bluuebunny/crossref_metadata_2025_split huggingface dataset:
Simultaneous removal of endotoxins, inflammatory mediators and uremic toxins in ICU patients with septic shock: a retrospective cohort study
Authors: Theisen Benjamin E. , Lichtenstern Christoph , Nusshag Christian , Tan Benjamin , Hölle Tobias , Weigand Markus A. , Kalenka Armin , Fiedler-Kalenka Mascha O. 
Published: August 2024

AbstractSepsis, one of the leading causes of death, is still lacking specific treatment. OXIRIS (BAXTER, Deerfield, IL, USA) is the first device allowing combined removal of endotoxins, inflammatory mediators and uremic toxins, alongside fluid balance control. Available data is very limited. This retrospective propensity score-matched cohort study of adult patients with septic shock aimed to evaluate septic shock duration and mortality in patients treated with either standard of care renal replacement therapy (RRT) or RRT with combined hemoadsorption, who were admitted to the interdisciplinary surgical intensive care unit at Heidelberg University Hospital during the years 2018 through 2021. Main outcomes were duration of shock, thirty-day mortality and plasma interleukin-6 levels before and after initiation of hemoadsorption. Included were 117 patients (female, 33%; male 67%); median age: 67 (16) years. After matching: 42 patients (female, 33%; male, 67%); mean age: 59.1 ± 13.8 years. There was no statistically significant difference in septic shock duration (p = 0.94; hazard ratio (HR) 0.97 (95% CI, 0.48–1.97)). Thirty-day survival analysis showed a non-statistically significant survival difference. (p = 0.063; HR 0.43 (95% CI, 0.17–1.09)). A post-hoc 90-day survival analysis revealed statistically significant longer survival and lower death hazard ratio in patients treated with RRT + HA (p = 0.037; HR = 0.42 (95% CI, 0.18–0.99). In conclusion, RRT with combined hemoadsorption of endotoxins, inflammatory mediators and uremic toxins is a modality worth further investigation.
Transcriptome profiling of pediatric extracranial solid tumors and lymphomas enables rapid low-cost diagnostic classification
Authors: Opoku Kofi B. , Santiago Teresa , Kumar Priya , Roush Sophia M. , Fedoriw Yuri , Tomoka Tamiwe , Leventaki Vasiliki , Furtado Larissa V. , Bhakta Nickhill , Alexander Thomas B. , Wang Jeremy R. 
Published: August 2024

AbstractApproximately 80% of pediatric tumors occur in low- and middle-income countries (LMIC), where diagnostic tools essential for treatment decisions are often unavailable or incomplete. Development of cost-effective molecular diagnostics will help bridge the cancer diagnostic gap and ultimately improve pediatric cancer outcomes in LMIC settings. We investigated the feasibility of using nanopore whole transcriptome sequencing on formalin-fixed paraffin embedded (FFPE)-derived RNA and a composite machine learning model for pediatric solid tumor diagnosis. Transcriptome cDNA sequencing was performed on a heterogenous set of 221 FFPE and 32 fresh frozen pediatric solid tumor and lymphoma specimens on Oxford Nanopore Technologies’ sequencing platforms. A composite machine learning model was then used to classify transcriptional profiles into clinically actionable tumor types and subtypes. In total, 95.6% and 89.7% of pediatric solid tumors and lymphoma specimens were correctly classified, respectively. 71.5% of pediatric solid tumors had prediction probabilities > 0.8 and were classified with 100% accuracy. Similarly, for lymphomas, 72.4% of samples that had prediction probabilities > 0.6 were classified with 97.6% accuracy. Additionally, FOXO1 fusion status was predicted accurately for 97.4% of rhabdomyosarcomas and MYCN amplification was predicted with 88% accuracy in neuroblastoma. Whole transcriptome sequencing from FFPE-derived pediatric solid tumor and lymphoma samples has the potential to provide clinical classification of both tissue lineage and core genomic classification. Further expansion, refinement, and validation of this approach is necessary to explore whether this technology could be part of the solution of addressing the diagnostic limitations in LMIC.
Sexual dimorphism in the structural colours of the wings of the black soldier fly (BSF) Hermetia illucens (Diptera: Stratiomyidae)
Authors: Rebora Manuela , Piersanti Silvana , Romani Aldo , Kovalev Alexander , Gorb Stanislav , Salerno Gianandrea 
Published: August 2024

AbstractThe black soldier fly (BSF) Hermetia illucens (Diptera: Stratiomyidae) plays a significant role at the larval stage in the circular economy due to its ability to convert organic waste into valuable products for energy, food, feed, and agricultural applications. Many data are available on larval development and biomass generation, but basic research on this species is lacking and little is known about adult biology, in particular about the cues involved in sexual recognition. In the present study, using various instruments (stereomicroscope, scanning and transmission electron microscope, hyperspectral camera and spectrophotometer), wing ultrastructure of both sexes was analysed, reflectance and transmission spectra of the wings were measured and behavioural bioassays were carried out to measure male response to specific visual stimuli. The collected data showed the existence of sexual dimorphism in the wings of H. illucens due to iridescent structural colouration generated by a multilayer of melanin located in the dorsal lamina of the central part of the wing. Wing sexual dimorphism is particularly evident regarding the strong emission of blue light of female wings. Blue colour induces in males a strong motivation to mate. The obtained results can help to improve and optimize the breeding techniques of BSF.
Photodynamic therapy with NIR-II probes: review on state-of-the-art tools and strategies
Authors: Yang Yiqian , Jiang Shaohua , Stanciu Stefan G. , Peng Hao , Wu Aiguo , Yang Fang 
Published: August 2024

The current state-of-the art on NIR-II-activated photosensitizers and their applications for the deep tumor treatment, as well as recent efforts that combine NIR-II activated PDT with other complementary therapeutic routes.
A method for simulating powdering of silicone rubber composite insulator in coastal areas
Authors: Liang Tian , Zhang Zhijin , Jiang Xingliang , Hu Jianlin , Hu Qin 
Published: August 2024

AbstractIn recent years, the powdering phenomenon often has been found in suspension composite insulators operating in outdoor environments, and there is currently a gap in research on the composition and formation process of powdered substance. A method for simulating powdering of silicone rubber (SiR) in a high humidity salt‐fog environment is proposed, and the obtained powder is compared with the natural powder. Test results show that the powder obtained from artificial environments is similar to the natural powder in coastal areas, which proves that this method is reasonable to simulate the powdering process. Powdered substances are generally composed of two types of substances, Type I is an inorganic filler and its dehydration product and Type II is a small molecular siloxane. The average particle size of artificial powder is 8–10 μm, while that of natural powder is 3–5 μm. All the dielectric properties of powdered SiR decreased, and after 12 h of ageing, the dielectric properties of the artificial sample were close to those in coastal areas, and the element composition was also similar. Aluminium hydroxide (Al(OH)3) crystals were detected in both powders. The change trend of the characteristic functional groups in the infrared spectrum of the artificial powder is consistent with that of the natural powder, but the degree of molecular chain bond destruction is lower.
Improved protection for colour images via invertible colour‐to‐grey, image distortion, and visible‐imperceptible watermarking
Authors: Fragoso‐Navarro Eduardo , Garcia‐Ugalde Francisco , Cedillo‐Hernandez Manuel 
Published: August 2024

AbstractInvertible colour‐to‐grey algorithms protect the colour of an image against illegal usage and distribution. These schemes hide the colour information into a grayscale version of the image, making colour recovery without proper authorization challenging. A previous study proposed the incorporation of content security by distorting the protected image to hinder illegal structure restoration. This work addresses the limitations of this method, significantly improving both processing time and the quality of the recovered colour image. Specifically, processing times are reduced from 45 h to 9 s, and the mean PSNR value is increased by up to 2.23 dB. Furthermore, this proposal achieves competitive results compared to existing approaches that do not implement content security, obtaining mean peak signal‐to‐noise ratio (PSNR) and structural similarity index measure (SSIM) values above 42.32 dB and 0.992, respectively. Finally, quantitative results are supported by visual comparisons.
Swin‐fisheye: Object detection for fisheye images
Authors: Zhang Dawei , Yang Tingting , Zhao Bokai 
Published: August 2024

AbstractFisheye cameras have been widely used in autonomous navigation, visual surveillance, and automatic driving. Due to severe geometric distortion, fisheye images cannot be processed effectively by conventional methods. The existing object detection algorithms cannot better detect the small targets or the objects with large distortion in the fisheye images. The size and scene of available fisheye datasets (such as WoodScape and VOC‐360) cannot satisfy the training of robust network models. Herein, the authors propose Swin‐Fisheye, an end‐to‐end object detection algorithm based on Swin Transformer. A feature pyramid module based on deformable convolution (DFPM) is designed to obtain richer contextual information from the multi‐scale feature maps. In addition, a projection transformation algorithm (PTA) is proposed, which can convert rectilinear images into fisheye images more accurately, and then create a fisheye image dataset (COCO‐Fish). The results of extensive experiments conducted on VOC‐360, WoodScape, and COCO‐Fish demonstrate that the proposed algorithm can achieve satisfactory results compared with state‐of‐the‐art methods.
SARO‐MB3‐BiGRU: A novel model for short‐term traffic flow forecasting in the context of big data
Authors: Wang Haoxu , Wang Zhiwen , Li Long , Yang Kangkang , Zeng Jingxiao , Zhao Yibin , Zhang Jindou 
Published: August 2024

AbstractIn order to further improve the accuracy of short‐term traffic flow prediction on designated sections of highways, a combined prediction model is designed in this paper to predict the traffic flow on designated sections of highways. Firstly, for the shortcomings of artificial rabbits optimization (ARO) algorithm, sine cosine ARO (SARO) is proposed by incorporating sine cosine algorithm (SCA) idea into ARO, and introducing the non‐linear sinusoidal learning factor. Secondly, three mobile inverted bottleneck convolution (MBConv) modules are utilized to form the MB3 module, and with BiGRU are utilized to form the MB3‐BiGRU combined prediction model. Finally, the MB3‐BiGRU model is optimized by SARO to achieve short‐term prediction of traffic flow. The analysis results show that using the United Kingdom highway dataset as the data source, the SARO‐MB3‐BiGRU presented in this paper reduces the root mean squared error (RMSE) by 32.58%, the mean absolute error (MAE) by 30.25%, and the decision coefficient (R2) reaches 0.96729, as compared to BiGRU. Compared with other common models and algorithms, the SARO has good solving capabilities and versatility, and the SARO‐MB3‐BiGRU model has been greatly improved in terms of prediction accuracy and generalization ability, which has better prediction ability and engineering reference value.
EndoFLIP Use in De Novo and Revisional Foregut Surgery
Authors: Colvin Jennifer S. , Imbus Joseph , Wadhwa Neha 
Published: August 2024

AbstractEndoFLIP technology, utilizing impedance planimetry, has revolutionized the assessment of gastrointestinal sphincters by providing real-time measurements of cross-sectional area and pressure to calculate distensibility. This review explores its application in de novo and revisional foregut surgeries. Preoperatively, EndoFLIP has demonstrated efficacy in evaluating gastroesophageal reflux disease, hiatal hernia, and esophageal motility disorders, including achalasia, by distinguishing motility patterns and identifying sphincter incompetence. In gastroparesis, EndoFLIP's measurement of pyloric distensibility correlates with gastric emptying and symptom severity, guiding therapeutic decisions for pyloric interventions. Intraoperatively, EndoFLIP optimizes surgical outcomes in antireflux procedures, such as fundoplication and hiatal hernia repairs, by balancing effective reflux control with minimizing postoperative complications like dysphagia and gas bloat. For esophageal myotomy, including Heller myotomy and per oral endoscopic myotomy, EndoFLIP ensures adequate sphincter relaxation, reducing reflux risks. Additionally, during endoscopic pyloromyotomy for gastroparesis, EndoFLIP predicts clinical success by assessing postprocedural distensibility. While promising, further research is essential to establish standardized intraoperative protocols and ideal measurement targets, enhancing the reproducibility and accuracy of EndoFLIP applications. Overall, EndoFLIP offers a significant advancement in foregut surgery, improving diagnostic precision and therapeutic outcomes.
Low-Compared with High-Dose Regimen of Induction Chemotherapy in Locally Advanced Nasopharyngeal Cancer: A Systematic Review and Meta-analysis
Authors: Kurniawan Andree , Cahyanur Rahmat , Giselvania Angela , Tancherla Angeline , Wijovi Felix , Halim Devina Adella , Sari Chandra , Amelia Devi Astri Rivera , Djatnika Deden , Nasution Muhammad Arman , Siregar Nia Novianti , Dewi Ni Putu Merlynda Pusvita , Noor Muhammad Nanda , Purlikasari Nugraheny Prasasti , Sinurat Julfreser , Sugianto Galuh Chandra Kirana , Sitompul Yohana , Kurniawan Robby , Wisman Beta Agustia , Syarifuddin Faisal , Ardian Ardi 
Published: August 2024

Introduction International recommendation supports induction chemotherapy (IC) followed by concurrent chemoradiotherapy (CCRT) as a new standard of care for locally advanced nasopharyngeal cancer (LA-NPC) which give a survival benefit. TPF is one of the IC regimens which consists of docetaxel (75 mg/m2, 1 hour infusion), cisplatin (75 mg/m2, 0.5–3 hours), and 5-fluorouracil (600 mg/m2, 4 days). Previous retrospective study in Chinese population reported low-dose TPF (L-TPF), consists of docetaxel (60 mg/m2), cisplatin (65 mg/m2), and then 5-fluorouracil (550 mg/m2/d; 5 days), showed better tolerance and compliance rates, with similar efficacy to high-dose TPF (H-TPF). Thus, we aim to evaluate the current evidence of the effect of L-TPF compared with H-TPF on survival and tolerance as IC in LA-NPC.
Methods Data were collected from PubMed, PubMed Central, and Science Direct, using combinations of keywords related to neoadjuvant chemotherapy (NAC) or IC, TPF dose regimen, and LA-NPC. The included studies investigated the efficacy and toxicity of IC with a TPF regimen. The quality of each included study was assessed using the Newcastle–Ottawa scale for cohort studies and the JADAD scale for randomized controlled trial (RCT). Only moderate- and good-quality studies were further evaluated in the meta-analysis.
Results A total of six studies consisting of 509 NAC patients were included. All the studies evaluated overall survival (OS) and progression-free survival (PFS). Quantitative analysis showed that L-TPF + CCRT significantly showed good OS (hazard ratio [HR] = 0.50; 95% confidence interval [CI], 0.33–0.76; p = 0.001) but not PFS (HR = 0.45; 95% CI, 0.16–1.25; p = 0.13). Common chemotoxicities that were found in both groups were neutropenia and anemia.
Conclusion L-TPF IC had a significant positive effect on the survival of LA-NPC patients. Further, larger multicenter RCT studies are needed to focus on evaluating the optimal TPF regimen dose in LA-NPC.
Thermal quantum correlations and disorder in a fermionic system described by the extended Fermi–Hubbard-like model
Authors: Essakhi Mohamed , Mansour Mostafa 
Published: August 2024

Abstract
This research investigates thermal quantum correlations in a fermionic system modeled using an extended Fermi–Hubbard-like model. We examine the impacts of noisy temperature, local chemical potential, and nearest-neighbor interaction. The Fermi–Hubbard model provides a framework for understanding fermion interactions in a lattice and shows potential for simulating fermionic systems with superconducting circuits in quantum simulation. Using the Jordan–Wigner transformation, we convert the fermionic system into a qubit system, bridging quantum information and particle physics. Thermal entanglement is assessed using concurrence measurement, while thermal quantum correlations are measured through trace distance discord and local quantum uncertainty. Our findings indicate that increasing temperature causes disorder, negatively affecting quantum entanglement and correlations. However, by adjusting the nearest-neighbor interaction strength and local potential, we can mitigate thermal noise effects, enhancing correlations and entanglement. Selecting appropriate parameters can ensure the system’s potential for quantum technology development.
Crystal growth, structure and crystal field splitting and fitting of Yb:GdScO3
Authors: Li 李 Jia-Hong 加红 , Zhang 张 Qing-Li 庆礼 , Sun 孙 Gui-Hua 贵花 , Gao 高 Jin-Yun 进云 , Dou 窦 Ren-Qin 仁勤 , Wang 王 Xiao-Fei 小飞 , Ding 丁 Shou-Jun 守军 
Published: August 2024

Abstract
A good quality (5 at.% Yb:GdScO3) single crystal of Φ30 mm × 37 mm was grown successfully by the Czochralski method. Its structure is studied by the x-ray diffraction (XRD), and its atomic coordinates are obtained by Rietveld refinement. The crystal field energy level splitting of Yb3+ in GdScO3 is determined by employing the absorption and photoluminescence spectra at 8 K. Only 2F7/2(4) is far from the ground state 2F7/2(1) by 710 cm−1 among the crystal field energy levels split from 2F7/2, so it is more easier to realize the laser operation of 2F5/2(1)→2F7/2(4) with wavelength 1060 nm. The spin–orbit coupling parameters and intrinsic crystal field parameters (CFPs). The intrinsic crystal field parameters

B
¯

k

(k = 2, 4, 6) of the crystal were fitted by the superposition model. The CFPs evaluated with

B
¯

k

and coordination factor are taken as the initial parameters to fit the crystal field energy levels of the crystal, and the crystal field parameters

B
q
k

are obtained finally with the root-mean-square deviation 9 cm−1. It is suggested that the ligand point charge, covalency and overlap interaction are slightly weaker than charge interpenetration and coulomb exchange interaction for Yb3+ in GdScO3. The obtained Hamiltonian parameters can be used to calculate crystal field energy levels and wave functions of Yb:GdScO3 to analyze the mechanism of the luminescence or laser.
Distraction impact of concurrent conversation on event-related potential based brain-computer interfaces
Authors: Kim Minju , Kim Sung-Phil 
Published: August 2024

Abstract

Objective. This study investigates the impact of conversation on the performance of visual event-related potential (ERP)-based brain–computer interfaces (BCIs), considering distractions in real life environment. The research aims to understand how cognitive distractions from speaking and listening activities affect ERP-BCI performance. Approach. The experiment employs a dual-task paradigm where participants control a smart light using visual ERP-BCIs while simultaneously conducting speaking or listening tasks. Main results. The findings reveal that speaking notably degrades BCI accuracy and the amplitude of ERP components, while increases the latency variability of ERP components and occipital alpha power. In contrast, listening and simple syllable repetition tasks have a lesser impact on these variables. The results suggest that speaking activity significantly distracts visual attentional processes critical for BCI operation Significance. This study highlights the need to take distractions by daily conversation into account of the design and implementation of ERP-BCIs.
Research on the synchronization technology of external clock based on gps timing
Authors: Gan Zhifeng 
Published: August 2024

Abstract
In practical applications, communication devices usually use communication message packets to synchronize time through electromagnetic wave transmission. However, due to complex external electromagnetic interference, communication equipment often encounter problems such as time synchronization errors, poor synchronization accuracy, and long synchronization periods through the above synchronization methods. Based on the wide application of GPS in daily life and production, this paper proposes a GPS-based external synchronization technology for communication equipment, which synchronizes the time within the entire network by synchronizing the communication equipment with GPS. The external clock synchronization hardware architecture is introduced, and the external synchronization process is explained in detail. Combined with the characteristics of clock drift, the Kalman filtering algorithm is introduced to track the clock drift. The external synchronization technology based on GPS timing has the advantages of high synchronization accuracy and fast synchronization speed.
Study on the adsorption properties of lysozyme by cellulose microspheres modified with reactive red 120
Authors: Song Yifei , Liang Xiaoyi 
Published: August 2024

Abstract
Microspheres of cellulose acetate, characterized by a multi-layered, uniform, and continuous porous structure, were synthesized through the process of emulsion evaporation. Subsequent deacetylation facilitated the modification of the cellulose microspheres’ surface, which was functionalized with Reactive Red 120, serving as an affinity dye ligand. This modification yielded a cationic adsorbent. The adsorptive behavior of lysozyme from aqueous solutions, with lysozyme designated as the target protein, was examined in relation to the effects of pH and ionic strength. The adsorptive capacity of the cellulose microspheres, modified with Reactive Red 120, for lysozyme was determined to be 106.57 mg g−1, exhibiting rapid equilibration within 40 min. The adsorption kinetics and thermodynamics were accurately described by the pseudo-second-order kinetic model and the Langmuir model, respectively, with correlation coefficients (R2) of 0.98 and 0.97. Furthermore, dynamic adsorption experiments revealed an enhanced adsorption capacity of 36.5 mg g−1, significantly surpassing that of the unmodified microspheres. The cellulose microspheres, derived from cellulose acetate and modified accordingly, are environmentally benign and sustainable, thereby holding significant promise for various biological applications.