bluuebunny/crossref_metadata_2025_split huggingface dataset:
Circumferential Proximal Femoral Allografts in Revision Hip Arthroplasty: Four to 20 Years Follow-Up
Authors: Roos Bruno Dutra , Roos Milton Valdomiro , Camisa Antero 
Published: February 2013

Purpose The purpose of this study was to analyze the clinical and radiographic results of revision of loose total hip replacements, using proximal femoral allografts and a cemented implant. Material and methods We retrospectively reviewed of 28 consecutive patients. Twenty patients were available for study. Each patient was scored using a modified Harris Hip Score. Radiographs were examined for endosteal and periosteal reabsorption, allograft-host union, trochanteric migration, component loosening and heterotrophic calcification. Results The mean pre-operative Harris hip Score was 34 points. At the latest follow-up, the meanscore was 80 points. Nineteen cases (95%) had combined femoral defects and one patient (5%) had a segmental defect, according to the AAOS classification. Allograft resorption was seen in eight (40%) hips. There were 18 cases (90%) of allograft union, one (5%) of partial union and one (5%) of nonunion. There was one case of trochanteric migration (more than 1 cm). All femoral components were radiographically stable. The reconstruction was considered successful in 18 patients (90%). Conclusion The use of proximal femoral allografts in femoral revision of loose total hip replacements has high survival and satisfactory clinical results at an average period of eight years postoperatively.
Differentiated chondrosarcoma, originated in thyroid cartilage of larynx: evaluation and treatment. Clinical case presentation
Authors: Pocius Linas , Čepulis Vytautas 
Published: February 2013

Background. The goal of our clinical case presentation is to introduce evaluation and treatment of rare head and neck tumor, the laryngeal chondrosarcoma (CS). Despite disease origin being properly suspected at the early management of our patient, the final outcomes tend to be just satisfactory because too many cofactors have had a strong influence on the course of disease.
Materials and methods. In this case, we described applied investigations and chosen tactics of treatment to our patient in a chronological manner, some immediate results, but also remote consequences of the management of this disease.
Results. In our opinion, outcome in this patient’s case was predicted not just by the biology of malignancy itself, but also by some specific qualities of the tumor and even misinterpretations of instrumental examination at the moment of making decisions regarding the initial treatment; moreover, some solutions, corrected by the patient himself, maybe played an important role in the clinical course further. We want to point out how achieved results and outcomes could be unpredictable, under influence of near coincidence of fate, and different, in comparison with the cases described in the majority of the literature.
Conclusions. 1. Relatively simple diagnostic with contemporary features, plenty of modern surgical treatment possibilities or even combined therapy in complicated cases – it makes no difficulties for management of typical chondrosarcoma of the larynx, yet sometimes tricky findings when evaluating the disease and an unpredictable or surprising course of treatment and continuation make this rare kind of head and neck malignancies really special. 2. RT neither chemotherapy are recommended therapeutic options, except some rare individual cases. 3. Conservative surgery tends to be adequate if made properly and in time, it obviously ensures long-term remission or cancer-free life.
Flood Risk Assessment: Level of Property Damage and Casualty in Northeastern Mindanao Philippines
Authors: Badiola Richard A. 
Published: February 2013

Flood disaster poses a serious threat to people and property. As society progresses, it constantly modify the environmental landscape which heightens the risk of a disaster. Vital step to disaster reduction should be directed to a comprehensive evaluation of the likelihood of potential losses such as destruction of property and/ or deaths. This study aims to assess the level of risk associated to flood damage and casualty at Community level. The level of risk depends on two interrelated factors: level of hazard and the level of its consequence. A Modified Risk Assessment Framework was utilized to evaluate each of the components of risk. Results significantly matched the geological hazard assessment conducted by local experts. Eleven Villages are high risk of loss of life while eight Villages are high risk of property damage. Restricting physical developments, limiting population expansion, investing on structural measures, boosting the socio-economic condition and strengthening the environmental regulations may help reduce the risk. Keywords - Risk, Vulnerability, Exposure, Hazard, Consequence, Descriptive, Surigao City, Philippines
Study on the reaction mechanism and the static injection chemiluminescence method for detection of acetaminophen
Authors: Wu Yongjun , Zhang Huili , Yu Songcheng , Yu Fei , Li Yanqiang , Zhang Hongquan , Qu Lingbo , Harrington Peter de B. 
Published: February 2013

ABSTRACTAcetaminophen, also called paracetamol, is found in Tylenol, Excedrin and other products as over–the‐counter medicines. In this study, acetaminophen as a luminol signal enhancer was used in the chemiluminescence (CL) substrate solution of horseradish peroxidase (HRP) for the first time. The use of acetaminophen in the luminol–HRP–H2O2 system affected not only the intensity of the obtained signal, but also its kinetics. It was shown that acetaminophen was to be a potent enhancer of the luminol–HRP–H2O2 system. A putative enhancement mechanism for the luminol–H2O2–HRP–acetaminophen system is presented. The resonance of the nucleophilic amide group and the benzene ring of acetaminophen structure have a great effect on O‐H bond dissociation energy of the phenol group and therefore on phenoxyl radical stabilization. These radicals act as mediators between HRP and luminol in an electron transfer reaction that generates luminol radicals and subsequently light emission, in which the intensity of CL is enhanced in the presence of acetaminophen. In addition, a simple method was developed to detect acetaminophen by static injection CL based on the enhanced CL system of luminol–H2O2–HRP by acetaminophen. Experimental conditions, such as pH and concentrations of substrates, have been examined and optimized. The proposed method exhibited good performance, the linear range was from 0.30 to 7.5 mM, the relative standard deviation was 1.86% (n = 10), limit of detection was 0.16 mM and recovery was 99 ± 4%. Copyright © 2013 John Wiley & Sons, Ltd.
Relationship between procedural adverse events associated with cardiac catheterization for congenital heart disease and operator factors: Results of a multi‐institutional registry (C3PO)
Authors: Holzer Ralf J. , Gauvreau Kimberlee , Kreutzer Jacqueline , Moore John W. , McElhinney Doff B. , Bergersen Lisa 
Published: February 2013

BackgroundData examining the effect of operator years in practice and volume on adverse events (AE) after cardiac catheterization in patients with congenital heart disease is limited.Methods and ResultsData were prospectively collected using a multi‐center registry (C3PO). 10,885 catheterizations performed between 02/07 and 06/10 at eight institutions were included. AE rates were risk‐adjusted for hemodynamic vulnerability, procedure type risk group, and age and compared between operators with different years in practice (YIP) and volume. AE occurred in 13% of procedures. Operators with less than five YIP had higher adjusted odds of any AE (OR 1.42, 95% CI 1.14–1.77) or a high severity AE (OR 1.35, 95% CI 1.04–1.75), when compared with operators with 5 to less than 25 YIP (5 < 25), while operators with ≥25 YIP had higher odds of a high severity (but not any) AE (OR 1.39, 95% CI 1.08–1.80). Operators with <5 YIP had a higher percentage of preventable AE (out of all AE, 16% vs. 8%, P < 0.001) as well as higher odds of vascular or cardiac trauma (OR 1.81, 95% CI 1.11–2.97), or technical AE (OR 1.98, 95% CI 1.31–2.99) when compared with operators with 5 < 25 YIP. There was no consistent relationship between operator volume, and incidence of AE.ConclusionsOperators with less than 5 years in practice have higher risk‐adjusted AE rates. While an important consideration in guiding and mentoring operators with fewer years in practice, it is important to emphasize that reporting adverse events does not take into account procedural efficacy. © 2013 Wiley Periodicals, Inc.
Transcatheter closure of large atrial septal defects in children using the left atrial disc engagement–disengagement technique (LADEDT)—technical considerations and short term results
Authors: Pinto Robin , Jain Shreepal , Dalvi Bharat 
Published: February 2013

ObjectiveTo report our experience of transcatheter closure (TCC) of large atrial septal defects (ASDs) in children using the left atrial (LA) disc engagement‐disengagement technique (LADEDT).MethodsThis is a retrospective study comprising 21 children diagnosed with large secundum ASDs. All of them had an attempt at TCC with the Amplatzer septal occluder (ASO) using LADEDT. They were assessed by clinical examination, ECG and echocardiography before the procedure, at 24 hours, 6 weeks, 6 months, and every 1 year after the device closure.ResultsThe median age of the cohort was 3 years (range 1–12 years). The weight ranged from 5 to 40 kg (median = 12 kg). The mean ASD diameter was 16.7 ± 4.3 mm. The median device size used was 22 mm (range 15–40 mm). The device was successfully placed from the superior pulmonary vein (left: 12; right: 4) and the LA appendage (LAA) in 2. In three patients the technique failed and we had to resort to the balloon assisted technique (BAT) for a successful deployment. The number of attempts for deployment ranged from 1 to 4 (median 2). Despite appropriate placement, the device was not released in one patient because of deficient and floppy inferior margin. One patient had worsening of mitral regurgitation from mild to moderate grade without further progression till last follow up. There were no other major complications during the follow up (6.2 ± 2.4 months) period.ConclusionTCC of large ASDs in small children using the LADEDT is predictable, reproducible, relatively simple, safe, and effective. © 2013 Wiley Periodicals, Inc.
Short and long term complications of device closure of atrial septal defect and patent foramen ovale: Meta‐analysis of 28,142 patients from 203 studies
Authors: Abaci Adnan , Unlu Serkan , Alsancak Yakup , Kaya Ulker , Sezenoz Burak 
Published: February 2013

BackgroundDevice closure of atrial septal defect (ASD) and patent foramen ovale (PFO) are both associated with short‐ and long‐term complications. Our knowledge of the complication rates of ASD and PFO closure is limited. Our objective was to review the peri‐procedural and long‐term complications of ASD and PFO closure.MethodsMedline, EMBASE, and Scopus databases were searched between 1973 and 2012. A total of 28,142 patients from 203 case series were included. Of these 203 articles, 111 were reporting ASD closure, 61 were reporting PFO closure, and 31 were reporting both. Pooled incidence rates of cardiac complications were calculated separately for peri‐procedural and at follow‐up.ResultsPeri‐procedural major complications were reported from 0% to 9.4%, with a pooled estimate rate of 1.4% (95% CI: 1.3–1.6%). It was 1.6% (95% CI: 1.4–1.8%) in ASD group, 1.1% (95% CI: 0.9–1.3%) in PFO group, and 1.3% (95% CI: 0.9–1.9%) in ASD/PFO group. The most common major complication was the device embolization requiring surgery. Peri‐procedural minor complications were reported with a pooled estimate rate of 1.4% (95% CI: 1.2–1.7%). It was 1.6% (95% CI: 1.2–2.1%) in ASD group, 1.3% (95% CI: 1.0–1.7%) in PFO group, and 1.5% (95% CI: 1.1–1.2.1%) in ASD/PFO group. The most frequent major complications at follow‐up were cerebrovascular events [1.3% (95% CI: 1.1–1.6%)] and device thrombosis [1.2% (95% CI: 1.0–1.4%)]. Both were more frequent in PFO group.ConclusionDevice closure of ASD and PFO are associated with non‐negligible serious complications, both in early and long‐term. © 2013 Wiley Periodicals, Inc.
Regularization techniques on least squares non‐uniform fast Fourier transform
Authors: Gibiino Fabio , Positano Vincenzo , Landini Luigi , Santarelli Maria Filomena 
Published: February 2013

SUMMARYNon‐Cartesian acquisition strategies are widely used in MRI to dramatically reduce the acquisition time while at the same time preserving the image quality. Among non‐Cartesian reconstruction methods, the least squares non‐uniform fast Fourier transform (LS_NUFFT) is a gridding method based on a local data interpolation kernel that minimizes the worst‐case approximation error. The interpolator is chosen using a pseudoinverse matrix. As the size of the interpolation kernel increases, the inversion problem may become ill‐conditioned. Regularization methods can be adopted to solve this issue. In this study, we compared three regularization methods applied to LS_NUFFT. We used truncated singular value decomposition (TSVD), Tikhonov regularization and L1‐regularization. Reconstruction performance was evaluated using the direct summation method as reference on both simulated and experimental data. We also evaluated the processing time required to calculate the interpolator. First, we defined the value of the interpolator size after which regularization is needed. Above this value, TSVD obtained the best reconstruction. However, for large interpolator size, the processing time becomes an important constraint, so an appropriate compromise between processing time and reconstruction quality should be adopted. Copyright © 2013 John Wiley & Sons, Ltd.
Meta‐analysis reveals evolution in invasive plant species but little support for Evolution of Increased Competitive Ability (EICA)
Authors: Felker‐Quinn Emmi , Schweitzer Jennifer A. , Bailey Joseph K. 
Published: February 2013

AbstractEcological explanations for the success and persistence of invasive species vastly outnumber evolutionary hypotheses, yet evolution is a fundamental process in the success of any species. The Evolution of Increased Competitive Ability (EICA) hypothesis (Blossey and Nötzold 1995) proposes that evolutionary change in response to release from coevolved herbivores is responsible for the success of many invasive plant species. Studies that evaluate this hypothesis have used different approaches to test whether invasive populations allocate fewer resources to defense and more to growth and competitive ability than do source populations, with mixed results. We conducted a meta‐analysis of experimental tests of evolutionary change in the context of EICA. In contrast to previous reviews, there was no support across invasive species for EICA's predictions regarding defense or competitive ability, although invasive populations were more productive than conspecific native populations under noncompetitive conditions. We found broad support for genetically based changes in defense and competitive plant traits after introduction into new ranges, but not in the manner suggested by EICA. This review suggests that evolution occurs as a result of plant introduction and population expansion in invasive plant species, and may contribute to the invasiveness and persistence of some introduced species.
Comparing constitutive and induced costs of symbiont‐conferred resistance to parasitoids in aphids
Authors: Vorburger Christoph , Ganesanandamoorthy Pravin , Kwiatkowski Marek 
Published: February 2013

AbstractHost defenses against parasites do not come for free. The evolution of increased resistance can be constrained by constitutive costs associated with possessing defense mechanisms, and by induced costs of deploying them. These two types of costs are typically considered with respect to resistance as a genetically determined trait, but they may also apply to resistance provided by ‘helpers’ such as bacterial endosymbionts. We investigated the costs of symbiont‐conferred resistance in the black bean aphid, Aphis fabae (Scopoli), which receives strong protection against the parasitoid Lysiphlebus fabarum from the defensive endosymbiont Hamiltonella defensa. Aphids infected with H. defensa were almost ten times more resistant to L. fabarum than genetically identical aphids without this symbiont, but in the absence of parasitoids, they had strongly reduced lifespans, resulting in lower lifetime reproduction. This is evidence for a substantial constitutive cost of harboring H. defensa. We did not observe any induced cost of symbiont‐conferred resistance. On the contrary, symbiont‐protected aphids that resisted a parasitoid attack enjoyed increased longevity and lifetime reproduction compared with unattacked controls, whereas unprotected aphids suffered a reduction of longevity and reproduction after resisting an attack. This surprising result suggests that by focusing exclusively on the protection, we might underestimate the selective advantage of infection with H. defensa in the presence of parasitoids.
Climate Policy Integration: a Case of Déjà Vu?
Authors: Adelle Camilla , Russel Duncan 
Published: February 2013

ABSTRACTClimate change is a complex cross‐cutting problem that necessitates a high level of policy coordination. One proposed strategy for dealing with such issues is policy integration or mainstreaming. Environmental Policy Integration (EPI) was heralded as one of the key features of sustainable development. However, in recent years Climate Policy Integration (CPI) has come to the fore. This article argues that CPI is an emerging concept that has received insufficient attention in the literature, despite gathering increasing prominence in policy circles. In particular, the precise nature of the relationship between EPI and CPI is still unclear. This article compares CPI with EPI in order to systemically unpack what CPI means both conceptually and in practice. The article finds that CPI is less about ambitious and expansive integration across all policy sectors and more about engaging a narrower set of sectors to work together in particular ways to meet specific goals. Copyright © 2013 John Wiley & Sons, Ltd and ERP Environment.
A Route to Azafluoranthene Natural Products Through Direct Arylation
Authors: Ponnala Shashikanth , Harding Wayne W. 
Published: February 2013

AbstractMicrowave‐assisted direct arylation reactions were successfully employed in the synthesis of azafluoranthene alkaloids for the first time. Direct arylation reactions on a diverse set of phenyltetrahydroisoquinolines produces the indeno[1,2,3‐ij]isoquinoline nucleus required towards a high‐yielding azafluoranthene synthesis. The method was used as a key step in the efficient preparation of the natural products rufescine and triclisine. As demonstrated herein, this synthetic approach should be generally applicable to the preparation of natural and un‐natural azafluoranthene alkaloids as well as azafluoranthene‐like isoquinoline alkaloids.
SNR‐dependent radius control sphere detection for MIMO systems and relay networks
Authors: Han Shuangshuang , Tellambura Chintha , Cui Tao 
Published: February 2013

AbstractA new sphere decoder algorithm for uncoded spatial multiplexing multiple‐input multiple‐output (MIMO) systems is proposed. It overcomes the drawbacks of traditional sphere decoders: variable complexity and high complexity in low signal‐to‐noise ratios (SNRs). Its main novelty lies in scaling the search radius by a heuristic SNR‐dependent factor. This new SNR‐dependent radius control sphere decoder offers near maximum likelihood performance over the entire range of SNRs, while keeping its complexity roughly constant. This algorithm also incorporates channel ordering to save complexity. To quantify the variability of complexity, the normalised variance of the complexity is evaluated. This algorithm is also extended for joint iterative detection and decoding in coded MIMO systems and for MIMO‐relay networks. Simulation results and theoretical analysis demonstrate the benefits of the proposed algorithm.Copyright © 2013 John Wiley & Sons, Ltd.
The synergistic effect of ribose, carnosine, and ascorbic acid on the sensory and physico‐chemical characteristics of minced bison meat
Authors: Aliani Michel , Ryland Donna , Williamson Jennifer , Rempel Natalie 
Published: February 2013

AbstractIngredients such as ascorbic acid used to preserve redness of the raw meat, and carnosine and ribose used for flavor improvement have been incorporated into minced meats to increase consumer acceptance. The objective of this study was to investigate the possible synergistic effect of ascorbic acid, carnosine, and ribose on the sensory and physico‐chemical characteristics of minced bison meat. Samples included control (Co) ±1% carnosine (C), 0.1% ascorbic acid (A), 2% ribose (R) (w/w), and combinations of RC, RA, RCA in the same concentrations as the single ingredient samples. A trained sensory panel (n = 7) measured the intensity of the aromas and flavors of salty, sour, beef, and liver of the bison patties. A consumer acceptance panel (n = 59) evaluated color, aroma, flavor, texture, and overall acceptability of the patties. Hunterlab colorimetry, shear force, cook loss, and drip loss percentage were measured on the cooked patties, and color and pH on the raw patties. The sample containing 2% ribose (R), 1% carnosine (C), and 0.1% ascorbic acid (A) in combination (RCA) showed a significantly higher consumer acceptance for aroma, which could possibly be attributed to the high beef aroma intensity measured by the descriptive analysis panel. RCA had the highest color acceptance which may be related to the high a* value for the cooked sample. RCA also had high overall acceptance corresponding to “like slightly.” Raw and cooked color values, shear force, pH, cook loss and drip loss percentages, and aroma and flavor attribute intensities for RCA were not significantly different from the control sample. The synergistic effect of ribose, carnosine, and ascorbic acid may positively affect the aroma and color of minced bison meat leading to higher overall acceptability without compromising sensory and physico‐chemical quality.
Biological and functional properties of proteolytic enzyme‐modified egg protein by‐products
Authors: Pokora Marta , Eckert Ewelina , Zambrowicz Aleksandra , Bobak Łukasz , Szołtysik Marek , Dąbrowska Anna , Chrzanowska Józefa , Polanowski Antoni , Trziszka Tadeusz 
Published: February 2013

AbstractEnzymatic hydrolysis led to improve functional properties and biological activity of protein by‐products, which can be further used as protein ingredients for food and feed applications. The effects of proteolytic enzyme modification of egg‐yolk protein preparation (YP) and white protein preparation (WP), obtained as the by‐products left during the course of lecithin, lysozyme, and cystatin isolation on their biological and functional properties, were evaluated by treating a commercial Neutrase. The antihypertensive and antioxidative properties of YP and WP hydrolysates were evaluated based on their angiotensin‐converting enzyme (ACE)‐inhibitory activity and radical scavenging (DPPH) capacity, ferric reducing power, and chelating of iron activity. The functionality of obtained hydrolysates was also determined. Neutrase caused a degree of hydrolysis (DH) of YP and WP by‐products: 27.6% and 20.9%, respectively. In each of them, mixture of peptides with different molecular masses were also observed. YP hydrolysate showed high levels of antioxidant activity. The scavenging capacity, ferric reducing power, and chelating capacity were observed at the level: 0.44 μmol/L Trolox mg−1, 177.35 μg Fe2+ mg−1, and 549.87 μg Fe2+ mg−1, respectively. YP hydrolysate also exhibited significant ACE‐inhibitory activity, in which the level was 59.2 μg. Protein solubility was significantly improved as the DH increased. WP hydrolysate showed high water‐holding capacity of 43.2. This study indicated that YP and WP hydrolysates could be used in foods as natural antioxidants and functionality enhancers.