bluuebunny/crossref_metadata_2025_split huggingface dataset:
766 – the Occurrence of Neurological Symptoms in Currently Abstinent Misusers of Alcohol
Authors: Khalily M.T. , Hallahan B. 
Published: July 2013

Background:Significant neurological symptoms may be overlooked because of the traditional view that the non-Korsakoff's psychosis, middle aged alcoholic misuser is neurologically preserved.Aims:In this study, we wanted to investigate the presence of neurological symptoms in individuals with misuse or dependence on alcohol who were abstinent for at least 1 month.Method:We used two scales from the Minnesota Multiphasic Personality Inventory-2 (MMPI-2) to ascertain the presence of both neurological symptoms (HEA-2) and symptoms of general health concern (HEA-3) in 70 individuals who had a diagnosis of alcohol misuse or dependence, who were abstinent for greater than 1 month.Results:Individuals reported significantly more neurological symptoms than general health difficulties (p0.001). We detected neurological symptoms, unlike general health difficulties in individuals who were abstinent from alcohol for 12 months. When we examined diagnostic subgroups, general health difficulties were most present in individuals with anxiety disorders; however, neurological difficulties were present across diagnostic groups.Conclusion:Neurological symptoms persist to a greater extent than general health concerns in individuals who previously were dependent or misused alcohol.
771 – Communicability and Regret as Tools to Modify Occurrence and Future Outcome in Cases of Deliberate Self Harm
Authors: Sinha V. , Sharma I. , Paswan R.K. , Khan H. 
Published: July 2013

Aims and objectives:To assess the presence of communicability and regret in cases of deliberate self harm in a tertiary care hospital. to establish relation of communicability as a preventive sign and regret as a good prognostic sign in cases of deliberate self harm.Methodology:All consecutive patients with deliberate self harm presented to the emergency department during a 1 year period were assessed on a preformed Performa designed by authors after being declared physically fit and were screened by Standardized Assessment of Personality Abbreviated Scale (SAPAS), PSLES, HAM-D and HAM-A.Result:Majority of respondents screened negative by SAPAS scoring. Most of the patient had significant stress in life .Most of them had marital conflicts, family conflicts and economic burden as major stressor leading to suicidal behavior. Verbal communication was the most common mode of communication. Most of the subjects 86.3% (69 out of 80) had severe regret about their attempt of deliberate self harm. It developed a high motivation in them not to attempt suicide next time in life.Conclusion:Most of the suicidal acts are impulsive in nature and are not associated with any psychiatric co morbidity. Our study showed that if communicability is enhanced and this is considered seriously, providing supportive care by family most of the suicidal acts can be avoided. Regret arising after the suicidal act can be used to motivate the subject of deliberate self harm to avoid repetition of future attempts.
772 – Prevalence and Predictors of Depression in Patients with Systemic Lupus Erythematosus: a Cross-sectional Study
Authors: Maneeton B. , Maneeton N. , Louthrenoo W. 
Published: July 2013

Objective:The purpose of this study was to estimate the prevalence and examine the predictors of depression in patients with systemic lupus erythematosus (SLE).Methods:This cross-sectional study was conducted in a rheumatology clinic of university hospital. All SLE patients met the revised American College of Rheumatology (ACR) classification were included in the study. Socio-demographic data and medications were recorded. Disease activity for SLE was assessed with the Mexican-SLE Disease Activity Index (Mex- SLEDAI). All subjects were screened for anxiety and depression by using the Hamilton Anxiety Rating Scale (HAM-A) and the Hamilton Depression Rating Scale (HAM-D), respectively. Multivariate linear regression analysis was used to determine predictors of depressive disorder.Results:A total of 62 SLE (61 for females and 1 for male) patients participated in the study. Based on the HAM-D and HAMA, rates of depression and anxiety in the SLE patients were 45.2 and 37.1%, respectively. the multiple linear regression analysis revealed that HAM-A score and younger age were significant predictors of depression in the SLE patients.Conclusion:The finding suggests that depression and anxiety are common in the SLE patients. in addition, high level of anxiety and younger age may increase the risks of depression. Because of the small sample size, further studies should be conducted to warrant these results.
778 – Association of Apathy with Frontal Lobe Dysfunction in Amnestic Mild Cognitiveimpairment and Alzheimer's Disease
Authors: George M. , Whitfield T. , Walker Z. 
Published: July 2013

Objectives:The primary aim of this study is to examine an association between apathy and frontal lobe dysfunction in patients with memory problems. We also aimed to look into the association between apathy severity and caregiver burden along with the relationship between apathy and praxis.Methods:This was a retrospective cross sectional study. We selected 160 consecutive patients diagnosed with Alzheimer's dementia and Amnestic Mild Cognitive Impairment who had a comprehensive battery of neuropsychological tests and a behaviour rating scale of interest for this study recorded in the database. Correlation between apathy with and without depression were tested against frontal lobe test including Trail making A, Trial making B, Letter Fluency, Ideational Fluency, Category Fluency, Abstract Thinking and Executive functioning subtest of CAMGOG-R. Similarly correlation analysis was also done to look into association between apathy and caregiver burden as well as praxis.Results:Statistically significant relationship were found between apathy and executive function scores, ideational fluency scores, abstract thinking and category fluency scores. Relationship between apathy and caregiver burden were highly significant. Further sub analysis, found apathy to be significantly associated with caregiver burden in both AD and aMCI patients.Conclusions:Apathy is associated with frontal lobe dysfunction especially impaired executive function and ideational fluency even when controlled for depression. It is highly associated with caregiver burden both in AD & aMCI .Hence early recognition and management of apathy is important in improving the prognosis of patients with AD & aMCI as well as their caregiver.
783 – Memantine - A Possible Startup Key of Antipsychotics in Resistant Schizophrenia
Authors: Marinescu G.-C. , Rob L.A. , Popa S.N. 
Published: July 2013

Introduction:Although there are many antipsychotics, resistant schizophrenia is still to be an extremely important problem in psychiatrists' practice.Objectives:Finding a new strategy, different from the ones in daily standardized practice, could give better perspectives for the outcome of the cases of resistant schizophrenia.Aims:Adding memantine for about six months to the last antipsychotic used in the treatment of resistant schizophrenia could be used as a method in order to induce a response to the treatment due to modulation of NMDA receptors.Method:Two study cases: patients diagnosed with schizophrenia paranoid type, many years ago, with many hospitalisations for psychotic episodes admitted into the hospital for a psychotic relapse. the patients were treated with 2 antipsychotics (each for 8 weeks and adequate dose) without response. Both cases had a common approach from the moment of failure of the second antipsychotic: adding memantine 20 mg per day to the second antipsychotic, maintained with the same dose from that moment.Results:Adding memantine to the last antipsychotic induced the remission in both cases of resistant schizophrenia. This association was made for a period of 6 months and after that the dose of memantine was progressively reduced in 2 weeks. We kept the antipsychotic as a main treatment. the remission was kept during the period of association and one year after the withdrawal of the memantine.Conclusions:We think that memantine modulation of NMDA receptors in combination with antipsychotic D2 receptor blockade can improve the response of resistant schizophrenia.
784 – Clinical Outcomes of Depot and Well Being Clinic- Results of Physical Health Checks
Authors: Wildin H. 
Published: July 2013

Background:Physical health of people suffering from severe mental illness is a neglected area. They suffer more than general population and they die earlier. Looking after such disadvantaged group of people is mandatory, to improve their outcome and quality of life. Monitoring current clinical practice is essential to try to improve it.Methods:37 Records of patients who were on long acting injectable antipsychotics, attending the Taylor centre were selected and reviewed to establish their physical care arrangement check against the POMT-UK. Type of antipsychotics, whether they suffer from metabolic syndrome or not, other physical illness was recorded.Results:Records lacked any reference to baseline arrangements of physical monitoring. Although they demonstrated high level of physical morbidity, care and records didn’t reflect adequate clinical care to this important problem.Discussion:This study demonstrated that Physical care of people with severe mental illness is still substandard and needs to be developed in order to prevent or identify physical problems earlier, to reduce morbidity of these patients and improve their life expectancy and quality of life.Conclusion:Physical care is an important aspect of care of people who suffer from severe mental illness total care. This study has demonstrated that this area is still neglected. Improvement in this area will improve the global outcome of these disadvantaged people.
790 – Dual Diagnosis of Mental Illness and Substance Abuse: An Egyptian Study
Authors: Rady A. , Salama H. , Elkholy O. , Shawky A. 
Published: July 2013

Background:The dual diagnosis of substance abuse and severe mental illness has been proposed by some authors to highlight the high frequency of such association. Our objectif was to determine the prevalence of dual diagnosis among mentally ill patients. as a secondary purpose, to describe the profile of patient at higher risk to develop dual diagnosis.Method:683 mentally ill patients were recruited from el Mamoura Psychiatric Hospital, they were assessed by the Arabic version of 6 item K6 scale, those scoring above 13 were submitted to a structured clininical interview SCID-I (Modules A-E), urine screening for drugs of abuse and complete history of substance abuse and other medical disciplines.Results:22% of the sample fulfill the diagnosis of dual diagnosis. Results reveals higher risk for dual diagnosis in patients younger in age, single, low socioeconomic state and low level of education. Those having dual diagnosis tend to have early onset, longer duration of illness, poor compliance, higher rate of smoking and increased number of relapses.Conclusion:Double diagnosis is an important issue that needs more focus in mental health services. Awareness of mental health providers about dual diagnosis is highly recommended.
793 – Dual Diagnosis of Personality Disorder and Substance Abuse: The Need for Awareness
Authors: Rady A. , Salama H. , Elkholy O. , Shawky A. 
Published: July 2013

Background:The dual diagnosis of substance abuse and severe mental illness has been proposed by some authors to highlight the high frequency of such association. Our objectif was to determine the prevalence of dual diagnosis among mentally ill patients and and particularly personality disorder patients. as a secondary purpose, to describe the profile of patient at higher risk to develop dual diagnosis.Method:683 mentally ill patients were recruited from el Mamoura Psychiatric Hospital, they were assessed by the Arabic version of 6 item K6 scale, those scoring above 13 were submitted to a structured clininical interview SCID-II for personality disorder, urine screening for drugs of abuse and complete history of substance abuse and other medical disciplines.Results:22% of the sample fulfill the diagnosis of dual diagnosis. 12% of the sample had personality disorder, 57.32% among the later were fulfilling diagnosis of dual diagnosis. Results reveals higher risk for dual diagnosis in patients younger in age, single, low socioeconomic state and low level of education. No difference between different personality disorder subtypes as regarding rate of dual diagnosis.Conclusion:Double diagnosis is an important issue that needs more focus in mental health services. Awareness of mental health providers about dual diagnosis is highly recommended.
794 – Treating Personality
Authors: Ishizuka Y. 
Published: July 2013

All psychiatric distress can be understood as the consequence of interaction between one's existing personality - the way one thinks, feels, and act - and life challenges.Traditional treatment approaches have focused on understanding and treating various form of distress (symptoms), or consequences of above mentioned interaction.Lifetrack therapy focuses squarely on personality, offering a quantifiable model of personality that can be tracked daily by the patients themselves on 41 parameters.Working with the patient and his/her partner, Lifetrack therapy focus on increasing their closeness beyond their previous maximum experience, provoking and overcoming waves of defense (symptoms) until it weakens and disappears by exhaustion.Results of 1,213 patients with all diagnosis treated with Lifetrack therapy showed that 50% reached a level of adjustment beyond their previous maximum level according to their own daily self-rating. Result was 4 times better when the patients were treated with their partners. of 224 patients with borderline personality disorder, the most challenging category of patient population, 70% reached or exceeded their previous maximum levels, with couples doing 10 times better than those without partners. 50% of BPD patients went through complete or near complete personality transformation.Lifetrack therapy experience suggests that psychiatric symptoms of distress can be effectively treated through changing the patients' existing personalities, raising threshold of tolerance of challenges in life.
796 – Suicide Attempts in Chronic Pain Patients. A Register Study
Authors: Stenager E.N. , Christiansen E. , Handberg G. , Jensen B. 
Published: July 2013

Introduction and aims:The Centre for Suicide Research, Odense, Denmark has since 1990 registered all suicide attempts and suicides in patients residing in the County of Funen, Denmark.The Pain Clinic, Odense University Hospital's receives patients with chronic pain from the whole region of Southern Denmark. This study is part of two studies from the Pain Clinic.The aims of the study have beenTo investigate whether patients treated in the Pain Clinic in the period 1/1 2004-31/12 2010 have an increased risk of suicide attempts compared with the background populationTo investigate whether the frequency of suicide attempts before the treatment in the Pain Clinic differs from the frequency of suicide attempts after treatment.Methods:Data about age, sex and time of treatment on patients treated in the Pain Clinic in the period are registered. Time and method of the suicide attempts are registered in Centre of Suicide Research. By registry linkages between patient registers from the Pain Clinic and the Registry of Suicide Attempt in the County of Funen it was possible to calculate any excess risk of suicide attempts in chronic pain patients in the study period.Results:The Incidence rate ratio for suicide attempts in our study for both sex and all age group are about 1 or lower, which means that the pain population in our study does not have an increased risk of suicide attempts.
797 – Social Implication of Group Psychoterapy on Dual Diagnosis
Authors: Mitric B. 
Published: July 2013

Introduction:Center for Mental Health in Kotor was opened in 2005. year. in the center we apply modern methods in the treatment of substance addiction.Objectives:Objectives of this project are to understand the current way of functioning and the possibility of making new decisions.Aims:Raise awareness on the harmful effects of heroin, for their own health care and social functioning.Methods:Formed by a group which has eleven members. Two females, nine males. Age from 25 to 33 years. the paper applied the new method of treatment decisions. Before and during treatment was carried out satisfaction surveys using Manchester Short Assessment of Quality of Life (MANSA).Results:Members of groups that are unrealistic estimate the degree of satisfaction with life have left the program or had the resistance of the group. Other members who have had a more realistic self-assessment, regularly participated in the program. Their results MANSA at the start of treatment, pointed to dissatisfaction with social functioning, economic status and interpersonal relationships. At the end of treatment, MANSA indicating satisfaction personal safety, satisfaction with people with whom they live, physical pleasure and mental health. Three members have found employment.Conclusions:Group psychotherapy of dual disorder has effect on the level of social functioning. Members of the group have gained the insight that the concern for physical and mental health and social functioning is personal choice. Because group work and group work principles, the members have become more realistic in creating new life decisions.
800 – Prevalence of Prediabetes and Diabetes in Patients Treated with Antipsychotics
Authors: Steylen P. , van der Heijden F. , Verhoeven W. 
Published: July 2013

Introduction:Treatment with antipsychotic drugs is associated with an increased risk for glucose dysregulation.Hyperglycemia that does not fulfil diagnostic criteria for diabetes mellitus (DM) is known as prediabetes (preDM). PreDM is a strong risk factor for the development of DM and cardiovascular events.Objectives:To assess the prevalence of preDM and DM in patients on antipsychotic treatment.Aims:To compare cardiometabolic parameters between patients with normoglycemia, preDM and DM. in addition, incidence and reversal rates for preDM and DM were calculated in a one year follow-up.Methods:In a naturalistic cohort of 383 patients the fasting glucose and hemoglobin A1c criteria were applied. in addition, cardiometabolic parameters were measured. After one year, a second assessment was performed in 169 patients out of the total sample.Results:In the total sample, preDM and DM were present in 39% and 6% of antipsychotic treated patients, respectively. as compared to patients with normoglycemia, cardiometabolic parameters were more prevalent in patients with preDM. Although the majority of patients were diagnosed by the fasting glucose criterion, hemoglobin A1c contributed significantly to the number of patients identified. in a one-year follow-up, it was shown that the course of glucose metabolism can be dynamic.Conclusions:Systematic evaluation of glucose parameters in antipsychotic treated patients is warranted, in order to recognize glucose abnormalities at an early stage. Especially since fasting laboratory assessments are not required, including hemoglobin A1c as a diagnostic test is of additional value in identifying psychiatric patients (at risk for) DM.
801 – Comprehension and Companionship in the Emergency Department as Predictors of Treatment Adherence: a Prospective Study
Authors: Nitzan U. , Hirsch E. , Luria I. , Aviram S. , Walter G. , Bloch Y. 
Published: July 2013

Introduction:Lack of adherence to recommended treatment poses major clinical and economic challenges for psychiatry, and requires further study.Objectives and aims:We aimed to prospectively investigate the association between the level of understanding of psychiatric emergency department (ED) discharge recommendations and presence of a companion with short term treatment adherence.Methods:Sixty subjects were evaluated twice: upon ED discharge and a month later. Instruments included a structured questionnaire based on the MacArthur Competence Assessment Tool for Treatment, MMSE, and corroboration of data with the computerized hospital medical file.Results:There was a significant association between patient understanding and adherence with medication instructions (p< .01) and adherence to psychiatric follow-up (p< .05). There was also an association between the presence of a companion and adherence to medication instructions (x2(1)=7.0, p< .01).Conclusions:Ensuring patients' understanding of treatment recommendations and encouraging the company of patients are achievable, practical strategies that may improve adherence and thereby promote better outcomes.
819 – The Interpersonal Theory of Suicide and Adolescent Suicidal Behavior
Authors: Barzilay S. , Snir A. , Feldman D. , Apter A. 
Published: July 2013

Studies of suicidal behaviour have provided valuable information about the risk factors associated with these behaviors, yet there is not much information about predictors of transitions from suicidal thoughts to actual suicide behavior.The current study aims to elucidate the mechanisms in which suicidal ideation emerges over time and how suicidal ideation can lead to suicidal actions.We attempt to determine the effects of psychopathology, non-suicidal self-injury (NSSI) and risk behaviors on suicidal behavior. This is examined through our model of youth suicidal behavior based on the theoretical framework of Joiner's Interpersonal Theory of Suicide.Methods:The prospective study design included baseline two follow-up assessments within a year. Follow-up sample included a total of 708 adolescents from schools throughout Israel. the students completed self-report questionnairesregarding suicide ideation and attempts, psychopathology, life style, socio-demographic background, non-suicidal self-injury, life events and social support.Results:Results indicate that interpersonal distress and internalizing disorders at baseline predicted later levels of suicidal ideation. the effects of interpersonal factors on ideation were partly or fully mediated by internalizing symptoms. We also found that increases in suicidal ideation and in engagement in risk behaviors and NSSI over time were associated with the occurrence of a suicide attempt within the follow up period.Conclusions:The model identifies the different phases along the path to suicidal behavior, and risk factors associated with each phase. Hopefully this model will improve our understanding of the short-term course of suicidal behavior among adolescents, which may lead to potential improvements for intervention and prevention.
824 – Social Functioning in Schizophrenia Offspring
Authors: Ienciu M.L. , Bredicean C.A. , Romosan F. , Giurgi-Oncu C.I. 
Published: July 2013

Aim:Between the risk factors for developing a first episode psychosis, social functioning is considered to be one of the most important factors.The aim of the study is to compare social functioning in schizophrenia offspring and controls, and to determine possible associations between social functioning and prodromal symptoms.Methods:The study examined social functioning (by using the Social Functioning Scale) in 25 Schizophrenia offspring seeking psychiatric help for different problems, and 25 healthy controls.Clinical status was assessed with the Brief Psychiatric Rating Scale, HAM-D and HAM-A.Results:Schizophrenia offspring had significantly more social functioning deficits than controls. Social functioning was most strongly associated with depression and anxiety symptoms and less with minor psychotic symptoms.Conclusions:Social functioning deficits precede the onset of first episode psychosis, especially in persons at risk and, therefore, it could represent an early detection sign. Association with depression and anxiety symptoms should be an early intervention point.