bluuebunny/crossref_metadata_2025_split huggingface dataset:
Translanguaging as a Mediational Tool in the Process of Feedback in Second Language Writing
Authors: Li Danli , Wang Yibei 
Published: July 2024

Abstract
A growing number of studies have focused on pedagogical translanguaging, helping to develop students’ writing competence in second language (L2) classrooms. However, the role of translanguaging in the feedback from both teacher and students in L2 writing remains scant. Adopting a sociocultural approach, this study aims to investigate how translanguaging practices in L2 writing tutorials can mediate learning in the process of feedback, especially in the post-writing stage. Data were collected from classroom observations and writing assignments, with seven students and one tutor in 16-week writing tutorials at a university in Central China. Data were analyzed through thematic analysis and microgenetic analysis. Results show that teachers and students work together to construct knowledge and expand the multilingual repertoire and that translanguaging strategies promote feedback in the dialogic process. The mediating role of translanguaging in L2 writing tutorials can offer opportunities to enhance content learning, encourage learner participation, establish comprehension and provide pastoral care. The findings also shed light on L2 writing pedagogy that translanguaging as a mediational tool can decolonize curricula that are primarily English-medium and promote awareness of teachers in an equitable educational environment, by supporting equity for culturally and linguistically diverse students.
Preclinical antidiabetic and antioxidant effects of Erythrophleum africanum (benth.) harms in streptozotocin-induced diabetic nephropathy
Authors: Ojo Oluwafemi A. , Ajeigbe David , Ogunlakin Akingbolabo D. , Odesanmi Olalekan E. , Ayomipo Mojisola , Berana Godwin , Ayeni Peluola , Ajayi-Odoko Omolola A. , Ayokunle Damilare I. , Ojo Adebola B. , Ajiboye Basiru O. , Ojo Omolara O. , Dahunsi Samuel O. 
Published: July 2024

Abstract

Objectives
This study investigated the antidiabetic effects of the methanolic extract of E. africanum (MEEA) stem bark on streptozotocin (STZ)-induced diabetic nephropathy (DN) in Wistar rats.

Methods
The in vitro enzyme (α-amylase) inhibitory activity of MEEA was measured using a standard procedure. Diabetic rats with fasting blood glucose above 250 mg/dL were considered diabetic and were divided into the following groups: control (distilled water-treated), diabetic-control, diabetic metformin (100 mg/kg), diabetes + MEEA (150 mg/kg), and diabetes + MEEA (300 mg/kg) via oral gavage once daily for 14 days. At the end of the experimental period, kidney tissues were collected for biochemical and histological analyses. Kidney apoptosis and marker gene expression were measured by real-time quantitative PCR.

Results
MEEA exhibited α-amylase inhibitory effects. MEEA significantly (p<0.05) reduced the STZ-induced increases in blood glucose, serum urea, serum creatinine, uric acid, alanine aminotransferase, alkaline phosphatase, and malondialdehyde and increased the STZ-induced decreases in superoxide dismutase, catalase, and reduced glutathione. In addition, MEEA protects against DN by significantly downregulating the mRNA expression of cyclic adenosine monophosphate (cAMP), protein kinase A (PKA), cAMP-response binding protein (CREB), and cFOS and upregulating B-cell lymphoma 2 (Bcl-2), suggesting that the nephroprotective ability of MEEA is due to the modulation of the cAMP/PKA/CREB/cFOS signaling pathway. Furthermore, MEEA treatment protected against histopathological alterations observed in diabetic rats.

Conclusions
The data from this study suggest that MEEA modulates glucose homeostasis and inhibits redox imbalance in DN rats.
Effectiveness of whole exome sequencing analyses in the molecular diagnosis of osteogenesis imperfecta
Authors: Evin Ferda , Atik Tahir , Onay Huseyin , Goksen Damla , Darcan Sukran , Cogulu Ozgur , Ozen Samim 
Published: July 2024

Abstract

Objectives
Osteogenesis imperfecta (OI) is a group of phenotypically and genetically heterogeneous connective tissue disorders that share similar skeletal anomalies causing bone fragility and deformation. This study aimed to investigate the molecular genetic etiology and to determine the relationship between genotype and phenotype in OI patients with whole exome sequencing (WES).

Methods
Multiplex-Ligation dependent Probe Amplification (MLPA) analysis of COL1A1 and COL1A2 and WES were performed on cases between the ages of 0 and 18 whose genetic etiology could not be determined before using a targeted next-generation sequencing panel, including 13 genes (COL1A1, COL1A2, IFITM5, SERPINF1, CRTAP, P3H1, PPIB, SERPINH1, FKBP10, SP7, BMP1, MBTPS2, PLOD2) responsible for OI.

Results
Twelve patients (female/male: 4/8) from 10 different families were included in the study. In 6 (50 %) families, consanguineous marriage was noted. The clinical typing based on Sillence classification; 3 (25 %) patients were considered to be type I, 7 (58.3 %) type III, and 2 (16.7 %) type IV. Deletion/duplication wasn’t detected in the COL1A1 and COL1A2 genes in the MLPA analysis of the patients.
Twelve patients were molecularly analyzed by WES, and in 6 (50 %) of them, a disease-causing variant in three different genes (FKBP10, P3H1, and WNT1) was identified. Two (33.3 %) detected variants in all genes have not been previously reported in the literature and were considered deleterious based on prediction tools. In 6 cases, no variants were detected in disease-causing genes.

Conclusions
This study demonstrates rare OI types’ clinical and molecular features; genetic etiology was determined in 6 (50 %) 12 patients with the WES analysis. In addition, two variants in OI genes have been identified, contributing to the literature.
Ecological discourse analysis and meaning interpretation of BBC news reports on 2019 Australian bushfires from the perspective of transitivity system
Authors: Li Meijing , Liu Zhencong 
Published: July 2024

Abstract
The unprecedented 2019/20 Australian bushfires prompted this paper to conduct a transitivity analysis on the top three processes (material, relational, and verbal) in selected BBC news reports. Guided by the ecological philosophical view of “harmony with diversity, interaction, and coexistence,” the research aims to interpret ecological meanings in the text and enhance people’s awareness of environment conservation. The findings reveal that these news reports predominantly utilized material and relational processes to depict the devastating impact of the Australian bushfires on wildlife, the efforts of firefighters, volunteer rescue missions for wildlife, and the roles of individuals involved. These reports also conveyed extensive ecological information, highlighting the ecological crisis arising from the fires, the threat to species diversity, and the active social responsibility of various stakeholders. This research contributes to a deeper understanding of the ecological implications of the Australian bushfires and encourages proactive ecological protection measures.
Thermodynamic characteristics and aggregation behavior of surface active ionic liquids in presence of vitamin B7 (biotin)
Authors: Sharma Pooja , Sharma Shubham , Budhalakoti Bharti , Kumar Harsh 
Published: July 2024

Abstract
This study investigated the influence of vitamin B7 (biotin) at different concentrations (0.1, 0.3 and 0.5) mM on the micellisation behaviour of three different ionic liquids with different cationic headgroups, namely N-methylmorpholinium bromide [Mor1,12][Br], N-dodecyl-N-methylpyrrolidinium bromide [Pyrr1,12][Br], and 1-dodecyl-3-methylimidazolium bromide [C12mim][Br], at four different temperatures (298.15, 303.15, 308.15, and 313.15) K using electrical conductivity and surface tension measurements. The evaluated CMC values for the studied system were used to obtain information about the colloidal behavior of the ionic liquids in the presence of biotin. The different thermodynamic parameters were studied. Tensiometry was used to determine the interfacial properties. The parameters obtained were used to study the different types of interactions for micelle formation. The main objective of studying these interactions is to further utilize this type of mixture in pharmaceutical industry, medicinal chemistry, and bio industry.
Robustanic acid as a glutaminase and Na+, K+-ATPase inhibitor from leaves of Eucalyptus globulus
Authors: Shimada Atsumi , Ueno Hiroshi , Kawabata Kohei , Inagaki Masanori 
Published: July 2024

Abstract
This study was to compare glutaminase and Na+, K+-ATPase inhibitory activities of 20 herbal extracts and investigate the isolation, structural elucidation and those inhibitory activities of three triterpenes from the selected extract of Eucalyptus globulus Labill. Three triterpenes, ursolic acid (1), robustanic acid (2) and ursolic acid lactone (3), were identified by analyzing their NMR and MS spectral data and comparison of these with reported data. The IC50 values of 1–3 and the control compound against glutaminase, 6-diazo-5-oxo-l-norleucine (DON), were 443 μM, 334 μM, 963 μM and 134 μM, respectively. The IC50 values of 1, 2 and the control compound against Na+, K+-ATPase and ouabain, were 180 μM, 56 μM and 0.5 μM, respectively. Compounds 1 and 2 may serve as potential lead compounds for the prevention and treatment of neurodegenerative and lifestyle-related diseases by targeting glutaminase and Na+, K+-ATPase. This is the first report on glutaminase and Na+, K+-ATPase inhibitory activities of 2.
Education Unit’s Characteristics and Covid-19 Positivity Rate in Yogyakarta : Ecological Study
Authors: Nathaniela Regina Marsha , Ningrum Dina Nur Anggraini , Sutarjo Puji 
Published: July 2024

Abstract
Limited Face-to-Face Learning (PTM Terbatas) during COVID-19 pandemic allowed interaction between populations which led to COVID-19 transmission in schools. Factors affecting the COVID-19 transmission in schools need to be known to minimize the wider spread of cases. This study aims to examine the relationship between education unit’s characteristics such as school location, educational level, school status, number of PTM participants, and health protocols implementation, to the COVID-19 positivity rate in education units in Daerah Istimewa Yogyakarta. The research design is cross-sectional ecological study with education unit as the unit analysis. Sample of 292 education units sourced from secondary data of PTM Terbatas Surveillance was analyzed univariately and bivariately with Chi-Square test. Results showed health protocols implementation (p=0.022; PR=1.657; 95% CI=1.128-2.435) had a significant relationship to the COVID-19 positivity rate. School location, educational level, school status, and the number of PTM participants had no significant relationship to the COVID-19 positivity rate. Schools with any characteristics need to encourage school communities to keep implementing health protocols to prevent COVID-19 transmission in schools.

Abstrak
Pembelajaran Tatap Muka (PTM) Terbatas saat pandemi COVID-19 memungkinkan terjadinya interaksi antar populasi yang menyebabkan terjadinya penularan COVID-19 di sekolah. Faktor yang mempengaruhi penularan COVID-19 di sekolah perlu diketahui untuk meminimalisir penyebaran kasus yang lebih luas. Penelitian ini bertujuan untuk menguji hubungan antara karakteristik satuan pendidikan seperti lokasi sekolah, jenjang pendidikan, status sekolah, jumlah peserta PTM, dan penerapan protokol kesehatan, terhadap positivity rate testing tracing COVID-19 pada satuan pendidikan di Daerah Istimewa Yogyakarta. Desain penelitian ini adalah cross-sectional studi ekologi dengan satuan pendidikan sebagai unit analisis. Sampel sebanyak 292 satuan pendidikan bersumber dari data sekunder Surveilans PTM Terbatas dianalisis secara univariat dan bivariat dengan uji Chi-Square. Hasil penelitian menunjukkan penerapan protokol kesehatan (p=0,022; PR=1,657; 95%CI=1,128-2,435) memiliki hubungan yang signifikan terhadap positivity rate COVID-19. Lokasi sekolah, jenjang pendidikan, status sekolah, dan jumlah peserta PTM tidak memiliki hubungan yang signifikan dengan positivity rate COVID-19. Sekolah dengan karakteristik apapun perlu mendorong warga sekolah untuk tetap menerapkan protokol kesehatan guna mencegah penularan COVID-19 di sekolah.
Spiritual care and spirituality in academic nursing training: scoping review
Authors: Costa Marília Lopes , Araújo Jéssica Naiara de Medeiros , Araújo Analice Campelo de , Dantas Ana Clara , Pérez Paloma Echevarría , Vitor Allyne Fortes 
Published: July 2024

Objective: To map existing studies in scientific literature addressing spiritual care and spirituality in academic nursing training.
Materials and method: This is a scoping review, whose article search was conducted in July 2023 in the databases Scopus, Medline/PubMed, ScienceDirect, Google® Scholar, and through a manual search of entries in the list of references of selected papers. The following research question was formulated for this study: How are spiritual care and spirituality addressed in academic nursingtraining? After applying the inclusion and exclusion criteria, the final sample consisted of 45 papers.
Results: The main findings highlight a deficit in academic training, the importance of teachers as facilitators of the teaching-learning process, the essential methodologies to address the issue of spirituality, and the specific competences required in spiritual care, such ascommunication, empathy, attitude towards the patient’s spirituality, personal support, counseling, and the proper application of the nursing process in this type of care.
Conclusions: This review made it possible to identify how spiritual care and spirituality are addressed in the academic training of nurses, where the insertion of educational resources for spiritual care and approaches based on competences were emphasized. Despite this, spiritual-related teaching is still deficient in academic formation.Studies recommend modifying the curriculum to strengthen competencies related to spirituality and spiritual care in the nursing academy.
Capacidad de afrontamiento y adaptación de cuidadores familiares de personas con Parkinson
Authors: Barón Castro Mónica Margarita , Muñoz Astudillo María Nelcy , Cardona Toro José Gerardo 
Published: July 2024

Introducción: la enfermedad de Parkinson (EP) es un trastorno neurovegetativo frecuente que compromete la funcionalidad motora y genera dependencia progresiva para las actividades diarias. Objetivo: identificar la capacidad de afrontamiento y adaptación al rol de cuidadores familiares de personas con EP. Materiales y métodos: estudio descriptivo cuantitativo transversal con una muestra representativa de 50 cuidadores familiares de personas con EP. Se aplicó una encuesta telefónica con variables de caracterización sociodemográfica y la escala de capacidad de afrontamiento y adaptación de Callista Roy. Resultados: predominaron las mujeres cuidadoras (78 %), el grupo entre 50-59 años (38 %) y la formación universitaria (46 %). Los participantes, de manera general, mostraron capacidad de afrontamiento media con adaptación compensatoria (58 %), seguida de capacidad de afrontamiento alta con adaptación integrada (36 %). Los factores de afrontamiento más comprometidos fueron F2: reacciones físicas y enfocadas y F5: conocer y relacionar. Conclusiones: los cuidadores familiares de personas con EP registraron buena capacidad de afrontamiento y adaptación. Sin embargo, esta puede ser mejorada por medio del fortalecimiento de la educación sobre la enfermedad y la habilidad para responder a estímulos focales inmediatos. Con el fin de promover la adaptación, se sugiere conocer y comprender que el binomio “cuidador familiar-persona con EP” se constituye como un sistema adaptativo en interacción simbiótica con su entorno.
Identification of the active faults and seismotectonic zonation of Laos territory
Authors: Duong Thi N. , Huang B. S. , Dinh Van T. , Lai H. P. , Bui V. T. , Sulinthone O. , Pham H. T. , Pham N. D. , Nguyen V. H. , Duangpaseuth S. 
Published: July 2024

In this study, the main active faults in the territory of Laos were identified by analyzing the spatial relationship between the distributions of neo-tectonic faults and earthquake epicenters. The map of neo-tectonic faults was built by integrating the results of neo-tectonic faults research using geological-geomorphological data together with the lineament map obtained from remote sensing analysis. Nontectonic lineaments were eliminated by correlating the spatial distribution of the lineament field with a topographic map, DEM, and geological-geomorphological data. The earthquake data, including 4416 events in Laos and its surroundings, were collected from different sources: the International Seismological Center (ISC), the earthquakes recorded by the local seismic network in Laos, the seismic data in Vietnam, and the earthquake catalog provided by the Thailand Meteorological Department (TMD). Among these, 820 events were located using the hypocenter method, and the local network recorded the data. The magnitude conversion was applied to get a unified scale Mw. The catalog of 1617 main shocks obtained after eliminating foreshocks and aftershocks using the declustering technique was used for a spatial correlation with the neotectonic fault distribution to identify active faults. A total of 14 main active fault zones in the Laos territory were defined. Most are also seismogenic faults with Mw ≥ 5.0 occurring along their trace. Considering the characteristics of seismic activity and the active and neotectonic faults, the territory of Laos can be divided into six seismotectonic zones according to the decreasing level of seismic activity: the Western, the Northeastern Samnua, the Phongsali, the South Truong Son, the North Truong Son, and the Khorat zones. Each zone is characterized by relative homogeneity in the seismic activity and the characteristics of active and neotectonic faults.
Experience of accelerated ponseti method as a more convenient technique for newly diagnosed CTEV cases
Authors: Saha Somesh , Das Chinmoy , Dutta Swapnaneel 
Published: July 2024

The study's primary objective is to assess the effectiveness of this accelerated approach in achieving successful early correction of clubfoot deformity and improving the overall quality of life for these patients This is a prospective based hospital study where 50 patients (70 foot) taken into consideration. 50 patients randomised in two groups .one of which treated with conventional ponseti casting and other with accelerated ponseti casting. The mean days of plaster duration in accelerated casting group was 19.25 days as compared to 45.25 days in standard casting group (statistically significant, p&#60;0.001). Also, Pirani score at the end of last follow up was comparable in both the groups. Tenotomy rate was slightly higher in accelerated casting group (88%) as compared to standard group (80%) which may be attributed to higher initial Pirani score in former (5.5) as compared to later (5.0). Clubfoot is socially stigmatized in underdeveloped nations; the early and optimistic outcome of the accelerated Ponseti casting procedure has a profound effect on parents as well as the orthopaedic surgeon treating them. The total length of the Ponseti casting treatment has been significantly shortened by the accelerated method without any complications.
Fenomena Penggunaan Cadar di Kalangan Pemudi Muslimah Banjarmasin: Identitas Sosial di Tengah Arus Tren Mode Berpakaian
Authors: Abdillah Muhammad Torieq , Rahmattika Nadia 
Published: July 2024

The phenomenon of using the veil among Muslim youth Banjarmasin has pretty much been found since 2016. This study aims to determine the reasons and motivations, as well as the meaning of hijrah and fashion trends in dress, to participate in affecting young Muslim Banjarmasin in using the veil. The research method used is descriptive qualitative with field studies. The results of this study indicate that the reasons and motivations are based on a strong desire from oneself and the influence of a supportive environment and also because there is a figure who is used as a role model. Then, there are different meanings in mentioning whether to use the veil can be said to emigrate with opinions that are equally strong between mentioning part of the hijrah and not. Finally, wearing a face veil is not a fashion trend because wearing a face veil is part of the shari’a, as the opinion of the Shafi’i school. Fenomena menggunakan cadar di kalangan pemudi muslimah Banjarmasin cukup banyak ditemukan sejak 2016. Penelitian ini bertujuan untuk mengetahui alasan dan motivasi serta makna hijrah dan tren mode berpakaian turut serta mempengaruhi pemuda muslimah Banjarmasin dalam menggunakan cadar. Metode penelitian yang digunakan ialah kualitatif deskriptif dengan studi lapangan. Hasil penelitian ini menunjukkan bahwa alasan dan motivasi didasari oleh keinginan kuat dari diri sendiri serta adanya pengaruh lingkungan yang mendukung dan juga karena ada sosok yang dijadikan panutan. Lalu, adanya pemaknaan yang berbeda-beda dalam menyebutkan apakah menggunakan cadar dapat dikatakan berhijrah dengan pendapat yang sama-sama kuat antara menyebutkan bagian dari hijrah dan bukan. Terakhir, menggunakan cadar bukan termasuk tren mode berpakaian karena menggunakan cadar bagian dari syariat sebagaimana pendapat dari mazhab Syafi’i.
A double-masked, sham-controlled trial of rose bengal photodynamic therapy for the treatment of fungal and acanthameoba keratitis: Rose Bengal Electromagnetic Activation with Green Light for Infection Reduction (REAGIR) Study
Authors: Prajna Venkatesh , Prajna Lalitha , Sharma Sankalp , de Freitas Denise , Höfling-Lima Ana Luisa , Varnado Nicole , Abdelrahman Sarah , Cavallino Victoria , Arnold Ben , Lietman Tom , Rose-Nussbaumer Jennifer 
Published: July 2024

Abstract

Background: Infectious keratitis secondary to fungus or acanthamoeba often has a poor outcome despite receiving the best available medical therapy. In vitro Rose Bengal Photodynamic therapy (RB-PDT) appears to be effective against fungal and acanthamoeba isolates.22,23 In one published series RB-PDT reduced the need for therapeutic penetrating keratoplasty in severe bacterial, fungal, and acanthameoba keratitis not responsive to medical therapy.
Methods: This international, randomized, sham and placebo controlled 2-arm clinical trial, randomizes patients with smear positive fungal and acanthameoba and smear negative corneal ulcers in a 1:1 fashion to one of two treatment arms: 1) Topical antimicrobial plus sham RB-PDT or 2) Topical antimicrobial plus RB-PDT
Discussion: We anticipate that RB-PDT will improve best spectacle corrected visual acuity and also reduce complications such as corneal perforation and the need for therapeutic penetrating keratoplasty. This study will comply with the NIH Data Sharing Policy and Policy on the Dissemination of NIH-Funded Clinical Trial Information and the Clinical Trials Registration and Results Information Submission rule. Our results will be disseminated via clinicaltrials.gov website, meetings, and journal publications. Our data will also be available upon reasonable request.
Trial Registration: NCT, NCT05110001, Registered November 5, 2021.
https://www.clinicaltrials.gov/study/NCT05110001