bluuebunny/crossref_metadata_2025_split huggingface dataset:
Political appointments to rector positions: a shifting landscape in Turkish academia
Authors: Elgin Ceyhun 
Published: July 2024

AbstractThis paper examines the shifting landscape of higher education in Turkey, highlighting a disconcerting trend of politically motivated appointments, coined as “parasailing.” Departing from traditional merit-based norms, this practice of appointing professors without necessary approvals disrupts the academic environment, prompting concerns about the integrity of higher education institutions. The paper introduces the term “parasailing” to elucidate this phenomenon, emphasizing the connection between the appointed professor and their academic destination. In contrast to the widely used term “parachuting,” in Turkish academia the proposed terminology offers a better understanding of the appointment process. The subsequent sections provide an overview of the Turkish academic landscape, explore the origin of the term “parachuting,” review existing literature, define “parasailing,” and connect it to different philosophical thoughts. Overall, this paper contributes to a broader comprehension of the challenges facing Turkish higher education, urging a reconsideration of appointment procedures.
Measuring Bedload Motion Time at Second Resolution Using Benford's Law on Acoustic Data
Authors: Yang Ci‐Jian , Turowski Jens M. , Zhou Qi , Nativ Ron , Tang Hui , Chang Jui‐Ming , Chen Wen‐Sheng 
Published: July 2024

AbstractBedload transport is a natural process that strongly affects the Earth's surface system. An important component of quantifying bedload transport flux and establishing early warning systems is the identification of the onset of bedload motion. Bedload transport can be monitored with high temporal resolution using passive acoustic methods, for example, hydrophones. Yet, an efficient method for identifying the onset of bedload transport from long‐term continuous acoustic data is still lacking. Benford's Law defines a probability distribution of the first‐digit of data sets and has been used to identify anomalies. Here, we apply Benford's law to continuous acoustic recordings from Baiyang hydrometric station, a tributary of Liwu River, Taroko National Park, Taiwan at the frequency of 32 kHz from stationary hydrophones deployed for 3 years since 2019. We construct a workflow to parse sound combinations of bedload transportation and analyze them in the context of hydrometric sensing constraining the onset, and recession of bedload transport. We identified three separate sound classes in the data related to the noise produced by the motion of pebbles, water flow, and air. We identify two bedload transport events that lasted 17 and 45 hr, respectively, covering about 0.35% of the total recorded time. The workflow could be transferred to other different catchments, events, or data sets. Due to the influence of instrument and background noise on the regularity of the residuals of the first‐digit, we recommend identifying the first‐digit distribution of the background noise and ruling it out before implementing this workflow.
Ground Urban Heat Island: Strengthening the Connection Between Spaceborne Thermal Observations and Urban Heat Risk Management
Authors: Hu Leiqiu , Uejio Christopher 
Published: July 2024

AbstractAs urbanization progresses under a changing climate, urban populations face increasing threats from chronically higher heat exposures and more frequent extreme heat events. Understanding the complex urban thermal exposure patterns becomes crucial for effective heat risk management. The spatial advantage of satellite thermal observations positions surface urban heat islands (SUHI) as a primary measure for such applications at the city scale. However, satellite‐inherent biases pose considerable uncertainties. To improve the representation of human‐relevant heat exposure, this study proposes a simple but effective satellite‐based measure– ground urban heat island (GUHI), focusing solely on radiant temperatures from urban ground elements. Leveraging ECOSTRESS land surface temperature product and radiation‐based statistical downscaling, diurnally representative GUHIs were evaluated over NYC. The findings reveal that overall GUHI is consistently warmer than SUHI diurnally. However, GUHI exhibits complex spatial contrasts with SUHI, primarily influenced by vegetation coverage. Various indicators associated with urban structures and materials were examined, showing important but dissimilar roles in shaping the spatial dynamics of GUHI and SUHI. This study highlights the value of satellite thermal observations compared to air temperature while addressing uncertainties in widely adopted practices of using them. By improving the depiction of human‐related urban heat patterns from Earth observations, this research offers valuable insight and more reliable measures to address the urgent requirements for urban heat risk management globally.
Electrical Resistivity Changes During Heating Experiments Unravel Heterogeneous Thermal‐Hydrological‐Mechanical Processes in Salt Formations
Authors: Chen Hang , Wang Jiannan , Luo Linqing , Otto Shawn , Davis Jon , Kuhlman Kristopher L. , Wu Yuxin 
Published: July 2024

AbstractRock salt is considered a suitable medium for the permanent disposal of heat‐generating radioactive waste due to its isolation properties. However, excavation damage and heating induce complex and heterogeneous thermal‐hydrological‐mechanical (THM) processes across different zones. Quantifying this heterogeneity is crucial for accurate long‐term performance assessment models, but traditional methods lack the necessary resolution. This study employs 4D electrical resistivity tomography (ERT) monitoring during controlled heating experiments in a salt formation to unravel the spatiotemporal dynamics of THM processes. Advanced time‐lapse inversion and clustering analysis quantify subsurface properties and map the heterogeneity of THM dynamics. The ERT results can estimate subsurface properties and delineate the damaged and intact zones, enabling appropriate parameterization and representation of processes for long‐term modeling. This approach may be used in further improving the predictive models and ensuring the safe long‐term disposal of radioactive waste in rock salt.
The Response of Ross Sea Shelf Water Properties to Enhanced Amundsen Sea Ice Shelf Melting
Authors: Xie Chuan , Zhang Zhaoru , Chen Yuanjie , Wang Chuning , Zhou Meng 
Published: July 2024

AbstractIce shelves in the Amundsen Sea have experienced the most rapid melting in the Antarctic and are expected to accelerate throughout this century under climate warming. In this study, a high‐resolution ocean‐sea ice‐ice shelf model is employed to conduct sensitivity experiments to explore the effects of increasing melt rates of the Amundsen Sea ice shelves on hydrography, sea ice and ice shelf in the Ross Sea. The results indicate that the substantial inflow of meltwater significantly freshens the Ross Sea, inhibiting the formation and export of the Dense Shelf Water, the volume of which is reduced by 19%–33% on the shelf. Temperatures in the eastern and western Ross Sea exhibit different responses to the enhanced meltwater input. The freshening of the western Ross Sea weakens the mesoscale eddy activities which are efficient in carrying warm Circumpolar Deep Water onto the shelf, leading to an average temperature decrease of 0.02–0.08°C. Conversely, in the eastern Ross Sea, there is a marked warming outside the shelf under increased meltwater, which results from zonal pressure gradients associated with the meltwater distributions. This consequently causes stronger on‐shelf heat transport and shows warming of 0.12–0.22°C on the eastern Ross Sea shelf. The narrow shelf in the eastern Ross Sea allows the warmer water to reach the Ross Ice Shelf (RIS) front, resulting in an about 6%–9% increase in the RIS melting. These results suggest a possible mechanism for acceleration in the RIS melting in the future that is associated with enhanced meltwater inflow.
Mutation in Bruton Tyrosine Kinase (BTK) A428D confers resistance To BTK-degrader therapy in chronic lymphocytic leukemia
Authors: Wong Richard L. , Choi Michael Y. , Wang Huan-You , Kipps Thomas J. 
Published: July 2024

AbstractTargeting BTK has profoundly changed the face of CLL treatment over the past decade. Iterative advances in the cat and mouse game of resistance and redesign have moved BTK inhibitors from covalent to non-covalent and now targeted protein degraders. However, contrary to the presumption that protein degraders may be impervious to mutations in BTK, we now present clinical evidence that a mutation in the kinase domain of BTK, namely A428D, can confer disease resistance to a BTK degrader currently in clinical trials, that is BGB-16673. Modeling of a BTK A428D mutation places a negatively charged aspartic acid in place of the hydrophobic side chain of alanine within the binding pocket of another BTK-degrader in clinical development, namely NX-2127, suggesting that CLL cells with BTK A428D also may be resistant to NX-2127, as they already are known to be with either non-covalent or covalent inhibitors of BTK. Consequently, the two BTK degraders furthest advanced in clinical trials potentially may select for CLL cells with BTK A428D that are resistant to all approved BTKi’s.
An exploratory study of the damage markers NfL, GFAP, and t-Tau, in cerebrospinal fluid and other findings from a patient cohort enriched for suspected autoimmune psychiatric disease
Authors: Syk Mikaela , Tornvind Emma , Gallwitz Maike , Fällmar David , Amandusson Åsa , Rothkegel Holger , Danfors Torsten , Thulin Måns , Rasmusson Annica J. , Cervenka Simon , Pollak Thomas A. , Endres Dominique , van Elst Ludger Tebartz , Bodén Robert , Nilsson Björn M. , Nordmark Gunnel , Burman Joachim , Cunningham Janet L. 
Published: July 2024

AbstractThere is growing evidence suggesting that immunological mechanisms play a significant role in the development of psychiatric symptoms in certain patient subgroups. However, the relationship between clinical red flags for suspected autoimmune psychiatric disease and signs of central nervous system (CNS) pathology (e.g., routine cerebrospinal fluid (CSF) alterations, CNS damage markers, neurophysiological or neuroimaging findings) has received limited attention. Here, we aimed to describe the prevalence and distribution of potential CNS pathologies in psychiatric patients in relation to clinical red flags for autoimmune psychiatric disease and psychiatric symptoms. CSF routine findings and CNS damage markers; neurofilament light chain protein (NfL), glial fibrillary acidic protein (GFAP) and total Tau (t-Tau), in CSF from 127 patients with psychiatric disease preselected for suspected immunological involvement were related to recently proposed clinical red flags, psychiatric features, and MRI and EEG findings. Twenty-one percent had abnormal routine CSF findings and 27% had elevated levels of CNS damage markers. Six percent had anti-neuronal antibodies in serum and 2% had these antibodies in the CSF. Sixty-six percent of patients examined with MRI (n = 88) had alterations, mostly atrophy or nonspecific white matter lesions. Twenty-seven percent of patients with EEG recordings (n = 70) had abnormal findings. Elevated NfL levels were associated with comorbid autoimmunity and affective dysregulation symptoms. Elevated t-Tau was associated with catatonia and higher ratings of agitation/hyperactivity. Elevated GFAP was associated with acute onset, atypical presentation, infectious prodrome, tics, depressive/anxiety symptom ratings and overall greater psychiatric symptom burden. In conclusion, preselection based on suspected autoimmune psychiatric disease identifies a population with a high prevalence of CSF alterations suggesting CNS pathology. Future studies should examine the value of these markers in predicting treatment responses.
Air pollution impacts from warehousing in the United States uncovered with satellite data
Authors: Kerr Gaige Hunter , Meyer Michelle , Goldberg Daniel L. , Miller Joshua , Anenberg Susan C. 
Published: July 2024

AbstractRegulators, environmental advocates, and community groups in the United States (U.S.) are concerned about air pollution associated with the proliferating e-commerce and warehousing industries. Nationwide datasets of warehouse locations, traffic, and satellite observations of the traffic-related pollutant nitrogen dioxide (NO2) provide a unique capability to evaluate the air quality and environmental equity impacts of these geographically-dispersed emission sources. Here, we show that the nearly 150,000 warehouses in the U.S. worsen local traffic-related air pollution with an average near-warehouse NO2 enhancement of nearly 20% and are disproportionately located in marginalized and minoritized communities. Near-warehouse truck traffic and NO2 significantly increase as warehouse density and the number of warehouse loading docks and parking spaces increase. Increased satellite-observed NO2 near warehouses underscores the need for indirect source rules, incentives for replacing old trucks, and corporate commitments towards electrification. Future ground-based monitoring campaigns may help track impacts of individual or small clusters of facilities.
Reconstruction of zinc-metal battery solvation structures operating from −50 ~ +100 °C
Authors: Yao Lingbo , Liu Jiahe , Zhang Feifan , Wen Bo , Chi Xiaowei , Liu Yu 
Published: July 2024

AbstractSerious solvation effect of zinc ions has been considered as the cause of the severe side reactions (hydrogen evolution, passivation, dendrites, and etc.) of aqueous zinc metal batteries. Even though the regulation of cationic solvation structure has been widely studied, effects of the anionic solvation structures on the zinc metal were rarely examined. Herein, co-reconstruction of anionic and cationic solvation structures was realized through constructing a new multi-component electrolyte (Zn(BF4)2-glycerol-boric acid-chitosan-polyacrylamide, simplified as ZGBCP), which incorporates double crosslinking network via the esterification, protonation and polymerization reactions, thereby combining multiple advantages of ‘liquid-like’ high conductivity, ‘gel-like’ robust interface, and ‘solid-like’ high Zn2+ transfer number. Based on the ZGBCP electrolyte, the Zn anodes achieve record-low polarization and stable cycling. Furthermore, the ZGBCP electrolyte renders the AZMBs ultrawide working temperature (−50 °C ~ +100 °C) and ultralong cycle life (30000 cycles), which further validates the feasibility of the dual solvation structure strategy and provides a innovative perspective for the development of high-performance AZMBs.
Uncovering the phonon spectra and lattice dynamics of plastically deformable InSe van der Waals crystals
Authors: Wu Jiangtao , Lin Yifei , Shu Mingfang , Liu Yifei , Ma Yupeng , Lin Gaoting , Zhang Cuiping , Jiao Pengfei , Zhu Fengfeng , Wu Yan , Ewings Russell A. , Walker Helen C. , Deng Guochu , Chi Songxue , Jiang Shengwei , Baggioli Matteo , Jin Min , Wang Haozhe , Xie Weiwei , Wei Tian-Ran , Yang Jiong , Shi Xun , Ma Jie 
Published: July 2024

AbstractStacking two-dimensional (2D) van der Waals (vdW) materials in a layered bulk structure provides an appealing platform for the emergence of exotic physical properties. As a vdW crystal with exceptional plasticity, InSe offers the opportunity to explore various effects arising from the coupling of its peculiar mechanical behaviors and other physical properties. Here, we employ neutron scattering techniques to investigate the correlations of plastic interlayer slip, lattice anharmonicity, and thermal transport in InSe crystals. Not only are the interlayer slip direction and magnitude well captured by shifts in the Bragg reflections, but we also observe a deviation from the expected Debye behaviour in the heat capacity and lattice thermal conductivity. Combining the experimental data with first-principles calculations, we tentatively attribute the observed evidence of strong phonon-phonon interactions to a combination of a large acoustic-optical frequency resonance and a nesting effect. These findings correlate the macroscopic plastic slip and the microscopic lattice dynamics, providing insights into the mechano-thermo coupling and modulation in 2D vdW materials.
Many-body enhancement of high-harmonic generation in monolayer MoS2
Authors: Chang Lee Victor , Yue Lun , Gaarde Mette B. , Chan Yang-hao , Qiu Diana Y. 
Published: July 2024

AbstractMany-body effects play an important role in enhancing and modifying optical absorption and other excited-state properties of solids in the perturbative regime, but their role in high harmonic generation (HHG) and other nonlinear response beyond the perturbative regime is not well-understood. We develop here an ab initio many-body method to study nonperturbative HHG based on the real-time propagation of the non-equilibrium Green’s function with the GW self energy. We calculate the HHG of monolayer MoS2 and obtain good agreement with experiment, including the reproduction of characteristic patterns of monotonic and nonmonotonic harmonic yield in the parallel and perpendicular responses, respectively. Here, we show that many-body effects are especially important to accurately reproduce the spectral features in the perpendicular response, which reflect a complex interplay of electron-hole interactions (or exciton effects) in tandem with the many-body renormalization and Berry curvature of the independent quasiparticle bandstructure.
Multiomic profiling of medulloblastoma reveals subtype-specific targetable alterations at the proteome and N-glycan level
Authors: Godbole Shweta , Voß Hannah , Gocke Antonia , Schlumbohm Simon , Schumann Yannis , Peng Bojia , Mynarek Martin , Rutkowski Stefan , Dottermusch Matthias , Dorostkar Mario M. , Korshunov Andrey , Mair Thomas , Pfister Stefan M. , Kwiatkowski Marcel , Hotze Madlen , Neumann Philipp , Hartmann Christian , Weis Joachim , Liesche-Starnecker Friederike , Guan Yudong , Moritz Manuela , Siebels Bente , Struve Nina , Schlüter Hartmut , Schüller Ulrich , Krisp Christoph , Neumann Julia E. 
Published: July 2024

AbstractMedulloblastomas (MBs) are malignant pediatric brain tumors that are molecularly and clinically heterogenous. The application of omics technologies—mainly studying nucleic acids—has significantly improved MB classification and stratification, but treatment options are still unsatisfactory. The proteome and their N-glycans hold the potential to discover clinically relevant phenotypes and targetable pathways. We compile a harmonized proteome dataset of 167 MBs and integrate findings with DNA methylome, transcriptome and N-glycome data. We show six proteome MB subtypes, that can be assigned to two main molecular programs: transcription/translation (pSHHt, pWNT and pG3myc), and synapses/immunological processes (pSHHs, pG3 and pG4). Multiomic analysis reveals different conservation levels of proteome features across MB subtypes at the DNA methylome level. Aggressive pGroup3myc MBs and favorable pWNT MBs are most similar in cluster hierarchies concerning overall proteome patterns but show different protein abundances of the vincristine resistance-associated multiprotein complex TriC/CCT and of N-glycan turnover-associated factors. The N-glycome reflects proteome subtypes and complex-bisecting N-glycans characterize pGroup3myc tumors. Our results shed light on targetable alterations in MB and set a foundation for potential immunotherapies targeting glycan structures.
Future changes in coastal upwelling and biological production in eastern boundary upwelling systems
Authors: Du Tianshi , Wang Shengpeng , Jing Zhao , Wu Lixin , Zhang Chao , Zhang Bihan 
Published: July 2024

AbstractUpwelling along oceanic eastern boundaries has attracted significant attention due to its profound effects on ocean productivity and associated biological and socioeconomic implications. However, uncertainty persists regarding the evolution of coastal upwelling with climate change, particularly its impact on future biological production. Here, using a series of state-of-the-art climate models, we identify a significant seasonal advancement and prolonged duration of upwelling in major upwelling systems. Nevertheless, the upwelling intensity (total volume of upwelled water) exhibits complex changes in the future. In the North Pacific, the upwelling is expected to attenuate, albeit with a minor magnitude. Conversely, in other basins, coastal upwelling diminishes significantly in equatorward regions but displays a slight decline or even an enhancement at higher latitudes. The climate simulations also reveal a robust connection between changes in upwelling intensity and net primary production, highlighting the crucial impact of future coastal upwelling alterations on marine ecosystems.
Tunable even- and odd-denominator fractional quantum Hall states in trilayer graphene
Authors: Chen Yiwei , Huang Yan , Li Qingxin , Tong Bingbing , Kuang Guangli , Xi Chuanying , Watanabe Kenji , Taniguchi Takashi , Liu Guangtong , Zhu Zheng , Lu Li , Zhang Fu-Chun , Wu Ying-Hai , Wang Lei 
Published: July 2024

AbstractFractional quantum Hall (FQH) states are exotic quantum many-body phases whose elementary charged excitations are anyons obeying fractional braiding statistics. While most FQH states are believed to have Abelian anyons, the Moore–Read type states with even denominators – appearing at half filling of a Landau level (LL) – are predicted to possess non-Abelian excitations with appealing potential in topological quantum computation. These states, however, depend sensitively on the orbital contents of the single-particle LL wavefunctions and the LL mixing. Here we report magnetotransport measurements on Bernal-stacked trilayer graphene, whose multiband structure facilitates interlaced LL mixing, which can be controlled by external magnetic and displacement fields. We observe robust FQH states including even-denominator ones at filling factors ν = − 9/2, − 3/2, 3/2 and 9/2. In addition, we fine-tune the LL mixing and crossings to drive quantum phase transitions of these half-filling states and neighbouring odd-denominator ones, exhibiting related emerging and waning behaviour.
Innovative molecular networking analysis of steroids and characterisation of the urinary steroidome
Authors: Chen Ting , Massias Justine , Bertrand Samuel , Guitton Yann , Le Bizec Bruno , Dervilly Gaud 
Published: July 2024

AbstractSteroids are cholesterol-derived biomolecules that play an essential role in biological processes. These substances used as growth promoters in animals are strictly regulated worldwide. Targeted assays are the conventional methods of monitoring steroid abuse, with limitations: only detect known metabolites. Metabolism leads to many potential compounds (isomers), which complicates the analysis. Thus, to overcome these limitations, non-targeted analysis offers new opportunities for a deeper understanding of metabolites related to steroid metabolism. Molecular networking (MN) appears to be an innovative strategy combining high-resolution mass spectrometry and specific data processing to study metabolic pathways. In the present study, two databases and networks of steroids were constructed to lay the foundations for the implementation of the GNPS-MN approach. Steroids of the same family were grouped together, nandrolone and testosterone were linked to other analogues. This network and associated database were then applied to a few urine samples in order to demonstrate the annotation capacity in steroidome study. The results show that MN strategy could be used to study steroid metabolism and highlight biomarkers.