bluuebunny/crossref_metadata_2025_split huggingface dataset:
Raptinal: a powerful tool for rapid induction of apoptotic cell death
Authors: Smith Amanda J. , Hergenrother Paul J. 
Published: August 2024

AbstractChemical inducers of apoptosis have been utilized for decades as tools to uncover steps of the apoptotic cascade and to treat various diseases, most notably cancer. While there are several useful compounds available, limitations in potency, universality, or speed of cell death of these pro-apoptotic agents have meant that no single compound is suitable for all (or most) purposes. Raptinal is a recently described small molecule that induces intrinsic pathway apoptosis rapidly and reliably, and consequently, has been utilized in cell culture and whole organisms for a wide range of biological studies. Its distinct mechanism of action complements the current arsenal of cytotoxic compounds, making it useful as a probe for the apoptosis pathway and other cellular processes. The rapid induction of cell death by Raptinal and its widespread commercial availability make it the pro-apoptotic agent of choice for many applications.
Mutual reinforcement of land-based carbon dioxide removal and international emissions trading in deep decarbonization scenarios
Authors: Morris Jennifer , Gurgel Angelo , Mignone Bryan K. , Kheshgi Haroon , Paltsev Sergey 
Published: August 2024

AbstractCarbon dioxide removal (CDR) technologies and international emissions trading are both widely represented in climate change mitigation scenarios, but the interplay among them has not been closely examined. By systematically varying key policy and technology assumptions in a global energy-economic model, we find that CDR and international emissions trading are mutually reinforcing in deep decarbonization scenarios. This occurs because CDR potential is not evenly distributed geographically, allowing trade to unlock this potential, and because trading in a net-zero emissions world requires negative emissions, allowing CDR to enable trade. Since carbon prices change in the opposite direction as the quantity of permits traded and CDR deployed, we find that the total amount spent on emissions trading and the revenue received by CDR producers do not vary strongly with constraints on emissions trading or CDR. However, spending is more efficient and GDP is higher when both CDR and trading are available.
Interference haptic stimulation and consistent quantitative tactility in transparent electrotactile screen with pressure-sensitive transistors
Authors: Lim Kyeonghee , Lee Jakyoung , Kim Sumin , Oh Myoungjae , Koh Chin Su , Seo Hunkyu , Hong Yeon-Mi , Chung Won Gi , Jang Jiuk , Lim Jung Ah , Jung Hyun Ho , Park Jang-Ung 
Published: August 2024

AbstractIntegrating tactile feedback through haptic interfaces enhances experiences in virtual and augmented reality. However, electrotactile systems, which stimulate mechanoreceptors directly, often yield inconsistent tactile results due to variations in pressure between the device and the finger. In this study, we present the integration of a transparent electrotactile screen with pressure-sensitive transistors, ensuring highly consistent quantitative haptic sensations. These transistors effectively calibrate tactile variations caused by touch pressure. Additionally, we explore remote-distance tactile stimulations achieved through the interference of electromagnetic waves. We validated tactile perception using somatosensory evoked potentials, monitoring the somatosensory cortex response. Our haptic screen can stimulate diverse electrotactile sensations and demonstrate various tactile patterns, including Morse code and Braille, when integrated with portable smart devices, delivering a more immersive experience. Furthermore, interference of electric fields allows haptic stimulation to facilitate diverse stimulus positioning at lower current densities, extending the reach beyond direct contact with electrodes of our screen.
Localization and Speech-in-Noise Performance in a Virtual Reality Test Environment: A Pilot Study of Adults With Single-Sided Deafness Using a Cochlear Implant
Authors: Sladen Douglas P. , Diedesch Anna C. , Zeitler Daniel M. 
Published: August 2024

Purpose:
The purpose of this exploratory study was to (a) construct a virtual reality (VR) test environment to measure speech recognition in noise (SIN) and localization, and (b) use the VR test environment to establish degree of binaural hearing benefit among a small number of adults with single-sided deafness (SSD) using a cochlear implant (CI).

Method:
This pilot study included five adults implanted for SSD. The test environment was composed of an eight-speaker array that delivered restaurant noise and Institute of Electrical and Electronics Engineers sentences. VR head-mounted display goggles delivered a video recording of a busy restaurant. Participants completed SIN and localization in two conditions: (a) normal-hearing ear and a CI on the contralateral SSD side (CI-ON) and (b) normal-hearing ear and unaided on the contralateral SSD side (CI-OFF).

Results:
Overall, CI benefits for SIN and localization within the VR test environment were improved for some participants, although not all. CI benefit for SIN and localization was dependent on speaker location.

Conclusions:
VR test environments present new opportunities for studying SIN and localization abilities in participants with CIs. This pilot study shows that, within a VR test environment, degree of CI benefit among SSD participants for SIN and localization varies across speaker location and across participants.
Multi‐energy system horizon planning: Early decarbonisation in China avoids stranded assets
Authors: Zhou Xiaowei , Strunz Kai , Brown Tom , Sun Hongbin , Neumann Fabian 
Published: August 2024

AbstractAn appropriate decarbonisation pathway is crucial to achieving carbon neutrality in China before 2060. This paper studies decarbonisation pathways for China's energy system between 2020 and 2060 using an open, provincial, and hourly resolved, networked model within the context of multi‐period planning with myopic investment foresight. Two representative decarbonisation pathways are compared, with particular attention to the synergies of coupling the electricity and heating sectors. An early and steady path in which emissions are strongly reduced in the first decade is more cost‐effective than following a late and rapid path. Early decarbonisation in the electricity sector avoids stranded investments in fossil infrastructure and preserves the carbon budget for later emissions in the difficult‐to‐decarbonise heating sector. Retrofitting the existing coal power plants by adding carbon capture facilities is cost‐effective in both decarbonisation pathways. The hourly and non‐interrupted resolution for a full weather year reveals the balancing strategies of highly renewable, sector‐coupled systems. The significant seasonal variation of heat demand dominates long‐term storage behaviours.
Design of super wide band 3‐way power divider/combiner
Authors: Mungara Nagarakshith , Ray Kamla Prasan 
Published: August 2024

AbstractA 1:3‐way power divider/combiner has been proposed for much improved bandwidth and isolation between output ports. The matching network for the super wide bandwidth frequency range is designed using a combination of the Klopfenstein taper and the triangular taper. The proposed design yields bandwidth from 1.5 to 20 GHz (18.5 GHz) for return loss better than 15 dB and isolation better than 20 dB. The insertion loss for the entire frequency band is 0.8 dB which is only 0.34 dB for the ultra‐wide bandwidth (3.1–10.6 GHz). The maximum phase imbalance of 3.32° and amplitude imbalance of 0.199 dB between all the output ports have been achieved over the entire bandwidth. The simulated results have been validated experimentally.
Use of a slow-release GnRH implant in an adult billy
goat
Authors: Demattio Lukas , Fietz Daniela , Schuler Gerhard , Wehrend Axel 
Published: August 2024

AbstractA 9.4 mg deslorelin slow-release implant was inserted into an adult, healthy
billy goat to achieve temporary infertility and a reduction in sexual behavior.
The implant was inserted in late autumn. No significant change in testis size
was observed over the following 6 weeks. The endocrine function of the testis,
which was examined by stimulation with human chorionic gonadotropin, was also
unchanged after 6 weeks compared to the initial examination. Histological
examination revealed a preserved spermatogenesis.In conclusion, the application of a GnRH analogue implant in the adult male goat
has no influence on the investigated parameters – and thus probably also on its
fertility.
Developing and Implementing a Clinical Informatics Curriculum
Authors: Spiegelman Lindsey , Rudkin Scott , Portillo Sonia , O'Connell Ryan 
Published: August 2024

Abstract
Objectives We developed and implemented a customized internal clinical informatics (CI) curriculum for the UC Irvine CI Fellowship program. The goal was to transition from an externally sourced curriculum to a more focused, internally developed program, aligning with feedback from early fellows and the evolving practical needs of clinical informatics. By designing this curriculum in-house, we sought to provide a more efficient, cost-effective, and relevant educational experience for fellows.
Methods The curriculum was designed over a one-year period, beginning in July 2021 and launched in July 2022. The development process involved collaboration among core clinical informatics faculty, organizing the content into 13 thematic blocks, each spanning four weeks. Each block included a mix of pre-recorded lectures for asynchronous learning and interactive sessions for applied, synchronous learning. The curriculum was designed to cycle twice over the course of the two-year fellowship, with second-year fellows taking on greater teaching responsibilities to solidify their knowledge. Feedback was gathered from graduating fellows and used to iteratively refine the content and structure.
Results Feedback from fellows during the first year of implementation was overwhelmingly positive, with evaluations indicating high satisfaction regarding the relevance, focus, and practical application of the content. Quantitative and qualitative feedback suggested that fellows found the internal curriculum more aligned with their learning goals compared to the prior external curriculum. Modifications were made based on fellow input to adjust the number and structure of interactive sessions, ensuring high-yield learning.
Conclusion This case study highlights the successful development and implementation of a customized clinical informatics curriculum at UC Irvine. The curriculum offers a more tailored, responsive, and comprehensive educational model, addressing both financial constraints and the need for a practical, focused learning experience. This initiative provides valuable insights and a potential framework for other institutions seeking to transition to an internal informatics curriculum.
The intrinsic ferromagnetic half-metals with high Curie temperature of tetragonal XCrS4 (X=Ti, Zr) monolayer
Authors: Sun Hongtong , Yin Chunhao , Zhao Zihao , Gao Jianing , Wang Xing 
Published: August 2024

Two-dimensional intrinsic magnetic materials with a high Curie temperature (TC) and 100% spin-polarization are highly desirable for creating spintronic devices. In this work, the electronic structure and intrinsic magnetism of XCrS4 (X = Ti, Zr) monolayers are predicted by using first-principles calculations. XCrS4 (X = Ti, Zr) monolayer materials exhibit excellent dynamical, thermal, and dynamically stable stability and small binding energy. The band structures show that XCrS4 (X = Ti, Zr) monolayers are intrinsic ferromagnetic (FM) half-metals with wide half-metallic gaps. Monte Carlo simulations based on the Heisenberg model are used to estimate the Curie temperature (TC) of the TiCrS4 (73 K) and ZrCrS4 (216 K) monolayers. The magnetic performances can be significantly modulated by strain; the TiCrS4 monolayer can undergo FM to antiferromagnetic phase transition under certain uniaxial and biaxial strains. The results indicate that the intrinsic half-metals with higher TC and controllable magnetic properties make XCrS4 (X = Ti, Zr) monolayers enrich the application of nanoscale spintronic devices.
Effects of magnetic field topography on the ion thruster discharge chamber performance
Authors: Chen Juanjuan , Geng Hai , Meng Wei , Yan Nengwen , Hu Jing , Li Xingda 
Published: August 2024

It is the magnetic field topography that determines the ion thruster discharge performance. A three-dimension numerical model of the 20 cm ion thruster discharge chamber was established, and a particle-in-cell method was used to model the discharge process to investigate the effect of the magnetic field topography on the ionization rate and plasma distribution. The results showed that compared with the cylindrical-cusp magnetic field topography, the ring-cusp field made the energetic electrons primarily confined for their increased path length prior to loss to the anode wall and caused the ionization rate to be increased, but the plasma distributed uniformly upstream of the screen grid and the beam flatness was compared to be decreased to 14.8%. When the magnet size was increased and the distance between magnets was changed, the magnetic field contour and the magnetic flux density were modified, and then an improved beam flatness was obtained, from 0.556 to 0.658, by 15.5%.
On the topological number in Kelvin’s circulation of inviscid fluids
Authors: Guo Z B 
Published: August 2024

Abstract
Kelvin’s circulation, as a loop integral of the velocity field, is first shown to be equal to

Γ

C

=
2
π
Δ
n

Γ

1

+
constant

in an inviscid fluid, with Γ1 a unit circulation. The integer Δn is interpreted as the number of net 2π-rotations of the velocity vector in one cyclicality along the circulation loop and hence it is a topological number. Different from the linkage number in the helicity invariant, which only exists in 3D space, the topological number in the circulation invariant is independent of the spatial dimension. A further study reveals that this new topological phase 2πΔn is rooted at the gauge invariance of the circulation and it is a counterpart of the Berry’s phase in the quantum system.
Quantum tomography of a photon-number-resolving detector based on continuous time multiplexing: memory effect
Authors: Avosopiants G V , Katamadze K G , Borshchevskaia N A , Bogdanov Yu I , Kulik S P 
Published: August 2024

AbstractWe address the characterization of a photon-number-resolving detector based on continuous time multiplexing. We develop and verify a mathematical model of this detector and explore various approaches to its quantum tomography. Additionally, we encounter a memory effect and discuss the feasibility of describing this type of detector using a transfer matrix or positive operator-valued measure (POVM) decomposition.
Structural design and analysis of multi-rotor UAV
Authors: Zhang Liangyang , Xi Chao , Li Yihai , Chen Li 
Published: August 2024

Abstract
As an important aircraft branch, multi-rotor UAV is widely used in civil and military fields. In this paper, the overall scheme design of a multi-rotor UAV is proposed and the structural design flow and analysis and calculation process are introduced in detail. With the help of three-dimensional modeling software, the body structure of the multi-rotor UAV is obtained, and the relevant design parameters are determined. In addition, ANSYS software is used for structural finite element analysis, and the strength and stiffness of the body structure are analyzed according to different flight conditions. The analysis results show that the design is reasonable and meets the use requirements, which guides further research.
Deformation control and weight optimization of civil aircraft nose structures
Authors: Zhao Enkang , Yuan Xinhao 
Published: August 2024

Abstract
The airtight load is one of the main loads on civil aircraft fuselage, and the fuselage cross-section will tend to deform in a positive circle under the effect of the airtight load. Deformation varies for structures with different contour curvatures for the same airtight load and structural stiffness, especially in the contraction section of the fuselage. Therefore, the deformation of the structure can be controlled by optimizing the contour curvature without increasing the structure stiffness, resulting in a lighter overall weight for the same deformation, thus achieving weight reduction. In a civil aircraft concept design phase, structural deformation control was carried out by optimizing the nose contour, and the results showed that a structural weight reduction of approximately 4% was achieved with a maximum reduction of 23% in structural deformation.
Aerodynamic shape optimization of aft propulsive fuselage concept using an internal/external integration model
Authors: Liu Xingjian , Lu Yujiang , Wang Xuelin , Zhang Zhihua , Jiang Chen 
Published: August 2024

Abstract
The new turboelectric aircraft with aft propulsion fuselage concept (APFC) utilizes an electrically driven fan powered by main engines that ingest the fuselage boundary layer for increased propulsive efficiency. However, with the high integration of the fuselage and the aft propulsion system, the APFC produces the coupling problem of the internal/external flow field. In this paper, an integration model using computational fluid dynamics (CFD)-based aerodynamic shape optimization is performed to study the power savings of the APFC to a reference traditional podded configuration. The results show that the power savings of APFC have a better performance compared to a traditional propulsion system.
Impact analysis of design parameters and flow mechanism of ducted fan
Authors: Liu Yulu , Li Weipeng 
Published: August 2024

Abstract
The ducted fan has become one of the most promising electric propulsion devices for aviation electrification due to its high aerodynamic efficiency, excellent safety, and low aerodynamic noise. An accurate numerical calculation method for electrically driven ducted fans is established based on the Reynolds-averaged Navier-Stokes equation (RANS) and the multiple reference frame (MRF) method, with validation of the computational results against NASA’s wind tunnel test for ducted fans. Based on the method, the effects of duct lip shape, tip clearance, and inflow velocity on the aerodynamic performance of the ducted fan, as well as the intrinsic mechanism, are investigated. The result shows that the curvature of the duct lip and the vertex position jointly affect the negative pressure area, thus affecting the additional thrust of the duct; the increasing tip clearance weakens the inhibitory effect on the tip vortex, leading to decreased aerodynamic efficiency. The thrust contribution of the duct in the cruise state is significantly lower compared to the hover state. As the inflow velocity increases, the thrust of the ducted fan decreases, while the propulsion efficiency first increases and then decreases.
Performance analysis of CAT III autoland systerm under steady wind interference
Authors: Yang Jianzhong , Hao Yanan , Yang Shibin 
Published: August 2024

Abstract
In view of the certification for the CAT III autoland of Civil aircraft, an analysis method based on Monte Carlo simulation is proposed. First of all, the performance requirements of CAT III autoland of Civil aircraft are analyzed, and then the autoland model of aircraft with six degrees of freedom is established, and the guidance law, autoland control law and steady wind random model are designed, and then the quantitative analysis of the touchdown point, touchdown attitude angle and vertical speed are carried out by Monte Carlo random simulation. The simulation results show that the autoland system satisfy the CAT III Autoland design requirements under steady wind interference, and recognize the factors that have a great influence on the automatic landing performance and the limitations of the CAT III autoland system through Monte Carlo simulation, which provides reference for the subsequent airworthiness compliance verification of civil aircraft.
Numerical study on the duty cycle of a pulsed jet in the combustion flow field
Authors: Wang Yuhan 
Published: August 2024

Abstract
The study of steady fuel injection schemes is becoming more and more mature and has been widely used in the combustion chamber, while the time effect of fuel injection is also worth studying. This paper discusses the effect of pulse jets with different duty cycles on the combustion efficiency of hydrogen gas using the same jet parameters. The combustion flow fields are calculated with Reynold-averaged multi-component N-S equations, based on the finite volume method. The result shows that when the duty cycle is increased, the hydrogen mass flow rate increases, the impulse interference is enhanced, the amount of hydrogen combusted increases, and the total pressure recovery coefficient decreases, which is still larger than the steady jet. At the duty cycle of 0.75, the amount of hydrogen combusted increases by about 14% compared to the steady jet. When the duty cycle is 0.25, the total pressure recovery coefficient of the exit section of the combustion chamber increases by about 9.2% compared with the steady jet.
Disturbance observer-based attitude control for flight vehicle under actuators output deviation disturbance and sensor noise
Authors: Zhang Dafa , Meng Wengong , Gao Xuegang , Zhu Qian , Chai Dingyu , Ma Pengbao , Cui Qiang 
Published: August 2024

Abstract
This paper investigates the problem of attitude stabilization control for flight vehicle subject to actuators output deviation disturbance and sensor noise. Firstly, a full order observer is designed which gives an estimation of system state and external disturbances. Furthermore, to ensure attitude error converging to zero, an attitude stabilization control law which is based on output-feedback method is developed. Finally, numerical simulation and semi-physical simulation results are given to demonstrate the effectiveness of proposed attitude stabilization control law.
Design and mechanism research of extremely strong anti-corrosion coatings with rapid self-healing capability
Authors: Jiang H , Cheng M , Li C , Sun S Q , Hu S 
Published: August 2024

Abstract
Organic coatings possess great anti-corrosion properties, but they cannot repair themselves after being damaged and thus losing their protective ability. In this article, we designed a new coating capable of self-healing and superior anti-corrosion properties. In the molecular structure, the existence of abundant hydrogen bonds and N elements endows the coating excellent adhesion strength (8.36 MPa) and anti-corrosion property. The dynamic rearrangement of the numerous hydrogen bonds after being damaged can also promotes the self-healing process. After self-healing at 60 °C for 3 h, the toughness of the coating can recover by 89.3% and the anti-corrosion performance is also similar to the original sample. Besides we also performed the self-healing mechanism analysis combining the molecular dynamics (MD) simulations and experimental methods. According to the change of vdW energy and the number of hydrogen bonds analysis during the self-healing process, the recombination of hydrogen bonds and (van der Waals) vdW interactions promote self-healing. This work offers a valuable strategy for engineering protective coatings that possess both efficient self-healing capabilities and sensitive corrosion reporting functions and a feasible method to perform the mechanism analysis.