bluuebunny/crossref_metadata_2025_split huggingface dataset:
Do video or telephone consultations impact attendance rates in an addiction medicine specialist outpatient clinic?
Authors: Hadinata Ignatius E. , Naren Thileepan , Rowland Bosco , Cook Jonathan , Nielsen Suzanne 
Published: June 2024

AbstractBackgroundEffective alcohol and other drugs (AODs) treatment has been proven to increase productivity and reduce costs to the community. Telehealth has previously been proven effective at delivering AOD treatment in the right settings. Yet, Australia's current Medicare funding restricts telephone consultations.AimWe hypothesise that treatment modality influences attendance rates. Specifically, telephone consultations can remove barriers to accessing treatment and, therefore, can increase attendance.MethodsWe conducted a retrospective audit on our addiction medicine specialist outpatient service from 1 July 2022 to 30 June 2023. A mixed‐effects logistic regression model was used to analyse factors associated with attendance rates.ResultsThere were 576 participants in the study, and 3354 appointments were booked over the 12‐month study period. Of these, 2695 were face‐to‐face, 541 were telephone and 118 were video. The unadjusted raw attendance rate was highest in the telephone group (87.24%), followed by face‐to‐face (73.02%) and video (44.92%). After adjusting for covariates, telephone consultation was associated with significantly increased odds of attending compared to face‐to‐face (odds ratio (OR) = 2.60, 95% confidence interval (CI) = 1.90–3.54, P < 0.001). Video consultation was associated with a 69% reduction in the odds of attending compared to face‐to‐face (OR = 0.31, 95% CI = 0.019–0.49, P < 0.001).ConclusionsWhile physical attendance may be required for specific clinical care, telephone consultations are associated with increased attendance and can form an important adjunct to delivering addiction treatment. Given the substantial costs of substance use disorders, this could inform government policies and funding priorities to further improve access and treatment outcomes.
Enhanced mechanical and wave‐absorption properties of SiC–Si3N4–FeSi porous ceramics by introducing Al
Authors: Zhang Huihui , Ma Guocheng , Wu Haibo , Yuan Ming , Liu Xuejian , Huang Zhengren 
Published: June 2024

AbstractSiC‐based porous ceramic wave‐absorbing materials have attracted much attention due to their excellent properties such as low density, high‐temperature resistance, and oxidation resistance. In this work, the impedance matching of SiC ceramics is improved by introducing Si3N4 wave‐transparent phase, and the dielectric loss capability of SiC ceramics is enhanced by introducing FeSi wave loss phase. To achieve a balance between impedance matching and absorption loss in porous ceramics, different molar contents of Al were introduced into FeSi to tailor electromagnetic parameters. The effects of introducing FeAlxSi1−x on the phase composition, microstructure, dielectric loss, and microwave absorption mechanism of SiC–Si3N4 porous ceramics were systematically investigated. When FeAl0.25Si0.75 is added, the minimum reflection loss of the porous ceramics is as low as −58.02 dB, and the flexural strength is as high as 87.23 MPa. The presence of Al promotes the transformation of the Si3N4 crystal and the generation of Al2O3. The introduction of FeAl0.25Si0.75 into SiC–Si3N4 has constructed “inductor–capacitor–resistance” microcircuit, which enhances polarization loss, conductivity loss, and magnetic loss, and realized the double enhancement of the mechanical and wave‐absorbing properties of porous ceramics.
Are women penalized for showing pride at work? Gender disparities in the competence‐warmth tradeoff
Authors: Burke Vanessa , Grandey Alicia A. , Melloy Robert C. , Ferris D. Lance , England Katelyn 
Published: June 2024

AbstractShowing pride at work clearly communicates personal success (i.e., high competence) and boosts status; yet some evidence suggests it can also signal self‐focus and insensitivity to others (i.e., low warmth). Prior scholars have proposed gender differences explain mixed findings, but with limited support. We propose that the benefit‐cost tradeoff depends on the displayer's gender in conjunction with the social context of the display. We test the contextualized dual‐signaling model of employee pride displays, uniquely assessing how the signaler's gender and receiver's social motives (between‐person comparisons) change first‐impressions of competence and warmth after one or repeated exposures (i.e., within‐person comparisons). Study 1 was a 2 (signaler gender) by 2 (signal context) design obtaining judgments before and after seeing a dynamic pride display. Pride displays increased competence similarly across employee gender, but women saw significantly greater costs to warmth when displays were public (i.e., coworkers present), a violation of gender norms. In Study 2, we replicate this finding regardless of whether coworkers were collaborators or competitors (between‐person), and found repeated displays increase the warmth cost for women and the competence gains for men. In Study 3, we compare the costs for women of confirming gender norms for warmth (i.e., happiness display) or violating gender norms for warmth but conforming to leader norms for competence (i.e., pride display). Results suggest “happy” women are preferred as leaders over “proud” women despite higher competence. We clarify mixed findings and confirm the need for contextualized theory to understand gender differences in pride displays and career trajectories.
Relationship between circulating thrombospondin‐1 messenger ribonucleic acid and microribonucleic acid‐194 levels in Chinese patients with type 2 diabetic kidney disease: The outcomes of a case–control study
Authors: Ma Ning , Liu Weiwei , Xu Ning , Yin Dong , Zheng Ping , Wang Guofeng , Hui Yuan , Zhang Jiping , Han Guanjun , Yang Chuanhui , Lu Yan , Cheng Xingbo 
Published: June 2024

AbstractAims/IntroductionWe investigated the relationship of circulating TSP‐1 mRNA and miR‐194 with diabetic kidney disease’s degree.Materials and MethodsWe enrolled 167 hospitalized type 2 diabetes patients in the endocrinology department. Patients were split into three groups according to urinary microalbumin: A, B and C. The control group comprised healthy outpatients (n = 163). The quantities of microribonucleic acid (miR)‐194 and thrombospondin‐1 (TSP‐1) messenger ribonucleic acid (mRNA) in the participants’ circulation were measured using a quantitative real‐time polymerase chain reaction.ResultsCirculating TSP‐1 mRNA (P = 0.024) and miR‐194 (P = 0.029) expressions significantly increased in type 2 diabetes patients. Circulating TSP‐1 mRNA (P = 0.040) and miR‐194 (P = 0.007) expression levels differed significantly among the three groups; circulating TSP‐1 mRNA expression increased with urinary microalbumin. However, miR‐194 declined in group B and increased in group C. Circulating TSP‐1 mRNA was positively correlated with cystatin‐c (r = 0.281; P = 0.021) and microalbumin/creatinine ratio (UmALB/Cr; r = 0.317; P = 0.009); miR‐194 was positively correlated with UmALB/Cr (r = 0.405; P = 0.003). Stepwise multivariate linear regression analysis showed cystatin‐c (β = 0.578; P = 0.021) and UmALB/Cr (β = 0.001; P = 0.009) as independent factors for TSP‐1 mRNA; UmALB/Cr (β = 0.005; P = 0.028) as an independent factor for miR194. Areas under the curve for circulating TSP‐1 mRNA and miR194 were 0.756 (95% confidence interval 0.620–0.893; sensitivity 0.69 and specificity 0.71, P < 0.01) and 0.584 (95% confidence interval 0.421–0.748; sensitivity 0.54 and specificity 0.52, P < 0.01), respectively.ConclusionsCirculating TSP‐1 mRNA and miR‐194 expressions significantly increased in type 2 diabetes patients. The microalbumin group had lower levels of miR‐194 (a risk factor that is valuable for type 2 diabetes kidney disease evaluation).
How to overcome constraints imposed by microsporidian genome features to ensure gene prediction?
Authors: Peyretaillade Eric , Akossi Reginal F. , Tournayre Jérémy , Delbac Frédéric , Wawrzyniak Ivan 
Published: June 2024

AbstractSince the advent of sequencing techniques and due to their continuous evolution, it has become easier and less expensive to obtain the complete genome sequence of any organism. Nevertheless, to elucidate all biological processes governing organism development, quality annotation is essential. In genome annotation, predicting gene structure is one of the most important and captivating challenges for computational biology. This aspect of annotation requires continual optimization, particularly for genomes as unusual as those of microsporidia. Indeed, this group of fungal‐related parasites exhibits specific features (highly reduced gene sizes, sequences with high rate of evolution) linked to their evolution as intracellular parasites, requiring the implementation of specific annotation approaches to consider all these features. This review aimed to outline these characteristics and to assess the increasingly efficient approaches and tools that have enhanced the accuracy of gene prediction for microsporidia, both in terms of sensitivity and specificity. Subsequently, a final part will be dedicated to postgenomic approaches aimed at reinforcing the annotation data generated by prediction software. These approaches include the characterization of other understudied genes, such as those encoding regulatory noncoding RNAs or very small proteins, which also play crucial roles in the life cycle of these microorganisms.
Informal caregiver and healthcare professional perspectives on dementia and nutrition
Authors: Labyak Corinne , Sealey‐Potts Claudia , Wright Lauri , Kriek Crystal , Dilts Stephenie 
Published: June 2024

AbstractBackgroundPersons living with dementia and informal caregivers are at a higher risk for malnutrition. Most caregivers are not experts at identifying nutritional complications of dementia. Therefore, we aimed to identify nutrition knowledge and challenges related to feeding and caring for persons with dementia to develop a meaningful intervention.MethodsA mixed‐methods approach was used. Eight focus groups were conducted with caregivers of persons living with dementia (n = 28) and healthcare professionals (n = 23). Data was analysed using NVivo software. A questionnaire was administered to identify nutritional challenges. A modified food frequency questionnaire assessed food patterns of caregivers and persons with dementia. Results were compared to Mediterranean‐DASH Intervention for Neurodegenerative Delay (MIND) dietary guidelines. Data were analysed using SPSS software.ResultsFour major themes emerged: forgetting to eat, developing food aversions, strong preferences for sweets and weight changes. Findings revealed common strategies used to improve nutrition intake included cueing, supplements and quiet eating environment. Caregivers were impacted by stress leading to poorer food choices and exhaustion. Recommendations for a caregiver program made by participants included education, resources and support. Findings from the food frequencies questionnaire survey showed most participants had a lower dietary diversity compared to the MIND diet guidelines.ConclusionsWith both groups being more prone to malnutrition, this research shows that participants were less likely to obtain adequate nutrition for brain health. Additionally, caregivers are dealing with nutrition issues themselves and their person living with dementia. The findings support the need for registered dietitians to provide tailored nutrition interventions for these families.
Using a nonparametric item response theory model to identify patterns of cognitive decline: The Mokken scale analysis
Authors: Calderón Carlos , Palominos Diego , Véliz‐García Óscar , Ramos‐Henderson Miguel , Bekios‐Canales Nikolás , Beyle Christian , Ávalos‐Tejeda Marcelo , Domic‐Siede Marcos 
Published: June 2024

AbstractCognitive decline, particularly in dementia, presents complex challenges in early detection and diagnosis. While Item Response Theory (IRT) has been instrumental in identifying patterns of cognitive impairment through psychometric tests, its parametric models often require large sample sizes and strict assumptions. This creates a need for more adaptable, less demanding analytical methods. This study aimed to evaluate the effectiveness of Mokken scale analysis (MSA), a nonparametric IRT model, in identifying hierarchical patterns of cognitive impairment from psychometric tests. Using data from 1164 adults over 60 years old, we applied MSA to the orientation subscale of ACE‐III. Our analysis involved calculating scalability, monotone homogeneity, invariant item ordering (IIO) and response functions. The MSA effectively retrieved the hierarchical order of cognitive impairment patterns. Most items showed strong scalability and consistent patterns of cognitive performance. However, challenges with IIO were observed, particularly with items having adjacent difficulty parameters. The findings highlight MSA's potential as a practical alternative to parametric IRT models in cognitive impairment research. Its ability to provide valuable insights into patterns of cognitive deterioration, coupled with less stringent requirements, makes it a useful tool for clinicians and researchers.
Trends in and factors associated with family physician‐performed screening colonoscopies in the United States: 2016‐2021
Authors: Edwardson Nicholas , van der Goes David , Pankratz V. Shane , Parasher Gulshan , Adsul Prajakta , English Kevin , Sheche Judith , Mishra Shiraz I. 
Published: June 2024

AbstractPurposeFamily physician (FP)‐performed screening colonoscopies can serve as 1 strategy in the multifaceted strategy necessary to improve national colorectal cancer screening rates, particularly in rural areas where specialist models can fail. However, little research exists on the performance of this strategy in the real world. In this study, we evaluated trends in and factors associated with FP‐performed screening colonoscopies in the United States between 2016 and 2021.MethodsUsing national data from Merative's Marketscan insurance claims database, we estimate the proportion of screening colonoscopies performed by FPs. We use logistic regression models to evaluate factors independently associated with FP‐performed colonoscopies.ResultsThe percentage of screening colonoscopies performed by FPs exhibited a downward trend from 11.32% in 2016 to 6.73% in 2021, with the largest decrease occurring among patients from the most rural areas. FPs were more likely to perform colonoscopies on slightly older patients, male patients, and rural patients. Patients were less likely to receive FP‐performed colonoscopies in large metropolitan areas compared to lesser populated areas. Patients were more likely to receive FP‐performed colonoscopies in the Midwest, South, and West, even after accounting for urban‐rural classification.ConclusionDespite a downward trajectory, FPs perform a substantial proportion of screening colonoscopies in the United States. Changes to the business side of health care delivery may be contributing to the observed decreasing rate. Whether through spatial or relational proximity, FPs may be better positioned to provide colonoscopy to some rural, male, and older patients who otherwise may not have been screened. Policy changes to expand the FP workforce, particularly in rural areas, are likely necessary to slow or reverse the downward trend of FP‐performed screening colonoscopies.
The reactivity of experimentally reduced lunar regolith simulants: Health implications for future crewed missions to the lunar surface
Authors: Hendrix Donald A. , Catalano Tristan , Nekvasil Hanna , Glotch Timothy D. , Legett Carey , Hurowitz Joel A. 
Published: June 2024

AbstractCrewed missions to the Moon may resume as early as 2026 with NASA's Artemis III mission, and lunar dust exposure/inhalation is a potentially serious health hazard that requires detailed study. Current dust exposure limits are based on Apollo‐era samples that spent decades in long‐term storage on Earth; their diminished reactivity may lead to underestimation of potential harm that could be caused by lunar dust exposure. In particular, lunar dust contains nanophase metallic iron grains, produced by “space weathering”; the reactivity of this unique component of lunar dust is not well understood. Herein, we employ a chemical reduction technique that exposes lunar simulants to heat and hydrogen gas to produce metallic iron particles on grain surfaces. We assess the capacity of these reduced lunar simulants to generate hydroxyl radical (OH*) when immersed in deionized (DI) water, simulated lung fluid (SLF), and artificial lysosomal fluid (ALF). Lunar simulant reduction produces surface‐adhered metallic iron “blebs” that resemble nanophase metallic iron particles found in lunar dust grains. Reduced samples generate ~5–100× greater concentrations of the oxidative OH* in DI water versus non‐reduced simulants, which we attribute to metallic iron. SLF and ALF appear to reduce measured OH*. The increase in observed OH* generation for reduced simulants implies high oxidative damage upon exposure to lunar dust. Low levels of OH* measured in SLF and ALF imply potential damage to proteins or quenching of OH* generation, respectively. Reduction of lunar dust simulants provides a quick cost‐effective approach to study dusty materials analogous to authentic lunar dust.
N‐terminal acetylation orchestrates glycolate‐mediated ROS homeostasis to promote rice thermoresponsive growth
Authors: Li Xueting , Tang Huashan , Xu Ting , Wang Pengfei , Ma Fangfang , Wei Haifang , Fang Zi , Wu Xiaoyan , Wang Yanan , Xue Yongbiao , Zhang Biyao 
Published: June 2024

Summary

Climate warming poses a significant threat to global crop production and food security. However, our understanding of the molecular mechanisms governing thermoresponsive development in crops remains limited.

Here we report that the auxiliary subunit of N‐terminal acetyltransferase A (NatA) in rice OsNAA15 is a prerequisite for rice thermoresponsive growth. OsNAA15 produces two isoforms OsNAA15.1 and OsNAA15.2, via temperature‐dependent alternative splicing. Among the two, OsNAA15.1 is more likely to form a stable and functional NatA complex with the potential catalytic subunit OsNAA10, leading to a thermoresponsive N‐terminal acetylome. Intriguingly, while OsNAA15.1 promotes plant growth under elevated temperatures, OsNAA15.2 exhibits an inhibitory effect.

We identified two glycolate oxidases (GLO1/5) as major substrates from the thermoresponsive acetylome. These enzymes are involved in hydrogen peroxide (H2O2) biosynthesis via glycolate oxidation. N‐terminally acetylated GLO1/5 undergo their degradation through the ubiquitin‐proteasome system. This leads to reduced reactive oxygen species (ROS) production, thereby promoting plant growth, particularly under high ambient temperatures.

Conclusively, our findings highlight the pivotal role of N‐terminal acetylation in orchestrating the glycolate‐mediated ROS homeostasis to facilitate thermoresponsive growth in rice.
Etiology of injustice: An introduction
Authors: Erck Susan 
Published: June 2024

AbstractTo formulate a plan of action for bringing about a decisive and reasonably stable end to an injustice, it is helpful to understand the factors and conditions that critically make the difference in causing that injustice. This intuitively seems correct regarding active and ongoing problems. But what precisely is involved in this kind of explanatory endeavor, and what is its role in practical efforts to confront existing wrongs? This paper offers an introduction to etiology of injustice, which is the study and explanation of the operative causation of injustices. Drawing on insights from the philosophy of social transformation, causation, and remedial justice, I sketch a conceptual framework for understanding and undertaking the task of etiology of injustice and outline the contours of the etiological tradition of thought.
The mitigating effect of street trees, urban flora, and the suburban environment on seasonal peak UV indices: A case study from Brisbane, Australia
Authors: Downs Nathan James , Amar Abdurazaq , Dearnaley John , Butler Harry , Dekeyser Stijn , Igoe Damien , Parisi Alfio V. , Raj Nawin , Deo Ravinesh , Turner Joanna 
Published: June 2024

AbstractTree shade, particularly shade that obscures direct sunlight near peak periods of midday solar exposure can have a pronounced effect on potentially harmful ultraviolet radiation, and in turn, strongly influence the maximum daily UV index (UVI). In this study, the seasonal influence of tree shade on the UVI is evaluated from 210 hemispherical sky view images collected alongside public walkways and footpaths from 10 residential Brisbane suburbs. The effective sidewalk UV index is calculated underneath planted tree canopies, adjacent residential gardens, buildings and background tree species. Results are presented with respect to seasonal variations in the diurnal solar elevation for each month of the year at Brisbane's latitude. The research also examines the total reduction in UVI due to the presence of individual tree species, showing reductions in the midday UVI of up to 91% of an equivalent unimpeded sky hemisphere when overhead tree canopies are present. Important footpath tree species for peak midday UVI mitigation include Pongamia pinnata, Xanthostemon chrysanthus, Senna siamea, and Libidibia ferrea. The planting and maintenance of existing tree species already growing alongside residential Brisbane streets will improve the shade characteristics of suburbs and enhance UV protection for local residents.
Why are the inner and outer sides of many flower petals differently coloured?
Authors: Fan X.‐Q. , Trunschke J. , Ren Z.‐X. , Wang H. , Pyke G. H. , van der Kooi C. J. , Lunau K. 
Published: June 2024

AbstractThe flower perianth has various, non‐mutually exclusive functions, such as visual signalling to pollinators and protecting the reproductive organs from the elements and from florivores, but how different perianth structures and their different sides play a role in these functions is unclear. Intriguingly, in many species there is a clear colour difference between the different sides of the perianth, with colour patterns or pigmentation present on only one side. Any adaptive benefit from such colour asymmetry is unclear, as is how the asymmetry evolved. In this viewpoint paper, we address the phenomenon of flowers with differently coloured inner and outer perianth sides, focusing on petals of erect flowers. Guided by existing literature and our own observations, we delineate three non‐mutually exclusive evolutionary hypotheses that may explain the factors underlying differently coloured perianth sides. The pollen‐protection hypothesis predicts that the outer side of petals contributes to protect pollen against UV radiation, especially during the bud stage. The herbivore‐avoidance hypothesis predicts that the outer side of petals reduces the flower's visibility to herbivores. The signalling‐to‐pollinators hypothesis predicts that flower colours evolve to increase conspicuousness to pollinators. The pollen‐protection hypothesis, the herbivore‐avoidance hypothesis, and the signalling‐to‐pollinators hypothesis generate largely but not entirely overlapping predictions about the colour of the inner and outer side of the petals. Field and laboratory research is necessary to disentangle the main drivers and adaptive significance of inner–outer petal side colour asymmetry.