bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pemberdayaan Karang Taruna dalam Mendukung Gerakan 3M Selama Pandemi Covid-19
Authors: Zaini Mad , Supriyadi Supriyadi , Pratama Koernia Nanda 
Published: August 2024

Sasaran program pengabdian masyarakat ini adalah kelompok karang taruna di Kelurahan Kranjingan, Kabupaten Jember. Tujuan dari program ini adalah menambah pemahaman mengenai virus covid-19 serta upaya untuk meningkatkan peran aktif dari karang taruna. Permasalahan yang dihadapi oleh mitra adalah 1) rendahnya peran serta anggota karang taruna dalam pencegahan covid-19, 2) kurangnya kepatuhan masyarakat dalam menjalankan protokol kesehatan, 3) belum ada informasi yang diberikan kepada karang taruna dalam pencegahan covid-19. Target dan luaran yang dihasilkan adalah 1) produk jasa berupa pengetahuan dan ketrampilan pencegahan covid-19, 2) tersedia buku sederhana pencegahan covid-19, 3) demonstrasi 3M. Metode yang digunakan untuk mencapai tujuan tersebut adalah 1) sosialisasi, 2) pendampingan, 3) demonstrasi gerakan 3M. Hasil dari kegiatan sosialisasi kepada mitra adalah kesepakatan untuk dilakukan penyuluhan dan praktik gerakan 3M pada karang taruna. Kegiatan pengbdian masyarakat ini diikuti oleh 20 karang taruna, dilakukan dengan memberikan pengetahuan dan ketrampilan tentang gerakan 3M kepada karang taruna sebagai upaya bersama dalam membantu masyarakat dalam menanggulangi penyebaran covid-19 khususnya di Kelurahan Kranjingan Kabupaten Jember.
Edukasi PHBS melalui Pemberdayaan Santri di Pondok Pesantren Modern Daarul Abror Bangka
Authors: Chaerani Erni , Widyaastuti Eny Erlinda , Djuria Syafrina Arba'ani 
Published: August 2024

Pembangunan kesehatan merupakan upaya yang dilaksanakan dengan tujuan untuk meningkatkan kesadaran, kemauan, dan kemampuan hidup sehat bagi setiap orang termasuk santri pondok pesantren agar terwujud derajat kesehatan yang setinggi tingginya. Perilaku hidup bersih dan sehat (PHBS) merupakan salah satu cara mencapai derajat kesehatan yang baik. Pondok Pesantren Modern Daarul Abror merupakan pesantren di Bangka Belitung yang terletak di Kecamatan Mendo Barat Kabupaten Bangka. Pengasuh dan pengurus pesantren telah berupaya menyediakan sarana dan memberikan pengetahuan pentingnya PHBS, tetapi para santri masih mengalami kesulitan dalam mengimplemetasikan nilai-nilai kesehatan karena kurangnya pengetahuan tentang dasar-dasar kesehatan dan PHBS sehingga kesadaran akan berperilaku hidup bersih dan sehat belum optimal. Edukasi PHBS dengan memberdayakan santri sebagai kader kesehatan merupakan kegiatan pengabdian kepada masyarakat (PkM) yang berupaya membelajarkan santri menjadi pemimpin dan role model dalam berperilaku hidup bersih dan sehat. Metode yang digunakan dalam PkM adalah metode partisipatoris. Metode dimaksud tim pengabdi turun langsung melakukan edukasi PHBS kepada kader kesehatan santri dalam bentuk pelatihan. Santri yang dilatih menjadi kader berjumlah 27 orang. Pengetahuan kader santri meningkat setelah diberi pelatihan, rata-rata nilai pre test 74.63 dan post test 83.33. Santri mendapat pengalaman menjadi fasilitator dalam memonitor pelaksanaan PHBS di pesantren. Solusi permasalahan PHBS di Pondok Pesantren Daarul Abror tidak lepas dari peran pimpinan dan pembina santri. Keberhasilan santri menjadi kader kesehatan karena dukungan pembina pesantren yang kooperatif mendampingi santri dalam menjalankan perannya sebagai kader kesehatan. Memberdayakan santri menjadi kader kesehatan dapat mempercepat tercipta pesantren yang sehat.
PENGARUH KUALITAS PRODUK, HARGA DAN PROMOSI TERHADAP KEPUTUSAN PEMBELIAN PRODUK GARNIER (Studi Kasus Pada Konsumen yang ada di Kota Malang)
Authors: Mersi Vilomena , Rusno Rusno , Suharso Arien Anjar Puspitosari 
Published: August 2024

Peneliti ini bertujuan agar memahami i peranan kualitas produk, Harga dan Promosi pada keputusan pembelian prodak Garnier di Kota Malang, Metode yang digunakan adalah accidental sampling. Jenis riset ekspalanatory research dengan sumber data primer. Riset ini memakai kuantitatif, teknik pengumpulan data yang dipakai ialah angket. Populasi pada riset ini yaitu konsumen Garnier di Kota Malang dengan jumlah sampel 160 reponden. Teknik analisis data dalam riset ini yaitu memakai regresi linear berganda. Temuan riset menunjukan secara bersama-sama kualitas produk, harga dan promosi berpengaruh signifikan terhadap keputusan pembelian produk Garnier oleh konsumen di Kota Malang. Kualitas produk, harga dan promosi berdampak positif serta signifikan terhadap keputusan pembelian produk Garnier oleh konsumen di Kota Malang.
Composition and variation of stable carbon and nitrogen isotope in south-western Tibetan Plateau
Authors: Qu Songbo , Xu-Ri Xu-Ri , Yu Jiaoneng , Shama Ribu , Lei Haojing , Tian-Liang Tian-Liang , Bayarsaikhan Sainbuyan , Jukov Azzaya , Tsendeekhuu Munkhbat , Borjigidai Almaz 
Published: August 2024

Abstract

Ecosystem stable isotopic values of carbon and nitrogen (δ13C and δ15N) can offer valuable insight into terrestrial ecosystem. However, the factors influencing δ13C and δ15N in alpine grasslands are not clear enough. To address this gap, we measured δ13C and δ15N for soil and Astragalus plants along an altitudinal gradient (3500 — 5000 m) in the south-western Tibetan Plateau, which was unreported by previous studies. As an ecological indicator reflecting nitrogen (N) cycling, soil δ15N values are higher than the mean value of the plateau. Soil δ13C is significantly correlated with soil carbon (C) content, C and N ratio and soil pH. Additionally, we found significant positive correlation between plant δ13C and MAT or MAP. Soil δ15N is negatively correlated with MAP but no relationship was revealed with MAT. In summary, our study highlights the importance of altitude induced MAT changes in the variation of plant δ13C and the independent control of MAP in the variation of both plant δ13C and soil δ15N.
Digit topology circles and their isomorphism identification for deriving topology graphs and creating complex closed mechanisms
Authors: Lu Yi , Lu Yang 
Published: August 2024

Abstract

The topology graph is an effective tool for creating various complex mechanisms and machines. However, the derivation and the isomorphism identification of the topology graphs are quite complicated because topology graphs may include (binary, ternary,...) links. A digit topology circle Cj(k)i excluding (binary, ternary) links is proposed and studied for simplifying the derivation and isomorphism identification of the topology graph. First, the conceptions of Cj(k)i are explained and their derivations are studied. Second, a method of the character strings is proposed and studied for representing Cj(k)i and reducing the isomorphism Cj(k)i, and many different Cj(k)i are represented by different digit lines and digit arcs based on the proposed method, and many different Cj(k)i are constructed. Third, a rule for identifying isomorphism Cj(k)i is discovered and proved using the connections in the digit topology circle, and some isomorphism Cj(k)i are identified from constructed different Cj(k)i. Furth, many new different Cj(k)i with the ternary link are derived by adding ternary link into Cj(k)i. Finally, a closed mechanism of 6-DOF the hybrid machine tool/hybrid grasper is created by combining 37 binary links with the new digit topology circle C3(2)10 + ternary link; two closed mechanisms of the 6-DOF leg-foot are created by combining 46 binary links with digit topology circles C26(1)i (i = 101,104), respectively.
Production of novel theranostic nano-vector based on superparamagnetic iron oxide nanoparticles/miR-497 targeting colorectal cancer
Authors: Elfiky Asmaa M. , Eid May M. , Manawaty May , Elshahid Zeinab A. , Youssef Elham Mohamed , Mahmoud Khaled 
Published: August 2024

Abstract

Colorectal cancer (CRC) is a serious public health concern worldwide. Immune checkpoint inhibition medication is likely to remain a crucial part of CRC clinical management. This study aims to create new super paramagnetic iron oxide nano-carrier (SPION) that can effectively transport miRNA to specific CRC cell lines. In addition, evaluate the efficiency of this nano-formulation as a therapeutic candidate for CRC.
Methods:Bioinformatics tools were used to select a promising tumor suppressormiRNA (mir-497-5p). Green route, using Fusarium oxyporium fungal species, manipulated for the synthesis of SPION@Ag@Cs nanocomposite as a carrier of miR-497-5p. That specifically targets the suppression of PD1/PDL1 and CTLA4pathways for colorectal therapy. UV/visible and FTIR spectroscopy, Zeta potential and MTT were used to confirm the allocation of the miR-497 on SPION@Ag@Cs and its cytotoxicity against CRC cell lines.
Results: Immunofluorescence was employed to confirm transfection of cells with miR-497@NPs, and the down- regulation of CTLA4 in HT29, and Caco2 cell lines. On the other hand, PDL1 showed a significant increase in colorectal cell lines (HT-29 and Caco-2) in response to mir497-5p@Nano treatment.
Conclusions: The data suggest that the mir-497 -loaded SPION@Ag@Cs nano-formultion could be a good candidate for the suppression of CTLA4in CRC human cell lines.Consequently, the targeting miR-497/ CTLA4 axis is a potential immunotherapy treatment strategy for CRC.
Reliability and Uncertainty-Aware Optimization of Capacitors and DSTATCOM Using Improved Exponential Distribution Optimizer
Authors: Alanazi Abdulaziz , Alanazi Mohana , Memon Zulfiqar Ali , Awan Ahmed Bilal , Deriche Mohamed 
Published: August 2024

Abstract

In this paper, the simultaneous optimization of capacitors and DSTATCOM in the radial distribution system is performed for minimizing the cost of network active losses along with the cost of installation and investment of reactive power, considering the reliability of compensators and incorporating the network load uncertainty. The decision variables include the installation location and the capacity of compensators, which is defined by a novel meta-heuristic algorithm termed the improved exponential distribution optimizer (IEDO). The conventional exponential distribution optimizer (EDO) is inspired by exponential distribution theory, which uses the spiral motion strategy in the EDO to improve optimization performance and prevent it from getting trapped in local optima. Simulation scenarios are implemented in three cases: I) capacitor optimization, II) DSTATCOM optimization, and III) simultaneous optimization of capacitor and DSTATCOM in the network without (scenario I) and considering the compensator's reliability and also the load uncertainty using the unscented transformation (scenario II). The simulation results of IEDO showed that Case III has the best performance by achieving the lowest cost, the highest percentage of net savings, and the most favorable voltage profile in comparison to other scenarios. The superiority of the IEDO has also been confirmed in contrast to widely recognized optimization methodologies. In addition, the results of Scenario II are clear: the system cost has increased by 8.76%, 8.79%, and 8.72%, and the net savings have decreased to 6.48%, 6.62%, and 6.42%, compared to Scenario I for cases I–III, respectively.
Patient and provider perspectives on pain and other dimensions of anesthesia experience for cesarean delivery: A qualitative study
Authors: Park Yunseo Linda , Clifton Briana , Ashraf Rida , Barlow Rose , Anderson Alexandra , Altamirano Valeria , Miller Emily , Neuman Mark , Lim Grace 
Published: August 2024

Abstract

Background: There is a lack of evidence on the importance of pain or other aspects of clinical care in the overall patient experience and patient-centered outcomes in cesarean delivery. The purpose of this study was to discover patient priorities in cesarean delivery anesthesia experience, to compare patient and provider perspectives, and to explore attitudes on shared decision-making around anesthesia choices for cesarean delivery.
Methods: Patients with recent cesarean deliveries and clinical care providers were approached using a purposeful sampling strategy for this prospective observational qualitative study. Patients were included if they were in the hospital within 72 hours of a cesarean delivery (scheduled or unscheduled), spoke English fluently, and had term gestation. Providers were included if they currently provide regular clinical care to patients having cesarean deliveries and have at least 3 years of practice experience. Semi-structured interviews were conducted using an interview guide. Interview transcripts were independently coded by three coders and qualitatively analyzed for major themes until thematic saturation was achieved.
Results: A total of 42 participants (20 patients and 22 providers) completed interviews. Five major themes emerged reflecting patient attitudes and beliefs toward cesarean delivery experience: 1) effective communication, education, and respect; 2) emotional support by care team; 3) intraoperative pain or discomfort; 4) varying acceptability around pain therapies; 5) stigma surrounding cesarean delivery. Five major themes emerged reflecting provider attitudes and beliefs toward cesarean delivery priorities: 1) complexity of pain responses; 2) multiple pain control strategies; 3) effective communication during emergency cesarean delivery; 4) patient psychological well-being during cesarean delivery; 5) barriers to observing the patients’ birth plans.
Conclusions: Patients and providers alike prioritize pain management, psychological well-being, and effective communication during cesarean delivery experiences. Patients emphasize relationships and trust in their cesarean experience, while clinicians emphasize clinical complexities and physical treatments. Our results guide future research in patient perspectives in cesarean deliveries.
Quantitative serum proteomic analysis for biomarker discovery in post-COVID-19 Postural Orthostatic Tachycardia Syndrome (PC-POTS) patients
Authors: Ryu Taekyung , Adler Brit , Jeong Seeun Judy , Lee David C. , Hoke Ahmet , Na Chan-Hyun , Chung Tae Hwan 
Published: August 2024

Abstract

Postural orthostatic tachycardia syndrome (POTS) is a chronic, debilitating condition that is characterized by an excessive increase in heart rate upon orthostatic challenge. Before the COVID-19 pandemic, POTS affected 0.5% to 1% of the U.S. population. Since the pandemic, the incidence has risen sharply, adding an estimated 6-7 million new cases in the U.S. Despite its importance, there is currently no reliable biomarker for POTS, leading to significant diagnostic delays. A major hurdle in identifying biomarkers is the heterogeneous nature of the syndrome. To address this, we focused on a homogeneous subgroup of post-COVID-19 POTS (PC-POTS) patients. We conducted quantitative proteomics on sera from 9 PC-POTS patients and 9 healthy controls, identifying 31 proteins with significantly different abundances in PC-POTS patients. Most elevated proteins were linked to actin filaments or immune functions/inflammation. Weighted Gene Co-Expression Network Analysis revealed module 7 (M7) correlated strongly with PC-POTS diagnosis and related traits. The key proteins in M7 included MTPN, TAGLN2, ADP-ribosylation factor 1, PDLIM1, PPIA, CNN2, LGALSL, TXN, TLN1, TUBA4A, IL4, TREML1, GP1BA, and, all highly correlated with these traits. Cell-type enrichment analysis revealed that M7 was highly associated with immune and neuronal cells. The main pathways identified in M7 included the integrin signaling pathway, blood coagulation, and glycolysis. These findings suggest that the key proteins in M7 could serve as biomarkers for PC-POTS. This study uses quantitative proteomics to identify potential biomarkers that differentiate PC-POTS patients from healthy controls, establishing a foundation for further research and validation.
Decoding the Genetic Comorbidity Network of Alzheimer's Disease
Authors: Zhang Xueli , Li Dantong , Ye Siting , Liu Shunming , Ma Shuo , Li Min , Peng Qiliang , Hu Lianting , Shang Xianwen , He Mingguang , Zhang Lei 
Published: August 2024

Abstract

Alzheimer's disease (AD) has emerged as the most prevalent and complex neurodegenerative disorder among the elderly population. However, the genetic comorbidity etiology for AD remains poorly understood. In this study, we conducted pleiotropic analysis for 41 AD phenotypic comorbidities, identifying ten genetic comorbidities with 16 pleiotropy genes associated with AD. Through biological functional and network analysis, we elucidated the molecular and functional landscape of AD genetic comorbidities. Furthermore, leveraging the pleiotropic genes and reported biomarkers for AD genetic comorbidities, we identified 50 potential biomarkers for AD diagnosis. Our findings deepen the understanding of the occurrence of AD genetic comorbidities and provide new insights for the search for AD diagnostic markers.
Cross-country inequalities in global burden of gastrointestinal cancers: a slope and concentration index methods
Authors: Zhou Haoyun , Wang Yongbo , Wang Fang , Meng Runtang , Yu Yong , Han Su , Zhang Yu , Wu Yu , Liu Xiaoxue 
Published: August 2024

Abstract

Purpose
To explore cross-country inequalities in global disease burdens of colon and rectum cancer (CRC), esophageal cancer (EC) and gastric cancer (GC).
Methods
Data from the Global Burden of Diseases Study 2019 were analyzed to examine trends in disability-adjusted life-years (DALYs) for three cancers using Estimated Annual Percentage Change (EAPC) and Joinpoint analysis. Inequality in DALYs rates was assessed with the Slope Index of Inequality and the Concentration Index, based on the Socio-Demographic Index (SDI).
Results
From 1990 to 2019, age standardized DALYs rate of CRC decreased in high and high-middle SDI regions, with the EAPC values of -1.018 and − 0.161, but increased among low, low-middle and middle SDI regions (EAPC = 1.035, 0.926 and 0.406, respectively). The DALYs rates of EC and GC decreased in all SDI regions. For CRC, the slope index changed from 358.42 (95% confidence interval: 343.28 to 370.49) to 245.13 (217.47 to 271.24); from − 63.88 (-87.48 to -48.28) to -1.36 (-32.44 to 25.87) for EC; from 126.37 (101.97 to 146.47) to 58.04 (20.54 to 96.12) for GC. The concentration index for CRC moved from 29.56 (28.99 to 29.84) to 23.90 (23.19 to 24.26); from − 9.47 (-10.30 to -9.24) to -14.64 (-15.35 to -14.24) for EC; from 8.44 (7.85 to 8.72) to -6.42 (-7.65 to -6.12) for GC.
Conclusion
This study suggests strong heterogeneity in global DALYs for gastrointestinal cancers across different SDI regions. Higher SDI regions faced a greater burden of CRC, while the burdens of EC and GC were more prevalent in lower SDI regions.
Priority of factors affecting the implementation of vaginal birth after Cesarean in Isfahan based on Talbot and Verrinder model
Authors: Jahani Zahra , Valiani Mahboubeh , Mansourian Marjan , Zafaranzadeh Nahid 
Published: August 2024

Abstract

Introduction: Today, Cesarean section, as a normal surgical procedure, is accompanied by maternal and fetal complications. The most common reason mentioned for high cesarean section rates is the repeat Cesarean section. Vaginal birth after Cesarean (VBAC) is an alternative to repeat Cesarean section. The first step to investigate VBAC status and plan to improve it in Isfahan city is to know and prioritize the attitude of key individuals.
Method: This cross-sectional study is a multi-method study (April, 2023 to August, 2023) conducted in Isfahan with participation of 75 Health Managers in the field of Treatment and Health Deputy, gynecologists and midwives, and 75 pregnant women. The eligible women were selected using a quota sampling method, and managers, gynecologists and midwives were selected using a convenience sampling method. Research instruments included the Attitude towards the Mode of Delivery Questionnaire and Factors Affecting the Choice of Type of Delivery Questionnaire developed by Valiani et al. The collected data were analyzed with SPSS software version 26.00 and using descriptive statistics and t-test Statistical tests.
Findings: As the gynecologists achieved lower scores in the third quartile than the key individuals (pregnant women, midwives, and health managers), the interventions to change their attitudes are of higher priority. There was a statistically significant relationship between the mothers' attitude mean score and their number of child delivery (p<0.05). A statistically significant relationship was also observed between the gynecologists' attitudes and their work experience (p<0.05).
Conclusion: Although teamwork in performing VBAC is essential, mothers are the final decision makers in performing VBAC. In planning for VBAC, measures thus should be taken to change mothers' attitudes, remove barriers, and obtain their consent to perform VBAC guidelines.
Interpreting Weekly External Load in Professional Soccer: A Position-Based and Context-Driven Approach for the “Real World” Setting
Authors: Gonçalves Luiz Guilherme , Silva Rui Miguel , Moraes-Neto Maxwell Viana , Pasquarelli Bruno , Pastor Alejandro , Leitão Rodrigo Aparecido Azevedo , Augusto Diêgo , Vasconcellos Fabrício , Aquino Rodrigo 
Published: August 2024

Abstract

Purpose
This study analyzed the weekly external load of professional soccer players with two main aims: 1) to describe the external load based on match-contextual difficulty and playing position; 2) to compare the external load in contexts of low and high match-contextual difficulty.
Methods
Eighteen professional soccer players were monitored over 13 weeks using GPS units and accelerometers. Players participating for at least 60 minutes in non-congested weeks were analyzed for total distance, distances covered at various speeds and acceleration levels, and Player Load. Match difficulties were categorized as "high" (score > 10) or "low" (score ≤ 10) and determined using match location and quality of opposition.
Results
The results revealed that the highest external loads occurred mid-week, decreasing towards the week's end, with external defenders and midfielders facing higher demands than central defenders and forwards. In low-difficulty scenarios (p < 0.001–0.030), external loads were higher than in high-difficulty scenarios, particularly on days preceding a match (MD-4 to MD-2). Conversely, high-difficulty matches increased distance and mechanical work on specific days (MD-3 and MD-1) (p < 0.001–0.020).
Conclusion
The findings suggest that external load varies significantly with match context, offering valuable insights for tailoring training loads according to position and upcoming match difficulty.
Design and Implementation of Electronic Sub-systems for the STAJe- Phase 1 Payload
Authors: Shelar Sampada Vijay , Paull Allan 
Published: August 2024

Abstract

STAJe- Phase 1 is a University of Queensland flight program that implements cost effective commercially off-the-shelf (COTS) hardware component which aims to demonstrate high speed (Mach 3–5) electric propulsions. This paper concentrates on the design and manufacturing of customable printed circuit boards which are required to integrate with the mechanical design. It is an example of interdisciplinary collaboration made simple by using modern design and manufacturing approaches. These approaches also allow for rapid manufacturing and ground testing of the system. The functionality and challenges with the mechanical interfaces of each electronic sub-system for STAJe- Phase 1 payload is discussed within a framework of predefined scientific requirements.