bluuebunny/crossref_metadata_2025_split huggingface dataset:
Potential for Improving Therapy and Defining New Research Targets in Eosinophilic Oesophagitis Based on Understanding of Immunopathogenesis
Authors: Murch Simon H. , Allen Katrina , Chong Sonny , Dias Jorge Amil , Papadopoulou Alexandra ,   Eosinophilic Oesophagitis Working Group of ESPGHAN
Published: July 2013

ABSTRACTObjectives:This review considers the potential for therapeutic advances in the management of eosinophilic oesophagitis (EoE) based on recently increased understanding of the pathophysiology of the disorder.Methods:This is a review of publications characterising mucosal changes and leucocyte recruitment patterns in human and experimental EoE.Results:EoE, although diagnosed by epithelial infiltration of eosinophils, is actually a transmural inflammation in which eosinophil recruitment occurs via the deeper layers. Penetration of eosinophils into the epithelium is variable, explaining the need for multiple biopsies to diagnose what may be a clearly visible disorder. Fibrosis and neuromuscular dysfunction both occur within the subepithelial tissues. Recent murine studies have identified that T‐cell recruitment underpins antigen‐specific oesophageal eosinophil recruitment. Involvement of innate immunity is also suggested by the role of invariant natural killer T cells in experimental EoE.Conclusions:Looking beyond present therapeutic options with a view to future studies, we identify T cells as candidates for “upstream therapy” if antigen specificity or homing markers are determined. Evidence of aeroallergen sensitisation suggests the possibility of lymphocyte priming within nasal‐associated lymphoid tissue or Waldeyer ring, with the potential for topical therapy. We consider acquired neuromuscular dysfunction as a therapeutic target in acute symptomatic deterioration or bolus obstruction. We assess possible similarities with therapeutic stratagems for chronic asthma, recognising at the same time the anatomic specificity of the oesophagus and the difficulty in delivering effective topical medication to subepithelial tissues in this location compared with the airway.
catena-Poly[bis(μ-2,2′-bipyridin-6-olato)-κ3N,N′:O;O:N,N′-dicopper(I,II) [[tetrafluoridoniobium(V)]-μ-oxido]]
Authors: Zhong Zhi-Guo , Feng Yu-Quan , Zhang Ping 
Published: July 2013

A novel copper–niobium oxyfluoride, {[Cu2(C10H7N2O)2][NbOF4]}n, has been synthesized by a hydrothermal method and characterized by elemental analysis, EDS, IR, XPS and single-crystal X-ray diffraction. The structural unit consists of oneC2-symmetric [NbOF4]−anion and one centrosymmetric coordinated [Cu2(obpy)2]+cation (obpy is 2,2′-bipyridin-6-olate). In the [NbOF4]−anion, each NbVmetal centre is five-coordinated by four F atoms and one O atom in the first coordination shell, forming a square-pyramidal coordination geometry. These square pyramids are then further connected to each othervia transO atoms [Nb—O = 2.187 (3) Å], forming an infinite linear {[NbOF4]−}npolyanion. In the coordinated [Cu2(obpy)2]+cation, the oxidation state of each Cu site is disordered, which is confirmed by the XPS results. The disordered Cu sites are coordinated by two N atoms and one O atom from two different obpy ligands. The [NbOF4]−and [Cu2(obpy)2]+units are assembledviaweak C—H...F hydrogen bonds, resulting in the formation of a three-dimensional supramolecular structure. π–π stacking interactions between the pyridine rings [centroid–centroid distance = 3.610 (2) Å] may further stabilize the crystal structure.
Indoor autonomous flight of ornithopter using motion capture system
Authors: Kim Ho‐Young , Lee Jun‐Seong , Han Jae‐Hung 
Published: July 2013

PurposeThe purpose of this paper is to perform an indoor autonomous flight of ornithopter using a novel motion capture system.Design/methodology/approachThe ornithopter platform has no on‐board sensors and processors for state estimation or feedback control. Instead, passive markers on the ornithopter body reflect IR light of the multiple strobing CCD cameras, and the position data of the markers are streamed to the ground station in almost real time. Control inputs such as wingbeat frequency and rudder angle are generated by the proportional feedback controllers which are implemented in the ground station and transmitted to the ornithopter. Due to the complexity and nonlinearity of aerodynamics and flexible multibody dynamics, the flight dynamics of ornithopter are difficult to realize in the closed form of state‐space system equations. A controller for stabilizing the flight state variables of ornithopter is not necessary to be implemented by means of flapping counter‐forces and torques which make ornithopter have inherent flight stability. The gains of controllers for following circular trajectories are obtained by a trial‐and‐error approach rather than a model‐based design.FindingsThe autonomous ornithopter successfully circulates the pre‐described radius with the constant altitude and the result shows that control strategies proposed in this study are sufficient to implement the autonomy of ornithopter flight.Originality/valueThe autonomous flight of ornithopter is firstly conducted in a confined indoor environment by using the motion capture system and the control performance is evaluated in terms of position errors.
Optimal control and line‐of‐sight guidance formation flight
Authors: Sadraey Mohammad H. 
Published: July 2013

PurposeThe purpose of this paper is to design an integrated guidance and control design for a formation flight of four unmanned aerial vehicles to follow a moving ground target.Design/methodology/approachThe guidance law is based on the line‐of‐sight. The control is optimal. The guidance law is integrated with the optimal control law and is applied to a linear dynamic model.FindingsThe theoretical results are supported by the numerical simulations that illustrate a coordinated encirclement of a ground maneuvering target.Research limitations/implicationsA linear dynamic UAV model and a liner engine model were employed.Practical implicationsThis is expected to provide efficient coordination technique required in many civilian circular formation UAV applications; also the technique can be used to provide a safe environment required for the civil applications.Social implicationsThe research will facilitate the deployment of autonomous unmanned aircraft systems in various civilian applications such as border monitoring.Originality/valueThe research addresses the challenges of coordination of multiple unmanned aerial vehicles in a circular formation using an integrated optimal control technique with line‐of‐sight guidance.
Students' perceptions on environmental management of HEIs and the role of social capital
Authors: Jones Nikoleta , Roumeliotis Spiridon , Iosifides Theodoros , Hatziantoniou Maria , Sfakianaki Eleni , Tsigianni Eleni , Thivaiou Kalliopi , Biliraki Athina , Evaggelinos Kostas 
Published: July 2013

PurposeThe aim of the present study is to contribute to the discussion introducing the concept of social capital as a significant parameter influencing students' perceptions concerning greening initiatives in HEIs.Design/methodology/approachA theoretical analysis is presented concerning the possible links of social capital components with students' perceptions on environmental management initiatives. Furthermore, the results of an empirical study are presented exploring these issues from the perspective of students, both through quantitative and qualitative social research methods.FindingsThe empirical study reveals that students' social capital is connected with their perceptions for the environmental management of the university.Social implicationsThe paper underlines the importance of examining and taking into consideration social factors prior to the implementation of environmental management initiatives in HEIs, in order to increase their effectiveness.Originality/valueThe paper is a first attempt to empirically explore the influence of students' social capital on their perceptions for environmental management initiatives in higher education institutions.
Implementation of alternative transport networks in university campuses
Authors: Pitsiava‐Latinopoulou Magda , Basbas Socrates , Gavanas Nikolaos 
Published: July 2013

PurposeIn order to alleviate the impacts of traffic congestion that undermine the mobility and accessibility conditions of the Aristotle University campus, the paper aims at the presentation and description of a complementary network of alternative modes (i.e. pedestrian and bicycle) and the discussion of the appropriate measures for its successful implementation in the campus.Design/methodology/approachThe methodological approach of the paper is twofold: the overview of good practices for implementing cycling and pedestrian networks in European university campuses in an attempt to identify an integrated activity framework compatible to the European approach; and a questionnaire survey for the assessment of the modal split for trips towards and from the campus and the current mobility and accessibility conditions for pedestrians and cyclists in the Aristotle University campus.FindingsThe successful implementation of alternative transport networks in university campuses depends on the specific features of each campus in relation to the urban transport network and the commuting characteristics of staff and students. In the case of the Aristotle University campus, the modal split shows that 2/3 of campus‐related trips are conducted by motorised transport while the share of bicycle use is very low. In order to promote cycling and walking in the campus, a combined approach must be adopted based on five fields of activity: policy; research; design; support and promotion; and monitoring.Research limitations/implicationsThe paper derives from the research initiatives of the Aristotle University's Sustainable Mobility Committee, which was founded in order to promote sustainable solutions for the campus's transport system.Originality/valueThe paper provides a common and integrated activity framework for the implementation of an alternative transport network in a university campus based on the extensive overview of European experience. Furthermore, it develops for the first time a full proposal for the implementation of a pedestrian and bicycle network in the Aristotle University campus, which is one of the oldest and largest campuses in Greece.
Mapping the terrain of educational leadership and management in East Asia
Authors: Hallinger Philip , Bryant Darren 
Published: July 2013

PurposeThe purpose of this paper is to gain perspective on the extent to which the vision for knowledge production in East Asia set forth by Bajunid, Cheng, Hallinger, Walker, Dimmock and others almost 20 years ago has been fulfilled. The authors undertook an effort to map the terrain of knowledge production in educational leadership and management in East Asia since the year 2000. Their method of mapping this terrain involves the analysis of trends in publication of articles about and/or from East Asia in eight core educational leadership and management journals.Design/methodology/approachThe authors’ methodology employed a descriptive, quantitative form of literature review. They identified a clearly delimited body of literature, comprised of all articles published about or from East Asia between 2000 and 2011 in eight core educational leadership and management journals. Then they employed a systematic search for information within that literature and analyzed trends across the studies. This allowed them to map the terrain of recent research on educational leadership and management within East Asia.FindingsThe volume of knowledge production from East Asia between 2000 and 2011 consisted of less than 6 per cent of total output in the relevant journals. Although there was a discernible increase in the annual rate of publication over the course of the 12‐year period, the authors treat the increase as relatively unimportant given the small volume. A substantial majority of the publications not only came from a few societies, but from a small number of universities. Citation analyses were highly consistent with all of the above trends, and reinforced a picture of limited impact.Research limitations/implicationsThe authors’ study focused on a clearly delimited region, East Asia. Although they believe that the study may have implications for other regions of the developing world, they do not speculate on the extent of relevance. The authors intentionally limited their definition of the corpus of knowledge to a specific set of international refereed journals that are published in English. This ignores the potential contributions of conference papers, books, book chapters, research handbooks, domestic journals, and even other international journals in which educational leadership scholars publish.Originality/valueTo the authors’ knowledge, there have been no efforts undertaken to understand the nature of knowledge production in educational leadership and management in East Asia. When approaching this review in 2012, the authors were not under the illusion that the regional knowledge base would be either overly dense in terms of the concentration of studies within particular areas or broad in scope. However, future scholarship may be aided by this systematic assessment of the current knowledge base on educational leadership in the region.
Are a culture of trust and morality associated with paying and repaying behavior?
Authors: Tammi Timo 
Published: July 2013

PurposePaying and repaying behavior are financial functions of great interest to private financial actors and public regulators, as also to academic researchers. The purpose of the paper is to empirically analyse paying and repaying behavior by combining theoretical insights from an emerging field in economics known as “culture and finance” with ideas from the economic analysis of social capital and trust in the context of different regulatory systems.Design/methodology/approachThe present paper investigates with the help of panel data whether a culture of social trust and the scope of morality have an influence on paying and repaying behavior in different European and OECD countries.FindingsThe analysis shows that culture has an effect on firms' credit losses from the customers' payment defaults, on the overall riskiness of paying behavior and on the level of non‐performing bank loans. Also the complexity of law‐based regulation has an influence on paying and repaying behavior. The analysis also shows that high trust and morality are associated with less complex regulation and vice versa.Practical implicationsThe results help private financial actors, regulators and public policy makers to design more appropriate behavioral environments for paying and repaying.Originality/valueThe paper provides the first analysis of an important issue and it serves both practical interest and further research on the topic.
Knowledge and the political economy of TARP
Authors: Hoffman Michael E.S. 
Published: July 2013

PurposeThe purpose of this paper is to establish the consensus about the tremendous economic success of the Troubled Asset Relief Program (TARP) and explore theories of popular disapproval of TARP.Design/methodology/approachThe analytical approach in this paper is a multivariate survey logit based on two Pew Research Center surveys that include questions on knowledge of and views on TARP. One survey is used to estimate a knowledge index of TARP that is applied to another survey to estimate the impact of knowledge on opinions of TARP.FindingsThe author finds that knowledge of TARP is dependent in particular on education, party affiliation, and sex. Controlling for partisan effects, views on TARP's effectiveness are distorted by limited knowledge of TARP in magnitudes that are politically significant.Practical implicationsDespite the severity and dramatic spillovers associated with banking crises, decisive interventions may prove difficult to defend in retrospect in light of ignorance and an inability to conceptualize the nature of the counterfactual.Originality/valueThis paper contributes to our understanding of the political economy of an important and controversial economic policy, in particular the roles of ideology and knowledge in accounting for public opposition to TARP. TARP is largely misunderstood. The author estimates a model of TARP knowledge based on this misconception, and shows that education, party affiliation/leaning, and sex are important predictors of TARP knowledge. By applying this model of TARP knowledge to a separate survey dataset, the author demonstrates that knowledge of TARP (along with political ideology) is an important predictor of support for TARP. By integrating two different surveys, he is able to better identify the role played by knowledge of TARP, rather than simply demographic characteristics.
Price sequences, perceived variability, and choice
Authors: Dolansky Eric , Vandenbosch Mark 
Published: July 2013

Purpose
– Sequences of prices are becoming more commonplace but there is limited research on their behavioral effects. The purpose of this paper is to determine if a sequence of past prices, and particularly its variance, has a strong effect on choice. Will people pay significantly more for a seller who has a more predictable history of past prices?

Design/methodology/approach
– Past theory is drawn upon to create predictions regarding how individuals will perceive and value past sequences of prices. One experimental study is conducted to test preference and choice based on past price sequences.

Findings
– Individuals more frequently choose a vendor with past prices that fall into a predictable pattern, even when doing so results in higher future prices to be paid.

Originality/value
– This paper not only tests notions that have anecdotal support (e.g. preference for fixed vs floating interest rates, despite the higher cost of doing so), but also demonstrates that a person
'
s distaste for perceived variability is sufficiently strong so as to result in a willingness to pay 40 percent more for this predictability.
Entrepreneurial education: meeting needs better
Authors: McAuley Andrew 
Published: July 2013

PurposeThe purpose of this paper is to offer a perspective on the economic performance of small to medium‐sized enterprises' (SMEs') innovation and education in the context of entrepreneurship.Design/methodology/approachA wide ranging narrative supported by examples.FindingsThere is still plenty of opportunity for innovation in entrepreneurship education.Research limitation/implicationsThere is real and timely opportunity to follow a research agenda in this area which would be of significant benefit to public policy.Practical implicationsBuilding pathways to entrepreneurial effectiveness is a challenge but could lead to effective public policy.Social implicationsEconomic activity cannot be undertaken in isolation from the cultural context. Entrepreneurship is a force for social change.Originality/valueThe discussion offers a personal viewpoint and poses questions.
On the integration of European capital markets
Authors: Alexakis Panayotis , Vasila Anna 
Published: July 2013

PurposeThe paper aims to investigate European equity market integration by analyzing volatility spillover effects between selected indices of high liquidity from the major regulated European equity markets.Design/methodology/approachIn undertaking the empirical analysis, data for major European stock market indices were utilised. The conditional variance of the VAR‐GARCH model for each pair of indices is examined.FindingsThe results provide evidence on strong EU equity market integration. The findings in general suggest a high degree of European equity market interconnection. This situation is depicted through strong effects from one European equity market to the other, as well as through significant feedback effects between them.Originality/valueThe high level of interconnection found among the EU stock markets exerts significant influence on the efficient operation of each market and on asset and index pricing, which has therefore to be taken into account by investors and traders as market prices are set in common.
Analysis of cross‐border and domestic mega‐M&As of European commercial banks
Authors: Nnadi Matthias , Tanna Sailesh 
Published: July 2013

PurposeThis paper aims to examine value gains to acquirers in large commercial bank mega‐mergers (with transaction values over £1 billion) that occurred in the European Union during the period 1997‐2007, distinguishing between domestic and cross‐border transactions.Design/methodology/approachBased on a sample of 62 bank mega‐mergers, an event study methodology is employed using a market model to determine cumulative standardised abnormal returns (CSAR) to acquiring banks around the announcement date of merger deals. This is followed by cross‐sectional regression to determine specific characteristics driving acquirers' CSAR.FindingsCross‐border bank mergers have been more frequent in recent years, reflecting a growing trend of banking sector consolidation in the EU. However, such mergers are found to yield significant negative announcement period acquirer returns, while domestic deals have marginally negative but insignificant returns. The operational cost efficiency and capital strength of acquiring banks are found to be significant in influencing excess returns.Research limitations/implicationsConstraints on data availability limited the scope for sensitivity analysis and incorporation of target characteristics in the cross‐sectional regression of drivers affecting acquirers' CSAR. Further research is aimed to address these issues.Practical implicationsEvent study and regression results indicate that potential downside risks are judged by market participants to outweigh the benefits from cross‐border M&As in the retail banking market despite evidence of increased financial sector consolidation in the EU.Originality/valueThe study reflects the recent period of increased cross‐border banking consolidation in the EU and reveals findings that differ in some respects from previous studies on EU bank M&As.
How bureaucracy and corruption affect economic growth and convergence in the European Union
Authors: Papaconstantinou Panagiota , Tsagkanos Athanasios G. , Siriopoulos Costas 
Published: July 2013

PurposeThis paper aims to examine the impact of corruption and bureaucracy on economic growth in Greece as measured by the growth rate of per capita GDP. Also, using the mean per capita GDP of the EU as a benchmark, it seeks to investigate the convergence timing of Greece with the EU.Design/methodology/approachThe empirical approach taken is based on beta convergence theory.FindingsThe results confirm the negative impact of bureaucracy and corruption on economic growth. However, the corruption exerts a more significant influence on growth than bureaucracy. Also, the timing of convergence of Greece with the EU is found to be 37 years.Originality/valueThe robustness of these results is based on the use of a relatively new econometric method which is the Markov conditional bootstrap.
Peter Drucker and the academy
Authors: Wartzman Rick 
Published: July 2013

PurposeThe purpose of this paper is to discuss the influence of Peter Drucker's ideas in the academy.Design/methodology/approachThe author presents a profile of Peter Drucker, discussing his ideas and his relationship with the scholarly community.FindingsPeter Drucker was not particularly fond of the academic world and served in a non‐traditional role in the academy. Yet his prolific writing and methodological rigor has impacted generations of scholars and practicing managers. His work constantly looked to the future, identified crucial emerging trends that would affect management, thought and worked in a trans‐disciplinary fashion, and focused on practical implications that would make a difference.Research limitations/implicationsThe paper suggests new approaches to consider, to enhance academic engagement with practice.Originality/valueThis paper points out the significant contributions that Peter Drucker made to management thinking and research.