bluuebunny/crossref_metadata_2025_split huggingface dataset:
Spatial Analyses in the Research of Land Cover Changes (A Case Study)
Authors: Mazurek Kinga 
Published: October 2015

Abstract
Increasing human activity significantly influences the geographic environment. The effects of excessive anthropogenic pressure are manifested by changes in land cover and in landscape structure, and land cover changes can particularly well observed in river valleys. In this study we aimed to determine the transformations of land use in 13.9 sq km of the Silesian Voivodeship in southern Poland, including parts of the city of Ruda Slaska and Mikolow County by analyzing changes in land cover that occurred from 1827-2012 and archival and contemporary topographic maps, and aerial photos were used as primary source materials. All materials were prepared with the use of Geographic Information Systems (GIS), using spatial analyses, such as kernel density and point density in order to define land cover structure changes.
Results show the development of residential areas and the fragmentation of large structures that have occurred over the time period.
Strategies For Immobilization Of Bioactive Organic Molecules On Titanium Implant Surfaces – A Review
Authors: Panayotov Ivan V. , Vladimirov Boyan S. , Dutilleul Pierre-Yves C. , Levallois Bernard , Cuisinier Frédéric 
Published: October 2015

Abstract
Numerous approaches have been used to improve the tissue-implant interface of titanium (Ti) and titanium alloy (Ti6Al4V). They all aim at increasing cell migration and attachment to the metal, preventing unspecific protein adsorption and improving post-implantation healing process. Promising methods for titanium and titanium alloy surface modification are based on the immobilization of biologically active organic molecules. New and interesting biochemical approaches to such surface modification include layer-by-layer deposition of polyelectrolyte films, phage display-selected surface binding peptides and self-assembled DNA monolayer systems. The present review summarizes the scientific information about these methods, which are at in vitro or in vivo development stages, and hopes to promote their future application in dental implantology and in oral and maxillofacial surgery.
Reconstruction Of Glenoid Bone Deficiency With Porous Titanium Nickelide In Recurrent Anterior Shoulder Instability
Authors: Prokhorenko Valery M. , Fomenko Sergey M. , Filipenko Pavel V. , Turkov Petr S. 
Published: October 2015

AbstractIntroduction:One of the main causes of recurrent shoulder instability is a bone defect of the front edge of the glenoid. The available techniques for reconstruction of this bone defect, however, have some disadvantages.Objective:The aim of this study was to develop a new method that can reduce the number of postoperative complications and improve the efficiency of surgical treatment of recurrent anterior shoulder instability with glenoid bone defect.Materials and methods:We present here a new method for surgical treatment of post-traumatic recurrent anterior shoulder instability with bony defects using porous NiTi. We operated 5 patients using this method. Computed tomography was used in the preoperative preparation of the NiTi graft. The graft was sawed from a cylindrical billet about 1 cm in thickness. Two screw holes were then made with a drill. The prepared graft was subsequently installed in the area of the glenoid bone defect.Results:There were no recurrences of the dislocation after the surgical treatment. All patients returned to their previous levels of physical activity.Conclusions:The proposed method is an alternative to Latarjet procedure and iliac crest bone grafting. The advantages of this method are accurate reconstruction of the bone defect, minimal risk of recurrences, no resorption, and reduction of procedure time.
Cutaneous Leishmaniasis – Dermoscopic Findings And Cryotherapy
Authors: Dobrev Hristo P. , Nocheva Desislava G. , Vuchev Dimitar Iv. , Grancharova Rumyana D. 
Published: October 2015

AbstractWe present a 60-year-old male patient who, three months after a holiday in Southern Greece, found a small ‘pimple’ on his back, which gradually got as big as a small walnut, the central part becoming ulcerated and scabby. Dermatological examination found an erythematous-to-livid nodular lesion on the right shoulder; it was 16 mm in diameter with central ulceration, covered with brownish crust which discharged pus-like secretion upon pressure. Microscope examination of Romanowsky-Giemsa stained lesion material detected amastigote forms ofLeishmania tropica. The culture investigation and serological tests for leishmaniasis were negative. Dermoscopy of the lesion found the following features: erythema, hyperkeratosis, central ulceration covered with brownish crust, “yellow tears-like” structures and “white starburst-like” patterns, and various vascular structures (including dotted vessels, comma-shaped vessels, hairpin- and glomerular-like vessels). The patient was diagnosed with cutaneous leishmaniasis and underwent four cryotherapy sessions every other week with excellent therapeutic results - complete resolution of infiltrate with subsequent gentle hypopigmented scarring. In conclusion, dermoscopy is an easily accessible non-invasive method which can be useful for the diagnosis of cutaneous leishmaniasis. Cryotherapy is the treatment of choice for single skin lesions.
Thoracic Meningioma In Combination With Severe Lumbar Spinal Stenosis Presenting With Atypical Neurological Deficit
Authors: Kehayov Ivo I. , Raykov Stephan D. , Hubavenska Iveta N. , Davarski Atanas N. , Kitova Tanya T. , Zhelyazkov Christo B. , Kitov Borislav D. 
Published: October 2015

Abstract
We report on a case of a 47-year-old female patient with a long history of low back pain irradiating bilaterally to the legs. Twenty days before admission to our clinic, she had developed progressive weakness in the legs, more pronounced on the left side. The initial neurological examination revealed signs of damage to both the cauda equina and the spinal cord. The neuroimaging studies (computed tomography, myelography and magnetic-resonance tomography) found spinal stenosis most severe at L4-L5 level, and right lateral thoracic intradural-extramedullary tumor at T9-T10 level.
The patient underwent two neurosurgical procedures. The first stage included microsurgical resection of the thoracic lesion and the second stage aimed at decompressing the lumbar spinal stenosis.
To avoid missing a diagnosis of thoracic lesions, it is necessary to perform a thorough neurological examination of the spinal cord motor and sensory functions. In addition, further MRI examination of upper spinal segment is needed if the neuroimaging studies of the lumbar spine fail to provide reasonable explanation for the existing neurological symptoms.
Characterizing evidentiality
Authors: Brugman Claudia M. , Macaulay Monica 
Published: October 2015

AbstractThis article examines theoretical and typological characterizations of evidentials. Based on the literature and newly analyzed data from Karuk (a Native American language of California), we argue that two properties are criterial: (i) marking source of evidence and (ii) membership in grammatical systems. Other properties vary crosslinguistically: presence of epistemic, illocutionary, or mirative meaning; speaker deixis; obligatoriness; complementarity of meaning with other items; and truth-conditionality. The values of these variable properties cannot be assumed but must be empirically determined for individual items and languages. Our characterization can serve as a guide for research, examination of the relationship between evidentiality and other categories, and typological work on evidentials.
Continued Smoking in Lung Transplant Patients: A Cross Sectional Survey
Authors: Zmeškal Miroslav , Králíková Eva , Kurcová Ivana , Pafko Pavel , Lischke Robert , Fila Libor , Bartáková Lucie Valentová , Fraser Keely 
Published: October 2015

Abstract

Introduction
Smoking is associated with a higher incidence of post-lung transplantation complications and mortality. Prior to inclusion on the lung transplant waiting list in the Czech Republic, patients are supposed to be tobacco free for at least 6 months. Our aim was to determine the prevalence of smoking, validated by urinary cotinine, among patients post lung transplantation and prior to inclusion on the transplant waiting list.

Methods
Between 2009 and 2012, we conducted a cross-sectional survey of urinary cotinine to assess tobacco exposure in 203 patients in the Lung Transplant Program in the Czech Republic. We measured urinary cotinine in 163 patients prior to inclusion on the transplantation waiting list, and 53 patients post bilateral lung transplantation.

Results
5.1% (95% CI 0.078 to 0.269) of all lung transplant recipients had urinary cotinine levels corresponding to active smoking; and a further 3.8% (95% CI 0.007 to 0.116) had borderline results. Compared to patients with other diagnoses, patients with COPD were 35 times more likely to resume smoking post-transplantation (95% CI 1.92 to 637.37, p-value 0.016). All patients who tested positive for urinary cotinine levels were offered smoking cessation support. Only one Tx patient sought treatment for tobacco dependence, but was unsuccessful.

Conclusion
Smoking resumption may be an underrecognized risk for lung transplantation recipients, particularly among patients with chronic obstructive pulmonary disease. More rigorous screening, as well as support and treatment to stop smoking among these patients are needed.
α1B-Adrenoceptor signaling molecule expression in Alzheimer’s disease brain tissue / Alzeimer hastalığı olan beyin dokusunda α1B-Adrenoseptör Sinyal Molekülü Ekspresyonu
Authors: Kim Jin Hee , Lee Sang Cheol , Lim Jae Yong , Kim Dong Seok , Yun Hye Young , Kwon Nyoun Soo , Im Mie Jae , Baek Kwang Jin 
Published: October 2015

AbstractObjective: Gαh (tissue transglutaminase; TGII), known as the α1B-adrenoceptor signal mediator, is a bifunctional enzyme possessing transglutaminase and guanosine triphosphatase activities. The microtubule-associated protein tau plays a role in formation of neurofibrillary tangles in Alzheimer’s disease (AD) brain. Tau is also known as a substrate of transglutaminase. We aimed to better understand the correlation between α1B-adrenoceptor signaling and AD.Methods: We examined not only the cross-linking ability of TGII for tau, but also the expression level of tau as well as α1B-adrenoceptor signaling molecules, TGII and phospholipase C-δ1, in the human brain.Results: When the tau protein was assayed as a transglutaminase substrate of TGII, tau proteins formed cross-linked products. However, phospholipase C-δ1 inhibited transglutaminase activity in TGII to cross-link with tau in vitro. The amount of expressed mRNA in AD brain tissue was elevated 2~10 fold for tau and 3~20 fold for TGII. Consistent with these observations, the densities of expressed proteins in AD brain tissue also increased 9 fold for tau and 15 fold for TGII. Moreover, phospholipase C-δ1, which is a negative regulator for transglutaminase activity of TGII, also increased 2~25 fold for mRNA as well as 8 fold for protein in AD brain tissue. In contrast, expressed mRNA and protein activity for α1B-adrenoceptor were almost the same between AD and normal brains.Conclusion: These results suggest that the α1B-adrenoceptor signal mediator, TGII and tau, as a substrate of TGII might have a pathophysiological role in AD, but this correlation may be independent of the α1B-adrenoceptor signaling system, including α1B-adrenoceptor and phospholipase C-δ1.
Spectroscopic characterization of synthetic heteroatom-functionalized fluorescent probes for bioimaging / Sentetik heteroatom-fonksiyonelize floresans probların biyogörüntüleme uygulamaları için spektroskopik karakterizasyonu
Authors: Dilek Özlem 
Published: October 2015

Abstract
Objective: Fluorescent probes are essential tools for monitoring biological systems in cellular environment. Several boron dipyrromethene (BODIPY) derived fluorescent probe derivatives have been synthesized by nucleophilic substitution reaction and their spectroscopic properties have also been determined.
Methods: Initial BODIPY dye framework was prepared from the reaction of pyrrole-2-carbaldehyde and benzaldehyde and then readily reacted with heteroatom-based nucleophiles at 3- and 5- position of BODIPY core. The spectroscopic properties of these new molecules have been reported.
Results: Amine based nucleophiles tend to produce broad absorption bands on the spectra. Our studies indicated that heteroatom-based nucleophiles on the BODIPY core resulted in a red shift on the absorption and emission spectra.
Conclusion: The synthesized fluorophores can therefore be potentially used as imaging agents for biological labeling.
Reaction of the CF3 Radical with Various Cations (Ar+, Xe+, O2
+, NO+, CO2
+, C2F5
+)
Authors: Shuman Nicholas S. , Wiens Justin P. , Sawyer Jordan C. , Ard Shaun G. , Martinez Jr. Oscar , Miller Thomas M. , Viggiano Albert A. 
Published: October 2015

Abstract
The kinetics of reactions of the trifluoromethyl radical
(CF3) with several simple cations (Ar+,
Xe+, O2
+, NO+, CO2
+,
C2F5
+) are studied via the variable electron and
neutral density attachment mass spectrometry (VENDAMS)
technique. CF3 is produced via dissociative electron
attachment to CF3I, resulting in radical concentrations that
are smaller than produced using pyrolysis methods, but better
quantified. Rate constants and product branching fractions are
reported, with typical uncertainties of ∼ 30%. Three of
the reactions, Ar+, O2
+, and
C2F5
+ proceed near the calculated collisional rate
constant, while the other reactions are between 10% – 30%
efficient. The inefficiency of the reactions of Xe+ and
CO2
+ can be explained by the reactions strictly obeying
spin-conservation. The reaction of Ar+ yields predominantly
(90%) CF2
+ via dissociative charge transfer,
with a minor channel to CF3
+. The reaction of
C2F5
+ yields predominantly CF3
+ with
a second channel (∼ 25%) yielding
C2F4
+ and CF4, the only example here of
a bond-breaking and bond-making reaction. For the other four
reactions, only charge transfer to yield CF3
+ is
observed. Rate constants for these same ions with CF3I are
also reported and found to be rapid with a variety of products formed.
Accelerometer-Based Monitoring of Upper Limb Movement in Older Adults With Acute and Subacute Stroke
Authors: Narai Emi , Hagino Hiroshi , Komatsu Taiki , Togo Fumiharu 
Published: October 2015

Background and Purpose:
Use of the affected extremity during daily life is important if disuse atrophy is to be prevented after stroke. This study examined whether objectively measured real-world upper limb movement is associated with the amount of use of the affected upper limb, as assessed by a standardized assessment tool in older adults with acute or subacute stroke. This study also examined whether the real-world upper limb movement is associated with the extent of impairment of upper and lower extremities.

Methods:
The participants were 19 older adults with hemiparesis from acute or subacute stroke [17 (7) days after the stroke]. All the participants wore 3 accelerometers—1 on each wrist (bilateral accelerometry) and 1 on the waist—throughout a 24-hour period. They were interviewed about use of their upper limb in the real-world setting using a Motor Activity Log. Functions of the affected upper limb or upper and lower limbs were assessed using the National Institute of Health Stroke Scale, the Brunnstrom Recovery Stage (BRS), the Simple Test for Evaluating Hand Function, and the Functional Independence Measure tests.

Results and Discussion:
Movement counts measured with the wrist accelerometer on the affected upper limb (unilateral accelerometry) over 24 hours and during the 12-hour daytime period (08:00 to 20:00) were significantly correlated with scores for affected upper limb use (the Motor Activity Log) and functions (the upper extremity BRS and the affected side Simple Test for Evaluating Hand Function), upper and lower extremity functions (the National Institute of Health Stroke Scale, the lower extremity BRS, and the motor Functional Independence Measure), and step counts measured over the same period. To estimate the affected upper limb use or disuse, we subtracted the movement counts of the unaffected upper limb from those of the affected upper limb. As a result, the subtracted counts over 24 hours and during the 12-hour daytime period were only related to scores for affected upper limb use and functions.

Conclusions:
Bilateral accelerometry for monitoring upper limb movements in a real-world setting might be useful to clinicians for objective assessment of affected upper limb use or disuse and function among older adults with hemiparesis from acute or subacute stroke.
High-Velocity Quadriceps Exercises Compared to Slow-Velocity Quadriceps Exercises Following Total Knee Arthroplasty: A Randomized Clinical Study
Authors: Doerfler Deborah , Gurney Burke , Mermier Christine , Rauh Mitchell , Black Liza , Andrews Ron 
Published: October 2015

Background and Purpose:
Despite improvement in pain and perceived function in older adults following total knee arthroplasty (TKA), objective outcome measures of muscular impairment and ambulatory function demonstrate significant deficits. Evidence suggests that quadriceps power may play a greater role in ambulatory function than measures of strength alone following TKA. The purpose of this study was to compare the effect of high-velocity (HV) quadriceps exercises with that of slow-velocity (SV) quadriceps exercises on functional outcomes and quadriceps power following TKA.

Methods:
This study was a randomized clinical study conducted in an outpatient physical therapy clinic. Twenty-one participants who were 4 to 6 weeks post unilateral TKA were randomly assigned to an HV or SV group. Participants performed an evidence-based standardized progressive resistance exercise program in addition to HV quadriceps exercises or SV quadriceps exercises. Participants attended 2 sessions per week for 8 weeks. Before and after the 8-week exercise intervention, participants completed a functional questionnaire, health survey, functional testing, and underwent quadriceps strength and power testing.

Results:
Both groups demonstrated improvements in ambulatory outcome measures, strength, speed, and power. The HV group demonstrated significantly greater improvements in distance walked and quadriceps strength than the SV group.

Limitations:
These data should be considered preliminary because of a small sample size.

Conclusion:
HV quadriceps exercises may be an effective rehabilitation strategy in conjunction with a standardized progressive resistance exercise program beginning 4 to 6 weeks after TKA.
Altura, número de folhas, composição química e produção de massa seca de Estilosantes Campo Grande sob níveis de potássio e zinco
Authors: Gomes Françoise Mara , Guimarães Cíntia Gonçalves , Ribeiro Karina Guimarães , Silva Janaína de Lima , Santos Regina Silva , Pereira Odilon Gomes 
Published: October 2015

Objetivou-se determinar a altura de plantas, o número de folhas totais e vivas, a composição química e a produção de massa seca, no primeiro corte e aos 21 dias de rebrota, do estilosantes cv. Campo Grande, sob diferentes níveis de potássio (K2O), com e sem zinco (Zn). O experimento foi realizado em esquema fatorial 4 x 2, no delineamento em blocos casualizados, com quatro repetições. Foram utilizados quatro níveis de K2O (0; 120; 240 e 360 mg/dm3), com e sem Zn (0 e 6 mg/dm3). Não houve efeito da interação níveis de K2O e Zn, nem efeitos independentes de níveis de K2O e de Zn sobre as características estruturais do estilosantes cv. Campo Grande. Os valores médios para altura de plantas, número de folhas totais e número de folhas vivas foram de 21,2 cm, 30,2 folhas e 27,2 folhas vivas, respectivamente. A produção de massa seca não variou com os níveis de K2O e Zn com valor médio de 3,7 g/vaso. Não houve efeito da interação níveis de K2O e Zn, nem efeitos independentes de níveis de K2O e Zn sobre os teores de matéria seca e de fibra em detergente neutro, obtendo-se valores médios de 29,3% e 46,9% MS, respectivamente. No entanto, foi observado efeito da interação níveis de K2O e Zn para os teores de proteína bruta, que apresentaram resposta quadrática. A rebrota aumentou de forma linear com os níveis crescentes de K2O. Embora o mais alto teor de proteína bruta tenha sido obtido nos níveis zero de potássio e zinco, a adubação com potássio é vantajosa por incrementar a rebrota aos 21 dias do estilosantes cv. Campo Grande.
Efeito do ácido fítico e do ferro inorgânico dietéticos na qualidade da carne suina refrigerada
Authors: Monteiro Renilda Terezinha , Silva Caio Abercio , Bridi Ana Maria , Obra Alexandre , Lozano Arturo Pardo , Peres Louise Manha , Novais Aliny Ketilim , Oliveira Eduardo Raele de 
Published: October 2015

O estudo foi conduzido com o objetivo de avaliar o efeito da suplementação do ferro inorgânico e do ácido fítico na dieta de suínos em terminação sobre a qualidade da carne após 24 horas e 7 dias de refrigeração. Foram utilizados 40 suínos machos castrados, na fase de terminação, de genética comercial, com 64,34 ± 6,64 kg de peso médio inicial e 108 dias de idade. Os animais foram pesados e alojados individualmente em baias de alvenaria com área de 3 m2 e piso compacto, onde receberam água e ração à vontade durante o período de 30 dias. O delineamento experimental foi em blocos casualizados, em modelo fatorial 2 x 2, sendo os fatores correspondentes às dietas com e sem ferro inorgânico suplementar (FeI) e com dois níveis de ácido fítico (AF) na ração, alto (4,85%) e baixo (2,98%). Ao atingirem 100,76 ± 6,54 kg de peso médio, os animais foram abatidos, sendo coletadas amostras do músculo longissimus dorsi para análise da qualidade da carne. As amostras foram submetidas às avaliações de pH, cor, marmorização, perda de água por pressão, força de cisalhamento, composição de ferro e oxidação lipídica. Os valores das variáveis avaliadas não foram diferentes entre os fatores, excetuando-se a concentração de ferro no músculo, que foi superior para a dieta com a inclusão de ferro inorgânico. A oxidação lipídica não foi influenciada pela presença ou não do AF e FeI. Os resultados demonstraram que dietas com níveis de AF mais elevados, com ou sem a suplementação de FeI, podem ser utilizadas para suínos em fase de terminação sem prejuízos à qualidade da carne durante a fase de refrigeração
Tratamento do chorume de aterro de resíduos sólidos urbanos utilizando um coagulante à base de Tanino, tratamento biológico e ozonização
Authors: Ribeiro Edir Filipe , Buss Marta Verônica , Menezes Jean Carlo Salomé dos Santos 
Published: October 2015

A crescente produção de resíduos sólidos, demanda a realização de pesquisas visando atenuar os impactos ambientais decorrentes da destinação desses despejos. Sabe-se que as características qualitativas dos resíduos produzidos no Brasil, são predominantemente de origem orgânica, sendo que a pluviosidade causa a geração de grandes volumes de chorume.O presente trabalho teve como objetivo estudar duas diferentes alternativas para o abatimento da carga poluidora do chorume gerado, no aterro sanitário de resíduos sólidos urbanos, localizado em um município do meio oeste de Santa Catarina. Através da caracterização e tratamento por processos biológicos seguido de físico-químicos usando um coagulante a base de tanino e um floculante catiônico de alto peso molecular, a fim de se obterem efluentes com características que permitam o seu descarte de acordo com a legislação. Potencializando a eficiência do processo de tratamento, de forma que, a empresa operadora possa adotar em escala real o processo estudado em laboratório.