bluuebunny/crossref_metadata_2025_split huggingface dataset:
Тенденции изменения климата и их проявления на водосборе бассейна реки Асса-Талас
Authors: Мустафаев Ж.С. , Козыкеева А.Т. , Абдешев К.Б. , Турсынбаев Н.А. 
Published: June 2024

Для прогноза современных изменений климата и их проявления на водосборе бассейна реки Асса-Талас создана база исследований, собранная из многолетних информационно-аналитических материалов РГП «Казгидромет» и «Кыргызгидромет», Всемирной метеорологической организации и справочно-информационного портала «Погода и климат», позволяющих изучить тенденции в пространственно-временном масштабе. На основе созданной базы исследования по метеорологическим станциям Сусамыр, Талас, Кызыл-Адыр, Нурлыкент, Тараз, Саудакент и Ойык, расположенных на водосборных территориях бассейна реки Асса-Талас, с использованием программы Microsoft Excel построены графики временного ряда среднегодовых температур воздуха и годовых атмосферных осадков и получены уравнения их линейного тренда, которые позволили разработать математическую модель темпа прироста климатических и гидрологических показателей, имеющих достаточно высокий физический и математический смысл, базирующегося на законе природы. Анализ темпа роста климатических показателей на территории водосбора бассейна реки Асса-Талас показывает, что их количественные значения по всем метеорологическим станциям не совпадают, то есть в современных условиях темп прироста среднегодовых температур воздуха в сравнении темпа роста годовых атмосферных осадков в два раза больше, который способствует повышению дефицита водопотребления естественных и культурных сельскохозяйственных угодий до 25 % и уменьшению поверхностного гидрологического стока до 15 %, сравнительно к середине ХХ века, обеспечивающих водную безопасность региона.
Culture of sheep poxvirus in a 3D Vero cells culture model
Authors: Nakhanov A.K. , Zhapparova G.A. , Bulatov Ye.A. , Terebay A.A. , Seidakhmetova B.A. , Sametova Zh.Zh. , Turyskeldi Sh.S. 
Published: June 2024

In the article the production of a three-dimensional culture of Vero cells using the methods of “hanging drop” and roller cultivation was described. The resulting spheroids remain viable for more than four days. For the formation of large spheroids with good proliferative activity, the inoculum concentration should be 200000 cells/ml. The additional study of the cell proliferation index in spheroids showed that cell growth was 3.5 times on the second day. A comparative study of the biological activity of the sheep poxvirus in 3D cell culture was carried out in comparison with traditional2D cultivation. After infection of the spheroids with sheep poxvirus in the first passage, the virus titer was 5.33±0.04 lg TCID50/ml. At the second and third passages, the biological activity of the virus increased to 6.33±0.04 and 6.41±0.04 lg TCID50/ml, respectively. Considering these data, three-dimensional culture allows for obtaining much cell biomass with high biological activity compared to the traditional culture method.
Frequency of rs731236, rs7975232 and rs1544410 single nucleotide polymorphisms of Vitamin-D Receptor (VDR) gene among the Kazakh ethnic group
Authors: Protas V.V. , Pogossyan G.P. , Li K.G. 
Published: June 2024

In the article the pilot study results of the genotypes and individual allele’s frequency of single nucleotide polymorphisms (SNPs) rs731236, rs7975232 and rs1544410 in vitamin D receptor (VDR) gene were presented. The participants were representatives of the Kazakh ethnic group. The SNPs were determined by real-time polymerase chain reaction using the amplification-refractory mutation system (ARMS) technology. The relevance of the study is that rs731236, rs7975232 and rs1544410 contribute to the regulation of VDR gene expression. This affects the synthesis of the VDR protein and its activity as a transcription factor. VDR regulates various metabolic pathways, including the immune response to infectious diseases. In rs731236, the A allele (68.9 %) prevailed over the G (31.1 %). The AA, AG and GG genotypes were 52.1 %, 33.6 % and 14.3 %, respectively. For rs7975232, there were no significant differences in the alleles A and C (42.4 % vs. 57.6 %). There was a predominance of AC and CC genotypes (39.5 % and 37.8 %, respectively), over AA (22.7 %). Allele A of rs1544410 was not found in the Kazakh population. The allele C was 65.6 %, T — 25.6 %, and G — 8.8 %. The frequencies of the CC and CT genotypes were similar (40.3 % vs. 39.5 %). It is possible to study the influence of these SNPs on COVID-19 susceptibility among Kazakhs.
Selection of Bergenia crassifolia specimens based on a complex of decorative characteristics in the flora of Kazakhstan Altai and their introduction in the Altai Botanical Garden
Authors: Tuchina L.A. , Danilova A.N. , Sumbembayev A.A. , Lagus O.A. 
Published: June 2024

The purpose of the study is to select Bergenia crassifolia specimens from different eco-geographical habitats in natural populations of the Kazakhstan Altai based on a complex of decorative characteristics and their introduction testing in the Altai Botanical Garden, creating promising forms for inclusion in the landscaping assortment. The growth of B. crassifolia in the Kazakhstan Altai has been established on the mountain ranges of the Southern and Southwestern Altai in the mountain forest and alpine belts with a vertical distribution threshold of 1100–1800 m above sea level. For introduction, promising samples of B. crassifolia based on economically valuable indicators were selected on the ridges of the Southern and Southwestern Altai. Classical botanical methods were used. Based on the results of the research, a collection of 74 specimens of B. crassifoliа was created in the Altai Botanical Garden, among them 59 decorative specimens with high winter hardiness, a full cycle of seasonal development, responding to weather conditions by changing the duration of the phenological phases of development. Based on the timing of flowering, the samples are classified as spring-early flowering and spring-mid flowering. Based on the results of a comparative assessment, 8 forms were recommended for inclusion in the landscaping assortment with a decorative score of 87–98 points.
Species Suaeda Forssk. of the Aral-Balkhash region flora in the collections of the Herbarium (AA)
Authors: Ussen S , Vesselova P.V. , Kudabayeva G.M. , Kurmanbayeva M.S. , Osmonali B.B. 
Published: June 2024

In the article a complete list of specimens of species of the genus Suaeda Forssk. ex J.F. Gmel. of the Aral-Balkhash region, stored in the herbarium fund of the Institute of Botany and Phytointroduction (Almaty, Kazakhstan) was provided. Suaeda species are divided into 5 sections (Schanginia C.A. Mey, Lachnostigma Iljin, Conosperma Iljin, Physophora Iljin, Heterosperma Iljin). The aim of the research was to critically study the specimens of species of the genus Suaeda of the Aral-Balkhash region, available in the Herbarium (AA) for further revision of the genus. This territory includes 5 floristic regions (14 — Aral Sea, 15 — Kyzylorda, 16 — Betpakdala, 17 — Muyunkum (Moiynkum) and 18 — Balkhash-Alakul.). During the screening of species of the genus within the study region, 240 herbarium specimens were reviewed, belonging to 15 species. A comparison of the representation of species in the collection fund of the Herbarium with the data of literary sources was carried out. Floristic areas have been identified in which, despite the availability of information about the presence of the studied species on their territory, there is no herbarium material. At the same time, floristic areas are noted in which the presence of certain species of Suaeda was not previously cited in literary sources, but they are present in the collections of the Herbarium. The degree of study of each region was determined for the further compilation of the current expedition route in order to replenish the herbarium fund. The paper presents a synopsis of the studied group of species with an information block of herbarium labels for each taxon. The features of the distribution of Suaeda species of the Aral-Balkhash region in 5 floristic regions with an indication of the number of specimens for each taxon are revealed.
Cпутник-V вакцинасымен вакцинацияланған адамдардың TLR7, TLR4, TMPRSS13, IL-4 және IFN-γ гендерінің экспрессия динамикасын бағалау
Authors: Кадырова И.А. , Балгабекова А.Б. , Барханская В.И. , Әбсағит Л.Н. 
Published: June 2024

Мақалада Спутник-V вакцинасымен иммундалғаннан кейін туындаған TLR7, TLR4, TMPRSS13, IFN-γ, IL-4 гендерінің экспрессиясының өзгерістері зерттелген. Жұмыс Қарағанды медицина университетінің базасында жүргізілді. COVID-19-ға қарсы екпе алмаған еріктілерден веноздық қан үлгілері вакцинациядан бұрын, Спутник-V 1- және 2-дозаларын енгізгеннен 21 күн өткеннен кейін және 6 айдан соң жиналды. Биологиялық үлгілерді жинағаннан кейін, вакцинаны дельта тәрізді бұлшық етке 1±0,5×1011 рекомбинантты аденовирустық (rAd) бөлшектері бар Спутник-V 0,5 мл дозасы енгізілді. 1 және 2 дозалары, сәйкесінше, 21 күн аралығымен енгізілетін rАd26 және rAd5-тен тұрды. Зерттеу басталғанға дейін екі апта ішінде респираторлық симптомдардың болуы немесе зертханалық расталған COVID-19 диагнозын есептемеу критерийі болды. Үлгілерден РНҚ бөліп алған соң, кері транскрипциямен полимераздық тізбекті реакция өткізілді. Статистикалық өңдеу IBMSPSS 26 нұсқасында орындалды. Краскел-Уоллис критерийі, Пирсон χ2 немесе топаралық салыстырулар үшін нақты Фишер критерийі қолданылды. 95 % сенімділік интервалдары (СИ) биномдық «дәл» әдіспен есептелді. Алынған нәтижелер бойынша TLR7, TLR4, TMPRSS13, IFN-γ және IL-4 гендерінің гиперэкспрессиясы анықталды. Бұл Спутник-V вакцинациясынан кейін иннативті иммунитеттің ұзақ уақыт белсендірілуін көрсетеді. Зерттеу нәтижелері аденовирустық векторларға негізделген вакциналарды қолдана отырып, адамдарда жаттыққан иммунитетті индукциялау мүмкіндігі туралы гипотезаны растайды. Біздің нәтижелеріміз қоғамды жұқпалы аурулардан қорғауды жақсарту перспективаларын ашатын жақсырақ вакцинация стратегиялары мен жаңа вакциналарды әзірлеуге негіз бола алады.
Некоторые данные из Архива А.И. Шренка об использовании растений в народной медицине населением Казахстана в первой половине XIX столетия
Authors: Беделбаева М.В. , Лебедева Т.П. 
Published: June 2024

В ходе работы с материалами Гербария Ботанического института им. В.Л. Комарова РАН (г. Санкт-Петербург, РФ) и Архивом А.И. Шренка, который хранится в Санкт-Петербургском отделении Архива РАН, был найден датированный 1841 годом неопубликованный ранее документ под названием «Выписка из медико-топографического описания Кокчетавского округа лекаря Богословского». В нем содержатся любопытные сведения об использовании населением некоторых местных и привозных растений для лечения ряда болезней (цинга, воспаление глаз, горячка, цистит, чесотка, лишай и др.). Вероятно, как раз эти сведения и заинтересовали А.И. Шренка, собиравшего во время своих путешествий самую разнообразную информацию о мало исследованных в этот период землях. В статье описано применение в лекарственных целях Allium cepa L., Lithospermum officinale L., Atraphaxis frutescens (L.) K. Koch, Pentanema salicinum (L.) D. Gut. Larr., Santos-Vicente, Anderb., E. Rico & M.M. Mart. Ort., Inula helenium L. и др., уточнена видовая принадлежность некоторых из них. Такие данные дополняют существующие в науке представления о лекарственных свойствах растений и использовании их для лечения в первой половине XIX века.
Heavy Naphtha Desulfurization by Ozone Generated via the DBD Plasma Reactor
Authors: Abdullah Noor M. , Hussien Hussien Q. , Jalil Rana R. 
Published: June 2024

This work presents an investigation into the ultra-desulfurization of heavy naphtha fuel (model using BT and DBT) using oxidation and solvent extraction techniques. Ozone produced by the DBD (Dielectric barrier discharge) plasma generator was employed in the oxidation process as an oxidant, and acetonitrile was used as a solvent extraction. Box-Behnken experimental design was adopted in the current study to examine oxidation desulfurization by non-thermal plasma for the various operation conditions including time, flow rate, and temperature on sulfur removal efficiency. Acetonitrile with an oxidized oil/solvent ratio of 1:1(v/v ratio) was utilized as the extraction solvent. The results showed that the maximum sulfur removal of about 91% was obtained with a temperature of 50°C, flow rate of 75 ml/min, and time of 4 hours.
Removal of Copper and Zinc Metal Ions from Industrial Effluents in Continuous Mode using Modified Date Pits
Authors: Mohsen Huda A. , Ghanim Alaa N. 
Published: June 2024

Adsorbents based on agricultural biomass have been subjected to several investigations in recent years owing to their low cost and promising adsorption capabilities. This paper aimed to demonstrate the efficiency of utilizing date pits modified with hydrogen peroxide as agricultural biomass in extracting heavy metals from polluted water in a column continuous flow system. The resulting modified adsorbent (MDP) has a surface area of 278.18 m2/g. The derived adsorbent was investigated under changed operating parameters including the flow rate (4-12) ml/min, pH (4-10), initial metal ion concentration (30-60) mg/L, and temperature (20-50) °C to determine their effect on heavy metals adsorption efficiency. The response surface methodology (RSM) experimental design was utilized to study the primary and combined influence of four key parameters, including (A) initial metal ion concentration, (B) pH solution, (C) solution temperature, and (D) flow rates of the influent, on the metal removing efficiency (Re%). optimization in fact, an analysis of variance (ANOVA) revealed a high coefficient of regression, or R2 > 0.90. Furthermore, the removal efficiency was positively influenced by reducing the initial ion concentration, flow rate, and temperature. in addition, the pH shows maximum effectiveness at a neutral state. In general, Cu (II) adsorption shows a higher affinity to adsorb over the MDP surface compared to Zn (II). The MDP adsorbents exhibited a promising removal efficiency for metal ions and further investigations are needed.
Perencanaan Bangunan Tempat Pembuangan Sementara Sampah Di Kelurahan Talang Jawa Kecamatan Baturaja Barat
Authors: Putri Yuliantini Eka , Desromi Ferry , Kartikasari Enda 
Published: June 2024

Kabupaten OKU terbagi dalam 13 kecamatan yang terdiri dari 14 Kelurahan dan 143 Desa, dengan salah satu kelurahannya yaitu kelurahan Talang Jawa yang merupakan salah satu kelurahan terpadat di Kecamatan Baturaja Barat, dengan jumlah penduduk 7332 jiwa dengan kepadatan penduduk 642 per km2 (BPS OKU, 2021). Dengan jumlah masyarakat sebesar itu, maka timbulan sampah yang akan dihasilkan besar pula dan Kelurahan Talang Jawa belum memiliki Tempat Pembuangan Sampah (TPS). Karna tidak adanya Tempat Pembuangan Sampah inilah yang menjadi dasar dari penelitian ini, Selama ini Sampah itumpuk di tanah kosong milik desa yang berada ditepi jalan raya. Tahun perencanaan dalam penelitian ini adalah 5 tahun (2023-2027). Untuk menghitung pertumbuhan penduduk 5 tahun yang akan datang, digunakan metode Aritmatik didapatkan jumlah penduduk Kelurahan Talang Jawa adalah 2213 KK,dengan laju pertambahan penduduk 1,39 % pertahun, dan jumlah timbulan sampah yang dihasilkan sebanyak 27,663 m3/hari. Dari data yang didapat maka timbulan sampah yang dihailkan pertahun sebanyak 10.096,995 m3/tahun. Dari analisa data yang dilakukan dengan memperhitungkan laju pertumbuhan penduduk yang menimbulkan sampah didapatkan bahwa komposisi sampah yang akan digunakan di TPS 3R yang akan direncanakan ini, yaitu sampah organik yang terdiri dari 12% sampah sisa sayuran dan buah, 18% sampah kebun berupa daun-daun kering, dan kertas 32%. sampah anorganik terdiri dari 25% plastik, dan besi/logam 12% serta sampah B3 sebanyak 1%. Total luas lahan untuk perencanaan TPS 3R di kelurahan Talang Jawa adalah seluas 396, 75 m2.
UPAYA PENINGKATAN KOMPETENSI SOSIAL EMOSIONAL SUBTEMA AKU AGGOTA PRAMUKA MELALUI PROJECT BASED LEARNING KELAS 3
Authors: Ashfiyah Siti 
Published: June 2024

Penelitian ini bertujuan untuk mengetahui 1) apakah peningkatan kompetensi sosial emosional subtema aku anggota pramuka dapat diupayakan melalui project based learning (PjBL) peserta didik kelas 3, dan 2) bagaimana langkah-langkah PjBL yang dapat meningkatkan kompetensi sosial emosional subtema aku anggota pramuka peserta didik kelas 3. Subyek penelitian ini adalah seluruh peserta didik kelas 3 SD Negeri Sidorejo Lor Salatiga tahun pelajaran 2022/2023 sebanyak 28 peserta didik yang terdiri dari 15 laki-laki dan 13 perempuan. Jenis penelitian berupa penelitian tindakan kelas (PTK). Model penelitian dari Kemmis dan Mc. Taggart. Prosedur penelitian terdiri dari 2 siklus, masing-masing siklus terdiri dari tiga tahap yaitu: tahap perencanaan, tahap pelaksanaan dan pengamatan dan tahap refleksi. Teknik pengumpulan data menggunakan non tes berupa observasi dan angket. Instrumen penelitian berupa lembar observasi dan butir penyataan. Teknik analisis data adalah teknik kuantitatif komparatif berupa persentase. Hasil penelitian menunjukkan bahwa peningkatan kompetensi sosial emosional tema praja muda karana dapat diupayakan melalui PjBL peserta didik kelas 3. Kriteria baik sekali dapat dilihat dengan ketercapaian 36% dari 28 peserta didik saat prasiklus dan siklus 1 meningkat menjadi 61% dari 28 peserta didik dan siklus 2 menjadi 82% dari 28 peserta didik. Peningkatan kompetensi sosial emosional tema praja muda karana peserta didik kelas 3 dapat diupayakan melalui PjBL dengan langkah-langkah: 1) membuat pertanyaan mendasar dari tema 8 praja muda karana, 2) merancang rencana proyek membuat puzzle lambang negara dan lambang pramuka, 3) membuat jadwal pelaksanaan proyek pembuatan puzzle, 4) pemantauan aktivitas pembuatan puzzle, 5) penilaian puzzle, 6) mengevaluasi kegiatan dan hasil proyek.
Profitabilitas Memoderasi Good Corporate Governance Dan Nilai Perusahaan Perbankan Di Bursa Efek Indonesia
Authors: Dewi Putu Pande R. Aprilyani , Indraswari I Gusti Agung Ayu Pramita 
Published: June 2024

Good company value can be said to be an illustration that the company is able to guarantee prosperity and provide welfare for its shareholders. By implementing good corporate governance, it is hoped that the company will be more transparent and careful in managing the company so that it can be more efficient in carrying out its duties to increase company profits and maximize company value. The research was conducted at banking companies listed on the Indonesia Stock Exchange in 2019-2021. Where the population of this study was 46 companies and the sample was determined using purposive sampling so that a sample size of 60 banking companies was obtained. The results of this research show that good corporate governance has no effect on company value, while profitability strengthens the influence of good corporate governance on company value.
Keyword: good corporate governance, company value, profitability
Revolução digital, desinformação e democracia: a contribuição de Karl Jaspers
Authors: De Marins Nivaldo 
Published: June 2024

A revolução digital cresce a uma velocidade vertiginosa. A base dessa revolução é o paradigma técnico-económico, porém com novos instrumentos. Instrumentos que alcançam um nível planetário e influenciam a relação da nossa personalidade com o mundo. A desinformação é o rastilho de pólvora para a emergência, crescimento e disseminação de conceções racistas e xeno fóbicas. Essa mudança põe em causa valores democráticos. A desinformação alimenta as massas. Veremos como as massas se formam, suas características e seu potencial nefasto de ação. Necessitamos entender os mecanismos de como isso ocorre, os novos instrumentos utilizados, a conexão entre as fontes de informação, os caminhos que vão da persuasão das ideias a imposição dos atos. Enfim, iremos defender um posicionamento frente a absolutização da desinformação dentro do arcabouço democrático. Lançaremos mão do conceito de “Aparatus” utilizado por Karl Jaspers, em meados do seculo passado, como uma forma paralela com pontos de contato para nossa situação atual. Demonstraremos a força, influência da desinformação sobre as massas que se aglutinam e agem a partir do simples toque do celular nos dias que vivemos. Expressaremos, no final, que tal movimento põe em risco o nosso viver democrático e como devemos fazer frente a essa ameaça.
Medical Nutrition Therapy in Hospitalized Pulmonary Tuberculosis Patients: A Retrospective Analysis of Its Effect on Monocyte-to-Lymphocyte Ratio (MLR), Neutrophil-to-Lymphocyte Ratio (NLR), and Prognostic Nutritional Index (PNI)
Authors: Aminuddin Aminuddin , Patunru Urfa , As'ad Suryani , Syauki Andi Yasmin , Bukhari Agussalim , Taslim Nurpudji Astuti 
Published: June 2024

INTRODUCTION: The management of malnutrition plays a pivotal role in the treatment of pulmonary tuberculosis. Laboratory indices routinely examined such as monocyte-to lymphocyte ratio, neutrophil-to-lymphocyte ratio, and prognostic nutritional index may be of importance to evaluate nutrition intervention and/or overall therapy of in-patient pulmonary tuberculosis.

OBJECTIVE: This study aims to examine the effects of medical nutrition therapy on monocyte-to-lymphocyte ratio, neutrophil-to-lymphocyte ratio and prognostic nutritional index in hospitalized pulmonary tuberculosis patients

METHODS: A retrospective study was conducted on pulmonary TB patients who underwent medical nutrition therapy at Wahidin Sudirohusodo Hospital between 2018 and 2020. Data were collected and extracted from eligible subjects’ medical records for analysis

RESULTS: Out of 418 pulmonary TB patients who were institutionalized in the period, data from 133 subjects who underwent medical nutrition therapy and met inclusion criteria were extracted. All subjects were malnourished either moderately or severely based on Subjective Global Assessment. All subjects showed significant improvement in all three indices namely monocyte-to-lymphocyte ratio, neutrophil-to-lymphocyte ratio, and prognostic nutritional index at the end medical nutrition therapy. Improvement magnitude of monocyte-to-lymphocyte ratio and neutrophil-to-lymphocyte ratio is higher if levels of average energy and protein intake are >1500 kcal and >75 gram, respectively

CONCLUSION: Medical nutrition therapy plays a crucial role in hospitalized pulmonary tuberculosis patients’ clinical improvement as shown by monocyte-to-lymphocyte ratio, neutrophil-to-lymphocyte ratio, and prognostic nutritional index.
Bioética de Paul Ricoeur casos difíceis e reconhecimento da mulher
Authors: Aita Tiellet Claudia , Oliveira dos Santos Ozeli 
Published: June 2024

Ao revisar o conceito de reconhecimento, Paul Ricoeur faz uma crítica acentuada ao modelo cartesiano de sujeito e encontra na articulação entre a teleologia aristotélica, por meio da categoria da solicitude e a deontologia kantiana, por meio da categoria do respeito, a dimensão constitutiva de uma nova reflexão: a petit éthique, que na obra O Justo 2 modela uma bioética arrojada, réplica singular a problemas decorrentes do universalismo, da cultura machista, ambos “cegos” à discriminação da mulher. Nossa proposta se consubstancia na ideia de que a bioética ricoeuriana, a partir da análise de um caso difícil de vida começando [aborto] é garantia do reconhecimento da mulher para além da tradição homogeneizadora.

Palavras-chave: Ricoeur; Mulher; Reconhecimento; Bioética.