bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Role of Public Knowledge, Resources, and Innovation in Responding to the Ebola Outbreak
Authors: Goldstone Brian J. , Brown Brandon 
Published: April 2015

AbstractSince the beginning of the recent Ebola outbreak, a sense of fear has developed among the public due to the novelty of our exposure to the virus and the ill-equipped nature of our health care systems. Media sensationalism, coupled with improper knowledge of Ebola, may have contributed to mass hysteria. Most support to tackle Ebola has been direct monetary aid. However, others are working on innovative methods to control the epidemic, including the development of rapid detection methods, experimental treatments, and a viable vaccine. Rapid screening and vaccine ideas are promising, but it is unlikely that they will be ready in the coming months. This raises the question of what other tools and technological innovation can be developed to effectively stem the spread of the outbreak. Although we hope the continued outpouring of aid and health care workers to West Africa will greatly reduce the impact of Ebola, communication, screenings, treatment, and vaccine are of central importance to stop this outbreak. (Disaster Med Public Health Preparedness. 2015;9:595–597)
Stabilization of a high-order harmonic generation seeded extreme ultraviolet free electron laser by time-synchronization control with electro-optic sampling
Authors: Tomizawa H. , Sato T. , Ogawa K. , Togawa K. , Tanaka T. , Hara T. , Yabashi M. , Tanaka H. , Ishikawa T. , Togashi T. , Matsubara S. , Okayasu Y. , Watanabe T. , Takahashi E.J. , Midorikawa K. , Aoyama M. , Yamakawa K. , Owada S. , Iwasaki A. , Yamanouchi K. 
Published: April 2015

A fully coherent free electron laser (FEL) seeded with a higher-order harmonic (HH) pulse from high-order harmonic generation (HHG) is successfully operated for a sufficiently prolonged time in pilot user experiments by using a timing drift feedback. For HHG-seeded FELs, the seeding laser pulses have to be synchronized with electron bunches. Despite seeded FELs being non-chaotic light sources in principle, external laser-seeded FELs are often unstable in practice because of a timing jitter and a drift between the seeding laser pulses and the accelerated electron bunches. Accordingly, we constructed a relative arrival-timing monitor based on non-invasive electro-optic sampling (EOS). The EOS monitor made uninterrupted shot-to-shot monitoring possible even during the seeded FEL operation. The EOS system was then used for arrival-timing feedback with an adjustability of 100 fs for continual operation of the HHG-seeded FEL. Using the EOS-based beam drift controlling system, the HHG-seeded FEL was operated over half a day with an effective hit rate of 20%–30%. The output pulse energy was

$20~{\rm\mu}\text{J}$

at the 61.2 nm wavelength. Towards seeded FELs in the water window region, we investigated our upgrade plan to seed high-power FELs with HH photon energy of 30–100 eV and lase at shorter wavelengths of up to 2 nm through high-gain harmonic generation (HGHG) at the energy-upgraded SPring-8 Compact SASE Source (SCSS) accelerator. We studied a benefit as well as the feasibility of the next HHG-seeded FEL machine with single-stage HGHG with tunability of a lasing wavelength.
Outbreak of Clostridium difficile Infections at an Outpatient Hemodialysis Facility—Michigan, 2012–2013
Authors: See Isaac , Bagchi Suparna , Booth Stephanie , Scholz Daniel , Geller Andrew I. , Anderson Lydia , Moulton-Meissner Heather , Finks Jennie L. , Kelley Karen , Gould Carolyn V. , Patel Priti R. 
Published: April 2015

Investigation of an outbreak of Clostridium difficile infection (CDI) at a hemodialysis facility revealed evidence that limited intrafacility transmission occurred despite adherence to published infection control standards for dialysis clinics. Outpatient dialysis facilities should consider CDI prevention, including environmental disinfection for C. difficile, when formulating their infection control plans.Infect. Control Hosp. Epidemiol. 2015;36(8):972–974
The Impact of Discontinuing Contact Precautions for VRE and MRSA on Device-Associated Infections
Authors: Edmond Michael B. , Masroor Nadia , Stevens Michael P. , Ober Janis , Bearman Gonzalo 
Published: April 2015

The impact of discontinuing contact precautions for patients with MRSA and VRE colonization/infection on device-associated hospital-acquired infection rates at an academic medical center was investigated in this before-and-after study. In the setting of a strong horizontal infection prevention platform, discontinuation of contact precautions had no impact on device-associated hospital-acquired infection rates.Infect. Control Hosp. Epidemiol. 2015;36(8):978–980
SAPPING THE NARRATIVE: IBN KATHIR’S ACCOUNT OF THESHŪRĀOF ʿUTHMAN INKITAB AL-BIDAYA WA-L-NIHAYA
Authors: Hagler Aaron M. 
Published: April 2015

AbstractOne mission of Ibn Kathir'sKitab al-Bidaya wa-l-Nihaya fi al-Taʾrikh(The Book of the Beginning and the End in History) is to provide a Sunni answer to a generally ʿAlid-legitimizing corpus of early Islamic historical accounts. Part of the 13th- and 14th-century movement that sought to rehabilitate the image of Syria and the otherwise reviled Umayyad dynasty (r. 661–750), Ibn Kathir's grand work of history cleverly reframes the early Islamic narrative to fit into what he considers a more “properly” Sunni framework than his sources provided. This article focuses on Ibn Kathir's presentation of theshūrā, the council appointed by ʿUmar and charged with choosing from among its six members his successor. It identifies the literary tools Ibn Kathir employed and offers a framework for his strategy of employing them. Whether through narrative aside or criticism of other historians, Ibn Kathir's recasting of a pro-ʿAlid grudge story as an Umayyad apologetic highlights moments of sectarian contention and emphasizes the evolution of Sunni opinion on ʿAli and ʿUthman.
An assessment of the effects of fertilizer nitrogen management on nitrate leaching risk from grazed dairy pasture
Authors: VOGELER I. , LUCCI G. , SHEPHERD M. 
Published: April 2015

SUMMARYDairy farms are under pressure to increase productivity while reducing environmental impacts. Effective fertilizer management practices are critical to achieve this. In the present study the effect of timing and rate of nitrogen (N) fertilizer application on pasture production and N losses, either via direct leaching of fertilizer N or indirectly through consumption of N in pasture and subsequent excretion via dairy cow grazing, was modelled. The Agricultural Production Systems Simulator (APSIM) was first tested with experimental data from N fertilizer response experiments conducted on a well-drained soil in the Waikato region of New Zealand. The model was then used in a 20-year simulation to investigate the effect of fertilizer management on the impacts on potential N leaching losses. Year-to-year variability was assessed by incorporating 20 years of climate data into the model. Modelling indicated that N fertilization at rates of 140 and 220 kg N/ha/year, applied in four split applications and avoiding application in winter months, could increase pasture yield on average by 2·2–3·0 t dry matter (DM)/ha (25–38%). There were some significant amounts of direct leaching in some years, related to environmental conditions. The maximum loss was as high as 61 kg N/ha at an N application rate of 220 kg N/ha/year, in a year with low pasture production and high rainfall following fertilizer application. In general, however, the risk of direct N leaching from applied fertilizer was low. It seems the main effect of N fertilization is to increase the risk of indirect N leaching, due to increased N intake and excretion. The modelling indicated that the major contribution to increased indirect N leaching risk was from the extra DM grown (more urine deposited per ha). Increased N concentration in the pasture due to fertilization and the resultant extra partitioning of excretal N to urine had only a minor effect on indirect leaching losses. The exception was N fertilizer applied in late winter/early spring (July), where fertilizer N (55 kg/ha) increased pasture N concentration byc. 25%, suggesting that the N concentration in urine patch areas could increase fromc. 550 to 840 kg N/ha. Further measurements are required to test the hypothesis developed from the modelling that the main effect of N fertilizer on urinary N leaching is by increasing DM production rather than increasing pasture N concentration.
The economic origins of ultrasociality
Authors: Gowdy John , Krall Lisi 
Published: April 2015

AbstractUltrasociality refers to the social organization of a few species, including humans and some social insects, having a complex division of labor, city-states, and an almost exclusive dependence on agriculture for subsistence. We argue that the driving forces in the evolution of these ultrasocial societies were economic. With the agricultural transition, species could directly produce their own food and this was such a competitive advantage that those species now dominate the planet. Once underway, this transition was propelled by the selection of within-species groups that could best capture the advantages of (1) actively managing the inputs to food production, (2) a more complex division of labor, and (3) increasing returns to larger scale and larger group size. Together these factors reoriented productive life and radically altered the structure of these societies. Once agriculture began, populations expanded as these economic drivers opened up new opportunities for the exploitation of resources and the active management of inputs to food production. With intensified group-level competition, larger populations and intensive resource exploitation became competitive advantages, and the “social conquest of Earth” was underway. Ultrasocial species came to dominate the earth's ecosystems. Ultrasociality also brought a loss of autonomy for individuals within the group. We argue that exploring the common causes and consequences of ultrasociality in humans and the social insects that adopted agriculture can provide fruitful insights into the evolution of complex human society.
EMPLEO Y CARRERAS LABORALES EN CORREOS DE ESPAÑA, 1890-1935
Authors: Domenech Jordi 
Published: April 2015

ABSTRACTThe development of postal services has played an indisputable role in industrialization, market integration and state formation. Smooth functioning of these services depended on the existence of a well-paid and motivated body of civil servants. I study the organization of the internal labour market for civil servants in postal services in Spain from 1890 to 1935 showing a career in the postal services offered high entry wages, growing wages over the life cycle, and a secure job until retirement. There were two downsides to pursuing a career in the postal services. Firstly, entry and promotion depended on the expansion of employment. Secondly, nominal wages were upward rigid, causing large real wage losses during WWI.
High-charge divergent electron beam generation from high-intensity laser interaction with a gas-cluster target
Authors: Koester P. , Bussolino G.C. , Cristoforetti G. , Faenov A. , Giulietti A. , Giulietti D. , Labate L. , Levato T. , Pikuz T. , Gizzi L.A. 
Published: April 2015

AbstractWe report on an experimental study on the interaction of a high-contrast 40 fs duration 2 TW laser pulse with an argon-cluster target. A high-charge, homogeneous, large divergence electron beam with moderate kinetic energy (~2 MeV) is observed in the forward direction. The results show that an electron beam with a charge as high as 12 nC can be obtained using a table-top laser system. It was demonstrated that the accelerated electron beam is suitable for a variety of applications such as micro-radiography of thin samples in a wide field of view. It can also be applied forin vitrodosimetry studies.
Using analogies to explain versus inspire concepts
Authors: Chou Amanda , Shu L.H. 
Published: April 2015

AbstractWe aim to examine the potential of using analogies in design education and to compare the roles of analogies in explaining versus inspiring in engineering design. We review existing research in analogical thinking, with a focus on scientific discourse and education. Then we explore the role of analogies in design education in making concepts more relatable by asking six participants in a graduate-level design course to generate analogies for course topics. We describe criteria developed to evaluate the analogies and present these evaluations. We then asked participants to perform divergent thinking tests, but we found no significant correlation between these and analogy scores. The participants were also asked to reflect on what constitutes an effective analog, describe their process of identifying analogies, and provide their definitions of analogies. We describe possible links between these comments and the ratings of their analogies. We then draw on results in using analogies in pedagogy to inform and reflect on obstacles we encountered in the use of analogies to inspire. Specifically, we related them to our experience with biomimetic or biologically inspired design, where we used a natural-language search approach to identify relevant analogies. Three aspects discussed are familiarity of source analogies, boundaries of parallels between source analogies and target concepts, and concreteness of source analogies. Finally, we discuss possible pedagogical benefits of eliciting analogies on course topics from students, namely, using the elicited analogies as tools for improved student engagement as well as more prompt instructor feedback.
How do analogizing and mental simulation influence team dynamics in innovative product design?
Authors: Casakin Hernan , Ball Linden J. , Christensen Bo T. , Badke-Schaub Petra 
Published: April 2015

AbstractThe aim of this study was to gain further insight into how analogical reasoning and mental simulation, two cognitive strategies, influence team dynamics in innovative product design. A particular emphasis was placed on exploring the association between these two strategies and team cohesion and team collaboration. Analogies were coded for “analogical distance” (i.e., within domain or between domain) and “analogical purpose” (i.e., problem identification, function finding, solution generation, and explanation). The results indicated that the presence of either analogizing or mental simulation was related to team cohesion and team collaboration, with mental simulation having an especially marked association with team collaboration. Within-domain analogizing was found to enhance team collaboration, but it did not influence team cohesion. Furthermore, all types of analogical purpose showed a similar association with team cohesion, whereas solution generation and function finding had a stronger association with team collaboration. We propose that analogizing and mental simulations are strategies that serve valuable functions in engendering enhanced cohesion and collaboration, which might be expected to lead to more effective design outcomes, although this remains an empirical question in need of further corroboration.
On the benefits of digital libraries of case studies of analogical design: Documentation, access, analysis, and learning
Authors: Goel Ashok K. , Zhang Gongbo , Wiltgen Bryan , Zhang Yuqi , Vattam Swaroop , Yen Jeannette 
Published: April 2015

AbstractDigital libraries of case studies of analogical design have been popular since their advent in the early 1990s. We consider four benefits of digital libraries of case studies of analogical design in the context of biologically inspired design. First, a digital library affords documentation. The 83 case studies in our work come from 8 years of extended, collaborative design projects in an interdisciplinary class on biologically inspired design. Second, a digital library provides on-demand access to the case studies. We describe a web-based library of case studies of biologically inspired design called the Design Study Library (DSL). Third, a compilation of case studies supports analyses of broader patterns and trends. As an example, an analysis of DSL's case studies found that environmental sustainability was a major factor in about a third of the case studies and an explicit design goal in about a fourth. Fourth, a digital library of case studies can support analogical learning. Preliminary results from an exploratory study indicate that DSL may support novice learning about the processes of biologically inspired design.
Intakes of apple juice, fruit drinks and soda are associated with prevalent asthma in US children aged 2–9 years
Authors: DeChristopher Luanne Robalo , Uribarri Jaime , Tucker Katherine L 
Published: April 2015

AbstractObjectiveHigh soft drink consumption has been linked with asthma. Anecdotal evidence links high-fructose corn syrup with asthma. The receptor of advanced glycation end products (RAGE) has emerged as a mediator of asthma. The objectives of the present study were to: (i) assess the correlation between intake of beverages containing excess free fructose (EFF beverages) and asthma in children; and (ii) epidemiologically test the mechanistic hypothesis that intake of high EFF beverages, such as apple juice or beverages sweetened with high-fructose corn syrup, is associated with increased risk of asthma. This hypothesis is based on the possible effect of increases in the in situ intestinal formation of advanced glycation end products (enFruAGE) with EFF, which may be absorbed and play a role in RAGE-mediated asthma.DesignWe examined cross-sectional associations between beverage intake and self-reported current or history of asthma. Exposure variables were EFF beverages, including apple juice (AJ), non-diet soft drinks (ndSD) and fruit drinks (FD). Orange juice (OJ), not an EFF beverage, was included as a comparison. Rao–Scott χ2 analysis was used for prevalence differences and logistic regression for associations, adjusted for age, sex, race/ethnicity, BMI and total energy intake.SettingData are from the National Health and Nutrition Examination Survey 2003–2006, a nationally representative survey.SubjectsUS children (n 1961) aged 2–9 years with complete responses on the dietary frequency questionnaire.ResultsIntakes of EFF beverages were significantly associated with asthma in 2–9-year-olds. Adjusted odds of asthma in children consuming EFF beverages ≥5 times/week was more than five times that in children consuming these beverages ≤1 time/month (OR=5·29, P=0·012). Children consuming AJ ≥5 times/week v. ≤1 time/month, adjusted for the other beverages, were more than twice as likely to have asthma (OR=2·43, P=0·035). In contrast, there was a tendency for OJ to be protective.ConclusionsThese results support the hypothesis that intake of high EFF beverages, including AJ and beverages sweetened with high-fructose corn syrup, is associated with asthma in children aged 2–9 years. Results support the mechanistic hypothesis that enFruAGE may be an overlooked contributor to asthma in children. Longitudinal studies are needed to provide evidence of causal association.
Revealing the role of organic cations in hybrid halide perovskite CH3NH3PbI3
Authors: Motta Carlo , El-Mellouhi Fedwa , Kais Sabre , Tabet Nouar , Alharbi Fahhad , Sanvito Stefano 
Published: April 2015

AbstractThe hybrid halide perovskite CH3NH3PbI3 has enabled solar cells to reach an efficiency of about 20%, demonstrating a pace for improvements with no precedents in the solar energy arena. Despite such explosive progress, the microscopic origin behind the success of such material is still debated, with the role played by the organic cations in the light-harvesting process remaining unclear. Here van der Waals-corrected density functional theory calculations reveal that the orientation of the organic molecules plays a fundamental role in determining the material electronic properties. For instance, if CH3NH3 orients along a (011)-like direction, the PbI6 octahedral cage will distort and the bandgap will become indirect. Our results suggest that molecular rotations, with the consequent dynamical change of the band structure, might be at the origin of the slow carrier recombination and the superior conversion efficiency of CH3NH3PbI3.
Role of the endocannabinoid system in obesity induced by neuropeptide Y overexpression in noradrenergic neurons
Authors: Vähätalo L H , Ruohonen S T , Mäkelä S , Ailanen L , Penttinen A-M , Stormi T , Kauko T , Piscitelli F , Silvestri C , Savontaus E , Di Marzo V 
Published: April 2015

Abstract
Objective:
Endocannabinoids and neuropeptide Y (NPY) promote energy storage via central and peripheral mechanisms. In the hypothalamus, the two systems were suggested to interact. To investigate such interplay also in non-hypothalamic tissues, we evaluated endocannabinoid levels in obese OE-NPYDβH mice, which overexpress NPY in the noradrenergic neurons in the sympathetic nervous system and the brain.

Methods:
The levels of the endocannabinoids anandamide and 2-arachidonoylglycerol (2-AG) were measured in key regulatory tissues, that is, hypothalamus, pancreas, epididymal white adipose tissue (WAT), liver and soleus muscle, over the development of metabolic dysfunctions in OE-NPYDβH mice. The effects of a 5-week treatment with the CB1 receptor inverse agonist AM251 on adiposity and glucose metabolism were studied.

Results:
2-AG levels were increased in the hypothalamus and epididymal WAT of pre-obese and obese OE-NPYDβH mice. Anandamide levels in adipose tissue and pancreas were increased at 4 months concomitantly with higher fat mass and impaired glucose tolerance. CB1 receptor blockage reduced body weight gain and glucose intolerance in OE-NPYDβH to the level of vehicle-treated wild-type mice.

Conclusions:
Altered endocannabinoid tone may underlie some of the metabolic dysfunctions in OE-NPYDβH mice, which can be attenuated with CB1 inverse agonism suggesting interactions between endocannabinoids and NPY also in the periphery. CB1 receptors may offer a target for the pharmacological treatment of the metabolic syndrome with altered NPY levels.