bluuebunny/crossref_metadata_2025_split huggingface dataset:
A study comparing the effectiveness of ondansetron versus ondansetron combined with dexamethasone for preventing postoperative nausea and vomiting in laparoscopic surgeries
Authors: Pandya Rajan B. , Sathe Deepika , Joshi Ankita , Sathe Vishwas 
Published: June 2024

Abstract

Background:
Postoperative nausea and vomiting (PONV) frequently occur as a side effect of general anesthesia, which can be intensified by the introduction of gas into the peritoneal cavity to create pneumoperitoneum during laparoscopic surgeries.

Aims and Objectives:
This study examines the comparative effectiveness of ondansetron as a standalone treatment versus its combination with dexamethasone in preventing PONV during laparoscopic surgeries. The research aims to assess the efficacy and duration of anti-nausea and anti-vomiting effects provided by ondansetron alone and in combination with dexamethasone.

Materials and Methods:
The Institutional Ethics Committee (IEC) approved the trial materials and methods following thorough deliberation. Before surgery, written informed consent was obtained from all patients. Sixty patients were recruited for the study and randomly allocated into groups, denoted as Group O and Group D, each consisting of 30 patients. Group O received intravenous administration of 4 mg of ondansetron, while Group D received a combination of 4 mg of ondansetron and 4 mg of dexamethasone intravenously 30 min before extubation.

Duration of Study:
The research was conducted at MGM Medical College and Hospital, located in Navi Mumbai, Maharashtra, India, from May 2016 to May 2017.

Results:
In this study, mild and moderate nausea were more prevalent in Group O at the 4-h mark, but there was no notable difference at 24 h. Mild and moderate retching showed no significant variance at 4 h, but Group O exhibited significantly more at 24 h. Mild, moderate, and severe vomiting were inconsequential in both groups at 4 h, but Group O showed a higher incidence of mild and moderate vomiting at 24 h. Instances of severe vomiting were absent in both groups. The need for rescue antiemetics after 24 h and medication-related side effects did not show significant differences between the two groups.

Conclusion:
The incidence of PONV was reduced in the combination group (ondansetron + dexamethasone) compared to ondansetron alone. Consequently, the combination group had a lower requirement for rescue antiemetics. Thus, the effectiveness of combination therapy surpassed that of ondansetron alone.
Educating patients about health helps slow the progression of chronic kidney disease in the eastern region of India
Authors: Dasgupta Supriya , Debnath Reeti 
Published: June 2024

Abstract

Background:
Chronic kidney disease (CKD) poses a well-documented burden, necessitating patient awareness of the importance of healthy lifestyle modifications to mitigate co-morbidities and mortality risks.

Objective:
This study aimed to assess the effectiveness of education-based conservative management in mitigating disease progression among CKD patients in the eastern region of India.

Materials and Methods:
A total of 248 CKD patients receiving outpatient department and inpatient department care at the nephrology and dialysis department of Belle Vue Clinic, Kolkata, West Bengal, India, were included in the study. Comprehensive data encompassing demographic details, socioeconomic status, clinical co-morbidities, and conservative management interventions via patient education were examined. The study compared the rise in creatinine levels with adherence to five key factors: dietary restrictions, medication compliance, follow-up appointments with physicians, management of co-morbidities, and adherence to lifestyle modifications. Each strategy was graded on a scale of 0, 1, or 2 based on compliance, with 0 indicating minimal or no compliance, 1 indicating moderate compliance, and 2 indicating strong compliance.

Results:
In this study, several factors were linked to elevated creatinine levels among CKD patients, including being in the middle-age range, male gender, living predominantly in urban areas, and working in business or service occupations. Additionally, a higher prevalence of co-existing conditions such as diabetes mellitus and hypertension was noted among CKD patients, along with documented instances of polycystic kidney disease, obstructive uropathy, and renal cell carcinoma. After educating CKD patients, those who scored 8–10 on compliance exhibited a decrease in creatinine elevation (0.35 mg/dL) among 120 cases from January 2022 to June 2023. Conversely, those with scores ranging from 5 to 7 (81 cases) showed moderate creatinine elevation (1.24 mg/dL), while those with scores of 0–4 (47 cases) demonstrated higher levels of creatinine elevation (5.48 mg/dL).

Conclusion:
This study concludes that the conservative management of CKD patients educates individuals about primary prevention of the disorder and provides a comprehensive understanding of secondary and tertiary prevention strategies. This cost-effective approach significantly impacts physical, mental, social, and psychological adjustment behaviors.
Impact of a nurse-led intervention in understanding menstrual health management among adolescent girls attending specific schools in Navi Mumbai, India
Authors: Naik Priya , Revankar Smeeta , Jadhav Vaishali Santosh 
Published: June 2024

Abstract

Background:
Premenstrual symptoms are prevalent among menstruating individuals, affecting around 75% of those who report some level of discomfort during their cycles. However, approximately 10% of women endure premenstrual syndrome (PMS), marked by symptoms that significantly disrupt daily functioning. PMS remains poorly comprehended and difficult to diagnose. The aim of this study was to assess the efficacy of an intervention and analyze the disparity in knowledge levels between the two groups.

Materials and Methods:
A genuine experimental design was employed using a pretest and post-test control group approach. A simple random sampling lottery method was used to select 40 adolescent girls for the study and control groups. These girls, aged 12–15 years, were chosen from specific schools in Navi Mumbai, adhering to predetermined inclusion criteria. A structured knowledge questionnaire was administered to both groups. At 1 week post-test, the study group received a nurse-led intervention through a planned teaching program. Data analysis included descriptive and inferential statistics.

Results:
In the control group, pretest knowledge scores averaged around 57.5%, suggesting a moderate level of knowledge. Conversely, the study group exhibited an average pretest knowledge score of 60%. Examining post-test knowledge scores, it is evident that in the control group, the majority (42.5%) demonstrated average knowledge, while in the study group, 67.5% exhibited excellent knowledge. Paired t test findings indicated a significant influence of the planned teaching program in the study group compared with the control group, with a P value of 0.001 at a significance level.

Conclusion:
Adolescent girls in the selected schools lacked knowledge about menstrual health management. Consequently, the nurse-led intervention on menstrual health management significantly improved knowledge among the control group of adolescent girls.
Paracetamol-induced hepatotoxicity in a malnourished patient: A case report
Authors: Shukla Sudhanshu , Sridhar Tejashree , Hiremath Jayasheela Siddalingayya , Nyamagoud Sanathkumar B. , Swamy Viswanatha Agadi Hiremath 
Published: June 2024

Abstract
Acetaminophen, an analgesic and antipyretic with a favorable safety profile, is used globally. However, excessive doses can lead to severe hepatotoxicity and acute liver failure. We present a case report that describes the unfortunate demise of a 48-year-old male patient with colon carcinoma who developed severe hepatotoxicity attributed to the administration of paracetamol following right radical hemicolectomy. Despite the patient receiving paracetamol at a dosage below the recommended limit under medical supervision, he experienced a rapid deterioration in liver function, leading to a cascade of life-threatening complications. The intricate interplay between medication administration and patient-specific factors emphasizes the ongoing need for the medical community to evolve and optimize treatment strategies for improved patient outcomes.
Prospects of emerging 3D bioprinting technologies: major technology components, technology developers, and end users—Part I
Authors: Ghosh Prasanta K. 
Published: June 2024

Abstract
Bioprinting technology aims to create 3D structures with living cells to mimic real tissue and organ functions. The process involves various additive technologies, including 3D bioprinters and bioinks. Bioinks comprise hydrogels, scaffolds, additives, growth factors, and living cells. While much of the technology is still in the exploratory stages, it has successfully produced living tissue, blood vessels, and bones. Research suggests the potential for bioprinting whole organs to revolutionize medical procedures. Current major business components include various types of bioprinters and advanced bioinks. Advancements in technologies such as cellular reprogramming hold the potential to enhance the development of superior bioinks, thereby enabling the fabrication of 3D bioprinted tissues. 3D bioprinting technology offers significant benefits across research, personalized medicine, and other applications. This review provides a flavor of the potential benefits of using 3D bioprinting technology in various areas of usage, including Research and Development (R&D), and its applications on a wide spectrum, including personalized medicine.
Health status, menstrual hygiene practices, and anthropometric correlations among minority school girls
Authors: Gayathri Batchu Naga , Lavanya C. , Bolla Chandrasekhar Reddy 
Published: July 2024

Abstract

Background:
Age group of 10–19 years has been designated as the adolescence period. This period decides future health and nutritional status. Girls are future mothers. Adolescents constitute 25% of the global population. Most of these populations are from developing countries.

Objective:
To study health status, menstrual hygiene practices, and anthropometric correlations among minority school girls.

Methods:
An institution-based cross-sectional study was carried out among 112 girls of age 11–18 years from a minority school. Socio-demographic information, complete general, and systemic examination as well as questions related to personal hygiene practices and menstrual hygiene practices were taken. Height, weight, and blood pressure were recorded as per the standard protocol. Body mass index (BMI) was calculated.

Results:
The prevalence of undernutrition was very high, i.e. 57.1%. The prevalence of refractive errors was 20.5%. Regarding personal hygiene practices, most of the girls were seen to follow good practices. Hand hygiene was present in 97.3% for washing hands before eating and among 98.2% for washing hands with soap and water after defecation. Regarding menstrual hygiene practices, only one girl told that she used the old cloth during menstruation and two girls disposed the pads improperly. Significant correlation was seen between age and BMI; systolic blood pressure (SBP) and BMI; diastolic blood pressure and BMI; and duration of stay in the hostel and SBP. Age was correlated with the height and BMI. When we compared mean height, weight, and BMI across age categories, we found that mean height was significantly more in higher age. Mean BMI was significantly lesser in higher age group. However, mean weight was almost similar.

Conclusion:
The prevalence of malnutrition was high. As the age increased, BMI decreased indicating that the given nutrition is not sufficient for their growing age. Hence, there is a need to give additional food supplementation for proper growth and nutrition. Awareness on personal and menstrual hygiene was very good.
The clinical efficacy, outcomes and quality of life of diabetic disease patients treated with dapagliflozin
Authors: Talla Venu , Kumar P. Naveen , Vemula Manusha , Bommu Shivani , Natukula Keerthi , Tangeda Saritha Jyostna 
Published: June 2024

Introduction:
Diabetic kidney disease (DKD) is a leading cause of end-stage renal disease and a common serious complication that affects 1/3rd of type-1 and half of type-2 diabetes mellitus patients. In the early stages of DKD-RAAS blockades (angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers) and antihyperglycemic agents such as sodium-glucose transport protein (SGLT) 2 inhibitors, glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors may help prevent DKD by lowering blood glucose levels and through intrinsic renal protection. SGLT2 inhibitors are a new class of oral antidiabetic drugs, which delay the progression of DKD. Dapagliflozin is a drug of choice when the estimated glomerular filtration rate (eGFR) is 25–75 mL/min/1.73 m2 and urine albumin–creatinine ratio ≥≥30 mg/mmol.

Aim and Objectives:
The aim of the study was to evaluate the clinical outcomes of dapagliflozin in DKD and to check the complications and quality of life of the patients after treatment.

Methodology:
It was a prospective observational study conducted for a period of 6 months in a tertiary care hospital. The data were collected from the 49 patients with DKD who underwent treatment with dapagliflozin, after approval of the protocol by the IEC. The statistical analysis was done using SPSS software, V.22.(1) 1. SPSS I. IBM SPSS Statistics Version 22 Statistical Software: Core System Users’ Guide. SPSS Inc. 2014.

Results and Discussion:
The majority of patients enrolled were males (81.63%) compared to females (18.36%) and most of them were geriatrics > 60 years. The majority of patients received dapagliflozin 10 mg, followed by few patients with 5 mg. The effectiveness of dapagliflozin was observed by statistically significant improvement in serum creatinine (P < 0.05), BUN (P < 0.05), and blood urea (P ≤ 0.05). Clinically significant improvement was observed in eGFR, creatinine clearance, serum sodium, potassium, chlorides, glycated hemoglobin levels, and body mass index (P > 0.05), which was statistically insignificant. Statistically significant improvement in the quality of life (P < 0.001) of patients was observed. Out of 49, two patients reported with UTI which may be a suspected drug-related side effect.

Conclusion:
The study concludes that dapagliflozin has a positive impact on treating DKD. The overall quality of life of the patients was moderately improved. These outcomes suggest that dapagliflozin may become the main line therapy in patients suffering from DKD.
Eye perforation during retrobulbar anesthesia
Authors: Sobrinho Marcelo Vicente de Andrade , Fonseca Andre Luis , Jacobucci Vitor Guilhermino , Ferrer Ivana 
Published: June 2024

Abstract
Case report of an 81-year-old patient who suffered an eye perforation during retrobulbar anesthesia before her cataract surgery. The patient presented with eye hypotony and had her surgery canceled. After the complementary examination and image exams, the hypothesis of globe perforation with retinal detachment was confirmed, and the patient underwent a posterior vitrectomy. The objective of this case report is to present the characteristic findings and management of this rare but well-known complication.
Literasi Digital Informasi Kebencanaan selama Erupsi Gunung Semeru pada Perempuan Terdampak di Kabupaten Lumajang Jawa Timur
Authors: Ida Rachmah , Wahyudi Irfan , Kinasih Sri Endah , Rozi Romdhi Fatkhur 
Published: June 2024

This research focuses on the importance of disaster information literacy for women's groups. This is crucial as a factor that determines the level of safety of residents in potentially disaster-affected areas, particularly those who had been affected by the eruption of Mount Semeru in 2023 in Lumajang, East Jawa. Through gendered methodology and open ended questions, researchers managed to map the main problems faced by women's groups in accessing important information sources to reduce disaster risk. Conducted between May and June 2023, the research underscored a significant gap in women's literacy concerning digital media, such as social platforms and mobile applications. Even though women are a group that has broad access to social life and can be a liaison of information from outside to all family members. The findings in this study also emphasize the importance of utilizing social capital and integrating women's groups with the government and the main sources of disaster information. By establishing an effective system for distributing disaster knowledge, there is a potential to enhance the disaster information literacy of women's groups and bolster the safety of residents in disaster-prone areas through the implementation of risk communication protocols.Abstrak Penelitian ini berfokus pada pentingnya literasi informasi bencana bagi kelompok perempuan. Hal ini sangat penting karena merupakan faktor penentu tingkat keselamatan penduduk di daerah yang berpotensi terkena dampak bencana, terutama mereka yang terdampak oleh letusan Gunung Semeru pada tahun 2023 di Lumajang, Jawa Timur. Melalui metodologi berbasis gender dan pertanyaan terbuka, para peneliti berhasil memetakan masalah utama yang dihadapi oleh kelompok perempuan dalam mengakses sumber informasi penting untuk mengurangi risiko bencana. Dilaksanakan antara bulan Mei dan Juni 2023, penelitian ini menyoroti kesenjangan yang signifikan dalam literasi perempuan mengenai media digital, seperti platform sosial dan aplikasi seluler. Meskipun perempuan adalah kelompok yang memiliki akses yang luas ke kehidupan sosial dan dapat menjadi perantara informasi dari luar kepada semua anggota keluarga. Temuan dalam penelitian ini juga menekankan pentingnya memanfaatkan modal sosial dan mengintegrasikan kelompok perempuan dengan pemerintah dan sumber utama informasi bencana. Pembentukan aliran distribusi pengetahuan bencana yang baik berpotensi meningkatkan kemampuan literasi informasi bencana kelompok perempuan dan meningkatkan keselamatan penduduk di daerah yang berisiko terdampak bencana melalui protokol komunikasi risiko.
Influence Of Project Based Learning Model To Students' Problem-Solving Abilities On The Material Of Cubes And Blocks
Authors: Rahayu Ningsih Sri Lestari , Agustinsa Ringki , Rahimah Dewi 
Published: June 2024

This study aimed problem-solving abilities on cube and block lesson for eighth grade in SMP Negeri 8 Bengkulu City. This study was quasi-experimental research with The Nonequivalent Posttest Only Control Group Design. The population of this study was all eighth-grade students of SMP Negeri 8 Bengkulu City in academic year of 2022/2023. The samples of this study were students of class VIII-3 as the experimental class that used the Project Based Learning model and students of class VIII-4 as the control class that used a conventional learning method who were selected through purposive sampling. The instrument used in this study was a problem-solving ability test sheet. The results of hypothesis testing showed that the value > which was 2.751> 1.671. The results of this study indicated that there was an influence of the application of the Project Based Learning model on students' mathematical problem-solving abilities on cube and block lesson for eighth grade in SMP Negeri 8 Bengkulu City.
The Effectiveness of The Stad-Type Cooperative Learning Model on The Mathematical Problem-Solving Ability of Elementary School Students
Authors: Yuliana Luthfi Fajra , Murtiyasa Budi 
Published: June 2024

Students’ ability to solve problems is still lacking because they often rely on memorizing concepts. The purpose of this research is to determine the effectiveness of the STAD-type cooperative learning model in helping students solve mathematical problems. This type of research used descriptive quantitative research. This research approach used an experiment with a Quasi experimental design in the form of a pre-test post-test control group design. This research was conducted using a sample of fifth-grade students at Dukuhan Kerten State Elementary School, even semester of the 2022/2023 academic year. This research used a cluster random sampling technique where two experimental and control classes were obtained. Independent Sample T-Test is one type of data analysis test used. STAD and conventional learning models show different levels of effectiveness, as seen from the Sig. (2-tailed) of 0.044 < 0.05 indicated that is rejected. In the Independent sample t-test the mean value of the experimental class also bigger than the mean of the control class, which is 0.4280 > 0.2708. It showed that in improving fifth-grade students’class V mathematics problem solving skills on geometric material, the STAD learning model is more effective to use.
MODEL KEPEMIMPINAN GEREJA YANG KONTEKSTUAL BERDASARKAN STRUKTUR BUDAYA BATAK MENGGUNAKAN MODEL ANTROPOLOGIS STEPHEN B. BEVANS
Authors: Sinaga Andri Vincent , Panjaitan Mangaratua , Hutasoit Marangkup 
Published: June 2024

Penelitian ini berfokus pada perumusan model kepemimpinan gereja yang kontekstual berdasarkan struktur budaya Batak. Masalah utama yang dikaji adalah kepemimpinan gereja Batak saat ini masih didominasi oleh gaya kepemimpinan Barat dan juga model kepemimpinan gereja yang seringkali dianggap kurang responsif (adaptif atau kontekstual) terhadap budaya dan nilai-nilai sosial-budaya setempat sehingga belum sepenuhnya kontekstual dan relevan dengan nilai-nilai budaya Batak. Penelitian ini menggunakan pendekatan model antropologis Stephen B. Bevans untuk memahami budaya Batak secara mendalam dan merumuskan model kepemimpinan gereja yang kontekstual. Tujuan penelitian ini adalah untuk merumuskan model kepemimpinan gereja Batak yang kontekstual dan relevan dengan struktur budaya Batak. Metode penelitian yang digunakan adalah kualitatif, dengan pendekatan studi kepustakaan. Hasil penelitian menunjukkan bahwa integrasi nilai-nilai budaya Batak seperti sahala (wibawa), Dalihan Na Tolu (DNT), Habonaron Do Bona (HdB), dan falsafah marga perlu dijadikan basis bagi model kepemimpinan gereja Batak yang kontekstual. Model kepemimpinan gereja Batak sebaiknya mengedepankan sifat pengayom, pelayanan, menghargai, dan kebersamaan (solidaritas) sesuai dengan nilai-nilai budaya tersebut. Integrasi nilai-nilai budaya Batak penting dilakukan untuk membentuk kepemimpinan gereja Batak yang tetap berakar pada budaya lokal namun setia pada warisan iman Kristen.
Kajian Model Aplikasi Pupuk Organik Cair Pengaruhnya Terhadap Pertumbuhan dan Hasil Tanaman Terong (Solanum melongena L.)
Authors: Haryanta Dwi , Sa’adah Tatuk Tojibatus , Thohiron Moch. 
Published: July 2024

Kajian tentang pengaruh bahan baku dan konsentrasi pupuk organik cair (POC) terhadap pertumbuhan dan hasil tanaman sudah banyak diteliti. Penelitian bertujuan untuk mencari teknik aplikasi pupuk organik cair yang efektif berpengaruh terhadap pertumbuhan dan hasil tanaman terong. Percobaan faktorial dengan perlakuan faktor satu adalah bahan baku pembuatan Pupuk Organik Cair (POC) yang terdiri dari 8 level yaitu P1 = diberi POC dari campuran 6 bahan baku, P2 = diberi POC dari limbah sayuran, P3 = diberi POC dari limbah buah, P4 = diberi POC dari limbah kecambah, P5 = diberi POC dari limbah makanan (catering), P6 = diberi POC dari limbah ikan lele (jerohan), dan P7 = diberi POC dari limbah potong hewan (darah). Perlakuan Faktor dua adalah cara pemberian POC yang terdiri dari disemprot (B1), disiram atau dikocor (B2), dan disemprot dan disiram (B3). Pemberian POC dengan cara disiram atau dikocor berpengaruh paling bagus terhadap hasil tanaman terong ditunjukkan pada variabel jumlah buah 13,95 buah per tanaman dan berat buah 1.621,32 g per tanaman berbeda nyata dengan pemberian dengan cara disemprot jumlah buahnya 8,64 buah per tanaman dan berat buah 982,09 g pert tanaman. Pengembangan tanaman sayuran dalam sistem urban farming direkomendasikan memakai POC dari limbah makanan catering yang selama ini tersedia banyak di masyarakat dan aplikasinya dengan cara disiram atau dikocor.