bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association between operative position and postoperative nausea and vomiting in patients undergoing laparoscopic sleeve gastrectomy
Authors: Li Zhao-Peng , Song Yan-Cheng , Li Ya-Li , Guo Dong , Chen Dong , Li Yu 
Published: July 2024

BACKGROUND
Bariatric surgery is one of the most effective ways to treat morbid obesity, and postoperative nausea and vomiting (PONV) is one of the common complications after bariatric surgery. At present, the mechanism of the high incidence of PONV after weight-loss surgery has not been clearly explained, and this study aims to investigate the effect of surgical position on PONV in patients undergoing bariatric surgery.
AIM
To explore the effect of the operative position during bariatric surgery on PONV.
METHODS
Data from obese patients, who underwent laparoscopic sleeve gastrectomy (LSG) in the authors’ hospital between June 2020 and February 2022 were divided into 2 groups and retrospectively analyzed. Multivariable logistic regression analysis and the t -test were used to study the influence of operative position on PONV.
RESULTS
There were 15 cases of PONV in the supine split-leg group (incidence rate, 50%) and 11 in the supine group (incidence rate, 36.7%) (P = 0.297). The mean operative duration in the supine split-leg group was 168.23 ± 46.24 minutes and 140.60 ± 32.256 minutes in the supine group (P < 0.05). Multivariate analysis revealed that operative position was not an independent risk factor for PONV (odds ratio = 1.192, 95% confidence interval: 0.376-3.778, P = 0.766).
CONCLUSION
Operative position during LSG may affect PONV; however, the difference in the incidence of PONV was not statistically significant. Operative position should be carefully considered for obese patients before surgery.
Preoperative albumin-bilirubin score predicts short-term outcomes and long-term prognosis in colorectal cancer patients undergoing radical surgery
Authors: Diao Yu-Hang , Shu Xin-Peng , Tan Can , Wang Li-Juan , Cheng Yong 
Published: July 2024

BACKGROUND
The albumin-bilirubin (ALBI) score is a serum biochemical indicator of liver function and has been proven to have prognostic value in a variety of cancers. In colorectal cancer (CRC), a high ALBI score tends to be associated with poorer survival.
AIM
To investigate the correlation between the preoperative ALBI score and outcomes in CRC patients who underwent radical surgery.
METHODS
Patients who underwent radical CRC surgery between January 2011 and January 2020 at a single clinical center were included. The ALBI score was calculated by the formula (log10 bilirubin × 0.66) + (albumin × -0.085), and the cutoff value for grouping patients was -2.8. The short-term outcomes, overall survival (OS), and disease-free survival (DFS) were calculated.
RESULTS
A total of 4025 CRC patients who underwent radical surgery were enrolled in this study, and there were 1908 patients in the low ALBI group and 2117 patients in the high ALBI group. Cox regression analysis revealed that age, tumor size, tumor stage, ALBI score, and overall complications were independent risk factors for OS; age, tumor stage, ALBI score, and overall complications were identified as independent risk factors for DFS.
CONCLUSION
A high preoperative ALBI score is correlated with adverse short-term outcomes, and the ALBI score is an independent risk factor for OS and DFS in patients with CRC undergoing radical surgery.
Effect of rapid rehabilitation nursing on improving clinical outcomes in postoperative patients with colorectal cancer
Authors: Song Jing-Yan , Cao Jing , Mao Jian , Wang Jiang-Lian 
Published: July 2024

BACKGROUND
Surgical resection is the cornerstone treatment for colorectal cancer. Rapid rehabilitation care predicated on evidence-based medical theory aims to improve postoperative nursing care, subsequently reducing the physical and mental traumatic stress response and helping patients who undergo surgery recover rapidly.
AIM
To assess the effect of rapid rehabilitation care on clinical outcomes, including overall postoperative complications, anastomotic leaks, wound infections, and intestinal obstruction in patients with colorectal cancer.
METHODS
We searched the PubMed, Web of Science, Embase, Elsevier Science Direct, and Springer Link databases from January 1, 2010, to January 1, 2024, to screen eligible studies on rapid rehabilitation care among patients who underwent colorectal cancer surgery. Patients were screened based on the inclusion and exclusion criteria. RevMan 5.4 software was used for statistical analysis of the data.
RESULTS
Twelve studies were enrolled, which included 2420 patients. The results showed that rapid rehabilitation care decreased the incidence of overall postoperative complications (OR: 0.44, 95%CI: 0.26–0.74, P = 0.002), anastomotic leaks (OR: 0.68, 95%CI: 0.41–1.12, P = 0.13), wound infections (OR: 0.45, 95%CI: 0.29–0.72, P = 0.0007), and intestinal obstruction (OR: 0.54, 95%CI: 0.34–0.86, P = 0.01) compared to conventional care. Further trials and studies are needed to confirm these results.
CONCLUSION
Rapid rehabilitation care decreased the occurrence of postoperative complications, anastomotic leaks, wound infections, and intestinal obstruction compared to conventional care in patients who underwent colorectal surgery. Therefore, promoting the application of rapid rehabilitation care in clinical practice cannot be overemphasized.
Impact of nutritional support on immunity, nutrition, inflammation, and outcomes in elderly gastric cancer patients after surgery
Authors: Chen Xiao-Wan , Guo Xiao-Chun , Cheng Fen 
Published: July 2024

BACKGROUND
Postoperative rehabilitation of elderly patients with gastric cancer has always been the focus of clinical attention. Whether the intervention by a full-course nutritional support team can have a positive impact on the postoperative immune function, nutritional status, inflammatory response, and clinical outcomes of this special population has not yet been fully verified.
AIM
To evaluate the impact of full-course nutritional support on postoperative comprehensive symptoms in elderly patients with gastric cancer.
METHODS
This is a retrospective study, including 60 elderly gastric cancer patients aged 70 years and above, divided into a nutritional support group and a control group. The nutritional support group received full postoperative nutritional support, including individualized meal formulation, and intravenous and parenteral nutrition supplementation, and was regularly evaluated and adjusted by a professional nutrition team. The control group received routine postoperative care.
RESULTS
After intervention, the proportion of CD4+ lymphocytes (25.3% ± 3.1% vs 21.8% ± 2.9%, P < 0.05) and the level of immunoglobulin G (12.5 G/L ± 2.3 G/L vs 10.2 G/L ± 1.8 G/L, P < 0.01) were significantly higher in the nutritional support group than in the control group; the changes in body weight (-0.5 kg ± 0.8 kg vs -1.8 kg ± 0.9 kg, P < 0.05) and body mass index (-0.2 ± 0.3 vs -0.7 ± 0.4, P < 0.05) were less significant in the nutritional support group than in the control group; and the level of C-reactive protein (1.2 mg/L ± 0.4 mg/L vs 2.5 mg/L ± 0.6 mg/L, P < 0.01) and WBC count (7.2 × 109/L ± 1.5 × 109/L vs 9.8 × 109/L ± 2.0 × 109/L, P < 0.01) were significantly lower in the nutritional support group than in the control group. In addition, patients in the nutritional support group had a shorter hospital stay (10.3 d ± 2.1 d vs 14.8 d ± 3.6 d, P < 0.05) and lower incidence of infection (15% vs 35%, P < 0.05) in those of the control group.
CONCLUSION
The intervention by the nutritional support team has a positive impact on postoperative immune function, nutritional status, inflammatory response, and clinical outcomes in elderly patients with gastric cancer.
Potential applications of single-incision laparoscopic totally preperitoneal hernioplasty
Authors: Wang Xiao-Jun , Fei Ting , Xiang Xiong-Hua , Wang Quan , Zhou En-Cheng 
Published: July 2024

BACKGROUND
The totally preperitoneal (TPP) approach is a new concept that was recently introduced. Although the TPP approach combined with single-incision laparoscopic hernia repair has its own advantages, there is little evidence reflecting the characteristics and feasibility of either approach.
AIM
To analyze the potential applications of single-incision laparoscopic TPP (SIL-TPP) inguinal hernia hernioplasty for the treatment of inguinal hernias.
METHODS
A total of 152 SIL-TPP surgeries were performed at the First Affiliated Hospital of Ningbo University from February 2019 to November 2022. A single-port, named Iconport, and standard laparoscopic instruments were used during the operation. Demographic data, intraoperative parameters and short-term postoperative outcomes were collected and retrospectively analyzed.
RESULTS
The demographic data of 152 patients underwent SIL-TPP were shown in Table 1 . The average age was 49.5 years (range from 21 to 81 years). The average body mass index was 27.7 kg/m2 (range from 17.7 kg/m2 to 35.6 kg/m2). SIL-TPP were conducted successfully in 147 patients. Three patients were converted to the SIL-transabdominal preperitoneal laparoscopic herniorrhaphy at the initial stage of the study due to a lack of experience. In 2 patients with incisional hernias, an auxiliary operation hole was added during the SIL-TPP procedure, as required for surgery. The mean operative time was 64.5 minutes (range: 36.0-110.0 minutes) for unilateral direct and femoral hernias and 81.6 minutes for indirect hernias (range: 40.0-150.0 minutes). The mean postoperative hospital stay was 3.4 days.
CONCLUSION
SIL-TPP is feasible and has advantages for inguinal hernia repair. SIL-TPP has potential benefits for patients with various abdominal wall hernias. Consequently, doctors should be encouraged to actively apply the TPP approach combined with a single incision in their daily work.
Clinical significance of preoperative nutritional status in elderly gastric cancer patients undergoing radical gastrectomy: A single-center retrospective study
Authors: Zhao Xi-Ning , Lu Jing , He Hong-Yong , Ge Sheng-Jin 
Published: July 2024

BACKGROUND
The population of elderly patients with gastric cancer is increasing, which is a major public health issue in China. Malnutrition is one of the greatest risk factors for adverse clinical outcomes in elderly patients with gastric cancer.
AIM
To investigate the preoperative nutritional status and its association with delayed discharge of elderly gastric cancer patients following radical gastrectomy.
METHODS
A total of 783 patients aged 65 years and older harboring gastric adenocarcinoma and following radical gastrectomy were retrospectively analyzed from the prospectively collected database of Zhongshan Hospital of Fudan University between January 2018 and May 2020.
RESULTS
The overall rate of malnutrition was 31.8%. The incidence of postoperative complications was significantly higher in the malnourished group compared to the well-nourished group (P < 0.001). Nutritional characteristics in the malnourished group, including body mass index, prognostic nutritional index (PNI), albumin, prealbumin, and hemoglobin, were all significantly lower than those in the well-nourished group. The percentage of patients who received postoperative total nutrient admixture was lower in the malnourished group compared to the well-nourished group (22.1% vs 33.5%, P = 0.001). Age ≥ 70 years (HR = 1.216, 95%CI: 1.048-1.411), PNI < 44.5 (HR = 1.792, 95%CI: 1.058-3.032), operation time ≥ 160 minutes (HR = 1.431, 95%CI: 1.237-1.656), and postoperative complications grade III or higher (HR = 2.191, 95%CI: 1.604-2.991) were all recognized as independent risk factors associated with delayed discharge.
CONCLUSION
Malnutrition is relatively common in elderly patients undergoing gastrectomy. Low PNI is an independent risk factor associated with delay discharge. More strategies are needed to improve the clinical outcome of these patients.
Postoperative body weight change and its influencing factors in patients with gastric cancer
Authors: Li Yan , Huang Li-Hua , Zhu Hui-Di , He Ping , Li Bei-Bei , Wen Li-Jing 
Published: July 2024

BACKGROUND
The high incidence and mortality of gastric cancer (GC) pose a significant threat to human life and health, and it has become an important public health challenge in China. Body weight loss is a common complication after surgical treatment in patients with GC and is associated with poor prognosis and GC recurrence. However, current attention to postoperative weight change in GC patients remains insufficient, and the descriptions of postoperative weight change and its influencing factors are also different.
AIM
To investigate body weight changes in patients with GC within 6 mo after gastrectomy and identify factors that influence dynamic body weight changes.
METHODS
We conducted a prospective longitudinal study of 121 patients with GC and collected data before (T0) and 1 (T1), 3 (T2), and 6 (T3) mo after gastrectomy using a general data questionnaire, psychological distress thermometer, and body weight measurements. The general estimation equation (GEE) was used to analyze the dynamic trends of body weight changes and factors that influence body weight changes in patients with GC within 6 mo of gastrectomy.
RESULTS
The median weight loss at T1, T2, and T3 was 7.29% (2.84%, 9.40%), 11.11% (7.64%, 14.91%), and 14.75% (8.80%, 19.84%), respectively. The GEE results showed that preoperative body mass index (BMI), significant psychological distress, religious beliefs, and sex were risk factors for weight loss in patients with GC within 6 mo after gastrectomy (P < 0.05). Compared with preoperative low-weight patients, preoperative obese patients were more likely to have weight loss (β = 14.685, P < 0.001). Furthermore, patients with significant psychological distress were more likely to lose weight than those without (β = 2.490, P < 0.001), and religious patients were less likely to lose weight 6 mo after gastrectomy than those without religious beliefs (β = -6.844, P = 0.001). Compared to female patients, male patients were more likely to experience weight loss 6 mo after gastrectomy (β = 4.262, P = 0.038).
CONCLUSION
Male patients with GC with high preoperative BMI, significant psychological distress, and no religious beliefs are more likely to lose weight after gastrectomy.
Cost burden following esophagectomy: A single centre observational study
Authors: Buchholz Vered , Lee Dong Kyu , Liu David S , Aly Ahmad , Barnett Stephen A , Hazard Riley , Le Peter , Kioussis Benjamin , Muralidharan Vijayaragavan , Weinberg Laurence 
Published: July 2024

BACKGROUND
Cost analyses of patients undergoing esophagectomy is valuable for identifying modifiable expenditure drivers to target and curtail costs while improving the quality of care. We aimed to define the cost-complication relationship after esophagectomy and delineate the incremental contributions to costs.
AIM
To assess the relationship between the hospital costs and potential cost drivers post esophagectomy and investigate the relationship between the cost-driving variables (predicting variables) and hospital costs (dependent variable).
METHODS
In this retrospective single center study, the severity of complications was graded using the Clavien-Dindo (CD) classification system. Key esophagectomy complications were categorized and defined according to consensus guidelines. Raw costing data included the in-hospital costs of the index admission and any unplanned admission within 30 postoperative days. We used correlation analysis to assess the relationship between key clinical variables and hospital costs (in United States dollars) to identify cost drivers. A mediation model was used to investigate the relationship between these variables and hospital costs.
RESULTS
A total of 110 patients underwent primary esophageal resection. The median admission cost was $47822.7 (interquartile range: 35670.2-68214.0). The total effects on costs were $13593.9 (95%CI: 10187.1-17000.8, P < 0.001) for each increase in CD severity grade, $4781 (95%CI: 3772.7-5789.3, P < 0.001) for each increase in the number of complications, and $42552.2 (95%CI: 8309-76795.4, P = 0.015) if a key esophagectomy complication developed. Key esophagectomy complications drove the costs directly by $11415.7 (95%CI: 992.5-21838.9, P = 0.032).
CONCLUSION
The severity and number of complications, and the development of key esophagectomy complications significantly contributed to total hospital costs. Continuous institutional initiatives and strategies are needed to enhance patient outcomes and minimize costs.
Impacts of different pancreatic resection ranges on endocrine function in Suncus murinus
Authors: Li Ru-Jia , Yang Ting , Zeng Yu-Hao , Natsuyama Yutaro , Ren Ke , Li Jun , Nagakawa Yuichi , Yi Shuang-Qin 
Published: July 2024

BACKGROUND
Surgical intervention involving the pancreas can lead to impaired glucose tolerance and other types of endocrine dysfunction. The scope of pancreatectomy and whether it includes the ventral pancreas are the key factors in the development of postoperative diabetes. The ventral and dorsal pancreases are almost separated in Suncus murinus (S. murinus ).
AIM
To investigate the effects of different extents of pancreatic resection on endocrine function in S. murinus .
METHODS
Eight-week-old male S. murinus shrews were randomly divided into three experimental groups according to different pancreatic resection ranges as follows: ventral pancreatectomy (VPx) group; partial pancreatectomy (PPx) group; subtotal pancreatectomy (SPx) group; and a sham-operated group. Postprandial serum insulin, glucagon-like peptide-1 (GLP-1), pancreatic polypeptide (PP), and somatostatin (SST) levels, as well as food intake, weight, blood glucose, and glucose tolerance were regularly measured for each animal.
RESULTS
S. murinus treated with PPx and SPx suffered from varying degrees of impaired glucose tolerance, but only a small proportion of the SPx group developed diabetes. Only S. murinus in the SPx group showed a significant decrease in food intake accompanied by severe weight loss, as well as a significant increase in postprandial serum GLP-1 levels. Postprandial serum PP levels decreased in both the VPx and PPx groups, but not in the SPx group. Postprandial serum SST levels decreased in both VPx and PPx groups, but the decrease was marginal.
CONCLUSION
Severe weight loss after pancreatectomy may be related to loss of appetite caused by compensatory elevation of GLP-1. PP and GLP-1 may play a role in resisting blood glucose imbalance.
Multidisciplinary management of ulcerative colitis complicated by immune checkpoint inhibitor-associated colitis with life-threatening gastrointestinal hemorrhage: A case report
Authors: Hong Na , Wang Bo , Zhou Hang-Cheng , Wu Zheng-Xiang , Fang Hua-Ying , Song Geng-Qing , Yu Yue 
Published: July 2024

BACKGROUND
Programmed cell death 1 (PD-1) inhibitors are immune checkpoint inhibitors (ICI) that have demonstrated significant efficacy in treating various advanced malignant tumors. While most patients tolerate treatment well, several adverse drug reactions, such as fatigue, myelosuppression, and ICI-associated colitis, have been reported.
CASE SUMMARY
This case involved a 57-year-old male patient with ulcerative colitis complicated by hepatocarcinoma who underwent treatment with tirelizumab (a PD-1 inhibitor) for six months. The treatment led to repeated life-threatening lower gastrointestinal hemorrhage. The patient received infliximab, vedolizumab, and other salvage procedures but ultimately required subtotal colectomy due to uncontrollable massive lower gastrointestinal bleeding. Currently, postoperative gastrointestinal bleeding has stopped, the patient’s stool has turned yellow, and his full blood cell count has returned to normal.
CONCLUSION
This case highlights the necessity of early identification, timely and adequate treatment of ICI-related colitis, and rapid escalation to achieve the goal of improving prognosis.
Upaya Preventif: Edukasi dari Pemerintahan untuk Mencegah Gelandangan dan Pengemis
Authors: Ainnisa Intan Nur , Aulia Syifa Siti 
Published: July 2024

The government has an important role in carrying out preventive efforts to prevent homelessness and beggars, one of which is in the Yogyakarta area through the Social Service. This study uses a phenomenological method with a qualitative approach to explore phenomena related to the preventive efforts of DIY social services to prevent homelessness and beggars through counseling and education. The aim of this article is to provide an overview of the activities of the DIY Social Service in implementing education to prevent homelessness and beggars by examining three things, namely planning, implementation and obstacles in implementing counseling and education as a form of preventive effort. In planning, the social service makes a plan by first identifying its objectives, analyzing its targets, preparing materials, planning scheduling, preparing presenters to deliver outreach and public education. Counseling and education to the community is carried out by the DIY social service through various media such as print media, electronic media, and through cultural media. DIY social services face several obstacles, budget constraints and lack of human resources. However, the DIY social service has a solution to face these obstacles by inviting and collaborating with other institutions and community leaders to help spread outreach and education to the community.
HUBUNGAN ASUPAN ZAT BESI DENGAN LINGKAR LENGAN ATAS PADA REMAJA PUTRI
Authors: Fauziah Lilia Faridatul , Royyifi Arifin Ahmad David , Duwairoh Alifea Meta , Antika Falentina Indi 
Published: July 2024

Introduction : Chroniic eineirgy deifiiciieincy (CEiD) iis a condiitiion wiith a long and chroniic lack of eineirgy and proteiiin. CEiD can bei deiteirmiineid by meiasuriing MUAC (Miid Uppeir Arm Ciircumfeireincei) as onei of iindiicator for meiasuriing nutriitiional status, wiith a threishold of 23.5 cm. Thiis study deiteirmiineid thei associiatiion beitweiein iiron iintakei and nutriitiional status baseid on meiasureimeint of MUAC on feimalei teieinangeir, Tuban Diistriict. Method: Thiis was a cross-seictiional approach.Thei sample were seileicteid by clusteir random sampliing teichniiquei and obtaiineid 237 reispondeints. Iindeipeindeint and deipeindeint variiablei data weirei colleicteid through MUAC measurement and iinteirviieiw teichniiqueis by Recall 24 hours queistiionnaiirei. Speiarman teist was useid to analyzei thei reilatiionshiip beitweiein eiach iindeipeindeint variiablei and thei deipeindeint variiablei (p-valuei <0.05). Result: Speiarman teist reisult was p-valuei = 0.000 for thei associiatiion beitweiein iiron iintakei and MUAC wiith a correilatiion coeiffiiciieint of 0.317. Conclusion: Theirei was a siigniifiicant correilatiion beitweiein iiron iintakei and nutriitiional status baseid on Miid Uppeir Arm Ciircumfeireincei meiasureimeint iin feimalei teieinageirs, Tuban Diistriict.