bluuebunny/crossref_metadata_2025_split huggingface dataset:
Factors Associated with the Opinion on Self-Care of Elderly in Southernmost Provinces, Thailand
Authors: Masamae Matureedee , McNeil Rhysa , Eso Mayuening 
Published: July 2024

Background and Aims: Self-care is crucial for the elderly since it allows everyone to have a healthy life, boost immunity, prevent sickness, care for themselves when unwell, and continue to perform everyday duties in their own homes. This study aimed to investigate the factors influencing the elderly's opinions on self-care in the southernmost provinces of Thailand.
Methodology: This quantitative study used data collected by the Deep South Coordination Center from 271 elderly people in Pattani. The independent variable included demographic factors and health conditions. The outcome variable was a 4-point rating scale opinion on the self-care of the elderly. Descriptive statistics were employed to illustrate the sample's characteristics. Factor analysis was used to reduce the number of outcome variables. Multiple linear regression was used to examine the relationship between the outcome variables and the independent variables.
Results: Eighteen outcome variables were categorized into three factors consisting of positive self-management, health preparation, and doing things for great pleasure. Elderly people who could walk with their spouse or family were more likely to have positive self-management and health preparation than those who lived alone or were separated and could not walk. Elderly people who did not engage in health-risk activities and could use public transportation independently were more likely to enjoy themselves than those who could not.
Conclusion: The findings might improve the quality of self-care among the elderly to live better in their current societal situation. This can encourage care healthcare providers to promote daily living practices among the elderly.
Stalin’s Empire in the Fight Against the Ukrainian Insurgent Movement at the Final Stage of the Second World War 1944–1945): The Role of the Red Army
Authors: Hrynevych Vladyslav 
Published: July 2024

This article, based on a wide array of archival documents, presents the anal­ysis of military confrontation between the Stalinist Empire and the Ukrainian insurgent movement in Western Ukraine. Special attention is paid to the role of the Red Army, which, in addition to joint military punitive operations together with the NKVD itself resorted to organising anti-insurgency military measures and took an active part in such activi­ties aimed at destroying the Ukrainian Insurgent Army (Ukraiinska povstanska armia – hereafter UPA) and the underground Organisation of Ukrainian Nationalists (hereafter – OUN) using such measures as deportation and resettlement of the local population from the front-line zone, military mobilisations and repressions against the families of UPA members. The author concludes that the war of the Red Empire against the Ukrainian na­tional liberation movement embroiled significant masses of civilian population into its merciless millstones, which led to its barbarisation, so this war by its nature and devas­tating consequences can be considered in essence as the genocidal extermination of the Ukrainian people.
SOFT SKILLS TRAJECTORY. Why educators need soft skills?
Authors: Марченко Е.А. 
Published: July 2024

В статье рассматривается важность развития «гибких» навыков у педагогов и их влияние на образовательный процесс. В современном мире, где традиционные подходы к обучению часто не успевают за быстро меняющимися социальными и технологическими условиями, «гибкие» навыки становятся ключевыми для успешного преподавания. Автор анализирует, как такие навыки, как коммуникация, сочувствие, лидерство, работа в команде, самосознание, позволяют учителям создавать позитивную и инклюзивную учебную среду. Кроме того, акцентируется важность развития «гибких» навыков у директоров школ, которые способствуют формированию сильных и сплочённых команд, улучшению взаимодействия с родителями и общественностью, а также повышению общей эффективности и репутации школы.
The article discusses the significance of developing soft skills in educators and their impact on the educational process. In today's world, where traditional approaches to teaching often fail to keep pace with rapidly changing social and technological conditions, soft skills become key to successful teaching. The author analyses how such skills as communication, empathy, leadership, teamwork and self-awareness enable teachers to create positive and inclusive learning environments. It also emphasises the importance of developing soft skills in school principals, which contribute to building strong and cohesive teams, improving engagement with parents and the community, and enhancing the overall effectiveness and reputation of the school.
Мақалада мұғалімдердің икемді дағдыларын дамытудың маңызы және олардың білім беру процесіне әсері қарастырылады. Дәстүрлі оқыту тәсілдері жылдам өзгеретін әлеуметтік және технологиялық жағдайларға ілесе алмайтын қазіргі әлемде икемді дағдылар табысты оқытудың кілті болып табылады. Автор коммуникация, эмпатия, көшбасшылық, командалық жұмыс, өзін-өзі тану сияқты дағдылардың мұғалімдерге жағымды және инклюзивті оқу ортасын құруға қандай мүмкіндік беретінін талдайды. Сонымен қатар, мықты және ұйымшыл командаларды қалыптастыруға, ата-аналармен және қоғаммен қарым-қатынасты жақсартуға, мектептің жалпы тиімділігі мен беделін арттыруға ықпал ететін мектеп директорларының икемді дағдыларын дамытудың маңыздылығы атап өтіледі.
DEVELOPMENT OF SOFT SKILLS IN COLLEGE STUDENTS. Unified education programme
Authors: Дроженко Г.Г. 
Published: July 2024

В статье представлены результаты исследования «гибких» навыков обучающихся 1-го курса профессионально-технического колледжа в контексте реализации Единой программы воспитания.
The article presents the results of a study of 1st year students of a vocational college on the problem of soft skills development. The results of the study are considered through the prism of the implementation of a Unified education program.
Мақалада икемді дағдыларды дамыту мәселесі бойынша кәсіптік-техникалық колледждің 1 курс білім алушыларының зерттеу нәтижелері келтірілген. Зерттеу нәтижелері Біртұтас тәрбие бағдарламасын жүзеге асыру призмасы арқылы қарастырылады.
Enhancing Tracheostomy Care Proficiency: Evaluating the Impact of Online Interprofessional Tracheostomy Education Program
Authors: Morris Linda L. , Bines Ann , Earnest Katherine , McCarter-Koppes Sarah , Smalls-Smyth Arlene , Wong Jasin 
Published: July 2024

Background Evidence suggests that many clinicians lack confidence in managing tracheostomy patients effectively. This gap is further exacerbated by the influx of new healthcare providers who may have received insufficient training in tracheostomy care. Consequently, there is a pressing need to evaluate the effectiveness of training interventions to enhance clinicians’ confidence and competence in tracheostomy care. This study aims to assess the effectiveness of an interprofessional online training program in improving healthcare professionals’ confidence and proficiency in tracheostomy care. Local Problem Interprofessional healthcare providers’ have expressed lack of experience and confidence in managing tracheostomy patients. Method We used a pre-test, post-test approach, assessing self-reports of caregiver experience and confidence regarding tracheostomy care. Participants included nurses, allied health therapists, and respiratory therapists at a large urban inpatient rehabilitation hospital. Interventions An interprofessional online tracheostomy training program was developed for staff as the last step of a comprehensive quality improvement project. Results Ninety-eight (98) subjects responded to the pre-training survey, and 35 responded to the post-training survey. Prior to training, nurses reported being “very confident” in suctioning (70.9%) and stoma care (58.2%), but less so in other aspects of care. Fewer allied health therapists reported confidence in tracheostomy-related skills; however, respiratory therapists reported proficiency in most skills. Clinicians with more work experience exhibited higher levels of confidence compared to new graduates in stoma care and cleaning, emergency care, and capping and speaking valve precautions. However, 40-73% of clinicians still reported lower levels of confidence in tracheostomy-related skills. Following training, there was an increased trend of confidence in most skills, especially for nurses; however, confidence remained low in managing tracheostomy emergencies (17.6%) and identifying the differences between tracheostomy and laryngectomy (20%). Conclusions Online training may improve confidence in tracheostomy care, but critical content may necessitate multiple primary teaching methods to achieve mastery. Additional methods such as simulations, hands-on skills practice, and bedside rounds can be beneficial for material synthesis.
In-line Mechanical Insufflation-Exsufflation as an Alternative to Invasive Suction for Secretion Management in Ventilated Patients, A Randomized Controlled Trial
Authors: Be'eri Eliezer , Ming Jia , Dan-nuo Han , Jianxin Zhou , Min Xu , Zhong-hua Shi , Linton David M 
Published: July 2024

Background Catheter suction (CS), the standard method for airway secretion management in tracheostomized or intubated patients, is invasive and has significant hemodynamic and traumatic side effects. In-line mechanical insufflation-exsufflation (IL-MIE) is a new, non-invasive technology that clears secretions by simulating coughs without interrupting ongoing mechanical ventilation. It is not known whether IL-MIE can be safely and effectively used as an alternative to CS in these ventilated patients. Methods A randomized controlled study was conducted comparing a standard protocol of CS with automatic IL-MIE (CoughSync, Ruxin Medical Systems, Beijing) performed every 30 minutes, with CS added only if needed, in post-operative mechanically ventilated patients. Results Over 8 hours, the IL-MIE cohort required significantly fewer CS treatments per patient than the control cohort (mean 0.4 vs. 2.6, p < 0.001, n = 60 for both cohorts). Seventy-three percent of the IL-MIE subjects required no CS at all, compared to 2% in the control group (p < 0.001). At 8 hours, IL-MIE subjects had a significantly lower heart rate than control subjects (mean 90 vs. 96, p = 0.047), implying a hemodynamic advantage to IL-MIE. No significant adverse events were associated with IL-MIE. Conclusions IL-MIE minimizes the need for invasive CS without detriment to ventilatory management in mechanically ventilated patients.
KECERDASAN SPIRITUAL SEBAGAI FAKTOR INTERNAL YANG MEMPENGARUHI PRESTASI BELAJAR MAHASISWA
Authors: Nurhasanah  , Deskoni  , Dwi Hasmidyani  
Published: July 2024

Penelitian ini bertujuan untuk membuktikan apakah terdapat pengaruh kecerdasan spiritual terhadap prestasi belajar mahasiswa Pendidikan Ekonomi FKIP Universitas Sriwijaya tahun akademik 2018. Teknik pengumpulan data yang digunakan adalah angket dan dokumentasi. Validitas instrumen dilakukan menggunakan rumus Korelasi Product Moment dan uji reliabilitas menggunakan rumus Alpha Cronbach. Teknik pengambilan sampel menggunakan teknik sampling jenuh. Sampel dalam penelitian ini adalah seluruh mahasiswa Pendidikan Ekonomi FKIP Universitas Sriwijaya angkatan 2018 yang berjumlah 73 orang. Teknik analisis data kecerdasan spiritual diperoleh dari hasil angket, dan analisis data prestasi belajar diperoleh dari hasil dokumentasi yang ditunjukkan dengan indeks prestasi belajar (IPK). Berdasarkan perhitungan uji-t yang menunjukkan bahwa thitung= 6,3430<ttabel=1,9939 maka Ho ditolak dan Ha diterima. Hal ini menunjukkan bahwa terdapat pengaruh kecerdasan spiritual terhadap prestasi belajar mahasiswa Pendidikan Ekonomi FKIP Universitas Sriwijaya tahun akademik 2018. Kemudian dilakukan pengujian determinan untuk mengetahui seberapa besar variabel kecerdasan spiritual mempengaruhi variabel prestasi belajar diperoleh nilai sebesar 36% sedangkan 64% dipengaruhi faktor variabel lain diluar penelitian ini.
Management of Carrot Root Borer, Melanagromyza sp. in Carrot Dacus carota L
Authors: Ramesha N M , Asritha Chava , Rafee C M , Hegde M G , Hiremath S M 
Published: July 2024

A field experiment was conducted during rabi/summer 2021-22 at Nagaral village of Ron taluka in Gadag district, Karnataka to identify the appropriate causal agent for carrot root damage and to assess the field efficiency of different insecticide molecules against agromyzid fly, Melanagromyza sp. The experiment was laid out in randomized block design with 11 treatments replicated thrice. The crop was cultivated during 1st January 2022 as per the recommended package of practices except the insect protection measures. Observation on per cent infestation by agromyzid fly was recorded in each treatment by adopting a destructive sample technique from 40 days after sowing to 100 days after sowing. Per cent damage and yield parameters were subjected to one-way ANOVA and Duncan’s Multiple Range Test. Result indicated that highest reduction of agromyzid fly damage over untreated control was recorded in treatment with soil application with chlorantraniliprole 0.4% GR @ 10 kg/ha at 35 DAS (71.86% reduction over control) and soil application with fipronil 0.3 % GR @ 20 kg/ha at 35 DAS with 69.10 per cent reduction over control. These are followed by seed treatment with cyantraniliprole 19.8% + thiamethoxam 19.8% @10 ml/kg, seed treatment with thiamethoxam 30 FS @ 10 ml/kg, seed treatment with imidacloprid 600 FS @ 10ml/kg and soil drenching with chlorpyriphos 20% EC @ 3 ml/l at 35 DAS, these treatments registered a maximum reduction of agromyzid fly viz., 69%, 58.03%, 56.79% and 58.03%, respectively.
Intraskeletal isotopic compositions (δ13C, δ15N) of bone collagen: Nonpathological and pathological variation
Authors: Olsen Karyn C. , White Christine D. , Longstaffe Fred J. , von Heyking Kristin , McGlynn George , Grupe Gisela , Rühli Frank J. 
Published: December 2013

ABSTRACTPaleodiet research traditionally interprets differences in collagen isotopic compositions (δ13C, δ15N) as indicators of dietary distinction even though physiological processes likely play some role in creating variation. This research investigates the degree to which bone collagen δ13C and δ15N values normally vary within the skeleton and examines the influence of several diseases common to ancient populations on these isotopic compositions. The samples derive from two medieval German cemeteries and one Swiss reference collection and include examples of metabolic disease (rickets/osteomalacia), degenerative joint disease (osteoarthritis), trauma (fracture), infection (osteomyelitis), and inflammation (periostitis). A separate subset of visibly nonpathological skeletal elements from the German collections established normal intraindividual variation. For each disease type, tests compared bone lesion samples to those near and distant to the lesions sites. Results show that normal (nonpathological) skeletons exhibit limited intraskeletal variation in carbon‐ and nitrogen‐isotope ratios, suggesting that sampling of distinct elements is appropriate for paleodiet studies. In contrast, individuals with osteomyelitis, healed fractures, and osteoarthritis exhibit significant intraskeletal differences in isotope values, depending on whether one is comparing lesions to near or to distant sites. Skeletons with periostitis result in significant intraskeletal differences in nitrogen isotope values only, while those with rickets/osteomalacia do not exhibit significant intraskeletal differences. Based on these results, we suggest that paleodiet researchers avoid sampling collagen at or close to lesion sites because the isotope values may be reflecting both altered metabolic processes and differences in diet relative to others in the population. Am J Phys Anthropol 153:598–604, 2014. © 2013 Wiley Periodicals, Inc.
Maternal short stature does not predict their children's fatness indicators in a nutritional dual‐burden sample of urban Mexican Maya
Authors: Wilson Hannah J. , Dickinson Federico , Griffiths Paula L. , Bogin Barry , Hobbs Matthew , Varela‐Silva M. Inês 
Published: December 2013

ABSTRACTThe co‐existence of very short stature due to poor chronic environment in early life and obesity is becoming a public health concern in rapidly transitioning populations with high levels of poverty. Individuals who have very short stature seem to be at an increased risk of obesity in times of relative caloric abundance. Increasing evidence shows that an individual is influenced by exposures in previous generations. This study assesses whether maternal poor early life environment predicts her child's adiposity using cross sectional design on Maya schoolchildren aged 7–9 and their mothers (n = 57 pairs). We compared maternal chronic early life environment (stature) with her child's adiposity (body mass index [BMI] z‐score, waist circumference z‐score, and percentage body fat) using multiple linear regression, controlling for the child's own environmental exposures (household sanitation and maternal parity). The research was performed in the south of Merida, Yucatan, Mexico, a low socioeconomic urban area in an upper middle income country. The Maya mothers were very short, with a mean stature of 147 cm. The children had fairly high adiposity levels, with BMI and waist circumference z‐scores above the reference median. Maternal stature did not significantly predict any child adiposity indicator. There does not appear to be an intergenerational component of maternal early life chronic under‐nutrition on her child's obesity risk within this free living population living in poverty. These results suggest that the co‐existence of very short stature and obesity appears to be primarily due to exposures and experiences within a generation rather than across generations. Am J Phys Anthropol 153:627–634, 2014. © 2013 Wiley Periodicals, Inc.
Chondrocyte β‐Catenin Signaling Regulates Postnatal Bone Remodeling Through Modulation of Osteoclast Formation in a Murine Model
Authors: Wang Baoli , Jin Hongting , Zhu Mei , Li Jia , Zhao Lan , Zhang Yejia , Tang Dezhi , Xiao Guozhi , Xing Lianping , Boyce Brendan F. , Chen Di 
Published: December 2013

ObjectiveTo investigate whether β‐catenin signaling in chondrocytes regulates osteoclastogenesis, thereby contributing to postnatal bone growth and bone remodeling.MethodsMice with conditional knockout (cKO) or conditional activation (cAct) of chondrocyte‐specific β‐catenin were generated. Changes in bone mass, osteoclast numbers, and osteoblast activity were examined. The mechanisms by which β‐catenin signaling in chondrocytes regulates osteoclast formation were determined.ResultsThe β‐catenin cKO mice developed localized bone loss, whereas cAct mice developed a high bone mass phenotype. Histologic findings suggested that these phenotypes were caused primarily by impaired osteoclast formation, rather than impaired bone formation. Further molecular signaling analyses revealed that β‐catenin signaling controlled this process by regulating the expression of the RANKL and osteoprotegerin (OPG) genes in chondrocytes. Activation of β‐catenin signaling in chondrocytes suppressed Rankl gene transcription through a glucocorticoid receptor–dependent mechanism. The severe bone loss phenotype observed in β‐catenin cKO mice was largely restored by treatment with human recombinant OPG or transgenic overexpression of Opg in chondrocytes.Conclusionβ‐catenin signaling in chondrocytes plays a key role in postnatal bone growth and bone remodeling through its regulation of osteoclast formation.
Brief Report: Whole‐Exome Sequencing Revealing Somatic NLRP3 Mosaicism in a Patient With Chronic Infantile Neurologic, Cutaneous, Articular Syndrome
Authors: Omoyinmi Ebun , Melo Gomes Sónia , Standing Ariane , Rowczenio Dorota M. , Eleftheriou Despina , Klein Nigel , Aróstegui Juan I. , Lachmann Helen J. , Hawkins Philip N. , Brogan Paul A. 
Published: December 2013

ObjectiveTo identify the genetic cause of chronic infantile neurologic, cutaneous, articular syndrome (CINCA syndrome) using whole‐exome sequencing in a child who had typical clinical features but who was NLRP3 mutation negative based on conventional Sanger sequencing.MethodsWe performed whole‐exome sequencing on DNA from peripheral blood, using Illumina TruSeq Exome capture and the HiSeq sequencing platform. Exome data were analyzed in the Galaxy Web‐based suite. Whole‐exome sequencing findings were confirmed by massively parallel sequencing.ResultsAnalysis of variants in known autoinflammatory genes led to the identification of the pathogenic p.F556L NLRP3 missense mutation in 17.7% of Illumina reads (25 of 141). No new candidate genes were identified. Massively parallel sequencing of DNA from peripheral blood (performed in duplicate) unequivocally confirmed the presence of this mutation in 14.5% of alleles. Reexamination of the original Sanger chromatograms revealed a small peak at nucleotide position c.1698 corresponding to the mutated allele. This had initially been regarded as background noise, but in retrospect is completely consistent with somatic mosaicism for the p.F556L NLRP3 mutation in this child with CINCA syndrome.ConclusionThis is the first description of somatic NLRP3 mosaicism detected using whole‐exome sequencing in a “mutation‐negative” patient with CINCA syndrome. Our findings suggest that whole‐exome sequencing could be an important diagnostic tool for detecting somatic mosaicism, as well as for the discovery of novel causative gene mutations, in patients with clinical features of cryopyrin‐associated periodic syndromes who are NLRP3 mutation negative by conventional sequencing. This approach could also be applicable to patients with other autosomal‐dominant autoinflammatory diseases characterized by gain‐of‐function mutations who are mutation negative by conventional Sanger sequencing.
Combination of Tumor Necrosis Factor α and Interleukin‐6 Induces Mouse Osteoclast‐like Cells With Bone Resorption Activity Both In Vitro and In Vivo
Authors: Yokota Kazuhiro , Sato Kojiro , Miyazaki Takashi , Kitaura Hideki , Kayama Hisako , Miyoshi Fumihiko , Araki Yasuto , Akiyama Yuji , Takeda Kiyoshi , Mimura Toshihide 
Published: December 2013

ObjectiveTo clarify the function of osteoclast‐like multinuclear cells differentiated from bone marrow–derived macrophages (BMMs) by a combination of tumor necrosis factor α (TNFα) and interleukin‐6 (IL‐6), and to investigate the molecular mechanisms underlying the differentiation.MethodsBMMs were stimulated by TNFα and/or IL‐6. The cells were then compared with conventional osteoclasts differentiated in vitro by RANKL. An in vitro pit formation assay on dentine slices and an in vivo resorption assay of calvarial bones were performed. We also evaluated the activities and expression levels of NF‐κB, c‐Fos, and NF‐ATc1, which are essential to the differentiation of conventional osteoclasts. Small interfering RNA was used to knock down c‐Fos. The effects of genetic ablation of STAT‐3 and pharmacologic inhibitors of NF‐AT, JAK, and ERK were also studied.ResultsOsteoclast‐like cell differentiation depended on TNFα and IL‐6 and was not inhibited by osteoprotegerin. These differentiated cells were associated with both in vitro and in vivo bone resorption activity. TNFα and IL‐6 had a synergistic effect on the activity and expression of c‐Fos. Knockdown of c‐Fos inhibited the expression of NF‐ATc1 and the differentiation of osteoclast‐like cells. All of these inhibitors blocked differentiation of the cells in vitro, but surprisingly, the conditional knockout of STAT‐3 did not. Tofacitinib also inhibited the bone destruction caused by TNFα and IL‐6 in vivo.ConclusionOur results demonstrate that a combination of the inflammatory cytokines TNFα and IL‐6 can induce osteoclast‐like cells that have in vitro and in vivo bone‐resorptive activity.