bluuebunny/crossref_metadata_2025_split huggingface dataset:
Immigration, dynamiques socio-économiques territoriales et mouvements résidentiels. Quelles perspectives pour les résidents du Luxembourg ?
Authors: Lord Sébastien , Gerber Philippe 
Published: May 2013

Immigration, socio-economic territorial dynamics and residential mouvements. What perspectives for the residents of Luxembourg?	L’immigration est au centre de la croissance économique et du développement social du Luxembourg. On retrouve dans le pays d’importants écarts entre certains sous-groupes d’étrangers hautement qualifiés opposés à d’autres moins formés, s’ajoutant aux inégalités socio-économiques déjà présentes dans la population nationale. Dans cet article, nous nous intéressons à l’évolution des inégalités sociales dans un contexte d’immigration, en nous focalisant sur la dimension longitudinale. Nous explorons, avec le dernier recensement national exhaustif, l’évolution des territoires communaux luxembourgeois du point de vue socio-économique pour voir comment les mouvements résidentiels des populations nationales et étrangères ont, dans l’espace social et spatial, suivi ou non la tendance de prospérité qui a marqué le pays dans les dernières décennies. Dans un premier temps, nous construisons une série de portraits descriptifs sur l’évolution des communes à la lumière de la mobilité résidentielle et de l’immigration. Ces portraits montrent que les inégalités sociales et spatiales se sont principalement structurées autour de la capitale et ses communes périurbaines en tant que territoires privilégiés, et le sud comme territoire plus précarisé. Dans un deuxième temps, à travers une série de modèles probabilistes, notre exploration permet d’isoler de manière dynamique l’implication explicite de l’immigration qualifiée et moins qualifiée dans l’évolution des territoires. L’arrivée d’étrangers marque ainsi fortement la structure socio-spatiale du territoire luxembourgeois.
Cathedral of Kairos:
Authors: Benjamin Crosby Richard 
Published: May 2013

ABSTRACTTraditionally, kairos is defined by its transience. Scholars assume that in order to capitalize on the rhetorical power of kairos, a speaker must capture the “opportune moment” before it passes. This article makes the case that the kairic moment can be sustained indefinitely through the sacralization of physical space. Linking rhetorical theories of kairos as “God's time” to Mircea Eliade's discussion of “sacred hierophanies,” the article performs an analysis of the National Cathedral in Washington DC and concludes that rhetoric can circumvent traditional contingencies when deployed within kairic space.
The Reasonable and the Sensible:
Authors: Kraemer Don J. 
Published: May 2013

ABSTRACTJoining the New Rhetoric project's conversation about argumentation as justice, this article aims to add an expanded version of the psychological to the just resources of argumentation. After examining how Perelman and Olbrechts-Tyteca's The New Rhetoric justifies attention to—yet ultimately swerves from—contingencies of psycho-physical sensation, I turn to Burke's highly elaborated concept of identification, which adds to the New Rhetoric project by articulating the relations of physiological sensation, attitude and emotion, and persuasion. Linking ethics and form, identification provides a means by which one may grow increasingly aware of the sensation-driven defensiveness that can undermine dialogic exchange. After making this case that Burke's rhetoric can help develop what is not in the New Rhetoric project but should be—the resource of constitutive, affective identification—I end with what should be in Burke but is not—a universality that a “we” of substantially different constitutions would agree on.
Identification of Risk Factors for Recurrence in High-Risk Stage II Colon Cancer
Authors: Hatano Satoshi , Ishida Hideyuki , Ishibashi Keiichiro , Kumamoto Kensuke , Haga Norihiro , Miura Ichiro 
Published: May 2013

Abstract
To identify risk factors for recurrence in patients with stage II colon cancer, Cox proportional hazards regression analysis was performed in 194 patients with stage II colon cancer who underwent curative surgery between April 1997 and December 2008. Thirteen clinical and pathologic factors, including use of fluoropyrimidine-based adjuvant chemotherapy in 113 of the patients (58.2%), were assessed. By multivariate analysis, only obstruction, perforation, and T4-level invasion were identified as independent risk factors affecting disease-free survival (DFS) (P &lt; 0.01). The 5-year DFS rate was 70.6% in patients with one or more risk factors (n = 68) and 96.0% in patients with no risk factors (n = 126) (P &lt; 0.01). These results suggest that obstruction, perforation, and T4-level invasion are suitable candidates for prediction of tumor recurrence in patients with stage II colon cancer. The oxaliplatin-based adjuvant chemotherapy, which has been reported to be effective in stage III colon cancer patients, may improve the prognosis in high-risk stage II colon cancer patients.
A Stand-Alone Synbiotic Treatment for the Prevention of D-Lactic Acidosis in Short Bowel Syndrome
Authors: Takahashi Kazuhiro , Terashima Hideo , Kohno Keisuke , Ohkohchi Nobuhiro 
Published: May 2013

Abstract
Synbiotics are combinations of probiotics and prebiotics that have recently been used in the context of various gastrointestinal diseases, including infectious enteritis, inflammatory bowel disease, and bowel obstruction. We encountered a patient with recurrent D-lactic acidosis who was treated successfully for long periods using synbiotics. The patient was diagnosed as having short bowel syndrome and had recurrent episodes of neurologic dysfunction due to D-lactic acidosis. In addition to fasting, the patient had been treated with antibiotics to eliminate D-lactate–producing bacteria. After the failure of antibiotic treatment, a stand-alone synbiotic treatment was started, specifically Bifidobacterium breve Yakult and Lactobacillus casei Shirota as probiotics, and galacto-oligosaccharide as a prebiotic. Serum D-lactate levels declined, and the patient has been recurrence-free for 3 years without dietary restriction. Synbiotics allowed the reduction in colonic absorption of D-lactate by both prevention of D-lactate–producing bacterial overgrowth and stimulation of intestinal motility, leading to remission of D-lactate acidosis.
Drug Susceptibility Testing Guided Treatment for Drug-Resistant Spinal Tuberculosis: A Retrospective Analysis of 19 Patients
Authors: Xu Lan , Jian-Zhong Xu , Xue-Mei Liu , Bao-Feng Ge 
Published: May 2013

Abstract
Spinal tuberculosis is the most common manifestation of extrapulmonary tuberculosis. However, there have been few reports on the topic of drug-resistant spinal tuberculosis. The aim of this study was to investigate the efficacy and safety of treatment with a combination of surgery and individual chemotherapy guided by drug susceptibility testing for drug-resistant spinal tuberculosis. We retrospectively analyzed 19 patients with drug-resistant spinal tuberculosis. After surgery, individual chemotherapy was tailored for each patient according to his or her drug resistance profile and previous history of chemotherapy. The patients were followed up clinically and radiologically for an average period of 36 months. Among 19 drug-resistant spinal tuberculosis cases, 16 were multidrug-resistant tuberculosis (MDR-TB), and 3 were non–MDR-TB. The patients with MDR-TB and non–MDR-TB had undergone previous chemotherapy for an average of 12.50 ± 2.00 months (0–55 months) and 5.50 ± 1.20 months (0–60 months), respectively. A total of 16 patients underwent open operations, and the other 3 had percutaneous drainage and local chemotherapy. Patients received individual chemotherapy for an average of 24 months postoperatively. All patients had been cured at the final follow-up. Drug-resistant spinal tuberculosis is mainly acquired through previous irregular chemotherapy and the spread of drug-resistant strains. Treatment with a combination of surgery and individual chemotherapy is feasible in the treatment of severe complications and the prevention of acquired drug resistance.
Storage of Allogeneic Vascular Grafts: Experience From a High-Volume Liver Transplant Institute
Authors: Aydin Cemalettin , Ince Volkan , Otan Emrah , Akbulut Sami , Koc Cemalettin , Kayaalp Cuneyt , Yilmaz Sezai 
Published: May 2013

Abstract
Allogeneic vascular grafts are often required for vascular reconstruction during living donor liver transplantation. Such grafts are obtained prior to use, making storage conditions a critical issue for maintaining the integrity of the tissue to ensure a successful transplantation. This study describes an optimized storage protocol currently in use at a high-volume liver transplant center. Twenty-nine allogeneic vascular graft tissues obtained during cardiovascular surgery or from cadaveric donors were stored respectively in sterile 50 mL of Ringer lactate solution, without any preservation solutions or antimicrobials, at −22°C for a maximum of 3 months. Prior to use in vascular reconstruction, grafts were thawed in 0.9% NaCl solution at 37°C, and 1 × 0.5-cm2 tissue samples were collected for microbial culturing and viral serology. ABO compatibility was not performed for any patients receiving vascular grafts. During this prospective study, all 29 allogeneic vascular grafts were used for back-table vascular reconstruction in living donor liver transplantation procedures. A total of 16 grafts were from the saphenous vein, 10 were from the iliac vein, and 3 were from the iliac artery. Bacterial growth was not detected in any tissue samples taken from the stored grafts. No vascular graft-related complications occurred during the 5 months of follow-up. The successful vascular reconstructions achieved with all 29 study grafts demonstrate that the simple, inexpensive storage method described herein is feasible and safe. Randomized, controlled studies should be carried out to further optimize and standardize the technique.
Bottom‐Up Synthesis of Bis(triisopropylsilyl)ethynyl Hexaphyrin Bearing an Unsubstituted meso‐Carbon
Authors: Mori Hirotaka , Naoda Koji , Osuka Atsuhiro 
Published: May 2013

Abstract3,7‐Dibromo‐10,15,20,25,30‐pentakis(pentafluorophenyl)hexaphyrin (3) and 3,7‐bis(triisopropylsilyl)‐10,15,20,25,30‐pentakis(pentafluorophenyl)hexaphyrin (4) were synthesized by a stepwise route, in which prefunctionalized dipyrromethane Sn4+ complexes serve as key precursors. Hexaphyrins 3 and 4 have rectangular structures with an unsubstituted meso position on the shorter side. These hexaphyrins are stable in air.
Exogenous 1,4‐butyrolactone stimulates A‐factor‐like cascade and validamycin biosynthesis in Streptomyces hygroscopicus 5008
Authors: Tan Gao‐Yi , Bai Linquan , Zhong Jian‐Jiang 
Published: May 2013

ABSTRACTγ‐Butyrolactones (GBLs), such as A‐factor, are one type of signaling molecules produced by Streptomyces species and have been reported to regulate secondary metabolism. However, they are usually produced in very small amount, which has hindered their structural elucidation and application for antibiotic overproduction. In this work, 1,4‐butyrolactone (1,4‐BL), as an easily accessible and cheap analogue of GBLs, was applied to the fermentation of validamycin A (VAL‐A), an important antifungal antibiotic produced by Streptomyces hygroscopicus 5008. The addition of 1,4‐BL enhanced VAL‐A production by 30% in both shaking flasks and bioreactors. The transcriptional levels of the adpA homologue (adpA–H) and VAL‐A biosynthetic genes were significantly increased. Among the three A‐factor receptor homologous genes identified in the genome of S. hygroscopicus 5008, shbR3 was proved to be responsible for the inducing activity of 1,4‐BL by gene disruption and circular dichroism analysis, and ShbR3 could bind to the promoter region of adpA–H as indicated by EMSA analysis. Furthermore, the mutation of adpA–H abolished the transcription of VAL‐A biosynthetic genes and VAL‐A productivity. In EMSA analysis, AdpA–H could directly bind to the promoter regions of VAL‐A gene cluster. Moreover, addition of the 1,4‐BL also improved the VAL‐A production in a high‐yielding strain TL01. The results showed that 1,4‐BL could stimulate A‐factor‐like cascade and subsequently enhance VAL‐A production in S. hygroscopicus 5008. Biotechnol. Bioeng. 2013;110: 2984–2993. © 2013 Wiley Periodicals, Inc.
Transdisciplinary Research in Sustainable Operations – An Application to Closed‐Loop Supply Chains
Authors: Sahamie Ramin , Stindt Dennis , Nuss Christian 
Published: May 2013

ABSTRACTThis contribution provides implications for academic research and practitioners, as it identifies the lack, necessity and major benefits of transdisciplinary research and the collaboration of academics and industry in order to fulfill the goals of a sustainable supply chain. Closed‐loop supply chain management is a major contributor to implementing sustainable operations. An essential prerequisite for successful realization is the expertise and cooperation of representatives from engineering, management and natural sciences as well as practice. We identify a need for transdisciplinary collaboration within two steps. First, a literature review points out that various research disciplines as well as practice mostly operate in isolation. Second, we develop a framework that highlights the benefits of collaboration between these research areas. This paper provides an overview to better understand current trends in this complex field, which is a rich area for research that is still in its infancy. Copyright © 2013 John Wiley & Sons, Ltd and ERP Environment
ChemInform Abstract: Crystal Structure and Phase Transition Mechanisms in CsFe2F6.
Authors: Molokeev M. S. , Bogdanov E. V. , Misyul S. V. , Tressaud A. , Flerov I. N. 
Published: May 2013

AbstractSingle crystals of CsFe2F6 are obtained by solid state reaction of a stoichiometric mixture of CsF, FeF2, and FeF3 (sealed Pt crucible, 750 °C, controlled cooling).
ChemInform Abstract: Structural and Magnetic Properties of the M2Ga2Fe2O9 (M: In, Sc) Oxides.
Authors: Ciomaga Hatnean Monica , Pinsard‐Gaudart Loreynne , Fernandez‐Diaz Maria Theresa , Petit Sylvain , Dixit Ambesh , Lawes Gavin , Suryanarayanan R. 
Published: May 2013

AbstractIn2Ga2Fe2O9 and Sc2Ga2Fe2O9 are prepared by solid state reaction of stoichiometric mixtures of M2O3 (M: In, Sc), Ga2O3, and Fe2O3 (air, 11375—1400 °C, 24—30 h).
ChemInform Abstract: Investigation of a New Willemite‐Type Compound, (Li, Na, H)0.16Zn1.92SiO4.
Authors: Park S.‐H. , Chucholowski C. J. , Lara L. Garcia B. , Hoelzel M. , Paulmann C. 
Published: May 2013

AbstractThe title compound is synthesized by solid state reaction of SiO2, ZnO, Li2CO3, and Na2CO3 using an optimized ratio of 1:0.63:0.04:0.13 resp.
ChemInform Abstract: The Dimeric [V2O2F8]4‐ Anion: Structural Characterization of a Magnetic Basic‐Building‐Unit.
Authors: Lu Hongcheng , Gautier Romain , Li Zuo‐Xi , Jie Wanqi , Liu Zhengtang , Poeppelmeier Kenneth R. 
Published: May 2013

AbstractGreen single crystals of [dpaH2]2[V2O2F8] are prepared by hydrothermal reaction of 2,2′‐dipyridylamine (dpa) and VO2 in aqueous HF (200 °C, 24 h).
ChemInform Abstract: A Simple Metal‐Promoted Three‐Step Access to n/5/m Angular Carbocyclic Systems
Authors: Barluenga Jose , Alvarez‐Fernandez Ana , Suarez‐Rodriguez Tatiana , Suarez‐Sobrino Angel L. , Tomas Miguel 
Published: May 2013

Abstractusing a cyclopentannulation of propargylmalonates and Fischer carbenes as key step
ChemInform Abstract: An Ullmann C—O Coupling Reaction Catalyzed by Magnetic Copper Ferrite Nanoparticles.
Authors: Yang Shuliang , Wu Cunqi , Zhou Hua , Yang Yanqin , Zhao Yongxia , Wang Chenxu , Yang Wei , Xu Jingwei 
Published: May 2013

AbstractAn efficient Ullmann C—O coupling reaction is developed, which tolerates a wide range of different functional groups.
ChemInform Abstract: Heterocoupling of 2‐Naphthols Enabled by a Copper‐N‐heterocyclic Carbene Complex.
Authors: Holtz‐Mulholland Michael , de Leseleuc Mylene , Collins Shawn K. 
Published: May 2013

AbstractThe reactivity of a Cu‐NHC‐catalyst for oxidative coupling is modulated by a small molecule additive, diethyl malonate, that slows over‐oxidation of 2‐naphthols (I) and (II).
ChemInform Abstract: Aerobic Dehydrogenative Heck Reactions of Heterocycles with Styrenes: A Negative Effect of Metallic Co‐Oxidants.
Authors: Vasseur Alexandre , Harakat Dominique , Muzart Jacques , Le Bras Jean 
Published: May 2013

AbstractAerobic dehydrogenative Heck reactions of heterocycles with styrene derivatives are shown to be more efficient in the absence of metallic co‐oxidants.
ChemInform Abstract: An Entry to Polysubstituted Furans via the Oxidative Ring‐Opening of Furan Ring Employing NBS as an Oxidant.
Authors: Yu Huiyue , Zhong Weiqiang , He Tingyu , Gu Wenxiang , Yin Biaolin 
Published: May 2013

AbstractThe reaction proceeds through NBS‐mediated oxidative dearomatization of the furan ring followed by spirocyclization and aromatization.
ChemInform Abstract: Tandem Reaction Between Chalcone Epoxides and 2‐Naphthyl Ethers to Construct Complex Naphtho[2,1‐b]furans.
Authors: Huo Congde , An Jinzhu , Xu Xiaolan , Jia Xiaodong , Wang Xicun , Kang Lisheng 
Published: May 2013

AbstractAnnulation of 2‐naphthyl ethers with chalcone epoxides in the presence of a stable triarylium hexachloroantimonate is followed by aerobic oxidative aromatization.
ChemInform Abstract: Convenient Method for the Preparation of the 2‐Methyl Thiophen‐3‐yl Magnesium Bromide Lithium Chloride Complex and Its Application to the Synthesis of 3‐Substituted 2‐Methylthiophenes.
Authors: Kogami Masakazu , Watanabe Nobuhide 
Published: May 2013

AbstractLiCl significantly accelerates the formation of Grignard reagent from inactive 3‐bromo‐2‐methylthiophene (I) and thus provides access to a variety of 3‐substituted 2‐methylthiophenes (15 examples).
ChemInform Abstract: Iron Sulfide Catalyzed Redox/Condensation Cascade Reaction Between 2‐Amino/Hydroxy Nitrobenzenes and Activated Methyl Groups: A Straightforward Atom Economical Approach to 2‐Hetarylbenzimidazoles and ‐benzoxazoles.
Authors: Nguyen Thanh Binh , Ermolenko Ludmila , Al‐Mourabit Ali 
Published: May 2013

AbstractThe reaction does not require any oxidizing or reducing agent and proceeds without any solvent.
ChemInform Abstract: A New and Efficient Synthesis of 1,3,4‐Oxadiazole Derivatives Using TBTU.
Authors: Maghari Shokoofeh , Ramezanpour Sorour , Darvish Fatemeh , Balalaie Saeed , Rominger Frank , Bijanzadeh Hamid Reza 
Published: May 2013

AbstractThis is a simple and environmentally benign procedure with mild reaction conditions compared to other reported methods.
ChemInform Abstract: Discovery of Novel 1,4‐Dihydropyridine‐Based PDE4 Inhibitors.
Authors: Poondra Rajamohan R. , et al. et al. 
Published: May 2013

AbstractA series of novel 1,4‐dihydropyridine derivatives (IV) (30 examples) are synthesized via a modified Hantzsch reaction and evaluated for their inhibitory potencies against phosphodiesterase 4.
ChemInform Abstract: Synthesis of 7‐Cycloalkylimino Substituted 3‐Amino‐6‐fluoro‐2‐methyl‐3H‐quinazolin‐4‐ones.
Authors: Nosova Emiliya V. , Lipunova Galina N. , Slepukhin Pavel A. , Charushin Valery N. 
Published: May 2013

AbstractThe title compounds (V) are obtained by nucleophilic amination‐defluorination reaction of the 6,7‐difluoro derivative of 3‐amino‐2‐methyl‐3H‐quinazolin‐4‐one (III).
ChemInform Abstract: One‐Pot Synthesis of Unsymmetrical Benzils and N‐Heteroarenes Through Nucleophilic Aroylation Catalyzed by N‐Heterocyclic Carbene.
Authors: Suzuki Yumiko , Murofushi Mai , Manabe Kei 
Published: May 2013

AbstractN‐phenylbenzimidoyl chlorides (I) are readily obtained by chlorination of benzanilides.The method is applied to the synthesis of quinoxalines (IV) and pyrazines (VII).
ChemInform Abstract: Synthesis and Biological Evaluation of 1‐(6‐Methylpyridin‐2‐yl)‐5‐(quinoxalin‐6‐yl)‐1,2,3‐triazoles as Transforming Growth Factor‐β Type 1 Receptor Kinase Inhibitors.
Authors: Li Fei , Park Yunjeong , Hah Jung‐Mi , Ryu Jae‐Sang 
Published: May 2013

AbstractA variety of the title triazole derivatives (VI) (11 examples) are designed, synthesized using click chemistry, and evaluated as novel ALKS inhibitors.
ChemInform Abstract: Hydration of Terminal Alkynes Catalyzed by Water‐Soluble Cobalt Porphyrin Complexes.
Authors: Tachinami Tadashi , Nishimura Takuho , Ushimaru Richiro , Noyori Ryoji , Naka Hiroshi 
Published: May 2013

AbstractThe reaction represents the first example of the cobalt‐catalyzed hydration of alkynes.
ChemInform Abstract: Lysilactones A—C (Ia‐c), Three 6H‐Dibenzo[b,d]pyran‐6‐one Glycosides from Lysimachia clethroides, Total Synthesis of Lysilactone A (Ia).
Authors: Liang Dong , Luo Huan , Liu Yan‐Fei , Hao Zhi‐You , Wang Yan , Zhang Chun‐Lei , Zhang Qing‐Jian , Chen Ruo‐Yun , Yu De‐Quan 
Published: May 2013

AbstractThis is the first report of 6H‐dibenzo[b,d]pyran‐6‐one glycosides from natural sources.
Caudo‐rostral brain spreading of α‐synuclein through vagal connections
Authors: Ulusoy Ayse , Rusconi Raffaella , Pérez‐Revuelta Blanca I. , Musgrove Ruth E. , Helwig Michael , Winzen‐Reichert Bettina , Monte Donato A. Di 
Published: May 2013

Abstractα‐Synuclein accumulation and pathology in Parkinson's disease typically display a caudo‐rostral pattern of progression, involving neuronal nuclei in the medulla oblongata at the earliest stages. In this study, selective expression and accumulation of human α‐synuclein within medullary neurons was achieved via retrograde transport of adeno‐associated viral vectors unilaterally injected into the vagus nerve in the rat neck. The exogenous protein progressively spread toward more rostral brain regions where it could be detected within axonal projections. Propagation to the pons, midbrain and forebrain followed a stereotypical pattern of topographical distribution. It affected areas such as the coeruleus–subcoeruleus complex, dorsal raphae, hypothalamus and amygdala ipsilateral and, to a lesser extent, contralateral to the injection side. Spreading was accompanied by evidence of neuritic pathology in the form of axonal varicosities intensely immunoreactive for human α‐synuclein and containing Thioflavin‐S‐positive fibrils. Thus, overexpression of human α‐synuclein in the lower brainstem is sufficient to induce its long‐distance caudo‐rostral propagation, recapitulating features of Parkinson's disease and mechanisms of disease progression.