bluuebunny/crossref_metadata_2025_split huggingface dataset:
The crypsis hypothesis explained: a reply to Jayasuriya et al. (2015)
Authors: Paulsen Torbjørn R. , Colville Louise , Daws Matthew I. , Eliassen Sigrunn , Högstedt Göran , Kranner Ilse , Thompson Ken , Vandvik Vigdis 
Published: August 2015

AbstractIn imbibing seeds, resumption of metabolism leads to the unavoidable release of volatile by-products that are perceived as cues by rodent seed predators. The crypsis hypothesis proposes that the primary function of a water-impermeable, hard seed coat is to reduce rodent seed predation by rendering seeds olfactorily cryptic. In an opinion paper, Jayasuriya et al. (2015) find the crypsis hypothesis unscientific and ‘not consistent with Darwin's theory of evolution by natural selection’. It is unfortunate that Jayasuriya et al. (2015) did not appreciate that the crypsis hypothesis offers an alternative explanation for the evolution of water-impermeable seeds: released seed volatiles are cues used by rodents to locate seeds, and variation in seed-coat permeability leading to differences in seed volatile release represents the variable under selection. Furthermore, the sealing of water-impermeable seed coats imposes a cost of increased generation time and, therefore, dormancy-release mechanisms are expected to subsequently evolve in response to local environmental conditions. We also disagree with most other claims by Jayasuriya et al. (2015), who failed to appreciate how species with dimorphic seeds – one morph with permeable and the other with impermeable seed coats – benefit from rodent caching behaviour and population dynamics. We welcome this opportunity to clarify and elaborate on key features and the evolution of water-impermeable seed coats according to the crypsis hypothesis.
Estimating usual intakes mainly affects the micronutrient distribution among infants, toddlers and pre-schoolers from the 2012 Mexican National Health and Nutrition Survey
Authors: Piernas Carmen , Miles Donna R , Deming Denise M , Reidy Kathleen C , Popkin Barry M 
Published: August 2015

AbstractObjectiveTo compare estimates from one day with usual intake estimates to evaluate how the adjustment for within-person variability affected nutrient intake and adequacy in Mexican children.DesignIn order to obtain usual nutrient intakes, the National Cancer Institute’s method was used to correct the first 24 h dietary recall collected in the entire sample (n 2045) with a second 24 h recall collected in a sub-sample (n 178). We computed estimates of one-day and usual intakes of total energy, fat, Fe, Zn and Na.Setting2012 Mexican National Health and Nutrition Survey.SubjectsA total of 2045 children were included: 0–5·9 months old (n 182), 6–11·9 months old (n 228), 12–23·9 months old (n 537) and 24–47·9 months old (n 1098). From these, 178 provided an additional dietary recall.ResultsAlthough we found small or no differences in energy intake (kJ/d and kcal/d) between one-day v. usual intake means, the prevalence of inadequate and excessive energy intake decreased somewhat when using measures of usual intake relative to one day. Mean fat intake (g/d) was not different between one-day and usual intake among children >6 months old, but the prevalence of inadequate and excessive fat intake was overestimated among toddlers and pre-schoolers when using one-day intake (P<0·05). Compared with usual intake, estimates from one day yielded overestimated prevalences of inadequate micronutrient intakes but underestimated prevalences of excessive intakes among children aged >6 months.ConclusionsThere was overall low variability in energy and fat intakes but higher for micronutrients. Because the usual intake distributions are narrower, the prevalence of inadequate/excessive intakes may be biased when estimating nutrient adequacy if one day of data is used.
Formulating policy activities to promote healthy and sustainable diets
Authors: Lawrence Mark A , Friel Sharon , Wingrove Kate , James Sarah W , Candy Seona 
Published: August 2015

AbstractObjectiveTo develop a policy formulation tool for strategically informing food and nutrition policy activities to promote healthy and sustainable diets (HSD).DesignA policy formulation tool consisting of two complementary components was developed. First, a conceptual framework of the environment–public health nutrition relationship was constructed to characterise and conceptualise the food system problem. Second, an ‘Orders of Food Systems Change’ schema drawing on systems dynamics thinking was developed to identify, assess and propose policy options to redesign food systems.SettingFood and nutrition policy activities to promote HSD have been politicised, fragmented and lacking a coherent conceptual and strategic focus to tackle complex food system challenges.ResultsThe tool’s conceptual framework component comprises three integrated dimensions: (i) a structure built around the environment and public health nutrition relationship that is mediated via the food system; (ii) internal mechanisms that operate through system dynamics; and (iii) external interactions that frame its nature and a scope within ecological parameters. The accompanying schema is structured around three orders of change distinguished by contrasting ideological perspectives on the type and extent of change needed to ‘solve’ the HSD problem.ConclusionsThe conceptual framework’s systems analysis of the environment–public health nutrition relationship sets out the food system challenges for HSD. The schema helps account for political realities in policy making and is a key link to operationalise the framework’s concepts to actions aimed at redesigning food systems. In combination they provide a policy formulation tool to strategically inform policy activities to redesign food systems and promote HSD.
PARAMETRIZING ELLIPTIC CURVES BY MODULAR UNITS
Authors: BRUNAULT FRANÇOIS 
Published: August 2015

It is well known that every elliptic curve over the rationals admits a parametrization by means of modular functions. In this short note, we show that only finitely many elliptic curves over $\mathbf{Q}$ can be parametrized by modular units. This answers a question raised by W. Zudilin in a recent work on Mahler measures. Further, we give the list of all elliptic curves $E$ of conductor up to 1000 parametrized by modular units supported in the rational torsion subgroup of $E$. Finally, we raise several open questions.
Adapting brief Behavioural Activation (BA) for adolescent depression: a case example
Authors: Pass Laura , Brisco Gemma , Reynolds Shirley 
Published: August 2015

AbstractThere is an increasing evidence base for the effectiveness of Behavioural Activation in treating adult depression; however, there has been little investigation of using this approach with adolescents. This article reports on the adaptation of brief Behavioural Activation for Depression (BATD) for adolescents (BATD-A). A case study is reported to illustrate the brief structured approach, treatment response as indicated by routine outcome measures, and the family's view of the intervention. The adaptations made to the adult BATD manual are discussed including parental input, adapted values and activities, and engagement issues. It is hoped that following further evaluation, BATD-A could be successfully delivered as a low-intensity intervention for depression.
EARLY STRUCTURAL REASONING. GENTZEN 1932
Authors: MORICONI ENRICO 
Published: August 2015

AbstractThis paper is a study of the opening section of Gentzen’s first publication of 1932,Über die Existenz unabhängiger Axiomensysteme zu unendlichen Satzsystemen, a text which shows the relevance of Hertz’s work of the 1920’s for the young Gentzen. In fact, Gentzen borrowed from Hertz the analysis of the notion of consequence, which was given in terms of the rules of thinning (Verdünnung) and cut (Schnitt) on sequents (there called “sentences”(Sätze)). Moreover, following Hertz again, he also judged it necessary to justify the forms of inference of the system by providing a semantics for them, so that it became possible to make precise the informal notion of consequence, and to show that the inference rules adopted are correct and sufficient.
The Paradoxical Religiosity Effect: Religion and Politics in Indonesia and the United States
Authors: Sumaktoyo Nathanael Gratias , Ottati Victor , Untoro Vinaya 
Published: August 2015

AbstractWe argue that personal religiosity and political religiosity are distinct attributes of a political candidate. Personal religiosity reflects a candidate's level of personal religious commitment and political religiosity reflects the candidate's policy regarding separating versus blending religion and politics. The paradoxical religiosity hypothesis predicts that, within a democracy, personal religiosity will increase voters' endorsement of a candidate whereas political religiosity will decrease voters' endorsement. We test this hypothesis comparatively in two experiments, one performed within a long-standing democracy containing predominantly Christian voters (the United States), and the other within a more recent democracy containing predominantly Muslim voters (Indonesia). We demonstrate the robustness of the paradoxical religiosity effect and its persistence across the two countries, suggesting that Muslim Indonesians are no less capable than Christian Americans in separating the sacred and the secular.
Systematic chromatin state comparison of epigenomes associated with diverse properties including sex and tissue type
Authors: Yen Angela , Kellis Manolis 
Published: August 2015

AbstractEpigenomic data sets provide critical information about the dynamic role of chromatin states in gene regulation, but a key question of how chromatin state segmentations vary under different conditions across the genome has remained unaddressed. Here we present ChromDiff, a group-wise chromatin state comparison method that generates an information-theoretic representation of epigenomes and corrects for external covariate factors to better isolate relevant chromatin state changes. By applying ChromDiff to the 127 epigenomes from the Roadmap Epigenomics and ENCODE projects, we provide novel group-wise comparative analyses across sex, tissue type, state and developmental age. Remarkably, we find that distinct sets of epigenomic features are maximally discriminative for different group-wise comparisons, in each case revealing distinct enriched pathways, many of which do not show gene expression differences. Our methodology should be broadly applicable for epigenomic comparisons and provides a powerful new tool for studying chromatin state differences at the genome scale.
The molecular mechanism of Zinc acquisition by the neisserial outer-membrane transporter ZnuD
Authors: Calmettes Charles , Ing Christopher , Buckwalter Carolyn M. , El Bakkouri Majida , Chieh-Lin Lai Christine , Pogoutse Anastassia , Gray-Owen Scott D. , Pomès Régis , Moraes Trevor F. 
Published: August 2015

AbstractInvading bacteria from the Neisseriaceae, Acinetobacteriaceae, Bordetellaceae and Moraxellaceae families express the conserved outer-membrane zinc transporter zinc-uptake component D (ZnuD) to overcome nutritional restriction imposed by the host organism during infection. Here we demonstrate that ZnuD is required for efficient systemic infections by the causative agent of bacterial meningitis, Neisseria meningitidis, in a mouse model. We also combine X-ray crystallography and molecular dynamics simulations to gain insight into the mechanism of zinc recognition and transport across the bacterial outer-membrane by ZnuD. Because ZnuD is also considered a promising vaccine candidate against N. meningitidis, we use several ZnuD structural intermediates to map potential antigenic epitopes, and propose a mechanism by which ZnuD can maintain high sequence conservation yet avoid immune recognition by altering the conformation of surface-exposed loops.
Reversible heart rhythm complexity impairment in patients with primary aldosteronism
Authors: Lin Yen-Hung , Wu Vin-Cent , Lo Men-Tzung , Wu Xue-Ming , Hung Chi-Sheng , Wu Kwan-Dun , Lin Chen , Ho Yi-Lwun , Stowasser Michael , Peng Chung-Kang 
Published: August 2015

AbstractExcess aldosterone secretion in patients with primary aldosteronism (PA) impairs their cardiovascular system. Heart rhythm complexity analysis, derived from heart rate variability (HRV), is a powerful tool to quantify the complex regulatory dynamics of human physiology. We prospectively analyzed 20 patients with aldosterone producing adenoma (APA) that underwent adrenalectomy and 25 patients with essential hypertension (EH). The heart rate data were analyzed by conventional HRV and heart rhythm complexity analysis including detrended fluctuation analysis (DFA) and multiscale entropy (MSE). We found APA patients had significantly decreased DFAα2 on DFA analysis and decreased area 1–5, area 6–15 and area 6–20 on MSE analysis (all p < 0.05). Area 1–5, area 6–15, area 6–20 in the MSE study correlated significantly with log-transformed renin activity and log-transformed aldosterone-renin ratio (all p < = 0.01). The conventional HRV parameters were comparable between PA and EH patients. After adrenalectomy, all the altered DFA and MSE parameters improved significantly (all p < 0.05). The conventional HRV parameters did not change. Our result suggested that heart rhythm complexity is impaired in APA patients and this is at least partially reversed by adrenalectomy.
Enzyme replacement in the CSF to treat metachromatic leukodystrophy in mouse model using single intracerebroventricular injection of self-complementary AAV1 vector
Authors: Hironaka Kohei , Yamazaki Yoshiyuki , Hirai Yukihiko , Yamamoto Motoko , Miyake Noriko , Miyake Koichi , Okada Takashi , Morita Akio , Shimada Takashi 
Published: August 2015

AbstractMetachromatic leukodystrophy (MLD) is a lysosomal storage disease caused by a functional deficiency in human arylsulfatase A (hASA). We recently reported that ependymal cells and the choroid plexus are selectively transduced by intracerebroventricular (ICV) injection of adeno-associated virus serotype 1 (AAV1) vector and serve as a biological reservoir for the secretion of lysosomal enzymes into the cerebrospinal fluid (CSF). In the present study, we examined the feasibility of this AAV-mediated gene therapy to treat MLD model mice. Preliminary experiments showed that the hASA level in the CSF after ICV injection of self-complementary (sc) AAV1 was much higher than in mice injected with single-stranded AAV1 or scAAV9. However, when 18-week-old MLD mice were treated with ICV injection of scAAV1, the concentration of hASA in the CSF gradually decreased and was not detectable at 12 weeks after injection, probably due to the development of anti-hASA antibodies. As a result, the sulfatide levels in brain tissues of treated MLD mice were only slightly reduced compared with those of untreated MLD mice. These results suggest that this approach is potentially promising for treating MLD, but that controlling the immune response appears to be crucial for long-term expression of therapeutic proteins in the CSF.
Lattice Strain Mapping of Platinum Nanoparticles on Carbon and SnO2 Supports
Authors: Daio Takeshi , Staykov Aleksandar , Guo Limin , Liu Jianfeng , Tanaka Masaki , Matthew Lyth Stephen , Sasaki Kazunari 
Published: August 2015

AbstractIt is extremely important to understand the properties of supported metal nanoparticles at the atomic scale. In particular, visualizing the interaction between nanoparticle and support, as well as the strain distribution within the particle is highly desirable. Lattice strain can affect catalytic activity and therefore strain engineering via e.g. synthesis of core-shell nanoparticles or compositional segregation has been intensively studied. However, substrate-induced lattice strain has yet to be visualized directly. In this study, platinum nanoparticles decorated on graphitized carbon or tin oxide supports are investigated using spherical aberration-corrected scanning transmission electron microscopy (Cs-corrected STEM) coupled with geometric phase analysis (GPA). Local changes in lattice parameter are observed within the Pt nanoparticles and the strain distribution is mapped. This reveals that Pt nanoparticles on SnO2 are more highly strained than on carbon, especially in the region of atomic steps in the SnO2 lattice. These substrate-induced strain effects are also reproduced in density functional theory simulations and related to catalytic oxygen reduction reaction activity. This study suggests that tailoring the catalytic activity of electrocatalyst nanoparticles via the strong metal-support interaction (SMSI) is possible. This technique also provides an experimental platform for improving our understanding of nanoparticles at the atomic scale.
Increasing Boiling Heat Transfer using Low Conductivity Materials
Authors: Rahman Md Mahamudur , Pollack Jordan , McCarthy Matthew 
Published: August 2015

AbstractWe report the counterintuitive mechanism of increasing boiling heat transfer by incorporating low-conductivity materials at the interface between the surface and fluid. By embedding an array of non-conductive lines into a high-conductivity substrate, in-plane variations in the local surface temperature are created. During boiling the surface temperature varies spatially across the substrate, alternating between high and low values and promotes the organization of distinct liquid and vapor flows. By systematically tuning the peak-to-peak wavelength of this spatial temperature variation, a resonance-like effect is seen at a value equal to the capillary length of the fluid. Replacing ~18% of the surface with a non-conductive epoxy results in a greater than 5x increase in heat transfer rate at a given superheat temperature. This drastic and counterintuitive increase is shown to be due to optimized bubble dynamics, where ordered pathways allow for efficient removal of vapor and the return of replenishing liquid. The use of engineered thermal gradients represents a potentially disruptive approach to create high-efficiency and high-heat-flux boiling surfaces which are naturally insensitive to fouling and degradation as compared to other approaches.
Experimental Demonstration of Underwater Acoustic Scattering Cancellation
Authors: Rohde Charles A. , Martin Theodore P. , Guild Matthew D. , Layman Christopher N. , Naify Christina J. , Nicholas Michael , Thangawng Abel L. , Calvo David C. , Orris Gregory J. 
Published: August 2015

AbstractWe explore an acoustic scattering cancellation shell for buoyant hollow cylinders submersed in a water background. A thin, low-shear, elastic coating is used to cancel the monopole scattering from an air-filled, neutrally buoyant steel shell for all frequencies where the wavelength is larger than the object diameter. By design, the uncoated shell also has an effective density close to the aqueous background, independently canceling its dipole scattering. Due to the significantly reduced monopole and dipole scattering, the compliant coating results in a hollow cylindrical inclusion that is simultaneously impedance and sound speed matched to the water background. We demonstrate the proposed cancellation method with a specific case, using an array of hollow steel cylinders coated with thin silicone rubber shells. These experimental results are matched to finite element modeling predictions, confirming the scattering reduction. Additional calculations explore the optimization of the silicone coating properties. Using this approach, it is found that scattering cross-sections can be reduced by 20 dB for all wavelengths up tok0a = 0.85.
Functional traits drive the contribution of solar radiation to leaf litter decomposition among multiple arid-zone species
Authors: Pan Xu , Song Yao-Bin , Liu Guo-Fang , Hu Yu-Kun , Ye Xue-Hua , Cornwell William K. , Prinzing Andreas , Dong Ming , Cornelissen Johannes H.C. 
Published: August 2015

AbstractIn arid zones, strong solar radiation has important consequences for ecosystem processes. To better understand carbon and nutrient dynamics, it is important to know the contribution of solar radiation to leaf litter decomposition of different arid-zone species. Here we investigated: (1) whether such contribution varies among plant species at given irradiance regime, (2) whether interspecific variation in such contribution correlates with interspecific variation in the decomposition rate under shade; and (3) whether this correlation can be explained by leaf traits. We conducted a factorial experiment to determine the effects of solar radiation and environmental moisture for the mass loss and the decomposition constantk-values of 13 species litters collected in Northern China. The contribution of solar radiation to leaf litter decomposition varied significantly among species. Solar radiation accelerated decomposition in particular in the species that already decompose quickly under shade. Functional traits, notably specific leaf area, might predict the interspecific variation in that contribution. Our results provide the first empirical evidence for how the effect of solar radiation on decomposition varies among multiple species. Thus, the effect of solar radiation on the carbon flux between biosphere and atmosphere may depend on the species composition of the vegetation.
Schizophrenia: a tale of two critical periods for prefrontal cortical development
Authors: Selemon L D , Zecevic N 
Published: August 2015

AbstractSchizophrenia is a disease of abnormal brain development. Considerable evidence now indicates that environmental factors have a causative role in schizophrenia. Elevated incidence of the disease has been linked to a wide range of disturbances in the prenatal environment and to social factors and drug intake during adolescence. Here we examine neurodevelopment of the prefrontal cortex in the first trimester of gestation and during adolescence to gain further insight into the neurodevelopmental processes that may be vulnerable in schizophrenia. Early embryonic development of the prefrontal cortex is characterized by cell proliferation, including renewal of progenitor cells, generation of early transient cell populations and neurogenesis of subcortical populations. Animal models show that curtailing early gestational cell proliferation produces schizophrenia-like pathology in the prefrontal cortex and mimics key behavioral and cognitive symptoms of the disease. At the other end of the spectrum, elimination of excitatory synapses is the fundamental process occurring during adolescent maturation in the prefrontal cortex. Adverse social situations that elevate stress increase dopamine stimulation of the mesocortical pathway and may lead to exaggerated synaptic pruning during adolescence. In a non-human primate model, dopamine hyperstimulation has been shown to decrease prefrontal pyramidal cell spine density and to be associated with profound cognitive dysfunction. Development of the prefrontal cortex in its earliest stage in gestation and in its final stage in adolescence represents two critical periods of vulnerability for schizophrenia in which cell proliferation and synaptic elimination, respectively, may be influenced by environmental factors.