bluuebunny/crossref_metadata_2025_split huggingface dataset:
Latin American adults who regularly use macrodoses of psychedelics: a cross-sectional study
Authors: Véliz-García Oscar , Domic Marcos 
Published: August 2024

Abstract

Psychedelics have a complex history marked by traditional use among indigenous cultures, early scientific interest, and subsequent prohibition. Despite their classification as controlled substances, recent decades have witnessed a resurgence of research into their therapeutic potential for various mental health conditions. However, most studies have focused on controlled clinical settings, leaving a significant gap in understanding how these substances are used in naturalistic contexts, particularly in Latin America. This study investigates the regular use of macrodoses of psychedelics among Latin American adults. We aimed to characterize the sociodemographic profiles, consumption practices, and subjective effects experienced by individuals who use psychedelics regularly. Data were collected via an online survey from 4,270 participants across several Latin American countries. Results indicated a diverse user base with varied motivations, predominantly psychological and spiritual well-being. The most frequently used substance was psilocybin mushrooms, with significant associations found between demographic variables and specific psychedelics used. The study provides new insights into the naturalistic use of psychedelics in Latin America, highlighting the need for informed, safe, and legal use frameworks.
Program to optimise detecting growth hormone deficiency in children and increase adherence to replacement therapy
Authors: Aryayev M.L. , Senkivska L.I. , Senkivska Y.D. 
Published: July 2024

Background. The significance of this study lies in the fact that short stature is highly prevalent among children, affec­ting 1–5 % of the population and having diverse causes. The child’s growth potential in the long term is largely depends on the effectiveness of the diagnostic system and the level of adherence to the prescribed therapy. The purpose was to improve the diagnosis of growth hormone deficiency (GHD) in children and adherence to recombinant human growth hormone (rhGH) therapy based on information about the regional prevalence of the disease and barriers to adherence. Materials and methods. A follow-up study was conducted from 2012 to 2020 at the Odesa Regional Children’s Hospital. The cohort included 94 children with GHD. The prevalence was determined by calculating the ratio of the number of all detected GHD cases to the children population per 100,000. Adherence was measured using the Morisky Medication Adherence Scale. The statistical processing of the results was done using t-test and chi-square methods, and p-values less than 0.05 were considered statistically significant. Results. An assessment of GHD prevalence, the level of adherence and the frequency of continuity of rhGH therapy in children in the Odesa region at the end of 2014 revealed the incompleteness of regional diagnosis of the disease (in Odesa, 1 : 11,200; in the Odesa region, 1 : 10,800), as well as a low level of acceptable adhe­rence (in 57.4 %) and insufficient frequency of continuity of therapy (in 76.9 %). These data formed the basis of the regional program for optimizing the identification and management of GHD in children, which included organizational, medical and social measures. By the end of 2020, the prevalence of GHD in Odesa was 1 : 4,300, and in the Odesa region, 1 : 5,100. The rate of acceptable adherence to rhGH therapy increased to 80.0 %, and frequency of continuity of therapy to 91.1 %. Conclusions. The regional program designed to improve the detection and management of GHD in children has been found to improve the diagnosis of the disease, increase adhe­rence to rhGH therapy, and the frequency of continuity of treatment. High adherence to treatment is a bioethical issue because it signifies a good partnership between physicians, children, and parents and indicates respect for patient autonomy.
Factors of postembryonic ontogeny: relationship with the effectiveness of tuberculosis chemoprophylaxis in children
Authors: Bodnia K.I. , Zosimov A.M. , Asoyan І.M. , Kondratyuk V.V. , Navet T.І. , Khodosh E.M. , Makarenko V.D. 
Published: July 2024

Background. A child’s body as a functional system is formed starting from the fetal period. Therefore, analysis of even distant in time situations allows to identify factors that affect the functioning of the child’s body in the present time and, possibly, the effectiveness of chemoprophylaxis in children. Materials and methods. To study the presence of a correlation between factors of postembryonic ontogeny and the effectiveness of chemoprophylaxis of tuberculosis in children, an analysis was carried out of 300 patients aged 0 to 17 years in the early period of primary tuberculosis infection, who underwent a 3-month course of chemoprophylaxis with isoniazid. The dynamics of shin sensitivity according to the Mantoux test with 2 tuberculin units was used as a criterion for the effectiveness of chemoprophylaxis. Depending on the latter, the exa­minees were divided into two groups: a group with effective chemoprophylaxis (n = 200), in which the size of a wheal after the end of the course decreased by 4 mm or more, and a group with ineffective chemoprophylaxis, in which skin sensitivity to tuberculin increased or remained at the previous level or decreased in the size of a wheal by 3 mm or less. Results. The analysis showed that in the group with ineffective chemoprophylaxis compared to the alternative group, the following occurred significantly more often: short-term (up to 4 months) breast feeding, a history of acute bronchitis (p < 0.001) in a child, acute obstructive bronchitis. In addition, the following were characteristic of this group: the presence of tuberculosis contact (p < 0.001), tuberculosis contact with a patient with confirmed bacterial excretion (p < 0.001), age of child under 6 years (p < 0.001), the number (two and more) of concomitant pathologies (p < 0.001), a single BCG vaccination (p < 0.001), as well as the winter seasona­lity of chemoprophylaxis (p < 0.05). Conclusions. Significant correlations have been found between many factors of postembryonic ontogeny and the effectiveness of tuberculosis chemoprophylaxis in children, which allows them to be used for prognostic purposes. The closest connections with the effectiveness of chemoprophylaxis of tuberculosis in children was revealed for the presence of tuberculosis contact (ϕ = 1.08; p < 0.001), especially with a patient with confirmed bacterial excretion (ϕ = 1.72; p < 0.001), as well as the number of concomitant pathologies in a child (ϕ = 0.70; p < 0.001) and manifestations of allergy (ϕ = 0.67; p < 0.001).
Monitoring the level of satisfaction with the quality of training in pediatrics of undergraduates on the specialty 222 “Medicine” of the Faculty for Training of Foreign Citizens of the Bogomolets National Medical University
Authors: Gryshchenko N.V. , Kovalchuk O.L. 
Published: July 2024

Background. Monitoring the level of satisfaction of undergraduates on the specialty 222 “Medicine” concerning their training in pediatrics and the level of mastering the necessary competencies is an important marker that allows timely assessment of the quality of the educational services provision, as well as the improvement and expansion of their range in relation to the students’ needs. Objective: to analyze the satisfaction level of the students’ training in pediatrics and to determine ways of improving the teaching of pediatric disciplines to the 6th year foreign students on the specialty 222 “Medicine” at the Department of Pediatrics 2 of the Bogomolets National Medical University based on the anonymous survey results. Materials and methods. The survey was conducted using 4–5-point Likert scale questionnaire in Google Form. Results. Practically all students were basically satisfied with the knowledge obtained in pediatric disciplines they studied at the Department of Pediatrics 2 from the 2nd to the 6th years, with a special emphasis on preparation during the graduation year. Only one third (34.7 %) of respondents in general noted that the organization and delivery of an online training did not deteriorate the quality of knowledge and practical skills in pediatrics. The respondents were particularly interested in sections of pediatrics such as cardiology, rheumatology, pulmonology and neonatology. The insufficient satisfaction of higher education seekers with level of their knowledge in propaedeutics of pediatrics, pathology of young children and pediatric cardiology requires a corresponding correction of the curriculum — an increase in the number of academic hours in these sections of pediatrics and more effective use of the self-directed independent learning. Conclusions. Monitoring the satisfaction level is an effective method of communication with medical undergraduates aimed at identifying problems and improving the effectiveness of training and educational process for foreign students, who in general positively evaluated the results of their five-year study of pediatric disciplines at the Department of Pediatrics 2 of the Bogomolets National Medical University.
Particulars of breastfeeding age in preterm child (case report)
Authors: Bulat L.M. , Lysunets O.V. , Didyk N.V. 
Published: July 2024

Background. General physicians often encounter preterm infants and adverse sequelae of prematurity-related morbidities. Interruption of intrauterine development leads to considerable deficits in the internal organs structure and function. It can lead to endothelial dysfunction, hypertension, proteinuria and metabolic abnormalities that persist throughout life. Children born early or low birth weight (LBW) infants also have relatively increased risk for the deve­lopment of kidney injury later in life. Often these infants have history of treatment at the intensive care unit due to hypoxic damage or inflammatory response that also affects kidneys necessitating the use of nephrotoxic medications. The treatment and diagnosis outcomes were applied to make a conclusion about clinical features of the preterm 7-month-old girl. The data were analyzed using PubMed/MEDLINE and Google Scholar databases. The aim is to summarize particulars of breastfeeding period in a LBW baby, providing a physician with practical information regar­ding organization of a follow-up. Material and methods. The baby was moderately preterm (32–33 weeks of gestation) with LBW (2100 g). Her mother was consulted regarding hypertension and threat of miscarriage during pregnancy. The child had renal borderline states in the newborn period. Apgar score was low, neonatal resuscitation and respiratory support by the continuous positive airway pressure were used. The newborn had poor regulation of body temperature, depended on environmental factors and prone to rapid heat loss, so she was nursed in incubator. A feeding tube was used despite poor sucking at the first days after delivery and breastfeeding was continued as soon as possible. Eventually, formula feeding was started. Results. Fever, vomiting, dehydration, loss of body weight and oliguria appeared in the 7-month-old baby after the upper respiratory tract infection. Examination showed the stigmas, neurodevelopmental delay, physical growth gap. Blood tests revealed anemia of the first stage and a rapid increase in the level of white blood cells with a left shift and electrolyte imbalance. The laboratory tests of primary and secondary hemostasis were normal. Physical, chemical and microscopic urine properties were changed according to results of urine test. The sonography revealed changes in renal tissue and thymic hyperplasia. The child was diagnosed with acute pyelonephritis and treated. Conclusions. Physicians should focus attention on the stigmas, neurodevelopmental delay, physical growth gap, life history, clinical signs and results of examination to make timely conclusion about child’s general state. Kidney injury could be diagnosed in preterm LBW infants.
Reproducible and Attributable Materials Science Curation Practices: A Case Study
Authors: Li Ye , Wilson Sara , Altman Micah 
Published: July 2024

While small labs produce much of the fundamental experimental research in Material Science and Engineering (MSE), little is known about their data management and sharing practices and the extent to which they promote trust in, and transparency of, the published research.
In this research, we conduct a case study of a leading MSE research lab to characterize the limits of current data management and sharing practices concerning reproducibility and attribution. We systematically reconstruct the workflows, underpinning four research projects by combining interviews, document review, and digital forensics. We then apply information graph analysis and computer-assisted retrospective auditing to identify where critical research information is unavailable or at risk.
We find that while data management and sharing practices in this leading lab protect against computer and disk failure, they are insufficient to ensure reproducibility or correct attribution of work — especially when a group member withdraws before project completion.
We conclude with recommendations for adjustments to MSE data management and sharing practices to promote trustworthiness and transparency by adding lightweight automated file-level auditing and automated data transfer processes.
GRUPO DE CONVIVÊNCIAS INFANTIL À LUZ DO CONCEITO DE EXPERIÊNCIA DE JORGE LARROSA BONDÍA: RELATO DE CASO
Authors: Soares Fernanda Vieira , Pitombeira Mardênia Gomes Vasconcelos , Soares Ângela Vieira , Castro Evelyne Ferreira de , Sousa Edilson Oliveira de , Fernández Carmen Adriana 
Published: August 2024

O objetivo deste estudo é descrever o funcionamento do grupo de convivências como estratégia de cuidados com crianças. Metodologia: abordagem qualitativa, observação participante, diário de bordo e relato de caso. Como resultados: o detalhamento dos acontecimentos em um dia no parque de aventuras incluindo desde o planejamento até a finalização do encontro destacando, o roteiro prático das atividades propostas.Para subsidiar esta intervenção infantil, a secção da discussão apresenta fundamentos teóricos a partir do conceito de experiência por Jorge Larrosa Bondía assim como, sobre o sujeito da experiência e o saber da experiência. O trabalho alcançou o objetivo proposto, na perspectiva de ampliar as possibilidades de intervenção multiprofissional voltados à infância.
Jambi Community Trust in Local Government; Mandatory Coronavirus-19 Vaccination
Authors: Yohanes Yulius , Elyta Elyta , Apriyani Eka , Pribadi Ulung , Istiqoh Akhdiva Elfi , Asriadi Asriadi 
Published: July 2024

This study analyses the Jambi people's trust in the local government regarding the obligation to vaccinate against Covid-19. To make it easier for the public to access and complete voluntary questionnaires, one hundred respondents completed a survey using a Google form. This study used a quantitative method with four independent variables that influence perceptions of responsiveness, perceptions of accountability, perceptions of transparency, and perceptions of usability. The findings of this study indicate that perceived responsiveness and transparency have a positive and significant influence in encouraging Jambi people's trust. The achievement of p-value perceived responsiveness (0.026) and perceived transparency (0.014) means that the results are supported and accepted. Meanwhile, the variables perceived accountability (0.284), and perceived usefulness (0.078) indicate that these two variables have no significant effect and are rejected. Local governments need to pay attention to perceptions of responsiveness and perceptions of transparency so that the mandatory COVID-19 vaccination policy can work and be well received by the community and does not become a paradox of public administration.
MENERAPKAN NILAI-NILAI PEMIKIRAN DEWI SARTIKA DALAM PENDIDIKAN MODERN
Authors: Tahimu Muhammad Reza 
Published: July 2024

Dewi Sartika, a national hero of Indonesia, is known as a pioneer of education for women. Her thoughts on education are still relevant today, amidst the modern era full of challenges and changes. The values of Dewi Sartika's thoughts, such as noble character, intelligence, and independence, can be a guide in implementing quality and character-based education in the modern era. This study aims to identify the values of Dewi Sartika's thoughts on education and analyze their relevance in modern education. The research method used is a qualitative research method with a literature study approach. Data was collected through literature studies, including books, scientific journals, online articles, and official documents. The data were then analyzed using a descriptive-analytic method. The results of the study show that the values of Dewi Sartika's thoughts on education are still relevant in modern education. These values can be implemented in various ways, such as integrating moral values and noble character into the curriculum and learning, developing character education through various programs and activities, providing opportunities for students to learn independently and creatively, and utilizing information and communication technology to support learning. There are also challenges and opportunities in implementing the values of Dewi Sartika's thoughts on education in modern education. The challenges include globalization and the influence of foreign cultures that can erode local cultural values, a lack of awareness and commitment from various parties to implement character education, and limited educational resources and infrastructure. However, there are also opportunities, such as increasing public awareness of the importance of character education, the development of information and communication technology that can support learning, and support from the government and various parties to improve the quality of education.
Keywords: education, character education, modern education, Indonesia
MENINGKATKAN KEMAMPUAN ANAK USIA DINI DALAM MENGENAL HURUF MELALUI PERMAINAN KOTAK ALFABET
Authors: Salam Abdul , Larau Sri Amini Fadhila , Husen  
Published: July 2024

The research problem was whether the abilitiy to recognize children in group A could increase after using the alphabet box game in East Longkoga ABA Kindergarten. The research subjects consisted of 10 students, with four boys and six girls. The research was conducted in two cycles, each consisting of two meetings. Learning activities consist of four stages, namely the planning stage, the implementation stage, the observation, and the reflection stage. Data collection techniques used in this study are observation and documentation sheets. Data analysis was carried out in a comparative descriptive manner, namely comparing the values between cycles processed using the percentage calculation (%) according to the formula. The research results show that on the indicator of the ability to recognize the alphabet at the pre-cycle stage, there were six students, or 60% who reached the Beginning to Develop category. At the end of the cycle I, six students or 60%, reached the Expected Developing category. At the end cycle II, nine students or 90% reached the Very Good Development category.
Furthermore, two students or 20%, reached the Beginning to Develop category in the indicator of the ability to pronounce alphabetic forms in the pre-cycle stage. At the end of the cycle I, four students or 40%, started to reach the Expected Developing category. At the end of cycle II, nine students or 90%, were in the Very Good Developing category. Finally, indicators of the ability to pronounce the alphabet at the pre-cycle stage have four students or 40%, in the Beginning to Develop category. At the end of the cycle I, two students or 20%, had reached the Expected Developing category, and one students or 10%, had reached the Very Good Developing category. And at the end of cycle II, nine students or 90% , were already in the Very Good Developing category. Based on the research above, alphabet box games can improve the ability to recognize letters in group A children in East Longkoga ABA Kindergarten.
مساهمة نظم المعلومات الإدارية في تقديم الخدمات للمتدربين بمعهد الإدارة العامة بالرياض، المملكة العربية السعودية
Authors: العقيل أحمد سعود 
Published: July 2024

تتمثل مشكلة الدراسة حول التعرف على نظم المعلومات الإدارية ودورها في تقديم الخدمات للمتدربين من الأجهزة الحكومية في مدينة الرياض. وتبرز الأهمية العلمية لهذه الدراسة إلى ما أحدثت نظم المعلومات الإدارية من تطور كبير في جميع مناحي الحياة، وفي مجال التنمية الإدارية على وجه الخصوص، فقد أصبحت معظم المنظمات تعتمد على نظم المعلومات الإدارية وأنظمة الحاسوب، حيث تكمن أهمية البحث من خلال عدم قدرة الوسائل التقليدية على توفير المعلومات الملائمة للمتدربين بالكيفية المناسبة لتحسين الخدمة، وتهدف الدراسة إلى التعرف على واقع أثر استخدام نظم المعلومات الإدارية في معهد الإدارة العامة بالرياض، ومستوى الخدمات المقدمة للمتدربين من معهد الإدارة العامة بالرياض، ومدى إسهام نظم المعلومات الإدارية في تحسين وتطوير الخدمات للمتدربين، ولتحقيق الأهداف تم استخدام أسلوب المهنج الوصفي، ولجمع البيانات تم استخدام المعاينة العشوائية على عينة قوامها( 384) من موظفي الجهات الحكومية المستفيدة من خدمات التدريب بمعهد الإدارة العامة بالرياض ، وتوصلت الدراسة إلى أن أفراد عينة الدراسة موافقون بدرجة كبيرة على واقع نظم المعلومات الإدارية في معهد الإدارة العامة بالرياض ، كما أفراد عينة الدراسة موافقون على ارتفاع مستوى الخدمات المقدمة للمتدربين بمعهد الإدارة العامة بالرياض. ومدى إسهام نظم المعلومات الإدارية في تحسين وتطوير الخدمات للمتدربين، كما توصلت الدراسة إلى أن موقع المعهد الإلكتروني يوفر معلومات عن الأهداف التفصيلية للبرامج التدريبية حسب المسمى الوظيفي بما يلبي الاستفسارات في هذا الجانب من قبل المتدربين والعمل على تسهيل وتيسير عملية التواصل مع إدارة الموقع الإلكتروني للمعهد من قبل المتدربين.