bluuebunny/crossref_metadata_2025_split huggingface dataset:
Emergence of Scholarship in theAmerican Journal of Occupational Therapy
Authors: Crepeau Elizabeth Blesedell , Wilson Linda H. 
Published: June 2013

AbstractWe undertook a content analysis of 192 American Journal of Occupational Therapy articles published from 1947 to 2010 to understand and explicate the emergence of scholarship within the profession. Scholarship includes scientific inquiry, empirical research, and other forms of inquiry. We identified and coded three aspects of the development of scholarship: argument, methodological rigor, and occupational focus. All three aspects increased over the evaluated period, during which substantial changes occurred in the profession’s practice and access to higher education. We see the development of scholarship as aligned with the claiming of the profession’s independence and voice.
User‐Friendly Universal and Durable Subcellular‐Scaled Template for Protein Binding: Application to Single‐Cell Patterning
Authors: Jang Jae‐Won , Collins John M. , Nettikadan Saju 
Published: June 2013

AbstractA new method for subcellular‐sized protein patterning on a SiOx substrate is demonstrated by dip‐pen nanolithography printed aldehyde‐terminated alkylsilane template. The aldehyde‐silane template is stable and durable; for example, subcellular scaled IgG protein array can be obtained using one‐year old aldehyde‐silane template. Moreover, single cell patterning is successfully carried out by extracellular material (ECM) protein microarray and nanoarray fabricated on an aldehyde‐silane template. With more than half of chance, single‐ or double‐cells are successfully attached on fibronectin protein nanoarrays in 21 × 21 μm 2 (7 × 7 dot array) and 42 × 42 μm2 (14 × 14 dot array). The fibronectin nanoarray with small area (21 × 21 μm2) shows the more rate of single cell attachment. Therefore, it is also demonstrated that cell patterning can be controlled by adjusting the nanostructure of ECM materials.
The burden of mortality with costs in productivity loss from occupational cancer in Italy
Authors: Binazzi Alessandra , Scarselli Alberto , Marinaccio Alessandro 
Published: June 2013

AbstractBackgroundThe costs of productivity loss due to occupational cancer mortality are rarely investigated. An estimate of occupational cancer deaths in Italy in 2006 and an approximation of the resultant costs from medical and non‐medical expenditures together with figures of remuneration lost are provided.MethodsOccupational cancer deaths, obtained from the application of the attributable fraction (AF) to mortality data (source: Italian National Institute of Statistics), were used to calculate the Potential Years of Life Lost (PYLLs), the Potential Years of Working Life Lost (PYWLLs) and the costs of the loss of productive life. The health care costs for any cancer was applied to the estimated number of occupational cancer cases to obtain the total cost.ResultsAround 8,000–8,500 deaths/year from occupational cancer are estimated to occur in Italy, corresponding to 170,000 PYLLs and more than 16,000 PYWLLs, leading to around 360,000,000 euros in indirect economic loss. Health care costs of occupational cancer are estimated at 456,000,000 euros.ConclusionsOccupational cancer is of major concern in terms of mortality and economic productivity loss. Preventive efforts in evaluating ongoing risks and current exposures are strongly recommended to health policy‐makers. Am. J. Ind. Med. 56:1272–1279, 2013. © 2013 Wiley Periodicals, Inc.
Customized high resolution CGH‐array for clinical diagnosis reveals additional genomic imbalances in previous well‐defined pathological samples
Authors: Vallespín Elena , Palomares Bralo María , Mori M. Ángeles , Martín Rubén , García‐Miñaúr Sixto , Fernández Luis , de Torres M. Luisa , García‐Santiago Fe , Mansilla Elena , Santos Fernando , M‐Montaño Victoria E. , Crespo M. Carmen , Martín Sol , Martínez‐Glez Victor , Delicado Alicia , Lapunzina Pablo , Nevado Julián 
Published: June 2013

AbstractHigh‐resolution array comparative genomic hybridization (aCGH) is a powerful molecular cytogenetic tool that is being adopted for diagnostic evaluation of genomic imbalances and study disease mechanisms and pathogenesis. We report on the design and use, of a custom whole‐genome oligonucleotide‐based array (called KaryoArray®v3.0; Agilent‐based 8 × 60 K) for diagnostic setting, which was able to detect new and unexpected rearrangements in 11/63 (∼17.5%) of previous known pathological cases associated with known genetic disorders, and in the second step it identified at least one causal genomic imbalance responsible of the phenotype in ∼20% of patients with psychomotor development delay and/or intellectual disability. To validate the array, first; we blindly tested 120 samples; 63 genomic imbalances that had previously been detected by karyotyping, FISH and/or MLPA, and 57 sex‐matched control samples from healthy individuals; secondly a prospective study of 540 patients with intellectual disabilities, autism spectrum disorder and multiple congenital anomalies were evaluated to confirm the utility of the tool. These data indicate that implementation of array technologies as the first‐tier test may reveal that additional genomic imbalances could co‐exist in patients with trisomies and classical del/dup syndromes, suggesting that aCGH may also be indicated in these individuals, at least when phenotype does not match completely with genotype. © 2013 Wiley Periodicals, Inc.
Hot compressed water extraction of polysaccharides from Ganoderma lucidum using a semibatch reactor
Authors: Matsunaga Yui , Wahyudiono  , Machmudah Siti , Sasaki Mitsuru , Goto Motonobu 
Published: June 2013

ABSTRACTGanoderma lucidum (G. lucidum) is a mushroom‐forming white rot fungus. Although not edible, it is grown commercially for use as a medicinal supplement. In this study, G. lucidum was utilized for the extraction of polysaccharides by hot compressed water at temperatures of 373–463 K and a pressure of 4.0 MPa using a semibatch system—a most effective method because water at high temperature and pressure behaves as a reaction medium with remarkable properties. Under these conditions, thermal softening of G. lucidum occurred, allowing the removal of the polysaccharides protecting other constituents in G. lucidum via hydrolysis. The main massed peaks of water‐soluble products were distributed at around 688–2638 m/z with a peak‐to‐peak mass difference of 162 m/z, consistent with the repeating unit of the glucans. On the basis of these results, this process is proposed as applicable to the isolation of polysaccharides from other types of biomass and may lead to an advanced plant biomass components extraction technology. © 2013 Curtin University of Technology and John Wiley & Sons, Ltd.
Defining the optimal approach to the patient with postradiation prostate‐specific antigen recurrence using outcome data from a prospective randomized trial
Authors: Kim Miranda B. , Chen Ming‐Hui , de Castro Mário , Loffredo Marian , Kantoff Philip W. , D'Amico Anthony V. 
Published: June 2013

BACKGROUNDOptimal management remains unknown following prostate‐specific antigen (PSA) failure when considering comorbidity and PSA kinetics at recurrence. In order to define randomized controlled trials (RCTs) that can address this issue, this study examined factors associated with the risk of death following PSA failure.METHODSOf 206 men randomized to RT with or without 6 months of androgen suppression therapy (AST), 108 sustained PSA failure and began AST when PSA approached 10 ng/mL and formed the study cohort. Cox regression multivariable analysis was used to determine factors associated with death following PSA failure.RESULTSAfter a median follow‐up of 10.3 years of 108 men with PSA failure, 64 (59%) died, with 22 (34%) dying of prostate cancer (PC). Increasing PSA velocity at recurrence was associated with a significant increase in the risk of death (adjusted hazard ratio, 1.21; 95% confidence interval, 1.02‐1.45; P = .03). Among men with no/minimal versus moderate/severe comorbidity, PC comprised 42% (20 of 48) versus 12.5% (2 of 16) of all deaths, respectively. Estimates of PC‐specific and all‐cause death were significantly higher when PSA velocity was greater than as compared with the median or less in men with no/minimal (P < .008) but not moderate/severe comorbidity (P > .15).CONCLUSIONSDespite unfavorable PSA kinetics at recurrence, unhealthy men may not benefit from AST; RCTs examining intermittent AST versus surveillance are needed. For healthy men with unfavorable PSA kinetics at recurrence, PC death rates are high despite AST, which warrants RCTs to evaluate the impact on death when adding agents that prolong survival in men with metastatic castration‐resistant PC to AST. Cancer 2013;119:3280–6. © 2013 American Cancer Society.
Long‐term outcomes for men with high‐risk prostate cancer treated definitively with external beam radiotherapy with or without androgen deprivation
Authors: Nguyen Quynh‐Nhu , Levy Lawrence B. , Lee Andrew K. , Choi Seungtaek S. , Frank Steven J. , Pugh Thomas J. , McGuire Sean , Hoffman Karen , Kuban Deborah A. 
Published: June 2013

BACKGROUNDMen with high‐risk prostate cancer are often thought to have very poor outcomes in terms of disease control and survival even after definitive treatment. However, results after external beam radiotherapy have improved significantly through dose escalation and the use of androgen deprivation therapy (ADT). This report describes long‐term findings after low‐dose (< 75.6 Gy) or high‐dose (≥ 75.6 Gy) external beam radiation, with or without ADT.METHODSThis analysis included 741 men with high‐risk prostate cancer (clinical classification ≥ T3, Gleason score ≥ 8, or prostate‐specific antigen level ≥ 20 ng/mL) treated with external beam radiotherapy at a single tertiary institution from 1987 through 2004. The radiation dose ranged from 60 to 79.3 Gy (median, 70 Gy); 295 men had received ADT for ≥ 2 years, and the median follow‐up time was 8.3 years.RESULTSThe 5‐ and 10‐year actuarial overall survival rates were significantly better for men treated with the higher radiation dose (no ADT plus ≥ 75.6 Gy, 87.3% and 72.0%, respectively; and ADT plus ≥ 75.6 Gy, 92.3% and 72%, respectively) (P = .0035). The corresponding 5‐ and 10‐year biochemical failure‐free survival rates were significantly better for patients treated with both ADT and higher radiation dose (82% and 77%, P < .0001). At 5 years, men who had not received ADT and had received radiation dose < 75.6 Gy had higher clinical local failure rates than those given ADT and radiation dose ≥ 75.6 Gy (24.2% versus 0%, P < .0001). The 10‐year symptomatic local failure rate was only 2% for all patients.CONCLUSIONSContrary to lingering historical perceptions, treatment of high‐risk prostate cancer with modern, high‐dose, external beam radiotherapy and ADT can produce better biochemical, clinical, and survival outcomes over those from previous eras. Specifically, symptomatic local failure is uncommon, and few men die of prostate cancer even 10 or more years after treatment. Cancer 2013;119:3265–71. © 2013 American Cancer Society.
Fuzzy chessboard clustering and artificial bee colony routing method for energy‐efficient heterogeneous wireless sensor networks
Authors: AlShawi I. S. , Yan L. , Pan W. , Luo B. 
Published: June 2013

SUMMARYEnergy is an extremely critical resource for battery‐powered wireless sensor networks (WSNs), thus making energy‐efficient protocol design a key challenging problem. However, uneven energy consumption is an inherent problem in WSNs caused by multi‐hop routing and many‐to‐one traffic pattern among sensors. In this paper, we therefore propose a new clustering method called fuzzy chessboard clustering (FFC), which is capable to overcome the bottleneck problem and addressing the uneven energy consumption problem in heterogeneous WSNs. We also propose an energy‐efficient routing method called artificial bee colony routing method (ABCRM) to find the optimal routing path for the heterogeneous WSNs. ABCRM seeks to investigate the problems of balancing energy consumption and maximization of network lifetime. To demonstrate the effectiveness of FCC‐ABCRM in terms of lessening end‐to‐end delay, balancing energy consumption, and maximization of heterogeneous network lifetime, we compare our method with three approaches namely, chessboard clustering approach, PEGASIS, and LEACH. Simulation results show that the network lifetime achieved by FCC‐ABCRM could be increased by nearly 25%, 45%, and 60% more than that obtained by chessboard clustering, PEGASIS, and LEACH, respectively. Copyright © 2013 John Wiley & Sons, Ltd.
A provable secure sealed‐bid multi‐attribute auction scheme under semi‐honest model
Authors: Shi Wenbo 
Published: June 2013

SUMMARYSecure electronic auction protocol attracts increasing attention in the field of information security research. A variety of secure electronic auction protocols have achieved a lot. However, those studies mainly focus on price‐based auction model. There are few literatures involving security issues of multi‐attribute e‐auction. In recent years, the existing literatures mainly focus on the winner determination problem of multi‐attribute auction, but research of multi‐attribute e‐auction just begin from the perspective of information security. The proposal intends to start with the multi‐attribute e‐auction protocol, explores the different results in the multi‐attribute auction model because of different bid structures, focuses on qualitative attribute‐based winner determination auction model, proposes a new qualitative attribute‐based sealed‐bid multi‐attribute auction scheme under semi‐honest model for the first time. According to the security analysis and computation comparison, it provides strong bid privacy, public verifiability, and reasonable computational cost. Copyright © 2013 John Wiley & Sons, Ltd.
An efficient method for loss performance modeling of hierarchical heterogeneous wireless networks
Authors: Yu Xue Yong , Zhu Hong Bo 
Published: June 2013

SummaryLoss performance modeling is important for the purpose of developing efficient dimensioning tools for large complicated networks. The performance modeling involves two challenging problems:(i) it is difficult to achieve in heterogeneous wireless networks, where different networks have different statistical characteristics in service and traffic models and (ii) capacity‐constrained femto‐macro overlay networks pose significant challenges due to the wide variety of bandwidth requirement of Internet services, the large number of femtocells overlaid by a macrocell, and the need for fast computations imposed by practical requirements of dynamic real‐time resource allocation. This paper proposes a new computationally efficient numerical method for the loss probability approximation in hierarchical heterogeneous wireless networks. Verified by simulations, the performance and accuracy of the proposed numerical method is evaluated in a two‐tier hierarchical cellular network and compared with an existing approximation method based on multidimensional Markov‐modulated Poisson process. Copyright © 2013 John Wiley & Sons, Ltd.
A downlink beamforming assisted by locally positioned communication devices
Authors: You Cheolwoo , Jung Young‐Ho , Cho Sunghyun 
Published: June 2013

SUMMARYRecently, multiple cell types with overlapping coverage have been deployed simultaneously to increase cellular network capacity. Cross‐tier interference is one of the key technical challenges in the use of this method. A simple and practical beamforming scheme assisted by locally positioned communication devices for the downlink of a multi‐cell wireless hierarchical cell structure system is proposed in this paper to maximize the capacity of the embedded small cell and simultaneously ensure minimal impact on the performance of existing macrocells. The locally positioned communication devices can be implemented with low complexity and at low cost and can continuously provide helpful and accurate information to base stations for the proper configuration of geographical cell coverage, allowing neighboring cells to cooperate effectively with each other. Simulation results verify that the proposed scheme can provide a significant gain over conventional systems not using the proposed algorithm. Copyright © 2013 John Wiley & Sons, Ltd.
Updating the US hydrologic classification: an approach to clustering and stratifying ecohydrologic data
Authors: McManamay Ryan A. , Bevelhimer Mark S. , Kao Shih‐Chieh 
Published: June 2013

ABSTRACTHydrologic classifications unveil the structure of relationships among groups of streams with differing streamflows and provide a foundation for drawing inferences about the principles that govern those relationships. Hydrologic classes provide a template to generalize hydrologic responses to disturbance and stratify research and management needs applicable to ecohydrology. We used a mixed‐modelling approach to create hydrologic classifications for the continental USA using three streamflow datasets, a reference dataset compiled under more strict traditional standards and two additional datasets compiled under more relaxed assumptions. A variety of models were applied to each dataset, and Bayes criteria were used to identify optimal models and numbers of clusters. Using only reference‐quality gauges, we classified 1715 stream gauges into 12 classes across the USA. By including more streamflow gauges (n = 2402 and 2618) of lesser reference quality in subsequent classifications, we observed minimal increases in dimensionality (i.e. multivariate space) at the expense of increasing uncertainty and outliers. Part of the utility of classification systems rests in their ability to classify new objects and stratify data by common properties. We constructed separate random forest models to predict hydrologic class membership on the basis of hydrologic indices or landscape variables. In addition, we provide an approach to assessing potential outliers due to hydrologic alteration based on class assignment. Departures from class membership due to disturbance take into account multiple hydrologic indices simultaneously; thus, classes can be used to determine if disturbed streams are functioning within the natural range of hydrologic variability. Published 2013. This article is a U.S. Government work and is in the public domain in the USA.
Source duration of stress and water‐pressure induced seismicity derived from experimental analysis of P wave pulse width in granite
Authors: Masuda Koji 
Published: June 2013

AbstractPulse widths of P waves in granite, measured in the laboratory, were analyzed to investigate source durations of rupture processes for water‐pressure induced and stress‐induced microseismicity. Water was injected into a dry granite sample under constant axial stress of about 70% of fracture strength and a confining pressure of 40 MPa. After the effects of event size and hypocentral distance were removed from observed pulse widths, the ratio of the scaled source durations of water‐pressure induced and stress‐induced microseismicity was 0.52. The difference in the scaled source durations between water‐pressure induced and stress‐induced microseismicity suggests that water‐pressure induced microseismicity involves a greater rupture velocity or a more equidimensional fault geometry than stress‐induced microseismicity. These results suggest that pulse width analysis of P waveforms can be used to distinguish water‐pressure induced events from those induced by regional stress and to characterize the faulting process.
New data from borehole strainmeters to infer lava fountain sources (Etna 2011–2012)
Authors: Bonaccorso A. , Currenti G. , Linde A. , Sacks S. 
Published: June 2013

AbstractIn January 2011, eruptive activity resumed at Etna producing a new phase with frequent lava fountain episodes until April 2012. In November 2011, the first two borehole strainmeters were installed, which detected negative strain changes (~0.15–0.8 μstrain) during the paroxysmal events. A Finite Element Model was set up to estimate accurately the tilt and volumetric strain, taking into account the real profile of the volcano and the elastic medium heterogeneity. The numerical computations indicated an elongated depressurizing source located at 0 km b.s.l., which underwent a volume change of ~2 × 106 m3 which is the most of the magma volume erupted, while a smaller remaining part is accommodated by the magma compressibility. This shallow source cannot accumulate large magma volumes and, thus, favors short‐term periodic eruptive events with a fairly constant balance between the refilling and the erupted magma.
Turkish Validation of the PICCOLO (Parenting Interactions with Children: Checklist of Observations Linked to Outcomes)
Authors: Bayoğlu Birgul , Unal Özlem , Elibol Fatma , Karabulut Erdem , Innocenti Mark S. 
Published: June 2013

ABSTRACTEarly positive parent–child interactions are important for child development. Intervention research focused on increasing positive parent–child interactions has demonstrated increases in desired parenting behaviors and improvements in child outcomes. Parent–child interaction research in Turkey has been limited because of the need for reliable and valid measures of parent–child interaction. The aim of this study was to explore the validity and reliability of a Turkish version of a psychometrically strong measure of parent–child interaction that was developed in the United States: the Parenting Interactions with Children: Checklist of Observations Linked to Outcomes (PICCOLO). Mother–child interactions during a free‐play situation were scored using the Turkish translation of the PICCOLO. The Turkish PICCOLO demonstrated good reliability and validity; as good as that demonstrated in the original English‐language PICCOLO psychometric study. The Turkish PICCOLO meets the criteria established for a tool that will facilitate parent–child interaction research in Turkeyand appears to be practical and functional in evaluating the quality of parent–child interaction.
Efficient Synthesis and Antioxidant Evaluation of 2‐Aryl‐3‐(Pyrimidin‐2‐yl)‐Thiazolidinones
Authors: Campos José C. , Gouvêa Daniela P. , Ribeiro Camila da S. , Dutra Filipe S. P. , Stefanello Francieli M. , Pereira Claudio M. P. , Cunico Wilson , Siqueira Geonir M. 
Published: June 2013

ABSTRACTIn the present study, we reported the efficient synthesis of 11 3‐(pyrimidin‐2‐yl)‐thiazolidinones in good yields using molecular sieve as the desiccant agent. In addition, we have evaluated the antioxidant capacity of the synthesized compounds by the 2,2‐diphenyl‐2‐picrylhydrazyl hydrate (DPPH•) and the 2,2‐azinobis(3‐ethylbenzothiazoline‐6‐sulfonic acid) diammonium salt (ABTS+•) radicals scavenging assay. Six compounds showed antioxidant activity towards DPPH• (EC50 between 16.13 and 49.94 µg/mL) and also demonstrated excellent activity regarding ABTS+• (TEAC: 10.32–53.52). These results showed that compounds 3‐(pyrimidin‐2‐yl)‐thiazolidinones may be easily synthesized by a less expensive procedure and could be a good starting point to the development of new antioxidant compounds. © 2013 Wiley Periodicals, Inc. J BiochemMol Toxicol 27:445‐450, 2013; View this article online at wileyonlinelibrary.com. DOI 10.1002/jbt.21506