bluuebunny/crossref_metadata_2025_split huggingface dataset:
All-Cause, Cardiovascular, and Cancer Mortality in Western Alaska Native People: Western Alaska Tribal Collaborative for Health (WATCH)
Authors: Howard Barbara V. , Metzger Jesse S. , Koller Kathryn R. , Jolly Stacey E. , Asay Elvin D. , Wang Hong , Wolfe Abbie W. , Hopkins Scarlett E. , Kaufmann Cristiane , Raymer Terry W. , Trimble Brian , Provost Ellen M. , Ebbesson Sven O. E. , Austin Melissa A. , Howard William James , Umans Jason G. , Boyer Bert B. 
Published: April 2014

Objectives. We determined all-cause, cardiovascular disease (CVD), and cancer mortality in western Alaska Native people and examined agreement between death certificate information and adjudicated cause of deaths. Methods. Data from 4 cohort studies were consolidated. Death certificates and medical records were reviewed and adjudicated according to standard criteria. We compared adjudicated CVD and cancer deaths with death certificates by calculating sensitivity, specificity, predictive values, and κ statistics. Results. Men (n = 2116) and women (n = 2453), aged 18 to 95 years, were followed an average of 6.7 years. The major cause of death in men was trauma (25%), followed by CVD (19%) and cancer (13%). The major cause of death in women was CVD (24%), followed by cancer (19%) and trauma (8%). Stroke rates in both genders were higher than those of US Whites. Only 56% of deaths classified as CVD by death certificate were classified as CVD by standard criteria; discordance was higher among men (55%) than women (32%; κs = 0.4 and 0.7). Conclusions. We found lower rates for coronary heart disease death but high rates of stroke mortality. Death certificates overestimated CVD mortality; concordance between the 2 methods is better for cancer mortality. The results point to the importance of cohort studies in this population in providing data to assist in health care planning.
Period Life Tables for the Non-Hispanic American Indian and Alaska Native Population, 2007–2009
Authors: Arias Elizabeth , Xu Jiaquan , Jim Melissa A. 
Published: April 2014

Objectives. We estimated complete period life tables for the non-Hispanic American Indian and Alaska Native (AI/AN) population residing in Contract Health Service Delivery Area (CHSDA) counties for the period 2007–2009. Methods. We used National Vital Statistics System mortality data files for years 2007–2009 corrected for AI/AN misclassification on death certificates, midyear 2008 revised census bridged race intercensal population estimates, and National Vital Statistics System birth data for years 2006–2009. We used the same methodology as that used to estimate official US annual life tables, with some minor modifications. Results. For the period 2007–2009, the non-Hispanic AI/AN population in CHSDA counties had the lowest life expectancy at birth (71.1 years) of any racial/ethnic group for which official US life tables are estimated. By comparison, in 2008, life expectancy at birth was 73.9 years for the non-Hispanic Black population, 78.4 years for the non-Hispanic White population, and 80.8 years for the Hispanic population. Conclusions. The life tables showed a clear mortality disadvantage for the non-Hispanic AI/AN population in CHSDA counties relative to other national populations. The findings suggested that further research is necessary to explore the causes behind these disadvantages.
American Indian Health Policy: Historical Trends and Contemporary Issues
Authors: Warne Donald , Frizzell Linda Bane 
Published: April 2014

The United States has a trust responsibility to provide services to American Indians and Alaska Native (AI/AN) persons. However, a long-standing history of underfunding of the Indian Health Service (IHS) has led to significant challenges in providing services. Twentieth century laws, including the Snyder Act, Transfer Act, Indian Self-Determination and Education Assistance Act, and Indian Health Care Improvement Act (IHCIA) have had an effect on the way health services are provided. IHCIA was reauthorized as part of the Patient Protection and Affordable Care Act (ACA). Several provisions in ACA allow for potential improvements in access to services for AI/AN populations and are described herein. Although policy developments have been promising, IHS underfunding must be resolved to ensure improved AI/AN health.
Methods for Improving the Quality and Completeness of Mortality Data for American Indians and Alaska Natives
Authors: Espey David K. , Jim Melissa A. , Richards Thomas B. , Begay Crystal , Haverkamp Don , Roberts Diana 
Published: April 2014

Objectives. We describe methods used to mitigate the effect of race misclassification in mortality records and the data sets used to improve mortality estimates for American Indians and Alaska Natives (AI/ANs). Methods. We linked US National Death Index (NDI) records with Indian Health Service (IHS) registration records to identify AI/AN deaths misclassified as non-AI/AN deaths. Analyses excluded decedents of Hispanic origin and focused on Contract Health Service Delivery Area (CHSDA) counties. We compared death rates for AI/AN persons and Whites across 6 US regions. Results. IHS registration records merged to 176 137 NDI records. Misclassification of AI/AN race in mortality data ranged from 6.3% in the Southwest to 35.6% in the Southern Plains. From 1999 to 2009, the all-cause death rate in CHSDA counties for AI/AN persons varied by geographic region and was 46% greater than that for Whites. Analyses for CHSDA counties resulted in higher death rates for AI/AN persons than in all counties combined. Conclusions. Improving race classification among AI/AN decedents strengthens AI/AN mortality data, and analyzing deaths by geographic region can aid in planning, implementation, and evaluation of efforts to reduce health disparities in this population.
Infectious Disease Mortality Among American Indians and Alaska Natives, 1999–2009
Authors: Cheek James E. , Holman Robert C. , Redd John T. , Haberling Dana , Hennessy Thomas W. 
Published: April 2014

Objectives. We described death rates and leading causes of death caused by infectious diseases (IDs) in American Indian/Alaska Native (AI/AN) persons. Methods. We analyzed national mortality data, adjusted for AI/AN race by linkage with Indian Health Service registration records, for all US counties and Contract Health Service Delivery Area (CHSDA) counties. The average annual 1999 to 2009 ID death rates per 100 000 persons for AI/AN persons were compared with corresponding rates for Whites. Results. The ID death rate in AI/AN populations was significantly higher than that of Whites. A reported 8429 ID deaths (rate 86.2) in CHSDA counties occurred among AI/AN persons; the rate was significantly higher than the rate in Whites (44.0; rate ratio [RR] = 1.96; 95% confidence interval [CI] = 1.91, 2.00). The rates for the top 10 ID underlying causes of death were significantly higher for AI/AN persons than those for Whites. Lower respiratory tract infection and septicemia were the top-ranked causes. The greatest relative rate disparity was for tuberculosis (RR = 13.51; 95% CI = 11.36, 15.93). Conclusions. Health equity might be furthered by expansion of interventions to reduce IDs among AI/AN communities.
Adapting to the Effects of Climate Change on Inuit Health
Authors: Ford James D. , Willox Ashlee Cunsolo , Chatwood Susan , Furgal Christopher , Harper Sherilee , Mauro Ian , Pearce Tristan 
Published: April 2014

Climate change will have far-reaching implications for Inuit health. Focusing on adaptation offers a proactive approach for managing climate-related health risks—one that views Inuit populations as active agents in planning and responding at household, community, and regional levels. Adaptation can direct attention to the root causes of climate vulnerability and emphasize the importance of traditional knowledge regarding environmental change and adaptive strategies. An evidence base on adaptation options and processes for Inuit regions is currently lacking, however, thus constraining climate policy development. In this article, we tackled this deficit, drawing upon our understanding of the determinants of health vulnerability to climate change in Canada to propose key considerations for adaptation decision-making in an Inuit context.
Pneumonia and Influenza Mortality Among American Indian and Alaska Native People, 1990–2009
Authors: Groom Amy V. , Hennessy Thomas W. , Singleton Rosalyn J. , Butler Jay C. , Holve Stephen , Cheek James E. 
Published: April 2014

Objectives. We compared pneumonia and influenza death rates among American Indian/Alaska Native (AI/AN) people with rates among Whites and examined geographic differences in pneumonia and influenza death rates for AI/AN persons. Methods. We adjusted National Vital Statistics Surveillance mortality data for racial misclassification of AI/AN people through linkages with Indian Health Service (IHS) registration records. Pneumonia and influenza deaths were defined as those who died from 1990 through 1998 and 1999 through 2009 according to codes for pneumonia and influenza from the International Classification of Diseases, 9th and 10th Revision, respectively. We limited the analysis to IHS Contract Health Service Delivery Area counties, and compared pneumonia and influenza death rates between AI/ANs and Whites by calculating rate ratios for the 2 periods. Results. Compared with Whites, the pneumonia and influenza death rate for AI/AN persons in both periods was significantly higher. AI/AN populations in the Alaska, Northern Plains, and Southwest regions had rates more than 2 times higher than those of Whites. The pneumonia and influenza death rate for AI/AN populations decreased from 39.6 in 1999 to 2003 to 33.9 in 2004 to 2009. Conclusions. Although progress has been made in reducing pneumonia and influenza mortality, disparities between AI/AN persons and Whites persist. Strategies to improve vaccination coverage and address risk factors that contribute to pneumonia and influenza mortality are needed.
Suicide Mortality Among American Indians and Alaska Natives, 1999–2009
Authors: Herne Mose A. , Bartholomew Michael L. , Weahkee Rose L. 
Published: April 2014

Objectives. We assessed national and regional suicide mortality for American Indian and Alaska Native (AI/AN) persons. Methods. We used 1999 to 2009 death certificate data linked with Indian Health Service (IHS) patient registration data to examine death rates from suicide in AI/AN and White persons. Analysis focused primarily on residents of IHS Contract Health Service Delivery Area counties; Hispanics were excluded. We used age-adjusted death rates per 100 000 population and stratified our analyses by age and IHS region. Results. Death rates from suicide were approximately 50% higher among AI/AN persons (21.2) than Whites (14.2). By region, rates for AI/AN people were highest in Alaska (rates = 65.4 and 19.3, for males and females, respectively) and in the Northern Plains (rates = 41.6 and 11.9 for males and females, respectively). Disparities between AI/AN and White rates were also highest in these regions. Conclusions. A coordinated, multidisciplinary effort involving federal, state, local, and tribal health officials is needed to address this important public health issue.
Overnight Closed-Loop Insulin Delivery in Young People With Type 1 Diabetes: A Free-Living, Randomized Clinical Trial
Authors: Hovorka Roman , Elleri Daniela , Thabit Hood , Allen Janet M. , Leelarathna Lalantha , El-Khairi Ranna , Kumareswaran Kavita , Caldwell Karen , Calhoun Peter , Kollman Craig , Murphy Helen R. , Acerini Carlo L. , Wilinska Malgorzata E. , Nodale Marianna , Dunger David B. 
Published: April 2014

OBJECTIVE
To evaluate feasibility, safety, and efficacy of overnight closed-loop insulin delivery in free-living youth with type 1 diabetes.

RESEARCH DESIGN AND METHODS
Overnight closed loop was evaluated at home by 16 pump-treated adolescents with type 1 diabetes aged 12–18 years. Over a 3-week period, overnight insulin delivery was directed by a closed-loop system, and on another 3-week period sensor-augmented therapy was applied. The order of interventions was random. The primary end point was time when adjusted sensor glucose was between 3.9 and 8.0 mmol/L from 2300 to 0700 h.

RESULTS
Closed loop was constantly applied over at least 4 h on 269 nights (80%); sensor data were collected over at least 4 h on 282 control nights (84%). Closed loop increased time spent with glucose in target by a median 15% (interquartile range −9 to 43; P &lt; 0.001). Mean overnight glucose was reduced by a mean 14 (SD 58) mg/dL (P &lt; 0.001). Time when glucose was &lt;70 mg/dL was low in both groups, but nights with glucose &lt;63 mg/dL for at least 20 min were less frequent during closed loop (10 vs. 17%; P = 0.01). Despite lower total daily insulin doses by a median 2.3 (interquartile range −4.7 to 9.3) units (P = 0.009), overall 24-h glucose was reduced by a mean 9 (SD 41) mg/dL (P = 0.006) during closed loop.

CONCLUSIONS
Unsupervised home use of overnight closed loop in adolescents with type 1 diabetes is safe and feasible. Glucose control was improved during the day and night with fewer episodes of nocturnal hypoglycemia.
Electro-osmotically actuated oscillatory flow of a physiological fluid on a porous microchannel subject to an external AC electric field having dissimilar frequencies
Authors: Misra Jagadis , Chandra Sukumar 
Published: April 2014

AbstractElectro-osmotic flow of a physiological fluid with prominent micropolar characteristics, flowing over a microchannel has been analyzed for a situation, where the system is subject to the action of an external AC electric field. In order to account for the rotation of the micro-particles suspended in the physiological fluid, the fluid has been treated as a micropolar fluid. The microchannel is considered to be bounded by two porous plates executing oscillatory motion. Such motion of the plates will normally induce oscillatory flow of the fluid. The governing equations of the fluid include a second-order partial differential equation depicting Gauss’s law of electrical charge distributions and two other partial differential equations of second order that arise out of the laws of conservation of linear and angular momenta. These equations have been solved under the sole influence of electrokinetic forces, by using appropriate boundary conditions. This enabled us to determine explicit analytical expressions for the electro-osmotic velocity of the fluid and the microrotation of the suspended micro-particles. These expressions have been used to obtain numerical estimates of important physical variables associated with the oscillatory electro-osmotic flow of a blood sample inside a micro-bio-fluidic device. The numerical results presented in graphical form clearly indicate that the formation of an electrical double layer near the vicinity of the wall causes linear momentum to reduce. In contrast, the angular momentum increases with the enhancement of microrotation of the suspended microparticles. The study will find important applications in the validation of results of further experimental and numerical models pertaining to flow in micro-bio-fluidic devices. It will also be useful in the improvement of the design and construction of various micro-bio-fluidic devices.
Molecular Identification Virulence Genes Of Escherichia coli Isolated From Bovine Clinical Mastitis
Authors: Moradli Gholam Ali , Salehii Tagi Zahraei , Jamshidian Mahmod , Mosakhani Farhad 
Published: April 2014

The aims of this study were molecular identification some of virulence genes in Escherichia coli isolated from milk of bovines with clinical mastitis. (n = 60) E. coli isolates from acute clinical mastitis were examined for detect the presence of the genes encodingshigatoxin1 (stx1), intimin (eaeA), cytotoxicnecrotizingfactor 2 (cnf2), aerobactin (iucD) and P fimberiae (pap). The majors finding in the PCR assays were: 8 isolates (13.33%) had at least one virulence gene, None of isolates contained the genes for stx1, eaeA , the most common gene in the examined isolate was iucD which was positive in 6 isolates (10%). One isolate (1.66%) was positive for both iucD and pap genes and one isolate (1.66%) for cnf2 gene. In this study similar to previous investigations indicated that prevalence virulence genes in E. coli isolated of bovine mastitis is deferent. The results of this investigate similar to previous studies indicated none of the potential virulence genes or specific pathotype was observed in E. coli isolates from bovine clinical mastitis. DOI: http://dx.doi.org/10.3126/ijls.v8i2.10219 International Journal of Life Sciences Vol.8(2): 2014; 1-3
Work related injuries and musculoskeletal disorders among child workers in the brick kilns of Nepal
Authors: Joshi Sunil Kumar , Dahal Pranab , Poudel Agya , Sherpa Helen 
Published: April 2014

Brick manufacturing is a labor intensive informal industry using child workers as the major work force in Nepal. Workers are required to use physical strength, carry heavy loads and remain in a squatted posture for longer periods doing repetitive tasks posing threats to musculoskeletal system. This study involved cross sectional study of children aged 17 years and below. The study respondent included 101 cases and 64 controls in Bhaktapur and 97 cases and 43 controls in Sarlahi. Lack of adequate physical infrastructures, poor working conditions with non existent safety procedures have posed risk to physical, metal and overall well being of children. The study identifies work related physical ailments and discomforts dominate brick industries of Nepal. The musculoskeletal disorder related pain and discomfort was experienced by 73 per cent of working children in Bhaktapur and 58 per cent in Sarlahi. The odds ratio suggests that working children were 8 times more likely to experience trouble or body pain compared to non-working children. This study finds that presence of inferior physical environment, working conditions and practices has contributed to musculoskeletal injuries and problems exposing working children to risks and hazards. DOI: http://dx.doi.org/10.3126/ijosh.v3i2.10271
Assessment of Dental caries status, Periodontal health and oral hygiene practices among two Populations of Moradabad city, India
Authors: Tirth Amit , Yadav Vipul , Tangade Pradeep S , Ravishankar TL , Chaudhary Sunil , Mathur Anmol 
Published: April 2014

Background: Ever since the beginning of the universe mankind had struggled constantly for their livelihood, Moradabad is branded as the “Brass city” of India, which comprises of a large number of populations working in different industries. Objective: To assess and compare the oral health status of workers employed in brass industries with non industrial workers of Moradabad city. Material and Methods: A total of 500 workers from each group aged 30-50 with 5 years working experience were selected through random sampling. Type III examination was performed by recording who oral health assessment form. To compare the proportion chi-square test was used. Mean values were compared using students t-test. SPSS version 15.0 was used for statistical analyses. Results: The prevalence of dental caries as Mean DMFT score was significantly higher in Non Industrial Group i.e. 3.57±2.74 while it was 2.88±2.14 in brass workers. Periodontal diseases were higher among production workers that belong to brass industries. The prevalence of Oral Mucosal Lesions was significantly higher among Production Workers. Bleeding was more pronounced in general population but calculus and pockets were seen more in brass workers. The requirement of prosthetic status was also more prevalent among industry subjects. Conclusion: The Oral health status of Brass Industry Workers was relatively poor with poor periodontal health when compared to General Population. Further studies of oral occupational disease should be conducted in order to check or confirm previous reports and to discover possible manifestations arising in new industries.DOI: http://dx.doi.org/10.3126/ijosh.v3i2.6312
Work-Related Stress and Substance Use as Risk Factors for Chronic Disease Among Three-Wheel Drivers in Galle, Sri Lanka: A Qualitative Study
Authors: Kirkorowicz JM , Sapukotana P , De Silva PV , Noda M , De Oliveira JS , Østbye T 
Published: April 2014

Background: Motor three-wheel drivers provide an important means of transportation in Sri Lanka, comprising 15% of motorized road vehicles. Although three-wheel driving is a widespread occupation for Sri Lankan men, little is known about their general health or risk factors.Objectives: This paper investigates chronic illnesses and risk factors for such illnesses in a sample of 33 three-wheel drivers in Galle, Sri Lanka.Methods: A qualitative investigation was conducted between June and August 2012. 20 three-wheel drivers participated in 60-minute semi-structured interviews, and 13 participated in semi- structured focus groups related to their work-related health concerns.Results: Illness reported included musculoskeletal pain, hypercholesteremia, hypertension, and diabetes. Participants identified work-related stress and substance abuse as risk factors.Conclusions: Participants described a cycle of work related stress, substance use, and chronic illness. Community-based education on the risks of substance use and alternative means of coping may be an effective intervention for these workers. DOI: http://dx.doi.org/10.3126/ijosh.v3i2.7662
Magnitude and Characteristics of Occupational injury in Kombolcha textile factory, North East Ethiopia
Authors: Yessuf Serkalem S , Moges Haimanot Gebrehiwot , Ahmed Ansha N 
Published: April 2014

Background: Working environment is one of the factors which can determine public health conditions as many workers spend a large portion of their time at work.Objective: The aim of this study was to assess the magnitude and characteristics of occupational injury among workers in Kombolcha textile factory, North East Ethiopia.Methods: Institution based cross-sectional study design was conducted from April1-15, 2013 among 455 randomly selected workers after stratification by working departments. A structured questionnaire based interview, review of records of injury report and walk through survey using work environment observation checklist were used to support the self-reported information. Descriptive statistics were used for analysis using SPSS version 20.Results: The overall occupational injury prevalence rate was 36.9%. Puncture, abrasion/laceration, fracture, cut and back pain were the most common types of injury. Most of the sources of injury were due to machinery, lifting heavy objects, splinters, fall and hand tools.Conclusion: The magnitude of occupational injury at Kombolcha textile industry showed a high prevalence that indicates the need to work on integrated injury prevention by mainstreaming occupational health and safety procedures in all working departments of the factory. DOI: http://dx.doi.org/10.3126/ijosh.v3i2.8381