bluuebunny/crossref_metadata_2025_split huggingface dataset:
Can the breast screening appointment be used to provide risk assessment and prevention advice?
Authors: Evans D. Gareth , Howell Anthony 
Published: June 2015

AbstractBreast cancer risk is continuing to increase across all societies with rates in countries with traditionally lower risks catching up with the higher rates in the Western world. Although cure rates from breast cancer have continued to improve such that absolute numbers of breast cancer deaths have dropped in many countries despite rising incidence, only some of this can be ascribed to screening with mammography, and debates over the true value of population-based screening continue. As such, enthusiasm for risk-stratified screening is gaining momentum. Guidelines in a number of countries already suggest more frequent screening in certain higher-risk (particularly, familial) groups, but this could be extended to assessing risks across the population. A number of studies have assessed breast cancer risk by using risk algorithms such as the Gail model, Tyrer-Cuzick, and BOADICEA (Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation Algorithm), but the real questions are when and where such an assessment should take place. Emerging evidence from the PROCAS (Predicting Risk Of Cancer At Screening) study is showing not only that it is feasible to undertake risk assessment at the population screening appointment but that this assessment could allow reduction of screening in lower-risk groups in many countries to 3-yearly screening by using mammographic density-adjusted breast cancer risk.
Rewriting the blueprint of life by synthetic genomics and genome engineering
Authors: Annaluru Narayana , Ramalingam Sivaprakash , Chandrasegaran Srinivasan 
Published: June 2015

AbstractAdvances in DNA synthesis and assembly methods over the past decade have made it possible to construct genome-size fragments from oligonucleotides. Early work focused on synthesis of small viral genomes, followed by hierarchical synthesis of wild-type bacterial genomes and subsequently on transplantation of synthesized bacterial genomes into closely related recipient strains. More recently, a synthetic designer version of yeast Saccharomyces cerevisiae chromosome III has been generated, with numerous changes from the wild-type sequence without having an impact on cell fitness and phenotype, suggesting plasticity of the yeast genome. A project to generate the first synthetic yeast genome - the Sc2.0 Project - is currently underway.
Higher-order Lipschitz mappings
Authors: Ezearn Jeffery 
Published: June 2015

AbstractWe study self-mappings on complete metric spaces, which we refer to as higher-order Lipschitz mappings. These mappings generalise Lipschitz mappings, the latter which are equivalent to first-order Lipschitz mappings studied in this paper. The main result of this paper is to extend the Banach fixed point theorem (and an often-cited generalisation) to higher-order contraction mappings. We also present results on the problem of local Lipschitzity of these higher-order Lipschitz mappings.
Quantifying in from a Fregean Perspective
Authors: Yalcin Seth 
Published: June 2015

As Quine (1956) observed, the following sentence has a reading which, if true, would be of special interest to the authorities:(1) Ralph believes that someone is a spy.This is the reading where the quantifier is naturally understood as taking wide scope relative to the attitude verb and as binding a variable within the scope of the attitude verb. This essay is interested in addressing the question what the semantic analysis of this kind of reading should look like from a Fregean perspective—a perspective according to which attitude states are generally relations to structured Fregean thoughts composed of senses. The Fregean view faces a challenge of compositionality here. This essay describes the challenge and offers a response on the Fregean's behalf.
agINFRA: a research data hub for agriculture, food and the environment
Authors: Drakos Andreas , Protonotarios Vassilis , Manouselis Nikos 
Published: June 2015

The agINFRA project (www.aginfra.eu) was a European Commission funded project under the 7th Framework Programme that aimed to introduce agricultural scientific communities to the vision of open and participatory data-intensive science. agINFRA has now evolved into the European hub for data-powered research on agriculture, food and the environment, serving the research community through multiple roles.Working on enhancing the interoperability between heterogeneous data sources, the agINFRA project has left a set of grid- and cloud- based services that can be reused by future initiatives and adopted by existing ones, in order to facilitate the dissemination of agricultural research, educational and other types of data. On top of that, agINFRA provided a set of domain-specific recommendations for the publication of agri-food research outcomes. This paper discusses the concept of the agINFRA project and presents its major outcomes, as adopted by existing initiatives activated in the context of agricultural research and education.
Study Protocol: The influence of Running Therapy on executive functions and sleep of prisoners
Authors: Meijers Jesse , Harte Joke , Meynen Gerben , Cuijpers Pim 
Published: June 2015

Background: Executive dysfunction appears to be related to increased recidivism. Of note is that sleep disturbances, which are highly prevalent in prisons, may attenuate executive functions. Thus, improving executive functions, either directly or indirectly through the improvement of sleep, may reduce recidivism. It is hypothesised that physical exercise, in the form of Running Therapy, has a direct positive effect on executive functions as well as an indirect effect through the improvement of sleep.Methods/Design: Seventy two (N = 72) detainees in various penitentiary institutions in the Netherlands will be recruited in this study. A baseline measurement, including six neuropsychological tests of the Cambridge Neuropsychological Test Automated Battery (CANTAB), an assessment of sleep quality and duration using the Actiwatch (Actiwatch 2, Philips Respironics, Murrysville, PA, USA) and various other measurements will be administered before the start of the treatment. After 3 months of Running Therapy, participants will be assessed again with the same tests for neuropsychological and physical functioning. Primary outcomes are executive functioning and various sleep variables.Discussion: This study will be the first to investigate the possible influence of Running Therapy on the cognitive functioning, sleep and aggression in prisoners.
Chitosan membranes in a rat model of full-thickness cutaneous wounds: healing and IL-4 levels
Authors: Nordback P. H. , Miettinen S. , Kääriäinen M. , Haaparanta A-M. , Kellomäki M. , Kuokkanen H. , Seppänen R. 
Published: June 2015

Objective: The aim of this study was to examine the effect of chitosan membrane on wound healing. Method: The effect of chitosan membranes was evaluated in an experimental rat model. On day 0, circular full-thickness skin sections were excised from the scalps of rats. The wounds were then measured and the surrounding area tattooed. Rats were sacrificed either immediately after excision, or randomised into control and chitosan groups and followed up on day 3, 7, 14 or 21. Control group wounds were covered with Aquacel (wound dressing). Chitosan group wounds were covered with chitosan membranes and the wound dressing. Wounds and the distances between the tattooed marks were measured on follow-up, the wound sites were harvested and histologically examined, and serum interleukin (IL-4) levels were analysed. Results: A total of 54 rats were examined and all time points included 6 control and 6 chitosan treated animals, except for day 0 which consisted of control animals only. On day 3, wounds in the chitosan group were significantly (p<0.05) smaller (60 ± 6% versus 78 ± 19% of the original wound area) than in the control group. Chitosan membranes were found to degrade at the wound sites between days 7 and 14. Leukocyte counts were lower in the chitosan group than in the control group on day seven (p<0.05). IL-4 levels were significantly higher on day 7 (p<0.001) and 14 (p<0.001) in the chitosan group. Conclusion: According to our results chitosan membrane may promote early wound healing, reduce inflammation and affect the IL-4 pathway, however, the membrane degrades at the wound site after day 7.
Historical Differences in School Term Length and Measured Blood Pressure: Contributions to Persistent Racial Disparities among US-Born Adults
Authors: Liu Sze Yan , Manly Jennifer J. , Capistrant Beatrix D. , Glymour M. Maria 
Published: June 2015

Introduction
Legally mandated segregation policies dictated significant differences in the educational experiences of black and white Americans through the first half of the 20th century, with markedly lower quality in schools attended by black children. We determined whether school term length, a common marker of school quality, was associated with blood pressure and hypertension among a cohort of older Americans who attended school during the de jure segregation era.

Methods
National Health and Nutrition Examination Survey I and II data were linked to state level historical information on school term length. We used race and gender-stratified linear regression models adjusted for age, state and year of birth to estimate effects of term length on systolic and diastolic blood pressure (SBP and DBP) and hypertension for US-born adults. We also tested whether correcting years of schooling for term length differences attenuated estimated racial disparities.

Results
Among black women, 10% longer school term was associated with lower SBP, DBP and hypertension prevalence (2.1 mmHg, 1.0 mmHg, and 5.0 percentage points respectively). Associations for whites and for black men were not statistically significant. Adjustment for education incorporating corrections for differences in school term length slightly attenuated estimated racial disparities.

Conclusions
Longer school term length predicted better BP outcomes among black women, but not black men or whites.
Solvent-controlled diastereoselectivity in tryptophan-catalyzed Mannich reactions
Authors: Valero Guillem , León Carlos M. , Moyano Albert 
Published: June 2015

Abstract
Solvent effects in the L-tryptophan-catalyzed
Mannich reaction between hydroxyacetone and
glyoxylate imines have been examined. The use of a
DMSO/1-butanol (4:1 v/v) mixture as solvent at rt provided
the expected Mannich adducts in good yields, high
anti-diastereoselectivity (up to 10.3:1 anti/syn ratio) and
excellent enantioselectivities (up to >99.9% ee for the anti
isomer).
Synthesis of novel chiral bithiophenebased phosphine oxides as Lewis bases in organocatalytic stereoselective reactions
Authors: Rossi Sergio , Benaglia Maurizio , Cirilli Roberto , Benincori Tiziana 
Published: June 2015

Abstract
Novel enantiomerically pure tetramethylbithiophene
diphosphine oxides (tetraMe-BITIOPO)
featuring differently substituted aromatic rings at the
phosphorous atoms were synthesized, fully characterized
and isolated in enantiomerically pure form. The new
Lewis bases were tested as organocatalysts in two
different reactions involving trichlorosilyl compounds.
The introduction of electron donating substituents on the
aromatic rings connected to the phosphine oxide groups
positively affected the chemical and stereochemical
catalytic efficiency of these ligands. The new catalysts
were able to promote the allylation of aldehydes with
allyltrichlorosilane in up to 76% yield and up to 86%
enantiomeric excess (ee), and the direct aldol reaction to
afford β-hydroxy ketones in high diastereoselectivity (up
to 88:12 anti:syn ratio) and up to 72% ee.
Acute uterine rupture in spontaneous term labour in a healthy primigravida: case report and review of the literature
Authors: Omih Edwin , Dwyer James 
Published: June 2015

Abstract
Uterine rupture is an obstetric complication with potential catastrophic fetal and maternal consequences, if not detected early and managed promptly. We report a case of a 32-year-old primigravida in spontaneous labour at term who had unprovoked acute uterine rupture. Operative findings at emergency caesarean section were a live female infant weighing 3150 g requiring resuscitation, massive haemoperitoneum, and large right vertical posterolateral uterine rupture at the upper segment, extending to the ovarian pedicle and down to the vagina vault.
Kinetics of ion flotation of Co(II)–EDTA complexes from aqueous solutions
Authors: Soliman Mohamed A. , Rashad Ghada M. , Mahmoud Mamdoh R. 
Published: June 2015

Abstract
The flotation kinetics of Co(II)-EDTA complexes from aqueous solutions using cetylpyridinium chloride (CPyCl) is studied and discussed
in the present work. The effects of many variables on the ultimate recovery and the flotation rate are investigated. The data obtained
from solutions of different pH values showed that Co(II)-EDTA complexes are successfully floated at pH 7.8. While at pH 3.4 and
11.2, both the ultimate recovery and the flotation rate are dependent on the concentration of CPyCl. Flotation of Co(II)-EDTA at
different air flow rates, CPyCl concentrations and ionic strength showed that the ultimate recovery and the flotation rate are markedly
affected. The other parameters (cobalt, EDTA and ethanol concentrations) had no effect on the ultimate recovery, while significantly
affected the flotation rate. At the optimum conditions (Co(II) : EDTA = 1:1; CPyCl : Co(II) = 4:1; pH7.8;
G = 25 cm3/min), removals more than 99% are achieved for radiocobalt. The classical first-order and the
second-order kinetic models are used throughout the work to analyze the experimental kinetic data. At all the studied parameters, the
kinetic data of Co(II)-EDTA complexes are better fitted to the classical first-order model.
Determination of the 151Sm half-life
Authors: Bé Marie-Martine , Isnard Hélène , Cassette Philippe , Mougeot Xavier , Lourenço Valérie , Altzitzoglou Timotheos , Pommé Stefaan , Rožkov Andrej , Auerbach Pavel , Sochorová Jana , Dziel Tomasz , Dersch Rainer , Kossert Karsten , Nähle Ole , Krivošík Matej , Ometáková Jarmila , Stadelmann Guillaume , Nonell Anthony , Chartier Frédéric 
Published: June 2015

Abstract
New measurements have been undertaken to determine the half-life of 151Sm. A pure 151Sm solution was obtained
after chemical separation from a samarium solution resulting from the dissolution of an irradiated samarium sample. The concentration
of 151Sm in the solution was measured by mass spectrometry, combined with the isotope dilution technique. The activity of
the solution was measured by liquid scintillation counting by six European laboratories as part of an international comparison. These
combined results lead to a half-life of T
1/2 = 94.6(6) a.
The isolation and characterisation of the synthetic cannabinoid AM-2201 from commercial products using purification by HPLC-DAD
Authors: Duranovic Smilja , Elie Mathieu , Baron Mark 
Published: June 2015

AbstractA total of six products containing legal highs were purchased via the internet from the UK- based retailers and screened for the presence of synthetic cannabinoids using a fast GC-MS method and identified, in the absence of reference materials, by comparing the mass spectra with the Scientific Working Group for the Analysis of Seized Drugs (SWGDRUG) mass spectral library. Four synthetic cannabinoids were detected: RCS-4, CP-47, 497, UR-144 and AM-2201. The active ingredient (1-(5-fluoropentyl)-3-(1-naphthoyl) indole), with the street name AM-2201, detected in the product named Doob was isolated and purified from the methanolic extract of the product using preparative HPLC with analytical column (column overloading method). The structure of the substance was confirmed using NMR. This approach used common analytical equipment found in forensic and other analytical laboratories (except for the NMR), therefore can be useful for the identification of unknown psychoactive substances in drugs of abuse.
ACADEMIA DE FÍSICA EN MÉXICO VERSUS INVESTIGACIÓN MUNDIAL
Authors: Campuzano Cuauhtemoc 
Published: June 2015

<p>El presente trabajo es una revisión de la conformación de la Academia de Física en México, tomando una pequeña muestra de lo que es el establecimiento de algunas de las más importantes. Definitivamente es una muestra representativa de la dirección actual de la investigación en física. Además, se presentan argumentos de la crisis en que la investigación en México está ocurriendo, signo reflejo de la crisis mundial en este momento.</p>
Reading Under the ESP Approach
Authors: De Guerrero Nery Yolanda Ruiz , Arias Gladis Leonor 
Published: June 2015

<p>This paper contains the theoretical support necessary to develop the project “Reading as a pedagogical resource in specific areas”. The purpose is to implement reading under the parameters of ESP (English for Specific Purposes) through the communicative approach, at USTA (Universidad Santo Tomás, Tunja), with a group of students of V level of English, who read topics of their<br />own field of study; acquiring specific vocabulary and information as well as improving in the use of English as a foreign language, work which is verified by researchers through oral and written practice.</p>
Redes académicas y producción de conocimiento pertinente
Authors: Villamarín Maria Gaby Boshell 
Published: June 2015

<p class="Default"> Las redes académicas se posicionan cada vez más en la educación superior, articulando instituciones de diferente naturaleza tanto del orden nacional como internacional para la producción del co­nocimiento. La emergencia de estas redes ha generado interro­gantes y necesidades para la gestión curricular. Con el propósito de contribuir en este campo de reflexión, en este artículo se sitúa al lector en los antecedentes de las redes y luego se abordan el modo 2 y el de la triple hélice como referentes para la producción de conocimiento en red. A partir de estos modelos se analiza y desarrolla, al mismo tiempo, una propuesta para la construcción de conocimiento pertinente en red.</p>
La escritura en danza, un ruego del cuerpo. El caso del tango-danza en Colombia
Authors: Salazar Ospina Matilde 
Published: June 2015

El conocimiento, procesos de transformación, memoria colectiva<br />y herencia cultural que se centra en la danza son procesos<br />de creación cuya búsqueda se gesta en el dominio técnico de<br />lo corporal, pero no se consolidan en formatos que permitan<br />la transmisión, herencia y reguardo de este saber corporal. Tomando como punto de partida los resultados de entrevistas a diferentes académicos y artistas escénicos de Bogotá, realizadas en la segunda parte del proyecto de investigación Caracterización de la institucionalización y formalización de los procesos de investigación-creación artística en Colombia. Se encontró que la gran producción académica de investigación en danza la realizan profesionales de pedagogía, historia, antropología y filosofía, a la vez que los creadores de la ejecución práctica de danza, se distancian de este tipo de producción escrita. Este panorama nos abre la discusión a lo que García Canclini llama el rescate de la cultura desconocida, el cuerpo sin memoria y sin huella. Entonces, analizando los posibles panoramas de conjunción entre teoría y la creación en danza se revisarán las construcciones académicas que se pueden gestar para la construcción de un puente que dé unidad de sentido a ambas esferas del conocimiento;analizando un caso histórico donde la escritura en danza, la escritura de sus procesos de creación y consolidación fue la base para poder transmitir el conocimiento de una de las<br />técnicas en danza más reconocidas en la actualidad, el tango-danza.
Experiencia estética de la naturaleza y concepción de progreso en la Comisión Corográfica
Authors: Vega Mario Alejandro Molano 
Published: June 2015

<p>El artículo de reflexión plantea la exploración de dos temáticas que se entrelazan en la modernidad cultural y artística: la experiencia estética de la naturaleza y la comprensión de la temporalidad en términos de progreso. En la historia cultural de Colombia este entrelazamiento resulta evidente en el caso de estudio de la Comisión Corográfica. Este ha sido considerado el proyecto científico y cultural más ambicioso del siglo xix. Fue concebido dentro de un espíritu de reformismo liberal y agrupó intelectuales, científicos y artistas de gran importancia, como Manuel Acízar, Agustín Codazzi y Carmelo Fernández, entre otros. Para analizar las temáticas planteadas se empleará la perspectiva de investigación formulada por Hans-Robert Jauss en términos de una <em>historia de las </em><em>formas de experiencia estética</em>. Esta perspectiva permite preguntarse por el surgimiento histórico de diversas formas de la praxis artística y de la apreciación estética del mundo; adicionalmente, permite plantear la relación que existe en cada caso entre las formas de experiencia estética y los procesos políticos de la modernidad. El artículo se detiene particularmente en las figuras de Alexander von Humboldt y Agustín Codazzi para analizar la concepción de la naturaleza y del progreso en la cual se apoyan y que determinó en buena medida la perspectiva de la Comisión Corográfica.</p>
El lenguaje de las cosas desconocidas: tríptico de la cuestión
Authors: Rodríguez Juan Sebastián Ballén 
Published: June 2015

<p>En la historia de la antropología filosófica ninguna otra cuestión ha dimensionado el carácter problemático y paradójico que se desprende de la cuestión acerca de lo que significa ser hombre. Las líneas de fuga que aquí se proponen, son lecturas complementarias a las formuladas por la tradición metafísica (Aristóteles, Santo Tomás y Heidegger), estructuralista (Levi-Strauss y Foucault) y cultural (Protágoras de Abdera y Nietzsche). Se inscribe en la tradición de la filosofía trascendental, pero acentuando el énfasis en una obra poco explorada desde una mirada antropológica, y la cual parte originariamente de una preocupación estética. La tercera crítica kantiana es el “caldo de cultivo” sobre el cual se proyectarán las bases de un apuesta teórica que he denominado <em>antropología simbólica</em>, propuesta cuya caja de resonancia evocará la tradición de la <em>Antropología filosófica. Introducción a </em><em>una Filosofía de la cultura </em>(1944) del neokantiano Ernst Cassirer, y desde Latinoamérica, en una perspectiva actual, con las investigaciones adelantadas por el filósofo mexicano Mauricio Beuchot, particularmente su provocadora propuesta de una hermenéutica analógica, y que en este primer estudio será valorada a partir de un libro diciente y profundo titulado <em>Hermenéutica, analogía y símbolo </em>(2004).</p>