bluuebunny/crossref_metadata_2025_split huggingface dataset:
A radiation quality correction factor kQ for well‐type ionization chambers for the measurement of the reference air kerma rate of 60Co HDR brachytherapy sources
Authors: Schüller Andreas , Meier Markus , Selbach Hans‐Joachim , Ankerhold Ulrike 
Published: June 2015

Purpose:The aim of this study was to investigate whether a chamber‐type‐specific radiation quality correction factor kQ can be determined in order to measure the reference air kerma rate of 60Co high‐dose‐rate (HDR) brachytherapy sources with acceptable uncertainty by means of a well‐type ionization chamber calibrated for 192Ir HDR sources.Methods:The calibration coefficients of 35 well‐type ionization chambers of two different chamber types for radiation fields of 60Co and 192Ir HDR brachytherapy sources were determined experimentally. A radiation quality correction factor kQ was determined as the ratio of the calibration coefficients for 60Co and 192Ir. The dependence on chamber‐to‐chamber variations, source‐to‐source variations, and source strength was investigated.Results:For the PTW Tx33004 (Nucletron source dosimetry system (SDS)) well‐type chamber, the type‐specific radiation quality correction factor kQ is 1.19. Note that this value is valid for chambers with the serial number, SN ≥ 315 (Nucletron SDS SN ≥ 548) onward only. For the Standard Imaging HDR 1000 Plus well‐type chambers, the type‐specific correction factor kQ is 1.05. Both kQ values are independent of the source strengths in the complete clinically relevant range. The relative expanded uncertainty (k = 2) of kQ is = 2.1% for both chamber types.Conclusions:The calibration coefficient of a well‐type chamber for radiation fields of 60Co HDR brachytherapy sources can be calculated from a given calibration coefficient for 192Ir radiation by using a chamber‐type‐specific radiation quality correction factor kQ. However, the uncertainty of a 60Co calibration coefficient calculated via kQ is at least twice as large as that for a direct calibration with a 60Co source.
A Quantitative Analysis on Semantic Relations of Data Blocks in Storage Systems
Authors: Chen Yunliang , Li Fangyuan , Du Bo , Fan Junqing , Deng Ze 
Published: June 2015

In a big data era, there are and will be more demands and higher requirements for data organization and management in the storage system. Previous studies on semantic relations of blocks have set an essential theoretical basis in storage systems. Revealing semantic relationship of blocks has great scientific values and indicates a promising prospect in the application. However, only qualitative description of block correlations has been obtained by traditional ways, and few researches have been done on unifying and quantizing the blocks semantic relationships. In this paper, an uniform design-aided gene expression programming (UGEP) method has been proposed to address this issue. After analyzing historical access streams, a quantitative description system on semantic relationship of blocks is established. The semantic relationship of blocks can also be used in prefetching in storage system, which means the next access block can be calculated by the prefetching model. Simulation tests in four real system traces indicate that compared with sequential prefetching and no prefetching model, the quantitative semantic relationships model based on UGEP can highly improve the performance of the storage system. The experimental results show that in Cello-92 cases, compared with no prefetching method and sequential prefetching method, prefetching based on UGEP can reduce average I/O response time by 23.7% and 17.9%, and hit ratio is also increased by 16% and 8% as well.
Using Your Fingers to Think: Enabling Subjective Routing with a Rubber Band Metaphor
Authors: Bennett Andrew , D'Orazio Matthew , Lueg Christopher 
Published: June 2015

There is a class of complex problems where solutions must satisfy multiple subjective criteria, while meeting specific quantifiable constraints. Route planning for leisurely travel is an example of a problem in this class. Constraints including total available time, transit times, and one's budget and subjective interests determine whether a potential solution is acceptable to a prospective traveler. In this paper we present a route planning (routing) interface that metaphorically leverages various elastic properties of a rubber band to allow for playful interaction with the relevant constraints. Each of these properties — attenuation, tension, and color — were integrated into an experimental system and then investigated in a series of task-based evaluations. Our research shows this playful interaction enables potential travelers to explore the solution space in order to find a route that meets, not only the easily quantifiable constraints, but also their own subjective preferences.
Genus Leptoiulus Verhoeff, 1894 new to the fauna of the Asian part of Russia, with description of a new species from the Altai and its comparison with the European Leptoiulus trilineatus (C.L. Koch, 1847) (Diplopoda, Julida, Julidae)
Authors: MIKHALJOVA ELENA V. , NEFEDIEV PAVEL S. , NEFEDIEVA JULIA S. , DYACHKOV YURI V. 
Published: June 2015

The diplopod genus Leptoiulus Verhoeff, 1894 is new to the fauna of the Asian part of Russia, due to the discovery of L. tigirek sp. nov. from the south-western part of the Altai Province, Siberia. A description of the new species and information on its habitats, numbers and locomotor activity as well as comparison with the European Leptoiulus trilineatus (C.L. Koch, 1847) are presented.
Cluster Analysis of Northern Hemisphere Wintertime 500-hPa Flow Regimes during 1920–2014*
Authors: Bao Ming , Wallace John M. 
Published: June 2015

Abstract
Clusters in the Northern Hemisphere wintertime, 10-day low-pass-filtered 500-hPa height field are identified using the method of self-organizing maps (SOMs). Results are based on 1) a 57-winter record of ERA and 2) a 93-winter record of the NOAA Twentieth-Century Reanalysis (20CR). The clusters derived from SOMs appear to be more robust and more linearly independent than their counterparts derived from Ward’s method, and clusters with comparable numbers of member days are more distinctive in terms of the standardized Euclidean distances of their centroids from the centroid of the dataset. The reproducible SOM clusters in the hemispheric domain are 1) the negative polarity of the North Atlantic Oscillation (NAO), 2) a pattern suggestive of Alaska blocking with a downstream wave train extending over North America and the North Atlantic, 3) an enhancement of the climatological-mean stationary wave pattern in the Western Hemisphere that projects positively upon the Pacific–North America (PNA) pattern, and 4) a pattern that projects upon the negative polarity of the PNA pattern. The first three patterns have important impacts on the wintertime climate in North America and Europe. In particular, they are helpful in interpreting prevailing flow patterns during the exceptional winters of 1930–31, 2009–10, and 2013–14. Because of the very limited number of independent samples in a single winter, the number of days per winter in which the circulation resides within individual clusters varies erratically from winter to winter, rendering attribution difficult.
Feline injection-site sarcoma
Authors: Hartmann Katrin , Day Michael J , Thiry Etienne , Lloret Albert , Frymus Tadeusz , Addie Diane , Boucraut-Baralon Corine , Egberink Herman , Gruffydd-Jones Tim , Horzinek Marian C , Hosie Margaret J , Lutz Hans , Marsilio Fulvio , Pennisi Maria Grazia , Radford Alan D , Truyen Uwe , Möstl Karin ,   European Advisory Board on Cat Diseases
Published: June 2015

Overview: In cats, the most serious of adverse effects following vaccination is the occurrence of invasive sarcomas (mostly fibrosarcomas): so-called ‘feline injection-site sarcomas’ (FISSs). These develop at sites of previous vaccination or injection. They have characteristics that are distinct from those of fibrosarcomas in other areas and behave more aggressively. The rate of metastasis ranges from 10–28%. Pathogenesis: The pathogenesis of these sarcomas is not yet definitively explained. However, chronic inflammatory reactions are considered the trigger for subsequent malignant transformation. Injections of long-acting drugs (such as glucocorticoids, and others) have been associated with sarcoma formation. Adjuvanted vaccines induce intense local inflammation and seem therefore to be particularly linked to the development of FISS. The risk is lower for modified-live and recombinant vaccines, but no vaccine is risk-free. Treatment and prevention: Aggressive, radical excision is required to avoid tumour recurrence. The prognosis improves if additional radiotherapy and/or immunotherapy (such as recombinant feline IL-2) are used. For prevention, administration of any irritating substance should be avoided. Vaccination should be performed as often as necessary, but as infrequently as possible. Non-adjuvanted, modified-live or recombinant vaccines should be selected in preference to adjuvanted vaccines. Injections should be given at sites at which surgery would likely lead to a complete cure; the interscapular region should generally be avoided. Post-vaccination monitoring should be performed.
Streptococcal infections in cats
Authors: Frymus Tadeusz , Addie Diane D , Boucraut-Baralon Corine , Egberink Herman , Gruffydd-Jones Tim , Hartmann Katrin , Horzinek Marian C , Hosie Margaret J , Lloret Albert , Lutz Hans , Marsilio Fulvio , Pennisi Maria Grazia , Radford Alan D , Thiry Etienne , Truyen Uwe , Möstl Karin ,   European Advisory Board on Cat Diseases
Published: June 2015

Overview: Streptococcus canis is most prevalent in cats, but recently S equi subsp zooepidemicus has been recognised as an emerging feline pathogen. infection: S canis is considered part of the commensal mucosal microflora of the oral cavity, upper respiratory tract, genital organs and perianal region in cats. The prevalence of infection is higher in cats housed in groups; and, for example, there may be a high rate of vaginal carriage in young queens in breeding catteries. A wide spectrum of clinical disease is seen, encompassing neonatal septicaemia, upper respiratory tract disease, abscesses, pneumonia, osteomyelitis, polyarthritis, urogenital infections, septicaemia, sinusitis and meningitis. infection: S equi subsp zooepidemicus is found in a wide range of species including cats. It was traditionally assumed that this bacterium played no role in disease of cats, but it is now considered a cause of respiratory disease with bronchopneumonia and pneumonia, as well as meningoencephalitis, often with a fatal course. Close confinement of cats, such as in shelters, appears to be a major risk factor. As horses are common carriers of this bacterium, contact with horses is a potential source of infection. Additionally, the possibility of indirect transmission needs to be considered. Diagnosis: Streptococci can be detected by conventional culture techniques from swabs, bronchoalveolar lavage fluid or organ samples. Also real-time PCR can be used, and is more sensitive than culture. Treatment: In suspected cases, treatment with broad-spectrum antibiotics should be initiated as soon as possible and, if appropriate, adapted to the results of culture and sensitivity tests.
Improved serological detection of rheumatoid arthritis: a highly antigenic mimotope of carbonic anhydrase III selected in a murine model by phage display
Authors: Araujo Galber Rodrigues , Vaz Emília Rezende , Fujimura Patricia Tiemi , Fonseca João Eurico , de Lima Lucélia Maria , Canhão Helena , Venturini Gabriela , Cardozo Karina Helena Morais , Carvalho Valdemir Melechco , Napimoga Marcelo Henrique , Goulart Luiz Ricardo , Gonçalves João , Ueira-Vieira Carlos 
Published: June 2015

Abstract
Introduction
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that affects around 1 % of the human population worldwide. RA diagnosis can be difficult as there is no definitive test for its detection. Therefore, the aim of this study was to identify biomarkers that could be used for RA diagnosis.

Methods
Sera from a collagen-induced arthritis mouse model were used to select potential biomarkers for RA diagnosis by phage display technology. In silico and in vitro analyses were performed to characterize and validate the selected peptides. Samples were classified into three groups: RA; two other immune-mediated rheumatic diseases (systemic lupus erythematosus (SLE) and ankylosing spondylitis (AS)); and healthy controls (HC). Enzyme-linked immunosorbent assay (ELISA) was carried out to determine antibody levels, and diagnostic parameters were determined by constructing receiver operating characteristic curves. Mass spectrometry and Western blot were performed to identify the putative autoantigen that was mimicked by a highly reactive mimotope.

Results
After three rounds of selection, 14 clones were obtained and tested for immunoreactivity analysis against sera from RA and HC groups. The phage-fused peptide with the highest immunoreactivity (M12) was synthesized, and was able to efficiently discriminate RA patients from SLE, AS and HCs (p < 0.0001) by ELISA. The specificity and sensitivity of anti-M12 antibodies for RA diagnosis were 91 % and 84.3 %, respectively. The M12 peptide was identified as one that mimics a predicted antigenic site of the carbonic anhydrase III (CAIII) protein, a ubiquitous biomarker that has been identified in patients with other diseases.

Conclusion
M12 is the first peptide associated with the CAIII protein that may be used as an antigen for antibody detection to aid in RA diagnosis with high sensitivity and specificity.
Exploratory study of tolerability and immunological effect of a short up‐dosing immunotherapy phase with a standardised allergen extract derived from pollen of Olea europaea
Authors: Moreno Carmen , De San Pedro Blanca Sáenz , Millán Carmen , Panizo Carmen , Martín Santiago , Florido Fernando 
Published: June 2015

AbstractBackgroundA new subcutaneous specific immunotherapy (SCIT) product adsorbed on aluminium hydroxide has been developed with a short and simplified up‐dosing phase, containing a biologically standardized allergen pollen extract from Olea europaea.ObjectiveTo assess the tolerability profile of the updosing phase and its immunological effect, in terms of specific IgG4 and IgE levels and immediate skin reactivity.Material and methodsThe study was an exploratory, multi‐centre, open‐label, single‐arm, phase II/III clinical trial. Adults with a clinical history of allergic rhinoconjunctivitis with/without asthma due to sensitization to olive pollen were selected. Five up‐dosing doses (300, 600, 3000, 6000 and 15000SQ+) were administered at weekly intervals, followed by a maintenance dose (15000SQ+) after 2 weeks. Adverse events were collected during the 30 min observation period after injections, after a telephone contact 2 days after each visit, and after reviewing the subjects’ diary. IgG4 and IgE levels and immediate skin reactivity were evaluated at the beginning and at the end of the trial.ResultsNinety‐three subjects were included in the trial (mean age, 35.7 ± 10.3 years; women, 66.7 %). A total of 95 adverse drug reactions, all mild in intensity and non‐serious, were reported during the trial: 85 local in 34.4 % subjects, 9 systemic in 4.3 % subjects and one non‐specific (grade 0). Within 6 weeks, significant changes in IgG4 and IgE levels and in immediate skin reactivity to Olea europaea were accomplished.ConclusionThis new SCIT derived from pollen of Olea europaea presented a good tolerability profile and induced significant immunological responses already after a 6 week treatment. However, the non‐controlled design may limit the interpretation of these results.Trial registrationEudraCT no: 2011‐004852‐20; ClinicalTrials.gov Identifier: NCT01674595.
Software-defined networking-based resource management: data offloading with load balancing in 5G HetNet
Authors: Duan Xiaoyu , Akhtar Auon Muhammad , Wang Xianbin 
Published: June 2015

Abstract
The explosive growth of mobile data traffic and the shortage of the available spectral resources have created new challenges for future cellular networks. In particular, resource management in heterogeneous network environment has become a critical issue. In this paper, we propose software-defined networking (SDN)-based resource management algorithms for future cellular network. Specifically, in this work, we have a threefold objective: i) alleviate spectrum shortage concerns by efficiently offloading traffic over the Wi-Fi network, ii) address network congestion by optimally balancing loads across multiple cells and iii) achieve the aforementioned objectives while taking network conditions and the end user quality-of-service (QoS) requirements into consideration. To this end, we present SDN-based partial data offloading and load balancing algorithms. The proposed algorithms exploit an SDN controller’s global view of the network and take optimized resource allocation decisions. We analyze the performance of the proposed algorithms under realistic network model. Moreover, we also present an analytical framework to quantify the delay incurred due to the SDN-based data processing and forwarding. Our analysis and system-level simulations show that the proposed load balancing algorithm significantly improves the equilibrium extent and network stability as compared to the baseline algorithms. On the other hand, the proposed partial data offloading algorithm is shown to satisfy end user’s quality-of-service while saving a significant amount of cellular resources.
Aging Population, Retirement, and Risk Taking
Authors: Levy Haim 
Published: June 2015

The increase in life expectancy spells disaster at retirement. One can solve this problem by investing in the maximum geometric mean (MGM) portfolio, which is empirically composed from equity. For a T = 30 year horizon or more, the MGM portfolio dominates other investment strategies by almost first-degree stochastic dominance. The MGM portfolio also maximizes the expected value of the commonly employed preferences and prospect theory value function, for various loss aversion parameters and various reference points, for T ≥ 10. Life-cycle funds would increase virtually all investors’ welfare by shifting to the MGM portfolio so long as the investment horizon is at least 10 years. This paper was accepted by Amit Seru, finance.
Designing hypermuscular neo-aristocracy: Of kings, gangsters and muscles in Indian cinema, fashion and politics
Authors: Kuldova Tereza 
Published: June 2015

Abstract
The article investigates the recent rise of the hypermuscular gangster as a hero in Bollywood cinema, a rise that coincides with the revival of royal aesthetics both in film and fashion. It argues that this idealized muscular gangster, the ultimate self-made man and favourite neoliberal hero, reinforces the simultaneous revival of pre-imperial authoritarian kingly models that manifest themselves not only on the fashion ramp, but also in the rise of right wing politics. In order to shed some light on these relations, the article draws a parallel to the 80s revival of masculinity in the US under Ronald Reagan and the recent election of the muscular Narendra Modi as the Indian Prime Minister. Consequently, it shows that the heroic gangsters and aristocrats, the low class and the elite, belong not only to the same aesthetic regime, but are the most blatant symbols of current political and economic ideology as well.
Expertise and the Economies of Knowledge of Architectural Practice in the Islamic World since 1800
Authors: Christensen Peter 
Published: June 2015

Abstract
The editorial introduction to this special volume presents the theme of this collection of articles: ‘expertise’ in the architecture of the Islamic world since 1800. Taken together, these articles address how the processes of empire building, modernisation, statecraft and diplomacy – some of the most common themes of architecture in the nineteenth, twentieth and twenty-first centuries – have been contingent on a web of expertise defined by a rich and varied array of authors and contexts. These studies demonstrate that while European and later North American agents and paradigms of expertise left a strong, often forceful, imprint on the architecture of the Islamic world, a number of dynamic forces internal to Islamic tradition, from the practices of gardening to mosque design, from the mural to the master plan, consistently inflected these imprints. They turn our attention away from an obsession with agency and historiography towards the vicissitudes and specificity of historical and cultural context.
Drawing Knowledge, (Re-)Constructing History: Pascal Coste in Egypt
Authors: Troelenberg Eva-Maria 
Published: June 2015

Abstract
This article looks at the work of the French architect Pascal Coste in Egypt. Muhammad Ali hired him primarily as an expert for infrastructure projects in 1817. Over the course of several years spent in Egypt, Coste also studied the main medieval monuments, particularly in Cairo. These studies were related to his plans for two revivalist mosques in Cairo and Alexandria (which were never realized). They also resulted in the publication of his seminal work Architecture Arabe ou Monuments du Kaire. Employing a process-based reading of the architect’s drawings, I seek to revisit Coste’s work as an engineer and an historian of architecture in and for Egypt. I will look at the role of the expert as intellectual agent, assess the notion of drawing as a medium for the establishment of cross-cultural knowledge and relate these observations to his more technical and applied work as an engineer. Through a critical assessment of the limits and possibilities of this expert’s cross-cultural agency, the case study of Coste also aims to offer an exemplary perspective on the role of the Muslim Middle East and related notions of tradition within the narrative of a larger modern Mediterranean world.
A Bourguibist Mural in the New Monastir? Zoubeïr Turki’s Play on Knowledge, Power and Audience Perception
Authors: Gerschultz Jessica 
Published: June 2015

Abstract
Zoubeïr Turki, a prominent artist of the Ecole de Tunis, painted the mural La Procession des Mourabtines in the lobby of the Hôtel Ribat in Monastir, Tunisia in 1962. Its iconography, patronage and position in Monastir’s architectural landscape elucidate the contentious and hierarchical relationships of power underwriting the art and tourism industries during the decade of Tunisian socialism (1961–1969). In this mural, Turki portrayed former president Habib Bourguiba leading a chain of murabitun (volunteer warriors) from the city’s landmark Islamic monument, its eighth-century ribat (a coastal fortress with military and religious functions). The artist’s dual reference to Tunisia’s Islamic history and Bourguiba’s burgeoning cult of personality testify to his engagement with claims to religious expertise in a contested political economy. With its various subtexts and ambiguities, the mural invites an interrogation of expertise and power in three concentric domains: the reforms of Habib Bourguiba and his administrative elite, the infrastructure supporting the installation of decorative programmes in state-owned hotels, and the audience’s capacity to conceptualize the mural within the discursive framework of modernization.