bluuebunny/crossref_metadata_2025_split huggingface dataset:
Social affordances: Is the mirror neuron system involved?
Authors: Dezecache Guillaume , Conty Laurence , Grèzes Julie 
Published: July 2013

AbstractWe question the idea that the mirror neuron system is the substrate of social affordances perception, and we suggest that most of the activity seen in the parietal and premotor cortex of the human brain is independent of mirroring activity as characterized in macaques, but rather reflects a process of one's own action specification in response to social signals.
From synthetic modeling of social interaction to dynamic theories of brain–body–environment–body–brain systems
Authors: Froese Tom , Iizuka Hiroyuki , Ikegami Takashi 
Published: July 2013

AbstractSynthetic approaches to social interaction support the development of a second-person neuroscience. Agent-based models and psychological experiments can be related in a mutually informing manner. Models have the advantage of making the nonlinear brain–body–environment–body–brain system as a whole accessible to analysis by dynamical systems theory. We highlight some general principles of how social interaction can partially constitute an individual's behavior.
A mature second-person neuroscience needs a first-person (plural) developmental foundation
Authors: Lewis Charlie , Stack James 
Published: July 2013

AbstractSchilbach et al.'s model assumes that the ability to “experience” minds is already present in human infants and therefore falls foul of the very intellectualist problems it attempts to avoid. We propose an alternative relational, action-based account, which attempts to grasp how the individual's construction of knowledge develops within interactions.
A second-person approach cannot explain intentionality in social understanding
Authors: Moore Chris , Paulus Markus 
Published: July 2013

AbstractA second-person approach that prioritizes dyadic emotional interaction is not well equipped to explain the origins of the understanding of mind conceived as intentionality. Instead, the critical elements that will deliver the understanding of self and other as persons with intentionality are shared object-centered interactions that include not only emotional engagement, but also joint attention and joint goal-directed action.
Ways of crossing a spatial boundary in typologically distinct languages
Authors: ÖZÇALIŞKAN ŞEYDA 
Published: July 2013

ABSTRACTExpression of spatial motion shows wide variation as well as patterned regularities across the world's languages (Talmy, 2000), and events involving the traversal of a spatial boundary impose the tightest typological constraints in the lexicalization of motion, providing a true test of cross-linguistic differences. Speakers of verb-framed languages are required by their languagenotto use manner verbs in marking the change of location across boundaries (Aske, 1989). Here we test the strength of the boundary-crossing constraint and ask how speakers convey motion events when the constraints imposed by the experimental task are at odds with the constraints imposed by their native language. We address this question by comparing adult speakers’ description of motion scenes that involve the traversal of a spatial boundary in two typologically distinct languages: English and Turkish. Using an experimental paradigm that imposes competing demands with the semantic structure of Turkish, we compare Turkish speakers’ description of boundary-crossing scenes to that of English speakers. We find strong cross-linguistic differences in speakers’ verb choice (manner vs. path) and event segmentation (one vs. many), suggesting that boundary-crossing constraint can serve as a reliable test to detect the typological class of a language.
Does argument structure complexity affect reading? A case study of an Italian agrammatic patient with deep dyslexia
Authors: BARBIERI ELENA , AGGUJARO SILVIA , MOLTENI FRANCO , LUZZATTI CLAUDIO 
Published: July 2013

ABSTRACTThe argument structure complexity hypothesis (Thompson, 2003) was introduced to account for the verb production pattern of agrammatic patients, who show greater difficulty in producing transitive versus unergative verbs (argument number effect) and in producing unaccusative versus unergative verbs (syntactic movement effect). The present study investigates these two effects in the reading performance of a patient (GR) suffering from deep dyslexia. GR read nouns significantly better than verbs; moreover, her performance was better on unergative than on transitive verbs, whereas the comparison between unergative and unaccusative verbs did not differ significantly. Data support the extension of the argument structure complexity hypothesis to word naming and suggest that the two aspects of argument structure complexity occur at different levels within models of lexical processing.
Nouns to verbs and verbs to nouns: When do children acquire class extension rules for deverbal nouns and denominal verbs?
Authors: LIPPEVELD MARIE , OSHIMA-TAKANE YURIKO 
Published: July 2013

ABSTRACTWe investigated when children acquire class extension rules for denominal verbs and deverbal nouns using an intermodal preferential looking paradigm. We taught French-speaking 2.5-year-olds (mean age = 2 years, 8.56 months [2;8.56], range = 2;6–2;11) and 3-year-olds (mean age = 3;3.31, range = 3;0–3;5) novel parent nouns or verbs referring to unfamiliar instruments and their functions, and then tested their interpretation of both the parent word and its denominal verb or deverbal noun. Experiment 1 demonstrated that only the 3-year-olds understood the denominal verbs. Experiment 2 demonstrated that only 3-year-olds who learned the parent verbs were able to interpret the deverbal nouns correctly. These findings suggest that French-speaking children acquire class extension rules for denominal verbs and deverbal nouns by the age of 3 years and can demonstrate this knowledge as long as they are able to learn the parent words.
Given–new/new–given? Children's sensitivity to the ordering of information in complex sentences
Authors: JUNGE BIANCA , THEAKSTON ANNA L. , LIEVEN ELENA V. M. 
Published: July 2013

ABSTRACTEnglish and many other languages allow flexible ordering of main and subordinate clauses in complex sentences. Processing, discourse-pragmatics, and semantics have an impact on the ordering of information. Three-year-olds, 5-year-olds, and adults heard complex sentences containing main and subordinate clauses with differing informational status. Using an act-out method, we analyzed participants’ sensitivity to the ordering of new/given information and its interaction with clause order. All age groups changed the order of information to given–new when exposed to a new–given structure, whereas only adults changed the clause order to subordinate–main when exposed to the reverse. We suggest that children are sensitive to information structure but not clause order in complex sentences. The results are discussed in the context of possible limited processing capacities or understanding of clause order function in complex sentences.
An Evolving Scientific Public Sphere: State Science Enlightenment, Communicative Discourse, and Public Culture from Imperial Russia to Khrushchev's Soviet Times
Authors: Andrews James T. 
Published: July 2013

ArgumentBy the late nineteenth century, science pedagogues and academicians became involved in a vast movement to popularize science throughout the Russian empire. With the aftermath of the 1917 Bolshevik Revolution, many now found the new Marxist state a willing supporter of their goals of spreading science to an under-educated public. In the Stalin era, Soviet state officials believed that the spread of science and technology had to coalesce with the Communist Party's utilitarian goals and needs to revive the industrial sector of the economy. This resulted in a new Stalinist technologically oriented popularization campaign. In the Khrushchev era (1953–64), Soviet politicians became increasingly more aware of the competitive power of Soviet technology in the global arena and developed extensive campaigns to publicize Soviet feats for a broad domestic and foreign public audience. This was particularly true for topics such as the space program and big technologies such as nuclear power.
From Papers to Newspapers: Miguel Masriera (1901–1981) and the Role of Science Popularization under the Franco Regime
Authors: Nieto-Galan Agustí 
Published: July 2013

ArgumentThis paper analyzes the political dimension of Miguel Masriera's (1901–1981) science popularization program. In the 1920s, Masriera worked at the Swiss Federal Institute of Technology (ETH) in Zurich – with Hermann Staudinger, the luminary of polymer chemistry – to later become a lecturer of theoretical and physical chemistry at the University of Barcelona. After living in exile in Paris, at the end of the Civil War he returned to Spain but never recovered his position. Instead, Masriera became an active popular science writer and adapted to the severe constraints of General Franco's military dictatorship (1939–1975). Inspired by the astronomer Arthur Eddington's world view, Masriera wrote and translated popular science books, and published articles in daily newspapers and journals. By examining Masriera's popular works, in particular his program for spreading “atomic culture” in Spain during the Cold War, this paper aims to contribute to the assessment of the role of science popularization in the domestic legitimization of that dictatorial regime and also its use as a vehicle for international recognition abroad.
Counting Plane Graphs: Cross-Graph Charging Schemes
Authors: SHARIR MICHA , SHEFFER ADAM 
Published: July 2013

We study cross-graph charging schemes for graphs drawn in the plane. These are charging schemes where charge is moved across vertices of different graphs. Such methods have recently been used to obtain various properties of triangulations that are embedded in a fixed set of points in the plane. We generalize this method to obtain results for various other types of graphs that are embedded in the plane. Specifically, we obtain a new bound ofO*(187.53N) (where theO*(⋅) notation hides polynomial factors) for the maximum number of crossing-free straight-edge graphs that can be embedded in any specific set ofNpoints in the plane (improving upon the previous best upper bound 207.85Nin Hoffmann, Schulz, Sharir, Sheffer, Tóth and Welzl [14]). We also derive upper bounds for numbers of several other types of plane graphs (such as connected and bi-connected plane graphs), and obtain various bounds on the expected vertex-degrees in graphs that are uniformly chosen from the set of all crossing-free straight-edge graphs that can be embedded in a specific point set.We then apply the cross-graph charging-scheme method to graphs that allow certain types of crossings. Specifically, we consider graphs with no set ofkpairwise crossing edges (more commonly known ask-quasi-planar graphs). Fork=3 andk=4, we prove that, for any setSofNpoints in the plane, the number of graphs that have a straight-edgek-quasi-planar embedding overSis only exponential inN.
Predictors of Neurobehavioral Symptoms in a University Population: A Multivariate Approach Using a Postconcussive Symptom Questionnaire
Authors: Ettenhofer Mark L. , Reinhardt Lindsay E. , Barry David M. 
Published: July 2013

AbstractSeveral factors have been linked to severity of postconcussive-type (neurobehavioral) symptoms. In this study, predictors of neurobehavioral symptoms were examined using multivariate methods to determine the relative importance of each. Data regarding demographics, symptoms, current alcohol use, history of traumatic brain injury (TBI), orthopedic injuries, and psychiatric/developmental diagnoses were collected via questionnaire from 3027 university students. The most prominent predictors of symptoms were gender, history of depression or anxiety, history of attention-deficit/hyperactivity disorder or learning disability diagnosis, and frequency of alcohol use. Prior mild TBI was significantly related to overall symptoms, but this effect was small in comparison to other predictors. These results provide further evidence that neurobehavioral symptoms are multi-determined phenomena, and highlight the importance of psychiatric comorbidity, demographic factors, and health behaviors to neurobehavioral symptom presentation after mild TBI. (JINS, 2013, 19, 1–9)
GRP78-targeting subtilase cytotoxin sensitizes cancer cells to photodynamic therapy
Authors: Firczuk M , Gabrysiak M , Barankiewicz J , Domagala A , Nowis D , Kujawa M , Jankowska-Steifer E , Wachowska M , Glodkowska-Mrowka E , Korsak B , Winiarska M , Golab J 
Published: July 2013

AbstractGlucose-regulated protein 78 (GRP78) is an endoplasmic reticulum (ER)-resident chaperone and a major regulator of the unfolded protein response (UPR). Accumulating evidence indicate that GRP78 is overexpressed in many cancer cell lines, and contributes to the invasion and metastasis in many human tumors. Besides, GRP78 upregulation is detected in response to different ER stress-inducing anticancer therapies, including photodynamic therapy (PDT). This study demonstrates that GRP78 mRNA and protein levels are elevated in response to PDT in various cancer cell lines. Stable overexpression of GRP78 confers resistance to PDT substantiating its cytoprotective role. Moreover, GRP78-targeting subtilase cytotoxin catalytic subunit fused with epidermal growth factor (EGF-SubA) sensitizes various cancer cells to Photofrin-mediated PDT. The combination treatment is cytotoxic to apoptosis-competent SW-900 lung cancer cells, as well as to Bax-deficient and apoptosis-resistant DU-145 prostate cancer cells. In these cells, PDT and EGF-SubA cytotoxin induce protein kinase R-like ER kinase and inositol-requiring enzyme 1 branches of UPR and also increase the level of C/EBP (CCAAT/enhancer-binding protein) homologous protein, an ER stress-associated apoptosis-promoting transcription factor. Although some apoptotic events such as disruption of mitochondrial membrane and caspase activation are detected after PDT, there is no phosphatidylserine plasma membrane externalization or DNA fragmentation, suggesting that in DU-145 cells the late apoptotic events are missing. Moreover, in SW-900 cells, EGF-SubA cytotoxin potentiates PDT-mediated cell death but attenuates PDT-induced apoptosis. In addition, the cell death cannot be reversed by caspase inhibitor z-VAD, confirming that apoptosis is not a major cell death mode triggered by the combination therapy. Moreover, no typical features of necrotic or autophagic cell death are recognized. Instead, an extensive cellular vacuolation of ER origin is observed. Altogether, these findings indicate that PDT and GRP78-targeting cytotoxin treatment can efficiently kill cancer cells independent on their apoptotic competence and triggers an atypical, non-apoptotic cell death.
Dynamics of a vertical cavity quantum cascade phonon laser structure
Authors: Maryam W. , Akimov A. V. , Campion R. P. , Kent A. J. 
Published: July 2013

AbstractDriven primarily by scientific curiosity, but also by the potential applications of intense sources of coherent sound, researchers have targeted the phonon laser (saser) since the invention of the optical laser over 50 years ago. Here we fabricate a vertical cavity structure designed to operate as a saser oscillator device at a frequency of 325 GHz. It is based on a semiconductor superlattice gain medium, inside a multimode cavity between two acoustic Bragg reflectors. We measure the acoustic output of the device as a function of time after applying electrical pumping. The emission builds in intensity reaching a steady state on a timescale of order 0.1 μs. We show that the results are consistent with a model of the dynamics of a saser cavity exactly analogous to the models used for describing laser dynamics. We also obtain estimates for the gain coefficient, steady-state acoustic power output and efficiency of the device.
Relationship between urinary sodium excretion and serum aldosterone in patients with diabetes in the presence and absence of modifiers of the renin–angiotensin–aldosterone system
Authors: Libianto Renata , Jerums George , Lam Que , Chen Angela , Baqar Sara , Pyrlis Felicity , Macisaac Richard J. , Moran John , Ekinci Elif I. 
Published: July 2013

Although low dietary salt intake has beneficial effects on BP (blood pressure), low 24hUNa (24 h urinary sodium excretion), the most accurate estimate of dietary salt intake, is associated with increased mortality in people with diabetes. In the non-diabetic population, low salt intake is associated with increased RAAS (renin–angiotensin–aldosterone system) activity. In this cross-sectional study, we examined the relationship between 24hUNa, PRA (plasma renin activity), serum aldosterone and BNP (brain natriuretic peptide) in patients with diabetes. Clinical characteristics, 24hUNa, PRA, serum aldosterone and BNP were recorded in 222 consecutive patients (77% with Type 2 diabetes) attending a diabetes clinic at a tertiary hospital. The relationship between 24hUNa, serum aldosterone, PRA, BNP, urinary potassium excretion, serum potassium, serum sodium, eGFR (estimated glomerular filtration rate), urinary albumin excretion and HbA1c (glycated haemoglobin) was examined by a multivariable regression model. Levels of 24hUNa significantly predicted serum aldosterone in a linear fashion (R2=0.20, P=0.002). In the subgroup of patients (n=46) not taking RAAS-modifying agents, this relationship was also observed (R2=0.10, P=0.03), and the effect of 24hUNa on serum aldosterone was found to be more pronounced than in the whole cohort (coefficient=−0.0014, compared with −0.0008). There was no demonstrable relationship between 24hUNa and PRA or BNP. Low 24hUNa is associated with increased serum aldosterone in people with diabetes, in the presence and absence of RAAS-modifying agents. This raises the possibility that stimulation of the RAAS may be a mechanism that contributes to adverse outcomes observed in patients with low 24hUNa.
Prevalence and Predictors of Compliance with Discontinuation of Airborne Isolation in Patients with Suspected Pulmonary Tuberculosis
Authors: Thomas Benjamin S. , Bello Erlaine F. , Seto Todd B. 
Published: July 2013

Objective.Examine the use of airborne isolation by identifying reasons for nontimely discontinuation and predictors of compliance with Centers for Disease Control and Prevention (CDC) guidelines. Compliance with guidelines should result in timely (within 48 hours) discontinuation of isolation in patients without infectious pulmonary tuberculosis (TB).Design.Retrospective, observational study.Setting.A private, university-affiliated, tertiary-care medical center.Patients.All patients in airborne isolation for suspected pulmonary TB from June through December 2011.Method.Chart reviews were performed to identify airborne isolation practices and delayed (greater than 48 hours) or very delayed (greater than 72 hours) discontinuation. We used descriptive statistics and logistic regression to determine independent predictors of nontimely discontinuation of isolation.Results.We identified 113 patients (mean age ± standard deviation, 59.8 ± 17.7 years; male sex, 75.2%; white race, 15.9%; mean collection interval ± standard deviation, 21.4 ± 12.9 hours). Delayed and very delayed isolation discontinuation was noted in 81% and 49% of patients, respectively. No significant differences in demographic characteristics and clinical characteristics were identified between groups. Predictors of timely (within 48 hours) airborne isolation discontinuation included use of alternate diagnosis for discontinuation of isolation (P = .02), early infectious diseases (ID) consultation (P = .03), pulmonary consultation (P = .02), average sputum collection interval less than 24 hours (P = .03), and need for more than 1 induced sputum specimen (P = .05). Adjusting for potential confounders, pulmonary consultation (odds ratio [OR] [95% confidence interval (CI)], 0.14 [0.03-0.58]), alternate diagnosis for discontinuation of isolation (OR [95% CI], 4.5 [1.3-15.8]), and early ID consultation (OR [95% CI], 4.0 [1.1-14.8]) were independently associated with timely discontinuation.Conclusions.Timely airborne isolation discontinuation occurs in only 18.6% of cases and is an opportunity for cost savings, improved efficiency, and potentially patient safety and satisfaction.
Secular Trends in Gram-Negative Resistance among Urinary Tract Infection Hospitalizations in the United States, 2000–2009
Authors: Zilberberg Marya D. , Shorr Andrew F. 
Published: July 2013

Objective.Urinary tract infections (UTIs) are common among hospitalized patients. Selection of an appropriate antibiotic for this infection requires knowledge of both its general microbiology and the epidemiology of drug-resistant organisms. We sought to determine secular trends in UTI hospitalizations that involve gram-negative (GN) multidrug-resistant Pseudomonas aeruginosa (MDR-PA), extended-spectrum β-lactamase (ESBL)-producing Escherichia coli (EC) and Klebsiella pneumoniae(KP), and carbapenem-resistant Enterobacteriaceae (CRE).Design.Survey.Patients.Patients with UTI in US hospitals between 2000 and 2009.Methods.We first derived the total number of UTI hospitalizations in the United States from the Healthcare Cost and Utilization Project Nationwide Inpatient Sample database years 2000–2009. Based on a literature review, we then determined what proportion of all UTIs arise due to each of the organisms of interest, irrespective of resistance pattern. Finally, we assessed the prevalence of resistance within each pathogen based on the Eurofins Surveillance Network database 2000–2009. Susceptibility patterns served as phenotypic surrogates for resistance.Results.Between 2000 and 2009, the frequency of UTI hospitalizations increased by approximately 50%, from 53 to 77 cases per 1,000 hospitalizations. Infections due to all GN bacteria followed a similar trajectory, whereas those caused by resistant GN pathogens increased by approximately 50% (MDR-PA) to approximately 300% (ESBL). CRE emerged and reached 0.5 cases per 1,000 hospitalizations in this 10-year period.Conclusions.The epidemiology and microbiology of GN UTI hospitalizations has shifted over the past decade. The proportion of all hospitalizations involving this infection has climbed. Resistant GN bacteria are becoming more prevalent and are implicated in an increasing proportion of UTIs among hospitalized patients.
Thinking Equality Today: Badiou, Rancière, Nancy
Authors: Watkin Christopher 
Published: July 2013

Abstract
Recent work on Alain Badiou and Jacques Rancière has rightly identified equality both as a central theme in their own thinking and as the key notion in contemporary radical political thought more broadly, but a focus on the differences between their respective accounts of equality has failed to clarify a major problem that they share. The problem is that human equality is said to rest on a particular human capacity, leaving Badiou's axiomatic equality and Rancière's assumed equality vulnerable to the charge of having a blind spot for some of society's most vulnerable. This article introduces an alternative understanding of equality drawn from the thought of Jean-Luc Nancy, an equality that does not rely on a human capacity to guarantee or verify it but rests on Nancy's notion of sense. The article explores the advantages of Nancy's account of equality in relation to sense over and against an alternative reading that focuses on Nancy's evocation of the suffering human body, before addressing, in conclusion, the problems with which Nancy's idea of equality will have to grapple, and why, despite these problems, it is still preferable to the Badiouian and Rancièrian approaches.