bluuebunny/crossref_metadata_2025_split huggingface dataset:
Associations between quality of relationships and life satisfaction of older mothers in Estonia, Germany, Russia and China
Authors: WU JING , KASEARU KAIRI , VÄRNIK AIRI , TOODING LIINA-MAI , TROMMSDORFF GISELA 
Published: May 2015

ABSTRACTThe aim of the current study is to examine the associations between the quality of relationships and life satisfaction of older mothers in Estonia, Germany, Russia and the People's Republic of China, based on the assumptions of the Family Change Theory. The role of satisfaction with family life as the probable mediating factor is considered. Estonian older mothers reported the least admiration and intimacy in their relationships with their adult daughters, and the least satisfaction with family life compared to German, Russian and Chinese mothers. German older mothers perceived the most admiration from their adult daughters and were the most satisfied with both their family and general life. Russian older mothers were the least satisfied with their general life compared to their counterparts in Estonia, Germany and China. The results from the Structural Equation Modelling showed that the relationship between satisfaction with family life and general life satisfaction was statistically significant in all countries except Russia. The satisfaction with family life as a mediating factor might strengthen the positive and negative aspects of intergenerational relationships on the life satisfaction of older mothers. The findings indicated that the emotional closeness and intergenerational relationships in families during the process of transition and globalisation play an important role in the life satisfaction of older mothers in these four countries.
Bill Dixon's Voice (Letter)
Authors: PORTER ERIC 
Published: May 2015

AbstractIn November 1966 composer and improviser Bill Dixon recorded a seventeen-minute-long “voice letter” to jazz writer Frank Kofsky. This letter may be analyzed as a critical intervention by Dixon, an attempt to change the context of interpretation around improvised music. But the voice letter may also be heard and analyzed as a kind of performance. As Dixon speaks, one can hear the rumbling and roar of the city as well as the staccato sounds of car and truck horns unfolding in dynamic counterpoint to his words. In this essay, I put the voice letter into dialogue with Dixon's personal history, his writings and interview statements, and some of his contemporaneous musical and multi-generic projects, especially his collaboration with dancer and choreographer Judith Dunn. I show how the letter maps Dixon's and Dunn's positions within a geography of intellectual circles, experimental artistic communities, and low-wage employment networks. By extension, I examine how the voice letter, as critical intervention and performance, points us to a nuanced understanding of black experimental music of the 1960s as a socially inflected, self-conscious and, ultimately, serious engagement with various modes of artistic production and thought, carried out under conditions of both precarity and inspiration.
First distributional record of Nitokra affinis Gurney, 1927 (Copepoda: Harpacticoida: Ameiridae) from Vellar estuary (south-east India): structural and molecular evidence
Authors: Rajthilak C. , Santhanam P. , Raja M. , Suman T.Y. , Rajasree S.R. Radhika , Ramkumar R. , Perumal P. 
Published: May 2015

The harpacticoid copepod,Nitokra affinisGurney, 1927 was recorded from Vellar estuary (south-east India) for the first time. This species was consistently found in plankton samples collected during June and July, 2010. The samples were collected by the horizontal towing of a plankton net for 20 min. In this paper, we provide drawings and descriptions ofNitokra affinisand discuss the possible mechanisms of its introduction. We also compare a 769 bp sequence of its 18S ribosomal (r) DNA with already publicly available sequences, which is characterized as a meaningful barcode for the subspecies identification ofNitokra affinisin the future.
Histological variant as the significant predictor of survival in patients with lymph node positive urothelial carcinoma of the bladder
Authors: Kim Hyung Suk , Moon Kyung Chul , Jeong Chang Wook , Kwak Cheol , Kim Hyeon Hoe , Ku Ja Hyeon 
Published: May 2015

AbstractThe aim of this study was to evaluate the impact of histological variants of urothelial carcinoma (UC) on survival outcomes in patients with lymph node (LN) positive UC of the bladder. We reviewed and analyzed the clinical data from 424 patients who underwent radical cystectomy (RC) with pelvic lymph node dissection (PLND) for UC of the bladder and who did not receive neoadjuvant chemotherapy in our institution between 1991 and 2012. In total, 92 patients (21.7%) had histologically confirmed LN positive disease. In the LN negative group (332 patients), histological variants of UC were not a significant predictor in univariate analysis. However, in the LN positive group, histological variants of UC were a significant independent prognostic factor of overall survival (hazard ratio (HR) 3.54; 95% confidence interval (CI) 1.77–7.08, p < 0.001) and cancer specific survival (HR 3.66; 95% CI 1.69–7.90, p = 0.001) in both uni-variate and multivariate Cox regression analyses. The presence of histological variants of UC may indicate a worse prognosis in LN positive patients after RC with PLND for UC of the bladder and more aggressive adjuvant therapy may be required for the improvement of postoperative survival.
Odd-parity magnetoresistance in pyrochlore iridate thin films with broken time-reversal symmetry
Authors: Fujita T. C. , Kozuka Y. , Uchida M. , Tsukazaki A. , Arima T. , Kawasaki M. 
Published: May 2015

AbstractA new class of materials termed topological insulators have been intensively investigated due to their unique Dirac surface state carrying dissipationless edge spin currents. Recently, it has been theoretically proposed that the three dimensional analogue of this type of band structure, the Weyl Semimetal phase, is materialized in pyrochlore oxides with strong spin-orbit coupling, accompanied by all-in-all-out spin ordering. Here, we report on the fabrication and magnetotransport of Eu2Ir2O7 single crystalline thin films. We reveal that one of the two degenerate all-in-all-out domain structures, which are connected by time-reversal operation, can be selectively formed by the polarity of the cooling magnetic field. Once formed, the domain is robust against an oppositely polarised magnetic field, as evidenced by an unusual odd field dependent term in the magnetoresistance and an anomalous term in the Hall resistance. Our findings pave the way for exploring the predicted novel quantum transport phenomenon at the surfaces/interfaces or magnetic domain walls of pyrochlore iridates.
Tail-scope: Using friends to estimate heavy tails of degree distributions in large-scale complex networks
Authors: Eom Young-Ho , Jo Hang-Hyun 
Published: May 2015

AbstractMany complex networks in natural and social phenomena have often been characterized by heavy-tailed degree distributions. However, due to rapidly growing size of network data and concerns on privacy issues about using these data, it becomes more difficult to analyze complete data sets. Thus, it is crucial to devise effective and efficient estimation methods for heavy tails of degree distributions in large-scale networks only using local information of a small fraction of sampled nodes. Here we propose a tail-scope method based on local observational bias of the friendship paradox. We show that the tail-scope method outperforms the uniform node sampling for estimating heavy tails of degree distributions, while the opposite tendency is observed in the range of small degrees. In order to take advantages of both sampling methods, we devise the hybrid method that successfully recovers the whole range of degree distributions. Our tail-scope method shows how structural heterogeneities of large-scale complex networks can be used to effectively reveal the network structure only with limited local information.
Three-Dimensional Image of Cleavage Bodies in Nuclei Is Configured Using Gas Cluster Ion Beam with Time-of-Flight Secondary Ion Mass Spectrometry
Authors: Masaki Noritaka , Ishizaki Itsuko , Hayasaka Takahiro , Fisher Gregory L. , Sanada Noriaki , Yokota Hideo , Setou Mitsutoshi 
Published: May 2015

AbstractStructural variations of DNA in nuclei are deeply related with development, aging and diseases through transcriptional regulation. In order to bare cross sections of samples maintaining sub-micron structures, an Ar2500+-gas cluster ion beam (GCIB) sputter was recently engineered. By introducing GCIB sputter to time-of-flight secondary ion mass spectrometry (TOF-SIMS), we analyzed the 3D configuration and chemical composition of subnuclear structures of pyramidal cells in the CA2 region in mouse brain hippocampus. Depth profiles of chemicals were analyzed as 3D distributions by combining topographic analyses. Signals corresponding to anions such as CN− and PO3− were distributed characteristically in the shape of cell organelles. CN− signals overlapped DAPI fluorescence signals corresponding to nuclei. The clusters shown by PO3− and those of adenine ions were colocalized inside nuclei revealed by the 3D reconstruction. Taking into account their size and their number in each nucleus, those clusters could be in the cleavage bodies, which are a kind of intranuclear structure.
Hypermethylated Epidermal growth factor receptor (EGFR) promoter is associated with gastric cancer
Authors: Weng Xiaoling , Zhang Hong , Ye Junyi , Kan Mengyuan , Liu Fatao , Wang Ting , Deng Jiaying , Tan Yanfang , He Lin , Liu Yun 
Published: May 2015

AbstractEpidermal growth factor receptor (EGFR) is a member of the receptor tyrosine kinases ErbB family and it is found to be overexpressed in gastric cancer. However, the mechanism of the regulation of the EGFR expression is still unknown. We used the Sequenom EpiTYPER assay to detect the methylation status of the EGFR promoter in normal and tumour tissues of 30 patients with gastric cancer. We also carried out quantitative real time PCR (qPCR) to detect the expression level of EGFR in our 30 patients. Notably, increased methylation level at EGFR promoter was found in tumour tissues than the corresponding adjacent noncancerous. In both Region I DMR and Region II DMR detected in our study, tumor tissues were significantly hypermethylated (P = 2.7743E−10 and 2.1703E−05, respectively). Region I_⊿CpG_2 was also found to be associated with the presence of distant metastasis (P = 0.0323). Furthermore, the results showed a strongly significant association between the relative EGFR expression and the EGFR methylation changes in both Region I and Region II (P = 0.0004 and 0.0001, respectively). Our findings help to indicate the hypermethylation at EGFR promoter in gastric cancer and it could be a potential epigenetic biomarker for gastric cancer status and progression.
Simple metal under tensile stress: layer-dependent herringbone reconstruction of thin potassium films on graphite
Authors: Yin Feng , Kulju Sampo , Koskinen Pekka , Akola Jaakko , Palmer Richard E. 
Published: May 2015

AbstractWhile understanding the properties of materials under stress is fundamentally important, designing experiments to probe the effects of large tensile stress is difficult. Here tensile stress is created in thin films of potassium (up to 4 atomic layers) by epitaxial growth on a rigid support, graphite. We find that this “simple” metal shows a long-range, periodic “herringbone” reconstruction, observed in 2- and 3- (but not 1- and 4-) layer films by low-temperature scanning tunneling microscopy (STM). Such a pattern has never been observed in a simple metal. Density functional theory (DFT)simulations indicate that the reconstruction consists of self-aligned stripes of enhanced atom density formed to relieve the tensile strain. At the same time marked layer-dependent charging effects lead to substantial variation in the apparent STM layer heights.
Four-pole galvanic vestibular stimulation causes body sway about three axes
Authors: Aoyama Kazuma , Iizuka Hiroyuki , Ando Hideyuki , Maeda Taro 
Published: May 2015

AbstractGalvanic vestibular stimulation (GVS) can be applied to induce the feeling of directional virtual head motion by stimulating the vestibular organs electrically. Conventional studies used a two-pole GVS, in which electrodes are placed behind each ear, or a three-pole GVS, in which an additional electrode is placed on the forehead. These stimulation methods can be used to induce virtual head roll and pitch motions when a subject is looking upright. Here, we proved our hypothesis that there are current paths between the forehead and mastoids in the head and show that our invented GVS system using four electrodes succeeded in inducing directional virtual head motion around three perpendicular axes containing yaw rotation by applying different current patterns. Our novel method produced subjective virtual head yaw motions and evoked yaw rotational body sway in participants. These results support the existence of three isolated current paths located between the mastoids and between the left and right mastoids and the forehead. Our findings show that by using these current paths, the generation of an additional virtual head yaw motion is possible.
Targets of drugs are generally and targets of drugs having side effects are specifically good spreaders of human interactome perturbations
Authors: Perez-Lopez Áron R. , Szalay Kristóf Z. , Türei Dénes , Módos Dezső , Lenti Katalin , Korcsmáros Tamás , Csermely Peter 
Published: May 2015

AbstractNetwork-based methods are playing an increasingly important role in drug design. Our main question in this paper was whether the efficiency of drug target proteins to spread perturbations in the human interactome is larger if the binding drugs have side effects, as compared to those which have no reported side effects. Our results showed that in general, drug targets were better spreaders of perturbations than non-target proteins and in particular, targets of drugs with side effects were also better spreaders of perturbations than targets of drugs having no reported side effects in human protein-protein interaction networks. Colorectal cancer-related proteins were good spreaders and had a high centrality, while type 2 diabetes-related proteins showed an average spreading efficiency and had an average centrality in the human interactome. Moreover, the interactome-distance between drug targets and disease-related proteins was higher in diabetes than in colorectal cancer. Our results may help a better understanding of the network position and dynamics of drug targets and disease-related proteins and may contribute to develop additional, network-based tests to increase the potential safety of drug candidates.
Evaluation and integration of cancer gene classifiers: identification and ranking of plausible drivers
Authors: Liu Yang , Tian Feng , Hu Zhenjun , DeLisi Charles 
Published: May 2015

AbstractThe number of mutated genes in cancer cells is far larger than the number of mutations that drive cancer. The difficulty this creates for identifying relevant alterations has stimulated the development of various computational approaches to distinguishing drivers from bystanders. We develop and apply an ensemble classifier (EC) machine learning method, which integrates 10 classifiers that are publically available and apply it to breast and ovarian cancer. In particular we find the following: (1) Using both standard and non-standard metrics, EC almost always outperforms single method classifiers, often by wide margins. (2) Of the 50 highest ranked genes for breast (ovarian) cancer, 34 (30) are associated with other cancers in either the OMIM, CGC or NCG database (P < 10−22). (3) Another 10, for both breast and ovarian cancer, have been identified by GWAS studies. (4) Several of the remaining genes--including a protein kinase that regulates the Fra-1 transcription factor which is overexpressed in ER negative breast cancer cells; and Fyn, which is overexpressed in pancreatic and prostate cancer, among others--are biologically plausible. Biological implications are briefly discussed. Source codes and detailed results are available at http://www.visantnet.org/misi/driver_integration.zip.
Interactional synchrony in chimpanzees: Examination through a finger-tapping experiment
Authors: Yu Lira , Tomonaga Masaki 
Published: May 2015

AbstractHumans often unconsciously coordinate behaviour with that of others in daily life. This interpersonal coordination, including mimicry and interactional synchrony, has been suggested to play a fundamental role in social interaction. If this coordinative behavior is socially adaptive, it may be shared with other highly social animal species. The current study targeted chimpanzees, which phylogenetically are the closest living relatives of humans and live in complex social groups and examined whether interactional synchrony would emerge in pairs of chimpanzees when auditory information about a partner’s movement was provided. A finger-tapping task was introduced via touch panels to elicit repetitive and rhythmic movement from each chimpanzee. We found that one of four chimpanzees produced significant changes in both tapping tempo and timing of the tapping relative to its partner’s tap when auditory sounds were provided. Although the current results may have limitations in generalizing to chimpanzees as a species, we suggest that a finger-tapping task is one potential method to investigate interactional synchrony in chimpanzees under a laboratory setup.
Refractory Thoracolumbar Cerebrospinal Fluid Leak after Multiple Spinal Ependymoma Resections Treated with External Ventricular Drainage
Authors: Galgano Michael A. , Hazama Ali , Deshaies Eric M. 
Published: May 2015

Study Design Case report. Objective Temporary external ventricular drainage for refractory thoracolumbar cerebrospinal fluid (CSF) leak is not reported in the literature. We describe a recent case that utilized this technique. Methods Retrospective review of the patient's case notes was performed and the literature on this subject reviewed. Results The patient underwent multiple complex spinal surgeries for resection of innumerable metastatic ependymoma lesions. A case of significant refractory CSF leak developed and as a last resort a right frontal external ventricular drain was placed. The CSF leak ceased, and the patient was eventually discharged home without further complication. Conclusion External ventricular drainage can be a viable option for temporary proximal CSF diversion to treat refractory thoracolumbar CSF leaks.
Oxford Recovery Housing: Length of Stay Correlated with Improved Outcomes for Women Previously Involved with the Criminal Justice System
Authors: Jason Leonard A. , Salina Doreen , Ram Daphna 
Published: May 2015

Background Housing plays a crucial role in providing resources for and aiding an individual's reentry into the community following incarceration and substance use treatment. As such, this study examined the influence of recovery homes on a sample of former female substance-using women with criminal justice involvement. Methods Two hundred women who had been involved with the criminal justice system within the preceding 2 years were recruited from multiple sites in metropolitan Chicago. These women were assigned to either 1 of 2 conditions: Oxford House (OH) recovery homes or usual aftercare (UA). Results Those with longer stays in OH (6 months or more) had better outcomes in terms of alcohol and drug use, employment, and self-efficacy than those with shorter stays. Outcomes for those who stayed in OH were not appreciably different than the UA condition on substance use and employment, but fewer deaths occurred for those in the OH condition. Conclusions Findings suggest that length of stay of 6 or more months is critical for those in recovery homes, but it is important for us to better understand the processes through which longer stays influence better outcomes.
Building the research culture in an African business school
Authors: Puplampu Bill Buenar 
Published: May 2015

Purpose– This paper aims to report the efforts to reverse a dire research output trend at a Ghanaian Business School, following a similar effort at a business school in New Zealand in the 1990s. African universities are often challenged by resource constraints, ageing faculty and low compensation regimes. The consequences of these challenges are particularly felt in the area of the research output of faculty members in the business and management area. The problem of low research output has been written about by management scholars who lament the weak showing of African management faculty in reputable journals and top-notch conference presentations.Design/methodology/approach– This is a qualitative and phenomenological study of an applied intervention. Using a combination of open-ended questionnaires as well as open forums attended by faculty members of the business school, views, perceptions and opinions on factors mitigating research and issues on research culture were collected and analysed. Descriptive analyses were used to collate the dominant views and frequency of mention of such views.Findings– Using the descriptive accounts of faculty of the Business School, the research finds that a research-oriented culture expressed through factors such as leadership, institutional support, articulation or otherwise of relevant values have significant impacts on research output.Research limitations/implications– Based on the impacts reported here, this paper advances an intervention model to assist efforts towards improving the research culture and scholarly outputs in business schools in Africa. The paper also proposes a conceptual and research framework for examining and influencing the organisational and research culture of universities in Africa.Originality/value– This paper is perhaps the only attempt to examine research culture in an African business school. It suggests that the research culture in a business school or faculty can be developed, reinvented or influenced and that research in African universities will not “just happen”, it has to be carefully planned for, nurtured and built into the fabric of university culture. This has significant implications for the growing effort to bring African scholarship in the management areas up to the point where it can more directly impact management thinking.