bluuebunny/crossref_metadata_2025_split huggingface dataset:
Unsicherheit der Oberflächentemperaturmessung in Koordinatenmessgeräten
Authors: Augustin Silke , Fröhlich Thomas , Balzer Felix , Hölzel Sara 
Published: June 2024

Zusammenfassung
In der Präzisionslängenmesstechnik ist die Werkstücktemperatur aufgrund der Temperaturabhängigkeit der Materialeigenschaften eine wichtige Einflussgröße und liefert einen Beitrag zur Messunsicherheit. Neben den Einflüssen der Umgebung wie Temperaturschwankungen oder Bodenschwingungen auf das Koordinatenmessgerät selbst spielen auch die Einflüsse der Umgebung auf das Werkstück eine wichtige Rolle. Hierzu zählt neben den Temperaturschwankungen im Raum auch die jeweilige Vortemperierung der Werkstücke. Insbesondere führen die vorherige Bearbeitung und die Lagerung des Werkstücks zu Unterschieden zwischen der Oberflächen- und der Innentemperatur. Je größer die Genauigkeit der Temperaturbestimmung ist, desto kleiner sind die Messabweichungen. Deshalb wird zum Beispiel in Koordinatenmessgeräten während der Längenmessung die Temperatur im Messraum überwacht sowie die Temperaturen an der Oberfläche der Längenmesssysteme an den Messachsen und an der Oberfläche des Werkstücks erfasst und zur Onlinekorrektur der Messwerte verwendet. Zur Bestimmung der Werkstückoberflächentemperatur und der Kompensation dieser Temperatureinflüsse werden sowohl an den Werkstücken statisch, durch Magnete, befestigte Werkstücktemperatursensoren (Magnetfühler) verwendet als auch vor der Längenmessung automatisch einwechselbare Werkstücktemperatursensoren (Taster). Die Messunsicherheit dieser Temperatursensoren wird meist durch Kalibrierung in Flüssigkeitsbädern bestimmt. Dabei werden jedoch die Messunsicherheitsanteile, die durch das Aufsetzen auf die Oberfläche entstehen, nicht berücksichtigt. Diese Messunsicherheitsanteile wurden umfassend untersucht und werden im Beitrag vorgestellt.
Novel benzene sulfonamide-piperazine hybrid compounds: design, synthesis, antioxidant, enzyme inhibition activities and docking, ADME profiling studies
Authors: Buran Kerem , İnan Yiğit , Uba Abdullahi Ibrahim , Zengin Gökhan 
Published: June 2024

Abstract
Benzene sulfonamides are an important biological substituent for several activities. In this study, hybridization of benzene sulfonamide with piperazine derivatives were investigated for their antioxidant capacity and enzyme inhibitory potencies. Six molecules were synthesized and characterized. DPPH, ABTS, FRAP, CUPRAC, chelating and phosphomolybdemum assays were applied to evaluate antioxidant capacities. Results show that compounds have high antioxidant capacity and compound 4 has the best antioxidant activity among them. Compound 4 has higher antioxidant activity than references for FRAP (IC50: 0.08 mM), CUPRAC (IC50: 0.21 mM) and phosphomolybdenum (IC50: 0.22 mM) assays. Besides this, compound 4 has moderate DPPH and ABTS antioxidant capacity. Furthermore, enzyme inhibition activities of these molecules were investigated against AChE, BChE, tyrosinase, α-amylase and α-glucosidase enzymes. It was revealed that all compounds have good enzyme inhibitory potential except for α-amylase enzyme. The best inhibitory activities were observed for AChE with compound 5 the same value (IC50: 1.003 mM), for BChE with compounds 2 and 5 the same value (IC50: 1.008 mM), for tyrosinase compound 4 (IC50: 1.19 mM), and for α-glucosidase with compound 3 (IC50: 1.000 mM). Docking studies have been conducted with these molecules, and the results correlate well with the inhibitory assays.
Estudios sobre la organización y representación de la información en un contexto museológico.
Authors: De Paula Josefa , Cristina Leite da Silva Eva 
Published: June 2024

Registrar información hoy en día ha sido uno de los mayores desafíos, ya que la masa de información aumenta con el tiempo. Para utilizar registros de información es necesario que sean recuperables. La necesidad de organizar la información para recuperación ha sido objeto de estudios, que posibilitan diálogos entre campos del saber que tienen como instrumento la información, a saber, la Museología y las C. I. El presente trabajo presenta un levantamiento bibliográfico acerca de los estudios de Organización de la Información y Representación de la Información en un contexto museológico, con el objetivo de profundizar la comprensión de este tema, tanto la IO como la RI. Para ello,se adoptó como metodología el Análisis de Contenido de Bardin, desarrollado en la búsqueda de un conjunto de Anales que constituyen los mayores indexadores científico sobre el tema de este trabajo.Tratar de un posible diálogo de la Organización y Representación de la Información en los Museos, muestra la preocupación en explorar un tema poco expresivo en las bases de datos de eventos e investigaciones, si se relaciona con otros temas más recurrentes. El diálogo entre OI y RI para el acceso a la información en las instituciones museológicas facilita el acceso a la información tanto para el público que accede a estos lugares como para los profesionales que tienen contacto con la documentación museológica. Y, sin embargo, corrobora el desarrollo de las prácticas en el campo de la Museología, las C. I. y afines, a través de la difusión de la información.
Correlaciones de la teoría de la representación y la teoría de la intencionalidad: contribuciones a la encontrabilidad de la información
Authors: Alves Sanchez Fernanda , Ferreira de Castro Fabiano , Fernando Fernando , Borsetti Gregorio Vidotti Silvana Aparecida 
Published: June 2024

La teoría de la representación y la teoría de la Intencionalidad son conceptos emergentes de áreas del conocimiento como la psicología, la filosofía y las ciencias cognitivas. En el campo de la C. I., la representación de la información es un concepto ya consolidado; sin embargo, existen pocos trabajos sobre la teoría de la intencionalidad. Ante el paradigma poscustodial es posible afirmar que los sujetos informativos son individuos activos en el escenario socioinformativo, que aplican su intención de producir, organizar representar y buscar información en diferentes tipos de entornos informativos digitales. Esta investigación busca identificar las correlaciones existentes entre las teorías de la representación y de la intencionalidad en el contexto de la C. I., para verificar contribuciones a la encontrabilidad de la información, concepto cuyo abordaje incluye perspectivas teórico-prácticas para diseños, implementaciones y evaluaciones de entornos informativos. Es una investigación bibliográfica y exploratoria, con enfoque cualitativo en el análisis de bases de datos como el Portal de Periódicos de Capes, BRAPCI y Google Scholar. Entre los resultados de la investigación, fue posible identificar correlaciones en los conceptos de la teoría de la representación y de la intencionalidad, así como la importancia de los fundamentos de estos conceptos para potenciar la encontrabilidad de la información. Finalmente, se concluye que existe la necesidad de profundizar los estudios sobre la intencionalidad en el área de la C. I., dada la escasez de investigaciones, además de la relevancia que adquiere al posicionar el sujeto informativo dentro del concepto de encontrabilidad de la información.
Human gut microbiota as a potential source to treat obesity
Authors: D Sumitha , D Aboorva , Daniel Joseph C. , S Megala , P Gayathri 
Published: June 2024

The human gut microbiome is crucial to human health, illness, and diseases. These bacteria support the host system in a number of ways. Nonetheless, it appears that the species composition and alterations in the gut microbiota contribute to obesity. Screening of potential gut microbiota is inevitable at this point to address multiple health issues in the field of medical microbiology. Characterizing the gut microbiota of healthy individuals and determining the presence of inclinations to degrade cholesterol, which may aid in the treatment of obesity, were the objectives of the study.For this investigation 30 isolates were isolated from the faecal samples of the selected healthy individuals. On the basis of the morphological and biochemical features, 17 out of 30 isolates were selected for further studies. Based on colony morphology and biochemical tests 8 isolates were selected for screening of cholesterol degradation and lecithinase enzyme production. The ability of the selected isolates to withstand acidic pH was then examined throughout a variety of pH values. Additionally, their ability to withstand bile salts at various oxbile concentrations was examined. Based on the isolates' results, which demonstrate strong functional properties, 16s rRNA sequencing was used as a molecular methodology to identify them.The study's findings showed that the majority of the isolates that were chosen were non-motile, urease negative, catalase and oxidase negative. Lecithinase production was also negative in every isolate. Among the selected isolates 8 of them were selected for screening of cholesterol degradation. Two of the eight isolates that were chosen demonstrated the ability to degrade cholesterol, as evidenced by their production of two short chain fatty acids such as butyric and lactic acids. The ability to withstand different pH and bile concentrations were examined. High bile concentrations and low acid pH were conditions that both isolates could withstand and develop in. Based on the isolates' results, which demonstrate strong functional properties, 16s rRNA sequencing was used as a molecular methodology to identify them. It was determined that the isolates were MN294515 and MN535170.The majority of the cultures found in this investigation were gram positive bacteria. The two isolates of MN294515 and MN535170 can be further studied to determine which probiotic is more effective in treating obesity, a long-standing condition.
The impact of COVID-19 pandemic on seasonal influenza virus
Authors: Pandey Aparna , Pandey Pooja , Das Suman , Agarwal Priti , Pandey A.K. , Gupta Rajiv Mohan 
Published: June 2024

: The COVID-19 pandemic and subsequent implementation of non pharmaceutical interventions reduced transmission of Influenza viruses. The WHO has also noticed a drop-in influenza virus cases; however, it hasn't been precisely characterized. The prospect of concurrent influenza and COVID-19 outbreaks is a major concern for public health professionals. Therefore, in this study, we present our limited data on seasonal influenza activity during COVID -19 period (November 2021–October 2022). A retrospective analysis was conducted in 100 positive and 100 negative COVID-19 cases to look for co-infection with Influenza viruses. Influenza screening was performed with multiplex real-time RT-PCR using standardized techniques for Influenza H1N1/H3N2 with Inf-B on archived respiratory samples. A total of 8% Influenza cases were found with coinfection in only 05 cases denoting a drop of influenza infection during this period. Influenza A(H1N1) was the most common influenza virus followed by Influenza B (lineage not determined). The clinical outcomes of co-infections could not be anticipated and may worsen if novel COVID-19 variants continue to appear. The use of community mitigation measures for the COVID-19 pandemic, are likely to be effective in reducing the incidence of seasonal influenza.
Phenotypic detection of ESBL and Amp C beta lactamase among clinical isolates of Enterobacteriaceae
Authors: Thakar Vrushali , Gandavalli Brundha , Devhare Deepa , Modak Meera , Sawant Shailaja , Kumar Mahadevan , Bhatawadekar Sunita 
Published: June 2024

Emergence of ESBL & amp C β-Lactamase enzymes among clinical isolates of poses a significant public health concern. Antimicrobial agents like 3 generation cephalosporins, clavulanic acid, imipenem etc. can induce amp C enzyme production. Sometimes the automated antimicrobial susceptibility testing systems fails to detect Amp C phenotype due to presence of multiple resistance mechanisms in gram negative bacilli. To overcome such difficulty, the study was undertaken to detect the presence ESBL and Amp C enzymes among clinical isolates of by phenotypic methods. strains isolated from various clinical samples were included in the study. Strains resistant to two or three groups of antibiotics (MDR) were further tested for the presence of ESBL enzyme by combination disk method. Amp C enzymes were detected by cefoxitin- cloxacillin disc method.A total1059 strains were isolated from various clinical samples. Out of these, 170 MDR strains were further processed. ESBL enzymes were detected in 104 (61%) strains and Amp C in 35 (20.5%) strains. 26(15.2%) strains were co-producers. Detection of ESBL and Amp C enzymes will help clinician in choosing the right antimicrobial treatment for the patient. Routine reporting of presence of Amp C & ESBL enzymes by phenotypic methods can be easily implemented by clinical microbiology laboratory. Cefoxitin-cloxacillin disk test is simple & rapid method for detection of Amp C β- lactamase enzyme.
Occurrence and types of carbapenamase enzymes amongst enterobacterales and Pseudomonas spp. using automated phenotypic method
Authors: Dave Rajal Pranav , Chavan Sumit Sonaba , Angadi Kalpana Mohan 
Published: June 2024

The continuous rise of Carbapenem Resistant Organisms, considered as one of demanding public health issue. Carbapenemase producing organisms (CPO) can be detected by various molecular and phenotypic methods. Although molecular method shows higher accuracy, but is limited by relatively complex procedure and expensive regents. Thus, phenotypic methods considered as routine CPO detection method. Automated system Phoenix M50 (Becton & Dickinson) CARBA panels, provides the advantage of simultaneous identification and characterization of carbapenemase enzymes. A retrospective study was conducted for various clinical samples received at a tertiary care center in Western Maharashtra during a period of one year. The bacterial identification and antimicrobial susceptibility testing performed by automated system Phoenix M50 (Becton & Dickinson) CARBA panels. Isolates which flagged as carbapenemase producers were confirmed using modified carbapenemase inactivation method (mCIM) as a part of protocol. Among all isolates of enterobacterial and . 32% were carbapenemase producers. identified as predominant strain. Class B MBL was 46.4 % of isolates, consisting of appeared at 40% followed by at 35.5%. Class D beta-lactamase the second, the majority found in K.pneumoniae at 27.23%, followed by at 30 %. For Class A, 56 % followed by 26 % (n=67) isolates found in K.pneumoniae. The most isolates were Urine 16.6% followed by Pus 7.29 %, Respiratory 4% and blood 4%. A high occurrence of carbapenemase producers observed in the study is concerning. Moreover, most of them belonged to Class B MBLs, which demonstrated the need antibiotic stewardship and hospital infection control strategies to prevent their further spread.
Use of various substrate/ media for germ tube test (GTT) detection in Candida albicans and Candida dubliniensis from a tertiary care hospital
Authors: Kotgire Santosh , Hatkar Sunil 
Published: June 2024

In recent years, non-judicious use of broad spectrum antibiotics, corticosteroids, antineoplastic agents, immune suppressive drugs, widespread increased use of bone marrow and organ transplant, and unreasonable use of indwelling catheters have led to an increased incidence invasive candidiasis (IC). The germ tube test (GTT) is a well established, inexpensive, rapid and easy to dispense test used to identify . So the present study was conducted to assess the reliableness of different media for GTT production in and . A total of 102 and 09 strains were obtained from various clinical samples received at Department of Microbiology from a teaching institute and hospital located at west- central part of Maharashtra for a period of nine months. Medium that were employed for production of germ tube in and C.dubliniensis in the present study were trypticase soy broth, YEPD (Yeast Extract Peptone Dextrose) broth, Muller-Hinton agar/broth and peptone water which were assessed and compared with pooled human sera routinely used for detection of germ tube. For both the isolates human pooled serum showed 96.39% positivity followed by YEPD (yeast extract peptone dextrose) broth with 92.79% positivity, Trypticase soy broth showed 80.18% positivity, whereas Muller Hinton broth produced 67.56% positivity and least positivity was seen with Peptone water where only 45.04% of germ tube induction was observed. So our study clearly highlights that YEPD broth is better serum free media for germ tube production. Moreover, this medium is available commercially, is more stable, reliable, effective, is non biohazardous, convenient and cost effective alternative.
In-house Carba NP - II test to identify and differentiate carbapenemase-producing Gram-negative bacteria among various clinical isolates in comparison with immunochromatography assay
Authors: Tak Heena , Amber Tabassum , Kapaganty Vamsi Chakradhar 
Published: June 2024

Resistance to Carbapenems has increased drastically resulting in ineffective treatment, prolonged hospital-stay, increased morbidity and mortality. A cost-effective in-house test that can differentiate carbapenemase enzymes belonging to different Amblers Class can emerge as an important tool in middle and low-income countries for guiding the clinicians in selecting the most appropriate antibacterial therapy. Cost effective commercial ICT kits are also available now for the same use.1. To adapt an in-house test that can identify and differentiate Ambler class carbapenemase enzymes among the clinical isolates of multi-drug resistant Gram-negative bacteria (GNB); 2. To evaluate the commercially available immunochromatography (ICT) lateral flow assay of carbapenemase detection in comparison to in-house Carba NP – II testA prospective study conducted in the Department of Microbiology of NRI Institute of Medical Sciences, Visakhapatnam. All GNB isolates irrespective of source, age and gender, were considered in the study. A total of 565 GNB isolates were obtained, which were subsequently tested for Meropenem resistance by routine antimicrobial susceptibility test (AST), out of which 195 isolates were further tested for carbapenemase resistance by in-house Carba NP - II test and ICT (Bio-State Inc).Out of 565 isolates, 195 were Meropenem resistant, 120 belonged to Class B and 75 to Class D by in-house modified Carba NP-II test. In ICT, 117 belonged to Class B and 73 to Class D and 5 isolates showed both the enzymes of Class B and D. No class A enzyme was detected in our study by either method.Carba NP - II Test is a reliable and cost-effective test with similar results in comparison to commercially available ICT.
Microbiological profile and antimicrobial susceptibility patterns of blood stream infections in febrile neutropenic patients with hematological malignancies in a tertiary care hospital, Kolkata
Authors: Ganguly Bhattacharjee Swagata , Mandal Sayan , Mullick Soma Sil , Bhunia Somnath , Kundu Suman , Banik Ankita , Mallick Tanvi , Behera Kishor Kumar 
Published: June 2024

Blood stream infection (BSI) in febrile neutropenic (FN) patients with hematological malignancy is a common manifestation with high mortality rate. To reduce mortality knowledge of pathogens causing BSI and their antimicrobial susceptibility patterns are required for timely initiation of appropriate antimicrobial therapy. This study was aimed to characterize the pathogenic spectrum and antimicrobial resistance patterns of BSI in these patients. In this cross-sectional study patients admitted in the Hematology department over a period of one year with laboratory confirmed positive blood cultures were enrolled. Information regarding demographic profiles and microbiological profiles were recorded. Standard procedures were applied to identify the isolates and their resistance patterns in positive blood culture. Data was collected and analyzed on MS-Excel sheet with various charts and tables. During the study period of one year 198 episodes of BSI recorded in 147 FN patients. Majority of isolates were Gram-negative bacilli (GNB: n=107, 54.04%). Among GNB (n=34, 31.77%) was most frequently isolated and in Gram-positive cocci (GPC) majority isolated was (n=37, 62.71%). (n=12, 37.5%) was the commonest fungal pathogen isolated. Susceptibility to penicillin, clindamycin and quinolones were least among GPC. Among GNB higher resistance patterns were observed against ceftazidime, cefepime, cefoperazone-sulbactam, piperacillin-tazobactam and meropenem. All isolates were resistant to fluconazole. This study revealed a significant increase in proportion of Gram-negative non-fermenting bacteria (GNNFB). These findings highlight the necessity for regular revision of institutional antimicrobial policy which will reduce mortality as well as development of resistant pathogens.
The Influence of Tiktok Videos in Increasing Students’ Pronunciation Ability
Authors: Safila Risa 
Published: June 2024

This study intended to show the effect of TikTok videos on students’ pronunciation skills . A quasi-experimental study design was used in this study. Students from MAN 2 Probolinggo participated in this study, 20 students consist as an experimental class and consist of 20 students as a control class. The results of this study showed a significant difference between students using TikTok videos as media learning and those using traditional strategies. Post-test results revealed that there was a significant effect of post-treatment on experimental class. Independent test results show that TikTok videos have a significant impact on students' pronunciation skills. However, the mean pretest scores of the experimental class are higher than the control class. It can be concluded that TikTok videos have a positive effect on students' pronunciation ability and are accepted as an effective learning medium to improve students' pronunciation ability.
Utilizing Canva Platform to Improve Students’ Achievement in English Learning and Teaching
Authors: Maria Bernadin , Februati Noenoek , Yuliatin Umi 
Published: June 2024

The issue that this research focuses was the students’ low achievement in learning English. This followed the condition where the students showed their unpreparedness in attending the English learning and teaching program. To address this problem, the effort to improve the students’ achievement was made by utilizing Canva platform to redesign the present English for Specific Purposes material. This research, therefore, was conducted with the aim of determining whether the students improved their achievement when they used the English learning and teaching material designed with Canva platform. To prove the existence of such improvement, the data was collected from the same group of research subjects consisting of 76 students of Polytechnic of Energy and Mineral through the pre-test and post-test. Both data was, then, compared and the result of the comparison was t = 4.22 which equaled to p-value= 0.000. Since the significance level α = 0.05, it could be said that Null Hypothesis / H0, there was no improvement of the students’ achievement when they used Canva-based designed material, was rejected because p-value α. It meant that the Alternative Hypothesis / H1, there was an improvement of the students’ achievement when they used Canva-based designed material, was accepted