bluuebunny/crossref_metadata_2025_split huggingface dataset:
MANAJEMEN KEPALA SEKOLAH DALAM MENINGKATKAN MOTIVASI KINERJA GURU DI SMA NEGERI 1 CIBATU KABUPATEN PURWAKARTA
Authors: Yuniawati Yuniawati , Erawan Raden Dewangga Tresna , Habibie M. Faiz , Yoseptry Ricky 
Published: July 2024

The principal's management ability is the most important factor in order to improve the quality and progress of the school. With the management, it is hoped that the principal can increase the motivation of teacher performance. Motivation of teacher performance certainly requires a strong role of the principal in planning, organizing, directing and controlling. The purpose of this study is to describe and analyze the principal's management regarding planning, organizing, directing and control. The purpose of this study is to describe and analyze the principal's management regarding planning, organizing, directing and controlling so as to increase the motivation of teacher performance in schools. This research uses a qualitative approach with a case study method. The source of this research data is primary data and secondary data. Data collection techniques through observation, interviews, and documentation. Analysis of research data is carried out through by Steps: (1) Collecting data, (2) Reducing data, (3) Exposure of data, and (4) drawing conclusions. The results of the study are: 1) The ability of the principal's management in planning teacher performance motivation at SMA Negeri 1 Cibatu; 2) The principal's management ability in organizing teacher performance motivation at SMA Negeri 1 Cibatu according to procedures; 3) The principal's management ability in directing teacher performance motivation at SMA Negeri 1 Cibatu has been running well; and 4) The ability of the principal's management in controlling or supervising to increase teacher performance motivation at SMA Negeri 1 Cibatu by monitoring and evaluating. From the overall management of the principal, it can be stated that the Principal of SMA Negeri 1 Cibatu Purwakarta Regency has been able to increase the motivation of teacher performance.
ANALISIS PRIORITAS PEMELIHARAAN JALAN KOTA KOTAMOBAGU MENGGUNAKAN METODE ANALYTICAL HIERARCHY PROCESS (AHP)
Authors: Mananoma Tiny , Fithra Mokoagow Abdul , Mokoginta Gita Virginita , Damopolii Virgina Dian Bayanasari 
Published: July 2024

Roads infrastructure has a very important role in supporting economic, social and cultural activities of a region. Road maintenance is an activity related to road maintenance and repairs that are necessary and planned to maintain road conditions so it can be function optimally to serve traffic during the lifespan of the road. Kotamobagu Government has limitations in road maintenance, including the budget provided by the APBD is very limited, and policy makers in determining maintenance have not been based on objective assessments and the assessment of determining road maintenance priorities is still based on subjective assessments and have not based on accountable standards yet. Therefore, it is necessary to have a strategy for determining road priorities based on objective assessments and precise criteria. The research use Analytical Hierarchy Process (AHP) method as a determinant of the priority order for road maintenance in Kotamobagu. The criteria that being used are road conditions, annual average daily traffic (LHR) and handling costs. Collecting data was taken through direct submission to the Departmen of Public Works and Urban Planning, interviews and filling out questionnaires to relevant stakeholders.
PENGARUH AROMATERAPI TERHADAP PENURUNAN NYERI PADA PASIEN DENGAN KANKER KOLOREKTAL : A SCOPING REVIEW
Authors: Nia Rosliany  , Wahdini Rizqa , Ribka Sabarina Panjaitan  
Published: July 2024

Pain is a prevalent symptom among cancer patients, accompanied by fatigue, sleep disturbances, anxiety, and depression. Aromatherapy, a non-pharmacological method, can safely reduce pain without negative side effects. It involves the use of essential oils as therapeutic agents, absorbed through the skin or olfactory system. This study aims to evaluate the impact of aromatherapy on pain reduction in colorectal cancer patients. This study uses a scoping review methodology based on PRISMA guidelines. The review encompasses three databases: PubMed, Sage, and ScienceDirect, covering the period from 2019 to 2024. Specific search terms were utilized based on inclusion criteria for article selection. Out of 2403 research articles, six were chosen after screening abstracts and full texts to identify studies meeting the inclusion criteria. The analysis identified various types of aroma therapy used for pain reduction. The studies reviewed indicated that aromatherapy was administered through massage and inhalation using essential oils like lavender, lemon, peppermint, geranium, and others. Aromatherapy showed significant positive effects in reducing pain compared to placebo or usual care control groups, as measured by the visual analog scale (VAS). The study's findings suggest that aromatherapy effectively reduces stress, depression, and pain perception in patients with colorectal cancer.

Keywords: Aroma therapy; Colorectal Cancer; Pain
AS PRINCIPAIS FORMAS DE VIOLÊNCIA SOFRIDAS PELAS PESSOAS IDOSAS NO PARANÁ NOS ANOS DE 2021 E 2022 E AS INTERVENÇÕES QUE A POLÌCIA MILITAR PODE REALIZAR ASSEGURANDO OS DIRETOS CONSTITUICIONAIS DESTES INDIVÍDUOS
Authors: De Oliveira Durães Giovani 
Published: July 2024

A violência contra a pessoa idosa vem aumentando muito nos últimos tempos e o modo como a sociedade trata esta parcela da população representa o grau de civilidade de seus integrantes. Diante deste fato, surgiu a problemática para esta pesquisa, como identificar as violências sofridas pelas pessoas idosas no estado do Paraná e como acontece a atuação da polícia militar na defesa desta população tão vulnerável? Buscando respostas a este questionamento, o objetivo central foi de verificar como os policiais militares podem atuar na defesa das pessoas idosas frente às violências praticadas contra esta parcela da população, algo que cresce a cada dia no estado do Paraná. A metodologia empregada foi uma pesquisa de campo, na Secretaria de Justiça, Família e Trabalho do Estado do Paraná - SEJUF, no Disque Idoso Paraná, que tem sua sede na cidade de Curitiba, capital do estado. E os achados demonstraram que no ano de 2021 a violência patrimonial e financeira foi a mais denunciada, totalizando 34,6% dos casos, sendo as agressões verbais e psicológicas 25,1%, negligências 20,9%, agressões físicas 12,9% e abandono 6,5%. Já no ano de 2022, a predominância das denúncias foi de violência verbal e psicológica com um total de 33,6%, negligência 26,1%, violência patrimonial e financeira 21,2%, agressões físicas 11,2% e abandono 7,9%. Assim, foi possível constatar que os indicadores de violência variaram nos dois anos, mas que se encontram em níveis bem altos e vêm de encontro a muitas outras pesquisas realizadas.
Hubungan Dukungan Keluarga dengan Kepatuhan Minum Obat pada Pasien TB Paru di Puskesmas Sei Suka
Authors: Togatorop Linawati , Suharnida Yuni , Hanafiah Yusuf , Saragih Sontina 
Published: July 2024

Background: Tuberculosis is an infectious disease that can attack all levels of society. The main step in treating pulmonary TB is to obediently take medication. Anti-pulmonary TB medication requires quite a long time so there needs to be support from the family to support patient compliance in undergoing the treatment process. Method: This type of research is correlation analysis with a cross sectional research design. This research was conducted at the Sei Suka Health Center in September - October 2023. The population in this study were all pulmonary tuberculosis patients at the Sei Suka Health Center, Batu Bara Regency, North Sumatra. The sampling technique in this research was total sampling so that a sample of 53 people was obtained. Analysis using the chi-square test. Results: Compliance with taking medication for pulmonary TB patients has a significant relationship with instrumental support, information support, appreciation and emotional support with a significant value of p=0.010 so p<0.05. Conclusion: that there is a relationship between instrumental support, information support, appreciation and emotional support with medication adherence in pulmonary TB patients in the Sei Suka Community Health Center Working Area.
Fenofibrate and diabetic retinopathy
Authors: Karti Omer , Osman Saatci Ali 
Published: July 2024

Background: Diabetic retinopathy (DR), a sight-threatening ocular complication of diabetes mellitus, is one of the main causes of blindness in the working-age population. Dyslipidemia is a potential risk factor for the development or worsening of DR, with conflicting evidence in epidemiological studies. Fenofibrate, an antihyperlipidemic agent, has lipid-modifying and pleiotropic (non-lipid) effects that may lessen the incidence of microvascular events.

Methods: Relevant studies were identified through a PubMed/MEDLINE search spanning the last 20 years, using the broad term “diabetic retinopathy” and specific terms “fenofibrate” and “dyslipidemia”. References cited in these studies were further examined to compile this mini-review. These pivotal investigations underwent meticulous scrutiny and synthesis, focusing on methodological approaches and clinical outcomes. Furthermore, we provided the main findings of the seminal studies in a table to enhance comprehension and comparison.

Results: Growing evidence indicates that fenofibrate treatment slows DR advancement owing to its possible protective effects on the blood-retinal barrier. The protective attributes of fenofibrate against DR progression and development can be broadly classified into two categories: lipid-modifying effects and non-lipid-related (pleiotropic) effects. The lipid-modifying effect is mediated through peroxisome proliferator-activated receptor-alpha activation, while the pleiotropic effects involve the reduction in serum levels of C-reactive protein, fibrinogen, and pro-inflammatory markers, and improvement in flow-mediated dilatation. In patients with DR, the lipid-modifying effects of fenofibrate primarily involve a reduction in lipoprotein-associated phospholipase A2 levels and the upregulation of apolipoprotein A1 levels. These changes contribute to the anti-inflammatory and anti-angiogenic effects of fenofibrate. Fenofibrate elicits a diverse array of pleiotropic effects, including anti-apoptotic, antioxidant, anti-inflammatory, and anti-angiogenic properties, along with the indirect consequences of these effects. Two randomized controlled trials—the Fenofibrate Intervention and Event Lowering in Diabetes and Action to Control Cardiovascular Risk in Diabetes studies—noted that fenofibrate treatment protected against DR progression, independent of serum lipid levels.

Conclusions: Fenofibrate, an oral antihyperlipidemic agent that is effective in decreasing DR progression, may reduce the number of patients who develop vision-threatening complications and require invasive treatment. Despite its proven protection against DR progression, fenofibrate treatment has not yet gained wide clinical acceptance in DR management. Ongoing and future clinical trials may clarify the role of fenofibrate treatment in DR management.
Surgical management of chronic sixth cranial nerve palsy: case report and literature review
Authors: Hakimeh Christine , Shahraki Kourosh , Courtois Luc , W. Suh Donny 
Published: July 2024

Background: Esotropia resulting from sixth cranial nerve palsy can substantially impact an individual’s visual acuity and overall quality of life. If the condition does not resolve in 6–10 months, surgical intervention may be necessary. Various muscle surgeries may be considered, with vertical rectus muscle transposition emerging as the primary option for treatment of complete palsy. However, this technique carries the risk of anterior segment ischemia and post-surgery deviations. Herein, we present a successful treatment of chronic complete sixth nerve palsy using a modified Nishida procedure, without splitting or tenotomy, and an adjunct botulinum toxin A (BTA) injection in the ipsilateral medial rectus muscle.

Case Presentation: A 59-year-old woman with a history of traumatic sixth nerve palsy had previously undergone horizontal muscle strabismus surgeries. Following multiple left medial rectus recessions, lateral rectus resection, and BTA injections, esotropia persisted. The worsening of her condition led to emotional distress and impaired social interaction. Initial examination revealed marked esotropia and limited left eye abduction. Magnetic resonance imaging (SIGNA MR750w, GE Healthcare, Waukesha, WI, USA) of the left eye revealed a contracted medial rectus muscle and substantial atrophy of the left lateral rectus muscle. A modified Nishida procedure was performed with an injection of 3 units of BTA into the ipsilateral medial rectus muscle, resulting in improved ocular alignment and stable findings after nine postoperative months. Furthermore, we supported our successful outcome with a summary of similar reported cases of sixth nerve palsy managed using the modified Nishida procedure with or without adjunctive procedures.

Conclusions: Following the modified Nishida procedure, the patient experienced a reduction in diplopia, improved ocular alignment and stability, and an increased binocular diplopia-free field. This case underscores the importance of an individualized approach to complex strabismus cases and highlights the modified Nishida procedure as a valuable tool in such circumstances. In the future, strabismus management will focus on refining personalized treatment and exploring innovative techniques for complex cases. Our success in using a combination of Nishida procedure and BTA injection should be further investigated in large-scale studies.
Transforming Toxic Debates towards European Futures
Authors: Üzelgün Mehmet Ali , Giannouli Iliana , Archontaki Ioanna , Odstrčilová Klára , Thomass Barbara , Álvares Cláudia 
Published: July 2024

Online toxicity refers to a spectrum of problematic communicative phenomena that unfold in various ways on social media platforms. Most of the current efforts to contain it focus on computational techniques to detect online toxicity and build a regulatory architecture. In this paper, we highlight the importance of focusing on the social phenomena of toxicity, and particularly, exploring the public understanding and future imaginaries of toxic debates. To explore how users construe online toxicity and envisage the future of online discussions, we examine 41 scenarios produced by European experts from the field of technology and culture. Through a content analysis informed by a narrative approach and insights from futures studies, we identify three myths that characterize the future scenarios: technological disruption, societal fragmentation, and digital Enlightenment. After a discussion of their relations, we conclude by stressing the importance of platform transparency and user empowerment.
Unresolved issues of using ultrasound elastography methods in patients with mononeuropathy of the lower limb girdle and free part of the lower limb
Authors: Yurkovskiy А. М. , Pismennikova E. I. 
Published: July 2024

Objective. Systematization of data and analysis of the diagnostic effectiveness of ultrasound elastography for mononeuropathies of the lower limb girdle and free part of the lower limb.Materials and methods. Publications in the PubMed, EMBASE and Web of Science systems were analysed thoroughly, describing cases of the use of imaging methods in patients with mononeuropathy of the lower limb girdle and free part of the lower limb.Results. The most promising for implementation in wide clinical practice ultrasound elastography techniques have been identified. The use of them can, if refined, provide early diagnosis of mononeuropathies of the lower limb girdle and the free part of the lower limb.Conclusion. The use of ultrasound elastography for the diagnosis of mononeuropathy of the lower limb girdle and free part of the lower limb is hampered by the lack of clear ideas regarding the reference values of stiffness indices (kPa, m/s) for specific peripheral nerves and the possible influence of artifacts from bones and other adjacent tissues on these stiffness indices. In addition, there is no clear algorithm for choosing an ultrasound elastography technique, depending on the location and cross-section of the nerve. Solving these issues will allow optimizing the use of ultrasound elastography for the diagnosis of mononeuropathies of the lower limb girdle and the free part of the lower limb.
The role of vaginal ectopia of the external urethral orifice in the development of morphologic changes bladder of the mucosa in women
Authors: Lemtygov M. B. 
Published: July 2024

Objective. To evaluate morphological changes in the bladder mucosa against the background of vaginal ectopia of the external urethral orifice and/or urethral hypermobility in women, efficacy and safety of transposition of the external urethral orifice as a method of surgical treatment of postcoital cystitis.Materials and methods. The study group included 29 patients undergoing surgical treatment for chronic recurrent postcoital cystitis in the form of transposition of the external orifice of the urethra according to B.K. Komiakov. Before surgical treatment, all studied patients underwent cystoscopy with bladder biopsy. The obtained biopsy specimens were fixed in buffered formalin, further processed in increasing concentrations of alcohols, and embedded in paraffin blocks according to the standard technique. Sections were obtained from the blocks and mounted on histologic slides and stained with hematoxylin and eosin. The follow-up time was 12 months after surgical treatment.Results. Histologic confirmation of squamous cell metaplasia was revealed in 2/29 (6.8%) patients in the bladder fundus projection and in 23/29 (79.3%) in the Lieto triangle projection, lymphoid infiltration was determined in 14/29 (48.2%) patients in the fundus projection and in 21/29 (72.4%) in the Lieto triangle projection. The combined squamous cell metaplasia and lymphoid infiltration was detected in 16/29 (55,2%) patients in the Lieto triangle projection and in 1 (3,4%) patient in the bladder fundus projection. At follow-up examination, 28 patients had no recurrence of postcoital cystitis. Inflammatory changes of the bladder mucosa underwent regression in 20 patients in control cystoscopy. Morphologically, lymphoid infiltration was detected in 1/29 (3.4%) patients, and squamous cell metaplasia was determined in 5/29 (17.2%) patients.Conclusion. As a result of long-term inflammatory process in the bladder in the course of frequent recurrences of postcoital cystitis, the bladder wall undergoes morphologic changes that require mandatory morphologic verification. By surgical release of pathogenetic factor - vaginal ectopia of the external urethral orifice and/or urethral hypermobility, it is possible to achieve regression of morphologic changes in the bladder mucosa.
Influence of pooling mesenchymal stem cells on the suppression of proliferative activity of T-lymphocytes
Authors: Rynda A. H. , Hancharou A. Y. , Antonevich N. G. 
Published: July 2024

Objective. To determine the effect of pooling (merging) of single cultures of olfactory mucosa-derived mesenchymal stem cells (MSCs) of the nasal cavity on the suppression of the proliferative activity of T-lymphocytes.Materials and methods. Using flow cytometry, the effect of pooling single cultures of MSCs obtained from healthy donors (n=7) on the mitogen-induced proliferation of T-lymphocytes in the peripheral blood of volunteers (n=5) was studied. The proliferation index and the number of dividing CD3+ T-cells were assessed by changes in the fluorescence intensity of Tag-it Vio. Statistical processing of the obtained data was carried out using non-parametric statistics.Results. An evaluation of 35 variants of co-culture of single MSCs with T-cells and 33 variants of co-culture of pooled MSCs with T-cells was performed. The inhibitory effect of both single (p = 0.0001) and pooled MSCs (p = 0.0001) onPHA-induced proliferation of CD3+ T-cells in the total fraction of peripheral blood lymphocytes was identified. It was shown that pooled MSCs have a significantly more pronounced suppressive effect on T-cell proliferation compared to single MSCs (p=0.000004).Conclusion. PoolMSCs have a significantly more pronounced effect in suppressing PHA-induced proliferation of peripheral blood T-cells compared to MSC monocultures, which justifies the use of poolMSCs in medicine to achieve better results in the treatment of immune-mediated diseases.
Maintaining and strengthening the reproductive health of women living with HIV: legislative support in the Republic of Belarus
Authors: Teslova O. A. , Zhavoronok S. V. , Skripko O. A. 
Published: July 2024

Objective. To review and systematize the legislative acts of the Republic of Belarus on the organization and provision of medical care and services to maintain and strengthen reproductive health for women living with HIV, and to determine the need for their updating.Materials and methods. The article discusses the legal documents of the health care system regulating the organization and provision of medical care to women living with HIV, and the practice of their use in screening women for HIV, pregnancy and childbirth care, including drug provision and antiretroviral therapy, termination of pregnancy, family planning, providing gynecological care to women and providing services for the prevention of HIV infection in teenage girls, monitoring cases of HIV infection on the territory of the Republic of Belarus.Results. In the context of the reproductive needs of women living with HIV, the current regulatory documents establish many norms and recommendations that have lost their relevance and validity. There are no modern recommendations for the organization and provision of gynecological care that take into account the particularities of genital tract diseases in HIV-infected women of different ages. The multiplicity of recommendations from various clinical protocols creates uncertainty when making decisions by medical workers, or becomes a precedent for examining the quality of medical care.Conclusion. The development of a comprehensive clinical protocol based on scientifically based data on the modern characteristics and reproductive needs of women living with HIV, as well as timely revision of legislative acts on the provision of medical care to people living with HIV, with additions and changes, will make it possible to provide targeted medical care and maintain their reproductive health.