bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Problems of UNP College Freshmen Student Boarders and Their Impact on their Academic Performance
Authors: Concepcion B. Azares  , Gertrudes C. Cabebe  
Published: July 2024

The study Investigated on the common problems of the UNP College student boarders in terms of conditions like: physical/environmental, social and psychological, as well as economic, and all those relative to their living quarters away from home. Focusing on College Freshmen student boarders, attempted to assess the impact of their problems to their academic performance. House facilities and location of boarding houses significantly affected the students' academic achievement while structure and cleanliness/sanitation had no significant effect to the same. The relationship between boarders and landlady/landlord together with problems relative to policies and regulations of boarding houses significantly affected their academic achievement. Other conditions with significant effects were good services which were not usually satisfactory. Hopefully, this study assists the university administration in its formulation of student services for their welfare and development as well as owners/proprietors of boarding houses and dormitories for the improvement of conditions in these living quarters for the vetterment of students' academic performance.
Pengaruh Model Pembelajaran Complete Sentence terhadap Kemampuan Menulis Teks Berita
Authors: Sihombing Shinta Uly Monalisa , Sitohang Tigor , Panggabean Sarma 
Published: July 2024

The purpose of this research is to develop reading materials using digital media. The advantage of this research is that the use of digital media as a learning tool can be used as a reference in providing alternative reading materials that suit the needs of students. This activity involves analyzing and organizing complex skills such as learning, thinking, reasoning, assimilation, and problem solving. First, the media as a support for learning, and the second is the media as a source of learning. Reading Indonesian texts for foreign speakers presents its own challenges in learning it. Reading has several skills that must be mastered. The habit of practicing reading greatly help you improve your reading skills. Using digital media can improve word reading skills. You should also be able to interpret and understand the words in the text.
Keywords: reading, teaching materials, curriculum, development
Model pembelajaran complete sentence adalah model pembelajaran yang dapat meningkatkan kemampuan siswa dalam menulis teks berita karena menuntut siswa untuk mengaitkan informasi yang satu dengan yang lainnya. Penelitian ini dilakukan untuk mengetahui pengaruh model pembelajaran complete sentence terhadap kemampuan siswa menulis teks berita. Penelitian ini menggunakan metode penelitian kuantitatif eksperimen dengan menguji data nilai siswa pada kelas eksperimen dan kelas kontrol. Hasil dari penelitian ini menunjukan bahwa model complete sentence berpengaruh terhadap kemampuan menulis teks berita siswa hal tersebut dibuktikan dengan rata-rata nilai siswa pada kelas eksperimen lebih tinggi daripada kelas kontrol yaitu rata-rata untuk kelas eksperimen sebesar 70,2 dan rata-rata kelas kontrol sebesar 45,06.
Kata Kunci: model complete sentence, teks berita, kemampuan menulis.
The Features of Tea Packaging Design in China
Authors: Yu Beibei 
Published: July 2024

The object of the study is the design of tea packaging in China. The subject of the study is the problem of the formation of a national features in the design of tea packaging in China. During the research, such issues as the brief history of the subject of research, the specifics of the modern view of tea packaging in China, the main factors in the formation of approaches to the development and design of tea packaging with national specifics, the concept of a "cultural and creative product" are traced. The problem of integrating elements of traditional culture and aesthetics into the sphere of modern design of tea packaging products is considered separately. In addition, an analysis of examples of successful design is given, in which the competent and effective use of cultural tradition is traced. The advantages of using one's own tea packaging language as a product promotion factor are revealed. The study involves the systematization of available information on the theory and history of tea packaging design in China. An integrated approach is used to create a holistic view of the formation of China's own design language for these products. The scientific novelty of the study is due to the fact that for the first time a complex of issues related to the problem of forming a national language in tea packaging design in China is being studied. Individual samples of modern Chinese tea packaging design are being introduced into scientific circulation. The author's main contribution to the research of the topic is to identify the grounds that determine the features of the process of developing one's own language in tea packaging design in China at the present stage. The main conclusions of the study: currently, the formation of China's own tea packaging language is associated with the actualization of cultural tradition and spiritual heritage, which is associated with the orientation of tea producers not only to the Chinese consumer, but also to a foreign audience. The development of a national language in the design of tea packaging has the character of adapting traditional culture and aesthetics, the principles of which are determined by the concept of a "cultural and creative product".
Assessment of Knowledge Management Strategies on Performance of Kenya Marine and Fisheries Research Institute
Authors: Kioko Josephine , Muriuki Jennifer 
Published: July 2024

The study determined the influence of knowledge management strategies on the performance of Kenya Marine and Fisheries Research Institute. The study objectives were to determine how knowledge acquisition, storage, expertise (Technology) and accessibility influence the performance of Kenya Marine and Fisheries Research Institute. The study was guided by Resource-Based View (RBV), Knowledge-Based View (KBV), Dynamic Capabilities Theory (DCT) and Social Exchange Theory (SET). Since the study involved gathering of quantitative and qualitative data, it adopted mixed method approach. The study employed a descriptive survey research design, this was due to the prediction of knowledge management strategies and the performance Kenya Marine and Fisheries Research Institute, in the analysis of different trends, and the formulation of hypotheses that directs future actions. The target population was 168 employees from the Kenya Marine and Fisheries Research Institute. The researcher sampled 118 respondents using Yamane formula (2007) formula, by doing so, the chance of bias in participant selection was reduced and the sample was guaranteed to be representative of the whole population.Data was analyzed using descriptive statistics in the form of means, percentages, and frequencies with help of Statistical Package for Social Sciences v25 (SPSS V25) software. Results were displayed in form of pie chart and tables from which inferences and conclusions were drawn. The findings of the study revealed that knowledge sharing had the most significant influence on the performance of Kenya Marine and Fisheries Research Institute while knowledge acquisition had the least influence on performance of Kenya Marine and Fisheries Research Institute. The research finally concluded that knowledge management strategies had a significant effect on the performance of Kenya Marine and Fisheries Research Institute.
Measurement of Phagocytic Engulfment of Apoptotic Cells by Macrophages Using pHrodo Succinimidyl Ester
Authors: Aziz Monowar , Yang Weng‐Lang , Wang Ping 
Published: February 2013

AbstractConsiderable interest has emerged towards phagocytosis of apoptotic cells, due to its intricate molecular mechanisms and important regulatory functions in development, homoeostasis, and immune tolerance. Impaired clearance of apoptotic cells leads to immune‐mediated disorders. Current quantification methods of the engulfment of apoptotic cells by macrophages are potentially flawed by several limitations. Adherent macrophage populations are overlaid with apoptotic targets in suspension and then co‐cultured for a definite period, which may give rise to two different features: (1) engulfed and (2) non‐engulfed macrophages that are surface‐bound cell populations. Rigorous washing to dislodge surface‐bound apoptotic cells before assessment of phagocytosis may lead to loss of phagocytes, thereby skewing the apparent magnitude of the overall phagocytic response. There is a need for simple and reliable methods to clearly determine the internalization of apoptotic cells. In this unit, we demonstrate the use of pHrodo‐succinimidyl ester (SE), a pH‐sensitive fluorescent dye, to label the apoptotic cells for monitoring the phagocytosis. After engulfment, the intensity of pHrodo light emission will be elevated due to the pH change inside of macrophages. The shift of pHrodo light emission can be detected by a flow cytometer or using a fluorescence microscope. Curr. Protoc. Immunol. 100:14.31.1‐14.31.8. © 2013 by John Wiley & Sons, Inc.
Comparing Individual NK Cell Activity In Vitro
Authors: Sierich Heidi , Eiermann Thomas 
Published: February 2013

AbstractNatural killer (NK) cells play an important role in the innate immune system by eliminating infected and mutated cells. Their cytotoxic capacities vary markedly among individuals. The cytotoxic activity can be measured in peripheral blood mononuclear cells (PBMCs) using the NK cell–specific target cell line K562. In this chapter, we present a protocol for the standardization and normalization of cell preparation and NK cell cytotoxicity measurement in a 51Cr‐release assay. By following these protocols, it is possible to compare the NK cell activity of numerous—if necessary selected—individuals in vitro. Curr. Protoc. Immunol. 100:14.32.1‐14.32.11. © 2013 by John Wiley & Sons, Inc.
Chameleon Nonwovens by Green Electrospinning
Authors: Giebel Elisabeth , Mattheis Claudia , Agarwal Seema , Greiner Andreas 
Published: February 2013

AbstractElectrospun ionic nonwovens are obtained by green electrospinning of aqueous dispersions. The resulting nonwovens are termed as chameleon nonwovens since their surface properties can be tailored in a large variety by coating of different functionalities following the protocol of the layer‐by‐layer process (LBL). The dimensional stability of the electrospun fibers in the chameleon nonwovens is achieved by photo‐cross‐linking after electrospinning and thereby overcoming the repulsive forces of the ionic moieties in the fibers. Depending on the nature of the ionic moieties different materials are coated by LBL including dyes, antibacterial materials, silver, and gold nanoparticles. Enhanced coating efficiency for coating of metal nanoparticles is observed when the chameleon nonwovens were precoated by a polyelectrolyte.
Development of 3D hydrogel culture systems with on‐demand cell separation
Authors: Hamilton Sharon K. , Bloodworth Nathaniel C. , Massad Christopher S. , Hammoudi Taymour M. , Suri Shalu , Yang Peter J. , Lu Hang , Temenoff Johnna S. 
Published: February 2013

AbstractRecently there has been an increased interest in the effects of paracrine signaling between groups of cells, particularly in the context of better understanding how stem cells contribute to tissue repair. Most current 3D co‐culture methods lack the ability to effectively separate two cell populations after the culture period, which is important for simultaneously analyzing the reciprocal effects of each cell type on the other. Here, we detail the development of a 3D hydrogel co‐culture system that allows us to culture different cell types for up to 7 days and subsequently separate and isolate the different cell populations using enzyme‐sensitive glues. Separable 3D co‐culture laminates were prepared by laminating PEG‐based hydrogels with enzyme‐degradable hydrogel adhesives. Encapsulated cell populations exhibited good segregation with well‐defined interfaces. Furthermore, constructs can be separated on‐demand upon addition of the appropriate enzyme, while cell viability remains high throughout the culture period, even after laminate separation. This platform offers great potential for a variety of basic cell signaling studies as the incorporation of an enzyme‐sensitive adhesive interface allows the on‐demand separation of individual cell populations for immediate analysis or further culture to examine persistence of co‐culture effects and paracrine signaling on cell populations.See accompanying commentary by Danielle R. Bogdanowicz and Helen H. Lu DOI: 10.1002/biot.201300054
Development and validation of a highly sensitive LC‐ESI‐MS/MS method for the determination of hyperoside in beagle dog plasma: application to a pharmacokinetic study
Authors: Yin Xingbin , Li Zhaoxia , Zhai Yujing , Zhang Hui , Lin Longfei , Yang Pei , Cao Sali , Zhang Jin , Qi Juanjuan , Tian Jingchen , Fu Jing , Qu Changhai , Ni Jian 
Published: February 2013

ABSTRACTA highly sensitive, rapid assay method has been developed and validated for the analysis of hyperoside in beagle dog plasma with liquid chromatography coupled to tandem mass spectrometry with electrospray ionization in the positive‐ion mode. The assay procedure involves extraction of hyperoside and ginsenoside Re (IS) from beagle dog plasma. Chromatographic separation was carried out on an Agilent Zorbax XDB‐C18 (100 × 2.1 mm, 1.8 µm) column by isocratic elution with acetonitrile and water (50:50, v/v) at a flow rate of 0.25 mL/min with a total run time of 2.0 min. The MS/MS ion transitions monitored were 464.4 → 463.4 for hyperoside and 947.12 → 969.60 for IS. Linear responses were obtained for hyperoside ranging from 10 to 5000 ng/mL. The intra‐and inter‐day precisions (RSDs) were <5.38 and 3.39% and the extraction recovery ranged from 94.39 to 100.78% with an RSD <3.82%. Stability studies showed that hyperoside was stable in preparation and analytical process. The results indicated that the validated method was successfully used to determine the concentration–time profiles of hyperoside. Copyright © 2013 John Wiley & Sons, Ltd.
Surface Segregation of Pd from TiO2‐Supported AuPd Nanoalloys under CO Oxidation Conditions Observed In situ by ETEM and DRIFTS
Authors: Delannoy Laurent , Giorgio Suzanne , Mattei Jean Gabriel , Henry Claude R. , El Kolli Nadia , Méthivier Christophe , Louis Catherine 
Published: February 2013

AbstractA TiO2‐supported AuPd bimetallic catalyst with an Au/Pd atomic ratio of 8 was prepared by deposition‐precipitation with urea, and its activity in CO oxidation at room temperature was compared to the one of a monometallic Au/TiO2 catalyst. X‐ray photoelectron spectroscopy (XPS) and diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS) analyses suggest that Au‐Pd/TiO2 contains bimetallic nanoparticles after reduction under H2 at 500 °C although the presence of monometallic Au particles cannot be totally excluded. The evolution of the AuPd nanoparticles surface composition during exposure to O2 and CO/O2 was studied in situ by environmental high resolution electron microscopy (ETEM) and DRIFTS. Pd segregation at the surface of the bimetallic nanoparticles was evidenced by DRIFTS and directly observed by ETEM under O2 and CO/O2 with the formation of Aucore‐Pdshell structure. The changes in the surface composition of the Au‐Pd nanoparticles under CO/O2 was paralleled with the higher rate of deactivation in the first reaction stages observed for Au‐Pd/TiO2 compared to Au/TiO2, which could be related to the possible replacement of Au in low coordination sites, at the origin of the high activity in CO oxidation, by Pd atoms. These results noticeably underline the modifications induced by the reactant that can undergo a bimetallic AuPd catalyst.
Combination of Black‐Light Photo‐catalysis and Ozonation for Emerging Contaminants Degradation in Secondary Effluents
Authors: Encinas Á. , Rivas F. J. , Beltrán F. J. , Oropesa A. 
Published: February 2013

AbstractA water solution of emerging contaminants (ECs) was treated by advanced oxidation systems. Ozone‐based processes led to the highest ECs degradation rates. Regardless of the nature of the aqueous matrix, no differences in EC removal were obtained when O3 was added. Mineralization occurred to some extent when activated carbon (AC) or O3 were present. O3, UVA/TiO2/O2, and UVA/TiO2/O3 processes were applied in runs carried out with low ECs concentration. Single ozonation and photocatalytic ozonation led to the complete ECs degradation in less than 5 min. When a secondary effluent was used, the efficiency of the technologies decreased. With the exception of caffeine, a detrimental effect of other organic/inorganic compounds present in secondary effluents was observed.
Polyphenole: Vielseitige Pflanzeninhaltsstoffe
Authors: Kuhnert Nikolai 
Published: February 2013

AbstractAlle Pflanzen stellen Polyphenole her, die sowohl strukturell als auch in ihren chemischen und biologischen Eigenschaften eine faszinierende Vielfalt zeigen. Während den pflanzlichen Organismen Polyphenole als UV‐Lichtschutz, als chemische Verteidigung gegen Mikroorganismen und Pflanzenfresser dienen und durch ihre Färbung Insekten anlocken, nutzen Menschen ihre Eigenschaften in industriellen Prozessen, dabei vor allem zur Verbesserung unserer Gesundheit. Polyphenole sind sowohl als Bestandteil unserer täglichen Nahrung als auch als Bestandteil traditioneller Arzneipflanzen in der Lage, in vielfältiger Weise mit den biochemischen Strukturen des menschlichen Stoffwechsels zu interagieren und Symptome wie auch Ursachen vieler Erkrankungen zu beeinflussen. Die Wirkung der Polyphenole als Antioxidantien, die viele Jahre lang zur Erklärung der gesundheitsförderlichen Eigenschaften der Polyphenole herangezogen wurde, ist nach neuesten Erkenntnissen in den Hintergrund getreten. Neue Ansätze zur Erklärung der biologischen Eigenschaften der Polyphenole haben sich in den letzten Jahren entwickelt, die die chemischen Veränderungen der Polyphenole durch Lebensmittelprozessierung und Metabolismus berücksichtigen und sich nur auf Verbindungen konzentrieren, die gut bioverfügbar sind. Die Verstoffwechselung und die Wirkweise der Polyphenole im menschlichen Körper hat sich in den letzten Jahren als komplizierter erwiesen als lange angenommen. Eine klare Antwort auf die Frage, welche Verbindungen gesund sind und wie diese wirken, ist erneut Gegenstand aktueller Forschung geworden.
Novel Schiff‐Base‐Derived FabH Inhibitors with Dioxygenated Rings as Antibiotic Agents
Authors: Zhou Yang , Du Qian‐Ru , Sun Jian , Li Jing‐Ran , Fang Fei , Li Dong‐Dong , Qian Yong , Gong Hai‐Bin , Zhao Jing , Zhu Hai‐Liang 
Published: February 2013

AbstractFatty acid biosynthesis plays a vital role in bacterial survival and several key enzymes involved in this biosynthetic pathway have been identified as attractive targets for the development of new antibacterial agents. Of these promising targets, β‐ketoacyl‐acyl carrier protein (ACP) synthase III (FabH) is the most attractive target that could trigger the initiation of fatty acid biosynthesis and is highly conserved among Gram‐positive and ‐negative bacteria. Designing small molecules with FabH inhibitory activity displays great significance for developing antibiotic agents, which should be highly selective, nontoxic and broad‐spectrum. In this manuscript, a series of novel Schiff base compounds were designed and synthesized, and their biological activities were evaluated as potential inhibitors. Among these 21 new compounds, (E)‐N‐((3,4‐dihydro‐2H‐benzo[b][1,4]dioxepin‐7‐yl)methylene)hexadecan‐1‐amine (10) showed the most potent antibacterial activity with a MIC value of 3.89–7.81 μM−1 against the tested bacterial strains and exhibited the most potent E. coli FabH inhibitory activity with an IC50 value of 1.6 μM. Docking simulation was performed to position compound 10 into the E. coli FabH active site to determine the probable binding conformation.
Localized and metastatic myxoid/round cell liposarcoma
Authors: Hoffman Aviad , Ghadimi Markus P. H. , Demicco Elizabeth G. , Creighton Chad J. , Torres Keila , Colombo Chiara , Peng Tingsheng , Lusby Kristelle , Ingram Davis , Hornick Jason L. , Wang Wei‐Lie , Ravi Vinod , Lazar Alexander J. , Lev Dina , Pollock Raphael E. 
Published: February 2013

AbstractBACKGROUND.Myxoid liposarcoma (MLPS), a disease especially of young adults with potential for local recurrence and metastasis, currently lacks solid prognostic factors and therapeutic targets. The authors of this report evaluated the natural history and outcome of patients with MLPS and commonly deregulated protein biomarkers.METHODS.Medical records were retrospectively reviewed for patients who presented to the authors' institution with localized (n = 207) or metastatic (n = 61) MLPS (1990 to 2010). A tissue microarray of MLPS patient specimens (n = 169) was constructed for immunohistochemical analysis of molecular markers.RESULTS.The 5‐year and 10‐year disease‐specific survival rates among patients with localized disease were 93% and 87%, respectively; male gender, age >45 years, and recurrent tumor predicted poor outcome. The local recurrence rate was 7.4%, and the risk of local recurrence was associated with recurrent tumors and nonextremity disease location. Male gender was the main risk factor for metastatic disease, which occurred in 13% of patients. Forty percent of patients who had localized disease received chemotherapy, mostly in the neoadjuvant setting. Immunohistochemical analysis revealed significantly higher expression of C‐X‐C chemokine receptor type 4 (CXCR4) and platelet‐derived growth factor beta (PDGFR‐β) in metastatic lesions versus localized lesions. Tumors with a round cell phenotype expressed increased levels of CXCR4, p53, adipophilin, PDGFR‐α, PDGFR‐β, and vascular endothelial growth factor relative to myxoid phenotype. Only the receptor tyrosine kinase encoded by the AXL gene (AXL) was identified as a prognosticator of disease‐specific survival in univariate analysis.CONCLUSIONS.In this study, the authors identified clinical and molecular outcome prognosticators for patients with MLPS as well as several potential therapeutic targets. Cancer 2013. © 2013 American Cancer Society.