bluuebunny/crossref_metadata_2025_split huggingface dataset:
Characterization of in vitro metabolites of cudratricusxanthone A in human liver microsomes
Authors: Sim Juhee , Choi Eunhwa , Jeong Gil‐Saeng , Lee Sangkyu 
Published: March 2015

AbstractCudratricusxanthone A (CTXA), isolated from the roots of Cudrania tricuspidata, exhibits several biological activities; however, metabolic biotransformation was not investigated. Therefore, metabolites of CTXA were investigated and the major metabolic enzymes engaged in human liver microsomes (HLMs) were characterized using liquid chromatography‐tandem mass spectrometry (LC‐MS/MS). CTXA was incubated with HLMs or human recombinant CYPs and UGTs, and analysed by an LC‐MS/MS equipped electrospray ionization (ESI) to qualify and quantify its metabolites. In total, eight metabolites were identified: M1–M4 were identified as mono‐hydroxylated metabolites during Phase I, and M5–M8 were identified as O‐glucuronidated metabolites during Phase II in HLMs. Moreover, these metabolite structures and a metabolic pathway were identified by elucidation of MSn fragments and formation by human recombinant enzymes. M1 was formed by CYP2D6, and M2–M4 were generated by CYP1A2 and CYP3A4. M5–M8 were mainly formed by UGT1A1, respectively. While investigating the biotransformation of CTXA, eight metabolites of CTXA were identified by CYPs and UGTs; these data will be valuable for understanding the in vivo metabolism of CTXA. Copyright © 2015 John Wiley & Sons, Ltd.
Patterns of gray matter atrophy in atypical parkinsonism syndromes: a VBM meta‐analysis
Authors: Yu Fang , Barron Daniel S. , Tantiwongkosi Bundhit , Fox Peter 
Published: March 2015

AbstractBackground and PurposeAccurate diagnosis of Atypical Parkinsonian Syndromes (APS) is important due to differences in prognosis and management, but remains a challenge in the clinical setting. The purpose of our meta‐analysis was to identify characteristic patterns of gray matter atrophy in Corticobasal Degeneration (CBD), Progressive Supranuclear Palsy (PSP), Multisystem‐Atrophy Parkinsonian type (MSA‐P), and Idiopathic Parkinson's Disease (IPD).Materials and MethodsWhole‐brain meta‐analysis was performed on 39 published voxel‐based morphometry (VBM) articles (consisting of 404 IPD, 87 MSA‐P, 165 CBD, and 176 PSP subjects) using the modified Anatomic Likelihood Estimation method. Based on these results, contrast analyses were then utilized to determine areas of atrophy shared by as well as unique to each disorder.ResultsCBD was characterized by asymmetric gray matter atrophy in multiple cortical regions, while the thalamus‐midbrain and insula were predominantly involved in PSP. The striatum and superior cerebellum were affected in MSA‐P, while IPD demonstrated an anterior cerebral pattern. Although there was a mild overlap among PSP, CBD, and MSA‐P, significant regions of atrophy unique to each disorder were identified, including (1) the superior parietal lobule in CBD (2) putamen in MSA‐P (3) insula and medial dorsal nucleus in PSP.ConclusionOur results suggest that there are characteristic patterns of atrophy in APS. Guided by these findings, future studies on the individual subject level may lead to the development of robust imaging biomarkers.
A Mutasynthesis Approach with a Penicillium chrysogenum ΔroqA Strain Yields New Roquefortine D Analogues
Authors: Ouchaou Kahina , Maire Florian , Salo Oleksandr , Ali Hazrat , Hankemeier Thomas , van der Marel Gijsbert A. , Filippov Dmitri V. , Bovenberg Roel A. L. , Vreeken Rob J. , Driessen Arnold J. M. , Overkleeft Herman S. 
Published: March 2015

AbstractPenicillium chrysogenum, which lacks the roqA gene, processes synthetic, exogenously added histidyltryptophanyldiketopiperazine (HTD) to yield a set of roquefortine‐based secondary metabolites also produced by the wild‐type strain. Feeding a number of synthetic HTD analogues to the ΔroqA strain gives rise to the biosynthesis of a number of new roquefortine D derivatives, depending on the nature of the synthetic HTD added. Besides delivering semisynthetic roquefortine analogues, the mutasynthesis studies presented here also shed light on the substrate preferences and molecular mechanisms employed by the roquefortine C/D biosynthesis gene cluster, knowledge that may be tapped for the future development of more complex semisynthetic roquefortine‐based secondary metabolites.
Biological characteristics of adipose tissue‐derived stem cells labeled with amine‐surface‐modified superparamagnetic iron oxide nanoparticles
Authors: Wang Nan , Zhao Jing‐Yuan , Guan Xin , Dong Yue , Liu Yang , Zhou Xiang , Wu Ren'an , Du Yue , Zhao Liang , Zou Wei , Han Chao , Song Lin , Sun Bo , Liu Yan , Liu Jing 
Published: March 2015

AbstractCell labeling and tracking are becoming increasingly important areas within the field of stem cell transplantation. The ability to track the migration and distribution of implanted cells is critical to understanding the beneficial effects and mechanisms of stem cell therapy. The present study investigated the effects of amine‐surface‐modified superparamagnetic iron oxide (SPIO) nanoparticles on the biological properties of human adipose tissue‐derived stem cells (hADSCs). Monodisperse hydrophobic magnetite (Fe3O4) nanoparticles were prepared using silicon and surface‐modified with amine coating. Cell viability, proliferation, differentiation potential, and surface marker expression were evaluated. The magnetic particles (10–18 nm) displayed high labeling efficiency and stability in hADSCs. SPIO‐labeled cells produced a hypointense signal and were effectively visualized by MRI for up to 21 days. The results of MTT proliferation assays and flow cytometry analysis demonstrated that SPIOs were biocompatible, viz. the labeling process did not cause cell death or apoptosis and had no side effects on cell proliferation. In vivo experiments showed that the magnetic particles did not affect liver and kidney function. The successful and stable labeling of hADSCs combined with efficient magnetic tropism demonstrates that SPIOs are promising candidates for hADSC tracking in hADSC‐based cell therapy applications.
Identification of LncRNAs/mRNAs related to endometrium function regulated by Homeobox A10 in Ishikawa cells
Authors: Lin Ruiyi , Zhao Changzhi , Jing Lu , Zhao Shuhong 
Published: March 2015

AbstractAs a well‐known transcription factor, Homeobox A10 (HOXA10) regulates a large number of downstream target genes, leading to the proper function development of endometrium for embryo implantation. The change of HOXA10 gene expression level can alter the expressions of many other genes, including coding and noncoding transcripts. In our study, mRNA and LncRNA expression profiles screening was performed by microarray when the HOXA10 gene expression level increased in Ishikawa cells. A total of 907 mRNAs and 1,026 LncRNAs were identified as differentially expressed transcripts (Fold Change ≥2, P‐value <0.05, and Q‐value <0.05) between HOXA10 overexpressed and control Ishikawa cells. Further analysis identified that these mRNAs participated in various biological processes, such as blood vessel development, cell adhesion, cell cycle, etc. Also, 14 enhancer‐like LncRNAs and 108 LincRNAs with their nearby mRNAs were identified as coregulated transcripts. Our results showed that the mRNA and LncRNA expression profiles differed significantly between the two groups and provided useful information for further studying the molecular mechanisms of HOXA10 in endometrium.
Multiscale Discrete Supercomputing – A Game Changer for Process Simulation?
Authors: Ge Wei , Lu Liqiang , Liu Shiwen , Xu Ji , Chen Feiguo , Li Jinghai 
Published: March 2015

AbstractTo address the challenge of virtual process engineering (VPE), a systematic co‐design of the physical model, numerical software, and computer hardware was conducted, eventually leading to the so‐called EMMS Paradigm, which can greatly accelerate simulation speed while reducing its cost. Following this paradigm, a multiscale software framework was developed, coupling continuum and coarse‐grained discrete simulations and a multiscale hardware architecture with different parallelization schemes, which have drawn the dream of VPE a substantial step closer: High‐resolution interactive simulation of pilot‐scale reactors or direct numerical simulation of microreactors, both at quasi‐real time speed for the multiphase hydrodynamics, are now possible on the upgraded Mole‐8.5 supercomputing system. The spectrum of multiscale methods available or to be developed for different purposes in VPE, and the corresponding software and hardware co‐designing from more fundamental levels, are discussed also.
Unprecedented Trinuclear AgI Complex with 2,4,6‐Tris(2‐pyrimidyl)‐1,3,5‐triazine as an Efficient Catalyst for the Aziridination of Olefins
Authors: Safin Damir A. , Pialat Amélie , Korobkov Ilia , Murugesu Muralee 
Published: March 2015

AbstractAn unprecedented trinuclear heteroleptic AgI complex was isolated using a stable multidentate 2,4,6‐tris(2‐pyrimidyl)‐1,3,5‐triazine (TPymT) ligand. The obtained compound is an efficient catalyst for the direct aziridination of terminal olefins.
Homo‐ and Heteronuclear Compounds with a Symmetrical Bis‐hydrazone Ligand: Synthesis, Structural Studies, and Luminescent Properties
Authors: Rodríguez‐Hermida Sabina , Lago Ana B. , Carballo Rosa , Fabelo Oscar , Vázquez‐López Ezequiel M. 
Published: March 2015

AbstractNine new coordination compounds have been synthesized by the reaction of salts of bivalent metal ions (a=ZnII, b=CuII, c=NiII, d=CoII) with the bis(benzoylhydrazone) derivative of 4,6‐diacetylresorcinol (H4L). Three kinds of complexes have been obtained: homodinuclear compounds [M2(H2L)2]⋅nH2O (1 a, 1 b, 1 c, and 1 d), homotetranuclear compounds [M4(L)2]⋅n(solv) (2 a and 2 c), and heterotetranuclear compounds [Zn2M2(L)2]⋅n(solv) (2 ab, 2 ac, and 2 ad). The structures of the free ligand H4L⋅2 DMSO and its complexes [Zn2(H2L)2(DMSO)2] (1 a*), [Zn4(L)2(DMSO)6] (2 a*), and [Zn0.45Cu3.55(L)2(DMSO)6]⋅2 DMSO (2 ab*) were elucidated by single‐crystal X‐ray diffraction. The ligand shows luminescence properties and its fluorimetric behavior towards MII metals (M=Zn, Cu, Ni and Co) has been studied. Furthermore, the solid‐state luminescence properties of the ligand and compounds have been determined at room temperature. 1H NMR spectroscopic monitoring of the reaction of H4L with ZnII showed the deprotonation sequence of the OH/NH groups upon metal coordination. Heteronuclear reactions have also been monitored by using ESI‐MS and spectrofluorimetric techniques.
Synthesis of 3,8‐Dichloro‐6‐ethyl‐1,2,5,7‐tetramethyl–BODIPY from an Asymmetric Dipyrroketone and Reactivity Studies at the 3,5,8‐Positions
Authors: Zhao Ning , Vicente M. Graça H. , Fronczek Frank R. , Smith Kevin M. 
Published: March 2015

AbstractThe asymmetric BODIPY 1 a (BODIPY=4,4‐difluoro‐4‐bora‐3a,4a‐diaza‐s‐indacene), containing two chloro substituents at the 3,8‐positions and a reactive 5‐methyl group, was synthesized from the asymmetric dipyrroketone 3, which was readily obtained from available pyrrole 2 a. The reactivity of 3,8‐dichloro‐6‐ethyl‐1,2,5,7‐tetramethyl‐BODIPY 1 a was investigated by using four types of reactions. This versatile BODIPY undergoes regioselective Pd0‐catalyzed Stille coupling reactions and/or regioselective nucleophilic addition/elimination reactions, first at the 8‐chloro and then at the 3‐chloro group, using a variety of organostannanes and N‐, O‐, and S‐centered nucleophiles. On the other hand, the more reactive 5‐methyl group undergoes regioselective Knoevenagel condensation with an aryl aldehyde to produce a monostyryl‐BODIPY, and oxidation with 2,3‐dichloro‐5,6‐dicyano‐1,4‐benzoquinone (DDQ) gives the corresponding 5‐formyl‐BODIPY. Investigation of the reactivity of asymmetric BODIPY 1 a led to the preparation of a variety of functionalized BODIPYs with λmax of absorption and emission in the ranges 487–587 and 521–617 nm, respectively. The longest absorbing/emitting compound was the monostyryl‐BODIPY 16, and the largest Stokes shift (49 nm) and fluorescence quantum yield (0.94) were measured for 5‐thienyl‐8‐phenoxy‐BODIPY 15. The structural properties (including 16 X‐ray structures) of the new series of BODIPYs were investigated.
Cyclic isoDGR and RGD Peptidomimetics Containing Bifunctional Diketopiperazine Scaffolds are Integrin Antagonists
Authors: Panzeri Silvia , Zanella Simone , Arosio Daniela , Vahdati Leila , Dal Corso Alberto , Pignataro Luca , Paolillo Mayra , Schinelli Sergio , Belvisi Laura , Gennari Cesare , Piarulli Umberto 
Published: March 2015

AbstractThe cyclo[DKP‐isoDGR] peptidomimetics 2–5, containing bifunctional diketopiperazine (DKP) scaffolds that differ in the configuration of the two DKP stereocenters and in the substitution at the DKP nitrogen atoms, were prepared and examined in vitro in competitive binding assays with purified αvβ3 and αvβ5 integrin receptors. IC50 values ranged from low nanomolar (ligand 3) to submicromolar with αvβ3 integrin. The biological activities of ligands cyclo[DKP3‐RGD] 1 and cyclo[DKP3‐isoDGR] 3, bearing the same bifunctional DKP scaffold and showing similar αVβ3 integrin binding values, were compared in terms of their cellular effects in human U373 glioblastoma cells. Compounds 1 and 3 displayed overlapping inhibitory effects on the FAK/Akt integrin activated transduction pathway and on integrin‐mediated cell infiltration processes, and qualify therefore, despite the different RGD and isoDGR sequences, as integrin antagonists. Both compounds induced apoptosis in glioma cells after 72 hour treatment.
Vinylation of Aldehydes Using Mn/Cr Alloy and a N4‐Ligand/NiII‐Catalyst
Authors: Harnying Wacharee , Berkessel Albrecht 
Published: March 2015

AbstractWe report an efficient and practical protocol for the Cr/Ni‐catalyzed vinylation of aldehydes, based on the use of Mn/Cr alloy (ca. 10 % Cr) and TMSCl. No additional Cr salts need to be added. In the presence of NiCl2 (0.3 mol %) and a bis(ketimino)‐2,2′‐bipyridine as N4‐chelating ligand (1 mol %), the vinylations proceed smoothly at room temperature. The presence of catalytic amounts of MeOH and LiOAc as additives was found to further promote the efficiency of the catalytic system, even in the absence of the ligand. Detailed reaction monitoring revealed that LiOAc accelerates the product alcohol silylation, thus increasing the turnover rate.
Stereoselective Peterson Olefinations from Bench‐Stable Reagents and N‐Phenyl Imines
Authors: Das Manas , Manvar Atul , Jacolot Maïwenn , Blangetti Marco , Jones Roderick C. , O'Shea Donal F. 
Published: March 2015

AbstractThe synthesis of bench‐stable α,α‐bis(trimethylsilyl)toluenes and tris(trimethylsilyl)methane is described and their use in stereoselective Peterson olefinations has been achieved with a wide substrate scope. Product stereoselectivity was poor with carbonyl electrophiles (E/Z ∼1:1 to 4:1) though this was significantly improved by employing the corresponding substituted N‐benzylideneaniline (up to 99:1) as an alternative electrophile. The olefination byproduct was identified as N,N‐bis(trimethylsilyl)aniline and could be easily separated from product by aqueous acid extraction. Evidence for an autocatalytic cycle has been obtained.
Tunable Porosities and Shapes of Fullerene‐Like Spheres
Authors: Dielmann Fabian , Fleischmann Matthias , Heindl Claudia , Peresypkina Eugenia V. , Virovets Alexander V. , Gschwind Ruth M. , Scheer Manfred 
Published: March 2015

AbstractThe formation of reversible switchable nanostructures monitored by solution and solid‐state methods is still a challenge in supramolecular chemistry. By a comprehensive solid state and solution study we demonstrate the potential of the fivefold symmetrical building block of pentaphosphaferrocene in combination with CuI halides to switch between spheres of different porosity and shape. With increasing amount of CuX, the structures of the formed supramolecules change from incomplete to complete spherically shaped fullerene‐like assemblies possessing an Ih‐C80 topology at one side and to a tetrahedral‐structured aggregate at the other. In the solid state, the formed nano‐sized aggregates reach an outer diameter of 3.14 and 3.56 nm, respectively. This feature is used to reversibly encapsulate and release guest molecules in solution.
ChemInform Abstract: Low‐Temperature Topochemical Transformation of Bi13Pt3I7 into the New Layered Honeycomb Metal Bi12Pt3I5.
Authors: Kaiser Martin , Rasche Bertold , Isaeva Anna , Ruck Michael 
Published: March 2015

AbstractSingle crystals of Bi13Pt3I7 (prepared from a mixture of H2 treated Bi, Pt, and BiI3 at 380 °C for 6 d).
ChemInform Abstract: BaFAlSi and BaFAlGe: First Transition Metal‐Free LaOAgS‐Type Fluoride Tetrelides.
Authors: Charkin Dmitri O. , Plokhikh Igor V. , Kuznetsov Alexey N. , Kazakov Sergey M. 
Published: March 2015

AbstractBaFAlSi (I) and BaFAlGe (II) are obtained from attempts to prepare a series of new representatives of Al and Ga tretrelides with the “1111” LaOAgS structure.
ChemInform Abstract: A Study on Photoluminescence and Energy Transfer of SrAlSi4N7:Eu2+, Ce3+ Phosphors for Application in White‐Light LED.
Authors: Chen Lei , Liu Ronghui , Zhuang Weidong , Liu Yuanhong , Hu Yunsheng , Zhou Xiaofang , Ma Xiaole 
Published: March 2015

AbstractA series of Ce3+ and Eu2+ co‐activated SrAlSi4N7 phosphors is prepared by solid‐state reaction of stoichiometric amounts of Sr3N2, AlN, Si3N4, EuN, and CeN (Mo crucible, 1650 °C, 8 h, 5% H2/N2).
ChemInform Abstract: Increasing the Thermoelectric Figure of Merit of Tetrahedrites by Co‐Doping with Nickel and Zinc.
Authors: Lu Xu , Morelli Donald T. , Xia Yi , Ozolins Vidvuds 
Published: March 2015

AbstractCu10.5Ni1.5‐xZnxSb4S13 is prepared by melting of the elements (evacuated quartz tubes, 923 K, 12 h; cooling to 273 K with a rate of 0.4 K/min).
ChemInform Abstract: Experimental Investigation of Phase Equilibria in the Co—Hf System.
Authors: Lu Xingxu , Cheng Kaiming , Liu Shuhong , Li Kai , Zheng Feng , Du Yong 
Published: March 2015

AbstractPhase equilibria in the Co‐Hf binary system are investigated by XRD, TEM, SEM, electron probe microanalysis, and DSC on annealed and as‐cast alloys.
ChemInform Abstract: O‐Monoacyltartaric Acid Catalyzed Enantioselective Conjugate Addition of a Boronic Acid to Dienones: Application to the Synthesis of Optically Active Cyclopentenones.
Authors: Sugiura Masaharu , Kinoshita Ryo , Nakajima Makoto 
Published: March 2015

AbstractThe enantioselective addition of styrylboronic acid (II) to symmetrical and unsymmetrical dienones, catalyzed by O‐monoacyltartaric acid, affords monostyrylated adducts [ct.
ChemInform Abstract: Palladium‐Catalyzed Decarboxylative Generation and Asymmetric Allylation of α‐Imino Anions
Authors: Qian Xiaoyan , Ji Pengfei , He Chang , Zirimwabagabo Jean‐Olivier , Archibald Michelle M. , Yeagley Andrew A. , Chruma Jason J. 
Published: March 2015

Abstractusing (S,S)‐f‐binaphane (BPF) as chiral catalyst ligand
ChemInform Abstract: Stereoselective Synthesis of (E)‐3,3‐Diaryl and (E)‐3‐Aryl‐3‐aryloxy Allylamines and Allylalcohols from trans‐Cinnamyl Chloride and Alcohol.
Authors: Limberger Jones , Claudino Thiago S. , Monteiro Adriano L. 
Published: March 2015

AbstractVinyl bromides (I) are used as substrates in cross‐coupling reactions furnishing arylated products (III) and (V) in good to excellent yields and complete retention of the (E)‐configuration.
ChemInform Abstract: Efficient Mukaiyama Aldol Reaction in Water with TiO4 Tetrahedra on a Hydrophobic Mesoporous Silica Surface.
Authors: Shintaku Hiroshi , Nakajima Kiyotaka , Kitano Masaaki , Hara Michikazu 
Published: March 2015

AbstractTiO4 deposited onto 1H,1H,2H,2H‐tridecafluorooctyl‐modified mesoporous silica (TFS) shows the best results in the surfactant‐free aqueous Mukaiyama reaction of benzaldehyde and 1‐(trimethylsilyloxy)cyclohexene of the tested catalysts.
ChemInform Abstract: Silver‐Catalyzed Transformation of Propargylic Amine N‐Oxides to Enones and Acyloxy Ketones via Isoxazolinium Intermediates.
Authors: Cui Jian‐Fang , Kung Karen Ka‐Yan , Ko Hok‐Ming , Hui Tsz‐Wai , Wong Man‐Kin 
Published: March 2015

AbstractThe propargylic amine N‐oxides are formed in situ by oxygenation of the corresponding propargyl amines.
ChemInform Abstract: Iodo Meyer—Schuster Rearrangement of 3‐Alkoxy‐2‐yn‐1‐ols for β‐Mono (Exclusively Z‐Selective)‐/Disubstituted α‐Iodo‐α,β‐Unsaturated Esters.
Authors: Puri Surendra , Thirupathi Nuligonda , Sridhar Reddy Maddi 
Published: March 2015

AbstractAn efficient synthesis of linear α‐iodo‐α,β‐unsaturated esters from readily accessible propargylic alcohols is described.
ChemInform Abstract: Direct Synthesis of Allylic Thioethers under Greener Conditions: A Solvent‐ and Catalyst‐Free Approach.
Authors: Tabarelli Greice , Godoi Marcelo , Canto Romulo F. S. , Mora Jose R. , Nome Faruk , Braga Antonio L. 
Published: March 2015

AbstractA new, environmentally friendly approach for the synthesis of different allylic thioethers (III) directly from allylic alcohols and thiols is developed.
ChemInform Abstract: Phase‐Transfer Catalysis in Oxidations Based on the Covalent Bonding of Hydrogen Peroxide to Amphiphilic Flavinium Salts.
Authors: Zelenka Jan , Hartman Tomas , Klimova Katerina , Hampl Frantisek , Cibulka Radek 
Published: March 2015

AbstractSulfoxides (II) are synthesized by two‐phase oxidation of sulfides (I) with hydrogen peroxide using a bridged flavinium salt as catalyst.
ChemInform Abstract: The Palladium(II) Complex of N,N‐Diethyl‐1‐ferrocenyl‐3‐thiabutanamine: Synthesis, Solution and Solid State Structure and Catalytic Activity in Suzuki—Miyaura Reaction.
Authors: Damljanovic Ivan , Stevanovic Dragana , Pejovic Anka , Ilic Danijela , Zivkovic Marija , Jovanovic Jovana , Vukicevic Mirjana , Bogdanovic Goran A. , Radulovic Niko S. , Vukicevic Rastko D. 
Published: March 2015

AbstractThe title complex generated in situ is an excellent catalyst in Suzuki—Miyaura coupling.
ChemInform Abstract: LiAlH4‐Promoted Tandem Reduction/Oxidation of Fluorenyl Derivatives under Air.
Authors: Matviiuk Tetiana , Menendez Christophe , Carayon Chantal , Saffon Nathalie , Voitenko Zoia , Lherbet Christian , Baltas Michel 
Published: March 2015

AbstractSince a 9‐hydroxyfluorenyl derivative such as (II) is observed as by‐product in the reduction of a pyrrolidine‐2,5‐dione such as (I), the process is investigated in detail.
ChemInform Abstract: Iodine‐Promoted Sequential C(sp3)—H Functionalization Reactions: An Annulation Strategy for the Construction of 3‐Methylthio‐4‐arylmaleimides.
Authors: Gao Qinghe , Wu Xia , Li Yuhong , Liu Shan , Meng Xianggao , Wu Anxin 
Published: March 2015

AbstractMethylthio‐substituted maleimides are synthesized by a novel annulation strategy from methyl ketones, actetamides, and DMSO in the presence of I2 via an iodination/Kornblum oxidation/amidation/cyclization sequence.
ChemInform Abstract: α,α‐Dichlorination of Oxindole Derivatives Using (Dichloroiodo)benzene.
Authors: Murphy Graham K. , Abbas Farhana Z. , Poulton Amy V. 
Published: March 2015

Abstract3‐Diazo‐2‐oxindoles (I) and (III), synthesized from isatins, are rapidly and chemoselectively dichlorinated with PhICl2 in the presence of pyridine under mild conditions in good to excellent yields.
ChemInform Abstract: Friedel—Crafts Alkylation of Indoles Exclusively in Water Catalyzed by Ionic Liquid Supported on a Polyacrylonitrile Fiber: A Simple “Release and Catch” Catalyst.
Authors: Shi Xian‐Lei , Lin Huikun , Li Pengyu , Zhang Wenqin 
Published: March 2015

AbstractTitle reaction synthesizes bis(indolyl)methanes under mild and environmentally friendly conditions in high yields.
ChemInform Abstract: Tandem Insertion—Cyclization Reaction of Isocyanides in the Synthesis of 1,4‐Diaryl‐1H‐imidazoles: Presence of N‐Arylformimidate Intermediate.
Authors: Pooi Benjamin , Lee Jeongbin , Choi Kyujin , Hirao Hajime , Hong Soon Hyeok 
Published: March 2015

AbstractBenzyl isocyanides and the activated methylene analogue (IX) can be used as starting materials in the reaction with aryl isocyanides.