bluuebunny/crossref_metadata_2025_split huggingface dataset:
Service quality in an Australian private dental network
Authors: Edward Baldwin Alan 
Published: May 2014

Purpose
– This longitudinal research project seeks to monitor and report on the levels of patient satisfaction with the delivery of dental care provided by the Australian Unity Dental Centres (AUDC), which offer private dental care to people within Australia. The purpose of this paper is to discuss the above issue.

Design/methodology/approach
– The primary data gathering medium employed in this research was a survey based upon the SERVQUAL instrument. The research compares results obtained from the initial 2000 survey with the results of surveys conducted through to 2012. The key question addressed in this report is: how have patient perceptions of the service quality of care received at AUDC changed between the 2000 and 2012 survey periods?

Findings
– The level of expected service has improved over the study period, as has the level of perceived service delivered. A number of areas that would benefit from further improvement are identified and matched to specific actions that are being implemented by the business.

Practical implications
– A principal objective of the AUDC is to provide high-quality dental care to the patients. This objective can be best pursued through a regime that recognises that high-quality clinical outcomes are often dependent upon patients following recommended treatment pathways. This dependency pre-supposes that patients understand the treatment pathway's compliance requirements and, further, agree to comply with them.

Originality/value
– No other research projects have utilised eight iterations of SERVQUAL over a 13-year period in the dental service delivery sector.
Enterprise self-assessment analytics for sustainability, resilience and robustness
Authors: Edgeman Rick , A. Williams Joseph 
Published: May 2014

Purpose
– The purpose of this paper is to integrate resilience, robustness, and resplendence (R
3) with sustainable enterprise excellence (SEE) and social-ecological innovation (SEI) that assist firms to progress toward continuously relevant performance proceeding from continuously responsible strategy, behavior, and other actions.

Design/methodology/approach
– Sustainable enterprise excellence, resilience, robustness, and resplendence (SEER3) model and the associated means of SEER
3 maturity assessment are introduced to explain the organizational concept.

Findings
– SEER3 balances the complementary and competing interests of key stakeholder segments, including society and the natural environment and increases the likelihood of superior and sustainable competitive positioning and hence long-term enterprise success that is defined by continuously relevant and responsible governance, strategy, actions, and performance consistent with high-level organizational R3.

Originality/value
– This paper adapts the established principles from physics to characterize enterprise R3 to come up with SEE model.
Healthy and unhealthy food in Italian television ads for adults and children
Authors: Romana Puggelli Francesca , Bertolotti Mauro 
Published: May 2014

Purpose
– The aim of the research is to investigate how healthy and unhealthy foods (e.g., those of little nutritional value, but high fat and sugar content) are represented in televised advertising, analyzing the differences in persuasive strategies used to promote them.

Design/methodology/approach
– Content analysis was performed on 62 food advertisings broadcast on the main Italian national TV channels, focusing on target, representation of food consumption, number and gender of the main characters, visual and sound effects (i.e. music jungles etc.) and references to nutritional properties.

Findings
– Results showed that healthy food products are marketed almost exclusively to adults, using adult-oriented advertising techniques, whereas unhealthy food advertisings rely on communicative formats and appeals more suited for children and adolescents.

Originality/value
– The research first investigated, with a simple descriptive approach, how television advertising of unhealthy food products relies on specifically crafted communication in order to attract young consumers' attention and, ultimately, affect their buying intentions.
Elucidation of the Burkholderia cenocepacia hopanoid biosynthesis pathway uncovers functions for conserved proteins in hopanoid‐producing bacteria
Authors: Schmerk Crystal L. , Welander Paula V. , Hamad Mohamad A. , Bain Katie L. , Bernards Mark A. , Summons Roger E. , Valvano Miguel A. 
Published: May 2014

SummaryHopanoids are bacterial surrogates of eukaryotic membrane sterols and among earth's most abundant natural products. Their molecular fossils remain in sediments spanning more than a billion years. However, hopanoid metabolism and function are not fully understood. Burkholderia species are environmental opportunistic pathogens that produce hopanoids and also occupy diverse ecological niches. We investigated hopanoids biosynthesis in Burkholderia cenocepacia by deletion mutagenesis and structural characterization of the hopanoids produced by the mutants. The enzymes encoded by hpnH and hpnG were essential for production of all C35 extended hopanoids, including bacteriohopanetetrol (BHT), BHT glucosamine and BHT cyclitol ether. Deletion of hpnI resulted in BHT production, while ΔhpnJ produced only BHT glucosamine. Thus, HpnI is required for BHT glucosamine production while HpnJ is responsible for its conversion to the cyclitol ether. The ΔhpnH and ΔhpnG mutants could not grow under any stress condition tested, whereas ΔhpnI, ΔhpnJ and ΔhpnK displayed wild‐type growth rates when exposed to detergent, but varying levels of sensitivity to low pH and polymyxin B. This study not only elucidates the biosynthetic pathway of hopanoids in B. cenocepacia, but also uncovers a biosynthetic role for the conserved proteins HpnI, HpnJ and HpnK in other hopanoid‐producing bacteria.
Transcriptional and translational control through the 5′‐leader region of the dmpR master regulatory gene of phenol metabolism
Authors: Madhushani Anjana , del Peso‐Santos Teresa , Moreno Renata , Rojo Fernando , Shingler Victoria 
Published: May 2014

SummaryExpression of pathways for dissimilation of toxic aromatic compounds such as (methyl)phenols interfaces both stress‐response and carbon catabolite repression control cascades. In Pseudomonas putida, carbon catabolite repression is mediated by the protein Crc – a translational repressor that counteracts utilization of less‐preferred carbon sources as growth substrates until they are needed. In this work we dissect the regulatory role of the 5′‐leader region (5′‐LR) of the dmpR gene that encodes the master regulator of (methyl)phenol catabolism. Using deletion and substitution mutants combined with artificial manipulations of Crc availability in P. putida, we present evidence that a DNA motif within the 5′‐leader region is critical for inhibition of the output from the Pr promoter that drives transcription of dmpR, while the RNA chaperone Hfq facilitates Crc‐mediated translation repression through the 5′‐leader region of the dmpR mRNA. The results are discussed in the light of a model in which Hfq assists Crc to target a sequence within a loop formed by secondary structure of the 5′‐LR mRNA. Our results support the idea that Crc functions as a global translational inhibitor to co‐ordinate hierarchical carbon utilization in Pseudomonads.
A genomic island integrated into recA of Vibrio cholerae contains a divergent recA and provides multi‐pathway protection from DNA damage
Authors: Rapa Rita A. , Islam Atiqul , Monahan Leigh G. , Mutreja Ankur , Thomson Nicholas , Charles Ian G. , Stokes Harold W. , Labbate Maurizio 
Published: May 2014

SummaryLateral gene transfer (LGT) has been crucial in the evolution of the cholera pathogen, Vibrio cholerae. The two major virulence factors are present on two different mobile genetic elements, a bacteriophage containing the cholera toxin genes and a genomic island (GI) containing the intestinal adhesin genes. Non‐toxigenic V. cholerae in the aquatic environment are a major source of novel DNA that allows the pathogen to morph via LGT. In this study, we report a novel GI from a non‐toxigenic V. cholerae strain containing multiple genes involved in DNA repair including the recombination repair gene recA that is 23% divergent from the indigenous recA and genes involved in the translesion synthesis pathway. This is the first report of a GI containing the critical gene recA and the first report of a GI that targets insertion into a specific site within recA. We show that possession of the island in Escherichia coli is protective against DNA damage induced by UV‐irradiation and DNA targeting antibiotics. This study highlights the importance of genetic elements such as GIs in the evolution of V. cholerae and emphasizes the importance of environmental strains as a source of novel DNA that can influence the pathogenicity of toxigenic strains.
Modulation of primary cell function of host Pseudomonas bacteria by the conjugative plasmid pCAR1
Authors: Takahashi Yurika , Shintani Masaki , Takase Noriyuki , Kazo Yuka , Kawamura Fujio , Hara Hirofumi , Nishida Hiromi , Okada Kazunori , Yamane Hisakazu , Nojiri Hideaki 
Published: May 2014

SummaryThe impacts of plasmid carriage on the host cell were comprehensively analysed using the conjugative plasmid pCAR1 in three different Pseudomonas hosts, P. putida KT2440, P. aeruginosa PAO1 and P. fluorescens Pf0‐1. Plasmid carriage reduced host fitness, swimming motility, and resistance to osmotic or pH stress. Plasmid carriage brought about alterations in primary metabolic capacities in the TCA cycle of the hosts. Differentially transcribed genes in the three hosts associated with plasmid carriage were identified by growth phase‐dependent transcriptome analyses. Plasmid carriage commonly showed a greater effect on the host transcriptome at the transition and early stationary phases. The transcriptome alterations were similar between KT2440 and PAO1. Transcriptions of numbers of genes encoding ribosomal proteins, F‐type ATPase, and RNAP core in both strains were not suppressed enough in the early stationary phase by plasmid carriage. These responses may have been responsible for the reduction in host fitness, motility and stress resistances. Host‐specific responses to plasmid carriage were transcriptional changes of genes on putative prophage or foreign DNA regions. The extents of the impacts on host phenotypes and transcriptomes were similarly greatest in KT2440 and lowest in Pf0‐1. These findings suggest that host cell function was actively regulated by plasmid carriage.
Beyond family satisfaction: Family‐perceived involvement in residential care
Authors: Irving Justine 
Published: May 2014

AimTo explore perceived family involvement and its relationship with satisfaction and facility impressions.MethodA questionnaire was posted to residents' next of kin from four South Australian residential aged care facilities.ResultsOne hundred and fifty next of kin participated in the survey. Family‐perceived involvement was significantly and positively correlated with satisfaction and facility impressions.ConclusionThe findings of this study add to the limited body of research into family involvement in long‐term residential care. Feedback from the family regarding particular aspects of involvement may also improve the experience of long‐term care for both family and resident, and assist with the identification of specific issues towards which organisations may target their quality improvement efforts.
Accuracy of surgical wound drainage measurements: an analysis and comparison
Authors: Yue Brian , Nizzero Danielle , Zhang Chunxiao , van Zyl Natasha , Ting Jeannette 
Published: May 2014

AbstractBackgroundSurgical drain tube readings can influence the clinical management of the post‐operative patient. The accuracy of these readings has not been documented in the current literature and this experimental study aims to address this paucity.MethodsAliquots (10, 25, 40 and 90 mL) of black tea solution prepared to mimic haemoserous fluid were injected into UnoVac, RedoVac and Jackson‐Pratt drain tubes. Nursing and medical staff from a tertiary hospital were asked to estimate drain volumes by direct observation; analysis of variance was performed on the results and significance level was set at 0.05.ResultsDoctors and nurses are equally accurate in estimating drain tube volumes. Jackson‐Pratt systems were found to be the most accurate for intermediate volumes of 25 and 40 mL. For extreme of volumes (both high and low), all drainage systems were inaccurate.ConclusionThis study suggests that for intermediate volumes (25 and 40 mL), Jackson‐Pratt is the drainage system of choice. The accuracy of volume measurement is diminished at the extremes of drain volumes; emptying of drainage systems is recommended to avoid overfilling of drainage systems.
The force–velocity relationship at negative loads (assisted shortening) studied in isolated, intact muscle fibres of the frog
Authors: Edman K. A. P. 
Published: May 2014

AbstractAimThe study was undertaken to explore the force–velocity relationship under conditions where the myofilament system is subjected to an external force that serves as a negative load and assists the shortening movement.MethodsThe experiments were carried out on single muscle fibres isolated from the anterior tibialis muscle of Rana temporaria. The fibres, being operated under load‐clamp control, were released to shorten during tetanic stimulation at sarcomere lengths where the fibres carried different degrees of passive tension. The shortening thus occurred while the sarcomeres were subjected to a force that may be characterized as a ‘negative load’, that is, a force assisting the shortening movement.ResultsThe force–velocity relationship below zero load was found to be a smooth continuation of the force–velocity curve recorded at positive loads with the shortening velocity increasing steeply at loads below zero. A negative load amounting to merely 10% of the isometric force, thus raised the shortening velocity to a level two to three times higher than V0, the velocity recorded at zero load.ConclusionsThe results provide evidence that, even in the presence of a longitudinal compressive force, the speed of shortening of the muscle fibre is determined by the cycling rate of the interacting cross‐bridges. The force–velocity relationship at negative loads may play a relevant part during fast movements of striated muscle as pointed out in the discussion.
Systematic review: interactions between aspirin, and other nonsteroidal anti‐inflammatory drugs, and polymorphisms in relation to colorectal cancer
Authors: Andersen V. , Vogel U. 
Published: May 2014

SummaryBackgroundNonsteroidal anti‐inflammatory drugs (NSAIDs) include aspirin (acetylsalicylic acid, ASA). Long‐term use of NSAIDs has been associated with lowered risk of colorectal cancer (CRC), but the use is hampered by adverse effects. Also, the anti‐carcinogenic effects of NSAIDs are incompletely understood. Understanding biological effects of NSAIDs may help developing new preventive medical strategies.AimTo identify gene–environment interactions between genetic variation and NSAID use in relation to risk of CRC.MethodsWe performed a PubMed literature search and all studies reporting original data on interactions between NSAIDs and polymorphisms in relation to CRC were evaluated.ResultsWe found indications that aspirin interacted with rs6983267 close to MYC (encoding a transcription factor involved in cell cycle progression, apoptosis and cellular transformation) and NSAIDs interacted with rs3024505 and rs1800872 in or close to IL10 (encoding IL‐10) in preventing CRC. Homozygous carriers of the variant allele of rs6983267 (ca. 25% of the population) halved their risk for CRC by aspirin use compared to homozygous wildtype carriers who did not benefit from aspirin intake. No interaction between use of NSAIDs and PTGS‐2 (encoding COX‐2) in relation to CRC risk was detected. Other findings of interactions between genes in inflammatory and oncogenic pathways and NSAIDs were considered suggestive.ConclusionsKnowledge of underlying biological effects of NSAIDs in relation to CRC is scarce and the basis for stratifying the patients for preventive treatment is not yet available. Further studies assessing interactions between long‐term NSAID exposure and genetic variation in relation to CRC are warranted in large well‐characterised prospective cohorts.
Development of Clinical Pharmacology as a Medical Speciality in Europe – The Roles of WHO, IUPHAR and EACPT
Authors: Sjöqvist Folke 
Published: May 2014

AbstractThis MiniReview shows that both WHO and IUPHAR very early recognized that there is a gap between the availability of academic expert knowledge in pharmacology and its utilization in health care. Many initiatives have been taken to bridge this gap, but still 12 European countries do not recognize clinical pharmacology as a medical speciality because the profession has failed to develop defined functions in patient care. A first priority for EACPT therefore ought to be to promote clinical pharmacology as a medical speciality recognized by the European Union. The pharmacological services listed in Table 7 that focus on drug problems agree well with those that were recently prioritized in the IUPHAR/WHO/CIOMS manifesto to correct a major weakness in the health care of today in order to promote rational use of drugs.
Partially Biodegradable Distraction Implant to Replace Conventional Implants in Alveolar Bone of Insufficient Height: A Preliminary Study in Dogs
Authors: Li Tao , Zhang Yongqiang , Shao Bo , Gao Yuan , Zhang Chen , Cao Qiang , Kong Liang 
Published: May 2014

AbstractBackgroundDental implants have been widely used in the last few decades. However, patients with insufficient bone height need reconstructive surgeries before implant insertion. The distraction implant (DI) has been invented to simplify the treatment procedure, but the shortcomings of DIs have limited their clinical use. We incorporated biodegradable polyester into a novel DI called the partially biodegradable distraction implant (PBDI).PurposeThe purpose of this study was to assess the radiological, histological, and biomechanical properties of the PBDI in animal models.Material and MethodsPBDIs were manufactured and inserted into the atrophied mandibles of nine dogs. Box‐shaped alveolar bones were segmented and distracted. The dogs were randomly divided into three groups that were sacrificed 1, 2, and 3 months after the implant insertion. Actual augmentation height (AAH) of the bone segments was measured to evaluate the effect of distraction. X‐ray examination and micro‐CT reconstruction and analysis were used to evaluate the regenerated bone in the distraction gap and bone around the functional element. Histological sections were used to evaluate the osseointegration and absorption of the PBDI. Fatigue tests were used to evaluate the biomechanical properties of the PBDI.ResultsLittle change was found in AAH among the three groups. X‐ray examination and micro‐CT reconstruction showed good growth of regenerated bone in the distraction gap. Alveolar bone volume around the functional element increased steadily. No obvious bone absorption occurred in the alveolar crest around PBDI. Three months after distraction, the functional element achieved osseointegration, and the support element began to be absorbed. All PBDIs survived the fatigue test.ConclusionsThe PBDI is a novel and reliable dental implant. It becomes a conventional implant after the absorption of the support element and the removal of the distraction screw. It is a promising replacement for conventional implants in patients with insufficient alveolar bone height.
Effect of Platform Shift/Switch on Crestal Bone Levels and Mucosal Profile Following Flapless Surgery and Crestal/Subcrestal Implant Placement
Authors: Lee Jaebum , Fiorini Tiago , Gamborena Inãki , Wenzel Brent A. , Schüpbach Peter , Wikesjö Ulf M.E. , Susin Cristiano 
Published: May 2014

AbstractBackgroundCrestal remodeling/bone loss appears a common sequel to dental implant placement. Several hypotheses and clinical strategies have been advanced to explain and avert crestal remodeling; however, causative mechanisms remain unclear and the efficacy of clinical protocol uncertain.ObjectiveThe objective of the present study was to provide a histologic record of crestal versus subcrestal implant placement on crestal remodeling and mucosal profile comparing platform shift/switch and standard abutments following flapless implant surgery using a dog model.MethodsFour dental implants each were placed into the left and right edentulated posterior mandibles in five adult male hound‐Labrador mongrel dogs using a flapless approach including crestal versus subcrestal placement and using platform shift versus standard abutments. Block biopsies were collected for histological/histometric analysis following an 8‐week healing interval.ResultsBoth crestal and subcrestal implant installation resulted in significant crestal remodeling and bone loss, in particular at buccal sites, without significant differences between platform shift/switch and standard abutments. Implants installed subcrestally exhibited a significantly taller mucosal profile over crestal‐level implants without significant differences between platform shift/switch and standard abutments; the epithelial attachment at all times arrested on the abutment surface.ConclusionsComparing platform shift/switch versus standard abutments using a minimally invasive flapless approach including crestal or subcrestal implant placement, the platform shift/switch abutments offer no selective advantage over standard abutments.
The influence of sinus membrane thickness upon membrane perforation during transcrestal sinus lift procedure
Authors: Wen Shih‐Cheng , Lin Yen‐Hua , Yang Yeuh‐Chao , Wang Hom‐Lay 
Published: May 2014

AbstractObjectivesSchneiderian membrane perforation is one of the main complications during sinus augmentation. The reasons may be associated with surgical technique, septum, inadequate ridge height, and membrane thickness. However, reports that used cone‐beam computed tomography (CBCT) to quantify the thickness of sinus membrane were limited. The aims of this retrospective study were: to study the correlation between membrane thickness and perforation rate during transcrestal sinus lift and to propose a classification system of sinus membrane thickness based upon CBCT data.Material and methodsOne hundred and twenty‐two subjects who received dental implant restorations over posterior maxilla with a total of 185 transcrestal sinus lift procedures between years 2010 to 2013 were selected consequently. Each patient selected had to have taken CBCT in the initial examination and immediately after surgery. The membrane thickness, perforation rate, residual bone height, and elevated bone height were recorded and processed for statistical analysis.ResultsThe mean thickness of the Schneiderian membrane was 1.78 ± 1.99 mm. There was a significant correlation between membrane thickness and perforation rate (P < 0.05), and the perforation rate was higher in thicker (≥3 mm) and thinner membrane (≤0.5 mm). Among the thickness group, Class B (between ≥1 and <2 mm) had the lowest perforation rate. No significant difference was between the perforation and the membrane morphology. A negative relationship between residual bone height and membrane thickness was found. Trend showed that in the thicker and the thinner residual bone height, the higher the perforation rate would be.ConclusionsThere was a significant correlation between membrane thickness and perforation rate. The perforation rate was lowest when the thickness was 1.5–2 mm.