bluuebunny/crossref_metadata_2025_split huggingface dataset:
Expression and role of the genes involved in the transport of bile acids in the liver and kidneys in mice
Authors: Attakpa Eugène S. , Djibril Naguibou M. , Baba-Moussa Farid , Yessoufou Ganiou , Sezan Alphonse 
Published: February 2013

Abstract

Background: Bile acids are synthesized in the liver from cholesterol.

Methods: This study investigated the impact and expression of different carriers of bile acid in the liver and kidneys. Eight-week-old male mice were used, which were fed for 15 days and divided into two groups: 15 mice fed with standard diet (control group) and another 15 mice fed with a rich diet of 5% cholesterol (second group). Bile acid dosage was based on their oxidation by 7α hydroxyl-steroid dehydrogenize. The mRNA expression was quantitatively analyzed by the real time of polymerase chain reaction (RT-PCR), and the expression of the renal carrier bile acid protein was analyzed by Western blot.

Results and conclusions: The expression of bile salt export pump involved in the uptake of bile acids in the basolateral membrane of hepatocytes revealed no differences between the two groups of mice. However, the expression of multidrug resistance-associated protein 2 was reduced in mice of the second group. Moreover, the expressions of organic anion transporting polypeptide 4, organic anion transporting polypeptide 1, and sodium taurocholate co-transporting polypeptide (Ntcp) involved in the uptake of bile acids in the apical pole of hepatocytes are suppressed in mice of the second group. The expression of multidrug resistance-associated protein 3 involved in the secretion of bile acids in the apical membrane of hepatocytes revealed no significant differences between the two groups. In mice of the second group, blood concentration of bile acids on the last day was increased. In those mice, the expression of intestinal bile acid transporter was reduced in the kidneys compared with the control mice.
Evaluation of Metallurgical Quality of Master Heat IN-713C Nickel Alloy Ingots
Authors: Binczyk F. , Cwajna J. , Roskosz S. , Gradoń P. 
Published: February 2013

Abstract
The paper presents the results of evaluation of the metallurgical quality of master heat ingots and of the identification of non-metallic inclusions (oxides of Al., Zr, Hf, Cr, etc.), which have been found in the shrinkage cavities formed in these ingots. The inclusions penetrate into the liquid alloy, and on pouring of mould are transferred to the casting, especially when the filtering system is not sufficiently effective. The specific nature of the melting process of nickel and cobalt alloys, carried out in vacuum induction furnaces, excludes the possibility of alloy refining and slag removal from the melt surface. Therefore, to improve the quality of castings (parts of aircraft engines), it is so important to evaluate the quality of ingots before charging them into the crucible of an induction furnace. It has been proved that one of the methods for rapid quality evaluation is an ATD analysis of the sample solidification process, where samples are taken from different areas of the master heat ingot. The evaluation is based on a set of parameters plotted on the graph of the dT/dt derivative curve during the last stage of the solidification process in a range from TEut to Tsol.
Definition of Alloy Substitute Thermal Capacity Using the Simple Macrosegregation Models
Authors: Mochnacki B. 
Published: February 2013

Abstract
Mathematical description of alloys solidification in a macro scale can be formulated using the one domain method (fixed domain approach). The energy equation corresponding to this model contains the parameter called a substitute thermal capacity (STC). The analytical form of STC results from the assumption concerning the course of the function fS = fS (T) describing the changes of solid state volumetric fraction and the temperature at the point considered. Between border temperatures TS , TL the function fS changes from 1 to 0. In this paper the volumetric fraction fS (more precisely fL = 1- fS ) is found using the simple models of macrosegregation (the lever arm rule, the Scheil model). In this way one obtains the formulas determining the course of STC resulting from the certain physical considerations and this approach seems to be closer to the real course of thermal processes proceeding in domain of solidifying alloy.
Effect of Multipoint Sequential Water Mist Cooling of Casting Die on Microstructure and Mechanical Properties of AlSi11 Alloy
Authors: Władysiak R. 
Published: February 2013

Abstract
The work is a continuation of research on the use of water mist cooling in order to increase efficiency of the die-casting process for aluminum alloys. The paper describes the multipoint sequential cooling system of the casting die and its computer control and monitoring. It also includes results of the tests and analysis of cooling methods during making of the casting. These methods differ from each other in the sequence of casting die cooling and cause effective changes in microstructure and mechanical properties of castings made of AlSi11 alloy. The study demonstrated that the use of multipoint sequential cooling with water mist affects the microstructure refinement and reduces the segregation in the cast as well as more than by 20% increases the mechanical properties of castings in the rough state. The study also demonstrates that the sequential cooling of casting die accelerates the cooling of the casting and shortens die-casting cycle.
Modeling of Two-Stage Solidification: Part I Model Development
Authors: Wodo O. , Gawrońska E. 
Published: February 2013

Abstract
The paper presents a new numerical model of solidification processes in hypoeutectic alloys. The model combines stochastic elements, such as e.g. random nucleation sites and orientation of dendritic grains, as well as deterministic methods e.g. to compute velocity of dendritic tips and eutectic grains. The model can be used to determine the temperature and the size of structure constituents (of both, the primary solid phase and eutectics) and the arrangement of individual dendritic and eutectic grains in the consecutive stages of solidification. Two eutectic transformation modes, typical to modified and unmodified hypoeutectic alloys, have been included in the model. To achieve this, cellular automata and Voronoi diagrams have been utilized.
Thermodynamic Analysis of Cast Irons Solidification With Various Types of Graphite
Authors: Elbel T. , Hampl J. 
Published: February 2013

Abstract
The contribution summarises the results of oxygen activity determinations, which were measured and registered continuously in castings from cast irons with various types of graphite. The results were used to find the relationship between two variables: natural logarithm of oxygen activities and reverse value of thermodynamic temperature 1 /T. Obtained regression lines were used to calculate oxygen activity at different temperatures, to calculate Gibbs free energy ΔG at the different temperatures and to calculate the single ΔG value for significant temperature of the graphite solidification. The results were processed by a statistical analysis of data files for the different types of graphite with flake, vermicular and spheroidal graphite. Each material has its proper typical oxygen activities range and individual temperature function of Gibbs free energy for analysing and governing casting quality.
Application of Time-series Analysis in Control of Chemical Composition of Grey Cast Iron
Authors: Perzyk M. , Rodziewicz A. 
Published: February 2013

Abstract
The aim of the paper was an attempt at applying the time-series analysis to the control of the melting process of grey cast iron in production conditions. The production data were collected in one of Polish foundries in the form of spectrometer printouts. The quality of the alloy was controlled by its chemical composition in about 0.5 hour time intervals. The procedure of preparation of the industrial data is presented, including OCR-based method of transformation to the electronic numerical format as well as generation of records related to particular weekdays. The computations for time-series analysis were made using the author’s own software having a wide range of capabilities, including detection of important periodicity in data as well as regression modeling of the residual data, i.e. the values obtained after subtraction of general trend, trend of variability amplitude and the periodical component. The most interesting results of the analysis include: significant 2-measurements periodicity of percentages of all components, significance 7-day periodicity of silicon content measured at the end of a day and the relatively good prediction accuracy obtained without modeling of residual data for various types of expected values. Some practical conclusions have been formulated, related to possible improvements in the melting process control procedures as well as more general tips concerning applications of time-series analysis in foundry production.
Determination of the Overheating Degree of Moulding Sand with Bentonite - on the Grounds of Simulation Investigations
Authors: Żymankowska-Kumon S. , Holtzer M. , Lelito J. , Dańko R. 
Published: February 2013

Abstract
A determination of the heating degree of the moulding sand with bentonite on the grounds of simulating investigations with the application of the MAGMA program, constitutes the contents of the paper. To this end the numerical simulation of the temperature distribution in the virtual casting mould was performed. It was assumed that the mould cavity was filled with a moulding sand with bentonite of a moisture content 3,2 % and bentonite content 8 %. A computer simulation can be used for predicting the heating degree of moulding sands with bentonite. Thus, prediction of the active bentonite (montmorillonite) content in individual layers of the overheated moulding sand can be done by means of the simulation. An overheating degree of a moulding sand with bentonite, and thus the bentonite deactivation depends on a temperature of a casting alloy, casting mass, ratio of: mass : masscasting, moulding sand amount in the mould and contact area: metal - mould (geometry of the casting shape). Generally it can be stated, that the bentonite deactivation degree depends on two main factors: temperature of moulding sand heating and time of its operation.
Gender Differences in Prosodic Characteristics of Speech in the Task of Serial Subtracting of Sevens
Authors: Nešić Milkica , Čičević Svetlana , Nešić Vladimir , Kostić Jelena , Ćirić Milan 
Published: February 2013

Summary
Significant differences in speech between genders are contained in nonsegmental correlates, i.e. in the prosody and paralinguistics. Pronunciation differences between genders are more numerous than those in grammatical form. This study aims to detect temporal prosodic patterns and investigate gender differences in performing serial sevens subtraction (SSS). One hundred students of medicine (equal number of males and females) voluntarily participated in the investigation. SSS was performed by asking the participant to perform mental arithmetic consisting of repeatedly subtractions of sevens, beginning from one thousand. The students had to pronounce aloud and simultaneously write the results for five minutes. The original program for the analysis of digital signals (ADS) converted the speech signal samples into digital data. MANOVA showed significant gender differences for a group of characteristics of the SSS test: F (11, 75)=4.06, p=0.000. The number of samples per each minute and the total number of samples during five minutes was higher in males compared to females. The average length of articulation of three-digit numbers, average length of articulation and length of pauses between the linguistic units, as well as between the samples, was shorter in males for each of these five minutes and for the „average“ minute. The maximum intensity of speech was higher in males for each of the five minutes. Average duration of mispronunciations, with end results being correct, was longer in women in the first, second, and fourth minute, as well as for the „average“ minute. A conclusion may be drawn that shorter utterances and pauses in men suggest the advantage on the part of men in SSS task, and not greater verbal fluency in general in men.
Nasal Carriage of Staphylococcus aureus in Healthy Adults and in School Children
Authors: Dinić Marina , Vuković Slavica , Stanković Đorđević Dobrila , Bogdanović Milena 
Published: February 2013

Summary
Staphylococcus aureus (S. aureus) is a microorganism that colonizes the skin and mucosal surfaces of healthy individuals, but it is also one of the most common causes of community-acquired and hospital infections. Nasal carriage of S. aureus represents a major risk factor for the development of infection with this bacterium. A special therapeutic problem are methicillin-resistant isolates of S. aureus (MRSA). The aim of this study was to assess the nasal carriage of S. aureus in healthy individuals in the local community, and the sensitivity of the microorganism to antibiotics. The study enrolled 56.868 healthy individuals aged 19 to 65 years, and 2.040 healthy school children aged 15 to 19 years. Specimens to be studied were obtained from anterior nares. We used the disk diffusion method (Kirby-Bauer) on Mueller- Hinton agar to assess the sensitivity of isolated S. aureus. S. aureus was isolated in 1.381 (2.34%) respondents. Positive findings were obtained in 2.33% of adult examinees, and in 2.59% of studied school children. We found a low level of susceptibility only to penicillin (5.36%). The susceptibility of S. aureus isolates to all other tested antibiotics was present in a high percentage, with the lowest percentage of susceptibility to doxycycline (71.54%) and erythromycin (86.09%). The highest percentage of susceptibility of tested isolates was reported for fusidic acid (99.27%). In relation to the total number of S. aureus isolates from nasal swabs in adults, MRSA was present in 8.96% (119 isolates), while there were 4 MRSA isolates from nasal swabs in school children. In this study, we established a low percentage of nasal carriage of S. aureus in the population of healthy individuals, but a high percentage of MRSA.
External Fixation in the Management of Closed Segmental Tibial Fractures
Authors: Golubović Zoran , Stojiljković Predrag , Golubović Ivan , Radovanović Zoran , Višnjić Aleksandar , Ristić Branko , Kutlešić Stojanović Katarina , Trenkić Milan , Najman Stevo , Trajanović Miroslav 
Published: February 2013

Summary
Segmental fractures represent the interruption of bone integrity at two or more levels. In these fractures, a wide zone of injury (damage of all structures of the lower leg) creates very unsuitable biological conditions for healing of the fracture. Because of the damage of both intramedullary and periostal vascularization, segmental fractures are predisposed to slow healing and development of pseudoarthrosis.
The aim of the paper was to present the results of treatment of patients with closed segmental tibial fractures treated by external fixation.
Within the period between January 1, 1998 and June 31, 2012 in the Clinical Center Niš, 26 patients with closed segmental fractures of the tibia were treated. The assessment of outcomes of treatment of closed segmental tibial fractures by external fixation was performed on a series of 24 patients. The mean age was 43.57 years. All the patients were treated by Mitković unilateral external fixator produced by “Trafix” firm.
Fracture healing occurred in 20 (83.33%) patients; four (16.67%) patients reported significant complications in the course of treatment that required further surgical treatment.
By applying the method of external fixation in the treatment of closed segmental tibial fractures, reposition of fragments is achieved through a small incision, with pins of exteranal fixator placed outside the fracture zone to prevent further damage of intramedullary and periosteal bone vascularisation, which is very important for fracture healing.
Functional warp-knitted fabrics with integrated superelastic niti filaments
Authors: Janouchova Katerina , Heller Ludek , Vysanska Monika 
Published: February 2013

Abstract

We report on a particular direction of currently conducted extended research on novel textiles with integrated thin
metallic filaments made of an intermetallic shape memory NiTi alloy exhibiting functional behaviour such as
superelastic deformation up to 10% and a thermally induced shape memory effect. Within this research direction
we focus on development of single and multi-layered warp-knitted fabrics that are directionally reinforced with
superelastic NiTi filaments. First, we describe the expected properties of such novel structures and their potential
applications. Second, we present the functional thermomechanical behaviour of applied superelastic NiTi
filaments. Third, we address questions related to the design and fabrication of warp-knitted fabrics with integrated
NiTi filaments. Then, we describe experimental methods applied on novel functional textiles in order to evaluate
their functional properties. Finally, we present and discuss results of experiments carried out on these novel
functional textiles.
Generation of micro-sized conductive lines on glass fibre fabrics by inkjet printing
Authors: Irurzuna Unai Balda , Dutschka Victoria , Calvimontesb Alfredo , Akkermana Remko 
Published: February 2013

Abstract

Micro-sized lines were inkjet printed on glass fibre fabrics using different droplet spacing. A conductive ink
containing silver nanoparticles was used in this study. Glass fibre fabrics were differently pre-treated to avoid
spontaneous spreading of the ink dispersion. The sample topography was examined using scanning electron,
optical and confocal microscopy with a chromatic sensor. Printability conditions were discussed based on the
results of topographic characterization and wettability measurements.
Intrapartum Vibroacoustic Stimulation Test and Cardiotocography for the Prediction of Neonatal Outcome
Authors: Bano Imam , Noor Nasreen , Kavitha C 
Published: February 2013

ABSTRACT

Objectives
To evaluate the role of intrapartum vibroacoustic stimulation (VAST) and cardiotocography (CTG) for the prediction of neonatal outcome.

Materials and methods
One hundred and twenty-five patients in labor with cephalic presentation were selected and subjected to CTG and VAST was done further to find out whether fetus is reactive or nonreactive and findings were correlated with the fetal outcome.

Results
VAST is a good predictor of fetal well being. It is less time consuming, inexpensive and technically easy to perform. In developing countries, where fetal scalp blood sampling is not available in all institutions, VAST can effectively be used as a clinical tool to compliment abnormal CTG traces for better prediction of fetal outcome.

How to cite this article
Kavitha C, Bano I, Noor N. Intrapartum Vibroacoustic Stimulation Test and Cardiotocography for the Prediction of Neonatal Outcome. J South Asian Feder Obst Gynae 2012;4(3):141-143.
Mass Per Abdomen: A Diagnostic Dilemma
Authors: Sundari N , Swarup Asha , Prabhu Vinay MD 
Published: February 2013

ABSTRACT
A P2L2 postmenopausal lady came with a history of mass PV with difficulty to walk and pain in the left hip. She also had a scan report showing a left complex adnexal mass suggesting ovarian malignancy. GPE showed a vague mass in the LIF which on CT scan was diagnosed as a retroperitoneal neoplasm measuring 100 × 70 × 80 mm. Core needle biopsy of the mass came as poorly differentiated metastatic carcinoma. No primary found. Palliative chemotherapy for 6 cycles with Paclitaxel and Cisplatin was given and the mass completely regressed in size.

How to cite this article
Jyothi GS, Sundari N, Prabhu VMD, Swarup A. Mass Per Abdomen: A Diagnostic Dilemma. J South Asian Feder Obst Gynae 2012;4(3):161-163.
Redox‐active LBL films via in situ template polymerization of hydroquinone
Authors: He Jian , Guan Ying , Zhang Yongjun 
Published: February 2013

AbstractNew redox‐active hydrogel thin films with poly(hydroquinone) (PHQ) as polymeric redox couple and chitosan hydrogel as matrix are synthesized. Single‐component layer‐by‐layer films of chitosan are first fabricated in a uniform and reproducible manner, which is proved by UV and AFM studies. The chitosan films are then treated in acidic hydroquinone (HQ) solution to introduce PHQ. In situ generation of PHQ in the films is proved by UV and FTIR spectroscopy. PHQ formation also results in an increased film roughness and thickness. We confirmed that oxygen acts as oxidant and chitosan acts as template in the polymerization of HQ. Cyclic voltammogram of the film presents two oxidation peaks at 0.21 and 0.75 V and one reduction peak at −0.15 V(vs Ag/AgCl), indicating the film, which is originally not redox‐active, becomes redox‐active after the introduction of PHQ. The new redox‐active films may find applications in amperometric biosensors. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013
Novel family members of CYP109 from Sorangium cellulosum So ce56 exhibit characteristic biochemical and biophysical properties
Authors: Khatri Yogan , Hannemann Frank , Girhard Marco , Kappl Reinhard , Même Aurélie , Ringle Michael , Janocha Simon , Leize‐Wagner Emmanuelle , Urlacher Vlada B. , Bernhardt Rita 
Published: February 2013

AbstractThe members of the CYP109 family (CYP109C1, CYP109C2, and CYP109D1) from Sorangium cellulosum So ce56 are among the 21 P450 enzymes, of which only CYP109D1 and CYP264B1 have so far been functionally characterized. Here, we attempted to characterize two other P450s (CYP109C1 and CYP109C2) for the first time and compare their biochemical, biophysical, and functional properties to those of the fatty acid hydroxylating CYP109D1. Considering the physiological importance of fatty acids, we investigated saturated fatty acid binding and conversion for all members of the CYP109 family. The interaction between the CYP109 members and different autologous/heterologous redox partners was compared using Biacore measurements in which only CYP109D1 and bovine adrenodoxin (Adx) formed a complex. Surprisingly, this interaction was similarly efficient as the interaction of Adx with its mammalian redox partners. The in vitro reconstitution assays showed no activity when using CYP109C1, although substrate binding was demonstrated; also, there was subterminal hydroxylation of saturated fatty acids, when using CYP109C2 and CYP109D1, where CYP109D1 was a much more efficient fatty acid hydroxylase. Interestingly, the hydroxylation position moved inside the fatty acid chain when using long‐chain fatty acids, thus producing possible precursors for physiologically important products.