bluuebunny/crossref_metadata_2025_split huggingface dataset:
Folic Acid Effect on Arginase Activity in Human Colostrum and Mature Milk
Authors: Bjelakovic Ljiljana , Kocic Gordana , Stojanovic Ivana , Jevtovic-Stoimenov Tatjana , Najman Stevo , Sokolovic Dusan , Stojanovic Svetlana , Kocic Gordana 
Published: August 2013

Abstract
Folic acid, or folates are available from a large variety of sources, such as green leafy vegetables (spinach, beans) and liver. The importance of folates is based on their requirement as coenzymes in the transfer and utilization of one-carbon units in a variety of biosynthetic reactions. Folate is an essential cofactor for the de novo biosynthesis of purine nucleotides and thymine, thus influencing RNA and DNA synthesis. Therefore, during periods of rapid cell regeneration and growth, such as pregnancy and infancy, increased amounts of folate are required.
Folate has the roles in the prevention of neural tube defects, an important cause of infant mortality and disability. The periconceptional folic acid intake reduces the risk of neural tube defects.
Arginase, as part of the urea cycle, detoxifies human body from ammonia. Its activity is important in the production of ornithine, subsequently leading to the production of polyamines (spermine and spermidine), glutamate or proline, and nitric oxide. Arginase is normally present in mother's milk.
In the present study, the effect of folic acid supplementation during pregnancy on the dynamics of arginase activity and malondialdehyde concentration in human colostrum and mature milk was studied.
The obtained results suggest that in breastfeeding mothers' colostrum and mature human milk samples, supplemented with folic acid during pregnancy (400mg/daily periconceptionaly), the arginase activity increases compared with the enzyme activity in milk samples taken from mothers who did not take folic acid. At the same time, the supplementation with folic acid causes malondialdehyde decrease in colostrum and mature milk.
Influence of Retinopathy on Plasma Concentrations of total Homocysteine and other Biochemical Parameters in Algerian Patients with Type 2 Diabetes Mellitus
Authors: Amrane Mounira , Houcher Zahira , Begag Samia , Houcher Bakhouche , Benlatreche Cherifa , Touabti Abderrezak , Laouamri Slimane , Malek Rachid 
Published: August 2013

Abstract
Homocysteine (HCY) has been identified as a risk factor for vascular disease in the general population. Diabetic retinopathy (DR) itself rather than hyperhomocysteinemia is the leading cause of blindness among patients with type 2 diabetes mellitus (T2DM). Our study was conducted with 60 healthy control subjects and 178 subjects with T2DM. They were enrolled in the Diabetes Prevention Program from September 2007 to December 2008. Of the 178 patients, 121 cases (68%) had DR Mean plasma total HCY (tHCY) levels were found to be higher in T2DM patients compared to controls (p <0.001), and were also higher than that of the DR group (p <0.001). Plasma folic acid levels were lower in the DR group compared with T2DM without DR and the control group (p <0.001), but there were no significant differences between the latter and the controls. Moderate hyperhomocysteinemia was significantly associated with lower vitamin B12 and folic acid concentrations and older age. Concentrations of serum total cholesterol, LDL-cholesterol (LDL-C), and triglycerides (TG) were significantly raised (p <0.001) whereas the level of HDL-cholesterol (HDL-C) was decreased (p <0.001) in diabetic subjects as compared to controls. Logistic regression analysis showed that DR after adjustment was significantly associated with the following factors: cholesterol, HDL-C and TG. The analysis in DR patients after controlling for cholesterol and TG was independent of plasma tHCY concentrations (OR = 28.5 and OR = 11.9; respectively). In conclusion, results suggest a possible association between moderate hyperhomocysteinemia, traditional risk factors and folic acid deficiency could be an independent risk factor for DR.
Microstructures and surface performance of laser melting deposited composites on a Ti alloy
Authors: Li Peng 
Published: August 2013

AbstractThis work is based on the dry sliding wear and cyclic oxidation of composites deposited on a TA1 substrate using laser melting deposition (LMD) technique, the parameters of which are such as to provide almost crack-free composites with minimum dilution and very low porosity. To our knowledge, it is the first time that Stellite SF12-Al-FeSi-B4C mixed powders are deposited as hard composites by LMD technique. Scanning electron microscopy results indicate that such composites with metallurgical joint to a TA1 substrate were formed. It is noted that many nanocrystalline/amorphous phases are also produced, which improve the surface performance of such composites. Compared with the TA1 substrate, improvement of cyclic oxidation and wear resistance are obtained for such composites.
Time variation in an optimal asymmetric preference monetary policy model
Authors: Cassou Steven P. , Vázquez Jesús 
Published: August 2013

AbstractThis paper considers a time varying parameter extension of the Ruge-Murcia’s (Ruge-Murcia, F. J. 2003. “Does the Barro-Gordon Model Explain the Behavior of us Inflation? A Reexamination of the Empirical Evidence.”
The Role of Resin Cement on Bond Strength of Glass-fiber Posts Luted Into Root Canals: A Systematic Review and Meta-analysis of In Vitro Studies
Authors: Sarkis-Onofre R , Skupien JA , Cenci MS , Moraes RR , Pereira-Cenci T 
Published: August 2013

SUMMARY
Because there are several ways to cement glass-fiber posts (GFPs) into root canals, there is no consensus on the best strategy to achieve high bond strengths. A systematic review was conducted to determine if there is difference in bond strength to dentin between regular and self-adhesive resin cements and to verify the influence of several variables on the retention of GFPs. This report followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. In vitro studies that investigated the bond strength of GFPs luted with self-adhesive and regular resin cements were selected. Searches were carried out in the PubMed and Scopus databases. No publication year or language limit was used, and the last search was done in October 2012. A global comparison was performed between self-adhesive and regular resin cements. Two subgroup analyses were performed: 1) Self-adhesive × Regular resin cement + Etch-and-rinse adhesive and 2) Self-adhesive × Regular resin cement + Self-etch adhesive. The analyses were carried out using fixed-effect and random-effects models. The results showed heterogeneity in all comparisons, and higher bond strength to dentin was identified for self-adhesive cements. Although the articles included in this meta-analysis showed high heterogeneity and high risk of bias, the in vitro literature seems to suggest that use of self-adhesive resin cement could improve the retention of GFPs into root canals.
The Effect of TMPTMA Addition on Electron-beam Irradiated LDPE, EVA and Blend Properties
Authors: Sabet M. , Savory R. M. , Hassan A. , Ratnam C. T. 
Published: August 2013

Abstract
In this work low density polyethylene (LDPE) and ethylene vinyl acetate (EVA) were blended in the presence of trimethylol propane trimethylacrylate (TMPTMA) (0 to 6 phr). The resultant blends were irradiated with a 3 MeV electron-beam resulting in dosages of 0 to 240 kGy using a rhodotron accelerator system. The effect of radiation exposure on the LDPE/EVA/TMPTMA blend properties were investigated with respect to gel content, tensile strength and elongation up to breakage of the blends. The findings indicate that increasing EVA and TMPTMA content yield tighter network structures through enhanced blend crosslinking, which is a direct consequence of irradiation. For pure EVA significant tensile strength improvements are evident as irradiation increases up to 210 kGy. Irradiated blends exhibit improved tensile strength and elongation at breakage with respect to pure LDPE and EVA. Volume resistivity (VR) and dielectric constant (DC) of the blends were also studied as a function of EVA content, TMPTMA content and radiation dosage. Increasing EVA and TMPTMA content enhances DC and VR values, whereas, increasing irradiation dosage only effects VR values of the blends. The maximum VR value attained in this work corresponds to a radiation dosage of 170 kGy and a blend comprising of 30 wt% of EVA.
Flammability and Thermal Characterization of Aluminum Hydroxide Filled with LDPE
Authors: Sabet M. , Hassan A. , Ratnam C. T. 
Published: August 2013

Abstract
Aluminum hydroxide (ATH), a non-toxic and environmentally friendly flame retardant, was characterized using thermogravimetric analysis (TGA) and differential thermal analysis (DTA). The effect of ATH content on flammability properties of LDPE was also determined using limiting oxygen index (LOI) and smoke density test. The thermal characterization studies showed that the effective temperature range for ATH as a flame retardant is 200 to 350°C. In water release test, it was determined that the release of the water by ATH degradation in ATH increased with increasing temperature. The LOI test showed that the flame retardancy of LDPE increased with increasing ATH content and decreasing ATH particle size. The smoke density test proved that addition of ATH reduced effectively the smoke density of a burning LDPE. It was studied in this paper the effect of ATH particle size on thermal, flammability and viscosity of ATH filled with LDPE.
Paranoid Ideation and Assessments of Trust
Authors: Kirk Hannah , Gilmour Andrea , Dudley Robert , Riby Deborah M 
Published: August 2013

The ability to make accurate social judgements is crucial to effective functioning in society. Individuals suffering from paranoia are suspicious and mistrustful of others and consequently may have difficulties accurately assessing information about others within their environment. We investigated the effects of paranoid ideation on evaluations of trustworthiness from unfamiliar faces in a non-clinical sample. Measures of paranoid beliefs about others were used to assess 122 typically developing young adults. Individuals categorised with high paranoid ideation (n = 25) and low paranoid ideation (n = 23) subsequently rated unfamiliar faces that had previously been manipulated to look untrustworthy, of average trust, and trustworthy. Individuals high in paranoid ideation rated faces as significantly less trustworthy than those low in paranoid ideation. Both groups altered their ratings according to the trustworthiness of the face, but those high in paranoia rated all faces as less trustworthy. The findings suggest a bias in social judgements in individuals with high levels of paranoid ideation. They are able to judge faces for trustworthiness but have a bias towards a lower estimation of trust.
HE4 can Help Discriminate Women with Malignant Ovarian Tumors only if CA125 Levels are Elevated
Authors: Pitta Denise da Rocha , Sarian Luis Otávio , Aparecida Campos Elisabete , Andrade Liliana Lucci De Angelo , Sallum Luis Felipe , Bragança Joana Froes , Campos Camila de Mello , Derchain Sophie 
Published: August 2013

Objective To evaluate the performance of mesothelin, CA125, HE4 and ROMA index in the detection of malignant ovarian tumors. Study Design This is a cross-sectional study including 199 women with adnexal masses (67 with malignant tumors and 132 with benign tumors) and 150 healthy women (controls). We used a recursive multivariate partitioning algorithm to assess the contribution of each of the serum markers and the ROMA index to the discrimination of women with malignant tumors. Also, the areas under the ROC curves (AUC) for each of the serum markers and for the ROMA index were compared using the Venkatraman's projection-permutation test. Results In the recursive model, CA125 had the best performance in discriminating women with malignant tumors. In women with normal-range CA125 levels, none of the other markers contributed to the discrimination of women with malignant tumors. In women with elevated CA125 levels, elevated HE4 levels were associated with an increased risk of harboring a malignant tumor. The AUC for mesothelin was smaller than that for all the other curves, and both the ROMA index and CA125 had better AUC than HE4. Conclusion In women with normal CA125 levels, neither mesothelin nor HE4 contributed to discriminate women with malignant ovarian tumors; however, for women with elevated CA125 levels HE4 may help discriminating those who have a malignant ovarian tumor.
Le choix d’une vie sans enfant à travers le prisme des normes parentales et conjugales
Authors: Debest Charlotte 
Published: August 2013

Avec la généralisation de la contraception (principalement féminine) durant la seconde moitié du xxe siècle dans la majorité des pays occidentaux et les avancées scientifiques en matière de procréation médicalement assistée, le concept de famille s’élargit et la dissociation entre conjugalité et parentalité est posée comme une évidence. Or, nous nous interrogerons, dans cet article, au travers d’entretiens sociologiques effectués avec des personnes volontairement sans enfant, sur l’évidence de cette dissociation/conciliation entre vie conjugale et vie parentale. En effet, les personnes volontairement sans enfant mettent en lumière les contradictions entre les conditions normatives du « métier » de parent et celles du « métier » de partenaire amoureux et sexuel.
Video capture on student-owned mobile devices to facilitate psychomotor skills acquisition: A feasibility study
Authors: Hinck Glori , Bergmann Thomas F. 
Published: August 2013

ObjectiveWe evaluated the feasibility of using mobile device technology to allow students to record their own psychomotor skills so that these recordings can be used for self-reflection and formative evaluation.MethodsStudents were given the choice of using DVD recorders, zip drive video capture equipment, or their personal mobile phone, device, or digital camera to record specific psychomotor skills. During the last week of the term, they were asked to complete a 9-question survey regarding their recording experience, including details of mobile phone ownership, technology preferences, technical difficulties, and satisfaction with the recording experience and video critique process.ResultsOf those completing the survey, 83% currently owned a mobile phone with video capability. Of the mobile phone owners 62% reported having email capability on their phone and that they could transfer their video recording successfully to their computer, making it available for upload to the learning management system. Viewing the video recording of the psychomotor skill was valuable to 88% of respondents.ConclusionsOur results suggest that mobile phones are a viable technology to use for the video capture and critique of psychomotor skills, as most students own this technology and their satisfaction with this method is high.
ortho‐(Dimesitylboryl)phenylphosphines: Positive Boryl Effect in the Palladium‐Catalyzed Suzuki–Miyaura Coupling of 2‐Chloropyridines
Authors: Malacea Raluca , Chahdoura Faouzi , Devillard Marc , Saffon Nathalie , Gómez Montserrat , Bourissou Didier 
Published: August 2013

AbstractCatalytic systems combining ortho‐(dimesitylboryl)phenylphosphines and palladium precursors have been evaluated in the Suzuki–Miyaura couplings of chloro‐N‐heterocycles, in particular 2‐chloropyridines, with arylboronic acids. The Lewis basic character of the substrates does not interfere with the Lewis acidic site of the ligands, even for a substrate featuring free NH2 groups. The influence of several reaction parameters has been studied and the ortho‐dimesitylboryl moiety was actually found to substantially enhance the catalytic performance. The role of this group has been examined using preformed phosphine‐borane/Pd complexes and the formation of an original phosphine/η4‐boratabutadiene complex has been identified as a possible deactivation pathway. Regioselective coupling of 2,6‐dichloro‐3‐nitropyridine with phosphine‐borane/Pd catalysts has also been explored, and sequential double cross‐couplings were found to give a direct and efficient access to unsymmetrical 2,6‐diarylpyridines.magnified image
Development of a Continuously Operating Process for the Enantioselective Synthesis of a β‐Amino Acid Ester via a Solvent‐Free Chemoenzymatic Reaction Sequence
Authors: Strompen Simon , Weiß Markus , Gröger Harald , Hilterhaus Lutz , Liese Andreas 
Published: August 2013

AbstractA sequential, chemoenzymatic process for a continuously operating production of the chiral β‐amino acid ester ethyl (S)‐3‐(benzylamino)butanoate was developed. The reactor set‐up combined a plug‐flow reactor for the thermal aza‐Michael addition of benzylamine to trans‐ethyl crotonate coupled to a subsequent packed‐bed reactor for the lipase (Novozym 435)‐catalyzed kinetic resolution of the racemic intermediate product, which was formed in the initial step. The coupled reactors were operated continuously for a time period of 4 days without significant loss of enzyme activity. The target β‐amino acid ester was obtained with 92% conversion in the plug‐flow reactor and 59% conversion in the packed bed reactor at high enantiomeric excess of >98%. A space‐time yield of 0.4 kg L−1 d−1 was calculated for the total reactor system and 1.8 kg L−1 d−1 based solely on the volume of the packed bed reactor. A total turnover number of 158,000 was calculated for the biocatalyst assuming the same deactivation rate as observed in batch experiments. The continuously operating, solvent‐free process thus represents an efficient method for the enantioselective production of a value added (S)‐β‐amino acid ester starting from cheap substrates.Abbreviations: CALB=Candida antarctica lipase B; CSTR=continuously stirred tank reactor; di=inner diameter [mm]; ee=enantiomeric excess; ε=porosity; kcat,obs=apparent turnover number [h−1]; kdeact=enzyme deactivation constant [h−1]; L=length of reactor [m]; m̄p=average mass of a single particle [g]; N435=Novozym 435 (Candida antarctica lipase B immobilized on acrylic resin); PBR=packed‐bed reactor; PFR=plug‐flow reactor; PTFE=polytetrafluoroethylene; ρbp=bulk particle density [kg m−3]; ρp=density of carrier material [kg m−3]; Q=productivity [kg ${{\rm kg}{{- 1\hfill \atop {\rm N435}\hfill}}}$ d−1]; R=channel radius of curvature [cm]; ttn=total turnover number [mol mol−1]; T=temperature [°C]; τ=residence time [h]; uf=fluid velocity [cm min−1]; $\dot \nu $=volumetric flow rate [mL min−1]; νι=flow rate of substance [mmol min−1]; V=volume [mL]; χi=mole fraction of compound i; Xi=conversion of compound i; STY=space‐time yield [kg L−1 d−1].magnified image
Potassium (E)‐Alkenylaryltrifluoroborates: Orthogonal Functionalization of Haloaryltrifluoroborates via Heck–Mizoroki Reaction
Authors: Song Jung Ho , Kim Taejung , Lee Jae Wook , Moon Soo‐Yeon , Kim Won‐Suk , Ham Jungyeob 
Published: August 2013

AbstractA series of di‐ or trisubstituted alkene‐containing potassium organotrifluoroborates was prepared from the corresponding haloaryltrifluoroborates via palladium‐catalyzed Heck–Mizoroki reaction with various olefins in good to excellent yields. Furthermore, the Suzuki–Miyaura cross‐coupling reaction of these alkenylaryltrifluoroborates was successfully carried out with aryl and alkenyl bromides using 5 mol% of tetrakis(triphenylphosphine)palladium(0) and 3.0 equiv. of cesium carbonate in aqueous 1,4‐dioxane under microwave irradiation.magnified image
Generation of a Low‐Valent Titanium Species from Titanatrane and its Catalytic Reactions: Radical Ring Opening of Oxetanes
Authors: Takekoshi Naoto , Miyashita Kenji , Shoji Noriaki , Okamoto Sentaro 
Published: August 2013

AbstractTreatment of a titanatrane complex with trimethylsilyl chloride and magnesium powder in tetrahydrofuran generated a low‐valent titanium species. This species catalyzed the radical ring opening of epoxides and oxetanes to produce the corresponding less substituted alcohols. The reagent also catalyzed the deallylation and depropargylation of allylic and propargylic ethers, respectively, to provide the parent alcohols.magnified image
Atropodiastereoselective CH Olefination of Biphenyl p‐Tolyl Sulfoxides with Acrylates
Authors: Wesch Thomas , Leroux Frédéric R. , Colobert Françoise 
Published: August 2013

AbstractA stereoselective method for the synthesis of axially chiral biaryl scaffolds by CH bond functionalization was accomplished using chiral sulfoxide both as the directing group enabling the regioselective activation of a CH bond and as the chiral auxiliary generating an asymmetric environment in the coordination sphere of the metal complex. We have demonstrated the directing ability of the p‐tolylsulfinyl group in promoting the Pd(II)‐catalyzed CH olefination of biphenyls.magnified image
Effects of maya ancestry and environmental variables on knee height and body proportionality in growing individuals in merida, yucatan
Authors: Vázquez‐Vázquez Adriana , Azcorra Hugo , Falfán Ina , Argáeź Jorge , Kantun Diódora , Dickinson Federico 
Published: August 2013

ABSTRACTObjectiveIdentify the biological, social, and economic conditions influencing the knee height/stature index (KHSI) in growing individuals of Maya ancestry in the city of Merida, Yucatan, Mexico.MethodsThe hypothesis was that KHSI values would be lower in subjects with two Maya surnames. This was tested by analyzing the effect of a series of environmental, biological, and socioeconomic variables on stature and knee height (KH). Data were collected from 2008 to 2009 from 841 individuals (444 girls), 9 to 17 years of age, in Merida, Yucatan, Mexico. Ancestry was used as a proxy for genetics, and based on number of Maya surnames (2, 1, or none). The KHSI was calculated for all individuals. Multiple regression models were run to identify the variables that best explained variation in stature, KH, and KHSI.ResultsAncestry negatively (P < 0.05) affected stature, but birth weight, crowding index, and mother's education level (MEL) were more significant (P < 0.01). Ancestry had no effect on KH and KHSI values, but birth weight and MEL had a significant effect. Individuals who had grown up in an adverse environment, in terms of MEL, had higher KHSI values. Apparently, lower leg length was proportionally longer than thigh length in the sample.ConclusionsGrowth measurements were more responsive to the studied environmental variables than to ancestry‐related genetic conditions. Genetic predisposition is, therefore, not the primary cause of short stature in this sample of Yucatec Mayas. Am. J. Hum. Biol., 25:586‐593, 2013. © 2013 Wiley Periodicals, Inc.
Nicotinische Acetylcholinrezeptor‐Agonisten: ein Meilenstein für den modernen Pflanzenschutz
Authors: Jeschke Peter , Nauen Ralf , Beck Michael Edmund 
Published: August 2013

AbstractDie Schädigung von Nutzpflanzen durch wirbellose Schädlinge ist eine große Bedrohung vor dem Hintergrund des kontinuierlich steigenden Nahrungsbedarfs einer wachsenden Weltbevölkerung. Daher sind effiziente Pflanzenschutzmaßnahmen in der breiten Vielfalt der landwirtschaftlichen Produktion von größter Bedeutung für nachhaltige Erträge. Die Entdeckung synthetischer Agonisten, die selektiv an nicotinischen Acetylcholin‐Rezeptoren (nAChR) im Zentralnervensystem von Schadinsekten wirken und als Insektizide Verwendung finden, war ein Meilenstein in der angewandten Pflanzenschutzforschung. Diese Verbindungen läuten wegen ihrer hohen Spezifität am aktiven Zentrum und Vielseitigkeit in der Anwendung eine neue Ära der Bekämpfung einiger der weltweit schwerwiegendsten Schadinsekten ein. Diese Insektizide haben nicht nur Bedeutung als Insektenbekämpfungsmittel in der Landwirtschaft, sie haben auch unsere Kenntnisse über die Biochemie der nicotinischen Acetylcholin‐Rezeptoren von Insekten enorm erweitert. Der globale wirtschaftliche Erfolg der synthetischen nAChR‐Agonisten als Insektizide macht den nicotinischen Acetylcholin‐Rezeptor immer noch zu einem der vielversprechendsten Ziele für die Insektizidforschung.