bluuebunny/crossref_metadata_2025_split huggingface dataset:
Premedication and general anesthetic agents decrease plasma concentration of the endocannabinoid anandamide in dogs
Authors: Chua Andrew , McMichael Maureen A. , Jukier Tom , Arnold Robert D. , Hung Wan-Chu Ellan , Harris Stephanie , Zhang Chu , Bustamante Hedie Almagro 
Published: February 2025

Abstract

Objective
To determine the effect of premedication followed by isoflurane (ISO) versus sevoflurane (SEVO), length of general anesthesia (GA), and the amount of IV fluid administered on plasma endocannabinoid arachidonoyl ethanolamide (anandamide; AEA) concentrations in dogs undergoing GA.

Methods
This study was an analysis of samples collected during a previously designed prospective, randomized, single-blinded experimental study involving 21 client-owned dogs undergoing GA. Samples were collected from March through October 2021. Dogs were randomized to ISO or SEVO as the inhalant anesthetic. Blood samples collected before and after GA were used to measure plasma AEA concentrations using HPLC-MS-MS. Data included signalment, length of GA (minutes), surgery performed, fluid volume administered (milliliters per kilogram), and treatment with NSAIDs or steroids. Statistical analyses included power analysis, normality testing, and adjusted linear mixed models.

Results
Plasma AEA concentrations significantly decreased after GA in both groups. Least squares mean AEA concentration decreased from 29 to 12.3 ng/mL in the ISO group and from 26.6 to 11.1 ng/mL in the SEVO group. There were no significant differences between groups or associations with anesthesia duration, fluid volume, surgery, or NSAID/steroid use.

Conclusions
Plasma AEA concentrations were significantly reduced after GA in both the ISO and SEVO groups. This reduction may be influenced by other anesthesia agents, such as dexmedetomidine, hydromorphone, and propofol.

Clinical Relevance
This study is the first to highlight a potential interaction between premedication, GA, and endocannabinoid signaling. Further research is needed to explore these findings and their implications for pain management and neuroprotection.
Pulsed field ablation in medicine: irreversible electroporation and electropermeabilization theory and applications
Authors: Jacobs Edward J , Rubinsky Boris , Davalos Rafael V 
Published: February 2025

Abstract

Background
Focal ablation techniques are integral in the surgical intervention of diseased tissue, where it is necessary to minimize damage to the surrounding parenchyma and critical structures. Irreversible electroporation (IRE) and high-frequency IRE (H-FIRE), colloquially called pulsed-field ablation (PFA), utilize high-amplitude, low-energy pulsed electric fields (PEFs) to nonthermally ablate soft tissue. PEFs induce cell death through permeabilization of the cellular membrane, leading to loss of homeostasis. The unique nonthermal nature of PFA allows for selective cell death while minimally affecting surrounding proteinaceous structures, permitting treatment near sensitive anatomy where thermal ablation or surgical resection is contraindicated. Further, PFA is being used to treat tissue when tumor margins are not expected after surgical resection, termed margin accentuation. This review explores both the theoretical foundations of PFA, detailing how PEFs induce cell membrane destabilization and selective tissue ablation, the outcomes following treatment, and its clinical implications across oncology and cardiology.

Conclusions
Clinical experience is still progressing, but reports have demonstrated that PFA reduces complications often seen with thermal ablation techniques. Mounting oncology data also support that PFA produces a robust immune response that may prevent local recurrences and attenuate metastatic disease. Despite promising outcomes, challenges such as optimizing field delivery and addressing variations in tissue response require further investigation. Future directions include refining PFA protocols and expanding its application to other therapeutic areas like benign tissue hyperplasia and chronic bronchitis.
Penerapan Object Detection Menggunakan Deep Learning Yolov8 Untuk Mengidentifikasi Sampah Anorganik (Maksimal Sepuluh Objek) Dalam Satu Citra
Authors: Visen  , Charibaldi Novrido 
Published: February 2025

Masalah sampah di Indonesia masih menjadi momok yang belum teratasi, terutama karena tingginya pertumbuhan penduduk. Sampah anorganik menjadi perhatian utama karena sulit terurai dan mencemari lingkungan untuk waktu yang lama. Oleh karena itu, diperlukan sistem pendeteksi otomatis berbagai jenis sampah anorganik dalam berbagai kondisi, guna mengurangi dampak pencemaran dan memfasilitasi proses daur ulang yang lebih efisien. Penelitian ini menggunakan kecerdasan buatan (deep learning) dengan model YOLOv8 nano untuk mengenali beberapa jenis sampah anorganik. Data yang dipakai berasal dari kamera gawai dan gabungan dataset Kaggle, totalnya ada 2459 data untuk lima jenis sampah. Pembagian datanya 1967 untuk pelatihan, 246 untuk validasi, dan 246 untuk pengujian. Pengujian dilakukan pada gambar yang berisi 1 hingga 12 objek sampah dalam kondisi yang berbeda-beda. Hasilnya menunjukkan akurasi model yang tinggi, dengan nilai mAP50 mencapai 87.1% dan mAP50-95 sebesar 72.1%. Nilai presisi mencapai 86.2% dan recall mencapai 79.1% pada iterasi ke-50, menunjukkan kinerja model yang baik. Model ini juga handal dalam mendeteksi hingga sepuluh objek sampah dalam satu gambar. Namun, kemampuan deteksi menurun ketika objek sampah melebihi sepuluh. Artinya, model masih bisa mengenali objek meski jumlahnya banyak, tetapi akurasi klasifikasinya menurun.

Abstract
The waste problem in Indonesia remains a persistent issue, especially due to the high population growth. Inorganic waste is a major concern because it is difficult to decompose and contaminates the environment for a long time. Therefore, an automatic detection system for various types of inorganic waste in different conditions is needed to reduce the impact of pollution and facilitate more efficient recycling processes. This study uses artificial intelligence (deep learning) with the YOLOv8 nano model to recognize several types of inorganic waste. The data used comes from mobile phone cameras and a combination of Kaggle datasets, totaling 2,459 data points for five types of waste. The data is divided into 1,967 for training, 246 for validation, and 246 for testing. The testing was conducted on images containing 1 to 12 waste objects in various conditions. The results show a high model accuracy, with an mAP50 value of 87.1% and mAP50-95 of 72.1%. The precision value reaches 86.2%, and the recall reaches 79.1% at the 50th iteration, indicating good model performance. This model is also reliable in detecting up to ten waste objects in a single image. However, the detection ability decreases when the number of waste objects exceeds ten. This means that the model can still recognize objects even when there are many, but its classification accuracy decreases.
Sistem Monitoring Budidaya Melon Melalui Greenhouse Berbasis Internet Of Things
Authors: Apriyani Meyti Eka , Ismail Ade , Widya Andini Amelia 
Published: February 2025

Pertanian melon merupakan usaha yang menjanjikan namun rentan terhadap perubahan cuaca dan tantangan pengelolaan, seperti kebutuhan air yang tinggi serta risiko serangan hama dan penyakit. Penggunaan greenhouse dapat membantu petani memanipulasi kondisi lingkungan guna mengurangi risiko penyakit yang disebabkan oleh perubahan cuaca. Penelitian ini bertujuan mengembangkan sistem pintar pada greenhouse untuk memantau dan mengontrol perawatan tanaman melon secara efektif dan efisien. Sistem ini memanfaatkan alat seperti pompa air dan lampu, yang dioperasikan berdasarkan data sensor yang diperbarui setiap 10 detik, dengan keputusan pengambilan tindakan dilakukan setiap 1 menit. Keputusan sistem tidak hanya bergantung pada data sensor, tetapi juga mempertimbangkan faktor waktu, karena tanaman tidak selalu membutuhkan penyiraman atau pencahayaan setiap saat. Sensor kelembapan tanah kapasitif ditempatkan pada polibag tanaman di tengah barisan untuk pemantauan yang akurat. Hasil pengujian menunjukkan bahwa sistem otomatis menghasilkan pertumbuhan dan berat buah melon yang lebih baik dibandingkan dengan sistem manual, dengan rata-rata berat melon 2,1 kg pada sistem otomatis, sementara pada sistem manual hanya 1,6 kg. Penerapan Smart Greenhouse ini terbukti mengurangi biaya perawatan dan meningkatkan produksi, menawarkan solusi efektif dalam pertanian modern.

Abstract
Melon farming is a promising business but is vulnerable to weather changes and management challenges, such as high water requirements and the risk of pests and diseases. The use of greenhouses can help farmers manipulate environmental conditions to reduce the risk of diseases caused by weather changes. This study aims to develop a smart system in a greenhouse to monitor and control melon plant care effectively and efficiently. This system utilizes tools such as water pumps and lights, which are operated based on sensor data that is updated every 10 seconds, with decisions to take action every 1 minute. System decisions do not only depend on sensor data, but also consider time factors, because plants do not always need watering or lighting at all times. Capacitive soil moisture sensors are placed on plant polybags in the middle of the rows for accurate monitoring. The test results showed that the automatic system produced better melon growth and fruit weight compared to the manual system, with an average melon weight of 2.1 kg in the automatic system, while in the manual system it was only 1.6 kg. The implementation of Smart Greenhouse has been proven to reduce maintenance costs and increase production, offering an effective solution in modern agriculture.
Hypersensitivity pneumonitis in a child (observational data for six years): A clinical case
Authors: Chulkov V. S. , Medvedeva L. V. , Minina E. E. , Fastakovskaya E. V. 
Published: February 2025

Background. Hypersensitivity pneumonitis refers to a rare interstitial lung disease that requires differential diagnosis with a large spectrum of nosologies. However, the prevalence of hypersensitivity pneumonitis in the population remains unclear, partly due to low awareness among healthcare professionals of various specialties regarding this condition, as well as diagnostic challenges. Many authors emphasize the necessity of a detailed analysis of professional and environmental factors affecting the patient as one of the crucial steps in diagnosing hypersensitivity pneumonitis. The prognosis for hypersensitivity pneumonitis in children is more favorable than in adults, with complete clinical and functional recovery possible in most cases if the causative antigen is eliminated.Case description. The paper presents data from a six-year observation of a 9-year-old girl. Within six months prior to her consultation, she developed respiratory complaints (shortness of breath, respiratory distress, fits of dry coughing), poor tolerance to physical exertion, and chronic weakness. She was monitored and treated for bronchial asthma by a pulmonologist without significant clinical improvement. Subsequently, specialists at a regional center conducted extensive work on differential diagnosis and verification of the disease through meticulous collection of anamnesis and clinical data and the use of modern laboratory and instrumental resources. Effective treatment was selected, and recommendations were given in order to correct influencing factors (change of residence and living conditions). A clear improvement in clinical, laboratory, and instrumental data was demonstrated over the observation period, with significant effects achieved within a year from the start of therapy. Improvements were noted in both volume and flow parameters on spirometry, with no restrictive disorders observed; the most indicative changes were revealed in the dynamics of high-resolution computed tomography.Conclusion. The presented clinical case demonstrates the necessity of paying special attention to thorough history-taking and identifying potential causal factors. A distinctive feature of the disease consists in reversible symptoms, sustained remission, and a favorable prognosis under conditions of timely diagnosis, treatment, and removal of the causal factor.
PERANCANGAN PERKERASAN JALAN KOMPOSIT PADA RUAS JALAN KANITI DESA PENFUI TIMUR KABUPATEN KUPANG
Authors: Lourdes Atrianus , Pedo Krisantus Satrio Wibowo , Bela Krisantos Ria 
Published: February 2025

Keadaan Infrastruktur Jalan pada Desa Penfui Timur kurang memadai pada beberapa segmen jalan, karena peningkatan jalan tidak sebanding dengan petumbuhan desa. Salah satu perencanaan perbaikan infrastruktur desa adalah Perbaikan pada ruas Jalan Kaniti (Jembatan Kaniti). Perencanaan perkerasan komposit jalan pada ruas ini perlu dilakukan sebagai salah satu alternatif dalam pemilihan tipe perkerasan yang tepat. Metode penelitian ini menggunakan metode perhitungan berdasarkan pedoman perencanaan tebal lapis perkerasan kaku Pd-T-14-2003 dan perhitungan tebal lapis perkerasan lentur metode analisa komponen. Hasil desain berupa Perkerasan Beton Semen Bersambung Dengan Tulangan (BBDT) umur rencana 20 tahun tanpa bahu beton dengan tebal pelat beton 22 cm, lebar pelat 5,5 m, panjang sambungan pelat 5 m, memiliki sambungan susut dan menggunakan ruji serta tulangan melintang dan memanjang beton. Tebal pelat 22 cm serta memenuhi syarat pada hasil analisa fatik dan erosi. Hasil perencanaan tebal lapis perkeraasan komposit dengan umur rencana 20 tahun adalah terdiri dari tanah dasar, pondasi bawah berupa agregat A setebal 10 cm, CBK (Campuran Beton Kurus) setebal 15 cm, lapis permukaan berupa pelat beton setebal 22 cm dan aspal tipe HRS (Hot Rolled Sheet) setebal 5 cm
Sexo pensante, sexo cambiante: la educación media y superior de las españolas en los años cincuenta
Authors: Morcillo Gómez Aurora 
Published: February 2025

La universidad franquista se regularía por la Ley de Odernación Universitaria de 1943, en vigor hasta 1970. En este artículo la autora sostiene que, lejos de excluir a las mujeres explicitamente de la educación superior, el régimen promueve un ideal de mujer católica o “true Catholic womanhood” intrínsecamente opuesto al sujeto universitario definido en la letra de la ley. La educación media que en los años cincuenta se regula mediante dos reformas legales, se diseña de tal modo que a las jóvenes se las desanimaba a estudiar o si lo hacian a elegir una carrera apropiada a su sexo. El artículo se centra en los años cincuenta, cuando el franquismo entra en la transición de la autarquía al consumismo y las relaciones de género se han de redefinir para amoldarse a las circunstancias.
Systematic Literature Review: Review of Erosion Control Methods in the 21st Century
Authors: EJIOFOR EZE ANTHONY 
Published: February 2025

Erosion control has become one of the foremost environmental issues of the 21st century due to the accelerated impacts of climate change, land degradation, and unsustainable land management. The method of Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) was used. Series of eligibility/exclusion criteria were applied: only journal articles, peer reviewed conference papers and government publications were selected; articles in English publications were chosen as well. Only papers published in 1994 Onwards were selected. This systematic review examines the broad array of erosion control methods developed and deployed in the past two decades and their efficacy, sustainability, and applicability across contexts. The review highlights the significance of vegetative strategies, such as cover crops, agroforestry, and reforestation, which not only reduce soil erosion but also enhance ecosystem services such as carbon sequestration and biodiversity conservation. Structural strategies, such as terracing, check dams, and geosynthetic materials, remain effective but are typically limited by their high expense and maintenance requirements. Bioengineering techniques, by vegetative and structural incorporation, are increasingly favored for the double advantage of immediate erosion control alongside promoting long-term ecological recovery. Conservation tillage and soil organic amendments are agricultural management practices that have demonstrated the significance of improved soil quality and tensile strength. Moreover, community and policy-level interventions, such as integrated watershed management and payment for ecosystem services, have also emerged as indispensable methods of combatting erosion at the landsscape level. Despite taking great leaps forward, scaling them up and sustainability over the long term continues to pose a problem. This review underlines integrating technical measures into community involvement coupled with policy action through locally determined strategies. Present studies must focus on optimizing the use of erosion control techniques, optimizing the involvement of stakeholders, and detailing innovative options for addressing emerging problems in a rapidly evolving world. It is feasible to minimize the impact of erosion and promote sustainable land use for generations to come by employing a multidisciplinary method.
Enhancing Scalability in Preventive Interventions: Theoretical Framework and Practical Applications for Expanding the Reach and Impact of Preventive Intervention Programs
Authors: Saberi Sahba 
Published: February 2025

Background: The field of preventive psychological intervention has made significant strides, but a need persists for comprehensive frameworks with a strategic direction for large-scale implementation. Existing preventive programs face limitations that hinder their ability to reach a larger audience and have a broad impact.Body: The Fount Prevention Framework aims to bridge this gap by proposing strategies to enable preventive intervention programs to achieve scalability, reach a wider audience, enhance mental health outcomes, reduce the financial burden, and allow faster access for communities. This paper examines the fundamental features of the Fount Prevention Framework, which serves as a protocol designed to guide prevention and mental health promotion programs in achieving a broader impact.Additionally, the paper examines a preventive program, Mind Wellbeing, developed based on this framework, as a practical application of how these principles can be implemented. Strategies that render the program independent of experts, trained facilitators, and technology-based delivery modes—including the use of a self-help, group-based mode of program delivery through physical, paperback workbooks—are examined. Other features of the program, such as its transdiagnostic, universal, and comprehensive nature, are explored in light of the need to foster widespread prevention coverage and broader public engagement and participation. Limitations and challenges of the program are also addressed, offering insights into the broader application of the framework and considerations necessary for achieving a goal of this magnitude.Conclusion: Through ongoing empirical research and innovative strategizing to overcome the intrinsic challenges faced by programs of this nature, the measures proposed by this framework may present a compelling avenue for influencing global mental health and a potential pathway to enhancing mental health outcomes worldwide.
The Day After: The Post-Crisis IASA and Daemons That Can Help
Authors: Jędrzejko Paweł 
Published: February 2025

Amid the chaos of pandemics or wars, the conflict extends beyond mere human struggles with (their) commonsensically understood “demons”—fears, ambitions, traumas, desires, angsts, and all of other conditions and structures always-already in place even before we become aware of them. Although, beyond doubt, such “side effects” of being-in-the-world or being-with-others generate facts that are effect-producing, whether these facts prove to be morally actionable depends on if and how we engage them. Summing up the mission of the post-Crisis IASA, I build my argument around Friedrich Nietzsche's concept of personal responsibility in the face of the Daemon of Eternal Recurrence, Paul Ricoeur’s phenomenological hermeneutics, and leading Western existentialists to demonstrate that, at least in the Western perspective, the conflict also entails, perhaps more crucially, a fierce battle between the daimōn and the daemonium. Recognizing the eternal recurrence of such catastrophes such as pandemics or wars, the “Greek mindset,” embracing the daimōn, fosters an existential philosophy that emphasizes participation in the realm of immanence, shaping our ethical considerations and propelling actions. In contrast, the “Latin approach,” in constant fear of the daemonium, seems to foster self-perception as constantly plunged in “fear and trembling,” despairingly “sick unto death,” and prone to attributing malevolent forces to the “evil spirits,” thereby generating configurations that shift the narrative towards self-absolution, and ultimately legitimize refigurations that, diluting personal responsibility, delegate it to transcendence. Embracing Greek thought, we engage in an ongoing quest with facta-ficta, revising language critically (Gr. κρίνω), without expecting finality in our categories, acknowledging that our imperfect language is essential for defining our existence within immanence. Conversely, “Latin thinking,” in which demons are seen as elements of a transcendent realm—unreachable without relinquishing the self, or as part of a faith-based narrative, and in which human is potentially lacking tangible impact—involves the risk of rendering us indifferent to historical lessons, legitimizing a fatalistic nihil novi as a self-fulfilling prophecy.
АҚЫМЕТ БАЙТҰРСЫНҰЛЫНЫҢ БАСТАУЫШ МЕКТЕПКЕ ҚАТЫСТЫ ҰСТАНЫМДАРЫ
Authors: Қапалбек Б.С. , Каленбекова А.Е. 
Published: February 2025

XXI ғасыр білім беру жүйесін жетілдіру ғасыры. Ақпарат көп және қолжетімді. Енді оны жүйелеп беру өзекті мәселелердің біріне айналып отыр. Мақалада бастауыштың білім жүйесінің маңыздылығы мен реттілігі қарастырылады. Қоғамның дамуының басты тұтқасы адам болса, сол адамның білімді болуы бастауыштан бастау алады. Бiлiм беру саласының негiзгi мiндетi – білімді тұлғаны шығармашылық әлеуеті қалыптасқан, жаңашыл бастамаларды жүзеге асыра алатын, өз іс әрекетін басқара алатын адамға айналдыру. Осы мәселе негізінде теориялық талдау әдістері, педагогикалық тәжірибені зерттеу әдістері, бағалау, пайымдау тәсілдері, дамыған елдердің тәжірибелерін талдау, салыстыру әдістері қолданылды. Аталған әдістемелік негіздемелердің кезеңінде: бастауыш білім жүйесін қалыптастыру, оқытылатын пәндерді негіздеу, оқу үдерісін жүзеге асыру қарастырылып, жүргізілген нәтиже барысында сипаттама беріледі.
Мақаланың мазмұнында қазақ қоғамындағы білім жүйесінің тарихы мен Ақымет Байтұрсынұлының бастауыш сыныпқа қатысты педагогикалық ұстанымдары талданады. Сондай-ақ, Қазақстанның білім жүйесі басқа да дамыған Жапония, Түркия, Оңтүстік Корея, Финляндия мемлекеттерінің бастауыш білім беру жүйелерімен салыстырмалы талданады. Ұлт ұстазы Ақымет Байтұрсынұлының бастауыш мектепке қатысты ұстанымдары, айтқан пікірлері, тұжырымдарының бүгінгі күні де өзекті, қолдануға жарамды екендігін ғылымның бүгінгі деңгейінен бағалап, лингвистикалық тұрғыдан негізделеді. Қазіргі бастауыш мектепте оқытылатын пәндер саны әлемдегі дамыған елдермен салыстырғанда солардың стандарттарына сәйкес келмейтіндігі дәлелденеді.
Мақаланың қорытынды бөлімінде дамыған мемлекеттердің мектептегі білім беру жүйелерінің артықшылықтары мен кемшіліктері ескеріліп, ұлт ұстазының бастауышқа қатысты ұстанымдары бүгінгі қолданыстағы жүйемен салыстырылып, артықшылықтары дәлелденеді.