bluuebunny/crossref_metadata_2025_split huggingface dataset:
1117 – Psychopathological Dimensions Of Burn Out Syndrome: Depression And Anxiety Correlates
Authors: Stoyanov D.S. , Hristozova S. , Arabadziev Z. , Tilov B.G. 
Published: July 2013

Burn out syndrome (BOS) is considered as a major issue for stress-related professions, with severe clinical and management implications. According to Maslach BOS is manifested with: emotional exhaustion (EE), depersonalization (DP) and low personal accomplishment (PA). Our recent studies have revealed links between personality, psychological climate and vulnerability to burn out (Stoyanov and Cloninger 2011, Tilov et al.2012, Raycheva et al. 2012). At the same time there is growing awareness of the psychopathological features of burn out, considered by some authors as clinical depression (Acker, 2011).The present study aims at comprehensive assessment of the psychopathological correlates of burn out, more specifically depression and anxiety.We have employed the self-assessment questionnaire for depression and anxiety of T. Tashev (DAQ) and Maslach Burnout Inventory (MBI) as standardized for Bulgarian population. DAQ is composed of the following pertinent to our objective scales: general anxiety (GA), vegetative (V); obsessive (O) and depressive (D); MBI is based on the dimensions EE, DP and PA. Our study consists of 70 employees from the system of health care and medical education. The statistical analysis has been performed according to the method of Spearman.The results reveal significant positive correlations of GA, V, D, O from DAQ with EE and DP from MBI and negative correlations of the DAQ scales with PA.It confirms the hypothesis that BOS has clinical manifestations consistent with measures for depression and anxiety disorders. However these trends may indicate the presence of the initial stage of BOS - “flame out”.
1118 – The Impact Of Intra- And Postoperative Albumin Levels As a Biomarker Of Delirium After Cardiopulmonary Bypass: Results Of An Exploratory Study
Authors: Baranyi A. , Rothenhäusler H.-B. 
Published: July 2013

IntroductionDelirium is a frequently under-recognized finding in post-cardiopulmonary bypass patients that is potentially reversible but often associated with short-term complications, increased mortality and prolonged hospitalisation.AimsIn this prospective study the frequency of delirium after cardiac surgery with cardiopulmonary bypass (CPB) was determined. Furthermore, we investigated the impact of intra- and postoperative levels of albumin as a biomarker of delirium.Methods34 patients who underwent elective CPB at the Department of Cardiac Surgery, Ludwig-Maximilians-University of Munich, Germany, were enrolled in this prospective study. During the Intensive Care Unit (ICU) stay and shortly after discharge from the ICU, delirious state was evaluated daily using the Delirium-Rating-Scale. Albumin was assayed preanaesthesia, immediately after induction of anaesthesia, at the beginning of the heart-lung-apparatus period, immediately before the opening and 5 minutes after the opening of the aortic clamp, 24h and 48h postoperatively and on the day before discharge.ResultsAfter CPB, a clinical significant delirious state was observed in 11 patients (32.4%). The albumin level decreased during the surgical intervention and increased postoperatively with a maximum level at the time of discharge. CPB patients with delirious state showed a significantly lower albumin level 24h and 48h postoperatively than those without delirium.ConclusionsA postoperative delirium is a frequently observed finding in post-CPB patients. A low levels of postoperative albumin seems to be an useful biomarker to identify patients with high risk of delirious state after CPB.
1121 – Effects On Cognitive Function In Treatment Resistant Bipolar Depression: Ect Compared To Algorithm Based Pharmacological Treatment
Authors: Kessler U. , Schoeyen H.K. , Andreassen O.A. , Eide G.E. , Hammar Å. , Malt U.F. , Oedegaard K.J. , Morken G. , Sundet K. , Vaaler A.E. 
Published: July 2013

IntroductionElectroconvulsive therapy (ECT) is a treatment alternative in bipolar disorder (BD) depression. Cognitive side effects are the major concern limiting its use.ObjectivesWe present data from the Norwegian randomized controlled trial of ECT in treatment resistant depression in bipolar disorder.AimsTo compare effects on cognitive function of ECT or algorithm based pharmacological treatment at the end of a six-week acute, BD depression treatment trial.MethodsProspective, randomised controlled multi-centre, six-week acute treatment trial. Pre- and post-treatment assessments with the MATRICS Consensus Cognitive Battery (MCCB); a neuropsychological test battery designed to be sensitive to changes in cognitive function.SampleN = 51 patients ≥ 18 years fulfilling criteria for treatment resistant BD depression (MADRS score ≥ 25).InterventionECT group: Three sessions per week for up to six weeks, total up to 18 sessions, and right unilateral electrode placement. Algorithm-based pharmacological treatment group: Based on Goodwin & Jamison, 2007.ResultsBoth groups showed a net gain on MCCB scores without significant differences between the study groups. Mean change in MCCB composite T-score was 4.0 (5.7) in the ECT group and 2.7 (3.6) in the pharmacological group (F = 0.78, eta2 = 0.021, p = 0.383).ConclusionIn treatment resistant BD depression ECT and algorithm-based pharmacological treatment have comparable effects on cognitive function assessed with the MATRICS.
1124 – A Multicentric, Retrospective Data Collection From Patients Diagnosed With Schizophrenia Switched To Solian® In Romanian Practice- switch Study
Authors: Vasile D. , Vasiliu O. , Mangalagiu A.G. , Petrescu B.M. 
Published: July 2013

ObjectiveThe primary objective was to assess the reasons for antipsychotics switch to amisulpide and to evaluate the outcome at 6±1 months following the switch from any antipsychotic drug(s) to amisulpride (Solian®).MethodsThis is an open, non-randomized, multicentric, retrospective, non-interventional study that included 1165 subjects who were already stabilized on amisulpride for at least 6±1 months. These patients were previously switched from other antipsychotic to Solian®. Data were collected retrospectively on the patients’ status 6±1 months ago and their present status.ResultsReasons for switching previous antipsychotic treatment: inadequate control of symptoms in 79.3% of the patients, relapse of the disease under treatment 54.5%, adverse reactions 61.9%, reduced compliance 49.1%, comorbities 7.7%, patients request 28%, family request 24.5%, high cost 1.8%. Reasons for choosing Solian®: quality of life improvement 20.3%, cognitive function preservation 18.7%, better efficacy on positive symptoms 18.7%, better efficacy on negative symptoms 15.1%, low risk of extrapyramidal symptoms 12.3%, reduced weight gain 9.8%, minimal interactions with other drugs 4.2%. The compliance was significantly improved (61%), moderately improved (16%), unchanged (7.6%). Adverse reactions were significantly improved (53.5%), moderately improved (18.5%), unchanged (8.9%), minimum worsening (0.2%), medium worsening (0.1%). The efficacy was significantly improved (69.8%), moderately improved (19.2%), unchanged (2.2%), minimum worsening (0.1%).ConclusionsThe main reasons for antipsychotic switch were the inadequate control of symptoms, relapse of the disease under treatment and adverse reactions. Psychiatrists’ evaluation of the switch outcome at 6±1 months following the switch underlined significant improvement of compliance, adverse reactions and treatment efficacy.
1126 – The Efficacy Of Social Skills Training Over Self-image Distorsions In Avoidant Personality Disorder
Authors: Vasile D. , Vasiliu O. , Mangalagiu A.G. , Blandu M. , Magazin O. 
Published: July 2013

BackgroundThe lack of social skills and self-image distorsions are frequently met in the avoidant personality disorder (APD) and although the personality disorders are egosyntonic, subjects could experience prolonged dysforic episodes and a will to change their relationship patterns.ObjectiveTo evaluate the efficacy of social skills training on the overall APD features and on the self-image distorsions, in particular.MethodsA group of 12 subjects with APD, diagnosed using Structured Clinical Interview for Axis II Disorders of DSM IV (SCID II), were included in a psychotherapy program focused on social skills training with 2 sessions per week, for 3 months, with a follow-up visit after 6 months from baseline. These patients were included in an individual therapy (12 sessions) and group therapy (12 sessions). All of these subjects were monitored using a semi-structured interview focused upon the avoidant-type cognitive schemata and self-image related automatic cognitions. A diary was held by every patient and cognitive restructuring was monitored, as well as the effect of role-playing, imaginative and in vivo exposures.ResultsThe social skills training decreased the occurrence of social exposure associated discomfort, self-image self-reported automatic cognitions (as reflected by the diary entries). The overall evolution reflected an increase in self-confidence and a more stable sense of self in relationships, although the SCID II confirmed the maintenance of the APD diagnosis at follow-up visit.ConclusionsSocial skills training has a positive impact over the self-image, decreasing the social exposure discomfort and inadequacy feelings in the patient relationships.
1139 – Reactive Attachment Disorder: Effects And Limits On Treatment Options
Authors: Zuber N. , Durham M. 
Published: July 2013

The failure to bond with a caring adult can lead to failed bonding in future relationships throughout life. This inability to relate or connect to others may affect the child's development. More and more children are being diagnosed with reactive attachment disorder due to affective instability related to their inability to make secure attachments. The diagnosis is complex and treatments are limited which presents a challenge for providers and patients alike.ObjectivesDescribe cases related to reactive attachment disorder.Describe diagnosis of reactive attachment disorder and its limitations.Describe treatment options for reactive attachment disorder.AimsBe familiar with diagnosis of reactive attachment disorder.Be familiar with treatment options.Be familiar with challenges in complex scenarios.MethodsCase of a 15 year old black female with history of neglect, legal issues, school truancy, witness to domestic and community violence who presents with escalating aggressive behavior and affective instability.Literature review focusing on treatments options in complex scenarios.ResultsMany children are suffering from “maltreatment” and there are difficulties with making an appropriate diagnosis due to co-occurring symptoms and potential differential diagnoses; therefore treatments are limited.ConclusionsThe disorder warrants further research especially in addressing the timing and critical period for an intervention. The disorder necessitates a multi-modal approach in particular a collaborative approach involving in home services with the child and caregiver. The disorder becomes even more complex when dealing with patient populations with intergenerational adversity and the patterns of disordered attachment are evident.
1150 – The Relationship Between Temperament And Character Pattern With Migraine In Patients With Migraine Headache And Control Group
Authors: Sadramely M. , Nilipour M. , Naji F. 
Published: July 2013

IntroductionAmong the causes of headache, migraine headache are most common. Migraine is most common referrals to neurology clinics in all human societies. Today it is confirmed that many of chronic headache is associated with psychological and behavioral problems. Personality is defined as the capacity of individual protest :and temperament &character are subsets of personality. TCI(temperament &character Inventory)is a questionnaire that evaluate these dimensions.The relationship between temperament and migraine were also considered.ObjectivesTo evaluate The relationship between temperament and character pattern with migraineAimsTo provide information for psychiatrists, neurologists and other clinician to aware of this relationship.MethodsThis is a prospective case control study which was done on 63 migraine patients as case group and 63 controls. TCI was used for evaluation.ResultsIn case group the average score in patients were: Novelty seeking 41.51,mean Harm avoidance was 52.16 and Reward dependence 62.14. The average score of Selfdirectedness was 53.14, cooperativness 78.45, Preseverence 63.21 and Selftranscedence was 60.95.In control group the average score in patients were: Novelty seeking 44.77,mean Harm avoidance was 49.28 and reward dependence 62.42.The average score of Selfdirectedness was 54.81,Harm avoidance 73.92, Preseverence 54.09 and Selftranscedence was 62.42.Harm avoidance and Cooperativness had a significant difference between groups(P ha=0/048, P co=0/043).ConclusionsResults showed a significant difference between groups in HA and CO. We can conclude that migraine patients had a higher score in HA and CO subsets. HA is related to serotonergic system and this results presents the role of serotonin in migraine pathology, This shows the role of serotonin in the incidence of HA in migraine patients.
1151 – Clinicians’ Attitudes Toward The Use Of Long-acting Injectable Antipsychotics
Authors: Samalin L. , Charpeaud T. , Heres S. , Llorca P.-M. 
Published: July 2013

IntroductionIn schizophrenia, depot formulations are not widely used in everyday practice. Clinicians’ attitudes play a major role in this low level of use of Long Acting Injectable (LAI). As a consequence, only 35% of patients declare to be well- informed about those formulations.ObjectivesThis study aims to assess psychiatrists’ attitudes toward the use of long-acting injectable antipsychotics in schizophrenia.MethodsDuring the French Congress of Psychiatry (November 2010, Lyon), we interviewed 113 psychiatrists about the factors that influenced their prescription of LAI. We used a structured interview, adapted from the two questionnaires developed by Heres et al. in two studies about the attitudes of German Psychiatrists. Multidimensional and cluster analyses were performed to identify correlations.ResultsHazard risk for others, depot experienced, non-compliance and relapse in the past incited psychiatrists to prescribe LAI antipsychotic. Two different clusters of patients were identified: cluster I corresponded to patients with a past history of relapse and poor compliance and cluster II corresponded to patients with a high level of insight and of therapeutic alliance. The most important factor against the use of LAI was a sufficient estimated compliance with the oral formulation. The risk of extrapyramidal symptoms is, in our sample, one of the main reasons for a limited use of depot neuroleptic.ConclusionsMost factors influencing clinicians’ attitudes toward the use of LAI are shared in many countries. Some attitudes related to organisational aspects, particularly the relevance of healthcare costs may vary from one country to another.
1157 – Diet Behaviors And Danger Of Developing Eating Disorders In School Students
Authors: Szczegielniak A. , Pałka K. , Krysta K. , Krupka-Matuszczyk I. 
Published: July 2013

IntroductionThe problem of eating disorder is increasingly affecting teenagers in Polish schools. This phenomenon needs to be screened and analyzed to allow early detection and diagnosis and providing proper treatment.ObjectivesThe purpose of the study was to assess the correlation between school students’ results in EAT-26 self-report questionnaire and their daily diet behavior and to analyze the occurrence of eating disorders among students in Silesian schools.MethodsOur survey was based on the EAT-26 (Eating Attitude Test) and Behavioral Four Questions Test. 150 questionnaires were given to students of Secondary Schools, 116 were filled out properly. The interviewed group consisted of 85 girls and 31 boys. Average age was 17,24 +/- 1,18. All of the data were analyzed statistically.ResultsAverage BMI was 21,06; half of the recruited subjects had correct BMI whereas over 40% of them presented underweight. Within 116 responses from the EAT-26 nearly 93% were the a group of the small risk of the future eating disorders. Nevertheless, over 6% of survey participants were in the group of the high risk. In the Behavioral Four Questions Test 10% were in the compulsive overeating group, others in the group of a probable development of anorexia (7%) or bulimia nervosa (3%).ConclusionsSpecific socio-cultural factors are challenging for the public service- both, in terms of health promotion programs and the organization of free after school hours.
1158 – A Morphologically Based Scale Of Alzheimer’s Disease Stages “the Tomography Dementia Rating Scale” (tdr)
Authors: Maksimovich I.V. 
Published: July 2013

IntroductionTo identify AD stages, we propose morphologically determined “Tomography Dementia Rating scale (TDR)” based on the determination of dementia stages according to the severity of atrophic changes in the temporal lobes obtained during CT or MRI.MethodsThe research included 81 patients aged 34–79 (average age 67), 28 male (34.57%), 53 female (65.43%), with AD different stages.All the patients underwent MRI, CT with subsequent calculation of the temporal lobes atrophy degree.ResultsCT and MRI showed that objective brain morphological features characteristic for all patients with AD are atrophic changes in the temporal lobes, which at AD different stages range from 4 to 62%. These data made it possible to set up a scale that allows to identify certain atrophic changes at each disease stage:Preclinical AD stage - TDR-0 - temporal lobes atrophy with 4–8% tissue mass decrease.Early AD stage - mild dementia - TDR-1 - temporal lobes atrophy with 9–18% tissue mass decrease (corresponds to CDR-1).Middle AD stage - mild dementia - TDR-2 - temporal lobes atrophy with 19–32% tissue mass decrease (corresponds to CDR-2).Late AD stage - severe dementia - TDR-3 - temporal lobes atrophy with 33–62% tissue mass decrease (corresponds to CDR-3).ConclusionsThe application of morphologically determined AD stages scale - TDR - is an effective method to objectively identify AD stages by means of widespread CT and MRI.
1159 – Description Of The Brain Functional Connectivity Across Sleep Stages Using a Coherence Analysis
Authors: Jurysta F. , Van Wettere L. , Lanquart J.-P. , Linkowski P. , Marinazzo D. 
Published: July 2013

ObjectivesThe statistical dependencies among even remote brain regions are reflected by the functional connectivity. We studied the functional brain network across sleep stages for each relevant sleep EEG frequency band.MethodsNine healthy young subjects without somatic, psychiatric and sleep disorders were recruited. Sleep stages were defined in accordance with the Rechtschaffen and Kales criteria. The first 20 epochs of each sleep stage (Wake, stages 1 to 4 and REM sleep) were used for analysis in regard of specific sleep EEG frequencies as delta, theta, alpha, sigma and beta. Coherence analysis was applied between each electrode and each other of the 19 EEG electrodes.ResultsCoherence analysis showed high values within the same hemisphere at wake and sleep stage 1. During stages 2, 3 and 4 and REM sleep, high correlations were extended to more regions, particularly for slow oscillations. In delta band, coherences values differed between right and left cerebral hemispheres during all sleep stages. In other frequency bands, none differences were observed between both sides. In the right hemisphere, coherence values changed across sleep stages in delta frequency but remained unchanged for other sleep EEG frequencies. In the left hemisphere, none changes in coherence were observed across sleep stages and each frequency except for sigma and beta.ConclusionsChanges in coherence measurements showed different mapping in the three sleep main states (Wake, NREM and REM sleep) and for sleep EEG frequencies. Further analyses will investigate connectivity across sleep stages transitions and also, in psychiatric conditions.
1168 – A Sample Of Electroconvulsive Therapy Practice From Turkey
Authors: Yazici E. , Hacihanifioglu S.B. , Karabulut U. , Yazici A.B. , Kirpinar I. 
Published: July 2013

ObjectivesWe sought to obtain an overview of electroconvulsive therapy (ECT) practice in Psychiatry Clinic of Derince Research and Training Hospital which has 25 inbeds and is a new kind of governmental administration for new health policy of Turkey.MethodsFrom January 2011 to October 2012, a form enquiring about evaluation of ECT was filled retrospectively.ResultsThe total number of patients, admitted for psychiatry during the survey period was 77012. A total of 82 patients (10.06% among inpatients and 0.106% in all psychiatric admissions) received 514 sessions of ECT from 815 psychiatric inpatients. Seven patients had multiple hospitalizations. Patients with severe depressive episode with/without psychotic symptoms (include bipolar affective disorder current episode severe depression) received ECT most frequently (54.9%), followed by patients with bipolar affective disorder, current episode manic with/without psychotic symptoms (19.5%), schizophrenia (18.3%), and schizoaffective disorders (3.7%) respectively. All of the patients were reported to have insufficient response to medication and 19 patients had suicidalty (23.1%). There were no pregnant patients. All patients received modified ECT. There were no ECT-related deaths or injuries. 5 (6%) patients needed intervention for bradicardia and one patient had hypersensitivity to anesthetic medication during the survey.ConclusionThe majority of patients who received ECT were diagnosed with severe depression with/without psychotic symptoms. Suicidalty and insufficient response to medication had an important role at decision of ECT. These results suggest that ECT is still safe and assumes an important role in daily practice of inpatient clinics.
1183 – Deinstitutionalization And Family Burden Following The Psychiatric Reform
Authors: Basta M. , Stefanakis Z. , Panierakis C. , Michalas N. , Zografaki A. , Tsougkou M. , Vgontzas A.N. 
Published: July 2013

IntroductionDeinstitutionalization in Crete and the closure of the only Psychiatric Hospital in 2006, has resulted in a significant shift of treatment options that were available for chronic psychiatric patients. Specifically, psychiatric care shifted from long-term or even lifetime hospitalization, to short-term hospitalization and community-based treatment.ObjectiveTo examine the residential/occupational status of the patients discharged from the Psychiatric Hospital after its closure and the profile of residence, psychiatric profile and sociodemographic data of inpatients of the Psychiatric Department of the University Hospital of Crete (PD/UHC).AimTo explore the burden of family members living in the same home with chronic psychiatric patients.MethodWe examined the residence status of the patients discharged from the Psychiatric Hospital. Furthermore, we examined the psychiatric profile and sociodemographic data from 400 inpatients that were admitted between Nov 2011 and August 2012 in the PD/UHC. We analyzed the data by using frequencies.ResultsAmong Psychiatric Hospital residents, 72% returned home after its closure, while 2.5% were referred to community services. Among psychiatric inpatients, 82,9% return home after discharge. From a subset of 212 patients, 64% live with their own/paternal families, while 24.5% live alone, and 63% of patients living with family/relatives, remain unemployed/on welfare.ConclusionsPsychiatric reform and inadequate community-based psychiatric services, has resulted in an increasing family burden, since most psychiatric patients remain unemployed, under the care of their family. There is a need for development of community-based services to provide care and assistance to chronic patients and their families.