bluuebunny/crossref_metadata_2025_split huggingface dataset:
Determining the Relationship Between Gynecologic Cancer Awareness and Health Literacy Among Women of Reproductive Age: A Descriptive Study
Authors: Duman Fatma Nur , Ozdemir Ayse , Gölbaşı Zehra 
Published: August 2024

Abstract

Purpose
To determine the relationship between gynecologic cancer awareness and health literacy among women of reproductive age.
Methods
The study was conducted in a descriptive design and involved 510 women. Data collection utilized the “Personal Information Form”, “Gynecologic Cancer Awareness Scale (GCAS)” and “Health Literacy Scale (HLS)”, gathered. Pearson correlation and linear regression analyses, independent samples t-test, one-way analysis of variance and post-hoc analyses were employed for data analysis. Effect sizes were calculated using Eta squared (η²) coefficients.
Results
The mean total score of women on the GCAS was 154.42 ± 18.27, while the mean total score on the HLS was 57.07 ± 7.86. Significant differences were observed in women's GCAS total scores concerning age, perceived income status, and history of gynecological examination, whereas significant differences were noted in HLS total scores concerning age, educational status, marital status, and perceived income status. A weak positive correlation was detected betwixt women's GCAS and HLS total scores. It was determined that 20.8% of the total variation in gynecologic cancer awareness level was explained by health literacy.
Conclusion
Women exhibit an above-average level of awareness regarding gynecologic cancers. Health literacy level contributes to an increase in gynecologic cancer awareness.
Mapping of absolute stresses around two California earthquakes reveals a very weak crust
Authors: Zhang Siyuan , Houston Heidi , Wang Binhao , Zhang Hao 
Published: August 2024

Abstract

Absolute amplitudes of shear stresses that drive crustal earthquakes are not well known. There is a long-standing divergence between the values inferred from lab experiments and stress changes during faulting. Two large earthquakes near Ridgecrest, California with M6.4 and 7.1 provide a natural laboratory to determine the in-situ average shear stress in the crust off the main faults. Here we use the change in faulting geometries of abundant small earthquakes together with stress changes imposed by doublet slip to determine full deviatoric stress tensors both before and after it. We first invert suites of focal mechanisms for stress orientations and ratios between eigenvalues. We then invert for the 3-D full deviatoric tensors constrained by the stress orientations, stress ratios, and the coseismic stress change due to the doublet. We applied this method using two doublet slip models and two endmember approaches: first dividing the region into 12 blocks surrounding the mainshock faults, and second performing 9,200 separate inversions offset by ~ 1 km. To obtain reliable results, we use the 3-D relationship rather than a common 2-D strike-slip simplification, define inversion regions that do not cross the main faults, and include only high-quality events a few km away from the main faults to avoid large heterogeneities in the co-seismic stress change. Deviatoric stresses are only a few percent of levels expected at seismogenic depths from Byerlee friction, except for regions near the doublet hypocenters where they are up to only ~ 7.5%. Our approach yields strong evidence for a very weak continental crust, which bears on earthquake and geodynamic modeling, as well as earthquake recurrence behavior and hazard, suggesting near-complete stress drops in the mainshock doublet and a low chance of imminent large slips there.
Development of Mussaenda frondosa sepal infused functional tea with enhanced antioxidant and alpha amylase inhibitory activities
Authors: Nafla M. F.F. , Kananke T. C. , Perera M. G.A.N. 
Published: August 2024

Abstract

Mussaenda frondosa (MF) is an edible species of the genus Mussaenda (Rubiaceae) that contains a wide array of medicinal compounds. The present study was conducted to evaluate the physicochemical and functional properties of the MF sepals, to develop a novel herbal tea with improved functional properties. Remarkably high antioxidant and α-amylase inhibitory activities were exhibited by water and ethanol extracts of MF, subsequent to their high phenolic and flavonoid contents. None of the extracts showed a toxicity, as evaluated by brine shrimp lethality assay. A tea was formulated by blending different proportions of dry sepals of MF with black tea. The sensory analysis showed a significantly high level of acceptancy for the formula that containing 40% MF (MFT-40) with augmented phenolic contents, antioxidant and hypoglycemic activities. This study revealed the potential use of MF as a source for the development of new functional teas with enhanced health benefits.
Integrated metabolomics and transcriptomics reveal the role of calcium sugar alcohol in the regulation of phenolic acid biosynthesis in Torreya grandis nuts
Authors: Xie Qiandan , Jiang Zhengchu , Yu Chenliang , Wang Qi , Dai Wensheng , Wu Jiasheng , Yu Weiwu 
Published: August 2024

Abstract

Background：Torreya grandis, a prominent tree species of the autochthonous subtropical region of China, possesses a drupe-like fruit containing a nut that is rich in nutrients and bioactive compounds. However, the effect of calcium (Ca2+) sugar alcohol (CSA), a newly developed chelated Ca2+-fertilizer, on the secondary metabolism of phenolics in T. grandis nuts is largely unknown, for which transcriptomic and metabolomic analysis was carried out.
Results: Transcriptome sequencing detected 47,064 transcripts, and several phenolic acid biosynthesis pathway-related genes were identified. Correlation analysis showed that the four transcription factors, WRKY12, AP2-1, AP2-3, and AP2-4, were positively associated with the accumulation of phenolic acids. Furthermore, the binding of AP2-1 to the HCT promoter was confirmed using yeast one hybrid and dual-luciferase assays. Furthermore, the expression of HCT in Nicotiana enhanced the total flavonoid content.
Conclusions: Our results indicated that a new regulatory module, Ca2+–AP2–HCT, involved in the regulation of phenolic acid biosynthesis was revealed, expanding the understanding of the role of Ca2+ fertilizers in plant secondary metabolism.
Phytostabilisation of arsenic contaminated gold mine waste using the native species Juncus usitatus L.A.S Johnson, Poa labillardieri Steud and Themeda triandra Forssk
Authors: Besedin Julie A. , Khudur Leadin S. , Netherway Pacian , Krohn Christian , Juhasz Albert L. , Huslina Feizia , Besedin Darislav A. , Jansriphibul Kraiwut , Nahar Kamrun , Ball Andrew S. 
Published: August 2024

Abstract

Arsenic (As) contaminated gold mine waste represents a significant issue for ecosystem and human health, as it is a known carcinogen and environmental toxin. Bendigo in Victoria, Australia, has reported As concentrations up to 22,000 mg/kg, exceeding the national soil guidance values (100 mg/kg) by 220-fold. To reduce exposure and potential human health risk, remediation or risk management strategies are required. Traditional remediation, such as excavation and landfill, often fail to improve soil conditions and are expensive. Biological remediation using plants (phytoremediation) represents a cost-effective strategy that results in the restoration of soil function and ecosystem services. There is a need to identify native plants for phytoremediation as current research focuses on fern species, which are not suitable for Bendigo. This study aimed to identify a native by conducting a mesocosm experiment involving Juncus usitatus, Poa labillardieri, and Themeda triandra. Plants grew in mine waste for 100 days, all survived and bioaccumulated As in the roots (phytostabilisation). Poa labillardieri grew significantly more biomass (roots 0.24 ± 0.01 g; shoots 0.22 ± 0.03 g (d/w)) and bioaccumulated the most As (~100 mg/kg plant biomass). The bacterial community was investigated to assess soil health and As association. The rhizosphere microbiota stabilised after root colonisation for Poa labillardieri and Themeda triandra, as indicated by richness and evenness changes. The two dominant phyla were Actinobacteriota and Proteobacteria, which displayed As tolerance. A keystone taxon, Latescibacterota, exhibited a positive relative association with As remediation. Poa labillardieri is a good candidate for future phytostabilisation trials.
Preparation and rheological properties of a hydrophobically associating viscoelastic polymer with temperature and salt resistance via reversed-phase emulsion polymerization
Authors: chen shanshan , Lai Xiaojuan , Di Yiliang , Wu Zekun , Li Haibin , Chen Jiali , Wang Lei , Wen Xin 
Published: August 2024

Abstract

In some reservoirs, groundwater or formation water is exposed to high salinity salt solution and high underground temperature conditions. In high salinity environments,traditional fracturing fluid are prone to salt crystallization, salt deposition and colloidal particle aggregation.Moreover, In high temperature environment, additives and colloids in traditional fracturing fluids may degrade, fail or denature, resulting in the degradation of the fracturing fluid performance. Most of the fracturing fluids studied to date cannot meet the performance requirements of temperature and salt resistance simultaneously while ensuring a low cost.To solve this problem,using acrylamide (AM), acrylic acid (AA), 2-acrylamido-2-methylpropanesulfonic acid (AMPS), and the hydrophobic monomer allyl polyethylene glycol (APEG) as molecular skeletons, an associating viscoelastic polymer, p(AM/AA/AMPS/APEG), was prepared via inverse emulsion polymerization. The structure and morphology of the polymer were characterized via Fourier transform infrared spectroscopy, 1H nuclear magnetic resonance spectroscopy, scanning electron microscopy, and laser particle size analysis, and its rheological properties, particularly thixotropy and viscoelasticity, were evaluated. The p(AM/AA/AMPS/APEG) solution showed the characteristics of a viscoelastic fluid, as well as good temperature resistance at 160°C and a concentration of 0.8 wt.%. The viscosity of p(AM/AA/AMPS/APEG) was 64.88 and 56.77 mPa·s after shearing in 20000 mg/L NaCl solution and CaCl2 solution for 1 h at 140°C and 170 s− 1, respectively. With increasing polymer concentration, the intermolecular association efficiency of the hydrophobic groups and the apparent viscosity of the solution increased. The p(AM/AA/AMPS/APEG) polymer exhibited good thixotropy, salt resistance, temperature resistance, and shear resistance. This hydrophobically associating polymer shows good application prospects in the development and utilization of unconventional oil and gas resources.
Acoustic response characteristics of damage and instability precursors of rocks with different lithologies
Authors: Wang Chuangye , Sui QingRui , Chang Xinke , Yan Yuhang , Zhu Huangjin , Guo Yu 
Published: August 2024

Abstract

Uniaxial compression and acoustic emission (AE) tests were conducted on sandstone, marble, and granite specimens to investigate the damage and instability precursors of rocks with different lithologies. The AE event rate, autocorrelation coefficient and variance of AE event rate, proportion of main frequency signals of each level of AE, r value, and proportion of two types of AE signals were analysed to determine the damage and instability precursors of rocks with different lithologies during the loading process. Studies have revealed that the size of a rock’s AE low event rate missing portion is consistent with the order of the elastic modulus and peak stress of granite, marble, and sandstone, corresponding to the severity of the rock fracturing. The autocorrelation coefficient and variance of the event rate suggest that the damage precursors of three types of rock occur earlier and last longer as the rock strength increases. The low-frequency AE signals of the three types of rocks converge to large values when the rock approaches instability and failure. It should be noted that granite experiences a downward shift in the mid-frequency band before it experiences instability. The proportion of low-frequency AE signals initially decreases and then increases when the specimen is about to become unstable. In addition, at medium and high frequencies, it initially increases and then decreases. This phenomenon becomes more pronounced as the rock strength increases. Immediately before rock instability occurs, the r value is high, and a large number of shear-like AE events occur inside the rock, exacerbating the internal failure of the rock. The proportion of single peak AE signals and bimodal AE signals fluctuates, but their evolutionary trend is opposite. The AE signal with a single peak is a precursor to the occurrence of critical instability. It initially increases and then quickly decreases.
Role of New Generation Implantable Loop Recorders in Managing Undiagnosed Pediatric Cardiac Symptoms
Authors: Agudo-Montore Pedro , Stuart Graham , Wilson Deirdre , Spentzou Georgia , Sidiqqui Rabeea , Corcia Maria Cecilia Gonzalez 
Published: August 2024

Abstract

Importance: Pediatric cardiac symptoms such as palpitations, syncope, or seizure-like episodes pose diagnostic challenges for general pediatricians. These symptoms, though often benign, may reveal underlying arrhythmias or inherited cardiac conditions (ICCs), affecting the quality of life and limiting activity participation. Purpose: To determine the effectiveness and safety of implantable loop recorders (ILRs) in diagnosing and managing arrhythmias in pediatric patients. Methods: A retrospective cohort study conducted over an 8-year period from January 2016 to December 2023 in a single pediatric cardiology center. A cohort of 155 pediatric patients (median age 11.4 years) who underwent ILR implantation, selected based on symptoms such as palpitations, chest pain, or syncope, and those with previously recorded arrhythmias or high-risk ICCs. The primary outcomes were the diagnostic yield of ILRs for arrhythmias and subsequent changes in patient management. Diagnostic yield was defined as the detection of relevant arrhythmias, such as pauses of 3 seconds or longer, high-degree AV block, sinus node dysfunction, supraventricular tachycardia, ventricular tachycardia or inappropriate sinus tachycardia. Results: The median follow-up period was 2.3 years (845 days). Diagnostic arrhythmias were recorded in 60% of patients with symptom-activated transmissions and 80% of device-activated transmissions. Sinus pauses (37.5%) and VT (30%) were the most common arrhythmias detected. In patients with syncope (n = 76), 30% had relevant arrhythmias. In the palpitations group (n = 20), 35% had relevant arrhythmias. Approximately 80% of patients with ILR-diagnosed arrhythmias underwent targeted management, including medication changes and additional procedures. No significant complications were observed; minor complications occurred in 2.5% of patients. Conclusions: New generation ILRs are effective and safe for diagnosing and managing pediatric arrhythmias, providing significant reassurance to patients and families. Further studies are needed to evaluate the impact of ILRs on quality of life and sports participation in high-risk young patients.
Apolipoprotein E is a novel marker for chondrocytes in the growth plate resting zone
Authors: Otsuru Satoru , Kodama Joe , Oichi Takeshi , Wilkinson Kevin , Abzug Joshua , Kaito Takashi , Iwamoto-Enomoto Motomi , Iwamoto Masahiro 
Published: August 2024

Abstract

The resting zone (RZ) in mammalian growth plates is critical for maintaining and regulating chondrocyte turnover during longitudinal bone growth as a control tower and stem cell reservoir. Although recent lineage tracing studies have identified several markers for stem cells in the RZ, these markers only partially label chondrocytes in the RZ, suggesting that the resting chondrocytes (RCs) are a heterogeneous population with different types of stem cells. Since a comprehensive marker for RCs is still lacking, the RZ is generally determined based on ambiguous histological criteria, such as small and round chondrocytes without columnar formation, which may lead to inconsistencies among researchers. Therefore, in this study, we used single-cell RNA sequencing (scRNAseq) of growth plate chondrocytes followed by validation by fluorescence in situ hybridization (FISH) to precisely annotate cell clusters in scRNAseq and search for a marker of RCs. The scRNAseq analysis revealed that apolipoprotein E (Apoe) was the top-hit gene, which was ubiquitously expressed in the RC cluster. FISH confirmed that Apoe was exclusively localized to the histologically defined RZ. In newly generated Apoe-mCherry knock-in mice, we further confirmed that mCherry expression mirrored the distribution of Apoe-expressing chondrocytes in the RZ particularly after the formation of the secondary ossification center. These mCherry+ RCs were slow cycling in vivo and exhibited stem cell properties both in vitro and in vivo. Moreover, APOE was detected in human growth plate RCs. These findings suggest that Apoe is a novel pan-RC marker in both mouse and human growth plates.
Pressurized torrefaction of waste biomass to improve bio coal quality: Synergistic effect between animal waste and wood chips
Authors: Tshuma N. , Moyo L. B. , Mamvura T. A. , Simate G. , Danha G 
Published: August 2024

Abstract

Perennial global energy demands and the need to cut on emissions from fossil fuels has paved the way for alternative energy sources such as raw biomass and animal waste. In addition, there is limited research in deducing the impact of blending waste material to improve its characteristic properties using pressurized torrefaction. In this regard, this research explored the benefits of blending animal waste with wood chips to produce a bio-coal with improved properties. The process conditions investigated were temperature and pressure intervals of 200°C to 280°C and atmospheric pressure (AP) to 4MPa, respectively. The results showed that a positive adjustment in temperature and pressure improved the fixed carbon content of the blend almost threefold from 19.87–66.90% and the higher heating value (HHV) to 27.32MJ/kg from 13.90MJ/kg at mild torrefaction temperature of 280oC and gas pressure of 4MPa. Wood chips had an HHV of 27.00MJ/kg upon treatment due to the decomposition of hemicellulose and cellulose which enhanced the thermal stability, fixed carbon content and calorific value. However, animal waste had the least incremental increase in HHV (16.45MJ/kg) due to a high initial content of volatile substances and moisture. Moreover, pressurized torrefaction facilitated the decomposition of cellulose at a lower temperature than the typical range of 315-400oC if conducted at atmospheric pressure. Furthermore, the study showed that to overcome the drawbacks of having a lower fixed carbon and HHV for animal waste, blending animal waste with wood chips was effective in synthesizing bio-coal with improved properties like some coals.
Biopesticidal Properies of Heliotropium Indicum Leaf Extracts for Controlling Stored Grain Weevils
Authors: Adeniyi B. M , Kyenge B.A , Adah C. A , Kunle Ogumgbemi , Odeniyi T. A , Balogun D.A , Alejo A.O 
Published: August 2024

Abstract

The hexane, ethyl acetate, methanol and aqueous leaf extracts of Heliotropium indicum were screened for their biopesticidal activity against the weevils of rice, sorghum and maize grains. Each extract demonstrated promising efficacy in causing mortality at various concentrations (0.01 g/ml, 0.02 g/ml, 0.04 g/ml, and 0.08 g/ml) 24–96 h postexposure. Among the extracts, the methanol extract emerged as the most effective, exhibiting the highest mortality rate of 96.67% at a concentration of 0.08 g/ml, 96 h after exposure, comparable to the standard insecticide (cypermethrin 2.5 E.C). In contrast, the negative control, consisting of untreated grains, showed 1.67% mortality rate for Sitophilus zeamais 72 h post-exposure, which could be attributed to natural death. Additionally, the methanol, ethyl acetate, and aqueous extracts demonstrated mortality rates above 50%, reaching up to 90%, for Sitophilus zeamais. This level of effectiveness is similar to that of cypermethrin, indicating that Heliotropium indicum could be a valuable biopesticide for the postharvest management of stored grains. This study suggests the potential for these plant extracts to serve as natural alternatives to synthetic insecticides, offering a sustainable solution for pest control in stored grain protection. The novelty of this research lies in its comprehensive approach to utilizing multiple solvent extracts from a single plant species, highlighting the untapped potential of Heliotropium indicum in the development of eco-friendly biopesticides. This could pave the way for further investigations into other medicinal plants with similar properties, ultimately contributing to safer and more sustainable agricultural practices.
Integrating D-S Evidence Theory and Multiple Deep Learning Frameworks for Time Series Prediction of Air Quality
Authors: Feng Siling , Tang Le , Huang Mengxing , Wu Yuanyuan 
Published: August 2024

Abstract

Accurate prediction of air quality time series data is helpful to identify and warn air pollution events in advance. Although the current air quality prediction models have made some progress in improving the accuracy of prediction, due to the impact of specific pollutants or complex meteorological conditions, these models still have the problems of low prediction accuracy, robustness and generalization ability in univariate prediction. In order to solve these problems, this study proposes a framework that integrates D-S evidence theory and a variety of deep learning models. The air quality data of three representative cities with climate characteristics in China are obtained and five indicators on air pollutants are collected. The preprocessed data are divided by time length to form short-term, medium-term and long-term input data, and MLP, RNN, CNN, LSTM, BI-LSTM and GRU models are established respectively. By comparing the performance indicators of the six models, three most suitable models are selected to predict the short, medium and long-term data respectively. Taking the prediction results and reliability as the three evidence bodies of the theory, a fusion model based on D-S evidence theory is established. For the three performance indicators Mae, MSE and MAPE of the model, the best result of the fusion model increases the performance by 7.42\%, 4.25\% and 12.82\% compared with the sub optimal architecture. This shows that integrating D-S evidence theory and a variety of deep learning algorithms provides an effective method to accurately predict the long-term air quality level in most urban areas.
Harmonic Mean Cordial labeling of Some Special Graphs and Some Graphs Related to H-graph
Authors: Hathi Yesha M. , Javia Parth S. , Jariya Mahesh M. , Shukla Minal , Acharya Biswaranjan , Shah Mohd Asif , Mallik Saurav 
Published: August 2024

Abstract

All the graphs considered in this article are simple, connected and undirected. In this paper, we have proved the theorems on Harmonic Mean Cordial labeling 1 of switching of a vertex in a graph, duplication of a central vertex in a path, cycle, triangular snake graph, friendship graph, path union of a path and a cycle and at last, applications of HMC labeling in civil engineering, i.e., in building cable-stayed tied-arch bridges.
AMS Classification (2020): 05C78