bluuebunny/crossref_metadata_2025_split huggingface dataset:
Imunização e cobertura vacinal de crianças menores de 5 anos durante a pandemia de covid-19: revisão integrativa da literatura
Authors: Silva Tarciso Feijó da , Pereira Willy Cristine da Silva , Faria Magda Guimarães de Araújo , Martins Elaine Lutz , Silva Delson da , Nascimento Vagner Ferreira do 
Published: July 2024

Trata-se de uma revisão integrativa da literatura nacional e internacioanl que teve por objetivo identificar os fatores que contribuíram para diminuição da cobertura vacinal em menores de 5 anos durante a pandemia da Covid-19 e as ações desenvolvidas pelo enfermeiro para a garantia da adesão à vacinação na Atenção Primária à Saúde. A busca foi realizada nas bases de dados da Literatura Latino-americana e do Caribe em Ciências da Saúde, Medical Literature Analysis and Retrieval System Online e Scientific Electronic Library Online, considerando espaço temporal de 2018 até 2022. Constatou-se que a vacina é a forma mais eficaz e segura de prevenção contra as doenças imunopreveníveis e que a queda da cobertura vacinal coloca o Brasil em alerta para o risco do retorno de doenças outrora erradicadas. Dentre os fatores que afetam a adesão às vacinas estão a resistência, a incompatibilidade de horários, os problemas de saúde e socioeconômicos, a acessibilidade, a desinformação sobre as vacinas, e fragilidade na gestão na sala de vacinação que incorre em desabastecimento. Faz-se necessário que os profissionais da Atenção Primária à Saúde, em especial o profissional enfermeiro, promovam e fomentem ações, estratégias e planos de vacinação e comunicação para o alcance das coberturas vacinais, estabeleçam parcerias territoriais para a vacinação de recuperação e realizem monitoramento de usuários com vacinas em atraso.
Prevalence of nonalcoholic fatty liver disease in patients with hepatitis B: A meta-analysis
Authors: Zhang Li , Wu Hong-Di , Qian Yuan-Fang , Xu Hong-Yan 
Published: July 2024

BACKGROUND
The prevalence of nonalcoholic fatty liver disease (NAFLD) in patients with chronic hepatitis B (CHB) has increased in recent clinical practice; however, the relationship between CHB and hepatic steatosis (HS) remains controversial.
AIM
To shed light on the potential association between NAFLD and hepatitis B virus (HBV) infection.
METHODS
We conducted a systematic literature search using multiple databases, including PubMed, the Cochrane Library, Web of Science, and Embase, to identify relevant studies. Predefined inclusion criteria were used to determine the eligibility of the studies for further analysis.
RESULTS
Comprehensive meta-analysis software was used for statistical analysis, which covered 20 studies. The results indicated a lower NAFLD susceptibility in HBV-infected individuals (pooled OR = 0.87; 95%CI = 0.69-1.08; I 2 = 91.1%), with diabetes (P = 0.015), body mass index (BMI; P = 0.010), and possibly age (P = 0.061) as heterogeneity sources. Of note, in four studies (6197 HBV patients), HBV-infected individuals had a reduced NAFLD risk (OR = 0.68, 95%CI = 0.51-0.89, P = 0.006). A positive link between hyperlipidemia and metabolic syndrome emerged in hepatitis B patients, along with specific biochemical indicators, including BMI, creatinine, uric acid, fasting blood glucose, and homeostasis model assessment of insulin resistance.
CONCLUSION
HBV infection may provide protection against HS; however, the occurrence of HS in patients with HBV infection is associated with metabolic syndrome and specific biochemical parameters.
Sinonasal teratocarcinosarcoma involving the nasal cavity, unilateral paranasal sinuses, and intracranial invasion: A case report
Authors: Fu Li-Yuan , Yang Mi-Yang , Ye Pei-Yun , Wang Zhao-Chu , Chen Chu-Jie , Li Hui , Xu Shang-Wen 
Published: July 2024

BACKGROUND
Sinonasal teratocarcinosarcoma (SNTCS) is a rare and highly invasive neoplasm originating from the nasal cavity and sinuses. Typically, it exhibits an invasive behavior towards adjacent structures; however, in exceptional instances, it may infiltrate the intracranial compartment. Due to the tumor's rarity and lack of distinctive features on computed tomography (CT) and magnetic resonance imaging (MRI) images, SNTCS is often misdiagnosed.
CASE SUMMARY
In this study, we present a case of SNTCS in a 56-year-old patient who exhibited unexplained cognitive impairment before admission. CT and MRI scans revealed the presence of a mass in the right nasal cavity, with lesions extending to the right ethmoid sinus and right frontal region. Subsequently, the patient underwent pathological examination for confirmation and received surgical intervention to excise the tumor. The future advancement in our understanding of this disease will significantly contribute to the precise diagnosis and treatment of SNTCS.
CONCLUSION
SNTCS is an exceptionally rare malignant tumor that originates from the nasal cavity and paranasal sinuses, presenting a diagnostic challenge due to its non-specific imaging findings. MRI accurately delineates the location, morphological characteristics, size, internal structure, extent of surrounding involvement, and metabolic information of the lesion. These aspects play a pivotal role in the precise localization and qualitative assessment of SNTCS. Nevertheless, a definitive diagnosis still requires a pathological biopsy.
Solitary fibrous tumor: A case report of this multifaceted tumor
Authors: Maalouf Hani , Hadeer Ribal Aby , Ghattas Souad , Tabbikha Omar , Numan Hasan , Wakim Raja 
Published: July 2024

BACKGROUND
Solitary fibrous tumor (SFT) is a remarkably uncommon mesenchymal tumor. STAT6 level and a combination of clinical, pathological, and molecular features are required to arrive at a proper diagnosis.
CASE SUMMARY
In this report, we present an intriguing case involving a 43-year-old woman who initially exhibited symptoms of a bleeding retroperitoneal tumor, initially resembling a gastrointestinal stromal tumor, but later confirmed as an SFT. However, a year later, what was initially believed to be a recurrence of her SFT was instead identified as a desmoid tumor.
CONCLUSION
Distinguishing SFT from other tumors was pivotal. Correcting misdiagnoses of tumor type initially and of recurrence later was necessary for appropriate treatment of the correct desmoid type.
Severe acute pancreatitis complicated with intra-abdominal infection secondary to trauma: A case report
Authors: Zhang Yu , Cui Yun-Feng 
Published: July 2024

BACKGROUND
Pancreatic trauma (PT) is rare among traumatic injuries and has a low incidence, but it can still lead to severe infectious complications, resulting in a high mortality rate. Acute pancreatitis (AP) is a common complication after PT, and when combined with organ dysfunction and sepsis, it will result in a poorer prognosis.
CASE SUMMARY
We report a 25-year-old patient with multiple organ injuries, including the pancreas, due to abdominal trauma, who developed necrotising pancreatitis secondary to emergency caesarean section, combined with intra-abdominal infection (IAI). The patient underwent performed percutaneous drainage, pancreatic necrotic tissue debridement, and abdominal infection foci debridement on the patient.
CONCLUSION
We report a case of severe AP and IAI secondary to trauma. This patient was managed by a combination of conservative treatment such as antibiotic therapy and fluid support with surgery, and a better outcome was obtained.
Enhanced deep learning model for precise nodule localization and recurrence risk prediction following curative-intent surgery for lung cancer
Authors: Park Jihwan , Rho Mi Jung , Moon Mi Hyoung 
Published: July 2024

Purpose
Radical surgery is the primary treatment for early-stage resectable lung cancer, yet recurrence after curative surgery is not uncommon. Identifying patients at high risk of recurrence using preoperative computed tomography (CT) images could enable more aggressive surgical approaches, shorter surveillance intervals, and intensified adjuvant treatments. This study aims to analyze lung cancer sites in CT images to predict potential recurrences in high-risk individuals.

Methods
We retrieved anonymized imaging and clinical data from an institutional database, focusing on patients who underwent curative pulmonary resections for non-small cell lung cancers. Our study used a deep learning model, the Mask Region-based Convolutional Neural Network (MRCNN), to predict cancer locations and assign recurrence classification scores. To find optimized trained weighted values in the model, we developed preprocessing python codes, adjusted dynamic learning rate, and modifying hyper parameter in the model.

Results
The model training completed; we performed classifications using the validation dataset. The results, including the confusion matrix, demonstrated performance metrics: bounding box (0.390), classification (0.034), mask (0.266), Region Proposal Network (RPN) bounding box (0.341), and RPN classification (0.054). The model successfully identified lung cancer recurrence sites, which were then accurately mapped onto chest CT images to highlight areas of primary concern.

Conclusion
The trained model allows clinicians to focus on lung regions where cancer recurrence is more likely, acting as a significant aid in the detection and diagnosis of lung cancer. Serving as a clinical decision support system, it offers substantial support in managing lung cancer patients.
Employers’ requests when advertising for nurses—A national mapping of recruitment advertising for nurses in Sweden
Authors: Fröjd Camilla , Jangland Eva , Gunnarsson Anna-Karin 
Published: July 2024

Introduction
There is a shortage of nurses and many are leaving the profession. Maintaining sufficient nursing staff is a major healthcare challenge for societies worldwide. Work conditions, job orientation, and career opportunities all factor into nurses’ rates of attrition, exit, and turnover. Newly graduated nurses have requested structured introductory and/or mentoring programmes to ease their transition from education to work life and develop the skills and knowledge necessary in their particular work setting. Nurses also seek opportunities to continue learning and developing professionally.

Aims
To map and describe the content of recruitment advertisements for nurses. Research questions were: ‘What qualifications do healthcare employers request when recruiting nurses?’ and ‘What sorts of professional development do healthcare employers offer nurses?

Materials and methods
A comprehensive national mapping of recruitment advertisements for nurses in Sweden where all advertisements, N = 450, on 20 of the 21 regional hospital websites were collected. A qualitative and a quantitative content analysis was performed.

Results
Personal characteristics dominated requested competence in recruitment advertisements. Employers offered general nursing opportunities with unspecific work content and focused more on recruiting newly registered, rather than experienced, nurses. In only a few advertisements, employers asked for a master’s degree. No employer requested nurses with a PhD or research experience.

Conclusion
While the World Health Organization stresses the need for a sustainable recruitment and attainment of nurses to secure health care, employers’ recruitment of mostly newly graduated nurses and offering little professional development and few career opportunities may be one explanation for the difficulties in securing safe nurse staffing.
Incidence and determinants of low birth weight in Peninsular Malaysia: A multicentre prospective cohort study
Authors: Mansor Elliza , Ahmad Norliza , Mohd Zulkefli Nor Afiah , Lim Poh Ying 
Published: July 2024

Background and objective
Pregnant mothers are at risk of many adverse pregnancy outcomes, including infants with low birth weight (LBW). The World Health Organization aimed to achieve a 30% reduction in the number of LBW infants by the year 2025. In this study, we aimed to determine the incidence and determinants of LBW infants among pregnant mothers attending government health clinics in Peninsular Malaysia.

Material and methods
A prospective cohort study “Relative Risk of Determinants of Adverse Pregnancy Outcomes Among Pregnant Mothers Attending Government Health Clinics, Peninsular Malaysia, PEN-MUM” was conducted from March 2022 until March 2023 at 20 government health clinics in Peninsular Malaysia that were randomly selected through a multistage sampling method. Malaysian pregnant mothers between 18 and 49 years old were recruited at 12–18 weeks of gestation and followed up at three time points: 1 (24–28 weeks of gestation), 2 (36–40 weeks of gestation), and 3 (post-delivery). Eight exposure factors of LBW were studied: gestational weight gain, dengue infection, urinary tract infection, COVID-19 infection, gestational hypertension, preeclampsia, maternal anemia, and gestational diabetes mellitus (GDM).

Results
Among 507 participants enrolled in the cohort, 40 were lost to follow-up. A total of 467 were included in the final analysis, giving an attrition rate of 7.9%. The incidence of LBW infants in Peninsular Malaysia was 14.3%. After adjusting for three covariates (ethnicity, employment status, and gestational age at birth), three determinants of LBW were identified. The risk of giving birth to LBW infants was higher among those with inadequate gestational weight gain (aRR = 2.86, 95% CI: 1.12, 7.37, p = 0.03), gestational hypertension (aRR = 4.12; 95% CI: 1.66, 10.43; p = 0.002), and GDM (aRR = 2.21; 95% CI: 1.18, 4.14; p = 0.013) during the second and third trimesters.

Conclusions
The incidence of LBW infants in Peninsular Malaysia can be considered high. Having inadequate gestational weight gain, gestational hypertension, and GDM in the second and third trimesters increased the risk of LBW infants by threefold, fivefold, and twofold respectively. Thus, intervention strategies should target prevention, early detection, and treatment of gestational hypertension and GDM, as well as promoting adequate weight gain during antenatal care.
The Effect of Moringa Leaves Extract on Sperm Motility in Male Mice Exposed to Electromagnetic Radiation of Mobile Phone
Authors: Sabrina Hasnaa Alyasi , Budisulistyo Trianggoro , Juniarto Achmad Zulfa , Sareharto Tun Paksi 
Published: July 2024

Background: Electromagnetic radiation can induce an increase in oxidative stress. The presence of oxidative stress can impact the structure of the plasma membrane of sperm cells, damage the structure of Deoxyribonucleic Acid (DNA), and accelerate the process of apoptosis, ultimately leading to a decline in sperm quality. This increase in oxidative stress can be prevented by substances that serve as antioxidants. Moringa plants, particularly the leaves, contain various substances that can act as antioxidants for the body. These include flavonoids, alkaloids, saponins, tannins, and terpenoids. The antioxidant content in Moringa leaves is believed to safeguard the process of spermatogenesisAim: To determine the impact of Moringa (Moringa oleifera) leaf extract on the motility of spermatozoa in BALB/C mice subjected to exposure to electromagnetic waves.Methods: This study utilized design featuring a post-test-only control group design, dividing participants into four randomly assigned groups, namely a negative control group, a positive control group (exposure to electromagnetic waves), and 2 treatment groups (moringa leaf extract at dose of 100 mg/kg BW and 400mg/kg BW). Each group compromised 5 experimental animals, and the treatments were administered for duration of 30 days. Spermatozoa preparations were made for each group and observed under a microscope (400x). Data were analyzed by initially testing for normality using the Shapiro-Wilk test. If the data distribution was normal, the hypothesis examination involved conducting a One Way ANOVA followed by subsequent Post Hoc testing.Results: The results of the one-way ANOVA test indicated differences between groups of mice (p<0.05). The post hoc test results further demonstrated that a dose of 400 mg/kg BW was the most effective in preventing a decrease in spermatozoa motility. This effect is believed to be atttributed to the presence of vitamin C, beta carotene, beta-sitosterol, flavonoids, and polyphenols.Conclusion: There is an improvement in spermatozoa motility in BALB/C mice exposed to electromagnetic waves after the administration of Moringa leaf extract.
RNA‐sequencing reveals differential fibroblast responses to bleomycin and pneumonectomy
Authors: Wellmerling Jack H. , Dresler Sara R. , Meridew Jeffrey A. , Choi Kyoung M. , Tschumperlin Daniel J. , Tan Qi 
Published: July 2024

AbstractPulmonary fibrosis is characterized by pathological accumulation of scar tissue in the lung parenchyma. Many of the processes that are implicated in fibrosis, including increased extracellular matrix synthesis, also occur following pneumonectomy (PNX), but PNX instead results in regenerative compensatory growth of the lung. As fibroblasts are the major cell type responsible for extracellular matrix production, we hypothesized that comparing fibroblast responses to PNX and bleomycin (BLM) would unveil key differences in the role they play during regenerative versus fibrotic lung responses. RNA‐sequencing was performed on flow‐sorted fibroblasts freshly isolated from mouse lungs 14 days after BLM, PNX, or sham controls. RNA‐sequencing analysis revealed highly similar biological processes to be involved in fibroblast responses to both BLM and PNX, including TGF‐β1 and TNF‐α. Interestingly, we observed smaller changes in gene expression after PNX than BLM at Day 14, suggesting that the fibroblast response to PNX may be muted by expression of transcripts that moderate pro‐fibrotic pathways. Itpkc, encoding inositol triphosphate kinase C, was a gene uniquely up‐regulated by PNX and not BLM. ITPKC overexpression in lung fibroblasts antagonized the pro‐fibrotic effect of TGF‐β1. RNA‐sequencing analysis has identified considerable overlap in transcriptional changes between fibroblasts following PNX and those overexpressing ITPKC.
Evaluation of Internet of Things computer network security and remote control technology
Authors: Lu Haifeng , Wu Haiwei , Jing Ru 
Published: July 2024

Abstract
With the continuous improvement of China’s current technology level, the Internet of Things (IoT) technology is also increasingly widely used in various fields. IoT is a network composed of electronic components, software, sensors, etc. With the development of IoT technology, users’ demand for remote control equipment is increasingly urgent. In this article, the genetic algorithm–backpropagation neural network (GA–BPNN) algorithm was deeply studied by combining genetic algorithm (GA) and backpropagation neural network (BPNN) algorithm, and its application in network security evaluation was discussed. This article mainly studied the security and remote control technology of computer network and applied it to intelligent agriculture. In the evaluation performance test of the GA–BPNN algorithm, the evaluation accuracy of GA, BPNN, and GA–BPNN under simple difficulty was 99.58, 99.15, and 99.92%, respectively, and the evaluation accuracy under difficulty was 96.72, 96.47, and 98.88%, respectively. This proved the effectiveness of the GA–BPNN algorithm. In addition, in the application of smart agriculture, through the experimental data and concentration change data, it can be seen that the use of air-driven

CO

2

{\text{CO}}_{2}

(carbon dioxide) for concentration replenishment can effectively adjust the requirements of crops on the concentration of

CO

2

{\text{CO}}_{2}

. Through the analysis of the system’s light compensation system, it was proved that the system has a good structure and remarkable light compensation effect; it can replenish light for crops in time, and the PLC control structure has good working performance. The correctness of the system design was proved.
Clinical and pharmacogenetic features of patients with upper gastrointestinal lesions at a multidisciplinary hospital: the role of nonsteroidal anti-inflammatory drugs
Authors: Denisenko Natalia P. , Zhiryakova Anna S. , Sychev Ivan V. , Kryukov Alexander V. , Tuchkova Svetlana N. , Vakulenko Olga Y. , Averkov Oleg V. , Vechorko Valery I. , Mirzaev Karin B. , Sychev Dmitry A. 
Published: July 2024

Abstract

Objectives
Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most commonly prescribed medications, but their use can be associated with a number of adverse reactions, including upper gastrointestinal lesions. The aim of the study was to identify clinical and pharmacogenetic factors associated with upper gastrointestinal lesions, including those linked to NSAIDs, in patients at a multidisciplinary hospital.

Methods
The study included 92 patients (mean age 59.4±16.5 years; 47 women), who underwent esophagogastroduodenoscopy during inpatient treatment. Patients’ intake of NSAIDs and gastroprotectors during the year before hospitalization was considered. Demographic, clinical, laboratory data of patients were compared between groups, including genotyping for CYP2C9*2 rs179985, CYP2C9*3 rs1057910, CYP2C8*3 rs11572080, CYP2C8*3 rs10509681, PTGS-1 rs10306135, PTGS-1 rs12353214, and PTGS-2 rs20417 using real-time PCR.

Results
In NSAIDs+ patients, PTGS1 rs10306135 AT+TT genotypes increased the chance of developing gastrointestinal complications by 5.4 times (95 % CI=1.30–22.27). In total sample, smoking (OR=3.12, 95 % CI=1.15–8.46), and alcohol intake (OR=4.09, 95 % CI=1.05–15.87) increased odds of gastrointestinal damage. In NSAIDs+ patients omeprazole, famotidine and both famotidine and omeprazole during the last year were as ineffective as not taking gastroprotectors; in total sample famotidine (OR=0.19, 95 % CI=0.04–0.93) and two gastroprotectors (OR=0.13, 95 % CI=0.02–0.75) reduced the chance of upper gastrointestinal lesions.

Conclusions
Pharmacogenetic features of patients may significantly contribute to the development NSAIDs-induced upper gastrointestinal injuries.
Analysis of green energy regeneration system for Electric Vehicles and Re estimation of carbon emissions in international trade based on evolutionary algorithms
Authors: Gao Zhongpo , Yu Ao 
Published: July 2024

Abstract
In order to achieve maximum carbon reduction during the operation of pure electric buses, the author proposes a re estimation of carbon emissions in international trade based on evolutionary algorithm analysis of electric vehicle green energy regeneration systems. On the basis of analyzing single line scheduling, the author focuses on studying the regional scheduling mode of pure electric buses, and establishes a multi-objective optimization model for pure electric bus regional scheduling considering carbon benefits with the goals of minimizing the number of operating vehicles, minimizing the empty distance, and maximizing carbon benefits. Based on the actual operation data of pure electric buses 146 and 149 in a certain city, the author used an improved particle swarm optimization algorithm to solve the regional scheduling problem of pure electric buses according to the characteristics of the model. The results indicate that assuming other conditions remain unchanged, when the price of diesel rises to around 7.9 yuan, its operating costs will exceed those of pure electric buses, and the cost advantage of diesel vehicles will gradually decrease. Other conditions remain unchanged, and when the battery price per vehicle drops to around 300,000 yuan, the operating cost of pure electric buses will be lower than that of diesel vehicles. Conclusion: Under the premise of considering carbon benefits, adopting regional dispatch mode for pure electric buses has better economic efficiency and is more conducive to the promotion of pure electric buses.