bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mechanistic Study on Ligand‐Controlled Cobalt‐Catalyzed Regioselectivity‐Switchable Hydroarylation of Styrenes
Authors: Yang Zhiwei , Yu Haizhu , Fu Yao 
Published: July 2013

AbstractDensity functional theory (DFT) calculations have been performed to study the mechanism of the recently reported Co‐catalyzed ligand‐controlled hydroarylation of styrenes as a means of preparing 1,1‐ or 1,2‐diarylalkanes. The present study corroborates the previously proposed three‐step mechanism, comprising CH activation (CH oxidative addition), styrene insertion, and reductive elimination. In the CH activation and reductive elimination steps, our calculations suggest that styrene does not coordinate to the Co center. In the insertion step, styrene is inserted into the CoH bond rather than the CoC bond. Furthermore, the rate‐ and regiodetermining step is found to be CC reductive elimination. It is significant that the regioselectivity observed experimentally has been successfully reproduced by our calculations. More importantly, in analyzing the origin of the ligand‐controlled regioselectivity, we have found that the steric effects of different ligands mainly determine the observed regioselectivity. Both the shape (i.e., “umbrella‐up” or “umbrella‐down”) and bulkiness of the ligand contribute to the steric effect.
Synthesis of 3,3‐Disubstituted Oxindoles by Palladium‐Catalyzed Asymmetric Intramolecular α‐Arylation of Amides: Reaction Development and Mechanistic Studies
Authors: Katayev Dmitry , Jia Yi‐Xia , Sharma Akhilesh K. , Banerjee Dipshikha , Besnard Céline , Sunoj Raghavan B. , Kündig E. Peter 
Published: July 2013

AbstractPalladium complexes incorporating chiral N‐heterocyclic carbene (NHC) ligands catalyze the asymmetric intramolecular α‐arylation of amides producing 3,3‐disubstituted oxindoles. Comprehensive DFT studies have been performed to gain insight into the mechanism of this transformation. Oxidative addition is shown to be rate‐determining and reductive elimination to be enantioselectivity‐determining. The synthesis of seven new NHC ligands is detailed and their performance is compared. One of them, L8, containing a tBu and a 1‐naphthyl group at the stereogenic centre, proved superior and was very efficient in the asymmetric synthesis of fifteen new spiro‐oxindoles and three azaspiro‐oxindoles often in high yields (up to 99 %) and enantioselectivities (up to 97 % ee; ee=enantiomeric excess). Three palladacycle intermediates resulting from the oxidative addition of [Pd(NHC)] into the aryl halide bond were isolated and structurally characterized (X‐ray). Using these intermediates as catalysts showed alkene additives to play an important role in increasing turnover number and frequency.
ChemInform Abstract: Disorder—Order Structural Transformation in Electron‐Poor Sr3Au8Sn3 Driven by Chemical Bonding Optimization.
Authors: Lin Qisheng , Vetter Jordan , Corbett John D. 
Published: July 2013

AbstractSr3Au8Sn3 is prepared by melting stoichiometric amounts of the metals (sealed Ta tube in evacuated silica jackets, 800 °C, 6 h; annealing at 400 °C, 1 week).
ChemInform Abstract: Synthesis and Crystal Structure of the New Selenogermanate, Cs2CdGe3Se8.
Authors: Hahn Song‐I , Kim Pilsoo , Yun Hoseop 
Published: July 2013

AbstractThe title compound is prepared from the elements in a CsCl flux (silica tube, 923 K, 5 d) and characterized by single crystal XRD.
ChemInform Abstract: Lithium Containing Rare‐Earth Metal Germanide, Er3.93Li1.07Ge4: Synthesis, Crystal Structure and Chemical Bonding.
Authors: Nam Gnu , Jeon Beom Yong , Kim Youngjo Kim Youngjo , Kang Sung Kwon , You Tae‐Soo 
Published: July 2013

AbstractThe title compound is prepared from a stoichiometric mixture of the elements (sealed Nb ampule, 1080 °C, 5 h and 750 °C, 2 d) and characterized by single crystal XRD and TB‐LMTO computations.
ChemInform Abstract: CsCdInQ3 (Q: Se, Te): New Photoconductive Compounds as Potential Materials for Hard Radiation Detection.
Authors: Kanatzidis Mercouri G. , et al. et al. 
Published: July 2013

AbstractCsCdInSe3 (I) and CsCdInTe3 (II) are prepared by reaction of In, Cs2Se3 or Cs2Te3, Cd, and Se or Te in a molar ratio of 2:1:2:3 ((I): 1.
ChemInform Abstract: La3Ni2SbO9: A Relaxor Ferromagnet.
Authors: Battle Peter D. , Evers Sophie I. , Hunter Emily C. , Westwood Mark 
Published: July 2013

AbstractA polycrystalline sample of La3Ni2SbO9 is prepared by solid state reaction of a stoichiometric mixture of Sb2O5, NiO, and Sb2O3 (alumina crucible, 1250 °C, 6 d).
ChemInform Abstract: Cluster Harvesting by Successive Reduction of a Metal Halide with a Nonconventional Reduction Agent: A Benefit for the Exploration of Metal‐Rich Halide Systems.
Authors: Stroebele Markus , Mos Agnieszka , Meyer Hans‐Juergen 
Published: July 2013

AbstractWCl6 and WBr6 are reduced with elemental iron and antimony, respectively.
ChemInform Abstract: Supported Au—Cu Bimetallic Alloy Nanoparticles: An Aerobic Oxidation Catalyst with Regenerable Activity by Visible‐Light Irradiation.
Authors: Sugano Yoshitsune , Shiraishi Yasuhiro , Tsukamoto Daijiro , Ichikawa Satoshi , Tanaka Shunsuke , Hirai Takayuki 
Published: July 2013

AbstractVisible‐light irradiation (<450 nm) of Au—Cu alloy nanoparticles supported on Degussa P25 TiO2 successfully promotes aerobic oxidation of 2‐propanol without significant catalyst deactivation.
ChemInform Abstract: Cs10H[Ga3H8]3: A Hydrogenous Zintl Phase Containing Propane‐Like Polyanions [Ga3H8]3‐ and Interstitial Hydrogen.
Authors: Fahlquist Henrik , Noreus Dag 
Published: July 2013

AbstractThe title compound is prepared by hydrogenation of a 1:1 Cs/Ga metal mixture (corundum crucible, autoclave, 50 bar H2, 588 K, 12 h) and characterized by powder X‐ray and neutron diffraction.
ChemInform Abstract: Facile Assembly of an Unusual Lead Borate with Different Cluster Building Units via a Hydrothermal Process.
Authors: Tian Han‐Rui , Wang Wen‐Hua , Gao Yan‐E , Deng Ting‐Ting , Wang Jia‐Ying , Feng Yun‐Long , Cheng Jian‐Wen 
Published: July 2013

AbstractThe first binodal 5,9‐connected lead borate Pb6B4O11(OH)2 is obtained by hydrothermal conversion of Pb(BO2)2·H2O (autoclave, 170 °C, 6 d, 33% yield).
ChemInform Abstract: The Ti‐BINOLate‐Catalyzed, Enantioselective Ring‐Opening of meso‐Aziridines with Amines
Authors: Peruncheralathan Saravan , Aurich Sandra , Teller Henrik , Schneider Christoph 
Published: July 2013

Abstractleading to a variety of trans‐1,2‐diamines
ChemInform Abstract: Greening the Wacker Process.
Authors: Kulkarni Mukund G. , Shaikh Yunnus B. , Borhade Ajit S. , Chavhan Sanjay W. , Dhondge Attrimuni P. , Gaikwad Dnyaneshwar D. , Desai Mayur P. , Birhade Deekshaputra R. , Dhatrak Nagorao R. 
Published: July 2013

AbstractThe novel protocol uses KBrO3 as the oxidant and Pd‐C as the catalyst and provides an environmentally benign alternative to the traditional Wacker system.
ChemInform Abstract: Various Oxidative Reactions with Novel Ion‐Supported (Diacetoxyiodo)benzenes.
Authors: Iinuma Masataka , Moriyama Katsuhiko , Togo Hideo 
Published: July 2013

AbstractTwo novel ion‐supported (diacetoxyiodo)benzenes are synthesized and successfully applied to the TEMPO‐mediated oxidation of alcohols [→ (II)], the oxidation of diisopropylbenzyl amines [→ (V)], the Hofmann rearrangement of primary amides [→ (VII)], the oxidative 1,2‐aryl migration of propiophenones [→ (X)] and the preparation of 5‐aryl‐2‐methyloxazoles from acetophenones [→ (XIII)].
ChemInform Abstract: Ruthenium Hydride‐Promoted Dienyl Isomerization: Access to Highly Substituted 1,3‐Dienes.
Authors: Clark Joseph R. , Griffiths Justin R. , Diver Steven T. 
Published: July 2013

AbstractRuthenium hydrides are found to promote the positional isomerization of 1,3‐dienes into more highly substituted 1,3‐dienes in a stereoconvergent manner.
ChemInform Abstract: Palladium‐Catalyzed Intramolecular Oxidative Heck Cyclization and Its Application Toward a Synthesis of (.+‐.)‐β‐Cuparenone Derivatives Supported by Computational Studies.
Authors: Ray Devalina , Nasima Yasmin , Sajal Mal K. , Ray Priyanka , Urinda Sharmistha , Anoop Anakuthil , Ray Jayanta K. 
Published: July 2013

AbstractThe novel methodology, applied to various homoallylic alcohols, leads to formation of cyclopentenone structures and is thus suitable in the synthesis of sesquiterterpene molecules.
ChemInform Abstract: Copper‐Catalyzed N‐ and O‐Alkylation of Amines and Phenols Using Alkylborane Reagents.
Authors: Sueki Shunsuke , Kuninobu Yoichiro 
Published: July 2013

AbstractThe copper‐catalyzed cross‐coupling reaction between aliphatic pinacol boronic acid esters and amines furnishes the corresponding secondary and tertiary amines in good to high yields.
ChemInform Abstract: Copper‐Catalyzed C—N Cross‐Coupling Reactions for the Preparation of Aryl Diamines Applying Mild Conditions.
Authors: Costa Marcio V. , Viana Gil M. , de Souza Thais M. , Malta Luiz Fernando B. , Aguiar Lucia C. S. 
Published: July 2013

AbstractThe process is investigated in the presence of Cu2O and CuO nanoparticles and CuO microparticles.
ChemInform Abstract: Nucleophilic Trifluoromethylation of Carbonyl Compounds: Trifluoroacetaldehyde Hydrate as a Trifluoromethyl Source.
Authors: Prakash G. K. Surya , Zhang Zhe , Wang Fang , Munoz Socrates , Olah George A. 
Published: July 2013

AbstractSubstrate (I) is applied as CF3CH (OH)2·1/2H2O.
ChemInform Abstract: Ruthenium‐Catalyzed Remote Electronic Activation of Aromatic C—F Bonds.
Authors: Watson Andrew J. A. , Atkinson Benjamin N. , Maxwell Aoife C. , Williams Jonathan M. J. 
Published: July 2013

AbstractFor the first time the tandem isomerization and nucleophilic aromatic substitution of allylic fluoro‐substituted benzylic alcohols is described.
ChemInform Abstract: C—H Arylation of Benzoquinone in Water Through Aniline Activation: Synergistic Effect of Graphite‐Supported Copper Oxide Nanoparticles.
Authors: Honraedt Aurelien , Le Callonnec Francois , Le Grognec Erwan , Fernandez Vincent , Felpin Francois‐Xavier 
Published: July 2013

AbstractThis is the first Meerwein arylation under heterogeneous catalysis.
ChemInform Abstract: Silver Ion Mediated in situ Synthesis of Mixed Diaryl Sulfides from Diaryl Disulfides.
Authors: Gogoi Prasanta , Gogoi Sandhya R. , Kalita Mukul , Barman Pranjit 
Published: July 2013

AbstractAgNO3 is used as an efficient reagent for the sulfenylation of phenol derivatives or indole to give the corresponding diaryl sulfides.
ChemInform Abstract: A Metal‐Free and Microwave‐Assisted Efficient Synthesis of Diaryl Sulfones.
Authors: Kumar Dalip , Arun V. , Pilania Meenakshi , Shekar K. P. Chandra 
Published: July 2013

AbstractVarious sulfinates react with a broad spectrum of symmetrical or unsymmetrical diaryliodonium salts to give the corresponding sulfones.
ChemInform Abstract: Palladium‐Catalyzed Desulfitative Cross‐Coupling Reaction of Sodium Sulfinates with Benzyl Chlorides.
Authors: Zhao Feng , Tan Qi , Xiao Fuhong , Zhang Shufeng , Deng Guo‐Jun 
Published: July 2013

AbstractThis method is based on the use of aromatic sodium sulfinates as aryl sources, affording diarylmethanes in moderate to good yields via extrusion of SO2.
ChemInform Abstract: A Soft Vinyl Enolization Approach to α‐Acylvinyl Anions: Direct Aldol/Aldol Condensation Reactions of (E)‐β‐Chlorovinyl Ketones.
Authors: Kim Hun Young , Li Jian‐Yuan , Oh Kyungsoo 
Published: July 2013

AbstractTreatment of the title compounds with NEt3 generates novel vinyl anion synthons which undergo aldol reaction with aldehydes to give aldol‐type allene structures.
ChemInform Abstract: Direct Acylation of N‐Benzyltriflamides from the Alcohol Oxidation Level via Palladium‐Catalyzed C—H Bond Activation.
Authors: Kim In Su , et al. et al. 
Published: July 2013

AbstractThe Pd‐catalyzed acylation of triflamides (I) and (IV) with alcohols (II) in the presence of tBuOOH leads selectively to ortho‐monoacylated products (III) and (V), whilst the analogous reaction of triflamide (VI) affords a mixture of mono‐ and diacylated products.
ChemInform Abstract: Monodispersed and Stable Nano Copper(0) from Copper‐Aluminum Hydrotalcite: Importance in C—C Couplings of Deactivated Aryl Chlorides.
Authors: Arundhathi Racha , Damodara Dandu , Mohan Kakita Veera , Kantam Mannepalli Lakshmi , Likhar Pravin R. 
Published: July 2013

AbstractThe catalytic system is effective in Heck‐, Suzuki‐, Stille‐ and Sonogashira cross‐coupling reactions.
ChemInform Abstract: Pd‐Catalyzed Selective Carbonylative and Non‐Carbonylative Couplings of Propiolic Acid: One‐Pot Synthesis of Diarylalkynones.
Authors: Kim Wonyoung , Park Kyungho , Park Ahbyeol , Choe Juseok , Lee Sunwoo 
Published: July 2013

AbstractDiarylalkynones are synthesized from one‐pot Pd‐catalyzed carbonylative and noncarbonylative coupling reactions of propiolic acid with aryl iodides under a carbon monoxide atmosphere.
ChemInform Abstract: Catalytic Activity of Palladium Acyclic Diaminocarbene Complexes in the Synthesis of 1,3‐Diarylpropynones via Sonogashira Reaction: Cross‐ versus Homo‐Coupling.
Authors: Ryabukhin Dmitry S. , Sorokoumov Viktor N. , Savicheva Elizaveta A. , Boyarskiy Vadim P. , Balova Irina A. , Vasilyev Aleksander V. 
Published: July 2013

AbstractDifferent acyclic diaminocarbene complexes (I)‐(III) can be efficiently used under air in an extremely low amount for the Sonogashira coupling of terminal alkynes with benzoyl chlorides.
ChemInform Abstract: Multicomponent Synthesis of 1‐[Aryl(p‐tolylsulfanyl)methyl]naphthalen‐2‐ols Using p‐Toluenesulfonic Acid as a Catalyst.
Authors: Hassanabadi Alireza 
Published: July 2013

AbstractThe title compounds (IV) are obtained in the one‐pot, three‐component reaction of 2‐naphthol, aromatic aldehydes, and thiols.
ChemInform Abstract: Selective Syntheses of Δα,β and Δβ,γ Butenolides from Allylic Cyclopropenecarboxylates via Tandem Ring Expansion/[3,3]‐Sigmatropic Rearrangements.
Authors: Xie Xiaocong , Li Yi , Fox Joseph M. 
Published: July 2013

AbstractAllylic cyclopropenecarboxylates engage in Rh‐catalyzed ring expansion reactions to deliver allyloxyfuran intermediates which subsequently rearrange into Δβ,γ butenolides, e.g. (II), via Claisen rearrangement or into the corresponding Δα,β butenolides, e.g. (VII), via further Cope rearrangement.
ChemInform Abstract: Preparation of Highly Functionalized Benzofurans from ortho‐Hydroxyphenones and Dichloroethylene: Applications and Mechanistic Investigations.
Authors: Schevenels Florian , Tinant Bernard , Declercq Jean‐Paul , Marko Istvan E. 
Published: July 2013

AbstractThe synthetic potential of the new method is demonstrated by the synthesis of the biologically active compounds nerolione (IV) and the lipoxygenase inhibitor (V).
ChemInform Abstract: Synthesis of Pentafluorosulfanyl‐Containing Indoles and Oxindoles.
Authors: Iakobson George , Posta Martin , Beier Petr 
Published: July 2013

AbstractThe title species are prepared from various nitro(pentafluorosulfanyl)benzene derivatives: catalytic hydrogenation of substrates (I) and (III) directly provides the target indoles; sulfon‐substituted substrates (VIII) are converted into 2‐arylindoles via nitro group reduction, imine formation, and base‐induced cyclization.
ChemInform Abstract: A Practical Regioselective Synthesis of Alkylthio‐ or Arylthioindoles Without the Use of Smelly Compounds such as Thiols.
Authors: Hamashima Toshihiko , Mori Yoshiaki , Sawada Kazunori , Kasahara Yuko , Murayama Daisuke , Kamei Yuto , Okuno Hiroaki , Yokoyama Yuusaku , Suzuki Hideharu 
Published: July 2013

AbstractA series of 3‐alkylthio‐ and 3‐arylthioindoles is prepared by treatment of indoles with sulfoxides and TFAA followed by dealkylation of resulting sulfonium perchlorates in refluxing dipropylamine.
ChemInform Abstract: Multicomponent Formation of Fused Pyrroles Through p‐TsOH Promoted N‐Arylation.
Authors: Li Ying , Li Qiu‐Yun , Xu Hai‐Wei , Fan Wei , Jiang Bo , Wang Shu‐Liang , Tu Shu‐Jiang 
Published: July 2013

AbstractA microwave‐assisted three‐component reaction leading to fused pyrroles bearing aromatic substituents is developed.
ChemInform Abstract: Gold‐Catalyzed Synthesis of Tetrahydrocarbazole Derivatives Through an Intermolecular Cycloaddition of Vinyl Indoles and N‐Allenamides.
Authors: Pirovano Valentina , Decataldo Laura , Rossi Elisabetta , Vicente Ruben 
Published: July 2013

AbstractThe direction of the intermolecular cycloaddition reaction of vinyl indoles (I) with N‐allenamides (II) depends on the reactant ratio and on the catalyst used leading to tetrahydrocarbazoles (III), (IV), or (V).
ChemInform Abstract: Suzuki—Miyaura Cross‐Coupling of Potassium Dioxolanylethyltrifluoroborate and Aryl/Heteroaryl Chlorides.
Authors: Fleury‐Bregeot Nicolas , Oehlrich Daniel , Rombouts Frederik , Molander Gary A. 
Published: July 2013

AbstractThis new sp3‐sp2 cross‐coupling protocol is based on the reliability and versatility of organotrifluoroborates, enables the facile introduction of dioxolanylethyl moieties onto aryl and heteroaryl halides, and complements previously reported methods leading to the same substructures.
ChemInform Abstract: Synthesis of Withasomnines and Their Non‐natural Analogues from Aldehydes and 4‐Nitro‐1‐butanol in Three Steps.
Authors: Verma Deepti , Kumar Rahul , Namboothiri Irishi N. N. 
Published: July 2013

AbstractA convenient, general and economical approach for the synthesis of the title pyrazole derivatives, with a 1,3‐dipolar cycloaddition as key‐step, is developed.
ChemInform Abstract: Copper‐Catalyzed N‐Arylation of 2‐Imidazolines with Aryl Iodides.
Authors: Davis Owen D. , Hughes Matthew , Bull James A. 
Published: July 2013

AbstractThe new, practical simple, and inexpensive title reaction affords a wide range of different substituted imidazoles with desirable lead‐like characteristics for early‐stage drug discovery.
ChemInform Abstract: Thiamine Hydrochloride (VB1)‐Catalyzed One‐Pot Synthesis of (E)‐N‐Benzylidene‐2‐phenyl‐1H‐benzo[d]imidazo[1,2‐a]imidazol‐3‐amine Derivatives.
Authors: Chen Fanglei , Lei Min , Hu Lihong 
Published: July 2013

AbstractA thiamine hydrochloride catalyzed three‐component one‐pot synthesis of the title compounds is described.
ChemInform Abstract: Aryl—Aryl Coupling via Palladium‐Catalyzed C—P/C—H Bond Cleavage.
Authors: Li Ziyuan , Zhou Haipin , Xu Jinyi , Wu Xiaoming , Yao Hequan 
Published: July 2013

AbstractThis is the first example of aryl‐aryl coupling via C—P/C—H bond cleavage using triaryl phosphines as coupling partners.
ChemInform Abstract: Copper‐Catalyzed Synthesis of Substituted Benzothiazoles via Condensation of 2‐Aminobenzenethiols with Nitriles.
Authors: Sun Yadong , Jiang Huanfeng , Wu Wanqing , Zeng Wei , Wu Xia 
Published: July 2013

AbstractA wide range of different functional groups is tolerated at the nitrile building block.
ChemInform Abstract: Regiocomplementary Cycloaddition Reactions of Boryl‐ and Silylbenzynes with 1,3‐Dipoles: Selective Synthesis of Benzo‐Fused Azole Derivatives.
Authors: Ikawa Takashi , Takagi Akira , Goto Masahiko , Aoyama Yuya , Ishikawa Yoshinobu , Itoh Yuji , Fujii Satoshi , Tokiwa Hiroaki , Akai Shuji 
Published: July 2013

AbstractIn the presence of iPr‐MgCl, 3‐borylbenzynes which are generated efficiently from new borolanes of type (I) undergo regiospecific, electrostatically controlled [3 + 2] cycloaddition with 1,3‐dipoles to afford proximal cycloadducts such as (III) and (VI).
ChemInform Abstract: Synthesis, Characterization and in vitro Anticancer Evaluation of Novel 1,2,4‐Triazolin‐3‐one Derivatives.
Authors: Kattimani Pramod P. , Kamble Ravindra R. , Kariduraganavar Mahadevappa Y. , Dorababu Atukuri , Hunnur Raveendra K. 
Published: July 2013

AbstractThe triazolinone derivative (IIIf), the most active triazole among the title compounds, shows nearly 50—99% growth inhibition of various tumor cell lines, even at micromolar concentrations.
ChemInform Abstract: Highly Enantiospecific Platinum‐Catalyzed Cycloisomerizations: Synthesis of Enantioenriched Oxabicycloheptene Derivatives.
Authors: Newcomb Eric T. , Ferreira Eric M. 
Published: July 2013

AbstractThe starting compounds are prepared according to literature by enantioselective ruthenium‐catalyzed reduction of the corresponding ketones followed by etherification.
ChemInform Abstract: Manganese Dioxide—Methanesulfonic Acid Promoted Direct Dehydrogenative Alkylation of sp3 C—H Bonds Adjacent to a Heteroatom.
Authors: Liu Xigong , Sun Bin , Xie Zhiyu , Qin Xiaojun , Liu Lei , Lou Hongxiang 
Published: July 2013

AbstractThe reagent combination efficiently promotes the alkylation of isochromans and Cbz‐protected tetrahydroisoquinolines with simple aromatic ketones and thus provides an attractive and environmentally friendly approach to these heterocycles.
ChemInform Abstract: One‐Step Synthesis of Isocoumarins and 3‐Benzylidenephthalides via Ligandless Pd‐Catalyzed Oxidative Coupling of Benzoic Acids and Vinylarenes.
Authors: Nandi Debkumar , Ghosh Debalina , Chen Shih‐Ji , Kuo Bing‐Chiuan , Wang Nancy M. , Lee Hon Man 
Published: July 2013

AbstractDifferent benzoic acids containing electron‐drawing groups can be converted into the corresponding coumarines or phtalides via the simple title reaction.
ChemInform Abstract: Chemoselective Suzuki—Miyaura Cross‐Coupling Reactions of 6‐Bromo‐3‐(trifluoromethylsulfonyloxy)flavone.
Authors: Akrawi Omer A. , Patonay Tamas , Konya Krisztina , Langer Peter 
Published: July 2013

AbstractThe reaction proceeds with very good chemoselectivity in favor of position 3, although usually bromides react faster than triflates.
ChemInform Abstract: Antihepatitis B Virus and Anticancer Activities of Novel Isoflavone Analogues.
Authors: Zhang Yikai , Zhong Hanyu , Lv Zhiliang , Zhang Mingfeng , Zhang Tao , Li Qisheng , Li Ke 
Published: July 2013

AbstractThe majority of the synthesized title compounds (III) and (V) shows inhibitory effects on HBsAg and HBeAg levels, HBV DNA replication, as well as the growth of four human cancer cell lines.
ChemInform Abstract: Synthesis, Structure Activity Relationship and Mode of Action of 3‐Substitutedphenyl‐1‐ (2,2,8,8‐tetramethyl‐3,4,9,10‐tetrahydro‐2H,8H‐pyrano [2,3‐f]chromen‐6‐yl)‐propenones as Novel Anticancer Agents in Human Leukaemia HL‐60 Cells.
Authors: Murthy Y. L. N. , Suhasini K. P. , Pathania A. S. , Bhushan S. , Sastry Y. Nagendra 
Published: July 2013

AbstractMost of the title compounds (V) inhibit the growth of aggressive cancer cell lines.
ChemInform Abstract: An Efficient Synthesis of Fluorinated Azaheterocycles by Aminocyclization of Alkenes.
Authors: Huang Hai‐Tsang , Lacy Tyler C. , Blachut Barbara , Ortiz Gerardo X. Jr. , Wang Qiu 
Published: July 2013

AbstractThe title synthesis can be achieved catalytically from the N‐chloroamines and NaI [e.g. reaction of (I)] or stoichiometrically from amine and NIS or NCS/NaI [reactions of (XX)].
ChemInform Abstract: A Silver(I)‐Catalyzed Tandem Reaction of 2‐Alkynylbenzaldoximes with Ketenes.
Authors: Liu Hongliang , Liu Gang , Pu Shouzhi , Wang Zhiyong 
Published: July 2013

AbstractThe 6‐endo‐cyclization of oximes (I) followed by reaction of intermediate isoquinoline‐N‐oxides with in situ generated ketenes leads to 3,4‐disubstituted isoquinolines (III).
ChemInform Abstract: New Anellated Thieno[2,3‐e][1,2,3]triazolo[1,5‐a]pyrimidines, with Potent Anticancer Activity, Designed Through VLAK Protocol.
Authors: Lauria Antonino , Abbate Ilenia , Patella Chiara , Martorana Annamaria , Dattolo Gaetano , Almerico Anna Maria 
Published: July 2013

AbstractA variety of new annelated thienotriazolopyrimidine derivatives with antitumor activity up to sub‐micromolar concentration are designed by combined use of the chemometric protocol Virtual Lock‐and‐Key (VLAK) and optimized synthetic procedures.
ChemInform Abstract: Novel Synthesis of Angular Thiazolo[5,4‐f] and [4,5‐h]Quinazolines, Preparation of Their Linear Thiazolo[4,5‐g] and [5,4‐g]Quinazoline Analogues.
Authors: Hedou Damien , Guillon Remi , Lecointe Charlotte , Loge Cedric , Chosson Elizabeth , Besson Thierry 
Published: July 2013

AbstractCompound (XI) is synthesized via established reactions as shown in the scheme.