bluuebunny/crossref_metadata_2025_split huggingface dataset:
Docking studies of Physalis peruviana ethanol extract using molegro virtual docker on insulin tyrosine kinase receptor as antidiabetic agent
Authors: Puspaningtyas Ayik Rosita 
Published: April 2014

Physalis peruviana Linn in Indonesia was better known as ciplukan, based on information from urban people in Indonesia is as antidiabetic. In the previeous studies, the levels of blood glucose in animals experimental of Physalis peruviana quantified with glucometer and compared with oral antidiabetic drugs gliclazide, showed that Gliclazide was decrease more levels of glucose significantly than ethanol extract of Physalis peruviana. We have done molecular docking using Molegro Virtual Docker (MVD) on ethanol extract of Physalis peruviana and gliclazide to compare between in silico and in vivo studies. Based on studies before the main content of the ethanol extract of Physalis peruviana were withanolide, 4-OH-withanolide, and perulactone. In this study the results showed that gliclazide had been better bond in insulin tyrosine kinase receptor than main content of Physalis peruviana which can be seen from Moldock score 105.217 and Rerank score -68,2931 means that the energy was lower and more stable binding. Moldock Score of main content Physalis peruviana (withanolide, 4-OH-withanolide, and perulactone) were -93.5472; 70.5843; 88.7881, respectively. Rerank score of main content Physalis peruviana (withanolide, 4-OH-withanolide, and perulactone) were -61.5149; -67.5345; -65.7979, respectively. The hydrogen bonds of withanolide, 4-OH-withanolide, perulactone and gliclazide with amino acid of insulin tyrosine kinase receptor were Phe 1186 and Thr 1186. Finally, in the 3D MVD visualization between main content of ethanol extract of Physalis peruviana and gliclazide can be concluded that interaction of gliclazide was more harmonious than main content of ethanol extract Physalis peruviana.DOI: http://dx.doi.org/10.3329/icpj.v3i5.18534 International Current Pharmaceutical Journal, April 2014, 3(5): 265-269
Hepatoprotective effect of Ecballium Elaterium fruit juice against paracetamol induced hepatotoxicity in male albino rats
Authors: Elmhdwi Maraia Farag , Muftah Saleh Mosbah , El tumi Salem Gaber , Elslimani Fatma Al-zaroug 
Published: April 2014

This study was designed to investigate the antioxidant and hepatoprotective activity of Ecballium elaterium "Fruit juice" extract against paracetamol induced hepatotoxicity in male albino rats. The hepatotoxicity was induced by acetaminophen (PCM) at dose of 400 mg/kg in male albino rats. It was administered orally once a day, every 48 h at the same time for twenty two days. The biochemical liver functional tests ALT, AST, ALP, total bilirubin, total protein, antioxidant enzymes (GR, GPx, CAT, SOD), and histopathological changes were examined. Our results showed that Levels of liver enzymes ALT, AST, ALP, G-GT and total bilirubin and MDA level were significantly enhanced by administration of acetaminophen and level of total protein while antioxidant enzymes "GR, GPx, CAT, SOD" were decreased. However, the pretreatment with The E. elaterium "fruit juice" at 1 ml/kg orally revealed attenuation of serum ALT, AST, ALP. The histopathological studies also supported the protective properties of E. elaterium "fruit juice". The area of necrosis and degeneration of hepatocytes were observed in the toxic group. The prophylactic and curative groups showed a marked protective effect with decreased necrotic zones and hepatocellular degeneration. The present results clearly demonstrate the marked antihepatotoxic effects of E. elaterium "fruit juice" extract through its antioxidant activity on acetaminophen induced hepatotoxicity in rats.DOI: http://dx.doi.org/10.3329/icpj.v3i5.18535 International Current Pharmaceutical Journal, April 2014, 3(5): 270-274
The Importance of Web Archives for Humanities
Authors: Gomes Daniel , Costa Miguel 
Published: April 2014

The web is the primary means of communication in developed societies. It contains descriptions of recent events generated through distinct perspectives. Thus, the web is a valuable resource for contemporary historical research. However, its information is extremely ephemeral. Several research studies have shown that only a small amount of information remains available on the web for longer than one year. Web archiving aims to acquire, preserve and provide access to historical information published online. In April 2013, there were at least sixty four web archiving initiatives worldwide. Altogether, these archived collections of web documents form a comprehensive picture of our cultural, commercial, scientific and social history. Web archiving has also an important sociological impact because ordinary citizens are publishing personal information online without preservation concerns. In the future, web archives will probably be the only source of personal memories to many people. We provide some examples of tools that facilitate historical research over web archives highlighting their potential for Humanities.
Percutaneous thermal microwave ablation of thyroid nodules
Authors: Happel C. , Heck K. , Ackermann H. , Grünwald F. , Korkusuz H. 
Published: April 2014

SummaryMicrowave ablation (MWA) is a new minimal invasive method for thermal ablation of benign thyroid nodules. In contrast to well-established radiofrequency ablation (RFA), MWA offers several advantages with similarly successful results. There has not been any use of functional imaging with 99mTc-per- technetate and 99mTc-MIBI-scans as a mere qualitative analysis of this imaging in the field of MWA in Europe until now. The aim of this study has been to demonstrate the feasibility of MWA as well as the applicability of functional imaging to verify effectiveness with a centerspecific score. Patients, methods: 11 patients (5 women, 6 men, average age 62.3 years) with 18 benign thyroid nodules were treated. MWA was operated under local anesthesia with a system working in a wavelength field of 902 to 928 MHz (Avecure MWG881, MedWaves, Inc. San Diego, CA). Pre- and postablative scans were controlled by two specialists in nuclear medicine with longtime work experience. Results: A center specific functional imaging score (CSFIS) was defined, a decrease of 1.4 points at an average was noticeable (range 1-3 points). In 66.7% (n = 12) of all nodules the score decreased by 1 point, 27.8% (n = 5) by 2 points and 5.6% (n = 1) by 3 points. The treatment was well tolerated and no severe complications were observed. Conclusion: The preliminary data suggests that MWA is an effective method to treat benign thyroid nodules. Functional imaging is a promising technique for early verification of effectiveness of thermal ablation.
Optimisation of key performance measures in air cargo demand management
Authors: May Alexander , Anslow Adrian , Ojiako Udechukwu , Wu Yue , Marshall Alasdair , Chipulu Maxwell 
Published: April 2014

This article sought to facilitate the optimisation of key performance measures utilised for demand management in air cargo operations. The focus was on the Revenue Management team at Virgin Atlantic Cargo and a fuzzy group decision-making method was used. Utilising intelligent fuzzy multi-criteria methods, the authors generated a ranking order of ten key outcome-based performance indicators for Virgin Atlantic air cargo Revenue Management. The result of this industry-driven study showed that for Air Cargo Revenue Management, ‘Network Optimisation’ represents a critical outcome-based performance indicator. This collaborative study contributes to existing logistics management literature, especially in the area of Revenue Management, and it seeks to enhance Revenue Management practice. It also provides a platform for Air Cargo operators seeking to improve reliability values for their key performance indicators as a means of enhancing operational monitoring power.
The diabetic patient in Ramadan
Authors: Chamsi-Pasha Hassan , Aljabri Khalid S 
Published: April 2014

AbstractDuring the month of Ramadan, all healthy, adult Muslims are required to fast from dawn to sunset. Fasting during Ramadan involves abstaining from food, water, beverages, smoking, oral drugs, and sexual intercourse. Although the Quran exempts chronically ill from fasting, many Muslims with diabetes still fast during Ramadan. Patients with diabetes who fast during the month of Ramadan can have acute complications. The risk of complications in fasting individuals with diabetes increases with longer periods of fasting. All patients with diabetes who wish to fast during Ramadan should be prepared by undergoing a medical assessment and engaging in a structured education program to undertake the fast as safely as possible. Although some guidelines do exist, there is an overwhelming need for better designed clinical trials which could provide us with evidence-based information and guidance in the management of patients with diabetes fasting Ramadan.
Des images et des sciences
Authors: Drouin Anne-Marie 
Published: April 2014

De las imágenes y de las ciencias

Las ciencias tanto en su presentación vulgarizada que en su transmisión entre pares o en su fase de elaboración, utilizan largamente las imágenes.
La enseñanza de la ciencias como la mayor parte de las enseñanzas, se sirve de los esquemas explicativos, de diagramas y curvas, que ilustran los manuales o que los alumnos son incitados a construir.
Abordar el papel de las imágenes en las ciencas no excluye un análisis de la imágen por ella misma. En efecto, las reglas del código y el descifrado, la relación entre lo conceptual y lo figurado, el poder y los límites de la esquematización, la distancia controlada entre lo real y su imagen fotografiada o dibujada, todo esto existe y se analiza, sin tener en cuenta el tipo de contenido. Queda que por las ciencias, en tren de hacerse o mostrando sus resultados, las imágenes juegan roles diversos e importantes, contradictorias algunas veces, pero necesarias, y del cuál sera importante poder hacer aparecer el papel específico.
Adaptation et théorie de l'évolution
Authors: Lacombe Geneviève 
Published: April 2014

Adaptación y teoría de la evolución Geneviève Lacombe
La autora nos propone un análisis critico de los programas de biología de segundo ciclo, poniendo en evidencia la falta de perspectiva evolucionista. Otros países se baten por ensebar o no enseríar las teorías de la evolución. El problema no se plantea en Francia : nuestra enseñanza en el liceo es absolutamente no evolucionista (y de ese hecho fijista ?) guardando de las teorías de la evolución solamente la noción de adatación.
El texto remarca la reducción positivista de la noción de adaptación a través la presentación de los manuales del liceo.
Travail autonome au lycée et élaboration du concept de respiration
Authors: Guyon Jeanine 
Published: April 2014

Trabajo autónomo y elaboración del concepto de respiración

La innovación pedagógica conducida en el liceo, que es descripta aquí, articulaba en un proyecto de elaboración colectiva del concepto des respiración, diversos modalidades de trabajo. Los alumnos han conducido un trabajo de investigación en equipos, ellos pusieron en relación los resultados aportados por cada equipo, el profesor dió las informaciones complementarias. Todo este trabajo ha permitido una estructuración de conocimientos por el conjunto de la clase.
El objetivo del profesor era esencialmente de facilitar la adquisición personal de conocimientos. Es por eso que el acento fue puesto en el análisis sobre la evolución de las concepciones de los alumnos en relación a la respiración.
Use of Eyeglasses among Children in Elementary School: Perceptions, Behaviors, and Interventions Discussed by Parents, School Nurses, and Teachers during Focus Groups
Authors: Kodjebacheva Gergana Damianova , Maliski Sally , Coleman Anne L. 
Published: April 2014

Purpose. To investigate the perceptions, behaviors, and recommendations that parents, school nurses, and teachers have regarding children's use of eyeglasses. Approach. Focus groups with parents, school nurses, and teachers were conducted. Setting. The study took place in one Southern California school district. Participants. There were 39 participants, including 24 parents, seven school nurses, and eight teachers. Method. An experienced moderator guided the focus group discussions. Transcripts were analyzed using grounded theory techniques. Results. Participants perceive visual impairment as a serious problem in the development of children. The lack of eyeglasses may lead to problems such as tiredness, headaches, inability to focus on school work, and decreased reading speed. Participants experienced disappointment, unhappiness, worry, and concern when they realized they needed eyeglasses at a young age. Negative societal perceptions toward eyeglasses, lack of eye doctors in minority communities, parental perceptions that children do not need eyeglasses, and peer bullying of children wearing eyeglasses are key obstacles to children's use of eyeglasses. Participants suggest school and national campaigns featuring respected public figures who wear eyeglasses to promote positive attitudes toward eyeglasses. Conclusion. Parents and teachers who closely follow the academic development of children have observed that visual impairment has negative consequences for the scholastic achievement of children. They recommend interventions to promote the attractiveness of eyeglasses in society. The participants discuss the need for a national preventative message for eye care similar to the message for dental care. The public health message should emphasize the importance of embracing and respecting differences among individuals.
Developing Clinical Decision Support within a Commercial Electronic Health Record System to Improve Antimicrobial Prescribing in the Neonatal ICU
Authors: Cato K. , Sheehan B. , Patel S. , Duchon J. , DeLaMora P. , Ferng Y.H. , Graham P. , Vawdrey D.K. , Perlman J. , Larson E. , Saiman L. , Hum R.S. 
Published: April 2014

SummaryObjective: To develop and implement a clinical decision support (CDS) tool to improve antibiotic prescribing in neonatal intensive care units (NICUs) and to evaluate user acceptance of the CDS tool.Methods: Following sociotechnical analysis of NICU prescribing processes, a CDS tool for empiric and targeted antimicrobial therapy for healthcare-associated infections (HAIs) was developed and incorporated into a commercial electronic health record (EHR) in two NICUs. User logs were reviewed and NICU prescribers were surveyed for their perceptions of the CDS tool.Results: The CDS tool aggregated selected laboratory results, including culture results, to make treatment recommendations for common clinical scenarios. From July 2010 to May 2012, 1,303 CDS activations for 452 patients occurred representing 22% of patients prescribed antibiotics during this period. While NICU clinicians viewed two culture results per tool activation, prescribing recommendations were viewed during only 15% of activations. Most (63%) survey respondents were aware of the CDS tool, but fewer (37%) used it during their most recent NICU rotation. Respondents considered the most useful features to be summarized culture results (43%) and antibiotic recommendations (48%).Discussion: During the study period, the CDS tool functionality was hindered by EHR upgrades, implementation of a new laboratory information system, and changes to antimicrobial testing methodologies. Loss of functionality may have reduced viewing antibiotic recommendations. In contrast, viewing culture results was frequently performed, likely because this feature was perceived as useful and functionality was preserved.Conclusion: To improve CDS tool visibility and usefulness, we recommend early user and information technology team involvement which would facilitate use and mitigate implementation challenges.Citation: Hum RS, Cato K, Sheehan B, Patel S, Duchon J, DeLaMora P, Ferng YH, Graham P, Vawdrey DK, Perlman J, Larson E, Saiman L. Developing clinical decision support within a commercial electronic health record system to improve antimicrobial prescribing in the neonatal ICU. Appl Clin Inf 2014; 5: 368–387 http://dx.doi.org/10.4338/ACI-2013-09-RA-0069
Influence of weakly H-subgroups of minimal subgroups on the structure of finite groups
Authors: Al-Shomrani Mohammed Mosa 
Published: April 2014

Let G be a finite group. A subgroup H of G is called an H-subgroup in G if NG(H) \ Hg H for all g in G. A subgroup H of G is called a weakly H-subgroup in G if there exists a normal subgroup K of G such that G = HK and H \ K is an H-subgroup in G. In this paper, we use weakly H-subgroup condition on minimal subgroups to study the structure of the finite group G. Some earlier results are improved and extend.
Poetry Is Theft
Authors: Galvin Rachel 
Published: April 2014

Abstract
This article explores poetic practices of copying and recycling that follow a “cannibalistic” logic. Taking a cue from theories of literary relationality elaborated by Edward Said, Haroldo De Campos, Oswald De Andrade, Édouard Glissant, Jorge Luis Borges, and Marcus Boon, I examine innovations in the work of poets such as Mónica de la Torre, Timothy Donnelly, Terrance Hayes, Mark McMorris, Haryette Mullen, M. NourbeSe Philip, and Wendy Walker. While it is unusual to read North American poetry in connection with postcolonial and Latin American literary theory, my article's method enacts the same kind of poetic circuit that I am interested in exploring. Seeking to build on recent comparative approaches to twentieth-century poetry I argue that tracing dialogues and conceptual affinities across linguistic and regional boundaries is crucial for understanding the development of experimental poetics in the American Hemisphere.
English Before Engrish:
Authors: Fickle Tara 
Published: April 2014

Abstract
This article interrogates the limits of the “playful” genre that Timothy Yu has recently defined as Asian American experimental or avant-garde poetry. Through the work of John Yau, Brian Kim Stefans, Fred Wah, and others, I demonstrate the centrality of Wittgensteinian poetics to the aesthetic innovations of contemporary Asian North American poets whose language games challenge normative assumptions about the relationship between language, literature, and identity.
Real-Life Motor Training Modifies Spatial Performance: The Advantage of Being Drummers
Authors: PELLICANO ANTONELLO , IANI CRISTINA , RUBICHI SANDRO , RICCIARDELLI PAOLA , BORGHI ANNA M. , NICOLETTI ROBERTO 
Published: April 2014

Abstract
We compared the performance of skilled drummers with that of nondrummers and nonmusicians in the Simon and spatial stimulus—response compatibility (SRC) tasks to investigate whether and to what extent spatial performance can be modified by motor behaviors acquired in real life. Drummers were chosen because, compared with other musicians and the general population, their efficient performance depends mainly on the processing of spatial information. Although the Simon effect was equivalent for the three groups, the spatial SRC effect was less pronounced in drummers. The advantage was present even when feet were used as responding effectors, suggesting a central locus of the effect. These results suggest that spatial stimulus—response translations are influenced by real-life motor training, with drummers’ training speeding up the intentional stimulus—response translations when stimulus and response locations are on opposite sides.
Characterizing perceptual learning using regression statistics: Development of a perceptual calibration index
Authors: CABE PATRICK A. , WAGMAN JEFFREY B. 
Published: April 2014

Abstract
Perceptual learning, improvement in perceptual skill with practice, can improve both accuracy and consistency of perceptual reports. Regression statistics can quantify ongoing calibration of perceptible scalar properties (i.e., improvements in accuracy and consistency) because, ideally, actual and perceived values are linearly related. Changes in variance accounted for (r2) track changes in consistency, and changes in both slope and intercept track changes in accuracy. Conjoint changes in all three regression statistics, obscured in separate plots, can be seen simultaneously in a perceptual calibration state space diagram, with the regression statistics as axes, in which an attractor (r2 = 1.00, slope = 1.00, intercept = 0.00) represents optimal performance. Decreases in the distance between the attractor and successive points in the state space, each representing perceptual performance, quantify perceptual learning; that distance is a perceptual calibration index. To show the utility of the perceptual calibration index, we illustrate its use in an experiment on wielding hand-held objects.
The impact of domain and subject specialization on knowledge organization
Authors: WYATT JEFFREY , RABINOWITZ MITCHELL 
Published: April 2014

Abstract
Thematic organization is the association of information that is observed within a given time frame or event, and taxonomic organization is characterized by class membership based on featural overlap. Research in cognitive psychology has suggested a developmental progression in preference from thematic organization to taxonomic organization, with a preference for taxonomic organization seen as cognitively more advanced. However, recent research has found thematic preferences in adults and shown that organizational preference can be influenced by context and experience. This study expanded on previous findings of individual differences and explored preferences across different domains. Specifically, preferences for knowledge organization were measured between student type (history and psychology) and across content type (general and history). The results indicated that history material was more likely to be organized thematically than general material.
How the behavioral approach system predicts everyday life outcomes
Authors: IZADIKHAH ZAHRA , JACKSON CHRIS J. 
Published: April 2014

Abstract
This study tested crucial components of Gray’s reinforcement sensitivity theory that have generally been overlooked in the literature. We tested whether the perceived amount of reward moderates the behavioral approach system (BAS) and the importance of reward mediates BAS in the prediction of job satisfaction and organizational commitment. Results from 514 participants employed in part-time and full-time jobs provided support for our model, such that the indirect effect of BAS through the importance of reward was strongest when reward was provided. This model advances our understanding of reinforcement sensitivity theory and offers a solid foundation for predicting outcomes in everyday life.
Adaptive memory: Nature’s criterion and the functionalist agenda
Authors: NAIRNE JAMES S. , PANDEIRADA JOSEFA N. S. 
Published: April 2014

AbstractMemory researchers traditionally ignore function in favor of largely structural analyses. For example, it is well known that forming a visual image improves retention, and various proximate mechanisms have been proposed to account for the advantage (e.g., elaboration of the memory trace), but next to nothing is known about why memory evolved such sensitivities. Why did nature craft a memory system that is sensitive to imagery or the processing of meaning? Functional analyses are critical to progress in memory research for two main reasons: First, as in applied research, functional analyses provide the necessary criteria for measuring progress; second, there are good reasons to believe that modern cognitive processes continue to bear the imprint of ancestral selection pressures (i.e., cognitive systems are functionally designed). We review empirical evidence supporting the idea that memory evolved to enhance reproductive fitness; as a consequence, to maximize retention in basic and applied settings it is useful to develop encoding techniques that are congruent with the natural design of memory systems.