bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGARUH BERWUDHU TERHADAP TINGKAT KECEMASAN SUAMI DALAM MENGHADAPI ISTRI PRE OPERASI SECTIO CAESAREA DI RS MAWADDAH MEDIKA
Authors: Yulianti Indra , Tri Ratnaningsih  , Amar Akbar  
Published: July 2024

Pendahuluan: Fenomena dalam menghadapi persiapan dan tindakan operasi sectio caesarea banyak ditemui suami yang mengalami kecemasan. Suami merupakan orang terdekat dengan istri, sehingga menghadapi istri yang akan menjalni sectio caesarea suami akan merasakan cemas. Cara non farmakologis menurunkan kecemasan adalah teknik relaksasi, psikoterapi dengan hipnoterapi dan hidroterapi, Salah satunya dengan berwudhu. Tujuan: mengetahui Pengaruh Berwudhu Terhadap Tingkat Kecemasan Suami Dalam Menghadapi Istri Pre Operasi Sectio Caesarea di RS Mawaddah Medika. Metode: menggunakan quasy experimental dengan pendekatan control group pretest-post test design. Populasi dalam penelitian ini adalah semua suami yang sedang menghadapi istri pre operasi SC di RS Mawaddah Medika pada bulan Mei 2023 sebanyak 58 orang. Teknik sampling penelitian ini adalah consecutive sampling dengan kurun waktu 1 bulan. Besar sampel yang memenuhi kriteria penelitian adalah 32 orang yang terbagi menjadi 16 orang kelompok eksperimen dan 16 orang kelompok kontrol. Instrumen penelitian menggunakan SOP berwudhu dan kuesioner HARS. Hasil: sebelum berwudhu sebagian besar responden pada kelompok eksperimen mengalami kecemasan sedang yaitu 11 orang (69,8%), dan sesudah berwudhu sebagian besar responden pada kelompok eksperimen mengalami kecemasan ringan yaitu 11 orang (69,8%). Hasil uji Paired t test menunjukkan rata-rata skor kecemasan responden sebelum berwudhu sebesar 23,25 dan sesudah berwudhu sebesar 19,81 sehingga terjadi penurunan skor kecemasan dengan pvalue=0,000. Kesimpulan: Wudhu memberikan akupresur pada ratusan titik akupunktur yang bersifat reseptor terhadap stimulus berupa basuhan, gosokan, usapan, dan tekanan/urutan dengan menggunakan air akan menghasilkan terapi akupresur dan hidroterapi yang dapat mengurangi kekejangan menjadi rileks.
Penanaman Moral dan Adab Sesuai dengan Sila Kedua Pancasila di SDN 8 Langkai Kota Palangka Raya
Authors: Misyanto Misyanto , Rozikin Achmad Zainul , Astuti Amelia Dwi , Robiyanoor Robiyanoor , Wirayuda Aldi , Ansyahrin Alfi , Aulia Aulia , Sihotang Muliana Sarah Abigael Boru , Fitria Nor Aida , Ilham Tiara Salaysha Fatihah 
Published: July 2024

Pancasila merupakan dasar sekaligus sebagai ideologi bangsa Indonesia menegakkan prinsip-prinsip kehidupan bernegara. Dalam menerapkan nilai-nilai sila ke-II Pancasila siswa menanamkan dan menerapkan secara nyata di lingkungan sekolah dan masyarakat. Pengabdian masyarakat ini bertujuan untuk menguatkan nilai nilai sila ke-II Pancasila. Adapun metode yang digunakan dalam pengabdian masyarakat ini yaitu berupa sosialisasi kepada siswa kelas VI SDN 8 Langkai Kota Palangka Raya. Sosialisasi merupakan suatu proses sosial yang dialami seseorang atau kelompok untuk belajar mengenali serta menghayati pola perilaku, sistem sosial terkait nilai dan norma. Hasil dari sosialisasi yang sudah kami lakukan menunjukkan bahwa rata rata siswa sudah menerapkan nilai sila ke-II Pancasila pada kehidupan sehari-hari terutama dilingkungan sekolah. Sehingga dapat disimpulkan bahwa siswa kelas VI SDN 8 Langkai Kota Palangka Raya sudah mendapatkan sosialisasi tentang nilai-nilai sila ke-II Pancasila dan menerapkannya di kehidupan sehari-hari.
Pengaruh Penerapan Model Pembelajaran Problem Based Learning terhadap Hasil Belajar Mapel Ekonomi Kelas X di SMAN 2 Sijunjung
Authors: Supriyanti Juli , Hendrita Vivi , Alatas Andi , Syuhada Fildza Arief 
Published: July 2024

Penelitian ini bertujuan untuk mengetahui sejauh mana pengaruh dari siswa yang diajar dengan model pembelajaran problem based learning lebih tinggi hasil belajar mata pelajaran ekonomi dibandingkan siswa yang diajar dengan model pembelajaran konvensional kelas X di SMAN 2 Sijunjung. Jenis penelitian ini adalah penelitian quasi eksperimen dengan menggunakan dua kelas penelitian yaitu kelas kontrol dan kelas eksperimen. Jumlah sampel penelitian dari kedua kelas adalah 66 orang siswa. Teknik pengumpulan untuk hasil belajar berupa tes dalam bentuk pilihan berganda yang diberikan diakhir pembelajaran. Teknik analisis data dilakukan uji persyaratan analisis data dan hipotesis dengan Anova dua jalur. Hasil penelitian menunjukkan bahwa hasil belajar mata pelajaran ekonomi pada siswa yang diajarkan dengan model pembelajaran problem based learning lebih tinggi daripada siswa yang diajarkan dengan menggunakan model pembelajaran konvensional di kelas X SMAN 2 Sijunjung. hasil uji menunjukkan bahwa nilai thitung 5,453 dan nilai probabilitas 0,000. Sehingga nilai probabilitas 0,000<0,05 maka H0 ditolak. Hal ini berarti bahwa hasil belajar ekonomi siswa yang diajar dengan model pembelajaran problem based learning secara signifikan lebih tinggi dari pada hasil belajar ekonomi siswa yang diajarkan dengan model pembelajaran konvensional pada taraf signifikansi 0,05.
Efforts to improve mathematics learning outcomes using the Realistic Mathematics Education (RME) learning model assisted by student number card media Class IV SDN-1 New Kasongan
Authors: Estimurti Endang Sri , Sriwihartati Yuni 
Published: July 2024

Background: Mathematics is a universal science that underlies the development of modern technology, has an important role in various disciplines and advances human thinking. There are still many students who seem less motivated, The results of initial observations at SDN-I Kasongan Baru show that interest in learning is low and tends to do things that are beyond their obligations as students, both in the learning process in class and outside the classroom. So the researcher concluded the need to apply a realistic mathematics education learning model assisted by card media to improve student learning outcomes. Objectives: This study aims to: (1) Determine the Mathematics learning activities of students and teachers using the Realistic Mathematics Education (RME) learning model in grade IV SDN-1 Kasongan Baru, (2) find out the improvement of learning outcomes with the Realistic Mathematics Education (RME) learning model. Method: This study uses the type of PTK research with the Realistic Mathematics Education (RME) research model. This research was carried out in grade IV of SDN-1 Kasongan Baru in the even semester of the 2023 academic year with the subjects of the study being 21 grade IV students. Data collection is carried out by Observation and Test methods. Data analysis uses qualitative and quantitative. Results and Dıscussion: The results showed that: 1) teacher and student activity after the observation results in cycle I showed that the average activity score of teachers and students was in the range of scale 2.7 and 2.9 with a fairly good category while in cycle II the observation results of teachers and students increased in the range of 3.3 and 3.3 with good category, 2) there is an improvement in Mathematics learning outcomes after applying the Realistic Mathematics Education (RME) learning model in grade IV SDN-1 Kasongan Baru. Conclusion: The realistic Mathematics Education (RME) learning model assisted by number card media can improve the mathematics learning outcomes of grade IV students of SDN-I Kasongan Baru.
KONSEP 4P SEBAGAI STRATEGI RUMAH MAKAN CAHAYA MINANG DALAM MEMPERTAHANKAN USAHANYA (Studi Kasus pada Kampung Hambulu Kabupaten Bogor)
Authors: Niluth Niluth 
Published: July 2024

Persaingan merupakan hal yang lazim ada di setiap bisnis yang dilakukan. Rumah Makan Cahaya Minang juga mempunyai pesaing yang sesuai dengan bidangnya. Rumah Makan Cahaya Minang membutuhkan beberapa strategi agar tetap bisa bersaing dengan rumah makan lain dengan menerapkan pedoman-pedoman persaingan secara sehat. Seiring dengan pesatnya pertumbuhan pertambahan jumlah penduduk maka pemenuhan kebutuhan pangan semakin bertambah. Hal tersebut membuka peluang para pelaku usaha untuk membuka rumah makan. Dari tahun ke tahun pelaku usaha untuk membuka rumah makan semakin bertambah. Tujuan penelitian ini adalah untuk mengetahui Strategi Marketing Mix Menggunakan Konsep 4p (Price, Product, Place, Promotion) Pada Rumah Makan Cahaya Minang. Pendekatan penelitian yang dilakukan adalah pendekatan kualitatif. Sumber data berasal dari data primer dan sekunder. Teknik pengumpulan data yang dilakukan adalah dengan wawancara kepada pemilik atau pengelola dari Rumah makan cahaya minang. Berdasarkan penelitian yang dilakukan, menghasilkan kesimpulan bahwa Rumah makan cahaya minang sudah menggunakan strategi marketing mix dalam perusahaan. Konsep 4p yang digunakan seperti: 1. Produk yaitu dengan memperhatikan kualitas produk yang baik, kebersihan produk, dan cita rasa yang enak akan membuat produk semakin menarik dan menambah minat beli konsumen. 2. Harga yang dapat dijangkau oleh pelanggaran agar produknya dapat dinikmati oleh semua kalangan manapun. 3. Tempat yaitu dengan memilih lokasi sangat strategi yang dimana banyak orang melintas dan bisa memudahkan pelanggan untuk datang membeli produk rumah makan cahaya minang. 4. Promosi dalam rumah makan cahaya minang melalui media sosial seperti whatsApp, facebook dan juga pemasaran langsung. Dari permasalahan tersebut analisis SWOT (Strength, Weakness, Opportunity, Threats) dan strategi 4P (Product, Price, Place, Promotion), hal ini penting dalam rangka. Merumuskan rencana pengelolaan strategis yang akan dilaksanakan oleh rumah makan cahaya minang. Implementasi startegi pemasaran berupa rumah makan yang memanfaatkan kualitas produk sesuai dengan 4p. Pengaruh promosi dan harga terhadap peningkatan penjualan yaitu sangat berpengaruh. Dapat dilihat dari hasil perhitungan 4p yaitu pengaruh promosi (gencar dalam melakukan promosi dan pemasaran) dan harga (produk terjangkau bagi konsumen di segala kalangan) terhadap penjualan. Kata Kunci: Strategi Pengembangan; Konsep 4p; Analisis SOWT
Penerapan Tehnik Stek Akar Untuk Pengembangan Tanaman Sukun (Artocarpus altilis) di Lahan Kebun Pendidikan (Agrotechno Park) Kampus IV Universitas Khairun
Authors: Umasugi Buhari , Teapon Amiruddin , Hartono Gunawan 
Published: July 2024

Pengembangan tanaman Sukun (Artocarpus altilis) di Lahan Kebun Pendidikan Kampus IV Universitas Khairun membutuhkan ketersediaan adanya anakan/bibit sukun. Anakan sukun dari berbagai varietas sukun di Provinsi Maluku Utara berlum tersedia secara lokal di Dusun Bangko Desa Bobaneigo Madihutu yang merupakan lokasi Pengembangan. Kegiatan ini bertujuan untuk dilakukan pemberdayaan petani lokal dalam mengembangkan bibit sukun melalui tehnik stek akar. Metode pelaksanaan kegiatan PKM ini akan berlangsung selama 6 bulan pada tahun 2023 yang berlokasi di Dusun Bango Desa Bobeneigo Maduhutu, Kecamatan Jailolo Selatan Kabupaten Halmahera Barat. Metode yang akan diterapkan bersama mitra yaitu pemaparan tehnik perbanyakan tanaman sukun dan pelatihan/praktek perbanyakan anakan sukun dengan tehnik stek akar sehingga petani dapat melakukan perbanyakan tanaman secara mandiri melalui aktifitas sosialisasi, pelatihan pengambilan bibit/anakan, penyiapan media dan pemeliharaan hingga siap tanam dan Monitoring dan evaluasi kegiatan perbanyakan tanaman sukun siap tanam. Hasilnya masyarakat dapat melakukan perbanyakan tanaman sukun melalui stek akar dan zat perangsang akar root up serta media tumbuh campuran pasir dan komposKata kunci; Artocarpus altilis, Kebun pendidikan, Pengabdian masyarakat, Stek akar
PEMANFAATAN MEDIA SOSIAL SEBAGAI KOMUNIKASI PEMASARAN BRAND ALFATEEMA DALAM PERSPEKTIF UU ITE
Authors: Kurnia Renita , Prasetyo Bahariandi Aji , Uma Dewi 
Published: July 2024

Media sosial telah mengubah cara penggunanya berkomunikasi, berinteraksi, dan berpartisipasi dalam kehidupan sosial dan budaya. Media sosial juga digunakan untuk berbisnis bagi masyarakat Indonesia. Pemanfaatan media sosial juga digunakan pebisnis dan perusahaan sebagai komunikasi pemasaran yang ditujukan kepada target sasarannya. Penerapan UU ITE sangat perlu ditegakkan agar pengguna media sosial tidak melakukan kesalahan yang dapat melanggar peraturan yang berlaku di Indonesia pada media sosial yang mereka miliki. Brand Alfeteema memanfaatkan memanfaatkan media sosialnya sebagai komunikasi pemasaran dalam memasarkan produknya hingga ke Malaysia dan Brunei Darussalam mengikuti aturan yang berlaku di Indonesia. Tujuan penelitian ini untuk mengetahui pemanfaatan media sosial sebagai komunikasi pemasaran brand Alfateema dalam perspektif UU ITE. Metode penelitian yang digunakan deksriptif kualitatif dengan pengumpulan data secara observasi, wawancara, dan dokumen. Brand Alfateema menggunakan media sosialnya untuk kegiatan komunikasi pemasaran seperti iklan, penjualan pribadi, promosi penjualan, public relations dan pemasaran langsung. Brand Alfateema melakukan komunikasi pemasaran dengan memanfaatkan media sosialnya menerapkan dengan baik Undang-Undang Nomor 11 Tahun 2008 Tentang Informasi dan Transaksi Elektronik Pasal 4, Pasal 9, Pasal 17 ayat 1-3, Pasal 28 ayat 1-2, dan Pasal 29dan Undang-Undang Nomor 19 Tahun 2016 Tentang Perubahan Atas Undang-Undang Nomor 11 Tahun 2008 Tentang Informasi dan Transaksi Elektronik Pasal 26 ayat 1.
DNA aptamer-functionalized PDA nanoparticles: from colloidal chemistry to biosensor applications
Authors: Zaw Ohnmar , Noon Shean Aye Nang , Daduang Jureerut , Proungvitaya Siriporn , Wongwattanakul Molin , Ngernyuang Nipaporn , Daduang Sakda , Shinsuphan Nikorn , Phatthanakun Rungrueang , Jearanaikoon Nichada , Maraming Pornsuda 
Published: July 2024

Polydopamine nanoparticles (PDA NPs) are widely utilized in the field of biomedical science for surface functionalization because of their unique characteristics, such as simple and low-cost preparation methods, good adhesive properties, and ability to incorporate amine and oxygen-rich chemical groups. However, challenges in the application of PDA NPs as surface coatings on electrode surfaces and in conjugation with biomolecules for electrochemical sensors still exist. In this work, we aimed to develop an electrochemical interface based on PDA NPs conjugated with a DNA aptamer for the detection of glycated albumin (GA) and to study DNA aptamers on the surfaces of PDA NPs to understand the aptamer-PDA surface interactions using molecular dynamics (MD) simulation. PDA NPs were synthesized by the oxidation of dopamine in Tris buffer at pH 10.5, conjugated with DNA aptamers specific to GA at different concentrations (0.05, 0.5, and 5 μM), and deposited on screen-printed carbon electrodes (SPCEs). The charge transfer resistance of the PDA NP-coated SPCEs decreased, indicating that the PDA NP composite is a conductive bioorganic material. Transmission electron microscopy (TEM) and scanning electron microscopy (SEM) confirmed that the PDA NPs were spherical, and dynamic light scattering (DLS), Fourier transform infrared spectroscopy (FTIR), and Raman spectroscopy data indicated the successful conjugation of the aptamers on the PDA NPs. The as-prepared electrochemical interface was employed for the detection of GA. The detection limit was 0.17 μg/mL. For MD simulation, anti-GA aptamer through the 5′terminal end in a single-stranded DNA-aptamer structure and NH2 linker showed a stable structure with its axis perpendicular to the PDA surface. These findings provide insights into improved biosensor design and have demonstrated the potential for employing electrochemical PDA NP interfaces in point-of-care applications.
Pharmacophore-based virtual screening of commercial databases against β-secretase 1 for drug development against Alzheimer’s disease
Authors: Han Xu , Guo Kaibo 
Published: July 2024

β-secretase 1, one of the most important proteins, is an aspartate protease. This membrane-associated protein is used for treating Alzheimer’s disease (AD). Several inhibitors have been pursued against β-secretase 1, but they still have not resulted effectively. Virtual screening based on pharmacophores has been shown to be useful for lead optimization and hit identification in the preliminary phase of developing a new drug. Here, we screen the commercially available databases to find the hits against β-secretase 1 for drug discovery against AD. Virtual screening for 200,000 compounds was done using the database from the Vitas-M Laboratory. The phase screen score was utilized to assess the screened hits. Molecular docking was performed on compounds with phase scores &gt;1.9. According to the study, the 66H ligand of the crystal structure has the maximum performance against β-secretase 1. The redocking of the co-crystal ligand showed that the docked ligand was seamlessly united with the crystal structure. The reference complex had three hydrogen bonds with Asp93, Asp289, and Gly291; one van der Waals interaction with Gly74; and three hydrophobic interactions. After equilibration, the RMSD of the reference compound sustained a value of ∼1.5 Å until 30 ns and then boosted to 2.5 Å. On comparison, the RMSD of the S1 complex steadily increased to ∼2.5 Å at 15 ns, displayed slight aberrations at approximately ∼2.5–3 Å until 80 ns, and then achieved steadiness toward the end of the simulation. The arrangements of proteins stayed condensed during the mockup when bonded to these complexes as stable Rg values showed. Furthermore, the MM/GBSA technique was employed to analyze both compounds’ total binding free energies (ΔGtotal). Our research study provides a new understanding of using 66H as anti-β-secretase 1 for drug development against AD.
Assessment of Bacillus species capacity to protect Nile tilapia from A. hydrophila infection and improve growth performance
Authors: Macias Leslye , Mercado Víctor , Olmos Jorge 
Published: July 2024

The present study evaluated the capacity of three Bacillus species to improve health status and growth performance of Nile Tilapia fed with high levels of soybean meal and challenged with Aeromonas hydrophila. In vitro experiments showed that β-hemolysin and metalloprotease enzymes were produced by A. hydrophila throughout the exponential growth phase. In vivo experiments showed that 107 colony-forming units (CFUs)/ml of this pathogen killed 50% of control group fishes in 13 days. To evaluate the influence of Bacillus strains on health status and growth performance in Nile Tilapia, 180 fishes (33.44 + 0.05 g) were distributed in 12 tanks of 200 L each, and animals were fed twice per day until satiety. 1) Control group without Bacillus, 2) Bacillus sp1, 3) Bacillus sp2, and 4) Bacillus sp3 groups were formulated containing 106 CFU/g. After 40 days of feeding, the fishes were intraperitoneally injected with 1 ml of A. hydrophila at 2 × 107 CFU/ml, and mortality was recorded. The results showed that cumulative mortality rate was significantly (p&lt; 0.05) lower in the Bacillus sp1 (25%), sp2 (5%), and sp3 (15%) groups, than the control group (50%). Weight gain was also significantly better (p&lt; 0.05) in the Bacillus sp1 (36%), sp2 (67%), and sp3 (55%) groups with respect to the control group (30%). In conclusion, functional diet formulated with high levels of soybean meal and supplemented with Bacillus sp2 could be an alternative to protect Nile tilapia cultures from A. hydrophila infections and improve fish growth performance.
Trends and findings of lipoprotein(a) testing and associated cardiovascular disease profiles: a large single-center study from the Middle East-Gulf region
Authors: Manla Yosef , AbdelWareth Laila , Shantouf Ronney , Aljabery Yazan , St John Terrence Lee , Sabbour Hani , Piechowski-Jozwiak Bartlomiej , Almahmeed Wael 
Published: July 2024

BackgroundLipoprotein(a) [Lp(a)] is a genetically determined risk factor for atherosclerotic cardiovascular disease (CVD). Limited data are available on Lp(a) testing from the Middle-East region. Therefore, we aim to evaluate the utilization and yield of Lp(a) testing over time and characterize CVD profiles of patients with abnormal Lp(a) tasting at a single-quaternary-care center in the United Arab Emirates.MethodsUnique Lp(a) tests conducted between 07/2017 and 10-2023 were included. Overtime trends in Lp(a) test utilization and abnormal Lp(a) [defined as Lp(a) &gt; 125 nmol/L] test findings were described. CVD rates in patients with abnormal Lp(a) were compared to those with Lp(a) ≤ 125 nmol/L using appropriate methods.ResultsIn our center, 0.95% of the patients (n = 5,677) had their Lp(a) measured, with a median level of 32 [11–82] nmol/L. Lp(a) was abnormal in 15.9% of the tests. Over the years 2018–2022, there was a 109% increase in Lp(a) testing, with concomitant up-trends in findings of abnormal Lp(a) (11.8% to 16.4%, P = 0.02). Compared to patients with Lp(a) ≤ 125 nmol/I, those with abnormal Lp(a) had higher rates of any prevalent CVD (34% vs. 25.1%, P &lt; 0.001), CAD (25.6% vs. 17.7%, P &lt; 0.001), HF (6.5% vs. 3.8%, P &lt; 0.001), and stroke (7.1% vs. 4.4%, P &lt; 0.001).ConclusionAlmost one in six patients tested for Lp(a) had abnormally elevated Lp(a), and CVD was prevalent in one-third of the patients who tested abnormal for Lp(a). The study highlights the growing awareness of the relevance of Lp(a) for CVD risk stratification and prevention.
Understanding the complex interplay of victimization experiences, empathy and school climate in Tunisian schools
Authors: Chokri Imed , Jarraya Mohamed 
Published: July 2024

AimOur study aims to examine the interactions between empathy, victimization, and the school climate in Tunisian primary schools.MethodIn total, 312 school children (158 boys and 154 girls), with a mean age of 10.75 ± 1.32 years old participated voluntarily in the study. The students answered three scales that measure the School Climate, the Victimization, and the Empathy.ResultThe results indicate a predominantly positive perception of the school climate by the students, both for the overall score (2.67 ± 0.64) and the scores of the different components of the school climate (ranging from 2.61 to 2.86). Also, girls seemed to have a more positive perception of the overall school climate, displaying higher scores (2.86 ± 0.54) compared to boys' scores (2.45 ± 0.67). Moreover, other results showed positive and statistically significant correlations (p &lt; 0.01) between the different dimensions of the school climate.ConclusionThe findings highlight the importance of creating a safe and inclusive school environment where empathy is encouraged, and effective measures are in place to prevent and address victimization.
Identification of disulfidptosis- and ferroptosis-related transcripts in periodontitis by bioinformatics analysis and experimental validation
Authors: Fu Yu , Xu Tingrui , Guo Mengru , Lv Wenhao , Ma Ning , Zhang Li 
Published: July 2024

BackgroundDisulfidptosis and ferroptosis are forms of programmed cell death that may be associated with the pathogenesis of periodontitis. Our study developed periodontitis-associated biomarkers combining disulfidptosis and ferroptosis, which provides a new perspective on the pathogenesis of periodontitis.MethodsFirstly, we obtained the periodontitis dataset from public databases and found disulfidptosis- and ferroptosis-related differentially expressed transcripts based on the disulfidptosis and ferroptosis transcript sets. After that, transcripts that are tissue biomarkers for periodontitis were found using three machine learning methods. We also generated transcript subclusters from two periodontitis microarray datasets: GSE16134 and GSE23586. Furthermore, three transcripts with the best classification efficiency were further screened. Their expression and classification efficacy were validated using qRT-PCR. Finally, periodontal clinical indicators of 32 clinical patients were collected, and the correlation between three transcripts above and periodontal clinical indicators was analyzed.ResultsWe identified six transcripts that are tissue biomarkers for periodontitis, the top three transcripts with the best classification, and delineated two expression patterns in periodontitis.ConclusionsOur study found that disulfidptosis and ferroptosis were associated with immune responses and may involve periodontitis genesis.