bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Posteriori Error Estimates of a Combined Mixed Finite Element and Discontinuous Galerkin Method for a Kind of Compressible Miscible Displacement Problems
Authors: Yang Jiming , Xiong Zhiguang 
Published: January 2013

AbstractA kind of compressible miscible displacement problems which include molecular diffusion and dispersion in porous media are investigated. The mixed finite element method is applied to the flow equation, and the transport one is solved by the symmetric interior penalty discontinuous Galerkin method. Based on a duality argument, employing projection estimates and approximation properties, a posteriori residual-type hp error estimates for the coupled system are presented, which is often used for guiding adaptivity. Comparing with the error analysis carried out by Yang (Int. J. Numer. Meth. Fluids, 65(7) (2011), pp. 781–797), the current work is more complicated and challenging.
Nouvelles perspectives sur la mixité conjugale : le sujet et l’acteur au coeur de l’analyse
Authors: Therrien Catherine , Le Gall Josiane 
Published: January 2013

En prenant la teinte des préoccupations sociopolitiques et intellectuelles d’une période donnée, les travaux en sciences sociales reflètent « l’air du temps » (Varro, ce numéro). La façon dont les chercheurs appréhendent leurs objets d’étude est donc liée au temps, mais également à l’espace, c’est-à-dire au contexte dans lequel ils sont ancrés. Il nous a donc semblé intéressant de faire un survol des différentes perspectives théoriques ayant structuré le champ des études sur la mixité conjugale en débutant par une synthèse des cadres théoriques qui ont longtemps dominé les recherches sur les couples mixtes pour ensuite mettre au jour l’émergence de perspectives récentes qui accordent une place privilégiée aux acteurs et placent l’identité personnelle au coeur de leur analyse. Ces perspectives, qui ouvrent sur des thèmes et des points de vue nouveaux tout en contribuant à la transformation du langage même qui structure ce domaine de recherche, reflètent incontestablement les préoccupations de notre époque.
Les « couples mixtes » à travers le temps : vers une épistémologie de la mixité
Authors: Varro Gabrielle 
Published: January 2013

Lorsque l’on traite de mixité conjugale, la recherche exige de remettre dans leur contexte historique et politique les notions qui semblent les plus « évidentes », tels que les groupes d’origine et les identités… Après une évocation des racines de l’implication personnelle de l’auteure dans cette recherche – initialement orientée sur les rapports sociaux de sexe – la construction du sens des termes mixte et mixité en lien avec le genre, la religion et la nationalité est explorée dans une perspective historique. L’article se termine par un survol de quelques recherches françaises sur le couple mixte et les changements intervenus depuis les années 1950.
Subjective Cognitive Decline Plus and Longitudinal Assessment and Risk for Cognitive Impairment
Authors: Kang Moonil , Li Clara , Mahajan Arnav , Spat-Lemus Jessica , Durape Shruti , Chen Jiachen , Gurnani Ashita S. , Devine Sherral , Auerbach Sanford H. , Ang Ting Fang Alvin , Sherva Richard , Qiu Wei Qiao , Lunetta Kathryn L. , Au Rhoda , Farrer Lindsay A. , Mez Jesse 
Published: July 2024

ImportanceSubjective cognitive decline (SCD) is recognized to be in the Alzheimer disease (AD) cognitive continuum. The SCD Initiative International Working Group recently proposed SCD-plus (SCD+) features that increase risk for future objective cognitive decline but that have not been assessed in a large community-based setting.ObjectiveTo assess SCD risk for mild cognitive impairment (MCI), AD, and all-cause dementia, using SCD+ criteria among cognitively normal adults.Design, Setting, and ParticipantsThe Framingham Heart Study, a community-based prospective cohort study, assessed SCD between 2005 and 2019, with up to 12 years of follow-up. Participants 60 years and older with normal cognition at analytic baseline were included. Cox proportional hazards (CPH) models were adjusted for baseline age, sex, education, APOE ε4 status, and tertiles of AD polygenic risk score (PRS), excluding the APOE region. Data were analyzed from May 2021 to November 2023.ExposureSCD was assessed longitudinally using a single question and considered present if endorsed at the last cognitively normal visit. It was treated as a time-varying variable, beginning at the first of consecutive, cognitively normal visits, including the last, at which it was endorsed.Main Outcomes and MeasuresConsensus-diagnosed MCI, AD, and all-cause dementia.ResultsThis study included 3585 participants (mean [SD] baseline age, 68.0 [7.7] years; 1975 female [55.1%]). A total of 1596 participants (44.5%) had SCD, and 770 (21.5%) were carriers of APOE ε4. APOE ε4 and tertiles of AD PRS status did not significantly differ between the SCD and non-SCD groups. MCI, AD, and all-cause dementia were diagnosed in 236 participants (6.6%), 73 participants (2.0%), and 89 participants (2.5%), respectively, during follow-up. On average, SCD preceded MCI by 4.4 years, AD by 6.8 years, and all-cause dementia by 6.9 years. SCD was significantly associated with survival time to MCI (hazard ratio [HR], 1.57; 95% CI, 1.22-2.03; P &amp;lt;.001), AD (HR, 2.98; 95% CI, 1.89-4.70; P &amp;lt;.001), and all-cause dementia (HR, 2.14; 95% CI, 1.44-3.18; P &amp;lt;.001). After adjustment for APOE and AD PRS, the hazards of SCD were largely unchanged.Conclusions and RelevanceResults of this cohort study suggest that in a community setting, SCD reflecting SCD+ features was associated with an increased risk of future MCI, AD, and all-cause dementia with similar hazards estimated in clinic-based settings. SCD may be an independent risk factor for AD and other dementias beyond the risk incurred by APOE ε4 and AD PRS.
Terahertz Radiation Detectors Using CMOS Compatible SOI Substrates
Authors: Hasan Md Soyaeb , Khan Asif Abdullah , Shahzadi Shamaila , Bagheri Majid Haji , Ban Dayan 
Published: July 2024

AbstractIn recent years, silicon‐based room temperature Terahertz (THz) detectors have become the most optimistic research area because of their high speed, low cost, and unimpeded compatibility with mainstream complementary metal‐oxide‐semiconductor (CMOS) device technologies. However, Silicon (Si) suffers from low responsivity and high noise at THz frequencies. In this review, the recent advances in Si‐based THz detectors using silicon‐on‐insulator (SOI) substrates are presented. These offer several advantages over bulk counterparts, such as reduced parasitic capacitance, enhanced electric field confinement, and improved thermal isolation. The different types of THz detectors exploiting SOI substrate, such as conventional metal‐oxide‐semiconductor field effect transistors (MOSFETs), junction‐less MOSFETs, junction‐less nanowires field effect transistors (JLNWFETs), micro‐electromechanical system (MEMS), metal‐semiconductor‐metal (MSM) structures, and single electron transistor (SET), are discussed, and their key performances in terms of responsivity, noise equivalent power (NEP), bandwidth, and dynamic range are compared. The challenges and opportunities for further improvement of SOI THz detectors, such as device scaling, integration, and modulation, are also highlighted. This review may offer compelling evidence supporting the idea that SOI THz detectors have the potential to facilitate high performance, low power consumption, and scalability—qualities essential for advancing next‐level technologies.
Ultralong Lifespan Zero‐Cobalt/Nickel Prussian Blue Analogs Cathode Realized by Solid Solution Reaction Sodium Storage Mechanism
Authors: Wang Yichao , Jiang Ning , Liu Jiahe , Sun Shouyu , Wang Xinyu , Yang Jianhua , Yang Cheng , Liu Yu 
Published: July 2024

AbstractDespite their low cost and high specific capacity, the practical use of monoclinic Mn‐based Prussian blue analogs (Mn‐PBAs) is limited by poor cycling stability, primarily due to the structural degradation caused by the multiple phase transitions and Jahn–Teller effect associated with Mn3+ ions throughout the entire cycle. Herein, by synergistic incorporation of low‐cost Cu and Fe into the manganese sites of Mn‐PBAs, the ternary PBAs (T‐PBAs) achieve solid solution reaction of Na+ extraction and insertion, successfully eliminating the inherent multi‐phase transition from the sodium storage mechanism of T‐PBAs. Ex situ analysis and density functional theory calculations are employed to confirm that T‐PBAs consistently maintain a cubic phase with smaller lattice distortion rather than occur in conventional three‐phase transition during the charging and discharging processes, forcefully inhibiting the structural degradation of T‐PBAs. Therefore, the T‐PBAs showcase unprecedented cycling stability at both room temperature (10 000 cycles at 1 A g−1) and −20 °C (over 3000 h, 4200 cycles at 0.2 A g−1 without distinct capacity degradation), More importantly, when paired with commercial hard carbon, the T‐PBAs based sodium‐ion batteries exhibit excellent capacity retention (2000 cycles 76.8%), showcasing their immense potential in practical applications.
Chiral Self‐Discrimination Induced Luminescence Vapochromism of Binaphthol Imides for Anti‐Counterfeiting and Data Encryption
Authors: Zhang Yang , Chen Hong‐Ming , Lin Mei‐Jin 
Published: July 2024

AbstractChiral self‐discrimination plays a critical role in supramolecular chemistry and materials science. However, an ideal strategy for achieving chiral self‐discrimination remains elusive due to the inevitable nonspecific binding of incorrect enantiomers, and insufficient intrinsic optical activity of chiral molecules. Herein, a novel 1,1′‐binaphthol (BINOL) derivative with an imide group fused at the peri‐position of one naphthol scaffold is developed, which combines the dual functionalities of aggregation‐induced emission characteristic of BINOLs, and high emission of 1,8‐naphthalimides. The multiple molecular recognition between two hydroxyl groups in BINOL units and two carbonyl groups in 1,8‐naphthalimide moieties endows the precise chiral self‐discrimination behaviors. As expected, the homochiral aggregates exhibit reversible phase transitions, switching from non‐emission to bright green emission upon absorption and desorption of methanol vapor. In contrast, the heterochiral conglomerates exhibit irreversible yellow emission changes due to the impact of chiral self‐discrimination. Such chiral self‐discrimination‐induced luminescence vapochromism can be further applied to high‐level anti‐counterfeiting and data encryption. This work provides a new perspective on smart chiral organic materials based on chiral self‐discrimination.
Base‐Catalyzed Domino Isomerization/Oxidant‐Free Dehydrogenative Annulation of Allylic Alcohols: Scope, Mechanism, and Application
Authors: Zhou Xiongyang , Li Xun , Le Cheng , Li Jia‐Qi 
Published: July 2024

AbstractA domino reaction comprising four consecutive steps based on the strategy of isomerization of allylic alcohols was developed. This base‐catalyzed protocol provided an approach for constructing polysubstituted quinolines without additional additives. A wide range of di‐ or trisubstituted γ‐aminoaryl allylic alcohols bearing alkyl or (hetero)aryl substituents were transformed to a range of structurally diverse quinolines. The utility of this transformation was demonstrated by the application in the concise synthesis of several polysubstituted quinoline derivatives, including natural products and pharmacological agents. Preliminary mechanistic experiments suggest that the isomerization of γ‐aminoaryl allylic alcohol proceeds via an intramolecular 1,3‐hydrogen shift whereas for the aromatization of the dihydroquinoline intermediate two possible pathways exist: acceptorless dehydrogenation and transfer hydrogenation.
Manganese Catalyzed Site‐Selective Hydroxymethylation to 2‐Pyridones and Isoquinolones via C−H Activation
Authors: Rastogi Anushka , Kumar Mohit , Kumar Gangwar Manoj , Koley Dipankar 
Published: July 2024

AbstractPyridine‐directed regioselective C−H hydroxymethylation to pyridones and isoquinolones using para‐formaldehyde has been developed under manganese catalysis, offering a wide variety of hydroxymethylated products in 40–85% yields. This operationally simple methodology proceeds in one step using an earth‐ abundant first‐row transition metal‐catalyst without the generation of unwanted salt wastes. A mechanistic study revealed that the C−H metalation step is reversible but not the rate‐determining step. The introduction of hydroxymethyl group in the biologically relevant scaffolds could be used as an intermediate for valuable synthetic transformations.
Revolutionary Point‐of‐Care Wearable Diagnostics for Early Disease Detection and Biomarker Discovery through Intelligent Technologies
Authors: Haghayegh Fatemeh , Norouziazad Alireza , Haghani Elnaz , Feygin Ariel Avraham , Rahimi Reza Hamed , Ghavamabadi Hamidreza Akbari , Sadighbayan Deniz , Madhoun Faress , Papagelis Manos , Felfeli Tina , Salahandish Razieh 
Published: July 2024

AbstractEarly‐stage disease detection, particularly in Point‐Of‐Care (POC) wearable formats, assumes pivotal role in advancing healthcare services and precision‐medicine. Public benefits of early detection extend beyond cost‐effectively promoting healthcare outcomes, to also include reducing the risk of comorbid diseases. Technological advancements enabling POC biomarker recognition empower discovery of new markers for various health conditions. Integration of POC wearables for biomarker detection with intelligent frameworks represents ground‐breaking innovations enabling automation of operations, conducting advanced large‐scale data analysis, generating predictive models, and facilitating remote and guided clinical decision‐making. These advancements substantially alleviate socioeconomic burdens, creating a paradigm shift in diagnostics, and revolutionizing medical assessments and technology development. This review explores critical topics and recent progress in development of 1) POC systems and wearable solutions for early disease detection and physiological monitoring, as well as 2) discussing current trends in adoption of smart technologies within clinical settings and in developing biological assays, and ultimately 3) exploring utilities of POC systems and smart platforms for biomarker discovery. Additionally, the review explores technology translation from research labs to broader applications. It also addresses associated risks, biases, and challenges of widespread Artificial Intelligence (AI) integration in diagnostics systems, while systematically outlining potential prospects, current challenges, and opportunities.
Ureido‐Ionic Liquid Mediated Conductive Hydrogel: Superior Integrated Properties for Advanced Biosensing Applications
Authors: Ji Ruiying , Yan Shaopeng , Zhu Zhiyu , Wang Yaping , He Dan , Wang Kaikai , Zhou Daofeng , Jia Qike , Wang Xiuxiu , Zhang Botao , Shi Changcheng , Xu Ting , Wang Rong , Wang Rui , Zhou Yang 
Published: July 2024

AbstractIonic conductive hydrogels (ICHs) have recently gained prominence in biosensing, indicating their potential to redefine future biomedical applications. However, the integration of these hydrogels into sensor technologies and their long‐term efficacy in practical applications pose substantial challenges, including a synergy of features, such as mechanical adaptability, conductive sensitivity, self‐adhesion, self‐regeneration, and microbial resistance. To address these challenges, this study introduces a novel hydrogel system using an imidazolium salt with a ureido backbone (UL) as the primary monomer. Fabricated via a straightforward one‐pot copolymerization process that includes betaine sulfonate methacrylate (SBMA) and acrylamide (AM), the hydrogel demonstrates multifunctional properties. The innovation of this hydrogel is attributed to its robust mechanical attributes, outstanding strain responsiveness, effective water retention, and advanced self‐regenerative and healing capabilities, which collectively lead to its superior performance in various applications. Moreover, this hydrogel exhibited broad‐spectrum antibacterial activity. Its potential for biomechanical monitoring, especially in tandem with contact and noncontact electrocardiogram (ECG) devices, represents a noteworthy advancement in precise real‐time cardiac monitoring in clinical environments. In addition, the conductive properties of the hydrogel make it an ideal substrate for electrophoretic patches aimed at treating infected wounds and consequently enhancing the healing process.
HSF5 Deficiency Causes Male Infertility Involving Spermatogenic Arrest at Meiotic Prophase I in Humans and Mice
Authors: Liu Mohan , Wang Lingbo , Li Yifei , Zhi Erlei , Shen Gan , Jiang Xiaohui , Li Dingming , Zhao Xinya , Ruan Tiechao , Jiang Chuan , Wang Xiang , Zhang Xueguang , Zheng Yanjiang , Wu Bangguo , Ou Ningjing , Zhao Guicheng , Dai Siyu , Zhou Ruixi , Yang Li , Yang Yihong , Liu Hanmin , Shen Ying 
Published: July 2024

AbstractMeiosis is a specialized cell division process that generates gametes for sexual reproduction. However, the factors and underlying mechanisms involving meiotic progression remain largely unknown, especially in humans. Here, it is first showed that HSF5 is associated with human spermatogenesis. Patients with a pathogenic variant of HSF5 are completely infertile. Testicular histologic findings in the patients reveal rare postmeiotic germ cells resulting from meiotic prophase I arrest. Hsf5 knockout (KO) mice confirms that the loss of HSF5 causes defects in meiotic recombination, crossover formation, sex chromosome synapsis, and sex chromosome inactivation (MSCI), which may contribute to spermatocyte arrest at the late pachytene stage. Importantly, spermatogenic arrest can be rescued by compensatory HSF5 adeno‐associated virus injection into KO mouse testes. Mechanistically, integrated analysis of RNA sequencing and chromatin immunoprecipitation sequencing data revealed that HSF5 predominantly binds to promoters of key genes involved in crossover formation (e.g., HFM1, MSH5 and MLH3), synapsis (e.g., SYCP1, SYCP2 and SYCE3), recombination (TEX15), and MSCI (MDC1) and further regulates their transcription during meiotic progression. Taken together, the study demonstrates that HSF5 modulates the transcriptome to ensure meiotic progression in humans and mice. These findings will aid in genetic diagnosis of and potential treatments for male infertility.
Chaotropic Ions Mediated Polymer Gelation for Thermal Management
Authors: Yin Chenxiao , Sun Jingrui , Cui Chang , Yang Ke‐Ke , Shi Ling‐Ying , Li Yiwen 
Published: July 2024

AbstractEnergy and environmental issues have increasingly garnered significant attention for sustainable development. Flexible and shape‐stable phase change materials display great potential in regulation of environmental temperature for energy saving and human comfort. Here, inspired by the water absorption behavior of salt‐tolerant animals and plants in salinity environment and the Hofmeister theory, highly stable phase change salogels (PCSGs) are fabricated through in situ polymerization of hydrophilic monomers in molten salt hydrates, which can serve multiple functions including thermal management patches, smart windows, and ice blocking coatings. The gelation principles of the polymer in high ion concentration solution are explored through the density functional theory simulation and verified the feasibility of four types of salt hydrates. The high concentration chaotropic ions strongly interacted with polymer chains and promoted the gelation at low polymer concentrations which derive highly‐stable and ultra‐moisturizing PCSGs with high latent heat (> 200 J g−1). The synergistic adhesion and transparency switching abilities accompanied with phase transition enable their smart thermal management. The study resolves the melting leakage and thermal cycling stability of salt hydrates, and open an avenue to fabricate flexible PCM of low cost, high latent heat, and long‐term durability for energy‐saving, ice‐blocking, and thermal management.
Highly Sensitive Room‐Temperature Detection of Ammonia in the Breath of Kidney Disease Patients Using Fe2Mo3O8/MoO2@MoS2 Nanocomposite Gas Sensor
Authors: Li Xian , Zeng Wang , Zhuo Shangjun , Qian Bangwei , Chen Qiao , Luo Qun , Qian Rong 
Published: July 2024

AbstractA novel Fe2Mo3O8/MoO2@MoS2 nanocomposite is synthesized for extremely sensitive detection of NH3 in the breath of kidney disease patients at room temperature. Compared to MoS2, α‐Fe2O3/MoS2, and MoO2@MoS2, it shows the optimal gas‐sensing performance by optimizing the formation of Fe2Mo3O8 at 900 °C. The annealed Fe2Mo3O8/MoO2@MoS2 nanocomposite (Fe2Mo3O8/MoO2@MoS2‐900 °C) sensor demonstrates a remarkably high selectivity of NH3 with a response of 875% to 30 ppm NH3 and an ultralow detection limit of 3.7 ppb. This sensor demonstrates excellent linearity, repeatability, and long‐term stability. Furthermore, it effectively differentiates between patients at varying stages of kidney disease through quantitative NH3 measurements. The sensing mechanism is elucidated through the analysis of alterations in X‐ray photoelectron spectroscopy (XPS) signals, which is supported by density functional theory (DFT) calculations illustrating the NH3 adsorption and oxidation pathways and their effects on charge transfer, resulting in the conductivity change as the sensing signal. The excellent performance is mainly attributed to the heterojunction among MoS2, MoO2, and Fe2Mo3O8 and the exceptional adsorption and catalytic activity of Fe2Mo3O8/MoO2@MoS2‐900 °C for NH3. This research presents a promising new material optimized for detecting NH3 in exhaled breath and a new strategy for the early diagnosis and management of kidney disease.
Nitrogen‐fixing bacteria boost floral attractiveness in a tropical legume species during nutrient limitation
Authors: Souza Caroline , Valadão‐Mendes Lorena B. , Schulze‐Albuquerque Isadora , Bergamo Pedro J. , Souza Douglas D. , Nogueira Anselmo 
Published: July 2024

AbstractPremiseLegumes establish mutualistic interactions with pollinators and nitrogen (N)‐fixing bacteria that are critical for plant reproduction and ecosystem functioning. However, we know little about how N‐fixing bacteria and soil nutrient availability affect plant attractiveness to pollinators.MethodsIn a two‐factorial greenhouse experiment to assess the impact of N‐fixing bacteria and soil types on floral traits and attractiveness to pollinators in Chamaecrista latistipula (Fabaceae), plants were inoculated with N‐fixing bacteria (NF+) or not (NF‐) and grown in N‐rich organic soil (+N organic soil) or N‐poor sand soil (‐N sand soil). We counted buds and flowers and measured plant size during the experiment. We also measured leaf, petal, and anther reflectance with a spectrophotometer and analyzed reflectance curves. Using the bee hexagon model, we estimated chromatic contrasts, a crucial visual cues for attracting bees that are nearby and more distant.ResultsNF+ plants in ‐N sand soil had a high floral display and color contrasts. On the other hand, NF‐ plants and/or plants in +N organic soil had severely reduced floral display and color contrasts, decreasing floral attractiveness to bee pollinators.ConclusionsOur findings indicate that the N‐fixing bacteria positively impact pollination, particularly when nutrients are limited. This study provides insights into the dynamics of plant–pollinator interactions and underscores the significant influence of root symbionts on key floral traits within tropical ecosystems. These results contribute to understanding the mechanisms governing mutualisms and their consequences for plant fitness and ecological dynamics.