bluuebunny/crossref_metadata_2025_split huggingface dataset:
FEATURES OF THE MICROANATOMY OF THE UMBILICAL VEIN IN THE FETAL AND EARLY NEONATAL PERIODS OF ONTOGENESIS
Authors: Zabrodska O. 
Published: February 2025

Studying the microanatomy of the umbilical vein during the fetal period is important because of its critical role in providing the fetus with oxygen and nutrients necessary for normal development. Analysis of the microanatomical features of the umbilical vein allows us to identify the key mechanisms of adaptation of the vascular system to intrauterine conditions, which is important both for fundamental science and clinical practice. Data on age-related changes in the structure of the umbilical vein can help in the diagnosis and prevention of complications associated with placental blood circulation disorders.
The purpose of the study is to establish the peculiarities of the microstructure of the umbilical vein during the fetal period. Material and methods. 70 objects of fetuses and 7 newborns were used for the study. To achieve the goal, a complex of morphological research methods was used, which includes macro-microdissection, production of topographic-anatomical sections, radiography, and morphometry.
The results. The wall of the umbilical vein in the fetal period has a multi-layered structure, which includes the endothelium (inner shell – intima), subendothelial layer, muscle layer (middle shell – media) and adventitia (outer shell). This structure provides mechanical stability of the vessel and optimal conditions for blood transportation. The endothelial layer of the umbilical vein in fetuses is characterized by a dense arrangement of cells that actively synthesize glycosaminoglycans, which contributes to uniform blood flow and protection of the vessel wall from mechanical damage. The subendothelial layer has a variable thickness, which is associated with adaptive changes to hemodynamic conditions.
A large number of fibroblasts and collagen fibers were found in it, which ensure the elasticity and flexibility of the vessel wall. The muscle layer of the umbilical vein is represented by smooth muscle cells that form circularly oriented bundles. This layer plays an important role in maintaining vessel tone and ensuring constant blood flow. The adventitia consists mainly of loose connective tissue that contains blood vessels and nerve fibers that provide metabolic support and innervation of the vein wall.
Conclusions. Therefore, in early fetuses, the inner membrane of the wall of the umbilical vein is thin and characterized by a weak development of smooth myocytes, none of the fibers are noted. At the end of the fetal period, all layers of the umbilical vein acquire the greatest development: the outer adventitian layer becomes stronger, the middle layer contains many smooth myocytes, and collagen fibers appear first, and later elastic ones. For the first time, many macrophages, phagocytes, and fibroblasts can be seen in the layers of the umbilical vein wall. In newborns, the number of smooth myocytes and macrophages increases several times, leukocytes and lymphocytes appear.
COMPARATIVE CHARACTERISTICS OF MORPHOFUNCTIONAL CHANGES IN KIDNEY PARENCHYM AND NEPHRON STRUCTURES AFTER EXPLOSION-INDUCED EXPERIMENTAL INJURY
Authors: Kosharnyi V. , Kahramanyan A. , Rutgayzer V. , Gruzd V. , Kosharnyi D. , Voloshyn V. 
Published: February 2025

Under the conditions of simulated explosive-induced experimental trauma and three experimental models, we carried out the impact of a blast wave on the renal parenchyma and nephron structures using a patented device (pat. 146858 Ukraine, MPK G09B23/28) and analyzed macroscopic and microscopic changes that are specific to the renal parenchyma of rats at different periods of exposure. Based on all the studies conducted, it can be stated that under the conditions of a blast wave on the first, seventh and fourteenth day, different, but morphofunctional, manifestations are manifested in impaired hemocirculation, the occurrence of edema and impaired renal function, and especially the nephron, the impairment of which, as a separate method, we investigated based on the results of a general analysis of rat urine. As a result of our work, comparative characteristics of changes in the morphology of the organ and its function were clarified. After the impact of the shock wave in the acute, early and late periods, not only morphological changes occur, but also changes in laboratory data and morphometric indicators. Macroscopically, these changes were manifested in a change in the external color - brighter and brighter in the acute, less - in the early and late period. According to the results presented in this study, pathological morphological phenomena were detected in the components of the nephron in the form of local edema of the perivascular spaces, blood supply disorders at the level of the microcirculatory bed. Functionally, glomerular disorders had consequences in changing quantitative laboratory indicators in urine tests, they were different in the acute, early and late periods, but in all terms of exposure, the only characteristic signs of the impact of the blast wave were - erythrocyturia, proteinuria and tripelphosphaturia.
THE WORK OF THE STUDENT SCIENTIFIC CLUB AT THE DEPARTMENT OF HISTOLOGY, CYTOLOGY AND EMBRYOLOGY OF THE IVAN HORBACHEVSKY TERNOPIL NATIONAL MEDICALUNIVERSITY OF THE MINISTRY OF HEALTH OF UKRAINE
Authors: Shuturma O. , Nebesna Z. , Hetmaniuk I. , Kulbitska V. , Ohinska N. 
Published: February 2025

Students&#39; research activities are an important means of organizing their academic work for in-depth study of various aspects of histology, cytology and embryology. An important stage in the formation of a future specialist is the student&#39;s independent work, during which teachers identify the most proactive and interested students who continue their research within the activities of the student scientific club of the department. The student scientific club, which was created at the Department of Histology and Embryology of the Ivan Horbachevsky Ternopil National Medical University of the Ministry of Health of Ukraine, contributes to the improvement of scientific training of higher education students, their organization, formation of scientific independence, responsible attitude to learning, development of communication skills between peers and team spirit. The main goal of the scientific club is to train well-rounded and highly qualified doctors. The members of the club are actively involved in modeling experiments, making histological microdissections, conducting morphometric studies, analyzing the morphological structure with a light microscope, and presenting the results of their work in scientific abstracts and articles. During the existence of the student scientific club at the Department of Histology and Embryology, its members annually win prizes at intra-university, inter-university and international scientific conferences and congresses.
CLINICAL ANATOMY OF THE ORAL CAVITY FLOOR
Authors: Khmara T. , Kuzniak N. , Ryznychuk M. , Zamorskii I. , Chernikova H. , Petryuk A. 
Published: February 2025

Modern development of dentistry and maxillofacial surgery requires thorough basic morphological studies of the oral cavity and surrounding tissues, as well as generalization of existing literature data. The analysis of modern scientific literature allows us to conclude that, despite a number of scientific anatomical works, the determination of ontogenetic transformations and individual anatomical variability of muscles and fasciae, blood vessels and nerves of the human oral cavity floor are topical issues of modern medicine.
The floor of the mouth is a complex of soft tissues (muscles, fascia, subcutaneous tissue, glands, blood vessels, and nerves) located between the mandible and the hyoid bone. The main muscle of the floor of the oral cavity is the paired maxillary hyoid muscle. There are two permanent gaps in the floor of the oral cavity: 1) between the posterior margin of the maxillomandibular muscle and the hyoid-lingual muscle; 2) between the muscle fiber bundles of the maxillomandibular muscle in the area of the anastomosis of the lingual and chin arteries. The inconsistent gap through which the tissues of the hyoid and suprahyoid areas are connected includes the gap of the oral diaphragm at the point where the &quot;diaphragmatic&quot; process of the hyoid gland enters it.
There are several intermuscular spaces between the muscles of the floor of the mouth, which play an important role in the spread of inflammatory processes in the floor of the mouth. Thus, above the maxillary hyoid muscle, there are 1) paired beds of sublingual salivary glands, or lateral cellular spaces of the floor of the mouth, which are bounded from above - by the mucous membrane that runs from the tongue to the gums of the lower jaw; from below - by the maxillary hyoid muscle; medially - by the tongue muscles; laterally - by the lower jaw; 2) an unpaired internal intermuscular space between the right and left hyoid and tongue muscles, containing a small layer of loose connective tissue, where deep inflammatory processes can develop; 3) paired intermuscular spaces between the hyoid and tongue muscles and the hyoid and tongue muscles.
Below the maxillomandibular muscle there are: 1) paired interfascial gaps between the subcutaneous neck muscle, which is covered by the superficial neck fascia, and the division of the superficial plate of the neck fascia proper, which forms the fascial vagina of the submandibular salivary gland; 2) unpaired musculofascial gap between the anterior belly of the biceps brachii and the maxillomandibular muscles.
The conducted meta-analysis of foreign and domestic literature will broaden the horizons of scientists, students and doctors about the morphological features of fascial and cellular spaces, muscles, main and additional sources of blood supply and innervation of the walls of the oral cavity, especially its floor, with regard to the forms of age-related anatomical variability.
Antimicrobial minimum inhibitory concentrations can be imputed from phenotypic data using a random forest approach
Authors: Anil Gayatri , Glass Joshua , Mosaddegh Abdolreza , Cazer Casey L. 
Published: February 2025

Abstract

Objective
Antimicrobial resistance (AMR) is a public health threat requiring monitoring across multiple sectors because AMR genes and pathogens can pass between humans, animals, and the environment. Idiosyncrasies in AMR data, including missing data and changes in testing protocols, make characterizing AMR trends over time and sectors challenging. Therefore, this study applied machine learning methods to impute missing minimum inhibitory concentrations.

Methods
Models were built using cattle-associated Escherichia coli from the National Antimicrobial Resistance Monitoring System. Random forest models were designed to predict the minimum inhibitory concentration of a given E coli isolate for 10 antimicrobials. Predictors included isolate metadata and the minimum inhibitory concentrations of other antimicrobials. Model performance was evaluated on held-out test data and 2 external datasets (E coli isolated from chickens and humans).

Results
Overall, the accuracy within 1 minimum inhibitory concentration category was over 80% for all 10 antimicrobials and over 90% for 5 antimicrobials on test data. Six of the models performed as well on both external datasets as on test data, whereas the remaining 4 had similar accuracy on the human dataset but lower on the chicken data.

Conclusions
These results indicate that the models can predict minimum inhibitory concentration values at a level of accuracy that would be helpful for imputation in resistance datasets.

Clinical Relevance
The imputation of missing minimum inhibitory concentrations would allow for better evaluation of AMR trends over time, helping inform stewardship policies. These models may also help streamline surveillance and clinical susceptibility testing because they suggest which antimicrobials need to be laboratory-tested and which can be extrapolated by modeling.
UNRAVELING INDONESIA'S PEATLAND POLICIES: IMPLICATIONS AND INCONSISTENCIES
Authors: M Mohd. Yusuf Daeng , Yusuf Fadly Daeng , Yuliani Febri , Zulkarnaini Zulkarnaini 
Published: February 2025

This article offers a legal perspective on the intricate web of Indonesian peatland policies, emphasizing their repercussions and inherent contradictions. Through an in-depth analysis of the legal frameworks and regulations governing peatland management in Indonesia, this study unravels the complexities and discrepancies present within these policies. It critically examines the repercussions stemming from these policies, shedding light on their unintended outcomes, including environmental, social, and economic ramifications. To address the complexities surrounding peatland policy in Indonesia, this article employes a multi-faceted legal research methodology. Primarily, it involves a doctrinal analysis, where relevant laws, regulations, and policies are systematically reviewed to identify inconsistencies and gaps. This study highlights the legal intricacies and challenges faced in implementing and enforcing peatland policy, ultimately seeking to propose a pathway for a more coherent, effective and harmonious legal framework to address the complexities of peatland management in Indonesia.
RECONSTRUCTION OF THE REGULATION GOVERNING AD HOC JUDGES IN THE INDUSTRIAL RELATIONS COURT OF INDONESIA
Authors: Pamungkas Yogo , Amriyati Amriyati , Yurikosari Andari , Setiawati Anda , Lie Ribka Yonathan 
Published: February 2025

This article examines the current construction of ad hoc judges within the Industrial Relations Court (PHI) and the resulting challenges impacting the settlement of industrial relations disputes. The primary objective of this analysis is to identify the legal problems associated with the present framework regulating ad hoc PHI judges and to propose solutions that mitigate these weaknesses. Utilizing a normative qualitative research methodology, this study relies on secondary data, employing both a statutory and conceptual approach to comprehension. Findings suggest that the existing construction of ad hoc PHI judges may compromise the objectivity of their decisions. This potential for bias can adversely affect fair conflict resolution, undermining trust in the judicial process. In light of these findings, the article advocates for a comprehensive reconstruction of the regulatory framework governing ad hoc judges. This would involve legislative reforms aimed at enhancing the performance and quality of PHI ad hoc judges. Such reforms could include stricter selection criteria, ongoing training programs, and mechanisms for accountability to ensure that these judges can make impartial and informed decisions. Ultimately, by addressing the identified legal shortcomings and implementing the proposed solutions, the integrity of the industrial relations dispute resolution process can be significantly improved. This approach not only aims to safeguard justice and fairness in industrial relations but also enhances the overall efficacy of the legal system in Indonesia. The insights underscore the urgent need for legislative action to foster a robust and unbiased framework for ad hoc PHI judges, ensuring equitable outcomes for all parties involved in industrial disputes.
Hot Drilling of SAE 1045 Steel Through Forging
Authors: Aguiar Fernando Silveira de , Martins Vinicius 
Published: February 2025

Objectives: This theoretical-experimental study aimed to reduce the manufacturing costs of eye bolts used in agricultural machinery by proposing an innovative approach that eliminates the need for machining by performing the hole drilling while the piece is still hot, thus optimizing the production process.

Theoretical Framework: The study is based on the principles of hot forging and punch drilling, exploring the interaction between the part design and computational simulation to improve the process. Aspects such as tool wear, forming parameters, and finite element analysis are considered to better understand the variables involved in production.

Method: The research was conducted through computational simulation using Simufact Forming software to evaluate cavity filling and predict the new geometry of the part. Following this, necessary devices such as die, punch, and deburring tool were designed and manufactured to implement the methodology in an industrial setting. The experimental phase involved producing and testing 4,000 units to evaluate the dimensional quality of the parts and the tool durability.

Results and Discussion: The results revealed that the new strategy of hot drilling eliminated the machining step, resulting in an annual savings of one ton of raw material and a reduction of 225 hours of CNC machine operation. Computational analysis showed a homogeneous response without structural defects, and the tool exhibited moderate wear without compromising the final product’s quality.

Implications of the Research: The findings of this study demonstrate the feasibility of replacing machining with hot drilling, yielding significant gains in productivity, sustainability, and industrial competitiveness.

Originality/Value: This proposal is innovative in presenting an efficient alternative for manufacturing forged parts, contributing significantly to cost reduction and environmental impact mitigation in the metalworking industry. The combination of hot forging and punch drilling offers an unprecedented solution with potential substantial benefits to the agricultural machinery industry.
Pengembangan Sistem Manajemen Sarana Dan Prasarana, IT, Serta Laboratorium Di SMK Telekomunikasi
Authors: Putri Nabella  , Rudy Herteno  , Setyo Wahyu Saputro  , Friska Abadi  , Muhammad Itqan Mazdadi  
Published: February 2025

Bidang Sarana dan Prasarana, IT, serta Laboratorium di SMK Telekomunikasi menghadapi tantangan dalam pengelolaan data yang tersebar di berbagai file Microsoft Excel, menyebabkan kesulitan dalam pengumpulan laporan untuk audit dan sertifikasi. Penelitian ini bertujuan mengembangkan sistem manajemen terpadu menggunakan framework CodeIgniter 4, PHP, dan MySQL dengan metode Rational Unified Process (RUP) dan desain Unified Modelling Language (UML). Sistem ini dirancang untuk menyelaraskan pengelolaan data dan memfasilitasi penyajian informasi yang efisien. Hasil pengujian black box menunjukkan tingkat keberhasilan 100%, sementara user acceptance testing memperoleh skor 92% dengan predikat sangat baik. Implementasi sistem ini diharapkan meningkatkan efisiensi dan efektivitas manajemen sarana, prasarana, IT, dan laboratorium di SMK Telekomunikasi, memberikan kontribusi signifikan terhadap peningkatan kualitas pengelolaan dan kepuasan pengguna.

Abstract.
The Facilities and Infrastructure, IT, and Laboratory Department at SMK Telekomunikasi faces challenges in managing data scattered across various Microsoft Excel files, resulting in difficulties in compiling reports for audits and certifications. This research aims to develop an integrated management system using the CodeIgniter 4 framework, PHP, and MySQL, employing the Rational Unified Process (RUP) methodology and Unified Modelling Language (UML) design. This system is designed to streamline data management and facilitate efficient information presentation. The results of the black box testing showed a success rate of 100%, while the user acceptance testing scored 92% with an excellent rating. The implementation of this system is expected to enhance the efficiency and effectiveness of managing facilities, infrastructure, IT, and laboratories at SMK Telekomunikasi, significantly contributing to improved management quality and user satisfaction.
Attitude ludique et sémiotique de l’identité : la tactilité cinétique dans les jeux vidéo
Authors: D’Armenio Enzo 
Published: February 2025

Dans cet article, notre propos est d’analyser le rôle de la tactilité dans les jeux vidéo et sa contribution à la construction de leur dynamique de sens. Dans la première partie de l’article, nous discuterons du concept d’attitude ludique décrit par Jacques Henriot et Sébastien Genvo. Il ne s’agit pas d’une propriété ontologiquement afférente aux objets, bien que les jeux soient des objets prédisposés à encourager cette attitude : chanter avec une fourchette pendant un repas revient à la transformer par une pratique ludique en un simulacre d’objet de chant et donc à encourager d’autres individus à reconnaître et à adopter la même attitude. À la lumière de la sémiotique des pratiques, nous définirons l’attitude ludique comme l’inflexion particulière d’une pratique sémiotique qui, en convoquant des modèles de schématisation et d’accommodation d’une autre situation sémiotique, dédouble les rôles identitaires tout en maintenant active la transduction co-structurante entre ces deux situations. Cela nous permettra, d’une part, de distinguer cette attitude du régime de croyance de la fiction et, d’autre part, de mettre en évidence le travail identitaire au cœur de toute sémiose. Dans la deuxième partie de l’article, nous tenterons d’analyser la tactilité particulière déployée par les jeux vidéo. À partir des champs sensibles identifiés dans le cadre de la sémiotique du corps — en particulier la sensori-motricité, le champ des mouvements intimes intransitifs et le champ transitif — nous examinerons la manière dont ces champs contribuent à la syntaxe figurale des jeux vidéo. Notre thèse est que les jeux vidéo imposent des restrictions considérables au champ plus large des pratiques ludiques et configurent une tactilité cinétique particulière : l’accès aux expériences de jeux vidéo implique la réalisation de mouvements sur une interface et la transformation de ces mouvements en mouvements dans les mondes numériques. La discussion de l’articulation et des limites de cette tactilité nous permettra d’examiner comment l’attitude ludique est réalisée dans les jeux vidéo à travers une corrélation constitutive entre mécanismes d’immersion cinétique et mécanismes d’interprétation réflexive.
Matière, plasmaticité et modes du sensible. La praxis énonciative de l’animation stop-motion et son application aux jeux vidéo
Authors: Conde Juan Alberto 
Published: February 2025

Cet article propose d’aborder la « tactilité du visuel » à travers la technique d’animation en stop-motion et la manière particulière dont cette technique fait usage de la photographie, mais aussi d’objets et de matériaux modelés. Pour ce faire, on examine l’approche sémiotique de l’image photographique sous l’angle de la corporéité et des modes du sensible associés à la praxis énonciative (Dondero, Fontanille), ainsi que la manière singulière dont l’animation en stop-motion engage d’autres dimensions de la corporalité dans sa production et sa réception. Cette singularité est liée à ce que Cyril Lepot appelle la plasmaticité, un trait spécifique de l’animation qui réside dans sa capacité à représenter des matières, des textures et des objets à partir de matérialités différentes. Après avoir établi ce champ de la praxis énonciative du stop-motion, l’article examine l’usage de cette technique dans la conception de jeux vidéo tels que Feltopia ou The Neverhood (et ses suites), en avançant quelques hypothèses sur les possibilités de sens que la remédiation (Bolter et Grusin) de cette technique offre au domaine du design vidéoludique, notamment en ce qui concerne la possibilité d’offrir aux spectateurs une expérience de la « tactilité du visuel ».