bluuebunny/crossref_metadata_2025_split huggingface dataset:
Designing SNAKES AND LADDERS
Authors: Hodkiewicz Melinda 
Published: July 2015

Background. Asset Management improvement initiatives often fail to deliver the intended value. Poorly developed strategy contributes to these failures. Aim. To assist managers in developing skills in Asset Management (AM) strategy in order to meet the requirements set out in the new ISO 55001 Asset Management Standard. Method. Managers develop the layout for a SNAKES AND LADDERS (S&L) game board. This involves managers deciding what strategic activities to pursue (ladders) and where to place them on the board. Other considerations include the sequence of the ladders and their length, where the length is a proxy for impact of the activity. Managers also need to identify what risks (snakes) are associated with each activity and what impact they have (the length of the snake). Results. The board development process helps managers to identify factors crucial to effective strategy development such as limiting the number of activities, sequencing these activities over an appropriate time scale, assessing risks of each activities and the consequence of risks being realized on subsequent activities. Conclusion. The S&L training is an accessible and time-efficient way to get managers to engage with each other and with crucial concepts in strategy development in the asset management context.
Short-Term Outcomes of Management of Endovascular Aneurysm Repair in Patients With Dilated Iliacs
Authors: Stather P. W. , Rhema I. A. , Sidloff D. A. , Sayers R. D. , Bown M. J. , Choke E. 
Published: July 2015

Objectives: This study aims to evaluate outcomes following endovascular aneurysm repair (EVAR) in patients with dilated but not aneurysmal common iliac arteries. Methods: Data prospectively collected from 342 elective EVARs were analyzed retrospectively. Dilated common iliac anatomy was defined as 21 to 24 mm. Patients with iliac aneurysms or external iliac artery (EIA) extension were excluded. Patients were followed up using clinical review, plain radiographs, duplex imaging, and selective computed tomography scanning. Results: Median age was 75 years with a mean follow-up of 3.6 years. In all, 33 patients had dilated common iliac arteries (DCIAs) and 309 had non-dilated common iliac arteries (NDCIA). There was no difference in aneurysm diameter or neck characteristics (length, diameter, angulation, thrombus, and flare) between the subgroups. There was no significant difference in technical success, 30-day mortality, late mortality, aneurysm-related mortality, 30-day reinterventions, stent graft migration, limb occlusion, sac expansion, graft rupture, type 1 endoleaks, type 3 endoleaks, and total reinterventions (all Ps > .05). There was a significant decrease in type II endoleaks in patients with DCIA compared to NDCIA (NDCIA 12.9% and DCIA 0.0%; P = .02). Conclusion: Patients presenting with abdominal aortic aneurysms with DCIA can be successfully treated with EVAR with no increase in complications without extension into the EIA.
Malignant ascites in patients with terminal cancer is effectively treated with permanent peritoneal catheter
Authors: Meier Michelle , Mortensen Frank V. , Madsen Hans Henrik Torp 
Published: July 2015

Background Malignant ascites is a pathological condition caused by intra- or extra-abdominal disseminated cancer. The object of treatment is palliation. In search of an effective and minimally invasive palliative treatment of malignant ascites placement of a permanent intra peritoneal catheter has been suggested. Purpose To evaluate our experiences with treatment of malignant ascites by implantation of a permanent PleurX catheter. Material and Methods A retrospective study was conducted, comprising 20 consecutive patients with terminal cancer, who had a permanent PleurX catheter implanted because of malignant ascites in the period from February to November 2014. Using the patients’ medical records, we retrieved data on patients and procedures. Results The technical success rate was 100%. Catheter patency was 95.2%, one catheter was removed due to dislocation. Ten patients (50.0%) experienced minor adverse events. No procedural difficulties were reported and there was no need for additional treatment of malignant ascites after catheter implantation. Median residual survival after catheter implantation was 27 days. Conclusion Implantation of a permanent PleurX catheter is a minimally invasive and effective procedure with only minor adverse events and a high rate of catheter patency in patients with malignant ascites caused by terminal cancer disease.
Silibinin down-regulates FAT10 and modulate TNF-α/IFN-γ-induced chromosomal instability and apoptosis sensitivity
Authors: Gao Yun , Theng Steven Setiawan , Mah Way-Champ , Lee Caroline G. L. 
Published: July 2015

ABSTRACT
Pleiotropic pro-inflammatory cytokines, TNF-α and IFN-γ (TI), play important yet diverse roles in cell survival, proliferation, and death. Recent evidence highlights FAT10 as a downstream molecule in the pathway of inflammation-induced tumorigenesis through mediating the effect of cytokines in causing numerical CIN and protecting cells from cytokines-induced cell death. cDNA microarray analysis of cells treated with TI revealed 493 deregulated genes with FAT10 being the most up-regulated (85.7-fold) gene and NF-κB being the key nodal hub of TI-response genes. Silibinin is reported to be a powerful antioxidant and has anti-C effects against various carcinomas by affecting various signaling molecules/pathways including MAPK, NF-κB and STATs. As NF-κB signaling pathway is a major mediator of the tumor-promoting activities of TI, we thus examine the effects of silibinin on TI-induced FAT10 expression and CIN. Our data showed that silibinin inhibited expression of FAT10, TI-induced chromosome instability (CIN) as well as sensitizes cells to TI-induced apoptosis. Significantly, silibinin suppressed intra-tumorally injected TNF-α-induced tumor growth. This represents the first report associating silibinin with FAT10 and demonstrating that silibinin can modulate TI-induced CIN, apoptosis sensitivity and suppressing TNF-α-induced tumor growth.
Region and dynamic specificities of adult neural stem cells and oligodendrocyte precursors in myelin regeneration in the mouse brain
Authors: Brousse Béatrice , Magalon Karine , Durbec Pascale , Cayre Myriam 
Published: July 2015

ABSTRACT
Myelin regeneration can occur in the brain following demyelination. Parenchymal oligodendrocyte progenitors (pOPC) are known to play a crucial role in this process. Neural stem cells (NSC) residing in the ventricular-subventricular zone (V-SVZ) also have the ability to generate oligodendrocytes but their contribution to endogenous myelin repair was so far considered to be negligible. Here, we addressed the relative contribution of pOPC and V-SVZ-derived neural progenitors (SVZdNP) to remyelination in cuprizone mouse models of acute or chronic corpus callosum (CC) demyelination. Using genetic tracing, we uncover an unexpected massive and precocious recruitment of SVZdNP in the anterior CC after acute demyelination. These cells very quickly adopt an oligodendrocytic fate and robustly generate myelinating cells as efficiently as pOPC do. In more posterior areas of the CC, SVZdNP recruitment is less important whereas pOPC contribute more, underlining a regionalization in the mobilization of these two cell populations. Strikingly, in a chronic model when demyelination insult is sustained in time, SVZdNP minimally contribute to myelin repair, a failure associated with a depletion of NSC and a drastic drop of progenitor cell proliferation in V-SVZ. In this context, pOPC remain reactive, and become the main contributors to myelin regeneration. Altogether our results highlight a region and context-dependent contribution of SVZdNP to myelin repair that can equal pOPC. They also raise the question of a possible exhaustion of V-SVZ proliferation potential in chronic pathologies.
Synthesis and Properties of New Liquid Crystalline Organogelators with a Tris[4-(benzoylamino)phenyl]amine Core
Authors: Kubo Kanji , Moriyama Yuichiro , Ujiie Seiji , Mori Akira 
Published: July 2015

Abstract
As a new liquid crystalline organogelator, tris[4-(benzoylamino)phenyl]amine derivatives were synthesized. Tris[4-(benzoylamino)phenyl]amine derivatives with six or nine alkoxy groups exhibited an enantiotropic hexagonal columnar phase. Furthermore tris[4-(benzoylamino)phenyl]amine derivatives gelled organic liquids such as n-hexane, decane, hexadecene, ethanol, 1-hexanol, 1-decanol, chloroform, toluene, salad oil, limonene, linalool, nerol, citronellol, linalyl acetate, lemon oil, lavender oil, orange oil, and rose oil. The terpene gels show good release of the volatile components over a long period.
Quartz Crystal Microbalance Analyses of SpnR Binding Constants as a Negative Regulator of N-Acylhomoserine Lactone-dependent Quorum Sensing in Serratia marcescens AS-1
Authors: Takayama Yuriko , Nasuno Eri , Iimura Ken-ichi , Morohoshi Tomohiro , Kato Norihiro 
Published: July 2015

Abstract
Quartz crystal microbalance measurements suggest that a quorum-sensing LuxR homolog receptor SpnR in Serratia marcescens AS-1 dissociates from spn box after complexation with N-hexanoylhomoserine lactone (C6HSL). After reaching quorum of cells on increasing the C6HSL concentration, forming stable SpnR–C6HSL complex probably leads to conformational changes in the DNA-binding domain, and its binding constant reduces by one order after complexation. The interaction analyses of immobilized spn box on a gold electrode with additive SpnR clearly shows the negative regulation for spn operon.
Steady-state Fluorescence Investigation of Interaction between Pyrene-labeled Polysulfonates Carrying Hydrophobic Group and Surfactants
Authors: Mizusaki Masanobu 
Published: July 2015

Abstract
The interaction of hydrophobically random-modified and end-capped poly[2-(acrylamido)-2-methylpropanesulfonate]s, which are polyanions, with positively and negatively charged surfactants was investigated by steady-state fluorescence spectroscopy of labeled pyrene. The results revealed that both the polyanions interact with the positively charged surfactants more easily compared with the negatively charged surfactants although the polyanions do interact with the negatively charged surfactants due to hydrophobic interaction. Moreover, the end-capped polyanion had stronger electrostatic attraction with the positively charged surfactant compared with the random-modified polyanion.
Diseño de Elecciones colectivas y Agregación de Preferencias: Del Miedo y la Retórica a la Teoría de Juegos y el Neuromarketing
Authors: Murillo Marco Fidel Zambrano 
Published: July 2015

<p>El presente trabajo busca describir el desarrollo histórico del conjunto de tecnologías y dispositivos discursivos, racionales, cognitivos y de ingeniería política encaminados a modelar e influir en los procesos mediante los cuales las comunidades y sociedades realizan sus elecciones colectivas, legitimando en este proceso sus niveles de cohesión social y paradójicamente los mecanismos con los cuales se reafirma la dominación política. Se resalta básicamente dos alternativas en las elecciones colectivas frente a la cual se encuentran las sociedades contemporáneas: Una alternativa basada en la información plena (verdad) y la construcción moral de consensos. Otra alternativa basada en el miedo, la distorsión de información (falsedad), el engaño y la manipulación de las estructuras de decisión. </p>
Un recorrido por los Derechos colectivos en la jurisprudencia argentina
Authors: Posada Nohora Elena Pardo 
Published: July 2015

<p>La jurisprudencia argentina así como su legislación reconoce la tutela judicial de los derechos de incidencia colectiva por mandato de la reforma constitucional del año de 1994 art 43 y siguientes, normas que son interpretadas por la Corte Suprema de la Nación en sus pronunciamientos judiciales, a partir de ellos se ha establecido el alcance de los artículos constitucionales mencionados, como la legitimación en materia colectiva. Se presenta el tema investigado dividido en cuatro etapas que comienzan con el fallo Toninas en el año de 1983 hasta la demanda interpuesta por la unión de usuarios y consumidores contra telefónica comunicaciones personales S.A, donde se verifican los efectos comunes para los sujetos afectados, propios de la protección colectiva.</p>
El rol del profesorado en el manejo de la violencia escolar
Authors: Lesmes Sandra Luz Castro , Cardona Mariela Inés Sánchez , Rodríguez Javier Hernán Sánchez 
Published: July 2015

<p class="Style7">El artículo recoge una de las dimensiones que se construyeron en la investigación “Bullying: Construcción de lo Social en instituciones educativas, respuestas pedagógicas” de la Fundación Universitaria Luis Amigó Centro Regional Bogotá.</p><p class="Style7"> </p><p class="Style7">En este artículo se aborda la influencia del profesorado, en el marco de las relaciones de convivencia en los escenarios escolares. Analizando los problemas de convivencia al interior de los colegios, se tiende a pensar que los orígenes de los fenómenos de violencia escolar como es el caso del bullying, se explican o por la existencia de relaciones familiares inadecuadas, o por los problemas sociopolíticos del país. Frente a lo anterior, es evidente que faltan estudios que se ocupen de analizar en qué medida el tipo de interacción del profesorado con sus estudiantes, la manera como se comunica y ejerce la facultad de poder en los escenarios escolares, puede generar agresión a nivel físico, verbal como psicológico. En cuanto al tema, Romero Hernández (2009, p. 59), plantea que la facultad de poder puede utilizarse de forma positiva o negativa al interior de la comunidad educativa. En las ocasiones que se ejerce dicha potestad inadecuadamente ha sido observable que puede generar conductas de egocentrismo, imposición, explotación, adoctrinamiento, opresión, tiranía, humillación, entre otras, lo que incide negativamente en la calidad de los procesos formativos, de la convivencia escolar y de la gestión de los proyectos educativos institucionales.</p><p class="Style7"> </p><p class="Style7">El objetivo de este artículo es reflexionar la necesidad de no subvalorar ni restar importancia al tipo de relación propuesta por el profesorado con los estudiantes, como posible factor generador violencia escolar que puede obstaculizar el desarrollo de una cultura de paz en las instituciones educativas.</p><p class="Style7"> </p><p class="Style7">El artículo contiene tres apartados, en el primero, se plantea a groso modo los aspectos metodológicos, en el segundo se analiza como el quehacer del profesorado, puede contribuir a la de violencia en las aulas. En el tercero y último apartado se plantea, como la educación para la paz, fortalece una verdadera cultura de paz en las aulas de clase, la cual contribuye a la prevención del fenómeno del acoso escolar en las instituciones educativas. </p>
Derechos humanos: herramienta para resolver conflictos escolares en la discriminación de género
Authors: Bejarano Saira Alejandra Caicedo 
Published: July 2015

<p>Este artículo se encuentra encaminado a recopilar y analizar cómo los marcos de los organismos que diseñan y ejecutan la política educativa sobre Derechos Humanos establecidos en los currículos escolares, desarrollan competencias en los estudiantes para resolver conflictos escolares en la discriminación de género. Contexto del cual se parte para evidenciar las políticas de igualdad de género que se presentan en Colombia dentro de las instituciones educativas con el fin de realizar un diagnóstico de las falencias de las mismas.</p>
Política, poder e Internet: Nuevas posibilidades frente a viejos dilemas
Authors: Sierra Jerónimo Ríos 
Published: July 2015

<p>Internet y las nuevas tecnologías han reconfigurado la relación entre el Estado y la sociedad civil en torno al binomio conformado por el poder y la política. Bajo esta tesitura convergen nuevas posibilidades y viejos dilemas que deben adaptarse a dinámicas cambiantes, actuales, como la <em>transterritorialidad</em> de los movimientos sociales, la (auto) comunicación de masas o la redefinición del sentido de modernidad.</p><p> </p><p>Así, la sociedad civil desarrolla, gracias a Internet, un entramado organizativo, comunicativo y de participación que sirve de caldo de cultivo óptimo para la representación de nuevas disputas frente a un Estado-nación que sigue siendo, pese a todo, el referente en cuanto al análisis del poder formalmente institucionalizado.</p>
Association between balance of masticatory muscle activity during usual daily life and transverse craniofacial morphology or tooth contact area in patients with transverse jaw deformity: An electromyographic evaluation
Authors: Saifuddin Mohammed , Begum Shahana , Ueda Hiroshi M , Miyamoto Keisuke , Tanne Kazuo 
Published: July 2015

Introduction: It is considered now-a-days that patients with transverse craniofacial deformity might have differences in masticatory muscle activity between both sides; and as masticatory muscle activity takes place throughout the usual daily life; therefore, it might have some relation with the transverse craniofacial morphology. The present study was carried out to find out any association between balance of masticatory muscle activity during usual daily life and transverse craniofacial morphology or tooth contact area in patients with transverse jaw deformity.Subjects and Methods: All the controls and patients for the study were selected from our staffs and patients coming to Orthodontic Clinic, Hiroshima University Dental Hospital, respectively. Thirteen males and two females (mean and s.d. of ages: 28.6 ± 1.9 years) served as the controls. They had Angles Class I molar relationship, no severe malocclusion, no complaints of temporomandibular disorder (TMD).The patient group was consisted of 10 males and five females (mean and s.d. of ages: 19.9 ± 5.3 years) with lateral shift of the mandible. They had malocclusion such as cross-bite and severe crowding, but no complaints of TMD. Portable digital EMG recording device were used to record the EMG from the bilateral masster and anterior temporal muscles. The diurnal recording was carried out for consecutive 142 minutes and divided into two periods of usual daytime and mealtime for analysis. After the diurnal recording, the subjects were allowed to go back home with the electrodes in position and then nocturnal EMG recording was performed again at night with the usual sleeping posture for 142 minutes. Posteroanterior cephalometric analysis and tooth contact area were measured for all the subjects.Result: No significant correlations were found for both the muscles neither with transverse craniofacial morphology nor with the tooth contact area for all the three periods of usual daily life, although a significant correlation was detected between the A-B distance and AI of the anterior temporal muscle during usual daytime.Conclusion: It is suggested that masticatory muscle activity during usual daily life in patients with transverse craniofacial deformity may not be related only to such factors as skeletal deformity or tooth contact area but governed by other important factors like occlusal interference, premature contacts, instability and so on.Ban J Orthod & Dentofac Orthop, October 2012; Vol-3, No.1
Prevalence of Dental Health Problems among the Patients Attending in the Orthodontic Department of Dhaka Dental College & Hospital
Authors: Habib Md Ahsan , Rabbani Rashed Md Golam , Hossain Md Zakir 
Published: July 2015

Objectives: To know the prevalence & pattern of dental health problems among Bangladeshi people.Study design: Descriptive cross sectional study.Place of study: Department of Orthodontics & Dentofacial Orthopaedics of Dhaka Dental College & Hospital, Dhaka.Period of study: From September2011 to February2012.Sample selection: In this study, A total number of 500 patients (250 males & 250 females) were selected from Orthodontic Department of Dhaka Dental College & Hospital.Results: This was a cross sectional study conducted among 500 patients in the Department of Orthodontics and Dentofacial Orthopaedics, Dhaka Dental College and Hospital. Gingivitis is the commonest problem in Bangladeshi people according to present study. The second most dental problem is dental caries. The prevalence of orthodontic problems was comparable to the observations made by others. Males and females are equally affected with slight variations in the nature of problems among both genders.Conclusion: Good oral health is essential to improve individual overall health & well-being. We urge to take this information & use it for program planning & advocating for the health of patients, specially for the patients who will receive orthodontic treatment. Therefore, current orthodontic students should receive more education & training before the management of malocclusion to improve the overall quality of care for orthodontic patients.Ban J Orthod & Dentofac Orthop, October 2012; Vol-3, No.1
Influence of the size of incisors on the occurrence of crowding
Authors: Islam Md Sayeedul , Hossain Md Zakir 
Published: July 2015

Aim: The aim of the study was to determine the influence of the size of permanent incisors on the appearance of the crowding of the anterior segment of dental arches.Materials and Methods: The study included 100 subjects, aged 13-25 years. All the examinees were divided into two groups. The first group comprised 50 subjects (25 males and 25 females) who had marked symptoms of crowding, especially in the anterior segment. The second group comprised 50 subjects (25 males and 25 females) with normal occlusion. The measurement was performed using a digital caliper, 0.01 mm of accuracy. The following parameters were examined: mesiodistal (MD) and labiolingual (LL) diameter of the maxillary and mandibular incisors. The index of the crown of the tooth was calculated using the formula (MD/LL)×100.Results: The results of this study show that the mesiodistal diameter and the index of the crown of upper and lower incisors has a significantly higher value in both male and female in crowding compared with normal occlusion. In this study, the higher values of the index of tooth crown in patients with crowding, may be due to greater mesiodistal diameter of teeth.Conclusion: The results of this study suggest that increased tooth size has a contributory role in dental crowding.Ban J Orthod & Dentofac Orthop, October 2012; Vol-3, No.1