bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Practical, Modular, and General Synthesis of 3‐Coumaranones Through Gold‐Catalyzed Intermolecular Alkyne Oxidation Strategy.
Authors: Shu Chao , Liu Rongfu , Liu Shuang , Li Jian‐Qiao , Yu Yong‐Fei , He Qiao , Lu Xin , Ye Long‐Wu 
Published: November 2015

AbstractThe Au‐catalyzed intramolecular alkyne oxidation of 2‐ethynylanisoles (I) using quinoline N‐oxides as oxidants affords title compounds (II) in moderate to good yields.
ChemInform Abstract: Domino One‐Pot Process for the Synthesis of Isobenzofuran‐1(3H)‐ones via [Cu]‐Catalysis Using Water as the Green Solvent.
Authors: Mahendar Lodi , Satyanarayana Gedu 
Published: November 2015

AbstractThe title benzofurans are efficiently obtained by a one‐pot CuI‐catalyzed domino intermolecular cyanation‐oxacyclization‐hydrolysis sequence under environmentally benign reaction conditions.
ChemInform Abstract: Enantioselective Borylative Dearomatization of Indoles Through Copper(I) Catalysis.
Authors: Kubota Koji , Hayama Keiichi , Iwamoto Hiroaki , Ito Hajime 
Published: November 2015

AbstractThe use of a chiral bisphosphine‐copper(I) complex as catalyst allows for the regio‐ and enantioselective addition of an active borylcopper(I) species to indole‐2‐carbaldehydes followed by diastereoselective protonation to give indoline derivatives.
ChemInform Abstract: A One‐Pot, Three‐Component and Solvent‐Free Synthesis of 2,3‐Disubstituted Isoindolin‐1‐ones.
Authors: Adib Mehdi , Peytam Fariba , Zainali Mohsen , Zhu Long‐Guan , Wu Jing 
Published: November 2015

AbstractSimply heating a mixture of β‐dicarbonyl compounds, benzylamines, and acid (II) under solvent‐free conditions gives isoindolines in good to excellent yields.
ChemInform Abstract: [3 + 2] Annulations Between Indoles and α,β‐Unsaturated Ketones: Access to Pyrrolo[1,2‐a]indoles and Model Reactions Toward the Originally Assigned Structure of Yuremamine.
Authors: Li Haokun , Wang Zhonglei , Zu Liansuo 
Published: November 2015

AbstractThe highly functionalized title indoles are rapidly obtained in a single step.
ChemInform Abstract: Synthesis of Cyclic Carbonates Catalyzed by Aluminum Heteroscorpionate Complexes.
Authors: Martinez Javier , Castro‐Osma Jose A. , Earlam Amy , Alonso‐Moreno Carlos , Otero Antonio , Lara‐Sanchez Agustin , North Michael , Rodriguez‐Dieguez Antonio 
Published: November 2015

AbstractA newly developed aluminum heteroscorpionate complex is used for transformation reactions of various substituted epoxides into the corresponding carbonates.
ChemInform Abstract: Practical Synthesis of Polysubstituted Haloimidazoles from 1,1‐Dibromoalkenes and Amidines.
Authors: Li Yibiao , Cheng Liang , Shao Yan , Jiang Shaohua , Cai Jialing , Qing Ning 
Published: November 2015

AbstractBromoalkynes, generated in situ from 1,1‐dibromoalkenes, undergo copper‐catalyzed cycloamination reactions with amidines or pyridin‐2‐amine to give highly functionalized bromoimidazoles.
ChemInform Abstract: Convenient One‐Pot Synthesis of Monofluorinated Functionalized 4H‐Pyran Derivatives via Multi‐Component Reactions.
Authors: Xu Xiaoling , Shi Wei , Zhou Yu , Wang Yang , Zhang Min , Song Liping , Deng Hongmei 
Published: November 2015

AbstractThe multicomponent reaction of ethyl 2‐fluoroacetoacetate, malononitrile, aromatic aldehydes, and ethanol affords monofluorinated functionalized 4H‐pyran derivatives of type (V).
ChemInform Abstract: The N,N′‐Dioxide/Ni(II)‐Catalyzed Asymmetric Inverse‐Electron‐Demand Hetero‐Diels—Alder Reaction of Methyleneindolinones with Hetero‐Substituted Alkenes.
Authors: Zhou Yuhang , Lin Lili , Yin Chengkai , Wang Zhengmeng , Liu Xiaohua , Feng Xiaoming 
Published: November 2015

AbstractThe scalable title reaction of various methyleneindolinones with mono‐ and 1,1‐disubstituted acyclic vinyl ethers, ethylvinyl sulfide (X) and dihydropyran (XII) delivers the corresponding products in high yield, with high to excellent diastereomeric excess and with excellent enantioselectivity.
ChemInform Abstract: Highly Enantioselective Nucleophilic Dearomatization of Pyridines by Anion‐Binding Catalysis.
Authors: Garcia Mancheno Olga , Asmus Soeren , Zurro Mercedes , Fischer Theresa 
Published: November 2015

AbstractThe one‐pot dearomatization of pyridines involves the in situ formation of N‐Troc pyridinium chloride salts followed by nucleophilic addition of ketene acetal (III) in the presence of chiral hydrogen donor catalyst (CTR).
ChemInform Abstract: Thermal Reactions Involving 1‐Azadienes and Allenic Esters‐(II): Reactions of 3‐(N‐Aryliminomethyl)chromones with Allenic Esters—Tandem Reorganization of [2 + 2] Cycloadducts to Novel Compounds.
Authors: Kapur Ashish , Sharma Vishal , Kaur Amandeep , Parashar Poonam , Kanwal Priyanka , Gupta Vivek , Ishar Mohan Paul S. 
Published: November 2015

AbstractThe course of the title reaction depends on the substituents on the allenic esters providing three different types of aromatic ketones.
ChemInform Abstract: Microwave‐Assisted Synthesis of 2‐Pyridinylethyl Indazoles.
Authors: Ge Dao‐Liang , Zhang Xiao‐Zhuan , Chen Shan‐Yong , Pu Lin , Yu Xiao‐Qi 
Published: November 2015

AbstractThe transition‐metal free hydroamination reaction of 2‐vinylpyridine with indazoles affords N1 and N2 alkylated indazoles, whereas 4‐vinylpyridine gives N1‐alkylated products exclusively.
ChemInform Abstract: Asymmetric Synthesis of δ‐Chloro‐β‐amino‐N‐sulfinyl Imidates as Versatile Chiral Building Blocks for the Synthesis of 2,3‐Disubstituted Piperidines.
Authors: Semina Elena , Colpaert Filip , Van Hecke Kristof , De Kimpe Norbert , Mangelinckx Sven 
Published: November 2015

AbstractNew β‐amino‐δ‐chloro carboximidates bearing a chiral sulfoxide auxiliary are prepared and used as building blocks for the synthesis of enantio‐ and diastereomeric pure 2,3‐disubstituted piperidines (similar reactions based on the minor diastereomer are not shown).
ChemInform Abstract: The Regioselective Homocoupling of meta‐Hydroxypyridines with Hypervalent Iodine(III).
Authors: Yang Ping Syun , Tsai Mi Ting , Tsai Meng Han , Ong Chi Wi 
Published: November 2015

AbstractVarious dihydroxy‐bipyridines are highly regioselectively obtained by exclusive ortho‐coupling with respect to the hydroxy group at the pyridine ring and without any prefunctionalization of the pyridine under metal‐free reaction conditions.
ChemInform Abstract: Novel Ionic Liquid [2‐Eim] HSO4 as a Dual Catalytic‐Solvent System for Preparation of Hexahydroquinolines under Green Conditions.
Authors: Ghorbani M. , Noura S. , Oftadeh M. , Gholami E. , Zolfigol M. A. 
Published: November 2015

AbstractThe novel Broensted acidic ionic liquid exhibits excellent catalytic activity in the one‐pot multi‐component reaction between various aromatic aldehydes, dimedone, ethyl acetoacetate, and ammonium acetate affording the title quinolines.
ChemInform Abstract: One‐Pot Organocatalytic Enantioselective Michael Addition and Aza‐Cyclization/Dehydration Cascade Reaction Strategy: Asymmetric Synthesis of Highly Functionalized 1,4‐Dihydroquinolines.
Authors: Kim Hanna , Kim Sung‐Gon 
Published: November 2015

AbstractThe title cascade reaction allows the synthesis of 1,4‐dihydroquinoline with high enantioselectivities up to 92% from nitrostyrenes (I) and various β‐ketoesters.
ChemInform Abstract: Tandem Cross Enyne Metathesis (CEYM)—Intramolecular Diels—Alder Reaction (IMDAR). An Easy Entry to Linear Bicyclic Scaffolds.
Authors: Miro Javier , Sanchez‐Rosello Maria , Sanz Alvaro , Rabasa Fernando , del Pozo Carlos , Fustero Santos 
Published: November 2015

AbstractStarting from non‐substituted olefin moieties, the linear bicyclic derivatives are obtained as a single diastereomer.
ChemInform Abstract: Hydrazones as Productive Dienophiles in the Inverse Electron Demand Diels—Alder Reactions of 1,3,5‐Triazines.
Authors: Yang Kai , Yang Zhen , Dang Qun , Bai Xu 
Published: November 2015

AbstractThe title reaction allows the synthesis of a wide range of highly functionalized pyrimidine derivatives in moderate to good yields.
ChemInform Abstract: Model Studies on Peroxidic Glutathione Transferase (GST) Inhibitors: C5‐Methylated 1,2,4‐Trioxanes with C6‐Acrylate Side Chains.
Authors: Griesbeck Axel G. , Maassen Andreas , Braeutigam Maria , Pietsch Markus 
Published: November 2015

AbstractThe diastereoselective porphyrin‐sensitized singlet oxygen ene reaction of allylic alcohol (I) gives the key precursor (II), which can be easily converted into the title trioxane derivatives.
ChemInform Abstract: Two New Eudesmanolides from the Flowers of Achillea millefolium.
Authors: Zhang Chun‐Bao , Ni Zhi‐Yu , Wang Jin , Qing Xia , Yan Hui‐Min , Shi Qing‐Wen , Sauriol Francoise , Gu Yu‐Cheng , Wu Yi‐Bing 
Published: November 2015

Abstractisolation and structure elucidation
ChemInform Abstract: Two New Sesquiterpenes from the Resin of Toxicodendron vernicifluum.
Authors: He Jiang‐Bo , Lu Qing , Cheng Yong‐Xian 
Published: November 2015

AbstractTwo new sesquiterpenes, toxicodenane D (I) and toxicodenane E (II), are isolated together with six known sesquiterpenoids.
ChemInform Abstract: An Analysis of the Complementary Stereoselective Alkylations of Imidazolidinone Derivatives Toward α‐Quaternary Proline‐Based Amino Amides.
Authors: Knight Brian J. , Stache Erin E. , Ferreira Eric M. 
Published: November 2015

AbstractThe alkylation of proline‐type imidazolidinones (I) and (V) derived from isobutyraldehyde or 1‐naphthaldehyde gives stereodivergent products, which can be readily cleaved to afford both α‐alkylated proline enantiomers.
ChemInform Abstract: Two 2,6‐Dioxabicyclo[3.3.1]nonan‐3‐ones from Phragmanthera capitata (Spreng.) Balle (Loranthaceae).
Authors: Lenta Bruno N. , et al.  
Published: November 2015

AbstractTwo new natural lactones (I) are isolated along with eight known compounds from the leaves of Phragmanthera capitata and screened for their in vitro antiplasmodial activity against the Plasmodium falciparum cloroquine sensitive strains NF54 and 3D7.
ChemInform Abstract: A New Tricyclic Alkaloid from Portulaca oleracea L.
Authors: Yue Su , Jiao Ze‐Zhao , Sun Hong‐Xiang , Jin Tian‐Yun , Xiang Lan 
Published: November 2015

AbstractThe new tricyclic alkaloid (I), portulacatone, is isolated together with eight known compounds from the title species.
ChemInform Abstract: Spin Transfer Torque Switching and Perpendicular Magnetic Anisotropy in Full Heusler Alloy CO2FeAl‐Based Tunnel Junctions
Authors: Sukegawa H. , Wen Z. C. , Kasai S. , Inomata K. , Mitani S. 
Published: November 2015

AbstractReview: 57 refs.
ChemInform Abstract: Functional Metal‐organic Frameworks: “The Other FMOFs”/FMOFs 2.0
Authors: Omary Mohammad A. , Kaipa Ushasree , Tekarli Sammer M. , Arvapally Ravi K. , Ivy Joshua F. , Horn Laura C. , Yang Chi 
Published: November 2015

AbstractReview: recent advances of fluorous metal‐organic frameworks as porous solids and lighemitting properties; 10 refs.
ChemInform Abstract: 4′‐Selenonucleosides as Next‐Generation Nucleosides
Authors: Sahu Pramod K. , Naik Siddhi D. , Yu Jinha , Jeong Lak Shin 
Published: November 2015

AbstractReview: stereoselective synthesis, conformation analysis, and biological activity of various modified 4′‐selenonucleosides; 20 refs.
ChemInform Abstract: Circularly Polarized Luminescence from Simple Organic Molecules
Authors: Sanchez‐Carnerero Esther M. , Agarrabeitia Antonia R. , Moreno Florencio , Maroto Beatriz L. , Muller Gilles , Ortiz Maria J. , de la Moya Santiago 
Published: November 2015

AbstractReview: [highlights and difficulty in developing chiral simple organic molecules able to emit left‐ or right‐circularly polarized light; 48 refs.
Zerkleinerung von polymeren Ionenaustauscherpartikeln durch Feinstmahlung
Authors: Schäfer Maria , Peuker Urs 
Published: November 2015

AbstractSubmikrone Ionenaustauscherpartikel werden unter anderem zur Verarbeitung in Polymerkompositpartikeln genutzt. In der vorliegenden Arbeit wird ein neues, kostengünstiges und ressourcenschonendes Verfahren zur Herstellung dieser submikronen Ionenaustauscherpartikeln beschrieben. Dabei werden kommerziell erhältliche Ionenaustauscherpartikel auf Polymerbasis in unterschiedlichen Mühlen mit bewegten Mahlkörpern unter Raumtemperatur zerkleinert. Die porösen Polymerpartikel können so bis in den submikronen Größenbereich zerkleinert werden, ohne dass dabei die Ionenaustauschkapazität nennenswert reduziert wird.
A Process‐Structure Investigation of Aluminum Oxide and Oxycarbide Thin Films prepared by Direct Liquid Injection CVD of Dimethylaluminum Isopropoxide (DMAI)
Authors: Baggetto Loïc , Charvillat Cédric , Esvan Jérôme , Thébault Yannick , Samélor Diane , Vergnes Hugues , Caussat Brigitte , Gleizes Alain , Vahlas Constantin 
Published: November 2015

AbstractWe present the direct liquid injection CVD of aluminum oxide and oxycarbide thin films using dimethylaluminum isopropoxide at high process temperature (500–700 °C) with the addition of O2 gas, and at low temperature (150–300 °C) with the addition of H2O vapor. Very smooth films with typical roughness values lower than 2 nm are obtained. The thin films are composed of an amorphous material. The composition evolves as a function of temperature from that of a partial hydroxide to a stoichiometric oxide at low deposition temperature (150–300 °C), and from that of a stoichiometric oxide to a mixture of an oxide with an (oxy) carbide at higher temperature (500–700 °C).
The effect of retinol binding protein on the proteome of C2C12 muscle cells
Authors: Young Pamela A. , Leonard Siobhán , Martin Darren S. D. , Findlay John B. C. 
Published: November 2015

AbstractBackgroundRetinol binding protein (RBP) and its membrane receptor, STRA6, are vital for the management of vitamin A in the body. Recently, elevated serum RBP levels have been implicated as a contributing factor to the development of insulin resistance and type 2 diabetes. However, conflicting opinions exist as to how these increased levels can cause insulin resistance.MethodsIn order to better understand the influences of RBP, a proteomic study was devised to determine the direct effect of RBP on a mouse muscle cell line, because the muscle is the principal site of insulin induced glucose uptake. C2C12 cells were treated with RBP for 16 h and the proteome analysed for alterations in protein abundance and phosphorylation by 2‐DE.ResultsA number of changes were observed in response to retinol binding protein treatment, of which the most interesting were decreased levels of the phosphatase, protein phosphatase 1 β. This phosphatase is responsible for regulating glycogen synthase and glycogen phosphorylase, the rate‐limiting enzymes involved in glycogen storage and utilization. Retinol binding protein treatment resulted in increased phosphorylation and inhibition of glycogen synthase, with detrimental effects on insulin stimulated glycogen production in these cells.ConclusionThe results indicate that RBP may have a negative effect on energy storage in the cell and could contribute to the development of insulin resistance in muscle tissue. Understanding how retinol binding protein influences insulin resistance may reveal novel strategies to target this disease. Copyright © 2015 John Wiley & Sons, Ltd.
Electron‐Rich Aromatic 1,3‐Heterophospholes – Recent Syntheses and Impact of High Electron Density at σ2P on the Reactivity
Authors: Heinicke Joachim W. 
Published: November 2015

AbstractThis account reviews recent syntheses, properties, and the reactivity of electron‐rich aromatic 1,3‐heterophospholes, with the focus on benzazaphospholes, but also with inclusion of 1,2,4‐diazaphospholes containing the N–C=P–C motif and related O‐ and S‐containing heterocycles. Effects of the high electron density at phosphorus, a consequence of the position of the lone‐pair donating nitrogen atom in conjugation with dicoordinated (σ2) phosphorus and of the absence of P–N bonds, are illuminated by comparison of selected properties and reactions with those of less electron‐rich heterophospholes and phosphinines. Particular features of the electron‐rich heterocycles are CH‐lithiations of the P=CH fragment by tBuLi without addition at the P=C double bond in polar media, occurrence of inverse addition besides normal addition in less polar solutions, P‐alkylation and catalytic P‐arylation, and – last but not least – the avoidance of σ‐coordination of non‐zerovalent d10 transition metals within the ring plane in favor of μ2‐P and/or tilted η1‐P coordination.
Shelf life and quality of olive oil filtered without vertical centrifugation
Authors: Fortini Martina , Migliorini Marzia , Cherubini Chiara , Cecchi Lorenzo , Guerrini Lorenzo , Masella Piernicola , Parenti Alessandro 
Published: November 2015

This study evaluates the effect of filter press filtration on the shelf life of extra virgin olive oil (EVOO). Olives were harvested and processed on the same day by a continuous industrial plant equipped with a hammer crusher, a vertical malaxator, and a decanter. One part of the oil obtained was bottled in 0.5 liter dark‐green bottles with headspace representing a quarter of the bottle's volume (cloudy oil). The other part was filtered (using a filter press) directly after decanting and manually bottled using the same procedure (filtered oil). All samples were stored in a purpose‐built chamber and periodically analyzed. Samples were characterized by their water content, free acidity, peroxide value, specific extinction coefficients (K232 and K268), total chlorophyll, tocopherols, total phenolic compounds, HPLC phenolic profile, volatile compounds, fatty acid composition, and sensory analysis. Immediately after filtration, the only differences that could be detected were related to turbidity and total solids. In the subsequent analyses, filtered oil retained superior nutritional and sensory characteristics than cloudy oil. More importantly, the filtered oil remained at the standard required for categorization as “extra‐virgin olive oil” for longer.Practical applications: The article describes the effect of the filtration without vertical centrifugation on the olive oil quality. Shelf life tests have been performed to evaluate the changes in chemical and sensorial properties of olive oils. Since the filtration and its timing is controversial in the literature, a complete investigation, which considers the storage, is required. Furthermore, this is, to the best of authors knowledge, the first study focusing on the changes of oils produced without vertical centrifuge.This study evaluates the effect of filter press filtration on the shelf life of extra virgin olive oil (EVOO). Olives were harvested and processed on the same day by a continuous industrial plant equipped with a hammer crusher, a vertical malaxator, and a decanter. One part of the oil obtained was bottled (cloudy oil). The other part was filtered (using a filter press) directly after decanting and manually bottled using the same procedure (filtered oil). All samples were stored in a purpose‐built chamber and periodically analyzed. The results show a less degraded phenolic fraction in the filtered olive oils. In fact, compounds such as Tyrosol and Hydroxytyrosol, which are the final product of hydrolysis of secoiridoids, remain stable in filtered oils and increase in cloudy. Moreover, filtered olive oils have a better sensory profile than the cloudy along the shelf life. These data are confirmed by the GC‐MS analysis. The results confirm that filtration is essential in order to maintain the nutritional characteristics of the oil, and slow the onset of the main defects.
Base‐Induced One‐Pot Preparation of N‐ or P‐Substituted Alkynes
Authors: Zhang Yang , Zhang Yanqin , Xiao Jing , Peng Zhihong , Dong Wanrong , An Delie 
Published: November 2015

AbstractAn efficient method for the formation of C(sp)–N or C(sp)–P bonds is described. The facile transformation proceeds under mild conditions (0 or –20 °C) in a one‐pot manner, and does not require transition‐metal catalysts. The base‐induced protocol exhibits good functional group tolerance (up to 44 examples) and high efficiency (up to 94 % yield) towards rare heteroatom‐substituted acetylenes (N or P). Furthermore, the proposed mechanism was supported by the isolation of a key intermediate.
Ionically‐Functionalized Poly(thiophene) Conductive Polymers as Binders for Silicon and Graphite Anodes for Li‐Ion Batteries
Authors: Salem Nuha , Lavrisa Matt , Abu‐Lebdeh Yaser 
Published: November 2015

AbstractNext‐generation anode materials for Li‐ion batteries such as silicon can lead to ten times more capacity than the state‐of‐the‐art graphite. However, novel binders are required to overcome the detrimental effects of volume changes during battery cycling of silicon because of the poor chemical interaction and electrical conductivity between silicon and the binder. Most studies focus on either ionic binders or electrically conductive binders, but herein it was demonstrated that a new family of polymers based on electrically conductive poly(thiophene) functionalized with an ionic alkyl carboxylate groups of various lengths can successfully work as multifunctional binders for silicon and commercial graphite anodes in Li‐ion battery half‐cells. It was determined that the polymer with shorter side chain (PT‐3‐LiA) gives the highest reversible capacity upon pairing with graphite or silicon, reaching 3000 mAh g−1 in the case of the latter, a capacity 500 mAh g−1 (≈22 %) higher than those obtained with the electrically, but non‐ionically, conductive PEDOT:PSS binder and the ionically, but non‐electrically, conductive sodium carboxymethyl cellulose (NaCMC) binder. It is demonstrated that the superior performance of this new type of multifunctional binders can be attributed to their ability to maintain their doping level and conductivity as well as due to good interaction with the silicon surface during cycling.
The identity and revised circumscription of Centaurea iranshahrii (Asteraceae, Cardueae–Centaureinae) in Iran
Authors: Negaresh Kazem , Rahiminejad Mohammad Reza 
Published: November 2015

AbstractNew findings and a completed description are presented for Centaurea iranshahrii Wagenitz & Esfand (Asteraceae, Cardueae, Centaureinae). By adding new localities the distributional range of this species is circumscribed for the first time. Centaurea elymaitica Mozaff. is placed to synonymy of C. iranshahrii here. In addition, the only record of C. gudrunensis Boiss. & Hausskn. from Iran is rejected as referable to C. iranshahrii. Finally, the distribution and ecology of C. iranshahrii are presented and shown. (© 2015 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Notes on Potentilla L. (Rosaceae) from the Altai. 2. New species from South Siberia and West Mongolia
Authors: Kechaykin Alexey , Kutsev Maxim 
Published: November 2015

AbstractTwo new taxa of Potentilla found in the Altai mountain region are described and illustrated: P. smirnovii from Central Altai, P. schmakovii from Mongolian Altai. (© 2015 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)