bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: An Organocatalytic Approach to Stereoselective Synthesis of 2‐Hydroxyazetidines and 2‐Hydroxypyrrolidines.
Authors: Rai Ankita , Yadav Lal Dhar S. 
Published: September 2013

AbstractChiral enamines derived from aldehydes and PRS undergo Mannich‐type reaction with imines and aziridines followed by intramolecular hemiaminalization to afford the title heterocycles with complete diastereoselectivity.
ChemInform Abstract: P‐Spiro Phosphonium Salts Catalyzed Asymmetric Fluorination of 3‐Substituted Benzofuran‐2(3H)‐ones.
Authors: Zhu Chuan‐Le , Fu Xiao‐Yun , Wei Ai‐Jia , Cahard Dominique , Ma Jun‐An 
Published: September 2013

AbstractThe (S,S)‐isomer of the depicted phosphonium salt is capable of catalyzing the title reaction with excellent yields and low to moderate enantioselectivities.
ChemInform Abstract: An Efficient Synthesis of β,γ,γ‐Trisubstituted‐α‐diethoxyphosphoryl‐γ ‐lactams: A Convenient Approach to α‐Methylene‐γ‐lactams.
Authors: Deredas Dariusz , Albrecht Lukasz , Krawczyk Henryk 
Published: September 2013

AbstractThe synthesis of title compounds (III) is achieved in a single step through tetramethylguanidine‐promoted Michael addition of malonate (II) to acrylates (I) followed by spontaneous lactamization and acylation.
ChemInform Abstract: Symmetric and Unsymmetric 3,3′‐Linked Bispyrroles via Ring‐Enlargement Reactions of Furan‐Derived Donor—Acceptor Cyclopropanes.
Authors: Kaschel Johannes , Schneider Tobias F. , Kratzert Daniel , Stalke Dietmar , Werz Daniel B. 
Published: September 2013

AbstractA synthetic route has been developed to access symmetrically and unsymmetrically substituted 3,3′‐linked bispyrroles by making use of the special features of furan‐derived donor‐acceptor cyclopropanes.
ChemInform Abstract: Three‐Component Synthesis of Poly‐Substituted Tetrahydroindoles Through p‐TsOH Promoted Alkoxylation.
Authors: Shi Qing‐Qing , Fu Li‐Ping , Shi Yu , Ding Hua‐Qin , Luo Jing‐Hua , Jiang Bo , Tu Shu‐Jiang 
Published: September 2013

AbstractOptimized conditions allow a sequential alkoxylation/heterocyclization of arylglyoxal monohydrates, alcohols and enaminones to produce the title species in a short reaction time.
ChemInform Abstract: Synthesis and Anticancer Activity of New Substituted Pyrazoles and Their Derived 1,2,4‐Triazoles and Sugar Derivatives.
Authors: Flefel Eman M. , Tantawy Waled A. , El‐Sayed Wael A. , Sayed Hayam H. , Fathy Nahed M. 
Published: September 2013

AbstractVarious title compounds are prepared and tested for their antitumor activities.
ChemInform Abstract: Synthesis of Substituted Hydantoins in Low Melting Mixtures.
Authors: Gore Sangram , Chinthapally Kiran , Baskaran Sundarababu , Koenig Burkhard 
Published: September 2013

AbstractUnsaturated ketoacids (I) are readily converted into functionalized hydantoins (III) in a low melting mixture of N,N′‐dimethylurea and L‐tartaric acid.
ChemInform Abstract: Synthesis and Properties of 1‐(2‐(Alkylamino)‐2‐oxoethyl) Pyridinium Chloride Surfactants.
Authors: Wang Li‐yan , Qin Hong‐lei , Wang Lei , Huo Shi‐chao , Zhao Bing , Song Bo , Yan Tie 
Published: September 2013

AbstractThe synthesized surfactants (V) show good antibacterial activities against sulfate‐reducing bacteria, metatrophic bacteria and iron bacteria in oil field injection water.
ChemInform Abstract: Regiospecific 6‐endo‐Annulation of in situ Generated 3,4‐Dienamides/Acids: Synthesis of δ‐Lactams and δ‐Lactones.
Authors: Liu Ying , Barry Badru‐Deen , Yu Haifeng , Liu Jianquan , Liao Peiqiu , Bi Xihe 
Published: September 2013

AbstractA novel and efficient method for the construction of α‐(1,3‐dithiolan‐2‐ylidene) δ‐lactams (III) and δ‐lactones (V) is developed.
ChemInform Abstract: A Highly Efficient and Selective Aerobic Cross‐Dehydrogenative‐Coupling Reaction Photocatalyzed by a Platinum(II) Terpyridyl Complex.
Authors: Zhong Jian‐Ji , Meng Qing‐Yuan , Wang Ge‐Xia , Liu Qiang , Chen Bin , Feng Ke , Tung Chen‐Ho , Wu Li‐Zhu 
Published: September 2013

AbstractThe title reaction affords the desired coupling products within a short reaction time under ambient air conditions.
ChemInform Abstract: A Green Synthesis of Quinoxalines and 2,3‐Dihydropyrazines.
Authors: Delpivo Camilla , Micheletti Gabriele , Boga Carla 
Published: September 2013

AbstractVarious 1,2‐diamines react with 1,2‐dicarbonyl compounds in water in the absence of any catalyst to give the desired heterocyclic systems.
ChemInform Abstract: Electrophilic Cyclization of N‐Alkynyl‐2‐(organochalcogen)imidazoles: An Alternative Access to Imidazo[2,1‐b]chalcogenazoles.
Authors: Grimaldi Tamiris B. , Godoi Benhur , Roehrs Juliano A. , Speranca Adriane , Zeni Gilson 
Published: September 2013

AbstractAn electrophilic title cyclization reaction allows the selective synthesis of 3‐iodoimidazoselenazoles [cf.
ChemInform Abstract: Reaction of Selenium Dichloride with Acrylic Acid and Its Derivatives. Regioselective Synthesis of New Functionalized Selenides.
Authors: Potapov V. A. , Khabibulina A. G. , Albanov A. I. , Amosova S. V. 
Published: September 2013

AbstractThe reaction of selenium dichloride, which can be prepared in situ from selenium and sulfuryl chloride, with acrylic acid (IIa), ethyl acrylate (IIb), or acrylonitrile at ‐20°C gives the corresponding selenides (II) in high yields.
ChemInform Abstract: Study on Synthesis of 2‐(Substituted benzylidene) amino‐2‐deoxy‐1,3,4,6‐tetra‐O‐acetyl‐β‐D‐glucopyranones from D‐Glucosamine.
Authors: Nguyen Dinh Thanh , Nguyen Van Quoc 
Published: September 2013

AbstractThe title compounds (III) are obtained in reactions of α‐D‐glucosamine hydrochloride with different substituted benzaldehydes under optimized reaction conditions.
ChemInform Abstract: Cytotoxic Azaphilone Alkaloids from Chaetomium globosum TY1.
Authors: Li Xiang , Tian Ye , Yang Sheng‐xiang , Zhang Ya‐mei , Qin Jian‐chun 
Published: September 2013

AbstractThree novel azaphilone alkaloids, chaetomugilides A—C, are isolated together with three related compounds.
ChemInform Abstract: Facile Syntheses of Novel Salts of a Triazole Antifungal Agent with Enhanced Solubility.
Authors: Kumar Neeraj , Shishu Shishu , Kapoor Rishi 
Published: September 2013

AbstractNitric, sulfuric, and p‐toluenesulfonic acid addition salts of itraconazole are prepared to enhance the aqueous solubility and dissolution characteristics of the drug.
ChemInform Abstract: Crystallographic and Structural Characterization of Heterometallic Platinum Compounds. Part 2. Heterobinuclear Pt Compounds with Pt···M (M: Transition or Lanthanide Metal) < 3.0 Å
Authors: Melnik Milan , Sprusansky Ondrej , Holloway Clive E. 
Published: September 2013

AbstractReview: 192 refs.
ChemInform Abstract: Transition Metal‐Catalyzed Efficient and Green Transformations of P(O)‐H Compounds to Functional Organophosphorus Compounds
Authors: Xu Qing , Zhou Yong‐Bo , Zhao Chang‐Qiu , Yin Shuang‐Feng , Han Li‐Biao 
Published: September 2013

AbstractReview: 105 refs.
Calibration of the X‐Ray Photoelectron Spectroscopy Binding Energy Scale for the Characterization of Heterogeneous Catalysts: Is Everything Really under Control?
Authors: Jacquemin Marc , Genet Michel J. , Gaigneaux Eric M. , Debecker Damien P. 
Published: September 2013

AbstractInvestigations of X‐ray photoelectron spectra from solid samples need corrections for the surface charging effect. For powder samples such as heterogeneous catalysts and their supports, the C(C,H) component of the C 1s peak is often used as an internal standard for the calibration of the binding energy scale. Although this method is widely recognized as suitable for the study of heterogeneous catalysts, we show that a significant calibration bias can be encountered upon comparing samples with different bulk composition. In this paper, a series of SiO2–Al2O3 supports and Pd/SiO2–Al2O3 catalysts with various Si/Al ratios were studied. The spectra issued from these samples were processed with the classical calibration method on the basis of the carbon peak. Important discrepancies in the relative position of the photoelectron peaks were noticed. After systematically discarding instrument‐related issues, a true chemical influence of the bulk matrix on the analyzed surface species was evidenced. The extent of this chemical effect was dependent on the composition of the sample and more precisely on its ionicity. Two possible mechanisms for this chemical effect were proposed and discussed. Finally, an alternative calibration method was offered.
Durable Superhydrophobic Surfaces Prepared by Spray Coating of Polymerized Organosilane/Attapulgite Nanocomposites
Authors: Li Bucheng , Zhang Junping , Wu Lei , Wang Aiqin 
Published: September 2013

AbstractComplicated and expensive preparation methods and the low stability of most superhydrophobic surfaces are the bottlenecks that must be faced for their practical application. Herein, a simple and low‐cost approach for preparing durable superhydrophobic surfaces by spray coating of polymerized organosilane/attapulgite (POS/APT) nanocomposites is reported. The POS/APT nanocomposites were prepared by condensation of hexadecyltriethoxysilane and tetraethoxysilane in the presence of APT through a modified Stöber method. The morphology and content of clay minerals have great influence on the superhydrophobicity. Only rodlike APT with a weight ratio of APT to organosilanes not less than 0.60 can form the superhydrophobic surfaces. The POS/APT superhydrophobic surfaces feature high water contact angle (CA≈160°), low sliding angle (SA≈2°), excellent stability, and good transparency. A spray coating density as low as 5 g m−2 is enough to obtain the superhydrophobic properties. The cost of such a coating is approximately 4 RMB m−2. The POS/APT surfaces are stable towards sand abrasion, water pressure, harsh temperature, UV irradiation, and solvent immersion. In addition, a slightly damaged surface can be readily repaired by spray coating again according to the same procedure. Moreover, the durable POS/APT superhydrophobic coatings are applicable to various substrates (e.g., polyurethane plate, paper, and polyester textile) and can be easily scaled up.
Modular Synthesis of Optically Active Tröger’s Base Analogues
Authors: Kamiyama Takuya , Özer Merve Sinem , Otth Elisabeth , Deska Jan , Cvengroš Ján 
Published: September 2013

AbstractFor the first time, enantioselective catalysis was applied for the preparation of Tröger’s base derivatives affording N‐stereogenic building blocks not only in excellent enantiomeric purity but also in an easily scalable fashion. Enzymatic kinetic resolution proved efficient to yield functionalized Tröger’s bases, which can be subsequently modified by various chemical methods without any erosion of stereogenic information. In concert with a preparatively convenient protocol for the synthesis of the racemic substrates from commercially available anilines, a highly practicable and flexible route towards a wide range of enantiopure Tröger’s base analogues is provided.
Manganese‐Catalyzed Selective Oxidation of Aliphatic CH groups and Secondary Alcohols to Ketones with Hydrogen Peroxide
Authors: Dong Jia Jia , Unjaroen Duenpen , Mecozzi Francesco , Harvey Emma C. , Saisaha Pattama , Pijper Dirk , de Boer Johannes W. , Alsters Paul , Feringa Ben L. , Browne Wesley R. 
Published: September 2013

AbstractAn efficient and simple method for selective oxidation of secondary alcohols and oxidation of alkanes to ketones is reported. An in situ prepared catalyst is employed based on manganese(II) salts, pyridine‐2‐carboxylic acid, and butanedione, which provides good‐to‐excellent conversions and yields with high turnover numbers (up to 10 000) with H2O2 as oxidant at ambient temperatures. In substrates bearing multiple alcohol groups, secondary alcohols are converted to ketones selectively and, in general, benzyl CH oxidation proceeds in preference to aliphatic CH oxidation.
Does polyomavirus infection interfere with bladder cancer fluorescence in situ hybridization?
Authors: Hossain Deloar , Hull David , Kalantarpour Fatemeh , Maitlen Rebecca , Qian Junqi , Bostwick David G. 
Published: September 2013

Urine cytology is a proven and widely used screening tool for the detection of urothelial carcinoma. However, morphologic features of polyomavirus infected cells, characterized by nuclear inclusions (decoy cells) are a known source of diagnostic confusion with malignancy. Fluorescence in situ hybridization (FISH) is now routinely used to support the cytological diagnosis of urothelial carcinoma and monitor for recurrence. We sought to determine whether polyomavirus infection could result in positive FISH results (aneuploidy).This study deals with retrospective study of 100 polyomavirus‐infected urine samples from patients with no history of urothelial carcinoma or organ transplantation. All cases were stained with Papanicolaou and acid hematoxylin stain. One slide from each sample was de‐stained and FISH was performed using chromosome enumeration probes 3, 7, 17, and locus‐specific probe 9p21.Adequate cells for FISH analysis (25 cells) were present in 81 cases; 19 cases were insufficient due to loss of cells during de‐staining and FISH preparation process. All polyomavirus‐infected cells (decoy cells) exhibited a normal chromosome pattern. Four cases were FISH positive, but there were no positive decoy cells.Decoy cells did not exhibit aneuploidy by FISH. The presence of decoy cells does not exclude the possibility of concurrent urothelial carcinoma. Acid hematoxylin stain appeared to supplement the Papanicolou stain in identifying and confirming the presence of polyomavirus infection. Diagn. Cytopathol. 2014;42:225–229. © 2013 Wiley Periodicals, Inc.
Weight bias among professionals treating eating disorders: Attitudes about treatment and perceived patient outcomes
Authors: Puhl Rebecca M. , Latner Janet D. , King Kelly M. , Luedicke Joerg 
Published: September 2013

ABSTRACTObjectiveThis study aimed to assess weight bias among professionals who specialize in treating eating disorders and identify to what extent their weight biases are associated with attitudes about treating obese patients.MethodParticipants were 329 professionals treating eating disorders, recruited through professional organizations that specialize in eating disorders. Participants completed anonymous, online self‐report questionnaires, assessing their explicit weight bias, perceived causes of obesity, attitudes toward treating obese patients, perceptions of treatment compliance and success of obese patients, and perceptions of weight bias among other practitioners.ResultsNegative weight stereotypes were present among some professionals treating eating disorders. Although professionals felt confident (289; 88%) and prepared (276; 84%) to provide treatment to obese patients, the majority (184; 56%) had observed other professionals in their field making negative comments about obese patients, 42% (138) believed that practitioners who treat eating disorders often have negative stereotypes about obese patients, 35% (115) indicated that practitioners feel uncomfortable caring for obese patients, and 29% (95) reported that their colleagues have negative attitudes toward obese patients. Compared to professionals with less weight bias, professionals with stronger weight bias were more likely to attribute obesity to behavioral causes, expressed more negative attitudes and frustrations about treating obese patients, and perceived poorer treatment outcomes for these patients.DiscussionSimilar to other health disciplines, professionals treating eating disorders are not immune to weight bias. This has important implications for provision of clinical treatment with obese individuals and efforts to reduce weight bias in the eating disorders field. © 2013 Wiley Periodicals, Inc. (Int J Eat Disord 2014; 47:65–75)
Metal‐Free Directed ortho C–H Iodination: Synthesis of 2′‐Iodobiaryl‐2‐carbonitriles
Authors: Sarkar Satinath , Jana Manoranjan , Narender Tadigoppula 
Published: September 2013

AbstractMetal‐free directed ortho C–H iodination of biaryl‐2‐carbonitriles was developed. A series of 2′‐iodobiaryl‐2‐carbonitriles were synthesized from substituted biphenylcarbonitriles and naphthylbenzonitriles in reasonably good yields by using bis(pyridine)iodonium(I) tetrafluoroborate (IPy2BF4, Barluenga's reagent) and HBF4·OEt2. The biaryl‐2‐carbonitriles are useful precursors for the synthesis of benzocyclic ketones.
Gallium(III) Triflate Catalyzed Diastereoselective Mukaiyama Aldol Reaction by Using Low Catalyst Loadings
Authors: Plancq Baptiste , Justafort Lyse Carole , Lafantaisie Mathieu , Ollevier Thierry 
Published: September 2013

AbstractA mild method for the diastereoselective Mukaiyama aldol reaction is reported. By using a low loading of the gallium(III) triflate catalyst (down to 0.01 mol‐%), the transformation proceeds efficiently to afford the corresponding β‐hydroxy ketones in yields up to 92 %. To the best of our knowledge, this is the first report of a metal triflate acting as a safe, bench‐stable, and slow‐releasing source of triflic acid for the Mukaiyama aldol reaction.
Electrochemical Sensing of Catecholamines at the Water/ 1,6‐Dichlorohexane Interface
Authors: Ribeiro José A. , Silva F. , Pereira Carlos M. 
Published: September 2013

AbstractIn this work, the analytical use of facilitated ion transfer of catecholamines by dibenzo‐18‐crown‐6 was investigated at the water/1,6‐dichlorohexane interface using electrochemical methods (cyclic and square wave voltammetry). The experimental conditions for the analytical determination of noradrenaline and dopamine were established and detection limits of 1.7 and 0.35 µM were obtained, respectively. The effect of excess ascorbic acid on the transfer and detection of the two catecholamines was investigated. The selectivity coefficients obtained for dopamine and noradrenaline in the presence of ascorbic acid were 3.5×10−4 and 2.5×10−3, respectively.
Systematic administration of B vitamins attenuates neuropathic hyperalgesia and reduces spinal neuron injury following temporary spinal cord ischaemia in rats
Authors: Yu C.‐Z. , Liu Y.‐P. , Liu S. , Yan M. , Hu S.‐J. , Song X.‐J. 
Published: September 2013

AbstractBackgroundB vitamins have been demonstrated to be effective in treating chronic pain due to peripheral nerve injury. We investigated whether B vitamins could alleviate neuropathic pain and reduce neuron injury following temporary ischaemia in a rat model of spinal cord ischaemia‐reperfusion injury (SCII).MethodsSCII was produced by transiently blocking the unilateral lumbar arteries in adult male Sprague‐Dawley rats. Behavioural and neurochemical signs of neuropathic pain and spinal neuron injury were analysed with and without B vitamin treatment.ResultsSCII caused behavioural thermal hyperalgesia and mechanical allodynia and neurochemical alterations, including increased expression of the vanilloid receptor 1 (VR1) and induction of c‐Fos, as well as activation of the astrocytes and microglial cells in the spinal cord. Repetitive systemic administration of vitamin B complex (B1/B6/B12 at 33/33/0.5 mg/kg, i.p., daily, for 7–14 consecutive days) significantly reduced thermal hyperalgesia and the increased expression of VR1 and c‐Fos, as well as activation of the astrocytes and microglial cells. SCII caused a dramatic decrease of the expression of the rate‐limiting enzyme glutamic acid decarboxylase‐65 (GAD65), which synthesizes γ‐aminobutyric acid (GABA) in the axonal terminals, and β‐III‐tubulin, and also caused loss of Nissl bodies in the spinal cord. These alterations were largely prevented and rescued by the B vitamin treatment.ConclusionsThese findings support the idea that the B vitamins are capable of neuroprotection and antinociception during spinal cord injury due to temporary ischaemia. Rescuing the loss of inhibitory GABAergic tone may reduce spinal central sensitization and contribute to B vitamin‐induced analgesia.
Microcystins in potable surface waters: toxic effects and removal strategies
Authors: Roegner Amber F. , Brena Beatriz , González‐Sapienza Gualberto , Puschner Birgit 
Published: September 2013

ABSTRACTIn freshwater, harmful cyanobacterial blooms threaten to increase with global climate change and eutrophication of surface waters. In addition to the burden and necessity of removal of algal material during water treatment processes, bloom‐forming cyanobacteria can produce a class of remarkably stable toxins, microcystins, difficult to remove from drinking water sources. A number of animal intoxications over the past 20 years have served as sentinels for widespread risk presented by microcystins. Cyanobacterial blooms have the potential to threaten severely both public health and the regional economy of affected communities, particularly those with limited infrastructure or resources. Our main objectives were to assess whether existing water treatment infrastructure provides sufficient protection against microcystin exposure, identify available options feasible to implement in resource‐limited communities in bloom scenarios and to identify strategies for improved solutions. Finally, interventions at the watershed level aimed at bloom prevention and risk reduction for entry into potable water sources were outlined. We evaluated primary studies, reviews and reports for treatment options for microcystins in surface waters, potable water sources and treatment plants. Because of the difficulty of removal of microcystins, prevention is ideal; once in the public water supply, the coarse removal of cyanobacterial cells combined with secondary carbon filtration of dissolved toxins currently provides the greatest potential for protection of public health. Options for point of use filtration must be optimized to provide affordable and adequate protection for affected communities. Copyright © 2013 John Wiley & Sons, Ltd.
Catabolism of Host‐Derived Compounds During Extracellular Bacterial Infections
Authors: Meadows Jamie A. , Wargo Matthew J. 
Published: September 2013

ABSTRACTEfficient catabolism of host‐derived compounds is essential for bacterial survival and virulence. While these links in intracellular bacteria are well studied, such studies in extracellular bacteria lag behind, mostly for technical reasons. The field has identified important metabolic pathways, but the mechanisms by which they impact infection and in particular, establishing the importance of a compound's catabolism versus alternate metabolic roles has been difficult. In this review we will examine evidence for catabolism during extracellular bacterial infections in animals and known or potential roles in virulence. In the process, we point out key gaps in the field that will require new or newly adapted techniques. J. Cell. Biochem. 115: 217–223, 2014. © 2013 Wiley Periodicals, Inc.