bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Minireview on Porphyrin and Phthalocyanine Based Catalysts for Electrocatalytic Synthesis of Ammonia
Authors: Xie Lisi , Wang Yabo , Kong Qingquan , Cao Rui 
Published: July 2024

AbstractAmmonia (NH3) is an important raw material in the chemical industry, but the synthesis of NH3 by the traditional Haber‐Bosch process will increase the carbon footprint. Therefore, it is necessary to develop sustainable routes for NH3 production. New NH3 production schemes, including nitrogen reduction (N2RR), nitrite reduction (NO2RR), and nitrate reduction (NO3RR), have been proposed. Porphyrins and phthalocyanines are macrocyclic compounds with a central metal ion coordinated with nitrogen. The metal centers in these catalysts play a crucial role in binding and activating nitrogen, nitrite, and nitrate. Their unique structure allows for effective electron transfer and catalytic activation in NH3 synthesis. Recently, metal porphyrin and phthalocyanine based catalysts have been demonstrated to be efficient in catalyzing N2RR, NO2RR, and NO3RR. Unfortunately, there is no review focusing on such macrocyclic catalysts for the electrocatalytic synthesis of NH3. In this review, we discuss the electrocatalytic reduction performances and summarize the key factors and reaction mechanisms that affect the catalytic performance of metal porphyrin and phthalocyanine based catalyst systems. This review helps to design more effective new electrocatalysts for NH3 synthesis.
Photothermal Oxidation of Volatile Organic Compounds Over Co3O4‐Based Inverse Opal
Authors: Lai Jun‐an , Xu Jianheng , Wang Jiakun , Zhang Zeshu , Zhang Yibo , Wang Lu 
Published: July 2024

AbstractThe growing preference for photothermal catalysis stems from its minimal energy consumption and heightened catalytic efficacy. Nonetheless, material photon utilization efficiency is frequently hindered by catalyst structural design constraints and bandgap limitations. Herein, we present a Co3O4‐based inverse opal featuring a three‐dimensional ordered macroporous (3DOM‐Co3O4) architecture tailored for photothermal VOCs oxidation. The 3DOM‐Co3O4 exhibits superior catalytic performance in carbon monoxide oxidation, methane oxidation, and toluene oxidation, with a photothermal enhancement of more than 100 %. Further experimental and theoretical analyses reveal that the three‐dimensional periodic array of pores facilitates the slow photon effect, augmenting the light absorption capabilities of the catalyst. Thus, it generates more photoexcited electrons, promoting VOCs molecular activation. Additionally, the well‐ordered porous structure facilitates the diffusion of reactants and products, further accelerating the catalytic reaction. This work highlights promising prospects for leveraging inverse opals as an innovative strategy towards enhancing photothermal catalytic VOCs oxidization efficiency.
Robust estimation of loss‐based measures of model performance under covariate shift
Authors: Morrison Samantha , Gatsonis Constantine , Dahabreh Issa J. , Li Bing , Steingrimsson Jon A. 
Published: July 2024

AbstractWe present methods for estimating loss‐based measures of the performance of a prediction model in a target population that differs from the source population in which the model was developed, in settings where outcome and covariate data are available from the source population but only covariate data are available on a simple random sample from the target population. Prior work adjusting for differences between the two populations has used various weighting estimators with inverse odds or density ratio weights. Here, we develop more robust estimators for the target population risk (expected loss) that can be used with data‐adaptive (e.g., machine learning‐based) estimation of nuisance parameters. We examine the large‐sample properties of the estimators and evaluate finite‐sample performance in simulations. Last, we apply the methods to data from lung cancer screening using nationally representative data from the National Health and Nutrition Examination Survey (NHANES) and extend our methods to account for the complex survey design of the NHANES.
Polo‐like kinase 1 inhibition modulates urinary tract smooth muscle contraction and bladder cell transcriptional programs
Authors: Wang Xiaolong , Guo Linfa , Yisha Zuhaer , Gu Aodun , Liu Tongzu 
Published: July 2024

AbstractThe serine/threonine kinase polo‐like kinase 1 (PLK1) is a master regulator of cell proliferation and contraction, but its physiological role in the lower urinary tract is unknown. We utilized transcriptomic programs of human bladder smooth muscle cells (hBSMCs), 3D bladder spheroid viability assays, and human ureterovesical junction contractility measurements to elucidate the impacts of PLK1 inhibition. This work reveals PLK1 reduction with the selective inhibitor TAK‐960 (500 nM) suppresses high K+‐evoked contractions of human urinary smooth muscle ex vivo while decreasing urothelial cell viability. Transcriptomic analysis of hBSMCs treated with TAK‐960 shows modulation of cell cycle and contraction pathways, specifically through altered expression of Cys2/His2‐type zinc finger transcription factors. In bladder spheroids, PLK1 inhibition also suppresses smooth muscle contraction protein filamin. Taken together, these findings establish PLK1 is a critical governor of urinary smooth muscle contraction and urothelial proliferation with implications for lower urinary tract disorders. Targeting PLK1 pharmacologically may therefore offer therapeutic potential to ameliorate hypercontractility and aberrant growth. Further elucidation of PLK1 signaling networks promises new insights into pathogenesis and much needed treatment advances for debilitating urinary symptoms.
Effect of a High‐Fat Meal on the Pharmacokinetics of an Immediate Release Atogepant Tablet
Authors: Boinpally Ramesh R. , Trugman Joel M. 
Published: July 2024

AbstractAtogepant, an oral calcitonin gene‐related peptide receptor antagonist, is approved for the preventive treatment of migraine. A phase 1, open‐label, single‐dose, 2‐period crossover study evaluated the effect of a high‐fat meal on the pharmacokinetics and safety of atogepant in 20 healthy adults. Administration of atogepant 60 mg immediate‐release (IR) tablets under fed conditions reduced the area under the plasma concentration‐time curve (AUC) from 0 to time t and from 0 to time infinity by approximately 18% and reduced the maximum plasma concentration (Cmax) by 22%. The 90% confidence intervals for the geometric mean ratios of Cmax and AUC were not contained within the bioequivalence limits of 80%‐125%. There was no change in the median time to maximum plasma concentration in the fed versus fasted state. The incidence of treatment‐emergent adverse events (TEAEs) was similar between fed and fasted conditions. Four TEAEs were considered related to study intervention and were reported after participants received atogepant under fasted conditions (3 participants). A single‐dose atogepant 60 mg IR tablet was safe and tolerated under both fed and fasted states. Due to the wide effective dose range of 10‐60 mg/day for atogepant for the preventive treatment of migraine, the food effect on its pharmacokinetics is not considered clinically relevant.
Culturally Local Perspectives Are Imperative to Scientific Excellence and Health Equity in Eating Disorders Research: Commentary on Monocello et al. (2024)
Authors: Lheem Anne Jung , Becker Anne E. 
Published: July 2024

ABSTRACTThis commentary discusses a principal contribution of Monocello et al.'s paper presenting a cultural models approach to body fatness perceptions, which provides a rigorous and systematic means of identifying analytic categories that are locally meaningful, in contrast to categories derived from a solely universalizing perspective. In situating their work within an underrepresented population in eating disorders research—young men in South Korea—the authors step beyond the constraints of a universalizing, or etic, framework for probing how body dissatisfaction relates to eating disorder risk. The value of an alternative analytic framework, based on a culturally local, or emic, perspective on how bodies are perceived is demonstrated through the use of a cultural models approach exploring the relationship between culturally defined conceptualizations of body image and eating disorder risk. Understanding such relationships and the meanings attributed to the myriad aspects of body image through locally grounded frameworks provides an essential tool for investigators and clinicians to better understand the lived experience of body dissatisfaction and disordered eating, and also to inform more culturally salient approaches to diagnosis, treatment, and prevention. An emic approach that centers local perspectives and priorities also facilitates participation of communities underrepresented in research in knowledge production.
Habitual behavioural control moderates the relation between daily perceived stress and purging
Authors: Dougherty Elizabeth N. , Bottera Angeline R. , Murray Matthew F. , Ekwonu Adaora , Wildes Jennifer E. , Haedt‐Matt Alissa A. 
Published: July 2024

AbstractObjectiveEvidence suggests that interpersonal stress plays a role in maintaining binge eating and purging (e.g., self‐induced vomiting, misuse of laxatives). Stress is especially likely to promote engagement in maladaptive behaviour if the behaviour is habitual; therefore, individuals whose binge eating and/or purging are habitual may be particularly likely to engage in these behaviours in the context of interpersonal stress. We aimed to investigate this hypothesis in a sample of women with binge eating and/or purging using ecological momentary assessment (EMA).MethodWomen (N = 81) with binge‐eating and/or purging symptoms completed a self‐report measure assessing habit strength of binge eating and purging followed by a 14‐day EMA protocol assessing daily perceived interpersonal stress and binge‐eating and purging episodes.ResultsHabit strength of purging moderated the within‐person effect of interpersonal stress on purging frequency, such that higher daily stress was associated with greater same‐day purging frequency when purging was more habitual. Contrary to expectations, the interactive effect of habit strength of binge eating and daily interpersonal stress on same‐day binge‐eating frequency was non‐significant.ConclusionsFindings suggest that individuals with habitual purging may be vulnerable to engaging in purging when they are experiencing high levels of interpersonal stress.
Exploring neurocognitive features in adolescents and young adults with anorexia nervosa: Evidence from a longitudinal study
Authors: Wittek Tanja , Zeiler Michael , Truttmann Stefanie , Philipp Julia , Kopp Konstantin , Krauss Helene , Auer‐Welsbach Ellen , Ohmann Suanne , Sackl‐Pammer Petra , Werneck‐Rohrer Sonja , Laczkovics Clarissa , Mitterer Michaela , Schneider Andrea , Kahlenberg Leonie , Schmidt Ulrike , Karwautz Andreas , Wagner Gudrun 
Published: July 2024

AbstractObjectiveWe aimed to evaluate longitudinal changes in set‐shifting and central coherence in a predominantly adolescent cohort with anorexia nervosa (AN) and to explore whether these factors predict long‐term eating disorder outcomes.MethodNinety‐two female patients with AN (mean age: 16.2, range: 13–21 years) completed neurocognitive tests (Rey Complex Figure Test, Adapted Version of the Wisconsin Card Sorting Test) before and after 12 months of psychotherapeutic treatment (n = 45 Maudsley AN Treatment, MANTRa; n = 47 standard psychotherapy; groups not randomised). Eating disorder severity was assessed at baseline, after 6, 12 and 18 months.ResultsCentral coherence (indicated by an increase in the Rey Figure Style Index) and set‐shifting (indicated by a reduction in the percentage of perseverative errors) significantly improved over the course of treatment, with similar outcomes across groups. Lower central coherence was associated with higher eating disorder severity. Individuals with lower baseline set‐shifting ability tended to have worse eating disorder outcomes in the long‐term. However, this trend did not reach statistical significance in a multilevel linear mixed model.ConclusionsNeurocognitive difficulties in adolescents and young adults with AN can improve after treatment. Interventions specifically addressing flexibility in thinking and behaviour may contribute to treatment success.
Lifetime of the Gas Evolution Electrode of the Zn–H2 Storage System
Authors: Hahn Robert , Rosenfeld Oren , Markheim Chaim , Schamel Andreas 
Published: July 2024

ABSTRACTA novel electrically chargeable galvanic system is presented that efficiently stores energy in the form of zinc and releases hydrogen and electricity upon discharge. In this concept, oxygen is released at the gas electrode during charging, and zinc oxide is reduced to metallic zinc at the counter electrode. When the cell is discharged on demand, the zinc is converted back to zinc oxide, but the water is reduced at the gas electrode to produce hydrogen. The system can therefore be used not only to store electricity—in combination with a fuel cell—but also as an on‐demand hydrogen generator, for example, for industrial use. When used as an electrical storage system, the overall round‐trip efficiency can approach 50%, significantly exceeding the efficiency of alternative power‐to‐gas technologies. There are no hydrogen storage or transportation losses. The electrochemical cell combines two breakthrough technologies: a bifunctional catalyst for hydrogen and oxygen evolution reaction that survives thousands of oxidation and reduction cycles, and a dendrite‐free deposition of thick, high‐capacity zinc coatings that can be cycled almost indefinitely thanks to pulsed charge current and intelligent electronic control.
Parents' perception of treatment‐related toxicity in children treated according to the NOPHO ALL2008 protocol for acute lymphoblastic leukemia
Authors: Mogensen Nina , Kreicbergs Ulrika , Albertsen Birgitte K. , Lähteenmäki Päivi M. , Heyman Mats , Harila Arja 
Published: July 2024

AbstractThis study aimed to assess how parents perceived treatment‐related side effects during acute lymphoblastic leukemia (ALL) treatment. Parents of children 1–17.9 years at diagnosis in Sweden, Finland, and Denmark who were alive and in first remission ≥6 months after end of ALL treatment were asked to respond on specific items regarding how their child was affected by side effects related to vincristine (VCR), corticosteroids, peg‐asparaginase (ASP), and maintenance therapy, as well as overall impact of these treatments, complications in general, and their perception of impact on their child in comparison with other children with ALL. Parents of 307 children responded. More than a third reported that their child had been affected to a high extent by VCR (39.7%) and corticosteroids (35.8%), with walking difficulties, muscular weakness, pain, changes in appetite, and mood swings as the most common and severe symptoms. Reporting of these toxicities was lacking from the NOPHO ALL2008 database, except for peripheral paralysis (12.1%). For distinct toxicities reported in the NOPHO ALL2008 database, for example, thrombosis and pancreatitis, parent reports were similar to the database. Although a high overall negative impact during treatment was reported, parents generally rated the impact on their child as less, or similar, to other children with ALL. Parents perceived VCR and corticosteroid therapy, in particular, to have a negative impact on their child during ALL treatment, which was not captured in the NOPHO ALL2008 toxicity reporting. Our results highlight the importance of including patient/parent‐reported outcomes in toxicity reporting.
Natural and sustainable thermal storage solution for solar distillation system using sensible fiber material and latent PCM: Enhanced energy storage application
Authors: Thakur Vinay , Kumar Nitin 
Published: July 2024

AbstractThe current research work involves the design and performance assessment of a solar still, which is a conventional single‐slope basin‐type solar still (CSSBTSS) and a modified single‐slope basin‐type solar still (MSSBTSS) under the meteorological conditions of Solan city, Himachal Pradesh, India (30.90° N, 77.09° E). The individual and the combined effect of different sample quantities of sensible Himalayan Rambaan fibers (HRFs) and mass of latent paraffin wax (PW) A48 on the performance of MSSBTSS is evaluated and compared with CSSBTSS. The use of HRF material enhanced the evaporation rate significantly and improved the daytime distillates. Besides, different masses of latent PW filled inside the aluminum tubes improved the nocturnal distillates. For the analysis, three cases have been considered which are, namely: Case 1, solar still with sensible HRFs (MSSBTSS‐HRF); Case 2, solar still with latent PW A48 (MSSBTSS‐PW); and Case 3, solar still with sensible and latent material (MSSBTSS‐HRF‐PW). The results showed that the maximum thermal efficiency for Cases 1 and 2 was improved by 30.02% and 42.41% with five sample quantities of HRF material and 5000 g of PW. For Case 3, the maximum energy efficiency was 90.71% with a gain of 45.16% over CSSBTSS. The economic analysis concluded that the cost per liter of distillate yield produced using MSSBTSS‐HRF‐PW and CSSBTSS is ₹1.5 and ₹1.6, respectively. These outcomes showed the great potential of MSSBTSS‐HRF‐PW approach towards enhancing the overall performance and cost‐effectiveness of solar still.
The prenatal caregiving expectations questionnaire‐revised version: Factor structure, internal consistency, and initial construct validity
Authors: Røhder Katrine , Baumann Magnus Volden , Karstoft Karen‐Inge , Schleicher Ida , George Carol , Harder Susanne 
Published: July 2024

AbstractAn efficient, multidimensional instrument is needed to screen non‐optimal prenatal parental representations predictive of postnatal parenting behavior and child attachment. The present work aimed to revise and validate the Prenatal Caregiving Expectations Questionnaire—Revised (PCEQ‐R). Survey data from two independent samples of pregnant, primarily Danish, women (N = 300/322) were collected to 1) test the factor structure and select items for a 20‐item version, and 2) confirm the factor structure, examine internal consistency, and establish initial construct validity. Confirmatory factor analysis supported a three‐factor model of helpless‐dysregulated, anxious‐hyperactivated, and avoidant‐deactivated caregiving representations. Internal consistency was acceptable (α > .73). Construct validity analyses showed that higher helpless‐dysregulated caregiving was associated with low maternal antenatal attachment quality (rs = −.36) and intensity (rs = −.11), increased risk of perinatal depression (rs = .37), and trait anxiety (rs = .37). Higher anxious‐hyperactivated caregiving was associated with better maternal antenatal attachment quality (rs = .20) and higher intensity (rs = .26), while avoidant‐deactivated caregiving was not associated with maternal antenatal attachment. These findings support the validity and multidimensional structure of the measure. The homogenous nature of the sample limits generalizability of results. Future studies should examine predictive validity of the PCEQ‐R and include clinical samples.
Long journey of 16S rRNA‐amplicon sequencing toward cell‐based functional bacterial microbiota characterization
Authors: Jin Jianshi , Liu Xiongduo , Shiroguchi Katsuyuki 
Published: July 2024

AbstractBacteria often exist and function as a community, known as the bacterial microbiota, which consists of vast numbers of bacteria belonging to many bacterial species (taxa). Characterizing the bacterial microbiota needs high‐throughput approaches that enable the identification and quantification of many bacterial cells, and such approaches have been under development for more than 30 years. In this review, we describe the history of high‐throughput technologies based on 16S ribosomal RNA (rRNA) gene‐amplicon sequencing for the characterization of bacterial microbiotas. Then, we summarize the features and applications of current 16S rRNA gene‐amplicon sequencing approaches, including a recent achievement that enables the identification of individual cells with single‐base accuracy for 16S rRNA genes and the quantification of many identified cells. Furthermore, we present the prospects for further technical development, including the combined use of high‐throughput methods and other informative analyses, such as whole‐genome sequencing in the common unit of the cell, which enables bacterial microbiota characterization based on both the number of cells and their functions.
Using degradable oxidizing additives in the manufacturing of drip irrigation tapes to prevent environmental problems
Authors: Mohammadi Mohammadhadi , Khaledian Mohammadreza , Olfati Jamalali 
Published: July 2024

AbstractUsing tapes in drip irrigation is associated with environmental problems due to the accumulation of tapes in agricultural areas. Farmers either leave them on the fields or burn them or bury them. All three of these methods pose dangerous environmental hazards. To address this issue, it is recommended that these materials be produced from or with biodegradable materials. In this study, a biodegradable additive was used as a degradation accelerator in the production of tapes. After the production of these tapes, they were used under real conditions and during a growing season and in two treatments: below and on the soil surface, along with a canopy and without shade (beans and radishes). After 6 and 11 months, the tapes were sampled to investigate their degradation. The results showed that tapes made with oxo as an additive began to degrade more quickly than did conventional tapes. A reduction in properties such as weight (p < 0.05), turbidity (p < 0.05), and mechanical properties such as tensile strength at the rupture point (p < 0.05), elongation at the rupture point (p > 0.05), Young's modulus (p < 0.05) and toughness (p < 0.05) in tapes produced with oxo additives shows more and faster degradation than conventional tapes. Therefore, the use of oxo master batches in the production of tapes is possible and useful.
Available evidence on fetal liver changes detected by ultrasound in pregnant women with gestational diabetes mellitus: Systematic review
Authors: Da Correggio Karine Souza , Galluzzo Roberto Noya , von Wangenheim Aldo , Werner Heron , Castro Pedro Teixeira , Araujo Júnior Edward , Onofre Alexandre Sherlley Casimiro 
Published: July 2024

AbstractThe aim of this systematic review was to examine the available scientific literature on ultrasound‐detected fetal liver changes in pregnant women with gestational diabetes mellitus (GDM) and to explore the potential of these markers to inform clinical management and improve outcomes. A total of four articles investigating fetal liver changes in GDM pregnancies were selected. The studies varied in methodology, gestational age studied, and diagnostic criteria for GDM. Fetal liver indices, such as fetal liver length and fetal liver volume, emerged as potential markers for identifying GDM and predicting adverse outcomes. Studies suggest an association between fetal liver changes and GDM, with implications for both maternal glycemic control and fetal metabolic adaptation. Variability in study methodology highlights the need for standardized approaches to assess fetal hepatic indices and their correlation with GDM outcomes.