bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tissue Engineering of Nanosilver-embedded Peripheral Nerve Scaffold to Repair Nerve Defects under Contamination Conditions
Authors: Ding Tan , Yin Jun-Bin , Hao Hu-Ping , Zhu Chao , Zhang Ting , Lu Ya-Cheng , Wang Li-Ying , Wang Zhe , Li Yun-Qing 
Published: October 2015

Introduction We employed a nanosilver-collagen scaffold and tested its effects on inhibiting bacteria and facilitating nerve regeneration. Methods Based on our previous research, we prepared bionic scaffolds with different concentrations of nanosilver and examined their internal structures by scanning electron microscopy and energy dispersive spectroscopy. We implanted these scaffolds or autologous nerve grafts into rats to repair a 10-mm injury of the sciatic nerve. Results The 2 mg/ml group showed a >10 mm bacterial inhibition zone in all 3 types of bacterial culture dishes. At day 60 postsurgery, the 2 mg/ml group also showed the highest amplitude of evoked potential (AMP) and nerve conduction velocity (NCV). The regenerating nerves in the 2 mg/ml group were denser and more mature, and with thicker and well-arrayed myelin sheath. Conclusions These results demonstrate that nanosilver scaffolds (2 mg/ml group) were effective in inhibiting bacteria both in vitro and in vivo, and reduced the contamination-caused immune responses, which in turn promoted nerve regeneration and functional recovery.
When Curing a Pediatric Tumor is not Enough: The Case of a Psychiatric Disorder in a Woman Surviving Osteosarcoma
Authors: Meazza Cristina , Veneroni Laura , Podda Marta , Terenziani Monica , Luksch Roberto , Ferrari Andrea , Catania Serena , Schiavello Elisabetta , Giacon Barbara , Puma Nadia , Bergamaschi Luca , Roncari Luisa , Clerici Carlo Alfredo 
Published: October 2015

Aims and background We describe the case of a woman cured of osteosarcoma who took part in a mono-institutional study using different questionnaires to assess pediatric cancer survivors’ quality of life and behavioral features 12 years after completing her cancer treatment. Results The high levels of psychological distress and psychopathologic symptoms revealed by this patient prompted us to offer her specific and prolonged support at our institution, since she refused to seek the help of other psychiatric services. The woman revealed a dysfunctional social and family setting and a borderline personality disorder. She was hospitalized after attempting suicide. No psychological distress had previously come to light during her long follow-up for cancer. Conclusions Cancer survivors are at risk of psychological and behavioral problems, so they should be followed up over time. Questionnaires and standard scales are important, but not enough: the physician-patient relationship is crucial to bring out a patient's psychological issues and needs. This means that dedicated resources should be made available, whenever possible.
Hepatosplenic T-Cell Lymphoma with Coexistent Hepatitis B Infection: A Rare Clinicopathologic Entity
Authors: Siraj Fouzia , Dalal Varsha , Khan Afaq A. , Jain Deepali 
Published: October 2015

Background Hepatosplenic T-cell lymphoma (HSTL) is a rare extranodal and systemic lymphoma derived from cytotoxic T cells usually of γδ T cell receptor type. It is characterized by primary extranodal disease with typical sinusoidal infiltration of liver, spleen, and bone marrow by medium-sized lymphoid cells. Case Report A 29-year-old man, with no significant prior medical history, presented with fever and massive splenomegaly. A diagnosis of HSTL was established by histologic examination and immunohistochemistry. Staging workup demonstrated bone marrow involvement by lymphoma. In addition, the patient was found to have hepatitis B infection. The association of these 2 entities has been described rarely. Conclusions Hepatosplenic T-cell lymphoma is a distinct T cell lymphoma associated with an aggressive clinical course, a poor response to conventional treatment, and an exceedingly high mortality rate. An association of HSTL with hepatitis B as seen in the present case is exceedingly rare, with few cases reported in the literature.
Multilevel regulation op het terrein van de lucht-, zee- en binnenvaart
Authors: Kohll N. 
Published: October 2015

Multilevel regulation op het terrein van de lucht-, zee- en binnenvaart
Dit artikel gaat over multilevel regulation in de luchtvaart-, zeevaart- en binnenvaartwetgeving. Multilevel regulation ontstaat doordat naast nationale overheden ook veel andere organisaties regelgeving tot stand brengen. Aan de hand van steeds een actueel dossiers uit elk van de drie genoemde wetgevingscomplexen, wordt in dit artikel beschreven hoe regelgeving op internationaal niveau tot stand komt, de regelgeving van de Europese Unie beïnvloedt en uiteindelijk doorwerkt in nationale regelgeving. Ook wordt beschreven hoe in elk van de genoemde wetgevingscomplexen de wisselwerking tussen deze niveaus in de praktijk werkt, hoe de onderlinge afstemming is vormgegeven en op welke wijze in Nederland steeds is voorzien in parlementaire betrokkenheid. Geconcludeerd wordt dat de invloed van de EU de laatste jaren steeds belangrijker lijkt te worden. Eindconclusie is dat er op dit moment geen redenen zijn om de huidige werkwijze bij de voorbereiding van uitvoerende besluitvorming in internationaal en EU-verband te veranderen.
Het Staatsblad
Authors: Borman T.C. 
Published: October 2015

Het Staatsblad
Naar aanleiding van de pensionering van Sandra Slingerland, die bij het ministerie van Justitie 37 jaar lang verantwoordelijk was voor de uitgifte van het Staatsblad, worden in deze bijdrage enkele faits divers en petites histoires rond het Staatsblad behandeld. Ingegaan wordt op de historie van het uit 1813 daterende Staatsblad, inclusief de toepasselijke wetgeving. Verder wordt aandacht besteed aan voorvallen waarbij in het parlement het Staatsblad ter sprake kwam. Daarbij ging het onder meer over de toegankelijkheid, het formaat en de tijdige uitgifte van het Staatsblad.
Démonter/remonter le cinéma
Authors: Bellour Raymond 
Published: October 2015

Le cinéma a toujours éprouvé plus ou moins le désir ou le besoin de se citer lui-même. Mais il en va autrement quand l’oeuvre entière tombe sous le coup de la citation généralisée, au gré de stratégies variées par lesquelles se retournent l’une sur l’autre les logiques du cinéma et celles de l’art contemporain. Trois oeuvres emblématiques forment en cela une sorte de paradigme, qui ouvre sur bien d’autres : 24 Hours Psycho (1993) de Douglas Gordon; Histoire(s) du cinéma (1989-1998) de Jean-Luc Godard; The Clock (2010) de Christian Marclay. Dans l’oeuvre de Gordon, le corps du film est mis à mal par la transformation dont il devient l’objet, ralenti jusqu’au paradoxe pour un spectateur mué en visiteur improbable. Mais ce geste iconoclaste s’inscrit malgré lui dans la logique épistémique qui a été celle des analystes de films. Godard, à l’opposé, conçoit une ode au cinéma comme art pensé dans son histoire et son rapport aux autres arts. Elle culmine à travers l’hommage à Hitchcock dans l’épisode Le contrôle de l’univers. Quant à Marclay, le paradoxe des vingt-quatre heures de son montage généralisé devenant le temps réel de son spectateur-visiteur réalise comme une sortie du cinéma sous couvert d’en emprunter la matière et d’en mimer le dispositif.
Epidemiological evidence on extra-medical use of prescription pain relievers: transitions from newly incident use to dependence among 12–21 year olds in the United States using meta-analysis, 2002–13
Authors: Parker Maria A. , Anthony James C. 
Published: October 2015

Background.When 12-to-21-year-olds start using prescription pain relievers extra-medically, some of them transition into opioid dependence within 12 months after such use. Our main aim for this epidemiological research on 12-to-21-year-olds in the United States (US) is to estimate the risk of becoming a newly incident case of opioid dependence within 12 months after onset of using prescription pain relievers extra-medically (EMPPR).Methods.Meta-analyses from multiple independent replication samples now are possible, based upon nationally representative survey samples of US adolescents age 12–21 years. All 12-to-21-year-olds were sampled and recruited for the US National Surveys on Drug Use and Health, with standardized assessments of EMPPR use and opioid dependence (NSDUH, 2002–2013).Results.Peak risk for a transition from start of EMPPR use to opioid dependence within 12 months is seen at mid-adolescence among 14-to-15-year-olds (6.3%, 8.7% per year), somewhat earlier than peak risk for starting EMPPR use (seen for 16-to-19-year-olds at 4.1%, 5.9% per year). Applied to 12-to-21-year-olds in the US between 2002–2013, an estimated 8 million started using PPR extra-medically. Each year, roughly 42,000 to 58,000 transitioned into opioid dependence within 12 months after onset of such use.Discussion.These epidemiological estimates for the US in recent years teach us to expect one transition into adolescent-onset opioid dependence within 12 months for every 11–16 newly incident EMPPR users, yielding perhaps 120 newly incident opioid dependent cases in need of practitioner attention or treatment services, each day of each year. This evidence can be used to motivate more effective public health prevention, outreach, and early intervention programs as might prevent or delay occurrence of EMPPR use and opioid dependence.
The importance of Harmattan surges for the emission of North African dust aerosol
Authors: Fiedler S. , Kaplan M. L. , Knippertz P. 
Published: October 2015

AbstractDust aerosol is important in the Earth system, but the relative impact of meteorological mechanisms on North African dust emission remains unclear. This study presents the first climatology of dust emission amounts associated with Harmattan surges (HSs), characterized by postfrontal strengthening of near‐surface winds. A new automated identification uses their strong isallobaric winds as an indicator for HSs in 32 years of ERA‐Interim reanalysis. Their impact on dust aerosol emission is estimated by combining the identified events with derived dust emissions. The estimate highlights that about one third of the total emission mass is associated with HSs. Spring shows the largest associated emissions of 30–50% of the monthly totals consistent with the largest number and duration of HSs. Regional emission contributions of up to 80% in the north coincide with the overall largest emission maxima in spring. The importance of HSs for dust emission implies that aerosol‐climate models need to accurately represent synoptic‐scale storms.
Increasing atmospheric water vapor and higher daily precipitation intensity over northern Eurasia
Authors: Ye Hengchun , Fetzer Eric J. , Wong Sun , Behrangi Ali , Yang Daqing , Lambrigtson Bjorn H. 
Published: October 2015

AbstractIncreasing daily precipitation intensity is strongly associated with increasing water vapor in the atmosphere over northern Eurasia based on this study of 35 years of daily precipitation, specific humidity, and air temperature observations at 152 stations. The apparently linear relationship is consistent across all four seasons at interannual and longer time scales, and holds after temperature variation have been controlled. The study further reveals that this relationship is accompanied by increases in precipitation totals from heavy events (above the 70th percentile) and decreases in light ones (below the 30th percentile). Results suggest that increased atmospheric water vapor is the direct link to more frequent intense events of precipitation and increased risk of flooding under a warming climate via increasing precipitation intensity.
Separator reconnection at the magnetopause for predominantly northward and southward IMF: Techniques and results
Authors: Glocer A. , Dorelli J. , Toth G. , Komar C. M. , Cassak P. A. 
Published: October 2015

AbstractIn this work, we demonstrate how to track magnetic separators in three‐dimensional simulated magnetic fields with or without magnetic nulls, apply these techniques to enhance our understanding of reconnection at the magnetopause. We present three methods for locating magnetic separators and apply them to 3‐D resistive MHD simulations of the Earth's magnetosphere using the Block‐Adaptive‐Tree Solar‐wind Roe‐type Upwind Scheme code. The techniques for finding separators and determining the reconnection rate are insensitive to interplanetary magnetic field (IMF) clock angle and can in principle be applied to any magnetospheric model. Moreover, the techniques have a number of advantages over prior separator finding techniques applied to the magnetosphere. The present work examines cases of high and low resistivity for two clock angles. We go beyond previous work examine the separator during Flux Transfer Events (FTEs). Our analysis of reconnection on the magnetopause yields a number of interesting conclusions: Reconnection occurs all along the separator even during predominately northward IMF cases. Multiple separators form in low‐resistivity conditions, and in the region of an FTE the separator splits into distinct branches. Moreover, the local contribution to the reconnection rate, as determined by the local parallel electric field, drops in the vicinity of the FTE with respect to the value when there are none.
Imaging the magmatic system of Mono Basin, California, with magnetotellurics in three dimensions
Authors: Peacock J. R. , Mangan M. T. , McPhee D. , Ponce D. A. 
Published: October 2015

AbstractA three‐dimensional (3‐D) electrical resistivity model of Mono Basin in eastern California, unveils a complex subsurface filled with zones of partial melt, fluid‐filled fracture networks, cold plutons, and regional faults. In 2013, 62 broadband magnetotelluric stations were collected in an array around southeastern Mono Basin from which a 3‐D electrical resistivity model was created with a resolvable depth of 35 km. Multiple robust electrical resistivity features were found that correlate with existing geophysical observations. The most robust features are two 300 ± 50 km3 near‐vertical conductive bodies (3–10 Ω m) that underlie the southeast and northeastern margin of Mono Craters below 10 km depth. These features are interpreted as magmatic crystal‐melt mush zones of 15 ± 5% interstitial melt surrounded by hydrothermal fluids and are likely sources for Holocene eruptions. Two conductive east dipping structures appear to connect each magma source region to the surface. A conductive arc‐like structure (< 0.9 Ω m) links the northernmost mush column at 10 km depth to just below vents near Panum Crater, where the high conductivity suggests the presence of hydrothermal fluids. The connection from the southernmost mush column at 10 km depth to below South Coulée is less obvious with higher resistivity (200 Ω m) suggestive of a cooled connection. A third, less constrained conductive feature (4–10 Ω m) 15 km deep, extending to 35 km is located west of Mono Craters near the eastern front of the Sierra Nevada escarpment and is coincident with a zone of sporadic, long‐period earthquakes that are characteristic of a fluid‐filled (magmatic or metamorphic) fracture network. A resistive feature (103–105 Ω m) located under Aeolian Buttes contains a deep root down to 25 km. The eastern edge of this resistor appears to structurally control the arcuate shape of Mono Craters. These observations have been combined to form a new conceptual model of the magmatic system beneath Mono Craters to a depth of 30 km.
Trends in mesospheric ice layers in the Northern Hemisphere during 1961–2013
Authors: Berger U. , Lübken F.‐J. 
Published: October 2015

AbstractThe MIMAS ice model is used to study the trend behavior of polar mesospheric clouds (PMCs) responding to long‐term changes in mesospheric temperatures at northern high latitudes for the summer period 1961–2013. This paper presents long‐term PMC variations in terms of ice water content (IWC) at northern high latitudes for monthly July averages that are compared to solar backscatter ultraviolet (SBUV) data available in the period 1979–2013. In general, good agreement is found between long‐term PMC variations from the model and from satellite observations. For example, both model and SBUV data show an increase in ice water content (IWC > 40 g km−2) in the latitude band 74°–82°N with significant IWC trends of 2.8 ± 2.1 g km−2/dec and 2.4 ± 2.0 g km−2/dec, respectively. Modeled trends in IWC are latitudinally dependent. For the entire period 1961–2013 no trend exists at midlatitudes (50°–60°N) but increases poleward to highly significant values of 4.4 ± 0.9 g km−2/dec in the latitude band 74°–82°N. The analysis of trends in extreme PMC events (IWC > 300 g km−2) shows a 23%/dec increase in occurrence frequency at 74°–82°N which is by far the largest trend of all PMC parameters. We discuss the statistical properties of PMC following an exponential distribution. We derive an analytic solution of ice growth from microphysics that allows calculation of ice particle radius as a function of background conditions. As a result, the thermal conditions near 83 km height, with a cooling of −0.58 ± 0.32 K/dec, mainly determine trends in IWC whereas cooling at lower heights, induced by stratospheric ozone, controls to a large extent the long‐term behavior of PMC altitudes.
Temporal intrailiac balloon occlusion for the treatment of intractable pelvic fracture hemorrhage
Authors: Ishida Kenichiro , Noborio Mitsuhiro , Shimahara Yumiko , Nishimura Tetsuro , Sogabe Taku , Ieki Yohei , Ehara Naoki , Sadamitsu Daikai 
Published: October 2015

CaseA 48‐year‐old schizophrenic man sustained multiple injuries following a fall. Unstable pelvic fractures were diagnosed in the emergency department. The patient's hemodynamic status was stabilized following bilateral internal iliac artery embolization using a gelatin sponge. However, recurrent bleeding and an expanding retroperitoneal hemorrhage occurred 1 h after transcatheter arterial embolization.OutcomeUsing temporal intrailiac balloon occlusion, with preperitoneal gauze packing, the patient's hemodynamic status was stabilized in the intensive care unit. No complications were observed following transcatheter arterial embolization and balloon occlusion.ConclusionsTemporary intrailiac balloon occlusion is a rapid and safe treatment for refractory pelvic hemorrhage, which can be administered simultaneously with other treatments including preperitoneal gauze packing and external fixation.
Enantioselective Addition of a 2‐Alkoxycarbonyl‐1,3‐dithiane to Imines Catalyzed by a Bis(guanidino)iminophosphorane Organosuperbase
Authors: Kondoh Azusa , Oishi Masafumi , Takeda Tadahiro , Terada Masahiro 
Published: October 2015

AbstractA chiral bis(guanidino)iminophosphorane catalyzes enantioselective addition reactions of a 1,3‐dithiane derivative as a pronucleophile. The chiral uncharged organosuperbase facilitates the addition of benzyloxycarbonyl‐1,3‐dithiane to aromatic N‐Boc‐protected imines to provide optically active α‐amino‐1,3‐dithiane derivatives, which are valuable versatile building blocks in organic synthesis.
Enantioselective Total Syntheses of (−)‐Rhazinilam, (−)‐Leucomidine B, and (+)‐Leuconodine F
Authors: Dagoneau Dylan , Xu Zhengren , Wang Qian , Zhu Jieping 
Published: October 2015

AbstractA divergent total synthesis of three structurally distinct natural products from imine 9 was accomplished through an approach featuring: 1) a Pd‐catalyzed decarboxylative cross‐coupling, and 2) heteroannulation of 9 with bromoacetaldehyde and oxalyl chloride to give tetrahydroindolizine 6 and dioxopyrrole 7, respectively. The former was converted into (−)‐rhazinilam, while the latter was converted into (−)‐leucomidine B and (+)‐leuconodine F. A substrate‐directed highly diastereoselective reduction of a sterically unbiased double bond by using a homogeneous palladium catalyst was developed. A self‐induced diastereomeric anisochronism (SIDA) phenomenon was observed for leucomidine B.
Ultrasonic atomization and polyelectrolyte complexation to produce gastroresistant shell–core microparticles
Authors: Dalmoro Annalisa , Sitenkov Alexander Y. , Lamberti Gaetano , Barba Anna Angela , Moustafine Rouslan I. 
Published: October 2015

ABSTRACTIn this study ultrasound‐assisted atomization technique was combined with two‐stages polyelectrolyte complexation to produce enteric shell–core microparticles encapsulating a non‐steroidal, anti‐inflammatory gastrolesive active ingredient indomethacin. In particular, a solution of the anionic biopolymer alginate, containing indomethacin, was sprayed in fine droplets which were complexed with a cationic (meth)acrylate copolymer, Eudragit®E 100, which, in turn, was complexed by the anionic copolymer Eudragit®L30D‐55. The first complexation stage was applied to achieve a high drug encapsulation efficiency; the second one to assure good gastroresistance feature. The novel protocol has been found more effective in terms of loading, encapsulation efficiency, and enteric properties duringin vitrorelease tests, than conventional procedures which involved alginate cross‐linking by charged ions. Furthermore ultrasonic atomization–polyelectrolytes complexation preparation approach was performed using mild conditions, aqueous solutions, in the absence of organic solvents and chemical cross‐linkers. © 2015 Wiley Periodicals, Inc. J. Appl. Polym. Sci.2016,133, 42976.
A Metal‐free Approach to 3‐Aryl‐3‐hydroxy‐2‐oxindoles by Treatment of 3‐Acyloxy‐2‐oxindoles with Diaryliodonium Salts
Authors: Li Xiaokang , Ni Wei , Mao Fei , Wang Wei , Li Jian 
Published: October 2015

AbstractA mild, metal‐free approach has been realized for the facile construction of highly valuable 3‐(hetero)aryl‐3‐hydroxy‐2‐oxindoles. Direct arylations of 3‐acyloxy‐2‐oxindoles with diaryliodonium salts as arylation reagents are implemented in the presence of K2CO3 at room temperature without using an organometallic promoter to deliver an array of 3‐(hetero)aryl‐3‐hydroxy‐2‐oxindoles in good yields.
Anger, problematic alcohol use, and intimate partner violence victimisation and perpetration
Authors: Sprunger Joel G. , Eckhardt Christopher I. , Parrott Dominic J. 
Published: October 2015

AbstractBackgroundAnger and problematic alcohol use have been established as individual risk factors for intimate partner violence (IPV) victimisation and perpetration, but it is unknown how these factors convey risk for IPV perpetration for men and women within the context of mutually violent relationships.HypothesesAnger and problematic alcohol use were hypothesised to mediate the association between IPV victimisation and perpetration for men and women, with direct and indirect influences from partner variables.MethodsHeterosexual couples (N = 215) at high‐risk for IPV completed questionnaires indexing trait anger, problematic alcohol use and extent of past‐year IPV perpetration and victimisation. An actor‐partner interdependence modelling (APIM) framework was used to evaluate these cross‐sectional data for two hypothesised models and one parsimonious alternative.ResultsThe best‐fitting model indicated that IPV victimisation showed the strongest direct effect on physical IPV perpetration for both men and women. For women, but not men, the indirect effect of IPV victimisation on physical IPV perpetration through anger approached significance. For men, but not women, the victimisation–perpetration indirect effect through problematic drinking approached significance.Implications for clinical practiceThe results suggest that anger and problem drinking patterns play different yet important roles for men and women in mutually violent relationships. Copyright © 2015 John Wiley & Sons, Ltd.