bluuebunny/crossref_metadata_2025_split huggingface dataset:
Novel hawk swarm‐optimized deep learning classification with K‐nearest neighbor based decision making for autonomous vehicle movement controller
Authors: Qingmiao Zhang , Dinghua Zhang 
Published: August 2024

SummaryNowadays, intelligent transportation systems pay a lot of attention to autonomous vehicles it is believed that an autonomous vehicle improves mobility, comfort, safety, and energy efficiency. Making decisions is essential for the development of autonomous vehicles since these algorithms must be able to manage dynamic and complex urban crossings. In this research an optimal deep BiLSTM‐GAN classifier to detect the movement of smart vehicles, initially the preprocessing stage is performed to decrease noise in the received data after that the essential regions are next be extracted in the region of interest (ROI) to make the right decision. The extracted data are forwarded to the GAN for road segmentation as well as the optimized deep BiLSTM classifier, which recognizes the traffic sign, simultaneously making it possible to do a modified Hough line‐based maneuver prediction using the segmented information from the roads. Finally, the GAN determines the lane, and the BiLSTM predicts the traffic sign. The K‐nearest neighbor (KNN)‐based autonomous vehicle movement controllers are used to make the decision based on the predicted traffic sign and information about the lane. The proposed HSO algorithm was developed as the outcome of the common fusion of hawk and swarm optimization. Based on lane detecting achievements, at training percentage (TP) 90, the accuracy is 91.75%, Peak signal‐to‐noise ratio (PSNR) is 64.84%, mean square error (MSE) is 28.78, and mean absolute error (MAE) is 20.20, respectively, similarly based on the traffic sign prediction achievements at TP 90, the accuracy is 93.71%, sensitivity is 95.15%, specificity is 93.91%, and MSE is 28.78%, respectively.
Enhancing organizational attractiveness through CSR consistency: Examining the impact of corporate hypocrisy, conceptual fluency, and proactive communication in HR recruitment
Authors: Li Hong‐yan , Duan Xianxian , Fu Qiang 
Published: August 2024

AbstractIncorporating corporate social responsibility (CSR) into organizational strategies has become essential, demonstrating a dedication to ethical conduct and sustainable practices. This paper investigates how consistency in CSR practices impacts organizational attractiveness. Drawing upon the theory of the continuum model of impression formation, two separate studies were undertaken to investigate the influence of CSR consistency (both consistent and inconsistent CSR) on the appeal of organizations. Besides, these studies aimed to evaluate the mediating roles of conceptual fluency and perceived corporate hypocrisy in this relationship, as well as the moderating effect of two corporate communication strategies (proactive and passive). The study found that perceptions of corporate hypocrisy played a significant mediating role in the link between inconsistent CSR practices and the appeal of an organization. This mediating effect was diminished by the use of proactive communication strategies. In contrast, conceptual fluency was identified as a key mediator in the relationship between consistent CSR practices and organizational attractiveness, with its mediating effect being enhanced by proactive communication strategies. This study makes a novel contribution by focusing on the temporal stability of CSR initiatives and broadens the understanding of whether sustained engagement in CSR activities over time confers greater organizational attractiveness than occasional or random initiatives. This study extends the theory of the relationship between perceived CSR and job seekers and provides guidance and recommendations for CSR activities and HR recruitment practices for companies in the post‐epidemic era.
Recent Advances in Engineering Fe−N−C Catalysts for Oxygen Electrocatalysis in Zn‐Air Batteries
Authors: Li Le , Han Meijun , Zhang Penggang , Yang Donglei , Zhang Meng 
Published: August 2024

AbstractFe−N−C single‐atom catalysts (SACs) have emerged as one of the most promising candidates for oxygen electrocatalysis due to their maximized atom utilization efficiency, high intrinsic activity, and strong metal‐support interaction. Significant progress has been made in engineering Fe−N−C SACs for oxygen electrocatalysis in Zn‐air batteries (ZABs). This review provides a comprehensive overview of the recent advancements in Fe−N−C SACs, with a special focus on effective engineering strategies, their performance in oxygen electrocatalysis, and their potential applications in ZABs. The review also discusses the key challenges and future directions in the development of Fe−N−C SACs for efficient and durable oxygen electrocatalysis in ZABs. This review aims to offer valuable insights into the current state of research in this field and to guide future efforts in the development of advanced oxygen electrocatalysts for ZABs.
Vanadium‐Doped Ni3S2: Morphological Evolution for Enhanced Industrial‐Scale Water and Urea Electrolysis
Authors: Sharma Pooja J. , Joshi Kinjal K. , Siraj Sohel , Sahatiya Parikshit , Sumesh C. K. , Pataniya Pratik M. 
Published: August 2024

AbstractThe development of an earth abundant, cost‐effective, facile and multifunctional 3D‐porous catalytic network for green hydrogen production is a tremendous challenge. Herein, we report the V‐Ni3S2 self‐supported catalytic network with optimized morphology grown directly on nickel foam (NF) by the one‐step hydrothermal technique for water and urea electrolysis at industrial scale hydrogen generation. The morphology of Ni3S2 was modulated by doping of different concentrations of vanadium from granules to cross‐linked wires to hierarchal nanosheets arrays, which is beneficial in electrochemical charge and mass transport, and generates more exposed active sites. The V‐Ni3S2 catalyst requires the overpotential of 147 mV for hydrogen evolution reaction (HER). The OER and UOR half‐cell reaction on V‐Ni3S2 catalyst requires potential 1.57 V and 1.39 V (vs RHE), respectively to generate current 100 mA/cm2. The water electrolysis cell developed by V‐Ni3S2 as both anode and cathode generates 100 mA/cm2 at cell voltage of 1.88 V in laboratory condition (1 M KOH, 25 °C) and 1.61 V at industrial condition (5 M KOH, 80 °C) and also shows considerable stability for 82 hr at current 300 mA/cm2. The urea electrolysis cell with 1 M KOH and 0.33 M urea generates 100 mA/cm2 at a cell voltage of 1.73 V, which is 150 mV less than that required for water electrolysis and demonstrate stability for 85 hr at a current of 100 mA/cm2. The results provide an innovative plan for the considerate synthesis and design of bifunctional catalysts for energy storage and water splitting.
Complete organelle genomes of the threatened aquatic species Scheuchzeria palustris (Scheuchzeriaceae): Insights into adaptation and phylogenomic placement
Authors: He Xiang‐Yan , Chen Jin‐Ming , Li Zhi‐Zhong 
Published: August 2024

AbstractScheuchzeria palustris, the only species in the Scheuchzeriaceae family, plays a crucial role in methane production and transportation, influencing the global carbon cycle and maintaining ecosystem stability. However, it is now threatened by human activities and global warming. In this study, we generated new organelle genomes for S. palustris, with the plastome (pt) measuring 158,573 bp and the mitogenome (mt) measuring 420,724 bp. We predicted 296 RNA editing sites in mt protein‐coding genes (PCGs) and 142 in pt‐PCGs. Notably, abundant RNA editing sites in pt‐PCGs likely originated from horizontal gene transfer between the plastome and mitogenome. Additionally, we identified positive selection signals in four mt‐PCGs (atp4, ccmB, nad3, and sdh4) and one pt‐PCG (rps7), which may contribute to the adaptation of S. palustris to low‐temperature and high‐altitude environments. Furthermore, we identified 35 mitochondrial plastid DNA (MTPT) segments totaling 58,479 bp, attributed to dispersed repeats near most MTPT. Phylogenetic trees reconstructed from mt‐ and pt‐PCGs showed topologies consistent with the APG IV system. However, the conflicting position of S. palustris can be explained by significant differences in the substitution rates of its mt‐ and pt‐PCGs (p < .001). In conclusion, our study provides vital genomic resources to support future conservation efforts and explores the adaptation mechanisms of S. palustris.
Beta‐blocker use and outcomes in patients with heart failure and mildly reduced and preserved ejection fraction
Authors: Matsumoto Shingo , Henderson Alasdair D. , Shen Li , Kondo Toru , Yang Mingming , Campbell Ross T. , Anand Inder S. , de Boer Rudolf A. , Desai Akshay S. , Lam Carolyn S.P. , Maggioni Aldo P. , Martinez Felipe A. , Packer Milton , Redfield Margaret M. , Rouleau Jean L. , Van Veldhuisen Dirk J. , Vaduganathan Muthiah , Zannad Faiez , Zile Michael R. , Jhund Pardeep S. , Solomon Scott D. , McMurray John J.V. 
Published: August 2024

ABSTRACTAimsIn the absence of randomized trial evidence, we performed a large observational analysis of the association between beta‐blocker (BB) use and clinical outcomes in patients with heart failure (HF) and mildly reduced (HFmrEF) and preserved ejection fraction (HFpEF).Methods and resultsWe pooled individual patient data from four large HFmrEF/HFpEF trials (I‐Preserve, TOPCAT, PARAGON‐HF, and DELIVER). The primary outcome was the composite of cardiovascular death or HF hospitalization. Among the 16 951 patients included, the mean left ventricular ejection fraction (LVEF) was 56.8%, and 13 400 (79.1%) had HFpEF (LVEF ≥50%). Overall, 12 812 patients (75.6%) received a BB. The median bisoprolol‐equivalent dose of BB was 5.0 (Q1–Q3: 2.5–5.0) mg with BB continuation rates of 93.1% at 2 years (in survivors). The unadjusted hazard ratio (HR) for the primary outcome did not differ between BB users and non‐users (HR 0.98, 95% confidence interval [CI] 0.91–1.05), but the adjusted HR was lower in BB users than non‐users (0.81, 95% CI 0.74–0.88), and this association was maintained across LVEF (pinteraction = 0.88). In subgroup analyses, the adjusted risk of the primary outcome was similar in BB users and non‐users with or without a history of myocardial infarction, hypertension, or a baseline heart rate <70 bpm. By contrast, a better outcome with BB use was seen in patients with atrial fibrillation compared to those without atrial fibrillation (pintreraction = 0.02).ConclusionsIn this observational analysis of non‐randomized BB treatment, there was no suggestion that BB use was associated with worse HF outcomes in HFmrEF/HFpEF, even after extensive adjustment for other prognostic variables.
Shelf‐life extension of fresh mushrooms: From conventional practices to novel technologies—A comprehensive review
Authors: Sharma Vaibhav , Singh Poornima , Singh Anurag 
Published: August 2024

AbstractMushroom is an edible fungus grown worldwide because of its nutritional and commercial value. The demand for mushrooms is rising annually because of increased awareness of the dietary benefits of mushrooms. Mushrooms are a perishable commodity as they respire continuously after harvesting. Adequate packaging or processing is required to increase mushrooms' shelf life. The quality of mushrooms continues to decline after harvesting, including browning, moisture loss, texture changes, increased bacteria, and loss of flavor and nutrients. Postharvest preservation methods, including physical, chemical, and thermal treatments, are necessary to preserve postharvest quality and increase the shelf life of mushrooms. The postharvest technology of mushrooms must be improved to fulfill the increasing demand for mushrooms. There are many conventional techniques to protect the quality and increase the shelf life of mushrooms. Conventional procedures frequently result in considerable nutritional, texture, and flavor losses and shorter shelf lives. In contrast, modern technologies preserve mushrooms with increased nutritional retention, improved texture and flavor profiles, and longer shelf life. This review covers not only the conventional technologies like drying and cooling but also elaborates on the shelf‐life extension of mushrooms through novel technologies like pulse electric field, pulsed light, electrolyzed water, etc.
Loss of prohibitin 2 in Schwann cells dysregulates key transcription factors controlling developmental myelination
Authors: Wilson Emma R. , Nunes Gustavo Della‐Flora , Shen Shichen , Moore Seth , Gawron Joseph , Maxwell Jessica , Syed Umair , Hurley Edward , Lanka Meghana , Qu Jun , Désaubry Laurent , Wrabetz Lawrence , Poitelon Yannick , Feltri M. Laura 
Published: August 2024

AbstractSchwann cells are critical for the proper development and function of the peripheral nervous system (PNS), where they form a collaborative relationship with axons. Past studies highlighted that a pair of proteins called the prohibitins play major roles in Schwann cell biology. Prohibitins are ubiquitously expressed and versatile proteins. We have previously shown that while prohibitins play a crucial role in Schwann cell mitochondria for long‐term myelin maintenance and axon health, they may also be present at the Schwann cell‐axon interface during development. Here, we expand on this, showing that drug‐mediated modulation of prohibitins in vitro disrupts myelination and confirming that Schwann cell‐specific ablation of prohibitin 2 (Phb2) in vivo results in severe defects in radial sorting and myelination. We show in vivo that Phb2‐null Schwann cells cannot effectively proliferate and the transcription factors EGR2 (KROX20), POU3F1 (OCT6), and POU3F2 (BRN2), necessary for proper Schwann cell maturation, are dysregulated. Schwann cell‐specific deletion of Jun, a transcription factor associated with negative regulation of myelination, confers partial rescue of the developmental defect seen in mice lacking Schwann cell Phb2. Finally, we identify a pool of candidate PHB2 interactors that change their interaction with PHB2 depending on neuronal signals, and thus are potential mediators of PHB2‐associated developmental defects. This work develops our understanding of Schwann cell biology, revealing that Phb2 may modulate the timely expression of transcription factors necessary for proper PNS development, and proposing candidates that may play a role in PHB2‐mediated integration of axon signals in the Schwann cell.
Association between immune checkpoint inhibitor and cytomegalovirus infection: A pharmacovigilance study based on the adverse event reporting system
Authors: Okada Naoto , Yanagi Tomoyuki , Sasaki Takaaki , Tamura Miho , Ozaki Masakazu , Saisyo Atsuyuki , Kitahara Takashi 
Published: August 2024

AbstractImmune checkpoint inhibitor (ICI)‐induced adverse events due to excessive immune stimulation are problematic in immunotherapy. The activation of viral infection triggered by ICI‐induced dysregulated immunity has been proposed; however, this association remains inconsistent. This study investigated the association between ICI administration and cytomegalovirus (CMV) infections, a pathogen linked to immune abnormalities and reactivation, using the Food and Drug Administration Adverse Event Reporting System. We used the crude data set and immunocompromise‐free data set from the fourth quarter of 2012 to 2023. The disproportionality between CMV infection and ICI was analyzed using reporting odds ratio (ROR) and information component (IC) methodologies. Disproportionality between ipilimumab and nivolumab combination case and CMV infection was observed in the crude (ROR: 2.83, 95% confidence interval [CI]: 2.32–3.47; IC: 1.48, 95% CI: 1.14–1.73) and immunocompromise‐free data set (ROR: 1.76, 95% CI: 1.33–2.33; IC: 0.80, 95% CI: 0.33–1.14), whereas disproportionality between other ICI and CMV infection was not observed in the immunocompromise‐free data set. Multiple sensitivity analyses and time‐scan analysis also revealed the consistent disproportionality between ipilimumab and nivolumab combination cases and CMV infection, regardless of the host's immune status. While further research is warranted to validate our findings, these results highlight new insights into ICI‐induced viral infections and suggest the importance of considering the possibility of CMV infections during ipilimumab and nivolumab combination therapy, regardless of the host's immune status.
CircETV6 acts as an oncogenic driver in hepatocellular carcinoma progression
Authors: Li Xiaoqin , Jiang Xuemei , Lu Jing , Jiang Lan , Li Yan , Lin Yuting , Wan Feng , Wang Changmin 
Published: August 2024

AbstractCircular RNA (circRNA) plays important role in hepatocellular carcinoma (HCC) progression. However, the role and mechanism of circETV6 in HCC progression remain unclear. The levels of circETV6, ETV6, miR‐383‐5p, and PTPRE were tested by quantitative reverse‐transcription polymerase chain reaction. Cell functions were assessed using the 3‐(4,5‐dimethyl‐2‐thiazolyl)‐2,5‐diphenyl‐2H‐tetrazolium bromide assay, 5‐ethynyl‐2′‐deoxyuridine assay, colony formation assay, wound healing assay, transwell assay, and flow cytometry. The protein levels of poptosis‐related markers and PTPRE were determined by western blot analysis. RNA interaction was analyzed by dual‐luciferase reporter assay and RNA pull‐down assay. A xenograft model was established to assess circETV6 roles in vivo. CircETV6 was highly expressed in HCC tissues and cells. CircETV6 knockdown repressed HCC cell proliferation, migration, invasion, and cell cycle, while accelerated apoptosis. CircETV6 targeted miR‐383‐5p, and miR‐383‐5p inhibition reversed the regulation of circETV6 knockdown on HCC cell progression. CircETV6 promoted PTPRE level via targeting miR‐383‐5p. Overexpressed PTPRE abolished the inhibition effect of miR‐383‐5p on HCC cell progression. In addition, circETV6 knockdown slowed HCC tumor growth in vivo. CircETV6 might facilitate HCC progression via the miR‐383‐5p/PTPRE axis, providing a novel target for HCC treatment.
Incidence, description, and timing of serious and opportunistic infections in patients with hairy cell leukemia
Authors: Kapoor Nilesh , Zhao Qiuhong , Stiff Andrew , Bhat Seema A. , Anghelina Mirela I. , Andritsos Leslie A. , Blachly James S. , Epperla Narendranath , Boghdadly Zeinab El , Grever Michael R. , Rogers Kerry A. 
Published: August 2024

AbstractHairy cell leukemia is an uncommon B‐cell malignancy with excellent response to purine analogs and to targeted therapies such as ibrutinib and vemurafenib. However, purine analogs are known to be highly immunosuppressive and the infection burden in this patient population with current therapies is unknown. We therefore conducted a retrospective cohort study following 149 patients. Median follow‐up time was 6.9 years. Thirty‐six percent developed an opportunistic or serious infection requiring hospitalization. Most cases were bacterial and most coincided with neutropenia and/or CD4 T‐lymphopenia. No single treatment agent was significantly associated with increased or decreased incidence of infection. Reassuringly, the cumulative incidence of infections plateaued 2 months after initial treatment suggesting clinically significant immune recovery. Only one patient in our cohort passed away due to infection. Estimated 10‐year overall survival was 99% suggesting that infections may not cause as much mortality as was seen prior to current therapies.
Collaborative dynamics in open source software development: Unveiling the influence of team interaction and the role of project manager
Authors: Pal Sukrit , Nair Anand , Zuo Zhiya 
Published: August 2024

AbstractAs the world becomes increasingly reliant on open‐source software (OSS) development platforms, collaborative communication networks are becoming more complex, resulting in non‐trivial effects on project performance. This study examines the impact of communication network characteristics on project performance, measured in terms of the number of issues closed within OSS projects. Additionally, this research examines how this project outcome is affected by project managers' active participation in these communication networks. Using a panel dataset of 1599 projects spanning 104 weeks, with a total of 120,243 observations, we find that the density of communication network has an inverted U‐shaped relationship with project performance, that is, as the density of the communication network formed by team member interactions increases, project performance initially increases but then starts to decrease. Meanwhile, a project manager's participation in the communication network has no direct positive impact on project performance, but it flattens the inverted U‐shaped relationship, that is, it reduces the rate of decrease in project performance after the density of the communication network formed by project team members crosses the inflection point. These results provide valuable insights into the dynamics of communication networks in OSS projects and can help develop strategies for improving project performance.
Development of analytical method for determination of 1,3‐dimethylamylamine in sports nutrition and bodybuilding supplements using pH‐switchable deep eutectic solvents followed by high‐performance liquid chromatography‐diode array detector
Authors: Shen Dijun , Zhang Jie , Zhang Ying , Du Xiru 
Published: August 2024

In this work, an easy, safe, simple, and efficient pH‐switchable deep eutectic solvents (DESs)‐based liquid phase microextraction followed by high‐performance liquid chromatography‐diode array detector analysis was developed for the determination of 1,3‐dimethylamylamine (DMAA). The switchability of the obtained DESs was investigated by changing the pH. Then the best‐selected DES was characterized and the application of the selected DES in the extraction of DMAA from sports nutrition and bodybuilding supplements was investigated. The DES synthesized from l‐menthol: oleic acid in a molar ratio of 1:2 had the highest efficiency in the extraction of the target compound. Under the optimum conditions, (50 µL of DES, 100 µL of 4 mol/L KOH, 100 µL of 4 mol/L HCl, extraction time of 40 s and without salt addition) the calibration graph was linear in the range of 0.05–100 µg/kg and limit of detection was 0.02 µg/kg. The relative standard deviations including intra‐day and inter‐day for 10.0 µg/kg of DMAA in real samples were 2.7% (n = 7) and 5.3% (n = 7), respectively. The enrichment factor and percentage extraction recovery of the method were 283 and 85%, respectively. The relative recoveries for DMAA in different samples were in the range of 90%–109%.