bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of whole-body vibration on body composition, microbiota, cardiometabolic markers, physical fitness, and quality of life after bariatric surgery: protocol for a randomized controlled trial
Authors: Gómez-Bruton Alejandro , Irún Pilar , Matute-Llorente Angel , Lozano-Berges Gabriel , Moradell Ana , Ara-Gimeno Susana , Subias-Perie Jorge , Sánchez-Luengo Marta , Hijos-Mallada Gonzalo , García-Mateo Sandra , Arechavaleta Samantha , Palacios Fanlo María José , Lanas Angel , Casajús Jose A. 
Published: June 2024

Abstract
Background
Morbid obesity is a complex chronic condition characterized by a body mass index of 40 kg/m2 or higher. The incidence of the condition is on the rise in developed countries, and bariatric surgery has been proposed as a potential solution to address this trend. Nonetheless, bariatric surgery may also result in adverse effects, including a reduction in bone mineral density (BMD) and muscle mass, as well as an increased risk of fractures. The present study aims to elucidate the effects of bariatric surgery and whole-body vibration (WBV) training on body composition, microbiota, physical fitness, quality of life, and cardiometabolic markers.

Methods
Twenty-eight participants (14 females), aged 18 to 50 years, will undergo sleeve gastrectomy surgery. They will be randomly allocated into a control group or a WBV training group. The WBV group will train three times per week with increasing intensities and duration ranging from 30 to 45 min over the 4-month training period. Measurements of body composition (dual-energy X-ray absorptiometry and peripheral quantitative computed tomography), physical fitness (muscular strength, agility, cardiorespiratory fitness, and balance), gait biomechanics, cardiometabolic markers, gut microbiota, quality of life, and physical activity levels will be collected at four different time points: (1) prior to the surgery, (2) 45 days post-surgery, (3) 6 months post-surgery, and (4) 18 months post-surgery.

Discussion
Both groups are expected to experience improvements in most of the aforementioned variables. Nonetheless, we expect the WBV group to show larger improvements proving that the training is effective and safe.

Trial registration
Clinicaltrials.gov NCT05695599. Registered on January 25, 2023.
Effectiveness of a positive psychology and mindfulness-based app on mental health for parents of children with a neurodevelopmental disorder: study protocol of a pragmatic international randomized controlled trial
Authors: Tönis Kim J. M. , Drossaert Constance H. C. , ten Klooster Peter M. , Schaer Marie , Bourgeron Thomas , Buitelaar Jan K. , Sadaka Yair , Freitag Christine M. , Lapidus Keren Mayer , Chiocchetti Andreas G. , Staal Wouter G. , Bohlmeijer Ernst T. 
Published: June 2024

AbstractIntroductionParents of children with a neurodevelopmental disorder (NDD) experience more stress than parents of typically developing children. In a cocreation process with experts and parents, a low-threshold application that uses exercises based on the principles of positive psychology and mindfulness was developed. This application, called “Adappt,” aims at enhancing the ability to adapt of the parents and caregivers of children with NDDs and at supporting their mental health. This protocol describes the evaluation study of the effectiveness of Adappt, its core working mechanisms and user experiences.MethodA pragmatic international multicenter randomized controlled trial will compare the effectiveness of Adappt with a (delayed) waitlist control condition. At least 212 parents or primary caregivers of children younger than 18 years diagnosed with or suspected of a NDD will be randomly assigned to the intervention or waitlist control condition. Participants are excluded if they have severe anxiety or depression levels or are in treatment for mental health issues. Measures will be collected online at baseline, post-intervention (1 month after baseline), and 4 and 7 months after baseline. The primary outcome is the improvement in generic sense of ability to adapt as measured with the Generic Sense of Ability to Adapt Scale (GSAAS; (Front Psychol 14:985408, 2023)) at 4-month follow-up. Secondary outcomes are mental well-being, (parental) distress, and client satisfaction with “Adappt.”DiscussionResults of this study will contribute to knowledge on the effectiveness of a low-threshold application for parents of children with a NDD in multiple countries. If the application is found to be effective in improving mental health, recommendations will be made for implementation in health care.Trial registrationThis study is registered on clinicaltrials.gov (NCT06248762) on February 8, 2024, and the Open Science Framework (https://osf.io/5znqv).
White out hemithorax secondary to salivary gland type of lung cancer with metastasis in liver and bone: a case report
Authors: Badhe Padma V. , Sivakumar M. , Lamture Swastika , Patil Sanika , Tekriwal Khushboo , Mohammad Khalid Ahmad 
Published: June 2024

Abstract
Background
Salivary gland-type lung carcinomas are uncommon neoplasms of the lung, representing less than 1% of all lung tumors. The two most common among them are adenoid cystic carcinoma and mucoepidermoid carcinoma. Although they usually have an indolent behavior, adenoid cystic carcinomas can be more aggressive, with 5-year survival as low as 55%. Very few cases are reported in literature. We report a similar rare case of salivary gland type lung carcinoma that presented for the first time with unilateral opacification of left hemithorax.

Case presentation
A 38-year-old man of North Indian origin, who was a a nonsmoker, presented with complaints of shortness of breath and cough for 1 year, which has increased in the last 2 months and was associated with significant weight loss. A frontal radiograph of the chest and computed tomography of the chest were performed, which showed a mass in the left upper lobe of the lung with its epicenter in the left main bronchus. A bronchoscopic guided biopsy was performed, and histopathology confirmed the diagnosis of lung carcinoma of salivary gland type (adenoid cystic carcinoma). There was invasion of major vessels, hence the patient was offered and started on palliative management instead of surgical treatment.
In spite of palliative management of two cycles of chemotherapy and radiotherapy, the patient succumbed to the disease within 2 months from the time of diagnosis.

Conclusion
Lung carcinoma of the salivary gland type (especially adenoid cystic carcinoma) usually presents at a later stage. The resectability of the tumor depends on the involvement of the surrounding major vessels. Interestingly, these cancers have no association with smoking. The prognosis depends on the extent of the disease at the time of diagnosis. Hence, imaging plays a major role in deciding the further plan of management.
Generalized Tikhonov regularization method for an inverse boundary value problem of the fractional elliptic equation
Authors: Zhang Xiao 
Published: June 2024

AbstractThis research studies the inverse boundary value problem for fractional elliptic equation of Tricomi–Gellerstedt–Keldysh type and obtains a condition stability result. To recover the continuous dependence of the solution on the measurement data, a generalized Tikhonov regularization method based on ill-posedness analysis is constructed. Under the a priori and a posterior selection rules for the regularization parameter, corresponding Hölder type convergence results are obtained. On this basis, this thesis verifies the simulation effect of the generalized Tikhonov method through numerical examples. The examples show that the method performs well in dealing with the problem under consideration.
Hydration Characteristics of Slag-Ca(OH)2-Al2O3 Binder in a 60 °C Curing Environment with Brine as Mixing Water
Authors: Kang Choonghyun , Kim Taewan , Park Yong-Myung , Seo Ki-Young 
Published: June 2024

AbstractRecently, research results on PC-based or alkali-activated slag cement (AASC) using seawater as mixing water have been reported. Unlike seawater, reverse osmosis brine (brine) is waste discharged into the ocean from seawater desalination plants. There is a need to develop new and effective methods of disposing or utilizing brine to reduce marine pollution, protect marine ecosystems, and increase marine plant construction. However, research on cement or concrete using brine as a mixing water is very limited. Brine has almost the same composition as seawater, and the ion concentration is 2–4 times higher. Therefore, it is believed that new methods of using brine can be investigated and developed based on existing research and experimental results on seawater. The effects of brine and aluminum oxide (AO) on activated slag with calcium hydroxide (CH) were investigated for hydration and mechanical properties. 5% and 10% of CH were used, and samples using fresh water (FC) were prepared at the same time for comparison with brine. The slag sample without CH has a low initial (1 and 3d) strength of about 10 MPa for both FC and brine, but increases rapidly from 7d. Incorporation of CH was effective in improving the mechanical performance of FC and brine samples. In addition, the brine sample exhibited higher strength than the FC sample because it formed fewer C3AH6 phases that cause volume instability than the FC sample and affected the hydration promotion of slag particles. And more calcite phases were observed in the brine samples than in the FC samples. Through this study, the possibility of using brine as a building material was confirmed. In addition, the effect of chloride ion adsorption of slag mixed with AO and CH on the physical properties and mechanical performance of the hydration reaction was confirmed.
The impact of 24-h take-home exam on language learning and teaching on the China campus of a British university
Authors: Ye Xiaomin , Yang Yilong , Qie Yi , Hu Zengbao 
Published: June 2024

AbstractTake-home exam (THE) use has been reported in various disciplines, but research on THE use in language modules in higher education appears to be scarce. The current study employed surveys and interviews to examine how the shift to written THE, in place of the traditional in-class exam (ICE) during the pandemic, impacted language learning and teaching on the China campus of a British university. Additionally, correlation analyses were conducted with ranking data of students from the same cohort under THE and ICE to explore patterns in student performance under these exam conditions. In surveys and interviews, teachers reported that their teaching foci did not change under THE, while many students reported that their learning practices were different under THE and ICE. Students also exhibited a tendency to spend more time practicing skills that they expected to be assessed in the exam. Overall, both teachers and students expressed preference for ICE, with many raising concerns about fairness issues in THE. Furthermore, correlation analyses showed that, overall, for a given group of students, written ICE rankings exhibited strong correlations with each other but written THE rankings did not, suggesting relative instability of THE results. However, when written THE and oral ICE results from the same module are combined, the resultant rankings strongly correlated with pure ICE rankings. This indicates that combining ICE and THE components for assessment could help mitigate some perceived shortcomings, including the instability issue, of THE used alone.
Prediction of geothermal temperature field by multi-attribute neural network
Authors: Gao Wanli , Zhao Jingtao 
Published: June 2024

AbstractHot dry rock (HDR) resources are gaining increasing attention as a significant renewable resource due to their low carbon footprint and stable nature. When assessing the potential of a conventional geothermal resource, a temperature field distribution is a crucial factor. However, the available geostatistical and numerical simulations methods are often influenced by data coverage and human factors. In this study, the Convolution Block Attention Module (CBAM) and Bottleneck Architecture were integrated into UNet (CBAM-B-UNet) for simulating the geothermal temperature field. The proposed CBAM-B-UNet takes in a geological model containing parameters such as density, thermal conductivity, and specific heat capacity as input, and it simulates the temperature field by dynamically blending these multiple parameters through the neural network. The bottleneck architectures and CBAM can reduce the computational cost while ensuring accuracy in the simulation. The CBAM-B-UNet was trained using thousands of geological models with various real structures and their corresponding temperature fields. The method’s applicability was verified by employing a complex geological model of hot dry rock. In the final analysis, the simulated temperature field results are compared with the theoretical steady-state crustal ground temperature model of Gonghe Basin. The results indicated a small error between them, further validating the method's superiority. During the temperature field simulation, the thermal evolution law of a symmetrical cooling front formed by low thermal conductivity and high specific heat capacity in the center of the fault zone and on both sides of granite was revealed. The temperature gradually decreases from the center towards the edges.
Engineering extracellular vesicles for ROS scavenging and tissue regeneration
Authors: Abdal Dayem Ahmed , Yan Ellie , Do Minjae , Kim Yoojung , Lee Yeongseo , Cho Ssang-Goo , Kim Deok-Ho 
Published: June 2024

Abstract
Stem cell therapy holds promise for tissue regeneration, yet significant challenges persist. Emerging as a safer and potentially more effective alternative, extracellular vesicles (EVs) derived from stem cells exhibit remarkable abilities to activate critical signaling cascades, thereby facilitating tissue repair. EVs, nano-scale membrane vesicles, mediate intercellular communication by encapsulating a diverse cargo of proteins, lipids, and nucleic acids. Their therapeutic potential lies in delivering cargos, activating signaling pathways, and efficiently mitigating oxidative stress—an essential aspect of overcoming limitations in stem cell-based tissue repair. This review focuses on engineering and applying EVs in tissue regeneration, emphasizing their role in regulating reactive oxygen species (ROS) pathways. Additionally, we explore strategies to enhance EV therapeutic activity, including functionalization and incorporation of antioxidant defense proteins. Understanding these molecular mechanisms is crucial for optimizing EV-based regenerative therapies. Insights into EV and ROS signaling modulation pave the way for targeted and efficient regenerative therapies harnessing the potential of EVs.
Toward automated microstructure characterization of stainless steels through machine learning-based analysis of replication micrographs
Authors: Ghauri Hamza , Tafreshi Reza , Mansoor Bilal 
Published: June 2024

AbstractMachine learning-driven automated replication micrographs analysis makes possible rapid and unbiased damage assessment of in-service steel components. Although micrographs captured by scanning electron microscopy (SEM) have been analyzed at depth using machine learning, there is no literature available on the technique being attempted on optical replication micrographs. This paper presents a machine-learning approach to segment and quantify carbide precipitates in thermally exposed HP40-Nb stainless-steel microstructures from batches of low-resolution optical images obtained by replication metallography. A dataset of nine micrographs was used to develop a random forest classification model to segment precipitates within the matrix (intragranular) and at grain boundaries (intergranular). The micrographs were preprocessed using background subtraction, denoising, and sharpening to improve quality. The method achieves high segmentation accuracy (91% intergranular, 97% intragranular) compared to human expert classification. Furthermore, segmented micrographs were quantified to obtain carbide size, shape, and density distribution. The correlations in the quantified data aligned with expected carbide evolution mechanisms. Results from this study are promising but necessitate validation of the method on a larger dataset representative of evolution of thermal degradation in steel, given that characterization of the evolution of microstructure components, such as precipitates, applies to broad applications across diverse alloy systems, particularly in extreme service.
A case of chronic expanding hematoma mimicking a cystic pancreatic tumor
Authors: Sakamoto Asuna , Ando Yasuhisa , Feng Dongping , Nagao Mina , Matsukawa Hiroyuki , Nishiura Bunpei , Kondo Akihiro , Suto Hironobu , Asano Eisuke , Kishino Takayoshi , Oshima Minoru , Kumamoto Kensuke , Okano Keiichi 
Published: June 2024

Abstract
Background
A chronic expanding hematoma is an uncommon entity described as an organized blood collection that increases in size after the initial hemorrhagic event without histological neoplastic features. The standard treatment is complete resection. To our knowledge, this is the first report of a chronic expanding hematoma mimicking a pancreatic cystic tumor that has been successfully resected utilizing a laparoscopic approach.

Case presentation
We report the case of a 32-year-old man with a 10-cm chronic expanding hematoma that was preoperatively diagnosed as a cystic pancreatic tumor. Dynamic computed tomography revealed a cyst at the inferior part of the uncinate process of the pancreas without contrast enhancement. His blood biochemical data were within normal limits. The operation initially utilized a laparoscopic approach; however, the procedure was converted to hand-assisted laparoscopic surgery due to capsule adherence to surrounding organs and finally, enucleation of the tumor was performed. Pathological findings revealed a chronic expanding hematoma in the retroperitoneal space.

Conclusion
Chronic expanding hematoma in the retroperitoneal space is so rare and sometimes adheres to the surrounding tissue. It is difficult to distinguish hematoma attaching pancreas and pancreatic cyst preoperatively. In rare cases such as this, hand-assisted laparoscopic surgery is a feasible, less invasive procedure for facilitating complete resection and preventing recurrence.
Participants’ perceived benefits from the GLA:D™ program for individuals living with hip and knee osteoarthritis: a qualitative study
Authors: Kania-Richmond Ania , Beaupre Lauren A. , Jessiman-Perreault Geneviève , Tribo Danika , Martyn Jason , Hart David A. , Robert Jill , Slomp Mel , Jones C. Allyson 
Published: June 2024

Abstract
Background
The Good Life with osteoArthritis: Denmark (GLA:D™), an evidence-based education and exercise program designed for conservative management of knee and hip osteoarthritis (OA), has been shown to benefit participants by reducing pain, improving function, and quality of life. Standardized reporting in the GLA:D databases enabled the measurement of self-reported and performance-based outcomes. There is a paucity of qualitative research on the participants’ perceptions of this program, and it is important to understand whether participants’ perceptions of the benefits of the program align with reported quantitative findings.

Methods
We conducted semi-structured telephone interviews with individuals who participated in the GLA:D program from January 2017 to December 2018 in Alberta, Canada. Data were analyzed using an interpretive description approach and thematic analysis to identify emergent themes and sub-themes associated with participants perceived benefits of the GLA:D program. We analyzed the data using NVivo Pro software. Member checking and bracketing were used to ensure the rigour of the analysis.

Results
30 participants were interviewed (70% female, 57% rural, 73% knee OA). Most participants felt the program positively benefited them. Two themes emerged from the analysis: wellness and self-efficacy. Participants felt the program benefited their wellness, particularly with regard to pain relief, and improvements in mobility, strength, and overall well-being. Participants felt the program benefited them by promoting a sense of self-efficacy through improving the confidence to perform exercise and routine activities, as well as awareness, and motivation to manage their OA symptoms. Twenty percent of participants felt no benefits from the program due to experiencing increased pain and feeling their OA was too severe to participate.

Discussion
The GLA:D program was viewed as beneficial to most participants, this study also identified factors (e.g., severe OA, extreme pain) as to why some participants did not experience meaningful improvements. Early intervention with the GLA:D program prior to individuals experiencing severe OA could help increase the number of participants who experience benefits from their participation.

Conclusion
As the GLA:D program expands across jurisdictions, providers of the program may consider recruitment earlier in disease progression and targeting those with mild and moderate OA.
Do board characteristics matter in the relationship between intellectual capital efficiency and firm value? Evidence from the Nigerian oil and gas downstream sector
Authors: Bala Ahmed Jinjiri , Hassan Aminu , Muhammad Muhammad Liman 
Published: June 2024

Abstract
Purpose
The purpose of this study is to investigate the moderating effects of board characteristics such as board size, chief executive officer duality, number of board meetings, and diversity, on the relationship between intellectual capital efficiency and firm value in the Nigerian oil and gas downstream sector.

Design/methodology/approach
We collected time-series cross-sectional data from eight (8) downstream-sector oil and gas companies quoted on the Nigerian Exchange Group for the period 2004–2020. We analysed the data using Prais–Winsten regression with panel-corrected standard errors.

Findings
Overall, our results show no significant direct relationship between the modified value-added intellectual coefficient and our two measures of firm value (Tobin’s Q and Price Earnings Ratio (PER)). However, the board size is found to moderate the intellectual capital efficiency–PER relationship significantly and negatively, whereas board diversity significantly positively moderates the association between the modified value-added intellectual coefficient and PER. Our multi-theory framework, which blends clean surplus, agency, stakeholder, and resource-based theories is found to be relevant in underpinning this study.

Research limitations/implications
The research relies on 17-year panel data for eight downstream-sector oil and gas companies. Consequently, future research within intellectual capital efficiency in Nigeria could incorporate related sectors like midstream and upstream to enable comparability and expand generalization.

Practical implication
Policymakers may adopt the study findings to serve as a robust empirical base to demand improved board diversity as a catalyst for boosting the potency of the intellectual capital efficiency-firm value relationship.

Originality/value
Firstly, to the best of our knowledge, this study is the pioneer attempt to use board characteristics as moderators of the relationship between intellectual capital efficiency and firm value. Secondly, we develop and use a novel theoretical framework that combines clean surplus, agency, stakeholder, and resource-based theories to underpin the study.