bluuebunny/crossref_metadata_2025_split huggingface dataset:
Livestreamed tourism shopping: consumers’ attitudes and behaviors
Authors: Liu Chun , Zhao Qi , Gursoy Dogan , Zheng Hong 
Published: July 2024

Purpose
This study aims to investigate how source attractiveness (including platform credibility, product appeal and streamer attractiveness) and information quality impact viewers’ cognition and flow state. Additionally, it examines how these factors influence the development of consumer attitudes and behaviors toward livestreamed tourism shopping, as well as the moderating roles of perceived risk and personal characteristics.

Design/methodology/approach
A sequential mixed-methods research design was used. In addition to a literature review, 15 interviews were conducted to identify measurement items for the subsequent questionnaire survey. Sample 1 (n = 209) was used to refine these measurement items, whereas Sample 2 (n = 227) was used to evaluate the measurement model and test the proposed hypotheses.

Findings
Findings reveal that source attractiveness (streamer attractiveness, tourism product attractiveness and platform credibility) and information quality significantly influence customers’ behavior formation, with cognition and flow state acting as mediators. Findings further confirm the moderating effect of perceived risk in a livestreamed shopping environment.

Practical implications
The findings provide new insights into how consumers select livestreamed shopping platforms. As viewers assess the credibility and trustworthiness of each component to form their perception of the overall platform’s credibility, companies should market their products through credible platforms, studios and stores with extensive reach. It is also critical to collaborate with streamers who are sincere, trustworthy, knowledgeable and professional. Since perceived risk lowers consumer behavioral intentions, live streamers, platforms and merchants should offer convincing and credible arguments to alleviate viewers’ perceived risks.

Originality/value
This study advances the literature on livestreamed shopping by broadening the conceptualization of source attractiveness to include three dimensions: streamer attractiveness, product attractiveness and platform attractiveness. Furthermore, it differentiates itself from existing studies by integrating and adopting multidimensional measurements of cognition (perceived usefulness and ease of use) and flow state (control, enjoyment, curiosity and concentration).
Hydrocarbon Generation Potential and Organic Matter Enrichment Mechanism of the Cambrian Marine Shale in the Tadong Low Uplift, Tarim Basin
Authors: MIAO Huan , WANG Yanbin , JIANG Zhenxue , ZHAO Shihu , SHANG Peng , GONG Xun , TAO Chuanqi , ZHANG Yu 
Published: July 2024

AbstractCambrian shales in China and elsewhere contain abundant oil and gas resources. However, due to its deep burial and limited outcrop, there has been relatively little research conducted on it. The Cambrian shale of the Tadong low uplift in the Tarim Basin of western China, specifically the Xidashan–Xishanbulake Formation (Fm.) and overlying Moheershan Fm. provide a case study through the use of organic petrology, mineralogy, organic and elemental geochemistry, with the aim of analyzing and exploring the hydrocarbon generation potential (PG) and organic matter (OM) enrichment mechanisms within these shale formations. The results indicate that: (1) the Cambrian shale of the Tadong low uplift exhibits relatively dispersed OM that consists of vitrinite‐like macerals and solid bitumen. These formations have a higher content of quartz and are primarily composed of silica‐based lithology; (2) shale samples from the Xidashan–Xishanbulake and Moheershan formations demonstrate high total organic carbon (TOC) and low pyrolytic hydrocarbon content (S2) content. The OM is predominantly type I and type II kerogens, indicating a high level of maturation in the wet gas period. These shales have undergone extensive hydrocarbon generation, showing characteristics of relatively poor PG; (3) the sedimentary environments of the Xidashan–Xishanbulake and Moheershan formations in the Tadong low uplift are similar. They were deposited in warm and humid climatic conditions, in oxygen‐deficient environments, with stable terrigenous inputs, high paleoproductivity, high paleosalinity, weak water‐holding capacity, and no significant hydrothermal activity; and (4) the relationship between TOC and the paleoproductivity parameter (P/Ti) is most significant in the Lower Cambrian Xidashan–Xishanbulake Fm., whereas correlation with other indicators is not evident. This suggests a productivity‐driven OM enrichment model, where input of land‐derived material was relatively small during the Middle Cambrian, and the ancient water exhibited lower salinity. A comprehensive pattern was formed under the combined control of paleoproductivity and preservation conditions. This study provides valuable guidance for oil and gas exploration in the Tarim Basin.
Seasonal and interannual variability of the free‐living and particle‐associated bacteria of a coastal microbiome
Authors: Ferrera Isabel , Auladell Adrià , Balagué Vanessa , Reñé Albert , Garcés Esther , Massana Ramon , Gasol Josep M. 
Published: July 2024

AbstractMarine microbial communities differ genetically, metabolically, and ecologically according to their lifestyle, and they may respond differently to environmental changes. In this study, we investigated the seasonal dynamics of bacterial assemblies in the free‐living (FL) and particle‐associated (PA) fractions across a span of 6 years in the Blanes Bay Microbial Observatory in the Northwestern Mediterranean. Both lifestyles showed marked seasonality. The trends in alpha diversity were similar, with lower values in spring–summer than in autumn‐winter. Samples from both fractions were grouped seasonally and the percentage of community variability explained by the measured environmental variables was comparable (32% in FL and 31% in PA). Canonical analyses showed that biotic interactions were determinants of bacterioplankton dynamics and that their relevance varies depending on lifestyles. Time‐decay curves confirmed a high degree of predictability in both fractions. Yet, ‘seasonal’ Amplicon Sequence Variants (ASVs) (as defined by Lomb Scargle time series analysis) in the PA communities represented 46% of the total relative abundance while these accounted for 30% in the FL fraction. These results demonstrate that bacteria inhabiting both fractions exhibit marked seasonality, highlighting the importance of accounting for both lifestyles to fully comprehend the dynamics of marine prokaryotic communities.
Sex‐specific growth and lifespan effects of germline removal in the dioecious nematode Caenorhabditis remanei
Authors: Lind Martin I. , Mautz Brian S. , Carlsson Hanne , Hinas Andrea , Gudmunds Erik , Maklakov Alexei A. 
Published: July 2024

AbstractGermline regulates the expression of life‐history traits and mediates the trade‐off between reproduction and somatic maintenance. However, germline maintenance in itself can be costly, and the costs can vary between the sexes depending on the number of gametes produced across the lifetime. We tested this directly by germline ablation using glp‐1 RNA interference (RNAi) in a dioecious nematode Caenorhabditis remanei. Germline removal strongly increased heat‐shock resistance in both sexes, thus confirming the role of the germline in regulating somatic maintenance. However, germline removal resulted in increased lifespan only in males. High costs of mating strongly reduced lifespan in both sexes and obliterated the survival benefit of germline‐less males even though neither sex produced any offspring. Furthermore, germline removal reduced male growth before maturation but not in adulthood, while female growth rate was reduced both before and especially after maturation. Thus, germline removal improves male lifespan without major growth costs, while germline‐less females grow slower and do not live longer than reproductively functional counterparts in the absence of environmental stress. Overall, these results suggest that germline maintenance is costlier for males than for females in C. remanei.
Association of psychiatric and substance use disorders with cannabis use and cannabis use disorder during early pregnancy in northern California
Authors: Young‐Wolff Kelly C. , Chi Felicia W. , Campbell Cynthia I. , Does Monique B. , Brown Qiana L. , Alexeeff Stacey E. , Ansley Deborah , Wang Xiaoming , Lapham Gwen T. 
Published: July 2024

AbstractAimsTo estimate the strength of association between psychiatric disorders and substance use disorders (SUD), and cannabis use and cannabis use disorder (CUD) during early pregnancy.DesignObservational study.SettingKaiser Permanente Northern California, USA.Participants299 496 pregnancies from 227 555 individuals screened for cannabis use by self‐report and a urine toxicology test at entrance to prenatal care in Kaiser Permanente Northern California during January 2011–December 2021 (excepting year 2020). The sample was 62.5% non‐White, with a mean (standard deviation) age of 31.1 (5.5) years; 6.8% used cannabis; 0.2% had a CUD.MeasurementsExposure variables included electronic health record‐based psychiatric diagnoses of attention deficit hyperactivity, anxiety, bipolar, depressive, personality, posttraumatic stress and psychotic disorders; and alcohol, opioid, stimulant and tobacco use disorders, during the two years prior to pregnancy up to the day before the prenatal substance use screening date. Outcome variables were any cannabis use, frequency of self‐reported cannabis use and CUD during early pregnancy.FindingsPsychiatric disorder prevalence ranged from 0.2% (psychotic) to 14.3% (anxiety), and SUD ranged from 0.3% (stimulant/opioid) to 3.8% (tobacco). Psychiatric disorders were associated with cannabis use and CUD, with the strongest association for any use found for bipolar disorder (adjusted odds ratio [aOR] = 2.83; 95% confidence interval [CI] = 2.53–3.17) and the strongest association for CUD found for psychotic disorders (aOR = 10.01, 95% CI = 6.52–15.37). SUDs were associated with cannabis use and CUD, with the strongest association for any use found for tobacco use disorder (aOR = 4.03, 95% CI = 3.82–4.24) and the strongest association for CUD found for stimulant use disorder (aOR = 21.99, 95% CI = 16.53–29.26). Anxiety, bipolar, depressive disorders and tobacco use disorder were associated with greater odds of daily than monthly or less cannabis use.ConclusionsPsychiatric disorders and substance use disorders appear to be associated with elevated odds of any and frequent cannabis use as well as cannabis use disorder during early pregnancy. In most cases, the associations with cannabis outcomes were stronger for substance use disorders than other psychiatric disorders.
Review article: Oesophageal disorders in chronic liver disease
Authors: Idalsoaga Francisco , Díaz Luis Antonio , Ayares Gustavo , Cabrera Daniel , Chahuan Javier , Monrroy Hugo , Halawi Houssam , Arrese Marco , Arab Juan Pablo 
Published: July 2024

SummaryBackgroundOesophageal disorders and chronic liver disease are common worldwide and significantly impact quality of life. The intricate link between these conditions, including how oesophageal disorders like GERD, Barrett's oesophagus and oesophageal cancer affect and are affected by chronic liver disease, remains poorly understood.AimsTo review the relationship between oesophageal disorders and chronic liver disease, evaluating epidemiology, pathophysiology and therapeutic factors.MethodsWe reviewed the literature on the relationship between oesophageal disorders and chronic liver disease, including cirrhosis, using the PubMed databaseResultsOesophageal disorders such as gastroesophageal reflux disease, Barrett's oesophagus, oesophageal cancer, oesophageal motor disorders and oesophageal candidiasis are prevalent among individuals with cirrhosis, exacerbating the burden of liver disease. These diseases have a multifaceted symptomatology and pathogenic basis, posing a significant challenge in cirrhotic patients that necessitates careful diagnosis and management. Additionally, therapies frequently used for these diseases, such as proton pump inhibitors, require careful consideration in cirrhotic patients due to potential adverse effects and altered pharmacokinetics. Managing oesophageal disorders in cirrhotic patients requires a cautious approach due to possible interactions with medications and the risk of adverse effects. Furthermore, symptoms associated with these conditions are often exacerbated by common interventions in patients with cirrhosis, such as band ligation for oesophageal varices.ConclusionsOesophageal disorders are common in cirrhosis and increase the disease burden. These conditions require careful management due to complex symptoms and treatment risks. Proton pump inhibitors and other therapies must be used cautiously, as cirrhosis interventions can worsen symptoms.
Clinical outcomes of hypomethylating agents and venetoclax in newly diagnosed unfit and relapsed/refractory paediatric, adolescent and young adult acute myeloid leukaemia patients
Authors: LeBlanc Francis R. , Breese Erin H. , Burns Karen C. , Chang Ellen K. , Jones LaQuita M. , Lee Lynn , Mizukawa Benjamin , Norris Robin E. , O'Brien Maureen M. , Phillips Christine L. , Perentesis John P. , Rubinstein Jeremy , Pommert Lauren 
Published: July 2024

SummaryVenetoclax (VEN) combined with hypomethylating agents (HMA) decitabine or azacitidine is used for adult acute myeloid leukaemia (AML), but its application in paediatric, adolescent and young adult (AYA) AML lacks prospective studies. We performed a retrospective chart review of paediatric and AYA AML patients treated with HMA + VEN at Cincinnati Children's Hospital Medical Centre. Twenty‐seven patients received 30 HMA + VEN treatment courses for relapsed/refractory (R/R, n = 21) or newly diagnosed (n = 9) AML due to ineligibility for intensive chemotherapy. The R/R cohort had high‐risk cytomolecular genetic alterations and prior extensive treatments, with 50% (n = 9) of relapse patients (n = 18) having undergone haematopoietic stem cell transplantation (HSCT). Venetoclax treatment using the 400 mg adult exposure‐equivelant dosing (AED) had a median duration of 21 days (range 7–30 days). Grade 3–4 toxicities included neutropenia (90%), anaemia (64%), thrombocytopenia (64%) and febrile neutropenia (44%). The overall complete remission (CR)/CR with incomplete blood count recovery (CRi) rate was 73% (77% minimal residual disease [MRD] negativity <0.1%), with 60% undergoing HSCT. Among newly diagnosed patients (n = 9), 89% achieved CR/CRi (78% MRD negativity) and 78% proceeded to HSCT. The R/R cohort (n = 21) showed a 67% CR/CRi rate (71% MRD negativity), with 52% undergoing HSCT. These findings support the safety and efficacy of HMA + VEN in paediatric/AYA AML, indicating it as a viable option for patients unfit for intensive chemotherapy. Further studies are necessary to determine optimal venetoclax dosing, chemotherapy combinations and pharmacokinetics in this population.
Prognostic role of the neutrophil/lymphocyte ratio in high‐risk BCG‐naïve non‐muscle‐invasive bladder cancer treated with intravesical gemcitabine/docetaxel
Authors: Chakra Mohamad Abou , Lassila Riitta , El Beayni Nancy , Mott Sarah L. , O'Donnell Michael A. 
Published: July 2024

ObjectivesTo investigate the role of pretreatment neutrophil‐to‐lymphocyte ratio (NLR) and platelet‐to‐lymphocyte ratio (PLR) in the prediction of response to sequential intravesical therapy, gemcitabine and docetaxel (Gem/Doce), given to patients with bacille Calmette–Guérin (BCG)‐ naïve high‐risk non‐muscle‐invasive bladder cancer (NMIBC).Patients and MethodsA retrospective analysis was conducted on 115 patients who received intravesical Gem/Doce for high‐risk NMIBC between January 2011 and December 2021. Data were computed as the median (interquartile range [IQR]) or mean (standard deviation [sd]). Cox regression analysis was performed to determine if neutrophilia, NLR, platelet counts, and PLR before instillation therapy were predictive of recurrence‐free survival (RFS) and overall survival (OS). Predictive performance was estimated using Uno's C‐statistic.ResultsThe median (IQR) follow‐up for the overall cohort was 23 (13–36) months. The mean (sd) values for NLR, PLR and platelet counts were 3.4 (2.3), 142.2 (85.5), and 225.2 (75.1) × 109/L, respectively. NLR was associated with RFS, with a hazard ratio of 1.32 (95% confidence interval CI 1.19–1.46). Concordance analysis showed that NLR had a good ability to predict RFS (C‐index: 0.7, P < 0.01). The PLR and platelet count were not associated with RFS and did not predict recurrence. In terms of OS, none of these cellular inflammatory markers showed any prediction value.ConclusionPre‐treatment NLR provides some predictive accuracy for RFS in high‐risk BCG‐naïve patients receiving Gem/Doce. Further prospective trials are needed to validate this finding.
Optimized Dual‐Volumes for Tetrahedral Meshes
Authors: Jacobson Alec 
Published: July 2024

AbstractConstructing well‐behaved Laplacian and mass matrices is essential for tetrahedral mesh processing. Unfortunately, the de facto standard linear finite elements exhibit bias on tetrahedralized regular grids, motivating the development of finite‐volume methods. In this paper, we place existing methods into a common construction, showing how their differences amount to the choice of simplex centers. These choices lead to satisfaction or breakdown of important properties: continuity with respect to vertex positions, positive semi‐definiteness of the implied Dirichlet energy, positivity of the mass matrix, and unbiased‐ness on regular grids. Based on this analysis, we propose a new method for constructing dual‐volumes which explicitly satisfy all of these properties via convex optimization.
Search Me Knot, Render Me Knot: Embedding Search and Differentiable Rendering of Knots in 3D
Authors: Gangopadhyay Aalok , Gupta Paras , Sharma Tarun , Singh Prajwal , Raman Shanmuganathan 
Published: July 2024

AbstractWe introduce the problem of knot‐based inverse perceptual art. Given multiple target images and their corresponding viewing configurations, the objective is to find a 3D knot‐based tubular structure whose appearance resembles the target images when viewed from the specified viewing configurations. To solve this problem, we first design a differentiable rendering algorithm for rendering tubular knots embedded in 3D for arbitrary perspective camera configurations. Utilizing this differentiable rendering algorithm, we search over the space of knot configurations to find the ideal knot embedding. We represent the knot embeddings via homeomorphisms of the desired template knot, where the weights of an invertible neural network parametrize the homeomorphisms. Our approach is fully differentiable, making it possible to find the ideal 3D tubular structure for the desired perceptual art using gradient‐based optimization. We propose several loss functions that impose additional physical constraints, enforcing that the tube is free of self‐intersection, lies within a predefined region in space, satisfies the physical bending limits of the tube material, and the material cost is within a specified budget. We demonstrate through results that our knot representation is highly expressive and gives impressive results even for challenging target images in both single‐view and multiple‐view constraints. Through extensive ablation study, we show that each proposed loss function effectively ensures physical realizability. We construct a real‐world 3D‐printed object to demonstrate the practical utility of our approach.
Stability for Inference with Persistent Homology Rank Functions
Authors: Wang Qiquan , García‐Redondo Inés , Faugère Pierre , Henselman‐Petrusek Gregory , Monod Anthea 
Published: July 2024

AbstractPersistent homology barcodes and diagrams are a cornerstone of topological data analysis that capture the “shape” of a wide range of complex data structures, such as point clouds, networks, and functions. However, their use in statistical settings is challenging due to their complex geometric structure. In this paper, we revisit the persistent homology rank function, which is mathematically equivalent to a barcode and persistence diagram, as a tool for statistics and machine learning. Rank functions, being functions, enable the direct application of the statistical theory of functional data analysis (FDA)—a domain of statistics adapted for data in the form of functions. A key challenge they present over barcodes in practice, however, is their lack of stability—a property that is crucial to validate their use as a faithful representation of the data and therefore a viable summary statistic. In this paper, we fill this gap by deriving two stability results for persistent homology rank functions under a suitable metric for FDA integration. We then study the performance of rank functions in functional inferential statistics and machine learning on real data applications, in both single and multiparameter persistent homology. We find that the use of persistent homology captured by rank functions offers a clear improvement over existing non‐persistence‐based approaches.
Nutritional self‐management in colorectal cancer patients and survivors: A scoping review
Authors: Abedin Khadijah , Lean Qi Ying , Wheelwright Sally 
Published: July 2024

AbstractAimColorectal cancer (CRC) patients need CRC‐specific dietary guidance, but often lack access to adequate nutritional information and support. This scoping review identified study interventions, online resources, which have been produced to support nutritional care self‐management for CRC patients from diagnosis, through treatment and into survivorship and guidelines to underpin these.MethodsThe review was carried out in accordance with the JBI method for Scoping Reviews. Study interventions, online resources that support the self‐management of nutrition and diet in CRC patients were eligible for inclusion, along with CRC‐specific guidelines. Searches up to February 2023, were carried out via MEDLINE, CINAHL, PsycInfo, Embase, and Web of Science for published literature and ProQuest Dissertations, Theses Global, TRIP Medical Database, and Google search engines for grey literature. Two reviewers independently screened titles and abstracts, and relevant full texts for inclusion. Data were analysed descriptively.ResultsEight study interventions, 74 online resources and three guidelines specifically aimed at CRC patients were included in the review. Study interventions were heterogenous with respect to duration, whether it was personalized, who supported delivery and which guidelines underpinned the intervention. Three study interventions resulted in improved quality of life and one lengthened survival. A total of 36 (48.6%) online resources were produced by UK charity organizations. Most of the included information was for patients after completing treatment. Specific advice for patients with a stoma was lacking. Some of the online resources provided conflicting advice. The three guidelines explained how dietary adjustments can help address symptoms related to cancer or treatment and two provided more specific guidance on making dietary changes, with specific examples of how to tailor dietary advice to patient needs.ConclusionThis scoping review of study interventions, online resources, and guidelines highlighted the need for reliable, detailed, and personalized information to help CRC patients to self‐manage their nutritional care.