bluuebunny/crossref_metadata_2025_split huggingface dataset:
Positive Association Between Serum Level of Glyceraldehyde-Derived Advanced Glycation End Products and Vascular Inflammation Evaluated by [18F]Fluorodeoxyglucose Positron Emission Tomography
Authors: Tahara Nobuhiro , Yamagishi Sho-ichi , Takeuchi Masayoshi , Honda Akihiro , Tahara Atsuko , Nitta Yoshikazu , Kodama Norihiro , Mizoguchi Minori , Kaida Hayato , Ishibashi Masatoshi , Hayabuchi Naofumi , Matsui Takanori , Imaizumi Tsutomu 
Published: August 2012

OBJECTIVE
Advanced glycation end products (AGEs) evoke inflammatory reactions, contributing to the development and progression of atherosclerosis. We investigated the relationship between serum AGE level and vascular inflammation.

RESEARCH DESIGN AND METHODS
The study involved 275 outpatients at Kurume University, Japan (189 males and 86 females; mean age 61.2 ± 8.8 years) who underwent complete history and physical examinations and determinations of blood chemistry and anthropometric variables, including AGEs. Serum AGE level was examined by enzyme-linked immunosorbent assay. Vascular [18F]fluorodeoxyglucose (FDG) uptake, an index of vascular inflammation, was measured as blood-normalized standardized uptake value, known as the target-to-background ratio (TBR), by FDG–positron emission tomography (FDG-PET). Furthermore, we examined whether the changes in serum AGE level after treatment with oral hypoglycemia agents (OHAs) were correlated with those of TBR in another 18 subjects whose AGE value was &gt;14.2 units/mL (mean ± 2 SD).

RESULTS
Mean serum AGE level and carotid TBR values were 9.15 ± 2.53 and 1.43 ± 0.22 units/mL, respectively. Multiple stepwise regression analysis revealed that TBR was independently correlated with AGEs (P &lt; 0.001), carotid intima-media thickness (P &lt; 0.01), and BMI (P &lt; 0.02). When age- and sex-adjusted AGE values stratified by TBR tertiles were compared using ANCOVA, a significant trend was observed (P &lt; 0.01). In addition, the changes in AGEs after OHA treatment were positively (r = 0.50, P &lt; 0.05) correlated with those in TBR value.

CONCLUSIONS
The current study reveals that serum AGE level is independently associated with vascular inflammation evaluated by FDG-PET, suggesting that circulating AGE value may be a biomarker that could reflect vascular inflammation within an area of atherosclerosis.
Myeloperoxidase Is an Early Biomarker of Inflammation and Cardiovascular Risk in Prepubertal Obese Children
Authors: Olza Josune , Aguilera Concepcion M. , Gil-Campos Mercedes , Leis Rosaura , Bueno Gloria , Martínez-Jiménez Maria D. , Valle Miguel , Cañete Ramon , Tojo Rafael , Moreno Luis A. , Gil Angel 
Published: August 2012

OBJECTIVE
Obesity is associated with a state of chronic low-grade inflammation. Myeloperoxidase (MPO) plays an important role in the initiation and progression of acute and chronic inflammatory diseases, such as cardiovascular disease (CVD). The objectives of the current study were to evaluate plasma MPO levels in prepubertal obese children and to determine whether MPO could be an early biomarker of inflammation and CVD risk.

RESEARCH DESIGN AND METHODS
In a prospective multicenter case-control study paired by age and sex of 446 Caucasian prepubertal children ages 6–12 years, 223 normal-weight and 223 obese children were recruited. Blood pressure, waist circumference, weight, and height were measured. In addition to MPO, glucose, insulin, metabolic lipid parameters, oxidized low-density lipoproteins, adiponectin, leptin, resistin, C-reactive protein (CRP), interleukin 6, tumor necrosis factor α, matrix metalloproteinase-9 (MMP-9), and plasminogen activator inhibitor 1 were determined.

RESULTS
We found that MPO was elevated in prepubertal obese children and that this enzyme was associated with such proinflammatory and cardiovascular risk biomarkers as CRP, MMP-9, and resistin. Insulin resistance calculated by the homeostatic assessment model was the best predictor of MPO.

CONCLUSIONS
MPO is an early biomarker of inflammation associated with CVD risk in obese children at the prepubertal age.
Obstructive Sleep Apnea in Young Lean Men
Authors: Pamidi Sushmita , Wroblewski Kristen , Broussard Josiane , Day Andrew , Hanlon Erin C. , Abraham Varghese , Tasali Esra 
Published: August 2012

OBJECTIVE
To assess whether the presence of obstructive sleep apnea (OSA) affects glucose metabolism in young, lean individuals who are healthy and free of cardiometabolic disease.

RESEARCH DESIGN AND METHODS
In a prospective design, 52 healthy men (age 18–30 years; BMI 18–25 kg/m2) underwent laboratory polysomnogram followed by a morning oral glucose tolerance test (OGTT). We stratified all subjects according to the presence or absence of ethnicity-based diabetes risk and family history of diabetes. We then used a frequency-matching approach and randomly selected individuals without OSA, yielding a total of 20 control men without OSA and 12 men with OSA. Indices of glucose tolerance, insulin sensitivity, and insulin secretion (early phase and total) were compared between men with OSA and control subjects. The incremental areas under the glucose (incAUCglu) and insulin (incAUCins) curves were calculated using the trapezoidal method from 0 to 120 min during the OGTT.

RESULTS
Men with OSA and control subjects were similar in terms of age, BMI, ethnicity-based diabetes risk, family history of diabetes, and level of exercise. Both groups had normal systolic and diastolic blood pressure and fasting lipid levels. After ingestion of a glucose load, men with OSA had 27% lower insulin sensitivity (estimated by Matsuda index) and 37% higher total insulin secretion (incAUCins) than the control subjects, despite comparable glucose levels (incAUCglu).

CONCLUSIONS
In young, lean, and healthy men who are free of cardiometabolic disease, the presence of OSA is associated with insulin resistance and a compensatory rise in insulin secretion to maintain normal glucose tolerance. Thus, OSA may increase the risk of type 2 diabetes independently of traditional cardiometabolic risk factors.
The stigma of reporting wrongdoing at work: When doing right is perceived as wrong
Authors: Bjørkelo Brita , Macko Maciej 
Published: August 2012

The stigma of reporting wrongdoing at work: When doing right is perceived as wrong
The act of reporting unethical, illegal and illegitimate practices at work, whistleblowing, can be associated with a stigma for the individual in question (Banja, 1985). This article presents the stigmatizing position of reporting wrongdoing at work, types of wrongdoing and individual antecedents. Since empirical studies have shown very few systematic results regarding individual differences, one way to decrease societal stigma can be to relate the act of reporting to other known acts that are perceived upon as more positive within society. We therefore also discuss similarities and differences between the idea of whistleblowing and other concepts such as Organizational Citizenship Behaviour (OCB), in-role, and extra-role behaviour before we make some concluding remarks.
Does work engagement burn out? The person-job fit and levels of burnout and engagement in work
Authors: Chirkowska-Smolak Teresa 
Published: August 2012

Does work engagement burn out? The person-job fit and levels of burnout and engagement in work
This research (N=943) examines the relationship between burnout, work engagement, and organizational factors that play an important role in the strain process (development of burnout), and in the motivational process (work engagement). The aim of the study is to test the relationships of burnout and work engagement, on the one hand, and organizational factors—job demands (workload) and job resources (control, relations with co-workers and superiors, rewards, fairness, and values)—on the other. The results of the analysis call into doubt whether burnout and work engagement are opposite poles of the same dimension, or whether they are independent, though correlated, constructs. Exhaustion and vigour are not the extremes of the same energy dimension, but in the case of cynicism and dedication, the situation is not so clear. It can be said that we are not dealing with the burnout of engagement, but rather with a change in attitude to work (increasing cynicism) on the part of people not suited to their jobs.
Psychological universals and nomothetic aspirations of social psychology
Authors: Dymkowski Maciej 
Published: August 2012

Psychological universals and nomothetic aspirations of social psychology
The experimental social psychology basically rejects idiographism, though its nomothetism is only sometimes similar to the one that dominates in natural traditions. This is illustrated in the paper on instances of the selected theories. They often differ from their equivalents in the natural sciences because they describe the instruments of human psychological functioning which either are non-universal or appear with various frequency in different cultural and/or historical contexts, fulfill diverse functions there, and even sometimes have a different meanings.
Le district krasnostawski sous l'occupation autrchienne dans les années 1915-1918 (partie II)
Authors: Maleszyk Ryszard 
Published: August 2012

Powiat krasnostawski pod okupacją austriacką w latach 1915-1918 (część II)L'article démontre les activités économiques et les investissements des autorités autrichiennes pendant l'occupation sur le terrain du district krasnostawski, ainsi que les problèmes de la vie quotidienne de ses habitants. Dans la partie suivante, l'article décrit les institutions de la justice et les questions liées à l'enseignement sur ce terrain. Il décrit aussi, en abrégé, les activités sociales remarquables des habitants des communes, les parties de district qui ont abouti à une action bien organisée de désarmement des Autrichiens et de prise de pouvoir au début du novembre 1918. Par conséquent, cet article peut compléter les connaissances historiques sur la ville de Krasnystaw et le district krasnostawski au temps de la I
Public battles and private takeovers: Academies and the politics of educational governance
Authors: Wilkins Andrew 
Published: August 2012

Public battles and private takeovers: Academies and the politics of educational governanceIntroduced to the British education system under the Education Act 2002 and later enshrined in the New Labour government White PaperHigher Standards, Better Schools for All(DfES, 2005), the Academies policy was set up to enable designated under-performing schools to ‘opt out’ from the financial and managerial remit of Local Authorities (LAs) and enter into partnerships with outside sponsors. A radical piece of policy legislation, it captured New Labour's commitment to (further) private sector involvement in public sector organisation - what might be termed a neoliberal or advanced liberal approach to education reform. A consequence of this has been the expansion of school-based definitions of ‘public accountability’ to encompass political, business, and other interest groups, together with the enlargement of the language of accountability itself. In this paper I address the importance of rethinking conventional public/private, political/commercial divides in light of these developments and foreground the changing nature of state power in the generation and assembly of different publics.
Eurasian eagle owl (Bubo bubo) colonizing lowland floodplain forests in south Moravia (Czech Republic) and cases of its breeding in wooden nestboxes
Authors: Horal David , ŠKorpíková Vlasta 
Published: August 2012

Eurasian eagle owl (Bubo bubo) colonizing lowland floodplain forests in south Moravia (Czech Republic) and cases of its breeding in wooden nestboxes
This paper presents data on the occurrence and breeding of Eurasian eagle owl (Bubo bubo) in south Moravia, Czech Republic (Břeclav and Znojmo districts), in the floodplains of the Morava and Dyje Rivers, since 1994, and the first cases of confirmed breeding from 2009 to 2011. In two cases, eagle owls bred successfully in large, wooden artificial nestboxes originally installed for saker falcon (Falco cherrug).
Phenological patterns in a natural population of a tropical timber tree species, Milicia excelsa (Moraceae): Evidence of isolation by time and its interaction with feeding strategies of dispersers
Authors: Daïnou Kasso , Laurenty Eric , Mahy Grégory , Hardy Olivier J. , Brostaux Yves , Tagg Nikki , Doucet Jean‐Louis 
Published: August 2012

• Premise of the study: Population genetic structuring over limited timescales is commonly viewed as a consequence of spatial constraints. Indirect approaches have recently revealed reproductive isolation resulting from flowering time (so‐called isolation by time, IBT). Since phenological processes can be subject to selection, the persistence of flowering asynchrony may be due to opposing selective pressures during mating, dispersal, and regeneration phases. Our study aimed to investigate phenology, fruit handling by animals, and their interaction in a timber tree species, Milicia excelsa.• Methods: We analyzed phenological data collected over 6 years on 69 genotyped trees in a Cameroonian natural rainforest complemented by data from germination trials and field observations of dispersers.• Key results: Initiation of flowering was correlated with variation in temperature and relative humidity, but was also affected by genetic factors: pairwise differences in flowering time between nearby individuals correlated with kinship coefficient, and earliness of flowering remained stable over time. A decrease in mean seed production per fruit with increasing flowering time suggests selection against late bloomers. However, germination rate was not affected by seed collection date, and the main seed disperser, the bat Eidolon helvum, seemed to increase in abundance at the end of the reproductive season and preferred trees in open habitats where early and late bloomers are expected.• Conclusions: The pairwise approach performs well in detecting IBT. The persistence of different mating pools in such a case may result from a trade off between selective forces during the mating and seed dispersal processes.
Le polar africain
Authors: Ferreira-Meyers Karen 
Published: August 2012

Le polar africain est un phénomène nouveau. Il se divise en deux catégories : d’une part, les romans qui font une représentation de la réalité et, d’autre part, ceux qui reproduisent les aspirations du continent. Selon la critique littéraire, la littérature africaine est un miroir à travers lequel se reflète la vie en Afrique dans ses différentes composantes et sa diversité. Il ne s’agit pas uniquement de dire, mais de dire vrai, de situer dans le registre du vraisemblable une thématique qui relève de l’abject. Dans ce jeu des représentations, le roman policier affiche sa singularité au détriment des autres genres, notamment à travers un intertexte explicite avec divers discours sociaux. Le présent article trace l’historique de l’apparition et de la divulgation du roman policier africain de langue européenne, francophone, anglophone et lusophone, afin de pouvoir analyser la production contemporaine.
Modular Abelian Varieties Over Number Fields
Authors: Guitart Xavier , Quer Jordi 
Published: August 2012

AbstractThe main result of this paper is a characterization of the abelian varieties B/K defined over Galois number fields with the property that the L-function L(B/K; s) is a product of L-functions of non-CM newforms over ℚ for congruence subgroups of the form Γ1(N). The characterization involves the structure of End(B), isogenies between the Galois conjugates of B, and a Galois cohomology class attached to B/K.We call the varieties having this property strongly modular. The last section is devoted to the study of a family of abelian surfaces with quaternionic multiplication. As an illustration of the ways in which the general results of the paper can be applied, we prove the strong modularity of some particular abelian surfaces belonging to that family, and we show how to find nontrivial examples of strongly modular varieties by twisting.
IMPACTO DE LA PREPARACIÓN DEL SUELO SOBRE LAS CARACTERISTICAS FISICAS DEL SUELO, CALIDAD Y RENDIMIENTO DE LAS RAICES DE YUCA (Manihot Crantz), VARIEDAD ALGODÓN, NUEVA GUINEA - RAAS
Authors: Duarte-Centeno Nubia , Figueroa-Martínez Manuel , Hernández Luis , Aguilar-Bustamante Víctor 
Published: August 2012

El estudio se realizó en el Centro de Desarrollo Tecnológico (CDT) del Instituto Nicaragüense de Tecnología Agropecuaria (INTA) en Nueva Guinea, RAAS desde Octubre de 2005 a Agosto de 2006. El objetivo general fue evaluar cuatro sistemas de labranza sobre las propiedades físicas del suelo, el crecimiento y rendimiento del cultivo de la yuca variedad Algodón, así como la calidad de las raíces. Los tratamientos estudiados fueron: subsoleo más encamado (SE), grada más encamado (GE), cero labranza (CL) y tracción animal (TA). El diseño utilizado fue un arreglo de bloques completos al azar (BCA) con tres repeticiones. Las variables de suelo evaluadas fueron: densidad aparente, densidad real, porosidad total y capacidad de campo. Las variables agronómicas estudiadas fueron altura de planta, diámetro del tallo, peso fresco de la planta, número de raíces totales por planta, número de raíces exportables, longitud de raíces exportables, diámetro de raíces exportables, peso de raíces exportables, rendimiento de raíces exportables, rendimiento de raíces no exportables y rendimiento total de raíces. Para el análisis de los datos se usó el paquete estadístico SAS Institute V 8 a base de Análisis de Varianza (ANDEVA) y comparación de rangos múltiples de medias por TUKEY al 5% de margen de error. El suelo preparado con tracción animal (TA), presentó los menores valores de densidad aparente y mayor porcentaje de porosidad del suelo. Las plantas de yuca alcanzaron la mayor altura, el mayor diámetro y mayor peso fresco con cero labranza (CL) y tracción animal (TA). El mayor número de raíces totales por planta fue alcanzado con tracción animal (TA) seguido de cero labranza (CL). El mayor número de raíces exportables, el mayor diámetro de raíces exportables y peso de las raíces exportables fue alcanzado con el método cero labranza (CL) seguido de tracción animal (TA). El mayor rendimiento de raíces totales fue alcanzado en el suelo con Cero labranza (CL), así como el mayor rendimiento de raíces exportables y no exportables con una relación de 76% de raíces exportables DOI: http://dx.doi.org/10.5377/calera.v11i17.774 La Calera Vol.11 No.17, p.26-32
GERMOPLASMA DE TOMATE SILVESTRE (Lycopersicum spp.) EN LA RESERVA DE RECURSO GENÉTICOS DE APACUNCA (RRGA), CHINANDEGA
Authors: González Benavides Alvaro , Cisne José Contreras , Querol Daniel Lipcovich , Centeno Juan Carlos Morán 
Published: August 2012

Considerando la importancia del tomate como cultivo hortícola, el presente estudio se realizó con el fin de aportar información in situ y ex situ usando seis muestras de poblaciones d tomate silvestre (Lycopersicum spp.), endémicas de la Reserva de Recursos Genéticos de Apacunca (RRGA). Se implementaron normas de riego (0.4, 0.7 y 1.1 litros/planta/día) y niveles de biofertilizante (0, 100, 200 y 300 cc por bombada de 20 litros). Los experimentos establecidos ex situ fueron arreglados en diseños en franjas con tres réplicas y se utilizaron análisis univariados y multivariados en datos morfológicos. Los estudios in situ y ex situ indican que las poblaciones difieren en algunas variables, en donde variables de frutos y de planta fueron afectadas de manera significativa por las normas de riego y los niveles de biofertilizante, respectivamente. La mayor cantidad de frutos se obtuvieron con la dosis intermedia de riego, y los mayores niveles de biofertilizante. Los primeros tres componentes principales aislaron el 73.2 % de la variación total, y las dimensiones del fruto, longitud de tallo y entrenudos en la planta fueron las variables discriminantes entre los tratamiento conformados. Las poblaciones evaluadas in situ, con normas de riego y niveles de biofertilizante conformaron tres núcleos bien diferenciados. Las mediciones realizadas en las poblaciones en su hábitat natural (in situ) fueron menos variantes, en comparación con las poblaciones ex situ y expuestas a tratamientos. Las características encontradas en el tomate silvestre de la Reserva, sugieren que puede ser utilizado en la alimentación de las familias rurales, por lo tanto, se debe asegurar su conservación in situ y ex situ. DOI: http://dx.doi.org/10.5377/calera.v11i17.775 La Calera Vol.11 No.17, p.33-40
ARBOLES DE SOMBRA E INTENSIDAD DEL CULTIVO AFECTAN EL RENDIMIENTO DE CAFÉ (Coffea arabica L.) Y LA VALORACIÓN ECOLÓGICA EN MASATEPE, NICARAGUA
Authors: Moraga Pedro Quezada , Bolaños Ilich Roger Taleno , Pilz Mario , Munguía Rodolfo Hernández , Jürgen Alfred Hermann Pohlan , Barios Mirna , Haggar Jeremy , Gamboa William Moya 
Published: August 2012

En el año 2000 se establecieron dos repeticiones de un ensayo de café, en el Centro de Capacitación y Servicios Regionales del Café del Pacífico Sur – UNICAFE; una tercera repetición fue establecida en el año 2001 en el Centro Experimental Campos Azules (CECA) del INTA, en el Municipio de Masatepe, departamento de Masaya, Nicaragua. El propósito general del ensayo fue evaluar la influencia de diferentes tipos de sombra: Simaruba glauca + Tabebuia rosea (SGTR), Simaruba glauca + Inga laurina (SGIL), Samanea Saman + Tabebuia Rosea (SSTR), Inga laurina + Samanea saman (ILSG) y un cafetal a Pleno sol (PS), con dos niveles de insumo Convencional intensivo (CI) y Convencional moderado (CM), sobre la producción y rendimiento de café oro y la valoraron de los servicios ambientales como Biodiversidad, Captura de carbono, Conservación de suelo y de agua. Además, se incluyeron los tratamientos orgánico intensivo (OI) y Orgánico moderado (OM). Se determinó que la sombra afectó la producción de café oro, pero mejoró el rendimiento en comparación al cultivo a pleno sol. La combinación de sombra de SGTR interactuando con las aplicaciones de insumos orgánicos intensivos, registró mejor producción promedio (2674 kg oro ha-1) de la cosecha 5, superando al tratamiento a pleno sol con uso de insumos convencionales intensivo. Cafetales bajo especies arbóreas y nivel de sombra adecuada con un manejo orgánico intensivo pueden llegar a la misma producción que el cultivo a pleno sol con un tratamiento intensivo convencional. Adicional a esto, los sistemas con sombra mejoran la calidad y las condiciones ecológicas, también agregan valor por la madera, leña y frutos producidos y/o el pago por los servicios ambientales. El tratamiento SGTR brindó las mejores condiciones de hábitat y conservación de suelo, sin embargo, respecto a la fijación de carbono la combinación SSIL fue superior (24.41 SGTR vs 92.64 SSIL). Futuras investigaciones deberán evaluar más detalles sobre el efecto, uso y valor ecológico de especies de sombra y su influencia particular en la calidad en taza a diversas altitudes. DOI: http://dx.doi.org/10.5377/calera.v11i17.776 La Calera Vol.11 No.17, p.41-47