bluuebunny/crossref_metadata_2025_split huggingface dataset:
Moving research to practice through partnership: A case study in Asphalt Paving
Authors: Chang Charlotte , Nixon Laura , Baker Robin 
Published: June 2015

BackgroundMulti‐stakeholder partnerships play a critical role in dissemination and implementation in health and safety. To better document and understand construction partnerships that have successfully scaled up effective interventions to protect workers, this case study focused on the collaborative processes of the Asphalt Paving Partnership. In the 1990s, this partnership developed, evaluated, disseminated, and achieved near universal, voluntary adoption of paver engineering controls to reduce exposure to asphalt fumes.MethodsWe used in‐depth interviews (n = 15) and document review in the case study.ResultsWe describe contextual factors that both facilitated and challenged the formation of the collaboration, central themes and group processes, and research to practice (r2p) outcomes.ConclusionsThe Asphalt Paving Partnership offers insight into how multi‐stakeholder partnerships in construction can draw upon the strengths of diverse members to improve the dissemination and adoption of health and safety innovations and build a collaborative infrastructure to sustain momentum over time. Am. J. Ind. Med. 58:824–837, 2015. © 2015 Wiley Periodicals, Inc.
Hydrogel swelling properties: comparison between conventional and nanocomposite hydrogels for water shutoff treatment
Authors: Mohammadi Shabnam , Vafaie Sefti Mohsen , Baghban Salehi Mahsa , Mousavi Moghadam Asefe , Rajaee Samira , Naderi Hasan 
Published: June 2015

AbstractOne of the unique properties of hydrogels is the dramatically change in their volume and shape. In this research, conventional hydrogels (composed of sulfonated polyacrylamide and Cr(OAc)3as copolymer and crosslinker, respectively) were investigatedversusnanocomposite (NC) hydrogels for the purpose of achieving suitable composition with ability of high amount of equilibrium swelling ratio and low amount of salt sensitivity factor (f). The results showed that high ratio of Cr(OAc)3/copolymer (>0.39) and high concentration of copolymer (>27 000 ppm) were suitable areas for conventional hydrogels because of minimumffactor with still low ability of gel swelling. However, the results of NC hydrogels with composition of copolymer concentrations of 23 750 to 30 000 ppm, Cr(OAc)3/copolymer ratio of 0.28 and nano Na‐MMT concentrations of 500 to 800 ppm represented a significantly high amount of swelling and low amount offfactor. Coreflooding tests were applied to investigate the effect of polymer gel swelling in porous media for water shutoff treatment. The values of the residual resistance factor of water/oil for samples with high and low swelling ratio were 32.34 and 7.08, respectively, confirming the ability of the polymer gel with high swelling ratio in reducing the relative permeability of water/oil in porous media. © 2015 Curtin University of Technology and John Wiley & Sons, Ltd.
Is Cinderella resurging? The impact of consumers' underdog disposition on brand preferences: Underdog brand biography and brand status as moderators
Authors: Kao Danny Tengti 
Published: June 2015

AbstractThis research attempts to explore the moderating roles of underdog brand biography and brand status in the impact of consumers' underdog disposition on brand preferences. A total of 218 on‐the‐job graduate students were randomly assigned to a 2 (explicitness of underdog brand biography: implicit vs. explicit) × 2 (brand status: emerging brands vs. established brands) factorial design. Results show that consumers with strong underdog disposition are likely to generate stronger brand preferences for established brands accompanied with explicit underdog brand biographies than emerging brands accompanied with explicit underdog brand biographies; in contrast, consumers with strong underdog disposition are likely to engender no differential brand preferences for emerging brands accompanied with implicit underdog brand biographies over established brands accompanied with implicit underdog brand biographies. Moreover, consumers with a weak underdog disposition are likely to engender stronger brand preferences for established brands than emerging brands, regardless of the explicitness of underdog brand biography. Copyright © 2015 John Wiley & Sons, Ltd.
Primary cilia found on HeLa and other cancer cells
Authors: Kowal Tia J. , Falk Matthias M. 
Published: June 2015

AbstractFor many years now, researchers have known of a sensory appendage on the surface of most differentiated cell types called primary cilium. Primary cilia are both chemo‐ and mechano‐sensory in function and have an obvious role in cell cycle control. Because of this, it has been thought that primary cilia are not found on rapidly proliferating cells, for example, cancer cells. Here we report using immunofluorescent staining for the ciliary protein Arl13b that primary cilia are frequently found on HeLa (human epithelial adenocarcinoma) and other cancer cell lines such as MG63 (human osteosarcoma) commonly used for cell culture studies and that the ciliated population is significantly higher (ave. 28.6% and 46.5%, respectively in starved and 15.7–18.6% in un‐starved cells) than previously anticipated. Our finding impacts the current perception of primary cilia formed in highly proliferative cells.
CoSe2 Supported on Nitrogen‐Doped Carbon Nanohorns as a Methanol‐Tolerant Cathode for Air‐Breathing Microlaminar Flow Fuel Cells
Authors: Unni Sreekuttan M. , Mora‐Hernandez Juan M. , Kurungot Sreekumar , Alonso‐Vante Nicolas 
Published: June 2015

AbstractThe synthesis of CoSe2 nanoparticles supported on nitrogen‐doped carbon nanohorns (CoSe2/NCNH) and the influence of the interaction of the metal centre with the NCNH on the oxygen reduction reaction (ORR) are reported. CoSe2/NCNH shows a 50 mV lower onset overpotential and a 150 mV positive shift in the half‐wave potential compared to CoSe2 supported on carbon and carbon nanohorns. This suggests that the intrinsic activity and the density of active reaction centres of CoSe2 are modified by NCNHs. An air‐breathing direct methanol microlaminar flow fuel cell (μLFFC) is constructed using CoSe2/NCNH as a methanol‐tolerant cathode catalyst. A maximum power density of 10.05 mW cm−2 and a maximum current density of 124.20 mA cm−2 are achieved with CoSe2/NCNH compared to the non‐doped catalyst, CoSe2/C and Pt/C with 5 M methanol as the fuel. The improved activity of CoSe2/NCNH is attributed to the peculiar morphology and the nitrogen doping of the carbon nanohorns. This catalyst could be a suitable alternative to Pt.
Polyoxomolybdate Bisphosphonate Heterometallic Complexes: Synthesis, Structure, and Activity on a Breast Cancer Cell Line
Authors: Saad Ali , Zhu Wei , Rousseau Guillaume , Mialane Pierre , Marrot Jérôme , Haouas Mohamed , Taulelle Francis , Dessapt Rémi , Serier‐Brault Hélène , Rivière Eric , Kubo Tadahiko , Oldfield Eric , Dolbecq Anne 
Published: June 2015

AbstractSix polyoxometalates containing MnII, MnIII, or FeIII as the heteroelement were synthesized in water by treating MoVI precursors with biologically active bisphosphonates (alendronate (Ale), zoledronate (Zol), an n‐alkyl bisphosphonate (BPC9), an aminoalkyl bisphosphonate (BPC8NH2)) in the presence of additional metal ions. The Pt complex was synthesized from a polyoxomolybdate bisphosphonate precursor with MoVI ions linked by the 2‐pyridyl analogue of alendronate (AlePy). The complexes Mo4Ale2Mn, Mo4Zol2Mn, Mo4Ale2Fe, Mo4Zol2Fe, Mo4(BPC8NH2)2Fe, and Mo4(BPC9)2Fe contain two dinuclear MoVI cores bound to a central heterometallic ion. The oxidation state of manganese was determined by magnetic measurements. Complexes Mo12(AlePy)4 and Mo12(AlePy)4Pt4 were studied by solid‐state NMR spectroscopy and the photochromic properties were investigated in the solid state; both methods confirmed the complexation of Pt. Activity against the human breast adenocarcinoma cell line MCF‐7 was determined and the most potent compound was MnIII‐containing Mo4Zol2Mn (IC50≈1.3 μM). Unlike results obtained with vanadium‐containing polyoxometalate bisphosphonates, cell growth inhibition was rescued by the addition of geranylgeraniol, which reverses the effects of bisphosphonates on isoprenoid biosynthesis/protein prenylation. The results indicate an important role for both the heterometallic element and the bisphosphonate ligand in the mechanism of action of the most active compounds.
IsoCombretaQuinazolines: Potent Cytotoxic Agents with Antitubulin Activity
Authors: Soussi Mohamed Ali , Provot Olivier , Bernadat Guillaume , Bignon Jérome , Desravines Déborah , Dubois Joëlle , Brion Jean‐Daniel , Messaoudi Samir , Alami Mouad 
Published: June 2015

AbstractA series of novel isocombretaquinazolines (isoCoQ) 4 were quickly prepared by coupling N‐toluenesulfonylhydrazones with 4‐chloroquinazolines under palladium catalysis. These compounds, which can be regarded as isocombretastatin A‐4 (isoCA‐4) analogues that lack the 3,4,5‐trimethoxyphenyl ring, displayed nanomolar‐level cytotoxicity against various human cancer cell lines and were observed to effectively inhibit tubulin polymerization. The isoCoQ compounds 2‐methoxy‐5‐(1‐(2‐methylquinazolin‐4‐yl)vinyl)phenol (4 b), 4‐[1‐(3‐fluoro‐4‐methoxyphenyl)vinyl]‐2‐methylquinazoline (4 c), and 2‐methoxy‐5‐(1‐(2‐methylquinazolin‐4‐yl)vinyl)aniline (4 d), which respectively bear the greatest resemblance to isoCA‐4, isoFCA‐4, and isoNH2CA‐4, are able to arrest HCT116 cancer cells in the G2/M cell‐cycle phase at very low concentrations. Preliminary in vitro antivascular assay results show that 4 d is able to disrupt a network of capillary‐like structures formed by human umbilical vein endothelial cells on Matrigel. All these results clearly demonstrate that replacement of the 3,4,5‐trimethoxyphenyl ring of isoCA‐4 with a quinazoline nucleus is a feasible approach toward new and highly promising derivatives with the potential for further development as antitubulin agents.
Synthesis and Morphology of Two Carbazole–Pyrazoline‐Containing Polymer Systems and Their Electrical Memory Performance
Authors: Lu Cai‐jian , Li Hua , Xu Qing‐feng , Xu Qing‐hua , Lu Jian‐mei 
Published: June 2015

AbstractA new atom‐transfer radical polymerization (ATRP) initiator 4‐[1‐(2‐dodecyl‐1,3‐dioxo‐2,3‐dihydro‐1H‐benzo[de]isoquinolin‐6‐yl)‐3‐(4‐nitrophenyl)‐4,5‐dihydro‐1H‐pyrazol‐5‐yl]phenyl 2‐bromo‐2‐methylpropanoate (IN) as an electron acceptor (A) and a monomer 2‐(9H‐carbazole‐9‐yl)‐ethyl methacrylate (MCz) as an electron donor (D) were simultaneously introduced into two different D–A polymer systems by using the end‐functionalizing or blending method. The mass percentage of IN in the end‐functionalized polymer PMCz‐IN and the mixed polymer composite PMCz+IN were both controlled at approximately 1.0 wt %. The optical, electrochemical, and surface morphology properties of the two polymeric films prepared by means of spin‐coating technology were comparatively investigated. Sandwich devices based on PMCz‐IN and PMCz+IN demonstrated nonvolatile write‐once‐read‐many‐times memory (WORM) and volatile static random access memory (SRAM) characteristics, respectively, which were further verified by the Kelvin probe force microscopy (KPFM) measurements. The proposed memory mechanism could be attributed to the formation of a stable charge‐transfer (CT) complex for PMCz‐IN and an unstable CT complex for PMCz+IN. Furthermore, the different distribution of IN in the two polymeric films might be the main reason for the stability of the CT complex.
Mindfulness‐Based Cognitive Therapy for Psychosis: Measuring Psychological Change Using Repertory Grids
Authors: Randal Chloe , Bucci Sandra , Morera Tirma , Barrett Moya , Pratt Daniel 
Published: June 2015

There are an increasing, but limited, number of studies investigating the benefits of mindfulness interventions for people experiencing psychosis. To our knowledge, changes following mindfulness for psychosis have not yet been explored from a personal construct perspective. This study had two main aims: (i) to explore changes in the way a person construes their self, others and their experience of psychosis following a Mindfulness‐Based Cognitive Therapy (MBCT) group; and (ii) to replicate the findings of other studies exploring the feasibility and potential benefits of MBCT for psychosis. Sixteen participants, with experience of psychosis, completed an 8‐week MBCT group. Participants completed pre‐group and post‐group assessments including a repertory grid, in addition to a range of outcome measures. There was some evidence of changes in construing following MBCT, with changes in the way participants viewed their ideal self and recovered self, and an indication of increased self‐understanding. Improvements were found in participants' self‐reported ability to act with awareness and in recovery. This study demonstrates the feasibility and potential benefits of MBCT groups for people experiencing psychosis. Furthermore, it provides some evidence of changes in construal following MBCT that warrant further exploration. Large‐scale controlled trials of MBCT for psychosis are needed, as well as studies investigating the mechanisms of change. Copyright © 2015 John Wiley & Sons, Ltd.Key Practitioner Message

MBCT may contribute to change in individuals' perceptions and increase self‐understanding.
The study highlights the importance of measuring change in recovery following MBCT.
Findings support the need for person‐centred approaches to assessment and monitoring of personal change following therapy.
Similar studies using a control group are needed in order to identify whether the changes found are attributable to participation in an MBCT group.
Copyright © 2015 John Wiley & Sons, Ltd.
High‐voltage compliant microelectrode array drivers for intracortical microstimulation
Authors: Hasanuzzaman Md. , Raut Rabin , Sawan Mohamad 
Published: June 2015

SummaryWe present in this paper two low‐power high‐impedance microelectrode array drivers (MEDs) dedicated for visual intracortical microstimulation. These output stages of a new microstimulator are highly configurable and able to deliver higher compliance voltage (20 V for anodic and cathodic phases) across microelectrode‐tissue interface impedance compared with previously reported designs. Each MED is featured with a high‐voltage switch‐matrix, 3.3 V/20 V current mirrors, an on‐chip 32‐bit serial‐in parallel‐out shift register, and the new forbidden state logic circuits. Both systems are able to deliver eight bipolar or 16 monopolar stimulation simultaneously. The first MED is able to deliver one stimulation current level and the second one provides four different current amplitudes simultaneously to 16 electrodes. Two microchips have been designed and fabricated using Teledyne DALSA 0.8 µm 5V/ 20v double‐diffused metal‐oxide‐semiconductor field‐effect transistor (Teledyne DALSA Semiconductor, Bromont, Québec, Canada) technology to meet the required high‐voltage compliance. The nominal values of largest supply voltages are ±10 V. The maximum stimulation current per input channel is 400 μA and per output channel through an emulated microelectrode impedance of 100 kΩ is 100 μA. The measured output compliance voltage is 10 V/phase (anodic or cathodic) for the specified supply voltages. Increment of supply voltages to ±13 V allows 220 μA stimulation current per output channel enhancing the output compliance voltage up to 20 V/phase. The measured quiescent power consumptions of the proposed microelectrode array drivers are 316 and 735 μW, respectively. Post‐layout simulation and measurement results of two MEDs and comparison with other designs have been reported in this paper. Copyright © 2015 John Wiley & Sons, Ltd.
Clock gating methodologies and tools: a survey
Authors: Pouiklis Georgios , Sirakoulis Georgios Ch. 
Published: June 2015

SummaryClock gating (CG) is a widely used design method for reducing the dynamic power consumption in digital circuits. Although it is a mature technique, theoretical work and tools for its application are still evolving and considered a matter of ongoing research, due to its significant effect in the overall power of the designs under study. This paper introduces a detailed review of the spectrum of CG approaches, theoretical and practical, from an architectural and register transfer level to synthesis, place and route, and testing issues. Furthermore, tools availability, limitations, and requirements concerning CG are examined for each design flow step. Conclusively, an evaluation of the presented techniques and literature is provided, estimating their usefulness and identifying areas for future research, exploration, and automation. Copyright © 2015 John Wiley & Sons, Ltd.
Biological variation of the cardiac index in patients with stable chronic heart failure: inert gas rebreathing compared with impedance cardiography
Authors: Täger Tobias , Fröhlich Hanna , Franke Jennifer , Slottje Karen , Horsch Andrea , Zdunek Dietmar , Hess Georg , Dösch Andreas , Katus Hugo A. , Wians Frank H. , Frankenstein Lutz 
Published: June 2015

AbstractAimsIn chronic heart failure (CHF), changes in cardiac function define the course of the disease. The cardiac index (CI) is the most adequate indicator of cardiac function. Interpretation of serial CI measurements, however, requires knowledge of the biological variation of CI. Because measurements of CI can be confounded by the clinical situation or the method applied, biological variation might be subject to the same confounders.Methods and resultsWe prospectively included 50 CHF patients who met rigid criteria for clinical stability. CI was measured by both inert gas rebreathing (IGR) and impedance cardiography (ICG) in weekly intervals over 3 weeks—each measurement performed at rest (IGRrest/ICGrest) and during low‐exercise 10 Watt pedalling (IGR10W/ICG10W). Intra‐class correlation coefficients (ICCs), reference change values, and minimal important differences of CI were determined for IGRrest, ICGrest, IGR10W, and ICG10W. Impedance cardiography and IGR showed moderate agreement at rest (20% (6–36)) and good agreement at 10 Watt (−4% (−23–16)). Depending on time interval, measurement modality for CI, and mode, ICC ranged between 0.42 and 0.78, ICC values for IGR were lower than those for ICG. Reference change value ranged between 3 and 15%, and minimal important difference ranged between 0.2 and 0.5 L/min/m2. Values for IGR were lower at rest and higher at 10 Watt than those for ICG.ConclusionNon‐invasive measurements of CI are stable over time. Measurement modalities for CI, however, are not interchangeable. Biological variation is less pronounced when obtained by ICG. The influence of low‐level exercise on stability of CI depends on the measurement modality.
Water‐Soluble, Monodisperse, Lanthanide‐Doped Y(Gd)VO4 Nanocrystals as Promising Multimodal Bioprobe
Authors: Chen Cailing , Li Chunguang , Li Tao , Liu Jianhua , Huang He , Bai Tianyu , Wang Zhaorui , Shi Zhan , Feng Shouhua 
Published: June 2015

AbstractMonodisperse and water‐soluble lanthanide (Ln3+)‐doped Y(Gd)VO4 nanocrystals (NCs) have been successfully synthesized by a fast, facile, and environmentally friendly microwave‐assisted route with poly(acrylic acid) as the surfactant. The Y(Gd)VO4:5 %Ln3+ (Ln = Eu, Dy, Sm) NCs have unique fluorescence properties and polydimethylsiloxane (PDMS)‐based white solid nanocomposites containing YVO4:5 %Eu3+ NCs show red emission upon UV irradiation. GdVO4 NCs can act as CT and MRI contrast agents as a result of their magnetic and X‐ray absorption properties. A layer of SiO2 was coated onto the surfaces of the nanoparticles and MTT assays were carried out to test the cytotoxicity of the YVO4@SiO2 and GdVO4 NCs. The results indicate that the Y(Gd)VO4 NCs have potential in multimodal optical/MRI/CT bio‐imaging.
Bismuth(III)‐Promoted Acetylation of Thio­ethers into Thioacetates
Authors: Jevric Martyn , Petersen Anne Ugleholdt , Mansø Mads , Madsen Anders Østergaard , Nielsen Mogens Brøndsted 
Published: June 2015

AbstractThe thioacetate group is extensively employed as an anchoring group for attachment of molecules onto gold surfaces or between electrodes in molecular electronics. On account of its ready hydrolysis, it is often incorporated in the last step of a synthetic sequence from the corresponding tert‐butyl thioether. Here we present a particularly convenient method for this conversion using AcCl in combination with Bi(OTf)3, which is known as an environmentally friendly salt. A large variety of redox‐active and photoactive substrates with tert‐butyl thioether end‐cap(s) was prepared, including molecules incorporating dithiafulvene, dicyanoethylene, dihydroazulene, fulleropyrrolidine, and triazole units, and successfully subjected to a BiIII promoted conversion into products with thioacetate end‐cap(s). The azide group could also withstand these conditions, which allowed us to prepare S‐(4‐azidophenyl) ethanethioate that presents a convenient building block for subsequent CuAAC reactions.
Scope and Mechanistic Limitations of a Sonogashira Coupling Reaction on an ­Imidazole Backbone
Authors: Sandtorv Alexander H. , Bjørsvik Hans‐René 
Published: June 2015

AbstractA Sonogashira coupling reaction method to join terminal alkynes to the imidazole backbone was developed and investigated. The method exhibits good functional group tolerance and provides target 4‐alkynylated imidazoles in 70–93 % yield. The alkyne reagents were characterized by means of DFT calculations, from which electrostatic potential surfaces (EPS) were produced. A clear correlation between the EPS of the triple bond and the success of the coupling reaction was revealed. If the EPS is in range –94 to –105 kJ mol–1 the coupling is successful. An unsuccessful class of reagents (alkynols) was made compatible by means of an auxiliary group (tert‐butyldimethylsilyl). EPSs of these modified reagents then resembled those of the model and these auxiliary‐assisted reagents then coupled successfully in excellent yields.
RhIII‐Catalyzed Olefination of 2‐Aryloxy­pyridines Using 2‐Pyridyloxyl as the Removable Directing Group
Authors: Borah Arun Jyoti , Yan Guobing , Wang Lianggui 
Published: June 2015

AbstractAn efficient RhIII‐catalyzed trans selective ortho‐olefination of 2‐aryloxypyridines has been developed. The catalytic system is very effective for olefination of differently substituted 2‐aryloxypyridines with acrylates, acrylamide and styrenes and exhibits broad compatibility with assorted olefinic coupling partners. Although acrylates and acrylamide give rise to trans‐olefinated products in MeOH, styrenes provided the trans products under solvent free reaction conditions. Interestingly, in olefinations with ethyl acrylate, the aryloxypyridine compound bearing keto functionality at the ortho position was found to undergo directing group cleavage to afford the olefinated phenol product directly.