bluuebunny/crossref_metadata_2025_split huggingface dataset:
Does an Individual's Fitness Level Affect Baseline Concussion Symptoms?
Authors: Mrazik Martin , Naidu Dhiren , Lebrun Constance , Game Alex , Matthews-White Joan 
Published: April 2013

Context:
Variables that may influence baseline concussion symptoms should be investigated.

Objective:
To evaluate the effect of physical fitness on self-report of baseline concussion symptoms in collegiate athletes and students.

Design:
Controlled laboratory study.

Patients or Other Participants:
A total of 125 undergraduates, including 95 collegiate athletes and 30 recreational athletes (83 males, 42 females).

Intervention(s):
Participants completed the Standardized Concussion Assessment Tool 2 (SCAT2; symptom report) at baseline, within 10 minutes of completing the Leger test, and within 24 hours of the initial baseline test. The Leger (beep) test is a shuttle-run field test used to predict maximal aerobic power.

Main Outcome Measure(s):
The total symptom score on the SCAT2 was calculated and analyzed with a repeated-measures analysis of variance. A linear regression analysis was used to determine if 3 variables (sport type, sex, or fitness level) accounted for a significant amount of the variance in the baseline symptom report.

Results:
Participants reported more symptoms postactivity but fewer symptoms at 24 hours compared with baseline, representing a time effect in our model (F2,234 = 47.738, P &lt; .001). No interactions were seen among the independent variables. We also found an effect for fitness level, with fitter individuals reporting fewer symptoms at all 3 time intervals. The regression analysis revealed that fitness level accounted for a significant amount of the variance in SCAT2 symptoms at baseline (R 2 = 0.22, F3,121 = 11.44, P &lt; .01).

Conclusions:
Fitness level affected the baseline concussion symptom report. Exercise seems to induce concussion symptom reporting, and symptom severity may be a function of an athlete's level of conditioning. Sports medicine professionals should consider an athlete's level of fitness when conducting baseline concussion symptom assessments.
La sociologie du genre : une contribution originale à la compréhension du suicide chez les hommes
Authors: Roy Philippe 
Published: April 2013

Il y a un consensus à l’effet que le suicide soit un problème social. Mais quelle est la contribution de la sociologie à la recherche sur le suicide ? Cet article présente un bref survol des bases historiques de la sociologie du suicide et de son évolution à travers l’étude de la déviance et de l’exclusion. Sur le plan de l’application, la sociologie du genre a notamment contribué à mieux comprendre comment certains aspects de la socialisation masculine, comme le rapport rigide aux normes masculines, agissent comme des facteurs de risque suicidaire ou comme des pistes de rétablissement.
Risque suicidaire et préférences musicales : y a-t-il un lien ?
Authors: Mikolajczak Gladys , Desseilles Martin 
Published: April 2013

La musique occupe une fonction importante dans la vie des adolescents. Dans cette revue, nous répondrons à deux questions sur les liens entre la musique et le suicide. La première sera de savoir si certaines musiques peuvent favoriser le processus suicidaire (idéations et passage à l’acte) et la deuxième examinera si la musique peut constituer un outil pour diminuer le risque suicidaire. Plusieurs facteurs potentiellement impliqués dans le lien entre les préférences musicales et le processus suicidaire seront développés : l’effet Velten et la procédure musicale d’induction de l’humeur, l’identification et l’apprentissage par imitation, l’influence des médias ainsi que les caractéristiques individuelles. Une approche multifactorielle est nécessaire pour comprendre les liens complexes et bidirectionnels qui unissent les préférences musicales au risque suicidaire.
‘You Can Touch But Do Not Read’: The ‘Future‐Rustic’ Work of Kathryn Findlay
Authors: Titman Mark 
Published: April 2013

Abstract‘By turns curvaceous, fluffy, leafy, green, soft and hairy’, the work of Kathryn Findlay is palpably ‘future‐rustic’ in all its formal and material manifestations. Guest‐editor Mark Titman explains how Findlay's designs also more subtly respond ‘to the richness of a given situation, the resources and natural conditions that each site and its surrounding context reveals’, coming out of an approach that has been equally influenced by her rural childhood on a farm in Scotland as almost two decades of working in Japan.
Wild City: MVRDV ‐ Weaving Nature and the Urban
Authors: Pozo Gil Marta 
Published: April 2013

AbstractArchitect Marta Pozo Gil, who leads the Sustainability Department at MVRDV, draws on a correlation between people's retreat indoors, with urban populations becoming increasingly divorced from nature, and the growing ambitions for ‘green’ cities and the ensuing benefits they bring to our quality of life. How might it, though, be possible to realise such a vision? Pozo Gil describes some of MVRDV's lesser‐known projects that weave nature into the city.
Brave New Now
Authors: Young Liam 
Published: April 2013

AbstractUnder Tomorrow's Sky is a fictional future city. For the project, speculative architect Liam Young assembled a think‐tank of scientists, technologists, futurists, illustrators and science‐fiction authors to collectively develop this imaginary place, the landscapes that surround it and the stories it contains. The city forms a stage set for a collection of fictions, emerging infrastructures and design experiments. It is an imaginary landscape extrapolated from the wonders and possibilities of emerging biological and technological research. Here, speculative fiction provides a critical tool, which is visionary in its trajectory while provoking us to examine some of the most pertinent questions facing us today.
Bacterial Cellulose Nanofibrillar Patch as a Wound Healing Platform of Tympanic Membrane Perforation
Authors: Kim Jangho , Kim Seung Won , Park Subeom , Lim Ki Taek , Seonwoo Hoon , Kim Yeonju , Hong Byung Hee , Choung Yun‐Hoon , Chung Jong Hoon 
Published: April 2013

AbstractBacterial cellulose (BC)‐based biomaterials on medical device platforms have gained significant interest for tissue‐engineered scaffolds or engraftment materials in regenerative medicine. In particular, BC has an ultrafine and highly pure nanofibril network structure and can be used as an efficient wound‐healing platform since cell migration into a wound site is strongly meditated by the structural properties of the extracellular matrix. Here, the fabrication of a nanofibrillar patch by using BC and its application as a new wound‐healing platform for traumatic tympanic membrane (TM) perforation is reported. TM perforation is a very common clinical problem worldwide and presents as conductive hearing loss and chronic perforations. The BC nanofibrillar patch can be synthesized from Gluconacetobacter xylinus; it is found that the patch contained a network of nanofibrils and is transparent. The thickness of the BC nanofibrillar patch is found to be approximately 10.33 ± 0.58 μm, and the tensile strength and Young's modulus of the BC nanofibrillar patch are 11.85 ± 2.43 and 11.90 ± 0.48 MPa, respectively, satisfying the requirements of an ideal wound‐healing platform for TM regeneration. In vitro studies involving TM cells show that TM cell proliferation and migration are stimulated under the guidance of the BC nanofibrillar patch. In vivo animal studies demonstrate that the BC nanofibrillar patch promotes the rate of TM healing as well as aids in the recovery of TM function. These data demonstrate that the BC nanofibrillar patch is a useful wound‐healing platform for TM perforation.
Nutrients intake as determinants of blood lead and cadmium levels in Colombian pregnant women
Authors: Suarez‐Ortegón Milton F. , Mosquera Mildrey , Caicedo Diana M. , De Plata Cecilia Aguilar , Méndez Fabian 
Published: April 2013

ObjectiveTo evaluate the relationship between nutrients intake in the first trimester of pregnancy and blood levels of lead and cadmium during the first and third trimesters of gestation.MethodsA total of 381 pregnant women were enrolled. Blood lead and cadmium were measured using electrothermal atomic absorption spectrometry, and dietary intake was assessed using 24‐h recall questionnaire.ResultsLead levels in the first trimester were negatively correlated with cadmium levels in the two trimesters, and levels of both metals correlated positively in the third trimester. Zinc and calcium intakes were negatively associated with blood lead during third trimester. Thiamine and folic acid intakes were negatively and positively associated (respectively) with blood lead at third trimester with marginal significance. Fat, niacin, and vitamin B12 intakes were significantly and positively associated with blood cadmium at first trimester. Folic acid and zinc intakes showed positive and marginally significant associations with blood cadmium without adjustments. At third trimester, blood cadmium was negatively associated to ascorbic acid intake, and positively associated with iron intake with a marginal significance.ConclusionsPossible acute and late effects of nutrients intake in blood lead and cadmium levels could be related with associations exclusively observed in the first and third trimester. This study represents the first exploration of relationships among a wide range of nutrients intake in the first trimester of pregnancy with blood lead and cadmium in first and third trimester of gestation. Further studies are required to confirm the findings mentioned herein. Am. J. Hum. Biol. 25:344–350, 2013. © 2013 Wiley Periodicals, Inc.
The associations of SES, obesity, sport activity, and perceived neighborhood environments: Is there a model of environmental injustice penalizing portuguese children?
Authors: Nogueira Helena , Gama Augusta , Mourão Isabel , Marques Vitor , Ferrão Maria , Padez Cristina 
Published: April 2013

ObjectivesThis study analyses the associations between children's obesity, sports activity (SA), and perceived environmental characteristics with the children's SES.MethodsA sample of 1,885 Portuguese children, aged 3–10 years, living in Coimbra, Portugal, was observed. Weight and height were measured and obesity was defined by age‐and sex‐specific, BMI cut‐off points. Questionnaires included variables on SA levels, SES and parental neighborhood perceptions were done. A CATPCA was performed and two neighborhood dimensions were achieved. The independent associations of SES with obesity, SA and perceived neighborhood dimensions was analyzed using ordered logistic regressions.ResultsChildren of low [odds ratio (OR) = 1.76; confidence interval (CI) = 1.25–1.99] and medium SES (OR = 1.57; CI = 1.34–2.33) were more likely to be obese than their high‐SES peers, less likely to participate in SA (low SES OR = 0.177; CI = 0.12–0.26; medium SES OR = 0.357; CI = 0.24–0.53), and their parents were less likely to have positive perceptions of their built environment (low SES OR = 0.516; CI = 0.38–0.70; medium SES OR = 0.565; CI = 0.37–0.86).ConclusionsObesity increases and SA decreases among children with the lowest SES and these living in neighborhoods with higher perceived risk. This finding suggests a model of environmental injustice, whereby differential access to the neighborhood's resources overlaps with familial socioeconomic disadvantage. Am. J. Hum. Biol. 25:434–436, 2013. © 2013 Wiley Periodicals, Inc.
A direct fluorescence‐based technique for cellular localization of amylin
Authors: Pillay Karen , Govender Patrick 
Published: April 2013

AbstractAmylin has been implicated in type II diabetes because of its inherent property to misfold into toxic aggregates. Although it has been shown that amylin interacts with cell membranes, no study to date has monitored the association process using a direct approach. The present study uses confocal microscopy to identify the localization of carboxyfluorescein‐labeled amylin in RIN‐5F cells. In addition, the size of the aggregates that are formed was evaluated using nanoparticle tracking analysis. In support of previous findings, amylin was observed to interact with and remain associated with the cell membrane. The cell membrane‐associated aggregates spanned a size range of 130–800 nm.
Improved efficacy of fluconazole against candidiasis using bio‐based microemulsion technique
Authors: Nirmala M. Joyce , Mukherjee Amitava , Chandrasekaran N. 
Published: April 2013

AbstractCandida albicans is a common fungal pathogen that causes systemic and superficial infections in most immunocompromised patients. Fluconazole, a synthetic triazole antifungal agent, is the most prescribed drug used in treating this pathogen. But because of its poor solubilization in water and the emergence of resistant strains against this antimycotic drug, we aimed at devising a unique microemulsion drug delivery system for fluconazole against candidiasis. A clear oil‐in‐water microemulsion system, consisting of clove oil as oil phase, Tween 20 as surfactant, and water as aqueous phase was developed using a ternary phase diagram. Physicochemical characterization was done to understand the internal physicochemical state. The bulk drug, fluconazole, that measured several microns in length was reduced to a 10–65 nm range with no means of high‐energy methods as confirmed by transmission electron microscopy. The very small and uniform spherical structure of the drug‐loaded microemulsion system could be of high impact to the biological system as the efficacy of fluconazole is greatly improved when compared with its conventional bulk form. The optimized microemulsion exhibited significantly higher antifungal activity at a minimum concentration (8 µg/ml) of fluconazole as examined by fluorescence and scanning electron microscopy. Thus, our report discloses an excellent oral drug delivery system.
Die Sanierung des Schlosses Steinort in Masuren
Authors: Himburg Stefan 
Published: April 2013

AbstractDas Steinorter Schloss in Masuren ist der ehemalige Stammsitz der Familie Lehndorff. Neben der großen geschichtlichen Bedeutung ist Schloss Steinort als einzige nahezu komplett erhaltene Gesamtanlage der ehemaligen ostpreußischen Familiengüter auch bauhistorisch überaus interessant. Es ist das Hauptprojekt der in Görlitz ansässigen Deutsch‐Polnischen Stiftung Kulturpflege und Denkmalschutz (DPS) und deren polnischer Schwesterstiftung Polsko‐Niemiecka Fundacja (PNF) in Warschau. Die Sanierung soll auch unter Einbeziehung von Hochschulen erfolgen. Der nachfolgende Beitrag stellt das Projekt vor und gibt den aktuellen Stand der Sanierungsplanung wieder.
Urinary d‐lactate levels reflect renal function in aristolochic acid‐induced nephropathy in mice
Authors: Huang Tzu‐Chuan , Chen Shih‐Ming , Li Yi‐Chieh , Lee Jen‐Ai 
Published: April 2013

ABSTRACTUrinary d‐lactate is highly correlated to diabetic nephropathy – a progressive kidney disease in renal glomeruli. In this study, we used a C3H/3e mouse model to investigate the relationship between urinary d‐lactate and aristolochic acid nephropathy where the glomerular structure is not affected. The nephropathy was induced using intravenous injections of aristolochic acid at a dosage of 10 mg/kg per day for 5 days and was characterized biochemically and histologically. The urinary excretions of proteins, N‐acetyl‐β‐d‐glucosaminidase and serum creatinine were determined and connected to histological conventional findings. Urinary d‐lactate was analyzed using column‐switching high‐performance liquid chromatography with fluorescence detection. The results showed a remarkable increase of urinary markers, including of urinary proteins and N‐acetyl‐β‐d‐glucosaminidase, and the histological examination confirmed a diagnosis of acute tubule necrosis. The ratio of d‐lactate to creatinine in the urine of aristolochic acid‐treated mice was approximately 36 times greater than that of the mice in the control group (p < 0.05). The ratios for the two groups of mice were 311.00 ± 71.70 and 8.60 ± 1.80 µmol/mmol creatinine, respectively. These data confirm in vivo that urinary d‐lactate reflects renal injury conditions in aristolochic acid‐treated mice and may be a marker for the assessment of nephropathy. Copyright © 2013 John Wiley & Sons, Ltd.
Catalyst Development for CO2 Hydrogenation to Fuels
Authors: Rodemerck Uwe , Holeňa Martin , Wagner Edmund , Smejkal Quido , Barkschat Axel , Baerns Manfred 
Published: April 2013

AbstractNew active and selective catalyst compositions for the hydrogenation of CO2 to mainly fuel‐type higher hydrocarbons were developed by application of an evolutionary strategy. It was shown that Fe and K supported on TiO2 and modified by Cu plus other modifiers resulted in highest selectivity for C5–C15 hydrocarbons at high degrees of CO2 conversion. Co containing catalysts were less suited since they produced methane and light hydrocarbons with high selectivities. A detailed study of reaction conditions showed that selected catalyst compositions were able to reach high CO2 conversion with still low selectivities to methane at higher reaction temperatures and a higher H2/CO2 ratio.
TIPS‐TTF as a Precursor of Low‐Symmetry TTF Derivatives: Steric Protection Strategy in the Regioselective CH Modification of TTF
Authors: Ueno Ryota , Fujino Daishi , Yorimitsu Hideki , Osuka Atsuhiro 
Published: April 2013

AbstractTriisopropylsilyltetrathiafulvalene (TIPS‐TTF) has been devised as a promising platform for the synthesis of low‐symmetry TTF derivatives. The bulky TIPS group allows TIPS‐TTF to undergo palladium‐catalyzed direct diarylation as well as LDA‐mediated dilithiation exclusively on the roomier dithiole ring. Subsequent fluoride‐mediated protodesilylation provided vicinally difunctionalized TTF, which could undergo further functionalization.
ChemInform Abstract: Stabilization of Decatellurium Molecules in Isolated and Concatenated Clusters.
Authors: Guenther Anja , Isaeva Anna , Ruck Michael 
Published: April 2013

AbstractThe molecular cluster compounds (Te10)[Rh(TeCl4)(TeCl3)]2 (I), (Te10)[Ir(TeBr4)(TeBr3)]2 (II), (Te10)[Ru(TeI4)(TeI2)]2 (III), (Te10) [Rh(TeI4)(TeI2)] 2(TeI4)(Te2I2) (IV), (Te10) [Ir(TeI4)(TeI2)] 2(TeI4)(Te2I2) (V) and the one‐dimensional cluster polymer (Te10I2) [Ir(TeI4)]2(Te4)I2 (VI) are obtained by cooling melts of the respective transition metals, Te, and TeX4 (X: Cl, Br, I) in stoichiometric ratios or M:Te:I = 2:14:12 (IV, V) (fused silica tubes, 523—573 K, 7 d).
ChemInform Abstract: Synthesis, Characterization and Electrochemical Performance of Li2FeSiO4/C for Lithium‐Ion Batteries.
Authors: Chen Weihua , Lan Meng , Zhu Dan , Wang Cuilian , Xue Shangru , Yang Changchun , Li Zexian , Zhang Jianmin , Mi Liwei 
Published: April 2013

AbstractLi2FeSiO4/C is synthesized by solid state reaction of Li2SiO3 (obtained by ball milling of LiOH·H2O and H2SiO3), FeC2O4, citric acid, and sucrose (923 K, 7 h).
ChemInform Abstract: Highly Regio‐, Diastereo‐, and Enantioselective 1,6‐ and 1,8‐Additions of Azlactones to Di‐ and Trienyl N‐Acylpyrroles.
Authors: Uraguchi Daisuke , Yoshioka Ken , Ueki Yusuke , Ooi Takashi 
Published: April 2013

AbstractThis conjugate addition reaction proceeds with good diastereoselectivity (20:1, unless otherwise mentioned), good 1,6‐ or 1,8‐regioselectivity (for dienyl resp.
ChemInform Abstract: Cooperative Catalysis by Iridium Complexes with a Bipyridonate Ligand: Versatile Dehydrogenative Oxidation of Alcohols and Reversible Dehydrogenation—Hydrogenation Between 2‐Propanol and Acetone.
Authors: Kawahara Ryoko , Fujita Ken‐ichi , Yamaguchi Ryohei 
Published: April 2013

AbstractThis dehydrogenation works with catalyst loadings as low as 0.002 mol% (turnover numbers up to 47,500).
ChemInform Abstract: Ruthenium‐Catalyzed Highly Regio‐ and Stereoselective Hydroarylation of Aryl Carbamates with Alkynes via C—H Bond Activation.
Authors: Reddy Mallu Chenna , Jeganmohan Masilamani 
Published: April 2013

AbstractChelation‐assisted alkenylation of the ortho‐C—H bond of aryl carbamates with alkynes gives highly substituted alkene derivatives such as (III), (V), and (VIII) in a highly regio‐ and stereoselective manner.
ChemInform Abstract: Improved Protocol for the Synthesis of Flexibly Protected Morpholino Monomers from Unprotected Ribonucleosides.
Authors: Pattanayak Sankha , Paul Sibasish , Nandi Bappaditya , Sinha Surajit 
Published: April 2013

AbstractThe synthesis of protected morpholine monomers such as (VII) and (IX) from unprotected ribonucleosides (I) is achieved by using oxidative glycol cleavage and reductive amination.
ChemInform Abstract: Synthesis of β‐Hydroxy O‐Alkyl Hydroxylamines from Epoxides Using a Convenient and Versatile Two‐Step Procedure.
Authors: Malik Gaelle , Ferry Angelique , Guinchard Xavier , Crich David 
Published: April 2013

AbstractBase‐mediated regioselective ring opening of epoxides with acetophenone oxime (II) followed by oxidative cleavage of the resulting oxime with DNH produces medicinally interesting hydroxylamine units which are isolated as N‐protected derivatives.
ChemInform Abstract: Unexpected Extension of Usage of PPh3/CBr4, a Versatile Reagent: Isomerization of Aromatic Allylic Alcohols.
Authors: Gong Wanchun , Liu Yun , Xue Jijun , Xie Zhixiang , Li Ying 
Published: April 2013

AbstractThe catalyzed isomerization reaction of aromatic allylic alcohols with electron‐donating groups at the phenyl ring affords the corresponding ketones or aldehydes but fails in case of substrates containing electron‐withdrawing groups.
ChemInform Abstract: Ligand‐Enabled Methylene C(sp3)—H Bond Activation with a Pd(II) Catalyst.
Authors: Wasa Masayuki , Chan Kelvin S. L. , Zhang Xing‐Guo , He Jian , Miura Masanori , Yu Jin‐Quan 
Published: April 2013

AbstractBest results are obtained using 2‐isobutoxyquinoline as the ligand (no stereochemical assignments for most compounds).
ChemInform Abstract: Synthesis of Hydroxamic Acids by Using the Acid Labile O‐2‐Methylprenyl Protecting Group.
Authors: Nikitjuka Anna , Jirgensons Aigars 
Published: April 2013

AbstractVarious carboxylic acids can be converted into the corresponding hydroxamic acid via coupling with hydroxylamine (I) under conditions A) or C) and subsequent deprotection with TFA.
ChemInform Abstract: Pd(OAc)2 Without Added Ligand as an Active Catalyst for Mizoroki—Heck Reaction in Aqueous Media.
Authors: Amini Mojtaba , Bagherzadeh Mojtaba , Moradi‐Shoeili Zeinab , Boghaei Davar M. 
Published: April 2013

AbstractThe present new method provides internal E‐isomers exclusively, except the reaction with acrylonitrile (IV) gives a mixture of stereoisomers.
ChemInform Abstract: Preparation of New Nitrogen‐Bridged Heterocycles. Part 76. Reactions of 3‐[Bis(methylthio)methylene]‐2(3H)‐imidazo[1,2‐a]pyridinones with Quinolinium and Isoquinolinium N‐Unsubstituted Aminides.
Authors: Kakehi Akikazu , Abe Takashi , Suga Hiroyuki , Itoh Kennosuke 
Published: April 2013

Abstract1,3‐Dipolar cycloaddition reactions of (I) with (II) or (IV) followed by elimination of methanethiol afford spirocompounds (III) or (V), respectively.
ChemInform Abstract: Protonation‐Assisted Conjugate Addition of Axially Chiral Enolates: Asymmetric Synthesis of Multisubstituted β‐Lactams from α‐Amino Acids.
Authors: Kawabata Takeo , et al. et al. 
Published: April 2013

Abstractβ‐Lactams are prepared in a highly enantioselective manner from α‐amino acids via intermediary formed axially chiral enolates.
ChemInform Abstract: Diastereoselective Synthesis of Enantiopure γ‐Butenolide‐butyrolactones Towards Pseudopterogorgia Lactone Furanocembranoid Substructures.
Authors: Macabeo Allan Patrick G. , Lehmann Christian W. , Reiser Oliver 
Published: April 2013

AbstractVinylogous aldol addition of 2‐siloxyfurans to cyclopropane (I) followed by tin‐ catalyzed retroaldol—lactonization cascade affords the title compounds (IV).