bluuebunny/crossref_metadata_2025_split huggingface dataset:
Netmums: a phase II randomized controlled trial of a guided Internet behavioural activation treatment for postpartum depression
Authors: O'Mahen H. A. , Richards D. A. , Woodford J. , Wilkinson E. , McGinley J. , Taylor R. S. , Warren F. C. 
Published: October 2013

BackgroundDespite the high prevalence of postnatal depression (PND), few women seek help. Internet interventions may overcome many of the barriers to PND treatment use. We report a phase II evaluation of a 12-session, modular, guided Internet behavioural activation (BA) treatment modified to address postnatal-specific concerns [Netmums Helping With Depression (NetmumsHWD)].MethodTo assess feasibility, we measured recruitment and attrition to the trial and examined telephone session support and treatment adherence. We investigated sociodemographic and psychological predictors of treatment adherence. Effectiveness outcomes were estimated with the Edinburgh Postnatal Depression Scale (EPDS), Generalized Anxiety Disorder-7, Work and Social Adjustment Scale, Postnatal Bonding Questionnaire, and Social Provisions Scale.ResultsA total of 249 women were recruited via a UK parenting site, Netmums.com. A total of 83 women meeting DSM-IV criteria for major depressive disorder were randomized to NetmumsHWD (n = 41) or treatment-as-usual (TAU; n = 42). Of the 83 women, 71 (86%) completed the EPDS at post-treatment, and 71% (59/83) at the 6-month follow-up. Women completed an average of eight out of 12 telephone support sessions and five out of 12 modules. Working women and those with less support completed fewer modules. There was a large effect size favouring women who received NetmumsHWD on depression, work and social impairment, and anxiety scores at post-treatment compared with women in the TAU group, and a large effect size on depression at 6 months post-treatment. There were small effect sizes for postnatal bonding and perceived social support.ConclusionsA supported, modular, Internet BA programme can be feasibly delivered to postpartum women, offering promise to improve depression, anxiety and functioning.
People like us? Social status, social inequality and perceptions of public rental housing
Authors: FORREST RAY , WU YING 
Published: October 2013

AbstractOver the last three decades or so, neoliberal policies have had a significant effect on housing sectors across a wide range of societies. State rental sectors, in particular, have been in the ideological firing line. Portrayed as inefficient, unresponsive, monopolistic and anachronistic, they have been typically marketised, privatised and downsized. At the same time, wider societal changes have impacted on their social role and social composition. The overall effect on many public rental sectors is now very familiar – growing social and spatial segregation, enclaves of concentrated and multiple disadvantage and increased stigmatisation. Against this background, Hong Kong's public rental sector has survived relatively unscathed and continues to accommodate around a third of its households. This paper examines the experiences and perceptions of Hong Kong public rental housing among those within and outside the sector. How are public tenants perceived in relation to ideas of social status and social equality? How do public tenants see themselves? The paper draws on a survey of 3,000 individuals in Hong Kong which is part of a larger study concerned with housing provision and social change in the Special Administrative Region.
Ligand binding and complex formation of galectin-3 is modulated by pH variations
Authors: von Mach Tobias , Carlsson Michael C. , Straube Tamara , Nilsson Ulf , Leffler Hakon , Jacob Ralf 
Published: October 2013

Galectin-3-dependent clusters or lattices are formed at the surface as well as in distinct organelles of eukaryotic cells. Incorporation into membrane proximal networks can fix glycoproteins within subcellular domains or sort them into distinct transport pathways. In the present paper we analysed the effect of acidification on the sugar binding and self-oligomerization of galectin-3. Using a fluorescence anisotropy assay we measured decreasing galectin-3 affinities to the blood group antigen GalNAcα1-3(Fucα1-2)Galβ1-4Glc under low pH conditions. Binding to the strong interaction partner N-acetyl-D-lactosamine was also lost at pH 5.0, whereas the less efficient ligand lactose was still able to bind. This indicates that variations in the binding specificity to distinct glycans can be observed by altering the pH. The formation of galectin-3-based complexes by interaction with the multivalent glycoproteins asialofetuin or transferrin was also obliterated at acidic pH and the ligand-binding affinity itself was modulated by oligomerization of the lectin. When galectin-3 was added to giant plasma membrane vesicles from the apical surface of epithelial cells, pH modulation could generate or eliminate the formation of membrane domains enriched with p75NTR (neurotrophin receptor p75). In conclusion, the results of the present study suggest that the formation and composition of galectin-3 networks can be fine-tuned by changes in the environmental pH.
Flexible radio frequency connectors for textile electronics
Authors: Seager R.D. , Chauraya A. , Zhang S. , Whittow W. , Vardaxoglou Y. 
Published: October 2013

A new approach to interfacing fabric based wireless systems to traditional electronics circuitry is presented. Measurements show possible insertion losses of the connector to be < 1 dB up to frequencies of about 4 GHz when electroplating has been used to increase the hook and loop conductivities. This reported work points towards an interconnection system that is flexible and will allow the removal and replacement of conventional electronics connected to textile based systems.
Recent measurements of compact electronically tunable liquid crystal phase shifter in rectangular waveguide topology
Authors: Weickhmann C. , Nathrath N. , Gehring R. , Gaebler A. , Jost M. , Jakoby R. 
Published: October 2013

A low‐weight, compact, tunable phase shifter based on liquid crystal technology is presented. It is designed in a hollow waveguide topology with a dielectric filled cross‐section. The operational frequency range is 21–29 GHz, but data up to 35 GHz have been obtained and are presented. The device offers more than 140° phase shift peak per dB insertion loss and 110–130°/dB in the desired range.
Broadband RCS reduction and high gain waveguide slot antenna with orthogonal array of polarisation‐dependent AMC
Authors: Zhao Yi , Cao Xiang‐yu , Gao Jun , Li Wen‐qiang 
Published: October 2013

A novel design for broadband radar cross‐section (RCS) reduction and a high gain waveguide slot antenna is proposed. The orthogonal array of a polarisation‐dependent artificial magnetic conductor (AMC) is exploited and contributes to the scattering and radiation improvement. The measured results demonstrate that, compared with the conventional antenna with a metallic plate, the novel antenna achieves a 20% relative bandwidth of 10 dB RCS reduction and 3.2 dB gain enhancement.
High‐data‐rate FSK demodulator for wireless communication
Authors: Zhou Haifeng , Shum Kam Man , Cheung Ray C.C. , Chan Chi‐Hou 
Published: October 2013

A low‐power frequency‐shift keying (FSK) demodulator capable of demodulating 5 Mbit/s data rate is presented. No high sampling clock is needed in this demodulator design, and thus the design not only greatly reduces the circuit complexity but also achieves a high data rate. It is suitable for a digital data transmission chain of wireless communication.
Si wire array waveguide grating with stray light reduction scheme fabricated by ArF excimer immersion lithography
Authors: Okayama H. , Shimura D. , Onawa Y. , Takahashi H. , Seki M. , Koshino K. , Yokoyama N. , Oshtsuka M. , Tsuchizawa T. , Nishi H. , Yamada K. , Yaegashi H. , Horikawa T. , Sasaki H. 
Published: October 2013

A Si wire arrayed waveguide grating designed to reduce the noise and transmission peak width and avoid systematic phase error generated at the curved waveguides is reported. A slab waveguide structure to remove stray light is used. 200 GHz spacing 16 channel devices were fabricated by ArF immersion. An improved crosstalk of −23 dB was obtained.
Electrostatically driven and capacitively detected differential lateral resonant pressure microsensor
Authors: Jiao Hailong , Xie Bo , Wang Junbo , Chen Deyong , Chen Jian 
Published: October 2013

Presented is the design, fabrication and characterisation of an electrostatic‐driving and capacitive‐detection differential resonant pressure microsensor. The differential structure consists of two resonators immobilised on the diaphragm. In response to the pressure under measurement, the diaphragm deflection increases the intrinsic resonant frequency of one resonant beam and decreases the resonant frequency of the other. A differential frequency output reduces the common frequency drift caused by stresses and interferences, and thus improves the sensor's stability. The device geometries were optimised using numerical simulations and the fabrication process was based on a silicon‐on‐insulator wafer requiring only two masks with simplified microfabrication steps (e.g. sputter, wet etching and deep reactive ion etching). The sensor was quantified in an open‐loop characterisation platform, producing a quality factor higher than 10 430 in vacuum (< 0.5 Pa). Closed‐loop test results recorded a linear resonant frequency shift (a linear correlation of 0.9999) in response to applied pressure, with a sensitivity of 227 Hz/kPa. This resonant pressure microsensor has a simple fabrication process and reliable performance, and can be used for pressure monitoring in various locations including weather stations and aerospace.
Cell Growth Defect Factor1/CHAPERONE-LIKE PROTEIN OF POR1 Plays a Role in Stabilization of Light-Dependent Protochlorophyllide Oxidoreductase in Nicotiana benthamiana and Arabidopsis
Authors: Lee Jae-Yong , Lee Ho-Seok , Song Ji-Young , Jung Young Jun , Reinbothe Steffen , Park Youn-Il , Lee Sang Yeol , Pai Hyun-Sook 
Published: October 2013

Abstract
Angiosperms require light for chlorophyll biosynthesis because one reaction in the pathway, the reduction of protochlorophyllide (Pchlide) to chlorophyllide, is catalyzed by the light-dependent protochlorophyllide oxidoreductase (POR). Here, we report that Cell growth defect factor1 (Cdf1), renamed here as CHAPERONE-LIKE PROTEIN OF POR1 (CPP1), an essential protein for chloroplast development, plays a role in the regulation of POR stability and function. Cdf1/CPP1 contains a J-like domain and three transmembrane domains, is localized in the thylakoid and envelope membranes, and interacts with POR isoforms in chloroplasts. CPP1 can stabilize POR proteins with its holdase chaperone activity. CPP1 deficiency results in diminished POR protein accumulation and defective chlorophyll synthesis, leading to photobleaching and growth inhibition of plants under light conditions. CPP1 depletion also causes reduced POR accumulation in etioplasts of dark-grown plants and as a result impairs the formation of prolamellar bodies, which subsequently affects chloroplast biogenesis upon illumination. Furthermore, in cyanobacteria, the CPP1 homolog critically regulates POR accumulation and chlorophyll synthesis under high-light conditions, in which the dark-operative Pchlide oxidoreductase is repressed by its oxygen sensitivity. These findings and the ubiquitous presence of CPP1 in oxygenic photosynthetic organisms suggest the conserved nature of CPP1 function in the regulation of POR.
A Comparative Analysis of Risk Factors and Stroke Risk for Asian and Non-Asian Men: The Asia Pacific Cohort Studies Collaboration
Authors: Hyun Karice K. , Huxley Rachel R. , Arima Hisatomi , Woo Jean , Lam Tai Hing , Ueshima Hirotsugu , Fang Xianghua , Peters Sanne A. E. , Jee Sun Ha , Giles Graham G. , Barzi Federica , Woodward Mark 
Published: October 2013

Background The risk of stroke is high in men among both Asian and non-Asian populations, despite differences in risk factor profiles; whether risk factors act similarly in these populations is unknown. Aim To study the associations between five major risk factors and stroke risk, comparing Asian with non-Asian men. Methods We obtained data from the Asia Pacific Cohort Studies Collaboration, a pooled analysis of individual participant data from 44 studies involving 386 411 men with 9·4 years follow-up. Using cohorts from Asia and Australia/New Zealand Cox models were fitted to estimate risk factor associations for ischemic and haemorrhagic stroke. Results We identified significant, positive associations between all five risk factors and risk of ischemic stroke. The associations between body mass index, smoking, and diabetes with ischemic stroke were comparable for men from Asia and Australia/New Zealand. The association between systolic blood pressure and ischemic stroke was stronger for Asian than Australia/New Zealand cohorts, whereas the reverse was true for total cholesterol. For haemorrhagic stroke, only systolic blood pressure and smoking were associated with increased risk, although the relationship with systolic blood pressure was significantly stronger for men from Asia than Australia/New Zealand ( Pinteraction = 0·03), whereas the reverse was true for smoking ( Pinteraction = 0·001). There was an inverse trend of total cholesterol with haemorrhagic stroke, significant only for Asian men. Conclusions Men from the Asia-Pacific region share common risk factors for stroke. Strategies aimed at lowering population levels of systolic blood pressure, total cholesterol, body mass index, smoking, and diabetes are likely to be beneficial in reducing stroke risk, particularly for ischemic stroke, across the region.
A national cross‐sectional study measuring predictors for improved service user outcomes across clinical nurse or midwife specialist, advanced nurse practitioner and control sites
Authors: Comiskey Catherine , Coyne Imelda , Lalor Joan , Begley Cecily 
Published: October 2013

AbstractAimThe aim was to identify key patient outcomes and to compare these outcomes across services that employed clinical specialists (either nurse or midwife) or advanced nurse practitioners with matched, non post‐holding services.BackgroundIn nursing and evaluation research, it is recognized that, further patient outcome studies, which measure and evaluate the impact of the new advanced roles, are urgently needed.DesignA cross‐sectional study design with a comparison group was implemented across Ireland.MethodA total of 279 surveys were completed by service users in 41 services in 2009/10. Key outcomes were identified, then chosen as primary outcomes and assessed for differences across post‐holding and the matched comparison sites. To identify the priority of importance of the key outcomes, a logistic regression model was computed with difference in overall care observed (yes or no) as the dependent variable, and gender, age grouping and the key outcomes as the independent predictors.ResultsAnalysis revealed that the key outcomes were, on anxieties, dignity and respect, time waited, confidence in the clinician and the clinician making a positive difference. Results of the logistic modelling of the key outcome on noticing any difference in the care given by the clinical specialists or advanced nurse practitioners compared with the care from others revealed that the single most important predictor was being treated with respect.ConclusionFurther studies evaluating advanced health professions roles measuring these six key outcomes, at a minimum, will ensure that service users' main concerns are being accounted for.
Money, Margins and the Motors of Politics: The EU and the Development of Party Politics in Central and Eastern Europe
Authors: Haughton Tim 
Published: October 2013

AbstractIn line with expectations EU membership has only a limited impact on party politics in the new Member States of central and eastern Europe (CEE); even the economic crisis has not altered this level of impact. An examination of party positioning, party appeals and party competition indicates the EU plays the role of a boundary keeper, a reference point and a weapon to be invoked in domestic competition, particularly to lambast opponents for their incompetence, especially when it comes to the ability to access and manage EU funds. Underlying parties' stances on European integration are the deep‐rooted vulnerabilities which help explain why the CEE states recognize the necessity of co‐operation and a pooling of sovereignty at the European level.
Work‐based assessment: qualitative perspectives of novice nutrition and dietetics educators
Authors: Palermo C. , Beck E. J. , Chung A. , Ash S. , Capra S. , Truby H. , Jolly B. 
Published: October 2013

AbstractBackgroundThe assessment of competence for health professionals including nutrition and dietetics professionals in work‐based settings is challenging. The present study aimed to explore the experiences of educators involved in the assessment of nutrition and dietetics students in the practice setting and to identify barriers and enablers to effective assessment.MethodsA qualitative research approach using in‐depth interviews was employed with a convenience sample of inexperienced dietitian assessors. Interviews explored assessment practices and challenges. Data were analysed using a thematic approach within a phenomenological framework. Twelve relatively inexperienced practice educators were purposefully sampled to take part in the present study.ResultsThree themes emerged from these data. (i) Student learning and thus assessment is hindered by a number of barriers, including workload demands and case‐mix. Some workplaces are challenged to provide appropriate learning opportunities and environment. Adequate support for placement educators from the university, managers and their peers and planning are enablers to effective assessment. (ii) The role of the assessor and their relationship with students impacts on competence assessment. (iii) There is a lack of clarity in the tasks and responsibilities of competency‐based assessment.ConclusionsThe present study provides perspectives on barriers and enablers to effective assessment. It highlights the importance of reflective practice and feedback in assessment practices that are synonymous with evidence from other disciplines, which can be used to better support a work‐based competency assessment of student performance.
The Green Economy Mirage?
Authors: Chao Chia‐Wei , Ma Hwong‐wen , Heijungs Reinout 
Published: October 2013

SummaryTaiwan is attempting to implement the concept of a green economy through a Low Carbon Growth Plan (LCGP). However, the existing decision support tools for this measure have three key limitations: ignorance regarding the open economy; a lack of life cycle thinking; and limited categories of environmental impact. This study integrates environmentally extended, multi‐region input‐output analysis and hybrid life cycle assessment to quantify the potential environmental impact of the industrial activities and energy structure in Taiwan in 2020. Two novel indicators, environmental debts and loans, are also applied to identify the geographical shifting effects and tie environmental responsibility to the discussion.The results of this study reveal that under the existing LCGP, relative decoupling will be attained, but no significant environmental cobenefits other than those affecting climate change can be gained. Moreover, the current emission pledges cannot be fulfilled. The presence of increased environmental debt ratios reveals the geographical shifting effect of the LCGP. The main driver of the expansion of the environmental footprint can be attributed to the export of electronic components and products, which are not included in the agenda of policy discussions. As a result, three crucial policies are suggested to modify the existing LCGP: the implementation of a higher energy efficiency improvement target; rethinking the constraints on the electronics industry; and the development of a mechanism to include environmental issues in free trade agreement negotiations. With these changes, the realization of the current emission pledge and a green economy could be possible.
Apathy is more severe in vascular than amnestic mild cognitive impairment in a community: The Kurihara Project
Authors: Nakamura Kei , Kasai Mari , Ouchi Yoshitaka , Nakatsuka Masahiro , Tanaka Naofumi , Kato Yuriko , Nakai Megumi , Meguro Kenichi 
Published: October 2013

Aim: The aim of this study was to estimate the prevalence of apathy, and to compare vascular mild cognitive impairment (vMCI), amnestic MCI (amMCI), and other type using Clinical Assessment for Spontaneity (CAS).Methods: Agreement to take part in the study was obtained from 590 community dwellers, aged ≥75 years living in Kurihara, Japan. Of the 590 subjects, 221 had a clinical dementia rating (CDR) of 0 (normal); 295 had CDR 0.5 (mild cognitive impairment; MCI); and 74 had CDR 1+ (dementia). The CDR 0.5 subjects were divided into three groups: 55 with vMCI (Erkinjuntti et al. criteria), 91 with amMCI and 149 with other type. To evaluate the various aspects of apathy, we used the three CAS subscales: clinical interview (CAS1), self‐evaluation (CAS2), and caregiver assessment (CAS3). Three analyses were then performed to determine: (i) the validity of CAS; (ii) the prevalence rate of apathy in CDR 0 versus CDR 0.5 versus CDR 1+; and (iii) the prevalence rate of apathy in normal versus vMCI versus amMCI versus other type.Results: CAS was validated with the Apathy Evaluation Scale. There were significant differences among the three CDR groups in CAS1, CAS2 and CAS3 (P < 0.001). The prevalence rate of apathy in each CAS in the CDR 1+ group was higher than the CDR 0.5 group, which was higher than the CDR 0 group. There was a significant difference in CAS3 score between the four groups (the normal and the three subgroups; P < 0.001). Apathy in vMCI was more severe than in the other three groups (P < 0.05) on CAS3 score.Conclusions: vMCI subjects have more severe apathy compared with amMCI subjects on caregiver assessment.
The role of alloantibodies against human platelet antigen‐15 in multiply platelet transfused patients
Authors: Matsuhashi Mika , Tsuno Nelson H. , Sone Shinji , Mishima Yuko , Nagura Yutaka , Watanabe‐Okochi Naoko , Ikeda Toshiyuki , Kashiwase Koichi , Fukuda Shinya , Iriyama Takayuki , Hyodo Hironobu , Yamashita Takahiro , Kamei Yoshimasa , Arai Shunya , Minami Mutsuhiko , Fujii Tomoyuku , Kurokawa Mineo , Tozuka Minoru , Takahashi Koki , Santoso Sentot 
Published: October 2013

BackgroundSeveral studies have documented the role of antibodies against human platelet (PLT) antigen (HPA)‐15 in alloimmune‐mediated thrombocytopenia including neonatal alloimmune thrombocytopenia, PLT transfusion refractoriness (PTR), and posttransfusion purpura in Caucasian persons. However, the relevance of anti‐HPA‐15 in PTR among the Japanese population is still unclear.Study Design and MethodsThe sera of 305 multiply PLT transfused (MPT) patients, previously investigated for the presence of human leukocyte antigen (HLA) and HPA antibodies by mixed passive hemagglutination, were reexamined for the presence of HPA‐15 alloantibodies, using the monoclonal antibody–specific immobilization of PLT antigens (MAIPA) technique.ResultsAmong the 305 MPT samples, antibodies against HPA‐15 alloantigen was detected in seven (2.3%), two (0.66%) being anti‐HPA‐15a and five (1.64%) being anti‐HPA‐15b. Additionally, one case of CD109 panreactive antibody was found (0.33%). Among them, one aplastic anemia patient with blood group O developed multispecific anti‐HLA and anti‐HPA‐15b alloantibody after MPTs. However, transfusion with HLA‐matched PLTs of blood group AB did not result in adequate PLT count increment. Analysis of the possible influence of immune anti‐A and anti‐B by the MAIPA assay resulted negative, indicating that anti‐HPA‐15b is responsible for the refractory state in this patient.ConclusionIn this study, we found alloimmunization against HPA‐15a and ‐15b in Japanese populations and demonstrated the relevance of these antibodies in a patient with PTR.