bluuebunny/crossref_metadata_2025_split huggingface dataset:
Integration of the medical information systems for the risk groups of the congenital pathologies formation
Authors: Kobrinsky Boris , Lupin Sergey , Ponomareva Natalia 
Published: February 2013

Abstract
Problem of formation the risk groups of the congenital pathologies needs in a close collaboration between medicine and IT technologies. Article reviews the formal apparatus based on the set-theoretical approach to the information systems, which allow assessment of their integration methods and prediction features. One of these integration methods was implemented on practice by authors during the creation of the medical integrated IS, designed for the Moscow district genetic center in Zelenograd.
Changes in strength abilities of adolescent girls: the effect of a 3-year physical education curriculum
Authors: Czarniecka Renata , Milde Katarzyna , Tomaszewski Paweł 
Published: February 2013

Summary

Study aim: To evaluate changes in strength abilities of adolescent girls that underwent a 3-year physical education
curriculum.

Material and methods: The research participants comprised 141 girls aged 13.3 ± 0.35 years who participated in a 3-
year physical education curriculum (PEC). Evaluation was based on the following EUROFIT Testing Battery tests:
standing broad jump, handgrip strength, sit-ups, and bent arm hang. After the completion of the curriculum, changes
in strength abilities of the participants were evaluated. Test results were compared to reference values for the population
of Polish girls.

Results: After the 3-year PEC, research participants obtained significantly better results in all analyzed tests. At the
beginning of the PEC, participants performed significantly worse in comparison to the reference values for the standing
broad jump and bent arm hang tests, and better in the handgrip strength test. After the completion of the PEC, the participants
performed significantly better in the sit-up and handgrip strength tests compared to reference values; for the
standing broad jump and bent arm hang tests, they performed closer to the reference values.

Conclusions: While the development of student physical fitness is achievable through physical education lessons at
school, innovative teaching methods and professional and creative approaches on the part of teachers are necessary.
Prevalence of faulty posture in children and youth from a rural region
in Iran
Authors: Gh Maghsoud Eivazi , Alilou Amin , Ghafurinia Solmaz , Fereydounnia Sara 
Published: February 2013

Summary

Study aim: To assess the presence of musculoskeletal deformities in lower extremities and to detect faulty posture in
schoolchildren living in a rural region of Iran.

Material and methods: 172 schoolchildren aged 5-20 years, including 66 boys and 106 girls were screened deviations
in the musculoskeletal system. Furthermore, the postural muscles including the hamstring and gastroc-soleus were
examined for finding any shortness.

Results: The prevalence of cervical lordosis (22.6% vs. 6.1%), forward head posture (24.1% vs. 9.1%) and thoracic
kyphosis (27.8 % vs. 7.6%) was significantly higher in girls than in boys. The prevalence of cervical lordosis, FHP,
thoracic kyphosis, and genu varum increased with age; in the case of genu valgum, the situation was reversed. Genu
varum was almost twice as frequent in girls as in boys (44.4% vs. 25.8%; p<0.01), while the genu valgum was more
frequent (p<0.001) in boys than in girls (13.6 and 2.8, respectively). No significant age or gender-dependent differences
were found for hamstring shortness (29%), gastroc-soleus shortness (21%), genu recurvatum (22%), and hallux
valgus (31%).

Conclusions: Faulty posture and lower limb deformities were highly prevalent in school children in this rural region.
More attention should be paid to implementing school-based screening programs aimed at early detection of any
musculoskeletal-related abnormalities and taking preventive steps to reduce their negative consequences.
Innovative Improvement and Intensification of Business Relationships Supported by Cooperative Networks
Authors: Vančová Viera , Čambál Miloš , Cagáňová Dagmar 
Published: February 2013

Abstract
Nowadays, the opportunity for companies to be involved in cluster initiatives and international business associations is a major factor that contributes to the increase of their innovative potential. Companies organized in technological clusters have greater access to mutual business contacts, faster information transfer and deployment of advanced technologies. These companies cooperate more frequently with universities and research - development institutions on innovative projects.
An important benefit of cluster associations is that they create a suitable environment for innovation and the transfer of knowledge by means of international cooperation and networking. This supportive environment is not easy to access for different small and mediumsized companies, who are not members of any clusters or networks. Supplier-customer business channels expand by means of transnational networks and exchanges of experience. Knowledge potential is broadened and joint innovative projects are developed. Reflecting the growing importance of clusters as driving forces of economic and regional development, a number of cluster policies and initiatives have emerged in the last few decades, oriented to encourage the establishment of new clusters, to support existing clusters, or to assist the development of transnational cooperation.
To achieve the goals of the Europe 2020 Strategy, European countries should have an interest in building strong clusters and developing cluster cooperation by sharing specialized research infrastructures and testing facilities and facilitating knowledge transfer for crossborder cooperation. This requires developing a long term joint strategy in order to facilitate the development of open global clusters and innovative small and medium entrepreneurs.
Age and Gender Specific Variations in Attitudes to Performance Enhancing Drugs and Methods. A Cross-Sectional Study
Authors: Singhammer John 
Published: February 2013

Abstract
Background: Little is known about age and gender specific attitudes to performance enhancing drugs and methods or other characteristics by which attitudes may vary. Methods: Using a population based cross-sectional sample of 1,703 Danish men and women aged 15-60 years, the present study examined age and gender variation in attitudes to performance enhancing drugs and methods. Response rate was 34 %. Information on attitudes was collected by questionnaire. Results: Overall, participants held negative attitudes to drugs and methods enhancing predominantly cognitive abilities enhancing performance drugs and to appearance modifying methods, but were positive to drugs for restoring physical functioning conditions. However, attitudes varied nonlinearly across age. Lenient attitudes peaked at age around 25 and subsequently decreased. Lenient attitudes to use of drugs against common disorders decreased in a linear fashion. No gender differences were observed and attitude did not vary with level of education, self-reported health or weekly hours of physical activity. Conclusion: The present study expands existing knowledge about attitudes toward PEDM with respect to age and gender specific differences. Future studies should take age variations into account, when examining attitudes to PEDM in the general population.
A Lab Study on Speed of Self-defense Skills of American College Men and Women
Authors: Yu Jing , Liu Liu , Chen Gong 
Published: February 2013

Abstract
The purpose of this study was to investigate college students on their speed of performing different types of self-defense skills commonly taught in American university self-defense courses. The results indicated that close defense skills and distance punches are faster than distance kicks in most single skills or combination skills. Women can do most skills as fast as men. The results also indicated that all kicks with back-foot are slower than kicks with front-foot in distance defense. Women need 2.42- 6.12 seconds to escape from all 20 holds, while men need 1.14-5.54 seconds for people who successfully escaped. Escaping from different holds is not as difficult as what most people think. After proper learning and practice, a majority of college women and men can escape from many holds in 1-6 seconds.
Patterns of Verbal -s in the Varieties of English Today
Authors: Bismark Christina 
Published: February 2013

AbstractThe occurrence of the verbal ending -s with non-3rd person singular subjects is a frequent phenomenon in varieties of English worldwide. It has been attested to fulfil a wide range of functions in addition to its Standard English use as a person-number marker. This paper is to characterize the various factors which condition the use of nonstandard verbal -s. It will discuss their areal distribution and give an account of the frequency with which each of the conditioning factors is attested. Based on this characterization, a group of core constraints will be isolated, the specific character of which will be shown to have facilitated their stability, endurance and spread.
Macbeth in (the Shade of) Iraq: Crossing the Borders of Poland, Nato and the Defensive War
Authors: Fabiszak Jacek 
Published: February 2013

AbstractThe numerous Polish productions of Macbeth in an overt or covert fashion address issues that have been at the core of political debate in the past decade, such as the state’s engagement in military missions that are in fact real wars. Furthermore, they also comment on the new Polish political system (is it still “new”?) and the situation of individuals in it, how they can profit in it. The paper discusses productions such as Andrzej Wajda’s (2004) from the Stary Theatre in Kraków, Maja Kleczewska’s (2004) from the Kochanowski Theatre in Opole, Grzegorz Jarzyna’s (2005; the full title is “2007: Macbeth”) from the Teatr Rozmaitości (TR) in Warsaw, and Piotr Kruszczyński’s (2005) from the Polski Theatre in Warsaw.
Descriptions of the Body: Violence in the Subcultures of Contemporary Romanian Youth
Authors: Doboș Daniela 
Published: February 2013

AbstractFor a long time, with few exceptions, Romanian linguistics took no interest in native slang, but after 1990 this has made a dramatic comeback in more than one way. One of the crudest versions of new slang, with touches of violence and licentiousness, turning the unsayable into sayable, is that currently used by young Romanians. It has been justly argued that such linguistic outlet came as a logical consequence, after the demise of communism, of the former censorship and wooden tongue. The paper sets out to put this oft-deplored linguistic phenomenon into perspective and analyse the main linguistic means employed in shaping it up.
Suturing a Wounded Body—Wounded Mind in Red Silk on White Linen: Embodied and Hand(Y) Knowledge of Trauma
Authors: Goggin Maureen Daly 
Published: February 2013

AbstractIn 1830, Elizabeth Parker, daughter of a day laborer and of a teacher in Ashburnham, East Sussex, England, cross-stitched in red silk thread an extraordinarily complex text that participates in several genres, including a memoir of her then brief life of some seventeen years, a confession, a suicide note, and a prayer. These various genres cohere around one momentous event in Parker’s young life: the sexual violation and physical abuse at the hands of her employer, Lt. G. After suturing 46 lines, 1,722 words, and 6,699 characters, she stops mid-line and mid-way down her cloth with the powerful plea, “What will become of my soul[?]” This paper argues that Parker’s sampler was a robust site in which Parker was able to grapple with her wounded body and mind. To justify the claim that a woman’s stitching can be interpreted as an epistemic activity, the proposed paper turns to two key concepts “situated knowledges” and “embodied knowledge”- both of which have been posited by feminists as a way to destabilize the dominant validation of disembodied, abstract thinking where the eye serves as the mind’s tool of investigation. (Haraway; Knappett; Frank; Driver)
Incisional Hernia of Elective Midline Caesarean Section: Incidence and Risk Factors
Authors: Al-Dahamsheh Md Hasan 
Published: February 2013

Objective: To analyze the incidence and risk factors for development hernia after elective lower midline caesarean section(ElMCS).Method: A prospective cohort study of 284 women for development of incisional hernia after repeated elective midline CS. Patients enrollment done from April 13th 2001 and December 12th 2002. follow up to two years for hernia development. Hernias were identified radiographically or during physical exam. 2-year hernia rates were calculated. Patients were distributed in two groups, study group consisted of women who had incisional hernia and control group consisted from women who had not within 2-years postoperatively. Within the two groups potential risk factors (age, body mass index (BMI), parity, number of previous cesareans, chronic cough, diabetes mellitus(DM), heart disease, low serum albumin, type of previous incision, anesthesia type, presence of postoperative fever and wound complications) were collected and statistically analyzed with the development of incisional hernia (IH). Setting: Prince Hashem Ben Al-Hussein Hospital, Jordanian Royal Medical Services of Jordan / Zarqa. Results: The 2-year hernia was 5.6 % .Independent risk factors of IH development include: increase in number of previous CSs, wound complications and obesity. Conclusion: An incisional hernia is higher than previously estimated in women undergoing ElMCS. Counseling on the family size will reduce the chance for further CS with its associated risk. Also measures to reduce wound infection after surgery may reduce the incidence of incisional hernia following ElMCS. DOI: http://dx.doi.org/10.3329/bjog.v25i1.13724 Bangladesh J Obstet Gynaecol, 2010; Vol. 25(1) : 9-14
Serum Magnesium in Pre-eclampsia and Eclampsia
Authors: Nahar K , Yasmin H , Shamsuzzaman L 
Published: February 2013

Objective: To assess the serum magnesium level of pregnant women with pre-eclampsia and eclampsia in Mymensingh Medical College & Hospital (MMCH). Materials and Methods: This descriptive cross-sectional study was carried out in the department of Obstetrics and Gynaecology of Mymensingh Medical College & Hospital (MMCH) and  Prof. Muhammed Hossain Central Laboratory of Bangladesh Agricultural University (BAU). The serum magnesium level were estimated in 60 study subjects who were pregnant women with pre-eclampsia & eclampsia and of 60 control subjects who were the normotensive pregnant women by photometric test using xylidyl blue. Results: The mean (±SD) serum magnesium of the control and study group were (2.29 ± 0.28 mg/dl) & (1.84 ±0.26 mg/dl) respectively. The difference in serum magnesium level between the two groups was statistically highly significant (p=<0.001). In the study group the mean (±SD) serum magnesium level of the pre-eclamptic & eclamptic groups were (1.9150 ± 0.26 mg/dl) & (1.8063 ±0.25 mg/dl) respectively and the difference between them was also statistically significant (p=<0.05). Conclusion: From the result it could be concluded that hypomagnesaemia can be said to be one of the etiological factors in pre-eclampsia and eclampsia. Hence by estimating serum magnesium during antenatal period pre-eclampsia can be predicted and eclampsia can be prevented early. DOI: http://dx.doi.org/10.3329/bjog.v25i1.13725 Bangladesh J Obstet Gynaecol, 2010; Vol. 25(1) : 15-19
Spontaneous Rupture of Uterine Veins In Pregnancy
Authors: Shahnewaj KH , Al Sayed Md , Jabin Kauser 
Published: February 2013

Spontaneous rupture of uterine vessels during pregnancy is a rare cause of shock that has a high rate of maternal and foetal loss. Though the usual presentation is of maternal shock, it is necessary to have in mind that possibility of blood vessels rupture may be in cases of abdominal pain & hypotension of unknown origin during pregnancy. In such an event an exploratory laparatomy followed by caesarean with ligation of the uterine vessel or its branch can help in preventing a maternal mortality. The advent of modern resuscitative facilities, anaesthesia techniques have lowered mortality associated with this condition from 49% to 3.6%. DOI: http://dx.doi.org/10.3329/bjog.v25i2.13745 Bangladesh J Obstet Gynaecol, 2010; Vol. 25(2) : 85-86
A multilocus phylogenetic analysis of Escallonia (Escalloniaceae): Diversification in montane South America
Authors: Zapata Felipe 
Published: February 2013

• Premise of the study: The mountains of South America are hotspots of plant diversity. How this diversity originated and evolved, and what roles geographic and environmental factors may have played in the diversification of lineages occurring in these regions, is not well understood. Escallonia, a morphologically and ecologically diverse group of shrubs and trees widely distributed in these mountains, provides an ideal opportunity for studying the historical underpinnings that have shaped the extraordinarily distinctive, diverse, and endangered flora of these regions, and for evaluating the role of abiotic factors in the process of lineage divergence.• Methods: I analyzed neutral DNA sequence data from two nuclear loci and one chloroplast locus using maximum parsimony, maximum likelihood, and Bayesian phylogenetic approaches. I used a Bayesian approach to analyze the geographic structure of gene trees, and a phylogenetically controlled decomposition of the variance in bioclimatic variables to analyze the eco‐climatic structure of gene trees.• Key Results: I found that Escallonia (1) is monophyletic, (2) has a remarkable level of geographic and climatic phylogenetic structure, (3) likely originated in the tropical Andes, and (4) has a widespread absence of species exclusivity.• Conclusions: Geography played an important role early in the history of Escallonia by separating populations that later diversify likely in isolation. Although geographic isolation was generally accompanied by changes in climate, it is not clear whether environmental gradients along elevation have influenced more recent diversification events or whether species have evolved broader environmental tolerances.
Perceived Health Benefits from Yoga among Breast Cancer Survivors
Authors: Van Puymbroeck Marieke , Burk Brooke N. , Shinew Kimberly J. , Kuhlenschmidt Megan Cronan , Schmid Arlene A. 
Published: February 2013

Purpose. The purpose of this paper is to describe the health benefits reported by breast cancer survivors following an 8-week yoga intervention. Design. This phenomenological study employed three focus groups with six breast cancer survivors each (n = 18) following the yoga intervention. Setting. The focus groups and yoga classes were conducted in a large hospital in a midsized town in the Midwest. Subjects. Eighteen female breast cancer survivors who were at least 9 months posttreatment participated in the focus groups following the 8-week yoga intervention. Intervention. An 8-week yoga intervention designed specifically for this population was led by a yoga therapist. Measures. A semistructured interview guide was utilized to guide each focus group. Analysis. Interpretative phenomenological analysis methods were employed to explore breast cancer survivors' experiences after participating in an 8-week yoga intervention. Results. The findings revealed that the women in the study found health promoting benefits in the areas of physical health and healing, mental health and healing, and social health and healing. Conclusions. Yoga may be an important tool in the healing process for breast cancer survivors.
Daily Pedometer Steps among Older Men: Associations with Health-Related Quality of Life and Psychosocial Health
Authors: Vallance Jeff K. , Eurich Dean , Lavallee Celeste , Johnson Steven T. 
Published: February 2013

Purpose. To determine the associations of daily pedometer steps with health-related quality of life (HRQoL) and psychosocial health. Design. Cross-sectional. Setting. Alberta, Canada. Subjects. Three hundred eighty-five older-aged men 55 years of age and older. Measures. Subjects completed a mailed survey that assessed HRQoL (RAND-12 Health Status Inventory [RAND-12]), depression, anxiety, and satisfaction with life. Steps/day were assessed with a pedometer via a 3-day step-monitoring period. Analysis. Average pedometer steps/d were categorized into quartiles (Qs). The primary model assessed the association between average pedometer steps/d as the independent variable of interest and our dependent variables of interest (physical, mental, and global health component scores of the RAND-12). Results. For HRQoL, all three adjusted models (i.e., physical, mental, and global health) indicated a significant linear trend between HRQoL indices across pedometer step Qs, with participants in Q3 and Q4 demonstrating higher physical, mental, and global health compared to participants in the lowest Q of pedometer steps (Q1) (all p < .05). For depression, significant differences were observed between Q1 and Q3 (Mdiff = 3.3, p = .006, η2 = .019) and Q1 and Q4 (Mdiff = 2.7, p = .025, η2 = .013). Conclusion. Higher average steps/d were significantly associated with HRQoL across all domains. Older men in the higher Qs of pedometer steps/d reported less depressive symptoms compared to those in the lowest Q of pedometer steps/d.
Targeted Alpha-Particle Immunotherapy with Bismuth-213 and Actinium-225 for Acute Myeloid Leukemia
Authors: Jurcic Joseph G 
Published: February 2013

ABSTRACT
Lintuzumab, a humanized anti-CD33 antibody, targets myeloid leukemia cells and has modest activity against acute myeloid leukemia (AML). To increase the antibody's potency yet avoid nonspecific cytotoxicity seen with β-emitting isotopes, lintuzumab was conjugated to the α-emitters bismuth-213 (213Bi) and actinium-225 (225Ac). The 46-minute half-life of 213Bi limits its widespread use. Therefore, 225Ac was also conjugated to various antibodies using DOTA-SCN. We conducted a phase I trial of 213Bi-lintuzumab and subsequently administered cytarabine with 213Bi-lintuzumab in a phase I/II study. The toxicity and biological activity of 225Ac-linutuzumab in patients with relapsed/refractory AML in a phase I dose-escalation trial was determined. An initial phase I trial demonstrated the feasibility, safety and antileukemic activity of 213Bi-lintuzumab. 213Bi-lintuzumab produced responses in 24% of AML patients receiving doses ≥ 37 MBq/kg after partial cytoreduction with cytarabine. 225Ac-labeled immunoconjugates killed in vitro at doses at least 1,000 times lower than 213Bi analogs. Eighteen patients with relapsed/refractory AML received 18.5 to 148 kBq/kg of 225Ac-lintuzumab in a phase I study. Dose-limiting toxicities were myelosuppression lasting >35 days in one patient and death due to sepsis in two patients. The maximum tolerated dose (MTD) was 111 KBg/kg. Bone marrow blast reductions were seen across all dose levels. Targeted α- particle immunotherapy with 213Bi- and 225Ac-lintuzumab is safe, has significant antileukemic effects, and can produce remissions after partial cytoreduction.

How to cite this article
Jurcic JG. Targeted Alpha-Particle Immunotherapy with Bismuth-213 and Actinium-225 for Acute Myeloid Leukemia. J Postgrad Med Edu Res 2013;47(1): 14-17.