bluuebunny/crossref_metadata_2025_split huggingface dataset:
Benefits of robotic gait assistance with ATLAS 2030 in children with cerebral palsy
Authors: Castro Pilar , Martí María , Oliván-Blázquez Bárbara , Boñar Nuria , García Violeta , Gascón-Santos Santiago , Panzano Alicia , Vela Sara , Tajadura Sara , Peña Ana , Tris-Ara María Josefa 
Published: July 2024

ObjectiveThis study aims to assess the impact of integrating ATLAS 2030 into the conventional therapy regimen for children with Cerebral Palsy (CP) compared to conventional therapy alone regarding gross motor function, range of motion (ROM) and spasticity.DesignA non-randomized controlled trial conducted in outpatient rehabilitation settings and special education schools, following the recommendations by the Consolidated Standards of Reporting Trials (CONSORT) statement.ParticipantsThirty children with CP divided into intervention and control groups.InterventionThe intervention group received three months of therapy (twice per week) with the ATLAS 2030 device in addition to their standard therapy, while the control group underwent standard therapy alone.Main outcome measureGross motor function assessed using the Gross Motor Function Measure of 88 items (GMFM-88).Secondary outcomesSpasticity, measured by the Modified Ashworth Scale (MAS), and ROM of the lower limbs.ResultsStatistically significant differences were observed between groups, in favour the intervention group, in both the GMFM-88 total score and dimension A, B and D. Similar findings were noted for spasticity and ROM, demonstrating significant improvements in the intervention group.ConclusionATLAS 2030 proves to be a safe and valuable tool for the rehabilitation of children with CP, showing improvements in motor function, spasticity and ROM.
Machine learning-based prediction model for the efficacy and safety of statins
Authors: Xiong Yu , Liu Xiaoyang , Wang Qing , Zhao Li , Kong Xudong , Da Chunhe , Meng Zuohuan , Qu Leilei , Xia Qinfang , Liu Lihong , Li Pengmei 
Published: July 2024

ObjectiveThe appropriate use of statins plays a vital role in reducing the risk of atherosclerotic cardiovascular disease (ASCVD). However, due to changes in diet and lifestyle, there has been a significant increase in the number of individuals with high cholesterol levels. Therefore, it is crucial to ensure the rational use of statins. Adverse reactions associated with statins, including liver enzyme abnormalities and statin-associated muscle symptoms (SAMS), have impacted their widespread utilization. In this study, we aimed to develop a predictive model for statin efficacy and safety based on real-world clinical data using machine learning techniques.MethodsWe employed various data preprocessing techniques, such as improved random forest imputation and Borderline SMOTE oversampling, to handle the dataset. Boruta method was utilized for feature selection, and the dataset was divided into training and testing sets in a 7:3 ratio. Five algorithms, including logistic regression, naive Bayes, decision tree, random forest, and gradient boosting decision tree, were used to construct the predictive models. Ten-fold cross-validation and bootstrapping sampling were performed for internal and external validation. Additionally, SHAP (SHapley Additive exPlanations) was employed for feature interpretability. Ultimately, an accessible web-based platform for predicting statin efficacy and safety was established based on the optimal predictive model.ResultsThe random forest algorithm exhibited the best performance among the five algorithms. The predictive models for LDL-C target attainment (AUC = 0.883, Accuracy = 0.868, Precision = 0.858, Recall = 0.863, F1 = 0.860, AUPRC = 0.906, MCC = 0.761), liver enzyme abnormalities (AUC = 0.964, Accuracy = 0.964, Precision = 0.967, Recall = 0.963, F1 = 0.965, AUPRC = 0.978, MCC = 0.938), and muscle pain/Creatine kinase (CK) abnormalities (AUC = 0.981, Accuracy = 0.980, Precision = 0.987, Recall = 0.975, F1 = 0.981, AUPRC = 0.987, MCC = 0.965) demonstrated favorable performance. The most important features of LDL-C target attainment prediction model was cerebral infarction, TG, PLT and HDL. The most important features of liver enzyme abnormalities model was CRP, CK and number of oral medications. Similarly, AST, ALT, PLT and number of oral medications were found to be important features for muscle pain/CK abnormalities. Based on the best-performing predictive model, a user-friendly web application was designed and implemented.ConclusionThis study presented a machine learning-based predictive model for statin efficacy and safety. The platform developed can assist in guiding statin therapy decisions and optimizing treatment strategies. Further research and application of the model are warranted to improve the utilization of statin therapy.
A systematic review and meta-analysis comparing the impact of tenofovir and entecavir on the prognosis of hepatitis B virus-related hepatocellular carcinoma patients undergoing liver resection
Authors: Hu Lingbo , Yang Chao , Qiao Yingli , Wang Aidong 
Published: July 2024

BackgroundTenofovir (TDF) and entecavir (ETV) are highly effective and well-tolerated nucleos(t)ide analogs commonly prescribed for hepatitis B virus (HBV) treatment. Yet, it is unclear whether survival outcomes differ for HBV-related hepatocellular carcinoma (HCC) patients treated with ETV and TDF. Thus, this meta-analysis aimed to compare the prognostic effectiveness of ETV and TDF in HBV-related HCC patients.MethodsWe comprehensively searched four databases, PubMed, Web of Science, Embase, and the Cochrane Library, to identify pertinent studies utilizing keywords “entecavir,” “tenofovir,” “hepatocellular carcinoma,” and “liver resection.” Our primary outcomes of interest encompassed overall survival (OS), recurrence-free survival (RFS), early recurrence, and late recurrence. The statistical effect size for these measures was expressed in terms of hazard ratios (HRs).ResultsOur search yielded 10 studies encompassing 11 datasets involving 7,400 patients. Our meta-analysis revealed that patients treated with TDF achieved better OS (HR = 0.53; 95% confidence interval [CI] = 0.40–0.70, p &lt; 0.0001), RFS (HR = 0.68; 95% CI = 0.57–0.80; p &lt; 0.0001), early recurrence (HR = 0.80; 95% CI = 0.67–0.94; p &lt; 0.0077), and late recurrence (HR = 0.64; 95% CI = 0.43–0.97; p = 0.0368). We detected publication bias potentially affecting OS but not RFS.ConclusionOur findings demonstrated that TDF outperformed ETV regarding RFS for HBV-related HCC patients. However, to bolster the evidence and establish more conclusive conclusions, further validation via extensive and high-quality randomized controlled trials is essential.Systematic Review Registrationhttps://www.crd.york.ac.uk/prospero/#recordDetails, identifier CRD 42024542579.
Effectiveness of engaging religious leaders in maternal health education for improving maternal health service utilization in Ethiopia: cluster randomized controlled trial
Authors: Sadore Abinet Arega , Kebede Yohannes , Birhanu Zewdie 
Published: July 2024

IntroductionHigh mortality rates for pregnant women and their new-borns are one of Africa’s most intractable public health issues today, and Ethiopia is one of the countries most afflicted. Behavioral interventions are needed to increase maternal health service utilizations to improve outcomes. Hence, this trial aimed to evaluate effectiveness of trained religious leaders’ engagement in maternal health education on maternal health service utilization.MethodsThe study employed a cluster-randomized controlled community trial that included baseline and end-line measurements. Data on end points were gathered from 593 pregnant mothers, comprising 292 and 301 individuals in the intervention and control groups, respectively. In the intervention group, the trained religious leaders delivered the behavioral change education on maternal health based on intervention protocol. Unlike the other group, the control group only received regular maternal health information and no additional training from religious leaders. Binary generalized estimating equation regression analysis adjusted for baseline factors were used to test effects of the intervention on maternal health service utilization.ResultsFollowing the trial’s implementation, the proportion of optimal antenatal care in the intervention arm increased by 21.4% from the baseline (50.90 vs. 72.3, p ≤ 0.001) and the proportion of institutional delivery in the intervention group increased by 20% from the baseline (46.1% vs. 66.1%, p ≤ 0.001). Pregnant mothers in the intervention group significantly showed an increase of proportion of PNC by 22.3% from baseline (26% vs. 48.3%, p ≤ 0.001). A statistically significant difference was observed between in ANC4 (AOR = 2.09, 95% CI: 1.69, 2.57), institutional delivery (AOR = 2.36, 95% CI: 1.94, 2.87) and postnatal care service utilization (AOR = 2.26, 95% CI: 1.79, 2.85) between the intervention and control groups.ConclusionThis research indicated that involving religious leaders who have received training in maternal health education led to positive outcomes in enhancing the utilization of maternal health services. Leveraging the influential position of these religious leaders could be an effective strategy for improving maternal health service utilization. Consequently, promoting maternal health education through religious leaders is advisable to enhance maternal health service utilization.Clinical trial registration: [https://clinicaltrials.gov/], identifier [NCT05716178].
THE IMPACT OF THE BOYCOTT PHENOMENON ON SWITCHING INTENTIONS FROM FOREIGN FASTFOOD CHAINS TO LOCAL OUTLETS
Authors: Salma Adilah , Rabbaniah Nadiah , Nuh Ahmad , Wibowo Finantyo Eddy 
Published: July 2024

This journal aims to analyze the impact of the boycott phenomenon on the intention to switch from foreign fried chicken restaurants such as McDonald's or KFC to local fried chicken restaurants such as D'kriuk or Sabana. Basically, the boycott phenomenon has become a major highlight in boycotting pro-Israel products. This is known from several examples of food products that allegedly provide free food for Zionist soldiers, namely McDonald's and KFC. In addition, the boycott that occurred against this brand was due to its connection with Israel, where there has been a conflict between Palestine and Israel. By boycotting McDonald's or KFC brands that have supported Israeli crimes, we can help stop Israeli aggression against Palestine and fight for the independence and freedom of the Palestinian people who have been colonized by Israel. Through a literature review and data analysis, this article explores the factors that influence consumers' intentions to switch from foreign to local brands in the context of the boycott phenomenon. When viewed through the consumer literature, there is a significant influence on the intention to switch from foreign brands such as McDonald's or KFC to local brands such as D'kriuk or Sabana. The results of this study are expected to provide valuable insights for fast food industry stakeholders in dealing with the challenges faced by the boycott phenomenon and strategies to maintain consumer loyalty. Keywords: Switching Intention, Boycott Intention, Alternative Attractiveness
THE EFFECT OF CUSTOMER SATISFACTION AND BRAND PREFERENCE ON REPURCHASE INTENTION OF MIXUE PRODUCTS DUE TO THE PRESENCE OF AICHA PRODUCTS
Authors: Khalidah Zhafirah Al , Fakhriyatuzzahrah Fakhriyatuzzahrah 
Published: July 2024

Penelitian ini berfokus pada bagaimana preferensi merek dan kepuasan pelanggan mempengaruhi niat konsumen untuk membeli kembali produk Mixue sebagai tanggapan terhadap ketersediaan produk Aicha. Penelitian ini menggunakan data kuantitatif, dengan 239 jumlah responden. Penelitian ini menunjukkan bahwa preferensi merek dan kepuasan pelanggan memiliki dampak yang menguntungkan dan substansial pada niat konsumen untuk membeli kembali produk Mixue. Hal ini menunjukkan bahwa konsumen yang lebih senang dengan produk Mixue lebih cenderung untuk memotivasi merek dan lebih mungkin untuk membeli produk mixue di masa depan. Studi ini menyimpulkan bahwa tidak ada hubungan antara ketersediaan barang Aicha dan kebahagiaan konsumen, preferensi merek, atau keinginan untuk membeli kembali Mixue. Hasil penelitian ini berkontribusi pada pemahaman tentang bagaimana kepuasan pelanggan dan preferensi untuk merek mempengaruhi niat membeli Mixue, serta bagaimana kehadiran produk Aicha tidak mempengaruhi perilaku pelanggan terhadap produk Mixue.
Kata kunci: Customer satisfaction, brand preference, repurchase intention
Concept of Strategic Management of Industrial Enterprise
Authors: Бирюкова В.В. 
Published: July 2024

В статье обосновывается положение о том, что доминирующие сегодня в менеджменте и стратегическом управлении концепции и теоретические модели основываются на тех или иных направлениях мейнстрима экономической теории, опирающихся на принцип методологического индивидуализма. Общую концепцию стратегического управления предлагается разрабатывать исходя из того, что в системе факторов стратегических перемен экономико-культурные ценности занимают центральное место, все другие переменные выражают результат конструирования организационно-технологических и финансово-экономических изменений на основе принятия, воплощения и поддержки соответствующих экономических ценностей.
The article substantiates the position that the dominant today in management and strategic management concepts and theoretical models are based on certain directions of the mainstream of economic theory, based on the principle of methodological individualism. It is proposed to develop the general concept of strategic management based on the fact that in the system of factors of strategic change economic and cultural values occupy a central place, all other variables express the result of designing organizational-technological and financial-economic changes based on the adoption, implementation and support of corresponding economic values.
Relationships Marketing as a Basis for Consumers’ Engagement in Touristic Product
Authors: Сажина А.И. 
Published: July 2024

В статье рассматриваются теоретические аспекты маркетинга взаимоотношений на примере анализа сайта туристической фирмы, реализующей некоторые принципы данного вида маркетинга. Актуальность данной работы обусловлена необходимостью внедрения новых моделей взаимодействия с пользователем, повышающих его вовлеченность. В результате эмпирического исследования было выявлено, что потребители, находящиеся на сайте и видящие страницы сайта с элементами маркетинга взаимоотношений, чаще оставляли заявки для совершения покупки туристского продукта.
The article investigates the theoretical aspects of relationships marketing using the example of a travel company website that implements some of the principles of this type of marketing. The relevance of this work is due to the need to introduce new models of interaction with the user, increasing the involvement and ensuring the development of the product in communication with the target audience. As a result of the study, it was revealed that consumers who, while on the site, saw pages of the site with elements of relationships marketing, more often left bids for making a purchase of a tourist product.
On the Issue of Economic and Legal Understanding of Cryptocurrency Relations
Authors: Абакаров Ю.А. , Кузяшев А.Н. , Нуркаева М.К. , Шаяхметов И.Ф. 
Published: July 2024

В статье исследованы вопросы, связанные с экономико-правовыми аспектами развития криптовалютных отношений и блокчейн-технологий. Авторы статьи считают, что криптовалюта является лишь модификацией токенов по принципу децентрализации создания и переходных операций.
The article examines issues related to the economic and legal aspects of the development of cryptocurrency relations and blockchain technologies. The authors of the article believe that cryptocurrency is only a modification of tokens on the principle of decentralization of creation and transitional operations.
Retrospective Analysis of Higher Education in Europe
Authors: Атаханов Р.А. 
Published: July 2024

В статье представлен краткий ретроспективный анализ процесса реформирования высшего образования в Европе, в частности Болонская декларация и Лиссабонская стратегия Европейского Союза, определившие принципы реформирования докторантуры, институциональные условия обучения, статус докторанта, надзора и финансирования данного процесса. Рассматривается концепция организационного поля и инструментов управления процессами реформирования докторантуры в Европе.
The article presents a brief retrospective analysis of the process of reforming higher education in Europe, in particular the Bologna declaration and the Lisbon strategy of the European Union, which determined the principles of reforming doctoral studies, institutional learning conditions, doctoral status, supervision and financing of this process. The concept of the organizational field and management tools for the process of reforming doctoral studies in Europe is considered.
Modern Model of Russian Federalism: the Risks of «Verticalization»
Authors: Дорожкин Ю.Н. 
Published: July 2024

В статье рассматриваются проблемы российского федерализма в контексте мировых тенденций децентрализации, регионализации и демократизации власти. Отмечается тренд в России к вертикализации федерализма, что создает новые риски и угрозы. Предлагаются шаги к демократизации федеративного устройства в современной России. Подчеркиваются безальтернативность реального федерализма в России и наличие для этого необходимых институций и ресурсов.
The report examines the problems of Russian federalism in the context of global trends of decentralization, regionalization and democratization. There is a trend in Russia towards the verticalization of federalism, which creates new risks and threats. The author proposed a number of steps to the democratization of the federal structure in modern Russia. It is emphasized that there is no alternative to real federalism in Russia and the availability of the necessary institutions and resources for this.
Information Threats of Modern Times and Public Administration Bodies
Authors: Бунтовский С.Ю. , Тонян М.Н. 
Published: July 2024

В статье рассматривается проблема влияния информационных технологий на жизнь общества, возросшего до так называемой информационной войны, глобально охватывающей все страты общества и различные государства. Развитие информационных технологий открыло неограниченные возможности для манипулирования общественным мнением и скрытого вмешательства во внутренние дела любого государства.
The article deals with the problem of the influence of information technologies on the life of society, which has increased to the so-called information war, globally covering all strata of society and various states. The development of information technologies has opened up unlimited opportunities for manipulating public opinion and covert interference in the internal affairs of any state.
Effect of Percutaneous Coronary Intervention on Central Hemodynamic Parameters in Elderly Patients
Authors: Агабабян И.Р. , Ярашева З.Х. 
Published: July 2024

Цель. Оценка годовой динамики лабораторных и эхокардиографических характеристик пациентов пожилого возраста после проведения стентирования коронарных артерий и выявление ранней ХСН. Материалы и методы. В исследовании приняли участие 80 пациентов с симптомами хронической сердечной недостаточности после проведения стентирования коронарных артерий. Объем исследования перед проведением стентирования коронарных артерий: подсчет баллов по шкале оценки клинического состояния (ШОКС), тест 6-минутной ходьбы (ТШХ), определение N-концевого предшественника натрийуретического пептида (NT-proBNP) в крови, эхокардиография. Средний возраст 76,17±3,29 года. Результаты. Количество баллов по шкале ШОКС за 12 месяцев снизилось с 3 (2; 4) до 1 (0; 1) балла (р<0,001) преимущественно из-за одышки. Прирост дистанции в ТШХ составил 85 (58; 116) м (р<0,001). Среднее значение NT-proBNP в группе снизилось с 470 (395;553) пг/мл до 364 (293; 443) пг/мл (р<0, 001). Заключение. Плановое ЧКВ со стентированием коронарных артерий у пациентов пожилого возраста должно тщательно обсуждаться, особенно когда имеется коморбидная патология. Необходимо проводить исследования, направленные на длительное наблюдение пациентов после ЧКВ, а также для подтверждения или исключения ХСН у всех пациентов изучить уровень NT-proBNP.
Purpose. To assess the annual dynamics of laboratory and echocardiographic characteristics of elderly patients after stenting of the coronary arteries and to identify early CHF. Materials and methods. The study involved 80 patients with symptoms of chronic heart failure after coronary artery stenting. The scope of the study before stenting the coronary arteries: scoring on a clinical status scale (CSS), 6-minute walk test (TST), determination of N-terminal precursor natriuretic peptide (NT-proBNP) in the blood, echocardiography. Average age 76.17±3.29 years. Results. The number of points on the SCS scale over 12 months decreased from 3 (2; 4) to 1 (0; 1) points (p<0.001), mainly due to shortness of breath. The increase in distance in TSH was 85 (58; 116) meters (p<0.001). The mean NT-proBNP value in the group decreased from 470 (395; 553) pg/ml to 364 (293; 443) pg/ml (p<0.001). Conclusion. Elective PCI with coronary artery stenting in elderly patients should be carefully discussed, especially when there is comorbid pathology. It is necessary to conduct studies aimed at long-term observation of patients after PCI, as well as to study the level of NT-proBNP in all patients to confirm or exclude CHF.
High-power and efficiency W-band InAlGaN/AlN/GaN high-electron-mobility transistors for future high-capacity wireless communications
Authors: Kumazaki Yusuke , Ozaki Shiro , Nakasha Yasuhiro , Okamoto Naoya , Yamada Atsushi , Ohki Toshihiro 
Published: July 2024

Abstract
This study describes high-power and high-efficiency W-band InAlGaN/AlN/GaN high-electron-mobility transistors (HEMTs) for future sub-terahertz wireless communications. A low-thermal-budget selective-area growth (SAG) process was developed to obtain low contact resistance with low trap states. Transmission lines and substrate structures were optimized to obtain high-thermal conductivity and low substrate resonance. Consequently, a high output power of 28.7 dBm (742 mW), output power density of 4.6 W mm−1, and power-added efficiency (PAE) of 28.0% were achieved with pre-matched InAlGaN/AlN/GaN HEMTs at 90 GHz, which were superior combination of output power and PAE compared to the conventional high-temperature SAG process.
RANCANG BANGUN MONITORING DEBIT AIR PDAM RUMAH TANGGA BERBASIS INTERNET OF THINGS (IOT)
Authors: Roza Yuni , KH Musliadi , Pernando Yonky , Syafrinal Ilwan , Kaharuddin Kaharuddin 
Published: July 2024

Indonesia adalah negara kepulauan yang memiliki iklim tropis. Negara ini juga terkenal dengan kekayaannya akan berbagai sumber daya alam salah satunya adalah air. Air merupakan sumber kebutuhan manusia yang penting untuk kelangsungan hidup yang digunakan untuk keperluan sehari-hari seperti untuk kosumsi, mandi, mencuci dan lainnya. Sebagai masyarakat tentunya harus memperhatikan kualitas dalam penggunaan air tersebut, dengan hal itu pemerintah menyediakan PDAM (Perusahaan Daerah Air Minum). Dalam penggunaaan fasilitas PDAM khususnya daerah Sulawesi Selatan Kabupaten Mamuju dibutuhkan monitoring besaran pemakaian setiap bulannya. Tampilan meteran yang masih berupa analog dan belum tercantumnya jumlah tarif atau tagihan yang harus dibayar oleh masyarakat. Jumlah tagihan yang harus dibayar merupakan hasil pencatatan oleh petugas PDAM yang datang tiap bulannya. Dengan hal tesebut dibutuhkan alat untuk memonitoring pemakaian dan jumlah tagihan yang akan dibayar oleh masyarakat berbasis Internet of Things (IoT). Dengan adanya alat pengontrolan yang berbasis IoT ini, masyarakat bisa melihat jumlah pemakaian air dan jumlah tarif yang harus dibayar tiap bulannya.