bluuebunny/crossref_metadata_2025_split huggingface dataset:
Consumer Acceptability and Sensory Profile of Cooked Broccoli with Mustard Seeds Added to Improve Chemoprotective Properties
Authors: Ghawi Sameer Khalil , Shen Yuchi , Niranjan Keshavan , Methven Lisa 
Published: August 2014

AbstractBroccoli, a rich source of glucosinolates, is a commonly consumed vegetable of the Brassica family. Hydrolysis products of glucosinolates, isothiocyanates, have been associated with health benefits and contribute to the flavor of Brassica. However, boiling broccoli causes the myrosinase enzyme needed for hydrolysis to denature. In order to ensure hydrolysis, broccoli must either be mildly cooked or active sources of myrosinase, such as mustard seed powder, can be added postcooking. In this study, samples of broccoli were prepared in 6 different ways; standard boiling, standard boiling followed by the addition of mustard seeds, sous vide cooking at low temperature (70 °C) and sous vide cooking at higher temperature (100 °C) and sous vide cooking at higher temperature followed by the addition of mustard seeds at 2 different concentrations. The majority of consumers disliked the mildly cooked broccoli samples (70 °C, 12 min, sous vide) which had a hard and stringy texture. The highest mean consumer liking was for standard boiled samples (100 °C, 7 min). Addition of 1% mustard seed powder developed sensory attributes, such as pungency, burning sensation, mustard odor, and flavor. One cluster of consumers (32%) found mustard seeds to be a good complement to cooked broccoli; however, the majority disliked the mustard‐derived sensory attributes. Where the mustard seeds were partially processed, doubling the addition to 2% led to only the same level of mustard and pungent flavors as 1% unprocessed seeds, and mean consumer liking remained unaltered. This suggests that optimization of the addition level of partially processed mustard seeds may be a route to enhance bioactivity of cooked broccoli without compromising consumer acceptability.
Long‐term allergic dermatitis caused by sevoflurane: a clinical report
Authors: LLORÉNS HERRERIAS J. , DELGADO NAVARRO C. , BALLESTER LUJÁN M. T. , IZQUIERDO PALOMARES A. 
Published: August 2014

BackgroundAllergy to volatile anaesthetics is extremely rare, but capable of damaging the professional career.MethodsThis article presents the case of a 60‐year‐old surgeon who developed a skin rash on the reverse of hands, which progressively worsened and extended to distant fold areas. Blood tests were normal but for eosinophilia and risen total IgE, with normal specific globulins and skin prick tests for common allergens. After 8 years, a malfunction in the anaesthetic gas scavenging system was found, and symptoms remitted within a week following its replacement. Repeated open application test with sevoflurane led to the appearance of the same lesions in the tested areas and in distant body folds.ResultsWe hypothesize that the most probable mechanism for the reaction in our patient is systemic allergic contact dermatitis, which is caused by repeated systemic exposure to a hapten that reaches the skin through haematogenous transport in a sensitized patient.ConclusionsThe report aims to warn about the potential aetiological relationship between exposure to inhaled anaesthetics and allergic manifestations with cutaneous symptoms.
Valuation of Long‐Maturity KIKO Options Under the Stochastic Volatility Model
Authors: Lee Joon‐Haeng , Song Junmo 
Published: August 2014

AbstractThis paper explores the valuation of KIKO currency options under the stochastic volatility (SV) model. In particular, Heston's (Review of Financial Studies, 6, 1993, 327) SV model is adopted to price two types of KIKO options. The paper proposes the iterated feasible two‐step estimation method, a technique for estimating the parameters in Heston's (Review of Financial Studies, 6, 1993, 327) model. Given constant fluctuations in volatility over time and the relatively long maturity of KIKO options, the SV model is more appropriate for evaluating long‐maturity KIKO options, the value of which depends heavily on volatility estimates for the constant‐volatility (CV) model. The results indicate that KIKO options considered in this paper are less attractive under the SV model than under the CV model, although it remains unclear whether the options are significantly overpriced.
Evaluation of a copro‐antigenELISAto detectFasciola hepaticainfection in sheep, cattle and horses
Authors: Palmer DG , Lyon J , Palmer MA , Forshaw D 
Published: August 2014

ObjectiveTo determine the specificity and sensitivity of a commercial copro‐antigenELISAfor the detection ofFasciola hepaticainfection in cattle and sheep and to assess the suitability of the test for use in horses.MethodsTesting was done on more than 100 negative faecal samples from each of sheep, cattle and horses and on at least 40 positive faecal samples from each species. Positive samples were selected based on a positive sedimentation test for liver fluke eggs. Faecal samples of animals fromWesternAustralia, which is free of liver fluke infection, served as negative controls. Specificity and sensitivity were assessed for each species using the recommended kit cut‐off and also custom cut‐offs specific for each species based on the mean plus 3‐fold standard deviation of the mean of the negative samples for each species.ResultsUsing the cut‐off recommended by the kit manufacturer, the specificity was 100% for all species and the sensitivity was 88%, 80% and 9% for sheep, cattle and horses, respectively. Using the lower custom cut‐offs for each species improved the sensitivity to 100% for sheep, 87% for cattle and 28% for horses, while maintaining the specificity above 99% for all species.ConclusionsThe sensitivity of the commercial copro‐antigenELISAcan be improved by using custom cut‐off values for each species. With this modification, it is a suitable alternative screening test to the currently used sedimentation test for border control of sheep and cattle movement. The test is not suitable for use in horses.
Patient‐specific determinants of responsiveness to robot‐enhanced treadmill therapy in children and adolescents with cerebral palsy
Authors: Schroeder Andreas Sebastian , Von Kries Rüdiger , Riedel Christina , Homburg Maria , Auffermann Helene , Blaschek Astrid , Jahn Klaus , Heinen Florian , Borggraefe Ingo , Berweck Steffen 
Published: August 2014

AimThe aim of the study was to evaluate patient‐specific determinants of responsiveness to robot‐enhanced repetitive treadmill therapy (ROBERT) in patients with early‐developed movement disorders.MethodPatients were treated over 12 sessions during a 3‐week period. Gross Motor Function Measure‐66 (GMFM‐66) scores 1 day before ROBERT were compared with scores recorded 1 day after ROBERT. The association of GMFM‐66 baseline score, age, sex, aetiology, and add‐on botulinum toxin therapy to response to treatment was assessed.ResultsEighty‐three patients aged between 4 and 18 years (48 males, 35 females; mean age 10y 8mo, SD 6y 1mo; Gross Motor Function Classification System level I [n=12], II [n=21], III [n=35], IV [n=10], and V [n=1]) were each treated for a total of 7.2 (SD 1.9) treadmill walking hours. Aetiology was bilateral spastic cerebral palsy (BS‐CP; n=69), unilateral CP (n=3), ataxic CP (n=3), hereditary spastic paraparesis (n=6), and genetic syndrome including spasticity (n=2). Meaningful improvements were observed in GMFM‐66 (+2.5; 95% CI 2.0–3.0), GMFM‐D (+5.2; 95% CI 3.6–6.8), and GMFM‐E (+4.0; 95% CI 2.8–5.3). There was a high inter‐individual variability in treatment response. After multivariable adjustment, the improvements in GMFM‐66 and GMFM‐E scores were positively associated with the GMFM‐66 baseline score. The effect on GMFM‐D improvement was inversely associated with age.InterpretationGross motor abilities at baseline and age were identified as relevant determinants for the high degree of interpersonal variability in response to ROBERT.
Endocrine function over time in patients with myotonic dystrophy type 1
Authors: Dahlqvist J. R. , Ørngreen M. C. , Witting N. , Vissing J. 
Published: August 2014

Background and purposePatients with myotonic dystrophy type 1 (DM1) have an increased incidence of endocrine dysfunction. In this study, the temporal evolution of endocrine dysfunction in patients withDM1 was investigated.MethodsEndocrine function was assessed in 68 patients withDM1, in whom endocrine function had been followed, on average, for 8 years. The endocrine function was assessed by measuring the concentration of hormones and metabolites in blood and by validating libido with questionnaires.ResultsAt baseline, 30 of the 68 patients presented with at least one hormonal dysfunction. When re‐evaluated after 8 years, 57 of 68 patients had endocrine dysfunction. Diabetic patients had increased from one to four. At follow‐up, hyperparathyroidism occurred in 25% and abnormal thyroid‐stimulating hormone in 21%, compared with 14% and 9% at baseline. Sixteen of 33 men had increased luteinizing hormone levels compared with seven at baseline.ConclusionsOur findings show that endocrine abnormalities amongst patients withDM1 increase over time. Based on these findings it is suggested that correctable endocrine abnormalities should be monitored periodically in this patient group.
Associations of chronic heart failure with outcome in acute ischaemic stroke patients who received systemic thrombolysis: analysis from VISTA
Authors: Abdul‐Rahim A. H. , Fulton R. L. , Frank B. , McMurray J. J. V. , Lees K. R. ,   the VISTA collaborators
Published: August 2014

Background and purposeThere are concerns that systemic thrombolysis might not achieve clinically important outcome amongst chronic heart failure (CHF) patients with acute ischaemic stroke. Our aim was to investigate the relevance of CHF on the outcome of acute stroke patients who received thrombolysis.MethodsA non‐randomized cohort analysis was conducted using data obtained from the Virtual International Stroke Trials Archive. The association of outcome amongst CHF patients with thrombolysis treatment was described using the modified Rankin scale (mRS) distribution at day 90, stratified by the presence of atrial fibrillation. Dichotomized outcomes were considered as a secondary end‐point.Results5677 patients were identified, of whom 2366 (41.7%) received thombolysis. Five hundred and three (8.9%) patients had CHF, of whom 209 (41.6%) received thrombolysis. The presence of CHF was associated with a negative impact on overall stroke outcome [odds ratio (OR) 0.73 (95% confidence interval (CI) 0.62–0.87), P < 0.001]. However, thrombolysis treatment was associated with favourable functional outcome using ordinal mRS, irrespective of CHF status, after adjustment for age and baseline National Institutes of Health Stroke Scale [OR 1.44 (95% CI 1.04–2.01, P = 0.029) for CHF patients versus OR 1.50 (95% CI 1.36–1.66, P < 0.001) for non‐CHF patients]. CHF patients had higher mortality at day 90 than non‐CHF patients. There was no significant difference for recurrent stroke or symptomatic intracerebral haemorrhage within 7 days of the initial stroke between CHF and thrombolysis groups.ConclusionsChronic heart failure was associated with a worse outcome with or without thrombolysis. However, acute stroke patients who received thrombolysis had more favourable outcome regardless of CHF status, compared with their untreated peers. Our findings should reassure clinicians considering systemic thrombolysis treatment in hyperacute ischaemic stroke patients with CHF.
A big‐microsite framework for soil carbon modeling
Authors: Davidson Eric A. , Savage Kathleen E. , Finzi Adrien C. 
Published: August 2014

AbstractSoil carbon cycling processes potentially play a large role in biotic feedbacks to climate change, but little agreement exists at present on what the core of numerical soil C cycling models should look like. In contrast, most canopy models of photosynthesis and leaf gas exchange share a common ‘Farquhaur‐model’ core structure. Here, we explore why a similar core model structure for heterotrophic soil respiration remains elusive and how a pathway to that goal might be envisioned. The spatial and temporal variation in soil microsite conditions greatly complicates modeling efforts, but we believe it is possible to develop a tractable number of parameterizable equations that are organized into a coherent, modular, numerical model structure. First, we show parallels in insights gleaned from linking Arrhenius and Michaelis–Menten kinetics for both photosynthesis and soil respiration. Additional equations and layers of complexity are then added to simulate substrate supply. For soils, model modules that simulate carbon stabilization processes will be key to estimating the fraction of soil C that is accessible to enzymes. Potential modules for dynamic photosynthate input, wetting‐event inputs, freeze–thaw impacts on substrate diffusion, aggregate turnover, soluble‐C sorption, gas transport, methane respiration, and microbial dynamics are described for conceptually and numerically linking our understanding of fast‐response processes of soil gas exchange with longer‐term dynamics of soil carbon and nitrogen stocks.
Towards a better understanding of potential impacts of climate change on marine species distribution: a multiscale modelling approach
Authors: Hattab Tarek , Albouy Camille , Lasram Frida Ben Rais , Somot Samuel , Le Loc'h François , Leprieur Fabien 
Published: August 2014

AbstractAimIn this paper, we applied the concept of ‘hierarchical filters’ in community ecology to model marine species distribution at nested spatial scales.LocationGlobal, Mediterranean Sea and the Gulf of Gabes (Tunisia).MethodsWe combined the predictions of bioclimatic envelope models (BEMs) and habitat models to assess the current distribution of 20 exploited marine species in the Gulf of Gabes. BEMs were first built at a global extent to account for the full range of climatic conditions encountered by a given species. Habitat models were then built using fine‐grained habitat variables at the scale of the Gulf of Gabes. We also used this hierarchical filtering approach to project the future distribution of these species under both climate change (the A2 scenario implemented with the Mediterranean climatic model NEMOMED8) and habitat loss (the loss of Posidonia oceanica meadows) scenarios.ResultsThe hierarchical filtering approach predicted current species geographical ranges to be on average 56% smaller than those predicted using the BEMs alone. This pattern was also observed under the climate change scenario. Combining the habitat loss and climate change scenarios indicated that the magnitude of range shifts due to climate change was larger than from the loss of P. oceanica meadows.Main conclusionsOur findings emphasize that BEMs may overestimate current and future ranges of marine species if species–habitat relationships are not also considered. A hierarchical filtering approach that accounts for fine‐grained habitat variables limits the uncertainty associated with model‐based recommendations, thus ensuring their outputs remain applicable within the context of marine resource management.
The germination strategies of widespread annual plants are unrelated to regional climate
Authors: Mayfield Margaret M. , Dwyer John M. , Main Alanna , Levine Jonathan M. 
Published: August 2014

AbstractAimEnvironmentally cued germination and seed banking are strategies employed by annual plants to persist in unpredictable climates. Moreover, such strategies may be key to persistence under more extreme and variable future climates. In regions with a mediterranean climate, cold‐cued germination can allow populations to avoid germinating under unfavourable conditions and seed banks can buffer population growth in the face of inter‐annual climate variability. Using widespread native annual plant species in the California Floristic Province (CFP), we ask: (1) How common are cold‐cued germination and persistent seed banks? (2) Does the prevalence of cold‐cued germination and seed bank maintenance shift predictably with climate? (3) Are germination strategies taxonomically linked?LocationCalifornia, USA.MethodsWe assessed seed bank persistence and temperature‐cued germination in c. 175 populations of 42 species (eight families) from across California in the 2006 growing season. We then tested for evidence that the prevalence of these adaptations correlated with latitude, increasing climate variability and taxonomy.ResultsOnly 19% of populations had significantly cold‐cued seed germination and only 52% of populations had detectable seed banks. There were no significant relationships between the prevalence of cold‐cued germination and any climate factor. Seed banking was significantly more common in regions with warm, dry conditions in the preceding year, but was not related to long‐term climate averages. Variance in temperature‐cued germination was best explained at the species level, with no variance explained by family.Main conclusionsOur results suggest that germination of annual plants in the CFP is dominated by general risk aversion strategies rather than locally adaptive strategies linked to long‐term climate factors. High germination variability within and among populations, coupled with increased seed banking under less favourable conditions, suggests that germination strategies are unlikely to limit this flora's persistence under an increasingly harsh and unpredictable climate.
Physical activity and health outcomes in persons with haemophilia B
Authors: Niu X. , Poon J. L. , Riske B. , Zhou Z.Y. , Ullman M. , Lou M. , Baker J. , Koerper M. , Curtis R. , Nichol M. B. 
Published: August 2014

SummaryRegular participation in physical activity helps to prevent damage and maintain joint health in persons with haemophilia. This study describes self‐reported physical activity participation among a sample of people with haemophilia B in the US and measures its association with health‐related quality of life (HRQoL). Data on 135 participants aged 5–64 years were abstracted from Hemophilia Utilization Group Study Part Vb. The International Physical Activity Questionnaire assessed physical activity among participants aged 15–64 years, and the Children's Physical Activity Questionnaire abstracted from the Canadian Community Health Survey was used for participants aged 5–14 years. SF‐12 was used to measure HRQoL and the EuroQol (EQ‐5D‐3L) was used to measure health status for participants older than 18 years of age. PedsQL was used to measure HRQoL in children aged 5–18 years. Sixty‐two percent of participants in the 15–64 year‐old age cohort reported a high level of physical activity, 29% reported moderate activity and 9% reported low activity. For children aged 5–14 years, 79% reported participating in physical activity for at least 4 days over a typical week. Based on the 2008 Physical Activity Guidelines for Americans, 79% of adults achieved the recommended physical activity level. Multivariable regression models indicated that adults who engaged in a high level of physical activity reported EQ‐5D Visual Analogue Scale (VAS) scores that were 11.7 (P = 0.0726) points greater than those who engaged in moderate/low activity, indicating better health outcomes. Among children, no statistically significant differences in health outcomes were found between high and moderate or low activity groups.
Japanese Debates on Asia and Asianism: A Conceptual Framework
Authors: Avenell Simon 
Published: August 2014

AbstractThis article analyzes discussions about Asia in Japan since the mid‐1980s, offering a conceptual framework for understanding the contours of this debate. The article identifies three normative positions among participants: those advocating the replication of a Japanese model in Asia, those in favor of a genuine community of Asians, and those who see engagement with Asia as the only solution for the country's economic and social problems. The article argues that globalization and regionalization have been key influences in the evolution of the Asia debate in Japan. Indeed, although Japan remains a very insular country in many ways and although political obstacles persist, the growing richness and complexity of the debate over time may indicate a more multidimensional approach to Asia in the country, which sees beyond immediate geopolitical and economic imperatives.
Health care librarians and information literacy: an investigation
Authors: Kelham Charlotte 
Published: August 2014

AbstractUntil relatively recently, the concept of information literacy, and teaching the skills to enable it, was mainly a concern of academic libraries. Now, it is also seen to be of high importance within the context of health care libraries. Health care libraries and librarians can provide crucial support towards the implementation of evidence‐based practice in patient care through both information literacy skills training and by conducting mediated searches on behalf of health care practitioners. This article reports the findings from an investigation conducted by Charlotte Kelham as part of her MA in Librarianship from the University of Sheffield. Her dissertation investigated how health care librarians understand the concept of information literacy, the implications of this for their role and their perceptions around how their role is valued. Charlotte graduated from Sheffield in 2013 and is currently job hunting.AM
A mixed‐methods analysis of a library‐based hand‐held intervention with rural clinicians
Authors: Wallace Richard L. , Woodward Nakia J. , Clamon Travis S. 
Published: August 2014

AbstractBackgroundThe East Tennessee State University Quillen College of Medicine Library has participated for several years in projects to provide rural clinicians with health information resources.ObjectivesTo determine whether a strategy of hand‐held devices with a best‐evidence point‐of‐care disease tool and a drug database paired with access to a medical library for full‐text articles and training to use the tools would be an affordable way to meet the information needs of rural underserved clinicians.MethodsThis study is a mixed‐methods methodology. The first project was evaluated using a randomised controlled trial (RCT) methodology. The second was evaluated qualitatively using interviews and focus groups.ResultsThe quantitative findings discovered that clinicians equipped with a hand‐held device with evidence‐based software more frequently found answers to clinical questions, found answers more quickly, were more satisfied with information they found and use expensive resources such as continuing medical education, online databases and textbooks less than the group that did not have access to online technology. Qualitative results supported the quantitative findings.ConclusionLibrarians can implement a three‐pronged strategy of the secondary literature via a hand‐held, the primary literature via Loansome Doc and quality training to meet basic information needs of rural clinicians.
What's in a name: putting the skills of librarianship back into circulation
Authors: Brice Anne , Grant Maria J. 
Published: August 2014

AbstractAnne Brice, recipient of the 2014 Cyril Barnard Memorial Prize, reflects on the themes of names and skills of the health library and information professions. She questions whether service users share the same concerns of librarians that this nomenclature is too narrow and too closely associated with the buildings that provide its name. She proposes that in mediation between the users and their required knowledge sits a unique opportunity to place the profession in the centre of knowledge translation.