bluuebunny/crossref_metadata_2025_split huggingface dataset:
Symptoms of anxiety and depression among osteoporotic women
Authors: Feki A. , Sellami I. , Trabelsi B. , Gassara Z. , Ben Djemaa S. , Abbes A. , Ezzeddine M. , Kallel M. H. , Fourati H. , Akrout R. , Mejdoub Y. , Baklouti S. 
Published: August 2024

IntroductionOsteoporosis (OP) prevalence is on the rise as a result of an ageing population and lifestyle factors such as inactivity. Previous research has reported OP in individuals with depressive symptoms. Furthermore, OP has been shown to be a risk factor for anxiety.ObjectivesIn this study, we aimed to describe anxiety and depression symptoms among osteoporotic women in a university hospital in Tunisia.MethodsA cross-sectional study was conducted between January and June 2023 in a university hospital in Tunisia. Women with postmenopausal OP in the rheumatology department were interviewed. A hospital anxiety and depressive scale was used to describe anxiety and depression symptoms among patients. It consists of seven items for depression (HADS-D) and seven items for anxiety (HADS-A). For each component a score ≤ 7 indicated the absence of symptomatology.ResultsSeventy-two women diagnosed with post-menopausal OP participated in the study. The mean age was 72.5 (±1.08). The median duration of menopause was 23 years (IIQ= [10.5-28.5]). All patients were receiving bisphosphonates. Fifty-eight women (80.5%) were identified with depressive symptoms. The median depression score was 17.5 (IIQ= [9-19]). Physical activity was significantly and inversely associated with the presence of depressive symptoms (r= -6.36; p=10-3). Those who were overweight or even obese had significantly more depressive symptoms than those who were not overweight (94%, 57%, p= 0.001).The median score of anxiety was 16 (IIQ= [9-17]). Sixty-three patients (87.5%) were identified with anxiety symptoms. Physical activity was significantly and inversely associated with the presence of anxiety symptoms (r= -4.89; p=10-3). Women who had bone fractures were significantly more anxious than those without a history of bone fractures (100%, 63%, p<10-3). Patients who were overweight were significantly more anxious than those with normal weight (96%, 57%, p<10-3).ConclusionsPhysical activity and obesity were associated with depression and anxiety among osteoporotic patients. These data are consistent with previous findings That’s why, promoting physical activity and weight loss is essential to preventing mental disorders among osteoporotic women.Disclosure of InterestNone Declared
Spiritual awakening. Substance abuse, dual pathology
Authors: Gordillo Montaño M. J. , Rodriguez Rodriguez L. , Pérez Aparicio C. , Boned Torres S. V. 
Published: August 2024

IntroductionKambó is considered an “ancestral medicine” by the indigenous tribes of the western region of the Amazon.ObjectivesThrough this clinical case, the aim is to present the particularities of the symptoms and management of patients with consumption of not so common substances, such as Kambo or salvia divinorum, as well as the evolution that will occur in a patient with a previous diagnosis of a Depressive Episode.MethodsWe present the case of a 23-year-old male, Gestalt therapy student. History of tobacco, THC, and recent use of salvia divinorum and Kambo. He began follow-up by psychiatry in a private setting three years ago due to a severe depressive episode, having required treatment with antidepressants, antipsychotics and benzodiazepines, and having been triggered by a serious assault. The episode is resolved and follow-up is discontinued. Family history of depressive syndrome and suicide.He resumed contact through the Emergency Department, requiring hospital admission due to symptoms compatible with a manic episode with psychotic symptoms. It begins with behavioral alterations and global insomnia that are related to the consumption of some substance, initially unknown to them, making the skin lesions they presented suspect the consumption of kambo.ResultsWe assess the risk of consuming these substances, which are sometimes used as alternative therapies, and especially in this type of patient, who is more vulnerable and perhaps seeks a way out of the problems they present.ConclusionsIn our case, it triggered a manic episode with psychotic symptoms, which consisted of delusional ideation of mystical content accompanied by auditory hallucinations. The episode took about a month to subside, despite treatment. Subsequently, there have been more episodes with similar characteristics, and they have not been associated with the consumption of kambó, but have been linked to the consumption of “natural medicinal substances.”Disclosure of InterestNone Declared
Enhancing Physical Health in Patients with Severe Mental Disorder: Addressing Physical Multimorbidity
Authors: Filipčić I. Š. , Filipčić I. 
Published: August 2024

IntroductionOver the last two decades, a growing volume of research has discovered a correlation between severe mental disorders (SMD) and early mortality. This is attributed to the elevated incidence of chronic physical illnesses s and multimorbidity, resulting in a reduction of life expectancy by 10-20 years. Individuals with SMD exhibit lower rates of prevention, diagnosis, and treatment for medical comorbidities when contrasted with the general population (GP).ObjectivesThe objective is to assess the prevalence of CPM and its impact on psychiatric treatment outcomes in individuals with SMD, and to propose preventive interventions to enhance physical health.MethodsThis nested cross-sectional study enrolled 343 SSD patients and 620 GEP.ResultsIndividuals diagnosed with SMD encounter CPM earlier in life compared to the GP. Notably, individuals under 35 years old within the schizophrenia spectrum disorder have almost three times higher odds for experiencing CPM compared to their GP counterparts, a difference that is both clinically and theoretically significant. This disparity is especially pronounced among younger women, with the gap widening the younger the patient is in comparison to peers in the general population. CPM has been identified as a factor affecting the outcomes of psychiatric treatment.ConclusionsThe treatment approach for SMD should be tailored to accommodate the diverse physical multimorbidity patterns of patients. It’s imperative for future research to delve into how CPM impacts the outcomes of SMD treatments. There’s a pressing need for detailed treatment guidelines addressing CPM in patients with SMD.Disclosure of InterestNone Declared
Psychosocial interventions for cardiac surgery patients: context of interdisciplinary interaction
Authors: Nikolaeva O. , Babokin V. , Trofimov N. , Alhasan M. 
Published: August 2024

IntroductionMulti-staged and personalized in nature, psychosocial interventions for cardiac surgery patients explain the necessity of relying on the potential of interdisciplinary interactionObjectivesTo present the review of the model of interdisciplinary interaction of experts and institutions in the course of psychosocial interventions for cardiac surgery patients, which is currently used in the Chuvash Republic.MethodsThis model involves the experts and institutions of the regional healthcare system, the regional system of social care, the regional and federal system of education, non-governmental medical and health resort institutions, and private practitioners.ResultsIn the center of this model is the Regional Cardiology Center, which interacts with the Psychotherapeutic Center and the Republican Mental Hospital’s Helpline. It also involves the town hospitals and the central district hospitals, non-governmental clinics and private practitioners. The process of rehabilitation and follow-up care continues in the regional health resorts. The social service centers provide additional support. The institute of chief experts of the regional Health Care Ministry, which includes a psychiatrist, cardiologist, psychotherapist, and psychologist, oversees the overall activity. The clinic faculty professors and associate professors are involved in the development of the programs.ConclusionsThe practical results of using the regional model of interdisciplinary interaction enhance the potential of psychosocial interventions for cardiac surgery patients.Disclosure of InterestNone Declared
Neuropsychiatric Manifestations of Tuberous Sclerosis in a young adult male in a Psychiatry Hospital in Botswana: a case report
Authors: Chabalala W. T. , Bojosi K. , Maphane T. , Olashore A. 
Published: August 2024

IntroductionTuberous sclerosis complex (TSC) is a disorder that affects multiple systems and was first described in 1880. Its symptoms include seizures, intellectual disability, and adenoma sebaceum. TSC is caused by mutations in the TSC1 and TSC2 genes and is inherited in an autosomal dominant manner.ObjectivesThis report highlights a case of a patient with an unusual psychological presentation evaluated in a psychiatric hospital.MethodsThe patient presented with psychotic features and abnormal behavior. A physical examination showed neurocutaneous lesions. After assessment a diagnosis of Tuberous sclerosis complex was confirmed through MRI Brain and genetic testing. Some of his relatives also showed similar neuropsychiatric symptoms.ResultsTuberous sclerosis complex is diagnosed based on TSC Clinical Consensus Group guidelines of 2012. Our patient fulfilled 4 of the major criteria and genetic testing also yielded a pathogenic variant. A TAND checklist (TSC-Associated Neuropsychiatric Disorders) is used to guide clinicians on areas to prioritize when managing TSC patients.Image:Image 2:Image 3:ConclusionsGiven that psychiatry may be the first contact for TSC patients, especially in low-resource settings. Patients referred to psychiatry, therefore, need to be thoroughly examined to exclude neuropsychiatric disorders, and a multidisciplinary team approach is vital in investigating and managing these cases.Disclosure of InterestNone Declared
Introduction and overview of offenders with intellectual disabilities
Authors: Goethals K. 
Published: August 2024

AbstractIntellectual disability (according to the DSM-5) or intellectual developmental disorder (according to the ICD-11) is a disorder with onset during the developmental period that includes both intellectual and adaptive functioning deficits in conceptual, social and practical domains. The term learning disability (LD) is also used, although this term shows more specifically deficits in the domain of learning. The term learning difficulties is often used for specific or generalized intellectual impairment that does not meet all of the criteria of LD.The prevalence of learning disability in prisoners is about 10%. Up to 60% of male prisoners have learning difficulties. Prevalence rates for offending behaviour in patients with LD is higher than in the general population and show a large range, from 2-40%.The main explanatory factor underlying the link between intelligence and offending is the lack of ability to manipulate abstract concepts. Poor academic performance, common in persons with LD, is also linked to offending.With regard to sexual offending, some persons with LD may not have learnt the rules that define acceptable and unacceptable behaviour. Sexual offences may amount to inappropriate, impulsive expressions of emotion rather than premediated violent acts. Violent behaviour in the LD population may be due to frustration, impulsivity or poor problem solving skills. There is no significant difference in the frequency of violent or property offences between individuals with LD and those without. However, sex offences and fire-setting are frequently seen in individuals with LD.Persons with LD are vulnerable suspects and may also be disadvantaged by the criminal justice system because of a lack of appropriate support and legal representation from early stages in the process.In this introductory paper these themes will be addressed.Disclosure of InterestNone Declared
Post-traumatic stress disorder in adolescents during the Covid-19 pandemic: a cross-sectional study of 326 cases
Authors: Mayssa K. , Jaweher B. , Ali K. , Donia B. T. , Imen H. , Hela A. , Khaoula K. , Yousr M. 
Published: August 2024

IntroductionSince December 2019, the coronavirus pandemic has led to the deaths of almost 4.37 million people worldwide and 21,905 people in Tunisia. Containment measures, stress due to fear of infection by the virus and death are likely to be traumatic events, particularly in adolescents, and may lead to the development of symptoms of post-traumatic stress disorder (PTSD).ObjectivesTo determine the prevalence of PTSD in a population of adolescents during the COVID-19 pandemic and to identify the factors associated with it.MethodsThis study was a cross-sectional among a representative sample of students enrolled in secondary schools, in the region of Hamma- Gabes. We used a pre-established information sheet comprising 27 questions exploring sociodemographic and family data and specific data relating to the COVID-19 pandemic. The Arabic version of The Child PTSD Symptom Scale (CPSS) was used to screen for PTSD symptoms.Results326 adolescents were collected which the mean age was 16.6 years (14 to 18 years). The family environment was conflictual in 11.9% of cases. Among the adolescents, 5.5% had a history of somatic pathology. A history of psychiatric pathology was noted in 0.6%, dominated by depression. Personal infection by Covid-19 was noted in 4% of adolescents. A family member was affected in 27.3% of cases. Adolescents were exposed to the death of a close relative in 22.4% of cases. PTSD was diagnosed (according to the CPSS) in 37.4% of cases, with mild severity in 6.5%, moderate in 0.6%, moderately severe in 8%, severe in 5.2% and extremely severe in 17.2%. The analytical study showed that PTSD was correlated with a conflictual family environment (p=0.017), personal infection by COVID (P=0.003), infection of a close relative by COVID (P<0.001) and the death of a close relative by COVID (p<0.001).ConclusionsAccording to our study, the frequency of post-traumatic stress disorder among adolescents during the COVID-19 pandemic was high, underlining the need to screen at-risk populations for populations for early intervention.Disclosure of InterestNone Declared
Resilience among Tunisian adolescents during the COVID19 pandemic: about 326 cases
Authors: Mayssa K. , Jaweher B. , Ali K. , Khaoula K. , Donia B. T. , Imen H. , Hela A. , Yousr M. 
Published: August 2024

IntroductionThe COVID-19 pandemic has caused psychological distress in all the communities and through all ages. Some people seemed to be less affected and to be resilient because of a dynamic interaction between individual, relational and environmental factors.ObjectivesWe aim on this present study to evaluate the resilience and factors associated with it among a representative sample of Tunisian adolescents during the COVID19 pandemic.MethodsWe conducted a cross sectional, descriptive and analytic study among Tunisian adolescents enrolled in secondary schools, in the Hamma region of the city of Gabes during the period extending from 5 March to 26 May 2021. Students were asked to complete a pre-established questionnaire, which contains questions about socio demographic features, medical history and knowledge about the pandemic of covid-19. The Child and Youth Resilience Measure (CYRM-28) was used to evaluate the global resilience and resources contributing to it. The CYRM-28 contains three resources including individual, relationship with primary caregivers and contextual factors. Higher scores reflect higher levels of factors associated with resilience.ResultsA total of 326 adolescents aged between 14 and 18 years old participated on this study (mean age 16.65 years 1). There were 92 boys and 234 girls. In our sample, 4% of adolescents were infected by the Covid-19. The infection of a family member by this virus was noted in 27.3 % of cases. Adolescents were exposed to the death of a family member by Covid-19 in 22.4% of cases. The Global CYRM28 score was 105 ± 22.39. We found that adolescents who had loosen a family member because of the COVID infection, were less resilient than others (100 vs 107; p=0.023). Adolescents with a moderate to low socioeconomic level were less resilient especially with regard to contextual resilience (35, 57 vs 37, 83; p= 0.019). On the other hand, adolescents keeping means of leisure during this epidemic were significantly more resilient especially in the personal resources (p = 0.024).ConclusionsOur findings conclude to some individual, relational and contextual factors that contribute or alters the process of resilience. Recognizing the strengths and capacities of adolescents would allow the development of programs and resources that can help these young people develop resilience skills.Disclosure of InterestNone Declared
Psychopharmacological factor in the course of COVID-19 among psychiatric inpatients
Authors: Sorokin M. , Shabelnik A. , Bocharova M. , Lutova N. , Limankin O. , Azarova L. , Neznanov N. 
Published: August 2024

IntroductionIt is known that many psychopharmacological drugs have anti-inflammatory, as well as antibacterial and antiviral effects.ObjectivesTo investigate the association between the severity and duration criteria of COVID-19 with psychopharmacotherapy in double-diagnosed patients.MethodsA total of 169 case histories from a specialized infectious psychiatric department (May 2020 to January 2021) were evaluated. Progression indicators of severe and mild COVID-19, along with the duration of persistent SARS-CoV-2 viral shedding, were assessed in correlation with the administration of antidepressants, antipsychotics, and acid sphingomyelinase inhibitors (FIASMA-active drugs).ResultsThe use of any psychotropic agents was associated with a 0.9% increase in the risk of severe course of COVID-19 for each unit increase in the systemic inflammation index PLR, specifically in patients with intellectual disability (ICD-10 codes F70-79), when compared to patients with schizophrenia (ICD-10 codes F20-29): R²McF=0.138; AIC=181; χ²=25.8; df=9; p=0.002. High PLR values and the use of FIASMA-active drugs were associated with prolonged COVID-19 duration, while antidepressant therapy and elevated C-reactive protein levels were associated with a reduced predicted duration of viral shedding in 13.8% of variance: R²=0.0864; AIC=1299; F=5.2(3), p=0.002. Including the nosology of psychiatric disorders in the regression model increased the proportion of explained variance to 22.8%.ConclusionsThymoanaleptic therapy for individuals with psychiatric disorders may act as a protective factor against COVID-19. There is no evidence suggesting adverse effects of antipsychotics on the severity and duration of COVID-19. Further research is necessary to investigate the effects of FIASMA-active psychopharmacological agents within nosologically homogeneous groups.Disclosure of InterestNone Declared
Investigation of the factor structure of GAD-7 in Moscow residents exposed to SARS-CoV2
Authors: Zinchuk M. , Kustov G. , Nadezhda V. , Razmakhnin A. , Zhuravlev D. , Akzhigitov R. , Guekht A. 
Published: August 2024

IntroductionRates of anxiety in the general population increased significantly during the COVID-19 pandemic. Several studies have shown that people exposed to SARS-CoV2 are at increased risk for both exacerbation and de novo development of anxiety disorders. Therefore, screening for anxiety disorders in this at-risk population is essential. In pre-pandemic studies, the 7-item Generalized Anxiety Disorder Questionnaire (GAD-7) was one of the most commonly used self-report instruments. Its validity has been demonstrated in several studies. However, there is no agreement among researchers about its underlying internal structure. Both one-factor and two-factor solutions have been reported. This discrepancy may be due to linguistic, cultural, and clinical differences between the populations studied. To our knowledge, no studies have been conducted to investigate the factor structure of the GAD-7 in the Russian-speaking community sample and the psychometric properties of this questionnaire in SARS-CoV2 exposed individuals.ObjectivesThe aim of the study was to determine the factorial structure and internal consistency of the Russian version of the GAD-7 in a large sample of Moscow residents exposed to SARS-CoV2.MethodsFourteen thousand 725 (male - 11479 (78.0%), age - 18-79 years (M - 47.09, SD - 12.70) Moscow residents exposed to SARS-CoV2 completed an online survey including the GAD-7 and an ad hoc questionnaire focusing on socio-demographic characteristics. McDonald’s Omega was used to assess internal consistency. Exploratory structural equation modelling (ESEM) with weighted least squares means and variance adjusted estimator and geomin rotation was used to assess the factor structure of the Russian version of the GAD-7.ResultsThe McDonald’s Omega of the Russian version of the GAD-7 was 0.85, indicating a good internal consistency of the questionnaire. ESEM provided evidence for a one-factor solution that fits the data well (CFI - 0.996; TLI - 0.995; RMSEA (95% CI) - 0.041 (0.037 - 0.045)).ConclusionsIn Russian people exposed to SARS-CoV2, the GAD-7 showed good internal consistency. Our results are consistent with those of previous studies that reported a single-factor solution for the questionnaire.Disclosure of InterestNone Declared
The Parent Attitudes about Childhood Vaccination against COVID-19 in Tunisia
Authors: Bouguerra I. , Touiti A. , Askri W. , Hlayem S. , Bouden A. 
Published: August 2024

IntroductionThe vaccination of children and adolescents against covid 19 is an ongoing debate. While in some countries the program of vaccination of children under 12 years old is already implemented, in others the balance of risk and benefits is a dilemma. Parents’ perception and decision about covid vaccination is an important parameter to consider.ObjectivesThe ain of this study is to evaluate the parents’ attitude about childhood vaccination against Covid 19 in Tunisia.MethodsThe “vaccine hesitancy scale (VHS) adopted from WHO’s Strategic Advisory Group of Immunization” with 8 items translated in tunisian dialect and an additional ten survey idem about the Characteristics of parents and their vaccination status against Covid 19. The survey is distributed on social media groups of parents of tunisian children and adolescents.ResultsThirty parents have answered the survey.More than 80% of the participants were female with an average age of 38 years old.Among 30 participants 24 were vaccinated against covid 19 at least for once, but only one of them 10% decided to vaccinate their children against covid 19,while 3% are indecisive about the subject.Although 97 % of the children and adolescents have already been vaccinated completely according to the national vaccination program. The most common reasons for the refusal were.Parents consider that routine childhood vaccines are safe, necessary and useful more than covid vaccine. Some parents reported that their children have been infected by the virus so they have doubts about the usefulness of the vaccination.ConclusionsA year after the pandemic, covid 19 contamination and vaccination against the virus are still an issue. With the emergence of new variants, the decline in protective measures, vaccination against covid is in the process of integrating routine programs. But the lack of information on the effectiveness of the vaccine and the adverse effects are a source of hesitation and refusal for parents. a large-scale national study is necessary before.Disclosure of InterestNone Declared