bluuebunny/crossref_metadata_2025_split huggingface dataset:
Risk for symptomatic hemorrhage of cerebral cavernous malformations during pregnancy
Authors: Kalani M. Yashar S. , Zabramski Joseph M. 
Published: October 2012

Object
The threat of symptomatic hemorrhage from cerebral cavernous malformations (CCMs) during pregnancy remains poorly understood. The authors undertook this study to better define the risk of pregnancy-related hemorrhage in this population.

Methods
The records of female patients with sporadic (isolated lesions and negative family history) and familial forms of CCM, which were collected as part of the Barrow Neurological Institute CCM natural history study, were examined. Clinical data related to pregnancy, including type of delivery (vaginal or cesarean section) and any change in neurological status, were obtained from chart reviews and patient interviews.

Results
There were 168 pregnancies among 64 female patients with CCM (28 sporadic and 36 familial). Assuming an average of 46 weeks per pregnancy (40 weeks of gestation and 6 weeks of puerperium), patients were at risk for hemorrhage for a total of 148.6 years. Symptomatic hemorrhage (defined as new-onset or exacerbation of seizure activity or any change in neurological status) occurred during 5 pregnancies, with the most common symptom being seizures (4 cases). The overall risk for symptomatic hemorrhage was 3% per pregnancy; the risk was 1.8% per pregnancy in the sporadic group and 3.6% per pregnancy in the familial patients.
There were 19 deliveries by cesarean section: 5 for obstetrical reasons, 8 for fear of possible hemorrhage, and 6 for unknown reasons. Vaginal delivery was performed without complications for the remaining 149 pregnancies.

Conclusions
The authors' experience suggests that the risk of symptomatic hemorrhage from a CCM during pregnancy is not increased and that a history of CCM is not a contraindication to pregnancy or vaginal delivery.
Rome ou la solution à tous les problèmes européens : Georg Moenius et le concept de romanité durant l´entre-deux-guerres
Authors: Lehnert Joris 
Published: October 2012

Cet article se propose d´étudier l´interprétation par le prêtre allemand Georg Moenius (1890-1953) de la religion catholique romaine comme instrument nécessaire à la restauration spirituelle de l´Occident – de la civilisation européenne – la crise de l’Europe de l’entre-deux-guerres. Pacifiste et pourfendeur acharné de tout nationalisme (et en particulier du national-socialisme), il se mit en congé de son diocèse et livra, grâce à des relations de voyages en Italie et en France, une ébauche de sa pensée. A partir de 1929 éditeur de l´hebdomadaire catholiques munichois Allgemeine Rundschau, il s’employa, grâce à cette « arme intellectuelle » et jusqu'à son exil provoqué par l’arrivé d’Hitler au pouvoir, à diffuser et expliquer la nécessité de la Romanitas proposée par Gonzague de Reynold. Admirateur de Maurras, fréquentant les milieux de l’Action française lors de ses séjours parisiens, il traduisit également l’ouvrage programmatique d’Henri Massis, Défense de l’Occident qu’il accompagna d’une longue introduction. Celle-ci présentait à la manière d’un véritable manifeste le retour à l’esprit du Saint Empire Romain Germanique médiéval, spirituellement dirigé par Rome, comme la solution à tous les problèmes de l’Europe.
Spatialisation de la biodiversité en Amazonie brésilienne pour appréhender l’influence de la colonisation des terres et des politiques publiques
Authors: Laques Anne-Elisabeth , Mitja Danielle , Delaître Eric , Thales Marcelo Cordeiro , Miranda Izildinha de Souza , Coelho Roberta de Fátima Rodrigues , Sampaio Sandra Maria Neiva 
Published: October 2012

Cet article propose une démarche de suivi des dynamiques spatiales de la biodiversité survenues durant ces 40 dernières années en Amazonie brésilienne, dans la communauté agricole de Benfica (État du Pará). Elle est conçue pour estimer « où » se produisent les changements, « quand » interviennent-ils, « combien » de surfaces sont concernées et « pourquoi » surviennent-ils ? L’objectif visé est de contribuer à l’évaluation de l’impact de politiques de colonisation sur ces dynamiques. Les données produites à la fois sur les disparités spatiales et sur les rythmes de ces transformations sont un apport qui devrait enrichir les connaissances sur l’évolution de la biodiversité en région pionnière. En l’état actuel des recherches, la démarche propose d’évaluer la biodiversité en ayant recours à une échelle de valeurs combinant plusieurs indicateurs. Chacun d’eux contribue à estimer des changements qui se produisent lors de la mise en culture des terres forestières. La biodiversité est ensuite évaluée à deux niveaux : celui des différentes formes d’exploitation des ressources en rapportant la mesure de biodiversité au niveau du composant paysager (forêt, jachère et culture/pâturage) et celui de la catégorie d’acteur (du colon au petit fermier), en rapportant la mesure de biodiversité à l’unité de territoire qu’ils exploitent préférentiellement. Le procédé de suivi de ce territoire est aisément reconductible dans le temps. En effet, il ne dépend que de la disponibilité des images satellites. Bien que cette démarche soit en cours de validation, elle devrait pouvoir être réutilisée dans d’autres régions forestières anthropisées.
Single-Lesion Skin Cancer Risk Stratification Triage Pathway
Authors: Chen Yiqun , Gui Haiwen , Yao Hanqi , Adu-Brimpong Joel , Javitz Sigi , Golovko Val , Ko Justin , Daneshjou Roxana , Chiou Albert S. 
Published: June 2024

ImportanceAccess to timely dermatologic care remains a challenge, especially for patients with new skin lesions. Assessing the efficiency of new triage pathways may assist in better resource allocation and shorter time to care.ObjectiveTo evaluate whether a rule-based triage system was associated with better skin cancer risk stratification of patients and reduced wait times.Design, Setting, and ParticipantsThis retrospective quality improvement cohort study of patients referred to Stanford University dermatology clinics was conducted between November 2017 and January 2023. A rules-based triage system based on a priori–determined high-risk lesion characteristics was implemented.ExposuresReferral reasons and risk factors of patients provided by their primary care physicians.Main Outcomes and MeasuresBiopsy results of patients (diagnosis of any skin cancer and melanoma) at their visit or within 6 months after the visit. Regression models were used to assess the association between risk factors at referral and (1) biopsy outcomes and (2) time to first visit, adjusting for sociodemographic factors.ResultsAmong 37 478 patients (mean [SD] age, 54 (18) years; 21 292 women [57%]), the rates of aggregate biopsy, malignant biopsy specimens, and melanoma were comparable across patients seen after (n = 12 302) and before (n = 25 176) the implementation of the new triage pathway. Patients seen through the lesion pathway had a higher risk of having malignant biopsy results (adjusted risk ratio [aRR], 1.6; 95% CI, 1.4-1.9) and melanoma (aRR, 2.0; 95% CI, 1.2-3.2) than those not seen through the pathway. Lesions that were concerning to referring clinicians for skin cancer were associated with an increased risk of skin cancer (all skin cancer: aRR, 2.8; 95% CI, 2.2-3.5; melanoma: aRR, 2.02; 95% CI, 1.1-3.7). Patients in the 3 high-risk lesion groups were seen faster in the new triage pathway (mean reduction, 26 days; 95% CI, 18-34 days).Conclusions and RelevanceIn this study, a new automated, rules-based referral pathway was implemented that expedited care for patients with high-risk skin cancer. This reform may have contributed to improving patient stratification, reducing the time from referral to first encounter, and maintaining accuracy in identifying malignant lesions. The findings highlight the potential to optimize clinical resource allocation by better risk stratification of referred patients.
Acupuncture and Sleep Quality Among Patients With Parkinson Disease
Authors: Yan Mingyue , Fan Jingqi , Liu Xin , Li Yingjia , Wang Yuting , Tan Weiqiang , Chen Yuanyuan , He Jun , Zhuang Lixing 
Published: June 2024

ImportancePoor sleep quality greatly impairs quality of life and accelerates deterioration in patients with Parkinson disease (PD), but current remedies remain limited. Acupuncture, used as an adjunctive therapy with anti-Parkinson medications, has shown positive effects in patients with PD. However, high-quality clinical evidence to support the effectiveness of acupuncture for patients with PD and poor sleep quality is lacking.ObjectiveTo assess the safety and efficacy of real acupuncture (RA) vs sham acupuncture (SA) as an adjunctive therapy for patients with PD who have poor sleep quality.Design, Setting, and ParticipantsThis single-center randomized clinical trial was performed at The First Affiliated Hospital of Guangzhou University of Chinese Medicine in China from February 18, 2022, to February 18, 2023. Patients with PD and sleep complaints were recruited and randomized (1:1) to receive RA or SA treatment for 4 weeks. Data analysis was performed from April 12 to August 17, 2023.InterventionTreatment with RA or SA for 4 weeks.Main Outcomes and MeasuresThe main outcome was the change in Parkinson Disease Sleep Scale (PDSS) scores measured at baseline, after 4 weeks of treatment, and at 8 weeks of follow-up.ResultsOf the 83 participants enrolled, 78 (94.0%) completed the intervention and were included in the analysis. Their mean (SD) age was 64.1 (7.9) years; 41 (52.6%) were men and 37 (47.4%) were women. A significant increase in PDSS scores from baseline was observed for both the RA group (29.65 [95% CI, 24.65-34.65]; P &amp;lt; .001) and the SA group (10.47 [95% CI, 5.35-15.60]; P &amp;lt; .001). Compared with the SA group, the RA group had a significant increase in PDSS scores after 4 weeks of treatment (19.75 [95% CI, 11.02-28.49]; P &amp;lt; .001) and at 8 weeks of follow-up (20.24 [95% CI, 11.51-28.98]; P &amp;lt; .001).Conclusions and RelevanceIn this randomized clinical trial, acupuncture proved beneficial in improving sleep quality and quality of life among patients with PD. These findings suggest that the therapeutic effects of acupuncture could continue for up to 4 weeks.Trial RegistrationChinese Clinical Trial Registry Identifier: ChiCTR2200060655
Design and control of radiant heating and cooling systems in Japan: Results from expert interviews
Authors: Shindo Kan , Ikai Ken , Shinoda Jun , Matsumura Ryota , Tanabe Shin‐ichi 
Published: June 2024

AbstractThis research conducted investigations of buildings equipped with radiant systems and expert interviews in 2021–2022 with manufacturers and mechanical, electrical, and plumbing (MEP) engineers in Japan who had experience designing radiant heating and cooling systems for non‐residential buildings. In total, interviews were conducted with 56 respondents from 16 companies. Results from the building investigation showed that 69% of the identified buildings had radiant ceilings, and 30% had radiant floors. In terms of working fluid, 56% were water‐based, and 43% were air‐based. For the expert interview, 79% of all respondents answered that the use of radiant systems will continue to increase in the future. In total, 54% of all respondents answered that it has become easier to design radiant systems at present compared to the 2010s. Based on the results, knowledge gaps and challenges in the design of radiant systems were summarized in terms of design method, room temperature control, auxiliary systems, and their relevance to building decarbonization.
Structural Diversity and Specificities within the Ferredoxin‐Disulfide/Thioredoxin Reductase Family
Authors: Rouhier Nicolas , Didierjean Claude 
Published: June 2024

Abstract
Ferredoxin–thioredoxin reductases (FTRs) and ferredoxin–disulfide reductases (FDRs) are relatively small enzymes that reduce the disulfide bond of redoxins. While most oxygenic photosynthetic organisms possess FTRs, FDRs are found in a variety of nonphotosynthetic prokaryotes. The catalytic center consists of a [4Fe‐4S] cluster and a redox‐active disulfide. FTRs are heterodimers formed by a catalytic subunit associated with a variable subunit. The latter is not present in FDRs. Instead, in some microorganisms, FDRs are fused to additional domains, notably rubredoxin or thioredoxin/glutaredoxin, which donate or accept electrons, respectively. This article reviews the state of the art in the structure–function relationships for this family of enzymes, describing their occurrence, catalytic mechanism, structural properties, and outstanding issues.
UAVgroup control protocol with adaptive consensus
Authors: Kucherov Dmytro P. , Jiang Guodong , Liu Huaqing , Fu Minglei 
Published: June 2024

SummaryIn this paper, a modified consensus protocol algorithm is proposed for controlling a group of identical unmanned aerial vehicles (UAVs), which have been subjected to interfering signals during coordinate information exchange, using an unknown parameter in the consensus protocol. The maximum levels of interfering signals in the proposed protocol were adjusted by incorporating a hysteresis function with a dead zone consistent with the initial coordinates and the interfering signal levels. An adaptation algorithm is proposed to address a priori uncertainty regarding the consensus parameters, involving the correction of an unknown parameter by eliminating control signals exhibiting false sign changes. This correction relies on the coordinates in the phase plane, indicating that the delay in maneuver execution occurs at the beginning of the maneuver. Furthermore, by modeling synchronized motion, UAV group consensus is demonstrated for an ideal case devoid of a priori uncertainty regarding control protocol parameters, interfering signals, or consequences. The convergence of the adaptation algorithm was assessed by defining a vector function to track parameter changes during tuning. The monotonically decreasing nature of the resulting curve, along with the finite duration of the tuning process, provides confirmation of the convergence of the adaptation algorithm.
In Situ Amorphization of Electrocatalysts
Authors: Meng Huishan , Chen Zhijie , Zhu Jinliang , You Bo , Ma Tianyi , Wei Wei , Vernuccio Sergio , Xu Juan , Ni Bing‐Jie 
Published: June 2024

AbstractElectrocatalysis represents an efficient and eco‐friendly approach to energy conversion, enabling the sustainable synthesis of valuable chemicals and fuels. The deliberate engineering of electrocatalysts is crucial to improving the efficacy and scalability of electrocatalysis. Notably, the occurrence of in situ amorphization within electrocatalysts has been observed during various electrochemical processes, influencing the energy conversion efficiency and catalytic mechanism understanding. Of note, the dynamic transformation of catalysts into amorphous structures is complex, often leading to various amorphous configurations. Therefore, revealing this amorphization process and understanding the function of amorphous species are pivotal for elucidating the structure‐activity relationship of electrocatalysts, which will direct the creation of highly efficient catalysts. This review examines the mechanisms behind amorphous structure formation, summarizes characterization methods for detecting amorphous species, and discusses strategies for controlling (pre)catalyst properties and electrochemical conditions that influence amorphization. It also emphasizes the importance of spontaneously formed amorphous species in electrochemical oxidation and reduction reactions. Finally, it addresses challenges in the in situ amorphization of electrocatalysts. aiming to guide the synthesis of electrocatalysts for efficient, selective, and stable electrochemical reactions, and to inspire future advancements in the field.
Control Over Nitrogen Dopant Sites in Palladium Metallene for Manipulating Catalytic Activity and Stability in the Oxygen Reduction Reaction
Authors: Zeng Tiantian , Niu Mang , Xu Binghui , Yuan Weiyong , Guo Chun Xian , Cao Dapeng , Li Chang Ming , Zhang Lian Ying , Zhao Xiu Song 
Published: June 2024

AbstractDoping light elements in Pt‐group metals is an effective approach toward improving their catalytic properties for oxygen reduction reaction (ORR). However, it is challenging to control dopant sites and to establish the correlation between the doping site and the catalytic property. In this paper, this success is demonstrated in controlling N doping sites in Pd metallene to manipulate electrocatalytic properties toward ORR. A Pd metallene sample with N dopant predominantly located at the atomic vacancy site (V‐N‐Pd metallene) exhibits two times higher mass activity in ORR than a Pd metallene sample with N dopant mainly occupied the interstitial site (I‐N‐Pd metallene). However, the I‐N‐Pd metallene shows improved durability than the V‐N‐Pd metallene, with only a 4 mV decay in half‐wave potential after 20 000 cycles. Computational calculation results reveal that the significantly enhanced ORR activity of V‐N‐Pd metallene arises from the atomic vacancy‐doped N, which modulates the electronic structure of Pd metallene to weaken the adsorption energy of intermediate O* species. This work provides guidelines for manipulating catalytic properties by controlling the doping sites of light elements in metal nanostructures.
Ultrafast Dynamics of Bloch Surface Wave Polaritons in Large‐Area 2D Semiconductor Monolayers at Room Temperature
Authors: Liu Bin , Michail Evripidis , He Guiying , Sfeir Matthew Y. , Forrest Stephen R. 
Published: June 2024

AbstractThe dynamics of strongly coupled polariton systems integrated with 2D transition metal dichalcogenides (TMDs) is key to enabling efficient coherent processes and achieving high‐performance TMD‐based polaritonic devices, such as ultralow‐threshold polariton lasers and ultrafast optical switches. However, there has been a lack of a comprehensive understanding of the excited state dynamics in TMD‐based polariton systems. In this work, ultrafast pump‐probe optical spectroscopy is used to investigate the room temperature dynamics of the polariton systems consisting of TMD monolayer excitons strongly coupled with Bloch surface waves (BSWs) supported by all‐dielectric photonic structures. The transient response is found for both above‐exciton energy pumping and polariton‐resonant pumping. The excited state population and ultrafast coherent coupling of the exciton reservoir and lower polariton (LP) branch are observed for resonant pumping. Moreover, it is found that the transient response of the LP first decays on a short‐time scale of 0.15–0.25 ps compared to the calculated intrinsic lifetime of 0.11–0.20 ps, and is followed by a longer decay (>100 ps) due to the dynamical evolution of the exciton reservoir. The results provide a fundamental understanding of the dynamics of TMD‐based polariton systems while showing the potential for achieving efficient coherent optical processes for device applications.
Synthesis and Emission Dynamics of Sub‐3 nm Upconversion Nanoparticles
Authors: Amouroux Baptiste , Eftekhari Ali , Roux Clément , Micheau Jean‐Claude , Roblin Pierre , Pasturel Mathieu , Gauffre Fabienne , Würth Christian , Resch‐Genger Ute , Sliwa Michel , Bouchet Aude , Coudret Christophe 
Published: June 2024

AbstractReducing the size of upconversion nanoparticles (UCNPs) down to a few nm yields luminescent materials containing a very small number of emitters. Considering the bottom limit of one activator per particle ultrasmall UCNPs offer an unprecedented platform to study the contributions of the different energy transfers at play in upconversion luminescence. Maintaining detectable emission despite the limited number of emitting ions and the high surface‐to‐volume ratio requires suitable particle architectures. Na(Gd‐Yb)F4:Tm3+ emissive sub‐3 nm diameter β‐phase UCNPs are prepared using a gadolinium‐rich composition in situ mixing of the precursors and a microwave high‐temperature cycling sequence allowing precise control of the particle size and dispersity. These cores are coated with a NaGdF4 inert shell to minimize the deleterious influence of surface quenching (SQ). Time‐resolved luminescence measurements combining standard NIR excitation of the Yb3+ sensitizer and direct UV excitation of the Tm3+ activator are performed to quantify cross relaxation and surface quenching processes. The fine tuning of the number of activators per particle via an optimized synthesis pathway along with the use of an appropriate excitation scheme enabled to provide an accurate analysis of the different mechanisms at play in these model nanoparticles and to characterize the structure of the core‐shell architecture.
Nucleophilic Cyanation of Enones and Imines with Formamide as the Cyano Source
Authors: Luo Lei , Dai Hong , Yang Ming‐Qing , Yang Luo 
Published: June 2024

AbstractA convenient cyano source for the nucleophilic 1,4‐addition to enones and 1,2‐addition to imines has been developed, by generating the cyano unit in situ. via the TCT‐assisted dehydration of formamide. This protocol distinguishes itself by transition‐metal/ligand free conditions, compatibility with 1,4‐/1,2‐addition, readily available substrates and versatile synthetic utilities of the cyanated products.
Construction of High‐Performance Anode of Potassium‐Ion Batteries by Stripping Covalent Triazine Frameworks with Molten Salt
Authors: Zhang Jingyi , Fu Xuwang , Qiu Jiacheng , Wang Chao , Wang Li , Feng Jianmin , Dong Lei , Long Conglai , Wang Xiaowei , Li Dejun 
Published: June 2024

AbstractCovalent triazine frameworks (CTFs) are promising battery electrodes owing to their designable functional groups, tunable pore sizes, and exceptional stability. However, their practical use is limited because of the difficulty in establishing stable ion adsorption/desorption sites. In this study, a melt‐salt‐stripping process utilizing molten trichloro iron (FeCl3) is used to delaminate the layer‐stacked structure of fluorinated covalent triazine framework (FCTF) and generate iron‐based ion storage active sites. This process increases the interlayer spacing and uniformly deposits iron‐containing materials, enhancing electron and ion transport. The resultant melt‐FeCl3‐stripped FCTF (Fe@FCTF) shows excellent performance as a potassium ion battery with a high capacity of 447 mAh g−1 at 0.1 A g−1 and 257 mAh g−1 at 1.6 A g−1 and good cycling stability. Notably, molten‐salt stripping is also effective in improving the CTF's Na+ and Li+ storage properties. A stepwise reaction mechanism of K/Na/Li chelation with C═N functional groups is proposed and verified by in situ X‐ray diffraction testing (XRD), ex‐situ X‐ray photoelectron spectroscopy (XPS), and theoretical calculations, illustrating that pyrazines and iron coordination groups play the main roles in reacting with K+/Na+/Li+ cations. These results conclude that the Fe@FCTF is a suitable anode material for potassium‐ion batteries (PIBs), sodium‐ion batteries (SIBs), and lithium‐ion batteries (LIBs).