bluuebunny/crossref_metadata_2025_split huggingface dataset:
A preliminary study on the effects of substituting fishmeal with defatted black soldier fly (Hermetia illucens) larval meal on Asian seabass (Lates calcarifer) juveniles: Growth performance, feed efficiency, nutrient composition, disease resistance, and economic returns
Authors: Liu Yun , Andin Victor Charlie , Chor Wei‐Kang , Gunasekaran Baskaran , Chong Chou‐Min , Lee Po‐Tsang , Loh Jiun‐Yan 
Published: August 2024

AbstractThis study aims to develop an alternative aquafeed derived from insect meal for Lates calcarifer juveniles, with the objectives of exploring the physiological performance, biological parameters, and economic analysis of substituting fishmeal (FM) with defatted black soldier fly (Hermetia illucens) larvae (BSFL) as part of the diet of L. calcarifer juveniles. Five practical diets were formulated to include 0% (BSFL0, serves as control group), 5% (BSFL5), 10% (BSFL10), 15% (BSFL15), and 20% (BSFL20) of BSFL meal, partially or fully replacing FM, respectively. Each diet was randomly assigned to triplicate groups of 30 fish (10.70 ± 0.07 g) per tank (300 L). The fish were fed twice daily to apparent satiation. A 56‐day feeding trial was conducted to evaluate the impacts of defatted BSFL meal replacing FM on the growth performance, feed efficiency, composition analysis of fish muscle, cumulative mortality rate challenged with Vibrio parahaemolyticus, and economic returns of L. calcarifer. These results show that differences in weight gain and specific growth rate among the different treatments were statistically significant (p < 0.05), except for the absence of significant variation (p < 0.05) between BSFL0 and BSFL5, and followed by BSFL10 > BSFL0 > BSFL5 > BSFL15 > BSFL20. However, the feed conversion ratio and protein efficiency ratio showed the opposite trend as above. Although the diets experienced a decline in crude protein content and an increase in crude fat content with the increasing proportion of BSFL substituting FM, the crude protein and fat content of fish muscle were only slightly influenced. It is worth mentioning that levels of nonessential amino acids, delicious amino acids, saturated fatty acids, omega‐6, omega‐9 in BSFL10 group all showed an increase compared with the control group. After a 7‐day challenge test with V. parahaemolyticus, the cumulative mortality rates of the BSFL5 and BSFL10 groups, respectively, dropped to 5.20%, 5.28% compared to the control group's 16.88%; however, the mortality rates of BSFL15 (34.67%) and BSFL20 (41.77%) groups were found to be significantly (p < 0.05) increased. From an economic perspective, the incidence cost for each experimental group showed a trend as BSFL10 < BSFL0 < BSFL5 < BSFL15 < BSFL20, whereas the profit index in each treatment exhibited the opposite trend as above. It was concluded that low (5%) or moderate (10%) levels of BSFL substituting FM in aquaculture feed could improve the physiological performances, disease resistance, and economic returns of L. calcarifer. However, excessive substitution (>15%) leads to a negative effect. From an economic point of view, 10% inclusion of BSFL in practical diets is recommended for L. calcarifer juveniles.
Time‐Series Factor Modeling and Selection
Authors: Michaelides Michael 
Published: August 2024

AbstractThe article proposes a statistical time‐series factor model that incorporates deterministic orthogonal trend polynomials. Such polynomials allow capturing variation in returns without initially identifying a set of robust time‐series factors. This modeling approach can serve as a coherent basis for testing and selecting the most relevant factors among a set of possible ones. Additionally, it can help identify whether any factors are missing from a time‐series asset pricing model. The use of the proposed model and empirical strategy is illustrated by two empirical applications from the literature, yielding results related to the Fama‐French five‐factor model and the factor zoo.
Closure methods for large defects after gastrointestinal endoscopic submucosal dissection
Authors: Gong Rui , Wang Simiao , Song Jiugang , He Zhen , Li Peng , Zhang Shutian , Sun Xiujing 
Published: August 2024

AbstractNowadays, endoscopic submucosal dissection (ESD) is commonly performed for the removal of large gastrointestinal lesions. Endoscopic mucosal defect closure after ESD is vital to avoid adverse events. In recent years, many innovative instruments have emerged and proved to be beneficial. In this paper, we conducted a thorough literature review and summarized the closure methods for large‐size post‐ESD mucosal defects over decades. We separated these methods into five categories based on the operational principle: “side closure” method, “ring closure” method, “layered closure” method, “hand suturing closure” method, and “specially designed device closure” method. Side closure with clips assisted by instruments such as threads or loops is applicable for each segment of the gastrointestinal tract to prevent postoperative bleeding. If the defect tension is too large to close with the traditional side closure methods, zigzag closure and ring closure could be applied to gather the bilateral defect edges together and achieve continuous closure. In the stomach and rectum with a high risk of submucosal dead space between the submucosa and muscular layers, side closure methods with muscle layer grasping clip or layered closure methods could enable the involvement of the deep submucosa and muscle layers. The ring closure method and specially designed devices including over‐the‐scope clip, Overstitch, and X‐tack could resolve perforation effectively. Individual closure method requires endoscope reinsertion or sophisticated operation, which may be limited by the deep location and the narrow lumen, respectively. Although specially designed devices are expected to offer promising prospectives, the cost‐effectiveness remains to be a problem.
Impact of federal antipsychotic use policy in nursing homes on new diagnoses for approved indications in dementia residents
Authors: Shireman Theresa I. , Coulibaly Neto , Zhang Tingting , Zullo Andrew R. , Gerlach Lauren B. , Coe Antoinette B. , Daiello Lori A. , Lo Derrick , Bynum Julie P. W. 
Published: August 2024

AbstractBackgroundFederal policies targeting antipsychotic use among nursing home (NH) residents may have increased reporting of diagnoses for approved uses, including schizophrenia, Tourette's syndrome, and Huntington's Disease (called “exclusionary diagnoses” because they exclude residents from the antipsychotic quality metric). We assessed changes in new exclusionary diagnoses among long‐stay NH admissions specifically with dementia following federal policies.MethodsRetrospective, quarterly, interrupted time‐series analysis (2009–2018) of new long‐stay NH residents with dementia and no exclusionary diagnoses reported before NH admission. The National Partnership and the addition of facility level antipsychotic use to the Five Star Quality Rating system were key time exposures. Outcome was quarterly facility level predicted percentage of exclusionary diagnoses within 2 years of admission stratified by NH characteristics.ResultsFor 264,095 long‐stay admissions, mean percentage of new exclusionary diagnoses was 2.2% before the Partnership. After the Partnership, there was an unadjusted increase in the percentage over time (slope change, 0.044, p = 0.018), but the percentage never exceeded 2.9%. The Partnership contributed to a one‐time decrease in diagnoses in NHs with an intermediate percentage of Black residents (−1.29%, p = 0.004). Before the Partnership, diagnoses were increasing among not‐for‐profit relative to for‐profit NHs (0.044; p = 0.012), but after the Partnership, the pattern reversed. For‐profit NHs saw an increase (+0.034, p = 0.002); not‐for‐profit NHs experienced a decrease (−0.014, p = 0.039). Quality Rating modifications had no significant effect.ConclusionsExclusionary diagnosis reporting among long‐stay NH residents with dementia, the group most at risk from antipsychotics, did not increase in response to federal policies. Evaluation of reasons for the observed increase in exclusionary diagnoses among non‐dementia NH residents is warranted along with continued attention to how to incentivize the appropriate use of medications in residents with dementia that is crucial for high‐quality NH care.
“Effectiveness of minimally invasive injectable modalities in the management of androgenetic alopecia among adults—A systematic review”
Authors: Kumar Vaibhav , Gold Michael , Jain Anuj , Mhatre Pranjal , Zaman Ungku Mohd Shahrin b Mohd , Kapoor Rinky , Shome Debraj 
Published: August 2024

AbstractBackgroundAndrogenetic alopecia is the most common cause of hair loss that affects over 50% of the world population. It is a condition that is multifactorial in origin, with no specific causative factor, making treatment an enervating experience for the patient as well as the doctor. In recent times, a number of modalities have been introduced for the treatment of alopecia. However, the evidence supporting them is unstructured and sparse. Therefore, this article aims to explore the current trends in minimally invasive treatments for the management of androgenetic alopecia.MethodsAn in‐depth literature search on injectables used in the treatment of alopecia in PubMed/MEDLINE, Embase, PsycINFO, TRIP Cochrane Library, and Cochrane Skin databases between January 2000 and May 2023 was performed. The studies included were randomized controlled trials, non‐randomized trials, quasi trials, single arm interventions, and cohort studies.ResultsSixteen of the 1071 studies that were found during the original search were accepted in accordance with the inclusion criteria. Twelve studies assessed the effectiveness of the injectable group by comparing it to a control group consisting of saline, distilled water, and topical minoxidil. In the treatment of alopecia, dutasteride and injectable growth factor formulations achieved clinically significant results.ConclusionThe usage of injectables and topical medicines to treat hair loss has increased in the recent years. Overall results from clinical investigations, pilot studies, and trials looking at the efficacy and safety of these growth factors in the AGA show satisfactory efficacy.
Exploring the barriers, facilitators and needs to use patient outcomes in district nursing care: A multi‐method qualitative study
Authors: Veldhuizen Jessica Desirée , Van Wijngaarden Frans , Mikkers Misja Chiljon , Schuurmans Marieke Joanne , Bleijenberg Nienke 
Published: August 2024

AbstractAim and ObjectivesTo provide an in‐depth insight into the barriers, facilitators and needs of district nurses and nurse assistants on using patient outcomes in district nursing care.BackgroundAs healthcare demands grow, particularly in district nursing, there is a significant need to understand how to systematically measure and improve patient outcomes in this setting. Further investigation is needed to identify the barriers and facilitators for effective implementation.DesignA multi‐method qualitative study.MethodsOpen‐ended questions of a survey study (N = 132) were supplemented with in‐depth online focus group interviews involving district nurses and nurse assistants (N = 26) in the Netherlands. Data were analysed using thematic analysis.ResultsDifferent barriers, facilitators and needs were identified and compiled into 16 preconditions for using outcomes in district nursing care. These preconditions were summarised into six overarching themes: follow the steps of a learning healthcare system; provide patient‐centred care; promote the professional's autonomy, attitude, knowledge and skills; enhance shared responsibility and collaborations within and outside organisational boundaries; prioritise and invest in the use of outcomes; and boost the unity and appreciation for district nursing care.ConclusionsThe preconditions identified in this study are crucial for nurses, care providers, policymakers and payers in implementing the use of patient outcomes in district nursing practice. Further exploration of appropriate strategies is necessary for a successful implementation.Relevance to clinical practiceThis study represents a significant step towards implementing the use of patient outcomes in district nursing care. While most research has focused on hospitals and general practitioner settings, this study focuses on the needs for district nursing care. By identifying 16 key preconditions across themes such as patient‐centred care, professional autonomy and unity, the findings offer valuable guidance for integrating a learning healthcare system that prioritises the measurement and continuous improvement of patient outcomes in district nursing.Reporting MethodConsolidated Criteria for Reporting Qualitative Research (COREQ) guidelines.Patient of Public ContributionNo patient or public contribution.
Zooming in on the self in workplace coaching: Self‐regulation and its connection to coaching success
Authors: Mühlberger Christina , Zerle Georg , Möller Julius , Diller Sandra Julia , Greif Siegfried , Kinder Nicklas , Jonas Eva 
Published: August 2024

AbstractThe coachee's self is central to coaching. Yet the roles that different self‐related concepts play in coaching have been insufficiently studied. Specifically, self‐control and self‐regulation have been conflated or treated as identical concepts. Using the theory of personality systems interactions, we investigated how the development of self‐management competencies (SMCs) within coaching facilitates coaching success in two studies with professional samples. Additionally, we examined how coaches support coachees' development of these competencies. Study 1 employed a longitudinal design. Caregivers working as managers engaged in a 5‐month coaching programme. Goal attainment increased, need frustration decreased and the SMCs self‐regulation and self‐access increased, with self‐regulation predicting coachees' goal attainment. In Study 2, we conceptually replicated the finding that self‐regulation is positively related to coaching success. With a cross‐sectional design, we matched self‐reported data of 298 coachees with self‐reported data of their 75 respective coaches. In a structural equation model, we found that a strong coaching relationship reported by the coaches positively related to the SMCs reported by the coachees. Self‐regulation again showed the strongest effect on coaching success. These findings provide theoretical insights into the different effects of self‐regulation and self‐control on coaching effectiveness and suggest areas of focus for coaches.
Trends in plant cover derived from vegetation plot data using ordinal zero‐augmented beta regression
Authors: van Strien Arco J. , Irvine Kathryn M. , Retel Cas 
Published: August 2024

AbstractQuestionsPlant cover values in vegetation plot data are bounded between 0 and 1, and cover is typically recorded in discrete classes with non‐equal intervals. Consequently, cover data are skewed and heteroskedastic, which hampers the application of conventional regression methods. Recently developed ordinal beta regression models consider these statistical difficulties. Our primary question is whether we can detect species trends in vegetation plot time series data with this modelling approach. A second question is whether trends in cover have additional value compared to trends in occurrence, which are easier to assess for practitioners.LocationThe Netherlands, Western Europe.MethodsWe used vegetation plot data collected from 10,000 fixed plots which were surveyed once every four years during 1999–2022. We used the ordinal zero‐augmented beta regression (OZAB) model, a hierarchical model consisting of a logistic regression for presence and an ordinal beta regression for cover. We adapted the OZAB model for longitudinal data and produced estimates of cover and occurrence for each four‐year period. Thereafter we assessed trends in cover and in occurrence across all periods.ResultsWe found evidence of a trend in cover in 318 out of the 721 species (44%) with sufficient data. Most species showed similar directional trends in occurrence and percent cover. No trend in occurrence was detected for 64 species that had evidence of a trend in cover. Declining species had stronger relative changes in cover than in occurrence.ConclusionsOur model enables researchers to detect trends in cover using longitudinal vegetation plot data. Cover trends often corroborated trends in occurrence, but we also regularly found trends in cover even in the absence of evidence for trends in occurrence. Our approach thus contributes to a more complete picture of (changes in) vegetation composition based on large monitoring data sets.
Systemic risk in markets with multiple central counterparties
Authors: Veraart Luitgard Anna Maria , Aldasoro Iñaki 
Published: August 2024

AbstractWe provide a framework for modeling risk and quantifying payment shortfalls in cleared markets with multiple central counterparties (CCPs). Building on the stylized fact that clearing membership is shared among CCPs, we develop a modeling framework that captures the interconnectedness of CCPs and clearing members. We illustrate stress transmission mechanisms using simple examples as well as empirical evidence based on calibrated data. Furthermore, we show how stress mitigation tools such as variation margin gains haircutting by one CCP can have spillover effects on other CCPs. The framework can be used to enhance CCP stress‐testing, which currently relies on the “Cover 2” standard requiring CCPs to be able to withstand the default of their two largest clearing members. We show that who these two clearing members are can be significantly affected if one considers higher‐order effects arising from interconnectedness through shared clearing membership. Looking at the full network of CCPs and shared clearing members is, therefore, important from a financial stability perspective.
Anatomical compensation of retinal nerve fiber layer improves the detection of glaucoma between ethnicities
Authors: Chua Jacqueline , Li Chi , Wong Damon W. K. , Chong Rachel S. , Husain Rahat , Wong Tina T. , Vass Clemens , Cheng Ching‐Yu , Aung Tin , Schmetterer Leopold 
Published: August 2024

AbstractThe study aimed to evaluate the impact of compensating retinal nerve fiber layer (RNFL) thickness for demographic and anatomical factors on glaucoma detection in Chinese and Indian adults. A population‐based study included 1995 healthy participants (1076 Chinese and 919 Indians) to construct a multivariable linear regression compensation model. This model was applied to 357 Chinese glaucoma patients, 357 healthy Chinese, and 357 healthy Indians using Cirrus spectral‐domain optical coherence tomography (OCT). The compensated RNFL thickness considered age, refractive error, optic disc parameters, and retinal vessel density. Results showed that although the average RNFL thickness was significantly higher in Chinese participants compared to Indians, the compensation model reduced this difference to nonsignificance. Moreover, the compensation model significantly improved the area under the receiver operating characteristic curve (0.90 vs. 0.78; p<0.001), sensitivity (75% vs. 51%), and specificity (67% vs. 32%) in distinguishing Chinese glaucoma patients from healthy Indian individuals. The compensation model significantly enhanced the diagnostic accuracy of RNFL thickness in distinguishing glaucoma in the Chinese ethnic group compared to the OCT instrument's default values. These results suggest that modifying RNFL measurements based on individual characteristics can yield substantial benefits for glaucoma detection across ethnicities.
New clinicopathological concept of endometrial carcinoma with integration of histological features and molecular profiles
Authors: Yasuda Masanori 
Published: August 2024

AbstractThe dual‐stratified pathway of endometrial carcinomas (ECs) has long been dominant. However, in 2013, The Cancer Genome Atlas (TCGA) defined four EC subgroups with distinctive prognoses. Inspired by TCGA, in 2018, the Proactive Molecular Risk Classifier for Endometrial Cancer (ProMisE) provided four pragmatic molecular classifiers to apply surrogate immunohistochemical markers to TCGA subgroup categorization. These trends prompted the revision of 2020 WHO Classification of Female Genital Tumors, 5th edition (2020 WHO classification), in which four molecular subtypes are recognized: POLE‐ultramutated; mismatch repair‐deficient; p53‐mutant; and no specific molecular profile. In the 2020 WHO classification, the diagnostic algorithm is characterized by prioritizing POLEmut over other molecular abnormalities. Following the 2020 WHO classification, Federation of International Gynecology and Obstetrics (FIGO) proposed a new staging system in 2023. The updated system focuses on diagnostic parameters, such as histological type and grade, lymphovascular space invasion, and molecular alterations. These new histomolecular diagnostic concepts of ECs are being accordingly introduced into the routine pathology practice. For the first time, the 2020 WHO classification includes mesonephric‐like adenocarcinoma (MLA) as a novel histological entity, mimicking the conventional mesonephric adenocarcinoma, but is considered of Müllerian ductal origin.
Islamic Chaplaincy in North America: The State of the Field
Authors: Jalalzai Sajida 
Published: August 2024

ABSTRACTThis article surveys the state of research on Islamic chaplaincy in North America. These studies analyze the development of the profession in light of the unique spiritual, emotional, and socio‐political challenges faced by Muslims in the U.S. and Canada. Despite its novelty, this field of research spans multiple academic disciplines, including religious studies, sociology, psychology, anthropology, history, and theology. An examination of existing scholarship on Islamic chaplaincy highlights several recurrent topics of inquiry, including the roles and responsibilities of Muslim chaplains, professionalization of Islamic chaplaincy, the negotiation of Muslim women's authority, and Islamic spiritual care as a theology of engagement.
From the Third World to the Global South: Definitions of Moral Geographies of Inequality in Anti‐Colonial Intellectual Traditions
Authors: Pinheiro Claudio 
Published: August 2024

ABSTRACTFor decades, the “Third World” was an expression used to refer to regions seen as lacking prosperity and progress, on the one hand, and as a rallying call for anti‐colonial struggles on the other. The concept evoked the uneven distribution of power and wealth following World War II, replaced the forms of oppression and disparities distinctive of the former colonial world, and fostered liberatory and autonomous projects. In recent discussions on intellectual decolonization, however, the Global South became a popular way of expressing purportedly similar understandings of what I name as “moral geographies of inequality.” This article reviews the genealogies, uses, lives and afterlives of these two concepts, discussing whether the “Third World” and the “Global South” refer to one and the same; the contexts in which these terms are most commonly used; why one term has been substituted for the other; and the possible repercussions of this shift.