bluuebunny/crossref_metadata_2025_split huggingface dataset:
Case–Control Study of Maternal Residential Atrazine Exposure and Male Genital Malformations
Authors: Agopian A.J. , Lupo Philip J. , Canfield Mark A. , Langlois Peter H. 
Published: March 2013

AbstractExposure to endocrine disrupting chemicals has been associated with risk for male genital malformations. However, residential prenatal exposure to atrazine, an endocrine disrupting pesticide, has not been evaluated. We obtained data from the Texas Birth Defects Registry for 16,433 cases with isolated male genital malformations and randomly selected, population‐based controls delivered during 1999–2008. County‐level estimates of atrazine exposure from the United States Geological Survey were linked to all subjects. We evaluated the relationship between estimated maternal residential atrazine exposure and risk for male genital malformations in offspring. Separate unconditional logistic regression analyses were conducted for hypospadias, cryptorchidism, and small penis. We observed modest, but consistent, associations between medium‐low and/or medium levels of estimated periconceptional maternal residential atrazine exposure and every male genital malformation category evaluated (e.g., adjusted odds ratio for medium compared to low atrazine levels and all male genital malformations: 1.2, 95% confidence interval: 1.1–1.3). Previous literature from animal and epidemiological studies supports our findings. Our results provide further evidence of a suspected teratogenic role of atrazine. © 2013 Wiley Periodicals, Inc.
Timing of deep brain stimulation in Parkinson disease: A need for reappraisal?
Authors: deSouza Ruth‐Mary , Moro Elena , Lang Anthony E. , Schapira Anthony H. V. 
Published: March 2013

We review the current application of deep brain stimulation (DBS) in Parkinson disease (PD) and consider the evidence that earlier use of DBS confers long‐term symptomatic benefit for patients compared to best medical therapy.Electronic searches were performed of PubMed, Web of Knowledge, Embase, Cochrane Database of Systematic Reviews, and Cochrane Central Register of Controlled Trials to identify all article types relating to the timing of DBS in PD.Current evidence suggests that DBS is typically performed in late stage PD, a mean of 14 to 15 years after diagnosis. Current guidelines recommend that PD patients who are resistant to medical therapies, have significant medication side effects and lengthening off periods, but are otherwise cognitively intact and medically fit for surgery be considered for DBS.If these criteria are rigidly interpreted, it may be that, by the time medical treatment options have been exhausted, the disease has progressed to the point that the patient may no longer be fit for neurosurgical intervention. From the evidence available, we conclude that surgical management of PD alone or in combination with medical therapy results in greater improvement of motor symptoms and quality of life than medical treatment alone. There is evidence to support the use of DBS in less advanced PD and that it may be appropriate for earlier stages of the disease than for which it is currently used. The improving short and long‐term safety profile of DBS makes early application a realistic possibility. Ann Neurol 2013;73:565–575
Hydrogenated petroleum resin effect on the crystallization of isotactic polypropylene
Authors: Kang Jian , Li Jingping , Chen Shaohua , Zhu Shipeng , Li Huilin , Cao Ya , Yang Feng , Xiang Ming 
Published: March 2013

AbstractThe influence of the hydrogenated petroleum resin P125 on the crystallization behavior, crystallization kinetics, and optical properties of polypropylene (PP) were investigated. The results of differential scanning calorimetry, successive self‐nucleation, and annealing fractionation demonstrated that P125 reduced the interaction between the PP molecules, decreased the crystallization, prevented PP from forming thick lamellae, and encouraged the formation of thin lamellae. The isothermal crystallization kinetics, self‐nucleation isothermal crystallization kinetics, and polarized optical microscopy observations showed that P125 slightly decreased the nucleation rate, significantly decreased the crystal growth rate, generally reduced the overall crystallization rate, and effectively deceased the crystallite sizes of PP. The optical properties studies showed that P125 effectively decreased the haze and increased the surface glossiness and yellowness index of PP. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013
Network transformations of highly dispersed MMT/SBR nanocomposites during processing
Authors: Quan Yannan , Wang Yiqing , Wu Youping , Lu Ming , Zha Chao , Wu Xiaohui , Zhang Liqun 
Published: March 2013

AbstractA highly dispersed montmorillonite (MMT)/styrene‐butadiene rubber (SBR) nanocomposite is prepared by combining the latex compounding method and spray‐drying process. The MMT layers exhibit a nearly exfoliated structure in the spray‐dried powder. But when subjected to strains higher than 40%, the sprayed powdered nanocomposite goes through an irreversible transformation of the MMT network, showing a dramatic decrease in the storage modulus. XRD, SEM, and high resolution transmission electron microscopy results confirm the structure transformation of the MMT/SBR nanocomposite during processing. With intensive shearing during milling, the MMT layers are oriented, and further aggregations are observed in the vulcanizate. The processing procedures greatly alter the structures of the MMT/SBR nanocomposite. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013
The optical properties of PVA/TiO2 composite nanofibers
Authors: Ahmadpoor Parastoo , Nateri Ali Shams , Motaghitalab Vahid 
Published: March 2013

AbstractThe electrospun nanofibers emerge several advantages because of extremely high specific surface area and small pore size. This work studies the effect of PVA nanofibers diameter and nano‐sized TiO2 on optical properties as reflectivity of light and color of a nanostructure assembly consisting polyvinyl alcohol and titanium dioxide (PVA/TiO2) composite nanofibers prepared by electrospinning technique. The PVA/TiO2 composite spinning solution was prepared through incorporation of TiO2 nanoparticles as inorganic optical filler in polyvinyl alcohol (PVA) solution as an organic substrate using the ultrasonication method. The morphological and optical properties of collected composites nanofibers were highlighted using scanning electron microscopy (SEM) and reflective spectrophotometer (RS). The reflectance spectra indicated the less reflectance and lightness of composite with higher nanofiber diameter. Also, the reflectance and lightness of nanofibers decreased with increasing nano‐TiO2 concentration. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013
Mechanical and abrasive wear behavior of glass and basalt fabric‐reinforced epoxy composites
Authors: Chairman Chelliah Anand , Kumaresh Babu Subramani Palani 
Published: March 2013

AbstractMultipass two‐body abrasive wear behavior of basalt and glass fabric‐reinforced epoxy composites have been carried out by using a pin‐on‐disc machine. Basalt and glass fabric‐reinforced epoxy composites have been fabricated by hand layup technique. The mechanical properties of basalt and glass fabric reinforced epoxy composites were evaluated. Abrasive wear performance was evaluated at ambient temperature using 400 grade Silicon Carbide paper as a counter face. The elemental compositions of fabricated composites were quantitatively analyzed by using energy dispersive X‐ray spectroscopy. The abrading wear mechanisms have also been studied by worn surface analysis using scanning electron microscopy. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013
Modelling the distribution of the pan‐continental invasive fish Pseudorasbora parva based on landscape features in the northern Kyushu Island, Japan
Authors: Fukuda Shinji , De Baets Bernard , Onikura Norio , Nakajima Jun , Mukai Takahiko , Mouton ANS M. 
Published: March 2013

ABSTRACT

Topmouth gudgeon (Pseudorasbora parva) is widely known as a highly invasive freshwater fish and has expanded from East Asia (native range) to Central Asia, Europe and Northern Africa (introduced range). Although the relationship between the occurrence of P. parva and its habitat conditions remains unclear, information on factors affecting its distribution, especially in its native range, is important for predicting its expansion.
This study provides primary information on the distribution of P. parva in rivers and agricultural canals in northern Kyushu Island, Japan, where the fish is native. Fuzzy habitat preference models (FHPMs) and Random Forests (RF) were applied to link landscape features to the distribution of P. parva based on field observation data collected from two distinct ecoregions, the north‐western (NW) and north‐eastern (NE) parts of Kyushu Island.
The results show a clear habitat preference of P. parva for areas with a lower elevation, a gentler slope and a smaller number of river‐to‐river connections as general landscape features across the ecoregions. Weak preferences are observed for sites with a higher number of river‐to‐canal connections, a higher canal network index, a larger area of paddy fields, a larger residential area, more crop fields and fewer forests and orchards. Of these site‐specific features, five landscape features – elevation, slope, canal network index, area of paddy fields, and presence of forests and orchards – are identified as the most important features for predicting the distribution of P. parva.
The general and specific habitat preference information, as demonstrated in this study, may be important in biogeography and invasion ecology. Further research is needed to accumulate information for a better understanding of the invasion ecology and the design of improved management and control strategies against P. parva. Copyright © 2013 John Wiley & Sons, Ltd.
Group independent component analysis of MR spectra
Authors: Kalyanam Ravi , Boutte David , Gasparovic Chuck , Hutchison Kent E. , Calhoun Vince D. 
Published: March 2013

AbstractThis study investigates the potential of independent component analysis (ICA) to provide a data‐driven approach for group level analysis of magnetic resonance (MR) spectra. ICA collectively analyzes data to identify maximally independent components, each of which captures covarying resonances, including those from different metabolic sources. A comparative evaluation of the ICA approach with the more established LCModel method in analyzing two different noise‐free, artifact‐free, simulated data sets of known compositions is presented. The results from such ideal simulations demonstrate the ability of data‐driven ICA to decompose data and accurately extract components resembling modeled basis spectra from both data sets, whereas the LCModel results suffer when the underlying model deviates from assumptions, thus highlighting the sensitivity of model‐based approaches to modeling inaccuracies. Analyses with simulated data show that independent component weights are good estimates of concentrations, even of metabolites with low intensity singlet peaks, such as scyllo‐inositol. ICA is also applied to single voxel spectra from 193 subjects, without correcting for baseline variations, line‐width broadening or noise. The results provide evidence that, despite the presence of confounding artifacts, ICA can be used to analyze in vivo spectra and extract resonances of interest. ICA is a promising technique for decomposing MR spectral data into components resembling metabolite resonances, and therefore has the potential to provide a data‐driven alternative to the use of metabolite concentrations derived from curve‐fitting individual spectra in making group comparisons.
Novel Indole Alkaloids from Nauclea latifolia and Their Renin‐Inhibitory Activities
Authors: Agomuoh Anthony A. , Ata Athar , Udenigwe Chibuike C. , Aluko Rotimi E. , Irenus Iwu 
Published: March 2013

AbstractChemical studies on the crude MeOH extract of stems and barks of Nauclea latifolia resulted in the isolation of five new indole alkaloids, latifoliamides A–E (1–5, resp.), along with one known alkaloid, angustoline (6). The structures of these compounds were elucidated by means of extensive NMR spectral studies. Compound 1 has a 20‐ethylidenetetrahydrofuran ring incorporated in its structure and represents the first example of this class of indole alkaloids. All of the isolates exhibited moderate in vitro renin inhibitory activities.
Inhibitory Effects of Maleimide Derivatives from the Mycelia of the Fungus Antrodia cinnamomea BCRC 36799 on Nitric Oxide Production in Lipopolysaccharide (LPS)‐Activated RAW264.7 Macrophages
Authors: Wu Ming‐Der , Cheng Ming‐Jen , Yech Yi‐Jen , Yuan Gwo‐Fang , Chen Jih‐Jung 
Published: March 2013

AbstractFour new maleimide derivatives, antrocinnamomins E–H (1–4, resp.), together with (3S,4R)‐1‐hydroxy‐3‐(4‐hydroxyphenyl)‐4‐(2‐methylpropyl)pyrrolidine‐2,5‐dione (5) and ergosterol were isolated from the mycelia of Antrodia cinnamomea BCRC 36799. The structures were elucidated by 1D‐ and 2D‐NMR spectroscopy, and mass spectrometry. Compounds 1–5 were evaluated for their inhibitory effects on nitric oxide (NO) production by macrophages. Compounds 2 and 4 showed stronger inhibition of NO production than the positive control quercetin.
Phytochemical Investigation of Annulohypoxylon ilanense, an Endophytic Fungus Derived from Cinnamomum Species
Authors: Wu Ming‐Der , Cheng Ming‐Jen , Chen Ih‐Sheng , Su Yung‐Shun , Hsieh Sung‐Yuan , Chang Hsun‐Shuo , Chang Chun‐Wei , Yuan Gwo‐Fang 
Published: March 2013

AbstractCultivation of the fungal strain Annulohypoxylon ilanense, an endophytic fungus isolated from the wood of medicinal plant Cinnamomum species, resulted in the isolation of one new furanoid derivative, ilanefuranone (1), one new pyrrole alkaloid, ilanepyrrolal (2), and one new biarylpropanoid derivative, ilanenoid (3), together with 22 known compounds, of which one α‐tetralone analog, (−)‐(4R)‐3,4‐dihydro‐4,6‐dihydroxynaphthalen‐1(2H)‐one (4) was isolated for the first time from a natural source. The structures were elucidated on the basis of physicochemical evidence, in‐depth NMR spectroscopic analysis, and high‐resolution mass spectrometry, and the antimycobacterial activities were also evaluated.
Tetrathiafulvalene–Oligo(para‐phenyleneethynylene) Conjugates: Formation of Multiple Mixed‐Valence Complexes upon Electrochemical Oxidation
Authors: Lipnická Šárka , Bělohradský Martin , Kolivoška Viliam , Pospíšil Lubomír , Hromadová Magdaléna , Pohl Radek , Chocholoušová Jana Vacek , Vacek Jaroslav , Fiedler Jan , Stará Irena G. , Starý Ivo 
Published: March 2013

AbstractShort monodisperse oligo‐ (para‐phenyleneethynylene) (pOPE) units bearing laterally attached tetrathio‐substituted tetrathiofulvalene (TTF) units have been synthesised from functionalised aromatic building blocks by using the Sonogashira cross‐coupling methodology. The unusual redox properties of these TTF–pOPE conjugates were observed by employing electrochemical methods, such as cyclic voltammetry and exhaustive electrolysis. We found that formally one half of the TTF units in the pOPE monomer 1, dimer 2, and trimer 3 (with 2, 4, and 6 TTF units, respectively) are electrochemically silent during the first‐step oxidation at 0.49 V. We propose the formation of persistent mixed‐valence complexes from the TTF and TTF+. units present in an equal ratio. Such mixed‐valence dyads (single or multiple in the partially oxidised 1–3) exhibit an unusual stability towards oxidation until the potential of the second oxidation at 0.84 V is achieved. This finding suggests that below this potential the oxidation of the respective mix‐valence complexes is extremely slow.
ChemInform Abstract: Synthesis, Crystal Structure and Nonlinear Optical Property of CsV2O5.
Authors: Luo Hong , Pan Jianguo , Lou Bingqian , Li Yuebao , Li Xing , Han Lei 
Published: March 2013

AbstractSingle crystals of CsV2O5 are prepared by solid state reaction of stoichiometric amounts of Cs2CO3 and V2O5 (Pt crucible, 500 °C, 120 h).
ChemInform Abstract: Magnetic Structure and Properties of the Na2CoP2O7 Pyrophosphate Cathode for Sodium‐Ion Batteries: A Supersuperexchange‐Driven Non‐Collinear Antiferromagnet.
Authors: Barpanda Prabeer , Avdeev Maxim , Ling Chris D. , Lu Jiechen , Yamada Atsuo 
Published: March 2013

AbstractThe crystal and magnetic structures of the title cathode material are characterized by magnetic susceptibility, specific heat, and variable‐temperature neutron powder diffraction measurements.
ChemInform Abstract: Preparation, Crystal Structure, Electronic Structure, Impedance Spectroscopy, and Raman Spectroscopy of Li3SbS3 and Li3AsS3.
Authors: Huber Sebastian , Preitschaft Christian , Weihrich Richard , Pfitzner Arno 
Published: March 2013

AbstractSingle crystals of Li3AsS3 are prepared by a new route involving LiI as a flux.
ChemInform Abstract: Direct β‐Acyloxylation of Enamines via PhIO‐Mediated Intermolecular Oxidative C—O Bond Formation and Its Application to the Synthesis of Oxazoles.
Authors: Liu Xin , Cheng Ran , Zhao Feifei , Zhang‐Negrerie Daisy , Du Yunfei , Zhao Kang 
Published: March 2013

AbstractTreatment of enamines with carboxylic acids and PhIO allows a mild, convenient, and metal‐free access to a number of β‐acyloxy enamines.
ChemInform Abstract: Nitroxyl Radical/PhI(OAc)2: One‐Pot Oxidative Cleavage of Vicinal Diols to (Di)carboxylic Acids.
Authors: Shibuya Masatoshi , Shibuta Takuro , Fukuda Hayato , Iwabuchi Yoshiharu 
Published: March 2013

AbstractA mild and efficient method for the conversion of terminal and internal 1,2‐diols to carboxylic acids is presented which proceeds without epimerization.
ChemInform Abstract: Copper(II) Triflate Catalyzed Amination of 1,3‐Dicarbonyl Compounds.
Authors: Ton Thi My Uyen , Himawan Fanny , Chang Joyce Wei Wei , Chan Philip Wai Hong 
Published: March 2013

AbstractThe reaction is proposed to proceed via initial aziridination of the substrates enol form followed by Lewis acid‐catalyzed ring opening.
ChemInform Abstract: A Convenient Procedure for Bis‐esterification of Cyclic Anhydrides.
Authors: Jana Amit Kumar , Karmakar Raju , Dinda Bidyut Kumar , Mitra Prithiba , Ghosh Ketaki , Karmakar Rajdip , Mal Dipakranjan 
Published: March 2013

AbstractA present new method also allows the preparation of mixed dialkyl esters.
ChemInform Abstract: Enantioselective Rhodium‐Catalyzed Synthesis of Branched Allylic Amines by Intermolecular Hydroamination of Terminal Allenes.
Authors: Cooke Michael L. , Xu Kun , Breit Bernhard 
Published: March 2013

AbstractOptimized conditions allow the preparation of α‐chiral allylic amines as important synthons in organic chemistry.
ChemInform Abstract: Enantioselective Decarboxylative Michael Addition of β‐Ketoacids to Nitroalkenes Catalyzed by Binaphthyl‐Derived Organocatalysts.
Authors: Moon Hyoung Wook , Kim Dae Young 
Published: March 2013

AbstractA wide range of nitroalkenes (I) and β‐ketoacids (IV), possessing electron‐donating and electron‐withdrawing substituents on the aryl ring, undergo Michael addition reaction in the presence of a chiral bifunctional organocatalyst to afford the adducts (III) and (V) in high yields and enantioselectivities.
ChemInform Abstract: Enantiocontrolled Synthesis of Tertiary α‐Hydroxy‐α‐ynyl Esters by Dimethylzinc‐Mediated Addition of Alkynes to α‐Keto Esters.
Authors: Infante Rebeca , Gago Alfonso , Nieto Javier , Andres Celia 
Published: March 2013

AbstractA perhydro‐1,3‐benzoxazine, derived from 8‐aminomenthol, is used as a chiral ligand.
ChemInform Abstract: Rearrangements of N‐Acyl Isothioureas. Alternate Access to Acylguanidines from Cyanamides.
Authors: Maestri Giovanni , Larraufie Marie‐Helene , Ollivier Cyril , Malacria Max , Fensterbank Louis , Lacote Emmanuel 
Published: March 2013

AbstractPhotochemical reaction of diaryl disulfides with N‐acyl cyanamides and iPr2NEt proceeds with 1,3‐migration of the acyl group and provides a new approach to isothioureas.
ChemInform Abstract: N‐(Diazoacetyl)oxazolidin‐2‐thiones as Sulfur—Donor Reagents: Asymmetric Synthesis of Thiiranes from Aldehydes.
Authors: Cano Israel , Gomez‐Bengoa Enrique , Landa Aitor , Maestro Miguel , Mielgo Antonia , Olaizola Iurre , Oiarbide Mikel , Palomo Claudio 
Published: March 2013

AbstractThe ability of the oxazolidin‐2‐thione group to act as an intramolecular sulfur donor and a stereodirecting group allows the synthesis of optically active thiiranes from substrates (I), (IX) and (XI) and aldehydes.
ChemInform Abstract: A Highly Enantioselective Synthesis of Functionalized 2,3‐Dihydrofurans by a Modified Feist—Benary Reaction.
Authors: Dou Xiaowei , Zhong Fangrui , Lu Yixin 
Published: March 2013

AbstractThis method uses β‐ketoesters as substrates and a L‐threonine‐derived tertiary amine/thiourea bifunctional organocatalyst to yield functionalized 2,3‐dihydrofurans with good yields and enantioselectivities.
ChemInform Abstract: Multicomponent Synthesis of Pyrroles from Cyclopropanes: A One‐Pot Palladium(0)‐Catalyzed Dehydrocarbonylation/Dehydration.
Authors: Humenny William J. , Kyriacou Polydoros , Sapeta Katarina , Karadeolian Avedis , Kerr Michael A. 
Published: March 2013

AbstractStarting with the Yb‐catalyzed two‐component coupling of cyclopropane dicarboxylates (I) with nitrones or the analogous three‐component reaction of substrates (VII) with phenylhydrazine and aldehydes, a convenient synthesis of biologically important tetrasubstituted pyrrole units is demonstrated.
ChemInform Abstract: Facile Synthesis of Cycloalkanoindole Derivatives by aza‐Claisen Rearrangement.
Authors: Kupai Katalin , Banoczi Gergely , Hornyanszky Gabor , Kolonits Pal , Novak Lajos 
Published: March 2013

AbstractA series of new carba analogues of the acetylcholinesterase inhibiting alkaloid physostigmine are synthesized via BF3·OEt2 catalyzed cyclization reactions of cycloalkenylmethyl(aryl)amines.
ChemInform Abstract: Synthesis and Evaluation of Indole‐Containing 3,5‐Diarylisoxazoles as Potential Pro‐Apoptotic Antitumor Agents.
Authors: Md Tohid Siti Farah , Ziedan Noha I. , Stefanelli Fabio , Fogli Stefano , Westwell Andrew D. 
Published: March 2013

AbstractNovel isoxazoles containing an indole moiety are synthesized regiospecifically by either condensation reactions or dipolar cycloadditions.
ChemInform Abstract: Palladium‐Catalyzed Dehydrogenation/Oxidative Cross‐Coupling Sequence of β‐Heteroatom‐Substituted Ketones.
Authors: Moon Youngtaek , Kwon Daeil , Hong Sungwoo 
Published: March 2013

AbstractThe title sequence is studied for various heterocyclic systems such as (VII), (X), (XIII) and (XV) and leads to C‐3 functionalized systems.
ChemInform Abstract: Synthesis, Characterization and Antimicrobial Screening of Some Novel Chalcones and Their Derivatives.
Authors: Chate Asha V. , Joshi Ratnadeep S. , Mandhane Priyanka G. , Gill Charansingh 
Published: March 2013

AbstractA new series of novel chalcones (III) is synthesized and transformed into chromenone derivatives (IV) and (V) via oxidative cyclization reactions.
ChemInform Abstract: Microwave Enhanced Claisen‐Schmidt Condensation: A Green Route to Chalcones.
Authors: Singh Jayant P. , Dulawat Mangalshree , Jaitawat Neetu , Chundawat Sumer S. , Devpura Anju , Dulawat Shiv S. 
Published: March 2013

AbstractAn Environmentally benign, solvent‐free synthesis of chalcones (III) is developed.
ChemInform Abstract: Highly Enantioselective Transfer Hydrogenation of Quinolines Catalyzed by Gold Phosphates: Achiral Ligand Tuning and Chiral‐Anion Control of Stereoselectivitiy.
Authors: Tu Xi‐Feng , Gong Liu‐Zhu 
Published: March 2013

AbstractA gold phosphate complex, generated in situ, efficiently catalyzes the process.
ChemInform Abstract: Heteroaromatic Imidazo[1,2‐a]pyridines Synthesis from C—H/N—H Oxidative Cross‐Coupling/Cyclization.
Authors: He Chuan , Hao Jing , Xu Huan , Mo Yiping , Liu Huiying , Han Juanjuan , Lei Aiwen 
Published: March 2013

AbstractDerivative (VIIh) is a precursor for the preparation of the antiulcer drug Zolimidine (VIII).