bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Metal‐Free Radical Azidoarylation of Alkenes: Rapid Access to Oxindoles by Cascade C—N and C—C Bond‐Forming Reactions.
Authors: Matcha Kiran , Narayan Rishikesh , Antonchick Andrey P. 
Published: December 2013

AbstractThis new method for the oxidative radical azidation of alkenes relies on an azide in combination with a hypervalent iodine reagent.
ChemInform Abstract: Gold(I) or Silver Catalyzed Synthesis of α‐Indolylacrylates.
Authors: Pirovano Valentina , Facoetti Diego , Dell'Acqua Monica , Fontana Emanuela Della , Abbiati Giorgio , Rossi Elisabeth 
Published: December 2013

AbstractThe reaction of 2‐substituted indoles with 2‐acetamidoacrylate can be catalyzed by Au(I) or Ag(I) salts to afford the title compounds in good to moderate yields.
ChemInform Abstract: The Facile and Direct Formylation of Organoboron Aromatic Compounds with Benzodithiolylium Tetrafluoroborate.
Authors: Petruzziello Diego , Gualandi Andrea , Jaffar Hamza , Lopez‐Carrillo Veronica , Cozzi Pier Giorgio 
Published: December 2013

AbstractThe title reaction is accomplished from the commercially available carbenium ionic compound (II) without the use of transition metals.
ChemInform Abstract: Synthesis and Antioxidant Activity of a Novel Series of Pyrazolotriazine, Coumarin, Oxoazinone, and Pyrazinopyrimidine Derivatives.
Authors: Gouda Moustafa A. 
Published: December 2013

AbstractThe title compounds, synthesized using pyrazolyl nitrile (II) as key intermediate, are evaluated for their ABTS antioxidant activity.
ChemInform Abstract: Efficient, Green and Solvent‐Free Synthesis of Tetrasubstituted Imidazoles Using SbCl3/SiO2 as Heterogeneous Catalyst.
Authors: Safari Javad , Gandomi‐Ravandi Soheila , Naseh Simin 
Published: December 2013

AbstractA wide range of 1,2,4,5‐tetrasubstituted imidazoles (IV) (13 examples) are obtained in a four‐component cyclocondensation of 1,2‐diketone (I), aromatic aldehydes, primary aliphatic and aromatic amines, and ammonium acetate using silica‐supported SbCl3 as catalyst.
ChemInform Abstract: Synthesis of Functionalized Oxazoles via Silver‐Catalyzed Cyclization of Propargylamides and Allenylamides.
Authors: Hu Yancheng , Yi Ruxia , Wu Fan , Wan Boshun 
Published: December 2013

AbstractThe triethylamine‐promoted isomerization of propargylamides (I) to allenylamides followed by a silver‐catalyzed cyclization leads to a variety of 5‐vinyloxazoles [cf.
ChemInform Abstract: Synthesis and Antiviral Activity of New Substituted Methyl [2‐(Arylmethylene‐hydrazino)‐4‐oxo‐thiazolidin‐5‐ylidene]acetates.
Authors: Saeed Aamer , Al‐Masoudi Najim A. , Latif Muhammad 
Published: December 2013

AbstractThe title compounds (III) are obtained by cyclocondensation of thiosemicarbazones (I) with but‐2‐ynedioate (II) under solvent‐free microwave irradiation conditions.
ChemInform Abstract: Synthesis of 5‐Substituted 3‐Mercapto‐1,2,4‐triazoles via Suzuki—Miyaura Reaction.
Authors: Katkevica Sarmite , Salun Pavlo , Jirgensons Aigars 
Published: December 2013

Abstract3‐Bromo‐ (Ia) and 3‐iodo‐N,S‐dibenzyl‐5‐mercapto‐1,2,4‐triazoles (Ib) are utilized as versatile building blocks for Suzuki—Miyaura cross‐coupling reactions with aryl, vinyl‐, and heteroaryl boronic acid derivatives.
ChemInform Abstract: Synthesis and Biological Evaluation of Novel Benzimidazole Derivatives Bearing a Heterocyclic Ring at 4/5 Position.
Authors: Wubulikasimu Reyila , Yang Yanbing , Xue Fei , Luo Xianjin , Shao Dongping , Li Yuhuan , Gao Rongmei , Ye Weidong 
Published: December 2013

AbstractThe synthesis of a range of benzimidazole derivatives bearing heterocyclic rings is described by the employment of benzimidazole‐4/5‐carboxylic acid derivatives as substrates.
ChemInform Abstract: Unexpected Result for the Acylation of Arylhydrazonoethanethioamides.
Authors: Bolgova Anastasiya I. , Lugovik Kseniya , Subbotina Julia O. , Slepukhin Pavel A. , Bakulev Vasiliy A. , Belskaya Nataliya P. 
Published: December 2013

AbstractThe acylation of arylhydrazonoethanethioamides containing a primary amino group does not yield the expected acylthioamides but 5‐acylimino‐1,2,3‐thiadiazoles.
ChemInform Abstract: New Green, Recyclable Magnetic Nanoparticles Supported Amino Acids as Simple Heterogenous Catalysts for Knoevenagel Condensation.
Authors: Girija D. , Bhojya Naik H. S. , Kumar B. Vinay , Sudhamani C. N. , Harish K. N. 
Published: December 2013

AbstractIron oxide supported amino acid as recoverable catalyst is applied in Knoevenagel condensation leading to different substituted coumarin derivatives.
ChemInform Abstract: Silica Sulfuric Acid‐Catalyzed One‐Pot Synthesis, Mechanism, and Fluorescence Properties of 2‐(2‐Arylquinolin‐4‐(1H)‐ylidene)malononitriles.
Authors: Wan Yu , Lin Wei , Xin Hai‐qiang , Yuan Rui , Zhao Ling‐ling , Shi Jing‐jing , Wang Chao , Zhang Xiao‐xiao , Wu Hui 
Published: December 2013

AbstractA novel domino reaction between aminoacetophenone (I), malononitrile (II), and aromatic aldehydes (III) yields the title compounds (IV).
ChemInform Abstract: Microwave Promoted One‐Pot Synthesis of Some Novel N‐Aryl Isoquinoline Derivatives.
Authors: Havaldar Freddy H. , Mule Ganesh B. , Dabholkar Bhushan V. 
Published: December 2013

AbstractThe isoquinolines are synthesized by a direct one‐pot process under thermal and microwave conditions.
ChemInform Abstract: A Cascade Coupling Strategy for One‐Pot Total Synthesis of β‐Carboline and Isoquinoline‐Containing Natural Products and Derivatives.
Authors: Zhu Yan‐Ping , Liu Mei‐Cai , Cai Qun , Jia Feng‐Cheng , Wu An‐Xin 
Published: December 2013

AbstractThe title reaction allows the efficient synthesis of natural products such as eudistomins (IIIb) and (VIa), pityiacitrin (IIIe), and papaveraldine (IXb) as well as structurally related analogues.
ChemInform Abstract: A Facile and Expeditious Microwaves‐Assisted Synthesis of Furo[3,4‐b]indeno[2,1‐f]quinolin‐1‐one Derivatives via Multicomponent Reaction.
Authors: Peng Ju‐Hua , Jia Run‐Hong , Ma Ning , Zhang Ge , Wu Fei‐Yue , Cheng Chuang , Tu Shu‐Jiang 
Published: December 2013

AbstractThis rapid and direct method offers a simple route for the one‐pot, three‐component synthesis of highly functionalized fused heterocycles in high yields.
ChemInform Abstract: Synthesis of New Pyrimidinylaminobenzene Derivatives and Their Antiproliferative Activities Against Melanoma Cell Line.
Authors: Kim Hee Jin , Oh Chang‐Hyun , Yoo Kyung Ho 
Published: December 2013

AbstractDiaryl amide (I) and diaryl urea (II) derivatives possessing a pyrimidinylaminobenzene scaffold are synthesized and some of them are screened for their in vitro antiproliferative activities against A375P human melanoma cell line.
ChemInform Abstract: Synthesis, Characterization, and in vitro Antimicrobial Activity of a New Class of 7‐Substituted Amino‐2‐phenyl‐3H‐pyrimido[4,5‐d]pyrimidin‐4‐one.
Authors: Reddy B. Surendra , Reddy A. Babul , Reddy G. Ramachandra , Reddy P. Raveendra 
Published: December 2013

AbstractThe members of the new class of pyrimido pyrimidine derivatives (I) display pronounced in vitro antibacterial and antifungal activities.
ChemInform Abstract: Photoinduced and N‐Bromosuccinimide‐Mediated Cyclization of 2‐Azido‐N‐phenylacetamides.
Authors: Li Zhan‐Shan , Wang Wei‐Xia , Yang Ji‐Dong , Wu Yue‐Wei , Zhang Wei 
Published: December 2013

AbstractA synthesis of quinoxalin‐2‐ones or heterocyclic spiro compounds is developed using NBS‐promoted reactions of 2‐azido‐N‐phenylacetamides under visible light irradiation.
ChemInform Abstract: Synthesis and Biological Evaluation of a Series of Dithiocarbamates as New Cholinesterase Inhibitors.
Authors: Altintop Mehlika D. , Gurkan‐Alp A. Selen , Oezkay Yusuf , Kaplancikli Zafer A. 
Published: December 2013

AbstractThe title compounds (III) (10 examples) are obtained by treatment of benzyl chloride (II) with the appropriate sodium salt of N,N‐disubstituted dithiocarbamic acids (I).
ChemInform Abstract: Synthesis of Bis(1,2,2‐trichloroethyl) and Bis(dichlorovinyl) Selenides by Electrophilic Reaction of Selenium Dichloride with 1,2‐Dichloroethylene.
Authors: Martynov A. V. , Makhaeva N. A. , Larina L. I. , Amosova S. V. 
Published: December 2013

AbstractThe reaction of 1,2‐dichloroethylene (I) with selenium dichloride is studied.
ChemInform Abstract: Studies on the Reaction of 16‐Dehydropregnenolone Acetate (16‐DPA) with m‐Chloroperbenzoic Acid.
Authors: Ghosh Pranab , Subba Raju 
Published: December 2013

AbstractEpoxidation of 16‐DPA (I) with MCPBA on activated silica selectively leads to the 5,6‐epoxy derivative (II), whereas the reaction of (I) with MCPBA in solution gives the diepoxy derivative (III) as an isomeric mixture.
ChemInform Abstract: Synthesis of Branched Iminosugars Through a Hypervalent Iodine(III)‐Mediated Radical‐Polar Crossover Reaction.
Authors: Santana Andres G. , Paz Nieves R. , Francisco Cosme G. , Suarez Ernesto , Gonzales Conception C. 
Published: December 2013

AbstractStarting from readily available aldoses, anomeric key intermediates are formed in three steps [cf.
ChemInform Abstract: Methyl (3R,5R)‐3,5‐Dihydroxydecanoate in the Asymmetric Synthesis of Idea Leuconoe Pheromone and Formal Syntheses of (+)‐(3R,5R)‐3‐Hydroxydecano‐5‐lactone, Verbalactone, and Tolypothrix Pentaether.
Authors: Mineeva I. V. 
Published: December 2013

AbstractAn asymmetric synthesis of (IV) is outlined which is one of the numerous components of the abdominal gland secretion of the giant danaine butterfly idea leuconoe.
ChemInform Abstract: Synthesis of Azilsartan and Its Selected Potential Impurities.
Authors: Radl Stanislav , Cerny Josef , Stach Jan , Holec Jan , Pisa Ondrej , Gablikova Zuzana 
Published: December 2013

AbstractA reinvestigation of the angiotensin II AT1 receptor antagonist azilsartan (I) is conducted and the inconsistencies in the original references are explained.
ChemInform Abstract: Redox Reactions of Radionuclides
Authors: Perdicakis M. , Allard S. , Holgersson S. , Brian N. , Kay R. R. , Li N. , Stockdale A. , Baltrunas D. , Lujaniene G. , Schafer Th. , et al. et al. 
Published: December 2013

AbstractReview: 10 refs.
ChemInform Abstract: Recent Developments in Texaphyrin Chemistry and Drug Discovery
Authors: Preihs Christian , Arambula Jonathan F. , Magda Darren , Jeong Heeyeong , Yoo Dongwon , Cheon Jinwoo , Siddik Zahid H. , Sessler Jonathan L. 
Published: December 2013

AbstractReview: 65 refs.
p16INK4a overexpression and p16/Ki‐67 dual labeling versus conventional urinary cytology in the evaluation of urothelial carcinoma
Authors: Piaton Eric , Carré Christian , Advenier Anne‐Sophie , Decaussin‐Petrucci Myriam , Mège‐Lechevallier Florence , Lantier Philippe , Granier Guillaume , Ruffion Alain 
Published: December 2013

BACKGROUNDTaking into consideration the known overexpression of p16INK4a in histologically demonstrated high‐grade urothelial malignancies, the objective of the current study was to examine the value of p16INK4a overexpression and of p16/Ki‐67 dual labeling versus urinary cytology in the detection of urothelial lesions.METHODSImmunolabeling was performed on demounted and destained Papanicolaou slides after liquid‐based ThinPrep processing. Actual diagnoses were ascertained by cystoscopy controls and histopathology. Negative cases, papillary urothelial neoplasia of low malignant potential/low‐grade tumor, and high‐grade lesions were considered separately.RESULTSA total of 216 urine samples were collected from new patients with symptoms who were referred for cystoscopy (92 cases) or patients who were being followed after conservative treatment for lesions involving the bladder (117 cases) or the upper urinary tract (7 cases). p16INK4a positivity was assessed in 171 of the 216 cases (79.2%) and in 93 of 99 high‐grade cases with positive cytology (93.9%). Coexpression of p16/Ki‐67 in the same cells was observed in 119 of 216 cases (55.1%) and was noted in 18 of 51 cases of negative or papillary urothelial neoplasia of low malignant potential/low‐grade tumor (35.3%) and in 80 of 101 high‐grade tumors (79.2%) (P < .0001). Thirteen of 14 high‐grade intraurothelial lesions (92.8%) were dual labeled. When high‐grade tumors, disease progression (increased grade, muscle infiltration, and extension into the upper urinary tract), and cancer‐related death were grouped together as an endpoint, dual labeling demonstrated a sensitivity that was slightly higher than that of urinary cytology (82.5% vs 80.8%; P = .8), with 94.9% overall specificity.CONCLUSIONSWhen applied to the search for high‐grade and aggressive disease, p16/Ki‐67 dual labeling and urinary cytology appear to demonstrate comparable performance. Cancer (Cancer Cytopathol) 2014;122:211–220. © 2013 American Cancer Society.
Approximating Rough Stochastic PDEs
Authors: Hairer Martin , Maas Jan , Weber Hendrik 
Published: December 2013

We study approximations to a class of vector‐valued equations of Burgers type driven by a multiplicative space‐time white noise. A solution theory for this class of equations has been developed recently in Probability Theory Related Fields by Hairer and Weber. The key idea was to use the theory of controlled rough paths to give definitions of weak/mild solutions and to set up a Picard iteration argument.In this article the limiting behavior of a rather large class of (spatial) approximations to these equations is studied. These approximations are shown to converge and convergence rates are given, but the limit may depend on the particular choice of approximation. This effect is a spatial analogue to the Itô‐Stratonovich correction in the theory of stochastic ordinary differential equations, where it is well known that different approximation schemes may converge to different solutions.© 2014 Wiley Periodicals, Inc.
Increasing the Brightness of Cyanine Fluorophores for Single‐Molecule and Superresolution Imaging
Authors: Klehs Kathrin , Spahn Christoph , Endesfelder Ulrike , Lee Steven F. , Fürstenberg Alexandre , Heilemann Mike 
Published: December 2013

AbstractIn spite of their relatively low fluorescence quantum yield, cyanine dyes such as Cy3, Cy5, or Cy7 are widely used in single‐molecule fluorescence applications due to their high extinction coefficients and excellent photon yields. We show that the fluorescence quantum yield and lifetime of red‐emitting cyanine dyes can be substantially increased in heavy water (D2O) compared with water (H2O). We find that the magnitude of the quantum yield increase in D2O scales with the emission wavelength, reaching a particularly high value of 2.6‐fold for the most red‐emitting dye investigated, Cy7. We further demonstrate a higher photon yield in single‐molecule superresolution experiments in D2O compared to H2O, which leads to an improved localization precision and hence better spatial resolution. This finding is especially beneficial for biological applications of fluorescence microscopy, which are typically carried out in aqueous media and which greatly profit from the red spectral range due to reduced cellular auto‐fluorescence.
Smartphones in ecology and evolution: a guide for the app‐rehensive
Authors: Teacher Amber G. F. , Griffiths David J. , Hodgson David J. , Inger Richard 
Published: December 2013

AbstractSmartphones and their apps (application software) are now used by millions of people worldwide and represent a powerful combination of sensors, information transfer, and computing power that deserves better exploitation by ecological and evolutionary researchers. We outline the development process for research apps, provide contrasting case studies for two new research apps, and scan the research horizon to suggest how apps can contribute to the rapid collection, interpretation, and dissemination of data in ecology and evolutionary biology. We emphasize that the usefulness of an app relies heavily on the development process, recommend that app developers are engaged with the process at the earliest possible stage, and commend efforts to create open‐source software scaffolds on which customized apps can be built by nonexperts. We conclude that smartphones and their apps could replace many traditional handheld sensors, calculators, and data storage devices in ecological and evolutionary research. We identify their potential use in the high‐throughput collection, analysis, and storage of complex ecological information.
Crystal and Magnetic Structure of Sr2MIrO6 (M = Ca, Mg) Double Perovskites – A Neutron Diffraction Study
Authors: Kayser Paula , Martínez‐Lope María Jesús , Alonso Jose Antonio , Retuerto María , Croft Mark , Ignatov Alexander , Fernández‐Díaz Maria Teresa 
Published: December 2013

AbstractSr2CaIrO6 and Sr2MgIrO6 double perovskites have been prepared as polycrystalline powders from citrate precursors treated under oxygen pressure conditions. These compounds have been studied by X‐ray and neutron powder diffraction (NPD), magnetic measurements, and X‐ray absorption spectroscopy. The crystal symmetry of both oxides is monoclinic (space group P21/n), and the unit‐cell parameters are related to the ideal simple perovskite cell as a ≈ √2a0, b ≈ √2a0, c ≈ 2a0, β ≈ 90°, where a0 is the edge of the simple cubic ABO3 perovskite. This superstructure is a result of the 1:1 ordering of Ca/Mg and Ir ions over the B site and the distortion of the oxygen sublattice, which leads to a tilted three‐dimensional network of corner‐sharing BO6 octahedra. Magnetic measurements indicate an antiferromagnetic ordering below TN = 58 K for Sr2CaIrO6 and 74 K for Sr2MgIrO6. The low‐temperature magnetic structure of Sr2CaIrO6 was determined by NPD and selected from the possible magnetic solutions compatible with the P21/n space group according to the group‐theory representation. The propagation vector is k = (1/2 1/2 0). A canted antiferromagnetic structure is observed below TN with an ordered magnetic moment of 1.33(2) μB for the Ir6+ cations. Sr2MgIrO6 does not present magnetic reflections. An X‐ray absorption spectroscopy investigation gives an insight into the Ir oxidation states and suggests a hexavalent state for the Ca compound and an admixture of Ir6+ and Ir5+ for the Mg perovskite, in agreement with the NPD data, which indicate a significant oxygen understoichiometry for this material.
Linkage and Geometrical Isomers of Dichloridobis(triphenylphosphine)ruthenium(II) Complexes with Quinoline‐2‐carbaldehyde (Pyridine‐2‐carbonyl)hydrazone: Their Molecular Structures and Electrochemical and Spectroscopic Properties
Authors: Mori Asami , Suzuki Takayoshi , Sunatsuki Yukinari , Kobayashi Atsushi , Kato Masako , Kojima Masaaki , Nakajima Kiyohiko 
Published: December 2013

AbstractThe reactions of quinoline‐2‐carbaldehyde (pyridine‐2‐carbonyl)hydrazone (HL) and [RuCl2(PPh3)3] in various solvents at different temperatures gave the three geometrical isomers trans(Cl,Cl)‐, cis(Cl,Cl),trans(P,N)‐, and trans(P,P)‐[RuCl2(PPh3)2{HL‐κO(amide),κN(imine)}] (1, 2, and 3, respectively) as well as a linkage isomer trans(P,P)‐[RuCl2(PPh3)2{HL‐κN(imine),κN(quin)}] (4). The molecular and crystal structures of 1–4, together with both E and Z configurational isomers (with respect to the C=N double bond) of the free ligand HL, were determined by X‐ray analysis. The ligand HL adopted a Z form and acted as a κO(amide),κN(imine) bidentate ligand in 1–3, whereas it was an E isomer with a κN(imine),κN(quin) coordination mode in 4. The gradual thermal conversions of 1 to 2 and of 2 to 3 were observed in dichloromethane and ethanol, respectively, but an interconversion between 3 and 4 was not detected. In dichloromethane, all complexes have a reversible RuIII/II redox couple in the range 110–412 mV (vs. Ag/Ag+), and the redox potential was largely dependent on the coordination mode of HL and on the mutual configuration of the two PPh3 ligands. Such a potential shift can be interpreted as a combination of Cl–/amide O π‐donor and PPh3/quinoline N π‐acceptor orbital contributions to the RuII dπ orbitals [highest occupied molecular orbitals (HOMOs)]. Complexes 3 and 4 in acetonitrile showed a gradual spectral change, probably because of the substitution of the Cl– ligand by the acetonitrile solvent. In addition, 2–4 showed solvatochromic behavior even in noncoordinating solvents that resulted from a blueshift of the metal‐to‐ligand charge‐transfer (MLCT) transition band in polar solvents. These electrochemical and spectroscopic properties are also supported by DFT and time‐dependent DFT (TD‐DFT) calculations.
Syntheses and Applications of (Thio)Urea‐Containing Chiral Quaternary Ammonium Salt Catalysts
Authors: Novacek Johanna , Waser Mario 
Published: December 2013

AbstractWe herein report our efforts to obtain a new class of systematically modified bifunctional (thio)urea‐containing quaternary ammonium salts based on easily obtainable chiral backbones. Among the different classes of catalysts that were successfully synthesized, those based on trans‐1,2‐cyclohexane diamine were found to be the most powerful for the asymmetric α‐fluorination of β‐keto esters. Selectivities up to 93:7 could be obtained by using only 2 mol‐% of the optimized catalyst. The importance of the bifunctional nature of these catalysts was demonstrated by control experiments using simplified monofunctional catalyst analogues, which gave almost racemic product only.
Balancing Fluctuating Renewable Energy Generation Using Cogeneration and Heat Pump Systems
Authors: Mueller Stine , Tuth Richard , Fischer David , Wille‐Haussmann Bernhard , Wittwer Christof 
Published: December 2013

AbstractFuture energy supply will depend increasingly on fluctuating renewable energy generation. This requires new techniques and methods to deal with fluctuations in the grid. Thermal energy systems with thermal storage capacities linked to the electrical grid, for example, combined heat and power (CHP) and heat pump systems can provide additional and necessary storage capacities. This study examines the potential of CHP electricity generation and heat pump electricity consumption in residential buildings to balance fluctuations of renewable energy generation in Germany’s future energy system. The optimal operation strategy is derived using mixed integer linear programming. The results show that CHP and heat pump systems can shift electrical energy to balance the residual load. The positive and negative peak load are reduced by 14 % and 33 %, respectively, and the surplus energy generation decreases by 59 %. An increase in thermal storage capacity reinforces these effects.
Numerical investigation of the effects of dwell time duration in a two‐stage injection scheme on exergy terms in an IDI diesel engine by three‐dimensional modeling
Authors: Jafarmadar Samad , Zehni Alborz 
Published: December 2013

AbstractDwell duration of multiple‐injection scheme is an important parameter, which makes it possible to shift the tradeoff curve between soot and NOx closer to the origin. In this investigation, therefore, energy and exergy analyses are carried out for various two‐step injection schemes in which 25% of the total fuel is injected during the second pulse and the dwell time is increased from 5°CA (crank angle) to 30°CA by 5°CA increments. The calculations are performed for a Lister 8.1 indirect injection (IDI) diesel engine at full load operation. The energy analysis for these schemes is performed during a closed cycle by using a three‐dimensional CFD code. The cylinder pressure results for the baseline engine are compared with the corresponding experimental data and they show good agreement. For the exergy analysis, an in‐house computational code has been developed, which uses the results of energy analysis in various cases. With crank angle positions and dwell durations set for different injection schemes, various rates of exergy are calculated and the cumulative exergy components are identified separately. The results show that the values of work exergy and exergy efficiency decrease when the dwell duration is changed from 5°CA to 30°CA. Also, there is a sharp change in the exergy parameters when the dwell time reaches 25°CA.