bluuebunny/crossref_metadata_2025_split huggingface dataset:
Does the A9285g Polymorphism in Collagen Type XII α1 Gene Associate with the Risk of Anterior Cruciate Ligament Ruptures?
Authors: K. Ficek , M. Stepien-Slodkowska , M. Kaczmarczyk , A. Maciejewska-Karlowska , M. Sawczuk , J. Cholewinski , A. Leonska-Duniec , A. Zarebska , P. Cieszczyk , P. Zmijewski 
Published: December 2014

Abstract
One of the most severe injuries sustained by athletes is rupture of the anterior cruciate ligament (ACL). Recent investigations suggest that a predisposition for ACL rupture may be the result of specific genetic sequence variants. In light of this, we decided to investigate whether the COL12A1 A9285G polymorphism was associated with ACL ruptures in Polish football players.
We compared genotypic and allelic frequencies of the COL12A1 A9285G polymorphism in two groups of athletes: 91 male football players (23 ± 3 years) with surgically diagnosed primary ACL ruptures who qualified for ligament reconstruction (cases) and 143 apparently healthy, male football players of the same ethnicity, a similar age category, and a comparable level of exposure to ACL injury, who were without any self-reported history of ligament or tendon injury (controls). DNA samples extracted from the oral epithelial cells were genotyped by using a real-time polymerase chain reaction (Ri-Ti- PCR) method.
The genotype distribution in the cases were not different from those in controls (p = 0.70). The frequency of the G allele was lower in the cases (18.1%) but not statistically significant (p = 0.40) when compared with controls (21.3%).
Our results are in contradiction to the hypothesis that the COL12A1 A9285G polymorphism is associated with a predisposition for ACL injury. However, these conclusions should be supported with more experimental studies on COL12A1 polymorphisms.
Translocation t(3;12)(q26;q21) In Jak2V617F Point Mutation Negative Chronic Idiopathic Myelofibrosis: A Case Report
Authors: S. Mešanović , H. Šahović , M. Perić 
Published: December 2014

Abstract
The myeloproliferative diseases (MPDs) or myelo-proliferative neoplasms (MPNs) are a group of diseases of the bone marrow in which excess cells are produced. Chronic idiopathic myelofibrosis (CIMF) is a stem cell defect characterized by splenomegaly with multiorgan extramedullary hematopoiesis, immature peripheral blood granulocytes and erythrocytes and progressive bone marrow fibrosis. The most common chromosomal abnormalities seen in CIMF patients include numerical changes of chromosomes 7, 8 and 9, and structural changes of 1q, 5q, 13q and 20q. At least 75.0% of patients with bone marrow abnormalities have one or more of these chromosomal anomalies. Detection of the Janus kinase 2 (JAK2) mutation may be a potential major breakthrough for understanding the pathobiology of MPNs, and is an essential part of the diagnostic algorithm. In this study, we describe a JAK2V617F mutation negative CIMF patient who has the chromosomal translocation t(3;12)(q26;q21) in her karyotype.
Adult B Lymphoblastic Leukemia with a Novel De Novo Chromosomal Translocation [Der(9)t(9;12)(p24;q12),-12]: A Case Report
Authors: P.K. Gadhia , G.D. Shastri , E.G. Shastri 
Published: December 2014

Abstract
Patients suffering from adult acute lymphoblastic leukemia (ALL) are very ill and present most commonly with shortness of breath during physical activity, a pale complexion from anemia, a very low platelet count, the appearance of pinhead-sized red spots under the skin called petechiae, or prolonged bleeding from minor cuts and discomfort in the bones and joints. Fever in the absence of an obvious cause is common. Leukemic lymphoblasts may accumulate in the lymphatic system, and lymph nodes can be enlarged. We report a young adult male with a novel translocation in ALL, who had vague (uncertain) minimal symptoms and splenomegaly. The patient had a unique cytogenetic abnormality: 45,XY,der(9)t(9;12)(p24;q12),-12, which has not been previously described in ALL. This is categorized as a poor risk due to his failure to achieve complete remission after induction chemotherapy.
An Orchestrated Response To Tumor Signals By Macrophages and Mesenchymal Stem Cells Potentiates Interleukin-6 Secretion In Glioblastoma
Authors: Anton Kevin , Glod John 
Published: December 2014

AbstractThe tumor microenvironment plays a critical role in the survival, growth, invasion, and metastasis of solid tumors. However, the mechanisms by which it influences these aspects of tumor progression remain incompletely characterized. In this study, we show that human glioblastoma cells secrete soluble factors that alter the phenotype and cytokine secretion profile of both macrophages and mesenchymal stem cells (MSCs). Macrophages and MSCs respond to tumor-secreted factors by increasing the release of interleukin-6 (IL-6) and this response is potentiated when macrophages and MSCs are combined in co-culture. In glioblastoma, IL-6 has been associated with tumor cell invasion, angiogenesis, tumor cell proliferation, immune suppression, and poor prognosis. Our results suggest that the orchestrated response of macrophages and stromal elements to neoplastic cells enhances tumor progression through the release of soluble factors.
On Derivations of Operator Algebras with Involution
Authors: Širovnik Nejc , Vukman Joso 
Published: December 2014

Abstract
The purpose of this paper is to prove the following result. Let X be a complex Hilbert space, let L(X) be an algebra of all bounded linear operators on X and let A(X) ⊂ L(X) be a standard operator algebra, which is closed under the adjoint operation. Suppose there exists a linear mapping D : A(X) → L(X) satisfying the relation 2D(AA*A) = D(AA*)A + AA*D(A) + D(A)A*A + AD(A*A) for all A ∈ A(X). In this case, D is of the form D(A) = [A,B] for all A ∈ A(X) and some fixed B ∈ L(X), which means that D is a derivation.
On m-ω1-pω+n-Projective Abelian p-Groups
Authors: Danchev Peter 
Published: December 2014

Abstract
For any non-negative integers m and n, we define the classes of m-ω1-pω+n- projective groups and strongly m-ω1-pω+n-projective groups, which properly encompass the classes of ω1-pω+n-projectives introduced by Keef in J. Algebra Numb. Th. Acad. (2010) and strongly ω1-pω+n-projectives introduced by the present author in Hacettepe J. Math. Stat. (2014), respectively. The new group structures share many interesting properties, which are closely related to these of the aforementioned two own subclasses. Moreover, certain basic results in this direction are also established.
Generalizations of Opial-Type Inequalities in Several Independent Variables
Authors: Andric Maja , Barbir Ana , Pecaric Josip , Roqia Gholam 
Published: December 2014

Abstract
In this paper, we consider Willett’s and Rozanova’s generalizations of Opial’s inequality and extend them to inequalities in several independent variables. Also, we present some new Opial-type inequalities in several independent variables.
On Bi-Dimensional Second µ-Variation
Authors: Ereú Jurancy , Giménez José , Merentes Nelson 
Published: December 2014

Abstract
In this paper, we present a generalization of the notion of bounded slope variation for functions defined on a rectangle Ib
a in ℝ2. Given a strictly increasing function µ-defined in a closed real interval, we introduce the class BVµ,2 (Ib
a ), of functions of bounded second µ-variation on Ib
a ; and show that this class can be equipped with a norm with respect to which it is a Banach space. We also deal with the important case of factorizable functions in BVµ,2 (Ib
a ) and finally we exhibit a relation between this class and the one of double Riemann-Stieltjes integrals of functions of bi-dimensional bounded variation.
On the Nemytskii Operator in the Space of Functions of Bounded (p, 2, α)-Variation with Respect to the Weight Function
Authors: Aziz Wadie 
Published: December 2014

Abstract
In this paper, we consider the Nemytskii operator (Hf)(t) = h(t, f(t)), generated by a given function h. It is shown that if H is globally Lipschitzian and maps the space of functions of bounded (p,2,α)-variation (with respect to a weight function α) into the space of functions of bounded (q,2,α)-variation (with respect to α) 1<q<p, then H is of the form (Hf)(t) = A(t)f(t)+B(t). On the other hand, if 1<p<q then H is constant. It generalize several earlier results of this type due to Matkowski-Merentes and Merentes. Also, we will prove that if a uniformly continuous Nemytskii operator maps a space of bounded variation with weight function in the sense of Merentes into another space of the same type, its generator function is an affine function.
Radical Transversal Lightlike Submanifolds of Indefinite Para-Sasakian Manifolds
Authors: Shukla S.S. , Yadav Akhilesh 
Published: December 2014

Abstract
In this paper, we study radical transversal lightlike submanifolds and screen slant radical transversal lightlike submanifolds of indefinite para-Sasakian manifolds giving some non-trivial examples of these submanifolds. Integrability conditions of distributions D and RadTM on radical transversal lightlike submanifolds and screen slant radical transversal lightlike submanifolds of indefinite para-Sasakian manifolds, have been obtained. We also study totally contact umbilical radical transversal lightlike submanifolds of indefinite para-Sasakian manifolds.
Influence of the Collection Season on Production, Size, and Chemical Composition of Bee Pollen Produced by Apis Mellifera L.
Authors: Negrão Adriana F. , Barreto Lidia M. R. C. , Orsi Ricardo O. 
Published: December 2014

Abstract
The aim of our study was to investigate how the collection period affects and influences the production, chemical composition, and size of bee pollen loads (0.5, 1.0, 2.0, greater than 2.0 mm). The results showed there was a predominance of pollen loads with a diameter greater than 2.0 mm in all the production seasons. For all the seasons, there were no differences in protein content between the particle sizes. But when comparing 0.5 mm during the different periods, there were significant differences; the highest value was found during the winter (24.39 ± 3.7%). As far as lipids and crude fiber are concerned, we obtained differences between the same granulometry sizes for the spring and summer seasons. As for ashes, the results showed differences between different particle sizes for the summer and autumn seasons. Our results have shown that regardless of pollen particle size, its quality was not altered, suggesting that smaller loads can be commercially used by containing nutritional quality or else be used by beekeepers as a supplement during periods of food scarcity.
Pollen Foraging by Honey Bees (Apis Mellifera L.) in Greece: Botanical and Geographical Origin
Authors: Dimou Maria , Tananaki Chrysoula , Liolios Vasilios , Thrasyvoulou Andreas 
Published: December 2014

Abstract
Pollen is very important for honey bee colony development and nutrition. It is also a valuable product for human consumption, considered to have high nutritional value. In this study, we performed melissopalynological analysis of 285 pollen load samples collected from 44 apiaries throughout Greece. The analysis revealed 229 plant taxa represented in total. The abundance of each pollen type varied among the geographical areas from which the samples were collected. We also observed variation among samples collected from the same geographical region. The most frequently found families were Fabaceae, Asteraceae and Rosaceae. The most frequently observed taxa were Brassicaceae, Carduus type, Cistus and Papaver rhoeas. Statistical analysis showed that the geographical classification of pollen samples among northern, central and southern Greece is possible.
Changes in Alternative Splicing in Apis Mellifera Bees Fed Apis Cerana Royal Jelly
Authors: Shi Yuan Yuan , Huang Zachary Y. , Wu Xiao Bo , Wang Zi Long , Yan Wei Yu , Zeng Zhi Jiang 
Published: December 2014

Abstract
The Western honey bee (Apis mellifera) is a social insect characterized by caste differentiation in which the queen bee and worker bees display marked differences in morphology, behavior, reproduction, and longevity despite their identical genomes. The main causative factor in caste differentiation is the food fed to queen larvae, termed royal jelly (RJ). Alternative splicing (AS) is an important RNA-mediated post-transcriptional process in eukaryotes. Here we report AS changes in A. mellifera after being fed either A. mellifera RJ or A. cerana RJ. The results demonstrated that the RJ type affected 4 types of AS in adult A. mellifera: exon skipping, intron retention, alternative 5’ splice sites, and alternative 3’splice sites. After feeding with A. cerana RJ, AS occurred in many genes in adult A. mellifera that encode proteins involved in development, growth, the tricarboxylic acid cycle, and substance metabolism. This study provides the first evidence that heterospecific RJ can influence the AS of many genes related to honey bee development and growth.
Injuries of Worker Bees (Apis Mellifera Carnica) Stored in Own and Stranger Queenright Colonies
Authors: Zajdel Barbara , Gąbka Jakub , Jasiński Zygmunt , Beata Madras-Majewska 
Published: December 2014

Abstract
This research was conducted in 2008 and 2010 in the experimental apiary of the Warsaw University of Life Sciences. Worker bees were stored in transport cages in their own colonies and stranger colonies. The number of injuries and the death rate were checked twice, after 3 and 7 days of storage. In total, 6720 bees were examined (3360 workers from their own colonies and the same number from stranger colonies). The number of injured and dead workers had an exponential distribution (skewness>1). The worker bees sustained significantly more leg injuries (missing leg segments - 92 - 96%) than injuries of arolia (13 - 15%), wings (1 - 7%) or antennae (1 - 2). Worker bees stored in stranger colonies were injured significantly more frequently than worker bees stored in their own colonies. A significantly greater number of bees died in stranger colonies than in own colonies. The fact that bees stored in own colonies were injured proves that, even if they have the same smell, bees kept in cages provoke aggressive behavior from bees belonging to the banking colony.
Performance of Bee Colonies Headed by Queens Instrumentally Inseminated with Semen of Drones Who Come from a Single Colony or Many Colonies
Authors: Gerula Dariusz , Węgrzynowicz Paweł , Panasiuk Beata , Bieńkowska Małgorzata , Skowronek Wojciech 
Published: December 2014

Abstract
The aim of the study was to determine the effect of honey bee worker diversity within the colony on: development, honey productivity, and wintering. Two different levels of diversity within the colony were tested. The appropriate levels of diversity within the colony were obtained by selecting drones for inseminating the queens. Lower genetic diversity was obtained in the colonies headed by a queen inseminated with semen collected from drones originating from a single colony. Higher genetic diversity was obtained in the colonies with queens inseminated with semen from drones of 30 different colonies. Colonies with a higher genetic variation of workers in the colonies had greater levels of functional characteristics. However, apart from the number of dead bees in winter, the genetic diversity level of the workers on the colony development and honey production, did not have a significant influence. There was an averaging effect observed concerning that male component in the colonies with a higher genetic variation of workers - on honey yield, when compared to the non-additive effect of the best drones.
The Utility of Nonparametric Transformations for Imputation of Survey Data
Authors: Robbins Michael W. 
Published: December 2014

Abstract
Missing values present a prevalent problem in the analysis of establishment survey data. Multivariate imputation algorithms (which are used to fill in missing observations) tend to have the common limitation that imputations for continuous variables are sampled from Gaussian distributions. This limitation is addressed here through the use of robust marginal transformations. Specifically, kernel-density and empirical distribution-type transformations are discussed and are shown to have favorable properties when used for imputation of complex survey data. Although such techniques have wide applicability (i.e., they may be easily applied in conjunction with a wide array of imputation techniques), the proposed methodology is applied here with an algorithm for imputation in the USDA’s Agricultural Resource Management Survey. Data analysis and simulation results are used to illustrate the specific advantages of the robust methods when compared to the fully parametric techniques and to other relevant techniques such as predictive mean matching. To summarize, transformations based upon parametric densities are shown to distort several data characteristics in circumstances where the parametric model is ill fit; however, no circumstances are found in which the transformations based upon parametric models outperform the nonparametric transformations. As a result, the transformation based upon the empirical distribution (which is the most computationally efficient) is recommended over the other transformation procedures in practice.
Detecting and Treating Verified Influential Values in a Monthly Retail Trade Survey
Authors: Mulry Mary H. , Oliver Broderick E. , Kaputa Stephen J. 
Published: December 2014

Abstract
In survey data, an observation is considered influential if it is reported correctly and its weighted contribution has an excessive effect on a key estimate, such as an estimate of total or change. In previous research with data from the U.S. Monthly Retail Trade Survey (MRTS), two methods, Clark Winsorization and weighted M-estimation, have shown potential to detect and adjust influential observations. This article discusses results of the application of a simulation methodology that generates realistic population time-series data. The new strategy enables evaluating Clark Winsorization and weighted M-estimation over repeated samples and producing conditional and unconditional performance measures. The analyses consider several scenarios for the occurrence of influential observations in the MRTS and assess the performance of the two methods for estimates of total retail sales and month-to-month change.
Economic, Cultural and Social Factors Influencing the Development of Gay Businesses and Places: Evidence from the European Union / Ekonomické, Kulturní A Sociální Faktory V Pozadí Rozvoje Gay Podniků A Míst: Situace V Evropské Unii
Authors: Gabiam Koessan , Pitoňák Michal 
Published: December 2014

Abstract
The late 20th century emergence of gay neighbourhoods and their related businesses has been examined by a number of researchers, but few have tackled this issue on a larger scale compared to case studies in a national context. This study considers the development of European gay businesses and gay non-residential places, using principal components analysis on data from the Spartacus International Gay Guide of 2007. This is an unusual quantitative approach in the largely qualitatively-dominated field of geographies of sexualities. It has identified gay commodification and gay (in)visibilities as the most likely factors of spatial diversity in observed gay places. These two identified dimensions are then analysed in terms of their linkages, specificities and regional importance. Subsequently, the interactions between economic, cultural and social factors at stake in the development of gay business and non-residential places across Europe, are evaluated.
Shopping and Services Related Travel in the Hinterland of Brno: Changes From the Socialist Period to the Present / Spádovost Za Obchodem A Službami V Zázemí Brna: Srovnání Období Socialismu A Současnosti
Authors: Maryáš Jaroslav , Kunc Josef , Tonev Petr , Szczyrba Zdeněk 
Published: December 2014

Abstract
Shopping and services related travel represent significant aspects of the service functions of settlements and belong to basic region-forming processes. They are relatively irregular movements, and the analyses of these processes are based on data which are not available from official sources. This article presents some results from a survey on the attraction of retail and services provision, as exemplified by service processes in the hinterland of Brno City. The results from our survey contain both a time dimension in a single-model space (in terms of a comparison between current results and those from the socialist era at the end of the 1970s), and the possibility to compare various methodologies using responses from municipalities and those from local residents. Hence, this article presents an outline of selected changes in the shopping resources and shopping and services related travel in the Brno hinterland, over a period of about three decades, with some interesting methodological aspects.
The Identification of Residents with their Region and the Continuity of Socio-Historical Development / Identifikace Obyvatel Se Svým Regionem A Kontinuita Socio-Historického Vývoje
Authors: Šerý Miloslav 
Published: December 2014

Abstract
The regional identity of inhabitants in typologically different regions, which differ mainly in terms of the continuity of their socio-historical development, is examined in this article using the example of two case study areas. An important dimension of the concept of any population’s regional identity is the phenomenon of the identification of inhabitants with their region, and this is subject to analysis in this paper. The research demonstrated that a stronger form of the identity phenomenon could be reported for the case study region in which socio-historical development had an uninterrupted continuity. The observed findings helped to confirm the importance of long-term processes in a region’s formation.
Hydrodechlorination of tetrachloromethane over silica-supported palladium-gold alloys
Authors: Karpiński Zbigniew , Bonarowska Magdalena , Juszczyk Wojciech 
Published: December 2014

Abstract
Compared with the monometallic palladium, bimetallic Pd-Au/SiO2 catalysts show much higher activity and better stability in the reaction of hydrodechlorination of tetrachloromethane, also providing higher selectivity to longer than methane hydrocarbon products. Reasonably mixed Pd-Au particles show better catalytic performance during ~60 h operation, whereas the monometallic palladium and very rich in palladium catalysts suffer rapid deactivation. Smaller amounts of carbon- and chlorine-containing deposits found after reaction on Pd-Au catalysts correspond to their superior catalytic behavior.
The study of glycerol-based fermentation and broth downstream by nanofiltration
Authors: Gryta Marek , Markowska-Szczupak Agata , Grzechulska-Damszel Joanna , Bastrzyk Justyna , Waszak Marta 
Published: December 2014

Abstract
In this work, the glycerol fermentation was carried out using Citrobacter freundii bacteria. The influence of glycerol and metabolites concentrations, and the pH changes on the efficiency of 1,3-propanediol production, during batch and fed-batch processes, was presented. The nanofiltration was used for the separation of obtained post-fermentation solutions. The resulted 1,3-PD solutions were significantly desalted, which may facilitate further downstream processes during 1,3-PD production.
Unusual Clinical Manifestations of Chronic Discoid Lupus Erythematosus
Authors: Miteva Ljubka , Broshtilova Valentina , Schwartz Robert A. 
Published: December 2014

Abstract
A 22-year-old woman with a 3-year history of discoid lupus erythematosus presented with two circumscribed patches of non-scarring alopecia, clinically simulating alopecia areata. Histopathological analysis of scalp lesions revealed discoid lupus erythematosus. Based on the clinical history, physical examination, and histological and immunological findings, we distinguished our case from a true combination of alopecia areata and typical chronic discoid lupus erythematosus.