bluuebunny/crossref_metadata_2025_split huggingface dataset:
Organ Donation: Willingness, Attitude, and Knowledge among General Population of Western India – A Cross-sectional Study
Authors: Prajapati Devarsh , Verma Mamtarani , Balusamy Divakar 
Published: June 2024

Background:
The issue of organ donation is complex and multifactorial involving ethical, legal, medical, organizational, and societal factors. There is a wide gap between the required number of donations and actual donations in India. There is a need to identify the reasons for this wide gap from the community perspective.

Methods:
A cross-sectional study was done among relatives of patients attending the outpatient department at a tertiary care center. Data were collected using a pre-designed semi-structured questionnaire. For the assessment of knowledge, relevant questions were asked. Attitude toward organ donation was assessed using 22 items on a 5-point Likert scale. Data were entered into Excel sheet and analyzed using SPSS software. Average knowledge, attitude, and practice scores were calculated and compared with religion, gender, and other sociodemographic variables. A Chi-square test of association was applied between sociodemographic variables and their willingness to sign the donor card. P <0.05 was considered statistically significant. Their suggestions for improving organ donation practices were also documented.

Results:
The average knowledge score among participants was 8.06. Good, average, and poor attitude toward organ donation were found among 3 (0.77%), 339 (87.37%), and 46 (11.86%) participants, respectively. Good, average, and poor practice toward organ donation were observed among 1 (0.26%), 65 (16.75%), and 322 (82.98%) participants, respectively.

Discussion:
When deciding whom to donate their organs, 156 (40.21%) said that the health status of the recipient and his/her chances of survival will be the most important factor. Age and poor health status were the major barriers toward organ donation among participants. Still, many participant’s motivation toward organ donation was that they want to help others and 190 (49.0%) participants were willing to be part of awareness group and promote organ donation activity in the society. Solving their barriers/reasons for refusing organ donation may help to improve organ donation in the society.

Conclusion:
Knowledge has an impact on changing person’s attitude and practice; even our study has shown significant results of association between knowledge and attitude, knowledge and practice as well as attitude to their practice toward organ donation. Age and poor health status were the major barriers toward organ donation among participants.
Second-degree Burns Treated with Homeopathic Medicine Cantharis
Authors: Maheswari M. S. Uma , Maalolan S. , Sisir P. R. , Mahadevi A. L. 
Published: June 2024

Abstract
Burn injuries are among the most fascinating and difficult cases that arise in everyday clinical practice. We present the case of a 10-year-old kid who sustained an unintentional second-degree partial-thickness burn injury. The youngster experienced discomfort and burning at the impact site, in addition to limited movement. Cantharis 200 was given to him internally; glycerine lotion was applied externally; and a dilution of Cantharis 200 was used for dressing. The patient showed notable improvement in just 6 weeks, as demonstrated by the Modified Naranjo Criteria for Homoeopathy (MONARCH) score of 9, which indicated relevance in treatment outcome.
Assessing the Role of Salivary Alpha-Amylase in Dental Caries in Children aged 6–9 Years – A Cross-sectional Study
Authors: Surana Monika , Shah Vandana , Acharya Dhruval S. 
Published: June 2024

Abstract

Introduction:
Salivary alpha-amylase is an enzymatic powerhouse, breaking down starch in food and whisking it away from the oral cavity. Its presence in the acquired enamel pellicle hints at involvement in the adhesion of α-amylase-binding bacteria. This study delves into the impact of salivary alpha-amylase in children with varying caries statuses, aiming to understand its correlation with the severity of dental caries.

Aims:
The aim of this study was to determine the relation between salivary alpha-amylase levels in children with dental caries.

Material and Methods:
Ninety children in the age range from 6 to 9 years were enrolled. The caries status is assessed using the decayed, missing, and filled teeth index. Each participant provided unstimulated whole saliva samples, which were centrifuged at 5000 rpm for 5 min to eliminate debris. Alpha-amylase concentration was estimated using Auto-analyzer (ERBA EM-200).

Results:
The mean values of salivary α-amylase were 4.2% higher in girls than in boys. The salivary α-amylase levels were found to increase slightly from the control group to the caries group though statistically nonsignificant.

Conclusions:
Although salivary α-amylase levels not showed a statistical significance correlation to dental caries, it does throw a light on the biochemical aspect of salivary alpha-amylase correlated to other factors, influencing dental caries such as gender, dietary preferences, adverse oral habits, and hormonal influence.
A Study on Subjective Aerodynamic Measurement among the Gujarati-speaking Healthy Adults in West Cost India
Authors: Sheena  , Thomar Manasvi , Vishwakarma Arjun , Sinha Parthib 
Published: June 2024

Abstract

Introduction:
The adequate respiratory functions are important for lifesaving like breathing, and communications such as vocalization in speech productions, and additionally, it supports for airway protective mechanisms by strengthening the protective cough. The maximum phonation duration (MPD) and maximum utterance of /s/, /Z/ and its ratio are the important aerodynamic parameters that indicate the respiratory functions and its impact on breathing, vocalization as well as protective mechanism.

Aim:
The aim of this study was to review and contrast the results of subjective aerodynamic assessments of maximum phonation time/duration and S/Z ratio in seconds among Gujarati-speaking healthy adult populations.

Objective:
The current study attempted to construct the normalization of MPD and S/Z Ratio for both males and females.

Results:
Mean MPD for males was greater than females, whereas s/z ratio for males and females was around 0.97 s.

Conclusion:
By developing normative statistics among Gujarati-speaking adult populations for both genders, it will be possible to utilize them as a reference for clinical diagnosis and for an intervention program for people with respiratory issues and other voice diseases.
Necrotizing Fasciitis of the External Auditory Canal: A Rare Complication of Chronic Suppurative Otitis Media
Authors: Adamu Auwal , Kirfi Abdullahi Musa , Gwalabe Sabiu Abdu , Fufore Mohammed Bello , Mahmud Ahmad 
Published: June 2024

Abstract
Complications of chronic suppurative otitis media (CSOM) are still prevalent in developing countries, with some of the patients presenting with rare complications. CSOM can affect the external auditory canal (EAC) in different ways, and the most common affectation is EAC stenosis or atresia. Manifesting with necrotizing fasciitis of the EAC is extremely rare. Only a few cases have been reported in the literature, and none was from otitis media. In this article, we reported a rare case of necrotizing fasciitis of the EAC from CSOM in a malnourished child.
Effect of 8-week Abdominal Core Endurance Training on Shoulder Pain and Function in Patients with Rotator Cuff Tendinopathy
Authors: Shetty Mamta , Laxman Aditi , Bhadra Nirali 
Published: June 2024

Abstract

Background:
The focus of this study is to report the influence of core muscle endurance training on shoulder pain and function.

Materials and Methods:
Participants (n = 60) were randomly divided into two groups: group A (core rehabilitation group) and Group B (conventional group). The participants were assessed for shoulder pain using the Numerical Rating Scale, shoulder range of motion using a universal goniometer, Shoulder Pain and Disability Index (SPADI), and core muscle strength using pressure biofeedback pre- and postintervention.

Results:
There was a significant reduction in shoulder pain in both the groups (P = 0.00), with mean pain scores of 37.67 years in Group A and 39 years in Group B. There was a significant increase in core muscle endurance in Group A (P = 0.00) as compared to Group B. The shoulder function as measured by SPADI score improved significantly in Group A (P = 0.00) as compared to Group B, with mean scores of 20.40 in Group A and 31.90 in Group B.

Conclusion:
Findings from the present study report that the addition of abdominal core muscle endurance training in patients with rotator cuff tendinopathy was effective as compared to conventional exercises only for improving the shoulder function.
Knowledge, Attitude, and Practice among Pediatric Dentists Regarding Oral Manifestations of COVID-19 in Children: An Electronic Cross-sectional Survey
Authors: Shah Arpita , Dave Bhavna , Bargale Seema , Deshpande Anshula , Poonacha K. S. , Kariya Pratik 
Published: June 2024

Abstract

Introduction:
Pediatric dentists play a role in the prevention of the communicable diseases such as COVID-19 and in the identification and referral of those children. There are concerns about the identification, referral, diagnosis, and treatment of oral manifestations of COVID-19 in children.

Aim:
To assess the knowledge, attitude, and practice (KAP) among pediatric dentists regarding oral manifestations of COVID-19 in children.

Materials and Methods:
This questionnaire-based cross-sectional survey included 255 registered pediatric dentists at Indian Society of Pedodontics and Preventive Dentistry. They were E-mailed an E-questionnaire with the help of Google Forms portal including informed consent and 16 formulated questions assessing the KAP among pediatric dentists regarding oral manifestations of COVID-19 in children. Incomplete forms were not accepted. The response was awaited for a period of 3 months. The collected data were subjected to descriptive and Chi-square analysis.

Results:
Sixty-three percent of the population had knowledge about all the oral manifestations of COVID-19 seen in children. Sixty percent were unsure about scheduling the next dental appointment for such patients. 48.3% of pediatric dentists could not prescribe medications for oral manifestations of COVID-19.

Conclusion:
Pediatric dentist could identify and diagnose the oral manifestations of COVID-19 and its associated complications however were unsure of treatment modalities as there is limited evidence for definitive treatment regarding the same. Clinical protocols concerning treatment for oral manifestations due to COVID-19 should be well established and practiced.
Role of Evidence based Management of Ayurveda Medicines in Insomnia: A Critical Review
Authors: Irshad Nazia , Singh Naimish Raj , Varsakiya Jitendra Kumar , Kumari Pooja , Kathad Divyarani 
Published: June 2024

Abstract
A person with insomnia has trouble falling asleep or gets insufficient, poor-quality sleep. They might experience frequent nighttime awakenings with difficulty going back asleep and early morning wakefulness. It is common in older adults, females, students, and people with medical illness. The aim is to analyze and review the published clinical studies conducted on insomnia to assess the effectiveness of Ayurvedic remedies for the management of insomnia. For this review, the literature has been searched using databases such as Medline, PubMed, NLM, Ayush Research Portal, and many others. All randomized controlled trials involving individuals with insomnia, utilizing Ayurvedic herbs either alone or in combination and Panchakarma procedures (processes of detoxifying and purifying the body) with an exposure period of ≥7 days, and with the primary outcome being the improvement in sleep quality, were included. This review includes 16 clinical trials, among them Mansyadi Kwath (decoction made up of Jatamamsi (Nardostachys jatamansi DC), Ashwagandha (Withania somnifera Linn.) and Parsik Yvani (Hyoscyamus niger Linn.), Aswagandha (W. somnifera Linn.), Jatamansi (N. jatamansi DC), Tagar (Valeriana wallichii DC.), Brahmi (Bacopa monnieri Linn.), Gud Pippali Churna (powder of jaggery and root of Piper longum Linn.), Jatipatri Ksheerpaka (milk decoction of Myristica fragrans Houtt.), Insomrid tablet (tablet made up of 5 drugs named Jatamamsi, Ashwagandha, Parsik Yvani (H. niger Linn.), Tagar (Valeriana wallichii DC.), and Sarpagandha (Rauwolfia serpentina Benth.) and Shirodhara (~slowly and steadily dripping medicated liquids on the forehead) are found effective in the treatments of insomnia according to these studies. This research serves as secondary data for further studies and the medication are described here have the ability to manage insomnia with very minimal or no side effects. These drugs are also cost-effective and nonaddictive.
Burnout in Physiotherapy Students of Ahmedabad: An Observational Study
Authors: Jain Anjali , Sheth Megha 
Published: June 2024

Abstract

Background:
Burnout is a syndrome recorded as resulting from chronic workplace burdens that are not successfully managed. Physiotherapy students report high levels of daily hassles, workload, and lack of manageability and understanding throughout their university years. Burnout has been noted in medical students and physiotherapy teachers. Therefore, there is a need to study burnout in physiotherapy students.

Aims:
The aim of the study was to discover burnout in physiotherapy students using the Oldenberg burnout inventory (OLBI).

Setting and Design:
A survey of physiotherapy students of Ahmedabad was done through Google Forms.

Materials and Methods:
Data were obtained from 300 students using convenience sampling. Participants’ age, gender, and year of study were asked, and burnout was assessed using OLBI.

Statistical Analysis:
Descriptive analysis was done, and the Chi-square test was applied between burnout and gender, year of study, and physical activity.

Results:
Three hundred students with a mean age of (20.95 ± 2.05) years participated in the study, including 234 (78%) females and 66 (22%) males. A total of 239 (79.67%) undergraduate students and 61 (20.33%) postgraduate students participated in the study. The mean OLBI score is (38.71 ± 4.95). The mean exhaustion score is (19.14 ± 2.77) and mean disengagement score is (19.57 ± 2.73). The Chi-square analysis showed no significant impact of participant gender (χ2 (1) = 36.211, P = 0.167) and year of study (χ2 (1) = 162.060, P = 0.732) but a significant impact of physical activity (χ2 (1) = 44.977, P = 0.030) on the burnout in the sample.

Conclusion:
There is medium burnout present in physiotherapy students of Ahmedabad.
A Newly Formulated Vinyl Polysiloxane Impression Material with Improved Mechanical Properties
Authors: Ling Long , Lai Theresa , Malyala Raj 
Published: June 2024

Abstract

Aim:
To evaluate the mechanical properties of a newly formulated vinyl polysiloxane (VPS) impression material.

Materials and Methods:
Experimental, Capture (S&C Polymer), Express, Imprint 3 and Imprint 4 (3M ESPE), Start VPS (Danville), Honigum (DMG), Virtual (Ivoclar Vivadent), Elite HD+ (Zhermack) were evaluated for tear strength, tensile strength, and elongation at break. Un-nicked specimens with a 90° angle on one side (type C) for tear strength were prepared and tested according to ASTM-D624. Dumbbell-shaped specimens (type 1) for tensile strength and elongation at break were prepared and tested according to ISO 37. All tests were carried out at 500 mm/min on a Shimadzu (AGS-X-10 KN-table top) tester. A one-way analysis of variance (ANOVA) was used to analyze the data.

Results:
Experimental material showed significantly higher or higher tear strength and elongation at break compared to other impression materials for both light body (LB) and heavy body (HB). For tensile strength, Experimental is similar to most impression materials; however, significantly lower than Imprint 3 and Start VPS for LB. This parameter for HB is higher or significantly higher than other impression materials except Start VPS. Tear strength and tensile strength were not correlated for LB but have a weak or moderate correlation for HB. Elongation at break is inversely proportional to tensile strength moderately for LB; however, there is no or very weak relation for HB.

Conclusions:
Experimental VPS impression material demonstrated a significantly higher tear strength and adequate tensile strength with higher elongation compared to other commercially available VPS impression materials. Adequate mechanical properties can provide accurate impressions for successful clinical fabrication of restorations. Experimental VPS impression material is suitable for use in dental impressions for fabrication of restorations.
Effect of Different Electroconductive Root Canal Irrigations on the Accuracy of Different Apex Locators: An In Vitro Comparative Study
Authors: Yahya Eman M. , Alchalabi Ashraf S. , Alkhalidi Emad Farhan 
Published: June 2024

Abstract

Aim:
An accurate working length (WL) estimation is fundamental to a successful endodontic therapy. The objective of this comparative in vitro research was to investigate the performance of iPex II and the Root ZX Mini electronic apex locators (EALs) in measuring root canal WL with different irrigant solutions and their relation to the electrical conductivity of irrigation solutions.

Materials and Methods:
Seventy sound permanent lower premolar teeth, each with a single root and developed apices, were used. Under an X15 stereomicroscope, the real working length was determined with the aid of a #10 file. After that, teeth were placed into an alginate model, and the iPex II and Root ZX Mini were used for the detection of electronic working length with various irrigants. Seventy teeth were randomly distributed into seven groups, 10 per each group (group I: dry canal; group II: distilled water; group III: ozonated water; group IV: 5% sodium hypochlorite (NaOCl); group V: 2% chlorhexidine, group VI: 17% ethylenediaminetetraacetic acid (EDTA) solution, and group VII: 17% EDTA gel). The difference in WL was calculated by deducting real working length from its electronic working length. The study also evaluates the electrical conductivity of the seven endodontic irrigant solutions. The two-way analysis of variance (ANOVA) test was used for statistical analysis.

Results:
Statistically, neither both types of EALs (P = 0.088) nor various irrigating solutions with varying electrical conductivities (P = 0.099) significantly affect the accuracy of EL estimation.

Conclusions:
There were no significant differences between the accuracy of the Root ZX Mini and the iPex II. The accuracy of both apex locators is unaffected in the presence of various irrigation solutions with varying electrical conductivities in this research.
Role of microRNAs in Diabetes-Associated Periodontitis: A Scoping Review
Authors: Agnihotri Rupali , Gaur Sumit , Bhat Subraya Giliyar 
Published: June 2024

Abstract

Aim:
Diabetes mellitus (DM), a metabolic disorder, exhibits a bidirectional relationship with periodontitis (PD), and recently, microRNAs (miRNAs) were associated with their progression. This review aims to assess the role of miRNAs in the pathogenesis of DM-associated PD and their plausible application as a biomarker for PD in individuals with DM.

Materials and Methods:
The search conducted until September 2023 on Medline (Pubmed), Scopus, Embase, and Web of Science using the keywords “microRNA,” “miRNA,” or “miR,” combined with “Diabetes” and “PD” yielded 100 articles. Only research focusing on the role of miRNAs in the pathogenesis of DM-associated PD and their potential application as biomarkers for both conditions were included. Finally, 14 studies were assessed for any bias, and the collected data included study design, sample size, participant groups, age, sample obtained, PD severity, miRNAs examined, clinical and biochemical parameters related to DM and PD, and primary outcomes.

Results:

In vivo studies indicated altered expression of miRNAs-146a, -146b, -155, -200b, -203, and -223, specifically in the comorbid subjects with both conditions. Animal, ex vivo, and in vitro studies demonstrated altered expression of miRNAs-126, -147, -31, -25-3p, -508-3p, -214, 124-3p, -221, -222, and the SIRT6-miR-216/217 axis. These miRNAs impact innate and adaptive immune mechanisms, oxidative stress, hyperglycemia, and insulin sensitivity, thereby promoting periodontal destruction in DM. miRNA-146a emerges as a reliable biomarker of PD in DM, whereas miRNA-155 is a consistent predictor of PD in subjects without DM.

Conclusions:
miRNAs exert influence on immuno-inflammation in DM-associated PD. Although they can be biomarkers of PD and DM, their clinical utility is hindered by the absence of standardized tests to evaluate their sensitivity and specificity. Moreover, there has been limited exploration of the role of miRNAs in DM-associated PD through human studies. Future clinical trials are warranted to address this gap, focusing on standardizing sample collection, miRNA sources, and detection methods. This approach will enable the identification of specific miRNAs for DM-associated PD.
Noncommunicable disease incidence and mortality in Chandigarh Union Territory, 2018–2019: Findings from the Chandigarh Noncommunicable Disease Registry
Authors: Thakur J. S. , Kaur Rajbir , Paika Ronika , Malhotra Pankaj , Bhadada Sanjay Kumar , Kapoor Rakesh , Vijayvergiya Rajesh , Khurana Dheeraj 
Published: June 2024

Context:
The Chandigarh Noncommunicable Disease (NCD) Registry was set up in 2018 to assess the burden of major NCDs and inform the planning of public health and clinical interventions.

Aim:
The aim of the present study was to assess the burden of NCDs in Chandigarh.

Settings and Design:
The cross-sectional study design includes data from government and private facilities, pathology laboratories, birth, and death registrar offices catering to urban and rural Chandigarh.

Subjects and Methods:
It collects data of young diabetes, stroke, acute cardiac events, aplastic anemia, and cancer patients using a structured questionnaire.

Statistical Analysis Used:
The study reports a descriptive analysis of case distribution, done using SPSS version 23. MS Excel 2016 was used to produce graphical illustrations and calculate age-adjusted rates using the world standard population.

Results:
During July 2018–December 2019, 3721 (incident and death) cases were recorded for cancer (n = 2414, 64.9%), acute cardiac events (n = 1034, 27.8%), stroke (n = 231, 6.2%), young diabetes (n = 28, 0.8%), and aplastic anemia (n = 14, 0.4%). The age-adjusted incidence and mortality rates (per 100,000 population) were calculated for cancer (males: 102.6 and 62.0; females: 100.8 and 52.9), acute cardiac events (males: 47.1; females: 21.7 and 28.8), and stroke (males: 7.5 and 8.5; females: 13.1 and 21.8). Study participants were exposed to tobacco and alcohol consumption. Positive family history was reported by 40% of the registered patients.

Conclusions:
An integrated model of the NCD registry is feasible and can yield evidence in low-resource settings for secondary prevention to achieve global targets for reducing risk factors and premature mortality due to NCDs.