bluuebunny/crossref_metadata_2025_split huggingface dataset:
Utility of Anti–Melanoma Differentiation–Associated Gene 5 Antibody Measurement in Identifying Patients With Dermatomyositis and a High Risk for Developing Rapidly Progressive Interstitial Lung Disease: A Review of the Literature and a Meta‐Analysis
Authors: Chen Zhiyong , Cao Mengshu , Plana Maria Nieves , Liang Jun , Cai Hourong , Kuwana Masataka , Sun Lingyun 
Published: February 2013

ObjectiveTo assess the utility of anti–melanoma differentiation–associated gene 5 (anti‐MDA5) antibody measurement for predicting a risk for developing rapidly progressive interstitial lung disease (RP‐ILD) in patients with polymyositis/dermatomyositis (PM/DM).MethodsA single‐center cohort of 64 consecutive Chinese patients with PM/DM was examined. Serum anti‐MDA5 antibody was measured by enzyme‐linked immunosorbent assay. For meta‐analysis, we searched PubMed and the Institute for Scientific Information Web of Knowledge for original studies that measured anti‐MDA5 antibodies in patients with PM/DM. We calculated pooled sensitivity, specificity, diagnostic odds ratio (DOR), and the summary receiver operating characteristic (sROC) curve.ResultsIn Chinese patients, anti‐MDA5 antibodies were detected in 26 patients with classic DM or clinically amyopathic DM (CADM). Compared with anti‐MDA5–negative patients, anti‐MDA5–positive patients showed a higher prevalence of RP‐ILD (P = 0.001). In a total of 233 patients with anti‐MDA5 antibody, derived from 16 studies, a higher frequency of CADM was found in Japanese than in non‐Japanese patients (74.7% versus 39.2%; P = 1.2 × 10−7). Meta‐analysis revealed that the pooled sensitivity and specificity of anti‐MDA5 antibody for RP‐ILD was 77% (95% confidence interval [95% CI] 64–87%) and 86% (95% CI 79–90%), respectively. The pooled DOR was 20.41 (95% CI 9.02–46.20) with a favorable area under the sROC curve of 0.89 (95% CI 0.63–0.98).ConclusionDetection of anti‐MDA5 antibody is a valuable tool for identifying DM patients with a high risk for developing RP‐ILD, but the distribution of classic DM and CADM in patients with this antibody varies among ethnic groups.
Medial temporal lobe amnesia impairs performance on a free association task
Authors: Sheldon Signy , Romero Kristoffer , Moscovitch Morris 
Published: February 2013

AbstractA growing body of evidence suggests that the hippocampus contributes to performance (or is implicated) in non‐memory domains from perception to problem solving. In a previous study we found that hippocampal contribution to exemplar generation in a fluency task was determined jointly by the open‐endedness of the task and its ability to elicit episodic memories (Sheldon and Moscovitch (2012) Hippocampus 22:1451–1466). In the current study, we extend these observations by exploring the role of the hippocampus in generative, goal‐directed open‐ended thought in patients with medial temporal lobe (MTL) amnesia on a free association task (think of words as they come to mind). Patients and control participants were asked to associate freely for one minute to cue words that varied in the open‐endedness of the responses they elicited (greater for low‐ than high‐frequency words), and in the ease with which episodic memories were evoked (greater for high imageable than low imageable words). As predicted, MTL amnesia patients generated fewer words than control participants when cues were highly imageable and low in frequency, but performed equivalently to them in the other conditions. These results support our prediction that the hippocampus contributes to free association, and possibly more generally to other generative tasks that are open‐ended, creative, or that elicit the use of contextual and likely episodic memories in order to derive relevant information. © 2013 Wiley Periodicals, Inc.
Simulation of mesogenic diruthenium tetracarboxylates: Development of a force field for coordination polymers of the MMX type
Authors: Castro Maria Ana , Roitberg Adrian E. , Cukiernik Fabio D. 
Published: February 2013

AbstractA classical molecular mechanics force field, able to simulate coordination polymers (CP) based on ruthenium carboxylates (Ru2(O2CReq)4Lax) (eq = equatorial group containing aliphatic chains, Lax= axial ligand), has been developed. New parameters extracted from experimental data and quantum calculations on short aliphatic chains model systems were included in the generalized AMBER force field. The proposed parametrization was evaluated using model systems with known structure, containing either short or long aliphatic chains; experimental results were reproduced satisfactorily. This modified force field, although in a preliminary stage, could then be applied to long chain liquid crystalline compounds. The resulting atomistic simulations allowed assessing the relative influence of the factors determining the CP conformation, determinant for the physical properties of these materials. © 2013 Wiley Periodicals, Inc.
Response to comments on ‘Influences of the Bermuda High and atmospheric moistening on changes in summer rainfall in the Atlanta, Georgia region, the United States’
Authors: Diem Jeremy E. 
Published: February 2013

ABSTRACTResearchers have come to differing conclusions about multi‐decadal changes in the position of the western ridge of the Bermuda High during the summer. This communication examines trends for 72 periods within the entire period of record (1948–2012), while also comparing variances in the Western Bermuda High Index (WBHI) and the latitudinal position of the western ridge. The western ridge has not moved significantly eastward or westward over either 1948–2012 or the past 60 years. The western ridge underwent a major westward shift from 1976 to 1977, but it did not stay in that western position during subsequent decades. Over the past 30–40 years, the western ridge has moved significantly eastwards and southwards. Finally, the WBHI, rather than the latitude of the western ridge, has had a definitive increase in variance over time and is the likely cause of increased summer rainfall variability in the southeastern United States.
Comments on ‘Influences of the Bermuda High and atmospheric moistening on changes in summer rainfall in the Atlanta, Georgia region, USA’
Authors: Li Wenhong , Li Laifang , Fu Rong , Deng Yi , Wang Hui 
Published: February 2013

ABSTRACTIn a recent article, Diem (2012) examined the impact of the North Atlantic Subtropical High (NASH) and atmospheric moistening on summer rainfall variability in the Atlanta, Georgia region. In his paper, he indicated that the results concerning the variability of the NASH western ridge discussed in Li et al. (2011) are incorrect. We present new evidence here to show that the comments by Diem (2012) are unjustified; the main conclusions in Li et al. (2011) were drawn according to the data over a 60‐year (1948–2007) and 45‐year (1958–2002) periods of NCEP/NCAR and ERA‐40 reanalysis, whereas conclusions of Diem (2011) were based upon the trend analysis of a similar but different index of the NASH using sub‐periods of 1948–2009 (since late 1970s). The comment emphases the importance of climate dynamics to study precipitation variability over the Southeastern US and further strengthens the conclusions originally put forth in Li et al. (2011): over the last 60 years (1948–2007), the NASH has shown a significant trend of westward movement, and the meridional movement of the NASH western‐ridge (i.e. its latitudinal change) has enhanced in the recent three decades.
A note on “Multistage Methods for Freight Train Classification”
Authors: Briskorn Dirk , Jaehn Florian 
Published: February 2013

AbstractThe paper “Multistage Methods for Freight Train Classification” by Jacob et al. [Networks 57 (2011) 87–105] provides great insight into the theory and practice of sorting procedures at shunting yards. In Jacob et al. [Networks 57 (2011) 87–105] many relevant shunting situations (e.g., single or multiple inbound trains, single or multiple outbound trains, (un)restricted number of tracks, (un)restricted track capacity) are formally specified as optimization problems. Then, for almost all of them either an exact polynomial‐time algorithm or an NP‐hardness proof is provided. However, the case of multiple inbound trains, which is of high practical relevance, is left open. We close this gap by providing a proof of NP‐hardness. © 2013 Wiley Periodicals, Inc. NETWORKS, 2013
DeconRNASeq: a statistical framework for deconvolution of heterogeneous tissue samples based on mRNA-Seq data
Authors: Gong Ting , Szustakowski Joseph D. 
Published: February 2013

Abstract
Summary: For heterogeneous tissues, measurements of gene expression through mRNA-Seq data are confounded by relative proportions of cell types involved. In this note, we introduce an efficient pipeline: DeconRNASeq, an R package for deconvolution of heterogeneous tissues based on mRNA-Seq data. It adopts a globally optimized non-negative decomposition algorithm through quadratic programming for estimating the mixing proportions of distinctive tissue types in next-generation sequencing data. We demonstrated the feasibility and validity of DeconRNASeq across a range of mixing levels and sources using mRNA-Seq data mixed in silico at known concentrations. We validated our computational approach for various benchmark data, with high correlation between our predicted cell proportions and the real fractions of tissues. Our study provides a rigorous, quantitative and high-resolution tool as a prerequisite to use mRNA-Seq data. The modularity of package design allows an easy deployment of custom analytical pipelines for data from other high-throughput platforms.
Availability: DeconRNASeq is written in R, and is freely available at http://bioconductor.org/packages.
Contact: tinggong@gmail.com
Supplementary information: Supplementary data are available at Bioinformatics online.
Draft Genome Sequence of Chromate-Resistant and Biofilm-Producing Strain Pseudomonas alcaliphila 34
Authors: Santopolo Luisa , Marchi Emmanuela , Decorosi Francesca , Galardini Marco , Brilli Matteo , Giovannetti Luciana , Viti Carlo 
Published: February 2013

ABSTRACT

We report the draft genome sequence of
Pseudomonas alcaliphila
34, a Cr(VI)-hyperresistant and biofilm-producing bacterium that might be used for the bioremediation of chromate-polluted soils. The genome sequence might be helpful in exploring the mechanisms involved in chromium resistance and biofilm formation.
Draft Genome Sequences of Three Salmonella enterica Serotype Agona Strains from China
Authors: Zhang Jianmin , Cao Guojie , Xu Xuebin , Jin Huimin , Yang Xiaowei , Allard Marc , Brown Eric , Meng Jianghong 
Published: February 2013

ABSTRACT

Salmonellosis has been one of the major contributors to the global public health burden.
Salmonella enterica
serotype Agona has ranked among the top 10 and top 20 most frequent
Salmonella
serotypes isolated from human sources in China and the United States, respectively. We report draft genomes of three
S.
Agona strains from China.
“The Idea of the Nation Was Superior to Race”: Transforming Racial Contours and Social Attitudes and Decolonizing the French Empire from La Réunion, 1946–1973
Authors: Finch-Boyer Héloïse 
Published: February 2013

Scholars assume the loss of Algeria in 1962 marked the end of French colonialism and a hardening of racialized categories of difference in France, overlooking how race and class categories became more porous in the overseas departments (départements d’outre-mer, or DOMs) after a new, welfare-led, French colonialism was initiated by Prime Minister Michel Debré (elected deputy of La Réunion in 1963). Comparing the provision of social welfare in the DOMs before and after 1962 demonstrates that Debré’s new health insurance, family allocations, and housing laws offered DOM populations improved social mobility beyond colonial-era racial boundaries. Welfare encouraged Réunion Islanders to support political attachment to France and undermined support for DOM autonomy movements. Combining scholarship on decolonization, French welfare, and the social history of La Réunion, the article reevaluates the place of French overseas departments in decolonization history, in studies of French racial categories, and in modern France.
En constatant que la perte de l’Algérie en 1962 a marqué la fin du colonialisme français et instauré, en France Métropolitaine, un durcissement des catégories raciales de différence, les chercheurs négligent que les catégories de race et de classe sont devenues moins rigides dans les DOM après la mise en place d’une nouvelle forme de colonialisme français, axée autour de l’Etat-providence et établie par l’ancien premier ministre Michel Debré (élu député de La Réunion en 1963). Comparer la protection sociale dans les DOM avant et après 1962 démontre que la nouvelle assurance santé, les allocations familiales et les lois anti-bidonvilles ont offert aux populations des DOM une amélioration de la mobilité sociale au-delà des possibilités de l’époque coloniale. L’Etat-providence a encouragé un attachement politique à la France dans la population locale, tout en sapant le soutien aux idées autonomistes. Cet article donne un regard croisé entre l’histoire politique de la décolonisation, l’histoire de la législation sociale et l’histoire sociale de La Réunion afin de réévaluer l’importance des DOM dans l’histoire de la décolonisation, les études des représentations raciales françaises, et dans l’histoire de la France moderne.
Comparative feeding kinematics of tropical hylid tadpoles
Authors: Venesky Matthew D. , Rossa-Feres Denise , Nomura Fausto , Vasconcellos de Andrade Gilda , Pezzuti Tiago L. , Tsutae de Sousa Verônica T. , Anderson Christopher V. , Wassersug Richard J. 
Published: February 2013

Summary
Anuran larvae, which are otherwise simple in shape, typically have complex keratinized mouthparts (i.e., labial teeth and jaw sheaths) that allow them to graze upon surfaces. The diversity in these structures among species presumably reflects specializations that allow for maximal feeding efficiency on different types of food. However, we lack a general understanding of how these oral structures function during feeding. We used high-speed digital imaging (500 Hz) to observe tadpoles of six species from the anuran family Hylidae grazing on a standardized food-covered substrate. Tadpoles of these species vary in the number of labial tooth rows, belong to two different feeding guilds (benthic and nektonic), and inhabit ponds and streams. We confirmed that the labial teeth in these species serve two functions; anchoring the mouth to the substrate and raking material off of the substrate. In general, tadpoles with a larger maximum gape and those with fewer labial tooth rows opened and closed their mouths faster than tadpoles with smaller gape and more tooth rows. Nektonic feeding tadpoles released each of their tooth rows proportionally earlier in the gape cycle compared to benthic feeding tadpoles. Lastly, we found some support for the idea that deformation of the jaw sheaths during a feeding cycle is predictable based on tadpole feeding guild. Collectively, our data show that anatomic (e.g., number of labial teeth) and ecological features (e.g., feeding guild) of tadpoles significantly influence how tadpoles open and close their mouths during feeding.
Individual Attitudes and Shopping Mode Characteristics Affecting the Use of E-Shopping and Related Travel
Authors: Crocco Federica , Eboli Laura , Mazzulla Gabriella 
Published: February 2013

Abstract
New telecommunication technologies and services have caused important challenges on travel behaviour and trip characteristics. Existing literature studies show many different outcomes regarding the effects of the new technologies on the participation of people to their personal activities and related travel; specifically, e-shopping may produce the reduction of shopping trips (substitution effect), but also an increase of trips thanks to the reuse of the travel time saved for other activities and trips (complementarity’s effect). The focus of this study is to analyse the aspects mostly affecting consumer choices of purchasing goods by web or in-store, with the aim of understanding how to operate so that e-shopping can positively modify consumers’ travel behaviour. Our research findings show that individual social and economic factors, consumer attitudes, and shopping mode characteristics influence the usage of online shopping. An experimental survey addressed to a sample of Italian consumers is used in the study.
Assessment of Extremes in Air Temperature Over North-East and West Coast Regions of India
Authors: Tondgimenba Jamir , Shankar De Uday , Krishnakumar Gaddam 
Published: February 2013

AbstractThe projected effect of climate change is the increase of both the frequency and intensity of extreme weather events. An attempt has been made to study the extremes in temperature over two regions of India i.e. North-East Region (NER) and West Coast Region (WCR). A detailed analysis indicated that in the NER, ten stations indicate increase in annual extreme minimum but significant at four stations. Post-monsoon season is very predominant where five stations show significant increase. In the WCR, all the stations indicate increasing trend in annual extreme maximum temperature significant at nine stations. Majority of the stations indicate significant increasing trend in all the seasons except monsoon season.
History of dermatology and venereology in Serbia – Part IV/1: Dermatovenereology in Serbia from 1919 – 1945
Authors: Lalević-Vasić Bosiljka M. , Jovanović Marina 
Published: February 2013

Abstract
After the First World War, Serbia was ravaged and in ruins, whereas the Health Care Service was destroyed. Organization and reorganization of the Health Care Service started with a fight against the spread of infectious diseases. Foundation of specialized health institutions was among the first tasks. As early as 1920, an Outpatient Service forSkin and Venereal Diseases was established and managed by Prof. Đorđe Đorđević. In 1922, after he was appointed as Associate Professor at the newly established Faculty of Medicine in Belgrade, he founded a Clinic for Skin andVenereal Diseases, and acted as its first director. In 1928, a Municipal Outpatient Clinic for Skin and Venereal Diseases was founded, whereas in 1938 a modern organization of the Service was established in a new building. After a break during the I World War, the Dermatovenereology Department of the General Military Hospital in Belgrade, founded in 1909, continued working until the Second World War. In Novi Sad, the City Hospital was founded in 1909, including a Dermatovenereology Department. After the First World War, in 1921, Dr. Jovan Nenadović founded a Department of Skinand Venereal Diseases (100 beds) in the General Public Hospital, as well as, an independent Public Outpatient Clinic for free-of-charge treatment of patients with venereal diseases. In Niš, the first Organization Unit for Venereal Diseases was founded in 1912, but the Department of Venereal Diseases was founded in 1921, and it was managed by Dr. Petar Davidović, while in 1927 a Department of Skin and Venereal Diseases was established within the General PublicHospital. In 1920, a Dermatovenereology Department of the Military Hospital in Niš was established. Apart from these, as early as 1921, there was a total of 7 Outpatient Clinics in Serbia, and in 1923 there were 14 venereal departments, and 1 dermatovenereology department.
Lecanicillium Aphanocladii – A New Species to the Mycoflora of Lithuania and a New Pathogen of Tree Leaves Mining Insects
Authors: Pečiulytė Dalė , Kačergius Audrius 
Published: February 2013

Abstract
Pečiulytė D., Kačergius A., 2012: Lecanicillium aphanocladii - a new species to the mycoflora of Lithuania and a new pathogen of tree leaves mining insects [Lecanicillium aphanocladii - nauja Lietuvos mikofloros rūšis ir naujas medžių lapus minuojančių vabzdžių patogenas pasaulyje]. - Bot. Lith., 18(2); 133-146.
Popular park and city trees horse chestnut, Aesculus hippocastanum L. and small-leaved linden, Tilia cordata Miller suffer from damages of leaf mining moths, Cameraria ohridella Deschka & Dimic 1968 and Lithocolletis issikii Kumata 1825 (= Phyllonorycter issikii Humber 1822 (both Lepidoptera, Gracillariidae), respectively. In 2010-2011, fungi causing moth caterpillar mortality under field conditions were investigated in Vilnius city, Lithuania. Statistical analyses showed high recovery percentage (30.36 % and 31.92 % from C. ohridella and L. issikii caterpillar cadavers, respectively) of a new fungus, which was thereafter identified as Lecanicillium aphanocladii Zare & W. Gams 2001 based on a morphological characteristics and ITS rDNR sequence, which showed 99 % identity with Aphanocladium aranearum (Petch) W. Gams 1971 GenBank accessions No. AF455489 and AF455405 of ribosomal RNA gene (now renamed as L. aphanockladii).
Spiking rate of myenteric neurons recorded from multi‐electrode arrays depending on local microenvironment
Authors: Medert Rebekka , Schuster Anne , Schwarz Lukas Kristoffer , Schwab Tanja , Schaefer Karl‐Herbert 
Published: February 2013

AbstractThe interaction of cells with their microenvironment is an important factor, which influences phenotype, differentiation state and cell function. Interactions between cells and extracellular matrix (ECM) components are of crucial significance, especially for the development of electrical activity in neurons. For this study multi‐electrode arrays were used to examine the influence of different substrates (glass, poly‐D‐lysine (PDL), PDL/laminin and laminin) on myenteric neurons during stimulation with lipopolysaccharide (LPS). The effect of LPS upon neurons grown on PDL/laminin resulted in an increased neuronal activity and calcium influx through L‐type voltage gated calcium channels. Cultures on glass or PDL were not influenced. This demonstrates that the local microenvironment plays an essential role for the electrical potential of myenteric neurons.(© 2013 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Bayesian Optimal Adaptive Estimation Using a Sieve Prior
Authors: ARBEL JULYAN , GAYRAUD GHISLAINE , ROUSSEAU JUDITH 
Published: February 2013

Abstract.We derive rates of contraction of posterior distributions on non‐parametric models resulting from sieve priors. The aim of the study was to provide general conditions to get posterior rates when the parameter space has a general structure, and rate adaptation when the parameter is, for example, a Sobolev class. The conditions employed, although standard in the literature, are combined in a different way. The results are applied to density, regression, nonlinear autoregression and Gaussian white noise models. In the latter we have also considered a loss function which is different from the usual l2 norm, namely the pointwise loss. In this case it is possible to prove that the adaptive Bayesian approach for the l2 loss is strongly suboptimal and we provide a lower bound on the rate.
Study of the effects of spray‐drying on the functionality of probiotic lactobacilli
Authors: Páez Roxana , Lavari Luisina , Audero Gabriela , Cuatrin Alejandra , Zaritzky Noemí , Reinheimer Jorge , Vinderola Gabriel 
Published: February 2013

Three probiotic lactobacilli strains were spray‐dried in 20% (w/v) skim milk and submitted to a simulated gastrointestinal digestion. Fresh or spray‐dried cultures were administered to mice for 5 and 10 days, and Immunoglobulin A (IgA)‐producing cells were enumerated in the small intestine by immunohistochemistry. Spray‐drying significantly enhanced the resistance of Lactobacillus paracasei A13 and Lactobacillus casei Nad to a simulated gastrointestinal digestion (0.96 and 1.95 log orders, respectively), compared with fresh cultures. Also, a significant higher number of IgA‐producing cells were induced by spray‐dried cultures compared with fresh cultures. Spray‐drying is a suitable, but strain‐dependent, technological process for the development of probiotic cultures in skim milk with increased functionality.