bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Rare‐Earth Transition‐Metal Indium Sulfides RE3FeInS7 (RE: La—Pr), RE3CoInS7 (RE: La, Ce), and La3NiInS7.
Authors: Rudyk Brent W. , Stoyko Stanislav S. , Mar Arthur 
Published: January 2014

AbstractThe title compounds are prepared from stoichiometric mixtures of the elements (silica tubes, 1050 °C, 96 h) and characterized by powder and single crystal XRD, XPS, magnetic susceptibility measurements, and TB‐LMTO‐ASA band structure calculations.
ChemInform Abstract: A Novel Yellow‐Emitting SrAlSi4N7:Ce3+ Phosphor for Solid State Lighting: Synthesis, Electronic Structure and Photoluminescence Properties.
Authors: Ruan Jian , Xie Rong‐Jun , Funahashi Shiro , Tanaka Yoshinori , Takeda Takashi , Suehiro Takayuki , Hirosaki Naoto , Li Yuan‐Qiang 
Published: January 2014

AbstractA series of Ce3+‐doped and Ce3+/Li+‐codoped SrAlSi4N7 phase‐pure phosphors are prepared by gas pressure sintering of stoichiometric powder mixtures of Sr3N2, AlN, α‐Si3N4, CeN, and Li3N with a double amount of AlN to avoid the formation of Sr2Si5N8 (1750 °C, 6 h, 0.92 MPa high purity N2).
ChemInform Abstract: Synthesis, Structure, Gas‐Phase Reactivity, and Catalytic Relevance of Trinuclear Mo3S4 Clusters Bearing Terminal Hydroxo and Hydrosulfido Groups.
Authors: Beltran Tomas F. , Feliz Marta , Llusar Rosa , Safont Vicent S. , Vicent Cristian 
Published: January 2014

AbstractThe crystal structures of compounds (III) and (IV) are determined by single crystal XRD.
ChemInform Abstract: An Unstable Paramagnetic Isopolyoxomolybdate Intermediate Non‐Homogeneously Reduced at Different Sites and Trapped in a Host Based on Chemical Adaptability.
Authors: Mueller Achim , et al. et al. 
Published: January 2014

AbstractCompound (II) is characterized by IR, VIS/NIR, and EPR spectroscopy, XRD, and DFT calculations.
ChemInform Abstract: Synthesis and Crystal Structure of (1,3‐Diammoniumpropane)3 [V4W9O40]·H2O.
Authors: Hinz Michael , Naether Christian , Bensch Wolfgang 
Published: January 2014

AbstractThe new tungstovanadate (III) crystallizes in the monoclinic space group P21/m with Z = 2 (single crystal XRD).
ChemInform Abstract: New Layered Iron Sulfide NaFe1.6S2: Synthesis and Characterization.
Authors: Lai Xiaofang , Chen Xiaolong , Jin Shifeng , Wang Gang , Zhou Tingting , Ying Tianping , Zhang Han , Shen Shijie , Wang Wanyan 
Published: January 2014

AbstractA series of compounds NaxFe2‐yS2+z (0.8 ≤ x ≤ 1; 0.3 ≤ y ≤ 0.6; 0 ≤ z ≤ 0.1) is prepared by solid state reaction of the elements (800 °C, 30—48 h).
ChemInform Abstract: Dinuclear Zinc—ProPhenol‐Catalyzed Enantioselective α‐Hydroxyacetate Aldol Reaction with Activated Ester Equivalents.
Authors: Trost Barry M. , Michaelis David J. , Truica Mihai I. 
Published: January 2014

AbstractA dinuclear phenol zinc complex for the asymmetric aldol condensation of α‐hydroxyacetamide (I) is developed.
ChemInform Abstract: C—H Functionalization of Cyclopropanes: A Practical Approach Employing a Picolinamide Auxiliary.
Authors: Roman Daniela Sustac , Charette Andre B. 
Published: January 2014

AbstractThe Pd‐catalyzed C—H arylation of picolinamide‐functionalized cyclopropanes is promoted by either a silver additive or catalytic amounts of pivalic acid in the presence of a carbonate base.
ChemInform Abstract: Carboxylate Assistance for Catalyzed Hydroarylations of Methylenecyclopropanes.
Authors: Schinkel Marvin , Wallbaum Jan , Kozhushkov Sergei I. , Marek Ilan , Ackermann Lutz 
Published: January 2014

AbstractThe use of ruthenium carboxylates as catalysts allows a carboxylate‐assisted chemoselective hydroarylation of strained methylenecyclopropanes with conservation of the cyclopropane ring.
ChemInform Abstract: Synthesis of Polyfluoroalkyl Cyclobutenes from 3‐Aza‐1,5‐enynes via an Aza‐Claisen Rearrangement/Cyclization Cascade.
Authors: Xin Xiaoyi , Wang Dongping , Wu Fan , Wang Chunxiang , Wang Haolong , Li Xincheng , Wan Boshun 
Published: January 2014

AbstractHeating 3‐aza‐1,5‐enynes in dioxane leads to the formation of an allene‐imine intermediate via aza‐Claisen rearrangement.
ChemInform Abstract: Catalytic Enantioselective Amadori—Heyns Rearrangement of Racemic α‐Hydroxy Ketones with Arylamines: Synthesis of Optically Active α‐Arylamino Ketones.
Authors: Frongia Angelo , Secci Francesco , Capitta Francesca , Piras Pier Paolo , Sanna Maria Luisa 
Published: January 2014

AbstractTitle compounds [(III), (V), and (VIII)] are synthesized in good yields and good enantioselectivities.
ChemInform Abstract: Palladium‐Catalyzed anti‐Markovnikov Hydroalkylation of Homoallylic Alcohols Bearing β‐Fluorines.
Authors: Lin Xiaowei , Qing Feng‐Ling 
Published: January 2014

AbstractOptimized reaction conditions allow the regioselective hydroalkylation of homoallylic alcohols, ethers, and amines with alkylzinc reagents to give the corresponding anti‐Markovnikov products.
ChemInform Abstract: Gold‐Catalyzed Intramolecular Oxidation of Terminal Alkynes: Simple and Efficient Synthesis of α‐Mesyloxy Ketones.
Authors: Xie Longyong , Liang Zhiwu , Yan Dong , He Weimin , Xiang Jiannan 
Published: January 2014

AbstractThe title reaction is proposed to proceed via α‐oxo gold carbene intermolecular O—H insertion.
ChemInform Abstract: Direct Conversion of N‐Alkoxyamides to Carboxylic Esters Through Tandem NBS‐Mediated Oxidative Homocoupling and Thermal Denitrogenation.
Authors: Zhang Ningning , Yang Rui , Zhang‐Negrerie Daisy , Du Yunfei , Zhao Kang 
Published: January 2014

AbstractThis method is suitable for the synthesis of sterically hindered carboxylic esters.
ChemInform Abstract: Cinchona‐Based Squaramide‐Catalyzed Cascade Aza‐Michael—Michael Addition: Enantioselective Construction of Functionalized Spirooxindole Tetrahydroquinolines.
Authors: Yang Wen , Du Da‐Ming 
Published: January 2014

AbstractTitle compounds [(III), (V) and (VII)] are efficiently synthesized with excellent diastereoselectivities (<25:1 d.r.) and high enantioselectivities using a chiral bifunctional tertiary amine‐squaramide catalyst.
ChemInform Abstract: Palladium(II)‐Catalyzed Synthesis of 2H,3′H‐Spiro[benzofuran‐3,2′‐naphthoquinones].
Authors: Claes Pieter , Jacobs Jan , Kesteleyn Bart , Nguyen Van Tuyen , De Kimpe Norbert 
Published: January 2014

AbstractNovel spiroheterocycles are prepared by an unprecedented Pd‐catalyzed spirocyclization.
ChemInform Abstract: Oxazolidine Sulfur Ylides Derived from Phenylglycinol for the Specific and Highly Diastereoselective Synthesis of Aryl and Alkyl trans‐Epoxyamides.
Authors: Gordillo Paola G. , Aparicio David M. , Flores Marcos , Mendoza Angel , Orea Laura , Juarez Jorge R. , Huelgas Gabriela , Gnecco Dino , Teran Joel L. 
Published: January 2014

AbstractCoupling of chiral sulfur ylides of type (VII) with aldehydes provides an efficient and highly diastereoselective approach to aryl and alkyl trans‐epoxyamides.
ChemInform Abstract: Novel Synthesis of 3‐Aryl‐4‐hydroxybenzofurans via Four‐Component Reaction from Substituted Nitrostyrenes, Aromatic Aldehydes, Cyclohexan‐1,3‐diones, and Ammonium Acetate.
Authors: Li Yan , Liu Hui , Sun Liang , Liu Juanjuan , Xue Zhiheng , Yao Juan , Wang Cunde 
Published: January 2014

AbstractA four‐component synthesis of functionalized 4‐hydroxybenzofurans is developed using nitrostyrenes, aromatic aldehydes, cyclohexane‐1,3‐diones and ammonium acetate as the reactants.
ChemInform Abstract: A Direct and General Method for the Reductive Alkylation of Tertiary Lactams/Amides: Application to the Step Economical Synthesis of Alkaloid (‐)‐Morusimic Acid D.
Authors: Xiao Kai‐Jiong , Wang Yu , Huang Ying‐Hong , Wang Xiao‐Gang , Huang Pei Qiang 
Published: January 2014

AbstractA full account on previously published studies as well as their application to an improved synthesis of title compound (IX) is presented.
ChemInform Abstract: Palladium Catalyzed Cyclizations of Oxime Esters with 1,2‐Disubstituted Alkenes: Synthesis of Dihydropyrroles.
Authors: Race Nicholas J. , Bower John F. 
Published: January 2014

AbstractThe Pd‐catalyzed cyclization of pentafluorobenzoyl oximes is studied, resulting in the formation of vinyl substituted dihydropyrroles.
ChemInform Abstract: Conversion of Cyclic Ketones to 2,3‐Fused Pyrroles and Substituted Indoles.
Authors: Alford Joshua S. , Spangler Jillian E. , Davies Huw M. L. 
Published: January 2014

AbstractThe new synthesis of 2,3‐fused pyrroles from alkenyl‐1‐sulfonyltriazoles is achieved by a rhodium‐catalyzed 4π‐electrocyclization.
ChemInform Abstract: Chiral Phosphoric Acid‐Catalyzed Oxidative Kinetic Resolution of Indolines Based on Transfer Hydrogenation to Imines.
Authors: Saito Kodai , Shibata Yukihiro , Yamanaka Masahiro , Akiyama Takahiko 
Published: January 2014

AbstractThis new method proceeding via hydrogen transfer to imines by means of a chiral phosphoric acid catalyst is applicable to both 2‐aryl and 2‐alkyl substituted indolines.
ChemInform Abstract: Csp2—N Bond Formation via Ligand‐Free Pd‐Catalyzed Oxidative Coupling Reaction of N‐Tosylhydrazones and Indole Derivatives.
Authors: Roche Maxime , Frison Gilles , Brion Jean‐Daniel , Provot Olivier , Hamze Abdallah , Alami Mouad 
Published: January 2014

AbstractThe new method for the synthesis of substituted N‐vinylazoles shows a broad functional group tolerance.
ChemInform Abstract: Direct Olefination at the C‐4 Position of Tryptophan via C—H Activation: Application to Biomimetic Synthesis of Clavicipitic Acid.
Authors: Liu Qiang , Li Qingjiang , Ma Yongfan , Jia Yanxing 
Published: January 2014

AbstractThe reaction proceeds under mild conditions with various substituted olefins to give the corresponding 4‐substituted tryptophans.
ChemInform Abstract: Palladium‐Catalyzed Intramolecular Cyclization of 2‐Iodobenzamides: An Efficient Synthesis of 3‐Acyl Isoindolin‐1‐ones and 3‐Hydroxy‐3‐acylisoindolin‐1‐ones.
Authors: Chen Wanli , Jin Lina , Zhu Yinghong , Cao Xiaoji , Zheng Lebin , Mo Weimin 
Published: January 2014

AbstractAn efficient Pd‐catalyzed cyclization of ortho‐iodobenzamides (I) is developed to give 3‐acylated isoindolin‐2‐ones (II) in moderate to good yields.
ChemInform Abstract: Gold and BINOL‐Phosphoric Acid Catalyzed Enantioselective Hydroamination/N‐Sulfonyliminium Cyclization Cascade.
Authors: Gregory Alex W. , Jakubec Pavol , Turner Paul , Dixon Darren J. 
Published: January 2014

AbstractAn initial 5‐exo‐dig hydroamination followed by phosphoric acid catalyzed cyclization process provide access to complex sulfonamide scaffolds (II) in good yield and high enantiocontrol.
ChemInform Abstract: A Tandem [3 + 2] Cycloaddition—Elimination Cascade Reaction to Generate Pyrrolo‐[3,4‐c]pyrrole‐1,3‐diones.
Authors: Martinez‐Ariza Guillermo , Dietrich Justin , De Moliner Fabio , Hulme Christopher 
Published: January 2014

AbstractA novel one‐pot 1,3‐dipolar cycloaddition‐elimination sequence allows the synthesis of the title compounds (III) from readily available pyrrole‐2,5‐diones and oxazolin‐2‐ones.
ChemInform Abstract: Facile Synthesis of 2‐Arylbenzimidazoles by Nano‐CuY Zeolite as an Efficient and Eco‐Friendly Nanocatalyst.
Authors: Kalhor Mehdi , Khodaparast Nooshin , Zendehdel Mojgan 
Published: January 2014

AbstractThe title compounds are obtained by an one‐pot condensation reaction of o‐phenylenediamine and various aromatic aldehydes.
ChemInform Abstract: Iodine(III)‐Mediated [3 + 2] Cyclization for One‐Pot Synthesis of Benzo[d]isoxazole‐4,7‐diols in Aqueous Medium.
Authors: Hou Yingwei , Lu Shichao , Liu Gang 
Published: January 2014

AbstractThe preparation of the title compounds proceeds via in situ generation of benzoquinones and nitrile oxides.
ChemInform Abstract: Synthesis of Chromeno[2,3‐d]imidazol‐9(1H)‐ones via Tandem Reactions of 3‐Iodochromones with Amidines Involving Copper‐Catalyzed C—H Functionalization and C—O Bond Formation.
Authors: Sheng Jia , Chao Bo , Chen Hong , Hu Youhong 
Published: January 2014

AbstractThe title synthesis involves the initial formation of imidazolyl substituted acyl phenols which undergo a copper‐catalyzed C—H‐activation/C—O bond formation process.
ChemInform Abstract: Sequential Oxidation—Prins Reaction Processes Induced by the Same Iron Salt: Direct Access to 2‐Aryl‐4‐chloro‐tetrahydropyrans from Benzyl Alcohols.
Authors: Fache Fabienne , Muselli Mickael , Piva Olivier 
Published: January 2014

AbstractIron nitrate supported on bentonite K10 is used to oxidize benzylic alcohols to the corresponding aldehydes.
ChemInform Abstract: ortho‐(Dimesitylboryl)phenylphosphines: Positive Boryl Effect in the Palladium‐Catalyzed Suzuki—Miyaura Coupling of 2‐Chloropyridines.
Authors: Malacea Raluca , Chahdoura Faouzi , Devillard Marc , Saffon Nathalie , Gomez Montserrat , Bourissou Didier 
Published: January 2014

AbstractThe presence of ortho‐dimesitylboryl moiety in the catalyst is crucial to enhance the catalytic performance.
ChemInform Abstract: The Oxidation of Pyridines Catalyzed by Surfactant‐Encapsulated Polyoxometalate [(C18H37)2(CH3)2N] 8[HBW11O39] with the Temperature‐Responsive Property of Solubility.
Authors: Zhao Wei , Yang Chunxia , Ding Yong , Ma Baochun 
Published: January 2014

AbstractThe green and efficient catalytic system can be recovered and reused several times.
ChemInform Abstract: meso‐Pyridyl BODIPYs with Tunable Chemical, Optical and Electrochemical Properties.
Authors: Bartelmess Juergen , Weare Walter W. , Latortue Narah , Duong Christina , Jones Daniel S. 
Published: January 2014

AbstractThe title compounds (III) can be applied as fluorescent pH sensors in a pH range from ca. 1 to 4.
ChemInform Abstract: Silver Triflate‐Palladium Chloride Cooperative Catalysis in a Tandem Reaction for the Synthesis of H‐Pyrazolo[5,1‐a]isoquinolines.
Authors: Xiao Qing , Sheng Jie , Ding Qiuping , Wu Jie 
Published: January 2014

AbstractA wide range of target compounds is prepared in good yields.
ChemInform Abstract: An Approach to the Synthesis of Tetrahydroisoquinoline Alkaloids by Alkene Hydroamination: Synthesis of Coralydine.
Authors: Pouilhes Annie , Baltaze Jean‐Pierre , Kouklovsky Cyrille 
Published: January 2014

AbstractIntramolecular hydroamination of compound (I) offers an efficient access to coralydine (IV) and its epimer O‐methylcorytenchirine (V).
ChemInform Abstract: Regioselective Synthesis of 6‐Substituted‐2‐amino‐5‐bromo‐4(3H)‐pyrimidinones and Evaluation of Their Antiviral Activity.
Authors: Singh Kamaljit , Singh Kawaljit , Balzarini Jan 
Published: January 2014

AbstractThe synthesis of the title compounds uses a highly regioselective lithiation‐substitution protocol employing different types of electrophiles.
ChemInform Abstract: Synthesis and Properties of Imidazolo‐Fused Benzotriazinyl Radicals.
Authors: Berezin Andrey A. , Constantinides Christos P. , Mirallai Styliana I. , Manoli Maria , Cao Levy L. , Rawson Jeremy M. , Koutentis Panayiotis A. 
Published: January 2014

AbstractA two‐step synthesis of title radicals (IV) is elaborated using a base‐promoted reaction of benzotriazinone (I) with benzamidines (II) followed by cyclization of resulting benzimidamides (III) in acetic acid.
ChemInform Abstract: Facile and Efficient Lewis Acid Catalyzed Synthesis of an Asymmetric Tetrazine Useful for Bio‐Orthogonal Click Chemistry Applications.
Authors: Alge Daniel L. , Donohue Dillon F. , Anseth Kristi S. 
Published: January 2014

AbstractThe reported simple two‐step method for the synthesis of tetrazine (V) is a significant improvement over previously reported methods.
ChemInform Abstract: Cu‐Catalyzed Asymmetric Borylative Cyclization of Cyclohexadienone‐Containing 1,6‐Enynes.
Authors: Liu Ping , Fukui Yuki , Tian Ping , He Zhi‐Tao , Sun Cai‐Yun , Wu Nuo‐Yi , Lin Guo‐Qiang 
Published: January 2014

AbstractFirst time, the title reaction is achieved through a tandem process involving selective β‐borylation of propargylic ether and subsequent conjugate addition to cyclohexadienone.
ChemInform Abstract: Redox‐Neutral α‐C—H Bond Functionalization of Secondary Amines with Concurrent C—P Bond Formation/N‐Alkylation.
Authors: Das Deepankar , Seidel Daniel 
Published: January 2014

AbstractRedox‐neutral formation of C—P bonds in the α‐position of amines is achieved via a process that features a combination of an oxidative α‐C—H bond functionalization and a reductive N‐alkylation.
ChemInform Abstract: Phosphoryl‐Related Directing Groups in Rhodium(III) Catalysis: A General Strategy to Diverse P‐Containing Frameworks.
Authors: Zhao Dongbing , Nimphius Corinna , Lindale Matthew , Glorius Frank 
Published: January 2014

AbstractArylphosphonates and phosphonamides are functionalized at the ortho position via Rh‐catalyzed oxidative C—H activation and subsequent coupling with alkenes, arenes, and alkynes.
ChemInform Abstract: Unprecedented Synthesis of Alkynylphosphine‐Boranes Through Room‐Temperature Oxidative Alkynylation.
Authors: Jouvin Kevin , Veillard Romain , Theunissen Cedric , Alayrac Carole , Gaumont Annie‐Claude , Evano Gwilherm 
Published: January 2014

AbstractOxidative alkynylation of phosphine‐boranes with alkynylcopper reagents allows a practical synthesis of alkynylphosphine‐boranes.
ChemInform Abstract: One‐Pot Synthesis of Ferrocenyl Ketones Containing Biaryls and 6‐Aryl‐2‐ferrocenylquinolines via Ir/Pd‐Cocatalyzed α‐Alkylation/Suzuki Reaction.
Authors: Xu Chen , Hao Xin‐Qi , Xiao Zhi‐Qiang , Wang Zhi‐Qiang , Yuan Xiao‐Er , Fu Wei‐Jun , Ji Bao‐Ming , Song Mao‐Ping 
Published: January 2014

AbstractThese efficient methods use simple reaction conditions and tolerate a variety of functional groups.
ChemInform Abstract: Total Synthesis of Cyanthiwigins A, C, G, and H.
Authors: Wang Cheng , Wang Dan , Gao Shuanhu 
Published: January 2014

AbstractThe core structure for the first total synthesis of cyanthiwigins A, C, H and G is obtained by formal [4 + 2] cycloaddition, stereospecific 1,4‐addition, alkylation, and ring‐closing metathesis.
ChemInform Abstract: Synthesis of 2‐Nitroglycals from Glycals Using the Tetrabutylammonium Nitrate—Trifluoroacetic Anhydride—Triethylamine Reagent System and Base‐Catalyzed Ferrier Rearrangement of Acetylated 2‐Nitroglycals.
Authors: Dharuman Suresh , Gupta Preeti , Kancharla Pavan K. , Vankar Yashwant D. 
Published: January 2014

AbstractThe new reagent system is used for the synthesis of 2‐nitroglycals from various protected glycals and can also be applied to non‐carbohydrate olefins.
ChemInform Abstract: Synthesis and Biophysical Properties of Constrained D‐Altritol Nucleic Acids (cANA).
Authors: Migawa Michael T. , Prakash Thazha P. , Vasquez Guillermo , Seth Punit P. , Swayze Eric E. 
Published: January 2014

AbstractConstrained altritol nucleotide derivatives (I) are incorporated into antisense oligonucleotides (ASO) in order to study how conformationally restricting the D‐altritol backbone‐containing ASO will affect their ability to form duplexes with RNA.
ChemInform Abstract: Total Synthesis of Geralcin A, a Representative of a New Family of Hydrazine‐Containing Natural Product.
Authors: Le Goff Geraldine , Roulland Emmanuel , Ouazzani Jamal 
Published: January 2014

AbstractThe first total synthesis of geralcin A (I), a naturally occurring α,β‐unsaturated γ‐lactonohydrazide produced by Streptomyces sp.
ChemInform Abstract: Synthesis of 4‐Benzyl‐3‐phenylbutenolide Natural Products.
Authors: Parker Anna N. , Lock Matthew J. , Hutchison John M. 
Published: January 2014

AbstractThe first total synthesis of eutypoid A (Ia) and new syntheses of gymnoascolide A (Ib) and of racemic microperfuranone (II) are reported.
ChemInform Abstract: Structures of Spiroindicumides A and B, Unprecedented Carbon Skeletal Spirolactones, and Determination of the Absolute Configuration by Vibrational Circular Dichroism Exciton Approach.
Authors: Asai Teigo , Taniguchi Tohru , Yamamoto Takashi , Monde Kenji , Oshima Yoshiteru 
Published: January 2014

AbstractSpiroindicumides A (Ia) and B (Ib), novel spirolactone polyketides, are isolated from a filamentous fungus, Chaetomium indicum, cultivated in the presence of a histone deacetylase inhibitor.
ChemInform Abstract: Science‐Intensive Utilization of Environmentally Harmful Polychlorocarbons. Synthesis of Biologically Active Cyclopentanoids from Hexachlorocyclopentadiene
Authors: Tolstikov G. A. , Ismailov S. A. , Gimalova F. A. , Ivanova N. A. , Miftakhov M. S. 
Published: January 2014

AbstractReview: 26 refs.
(−)‐R‐Mevalonolactone Studied by ROA and SERS Spectroscopy
Authors: Chruszcz‐Lipska Katarzyna , Jaworska Aleksandra , Szczurek Ewelina , Baranska Malgorzata 
Published: January 2014

ABSTRACTHere we present for the first time the experimental and theoretical (DFT/B3LYP/6‐311++G**) Raman optical activity (ROA) spectra of (−)‐R‐mevalonic acid as the δ‐lactone form in neat liquid and in the aqueous solution. Quantum chemical calculations show the conformational diversity of (−)‐R‐mevalonolactone originated from small energy differences between the various conformation of the six‐membered ring and the arrangement of the hydroxyl group. According to calculations, the investigated compound takes predominantly the chair conformation with the hydroxyl group in axial position, but the contribution of the other chair and boat conformers in the equilibrium at room temperature is not negligible. Additionally, we present normal Raman and the surface enhanced Raman (SERS) spectra of (−)‐R‐mevalonolactone adsorbed on the colloidal silver. Chirality 26:453–461, 2014. © 2014 Wiley Periodicals, Inc.
Uncovering nativity disparities in cancer patterns: Multiple imputation strategy to handle missing nativity data in the Surveillance, Epidemiology, and End Results data file
Authors: Montealegre Jane R. , Zhou Renke , Amirian E. Susan , Scheurer Michael E. 
Published: January 2014

BACKGROUNDAlthough birthplace data are routinely collected in the participating Surveillance, Epidemiology, and End Results (SEER) registries, such data are missing in a nonrandom manner for a large percentage of cases. This hinders analysis of nativity‐related cancer disparities. In the current study, the authors evaluated multiple imputation of nativity status among Hispanic patients diagnosed with cervical, prostate, and colorectal cancer and demonstrated the effect of multiple imputation on apparent nativity disparities in survival.METHODSMultiple imputation by logistic regression was used to generate nativity values (US‐born vs foreign‐born) using a priori‐defined variables. The accuracy of the method was evaluated among a subset of cases. Kaplan‐Meier curves were used to illustrate the effect of imputation by comparing survival among US‐born and foreign‐born Hispanics, with and without imputation of nativity.RESULTSBirthplace was missing for 31%, 49%, and 39%, respectively, of cases of cervical, prostate, and colorectal cancer. The sensitivity of the imputation strategy for detecting foreign‐born status was ≥ 90% and the specificity was ≥ 86%. The agreement between the true and imputed values was ≥ 0.80 and the misclassification error was ≤ 10%. Kaplan‐Meier survival curves indicated different associations between nativity and survival when nativity was imputed versus when cases with missing birthplace were omitted from the analysis.CONCLUSIONSMultiple imputation using variables available in the SEER data file can be used to accurately detect foreign‐born status. This simple strategy may help researchers to disaggregate analyses by nativity and uncover important nativity disparities in regard to cancer diagnosis, treatment, and survival. Cancer 2014;120:1203–1211. © 2014 American Cancer Society.
Hydrogen‐Bond‐Assisted Activation of Allylic Alcohols for Palladium‐Catalyzed Coupling Reactions
Authors: Gumrukcu Yasemin , de Bruin Bas , Reek Joost N. H. 
Published: January 2014

AbstractWe report direct activation of allylic alcohols using a hydrogen‐bond‐assisted palladium catalyst and use this for alkylation and amination reactions. The novel catalyst comprises a palladium complex based on a functionalized monodentate phosphoramidite ligand in combination with urea additives and affords linear alkylated and aminated allylic products selectively. Detailed kinetic analysis show that oxidative addition of the allyl alcohol is the rate‐determining step, which is facilitated by hydrogen bonds between the alcohol, the ligand functional group, and the additional urea additive.