bluuebunny/crossref_metadata_2025_split huggingface dataset:
Climate Variability and Change since 850 CE: An Ensemble Approach with the Community Earth System Model
Authors: Otto-Bliesner Bette L. , Brady Esther C. , Fasullo John , Jahn Alexandra , Landrum Laura , Stevenson Samantha , Rosenbloom Nan , Mai Andrew , Strand Gary 
Published: August 2015

Abstract
The climate of the past millennium provides a baseline for understanding the background of natural climate variability upon which current anthropogenic changes are superimposed. As this period also contains high data density from proxy sources (e.g., ice cores, stalagmites, corals, tree rings, and sediments), it provides a unique opportunity for understanding both global and regional-scale climate responses to natural forcing. Toward that end, an ensemble of simulations with the Community Earth System Model (CESM) for the period 850–2005 (the CESM Last Millennium Ensemble, or CESM-LME) is now available to the community. This ensemble includes simulations forced with the transient evolution of solar intensity, volcanic emissions, greenhouse gases, aerosols, land-use conditions, and orbital parameters, both together and individually. The CESM-LME thus allows for evaluation of the relative contributions of external forcing and internal variability to changes evident in the paleoclimate data record, as well as providing a longer-term perspective for understanding events in the modern instrumental period. It also constitutes a dynamically consistent framework within which to diagnose mechanisms of regional variability. Results demonstrate an important influence of internal variability on regional responses of the climate system during the past millennium. All the forcings, particularly large volcanic eruptions, are found to be regionally influential during the preindustrial period, while anthropogenic greenhouse gas and aerosol changes dominate the forced variability of the mid- to late twentieth century.
Characterization of Northern Hemisphere Snow Water Equivalent Datasets, 1981–2010
Authors: Mudryk L. R. , Derksen C. , Kushner P. J. , Brown R. 
Published: August 2015

Abstract
Five, daily, gridded, Northern Hemisphere snow water equivalent (SWE) datasets are analyzed over the 1981–2010 period in order to quantify the spatial and temporal consistency of satellite retrievals, land surface assimilation systems, physical snow models, and reanalyses. While the climatologies of total Northern Hemisphere snow water mass (SWM) vary among the datasets by as much as 50%, their interannual variability and daily anomalies are comparable, showing moderate to good temporal correlations (between 0.60 and 0.85) on both interannual and intraseasonal time scales. Wintertime trends of total Northern Hemisphere SWM are consistently negative over the 1981–2010 period among the five datasets but vary in strength by a factor of 2–3. Examining spatial patterns of SWE indicates that the datasets are most consistent with one another over boreal forest regions compared to Arctic and alpine regions. Additionally, the datasets derived using relatively recent reanalyses are strongly correlated with one another and show better correlations with the satellite product [the European Space Agency (ESA)’s Global Snow Monitoring for Climate Research (GlobSnow)] than do those using older reanalyses. Finally, a comparison of eight reanalysis datasets over the 2001–10 period shows that land surface model differences control the majority of spread in the climatological value of SWM, while meteorological forcing differences control the majority of the spread in temporal correlations of SWM anomalies.
Maintenance and Broadening of the Ocean’s Salinity Distribution by the Water Cycle
Authors: Zika Jan D. , Skliris Nikolaos , Nurser A. J. George , Josey Simon A. , Mudryk Lawrence , Laliberté Frédéric , Marsh Robert 
Published: August 2015

Abstract
The global water cycle leaves an imprint on ocean salinity through evaporation and precipitation. It has been proposed that observed changes in salinity can be used to infer changes in the water cycle. Here salinity is characterized by the distribution of water masses in salinity coordinates. Only mixing and sources and sinks of freshwater and salt can modify this distribution. Mixing acts to collapse the distribution, making saline waters fresher and fresh waters more saline. Hence, in steady state, there must be net precipitation over fresh waters and net evaporation over saline waters. A simple model is developed to describe the relationship between the breadth of the distribution, the water cycle, and mixing—the latter being characterized by an e-folding time scale. In both observations and a state-of-the-art ocean model, the water cycle maintains a salinity distribution in steady state with a mixing time scale of the order of 50 yr. The same simple model predicts the response of the salinity distribution to a change in the water cycle. This study suggests that observations of changes in ocean salinity could be used to infer changes in the hydrological cycle.
From evidence to policy: Findings from the Christchurch Health and Development Study
Authors: Fergusson David M , Boden Joseph M , Horwood L John 
Published: August 2015

The Christchurch Health and Development Study is a longitudinal study of a birth cohort of 1265 children who were born in Christchurch New Zealand in 1977. This cohort has now been studied from birth to the age of 35. This article examines a series of findings from the Christchurch Health and Development Study that address a range of issues relating to the measurement, explanation and prevention of crime and antisocial behaviour. These issues include: • The measurement of antisocial behaviour in middle childhood; • The effects of maternal smoking during pregnancy on later criminal offending; • The long-term consequences of conduct problems, self-control and attention deficits for later crime and delinquency; • The role of the marker for the monoamine oxidase (MAOA) genotype in moderating the associations between crime and life course predictors of crime; • The development of trajectory models of crime; • The use of fixed effects regression in longitudinal analyses to control non-observed sources of confounding; • Findings from evaluations of home visiting and parent behaviour management programmes. In general, the findings of the Christchurch Health and Development Study suggest that: (a) conduct problems in childhood and adolescence are a strong and consistent predictor of adult crime; (b) maternal smoking may be an important factor in the development of crime and antisocial behaviour; (c) individuals with the low activity variant of the marker for the MAOA genotype may be at particular risk of criminal offending in adulthood if exposed to environmental risks; (d) the linkages between alcohol misuse and criminal offending are specific to more impulsive kinds of crime such as assault and vandalism; and (e) that home visitation and parent behaviour management programmes may be effective in reducing both child abuse and childhood behaviour problems, amongst other beneficial effects. Two general themes unite this diverse portfolio of findings. The first has been the commitment of the Christchurch Health and Development Study research team to develop, pioneer and apply statistical methods for addressing long-standing issues relating to measurement and causal analysis in developmental data. The second has been the commitment of the group to translating research findings to develop well-evaluated evidence-based programmes.
Fast-food and full-service restaurant consumption in relation to daily energy and nutrient intakes among US adult cancer survivors, 2003–2012
Authors: An Ruopeng , Liu Junyi 
Published: August 2015

Background: Healthy diet is an essential component in cancer survivorship care planning. Cancer survivors should be particularly prudent regarding their daily food choices, with an aim of ensuring safe consumption, reducing risk of recurrence or other comorbidity, and improving quality of life. Objective: We aimed to examine the impacts of fast-food and full-service restaurant consumption on daily energy and nutrient intakes among US adult cancer survivors. Methods: Nationally representative data of 1308 adult cancer survivors came from the National Health and Nutrition Examination Survey 2003–2012 waves. First-difference estimator was adopted to address confounding bias from time-invariant unobservables like personal food/beverage preferences by using within-individual variations in diet and restaurant consumption status between two non-consecutive 24-hour dietary recalls. Results: Fast-food and full-service restaurant consumption, respectively, was associated with an increase in daily total energy intake by 125.97 and 152.26 kcal and sodium intake by 312.47 and 373.75 mg. Fast-food consumption was significantly associated with a decrease in daily vitamin A intake by 119.88 µg and vitamin K intake by 30.48 µg, whereas full-service restaurant consumption was associated with an increase in daily fat intake by 8.99 g and omega-6 fatty acid intake by 3.85 g, and a decrease in vitamin D intake by 0.93 µg. Compared with fast-food and full-service restaurant consumption at home, consumption away from home led to further reduced diet quality. Conclusions: Individualized nutrition counseling and food assistance programs should address cancer survivors’ overall dining-out behavior rather than fast-food consumption alone.
Health anxiety and depression in patients with fibromyalgia syndrome
Authors: Uçar Mehmet , Sarp Ümit , Karaaslan Özgül , Gül Ali Irfan , Tanik Nermin , Arik Hasan Onur 
Published: August 2015

Objectives To investigate health anxiety and depressive symptoms in patients with fibromyalgia syndrome (FMS). Methods Patients with FMS and healthy control subjects were recruited. All participants completed the Health Anxiety Inventory Short Form (HAI-SF) and Beck Depression Inventory (BDI). Pain was assessed in patients with FMS using the Fibromyalgia Impact Questionnaire (FIQ) and Visual Analogue Scale (VAS). Results This study involved 95 patients with FMS (15 male) and 95 healthy controls (17 male). Mean ± SD HAI-SF and BDI scores were significantly higher in patients with FMS = than in controls=. HAI-SF scores were 23.50 ± 10.78 and 9.38 ± 4.24 respectively; BDI scores were 18.64 ± 10.11 and 6.21 ± 4.05 respectively. There were highly significant correlations between FIQ and HAI-SF, FIQ and BDI, and HAI-SF and BDI. Conclusions Patients with FMS had significantly higher HAI-SF and BDI scores than healthy controls. Psychiatric support is essential for patients with FMS. Treatment should include biological, psychological and social approaches.
Polymorphism rs4263535 in GABRA1 intron 4 was related to deeper sedation by intravenous midazolam
Authors: Choi Yoon-Ji , Lee Shin Yuong , Yang Kyung-Sook , Park Ji-Young , Yoon Seung Zhoo , Yoon Suk Min 
Published: August 2015

Objective To evaluate whether polymorphisms in the gamma-aminobutyric acid A receptor α1 subunit ( GABRA1) gene influence sleep induction time, bispectral index score (BIS) during sleep induction and the total dose of midazolam required to reach a Ramsay Sedation Assessment Scale (RSAS) score of 4. Methods Patients scheduled for elective orthopaedic surgery were enrolled. All patients received initial doses of 0.02 mg/kg intravenous midazolam. If the RSAS score did not reach 4, an additional 1-mg dose of midazolam was administered. Results were compared among groups of patients with five single-nucleotide polymorphisms (SNPs) in GABRA1: rs4263535, rs980791, rs6556562, rs998754 and rs2279020. Results A total of 104 patients were evaluated. Polymorphism rs4263535 was associated with the lowest BIS during sedation induction. Multinomial logistic regression analysis demonstrated that polymorphism rs4263535 was significantly associated with the total dose of midazolam required for sedation induction. Conclusions Polymorphism rs4263535 in GABRA1 intron 4 was associated with deeper sedation by intravenous midazolam. Patients with the A/A rs4263535 genotype required a smaller dose of midazolam.
Strengths and Limitations of the MoCA for Assessing Cognitive Functioning
Authors: Coen Robert F. , Robertson Deirdre A. , Kenny Rose Anne , King-Kallimanis Bellinda L. 
Published: August 2015

Background: The Montreal Cognitive Assessment (MoCA) is a very widely used test for mild cognitive impairment. Differing recommendations have been made regarding its utility in providing a profile of performance across several cognitive domains. Objectives: To examine the factor structure of the MoCA in a nationally representative population study of older Irish adults and evaluate its utility in providing domain-specific information. Methods: A cross-sectional analysis of wave 1 data from the Irish Longitudinal Study on Ageing was undertaken. Data from a subset of 2342 participants assessed using the MoCA were analyzed using both confirmatory factor analytic (CFA) and exploratory factor analytic (EFA) methods. Results: Mean age was 72.64 (range 65 to 98), 53% female. The CFA provided evidence of adequate overall model fit for a previously proposed 6-factor model. In contrast, EFA yielded a 3-factor solution and test items cross-loaded onto a number of factors with no clear pattern of underlying cognitive domains. Using EFA to explore the 6-factor model yielded good fit, but again test items cross-loaded onto a number of factors with no clear pattern evident. Conclusion: Lack of concordance between the CFA and EFA findings demonstrates that the correspondence between individual tests and their assumed cognitive domains is not robust, reflecting at least in part a current lack of consensus on how core cognitive constructs are defined and on what subcomponents can be subsumed under different cognitive domains. The MoCA should not be viewed as a substitute for more in-depth neuropsychological assessment when domain-specific information is required.
The long journey toward a higher level of automation in ATM as safety critical, sociotechnical and multi-Agent system
Authors: Sáez Nieto Francisco Javier 
Published: August 2015

The main objective of this paper is to present our vision of the role of automation in future air traffic management (ATM) system. It also includes an analysis and state of the art on ATM and automation. The content is based on HALA! position paper, that looks beyond the framework defined by SESAR and NextGen for the near future, and analyses the feasibility of higher levels of automation in ATM in the far future, taking into account the relationship between humans, organizations, and machines and scoping the allocation of functions, roles, and tasks between them. Taking into consideration the proposed SESAR&NextGen paradigm shift (trajectory-based operations; proactive, more distributed and autonomous system) and studies developed in ATM automation in the past years, the vision goes toward a more ATM automation system operation questioning even the possibility of fully automated ATM system. The understanding of higher levels of automation in ATM considers the “overall system performance” as main driver for the resulting “optimal” ATM level of automation. Implementation of above programs will change the human role in the future ATM system. In this regard, the vision considers ATM as sociotechnical system and orchestrated organization, overcoming the former consequences of automation, where some “human errors” caused from automation were found, to this new vision where human motivation for their engagement in the ATM activities, will be promoted. New roles between humans, organizations, and between them and machines will be derived by considering ATM as a complex sociotechnical multi-agent system. Under this assumption, it will be essential: to maintain a high degree of autonomy among different ATM agents and, simultaneously, an optimized level of orchestration among them. Three interdependent criteria to support the always controversial decision about where to dynamically allocate the ATM essential functions/tasks are proposed; when is the “best time” to take an operational action, where is the “best place” having the best picture to take it and, finally, who will be the “best player” to implement the associated tasks. As a result, the paper advocates for a different role of automation devoted to support a temporal, institutional, and physical distributed ATM system. It is also pointed out that research in ATM automation should always take under consideration the adequate level of automation in the far future ATM system and should always ensure the safety and reliability of a highly automated ATM system. Finally considers the need to align the research efforts into two different main activities of improvement, devoted to: aircraft trajectory hierarchal, spatial, and temporal cohesion and trajectory management.
Whose business is it to employ Indigenous workers?
Authors: Hunter Boyd 
Published: August 2015

AbstractResearch about the demand for Indigenous labour and the relationship of Indigenous workers to their employers is relatively scarce. Even less is known about Indigenous businesses. Supply Nation defines an Indigenous business as those where Indigenous stakeholders hold majority equity, but some researchers have argued that this definition could be relaxed to include businesses in which Indigenous people hold only half the equity in the enterprise. This article uses data from the Industry Capability Network Queensland, which has collected basic business information on a large number of businesses operating in Queensland. The findings reveal that Indigenous businesses have substantially better outcomes for Indigenous employment than non-Indigenous businesses – a result that holds even when the definition of Indigenous business is relaxed. The article also documents how Indigenous employment is concentrated in larger businesses, in particular industry sectors. Non-Indigenous micro-businesses employ relatively few Indigenous workers, and future research can usefully explore why this is the case. To understand the issues involved, it will be necessary to collect multi-level data that link detailed information on employers and employees (including a substantial sample of Indigenous workers).
Defining the local nerve blocks for feline distal thoracic limb surgery: a cadaveric study
Authors: Enomoto Masataka , Lascelles B Duncan X , Gerard Mathew P 
Published: August 2015

Objectives Though controversial, onychectomy remains a commonly performed distal thoracic limb surgical procedure in cats. Peripheral nerve block techniques have been proposed in cats undergoing onychectomy but evidence of efficacy is lacking. Preliminary tests of the described technique using cadavers resulted in incomplete staining of nerves. The aim of this study was to develop nerve block methods based on cadaveric dissections and test these methods with cadaveric dye injections. Methods Ten pairs of feline thoracic limbs (n = 20) were dissected and superficial branches of the radial nerve (RSbr nn.), median nerve (M n.), dorsal branch of ulnar nerve (UDbr n.), superficial branch of palmar branch of ulnar nerve (UPbrS n.) and deep branch of palmar branch of ulnar nerve (UPbrDp n.) were identified. Based on these dissections, a four-point block was developed and tested using dye injections in another six pairs of feline thoracic limbs (n = 12). Using a 25 G × 5/8 inch needle and 1 ml syringe, 0.07 ml/kg methylene blue was injected at the site of the RSbr nn., 0.04 ml/kg at the injection site of the UDbr n., 0.08 ml/kg at the injection site of the M n. and UPbrS n., and 0.01 ml/kg at the injection site of the UPbrDp n. The length and circumference of each nerve that was stained was measured. Results Positive staining of all nerves was observed in 12/12 limbs. The lengths stained for RSbr nn., M n., UDbr n., UPbrS n. and UPbrDp n. were 34.9 ± 5.3, 26.4 ± 4.8, 29.2 ± 4.0, 39.1 ± 4.3 and 17.5 ± 3.3 mm, respectively. The nerve circumferences stained were 93.8 ± 15.5, 95.8 ± 9.7, 100 ± 0.0, 100 ± 0.0 and 93.8 ± 15.5%, respectively. Conclusions and relevance This described four-point injection method may be an effective perioperative analgesia technique for feline distal thoracic limb procedures.
Variation in avoidable emergency admissions: multiple case studies of emergency and urgent care systems
Authors: O’Cathain Alicia , Knowles Emma , Turner Janette , Hirst Enid , Goodacre Steve , Nicholl Jon 
Published: August 2015

Objective To identify factors affecting variation in avoidable emergency admissions that are not usually identified in statistical regression. Methods As part of an ethnographic residual analysis, we compared six emergency and urgent care systems in England, interviewing 82 commissioners and providers of key emergency and urgent care services. Results There was variation between the six cases in how interviewees described three parts of their emergency and urgent care systems. First, interviewees’ descriptions revealed variation in the availability of services before patients decided to attend emergency departments. Poor availability of general practice out of hours services in some of the cases reportedly made attendance at emergency departments the easier option for patients. Second, there was variation in how interviewees described patients being dealt with during their emergency department visit in terms of availability of senior review by specialists and in coding practices when patients were at risk of breaching the NHS’s 4-hour waiting time target. Third, there was variability in services described as facilitating discharge home from emergency departments. In some cases, emergency department staff described dealing with multiple agencies in multiple localities outside the hospital, making admission the easier option. In other cases, proactive multidisciplinary rapid assessment teams were described as available to avoid admissions. Perceptions of resources available out of hours and the extent of integration between different health services, and between health and social services, also differed by case. Conclusions This comparative case study approach identified further factors that may affect avoidable emergency admissions. Initiatives to improve GP out of hours services, make coding more accurately reflect patient experience, increase senior review in emergency departments, offer proactive multidisciplinary admission avoidance teams, improve the availability of out of hours care in the wider emergency and urgent care system, and increase service integration may reduce avoidable admissions. Evaluation of such initiatives would be necessary before wide-scale adoption.