bluuebunny/crossref_metadata_2025_split huggingface dataset:
ANALISIS EFISIENSI SALURAN PEMASARAN KOMODITAS BROKOLI DI KELOMPOK TANI UTAMA DESA CIHERANG KECAMATAN PACET KABUPATEN CIANJUR
Authors: Nurulita Dinda , Malia Rosda , Nurkamil Yola 
Published: June 2024

Kubis merupakan komoditas hortikultura yang memiliki tingkat produksi tertinggi di Jawa Barat. Salah satu komoditas yang termasuk ke dalam komoditas kubis, yaitu brokoli. Brokoli mempunyai nilai jual tinggi, tepat jika pemasaran komoditas ini dikembangkan agar dapat memberikan keuntungan yang banyak bagi petani. Melalui penelitian ini diharapkan dapat mengidentifikasi saluran pemasaran komoditas brokoli di Kelompok Tani Utama dan mengetahui saluran pemasaran komoditas brokoli paling efisien di Kelompok Tani Utama. Penelitian ini dilaksanakan di Kelompok Tani Utama yang berlokasi di Desa Ciherang Kecamatan Pacet Kabupaten Cianjur dari bulan Januari – Juni 2022. Penelitian ini menggunakan Non-Probability sampling dengan teknik Snowball Sampling dalam penentuan responden. Hasil penelitian menunjukan bahwa : 1) Saluran pemasaran brokoli di Kelompok Tani Utama terdapat 4 saluran pemasaran, 2) saluran pemasaran brokoli yang paling efisien untuk petani adalah saluran pemasaran I dengan farmer’s share sebesar 69% dan saluran pemasaran brokoli paling efisien dan menguntungkan bagi pedagang besar adalah saluran pemasaran III dengan efisiensi saluran pemasaran sebesar 10%.
The Symbolic Meaning of the Banyan Plant in Hindu Rituals
Authors: Yuliana Euis Dewi , Wulaning Ayu Putu Desiana , Pradipta Gede Angga 
Published: June 2024

The philosophical meaning contained in each upakara plant is the most important thing that must be known and expressed again, so that Hindus have clear guidance and guidance in offering their yadnya. Without knowing clearly and definitely about the philosophical meaning contained in the upakara plant, it is suspected that over time there will be deviations in the implementation of Hindu religious rituals. Starting from the problem above, this study have question : (1) What is the form, classification and description of the banyan plant in Hindu religious rituals? (2) What are the uses/benefits of the banyan plant in Hindu religious rituals? (3) What is the mythology of the banyan plant used in Hindu religious rituals? (4) What is the philosophical meaning of the banyan plant used in Hindu religious rituals? Based on study, the following conclusions are drawn. (1) The use of plants as a means of ceremonial ceremonies will continue and be sustainable if the traditions that characterize Balinese society and culture are large traditions that are based on the implementation of various types of ceremonies, of which the yadnya ceremony is an important aspect of the Hindu religious belief system. (2) On the other hand, there is a point of view, if Balinese Hindus deepen their philosophy, then all types of ceremonies will fade or at least decrease, because their essence is known. Thus, it is suspected that the use of plants as ceremonial facilities will decrease as the implementation of various types of ceremonies fades or decreases. (3) Apart from the two views above, the use of plants, whether for carrying out ceremonies or to support the continuity of the cycles of the universe, provides a mandate to remind humans to protect plants of whatever type so that they do not experience degradation or even extinction. (4) Based on a literature search, not much has been revealed regarding the philosophical meaning of the upakara plant, and efforts in this direction need to be made.
Students’ Reading Comprehension of English Textual Literacy Among Zillenial Generation
Authors: Rahmawati Yeni , Khatimah Khusnul , Rachman Dzul , Sunarti Sunarti 
Published: June 2024

According to the Indonesian new curriculum which is generally called Kurikulum Merdeka reading comprehension of text becomes a fundamental skill of learning outcomes. However, a long time before the new curriculum was released reading skills, especially in learning a foreign language particularly English have always been the main thing. Starting from this condition, this study aimed to describe the students’ reading comprehension of English textual literacy among the Zillenial generation. Another goal, of this study, was to identify the students’ reasons related to their reading in textual comprehension. This study applied mixed methods both quantitative and qualitative. The design used descriptive statistics and interviews. the instrument used was a test and a list of interviews. the population in this study was 99 students of Public Vocational Schools in Samarinda whereby, overall, this population also became the sample. The result was the students in the fair category. The majority of students got a score around 70 which was included as a fair category. This is in line with the school policy of considering minimum passing grades in English subjects. From qualitative data, it was found that the students were helped by the test which was considered as lower-order thinking (LOT). The test was in multiple choice and the topic was familiar. Surprisingly, based on the findings, this Zillenial generation has low literacy as they acknowledged that they don’t have any specific time for doing English literacy except only the teacher’s command. If the topic of the text is considered difficult usually, they will use translator apps to comprehend the text easily.
Therapeutic potential of silver nanoparticles from Helianthemum lippii extract for mitigating cadmium-induced hepatotoxicity: liver function parameters, oxidative stress, and histopathology in wistar rats
Authors: Laib Ibtissam , Ali Boutlilis Djahra , Alsalme Ali , Croun David , Bechelany Mikhael , Barhoum Ahmed 
Published: June 2024

Introduction: This study explores the therapeutic potential of silver nanoparticles (Ag NPs) synthesized using a Helianthemum lippii extract in mitigating cadmium-induced hepatotoxicity in Wistar rats. Given the increasing environmental and health concerns associated with cadmium exposure, novel and eco-friendly therapeutic strategies are essential.Methods: Ag NPs were characterized using X-ray diffraction, UV-Vis spectrometry, and energy-dispersive X-ray spectroscopy with scanning electron microscopy, confirming their formation with a cubic crystal structure and particle sizes ranging from 4.81 to 12.84 nm. A sub-acute toxicity study of Ag NPs (2 mg/kg and 10 mg/kg) was conducted, showing no significant difference compared to untreated control rats (n = 3 animals/group). Subsequently, adult Wistar rats (n = 5/group) were divided into a control group and three experimental groups: Ag NPs alone, exposure to 50 mg/kg CdCl2 in drinking water for 35 days, and CdCl2 exposure followed by 0.1 mg/kg/day Ag NPs intraperitoneally for 15 days.Results: In the CdCl2-exposed group, there was a significant decrease in body weight and increases in alanine and aspartate transaminase levels (p &lt; 0.05 vs. control), indicating hepatotoxicity. Additionally, antioxidant defenses were decreased, and malondialdehyde levels were elevated. Liver histology revealed portal fibrosis, inflammation, necrosis, sinusoid and hepatic vein dilation, and cytoplasmic vacuolations. Treatment with Ag NPs post-CdCl2 exposure mitigated several adverse effects on liver function and architecture and improved body weight.Discussion: This study demonstrates the efficacy of Ag NPs synthesized via a green method in reducing cadmium-induced liver damage. These findings support the potential of Ag NPs in therapeutic applications and highlight the importance of sustainable and eco-friendly nanoparticle synthesis methods. By addressing both toxicity concerns and therapeutic efficacy, this research aligns with the growing emphasis on environmentally conscious practices in scientific research and healthcare.
Immuno-informatics study identifies conserved T cell epitopes in non-structural proteins of Bluetongue virus serotypes: formulation of a computationally optimized next-generation broad-spectrum multi-epitope vaccine
Authors: Kolla Harish Babu , Dutt Mansi , Kumar Anuj , Hebbandi Nanjunadappa Roopa , Karakach Tobias , Singh Karam Pal , Kelvin David , Clement Mertens Peter Paul , Umeshappa Channakeshava Sokke 
Published: July 2024

IntroductionBluetongue (BT) poses a significant threat to the livestock industry, affecting various animal species and resulting in substantial economic losses. The existence of numerous BT virus (BTV) serotypes has hindered control efforts, highlighting the need for broad-spectrum vaccines.MethodologyIn this study, we evaluated the conserved amino acid sequences within key non-structural (NS) proteins of BTV and identified numerous highly conserved murine- and bovine-specific MHC class I-restricted (MHC-I) CD8+ and MHC-II-restricted CD4+ epitopes. We then screened these conserved epitopes for antigenicity, allergenicity, toxicity, and solubility. Using these epitopes, we developed in silico-based broad-spectrum multiepitope vaccines with Toll-like receptor (TLR-4) agonists. The predicted proinflammatory cytokine response was assessed in silico using the C-IMMSIM server. Structural modeling and refinement were achieved using Robetta and GalaxyWEB servers. Finally, we assessed the stability of the docking complexes through extensive 100-nanosecond molecular dynamics simulations before considering the vaccines for codon optimization and in silico cloning.ResultsWe found many epitopes that meet these criteria within NS1 and NS2 proteins and developed in silico broad-spectrum vaccines. The immune simulation studies revealed that these vaccines induce high levels of IFN-γ and IL-2 in the vaccinated groups. Protein-protein docking analysis demonstrated promising epitopes with strong binding affinities to TLR-4. The docked complexes were stable, with minimal Root Mean Square Deviation and Root Mean Square Fluctuation values. Finally, the in silico-cloned plasmids have high % of GC content with &gt; 0.8 codon adaptation index, suggesting they are suitable for expressing the protein vaccines in prokaryotic system.DiscussionThese next-generation vaccine designs are promising and warrant further investigation in wet lab experiments to assess their immunogenicity, safety, and efficacy for practical application in livestock. Our findings offer a robust framework for developing a comprehensive, broad-spectrum vaccine, potentially revolutionizing BT control and prevention strategies in the livestock industry.
A novel in vitro cell model of the proteinase/antiproteinase balance observed in alpha-1 antitrypsin deficiency
Authors: Chen Celine H. , Crisford Helena , Scott Aaron , Sapey Elizabeth , Stockley Robert A. 
Published: July 2024

Background: Alpha-1 antitrypsin deficiency (AATD) is a genetic condition resulting from mutations in the alpha-1 antitrypsin (AAT) protein, a major systemic antiproteinase, resulting in reduced/no release of AAT, disrupting the proteinase/antiproteinase balance. A sustained imbalance can cause structural changes to the lung parenchyma, leading to emphysema. Predicting and assessing human responses to potential therapeutic candidates from preclinical animal studies have been challenging. Our aims were to develop a more physiologically relevant in vitro model of the proteinase/antiproteinase balance and assess whether the data generated could better predict the efficacy of pharmacological candidates to inform decisions on clinical trials, together with expected biomarker responses.Methods: We developed an in vitro model assessing the proteinase/antiproteinase balance by the changes in the fibrinogen cleavage products of neutrophil elastase (NE) and proteinase 3 (PR3). This allowed the assessment of physiological and pharmaceutical neutrophil serine proteinase (NSP) inhibitors to determine the putative threshold at which the maximal effect is achieved.Results: AAT significantly reduced NE and PR3 activity footprints, with the maximal reduction achieved at concentrations above 10 μM. The inhibitor MPH966 alone also significantly reduced NE footprint generation in a concentration-dependent manner, leveling out above 100 nM but had no effect on the PR3 footprint. At levels of AAT consistent with AATD, MPH966 had an additive effect, reducing the NE activity footprint more than either inhibitor alone.Conclusion: Our results support an inhibitor threshold above which the activity footprint generation appears resistant to increasing dosage. Our model can support the testing of inhibitors, confirming activity biomarkers as indicators of likely pharmaceutical efficacy, the assessment of NSP activity in the pathophysiology of emphysema, and the likely function of biological or pharmacological inhibitors in disease management.
The effect of escitalopram in treating mild to moderate depressive disorder and improving the quality of life in patients undergoing coronary artery bypass grafting – a double-blind randomized clinical trial
Authors: Baradaran Abdolvahab , Ardakani Mohammad Reza Khodaie , Bateni Fatemeh Sadat , Asadian-Koohestani Fatemeh , Vahedi Mohsen , Aein Afsaneh , Shahmansouri Nazila , Sadighi Gita 
Published: June 2024

IntroductionChronic depression and anxiety can be a risk factor for coronary aArtery bypass grafting (CABG) and is an emerging factor after coronary artery disease when the patient is admitted to the hospital and after surgery. We aimed to assess the effect of Escitalopram in treating mild to moderate depressive disorder and improving the quality of life in patients undergoing CABG.MethodsIn this randomized clinical trial, 50 patients undergoing CABG referred to Tehran Heart Hospital from January 2021 to May 2021 and were suffering from mild to moderate depression were randomly assigned to one of the two groups of Escitalopram or placebo. The level of depression was assessed based on Beck’s depression inventory and the quality-of-life status and its domains were assessed based on the SF-36 questionnaire in 2 groups. Measurements were obtained at baseline and at four and eight weeks after treatment. Chi-square, Fisher’s exact, paired, and Wilcoxon tests or ANOVA were used as appropriate.ResultsThere was no significant difference between the level of depression between the two study groups at baseline (P=0.312). There was no significant difference between the quality of life and its domains in the two study groups at baseline (P=0.607). However, the most important effect of Escitalopram was reducing depression scores in the intervention group at weeks 4 and 8 after treatment compared to the placebo group (P&lt;0.001). The quality of life and its domains were significantly higher in the Escitalopram group eight weeks after treatment (P=0.004). The amount of drug side effects at 2 and 4 weeks after treatment had no significant difference between the groups (P&gt;0.05).ConclusionEscitalopram was effective in treating mild to moderate depressive disorder and improving quality of life in patients undergoing CABG.Clinical trial registrationhttps://irct.behdasht.gov.ir/, identifier IRCT20140126016374N2.
FACTORS RELATED TO THE QUALITY OF HANDOVER OF SITUATION, BACKGROUND, ASSESSMENT, RECOMMENDATION (SBAR) METHODS ON INTERNAL PATIENT TRANSFER
Authors: Pujiyanto Tri Ismu , Wahyuningtyas Salvania Ermi , Dwi Kustriyanti  
Published: July 2024

Communication errors are one of the causes of patient safety incidents. Handover of internal patient transfers using the SBAR methodis a form of communication whose implementation has not been carried out optimally. Purpose: To determine the factors associatedwith the quality of the SBAR handover method in internal patient transfers. Research method: Type of correlational quantitativeresearch. Cross-sectional research design. The population consisted of 94 nurses who carried out internal patient transfers. Thesample consisted of 76 nurses who transferred level 0 patients. The sampling technique uses purposive sampling. Measuring toolsuse questionnaires and observation sheets. Statistical tests use the Chi-Square test. Results: Nurse attitude (P-value = 0.000) andOdds Ratio 8.543, receive motivation (P-value = 0.003) and Odds Ratio 5.315, Head of Space leadership (P-value = 0.001) and OddsRatio 6.367, and head of room supervision (P-value = 0.002) and Odds Ratio 5.769. has a P-value of <0.005, using Chi-Square Testanalysis and Logistic Regression to see the most influential variable, nurse attitude. Conclusion: The attitude sub-variable is the mostinfluential on the quality of SBAR method handover in internal patient transfer. Suggestion: Hospitals must conduct periodic andcontinuous evaluations of handover activities. The nurse's attitude that needs to be improved is the understanding of the sta ges andadjustment of the appropriate internal transfer time of the patient.
القيادة المدمرة ودورها في تنمية الرهاب لدى الافراد العاملين دراسة حالة لعيّنة من العاملين في معمل اسمنت الكوفة في محافظة النجف الأشرف
Authors: النصراوي حامد عادل 
Published: June 2024

المستخلص إن البحث الحالي يسعى إلى معرفة طبيعة العلاقة بين القيادة المدمرة والرهاب في معمل اسمنت الكوفة, اذ تتمثل أهميته في تناوله لمتغيرين حساسين جداً في بيئة الاعمال والأهم من ذلك هو حجم التحدي الذي واجهه الباحث في طرحه لمتغير القيادة المدمرة عند جمعه للبيانات، فضلاً عن وضع الأسس الصحيحة والمناسبة لمعالجة مشكلة واقعية تؤثر بصورة مباشرة على بيئة العمل في أحد أهم المؤسسات الصناعية العراقية ، لذا قام الباحث بإستخدام طريقة العينة العشوائية وتوزيع 168 استبانة على عدد من الموظفين والموظفات في المعمل المذكور. وكان عدد الاستبانات المسترجعة 148 إستبانة، أما الصالحة للتحليل الإحصائي فقد بلغ عددها (145) استبانة وبمعدل (87%) من الاستبانات المسترجعة، وتم تحليلها بوساطة البرنامج الإحصائي المتقدم AMOS v.20 فضلاً عن البرنامج الاحصائي SPSS v.18. وأظهرت النتائج النظرية وجود فجوة معرفية لتفسير طبيعة العلاقة بين القيادة المدمرة والرهاب في المنظمات بشكل عام وفي المعامل الصناعية بشكل خاص, كما أظهرت النتائج التطبيقية وجود تأثير معنوي وموجب للقيادة المدمرة في الرهاب.الكلمات الرئيسة: القيادة المدمرة، الرهاب ، معمل اسمنت الكوفة في محافظة النجف الاشرف.AbstractThe current research seeks to know the nature of the relationship between destructive leadership and phobia in the Kufa Cement Factory. It is important to deal with two variables that are very sensitive to the business environment and, more importantly, the size of the challenge facing the researcher in introducing the destructive variable of the data collection. As well as establishing the right and appropriate foundations to address a real problem that directly affects the work environment in one of the most importantIraqi industrial enterprises. Therefore, the researcher used random sample method and distributed 168 questionnaire to a number of employees and employees And female staff in the Factory.The number of questionnaires retrieved was 148, and Valid for statistical analysis (145) and 87% of the retrieved responses . It was analyzed by the AMOS v.20 Advanced Statistical Program as well as the Statistical Program SPSS v1.8.The theoretical results showed a knowledge gap to explain the nature of the relationship between destructive leadership and phobia in organizations in general and in industrial Factories in particular. The results showed that there is a significant and significant impact of destructive leadership in phobia.Key words: destructive leadership, phobia, Kufa Cement Factory in province of Najaf.
استكشاف و تحليل رضا الزبون الرقمي دراسة استطلاعية لآراء عينة من الزبائن المتسوقين عبر وسائل التواصل الاجتماعي
Authors: عبد الرسول حسين علي 
Published: June 2024

تسعى الدراسة الحالية إلى تحديد أهم العوامل المؤثرة على عملية التسوق عبر وسائل التواصل الاجتماعي تحديداً من خلال استكشاف و تحليل رضا الزبون الرقمي لسد الفجوة المعرفية من خلال دراسة وتحليل تجربة الشراء الرقمي. بالاعتماد على البيانات التي تم جمعها من استطلاع لعينة من زبائن المتسوقين عبر التجزئة الالكترونية بلغ عددهم (365) فرد. و حددت الدراسة بالاعتماد على الدراسات السابقة كل من (سهولة الاستخدام ، معلومات المنتج ، الايصائية ، الاستجابة للزبون ، سهولة الاسترجاع ) كعوامل مؤثرة ومحددة لرضا الزبون الرقمي ، في حين اعتبرت كل من (نية تكرار الشراء، كلمة الفم المنطوقة ، الرغبة بدفع المزيد) نتائج واثار رضا الزبون الرقمي عن التسوق و الشراء عبر وسائل التواصل الاجتماعي. تقدم الدراسة مساهمة فكرية و تطبيقية في مجال البيع بالتجزئة والتسوق الرقمي خلال تطوير واختبار نموذج جديد من محددات و آثار رضا الزبون الرقمي.
و اثبتت نتائج الدراسة على إن سهولة الإسترجاع و الاستجابة للزبائن من أهم المساهمين في رضا الزبون الرقمي. وكان لسهولة الاستخدام ، معلومات المنتج الايصائية ، جميعها لها تأثير ولكن بمستويات أقل . و تظهر النتائج التي توصلنا إليها أن رضا الزبون الرقمي يؤدي إلى تعزيز نية إعادة الشراء ، واحتمال تقديم توصيات إيجابية للآخرين عن طريق الفم المنطوقة، ولكن لم يظهر تأثير معنوي على رغبة الزبون بدفع المزيد.
الكلمات المفتاحية : رضا الزبون الرقمي ، الايصائية ، نية تكرار الشراء، كلمة الفم المنطوقة .
تحليل وقياس اثر المزاحمة في الاقتصاد العراقي للمدة (2004 – 2022)
Authors: السعداوي علياء ماجد دخيل , التميمي سامي عبيد محمد 
Published: June 2024

يهدف البحث الى توضيع دور القطاع الحكومي في الاقتصاد العراقي وتأثير هذا الدور على القطاع الخاص ، حيث يلعب القطاع الحكومي دوراً حاسماً في تطور الاقتصاد العراقي ، وأن زيادة الانفاق الحكومي من خلال أنشاء فرص عمل ، وتوفير دخل لهم ، وشراء المواد اللازمة لمشاريع البنى التحتية، كل ذلك يجعل للقطاع العام دور أيجابي في الاقتصاد العراقي من جهه ، ومن جهة أخرى إن التوسع في الانفاق الحكومي في ظل الظروف الأمنية والصحية وتقلبات اسعار النفط وضعف الأيرادات الضريبية ، قد يخلق ضغظاً كبيراً على موازنة الدولة، ويكون تأثير ذلك الضغط في خلق عجزاً مالياً في الميزانية العامة ، وبالتالي يصعب تمويل هذا التوسع في الانفاق الحكومي ، فقد تضطر الدولة الى تمويل العجز بواسطة الدين العام الداخلي والخارجي مما يزاحم القطاع الخاص على الأموال المتاحة للاقراض عن طريق ارتفاع سعر الفائدة ، واعتمدت الدراسة في قياس أثر المزاحمة الاقتصادية بين القطاع العام والقطاع الخاص على منهجية ARDR ، كما توصلت على الرغم من اتجاه الاستثمار الخاص نحو الارتفاع كقيم مطلقة او كنسبة من الناتج المحلي الاجمالي ، الا ان ذلك لا يمنع من مزاحمة الاستثمار العام للقطاع الخاص وخصوصا المزاحمة على الاموال المتاحة للاقتراض للقطاع الخاص ، وذلك عندما تلجأ الحكومة للاقتراض لتمويل الزيادة في الانفاق العام ، كذلك أن العلاقة بين الاستثمارات العامة والاستثمارات الخاصة تصبح تكاملية ،أي ان الاستثمارات العامة تحفز الاستثمارات الخاصة في الاجل الطويل .
الاندماج المصرفي واثرة في تحسين جودة الخدمات المصرفية :دراسة استطلاعية لاراء عينة من زبائن فروع مصرف الرشيد المندمجة في محافظة البصرة
Authors: عبادي عذراء جاسب 
Published: June 2024

تهدف هذه الدراسة الى التعرف على الاندماج المصرفي , واثرة في جودة الخدمات المصرفية بفروع مصرف الرشيد المندمجة في محافظة البصرة وذلك من خلال ابعاد جودة الخدمات المصرفية.
واعتمدت الباحثة المنهج الوصفي التحليلي ,مستخدما استمارة الاستبيان كاداة للجمع بيانات الدراسة ,وتشمل مجتمع الدراسة من جميع موظفين فروع مصرف الرشيد المندمجة في محافظة البصرة , وقد تم اختيار عينة عشوائية (80) موظف وزعت عليهم استبانة الدراسة واسترجع منها (60) استبانة صالحة للتحليل , أي بنسبة (75% ) من عينة الدراسة .
تم تحليل بيانات الدراسة واختبار فرضياتها من خلال تطبيق بعض أدوات التحليل الاحصائي الوصفي والاستدلالي الأكثر ملائمة لطبيعة تلك البيانات , وذلك باستخدام برنامج الحزمة الإحصائية للعلوم الاجتماعية والمعروف اختصارا (SPSS ) وبعد اجراء التحليلات الإحصائية المناسبة للبيانات توصلت الى وجود اثر ذو دلالة إحصائية عند مستوى ( 0.05≥α ) للاندماج المصرفي في جودة الخدمات المصرفية في فروع مصرف الرشيد المندمجة في محافظة البصرة , وجود علاقة ارتباط طردية قوية موجبة بين الاندماج المصرفي وجودة خدمات المصرفية ,واوصت الدراسة بزيادة الاهتمام بجودة الخدمات المصرفية وذلك من خلال تحسين ابعاد الجودة المتمثلة في (الملموسية ,الاعتمادية ,الاستجابة ,الأمان ,التعاطف ) ,وضرورة الاهتمام اكثر بالاندماج المصرفي باعتباره يؤثر بشكل كبير على تحسين جودة الخدمات المصرفية , وضرورة القيام بدورات تدريبية للموظفين للتعرف على اخر المستجدات في المجال الإداري والتنظيمي من اجل القيام بأداء الاعمال بكفاءة لماله انعكاس إيجابي على جودة الخدمات المصرفية .