bluuebunny/crossref_metadata_2025_split huggingface dataset:
Transfer of Sulfur: From Simple to Diverse
Authors: Liu Hui , Jiang Xuefeng 
Published: July 2013

AbstractThe introduction of sulfur atoms onto target molecules is an important area in organic synthesis, in particular in the synthesis of pharmaceutical compounds, and a wide variety of sulfuration agents have been developed for thionation reactions over the past few decades. In this Focus Review, we collect and summarize the CS bond‐formation reactions that have been used to construct CS bonds in natural products and pharmaceutical compounds.
6‐Methyl 3‐chromonyl 2,4‐thiazolidinedione/2,4‐imidazolidinedione/2‐thioxo‐imidazolidine‐4‐one compounds: novel scavengers of reactive oxygen species
Authors: Berczyński Paweł , Duchnik Ewa , Kruk Irena , Piechowska Teresa , Aboul‐Enein Hassan Y. , Bozdağ‐Dündar Oya , Ceylan‐Unlusoy Meltem 
Published: July 2013

ABSTRACTThe benefits of antioxidants on human health are usually ascribed to their potential ability to remove reactive oxygen species providing protection against oxidative stress. In this paper the free radicals scavenging activities of nine 6‐methyl 3‐chromonyl derivatives (CMs) were evaluated for the first time by the chemiluminescence, electron paramagnetic resonance, spin trapping and 2,2‐diphenyl‐1‐picrylhydrazyl (DPPH•) methods. The total antioxidant capacity was also measured using a ferric‐ferrozine reagent. Compounds having a hydrogen atom at the N3‐position of the β‐ring were effective in quenching CL resulted from the KO2/18‐crown‐6‐ether system (a source of superoxide anion radical, ) in a dose‐dependent manner over the range of 0.05–1 mmol/L [IC50 ranged from 0.353 (0.04) to 0.668 (0.05) mmol/L]. The examined compounds exhibited a significant scavenging effect towards hydroxyl radicals (HO• HO•), produced by the Fenton reaction, and this ranged from 24.0% to 61.0%, at the concentration of 2.5 mmol/L. Furthermore, the compounds examined were also found to inhibit DPPH• and this ranged from 51.9% to 97.4% at the same concentration. In addition, the use of the total antioxidant capacity assay confirmed that CM compounds are able to act as reductants. According to the present study, CM compounds showed effective in vitro free radical scavenging activity and may be considered as potential therapeutics to control diseases of oxidative stress‐related etiology. Copyright © 2013 John Wiley & Sons, Ltd.
Bioportides: Bioactive cell‐penetrating peptides that modulate cellular dynamics
Authors: Lukanowska Monika , Howl John , Jones Sarah 
Published: July 2013

AbstractThe study and exploitation of cell‐penetrating peptides (CPPs) now extends into a third exciting decade. Pharmacokinetic modulators, including the more common sequences Tat, penetratin and transportan‐10, markedly enhance the intracellular delivery of small drugs, peptides, oligonucleotides and proteins. We introduced the term bioportide to distinguish cell penetrant peptides with intrinsic bioactivities from more typically inert CPP vectors. Our first examples included rhegnylogically organised bioportides, monomeric peptides presenting pharmacophores for both cellular internalization and bioactivity discontinuously distributed within the primary sequence. However, it is conceptually expedient to employ the same terminology to encompass sychnologic bioportides that comprise an inert CPP vector conjugated to an otherwise impermeable bioactive peptide. In such cases the CPP provides an obvious address function whilst the bioactive cargo, often a protein mimetic sequence, is the message. Additional targeting sequences, usually added as chimeric extensions, can also be accommodated within the design of CPPs and bioportides to enable cell‐ and tissue‐selective targeting. Thus, the identification and exploitation of bioportides provides further scope to employ CPPs as research tools, diagnostics and therapeutics spanning a range of pathologies.
ChemInform Abstract: Synthesis and Characterization of Two Crystallographic Forms of Ag0.79VS2.
Authors: Ali Mazhar N. , Ji Huiwen , Hirai Daigorou , Fuccillo M. K. , Cava R. J. 
Published: July 2013

AbstractA mixture of α‐Ag0.79VS2 and β‐Ag0.79VS2 is prepared by solid state reaction of a stoichiometric mixture of Ag, V, and S powder (evacuated quartz tube, 750 °C, 6 d).
ChemInform Abstract: Preparation and Visible‐Light Photocatalytic Properties of BiNbO4 and BiTaO4 by a Citrate Method.
Authors: Zhai Hai‐Fa , Li Ai‐Dong , Kong Ji‐Zhou , Li Xue‐Fei , Zhao Jie , Guo Bing‐Lei , Yin Jiang , Li Zhao‐Sheng , Wu Di 
Published: July 2013

AbstractBiNbO4 (I) and BiTaO4 (II) powders are obtained via the sol‐gel citrate route, starting with 5% excess of Bi(NO3)3 in aqueous solutions of niobium or tantalum citrate peroxide (pH 7—8, solvent evaporation at 180 °C, 4 h, calcination at 550—1200 °C, 3 h).
ChemInform Abstract: Oxidative Diamination Promoted by Dinuclear Iodine(III) Reagents.
Authors: Roeben Caren , Souto Jose A. , Escudero‐Adan Eduardo C. , Muniz Kilian 
Published: July 2013

AbstractThe synthesis of new dinuclear iodine(III) compounds and their application in the intermolecular diamination of alkenes are described.
ChemInform Abstract: Iron‐Catalyzed N‐Alkylation Using π‐Activated Ethers as Electrophiles.
Authors: Fan Xiaohui , Fu Lin‐An , Li Na , Lv Hao , Cui Xiao‐Meng , Qi Yuan 
Published: July 2013

AbstractAn alternative access to N‐containing compounds via iron‐catalyzed substitution of π‐activated ethers is presented.
ChemInform Abstract: Nanocrystalline TiO2—HClO4: A Novel, Efficient and Recyclable Catalyst for the Chemoselective N‐Boc Protection of Amines under Solvent‐Free Conditions.
Authors: Shirini Farhad , Atghia Seyyed Vahid , Jirdehi Mojtaba Ghazi 
Published: July 2013

AbstractNotable features of the title process are mild acidic conditions, short reaction times, and room temperature.
ChemInform Abstract: Pd2dba3/Bippyphos: A Robust Catalyst System for the Hydroxylation of Aryl Halides with Broad Substrate Scope.
Authors: Lavery Christopher B. , Rotta‐Loria Nicolas L. , McDonald Robert , Stradiotto Mark 
Published: July 2013

AbstractAn efficient catalytic system for the title reaction under mild reaction conditions is presented.
ChemInform Abstract: A General Simple Methodology for Synthesis of Isonitriles Using Benzene‐1,3‐disulfonyl Dichloride.
Authors: Ghorbani‐Vaghei Ramin , Amiri Mostafa , Veisi Hojat 
Published: July 2013

AbstractA facile protocol for the efficient transformation of formamides into isonitriles using 1,3‐disulfonyl chloride as dehydration reagent is presented.
ChemInform Abstract: BF3·OEt2‐Promoted Concise Synthesis of Difluoroboron‐Derivatized Curcumins from Aldehydes and 2,4‐Pentanedione.
Authors: Liu Kai , Chen Jiangmin , Chojnacki Jeremy , Zhang Shijun 
Published: July 2013

AbstractOptimized conditions are elaborated for the preparation of various symmetrical and unsymmetrical title compounds, which are of interest in drug development.
ChemInform Abstract: Unexpected O‐Alkylation and Ester Migration in Phenolic 2,3‐Diaryl‐2,3‐dihydrobenzo[b]furans.
Authors: Tran Henry , Dickson Benjamin D. , Barker David 
Published: July 2013

AbstractAttempted O‐alkylation of benzodihydrofuran derivative (I) proceeds through an unexpected hydrolysis of the nitrobenzoate esters accompanied by transfer of a ‐Pnb group to the aromatic 5‐OH and double alkylation of the newly generated 3,5‐dihydroxyphenyl moiety.
ChemInform Abstract: Asymmetric Catalytic Aza‐Morita—Baylis—Hillman Reaction for the Synthesis of 3‐Substituted‐3‐aminooxindoles with Chiral Quaternary Carbon Centers.
Authors: Hu Fang‐Le , Wei Yin , Shi Min , Pindi Suresh , Li Guigen 
Published: July 2013

AbstractThe title reaction is studied using β‐isocupreidine and 2‐(OH)‐2′‐(PPh2)‐1,1′‐binaphthyl as comparable chiral catalysts.
ChemInform Abstract: A Cascade Approach to Fused Indolizinones Through Lewis Acid—Copper(I) Relay Catalysis.
Authors: Huang Huawen , Ji Xiaochen , Wu Wanqing , Jiang Huanfeng 
Published: July 2013

AbstractA novel synthesis of fused indolizidinones from cyclopropyl ketones and nitriles using a Lewis acid‐Cu(I) binary catalytic system is described.
ChemInform Abstract: Domino o‐Alkylation and Heteroarylation of Iodoarenes: One‐Pot Synthesis of Benzocyclohepta[b]indoles.
Authors: Jafarpour Farnaz , Otaredi‐Kashani Asieh , Behpajooh Saeideh 
Published: July 2013

AbstractVarious derivatives of the medicinally interesting heterocyclic scaffold are prepared which, in part, include substituents for further functionalization.
ChemInform Abstract: Chemoselective and Regiospecific Formylation of 1‐Phenyl‐1H‐pyrazoles Through the Duff Reaction.
Authors: Menegatti Ricardo , et al. et al. 
Published: July 2013

Abstract1‐Arylpyrazoles of type (I), (IV), or (VI) are formylated using hexamethylenetetramine as formylating agent.
ChemInform Abstract: Synthesis and Antifungal Evaluation of 7‐Arylamino‐5,8‐dioxo‐5,8‐dihydroisoquinoline‐4‐carboxylates.
Authors: Ryu Chung‐Kyu , Song Ae Li , Hong Jung An 
Published: July 2013

AbstractA variety of the title isoquinolinecarboxylate derivatives are synthesized by nucleophilic substitution reactions.
ChemInform Abstract: Synthesis of 2‐Thia‐4‐azabicyclo[3.3.1]non‐3‐en‐3‐amine — Bridged Nitric Oxide Synthase Inhibitor with Enhanced Lipophilicity.
Authors: Zefirova Olga N. , Plotnikova Evgeniya D. , Nurieva Evgeniya V. , Peregud Danil I. , Onufriev Mikhail V. , Gulyaeva Natalia V. 
Published: July 2013

AbstractA synthesis is given for title compound (XIII) which is found to be a potent inhibitor of inducible NO‐synthase in vitro.
ChemInform Abstract: Mild and Efficient Synthesis of Benzo‐Fused Seven‐ and Eight‐Membered Ring Lactams: A Convenient Approach to Biologically Interesting Chemotypes.
Authors: Kenwright Jayne L. , Galloway Warren R. J. D. , Wortmann Lars , Spring David R. 
Published: July 2013

AbstractThe title compounds (II) are efficiently obtained via Beckmann rearrangement of cyclic oximes.
ChemInform Abstract: Preparation of Sugar‐Derived 1,2‐Diamines via Indium‐Catalyzed Aza‐Henry‐Type Reaction: Application to the Synthesis of 6‐Amino‐1,6‐dideoxynojirimycin.
Authors: Soengas Raquel G. , Silva Artur M. S. 
Published: July 2013

AbstractOptimized conditions are developed for the synthesis of nitroamines (III) via In‐catalyzed addition of bromonitroalkanes to imines.
Efficient parallel implementation of three‐point viterbi decoding algorithm on CPU, GPU, and FPGA
Authors: Li Rongchun , Dou Yong , Zou Dan 
Published: July 2013

SUMMARYIn wireless communication, Viterbi decoding algorithm (VDA) is the one of most popular channel decoding algorithms, which is widely used in WLAN, WiMAX, or 3G communications. However, the throughput of Viterbi decoder is constrained by the convolutional characteristic. Recently, the three‐point VDA (TVDA) was proposed to solve this problem. In TVDA, the whole procedure can be divided into three phases, the forward, trace‐back, and decoding phases. In this paper, we analyze the parallelism of TVDA and propose parallel TVDA on the multi‐core CPU, graphics processing unit (GPU), and field programmable gate array (FPGA). We demonstrate approaches that fully exploit its performance potential on CPU, GPU, and FPGA computing platforms. For CPU platforms, we perform two optimization methods, single instruction multiple data and multithreading to gain over 145 × speedup over the naive CPU version on a quad‐core CPU platform. For GPU platforms, we propose the combination of cached memory optimization, coalesced global memory accesses, codeword packing scheme, and asynchronous data transition, achieving the throughput of 404.65 Mbps and 12 × speedup over initial GPU versions on an NVIDIA GeForce GTX580 card and 7 × speedup over Intel quad‐core CPU i5‐2300, under the same manufacturing year and both with fully optimized schemes. In addition, for FPGA platforms, we customize a radix‐4 pipelined architecture for the TVDA in a 45‐nm FPGA chip from Xilinx (XC6VLX760). Under 209.15‐MHz clock rate, it achieves a throughput of 418.30 Mbps. Finally, we also discuss the performance evaluation and efficiency comparison of different flexible architectures for real‐time Viterbi decoding in terms of the decoding throughput, power consumption, optimization schemes, programming costs, and price costs.Copyright © 2013 John Wiley & Sons, Ltd.
A Closer Look at the ‘Global Reporting Initiative’ Sustainability Reporting as a Tool to Implement Environmental and Social Policies: A Worldwide Sector Analysis
Authors: del Mar Alonso‐Almeida María , Llach Josep , Marimon Frederic 
Published: July 2013

ABSTRACTThis study analyses the worldwide diffusion of the Global Reporting Initiative's (GRI) Sustainability Report in all economic sectors from 1999 to 2011. The logistic curve model (s‐shaped curve) is used to assess the current situation on both a global scale and a local scale. Additionally, instability and concentration indices are used to analyse whether the diffusion process developed in a homogeneous manner across economic sectors. Although for different reasons, close attention has been paid to the two leading sectors worldwide: the financial and energy sectors. Findings suggest that the energy sector has adopted GRI reporting in an effort to be more sustainable as it is more visible, polluting, and international. On the other hand, the financial sector could regain market credibility and attract new investors, and GRI reporting could help it to construct a new identity defined by legitimate behaviours and an improved image. The paper concludes with some reflections on the usefulness of these reports and trends. Copyright © 2013 John Wiley & Sons, Ltd and ERP Environment
Effect of Financial Reporting Quality on Sustainability Information Disclosure
Authors: Martínez‐Ferrero Jennifer , Garcia‐Sanchez Isabel M. , Cuadrado‐Ballesteros Beatriz 
Published: July 2013

AbstractInterest in corporate social responsibility (CSR) information has increased in recent years. This has led companies to set aside the classic economic view and to adopt the ‘triple bottom line’, reporting social, environmental, and financial information, in order to satisfy their stakeholders' needs.Companies that provide high quality financial information tend to be more conservative in their accounting and less inclined to carry out unethical practices such as earnings management. Accordingly, they are more socially responsible. The aim of this paper is to analyse the relationship between financial reporting quality and the quality of CSR information. To do so, we studied a sample composed of 747 international listed non‐financial companies for the period 2002–2010. The results obtained from a Tobit method for panel data show that conservative companies, with a high level of accruals quality and/or those that carry out earnings management practices to a lesser extent, report high quality financial information and, moreover, high quality CSR information. Copyright © 2013 John Wiley & Sons, Ltd and ERP Environment.
The menopausal transition—A possible window of vulnerability for eating pathology
Authors: Mangweth‐Matzek Barbara , Hoek Hans W. , Rupp Claudia I. , Kemmler Georg , Pope Harrison G. , Kinzl Johann 
Published: July 2013

ABSTRACTObjectiveNo published studies, to our knowledge, have examined the association of menopausal status with eating disorders and body image in women. We assessed these associations in a large sample of middle‐aged women.MethodWe administered an anonymous questionnaire to a randomly selected nonclinical sample of women aged 40–60 in Innsbruck, Austria. The questionnaire covered demographic items, menopausal status, weight history, measures of body image, and current eating disorders as diagnosed by DSM‐IV criteria. Using modified WHO criteria, we classified the respondents' current stage of menopausal transition as premenopausal (N = 192), perimenopausal (N = 110), or naturally postmenopausal (N = 134). In a separate analysis, we also examined the small group of women with surgically induced menopause (N = 12).ResultsThe three groups were similar in all demographic features except age, and did not differ significantly on current body mass index (BMI), weight‐control behaviors, or dieting history after age adjustment. However, perimenopausal women reported a significantly greater prevalence of eating disorders as compared to premenopausal women. Perimenopausal women also reported significantly higher self‐ratings of “feeling fat” and higher Body Shape Questionnaire scores than premenopausal women. Women with surgically induced menopause also showed an elevated prevalence of eating and body image pathology.DiscussionOur data suggest that the menopausal transition is associated with an increased prevalence of eating disorders and negative body image. Menopause, like puberty, may perhaps represent a window of vulnerability to these conditions, likely because of changes in hormonal function, body composition, and conceptions of womanhood. © 2013 Wiley Periodicals, Inc. (Int J Eat Disord 2013; 46:609–616)
Parent–child concordance in reporting of child eating disorder pathology as assessed by the eating disorder examination
Authors: Mariano Paige , Watson Hunna J. , Leach David J. , McCormack Julie , Forbes David A. 
Published: July 2013

ABSTRACTObjectiveThe aim of this study was to examine parent–youth concordance in reporting of eating disorder pathology, as assessed by the Eating Disorder Examination (EDE) in a clinical pediatric sample.MethodThe sample comprised 619 parent‐youth dyads of youth (8–18 years) presenting for treatment at a specialist eating disorder clinic. A cross‐sectional correlational design was used to examine the association between parent and youth symptom reports.ResultsOn the whole, parent–youth inter‐rater agreement was poor to moderate. Agreement was acceptable for the presence of behavioral symptoms, with the exception of excessive exercise (PAK = 0.48–0.98). There was poor inter‐rater agreement on frequency of behavioral symptoms, with parents providing lower estimates than youth (ICC = 0.07–0.52). Although we predicted that inter‐rater agreement on cognitive symptoms would by higher with adolescents than children, both groups were discordant with parent reports. Younger children identified less severe eating disorder cognitions than parents and the opposite occurred for adolescents. An anorexia nervosa presentation and lower malnutrition were not associated with lower inter‐rater agreement, as might have been expected through ego syntonicity. Youth with bulimia nervosa presentations reported significantly higher severity of cognitive symptoms and more frequent disordered eating behaviors compared with their parents.DiscussionResults support the utility of parent–youth assessment via the EDE to obtain a wider clinical picture of eating disorder psychopathology in children and adolescents, particularly for younger children. Clinical implications pertinent to administration of the EDE and parent literacy regarding eating disorder symptoms are discussed. © 2013 Wiley Periodicals, Inc. (Int J Eat Disord 2013; 46:617–625)
Weighted Empirical Likelihood Estimator for Vector Multiplicative Error Model
Authors: Ding Hao , Lam Kai‐pui 
Published: July 2013

ABSTRACTThe vector multiplicative error model (vector MEM) is capable of analyzing and forecasting multidimensional non‐negative valued processes. Usually its parameters are estimated by generalized method of moments (GMM) and maximum likelihood (ML) methods. However, the estimations could be heavily affected by outliers. To overcome this problem, in this paper an alternative approach, the weighted empirical likelihood (WEL) method, is proposed. This method uses moment conditions as constraints and the outliers are detected automatically by performing a k‐means clustering on Oja depth values of innovations. The performance of WEL is evaluated against those of GMM and ML methods through extensive simulations, in which three different kinds of additive outliers are considered. Moreover, the robustness of WEL is demonstrated by comparing the volatility forecasts of the three methods on 10‐minute returns of the S&P 500 index. The results from both the simulations and the S&P 500 volatility forecasts have shown preferences in using the WEL method. Copyright © 2012 John Wiley & Sons, Ltd.
Mild cognitive impairment in Parkinson's disease is associated with a distributed pattern of brain white matter damage
Authors: Agosta Federica , Canu Elisa , Stefanova Elka , Sarro Lidia , Tomić Aleksandra , Špica Vladana , Comi Giancarlo , Kostić Vladimir S. , Filippi Massimo 
Published: July 2013

AbstractThis study assesses the patterns of gray matter (GM) and white matter (WM) damage in patients with Parkinson's disease and mild cognitive impairment (PD‐MCI) compared with healthy controls and cognitively unimpaired PD patients (PD‐Cu). Three‐dimensional T1‐weighted and diffusion tensor (DT) magnetic resonance imaging (MRI) scans were obtained from 43 PD patients and 33 healthy controls. Cognition was assessed using a neuropsychological battery. Tract‐based spatial statistics was applied to compare DT MRI indices between groups on a voxel‐by‐voxel basis. Voxel‐based morphometry was performed to assess GM atrophy. Thirty PD patients were classified as MCI. Compared with healthy controls, PD‐Cu and PD‐MCI patients did not have GM atrophy. No region of WM damage was found in PD‐Cu patients when compared with healthy controls. Relative to healthy controls and PD‐Cu patients, PD‐MCI patients showed a distributed pattern of WM abnormalities in the anterior and superior corona radiata, genu, and body of the corpus callosum, and anterior inferior fronto‐occipital, uncinate, and superior longitudinal fasciculi, bilaterally. Subtle cognitive decline in PD is associated with abnormalities of frontal and interhemispheric WM connections, and not with GM atrophy. DT MRI might contribute to the identification of structural changes in PD‐MCI patients prior to the development of dementia. Hum Brain Mapp 35:1921–1929, 2014. © 2013 Wiley Periodicals, Inc.
Hydrologic evaluation of spatially disaggregated global ensemble rainfall forecasts
Authors: Gaborit E. , Anctil F. , Fortin V. , Pelletier G. 
Published: July 2013

AbstractA statistic–stochastic multi‐fractal downscaling technique was evaluated from a hydrologic point of view. Ensemble hydrologic forecasts with a time step of 3 h were performed for original and disaggregated ensemble rainfall forecasts issued by the Canadian Global Ensemble Prediction System in its 2009 operational version. This hydro‐meteorological operational forecasting chain was conducted using the hydrological model SWMM5. The model was implemented on a small 6‐km2 urban catchment located in the Québec City region. The hydrological evaluation was based on the comparison of forecasted flows to the observed ones, calculating several deterministic and probabilistic scores, and drawing rank histograms and reliability diagrams. Disaggregated products led to a better representation of the ensemble members' dispersion. This disaggregation technique represents an interesting way of bridging the gap between the meteorological models' resolution and the high degree of spatial precision sometimes required by hydrological models in their precipitation representation. Copyright © 2013 John Wiley & Sons, Ltd.