bluuebunny/crossref_metadata_2025_split huggingface dataset:
An analysis of relationships among transformational leadership, job satisfaction, organizational commitment and organizational trust in two Turkish hospitals
Authors: Top Mehmet , Tarcan Menderes , Tekingündüz Sabahattin , Hikmet Neşet 
Published: December 2012

SUMMARYThe purpose of this study was to investigate the relationships among employee organizational commitment, organizational trust, job satisfaction and employees' perceptions of their immediate supervisors' transformational leadership behaviors in Turkey. First, this study examined the relationships among organizational commitment, organizational trust, job satisfaction and transformational leadership in two Turkish public hospitals. Second, this investigation examined how job satisfaction, organizational trust and transformational leadership affect organizational commitment. Moreover, it was aimed to investigate how organizational commitment, job satisfaction and transformational leadership affect organizational trust. A quantitative, cross‐sectional method, self‐administered questionnaire was used for this study. Eight hundred four employees from two public hospitals in Turkey were recruited for collecting data. The overall response rate was 38.14%. The measurement instruments of survey were the Job Satisfaction Survey (developed by P. Spector), the Organizational Commitment Questionnaire (developed by J. Meyer and N. Allen), the Organizational Trust Inventory‐short form (developed by L. Cummings and P. Bromiley) and the Transformational Leadership Inventory (TLI) (developed by P. M. Podsakoff). Five‐point Likert scales were used in these measurement instruments. Correlation test (the Pearson's rank test) was used to examine relationships between variables. Also, multiple regression analysis was used to determine the regressors for organizational commitment and organizational trust. There were significant relationships among overall job satisfaction, overall transformational leadership and organizational trust. Regression analyses showed that organizational trust and two job satisfaction dimensions (contingent rewards and communication) were significant predictors for organizational commitment. It was found that one transformational leadership dimension (articulating a vision), two job satisfaction dimensions (pay and supervision) and two organizational commitment dimensions (affective commitment and normative commitment) were significant regressors for organizational trust. There is a lack of research in the health organizations regarding organizational commitment, organizational trust, job satisfaction and transformational leadership. The investigator of the proposed study intends to add to the literature and intends to prove that the proposed study would be important for healthcare organizations. A number of specific measures should be undertaken to reduce factors that negatively affect organizational commitment, organizational trust and job satisfaction of hospital personnel and to improve transformational leadership behaviors of hospital administrators. Copyright © 2012 John Wiley & Sons, Ltd.
Pain coping and acceptance as longitudinal predictors of health‐related quality of life among people with haemophilia‐related joint pain
Authors: Elander J. , Morris J. , Robinson G. 
Published: December 2012

AbstractBackgroundInterventions based on coping and acceptance can be adapted for people with different painful conditions. Evidence about baseline characteristics that predict improved outcomes is informative for matching people to interventions, whereas evidence about changes that predict improved outcomes is informative about the processes that interventions should target.MethodsParticipants in a low‐intensity programme to promote self‐management of haemophilia‐related chronic joint pain (n = 101) reported pain intensity, coping, acceptance and quality of life at baseline and 6‐month follow‐up. Baseline and change measures of pain intensity, coping and acceptance were used to predict follow‐up quality of life, taking account of baseline quality of life.ResultsChanged (reduced) pain intensity predicted better physical quality of life, independently of age, haemophilia severity, baseline pain intensity and baseline physical quality of life. Lower baseline passive coping and changed (increased) pain acceptance predicted better mental quality of life, independently of age, severity and baseline mental quality of life. Increased activity engagement but not pain willingness predicted better mental quality of life when pain acceptance was decomposed. Changed (reduced) negative thoughts also predicted better mental quality of life when separate acceptance subscales were used. Active pain coping did not predict physical or mental quality of life.ConclusionsInitially high levels of passive coping may be an obstacle to improving mental quality of life. Acceptance rather than coping may be a more useful behavioural change target, but more research is needed about the meanings and therapeutic implications of different elements of pain acceptance.
Hyperspectral multimodal CARS microscopy in the fingerprint region
Authors: Pegoraro Adrian F. , Slepkov Aaron D. , Ridsdale Andrew , Moffatt Douglas J. , Stolow Albert 
Published: December 2012

AbstractA simple scheme for multimodal coherent anti‐Stokes Raman scattering (CARS) microscopy is based on the spectral focusing of ultrafast‐oscillator‐derived pump/probe light and synchronous photonic crystal fiber (PCF) fiber‐generated broadband Stokes light. To date, such schemes allowed rapid hyperspectral imaging throughout the CH/OH high frequency region (2700–4000 cm‐1). Here we extend this approach to the middle (1640–3300 cm‐1) and fingerprint regions (850–1800 cm‐1) of the Raman spectrum. Our simple integrated approach to rapid hyperspectral CARS microscopy in the fingerprint region is demonstrated by applications to label‐free multimodal imaging of cellulose and bulk bone, including use of the phosphate resonance at 960 cm‐1. (© 2014 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Prenatal stress disturbs hippocampal KIF17 and NR2B in spatial cognition in male offspring
Authors: Zhao Depeng , Liu Dan , Chen Xueyu , Wang Kai , Zhang Ai , Kang Jiuhong , Zhou Qian , Duan Tao 
Published: December 2012

AbstractNumerous studies have demonstrated that prenatal stress disturbs the hippocampal‐mediated learning and memory processes in offspring. The underlying mechanisms for this effect, however, remain vague. It is well documented that N‐methyl‐D‐aspartate (NMDA) receptors play a pivotal role in learning and memory, which are related to dynamically trafficking and regulating NMDA receptors by their response motor proteins. Over the past few years, increasing numbers of studies have elucidated that hippocampal‐mediated learning and memory are regulated by KIF17 (kinesin superfamily motor protein 17), which specifically transports and regulates the NMDA receptor subunit NR2B in hippocampal neurons. The present study shows the influence of prenatal stress on KIF17 and NR2B expression and hippocampal NR2A/NR2B ratio partially reflecting function of KIF17, using mice as models. It was found that prenatal stress significantly decreased the hippocampal KIF17 and NR2B level in offspring at postnatal stages of 3 weeks and 9 weeks. Moreover, hippocampal KIF17 in the prenatally stressed pups continued to be weakened even after serial Morris water maze trainings, but not NR2B. Finally, the synaptic NR2A/NR2B level was upregulated in offspring exposed to prenatal stress, which revealed the dysfunction of KIF17. Thus, we conclude that prenatal stress leads to long‐lasting deterioration of the expression and function of hippocampal KIF17 in offspring, which may be related to deficits of spatial cognition caused by prenatal stress. These data underpin the hypotheses that a physiopathology of neurodevelopmental origin in early life leads to defects in learning and memory in later life. © 2012 Wiley Periodicals, Inc.
Serial cerebrospinal fluid neurofilament heavy chain levels in severe Guillain‐Barré syndrome
Authors: Dujmovic Irena , Lunn Michael P. , Reilly Mary M. , Petzold Axel 
Published: December 2012

ABSTRACTIntroductionProximal axonotmesis results in the release of neurofilament (Nf) proteins into the cerebrospinal fluid (CSF) in patients with Guillain‐Barré syndrome (GBS). High CSF levels of the phosphorylated form of Nf‐heavy chain (NfHSMI35) at GBS onset have been reported to be a poor prognostic marker, but routine measurement of CSF NfHSMI35 levels has not been done and the longitudinal profile of CSF NfHSMI35 levels in GBS is not known.MethodsThis prospective case series describes the clinical, neurophysiological, and biomarker characteristics of 3 patients with severe GBS.ResultsHigh and increasing levels of CSF NfHSMI35 in serial CSF samples were associated with poor clinical and electrophysiological outcome.ConclusionsThese data further suggest that CSF NfHSMI35 could be a prognostic biomarker which might indicate the development of retrograde axonal degeneration or additional proximal axonal damage during the course of GBS. Muscle Nerve, 2013
Seasonal variation in prevalence of carpal tunnel syndrome
Authors: Scalco Renata Siciliani , Pietroski Franciane , Celli Luiz Felippe S. , Gomes Irenio , Becker Jefferson 
Published: December 2012

ABSTRACTIntroduction: The influence of cold temperatures on neuropathies has been reported previously, but its impact on carpal tunnel syndrome (CTS) is not well analyzed. Methods: We analyzed the frequency of CTS among neurophysiological evaluations according to seasonal variation in 9574 consecutive patients (4260 with CTS). Results: A higher frequency of CTS was found in the winter (50.8%), and the lowest number for CTS diagnosis was found in the summer (38.9%). In both autumn and spring the prevalence remained stable at an intermediate level between summer and winter at 42.8% and 43.5%, respectively. Conclusion: CTS frequency was much higher in winter in this center. Muscle Nerve 47: 925–927, 2013
Mast cells can regulate skeletal muscle cell proliferation by multiple mechanisms
Authors: Duchesne Elise , Bouchard Patrice , Roussel Marie‐Pier , Côté Claude H. 
Published: December 2012

ABSTRACTIntroduction: Mast cells (MCs) can stimulate cell proliferation, but their specific contribution to skeletal muscle regeneration is not well defined. Methods: L6 myoblast proliferation was assessed in coculture with MCs or when grown with MC‐conditioned media. To address the in vivo implication of MCs in regeneration, rats were treated with cromolyn, and myoblast proliferation, immune cell accumulation, and myogenic factors were assessed in bupivacaine‐injured muscles. Results: In vitro, both procedures increased the L6 cell proliferation rate, and this was tryptase‐dependent. In vivo, MC stabilization increased myoblast proliferation and accumulation of macrophages CD68 and CD163 after injury. This correlated with a sequential increase in MyoD and myogenin protein level expression. Conclusions: MCs can directly stimulate muscle cell proliferation via tryptase. MCs can influence myoblast proliferation in vivo, but this effect seems to be predominantly related to their modulation of macrophage recruitment. The MC is a potential actor in the early stages of muscle healing. Muscle Nerve 48: 403–414, 2013
Study of bond stress–slip relationship and radial dilation in prestressed concrete
Authors: Benítez José Mª , Gálvez J.C. , Casati M.J. 
Published: December 2012

SUMMARYThis paper presents two test procedures for evaluating the bond stress–slip and the slip–radial dilation relationships when the prestressing force is transmitted by releasing the steel (wire or strand) in precast prestressed elements. The bond stress–slip relationship is obtained with short length specimens, to guarantee uniform bond stress, for three depths of the wire indentation (shallow, medium and deep). An analytical model for bond stress–slip relationship is proposed and compared with the experimental results. The model is also compared with the experimental results of other researchers. Since numerical models for studying bond‐splitting problems in prestressed concrete require experimental data about dilatancy angle (radial dilation), a test procedure is proposed to evaluate these parameters. The obtained values of the radial dilation are compared with the prior estimated by numerical modelling and good agreement is reached. Copyright © 2012 John Wiley & Sons, Ltd.
Control of the preferred orientations of Cu(In,Ga)Se2 films and the photovoltaic conversion efficiency using a surface‐functionalized molybdenum back contact
Authors: Yoon Ju‐Heon , Kim Won‐Mok , Park Jong‐Keuk , Baik Young‐Joon , Seong Tae‐Yeon , Jeong Jeung‐hyun 
Published: December 2012

ABSTRACTThe surface microstructures of molybdenum (Mo) back contacts were shown to play a crucial role in the preferred orientations of Cu(In,Ga)Se2 (CIGS) films. The lower surface density of Mo tends to drive the growth of CIGS films toward favoring a (220)/(204) orientation, attributed to the higher likelihood of a MoSe2 reaction. This work showed that the presence of a very thin layer on a Mo bilayer facilitated the tuning of the CIGS grain orientations from strongly favoring (112) to strongly favoring (220)/(204) without sacrificing the electrode conductivity. The efficiency of Na‐doped CIGS cells was increased toward decreasing Mo surface density, that is, increasing (220)/(204) CIGS orientation. Although slight changes in Na doping found between different Mo surface properties could contribute in part, the comparison with Na‐reduced CIGS cells showed that it was more likely due to the (220)/(204) orientation‐related enhancement of CdS/CIGS junction characteristics, which were possibly attributed to a favorable CdS reaction and a reduction in the defect metastabilities. Copyright © 2012 John Wiley & Sons, Ltd.
Temperature influence on performance degradation of hydrogenated amorphous silicon solar cells irradiated with protons
Authors: Sato Shin‐ichiro , Sai Hitoshi , Ohshima Takeshi , Imaizumi Mitsuru , Shimazaki Kazunori , Kondo Michio 
Published: December 2012

ABSTRACTThis paper reports temperature influence on radiation degradation of hydrogenated amorphous silicon (a‐Si : H) solar cells. Degradation behaviors of a‐Si : H solar cells irradiated with protons at 331 K are compared with that at 298 K (room temperature). Variations with time in the post‐irradiation electrical properties are also investigated. It is found that the radiation degradation of the electrical properties at 331 K is significantly smaller than that at room temperature. Also, all the electrical properties (short‐circuit current, open‐circuit voltage, output maximum, and fill factor) recover with time after irradiation even at room temperature. The characteristic time of thermal annealing of short‐circuit current is larger as the temperature is higher. These results indicate that temperature during irradiation and elapsed time from irradiation to measurement is an important parameter for radiation degradation of a‐Si : H solar cells. Therefore, these parameters should be controlled in conducting the ground radiation tests. Copyright © 2012 John Wiley & Sons, Ltd.
A longitudinal study of distress (depression and anxiety) up to 18 months after radiotherapy for head and neck cancer
Authors: Neilson Kate , Pollard Annabel , Boonzaier Ann , Corry June , Castle David , Smith David , Trauer Tom , Couper Jeremy 
Published: December 2012

AbstractObjectiveThe aim of the study was to assess symptoms of depression and anxiety in patients with head and neck cancer up to 18 months after radiotherapy.MethodsProspective observational study of consecutive head and neck outpatients was conducted at a tertiary cancer centre (n = 101). Eligibility included diagnosis of cancer in the head and neck region, where the patient agreed to radiotherapy with curative intent. Data were collected before commencement of radiotherapy and 3 weeks and 18 months after completion. Symptoms of depression and anxiety were assessed by the Hospital Anxiety and Depression Scale. Tumour/treatment‐related physical symptoms were assessed using the ‘Additional Concerns’ subscale of the Functional Assessment of Chronic Illness Therapy for Head and Neck Cancer.ResultsThe prevalence of identified probable cases of depression was 15% at baseline, increasing to 29% 3 weeks post‐treatment, falling to 8% at 18‐month follow‐up. The number of probable cases of anxiety was 20% at baseline, 17% at 3 weeks post‐treatment and 22% at 18‐month follow‐up. Depression scores significantly increased from baseline to 3 weeks post‐treatment and decreased at 18‐month follow‐up. Variability in depression scores was accounted for by tumour/treatment‐related physical symptoms. Anxiety scores significantly decreased between baseline and 3‐week post‐treatment and increased at 18‐month follow‐up. Younger age and more tumour/treatment‐related physical symptoms predicted anxiety scores.ConclusionsThe rates of depression in head and neck cancer patients increase following cancer treatment and are related to tumour/treatment‐related physical symptoms. Anxiety levels are higher pre‐treatment, lower immediately following cancer treatment but rise to near pre‐treatment levels more than a year after completion of cancer treatment. Copyright © 2012 John Wiley & Sons, Ltd.
Protein prosthesis: β‐peptides as reverse‐turn surrogates
Authors: Arnold Ulrich , Huck Bayard R. , Gellman Samuel H. , Raines Ronald T. 
Published: December 2012

AbstractThe introduction of non‐natural modules could provide unprecedented control over folding/unfolding behavior, conformational stability, and biological function of proteins. Success requires the interrogation of candidate modules in natural contexts. Here, expressed protein ligation is used to replace a reverse turn in bovine pancreatic ribonuclease (RNase A) with a synthetic β‐dipeptide: β2‐homoalanine–β3‐homoalanine. This segment is known to adopt an unnatural reverse‐turn conformation that contains a 10‐membered ring hydrogen bond, but one with a donor–acceptor pattern opposite to that in the 10‐membered rings of natural reverse turns. The RNase A variant has intact enzymatic activity, but unfolds more quickly and has diminished conformational stability relative to native RNase A. These data indicate that hydrogen‐bonding pattern merits careful consideration in the selection of beneficial reverse‐turn surrogates.
Theoretical study of the initial stage of InN growth on cubic zirconia (111) substrates
Authors: Guo Yao , Inoue Shigeru , Kobayashi Atsushi , Ohta Jitsuo , Fujioka Hiroshi 
Published: December 2012

AbstractAn initial stage of InN growth on cubic zirconia (111) substrates has been investigated using first‐principles calculations based on density functional theory (DFT). We have evaluated adsorption energies of indium and nitrogen atoms on cubic zirconia (111) surfaces, and have found that the differences in the adsorption energies of the indium atoms at various adsorption sites were small, indicating that the migration of the indium atoms on zirconia (111) surfaces occurs readily. On the other hand, we have found that the differences in the adsorption energies of the nitrogen atoms at various adsorption sites were large, implying that the nitrogen atoms tend to stay at the stable site with the largest adsorption energy, which was identified as the O–Zr bridge site. These results suggest that the first layer of InN films is the nitrogen layer. In addition, we have found that the energetically favorable arrangement is comprised of InN(0001)//cubic zirconia (111) and InN $ [11\bar 20] $//cubic zirconia $ [1 \bar 10], $ which is quite consistent with previously obtained experimental data. Furthermore, the hybridization effect between N 2p and O 2p plays a crucial role in determining the interface structure for the growth of InN on cubic zirconia (111) surfaces. (© 2012 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Hepatitis B and C in liver transplantation: new strategies to combat the enemies
Authors: Beckebaum Susanne , Kabar Iyad , Cicinnati Vito R. 
Published: December 2012

SUMMARYHepatitis B immune globulin‐free therapeutic regimens with a nucleos(t)ide analogue (NUC) or NUC combinations after liver transplantation (LT) are currently being investigated for their efficacy and safety as HBV re‐infection prophylaxis in clinical studies. Recurrence rates differ among these studies as most of them are limited by a non‐randomised study design, small sample size, lack of long‐term data and varying time intervals for the switch from combined to purely virostatic prophylaxis.Post‐transplant pre‐emptive antiviral therapy with pegylated IFN and ribavirin is associated with low sustained virological response rates and was found to have no advantage over treatment of manifest HCV re‐infection. Safety and efficacy of triple antiviral therapy including boceprevir or telaprevir in patients with manifest HCV re‐infection are currently under investigation in clinical trials. Relevant drug interactions have been shown to occur during calcineurin inhibitor (CNI) and concomitant triple antiviral therapy, which vary with type of CNI and choice of HCV protease inhibitor. Newer direct‐acting antivirals with lower or minimal toxicity, when used in combination with immunosuppressives, are worthy of further study in LT patients.This review focuses on hot topics in the management of hepatitis B and C patients before and after LT and offers a critical summarised selection of the corresponding relevant studies published in the current literature or presented at recent liver congresses. Copyright © 2012 John Wiley & Sons, Ltd.
Adaptive regulation for linear systems with multiple zeros at the origin
Authors: Isidori A. , Marconi L. 
Published: December 2012

SUMMARYWe consider the problem of asymptotic rejection of exogenous harmonic inputs having unknown amplitudes, phases, and frequencies on the output for a class of uncertain and nonminimum‐phase linear systems. Special emphasis is given to the case in which the controlled system has multiple zeros at the origin. It is shown how the method recently proposed to design internal models by means of regression arguments, combined with control strategies based on the redesign of the zero dynamics of the system through redefinition of the output, can be successfully used to solve the problem in presence of plant parameter uncertainties.Copyright © 2012 John Wiley & Sons, Ltd.