bluuebunny/crossref_metadata_2025_split huggingface dataset:
The relationship between complete blood cell count-derived inflammatory biomarkers and benign prostatic hyperplasia in middle-aged and elderly individuals in the United States: Evidence from NHANES 2001–2008
Authors: Shi Chengdong , Cao Hongliang , Zeng Guoqiang , Yang Lei , Wang Yuantao 
Published: July 2024

Background
Benign prostatic hyperplasia (BPH) is a common health disorder of the male genitourinary system with a high prevalence, especially among middle-aged and older adults, which seriously affects men’s quality of life. Inflammatory markers derived from complete blood cell count (CBC) have previously been considered a prognostic indicator for various diseases, but little is known about their relationship with BPH. This study evaluated the relationship between complete blood cell count (CBC)-derived inflammatory biomarkers and BPH.

Methods
Data for this cross-sectional study were gathered from the National Health and Nutrition Examination Survey (NHANES) between 2001 and 2008. Using multiple logistic regressions, the study examined the association between benign prostatic hyperplasia(BPH) and Inflammatory biomarkers derived from blood cell counts such as neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), monocyte-to-lymphocyte ratio (MLR), Systemic Inflammatory Response Index (SIRI) and Systemic Immunoinflammatory Index (SII).

Results
3,919 participants were included, with a median age of 61.00 (52.00–71.00) years old. Among them, 609 participants had benign prostatic hyperplasia, with a prevalence of 15.54%. Upon accounting for confounding factors, the study revealed a positive correlation between the plurality of BPH PLR and SII. However, MLR, NLR, and SIRI did not significantly correlate with the prevalence of BPH (p>0.05). In contrast to the lowest quartile, higher quartiles of PLR (OR = 1.93[1.38–2.69]) and SII (OR = 1.71[1.22–2.40]) were linked to an elevated risk of BPH. Interaction tests showed that age, body mass index, hypertension, diabetes, smoking, and drinking had no significant effect on this positive correlation (p for interaction>0.05). In addition, we found a roughly linear association between SII, PLR, and BPH using smoothed curve fitting.

Conclusions
According to our research, high levels of PLR and SII are positively linked with an increased risk of BPH in middle-aged and elderly individuals in the United States. The results compensate for previous studies that still need to be validated with larger prospective cohorts.
Outcomes of children with clear cell sarcoma of kidney following NWTS strategies in Shanghai China (2003–2021)
Authors: Zhang Anan , Yuan Xiaojun , Jiang Shayi , Xu Dongqing , Huang Can , Tang Jing yan , Gao Yijin 
Published: July 2024

Background
Although clear cell sarcoma of kidney (CCSK) is rare, it is the second most common renal tumor in children after Wilms’ tumor. NWTS and SIOP are two major groups which had made tremendous efforts on renal tumors, but the strategies are different, for NWTS follows the upfront surgery principle providing definite pathology and the SIOP follows the upfront chemotherapy principle, each has its own advantages. Here we aimed to evaluate the outcomes of CCSK in China following NWTS strategies to analyze the prognostic factors.

Methods
For this multicenter retrospective study, a total of 54 patients were enrolled from three children’s hospitals, between April 2003 and December 2021. Treatment comprised upfront radical nephrectomy, followed by radiotherapy and intensive chemotherapy. Clinical records were regularly updated. Prognostic factors and survival rates were evaluated.

Results
The 54 enrolled patients had a median age of 37 months (range, 4 months to 11.4 years). The stage distribution was 16% stage I (n = 9), 30% stage II (n = 16), 39% stage III (n = 21), and 15% stage IV (n = 8). Among stage IV, metastasis sites included the lung (n = 6), bone (n = 1), and intra-orbital/cervical lymph node (n = 1). After a median follow-up of 5.6 years, the 5-year event-free survival (EFS) was 82.4±5.4%, and overall survival was 88.1±4.6%. The EFS was 100% for stage I, 93.8 ±6.1% for stage II, 71.1±10.0% for stage III, and 68.6±18.6% for stage IV. Univariate analysis revealed that staging (III/IV), tumor rupture, and inferior vena cava tumor thrombus were inferior prognostic factors. Multivariate analysis revealed that tumor rupture was independent poor prognostic factor (P = 0.01, HR 5.9). Among relapsed patients, relapse occurred a median of 11 months after diagnosis (range, 4–41 months), and 50% (4/8) achieved a second complete remission after multiple treatment. None of the six lung metastasis patients received lung RT, only one patient developed a relapse and was salvaged by RT after relapse.

Conclusions
Tumor rupture was independent poor prognostic factor. Upfront surgery of NWTS strategies can make a definite pathology diagnosis, but how to reduce tumor rupture during surgery is important especially in developing countries. The outcomes of patients with stage I–III CCSK in China were comparable to findings in other developed countries. Better outcomes were achieved in stage IV CCSK by using an intensive chemotherapy regimen including carboplatin, which require further confirmation by AREN0321. Lung RT may be safely omitted in selected patients who achieve a compete radiographic response after 6 weeks of systemic treatment (including surgery). Treatment should be encouraged even in CCSK cases with metastasis and relapse.
Moving object detection via feature extraction and classification
Authors: Li Yang 
Published: July 2024

Abstract
Foreground segmentation (FS) plays a fundamental and important role in computer vision, but it remains a challenging task in dynamic backgrounds. The supervised method has achieved good results, but the generalization ability needs to be improved. To address this challenge and improve the performance of FS in dynamic scenarios, a simple yet effective method has been proposed that leverages superpixel features and a one-dimensional convolution neural network (1D-CNN) named SPF-CNN. SPF-CNN involves several steps. First, the coined Iterated Robust CUR (IRCUR) is utilized to obtain candidate foregrounds for an image sequence. Simultaneously, the image sequence is segmented using simple linear iterative clustering. Next, the proposed feature extraction approach is applied to the candidate matrix region corresponding to the superpixel block. Finally, the 1D-CNN is trained using the obtained superpixel features. Experimental results demonstrate the effectiveness of SPF-CNN, which also exhibits strong generalization capabilities. The average F1-score reaches 0.83.
Physicochemical model of uranium hexafluoride (UF6) radiolysis under action of alpha particles
Authors: Danshin Artem A. , Kovalishin Alexey A. 
Published: July 2024

Abstract
A multiscale model describing the kinetics of the processes taking place during the radiolysis of uranium hexafluoride (UF6) has been developed using fundamental physical and chemical principles. The model incorporates both the radiolysis and thermal terms. The processes of the radiolysis products release from the gas phase to the solid and vice versa are taken into account. The predictions of the model are verified against the available experimental data.
Application of ultrasound-guided thoracic paravertebral block or intercostal nerve block for acute herpes zoster and prevention of post-herpetic neuralgia: A case–control retrospective trial
Authors: Xue Mianrong , Yuan Rong , Yang Yanwei , Qin Zhenlong , Fu Runqiao 
Published: July 2024

Abstract

Objectives
Ultrasound (US)-guided intercostal nerve block (ICNB) is an easier approach with a very low incidence of complications for different surgeries; nevertheless, only a few studies estimate the effect of ICNB for acute HZ. To explore the US-guided ICNB for management of herpes zoster (HZ)-related acute pain and possible prophylaxis for post-herpetic neuralgia (PHN) taking the conventional thoracic paraverteral block (TPVB) as control.

Methods
A total of 128 patients with HZ were retrospectively stratified into antiviral treatment (AVT) plus US-guided TPVB (TPVB group), AVT plus US-guided ICNB (ICNB group) or AVT alone (control group) based on the treatment they received. HZ-related illness burden (HZ-BOI) over 30 days after inclusion as the primary endpoint was determined by a severity-by-duration composite pain assessment. Rescue analgesic requirement, health-related quality of life, PHN incidence, and adverse events were also recorded.

Results
Significantly lower HZ-BOI scores within post-procedural 30 days using the area under the curve were reported with TPVB and ICNB compared with the control group: mean difference of 57.5 (p < 0.001) and 40.3 (p = 0.003). No difference was reported between TPVB and ICNB (p = 1.01). Significant greater improvements in PHN incidence, EQ-5D-3L scores, and rescue analgesic requirements were observed during follow-up favoring two trial groups, while comparable between two trial groups. No serious adverse events were observed.

Conclusions
US-guided ICNBs were as effective as TPVBs for acute HZ. The ICNB technique was an easier and time-efficient approach as opposed to conventional TPVB, which might be encouraged as a more accessible preemptive mean for preventing PHN.
Spectral reconstruction using neural networks in filter-array-based chip-size spectrometers
Authors: Wissing Julio , Fargueta Lidia , Scheele Stephan 
Published: July 2024

Abstract
Spectral reconstruction in filter-based miniature spectrometers remains challenging due to the ill-posed nature of identifying stable solutions. Even minor deviations in sensor data can cause misleading reconstruction outcomes, particularly in the absence of proper regularization techniques. While previous research has attempted to mitigate this instability by incorporating neural networks into the reconstruction pipeline to denoise the data before reconstruction or correct it after reconstruction, these approaches have not fully resolved the underlying issue. This work functions as a proof-of-concept for data-driven reconstruction that relies exclusively on neural networks, thereby circumventing the need to address the ill-posed inverse problem. We curate a dataset holding transmission spectra from various colored foils, commonly used in theatrical, and train five distinct neural networks optimized for spectral reconstruction. Subsequently, we benchmark these networks against each other and compare their reconstruction capabilities with a linear reconstruction model to show the applicability of cognitive sensors to the problem of spectral reconstruction. In our testing, we discovered that (i) spectral reconstruction can be achieved using neural networks with an end-to-end approach, and (ii) while a classic linear model can perform equal to neural networks under optimal conditions, the latter can be considered more robust against data deviations.
La posture du corps professoral à l’égard de l’implantation d’une nouvelle politique de reconnaissance des acquis des compétences (RAC) et de l’expérience (RAE) pour les programmes de formation à l’enseignement
Authors: El Euch Sonia 
Published: July 2024

La posture du corps professoral à l’égard des reconnaissances d’acquis de compétences (RAC) et d’expérience (RAE) pour les programmes de formation à l’enseignement est floue. Une étude a été effectuée pour décrire cette posture et rendre compte des facteurs explicatifs. Les résultats obtenus auprès de quelque 175 membres du corps professoral œuvrant en formation à l’enseignement dans les Facultés ou Départements des sciences de l’éducation au Québec révèlent une réticence à adhérer à la RAC/RAE pour la formation à l’enseignement malgré un accord avec le principe de RAC/RAE. Les facteurs influençant l’acceptation ou la résistance à la RAC/RAE ont été explorés à travers un questionnaire et sont présentés dans cet article.
Quelques propos recueillis lors d’un entretien sur la reconnaissance des acquis à l’université
Authors: Laurin Daniel 
Published: July 2024

Le Bureau de coopération interuniversitaire (BCI) a été mandaté en 2018 par le ministère de l’Enseignement supérieur (MES) afin de collaborer avec les universités pour l’avancement du dossier de la reconnaissance des acquis (RA) universitaire au Québec. Daniel Laurin, conseiller-expert en reconnaissance et en validation des acquis (RVA) au BCI, a été interviewé par Jean Pascal Lafrance en mars 2023 dans le cadre de la préparation de ce numéro spécial sur la reconnaissance et la validation des acquis expérientiels (RVAE) à l’université.
The Parmesan Pie (Part Two)
Authors: Martellotti Anna 
Published: July 2024

This is the second and final instalment of the the article by the author which appeared in Issue 59, which provides a history of a dish -- Torta Parmesana -- which originated in ancient mesopotamia. In this second part, the author examines how what was originally a magnificent and ostentatious dish was simplified and became widespread through Italy.
The translation of the essay into English was done by Christopher Williams, who deserves our thanks and those of our readers for this valuable service.
Árvores Comuns de Moçqambique. Common Trees of Mozambique
Authors: Keller Harold W. 
Published: July 2024

Mozambique is a country located in southeastern Africa bordered by the Indian Ocean to the east Tanzania to the north, Malawi and Zambia to the northwest, Zimbabwe to the west, and Eswatini and South Africa to the southwest. A colored map on page 12 shows the location of the country. There are 53 families and 153 genera included in the descriptions and illustrations. The species names are given in English and Portuguese. Each taxon is represented by one description page and one color illustration page. Species descriptions are in both English and Portuguese organized by DISTRIBUTION, HABITAT, USES, and NOTES. This book will have limited use outside of the geographical area of emphasis. The Glossary, Bibliography, Index of Local Names, and General Index add value to book usage.
Reviewing China’s Unequal Education System Based on Ecological System Theory
Authors: Wang Xining , McGuckin Conor , Zhang Chengming 
Published: July 2024

This review examines China’s educational system the “two-track system” and rural education challenges through the lens of Bronfenbrenner's Ecology System Theory. Using a theoretical framework to review related literature can support readers in understanding the intricate interplay between societal factors, cultural influences, policy decisions, and specific issues. Therefore, this aims to understand how the ecological environment shapes rural education’s development until today, and the Ecological System Theory is used as a theoretical guidance. To find the potential answer to proposed research questions (RQ): RQ 1. What is the background of rural China and the "two-track system" of education? RQ 2. What is the difference between China's urban education and rural education? RQ 3. How does the related environment influence China's educational system? By addressing this fundamental issue, a comprehensive review is provided by following the ecology system theory from the macro-system level to the micro-system
MMR status of colorectal carcinomas at a tertiary cancer care centre in Central India
Authors: Pangarkar Meena , Das Satabdi , Pagey Radhika , Deulkar Shweta , Mahindra Shraddha , Devi Yogita , Pathak Anand 
Published: July 2024

Microsatellite instability (MSI) and mismatch repair (MMR) deficiency are important biomarkers in colorectal cancer (CRC) that have clinical implications for patient management and treatment. MMR deficiency can lead to MSI, which is characterized by alterations in the length of microsatellite DNA sequences. Clinical applications of MMR deficiency in colorectal adenocarcinoma are as a prognostic marker as well as Predictive marker for adjuvant chemotherapy and immunotherapy. To assess the MMR status of colorectal adenocarcinomas.: This was a retrospective study of 127 colorectal adenocarcinomas cases. All the samples were either biopsies or surgically resected tumor tissues from patients of Carcinoma Colon and rectum. Immunohistochemistry was performed on Roche Ventana Benchmark XT autostainer.: MLH-1, PMS2, MSH2 and MSH6 expression was retained in the tumor cells in 106 cases and it was lost in 21 cases. Among various clinicopathological variables, tumor site and AJCC pStage were found to be significantly associated with dMMR tumors. Patients of colorectal adenocarcinomas were benefited by MMR testing as it influenced the adjuvant treatment in all Stage IIA cases as well as all metastatic cases. Incorporating MMR testing into routine clinical practice can help optimize patient management and treatment strategies in CRC.
The Predictors of Surgery for Symptomatic, Atraumatic Full-Thickness Rotator Cuff Tears Change Over Time
Authors: Kuhn John E. , Dunn Warren R. , Sanders Rosemary , Baumgarten Keith M. , Bishop Julie Y. , Brophy Robert H. , Carey James L. , Holloway Brian G. , Jones Grant L. , Ma C. Benjamin , Marx Robert G. , McCarty Eric C. , Poddar Sourav K. , Smith Matthew V. , Spencer Edwin E. , Vidal Armando F. , Wolf Brian R. , Wright Rick W. 
Published: July 2024

Background:
A prospective cohort study was conducted to assess the predictors of failure of nonoperative treatment, defined as the patient undergoing surgery for symptomatic, atraumatic full-thickness rotator cuff tears. We present the 10-year follow-up data of this population to determine if predictors for surgery change over time, and secondarily we report the outcomes of the cohort.

Methods:
At the time of enrollment, demographic, symptom, rotator cuff anatomy, and patient-reported outcome data were collected in patients with symptomatic, atraumatic full-thickness rotator cuff tears. Patients underwent a standard physical therapy protocol for 6 to 12 weeks. Patient data were then collected at 1, 2, 5, 7, and 10 years. Failure of nonoperative treatment was defined as the patient electing to undergo surgery.

Results:
Of the 452 patients in the original cohort, 20 patients (5%) withdrew from the study, 37 (9%) died before 10 years, and 40 (9%) were otherwise lost to follow-up. A total of 115 patients (27.0%) underwent a surgical procedure at some point during the 10-year follow-up period. Of these patients, 56.5% underwent surgery within 6 months of enrollment and 43.5%, between 6 months and 10 years. Low patient expectations regarding the efficacy of physical therapy were found to be a predictor of early surgery. Workers’ Compensation status and activity level were more important predictors of later surgery. Patient-reported outcome measures all improved following physical therapy. For patients who did not undergo a surgical procedure, patient-reported outcome measures did not decline over the 10-year follow-up period.

Conclusions:
Low patient expectations regarding the efficacy of physical therapy were found to be a predictor of early surgery, whereas Workers’ Compensation status and activity level were predictors of later surgery. Physical therapy was successful in >70% of patients with symptomatic, atraumatic full-thickness rotator cuff tears at 10 years. Outcome measures improved with physical therapy and did not decline over the 10-year follow-up period.

Level of Evidence:
Prognostic Level I. See Instructions for Authors for a complete description of levels of evidence.
The Early Determination Method of Reservoir Drive of Oil Deposits Based on Jamalbayli Indexes
Authors: Jamalbayov Mahammad Asaf , Yildirim Betul , Abdullazada Atilla 
Published: July 2024

Summary
Historically, the concept of “reservoir drive” aimed to simplify the mathematical modeling in reservoir engineering. Within this framework, the energy of the reservoir, particularly its aquifer, was idealized, leading to classifications such as “partial waterdrive,” “full waterdrive,” “gas cap drive,” and so forth. However, in reality, all existing energy sources interact simultaneously within reservoirs. Accordingly, this study aims to develop a new concept for a more realistic description of reservoir drive mechanisms and evaluation of reservoir energy performance. Numerous computer simulations have revealed a strong correlation between the ratio of relative changes in pore volume to relative changes in reservoir pressure and the reservoir’s energy nature and activity level. Moreover, the noted ratio did not depend on production technology, pressure/volume/temperature properties of hydrocarbon systems, rheological properties of reservoir rocks, or other factors. Based on this correlation, specific parameters termed as Jamalbayli Indexes (JI) have been identified to quantitatively describe reservoir energetic performance. JI consist of two parameters. One of them describes the relative change in pore volume per unit of relative change in reservoir pressure, and the second is the relative change in pore volume per unit of relative change in formation porosity. Here, “relative change” means a change in a parameter relative to its original value. These parameters are dimensionless and can have values around or equal to unity. A new conceptual framework for describing reservoir drive mechanisms based on JI has been formulated. According to this framework, reservoir drive mechanism is determined by comparing the computed JI values with unity rather than relying on subjective assessments of the trend of some functional dependencies. For the first time, it has become possible to express the reservoir drive performance quantitatively and determine the level of energy activity of the reservoirs with the help of JI. Additionally, a technique has been developed to evaluate the numerical values of JI for specific oil (including volatile oil) deposits based on the production data at any stage of production. The proposed methodology was tested using data from the eighth horizon of the Russkiy Khutor field in Russia. The test results not only confirmed the reliability of the obtained model but also demonstrated the adequacy of the proposed concept as a whole. Summarizing the results of other works by the authors, the adequacy of the proposed concept for both oil, gas, and gas condensate deposits has been confirmed. The research findings are expected to contribute to updating the traditional principles used for the mathematical problem statements in fluid flow in porous formations.
A Novel Connection Element Method for Multiscale Numerical Simulation of Two-Phase Flow in Fractured Reservoirs
Authors: Zhao Hui , Zhan Wentao , Chen Zhiming , Rao Xiang 
Published: July 2024

Summary
This paper presents a novel approach to the numerical simulation of fractured reservoirs, called the connection element method (CEM), which differs from traditional grid-based methods. The reservoir computational domain is discretized into a series of nodes, and a system of connection elements is constructed based on the given connection lengths and angles. The pressure diffusion term is approximated using generalized finite difference theory. Meanwhile, the transmissibility and volume of the connection elements are determined, and pressure equations are solved discretely to obtain pressure at nodes to approximate the upstream flux along connection elements. Then, we solve the transport equation to obtain oil saturation profiles with low numerical diffusion, utilizing the discontinuous Galerkin (DG) method. Moreover, the flow path tracking algorithm is introduced to quantify the flow allocation factors between wells. In all, the pressure equation can be solved at a global coarse-scale point cloud and the saturation equation is calculated at a local fine-scale connection element. In other words, CEM is of multiscale characteristics relatively. Finally, several numerical examples are implemented to demonstrate that CEM can achieve a relatively better balance between computational accuracy and efficiency compared with embedded discrete fracture modeling (EDFM). Furthermore, CEM adopts flexible meshless nodes instead of grids with strong topology, making it more practical to handle complex reservoir geometry such as fractured reservoirs.