bluuebunny/crossref_metadata_2025_split huggingface dataset:
Contribution of oxidation reactions to photo‐induced damage to cellular DNA
Authors: Cadet Jean , Angelov Dimitar , Di Mascio Paolo , Wagner J. Richard 
Published: July 2024

AbstractThis review article is aimed at providing updated information on the contribution of immediate and delayed oxidative reactions to the photo‐induced damage to cellular DNA/skin under exposure to UVB/UVA radiations and visible light. Low‐intensity UVC and UVB radiations that operate predominantly through direct excitation of the nucleobases are very poor oxidizing agents giving rise to very low amounts of 8‐oxo‐7,8‐dihydroguanine and DNA strand breaks with respect to the overwhelming bipyrimidine dimeric photoproducts. The importance of these two classes of oxidatively generated damage to DNA significantly increases together with a smaller contribution of oxidized pyrimidine bases upon UVA irradiation. This is rationalized in terms of sensitized photooxidation reactions predominantly mediated by singlet oxygen together with a small contribution of hydroxyl radical that appear to also be implicated in the photodynamic effects of the blue light component of visible light. Chemiexcitation‐mediated formation of “dark” cyclobutane pyrimidine dimers in UVA‐irradiated melanocytes is a recent major discovery that implicates in the initial stage, a delayed generation of reactive oxygen and nitrogen species giving rise to triplet excited carbonyl intermediate and possibly singlet oxygen. High‐intensity UVC nanosecond laser radiation constitutes a suitable source of light to generate pyrimidine and purine radical cations in cellular DNA via efficient biphotonic ionization.
Event‐related potentials of social comparisons in depression and social anxiety
Authors: Paz Valentina , Nicolaisen‐Sobesky Eliana , Fernández‐Theoduloz Gabriela , Pérez Alfonso , Cervantes Constantino Francisco , Martínez‐Montes Eduardo , Kessel Dominique , Cabana Álvaro , Gradin Victoria B. 
Published: July 2024

AbstractSocial comparison is central in human life and can be especially challenging in depression and social anxiety. We assessed event‐related potentials and emotions using a social comparison task in which participants received feedback on both their own and a co‐player's performance, in participants with depression and/or social anxiety (n = 63) and healthy controls (n = 72). Participants reported more negative emotions for downward (being better than the co‐player [participant correct, co‐player wrong]) and upward (being worse than the co‐player [participant wrong, co‐player correct]) comparisons versus even outcomes, with these effects being stronger in depression and social anxiety. At the Medial Frontal Negativity, both controls and depressed participants showed a more negative amplitude for upward comparison versus both the participant and co‐player performing wrong. Socially anxious subjects showed the opposite effect, possibly due to greater expectations about being worse than others. The P300 decreased for downward and upward comparisons compared to even outcomes, which may relate to the higher levels of conflict of social inequality. Depressed and socially anxious subjects showed a blunted P300 increase over time in response to the task outcomes, suggesting deficits in allocating resources for the attention of incoming social information. The LPP showed increased amplitude for downward and upward comparison versus the even outcomes and no group effect. Emotional findings suggest that social comparisons are more difficult for depressed and socially anxious individuals. Event‐related potentials findings may shed light on the neural substrates of these difficulties.
LiDAR and maps blend for rural decision support
Authors: Marković Viktor , Potić Ivan , Đorđević Dejan , Stojković Sanja , Drobnjak Siniša 
Published: July 2024

AbstractThis study integrates aerial LiDAR data and 2D cartographic information to rapidly develop an advanced non‐photorealistic rendering (NPR) model for rural environment analysis. The focus is enhancing decision support in crises and assessing potential hazards in these territories. The methodology involves capturing LiDAR data from high altitudes and classifying it as Ground, Vegetation, and Buildings. The integration of this data with 2D cartographic information, augmented with attribute data from a GIS database, is achieved through a semi‐automatic process. This process facilitates the creation of detailed 3D models, providing a more nuanced, visually and semantically rich representation of the rural landscape. The study underscores the benefits of combining LiDAR, photogrammetric, and cartographic data for creating accurate and detailed models of the rural environment, which are crucial for effective decision‐making and threat assessment.
Deciphering salt stress responses in Solanum pimpinellifolium through high‐throughput phenotyping
Authors: Morton Mitchell , Fiene Gabriele , Ahmed Hanin Ibrahim , Rey Elodie , Abrouk Michael , Angel Yoseline , Johansen Kasper , Saber Noha O. , Malbeteau Yoann , Al‐Mashharawi Samir , Ziliani Matteo G. , Aragon Bruno , Oakey Helena , Berger Bettina , Brien Chris , Krattinger Simon G. , Mousa Magdi A. A. , McCabe Matthew F. , Negrão Sónia , Tester Mark , Julkowska Magdalena M. 
Published: July 2024

SUMMARYSoil salinity is a major environmental stressor affecting agricultural productivity worldwide. Understanding plant responses to salt stress is crucial for developing resilient crop varieties. Wild relatives of cultivated crops, such as wild tomato, Solanum pimpinellifolium, can serve as a useful resource to further expand the resilience potential of the cultivated germplasm, S. lycopersicum. In this study, we employed high‐throughput phenotyping in the greenhouse and field conditions to explore salt stress responses of a S. pimpinellifolium diversity panel. Our study revealed extensive phenotypic variations in response to salt stress, with traits such as transpiration rate, shoot mass, and ion accumulation showing significant correlations with plant performance. We found that while transpiration was a key determinant of plant performance in the greenhouse, shoot mass strongly correlated with yield under field conditions. Conversely, ion accumulation was the least influential factor under greenhouse conditions. Through a Genome Wide Association Study, we identified candidate genes not previously associated with salt stress, highlighting the power of high‐throughput phenotyping in uncovering novel aspects of plant stress responses. This study contributes to our understanding of salt stress tolerance in S. pimpinellifolium and lays the groundwork for further investigations into the genetic basis of these traits, ultimately informing breeding efforts for salinity tolerance in tomato and other crops.
Screening, genotyping and haematological analysis of glucose‐6‐phosphate dehydrogenase deficiency in the blood donors of Wuxi City, China
Authors: Jin Jianhuai , Jiang Jian , Xu Youshan , Gao Li , Sun Wenhui , Jiang Ruixin , Gao Jing 
Published: July 2024

AbstractBackground and ObjectivesTo investigate the prevalence, genotype and haematological characteristics of glucose‐6‐phosphate dehydrogenase (G6PD) deficiency in the blood donor population of Wuxi area (Jiangsu Province, China) and to assess the impact of their red blood cell (RBC) units on clinical transfusion.Materials and MethodsWe conducted genotyping and large‐scale screening for G6PD enzyme activity in the blood donors of Wuxi City. In addition, we assessed the haematological parameters of G6PD‐deficient and non‐deficient blood donors, and investigated the adverse transfusion reactions in patients transfused with G6PD‐deficient blood.ResultsWe investigated 17,113 blood donors, among whom 44 (0.26%) were tested positive for G6PD deficiency. We identified 40 G6PD gene variants, among which c.1388G>A, c.1376G>T, c.1024C>T and c.95A>G were common. In addition, we identified two novel G6PD gene variants, c.1312G>A and c.1316G>A. The G6PD‐deficient and non‐deficient blood samples showed a significant difference in the RBC, mean corpuscular volume (MCV), mean corpuscular Hb (MCH), RBC distribution width, total bilirubin (TBIL), direct bilirubin (DBIL) and indirect bilirubin (IBIL) values. However, the two samples showed no significant difference in the haemolysis rate at the end of the storage period. Finally, transfusion with G6PD‐deficient RBC units did not lead to any adverse transfusion reactions.ConclusionThe positive rate of G6PD deficiency in the blood donor population of Wuxi City is 0.26%, and the genetic variants identified in this population are consistent with the common genetic variants observed in the Chinese population. Blood centres can establish a database on G6PD‐deficient blood donors and mark their RBC units to avoid their use for special clinical patients.
Rearrangement inequalities on the lattice graph
Authors: Gupta Shubham , Steinerberger Stefan 
Published: July 2024

AbstractThe Polya–Szegő inequality in states that, given a nonnegative function , its spherically symmetric decreasing rearrangement is ‘smoother’ in the sense of for all . We study analogues on the lattice grid graph . The spiral rearrangement is known to satisfy the Polya–Szegő inequality for , the Wang‐Wang rearrangement satisfies it for and no rearrangement can satisfy it for . We develop a robust approach to show that both these rearrangements satisfy the Polya–Szegő inequality up to a constant for all . In particular, the Wang‐Wang rearrangement satisfies for all . We also show the existence of (many) rearrangements on such that for all .
Post‐exercise hot or cold water immersion does not alter perception of effort or neuroendocrine responses during subsequent moderate‐intensity exercise
Authors: Menzies Campbell , Clarke Neil D. , Pugh Christopher J. A. , Steward Charles J. , Thake C. Douglas , Cullen Tom 
Published: July 2024

AbstractPost‐exercise hot (HWI) and cold (CWI) water immersion are popular strategies used by athletes in a range of sporting contexts, such as enhancing recovery or adaptation. However, prolonged heating bouts increase neuroendocrine responses that are associated with perceptions of fatigue. Fourteen endurance‐trained runners performed three trials consisting of two 45‐min runs at 95% lactate threshold on a treadmill separated by 6 h of recovery. Following the first run, participants completed one of HWI (30 min, 40°C), CWI (15 min, 14°C) or control (CON, 30 min rest in ambient conditions) in a randomised order. Perceived effort and recovery were measured using ratings of perceived exertion (RPE) and the Acute Recovery and Stress Scale (ARSS), whilst physiological responses including venous concentrations of a range of neuroendocrine markers, superficial femoral blood flow, heart rate and rectal temperature were measured. Exercise increased neuroendocrine responses of interleukin‐6, adrenaline and noradrenaline (all P < 0.001). Additionally, perceptions of overall recovery (P < 0.001), mental performance capacity (P = 0.02), physical performance capability (P = 0.01) and emotional balance (P = 0.03) were reduced prior to the second run. However, there was no effect of condition on these variables (P > 0.05), nor RPE (P = 0.68), despite differences in rectal temperature, superficial femoral blood flow following the first run, and participants’ expected recovery prior to the intervention (all P < 0.001). Therefore, athletes may engage in post‐exercise hot or cold‐water immersion without negatively impacting moderate‐intensity training sessions performed later the same day.
Spectra of $${Z}$$ Bosons and Lepton Angular Coefficients in the Leading Approximation of the Parton Reggeization Approach with Allowance for the Next-to-Leading-Order Corrections
Authors: Omelyanchuk S. S. , Saleev V. A. , Shipilova A. V. 
Published: July 2024

Abstract
The production of $$Z$$ bosons in proton–proton collisions and the LHC energies is studied. The production cross sections for $$Z$$ bosons and their transverse-momentum spectra are calculated along with the lepton angular coefficients as functions of the $$Z$$-boson transverse momentum. The calculations are performed within the parton Reggeization approach in the leading-order approximation in the strong coupling constant $$(Q\bar{Q}\to Z)$$ and with allowance for the next-to-leading-order correction associated with Reggeized-quark scattering on a Reggeized gluon $$(RQ\to Zq)$$. A numerical simulation is performed by means of the KaTie Monte Carlo generator. The results of the calculations are compared with experimental data of the ATLAS Collaboration.
Determination of Asymptotic Normalization Coefficients by Analytic Continuation of the $${R}$$-Matrix
Authors: Blokhintsev L. D. , Savin D. A. 
Published: July 2024

Abstract
The method of finding the values of asymptotic normalization coefficients (ANC) is proposed based on the analytic continuation of the $$R$$-matrix that describes the elastic nuclear scattering into the unphysical region of the negative energy of collision ($$E<0$$). The formula is derived, expressing the partial-wave scattering amplitude through the $$R$$-matrix and modified Coulomb functions. This formula allows, when continuing the amplitude to the region $$E<0$$, to overcome difficulties associated with irregular behavior of the scattering amplitude near $$E=0$$ if the Coulomb interaction is present. The proposed method is used to determine the ANC for the channel $${}^{16}\textrm{O}\to\alpha+{}^{12}$$C.
Insightful inspection of the nonlinear instability of an azimuthal disturbance separating two rotating magnetic liquid columns
Authors: Moatimid Galal M. , Mohamed Mona A. A. , Elagamy Khaled 
Published: July 2024

AbstractThe nonlinear stability examination of two revolving magnetized liquid columns connecting two completely submerged fluids in a permeable region is the aim of the existing paper. Two endless vertical cylinders occupied with two magnetic fluids make up the present structure. Significantly, the disturbance at the border displays an azimuthal behavior. The entire structure is activated by an azimuthal unchanging magnetic field (MF). The increasing interest in the atmospheric and oceanic dynamics is the primary motivation in exploring this problem. To relax the complication of the mathematical processes, the viscous potential theory (VPT) is established. The motion is assessed using three basic coexistent field formulations: Maxwell's formula, Brinkman's formula, and the continuity condition, in the construction of the Coriolis force and centrifugal implications. The explanations of the linearized formula of motion produce a nonlinear categorizing diffusion structure because of the implications of the nonlinear boundary conditions (BCs). The non-perturbative approach (NPA) based on the He's frequency formulation (HFF) is employed to transform the nonlinear characteristic ordinary differential equation (ODE) into a linear one. A short description of the NPA is also presented. The nonlinear ODE with real and imaginary coefficients is exposed by the stability analysis. The stability requirements are implemented using only a nonlinear analysis. As demonstrated, as an unusual state, it is exposed that ignoring the Weber number removes all complex items of the nonlinear formulation. Physically, this means the absence of the angular velocities from the physical model. For both the real and complex situations of the original equation, the stability remains unchanged. It is found that the azimuthal MF, rotating parameter, and Darcy’s numeral have a maintenance impact. On the other hand, the azimuthal wave numeral has a destabilizing one. Several polar designs are drawn to agreement the stability situations.
Clonal Lineage Tracing with Somatic Delivery of Recordable Barcodes Reveals Migration Histories of Metastatic Prostate Cancer
Authors: Serio Ryan N. , Scheben Armin , Lu Billy , Gargiulo Domenic V. , Patruno Lucrezia , Buckholtz Caroline L. , Chaffee Ryan J. , Jibilian Megan C. , Persaud Steven G. , Staklinski Stephen J. , Hassett Rebecca , Brault Lise M. , Ramazzotti Daniele , Barbieri Christopher E. , Siepel Adam C. , Nowak Dawid G. 
Published: July 2024

Abstract
The patterns by which primary tumors spread to metastatic sites remain poorly understood. Here, we define patterns of metastatic seeding in prostate cancer using a novel injection-based mouse model—EvoCaP (Evolution in Cancer of the Prostate), featuring aggressive metastatic cancer to bone, liver, lungs, and lymph nodes. To define migration histories between primary and metastatic sites, we used our EvoTraceR pipeline to track distinct tumor clones containing recordable barcodes. We detected widespread intratumoral heterogeneity from the primary tumor in metastatic seeding, with few clonal populations instigating most migration. Metastasis-to-metastasis seeding was uncommon, as most cells remained confined within the tissue. Migration patterns in our model were congruent with human prostate cancer seeding topologies. Our findings support the view of metastatic prostate cancer as a systemic disease driven by waves of aggressive clones expanding their niche, infrequently overcoming constraints that otherwise keep them confined in the primary or metastatic site.
Significance: Defining the kinetics of prostate cancer metastasis is critical for developing novel therapeutic strategies. This study uses CRISPR/Cas9-based barcoding technology to accurately define tumor clonal patterns and routes of migration in a novel somatically engineered mouse model (EvoCaP) that recapitulates human prostate cancer using an in-house developed analytical pipeline (EvoTraceR).
Dual polarity open circuit voltage in triboelectric nanogenerators originated from two states series impedance
Authors: Jeong Jiwon , Ko Jiyoung , Lee Jongjin 
Published: July 2024

AbstractExperimental and simulation studies demonstrated that the initial voltage setting significantly influences the open-circuit voltage (VOC) in triboelectric nanogenerators (TENGs). Utilizing diode configurations, we consistently observed two distinct VOCs independent of the initial settings. A lower VOC corresponded to the surface voltage (VSurface), while a higher VOC was amplified by the product of the VSurface and the TENG's characteristic impedance ratio. Notably, a lower measurement system capacitance provided a more precise representation of the inherent characteristics of the TENG. Conversely, an increase in system impedance led to a convergence of the two VOCs and a reduction in their magnitudes relative to VSurface. These findings suggest that optimizing the initial/repeated charge balancing and minimizing capacitive loads are crucial for maximizing TENG output power in practical applications.
A review of plastic waste nanocomposites: assessment of features and applications
Authors: Rasilainen Ida , Lahtela Ville , Kärki Timo 
Published: July 2024

AbstractHundreds of millions of metric tons of plastic waste are generated globally every year. Processing waste into secondary raw material is preferred over energy production and landfilling. However, mechanical recycling generally deteriorates the properties of plastic waste limiting its range of potential applications. Nanocomposite fabrication is a solution to recycle plastic waste into value-added applications due to improved properties generated by nanomaterial reinforcement, however received little study. The aim of this review is to present the current status, identify research gaps and provide topics for further research of polymer nanocomposites prepared from plastic waste in respect to utilized materials, processing methods, enhanced properties, sustainability, economics, nanomaterial safety, and applications. It is found that morphological, mechanical, thermal, flame retardancy, physical, barrier, electrical and shielding properties of plastic waste can be enhanced with low loadings of different nanomaterials making them promising materials for various applications including electronic, shielding, thermal, packaging, filtration, and water treatment. Utilization of plastic waste instead of virgin polymers can be beneficial in respect to economics and sustainability, but the energy intensive and expensive production of the most nanomaterials, and the plastic waste pretreatment methods can negate these benefits. To enhance sustainability, further research should be conducted on utilization of energy friendly nanomaterials in plastic waste nanocomposites. Further research is needed also on polymer nanocomposite safety because of the unknow composition of the plastic waste and the potential for nanomaterial release during nanocomposite’s life cycle. All in all, further research and national regulations and guidance are needed on virgin polymer and plastic waste nanocomposites.
Horizontal gene transfer of the Mer operon is associated with large effects on the transcriptome and increased tolerance to mercury in nitrogen-fixing bacteria
Authors: Bhat Aditi , Sharma Reena , Desigan Kumaran , Lucas M. Mercedes , Mishra Ankita , Bowers Robert M. , Woyke Tanja , Epstein Brendan , Tiffin Peter , Pueyo José J. , Paape Tim 
Published: July 2024

Abstract
Background
Mercury (Hg) is highly toxic and has the potential to cause severe health problems for humans and foraging animals when transported into edible plant parts. Soil rhizobia that form symbiosis with legumes may possess mechanisms to prevent heavy metal translocation from roots to shoots in plants by exporting metals from nodules or compartmentalizing metal ions inside nodules. Horizontal gene transfer has potential to confer immediate de novo adaptations to stress. We used comparative genomics of high quality de novo assemblies to identify structural differences in the genomes of nitrogen-fixing rhizobia that were isolated from a mercury (Hg) mine site that show high variation in their tolerance to Hg.

Results
Our analyses identified multiple structurally conserved merA homologs in the genomes of Sinorhizobium medicae and Rhizobium leguminosarum but only the strains that possessed a Mer operon exhibited 10-fold increased tolerance to Hg. RNAseq analysis revealed nearly all genes in the Mer operon were significantly up-regulated in response to Hg stress in free-living conditions and in nodules. In both free-living and nodule environments, we found the Hg-tolerant strains with a Mer operon exhibited the fewest number of differentially expressed genes (DEGs) in the genome, indicating a rapid and efficient detoxification of Hg from the cells that reduced general stress responses to the Hg-treatment. Expression changes in S. medicae while in bacteroids showed that both rhizobia strain and host-plant tolerance affected the number of DEGs. Aside from Mer operon genes, nif genes which are involved in nitrogenase activity in S. medicae showed significant up-regulation in the most Hg-tolerant strain while inside the most Hg-accumulating host-plant. Transfer of a plasmid containing the Mer operon from the most tolerant strain to low-tolerant strains resulted in an immediate increase in Hg tolerance, indicating that the Mer operon is able to confer hyper tolerance to Hg.

Conclusions
Mer operons have not been previously reported in nitrogen-fixing rhizobia. This study demonstrates a pivotal role of the Mer operon in effective mercury detoxification and hypertolerance in nitrogen-fixing rhizobia. This finding has major implications not only for soil bioremediation, but also host plants growing in mercury contaminated soils.