bluuebunny/crossref_metadata_2025_split huggingface dataset:
The mineral prospecting expeditions to the South Atlantic islands and Antarctic Peninsula region made by the Scottish geologist David Ferguson, 1912–1914
Authors: Stone P. , Faithfull J. 
Published: July 2013

Synopsis
David Ferguson’s mineral prospecting expeditions to South Georgia (1912), the Falkland Islands and the South Shetland Islands (1913–1914), on behalf of the Christian Salvesen whaling company of Leith and now largely forgotten, were early examples of commercially motivated terrestrial exploration in the South Atlantic region. Prior geological knowledge was very limited and Ferguson complemented his unsuccessful prospecting work with attempts to understand the regional geology of the areas that he visited. These interpretations were based on relatively cursory fieldwork undertaken in an arduous environment, and did not prove robust; but the well-documented specimen collections that Ferguson accumulated provided the basis for excellent and much-cited petrographical accounts by G. W. Tyrrell of Glasgow University. Ferguson had studied geology at the university and the influence of his mentor there, Professor J. W. Gregory, is apparent. In turn, Gregory utilized Ferguson’s observations in support of a subsided ‘South Atlantic continent’, opposing the ‘displacement hypothesis’ for that region formalized by Alfred Wegener from 1912 onwards. Ferguson’s field notebooks and most of his rock specimens are now held by Glasgow University (Archive Services and Hunterian Museum, respectively) but he distributed representative specimen collections widely, and these are extant in several other British museums. Specimens were also supplied to, and discussed with, William Speirs Bruce who, following the 1902–1904 Scottish National Antarctic Expedition, took a keen interest in Ferguson’s discoveries.
Detrital monazite geochronology, Upper Jurassic–Lower Cretaceous of the Scotian Basin: significance for tracking first-cycle sources
Authors: Pe-Piper Georgia , Piper David J. W. , Triantafyllidis S. 
Published: July 2013

Abstract
Monazite geochronology was applied to an east–west transect of latest Jurassic and Lower Cretaceous deltaic sandstones of the Scotian Basin, to assess sediment sources and dispersal pathways. More than 200 detrital monazite grains yielded 694 electron microprobe age determinations with 1σ errors <±20%. Based on age, external morphology, zoning, inclusions and major element chemistry (rare earth element [REE], Th, Y), monazite grains represent more than 20 discrete sources. Similar proportions of euhedral and subhedral compared with irregular and rounded monazite grains in most age classes, together with comparison with detrital muscovite and zircon geochronology, suggest that most monazite is first cycle. Six types of REE distribution are recognized (A–F). Many igneous monazites show chemical zoning, contain sparse euhedral inclusions, and have REE distributions of types A and E. Many metamorphic monazites contain inclusions, commonly aligned, are generally rounded–subhedral to rounded, and have REE distributions of types B, C and D. Monazite geochronology shows important supply to the Scotian Basin from the Labrador rift shoulder as early as Tithonian; from Avalonian sources in the Tithonian; from Ordovician sources in northern New Brunswick, apparently via the Chaswood River; and from the inner continental shelf, particularly in the Hauterivian–Barremian.
Tying catchment to basin in a giant sediment routing system: a source-to-sink study of the Neogene–Recent Amur River and its delta in the North Sakhalin Basin
Authors: Nicholson Uisdean , Poynter Sarah , Clift Peter D. , Macdonald David I. M. 
Published: July 2013

Abstract
This paper uses an extensive dataset from more than 200 samples to provide a comprehensive source-to-sink analysis of the Amur River and its delta in the Russian Far East. The majority of sand-sized sediment in the Amur River and its former delta comes from upstream of the Lesser Khingan Ridge, shown by uniformity of sediment composition in the lower 1700 km of the river. Stable mineral ratios, U–Pb age spectra and garnet geochemistry show little stratigraphic provenance-specific variation in the Neogene delta. This renders Miocene–Pliocene drainage capture models unlikely.
The onset of uplift in the delta is marked by a decrease in the apatite–tourmaline index (ATi) in Upper Pliocene offshore well samples, caused by dissolution of apatite as sediments were uplifted and eroded onshore Sakhalin. These wells also show variable ATi and garnet–zircon index (GZi) values in Lower Miocene samples, which could potentially be used for stratigraphic correlation.
A positive correlation between GZi values and distance from the river mouth is attributed to hydrodynamic sorting across the delta system. This has negative implications for the use of this stable mineral index and others of a similar hydraulic equivalence as regional correlation tools on a basin scale (>100 km).

Supplementary material:

Heavy mineral data, petrographic data, geochronometric data, sample locations available at
www.geolsoc.org.uk/SUP18643
.
Dynamic element textures
Authors: Ma Chongyang , Wei Li-Yi , Lefebvre Sylvain , Tong Xin 
Published: July 2013

Many natural phenomena consist of geometric elements with dynamic motions characterized by small scale repetitions over large scale structures, such as particles, herds, threads, and sheets. Due to their ubiquity, controlling the appearance and behavior of such phenomena is important for a variety of graphics applications. However, such control is often challenging; the repetitive elements are often too numerous for manual edit, while their overall structures are often too versatile for fully automatic computation.
We propose a method that facilitates easy and intuitive controls at both scales: high-level structures through spatial-temporal output constraints (e.g. overall shape and motion of the output domain), and low-level details through small input exemplars (e.g. element arrangements and movements). These controls are suitable for manual specification, while the corresponding geometric and dynamic repetitions are suitable for automatic computation. Our system takes such user controls as inputs, and generates as outputs the corresponding repetitions satisfying the controls.

Our method, which we call
dynamic element textures
, aims to produce such controllable repetitions through a combination of constrained optimization (satisfying controls) and data driven computation (synthesizing details). We use spatial-temporal samples as the core representation for dynamic geometric elements. We propose analysis algorithms for decomposing small scale repetitions from large scale themes, as well as synthesis algorithms for generating outputs satisfying user controls. Our method is general, producing a range of artistic effects that previously required disparate and specialized techniques.
Low-budget transient imaging using photonic mixer devices
Authors: Heide Felix , Hullin Matthias B. , Gregson James , Heidrich Wolfgang 
Published: July 2013

Transient imaging is an exciting a new imaging modality that can be used to understand light propagation in complex environments, and to capture and analyze scene properties such as the shape of hidden objects or the reflectance properties of surfaces.
Unfortunately, research in transient imaging has so far been hindered by the high cost of the required instrumentation, as well as the fragility and difficulty to operate and calibrate devices such as femtosecond lasers and streak cameras.
In this paper, we explore the use of photonic mixer devices (PMD), commonly used in inexpensive time-of-flight cameras, as alternative instrumentation for transient imaging. We obtain a sequence of differently modulated images with a PMD sensor, impose a model for local light/object interaction, and use an optimization procedure to infer transient images given the measurements and model. The resulting method produces transient images at a cost several orders of magnitude below existing methods, while simultaneously simplifying and speeding up the capture process.
UML behavioral model based test case generation
Authors: Shirole Mahesh , Kumar Rajeev 
Published: July 2013

In software engineering, system modeling is the process of formulating a representation of a real system in an abstract way to understand its behavior. Software testing encourages reusing these models for testing purpose. This expedites the process of test case generation. UML structural and behavioral specification diagrams have been used by testing researchers for generation of test scenarios and test data.
The aim of this survey is to improve the understanding of UML based testing techniques. We have focused on test case generation from the behavioral specification diagrams, namely sequence, state chart and activity diagrams. We classify the various research approaches that are based on formal specifications, graph theoretic, heuristic testing, and direct UML specification processing. We discuss the issues of test coverage associated with these approaches.
OOPSLA 2002
Authors: Berger Emery D. , Zorn Benjamin G. , McKinley Kathryn S. 
Published: July 2013

Programmers hoping to achieve performance improvements often use custom memory allocators. This in-depth study examines eight applications that use custom allocators. Surprisingly, for six of these applications, a state-of-the-art general-purpose allocator (the Lea allocator) performs as well as or better than the custom allocators. The two exceptions use regions, which deliver higher performance (improvements of up to 44%). Regions also reduce programmer burden and eliminate a source of memory leaks. However, we show that the inability of programmers to free individual objects within regions can lead to a substantial increase in memory consumption. Worse, this limitation precludes the use of regions for common programming idioms, reducing their usefulness.
We present a generalization of general-purpose and region-based allocators that we call reaps. Reaps are a combination of regions and heaps, providing a full range of region semantics with the addition of individual object deletion. We show that our implementation of reaps provides high performance, outperforming other allocators with region-like semantics. We then use a case study to demonstrate the space advantages and software engineering benefits of reaps in practice. Our results indicate that programmers needing fast regions should use reaps, and that most programmers considering custom allocators should instead use the Lea allocator.
Lamin B1 Is a Novel Therapeutic Target of Betulinic Acid in Pancreatic Cancer
Authors: Li Lei , Du Yiqi , Kong Xiangyu , Li Zhaoshen , Jia Zhiliang , Cui Jiujie , Gao Jun , Wang Guokun , Xie Keping 
Published: July 2013

Abstract
Purpose: Betulinic acid, a naturally occurring pentacyclic triterpenoid, exhibits potent antitumor activities, whereas the underlying mechanisms remain unclear. In the current study, we sought to determine the role and regulation of lamin B1 expression in human pancreatic cancer pathogenesis and betulinic acid–based therapy.
Experimental Design: We used cDNA microarray to identify betulinic acid target genes and used tissue microarray to determine the expression levels of lamin B1 in pancreatic cancer tissues and to define their relationship with the clinicopathologic characteristics of pancreatic cancer. We also used in vitro and in vivo models to determine the biologic impacts of altered lamin B1 expression on and mechanisms underlying lamin B1 overexpression in human pancreatic cancer.
Results: We found that lamin B1 was significantly downregulated by betulinic acid treatment in pancreatic cancer in both in vitro culture and xenograft models. Overexpression of lamin B1 was pronounced in human pancreatic cancer, and increased lamin B1 expression was directly associated with low-grade differentiation, increased incidence of distant metastasis, and poor prognosis of patients with pancreatic cancer. Furthermore, knockdown of lamin B1 significantly attenuated the proliferation, invasion, and tumorigenicity of pancreatic cancer cells.
Conclusions: Lamin B1 plays an important role in pancreatic cancer pathogenesis and is a novel therapeutic target of betulinic acid treatment. Clin Cancer Res; 19(17); 4651–61. ©2013 AACR.
Identification of a
KCNQ1
Polymorphism Acting as a Protective Modifier Against Arrhythmic Risk in Long-QT Syndrome
Authors: Duchatelet Sabine , Crotti Lia , Peat Rachel A. , Denjoy Isabelle , Itoh Hideki , Berthet Myriam , Ohno Seiko , Fressart Véronique , Monti Maria Cristina , Crocamo Cristina , Pedrazzini Matteo , Dagradi Federica , Vicentini Alessandro , Klug Didier , Brink Paul A. , Goosen Althea , Swan Heikki , Toivonen Lauri , Lahtinen Annukka M. , Kontula Kimmo , Shimizu Wataru , Horie Minoru , George Alfred L. , Trégouët David-Alexandre , Guicheney Pascale , Schwartz Peter J. 
Published: July 2013

Background—
Long-QT syndrome (LQTS) is characterized by such striking clinical heterogeneity that, even among family members carrying the same mutation, clinical outcome can range between sudden death and no symptoms. We investigated the role of genetic variants as modifiers of risk for cardiac events in patients with LQTS.

Methods and Results—

In a matched case–control study including 112 patient duos with LQTS from France, Italy, and Japan, 25 polymorphisms were genotyped based on either their association with QTc duration in healthy populations or on their role in adrenergic responses. The duos were composed of 2 relatives harboring the same heterozygous
KCNQ1
or
KCNH2
mutation: 1 with cardiac events and 1 asymptomatic and untreated. The findings were then validated in 2 independent founder populations totaling 174 symptomatic and 162 asymptomatic patients with LQTS, and a meta-analysis was performed. The
KCNQ1
rs2074238 T-allele was significantly associated with a decreased risk of symptoms 0.34 (0.19–0.61;
P
<0.0002) and with shorter QTc (
P
<0.0001) in the combined discovery and replication cohorts.

Conclusions—

We provide evidence that the
KCNQ1
rs2074238 polymorphism is an independent risk modifier with the minor T-allele conferring protection against cardiac events in patients with LQTS. This finding is a step toward a novel approach for risk stratification in patients with LQTS.
Hospital Strategies Associated With 30-Day Readmission Rates for Patients With Heart Failure
Authors: Bradley Elizabeth H. , Curry Leslie , Horwitz Leora I. , Sipsma Heather , Wang Yongfei , Walsh Mary Norine , Goldmann Don , White Neal , Piña Ileana L. , Krumholz Harlan M. 
Published: July 2013

Background—
Reducing hospital readmission rates is a national priority; however, evidence about hospital strategies that are associated with lower readmission rates is limited. We sought to identify hospital strategies that were associated with lower readmission rates for patients with heart failure.

Methods and Results—

Using data from a Web-based survey of hospitals participating in national quality initiatives to reduce readmission (n=599; 91% response rate) during 2010–2011, we constructed a multivariable linear regression model, weighted by hospital volume, to determine strategies independently associated with risk-standardized 30-day readmission rates (RSRRs) adjusted for hospital teaching status, geographic location, and number of staffed beds. Strategies that were associated with lower hospital RSRRs included the following: (1) partnering with community physicians or physician groups to reduce readmission (0.33% percentage point lower RSRRs;
P
=0.017), (2) partnering with local hospitals to reduce readmissions (0.34 percentage point;
P
=0.020), (3) having nurses responsible for medication reconciliation (0.18 percentage point;
P
=0.002), (4) arranging follow-up appointments before discharge (0.19 percentage point;
P
=0.037), (5) having a process in place to send all discharge paper or electronic summaries directly to the patient’s primary physician (0.21 percentage point;
P
=0.004), and (6) assigning staff to follow up on test results that return after the patient is discharged (0.26 percentage point;
P
=0.049). Although statistically significant, the magnitude of the effects was modest with individual strategies associated with less than half a percentage point reduction in RSRRs; however, hospitals that implemented more strategies had significantly lower RSRRs (reduction of 0.34 percentage point for each additional strategy).

Conclusions—
Several strategies were associated with lower hospital RSRRs for patients with heart failure.
Disruption of Visual Awareness during the Attentional Blink Is Reflected by Selective Disruption of Late-stage Neural Processing
Authors: Harris Joseph A. , McMahon Alex R. , Woldorff Marty G. 
Published: July 2013

Abstract
Any information represented in the brain holds the potential to influence behavior. It is therefore of broad interest to determine the extent and quality of neural processing of stimulus input that occurs with and without awareness. The attentional blink is a useful tool for dissociating neural and behavioral measures of perceptual visual processing across conditions of awareness. The extent of higher-order visual information beyond basic sensory signaling that is processed during the attentional blink remains controversial. To determine what neural processing at the level of visual-object categorization occurs in the absence of awareness, electrophysiological responses to images of faces and houses were recorded both within and outside the attentional blink period during a rapid serial visual presentation stream. Electrophysiological results were sorted according to behavioral performance (correctly identified targets vs. missed targets) within these blink and nonblink periods. An early index of face-specific processing (the N170, 140- to 220-msec poststimulus) was observed regardless of whether the participant demonstrated awareness of the stimulus, whereas a later face-specific effect with the same topographic distribution (500- to 700-msec poststimulus) was only seen for accurate behavioral discrimination of the stimulus content. The present findings suggest a multistage process of object-category processing, with only the later phase being associated with explicit visual awareness.
Perceptual Sequence Learning Is More Severely Impaired than Motor Sequence Learning in Patients with Chronic Cerebellar Stroke
Authors: Dirnberger Georg , Novak Judith , Nasel Christian 
Published: July 2013

Abstract
Patients with cerebellar stroke are impaired in procedural learning. Several different learning mechanisms contribute to procedural learning in healthy individuals. The aim was to compare the relative share of different learning mechanisms in patients and healthy controls. Ten patients with cerebellar stroke and 12 healthy controls practiced a visuomotor serial reaction time task. Learning blocks with high stimulus–response compatibility were exercised repeatedly; in between these, participants performed test blocks with the same or a different (mirror-inverted or unrelated) stimulus sequence and/or the same or a different (mirror-inverted) stimulus–response allocation. This design allowed to measure the impact of motor learning and perceptual learning independently and to separate both mechanisms from the learning of stimulus–response pairs. Analysis of the learning blocks showed that, as expected, both patients and controls improved their performance over time, although patients remained significantly slower. Analysis of the test blocks revealed that controls showed significant motor learning as well as significant visual perceptual learning, whereas cerebellar patients showed only significant motor learning. Healthy participants were able to use perceptual information for procedural learning even when the rule linking stimuli and responses had been changed, whereas patients with cerebellar lesions could not recruit this perception-based mechanism. Therefore, the cerebellum appears involved in the accurate processing of perceptual information independent from prelearned stimulus–response mappings.
A Study of Nocturnal Surface Wind Speed Overprediction by the WRF-ARW Model in Southeastern Texas
Authors: Ngan Fong , Kim Hyuncheol , Lee Pius , Al-Wali Khalid , Dornblaser Bright 
Published: July 2013

AbstractThe overprediction of surface wind speed during nighttime by the Advanced Research core of the Weather Research and Forecasting (WRF-ARW) model was investigated for a period of the Second Texas Air Quality Study (28 May–3 July 2006). In coastal regions of southeastern Texas, the model had a significant increase of wind speed biases on the surface in the evening throughout the period, especially between 4 and 12 June. The synoptic pattern was a high pressure system centered over the Louisiana–Mississippi area that was subjected to a weak easterly–southeasterly flow in the lower troposphere. The weather conditions favorable for sea-breeze development brought a southerly–southwesterly onshore flow to the near-surface levels. In comparison with measurements, the downward sensible heat flux was overpredicted at night, which resulted in a warm bias in surface temperature. For the vertical wind profile on days with an evening wind bias, sea-breeze-driven nocturnal low-level jets (southerly–southwesterly) were present at around 300 m while another wind maximum was observed at higher levels (around 1.5–2 km), which were associated with a high pressure system centered on southeastern states. The vertical gradient of wind speed in the lowest 150 m was smoother in the model than it was in the observations; this could be attributed to excessive downward mixing. Sensitivities using different land surface and PBL parameterizations showed that the model's overprediction of nocturnal wind was still present despite improvements in the predictions of surface temperature and sensible heat flux.
An Analysis of Loop Current Frontal Eddies in a ⅙° Atlantic Ocean Model Simulation
Authors: Huang Haosheng , Walker Nan D. , Hsueh Ya , Chao Yi , Leben Robert R. 
Published: July 2013

Abstract
The Loop Current frontal eddies (LCFEs) refer to cyclonic cold eddies moving downstream along the outside edge of the Loop Current in the eastern Gulf of Mexico. They have been observed by in situ measurements and satellite imagery, mostly downstream of the Campeche Bank continental shelf. Their evolution, simulated by a primitive equation ⅙° and 37-level Atlantic Ocean general circulation numerical model, is described in detail in this study. Some of the simulated LCFEs arise, with the passage through the Yucatan Channel of a Caribbean anticyclonic eddy, as weak cyclones with diameters less than 100 km near the Yucatan Channel. They then grow to fully developed eddies with diameters on the order of 150–200 km while moving along the Loop Current edge. Modeled LCFEs have a very coherent vertical structure with isotherm doming seen from 50- to ~1000-m depth. The Caribbean anticyclone and LCFE are two predominant features in this numerical model simulation, which account for 22% and 10%, respectively, of the short-term (period less than 100 days) temperature variance at 104.5 m in the complex empirical orthogonal function (CEOF) analysis. The source water inside the LCFEs that are generated by Caribbean anticyclonic eddy impingement can be traced back, using a backward-in-time Lagrangian particle-tracking method, to the western edge of the Caribbean Current in the northwest Caribbean Sea and to coastal waters near the northern Yucatan Peninsula. The model results indicating a pairing of anticyclonic and cyclonic eddies within and north of the Yucatan Channel are supported by satellite altimetry measurements during February 2002 when several altimeters were operational.