bluuebunny/crossref_metadata_2025_split huggingface dataset:
Changes in biotic and habitat indices in response to dam removals in Ohio
Authors: Krieger Kenneth A. , Zawiski Bill 
Published: July 2013

Abstract
Dams on rivers modify habitat and water chemistry, resulting in degradation of fish and macroinvertebrate community integrity within and, in some cases, downstream of the dam pools. Thus, removal of a dam is usually accompanied by the expectation of improved habitat quality and biotic integrity. The Ohio Environmental Protection Agency applies a Qualitative Habitat Evaluation Index, an Index of Biotic Integrity (IBI, fishes), and an Invertebrate Community Index (ICI) to assess stream habitat quality and the habitat-dependent structural and functional integrity of the fish and invertebrate communities. Our objective was to demonstrate that these three indices reliably detect differences in the quality of habitat and fish and macroinvertebrate communities between dam pools and free-flowing reaches and that they are sensitive to changes in habitat and biotic condition following dam removal. Data from 21 stream reaches in Ohio containing dams showed that habitat and biota in dam pools possess lower quality than nearby upstream and downstream reaches. Case studies of dam removals on the Cuyahoga, Olentangy, and Sandusky Rivers confirmed that the indices are sensitive to the rapid changes in habitat and biotic communities that accompany return of dam pools to free-flowing conditions. IBI and ICI scores indicated that the former dam pools had met or exceeded the designated aquatic life use criteria within 1 yr following dam removal. We conclude that the IBI and ICI are valuable tools for measuring the rapidity and extent of changes in the fish and macroinvertebrate communities, respectively, following dam removal.
Assessing stream restoration potential of recreational enhancements on an urban stream, Springfield, Ohio
Authors: Ritter John , Shaw Kelly , Evelsizor Aaron , Minter Katherine , Rigsby Chad , Shearer Kristen 
Published: July 2013

Abstract
The stream restoration potential of recreational modifications made to lowhead dams on an urban reach of Buck Creek, in Springfield, Ohio, is dependent on constraints imposed by the urban infrastructure on stream grade. A privately led initiative to improve the recreational potential of a 9 km reach of Buck Creek and its tributary Beaver Creek includes the modification of four lowhead dams. The hydraulic heights of these dams will be replaced with a series of v-shaped drop structures engineered to create hydraulics conducive to kayak play. The drop structure is a constructed channel constriction composed of a hard step in the long stream profile immediately upstream of a scour pool, forming a morphologic sequence of constriction, step, and pool. In this study, we assess the potential benefits of these changes for urban stream restoration. Two of the dams have been modified to date. Stream quality, as measured by the qualitative habitat evaluation index (QHEI), dissolved oxygen of surface and substrate water, and the pollution tolerance index (PTI), increased at the Snyder Park site but decreased at the Art Museum site. Stream quality increased at the Snyder Park site, where stream grade could be lowered upstream of the lowhead dam, but decreased at the Art Museum site, where grade upstream of the lowhead dam had to be maintained because of water and wastewater utilities buried in the channel bed. Where stream grade is lowered in the former impoundment, sand and gravel deposits upstream of the constriction are not embedded with finer particles and organic matter. Increased QHEI values, particularly the substrate metric, and greater abundance and diversity of pollution-intolerant macroinvertebrates, supported by higher dissolved oxygen in the substrate water, characterize the Snyder Park site. At the Art Museum site, the v-shaped constriction increased the upstream impounded area. The substrate has become embedded with fine sands, silts, and organics, lowering QHEI values, dissolved oxygen is critically low in the substrate, and macroinvertebrate populations are more pollution-tolerant. The results highlight the significance of stream grade if stream restoration is to be incorporated into the engineering design of in-stream recreational features.
Land Subsidence Due to Withdrawal of Fluids
Authors: Poland J. F. , Davis G. H. 
Published: July 2013

Abstract
Land-surface subsidence due to the withdrawal of fluids by man has become relatively common in the United States since 1940 and has been described at several other places throughout the world. This paper reviews the known examples of appreciable land subsidence caused by fluid withdrawal. Those related to exploitation of oil and gas fields include Goose Creek, Texas; Wilmington, California; Lake Maracaibo, Venezuela; Niigata, Japan; and the Po Delta in Italy. The areas of major subsidence related to ground-water withdrawal include areas in Japan; Mexico City, Mexico; and Texas, Arizona, Nevada, and California. The areas of greatest extent and maximum subsidence are in California.
The principles involved in the compaction of sediments and of aquifer systems, basically the increase in effective stress, are examined briefly, together with their application to subsidence problems involving head decline both under water table and confined conditions. The amount of compaction that a confined aquifer system will experience is a function of compressibility. Other factors that influence compaction (and, in part, compressibility) include particle size and shape, clay mineralogy, geochemistry of pore water in the clayey beds and of the water in contiguous aquifers, and secondary compression.
Land subsidence has caused great damage in some areas. At several of these places, subsidence problems are being alleviated in one or more of several ways; these include (1) cessation of withdrawal and (2) increase or restoration of reservoir pressure by reduction in production rate, artificial recharge, or repressuring by injection of water. The greatest subsidence control measures are being taken at Wilmington, California, where subsidence that had reached 27 feet at the center now is nearly stopped; in addition, significant rebound has occurred.
A nested case–control analysis of self-reported physical functioning after total knee replacement surgery in the 45 and Up Study Cohort
Authors: Rogers Kris D , Blyth Fiona M , March Lyn M , Jorm Louisa 
Published: July 2013

ObjectivesThe rate of total knee arthroplasty surgery (TKA) is rising in Australia despite varying impacts of TKA on physical function (PF) in population-based studies. There are potentially modifiable risk factors that could enhance PF after TKA, so we evaluated (1) the levels of PF in persons with TKA and the rest of the population, (2) potentially modifiable characteristics of those reporting poor PF after TKA.DesignNested case–control study.SettingPopulation-based cohort study in New South Wales, Australia.ParticipantsMembers of a large (n=267 151) cohort study recruited by a self-completed, mailed questionnaire from 2006 to 2008. After exclusions (for hip arthroplasty, partial TKA, missing important variables and mismatching TKA status between self-reported and hospital record data), this study included 205 148 participants.Primary and secondary outcomesPrimary outcome, Medical Outcomes Study Physical Function scale (MOS-PF). Secondary outcome, dispensings of analgesics or anti-inflammatory drugs.ResultsWe found 2916 TKA participants and 202 232 participants with no TKA (confirmed across datasets). Persons with TKA had a lower MOS-PF (59.9, 95% CI 58.5 to 60.6) than those without TKA (83.8, 95% CI 83.7 to 83.9). In the matched analysis, the TKA group had a lower MOS-PF (59.9, 95% CI 59.9 to 62.4) than those without TKA (68.4, 95% CI 67.8 to 69.0). In persons with TKA, lower levels of MOS-PF were associated with low self-rated health, high psychological distress, comorbidity, greater age, recent treatment for osteoarthritis and use of paracetamol. Women had an MOS-PF that was 11.6 points (95% CI 9.5 to 13.8) lower than men.ConclusionsSeveral modifiable risk factors have been identified to influence PF in persons receiving TKA, with notable differences between sexes. The importance of these risk factors should be examined in incident TKA to test if early identification and intervention for individuals can improve outcomes.
Participation in Cardiac Rehabilitation and Survival After Coronary Artery Bypass Graft Surgery
Authors: Pack Quinn R. , Goel Kashish , Lahr Brian D. , Greason Kevin L. , Squires Ray W. , Lopez-Jimenez Francisco , Zhang Zixin , Thomas Randal J. 
Published: July 2013

Background—
Cardiac rehabilitation (CR) is recommended for all patients after coronary artery bypass surgery, yet little is known about the long-term mortality effects of CR in this population.

Methods and Results—

We performed a community-based analysis on residents of Olmsted County, Minnesota, who underwent coronary artery bypass surgery between 1996 and 2007. We assessed the association between subsequent outpatient CR attendance and long-term survival. Propensity analysis was performed. Cox proportional hazards regression was then used to assess the association between CR attendance and all-cause mortality adjusted for the propensity to attend CR. We identified 846 eligible patients (age 66±11 years, 76% men, and 96% non-Hispanic whites) who survived at least 6 months after surgery, of whom 582 (69%) attended CR. During a mean (±SD) follow-up of 9.0±3.7 years, the 10-year all-cause Kaplan-Meier mortality rate was 28% (193 deaths). Adjusted for the propensity to attend CR, participation in CR was associated with a 10-year relative risk reduction in all-cause mortality of 46% (hazard ratio, 0.54; 95% confidence interval, 0.40–0.74;
P
<0.001) and a 10-year absolute risk reduction of 12.7% (number needed to treat=8). There was no evidence of a differential effect of CR on mortality with respect to age (≥65 versus <65 years), sex, diabetes, or prior myocardial infarction.

Conclusions—
CR attendance is associated with a significant reduction in 10-year all-cause mortality after coronary artery bypass surgery. Our results strongly support national standards that recommend CR for this patient group.
Regional-Scale Rainy Season Onset Detection: A New Approach Based on Multivariate Analysis
Authors: Boyard-Micheau Joseph , Camberlin Pierre , Philippon Nathalie , Moron Vincent 
Published: July 2013

AbstractIn agroclimatology, the rainy season onset and cessation dates are often defined from a combination of several empirical rainfall thresholds. For example, the onset may be the first wet day of N consecutive days receiving at least P millimeters without a dry spell lasting n days and receiving less than p millimeters in the following C days. These thresholds are parameterized empirically in order to fit the requirements of a given crop and to account for local-scale climatic conditions. Such local-scale agroclimatic definition is rigid because each threshold may not be necessarily transposable to other crops and other climate environments. A new approach is developed to define onset/cessation dates and monitor their interannual variability at the regional scale. This new approach is less sensitive to parameterization and local-scale contingencies but still has some significance at the local scale. The approach considers multiple combinations of rainfall thresholds in a principal component analysis so that a robust signal across space and parameters is extracted. The regional-scale onset/cessation date is unequally influenced by input rainfall parameters used for the definition of the local rainy season onset. It appears that P is a crucial parameter to define onset, C plays a significant role at most stations, and N seems to be of marginal influence.
Assessment of High-Resolution Satellite-Based Rainfall Estimates over the Mediterranean during Heavy Precipitation Events
Authors: Stampoulis Dimitrios , Anagnostou Emmanouil N. , Nikolopoulos Efthymios I. 
Published: July 2013

Abstract
Heavy precipitation events (HPE) can incur significant economic losses as well as losses of lives through catastrophic floods. Evidence of increasing heavy precipitation at continental and global scales clearly emphasizes the need to accurately quantify these phenomena. The current study focuses on the error analysis of two of the main quasi-global, high-resolution satellite products [Climate Prediction Center (CPC) morphing technique (CMORPH) and Precipitation Estimation from Remotely Sensed Imagery Using Artificial Neural Networks (PERSIANN)], using rainfall data derived from high-quality weather radar rainfall estimates as a reference. This analysis is based on seven major flood-inducing HPEs that developed over complex terrain areas in northern Italy (Fella and Sessia regions) and southern France (Cevennes–Vivarais region). The storm cases were categorized as convective or stratiform based on their characteristics, including rainfall intensity, duration, and area coverage. The results indicate that precipitation type has an effect on the algorithm's ability to capture rainfall effectively. Convective storm cases exhibited greater rain rate retrieval errors, while low rain rates in stratiform-type systems are not well captured by the satellite algorithms investigated in this study, thus leading to greater missed rainfall volumes. Overall, CMORPH exhibited better error statistics than PERSIANN for the HPEs of this study. Similarities are also shown in the two satellite products' error characteristics for the HPEs that occurred in the same geographical area.
An Analysis of the Use of the Kellgren and Lawrence Grading System to Evaluate Peritalar Arthritis Following Total Ankle Arthroplasty
Authors: Mayich D. Joshua , Pinsker Ellie , Mayich Michael S. , Mak Walter , Daniels Timothy R. 
Published: July 2013

Background: The Kellgren and Lawrence grading system (KLGS) has been used throughout the literature for the radiographic staging of osteoarthritis (OA) of the peritalar joints. Despite its widespread use, the KLGS has never been validated for use in this clinical circumstance. The purpose of this study was to determine the inter- and intrarater reliability of the KLGS in the assessment of radiographic progression of OA in the peritalar joints following total ankle replacement (TAR). Methods: One hundred twenty pre- and minimum 5-year postoperative weight-bearing lateral radiographs following 60 consecutive cases of TAR were utilized. Each individual film was considered separately for the purposes of this study. Of those films, 93 and 98 were found to have adequate visualization of the subtalar (STJ) and talonavicular (TNJ) joints, respectively. Three qualified reviewers graded the films according to the KLGS on 2 separate occasions, with 1 month separating the 2 readings. The results were analyzed for intra- and interobserver reliability. The degree of agreement was analyzed using the weighted kappa (κw) statistic, Fleiss’s kappa (Fleiss’s κ), and percentage agreement Results: Interrater agreements were moderate (κw = 0.37 ± 0.06; Fleiss’s κ = 0.21 ± 0.03) for the STJ to fair (κw = 0.43 ± 0.06; Fleiss’s κ = 0.25 ± 0.03) for the TNJ. Intrarater agreements for the STJ were moderate (mean κw = 0.43 ± 0.07) and moderate for the TNJ as well (mean κw = 0.46 ± 0.07). The reliability of the KLGS, although not originally designed for use in the setting of inflammatory arthropathy, was not notably affected when being used to grade inflammatory versus noninflammatory arthropathy. Conclusions: The KLGS is likely not a reliable tool for grading the degree of OA present in the peritalar joints prior to treatment and following TAR for research purposes. Using the KLGS in the setting of inflammatory arthritis versus OA did not produce any notable differences in the observed reliability. It is important to remember this has not been assessed in the clinical environment. Further work is required to determine the optimal method for assessment of peritalar OA. Level of Evidence: Level II, prospective comparative study.
Comprehensive analysis of microRNA profiles in multiple sclerosis including next-generation sequencing
Authors: Keller Andreas , Leidinger Petra , Steinmeyer Florian , Stähler Cord , Franke Andre , Hemmrich-Stanisak Georg , Kappel Andreas , Wright Ian , Dörr Jan , Paul Friedemann , Diem Ricarda , Tocariu-Krick Beatrice , Meder Benjamin , Backes Christina , Meese Eckart , Ruprecht Klemens 
Published: July 2013

Background: MicroRNAs (miRNAs) are short, noncoding RNAs with gene regulatory functions whose expression profiles may serve as disease biomarkers. Objective: The objective of this study was to perform a comprehensive analysis of miRNA expression profiles in blood of patients with a clinically isolated syndrome (CIS) or relapsing–remitting multiple sclerosis (RRMS) including next-generation sequencing (NGS). Methods: miRNA expression was analyzed in whole blood samples from treatment-naïve patients with CIS ( n = 25) or RRMS ( n = 25) and 50 healthy controls by NGS, microarray analysis, and quantitative real-time polymerase chain reaction (qRT-PCR). Results: In patients with CIS/RRMS, NGS and microarray analysis identified 38 and eight significantly deregulated miRNAs, respectively. Three of these miRNAs were found to be significantly up- (hsa-miR-16-2-3p) or downregulated (hsa-miR-20a-5p, hsa-miR-7-1-3p) by both methods. Another five of the miRNAs significantly deregulated in the NGS screen showed the same direction of regulation in the microarray analysis. qRT-PCR confirmed the direction of regulation for all eight and was significant for three miRNAs. Conclusions: This study identifies a set of miRNAs deregulated in CIS/RRMS and reconfirms the previously reported underexpression of hsa-miR-20a-5p in MS. hsa-miR-20a-5p and the other validated miRNAs may represent promising candidates for future evaluation as biomarkers for MS and could be of relevance in the pathophysiology of this disease.
Conditional ablation of LYVE-1+ cells unveils defensive roles of lymphatic vessels in intestine and lymph nodes
Authors: Jang Jeon Yeob , Koh Young Jun , Lee Seung-Hun , Lee Junyeop , Kim Kyoo Hyun , Kim Daesoo , Koh Gou Young , Yoo Ook Joon 
Published: July 2013

Key Points
Intact lymphatic vessels are required for structural and functional maintenance of surrounding tissues in the intestine and lymph nodes.
Revised response criteria for myelofibrosis: International Working Group-Myeloproliferative Neoplasms Research and Treatment (IWG-MRT) and European LeukemiaNet (ELN) consensus report
Authors: Tefferi Ayalew , Cervantes Francisco , Mesa Ruben , Passamonti Francesco , Verstovsek Srdan , Vannucchi Alessandro M. , Gotlib Jason , Dupriez Brigitte , Pardanani Animesh , Harrison Claire , Hoffman Ronald , Gisslinger Heinz , Kröger Nicolaus , Thiele Juergen , Barbui Tiziano , Barosi Giovanni 
Published: July 2013

Key Points
Treatment response criteria for MF must capture drug benefit in terms of symptom burden. The current document includes stricter definitions of red cell transfusion need and independence.
Loss of CARM1 is linked to reduced HuR function in replicative senescence
Authors: Pang Lijun , Tian Haiyan , Chang Na , Yi Jie , Xue Lixiang , Jiang Bin , Gorospe Myriam , Zhang Xiaowei , Wang Wengong 
Published: July 2013

Abstract

Background
The co-activator-associated arginine methyltransferase 1 (CARM1) catalyzes the methylation of HuR. However, the functional impact of this modification is not fully understood. Here, we investigated the influence of HuR methylation by CARM1 upon the turnover of HuR target mRNAs encoding senescence-regulatory proteins.

Results
Changing the methylation status of HuR in HeLa cells by either silencing CARM1 or mutating the major methylation site (R217K) greatly diminished the effect of HuR in regulating the turnover of mRNAs encoding cyclin A, cyclin B1, c-fos, SIRT1, and p16. Although knockdown of CARM1 or HuR individually influenced the expression of cyclin A, cyclin B1, c-fos, SIRT1, and p16, joint knockdown of both CARM1 and HuR did not show further effect. Methylation by CARM1 enhanced the association of HuR with the 3′UTR of p16 mRNA, but not with the 3′UTR of cyclin A, cyclin B1, c-fos, or SIRT1 mRNAs. In senescent human diploid fibroblasts (HDFs), reduced CARM1 was accompanied by reduced HuR methylation. In addition, knockdown of CARM1 or mutation of the major methylation site of HuR in HDF markedly impaired the ability of HuR to regulate the expression of cyclin A, cyclin B1, c-fos, SIRT1, and p16 as well to maintain a proliferative phenotype.

Conclusion
CARM1 represses replicative senescence by methylating HuR and thereby enhancing HuR’s ability to regulate the turnover of cyclin A, cyclin B1, c-fos, SIRT1, and p16 mRNAs.
Furosemide-induced severe hypokalemia with rhabdomyolysis without cardiac arrest
Authors: Ruisz Wolfgang , Stöllberger Claudia , Finsterer Josef , Weidinger Franz 
Published: July 2013

Abstract

Background
Hypokalemia induced by diuretic abuse is a life-threatening emergency.

Case presentation
A 22-years-old female nurse with a body mass index 18 suffered from myalgias, vomiting and diarrhea. Blood tests revealed hypokalemia with a lowest value of 1.1 mmol/l, moderate hyponatremia, metabolic alkalosis, mild renal insufficiency and creatinphosphokinase-elevation. Since hypokalemia and alkalosis were unexplained, she was asked for diuretic-intake. She confessed that she has taken 250 mg furosemide/day for the last 4 months to improve the shape of her muscles. Furosemide tablets were given to her by a physician attending the gym where she exercised. After electrolyte substitution, laboratory abnormalities regressed and no cardiac arrests were observed. Psychiatric investigation diagnosed an adjustment disorder.

Conclusion
Furosemide abuse has to be considered even in underweight individuals, especially if they have a psychiatric instability or work in health care institutions.
A modular framework for implementing joint wireless network coding and scheduling algorithms
Authors: Broustis Ioannis , Paschos Georgios S , Syrivelis Dimitris , Georgiadis Leonidas , Tassiulas Leandros 
Published: July 2013

Abstract
Intersession network coding (NC) can provide significant performance benefits via mixing packets at wireless routers; these benefits are especially pronounced when NC is applied in conjunction with intelligent scheduling. NC, however, imposes certain processing operations, such as encoding, decoding, copying, and storage. When not utilized carefully, all these operations can induce tremendous processing overheads in practical settings. Our testbed measurements suggest that such processing operations can severely degrade the router throughput, especially at high bit rates. Motivated by this, we design network coding framework for rate adaptive wireless links (NCRAWL). The design of NCRAWL facilitates low overhead NC operations, thereby effectively approaching the theoretically expected throughput benefits of joint NC and scheduling. We implement and evaluate NCRAWL on a wireless testbed. Our experiments demonstrate that NCRAWL meets the theoretical predicted throughput gain while requiring much less CPU processing, compared to related frameworks.