bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tetrahedra Modification of Phosphates for Optical Anisotropy Enhancement
Authors: Qiu Haotian , An Ran , Li Junjie , Yang Zhihua , Pan Shilie , Mutailipu Miriding 
Published: August 2024

AbstractAs an exceptional optical gene, the [PO4] tetrahedron is indispensable in the field of optical crystals due to its gain in the band gap of solid materials. However, the high symmetry of [PO4] tetrahedron hinders the achievement of large optical anisotropy in the lattice for phosphate crystal forms. In this work, the heteroleptic tetrahedra strategy, which involves replacing some of the oxygen atoms on regular oxy‐tetrahedra, is proven to be a feasible approach for preserving the wide transmission of the original [PO4] tetrahedra and improving the polarizability anisotropy. Based on this, eight methylphosphates are designed and synthesized for the phosphate system by substituting a [CH3] group for the O atom on the [PO4] tetrahedra. Theoretically, as compared to [PO4] units, [CH3PO3] and [CH3PO3H] units can improve the polarizability anisotropy, particularly [CH3PO3H] units, which have the potential to be birefringence‐active. The strong birefringence (exp. 0.108@546.1 nm) and short deep‐UV cutoff edge (195 nm) of nonmetallic methylphosphates [C(NH2)3][CH3PO3H] in the series suggest that it may be a possible short‐wave UV birefringent crystal. In addition to providing new birefringence‐active units for optical material design, this study validates the viability of modifying tetrahedra to improve inherent short board of nearly rigid [PO4] tetrahedra in phosphate family.
Retina‐Like Neuromorphic Visual Sensor for Sensing Broad‐Spectrum Ultraviolet Light
Authors: Xi Zhaoying , Liu Maosheng , Zhang Jia‐Han , Zhang Shaohui , Li Lei , Li Shan , Jiang Mingming , Tang Weihua , Liu Zeng 
Published: August 2024

AbstractThe rapidly developing Artificial Intelligence era has an increasing demand for high‐performance organ‐on‐a‐chip systems, especially the vision system, which is the most essential perceptual system for human beings. However, traditional artificial vision systems require multiple functional components, which are not favorable for integration. Neuromorphic visual sensors (NVSs) inspired by the human retina combine visual sensing and multiple preprocessing functions. However, most NVSs require complex structures to achieve both photo sensing and memory, and are difficult to be large‐scale fabricated. Here, a novel In2O3‐Ga2O3 (InGaO) thin‐film‐based NVS with both high photosensitivity and superior photomemory performance is proposed, which can avoid the complex multilayer structure. The device possesses high accuracy optical communication and multiple retina‐like functions. Notably, this InGaO NVS achieves sensing of most UV light, and it has been experimentally confirmed to have excellent photoelectric synaptic performance under both 254 nm and 365 nm UV illumination. This work provides a feasible strategy to assist the human eye in sensing invisible UV light.
Cellular Uptake of Phase‐Separating Peptide Coacervates
Authors: Shebanova Anastasia , Perrin Quentin Moana , Zhu Kexin , Gudlur Sushanth , Chen Zilin , Sun Yue , Huang Congxi , Lim Zhi Wei , Mondarte Evan Angelo , Sun Ruoxuan , Lim Sierin , Yu Jing , Miao Yansong , Parikh Atul N. , Ludwig Alexander , Miserez Ali 
Published: August 2024

AbstractPeptide coacervates self‐assembling via liquid‐liquid phase separation are appealing intracellular delivery vehicles of macromolecular therapeutics (proteins, DNA, mRNA) owing to their non‐cytotoxicity, high encapsulation capacity, and efficient cellular uptake. However, the mechanisms by which these viscoelastic droplets cross the cellular membranes remain unknown. Here, using multimodal imaging, data analytics, and biochemical inhibition assays, we identify the key steps by which droplets enter the cell. We find that the uptake follows a non‐canonical pathway and instead integrates essential features of macropinocytosis and phagocytosis, namely active remodeling of the actin cytoskeleton and appearance of filopodia‐like protrusions. Experiments using giant unilamellar vesicles show that the coacervates attach to the bounding membrane in a charge‐ and cholesterol‐dependent manner but do not breach the lipid bilayer barrier. Cell uptake in the presence of small molecule inhibitors – interfering with actin and tubulin polymerization – confirm the active role of cytoskeleton remodeling, most prominently evident in electron microscopy imaging. These findings suggest a peculiar internalization mechanism for viscoelastic, glassy coacervate droplets combining features of non‐specific uptake of fluids by macropinocytosis and particulate uptake of phagocytosis. The broad implications of this study will enable to enhance the efficacy and utility of coacervate‐based strategies for intracellular delivery of macromolecular therapeutics.
FOXO1‐NCOA4 Axis Contributes to Cisplatin‐Induced Cochlea Spiral Ganglion Neuron Ferroptosis via Ferritinophagy
Authors: Wang Xue , Xu Lei , Meng Yu , Chen Fang , Zhuang Jinzhu , Wang Man , An Weibin , Han Yuechen , Chu Bo , Chai Renjie , Liu Wenwen , Wang Haibo 
Published: August 2024

AbstractMammalian cochlea spiral ganglion neurons (SGNs) are crucial for sound transmission, they can be damaged by chemotherapy drug cisplatin and lead to irreversible sensorineural hearing loss (SNHL), while such damage can also render cochlear implants ineffective. However, the mechanisms underlying cisplatin‐induced SGNs damage and subsequent SNHL are still under debate and there is no currently effective clinical treatment. Here, this study demonstrates that ferroptosis is triggered in SGNs following exposure to cisplatin. Inhibiting ferroptosis protects against cisplatin‐induced SGNs damage and hearing loss, while inducing ferroptosis intensifies these effects. Furthermore, cisplatin prompts nuclear receptor coactivator 4 (NCOA4)‐mediated ferritinophagy in SGNs, while knocking down NCOA4 mitigates cisplatin‐induced ferroptosis and hearing loss. Notably, the upstream regulator of NCOA4 is identified and transcription factor forkhead box O1 (FOXO1) is shown to directly suppress NCOA4 expression in SGNs. The knocking down of FOXO1 amplifies NCOA4‐mediated ferritinophagy, increases ferroptosis and lipid peroxidation, while disrupting the interaction between FOXO1 and NCOA4 in NCOA4 knock out mice prevents the cisplatin‐induced SGN ferroptosis and hearing loss. Collectively, this study highlights the critical role of the FOXO1‐NCOA4 axis in regulating ferritinophagy and ferroptosis in cisplatin‐induced SGNs damage, offering promising therapeutic targets for SNHL mitigation.
Enhancing Stability and Safety of Commercial Solid‐State Lithium Batteries Through Ternary Eutectic Solvents for Solid‐State Electrolyte Interface Modification
Authors: Zhou Kaixuan , Dai Xinke , Zhang Long , Liu Hongtao , Li Tong , Zhang Xiaoming , Wen Jiawei , Huang Guoyong , Xu Shengming 
Published: August 2024

AbstractSolid‐state polymerized electrolytes exhibit advantageous properties, making them optimal candidates for next‐gen commercial solid‐state batteries. However, these electrolytes present significant challenges in terms of long‐term cycling stability, energy density, and safety. In this study, a ternary eutectic solid electrolyte (TESE) is prepared by combining deep eutectic solvents (DESs), polyvinylidene fluoride‐hexafluoropropylene (PVDF‐HFP), and fluorinated ethylene carbonate (FEC). TESE also facilitates uniform lithium deposition, interfacial stability, and long‐cycle stability. N‐Methylacetamide in DESs preferentially occupies the lithium dissolution sheath, which in turn initiates a concentration gradient‐driven decomposition of FEC and stimulates the generation of inorganic solid electrolyte interphase (SEI) layers. The lithium metal and graphite soft pack full batteries are successfully assembled, demonstrating that Li/P‐0.8‐FEC/LFP exhibits excellent long‐cycle performance, with a capacity of 139.9 mAh g−1 after 500 cycles at 1 C 25 °C, accompanied by 97.8 % capacity retention. Furthermore, the Gr/P‐0.8‐FEC/LFP commercial solid‐state flexible pack full cell exhibits stable cycling performance at a high rate of 1 C. Moreover, the device exhibits remarkable safety in a series of rigorous safety tests, including 100 repeated bendings, pinning, 7100 N force extrusion, and cutting. The study results demonstrate that the electrolyte exhibits excellent cycling performance and safety characteristics, indicating significant potential for commercialization.
Unveiling the Crucial Role of Dissolved Fe2+ on the Solid Electrolyte Interphase in Long‐life LiFePO4/Graphite Batteries
Authors: Tang Shijun , Liang Yuli , Peng Yufan , Hu Yonggang , Liao Yiqing , Yang Xuerui , Zhang Huiyan , Lin Ying , Zhang Ke , Liang Jinding , Li Bowen , Zhao Guangjin , Wei Yimin , Gong Zhengliang , Yang Yong 
Published: August 2024

AbstractThe dissolution of iron from the cathode significantly contributes to the accelerated degradation of LiFePO4/Graphite batteries, particularly at elevated temperatures. However, a systematic understanding of the spatial distribution and impact of Fe ions on the dynamic solid electrolyte interphase (SEI) layer is lacking. In this study, a comprehensive and quantitative investigation is conducted into the effects of transition metals (TM) and thoroughly examined the interaction between dissolved Fe2+ and SEI in long‐life LiFePO4/Graphite pouch cells. The dissolved Fe in the electrolyte is more prone to deposition at the negative electrode at elevated temperatures, leading to an accelerated loss of active lithium. Additionally, Fe deposition on the SEI catalyzes the decomposition of EC and contributes to an increase in organic components, particularly lithium alkyl carbonates within the SEI, as evidenced by mass spectrometry titration (MST) analysis. Neutron imaging (NI) provides more insights into the impacts of dissolved Fe2+ on active lithium loss, SEI components, and electrolyte decomposition, resulting in greater macroscopic heterogeneity in the electrode regions of the cells. This research sheds light on the mechanisms underlying the degradation of LiFePO4/Graphite batteries and provides valuable insights for the development of strategies to mitigate capacity fade and enhance battery performance and longevity.
Surface Anticorrosion Engineering by Polyphosphate Oxyanions for Durable Seawater Oxidation
Authors: Wang Xunlu , Hu Huashuai , Song Junnan , Ma Junqing , Du Hanxiao , Wang Jiacheng Jayden , Wang Min , Chen Wei , Zhou Yin , Wang Jiacheng , Yang Minghui , Zhang Lingxia 
Published: August 2024

AbstractElectrolysis of seawater represents great potentials for sustainable hydrogen production. However, both competitive Cl− adsorption and catalysts corrosion caused by chlorine oxidation reaction (ClOR) are major challenges in seawater electrolysis. Inspired by the concept of hard and soft acids and bases (HSAB), polyphosphate oxyanions (P3O105−) on Ni(OH)2 surface is coordinated to obtain harder acid Ni sites, which could obtain 160 times stability enhancement compared to pure Ni(OH)2 for oxygen evolution reaction (OER) in alkaline seawater at 800 mA cm−2. Also, the turnover frequency value on Ni(OH)2‐P3O105− is 50 times that on Ni(OH)2, implying higher intrinsic OER activity of Ni(OH)2‐P3O105−. Theoretical and experimental investigations show that P3O105− could facilitate transition of Ni3+ to harder acid Ni>3+, thus preferring adsorption of hard base OH− rather than soft base Cl−. This could enhance OER selectivity and inhibit undesirable ClOR. Furthermore, molecular dynamics simulations indicate that the Cl− concentration near the electrode could be reduced by nearly half due to electrostatic repulsion of Cl− by surface P3O105− oxyanions. When assembled into an electrolyzer for alkaline seawater splitting, it could operate at 2.2 V with large current up to 1.4 A for 240 h.
Effects of potassium application on growth, yield, and quality of dryland cotton
Authors: Kommineni Varshith , Bhandari Ammar B. 
Published: August 2024

AbstractPotassium (K) deficiency reduces cotton (Gossypium hirsutum L.) growth, development, lint yield, and fiber quality. The study's objective was to compare the effects of K fertilizer rate on cotton plant height (CPH), yield, and fiber quality in three cotton cultivars. Three cotton cultivars studied were NG 5711 B3XF (C1), PHY 480 W3FE (C2), and FM 1953GLTP (C3). Granular K fertilizer was surface broadcast and incorporated 1 week before planting at 34, 50, and 67 kg ha−1. The CPH and canopy width were measured from 30 to 105 days after planting. The cotton CPH increased by 13%, 17%, and 12% in 2020 and by 6%, 4%, and 8% in 2021 with 34, 50, and 67 kg ha−1 K fertilizer rates compared to control. The K application increased cotton canopy width by 39% in 2021 compared to 2020. The K application at 50 kg ha−1 yielded significantly more cotton yield than the control in 2020. The cotton lint yield increased by 25%, 34%, and 9% in 2020 and by 4%, 17%, and 11% in 2021 with 34, 50, and 67 kg ha−1 K fertilizer application rates than control. The cotton fiber staple length and color grade increased significantly with the 50 kg ha−1 K application rate than the control in 2020. Cultivars significantly impacted Col‐Rd and Col‐b in 2020 and 2021. This study shows that fertilizer‐K application improves not only yield, but also staple length and color grade in rainfed cotton crops.
Facile and Metal‐Free Synthesis of Isoflavones Using α‐Aryl‐β,β‐Ditosyloxy Ketones
Authors: Bains Omkar , Kumar Ashish , Kamal Raj , Kumar Ravinder , Kumar Rajesh , Rom Tanmay , Kumar Paul Avijit 
Published: August 2024

AbstractConsidering the drawbacks associated with available synthetic methodologies of isoflavones, herein we have reported a metal‐free and eco‐friendly approach to these natural products. In the present study, we have carried out the synthesis of eight isoflavone derivatives 7a–7h using α‐aryl‐β,β‐ditosyloxy ketone protocol. Initially, we have protected the 2’‐hydroxy group of respective chalcone moiety in order to remove its interference under reaction conditions. The protected chalcones were then subjected to 1,2‐aryl migration by being treated with hydroxy(tosyloxy)iodobenzene (HTIB) reagent in a non‐nucleophilic solvent (CH2Cl2). This migration furnished the formation of α‐aryl‐β,β‐ditosyloxy ketones via C−C bond formation from their corresponding chalcones in moderate to good yields (55–82 %). The ambiguity regarding the exact molecular structure of the α‐aryl‐β,β‐ditosyloxy ketones was examined through the single crystal X‐ray diffraction data. At last, the synthesis of isoflavones was carried out in moderate to good yields (50–80 %) by performing the reaction of α‐aryl‐β,β‐ditosyloxy ketones with sodium hydroxide in aqueous methanol.
Research Progress of Femtosecond Laser‐Printed Perovskite Quantum Dots in Amorphous Glass
Authors: Xiao Han , Zeng Lingwei , Lei Lei , Chen Daqin 
Published: August 2024

AbstractLead halide perovskite quantum dots (PeQDs) have garnered increasing attention due to their extraordinary optoelectronic properties. In recent years, femtosecond (fs) laser direct writing shows to be an effective way of inducing localized crystallization of PeQDs inside glass matrix while remaining their structural stability and optical performance. This article reviews the research progress on fs laser irradiation‐induced nucleation/growth of PeQDs in glass and discusses the latest advancements in the use of the technology for optical data storage, micrometer‐scale light‐emitting diode (LED), information security protection, and other related fields. It offers novel insights and perspectives for exploring new functionality and device application of fs laser‐printed PeQDs glass composite structures.
Quantum Correlation Enhanced with Quantum Coherent Feedback Control in a Cavity‐magnon Hybrid System
Authors: Lin Yue‐Han , Lin Ya‐Qin , Lin Zhi‐Ying , Yang Rong‐Can , Liu Hong‐Yu 
Published: August 2024

AbstractA scheme is proposed to enhance quantum correlation, including entanglement and steering, for two magnon modes in a cavity‐magnon hybrid system through coherent quantum feedback. The hybrid system consists of a microwave cavity and two YIG spheres, which incorporates a nonlinear flux‐driven Josephson parametric amplifier in order for the generation of two photons within the cavity simultaneously. A quantum coherent feedback loop is used for the reduction of effective dissipation. By modulating feedback parameters, optimal bipartite and tripartite entanglement, as well as quantum steering are derived. Importantly, compared with the same setup without coherent feedback, the proposed scheme significantly improves quantum correlation. Furthermore, by optimizing the feedback reflectivity and the ratio of cavity‐magnon coupling strength, the enhancement of asymmetric steering can be controlled. Notably, incorporating the feedback loop effectively increase its robustness against thermal noise, thus the scheme offer better prospect for experimental development. This study paves the way for advancements in quantum information processing and quantum entanglement within cavity‐magnonics.
Phenanthrene Appending Ruthenium Complexes: DNA Binding, Molecular Docking, TDDFT Calculation, and Photocytoxicity In Vitro
Authors: Liu Xue‐Wen , Ma Liang , He Geng‐Jun , Hu Xia , Chen Yuan‐Dao , Jin Jun‐Ling , Zhang Song‐Bai 
Published: August 2024

ABSTRACTPhotodynamic therapy (PDT) has been an effective tumor treatment to reduce the side effects of chemotherapy. Herein, we described the synthesis of two Ru (II) complexes by introducing a phenanthrene unit and their photocytotoxicity. Ru1 and Ru2 displayed high DNA affinities by intercalation. Under light, two complexes produced high singlet oxygen (1O2) quantum yields and cleaved DNA efficiently. Both high DNA affinities and 1O2 quantum yields of two complexes resulted in obvious photocytotoxicity towards Hela, A549, and A375 cells. Furthermore, low dark cytotoxicity was also observed for two complexes, which may promote them to act as potential PDT agents. TDDFT (Time‐dependent density functional theory) calculations also demonstrated two complexes that might display the PDT activities via 1O2 photogeneration.
Comparative Study of High Voltage Spinel∥Lithium Titanate Lithium‐ion Batteries in Ethylene Carbonate Free Electrolytes
Authors: Stokes‐Rodriguez Killian , Jayasayee Kaushik , Hanetho Sidsel M. , Kvello Jannicke , P. Molesworth Peter , Dahl Øystein , Peter Wagner Nils 
Published: August 2024

AbstractA persistent obstacle towards the realization of high voltage cathodes is electrolyte instability where oxidation and transition metal dissolution manifest in rapid capacity failure with both issues connected to the presence of ethylene carbonate in the electrolyte. Here, alternative electrolyte co‐solvents are investigated and compared, where the cyclic carbonate is replaced with sulfones ethyl methyl sulfone (EMS) and tetra methylene sulfone (TMS) and fluoroethylene carbonate (FEC). The best full cell performance was observed for cells cycled in a FEC/EMC (3/7) and FEC/EMC (1/1) electrolytes which exhibited 84–85 % capacity retention after 500 cycles. TMS/EMC (3/7), was determined to be the best performing sulfone electrolyte and maintained 71 % capacity after 500 cycles. Post‐mortem XPS analysis indicated different film forming mechanisms for the respective co‐solvent. A thicker cathode electrolyte interphase (CEI) on the LNMO was observed for the FEC containing electrolytes (relative to when TMS was used as the co‐solvent) indicating more effective passivation of the reactive cathode surface which correlated well with the enhanced cycling stability observed. For LTO, more evidence of transition metal migration and a thicker solid electrolyte interphase (SEI) layer was observed for the sulfone electrolyte suggesting more parasitic anode‐electrolyte interactions and an inability to mitigate Mn2+/Ni2+ crosstalk.
Molecular mechanisms of natural antifreeze phenomena and their application in cryopreservation
Authors: Shi Lingyu , Zang Chuanbao , Liu Zhicheng , Zhao Gang 
Published: August 2024

AbstractCryopreservation presents a critical challenge due to cryo‐damage, such as crystallization and osmotic imbalances that compromise the integrity of biological tissues and cells. In contrast, various organisms in nature exhibit remarkable freezing tolerance, leveraging complex molecular mechanisms to survive extreme cold. This review explores the adaptive strategies of freeze‐tolerant species, including the regulation of specific genes, proteins, and metabolic pathways, to enhance survival in low‐temperature environments. We then discuss recent advancements in cryopreservation technologies that aim to mimic these natural phenomena to preserve cellular and tissue integrity. Special focus is given to the roles of glucose metabolism, microRNA expression, and cryoprotective protein modulation in improving cryopreservation outcomes. The insights gained from studying natural antifreeze mechanisms offer promising directions for advancing cryopreservation techniques, with potential applications in medical, agricultural, and conservation fields. Future research should aim to further elucidate these molecular mechanisms to develop more effective and reliable cryopreservation methods.
Jurors’ perceptions of transgender victims of sexual assault: A literature review of empirical research and policy review of judicial instructions
Authors: Ribeiro Gianni , Nitschke Faye T. 
Published: August 2024

AbstractSexual assault affects many people of all gender identities, yet most cases do not result in conviction. This may be due to common, inaccurate misperceptions juries hold about how sexual assault is perpetrated and how victims respond to sexual assault. Research has examined misperceptions relating to cisgender victims, yet little is known about the unique misconceptions and stereotypes that may unfairly disadvantage transgender victims or whether courts are attempting to safeguard against them. This article presents a literature review of empirical research on (mock) jurors’ perceptions of transgender victims and a review of judicial instructions about gender identity. We find that empirical research is extremely limited with mixed findings, but many jurisdictions allow for judicial instructions warning jurors against prejudice based on gender identity. Further research is urgently needed to identify common misperceptions jurors may have that are specific to transgender victims to inform legal safeguards and improve justice outcomes.
Flecainide toxicity—Clinical diagnosis and management of an urgent condition
Authors: Bazoukis George , Efthymiou Polyxeni , Yiannikourides Andronicos , Khattab Elina , Dimitriades Varnavas , Tse Gary , Pavlou Marios , Georgiou Panagiota , Kapetis Lorentzos , Patestos Dimitrios , Tsielepis Michalis , Myrianthopoulos Kimon , Papasavvas Elias , Christophides Theodoros 
Published: August 2024

Key Clinical MessageClinical suspicion, clinical presentation, and electrocardiogram can help clinicians diagnose flecainide toxicity. Currently, there are no guidelines for the management of patients with flecainide toxicity. Sodium bicarbonate, lipid emulsion therapy, and extracorporeal life support have been used in this setting. Amiodarone and lidocaine can be used for the management of wide QRS complex tachycardias in hemodynamically stable patients with flecainide toxicity.
Stone heart syndrome: A curious case of digoxin toxicity and calcium infusion
Authors: Hussein Guleid , Krastev Peter , Mallari Arvin Junn P. , El Labban Mohamad , Yadav Sumeet , Hassan Mohamed , Warsame Mohamed , Zoesch Greta , Trnka John , Vojjala Nikhil , Jain Shika M. , Surani Salim , Khan Syed Anjum 
Published: August 2024

Key Clinical MessageStone heart syndrome has a complex interaction with digoxin toxicity, where, theoretically, the administration of intravenous calcium can worsen a patient's condition. Research on this subject is conflicting, so it is imperative to approach it cautiously.