bluuebunny/crossref_metadata_2025_split huggingface dataset:
The role of gender in shaping the destination service quality and its consequences
Authors: Tosun Cevat , Dedeoglu Bekir Bora , Usakli Ahmet 
Published: August 2024

AbstractThis study investigates the moderating role of gender on the relationships between destination service quality, affective image, and revisit intention. A convenience sample of 1768 visitors to Macau was surveyed and 1424 useable questionnaires were analyzed. The destination service quality was measured using seven dimensions: (1) accommodation, (2) local transport, (3) cleanliness, (4) hospitality, (5) activities, (6) language communication, and (7) airport services. The data was analyzed using covariance‐based structural equation modeling. The results indicate that “accommodation, local transport, hospitality, and airport services” have positive effects on affective image, and affective image, in turn, positively influences revisit intention. The study also reveals three significant findings regarding the moderating role of gender. While the positive impact of hospitality on affective image were found to be stronger for female visitors, the positive impacts of local transport and airport services on affective image were found to be stronger for male visitors.
Color and naturalness: How color saturation shapes tourists' perception and purchase intention
Authors: Zhang Ke , Hou Yuansi , Li Gang 
Published: August 2024

AbstractMany tourist destinations and hospitality companies are using the idea of “naturalness” to attract consumers in the post‐pandemic era. The current research explores the impact of color, a fundamental element in tourism marketing materials, on shaping tourists' perceptions of naturalness and subsequent purchase intention. Through three experimental studies, our research reveals a lay belief that associates color saturation with naturalness perception. While prior research has indicated that highly saturated colors can positively impact consumers, our findings suggest that this effect may not always hold. Specifically, low color saturation in tourism marketing materials increased tourists' perceptions of naturalness and purchase intentions. These findings contribute to the theoretical development of color psychology and support the development of sustainable tourism and hospitality practices that prioritize managing natural resources.
Safety of Percutaneous Dilatational Tracheostomy in Critically Ill Adults With Obesity: A Retrospective Cohort Study
Authors: Siafa Lyna , El‐Malt Farida , Roy Catherine F. , Kost Karen M. 
Published: August 2024

ObjectiveThis study aimed to assess the safety and efficacy of endoscopic percutaneous dilatational tracheostomy (PDT) in obese and nonobese critically ill adults.MethodsA retrospective study of all cases of PDT performed at two academic health centers between 2016 and 2023 was conducted. Primary outcomes included peri‐ and postoperative complications stratified by both timing and severity. body mass index (BMI) data were stratified according to the World Health Organization classification (class I obesity defined as BMI ≥ 30, class II obesity ≥35 and <40, class 3 obesity ≥40).ResultsTotally 336 patients underwent a PDT, 279 of whom had available BMI data: 193 (69.2%) patients had a normal BMI, 56 (20.1%) had class I obesity, 15 (5.4%) class II obesity, and 15 (5.4%) class III obesity. The overall complication rates for the class I, II, and III obesity were 8.9%, 13.3%, and 13.3%, respectively. All procedures were successfully completed at the bedside (no conversions to an open approach), and there was no procedure‐related mortality. The only accidental decannulation event was in a patient with class III obesity. There was no difference in overall complication rates between patients without obesity and patients with obesity (7.3% vs. 10.5%, respectively, p = 0.370).ConclusionThis study significantly expands the current literature and represents one of the largest studies to date reporting on PDT in patients with obesity.Level of Evidence3 Laryngoscope, 134:5015–5020, 2024
Optics‐Enabled Highly Scalable Inverter for Multi‐Valued Logic
Authors: Kaushal Saket , Aadhi A. , Roberge Anthony , Morandotti Roberto , Kashyap Raman , Azaña José 
Published: August 2024

AbstractThe rapid advancements in machine learning have exacerbated the interconnect bottleneck inherent in binary logic‐based computing architectures. An interesting approach to tackle this problem involves increasing the information density per interconnect, i.e., by switching from a two‐valued to a multi‐valued logic (MVL) architecture. However, current MVL implementations offer limited overall performance and face challenges in scaling to process data signals with radix (number of logic levels) even just above 3. In this work, a novel concept is introduced for implementation of a highly scalable and fully passive inverter based on the frequency‐domain phase‐only linear manipulation of the input MVL data signal, which is encoded in the amplitude variations of an electromagnetic wave along the time axis. As a key advantage, this solution is entirely independent of the input radix. The proposed design is implemented using an optical fibre Bragg grating device. Inversion of quaternary signals is experimentally demonstrated, as well as binary and ternary signals, at a remarkable operation speed of 32 GBaud, with an estimated energy consumption of 24 fJ/bit. The proposed method is universal and can be applied to any system that supports transmission and detection of coherent waves, such as microwave, plasmonic, mechanical, or quantum.
Harnessing the Photoperformance of N‐Methyl‐Quinolinone for Gated Photo‐Driven Cyclability and Reversible Photoligation
Authors: Streicher Moritz , Stamp Claas‐Hendrik , Kluth Marco Dante , Ripp Alexander , Calvino Céline 
Published: August 2024

Abstract[2π + 2π]‐photocycloadditions and their ability to trigger controlled and reversible photoligation through disparate wavelengths provide an attractive platform to unlock advanced functionalities in soft materials. Yet, among the limited amount of functional motifs enabling reversible photoreactions, cyclability is often overlooked due to poor reaction yield and orthogonality. In this study, the advantageous photocharacteristics of the previously underexplored N‐methyl‐quinolinone photoresponsive motif are leveraged to create a covalent gated system, enabling controlled formation and cleavage of covalent bonds on demand. A systematic evaluation of individual cycloadditions and reversions on the molecular scale, including reaction rates, conversions, and photoproducts, allows identification of the required conditions for generating controlled photoreactions with a remarkable degree of cyclability; while, maintaining high reaction yields. Ultimately, these controlled and cyclable reactions are translated to a macromolecular scale, showcasing a comparable performance in initiating reversible photoligation, as observed at the molecular level. In addition, it is also shown that this progressive methodology can be leveraged to gain a comprehensive understanding of cyclability and clarify the factors contributing to its decreasing yield. Overall, unlocking the potential of quinolinone derivatives through this step‐by‐step approach lays the foundation for the development of highly controlled and responsive polymer materials with unprecedented potential.
Transfusional hemosiderosis in childhood cancer patients and survivors
Authors: Baskin‐Miller Jacquelyn , Carson Susan , Jaffray Julie , Fletcher Craig , Singer Jessie , Freyer David R. , Wood John , Coates Thomas D. , Denton Christopher C. 
Published: August 2024

AbstractBackgroundChildren treated for cancer are at risk for adverse effects of iron due to transfusions administered during prolonged marrow suppression, which may increase exposure to toxic forms of iron, extrahepatic iron accumulation, and long‐term organ damage.ObjectiveThis study aimed to characterize the severity and organ distribution of clinically significant, multisystem iron overload (IO) in an at‐risk cohort of pediatric cancer patients.MethodsThis was a retrospective, cross‐sectional study of childhood cancer patients who underwent a magnetic resonance imaging (MRI) due to clinical concern for IO. Data regarding cancer type and treatment, transfusion history, MRI and laboratory results, and treatment for IO were collected. Severity of IO was analyzed by non‐parametric tests with respect to clinical characteristics.ResultsOf the 103 patients, 98% of whom had a Cancer Intensity Treatment Rating (ITR‐3) of 3 or higher, 53% (54/102) had moderate or greater hepatic siderosis, 80% (77/96) had pancreatic siderosis, 4% (3/80) had cardiac siderosis, and 45% (13/29) had pituitary siderosis and/or volume loss. Pancreatic iron was associated with both cardiac (p = .0043) and pituitary iron (p = .0101). In the 73 off‐therapy patients, ferritin levels were lower (p = .0008) with higher correlation with liver iron concentration (LIC) (p = .0016) than on‐therapy patients. Fifty‐eight subjects were treated for IO.ConclusionIn this heavily treated cohort of pediatric cancer patients, more than 80% had extrahepatic iron loading, which occurs with significant exposure to toxic forms of iron related to decreased marrow activity in setting of transfusions. Further studies should examine the effects of exposure to reactive iron on long‐term outcomes and potential strategies for management.
GPCR Signaling: A Study of the Interplay Between Structure, Energy, and Function
Authors: Chalopin Yann 
Published: August 2024

ABSTRACTG protein‐coupled receptors (GPCRs) exemplify sophisticated allosteric communication, transducing extracellular signals through ligand‐induced structural rearrangements that resonate through the molecular scaffold. Despite extensive study, the biophysical underpinnings of how conformational changes spread remain unclear. This work employs a novel physics‐based framework to characterize the role of energy dissipation in directing intramolecular signaling pathways. By modeling each residue as a network of coupled oscillators, we generate a localization landscape depicting the vibrational energy distribution throughout the protein scaffold. Quantifying directional energy flux between residues reveals distinct pathways for energy and information transfer, illuminating sequences of allosteric communication. Our analysis of CB1 and CCR5 crystal structures unveils an anisotropic pattern of energy dissipation aligning with key functional dynamics, such as activation‐related conformational changes. These anisotropic patterns of vibrational energy flow constitute pre‐configured channels for allosteric signaling. Elucidating the relationship between structural topology and energy dissipation patterns provides key insights into the thermodynamic drivers of conformational signaling. This methodology significantly advances our mechanistic understanding of allostery in GPCRs and presents a broadly applicable approach for rationally dissecting allosteric communication pathways, with potential implications for structure‐based drug design targeting these critical receptors.
Establishing a limited‐area model based on a global model: A consistency study
Authors: Zhang Yi , Liu Zhuang , Wang Yiming , Chen Siyuan 
Published: August 2024

AbstractA limited‐area model (LAM) is established based on a global model (Global–Regional Integrated Forecast System; GRIST). GRIST–LAM inherits all the technical features of its global counterpart, enabling independent regional weather and climate modeling. The key advancement involves extending the original dynamical core to integrate it under the lateral boundary conditions (LBCs). As an initial development and evaluation study, this paper focuses on the consistency issue between the LAM and the global model. Three perfect‐model tests, using global solutions as LBCs and background truths, were performed to evaluate the LAM behaviors. In the pure dynamical core test, the LBC errors do not compromise the solutions within the interior domain. However, certain configurations can lead to more discontinuous solutions at the domain boundary. The solution error for a specified region decreases as the domain size increases when all other factors are equal. A small error pulse is generated during the initial stage of integration due to the presence of artificial transient waves induced by the LBCs. The model generates fine‐scale details and smaller errors based on coarser‐resolution LBCs. The consistency between LAM and LBC also influences the errors. The climate simulations demonstrate that both hydrostatic and non‐hydrostatic LAMs can reach statistical equilibrium. Regional model climates in the interior domain have higher quality but are sensitive to domain size and LBC configuration. Using a variable LBC coefficient is helpful to alleviate the artificial precipitation at the boundary. In the kilometer‐scale test, the global variable‐resolution model and its LAM counterpart show comparable results. Their performance is competitive with that of a uniform‐resolution global storm‐resolving simulation. Global variable‐resolution and LAM generate higher magnitudes in the tail part of the kinetic energy spectra due to higher local resolution and produce a consistent time evolution of precipitation. The broad implication of this study is also discussed.
High‐Energy Polynitrogen N10 Stabilized on Multi‐Walled Carbon Nanotubes
Authors: Hou Tianyang , Guo Ke , Zhu Jiawei , Xu Ze , Zhang Xiaopeng , Zhang Kan , Lu Ming , Tao Li , Xu Yuangang 
Published: August 2024

AbstractThe synthesis of stable polynitrogen compounds with high‐energy density has long been a major challenge. The cyclo‐pentazolate anion (cyclo‐N5−) is successfully converted into aromatic and structurally symmetric bipentazole (N10) via electrochemical synthesis using highly conductive multi‐walled carbon nanotubes (MWCNTs) as the substrate and sodium pentazolate hydrate ([Na(H2O)(N5)]·2H2O) as the raw material. Attenuated total refraction Fourier transform infrared spectroscopy, Raman spectroscopy, X‐ray diffraction, X‐ray photoelectron spectroscopy, transmission electron microscopy, and density functional theory calculations confirmed the structure and homogeneous distribution of N10 in the sidewalls of the MWCNTs (named MWCNT‐N10‐n m). The MWCNT‐N10‐2.0 m is further used as a catalyst for electrochemical oxygen reduction to synthesize hydrogen peroxide from oxygen with a two‐electron selectivity of up to 95%.
Synthesis of Carboxyl‐Functionalized COFs with Alternate Stable β‐Ketoenamine and Benzimidazole Linkages: Unraveling Exceptional Solvent Effects for Efficient Uranium Separation
Authors: Liu Weijian , Li Xiaofeng , He Pan , Li Bo , Liu Ning , Li Yang , Ma Lijian 
Published: August 2024

AbstractThe prevalent π–π interactions in 2D covalent organic frameworks (COFs) impart a certain flexibility to the structures, making the stacking of COF layers susceptible to external stimuli and introducing some structural disorder. Recent research indicates that the flexibility between COF layers and the associated disorder significantly influence their selective adsorption performance toward gas molecules. However, the adsorption process in a solution environment is more complex compared to gas‐phase adsorption, involving interactions between adsorbents and adsorbates, as well as the solvation effects of flexible 2D COFs. Therefore, the inherent flexibility and disorder in 2D COFs under solution conditions and their impact on the adsorption performance of metal ions have not been observed yet. Herein, the synthesis of a novel carboxyl‐functionalized COF featuring stable β‐ketoenamine and benzimidazole linkages, named DMTP‐COOH, is presented. DMTP‐COOH exhibits excellent selective adsorption capability for uranium, with significantly different adsorption capacities observed after treatment with different solvents. This notable difference in adsorption capacity is observed under varying pH, concentration, time, and even in the presence of multiple competing ions. This work represents the first observation of the significant impact of solvent soaking treatment on the selective adsorption performance of COFs for uranium under liquid conditions.
Photo‐Activated Oxidative Stress Amplifier: A Strategy for Targeting Glutathione Metabolism and Enhancing ROS‐Mediated Therapy in Triple‐Negative Breast Cancer Treatment
Authors: Zhao Li , Tong Yao , Yin Jiawei , Li Hui , Du Lutao , Li Juan , Jiang Yanyan 
Published: August 2024

AbstractAmplifying oxidative stress within tumor cells can effectively inhibit the growth and metastasis of triple‐negative breast cancer (TNBC). Therefore, the development of innovative nanomedicines that can effectively disrupt the redox balance represents a promising yet challenging therapeutic strategy for TNBC. In this study, an oxidative stress amplifier, denoted as PBCH, comprising PdAg mesoporous nanozyme and a CaP mineralized layer, loaded with GSH inhibitor L‐buthionine sulfoximine (BSO), and further surface‐modified with hyaluronic acid that can target CD44, is introduced. In the acidic tumor microenvironment, Ca2+ is initially released, thereby leading to mitochondrial dysfunction and eventually triggering apoptosis. Additionally, BSO suppresses the synthesis of intracellular reduced GSH and further amplifies the level of oxidative stress in cancer cells. Furthermore, PdAg nanozyme can be activated by near‐infrared light to induce photothermal and photodynamic effects, causing a burst of ROS and simultaneously promoting cell apoptosis via provoking immunogenic cell death. The high‐performance therapeutic effects of PBCH, based on the synergistic effect of aforementioned multiple oxidative damage and photothermal ablation, are validated in TNBC cells and animal models, declaring its potential as a safe and effective anti‐tumor agent. The proposed approach offers new perspectives for precise and efficient treatment of TNBC.
In Situ Synthesis of High‐Entropy (Oxy)Hydroxides Via Electrochemical Reconfiguration As Catalysts For Efficient Water Oxidation
Authors: Shen Weilin , Du Yan , Liu Huibin , Tsang Chi‐Wing , Chen Xiao , Liang Changhai 
Published: August 2024

AbstractSurface reconstruction plays a pivotal role in enhancing the activity of the oxygen evolution reaction (OER), particularly in terms of the structural transformation from metal oxides to (oxy)hydroxides. Herein, a novel (oxy)hydroxide (FeCoNiCuMoOOH) with high entropy is developed by the electrochemical reconstitution of corresponding oxide (FeCoNiCuMoOx). Significantly, the FeCoNiCuMoOOH exhibits much higher OER electrocatalytic activity and durability with an overpotential as low as 201 mV at a current density of 10 mA cm−2, and with a Tafel slope of 39.4 mV dec−1. The FeCoNiCuMoOOH/NF presents high stability when testing under a constant current at 100 mA cm−2 within 1000 h. The surface reconstruction is a process of dissolution‐reprecipitation of Cu and Mo species and co‐hydroxylation of five metal species, which ultimately leads to the formation of FeCoNiCuMoOOH from FeCoNiCuMoOx. This study holds great significance in the realm of designing high‐entropy (oxy)hydroxides catalysts with exceptional activity and stability for OER.
Pd Nanoparticle Size‐Dependent H* Coverage for Cu‐Catalyzed Nitrate Electro‐Reduction to Ammonia in Neutral Electrolyte
Authors: Zhu Hongbo , Wang Jiacheng Jayden , Xu Zian , Tan Yongwen , Wang Jiacheng 
Published: August 2024

AbstractElectrochemical conversion of nitrate (NO3−) to ammonia (NH3) is an effective approach to reduce nitrate pollutants in the environment and also a promising low‐temperature, low‐pressure method for ammonia synthesis. However, adequate H* intermediates are highly expected for NO3− hydrogenation, while suppressing competitive hydrogen evolution. Herein, the effect of H* coverage on the NO3RR for ammonia synthesis by Cu electrocatalysts is investigated. The H* coverage can be adjusted by changing Pd nanoparticle sizes. The optimized Pd@Cu with an average Pd size of 2.88 nm shows the best activity for NO3RR, achieving a maximum Faradaic efficiency of 97% (at −0.8 V vs RHE) and an NH3 yield of 21 mg h−1 cm−2, from an industrial wastewater level of 500 ppm NO3–. In situ electrochemical experiments indicate that Pd particles with 2.88 nm can promote NO3− hydrogenation to NH3 via well‐modulated coverage of adsorbed H* species. Coupling the anodic glycerol oxidation reaction, ammonium and formate are successfully obtained as value‐added products in a membrane electrode assembly electrolyzer. This work provides a feasible strategy for obtaining size‐dependent H* intermediates for hydrogenation.
BELIEVE in collaboration: Effective evaluation partnerships for National Professional Development projects
Authors: Moore Raeal , Gimbert Belinda G. , Becce Melissa 
Published: August 2024

AbstractQuality partnerships are imperative for successful project implementation. The partnership between project personnel and independent evaluators is often overlooked. In effective partnerships, both the evaluators and the education project management team collectively ensure that educational initiatives are well‐planned, executed, and assessed. This collaborative approach fosters a culture of continuous improvement and accountability, ultimately leading to better educational outcomes for English learner students, educators, and the community. This conceptual article highlights eight elements of an effective project management and evaluator partnership: (1) clear communication and collaboration, (2) goal alignment, (3) early planning for evaluation, (4) multi‐purpose evaluation activities, (5) shared responsibility, (6) feedback loops, (7) transparency, and (8) evaluation capacity building. The authors present these elements through the design, deployment, analysis, and use of the Better English Learners Instruction and Education in Varied Environments (BELIEVE) classroom observation tool. The tool was collaboratively created and deployed across two National Professional Development grants in response to the COVID‐19 pandemic, addressing the need for a tool that could be used in varying learning modes and capture how effectively classroom teachers were teaching academic content and literacy to English learners in elementary and middle schools. The article illustrates how this tool has been used by program personnel to inform the teacher–coach relationship and educate teachers and administrators about best practices, and by the evaluation team to assess the progress of teachers' use of research‐based practices to teach English learners.
Corrosion protection of mild steel in water‐in‐diesel emulsion using Ocimum gratissimum extract
Authors: Onuoha Chiamaka Prisca , Etim Ini‐ibehe Nabuk , Oguzie Emeka Emmanuel 
Published: August 2024

AbstractWater‐in‐diesel emulsions (WiDEs) have been developed in recent times to assuage costs as well as to minimize lethal emissions from diesel combustion, without engine modification. This study investigated the stability behavior of WiDE and the corrosion inhibition efficacy of the ethanol extract of Ocimum gratissimum (O. gratissimum) toward mild steel. The corrosion susceptibility of mild steel coupons immersed in the different WiDE formulations was monitored using gravimetric and surface probe techniques. The anti‐corrosion effect of O. gratissimum was also assessed. The findings revealed that out of WiDE with three different water content, WiDE with 10% water content had optimal stability and emulsion stability declined with a rise in water content. The mild steel's corrosion rate decreased with a rise in exposure duration. The ethanol extract of O. gratissimum has a substantial impact on the corrosion behavior of mild steel in WiDE, reaching an inhibition efficiency of 91.58%. Also, the apparent surface roughness and roughness data (Sq, Sa,) of mild steel immersed in WiDE10 are higher than the WiDE10 inhibited with O. gratissimum extract, which shows that corrosion was reduced upon the addition of O. gratissimum extract. The FTIR spectra proved the adsorption of the extract constituents on the mild steel surface in WiDE.