bluuebunny/crossref_metadata_2025_split huggingface dataset:
Treatment with Tumor Necrosis Factor Inhibitors in Axial Spondyloarthritis: Comparison Between Private Rheumatology Practices and Academic Centers in a Large Observational Cohort
Authors: Ciurea Adrian , Weber Ulrich , Stekhoven Daniel , Scherer Almut , Tamborrini Giorgio , Bernhard Jürg , Toniolo Martin , Villiger Peter M. , Zufferey Pascal , Kissling Rudolf O. , Michel Beat A. , Exer Pascale 
Published: November 2014

Objective.To evaluate the initiation of and response to tumor necrosis factor (TNF) inhibitors for axial spondyloarthritis (axSpA) in private rheumatology practices versus academic centers.Methods.We compared newly initiated TNF inhibition for axSpA in 363 patients enrolled in private practices with 100 patients recruited in 6 university hospitals within the Swiss Clinical Quality Management (SCQM) cohort.Results.All patients had been treated with ≥ 1 nonsteroidal antiinflammatory drug and > 70% of patients had a baseline Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) ≥ 4 before anti-TNF agent initiation. The proportion of patients with nonradiographic axSpA (nr-axSpA) treated with TNF inhibitors was higher in hospitals versus private practices (30.4% vs 18.7%, p = 0.02). The burden of disease as assessed by patient-reported outcomes at baseline was slightly higher in the hospital setting. Mean levels (± SD) of the Ankylosing Spondylitis Disease Activity Score were, however, virtually identical in private practices and academic centers (3.4 ± 1.0 vs 3.4 ± 0.9, p = 0.68). An Assessment of SpondyloArthritis international Society (ASAS40) response at 1 year was reached for ankylosing spondylitis in 51.7% in private practices and 52.9% in university hospitals (p = 1.0) and for nr-axSpA in 27.5% versus 25.0%, respectively (p = 1.0).Conclusion.With the exception of a lower proportion of patients with nr-axSpA newly treated with anti-TNF agents in private practices in comparison to academic centers, adherence to ASAS treatment recommendations for TNF inhibition was equally high, and similar response rates to TNF blockers were achieved in both clinical settings.
Projected Worldwide Disease Burden from Giant Cell Arteritis by 2050
Authors: De Smit Elisabeth , Palmer Andrew J. , Hewitt Alex W. 
Published: November 2014

Objective.To estimate and project the number of people affected worldwide by giant cell arteritis (GCA) by 2050. Modeling the number of people visually impaired as a result of this disease will help establish the projected morbidity and resource burden.Methods.A systematic literature review up to December 2013 was conducted using PubMed and ISI Web of Science. Studies reporting an incidence rate for GCA were used to model disease incident cases at regional and national levels. United Nations Population Prospect data were used for population projections. Morbidity burden was established through rates of visual impairment. The associated financial implications were calculated for the United States.Results.The number of incident cases of GCA will increase secondary to an aging population. By 2050, more than 3 million people will have been diagnosed with GCA in Europe, North America, and Oceania. About 500,000 people will be visually impaired. By 2050, in the United States alone, the estimated cost from visual impairment due to GCA will exceed US$76 billion. Inpatient care for patients with active GCA will total about US$1 billion. Management of steroid-related adverse events will increase costs further, with steroid-induced fractures estimated to total US$6 billion by 2050.Conclusion.Projecting disease burden for GCA on a global scale allows for optimization of healthcare planning and prioritization of research domains. Additional population-based studies are required to more accurately project worldwide disease burden. Our work highlights the future global disease burden of GCA, and illustrates the associated financial implications.
Neuroimaging and renal ultrasound manifestations of Oculocerebrorenal syndrome of Lowe
Authors: Allmendinger Andrew Mark , Desai Naman S. , Burke Alanna Teatom , Viswanadhan Narayan , Prabhu Sanjay P 
Published: November 2014

Oculocerebrorenal syndrome of Lowe (OCRL) is a multisystem disorder characterized by congenital cataracts, hypotonia, and cognitive developmental delay with renal complications developing in the first few months of life. Clinical and laboratory findings of Lowe syndrome are well documented. Though a small number of case reports describe the neuroimaging features and the renal ultrasound manifestations of this disease, a comprehensive review of all the imaging manifestations has not been reported. The authors present a case of OCRL and review the neuroimaging and renal ultrasound manifestations of this multisystem disease.
Les langues de spécialité sont-elles des argots comme les autres ?
Authors: Antoine Fabrice 
Published: November 2014

Les langues de spécialité sont-elles des argots comme les autres ? À moins que la question se pose dans l’autre sens ? L’auteur propose de croiser ici les points de vue du traducteur, du lexicographe, du lexicologue et de l’argotologue afin de tenter de déterminer la/les filiation(s) possible(s) entre argots et langues de spécialité, en quoi les uns ressemblent aux autres ou au contraire s’en distinguent, dans leurs caractéristiques, leurs moyens, leurs origines et modes de formation, leurs fonctions, hier et aujourd’hui, ou encore leur recours massif à la métaphore et leurs éventuelles résistances à traduction. L’auteur envisage d’aller fureter dans les contre-allées de la langue, afin d’y trouver, peut-être, de quoi nourrir une description concrète, illustrée, de deux cousines, dont l’une est respectable et l’autre pas.
L’anglais de spécialité en LEA à la croisée des domaines : étude de l’acquisition du lexique spécialisé
Authors: McAllister Julie , Belan Sophie 
Published: November 2014

Cet article propose d’étudier l’acquisition du lexique spécialisé dans le cadre d’un dispositif hybride d’enseignement-apprentissage de l’anglais des affaires dans la filière LEA. Après une brève exposition du contexte et de la méthodologie de la recherche, il présente les résultats d’une étude qualitative et quantitative menée à partir d’un corpus de productions écrites d’étudiants de Licence 1 LEA. L’objectif de l’étude était de montrer comment la fluidité, la précision et la complexité lexicale et syntaxique de la production écrite évoluent dans le cadre du dispositif hybride proposé. Les résultats obtenus montrent une évolution statistiquement significative de la fluidité, de la précision et de la complexité lexicale des productions, à des degrés divers en fonction du niveau des étudiants.
Researching legal terminology: a corpus-based proposal for the analysis of sub-technical legal terms
Authors: Marín María José , Rea Camino 
Published: November 2014

Cet article propose une nouvelle approche pour la description sémantique de « termes semi-techniques » à l’aide du modèle de « constellation lexicale » de Cantos et Sánchez (2001), qui permet la représentation visuelle de la trajectoire suivie par ce type de termes vers la spécialisation. Plusieurs auteurs mettent en avant le fait que l’utilisation de termes semi-techniques est une caractéristique saillante du lexique juridique. Cette étude met en évidence le fait que près de la moitié des termes dans un corpus juridique de 8,85 millions de mots recoupe des listes de vocabulaire d’anglais général comme la General Service List (GSL) de West (1953) ou les 3 000 mots d’anglais les plus courants du British National Corpus (BNC). Étant donné l’importance de ces termes dans cette variété d’anglais de spécialité et le manque d’étude dans la spécialité, les auteurs rendent compte de ce phénomène complexe en adoptant une perspective sémantique fondée sur un corpus. Cette étude a été réalisée au moyen d’une méthodologie qualitative et quantitative pour décrire le processus de spécialisation du terme légal semi-technique « charge », utilisé pour illustrer le modèle d’analyse.
Les « fleurs mathématiques » de la poésie et la fiction américaine contemporaine : enjeux d’une intersection littérature-mathématiques pour l’étude de l’anglais scientifique
Authors: Le Cor Gwen 
Published: November 2014

Cet article s’attache au dialogue que la littérature américaine contemporaine instaure avec les mathématiques et s’intéresse en retour aux enjeux de ce dialogue pour l’étude de l’anglais scientifique. Si l’on admet avec René Thom que le « formalisme mathématique » s’oppose en tout point au langage naturel, se pose alors le problème de la définition de ce que pourrait être l’objet « anglais des mathématiques ». La première partie de cette étude s’attache à cette question définitoire. L’article examine ensuite l’hypothèse que la littérature puisse proposer une expérience de pensée mathématique et donc être une voie d’accès privilégiée à l’anglais scientifique. En s’appuyant sur les réflexions de Brian Massumi, et de Jean-Luc Nancy l’article envisage enfin la manière dont la littérature permet de saisir le mode d’abstraction et l’affect des concepts mathématiques.
The future of ESP studies: building on success, exploring new paths, avoiding pitfalls
Authors: Williams Christopher 
Published: November 2014

L’auteur fournit dans cet article un résumé de l’état de l’art en anglais de spécialité (ASP) ; il souligne la façon dont l’ASP s’est développé et le rôle qu’il joue actuellement au sein de la recherche universitaire et de l’enseignement d’une langue étrangère. Il propose ensuite des voies sur lesquelles l’ASP peut évoluer dans le futur et il se penche en particulier sur les pistes suivantes : la nécessité d’une implication plus profonde dans des domaines non linguistiques (médecine, droit, ingénierie, économie, etc.) et de plus de dialogue avec les praticiens de ces domaines ; l’importance de l’étude des formes de vulgarisation du discours spécialisé et de leur enseignement ; l’exploration (et l’exploitation) du phénomène de la multimodalité en lien avec les études en ASP ; le potentiel de l’enseignement d’une matière par l’intégration d’une langue étrangère (EMILE/CLIL) ; la nécessité de veiller à ce que les études en ASP se penchent sur ce qui est à la fois innovant, pertinent et intéressant pour les enseignants et les praticiens. Cette brève présentation des études en ASP passées, présentes et futures est destinée en particulier aux chercheurs en ASP novices ou à ceux dont les connaissances en ASP sont réduites.
Nurses’ Perceptions of Family Presence during Resuscitation
Authors: Tudor Kelly , Berger Jill , Polivka Barbara J. , Chlebowy Rachael , Thomas Beena 
Published: November 2014

Background
Although strong evidence indicates that the presence of a patient’s family during resuscitation has a positive effect on the family, the practice is still controversial and is not consistently implemented.

Objectives
To explore nurses’ experience with resuscitation, perceptions of the benefits and risks of having a patient’s family members present, and self-confidence in having family presence at their workplace. Differences in demographic characteristics and relationships between nurses’ perceptions of self-confidence and perceived risks and benefits of family presence were evaluated.

Methods
The study was descriptive, with a cross-sectional survey design. A convenience sample of 154 nurses working in inpatient and outpatient units at an urban hospital were surveyed. The 63-item survey included 2 previously validated scales, demographic questions, and opinion questions.

Results
Nurses’ self-confidence and perceived benefit of family presence were significantly related (r = 0.54; P &lt; .001). Self-confidence was significantly greater in nurses who had completed training in Advanced Cardiac Life Support, had experienced 10 or more resuscitation events, were specialty certified, or were members of nurses’ professional organizations. Barriers to family presence included fear of interference by the patient’s family, lack of space, lack of support for the family members, fear of trauma to family members, and performance anxiety.

Conclusions
Changing the practice of family presence will require strengthening current policy, identifying a team member to attend to the patient’s family during resuscitation, and requiring nurses to complete education on evidence that supports family presence and changes in clinical practice.
Nocturnal enuresis: A topic review and institution experience
Authors: DiBianco John Michael , Morley Chad , Al-Omar Osama 
Published: November 2014

AbstractThe objective is to provide a review of nocturnal enuresis (NE), including its epidemiology, etiology, pathophysiology, evaluation, and current management. We also set to provide further insight on the treatment of this condition from the experience derived from patients cared for at our tertiary‑care institution. NE affects approximately 15% of all children at 5‑year‑old, affecting boys more frequently than girls. At our large university tertiary pediatric urology center, NE and incontinence, in general, is one the most common chief complaints prompting urologic care. In this review, we examine the condition in detail, highlighting specific goals of the initial evaluation and treatment. We contrast the commonly implemented treatment recommendations, available from the literature with strategies we have found valuable from our extensive experience in treating patients with this disorder. Using current urologic reference textbooks, book chapters, Medline, journal articles and reviews describing the many aspects of NE were reviewed in order to describe NE and the current practices at our institution. Although, this is not a systematic literature review, it includes relevant available research, institutional experience and urological expert opinion and current practices at a tertiary state health facility. The treatment of NE remains a challenge for many pediatricians and pediatric urologists. This likely stems from the multiple possible etiologies of the disorder. We have established a treatment algorithm at our institution, which we have found successful in the majority of our patients. This consists of starting patients on urotherapy, then offering both the enuresis alarm device and medication therapy as first line treatments, and finally adding anticholingerics for combination therapy. Our hope is with further research the treatment of NE will continue to improve.
Unique mitral valve mass: Think beyond vegetation
Authors: Farhoud Mahmoud , Bakdash Husam 
Published: November 2014

AbstractOsteosarcoma is a rare cardiac malignant tumor. This case of cardiac osteosarcoma presented with atrial fibrillation. Initial echocardiogram demonstrated mitral valve echodensity and mitral valve regurgitation. Surgery and histopathological examination identified the tumor as an osteosarcoma. Tumor grade appeared to be prognostically important in cardiac sarcoma, with poor prognosis in high-grade tumors.
The Satyagraha against diabetes
Authors: Kalra Sanjay , Baruah Maanash , Saboo Banshi 
Published: November 2014

AbstractThis communication discusses Gandhian thought, i.e, the philosophy propounded by Mahatma Gandhi, and its relevance to modern diabetes care. The authors call for a ′righteous movement′ against diabetes, including individual and community-based efforts to minimize its impact. They list various useful suggestions which are concordant with Gandhian thought, and suggest interventions which the Mahatma would have supported in the fight against diabetes. Ideas and thoughts published by him are cited to back these suggestions.
The second step in data analysis: Coding qualitative research data
Authors: Stuckey Heather 
Published: November 2014

AbstractCoding is a process used in the analysis of qualitative research, which takes time and creativity. Three steps will help facilitate this process:1. Reading through the data and creating a storyline;2. Categorizing the data into codes; and3. Using memos for clarification and interpretation.Remembering the research question or storyline, while coding will help keep the qualitative researcher focused on relevant codes. A data dictionary can be used to define the meaning of the codes and keep the process transparent. Coding is done using either predetermined (a priori) or emergent codes, and most often, a combination of the two. By using memos to help clarify how the researcher is constructing the codes and his/her interpretations, the analysis will be easier to write in the end and have more consistency. This paper describes the process of coding and writing memos in the analysis of qualitative data related to diabetes research.
Diabetes mellitus: Implication in rural area of Thane district, India
Authors: Bansode-Gokhe Seema , Waghmare Rakesh , Ratnendra Ratnerdra 
Published: November 2014

Abstract
Context: Diabetes mellitus along with its complications contribute a significant amount of burden on the society. Lack of awareness has resulted in an increased number of diabetics over the years. Aims: To study the sociodemographic status, complication profile and perception of diabetic patients regarding their illness. Settings and Design: Cross sectional center based study done on 110 type 2 diabetic patients over a period of 5 months at rural health training center. Materials and Methods: Universal sampling technique was used. All old and newly diagnosed diabetic patients were interviewed by Face to Face interview method. Statistical Analysis: Descriptive statistics for sociodemographic factors and morbidity; cross tabulation by using test of significance to find association between different variables were used. Results: 50% patients were illiterate, 91.82% were married and 44.5% were farmers. The perception of self-health was reported GOOD on Stanford patient education research center questionnaire scale in 62.7% patients; these responses were significantly associated with males. 61.81% patient had symptoms of coronary heart disease (CHD). 87.3%, 59.1%, and 58.2% patient had symptoms of neuropathy, nephropathy and retinopathy respectively. Out of 61 patients who were aware of complications only 1/10th were aware with the fact that diabetes can affect eye and heart. Conclusions: Almost half patients were unaware that disease is associated with complications and in remaining halves awareness was negligible for neuropathy and nephropathy. In contrast around 2/3rd patients had symptoms of CHD, nephropathy and retinopathy.
Feasibility of opportunistic screening for type 2 diabetes mellitus: Need for interventions to improve follow up
Authors: Shewade Hemant , Palanivel Chinnakali , Balamurugesan Kandan , Vinayagamoorthi Ramu , Sunderamurthy Bhuvaneswary , Vasudevan Kavita , Basu Sharbari , Rajagopalan Narayana 
Published: November 2014

Abstract
Objective: To determine the feasibility of opportunistic screening for type 2 diabetes (T2DM) among adult attendees of medicine outpatient department (OPD) at a tertiary care hospital in Puducherry district, India. Materials and Methods: A hospital-based cross-sectional study was conducted among nonpregnant nondiabetic adults above 30 years of age attending MOPD to screen for diabetes mellitus (DM). Those with random blood glucose of 6.1 mM/l or more were sent for definitive tests; fasting plasma glucose and post prandial (PP) plasma glucose. Double data entry and validation was done. Results: A total of 510 outpatients were tested for random blood glucose: 278 (54.5%) had blood glucose above the cut off. Out of 278, 83 (29.9%) returned for definitive tests: 18 [21.7%, 0.95 CI: 14.2%, 31.7%] had either fasting plasma glucose and/or PP plasma glucose in diabetic range and 16 (19.3%, 0.95 CI: 12.2%, 29.1%) had impaired fasting glucose and/or impaired glucose tolerance. Case detection (screening yield) of diabetes in the adult outpatients was 3.5% (0.95 CI: 2.2%, 5.5%). Conclusion: Compliance or follow-up for definitive tests was poor resulting in low screening yield. Future studies should focus on interventions to improve follow up of outpatients.
Pilot study on the effectiveness of telemedicine in improving the quality of diabetes care of the rural Nepal
Authors: Bhattarai Jyoti , Shakya Samjhana , Shrestha Niraj 
Published: November 2014

AbstractThe use of telecommunication in the field of medicine is very limited in Nepal. Despite huge potential of improving access of the sub-urban and rural communities with the urban-based health care professionals for expert consultation, the use of the telecommunication technology remains largely unexplored. In light of the facts, a comparative study was conducted at a rural community in Makwanpur. In total 40 patients (20 in each group) were selected for the study with an objective to test the feasibility and effectiveness of telemedicine in improving the quality of diabetes care in an experimental group and control group in Makwanpur district. In the intervention group, diabetes care was provided with tele-consultation for diabetes care mediated via local doctor. The outcome was compared with a control group based in an urban community with treatment as usual in their community. The study results showed that the use of telemedicine is a feasible alternative to provide diabetes care in rural Nepal. Overall fasting blood sugar was better controlled in the control group whereas there was significant improvements in micro albumin were observed in the interventional group. Similarly, the knowledge of the respondents on various aspects of the disease was also found to be better in the interventional group than in the control group. Majority of the respondents (90%) felt telemedicine service is less expensive than the service they had taken before.
From Ethnocentrism to Transculturalism: A Film Studies Pedagogical Journey
Authors: Yeates Helen , McVeigh Margaret , Van Hemert Tess 
Published: November 2014

This study reviews the exploratory implementation of an ‘internationalising the curriculum’ policy in relation to a cultural studies unit within a Creative Industries Faculty at an Australian university. Charting certain pedagogical practices in the delivery of transnational film studies, this case study involves a critical, contextual examination of student feedback as well as current theories about transcultural curricula in general and film studies curricula in particular. The study shows that tertiary students can be provided with an extraordinarily rich range of differing, sometimes conflicting, but always engaging transcultural insights and understandings. It is further argued that transnational competencies may be developed and enabled through the innovative realisation of a type of ‘border crossing’ pedagogical model, largely by foregrounding transcultural ‘affective’ issues around social justice.
Inflammation and repair in the ischaemic myocardium
Authors: Swirski F. K. 
Published: November 2014

SummaryShortly after myocardial infarction, various circulating leukocyte subsets accumulate in the heart. Leukocyte recruitment is highly coordinated and relies on cell production in the bone marrow, mobilization to the blood, and chemokine-mediated infiltration to the destination tissue. Neutrophils, which are phagocytic and inflammatory, are among the first leukocytes to accumulate in large numbers. Within a day, neutrophils disappear and are replaced by a subset of monocytes that further contribute to inflammation and phagocytosis. After a few days, monocyte-derived reparative macrophages accrue, quell inflammation, and foster angiogenesis and tissue remodelling. Studies suggest a wellbalanced response comprising these three waves is essential to optimal infarct healing.