola, diventando quindi stilisticamente indiscernibili. Così il ›Guido‹ immaginato da Dante è una versione ridotta dell’autore di »Al cor gentil«, mentre ›Arnaut‹ non è più riconoscibile come un rappresentante del trobar clus. L’incontro tra ›Dante‹, ›Guido‹ ed ›Arnaut‹ prende la forma di una conversazione velata, quasi tacita, nella quale tuttavia i poeti dispiegano una retorica ancor più raffinata per affermare il valore della poesia, che sta per spegnersi nelle fiamme del purgatorio.
Untangling the Relationship between Human Resource Management and Corporate Entrepreneurship: The Mediating Effect of Middle Managers’ Knowledge Sharing
Authors: Mustafa Michael , Lundmark Erik , Ramos Hazel Melanie 
Published: September 2015

Abstract
Although there is a growing body of literature linking human resource management (HRM) and corporate entrepreneurship (CE), there is still insufficient understanding of the mechanisms underlying this relationship. This paper focuses on middle managers’ knowledge-sharing behavior as an important mediator in the HRM–CE relationship. We test our hypotheses using data collected from 163 Malaysian middle managers. The paper finds that about a third of the relationship between High-Performance Human Resource Practices and CE can be accounted for by middle managers’ knowledge-sharing behavior. The findings provide quantitative empirical support for theoretical claims of the importance of middle managers’ knowledge sharing in fostering CE, and for the importance of HRM in fostering such knowledge sharing. The study contributes to the literature on the HRM–CE relationship by disentangling the underlying mechanisms and by providing empirical support for this relationship in a Malaysian context.
LTCC Phase Shifters Based on Tunable Ferroelectric Composite Thick Films
Authors: Nikfalazar M. , Kohler C. , Heunisch A. , Wiens A. , Zheng Y. , Schulz B. , Mikolajek M. , Sohrabi M. , Rabe T. , Binder J. R. , Jakoby R. 
Published: September 2015

AbstractThis paper presents, the investigation of tunable components based on LTCC technology, implementing ferroelectric tunable thick-film dielectric. The tunable loaded line phase shifters are fabricated with metal-insulator-metal (MIM) varactors to demonstrate the capabilities of this method for packaging of the tunable components. The MIM varactors consist of one tunable dielectric paste layer that is printed between two silver layers. The tunable ferroelectric paste is optimized for LTCC sintering temperature around 850°C. The phase shifters are fabricated in two different process. They were achieved a figure of merit of 24°/dB (phase shift 192°) at 3 GHz and 18°/dB (phase shift 98°) at 4.4 GHz by using seven unit cells that each unit cell consisting of two MIM varactors.