bluuebunny/crossref_metadata_2025_split huggingface dataset:
circlizeimplements and enhances circular visualization in R
Authors: Gu Zuguang , Gu Lei , Eils Roland , Schlesner Matthias , Brors Benedikt 
Published: June 2014

AbstractSummary: Circular layout is an efficient way for the visualization of huge amounts of genomic information. Here we present the circlize package, which provides an implementation of circular layout generation in R as well as an enhancement of available software. The flexibility of this package is based on the usage of low-level graphics functions such that self-defined high-level graphics can be easily implemented by users for specific purposes. Together with the seamless connection between the powerful computational and visual environment in R, circlize gives users more convenience and freedom to design figures for better understanding genomic patterns behind multi-dimensional data.Availability and implementation: circlize is available at the Comprehensive R Archive Network (CRAN): http://cran.r-project.org/web/packages/circlize/Contact: b.brors@dkfz.deSupplementary information: Supplementary data are available at Bioinformatics online.
Possible influence of salmon farming on long-term resident behaviour of wild saithe (Pollachius virens L.)
Authors: Otterå Håkon , Skilbrei Ove T. 
Published: June 2014

Abstract
The culture of Atlantic salmon is one of the most developed aquaculture industries in the world. The production from smolt to market size usually takes place in sea cages in open waters, and these structures tend to attract wild fish, as they do for other farmed species. For salmon farming, saithe (Pollachius virens) is one of the most-frequently observed species around sea cages. An important question is whether the large concentration of salmon farms in some areas might alter the natural behaviour and migration pattern of wild saithe. We tagged 62 wild saithe with acoustic tags and followed their movements for up to 2 years in an area in Southwestern Norway with many salmon farms. Furthermore, nearly 2000 saithe were tagged with external T-bar tags to study migration beyond the study area. The recaptures of the T-bar tagged saithe from offshore areas suggest that the offshore migration routes of saithe are similar to published results from before salmon farming became significant in the area. However, a large proportion of the saithe population appears to remain in the release area and was observed at the salmon farms for much of the time. We conclude that the aquaculture industry is influencing the local saithe distribution. Large-scale population effects are more difficult to prove, but it is possible that the dynamic relationship between the coastal and oceanic phases has been altered.
Establishment of regions of genomic activity during theDrosophilamaternal to zygotic transition
Authors: Li Xiao-Yong , Harrison Melissa M. , Kaplan Tommy , Eisen Michael B. 
Published: June 2014

AbstractA conspicuous feature of early animal development is the lack of transcription from the embryonic genome, and it typically takes several hours to several days (depending on the species) until widespread transcription of the embryonic genome begins. Although this transition is ubiquitous, relatively little is known about how the shift from a transcriptionally quiescent to transcriptionally active genome is controlled. We describe here the genome-wide distributions and temporal dynamics of nucleosomes and post-translational histone modifications through the maternal-to-zygotic transition in embryos of the pomace flyDrosophila melanogaster. At mitotic cycle 8, when few zygotic genes are being transcribed, embryonic chromatin is in a relatively simple state: there are few nucleosome free regions, undetectable levels of the histone methylation marks characteristic of mature chromatin, and low levels of histone acetylation at a relatively small number of loci. Histone acetylation increases by cycle 11, but it is not until cycle 13 that nucleosome free regions and domains of histone methylation become widespread. Early histone acetylation is strongly associated with regions that we have previously shown are bound in early embryos by the maternally deposited transcription factor Zelda. Most of these Zelda-bound regions are destined to be enhancers or promoters active during mitotic cycle 14, and our data demonstrate that they are biochemically distinct long before they become active, raising the possibility that Zelda triggers a cascade of events, including the accumulation of specific histone modifications, that plays a role in the subsequent activation of these sequences. Many of these Zelda-associated active regions occur in larger domains that we find strongly enriched for histone marks characteristic of Polycomb-mediated repression, suggesting a dynamic balance between Zelda activation and Polycomb repression. Collectively, these data paint a complex picture of a genome in transition from a quiescent to an active state, and highlight the role of Zelda in mediating this transition.
The development of cultural entrepreneurship
Authors: Cheung Leung Chi 
Published: June 2014

Purpose
– The aim of the study is to examine the development of four not-for-profit Chinese orchestras in Hong Kong, aiming to identify their key characteristics in management and operational practices, and highlight a probable proposal on how the concept of cultural entrepreneurship could be brought about for the growth of an orchestra.

Design/methodology/approach
– This study looks into the cases of the development of four not-for-profit community Chinese orchestras in Hong Kong in accordance to the theoretical framework built on the reviewed literature. A self-assessment questionnaire survey was conducted among the key leaders in the orchestras, asking them to evaluate themselves about their features as a cultural entrepreneur, and the extent of the development of the orchestras towards entrepreneurship. The survey serves as preliminary reference data for follow-up phone interviews, with questions asked in accordance to the results of the survey.

Findings
– The study shows that the four leaders of the Chinese orchestras have different qualities of a cultural entrepreneur. The four orchestras use different strategies to promote Chinese music, and adopt diversified approaches to survive. Four models of community orchestra having different features are identified, namely new generation model, affiliation-based model, mentor-mentee model, and developmental model. The findings suggest that community orchestras have limitations to the development of cultural entrepreneurship in Hong Kong, and they need the support of the right person and policy to grow and foster.

Originality/value
– The results inform and give insights to cultural entrepreneur-to-bes and practitioners in the cultural industries as well as policy makers on some of the probable innovations employed by not-for-profit community performing groups.
Consumers’ beliefs, attitudes, and loyalty in purchasing organic foods
Authors: Lee Hyun-Joo , Goudeau Cynthia 
Published: June 2014

Purpose
– The purpose of this paper is to apply the standard learning hierarchy to the study of organic foods. More specifically, this research is intended to examine if cognition in the form of beliefs and utilitarian attitudes, affect in the form of hedonic attitudes, and behavior in the form of attitudinal loyalty and behavioral loyalty occur successively.

Design/methodology/approach
– A total of 725 consumer panel data were obtained through a web-based survey. A two-stage structural equation modeling with AMOS graphics version 18.0 was used to validate the measurement models and test the proposed hypotheses.

Findings
– While health benefits positively influenced utilitarian attitudes, no significant effect of ecological welfare benefits was detected. The results also indicate that utilitarian attitudes had a significant and positive relationship with hedonic attitudes, which in turn led to attitudinal loyalty. Lastly, the relation between attitudinal loyalty and behavioral loyalty was significant and positive.

Research limitations/implications
– Global attitudes and loyalty toward organic foods were examined in this research. Thus, future research could investigate more domain-specific attitudes and loyalty to various organic food items.

Practical implications
– The development of positive attitudes toward organic foods among consumers is important for the long-term success of organic food products or brands.

Originality/value
– There is a little research that adopts an established theory or theoretical approach to explain a purchase behavior of organic foods. For this reason, the standard learning hierarchy was incorporated in order to study how cognition, affect, and behavior are formed when a purchase decision involving organic foods.
Disentangling direct and indirect effects of credence labels
Authors: Dentoni Domenico , T. Tonsor Glynn , Calantone Roger , Christopher Peterson H. 
Published: June 2014

Purpose
– The purpose of this paper is to disentangle the direct and indirect effects of three credence labels (Australian, animal welfare and grass-fed) on US consumer attitudes toward buying beef steaks. Furthermore, it explores the impact of consumer attribute knowledge, usage frequency, education and opinion strength on the magnitude of direct and indirect effects.

Design/methodology/approach
– Data are collected through an online experiment with 460 US consumers and analyzed with path modeling.

Findings
– The Australian label generates a 86 percent negative direct effect vs a 14 percent negative indirect effect on consumer attitudes, which means that US consumers do not make strong inferences to form their attitudes toward buying Australian beef. The animal welfare label generates 50 percent direct and 50 percent indirect effects. The grass-fed label generates only indirect effects (100 percent). The higher consumer education, attribute knowledge, usage frequency, education and opinion strength, the weaker are the indirect effects of credence labels.

Research limitations/implications
– The study focusses on consumers in one country (USA), one product (beef steak) and one label across three attributes, therefore generalization of results is limited.

Practical implications
– The study offers a tool to agribusiness managers as well as to policy makers, NGOs and consumer groups to design and assess the effectiveness of communication campaigns attempting to strengthen (or weaken) consumer inferences and attitudes relative to credence labels.

Originality/value
– Despite the wide literature on consumer inferences based on credence labels, this is the first study that quantitatively disentangles the complex set of inferential effects generated by credence labels and explores common relationships across multiple credence attributes.
Parental risk perception of mycotoxins and risk reduction behaviour
Authors: Niens Christine , Strack Micha , Marggraf Rainer 
Published: June 2014

Purpose
– The purpose of this paper is to analyse the parental risk perception of mycotoxins (mould toxins) related to child health in Germany. It ascertains the parental risk reduction behaviour operationalised as parental additional willingness to pay (aWTP) for special child products. It investigates the interrelationships between parental risk perceptions and risk reduction behaviour.

Design/methodology/approach
– Altogether, 771 questionnaires were sent to 17 day-care centres in Lower Saxony, Germany. A total of 238 questionnaires were completed. The Perceived Food Risk Index was used to identify the main dimensions of parental risk perception of mycotoxins. Open and closed questions measured aWTP for risk reduction and parental risk estimates.

Findings
– The respondents believed that mycotoxins posed a moderate health risk for children in Germany. However, parental risk assessment was found to be subjected to an optimistic bias. Nevertheless, the parents were willing to pay a premium to protect their children's health against mycotoxins. Parental risk perception of mycotoxins could be described by two dimensions named “Dread” and “Control”. “Dread” and “Control” predicted aWTP for risk reduction as well as being involved in the genesis of optimistic bias.

Research limitations/implications
– Information regarding mycotoxins provided in the questionnaire probably influenced parental responses. This limits the generalisation of the findings.

Originality/value
– This research provides initial findings regarding parental risk perceptions of mycotoxins and its impact on risk reduction behaviour. The results are useful for the development of effective risk management and thus for the protection of child health.
Exploring comparative efficiency and determinants of efficiency for major world airlines
Authors: Joo Seong-Jong , L. Fowler Karen 
Published: June 2014

Purpose– For strategic and competitive insights, this paper aims to measure and benchmark comparative operating efficiencies of major airlines in Asia, Europe, and North America.Design/methodology/approach– The authors employ data envelopment analysis for measuring the relative efficiency of 90 airlines in Asia, Europe, and North America. In addition, the authors use Tobit regression analysis for finding determinants of the efficiency.Findings– Results indicate that the efficiency of the airlines in Europe is the lowest among the airlines in these three regions. Efficiency differences between the airlines in Europe and the airlines in the two other regions (Asia and North America) are statistically significant in terms of technical efficiency and pure technical efficiency, but not significant between the airlines in Asia and North America. For the determinants of efficiency, the authors identified that revenues and expenses were significant for explaining efficiency scores of airlines.Research limitations/implications– Further research is needed to explain the findings that airlines in Europe were less efficient than airlines in Asia and North America. In addition, including variables on customer satisfaction in a future study is desirable.Originality/value– Major contributions of this study include measuring the comparative efficiency of major airlines in Asia, Europe, and North America and finding determinants of the efficiency for strategic insights.
Implicit memory-based technique in solving dynamic scheduling problems through Response Surface Methodology – Part II
Authors: Blanco Abello Manuel , Michalewicz Zbigniew 
Published: June 2014

Purpose
– This is the second part of a two-part paper. The purpose of this paper is to report the results on the application of the methods that use the Response Surface Methodology to investigate an evolutionary algorithm (EA) and memory-based approach referred to as McBAR – the Mapping of Task IDs for Centroid-Based Adaptation with Random Immigrants.

Design/methodology/approach
– The methods applied in this paper are fully explained in the first part. They are utilized to investigate the performances (ability to determine solutions to problems) of techniques composed of McBAR and some EA-based techniques for solving some multi-objective dynamic resource-constrained project scheduling problems with a variable number of tasks.

Findings
– The main results include the following: first, some algorithmic components of McBAR are legitimate; second, the performance of McBAR is generally superior to those of the other techniques after increase in the number of tasks in each of the above-mentioned problems; and third, McBAR has the most resilient performance among the techniques against changes in the environment that set the problems.

Originality/value
– This paper is novel for investigating the enumerated results.
Aged care, cultural and linguistic diversity and IT in Australia: a critical perspective
Authors: O’Mara Ben 
Published: June 2014

Purpose
– The purpose of this paper is to contribute a critical perspective to debate on health disparities in Australia by examining the ways in which information technology (IT) can support more inclusive communication on aged care with refugee and migrant communities from culturally and linguistically diverse (CALD) backgrounds.

Design/methodology/approach
– The paper analyses research and policy literature on Australian aged care, IT and participatory approaches to health communication influenced by Friere's critical pedagogy. It distils significant themes for comparison with findings from: a qualitative research project involving communities from Vietnamese, Sudanese and Samoan backgrounds and elderly members of those groups; and, a later case study conducted with elderly women of Vietnamese background. Both projects were based in Melbourne's west.

Findings
– Friere's theoretical framework can be used to more fully determine the capacity of IT to perform inclusive communication on aged care with refugee and migrant communities from CALD backgrounds. This is best actioned through future research and practice that: prioritizes specific aged care issues; focuses on expanding the “transformation” and “critical consciousness” elements of Friere's dialogical theory; and, uses affordable, accessible and “multi-modal” IT combined with face-to-face bilingual facilitation and two-way communication between participants and health, community and university professionals.

Research limitations/implications
– Due to the conceptual nature of the paper, the research results lack generalizability. Therefore, researchers are encouraged to test the reccomendations further.

Originality/value
– The paper fills a gap in understanding about what may help in developing more inclusive aged care information using IT with elderly refugees and migrants from CALD backgrounds in Australia.
Application of Lean Six Sigma methodology in the registration process of a hospital
Authors: Bhat Shreeranga , Gijo E.V. , Jnanesh N.A. 
Published: June 2014

Purpose– The purpose of this paper is to study the scope of Lean Six Sigma (LSS) strategy and to explore its successful deployment in the Indian healthcare sector.Design/methodology/approach– The research reported in this paper is based on a case study carried out using the LSS DMAIC (Define-Measure-Analyze-Control) approach and its application in improving the registration process in the Health Information Department (HID) of a Medical College hospital in India.Findings– The study describes improvements in the HID through the power of LSS. Cycle time of the process was reduced from three to 1.5 minutes and the SD was reduced to 21.2 from 61 seconds. The project has shown a 94 per cent reduction in patients’ average waiting time. The study also reported a 91 per cent reduction in queue length and 48 per cent reduction in percentage of scheduled utilization of staff for the process.Research limitations/implications– The paper is based on a single case study executed in a hospital and hence there is limitation in generalizing the specific results from the study. But the approach adopted and the learning from this study can be generalized. The study is of use to healthcare practitioners seeking to implement or develop LSS further in their organizations.Originality/value– Although LSS being extremely successful in the last two decades, the application of LSS to the healthcare industry in general and HID in particular has been limited. This study illustrates how its application can improve the performance of the process and thus productivity in the department.
Coping with the death of singleton children in China: the role of social capital
Authors: Yan Flora Lau Pui 
Published: June 2014

Purpose– Discussion of China's one-child policy generally centres on its demographic effects. Bereavement among parents of singleton children and the role of social capital in the bereavement process have been under-explored. The purpose of this paper is to focus on mothers who lost their only children during the Sichuan earthquake in 2008. The paper aims to discuss the under-explored yet crucial issues of the one-child policy – the ways in which Chinese bereaved mothers handle the death of their singleton children – and the roles that social capital can play in their bereavement process.Design/methodology/approach– The author conducted eight case studies on bereaved mothers through home visits, semi-structured interviews and participation in public activities during August 2010 and May 2011. In-depth interviews were used to collect information from these bereaved mothers in Sichuan, China.Findings– The case studies reveal two major experiences of bereaved mother whose familial support varies substantially. One major experience is shared by those who had received emotional support from husband (who offered bonding social capital), and were able to get through the psychological pain. Another experience is shared by bereaved mothers who lost their familial relations. Weak social ties (i.e. an NGO which offered bridging social capital) remained the only source of support. Policies can target at the latter group of mothers by helping them to organise themselves into community-based groups and help to relieve their frustration and grief.Originality/value– These research findings have implications for the development of NGOs, as well as complementary support for community-based bereavement counselling and community care in China.
Measuring abnormal pricing – an alternative approach
Authors: Hong Keejae , H. Pak Cabrini , J. Pak Simon 
Published: June 2014

Purpose
– The purpose of this study is to examine the degree of trade mispricing in the US fresh banana trade with Latin American and Caribbean countries using a new alternative measure in estimating arm’s length price.

Design/methodology/approach
– A key feature of the research design is that we use the actual free market price of commodity (e.g. fresh banana price) as a benchmark for arm’s length price rather than relying on interquartile range, which is known to be problematic.

Findings
– The paper finds that when the degree of mispricing is measured by two widely used methods, interquartile price filter and partner-country methods, we find little evidence of undervaluation or overvaluation of US banana import. However, when we use the free-market price of fresh banana as a benchmark for arm’s length price, first adopted in this study, the average undervalued amount of trade compared to the total banana import declared value by the US importers is on average 54 per cent during the period between 2000 and 2009.

Originality/value
– This study suggests a new simple measure in estimating arm’s length traction price in studying trade mispricing.