The Subjective Sexual Effects of Intravenous Methamphetamine Use in Women
Authors: Kennedy Aliyah , Qayyum Maira , Goeders Nicholas , Zoorob Dani 
Published: July 2024

Purpose: This study aimed to identify the sexual effects of methamphetamine on female users and determine the factors that encourage continued use of this substance.  Methods: This structured interview study was approved by the Institutional Review Board at Louisiana State University Health Shreveport. The research participants were female volunteers that reported either currently or previously using methamphetamine. One study team member conducted all the interviews similarly to reduce variability between interviews. This individual was a doctorate-level addiction specialist to ensure the integrity and value of the data collection. All interviews were conducted in private offices at the Council on Alcoholism and Drug Abuse of Northwest Louisiana (CADA) facility in Bossier City, LA, between January 25, 2013, and October 7, 2014. Each volunteer provided informed consent to participate in the study. The specialist asked study subjects open-ended questions, and each conversation lasted approximately one hour. The specialist started each interview with an inquiry regarding the participant’s experiences with methamphetamine. The interviewer would particularly ask about the activities in which that participant would become involved immediately after using methamphetamine. The research subject was given time to discuss any sexual effects of using this stimulant without any prompting by the interviewer. If the study participant did not broach this topic during the interview, the specialist would ask them, “How does methamphetamine make you feel?” This “trigger” question was developed with the primary objective of the study in mind, which was identifying the sexual effects of methamphetamine use on females. Descriptive statistical analysis was performed on the data collected from the interviews.  Results: Fifty-six interviews were conducted over 1.5 years. The mean age of the research subjects was determined to be 34.5 (± 10.2; range: 18 to 56). The entire study population was comprised of white females. Fifty (90%) of the study subjects utilized methamphetamine through the intravenous route. Most of these intravenous users (96%) had smoked, snorted, or ingested the substance prior to injecting the substance. Forty-four (88%) of the research participants who engaged in intravenous methamphetamine use reported feeling sexual arousal and an immediate sensation of pleasure indistinguishable from that attributed to orgasm when they injected the substance. The methamphetamine had to be of “sufficient amount and of better quality,” according to these subjects, to elicit this effect. None of the individuals interviewed reported a feeling similar to orgasm when they smoked or snorted methamphetamine. Many subjects stated that they engaged in intravenous methamphetamine use as frequently as every two hours to keep experiencing the sexual response, even if they still felt intoxicated. Twelve (21%) of the subjects reported being directed towards intravenous methamphetamine use by other females describing the sexual effects. Twenty-three (47%) of the participants recounted immediate “vapors,” which were described as “cough” or “taste” of the drug. None of the subjects said they had previously shared the sexual component of their experience with methamphetamine use with medical providers. All participants recounted disinhibition regarding sex but not social interactions. They also declared indifference to the consequences of high-risk sexual behavior and unsafe use of needles. Four subjects admitted avoiding hospital settings because they feared their methamphetamine use would be discovered. Conclusion: Female study participants who currently use or previously used methamphetamine reported a sexual response to intravenous use of the substance. Females who use methamphetamine were drawn toward intravenous use for the sexual experience, and those who use intravenous methamphetamine increase the frequency of use to reexperience the sexual response. These findings indicate that the sexual effects attributed to intravenous methamphetamine may contribute to its ongoing and recurrent use.