bluuebunny/crossref_metadata_2025_split huggingface dataset:
'That They All May Be One'
Authors: Molitor Dom Raphael 
Published: August 2024

‘Ut Omnes Unum Sint.’ Why was it that our Lord did not include this prayer among the petitions of the Our Father? Surely it was because its content is too holy and its meaning too delicate and full of mystery. This petition could only be presented to the Father with the required purity and value by the lips of our High Priest, the God-Man, and by the infinite love of his heart.Ut omnes unum sint. The prophetic eye of Jesus scans time and eternity. The faithful appear before him in their millions—men of the most diverse tongues and lands approach him, desirous to find in him deliverance and eternal salvation, love and peace, eager to live according to his will and example, to be like him in all things, forming a host of glittering stars. Each One in himself, separated from the rest, is a world of his own.
The Little Brothers of Jesus
Authors: Anson Peter F. 
Published: August 2024

Nobody who passes by that shabby little house in a back street in the poorest quarter of the fishing port of Concarneau would suspect that two rooms on its first floor make up the ‘monastery’ of a small contemplative religious community. None of the many summer visitors to what is also a popular Breton holiday resort would ever guess that the four young men, garbed as labourers or fishermen, who might be Noticed entering or leaving this house are professed religious, following a rule of life which, in its own way, is as strict as and perhaps harder than that of Carthusian or Cistercian monks.One of these Little Brothers of Jesus was waiting for me at the barrier of Concarneau station when I arrived there on a July evening this summer. I managed to spot him in the crowd because of a small badge, composed of a red cross and heart, pinned on to the much washed open-necked khaki shirt he was wearing.
Cyprian the Christian
Authors: Durnford G. M. 
Published: August 2024

It is a deplorable loss to Catholic reading that ‘The Library of the Fathers', the classic series of translations edited by Pusey, Keble and Newman should have been allowed to remain unfinished and long out of print. Moreover, it is already more than a century since these vernacular versions first appeared, and they have never been surpassed: fine scholarship and loving care alike went to their making, and when we pray for England's return to the Faith, the re-availability in our language of that patristic literature whose istudy birmght the greatest of English converts into the Church should be covered by our intention.Among the first members of the series, in 1839 to be exact, there appeared the ‘Treatises of Saint Cyprian' the third-century bishop and martyr of Carthage, to be followed in due course by the companion volume of his Epistles.
Spiritual Progress
Authors: Gardeil A. 
Published: August 2024

The spiritual life is the life we live in Christ. We are alive in him because he is the head of the body of which we are living members. From him we get light, life, movement, His ceaseless graces flow from the sacraments, those living streams circulating within the veins of his mystical body. Chief among these graces are the Church's teaching, the Liturgy, and then the words and living example of the saints who share with us membership of the same body which is Christ.The Church is alive and life-giving and makes alive all those who are its living members: the branches live in and by the life of the true Vine. All the mysterious and wonderful influences that flood the Christian soul have their source in Christ now gloriously alive in heaven. From the heart of his divinity he sends us the Holy Ghost, given to us as an abounding personal gift.
Love of the Word
Authors: Pepler Conrad 
Published: August 2024

We cannot take leave of Richard Rolle without listening to his principal message and the one which is the dominant theme of the illuminative way. His greatest work was on ‘The Fire of Love’, his most unique mystical experience was the burning of love in his breast, and his poetry which did more than anything else to spread his spirit among his contemporaries is concerned with the sweet love of Jesus, his Spouse. Love is thought, with great desire of a fair Loving.The illumination as we have seen comes principally from the shining of the Gifts of the Holy Spirit in the beginning of infused contemplation. But this light cannot of course be separated from the Word whose function it is to enlighten the understanding. Indeed the activities of the second and third Persons of the Blessed Trinity in this respect cannot be separated; it is the one action of the Verbum spirans amorem.
Aspects of the Chalice
Authors: Baldwin Dominic 
Published: August 2024

Though a study of the liturgy is undertaken to find the meaning of, to get behind, so to speak, the elements (the words, actions, things) of the Church's ceremonies, it may seem a little strange that we should look for a symbolical meaning of necessary a receptacle as a chalice or cup in any religious rite in which a liquid is used. But man's knowledge begins with the senses. Metaphors, sensible (corporeal) representaons or similitudes are not only natural to man but naturally pleasing to him—for which reason St Thomas says, it is fitting that pmtual things are given to us by means of metaphors drawn from corporeal things, sub metaphoris corporalium.Man has always tended to express his religious or spiritual ideas in terms of his physical environment and his reactions to it, in terms of things that are vital and familiar to him. Though this anniiarity has perhaps clouded the modern sophisticated mind, the Principle remains fundamentally true.
The Divine Office as a Method of Prayer
Authors: Griffiths Bede 
Published: August 2024

A priest of my acquaintance once told me that when he was a young religious, he had had a great devotion to the divine office. In order to get the best out of it, he decided to make a careful study of the psalms. So he got out the best commentaries and studied their meaning in Latin and Hebrew; and when he had finished, he found that the psalms had ceased to have any meaning to him as prayer at all. This is, perhaps, an extreme example, but it illustrates a fact of great importance, namely, that prayer is not necessarily an exercise of discursive thought, and that study of a certain kind can be an obstacle rather than an assistance to prayer.There is no doubt that for a great many priests and religious, if not the majority, the divine office is not a congenial method of prayer. It is a duty which has to be performed, which has its own special grace and virtue, but it is not generally felt as a personal method of prayer and approach to God.
The Liturgy of the Sacrament of Penance
Authors: Hennig John 
Published: August 2024

One of the most significant features in modern Church life is no doubt the interest taken by the laity in the liturgy. The liturgies of the Mass and of the Sacraments of Baptism, Holy Orders and Extreme Unction in particular invite us by the variety of their ceremonies and texts to follow them in all their details and, in fact, are well known in both their historical development and their present form. There is perhaps one lacuna in this liturgical discussion. Apart from the Sacrament of the Holy Eucharist, no Sacrament is more frequently received by us than is the Sacrament of Penance; and yet we rarely hear of the liturgy of this Sacrament and its history. In fact, some Catholics might be surprised at the application of the term ‘liturgy’ to the Sacrament of Penance.In his Encyclical The Mystical Body of Christ, the Holy Father has complained of a neglect, at present found in many countries, of the Sacrament of Penance.
Do pandemics reduce support for democracy? A survey experiment in Myanmar
Authors: Mon Swe Oo , Yamada Kyohei 
Published: August 2024

AbstractThis paper focuses on people's attitudes towards democracy and authoritarian regimes in Myanmar and whether the extent to which they prefer democracy is moderated by the severity of the coronavirus disease-2019 (COVID-19) pandemic. If people view the authoritarian regime's capacity to take swift action favourably, their opposition to it may be lower. We explored this hypothesis by conducting a survey of 756 individuals in Myanmar in June 2022 that incorporated a vignette experiment. A hypothetical scenario of Myanmar society in 2023 was presented with a two-by-two design – the conditions of the government (election is restored or not) and the pandemic situation (good or bad) were randomly varied, and the respondents were asked to report their favourability of the hypothetical scenario. The results reveal: (1) regardless of the pandemic condition, respondents prefer democracy to authoritarian regimes by a wide margin; and (2) the extent to which democracy is preferred is lower when the COVID-19 condition is more severe. Similar results were obtained from supplementary analyses using a conjoint experiment.
Anthropogenic Influence Has Increased the Nighttime Heat Stress Risks in Eastern China
Authors: He Wenyue , Chen Huopo 
Published: August 2024

AbstractNights with high temperatures and humidity often bring more fatal consequences during the human sleeping process. A significantly increasing trend in the intensity and frequency of humid‐heat nights has been observed in eastern China from 1961 to 2014. Detection analyses show that the fingerprinting of anthropogenic forcing, in which the greenhouse gas forcing is critical, can be identified for changes in the humid‐heat nights in eastern China. However, the roles of anthropogenic aerosols and external natural forcings cannot be detected, and their effects on the observed changes in humid‐heat nights over eastern China are generally negligible. Under different warming scenarios, there is a projected continuation of increasing intensity and frequency of humid‐heat nights, although the magnitudes are reduced after constraining. In eastern China, the areal mean intensity of humid‐heat nights is projected to increase by approximately 0.9, 1.5, 2.5, and 3.5°C (relative to 1995–2014) for 1.5, 2.0, 3.0, and 4.0°C global warming, while the occurrence of extreme humid‐heat night is 1.1, 1.2, 1.2, and 1.3 times more than the current period. Moreover, the population exposed to humid‐heat nights in eastern China, particularly in the northern regions, is expected to increase in the future. Our results enhance the understanding of the potential risks of humid‐heat nights, which is critical for climate‐change policy in China.
An Emulator of Stratocumulus Cloud Response to Two Cloud‐Controlling Factors Accounting for Internal Variability
Authors: Sansom Rachel W. N. , Carslaw Ken S. , Johnson Jill S. , Lee Lindsay 
Published: August 2024

AbstractLarge uncertainties persist in modeling shallow, low clouds because of many interacting nonlinear processes and multiple cloud‐controlling environmental factors. In addition, sharp changes in behavior occur when environmental thresholds are met. Model studies that follow a traditional approach of exploring the effects of factors “one‐at‐a‐time” are unable to capture interactions between factors. We simulate a stratocumulus cloud based on the Second Dynamics and Chemistry of Marine Stratocumulus field study using a large‐eddy simulation model coupled with a two‐moment cloud microphysics scheme. The simulations are used to train a Gaussian process emulator, which we then use to visualize the relationships between two cloud‐controlling factors and domain‐averaged cloud properties. Only 29 model simulations were required to train the emulators, which then predicted cloud properties at thousands of new combinations of the two factors. Emulator response surfaces of cloud liquid water path and cloud fraction show two behavioral regimes, one of thin and patchy yet steady stratocumulus and one of thick, growing stratocumulus with cloud fraction near 1. Internal variability (initial‐condition uncertainty) creates unrealistic “bumpy” response surfaces. However, we show that the variability causing the bumpiness can be characterized in an emulator “nugget term” that is adjusted to match the distribution of a small number of initial‐condition ensemble simulations at various points on the surface, thereby allowing a smoother, deterministic response surface to be constructed. Accounting for variability allows the transition between regimes, and the joint interactions of parameters, to be visualized in a more deterministic way that has not been done before.
Coordinated Geostationary, Multispectral Satellite Observations Are Critical for Climate and Air Quality Progress
Authors: Millet Dylan B. , Palmer Paul I. , Levelt Pieternel F. , Gallardo Laura , Shikwambana Lerato 
Published: August 2024

AbstractSatellite observations are critical for air quality and climate monitoring, and for developing the process understanding needed for reliable planning and predictions. Our current space‐based observing system stands at a crossroads with the early missions approaching their end‐of‐life. We articulate the challenges and needs to sustain and develop these environmental records into the future, focusing specifically on observations of gas‐phase atmospheric composition.
Stratospheric Chlorine Processing After the Unprecedented Hunga Tonga Eruption
Authors: Zhang Jun , Wang Peidong , Kinnison Douglas , Solomon Susan , Guan Jian , Stone Kane , Zhu Yunqian 
Published: August 2024

AbstractFollowing the Hunga Tonga–Hunga Ha'apai (HTHH) eruption in January 2022, significant reductions in stratospheric hydrochloric acid (HCl) were observed in the Southern Hemisphere mid‐latitudes during the latter half of 2022, suggesting potential chlorine activation. The objective of this study is to comprehensively understand the loss of HCl in the aftermath of HTHH. Satellite measurements and a global chemistry‐climate model are employed for the analysis. We find strong agreement of 2022 anomalies between the modeled and the measured data. The observed tracer‐tracer relations between nitrous oxide (N2O) and HCl indicate a significant role of chemical processing in the observed HCl reduction, especially during the austral winter of 2022. Further examining the roles of chlorine gas‐phase and heterogeneous chemistry, we find that heterogeneous chemistry emerges as the primary driver for the chemical loss of HCl, and the reaction between hypobromous acid (HOBr) and HCl on sulfate aerosols is the dominant loss process.
Increased somatic mosaicism in autosomal and X chromosomes for suicide death
Authors: Otsuka Ikuo , Uchiyama Shunsuke , Shirai Toshiyuki , Liu Xiaoxi , Takahashi Motonori , Kamatani Yoichiro , Terao Chikashi , Hishimoto Akitoyo 
Published: August 2024

Abstract
Mosaic chromosomal alterations (mCAs) are classified as mosaic deletions (loss), copy-neutral loss of heterozygosity (CN-LOH), and duplications (gain), attracting special attention as biological aging-related acquired genetic alterations. While these mCAs have been linked with aging and various diseases, no study has investigated their association with suicide risk which is associated with abnormal biological aging. Here, we examined the association between suicide deaths and mCAs, including mosaic loss of the X (mLOX) and Y chromosomes, by leveraging blood-derived single nucleotide polymorphism-array data. The first (410 suicide decedents and 88,870 controls) and the second (363 suicide decedents and 88,870 controls) cohorts were analyzed and integrated using meta-analyses (773 suicide decedents and 177,740 controls). Total mCAs in autosomal chromosomes were significantly increased in suicide (p = 1.28 × 10−6, odds ratio [OR] = 1.78), mostly driven by loss (p = 4.05 × 10−9, OR = 2.70) and gain (p = 1.08 × 10−3, OR = 2.23). mLOX were significantly increased in female suicide (p = 2.66 × 10−21, OR = 4.00). The directions of effects of all mCAs in autosomal and sex chromosomes on suicide were the same in the first and second sets. Subgroup analyses suggest that our findings were mostly driven by suicide itself, and not confounded by comorbid psychiatric disorders or physical diseases, smoking status, sample location, or postmortem sample status. In conclusion, we provide the first evidence for aberrant mCAs in somatic autosomal and X chromosomes in suicide, which may contribute to an improved understanding of the genomic pathophysiology underlying suicide.
Dual pathway inhibition with faricimab for previously treated neovascular age-related macular degeneration and diabetic macular oedema: guidance from a UK panel of retina specialists
Authors: Downey Louise , Sivaprasad Sobha , Chhabra Ramandeep , Bailey Clare , Chakrabarti Soma , Elsherbiny Samer , Patel Jignesh , Silvestri Giuliana , Watson Sarah-Lucie , Williams Gwyn , Parker Antony , Khokhar Saima , Lotery Andrew 
Published: August 2024

Abstract
Background/objectives
Some eyes with neovascular age-related macular degeneration (nAMD) and centre-involving diabetic macular oedema (DMO) fail to respond sufficiently or lose response over time to standard of care intravitreal anti-vascular endothelial growth factor (anti-VEGF) therapy. This paper explores clinical scenarios for switching to dual action angiopoietin-2 (Ang-2)/VEGF-A inhibitor faricimab (Vabysmo, Roche Products Limited) in previously anti-VEGF-treated patients.

Methods
A national steering group meeting of UK retina specialists was held in London on 27 October 2023. Clinician practice and experience were reviewed together with pivotal clinical trial data and early findings from real-world settings. Roche Products Limited facilitated and funded the meeting.

Results
While there is no standardised protocol for identifying suboptimal response, the authors review relevant clinical biomarkers of disease activity used in routine clinical practice to determine patient response and guide treatment decisions. Common reasons identified for considering a change of treatment were lack of efficacy demonstrated by suboptimal anatomic or visual improvement and insufficient durability of response. The panel outline strategies for switching to faricimab among eligible patients with a prior anti-VEGF treatment history, with initial monthly loading doses or maintaining the previous treatment interval before attempting to extend, that may be integrated into current treat-and-extend (T&E) clinical pathways for treating patients with nAMD and DMO. General considerations for switching between treatments are also reviewed.

Conclusion
Clinicians may consider a treatment switch to faricimab in nAMD and DMO patients who have suboptimal disease control or insufficient durability of response on initial anti-VEGF therapy.
Energetics and quantumness of Fano coherence generation
Authors: Donati Ludovica , Cataliotti Francesco Saverio , Gherardini Stefano 
Published: August 2024

AbstractIn a multi-level quantum system Fano coherences stand for the formation of quantum coherences due to the interaction with the continuum of modes characterizing an incoherent process. In this paper we propose a V-type three-level quantum system on which we certify the presence of genuinely quantum traits underlying the generation of Fano coherences. We do this by determining work conditions that allows for the loss of positivity of the Kirkwood-Dirac quasiprobability distribution of the stochastic energy changes within the discrete system. We also show the existence of nonequilibrium regimes where the generation of Fano coherences leads to a non-negligible excess energy given by the amount of energy that is left over with respect to the energy of the system at the beginning of the transformation. Excess energy is attained provided the initial state of the discrete system is in a superposition of the energy eigenbasis. We conclude the paper by studying the thermodynamic efficiency of the whole process.
miR-21, miR-29a, and miR-106b: serum and tissue biomarkers with diagnostic potential in metastatic testicular cancer
Authors: Ujfaludi Zsuzsanna , Fazekas Fruzsina , Biró Krisztina , Oláh-Németh Orsolya , Buzogany Istvan , Sükösd Farkas , Beöthe Tamás , Pankotai Tibor 
Published: August 2024

AbstractThe imperative need for sensitive and precise tools is underscored in cancer diagnostics, with biomarkers playing a pivotal role in facilitating early detection and tumor diagnosis. Despite their classical pathological classification, testicular tumors lack valuable markers, emphasizing the necessity to identify and apply serum tumor markers in clinical management. Unfortunately, existing biomarkers exhibit limited sensitivities and specificities. Recent years have witnessed the discovery of novel RNA molecules, presenting a potential breakthrough as diagnostic tools and promising biomarkers. This report presents compelling evidence supporting the detection of early testicular cancer by applying a set of nine microRNAs (miRNAs), establishing them as valuable serum biomarkers for diagnosis. We developed a standardized serum-based measurement protocol and conducted comprehensive statistical analyses on the dataset to underscore the diagnostic accuracy of the miRNA pool. Notably, with a sensitivity exceeding 93%, miR-21, miR-29a, and miR-106b surpass classical serum tumor markers in the context of testicular cancer. Specifically, these miRNAs are poised to enhance clinical decision-making in testicular cancer detection and hold the potential for assessing tumor growth in monitoring chemotherapy outcomes.
M2 macrophage-derived lncRNA NORAD in EVs promotes NSCLC progression via miR-520g-3p/SMIM22/GALE axis
Authors: Zhao Qingtao , Li Bin , Zhang Xiaopeng , Zhao Huanfen , Xue Wenfei , Yuan Zheng , Xu Shun , Duan Guochen 
Published: August 2024

AbstractNon-small cell lung cancer (NSCLC) constitutes the majority of lung cancer cases, accounting for over 80%. RNAs in EVs play a pivotal role in various biological and pathological processes mediated by extracellular vesicle (EV). Long non-coding RNAs (lncRNAs) are widely associated with cancer-related functions, including cell proliferation, migration, invasion, and drug resistance. Tumor-associated macrophages are recognized as pivotal contributors to tumorigenesis. Given these insights, this study aims to uncover the impact of lncRNA NORAD in EVs derived from M2 macrophages in NSCLC cell lines and xenograft mouse models of NSCLC. EVs were meticulously isolated and verified based on their morphology and specific biomarkers. The interaction between lncRNA NORAD and SMIM22 was investigated using immunoprecipitation. The influence of SMIM22/GALE or lncRNA NORAD in EVs on glycolysis was assessed in NSCLC cell lines. Additionally, we evaluated the effects of M2 macrophage-derived lncRNA NORAD in EVs on cell proliferation and apoptosis through colony formation and flow cytometry assays. Furthermore, the impact of M2 macrophage-derived lncRNA NORAD in EVs on tumor growth was confirmed using xenograft tumor animal models. The results underscored the potential role of M2 macrophage-derived lncRNA NORAD in EVs in NSCLC. SMIM22/GALE promoted glycolysis and the proliferation of NSCLC cells. Furthermore, lncRNA NORAD in EVs targeted SMIM22 and miR-520g-3p in NSCLC cells. Notably, lncRNA NORAD in EVs promoted the proliferation of NSCLC cells and facilitated NSCLC tumor growth through the miR-520g-3p axis. In conclusion, M2 macrophage-derived lncRNA NORAD in EVs promotes NSCLC progression through the miR-520g-3p/SMIM22/GALE axis.
Synthesis of the novel (BiO)4CO3(OH)2/BiOBr heterostructure with enhanced photocatalytic reduction of Cr(vi) and degradation of tetracycline
Authors: Li Yuchen , Zhang Yi , Zhou Ze Yu , Peng Bin , Peng Yin 
Published: August 2024

The (BiO)4CO3(OH)2/BiOBr heterojunction with outstanding photocatalytic performance was developed using (BiO)4CO3(OH)2 and HBr acid as raw materials.