bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multi‐faceted approaches toward unravelling complex ecological networks
Authors: Namba Toshiyuki 
Published: March 2015

AbstractThe main theme of this Special Feature is the complexity‐stability relationship and diversity of interaction types. Five articles by leading authors are submitted. Studies on the relationship between complexity and stability have a long history of 40 years. Effect of multiple interaction types on structure and dynamics of an ecological network is a recent important subject to be resolved. In this preface, I briefly review the history of research on complexity‐stability relationship till the idea of diversity of interaction types appears.
Acute rhabdomyolysis and inflammation
Authors: Hamel Yamina , Mamoune Asmaa , Mauvais François‐Xavier , Habarou Florence , Lallement Laetitia , Romero Norma Beatriz , Ottolenghi Chris , de Lonlay Pascale 
Published: March 2015

AbstractRhabdomyolysis results from the rapid breakdown of skeletal muscle fibers, which leads to leakage of potentially toxic cellular content into the systemic circulation. Acquired causes by direct injury to the sarcolemma are most frequent. The inherited causes are: i) metabolic with failure of energy production, including mitochondrial fatty acid ß‐oxidation defects,LPIN1mutations, inborn errors of glycogenolysis and glycolysis, more rarely mitochondrial respiratory chain deficiency, purine defects and peroxysomal α‐methyl‐acyl‐CoA‐racemase defect (AMACR), ii) structural causes with muscle dystrophies and myopathies, iii) calcium pump disorder withRYR1gene mutations, iv) inflammatory causes with myositis. Irrespective of the cause of rhabdomyolysis, the pathology follows a common pathway, either by the direct injury to sarcolemma by increased intracellular calcium concentration (acquired causes) or by the failure of energy production (inherited causes), which leads to fiber necrosis. Rhabdomyolysis are frequently precipitated by febrile illness or exercise. These conditions are associated with two events, elevated temperature and high circulating levels of pro‐inflammatory mediators such as cytokines and chemokines. To illustrate these points in the context of energy metabolism, protein thermolability and the potential benefits of arginine therapy, we focus on a rare cause of rhabdomyolysis, aldolase A deficiency. In addition, our studies on lipin‐1 (LPIN1) deficiency raise the possibility that several diseases involved in rhabdomyolysis implicate pro‐inflammatory cytokines and may even represent primarily pro‐inflammatory diseases. Thus, not only thermolability of mutant proteins critical for muscle function, but also pro‐inflammatory cytokines per se, may lead to metabolic decompensation and rhabdomyolysis.
Spectrum of combined respiratory chain defects
Authors: Mayr Johannes A. , Haack Tobias B. , Freisinger Peter , Karall Daniela , Makowski Christine , Koch Johannes , Feichtinger René G. , Zimmermann Franz A. , Rolinski Boris , Ahting Uwe , Meitinger Thomas , Prokisch Holger , Sperl Wolfgang 
Published: March 2015

AbstractInherited disorders of mitochondrial energy metabolism form a large and heterogeneous group of metabolic diseases. More than 250 gene defects have been reported to date and this number continues to grow. Mitochondrial diseases can be grouped into (1) disorders of oxidative phosphorylation (OXPHOS) subunits and their assembly factors, (2) defects of mitochondrial DNA, RNA and protein synthesis, (3) defects in the substrate‐generating upstream reactions of OXPHOS, (4) defects in relevant cofactors and (5) defects in mitochondrial homeostasis. Deficiency of more than one respiratory chain enzyme is a common finding. Combined defects are found in 49 % of the known disease‐causing genes of mitochondrial energy metabolism and in 57 % of patients with OXPHOS defects identified in our diagnostic centre. Combined defects of complexes I, III, IV and V are typically due to deficiency of mitochondrial DNA replication, RNA metabolism or translation. Defects in cofactors can result in combined defects of various combinations, and defects of mitochondrial homeostasis can result in a generalised decrease of all OXPHOS enzymes. Noteworthy, identification of combined defects can be complicated by different degrees of severity of each affected enzyme. Furthermore, even defects of single respiratory chain enzymes can result in combined defects due to aberrant formation of respiratory chain supercomplexes. Combined OXPHOS defects have a great variety of clinical manifestations in terms of onset, course severity and tissue involvement. They can present as classical encephalomyopathy but also with hepatopathy, nephropathy, haematologic findings and Perrault syndrome in a subset of disorders.
Biodiesel Production Using a Carbon Solid Acid Catalyst Derived from β‐Cyclodextrin
Authors: Fu Xiao‐bo , Chen Jie , Song Xue‐li , Zhang Yuan‐ming , Zhu Yi , Yang Jun , Zhang Cheng‐wu 
Published: March 2015

AbstractA novel carbon solid acid catalyst was prepared by incomplete hydrothermal carbonization of β‐cyclodextrin into small polycyclic aromatic carbon sheets, followed by the introduction of –SO3H groups via sulfonation with sulfuric acid. The physical and chemical properties of the catalyst were characterized in detail. The catalyst simultaneously catalyzed esterification and transesterification reactions to produce biodiesel from high free fatty acid (FFA) containing oils (55.2 %). For the as‐prepared catalyst, 90.82 % of the oleic acid was esterified after 8 h, while the total transesterification yield of high FFA containing oils reached 79.98 % after 12 h. By contrast, the obtained catalyst showed comparable activity to biomass (such as sugar, starch, etc.)‐based carbon solid acid catalyst while Amberlyst‐15 resulted in significantly lower levels of conversion, demonstrating its relatively high catalytic activity for simultaneous esterification and transesterification. Moreover, as the catalyst can be regenerated, it has the potential for use in biodiesel production from oils with a high FFA content.
Hip decompression of unstable slipped capital femoral epiphysis: A systematic review and meta-analysis
Authors: Ibrahim Talal , Mahmoud Shady , Riaz Muhammad , Hegazy Abdelsalam , Little David G. 
Published: March 2015

Purpose Slipped capital femoral epiphysis (SCFE) is one of the most common adolescent hip conditions. Unstable SCFE is characterized by sudden and severe hip pain with the inability to weight bear, even with crutches. Osteonecrosis of the femoral head is increased in patients with unstable SCFE. The aim of our study was to systematically review the literature that compares hip decompression to no hip decompression of unstable SCFE. Methods We searched several databases from 1946 to 2014 for any observational or experimental studies that evaluated hip decompression and osteonecrosis of unstable SCFE. We performed a meta-analysis using a random effects model to pool odds ratios (ORs) for the comparison of osteonecrosis between patients undergoing hip decompression and no hip decompression. We also investigated the type of hip decompression performed. Descriptive, quantitative, and qualitative data were extracted. Results Of the 17 articles identified, nine studies (eight case series and one retrospective cohort study) were eligible for the meta-analysis, with a total of 302 unstable SCFE. The pooled OR = 0.91 of osteonecrosis between hip decompression and no hip decompression was in favor of hip decompression, but was not statistically significant [95 % confidence interval (CI): 0.47, 1.75; p = 0.54, I2 = 0 %]. No significant differences in the rates of osteonecrosis were detected in unstable SCFE with open and percutaneous hip decompression alone (OR = 0.97, 95 % CI: 0.36, 2.62; p = 0.69, I2 = 19.1 %) or hip decompression with bony procedures (OR = 0.99, 95 % CI: 0.35, 2.79; p = 0.69, I2 = 0 %). Conclusions The cumulative evidence at present does not indicate an association between hip decompression and a lower rate of osteonecrosis of unstable SCFE. However, hip decompression of unstable SCFE remains an option that can potentially decompress the intracapsular hip pressure and optimize the blood flow to the femoral head. Thus, multicenter prospective cohort studies are required and will be able to answer this question with more certainty and a higher level of evidence. Level of evidence Level III/IV.
Emerging LNG-fueled ships in the Chinese shipping industry: a hybrid analysis on its prospects
Authors: Wan Chengpeng , Yan Xinping , Zhang Di , Shi Jing , Fu Shanshan , Ng Adolf K. Y. 
Published: March 2015

Abstract
With the prosperity of global shipping industry, a variety of shipping-induced environmental problems and increasingly rigid emission restrictions have drawn more attention to an emerging marine fuel—liquefied natural gas (LNG), a clean and efficient energy that conforms to the essence of green shipping. Although with superiority using onboard, there are only fewer than 40 fully LNG-fueled ships in service worldwide by June 2013, and the quantity of LNG-fueled ships in operation is even much lower in China. Moreover, the majority of those in China are inland ships, which mainly navigate along the Yangtze River and canals. By using the SWOT (strengths, weaknesses, opportunities, and threats) analysis in combination with the analytic hierarchy process (AHP), this paper analyzes the development prospect of LNG-fueled ships in inland waterway transportation in China, aiming to fill the gaps of inadequate understanding of the new marine energy. This paper offers some insight on the prospects of the application of LNG in the Chinese shipping industry and simultaneously provides useful information to stakeholders and policy makers for decision-making on the development of LNG-fueled ships.
Right coronary artery perforation by an active‐fixation atrial pacing lead resulting in life‐threatening tamponade
Authors: Nakagawa Eiichiro , Abe Yukio , Komatsu Ryushi , Naruko Takahiko , Itoh Akira 
Published: March 2015

AbstractCardiac tamponade resulting from perforation of a cardiac chamber is a relatively rare complication of pacemaker implantation. We report the first case of perforation of the right coronary artery related to the implantation of a screw‐in atrial pacing lead, presenting as life‐threatening cardiac tamponade.We report the case of a 72‐year‐old woman with complete atrioventricular block and dyspnea on exertion. A permanent pacemaker was implanted with bipolar Medtronic active‐fixation leads positioned in the right atrial appendage and at the right ventricular basal septum without any difficulty. Approximately 3.5 h after the procedure, the patient complained of nausea, and the systolic blood pressure decreased to less than 60 mmHg. Echocardiography revealed a large pericardial effusion. Because the effects of pericardiocentesis lasted for less than an hour, the patient underwent a thoracotomy. After evacuation of a massive hemopericardium, bright red blood was seen gushing out from the right coronary artery, which was located on the opposite site of the right atrial appendage where a small portion of the screw tip was observed to be penetrating the atrial wall. The right coronary artery perforation was repaired using autologous pericardium‐reinforced 7–0 prolene mattress sutures.Perforation of the right coronary artery is a potential complication and should be part of the differential diagnosis of cardiac tamponade after pacemaker implantation.
Witchcraft, Justice, and Human Rights in Africa: Cases from Malawi
Authors: Ashforth Adam 
Published: March 2015

Abstract:The human rights approach to witchcraft accusations denies their validity and forecloses the possibility of a trial, fair or otherwise. While there is much to be said for a bracing rationalism in all aspects of life, evidence from Africa over the past couple of centuries shows no sign that witchcraft narratives lose their plausibility as a result of people being told that witches do not exist.
Africa’s Intoxicating Beer Markets
Authors: Hesse Brian J. 
Published: March 2015

Abstract:African beer markets are increasingly being commercialized. Select brewers are going to extraordinary lengths to attract new customers on the continent. Economic and business “life cycle” models usually indicate that this can only go on for a finite period, that industries, companies, and products, just like organisms, must move through stages of emergence and maturity to inevitable decline. Such expectations may be too rigid in the African context. Such are the continent’s dynamic economic and social realities that commercial brewers, and especially a handful of multinational corporations, look capable of staving off decline—an intoxicating prospect for them indeed.
Grand Designs: Assessing the African Energy Security Implications of the Grand Inga Dam
Authors: Green Nathaniel , Sovacool Benjamin K. , Hancock Kathleen 
Published: March 2015

Abstract:In May 2013 the Democratic Republic of the Congo (DRC) announced that construction of the world’s largest hydroelectric project will begin in October 2015. Upon completion, according to the DRC, the project will bring electricity to half the African continent. With funding from South Africa, the World Bank, the African Development Bank, and others, the U.S.$80 billion Grand Inga Hydroelectric project will construct a 44,000 megawatt (MW) dam anchored to a new transmission network able to distribute electricity to all four of sub-Saharan Africa’s regional electricity power pools. While the dam promises to bring electricity to many millions of Africans who currently lack access, the project also poses risks to the citizens and environment of the DRC. To assess the complex tradeoffs, this article evaluates four dimensions that are part of an energy security framework: availability, affordability, efficiency, and stewardship. In doing so, it explores some of the governance challenges that arise in managing such a “mega-project.” The analysis also reveals tensions between national and regional energy security. It presents evidence that, under certain assumptions, the pursuit of enhanced security at the regional level may result in a net security loss for the DRC. Finally, the article provides suggestions for enhancing the decision-making process of those designing related national and regional energy strategies.
An Economic Analysis of Adherence Engineering to Improve Use of Best Practices During Central Line Maintenance Procedures
Authors: Nelson Richard E. , Angelovic Aaron W. , Nelson Scott D. , Gleed Jeremy R. , Drews Frank A. 
Published: March 2015

OBJECTIVEAdherence engineering applies human factors principles to examine non-adherence within a specific task and to guide the development of materials or equipment to increase protocol adherence and reduce human error. Central line maintenance (CLM) for intensive care unit (ICU) patients is a task through which error or non-adherence to protocols can cause central line-associated bloodstream infections (CLABSIs). We conducted an economic analysis of an adherence engineering CLM kit designed to improve the CLM task and reduce the risk of CLABSI.METHODSWe constructed a Markov model to compare the cost-effectiveness of the CLM kit, which contains each of the 27 items necessary for performing the CLM procedure, compared with the standard care procedure for CLM, in which each item for dressing maintenance is gathered separately. We estimated the model using the cost of CLABSI overall ($45,685) as well as the excess LOS (6.9 excess ICU days, 3.5 excess general ward days).RESULTSAssuming the CLM kit reduces the risk of CLABSI by 100% and 50%, this strategy was less costly (cost savings between $306 and $860) and more effective (between 0.05 and 0.13 more quality-adjusted life-years) compared with not using the pre-packaged kit. We identified threshold values for the effectiveness of the kit in reducing CLABSI for which the kit strategy was no longer less costly.CONCLUSIONAn adherence engineering–based intervention to streamline the CLM process can improve patient outcomes and lower costs. Patient safety can be improved by adopting new approaches that are based on human factors principles.Infect Control Hosp Epidemiol 2015;00(0): 1–7
Characteristics of Bacteremia in Pediatric Oncology Patients Based on Pathogen Classification as Associated with the Gastrointestinal Mucosa or Skin
Authors: Flagg Aron , Worley Sarah , Foster Charles B. 
Published: March 2015

Factors favoring blood stream infections associated with gastrointestinal mucosa versus skin organisms were explored. An observed difference was attributable to bacteremia from oral flora in patients with acute myelogenous leukemia or mucositis. Our data do not support the conclusion that isolation of enteric Gram-negatives is unrelated to the central catheter.Infect Control Hosp Epidemiol 2015;00(0): 1–4
Verified and validated calculation of unsteady dynamics of viscous hydrogen–air detonations
Authors: Romick C. M. , Aslam T. D. , Powers J. M. 
Published: March 2015

The dynamics of one-dimensional, piston-driven hydrogen–air detonations are predicted in the presence of physical mass, momentum and energy diffusion. The calculations are automatically verified by the use of an adaptive wavelet-based computational method which correlates a user-specified error tolerance to the error in the calculations. The predicted frequency of 0.97 MHz for an overdriven pulsating detonation agrees well with the 1.04 MHz frequency observed by Lehr in a shock-induced combustion experiment around a spherical projectile, thus giving a limited validation for the model. A study is performed in which the supporting piston velocity is varied, and the long time behaviour is examined for an initially stoichiometric mixture at 293.15 K and 1 atm. Several distinct propagation behaviours are predicted: a stable detonation, a high-frequency pulsating detonation, a pulsating detonation with two competing modes, a low-frequency pulsating detonation and a propagating detonation with many active frequencies. In the low-frequency pulsating mode, the long time behaviour undergoes a phenomenon similar to period-doubling. Harmonic analysis is used to examine how the frequency of the pulsations evolves as the supporting piston velocity is varied. It is found that the addition of viscosity shifts the neutral stability boundary by about 2 % with respect to the supporting piston velocity. As the supporting piston velocity is lowered, the intrinsic instability grows in strength, and the effect of viscosity is weakened such that the results are indistinguishable from the inviscid predictions.
Dietary magnesium deficiency affects gut microbiota and anxiety-like behaviour in C57BL/6N mice
Authors: Pyndt Jørgensen Bettina , Winther Gudrun , Kihl Pernille , Nielsen Dennis S. , Wegener Gregers , Hansen Axel K. , Sørensen Dorte B. 
Published: March 2015

ObjectiveMagnesium deficiency has been associated with anxiety in humans, and rodent studies have demonstrated the gut microbiota to impact behaviour.MethodsWe investigated the impact of 6 weeks of dietary magnesium deficiency on gut microbiota composition and anxiety-like behaviour and whether there was a link between the two. A total of 20 C57BL/6 mice, fed either a standard diet or a magnesium-deficient diet for 6 weeks, were tested using the light-dark box anxiety test. Gut microbiota composition was analysed by denaturation gradient gel electrophoresis.ResultsWe demonstrated that the gut microbiota composition correlated significantly with the behaviour of dietary unchallenged mice. A magnesium-deficient diet altered the gut microbiota, and was associated with altered anxiety-like behaviour, measured by decreased latency to enter the light box.ConclusionMagnesium deficiency altered behavior. The duration of magnesium deficiency is suggested to influence behaviour in the evaluated test.
High consumption of vegetable and fruit colour groups is inversely associated with the risk of colorectal cancer: a case–control study
Authors: Luo Wei-Ping , Fang Yu-Jing , Lu Min-Shan , Zhong Xiao , Chen Yu-Ming , Zhang Cai-Xia 
Published: March 2015

The colour of the edible portion of vegetables and fruit reflects the presence of specific micronutrients and phytochemicals. No existing studies have examined the relationship between the intake of vegetable and fruit colour groups and the risk of colorectal cancer. The present study, therefore, aimed to investigate these associations in a Chinese population. A case–control study was conducted between July 2010 and July 2014 in Guangzhou, China, in which 1057 consecutively recruited cases of colorectal cancer were frequency-matched to 1057 controls by age (5-year interval), sex and residence (rural/urban). A validated FFQ was used to collect dietary information during face-to-face interviews. Vegetables and fruit were classified into four groups according to the colour of their primarily edible parts: green; orange/yellow; red/purple; white. Unconditional logistic regression models were used to estimate the OR and 95 % CI. A higher consumption of orange/yellow, red/purple and white vegetables and fruit was inversely associated with the risk of colorectal cancer, with adjusted OR of 0·16 (95 % CI 0·12, 0·22) for orange/yellow, 0·23 (95 % CI 0·17, 0·31) for red/purple and 0·53 (95 % CI 0·40, 0·70) for white vegetables and fruit when the highest and lowest quartiles were compared. Total vegetable intake and total fruit intake have also been found to be inversely associated with colorectal cancer risk. However, the intake of green vegetable and fruit was not associated with colorectal cancer risk. The results of the present study, therefore, suggest that a greater intake of orange/yellow, red/purple and white vegetables and fruit is inversely associated with the risk of colorectal cancer.
Characterization of novel microsatellite markers forHyphantria cuneaand implications for other Lepidoptera
Authors: Cao L.J. , Wen J.B. , Wei S.J. , Liu J. , Yang F. , Chen M. 
Published: March 2015

AbstractThis is the first report of microsatellite markers (simple sequence repeats, SSR) for fall webworm,Hyphantria cunea(Drury) (Lepidoptera: Arctiidae), an important quarantine pest in some European and Asian countries. Here, we developed 48 microsatellite markers forH. cuneafrom SSR enrichment libraries. Sequences isolated from libraries were sorted into four categories and analyzed. Our results suggest that sequences classified asGroupedshould not be used for microsatellite primer design. The genetic diversity of microsatellite loci was assessed in 72 individuals from three populations. The number of alleles per locus ranged from 2 to 5 with an average of 3. The observed and expected heterozygosities of loci ranged from 0 to 0.958 and 0 to 0.773, respectively. A total of 18 out of 153 locus/population combinations deviated significantly from Hardy–Weinberg equilibrium. Moreover, significant linkage disequilibrium was detected in one pair of loci (1275 pairs in total). In the neutral test, two loci were grouped into the candidate category for positive selection and the remainder into the neutral category. In addition, a complex mutation pattern was observed for these loci, andFSTperformed better than didRSTfor the estimation of population differentiation in different mutation patterns. The results of the present study can be used for population genetic studies ofH. cunea.
THE BEST INTERESTS OF THE CHILD PRINCIPLE AS AN INDEPENDENT SOURCE OF INTERNATIONAL PROTECTION
Authors: Pobjoy Jason M 
Published: March 2015

AbstractThe Convention on the Rights of the Child, and the best interests principle codified in Article 3 in particular, is playing an increasingly significant role in decisions involving the admission or removal of a child from a host State. This article examines the extent to which the best interest principle may provide an independent source of international protection. That protection may, for instance, proscribe the removal of a child from a host State notwithstanding that the child is ineligible for protection as a refugee or protection under the more traditionalnon-refoulementobligations in international human rights law.