bluuebunny/crossref_metadata_2025_split huggingface dataset:
Influenza A defective viral genomes and non-infectious particles are increased by host PI3K inhibition via anti-cancer drug alpelisib
Authors: Agu Ilechukwu , José Ivy , Ram Abhineet , Oberbauer Daniel , Albeck John , Díaz Muñoz Samuel L. 
Published: July 2024

AbstractRNA viruses produce abundant defective viral genomes during replication, setting the stage for interactions between viral genomes that alter the course of pathogenesis. Harnessing these interactions to develop antivirals has become a recent goal of intense research focus. Despite decades of research, the mechanisms that regulate the production and interactions of Influenza A defective viral genomes are still unclear. The role of the host is essentially unexplored; specifically, it remains unknown whether host metabolism can influence the formation of defective viral genomes and the particles that house them. To address this question, we manipulated host cell anabolic signaling activity and monitored the production of defective viral genomes and particles by A/H1N1 and A/H3N2 strains, using a combination of single-cell immunofluorescence quantification, third-generation long-read sequencing, and the cluster-forming assay, a method we developed to titer defective and fully-infectious particles simultaneously. Here we show that alpelisib (Piqray), a highly selective inhibitor of mammalian Class 1a phosphoinositide-3 kinase (PI3K) receptors, significantly changed the proportion of defective particles and viral genomes (specifically deletion-containing viral genomes) in a strain-specific manner, under conditions that minimize multiple cycles of replication. Alpelisib pre-treatment of cells led to an increase in defective particles in the A/H3N2 strain, while the A/H1N1 strain showed a decrease in total viral particles. In the same infections, we found that defective viral genomes of polymerase and antigenic segments increased in the A/H1N1 strain, while the total particles decreased suggesting defective interference. We also found that the average deletion size in polymerase complex viral genomes increased in both the A/H3N2 and A/H1N1 strains. The A/H1N1 strain, additionally showed a dose-dependent increase in total number of defective viral genomes. In sum, we provide evidence that host cell metabolism can increase the production of defective viral genomes and particles at an early stage of infection, shifting the makeup of the infection and potential interactions among virions. Given that Influenza A defective viral genomes can inhibit pathogenesis, our study presents a new line of investigation into metabolic states associated with less severe flu infection and the potential induction of these states with metabolic drugs.
Gender wage gap by university major: an empirical assessment using Spanish data
Authors: Callado Muñoz Francisco Jose , Utrero-González Natalia 
Published: July 2024

Purpose
This paper aims to analyse gender wage gaps by university majors along the entire wage distribution in Spain before and after the 2008 financial crisis.

Design/methodology/approach
The authors perform unconditional quantile regressions to estimate the gender wage gap and use the Oaxaca–Blinder approach to decompose the gender gap.

Findings
The observed gender gap among graduates hides significant differences across various fields of study, and both the gap and its unexplained part are highly dependent on the position in the distribution. Engineering and Experimental sciences are the fields with the highest wage differences, and the gap size worsens with the crisis. Health and Humanities, the majors with the highest women presence, show a higher proportion of unexplained part at the bottom tail of the wage distribution, especially after the crisis, suggesting that discrimination against low-paid women has aggravated in these majors.

Originality/value
The paper adds to the existing knowledge by analysing the role that educational decisions play in shaping the wage gap, the variability of the gap along the wage distribution and its response to a change in macroeconomic conditions.
Mitigating cyberloafing through employee adaptability: the roles of temporal leadership, teamwork attitudes and competitive work environment
Authors: Hessari Hassan , Daneshmandi Fatemeh , Busch Peter , Smith Stephen 
Published: July 2024

PurposeIn the evolving digital work landscape, where cyberloafing has become a notable challenge, this study aims to investigate the mechanisms through which organizations can effectively reduce such behaviors. Specifically, the research explores the role of employee adaptability in mitigating cyberloafing, taking into account the influences of temporal leadership, teamwork attitudes, and competitive work environments.Design/methodology/approachUtilizing the broaden-and-build theory and the job demands-resources (JD-R) model, we analyzed data from 245 employees through structural equation modeling (SEM) to investigate how various factors influence cyberloafing.FindingsThe results indicate that employee adaptability significantly mitigates cyberloafing and serves as a mediating factor between temporal leadership, teamwork attitudes, and the impact of competitive work environments on cyberloafing. Temporal leadership and teamwork attitudes positively correlate with increased adaptability, thereby reducing cyberloafing. Conversely, competitive work environments, while slightly enhancing adaptability, substantially increase cyberloafing.Originality/valueThe study contributes new insights into the dynamics of cyberloafing, emphasizing the critical roles of adaptability, teamwork attitudes, and temporal leadership in reducing such behaviors. It underscores the need for organizations to foster a supportive culture that minimizes competitive pressures and promotes teamwork and leadership strategies conducive to high productivity and minimal cyberloafing. This research offers practical implications for designing workplace strategies aimed at boosting productivity and curbing undesirable online behaviors during work hours.
Manufacturing SME risk management in the era of digitalisation and artificial intelligence: a systematic literature review
Authors: Sotamaa Tero , Reiman Arto , Kauppila Osmo 
Published: July 2024

PurposeThe purpose of this paper is to explore companies’ business risks and challenges across macro- and micro-environments, as well as how small and medium-sized enterprises (SMEs) can benefit from digital technologies, including artificial intelligence (AI), as part their risk-management (RM) strategies in the face of recent disruptive events.Design/methodology/approachWe perform a literature review on risk management and business continuity (BC) in the context of SMEs, both in general and specifically in the manufacturing sector.FindingsThe critical importance of RM and BC for SMEs is highlighted. The review underscores the significant impact of recent disruptions on SMEs and reveals a range of risk factors affecting their BC. Moreover, the review recognises how SMEs, in general, and manufacturing SMEs, in particular, can benefit from using digital technologies and AI as essential components of their RM.Originality/valueThe review highlights transformative role of digital technologies and AI in enhancing RM. Through a systematic classification of risk factors within macro- and micro-environments, this novel approach provides a structured foundation for future research. It provides practical value by enabling SMEs to integrate dynamic capabilities and adaptive capacities through the adaption of digital technologies and AI into their RM.
What makes a workday meaningful? Evidence on the role of task significance, competence and subjective meaningful work
Authors: Tommasi Francesco , Sartori Riccardo , Ceschi Andrea , Dickert Stephan 
Published: July 2024

PurposeThe construct of meaningful work is a relevant topic for the managerial literature interested in job design, employees’ motivation, and job performance. The current research seeks to improve our knowledge on meaningful work by exploring the processes by which a workday is experienced as meaningful.Design/methodology/approachAdopting the lens of the Job Demands-Resources model and Self-Determination theory, we argue that work conditions and psychological conditions are associated with the experience of meaningful work on a daily basis. Moreover, we propose that the experience of meaningful work on a long-term basis (i.e. the evaluation of one’s own work as holding significance per se) intensifies the associations between daily conditions and the experience of meaningful work. We collected data via an event-based longitudinal diary study for a total sample of N = 114 employees from six organizations and N = 545 observations.FindingsResults of the multilevel analysis showed that competence and task significance led to the experience of meaningful work during working days. Moreover, cross-level analyses revealed that these associations are stronger for employees who experience their work to be meaningful in the long-term.Originality/valueThe novelty of the present study lies in highlighting the role of specific factors contributing to the experience of meaningful work during a workday. These findings help specify targets and organizational and individual dimensions to be addressed by managerial interventions to ensure employees' meaningful work experience.
Critical success factors in Malaysian housing projects: examining contractual, process and human management with knowledge sharing moderation
Authors: A. Wahab Adilah , Bohari Siti Aisah , Sheng Wei Chyi 
Published: July 2024

Purpose
The purpose of this paper is to examine the importance of contractual management (CM), process management (PM) and human management (HM) factors as critical success factors (CSFs) in Malaysian housing projects. Additionally, it delves into the moderating influence of knowledge sharing (KS) on the relationship between HM and project success.

Design/methodology/approach
This study used a survey-based instrument to collect data from a total of 133 G7 class contractors. The stratified sampling method was used for data collection. Subsequently, structural equation modeling with SmartPLS was used for model evaluation.

Findings
The findings of this study indicate that CM, PM and HM exhibit significant relationships with housing project success. Furthermore, the research reveals that KS acts as a moderator in the relationship between HM practices and the success of housing projects.

Research limitations/implications
Although this study identified a significant relationship in explaining CSFs for housing project success in Malaysia, it only considers internal CSFs such as CM, PM and HM. It is suggested that future research incorporate external factors such as political support, national policy, currency stability and industry structure to provide a more comprehensive understanding of housing project success.

Originality/value
The results provide supportive evidence that CM, PM and HM are important CSFs in the success of housing projects. This finding is consistent with relational contractual theory, systems theory and social interaction theory. Moreover, the research underscores the nuanced impact of KS, serving as a moderating factor in the association between HM and project success. Consequently, these outcomes substantiate the applicability of the socialization, externalization, combination and internalization framework within the construction sector, particularly within the sphere of housing sector.
ESG performance and corporate volatility: an empirical exploration in an emerging economy
Authors: Sharma Sudhi , Aggarwal Vaibhav , Reepu  , Mehta Gitanjali Kaur 
Published: July 2024

PurposeThis study aims to investigate into the dynamic connection between ESG scores and the volatility term structure for Indian companies listed BSE. The study divides the BSE-100 listed companies into two panels based on their median ESG scores in 2022, creating high and low ESG scoring groups to capture volatility structure.Design/methodology/approachThe study employs time-varying symmetric and asymmetric GARCH models and followed by continuous Wavelet to capture volatility structure and explore comparative resilience behavior.FindingsThe study found similar volatility patterns regardless of ESG scores, nudging doubt on the direct impact of ESG on volatility. Additionally, both high- and low-ESG-scored companies displayed high vulnerabilities during the pandemic, raising questions about the effectiveness of ESG frameworks in capturing risks. Finally, by examining the resilience behavior of ESG-scored companies during the pandemic, our study contributes to the evolving understanding of the intersection between ESG performance and crisis response.Practical implicationsThe study carries vital implications for investors and policymakers. It highlights the urgent need to strengthen the ESG framework and scores to shield investors from short- and long-term volatilities and economic vulnerabilities.Originality/valueTo the best of the authors’ knowledge, this is the first study investigating the Indian market by examining the volatility structure and resilience behavior of high- and low-ESG-scored companies during the pandemic.Peer reviewThe peer review history for this article is available at: https://publons.com/publon/10.1108/IJSE-02-2024-0113
The role of safety climate in occupational health and safety information seeking: extending risk perception attitude framework
Authors: Fung Timothy K.F. 
Published: July 2024

PurposeThis study is a theory-building effort to extend the risk perception attitude (RPA) framework by considering an organization-related factor. Specifically, this study examined how an organization-related factor, namely safety climate, and individual-related factors, namely risk perception and efficacy belief, jointly influence flight attendants’ occupational health and safety (OHS) information seeking intent.Design/methodology/approachAbout 486 flight attendants from an international air carrier, based in Hong Kong, participated in an online survey. Hierarchical regression was employed to examine the three-way interaction of risk perception, efficacy belief, and safety climate.FindingsResults showed that safety climate moderated the effect of efficacy belief on the relationship between risk perception and OHS information seeking intent. For flight attendants who perceived a high safety climate, those who felt more efficacious had a higher intent for OHS information seeking than those who felt less efficacious. In contrast, for flight attendants who perceived a low safety climate, when they perceived a high level of risk, those with low efficacy had a higher information seeking intent than those with high efficacy.Originality/valueAlthough the RPA framework has shown its potential to explicate how individual employees engage in OHS information seeking behavior, the framework has largely overlooked the importance of organization-related factors as an influential shaping force of individual employees’ behavior. To fill this research gap, this study extends the RPA framework by examining how safety climate moderates the relationship between risk perception and efficacy belief on flight attendants’ OHS information seeking intent. Safety climate also plays an important role in segmenting audience groups for OHS promotion.
Investigation on the dynamic characteristics for high-speed mechanical seal considering turbulent cavitating flow and inertia effect
Authors: Wang Yunlei , Hao Zhishuang , Wu Jiuhui 
Published: July 2024

Purpose
This study aims to investigate the dynamic characteristics of a high-speed mechanical seal by considering the flow regime, cavitation phenomenon and inertia effect.

Design/methodology/approach
Based on the high-speed conditions of a mechanical seal with a low-viscosity fluid, a multi-factor coupled lubrication model of a mechanical seal is established. The perturbation Reynolds equation set is derived using the perturbation method, and the effects of turbulent flow and inertia on sealing performance are discussed.

Findings
The results indicate that turbulence significantly influences the dynamic characteristics of low-viscosity fluids under high-speed conditions.

Originality/value
The results of the dynamic characteristics presented in this study are expected to provide guidance for the design of mechanical seals.
Globalization, fractionalized governments and expansionary fiscal policy
Authors: Hwang Wonjae , Lee Hoon , Lee Sang-Hwan 
Published: July 2024

PurposeAs a response to challenges that globalization poses, governments often utilize an expansionary fiscal policy, a mix of increased compensation spending and capital tax cuts. To account for these policy measures that are consistent with neither the compensation nor the efficiency hypothesis, this study examines government fractionalization as the key conditional factor.Design/methodology/approachWe test our hypothesis with a country-year data covering 24 OECD countries from 1980 to 2011. To examine how a single country juggles compensation spending and capital taxation policies jointly, we employ a research strategy that classifies governments into four categories based on their implementation of the two policies and examine the link between imports and fiscal policy choices conditioned on government fractionalization.FindingsThis study shows that highly fractionalized governments are more likely to implement an expansionary fiscal policy than marginally fractionalized governments as a policy response to economic globalization and import shock.Social implicationsOur findings imply that fractionalized governments are likely to face budget deficits and debt crises, as the expansionary fiscal policy persists over time.Originality/valueBy examining government fractionalization as one of the critical factors that constrain the fiscal policy choice, this study enhances our understanding of the relationship between economic globalization and compensation or efficiency policies. The arguments and findings in this study explain why governments utilize the seeming incompatible policy preferences over increased compensation spending and reduced capital tax burdens as a response to globalization, potentially subsuming both hypotheses.
Exploration-oriented high-tech manufacturers’ export marketing internalization in emerging markets: the moderating role of relational ties with supply chain peers
Authors: Cheng Hsianglin , Wang Chunhsien 
Published: July 2024

Purpose
This study aims to argue that manufacturers with more exploration orientation (compared to exploitation orientation) have higher degrees of export marketing internalization (EMI) of branding and channels.

Design/methodology/approach
The authors use a multisource survey collecting data from 161 Taiwanese high-tech manufacturers in emerging markets.

Findings
The results show that manufacturers with more exploration orientation have higher degrees of EMI of both branding and channels. This work also reveals that relational ties with supply chain peers can strengthen this proposed positive effect on the EMI of channels while weakening the positive proposed effect on the EMI of branding.

Originality/value
Accordingly, this study enriches the resource-based view (RBV) literature by showing how firms’ unique resource portfolios affect their adopted EMI strategies in two ways: (1) firms design their EMI based on their value maximization of core competences (e.g. ambidexterity capability), and (2) firms face resource inconsistency when designing their EMI of different marketing activities.
Project management education in the Kingdom of Saudi Arabia: a multi-method approach
Authors: Ali Jamshid , Qabil Alsolamy Majed , Alotaibi Mohammed Saeed , Dahinine Benameur 
Published: July 2024

Purpose
The purpose of the study was to assess the current state and demand of the project management education. Project management has gained increasing importance as a critical discipline for achieving successful project outcomes in various industries and sectors. In the Kingdom of Saudi Arabia (KSA), the demand for skilled project management professionals has increased due to different developmental projects and ambitious initiatives like NEOM.

Design/methodology/approach
The study adopted a qualitative multi-method approach to comprehend the objective in depth. In the first round, a systematic literature review (SRL) was applied to explore the state of project management education (PME) in KSA. In the second, structured interviews with professionals were arranged to explore the phenomenon of interest in more detail. Moreover, three case studies were also included to support, comprehend and generalize the findings.

Findings
The study highlights the strengths and gaps in PME. The study also provides an insight to enhance the quality and effectiveness of the PME in KSA. Besides these, the research recommends exploring different avenues for the promotion of PME in the country.

Originality/value
The study offers a pioneering exploration of PME in KSA. It uses a multi-method approach to unveil unique insights into the country's educational landscape and its alignment with global industry standards.
Investigations into 4D printed PLA/graphite composite with thermal induced shape memory effect
Authors: Arora Kunal , Kumar Mohit , Sharma Varun 
Published: July 2024

Purpose
The paper aims to fabricate shape memory composites using polylactic acid (PLA) matrix and graphite. Shape memory polymers are a promising family of materials for biomedical applications because of their favourable mechanical properties, fast reactions and good biocompatibility. For most SMPs, however, achieving controllable sequential shape change is challenging.

Design/methodology/approach
In the present work, 4D printing technology is used to fabricate shape memory composites using polylactic acid (PLA) matrix and graphite. A comparative study of pure PLA and graphite’s different weight % composition has been done.

Findings
By carefully managing the deformation state, PLA with graphite shape memory composites produced controllable sequential deformation with an amazing shape memory effect. Surface morphology, thermal properties, melt flow index and shape recovery tests have all been carried out to assess the qualities of manufactured samples.

Originality/value
This is a one-of-a-kind to fabricate shape memory composites using graphite and a PLA matrix. Thus, this research attempts to deliver the possible use of PLA/graphite composites fabricated using 4D printing in robotics and biomedical devices.

Graphical Abstract