bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fortalecimiento de la Cátedra de la Paz en la Educación, a partir de la Ética, Cuidado y Toma de Decisiones, para los Estudiantes de Grado Once del Colegio Administración Robert Owen
Authors: Bernal Figueroa Yuly Milena , Zabaleta Ardila Andrea Johanna Zabaleta Ardila 
Published: July 2024

En la presente investigación se realizó el diseño de una estrategia pedagógica para el fortalecimiento de la Cátedra de la Paz en la educación, en el colegio Robert Owen de Bogotá, con un enfoque en la ética, el cuidado y la toma de decisiones aplicado a los estudiantes de grado once del Colegio, parte del reconocimiento de la importancia de la Cátedra de Paz, la formación cívica y los proyectos de vida de los estudiantes, para contribuir en la mejora de las condiciones sociales, culturales, políticas, económicas y ambientales desde la educación. Con un enfoque cualitativo de investigación, que favoreció el acercamiento al problema y la identificación de los elementos claves del PEI a la luz de las categorías, y mediante 3 momentos, el primer momento de descripción, el segundo momento de análisis y el tercer momento propositivo. Como resultado, se evidencia la necesidad de implementar estrategias formativas que fortalezcan los proyectos de vida de los estudiantes, basándolos en la ética y moralidad, el cuidado de si mismo, del otro y del entorno y la toma de decisiones consientes, que le permitan asumir con responsabilidad su rol como ciudadano activo.
How brands are using nonlinear marketing to address consumer resistance to traditional marketing strategies
Authors: Turner Jamie , Shah Reshma , Jain Varsha 
Published: July 2024

Consumer behaviour and media consumption habits are changing at a rapid pace. Reactions to stimuli that were once easy to predict are no longer predictable, and typical responses to marketing actions have become completely atypical. As a result, traditional approaches to marketing are losing their effectiveness. This paper sheds light on a new approach many brands are adopting, which we call nonlinear marketing. Nonlinear marketing is a way for brands to weave themselves into the fabric of a consumer’s life. Rather than relying on the traditional approach whereby brands might interrupt a consumer’s life with 30-second television commercials or the like, brands become a seamless part of their consumers’ daily journey via nonlinear marketing. The result is a richer, more robust experience for the consumer and a more effective, longer-lasting relationship for the marketer.
Pengaruh Gaya Hidup Dan Harga Terhadap Keputusan Pembelian Handphone Iphone
Authors: Miftahudin Miftahudin , Haryanti Intisari , Ernawati Sri 
Published: July 2024

Keputusan pembelian konsumen tidak terlepas dari gaya hidup mereka yang ingin membeli produk yang bermanfaat dan mempunyai kualitas yang baik. gaya hidup yang diukur berdasarkan aktivitas dimana seseorang melakukan kegiatan dalam memenuhi kebutuhannya seperti pekerjaan, hobi, belanja, hiburan, olahraga, dan minat seseorang berdasarkan keinginan terhadap produk yang diinginkan, serta pendapat atau pandangan seseorang terhadap produk yang akan dibeli sehingga dapat mempengaruhi perilaku keputusan konsumen khususnya pada Mahasiswa STIE Bima. Fenomena dalam penelitian ini adalah Sebagian besar mahasiswa STIE Bima menggunakan handphone Iphone. Tujuan Penelitian ini untuk mengetahui Pengaruh Gaya hidup dan Harga Terhadap Keputusan Pembelian Handphone iphone (Studi Pada Mahasiswa STIE Bima). Teknik pengambilan sampel menggunakan kuesioner dengan sumber peneliti yaitu Mahasiswa STIE Bima, penelitian ini menggunakan jenis penelitian asosiatif. instrumen penelitian menggunakan angket dengan skala likert dengan populasi unknown population, yaitu mahasiswa yang menggunakan handphonr iphone dengan jumlah sampel 50 orang. Teknik pengumpulan datanya dengan membagikan kuesioner kepada mahasiswa penggguna handphonr iphone. Hasil penelitian ini menunjukkan bahwa bahwa Gaya Hidup tidak pengaruh secara signifikan terhadap Keputusan Pembelian Handphone Iphone (Studi pada mahasiswa STIE Bima), Harga berpengaruh secara signifikan terhadap Keputusan Pembelian Handphone Iphone (Studi pada mahasiswa STIE Bima) dan Gaya Hidup,dan harga, berpengaruh signifikan terhadap Keputusan Pembembelian. Dibuktikan dengan besarnya pengaruhnya sebesar 31,2%.
PERANCANGAN SISTEM INFORMASI PENGOLAHAN DATA MAHASISWA MAGANG DI PERUSAHAAN BERBASIS WEB
Authors: Marpaung Puja Hati , Dahri Nuraeni , Yahyan Wahyuni 
Published: July 2024

Sistem ini dirancang untuk Pengelolahan data Mahasiswa magang di CV. Multi Maju sebagai upaya mengatasi masalah pengolahan data yang belum efektif dan efisien, proses pendataan yang di lakukan secara manual cukup memakan waktu brdampak terhadap teknis pada laporan pengawasan dan monitoring mahasiswa.
Perancangan sistem ini dibangun menggunakan platform website yang di jalankan secara online. Metode pengembangan sistem menggunakan System Development Life Cycle (SDLC) Waterfall yang terdiri atas 5 tahapan, yakni, Analisys, Design, Implementation, Testing Maintance,. Bahasa pemrograman yang digunakan adalah PHP dengan database MariaDb. Alat bantu perancangan sistem menggunakan metode Unified Modeling Langguange (UML) yakni UseCase Diagram, Activity Diagram, Sequance Diagram, dan Class Diagram.
perancangan sistem informasi pengelolahan data mahasiswa magang di CV. Multi Maju memudahkan bagian administrasi dalam mengelola data mahasiswa secara cepat dan akurat. Perancangan aplikasi berbasis Web pada CV. Multi Maju ini diharapkan dapat membantu bagian admin dalam mengelola data dan mahasiswa untuk melihat nilai.
SISTEM INFORMASI PENJUALAN EMAS BERBASIS WEB PADA TOKO ANUGERAH BINTANG BARU PAYAKUMBUH
Authors: Febiolla Detria , Sutardjo Agus , Dahri Nuraeni 
Published: July 2024

Perancangan sistem ini bertujuan merancang sistem informasi penjualan emas sebagai upaya mengatasi permasalahan sistem informasi penjualan yang belum efektif dan efisien. Proses pelaksanaan penjualan dan pengolahan data penjualan yang manual mempengaruhi hasil.
Perancangan sistem ini dibangun menggunakan platform website dan dijalankan secara online. Metode penelitian menggunakan System Development Life Cycle (SDLC) dengan pendekatan model Waterfall yang terdiri atas 5 tahapan, yakni, a) Analisys b) Design c) Implementation d) Maintance e) Planing. Bahasa pemrograman yang digunakan adalah (PHP), dan aplikasi database menggunakan pengolah data (MySql) sebagai database (RDBMS). Alat bantu perancangan sistem menggunakan metode UML (unifed Modeling Language) dengan menggunakan 4 (empat) diagram sesuai kebutuhan perancangan, yakni Use Case Diagram, Activity Diagram, Class Diagram, dan SequenceDiagram.
Rancangan Sistem Informasi Penjualan Emas Berbasis Web yang dapat mempermudah proses penjualan emas, dan memudahkan melihat stock emas secara akurat yang tersedia di toko. Sistem ini juga memudahkan penghitungan omset dan keuntungan pada toko.
Sistem Informasi Penjualan Emas Berbsis Web Pada Toko Anugerah Bintang Baru ini secara khusus dapat memudahkan dalam meningkatkan proses transaksi penjualan. Perancangan sistem ini dapat mengatasi hambatan proses transaksi penjualan menjadi lebih akurat.
Pengaruh Inflasi, Return on Asset , dan Return on Equity Terhadap Keputusan Investasi Saham Pada Perusahaan Manufaktur Yang Terdaftar di BEI
Authors: Atu Rohmah Sifa , Michellita Michellita , Permatasari Taris Wulan , Safrudin Ilham 
Published: July 2024

Penelitian ini bertujuan untuk menganalisis pengaruh inflasi, Return on Assets (ROA), dan Return on Equity (ROE) terhadap keputusan investasi saham pada perusahaan manufaktur yang terdaftar di Bursa Efek Indonesia (BEI) antara tahun 2017 dan 2022. Metode penelitian menggunakan teknik purposive sampling untuk memilih 50 perusahaan manufaktur dari populasi 144 perusahaan yang memenuhi kriteria tertentu. Data dikumpulkan dari laporan tahunan perusahaan dan dianalisis menggunakan regresi linier berganda. Hasil analisis menunjukkan bahwa inflasi dan ROE memiliki pengaruh signifikan terhadap keputusan investasi, sementara ROA tidak memiliki pengaruh signifikan. Inflasi yang tinggi cenderung menurunkan minat investasi, sedangkan ROE yang tinggi meningkatkan minat investasi. Temuan ini memberikan wawasan bagi investor dalam mempertimbangkan faktor-faktor ekonomi makro dan kinerja perusahaan sebelum membuat keputusan investasi.

This study aims to analyze the impact of inflation, Return on Assets (ROA), and Return on Equity (ROE) on investment decisions in stocks of manufacturing companies listed on the Indonesia Stock Exchange (IDX) between 2017 and 2022. The research method employs purposive sampling to select 50 manufacturing companies from a population of 144 companies that meet specific criteria. Data were collected from the companies' annual reports and analyzed using multiple linear regression. The analysis results indicate that inflation and ROE have a significant impact on investment decisions, while ROA does not have a significant influence. High inflation tends to reduce investment interest, whereas high ROE increases investment interest. These findings provide insights for investors to consider macroeconomic factors and company performance before making investment decisions.
Characterization for Qualitative Traits in Segregating Population of Faba Bean (Vicia faba L.)
Authors: Jha A.K. , Ranjan A. , Choudhary A.K. , Bhardwaj A. , Verma R.B. , Kumar Abhishek 
Published: July 2024

The present investigation revealed the wide variation for qualitative characters viz, stem colour, leaf colour, flower colour and pod colour among the eight F3 populations of faba bean. Wide range of variability was observed for morphological characters like flower colour (white) under the crosses Bak-1 × Bak-11 and Bak-12 × Bak-5 (96.25%), Bak-1 × Bak-20 (92.50%), Bak-1 × Bak-5 (91.25%), Bak-2 × Bak-5, Bak-2 × Bak-20 and Bak-16 × Bak-20 (90%). Pod colour (light green) was observed in crosses Bak-1 × Bak-20 and Bak-2 × Bak-11 (97.50%) whereas pod colour (green) in Bak-16 × Bak-20 (86.25%). Leaf colour (light green) in the crosses Bak-2 × Bak-20 (92.50%) followed by Bak-2 × Bak-5, Bak-2 × Bak-11 (87.50 %) and stem colour (light green) was observed maximum in Bak-1 × Bak-20 and Bak-2 × Bak-11 (95 %) followed by Bak-2 × Bak-20 (93.75%) whereas only seven crosses had diverse flower colour viz. violet (1.25%) in Bak-1 × Bak-5 and Bak-2 × Bak-20, dark brown (2.50%) in Bak-1 × Bak-11, Bak-2 × Bak-20, Bak-12 × Bak-5 and Bak-16 × Bak-20 and in cross Bak-1 × Bak-5 (1.25%), light brown (2.50%) in Bak-1 × Bak-5, Bak-2 × Bak-5 and Bak-12 × Bak-5 and (1.25%) was observed in Bak-1 × Bak-11 and Bak-2 × Bak-1, pink (1.25%) in Bak-2 × Bak-11 and Bak-16 × Bak-20 and mixed (white petals with black, brown and purple wing melanin spot) (1.25%) in crosses Bak-2 × Bak-5 and Bak-2 × Bak-11. It was observed that only three crosses had diverse pod colour viz. green in cross combination Bak-1 × Bak-20 (2.50%) and Bak-2 × Bak-11 (1.25%) and dark green in cross combinations Bak-12 × Bak-5 (2.50%) and Bak-2 × Bak-11 (1.25%). However, previous work on the characterization of faba bean for qualitative traits has been limited. Thus, the present study suggested that these traits maybe useful for further plant breeding programmes.
Heater‐induced ionization inferred from spectrometric airglow measurements
Authors: Hysell D. L. , Miceli R. J. , Kendall E. A. , Schlatter N. M. , Varney R. H. , Watkins B. J. , Pedersen T. R. , Bernhardt P. A. , Huba J. D. 
Published: February 2014

AbstractSpectrographic airglow measurements were made during an ionospheric modification experiment at High Frequency Active Auroral Research Program on 12 March 2013. Artificial airglow enhancements at 427.8, 557.7, 630.0, 777.4, and 844.6 nm were observed. On the basis of these emissions and using a methodology based on the method of Backus and Gilbert (1968, 1970), we estimate the suprathermal electron population and the subsequent equilibrium electron density profile, including contributions from electron impact ionization. We find that the airglow is consistent with heater‐induced ionization in view of the spatial intermittency of the airglow.
Unusually large shear wave anisotropy for chlorite in subduction zone settings
Authors: Mookherjee Mainak , Mainprice David 
Published: February 2014

AbstractUsing first principle simulations we calculated the elasticity of chlorite. At a density ρ~ 2.60 g cm−3, the elastic constant tensor reveals significant elastic anisotropy: VP ~27%, VS1 ~56%, and VS2 ~43%. The shear anisotropy is exceptionally large for chlorite and enhances upon compression. Upon compression, the shear elastic constant component C44 and C55 decreases, whereas C66 shear component stiffens. The softening in C44 and C55 is reflected in shear modulus, G, and the shear wave velocity, VS. Our results on elastic anisotropy at conditions relevant to the mantle wedge indicates that a 10–20 km layer of hydrated peridotite with serpentine and chlorite could account for the observed shear polarization anisotropy and associated large delay times of 1–2 s observed in some subduction zone settings. In addition, chlorite could also explain the low VP/VS ratios that have been observed in recent high‐resolution seismological studies.
A tool for selective inline quantification of co‐eluting proteins in chromatography using spectral analysis and partial least squares regression
Authors: Brestrich Nina , Briskot Till , Osberghaus Anna , Hubbuch Jürgen 
Published: February 2014

ABSTRACTSelective quantification of co‐eluting proteins in chromatography is usually performed by offline analytics. This is time‐consuming and can lead to late detection of irregularities in chromatography processes. To overcome this analytical bottleneck, a methodology for selective protein quantification in multicomponent mixtures by means of spectral data and partial least squares regression was presented in two previous studies. In this paper, a powerful integration of software and chromatography hardware will be introduced that enables the applicability of this methodology for a selective inline quantification of co‐eluting proteins in chromatography. A specific setup consisting of a conventional liquid chromatography system, a diode array detector, and a software interface to Matlab® was developed. The established tool for selective inline quantification was successfully applied for a peak deconvolution of a co‐eluting ternary protein mixture consisting of lysozyme, ribonuclease A, and cytochrome c on SP Sepharose FF. Compared to common offline analytics based on collected fractions, no loss of information regarding the retention volumes and peak flanks was observed. A comparison between the mass balances of both analytical methods showed, that the inline quantification tool can be applied for a rapid determination of pool yields. Finally, the achieved inline peak deconvolution was successfully applied to make product purity‐based real‐time pooling decisions. This makes the established tool for selective inline quantification a valuable approach for inline monitoring and control of chromatographic purification steps and just in time reaction on process irregularities. Biotechnol. Bioeng. 2014;111: 1365–1373. © 2014 Wiley Periodicals, Inc.
Strong cellulase inhibition by Mannan polysaccharides in cellulose conversion to sugars
Authors: Kumar Rajeev , Wyman Charles E. 
Published: February 2014

ABSTRACTCellulase enzymes contribute a major fraction of the total cost for biological conversion of lignocellulosic biomass to fuels and chemicals. Although a several fold reduction in cellulase production costs and enhancement of cellulase activity and stability have been reported in recent years, sugar yields are still lower at low enzyme doses than desired commercially. We recently reported that hemicellulose xylan and its oligomers strongly inhibit cellulase and that supplementation of cellulase with xylanase and β‐xylosidase would significantly reduce such inhibition. In this study, mannan polysaccharides and their enzymatically prepared hydrolyzates were discovered to be strongly inhibitory to fungal cellulase in cellulose conversion (>50% drop in % relative conversion), even at a small concentration of 0.1 g/L, and inhibition was much greater than experienced by other known inhibitors such as cellobiose, xylooligomers, and furfural. Furthermore, cellulase inhibition dramatically increased with heteromannan loading and mannan substitution with galactose side units. In general, enzymatically prepared hydrolyzates were less inhibitory than their respective mannan polysaccharides except highly substituted ones. Supplementation of cellulase with commercial accessory enzymes such as xylanase, pectinase, and β‐glucosidase was effective in greatly relieving inhibition but only for less substituted heteromannans. However, cellulase supplementation with purified heteromannan specific enzymes relieved inhibition by these more substituted heteromannans as well, suggesting that commercial preparations need to have higher amounts of such activities to realize high sugar yields at the low enzyme protein loadings needed for low cost fuels production. Biotechnol. Bioeng. 2014;111: 1341–1353. © 2014 Wiley Periodicals, Inc.
Salting‐out thin‐layer chromatography and computational analysis of some oral hypoglycemic drugs
Authors: Mohamed Abdel Maaboud Ismail , Mohamed Fardous Abdel‐Fattah , Ahmed Sameh Abdel‐Raouf , Aboraia Ahmed Safwat , Mohamed Yahya Abduh Salim 
Published: February 2014

ABSTRACTA quantitative structure–retention relationship study of some oral hypoglycemic drugs was carried out using a salting‐out thin‐layer chromatographic technique. Aqueous solution of ammonium sulfate and acetonitrile was used as a mobile phase. It was established that the applied mobile phase has different effects on retention of the studied oral antidiabetic drugs. The factors that affect the salting‐out process were determined. In this study a good correlation between the structures of the investigated drugs with the retention data and molecular descriptors was established throughout computational analysis and using molecular operating environment software, focusing on octanol/water partition coefficient, molar refractivity, total hydrophobic surface area, hydrophobic volume, Van der Waals energy and solvation energy. Quantitative structure–retention relationship modeling for the separation of the investigated drugs was carried out, validated and evaluated. Copyright © 2014 John Wiley & Sons, Ltd.
Characterization of Secondary Metabolites, Biological Activity and Glandular Trichomes of Stachys tymphaeaHausskn. from the Monti Sibillini National Park (Central Apennines, Italy)
Authors: Venditti Alessandro , Bianco Armandodoriano , Nicoletti Marcello , Quassinti Luana , Bramucci Massimo , Lupidi Giulio , Vitali Luca Agostino , Papa Fabrizio , Vittori Sauro , Petrelli Dezemona , Maleci Bini Laura , Giuliani Claudia , Maggi Filippo 
Published: February 2014

AbstractStachys tymphaea (Lamiaceae) is a perennial herb growing in forest openings and dry meadows of central and southern Italy. It was investigated for the first time here, determining the content of secondary metabolites, the micromorphology of glandular trichomes, the histochemical localization of secretion, and the biological activity of the volatile oil, namely, the cytotoxic, antioxidant, and antimicrobial properties. The plant showed a peculiar molecular pattern, being rich of biophenolic compounds as flavonoids, phenylethanoid glycosides, and caffeoylquinic acid derivatives, but poor of iridoids, which are known as marker compounds of the genus Stachys. The essential oil was characterized by GC‐FID and GC/MS analyses, revealing a high percentage of sesquiterpene hydrocarbons (54.6%), with germacrene D (30.0%) and (E)‐β‐farnesene (12.4%) as the most abundant compounds, while other main components were representatives of the diterpenes (19.2%), represented mainly by (E)‐phytol (11.9%). This composition supported the taxonomic relationships in the genus Stachys, which comprises oil‐poor species producing essential oils rich in hydrocarbons, with germacrene D as one of the predominant components. The micromorphological study revealed three types of glandular hairs, i.e., Type A peltate trichomes, being the primary sites of essential oil biosynthesis, Type B short‐stalked trichomes, typical mucopolysaccharide producers, and Type C long capitate trichomes, secreting a complex mixture of both lipophilic and hydrophilic substances, with a major phenolic fraction. Moreover, the MTT assay revealed the potential of the volatile oil to inhibit A375, HCT116, and MDA‐MB 231 tumor cells lines (IC50 values of 23.9–34.4 μg/ml).
Chemical Variability of Xylopia quintasiiEngl. & Diels Leaf Oil from Côte d'Ivoire
Authors: Yapi Thierry Acafou , Boti Jean Brice , Tonzibo Zanahi Félix , Ahibo Coffy Antoine , Bighelli Ange , Casanova Joseph , Tomi Félix 
Published: February 2014

AbstractThe chemical composition of 42 essential‐oil samples isolated from the leaves of Xylopia quintasii harvested in three Ivoirian forests was investigated by GC‐FID, including the determination of retention indices (RIs), and by 13C‐NMR analyses. In total, 36 components accounting for 91.9–92.6% of the oil composition were identified. The content of the main components varied drastically from sample to sample: (E)‐β‐caryophyllene (0.9–56.9%), (Z)‐β‐ocimene (0.3–54.6%), β‐pinene (0.8–27.9%), α‐pinene (0.1–22.8%), and furanoguaia‐1,4‐diene (0.0–17.6%). The 42 oil compositions were submitted to hierarchical cluster and principal components analysis, which allowed the distinction of three groups within the oil samples. The composition of the oils of the major group (22 samples) was dominated by (E)‐β‐caryophyllene. The oils of the second group (12 samples) contained β‐pinene and α‐pinene as the principal compounds, while the oils of the third group (8 samples) were dominated by (Z)‐β‐ocimene, germacrene D, (E)‐β‐ocimene, and furanoguaia‐1,4‐diene. The oil samples of Group I and II came from clay‐soil forests, while the oil samples belonging to Group III were isolated from leaves harvested in a sandy‐soil forest.
Focal adhesion kinase (FAK) siRNA inhibits human hypertrophic scar by suppressing integrin α, TGF‐β and α‐SMA
Authors: Chen Rui , Zhang Zhiliang , Xue Zhujia , Wang Lin , Fu Mingang , Lu Yi , Bai Ling , Zhang Dongqing , Fan Zhihong 
Published: February 2014

AbstractThe effect of focal adhesion kinase (FAK) on suppressing scarring and the potential molecular mechanism underlying it has been investigated. Ten samples of human hypertrophic scars (HS) tissue cultured in vitro were transfected with FAK siRNA mediated by liposome. Quantitative real‐time PCR was used to detect the expression of integrin α, transforming growth factor‐β (TGF‐β), FAK and α‐smooth muscle actin (α‐SMA) after transfection. MTT assay was used as a measure of fibroblast proliferation. Flow cytometry and3H‐proincorporation technique gave measurements of the cell cycle and the quantity of collagen synthesis, respectively. Expression of FAK was effectively blocked, accompanied by decreasing expression of integrin α, TGF‐β and α‐SMA in hypertrophic scars fibroblast (HSFB) cells. One to 4 h after transfection with FAK siRNA, proliferation of HSFB cells was strongly inhibited (P < 0.01), reaching a maximum at 48 h. The proportion of G1cells was higher and the proportion of the S and G2cells lower after transfection. The amount of collagen synthesis in HSFB cells decreased when HSFB cells were transfected for 48 h. RNA interference targeting the FAK gene can block the two abnormal signal transduction pathways mediated by the integrin and TGF‐β receptors that are responsible for hyperplasia and contracture of the scar, making FAK iRNA therapy a potentially effective approach in HS treatment.