bluuebunny/crossref_metadata_2025_split huggingface dataset:
SOWING WINDOWS FOR A SPRING CROP INTRODUCED IN RICE CULTIVATION AREAS AFFECTED BY LOW TEMPERATURE AND RADIATION
Authors: QUYEN LUU NGOC , AFFHOLDER FRANÇOIS , MONTAGNE JENNIFER , JOURDAIN DAMIEN , RIPOCHE AUDE , CAPILLON ALAIN 
Published: January 2015

SUMMARYIn mountainous areas of Continental South East Asia, double cropping in the irrigable valleys and terraces is often promoted as a way to increase farmers’ income while alleviating the pressure of agriculture on fragile slopes. However, cold temperature and low global radiation may constrain this strategy. Lethally cold events may occur, and increases in crop cycle length may jeopardize the correct timing of the main rice crop, taking place in summer. The model PYE (potential yield estimator) simulating the impact of temperature and radiation on the development and yield of annual crops was adapted to account for the range of temperature occurring in the area under study. It was calibrated against experimental data for the three crops that are most often considered as spring crops in the irrigable land of the northern mountains of Vietnam: rice, soybean and maize. Then a virtual experiment was designed in order to simulate various scenarios combining crop species and sowing date with climatic data accounting for variability of climate across years, location and elevation. Completed with a sensitivity analysis, it allowed to define favourable ‘sowing windows’ for non-water limited environments, based on the three following criteria: high average yield, low incidence over years of lethally cold events and low incidence over years of delays in the maturity of the spring crop. The length of this sowing window varied greatly across the scenarios tested. The widest was obtained for the case of soybean whatever the location and elevation, which makes it the less risky of the tested options. The approach followed proved effective to identify favourable and unfavourable environments in order to help better targeting the policy in support to the introduction of a spring crop in the mountains of Vietnam.
ECOPHYSIOLOGICAL TRAITS OF ADULT TREES OF CRIOLLO COCOA CULTIVARS (THEOBROMA CACAOL.) FROM A GERMPLASM BANK IN VENEZUELA
Authors: ÁVILA-LOVERA ELEINIS , CORONEL ILSA , JAIMEZ RAMÓN , URICH ROSA , PEREYRA GABRIELA , ARAQUE OSMARY , CHACÓN IRAIMA , TEZARA WILMER 
Published: January 2015

SUMMARYWe studied physiological traits of 12 Criollo cocoa cultivars growing in a germplasm bank in the southern region of Maracaibo Lake Basin, during the rainy (RS) and dry seasons (DS) of 2007. A further evaluation of photosynthetic responses to changes in environmental parameters was done on three cultivars: Los Caños 001 (LCA001), Sur Porcelana 010 (SP010) and Escalante 001 (ESC001) in 2009 and 2010. Leaf water potential (ΨL) of most cultivars decreased during the DS of 2007, with the exception of ESC001. Maximum photosynthetic rate (Amax), stomatal conductance and water use efficiency varied among cultivars and seasons. The CO2-saturated photosynthetic rate (ACO2sat) was higher in LCA001 and ESC001 than in SP010, with no differences in carboxylation efficiency. Light curve responses of the three cultivars were similar. In all cultivars, no evidence of chronic photoinhibition was observed, since maximum quantum yield of photosystem II was high (0.77–0.81). We conclude that ESC001 has the best physiological performance (ΨLremained unchanged, highest Amax, ACO2satand photochemical activity), and it seems to be a promising cultivar for cocoa agroforestry systems in the southern region of Maracaibo.
CONSANGUINITY AND HOMOZYGOSITY AMONG TUNISIAN PATIENTS WITH AN AUTOSOMAL RECESSIVE DISORDER
Authors: KELMEMI WIDED , CHELLY IMENE , KHARRAT MAHER , CHAABOUNI-BOUHAMED HABIBA 
Published: January 2015

SummaryConsanguineous unions are a deeply rooted social practice among traditional societies. Despite their presumed social advantages, they can result in several health conditions. The aim of this study was: i) to compare consanguinity levels between Tunisian patients affected with autosomal recessive disorders (ARDs) and those with a chromosomal abnormality; and ii) to gain more insight into the mutational status of patients affected with ARDs. Data were collected from 290 files of patients affected by one of five ARDs confirmed by molecular analysis and 248 files of patients with confirmed Down syndrome. Information on the disease, mutation defining the disease, parents' relatedness and geographical origin was gathered. Consanguinity was found among 58% of the ARD patients and among 22% of Down syndrome patients, and a homozygous status was found in 90% of the patients born to related parents and in 70% of patients born to unrelated parents. Also, children from unrelated parents from the same geographical background were found to be more frequently affected by homozygous mutations than those from unrelated parents from different geographical backgrounds. The present study shows how marriage practices affect patterns of genetic variations and how they can lead to homogenization in the genetic pool.
A remarkable newRamonia(Gyalectaceae) from Brazil, with a key to the species
Authors: APTROOT André , SOBREIRA Priscylla Nayara Bezerra , CÁCERES Marcela Eugenia da Silva 
Published: January 2015

AbstractA new corticolous lichen speciesRamonia variosporais described from Brazil. It has a verrucose thallus, concave, initally almost closed apothecia and variably 8 orc.32–64, 1-septate ascospores per ascus; when 8 per ascus, ellipsoid and 16–22×6–10 µm; whenc.32–64 per ascus, broadly ellipsoid and 10–14×6–8 µm. A revised world key is given to all currently known species ofRamonia.
A new species ofAllocetraria(Parmeliaceae, Ascomycota) in China
Authors: WANG Rui-Fang , WEI Xin-Li , WEI Jiang-Chun 
Published: January 2015

AbstractAllocetraria yunnanensisR. F. Wang, X. L. Wei & J. C. Wei is described as a new species from the Yunnan Province of China, and is characterized by having a shiny upper surface, strongly wrinkled lower surface, and marginal pseudocyphellae present on the lower side in the form of a white continuous line or spot. The phylogenetic analysis based on nrDNA ITS sequences suggests that the new species is related toA. sinensisX. Q. Gao.
Three new lichen species from Nicaragua, with keys to the known species of Eugeniella and Malmidea
Authors: BREUSS Othmar , LÜCKING Robert 
Published: January 2015

AbstractEugeniella palleola, Graphis paraschiffneri, and Malmidea cineracea are described from Nicaragua. Eugeniella palleola is characterized by having pale apothecial discs and prominent, white margins, and producing a complex chemistry including atranorin, stictic and norstictic acids, and an unknown substance. Graphis paraschiffneri has lirellae with a lateral thalline margin, striate labia, a completely carbonized excipulum, transversely septate ascospores, and contains norstictic acid in the thallus. Malmidea cineracea is characterized by a granulose-isidiate thallus with a yellowish medulla and a compact, crystal-encrusted excipulum. Malmidea nigromarginata and M. piperina are proposed as new combinations. Keys are presented to all known species of Eugeniella (9) and Malmidea (50).
FFQ for the adult population of the capital of Ecuador (FFQ-Quito): development, reliability and validity
Authors: Silva-Jaramillo Katherine M , Neutzling Marilda B , Drehmer Michele 
Published: January 2015

AbstractObjectiveTo assess the reliability and validity of a semi-quantitative FFQ designed to evaluate the usual nutrient intake of adults in Quito, Ecuador.DesignDietary data using 24 h recalls (24hR) were used to design a list of commonly consumed foods. The relative validity of a 111-item FFQ was evaluated by comparing nutrient intakes against three non-consecutive 24hR. All nutrients were energy-adjusted. Reliability was assessed using two FFQ (FFQ1 and FFQ2) and assessed by the intra-class correlation coefficient. The comparisons between the FFQ and the 24hR were assessed by the de-attenuated Pearson correlation coefficient, weighted kappa and by Bland–Altman plots.SettingQuito, Ecuador.SubjectsOverall, 345 adults were enrolled in the present study. Two hundred and fifty participated in FFQ development and ninety-five participated in the FFQ validity and reliability.ResultsThe FFQ produced higher energy and nutrient intakes. Reliability correlation coefficients after adjusting for energy ranged from 0·62 to 0·88 for protein and Ca, respectively. For the validity study, energy-adjusted and de-attenuated correlation coefficients between the questionnaire and the 24hR ranged from 0·21 for fat to 0·65 for Ca. Only 4 % of the participants were grossly misclassified and 46 % had weighted kappa higher than 0·42. The Bland–Altman plot showed a constant bias with a tendency to increase according to the intake level.ConclusionsThe FFQ showed reasonably good relative validity and reliable measurements, especially for nutrients considered protective and risk markers of non-communicable disease, and can be used to assess usual nutrient intake in this population.
DRAM1 regulates apoptosis through increasing protein levels and lysosomal localization of BAX
Authors: Guan J-J , Zhang X-D , Sun W , Qi L , Wu J-C , Qin Z-H 
Published: January 2015

AbstractDRAM1 (DNA damage-regulated autophagy modulator 1) is a TP53 target gene that modulates autophagy and apoptosis. We previously found that DRAM1 increased autophagy flux by promoting lysosomal acidification and protease activation. However, the molecular mechanisms by which DRAM1 regulates apoptosis are not clearly defined. Here we report a novel pathway by which DRAM1 regulates apoptosis involving BAX and lysosomes. A549 or HeLa cells were treated with the mitochondrial complex II inhibitor, 3-nitropropionic acid (3NP), or an anticancer drug, doxorubicin. Changes in the protein and mRNA levels of BAX and DRAM1 and the role of DRAM1 in BAX induction were determined. The interaction between DRAM1 and BAX and its effect on BAX degradation, BAX lysosomal localization, the release of cathepsin B and cytochrome c by BAX and the role of BAX in 3NP- or doxorubicin-induced cell death were studied. The results showed that BAX, a proapoptotic protein, was induced by DRAM1 in a transcription-independent manner. BAX was degraded by autophagy under basal conditions; however, its degradation was inhibited when DRAM1 expression was induced. There was a protein interaction between DRAM1 and BAX and this interaction prolonged the half-life of BAX. Furthermore, upregulated DRAM1 recruited BAX to lysosomes, leading to the release of lysosomal cathepsin B and cleavage of BID (BH3-interacting domain death agonist). BAX mediated the release of mitochondrial cytochrome c, activation of caspase-3 and cell death partially through the lysosome-cathepsin B-tBid pathway. These results indicate that DRAM1 regulates apoptosis by inhibiting BAX degradation. In addition to mitochondria, lysosomes may also be involved in BAX-initiated apoptosis.
miR-34a regulates cell proliferation, morphology and function of newborn neurons resulting in improved behavioural outcomes
Authors: Mollinari C , Racaniello M , Berry A , Pieri M , de Stefano M C , Cardinale A , Zona C , Cirulli F , Garaci E , Merlo D 
Published: January 2015

AbstractmiR-34a is involved in the regulation of the fate of different cell types. However, the mechanism by which it controls the differentiation programme of neural cells remains largely unknown. Here, we investigated the role of miR-34a in neurogenesis and maturation of developing neurons and identified Doublecortin as a new miR-34a target. We found that the overexpression of miR-34a in vitro significantly increases precursor proliferation and influences morphology and function of developing neurons. Indeed, miR-34a overexpressing neurons showed a decreased expression of several synaptic proteins and receptor subunits, a decrement of NMDA-evoked current density and, interestingly, a more efficient response to synaptic stimulus. In vivo, miR-34a overexpression showed stage-specific effects. In neural progenitors, miR-34a overexpression promoted cell proliferation, in migratory neuroblasts reduced the migration and in differentiating newborn neurons modulated process outgrowth and complexity. Importantly, we found that rats overexpressing miR-34a in the brain have better learning abilities and reduced emotionality.
Targeting MKK3 as a novel anticancer strategy: molecular mechanisms and therapeutical implications
Authors: Baldari S , Ubertini V , Garufi A , D'Orazi G , Bossi G 
Published: January 2015

AbstractMitogen-activated protein kinase kinase 3 (MAP2K3, MKK3) is a member of the dual specificity protein kinase group that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic or stress-inducing stimuli and participates in the MAP kinase-mediated signaling cascade, leading to cell proliferation and survival. Several studies highlighted a critical role for MKK3 in tumor progression and invasion, and we previously identified MKK3 as transcriptional target of mutant (mut) p53 to sustain cell proliferation and survival, thus rendering MKK3 a promising target for anticancer therapies. Here, we found that targeting MKK3 with RNA interference, in both wild-type (wt) and mutp53-carrying cells, induced endoplasmic reticulum stress and autophagy that, respectively, contributed to stabilize wtp53 and degrade mutp53. MKK3 depletion reduced cancer cell proliferation and viability, whereas no significant effects were observed in normal cellular context. Noteworthy, MKK3 depletion in combination with chemotherapeutic agents increased tumor cell response to the drugs, in both wtp53 and mutp53 cancer cells, as demonstrated by enhanced poly (ADP-ribose) polymerase cleavage and reduced clonogenic ability in vitro. In addition, MKK3 depletion reduced tumor growth and improved biological response to chemotherapeutic in vivo. The overall results indicate MKK3 as a novel promising molecular target for the development of more efficient anticancer treatments in both wtp53- and mutp53-carrying tumors.
Generalization of word meanings during infant sleep
Authors: Friedrich Manuela , Wilhelm Ines , Born Jan , Friederici Angela D. 
Published: January 2015

AbstractSleep consolidates memory and promotes generalization in adults, but it is still unknown to what extent the rapidly growing infant memory benefits from sleep. Here we show that during sleep the infant brain reorganizes recent memories and creates semantic knowledge from individual episodic experiences. Infants aged between 9 and 16 months were given the opportunity to encode both objects as specific word meanings and categories as general word meanings. Event-related potentials indicate that, initially, infants acquire only the specific but not the general word meanings. About 1.5 h later, infants who napped during the retention period, but not infants who stayed awake, remember the specific word meanings and, moreover, successfully generalize words to novel category exemplars. Independently of age, the semantic generalization effect is correlated with sleep spindle activity during the nap, suggesting that sleep spindles are involved in infant sleep-dependent brain plasticity.
Benefits of rice seed priming are offset permanently by prolonged storage and the storage conditions
Authors: Hussain Saddam , Zheng Manman , Khan Fahad , Khaliq Abdul , Fahad Shah , Peng Shaobing , Huang Jianliang , Cui Kehui , Nie Lixiao 
Published: January 2015

AbstractSeed priming is a commercially successful practice, but reduced longevity of primed seeds during storage may limit its application. We established a series of experiments on rice to test: (1) whether prolonged storage of primed and non-primed rice seeds for 210 days at 25°C or −4°C would alter their viability, (2) how long primed rice seed would potentially remain viable at 25°C storage and (3) whether or not post-storage treatments (re-priming or heating) would reinstate the viability of stored primed seeds. Two different rice cultivars and three priming agents were used in all experiments. Prolonged storage of primed seeds at 25°C significantly reduced the germination (>90%) and growth attributes (>80%) of rice compared with un-stored primed seeds. However, such negative effects were not observed in primed seeds stored at −4°C. Beneficial effects of seed priming were maintained only for 15 days of storage at 25°C, beyond which the performance of primed seeds was worse even than non-primed seeds. The deteriorative effects of 25°C storage were related with hampered starch metabolism in primed rice seeds. None of the post-storage treatments could reinstate the lost viability of primed seeds suggesting that seeds become unviable by prolonged post-priming storage at 25°C.
Fully printed flexible and disposable wireless cyclic voltammetry tag
Authors: Jung Younsu , Park Hyejin , Park Jin-Ah , Noh Jinsoo , Choi Yunchang , Jung Minhoon , Jung Kyunghwan , Pyo Myungho , Chen Kevin , Javey Ali , Cho Gyoujin 
Published: January 2015

AbstractA disposable cyclic voltammetry (CV) tag is printed on a plastic film by integrating wireless power transmitter, polarized triangle wave generator, electrochemical cell and signage through a scalable gravure printing method. By proximity of 13.56 MHz RF reader, the printed CV tag generates 320 mHz of triangular sweep wave from +500 mV to −500 mV which enable to scan a printed electrochemical cell in the CV tag. By simply dropping any specimen solution on the electrochemical cell in the CV tag, the presence of solutes in the solution can be detected and shown on the signage of the CV tag in five sec. 10 mM of N,N,N′,N′-tetramethyl-p-phenylenediamine (TMPD) was used as a standard solute to prove the working concept of fully printed disposable wireless CV tag. Within five seconds, we can wirelessly diagnose the presence of TMPD in the solution using the CV tag in the proximity of the 13.56 MHz RF reader. This fully printed and wirelessly operated flexible CV tag is the first of its kind and marks the path for the utilization of inexpensive and disposable wireless electrochemical sensor systems for initial diagnose hazardous chemicals and biological molecules to improve public hygiene and health.
Three-Dimensional Optical Trapping of a Plasmonic Nanoparticle using Low Numerical Aperture Optical Tweezers
Authors: Brzobohatý Oto , Šiler Martin , Trojek Jan , Chvátal Lukáš , Karásek Vítězslav , Paták Aleš , Pokorná Zuzana , Mika Filip , Zemánek Pavel 
Published: January 2015

AbstractIt was previously believed that larger metal nanoparticles behave as tiny mirrors that are pushed by the light beam radiative force along the direction of beam propagation, without a chance to be confined. However, several groups have recently reported successful optical trapping of gold and silver particles as large as 250 nm. We offer a possible explanation based on the fact that metal nanoparticles naturally occur in various non-spherical shapes and their optical properties differ significantly due to changes in localized plasmon excitation. We demonstrate experimentally and support theoretically three-dimensional confinement of large gold nanoparticles in an optical trap based on very low numerical aperture optics. We showed theoretically that the unique properties of gold nanoprisms allow an increase of trapping force by an order of magnitude at certain aspect ratios. These results pave the way to spatial manipulation of plasmonic nanoparticles using an optical fibre, with interesting applications in biology and medicine.
Indo-China Monsoon Indices
Authors: Tsai ChinLeong , Behera Swadhin K. , Waseda Takuji 
Published: January 2015

AbstractMyanmar and Thailand often experience severe droughts and floods that cause irreparable damage to the socio-economy condition of both countries. In this study, the Southeastern Asian Summer Monsoon variation is found to be the main element of interannual precipitation variation of the region, more than the El Niño/Southern Oscillation (ENSO). The ENSO influence is evident only during the boreal spring season. Although the monsoon is the major factor, the existing Indian Monsoon Index (IMI) and Western North Pacific Monsoon Index (WNPMI) do not correlate well with the precipitation variation in the study regions of Southern Myanmar and Thailand. Therefore, a new set of indices is developed based on the regional monsoon variations and presented here for the first time. Precipitation variations in Southern Myanmar and Thailand differ as well as the elements affecting the precipitation variations in different seasons. So, separate indices are proposed for each season for Southern Myanmar and Thailand. Four new monsoon indices based on wind anomalies are formulated and are named as the Indochina Monsoon Indices. These new indices correlate better with the precipitation variations of the study region as compared to the existing IMI and WNPMI.
RETRACTED ARTICLE: Association between cytochrome P450 1A1 (CYP1A1) gene polymorphisms and the risk of renal cell carcinoma: a meta-analysis
Authors: Meng Fan-dong , Ma Ping , Sui Cheng-guang , Tian Xin , Jiang You-hong 
Published: January 2015

Abstract
Cytochrome P450 1A1 (CYP1A1) usually metabolizes carcinogens to their inactive derivatives but occasionally converts the chemicals to more potent carcinogens. To date, many studies have evaluated the association between the CYP1A1 MspI and Ile462Val polymorphisms and renal cell carcinoma (RCC) risk, but the results have been conflicting. To more precisely evaluate the potential association, we carried out a meta-analysis of seven published case-control studies. The meta-analysis indicated that the MspI polymorphism was associated with an increased RCC risk (allele model: OR = 1.49, 95%CI 1.03–2.16; homozygous model: OR = 1.64, 95%CI 1.13–2.40; dominant model: OR = 1.72, 95%CI 1.07–2.76). No significant associations were found for the Ile462Val polymorphism for all genetic models. When stratified by smoking status, smokers carrying the variant Vt and Val allele were more susceptible to RCC (Vt allele: OR = 3.37, 95%CI = 2.24–5.06; Val allele: OR = 2.07, 95%CI = 1.34–3.19). These data indicate that the CYP1A1 MspI polymorphism significantly increased RCC risk, while the Ile462Val polymorphism was not associated with RCC. Among smokers, individuals with the CYP1A1 Vt allele and Val allele showed a significantly increased risk of RCC. More well-designed studies with larger samples are warranted to show the underlying mechanisms of CYP1A1 in the development of RCC.
Glycerol-3-phosphate O-acyltransferase is required for PBAN-induced sex pheromone biosynthesis in Bombyx mori
Authors: Du Mengfang , Liu Xiaoguang , Liu Xiaoming , Yin Xinming , Han Shuangyin , Song Qisheng , An Shiheng 
Published: January 2015

AbstractFemale moths employ their own pheromone blends as a communicational medium in mating behavior. The biosynthesis and release of sex pheromone in female moths are regulated by pheromone biosynthesis activating neuropeptide (PBAN) and the corresponding action of PBAN has been well elucidated in Bombyx mori. However, very little is known about the molecular mechanism regarding the biosynthesis of sex pheromone precursor. In this study, quantitative proteomics was utilized to comprehensively elucidate the expression dynamics of pheromone glands (PGs) during development. Proteomic analysis revealed a serial of differentially expressed sex pheromone biosynthesis-associated proteins at the different time points of B. mori development. Most interestingly B. mori glycerol-3-phosphate O-acyltransferase (BmGPAT) was found to be expressed during the key periods of sex pheromone biosynthesis. RNAi knockdown of BmGPAT confirmed the important function of this protein in the biosynthesis of sex pheromone precursor, triacylglcerol (TAG) and subsequently PBAN-induced production of sex pheromone, bombykol. Behavioral analysis showed that RNAi knockdown of GPAT significantly impaired the ability of females to attract males. Our findings indicate that GPAT acts to regulate the biosynthesis of sex pheromone precursor, TAG, thus influencing PBAN-induced sex pheromone production and subsequent mating behavior.