bluuebunny/crossref_metadata_2025_split huggingface dataset:
FORMS OF ECONOMIC PROXIMITY AND THEIR IMPACT ON INNOVATION PERFORMANCE: A STUDY OF MULTIDISCIPLINARY COMMERCIAL ORGANISATIONS IN INDUSTRY
Authors: Trachuk A. V. , Kolobov A. V. 
Published: July 2024

This article analyses the influence of different types of economic proximity (geographical, organisational, technological and social) of business units of multidisciplinary organisations on the effectiveness of their innovative activities. The conducted research is based on a survey of a sample of 83 holdings belonging to 27 MCOs (a total of 189 respondents). The analysis confirmed that most of the companies surveyed associate increased efficiency of innovation activities with organisational and technological proximity, while geographical and social proximity are significantly underestimated by respondents. It was also possible to identify separate profiles of different types of economic proximity of the business units in the sample. Thus, the net profit from the sale of new products is more influenced by technological and social proximity, the introduction of new products to the market is influenced by technological and geographical proximity, and the growth in the number of patents registered is influenced by organisational, technological and social proximity.Based on econometric estimates, our results suggest that while all types of proximity have a positive effect on the introduction of new products to the market, only organisational and technological proximity have a direct effect on net profits from the sale of new products.
DEMAND FOR JEWELLERY: THE MAIN DRIVERS
Authors: Umgaeva O. V. 
Published: July 2024

Jewellery made of precious stones and metals is a luxury item, referring to goods with excessive consumer properties. At the same time, the sphere of turnover of precious metals, precious stones (PMPS) and products made from them is of strategic importance for the formation and development of the state economy. Businesses operating in this sphere are subject to compulsory registration in a special state register. The government is interested in supporting the jewellery industry and increasing its turnover, which is directly dependent on the population’s demand for PMPS products.Popular demand, in turn, depends on many factors that have their own specificities in relation to the area under study. An assessment of the factors based on expert opinion, conducted by the author with interviews of a group of consumers, the study of scientific research materials and journalistic articles from various Internet resources, indicates the acceptable superiority of offers of jewellery made of precious stones and metals, focused on the potential increase in the possibilities of sunlight.The conclusions presented in the paper on the factors influencing demand are recommended for use in the development of business development strategies and may be useful in making decisions on state regulation of the sale of jewellery made from PMPS.
Comparative study of tear flim abnormalities and dry eye conditions in ocular surface following phacoemulsification and small incision cataract surgery [SICS] A hospital based prospective study
Authors: Kannappan Shamili , Jeyaprakash  , Ezhilvendhan  , Nanda Jashaswini , Devi Sozhama 
Published: July 2024

To study ocular surface and tear flim abnormalities in patients undergoing [PHACO] and [SICS]. [DED] is a disease of either tears or the ocular surface which leads to visual disturbance. SICS resulting in corneal hyposensitivity and reduction in reflex secretion and wound healing. PHACO is a contemporary cataract surgery in which the eyes internal lens is emulsified and aspirated from the eye using an ultrasonic handpiece.A Hospital based prospective study involved 100 patients aged 40-65 years.100 patients were subdivided into 2 groups, 50 members in each group. The observation of TBUT before surgery and after 1,3,6 months post-surgery were carried out in both group of patients.In this study 100 patients were subdivided into 2 groups, 50 members in each group as follows Group 1-50 patients scheduled for SICS with PCIOL implantation, Group 2-50 patients scheduled for PHACO with PCIOL implantation. Preoperatively the mean Schrimer value was 13.70 and 13.40 in patients underwent SICS and PHACO respectively. At postoperative 1 week, 89.1% of the group had grade 2 dry eye compared to 92.9% in the SICS group [p 0.0001].Individuals with SICS had a higher prevalence and severity of dry eyes than those with PHACO.
Clinical study on association of diabetic retinopathy severity with HbA1c level
Authors: Sharma Pankaj Kumar , Kumar Kavita , Dubey Aditi , Kushwaha Nitin , Maravi Pooja 
Published: July 2024

Patients with diabetic retinopathy (DR) have a greater risk of blindness compared to those without diabetes. HbA1c is a valuable indicator used to assess the long-term management of diabetes mellitus. Hence, the main objective of this study was to explore the relationship between HbA1c levels and the severity of diabetic retinopathy.This one-year prospective observational clinical study was conducted at the Department of Ophthalmology and Diabetic Clinic, Gandhi Medical College, Bhopal, involving 100 diabetic patients. Detailed medical histories related to their diabetes were recorded. The diabetic retinopathy status of each patient was assessed through a comprehensive ophthalmologic examination and classified according to the early treatment diabetic retinopathy study (ETDRS) system. Clinical data of the patients, including HbA1c levels, were gathered during the study period.Among the 100 patients, 29% were females, while the remaining 71% were males. A notable finding emerged, revealing a significant link between the severity of diabetic retinopathy and HbA1c levels. Additionally, the duration of diabetes and lipid levels also demonstrated a significant association with the severity of retinopathy (P value &#60; 0.05). However, the age and gender of the patients did not exhibit a significant correlation when compared across different grades of diabetic retinopathy (P value &#62; 0.05). ROC analysis revealed that an HbA1c cutoff of 7.6% was the most effective in detecting both the presence of any diabetic retinopathy and its grades. A strong statistical relationship was found between HbA1c levels and the severity of diabetic retinopathy. Patients with higher HbA1c levels, indicating poorer blood sugar control, showed more severe grades of diabetic retinopathy. HbA1c levels emerged as a reliable predictor for both the presence and severity of diabetic retinopathy.
Clinical profile and associations of binocular vision dysfunction at a vision therapy clinic of a tertiary eye institute in India
Authors: Yadav Roshan Kumar , Sah Sunil Kumar , Chauhan Himani , Kumar Prashant , Ali Akram , Singh Ruby 
Published: July 2024

Review the incidence of binocular dysfunctions, clinical features, their association with binocular vision disorders and refractive status at a vision therapy clinic of a tertiary eye institute in India. In this retrospective study, the clinical record of all the patients of binocular dysfunction was obtain from Electronic medical record (EMR). We reviewed the record of 527 symptomatic patients with binocular vision dysfunction related problems who were referred between July 2022 to June 2023, to binocular vision therapy clinic. Out of which 393 patients (74.57%) who had accommodative dysfunction were included in the study. Patients with any ocular surgery, manifest strabismus, amblyopia, anisometropia (more than 2.00 dioptres), ocular pathology, neurological disorders, were not included in the review. Prepresbyopic patient also excluded from this study. All clinical assessments were done by one of the two experienced optometrists. Of the 527 symptomatic patients examined, 74% (393 subjects) showed binocular dysfunction. Among the 393 binocular dysfunction patients, most of them diagnose with convergence insufficiency (18.82%), convergence insufficiency with accommodative insufficiency (26.97%), convergence insufficiency with accommodative infacility (23.40%), convergence insufficiency with accommodative excess (19.24%), poor PFV (4.58%), and convergence excess (6.36%).: In conclusion, we have evaluated the binocular vision dysfunctions of a non-presbyobic population. Out of 527 symptomatic patients examined, 74% (393 patients) showed had binocular dysfunctions. Incident CI was more than CE. This study will provide the prevalence data of binocular vision dysfunction. The study will also provide insight into the differences in binocular vision parameters. A diagnosis of binocular dysfunction depends not only on a few clinical findings of some accommodative and binocular investigations but on a whole battery of tests, in order to produce diagnosis of the type of dysfunction of the patient. For this reason optometrists should systematically complement their routine examination with a whole battery of accommodative and binocular tests that would help to avoid the non-detection of these anomalies in daily optometric practice.
Kapłan, powstaniec, emigrant – ks. Władysław Godlewski (1804-1867)
Authors: Kuzicki Jerzy 
Published: July 2024

Artykuł stanowi próbę monograficznego ujęcia postaci ks. Władysława Godlewskiego. Z osobą tego dziewiętnastowiecznego kapłana autor zetknął się podczas pracy nad monografią poświęconą duchowieństwu Wielkiej Emigracji. Prozopograficzny charakter tego opracowania nie pozwolił na ujęcie wszystkich szczegółów biograficznych życia tego duchownego. Pomimo kilku opracowań w słownikach biograficznych koleje życia tego kapłana zawierają pewne nieścisłości, które wymagały uzupełnień. W artykule przedstawiono młodość Godlewskiego, jego udział w powstaniu listopadowym, edukację, pobyt na emigracji w Anglii, w Belgii, we Włoszech (Rzym) i we Francji. Najwięcej miejsca poświęcono działalności duszpasterskiej ks. Godlewskigo, w tym zwłaszcza kaznodziejstwu. Początkowo ks. Godlewski był związany ze zmartwychwstańcami, ale wkrótce odszedł z tego zgromadzenia. Prowadził działalność duszpasterską w kilku ośrodkach Wielkiej Emigracji, najwięcej w Misji Polskiej w Paryżu.
Artykuł powstał na podstawie opracowań, prasy emigracyjnej oraz zachowanej korespondencji i tekstów homilii z archiwum zmartwychwstańców w Rzymie, Biblioteki Polskiej w Paryżu i Biblioteki Czartoryskich w Krakowie.
Elżbietanki w diecezji warmińskiej po II wojnie światowej w świetle zachowanej dokumentacji w Archiwum Akt Nowych Archidiecezji Warmińskiej w Olsztynie
Authors: Kopiczko Andrzej 
Published: July 2024

W artykule przedstawiono dzieje Zgromadzenia Sióstr św. Elżbiety w diecezji warmińskiej po 1945 r. Na tym terenie podjęło ono działalność już w 1864 r. i w kolejnych dziesięcioleciach utworzyło 24 domy. Jednak po II wojnie światowej, wskutek strat osobowych i zmian granic diecezji, elżbietanki pracowały tylko w dziewięciu placówkach. Już na początku lat pięćdziesiątych XX wieku – z powodu represji – opuściły Kwidzyn, natomiast zaraz po wojnie utworzyły dom w Olsztynie. Ten też nie przetrwał długo, ponieważ w 1948 r. w miejsce elżbietanek przybyły siostry Rodziny Maryi. Poza Kwidzynem placówki przedwojenne przetrwały w Bartoszycach, Biesowie, Orzechowie, Ostródzie, Postolinie i Straszewie. Natomiast po 1945 r., poza Olsztynem, w 1951 r. utworzono jeszcze dom w Nowym Kawkowie. Elżbietanki w swoich placówkach koncentrowały się na ambulatoryjnej pielęgnacji chorych, dziełach miłosierdzia w ramach Caritas, opiece nad kościołami i katechizacji. Jednak po 1970 r. zamykały swoje domy, a w momencie podziału diecezji warmińskiej w 1992 r. już na jej terenie nie było żadnego; ostatni został zlikwidowany w 1989 r. w Nowym Kawkowie.
SOSIALISASI PRODUK PANGAN CRACKERS “CANGTUK” BERBAHAN KACANG HIJAU DAN DAUN KATUK SEBAGAI PANGAN BERGIZI PENCEGAHAN STUNTING PADA BALITA DI DAERAH PONCOGATI
Authors: Fauziah Riska Rian , Aini Redita Shafiva , Kamalia Lufiy , Andansari Dita , Nurhaliza Nadia Siti , Adilia Rika 
Published: July 2024

Stunting (balita pendek) merupakan gangguan tumbuh kembang yang sering dialami anak akibat gizi buruk, infeksi berulang, dan stimulasi psikososial yang tidak memadai. Kabupaten Bondowoso merupakan salah satu daerah yang terdampak khususnya di Desa Poncogati. Pencegahan stunting salah satunya dapat dilakukan dengan pemberian pangan bergizi. Pengembangan pangan bergizi yang dilakukan berupa crackers berbahan dasar kacang hijau dan daun katuk yang selanjutnya disebut crackers Cangtuk ditujukan untuk upaya pencegahan dan mengurangi kasus stunting yang terjadi di desa Poncogati. Kandungan gizi dari crackers Cangtuk yang terdiri dari protein 9,41%; lemak 26,61%, karbohidrat 49,36% serta mineral sebesar 2,06% diharapkan mampu mengurangi dan mencegah kasus stunting di Desa Poncogati. Kegiatan pengabdian dilakukan dengan memberikan sosialisasi terkait stunting dan pencegahannya dilanjutkan dengan pengenalan produk crackers Cangtuk bagi balita dan ibu hamil sebagai upaya pencegahan stunting.
Ultrahigh thermal stability and piezoelectricity of lead-free piezoceramics through mimicking PZT’s MPB structure
Authors: Zhai Jiwei , xu lihui , Lin Jinfeng , yang yuxuan , zhao zhihao , Shi Xiaoming , Ge Guanglong , Qian Jin , Shi Cheng , li guohui , wang siming , zhang yang , Shen Bo , Fu Zhengqian , Huang Houbing , Wu Haijun 
Published: July 2024

Abstract

High-performance (K, Na)NbO3 (KNN) based piezoceramics is attractive as an alternative to Pb-based piezoceramics because of the growing concerns for environmental sustainability. Unfortunately, the serious contradiction between the high piezoelectricity generated by the construction of polymorphic phase boundary (PPB) and their uniquely poor temperature stability is a huge obstacle to the applications for KNN-based ceramics. In this study, the 0.94(Na0.56K0.44)NbO3-0.03Bi0.5Na0.5ZrO3-0.03(Bi0.5K0.5)HfO3 textured ceramics possess a novel phase boundary similar to MPB in PZT via the synergistic optimization of diffusion phase boundary and crystal orientation. As a result, the prominent comprehensive piezoelectricity with a giant d33 ∼ 550 ± 30 pC/N and ultrahigh temperature stability (d33 change rate less than 1.2% within 25 to 150 ℃, and less than 10% within 25-250 °C) were obtained, representing a significant breakthrough in lead-free piezoelectric ceramics. This study demonstrates a strategy of constructing a new-type phase boundary with MPB feature to solve the issue of temperature instability in high-performance KNN-based ceramics, which greatly accelerates the development and application of lead-free piezoelectric ceramics.
Prenatal stress and gestational epigenetic age: No evidence of associations based on a large prospective multi-cohort study
Authors: Murgatroyd Chris , Salontaji Kristina , Smajlagic Dinka , Page Christian , Sanders Faye , Jugessur Astanand , Lyle Robert , Tsotsi Stella , Haftorn Kristine , Felix Janine , Walton Esther , Tiemeier Henning , Cecil Charlotte , Bekkhus Mona 
Published: July 2024

Abstract

Psychological stress during pregnancy is known to have a range of long-lasting negative consequences on the development and health of offspring. Here, we tested whether a measure of prenatal early-life stress was associated with a biomarker of physiological development at birth, namely epigenetic gestational age, using foetal cord-blood DNA-methylation data. Longitudinal cohorts from the Netherlands (Generation R Study [Generation R], n = 1,396), the UK (British Avon Longitudinal Study of Parents and Children [ALSPAC], n = 642), and Norway (Mother, Father and Child Cohort Study [MoBa], n1 = 1,212 and n2 = 678) provided data on prenatal maternal stress and genome-wide DNA methylation from cord blood and were meta-analysed (pooled n = 3,928). Measures of epigenetic age acceleration were calculated using three different gestational epigenetic clocks: “Bohlin”, “EPIC overlap” and “Knight”. Prenatal stress exposure, examined as an overall cumulative score, was not significantly associated with epigenetically-estimated gestational age acceleration or deceleration in any of the clocks, based on the results of the pooled meta-analysis or those of the individual cohorts. No significant associations were identified with specific domains of prenatal stress exposure, including negative life events, contextual (socio-economic) stressors, parental risks (e.g., maternal psychopathology) and interpersonal risks (e.g., family conflict). Further, no significant associations were identified when analyses were stratified by sex. Overall, we find little support that prenatal psychosocial stress is associated with variation in epigenetic age at birth within the general paediatric population.
Astrocytic Bestrophin1 in the Anterior Cingulate Cortex Modulates the Formation and Persistence of Morphine Addiction Memory
Authors: Sun Linlin , Liu Zepeng , Li Yifan , Lin Xiaorui , Huo Yu , Guo Shengyang , Fan Xiang , Ye Xinzhi , Yao Yun , Liu Jiao , Wang Ning , Song Sen , Li Yijing 
Published: July 2024

Abstract

Emerging evidence indicates that astrocytes play a vital role in both the establishment and preservation of memories. However, their specific contribution to addiction-related memory remains largely unresolved. In this study, we observed alterations in Ca2+ dynamics within astrocytes of the anterior cingulate cortex (ACC) during the acquisition, recent retrieval, and remote retrieval phases of morphine-conditioned place preference (CPP). Selective activation of Gi signaling in ACC astrocytes during the acquisition phase, rather than during retrieval or transfer phases, led to a significant and prolonged increase in the morphine CPP score. In contrast, activation of Gq signaling led to a reduction in the CPP score, which was both diminished and shortened. Additionally, we noted a significant increase in astrocytic Bestrophin 1 (BEST1) expression in the ACC during the morphine CPP acquisition phase. Selective knockdown of BEST1 from ACC astrocytes elevated astrocytic Ca2+ dynamics, expanded astrocytic coverage, alleviated astrocytic glutamate release, and altered the density of synapses between the dorsal hippocampus (dCA1) and ACC within the astrocytic microdomains. Mice lacking astrocytic BEST1 displayed impaired activity in ACCdCA1 neurons and decreased CPP scores. These findings suggest that ACC astrocytes modulate the connectivity between dCA1 and ACC neurons, possibly through extrasynaptic glutamate activity, thereby regulating the strength and persistence of morphine-associated memory.
Advanced Composite Triboelectric Nanogenerator from Bacterial Cellulose and MgAl-LDH Nanosheets: Synthesis, Performance, and Mechanistic insight
Authors: Mohsom Phitchayaphorn , Suktep Natdanai , Pongampai Satana , Pakawanit Phakkhananan , Chiu Te-Wei , Maluangnont Tosapol , Vittayakorn Naratip , Charoonsuk Thitirat 
Published: July 2024

Abstract

Rapid development of modern wearable-implantable medical devices has led to research on mechanical energy harvesting technologies, especially triboelectric nanogenerator (TENG) for being sustainable/flexible power supply or self-powered sensor. The most challenge part is searching advanced materials and designing them with excellent electrical performance while being flexible, lightweight, and non-toxic. Layered double hydroxides (LDH) have sparked research interest owing to the facile tunability of composition, morphology, and physicochemical properties. In this work, magnesium aluminum layer double hydroxide (MgAl-LDH) nanosheets were employed as a dielectric filler dispersed onto bacterial cellulose (BC) matrix, prior to the application as a friction layer in TENG. Phase identification, functional groups, and morphology of the nitrate-intercalated MgAl-LDH layered crystals have been investigated, including the nanosheets (NS) colloid exfoliated therefrom in formamide. Mechanistic insight with a detailed discussion of experimental results linked to scientific theory is deeply explained. The optimized BC/MgAl-LDH NS (1.5%v/v) film, simply prepared by casting, delivers the open-circuit voltage (VOC), short-circuit current (ISC), and maximum output power (Pmax) of 88.5 V, 87.7 µA and 1250 µW (138 µW/cm2), respectively. The composite serves not only as a nanogenerator driving 200 LEDs but also as a self-powering sensor detecting finger movements that might be useful for developing trigger finger monitoring in future.
Complete Blood Count Inflammatory Ratios in Attention Deficit Hyperactivity Disorder Children
Authors: Afify Mohamed Farouk , kamel asmaa khalf , Ali Marwa Waly Eldin 
Published: July 2024

Abstract

Background
Attention deficit hyperactivity disorder (ADHD) is considered the most common neuropsychiatric disorder in children. Many researchers have suggested that changes in pro-inflammatory and anti-inflammatory cytokines could play a role in the pathogenesis of ADHD. We aimed in this study to evaluate the relationships between the CBC inflammatory markers (NLR, MLR, PLR, and MPV) and the severity of attention deficit hyperactivity disorder symptoms in children. Method: This study was a cross-sectional case-control study carried out on 80 ADHD children and 40 apparently healthy children as the control group. A complete blood count was obtained (white blood cell (WBC), neutrophil count, lymphocyte count, monocyte count, eosinophil and basophil counts, platelets, and mean platelet volume (MPV). Based on these counts, the neutrophil lymphocyte ratio (NLR), platelet lymphocyte ratio (PLR), and monocyte lymphocytic ratio were calculated. Results: CBC inflammatory ratios (NLR, MLR, and PLR) were considerably higher among children with ADHD than in the control group; moreover, a significant positive correlation was observed between the CBC inflammatory ratios (neutrophil/lymphocyte, monocyte/lymphocyte) and ADHD symptoms severity assessed by Conner's parent rating scale scores (total ADHD score, hyperactivity, impulsivity, and inattention scores). Conclusions: The results of our study proved that inflammation plays a significant role in the intricate pathophysiology of ADHD and suggest that CBC inflammatory ratios can be used as an indicator for ADHD severity. This is easily obtainable and reliable in evaluating the role of inflammation in ADHD etiology.