bluuebunny/crossref_metadata_2025_split huggingface dataset:
Penyimpangan HAM Menuju Politik Identitas
Authors: Pattiserlihun Selvone Christin 
Published: August 2024

Abstrak
Pelanggaran HAM terhadap perempuan dan anak di ruang Kebebasan Beragama dan Berkeyakinan (KBB) Indonesia nampak dalam ruang-ruang publik. Tulisan ini berfokus pada kasus-kasus yang marak terjadi dalam masyarakat multikultural. Tulisan ini bertujuan untuk mengidentifikasi, mendiskusikan, dan menanggapi pelanggaran HAM dalam bentuk pelarangan dan pemaksaan busana keagamaan di sekolah umum yang berdampak pada pengembangan politik identitas di Indonesia. Metode yang digunakan adalah studi kasus ganda kualitatif yang akan membahas dan membandingkan beberapa kasus pelanggaran HAM pada busana keagamaan anak di sekolah umum dengan menggunakan media online, dan kajian literatur regulasi sebagai sumber data. Hasil penelitian ini menunjukkan empat temuan yakni pertama, pemaksaan penggunaan busana keagamaan terjadi di wilayah mayoritas muslim. Sedangkan pelarangan penggunaan busana keagamaan terjadi di wilayah mayoritas non muslim. Kedua, penetapan regulasi busana keagamaan bagi lembaga pendidikan pada wilayah tertentu masih berdasar pada mayoritas keagamaan wilayah terkait. Ketiga, kontestasi busana keagamaan berdampak pada ganguan psikological, fisikal, dan relasional korban. Keempat, kontestasi budaya merupakan sarana melanggengkan politik identitas dan menyasar kelompok rentan seperti perempuan dan anak. Dengan demikian, negara memiliki tugas besar untuk menjamin kebebasan beragama dalam ruang-ruang rentan.
PENGARUH BOBOT DAY OLD CHICK YANG BERBEDA TERHADAP PENAMPILAN PRODUKSI, PERSENTASE KARKAS, INDEKS PERFORMA, INCOME OVER FEED COST, DAN NILAI EKONOMIS PAKAN BROILER
Authors: Yulianti Dyah Lestari , Sinaga Ruth Rodearni , Gultom Ariel Nickholas , Ma’arif Muhammad Wahyu Agung 
Published: August 2024

Penelitian ini bertujuan untuk mengetahui pengaruh bobot Day Old Chick (DOC) yang berbeda terhadap penampilan produksi, persentase karkas, Indeks Performa (IP) Income Over Feed Cost (IOFC), dan nilai ekonomis pakan broiler. Materi penelitian adalah 75 ekor DOC strain Lohmann tidak dibedakan jenis kelamin. Pakan basal adalah pakan komersial broiler fase starter produksi PT. Charoen Pokphand Indonesia kode BR1. DOC dipelihara secara intensif selama 35 hari pada tipe kandang terbuka. Metode penelitian adalah percobaan dengan Rancangan Acak Lengkap 3 perlakuan, 5 ulangan. Satu unit percobaan terdiri dari 5 ekor DOC. Perlakuan penelitian adalah bobot DOC; P1=41-43 g, P2=44-46 g, dan P3=47-49 g. Variabel penelitian adalah konsumsi pakan, pertambahan bobot badan, bobot panen, persentase karkas, persentase potongan karkas, IP, IOFC, dan nilai ekonomis pakan Data yang diperoleh ditabulasi dan dilakukan menggunakan analisis statistic sidik ragam (ANOVA), jika terdapat perbedaan antar perlakuan dilanjutkan dengan uji Duncan’s. Hasil analisis statistik menunjukkan tidak terdapat pengaruh bobot DOC yang berbeda terhadap penampilan produksi (konsumsi pakan, pertambahan bobot badan, dan bobot panen), persentase karkas dan persentase potongan karkas, IP, IOFC, dan nilai ekonomis pakan (P>0.05). Bobot DOC dengan rentang 41-49 g pada pemeliharaan di kandang tipe terbuka tidak memberikan pengaruh terhadap penampilan produksi dan parameter ekonomi. Disarankan untuk melakukan penelitian lebih lanjut tentang pengaruh parameter fisik DOC lain terhadap penampilan produksi broiler.
WATCHING ENGLISH MOVIE ON IMPROVING STUDENTS' WRITING ABILITY
Authors: Forsia Lastry 
Published: August 2024

This research aims to investigate whether there is a significant effect of watching English movie on improving studentsâ€™ ability to write a narrative text at the tenth-grade students. This research used quasi experimental method. Sample of the study consisted of 76 students. The sampling technique was used random sampling. In this research, the researcher used to watch English movie to improve studentsâ€™ writing ability to trigger ideas. This research consisted of three stages. The first stage was pre-test giving stage. The second was treatment implementation stage, namely watching English movie as a technique in experiment class and without watching English movie in controlled class. The third was post-test giving stage. The type of the research was written test. To validate the instrument, the writer asked an expert to validate its content. This instrument was said valid. Then, the results of both classes were analyzed by using t-test. The study findings revealed that there were significant differences between the mean scores attained by the experimental class and control class. Post intervention data indicated a remarkable increase in the experimental classâ€™ achievement in writing ability with the result found that tobserved > ttable for the significant level (0,025), 2,72 > 2. So, Ho is rejected, and Ha is accepeted. It means that there is significant effect of watching English movie on improving studentsâ€™ ability to write a narrative text at the tenth grade of SMAN 12 Kabupaten Tangerang in academic year 2021/2022
IMPLEMENTATION PICTURE AND PICTURE STRATEGY TO INCREASE STUDENTS' ABILITY IN VOCABULARY AT MAN 3 MEDAN
Authors: Pasaribu Gumarpi Rahis , Daulay Sholihatul Hamidah , Saragih Zainuddin 
Published: August 2024

This research was intended to find out the empirical evidence of studentsâ€™ ability in vocabulary by using picture and picture strategy in class X of Man 3 Medan. The method used in this research was Classroom Action Research (CAR) method in which to identify and to solve the problem on the studentsâ€™ ability in vocabulary. The result of the data analyzing showed that there was an increasing on the studentsâ€™ ability in vocabulary through picture and picture strategy. It was showed from the mean of pre â€“ test was 31,62. After picture and picture strategy was applied in the first cycle there was an increase of the studentsâ€™ mean score which was 53,22 and for the second cycle after reflection on the first cycle, there was an increase of students mean score which 92,25. Moreover, post â€“ test I session which was 19,35% (6 students) who got point of 70. In post â€“ test II for the second cycle which was 90,32 % (28 students) who got the point of over 70. It was found that the teaching vocabulary by picture and picture strategy could increase the studentsâ€™ ability in vocabulary.
Perbandingan Morfometrik Sistem Pencernaan Ikan Lele (Clarias batrachus), Ikan Nila (Oreochromis niloticus), dan Ikan Kembung (Rastrelliger sp.)
Authors: Malini Desak Made , Putri Deviana Aulia 
Published: August 2024

Ikan memiliki keragaman habitat dan jenis makanan yang dikonsumsinya, sehingga mengakibatkan adanya perbedaan di antara spesiesnya terutama pada morfologi dan morfometrik organ dalam tubuhnya. Salah satu bagian dari ikan yang memiliki perbedaan cukup signifikan yaitu pada sistem pencernaan. Adanya perbedaan tersebut menjadikan ikan dapat mengefisiensikan pencernaannya agar sesuai dengan kondisi lingkungan dan jenis makanan yang dikonsumsinya, sehingga dapat memastikan kelangsungan hidup dan reproduksinya akan lebih baik. Tujuan penelitian untuk membandingkan morfometrik pada organ sistem pencernaan dari ikan lele (Clarias batrachus), ikan nila (Oreochromis niloticus), dan ikan kembung (Rastrelliger sp.). Tahapan penelitian meliputi pengambilan sampel, preparasi anatomi ikan, pengukuran berat dan panjang organ pencernaan, pengukuran Gastro Somatic Index (GaSI), pengukuran Intestine Somatic Index (ISI), pengukuran Gut Lengths (RGL), pengukuran Relative Intestine Lengths (RIL), dan pengukuran Hepatosomatic Index (HSI). Analisis menggunakan varian satu arah (oneway Anova) dengan memanfaatkan Software Statistical Package for the Social Sciences (SPSS) 22 dan uji jarak berganda duncan. Hasil penelitian menunjukkan bahwa nilai GaSI, RGL, RIL, dan HSI dari ketiga spesies ikan berbeda secara signifikan, sedangkan nilai ISI tidak berbeda nyata. Disimpulkan bahwa terdapat perbedaan morfometrik pada organ sistem pencernaan dari ikan nila, ikan kembung, dan ikan lele.
Penyuluhan TB Paru Resisten Obat Pada Siswa SMA 2 di Kota Luwuk Kabupaten Banggai
Authors: Subchan Djadid , Mangemba Dg. 
Published: August 2024

Tuberculosis is a direct infectious disease transmitted through the air caused by Mycobacterium Tuberculosis. TB is a health problem that has existed since 5000 years ago but is still developing today. TB is the 10th disease that is the biggest cause of death throughout the world. In fact, based on the latest WHO data, TB cases in Indonesia are ranked second after India with an estimated 969,000 cases and 144 thousand deaths per year (WHO, 2023). Based on WHO estimates in the 2020 Global TB Report, drug-resistant TB cases in Indonesia are estimated to be 2.4% of new patients seeking treatment/discovered. For old sufferers, according to estimates, there are 13% of drug resistan TB sufferers. With a total of around 24,000 cases or an incidence of 8.8/100,000 population. The aim of community service is to provide understanding to teenagers that pulmonary TB needs to be prevented, especially RO pulmonary TB which is more complicated to treat. Community service activities were held on October 16 2023 at SMAN II Luwuk with 88 students participating. The method used is counseling with lectures and questions and answers. Previously a pre-test was given and after counseling a post-test was carried out. The results of the counseling by comparing the pre-test and post-test showed an increase in knowledge. It is hoped that education about RO TB can be encouraged by health education institutions, the Health Service and other parties, considering the greater danger to public health.
Biomechanical optimization of the magnesium alloy bionic cannulated screw for stabilizing femoral neck fractures: a finite element analysis
Authors: Cui Yunwei , Ding Kai , Lv Hongzhi , Cheng Xiaodong , Fan Zixi , Sun Dacheng , Zhang Yifan , Chen Wei , Zhang Yingze 
Published: August 2024

PurposesThe magnesium alloy bionic cannulated screw (MABCS) was designed in a previous study promoting cortical–cancellous biphasic healing of femoral neck fractures. The main purpose was to analyze the bore diameters that satisfy the torsion standards and further analyze the optimal pore and implantation direction for stabilizing femoral neck fractures.MethodsThe MABCS design with bionic holes with a screw diameter of less than 20% met the torsion standard for metal screws. The MABCS was utilized to repair the femoral neck fracture via Abaqus 6.14 software, which simulated the various stages of fracture healing to identify the optimal biomechanical environment for bionic hole size (5%, 10%, 15%, and 20%) and implantation direction (0°, 45°, 90°, and 135°).ResultsThe stress distribution of the MABCS fracture fixation model is significantly improved with an implantation orientation of 90°. The MABCS with a bionic hole and a screw diameter of 10% provides optimal stress distribution compared with the bionic cannulated screw with diameters of 5%, 15%, and 20%. In addition, the cannulated screw fixation model with a 10% bionic hole size has optimal bone stress distribution and better internal fixation than the MABCS fixation models with 5%, 15%, and 20% screw diameters.ConclusionIn summary, the MABCS with 10% screw diameter bionic holes has favorable biomechanical characteristics for stabilizing femoral neck fractures. This study provides a biomechanical foundation for further optimization of the bionic cannulated screw.
Language abilities and phonological information processing mediate the association of spelling with bilingualism and socioeconomic status
Authors: Schöfl Martin , Weber Christoph , Steinmair Gabriele , Zepnik Sabine , Grimm Angela 
Published: August 2024

IntroductionResearch to date has focused on the associations between spelling and (i) its precursors (phonological information processing and language) and (ii) socioeconomic status and bilingualism. Studies have also indicated that bilingualism and parental education are associated with spelling precursors. Whereas these associations have previously been analyzed individually, this study proposes a mediation model in which the effects of socioeconomic status and bilingualism on spelling are mediated by phonological information processing and language skills.MethodsA total of 1,012 German-speaking first graders attending primary schools in Austria were assessed at the beginning of the first grade on their phonological information processing and language abilities, and their spelling abilities were tested again at the end of the first grade. Subsequently, a structural equation modeling approach was employed to evaluate the mediation model.ResultsIn line with the mediation hypothesis, the results show indirect effects of parental education (as a measure of socioeconomic status) on spelling via language and phonological information processing. In addition to mediation, we also found a direct effect of SES on spelling performances. For bilingualism, the results support full mediation as an indirect effect via language abilities. Notably, we found no effect of bilingual status on phonological information processing.DiscussionThis study highlights the ongoing need for systematic oral language training for bilingual children and children from low-SES backgrounds that starts in preschool and continues throughout primary school. Moreover, given the predictive effect of phonological awareness on spelling achievement, phonological awareness should be part of the training for preschool and school-aged children.
Association between serum transferrin saturation levels and heart failure in adults aged ≥40 years: a cross-sectional study based on NHANES (2017-2020.03)
Authors: Wang Mian , Zhang Dongyang , Jiang Lanying , Ye Maosheng , Nie Jing , Yin Junjie 
Published: August 2024

BackgroundLimited data are available regarding the association between serum transferrin saturation (TSAT) levels and heart failure (HF).MethodsWe utilized data from National Health and Nutrition Examination Survey (NHANES) 2017- 2020.03 for analysis. Data on TAST, HF and covariates were extracted and analyzed. Weighted logistic regression and subgroup analysis were used to explore the independent association between TSAT and HF. Furthermore, interaction tests were also carried out to evaluate the strata differences. We subsequently assessed whether there was a non-linear relationship between the 2 using Restricted cubic spline (RCS) and threshold effect models.ResultA total of 282 (3.87%) participants were identified to have HF. Among the total population, participants with HF had significantly lower TSAT levels compared to those without HF (24.63 vs. 27.95, P = 0.001). After fully adjusting for potential confounders, weighted multiple logistic regression models revealed a 2.6% reduced in the risk of HF when each unit of TSAT increased. There was also a negative association between elevated TSAT and developed risk of HF in the quartile groups (Q1 OR:1.00; Q2 OR: 0.924 [95%CI:0.593,1.440]; Q3 OR: 0.515 [95%CI:0.298,0.891]; Q4 OR:0.411 [95%CI:0.201,0.839]). The subgroup analysis results remained consistent across strata, with a strong negative correlation between TSAT and HF. Interaction tests showed no dependence on gender, age, Body Mass Index, race, diabetes, hypertension, hyperlipidemia, ratio of family income to poverty and education for this negative association between TSAT and HF (all p for interaction &gt;0.05). The RCS and threshold effect models indicated a linear negative correlation between TSAT and HF, which was more pronounced when TSAT under 40%.ConclusionOverall, these findings suggest a consistent and negative association between TSAT levels and the presence of HF among middle-aged and older adults in the United States.
Association between nontraditional lipid parameters and the risk of type 2 diabetes and prediabetes in patients with nonalcoholic fatty liver disease: from the national health and nutrition examination survey 2017–2020
Authors: Liu Jierui , Fu Qingan , Su Ruolin , Liu Rixiang , Wu Shisheng , Li Ke , Wu Jianhua , Zhang Nuobei 
Published: August 2024

BackgroundNonalcoholic fatty liver disease (NAFLD) is a prevalent metabolic disorder strongly linked to type 2 diabetes mellitus (T2DM). Understanding the predictive value of lipid parameters in identifying abnormal glucose metabolism in NAFLD patients is crucial for early intervention.MethodsThis study analyzed data from the National Health and Nutrition Examination Survey(NHANES) database (2017-2020) involving 1066 NAFLD patients. Participants were categorized into three groups: T2DM (n=414), prediabetes mellitus (pre-DM) (n=507), and normoglycemia (NG) (n=145). Traditional lipid parameters [triglycerides (TG) and high-density lipoprotein cholesterol (HDL-C)] and nontraditional lipid parameters [atherogenic index of plasma (AIP), residual cholesterol (RC), and non-high-density lipoprotein cholesterol (non-HDL-C)] were evaluated for their association with T2DM and pre-DM.ResultsElevated TG levels were significantly associated with an increased risk of T2DM and pre-DM, whereas high HDL-C demonstrated a protective effect. Among nontraditional lipid parameters, increased AIP and RC were most strongly associated with T2DM risk, while high non-HDL-C was best associated with the development of pre-DM. Stratified analyses revealed that these associations were stronger in younger, non-obese, smoking, and female NAFLD patients.ConclusionNontraditional lipid parameters, particularly AIP and RC, show superior predictive value over traditional lipid parameters in identifying abnormal glucose metabolism in NAFLD patients. Incorporating these novel biomarkers into clinical practice could enhance early detection and prevention strategies for T2DM and pre-DM in this high-risk population.
Causal role of gut microbiota, serum metabolites, immunophenotypes in myocarditis: a mendelian randomization study
Authors: Li Kaiyuan , Liu Peng , Wang Xiuqi , Zheng Zhipeng , Liu Miao , Ye Jun , Zhu Li 
Published: August 2024

BackgroundThe intricate relationship among gut microbiota, serum metabolites, and immunophenotypes may significantly impact myocarditis. However, direct causal links between these domains and myocarditis are not well understood.MethodsThe study performed Mendelian randomization (MR) analysis using genetic data from public sources. Exposure data included 211 gut microbiota, 486 serum metabolites, and 731 immunophenotypes from Mibiogen, the Metabolomics GWAS server, and GWAS catalog databases. Single nucleotide polymorphisms (SNPs) were selected as instrumental variables based on established criteria. Myocarditis data from GWAS (427,911 participants, 24, 180, 570 SNPs) were used as the outcome variable. MR analysis was conducted using Inverse Variance Weighting (IVW), with Cochran’s Q test for heterogeneity and Egger’s intercept to assess horizontal pleiotropy.Results9 gut microbiota, 10 serum metabolites, and 2 immunophenotypes were negatively associated with myocarditis risk. In contrast, 5 gut microbiota, 12 serum metabolites, and 7 immunophenotypes were positively associated with myocarditis risk (all, P &lt; 0.05). Sensitivity analyses confirmed the stability of these results.ConclusionThis MR study suggests that gut microbiota, serum metabolites, and immunophenotypes may causally influence myocarditis risk. These findings provide genetic evidence for myocarditis etiology and could inform future precision prevention and treatment strategies.
Exome sequence analysis identifies a homozygous, pathogenic, frameshift variant in the MAN2B1 gene underlying clinical variant of α-mannosidosis
Authors: Hashmi Jamil Amjad , Latif Muhammad , Balahmar Reham M. , Ali Muhammad Zeeshan , Alfadhli Fatima , Khan Muzammil Ahmad , Basit Sulman 
Published: August 2024

Backgroundα-mannosidosis (MAN) is a rare genetic condition that segregates in an autosomal recessive manner. Lack of lysosomal alpha-mannosidase is the underlying cause of the disease. Symptoms of the disease gradually worsen with the age. Newborns are usually asymptomatic, however, some cases are reported with either congenital ankle equinus or hydrocephalus during the first year. Primary symptoms are characterized by immune deficiency, hearing loss, skeletal abnormalities, progressive mental, motor and speech functions’ impairment followed by facial asymmetry.MethodsWe studied two Saudi families (A and B) with bilateral moderate hearing loss (family A) and clubfoot with glaucoma (family B). Clinical diagnosis was not reached based on phenotype of patients. Therefore, hypothesis-free whole exome sequencing (WES) was performed on DNA samples from affected individuals of both the families, followed by Sanger sequencing and segregation analysis to validate the segregation of the identified variant. Furthermore, 3D protein modelling was performed to determine the in silico effects of the identified variant on the protein structure and function.ResultsRe-examination of clinical features revealed that the patients in family A have speech delay and hearing impairment along with craniostenosis, whereas the patients from family B have only clubfoot and glaucoma. WES identified a well known pathogenic homozygous frameshift variant (NM_000528.4: c.2402dupG; p.S802fs*129) in MAN2B1 in both the families. Sanger sequencing confirmed the segregation of the variant with the disease phenotype in both the families. 3D structural modeling of the MAN2B1 protein revealed significant changes in the tertiary structure of the mutant protein, which would affect enzyme function. This report presents a new case where partial and novel α-mannosidosis phenotypes are associated with a MAN2B1 gene pathogenic variant.ConclusionPatients in both the families have manifested peculiar set of clinical symptoms associated with α-mannosidosis. Family A manifested partial clinical symptoms missing several characteristic features like intellectual disability, dysmorphic features, neurological and abdominal manifestations, whereas family B has no reported clinical symptoms related to α-mannosidosis except the novel symptoms including club foot and glaucoma which has never been reported earlier The current findings support the evidence that biallelic variants of MAN2B1 are associated with new clinical variants of α-mannosidosis.
TGF-β1 overexpression in severe COVID-19 survivors and its implications for early-phase fibrotic abnormalities and long-term functional impairment
Authors: Alfaro Enrique , Casitas Raquel , Díaz-García Elena , García-Tovar Sara , Galera Raúl , Torres-Vargas María , Fernández-Velilla María , López-Fernández Cristina , Añón José M. , Quintana-Díaz Manuel , García-Río Francisco , Cubillos-Zapata Carolina 
Published: August 2024

IntroductionIn post-COVID survivors, transforming growth factor-beta-1 (TGF-β1) might mediate fibroblast activation, resulting in persistent fibrosis.MethodsIn this study, 82 survivors of COVID-19-associated ARDS were examined at 6- and 24-months post-ICU discharge. At 6-months, quantitative CT analysis of lung attenuation was performed and active TGF-β1 was measured in blood and exhaled breath condensate (EBC).ResultsAt 6-months of ICU-discharge, patients with reduced DmCO/alveolar volume ratio exhibited higher plasma and EBC levels of active TGF-β1. Plasma TGF-β1 levels were elevated in dyspneic survivors and directly related to the high-attenuation lung volume. In vitro, plasma and EBC from survivors induced profibrotic changes in human primary fibroblasts in a TGF-β receptor-dependent manner. Finally, at 6-months, plasma and EBC active TGF-β1 levels discriminated patients who, 24-months post-ICU-discharge, developed gas exchange impairment.DiscussionTGF-β1 pathway plays a pivotal role in the early-phase fibrotic abnormalities in COVID-19-induced ARDS survivors, with significant implications for long-term functional impairment.