bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dispatcher nurses’ experiences of handling drones equipped with automated external defibrillators in suspected out-of-hospital cardiac arrest - a qualitative study
Authors: Hanna Dalby-Pedersen , Erika Bergström , Ellinor Berglund , Sofia Schierbeck , Leif Svensson , Anette Nord , Jacob Hollenberg , Andreas Claesson 
Published: August 2024

Abstract
Background
Reducing the time to treatment by means of cardiopulmonary resuscitation (CPR) and defibrillation is essential to increasing survival after cardiac arrest. A novel method of dispatching drones for delivery of automated external defibrillators (AEDs) to the site of a suspected out-of-hospital cardiac arrest (OHCA) has been shown to be feasible, with the potential to shorten response times compared with the emergency medical services. However, little is known of dispatchers’ experiences of using this novel methodology.

Methods
A qualitative semi-structured interview study with a phenomenological approach was used. Ten registered nurses employed at an emergency medical dispatch centre in Gothenburg, Sweden, were interviewed and the data was analysed by qualitative content analysis. The purpose was to explore dispatcher nurses’ experiences of deliveries of AEDs by drones in cases of suspected OHCA.

Results
Three categories were formed. Nurses expressed varying compliance to the telephone-assisted protocol for dispatch of AED-equipped drones. They experienced uncertainty as to how long would be an acceptable interruption from the CPR protocol in order to retrieve a drone-delivered AED. The majority experienced that collegial support was important. Technical support, routines and training need to be improved to further optimise action in cases of drone-delivered AEDs handled by dispatcher nurses.

Conclusions
Although telephone-assisted routines for drone dispatch in cases of OHCA were available, their use was rare. Registered nurses showed variable degrees of understanding of how to comply with these protocols. Collegial and technical support was considered important, alongside routines and training, which need to be improved to further support bystander use of drone-delivered AEDs. As the possibilities of using drones to deliver AEDs in cases of OHCA are explored more extensively globally, there is a good possibility that this study could be of benefit to other nations implementing similar methods. We present concrete aspects that are important to take into consideration when implementing this kind of methodology at dispatch centres.
Prevalence of video gaming disorder in Saudi Arabia: a school-based national study
Authors: Alfaleh Amjad , Alzaher Abrar , Alkattan Abdullah , Alabdulkareem Khaled , Ibrahim Mona H. 
Published: August 2024

Abstract
Background
Video gaming is a popular leisure activity among adolescents. Those who play excessively are in danger of educational and social drawbacks and may become addicted to video gaming. Several published studies determined the prevalence of GD among children in specific Saudi regions. However, the current study assessed the national prevalence of video gaming disorder (GD) and its risk factors among school students in Saudi Arabia.

Methods
A school-based survey was conducted among adolescents in all regions of Saudi Arabia during the academic year 2021–2022. A multistage stratified cluster sampling technique was used to select the school students. An Arabic-validated version of the 9-item dichotomous (yes/no) GD Scale based on the DSM-5 criteria was used to determine GD prevalence among the students. The score ranged from zero to nine (0–9). Participants who scored five or more were deemed as having GD. Students who scored less than five were classified as normal gamers (score 0–1) or risky gamers (score 2–4).

Results
We recruited 5332 school students. Their mean age was 15.5 ± 1.7 years, and almost half of them were males (50.7%). According to the GD score, the prevalence of normal gamers was 39.08% (N = 1714), risky gamers 40.47% (N = 1775), and those with GD was, 20.45% (N = 897). Logistic regression was performed to determine the association between video gaming disorder and all the gathered variables, which include age, educational grade, sex, types of video gaming, and categories of video games played. The results showed that nationality, age, educational grade, sex, using only mobile devices to play, and playing puzzle and sports games were not associated with video gaming disorder. On the other hand, it was revealed that using tablets, game consoles, PCs; having multiple devices; and playing online, fighting, car racing, war, and adventure games were significantly linked to GD.

Conclusion
The prevalence of GD was 20.45% among Saudi school students who play video games. Utilizing more than one type of gaming device and playing games in the fighting, war, and multiplayer categories via an online connection were significantly linked to having GD. To limit video gaming addiction, we encourage screening, diagnosing, and treating disordered video gamers early. In addition, governmental authorities and video game companies should discuss and revise numerous policy measures to minimize the accessibility of video games, limit the harms and risks related to them, and assist video gamers in becoming effective members of society.
Breast Cancer Screening Interval: Effect on Rate of Late-Stage Disease at Diagnosis and Overall Survival
Authors: Zuley Margarita L. , Bandos Andriy I. , Duffy Stephen W. , Logue Durwin , Bhargava Rohit , McAuliffe Priscilla F. , Brufsky Adam M. , Nishikawa Robert M. 
Published: August 2024

PURPOSE
Controversy continues regarding the effect of screening mammography on breast cancer outcomes. We evaluated late-stage cancer rate and overall survival (OS) for different screening intervals using a real-world institutional research data mart.

METHODS
Patients having both a cancer registry record of new breast cancer diagnosis and prediagnosis screening history between 2004 and 2019 were identified from our institutional research breast data mart. Time interval between the two screening mammograms immediately preceding diagnosis and the time to cancer diagnosis were determined. Screening interval was deemed annual if ≤15 months, biennial if >15 and ≤27 months, intermittent if >27 months, and baseline if only one prediagnosis screen was known. The primary end point was late-stage cancer (TNM stage IIB or worse), and the secondary end point was OS. The association of screening interval and late-stage cancer was analyzed using multivariable logistic regression adjusting for prediagnosis characteristics. Proportional hazards regression was used for survival analysis. Potential lead time was analyzed using survival from a uniform fixed time point.

RESULTS

In total, 8,145 patients with breast cancer had prediagnosis screening mammography in the timeframe. The percentage of late-stage cancers diagnosed increased significantly with screening interval with 9%, 14%, and 19% late stages for annual, biennial, and intermittent groups (
P
< .001), respectively. The trend persisted regardless of age, race, and menopausal status. Biennial and intermittent groups had substantially worse OS than the annual screened group, with relative hazards of 1.42 (95% CI, 1.11 to 1.82) and 2.69 (95% CI, 2.11 to 3.43), respectively, and 1.39 (95% CI, 1.08 to 1.78) and 2.01 (95% CI, 1.58 to 2.55) after adjustment for potential lead time.

CONCLUSION
Annual mammographic screening was associated with lower risk of late-stage cancer and better OS across clinical and demographic subgroups. Our study suggests benefit of annual screening for women 40 years and older.
Reconstructive Endovascular Treatment of Compensative-Flow–Related Posterior Circulation Aneurysms With Anterior Circulation Artery Occlusion
Authors: Quan Tao , Zhang Xin , Li Jinyi , Wang Zhaofei , Fu Xiaojie , Feng Xin , Xu Haowen , Duan Chuanzhi , Guan Sheng 
Published: August 2024

BACKGROUND AND OBJECTIVES:
The aim of this study was to delineate the reconstructive endovascular treatment and periprocedural management of compensative-flow–related posterior circulation aneurysms with anterior circulation artery occlusion.

METHODS:
A total of 87 patients were enrolled in this retrospective double-center cohort study from May 2011 to November 2023. The baseline demographics, aneurysm characteristics, etiology and status of anterior circulation artery occlusion, treatment modalities, anesthesia management, complications, and clinical and angiographic outcomes of the patients were retrospectively analyzed in this study.

RESULTS:
Atherosclerosis and moyamoya disease were found to be the two main etiologies of anterior circulation artery occlusion. The mean American Society of Interventional and Therapeutic Neuroradiology/Society of Interventional Radiology scores were significantly higher in patients with posterior communicating artery trunk collaterals than those with posterior cerebral artery pial collaterals (P < .05). Treatment strategies included stent-assisted coiling (55, 63.2%), standard coiling (22, 25.3%), and flow diversion or flow diversion–assisted coiling (8, 9.2%). The overall rate of procedure-related ischemic and hemorrhagic complications (10.3%) was considered acceptable. The ischemic complication was significantly associated with a >20% drop in mean arterial pressure (P < .05) during the procedure. Finally, 86.2% of all patients showed a modified Rankin Scale score of 0 to 2 at the final clinical follow-up.

CONCLUSION:
Our study indicates that reconstructive endovascular treatments are feasible and effective strategies for compensative-flow–related posterior circulation aneurysms with anterior circulation artery occlusion. However, these treatments are associated with a risk of periprocedural ischemic complications, which can be reduced by collateral arterial assessment, appropriate periprocedural anesthesia management, and antiplatelet treatment.
Individual-specific associations between warble song notes and body movements in budgerigar courtship displays
Authors: Wewhare Nakul , Krishnan Anand 
Published: August 2024

ABSTRACT
Complex behavioral sequences such as courtship displays are often multimodal, and coordination between modalities is critically important. In learned and variable behavioural sequences such as songs, individual variability may also extend to multimodal coordination and the associations between modalities. However, individual variability in complex multimodal sequences and in coordination between distinct behaviours remains underexplored. Here, we report that budgerigars, which continuously learn and modify their complex warble songs, exhibit associations between body movements and song notes during courtship. Some associations are unique to individuals, and others are universal across individuals. Additionally, some individuals exhibit more unique associations than others. We also find that birds warbling in the absence of body movements emit all notes with broadly similar odds ratios. Our data suggest a hierarchy of associations, some individual-specific and others common to all individuals, between body movements and songs. We propose that these associations may be learnt and modified through social interactions, resulting in individual variability.
Germline multigene panel testing in acute and chronic pancreatitis
Authors: Ramsey Mitchell L. , Heald Brandie , Gokun Yevgeniya , Baker Josie , Groce J. Royce , Han Samuel , Hart Phil A. , Krishna Somashekar G. , Lara Luis F. , Lee Peter J. , Papachristou Georgios I. , Pearlman Rachel , Poll Sarah , Roberts Maegan E. , Stanich Peter P. 
Published: August 2024

Background/Objectives
Germline genetic testing is recommended for younger patients with idiopathic pancreatitis but there has been a lack of consensus in recommendations for those over age 35. We aimed to analyze the results of genetic testing among subjects of varying ages.

Methods
Individuals who underwent germline multigene testing for pancreatitis susceptibility genes (CASR, CFTR, CPA1, CTRC, PRSS1, SPINK1) through a large commercial laboratory between 2017 and 2022 were included. Test results and information collected from test requisition forms were evaluated. Multivariable logistic regression models were performed to identify factors associated with a positive pancreatitis panel (pathogenic, likely pathogenic, and/or increased risk variants) in pancreatitis-related genes.

Results
Overall, 2,468 subjects with primary indication of acute pancreatitis (AP) (n = 401), chronic pancreatitis (CP) (n = 631), pancreatic cancer (n = 128), or other indications (n = 1,308) completed germline testing. Among patients with AP or CP, the prevalence of any positive result for those <35 versus ≥35 years of age was 32.1% and 24.5% (p = 0.007), and the prevalence of a clinically meaningful result was 10.8% and 5.4%, respectively (p = 0.001). Positive family history of pancreatitis was associated with increased odds ratio (OR) of 8.59 (95% confidence interval (CI) 2.92–25.25) for a clinically significant panel result while each 5-year increase in age at test completion had lower odds (OR 0.89, 95% CI 0.83–0.95).

Conclusions
The highest prevalence of pathogenic variants is seen in younger individuals with a positive family history of pancreatitis. However, clinically meaningful results are identified in older subjects, suggesting that genetic counseling and testing should be considered for all age groups.
Reliably calibrating X-ray images required for preoperative planning of THA using a device-adapted magnification factor
Authors: Brüggemann Heinrich , Paulsen Aksel , Oppedal Ketil , Grasmair Markus , Hömberg Dietmar 
Published: August 2024

Background and aim
Calibrated pelvic X-ray images are needed in the preoperative planning of total hip arthroplasty (THA) to predict component sizes. Errors and mismatch in the size of one or more components are reported, which can lead to clinically relevant complications. Our aim is to investigate whether we can solve the fundamental problem of X-ray calibration and whether traditional X-ray still has a place in preoperative planning despite improved radiological alternatives.

Methods
Based on geometric and radiographic principles, we estimate that the magnification factor is adapted to the X-ray device and depends strongly on the source-image distance of the device. We analyse the errors of the various calibration methods and investigate which narrow range can be expected to show that the center of rotation is sufficiently accurate. Based on the results of several CT-scans we defined an adapted magnification factor and validated the degree of measurement accuracy.

Results
The true magnification of objects on X-ray images depends mainly on the device settings. Stem size prediction is possible to a limited extent, with an error margin of 4.3%. Components can be predicted with a safety margin of one size up and down as with CT or 3D images. The prerequisite is that the source-image distance is greater than or equal to 120 cm, the table-image distance is known, and the object-image distance is estimated according to the patient’s BMI. We defined a device-adapted magnification factor that simplifies the templating routine and can be used to obtain the most reliable preoperative dimensional measurements that can be expected from X-ray images. We found the error margin of the magnification factor with the highest degrees of prediction and precision.

Conclusion
Preoperative planning is reliable and reproducible using X-ray images if calibration is performed with the device-adapted magnification factor suggested in this paper.
Association between prediabetes and depression: A meta-analysis
Authors: Yu Yi , Wan Weitao 
Published: August 2024

Background
Previous studies evaluating the association between prediabetes and depression have shown inconsistent results. Consequently, the aim of the systematic review and meta-analysis was to investigate whether prediabetes is associated with depression in the general population.

Methods
Relevant observational studies were obtained by searching the Medline, Web of Science, and Embase databases. A random-effects model was utilized to pool the results by incorporating the influence of heterogeneity. Multiple subgroup analysis was performed to evaluate the influence of the study characteristics on the outcome.

Results
Sixteen large-scale cross-sectional studies involving 322,863 participants were included. Among the total participants, 82,154 (25.4%) had prediabetes. The pooled results showed that prediabetes was associated with a higher prevalence of depression in this population (odds ratio [OR]: 1.16, 95% confidence interval [CI]: 1.05 to 1.28, p = 0.003; I2 = 58%). Subgroup analysis showed a stronger association between prediabetes and depression in younger subjects (<50 years old, OR: 1.25, 95% CI: 1.04 to 1.50) than that in older subjects (≥50 years old, OR: 1.05, 95% CI: 1.10 to 1.10; p for subgroup difference = 0.03). Other study characteristics, such as the study country, sex of the participants, definition of prediabetes, methods for the detection of depression, and study quality score, did not seem to significantly affect the results (p for subgroup difference all > 0.05).

Conclusions
Prediabetes may be associated with a slightly higher prevalence of depression in the general population, particularly in subjects aged <50 years old.
Prevalence and associated factors of cigarette smoking and substance use among university entrance test-taking students: A GIS-based study
Authors: Mamun Mohammed A. , Roy Nitai , Gozal David , Almerab Moneerah Mohammad , Hossain Md. Shakhaoat , Al Mamun Firoj 
Published: August 2024

Background
Numerous studies have examined substance use and smoking behavior among adolescents and university students. However, little is known about these behaviors among students undergoing university entrance tests, a critical transition period from adolescence to adulthood. The entrance test can significantly affect students’ mental health, potentially leading to substance use. This study aims to investigate the prevalence of cigarette smoking and substance use among students taking these exams and the associated factors.

Methods
A cross-sectional survey was carried out on September 4th and 11th, 2022 to collect data from 1,480 university entrance test-taking students using a convenience sampling technique. Chi-square tests and logistic regression were conducted using SPSS software. Besides, GIS mapping was used to visualize the distribution of substance use and smoking behavior across districts via ArcGIS.

Results
The study found a 10% prevalence of current tobacco smoking and 4% substance use. Females (OR = 1.98; 95% CI: 1.38–2.85), urban residence (OR = 2.03; 95% CI: 1.42–2.88), repeater (OR = 1.45; 95% CI: 1.02–2.06), anxiety (OR = 1.55, 95% CI: 1.10–2.19), burnout (OR = 1.51, 95% CI: 1.00–2.12), and suicidal behavior (OR = 1.57; 95% CI: 1.03–2.40) were the significant factors for cigarette use. Whereas the urban residence (OR = 1.91; 95% CI: 1.11–3.31), anxiety (OR = 2.47, 95% CI: 1.45–4.20), and suicidal behavior (OR = 2.76; 95% CI: 1.55–4.92) significantly increased the risk of substance use. GIS analysis revealed males varied in substance use and females in tobacco smoking by district. Repeat test-takers were associated with district variations in both smoking and substance use.

Conclusions
Educational institutions, public health authorities, and policymakers must implement mental health support and substance use prevention programs for students. Integrating mental health education, providing resources, and enforcing regulations can promote healthier coping strategies and reduce substance use risks among students.
Treatment of Vedolizumab With Exclusive Enteral Nutrition in Adult Patients With Moderate to Severe Crohn's Disease (Crohn Exclusive Enteral Nutrition Study)
Authors: Wang Jing , Tang Zhishun , Li Jiao , Yin Anning , Xu Yaqing , Zou Liping , Ren Haixia , Kang Jian , Su Juan , Zhou Qian , Wang Yang , Wang Wei , Zhang Jing , Wan Huipeng , An Ping 
Published: August 2024

INTRODUCTION:
Despite increasing studies confirming the efficacy of vedolizumab (VDZ) in Crohn's disease (CD), improving the responses to this biologic agent remains challenging in clinical practice. In this article, we investigated the efficacy of combined treatment of VDZ and 16-week exclusive enteral nutrition (EEN) in moderately to severely active CD.

METHODS:
From October 2020 to October 2023, 81 patients with moderately to severely active CD treated with VDZ from 2 inflammatory bowel disease centers were retrospectively selected. Forty-one patients received treatment of VDZ with concomitant 16-week EEN (VDZ + EEN cohort), and 40 patients received VDZ treatment alone (VDZ cohort). Clinical and biological outcomes were evaluated. Endoscopic response and mucosal healing were assessed by colonoscopy at weeks 16 and 52.

RESULTS:
There was no statistically significant difference between 2 groups at baseline for demographic and clinical characteristics. Compared with patients treated with VDZ alone, patients in the VDZ + EEN cohort achieved higher rates of clinical response (84.2% vs 40.0%), clinical remission (81.6% vs 30.0%), endoscopic response (91.4% vs 34.6%), including mucosal healing (85.7% vs 26.9%) at week 16. The superiority of VDZ + EEN treatment sustained in maintenance, with 76.7% (vs 33.3%) clinical response, 70.0% (vs 26.7%) clinical remission, 76.9% (vs 33.3%) endoscopic response, and 61.5% (vs 26.7%) mucosal healing at week 52. None of the patients experienced severe adverse events.

DISCUSSION:
VDZ with concomitant 16-week EEN might be an effective and optimized approach with solid efficacy in the induction and maintenance treatment of active CD.
Evaluation of upper airway ultrasonographic measurements in predicting difficult intubation: A cross-section of the Turkish population
Authors: Sayir Tugba Nur , Tuncer Bilge , Erkilic Ezgi 
Published: August 2024

Abstract

Objectives
Studies have shown that there are differences in clinical evaluation parameters and difficult intubation rates among different ethnic populations. In our study, we aimed to evaluate the efficacy of upper airway clinical and ultrasonographic measurement methods in Turkish population.

Methods
Our study is a single-center, prospective, observational study conducted with 402 patients. All patients underwent clinical airway measurements which are routinely used in pre-anesthetic evaluation. In addition, ultrasonographic anterior neck soft tissue thickness measurements of each patient were made and recorded.

Results
Among the clinical measurements, we found the neck circumference/thyromental distance (TMD) ratio to be significant with a cut-off value of 5.5 and a sensitivity of 92.9% and a specificity of 88.3%, while among the ultrasonographic anterior neck measurements, we found the skin–epiglottic distance to be the most sensitive measurement. We found that there was a positive relationship between the neck circumference/TMD ratio and skin–epiglottis.

Conclusions
In our study, we found that routine measurement methods used in airway examination alone are not sufficient, and measurements that take into account the body proportions of the patients, such as the neck circumference/TMD ratio and the ultrasonographic evaluations are more useful in predicting difficult intubation.
Crystal structure of poly[bis(μ3-3-fluoro-4-(1H-1,2,4-triazol-1-yl)benzoato-κ3
O:O′:N)cadmium(II)] – dimethylformamide (1/1), C21H17CdF2N7O5
Authors: Wang Yanqing , Hao Yifan , Wang Zhangjing , Lv Xiaoxu , Gu Fangjing , Chen Jiaxiang , Dong Lintao 
Published: August 2024

Abstract
C21H17CdF2N7O5, monoclinic, C2/c (no. 15), a = 15.2452(2) Å, b = 16.1445(2) Å, c = 9.58901(14) Å, β = 101.0960(15)°, V = 2315.99(6) Å3, Z = 4, Rgt
(F) = 0.0281, wRref
(F
2) = 0.0777, T = 273 K.