bluuebunny/crossref_metadata_2025_split huggingface dataset:
Quality of life of breast cancer patients in Amhara region, Ethiopia: A cross-sectional study
Authors: Alem Tamrat , Nigatu Dabere , Birara Amsalu , Fetene Tamene , Giza Mastewal 
Published: June 2024

Background
Although breast cancer has a markedly higher incidence in developed countries, seven out of ten deaths occur in developing countries, including Ethiopia. However, there is a limited information on the quality of life (QoL) among breast cancer patients in Ethiopia, notably in the Amhara region. Therefore, this study aimed to assess the QoL and its associated factors among patients with breast cancer in the Amhara Region, Ethiopia.

Methods
An institutional based cross-sectional study was conducted from 25th March 2019 to 7th July 2019. A systematically selected sample of 256 breast cancer patients were participated in the study. A standardized interviewer-administered Amharic version questionnaire was used to collect the data. We used the European Organization for Research and Treatment of Cancer quality of life questionnaire core 30 (EORTC QLQ C30) and breast cancer supplementary measure (QLQ-BR23) to measure QoL. The data were analyzed by SPSS version 23. A binary logistic regression model was fitted to identify the predictors of QoL. The adjusted odds ratio (AOR) with a 95% confidence interval (CI) was reported to show the strength of the association.

Results
Sixty-eight percent of breast cancer patients had poor QoL (68.4%; 95% CI: 62.5–73.8). The mean score of QoL was 70.6 (standard deviation (SD) ±13.9; 95% CI: 69.0–72.4). All functional component scores were less than 75 on the symptom scale. Diarrhea (11.6), constipation (17.5), and dyspnea (24.7) were less noticeable symptoms. Being out of marriage (AOR = 2.59, 95% CI: 1.32–5.07), being poor (AOR = 2.39, 95%CI: 1.32–5.03), being non-housewife (AOR = 3.25, 95% CI: 1.16–7.22), and being complaints of dyspnea (AOR = 3.48, 95% CI: 1.79–6.79), and insomnia (AOR = 2.03, 95% CI: 1.05–3.91) were significantly associated with QoL.

Conclusions
The proportion of poor QoL among breast cancer patients was high. Health care professionals should give attention to breast cancer patients who are out of marriage, poor and non-housewife while offering the recommended treatment courses.
Suboptimal factors in maternal and newborn care for refugees: Lessons learned from perinatal audits in the Netherlands
Authors: Verschuuren A. E. H. , Tankink J. B. , Postma I. R. , Bergman K. A. , Goodarzi B. , Feijen-de Jong E. I. , Erwich J. J. H. M. 
Published: June 2024

IntroductionRefugees and their healthcare providers face numerous challenges in receiving and providing maternal and newborn care. Research exploring how these challenges are related to adverse perinatal and maternal outcomes is scarce. Therefore, this study aims to identify suboptimal factors in maternal and newborn care for asylum-seeking and refugee women and assess to what extent these factors may contribute to adverse pregnancy outcomes in the Netherlands.MethodsWe conducted a retrospective analysis of national perinatal audit data from 2017 to 2019. Our analysis encompassed cases with adverse perinatal and maternal outcomes in women with a refugee background (n = 53). Suboptimal factors in care were identified and categorized according to Binder et al.’s Three Delays Model, and the extent to which they contributed to the adverse outcome was evaluated.ResultsWe identified 29 suboptimal factors, of which seven were related to care-seeking, six to the accessibility of services, and 16 to the quality of care. All 53 cases contained suboptimal factors, and in 67.9% of cases, at least one of these factors most likely or probably contributed to the adverse perinatal or maternal outcome.ConclusionThe number of suboptimal factors identified in this study and the extent to which they contributed to adverse perinatal and maternal outcomes among refugee women is alarming. The wide range of suboptimal factors identified provides considerable scope for improvement of maternal and newborn care for refugee populations. These findings also highlight the importance of including refugee women in perinatal audits as it is essential for healthcare providers to better understand the factors associated with adverse outcomes to improve the quality of care. Adjustments to improve care for refugees could include culturally sensitive education for healthcare providers, increased workforce diversity, minimizing the relocation of asylum seekers, and permanent reimbursement of professional interpreter costs.
Atrial Fibrillation Following Esophageal Stent Placement: A Rare but Important Complication to Recognize
Authors: Mirminachi Seyedbabak , Yaghnam Ibrahim , Muallem Samer , Razjouyan Hadie 
Published: June 2024

ABSTRACT
There is a risk of new-onset atrial fibrillation (AF) in patients with esophageal cancer treated with neoadjuvant chemotherapy/radiotherapy followed by esophagectomy. However, the occurrence of AF after stent placement for esophageal cancer is less explored. Here, we present a case of esophageal cancer where AF developed poststent placement. The potential mechanisms linking stent placement and atrial dysrhythmias may involve left atrial compression and epicardial irritation. It is essential to remain vigilant about this arrhythmia following stent placement to promptly identify any early signs of atrial dysrhythmias, particularly given the frequently observed hypercoagulable state in these individuals.
Decreased Serum Tryptophan and Severe Ulcerative Damage of Colon Mucosa Identify Inflammatory Bowel Disease Patients With High Risk of Cytomegalovirus Colitis
Authors: Rüsing Sophia , Welz Lina , Pfitzer Constanze , Harris Danielle Monica , Röcken Christoph , Rosenstiel Philip , Nikolaus Susanna , Tran Florian , Schreiber Stefan , Aden Konrad , Sievers Laura Katharina 
Published: June 2024

INTRODUCTION:
Patients with inflammatory bowel disease (IBD) are predisposed to the reactivation of viral infections such as cytomegalovirus (CMV). Clinical discrimination of disease flares and colonic CMV reactivation is difficult in patients with established diagnosis of IBD, and there are no reliable noninvasive diagnostic tools yet. Furthermore, the influence of novel therapeutics including biologicals and Janus kinase inhibitors on the risk of CMV colitis is unclear. The goal of this study was to identify risk factors and clinical determinants of CMV colitis that could serve as minimally invasive markers both for active CMV colitis and relapse.

METHODS:
To this end, a retrospective analysis of 376 patients with suspected or confirmed CMV colitis 2016–2023 was performed.

RESULTS:
Previous administration of systemic steroids increased the odds of CMV colitis to OR 4.6. Biologicals did not change the incidence of CMV colitis but decreased the OR of a relapse to 0.13. Clinical parameters such as severely bloody diarrhea, intense microscopic ulcerative damage, and decreased serum tryptophan correlated with detection of CMV. Importantly, persistent decrease of tryptophan was observed in patients with CMV relapse. Furthermore, tryptophan degradation through the kynurenine pathway was increased in CMV-positive patients.

DISCUSSION:
Taken together, we identify decreased serum tryptophan as a novel potential minimally invasive marker to aid identification of IBD patients with active CMV colitis and at high risk for relapse.
Neuere Entwicklungen in der örtlichen und regionalen Energieversorgungsplanung
Authors: Lutter Horst 
Published: June 2024

Eine stringentere Anpassung der Energieversorgungsplanung an die vorhandene Siedlungsstruktur und die Siedlungsentwicklung hilft die energiepolitischen Ziele der Regierungen von Bund und Ländern umzusetzen. Insbesondere in der Wärmeversorgung können durch siedlungsangepaßte Konzepte erhebliche Potentiale der Energieeinsparung Ölsubstitution und Umweltentlastung ausgeschöpft werden.Das interministrielle Arbeitsprogramm „Örtliche und regionale Energieversorgungskonzepte“ des Bundesministers für Forschung und Technologie und des Bundesministers für Raumordnung Bauwesen und Städtebau soll die Möglichkeiten und Auswirkungen von siedlungsangepaßten, integrierten Energieversorgungskonzepten an konkreten Modellstädten und -regionen erforschen. In diesem Beitrag werden die ersten Erfahrungen der 25 Modellkonzepte des Arbeitsprogramms ergebnisorientiert ausgewertet. Mit einer groben siedlungsstrukturellen Typisierung in Verdichtungsräume und Großstädte, Klein- und Mittelstädte sowie den ländlichen Raum wird versucht, die verschiedenen Konzeptbausteine einer siedlungsstrukturellen Bewertung zu unterziehen. Neben Maßnahmen zur Energieeinsparung im Gebäudebestand und bei der Neubauplanung werden dabei die Ausbaustrategien der leitungsgebundenen Energieversorgungssysteme (Fern- und Nahwärme, Gas) sowie der Einsatz von konventionellen Energieträgern behandelt.Schließlich sind für die drei Siedlungstypen drei – bereits abgeschlossene – Modellstudien im Überblick dargestellt.
Exploring Harmful Illocutionary Forces Expressed by Older Adults with and Without Alzheimer’s Disease: A Multimodal Perspective
Authors: Dai Congchen , Huang Lihe 
Published: June 2024

Abstract
This study examines the multimodal pragmatic abilities of older adults experiencing typical aging in contrast to those with Alzheimer’s disease, via the statistical and comparative analysis of harmful illocutionary forces expressed in their discourse. The results indicated that individuals with Alzheimer’s disease showed a noticeable lack of emotional engagement, which hindered the felicity of illocutionary forces. Furthermore, these patients struggled to use appropriate prosodic indicators, alongside a diminished integration of conventional gestures. Highlighting the significance of multimodal illocutionary force indicators in speech acts, this study contributes to a more intricate comprehension of interpersonal communication.
Evaluation of the effluent concentrations of Karbala wastewater treatment plant using reliability analysis
Authors: Atea Ruqayah Fadhil , Al-Saadi Riyadh Jasim Mohammed , Al-Baidhani Jabbar H. , Hassan Waqed H. 
Published: June 2024

Abstract
The effective and consistent operation of wastewater treatment plant systems (WWTPs) is crucial for the sustainability of the environment and public health protection. The main objective of the present study is concentrated on assessing the reliability of the Karbala wastewater treatment plant’s (WWTP’s) performance. It investigates the plant’s efficiency through the weekly concentration values of three key water quality indicators, which are biochemical oxygen demand (BOD), total suspended solids (TSS), and chemical oxygen demand (COD) collected over 4 years of operation from 2020 to 2023. The methods employed were the coefficient of reliability (COR) method for plant performance in removing the effluent concentrations of 5-day biochemical oxygen demand, COD, and TSS. The analysis found that the COR values were generally close to 1 for all years, with the lowest value recorded at 0.71 in 2020, during the initial stabilization phase of the WWTP. The main finding was that the Karbala WWTP has been effective in pollutant removal. The present study is important because it supplies dependable data that wastewater treatment operators can use to assess their daily operations and gauge the success of biological treatment methods. It is worth noting that no study has been done on the reliability model for examining the quality of wastewater of the Karbala WWTP, and such a method of analysis is considered a new improvement for the evaluation of the plant to meet the Iraqi standards.
Prospects of nanotechnology advances in food adulterant detection, spoilage detection, packaging and preservation applications
Authors: Janakiraman Kumar , Ramesh Abilesh , Sethuraman Vaidevi , Shanmugasundaram Prema Suriyaraj 
Published: June 2024

Abstract
Food is essential for the development and essential functions of our lives. Our typical dietary intake consists of vegetables, fruits, legumes, pulses, grains, and other similar foods. These ingredients can be consumed in their raw form or transformed into delicious recipes. Food adulteration refers to the deliberate introduction of potentially hazardous substances into food or food products to contaminate or adulterate them. Prolonged storage of food without sufficient preservation leads to spoilage, which poses a health risk. Food undergoes degradation over an extended duration of storage, leading to the proliferation of germs on its surface. Nanotechnology revolutionizes food safety by employing precise detection and preservation methods. Nanoparticles play a crucial role in expediting the detection of adulterants, enabling the identification of even minute amounts of contaminants like pesticides or hazardous compounds. This, in turn, ensures the preservation of the quality and safety of food items. Nanosensors are used to identify spoilage by monitoring microbial activity or changes in pH levels, to prevent the intake of spoiled food. Nano-emulsions and coatings can extend the shelf life of products by establishing protective barriers that hinder the ingress of oxygen, moisture, and microbial growth. This process effectively preserves the freshness and nutritional value of the products. In this review, we have discussed the role of nanotechnology in detecting food adulteration, food spoilage, food preservation and food packaging techniques.
TWO MILLENNIA OF CLIMATE HISTORY FOR THE RUSSIAN ALTAI: INTEGRATED RECONSTRUCTION FROM LAKE SEDIMENT DATA
Authors: БАБИЧ В.В. , ДАРЬИН А.В. , РУДАЯ Н.А. , МАРКОВИЧ Т.И. 
Published: June 2024

На основе климатических палеореконструкций, полученных по результатам изучения донных осадков четырех озер Горного Алтая (Телецкое, Кучерлинское, Нижнее Мультинское и Среднее Мультинское), впервые построена обобщенная палеохронология годовых температур для территории Российского Алтая на непрерывной временной шкале за последние два тысячелетия. Полученная интегрированная температурная реконструкция отображает все известные для данного временного интервала климатические события: теплый Романский период (~ от 200 до 500 г. н. э.), холодный период Темного века (~ от 500 до 750 г. н. э.), Средневековая теплая климатическая аномалия (~ от 750 до 1300 г. н. э.) и последующий Малый ледниковый период (~ от 1300 до 1850 г. н. э.). Сопоставление обобщенной климатической хронологии с результатами температурных палеореконструкций по другим климатическим индикаторам для Российского Алтая, а также прилегающих к нему территорий Западной Сибири, Тывы и Западной Монголии показало полную синхронность в выделении указанных климатических событий и их временных границ. Данный факт позволяет считать, что построенная обобщенная температурная реконструкция отображает единый ход климатического развития в пределах значительной части Центрально-Азиатского региона за последние 2000 лет. Сравнительный анализ обобщенной климатической реконструкции с имеющимися количественными реконструкциями для различных регионов Северного полушария, а также с усредненной температурной хронологией для Северного полушария в целом также демонстрирует высокое сходство в проявлении и синхронности основных климатических событий, что свидетельствует о том, что климат Центральной Азии на протяжении последних двух тысячелетий менялся в полном соответствии с общим глобальным климатическим сценарием.
A continuous history of annual air temperatures in the Russian Altai for the past 2000 years has been reconstructed for the first time by integrating climate archives stored in the bottom sediments of four lakes in Gorny Altai (Teletskoye, Kucherla, Lower Multa, and Middle Multa). The integrated chronology comprises all known climate events of the two millennia time span: Roman warm epoch (~200 to 500 AD), Dark Age cold epoch (~500 to 750 AD), medieval warming (~750 to 1300 AD), and Little Ice Age (~1300 to 1850 AD). The events distinguished in the integrated climate reconstruction agree perfectly in number and time with the events reconstructed from other climate proxies for the Altai and adjacent areas of West Siberia, Tyva, and West Mongolia. Therefore, the temperature patterns represent a common course of the 2000-year climate evolution over a large part of Central Asia. Similar synchronicity is observed with the available quantitative climate reconstructions for the Northern Hemisphere and its different regions. It means that the climate change in Central Asia over the past two millennia has followed the general global scenario.
Changes in the Fatty Acid Composition of Corn Seedlings under the Influence of the Microbiological Complex
Authors: Melnychuk T.M. , Midyk S.V. , Biliavska L.O. , Makarchuk O.S. , Zhemoida V.L. , Vishovan Yu.Yu. , Loboda M.I. , Skrotsky S.O. , Samkova O.P. , Korniyenko V.I. , Spriazhka R.O. 
Published: June 2024

Orientation of agricultural production to ecological expediency leads to interest in the use of microbial preparations that are able to increase the resistance of plants to negative environmental factors and activate germination processes. This study was conducted with the aim to investigate the influence of a microbiological complex on the sowing properties of seeds and the fatty acid composition of seedlings of different breeding samples of corn. Methods. Corn seeds of two lines 1-Ak026 and 2-Ak033 and their simple interline hybrid, which is the parent component of the three-line hybrid NUBiSe included in the State Register of plant varieties suitable for distribution in Ukraine, were used for the research. Seed inoculation was carried out with a microbial complex, which contained biological preparations Sporazyn, Avercom, and Phytovit. Seedlings from the seeds of the corresponding corn samples not treated with the microbial complex served as controls. The fatty acid composition of lipids was determined in the biological material of corn seedlings of different variants of the experiment. The Folch method was used to extract fats from plant material. Hydrolysis and methylation of fatty acids of lipids obtained from corn seedlings was carried out according to DSTU ISO 5509-2002. Fatty acids were detected and identified by gas chromatography. The quantity of fatty acids was calculated by the method of internal normalization in percentages. Results. The influence of the microbiological complex on the quantitative and qualitative composition of fatty acids of the lipid complex of corn seedlings was established, which depended on the breeding sample. In the process of research, 22 fatty acids were detected and quantitatively identified in corn seedlings. In the seedlings of lines 1-Ak033 and 2-Ak033, 20 and 19 of them were found, respectively, and in the hybrid – 18. The highest percentage content (more than 90 %) was revealed for palmitic (C16:0), oleic (C18:1n9c), and linoleic (C18:2ω6c) fatty acids. The use of the microbial complex made it possible to detect the fatty acids in line 1 and the hybrid that were not detected in the samples without inoculation. Conclusions. The study of the fatty acid composition of the microbial preparation Sporazyn revealed the highest content of unsaturated fatty acids (67.47 %) and the ratio of saturated to unsaturated (0.48). The use of microbiological preparations on corn seeds increased the activity of the germination processes, which led to the improvement of sowing properties and changes in the fatty acid composition of the lipid complex of seedlings of various breeding forms of Zea mays.
Філософія розуму Іммануїла Канта і виклики сучасного суспільства: до 300-річчя з дня народження мислителя
Authors: Єрмоленко Анатолій Миколайович 
Published: June 2024

Творча спадщина Іммануїла Канта, до якої належать теоретична та практична філософія, а також філософська антропологія, має в наш час непересічне філософське та соціально-політичне значення. Наголошено, що в Україні, зокрема в Інституті філософії імені Г.С. Сковороди НАН України, склалася потужна історико-філософська традиція досліджень німецької класичної філософії, фундаментом якої є філософія І. Канта. Кантова практична філософія стала важливим чинником провідних тенденцій сучасної філософії у світі: філософії комунікації та етики дискурсу. Актуальність практичної філософії Канта особливо проявляється сьогодні, в умовах сучасної технологічної цивілізації, кризи та війни, адже його концепт примату практичного (морально-етичного) розуму над теоретичним, технічним та інструментальним розумом відкриває шляхи для розв’язання глобальних проблем сучасності. Ювілей Канта набуває особливої значущості з огляду на російську агресію проти України. Спотворюючи просвітницьке, морально-етичне та універсалістичне спрямування його філософії, російська пропаганда намагається використати її з ідеологічно-пропагандистською метою. Саме тому заходи, присвячені ювілею Канта, є важливим складником боротьби проти російського агресора.
Aubergine Gratin
Authors: D'Aulnay Nathan 
Published: June 2024

Nathan d'Aulnay, the painter, here leaves his studio to claim our attention for the parallel artistry which he exercises in the kitchen. Erudite in the classical cuisine of France, passionately interested in the technical and practical details of culinary operations, he communicates his knowledge with panache and precision. There are few dishes which he enjoys making more than a gratin such as the one which he has chosen to present below.
The Technology of Cooking in the British Isles, 1600 to 1950 - Part I
Authors: Cookson Caroline 
Published: June 2024

Caroline Cookson is engaged in writing a history of housework in the British Isles from about 1700 until the middle of this century. The evolution of cooking techniques is, obviously, an important part of the study. This essay, of which the first part only is printed here, represents 'work in progress', which will need amplification and correction. Comments from readers will be warmly appreciated, especially if they help to resolve any of the problems listed at the end.
Tabbouleh! Tabbouleh! Tabbouleh!
Authors: Roden Claudia 
Published: June 2024

Claudia Roden is well known for her classic book Middle Eastern Food (Nelson 1968, Penguins 1970 and Knopf 1972), a work which combines scholarship with practicality. She has also written a book Oil Coffee (Faber 1977) and is now completing a book on outdoor cookery, and starting one on Jewish food (cf. PPC 1, p. 72). She was born in Cairo and lives ill London.
This contribution concerns the iconic dish Tabbouleh.
Eating Out in Provincial France 1965-1977
Authors: David Elizabeth 
Published: June 2024

The article was originally intended to appear in the 1977 re-issue of the Michael Joseph Ltd. reissue of the hardback edition of French Provincial Cooking but due to space restraints, it was omitted. It was published for the first time in this issue of PPC.
The article concerns eating out in France in the 1960s and 1970s, an era of declining standards according to the author,