bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessment of the impact of observations at Nainital (India) and Comilla (Bangladesh) on the CH4 flux inversion
Authors: Belikov Dmitry A. , Patra Prabir K. , Terao Yukio , Naja Manish , Ahmed Md. Kawser , Saitoh Naoko 
Published: June 2024

AbstractMethane emission in South Asia is poorly understood due to a lack of observations, despite being a major contributor to methane emissions globally. We present the first results of atmospheric CH4 inversions using air samples collected weekly at Nainital, India (NTL), and Comilla, Bangladesh (CLA), in addition to surface background flask measurements by NOAA, CSIRO and AGAGE using the MIROC4-ACTM. Our simulations span from 2000 to 2020 (considering the fixed “edge” effect), but the main analysis period is 2013–2020, when both the NTL and CLA datasets are available. An additional flux uncertainty reduction of up to 40% was obtained (mainly in the northern part of the Indian subcontinent), which enhanced our confidence in flux estimation and reaffirmed the significance of observations at the NTL and CLA sites. Our estimated regional flux was 64.0 ± 4.7 Tg-CH4 yr−1 in South Asia for the period 2013–2020. We considered two combinations of a priori fluxes that represented different approaches for CH4 emission from rice fields and wetlands. By the inversion, the difference in emissions between these combinations was notably reduced due to the adjustment of the CH4 emission from the agriculture, oil and gas, and waste sectors. At the same time, the discrepancy in wetland emissions, approximately 8 Tg-CH4 yr−1, remained unchanged. In addition to adjusting the annual totals, the inclusion of NTL/CLA observations in the inversion analysis modified the seasonal cycle of total fluxes, possibly due to the agricultural sector. While the a priori fluxes consisted of a single peak in August, the a posteriori values indicated double peaks in May and September. These peaks are highly likely associated with field preparation for summer crops and emissions from rice fields during the heading stage (panicle formation). The newly incorporated sites primarily exhibit sensitivity to the Indo-Gangetic Plain subregion, while coverage in southern India remains limited. Expanding the observation network is necessary, with careful analysis of potential locations using back-trajectory methods for footprint evaluation.
A systematic review and bibliometric analysis of electric cooking: evolution, emerging trends, and future research directions for sustainable development
Authors: Odoi-Yorke Flavio 
Published: June 2024

AbstractMany developing countries, particularly in Africa and Asia, still widely use traditional cooking methods that rely on solid fuels such as wood and charcoal. These inefficient and polluting cooking practices have severe health impacts due to household air pollution, and they contribute to environmental degradation through deforestation and black carbon emissions. This has driven growing interest in cleaner and more sustainable cooking alternatives such as electric cooking (e-cooking), improved biomass cookstoves, biogas systems, and modern fuel stoves that can reduce emissions and fuel consumption while providing a safer cooking experience. E-cooking has emerged as a promising option to traditional cooking methods due to sustainability, health benefits, energy efficiency, convenience, safety, and potential for grid integration, making it a promising alternative to traditional cooking methods. This study followed the PRISMA guidelines for systematic reviews to assess the existing literature on e-cooking from 1993 to 2023. In addition, the biblioshiny package in R software was used to perform bibliometric analysis to identify key trends and evolutions. The results indicate that the United Kingdom, the United States, Japan, Australia, and China are the top five countries leading in e-cooking research. The study identified promising areas for future research, such as optimising solar e-cookers using artificial intelligence techniques, integrating internet of things and automation technologies in e-cookers, integrating e-cooking appliances into smart grid systems, examining effective behavioural change interventions, and exploring innovative business models. The study findings highlight the need for interdisciplinary collaboration among researchers, engineers, social scientists, and policymakers to address the technical, economic, socio-cultural, and environmental factors influencing the transition to e-cooking.
Description of patterns of ear and tail lesions during the grower-finisher period in a commercial pig farm
Authors: van Staaveren Nienke , Pessoa Joana , Boyle Laura Ann , Calderón Díaz Julia Adriana 
Published: June 2024

Abstract
Background
Ear and tail lesions are prevalent indicators of impaired welfare observed in pig production with different multifactorial causes. Understanding the progression of ear and tail lesions over time is important to implement preventative strategies on commercial pig farms. Therefore, this case study aimed to provide a detailed account of patterns of ear and tail lesions in pigs on a single commercial farm during the grower-finisher period.

Case presentation
A total of 1,676 12-week old pigs (n = 773 females and n = 903 males, all tail docked) were followed from arrival to the grower facilities until transferred to the finisher stage on a commercial pig farm in Ireland. Pigs were individually weighed and inspected for the severity of fresh ear and tail lesions (score 0–4) on transfer to the first grower (24.9 ± 5.33 kg, 12 weeks of age, n = 1,676 pigs), second grower (33.3 ± 7.04 kg, 14 weeks of age, n = 1,641 pigs), and finisher stage (60.2 ± 7.74 kg, 18 weeks of age, n = 1,626 pigs). Due to the low number of pigs with high scores, ear lesions were classified as no (score 0), mild (score 1), moderate (score 2) and severe (score ≥ 3) and tail lesions were classified as no (score 0), mild (score 1), and moderate-to-severe (score ≥ 2). Ear lesions were more prevalent than tail lesions at each inspection. There were approx. 19% of pigs with ear lesions at all three inspections but no pigs presented with tail lesions at all three inspections. When considering the specific severity categories, we observed 32 different ear lesion score combinations and 15 different tail lesion score combinations across the three inspections.

Conclusion
The high number of observed patterns of ear and tail lesions suggest large individual variability in lesion progression. Ear lesions were more of an issue than tail lesions and little is known about this health and welfare problem indicating that further research into causes and management strategies is needed.
The effect of smartphone addiction on adolescent health: the moderating effect of leisure physical activities
Authors: Zhang Rong , Jiang Qimeng , Cheng Meichao , Rhim Yong-Taek 
Published: June 2024

Abstract
Background
Smartphone addiction is a growing concern, especially among adolescents, due to its negative impact on health. This study examines how leisure physical activity influence this relationship.

Objective
This study aimed to investigate the relationship between smartphone addiction and adolescent health, examining the mediating role of loneliness and the moderating effect of leisure physical activity.

Methods
A survey of 1271 Chinese university students was conducted using the PAPS Health and Fitness Scale, Smartphone Addiction Scale, and Leisure Time Exercise Scale.

Results
Smartphone addiction negatively affects adolescent health. Loneliness mediates this relationship, while leisure physical activity moderates it. High levels of physical activity reduce the negative impact of loneliness on health (bsimple = −0.49, P < 0.001), whereas low levels enhance this impact (bsimple = −0.21, P < 0.001).

Conclusion
These research have practical implications for preventing and reducing smartphone addiction and offer a theoretical foundation for promoting healthier lifestyles among adolescents.
Antegrade embolization of varicocele with cyanoacrylate glue: a case report
Authors: Le Tat Thomas , Jost Raphaël , Hanotin Clément , Lucas Alexandre , Laouisset Liess , Hakime Antoine , Kuoch Viseth 
Published: June 2024

Abstract
Background
Varicocele embolization is an effective, minimally invasive treatment option, with a symptom improvement rate of around 90%. However, anatomical variations and post-embolization recurrences pose challenges to its efficacy. This article discusses the antegrade embolization technique as a viable alternative for cases in which retrograde embolization fails, offering a broader spectrum of treatment options for varicocele.

Case presentation
This case report details the treatment of a 27-year-old male with a left varicocele, diagnosed during infertility assessment, using an alternative embolization technique. Despite initial failed attempts at retrograde catheterization via the femoral vein, a direct inguinal puncture of the left testicular vein was successfully performed under ultrasound guidance. A mixture of Glubran® and Lipiodol® was used for embolization, achieving varicocele embolization without complications. The patient was discharged 2 hours post-procedure, with follow-up confirming the procedure’s effectiveness and safety.

Conclusion
This article introduces a less invasive, ultrasound-guided technique for varicocele embolization, presenting a viable alternative to surgery when conventional retrograde methods fail.

Graphical Abstract
Use of ketamine in Super Refractory Status Epilepticus: a systematic review
Authors: Adhikari Aayush , Yadav Sushil Kumar , Nepal Gaurav , Aryal Roshan , Baral Pratik , Neupane Peter , Paudel Aadesh , Pantha Barsha , Acharya Sulav , Shrestha Gentle Sunder , Khadayat Ramesh 
Published: June 2024

Abstract
Objective
This review specifically investigates ketamine’s role in SRSE management.

Methods
PubMed, EMBASE, and Google Scholar databases were searched from inception to May 1st, 2023, for English-language literature. Inclusion criteria encompassed studies on SRSE in humans of all ages and genders treated with ketamine.

Results
In this systematic review encompassing 19 studies with 336 participants, age ranged from 9 months to 86 years. Infections, anoxia, and metabolic issues emerged as the common causes of SRSE, while some cases had unknown origins, termed as NORSE (New Onset RSE) or FIRESs (Febrile Infection-Related Epilepsy Syndrome). Most studies categorized SRSE cases into convulsive (N = 105) and non-convulsive (N = 197). Ketamine was used after failed antiepileptics and anesthetics in 17 studies, while in others, it was a first or second line of treatment. Dosages varied from 0.5 mg/kg (bolus) and 0.2-15 mg/kg/hour (maintenance) in adults and 1-3 mg/kg (bolus) and 0.5-3 mg/kg/hour (maintenance) in pediatrics, lasting one to 30 days. Ketamine was concurrently used with other drugs in 40–100% of cases, most frequently propofol and midazolam. Seizure resolution rate varied from 53.3 to 91% and 40–100% in larger (N = 42–68) and smaller case series (N = 5–20) respectively. Seizure resolution occurred in every case of case report except in one in which the patient died. Burst suppression in EEG was reported in 12 patients from two case series and two case reports. Recurrence was reported in 11 patients from five studies. The reported all-cause mortality varied from 38.8 to 59.5% and 0-36.4% in larger and smaller case series., unrelated directly to ketamine dosage or duration.

Significance
Ketamine demonstrates safety and effectiveness in SRSE, offering advantages over GABAergic drugs by acting on NMDA receptors, providing neuroprotection, and reducing vasopressor requirement.
American College of Surgeons National Surgical Quality Improvement Program Surgical Risk Calculator as a Predictor of Postoperative Outcomes After Adult Spinal Deformity Surgery: A Retrospective Cohort Analysis
Authors: Im Justin , Soliman Mohamed A. R. , Aguirre Alexander O. , Quiceno Esteban , Burns Evan , Khan Ali M. A. , Kuo Cathleen C. , Baig Rehman A. , Khan Asham , Hess Ryan M. , Pollina John , Mullin Jeffrey P. 
Published: June 2024

BACKGROUND AND OBJECTIVES:
In recent years, there has been an outpouring of scoring systems that were built to predict outcomes after various surgical procedures; however, research validating these studies in spinal surgery is quite limited. In this study, we evaluated the predictability of the American College of Surgeons National Surgical Quality Improvement Program Surgical Risk Calculator (ACS NSQIP SRC) for various postoperative outcomes after spinal deformity surgery.

METHODS:
A retrospective chart review was conducted to identify patients who underwent spinal deformity surgery at our hospital between January 1, 2014, and December 31, 2022. Demographic and clinical data necessary to use the ACS NSQIP SRC and postoperative outcomes were collected for these patients. Predictability was analyzed using the area under the curve (AUC) of receiver operating characteristic curves and Brier scores.

RESULTS:
Among the 159 study patients, the mean age was 64.5 ± 9.5 years, mean body mass index was 31.9 ± 6.6, and 95 (59.7%) patients were women. The outcome most accurately predicted by the ACS NSQIP SRC was postoperative pneumonia (observed = 5.0% vs predicted = 3.2%, AUC = 0.75, Brier score = 0.05), but its predictability still fell below the acceptable threshold. Other outcomes that were underpredicted by the ACS NSQIP SRC were readmission within 30 days (observed = 13.8% vs predicted = 9.0%, AUC = 0.63, Brier score = 0.12), rate of discharge to nursing home or rehabilitation facilities (observed = 56.0% vs predicted = 46.6%, AUC = 0.59, Brier = 0.26), reoperation (observed 11.9% vs predicted 5.4%, AUC = 0.60, Brier = 0.11), surgical site infection (observed 9.4% vs predicted 3.5%, AUC = 0.61, Brier = 0.05), and any complication (observed 33.3% vs 19%, AUC = 0.65, Brier = 0.23). Predicted and observed length of stay were not significantly associated (β = 0.132, P = .47).

CONCLUSION:
The ACS NSQIP SRC is a poor predictor of outcomes after spinal deformity surgery.
Hook Fixation at Uppermost Instrumented Vertebra +1 Reduced Proximal Junctional Failure in Adult Patients With Spinal Deformity Having Achieved Optimal Deformity Correction by Sagittal Age-Adjusted Score
Authors: Park Se-Jun , Park Jin-Sung , Kang Dong-Ho , Kim Hyun-Jun , Lee Chong-Suh 
Published: June 2024

BACKGROUND AND OBJECTIVES:
Appropriate correction relative to the age-adjusted sagittal alignment target reduces the proximal junctional failure (PJF) risk. Nonetheless, a considerable number of patients suffer from PJF despite optimal correction. The aim of this study was to identify the risk factors of PJF that occurs despite optimal correction relative to the sagittal age-adjusted score (SAAS) in adult spinal deformity surgery.

METHODS:
Patients aged 60 years or older with adult spinal deformity who underwent ≥5-level fusion to the sacrum were initially screened. Among them, only patients who achieved optimal sagittal correction relative to the SAAS were included in the study. Optimal correction was defined as the SAAS point between −1 and +1. Various clinical and radiographic factors were compared between the PJF and no PJF groups and were further evaluated using multivariate analysis.

RESULTS:
The final study cohort comprised 127 patients. The mean age was 67 years, and there were 111 women (87.4%). A mean of total fusion length was 7.2. PJF occurred in 42 patients (33.1%), while 85 patients (66.9%) did not develop PJF. Multivariate analysis showed that a high body mass index (odds ratio [OR] = 1.153, 95% CI = 1.027-1.295, P = .016), a higher lordosis distribution index (LDI) (OR = 1.024, 95% CI = 1.003-1.045, P = .022), and no use of hook fixation (OR = 9.708, 95% CI = 1.121-76.923, P = .032) were significant risk factors of PJF development. In the receiver operating characteristic curve analysis, the cutoff value for the LDI was calculated as 61.0% (area under the curve = 0.790, P < .001).

CONCLUSION:
PJF developed in a considerable portion of patients despite optimal correction relative to the age-adjusted alignment. The risk factors of PJF in this patient group were high body mass index, high LDI exceeding 61%, and no use of hook fixation. PJF could be further decreased by properly managing these risk factors along with optimal sagittal correction.
Deep Learning of Transition Probability Densities for Stochastic Asset Models with Applications in Option Pricing
Authors: Su Haozhe , Tretyakov M. V. , Newton David P. 
Published: June 2024

Transition probability density functions (TPDFs) are fundamental to computational finance, including option pricing and hedging. Advancing recent work in deep learning, we develop novel neural TPDF generators through solving backward Kolmogorov equations in parametric space for cumulative probability functions. The generators are ultra-fast, very accurate and can be trained for any asset model described by stochastic differential equations. These are “single solve,” so they do not require retraining when parameters of the stochastic model are changed (e.g., recalibration of volatility). Once trained, the neural TDPF generators can be transferred to less powerful computers where they can be used for e.g. option pricing at speeds as fast as if the TPDF were known in a closed form. We illustrate the computational efficiency of the proposed neural approximations of TPDFs by inserting them into numerical option pricing methods. We demonstrate a wide range of applications including the Black-Scholes-Merton model, the standard Heston model, the SABR model, and jump-diffusion models. These numerical experiments confirm the ultra-fast speed and high accuracy of the developed neural TPDF generators. This paper was accepted by Kay Giesecke, finance. Funding: H. Su received research funding support from Nottingham Business School at Nottingham Trent University. M. V. Tretyakov was supported by the Engineering and Physical Sciences Research Council [Grant EP/X022617/1]. D. P. Newton received research funding support from the School of Management at Bath University. Supplemental Material: The online appendices and data files are available at https://doi.org/10.1287/mnsc.2022.01448 .
Knowledge economics and the demand for higher education
Authors: Kutrzeba Franciszek Filip 
Published: June 2024

ObjectivesTo demonstrate that the changes in demand for higher education in Poland are partially caused due to the changes in consumer preferences. To examine the relationship between the supply-demand for higher education and massive open online courses. To present a novel approach to understanding the nature of the knowledge market and to demonstrate, that knowledge is misleadingly called to be non-rival and non-excludable.Material and methodsThe study employs the supply-demand model for the examination of the declined demand for higher education in Poland. It is a conceptualized approach that examines the possibility of new determinants behind the fore-mentioned trend.ResultsThe appearance of a cheap and highly accessible form of knowledge acquisition, the massive open online courses, should have impact on the supply-demand quality of the knowledge produced and consumed. The results suggest, that the appearance of a cheaper substitute to scientific knowledge leads to a shift in consumers' preferences.ConclusionsA decline in the enrollment rates in Poland and other high-income countries have taken place due to demographic shifts but possibly also to other factors such as the appearance of a cheaper substitute to knowledge offered by the Academia. This substitution effect is driven by technological advancements and cultural shifts towards free and open-source knowledge production. The knowledge market is described as volatile and characterized by imperfect competition. Technological advancements have led to an oversupply of knowledge, causing prices to decrease and demand to increase. The market for knowledge is transitioning from an oligopoly with high barriers to entry to a more cooperative and competitive environment (coopetition), where various forms of knowledge production coexist and interact.
Is the rise in childhood obesity rates leading to an increase in hospitalizations due to dengue?
Authors: Jeewandara Chandima , Karunananda Maneshka Vindesh , Fernando Suranga , Danasekara Saubhagya , Jayakody Gamini , Arulkumaran Segarajasingam , Samaraweera Nayana Yasindu , Kumarawansha Sarathchandra , Sivaganesh Subramaniyam , Amarasinghe Priyadarshanie Geethika , Jayasinghe Chintha , Wijesekara Dilini , Marasinghe Manonath Bandara , Mambulage Udari , Wijayatilake Helanka , Senevirathne Kasun , Bandara Aththidayage Don Priyantha , Gallage Chandana Pushpalal , Colambage Nilu Ranmali , Udayasiri Ampe Arachchige Thilak , Lokumarambage Tharaka , Upasena Yasanayakalage , Weerasooriya Wickramasinghe Pathiranalage Kasun Paramee ,   Seroprevalence study group, Ogg Graham S. , Malavige Gathsaurie Neelika 
Published: June 2024

Background
Obesity and diabetes are known risk factors for severe dengue. Therefore, we sought to investigate the association of obesity with increased risk of hospitalization, as there is limited information.

Methods and findings
Children aged 10 to 18 years (n = 4782), were recruited from 9 districts in Sri Lanka using a stratified multi-stage cluster sampling method. Details of previous admissions to hospital due to dengue and anthropometric measurements were recorded and seropositivity rates for dengue were assessed. The body mass index (BMI) centile in children aged 10 to 18, was derived by plotting the values on the WHO BMI-for-age growth charts, to acquire the percentile ranking.

Results
Although the dengue seropositivity rates were similar in children of the different BMI centiles, 12/66 (18.2%) seropositive children with a BMI centile >97th, had been hospitalized for dengue, compared to 103/1086 (9.48%) of children with a BMI centile of <97th. The logistic regression model suggested that BMI centiles 50th to 85th (OR = 1.06, 95% CI, 1.00 to 1.11, p = 0.048) and BMI centile of >97th (OR 2.33, 95% CI, 1.47 to 3.67, p = 0.0003) was significantly associated with hospitalization when compared to children in other BMI categories.

Conclusions
Obesity appears to be associated with an increased risk of hospitalization in dengue, which should be further investigated in longitudinal prospective studies. With the increase in obesity in many countries, it would be important to create awareness regarding obesity and risk of severe disease and hospitalization in dengue.