bluuebunny/crossref_metadata_2025_split huggingface dataset:
Клинико-анамнестические факторы риска развития преэклампсии
Authors: Космуратова Ш.Б. , Битемирова Ш.К. , Жакиева Ш.С. , Жылкайдар Г.М. , Кайсажанова Г.А. 
Published: July 2024

Актуальность: Преэклампсия является одной из важнейших проблем в современном акушерстве. Несмотря на большое число исследований, этиологические факторы преэклампсии остаются неизвестными. Основными факторами риска развития преэклампсии являются хронические заболевания почек (58,6%), сосудистая патология (51,7%), эндокринная патология (38,0%), метаболический синдром (24,0%), заболевания сердца (22,0%), заболевания желудочно-кишечного тракта (20,7%). Значительная частота данного осложнения диктует необходимость проведения активных профилактических и лечебных мер у пациенток, находящихся в группе риска по развитию преэклампсии.
Цель исследования – оценка риска развития преэклампсии на основании клинико-анамнестических факторов.
Материалы и методы: Проведено исследование методом «случай-контроль», в которое вошли 218 женщин (117 контролей и 101 случай). Проведен анализ клинико-анамнестических показателей и данных гинекологического осмотра. Для построения модели прогноза преэклампсия с расчетом риска использовался многофакторный анализ (логистическая регрессия).
Результаты: При анализе соматического и гинекологического анамнеза - по хроническим экстрагенитальным заболеваниям в I группе выявлены: пиелонефрит, миопии, во II группе миопия и мастопатия, пиелонефрит и хроническая артериальная гипертензия. Варикозное расширение вен нижних конечностей встречалось в I группе с частотой 6,9%, во II группе 4,3%, (p>0,05). Из гинекологических заболеваний чаще всего в обеих группах встречались эрозия шейки матки 5,9% и 15% случаях, а только в I группе кисты яичников и миома матки выявлялись в 1% случаев соответственно, во II группе синдром поликистозных яичников и полип эндометрия в 1% случаев (p<0,05).
Заключение: В результате оценки ассоциации анамнестических и клинических данных с риском развития преэклампсии статистически значимая связь была обнаружена в отношении возраста обследуемых и возраста менархе, систолического и диастолического артериального давления при поступлении.
Habilidades Investigativas en Estudiantes de Grado en Carreras Pedagógicas. Un Saber Necesario en la Sociedad Globalizada
Authors: Mena Gallardo Alisson Anahí , Celi Jaramillo Karina Alexandra , Landin Garcia Marilyn Elizabeth 
Published: July 2024

Las habilidades investigativas son un componente esencial de la formación de profesionales competentes en cualquier área, y en particular en la educación. En una sociedad globalizada, los educadores deben tener la capacidad de generar conocimientos adaptables a los cambios, para contribuir a la mejora de la calidad educativa. A través de estas habilidades, podrán desarrollar e implementar tácticas pedagógicas novedosas, adaptarse a los cambios en los contextos educativos y contribuir al desarrollo de la sociedad a largo plazo. Sin embargo, existe un vacío de conocimiento sobre las habilidades específicas de investigación que deben adquirir y mejorar los estudiantes. Mediante este estudio, se pretendió llenar ese vacío de conocimiento mediante la identificación de las habilidades clave de investigación necesaria para el desarrollo de la educación. Los objetivos planteados en la presente investigación, buscaron comprender el nivel de desarrollo de habilidades investigativas en los estudiantes de carreras pedagógicas, identificar los factores que influyen en su adquisición y evaluar el impacto de estas habilidades en su futura práctica profesional. Además, buscar los puntos fuertes y débiles, para proponer algunas estrategias y lograr de esta manera optimizar y fortalecer las habilidades investigativas de búsqueda de información en estudiantes de carreras pedagógicas. A través del proceso metodológico practicado, se recoge la opinión de los estudiantes de carreras pedagógicas de la Universidad Nacional de Loja, mediante la aplicación de un cuestionario basado en una escala Likert con cinco categorías, que abarcan opciones desde “nunca” hasta “siempre”. Este enfoque permite medir la frecuencia con la que los participantes aplican las habilidades de investigación en el contexto educativo, lo cual permite obtener datos significativos sobre la competencia digital de los participantes en sus actividades cotidianas. En cuanto a los resultados, a través de la investigación de campo planteada, se proporcionó una visión integral sobre el estado de las habilidades investigativas en estudiantes de carreras pedagógicas, en el que se concluye que existe la necesidad imperativa de buscar fortalecer las estrategias formativas que fomenten el desarrollo de habilidades investigativas. Estos hallazgos subrayaron la necesidad de enriquecer la formación pedagógica con un enfoque más proactivo hacia las habilidades investigativas, utilizando prácticas de investigación desde etapas tempranas, así como una actualización constante mediante programas académicos que apliquen y tengan diseñadas propuestas didácticas efectivas que utilicen herramientas apropiadas para el contexto de la sociedad globalizada.
Mapping the Imprints of Stellar and Active Galactic Nucleus Feedback in the Circumgalactic Medium with X-Ray Microcalorimeters
Authors: Schellenberger Gerrit , Bogdán Ákos , ZuHone John A. , Oppenheimer Benjamin D. , Truong Nhut , Khabibullin Ildar , Jennings Fred , Pillepich Annalisa , Burchett Joseph , Carr Christopher , Chakraborty Priyanka , Crain Robert , Forman William , Jones Christine , Kilbourne Caroline A. , Kraft Ralph P. , Markevitch Maxim , Nagai Daisuke , Nelson Dylan , Ogorzalek Anna , Randall Scott , Sarkar Arnab , Schaye Joop , Veilleux Sylvain , Vogelsberger Mark , Wang Q. Daniel , Zhuravleva Irina 
Published: July 2024

Abstract
The Astro2020 Decadal Survey has identified the mapping of the circumgalactic medium (CGM; the gaseous plasma around galaxies) as a key objective. We explore the prospects for characterizing the CGM in and around nearby galaxy halos with a future large-grasp X-ray microcalorimeter. We create realistic mock observations from hydrodynamical simulations (EAGLE, IllustrisTNG, and Simba) that demonstrate a wide range of potential measurements, which will address the open questions in galaxy formation and evolution. By including all background and foreground components in our mock observations, we show why it is impossible to perform these measurements with current instruments, such as X-ray CCDs, and why only microcalorimeters will allow us to distinguish the faint CGM emission from the bright Milky Way (MW) foreground emission lines. We find that individual halos of MW mass can, on average and depending on star formation rate, be traced out to large radii, around R
500, and for larger galaxies even out to R
200, using prominent emission lines, such as O vii, or O viii. Furthermore, we show that emission-line ratios for individual halos can reveal the radial temperature structure. Substructure measurements show that it will be possible to relate azimuthal variations to the feedback mode of the galaxy. We demonstrate the ability to construct temperature, velocity, and abundance ratio maps from spectral fitting for individual galaxy halos, which reveal rotation features, active galactic nucleus outbursts, and enrichment.
The Variation in the Galaxy-wide Initial Mass Function for Low-mass Stars: Modeling and Observational Insights
Authors: Yan Zhiqiang , Li Jiadong , Kroupa Pavel , Jerabkova Tereza , Gjergo Eda , Zhang Zhi-Yu 
Published: July 2024

Abstract
The stellar initial mass function (IMF) characterizes the mass distribution of newly formed stars in various cosmic environments, serving as a fundamental assumption in astrophysical research. Recent findings challenge the prevalent notion of a universal and static IMF, proposing instead that the IMF’s shape is contingent upon the star formation environment. In this study, we analyze the galaxy-wide variation in the IMF for low-mass stars in both dwarf and massive galaxies with diverse observational methods. Despite systematic discrepancies between different approaches, an IMF model with a metallicity-dependent slope for the low-mass stars aligns with the majority of observations, indicating a high degree of uniformity in the star formation processes across the Universe. We also emphasize the need for a more comprehensive understanding of the variation in the low-mass IMF, considering measurement biases and factors beyond metallicity.
A coupled cartographic approach between bioclimatology and vegetation formations of Mexico
Authors: Gopar-Merino Fernando , Velazquez Alejandro , González-Pérez Alejandro , del Río Sara , Mas Jean F. , Penas Ángel 
Published: July 2024

Aims: The task of classifying and naming Mexican vegetation types has been undertaken by previous botanists, ecologists, and mapping agencies. However, discrepancies remain due to the lack of criteria and joint efforts from a geographical and botanical perspective. We aim to unravel the complex interactions between climate and vegetation in Mexico using climatic data and advanced mapping techniques, display in maps the transition from land cover to vegetation maps and couple geobotanical and bioclimatological approaches to provide a sound, unified system for identifying Mexican bioclimatic physiognomic patterns. Methods: Bioclimatic mapping was developed from the Digital Climatic Atlas of Mexico data source. In addition, land cover and vegetation data were obtained from the National Institute of Statistics and Geography of Mexico regrouped as described by the Standardized Hierarchical Vegetation Classification. These data were analysed via standard map crossing technics using geographic information systems. Results and conclusions: The results revealed five ombrotypes and five thermotypes, leading to the identification of 13 different bioclimatic classes, which, when combined with physiognomic types, led us to recognize 11 forests, 3 shrublands and 3 herbaceous formations (at a scale of 1:4,000,000). The core outcome is a detailed bioclimatic/physiognomic vegetation map including forests, shrublands and areas dominated by Herbaceous/Non-Vascular formations. The map highlights the critical importance of harmonising methodologies to ensure comprehensive and accurate insights into Mexico’s bioclimatic diversity.
Taxonomic reference: Villaseñor et al. (2005).
Syntaxonomic reference: Velázquez et al. (2021).
Abbreviations: INEGI = Instituto Nacional de Estadística y Geografía; SECLAVEMEX = Standardized Hierarchical Vegetation Classification; WBCS = Worldwide Bioclimatic Classification System.
La tendresse pour l’infans dans l’adulte : question métapsychologique ou question posée à la métapsychologie ?
Authors: Chiantaretto Jean-François 
Published: July 2024

Cet article propose de reprendre la question de la tendresse : là où elle a commencé – avec Freud – et là où elle a re-commencé – avec le dialogue entre Freud et Ferenczi. Elle se pose entre eux deux, avec pour enjeu une métapsychologie intégrant, d’une part, les processus psychiques de l’analyste en séance et, d’autre part, le statut de l’infans dans l’adulte.
Tendresse et illusion au cœur de la relation clinique
Authors: Janssen Christophe 
Published: July 2024

L’auteur tente de penser l’articulation entre tendresse et illusion telle qu’elle se pose au sein de la relation clinique. Ces deux notions impliquent une prise en compte de la réalité externe et de ses conséquences sur la réalité intrapsychique tant du patient que du thérapeute. À travers l’exploration théorique de ces processus mais aussi d’une vignette clinique, l’auteur en arrive à penser que la tendresse constitue la matière même de l’illusion à la base du lien intersubjectif.
Tendresse et contre-transfert en psychanalyse d’enfant
Authors: Golse Bernard 
Published: July 2024

Après l’évocation d’un cas clinique interrogeant le rapport de l’analyste au corps de l’enfant, l’auteur rappelle la distinction entre l’être (préobjectal) et l’existence (objectale) avant de dialectiser les affects au regard de la théorie des pulsions (être) et les émotions au regard de la théorie des relations d’objet (existence). Une petite histoire des idées amène ensuite à l’émotionalisation des sensations décrite par G. Haag et donc à l’impact contre-transférentiel des émotions.
Déjouer l’impact de l’absence : deux dispositifs ressources pour la protection de l’enfant
Authors: Vamos Julianna , Hours Armelle 
Published: July 2024

C’est sur la notion de protection que les auteures proposent d’engager une réflexion à deux voix. Comment faire exister véritablement la dimension de la protection de l’enfant au sein des institutions de soin ? L’échange s’installe à partir de l’expérience clinique diversifiée de chacune des co-auteures, tant en pouponnière et en maternité que dans le champ de la protection de l’enfance . Les situations de trauma chez l’enfant, quel que soit son âge, sont toujours des situations à risque pour de multiples raisons. L’expérience de l’absence, exacerbée dans les situations d’abandon, est susceptible d’avoir des effets délétères sur la psyché. Quels dispositifs peuvent être mis en œuvre pour amorcer les processus de prévention/restauration/réparation, indispensables à la croissance et à la vitalité de l’enfant ? Dans un premier temps, les vertus d’un dispositif spécifique de prévention mis en place dans une maternité seront présentées dans les situations d’accouchement sous X. Ensuite, un dispositif groupal utilisant le conte sera exposé, séquences cliniques à l’appui, dans les situations de placement chez l’enfant, permettant d’organiser le processus de restauration dans ces contextes où les dommages psychiques sont déjà à l’œuvre. La tendresse, dans l’attitude et dans les modalités d’approche des soignants, prend tout son sens, tout autant pour la psyché que du côté de l’intersubjectivité. On peut l’observer dans le processus de création et de restauration des conditions de ces dispositifs, comme le montreront les exemples cliniques.
Métapsychologie du pacte d’alliance radical : le maillage des familles avec des organisations totalitaires
Authors: Benghozi Pierre 
Published: July 2024

Le processus fondateur d’une alliance à une organisation radicale, la mécanique de son engrenage et les échecs de tentatives de « déradicalisation » restent souvent énigmatiques. L’auteur émet l’hypothèse que le lien d’alliance radical, tel un couplage des familles d’origine de deux partenaires, a une fonction économique psychique de remaillage inter-contenants réciproque des liens de filiation et d’affiliation entre le contenant familial de l’adepte et celui de l’organisation radicale. À partir d’une expérience clinique dans des contextes géopolitiques et des dispositifs très différents, il décrit l’attaque de la filiation et la figure d’un néo-père mythique comme une caractéristique paradigmatique de l’architecture des liens structurant le maillage contenant de ces organisations groupales qu’il définit comme radicales et totalitaires. Il analyse le processus du pacte d’alliance radicale comme une néo-conversion à un néo-mythe d’auto-engendrement avec des néo-rituels à partir de la rencontre entre une demande, en résonance à une vulnérabilité, et une offre d’une organisation prédatrice totalitaire.
Comparing Sleep Quality, Duration, and Efficiency Among Low-Income Community-Dwelling Older Adults With and Without Physical Disabilities
Authors: Brightman James D. , Lafontant Kworweinski , Suarez Jethro Raphael M. , Crook Jennifer M. , Thiamwong Ladda 
Published: July 2024

Purpose:

Physical disabilities may exacerbate the natural decline in sleep quality that occurs with aging. In the current study, we assessed sleep quality and medicinal sleep aid use among 87 community-dwelling older adults with (
n
= 24) and without (
n
= 63) physical disabilities.

Method:
Sleep quality, duration, and efficiency were assessed subjectively with the Pittsburgh Sleep Quality Index. Sleep duration and efficiency were objectively measured with actigraphy. Participants self-reported medicinal sleep aid use.

Results:

Significant group differences were observed in sleep duration measured objectively (
p
= 0.01) and subjectively (
p
= 0.04). No other group differences were observed for sleep factors (
p
> 0.05) or medicinal sleep aid use (
p
= 0.41).

Conclusion:

Findings show that physical disability may be a factor in sleep duration; however, physical disability was not found to be associated with worsened sleep perception or greater reliance on medicinal sleep aids. Future research should consider longer objective actigraphy assessment windows and explore potential subgroup differences in sex and race/ethnicity. [
Journal of Gerontological Nursing, 50
(7), 12–18.]
A perseguição legal à homossexualidade na Península Ibérica: séculos XIX e XX
Authors: Afonso Raquel 
Published: July 2024

O quadro legal que serve de base à perseguição da homossexualidade em Portugal e no Estado espanhol surge antes do início das ditaduras ibéricas. Em Portugal, por exemplo, a I República cria legislação contra “os que praticam vícios contra a natureza”, a partir da Lei da Mendicidade (1912). No caso espanhol, o Código Penal de 1870 introduz, pela primeira vez, as categorias de delitos sexuais, que são usados para a detenção de homossexuais até à chegada da democracia. Apesar da homo/lesbofobia ser anterior aos regimes fascistas, é neste tipo de regimes que a perseguição da homossexualidade se transforma num elemento chave. Estas e outras leis, a aplicar mais tarde pelo Estado Novo e pelo franquismo, levam a que a homossexualidade seja observada enquanto crime. As comparações efetuadas pretendem reforçar a necessidade de continuar a resgatar a memória LGBTI, em particular na Península Ibérica. Assim, este artigo pretende analisar e comparar a legislação aplicada a homossexuais nos dois países, desde o século XIX, com o surgimento dos primeiros Códigos Penais, até à descriminalização da homossexualidade, que tem lugar em meados dos anos 80 do século XX.
Dexmedetomidine vs. Propofol: Haemodynamic Changes in Conscious Sedation in Arthroscopic Shoulder Surgery in the Beach Chair Position: A Randomized Control Trial
Authors: Hapugoda Minura , Kariyawasam Lewan P. 
Published: July 2024

Background: Interscalene brachial plexus block (ISB) combined with conscious sedation is a viable alternative to general anaesthesia for arthroscopic shoulder surgery in the beach chair position. The purpose of the trial was to compare the haemodynamic instability and safety of Dexmedetomidine vs Propofol for conscious sedation in arthroscopic shoulder surgery in the beach chair position. Method: A single-blinded prospective randomized trial was conducted in 56 patients randomly allocated into Dexmedetomidine and Propofol groups for conscious sedation following ISB placement. The primary outcome was to measure intraoperative haemodynamic variations (systolic blood pressure, mean arterial pressure, heart rate) in the two groups maintaining adequate conscious sedation during arthroscopic shoulder surgery in the beach chair position. Results: In the dexmedetomidine group a significantly higher percentage of systolic blood pressure (21.86 𝑣𝑠 10.81%, p = 0.001, 𝑑 = 1.05) and a higher percentage heart rate (18.52 vs 9.02%, p = 0.002, 𝑑 = .98) drop from baseline measurements was noted. A large (d ≥ 0.8) Cohen’s effect size suggested the high practical significance of the finding. Perioperative hypotensive (f=19, p<0.001) and bradycardic (f=21, p=0.003) episodes were significantly more frequent in the dexmedetomidine group. The propofol group had a greater incidence of airway complications requiring intervention (f=6 vs f=0, p=.023). Conclusion: Dexmedetomidine leads to significant blood pressure and heart rate reductions from baseline values in the beach chair position providing controlled hypotension and has minimal airway complications in patients undergoing arthroscopic shoulder surgery in the beach chair position under ISB and conscious sedation compared to Propofol.
Health-related quality of life in children with severe hemophilia A on emicizumab prophylaxis
Authors: Hassan Ahmed S. , Sherief Laila M. , Hamdy Mona , Abbas Ahmed M. , Elagamy Osama 
Published: July 2024

Background
Emicizumab is a novel nonreplacement therapy for patients with hemophilia A. It is intended to reduce the frequency and severity of serious bleeding episodes in patients with hemophilia A.

Aim
To assess how emicizumab affected quality of life and physical activity in children with severe hemophilia A.

Patients and methods
Thirty-seven children with severe hemophilia A received emicizumab prophylaxis. We used EQ-5D-Y and pedHAL activity list questionnaires to assess quality of life and physical activity, respectively, at baseline (before receiving emicizumab prophylaxis) and after 1 year of regular emicizumab prophylaxis.

Results
The mean age of the children included in the study was 9.32 ± 3.75 years. Of them, 19 patients were with FVIII inhibitors (51.35%), and 18 patients were negative for FVIII inhibitors (48.65%). The median (interquartile range) PedHAL sum score was 57.6 (48.8–62) at baseline, then reached 76 (70–81.5) after a year of emicizumab prophylaxis; this change was found to be statistically significant (P<0.001). Also, there was a significant increase in the proportion of patients with no problem in all EQ-5d-Y dimensions after a year of emicizumab prophylaxis (P<0.05). The median (interquartile range) value of the visual analog scale score at baseline was 67 (54–75) and became 76 (70–81.5) after a year of receiving emicizumab prophylaxis. This improvement was statistically significant (P<0.001).

Conclusion
Emicizumab prophylaxis improves quality of life and physical activity in children with severe hemophilia A.
Prognostic impact of inhibitors of DNA binding proteins1 and inhibitors of DNA binding proteins4 genes expression on adult Egyptian patients with acute myeloid leukemia
Authors: Abdelrahman Amira M. N. , Zidan Magda A. E.-A. M. , Abdellateif Mona S. , Awad Ola S. E. D. , Hassan Naglaa M. 
Published: July 2024

Background
Acute myeloid leukemia (AML) pathogenesis and treatment are currently being better understood at an accelerated rate. Determining genetic and epigenetic changes that can identify patients who are at risk of poor outcomes is therefore desired to optimize treatment options. Many solid tumors have been reported to overexpress Inhibitors of DNA binding proteins (ID1), but few research has looked at the clinical significance of ID1 expression in AML. Additionally, little research has been focused on the direct role of ID4 in myeloid malignancies, as well as its expression and methylation patterns. The aim of the current study was to assess ID1 and ID4 gene expression in bone marrow (BM) aspiration specimens of 91 AML patients, compared with 14 control donors of bone marrow transplantation (BMT), using real-time polymerase chain reaction (RT-PCR). Data were correlated with patients’ clinicopathological features, response to treatment, disease-free survival (DFS), and overall survival (OS) rates.

Results
ID1 transcript level was significantly increased in AML bone marrow samples compared with normal controls (P = 0.002), while ID4 gene expression showed a nonsignificant difference (P = 0.717). In addition, there was a significant increase in ID1 gene expression in fms-like tyrosine kinase 3 (FLT3) mutant group than fms-like tyrosine kinase 3 wild group (P = 0.010). The total leukocytic count (TLC) was significantly higher in patients with high ID1 expression (P = 0.038) and patients with undetected ID4 expression (P = 0.025). No significant associations were detected between ID1 and ID4 expression levels and patients’ clinicopathological characteristics and OS rates.

Conclusion
In contrast to ID4, overexpressed ID1 can be adopted as a genetic biomarker for diagnosing AML. ID1 and ID4 expressions did not affect the patients’ OS or DFS.