bluuebunny/crossref_metadata_2025_split huggingface dataset:
Political challenges and economic cooperation: The legacy of the 1930s USSR–Turkey economic relations and the contemporary economic context of Russia–Turkey
Authors: Deniz Önder 
Published: July 2024

AbstractIn the early 20th century, the emergence of the Soviet Union and Turkey in the political arena led to the end of Russo‐Turkish conflicts and the formation of bilateral relations. In the 1920s, the political cooperation that commenced between the Union of Soviet Socialist Republics (USSR) and Turkey transformed into economic solidarity. The 5‐year plans of the USSR and the financial support and technical knowledge it provided to Turkey significantly contributed to Turkey's industrialisation process. After World War II, political and economic dynamics changed, leading to a decline in these relations. Following the dissolution of the USSR, relations between Turkey and the Russian Federation revived and economic cooperation increased. This collaboration, particularly evident in the tourism, energy, and trade sectors, has intensified. This article analyses the contributions of the 1930s USSR–Turkey cooperation to Turkey's industrialisation process and its contemporary effects. Additionally, it highlights a positive public and political approach in Turkey towards its economic relations with Russia.
Plumbagin ameliorates LPS‐induced acute lung injury by regulating PI3K/AKT/mTOR and Keap1‐Nrf2/HO‐1 signalling pathways
Authors: Liu Zhengjia , Wei Jiahui , Sun Hongbin , Xu Lei 
Published: July 2024

AbstractAcute lung injury (ALI) is a major pathophysiological problem characterized by severe inflammation, resulting in high morbidity and mortality. Plumbagin (PL), a major bioactive constituent extracted from the traditional Chinese herb Plumbago zeylanica, has been shown to possess anti‐inflammatory and antioxidant pharmacological activities. However, its protective effect on ALI has not been extensively studied. The objective of this study was to investigate the protective effect of PL against ALI induced by LPS and to elucidate its possible mechanisms both in vivo and in vitro. PL treatment significantly inhibited pathological injury, MPO activity, and the wet/dry ratio in lung tissues, and decreased the levels of inflammatory cells and inflammatory cytokines TNF‐α, IL‐1β, IL‐6 in BALF induced by LPS. In addition, PL inhibited the activation of the PI3K/AKT/mTOR signalling pathway, increased the activity of antioxidant enzymes CAT, SOD, GSH and activated the Keap1/Nrf2/HO‐1 signalling pathway during ALI induced by LPS. To further assess the association between the inhibitory effects of PL on ALI and the PI3K/AKT/mTOR and Keap1/Nrf2/HO‐1 signalling, we pretreated RAW264.7 cells with 740Y‐P and ML385. The results showed that the activation of PI3K/AKT/mTOR signalling reversed the protective effect of PL on inflammatory response induced by LPS. Moreover, the inhibitory effects of PL on the production of inflammatory cytokines induced by LPS also inhibited by downregulating Keap1/Nrf2/HO‐1 signalling. In conclusion, the results indicate that the PL ameliorate LPS‐induced ALI by regulating the PI3K/AKT/mTOR and Keap1‐Nrf2/HO‐1 signalling, which may provide a novel therapeutic perspective for PL in inhibiting ALI.
Sarcopenia and survival in colorectal cancer without distant metastasis: a systematic review and meta‐analysis
Authors: Lin Wen‐Li , Nguyen Thi‐Hoang‐Yen , Huang Wen‐Tsung , Guo How‐Ran , Wu Li‐Min 
Published: July 2024

AbstractBackground and AimDespite prior attempts to evaluate the effects of sarcopenia on survival among patients with colorectal cancer (CRC), the results of these studies have not been consistent. The present study aimed to evaluate the association between sarcopenia and survival among patients having CRC without distant metastasis by aggregating multiple studies.MethodsWe performed a literature search using computerized databases and identified additional studies from among the bibliographies of retrieved articles. The quality of each study was evaluated using the Newcastle–Ottawa Scale, and meta‐analyses were performed to evaluate overall survival (OS) and disease‐free survival (DFS).ResultsThirteen studies with up to 6600 participants were included in the meta‐analyses, with a mean age of 63.6 years (range: 18–93 years). We found that preoperative sarcopenia was associated with worse OS (hazard ratio [HR]: 1.61; 95% confidence interval [CI]: 1.38–1.88) and worse DFS (HR: 1.57; 95% CI: 1.10–2.24). Compared with patients without sarcopenia after tumor resection, those with postoperative sarcopenia had worse OS (HR: 1.76; 95% CI: 1.47–2.10) and DFS (HR: 1.79; 95% CI: 1.46–2.20).ConclusionThese meta‐analyses suggest that sarcopenia, no matter observed before or after tumor resection, is associated with worse OS and DFS in patients with CRC who have no distant metastasis.
Revitalizing skin, hair, nails, and muscles: Unlocking beauty and wellness with vegan collagen
Authors: Warma Samrat , Warma Himanshi , Merja Apeksha , Patel Nayan , Patel Maheshvari 
Published: July 2024

AbstractBackgroundCollagen, a key protein in the body maintains hair, skin and bone health and its production tends to decrease in synthesis as humans age. The demand for vegan collagen‐builder has increased worldwide due to increased adaptability to vegan diet.ObjectiveThis clinical study was designed aim to evaluate the safety and efficacy of vegan collagen builder (VEGCOL™️) at different dosages (2.5, 5, and 10 g) in adult participants.MethodsTotal 66 subjects (22 subjects/dose) aged 30 to 50 years were enrolled, and 63 subjects completed the study. Duration of study was 60 days. Evaluations included change in skin elasticity, hydration, crow's feet area wrinkles, fine lines, skin, Glogau skin age, change in pain scale score, muscle strength and subject perception assessment about test treatment use.ResultsAfter 60 days of treatment, there was significant improvement in hair growth rate by 45.01%, 38.54% and 50.37% with p < 0.01 for doses 2.5, 5, and 10 g respectively. Additionally, 19.64% (p < 0.0001) and 20.51% (p < 0.0001) increase in hair density and hair thickness respectively was observed with 10 g dose. 2.5 g dose resulted in 33.03% (p < 0.01) increase in skin smoothness and 49.94% (p < 0.0001) decrease in crow's feet area wrinkles, decreased retraction time by 21.71 milliseconds (p < 0.05). 52.54% reduction in pain score (p < 0.001). No any adverse events were reported.ConclusionVegan collagen‐builder effectively improved multiple age‐related concerns such as wrinkles, fine lines, joint pain, muscle strength and hair growth. All respondents perceived the product as beneficial in improving the aesthetics of the skin, hair, and nails. The findings support the use of vegan collagen‐builder as safe and efficacious in promoting healthier skin, stronger muscles, and improved hair and nail conditions.
Comparative study between the efficacy of prabotulinum toxin‐A versus onabotulinum toxin‐A for the treatment of upper facial expression lines
Authors: Rodriguez‐Chavez Nicte , Gonzalez‐Mondragón Edric , Nava‐Castañeda Angel 
Published: July 2024

AbstractBackgroundBotulinum Toxin (BoNTA) is the most used nonsurgical aesthetic procedure to treat facial expression lines.AimsThis study compared the efficacy of Prabotulinum toxin‐A, a novel BoNTA that originates from Clostridium botulinum Hall‐A, with onabotulinum toxin‐A in treating facial expression lines using the Facial Wrinkle Scale (FWS) and FACE‐Q questionnaires.MethodsThis was an experimental, comparative, longitudinal, open‐label, and prospective study. Patients aged between 25 and 40 years with upper‐third facial expression lines were included. Follow‐ups were made at three, seven, 30, and 120 days.ResultsA total of 26 patients were included: 20 female, and six males, with a mean age of 28.26 years. An average of 31.00 IU and 31.38 IU were administered to the onabotulinum and prabotulinum groups, respectively. The prabotulinum group demonstrated superiority in FWS and Face‐Q scores between the first and third days (p ≤ 0.001, p < 0.001, respectively), which continued on day 7. By day 30, there were no differences in the scores of the two questionnaires.ConclusionsPrabotulinum toxin‐A is a safe and effective treatment for upper‐third facial wrinkles. On day three and seven, the results suggest that prabotulinum toxin‐A has a quicker onset of action than onabotulinum toxin‐A. On days 30 and 120, both groups showed similar FWS and Face‐Q scores.
The uneven impact of Medicaid expansion on rural and urban Black, Latino/a, and White mortality
Authors: Mueller J. Tom , Baker Regina S. , Brooks Matthew M. 
Published: July 2024

AbstractPurposeTo determine the differential impact of Medicaid expansion on all‐cause mortality between Black, Latino/a, and White populations in rural and urban areas, and assess how expansion impacted mortality disparities between these groups.MethodsWe employ a county‐level time‐varying heterogenous treatment effects difference‐in‐difference analysis of Medicaid expansion on all‐cause age‐adjusted mortality for those 64 years of age or younger from 2009 to 2019. For all counties within the 50 US States and the District of Columbia, we use restricted‐access vital statistics data to estimate Average Treatment Effect on the Treated (ATET) for all combinations of racial and ethnic group (Black, Latino/a, White), rurality (rural, urban), and sex. We then assess aggregate ATET, as well as how the ATET changed as time from expansion increased.FindingsMedicaid expansion led to a reduction in all‐cause age‐adjusted mortality for urban Black populations, but not rural Black populations. Urban White populations experienced mixed effects dependent on years after expansion. Latino/a populations saw no appreciable impact. While no effect was observed for rural Black and Latino/a populations, rural White all‐cause age‐adjusted mortality unexpectedly increased due to Medicaid expansion. These effects reduced rural‐ and urban‐specific Black‐White mortality disparities but did not shrink the rural‐urban mortality gap.ConclusionsThe mortality‐reducing impact of Medicaid expansion has been uneven across racial and ethnic groups and rural‐urban status; suggesting that many populations—particularly rural individuals—are not seeing the same benefits as others. It is imperative that states work to ensure Medicaid expansion is being appropriately implemented in rural areas.
The perils of methods that detect lies 70% of the time: A reply to Ben‐Shakhar and Verschuere (2024)
Authors: Brennen Tim , Magnussen Svein 
Published: July 2024

AbstractBen‐Shakhar and Verschuere (2024) commented on Brennen and Magnussen's (2023) review of the literature on lie detection. They argued that the review's conclusion that such methods are not ready for forensic use is too pessimistic and that they already are in use worldwide. While we agree that many jurisdictions do in fact use such methods, we see this as cause for alarm rather than confirmation of their utility. It is documented that several lie detection methods distinguish to a statistically significant degree between deceitful and truthful statements, but they also have substantial error rates. This means that applying them at the level of the individual statement will frequently be misleading, making them unsuited to guiding police investigations.
Impact of the restraint decision tree for physical restraint use in South Korean neurointensive care units
Authors: Kang Jaejin , Kim Sol , Lee Minji , Na Hyunjoo 
Published: July 2024

AbstractBackgroundNurses in neurointensive care units (NCUs) commonly use physical restraint (PR) to prevent adverse events like unplanned removal of devices (URDs) or falls. However, PR use should be based on evidenced decisions as it has drawbacks. Unfortunately, there is a lack of research‐based PR protocol to support decision‐making for nurses, especially for neurocritical patients.AimThis study developed a restraint decision tree for neurocritical patients (RDT‐N) to assist nurses in making PR decisions. We assessed its effectiveness in reducing PR use and adverse events.Study DesignThis study employed a baseline and post‐intervention test design at a NCU with 19 beds and 45 nurses in a tertiary hospital in a metropolitan city in South Korea. Two‐hundred and thirty‐seven adult patients were admitted during the study period. During the intervention, nurses were trained on the RDT‐N. PR use and adverse events between the baseline and post‐intervention periods were compared.ResultsPost‐intervention, total number of restrained patients decreased (20.7%–16.3%; χ2 = 7.68, p = .006), and the average number of PR applied per restrained patient decreased (2.42–1.71; t = 5.74, p < .001). The most frequently used PR type changed from extremity cuff to mitten (χ2 = 397.62, p < .001). No falls occurred during the study periods. On the other hand, URDs at baseline were 18.67 cases per 1000 patient days in the high‐risk group and 5.78 cases per 1000 patient days in the moderate‐risk group; however, no URD cases were reported post‐intervention.ConclusionsThe RDT‐N effectively reduced PR use and adverse events. Its application can enhance patient‐centred care based on individual condition and potential risks in NCUs.Relevance to Clinical PracticeNurses can use the RDT‐N to assess the need for PR in caring for neurocritical patients, reducing PR use and adverse events.
Automated software‐derived supine baseline impedance is highly correlated with manual nocturnal baseline impedance for the diagnosis of GERD
Authors: Reddy Alexander T. , Patel Amit , Leiman David A. 
Published: July 2024

AbstractBackgroundMean nocturnal baseline impedance (MNBI) can improve diagnostic accuracy for gastroesophageal reflux disease (GERD), but must be manually calculated and is not routinely reported. We aimed to determine how automated software‐derived mean supine baseline impedance (MSBI), a potential novel GERD metric, is related to MNBI.MethodsConsecutively obtained pH‐impedance studies were assessed. Manually extracted MNBI was compared to MSBI using paired t‐test and Spearman's correlations.Key ResultsThe correlation between MNBI and MSBI was very high (ρ = 0.966, p < 0.01).Conclusions & InferencesThe ease of acquisition and correlation with MNBI warrant the routine clinical use and reporting of MSBI with pH‐impedance studies.
Swallowing outcomes after transoral robotic surgery and adjuvant treatment in unknown primary
Authors: van der Scheer Fennetta A. , Jansen Femke , Eerenstein Simone E. J. , Vergeer Marije R. , Leemans C. René , Verdonck‐de Leeuw Irma M. , Hendrickx Jan‐Jaap 
Published: July 2024

AbstractObjectivesRobotic transoral mucosectomy of the base of tongue was introduced as a diagnostic procedure in patients treated for head and neck cancer with unknown primary (CUP), increasing the identification rate of the primary tumour. For the treatment of CUP, a considerable percentage of patients require adjuvant (chemo)radiation. The aim of this study was to investigate swallowing outcomes among CUP patients after TORS and adjuvant treatment.Subjects and MethodsA systematic review was carried out on studies investigating the impact of TORS and adjuvant treatment on swallowing‐related outcomes among CUP patients In addition, a cross‐sectional study was carried out on swallowing problems (measured using the SWAL‐QOL questionnaire) among CUP patients in routine care who visited the outpatient clinic 1–5 years after TORS and adjuvant treatment.ResultsThe systematic review (6 studies; n = 98) showed that most patients returned to a full oral diet. The cross‐sectional study (n = 12) showed that all patients were able to return to a full oral diet, nevertheless, 50% reported swallowing problems in daily life (SWAL‐QOL total score ≥14).ConclusionAlthough after TORS and adjuvant treatment for CUP a full oral diet can be resumed, patients still experience problems with eating and drinking in daily life.
BLOWING IN THE WIND: THE SEASONALITY OF FORAGING IN LATE BRONZE AGE CRETE
Authors: Moody Jennifer 
Published: July 2024

SummaryMost foraging, especially for wild edible plants, is a seasonal occupation, impacted by weather in the short term and climate change in the long term. In Crete today, foraging not only supplements the diet but is a valued inter‐generational social activity. Foraging activities are not directly mentioned in the Late Bronze Age Linear B tablets from Crete, suggesting that most were the purview of non‐elites. Here I present evidence for changes in seasonality during the Late Bronze Age and its possible impact on plant foraging. The Linear B and archaeological evidence for foraging activity and its relationship to elites and non‐elites is also discussed.
HOW ELITIST WERE TYPICAL MYCENAEAN COMMUNITIES? INVESTIGATING RELATIVE STATUS IN MYCENAEAN DAMOI THROUGH THE LANDHOLDERS OF THE PYLOS EP AND EA SERIES
Authors: Lupack Susan 
Published: July 2024

SummaryAlthough traditionally the focus of Mycenaean studies has been the elite and the administrative centres referred to as ‘palaces’, nonetheless academics investigating Mycenaean society have increasingly turned their attention to nonpalatial sectors of society. This article investigates the different levels of society that are recorded within two Linear B land tenure series, specifically the Ep and Ea series. The Ep tablets record the landholdings of the inhabitants of pa‐ki‐ja‐ne, a damos that was home to Pylos's most significant sanctuary. A steep hierarchy is demonstrated for its inhabitants by the relative sizes of their landholdings, with prominent religious personnel among those at the top and many ‘servants of the deity’ at the bottom. The Ea damos, in contrast, differs in the professional titles of the landholders—craftsmen and animal herders are prevalent—and in the relative sizes of the landholdings: the Ea series records plots of land that were more equitably sized and generally larger than those of pa‐ki‐ja‐ne. The Ea series can likely be considered as more representative of Mycenaean damoi than pa‐ki‐ja‐ne, which could indicate that the social structure of typical Mycenaean communities was not steeply hierarchical, and perhaps more egalitarian than may have been thought.
Transferability of Effective Consultation Skills for Decision‐Making Support in the Voluntary Surrender of Older Adult Drivers' Licences in Super‐Aged Japan
Authors: Miyoshi Yoko , Yoshioka Shin‐ichi , Yamamoto Miwa 
Published: July 2024

ABSTRACTIntroductionPreviously, we identified eight effective consultation skills to support decision‐making in the voluntary surrender of older adult drivers' licences in super‐aged Japan. This study aimed to clarify the transferability of these skills.MethodsWe collected text data by interviewing 11 safe‐driving counsellors (four police officers, four clerical staff and three nurses) in the License Division of the National Police Agency from February to March 2022. Interviews were semi‐structured and conducted by telephone or email. During the interview, participants were asked to recall their experiences as counsellors providing decision‐making support to older drivers and to compare their experiences with the eight consultation skills. We analysed the content of the responses by quantitative text analysis with KH Coder 3 software.ResultsAs a characteristic of the words and phrases used by counsellors in their narratives about consultation skills, the most frequently extracted words from among 3147 words were think, parties and family, and promote had the highest mediation centrality. The eight subgraphs were ‘Respecting the will of relevant parties from their standpoint is natural’, ‘Listening attentively and empathetically to relevant parties is effective’, ‘Presenting objective data to guide decisions is successful’, ‘Showing cognitive functioning test results is often effective’, ‘Counselors with medical expertise can elicit positive counseling outcomes’, ‘Intervention by medical or police counselors facilitates the decision to surrender voluntarily’, ‘Counseling skills need to be improved’ and ‘A diagram of the 8 skills is helpful for inexperienced counselors’.ConclusionThe results suggest that the eight consultation skills have similarities and are transferable. This transferability might contribute to practical application or cohort follow‐up study research. These skills can be incorporated into counsellor training, and counsellors can be expected to use these skills in the future. Regardless of the safe‐driving counsellor's years of experience, the skills can help them provide uniform and accurate support in decision‐making regarding the voluntary surrender of older adult drivers' licences. These skills are a promising approach to help older adults lead safe and secure lives as they age.
Biplane Reduction: A Novel Technique for Restoring Fibula Length in Maisonneuve Fracture
Authors: Zhong Qigang , Yang Hu , Huai Chaoyue , Yao Yunfeng , Xie Yang , Zhan Junfeng 
Published: July 2024

ObjectiveFibular length is important for ankle stability. Failure to adequately restore and stabilize fibula length may result in malunion, hindering postoperative functional exercises and recovery of ankle function. However, there is no unified and effective reduction method for fibular shortening in Maisonneuve fractures. In this study, we introduce the biplane reduction as an effective surgical technique for restoring the length of the fibula in Maisonneuve fractures.MethodsThis retrospective study enrolled 12 patients preoperatively diagnosed with Maisonneuve fractures between June 2019 and June 2022. All patients underwent our biplane reduction technique to restore the length of their fibula. Operation time, hospital stay, complications, FTA (the angle between the fibular tip and the superior articular surface of the talus), visual analog pain score, and the American Orthopaedic Foot and Ankle Society ankle‐hindfoot score were recorded. An independent sample t‐test was used for component comparisons, and a paired sample t‐test or one‐way analysis of variance was used for intra‐group comparisons.ResultsNo patient was lost to follow‐up and no obvious postoperative complications were observed. After operation, FTA recovered from 37.52 ± 0.37 ° to 40.42 ± 0.43 °, which was significantly improved compared with that before operation (p < 0.01). At the last follow‐up, both the VAS and AOFAS scores showed significant improvement compared to pre‐surgery scores.ConclusionsThe reduction technique proposed in this study to restore the length of the fibula in Maisonneuve fractures is simple and effective, does not require special equipment, and has the advantage of directly examining the reduction condition.