bluuebunny/crossref_metadata_2025_split huggingface dataset:
Manipulation of Oxidation States on Phase Boundary via Surface Layer Modification for Enhanced Alkaline Hydrogen Electrocatalysis
Authors: Huang Huawei , Xu Liangliang , Zuo Shouwei , Song Lu , Zou Chen , García‐Melchor Max , Li Yang , Ren Yuafu , Rueping Magnus , Zhang Huabin 
Published: July 2024

AbstractIn alkaline water electrolysis and anion exchange membrane water electrolysis technologies, the hydrogen evolution reaction (HER) at the cathode is significantly constrained by a high energy barrier during the water dissociation step. This study employs a phase engineering strategy to construct heterostructures composed of crystalline Ni4W and amorphous WOx aiming to enhance catalytic performance in the HER under alkaline conditions. This work systematically modulates the oxidation states of W within the amorphous WOx of the heterostructure to adjust the electronic states of the phase boundary, the energy barriers associated with the water dissociation step, and the adsorption/desorption properties of intermediates during the alkaline HER process. The optimized catalyst, Ni4W/WOx‐2, with a quasi‐metallic state of W coordinated by a low oxygen content in amorphous WOx, demonstrates exceptional catalytic performance (22 mV@10 mA cm−2), outperforming commercial Pt/C (30 mV@10 mA cm−2). Furthermore, the operando X‐ray absorption spectroscopy analysis and theoretical calculations reveal that the optimized W atoms in amorphous WOx serve as active sites for water dissociation and the nearby Ni atoms in crystalline Ni4W facilitated the release of H2. These findings provide valuable insights into designing efficient heterostructured materials for energy conversion.
Extracting Geometry and Topology of Orange Pericarps for the Design of Bioinspired Energy Absorbing Materials
Authors: Fox Chelsea , Chen Kyle , Antonini Micaela , Magrini Tommaso , Daraio Chiara 
Published: July 2024

AbstractAs a result of evolution, many biological materials have developed irregular structures that lead to outstanding mechanical performances, like high stiffness‐to‐weight ratios and good energy absorption. However, reproducing these irregular biological structures in synthetic materials remains a complex design and fabrication challenge. Here, a bioinspired material design method is presented that characterizes the irregular structure as a network of building blocks, also known as tiles, and rules to connect them. Rather than replicating the biological structure one‐to‐one, synthetic materials are generated with the same distributions of tiles and connectivity rules as the biological material and it is shown that these equivalent materials have structure‐to‐property relationships similar to the biological ones. To demonstrate the method, the pericarp of the orange, a member of the citrus family known for its protective, energy‐absorbing capabilities is studied. Polymer samples are generated and characterized under quasistatic and dynamic compression and display spatially‐varying stiffness and good energy absorption, as seen in the biological materials. By quantifying which tiles and connectivity rules locally deform in response to loading, it is also determined how to spatially control the stiffness and energy absorption.
Rational Design of Earth‐Abundant Catalysts toward Sustainability
Authors: Guo Jinyang , Haghshenas Yousof , Jiao Yiran , Kumar Priyank , Yakobson Boris I. , Roy Ajit , Jiao Yan , Regenauer‐Lieb Klaus , Nguyen David , Xia Zhenhai 
Published: July 2024

AbstractCatalysis is crucial for clean energy, green chemistry, and environmental remediation, but traditional methods rely on expensive and scarce precious metals. This review addresses this challenge by highlighting the promise of earth‐abundant catalysts and the recent advancements in their rational design. Innovative strategies such as physics‐inspired descriptors, high‐throughput computational techniques, and artificial intelligence (AI)‐assisted design with machine learning (ML) are explored, moving beyond time‐consuming trial‐and‐error approaches. Additionally, biomimicry, inspired by efficient enzymes in nature, offers valuable insights. This review systematically analyses these design strategies, providing a roadmap for developing high‐performance catalysts from abundant elements. Clean energy applications (water splitting, fuel cells, batteries) and green chemistry (ammonia synthesis, CO2 reduction) are targeted while delving into the fundamental principles, biomimetic approaches, and current challenges in this field. The way to a more sustainable future is paved by overcoming catalyst scarcity through rational design.
Ring Finger Protein 217 Inhibits Ovarian Cancer Progression by Down‐Regulating HAX1 Expression
Authors: Zhou Lili , Liu Junbo , Zhou Min , Xu Lan 
Published: July 2024

AbstractRing finger protein 217 (RNF217) has been found to interact with the antiapoptotic protein HS‐1‐associated protein X‐1 (HAX‐1) in myeloid leukemia cells. However, the understanding of RNF217 in ovarian cancer progression remains limited. The relative expression of RNF217 is screened in ovarian cancer using the GEPIA database and calculated its correlation with MKI67, CCNB1, and CDK4. OVCAR‐3 and SK‐OV‐3 cells are transfected with RNF217‐overexpression plasmids. Cell‐counting kit‐8 assay is utilized to assess proliferation. Immunoprecipitation is performed to reveal the interaction between RNF217 and HAX‐1, and a cycloheximide chase assay is performed to analyze HAX‐1 degradation. The GEPIA database indicated down‐regulated expression of RNF217 in ovarian cancer, negatively correlated with MKI67 (R = ‐0.26, P = 1.8e‐09), CCNB1 (R = ‐0.37, P = 3.2e‐18), and CDK4 expression (R = ‐0.24, P = 3.4e‐08). RNF217 overexpression down‐regulated the relative expression of MKI67, CCNB1, and CDK4 in OVCAR‐3 and SK‐OV‐3 cells, resulting in diminished proliferation. In vivo studies using OVCAR‐3 and SK‐OV‐3 cell line‐derived xenograft models also showed that RNF217 overexpression reduced ovarian cancer volume and weight. Furthermore, RNF217 overexpression in SK‐OV‐3 cells inhibited the protein expression of HAX1 by reducing its stability. In conclusion, RNF217 inhibits ovarian cancer progression by down‐regulating HS‐1‐associated protein X‐1 expression.
Parity‐Frequency‐Space Elastic Spin Control of Wave Routing in Topological Phononic Circuits
Authors: Huang Yao , Yang Chenwen , Yuan Weitao , Zhang Yuxuan , Pan Yongdong , Yang Fan , Zhong Zheng , Zhao Jinfeng , Wright Oliver B. , Ren Jie 
Published: July 2024

AbstractTopological phononic cavities, such as ring resonators with topological whispering gallery modes (TWGMs), offer a flexible platform for the realization of robust phononic circuits. However, the chiral mechanism governing TWGMs and their selective routing in integrated phononic circuits remain unclear. This work reveals, both experimentally and theoretically, that at a phononic topological interface, the elastic spin texture is intricately linked to, and can be explained through a knowledge of, the phonon eigenmodes inside each unit cell. Furthermore, for paired, counterpropagating TWGMs based on such interfaces in a waveguide resonator, this study demonstrates that the elastic spin exhibits locking at discrete frequencies. Backed up by theory, experiments on kHz TWGMs in thin honeycomb‐lattice aluminum plates bored with clover‐leaf shaped holes show that together with this spin‐texture related angular‐momentum locking mechanism at a single topological interface, there are triplicate parity‐frequency‐space selective wave routing mechanisms. In the future, these mechanisms can be harnessed for the versatile manipulation of elastic‐spin based routing in phononic topological insulators.
Functional Separators for Modulating Li‐Ion Flux Toward Uniform Li Deposition: A Review
Authors: Ji Yuanpeng , Yang Chunhui , Han Jiecai , He Weidong 
Published: July 2024

AbstractHomogeneous Li‐ion flux is a significant precondition of uniform Li‐ion deposition in Li metal batteries (LMBs). Numerous methodologies have been presented for homogenizing Li‐ion flux before Li deposition based on the features of Li‐ion deposition. Separators that provide Li‐ion transfer channels and are directly exposed to Li metal anodes have attracted rising attention for their role in guiding regular Li‐ion distribution. More novel functional separators have been proposed aiming to achieve dendrite‐free deposition. Herein, the factors and strategies that regulate Li‐ion distribution through functional separators toward LMBs are concentrated on. The current mechanisms of Li‐ion flux regulation by functional separators are first highlighted, including physical properties, interactions with the electrolyte, and modification of the solid‐state electrolyte interphase. According to these mechanisms, functional separator strategies for regulating Li‐ion flux are divided into three methodologies, and typical examples are introduced. Finally, current limitations and suggestions for future functional separator studies are presented, aiming to inspire engaged researchers and newcomers to trigger more exciting works in this area.
Beyond Cation Disorder: Site Symmetry‐Tuned Optoelectronic Properties of the Ternary Nitride Photoabsorber ZrTaN3
Authors: Sirotti Elise , Wagner Laura I. , Jiang Chang‐Ming , Eichhorn Johanna , Munnik Frans , Streibel Verena , Schilcher Maximilian J. , März Benjamin , Hegner Franziska S. , Kuhl Matthias , Höldrich Theresa , Müller‐Caspary Knut , Egger David A. , Sharp Ian D. 
Published: July 2024

AbstractTernary nitrides are rapidly emerging as promising compounds for optoelectronic and energy conversion applications, yet comparatively little of this vast composition space has been explored. Furthermore, the crystal structures of these compounds can exhibit a significant amount of disorder, the consequences of which are not yet well understood. Here, the deposition of bixbyite‐type ZrTaN3 thin films is demonstrated by reactive magnetron co‐sputtering and observed semiconducting character, with a strong optical absorption onset at 1.8 eV and significant photoactivity, with prospective application as functional photoanodes. It is found that Wyckoff‐site occupancy of cations is a critical factor in determining these beneficial optoelectronic properties. First‐principles calculations show that cation disorder leads to minor deviations in the total energy but modulates the bandgap by 0.5 eV, changing orbital hybridization of valence and conduction band states. In addition to demonstrating that ZrTaN3 is a promising visible light‐absorbing semiconductor and active photoanode material, the findings provide important insights regarding the role of cation ordering on the electronic structure of ternary semiconductors. In particular, it is shown that not only cation order, but also the cationic Wyckoff site occupancy has a substantial impact on key optoelectronic properties, which can guide future design and synthesis of advanced semiconductors.
Observational Constraints on the Parameters of Hořava–Lifshitz Gravity
Authors: Chaudhary Himanshu , Debnath Ujjal , Pacif Shibesh Kumar Jas , Molla Niyaz Uddin , Mustafa Ghulam , Maurya Sunil Kumar 
Published: July 2024

AbstractThis study investigates the accelerated cosmic expansion within the Hořava–Lifshitz (HL) Model. To constrain the cosmological parameters of this model, 17 Baryon Acoustic Oscillation points, 31 Cosmic Chronometer points, 40 Type Ia Supernovae points, 24 quasar Hubble diagram points, and 162 Gamma Ray Bursts points, along with the latest Hubble constant measurement (R22) are incorporated. is treated as a free parameter to extract and using late‐time datasets, aiming for optimal fitting values in each model. Treating as free improves precision, reduces bias, and enhances dataset compatibility. The obtained values of and are compared to the model, showing consistency with previous estimates from Planck and SDSS studies. The Akaike Information Criterion (AIC) and Bayesian Information Criterion (BIC) favor the Hořava–Lifshitz model, with the model having the lowest AIC. Additionally, and analyses are conducted to assess model preference. Validation using the reduced statistic indicates satisfactory fits for the Hořava–Lifshitz model, while recognizing as the preferred model. Extensions of the analysis warrant further investigation.
Dual‐Gradient Concentration Distribution in Sb−Cu Alloy Nanoarrays for Robust Sodium‐Ion Storage
Authors: Li Xinyan , Li Chao , Zhang Xin , Sun Jianguo , Liu Ximeng , Song Kepeng , Han Jiuhui , Wang John , Song Chen Jun 
Published: July 2024

AbstractAlloy‐type materials are attractive for anodes in sodium‐ion batteries (SIBs) owing to their high theoretical capacities and overall performance. However, the accumulation of stress/strain during repeated cycling results in electrode pulverization, leading to rapid capacity decay and eventual disintegration, thus hindering their practical applications. Herein, we report a 3D coral‐like Sb−Cu alloy nanoarray with gradient distribution of both elements. The array features a Sb‐rich bottom and a Cu‐rich top with increasing Sb and decreasing Cu concentrations from top to bottom. The former is the active component that provides the high capacity, whereas the latter serves as an inert additive that acts against volume variation. The gradual transition in composition within the electrode introduces a ladder‐type volume expansion effect, facilitating a smooth distribution and effective release of stress, thereby ensuring the wanted mechanical stability and structural integrity. The as‐developed nanoarray affords a high reversible capacity (460 mAh g−1 at 0.5 C), stable cycling (89 % retention over 120 cycles at 1.0 C), and superior rate capability (354 mAh g−1 at 10 C). The concentration dual‐gradient strategy paves a new pathway of designing alloy‐type materials forSIBs.
A Novel Approach for Autonomous Densely Spaced Acquisition of Buried Objects in Intertidal Environments—Field Examples From Avaldsnes, Norway
Authors: Olsen T. M. , Weibull W. , Escalona A. , Vivås A. S. 
Published: July 2024

ABSTRACTUnderwater archaeology relies on expensive and time‐consuming invasive methods for identifying and excavating objects buried in the seabed or identifying layers in shallow and intertidal environments. Especially shallow and intertidal environments are challenging due to locally high levels of sedimentation that offer good conditions for preserving organic material, that is, archaeological objects, in stabile and low‐oxygen environments. We present a system capable of dense (25 cm × 25 cm) survey coverage that enables nondestructive decimetre‐scale visualization of buried objects and sedimentary layers lying in the subsurface. The system comprises an autonomous surface vehicle (ASV) equipped with a single‐channel 2D Chirp sonar. A description of the vehicle design is presented, and results from five field tests demonstrate the ability of the system to collect high‐resolution acoustic data in a variety of shallow water environments. The system shows an example of the linearized zero offset reflectivity inversion dataset, visualizing a known buried shipwreck from the medieval period in Avaldsnes, Norway. The ASV system holds global implications as it can serve as a noninvasive first‐stage survey in sensitive heritage or archaeological areas. Areas where traditional methods are challenging, or invasive methods are dissuaded.
Isolation, discrimination, and feeling “constant guilt”: A mixed‐methods analysis of female physicians’ experience with fertility, family planning, and oncology careers
Authors: Marion Sarah , Dalwadi Shraddha M. , Kuczmarska‐Haas Aleksandra , Gillespie Erin F. , Ludwig Michelle S. , Holliday Emma B. , Thom Bridgette , Chino Fumiko , Lee Anna 
Published: July 2024

AbstractIntroductionFamily planning among female physicians is harmed by high risks of infertility, workload burden, poor family leave policies, and gender discrimination. Many women report feeling unsupported in the workplace, despite national policies to protect against unfair treatment.MethodsThis secondary analysis applied a modified version of the rigorous and accelerated data reduction technique to conduct a thematic analysis of comments to an open‐ended prompt. Comments were coded by multiple trained researchers then grouped and merged into illustrative themes via qualitative techniques.ResultsOf 1004 responses to the quantitative survey, 162 physicians completed the open‐ended prompt. Initial codes (n = 16) were combined into eight groups including, from which three overarching themes were identified. Institutional barriers were highlighted with comments discussing the increased need for parental leave, part‐time options and the concern for academic or professional punishment for being pregnant and/or having children. Departmental barriers were explored with comments grouped around codes of discrimination/negative culture and challenges with breastfeeding/pumping and childcare. Personal barriers were discussed in themes highlighting the difficulties that female physicians faced around the timing of family planning, challenges with reproductive health and assistance, and alternative circumstances and/or decisions against family planning.ConclusionBarriers to family planning in oncology exist across career domains from dysfunctional maternity leave to poor education on infertility risk. Solutions include improving institutional support, expanding parental leave, and general cultural change to improve awareness and promotion of family and career balance.
High‐throughput liquid chromatography‐vacuum differential mobility spectrometry‐mass spectrometry for the analysis of isomeric drugs of abuse in human urine
Authors: Cifuentes Girard Maria Fernanda , Knight Patrick , Hopfgartner Gérard 
Published: July 2024

AbstractThe use of differential mobility spectrometry at low pressure coupled to liquid chromatography‐mass spectrometry (LC‐vDMS‐MS) was investigated for the analysis of 13 drugs of abuse (DoA) including the following: cocaine, ecgonine methyl ester, cocaethylene, benzoylecgonine, norcocaine, tramadol, isomeric pairs of metabolites; O‐desmethyl‐cis‐tramadol and N‐desmethyl‐cis‐tramadol, and cannabinoids: Δ9‐tetrahydrocannabinol, Δ9‐tetrahydrocannabidiol, 11‐hydroxy‐Δ9‐tetrahydrocannabinol, 11‐nor‐9carboxy‐Δ9‐tetrahydrocannabinol, and 11‐nor‐9carboxy‐Δ9‐tetrahydrocannabinol glucuronide. Different parameters were optimized for isomeric separation, such as LC mobile phase composition (20%–100% methanol acetonitrile and isopropanol, flow rate: 8–100 μL/min) and DMS separation voltage. Methanol and acetonitrile significantly affected the compensation voltage of the analytes and improved DMS separation. A short trap/elute LC‐vDMS‐SIM/MS screening method of 1 min was developed to quantify 11 drugs of abuse (except THC/CBD), in addition to a 4‐min LC‐vDMS‐SIM/MS method to identify and quantify five cannabinoids including the isomers THC/CBD and three THC metabolites. THC is the principal psychoactive constituent of cannabis and is a controlled substance in comparison to its isomeric counterpart CBD; this highlights the importance and challenges to resolve these isomeric pairs by analytical techniques. The signal responses were linear over a concentration range of 0.005–10 μg/mL for the DoA and 1–1000 ng/mL for cannabinoids. The intraday and interday precision were better than 12.2% and accuracy better than 115%. Urine samples from subjects who tested positive for THC and/or cocaine during roadside drug testing were evaluated to assess the performance of the methods LC‐vDMS‐SIM/MS and LC‐MRM/MS. Results show that the developed LC‐vDMS‐SIM/MS method presents similar performance to LC‐MRM/MS with improved sample throughput.
Release of IL‐1β and IL‐18 in human primary bronchial epithelial cells exposed to cigarette smoke is independent of NLRP3
Authors: Dino Paola , Giuffrè Maria Rita , Buscetta Marco , Di Vincenzo Serena , La Mensa Agnese , Cristaldi Marta , Bucchieri Fabio , Lo Iacono Giovanna , Bertani Alessandro , Pace Elisabetta , Cipollina Chiara 
Published: July 2024

AbstractCigarette smoke (CS) is a major risk factor for chronic lung diseases and promotes activation of pattern recognition receptors in the bronchial epithelium. NOD‐like receptor family, pyrin domain‐containing 3 (NLRP3) is a pattern recognition receptor whose activation leads to caspase‐1 cleavage, maturation/release of IL‐1β and IL‐18, and eventually pyroptosis. Whether the NLRP3 inflammasome participates in CS‐induced inflammation in bronchial epithelial cells is still unclear. Herein, we evaluated the involvement of NLRP3 in CS‐induced inflammatory responses in human primary bronchial epithelial cells. To this purpose, human primary bronchial epithelial cells were stimulated with CS extracts (CSE) and lytic cell death, caspase activation (‐1, ‐8, ‐3/7), cytokine release (IL‐1β, IL‐18, and IL‐8), NLRP3, pro‐IL‐1β/pro‐IL‐18 mRNA, and protein expression were measured. The impact of inhibitors of NLRP3 (MCC950), caspases, and the effect of the antioxidant N‐acetyl cysteine were evaluated. We found that CSE increased pro‐IL‐1β expression and induced activation of caspase‐1 and release of IL‐1β and IL‐18. These events were independent of NLRP3 and we found that NLRP3 was not expressed. N‐acetyl cysteine reverted CSE‐induced caspase‐1 activation. Overall, our findings support that the bronchial epithelium may play a central role in the release of IL‐1 family cytokines independently of NLRP3 in the lungs of smokers.
Striking a balance: Exploring attention, attack accuracy and speed in fencing performance
Authors: Varesco Giorgio , Sarcher Aurélie , Doron Julie , Jubeau Marc 
Published: July 2024

AbstractIn fencing, it remains unclear whether practice enhances visual‐spatial attention allocation. We explored whether this ability is improved in fencers and if it is related to attack speed and accuracy. Twelve novices (<1 year of experience) and 12 trained epee fencers (18 ± 10 years of experience) visited the laboratory twice (familiarization and testing session). They performed a covert orienting of visuospatial attention test (COVAT) on a computer and an epee test, involving 30 trials of 3 shuttles followed by fast attack phases where the fencers quickly hit a target (randomly proposed out of 8). We measured COVAT reaction time, number of successful target hits, and execution time to hit in the fencing test. We found shorter COVAT reaction time for trained fencers (332 ± 24 ms) versus novices (367 ± 32 ms; p < 0.001). The number of hits was greater for trained fencers (22 ± 3) versus novices (16 ± 3; p < 0.001). ANCOVA showed a difference in execution time at the test (823 ± 73 ms vs. 913 ± 141 ms, p = 0.035). A relationship was found between hits and execution time and between execution time and COVAT reaction time for the trained group (r = 0.62, p = 0.03 and r = 0.70, p = 0.01, respectively) but not in the novice group (r = 0.11, p = 0.72 and r = 0.45, p = 0.14, respectively). Mediation analysis showed that the relationship between execution time and number of hits (ADE: p = 0.008) was not mediated by COVAT reaction time (ACME: p = 0.17). These results evidence the importance of visual‐spatial attention allocation in fencing and evidence differences between novices and trained fencers with important implications for talent development in the early career stage.