bluuebunny/crossref_metadata_2025_split huggingface dataset:
25-Gauge Pars Plana Vitrectomy With Medium-Term Postoperative Perfluoro-n-octane Tamponade for Inferior Retinal Detachment
Authors: Sigler Eric J. , Randolph John C. , Calzada Jorge I. , Charles Steve 
Published: January 2013

BACKGROUND AND OBJECTIVE:
To describe a series of patients with inferior retinal detachments managed with primary 25-gauge pars plana vitrectomy (PPV), 2 to 3 weeks of postoperative perfluoro-n-octane (MT-PFO) tamponade, and upright positioning followed by secondary PPV and PFO removal.

PATIENTS AND METHODS:
Interventional case series of 157 patients with inferior retinal detachments with and without proliferative vitreoretinopathy. Eyes were treated with 25-gauge PPV, endophotocoagulation, and MT-PFO tamponade. Patients underwent postoperative upright positioning followed by repeat PPV and PFO removal in a planned, staged procedure.

RESULTS:

Mean follow-up was 32 ± 4.6 months. Successful reattachment was achieved in 87.5% of 159 eyes. Main initial postoperative complications were persistent intraocular pressure (IOP) elevation in 34% (n = 54), excessive inflammation in 27% (n = 43), and PFO in the anterior chamber in 21% (n = 34). Additional complications occurring after PFO removal included cataract surgery in 16% (n = 22) of initially phakic eyes, redetachment in 13% (n = 21), and need for filtering surgery in 6% (n = 10). Logistic regression analysis revealed macula status (
P
= .003) and progression to filtering surgery (
P
= .001) as significant factors predicting visual outcome at 1-year follow-up.

CONCLUSION:
MT-PFO tamponade and upright head positioning may be efficacious for inferior retinal detachment repair in patients unable to assume face-down postoperative positioning. Anatomic and visual outcomes are similar to previously described reattachment procedures. A characteristic granulomatous inflammatory reaction presents in some patients, but does not appear to leave long-term visual or anatomic sequelae. Persistent IOP elevation and progression to filtering surgery may occur in a small percentage of patients and portends a worse visual outcome.
Arcuate Retinotomy for the Repair of Large Macular Holes
Authors: Charles Steve , Randolph John C. , Neekhra Aneesh , Salisbury Charles D. , Littlejohn Nathan , Calzada Jorge I. 
Published: January 2013

BACKGROUND AND OBJECTIVE:
To present a case series to elucidate a novel technique that involves the creation of an arcuate retinotomy in the treatment of large macular holes after failed primary repair.

PATIENTS AND METHODS:
retrospective chart review. Six eyes (six patients) with large macular holes, all of which had failed primary repair, underwent 25 gauge pars plana vitrectomy revision coupled with full thickness arcuate retinotomy temporal to the macular hole and fluid-gas exchange. The main outcome measure was anatomic macular hole closure based on optical coherence tomography (OCT), with visual acuity and visual field evaluation as secondary outcome measures.

RESULTS:
Five of the six patients (83%) had successful hole closure with three of the six patients (50%) exhibiting improvement in visual acuity.

CONCLUSION:
Arcuate retinotomy is a new approach that may aide in the repair of large macular holes not otherwise amenable to closure with traditional techniques.
Surgical Treatment of an Exudative Retinal Detachment Associated With a Giant Retinal Pigment Epithelial Tear
Authors: Desai Uday R. , Kumar Nitin 
Published: January 2013

After cataract surgery, a 69-year-old man presented with hypotony and choroidal effusion followed by retinal pigment epithelium tear and exudative detachment of the retina. Vitrectomy with fluid-air exchange successfully led to reattachment of all layers.
To the authors’ knowledge, this is the first reported case of successful surgical management of exudative detachment secondary to retinal pigment epithelium tears.
Non-target Gelechiidae and Noctuidae attraction toAroga trialbamaculella(Lepidoptera: Gelechiidae) pheromone-based trapping systems
Authors: Kelly Jillian A. , Avery Trevor S. , Stewart Donald T. , Cutler Christopher G. , Gaul Sonia O. , MacKenzie Kenna E. , Hillier N. Kirk 
Published: January 2013

AbstractCucullia umbraticaLinnaeus (Lepidoptera: Noctuidae),Agnippe prunifoliellaChambers (Lepidoptera: Gelechiidae), andBryotropha plantariellaTengstrom (Lepidoptera: Gelechiidae), were significant bycatch in pheromone-based trapping systems for red-striped fireworm,Aroga trialbamaculellaChambers (Lepidoptera: Gelechiidae), in Nova Scotia, Canada.Cucullia umbraticais a European introduced species and a new macrolepidopteran recorded in continental Canada. The only previous record of this moth in North America was from the Magdalen Islands (Québec, Canada). Potential attractants forB. plantariella,A. prunifoliella, andC. umbraticaare a result of this bycatch investigation.
Tim-3/Galectin-9 Regulate the Homeostasis of Hepatic NKT Cells in a Murine Model of Nonalcoholic Fatty Liver Disease
Authors: Tang Zhao-Hui , Liang Shuwen , Potter James , Jiang Xuan , Mao Hai-Quan , Li Zhiping 
Published: January 2013

Abstract
T cell Ig and mucin domain (Tim)-3 is well known to interact with its natural ligand, Galectin-9 (Gal-9), to regulate T cell function. However, little is known about the function of Tim-3/Gal-9 signaling in the pathogenesis of nonalcoholic fatty liver disease (NAFLD) mediated by hepatic NKT cells that also express Tim-3. In the current study, we define the role and the mechanism of Tim-3/Gal-9 signaling in hepatic NKT cell regulation in a mouse model of diet-induced NAFLD. Adult male wild-type or CD1d knockout C57BL/6 mice were fed a high-fat diet to induce steatosis. Some of the mice also received one or a combination of Gal-9, anti–IL-15R/IL-15 mAb, rIL-15, α-galactosylceramide, and multilamellar liposomes containing Cl2MDP. The expression of Tim-3 and various markers reflecting cell proliferation, activation, cytokine production, and apoptosis was analyzed. Liver histology, steatosis grade, and hepatic triglyceride content were also evaluated. In the liver, Tim-3+ NKT cells are in an activated state, and Gal-9 directly induces Tim-3+ NKT cell apoptosis and contributes to the depletion of NKT cells in diet-induced steatosis. However, Gal-9 also interacts with Tim-3–expressing Kupffer cells to induce secretion of IL-15, thus promoting NKT cell proliferation. Exogenous administration of Gal-9 significantly ameliorates diet-induced steatosis by modulating hepatic NKT cell function. In summary, the Tim-3/Gal-9–signaling pathway plays a critical role in the homeostasis of hepatic NKT cells through activation-induced apoptosis and secondary proliferation and, thus, contributes to the pathogenesis of NAFLD.
Evaluation of Corneal Elevation in Eyes with Subclinical Keratoconus and Keratoconus using Galilei Double Scheimpflug Analyzer
Authors: Jafarinasab Mohammad Reza , Feizi Sepehr , Karimian Farid , Hasanpour Hossein 
Published: January 2013

Purpose TO measure corneal elevations in eyes with subclinical keratoconus and those with keratoconus using the Galilei Scheimpflug analyzer and to determine the optimal corneal elevation cutoff points to maximize sensitivity and specificity in discriminating keratoconus and subclinical keratoconus from normal corneas. Methods A total of 136 normal eyes, 23 eyes with subclinical keratoconus, and 51 eyes with keratoconus were enrolled. Maximum anterior and posterior corneal elevation was measured in the central 3-, 5-, and 7-mm zones using the Galilei double Scheimpflug camera. Receiver operating characteristic curves were used to compare the sensitivity and specificity of the measured parameters and to identify optimal cutoff points for discriminating keratoconus and subclinical keratoconus from normal corneas. Results Mean anterior and posterior corneal elevations in all zones were statistically higher in keratoconus and subclinical keratoconus versus normal corneas. The posterior elevation measurement in the 3-mm zone had the strongest power to distinguish keratoconus from normal. The corresponding figure for the 7-mm zone, however, had the strongest power to distinguish eyes with subclinical keratoconus (area under the curve, 0.98 and 0.92, respectively). Optimal cutoff point for posterior elevation in the 3-mm zone was 18.5 μm for keratoconus (sensitivity, 92%; specificity, 95%). The corresponding figure in the 7-mm zone was 50.5 μm for subclinical keratoconus (sensitivity, 79.9%; specificity, 94.0%). Conclusions Anterior and posterior elevations measured by the Galilei analyzer in the 3-mm zone can effectively discriminate keratoconus from normal corneas. These measurements in the 7-mm zone can be considered to distinguish subclinical keratoconus.
Oficina acadêmica: bases curriculares e Medicina de Família e Comunidade
Authors: Calixto Phelipe Antônio , Bandina Celice , Oliveira Haniel Caetano de , Assis Filho Hermano Lúcio Gomes de , Matos Gustavo Faria de , César Camillo de Alcântara , Damasceno Adriano Aparecido Correia , Souza Neto Aureliano Inácio de , Oliveira Daniel Camilo de , Pereira Giovanna de Faria Alvim , Rocha Luana Bandeira , Moraes Matheus Bueno de , Ishisaki Nathália Lie , Melo Rafael César , Nicolau Theara de Castro 
Published: January 2013

De acordo com as Novas Diretrizes Curriculares Nacionais da Graduação Médica (NDCN) e sua orientação para uma postura crítica e reflexiva do acadêmico realizou-se a oficina “Bases curriculares e Medicina de Família e Comunidade” durante o IV Congresso Mineiro de Medicina de Família e Comunidade (IVCMMFC), em Belo Horizonte - MG, 12 de junho de 2009. A oficina tratou sobre a inserção da especialidade, Medicina de Família e Comunidade (MFC), na graduação, discutindo os métodos de ensino médico: Aprendizado baseado em problematização (PBL), método integrado de ensino e método tradicional Flexneriano. A oficina foi dividida em três momentos. Primeiramente, foi proposta adequação de algumas definições da literatura médica: Atenção Primária à Saúde, Médico generalista, Médico sanitarista, Especialista em Clínica Médica e Médico de Família e Comunidade. Após, foram discutidas as Novas diretrizes curriculares; o Relatório Flexner e sua influência nos modelos de ensino existentes (tradicional, problematizado e integrado), o momento oportuno para inserção da MFC na graduação e qual método de ensino utilizar. O tema do preconceito contra a especialidade surgiu nas discussões, assim como adequação da MFC e níveis de serviço (primário, secundário e terciário) e como valorizar a especialidade sem ¨super-especializar¨ o estudante. As conclusões levantadas na oficina foram descritas neste documento e apresentadas em plenária ao final do congresso.
Consumo de bebidas alcoólicas entre trabalhadores de uma unidade de Saúde da Família em Vitória, Espírito Santo, Brasil
Authors: Fontenelle Leonardo Ferreira 
Published: January 2013

Objetivo: Descrever o consumo de bebidas alcoólicas por trabalhadores da Atenção Primária à Saúde (APS). Métodos: Em dezembro de 2011 e fevereiro de 2012 realizou-se um levantamento anônimo com trabalhadores da APS numa unidade de Saúde da Família em Vitória (ES), através de questionário autoadministrado, com questões sobre frequência, quantidade usual e consumo em binge extraídas de um levantamento nacional. Foram obtidos ainda dados sociodemográficos e ocupacionais. Resultados: Dentre os 59 trabalhadores elegíveis, 53 (90%) participaram do levantamento. Ninguém relatou consumo muito frequente (5 dias ou mais por semana), mas 60% (32/53) relataram pelo menos um episódio de consumo nos últimos 12 meses. 76% (39/51; porém, 2 não responderam) relataram consumir usualmente 2 doses ou menos por dia de consumo. O consumo em binge foi relatado por 51% (27) de todos os 53 trabalhadores, ou seja, 84% dos 32 que consomem bebidas alcoólicas. Os trabalhadores de nível superior tiveram a menor prevalência de abstinência (19%; 3/16) e a menor proporção de consumo em binge entre os que consomem bebidas alcoólicas (69%; 9/13). Conclusões: Os trabalhadores dessa unidade de Saúde da Família apresentaram um consumo usualmente moderado de bebidas alcoólicas, mas a maioria consumiu em binge alguma vez nos últimos 12 meses. É necessário estudar no Brasil a relação entre o padrão de consumo de bebidas alcoólicas pelo trabalhador da APS e seu papel na detecção do uso problemático de álcool.
Avaliação de um programa de formação baseado no Mentoring para aquisição de habilidades em pequena cirurgia num centro de saúde urbano em Jaén, Andaluzia, Espanha
Authors: Perez-Milena Alejandro , Simao-Aiex Leticia , Ramirez-Picó Maria Araceli , Juárez-Jimenez Maria Villa 
Published: January 2013

Objetivos: Avaliar a implantação de um programa de tutoria em habilidades para a pequena cirurgia em um centro de saúde urbano. Desenho e métodos: Estudo descritivo transversal numa zona básica de saúde urbana composta por 16000 habitantes. Recolhemos todas as intervenções cirúrgicas realizadas durante os anos de 2009, 2010 e 2011. Estas foram divididas em dois grupos. Um primeiro grupo que compreende aquelas intervenções que foram autorizadas por um médico com experiência, e outro onde encontramos as não tutoradas. Também foram considerados os tipos de intervenção, existência de consentimento informado e o envio de amostras a anatomia patológica. Resultados: Foram realizadas um total de 363 intervenções (101 em 2009, 114 em 2010 e 148 em 2011), 45% autorizadas, sem encontrar diferenças por ano de realização nem por tipo de intervenção (59% extirpação de verrugas, 25% infiltrações, 7% quistos epidérmicos). Participaram da proposta, principalmente médicos residentes (96%), seguidos de médicos de família (62%) e por último a equipe de enfermagem (29%). Um maior número de peças cirúrgicas foram enviadas a anatomia patológica nos atos cirúrgicos tutorados (83% vs 62%, p < 0.05 test c²) assim como, houve um melhor preenchimento do consentimento informado. Conclusões: O sistema de formação em habilidades por mentoring em “Pequena Cirurgia” implicou progressivamente no restante de profissionais do Centro de Saúde, aumentou a quantidade de atos cirúrgicos realizados e melhorou a qualidade do programa. Aproveitar as habilidades dos profissionais que trabalham em Atenção Primária à Saúde (APS) para formar os colegas, pode atuar como catalizador para aumentar a capacidade de resposta e inovação.
Factors Affecting Morbidity and Mortality in Patients Who Underwent Emergency Operation for Incarcerated Abdominal Wall Hernia
Authors: Gul Mesut , Aliosmanoglu Ibrahim , Kapan Murat , Onder Akin , Taskesen Fatih , Arikanoglu Zulfu , Tacyildiz Ibrahim 
Published: January 2013

Abstract
Patients with incarcerated abdominal wall hernias (AWHs) are often encountered in emergency care units. Despite advances in anesthesia, antisepsis, antibiotic therapy, and fluid therapy, the morbidity and mortality rates for these patients remain high. Between 2006 and 2011, we retrospectively analyzed the cases of 131 patients who underwent emergency surgery for incarcerated abdominal wall hernias. Of these, there were 70 women (53.4%) and 61 men (46.6%) with an average age of 63.3 ± 17.4 years (range, 17–91 years). Morbidity was observed in 28 patients (21.4%), and the mortality rate was 2.3%. Intestinal resection, presence of concomitant disease, and general anesthesia were the independent variants that affected morbidity of patients with incarcerated abdominal wall hernias.
A Case of Successful Conservative Treatment for Chylous Ascites After Living-Donor Liver Transplantation
Authors: Shiba Hiroaki , Wakiyama Shigeki , Gocho Takeshi , Ishida Yuichi , Misawa Takeyuki , Yanaga Katsuhiko 
Published: January 2013

AbstractA 46-year-old man underwent living-donor liver transplantation and splenectomy for primary biliary cirrhosis. On postoperative day 22, cloudiness of ascites increased, and triglyceride concentration in ascites was as high as 1046 mg/dL. With a diagnosis of chylous ascites, total parenteral nutrition was started. Nine days after starting total parenteral nutrition, cloudiness of ascites decreased, and triglycerides in ascites decreased to 93 mg/dL. Oral intake was restarted, and the patient was discharged on postoperative day 46. Chylous ascites is a rare complication after living-donor liver transplantation for which total parenteral nutrition may be useful.
Left-Sided Sigmoid Diverticulitis Presenting as Right-Sided Thigh Abscess
Authors: Murphy Patrick Bates , Belliveau Paul 
Published: January 2013

Abstract
Acquired diverticular disease of the colon is very common in the North American population. Atypical presentations are usually due to complications and rarely the predominant complaint may be related to an associated fistula. Thigh abscesses due to colocutaneous fistula represent an uncommon complication of sigmoid diverticulitis. In rare cases, a thigh abscess may be the only symptom, but gas in the thigh should raise the index of suspicion for bowel pathology. We report the second known case of a left-sided sigmoid diverticulitis leading to an isolated right thigh abscess with no gastrointestinal symptoms.
Effect of Shorter Term of Intravenous Infusion for Reduction of Catheter-Related Bloodstream Infection After Gastrectomy
Authors: Kawamura Hideki , Tanioka Toshiro , Kuji Mariko , Shibuya Kazuaki , Takahashi Masahiro 
Published: January 2013

Abstract
After gastrectomy, a longer period of intravenous alimentation is required than for other digestive surgeries, portending a higher risk of catheter-related bloodstream infection (CRBSI). From assessment of CRBSI occurring between 2004 and 2007 (preintervention group), the duration of intravenous infusion between 2008 and 2010 (postintervention group) was changed to shorter-term (6-day) infusion. To verify the effect of changes in injection schedule on the incidence of CRBSI, the occurrence of CRBSI was studied comparatively among preintervention and postintervention cases, excluding cases requiring intravenous infusion preoperatively, and cases requiring long-term intravenous infusion postoperatively due to postoperative complications. The rate of CRBSI in the postintervention group (0%; 0 of 298) was significantly lower than that in the preintervention group (1.7%; 8 of 477; P = 0.026). There was no significant difference between preintervention and postintervention groups in postoperative complications. Six-day infusion decreased the incidence of CRBSI after gastrectomy significantly, without increasing postoperative complications.
Retained Foreign Body After Laser Ablation
Authors: Ren Shiyan , Liu Peng , Wang Wei , Yang Yuguan 
Published: January 2013

Abstract
Laser ablation for varicose veins is a common practice, and postoperative complications may happen. A retained foreign body could be left accidently in the treated leg. It is rarely reported in literature. We herein describe two cases of retained foreign body during the laser ablation for varicose veins. One patient with varicose veins received laser therapy 5 years earlier, and had experienced discomfort and pain. After investigation, an overlooked sheath fragment was removed surgically from the leg. Another patient with varicose veins had discomfort after laser ablation for 8 days, and has been asymptomatic after the removal of the retained foreign body in the leg. The essential preventive approach include to pinpoint the site of the tip of fiberoptic laser fiber and pull 1 to 2 cm of the sheath out of the patient, then withdrawal the fiberoptic fiber and sheath simultaneously. A white flash light in the trunk of the fiberoptic laser fiber is an important warning signal of an erroneous manipulation during the operation. The surgeon should routinely check the intact sheath and fiberoptic fiber after laser ablation. In conclusion, retained foreign body can be prevented by following some practical tips during laser ablation.
What Clinical Factors Affect Length of Transition to Psoriatic Arthritis in Patients With Psoriasis?
Authors: Cheemalavagu Shashank , Jin Yuxuan , Husni M. Elaine 
Published: June 2024

ObjectiveWe aimed to identify clinical and demographic features associated with the interval between psoriasis (PsO) and psoriatic arthritis (PsA).MethodsWe identified patients with PsO and PsA diagnoses from our tertiary care psoriatic disease biorepository: a longitudinal, real‐world database including clinical information and patient‐reported outcomes. We used a multivariable a zero‐inflated negative binomial model to evaluate several clinical and demographic features that may be associated with the time between PsO and PsA onset.ResultsA total of 384 patients were included, of whom 52.2% were female. The mean age of PsO onset was 31.5 years. Advanced age at PsO onset was associated with a shorter interval between PsO and PsA. Based on our model, patients with PsO onset at age 42.6 years (upper end of the interquartile range [IQR]) had a 62% shorter expected interval compared with patients with PsO onset at age 18.9 years (lower end of IQR) (P < 0.001) and were more likely to have concurrent (onset within 6 months) diagnoses (odds ratio 4.56; 95% confidence interval 2.9–7.17). Patients with a body mass index (BMI) of 34 compared with a BMI of 26 had a 10% shorter interval between PsO and PsA, which trended toward statistical significance (P = 0.053).ConclusionOur study demonstrated that patients with a diagnosis of PsO at an older age have a shorter interval between PsO and PsA diagnoses and are more likely to have concurrent diagnoses compared with patients with an onset of PsO at a younger age. These results suggest that patients with a later onset of PsO may benefit from earlier PsA screening.
Magnetic Resonance Imaging Topography of Bone Marrow Edema in the Sacroiliac Joint of Postpartum Women
Authors: Kiil Rosa Marie , Weber Ulrich , Jurik Anne Grethe 
Published: June 2024

ObjectiveA traditional monoplanar semicoronal and a biplanar magnetic resonance imaging (MRI) assessment method were used to compare the topographical distribution of postpartum strain‐related bone marrow edema (BME) at the sacroiliac joint (SIJ).MethodsThe presence and topographical location of SIJ BME were assessed independently by three readers in 71 women 12 months postpartum. A traditional monoplanar semicoronal and a biplanar BME evaluation by 8 (upper and lower) and 12 joint (upper, middle, and lower) regions, respectively, was performed with >4 weeks between the two assessments. Descriptive results were reported as mean ± SD and ranges, and interreader agreement by intraclass correlation coefficient (ICC).ResultsBy semicoronal assessment, 38 (53.5%) women had BME with a mean ± SD SPARCC score of 2.3 ± 4.0 (range 0–22; ICC 0.93, 95% confidence interval [CI] 0.92–0.94). Forty‐one (57.8%) had BME by biplanar assessment with a mean ± SD sum score of 2.9 ± 5.8 (range 0–32.7; ICC 0.89, 95% CI 0.88–0.91). By semicoronal assessment, the highest frequency and mean SPARCC scores were in the anterior upper regions of ilium (24%, mean 0.6) and sacrum (21%, mean 0.3) followed by the posterior upper sacral (20%, mean 0.4) and posterior lower iliac (20%, mean 0.3) regions. By biplanar assessment, the anterior middle joint regions had highest BME frequency and sum scores, sacral side (32%, mean 1.9) and iliac side (27%, mean 2.0), respectively; frequencies and sum scores were generally higher in the anterior compared to the posterior joint regions.ConclusionThe 12‐region biplanar assessment revealed a predominantly anterior middle location of postpartum SIJ BME whereas the 8‐region monoplanar approach did not demarcate distinct strain‐prone SIJ regions. Complementing traditional monoplanar semicoronal SIJ MRI evaluation by a semiaxial assessment may facilitate discrimination of strain‐related conditions from early axial spondyloarthritis.