bluuebunny/crossref_metadata_2025_split huggingface dataset:
Noninvasive evaluation of single-ventricle patients before Fontan operation
Authors: Yassin Haytham , Bhat Akhlaque N , Tysarowski Pawl , Masud Faraz , Dilawar Muhammad 
Published: September 2014

Objective To determine whether patients with single-ventricle physiology who are free from known risk factors could skip routine pre-Fontan hemodynamic evaluation, without affecting the postoperative outcome. Methods A diagnostic algorithm including echocardiographic, clinical, and angiographic risk factors was used retrospectively to evaluate all 44 patients who underwent Fontan completion at Hamad General Hospital between January 2000 and December 2012. We evaluated the efficacy of this algorithm as a screening tool to identify inoperable and high-risk patients in whom pre-Fontan cardiac catheterization should be performed. Results Mean age at Fontan completion was 5.9 years (range 1.08–24.5 years), and mean weight was 18 kg (range 7.4–60 kg). Three patients were found to be inoperable based on hemodynamic cardiac catheterization results. The algorithm was highly sensitive in detecting all 3 inoperable patients who were classified as high-risk subjects. Of the other 41 patients, 17 (41%) had no risk factors and 24 (59%) had one or more risk factors. This noninvasive algorithm showed a sensitivity of 83% and specificity of 76% in detecting adverse postoperative outcomes. The sensitivity did not change after adding hemodynamic data obtained by cardiac catheterization as additional risk factors. Conclusion This noninvasive diagnostic algorithm could be used as an effective screening tool to detect patients in whom pre-Fontan cardiac catheterization could be avoided; magnetic resonance imaging and computed tomography can be a good substitute.
Distinct Effects of Platelet-Rich Plasma and BMP13 on Rotator Cuff Tendon Injury Healing in a Rat Model
Authors: Lamplot Joseph D. , Angeline Michael , Angeles Jovito , Beederman Maureen , Wagner Eric , Rastegar Farbod , Scott Bryan , Skjong Christian , Mass Daniel , Kang Richard , Ho Sherwin , Shi Lewis L. 
Published: September 2014

Background: Although platelet-rich plasma (PRP) is used clinically to augment tendon healing, bone morphogenetic protein–13 (BMP13) may provide a better therapeutic avenue to improve early tendon healing and repair. Hypothesis: Exogenous expression of BMP13 in tenocytes will up-regulate genes involved in tendon healing. Direct delivery of adenovirus-mediated BMP13 (AdBMP13) into the injured rat supraspinatus tendon will increase biomechanical properties. Study Design: Controlled laboratory study. Methods: Exogenous expression of BMP13 and the major growth factors in PRP (transforming growth factor–β1 [TGF-β1], vascular endothelial growth factor–A [VEGF-A], and platelet-derived growth factor–BB [PDGF-BB]) was accomplished by using recombinant adenoviral vectors. The expression of tendon- and matrix-associated genes in growth factor–treated tenocytes was analyzed by use of semiquantitative reverse-transcription polymerase chain reaction. A total of 32 rats with supraspinatus defect were divided into 4 groups and injected with adenovirus-containing green fluorescent protein (AdGFP; negative control), PRP, AdBMP13, or PRP+AdBMP13. All rats were sacrificed at 2 weeks after surgery, and tendons were harvested for biomechanical testing and histologic analysis. Results: BMP13 up-regulated type III collagen expression compared with AdGFP control and PRP growth factors ( P < .01). BMP13 and PRP growth factors each up-regulated fibronectin expression ( P < .01). There was an increase in stress to failure in each of the 3 treatment groups ( P < .05 for PRP; P < .01 for AdBMP13 or PRP+AdBMP13) compared with AdGFP control. AdBMP13 demonstrated higher stress to failure than did the PRPs ( P < .01). The addition of PRP did not increase the BMP13-enhanced stress to failure or stiffness. The biomechanical results were further supported by histologic analysis of the retrieved samples. Conclusion: Exogenous expression of BMP13 enhances tendon healing more effectively than PRP as assessed by tendon- and matrix-associated gene expression, biomechanical testing, and histologic analysis. Clinical Relevance: While PRP is used in the clinical setting, BMP13 may be explored as a superior biofactor to improve rotator cuff tendon healing and reduce the incidence of retears.
Delusion of Pregnancy
Authors: Cipriani Gabriele , Di Fiorino Mario 
Published: September 2014

Background: Delusions can complicate practically all brain disorders. They may be dramatic and bizarre. An example is the so-called delusion of pregnancy. Objective: To identify the characteristic of a psychotic symptom, the phenomenon of delusion of pregnancy, in the context of dementia. Method: MEDLINE and Google Scholar searches were conducted for relevant articles, chapters, and books published before 2014. Search terms used included delusion of pregnancy, uncommon presentation, behavioral and psychological symptoms, dementia, Alzheimer’s disease, and frontotemporal dementia (FTD). Publications found through this indexed search were reviewed for further relevant references. We included case reports that highlight the relationship and overlap between dementia presenting as schizophrenia-like psychosis and schizophrenia. Results: Literature on delusion of pregnancy in the course of dementia consists mostly of case reports and small samples of patients. Conclusion: Psychotic phenomena such as delusion of pregnancy may be a feature in some cases of dementia. If this bizarre features of dementia appears as early presentation of FTD whose usual onset is in the presenium, it may be mistaken for schizophrenia.
A longitudinal study of skin barrier function in pregnancy and the postnatal period
Authors: Gallagher Aine , Hourihane Jonathan O’B , Kenny Louise C , Irvine Alan D , Khashan Ali S 
Published: September 2014

Background It is unknown whether skin’s barrier function changes in pregnancy. Trans Epidermal Water Loss (TEWL) refers to the total amount of water loss through the skin and TEWL can be measured non-invasively as an index of skin barrier function. We measured TEWL during and after pregnancy to evaluate pregnancy-related skin barrier function. Methods This was a prospective, longitudinal cohort study of 52 low-risk, first-time pregnant women nested within the Screening for Pregnancy Endpoints (SCOPE) Ireland study. TEWL (gwater/m2/h) was measured three times during pregnancy: 19–21 weeks, 27–32 weeks and 36 weeks; and three times postnatally: 2–4 days, 2 months and 6 months post-delivery. Data were analysed using SPSS 18.0 and P > 0.05 was considered statistically significant. Results A rise in TEWL was seen between each visit with the highest readings, exceeding the normal range of 0–20 gwater/m2/h, recorded at two months post-delivery. Forty women attended at two months post-delivery of whom 22 women had an average reading between 0 and 20 gwater/m2/h; 10 women had an average reading between 21 and 40 gwater/m2/h and 8 women had an average reading between 41 and 75 gwater/m2/h. Readings had returned to an average of 0–20 gwater/m2/h at six months postnatally. Conclusion TEWL increases slightly in pregnancy and the postnatal period. The clinical significance of this is unclear and requires further investigation.
Iniciativas escolares y deportivas lideradas desde la Fédération Internationale de Football Association (FIFA): revisión sistemática
Authors: Correa Jorge E. , Meneses-Echávez José F. , Barengo Noël C. , Tovar Gustavo , Ruiz-Castellanos Erika , Lobelo Felipe , Ramírez-Vélez Robinson 
Published: September 2014

Introducción: Los programas iniciados por la Fédération Internationale de Football Association (FIFA) consisten en la difusión de mensajes relacionados con el cuidado de la salud y como estrategia de prevención de lesiones deportivas entre los niños y jóvenes. El objetivo de esta revisión sistemática fue resumir los resultados de la implementación de los programas “FIFA 11 para la salud” y “FIFA 11+”. Métodos: Se realizó una búsqueda sistemática en las bases de datos electrónicos de MEDLINE, EMBASE y Scopus, identificando los estudios que evaluaran la implementación de los programas “FIFA 11 para la salud” y “FIFA 11+”, durante los últimos 10 años (1 enero 2003 a 1 diciembre 2013). Resultados: Incluimos 17 estudios. Dos estudios evaluaron la implementación del programa “FIFA 11 para la salud” y encontraron un aumento significativo en el conocimiento de los mensajes de promoción de la salud; 15 estudios evaluaron los efectos del programa “FIFA 11+”, reportando una reducción en el riesgo de lesiones deportivas y mejorías en el rendimiento deportivo. Discusión: Los programas “FIFA 11 para la salud” y “FIFA 11+” han demostrado resultados positivos para la salud, en el ámbito escolar y deportivo. Conclusiones: Dichos programas del FIFA representan una oportunidad para crear hábitos protectores y fomentar modos de vida saludables en niños y jóvenes.
Running Habits of Competitive Runners During Pregnancy and Breastfeeding
Authors: Tenforde Adam S. , Toth Kierann E. S. , Langen Elizabeth , Fredericson Michael , Sainani Kristin L. 
Published: September 2014

Background: Running is a popular sport that may be performed safely during pregnancy. Few studies have characterized running behavior of competitive female runners during pregnancy and breastfeeding. Hypothesis: Women modify their running behavior during pregnancy and breastfeeding. Study Design: Observational, cross-sectional study. Level of evidence: Level 2. Methods: One hundred ten female long-distance runners who ran competitively prior to pregnancy completed an online survey characterizing training attitudes and behaviors during pregnancy and postpartum. Results: Seventy percent of runners ran some time during their pregnancy (or pregnancies), but only 31% ran during their third trimester. On average, women reduced training during pregnancy, including cutting their intensity to about half of their nonpregnant running effort. Only 3.9% reported sustaining a running injury while pregnant. Fewer than one third (29.9%) selected fetal health as a reason to continue running during pregnancy. Of the women who breastfed, 84.1% reported running during breastfeeding. Most felt that running had no effect on their ability to breastfeed. Women who ran during breastfeeding were less likely to report postpartum depression than those who did not run (6.7% vs 23.5%, P = 0.051), but we did not detect the same association of running during pregnancy (6.5% vs 15.2%, P = 0.16). Conclusion: Women runners reported a reduction in total training while pregnant, and few sustained running injuries during pregnancy. The effect of running on postpartum depression was not clear from our findings. Clinical Relevance: We characterized running behaviors during pregnancy and breastfeeding in competitive runners. Most continue to run during pregnancy but reduce total training effort. Top reasons for running during pregnancy were fitness, health, and maintaining routine; the most common reason for not running was not feeling well. Most competitive runners run during breastfeeding with little perceived impact.
JAK2 inhibitors do not affect stem cells present in the spleens of patients with myelofibrosis
Authors: Wang Xiaoli , Ye Fei , Tripodi Joseph , Hu Cing Siang , Qiu Jiajing , Najfeld Vesna , Novak Jesse , Li Yan , Rampal Raajit , Hoffman Ronald 
Published: September 2014

Key Points
JAK2 inhibitors affect more mature MF progenitors, but spare disease-initiating stem cells. Reduction in spleen size achieved with JAK2 inhibitor therapy in MF can be attributed to depletion of a subpopulation of MF progenitors.
Adult lung function and long-term air pollution exposure. ESCAPE: a multicentre cohort study and meta-analysis
Authors: Adam Martin , Schikowski Tamara , Carsin Anne Elie , Cai Yutong , Jacquemin Benedicte , Sanchez Margaux , Vierkötter Andrea , Marcon Alessandro , Keidel Dirk , Sugiri Dorothee , Al Kanani Zaina , Nadif Rachel , Siroux Valérie , Hardy Rebecca , Kuh Diana , Rochat Thierry , Bridevaux Pierre-Olivier , Eeftens Marloes , Tsai Ming-Yi , Villani Simona , Phuleria Harish Chandra , Birk Matthias , Cyrys Josef , Cirach Marta , de Nazelle Audrey , Nieuwenhuijsen Mark J. , Forsberg Bertil , de Hoogh Kees , Declerq Christophe , Bono Roberto , Piccioni Pavilio , Quass Ulrich , Heinrich Joachim , Jarvis Deborah , Pin Isabelle , Beelen Rob , Hoek Gerard , Brunekreef Bert , Schindler Christian , Sunyer Jordi , Krämer Ursula , Kauffmann Francine , Hansell Anna L. , Künzli Nino , Probst-Hensch Nicole 
Published: September 2014

The chronic impact of ambient air pollutants on lung function in adults is not fully understood. The objective of this study was to investigate the association of long-term exposure to ambient air pollution with lung function in adult participants from five cohorts in the European Study of Cohorts for Air Pollution Effects (ESCAPE).Residential exposure to nitrogen oxides (NO2, NOx) and particulate matter (PM) was modelled and traffic indicators were assessed in a standardised manner. The spirometric parameters forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC) from 7613 subjects were considered as outcomes. Cohort-specific results were combined using meta-analysis.We did not observe an association of air pollution with longitudinal change in lung function, but we observed that a 10 μg·m−3increase in NO2exposure was associated with lower levels of FEV1(−14.0 mL, 95% CI −25.8 to −2.1) and FVC (−14.9 mL, 95% CI −28.7 to −1.1). An increase of 10 μg·m−3in PM10, but not other PM metrics (PM2.5, coarse fraction of PM, PM absorbance), was associated with a lower level of FEV1(−44.6 mL, 95% CI −85.4 to −3.8) and FVC (−59.0 mL, 95% CI −112.3 to −5.6). The associations were particularly strong in obese persons.This study adds to the evidence for an adverse association of ambient air pollution with lung function in adults at very low levels in Europe.
Basic life support is effectively taught in groups of three, five and eight medical students: a prospective, randomized study
Authors: Mahling Moritz , Münch Alexander , Schenk Sebastian , Volkert Stephan , Rein Andreas , Teichner Uwe , Piontek Pascal , Haffner Leopold , Heine Daniel , Manger Andreas , Reutershan Jörg , Rosenberger Peter , Herrmann-Werner Anne , Zipfel Stephan , Celebi Nora 
Published: September 2014

Abstract

Background
Resuscitation is a life-saving measure usually instructed in simulation sessions. Small-group teaching is effective. However, feasible group sizes for resuscitation classes are unknown. We investigated the impact of different group sizes on the outcome of resuscitation training.

Methods
Medical students (n = 74) were randomized to courses with three, five or eight participants per tutor. The course duration was adjusted according to the group size, so that there was a time slot of 6 minutes hands-on time for every student. All participants performed an objective structured clinical examination before and after training. The teaching sessions were videotaped and resuscitation quality was scored using a checklist while we measured the chest compression parameters with a manikin. In addition, we recorded hands-on-time, questions to the tutor and unrelated conversation.

Results
Results are displayed as median (IQR). Checklist pass rates and scores were comparable between the groups of three, five and eight students per tutor in the post-test (93%, 100% and 100%). Groups of eight students asked fewer questions (0.5 (0.0 – 1.0) vs. 3.0 (2.0 – 4.0), p < .001), had less hands-on time (2:16 min (1:15 – 4:55 min) vs. 4:07 min (2:54 – 5:52 min), p = .02), conducted more unrelated conversations (17.0 ± 5.1 and 2.9 ± 1.7, p < 0.001) and had lower self-assessments than groups of three students per tutor (7.0 (6.1 – 9.0) and 8.2 (7.2 – 9.0), p = .03).

Conclusions
Resuscitation checklist scores and pass rates after training were comparable in groups of three, five or eight medical students, although smaller groups had advantages in teaching interventions and hands-on time. Our results suggest that teaching BLS skills is effective in groups up to eight medical students, but smaller groups yielded more intense teaching conditions, which might be crucial for more complex skills or less advanced students.
Effect of roasting conditions on color development and Fourier transform infrared spectroscopy (FTIR-ATR) analysis of Malaysian-grown tropical almond nuts (Terminalia catappa L.)
Authors: Ng Siewsee , Lasekan Ola , Muhammad Kharidah , Sulaiman Rabiha , Hussain Norhayati 
Published: September 2014

Abstract

Background
Proper roasting is crucial to flavor, color, and texture development in the final product. In recent years, several research studies have been carried out to establish the best optimum roasting conditions for some common edible nuts such as; hazelnut, peanut, and pistachio nut. Although roasting is an important process for nuts and oilseeds, there is little or no information on the development of color, aroma, and textural changes in Terminalia catappa nuts during roasting.

Results
Results showed that color formation and browning index were significantly (P < 0.05) influenced by the roasting temperature and time of roasting. However, the fracturability of nuts was significantly (P < 0.05) affected by both temperature of roasting and time as well as pH. The optimized results showed that the best response was reached when the roasting time was 29.9 min, roasting temperature 174.5°C, and pH 6.08, respectively. Moreover, the 3400–15603400–1560°Cm-1 carbonyl region for carboxylic acid, alkenes, esters, and amines was found to provide a flavor-print of the roasted tropical almond nut. While, increase in temperature did not produce new carbonyl compounds, it however led to higher concentration of compounds. Scanning electron microscopy of the almond nuts showed that the starch granules were embedded in tissues.

Conclusion
These results showed that roasting temperature and time of roasting were the main variables that significantly affected the physicochemical properties of roasted tropical almond nuts. Moreover the flavor-prints for the roasted nut were produced in the 3400–1560°Cm-1 carbonyl region.
O komiksowych panelach translacyjnych, czyli tłumaczenie ustne inaczej
Authors: Jankowski Jakub 
Published: September 2014

About comic book translation sessions or oral translation in a different way
Oral translation can have many faces, mutations and varieties. Some of them may spring out from putting some texts into a new environment. What will happen to the comics if they are forced to speak with the voice of the very one who translated them? What will become of the units which give to the comics the form that we know? How the situation between the emissor and receptor can change while experiencing that kind of audio‑comics? Moreover, is it so that only comics can find themselves in such situation? These problems can be found in the article entitled About comic book translation sessions or oral translation in a different way. We try to prove that border oral translations can be starting points towards brave new areas of scientific interest in the oral translation field.
„Solidarność” i opozycja demokratyczna PRL w latach 1982-1988 a problem realizmu politycznego
Authors: Olaszek Jan 
Published: September 2014

“Solidarity” and the democratic opposition in the Polish People’s Republic in 1982‑1988 and the problem of political realism
How a realist oppositionist could keep being during the martial law? He could not accept the actions of the authorities, because it would mean giving up their ideological identity. The political realism of oppositionist must lead to demands of cancellation of martial law and stop the repression. “Solidarity” during the martial law sustained idealistic goals: program of “Autonomous Republic” and in the future democratic and independent state. Realism method consisted of choosing forms of action that can be used with success. It can be said that a realistic attitude was Lech Walesa in internment, which relied on government inducements to support the martial law, and while there he didn’t give radical slogans and tried to make a realistic political action. Similarly, you can define the actions of leaders of underground “Solidarity”. They are generally approached from a distance to the ideas of a general strike, considering it is not unrealistic, but rather a legitimate considering the concept of the underground society and the long march. In terms of the discussion on political realism, you can also look at the main debate within the “Solidarity” in the second half of the 80th: for making public action and the pursuit of compromise. In conclusion we can say that all the time since martial law opposition was balanced between idealism and realism.
Dialog Cerkwi z państwem w nauce społecznej Patriarchatu Moskiewskiego
Authors: Janowiec Daria 
Published: September 2014

The dialogue between The Orthodox Church and the state in view of the social concept of the Moscow Patriarchate
This paper concerns the issue of the dialog between the Russian Orthodoxy and the state based on the document The Basis of the Social Concept. The main idea is to present a vision of the relationship and cooperation between the Moscow Patriarchate and the state, which was contained in the social concept of the Russian Orthodox Church, as also the impact of this concept on the development of church‑ state relations at the present stage. This issue became the subject of the interest both, researchers, representatives of the Moscow Patriarchate and public opinion as well. Thus, the analysis of this phenomenon is the matter of a great importance to the understanding the nature of the relations between the Orthodox Church and the state in Russia after 1991. The subject of considerations will be such issues like: attitudes to the state and government, the problem of the state system, Christian’s loyalty to the secular national power, concept of the secular state based on the social concept of the Orthodox Church.
Investigación: La inflación argentina actual: Un análisis sobre dos propuestas de política
Authors: Gastaldi Santiago , Arri Noelia Vanina 
Published: September 2014

El presente trabajo, que constituye una primera etapa de una investigación más amplia sobre la inflación en la Argentina reciente, tiene como objetivo analizar los fundamentos teóricos y empíricos de dos propuestas de política económica para detener la inflación argentina actual: por un lado las medidas implementadas por el gobierno, por el otro las recomendaciones de analistas económicos no oficialistas. La motivación del trabajo es la preocupante evolución de la inflación en la Argentina en los últimos 7 años. El marco teórico para esta actividad de investigación es la teoría de la inflación. La hipótesis es que las políticas puestas en ejecución no tienen en cuenta los riesgos inflacionarios de la creación de dinero base a altas tasas. Respecto a la metodología utilizada, en primer lugar se hace una revisión de las principales teorías económicas de la inflación. Luego, se presentan los argumentos del gobierno y de analistas económicos no oficialistas acerca de las causas de la inflación actual y las políticas más apropiadas a implementar para frenarla. En tercer término, considerándose la inflación de demanda en su versión monetarista, la inflación de costos y la inflación estructural las más relevantes para el objetivo propuesto, con datos de variables claves se analiza la consistencia y sustentabilidad de los argumentos de ambas posturas. Los resultados de la investigación avalan —en la interpretación de los autores— la posición de los analistas críticos frente a la posición de los hacedores de política económica.