bluuebunny/crossref_metadata_2025_split huggingface dataset:
Biobased polymer nanocomposites prepared by in situ polymerization: comparison between carbon and mineral nanofillers
Authors: Paszkiewicz Sandra , Walkowiak Konrad , Barczewski Mateusz 
Published: July 2024

AbstractTwo series based on poly(propylene 2,5-furandicarboxylate)-block-poly(tetramethylene oxide) (PPF-b-F-PTMO) containing carbon and mineral nanofillers that differ in shape (1D and 2D) were synthesized via in situ polymerization. The influence of the addition of the 1D-type nanoparticle, i.e., carbon nanofibers (CNFs) and halloysite nanotubes (HNTs), and the so-called 2D-type, i.e., graphene nanoplatelets (GNPs) and organoclay (C20A), on the properties of a biobased block copolymer was analyzed. The dispersion of nanoadditives in the nanocomposites was determined using a scanning electron microscope (SEM). The thermal properties were studied employing differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA). The introduction of nanoparticles increased the crystallinity (Xc) and the mean values of tensile modulus (E) of the bionanocomposites. In turn, one observed that the decrease in the limited viscosity number (LVN) was visible along with incorporating nanoadditives. The synthesized polymer bionanocomposites reveal the mechanical properties of elastomers during mechanical testing. Moreover, the good processability of the obtained materials by injection molding combined with the comprehensive ability to change mechanical and thermal properties of PPF-b-F-PTMO by tailoring the type and content of the nanofillers can indicate their possible applications in packaging, automotive, sports, construction, and many other industries.
Migration and Mental Health in Two Contemporary Memoirs
Authors: Englund Lena 
Published: July 2024

AbstractThis article examines two autobiographical texts that address the relationship between migration and struggles with mental health: Karla Cornejo Villavicencio’s The Undocumented Americans (2021) and Dina Nayeri’s The Ungrateful Refugee: What Immigrants Never Tell You (2020). Both memoirs help bring mental health issues to light in situations of precarity, and the texts indicate that it is not just the experience of physical dislocation that may cause or exacerbate struggles with mental health, but the disconnect from other people, from citizenship, and the nation itself. Nayeri and Cornejo Villavicencio do not focus on narratives of recovery or healing but provide space for the experiences of other undocumented migrants trying to navigate the European asylum system or difficulties in obtaining American citizenship. The article argues that the two authors use their experiences of migration and mental illness for greater advocacy purposes with regard to human rights. The struggles with mental health present in the two memoirs intertwine with the treatment of undocumented migrants as described by the two authors, going beyond the personal experience of mental health, or illness, connecting it with migration practices and policies in the United States and Europe.
Transfer factors of 238U, 232Th, 40K, 210Pb to crops and radiation impact assessment in semi-arid environment
Authors: Dirican A. , Dikmen H. , Şahin M. , Gülay Y. , Özkök Y. Ö. , Kaya N. , Vural M. 
Published: July 2024

AbstractResearch on the safety of staple agricultural food products has always been one of humanity’s priorities and provides input for dose assessment models. Within this important priority, activity concentrations, transfer factors, and radiological effects of 238U, 232Th, 210Pb, and 40K were studied for selected crops in a village close to the NORM area, located in Central Anatolia region of Turkey. The RESRAD-onsite code has been used to assess the total dose rate. The simulation of the risk analysis covered 80 years. The maximum total dose of 0.5 mSv y−1 was obtained at t = 30 years.
Effect of Jardiance on glucose uptake into astrocytomas
Authors: Ghezzi Chiara , Ellingson Benjamin M. , Lai Albert , Liu Jie , Barrio Jorge R. , Wright Ernest M. 
Published: July 2024

Abstract
Purpose
SGLT2, the sodium glucose cotransporter two, is expressed in human pancreatic, prostate and brain tumors, and in a mouse cancer model SGLT2 inhibitors reduce tumor glucose uptake and growth. In this study we have measured the effect of a specific SGLT2 inhibitor, Jardiance® (Empagliflozin), on glucose uptake into astrocytomas in patients.

Methods
We have used a specific SGLT glucose tracer, α-methyl-4-[18F]fluoro-4-deoxy-α-D-glucopyranoside (Me4FDG), and Positron Emission Tomography (PET) to measure glucose uptake. Four of five patients enrolled had WHO grade IV glioblastomas, and one had a low grade WHO Grade II astrocytoma. Two dynamic brain PET scans were conducted on each patient, one before and one after treatment with a single oral dose of Jardiance, a specific SGLT2 inhibitor. As a control, we also determined the effect of oral Jardiance on renal SGLT2 activity.

Results
In all five patients an oral dose (25 or 100 mg) of Jardiance reduced Me4FDG tumor accumulation, highly significant inhibition in four, and inhibited SGLT2 activity in the kidney.

Conclusions
These initial experiments show that SGLT2 is a functional glucose transporter in astocytomas, and Jardiance inhibited glucose uptake, a drug approved by the FDA to treat type 2 diabetes mellitus (T2DM), heart failure, and renal failure. We suggest that clinical trials be initiated to determine whether Jardiance reduces astrocytoma growth in patients.
Efficacy and safety of tirzepatide versus placebo in overweight or obese adults without diabetes: a systematic review and meta-analysis of randomized controlled trials
Authors: Liu Ligang , Shi Hekai , Xie Merilyn , Sun Yuxiao , Nahata Milap C. 
Published: July 2024

Abstract
Background
Tirzepatide was approved to treat type 2 diabetes and obesity, but its efficacy and safety in patients without diabetes has not been investigated.

Aim
This meta-analysis aimed to evaluate the efficacy and safety of tirzepatide compared to placebo in ﻿overweight or obese patients without diabetes.

Method
PubMed, Embase and Cochrane were searched on January 18, 2024. Randomized controlled trials (RCTs) that used tirzepatide in ﻿overweight or obese adults without diabetes were included. Efficacy outcomes included the proportion of participants achieving weight loss targets, changes in body weight (%), body mass index (BMI), waist circumference (WC), and blood pressure (BP). Safety outcomes were commonly reported adverse events. Standardized mean differences (SMD) or odds ratios (OR) with 95% confidence intervals (CIs) were used for continuous and dichotomous outcomes, respectively.

Results
Three RCTs with 3901 participants were included. Tirzepatide was associated with increased proportion of participants achieving weight loss targets, reduced body weight (SMD − 1.61, 95% CI − 2.20 to − 1.02), BMI (SMD − 2.13, 95% CI − 3.08 to − 1.18), WC (SMD − 0.91, 95% CI − 1.14 to − 0.69), and BP versus placebo. However, the risk of adverse events such as nausea (OR 4.26, 95% CI 2.60 to 3.81), vomiting (OR 8.35, 95% CI 5.19 to 13.45), and diarrhea (OR 3.57, 95% CI 2.80 to 4.57) was significantly higher for tirzepatide versus placebo.

Conclusion
Tirzepatide significantly reduced weight and improved metabolic markers among ﻿overweight or obese without diabetes. However, increased adverse events highlights the need for benefits versus risks assessment before initiation and continuous monitoring.
Mg2+ limitation leads to a decrease in chlorophyll, resulting in an unbalanced photosynthetic apparatus in the cyanobacterium Synechocytis sp. PCC6803
Authors: Pohland Anne-Christin , Bernát Gábor , Geimer Stefan , Schneider Dirk 
Published: July 2024

AbstractMg2+, the most abundant divalent cation in living cells, plays a pivotal role in numerous enzymatic reactions and is of particular importance for organisms performing oxygenic photosynthesis. Its significance extends beyond serving as the central ion of the chlorophyll molecule, as it also acts as a counterion during the light reaction to balance the proton gradient across the thylakoid membranes. In this study, we investigated the effects of Mg2+ limitation on the physiology of the well-known model microorganism Synechocystis sp. PCC6803. Our findings reveal that Mg2+ deficiency triggers both morphological and functional changes. As seen in other oxygenic photosynthetic organisms, Mg2+ deficiency led to a decrease in cellular chlorophyll concentration. Moreover, the PSI-to-PSII ratio decreased, impacting the photosynthetic efficiency of the cell. In line with this, Mg2+ deficiency led to a change in the proton gradient built up across the thylakoid membrane upon illumination.
Determining universality of m-gonal forms with first five coefficients
Authors: Park Dayoon 
Published: July 2024

AbstractWe classify the $$(a_1,a_2,a_3,a_4,a_5)$$

(

a
1

,

a
2

,

a
3

,

a
4

,

a
5

)

for which the universality of an m-gonal form $$F_m({\textbf{x}})$$

F
m

(
x
)

whose first five coefficients are $$(a_1,a_2,a_3,a_4,a_5)$$

(

a
1

,

a
2

,

a
3

,

a
4

,

a
5

)

is characterized as the representabilitiy of positive integers up to $$m-4$$

m
-
4

and discuss some applications.
Anthropocene Literacy for Science Education
Authors: Lee Seul-gi , Park Buhm Soon 
Published: July 2024

AbstractNo scientific concept in the twenty-first century has garnered more attention from scholars outside the scientific community than the Anthropocene. Despite the official rejection by the geological community in March 2024 of the proposal for an Anthropocene Epoch as a formal unit of the Geological Time Scale, it is expected to remain an invaluable descriptor of human impact on Earth. It is also undeniable that it will continue to inspire vigorous studies not only in geology, ecology, and Earth system science but also in the humanities, social sciences, and the arts. How, then, can the Anthropocene be effectively taught in science classrooms? This paper seeks to underscore the value of teaching this novel yet controversial concept to STEM students and proposes an educational curriculum that addresses both scientific content and social issues. The primary pedagogical object is to foster what we call “Anthropocene literacy,” which comprises three key components: understanding the nature of science through the lens of the Anthropocene, embracing a multidisciplinary approach, and gaining insight into the impact of human activities on the Earth. These components serve as the cornerstone of our proposed educational framework, which aims to equip students with the knowledge and critical thinking skills necessary to comprehend the complexities of the Anthropocene and its implications for our planet.
Ten year citation prediction model for systematic reviews using early years citation data
Authors: Marques-Cruz Manuel , Dias Daniel Martinho , Fonseca João A. , Sousa-Pinto Bernardo 
Published: July 2024

AbstractCitation counts are frequently used for assessing the scientific impact of articles. Current approaches for forecasting future citations counts have important limitations. This study aims to analyse and predict the trajectories of citation counts of systematic reviews (SR) based on their citation profiles in the previous years and predict quantiles of future citation counts. We included all SR published between 2010 and 2012 in medical journals indexed in the Web of Science. A longitudinal k-means (KML) clustering approach was applied to identify trajectories of citations counts 10 years after publication, according to the yearly citation count, the proportion of all cites attained in a specific year and the annual variation in citation counts. Finally, we built multinomial logistic regression models aiming to predict in what tercile or quartile of citation counts a SR would be 10 years after publication. Using clustering approaches, we obtained 24 groups of SR. Two groups (7.9% of the articles) had an average of > 200 citations, while two other groups (10.4% of the articles) presented an average of < 10 citations. The model predicting terciles of citation counts attained an accuracy of 72.8% (95%CI = 71.1–74.3%) and a kappa coefficient of 0.59 (95%CI = 0.57–0.62). Prediction of citation quartiles (combining the second and third quartiles into a single group) attained a accuracy of 76.2% (95%CI = 74.7–77.8%) and a kappa coefficient of 0.62 (95%CI = 0.59–0.64). This study provides an approach for predicting of future citations of SR based exclusively on citation counts from the previous years, with the models developed displaying an encouraging accuracy and agreement.
Roman Witold Ingarden’s discussions on artistic style: A contribution
Authors: Garlej Beata 
Published: July 2024

AbstractThe present article attempts to reconstruct Polish philosopher and aesthetician Roman Witold Ingarden’s views concerning his understanding of the concept of artistic style. Starting from the hypotheses provided by the content of the outline of his ultimately unwritten work, Poetics, I have chosen selected threads of the discussions held by Ingarden in Lviv before the war, supplemented by the content of the phenomenologist’s lectures from the 1960s, as essential substantive background. Analyzing the material indicated, I demonstrate that it is appropriate for Ingarden’s understanding of artistic style to correlate this concept with the category of aesthetic concretization. Consequently, I draw a conclusion as to the primary role of some aspects of a literary work – appearances, which allow us to inquire into the properties of artistic style practically as a result of their function of decorativeness and polyphony. A condensed comparative analysis of the two functions, as related to excerpts from Gustave Flaubert’s Madame Bovary and Stanisław Ignacy Witkiewicz’s Insatiability, concludes the account of Ingarden’s conception of artistic style, which turns out to be a unique aphenomenal phenomenon.
Peer relationships and study wellbeing: upper secondary students’ experiences
Authors: Tikkanen Lotta , Anttila Henrika , Ulmanen Sanna , Pyhältö Kirsi 
Published: July 2024

AbstractThe role of peer relationships in a student’s study wellbeing has been emphasised in research. However, the development of functional relationships with peers in educational settings cannot be taken for granted. In this study, we aimed to understand the variations in upper secondary school students’ experiences of peer relationships in terms of sense of relatedness, cognitive and affective empathy skills and peer support for studying, and whether variation in these regards are related to study wellbeing. Two hundred and eighty Finnish upper secondary education students participated in the study. The data were analysed using latent profile analysis (LPA). Three distinct peer relationship profiles were detected among the students. Most of the students belonged to the functional peer relationship profile, while a minority belonged to either isolated or emotionally unrelated profiles. The students in the latter two profiles had a higher risk of experiencing challenges in study wellbeing in terms of reduced levels of study engagement and higher levels of study burnout symptoms. The findings imply that students in upper secondary education might need different kinds of support in building functional peer relationships. For example, some of them might benefit from learning empathy skills, while others might need support to meet their need for a sense of relatedness among peers.
Arbuscular mycorrhizal fungi affect early phenological stages of three secondary vegetation species in a temperate forest
Authors: Vázquez-Santos Yasmin , Castillo-Argüero Silvia , Montaño Noé Manuel , Espinosa-García Francisco Javier , Flores-Ortiz César , Martínez-Orea Yuriana 
Published: July 2024

AbstractThe relationship between arbuscular mycorrhizal fungi (AMF) and secondary vegetation (SV) species at early phenological stages is critical for the successful establishment of these plants on disturbance sites in temperate forests. The main objective of this research is to evaluate the effect of AMF colonization on the early phenological stages (germination and early growth) of three shrub species present in the SV of a temperate forest in central Mexico. We collected soil from different sites in theAbies religiosaforest in central Mexico. We collected seeds ofAcaena elongata,Ageratina glabrata, andSolanum pubigerum. We used a controlled experimental design with pasteurized soil (-AMF treatments) and unpasteurized soil (+ AMF treatments). We monitored germination percentage, growth (shoot and root weight and total biomass), AMF root colonization, and the mycorrhizal response index (MRI) for each plant species. All three species tested benefited by AMF, showing higher germination rates. Shoot and root weight and total biomass were significantly higher in the + AMF treatment.Solanum pubigerumshowed greater stem length andAgeratina glabratashowed greater root development due to AMF.Ageratina glabrataandAcaena elongatawere the most responsive to AMF as indicated by MRI. This research underscores the critical role of AMF in the early phenological stages of SV and highlights the potential ecological benefits of AMF in supporting plant germination and plant growth. These results suggest that AMF enhance germination and early growth of secondary vegetation species, which can be considered in management plans for forest ecosystems.
Determination of persistent organic pollutants in urban and peri-urban wastewater sludge: environmental and carcinogenic human risk assessment in the case of land application
Authors: Bruzzoniti Maria Concetta , Tumiatti Vander , Quazzo Armando , Beldean-Galea Mihail Simion , Del Bubba Massimo , Rivoira Luca 
Published: July 2024

AbstractThe management of digested sludge derived from treatment water plants is a problem worldwide due to the possible transfer of contamination from sludge to amended soil and, in turn, to humans. Within this work, through a chemometric experimental design, a robust GC–MS method for the simultaneous determination of two classes of micropollutants of concern (polycyclic aromatic hydrocarbons—PAHs—and polychlorinated biphenyls—PCBs—including dioxin-like compounds) was developed using microwave-assisted extraction (MAE). The method, which showed interesting greenness features in compliance with the 12 principles of Green Chemistry, allowed PCB and PAH extraction with recoveries higher than 75% (RSD < 14%) with method detection limits between 4.6 and 11.5 µg kg−1 (PAHs) and between 6.9 and 13.7 µg kg−1 (PCBs), without preconcentration. The matrix effect was below 20%. The validated protocol allowed the characterization of two digested sludges sampled in an urban and a peri-urban district, representative models of two scenarios of different anthropic impacts. This study highlighted higher contamination for the sludge derived from the urban area, accounted for by the 4-ring PAHs. In addition, since carcinogenic PAHs were detected, the environmental risk (by mean of the comparison of predicted vs predicted no-effect concentrations) and the carcinogenic human risk from dermal contact (through the calculation of the adsorbed lifetime average daily dose) were assessed in the case of soils amended with the sludges considered, pointing out that the measured concentrations do not pose a risk.
The effect of spatial lag on modeling geomatic covariates using analysis of variance
Authors: Aquiles E. Darghan C. , Darlley S. Taborda L. , Nair J. González S. , Carlos A. Rivera M. , Jesús E. Ospina N. 
Published: July 2024

AbstractIn recent years, statistical methods have been developed that include spatial considerations, for example, those that incorporate data with georeferencing. The descriptive part of geographical information systems currently provides many visualization and analysis tools; however, in terms of analysis, these systems are still quite limited, therefore, ignorance of these limitations may result in data with spatial effects being treated with conventional statistical methods for non-spatial use, which can certainly invalidate the excellent work of data capture with advanced tools such as those that are used daily in the geomatic context. This prompted the current document, drawing attention to how geomatic information analyzed with statistical methods that imply independence in modeled observations can be invalid. The Moran index is compared with a proposal for a spatial lag coefficient in the context of experimental design so that users of variance analysis do not apply this well-known procedure in a ritualistic way, perhaps revising some assumptions and perhaps ignoring more important ones. The distortion of the p value generated from the analysis of variance is clear in the presence of spatial dependence. In this case, it is associated with the lag or spatial overlap. The methodology is easy to apply in other designs with the development of the design matrix, its reparameterization and the choice of the respective weight matrix. This may cause users to reconsider the traditional method of analysis and incorporate some appropriate analysis methodology to address spatial effects present in data or in outputs from the modeling process.
Reindeer prey mobility and seasonal hunting strategies in the late Gravettian mammoth steppe
Authors: Pryor A. J. E. , Nesnídalová T. , Šída P. , Lengyel G. , Standish C. D. , Milton J. A. , Cooper M. J. , Hambach B. , Crowley J. , Wilczyński J. 
Published: July 2024

AbstractReindeer are part of the faunal suite that dominated central Europe during the last glacial cycle. Their importance to Late Gravettian hunters as prey and a source of raw materials (hide, bone, antler) is well attested, however the context of Late Gravettian reindeer predation is lesser understood. This paper presents an investigation of human and reindeer predator-prey interactions at the Late Gravettian kill-butchery site of Lubná VI, Czech Republic. We reconstruct seasonal mobility (87Sr/86Sr, δ18O), diet (δ13C, δ15N) and season of death (dental cementum) of up to nine reindeer prey, to inform on the strategic choices made by Late Gravettian hunters. Results indicate that most hunted reindeer lived year-round in the foothills of the Bohemian-Moravian highlands near where Lubná is located, at altitudes between ~ 200–450 m above present sea level, while a smaller number showed evidence of seasonal migration between this area and the open plains of the Elbe river corridor (Bohemian Cretaceous basin). No evidence for long distance migration of reindeer was detected, indicating that productive local environments were supporting reindeer herds within a single annual territory. Meanwhile, areas higher than ~ 450 m above present sea level were avoided entirely by all analysed individuals, consistent with these areas being topographic barriers to movement due to climate severity. We conclude that hunters visited Lubná as part of a logistically-organised subsistence strategy, deliberately targeting reindeer in late autumn when fat supplies, hides and antler are in prime condition knowing that they would reliably encounter their prey at this location.