bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Photoinduced Radical Hydroperfluoroalkylation and the Synthesis of Fluorinated Amino Acids and Peptides.
Authors: Yajima Tomoko , Yamaguchi Kanako , Hirokane Rie , Nogami Emiko 
Published: September 2013

AbstractThe title method easily converts N‐phthalimide‐dehydroamino acids to the corresponding fluorinated amino acids.
ChemInform Abstract: Fast and Efficient Bromination of Aromatic Compounds with Ammonium Bromide and Oxone.
Authors: Naresh Mameda , Kumar Macharla Arun , Reddy Marri Mahender , Swamy Peraka , Nanubolu Jagadeesh Babu , Narender Nama 
Published: September 2013

AbstractThe efficient reagent combination can be used for the monobromination of a variety of arenes with at least one electron‐donating substituent and neither a catalyst nor an additive is required.
ChemInform Abstract: I2/TBHP‐Mediated Reaction of Sulfonylhydrazides with Alkynes: Synthesis of (E)‐β‐Iodovinyl Sulfones.
Authors: Li Xiaoqing , Xu Xiangsheng , Shi Xinhua 
Published: September 2013

AbstractThe optimized conditions allow the preparation of highly functionalized products with excellent yields, if aromatic alkynes are used.
ChemInform Abstract: Asymmetric Cycloetherifications by Bifunctional Aminothiourea Catalysts: The Importance of Hydrogen Bonding.
Authors: Fukata Yukihiro , Miyaji Ryota , Okamura Takaaki , Asano Keisuke , Matsubara Seijiro 
Published: September 2013

AbstractVarious ring closures to oxygen heterocycles are carried out under the optimized conditions A).
ChemInform Abstract: Asymmetric Synthesis of 1,3‐Oxazolidines via Intramolecular Aza‐Michael Addition by Bifunctional Organocatalysts.
Authors: Fukata Yukihiro , Asano Keisuke , Matsubara Seijiro 
Published: September 2013

AbstractA novel method for the synthesis of optically active oxazolidines (24 examples) via a formal [3 + 2] cycloaddition in the presence of cinchonidine‐derived thiourea organocatalyst is given.
ChemInform Abstract: Montmorillonite K10 Clay Catalyzed Synthesis of 4‐Aryltetrahydropyrans: A One‐Pot, Multicomponent, Environmentally Friendly Prins—Friedel—Crafts‐Type Reaction.
Authors: Dintzner Matthew R. 
Published: September 2013

AbstractThe methodology represents a more environmentally and logistically friendly route to 4‐aryltetrahydropyrans and gives higher yields with ketones compared to previously reported strategies.
ChemInform Abstract: Synthesis and Antimicrobial Activity of New Substituted 5‐(Pyridine‐3‐yl)‐1,3,4‐thiadiazoles and Their Sugar Derivatives.
Authors: El‐Sayed Wael A. , Metwally Mohamed A. , Nada Doaa S. , Mohamed Asem A. , Abdel‐Rahman Adel A.‐H. 
Published: September 2013

AbstractNew substituted pyridinylthiadiazoles, their sugar hydrazones [cf.
ChemInform Abstract: Synthesis of New 3‐Heteroaryl‐2‐phenylquinolines and Their Pharmacological Activity as Antimicrobial Agents.
Authors: Benzerka Saida , Bouraiou Abdelmalek , Bouacida Sofiane , Roisnel Thierry , Bentchouala Chafia , Smati Farida , Carboni Bertrand , Belfaitah Ali 
Published: September 2013

AbstractA variety of new 3‐heteroaryl‐2‐phenylquinoline hybrids are synthesized using quinoline‐3‐carbaldehyde (III) as the key intermediate.
ChemInform Abstract: Synthesis and Suzuki—Miyaura Reactions of 3,6,8‐Tribromoquinoline: A Structural Revision.
Authors: Akrawi Omer A. , Mohammed Hamid H. , Langer Peter 
Published: September 2013

AbstractReaction of tetrahydroquinoline (I) with NBS is reinvestigated to give 3,6,8‐tribromoquinoline instead of the reported 4,6,8‐isomer.
ChemInform Abstract: Synthesis and Antimicrobial Activity of N‐[(2Z)‐3‐(4,6‐Substitutedpyrimidin‐2‐yl)‐4‐phenyl‐1,3‐thiazol‐2 (3H)‐ylidene]‐3,5‐dinitrobenzamide Analogues.
Authors: Saeed Sohail , Hussain Rizwan , Ali Muhammad 
Published: September 2013

AbstractA simple and straightforward procedure for the preparation of thiazole‐pyrimidine core derivatives (VI) is developed.
ChemInform Abstract: A Facile Microwave‐Assisted “One‐Pot” Synthesis of Piperazino Pyrimidinyl Acetamides, a Class of Hybrid Bis Heterocycles and Their Structural Elucidation Using NMR Spectral Techniques.
Authors: Kanagarajan V. , Ang How Ghee , Ng Siu Choon , Gopalakrishnan M. 
Published: September 2013

AbstractTitle compounds of type (IV) are prepared.
ChemInform Abstract: Heterogeneously Catalyzed Aerobic Cross‐Dehydrogenative Coupling of Terminal Alkynes and Monohydrosilanes by Gold Supported on OMS‐2.
Authors: Yamaguchi Kazuya , Wang Ye , Oishi Takamichi , Kuroda Yoshiyuki , Mizuno Noritaka 
Published: September 2013

AbstractThe cross‐dehydrogenative coupling of various terminal alkynes and monohydrosilanes efficiently proceeds in the presence of gold supported on a cryptomelane‐type manganese oxide‐based octahedral molecular sieve as catalyst and O2 as a terminal oxidant.
ChemInform Abstract: Catalyst‐Controlled Switchable Phosphination of α‐Diazoesters.
Authors: Jiang Honglai , Jin Hongming , Abdukader Ablimit , Lin Aijun , Cheng Yixiang , Zhu Chenjian 
Published: September 2013

AbstractThe course of the reaction between phosphonates (II) and α‐diazoesters (I) can be governed by the choice of catalyst.
ChemInform Abstract: Broensted Acid Catalyzed Intramolecular Hydroarylation for the Synthesis of Cycloalkenyl Selenides and Tellurides.
Authors: Eom Dahan , Park Sangjune , Park Youngchul , Lee Kooyeon , Hong Gilbert , Lee Phil Ho 
Published: September 2013

AbstractThe reaction of alkynyl selenides and tellurides is catalyzed by TfOH and affords the intramolecular hydroarylation products, occurring in a selective 6‐ and 7‐endo‐mode.
Graphics processing unit accelerated one‐dimensional blood flow computation in the human arterial tree
Authors: Itu Lucian , Sharma Puneet , Kamen Ali , Suciu Constantin , Comaniciu Dorin 
Published: September 2013

SUMMARYOne‐dimensional blood flow models have been used extensively for computing pressure and flow waveforms in the human arterial circulation. We propose an improved numerical implementation based on a graphics processing unit (GPU) for the acceleration of the execution time of one‐dimensional model. A novel parallel hybrid CPU–GPU algorithm with compact copy operations (PHCGCC) and a parallel GPU only (PGO) algorithm are developed, which are compared against previously introduced PHCG versions, a single‐threaded CPU only algorithm and a multi‐threaded CPU only algorithm. Different second‐order numerical schemes (Lax–Wendroff and Taylor series) are evaluated for the numerical solution of one‐dimensional model, and the computational setups include physiologically motivated non‐periodic (Windkessel) and periodic boundary conditions (BC) (structured tree) and elastic and viscoelastic wall laws. Both the PHCGCC and the PGO implementations improved the execution time significantly. The speed‐up values over the single‐threaded CPU only implementation range from 5.26 to 8.10 × , whereas the speed‐up values over the multi‐threaded CPU only implementation range from 1.84 to 4.02 × . The PHCGCC algorithm performs best for an elastic wall law with non‐periodic BC and for viscoelastic wall laws, whereas the PGO algorithm performs best for an elastic wall law with periodic BC. Copyright © 2013 John Wiley & Sons, Ltd.
Heiße Bemessung von Mauerwerk nach Eurocode 6
Authors: Schlundt Andreas 
Published: September 2013

AbstractMit Veröffentlichung des Nationalen Anhangs zum Eurocode 6 Teil 1‐2 im Juni 2013 liegen nunmehr auch alle Grundlagen für die heiße Bemessung von Mauerwerk nach dem Eurocode vor. Der Eurocode 6 kann damit in der Praxis vollumfänglich auf Grundlage der Gleichwertigkeitserklärung der Fachkommission Bautechnik angewendet werden. Trotz der Umstellung auf das europäische Konzept mit Einführung neu benannter Feuerwiderstandsklassen sind die bekannten Tabellen zur Ermittlung der Feuerwiderstandsdauer in Abhängigkeit der Wanddicke nahezu unverändert die maßgebenden Parameter auch bei der heißen Bemessung von Mauerwerk nach Eurocode 6. Die wenigen Änderungen und An‐passungen an den aktuellen Stand der Technik werden nachfolgend dargestellt und erläutert.Structural fire design of masonry according to Eurocode 6. Publicating the National Annex to Eurocode 6 Part 1‐2 in July 2013 all essentials of structural fire design of masonry due to Eurocode 6 are available now. In practice Eurocode 6 is now allowed to be used in full extent in accordance with the equivalent introduction of the Fachkommission Bautechnik. Despite the changes to the european concept with implementation of new fire resistance classifications the already known tables to determine the fire resistance class depending on the thickness of the wall are nearly unchanged the decisive parameters for structural fire design according to Eurocode 6 as well. In the following the few changes and conversions to the state of the art are illustrated and explained.
Aluminum Acetals in Organic Synthesis
Authors: Boussonnière Anne , Bénéteau Romain , Lebreton Jacques , Dénès Fabrice 
Published: September 2013

AbstractAluminum acetals are easily obtained from esters and lactones by reduction with aluminum hydrides. These thermally unstable tetrahedral intermediates have found applications in organic synthesis, with various methodologies taking advantage both of the stabilities of these aluminum species at low temperatures and of their tendencies to undergo rearrangement into the corresponding aldehydes. Efficient one‐pot transformations can be achieved from aluminum acetals under ionic and radical conditions. A comprehensive overview of the reactivity of these species, including the most recent advances in this field, is presented in this microreview.
A review of current information and communication technologies: can they be used to assess apathy?
Authors: König Alexandra , Aalten Pauline , Verhey Frans , Bensadoun Gregory , Petit Pierre‐David , Robert Philippe , David Renaud 
Published: September 2013

BackgroundNeuropsychiatric symptoms, such as apathy, have an important impact on the quality of life of both patients diagnosed with dementia and their caregivers and represent a strong predictor of progression of the illness. Current clinical assessment methods risk bias resulting from the assessor's subjectivity, pointing to a need for additional objective and systematic assessment tools. Therefore, the use of information and communication technologies (ICT) such as actigraphy and automatized video monitoring are of interest in addition to current assessment methods.AimThe goal of this study is to give an overview of current assessment tools for apathy in clinical practice and new approaches to assessment methods with the help ICT.MethodsThis study was conducted with the use of narrative literature overview.ResultsThere is evidence that apart from the currently used assessment methods for apathy, new ICT approaches could provide clinicians with valuable additional information for an earlier detection and therefore more accurate diagnosis of apathy.ConclusionsThere are no ICT techniques specifically designed for the assessment of apathy, but nevertheless several techniques seem to be promising and deserve more study. Copyright © 2013 John Wiley & Sons, Ltd.
Event‐related fMRI at 7T reveals overlapping cortical representations for adjacent fingertips in S1 of individual subjects
Authors: Besle Julien , Sánchez‐Panchuelo Rosa‐Maria , Bowtell Richard , Francis Susan , Schluppeck Denis 
Published: September 2013

AbstractRecent fMRI studies of the human primary somatosensory cortex have been able to differentiate the cortical representations of different fingertips at a single‐subject level. These studies did not, however, investigate the expected overlap in cortical activation due to the stimulation of different fingers. Here, we used an event‐related design in six subjects at 7 Tesla to explore the overlap in cortical responses elicited in S1 by vibrotactile stimulation of the five fingertips. We found that all parts of S1 show some degree of spatial overlap between the cortical representations of adjacent or even nonadjacent fingertips. In S1, the posterior bank of the central sulcus showed less overlap than regions in the post‐central gyrus, which responded to up to five fingertips. The functional properties of these two areas are consistent with the known layout of cytoarchitectonically defined subareas, and we speculate that they correspond to subarea 3b (S1 proper) and subarea 1, respectively. In contrast with previous fMRI studies, however, we did not observe discrete activation clusters that could unequivocally be attributed to different subareas of S1. Venous maps based on T2*‐weighted structural images suggest that the observed overlap is not driven by extra‐vascular contributions from large veins. Hum Brain Mapp 35:2027–2043, 2014. © 2013 The Authors Human Brain Mapping published by Wiley Periodicals, Inc.
Dopamine‐agonists and impulsivity in Parkinson's disease: Impulsive choices vs. impulsive actions
Authors: Antonelli Francesca , Ko Ji Hyun , Miyasaki Janis , Lang Anthony E. , Houle Sylvain , Valzania Franco , Ray Nicola J. , Strafella Antonio P. 
Published: September 2013

AbstractThe control of impulse behavior is a multidimensional concept subdivided into separate subcomponents, which are thought to represent different underlying mechanisms due to either disinhibitory processes or poor decision‐making. In patients with Parkinson's disease (PD), dopamine‐agonist (DA) therapy has been associated with increased impulsive behavior. However, the relationship among these different components in the disease and the role of DA is not well understood. In this imaging study, we investigated in PD patients the effects of DA medication on patterns of brain activation during tasks testing impulsive choices and actions. Following overnight withdrawal of antiparkinsonian medication, PD patients were studied with a H2 (15)O PET before and after administration of DA (1 mg of pramipexole), while they were performing the delay discounting task (DDT) and the GoNoGo Task (GNG). We observed that pramipexole augmented impulsivity during DDT, depending on reward magnitude and activated the medial prefrontal cortex and posterior cingulate cortex and deactivated ventral striatum. In contrast, the effect of pramipexole during the GNG task was not significant on behavioral performance and involved different areas (i.e., lateral prefrontal cortex). A voxel‐based correlation analysis revealed a significant negative correlation between the discounting value (k) and the activation of medial prefrontal cortex and posterior cingulate suggesting that more impulsive patients had less activation in those cortical areas. Here we report how these different subcomponents of inhibition/impulsivity are differentially sensitive to DA treatment with pramipexole influencing mainly the neural network underlying impulsive choices but not impulsive action. Hum Brain Mapp 35:2499–2506, 2014. © 2013 Wiley Periodicals, Inc.
The representation of oral fat texture in the human somatosensory cortex
Authors: Grabenhorst Fabian , Rolls Edmund T. 
Published: September 2013

AbstractHow fat is sensed in the mouth and represented in the brain is important in relation to the pleasantness of food, appetite control, and the design of foods that reproduce the mouthfeel of fat yet have low energy content. We show that the human somatosensory cortex (SSC) is involved in oral fat processing via functional coupling to the orbitofrontal cortex (OFC), where the pleasantness of fat texture is represented. Using functional MRI, we found that activity in SSC was more strongly correlated with the OFC during the consumption of a high fat food with a pleasant (vanilla) flavor compared to a low fat food with the same flavor. This effect was not found in control analyses using high fat foods with a less pleasant flavor or pleasant‐flavored low fat foods. SSC activity correlated with subjective ratings of fattiness, but not of texture pleasantness or flavor pleasantness, indicating a representation that is not involved in hedonic processing per se. Across subjects, the magnitude of OFC‐SSC coupling explained inter‐individual variation in texture pleasantness evaluations. These findings extend known SSC functions to a specific role in the processing of pleasant‐flavored oral fat, and identify a neural mechanism potentially important in appetite, overeating, and obesity. Hum Brain Mapp 35:2521–2530, 2014. © 2013 Wiley Periodicals, Inc.
Modeling activation and effective connectivity of VWFA in same script bilinguals
Authors: Boukrina Olga , Hanson Stephen Jose , Hanson Catherine 
Published: September 2013

AbstractPrevious neuroimaging research revealed a small area in the inferior occipito–temporal cortex (VWFA), which seems to be involved in recognition of written words. The specialized response of the VWFA to words could result from repeated exposure to print in the course of functional fine‐tuning of the brain. Research with bilingual speakers holds promise in helping to reveal response properties of the VWFA by assessing its sensitivity to language proficiency, word‐form similarity, and meaning overlap across two languages. Using fMRI, we compared VWFA activity for cognate and homograph prime‐target pairs in a group of fluent Spanish–English speakers. Cognates share form and meaning in two languages, while homographs only share form. Relative to baseline, the VWFA showed repetition suppression to pairs of homographs, but not to pairs of cognates, suggesting that this area is sensitive to word meaning. The different response to cognates and homographs was only observed when English was the prime language and Spanish was the target language. To help explain this result we compared patterns of effective connectivity between the VWFA and other parts of the reading network implicated in semantic and phonological processing. Our neural models showed that English targets engaged a direct ventral route from the VWFA to the frontal lobe and Spanish targets engaged an indirect dorsal route. Considering that frontal cortex has been implicated in semantic processing, a direct connection to this area could signal a fast and automatic access to meaning and would facilitate early semantic influences in visual word recognition. Hum Brain Mapp 35:2543–2560, 2014. © 2013 Wiley Periodicals, Inc.
Influence of ethnicity and improved outcome of acute myeloid leukaemia: two decades of follow‐up of Israeli patient cohort
Authors: Goldschmidt Neta , Cohen Sara B. , Gatt Moshe E. , Safrai Myriam , Rund Deborah 
Published: September 2013

AbstractAcute myeloid leukaemia is a disease with unfavourable prognosis. The significance of various prognostic parameters is not fully understood. We studied 293 patients to examine the influence of ethnicity and molecular markers. The median survival for all patients was correlated with age, white blood cell count and karyotype, and marginally with FLT3 internal tandem duplication. Arab patients were younger than Jewish patients; however, their survival was poorer albeit being treated with the same protocols and having more favourable cytogenetics. Survival rates improved over time but only for patients undergoing allogeneic bone marrow transplantation (alloBMT). We conclude that in our young patient cohort, recent improvement in survival is attributed to alloBMT therapy and that ethnicity affected treatment outcome. Copyright © 2013 John Wiley & Sons, Ltd.
The Difficulties in Emotion Regulation Scale: Factor Structure in Chronic Pain Patients
Authors: Kökönyei Gyöngyi , Urbán Róbert , Reinhardt Melinda , Józan Anna , Demetrovics Zsolt 
Published: September 2013

ObjectiveResearch suggests that emotions and emotion regulation processes can influence both the sensory (e.g., intensity) and the affective (unpleasantness) components of pain. The purpose of this study was to investigate the factor structure and validity of the Difficulties in Emotion Regulation Scale (DERS; Gratz and Roemer, 2004) in medical sample with persistent pain.MethodData were collected from 207 chronic pain patients (82.6% female; mean age = 51.96). We applied confirmatory factor analysis (CFA) to test measurement model of emotion dysregulation and CFA with covariates to test construct and convergent validity of the DERS.ResultsThe original factor structure of the DERS was not supported in our medical sample. However, after some modifications the DERS yielded good fit. Validity of the DERS was confirmed. All the subscales had significant relationship with depression measure, and all the subscales except one correlated with Difficulties in Identifying Feelings component of alexithymia.ConclusionsThe DERS proved to be an adequate measure of clinically relevant dimensions of emotional dysregulation in chronic pain patients.
Wnt16 is Involved in Intramembranous Ossification and Suppresses Osteoblast Differentiation Through the Wnt/β‐Catenin Pathway
Authors: Jiang Zheng , Von den Hoff Johannes W. , Torensma Ruurd , Meng Liuyan , Bian Zhuan 
Published: September 2013

AbstractIn the course of embryonic development skeletal elements form either through intramembranous or endochondral ossification. Wnt proteins play diverse roles during vertebrate skeletal development. Wnt16 is a key factor in developing long bones, but its exact role in craniofacial bone formation remains unclear. This study was initially undertaken to investigate the expression of Wnt16 during craniofacial bone development in mouse embryos. Wnt16 expression in the osteoid of calvaria, maxilla, and mandible started later than that of ALP and osteocalcin (OCN), but before mineralization of the craniofacial bones, suggesting that Wnt16 is involved in intramembranous ossification in the head. To confirm this, MC3T3‐E1 cells were transfected with an adenovirus containing Wnt16 (Ad‐Wnt16). Ad‐Wnt16 cells showed decreased ALP activity and less mineralized nodule formations compared with control cells. In addition, the mRNA levels of osteogenic markers were reduced. Moreover, Wnt16 activated β‐catenin signaling in MC3T3‐E1 cells at both transcription and protein levels as shown by a TOPflash luciferase reporter gene assay and western blot analysis. On the other hand, Wnt/β‐catenin pathway blockade by Dickkopf 1 abrogated the suppression of mineralization by Wnt16. Our findings suggest that Wnt16 is involved in intramembranous ossification and suppresses osteoblast differentiation through the Wnt/β‐catenin pathway. J. Cell. Physiol. 229: 384–392, 2014. © 2013 Wiley Periodicals, Inc.