bluuebunny/crossref_metadata_2025_split huggingface dataset:
Interseismic megathrust coupling beneath the Nicoya Peninsula, Costa Rica, from the joint inversion of InSAR and GPS data
Authors: Xue Lian , Schwartz Susan , Liu Zhen , Feng Lujia 
Published: April 2015

AbstractThe Nicoya Peninsula, Costa Rica, was struck by a long‐anticipated and gap‐filling Mw 7.6 earthquake in 2012. To study interseismic strain accumulation on the megathrust beneath the Nicoya Peninsula, we present an improved interseismic coupling model by integrating interferometric synthetic aperture radar (InSAR) and GPS data. Our model reveals three strongly coupled patches. The first strongly coupled patch locates beneath the Nicoya Peninsula and ruptured during the 2012 earthquake. The second strongly coupled patch locates offshore the central Nicoya Peninsula and remained largely unbroken. However, this region is close to and possibly intermingled with shallow slow slip and tremor, suggesting that accumulated strain in this region may be released both seismically and aseismically. The third strongly coupled patch offshore of the southeastern end of Nicoya overlaps part of the coseismic rupture of the 1990 Mw 7.0 Nicoya Gulf earthquake, indicating that significant strain has re‐accumulated since this event. Incorporating InSAR data provides a more refined interseismic coupling model than using GPS alone and allows for a more reliable comparison with local seismic and aseismic activities. This comparison indicates that strongly locked regions during the interseismic stage are the loci of coseismic slip, and deep slow slip and low‐frequency earthquakes occur in regions of low coupling or transition zones from low to high coupling, while shallow slow slip and tremor commingle with strongly coupled regions. Our study demonstrates that InSAR data can be used to recover small long‐wavelength deformation signals with refined resolution in challenging subduction zone environments when integrated with GPS observations.
Innovation, adaptation and technology as habitus: the origins of alluvial gold mining methods in Australia
Authors: Lawrence Susan , Davies Peter 
Published: April 2015

AbstractThe introduction of Cornish mining methods during the Australian gold rush provides a case study for examining the role of technological innovation in the context of migration. New physical and social environments encountered as a result of migration force migrants to adapt familiar technologies to their new circumstances. Cornish migrants to Australia were able to apply their knowledge of traditional methods for working alluvial tin deposits to the exploitation of alluvial gold. These methods were heavily dependent on reliable sources of water, and in order to ensure success, the miners developed innovative technical and legal systems for managing water supplies.
Evidence for Pleistocene seed grinding at Lake Mungo, south‐eastern Australia
Authors: Fullagar Richard , Hayes Elspeth , Stephenson Birgitta , Field Judith , Matheson Carney , Stern Nicola , Fitzsimmons Kathryn 
Published: April 2015

AbstractGrinding stones and fragments have often been found in archaeological sites at Lake Mungo, south‐western New South Wales, and their function has mostly been inferred on the basis of grindstone morphology. Of particular interest has been the antiquity of grass seed grinding, which is usually associated with deeply grooved, large sandstone dishes. Previous studies of grinding stones from the region have found no compelling evidence for seed grinding prior to the Pleistocene/Holocene boundary. One of the problems has been that the grinding stones have been found on deflated surfaces and have been difficult to accurately provenance and date. Here, we report a functional study of 17 sandstone artefacts, recently collected from the central part of the Mungo lunette, where a suite of OSL ages have provided bracketing age estimates for the stratigraphic units. Ten artefacts are attributed to Unit E deposited between c.25 and 14 ka. Four artefacts are attributed to Unit F, deposited c.8 ka. Three artefacts from the Golgol lag are of unknown age. Usewear indicates a likely seed grinding function for 14 of the artefacts. Use‐related residues include starch, cellulose and collagen. The results of this study provide additional support for Pleistocene plant processing and seed grinding activities in Sahul.
President's page
Authors: Bruce Harry 
Published: April 2015

EDITOR'S SUMMARYMember and business concerns, project updates and future plans will be addressed during the annual ASIS&T Board of Directors’ summer retreat at the end of July 2014. This is an opportunity for Board members to report as liaisons for committees and task forces, with appreciation for their important contributions to the Association. The Board will continue its focus on membership engagement, drawing feedback from member surveys and interviews and exploring opportunities to enhance membership interaction throughout the year. Members and consultants will report progress to promote those goals through the social media and website redesign initiatives. The Board will also critically evaluate issues related to the ASIS&T Annual Meeting, from its length and structure to perceptions of value by members and guests. The President expresses gratitude to the Board members for their volunteer efforts stewarding the Association and leading preparations for the Annual Meeting in Seattle.
Research data management on a shoestring budget
Authors: Henderson Margaret , Raboin Regina , Shorish Yasmeen , Van Tuyl Steve 
Published: April 2015

EDITOR'S SUMMARYIn response to mandates from the federal government, many academic librarians face a new challenge to become service providers for research data management. A panel at RDAP14 convened representatives from Virginia Commonwealth University, James Madison University and a collaboration of seven New England libraries to discuss their strategies in response to the regulations when faced with limited resources. A common theme was to take advantage of work already done by others, including faculty surveys and existing data management resources such as DMPTool and Data Curation and Profiles Toolkit. Spreading the word on data issues to spark collaboration and gaining the support of library administration are key. Positive response from stakeholders can provide momentum to request additional resources and provide instruction on data management planning.
NSF datanet partners update
Authors: Akmon Dharma 
Published: April 2015

EDITOR'S SUMMARYAttendees at the 2014 Research Data Access and Preservation Summit (RDAP14) heard an update on the DataNet project, funded by the National Science Foundation (NSF) and designed to bring together data research infrastructure organizations to support digital preservation, access, integration and analysis. Five project partners have received funding, each convening collaborating institutions and pursuing group goals. DataONE focuses on data preservation and metadata, distributed storage, usability and assessment, educational outreach, data discovery and interoperability. SEAD (Sustainable Environment Actionable Data) seeks to build a cyberinfrastructure for sustainability science, providing a repository, researcher network and virtual archive. Tools developed by Terra Populus will enable users to extract data from different sources to create custom combinations. The goal of the DataNet Federation Consortium is to support collaborative research and federated collections by putting together a national data infrastructure with client‐friendly metadata templates and bulk uploading to support long‐term management. The DataNet partners continue separate lines of research to build an effective cyberinfrastructure that will support sharing and preserving diverse scientific studies.
Learning to curate
Authors: Doty Jennifer , Herndon Joel , Lyle Jared , Stephenson Libbie 
Published: April 2015

EDITOR'S SUMMARYThree data specialists reviewed their experiences learning about and applying the Inter‐university Consortium for Political and Social Research (ICPSR) processes and tools for curating research data. A small virtual community discussed curation theories on data acquisitions, review, processing, metadata and dissemination and shared progress implementing the ICPSR workflows and tools. Curators at Duke University, dealing with data on political donors, found processing obstacles from incomplete and mismatched data and faced confidentiality questions. At Emory University, gaps in coded data on home schooling practices revealed problems arising from lack of preplanning for long‐term archiving and research and the need to clarify data needs for later re‐use. By applying ICPSR processes, curators at UCLA's Social Sciences Data Archive were able to improve their workflow and understand the work necessary for open archiving. All participants gained from the opportunity to practice ICPSR curation practices, realized the resource demands and saw the value librarians can provide by consulting with faculty on data management and preservation.
Regulation of macroautophagy in amiodarone‐induced pulmonary fibrosis
Authors: Mahavadi Poornima , Knudsen Lars , Venkatesan Shalini , Henneke Ingrid , Hegermann Jan , Wrede Christoph , Ochs Matthias , Ahuja Saket , Chillappagari Shashi , Ruppert Clemens , Seeger Werner , Korfei Martina , Guenther Andreas 
Published: April 2015

AbstractAmiodarone (AD) is an iodinated benzofuran derivative, especially known for its antiarrhythmic properties. It exerts serious side‐effects even in patients receiving low doses. AD is well‐known to induce apoptosis of type II alveolar epithelial cells (AECII), a mechanism that has been suggested to play an important role in AD‐induced lung fibrosis. The precise molecular mechanisms underlying this disease are, however, still unclear. Because of its amphiphilic nature, AD becomes enriched in the lysosomal compartments, affecting the general functions of these organelles. Hence, in this study, we aimed to assess the role of autophagy, a lysosome‐dependent homeostasis mechanism, in driving AECII apoptosis in response to AD. In vitro, AD‐treated MLE12 and primary AECII cells showed increased proSP‐C and LC3B positive vacuolar structures and underwent LC3B‐dependent apoptosis. In addition, AD‐induced autophagosome‐lysosome fusion and increased autophagy flux were observed. In vivo, in C57BL/6 mice, LC3B was localised at the limiting membrane of lamellar bodies, which were closely connected to the autophagosomal structures in AECIIs. Our data suggest that AD causes activation of macroautophagy in AECIIs and extensive autophagy‐dependent apoptosis of alveolar epithelial cells. Targeting the autophagy pathway may therefore represent an attractive treatment modality in AD‐induced lung fibrosis.
Developmental pathways of motor dysfunction
Authors: Kleven Gale A. , Bellinger Seanceray A. 
Published: April 2015

ABSTRACTRecent evidence has revealed unique patterns of behavioral development after prenatal insult similar to those outlined in studies of adult metabolic dysfunction after prenatal malnutrition. The hallmark features of this Developmental Pathway include a prenatal insult to the nervous system (environmental or genetic) followed by a period of Silent Vulnerability, where no or few functional deficits are observed, and finally emergence of later dysfunction. Possible mechanisms leading to later dysfunction from prenatal insult may include secondary or cascade effects due to the timing of prenatal insults relative to later developing structures in the brain. Methods best employed to study the mechanisms of these pathways are microgenetic and longitudinal designs that include behavioral assessment during the prenatal period of development, and animal models such as the guinea pig. © 2015 Wiley Periodicals, Inc. Dev Psychobiol 57: 435–446, 2015.
Episodic memory and future thinking during early childhood: Linking the past and future
Authors: Cuevas Kimberly , Rajan Vinaya , Morasch Katherine C. , Bell Martha Ann 
Published: April 2015

ABSTRACTDespite extensive examination of episodic memory and future thinking development, little is known about the concurrent emergence of these capacities during early childhood. In Experiment 1, 3‐year‐olds participated in an episodic memory hiding task (“what, when, where” [WWW] components) with an episodic future thinking component. In Experiment 2, a group of 4‐year‐olds (including children from Experiment 1) participated in the same task (different objects and locations), providing the first longitudinal investigation of episodic memory and future thinking. Although children exhibited age‐related improvements in recall, recognition, and binding of the WWW episodic memory components, there were no age‐related changes in episodic future thinking. At both ages, WWW episodic memory performance was higher than future thinking performance, and episodic future thinking and WWW memory components were unrelated. These findings suggest that the WWW components of episodic memory are potentially less fragile than the future components when assessed in a cognitively demanding task. © 2015 Wiley Periodicals, Inc. Dev Psychobiol 57: 552–565, 2015.
Variation among individuals in photoperiod responses: Effects of breeding schedule, photoperiod, and age‐related photoperiodic experience in birds
Authors: Watts Heather E. , MacDougall‐Shackleton Scott A. , Hahn Thomas P. 
Published: April 2015

ABSTRACTMany organisms use environmental cues to regulate reproductive function in order to time reproduction to coincide with favorable environmental conditions. Whereas we understand much about how environmental cues are used to time reproduction, we know relatively little about variation among individuals in responsiveness to environmental cues. However, this variation among individuals may represent a crucial component of a population's capacity to respond to changing environmental conditions. In this study, we quantify variation among individuals in photoperiod responsiveness of the avian reproductive system and investigate three potential underlying sources of this variation in environmental cue responsiveness. Specifically, we tested whether age‐related photoperiodic experience, strength of the photoperiodic cue (day length), and degree of flexibility in breeding schedule influenced the degree of variation observed in experimental studies of seven species of cardueline finches. Overall, we found a high degree of variation among individuals in photoperiod response, and this was influenced by experimental photoperiod and breeding schedule. As experimental photoperiod became longer, the degree of variation declined. Opportunistic breeders showed greater variation in response compared with more seasonal breeders. We found no effect of age‐related photoperiodic experience in one species for which we could examine this factor. The results of this study highlight the extent to which individuals can vary in their response to environmental cues and point to both species ecology and characteristics of the cue as important influences on the degree of this variation. J. Exp. Zool. 323A: 368–374, 2015. © 2015 Wiley Periodicals, Inc.
Identification of a novel dehydration responsive gene, drp10, from the African clawed frog, Xenopus laevis
Authors: Biggar Kyle K. , Biggar Yulia , Storey Kenneth B. 
Published: April 2015

ABSTRACTDuring periods of environmental stress a number of different anuran species employ adaptive strategies to promote survival. Our study found that in response to dehydration (i.e., loss of total body water content), the African clawed frog (Xenopus laevis) increased the expression of a novel gene (drp10) that encodes a structural homolog of the freeze‐responsive FR10 protein found in wood frogs. Similar to FR10, the DRP10 protein was found to also contain a highly conserved N‐terminal cleavable signal peptide. Furthermore, DRP10 was found to have high structural homology to the available crystal structures of type A and E apolipoproteins in Homo sapiens, and a type IV LS‐12 anti‐freeze protein in the longhorn sculpin, Myoxocephalus octodecemspinosis. In response to dehydration, the transcript expression of drp10 was found to increase 1.52 ± 0.16‐fold and 1.97 ± 0.11‐fold in response to medium (15%) and high (30%) dehydration stresses in the liver tissue of X. laevis, respectively, while drp10 expression increased 2.12 ± 0.12‐fold and 1.46 ± 0.16‐fold in kidney tissue. Although the molecular function of both dehydration‐responsive DRP10 and the freeze‐responsive FR10 have just begun to be elucidated, it is likely that both are frog‐specific proteins that likely share a similar purpose during water‐related stresses. J. Exp. Zool. 323A: 375–381, 2015. © 2015 Wiley Periodicals, Inc.
What to compare and how: Comparative transcriptomics for Evo‐Devo
Authors: Roux Julien , Rosikiewicz Marta , Robinson‐Rechavi Marc 
Published: April 2015

ABSTRACTEvolutionary developmental biology has grown historically from the capacity to relate patterns of evolution in anatomy to patterns of evolution of expression of specific genes, whether between very distantly related species, or very closely related species or populations. Scaling up such studies by taking advantage of modern transcriptomics brings promising improvements, allowing us to estimate the overall impact and molecular mechanisms of convergence, constraint or innovation in anatomy and development. But it also presents major challenges, including the computational definitions of anatomical homology and of organ function, the criteria for the comparison of developmental stages, the annotation of transcriptomics data to proper anatomical and developmental terms, and the statistical methods to compare transcriptomic data between species to highlight significant conservation or changes. In this article, we review these challenges, and the ongoing efforts to address them, which are emerging from bioinformatics work on ontologies, evolutionary statistics, and data curation, with a focus on their implementation in the context of the development of our database Bgee (http://bgee.org). J. Exp. Zool. (Mol. Dev. Evol.) 324B: 372–382, 2015. © 2015 The Authors. J. Exp. Zool. (Mol. Dev. Evol.) published by Wiley Periodicals, Inc.
MRI interactions of a fully implantable pressure monitoring device
Authors: Stehlin Ellyce F. , McCormick Daniel , Malpas Simon C. , Pontré Beau P. , Heppner Peter A. , Budgett David M. 
Published: April 2015

PurposeTo investigate the potential patient risk and interactions between a prototype implantable pressure monitoring device and a 3T clinical magnetic resonance imaging (MRI) machine to guide device design towards MR Conditional safety approval.Materials and MethodsThe pressure monitor device contained a catheter‐mounted piezo‐resistive pressure sensor, rechargeable battery, wireless communication system, and inductive pickup coil. Standard testing methods were used to guide experiments to investigate static field induced force and torque, radiofrequency (RF)‐induced heating, image artifacts, and the MR's effect on device function. The specific clinical application of intracranial pressure monitoring was considered. RF‐induced heating experiments were supported by numerical modeling of the RF body coil, the device, and experimental phantom.ResultsSensing catheter lead length and configuration was an important component of the device design. A short 150 mm length catheter produced a heating effect of less than 2°C and a long 420 mm length catheter caused heating of 7.2°C. Static magnetic field interactions were below standard safety risk levels and the MR did not interfere with device function; however, artifacts have the potential to interfere with image quality.ConclusionInvestigation of MR interactions at the prototype stage provides useful implantable device design guidance and confidence that an implantable pressure monitor may be able to achieve MR Conditional safety approval. J. Magn. Reson. Imaging 2015;42:1441–1449.
A Preliminary Study of an Internet‐Based Intervention for OEF/OIF Veterans Presenting for VA Specialty PTSD Care
Authors: Belsher Bradley E. , Kuhn Eric , Maron David , Prins Annabel , Cueva David , Fast Elsbeth , France Deborah 
Published: April 2015

AbstractThis preliminary study sought to evaluate the feasibility and potential effectiveness of a cognitive–behavioral, web‐based intervention for posttraumatic stress in Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) veterans who are not able to participate, or not eligible to participate, in evidence‐based posttraumatic stress disorder (PTSD) treatments. The study used an uncontrolled pre‐posttest design with a sample of 24 OEF/OIF veterans presenting to a VA PTSD specialty clinic. Participants used the afterdeployment.org, Post‐Traumatic Stress (PTS) Workshop, which was supplemented with brief weekly telephone calls. Half of the participants (n = 12) completed at least 5 of the 8 workshop sessions. At posttreatment, 40.0% of completers demonstrated reliable reductions on PTSD symptoms and overall d = 1.04. Treatment satisfaction and acceptability was generally positive based on Likert ratings. This web‐based intervention for PTS appears to be a feasible and potentially helpful intervention for veterans who may not otherwise receive psychosocial interventions. Given the minimal resources required and the potential reach, this web‐based intervention could be a viable addition to services provided to OEF/OIF veterans seeking PTSD specialty care. Efforts to further develop and more rigorously evaluate this approach are warranted.
Trauma‐Related Guilt: Conceptual Development and Relationship With Posttraumatic Stress and Depressive Symptoms
Authors: Browne Kendall C. , Trim Ryan S. , Myers Ursula S. , Norman Sonya B. 
Published: April 2015

Despite high prevalence and concerning associated problems, little effort has been made to conceptualize the construct of posttraumatic guilt. This investigation examined the theoretical model of trauma‐related guilt proposed by Kubany and Watson (2003). This model hypothesizes that emotional and physical distress related to trauma memories partially mediates the relationship between guilt cognitions and posttraumatic guilt. Using path analysis, this investigation (a) empirically evaluated relationships hypothesized in Kubany and Watson's model, and (b) extended this conceptualization by evaluating models whereby guilt cognitions, distress, and posttraumatic guilt were related to posttraumatic stress disorder (PTSD) symptoms depression symptom severity. Participants were male U.S. Iraq and Afghanistan veterans (N = 149). Results yielded a significant indirect effect from guilt cognitions to posttraumatic guilt via distress, providing support for Kubany and Watson's model (β = .14). Findings suggested distress may be the strongest correlate of PTSD symptoms (β = .47) and depression symptoms (β = .40), and that guilt cognitions may serve to intensify the relationship between distress and posttraumatic psychopathology. Research is needed to evaluate whether distress specific to guilt cognitions operates differentially on posttraumatic guilt when compared to distress more broadly related to trauma memories.