bluuebunny/crossref_metadata_2025_split huggingface dataset:
Knowledge transfer in family business successions
Authors: Boyd Britta , Royer Susanne , Pei Rong , Zhang Xiaolei 
Published: March 2015

Purpose– Knowledge often is the fundament for strategic competitive advantage. Thus, it is highly relevant to understand better how knowledge is transferred from one generation to the next in family businesses. The purpose of this paper is to link the competitive advantage realisation in family businesses to the success of transferring strategically valuable knowledge in different business environments to the next generation.Design/methodology/approach– Building on the contingency model of family business succession (Royeret al., 2008) knowledge transfer in family businesses from different cultures is investigated in this paper. From a resource-oriented and transaction cost inspired perspective two family businesses with a similar industry background from China and Europe are compared regarding knowledge transfer in the context of family firm succession taking into account the respective transaction atmosphere.Findings– Different successions for two long-lived family firms are illustrated in a systematic fashion: based on the theoretical elements suggested both cases are described to get insights into the usefulness of the theoretical reasoning developed. On the basis of these, the cases are compared with each other and conclusions for both cases are drawn. Implications for theory and practice as well as avenues for future research are sketched.Originality/value– The focus of the current study is to gain more insight into long-lived family businesses by comparing two cases over a period of more than 200 years with regard to strategically relevant resources as well as the underlying transaction atmospheres. Implications for family firms depending on the resource types and transaction atmosphere are discussed.
The absorptive capacity of family firms
Authors: Andersén Jim 
Published: March 2015

Purpose– Absorptive capacity (AC) is a key competitive advantage and is defined as the capacity to absorb knowledge from the environment. Although some studies have examined how various antecedents to AC differ between family firms and non-family firms, no studies have set out to specifically analyze AC in the context of family firms. The purpose of this paper is to discuss the ability of family firms to absorb external knowledge by analyzing the relationship between “familiness” and “AC”.Design/methodology/approach– By reviewing and combining studies on AC and knowledge-management practices of family firms, new insights into the AC of family firms are developed.Findings– It is argued that due to higher levels of social capital, familiness is positively related to the ability to transform and use external knowledge (i.e. realized AC). However, firms with high levels of familiness are likely to be inferior in acquiring and assimilating external knowledge (i.e. potential AC).Originality/value– Although previous studies have analyzed various knowledge-management practices of family firms, no studies have set out to specifically explore how familiness affects various dimensions of AC.
Family business insights: an overview of the literature
Authors: Pounder Paul 
Published: March 2015

Purpose– The purpose of this paper is to investigate how the family business literature has evolved, and to examine the factors influencing family-owned and managed businesses. The paper discusses important patterns in the present literature and new directions for future study.Design/methodology/approach– The research identifies key research topics and methodical approaches to understand family businesses. Insights into the reasoning behind the historic changes and the current direction and trends of the family business literature are also identified.Findings– The findings of this research argues that the main cause of the challenges in running a family business stem from the management of the interrelationship between family concerns and business concerns. Strong leadership and building a culture that accepts continuous change are key success factors.Research limitations/implications– Due to the specific nature of the family business dynamics and decision-making conflict, which can hardly be captured by quantitative studies alone, a promotion of qualitative studies is advisable.Practical implications– This study suggests that understanding the culture surrounding decision making in family business has great value. Characteristics such as aggressiveness, fearlessness and competition are key areas for investigation.Social implications– Overlooking the potential of non-family members for family business leadership can produce sub-optimal choices of successors. Further, the aspiration to change society’s and government’s view of family businesses warrants attention.Originality/value– This review of previous research offers researchers a broader and comprehensive view of the family business, which is inclusive of the challenges, decision making and solutions within the family business structure. Researchers, educators and practitioners will benefit from this paper.
How much does a diabetes out-patient appointment actually cost? An argument for PLICS
Authors: Grant Paul 
Published: March 2015

Purpose– The national tariff system for clinical processes and procedures aims to put a discrete unit cost on clinical activity. Calculating such costs can be subject to a great deal of local variation and interpretation. Given the rising costs of diabetes the purpose of this paper is to ask the question what does a diabetes outpatient appointment in the UK NHS actually cost? This is important in a time of financial austerity and healthcare rationing because it can be difficult to decipher the attribution of costs within the acute hospital setting.Design/methodology/approach– Exploring this question, the author considers the present cost model and analyse in terms of the language of unit model cost; the basic tariff system and how it works in diabetes and looking at internal cost information the author attempts to unbundle the cost to provide a more accurate value for the cost object.Findings– One major finding is that costs and overheads are divided arbitrarily as opposed to being distributed on the basis of measured relative consumption. Alternative costing methods are appraised to demonstrate that a patient level episodic costing approach such as patient level information and costing system (PLICS) which incorporates aspects of activity-based costing (ABC) would be far more appropriate. Using time driven ABC (TDABC), a new patient appointment costs £162 for 30 minutes and a follow-up appointment costs £81 for 15 minutes.Practical implications– PLICS has the added benefit of greater financial and clinical transparency and this goes some way towards the holy grail of greater engagement with the doctors delivering clinical care.Social implications– It would appear that there are different purposes of different costing systems. One can argue that a costing system is there to both contain costs and divide overheads and demonstrate activity. Depending on how data are interpreted costing information can be an agent of enlightenment and behavioural modification for healthcare professionals to show them their direct and indirect costs, their capacity and productivity.Originality/value– Clinicians and health service managers can see from this practical example how the distribution of costs and resources are unfair and can impede the delivery of a service. By using alternative costing methodologies such as ABC not only do the author gets a better reflection of the true cost of the finished consultant episode but is also able to engage clinicians in understanding how costs are generated.
Vertical and horizontal control dilemmas in public hospitals
Authors: Pettersen Inger Johanne , Solstad Elsa 
Published: March 2015

Purpose– The hospital sector in Norway has been continuously reorganized since 2002 and the reforms have created organizations that are functionally/vertically controlled, whereas the production lines are coordinated on a process or a lateral basis. The purpose of this paper is to focus on both the perceived functional vertical control and horizontal controls within and between the local hospitals and the regional administrative levels.Design/methodology/approach– A national survey study, complemented with interviews of some key informants and document studies.Findings– The study shows that the functional and vertical lines of management control are perceived to be operating according to the traditional views of management control. The study indicates that the horizontal tasks are not very well implemented, and we did not find interactive and lateral uses of management control systems for managerial purposes.Practical implications– New control problems arise when services are to be coordinated between autonomous units.Originality/value– The paper focuses on the control problems found within the horizontal, flat relationship between production units in hospitals; new organizational structures have emerged where lateral relations are important, but traditional control practices follow functional, vertical lines.
Impact of the organisational culture on primary care staff members’ intention to engage in research and development
Authors: Morténius Helena , Baigi Amir , Palm Lars , Fridlund Bengt , Björkelund Cecilia , Hedberg Berith 
Published: March 2015

Purpose
– The purpose of this paper is to understand how organisational culture influences the intentions of primary care staff members (PCSM) to engage in research and development (R&D).

Design/methodology/approach
– The participants (n=30) were PCSM employed in a care centre in south-western Sweden. The study had an observational design with an ethnographic approach. The data were collected by means of observations, interviews and analysis of documents.

Findings
– The results revealed the perceptions of PCSM in two domains, research and clinical practice, both of which existed at three different cultural levels: visible (structures and policy), semi-visible (norms and values) and invisible (taken-for-granted attitudes).

Research limitations/implications
– It is difficult to conduct a purely objective ethnographic study because the investigation is controlled by its context. However, it is necessary to highlight and discuss the invisible level to improve understanding of negative attitudes and preconceptions related to the implementation of R&D in the clinical setting.

Practical implications
– By highlighting the invisible level of culture, the management of an organisation has the opportunity to initiate discussion of issues related to concealed norms and values as well as attitudes towards new thinking and change in the primary health context.

Originality/value
– This paper is one of the very few studies to investigate the influence of organisational culture on the intentions of PCSM to engage in R&D.
Using sentiment analysis to review patient satisfaction data located on the internet
Authors: Hopper Anthony M. , Uriyo Maria 
Published: March 2015

Purpose
– The purpose of this paper is to test the usefulness of sentiment analysis and time-to-next-complaint methods in quantifying text-based information located on the internet. As important, the authors demonstrate how managers can use time-to-next-complaint techniques to organize sentiment analysis derived data into useful information, which can be shared with doctors and other staff.

Design/methodology/approach
– The authors used sentiment analysis to review patient feedback for a select group of gynecologists in Virginia. The authors utilized time-to-next-complaint methods along with other techniques to organize this data into meaningful information.

Findings
– The authors demonstrated that sentiment analysis and time-to-next-complaint techniques might be useful tools for healthcare managers who are interested in transforming web-based text into meaningful, quantifiable information.

Research limitations/implications
– This study has several limitations. For one thing, neither the data set nor the techniques the authors used to analyze it will account for biases that resulted from selection issues related to gender, income, and culture, as well as from other socio-demographic concerns. Additionally, the authors lacked key data concerning patient volumes for the targeted physicians. Finally, it may be difficult to convince doctors to consider web-based comments as truthful, thereby preventing healthcare managers from using data located on the internet.

Practical implications
– The report illustrates some of the ways in which healthcare administrators can utilize sentiment analysis, along with time-to-next-complaint techniques, to mine web-based, patient comments for meaningful information.

Originality/value
– The paper is one of the first to illustrate ways in which administrators at clinics and physicians’ offices can utilize sentiment analysis and time-to-next-complaint methods to analyze web-based patient comments.
Data visualization as a communication tool
Authors: Archambault Susan Gardner , Helouvry Joanne , Strohl Bonnie , Williams Ginger 
Published: March 2015

Purpose
– This paper aims to provide a framework for thinking about meaningful data visualization in ways that can be applied to routine statistics collected by libraries.

Design/methodology/approach
– An overview of common data display methods is provided, with an emphasis on tables, scatter plots, line charts, bar charts, histograms, pie charts and infographics. Research on “best practices” in data visualization design is presented; also provided is a comparison of free online data visualization tools.

Findings
– Different data display methods are best suited for different quantitative relationships. There are rules to follow for optimal data visualization design. Ten free online data visualization tools are recommended by the authors.

Originality/value
– Evidence-based libraries collect and use data to affect change and to support departmental and institutional accreditation standards. Proper data visualization allows libraries to communicate their message in a more compelling and interesting way, while assisting in the understanding of complex data.
Utilizing a time-to-shelf study to start a conversation on change
Authors: Gibson Sally 
Published: March 2015

Purpose
– The purpose of this paper is to show the value of benchmarking organizational performance in order to enable conversations about workflow analysis and potential changes.

Design/methodology/approach
– Data from a time-to-shelf study are compared to literature describing similar studies at other academic libraries which enable the decision-making process for a new workflow.

Findings
– The results of a time-to-shelf study necessitated a change in workflow. This paper examines how the data enabled staff to agree to changes and supported the decision-making process.

Originality/value
– This paper examines the impact of evidence-based decision making on the performance and workflow of a technical services department.
Building holistic and agile collection development and assessment
Authors: Duncan Cheri Jeanette , O'Gara Genya Morgan 
Published: March 2015

Purpose
– The purpose of this paper is to examine the development of a flexible collections assessment rubric comprised of a suite of tools for more consistently and effectively evaluating and expressing a holistic value of library collections to a variety of constituents, from administrators to faculty and students, with particular emphasis to the use of data already being collected at libraries to “take the temperature” of how responsive collections are in supporting institutional goals.

Design/methodology/approach
– Using a literature review, internal and external conversations, several collections pilot projects, and a variety of other investigative mechanisms, this paper explores methods for creating a more flexible, holistic collection development and assessment model using both qualitative and quantitative data.

Findings
– The products of scholarship that academic libraries include in their collections are expanding exponentially and range from journals and monographs in all formats, to databases, data sets, digital text and images, streaming media, visualizations and animations. Content is also being shared in new ways and on a variety of platforms. Yet the framework for evaluating this new landscape of scholarly output is in its infancy. So, how do libraries develop and assess collections in a consistent, holistic, yet agile, manner? Libraries must employ a variety of mechanisms to ensure this goal, while remaining flexible in adapting to the shifting collections environment.

Originality/value
– In so much as the authors are aware, this is the first paper to examine an agile, holistic approach to collections using both qualitative and quantitative data.
Steatocystoma multiplex with hair shaft abnormalities
Authors: Pietrzak Aldona , Bartosinska Joanna , Filip Agata A. , Rakowska Adriana , Adamczyk Michal , Szumilo Justyna , Kanitakis Jean 
Published: March 2015

AbstractSteatocystoma multiplex (SM) is an unusual benign disorder of the pilosebaceous duct characterized by multiple cysts with little or no nail and hair involvement. We report a 30‐year‐old woman with multiple cystic nodules located on the neck, axillae and forearms as well as patchy scalp alopecia. Histopathological examination of the lesions was diagnostic of SM. Trichoscopy revealed pili torti and pili canaliculi. This patient represents an unusual clinical presentation of SM because of the presence of hair abnormalities.
Sebaceous carcinoma in association with actinic keratosis: A report of two cases with an immunohistochemical study
Authors: Misago Noriyuki , Kuwashiro Maki , Tsuruta Noriko , Narisawa Yutaka 
Published: March 2015

AbstractWe report two cases of sebaceous carcinoma associated with actinic keratosis (AK) with an immunohistochemical study, which suggests the possibility that sebaceous carcinoma really does develop within AK. Case 1 had sebaceous carcinoma arising within the atrophic type AK and case 2 had sebaceous carcinoma associated with bowenoid AK in the periphery and some parts of the overlying epidermis of the lesion.
Rs4948496 within ARID5B gene is associated with clinical features of systemic lupus erythematosus in the Chinese Han population
Authors: Jiang Long , Wu Jianping , Li Weiran , Du Juan , Wang Wenjun , Zhu Zhengwei , Gao Jinping , Sheng Yujun , Yin Xianyong , Zheng Xiaodong , Li Hui , Li Yang , Meng Li , Fan Xing , Liu Shengxiu , Zeng Ming , Wang Zaixing , Cui Yong , Tang Huayang , Sun Liangdan , Yang Sen , Zhang Xuejun 
Published: March 2015

AbstractIn our previous meta‐analysis of genome‐wide association study, we identified the single nucleotide polymorphism (SNP) rs4948496 (P = 5.1 × 10−11, odds ratio [OR] = 0.85) within the ARID5B gene associated with systemic lupus erythematosus (SLE) in a Chinese population. To investigate its association with disease subphenotypes, we further analyzed the genotype data of rs4948496 in 4348 cases and 6679 controls from our previous meta‐analysis and an independent replication cohort in this study. The SNP rs4948496 was significantly associated with SLE (P = 1.61 × 10−5, OR = 0.88, 95% confidence interval [CI] = 0.83–0.93) in our group. In case‐only study, the genotype of rs4948496 was associated with antinuclear antibodies (P = 0.03, OR = 0.81, 95% CI = 0.68–0.98) and anti‐RNP (P = 0.03, OR = 0.86, 95% CI = 0.76–0.99). This study showed that rs4948496 in ARID5B is associated with several subphenotypes of SLE and this gene may cause the complicacy of clinical features.
Lamellar ichthyosis with pseudoexon activation in the transglutaminase 1 gene
Authors: Suga Yasushi , Tsuda Tatsuya , Nagai Makoto , Sakaguchi Yoshiko , Jitsukawa Orie , Yamamoto Masaaki , Hitomi Kiyotaka , Yamanishi Kiyofumi 
Published: March 2015

AbstractWe report a case of a 12‐year‐old boy who was born as a collodion baby after which thick scales developed on his entire body surface. His younger brother showed a similar skin condition. Arcuate‐shaped, large, brownish scales covered his face with ectropion. His lower legs were also covered with larger thick, brownish, plate‐like scales, but other areas were covered with smaller scales. Next‐generation sequencing for exons and splice sites detected a stop‐gain TGM1 mutation leading to p.R71* in transglutaminase 1 (TG1). Another mutation identified was a cryptic mutation in intron 3 that activated a pseudoexon, which was detected by RNA‐based analysis of hair bulbs. The deep intronic mutation caused another truncation mutation, p.N171Tfs*45, in TG1. An in situ TG1 assay demonstrated that TG1 activity was totally lost in this case. Thus, we conclude that the severe phenotype of the patient developed due to those novel compound heterozygous null truncation mutations in TGM1.
Refractory case of adrenergic urticaria successfully treated with clotiazepam
Authors: Kawakami Yukari , Gokita Mari , Fukunaga Atsushi , Nishigori Chikako 
Published: March 2015

AbstractAdrenergic urticaria (AU) is a rare type of stress‐induced physical urticaria characterized by widespread pruritic urticarial papules. Diagnosis can be made by i.d. injection of adrenaline or noradrenaline, which produces the characteristic rash. Although the lesions of AU typically respond to beta‐blockers such as propranolol, the therapeutic options for AU are limited. Here, we report a case of AU that was resistant to beta‐blockers and successfully treated with clotiazepam. The clinical picture of AU resembles that of cholinergic urticaria (CU), however, positive noradrenaline test and negative acetylcholine skin test were useful for the differential diagnosis of AU and CU. Although his symptoms were resistant to several therapeutic methods including olopatadine (H1 antagonist), lafutidine (H2 antagonist) and propranolol, the severity and frequency of his attacks and his subjective symptoms were reduced by oral clotiazepam, an anxiolytic benzodiazepine. Dermatologists should be aware that anxiolytic benzodiazepines may be a therapeutic option in AU.
Interactome analysis of herpes simplex virus 1 envelope glycoprotein H
Authors: Hirohata Yoshitaka , Kato Akihisa , Oyama Masaaki , Kozuka‐Hata Hiroko , Koyanagi Naoto , Arii Jun , Kawaguchi Yasushi 
Published: March 2015

ABSTRACTHerpes simplex virus 1 (HSV‐1) envelope glycoprotein H (gH) is important for viral entry into cells and nuclear egress of nucleocapsids. To clarify additional novel roles of gH during HSV‐1 replication, host cell proteins that interact with gH were screened for by tandem affinity purification coupled with mass spectrometry‐based proteomics in 293T cells transiently expressing gH. This screen identified 123 host cell proteins as potential gH interactors. Of these proteins, general control nonderepressive‐1 (GCN1), a trans‐acting positive effector of GCN2 kinase that regulates phosphorylation of the α subunit of translation initiation factor 2 (eIF2α), was subsequently confirmed to interact with gH in HSV‐1‐infected cells. eIF2α phosphorylation is known to downregulate protein synthesis, and various viruses have evolved mechanisms to prevent the accumulation of phosphorylated eIF2α in infected cells. Here, it was shown that GCN1 knockdown reduces phosphorylation of eIF2α in HSV‐1‐infected cells and that the gH‐null mutation increases eIF2α in HSV‐1‐infected cells, whereas gH overexpression in the absence of other HSV‐1 proteins reduces eIF2α phosphorylation. These findings suggest that GCN1 can regulate eIF2α phosphorylation in HSV‐1‐infected cells and that the GCN1‐binding viral partner gH is necessary and sufficient to prevent the accumulation of phosphorylated eIF2α. Our database of 123 host cell proteins potentially interacting with gH will be useful for future studies aimed at unveiling further novel functions of gH and the roles of cellular proteins in HSV‐1‐infected cells.