bluuebunny/crossref_metadata_2025_split huggingface dataset:
2013 – Randomized Controlled Trial Comparing Individually-based And Family-based Treatments For Internalizing, Externalizing, And Family Symptoms In Hispanic Youth
Authors: Santisteban D. , Mena M. , McCabe B. 
Published: July 2013

An RCT was conducted to test Culturally Informed and Flexible Family Treatment for Adolescents (CIFFTA) to an individuallyoriented treatment (TAU) in modifying Internalizing and Externalizing symptoms, and family conflict. CIFFTA integrates individual, family, and psycho-educational interventions using an adaptive approach to tailor the treatment to unique client characteristics. One hundred-thirty Hispanic adolescents 11–14 years of age were randomly assigned to 16 weeks of treatment. A pre-post design (4 month post baseline) was used. Parent reports are highlighted here. Adolescents showed similar change.Retention in Treatment: Participants in CIFFTA had about twice the odds of being retained as those in TAU, χ2 (1, N = 169) = 4.02, p = .045, OR = 2.15.Change in Family Conflict: There were significant Time, F(1, 131) = 140.43, p < .001, and Time × Condition, F(1, 131) = 4.12, p = .042, effects. Parents reported reductions in both conditions but effects were greater in CIFFTA.Change in Externalizing Symptoms: There was a significant Time effect, F(1, 135) = 109.83, p < .001, but no Time × Condition effect, F(1, 135) = 0.42, p = .518. Parents reported moderate-to-large decreases in externalizing problems in both conditions. Change in Internalizing Symptoms: There were significant Time, F(1, 135) = 110.08, p < .001, and Time × Condition effects, F(1, 135) = 5.12, p = .025. Parents reported moderate-to-large decreases in depression in both conditions but were larger for TAU.The clinical and research implications of this research will be presented along with some preliminary results of tests of mediation.
2015 – Impulsivity And Stress As Risk Factors For The Development Of Alcohol Dependence
Authors: Marin Mayor M. , Verdura Vizcaino E. , Codesal Julian R.A. , Lopez Alvarez J. , Rubio Valladolid G. 
Published: July 2013

IntroductionIt is well known that impulsivity and stress are risk factors for the development of addictive disorders, and more specifically alcohol dependence. Impulsivity has two dimensions: behavioural inhibition and delay of reward. The Fear- Conditioning paradigm of the Startle response (SR), which refers to the potentiation of the startle amplitude after the exposure to aversive stimulus, can be used as a stress test. The aim of this study was to explore the correlation between impulsivity laboratory tasks and the Fear-Conditioning (FC) paradigm of the SR as risk factors for the development of alcohol dependence.MethodsThe sample included 40 abstinent alcoholic men, who met DSM-IV criteria for Alcohol Dependence and had been abstinent for at least one month. Impulsivity was assessed using two laboratory tests: Stop-Signal Task (SST) and Differential Reinforcement for Low-Rate Responding (DRL6). The FC paradigm of the SR was used as a stress test. Patients were compared to 40 matched controls.ResultsWe found a positive correlation between SST tasks and the FC paradigm of the SR (p < 0,05) and a negative correlation between the DRL6 tasks and the FC paradigm of the SR (p < 0,05) in the patient's group. This significant correlation was not found in controls.ConclusionsImpulsivity and stress are significantly correlated in alcohol dependent patients. This means that while healthy subjects cope with stress, alcohol dependent patients react with higher impulsivity when they are exposed to stress situations and this could lead them to drink alcohol to relieve anxiety and depressive symptoms.
2017 – Clinical And Socio-demographic Characteristics Of College Students In The Northeast Of Brazil Exposed To Traumatic Experiences: a Prevalence Census Study Protocol
Authors: Netto L.R. , Quarantini L.D.C. , Pereira J.L. , Feitosa J.R. , Pettersen K.M. , Duarte A. , Loureiro A. , Mundim D. , Santana R. , Albuquerque I. , Barbosa R. 
Published: July 2013

BackgroundAdolescence and early adulthood are the most vulnerable period of life for exposure to traumatic experiences (70% of their deaths are due to external causes). The Post Traumatic Stress Disorder (PTSD) is characterized by dysfunctional symptoms that cause distress or social, academic and occupational impairment, and results from exposure to a traumatic stressor. There is no consensus in the literature about why some individuals experience PTSD after traumatic events and not others. The aim of this multicentre study is to describe clinical and socio-demographic characteristics and academic performance in college student's population in the Northeast of Brazil, identifying traumatic experiences exposure patterns, and investigating the impulsivity's influence in the development of PTSD, as well as the impact of early traumatic experiences in vulnerability or resilience in this population.Methods/design2282 subjects completed the protocol between April and July 2011 in a sample census of seven (public and private) college institutions in three metropolitan regions of the Brazilian Northeast, aiming to cover different academic areas (exact, biological, humanities /arts). All students aged 18 or older, enrolled and attending to the first and last theoretical period were eligible, and accessed by previously trained researchers. The self applied protocol consisted of socio-demographic questionnaire and validated scales of: Impulsivity (BIS-11), PTSD (PCL-C) and Trauma History Questionnaire (THQ). Data were entered into SPSS 15.0. Prevalence Ratio and Logistic Regression technique will be used to analyze the association between dependent and independent variables of the study, that was approved by Bahia and Paraiba's ethics committees.
2019 – Case Report: Comorbidity Of Malignant Forms Of Anorexia Nervosa And Narcissistic Personality Disorder
Authors: Stipčević M. , Godan B.J. , Marčinko D. 
Published: July 2013

Anorexia nervosa is a psychiatric disorder with a prevalence of circa five percent in young women population, with an increased tendency of frequent occurrence over the past twenty years. Although the diagnosis is relatively simple and straightforward, the treatment of these patients is often time-consuming and challenging for clinicians, as the occurrence of malignant and persistent forms of the condition is becoming ever more common. Resistant clinical diagnoses usually arise through comorbidity with other psychiatric disorders. Counted among them, first of all, are personality disorders.A.N. is treated by means of using various groups of psychopharmacological drugs in combination with psychotherapeutic treatment, with intention to establish a favorable therapeutic relationship and stability of the patient. Psychotherapeutic part of the treatment gains in importance when the condition occurs in comorbidity with personality disorders. Supportive treatment measures, namely aggressive rehydration, caloric values compensation via probes and and catheters are often an integral part of the treatment, and become particularly important when faced with treating malignant forms of the condition.Presented case will show that the malignant forms of Anorexia Nervosa can only be understood through insight into the psychological foundations of personality and frequently accompanying disorders on Axis II (DSM-IV). The female patient in question displays a base borderline personality structure with dominant narcissistic tendencies which prompted the development of a malignant form of the condition and thus made the treatment significantly more difficult. Only early intervention with emphasis on the psychotherapy treatment can ensure a better long-term prognosis in such cases.
2025 – Audit Of Monitoring For Metabolic Syndrome In Medium Secure Forensic Wards In Roseberry Park Hospital, Middlesbrough, Uk
Authors: Nzekwe A. , Nzekwe V. , Udo I. 
Published: July 2013

IntroductionPersons receiving care in forensic settings face unique challenges. Long hospital stay combined with other factors such as reduced physical activity, unhealthy diets, smoking, serious mental illness, antipsychotic medications, all add up to increase their risk of acquiring metabolic syndrome, thereby increasing morbidity and mortality.AimPractice of monitoring for metabolic effects of an atypical antipsychotic- Clozapine was audited with the Maudsley Guideline as standard in 2 medium secure wards with 25 patients. It was conducted in 2011.ObjectivesWe checked whether blood lipids and body weight were monitored at baseline, at 3 months and then yearly; whether blood glucose and blood pressure were checked at baseline, at 4–6 months and then yearly.MethodsVarious sources of information were used including: paper medical records, electronic clinical entries, physical observation charts, medication prescription charts, Clozapine charts and acute hospital laboratory resultsResults24 patients (96%) were on antipsychotic medication. Of these, 23 patients were on atypicals. Of the latter, 8 persons were on Clozapine. No patient on Clozapine achieved a 100% monitoring on indices. Baseline monitoring for cholesterol, weight, blood glucose and blood pressure were 88%, 50%, 75% and 88% respectively. At midterm they were 50%, 100%, 38%, and 25% respectively. There were variable compliance with other indices at stipulated times. Lack of supporting infrastructure to facilitate compliance was identified.ConclusionThere was a need to adhere to existing guidelines which were also embodied in Trust policy to help manage metabolic syndrome.
2029 – Aripiprazole Withdrawal And Supersensitivity Psychosis: a Case Report
Authors: Lakhal M.H. , Rafrafi R. , Jomli R. , Ouanes S. , El Hechmi S. , Melki W. , El Hechmi Z. , Nacef F. 
Published: July 2013

IntroductionSupersensitivity psychosis is a drug-induced phenomenon which consists of psychotic relapse occurring upon decrease or withdrawal of antipsychotics. This phenomenon has been described with many antipsychotics. We report the case of supersensitivity psychosis associated with decreasing doses of aripiprazole in a Tunisian patient.Case descriptionMr. M. is a 26-year old Tunisian male with a diagnosis of bipolar disorder (DSM IV). He was diagnosed at the age of 17. For the last 2 years, his condition was stable with lithium 250 mg/day, valproic acid 500 mg/day and aripiprazole 15 mg/day. The patient had a good adherence to this regimen and could go to work and study. During that period he only had some depressive relapses. He never had psychotic symptoms. He decided himself to stop taking aripiprazole. The withdrawal was abrupt. Two days later, he began to experience auditory and visual hallucinations and persecutory delusion he never experienced before. He was hospitalized and he was put again on aripiprazole with increased doses to 20 mg/day. One week later his symptoms had improved significantly, he was experiencing less hallucinations. Two weeks later all the psychotic symptoms disappeared.DiscussionThis case illustrates the concept of supersensitivity psychosis. This concept refers to the proposal that chronic administration of dopamine-blocking agents increases sensitivity of dopamine receptors in the mesolimbic or mesocortical system. These dopamine-blocking agents over-react to normal levels of dopamine after drug discontinuation or reduction, thus producing psychotic symptoms, analogous to the proposed mechanism of tardive dyskinesia.
2035 – Depressive Disorders In Patients With Ischemic Heart Disease And Various Manifestations Of Metabolic Syndrome
Authors: Garganeeva N. , Rozin A. , Schastnyy E. , Belokrylova M. , Donov A. 
Published: July 2013

ObjectiveStudy of influence of depression on assessment of cardiovascular risk in IHD patients with components of metabolic syndrome (MS).Material and methodsAmong 376 IHD patients (59,1±10,3 years) 72,9% had AH, 40,2% DM of type 2 or disturbance of tolerance to glucose (DTG), 45,9% obesity, 42,2% dyslipidemia (DLP). Methods of investigation were as follows: clinicalpsychopathological, experimental-psychological, HADS, MADRS.ResultsDepressive disorders have been diagnosed in 109 IHD patients (29%) of cardiologic institution. 79,8% had affective disorders, 20,2% mixed anxiety-depressive reaction, organic depressive disorder. There were more often factors of cardiovascular risk and components of MS: frequency of AH (83,2% vs. 66,3%; p = 0,016), DM of type 2 and DTG (46,8% vs. 37,5%; p = 0,048), obesity (30,7 ± 3,9 vs. 29,5 ± 4,5; p = 0,015), abdominal obesity (100,0 ± 10,7 vs. 92,0 ± 9,6 cm; p = 0,02), DLP (42,2% vs. 31,1%; p = 0,04); TCh (6,03 ± 1,19 vs. 5,72 ± 1,31 mmol/l; p = 0,033); Ch-LPHD (0,83 ± 0,18 vs. 0,94 ± 0,29 mmol/l; p = 0,0015). We have noticed increase of cases of instable angina (16,5% vs. 8,2%; p = 0,02), post-infarction cardiosclerosis (41,3% vs. 39,3%; p = 0,043), surgical revascularization of myocardium (22,9% vs. 15,4%; p = 0,041), need for nitrates (23,4 ± 2,8 vs. 17,6 ± 2,9 tablets/week; p = 0,00001), invalidization (44% vs. 23,2%; p = 0,00001). During intake of antidepressants (SSRIs) higher scores according to depression rating scales remained by month 6 of psychotropic therapy.ConclusionsHigh frequency of association of factors of cardiovascular risk and components of MS in IHD patients with depressive disorders significantly exceeds indices in group without depression. Metabolic disturbances (DM of type 2, DTG, DLP), revealed in 65,1% of IHD patients with depression, decrease efficacy of antidepressant therapy.
2036 – Anesthesia In Pediatric Oncologic Patients Undergoing Radiotherapy
Authors: Taniguchi S. , Feltrin M. , Centroni Yamazaki A.F. , Negrão A.J. , Ropero J. 
Published: July 2013

IntroductionPediatric oncological patients undergoing radiotherapy require immobilization.ObjectivesThis study investigated the drugs administered and vital signs of these patients.MethodsOur study included 38 patients with mean age 29.40 ± 3.94 months, weight mean 14.64 ± 0.55 kg, height 90.47 ± 14.71 cm undergoing anesthesia for radiotherapy immobilization purpose.ResultsAll patients received sevoflurane 8% for induction and anesthesia maintenance and procedure period was 32.62 ± 2.41 minutes.Measured vital signs before anesthesia were: systolic arterial pressure 101.38 ± 2.05, diastolic arterial pressure 53.28 ± 1.80, heart rate 116.14 ± 1.80, respiratory rate 23.12 ± 0.93 and body temperature 36.01 ± 0.19.Vital signs after anesthesia were: systolic arterial pressure 96.00 ± 2.02, diastolic arterial pressure 49.20 ± 2.88, heart rate 111.63 ± 2.80, respiratory rate 23.51 ± 1.10, body temperature 36.43 ± 0.82 and oxygen saturation 97.74% ± 1.00.Emergence agitation related to the use of sevoflurane was observed in 84.21% (32) patients.Either propofol 0.5 - 4.4 mg/kg or nalbuphine 0.1-0.15 mg/kg or fentanyl 2-3.6 mg/kg controlled agitation after sevoflurane in 43.75% (14) patients.Flumazenil 0.02 mg/kg given to 5.26% (2) patients and haloperidol 1.44 mg/kg administered to 10.53% (4) and enhanced the agitation after sevoflurane.ConclusionThere were no significant difference between vital signs measured before and after anesthesia with sevoflurane. Emergence agitation due to the use of sevoflurane was observed.The use of benzodiazepines antagonist and neuroleptics should be evaluated in emergence agitation due to sevoflurane.
2038 – Help For The Individual In The End Of Life
Authors: Semke V. 
Published: July 2013

Way to conceptualization of process of rendering of assistance for aging patients allows broadening of front of joint action of psychotherapists, psychologists, sociologists, clinical geriatricians, creating valid perspectives of Russian nation. Such help is considered within the entire humankind, acute problem of mental health in contemporary world we may regard perspective of formation of successful scientific developments in the domain of geriatric help, as well as perspective of new branches of knowledge of “Homo noetic” in the new third millennium. We need breakage in psychology of workers of healthcare, researchers and patients. We need another graduate and postgraduate education, another upbringing at home and in the society. These positive shifts occur currently, giving the hope for huge success in the XXIst century.Namely on border of centuries (largely millenniums) we witness scaled rethinking of system of scientific paradigms, attitudes, priorities and values in the field of human mental health, passing various phases of his/her existence. Conditions of interaction in system “doctor-patient” change, people want to take part in their own fate, in assessment of level of their health, illness and even coming death, having possibility to choose informed partner collaboration. Largely, this is associated with change of essence and content of the entire psychiatric science, including gerontopsychiatry.
2040 – Clinical Characteristics Of Patients With Schizophrenia Associated With Drug And Alcohol Dependence
Authors: Dobrovolskaya A. , Sofronov A. , Savelyev A. , Zinovyev S. , Pashkovskiy V. 
Published: July 2013

ObjectiveTo analyze social, demographic and clinical characteristics of patients with schizophrenia and comorbidity drug dependence.MethodsClinical interview with specially elaborated formalized card. Patients were diagnosed according to ICD-10 criteria. 182 patients were treated in St Petersburg state mental hospital № 3 in 2005-2010.ResultsAlcohol, cannabis, and heroin tend to be the primary substances of abuse. According to the drug usage we form two groups. The first group (n = 105, 57,7%) consisted of patients who abuse alcohol only. The second group consisted of patients who use different types of drugs (n = 77, 42,3%). Both groups had high rates of unemployment, disability, length of stay in a psychiatric hospital.Schizophrenia patients with multidrug dependence (2nd group) were younger than patients with alcohol dependence only (1st group). Middle age of patients of 2nd group was 31, 38 ± 0, 94 and middle age of patients of 1st group was 42, 45 ± 1,14. Patients of both group were unemployed 92 (87, 61%) and 62 (80,52%) respectively.We identified statistically significant between-group differences in patients with paranoid schizophrenia. Patients of 1st group had paranoid schizophrenia higher 76 (72, 38%) than patients of 2nd group 39 (50, 65%). On the contrary, simple schizophrenia was diagnosed more often in patients of 2nd group 29, 87% and 14, 28% respectively.Drug dependence disorders come before schizophrenia manifestation significantly more often (51,95%) than alcohol use disorders (AUD) (31,43%).AUD occurred after schizophrenia manifestation (33, 33%) significantly more often than drug dependence disorders (12,9%).
2049 – Are Personality Traits Predictive Of Diagnosis In Adjustment Disorder And Depressive Episode
Authors: Doherty A. , Jabbar F. , Casey P.R. 
Published: July 2013

AimsIn this study we aimed to examine the characteristics of patients diagnosed with depressive episode or adjustment disorder, and to explore the interplay between these diagnoses and personality disorder/traits.MethodsPatients referred to the liaison psychiatry services at three Dublin hospitals and diagnosed with either a depressive episode or an adjustment disorder were recruited to this study. They were interviewed at time of diagnosis and again after six months using validated instruments, including SCAN (Schedule for Clinical Diagnosis in Neuropsychiatry - a semi-structured diagnostic interview schedule) and possible personality disorder as measured by SAPAS (Standardised Assessment of Personality - Abbreviated Scale).Results370 patients were recruited to the study, 185 of whom had a diagnosis of an adjustment disorder; the remainder were diagnosed with a depressive episode according to ICD-10 criteria. SCAN (Schedule for Clinical Diagnosis in Neuropsychiatry - a semi-structured diagnostic interview schedule) was not useful in distinguishing between these two diagnoses. Patients with a SAPAS score above 3 (cut-off for likely personality disorder) and a diagnosis of adjustment disorder had an increased risk of suicidal behaviour (p = 0.001). When both diagnostic groups were analysed together, patients with a SAPAS score above 3 had an increased risk of suicidal behaviour (p = 0.007).ConclusionsThere has been little prior research into personality disorder and its association with adjustment disorder. Personality traits are associated with a diagnosis of depression rather than adjustment disorder, but have a stronger association with suicidal behaviour in patients with a diagnosis of adjustment disorder.
2058 – Réhabilitation Psychiatrique Chez Des Patients Sous Mesures Judiciaires
Authors: Bougherab A. 
Published: July 2013

La psychiatrie pénitentiaire accueille des patients qui souffrent de troubles psychiatriques, qui ont commis des délits en lien avec leurs pathologies.Quelle approche thérapeutique à suivre pour ce type de patients lorsqu’on sait que qu’il y a deux grandes catégories de Troubles les patients qui souffrent de troubles psychotiques et les patients qui ont un probleme de trouble de personnalité notamment personnalité dyssociale.
2061 – Level Of Functioning In Early Onset Psychoses: Seven Years Follow-up Study
Authors: Remberk B. , Bażyńska A.K. , Bronowska Z. , Potocki P. 
Published: July 2013

IntroductionThere is a relative dearth of studies assessing the course of early onset psychoses especially other than schizophrenia.ObjectivesFollow-up assessment of level of functioning in early onset psychosis.AimsAnalysis of the course and outcome in early onset psychoses. Assessment of prognostic significance of psychopathological symptoms profile in the early course of illness.Methods144 patients with schizophrenia spectrum diagnosis (F20 - F29 according to International Classification of Diseases Tenth Revision ICD-10), hospitalized in the period June 1998 - June 2008 in Child and Adolescent Psychiatry Department was interviewed a mean 7.3 years after the index hospitalization. During interview data concerning course of illness after discharge and present level of functioning were obtained. For 50 of the patients with available results of baseline assessment with Positive and Negative Syndrome Scale these data were also analyzed.ResultsMean age at the index hospitalization was 16.9 years, mean age at the follow-up assessment 24,3 years. Psychotropic drugs were currently receiving 72% of patients. In some kind of educational or vocational activity were engaged 68% of patients. Mortality rate was 2%. Baseline diagnosis of schizophrenia was associated with higher number of hospitalizations, current pharmacotherapy and lower probability of being in romantic relationship. Negative symptoms present during index hospitalization were associated with more intensive further treatment, but not with the current level of functioning.ConclusionsBaseline diagnosis and baseline level of negative symptoms were associated with mental health services utilization but had little impact on functional outcome.