bluuebunny/crossref_metadata_2025_split huggingface dataset:
Acute Augmentations to Psychological Therapies in Eating Disorders: A Systematic Review and Meta-Analysis
Authors: Pennesi Jamie-Lee , Johnson Catherine , Radünz Marcela , Wade Tracey D. 
Published: August 2024

Abstract
Purpose of Review
The purpose of this systematic review and meta-analysis was to examine the use and efficacy of acute augmentation therapies in eating disorders.

Recent Findings
A meta-analysis addressing this topic across psychological disorders found augmentation significantly improved therapy outcome with strongest findings for augmentations targeting biological mechanisms; however, only one study examined eating disorders.

Summary
Our systematic review identified 29 studies examining people with eating disorders (N = 1831 participants, 93.7% female), of which 17 RCTs (n = 1162 participants) were included in the meta-analysis. Small subgroups of acute augmentations were identified. Adding acute augmentations to an intervention was effective in 72.4% of studies, with a significant effect on eating disorder outcomes (Hedges’ g = 0.14, 95% CI: [0.02, 0.26]). Acute augmentation looks to be a promising approach regardless of weight status or whether it is added to treatment as usual or a single therapy approach.
Charting cancer’s course: revealing the role of diet, exercise, and the microbiome in cancer evolution and immunotherapy response
Authors: Martin-Quesada Ana Isabel , Hennessy Maeve A. , Gutiérrez Ana Cardeña 
Published: August 2024

Abstract
A variety of pathophysiological mechanisms exist by which physical exercise, nutrition, and the microbiome can impact the development of cancer and the response of tumor cells to systemic anti-cancer therapy. Physical exercise positively impacts the different stages of oncological disease and may improve overall survival and quality of life, reduce treatment-associated toxicity, and improve response to immunotherapy. Nutrition impacts quality of life, and novel nutritional regimens and their role in cancer treatment and outcomes are under active investigation. Finally, the microbiome may act as a predictor of response and resistance to immunotherapy. This comprehensive review delves into the interplay between these elements and their impact on oncological outcomes, emphasizing their role in modulating the immune system and enhancing the response to immunotherapy.
The data that support the findings of this study are openly available and referenced in the bibliography section.
Early Identification of Social, Emotional, and Behavioral Difficulties in Primary Schools: Explanations for Special Educational Needs Coordinators’ Different Practices
Authors: Jaspers-van der Maten Marloes L. , Rommes Els W. M. 
Published: August 2024

AbstractEarly identification of social, emotional, and behavioral difficulties (SEBDs) in children is essential to provide support and reduce the risk of negative outcomes. Schools are considered ideal settings to identify SEBDs, and in many countries special educational needs coordinators (SENCOs) play a pivotal role in this respect. Although SENCOs may contribute to improving school-based identification of SEBDs by adopting a more systematic approach, they have a multitude of tasks and considerable professional discretion. As a result, there are differences between SENCOs in the quality of their identification practices in terms of the frequency of observations, the maintenance of a four-eyes principle, and the utilization of specialist knowledge, affecting whether and when SEBDs are identified. The aim of this study was to examine what factors can explain differences in these practices for early identification of SEBDs. Using a narrative qualitative approach, we interviewed 34 primary school professionals, studied school policy documents and observed team meetings. Thematic analysis revealed that an interplay of the factors: (1) (conformity to) school regulations, (2) team continuity, and (3) personal characteristics, explains why SENCOs decide differently on who conducts observations, and when. Generally, SENCOs are more likely to conform to frequent observations by at least two observers utilizing specialist knowledge, when schools have regulations that clearly define by whom and when observations should take place, with competent, committed, proactive school staff conforming to those regulations, within a stable team. Although each factor is important but not essential to ensure these practices, personal characteristics of the SENCO can compensate for a lack of clear school regulations or team discontinuity. Implications for school policy and practice are discussed.
Constitutional mismatch repair deficiency: a case on a commonly misinterpreted mutation in colon cancer
Authors: C King , H Edwards , E Thompson , M Abdelmasseh , A Cuaranta , A Pacioles , J Sanabria 
Published: August 2024

AbstractIt is estimated that 153,020 cases of CRC per year, with an increase in diagnoses in younger patients. We present a case of a female with an early presentation of Lynch Syndrome and CRC, who, on her third malignant presentation, was re-diagnosed as a constitutional mismatch repair deficiency.
A social-ecological approach to support equitable land use decision-making
Authors: Brück Maria , Benra Felipe , Duguma Dula Wakassa , Fischer Joern , Jiren Tolera Senbeto , Law Elizabeth A. , Pacheco-Romero Manuel , Schultner Jannik , Abson David J. 
Published: August 2024

AbstractHuman-driven land use change can result in unequitable outcomes in the provision and appropriation of ecosystem services (ES). To better address equity-related effects of land use change in decision-making, analyses of land use and ES changes under different land use management alternatives should incorporate ecological and social information and take a disaggregated approach to ES analysis. Because such approaches are still scarce in the literature, we present a generalized social-ecological approach to support equitable land use decision-making (in terms of process and outcomes) and an example of its application to a case study in southwestern Ethiopia. We propose a six-step approach that combines scenario planning with equity-focused, disaggregated analyses of ES. Its application in our study area made equity-related effects of land use change explicit through the recognition of different beneficiary groups, value types, and spatial locations. We recommend the application of our approach in other contexts, especially in the Global South.
Emission trading in a high dimensional context: to what extent are carbon markets integrated with the broader system?
Authors: Quatrosi Marco 
Published: August 2024

AbstractThe EU ETS represents the cornerstone of the EU climate policy framework. While most of the studies focus on the determinants of carbon price, this work will provide further insights into the influence of European Emission Allowance (EUA) prices on carbon dioxide trends and variables of the economic-financial-climate-environmental system considering a large set of time series. Results highlighted how CO2 appears to be more influenced by commodity prices, climate variables, and past industrial performances. Furthermore, a shock in carbon prices could potentially exert significant turbulence on the carbon dioxide series, fading in intensity as time goes by. Overall, there appears to be a net positive effect on the influence of carbon prices on the system. However, robustness checks identified how the impact of carbon price on CO2 and other variables of the model is still weak. This work sheds light on the EU ETS's influence on a set of multidimensional variables. Still, overlapping national policies appear to interfere with the EU ETS effectiveness in the EU.
Analyzing the dynamics of forest fires in Málaga province: assessing the interplay of vegetation and human influence on regional hazard trends over three decades
Authors: Moreno María Teresa González , González José María Senciales 
Published: August 2024

AbstractWildfires are a global issue, exacerbated by climate change, and are particularly significant in the Mediterranean basin. This study aims to analyze forest fire dynamics in Málaga province (Southern Spain), examine their temporal evolution, evaluate significant hazards such as vegetation and human activities, and assess the effectiveness of measures taken against forest fires. The primary objective is to identify factors that exacerbate fires and suggest mitigation strategies. The study analyzed the frequency, affected area, and casualties of forest fires over the past 30 years using data from the Andalusian Environmental Information Network (REDIAM). Vegetation flammability, generally high in the province, was evaluated by classifying plant species from the Map of Land Use and Land Cover in Andalucía (MUCVA) and comparing burned and unburned areas from 2010 to 2022. Additionally, fuel density and continuity, also notably high, were examined using REDIAM geodata. The study also assessed the implementation of the Forest Fire Fighting Plan in the Autonomous Community of Andalucía (INFOCA Plan), focusing on its spatial distribution and the “protection” provided by public administration for areas with protective designations and public forests. Finally, the effectiveness of prevention and firefighting measures in Málaga province was evaluated through an extensive literature review. The data indicates a high occurrence of fires, with three-quarters caused by human activities, and significant peaks in the affected areas. It was found that protected areas represented three-quarters of the burned area. The findings revealed that certain preventive measures were insufficient, leading to proposed improvements.
Climate Imaginaries and the Linguistic Construction of Identities on Social Media
Authors: Schwegler Carolin , Landschoff Jöran , Rommel Leyla 
Published: August 2024

AbstractThis article takes a linguistic approach to the construction of group identities in relation to climate imaginaries, which condition what climate futures are considered possible. It employs social identity theory along with methods from Sociolinguistics and Discourse Linguistics to analyse patterns of positioning and stance-taking in social media discourse (Twitter/X, Instagram). By identifying typical multimodal practices at a micro level, as well as introducing five functional meta categories (›awareness, advice, and agitation‹, ›ritualised appreciation‹, ›solidarity and allyship, ›voice and advocacy‹, and ›community demarcation‹), the research investigates how digital discourse reflects and shapes group identities related to climate change topics. It thereby offers insights into the role of language in co-producing climate imaginaries in digitally shared environments.
A Scale-space Approach for Surface Normal Vector Estimation from Depth Maps
Authors: Ulucan Diclehan , Ulucan Oguzhan , Ebner Marc 
Published: August 2024

AbstractSurface normal vectors provide cues about the local geometric features of the scene which are utilized in many computer vision and computer graphics applications. Thus, the estimation of surface normals by utilizing structured range sensor data is an important research field. Thereupon, we propose a learning-free algorithm to estimate the surface normal vectors from depth maps. Our simple yet effective method relies on computations carried out in scale-space. Our main idea is to estimate the surface normals which cannot be properly computed in the finest scale from the coarser scales. Our method can estimate the surface normals even for images included in datasets that have challenging characteristics such as noisy real-world data or significantly large planar regions that either have a small or no gradient change. We analyze our algorithm’s performance by utilizing five benchmarks, namely, the MIT-Berkeley Intrinsic Images dataset, the New Tsukuba Dataset, the SceneNet RGB-D dataset, the IID-NORD dataset, and the NYU Depth Dataset V2, and by using two different evaluation strategies. According to the experimental results, our method can estimate surface normals efficiently without requiring neither complex computations nor huge amounts of data.
Radiocarbon dating of lipids preserved in pottery vessels: guidelines for best-practice in compound-specific 14C analyses
Authors: Casanova Emmanuelle , Knowles Timothy D J , Bayliss Alex , Evershed Richard P 
Published: August 2024

Abstract
Pottery vessels played a central role in the processing, storage and transport of animal and plant products by prehistoric and historic peoples with their chemical residues surviving for thousands of years. Accurate radiocarbon dating of archaeological pottery vessels by isolating reliable sources of carbon relating to the use of pots has long been a major challenge, but is now possible using compound-specific radiocarbon analysis of absorbed organic residues preserved in the ceramic fabric of the vessel wall. This method involves the radiocarbon dating of single fatty acids most commonly derived from degraded animal fats. These compounds are extracted from the ceramic matrix and isolated from potentially interfering compounds using preparative capillary gas chromatography. When coupled with lipid biomarker and compound-specific stable carbon isotope analyses, this method enables the palaeodietary and chronological information contained in archaeological lipids preserved in ceramic vessels to be interpreted together. From a practical perspective the methodology is challenging and for successful application must adhere to rigorous protocols. We present here guidelines which include (i) consideration of pottery selection, (ii) technical parameters for the isolation of fatty acids then their 14C dating and calibration, and (iii) case studies selected to illustrate the best use of this method.
Facile assembly of flexible, stretchable and attachable symmetric microsupercapacitors with wide working voltage windows and favorable durability
Authors: Han Xiangguang , Wu Xiaoyu , Zhao Libo , Li Min , Jia Chen , Li Zhikang , Xie Jiaqi , Luo Guoxi , Yang Ping , Boukherroub Rabah , Türker Yurdanur , Özkaynak Mert Umut , Dönmez Koray Bahadır 
Published: August 2024

AbstractWith the increasing development of intelligent robots and wearable electronics, the demand for high-performance flexible energy storage devices is drastically increasing. In this study, flexible symmetric microsupercapacitors (MSCs) that could operate in a wide working voltage window were developed by combining laser-direct-writing graphene (LG) electrodes with a phosphoric acid-nonionic surfactant liquid crystal (PA-NI LC) gel electrolyte. To increase the flexibility and enhance the conformal ability of the MSC devices to anisotropic surfaces, after the interdigitated LG formed on the polyimide (PI) film surface, the devices were further transferred onto a flexible, stretchable and transparent polydimethylsiloxane (PDMS) substrate; this substrate displayed favorable flexibility and mechanical characteristics in the bending test. Furthermore, the electrochemical performances of the symmetric MSCs with various electrode widths (300, 400, 500 and 600 μm) were evaluated. The findings revealed that symmetric MSC devices could operate in a large voltage range (0–1.5 V); additionally, the device with a 300 μm electrode width (MSC-300) exhibited the largest areal capacitance of 2.3 mF cm−2 at 0.07 mA cm−2 and an areal (volumetric) energy density of 0.72 μWh cm−2 (0.36 mWh cm−3) at 55.07 μW cm−2 (27.54 mW cm−3), along with favorable mechanical and cycling stability. After charging for ~20 s, two MSC-300 devices connected in series could supply energy to a calculator to operate for ~130 s, showing its practical application potential as an energy storage device. Moreover, the device displayed favorable reversibility, stability and durability. After 12 months of aging in air at room temperature, its electrochemical performance was not altered, and after charging-discharging measurements for 5000 cycles at 0.07 mA cm−2, ~93.6% of the areal capacitance was still retained; these results demonstrated its practical long-term application potential as an energy storage device.
The diagnosis of ASD with MRI: a systematic review and meta-analysis
Authors: Schielen Sjir J. C. , Pilmeyer Jesper , Aldenkamp Albert P. , Zinger Svitlana 
Published: August 2024

AbstractWhile diagnosing autism spectrum disorder (ASD) based on an objective test is desired, the current diagnostic practice involves observation-based criteria. This study is a systematic review and meta-analysis of studies that aim to diagnose ASD using magnetic resonance imaging (MRI). The main objective is to describe the state of the art of diagnosing ASD using MRI in terms of performance metrics and interpretation. Furthermore, subgroups, including different MRI modalities and statistical heterogeneity, are analyzed. Studies that dichotomously diagnose individuals with ASD and healthy controls by analyses progressing from magnetic resonance imaging obtained in a resting state were systematically selected by two independent reviewers. Studies were sought on Web of Science and PubMed, which were last accessed on February 24, 2023. The included studies were assessed on quality and risk of bias using the revised Quality Assessment of Diagnostic Accuracy Studies tool. A bivariate random-effects model was used for syntheses. One hundred and thirty-four studies were included comprising 159 eligible experiments. Despite the overlap in the studied samples, an estimated 4982 unique participants consisting of 2439 individuals with ASD and 2543 healthy controls were included. The pooled summary estimates of diagnostic performance are 76.0% sensitivity (95% CI 74.1–77.8), 75.7% specificity (95% CI 74.0–77.4), and an area under curve of 0.823, but uncertainty in the study assessments limits confidence. The main limitations are heterogeneity and uncertainty about the generalization of diagnostic performance. Therefore, comparisons between subgroups were considered inappropriate. Despite the current limitations, methods progressing from MRI approach the diagnostic performance needed for clinical practice. The state of the art has obstacles but shows potential for future clinical application.
A cross-over, randomised feasibility study of digitally-printed versus hand-painted artificial eyes in adults: PERSONAL-EYE-S
Authors: Woodward Amie , Coleman Elizabeth , Ronaldson Sarah , Zoltie Tim , Bartlett Paul , Wilson Laura , Archer Tom , Kawalek Jessica , Boele Florien , Chang Bernard , Kalantzis George , Theaker Mike , El-Hindy Nabil , Walshaw Emma , Gout Taras , Watson Judith 
Published: August 2024

Abstract
Background/objectives
Over 60,000 patients in the United Kingdom are estimated to have artificial eyes. Manufacturing and hand-painting of artificial eyes have not changed significantly since 1948. Delays and colour-matching issues may severely impact a patient’s rehabilitation pathway. Technology advances mean alternatives are now possible. This cross-over, randomised feasibility trial aimed to determine the feasibility of conducting a full-scale trial of the effectiveness and cost-effectiveness of digitally-printed artificial eyes compared to hand-painted.

Subjects/methods
Patients aged ≥18 years who were longstanding artificial eye users requiring a replacement were randomised to receive either a hand-painted or digitally-printed eye first followed by the other type of eye. Participants were asked to approach a close contact (CC) willing to participate alongside them. A subset of participants, their CCs, and staff were interviewed about their opinions on trial procedures, artificial eyes, delivery times and satisfaction.

Results
Thirty-five participants were randomised and 10 CCs consented. Participant retention at final follow-up was 85.7%. Outcome data completion rates ranged from 91–100%. EQ-5D-5L completion ranged from 83–97%. Resource-use completion ranged from 0–94% with total costs at £347 for hand-painted and £404 for digitally-printed eye. There were two adverse events. Twelve participants, five CCs, and five staff were interviewed. There were positive and negative features of both types of eyes. We identified that social and psychological wellbeing is affected, often for many years after eye removal. Participation in the feasibility study was well accepted.

Conclusions
The feasibility study outcomes indicate that a full trial is achievable.

Trial registration number
ISRCTN85921622.
Detection of differentially methylated CpGs between tumour and adjacent benign cells in diagnostic prostate cancer samples
Authors: FitzGerald Liesel M. , Jung Chol-hee , Wong Ee Ming , Joo JiHoon E. , Bassett Julie K. , Dowty James G. , Wang Xiaoyu , Dai James Y. , Stanford Janet L. , O’Callaghan Neil , Nottle Tim , Pedersen John , Giles Graham G. , Southey Melissa C. 
Published: August 2024

AbstractDifferentially methylated CpG sites (dmCpGs) that distinguish prostate tumour from adjacent benign tissue could aid in the diagnosis and prognosis of prostate cancer. Previously, the identification of such dmCpGs has only been undertaken in radical prostatectomy (RP) samples and not primary diagnostic tumour samples (needle biopsy or transurethral resection of the prostate). We interrogated an Australian dataset comprising 125 tumour and 43 adjacent histologically benign diagnostic tissue samples, including 41 paired samples, using the Infinium Human Methylation450 BeadChip. Regression analyses of paired tumour and adjacent benign samples identified 2,386 significant dmCpGs (Bonferroni p < 0.01; delta-β ≥ 40%), with LASSO regression selecting 16 dmCpGs that distinguished tumour samples in the full Australian diagnostic dataset (AUC = 0.99). Results were validated in independent North American (npaired = 19; AUC = 0.87) and The Cancer Genome Atlas (TCGA; npaired = 50; AUC = 0.94) RP datasets. Two of the 16 dmCpGs were in genes that were significantly down-regulated in Australian tumour samples (Bonferroni p < 0.01; GSTM2 and PRKCB). Ten additional dmCpGs distinguished low (n = 34) and high Gleason (n = 88) score tumours in the diagnostic Australian dataset (AUC = 0.95), but these performed poorly when applied to the RP datasets (North American: AUC = 0.66; TCGA: AUC = 0.62). The DNA methylation marks identified here could augment and improve current diagnostic tests and/or form the basis of future prognostic tests.