bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sibling Gender Dynamics and Childhood Malnutrition in Ghana
Authors: Mensah Peter Annor , Sawyerr Ruth Tobi , Christian Aaron Kobina 
Published: July 2024

Abstract

Background:
Stunting remains a public health concern in sub-Saharan Africa. Despite the evolving awareness of the effect of family composition on child health outcomes, the influence of sibling gender on stunting has seldom been consistent. The current study investigated the association between sibling composition and stunting among children under 5 years in Ghana.
Methods
This cross-sectional study utilized data from the most recent Ghana Demographic and Health Survey (GDHS 2022), focusing on 4412 mother-child dyads. Stunting prevalence was assessed through descriptive analysis, while logistic regression analysis was employed to examine the association between sibling composition and identify other risk factors associated with stunting.
Results
The prevalence of stunting among children under five years of age was 18%. It was observed from the composite and sex-stratified models that having male siblings increased children’s odds of being stunted. Furthermore, being a male child (OR: 1.49; 95% CI: 1.15, 1.94) and belonging to a household with an unimproved water supply (OR: 10.9; 95% CI: 1.03, 1.82) increased children's likelihood of stunting.
Conclusion
This study revealed that the extra nutrients male children require for healthy growth and development may heighten competition for nutrients, especially in resource-constrained households. Parents and guardians are advised to be consciously aware of the subtle and apparent competition between siblings and take appropriate measures to prevent children’s deprivation of nutrition by their male siblings.
Optimizing grassland productivity and sustainability: effects of a legume or N fertiliser application on N cycling
Authors: Borré João , Ramalho Israel , Monteiro Rafael , Souza Wesley , Soares Stallone , Souza Lígia , Alves Bruno , Casagrande Daniel , Homem Bruno , Boddey Robert , Macedo Robert , Urquiaga Segundo 
Published: July 2024

Abstract

The absence of grazing management, coupled with limited N replacement, significantly promotes grassland degradation. Nitrogen input via fertiliser or biological fixation is critical for achieving productive and sustainable grassland systems. This two-year study assessed the N cycling of three pasture types (PTs): 1) mixed Marandu palisadegrass (Urochloa brizantha) and perennial horse gram (Macrotyloma axillare) without N fertiliser (Mixed); 2) monoculture Marandu palisadegrass fertilised with 138 kg N ha− 1 yr− 1 (N-fertilised); and 3) monoculture Marandu palisadegrass without N fertiliser (Unfertilised). Litter responses, forage and N intake, N livestock excretion and N cycling were measured. There were no differences between PTs for the existing litter (an average of 3,485 kg ha− 1; P = 0.204). More N was cycled via litter in the Mixed pasture than N-fertilised and Unfertilised pastures (95.7 vs. 63.6 and 51.8 kg N ha− 1 season− 1; P < 0.001). There was no difference between PTs for the total N excretion per animal (an average of 79.5 g animal d− 1; P = 0.727). However, per hectare, total N excretion in the N-fertilised pasture increased 20.4 and 22.5% than Mixed and Unfertilised pastures, respectively (P = 0.010). In the N-fertilised and Mixed pastures, there was a positive overall change of N in the soil-plant-animal system of 83.5 and 28 kg N ha− 1 year− 1, respectively. In the Unfertilised pasture, there was an overall negative change of N in the soil-plant-animal system of -27 kg N ha− 1 year− 1. Nitrogen application or perennial horse gram integration in a grass pasture increased the conservation of soil N reserves.
Simulating residual stresses formed in the technological sequence of shot-impact treatment–flap-wheel trimming
Authors: Le Tri Vinh , Koltsov V. P. , Starodubtseva D. A. 
Published: July 2024

The paper aims to study the stress-strain state of the surface layer in a VT95 aluminum alloy part during its shot-impact treatment in the sequence of “shot-impact treatment–flap-wheel trimming” operations. The research objects included large parts, such as panels and cladding of complex shapes used in aircraft, missile, and shipbuilding industries. Computer simulation in the Ansys Workbench 19.0 software package was used to develop a methodology for determining residual stresses. As a result of simulating the studied treatment sequence, a visual representation of the residual stress formation pattern, as well as physical values and distribution curves of residual stresses, were obtained. The distribution pattern of residual stresses after performing two types of treatment was established to be similar. The maximum value of residual stresses, obtained as a result of performing a shot-impact treatment of the part surface with a shot of 3.0 mm in diameter at a shot-impact rate of 25 m/s, reaches about 600 MPa at a depth of 1.0 mm. Following the shot-impact treatment, flap-wheel trimming is performed in the finite element simulation as a set of abrasive grains at a rate of 18.316 m/s. The removal of the 25-, 50-, and 75-μm layer from the surface of the plate during trimming contributes to the shearing of the upper part in the residual stress diagram and, as a result, to a decrease in the values of residual stresses in the shot-impact treatment–flap-wheel trimming sequence to 400 MPa. In addition, along with an increase in the thickness of the layer removed from the surface during trimming, the value of residual stresses decreases more slowly. In this case, the thickness of the removed layer causes no effect on the depth of residual compression stresses (about 0.7 mm). The developed finite element model makes it possible to predict and control the level and magnitude of residual stresses in an aluminum alloy sample at the stage of its preparation for both a shot-impact treatment operation and the combination of shotimpact treatment and flap-wheel trimming.
Analysis of approaches to integrating microgrids into energy communities
Authors: Popova E. V. , Tomin N. V. 
Published: July 2024

In this article, we set out to identify and analyze the key features of aggregating microgrids into energy communities, with a focus on the predominance of industrial or residential loads. Research methods included a literature review and meta-analysis in the field of planning, modelling and management of microenergy systems and their communities. In addition, a methodological approach combining multi-criteria decision-making methods and artificial intelligence was used. The efficiency of the approach was demonstrated by the establishment of two types of energy communities for remote settlements on the Sea of Japan coast, which integrated residential and industrial loads. The “Autonomous Operator” model, which involved a two-level optimization and reinforcement learning algorithm based on Monte Carlo tree search, was tested in order to determine the optimal economic management of operation modes of the potential energy community. At the lower level, the problem of finding market equilibrium was solved by minimizing the function of total operating costs. At the upper level, the management strategy that provides the optimal profit distribution among the community members was selected. Two scenarios of microgrid integration and operation in an energy community were studied: industrial and public types. The research demonstrated that operating settlements as energy communities is a more economically and ecologically advantageous approach than operating them individually. The results indicated that the levelized cost of electricity (LCOE) decreased more significantly when combining settlements in an industrial-type energy community (from 22 rub/kWh to 6 rub/kWh) compared to a public-type community (from 22 rub/kWh to 9 rub/kWh). The analysis of the above characteristics of different types of energy communities can help designers to determine the possibilities, features and consequences of aggregating microgrids of different types under various territorial and climatic conditions.
importância da informação em rótulos de produtos da indústria cosmética
Authors: Mota Francisca Rosaline Leite , Pereira Monalisa de Oliveira , Camargo Vanessa Zaclikevic 
Published: July 2024

A oferta e demanda por produtos cruelty free é tema de destaque na contemporaneidade. As informações disponibilizadas nos rótulos de produtos devem ser bussólas a guiar o consumidor na hora da compra. O objetivo da pesquisa foi estudar se o acesso a informações nos rótulos de produtos cosméticos influencia a decisão de compra. A metodologia adotou a pesquisa exploratória com abordagem qualitativa. O universo de pesquisa foi formado por consumidores que adquirem produtos em três grandes redes de atacado e varejo do município de Maceió, capital do estado de Alagoas. A amostra foi aleatória e o instrumento de coleta de dados utilizado foi um Formulário do Google Forms. A coleta dos dados foi realizada no período de outubro a dezembro de 2023 e contou com a participação de 138 participantes. Os resultados mostraram baixo percentual de respondentes (33,6%) que afirmaram realizar a leitura das informações dos rótulos antes de comprar os produtos. 46% dos respondentes afirmaram que dariam preferência ao consumo de produtos que tenham o selo cruelty free e 48% afirmaram que dariam preferência ao consum destes produtos a depender do preço praticado. Os dados revelaram que, mesmo ainda tímida, há uma adesão aos produtos cruelty free.
Unraveling of Potential Targets for Andrographolide, Neoandrographolide and 5-hydroxy, 7-methoxy Flavone in the Treatment of Rheumatoid Arthritis using Network Pharmacology and Molecular Docking
Authors: Rana Neha , Grover Parul , Singh Hridayanand , Rastogi Sameer , Chawla Pooja A. 
Published: July 2024

:
Joint degeneration is a possible outcome of rheumatoid arthritis, an inflammatory disorder that is
chronic, systemic, and progressive. Andrographis paniculata is known to contain many phytoconstituents that
have demonstrated therapeutic effects in terms of inflammation. However, the therapeutic actions of Andrographis paniculata are still not fully understood. The present study aims to better understand rheumatoid
arthritis and its possible treatments through the identification of relevant targets and mechanisms. A total of 47
common targets were identified for andrographolide, while 38 common targets were found for neoandrographolide. Additionally, 53 common targets were discovered for 5-hydroxy-7-methoxy flavone. Furthermore,
a screening process was carried out to identify 9 primary hubb targets for andrographolide, neoandrographolide, and 5-hydroxy-7-methoxy flavone. Twenty useful gene ontology (GO) terms and twenty important
Kyoto Encyclopaedia of Genes and Genomes (KEGG) pathways were found through the study of gene ontology and pathways. Molecular-docking analysis revealed that andrographolide had the highest binding efficacy (-
7.8) towards the Serine/threonine-protein kinase 2 (PIM2) target. On the other hand, neoandrographolide displayed the highest binding efficacy towards mitogen-activated protein kinase (MAPK1) and Interlukine-6 (IL6), with docking scores of (-9.0) and (-7.2), respectively. Furthermore, 5-hydroxy-7-methoxy flavone showed
the highest docking score (-6.6) with Arachidonate 12-lipoxygenase (ALOX-12). The identification of numerous targets linked with various pathways in the treatment of Rheumatoid arthritis proves to be a helpful resource for future investigation into the mechanism and clinical applications of AP, NP, and 5H-flavone.
Chemical Compositions, Antimicrobial and Therapeutic Properties of
Essential Oils of Dennettia Tripetala
Authors: J. Ekandem Joachim , A. Udourioh Godwin , K. Obi Leonard , Solomon Moses M. 
Published: July 2024

Background:
It is well-known that essential oils are a rich source of bioactive components and are traditionally used as one of the alternatives to conventional medicines for treating various diseases and symptoms. Like other natural products, they are safe but should be used with care
since all substances have potential toxicity depending on the conditions of exposure, the dose, and
the route of administration.

Method:
This manuscript studies the chemical composition and antimicrobial properties of essential
oil derived from D. tripetala. The essential oil was extracted from fresh D. tripetala fruits using
steam distillation and subsequently subjected to Fourier Transform Infrared Spectroscopy (FT-IR)
and Gas Chromatography with Flame Ionization detection (GC-FID) analyses. The antimicrobial
potential of the essential oil was evaluated against a panel of microorganisms, namely Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Salmonella typhi, Klebsiella pneumoniae, Pseudomonas aeruginosa, Candida albicans, and Aspergillus niger.

Results:
The GC-FID analysis unveiled a diverse array of compounds within the essential oil, with
the notable constituents being linalool, benzyl nitrile, benzene (2-nitroethyl), bicyclo(4.2.0)octa1,3,5-triene, 1,3,7-Octatrien-5-yne, styrene, butylated hydroxytoluene, and Nerolidol 2. D. tripetala
essential oil significantly inhibits the microbial activities of all the tested organisms. It exhibits inhibitory activity against Bacillus subtilis and Escherichia coli at a MIC value of 12.5%, Staphylococcus
aureus, and Pseudomonas aeruginosa at a MIC value of 25%, Candida albicans at a MIC value of
50%, and Aspergillus niger at MIC value 25%. The strongest inhibition of the oil is against Klebsiella pneumoniae at a MIC value of 3.12%.

Conclusion:
This research posits that the ethnomedicinal value ascribed to the essential oil of D.
tripetala can be attributed to the presence of the identified compounds, some of which are already
recognized for their biological activities. The essential oil presents promising potential as a source of
lead compounds for developing anti-infective drugs, particularly those targeted against Klebsiella
pneumoniae
Exercise Alters FBF1-Regulated Novel-miRNA-1135 Associated with Hydrolethalus Syndrome 1 in Rheumatoid Arthritis: A Preliminary Study
Authors: Tansathitaya Vimolmas , Sarasin Witchana , Phakham Tanapati , Sawaswong Vorthon , Chanchaem Prangwalai , Payungporn Sunchai 
Published: July 2024

Background:
Hydrolethalus Syndrome 1 (HYDS1) is a rare disorder that occurs commonly in Finnish infants but originates from the mother. This autosomal recessive syn-drome is associated with the FBF1, which is usually expressed in the centriole. The FBF1 is an inheritable arthritis disease phenotype that includes rheumatoid arthritis. Several studies have investigated males with FBF1 mutation carriers also related to arthritis diseases, including those under rheumatoid arthritis conditions, which revealed the possibility of conferring the gene mutation to the next generation of offspring. Nonetheless, there are some complications of FBF1 mutation with target miRNAs that can be affected by exercise.

Objective:
The objective of this study was to evaluate the different exercises that can be utilized to suppress the FBF1 mutation targeted by Novel-rno-miRNAs-1135 as a biomarker and assess the effectiveness of exercise in mitigating the FBF1 mutation.

Methods:
Four exercise interventional groups were divided into exercise and non-exercise groups. One hundred microliter pristane-induced arthritis (PIA) was injected at the dorsal re-gion of the tails of rodents and introduced to the two PIA interventional groups. On day forty-five, all animals were euthanized, and total RNA was extracted from the blood samples of ro-dents, while polymerase chain reaction (PCR) was amplified by using 5-7 primers. Computeri-zation was used for miRNA regulation and analysis of target gene candidates.

Results:
The novel-rno-miRNA-1135 was downregulated to FBF1 in exercise groups. The exercise was found to have no significant impact in terms of change in novel-rno-miRNA-1135 regulation of FBF1 expression.

Conclusion:
Exercise has no impact on novel-rno-miRNA-1135 targeted for FBF1 in autoso-mal recessive disease.
ANALYSIS OF METACHRONOUS MALIGNANT DISEASES IN BREAST CANCER PATIENTS
Authors: Kostelei S. V. , Kysylytsia O. V. , Vytrykhovska I. V. , Drin I. T. , Hrytsyk R. A. , Dyakiv I. B. 
Published: June 2024

Рак грудної залози (РГЗ) посідає перше місце серед усіх злоякісних новоутворень жіночого населення.
Міжнародне агентство ВООЗ із дослідження раку (IARC) прогнозує до 2050 року значне збільшення захворюваності на рак і подвоєння летальних випадків.
У структурах злоякісних новоутворень полінеоплазії займають у середньому 2,47%, і їхня частка продовжує зростати. Серед жінок найбільш уразливою до первинно-множинних злоякісних пухлин є репродуктивна система. Найчастіше спостерігаємо поєднання гормонально-залежних утворень (раку грудної залози (РГЗ), тіла матки (РТМ) і яйників (РЯ)) із раком товстої кишки (РТК) та шлунка (РШ)). Вагомий вплив на це явище мають хвороби цивілізації.
Мета дослідження. Проаналізувати метахронні неоплазії в пацієнток на рак грудної залози.
Матеріали і методи. Ретроспективно досліджено 73 пацієнтки з метахронними полінеоплазіями, які лікувалися в КНП “ПКОЦ ІФ ОР” із 2019 по 2023.
Результати. У структурі пацієнток на первинно-множинний РГЗ переважали працездатні жінки (50-59 років) з метахронними РТМ, РЯ, РТК чи РШ (44%). Рак тіла матки й товстої кишки здебільшого діагностували через 10 років (33,33% і 52,17% відповідно), рак шлунка – упродовж року (40%), а рак яйника – за 5 років (50%). Згадані метахронні пухлини здебільшого виникали в пацієнток на первинно-діагностований РГЗ ІІА-ІІВ стадії. РТМ і РЯ найчастіше асоціюються з люмінальним В типом РГЗ (38,89% і 57,14% відповідно), а РТК – з люмінальним А (44,45%). РШ однаково пов’язаний з люмінальним В і Her2/neu-позитивним підтипами (по 50%).
Висновки. Необхідне надалі вивчення взаємозв’язку між раком грудної залози та метахронними раками тіла матки, яйника, товстої кишки й шлунка. Отримані знання варто спрямувати на покращення програм скринінгу та ранньої діагностики раку грудної залози й полінеоплазій. Беручи до уваги всі ключові фактори, варто спробувати розробити алгортм підрахунку ризику метахронних пухлин у пацієнток на первиннодіагностований рак грудної залози.
FEATURES OF STRUCTURAL CHANGES OF THE THYROID GLAND IN PATIENTS WITH TYPE 2 DIABETES AND DIABETIC KIDNEY DISEASE
Authors: Vereshchynska A. P. , Urbanovych A. M. 
Published: June 2024

Цукровий діабет 2 типу (ЦД2) - це метаболічне захворювання, яке характеризується системними ураженнями та призводить до хронічних ускладнень. Одним з поширених мікросудинних ускладнень ЦД2 є діабетична хвороба нирок (ДХН). Захворювання щитоподібної залози (ЩЗ) та ЦД2 взаємопов’язані та двонаправлені ендокринні розлади. Пацієнти із ЦД2 можуть мати різноманітні структурні зміни в ЩЗ, що вимагають оцінки за допомогою ультразвукового дослідження (УЗД). Крім того, зміни функціонального стану нирок прямо впливають на роботу ЩЗ, проте немає достатньо інформації про взаємозв’язок саме ДХН та морфологічних змін ЩЗ.
Мета - дослідити особливості структурних змін ЩЗ у пацієнтів із ЦД2 та ДХН.
Матеріали і методи. У дослідженні взяло участь 125 пацієнтів із ЦД2 та ДХН, які перебували на стаціонарному лікуванні у ЛОДКЛДЕЦ в період з лютого 2022 р. по квітень 2023 р. Відповідно до ступеня ризику прогресування ДХН сформовано 4 групи, та проведено УЗД ЩЗ з метою обчислення об’єму та оцінки структури залози. Статистичні порівняння проводили за допомогою t-тестів незалежних вибірок для даних із нормальним розподілом і χ2-тестів для відсотків.
Результати. Виявлено збільшення об’єму ЩЗ відповідно до стадії прогресування ДХН (17,24±4,01, 18,36±30, 20,06±4,21 см3, р < 0,05). Доведено пряму кореляцію між ІМТ та об’ємом ЩЗ (r = 0,013; 0,137 та 0,85 відповідно до груп). Спостерігався позитивний кореляційний зв’язок у всі групах між креатиніном та об’ємом ЩЗ (r = 0,094; 0,372; 0,045, p < 0,01), а також між САК й об’ємом ЩЗ (r = 0,004; 0,097; 0,552, p < 0,01 відповідно). Крім того було відзначено негативний кореляційний зв’язок між рШКФ та об’ємом ЩЗ (r=-0,278; -0,351; -0,362; р<0,01). Підтверджено прямий вплив збільшення рівня ТТГ на об’єм ЩЗ (r = 0,291; 0,231; 0,245, <0,05) у всіх групах відповідно. Частка пацієнтів із вузловими утвореннями ЩЗ становила (36,8%, 51,5%, 68,8%, р < 0,05) та з ознаками АІТ (22,4 %, 18,2 %, 31,2%) у всіх групах відповідно.
Висновки. У пацієнтів із ЦД2 відповідно до ризику прогресування ДХН вірогідно збільшувався об’єм й поширеність вузлів ЩЗ, тоді як частота виявлення ознак АІТ була незначною.
An Integrated Approach towards Conservation of Traditional Patterns in Chinese Traditional Villages: A systematic literature review
Authors: Gao Lihui , Mohd. Ariffin Noor Fazamimah , Hussein Mohd Kher , Liu Shan , Wang Beibei 
Published: June 2024

In recent years, the Chinese government and the local government have issued many conservation documents for traditional villages. However, the conservation of traditional patterns has still not been significantly improved. Therefore, this paper explores the conservation approaches of traditional patterns in traditional villages with a systematic literature review. The study suggests that adopting necessary conservation and safeguarding measures, harmonizing conflicts between policies and legislation, improving public participation measures in local communities, and formulating adaptive utilization can promote the conservation and development of traditional patterns of traditional villages.
Architectural Intelligence (ArcAI) Evolution and Progress on Sustainable Smartscapes Planning for the Cities of Tomorrow
Authors: Aziz Salmiah , Sharun Siti Maryam , Wagiman Khairul Rijal , Chumporn Moorapun  
Published: June 2024

Rapid urbanization and environmental concerns underscore the need for sustainable design in urban areas. This study delves into sustainable smart scapes, integrating eco-friendly practices and smart technologies to meet urban demands. It examines green infrastructure, renewable energy, and smart parameters’ integration, assessing their effectiveness through literature review and case studies. Exploring technologies like Internet of Things (IoT), artificial intelligence (AI), and data analytics, the research adopts qualitative methods - case studies, structured interviews, and literature review – for a nuance understanding of. It aims to inform future sustainable architecture and urban planning, emphasizing smartscapes’ role in resource optimization, economic growth, and community inclusivity, contributing to interdisciplinary knowledge advancement.