bluuebunny/crossref_metadata_2025_split huggingface dataset:
Seismic geologic structure model for the sedimentary cover of the Laptev Sea part of the Lomonosov Ridge and adjacent parts of the Amundsen Plain and Podvodnikov Basin
Authors: Rekant P.V. , Gusev E.A. 
Published: October 2012

Abstract
Seismic data on the southern (Laptev Sea) extremity of the Lomonosov Ridge were used to develop a new structural model for the sedimentary cover. It permitted a correlation between the seismic cross-sections of the ridge crest and two deep-sea basins: the Podvodnikov Basin and the Amundsen Plain. It is the first time that a seismic model has taken into account both regional seismic-reflection profiles obtained from NP drifting ice stations and recent high-resolution CDP data. Our seismic model agrees both with geological data on the Laptev Sea continental margin and the data obtained from deep-sea drilling into the Lomonosov Ridge under the IODP-302 project. The sedimentary cover of the southern Lomonosov Ridge and adjacent parts of the Amundsen Plain and Podvodnikov Basin was dated at the Aptian–Cenozoic. The sedimentary section is divided by two main unconformities, of Campanian–Paleocene and Oligocene–Early Miocene ages. The cover contains a structurally complicated graben system, which is an extension of the New Siberian system of horsts and grabens, recognized in the shelf. Sedimentation began in the grabens in the Aptian–Albian and ended with their complete compensation in the Paleocene.
Neoproterozoic alkaline magmatism and associated igneous rocks in the western framing of the Siberian craton: petrography, geochemistry, and geochronology
Authors: Romanova I.V. , Vernikovskaya A.E. , Vernikovsky V.A. , Matushkin N.Yu. , Larionov A.N. 
Published: October 2012

Abstract
The formation and evolution conditions for alkaline magmatism and associated igneous rocks in the western framing of the Siberian craton are shown by the example of alkaline and subalkaline intrusive bodies of the Yenisei Ridge. Here we present petrographic, mineralogical, geochemical, and geochronological data for the rocks of the Srednetatarka and Yagodka plutons located within the Tatarka–Ishimba suture zone. Ferroan and metaluminous varieties enriched with rare elements (Nb, Ta, Zr, Hf, and REE) are making up most of the studied rocks. They formed at the stages of fractional crystallization of alkaline magma in a setting of active continental margin in the west of the Siberian craton in the Late Neoproterozoic (710–690 Ma). As differentiates of mantle magmas, these rocks associate with Nb-enriched rocks—A-type leucogranites and carbonatites. Sm/Nd and Rb/Sr isotopic data imply a predominance of the mantle component in the magmatic sources of the mafic and intermediate rocks as well as contamination processes of various volumes of continental crustal material by this magma.
Paleomagnetism of trap basalts in the northwestern Siberian craton, from core data
Authors: Mikhaltsov N.E. , Kazansky A.Yu. , Ryabov V.V. , Shevko A.Ya. , Kuprish O.V. , Bragin V.Yu. 
Published: October 2012

Abstract
We present new paleomagnetic data for continental flood basalts (Siberian traps) obtained from cores of two boreholes in the northwestern Noril’sk area, within the Kharaelakh and Vologochan basins. Paleomagnetic measurements of lava and tuff samples from KhS-59 and SSV-19 boreholes allowed reconstructing and correlating the polarity patterns. Thus multiple paleomagnetic anomalies (PMA) have been discovered as brief polarity changes in narrow intervals of the magnetostratigraphic section above the principle reversal at the boundary between the Ivakin and Syverma Formations.
The most prominent anomalies are observed at the bases of the Morongo and Mokulai Formations. The samples from the anomalous intervals differ from those of other intervals neither in rock magnetic properties, nor in mineralogy and magnetic grain sizes. Therefore, the revealed PMA record excursions of the geomagnetic field. Comparison of the results with the Meishan Global Stratotype Section and Point (GSSP) of the Permian–Triassic boundary implies a revision to the P–T position in the trap basalt succession of the Noril’sk area. Judging by the EMF behavior, basalts in this part of the trap province erupted for at least 500 kyr during an interval of stable normal polarity.
Management of High Altitude Pulmonary Edema in the Himalaya: A Review of 56 Cases Presenting at Pheriche Medical Aid Post (4240 m)
Authors: Jones Barbara E. , Stokes Suzy , McKenzie Suzi , Nilles Eric , Stoddard Gregory J. 
Published: October 2012

Objective The purpose of this study was to review the patient characteristics and management of 56 cases of high altitude pulmonary edema at the Pheriche Himalayan Rescue Association Medical Aid Post, and to measure the use of medications in addition to descent and oxygen. Methods In a retrospective case series, we reviewed all patients diagnosed clinically with high altitude pulmonary edema during the 2010 Spring and Fall seasons. Nationality, altitude at onset of symptoms, physical examination findings, therapies administered, and evacuation methods were evaluated. Results Of all patients, 23% were Nepalese, with no difference in clinical features compared with non-Nepalese patients; 28% of all patients were also suspected of having high altitude cerebral edema. Symptoms developed in 91% of all patients at an altitude higher than the aid post (median altitude of onset of 4834 m); 83% received oxygen therapy, and 87% received nifedipine, 44% sildenafil, 32% dexamethasone, and 39% acetazolamide. Patients who were administered sildenafil, dexamethasone, or acetazolamide had presented with significantly lower initial oxygen saturations ( P ≤ .05). After treatment, 93% of all patients descended; 38% descended on foot without a supply of oxygen. Conclusions A significant number of patients presenting to the Pheriche medical aid post with high altitude pulmonary edema were given dexamethasone, sildenafil, or acetazolamide in addition to oxygen, nifedipine, and descent. This finding may be related to perceived severity of illness and evacuation limitations. Although no adverse effects were observed, the use of multiple medications is not supported by current evidence and should not be widely adopted without further study.
Identifying recommended dietary allowances for protein and amino acids: a critique of the 2007 WHO/FAO/UNU report
Authors: Millward D. Joe 
Published: October 2012

The WHO/FAO/UNU (2007) report examines dietary protein and amino acid requirements for all age groups, protein requirements during pregnancy, lactation and catch-up growth in children, the implications of these requirements for developing countries and protein quality evaluation. Requirements were defined as the minimum dietary intake which satisfies the metabolic demand and achieves nitrogen equilibrium and maintenance of the body protein mass, plus the needs for growth in children and pregnancy and lactation in healthy women. Insufficient evidence was identified to enable recommendations for specific health outcomes. A meta analysis of nitrogen balance studies identifies protein requirements for adults 10 % higher than previous values with no influence of gender or age, consistent with a subsequently published comprehensive study. A new factorial model for infants and children, validated on the basis of the adequacy of breast milk protein intakes and involving a lower maintenance requirement value, no provision for saltatory growth and new estimates of protein deposition identifies lower protein requirements than in previous reports. Higher values for adult amino acid requirements, derived from a re-evaluation of nitrogen balance studies and new stable isotope studies, identify some cereal-based diets as being inadequate for lysine. The main outstanding issues relate to the biological implausibility of the very low efficiencies of protein utilisation used in the factorial models for protein requirements for all population groups especially pregnancy when requirements may be overestimated. Also considerable uncertainty remains about the design and interpretation of most of the studies used to identify amino acid requirement values.
Advantages and limitations of the protein digestibility-corrected amino acid score (PDCAAS) as a method for evaluating protein quality in human diets
Authors: Schaafsma Gertjan 
Published: October 2012

PDCAAS is a widely used assay for evaluating protein quality. It is a chemical score, which is derived from the ratio between the first limiting amino acid in a test protein and the corresponding amino acid in a reference amino acid pattern and corrected for true faecal N digestibility. Chemical scores exceeding 100 % are truncated to 100 %. The advantages of the PDCAAS are its simplicity and direct relationship to human protein requirements. The limitations are as follows: the reference pattern is based on the minimum amino acid requirements for tissue growth and maintenance and does not necessarily reflect the optimum intake. Truncated PDCAAS of high-quality proteins do not give any information about the power of these proteins to compensate, as a supplement, for low levels of dietary essential amino acids in low-quality proteins. It is likely that faecal N digestibility does not take into account the loss from the colon of indispensable amino acids that were not absorbed in the ileum. Anti-nutritional factors, such as lectins and trypsin inhibitors, in several plant protein sources can cause heightened endogenous losses of amino acids, an issue which is particularly relevant in animal feedstuffs. The assumption that amino acid supplementation can completely restore biological efficiency of the protein source is incorrect since the kinetics of digestion and absorption between supplemented free amino acids and amino acids present in dietary proteins, are different.
Assessment of protein adequacy in developing countries: quality matters
Authors: Ghosh Shibani , Suri Devika , Uauy Ricardo 
Published: October 2012

Dietary protein and amino acid requirement recommendations for normal “healthy” children and adults have varied considerably with 2007 FAO/WHO protein requirement estimates for children lower, but dietary essential AA requirements for adults more than doubled. Requirement estimates as presented do not account for common living conditions, which are prevalent in developing countries such as energy deficit, infection burden and added functional demands for protein and AAs. This study examined the effect of adjusting total dietary protein for quality and digestibility (PDCAAS) and of correcting current protein and AA requirements for the effect of infection and a mild energy deficit to estimate utilizable protein (total protein corrected for biological value and digestibility) and the risk/prevalence of protein inadequacy. The relationship between utilizable protein/prevalence of protein inadequacy and stunting across regions and countries was examined. Data sources (n = 116 countries) included FAO FBS (food supply), UNICEF (stunting prevalence), UNDP (GDP) and UNSTATS (IMR) and USDA nutrient tables. Statistical analyses included Pearson correlations, paired-sample/non-parametric t-tests and linear regression. Statistically significant differences were observed in risk/prevalence estimates of protein inadequacy using total protein and the current protein requirements versus utilizable protein and the adjusted protein requirements for all regions (p < 0·05). Total protein, utilizable protein, GDP per capita and total energy were each highly correlated with the prevalence of stunting. Energy, protein and utilizable protein availability were independently and negatively associated with stunting (p < 0·001), explaining 41 %, 34 % and 40 % of variation respectively. Controlling for energy, total protein was not a statistically significant factor but utilizable protein remained significant explaining~45 % of the variance (p = 0·017). Dietary utilizable protein provides a better index of population impact of risk/prevalence of protein inadequacy than crude protein intake. We conclude that the increased demand for protein due to infections and mild to moderate energy deficits, should be appropriately considered in assessing needs of populations where those conditions still prevail.
Dietary changes in obese patients undergoing gastric bypass or lifestyle intervention: a clinical trial
Authors: Johnson Line K. , Andersen Lene F. , Hofsø Dag , Aasheim Erlend T. , Holven Kirsten B. , Sandbu Rune , Røislien Jo , Hjelmesæth Jøran 
Published: October 2012

We compared changes in the dietary patterns of morbidly obese patients undergoing either laparoscopic gastric bypass surgery or a comprehensive lifestyle intervention programme. The present 1-year non-randomised controlled trial included fifty-four patients in the lifestyle group and seventy-two in the surgery group. Dietary intake was assessed by a validated FFQ. ANCOVA was used to adjust for between-group differences in sex, age, baseline BMI and baseline values of the dependent variables. Intakes of food groups and nutrients did not differ significantly between the intervention groups at baseline. At 1-year follow-up, the lifestyle group had a significantly higher daily intake of fruits and vegetables (561 (sd 198) v. 441 (sd 213) g, P= 0·002), whole grains (63 (sd 24) v. 49 (sd 16) g, P< 0·001) and fibre (28 (sd 6) v. 22 (sd 6) g, P< 0·001) than the surgery group and a lower percentage of total energy intake of saturated fat (12 (sd 3) v. 14 (sd 3) %, P< 0·001). The intake of red meat declined significantly within both groups, vegetables and fish intake were reduced significantly in the surgery group and added sugar was reduced significantly in the lifestyle group. The lifestyle patients improved their dietary patterns significantly (compared with the surgery group), increasing their intake of vegetables, whole grains and fibre and reducing their percentage intake of saturated fat (ANCOVA, all P< 0·001). In conclusion, lifestyle intervention was associated with more favourable dietary 1-year changes than gastric bypass surgery in morbidly obese patients, as measured by intake of vegetables, whole grains, fibre and saturated fat.
Enigmatic sedimentary structures in the Lower Old Red Sandstone, south Wales, UK: possible microbial influence on surface processes and early terrestrial food webs
Authors: MARRIOTT SUSAN B. , HILLIER ROBERT D. , MORRISSEY LANCE B. 
Published: October 2012

AbstractSeveral enigmatic sedimentary structures are present in Upper Silurian and Lower Devonian terrestrial rocks of south Wales. These are millimetre ripples, wrinkle structures, ‘cauliflower’ and ‘molehill’ structures, calcretized matgrounds, ‘pepper-pots’ and ‘fairy rings’. Most of the structures occur on fine-grained sandstone bedding surfaces in both inclined and non-inclined red heterolithic deposits that form a large part of the Lower Old Red Sandstone in south Wales. These deposits consist of conspicuous units up to 3 m thick, comprising millimetre- to centimetre-scale laminasets of alternating mudstone and fine-grained sandstone, interpreted as muddy point bars on ephemeral channel margins, crevasse-splay lobes or distal flood-out deposits from ephemeral flow. They are rich in trace fossils reflecting animal locomotion, burrowing, foraging, ploughing and resting. Millimetre ripples and wrinkle structures are related to rapid growth of cyanobacterial mats on wet sediment surfaces, especially in films of standing water, that may have been a critical constituent of the food chain for terrestrial communities. Pustular ‘cauliflower’ and ‘molehill’ structures are preserved on tuffs and have been linked to algal blooms formed following an increase in nutrients due to ashfall into floodplain ponds. The tuffs are associated with a diverse ichnofauna indicating that opportunist colonizers took advantage of an abundant food source.
IHL 2.0: Is There a Role for Social Media in Monitoring and Enforcement?
Authors: Herzberg Anne , Steinberg Gerald M 
Published: October 2012

This article will examine the opportunities and limitations of using social media in the execution of legal duties relating to the monitoring and enforcement of IHL. The article will first provide an overview of social media. Next, it will briefly summarise the normative framework of IHL as well as the legal duties of the primary actors and promoters of IHL (for example, states, the UN, NGOs, the International Committee of the Red Cross and courts) to monitor and enforce these rules. The article will then address specific legal obligations relating to IHL monitoring and enforcement and the impact of social media on meeting these requirements.Throughout, the article will use case studies from several conflict zones, including Sudan, Uganda, Mexico, Somalia, Gaza and Libya. The article will conclude that social media can play a critical role in promoting IHL education, and monitoring for potential violations. The benefits of this technology, however, are less clear for carrying out legal obligations related to the enforcement of IHL, such as fact-finding, arrest and prosecution. It is essential, therefore, that clear guidelines for utilising this quickly evolving technology, particularly in official fact-finding and judicial frameworks, be established.
The parasite fauna of the Patagonian toothfish Dissostichus eleginoides off the Falkland Islands
Authors: Brown J. , Brickle P. , Scott B.E. 
Published: October 2012

AbstractThe parasite fauna of juvenile Dissostichus eleginoides, while they inhabit the Falkland's shelf, was examined, giving new detailed information on spatial, ontogenic and seasonal variations. A total of 24,943 parasites from 15 different taxa were found in the stomach of 502 individual fish. Parasite species composition and abundance allowed separation of toothfish by area between the north-west and south-east of the Falklands. The digenean, Elytrophalloides oatesi, and the nematodes, Hysterothylacium spp. and Anisakis spp., were the most common, all with a prevalence >20%. For some seasons ontogenic changes in abundance were significant in these three parasite taxa, and this is discussed in terms of ontogenic and seasonal changes in diet. Elytrophalloides oatesi and Hysterothylacium spp. showed spatial and seasonal differences in abundance with greater numbers in the warmer waters of the north-west and during the summer months. Differences in abundance of E. oatesi between the Falklands and other regions indicate its potential for use as a biological tag to study toothfish movements and population structure; however, more seasonal data would be required before this technique could be used.
Vitamin D, type 2 diabetes and other metabolic outcomes: a systematic review and meta-analysis of prospective studies
Authors: Khan Hassan , Kunutsor Setor , Franco Oscar H. , Chowdhury Rajiv 
Published: October 2012

Vitamin D status may influence the risk of developing metabolic diseases such as Type 2 diabetes (T2D), metabolic syndrome (MetS) and insulin resistance (IR). Several studies have assessed vitamin D in relationship with metabolic outcomes; however, results remain inconsistent. A systematic review and meta-analysis using multiple databases (MEDLINE, Web of Science and EMBASE), was performed up to 10 August 2012. Prospective studies reporting association of circulating or dietary vitamin D with incident T2D, MetS and IR outcomes were included. Relative risks (RR) were pooled using random effects and subgroup analysis by pertinent study-level characteristics was performed. A total of seventeen articles based on eighteen unique prospective studies, and comprising 210 107 participants with 15 899 metabolic events, collected during a median follow up of 10 years (range 3–22 years), were included. RR for individuals in top v. bottom thirds of baseline vitamin D were 0·81 (95% CI 0·71, 0·92); 0·86 (95% CI 0·80, 0·92); and 0·84 (95% CI 0·64, 1·12) for T2D, MetS and IR outcomes, respectively. Moderate heterogeneity was found between fourteen studies (I2 = 67%, P < 0·001) reporting on T2D. Findings were generally consistent across various study-level characteristics. In conclusion, vitamin D status at baseline in apparently healthy adults is inversely associated with future risks of T2D and MetS. Interventions aimed at maintaining adequate levels of vitamin D in addition to preventing deficiency may be a useful preventive measure for metabolic diseases. However, reliable evidence from carefully designed intervention studies, particularly those based on healthy populations, is needed to confirm observational findings.
Intestinal schistosomiasis in chimpanzees on Ngamba Island, Uganda: observations on liver fibrosis, schistosome genetic diversity and praziquantel treatment
Authors: STANDLEY C. J. , MUGISHA L. , ADRIKO M. , ARINAITWE M. , RUKUNDO J. , AJAROVA L. , MOPYA S. , BETSON M. , KABATEREINE N. B. , STOTHARD J. R. 
Published: October 2012

SUMMARYDespite treatment with praziquantel (PZQ) at 40 mg/kg in food, several chimpanzees on Ngamba Island Chimpanzee Sanctuary (NICS) continue to excrete eggs of Schistosoma mansoni. To monitor disease, 8 animals were closely examined under anaesthesia in March 2011 with portable ultrasonography and by rectal snip biopsy. Schistosome genetic diversity had been previously assayed within 4 of these chimpanzees, finding extensive diversity with 27 DNA barcodes encountered, although none was common to all animals. Calcified schistosome eggs were found in the rectal snips from 5 chimpanzees and liver fibrosis was clearly documented, indicative of progressive disease in 6 animals, the latter being surprisingly advanced in a younger chimpanzee. All 8 animals were treated under anaesthesia by oral gavage with PZQ at 60 mg/kg dosing that was well tolerated. These animals were again re-examined in June 2012 using stool and urine sampling. Only 1 chimpanzee appeared to be free from infection and active egg excretion was confirmed in 6 animals. If intestinal schistosomiasis is to be controlled within this setting, a long-term disease management plan is required which should combine active case-detection with an insistent treatment regime with praziquantel for these chimpanzees, exploring perhaps the performance of even higher dosing.
Parasol cell mosaics are unlikely to drive the formation of structured orientation maps in primary visual cortex
Authors: HORE VICTORIA R.A. , TROY JOHN B. , EGLEN STEPHEN J. 
Published: October 2012

AbstractThe receptive fields of on- and off-center parasol cell mosaics independently tile the retina to ensure efficient sampling of visual space. A recent theoretical model represented the on- and off-center mosaics by noisy hexagonal lattices of slightly different density. When the two lattices are overlaid, long-range Moiré interference patterns are generated. These Moiré interference patterns have been suggested to drive the formation of highly structured orientation maps in visual cortex. Here, we show that noisy hexagonal lattices do not capture the spatial statistics of parasol cell mosaics. An alternative model based upon local exclusion zones, termed as the pairwise interaction point process (PIPP) model, generates patterns that are statistically indistinguishable from parasol cell mosaics. A key difference between the PIPP model and the hexagonal lattice model is that the PIPP model does not generate Moiré interference patterns, and hence stimulated orientation maps do not show any hexagonal structure. Finally, we estimate the spatial extent of spatial correlations in parasol cell mosaics to be only 200–350μm, far less than that required to generate Moiré interference. We conclude that parasol cell mosaics are too disordered to drive the formation of highly structured orientation maps in visual cortex.