bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of organizational culture on employee commitment in the Indian IT services sourcing industry
Authors: Messner Wolfgang 
Published: May 2013

PurposeAs clients of India's IT services providers continue to complain about knowledge loss caused by high attrition rates in their offshore delivery factories, the linkages between organizational culture and commitment of the Indian employee base are of interest to researchers as well as practitioners. This paper seeks to address these issues.Design/methodology/approachData was collected in the first half of 2012 through the ICCA™ appraisal framework from 291 Indian IT executives and managers working for two IT services sourcing provider organizations in Pune and Bangalore, India. To analyse the data, descriptive and inferential statistics were used together with multiple regression and confirmatory factor analysis.FindingsTaken together, this research makes several contributions. First, the results of data analysis exhibit that, among the organizational culture dimensions, in‐group collectivism and performance orientation are the antecedents with the biggest effect on employee commitment. Other culture dimensions show varying degree of positive and negative influence on employee commitment. Second, this paper contributes to the cross‐cultural generalizability discussion of employee commitment. The data analysis unveils a stronger correlation between affective and normative commitment in the Indian context as compared to other North American studies. Third, it supports suggestions put forward in other research that continuance commitment should be split into the two subfactors c/alternative and c/sacrifice.Practical implicationsIt is proposed that the Indian IT services sourcing industry should be adept at thinking about employee commitment from an organizational culture point of view.Originality/valueThe proposed model of this research posits and proves that employee commitment in an Indian IT services offshoring context is influenced by organizational culture.
Factors involved in intensive care unit mortality following medical retrieval: Identifying differences between intensive care unit survivors and non‐survivors
Authors: Visser Philip , Harriss Linton R , Hart Graeme K , Bohensky Megan , Sundaresan Lalitha , Kennedy Marcus 
Published: May 2013

AbstractObjectiveThe study aimed to determine factors related to ICU mortality in critically ill patients transferred by Adult Retrieval Victoria (ARV) medical staff. Patients who died in ICU after interhospital transfer were compared against those who survived.MethodsThis was a retrospective cohort study of ARV cases between 1 January 2009 and 30 June 2010. Retrieval data were linked with data from the ANZICS CORE APD (Australia and New Zealand Intensive Care Society Centre for Outcome and Resource Evaluation Adult Patient Database). Victoria Data Linkage (VDL) performed linkage of data. Data included demographic and clinical data obtained during transfer and clinical data recorded in ICU.ResultsOf the 601 cases transferred by ARV during the study period, 549 cases were eligible for linkage to 25 543 ANZICS APD case records for the same period. VDL matched 460 of these cases (83.8%). Mortality rate in the matched sample was 13.9%. Variables associated with mortality were: advanced age (odds ratios [OR] 1.02, 95% confidence interval [CI] 1.00–1.04, P = 0.02), principal referral problem cardiac (OR 1.84, 95%CI 1.02–3.32, P = 0.04), lower mean arterial blood pressure (OR 0.97, 95% CI 0.95–0.99, P = 0.005) and tachycardia (OR 1.02, 95% CI 1.00–1.03, P = 0.008) on arrival at destination hospital.ConclusionsAdvanced age, lower mean arterial blood pressure and tachycardia towards the completion of transfer were associated with increased ICU mortality in this population. Clinicians should be aware of the additional risk for cardiac patients.
Expressed Sequence Tags (ESTs) analysis of Tenebrio molitor larvae
Authors: Jeong Ji Eun , Kang Se Won , Hwang Hee Ju , Chae Sung‐Hwa , Patnaik Bharat Bhusan , Han Yeon Soo , Lee Jae Bong , Jo Yong Hun , Lee Bok Leul , Seog Dae‐Hyun , Lee Yong Seok 
Published: May 2013

AbstractTenebrio molitor has been seriously investigated as a model insect in elucidating Toll signaling pathway and related regulators of innate immunity. However, little is known with regards to the genomic information in T. molitor. In an attempt towards exploiting the rich transcriptomics data that would offer further insights into the study on insect immunity through potential screening of immune‐related genes in the model insect, we constructed a cDNA library (library titer = 5.0 × 105pfu/ml) of T. molitor larvae and analyzed expressed sequence tag (EST) sequences from 1056 clones. The base calling and quality check of obtained chromatogram files were performed by using the Phred program (trim_alt 0.05 (P‐score > 20). After removal of vector and 100 bp and less sequences, 1023 sequences were generated having an average insert size of 792 bp, including 160 clusters, 164 contigs and 387 singletons through clustering and assembling process using the TGI Clustering Tools (TGICL) package. The unique EST sequences were searched against the NCBI nr database by local BLAST (blastx, E < e−5) with 940 sequences showing significant hits. Subsequently, KOG (clusters of orthologous groups for eukaryotic complete genomes) analysis was conducted (blastx, E < e−10) towards prediction of transcriptomal functions, leading to the categorization of 638 genes. The majority of genes belonged to Z category (cytoskeleton‐related genes), R category (general function prediction), and C category (energy production and conversion related genes). These basic EST datasets and their bioinformatics analysis will be helpful in investigating the biological mechanism and molecular pathway related genes involved in innate immunity mechanisms of T. molitor.
Four new species of the linyphiid spider genus Arcuphantes (Araneae, Linyphiidae) from Korea
Authors: Seo Bo Keun 
Published: May 2013

AbstractFour new Arcuphantes species are described: Arcuphante longipollex n. sp., Arcuphante profundus n. sp., Arcuphante rarus n. sp. and Arcuphante trifidus n. sp. Descriptions, diagnoses and illustrations of these new species are provided.
Visco‐Elastic and Flow Properties of Gelatin from the Bone of Freshwater Fish (Cirrhinus mrigala)
Authors: Chandra M. V. , Shamasundar B. A. , Kumar P. Ramesh 
Published: May 2013

AbstractThe average yield of gelatin from the bone of freshwater fish (Cirrhinus mrigala) was 6.13%. The fluorescence spectra revealed maximum emission at 303 nm indicating the exposure of chromophores to bulk solvent. The amino acid profile of gelatin revealed a higher proportion of glycine and imino acids. The bloom strength of gelled gelatin was 159.8 g. The average molecular weight of fish bone gelatin was 281 kDa as determined by gel filtration technique. The dynamic oscillatory test of gelatin solution as a function of time and temperature revealed gelling and melting temperatures of 8.0 °C and 17.0 °C, respectively. The flow behavior of gelatin solution as a function of concentrations and temperatures revealed non‐Newtonian behavior with pseudo‐plastic phenomenon. The Herschel–Bulkley and Casson models were found suitable to study the flow behavior. The emulsion capacity (EC) of gelatin was inversely proportional to its concentration.
Computed tomographic colonography (CTC); colorectal cancer diagnosis with CTC in an Auckland population
Authors: Moore Helen , Dodd Nicholas 
Published: May 2013

AbstractAimTo determine the sensitivity of computed tomographic colonography (CTC) in the detection of colorectal cancer in our population and evaluate the reasons why these lesions may be missed on CTC.MethodsAll patients who underwent CTC in the 65‐month period from 1 January 2004 to 1 July 2009 were included in the analysis. Demographic data and CTC findings were recorded, according to the CT Colonography Reporting and Data System. Data were cross‐matched with the National Cancer Registry results for colorectal cancer cases between 1 January 2004 and 1 October 2009, 3 months longer to include any delayed diagnoses.ResultsThere were 2026 consecutive CTC patients, comprising 52.6% female, average age of 60 years; range 19–87. Approximately 84% were symptomatic. There were 45 confirmed colorectal cancers among this patient group in the National Cancer Registry during the relevant time period compared with 43 suspected cancers on CTC, giving a miss rate of 2 of 45, or 4.4%.ConclusionThe sensitivity of 95% for CTC in the detection of colorectal cancer compares favourably with the published national and international data.
pavo: an R package for the analysis, visualization and organization of spectral data
Authors: Maia Rafael , Eliason Chad M. , Bitton Pierre‐Paul , Doucet Stéphanie M. , Shawkey Matthew D. 
Published: May 2013

Summary

Recent technical and methodological advances have led to a dramatic increase in the use of spectrometry to quantify reflectance properties of biological materials, as well as models to determine how these colours are perceived by animals, providing important insights into ecological and evolutionary aspects of animal visual communication.

Despite this growing interest, a unified cross‐platform framework for analysing and visualizing spectral data has not been available. We introduce pavo, an R package that facilitates the organization, visualization and analysis of spectral data in a cohesive framework. pavo is highly flexible, allowing users to (a) organize and manipulate data from a variety of sources, (b) visualize data using R's state‐of‐the‐art graphics capabilities and (c) analyse data using spectral curve shape properties and visual system modelling for a broad range of taxa.

In this paper, we present a summary of the functions implemented in pavo and how they integrate in a workflow to explore and analyse spectral data. We also present an exact solution for the calculation of colour volume overlap in colourspace, thus expanding previously published methodologies.

As an example of pavo's capabilities, we compare the colour patterns of three African glossy starling species, two of which have diverged very recently. We demonstrate how both colour vision models and direct spectral measurement analysis can be used to describe colour attributes and differences between these species. Different approaches to visual models and several plotting capabilities exemplify the package's versatility and streamlined workflow.

pavo provides a cohesive environment for handling spectral data and addressing complex sensory ecology questions, while integrating with R's modular core for a broader and comprehensive analytical framework, automated management of spectral data and reproducible workflows for colour analysis.
Neonatal folate, homocysteine, vitamin B12 levels and methylenetetrahydrofolate reductase variants in childhood asthma and eczema
Authors: van der Valk R. J. P. , Kiefte‐de Jong J. C. , Sonnenschein‐van der Voort A. M. M. , Duijts L. , Hafkamp‐de Groen E. , Moll H. A. , Tiemeier H. , Steegers E. A. P. , Hofman A. , Jaddoe V. W. V. , de Jongste J. C. 
Published: May 2013

AbstractObjectivesTo assess the associations of folate, homocysteine and vitamin B12 levels of children at birth and their methylenetetrahydrofolate reductase (MTHFR) variants with asthma and eczema in childhood.MethodsThis study was embedded in a population‐based prospective cohort study (n = 2,001). Neonatal cord blood folate, homocysteine and vitamin B12 levels were measured, and MTHFR C677T and A1298C genotyped. Wheezing and physician‐diagnosed eczema were annually obtained by questionnaire until 4 years. At 6 years, we collected information on physician‐diagnosed asthma ever and self‐reported eczema ever, measured fractional exhaled nitric oxide (FeNO), and interrupter resistance (Rint). Data were analysed with generalized estimating equations or logistic regression: continuous outcomes with linear regression models.ResultsFolate, homocysteine and vitamin B12 levels of children at birth were not associated with wheezing or eczema until 4 years, asthma and eczema ever, or FeNO or Rint at 6 years. In children carrying C677T mutations in MTHFR, higher folate levels were associated with an increased risk of eczema (repeated eczema until 4 years: OR 1.40 (95% CI 1.09–1.80) (SD change) P‐interaction = 0.003, eczema ever at 6 years: OR 1.41 (0.97–2.03) P‐interaction = 0.011). No interactions between MTHFR and child folate and homocysteine levels were observed for wheezing and asthma.ConclusionsFolate, homocysteine and vitamin B12 levels of children at birth did not affect asthma‐ and eczema‐related outcomes up to the age of 6 years. Further studies are warranted to establish the role of MTHFR variants in these associations.
Transition metal sensing by Toll‐like receptor‐4: next to nickel, cobalt and palladium are potent human dendritic cell stimulators
Authors: Rachmawati Dessy , Bontkes Hetty J. , Verstege Marleen I. , Muris Joris , von Blomberg B. Mary E. , Scheper Rik J. , van Hoogstraten Ingrid M. W. 
Published: May 2013

SummaryBackground Nickel was recently identified as a potent activator of dendritic cells through ligating with human Toll‐like receptor (TLR)‐4.Objectives Here, we studied an extended panel of transition metals neighbouring nickel in the periodic table of elements, for their capacity to activate human monocyte‐derived dendritic cells (MoDCs).Methods The panel included chromium, cobalt, and palladium, all of which are known to be frequent clinical sensitizers. MoDC activation was monitored by assessment of release of the pro‐inflammatory mediator interleukin (IL)‐8, a major downstream result of TLR ligation.Results The data obtained in the present study show that cobalt and palladium also have potent MoDC‐activating capacities, whereas copper and zinc, but not iron and chromium, have low but distinct MoDC‐activating potential. Involvement of endotoxin contamination in MoDC activation was excluded by Limulus assays and consistent stimulation in the presence of polymyxin B. The critical role of TLR4 in nickel‐induced, cobalt‐induced and palladium‐induced activation was confirmed by essentially similar stimulatory patterns obtained in an HEK293 TLR4/MD2 transfectant cell line.Conclusions Given the adjuvant role of costimulatory danger signals, the development of contact allergies to the stimulatory metals may be facilitated by signals from direct TLR4 ligation, whereas other metal sensitizers, such as chromium, may rather depend on microbial or tissue‐derived cofactors to induce clinical sensitization.
New UK nickel‐plated steel coins constitute an increased allergy and eczema risk
Authors: Julander Anneli , Midander Klara , Herting Gunilla , Thyssen Jacob P. , White Ian R. , Odnevall Wallinder Inger , Lidén Carola 
Published: May 2013

SummaryBackgroundNickel‐plated steel coins have recently been introduced in the United Kingdom.ObjectivesTo compare the performance and allergy risk of the new nickel‐plated coins (five and ten pence) with those of the cupro‐nickel coins being replaced.Materials and methodsCoin handling studies with assessment of skin exposure and metal release in artificial sweat were performed. Six volunteers participated.ResultsThe amount of nickel deposited onto skin during the handling of nickel‐plated coins for 1 hr was 7.5 µg/cm2, four times higher than that from cupro‐nickel coins. The nickel content in the oxidized surface of nickel‐plated coins was higher, explaining the higher skin dose. Initial nickel release rates were 10–27 times higher than 1‐week rates, emphasizing that brief and repeated contact results in significant nickel exposure.ConclusionsNickel‐plated coins deposit higher levels of nickel onto skin than cupro‐nickel coins, and hence pose an increased allergy risk. One‐week release in artificial sweat is not suitable for determining the risk of handling items with high nickel release that come into short, repeated contact with the skin. The nickel skin dose is recommended for risk assessment. UK citizens are now, because of this change in coinage, unnecessarily exposed to higher levels of nickel on the skin. This is of public health concern.
Character comparison of abdomen‐derived and eyelid‐derived mesenchymal stem cells
Authors: Kim S.‐H. , Bang S. H. , Park S. A. , Kang S. Y. , Park K. D. , Oh I. U. , Yoo S. H. , Kim H. , Kim C.‐H. , Baek S. Y. 
Published: May 2013

AbstractObjectivesWhile most human adipose tissues, such as those located in the abdomen, hip and thigh, are of mesodermal origin, adipose tissues located in the face are of ectodermal origin. The present study has compared stem cell‐related features of abdomen‐derived adult stem cells (A‐ASCs) with those of eyelid‐derived adult stem cells (E‐ASCs).Materials and methodsAdipose tissue‐derived cells were maintained in DMEM supplemented with 10% FBS. Before passage 6, cells were analysed using FACS, immunocytochemistry and quantitative real time PCR (qRT‐PCR). To examine multi‐differentiational potential, early passage ASCs were cultivated in each of a commercial Stempro® Differentiation kit.ResultsUnlike fibroblast‐like morphology of A‐ASCs, E‐ASCs had bipolar morphology. Both types of cell exhibited similar surface antigens, and neuronal cell‐related genes and proteins. However, there were differences in mRNA expression levels of CD90 and CD146; neuron‐specific enolase (NSE) and nuclear receptor‐related protein 1 (Nurr1) were different between the two cell types. There was no difference in multi‐differentiational potential between 3 E‐ASCs lines, however, E‐ASCs had higher expression levels of chondrocyte‐related genes compared to A‐ASCs. These cells underwent senescence and maintained normal karyotypes.ConclusionsAlthough isolated from similar adipose tissues, both types of cells displayed many contrasting characteristics. Understanding defining phenotypes of such cells is useful for making suitable choices in differing clinical indications.
Low‐intensity pulsed ultrasound induced enhanced adipogenesis of adipose‐derived stem cells
Authors: Fu N. , Yang X. , Ba K. , Fu Y. , Wei X. , Yue Y. , Li G. , Yao Y. , Chen J. , Cai X. , Liang C. , Ge Y. , Lin Y. 
Published: May 2013

AbstractObjectiveThe aim of this study was to investigate effects of low‐intensity pulsed ultrasound (LIPUS) on differentiation of adipose‐derived stem cells (ASCs), in vitro.Materials and methodsMurine ASCs were treated with LIPUS for either three or five days, immediately after adipogenic induction, or delayed for 2 days. Expression of adipogenic genes PPAR‐γ1, and APN, was examined by real‐time PCR. Immunofluorescence (IF) staining was performed to test for PPAR‐γ at the protein level.ResultsOur data revealed that specific patterns of LIPUS up‐regulated levels of both PPAR‐γ1 and APN mRNA, and PPAR‐γ protein.ConclusionsIn culture medium containing adipogenic reagents, LIPUS enhanced ASC adipogenesis.
Late effects of childhood cancer treatment: severe hypertriglyceridaemia, central obesity, non alcoholic fatty liver disease and diabetes as complications of childhood total body irradiation
Authors: Rajendran R. , Abu E. , Fadl A. , Byrne C. D. 
Published: May 2013

AbstractBackgroundChildhood cancer survivors may develop a number of endocrine complications linked to organ failure, such as hypogonadism, diabetes and growth hormone deficiency. However, increasing evidence now suggests that total body irradiation treatment, specifically, is linked with future risk of insulin resistance, hepatic steatosis and dyslipidaemia, possibly because total body irradiation affects adipocyte differentiation and impairs subcutaneous adipose tissue depot expansion during times of positive energy balance.Case reportWe describe a 20‐year‐old woman who developed pancreatitis with severe hypertriglyceridaemia (serum triglycerides > 300 mmol/l) that required plasmapheresis. She had received total body irradiation prior to her bone marrow transplant at age 6 years for relapsed acute lymphoblastic leukaemia. She developed ovarian failure at age 12 years. At age 15 years she was noted to have hyperglycaemia, increased blood pressure, hepatic steatosis and mild hypertriglyceridaemia. She presented with severe hypertriglyceridaemia and eruptive xanthoma, and developed pancreatitis 12 h after admission. She was treated with plasmapheresis and intravenous insulin and made an excellent recovery. We implicate and discuss total body irradiation as the major contributing factor to her severe hypertriglyceridaemia, compounded by worsening glycaemic control, oestrogen deficiency and a changing adult lifestyle.ConclusionChildren who have received total body irradiation are at risk of diabetes and an exaggerated form of the metabolic syndrome with hypertriglyceridaemia, which can be life‐threatening. We suggest that survivors of total body irradiation treatment require careful lifelong monitoring of their metabolic status.
Breastfeeding in women with diabetes: lower rates despite greater rewards. A population‐based study
Authors: Finkelstein S. A. , Keely E. , Feig D. S. , Tu X. , Yasseen A. S. , Walker M. 
Published: May 2013

AbstractAimsTo explore intention to breastfeed and breastfeeding rates in hospital and on discharge across women with pre‐gestational or gestational diabetes mellitus, or no diabetes.MethodsA retrospective cohort analysis was conducted using data from four Ontario hospitals. Women who delivered a viable infant between 1 April 2008 and 31 March 2010 were included in the study. Unadjusted and adjusted odds ratios were calculated for each outcome measure and were used to compare the breastfeeding rates among women with and without diabetes.ResultsAfter controlling for potential confounders, women with insulin‐treated diabetes were less likely to intend to breastfeed, when compared with women without diabetes (adjusted odds ratio 0.49, 95% CI 0.27–0.89). In hospital, women with insulin‐treated diabetes were least likely to breastfeed (odds ratio 0.42, 95% CI 0.26–0.67), followed by women with non‐insulin‐treated diabetes (odds ratio 0.50, 95% CI 0.26–0.96) and women with gestational diabetes (odds ratio 0.77, 95% CI 0.68–0.87) when compared with women without diabetes. On discharge, women with insulin‐treated diabetes were least likely to breastfeed (odds ratio 0.38, 95% CI 0.24–0.60), followed by women with gestational diabetes (odds ratio 0.75, 95% CI 0.66–0.85); rates of breastfeeding among women with non‐insulin‐treated diabetes were comparable on discharge with those of women without diabetes. Women seeking care from an antenatal provider other than a physician were 2–3 times more likely to breastfeed in hospital and on discharge.ConclusionsWomen with insulin‐treated diabetes had the poorest outcomes with respect to breastfeeding rates. Gestational and non‐insulin‐treated diabetes were associated with lower rates of breastfeeding in hospital, while gestational diabetes was additionally associated with lower breastfeeding rates on discharge.