bluuebunny/crossref_metadata_2025_split huggingface dataset:
Storage, properties and seasonal variations in fine‐grained bed sediment within the main channel and headwaters of the River Sanginjoki, Finland
Authors: Marttila H. , Kløve B. 
Published: July 2013

AbstractLowland catchments in Finland are intensively managed, promoting erosion and sedimentation that negatively affects aquatic environments. This study quantified fine‐grained bed sediment in the main channel and upstream headwaters of the River Sanginjoki (399.93 km2) catchment, Northern Finland, using remobilization sediment sampling during the ice‐free period (May 2010–December 2011). Average bed sediment storage in river was 1332 g m−2. Storage and seasonal variations were greater in small headwater areas (total bed sediment storage mean 1527 g m−2, range 122–6700 g m−2 at individual sites; storage of organic sediment: mean 414 g m−2, range 27–3159 g m−2) than in the main channel (total bed sediment storage: mean 1137 g m−2, range 61–4945 g m−2); storage of organic sediment: mean 329 g m−2, range 13–1938 g m−2). Average reach‐specific bed sediment storage increased from downstream to upstream tributaries. In main channel reaches, mean specific storage was 8.73 t km−1, and mean specific storage of organic sediment 2.45 t km−1, whereas in tributaries, it was 126.94 and 34.05 t km−1, respectively. Total fine‐grained bed sediment storage averaged 563 t in the main channel and 6831 t in the catchment. The proportion of mean organic matter at individual sites was 15–47% and organic carbon 4–455 g C m−2, with both being highest in small headwater tributaries. Main channel bed sediment storage comprised 52% of mean annual suspended sediment flux and stored organic carbon comprised 7% of mean annual total organic carbon load. This indicates the importance of small headwater brooks for temporary within‐catchment storage of bed sediment and organic carbon and the significance of fine‐grained sediment stored in channels for the suspended sediment budget of boreal lowland rivers. Copyright © 2013 John Wiley & Sons, Ltd.
Cell death in the myocardium: My heart won't go on
Authors: Orogo Amabel M. , Gustafsson Åsa B. 
Published: July 2013

AbstractLoss of cardiomyocytes plays a critical role in the pathogenesis of heart failure. With fewer myocytes, the heart is unable to sustain efficient contraction. Much attention has been focused on understanding mechanisms of cell death in myocytes with the ultimate goal being to reduce the extent of injury and improve function in the failing myocardium. Both necrosis and apoptosis contribute to loss of myocytes, and this loss of cells is a hallmark of cardiac pathologies, including ischemia/reperfusion, myocardial infarction, and heart failure. Apoptosis is a highly regulated process that is activated via death receptors in the plasma membrane or via permeabilization of the mitochondria. Necrosis is generally viewed as an uncontrolled process that leads to mitochondrial swelling, cell rupture, and subsequent inflammation. However, recent studies have uncovered a signaling pathway that mediates regulated necrosis or necroptosis. Mitochondria play an important role in both apoptosis and necrosis, and changes in their morphology can affect the cells' susceptibility to stress. This review focuses on the various modes of cell death in the myocardium and highlights how they contribute to loss of myocytes in response to stress. © 2013 IUBMB Life, 65(8):651–656, 2013
When the wind goes out of the sail – declining recovery expectations in the first weeks of back pain
Authors: Carstens J.K.P. , Shaw W.S. , Boersma K. , Reme S.E. , Pransky G. , Linton S.J. 
Published: July 2013

AbstractBackgroundExpectations for recovery are a known predictor for returning to work. Most studies seem to conclude that the higher the expectancy the better the outcome. However, the development of expectations over time is rarely researched and experimental studies show that realistic expectations rather than high expectancies are the most adaptive. This study aims to explore patterns of stability and change in expectations for recovery during the first weeks of a back‐pain episode and how these patterns relate to other psychological variables and outcome.MethodsThe study included 496 volunteer patients seeking treatment for work‐related, acute back pain. The participants were measured with self‐report scales of depression, fear of pain, life impact of pain, catastrophizing and expectations for recovery at two time points. A follow‐up focusing on recovery and return to work was conducted 3 months later. A cluster analysis was conducted, categorizing the data on the trajectories of recovery expectations.ResultsCluster analysis revealed four clusters regarding the development of expectations for recovery during a 2‐week period after pain onset. Three out of four clusters showed stability in their expectations as well as corresponding levels of proximal psychological factors. The fourth cluster showed increases in distress and a decrease in expectations for recovery. This cluster also has poor odds ratios for returning to work and recovery.ConclusionDecreases in expectancies for recovery seem as important as baseline values in terms of outcome, which has clinical and theoretical implications.
Solar magnetic polarity dependency of the cosmic ray diurnal variation
Authors: Sabbah I. 
Published: July 2013

AbstractCosmic rays (CRs) data observed through four neutron monitors and one muon telescope are used to study the solar diurnal variation (DV) from 1953 to 2010. The median primary rigidity of response, (Rm), for these detectors encompasses the range 16 ≤ Rm ≤ 60 GV of the galactic CRs spectrum. The phase angle observed with the lower rigidity station depends strongly on the solar magnetic field polarity reversal due to drift effect. However, the higher rigidity stations show an 11 year cycle. This cycle is evident in the shape of the cross‐correlation functions (CCFs) between the phase angle and the interplanetary magnetic field (IMF) parameters due to diffusion of galactic CRs by the IMF. The amplitude of the DV, IMF magnitude, and solar activity are larger, and the phase angle is later in hours for qA < 0 than for qA > 0. In addition, the amplitude is well correlated with the IMF magnitude. The amplitudes observed by the lower rigidity station peaks 2 years after the IMF magnitude reach maximum for qA < 0. The diurnal amplitude reaches minimum 2–3 years after the solar wind speed peak due to outward convection by solar wind along the helioequator. The phase angle of the higher rigidity station shifts toward the earliest hours, 2 years after the wind speed peaks for qA > 0. This shift is due to outward convection by solar wind that increases the radial component of the DV more than the East‐West component.
Characterization and indexing of heavy rainstorms in Hong Kong
Authors: Wu Manchi , Lam Hilda , Li Kinwai 
Published: July 2013

ABSTRACTHeavy rain events or rainstorms of various scales often occur in Hong Kong from April to September. In extremes cases, they lead to serious landslides and flash floods resulting in loss of life, and damage to property and infrastructure. With climate change, extreme rain events are projected to be more frequent and more intense in this region. A system to gauge and label the severity of rainstorms would be useful for identifying and communicating extreme conditions in warning and disaster prevention operations. In parallel, a better understanding of the characteristics of rainstorms would also be important for impact assessments and engineering design purposes. This paper formulates a practical framework to index the magnitude and severity of rainstorms in Hong Kong. An index termed as the Severity Index combining the magnitude of different rainstorm attributes is devised for quantifying the overall severity of rainstorms. This index is flexible to allow tuning for specific applications.
Mixed boundary value problems of diffraction by a half‐plane with an obstacle perpendicular to the boundary
Authors: Castro Luis P. , Kapanadze David 
Published: July 2013

AbstractThe paper is devoted to the analysis of wave diffraction problems modeled by classes of mixed boundary conditions and the Helmholtz equation, within a half‐plane with a crack. Potential theory together with Fredholm theory, and explicit operator relations, are conveniently implemented to perform the analysis of the problems. In particular, an interplay between Wiener–Hopf plus/minus Hankel operators and Wiener–Hopf operators assumes a relevant preponderance in the final results. As main conclusions, this study reveals conditions for the well‐posedness of the corresponding boundary value problems in certain Sobolev spaces and equivalent reduction to systems of Wiener–Hopf equations. Copyright © 2013 John Wiley & Sons, Ltd.
Single bend paths on a grid have strong helly number 4: errata atque emendationes ad “edge intersection graphs of single bend paths on a grid”
Authors: Golumbic Martin Charles , Lipshteyn Marina , Stern Michal 
Published: July 2013

AbstractIn this note, we prove that a collection of single bend paths on a grid, the so‐called B1 representations, have strong Helly number 4. This corrects a false claim from Ref. [Golumbic et al., Networks, 54 (2009), 130–138; and other errata are also corrected. © 2013 Wiley Periodicals, Inc. NETWORKS, 2013
Quam bene vivas referre: curing and caring in psycho‐oncology
Authors: Grassi Luigi 
Published: July 2013

AbstractBackgroundBy examining the medical–philosophical Latin heritage, some psycho‐oncology principles may be traced in Claudius Galenus and Lucius Anneus Seneca. The former hypothesized a link between depression and cancer; the latter strongly underlined the need for not wasting time, living in the present by searching for meaning and reaching well‐being of the soul through virtues, even when dealing with misfortune and negative life events.MethodsOn these premises, what follows here is an analysis of the first steps in the science of psychosocial care in cancer starting with the work of Arthur M. Sutherland and moving on to more recent psycho‐oncology research, which has shown the centrality of a biopsychosocial approach in cancer integrating cure and care (within the double meaning of the old Latin noun cura).ResultsStudies of the biopsychosocial approach covering the psychological implications of cancer (e.g., prevalence of emotional distress, application of DSM/ICD classical, and more recent psychiatric classification systems), their psychobiological concomitants (e.g., inflammation and immune dysregulation mechanisms in depression and chronobiology of stress and cancer), and interpersonal issues (e.g., doctor–patient communication and role of neuron mirror system) are discussed.ConclusionsPsychosocial oncology avoids the distinction between curing and caring and includes science and compassion in a whole approach to the multidimensionality of the human being in balancing evidence‐based with person‐centered/narrative‐based oncology (values‐based oncology). Copyright © 2013 John Wiley & Sons, Ltd.
Psychosocial screening effects on health‐related outcomes in patients receiving radiotherapy. A cluster randomised controlled trial
Authors: Braeken Anna P. B. M. , Kempen Gertrudis I. J. M. , Eekers Daniëlle B. P , Houben Ruud M. A. , van Gils Francis C. J. M. , Ambergen Ton , Lechner Lilian 
Published: July 2013

AbstractObjectiveThis study examined the short‐term and long‐term effects of using a screening instrument on psychological distress and health‐related quality of life (HRQoL) among cancer patients receiving radiotherapy. In addition, we investigated the effect of early psychosocial treatment on patients' overall health‐related outcomes as previous research showed that patients in the screening condition were referred to a psychosocial caregiver at an earlier stage.MethodsA cluster randomised controlled trial with a randomisation at the levels of 14 radiotherapists, 568 patients was conducted. Patients were asked to complete questionnaires at 3 and 12 months follow‐up.ResultsMixed models analyses showed no significant intervention effects on patients' overall extent of psychosocial distress and HRQoL, both on the short and long terms. Post‐hoc analyses revealed significant interactions of the intervention with early referral and improved HRQoL and anxiety, suggesting that earlier referral might influence short‐term HRQoL and experienced anxiety in patients.ConclusionsOur results suggest that the use of a psychosocial screening instrument among patients receiving radiotherapy in itself does not sufficiently improve patients' health‐related outcome. The effective delivery of psychosocial care depends upon several components such as identification of distress and successful implementation of screening procedures. One of the challenges is to get insight in the effects of early referral of cancer patients for psychosocial support because early referral might have a favourable effect on some of the patients' health‐related outcomes. Copyright © 2013 John Wiley & Sons, Ltd.
Breast cancer screening utilization among Eastern European immigrant women worldwide: a systematic literature review and a focus on psychosocial barriers
Authors: Andreeva Valentina A. , Pokhrel Pallav 
Published: July 2013

AbstractObjectiveMany countries host growing Eastern European immigrant communities whose breast cancer preventive behaviors are largely unknown. Thus, we aimed to synthesize current evidence regarding secondary prevention via breast cancer screening utilized by that population.MethodsAll observational, general population studies on breast cancer screening with Eastern European immigrant women and without any country, language, or age restrictions were identified. Screening modalities included breast self‐examination, clinical breast examination, and mammography.ResultsThe selected 30 studies were published between 1996 and 2013 and came from Australia, Canada, Denmark, Germany, Israel, the Netherlands, Spain, Switzerland, the UK, and the USA. The reported prevalence of monthly breast self‐examination was 0–48%; for yearly clinical breast examination 27–54%; and for biennial mammography 0–71%. The substantial methodologic heterogeneity prevented a meta‐analysis. Nonetheless, irrespective of host country, healthcare access, or educational level, the findings consistently indicated that Eastern European immigrant women underutilize breast cancer screening largely because of insufficient knowledge about early detection and an external locus of control regarding decision making in health matters.ConclusionsThis is a vulnerable population for whom the implementation of culturally tailored breast cancer screening programs is needed. As with other underscreened immigrant/minority groups, Eastern European women's inadequate engagement in prevention is troublesome as it points to susceptibility not only to cancer but also to other serious conditions for which personal action and responsibility are critical. Copyright © 2013 John Wiley & Sons, Ltd.
Metabolomic signatures of aggressive prostate cancer
Authors: McDunn Jonathan E. , Li Zhen , Adam Klaus‐Peter , Neri Bruce P. , Wolfert Robert L. , Milburn Michael V. , Lotan Yair , Wheeler Thomas M. 
Published: July 2013

AbstractBACKGROUNDCurrent diagnostic techniques have increased the detection of prostate cancer; however, these tools inadequately stratify patients to minimize mortality. Recent studies have identified a biochemical signature of prostate cancer metastasis, including increased sarcosine abundance. This study examined the association of tissue metabolites with other clinically significant findings.METHODSA state of the art metabolomics platform analyzed prostatectomy tissues (331 prostate tumor, 178 cancer‐free prostate tissues) from two independent sites. Biochemicals were analyzed by gas chromatography–mass spectrometry and ultrahigh performance liquid chromatography–tandem mass spectrometry. Statistical analyses identified metabolites associated with cancer aggressiveness: Gleason score, extracapsular extension, and seminal vesicle and lymph node involvement.RESULTSProstate tumors had significantly altered metabolite profiles compared to cancer‐free prostate tissues, including biochemicals associated with cell growth, energetics, stress, and loss of prostate‐specific biochemistry. Many metabolites were further associated with clinical findings of aggressive disease. Aggressiveness‐associated metabolites stratified prostate tumor tissues with high abundances of compounds associated with normal prostate function (e.g., citrate and polyamines) from more clinically advanced prostate tumors. These aggressive prostate tumors were further subdivided by abundance profiles of metabolites including NAD+ and kynurenine. When added to multiparametric nomograms, metabolites improved prediction of organ confinement (AUROC from 0.53 to 0.62) and 5‐year recurrence (AUROC from 0.53 to 0.64).CONCLUSIONSThese findings support and extend earlier metabolomic studies in prostate cancer and studies where metabolic enzymes have been associated with carcinogenesis and/or outcome. Furthermore, these data suggest that panels of analytes may be valuable to translate metabolomic findings to clinically useful diagnostic tests.Prostate 73: 1547–1560, 2013© 2013 Wiley Periodicals, Inc.
Mass spectrometric studies shed light on unusual oxidative transformations of 1,2‐dehydro‐N‐acetyldopa
Authors: Abebe Adal , Kuang Qun F. , Evans Jason J. , Sugumaran Manickam 
Published: July 2013

RATIONALELamellarins are a group of over 70 plus bioactive marine natural compounds possessing a 6,7‐dihydroxycoumarin moiety. Although they appear to derive from 3,4‐dihydroxyphenylalanine (dopa), practically nothing is known about the metabolic fate of these compounds. Biochemical considerations indicate that they could arise from a N‐acetyl‐1,2‐dehydrodopa precursor through oxidative cyclization reaction.METHODSTo assess the above hypothesis, we synthesized N‐acetyl‐1,2‐dehydrodopa and conducted oxidation studies with commercially available mushroom tyrosinase and evaluated the course of the reaction with reversed‐phase liquid chromatography/mass spectrometry (LC/MS).RESULTSMushroom tyrosinase readily oxidized N‐acetyl‐1,2‐dehydrodopa – not to the normally expected quinone – but to an unstable quinone methide isomer, which rapidly cyclized to produce the dihydroxycoumarin product, 3‐aminoacetyl esculetin. Interestingly, 3‐aminoacetyl esculetin was further oxidized to a second quinone methide derivative that exhibited an addition reaction with the parent dihydroxycoumarin generating dimeric and other oligomeric products in the reaction mixture.CONCLUSIONSLC/MS analysis of the N‐acetyl‐1,2‐dehydrodopa oxidation reaction reveals not only a possible novel oxidative cyclization route for the biosynthesis of coumarin‐type dehydrodopa compounds in marine organisms, but also unusual oxidative transformations of dehydro dopa derivatives. Copyright © 2013 John Wiley & Sons, Ltd.
3D parameter to quantify the anisotropy measurement of periodic structures on rough surfaces
Authors: Guillemot G. , Bigerelle M. , Khawaja Z. 
Published: July 2013

SummaryIn this paper, a new 3D roughness parameter, Sreg, is proposed to quantify the regularity of a surface, independent of the amplitude and the SCANNING 36:127–133, 2014. © 2013 Wiley Periodicals, Inc.
Search for ν μ → ν e oscillations with the OPERA experiment in the CNGS beam
Authors:   The OPERA collaboration, Agafonova N. , Aleksandrov A. , Anokhina A. , Aoki S. , Ariga A. , Ariga T. , Autiero D. , Badertscher A. , Dhahbi A. Ben , Bertolin A. , Bozza C. , Brugnera R. , Brunet F. , Brunetti G. , Buettner B. , Buontempo S. , Chaussard L. , Chernyavsky M. , Chiarella V. , Chukanov A. , Consiglio L. , D’Ambrosio N. , De Lellis G. , De Serio M. , del Amo Sanchez P. , Di Crescenzo A. , Di Ferdinando D. , Di Marco N. , Dmitrievsky S. , Dracos M. , Duchesneau D. , Dusini S. , Dzhatdoev T. , Ebert J. , Ereditato A. , Ferber T. , Fini R. A. , Fukuda T. , Garfagnini A. , Giacomelli G. , Goellnitz C. , Goldberg J. , Gornushkin Y. , Grella G. , Grianti F. , Guler A. M. , Gustavino C. , Hagner C. , Hamada K. , Hara T. , Hierholzer M. , Hollnagel A. , Hosseini B. , Ishida H. , Ishiguro K. , Jakovcic K. , Jollet C. , Juget F. , Kamiscioglu C. , Kamiscioglu M. , Kawada J. , Kim J. H. , Kim S. H. , Kimura M. , Kitagawa N. , Klicek B. , Kodama K. , Komatsu M. , Kose U. , Kreslo I. , Lauria A. , Lenkeit J. , Ljubicic A. , Longhin A. , Loverre P. , Malgin A. , Mancini-Terracciano C. , Mandrioli G. , Marteau J. , Matsuo T. , Matveev V. , Mauri N. , Medinaceli E. , Meisel F. W. , Meregaglia A. , Migliozzi P. , Mikado S. , Minotti A. , Monacelli P. , Montesi M. C. , Morishima K. , Muciaccia M. T. , Nakamura M. , Nakano T. , Nakatsuka Y. , Naumov D. , Niwa K. , Ogawa S. , Okateva N. , Olchevsky A. , Omura T. , Ozaki K. , Paoloni A. , Park B. D. , Park I. G. , Pastore A. , Patrizii L. , Pennacchio E. , Pessard H. , Pistillo C. , Podgrudkov D. , Polukhina N. , Pozzato M. , Pretzl K. , Pupilli F. , Rescigno R. , Roda M. , Roganova T. , Rokujo H. , Rosa G. , Rostovtseva I. , Rubbia A. , Russo A. , Ryazhskaya O. , Sato O. , Sato Y. , Schchedrina T. , Schembri A. , Schmidt-Parzefall W. , Shakiryanova I. , Sheshukov A. , Shibuya H. , Shiraishi T. , Shoziyoev G. , Simone S. , Sioli M. , Sirignano C. , Sirri G. , Spinetti M. , Stanco L. , Starkov N. , Stellacci S. M. , Stipcevic M. , Strauss T. , Strolin P. , Suzuki K. , Takahashi S. , Tenti M. , Terranova F. , Tioukov V. , Tolun P. , Tufanli S. , Vilain P. , Vladimirov M. , Votano L. , Vuilleumier J.-L. , Wilquet G. , Wonsak B. , Yoon C. S. , Yoshida J. , Zaitsev Y. , Zemskova S. , Zghiche A. 
Published: July 2013

AbstractA first result of the search forνμ→νeoscillations in the OPERA experiment, located at the Gran Sasso Underground Laboratory, is presented. The experiment looked for the appearance ofνein the CNGS neutrino beam using the data collected in 2008 and 2009. Data are compatible with the non-oscillation hypothesis in the three-flavour mixing model. A further analysis of the same data constrains the non-standard oscillation parametersθnewand$ \varDelta m_{\mathrm{new}}^2 $suggested by the LSND and MiniBooNE experiments. For large$ \varDelta m_{\mathrm{new}}^2 $values (>0.1 eV2), the OPERA 90% C.L. upper limit on sin2(2θnew) based on a Bayesian statistical method reaches the value 7.2 × 10−3.
Mother–calf interactions and social behavior development in Commerson’s dolphins (Cephalorhynchus commersonii)
Authors: Sakai Mai , Morisaka Tadamichi , Iwasaki Mari , Yoshida Yayoi , Wakabayashi Ikuo , Seko Atsushi , Kasamatsu Masahiko , Kohshima Shiro 
Published: July 2013

Abstract
Mother–calf interactions and the behaviors of mothers during separation from their calves were examined in four Commerson’s dolphin (Cephalorhynchus commersonii) mother–calf pairs. Four infants were observed: 56.8 h over 30 days from birth to 263 days of age, 36.9 h over 20 days from birth to 149 days of age, 10.4 h over 3 days from birth to 2 days of age, and 15.0 h over 3 days from birth to 2 days of age. All four pairs shared common characteristics in the rate and frequencies of mother–calf interactions and the behaviors of mothers during the first week of life. After the first week, individual differences in changes in the frequency of each behavior were observed. The three behaviors considered representative of maternal care (parallel swimming, synchronous breathing, and body-to-body contact) were frequently performed in the first week; thereafter, the frequencies declined. Separate behaviors of mothers were infrequent during the first week and increased with an increase in infants’ age. Bumping by infants increased with time, suggesting an increase in soliciting by calves and conflict between mothers and calves. The frequency of flipper-to-body rubbing also changed but in a complex manner, probably because the calves needed to learn how to perform this behavior from their mothers and because initiator and recipient of this behavior can be changed quickly.