bluuebunny/crossref_metadata_2025_split huggingface dataset:
885 – Evaluation Of Personality Of Patients With Dysmenorrhea With The Help Of The Millon's Clinical Multiaxial Inventory Iii
Authors: Pirkalani K.K. , Talaee Rad Z. 
Published: July 2013

IntroductionDysmenorrhea is a pain variant syndrome with wide range of manifestations and intensity even in the same person. Like other pain variants it seems to be very subjective and personality dependent.ObjectiveDespite uniform molecular basis of dysmenorrhea further risk factors are needed to be clarified.AimTo find out which subgroup of patients express more severe symptoms and need stronger treatments.MethodsHundred and twenty consecutive patients (half reported dysmenorrhea of some concern while the other half of no or minor concern) were evaluated with the Millon's Clinical Multiaxial inventory MSMI-III. The former group used routinely drugs for dysmenorrhea in a PRN basis and some used medications as prophylaxis. The former group was free to use psychoactive medication but people using psychoactive medications were excluded from the latter group. Dysmenorrhea was not graded according to severity and stress was laid on personal view about the matter.ResultPatients with dysmenorrhea had higher scores in passive aggressive, borderline, avoidant, dependent, histrionic and obsessive personality scales (p< 0.04) while patients without dysmenorrhea showed higher scores in narcissistic, schizoid, schizotypal, paranoid personality scales (p< 0.07).DiscussionDysmenorrhea patients show lower pain threshold, increased preoccupation about disease and higher rates of menstrual irregularity, are more regularly visited by their gynecologist, ask more questions about cancer and are more prone to adjustment disorder. We conclude that although the pathophysiological basis of dysmenorrhea can purely be attributed to organic and molecular landmarks the expression of pain and reaction to it is personality dependent.
886 – A Case Series Of Depressed Elderly (>64 Years) Presenting In a General Hospital In Singapore
Authors: Cheang K.M. , Tan L.P.L. 
Published: July 2013

IntroductionA recent national survey highlighted the considerable treatment gap for depression (59.6%) in modern Singapore. Asians tend to focus on physical features of a disease than the psychological ones, which might contribute to the relative lack of disease pick up by physicians. Literature suggests a distinct clinical entity of depression among the elderly, with a different clinical presentation from adults.ObjectivesThis retrospective case series was undertaken to understand the clinical features and management decisions of elderly patients presenting with depression in Singapore.AimsTo describe the demographics, clinical presentation, psychiatric and medical co-morbidities, and management decisions of depression in the elderly.MethodsInter-departmental referrals to the Department of Psychological Medicine of Tan Tock Seng Hospital from 1/1/2011 to 31/3/2011 for the management of patients ages above 64 with the diagnosis of depression were collated for case description.ResultsA total of 40 inpatients ages 65 to 104 years (mean 76.2 years) were recruited. 14 (35%) were male and 26 (65%) were female. 70% of them does not have a co-existing psychiatric diagnosis. The highest number of referrals were form the department of General Medicine (42.5%) followed by Geriatric Medicine (25%). Most of the elderly were admitted for infection (20%), followed by equal proportions of those admitted for cardiovascular problems (12.5%), recurrent falls (12.5%), psychiatric issues (12.5%), and orthopedic problems (12.5%).ConclusionsAs the population of Singapore ages, clinicians should be mindful that depression often co-exist with medical co-morbidities, and the complex interaction amongst the two entities.
894 – Can rTMS Be An Alternative Of Psychopharmacology In Epilepsy?
Authors: Kistsen V. , Evstigneev V. 
Published: July 2013

The aim of our study was optimization of hippocampal activity in epilepsy patients by rTMS with modality which was detected in different seizures models and calculated in mathematic model to determinate of parameters for hippocampal targeted stimulation.MethodsSixty eight patients with epilepsy (mean age 28.1±2.9 years) were studied (DTI MRI, EEG-mapping, neuropsychological tests). Patients of control group (n=32) took AED at therapeutic doses and had side effects at 97%. Patients of experimental group (n=36) treated with low AED doses and 1 Hz rTMS over the temporal lobe with focusing on hippocamp projection.ResultsThere were depression at 48.5% and high anxiety level at 40% of examined patients what correlated with position of epileptic focus in left hemisphere (OR=6.7, p=0.045), presenting of “spike-slow wave” complexes (OR=9.6, p=0.0001), female gender (OR=4.2, p=0.04) and focal onset of seizure (OR=2.1, p=0.039). Dynamic monitoring at control group did not reveal any differences at epilepsy course during 12 monthes.At experimental group significant decreasing of seizure frequency and severity during 12 weeks after rTMS onset was determined. Antidepressive and anxiety effect was obtained at 46% patients to tenth procedure (p=0.004). Increasing of quality of life was registered by QOLIE-31 (p< 0.05). Received effect remained during six monthes in 40% experimental patients (p< 0.05).ConclusionsThereby, including of rTMS into combined epilepsy therapy with low doses of anticonvulsants has a determining function and leads to significant antiepileptic effect improves the psychological condition, quality of life of these patients and allows avoiding of psychotropic drugs prescription.
896 – Prevalence And Age-of-onset Distributions Of Suicidal Thoughts, Plans And Attempts Among Students Of Nine Public Universities In Wroclaw, Poland: Wmh-cidi Findings
Authors: Zagdańska M.J. , Kiejna A. 
Published: July 2013

Suicidality among university students represents an important and growing public health concern for which epidemiological data are needed.This study aimed to estimate the prevalence of suicide thoughts, plans and attempts among students of nine public universities in Wroclaw, Poland.A representative quota sample of 370 (2,78%) out of 102160 students of nine public universities participated in the face-toface structured interview using the polish version of WMH-CIDI 3.0.Estimated lifetime prevalence of serious suicidal thoughts is 9,19%. Those thoughts occur for the first time on average at the age of 16,4. Serious plans of committing suicide were reported by 3,24% of all students who participated in the study.Moreover 1,35% admitted planning suicide in 12 months prior to the interview. The average age in which such ideations occur for the first time is 15,5 years old. Lifetime revalence of suicide attempt is 1,62%. One third of respondents who have ever try to kill themselves made such an attempt within a year before being interviewed.Percentage gf students experiencing serious suicidal thoughts I slightly higher than in the general sample CIDI studies in Europe. Suicidal symptoms occur early in lifetime. Therefore prevention campaigns aimed in reaching those who are suicidal for the first time, should be addressed to high schools students. High percentage of 12 months suicide attempts prevalence among those who tried to kill themselves indicates need of prevention directed for university students.
900 – Cortical Surface Area Correlates Of Ston2 Gene Ser307pro Polymorphism In Patients With Schizophrenia And Healthy Controls
Authors: Bo X. 
Published: July 2013

BackgroundPrevious evidence shows that STON2 was associated with synaptic function and schizophrenia. The aim of this study is to explore the relationship STON2Ser307Pro, Ala851Ser and cortical surface area in schizophrenia patients and healthy volunteers.MethodsMRI whole cortical surface area which was computed by an automated surface-based technique (FreeSurfer) and genotypes were obtained from 74 individuals with first-episode schizophrenia and 55 controls. Multiple regressions analysis was performed using genotype subgroups to effect on cortical surface area.ResultsThere was significant genotype-by-diagnosis effect on cortical surface area, Pro-allele-carriers having larger right inferior temporal surface area in schizophrenia patients, but there was no significant on the same area in healthy volunteers, have not detected that Ala851Ser was associati[on with cortical surface area in our subjects.ConclusionThese data demonstrate that STON2 gene may be alter cortical asymmetry on the right inferior temporal, and that abnormal gene may be a core role that contributes to the pathogenesis of schizophrenia.
902 – A Combined Fmri And Vbm Study To Show Motor Deficits In Schizophrenic Versus Control Subjects During a Simple Motor Task
Authors: Singh S. , Goyal S. , Modi S. , Kumar P. , Singh N. , Bhatia T. , Deshpande S. , Khushu S. 
Published: July 2013

Schizophrenia is one of the psychotic mental disorders, characterized by social problems and disorders of thought, behaviour, motor and cognitive functions such as long-term memory, verbal memory, executive functioning and vigilance etc. However, the relation between structural and functional alterations in schizophrenia remains unclear. Therefore, the present study sought to investigate whether functional alterations in schizophrenia are also associated with structural brain aberrations directly in related brain regions or in anatomically closely connected areas.The current study was conducted to investigate the possible relationship between functional and structural changes for a simple motor task in schizophrenics.16 controls and 16 schizophrenic patients were chosen for the study. The structural and functional MRI scans were acquired using 3 Tesla whole-body MRI system with a 16 channel head array coil. For fMRI, a block paradigm with alternating blocks of motor task (right finger tapping; 120 taps/min) and rest was carried out. Pre-processing and post-processing of MRI scans were performed using SPM8 software.The fMRI study showed relatively less activation in the left precentral and postcentral gyrus and right cerebellum in schizophrenic patients as compared to controls during finger tapping task. Voxel-based morphometry (VBM) revealed grey matter decreases in the left precentral and postcentral gyrus and left middle frontal gyrus while white matter decreases in the right cerebellum and right inferior temporal gyrus of schizophrenics as compared to controls.The present study provides strong evidence for an association between motor functional deficits and structural alterations in schizophrenic patients as compared to controls.
906 – Hyponatremia And Antidepressants: Are They Worth Their Salt? a Class-per-class Review Of The Literature
Authors: De Picker L. , Van Den Eede F. , Sabbe B.G.C. 
Published: July 2013

IntroductionHyponatremia due to antidepressant-induced SIADH can cause significant morbidity and serious complications. It is commonly associated with SSRIs, but the frequency and class-specificity are unclear.ObjectivesTo determine the relationship between hyponatremia and antidepressants, defining incidence and odds ratios for antidepressant classes, along with patient risk factors.MethodsA review of the literature was performed in Web of Science and Pubmed until April 2012, using combinations of search strings “antidepressants” and antidepressant class and generic drug names with “hyponatr(a)emia”, “SIADH” or “inappropriate antidiuretic hormone secretion”.Results19 effect studies and over 50 case reports were considered, the majority concerning SSRIs. Variation in study design, population and cut-off values caused divergence of hyponatremia incidences of 0.06-40% for SSRIs and 0.08-70% for venlafaxine. Incidence numbers for mirtazapine and TCAs were tenfold lower. Odds ratios for SSRIs (1.5 -4.0) were consistently higher than for TCAs (1.1-1.9). The risk associated with MAO-inhibitors, reboxetine and bupropion could not be established due to insufficient information. Patient risk factors included older age (OR 6.3) and concommitant use of (thiazide) diuretics (OR 11.2-13.5).ConclusionHyponatremia is an underdiagnosed and potentially dangerous side-effect of antidepressants and this risk is not exclusive to SSRIs. Current evidence suggests a relatively high risk for hyponatremia with the use of SSRIs or venlafaxine, especially combined with patient risk factors, in which cases clinicians should actively screen for this complication. Mirtazapine and TCAs entail a moderate risk and can be considered as alternative treatment for patients with increased risk or history of hyponatremia.
907 – Barriers To Self Care, Illness Perceptions And Their Relationship With Self Care In Type 2 Diabetes Mellitus
Authors: Abraham A.M. , Sudhir P.M. , Bantwal G. 
Published: July 2013

IntroductionType 2 Diabetes mellitus (T2DM) is a chronic disease that requires long-term medical care and lifestyle change. Many patients find it challenging to implement required behaviour changes and consequently, do not achieve glycaemic control. It is essential to research social cognitive factors that impact self care in T2DM.AimsTo study the impact of barriers and illness perceptions on self care in T2DMObjectivesTo explore barriers to self care and illness perception and examine their relationship with self care, metabolic control and quality of life in T2DM.MethodsA cross-sectional design was employed. The sample consisted of 60 patients with type 2 DM, meeting specified inclusion and exclusion criteria, recruited from the out-patient services of a hospital at Bangalore. The Barriers of self care questionnaire (Glasgow, 1994), The Revised Illness Perception Questionnaire (Morris et. al, 2002), The Summary of Diabetes Self Care Activities (Toobert & Glasgow, 1994) and The Diabetes Quality of Life Questionnaire Brief Clinical Inventory (Burroughs, Desikan, Waterman, Gilin & McGill, 2004) were administered. Metabolic control was assessed using glycosylated haemoglobin levels (HbA1c).ResultsFindings revealed that barriers to self care, negative perceptions of consequences of the illness and negative emotional representations were associated with poorer self care. Adherence was associated with better metabolic control and quality of life.ConclusionsBarriers to self care and maladaptive illness representations pose a challenge in achieving self-care goals. Understanding barriers is the first step in facilitating practitioners to identify their role in enabling patients to overcome them.
912 – The Impacts Of Fear Of Crime On The Mental Health And Avoidance Behaviors Of Older Chinese
Authors: Qin N. , Yan E. 
Published: July 2013

IntroductionFear of crime is a kind of unpleasant and often intense emotion caused by perceived risk of being victimized. It is evidenced that fear of crime has tremendous impacts on the mental health of older people who resort to avoidance behaviors for self-protection.ObjectivesThis study examined the impact of fear of crime on the mental health and avoidance behavior of the communitydwelling older adults living in urban China.MethodsFor the present study, data were collected from a representative sample of 453 older persons aged 60 years and above from Kunming, Yunnan province using face-to-face interview. Associations between fear of crime and mental health, and avoidance behavior were measured using linear regression.ResultsThe final sample ranged from 60 to 100 years of age (Mean = 72.29, SD = 8.27) and included 198 (43.7%) males and 255 females. Preliminary results showed that 258 participants (57.0%) reported fear of one or more types of depicted crimes; 397 (87.6%) carried on one or more kinds of avoidance behaviors; and 234 (51.7%) presented deteriorating mental health. Results of hierarchical regression analyses indicated that fear of crime was a significant predictor of both poorer mental health (p < .05) and more avoidance behaviors (p < .001), independent of gender, age, education, household finance, length of residence in neighborhood, household size, living arrangement, physical health and social networks.ConclusionsFear of crime had detrimental impacts on mental health of older Chinese and resulted in reduced social participation due to their avoidance behaviors.
921 – Physical Health Monitoring Of Patients Taking Antipsychotic Medication In Primary And Secondary Care: a Complete Audit
Authors: Jesudason P. , Narayan V. 
Published: July 2013

IntroductionMortality due to physical illness is greater in schizophrenia than in the general population. Antipsychotics have been linked with weight gain, diabetes and hyperlipidaemia. UK guidelines recommend annual health screens in primary care, and secondary care ensure patients receive this and document results in notes.ObjectivesTo establish whether patients taking antipsychotics received annual monitoring of U&E, FBC, Lipids, Glucose, LFT, weight and blood pressure. Standards for the audit were derived from the Maudsley Prescribing Guidelines and NICE Guidelines on Schizophrenia.AimsTo improve physical health monitoring for our patients.MethodsWe retrospectively reviewed 82 case notes. Intervention following initial audit included education of professionals involved in monitoring and inclusion of a Prescribed Medication Monitoring Form in case notes. Re-audit occurred 12 months after initial audit. Statistical analysis used χ2-test with Yates’ Continuity Correction.ResultsFollowing intervention recommendation of physical health monitoring to primary care increased from 40.2% to 76.8% (P < 0.0001), as did monitoring frequency: Weight (7.3% to 54.3%), BP (7.3% to 49.4%), U&E (64.6% to 82.5%), FBC (61.0% to 78.5%,) Lipids (47.6% to 72.2%), Glucose (59.8% to 79.7%) and LFT (61.0% to 81.3%) (P < 0.05 for all parameters). Documentation of blood results in secondary care notes was also increased (P < 0.05).ConclusionsMonitoring of physical health comorbidity in patients with serious mental illness was poor in the initial audit. This can be improved in both primary and secondary care by relatively simple measures and by increasing clinicians' understanding of the importance of monitoring.
929 – Principles Of Supervision In Cognitive Behavioural Therapy
Authors: Vyskocilova J. , Prasko J. 
Published: July 2013

The task of supervision is obvious - to increase the value of the therapeutic process in the client's best interest. At the same time, supervision is an educational process in the truest sense of the word, including an opportunity to select one's own supervisor. This is a very important procedural aspect since the therapist identifies with his/her supervisor, either consciously or unconsciously. Establishing the supervisor-supervisee relationship is based on principles similar to those in the therapeutic relationship. There is an important parallel reflecting the therapist-client relationship. This is because any changes in the supervisory process are analogically transferred into the therapist-client relationship. Additionally, supervision is oriented towards increasing the therapist's competencies. The CBT therapist's basic skills involve good theoretical knowledge, professional behaviour towards clients, ability to use specific therapeutic strategies for maintaining the therapeutic relationship, sensitivity to parallel processes and accomplishment of changes, and adherence to ethical norms. Given the fact that during supervision, the supervisee may be in any stage of his/her training, supervision must take into consideration where the therapist is in his/her training and development and what he/she has or has not learnt. Supervision may only lead to the supervisee's professional growth if it supports his/her individuality and helps him/her to discover things. Therefore, numerous approaches are used in supervision which are associated with the abilities to self-reflect and to realize transference and countertransference mechanisms.Supported by project IGA MZ ČR NS 10301-3/2009
935 – Cerebellar Motor Learning Deficits In Patients With Recent-onset Schizophrenia
Authors: Röder C. , Coesmans M. , Koekkoek S.K.E. , de Zeeuw C.I. , Frens M.A. , van der Geest J.N. 
Published: July 2013

IntroductionThe notion that cerebellar deficits may underlie clinical symptoms in schizophrenia is tested by evaluating two forms of cerebellar learning in recent-onset schizophrenia patients. A potential medication effect is evaluated by including patients with or without antipsychotics.MethodsSaccadic eye movement adaptation and eyeblink-conditioning were assessed in 39 male patients with recent-onset schizophrenia who were on antipsychotic medication (clozapine n=10 haloperidol n=16) or antipsychotic-free (n=13), and in 29 age-matched male control subjects.ResultsAll participants showed significant saccadic adaptation. Adaptation strength did not differ between healthy controls and schizophrenia patients. The speed of saccade-adaptation, however, was significantly lower in schizophrenia patients. Patients showed a significantly lower increase in the number of conditioned eyeblink responses (CR). Over all experiments no constistent effects of medication were observed. These outcomes did not correlate with age, duration of education, psychopathology or dose of antipsychotics.ConclusionsIn this study we find several cerebellar learning deficits in patients with schizophrenia that we cannot attribute to the use of antipsychotics. Although this finding, combined with the fact that deficits are already present in recent-onset schizophrenia, could suggest that cerebellar impairments are a trait deficit in schizophrenia, this should be confirmed in longitudinal studies.
943 – Mental Disorders In Rheumatoid Arthritis Patients: Stress Factors And Pain Relations
Authors: Veltishchev D. , Lisitsyna T. , Kovalevskaya O. , Seravina O. , Zeltyn A. , Krasnov V. , Nasonov E. 
Published: July 2013

ObjectiveTo analyze the prevalence of stress factors, mental disorders (MD) and their influence on pain in rheumatoid arthritis (RA) patients (pts).Methods125 RA-pts with a mean age of 47.4±1.01 yrs and disease duration of 138.4±10.1 month were enrolled. The RA disease activity was assessed by DAS-28. BPI was used for pain severity assessment. MD were diagnosed in accordance with ICD-10 criteria.ResultsMD were diagnosed in 117 (93.6%) RA pts: depressive episode (n=46,39%) (RDD incl. - 27%); dysthymia (n=41,35%), adjustmend disorders(n=21,18%); GAD (n=9,8%). Mild cognitive disorder was diagnosed in 83 (66.4%) of RA-pts. The significant stress factors preceding RA manifestation were found in 97 (77.6%) cases; in 76 (61%) - stress factors preceded RA exacerbation. Significant chronic stress events during childhood had 84 (67.2%) patients. Patients with MD more often (p< 0.05) had the fourth X-ray stage of RA and maximal stage of functional disability. Mean age of the first prednisone intake was significantly higher (p< 0.05) in patients with MD. RA-pts with severe pain (=7 BPI-points) were 3 times more likely to have depressive disorder than RA-pts with mild pain (1-4 BPI-point) (48.6% vs 15.6%, ?R=3.1, 95% CI=0.97-9.93, ?=0.004).ConclusionThe results have shown high prevalence of stress related MD in RA-pts and confirm the stress-diathesis approach to pathogenesis of MD in rheumatic disease. The RA patients group with MD had high level of pain severity, X-ray stage and functional disability in comparison with patients without MD.