bluuebunny/crossref_metadata_2025_split huggingface dataset:
Consensus statement addressing controversies and guidelines on pediatric urolithiasis
Authors: Güven S. , Tokas T. , Tozsin A. , Haid B. , Lendvay T. S. , Silay S. , Mohan V. C. , Cansino J. R. , Saulat S. , Straub M. , Tur A. Bujons , Akgül B. , Samotyjek J. , Lusuardi L. , Ferretti S. , Cavdar O. F. , Ortner G. , Sultan S. , Choong S. , Micali S. , Saltirov I. , Sezer A. , Netsch C. , de Lorenzis E. , Cakir O. O. , Zeng G. , Gozen A. S. , Bianchi G. , Jurkiewicz B. , Knoll T. , Rassweiler J. , Ahmed K. , Sarica K. 
Published: August 2024

Abstract
Purpose
We aimed to investigate controversial pediatric urolithiasis issues systematically, integrating expert consensus and comprehensive guidelines reviews.

Methods
Two semi-structured online focus group meetings were conducted to discuss the study’s need and content, review current literature, and prepare the initial survey. Data were collected through surveys and focus group discussions. Existing guidelines were reviewed, and a second survey was conducted using the Delphi method to validate findings and facilitate consensus. The primary outcome measures investigated controversial issues, integrating expert consensus and guideline reviews.

Results
Experts from 15 countries participated, including 20 with 16+ years of experience, 2 with 11–15 years, and 4 with 6–10 years. The initial survey identified nine main themes, emphasizing the need for standardized diagnostic and treatment protocols and tailored treatments. Inter-rater reliability was high, with controversies in treatment approaches (score 4.6, 92% agreement), follow-up protocols (score 4.8, 100% agreement), and diagnostic criteria (score 4.6, 92% agreement). The second survey underscored the critical need for consensus on identification, diagnostic criteria (score 4.6, 92% agreement), and standardized follow-up protocols (score 4.8, 100% agreement).

Conclusion
The importance of personalized treatment in pediatric urolithiasis is clear. Prioritizing low-radiation diagnostic tools, effectively managing residual stone fragments, and standardized follow-up protocols are crucial for improving patient outcomes. Integrating new technologies while ensuring safety and reliability is also essential. Harmonizing guidelines across regions can provide consistent and effective management. Future efforts should focus on collaborative research, specialized training, and the integration of new technologies in treatment protocols.
Acetabular posterior column screws via an anterior approach
Authors: Krappinger Dietmar , Gänsslen Axel , Wilde Lukas , Lindtner Richard A. 
Published: August 2024

AbstractScrew fixation of acetabular column fractures is a well-established alternative option to plate fixation providing comparable biomechanical strength and requiring less surgical exposure. For displaced acetabular fractures involving both columns open reduction and plate fixation of one column in combination with a column-crossing screw fixation of the opposite column via a single approach is a viable treatment option. Preoperative planning of posterior column screws (PCS) via an anterior approach is mandatory to assess the eligibility of the fracture for this technique and to plan the entry point and the screw trajectory. The intraoperative application requires fluoroscopic guidance using several views. A single view showing an extraarticular screw position is adequate to rule out hip joint penetration. The fluoroscopic assessment of cortical perforation of the posterior column requires several oblique views such as lateral oblique views, obturator oblique views and axial views of the posterior column or alternatively intraoperative CT scans. The application of PCS via an anterior approach is a technically demanding procedure, that allows for a relevant reduction of approach-related morbidity, surgical time and blood loss by using a single approach.
The analysis of tear meniscus parameters during daily soft contact lens wear using optical coherence tomography
Authors: Dogan Levent , Arslan Gurcan Dogukan 
Published: August 2024

Abstract

Purpose
To evaluate tear meniscus parameters in soft contact lens wearers (SCL) using optical coherence tomography (OCT) and ImageJ software.

Methods
This prospective study included 50 soft contact lens wearers (group 1: 25 symptomatic SCL wearers (SCLW), group 2: 25 asymptomatic SCL wearers (ASCW)) and 25 healthy non-CL wearers (group 3 (NCLW)). SCLs were fitted on each eye of CL wearers, and the lower tear meniscus was imaged using OCT before CL insertion, immediately afterward, and reimaged 2, 5 and 10 h after insertion. Tear meniscus parameters, including tear meniscus height (TMH), depth (TMD), turbidity, and percentage area occupied by particles (PAOP) were measured in all groups.

Results
Turbidity and PAOP measurements at baseline in SCLW were significantly higher than in other groups (p < 0.05). There was no significant difference between TMH, TMD, turbidity, and PAOP parameters calculated at baseline visit and two hours after SCL insertion in all groups (p > 0.05 for 2 comparisons). The symptomatic SCL users had a significant decrease in TMH and TMD in the fifth hour. The turbidity and PAOP measurements of SCLW and ASCW at the fifth and tenth hours were significantly higher than those of NCLW (p < 0.05).

Conclusion
TMD and height TMH decrease throughout the day in all participants; however, a significant decrease in these parameters was observed only in symptomatic SCL users at the fifth hour, at the earliest. As the duration of CL wear increases, turbidity and PAOP even in asymptomatic SCL wearers become significantly higher than those in healthy non-CL wearers.

Key Messages

What Is Known

• Contact lens wear is associated with an increased risk of dry eye.
• Tear volume decreases gradually during contact lens wear.

What Is New

• Tear meniscus turbidity and particle area occupied by particles (PAOP) were higher in symptomatic contact lens wearers and they increase gradually during contact lens wear.
• Tear meniscus turbidity and PAOP may be measures of how well the tear film and meniscus are functioning in contact lens wearers.
Immediate effect of local vibration on motor unit firing behavior and muscle strength in healthy young adult males
Authors: Nishikawa Yuichi , Holobar Aleš , Watanabe Kohei , Komatsuzaki Toshihiko , Chihara Takanori , Sakamoto Jiro , Kawagoe Takashi , Nagayasu Hidetaka , Mori Kyoko , Kawano Kenji , Maeda Noriaki , Tanaka Shinobu , Hyngstrom Allison S. 
Published: August 2024

Abstract
Purpose
The aim of this study was to examine the effect of vibration on motor unit (MU) firing behavior and physical performance of antagonist muscles in healthy young adult males.

Methods
Fourteen males (age = 24.3 ± 3.6 years) were included in this study. There were two conditions, one in which participants received 80 Hz vibration in the distal tendon of the hamstring for 30 s and the control condition (no vibration). High-density surface electromyography (HD-SEMG) signals and maximal voluntary contraction (MVC) of knee extensor muscles were evaluated before and after the respective conditions and recorded from the vastus lateralis muscle during submaximal ramp-up and sustained contractions at 30% MVC. Convolution blind source separation was used to decompose the HD-SEMG signals into individual MU firing behaviors.

Results
In total, 739 MUs were detected (control; 360 MUs and vibration; 379 MUs), and a total of 312 matched MUs were identified across both submaximal contraction conditions (control: 150 MUs; vibration: 162 MUs). Vibration significantly increased the discharge rate (p = 0.047) and decreased the recruitment threshold before and after intervention (p = 0.001) but not in the control condition. Furthermore, the recruitment threshold is a factor that influences discharge rate. Significant correlations were observed between the recruitment threshold and both the ∆ discharge rate and the ∆ recruitment threshold under the vibration condition (p < 0.001).

Conclusion
Vibration increased in the discharge rate and decreased the recruitment threshold of the antagonist muscle. These findings suggested that vibration contributes to immediate changes in the neural control of antagonist muscles.
The Impact of Different MEFV Genotypes on Clinical Phenotype of Patients with Familial Mediterranean Fever: Special Emphasis on Joint Involvement
Authors: Aslan Esma , Akay Nergis , Gul Umit , Konte Elif Kilic , Gunalp Aybuke , Haslak Fatih , Adrovic Amra , Barut Kenan , Yildiz Mehmet , Sahin Sezgin , Kasapcopur Ozgur 
Published: August 2024

AbstractFamilial Mediterranean Fever (FMF) is the most common monogenic autoinflammatory disease worldwide. In this retrospective cohort study, we aimed to assess the effects of variousMEFVgenotypes on the clinical characteristics of the patients, with a special focus on the joint involvement. In total, 782 patients with FMF were categorized into 3 groups according to theMEFVmutation; Group 1: Patients homozygous for M694V; Group 2: Patients carrying other pathogenic MEFV variants in exon 10 in homozygous or compound heterozygous states; and Group 3: FMF patients with other variants or without mutations. Clinical and demographic findings were compared between groups. Among the 782 FMF patients, total frequency of arthritis was 237 (30.3%): 207 (26.4%) were acute monoarthritis and 67 (8.5%) were chronic arthritis. Both the frequency of arthritis (acute and/or chronic) (40.4% vs. 24.8% vs. 26.7%; p:0.001) and acute monoarthritis (35.4% vs. 20% vs. 23.7%; p:0.001) were significantly higher in Group 1 than in the other groups. FMF patients with chronic arthritis showed a distinct juvenile idiopathic arthritis (JIA) distribution pattern with a more frequent enthesitis-related arthritis (ERA) subtype (43.2%). HLA-B27 was positive in 24% of the ERA patients.Conclusion: Homozygous M694V mutation is associated with a more frequent and longer acute monoarthritis comparing to otherMEFVgenotypes. In addition, the risk of chronic arthritis seems not related to theMEFVmutations. However, FMF patients with chronic arthritis show a distinct ILAR JIA distribution pattern with a more frequent ERA and undifferentiated arthritis subtype.What is known:• Homozygous M694V mutation is associated with a more frequent and longer acute monoarthritisWhat is new:• FMF patients with chronic arthritis show a distinct ILAR JIA distribution pattern with a more frequent ERA subtype• ERA patients with negative HLA-B27 antigen should also be assessed for polyserositis episodes of FMF, especially in countries with high FMF carrier frequency
The first report of digenean infecting short mackerel (Rastrelliger brachysoma) from Chon Buri Province, the Gulf of Thailand
Authors: Kaenkaew Chanisara , Chan Abigail Hui En , Thaenkham Urusa , Ratnarathorn Napat , Sagulwong Sarid , Pakdee Wallop 
Published: August 2024

AbstractRastrelliger brachysoma (Bleeker, 1851), the short mackerel, is a dietary staple and of significant economic demand in Southeast Asia and Thailand. However, the demand for short mackerel has precipitated an overfishing crisis, leading to a depletion of fish stocks. Overfishing, coupled with parasitism, may result in a decline in the population of R. brachysoma. Digenetic trematode infection is prevalent in marine fish and has a considerable impact on the overall health of the fish. Here, to identify digenetic trematodes infecting R. brachysoma, we aim to determine the identity, prevalence, and intensity of digenean infections in R. brachysoma from the Gulf of Thailand. A total of 194 short mackerel were obtained from Chon Buri Province, where digeneans were isolated and identified. The molecular identity of the digeneans was confirmed using the nuclear 28S rRNA gene. Of the 194 short mackerel, 100% were found to be infected with digeneans, comprising of Lecithocladium, Prodistomum, Opechona, and Aphanurus. Lecithocladium was the most prevalent (98%) and had the highest intensity of infection (37 mean intensity), followed by Prodistomum (75% prevalence and 17 mean intensity). Our study thus presents the first evidence of digeneans infecting the economically important short mackerel from the Gulf of Thailand. The high infection rate of digenetic trematodes may have implications on the health of R. brachysoma, further driving their population decline. These data underscore the importance of safeguarding fisheries resources in the Gulf of Thailand, and downstream conservation efforts are crucial for evidence-based management decisions to safeguard the long-term sustainability of fish resources.
Non-reversible lifts of reversible diffusion processes and relaxation times
Authors: Eberle Andreas , Lörler Francis 
Published: August 2024

AbstractWe propose a new concept of lifts of reversible diffusion processes and show that various well-known non-reversible Markov processes arising in applications are lifts in this sense of simple reversible diffusions. Furthermore, we introduce a concept of non-asymptotic relaxation times and show that these can at most be reduced by a square root through lifting, generalising a related result in discrete time. Finally, we demonstrate how the recently developed approach to quantitative hypocoercivity based on space–time Poincaré inequalities can be rephrased and simplified in the language of lifts and how it can be applied to find optimal lifts.
Kidney transplantation in children and adolescents with C3 glomerulopathy or immune complex membranoproliferative glomerulonephritis: a real-world study within the CERTAIN research network
Authors: Patry Christian , Webb Nicholas J. A. , Feißt Manuel , Krupka Kai , Becker Jan , Bald Martin , Antoniello Benedetta , Bilge Ilmay , Gulhan Bora , Hogan Julien , Kanzelmeyer Nele , Ozkaya Ozan , Büscher Anja , Sellier-Leclerc Anne-Laure , Shenoy Mohan , Weber Lutz T. , Fichtner Alexander , Höcker Britta , Meier Matthias , Tönshoff Burkhard 
Published: August 2024

Abstract
Background
Complement 3 glomerulopathy (C3G) and immune complex membranoproliferative glomerulonephritis (IC-MPGN) are ultra-rare chronic kidney diseases with an overall poor prognosis, with approximately 40–50% of patients progressing to kidney failure within 10 years of diagnosis. C3G is characterized by a high rate of disease recurrence in the transplanted kidney. However, there is a lack of published data on clinical outcomes in the pediatric population following transplantation.

Methods
In this multicenter longitudinal cohort study of the Cooperative European Paediatric Renal Transplant Initiative (CERTAIN) registry, we compared the post-transplant outcomes of pediatric patients with C3G (n = 17) or IC-MPGN (n = 3) with a matched case–control group (n = 20).

Results
Eleven of 20 children (55%) with C3G or IC-MPGN experienced a recurrence within 5 years post-transplant. Patients with C3G or IC-MPGN had a 5-year graft survival of 61.4%, which was significantly (P = 0.029) lower than the 5-year graft survival of 90% in controls; five patients with C3G or IC-MPGN lost their graft due to recurrence during this observation period. Both the 1-year (20%) and the 5-year (42%) rates of biopsy-proven acute rejection episodes were comparable between patients and controls. Complement-targeted therapy with eculizumab, either as prophylaxis or treatment, did not appear to be effective.

Conclusions
These data in pediatric patients with C3G or IC-MPGN show a high risk of post-transplant disease recurrence (55%) and a significantly lower 5-year graft survival compared to matched controls with other primary kidney diseases. These data underscore the need for post-transplant patients for effective and specific therapies that target the underlying disease mechanism.

Graphical abstract
Techno-economic assessment of waste heat recovery for green hydrogen production: a simulation study
Authors: Frassl Natalie , Sistani Nina Ranjbar , Wimmer Yannick , Kapeller Judith , Maggauer Klara , Kathan Johannes 
Published: August 2024

AbstractThe demand for hydrogen as a green energy carrier is increasing as energy sources shift towards sustainable solutions. Alkaline electrolysers offer a clean method to produce hydrogen, though their limited efficiency results in significant energy loss. This study explores the potential to enhance electrolyser efficiency through waste heat recovery. It examines the technical and economic aspects of using excess heat from an alkaline electrolyser, powered by surplus renewable energy, as a feed-in source for district heating. Utilising a simulation framework for renewable power plants, the study integrates a validated electrolyser model. The analysis focuses on the impact of heat utilisation and heat sales on system efficiency, economic viability, and hydrogen pricing. Findings show improved efficiency with heat supply, especially for smaller electrolyser configurations. Heat sales lead to a slight reduction in hydrogen costs and the study demonstrates their viability for smaller electrolysers. Additionally, it highlights the need for an advanced cooling strategy for larger systems. Overall, the results underscore the potential of integrating electrolysis with district heating, offering valuable insights for future renewable-powered energy systems.
Supportive care needs after surgery in patients with breast cancer
Authors: Rizalar Selda , Hamarat Elif , Goktas Sonay 
Published: August 2024

Abstract
Purpose
This study aimed to determine supportive care needs and related factors after surgery in patients with breast cancer.

Methods
This cross-sectional study was conducted with 98 breast cancer patients in a Training and Research Hospital in Istanbul between September 2022 and November 2023. The Personal Information Form and the Supportive Care Needs Survey Short Form Turkish version were used to collect data. One-way variance analysis, post hoc (Tukey, LSD), and t-test were used to analyze the data.

Results
The total scale mean score for women who underwent surgery for breast cancer in the study was 83.95 22.97. Statistically significantly higher total scale scores were observed in younger women and those who received chemotherapy and radiotherapy than in others. The mean physical and daily living subscale scores of those who received chemotherapy and radiotherapy were higher than those who did not (p < .05). The psychology subscale mean scores of those who were young and unemployed were higher than the others (p < .05). The mean sexuality scores of those who were young, those with high education levels, and those who received chemotherapy were higher than the other groups (p < .05). Age factor affects SCN scores in women with breast cancer.

Conclusion
Supportive care needs are higher among women with breast cancer who are younger and receive chemotherapy and radiotherapy. The physical needs of those who receive chemotherapy and radiotherapy, the psychological needs of those who are younger and unemployed, and the need for support regarding sexuality were greater among those who are younger and with higher education. Nurses should be aware of the specific needs of these disadvantaged groups and provide individualized holistic care.
A deep learning LSTM-based approach for AMD classification using OCT images
Authors: Hamid Laila , Elnokrashy Amgad , Abdelhay Ehab H. , Abdelsalam Mohamed M. 
Published: August 2024

AbstractAge-related macular degeneration (AMD) is an age-related, persistent, painless eye disease that impairs central vision. The central area (macula) of the retina, located at the back of the eye, sustains damage that is the cause of loss of vision. The early detection of AMD can increase the probability of treatment and prevent vision loss. The AMD can be classified into dry and wet AMD based on the absence of neovascularization. This study introduces a new methodology for the classification of AMD using optical coherence tomography (OCT) retinal images. The proposed methodology is based on three stages. The first stage is the data preparation stage for resizing and normalizing the used images. The second stage is the image processing stage for enhancing the image quality as contrast and resolution these enhancements have been checked by the weighted peak signal-to-noise ratio (WPSNR) methodology. The third stage is the deep feature extraction and classification stage, which consists of two sub-models. The first model is MobileNet V1 which has been used as a deep feature extractor. The second model is LSTM (long short-term memory), fed with deep features to classify the AMD stages. A multi-classification with six separate trials has been employed with the proposed methodology, and compared with other models like DenseNet201 and InceptionV3. The proposed model has been tested on a sample of benchmark data with 4005 grayscale images labeled into three classes. The proposed methodology has achieved an accuracy of 98.85%, a sensitivity of 99.09%, and a specificity of 99.1%. To ensure the effectiveness of the proposed methodology, a comparative analysis has been established with previous approaches in the related field, and the results demonstrated the superiority of the proposed system in AMD multi-classification.
The hydrogeology of sacred wells: insights from Ireland
Authors: Misstear Bruce , Gill Laurence 
Published: August 2024

AbstractSacred wells and springs are important cultural features in many societies. A recent study in Ireland may be the first detailed countrywide investigation of the hydrogeology and water chemistry of sacred wells. Key findings are discussed in relation to case studies elsewhere. A wide range of hydrogeological settings are represented. There is evidence of anthropogenic impacts at many sacred springs and wells. Communication of potential health impacts is necessary but challenging, because of the sensitivities surrounding these sacred water sources.