bluuebunny/crossref_metadata_2025_split huggingface dataset:
Séparation et médiation familiale
Authors: Sehil Saïda , Duret-Salzer Florence 
Published: February 2013

Cet article propose de développer l’intérêt de la médiation familiale dans le cadre de la séparation conjugale, sachant que la médiation familiale peut aussi concerner tous les champs de la séparation dans la famille (entre membres d’une même fratrie, avec les grands parents, les jeunes adultes, ...). Il met en lumière les spécificités de la médiation familiale par rapport au travail thérapeutique. L’article expose le cadre déontologique de la médiation familiale ainsi que son articulation avec le judiciaire. Il est question aussi de présenter les grandes lignes méthodologiques de cette pratique ainsi que les différents sujets qui y sont abordés. Deux récits de situation viendront illustrer le développement. L’article expose comment la médiation familiale peut aider les personnes à ne plus être un couple conjugal pour devenir un « couple » parental, vis à vis de ce qui les unit à vie : leurs enfants.
Incidence of Retinal Hemorrhages in Abusive Head Trauma
Authors: Gaffar Majida A. , Esernio-Jenssen Debra , Kodsi Sylvia R. 
Published: February 2013

Purpose:
To evaluate whether a relationship exists between the presence of retinal hemorrhages and confessions and/or identified perpetrators in cases of abusive head trauma.

Methods:
A retrospective chart review was conducted of all abusive head trauma cases. All cases that met criteria for abusive head trauma were placed into one of three categories: perpetrator confessed (category A), perpetrator identified without confession (category B), and no perpetrator identified (category C).

Results:

Forty-eight cases met the criteria for abusive head trauma, with 18, 16, and 14 cases in categories A, B, and C, respectively. Retinal hemorrhages were identified in 16 of 18 (88%) cases in category A, 12 of 16 (75%) in category B, and 6 of 14 (43%) in category C. A statistically significant difference regarding the presence of retinal hemorrhages was seen for perpetrator identified (28 of 34 or 82%) compared to no perpetrator identified (6 of 14 or 43%) (
P
= .034). The difference in retinal hemorrhages was correlated to the higher incidence of acute presentation in the perpetrator identified group (31 of 34 or 91%) compared to that in the perpetrator not identified group (9 of 14 or 64%) (
P
= .023).

Conclusion:
The incidence of retinal hemorrhages in abusive head trauma for identified perpetrators, regardless of a confession, is similar. However, there is a statistically significant decrease in the incidence of retinal hemorrhages in abusive head trauma when comparing identified perpetrators to non-identified perpetrators. This decreased incidence of retinal hemorrhages was statistically correlated to a lower incidence of acute presentation in victims of abusive head trauma without an identified perpetrator.

[J Pediatr Ophthalmol Strabismus 2013;50(3):169–172.]
Two Techniques for Sutureless Intrascleral Posterior Chamber IOL Fixation
Authors: Totan Yuksel , Karadag Remzi 
Published: February 2013

PURPOSE:
To compare two different techniques for sutureless scleral fixation of posterior chamber intraocular lens (IOL) in patients with insufficient capsule support.

METHODS:
Of 29 patients, 17 received the needle technique using a 24-gauge needle for the scleral tunnel opening and 12 received the novel trocar technique, in which the scleral tunnel was prepared with a 25-gauge transconjunctival sutureless vitrectomy trocar and a three-piece foldable IOL was placed through clear corneal incision. Visual acuity, intraocular pressure, related complications, and IOL stability were assessed postoperatively.

RESULTS:

Postoperative visual acuities significantly improved with both techniques (
P
= .028 and .012, respectively). Postoperative intraocular pressure did not significantly change with either technique. Sufficient IOL stabilities were provided in all patients. Complications were similar in both techniques and none of the complications affected the patients’ vision.

CONCLUSIONS:
Postoperative visual acuity improvement, intraocular pressure changes, and complications were similar in both techniques.
Just-Noticeable Differences for Wavefront Aberrations Obtained With a Staircase Procedure
Authors: Jungnickel Hendrik , Weigel Daniel , Babovsky Holger , Kiessling Armin , Kowarschik Richard , Gebhardt Michael 
Published: February 2013

PURPOSE:
To explore the magnitude of aberrations that alter the subjective visual quality measurably. The suitability of a staircase procedure for threshold determination was investigated.

METHODS:

Spectacle correction (correction A) was achieved in 28 healthy eyes by an adaptive optics set-up, and additional astigmatism, coma, or trefoil was induced (correction B). Subjects observed a radial test pattern with noncyclopleged eyes using an artificial 5-mm pupil. They compared corrections A and B and identified the subjectively better correction. The magnitude of the aberration for each presentation varied according to the “Best PEST” staircase procedure. Just-noticeable difference (JND) was found after 30 presentations. Participants were divided into three groups, and the experiment was repeated under the following conditions: without modifications (
n
= 9), with a letter chart (
n
= 10), and with full correction of all aberrations (
n
= 9).

RESULTS:

Median JND was 0.091
μ
m for astigmatism, 0.059
μ
m for coma, and 0.108
μ
m for trefoil, with a large interindividual spread. Repeatability coefficient across the three aberrations was 0.095
μ
m. A significant correlation was found between JNDs and the residual aberrations (without the generated aberration) in astigmatism and coma. Differences between radial test pattern and letter chart and between spectacle correction and full correction were not significant.

CONCLUSIONS:
JNDs were lower for coma than for astigmatism and trefoil, depending on the magnitude of other residual aberrations, and showed large variations among subjects. Thus, the decision to correct more pronounced aberrations (eg, by wavefront-guided LASIK) should not depend on wavefront measurement results alone. A staircase procedure for determination of JNDs provides repeatable results.
Agreement Between Pentacam and IOLMaster in Patients Undergoing Toric IOL Implantation
Authors: Lee Bradford W. , Galor Anat , Feuer William J. , Pouyeh Bozorgmehr , Pelletier Jesse S. , Vaddavalli Pravin K. , Lemelman Benjamin T. , See Craig , Yoo Sonia H. 
Published: February 2013

PURPOSE:
To investigate inter-device agreement between the Pentacam (Optikgerate GmbH, Wetzlar, Germany) and IOLMaster (Carl Zeiss Meditec, Jena, Germany) in measuring corneal power, cylinder, and axis of astigmatism.

METHODS:
Retrospective case series reviewing the status of eyes after toric IOL implantation to evaluate inter-device agreement in measuring corneal power, cylinder, and axis of astigmatism.

RESULTS:

Forty-nine eyes from 41 patients were evaluated. Agreement for corneal power and cylinder were deemed good and moderate, with 95% limits of agreement of −1.02 to +1.13 and −1.37 to +1.09 diopters (D), respectively. Agreement for axis of astigmatism was only fair, with a mean absolute difference of 8.9 degrees (range: 0.3 to 37.7 degrees, standard deviation: 8.79 degrees). Thirty percent of eyes had a 10-degree or greater difference in axis measurements, and 13% of eyes had a 20-degree or greater difference in measurements. Analysis by multivariate logistic regression showed higher cylinder powers associated with discrepant corneal power measurements (odds ratio: 3.46,
P
= .02), and increasing age was associated with discrepant axis measurements (odds ratio: 1.09,
P
= .03). Overall, there was no significant difference in accuracy predicting postoperative spherical equivalent refraction.

CONCLUSIONS:
Pentacam and IOLMaster agree well for corneal power but less so for cylinder and axis of astigmatism and thus cannot be used interchangeably.
Objective Accommodation Measurement of the Crystalens HD Compared to Monofocal Intraocular Lenses
Authors: Zamora-Alejo Katherine V. , Moore Sacha Pierre , Parker Douglas G. A. , Ullrich Katja , Esterman Adrian , Goggin Michael 
Published: February 2013

PURPOSE:
Objective evaluation of accommodation with a bilateral accommodating intraocular lens (IOL) versus monofocal IOLs.

METHODS:
Patients received accommodating IOL (Crystalens HD; Bausch & Lomb, Rochester, NY) bilaterally after cataract surgery. These were compared to a matched group receiving monofocal IOLs. Preoperative and postoperative distance corrected distance, intermediate, and near vision were evaluated. Objective accommodation was measured with the WAM-5500 Binocular Autorefractor/Keratometer (Grand Seiko, Pty Ltd., Hiroshima, Japan).

RESULTS:

Nineteen patients were included. Ten received the Crystalens HD in both eyes and nine received one of three monofocal lenses in each eye. Mean postoperative distance corrected distance visual acuity was not statistically different between the two groups. Mean distance corrected intermediate vision was better in the Crystalens HD group (logMAR 0.24 ± 0.11 [control], logMAR 0.11 ± 0.10 [Crystalens HD],
P
= .033). The groups did not differ significantly for mean distance corrected near vision (logMAR 0.54 ± 0.12 [control], logMAR 0.42 ± 0.15 [Crystalens HD],
P
= .087). However, a significantly greater proportion of Crystalens HD eyes achieved 0.4 or 0.3 logMAR for near wearing their distance correction (
P
= .013). With distance correction, the mean spherical equivalent failed to show any myopia with accommodative effort in either group. Low contrast and low luminance contrast acuity were not significantly different.

CONCLUSION:
The Crystalens HD showed some benefit for intermediate visual function compared to the monofocal IOLs with both groups wearing full correction for distance. There were no significant signs of accommodation in either group.
Scleral Fixation of a One-Piece Toric Intraocular Lens
Authors: Emanuel Matthew E. , Randleman J. Bradley , Masket Samuel 
Published: February 2013

PURPOSE:
To describe a novel technique for toric intraocular lens (IOL) repositioning and fixation in the absence of adequate capsular support.

METHODS:
Case report and literature review.

RESULTS:
Two cases are presented with scleral fixation of a one-piece toric IOL (SN6AT series; Alcon Laboratories, Inc., Fort Worth, TX). In both cases, toric IOLs initially placed within the capsular bag became decentered due to poor capsular support. To avoid the potential complications of lens explantation and maintain the astigmatic benefits of the toric IOL, scleral fixation of the lenses was performed. The Hoffman technique was used to create reverse scleral pockets without conjunctival dissection. A 10-0 non-dissolvable suture was used to capture and then secure the lens haptics in a lasso-type fashion. Sutures were then buried within the previously created scleral pockets. Both patients had well-centered lenses postoperatively that remained stable at last follow-up, 30 months postoperatively.

CONCLUSION:
In the absence of adequate capsular support, scleral fixation is a viable option for one-piece toric IOL fixation to avoid IOL explantation.
Rotational Acetabular Osteotomy with Resection of the Capital Drop and Double Floor for Advanced Osteoarthritis of the Hip
Authors: Nakamura Yoshihide , Ohishi Hirotaka , Kishiya Masaki 
Published: February 2013

Rotational acetabular osteotomy (RAO) is an established joint preservation technique for early stage osteoarthritis (OA). To extend the application of RAO for advanced OA with significant osteophyte formation, we added intraarticular procedures including removal of the double floor and the capital drop to create medialisation and better coverage of the femoral head. The procedures were performed for seven joints with advanced OA. The average age of patients at surgery was 39 years. The follow-up periods ranged from five to 23 years. The capital drop was resected in five joints and both the capital drop and the double floor were removed in the other two joints. The Japanese Orthopaedic Association Hip Score improved from 53 points before surgery to 69 at the latest follow-up. The range of flexion was decreased. The centre-edge angle, Sharp angle and acetabular head index were significantly improved. The femoral head was medialised 5 mm by surgery. Three joints (43%) showed progression of osteoarthritis. One joint (14%) needed replacement at seven years after RAO. Resection of the capital drop and curtain osteophyte with RAO improved joint congruity and medialisation of the femoral head, but decreased the range of motion of the joint due to increased bony coverage. Progression of degeneration of the joint is not preventable. We abandoned these procedures for advanced osteoarthritis of the hip joint especially in older patients who were suitable for replacement arthroplasty.
L’impulsivité liée à la consommation et aux pratiques sexuelles chez des jeunes de la rue
Authors: El Khouri Myriam , Gagnon Jean 
Published: February 2013

Les jeunes de la rue présentent des comportements à risque liés à la consommation et à des comportements sexuels ayant des implications majeures sur leur santé et leur sécurité. En plus des problèmes de santé mentale, les traits impulsifs de la personnalité peuvent être un facteur de risque important par rapport à plusieurs de ces comportements problématiques.
La présente étude visait d’abord à dresser un portrait des jeunes de la rue, puis à vérifier la valeur de prédiction des traits impulsifs de la personnalité sur les comportements à risque au-delà des problèmes de santé mentale. 31 jeunes de la rue ont été soumis à l’UPPS-P Impulsive Behavior Scale mesurant cinq dimensions de l’impulsivité, ainsi qu’à d’autres instruments mesurant les problèmes de santé mentale (IBS), la consommation d’alcool et de drogues (DÉBA-Alcool/Drogues) et les comportements sexuels à risque (RBS).
Les jeunes de la rue rapportent plusieurs problèmes significatifs de santé mentale, plusieurs problématiques liées à la consommation d’alcool et de drogues, ainsi que plusieurs comportements sexuels à risque. Concernant la valeur de prédiction des traits impulsifs de la personnalité, les analyses de régression démontrent que l’Urgence positive contribue de manière unique à prédiction de la dépendance et des conséquences négatives associées à la consommation d’alcool alors que la Recherche de sensations n’est pas associée de manière significative à aucun des comportements à risque. De plus, seul le manque de Persévérance contribue de manière unique à la prédiction des conséquences négatives associées à la consommation de drogues, alors que seul le manque de Préméditation est associé significativement à la quantité d’alcool consommée. Ces résultats démontrent l’importance d’évaluer et d’intervenir sur les traits impulsifs de la personnalité de manière à augmenter l’efficacité des interventions de prévention des comportements à risque chez les jeunes de la rue.
Raman Spectroscopy of Proteins and Nucleoproteins
Authors: Nemecek Daniel , Stepanek Josef , Thomas George J. 
Published: February 2013

AbstractA protein Raman spectrum comprises discrete bands representing vibrational modes of the peptide backbone and its side chains. The spectral positions, intensities, and polarizations of the Raman bands are sensitive to protein secondary, tertiary, and quaternary structures and to side‐chain orientations and local environments. In favorable cases, the Raman spectrum serves as an empirical signature of protein three‐dimensional structure, intramolecular dynamics, and intermolecular interactions. Quantitative analysis of Raman spectral series can be further boosted by advanced statistical approaches of factor analysis that allow fitting of specific theoretical models while reducing the amount of analyzed data. Here, the strengths of Raman spectroscopy are illustrated by considering recent applications from the authors' work that address (1) subunit folding and recognition in assembly of the icosahedral bacteriophages, (2) orientations of subunit main chains and side chains in native filamentous viruses, (3) roles of cysteine hydrogen bonding in the folding, assembly, and function of virus structural proteins, and (4) structural determinants of protein/DNA recognition in gene regulatory complexes. Conventional Raman and polarized Raman techniques are surveyed. Curr. Protoc. Protein Sci. 71:17.8.1‐17.8.52. © 2013 by John Wiley & Sons, Inc.
Overview of Current Methods in Sedimentation Velocity and Sedimentation Equilibrium Analytical Ultracentrifugation
Authors: Zhao Huaying , Brautigam Chad A. , Ghirlando Rodolfo , Schuck Peter 
Published: February 2013

AbstractModern computational strategies have allowed for the direct modeling of the sedimentation process of heterogeneous mixtures, resulting in sedimentation velocity (SV) size‐distribution analyses with significantly improved detection limits and strongly enhanced resolution. These advances have transformed the practice of SV, rendering it the primary method of choice for most existing applications of analytical ultracentrifugation (AUC), such as the study of protein self‐ and hetero‐association, the study of membrane proteins, and applications in biotechnology. New global multisignal modeling and mass conservation approaches in SV and sedimentation equilibrium (SE), in conjunction with the effective‐particle framework for interpreting the sedimentation boundary structure of interacting systems, as well as tools for explicit modeling of the reaction/diffusion/sedimentation equations to experimental data, have led to more robust and more powerful strategies for the study of reversible protein interactions and multiprotein complexes. Furthermore, modern mathematical modeling capabilities have allowed for a detailed description of many experimental aspects of the acquired data, thus enabling novel experimental opportunities, with important implications for both sample preparation and data acquisition. The goal of the current unit is to describe the current tools for the study of soluble proteins, detergent‐solubilized membrane proteins and their interactions by SV and SE. Curr. Protoc. Protein Sci. 71:20.12.1‐20.12.49. © 2013 by John Wiley & Sons, Inc.
Determining the Conformational Stability of a Protein from Urea and Thermal Unfolding Curves
Authors: Grimsley Gerald R. , Trevino Saul R. , Thurlkill Richard L. , Scholtz J. Martin 
Published: February 2013

AbstractThis unit contains basic protocols for determining the conformational stability of a globular protein from either urea or thermal unfolding curves. Circular dichroism is the optical spectroscopic technique most commonly used to monitor protein unfolding. The protocols describe how to analyze data from an unfolding curve to obtain the thermodynamic parameters necessary to calculate conformational stability, and how to determine differences in stability between protein variants. Curr. Protoc. Protein Sci. 71:28.4.1‐28.4.14. © 2013 by John Wiley & Sons, Inc.
One‐Pot Oxidative Passerini Reaction of Alcohols Using a Magnetically Recyclable TEMPO under Metal‐ and Halogen‐Free Conditions
Authors: Karimi Babak , Farhangi Elham 
Published: February 2013

AbstractA novel domino oxidative Passerini three‐component reaction (OP‐3CR) has been successfully developed with either primary or secondary alcohols instead of their corresponding aldehydes or ketones by using a recyclable magnetic core‐shell nanoparticle supported TEMPO (2,2,6,6‐tetramethyl‐piperidin‐1‐oxyl) (MNST, 1). It has been shown that MNST is a highly effective and recyclable catalyst system in the metal‐ and halogen‐free aerobic, oxidative, three‐component Passerini reaction. To the best of our knowledge this method can be considered as the first example of a OP‐3CR of alcohols under metal‐ and halogen‐free reaction conditions. It should be also noted that there has been no precedent example of oxidative OP‐3CR of secondary alcohols to their corresponding α‐acyloxy carboxamides. The catalyst can be magnetically recycled and successfully reused in 14 subsequent reaction cycles with only slight decreases of its catalytic activity.
2‐(1‐Benzotriazolyl)pyridine: A Robust Bidentate Ligand for the Palladium‐Catalyzed CC (Suzuki, Heck, Fujiwara–Moritani, Sonogashira), CN and CS Coupling Reactions
Authors: Verma Akhilesh K. , Jha Rajeev R. , Chaudhary Ritu , Tiwari Rakesh K. , Danodia Abhinandan K. 
Published: February 2013

AbstractA new class of bidentate ligand, 1‐(pyridine‐2‐yl)‐1H‐benzo[d][1,2,3]triazole has been designed and employed for the palladium‐catalyzed CC (Suzuki, Heck, Fujiwara–Moritani, and Sonogashira), CN and CS coupling reactions. The ligand was found to be inexpensive, thermally stable, easy to synthesize from easily accessible starting materials on a multigram scale, show simplicity in use, and robustness in application, making this ligand effective for different coupling reactions. Suitably, the donor ability of the NN bond of the benzotriazole ring and lone pair of electrons on the N of the pyridine ring enhance the bidentate ability of the ligand.
Ethyl 2‐(tert‐Butoxycarbonyloxyimino)‐2‐cyanoacetate (Boc‐Oxyma) as Coupling Reagent for Racemization‐Free Esterification, Thioesterification, Amidation and Peptide Synthesis
Authors: Thalluri Kishore , Nadimpally Krishna Chaitanya , Chakravarty Maharishi Parasar , Paul Ashim , Mandal Bhubaneswar 
Published: February 2013

AbstractHere we report the synthesis and utility of ethyl 2‐(tert‐butoxycarbonyloxyimino)‐2‐cyanoacetate (Boc‐Oxyma) as an efficient coupling reagent for racemization‐free esterification, thioesterification, amidation reactions and peptide synthesis that uses equimolar amounts of acids and alcohols, thiols, amines or amino acids, respectively. Its application to solid phase as well as solution phase peptide synthesis is also demonstrated and a mechanistic investigation is discussed. Boc‐Oxyma is similar to the well known coupling agent COMU {1‐[1‐cyano‐2‐ethoxy‐2‐oxoethylideneaminooxy)‐dimethylaminomorpholino]uronium hexafluorophosphate} in terms of its high reactivity and mechanism of action. However, it is not only much easier to prepare, but also to recover and reuse, thereby generating far less chemical waste.
Lewis Acid‐Catalyzed Ring‐Opening Functionalizations of 1,4‐Epoxy‐1,4‐dihydronaphthalenes
Authors: Sawama Yoshinari , Ogata Yuta , Kawamoto Koichi , Satake Hiroyuki , Shibata Kyoshiro , Monguchi Yasunari , Sajiki Hironao , Kita Yasuyuki 
Published: February 2013

AbstractSince 1,4‐epoxy‐1,4‐dihydronaphthalenes are smoothly converted to 1‐naphthol derivatives via unstable cation intermediates formed by the acid‐catalyzed ring‐opening reaction of the 1,4‐epoxy moiety of 1,4‐epoxy‐1,4‐dihydronaphthalenes, their nucleophilic functionalization using the cation intermediates as an active species is extremely difficult. We have accomplished the Lewis acid‐catalyzed carbon‐carbon and carbon‐nitrogen bond formations associated with the ring‐opening of 1,4‐epoxy‐1,4‐dihydronaphthalenes using nucleophiles such as allyltrimethylsilanes, trimethylsilyl cyanide and trimetylsilyl azide, by using the stabilization effect of the cation intermediate based on the introduction of appropriate substituents into the bridgehead positions of 1,4‐epoxy‐1,4‐dihydronaphthalenes to give the corresponding unique and multifunctionalized naphthalene derivatives. The present reactions could provide excellent regioselective functionalization methods using unsymmetrical substrates, which are quite difficult to achieve using transition metal‐induced procedures.