bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparing US-GAAP and Iran-GAAP operating cash flows to predict future cash flows
Authors: Janjani Reza 
Published: June 2015

Purpose
– The main objective of this paper is to compare the ability of US-generally accepted accounting principles (GAAP) operating cash flows versus Iran-GAAP operating cash flows in predicting future cash flows.

Design/methodology/approach
– The sample comprises 240 firms (1,200 firm-years) during the period from 2004 to 2008 for which operating cash flows and other variables are available. Cross-sectional and panel data regression models are used in testing the hypotheses.

Findings
– This study finds that operating cash flows based on Iran-GAAP are no more effective in predicting future cash flows than those based on USA-GAAP, and the predictive ability of the model is improved by adding the earnings accrual components to the operating cash flows.

Originality/value
– The study suggests that the Iranian accounting standard setting committee recommends that the statement of cash flows be prepared based on the three-category model instead of the five-category model in an attempt to converge with the International Financial Reporting Standards. Consistent with Financial Accounting Standards Board and financial analyst recommendations, the results reveal that earnings are a better predictor than cash flows from operations.
Know the Lingo: how ILEAD Ohio influenced library collaboration and discovery for patrons
Authors: McIntosh Jessica Crossfield , Krumsee Kirstin , Zaveloff Julie E. , Zoladz Derek C. 
Published: June 2015

Purpose
– The purpose of this paper is to share the authors’ collective experiences of ILEAD, explore the mobile app (Know the Lingo) development process and inspire further use of the open access code. Libraries have changed over time, providing more and more access to information. Despite the goal of the library to serve as a provider of information resources, the authors’ classification systems, vocabulary and jargon can often alienate the majority of the users. The authors’ team, brought together by ILEAD Ohio, worked to determine a community need among the authors’ institutions, which led to the creation of Know the Lingo, a mobile application (app) that aids patrons with discovery.

Design/methodology/approach
– This paper will define and describe the application steps for ILEAD, the authors’ collaboration efforts and the finalization of the authors’ project.

Findings
– Throughout the process of ILEAD, the authors’ team discovered new ways to engage the communities, collaborate effectively and produce an innovative technological project.

Originality/value
– ILEAD is a new grant program that is operating through various states in the Midest. It is our hope that the program continues to grow, and this paper strives to support that mission. Leadership and community are strongly held values in the information science discipline, and ILEAD strives to provide that support to librarians across the country.
On eBooks in academic libraries: an article based on a presentation at the Library 2.014 Conference
Authors: Frederick Donna Ellen 
Published: June 2015

Purpose
– The purpose of this paper is to demonstrate and discuss some of the commonly held misconceptions about using and managing eBooks in academic research libraries and to outline what skills, abilities and knowledge are required of librarians and other library staff who work with eBooks. eBooks are an important presence in the vast majority of academic libraries. It is reasonable to expect that this presence will increase in the years to come. The value of eBooks to many students, faculty and researchers is undeniable and their availability has created new learning and teaching opportunities which were not possible with print-only library collection.

Design/methodology/approach
– eBooks bring multiple benefits to the academic environment.

Findings
– eBooks provide portable information resources for students and researchers doing fieldwork. eBooks have the potential for relieving pressure on space in some libraries. Some eBook platforms offer students new and enhanced ways for interacting with library materials, including accessibility features.

Originality/value
– The addition of eBooks to academic library collections addresses a growing preference among some patrons for information in electronic format.
Through the looking glass: thinking through the internet of things
Authors: Fernandez Peter 
Published: June 2015

Purpose
– This column aims to explore how the concept of the “Internet of Things” technology will impact everyday life, and examine its implications for libraries. The Internet serves as the foundation for a staggering array of connections between humans and computers all over the world. As a conceptual model, the “Internet of Things” (IOT) begs the question, what if the Internet expanded beyond humans and computers to include the other everyday objects that surround us?

Design/methodology/approach
– This column will explore how this technology might impact everyday life, and examine this technology’s implications for libraries.

Findings
– Companies of all kinds, including Intel, Microsoft, AT
&
T and DHL are all investing in the IOT, citing a variety of reports that estimate tremendous future growth. For example, a recent report by Business Insider predicts that by 2019, the IOT will be the largest device market in the world (overshadowing desktop computers and mobile devices combined) and create $1.7 trillion in new value, affecting business, homes, transportation, health care and government operations .

Originality/value
– Almost regardless of the success or failure of any given product, the concept of the IOT is a model that is affecting investors and businesses of all types, and in turn affecting technologies that are being developed today. By better understanding the IOT, librarians can therefore be better positioned to respond to developments as they emerge.
Bom m 9 from Bombyx mori is a novel protein related to asthma
Authors: Zuo Jianhong , Lei Mingsheng , Yang Rui , Liu Zhigang 
Published: June 2015

ABSTRACTThe silkworm (Bombyx mori) can cause severe IgE‐mediated allergic disease, however, the mechanism remains unclear. The aim of this study was to investigate the immunologic mechanism by which silkworms induce allergy. Whole silkworm pupa proteins were separated by SDS‐PAGE and 2‐D PAGE. Then, IgE‐binding proteins were detected by immunoblotting with sera of patients having an allergy to Bombyx mori. After tryptic digestion, the peptides of IgE‐binding proteins were analyzed by matrix‐assisted laser desorption ionization tandem time‐of‐flight mass spectrometry or tandem mass spectrometry. Database searches were used to identify allergens in silkworm pupa, after which Bom m 9 was to construct an asthma model. Thus, in the current study, a mouse asthma model was constructed with Bom m 9.
Clinical Validation of the Nursing Diagnosis Spiritual Distress in Cancer Patients Undergoing Chemotherapy
Authors: Caldeira Sílvia , Timmins Fiona , de Carvalho Emília Campos , Vieira Margarida 
Published: June 2015

ObjectiveValidate the nursing diagnosis spiritual distress in cancer patients.MethodsCross‐sectional approach using Richard Fehring's Clinical Diagnostic Validity Model.FindingsThe prevalence of diagnosis was 40.8% in a sample of 170 patients. A total of 16 defining characteristics were validated. Expresses suffering had the highest sensitivity value and lack of meaning in life had the highest specificity value.ConclusionsThe diagnosis was validated. Cancer patients in spiritual distress are in a state of suffering related to lack of meaning in life.Implications for PracticeSensitive diagnosis tools and language are required for nurses to make accurate judgments in situations of spiritual distress. Validation in different contexts would increase the clinical evidence of this diagnosis.
Associations between psychological variables and pain in experimental pain models. A systematic review
Authors: Hansen M. S. , Horjales‐Araujo E. , Dahl J. B. 
Published: June 2015

BackgroundThe association between pain and psychological characteristics has been widely debated. Thus, it remains unclear whether an individual's psychological profile influences a particular pain experience, or if previous pain experience contributes to a certain psychological profile. Translational studies performed in healthy volunteers may provide knowledge concerning psychological factors in healthy individuals as well as basic pain physiology. The aim of this review was to investigate whether psychological vulnerability or specific psychological variables in healthy volunteers are predictive of the level of pain following experimental pain models.MethodsA systematic search on the databases, PubMed, Embase, Cochcrane library, and Clinicaltrials.gov was performed during September 2014. All trials investigating the association between psychological variables and experimental pain in healthy volunteers were considered for inclusion.ResultsTwenty‐nine trials met the inclusion criteria, with a total of 2637 healthy volunteers. The included trials investigated a total of 45 different psychological tests and 27 different types of pain models. The retrieved trials did not present a sufficiently homogenous group to perform meta‐analysis. The collected results were diverse. A total of 16 trials suggested that psychological factors may predict the level of pain, seven studies found divergent results, and six studies found no significant association between psychological variables and experimental pain.ConclusionPsychological factors may have predictive value when investigating experimental pain. However, due to substantial heterogeneity and methodological shortcomings of the published literature, firm conclusions are not possible.
Ribosylation triggering Alzheimer's disease‐like Tau hyperphosphorylation via activation of CaMKII
Authors: Wei Yan , Han Chanshuai , Wang Yujing , Wu Beibei , Su Tao , Liu Ying , He Rongqiao 
Published: June 2015

SummaryType 2 diabetes mellitus (T2DM) is regarded as one of the serious risk factors for age‐related cognitive impairment; however, a causal link between these two diseases has so far not been established. It was recently discovered that, apart from high D‐glucose levels, T2DM patients also display abnormally high concentrations of uric D‐ribose. Here, we show for the first time that the administration of D‐ribose, the most active glycator among monosaccharides, produces high levels of advanced glycation end products (AGEs) and, importantly, triggers hyperphosphorylation of Tau in the brain of C57BL/6 mouse and neuroblastoma N2a cells. However, the administration of D‐glucose showed no significant changes in Tau phosphorylation under the same experimental conditions. Crucially, suppression of AGE formation using an AGEs inhibitor (aminoguanidine) effectively prevents hyperphosphorylation of Tau protein. Further study shows AGEs resulted from ribosylation activate calcium‐/calmodulin‐dependent protein kinase type II (CaMKII), a key kinase responsible for Tau hyperphosphorylation. These data suggest that there is indeed a mechanistic link between ribosylation and Tau hyperphosphorylation. Targeting ribosylation by inhibiting AGE formation may be a promising therapeutic strategy to prevent Alzheimer's disease‐like Tau hyperphosphorylation and diabetic encephalopathies.
Momentum in weekly returns: the role of intermediate‐horizon past performance
Authors: Chai Daniel , Limkriangkrai Manapon , Ji Philip Inyeob 
Published: June 2015

AbstractGutierrez and Kelly (2008) recently documented momentum in weekly returns. Using the Australian market as a setting, we find that stocks with high 1‐week returns exhibit a continuation in returns up to 1 year after a brief initial return reversal. However, after controlling for the intermediate‐horizon past performance, the continuation in returns after 1‐week returns disappears. These findings suggest that different past investment horizons contain separate information about price momentum and that intermediate‐term trends dominate short‐term trends in driving future returns. Overall, we show that understanding momentum over different horizons facilitates the design of more profitable trading strategies.
Comparison of psychotic bipolar disorder, schizoaffective disorder, and schizophrenia: an international, multisite study
Authors: Tondo L. , Vázquez G. H. , Baethge C. , Baronessa C. , Bolzani L. , Koukopoulos A. , Mazzarini L. , Murru A. , Pacchiarotti I. , Pinna M. , Salvatore P. , Sani G. , Selle V. , Spalletta G. , Girardi P. , Tohen M. , Vieta E. , Baldessarini R. J. 
Published: June 2015

ObjectiveNosological distinctions among schizoaffective disorder (SA), bipolar I disorder with psychotic features (BDp), and schizophrenia (SZ) remain unresolved.MethodWe compared 2269 subjects with psychotic features in DSM‐IV‐TR diagnoses (1435 BDp, 463 SZ, 371 SA) from 8 collaborating international sites, by 12 sociodemographic and clinical measures, all between diagnostic pairs.ResultsIn bivariate comparisons, SA was consistently intermediate between BDp and SZ for 11/12 features (except onset stressors), and SZ vs. BDp differed in all 12 factors. SA differed from both BDp and SZ in 9/12 factors: SA and BDp were similar in education and suicidal ideation or acts; SA and SZ were similar in education, onset stressors, and substance abuse. Meta‐analytic comparisons of diagnostic pairs for 10 categorical factors indicated similar differences of SA from both SZ and BDp. Multivariate modeling indicated significantly independent differences between BDp and SZ (8 factors), SA vs. SZ (5), and BDp vs. SA (3). Measurement variance was similar for all diagnoses.ConclusionSA was consistently intermediate between BDp and SZ. The three diagnostic groups ranked: BDp > SA > SZ related to lesser morbidity or disability. The findings are not consistent with a dyadic Kraepelinian categorization, although the considerable overlap among the three DSM‐IV diagnostic groups indicates uncertain boundaries if they represent distinct disorders.
Position paper of the EAACI: food allergy due to immunological cross‐reactions with common inhalant allergens
Authors: Werfel T. , Asero R. , Ballmer‐Weber B. K. , Beyer K. , Enrique E. , Knulst A. C. , Mari A. , Muraro A. , Ollert M. , Poulsen L. K. , Vieths S. , Worm M. , Hoffmann‐Sommergruber K. 
Published: June 2015

AbstractIn older children, adolescents, and adults, a substantial part of all IgE‐mediated food allergies is caused by cross‐reacting allergenic structures shared by inhalants and foods. IgE stimulated by a cross‐reactive inhalant allergen can result in diverse patterns of allergic reactions to various foods. Local, mild, or severe systemic reactions may occur already after the first consumption of a food containing a cross‐reactive allergen. In clinical practice, clinically relevant sensitizations are elucidated by skin prick testing or by the determination of specific IgE in vitro. Component‐resolved diagnosis may help to reach a diagnosis and may predict the risk of a systemic reaction. Allergy needs to be confirmed in cases of unclear history by oral challenge tests. The therapeutic potential of allergen immunotherapy with inhalant allergens in pollen‐related food allergy is not clear, and more placebo‐controlled studies are needed. As we are facing an increasing incidence of pollen allergies, a shift in sensitization patterns and changes in nutritional habits, and the occurrence of new, so far unknown allergies due to cross‐reactions are expected.
Urine exoglycosidases are potential markers of renal tubular injury in children with ureteropelvic junction obstruction
Authors: Taranta‐Janusz Katarzyna , Zalewska‐Szajda Beata , Chojnowska Sylwia , Wasilewska Anna 
Published: June 2015

AbstractAimHydronephrosis caused by ureteropelvic junction obstruction (UPJO) is an important problem in children and young adults. The aim of this pilot study was to determine the urine profiles of a number of lysosomal exoglycosidases to see whether they indicated tubular renal damage in children with UPJO.MethodsWe measured lysosomal exoglycosidases urine activities in 32 patients with UPJO, dividing them into three groups. The surgical group comprised 16 children with severe hydronephrosis who required surgery, the nonsurgical group comprised 16 patients with mild hydronephrosis, and the reference group comprised 42 healthy children. The following indicators were measured: N‑acetyl‑β‑hexosaminidase and its A and B isoenzymes, α‐fucosidase, β‐galactosidase, α‐mannosidase and β‐glucuronidase.ResultsThe urine activities of all exoglycosidases were significantly higher in children with UPJO than children in the reference group (p < 0.01). A strong positive correlation was also found between most of the urine exoglycosidases and the urine albumin/creatinine ratio (p < 0.01).ConclusionOur findings demonstrated that children with UPJO showed increased renal activities of assessed exoglycosidases, which correlated positively with the urine albumin/creatinine ratio. A larger multicentre study is required to confirm the clinical applications of these observations.
Mental health problems are rising more in Swedish adolescents than in other Nordic countries and the Netherlands
Authors: Bremberg Sven 
Published: June 2015

AbstractMental health problems increased in adolescents and young adults in Europe between 1950 and 1990, and the cause is largely unknown. Denmark, Finland, the Netherlands, Norway and Sweden form a relatively homogenous group of countries with favourable conditions for children. Our review examined the time trends for mental health problems in these countries between 1990 and 2010.ConclusionIn general, there were only small changes in mental health problems in the countries studied. However, we did note a marked rising trend in mental health problems among adolescents in Sweden, which also has more issues with school achievement and unemployment rates.
Ca2+‐activated K+ current is essential for maintaining excitability and gene transcription in early embryonic cardiomyocytes
Authors: Karppinen S. , Rapila R. , Naumenko N. , Tuomainen T. , Koivumäki J. T. , Hänninen S. L. , Korhonen T. , Tavi P. 
Published: June 2015

AbstractAimActivity of early embryonic cardiomyocytes relies on spontaneous Ca2+ oscillations that are induced by interplay between sarcoplasmic reticulum (SR) – Ca2+ release and ion currents of the plasma membrane. In a variety of cell types, Ca2+‐activated K+ current (IK(Ca)) serves as a link between Ca2+ signals and membrane voltage. This study aimed to determine the role of IK(Ca) in developing cardiomyocytes.MethodsIon currents and membrane voltage of embryonic (E9‐11) mouse cardiomyocytes were measured by patch clamp; [Ca2+]i signals by confocal microscopy. Transcription of specific genes was measured with RT‐qPCR and Ca2+‐dependent transcriptional activity using NFAT‐luciferase assay. Myocyte structure was assessed with antibody labelling and confocal microscopy.ResultsE9‐11 cardiomyocytes express small conductance (SK) channel subunits SK2 and SK3 and have a functional apamin‐sensitive K+ current, which is also sensitive to changes in cytosolic [Ca2+]i. In spontaneously active cardiomyocytes, inhibition of IK(Ca) changed action and resting potentials, reduced SR Ca2+ load and suppressed the amplitude and the frequency of spontaneously evoked Ca2+ oscillations. Apamin caused dose‐dependent suppression of NFAT‐luciferase reporter activity, induced downregulation of a pattern of genes vital for cardiomyocyte development and triggered changes in the myocyte morphology.ConclusionThe results show that apamin‐sensitive IK(Ca) is required for maintaining excitability and activity of the developing cardiomyocytes as well as having a fundamental role in promoting Ca2+‐ dependent gene expression.
Faecal microbiota transplantation plus selected use of vancomycin for severe‐complicated Clostridium difficile infection: description of a protocol with high success rate
Authors: Fischer M. , Sipe B. W. , Rogers N. A. , Cook G. K. , Robb B. W. , Vuppalanchi R. , Rex D. K. 
Published: June 2015

SummaryBackgroundSevere and severe/complicated Clostridium difficile infection (CDI) can result in ICU admission, sepsis, toxic megacolon and death. In this setting, colectomy is the standard of care but it is associated with a 50% mortality.AimTo evaluate safety and efficacy of a sequential faecal microbiota transplantation (FMT) and antibiotic protocol in severe and severe/complicated CDI patients who are at high risk for colectomy.MethodsAll patients with severe and severe/complicated CDI refractory to oral vancomycin ± rectal vancomycin and intravenous metronidazole therapy were offered FMT. Treatment consisted of sequential FMTs via colonoscopy with the need for repeat FMT and continued vancomycin guided by clinical response and pseudomembranes at colonoscopy.ResultsA total of 29 patients underwent FMT between July 2013 and August 2014. The overall treatment response of endoscopic sequential FMT was 93% (27/29), with 100% (10/10) for severe CDI and 89% (17/19) for severe/complicated CDI. A single FMT was performed in 62%, two FMTs were performed in 31% and three FMTs in 7% of patients. The use of non‐CDI antibiotics predicted repeat FMT (odds ratio = 17.5). The 30‐day all‐cause mortality after FMT was 7%, and the cumulative 3‐month survival was 76%. Of the two patients who died within 30 days, one underwent colectomy and succumbed to sepsis; the other died from septic shock related to CDI.ConclusionThe success of a treatment protocol for severe and severe/complicated involving faecal microbiota transplantation and continued vancomycin in selected patients was high, and it warrants further evaluation.