bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Dehydrogenative Alkenylation of Uracils via Palladium‐Catalyzed Regioselective C—H Activation.
Authors: Yu Yi‐Yun , Georg Gunda I. 
Published: July 2013

AbstractAn efficient procedure is elaborated for the synthesis of 5‐(E)‐alkenyl uracils by a regio‐ and stereoselective cross‐dehydrogenative coupling of uracils with alkenes.
ChemInform Abstract: First Synthesis and Biological Evaluation of Indeno[2,1‐e]pyrazolo[3,4‐b]pyrazin‐5‐one and Related Derivatives.
Authors: El‐Emary Talaat , El‐Kashef Hussein 
Published: July 2013

AbstractThe title indenopyrazolopyrazinone (II), synthesized by intramolecular Friedel—Crafts acylation of acid chloride (I), appears to be a versatile compound for the synthesis of a variety of indenopyrazolopyrazine derivatives.
ChemInform Abstract: Protonated DBU as Catalyst for Cascade Addition—Cyclization of 2‐Alkynylaniline and Carbon Disulfide.
Authors: Zhao Peng , Liao Qian , Gao Hongxin , Xi Chanjuan 
Published: July 2013

AbstractThe reaction provides a convenient route for the regio‐ and stereoselective synthesis of benzothiazine derivatives under mild conditions in the absence of any metal.
ChemInform Abstract: A Mild Efficient Iodine‐Catalyzed Synthesis of Novel Anticoagulants with 2,8‐Dioxabicyclo[3.3.1]nonane Core.
Authors: Ganguly Nemai C. , Mondal Pallab , Roy Sushmita 
Published: July 2013

AbstractOptimized conditions are developed for the coupling of 2‐hydroxychalcones and analogous α,β‐enones with 4‐hydroxycoumarin or dimedone to yield the title compounds as a novel class of potential anticoagulants
ChemInform Abstract: Improving Carbene—Copper Catalyzed Asymmetric Synthesis of α‐Aminoboronic Esters Using Benzimidazole‐Based Precursors.
Authors: Wen Kun , Wang Han , Chen Jinbo , Zhang He , Cui Xiaodan , Wei Chao , Fan Erkang , Sun Zhihua 
Published: July 2013

AbstractBy using the preformed carbene‐copper catalyst the reaction proceeds in shorter reaction times and in slightly better yields in comparison to the also realized one‐pot reactions with the carbene precursor and copper chloride.
ChemInform Abstract: Formal Regiocontrolled Hydroboration of Unbiased Internal Alkynes via Borylation/Allylic Alkylation of Terminal Alkynes.
Authors: Moure Abraham L. , Mauleon Pablo , Gomez Arrayas Ramon , Carretero Juan Carlos 
Published: July 2013

AbstractThis preparation of 1,2‐disubstituted vinylboranes is based on a directed borylation of terminal alkynes followed by Cu‐catalyzed allylic alkylation with Grignard reagents.
ChemInform Abstract: Synthesis of Six‐Membered Silacycles by Intramolecular Nucleophilic Substitution at Silicon Involving the Cleavage of Carbon—Silicon Bonds.
Authors: Onoe Masahiro , Morioka Toshifumi , Tobisu Mamoru , Chatani Naoto 
Published: July 2013

AbstractSix‐membered silacycles are available via the cleavage of an inert carbon‐silicon bond using organolithium reagents.
ChemInform Abstract: Concise Synthesis of the Tetracyclic Framework of Azadiradione: Tandem Radical Cyclization Route.
Authors: Yamashita Shuji , Naruko Akito , Yamada Takahiro , Hayashi Yujiro , Hirama Masahiro 
Published: July 2013

AbstractA concise radical route to the framework of azadiradione is developed, in which the four carbon—carbon bonds and seven stereocenters featuring the C13,14‐cis configuration are constructed in one step.
ChemInform Abstract: Synthesis of N‐Cbz‐Substituted β3‐Amino Ketones Utilizing 4‐Substituted 1,3‐Oxazinan‐6‐ones.
Authors: Sleebs Brad E. , Nguyen Nghi H. , Hughes Andrew B. 
Published: July 2013

AbstractThe approach to the synthetically important chiral β‐amino ketones involves diastereoselective acylation of 1,3‐oxazinan‐6‐ones followed by acidic decarboxylation.
ChemInform Abstract: Three New Orcinol‐Conjugated Hydrolysable Tannins from the Leaves of Cleyera japonica.
Authors: Oh Myeong Hwan , Park Kwan Hee , Kim Manh Heun , Kim Han Hyuk , Kim So Ra , Lee Min Won 
Published: July 2013

AbstractCleyeratannin A (I*a), B (I*b), C (II*) are isolated along with two known compounds from the leaves of Cleyera japonica (CJ).
ChemInform Abstract: A 14‐Membered Macrolide and Isocoumarin Derivatives from the Cultured Lichen Mycobionts of Graphis vestitoides.
Authors: Le Duy , Hoang Hoang , Takenaka Yukiko , Hamada Nobuo , Miyawaki Hiromi , Tanahashi Takao 
Published: July 2013

AbstractIsocoumarin (I) and the 14‐membered macrolide ((S)‐II) are isolated along with five known isocoumarin derivatives.
ChemInform Abstract: Lasiodiplodin Analogues from the Endophytic Fungus Sarocladium kiliense.
Authors: Zheng Wei Fa , et al. et al. 
Published: July 2013

AbstractThe 12‐membered ring lactone, (3S),(6R)‐6‐hydroxylasiodiplodin (I*) is isolated along with two known analogues from the normal Apriona germari (HOPE)‐associated fungus Sarocladium kiliense grown in rice medium.
ChemInform Abstract: Model Studies Towards the Challenging Angularly‐Oxygenated Core of Several Angucyclinones from an Oxidative Dearomatization Strategy.
Authors: Vila‐Gisbert Silvia , Urbano Antonio , Carreno M. Carmen 
Published: July 2013

AbstractOxone‐mediated oxidative dearomatization of tricyclic phenol (IV) yields p‐quinol (VI), which is converted into azicemycin‐type tricyclic model (VI) and aquayamycin‐type core model (X).
ChemInform Abstract: Discovery of 7‐Methoxy‐6‐ [4‐(4‐methyl‐1,3‐thiazol‐2‐yl)‐1H‐imidazol‐5‐yl]‐1,3‐benzothiazole (TASP0382088): A Potent and Selective Transforming Growth Factor‐β Type I Receptor Inhibitor as a Topical Drug for Alopecia.
Authors: Amada Hideaki , Asanuma Hajime , Koami Takeshi , Okada Atsushi , Endo Mayumi , Ueda Yasuji , Naruse Takumi , Ikeda Akiko 
Published: July 2013

AbstractThe title compound (I) is a selective and potent ALK5 inhibitor.
Evaluation of breakage kernels for liquid–liquid systems: Solution of the population balance equation by the least‐squares method
Authors: Solsvik Jannike , Borka Zsolt , Becker Per Julian , Sheibat‐Othman Nida , Jakobsen Hugo A. 
Published: July 2013

AbstractThe breakage frequency and daughter size distribution functions by Coulaloglou and Tavlarides[1] are frequently adopted closures in population balance (PB) modelling. A survey of the extensions and modifications of the Coulaloglou and Tavlarides[1] breakage frequency function is provided. Furthermore, the daughter size distribution functions within the statistical category, herein the model proposed by Coulaloglou and Tavlarides[1], are outlined. Most of the breakage models available in literature commonly assume binary breakage only. Thus, the daughter size distribution function suggested by Diemer and Olson[2] is of interest as higher order breakage can be modelled. The breakage closures are evaluated solving the population balance equation (PBE) for a liquid–liquid emulsification system in a stirred tank. The results obtained from a least‐squares solver are compared with the experimental data when available.
Interplay between Metal⋅⋅⋅π Interactions and Hydrogen Bonds: Some Unusual Synergetic Effects of Coinage Metals and Substituents
Authors: Gao Meng , Yang Xin , Cheng Jianbo , Li Qingzhong , Li Wenzuo , Loffredo Robert E. 
Published: July 2013

AbstractThe ternary systems of C2H4(C2H2or C6H6)‐MCN‐HF (M=Cu, Ag, Au) and the respective binary systems were investigated to study the interplay between metal⋅⋅⋅π interactions and hydrogen bonds. The metal⋅⋅⋅π interactions in C2H4‐MCN become stronger with the irregular order Ag<Cu<Au, while the hydrogen bonds in MCN‐HF become weaker following the same order. The metal⋅⋅⋅π interactions are weakened as the H atoms in the π system are replaced with electron‐withdrawing groups and enhanced by electron‐donating groups. Type 1 of these ternary systems, in which MCN acts as Lewis base and acid simultaneously, is more stable than type 2, in which C2H4acts as a double Lewis base. Negative cooperativity is present in type 2 ternary systems with a weakening of the metal⋅⋅⋅π interactions and the hydrogen bonds. Positive cooperativity is found in type 1 ternary systems with an enhancement of the metal⋅⋅⋅π interactions and the hydrogen bonds, except for C2(CN)4‐AuCN‐HF‐1. The weaker metal⋅⋅⋅π interaction in C6H6‐AuCN has a greater enhancing effect on the hydrogen bond in AuCN‐HF than those in C2H4‐AuCN and C2H2‐AuCN. These synergetic effects were analyzed with the natural bond orbital and energy decomposition.
Preparation of Porous ZrO2‐Based Composite Oxides Containing W, Cr, Mo, or V Through a Wall Ion‐Exchange Method
Authors: Suh Insuhk , Hori Shun‐suke , Tanaka Masashi , Iwamoto Masakazu 
Published: July 2013

AbstractMOx–ZrO2 (M = W, Cr, Mo, or V) composite oxides with high surface areas and hexagonal pore structures were prepared through a wall ion‐exchange (WIE)–calcination method. A composite (ZS) of Zr(SO4)2·4H2O and cetyltrimethylammonium bromide with ordered hexagonal structure was cast into solutions of M oxyanions. The efficiency of the WIE treatment was first studied on the solutions of tungsten oxyanion in detail. The surface areas of tungsten‐oxyanion‐introduced ZSs (W‐ZSs) after calcination at 673 K in air for 2 h were 3–248 m2 g–1 depending on the pH values of the exchange solutions. The treatments at pH = 5.6–10.1 resulted in the formation of porous materials with surface areas of 38–248 m2 g–1 and pore sizes of approximately 1.2 nm, whereas treatments at pH = 2.5–4.8 gave surface areas of 3–18 m2 g–1. The predominant oxyanion in the former region was a monomeric ion, WO42–. The WIE–calcination method was thus applied to the preparation of Cr‐, Mo‐, or V‐containing ZrO2 composite oxides in which the respective monomeric oxyanions were employed as the exchange ions by adjusting the pH values of the solutions. The surface areas of calcined Cr‐, Mo‐, and V‐ZS were 348, 251, and 229 m2 g–1, respectively, and pore sizes were 1.00–1.12 nm. The WIE–calcination method was proved to be a general method for the preparation of porous ZrO2‐based oxides.
NSR Compliance—Are You Ready?
Authors: McGuffey Carroll “Mack” 
Published: July 2013

AbstractIt should come as no surprise in today's highly regulated world that a permit governing air quality is required before constructing a new natural gas—fired electric‐generating unit. And perhaps it would not surprise many to learn that the same type of permit is needed prior to making significant changes to an existing gas unit. However, to the uninitiated, the full reach of the program known as “New Source Review” (NSR) can come as quite a shock. Although coal‐fired utilities have been the primary target of NSR enforcement for over a decade, natural gas—fired plants could be next.
Geomorphic signatures of glacial activity in the Alba Patera volcanic province: Implications for recent frost accumulation on Mars
Authors: Sinha Rishitosh K. , Murty Sripada V. S. 
Published: July 2013

AbstractGlacial/periglacial landforms lying within impact craters on Mars have led to the identification of two mechanisms for their formation: (1) intermittent deposition of atmospherically emplaced snow/ice during past spin‐axis/orbital conditions and (2) flow of debris‐covered ice‐rich deposits. The maximum presence of the young ice/snow‐rich features (thermal contraction crack polygons, gullies, arcuate ridges, and lobate debris tongues) was observed on the pole‐facing slope, indicating that this slope was the preferred site for ice/snow accumulation (during the last 10 Ma). In this study, we investigated 30 craters lying in the Alba Patera volcanic province in the latitudinal bands between 45°N and 32.4°N. Morphological comparison of the younger ice/snow‐rich features in these craters led us to conclude that glacial/periglacial features in Alba Patera are mainly present within pole‐facing slopes of craters lying within 45°N–39°N. The craters lying within 40.2°N–40°N did not show any glacial/periglacial features. We suggest that the formation of these young ice/snow‐rich features follows the same orientation trends as those of other older (>10 Ma) glacial features (debris‐covered ice/snow‐rich large deposits at the base of the crater wall) in the region. The present work has revealed that the onset of physical processes that result in the formation of glacial/periglacial landforms is also dependent on the changes in elevation ranges of the investigated craters in Alba Patera. Our results confirm past inferences for accumulation of ice/snow on Mars and suggest that the period of ice/snow accumulation activity in Alba Patera occurred throughout the Amazonian and lasted until the recent past, i.e., 2.1–0.4 Ma.
Improved simulation of Indian summer monsoon in latest NCEP climate forecast system free run
Authors: Saha Subodh K. , Pokhrel Samir , Chaudhari Hemantkumar S. , Dhakate Ashish , Shewale Swati , Sabeerali C. T. , Salunke Kiran , Hazra Anupam , Mahapatra Somnath , Rao A. Suryachandra 
Published: July 2013

ABSTRACTSimulation of Indian summer monsoon features by latest coupled model of National Centers for Environmental Prediction (NCEPs) Climate Forecast System version 2 (CFSv2) is attempted in its long run. Improvements in the simulation of Indian summer monsoon as compared with previous version (CFSv1) is accessed and areas which still require considerable refinements are introduced. It is found that, spatial pattern of seasonal mean rainfall and wind circulations are more realistic in CFSv2 as compared with CFSv1. Variance and northward propagation of intraseasonal oscillation (ISO), which also contribute to the seasonal mean rainfall are remarkably improved. However, the central Indian dry bias still persists and amplified. Pervasive cold bias in surface (2 m air temperature) as well as in the whole troposphere is further increased in CFSv2. These cold biases may be partly attributed to the lack of model's ability to realistically simulate the ratio of convective and stratiform rainfall. Sea‐surface temperature (SST) over the Indian Ocean is underestimated in CFSv2. However, CFSv1 shows east–west dipole structure in the bias. The teleconnection of El Nino Southern Oscillation (ENSO) and Indian summer monsoon rainfall (ISMR) in terms of Niño3 SST and monsoon rainfall correlation is more realistic in the latest version of the model. Overall, there are substantial improvements in CFSv2 as compared with CFSv1, but it has to evolve further to realistically simulate the mean and variability of ISMR.
Fate of Escherichia coliO157:H7 and Salmonella in soil and lettuce roots as affected by potential home gardening practices
Authors: Erickson Marilyn C , Liao Jean , Payton Alison S , Webb Cathy C , Ma Li , Zhang Guodong , Flitcroft Ian , Doyle Michael P , Beuchat Larry R 
Published: July 2013

AbstractBACKGROUNDThe survival and distribution of enteric pathogens in soil and lettuce systems were investigated in response to several practices (soil amendment supplementation and reduced watering) that could be applied by home gardeners.RESULTSLeaf lettuce was grown in manure compost/top soil (0:5, 1:5 or 2:5 w/w) mixtures. Escherichia coli O157:H7 or Salmonella was applied at a low or high dose (103 or 106 colony‐forming units (CFU) mL−1) to the soil of seedlings and mid‐age plants. Supplementation of top soil with compost did not affect pathogen survival in the soil or on root surfaces, suggesting that nutrients were not a limiting factor. Salmonella populations on root surfaces were 0.7–0.8 log CFU g−1 lower for mid‐age plants compared with seedlings. E. coli O157:H7 populations on root surfaces were 0.8 log CFU g−1 lower for mid‐age plants receiving 40 mL of water compared with plants receiving 75 mL of water on alternate days. Preharvest internalization of E. coli O157:H7 and Salmonella into lettuce roots was not observed at any time.CONCLUSIONBased on the environmental conditions and high pathogen populations in soil used in this study, internalization of Salmonella or E. coli O157:H7 into lettuce roots did not occur under practices that could be encountered by inexperienced home gardeners. © 2013 Society of Chemical Industry
Complex Trauma Exposure and Symptoms in Urban Traumatized Children: A Preliminary Test of Proposed Criteria for Developmental Trauma Disorder
Authors: Stolbach Bradley C. , Minshew Reese , Rompala Vikki , Dominguez Renee Z. , Gazibara Tanja , Finke Robert 
Published: July 2013

Recently, a new diagnostic construct, developmental trauma disorder (DTD), was proposed to describe the effects of chronic exposure to violence in combination with disruptions in caregiving systems. This study uses archival data to field test the consensus proposed diagnostic criteria for DTD in a sample of urban children (N = 214). Children with complex trauma histories as defined in the proposed DTD Criterion A were much more likely to meet the proposed DTD symptom criteria than children who did not meet the exposure criterion. This field trial of the proposed DTD criteria suggests that the proposed construct of DTD is useful for describing the symptoms induced by ongoing traumatic stressors and disrupted caregiving and that the proposed symptom criteria can differentiate children with histories of exposure to developmental trauma from other trauma‐exposed children.
Structure of Metallo‐Supramolecular Micellar Gels
Authors: Mugemana Clément , Joset Arnaud , Guillet Pierre , Appavou Marie‐Sousai , De Souza Nicolas , Fustin Charles‐André , Leyh Bernard , Gohy Jean‐François 
Published: July 2013

AbstractA small‐angle neutron scattering investigation of metallo‐supramolecular micellar gels built from polystyrene‐block‐poly(tert‐butylacrylate) PS‐b‐PtBA‐tpy (‐tpy: terpyridine) block copolymers and transition metal ions is presented. The influence of the copolymer concentration on the structure and spatial organization of the micelles, as well as the impact of the subsequent addition of metal ions (Fe(II), Ni(II), and Zn(II)) on these characteristics is extensively studied. The experimental scattering cross‐sections are fitted with an analytical formula based on the Percus–Yevick hard‐sphere model and on the Pedersen–Gerstenberg model for the structure and the form factor, respectively. The resulting structural information is correlated with previously performed light scattering and rheology experiments.magnified image
Facile Synthesis of Hydroxy‐Functionalized Cycloolefin Copolymer Using ω‐Alkenylaluminium as a Comonomer
Authors: Shiono Takeshi , Sugimoto Mitsunori , Hasan Tariqul , Cai Zhengguol 
Published: July 2013

Copolymerization of norbornene and 7‐octenyldiisobutylaluminium is conducted by the catalytic system of ansa‐dimethylsilylene(fluorenyl)(amido)dimethyltitanium, Me2Si(NtBu)(fluorenyl)TiMe2 (1), activated with Ph3CB(C6F5)4 to produce copolymers with pendant alkylaluminium groups. The termination of the copolymers with methanol gives poly(norbornene‐co‐oct‐1‐ene). Termination with oxygen gas gives poly(norbornene‐co‐oct‐1‐ene‐co‐oct‐7‐en‐1‐ol) because the oxidation of the pendant alkylaluminium groups with oxygen is not quantitative. Terpolymerization of norbornene, oct‐1‐ene, and 7‐octenyldiisobutylaluminium are also conducted, where the content of the hydroxy groups and the glass transition temperature are independently controlled by the molar ratio of each comonomer in feed.
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A method to validate the accuracy of a centralised district diabetes register
Authors: Gillani SMR , Nayak AU , Thiruvenkatasamy K , Baskar V , Singh BM , Viswanath A 
Published: July 2013

AbstractAn accurate and valid district diabetes register is needed to identify people with diabetes. Quality assurance of such a register is vital to deliver high‐standard patient care. We report the findings of a methodical process of validation of the Wolverhampton District Diabetes Register (WDDR) post extraction of information from general practitioner (GP) databases, and propose an algorithm for resolving any disparity between the two data registers.Historic diabetes register data were matched with GP databases; discrepancies were checked with GP practices and updated on the WDDR. Unidentifiable people were subject to demographic checks with the Demographic Batch Service (DBS). DBS information was used to identify patients by contacting them directly or by contacting their GP practices. Diagnostic discrepancies were corrected by biochemical checks or identifying coding errors in the GP database.Of 2565 people unmatched with GP databases, 2380 had an identifiable GP. After checking with GP practices, 1244 (48.5%) were identified to have coding errors, 61 (2.4%) deceased and 333 (13%) with diagnostic inaccuracy of diabetes. A total of 927 (36%) patients with no identifiable GP were subject to demographic checks. Of these, 237 (9.2%) were found to be in the area and registered with another GP, 220 (8.6%) had no identifiable GP, 422 (16.4%) patients were not in the area, and 48 (1.9%) were deceased.To maintain a valid district diabetes register (WDDR), a rolling mechanism of demographic cross checks is required at regular intervals to reduce the number of discrepancies and increase the accuracy of such a register. Copyright © 2013 John Wiley & Sons.
Peer support: time to tap the (largely) untapped
Authors: Simmons David 
Published: July 2013

AbstractThere is growing evidence that the physical and mental health of people with, or at risk of, diabetes can benefit from support from a person with diabetes: known as diabetes peer support. Peer support involves the social and emotional help that supplements the assistance provided by health professionals and others in the life of the person with diabetes. By sharing, discussing, finding and facilitating the ways that can improve diabetes and overcome barriers to care and self‐care, metabolic control and wellbeing can improve. Linking peer support to clinical care is thought to strengthen its effectiveness. Peer support complements diabetes education and facilitates implementation of the knowledge gained.There are a range of different ways in which peer support can be provided. Peer support might arise from a casual discussion with another person with diabetes or within a more structured programme. The degree of training can vary from life with diabetes in the casual encounter, to group leadership, to paraprofessional training including motivational interviewing and a range of educational and management skills. The media for delivery vary from face‐to‐face, telephone and online approaches.At a time of a growing diabetes epidemic, peer support could well be a key strategy in supporting those with and at risk of diabetes, reducing downstream demands on health services while improving quality of life. If this turns out to be the case, every neighbourhood, village and clinic should have one or more peer coaches to support diabetes prevention and diabetes management. Copyright © 2013 John Wiley & Sons.This paper was presented as the 2013 Janet Kinson Lecture at the 2013 Diabetes UK Annual Professional Conference held in Manchester