bluuebunny/crossref_metadata_2025_split huggingface dataset:
The effect of dysmenorrhea severity and interference on reactions to experimentally-induced pain
Authors: Rogers S. K. , Nichols K. L. , Ahamadeen N. , Shanahan M. L. , Rand K. L. 
Published: July 2024

IntroductionDysmenorrhea is associated with increased risk of chronic pain and hyperalgesia. Menstruating individuals with dysmenorrhea are more likely to have elevated pain reactivity when experiencing experimental pain, than those without. However, no study has examined intragroup differences in reactions to experimentally induced pain for individuals with dysmenorrhea. The main aim of this study was to examine the relative roles of dysmenorrhea severity and interference in the experience of experimentally-induced pain.MethodsParticipants were 120 menstruating individuals involved in a larger research study examining the influence of expectations on experimentally-induced pain. As part of the study, participants completed an online questionnaire regarding demographic and menstrual information and participated in a cold pressor task. Participants were randomized into four groups based on the manipulation of two independent variables: (1) high vs. low expectations about pain severity (pain-expectations); (2) and high vs. low expectations about one's pain tolerance (self-expectations). Participants verbally rated their pain severity throughout the cold pressor task using a 0–10 scale. Regression analyses were conducted examining the relationships between dysmenorrhea experience (i.e., average severity and interference) and cold pressor data [pain severity ratings and pain tolerance (i.e., total time in the cold pressor)], controlling for the manipulated expectations and age. Then, moderation analyses were conducted examining expectation group differences.ResultsWhen controlling for manipulated expectations and age, dysmenorrhea severity significantly predicted initial pain severity rating (p = 0.022) but did not predict final pain severity rating (p = 0.263) or pain tolerance (p = 0.120). Dysmenorrhea interference did not predict initial pain severity rating (p = 0.106), final pain severity rating (p = 0.134), or pain tolerance (p = 0.360). A moderation analysis indicated that the relationship between dysmenorrhea severity and initial pain severity rating was not moderated by pain-expectations, χ2(1) = 0.412, p = 0.521.DiscussionDuring an experimentally-induced pain task, dysmenorrhea severity but not interference predicted initial pain severity rating, such that higher levels of dysmenorrhea severity predicted greater initial pain severity rating. This suggests individuals with more severe dysmenorrhea pain may experience greater initial sensitivity to pain and be at risk for increased sensitivity to acute pain and potentially the development of chronic pain.
Seriousness and outcomes of reported adverse drug reactions in old and new antiseizure medications: a pharmacovigilance study using EudraVigilance database
Authors: Girgis Michael Magdy Fahmy , Farkasinszky Gergely , Fekete Klára , Fekete István , Vecsernyés Miklós , Bácskay Ildikó , Horváth László 
Published: July 2024

Introduction: Epilepsy is a widespread disease requiring long-term drug treatment. The aim of this study was to collect information on reported suspected adverse drug reactions (sADRs) of antiseizure medications (ASMs) and study their seriousness and outcomes in various system organ classifications (SOCs). We intended to compare old and new ASMs’ ADRs.Methods: Using EudraVigilance (EV) database, we extracted line listings of reported sADRs with different ASMs over the period from January 2012 to December 2021. The list of ASMs was compiled according to the Anatomical therapeutic chemical classification system. The Medical Dictionary for Regulatory Activities version 24.0 was used for determining the SOCs of individual reported preferred terms (PTs) sADRs. In addition, we calculated the Reporting Odds Ratio (ROR), 95% confidence interval (95% CI), p-value (statistically significant if p&lt; 0.05) and chi-square statistics.Results: A total of 276,694 reports were contained in the exported line listings which included 1,051,142 individual sADRs reported as PTs such as seizure (3.49%), drug ineffective (2.46%), somnolence (1.32%), dizziness (1.29%) and represented four SOCs: nervous system disorders (19.26%), general disorders and administration site conditions (14.39%), psychiatric disorders (11.29%) and injury, poisoning and procedural complications (9.79). Among patients, the age group between 18 and 64 years had the highest percentage (52.40%), followed by those aged over 64 years (18.75%). Of all the reported PTs, 882,706 (83.98%) had reported seriousness. Old ASMs had a significant positive association with “caused/prolonged hospitalisation”, “congenital anomaly”, “disabling”, “life threatening” and “results in death”, while new ASMS with ‘other medically important condition’. There were 386 (0.04%) PTs related to Sudden Unexpected Death in Epilepsy (SUDEP).Conclusion: In our study, we examined 10 years’ reported sADRs of ASMs in the EV international database. The majority of PTs were serious. Old ASMs were generally more commonly associated with undesired outcomes and seriousness. Considering their expected seriousness and outcomes, the safety profile of the different ASMs, can play a cardinal role in the selection of ASMs.
Conduction system pacing upgrade versus biventricular pacing on pacemaker-induced cardiomyopathy: a retrospective observational study
Authors: Pei-pei Ma , Ying Chen , Yi-heng Yang , Guo-cao Li , Cheng-ming Ma , Qing Fa , Lian-jun Gao , Yun-long Xia , Ying-xue Dong 
Published: July 2024

Objective: The feasibility of the conduction system pacing (CSP) upgrade as an alternative modality to the traditional biventricular pacing (BiVP) upgrade in patients with pacemaker-induced cardiomyopathy (PICM) remains uncertain. This study sought to compare two modalities of CSP (His bundle pacing (HBP) and left bundle branch pacing (LBBP)) with BiVP and no upgrades in patients with pacing-induced cardiomyopathy.Methods: This retrospective analysis comprised consecutive patients who underwent either BiVP or CSP upgrade for PICM at the cardiac department from 2017 to 2021. Patients with a follow-up period exceeding 12 months were considered for the final analysis.Results: The final group of patients who underwent upgrades included 48 individuals: 11 with BiVP upgrades, 24 with HBP upgrades, and 13 with LBBP upgrades. Compared to the baseline data, there were significant improvements in cardiac performance at the last follow-up. After the upgrade, the QRS duration (127.81 ± 31.89 vs 177.08 ± 34.35 ms, p &lt; 0.001), NYHA class (2.28 ± 0.70 vs 3.04 ± 0.54, p &lt; 0.05), left ventricular end-diastolic diameter (LVEDD) (54.08 ± 4.80 vs 57.50 ± 4.85 mm, p &lt; 0.05), and left ventricular ejection fraction (LVEF) (44.46% ± 6.39% vs 33.15% ± 5.25%, p &lt; 0.001) were improved. There was a noticeable improvement in LVEF in the CSP group (32.15% ± 3.22% vs 44.95% ± 3.99% (p &lt; 0.001)) and the BiVP group (33.90% ± 3.09% vs 40.83% ± 2.99% (p &lt; 0.001)). The changes in QRS duration were more evident in CSP than in BiVP (56.65 ± 11.71 vs 34.67 ± 13.32, p &lt; 0.001). Similarly, the changes in LVEF (12.8 ± 3.66 vs 6.93 ± 3.04, p &lt; 0.001) and LVEDD (5.80 ± 1.71 vs 3.16 ± 1.35, p &lt; 0.001) were greater in CSP than in BiVP. The changes in LVEDD (p = 0.549) and LVEF (p = 0.570) were similar in the LBBP and HBP groups. The threshold in LBBP was also lower than that in HBP (1.01 ± 0.43 vs 1.33 ± 0.32 V, p = 0.019).Conclusion: The improvement of clinical outcomes in CSP was more significant than in BiVP. CSP may be an alternative therapy to CRT for patients with PICM. LBBP would be a better choice than HBP due to its lower thresholds.
Benefits and functionality of an interorganisational workplace health management network – insights from the companies’ perspective
Authors: Hente Luisa , Schlesinger Torsten 
Published: July 2024

IntroductionWorkplace health management (WHM) is a worthwhile investment for companies. Nevertheless, the implementation of health-promoting interventions remains limited, especially in small and medium-sized enterprises. Interorganisational networks could be a promising way to raise awareness of the advantages of implementing WHM. Therefore, the aim of this study is to analyse the perceived functionality and benefits of a regional WHM network from companies’ perspective and to present initial results on this specific topic.MethodsAn explorative qualitative case study was conducted analysing ERZgesund, a WHM network in a rural region in Germany. Twenty-two companies that participated in the network were interviewed about their experiences and perceived advantages and disadvantages participating in the WHM network ERZgesund.ResultsThe findings show that the network has raised awareness about WHM among the companies, provides opportunities for exchange of knowledge and experiences, and generates or strengthens collaboration. The positive effects were enhanced by the network’s structure, such as regionality and a direct contact person. Nevertheless, some companies stated that they would welcome a higher level of participation and transparency.ConclusionOverall, it becomes clear that a WHM network can be a valuable tool to emphasize the relevance of WHM to companies. Therefore, further studies should validate and intensify the research on WHM networks to ensure a long-term benefit from the network.
Near miss road traffic accidents and associated factors among truck drivers in Gamo zone, southern Ethiopia by using a contributory factors interaction model
Authors: Bekelcho Tariku , Birgoda Gebremaryam Temesgen , Leul Hawi , Maile Maechel , Alemayehu Micheal , Olani Ararso Baru 
Published: July 2024

BackgroundRoad traffic accidents (RTAs) are among the leading causes of injuries, fatalities, and the resulting increase in financial burdens worldwide. Every year, RTAs cause numerous serious injuries and fatalities in Ethiopia. it is important to understand how prevalent near-miss crash accidents are, and which by definition could have injured the victim but did not result in an actual accident. The determinants of these near-misses are essential in road crash accident reduction strategies. In spite of the fact that near-miss accidents are much more common than actual losses or injuries, very little research has been conducted on them. Thus, this study was intended to assess the near-miss accidents and associated factors among truckers in Gamo zone, southern Ethiopia.MethodologyThe community-based cross-sectional study was employed from May 12 to July 10,2022, using a structured interviewer-administered questionnaire. A simple random sampling technique was used to select participants. The data were analyzed using the statistical package for social sciences. A binary and multivariate logistic regression model was used to identify the determinants of near-miss accidents. A statistical significance level was set at p &lt; 0.05.ResultsAbout 72.5% of truckers had experienced near-miss road traffic accidents. The majority of the near-miss accidents were caused by speeding, followed by driving on the wrong side of the road and skidding, 65 (22.6%), 39 (13.5%), and 38 (13.2%), respectively. Driving frequency per week, location of accidents, condition of the road, sleeping status, and weather conditions were significantly associated with near-miss accidents.ConclusionThe prevalence of near-miss accidents is high in the Gamo zone. Being a younger and less educated driver, high driving frequency per week, driving on major roads and junctions, foggy weather, and inadequate sleep all contribute to the occurrence of accidents. Road safety measures that could address these identified factors are required to mitigate potential RTAs.
Relationship between domain-specific physical activity and cognitive function in older adults – findings from NHANES 2011–2014
Authors: Wu Sijun , Wang Lin , Liu Shijie , Qi Juancai , Shi Fengrui , Zhuang Huiqi , Qian Youling , Mei Linqi , Zhang Maolin 
Published: July 2024

ObjectiveTo determine the relationship between domain-specific physical activity (PA) (e.g., occupational PA [OPA], transport-related PA [TPA], and recreational PA [RPA]) and cognitive function in older adults.MethodsThe data was obtained from the 2011–2014 cycle of the NHANES. We utilized weighted multivariate linear regression models among the included 2,924 people aged 60 years or older for our purposes.ResultsRPA and total PA according to WHO guidelines were associated with verbal fluency (RPA β: 1.400, 95% CI: 0.776, 2.024, p = 0.002; total PA β: 1.115, 95% CI: 0.571, 1.659, p = 0.001), processing speed and executive function (RPA β: 2.912, 95% CI. 1.291, 4.534, p = 0.005; total PA β: 2.974, 95% CI: 1.683, 4.265, p &lt; 0.001) were positively correlated, and total PA was correlated with delayed memory performance (β: 0.254, 95% CI: 0.058, 0.449, p = 0.019). No significant association was observed between OPA, TPA, and various aspects of cognitive function among individuals over 60 years.ConclusionThere was no noteworthy correlation discovered between OPA and TPA in relation to cognitive function. However, RPA and total PA exhibited significant associations with verbal fluency, processing speed, and executive function. Additionally, maintaining PA levels ranging from 600 to 1,200 MET-min/week would yield the most favorable outcomes for cognitive function.
How adverse childhood experiences impact the professional quality of life of residential care workers: resilience as a mediator for burnout, secondary traumatic stress, and compassion satisfaction
Authors: Milne Lise , Ratushniak Adrienne , Nguyen Hannah 
Published: July 2024

IntroductionThe well-being of trauma-affected children and youth in residential care settings is contingent upon the well-being of the workers who care for them, who are increasingly expected to provide care in a trauma-informed manner. The well-being of residential care workers (RCWs) may be impacted by their own histories of adversity, their capacity individually and collectively to navigate to resources that sustain their well-being (resilience), and current perceptions of their professional quality of life.ObjectiveThis study aimed to fill a research gap by canvassing the perspectives of RCWs to determine what and how they need to be supported in their work. We sought to better understand what personal (adverse childhood experiences, resilience) and professional (compassion satisfaction, burnout, secondary traumatic stress) experiences and capacities they bring into their work that might impact the quality of care they provide to children and youth.MethodA sample of 226 residential care workers from four residential care organizations across three Canadian provinces completed a self-report questionnaire to provide a portrait of their history of adverse childhood experiences as measured by theACE questionnaire, which included two additional questions reflecting the more nuanced and expanded understanding of potential adversity in childhood in the Canadian context; their resilience, as measured by theAdult Resilience Measure; and compassion satisfaction, burnout, and secondary traumatic stress, as measured by theProfessional Quality of Life Measure. Mediation was conducted to examine whether and how resilience mediated the relationship between ACEs and professional quality of life indicators.Results(1) RCWs reported experiencing ACEs at rates much higher than general population and norm samples, especially regarding the experience of 4–5+ ACEs, known to be a threshold for increased severity in negative outcomes; (2) RCWs experienced levels of resilience and indicators of professional quality of life similar to those in other human services professions serving trauma-impacted individuals; and (3) RCW resilience significantly mediated the relationship between ACEs and compassion satisfaction, burnout, and secondary traumatic stress, and had a significant total effect for the relationship between ACEs and secondary traumatic stress. These results suggest the importance of enhancing RCW resilience in multiple ways, mainly in their professional contexts. Recommendations for resilience enhancement and suggestions for future research are provided.
تأثير الخصائص الفردية على توجهات تبادل المعرفة ونواياها وسلوكياتها لدى الأكاديميين
Authors: خليل عمر , معروف ليلى , خليل نادية 
Published: July 2024

هدف الدراسة: تعد معرفة ممارسات مشاركة المعرفة (Knowledge Sharing) والعوامل التي يمكن أن تؤثر عليها أمراً حيوياً لجهود تعزيز مشاركة المعرفة في مؤسسات التعليم العالي. هدفت هذه الدراسة إلى الإجابة عن سؤالين رئيسين: (1) إلى أي مدى يحمل الأكاديميون في إحدى مؤسسات التعليم العالي الرائدة في الشرق الأوسط اتجاهات (Attitudes) مواتية تجاه مشاركة المعرفة، ويمارسون فعلاً هذه المشاركة، ويعتزمون مواصلة مشاركة المعرفة في المستقبل؟ (2) ما تأثير الخصائص الفردية، متمثلة في الجنس والعمر والمجال الأكاديمي والرتبة الأكاديمية والخبرة في التعليم العالي ومستوى التعليم، على اتجاهات الأكاديميين ونواياهم وسلوكياتهم المتعلقة بمشاركة المعرفة.تصميم/منهجية/طريقة الدراسة: استخدمت الدراسة الحالية أسلوب دراسة الحالات بالتطبيق على جامعة الكويت؛ بوصفها إحدى مؤسسات التعليم العالي الرائدة في الشرق الأوسط. وصممت استبانة بكل من اللغتين العربية والإنجليزية، واستخدمت لجمع بيانات الدراسة من أعضاء الهيئة الأكاديمية بالجامعة. تحتوي الاستبانة على سؤال واحد لقياس كل من الخصائص الفردية، وأسئلة متعددة لقياس كل من التوجهات تجاه مشاركة المعرفة وممارسات المشاركة الفعلية ونوايا المشاركة في المستقبل. عينة الدراسة وبياناتها: وزعت الاستبانة على أعضاء الهيئة الأكاديمية في مختلف الكليات، وجمعت 207 استجابات كاملة، وتبلغ نسبة هذه العينة %14.5 من إجمالي عدد الأكاديميين بالجامعة. وللإجابة عن سؤالي الدراسة، عولجت البيانات إحصائياً باستخدام الإحصاء الوصفي وتحليل العوامل (Factor analysis) وتحليل التباين متعدد المتغيرات (MANOVA).نتائج الدراسة: أظهرت نتائج التحليل الإحصائي أن لدى الأكاديميين المشاركين في الدراسة توجهات مواتية تجاه مشاركة المعرفة مع زملائهم، ويشاركون المعرفة مع زملائهم عبر قنوات الاتصال التنظيمية والشخصية، ويعتزمون الاستمرار في مشاركة المعرفة في المستقبل. وبينت النتائج أيضاً أن الخصائص الفردية المتمثلة في الجنس والعمر والمجال الأكاديمي والمرتبة الأكاديمية والخبرة والمستوى التعليمي، لها تأثيرات فردية وتفاعلية متفاوتة على اتجاهات الأكاديميين تجاه مشاركة المعرفة، وممارسة المشاركة، ونوايا المشاركة في المستقبل. أصالة الدراسة: تقدم هذه الدراسة معلومات جديدة عن توجهات الأكاديميين ونواياهم وسلوكياتهم، بخصوص مشاركة المعرفة مع زملائهم في إحدى مؤسسات التعليم العالي الشرق الأوسطية (جامعة الكويت)، بالإضافة إلى تأثير عدد من الخصائص الفردية على هذه التوجهات والنوايا والسلوكيات. وخلافاً لنتائج الدراسات المماثلة السابقة، تؤكد نتائج هذه الدراسة أن تأثير كل من الخصائص الفردية غالباً ما يكون مرهوناً بتفاعلاتها مع الخصائص الأخرى؛ ومن ثم يجب تفسير التأثير الفردي لكل خصيصة على مشاركة المعرفة بشيء من الحذر.حدود الدراسة وتطبيقاتها: يجب تفسير نتائج هذه الدراسة ومحاولة تعميمها على مؤسسات أخرى في ضوء محدداتها، التي ترجع إلى أن هذه النتائج اعتمدت على بيانات عن الأكاديميين العاملين في مؤسسة تعليم عالٍ واحدة، وتم جمعها في نقطة زمنية واحدة. ومع ذلك، تمثل هذه النتائج إضافة مهمة إلى البناء المعرفي المتنامي حول توجهات مشاركة المعرفة ونواياها وممارساتها، وتأثير الخصائص الفردية عليها. كما أنها توفر أساساً ملائماً لصياغة سياسات تهدف إلى تعزيز فعالية مشاركة المعرفة بين الأكاديميين في مؤسسة التعليم العالي المدروسة وغيرها من مؤسسات التعليم العالي المماثلة.
Analysis of Demand for the Profession "crane operator in metallurgical production"
Authors: Костарева А.А. 
Published: July 2024

Статья посвящена вопросам анализа спроса на рабочую силу определенной профессии на рынке труда. Определена сущность спроса на труд, доказана актуальность темы тем, что металлургия является одной из системообразующих отраслей экономики России, а машинист крана одна из наиболее востребованных профессий отрасли. Дано описание трудовых функций, выполняемых работниками по данной профессии. Проанализирована средняя заработная плата по должностям и рейтинг профессии машинист крана металлургического производства на первый квартал 2019 года, в том числе перспективы профессии, входной барьер, уровень конкуренции и др. Выявлено, что заработная плата по данной профессии выше среднерыночных. Автор проанализировала динамику количества вакансий и резюме, размещенных на портале HeadHunter, и выявила превышение спроса на труд над предложением, что говорит о дефиците рабочей силы по данным профессиям. Далее определены проблемы кадрового обеспечения отрасли, в том числе старение персонала, достаточно высокий уровень текучесть кадров, несоответствие качества подготовки кадров требованиям работодателя. Автором предложено внедрение специальных программ профориентации для пропаганды и привлечения школьников и студентов.
The article is devoted to the analysis of the particular profession demand for labor on the labor market. The essence of the demand for labor is determined the topic relevance is proved by the fact that metallurgy is one of the backbone sectors of the Russian economy, and the crane operator is one of the most popular professions in the industry. The description of the labor functions performed by employees in this profession is given. The average salary by positions and the rating of the profession crane operator in metallurgical production were analyzed for the first quarter of 2019, including the profession prospects, entry barrier, competition level, etc. It was revealed that the salary for this profession is higher than the average. The author analyzed the dynamics of the number of vacancies and resumes posted on the HeadHunter portal, and revealed an excess of demand for labor over supply, which indicates a labor shortage in these professions. Further, the problems of staffing the industry were identified, including aging staff, a sufficiently high staff turnover level, and the mismatch between the training quality and the employers requirements. The author proposed the introduction of special career guidance programs for advocacy and attract schoolchildren and students.