bluuebunny/crossref_metadata_2025_split huggingface dataset:
Metabolic profiling and combined therapeutic strategies unveil the cytotoxic potential of selenium-chrysin (SeChry) in NSCLC cells
Authors: Mendes Cindy , Lemos Isabel , Hipólito Ana , Abreu Bruna , Freitas-Dias Catarina , Martins Filipa , Pires Rita F. , Barros Hélio , Bonifácio Vasco D.B. , Gonçalves Luís G. , Serpa Jacinta 
Published: July 2024

Abstract
Lung cancer ranks as the predominant cause of cancer-related mortalities on a global scale. Despite progress in therapeutic interventions, encompassing surgical procedures, radiation, chemotherapy, targeted therapies and immunotherapy, the overall prognosis remains unfavorable. Imbalances in redox equilibrium and disrupted redox signaling, common traits in tumors, play crucial roles in malignant progression and treatment resistance. Cancer cells, often characterized by persistent high levels of reactive oxygen species (ROS) resulting from genetic, metabolic, and microenvironmental alterations, counterbalance this by enhancing their antioxidant capacity. Cysteine availability emerges as a critical factor in chemoresistance, shaping the survival dynamics of non-small cell lung cancer (NSCLC) cells. Selenium-chrysin (SeChry) was disclosed as a modulator of cysteine intracellular availability. This study comprehensively characterizes the metabolism of SeChry and investigates its cytotoxic effects in NSCLC. SeChry treatment induces notable metabolic shifts, particularly in selenocompound metabolism, impacting crucial pathways such as glycolysis, gluconeogenesis, the tricarboxylic acid (TCA) cycle, and amino acid metabolism. Additionally, SeChry affects the levels of key metabolites such as acetate, lactate, glucose, and amino acids, contributing to disruptions in redox homeostasis and cellular biosynthesis. The combination of SeChry with other treatments, such as glycolysis inhibition and chemotherapy, results in greater efficacy. Furthermore, by exploiting NSCLC's capacity to consume lactate, the use of lactic acid-conjugated dendrimer nanoparticles for SeChry delivery is investigated, showing specificity to cancer cells expressing monocarboxylate transporters.
Impact of Delta Troponin on Short-Term Mortality in Patients with Chronic Renal Dysfunction and NSTEMI
Authors: Acem Burak , Eroğlu Serkan Emre , Özdemir Serdar 
Published: July 2024

Abstract
Introduction The relationship between mortality and troponin in non-ST-elevation myocardial infarction (NSTEMI) patients with a history of renal failure is quite limited. This study investigated the relationship between blood delta troponin T levels and 30-day mortality in patients with chronic renal dysfunction and NSTEMI.
Materials and Methods This study was conducted prospectively by including patients with chronic renal dysfunction and clinical findings of NSTEMI between February 1, 2021, and August 1, 2022. Demographics, medical history, laboratory parameters, and mortality data were noted. Thirty-day morbidity data was used for mortality. Delta troponin T was calculated using initial and first-hour troponin T values. Patients were grouped as healthy and deceased. Data were evaluated using univariant analysis and receiver operating characteristics analysis.
Results Of the 73 patients included in the study, 29 were female. The mean age of the patients was 67.3 years. The 30-day mortality rate was 9.5%. The sensitivity of the initial troponin T value was 85.7% (42.1–99.6), the specificity was 68.2% (55.6–79.1), and the accuracy was 69.9% (58–80.1), and the sensitivity of the first-hour troponin T value was 85.7% (42.1–99.6), specificity was 75.8% (63.6–85.5), and accuracy was 76.7% (65.4–85.8). The delta troponin T median of the mortality group was 56 (24.2–286.4), and the delta troponin median of the surviving patients was 29.4 (10.7–79.6). The difference was not statistically significant (p = 0.072).
Conclusion The current study's results show that delta troponin T (initial and first hour) is not associated with short-term mortality in patients with chronic renal dysfunction and NSTEMI.
Major Delay in Door-to-Ballon Time for Primary Percutaneous Coronary Intervention is Not Related to Interventional Cardiologist's Late Arrival
Authors: Movahed Mohammad R. , Irilouzadian Rana 
Published: July 2024

AbstractInterventional cardiologists are held accountable for delay in the door-to-balloon time (DBT) for patients undergoing primary percutaneous coronary intervention in the setting of ST-elevation myocardial infarction (STEMI) even though in the chain of STEMI activation, the interventional cardiologist is the last person that needs to be available to start angiography. The goal of our study is to conduct a thorough analysis of the DBT data to assess time delays by randomly evaluating two consecutive years at the University of Arizona Medical Center (UAMC). We evaluated all available DBT data for STEMIs occurring in the fiscal years of 2011 and 2012 at the UAMC and calculated the time needed for the cardiologist to start the procedure after the patient was ready in the cardiac catheterization laboratory called time to start the procedure (TSP) in addition to other time intervals. Mean TSP time was 4 minutes and 24 seconds, one of the shortest time delays in the chain of STEMI activation and DBT. The median TSP delay was 3 minutes. The longest delay interval was the STEMI team's arrival to with a mean of 17 minutes and 38 seconds. Our data are the first to evaluate delays related to DBT revealing the least delay occurring due to the late arrival of Interventional cardiologists. Our data emphasizes the importance of performing a detailed time analysis of the DBT.
Hegemonic femininity, femonationalism and the far-right
Authors: Montiel-McCann Camila 
Published: July 2024

Abstract
The burka has become a key symbol of the supposed ‘Islamification’ of Europe and has led to a series of ‘burka
bans’ (Bouattia 2019; Bracke 2012; Hancock 2015). In the debate surrounding these bans, a ‘femonationalist convergence’ has
been identified by Farris (2012, 2017) in
which the nationalist political right, neoliberal policy makers, and some feminist organisations converge in adopting the language
of gender equality to argue that the burka is a symbol of patriarchal oppression. In this paper, I relate this femonationalist
convergence to the maintenance of hegemonic femininity, which can be broadly defined as the privileging of femininity that is
complementary to white supremacist capitalist patriarchy (hooks 2000). Using feminist
critical discourse analysis (Lazar 2005), I analyse the representation of Muslim women
in an article on the burka written by former Prime Minister, Boris Johnson, for The Telegraph in 2018. I show how
Johnson instrumentalises femonationalist discourse to justify his Islamophobic marginalisation of Muslim women. I conclude that
Johnson used this article to lay the groundwork for his Conservative leadership bid the following year and to garner popular
support for a shift to the far-right in British politics.
Reservoir computing with a random memristor crossbar array
Authors: Wang Xinxin , Li Huanglong 
Published: July 2024

Abstract
Physical implementations of reservoir computing (RC) based on the emerging memristors have become promising candidates of unconventional computing paradigms. Traditionally, sequential approaches by time-multiplexing volatile memristors have been prevalent because of their low hardware overhead. However, they suffer from the problem of speed degradation and fall short of capturing the spatial relationship between the time-domain inputs. Here, we explore a new avenue for RC using memristor crossbar arrays with device-to-device variations, which serve as physical random weight matrices of the reservoir layers, enabling faster computation thanks to the parallelism of matrix-vector multiplication as an intensive operation in RC. To achieve this new RC architecture, ultralow-current, self-selective memristors are fabricated and integrated without the need of transistors, showing greater potential of high scalability and three-dimensional integrability compared to the previous realizations. The information processing ability of our RC system is demonstrated in asks of recognizing digit images and waveforms. This work indicates that the ‘nonidealities’ of the emerging memristor devices and circuits are a useful source of inspiration for new computing paradigms.
Shape memory polymer lattice structures with programmable thermal recovery time
Authors: Ji Jinyu , Zhang Kai , Guo Xiaogang 
Published: July 2024

Abstract
Shape memory polymer (SMP) lattice structures have garnered considerable attention due to their intrinsic capability for self-recovery and mechanical reconfiguration. The temporal path, encompassing aspects such as recovery time and deployment sequence, of the shape recovery process in SMP lattice structures holds paramount significance across various domains, including but not limited to medical devices and space deployable structures. Nonetheless, the programming of shape recovery time or deployment sequences in SMP lattice structures, particularly in scenarios devoid of external controllers, remains a challenge. In addressing these challenges, this study presents a novel class of SMP structures endowed with customizable thermal recovery times and programmable deployment sequences, leveraging the influence of structural geometry. Notably, the programmable recovery time and serialized deployment behavior of the proposed SMP lattice structure are achieved within a constant temperature environment, obviating the need for external time-varying stimuli. Finite element simulations and experimental validations corroborate that the proposed SMP structures can be programmed to exhibit recovery times spanning from mere seconds to several hundred seconds. Moreover, a three-stage sequential recovery behavior is attained without necessitating prior local configuration programming. Furthermore, exploiting the distinctive sequential reversibility inherent in a constant high-temperature environment, the designed lattice structure showcases the ability to transition to multiple distinct stable configurations by modulating the duration of high-temperature exposure. The proposed recovery time programmable SMP lattice structure thus presents a viable avenue for realizing intricate multistage controllable shape-shifting structures devoid of external control equipment.
Development of enhanced force models to analyze the nonlinear hysteresis response of miniaturized pneumatic artificial muscles
Authors: Zabihollah Shakila , Moezi Seyed Alireza , Sedaghati Ramin 
Published: July 2024

Abstract
Miniaturized pneumatic artificial muscles (MPAMs), designed to replicate natural muscle actuation, offer unique attributes such as a high power-to-weight ratio, flexibility, easy integration, and compactness, making them favourable for many applications. The present paper aims at the development of an accurate semi-analytical force model considering the effect of the bladder material and friction terms to predict the nonlinear force-deformation response of MPAMs during contraction and expansion cycles. Existing force models for MPAMs exhibit limitations to accurately capturing the force-deformation behaviours due to several simplification factors. This study enhances these models by integrating correction terms to accurately address the nonlinearity and frictional effects exhibited by MPAMs. An analysis of the hysteresis loops resulting from the cyclic loading and unloading of MPAMs under specific pressures is undertaken to compare different methodologies in order to determine the most accurate correction terms. To investigate the nonlinear behaviour of MPAMs, the stress-strain relationship of the bladder material and results from force-deformation experimental tests on the entire actuator are considered and for the effect of friction term, theoretical and empirical approaches are investigated. Results suggest that the theoretical force model based on analytical and empirical friction forces, respectively, slightly overestimates and underestimates the force experienced by MPAMs during contraction while slightly underestimate and overestimates during expansion, respectively. A comparative analysis between MPAMs featuring Ecoflex-50 silicone and Ecoflex30 + PDMS mixture as bladder materials has also been conducted to further investigate the effect of bladder materials on their force and contraction outputs under inlet pressures ranging from 0 kPa to 300 kPa. It is shown that the MPAM feauting Ecoflex-50 bladder, exhibits lower dead-band pressure and an overall reduced blocked force in comparison to MPAM with bladder made of Ecoflex30 + PDMS while exhibiting a substantially enhanced free contraction capacity.
Design and experimental study of a stepped magnetorheological damper with power generation
Authors: Chen Yingjie , Yang Xiaolong , Geng Xiumei , Deng Xiaoshu , Zhou Shiying 
Published: July 2024

Abstract
Traditional vehicle suspension magnetorheological dampers have problems with low output damping force and require additional energy input to operate, to improve the performance of the vehicle suspension magnetorheological damper, in this paper, we propose and investigate a stepped magnetorheological damper structure with power generation, and conducts structural design and magnetic circuit analysis. The effects of different currents, damping gaps, coil slot positions, and coil turns on the damping performance of the stepped magnetorheological damper with power generation are numerically studied. The magnetic circuit sensitivity analysis of the power generation structure and the magnetorheological damper structure is also performed. Experiments have verified the effects of different input excitations on damping and energy-feeding performance, and the results of numerical analysis have been verified. The results show that when the excitation coil is wound for 257 turns, the magnetic circuit requirements are met. And the influence of different amplitudes, frequencies, and currents on the output damping force was studied through experiments. The results showed that the damping force would increase with the increase of single parameter values. When the amplitude was 7 mm, the frequency was 1 Hz, and the current was 2 A, the output damping force could reach 4500 N, meeting the requirements for use.
Finite element analysis based verification of shape estimation performance according to displacement conditions and module types of FBG bending sensor
Authors: Kim Jiwon , Lee Hyun-Woo , Kim Dae-Hyun 
Published: July 2024

Abstract
This study proposes a novel, versatile sensor application solution suitable for various environments by verifying the shape estimation performance of three different module types of an FBG bending sensor based on finite element analysis. FBG bending sensors, including the individual attachment type, triangular stacking type, and band type, were attached to the structure. Subsequently, two simple plane displacement and one complex 3D displacement were applied to the structure to derive the strain for nine cases through finite element analysis. The shape estimation performance was then verified through a simulation based on the previously derived strain. As a result of verifying the shape estimation performance, it was confirmed that all three module types had high performance under simple plane displacement condition, whereas individual attachment types had better performance under complex 3D displacement condition. However, it’s important to note that the triangular stacking type and band type, with their small spacing between FBGs, have been developed to overcome the limited attachment conditions of the individual attachment type and to streamline the manufacturing process of the FBG bending sensors. Therefore, it is possible to select the FBG bending sensor according to the installation conditions of the structure to be applied and the required sensor performance by comprehensively considering the performance verification results of this study and the characteristics of the module types.
Ultrasound evaluation of polymathic methacrylate (PMMA) gel dosimeter doped with copper oxide (CuO) nanoparticles
Authors: Salman Mohammed Dawood , Radzi Yasmin Md , Rahman Azhar Abdul , Oglat Ammar A 
Published: July 2024

Abstract
A new gel dosimeter was synthesized using methyl methacrylate, gelatin, deionized water, N, N′-methylene bis(acrylamide), copper oxide nanoparticles (CuO NPs), and tetrakis (hydroxymethyl)phosphonium chloride (THPC). The PMMA polymer gel doped with CuO NPs was manufactured under normal atmospheric conditions. In detail, an enhanced dose response of the prepared PMMA was noticed as a function of the applied radiation exposure from 2 to 10 Gy with

R

2

=
0.974

and sensitivity of 0.025. In conjunction, further enhanced dose response was noticed upon the addition of CuO nanoparticles wherein dose response increments from 0.042 to 0.08 at 2 Gy and 0.25 to 0.325 at 10 Gy for PMMA samples doped with 0.5% and 1% of CuO nanoparticles, respectively. In meanwhile, the speed of sound and attenuation coefficient analysis demonstrated linear correlation (

R

2

≥
0.97

) between the applied radiation along with the attained dose response values. This linear relationship is attributed to the homogeneous distribution of CuO NPs and the consistent properties of the gel material, confirming the potential of CuO-doped PMMA gels for effective radiation dose measurement. These results underscore the adaptability of polymer gel dosimeters as a standard dosimetric material suitable for diverse applications.
Structural and optical characterizations of zircon and zirconia nanopowders derived from zircon sands
Authors: Pratama Detak Yan , Hariyanto Budi , Purwaningsih Sri Yani , Hatta Agus Muhamad , Pratapa Suminar 
Published: July 2024

Abstract
This study explores the structural and optical properties of zircon (ZrSiO4) and zirconia (ZrO2) nanopowders using two types of natural Indonesian zircon sands. The former powders were synthesized through dissolution and non-dissolution methods, while the latter powders were synthesized using alkali fusion and co-precipitation techniques. x-ray fluorescence (XRF) analysis revealed a reduction in impurities post-synthesis. X-ray diffraction (XRD) and Scanning Electron Microscopy (SEM) analyses indicated that the dissolution process yielded pure zircon, whereas the non-dissolution method resulted in the presence of minor additional phases. For zirconia, all samples exhibited a tetragonal phase, albeit with varying structures. Optical properties were investigated using UV–vis spectroscopy, which showed that both materials exhibit high absorption in the ultraviolet region, with slight differences in wavelengths peak. Consequently, zircon and zirconia demonstrated similar band gap energies ranging from 3.76 to 3.95 eV and 3.99 to 4.06 eV, respectively. Photoluminescence testing further revealed identical emission peaks 350 nm for both materials, highlighting their comparable optical characteristics. This study provides valuable understandings into the synthesis and optical properties of zircon and zirconia nanopowders derived from Indonesian zircon sands, emphasizing their potential applications in various optical and electronic fields.
Exploring the structural, electronic, and optical properties of novel two-dimensional ABX-type materials
Authors: Mir Showkat H , Yadav Vivek K 
Published: July 2024

Abstract
A first-principles study of the structural, electrical, and optical properties of graphene-like two-dimensional (2D) materials ABX (A=Na/K, B=C/Si/Ge, and X=N/P/As) such as NaCN, KCN, NaCP, KCP, etc was undertaken using state-of-the-art Density Functional Theory (DFT). The investigation encompasses essential parameters such as structural stability through ab initio molecular dynamics (AIMD), electronic structure, and dielectric constants. The AIMD measurements reveal that the structures stay stable for up to 10 picoseconds (ps). Band structure calculations at the PBE level of theory revealed that most materials are semi-conducting with a band gap of 1-3 eV, except NaCN and KCN, which exhibited insulating behaviour. Using hybrid functional (HSE), only eight materials were identified to have a band gap in the visible range. Optical properties have also been investigated to understand their interaction with light. Peaks in the imaginary component of the dielectric function were attributed to inter-band transitions. Several materials were discovered to be optimal for photo-catalysis, while six were found to exhibit conductivity of the order of ∼1012 (Ω−1cm−1s−1) at room temperature.
A novel comprehensive method for weak signal blind detection based on adaptive quasi-periodic potential stochastic resonance and its application in bearing fault detection
Authors: He Lifang , Jiang Zhiyuan , Gao Yanxin 
Published: July 2024

Abstract
In order to solve the common output saturation of stochastic resonance systems and the limitation of classical index SNR for blind detection, a novel adaptive quasi-periodic potential stochastic resonance blind detection method is proposed. First, a model of quasi-periodic potential stochastic resonance (QPPSR) possessing infinite steady state is constructed and analyzed for its structure change pattern. The superior performance of the model is verified by using the fourth-order Runge–Kutta algorithm. Secondly, the mechanism of QPPSR is analyzed using the probability flow method, which reveals the relationship between system parameters and performance. Again, a novel comprehensive blind detection index (CBDI) is exquisitely constructed to make up for the shortcomings of each indicator. Finally, CBDI and QPPSR are constructed into an adaptive blind detection system and applied to bearing fault detection. The results analyzed by experiments verify the good engineering application prospect of CBDI-QPPSR.
PPN meets EFT of dark energy: post-Newtonian approximation in higher-order scalar-tensor theories
Authors: Saito Jin , Yao Zhibang , Kobayashi Tsutomu 
Published: July 2024

AbstractWe study the post-Newtonian limit of higher-order scalar-tensor theories that are degenerate in the unitary gauge. They can be conveniently described by the effective field theory (EFT) of dark energy. We determine all the parametrized post-Newtonian (PPN) parameters in terms of the EFT of dark energy parameters. Experimental bounds on the PPN parameters are then translated to constraints on the EFT parameters. We present a Lagrangian of a unitary degenerate higher-order scalar-tensor theory characterized by a single function of the kinetic term of the scalar field whose PPN parameters have the same values as in general relativity.
Speed of sound measurements and derived third and fourth acoustic virial coefficients of supercritical neon
Authors: Dietl Tobias , El Hawary Ahmed , Gavioso Roberto M , Hellmann Robert , Meier Karsten 
Published: July 2024

Abstract
We report comprehensive and accurate measurements of the speed of sound in neon. These measurements were carried out by a double-path-length pulse-echo technique and cover the temperature range between 200 K and 420  K with pressures up to 100 MPa. The standard uncertainties are 1.9 mK in temperature, 22 parts in 106 in pressure and 35 parts in 106 in speed of sound. The third and fourth acoustic virial coefficients of neon were derived from the speed of sound data in the temperature range of the measurements by fitting a fourth-order acoustic virial expansion in pressure with the second acoustic virial coefficient constrained from first-principles calculations. To support our claimed uncertainty, we determined the ratio

M

/

γ

0

between the molar mass M and the ideal-gas heat capacity ratio

γ

0

of the neon sample with a relative standard uncertainty of 7.7 parts in 106 by additional speed of sound measurements using a spherical resonator at 273.16 K.