bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Synthesis and Antifungal Activity of Some Novel (E)‐2,3‐Dihydro‐3‐[(phenylamino)methylene]‐4H‐1‐benzothiopyran‐4‐ones (III).
Authors: Liu Xiao‐Ming , Yang Geng‐Liang , Song Ya‐Li , Liu Jie‐Jie , Wang Yang , Zhang Dong‐Nuan 
Published: September 2013

AbstractTitle compounds (IIIe) and (IIIf) display similar or slighter higher inhibitory activity against Candida albicans than the standard Fluconazole.
ChemInform Abstract: Stereoselective Synthesis of Polyfunctionalized Nitrothianes: Enhancement of Stereoselectivity by Microwaves.
Authors: Vinosha Beermohamed , Renuga Subbiah , Perumal Subbu , Muthiah Packianathan Thomas , Thanigaimani Kaliyaperumal 
Published: September 2013

AbstractMichael addition of nitromethane to (Z,Z)‐thiobis(enones) (I) under thermal conditions affords a diastereomeric mixture of the desired nitrothiopyran derivatives.
ChemInform Abstract: A Facile Chemo‐, Regio‐ and Stereoselective Synthesis and Cholinesterase Inhibitory Activity of Spirooxindole—Pyrrolizine—Piperidine Hybrids.
Authors: Kia Yalda , Osman Hasnah , Kumar Raju Suresh , Murugaiyah Vikneswaran , Basiri Alireza , Perumal Subbu , Razak Ibrahim Abdul 
Published: September 2013

AbstractNew hybrids (IVd)—(IVg) display acetylcholinesterase inhibitory potential comparable to the standard drug galantamine with (IVe) as the most active one.
ChemInform Abstract: Bifunctional Chiral Urea Catalyzed Highly Enantioselective Michael Addition of Cyclic 1,3‐Dicarbonyl Compounds to 2‐Enoylpyridine.
Authors: Molleti Nagaraju , Allu Suresh , Ray Sumit K. , Singh Vinod K. 
Published: September 2013

AbstractThe title process provides Michael adducts which are acetylated to yield products of type (IV), (VII), and (IX) generally with high levels of enantioselectivity.
ChemInform Abstract: Chiral Pool Synthesis of N‐Cbz‐cis‐(3R,4R)‐3‐methylamino‐4‐methylpiperidine from L‐Malic Acids.
Authors: Hao Bao‐Yu , Liu Jin‐Qiang , Zhang Wei‐Han , Chen Xin‐Zhi 
Published: September 2013

AbstractTitle compound (II), key building block for the synthesis of the first‐in‐class Janas tyrosine kinase inhibitor CP‐690,550, is prepared from cheap raw materials using established transformations.
ChemInform Abstract: Synthesis and Fluorescent Properties of 2‐Styryl‐6,7‐difluoro‐8‐hydroxyquinoline and Its Zn(II) Complex.
Authors: Nosova Emiliya V. , Stupina Tatyana V. , Lipunova Galina N. , Charushin Valery N. 
Published: September 2013

AbstractA new synthetic approach to the title compound (IV) is presented which is the key intermediate for various further transformations.
ChemInform Abstract: Transition‐Metal‐Free Carbofluorination of TBS‐Protected Nitrogen‐Containing Cyclic Enynols: Synthesis of Fluorinated Azabicycles.
Authors: Yeh Ming‐Chang P. , Liang Chia‐Jung , Huang Tzu‐Lin , Hsu Hsiao‐Ju , Tsau Yu‐Shuo 
Published: September 2013

AbstractThe new method provides easy access to fluorinated azabicycles within short reaction times under metal‐free conditions.
ChemInform Abstract: ZnCl2‐Catalyzed Three‐Component Domino Reactions for the Synthesis of Pyrano[3,2‐c]quinolin‐5(6H)‐ones.
Authors: Gunasekaran Pethaiah , Prasanna Pitchaimani , Perumal Subbu , Almansour Abdulrahman I. 
Published: September 2013

AbstractA facile one‐pot protocol is developed for the condensation/Michael addition/annulation sequence which creates 2 C—C bonds and one C—O bond in a single operation.
ChemInform Abstract: One‐Pot Synthesis and X‐Ray Structure of New, Stable Tetrahydropyrrolo[1,2‐a][1,10]Phenanthrolines with Four Diastereoisomeric Centers.
Authors: Heydari Reza , Tahamipour Batool , Torbati Niloofar Akbarzadeh , Graiff Claudia , Ziyaadini Morteza 
Published: September 2013

AbstractThe title compounds (IV) are obtained by a domino‐Knoevenagel cyclization of phenanthrolinium N‐ylides (I) with ethyl cyanoacetate and aromatic aldehydes under mild reaction conditions.
ChemInform Abstract: Simple, Catalyst‐Free, One‐Pot Procedure for the Synthesis of 2‐Amino‐3‐cyano‐1,4,5,6‐tetrahydropyrano[3,2‐c]quinolin‐5‐one Derivatives
Authors: Yao Meng‐Jian , Guan Zhi , He Yan‐Hong 
Published: September 2013

Abstractby three‐component one‐pot reaction of 4‐hydroxyquinolin‐2(1H)‐one (I), malononitrile, and various aldehydes
ChemInform Abstract: A General Method to Diverse Cinnolines and Cinnolinium Salts.
Authors: Zhao Dongbing , Wu Qian , Huang Xiaolei , Song Feijie , Lv Taiyong , You Jingsong 
Published: September 2013

AbstractA highly efficient and general method for the preparation of cinnolines, cinnolinium salts, and polycyclic cinnolinium salts through rhodium(III)‐catalyzed oxidative C—H activation/cyclization of azo compounds with alkynes is developed.
ChemInform Abstract: Efficient Access to 1,4‐Benzothiazine: Palladium‐Catalyzed Double C—S Bond Formation Using Na2S2O3 as Sulfurating Reagent.
Authors: Qiao Zongjun , Liu Hui , Xiao Xiao , Fu Yana , Wei Jianpeng , Li Yuxue , Jiang Xuefeng 
Published: September 2013

AbstractA novel Pd‐catalyzed double C—S bond formation coupling reaction is developed.
ChemInform Abstract: [Omim][NO3], a Green and Base‐Free Medium for One‐Pot Synthesis of Benzothiazinones at Room Temperature.
Authors: Sharifi Ali , Abaee M. Saeed , Rouzgard Mahdiyeh , Mirzaei Mojtaba 
Published: September 2013

AbstractThe title compounds (III) and (V) are obtained by a general and efficient one‐pot reaction of 2‐aminothiophenols (I) with 2‐bromoalkanoates (II) or (IV) resp., without any catalyst, base, or additive.
ChemInform Abstract: Sono‐Transition‐Metal Catalysis of One‐Pot Three‐Step Synthesis of Glycosyl‐1,2,3‐triazoles.
Authors: Driowya Mohsine , Bougrin Khalid , Benhida Rachid 
Published: September 2013

AbstractAn efficient and eco‐friendly three‐step one‐pot procedure for the synthesis of a new series of glycosyl triazoles is developed using ultrasonic activation and iron‐copper dual catalysis.
ChemInform Abstract: Zearalenone Mimics: Synthesis of (E)‐6‐(1‐Alkenyl)‐Substituted β‐Resorcylic Acid Esters.
Authors: Mikula Hannes , Hametner Christian , Froehlich Johannes 
Published: September 2013

AbstractAlternative approaches to the synthesis of unsaturated substituted β‐resorcylic acid esters as mimics for the mycotoxin zearalenone are developed using ortho‐directed lithiation reactions as key step.
ChemInform Abstract: Synthetic Prodigiosenes and the Influence of C‐Ring Substitution on DNA Cleavage, Transmembrane Chloride Transport and Basicity.
Authors: Rastogi Soumya , Marchal Estelle , Uddin Imam , Groves Brandon , Colpitts Julie , McFarland Sherri A. , Davis Jeffery T. , Thompson Alison 
Published: September 2013

AbstractSeveral analogues of the tripyrrolic red pigment prodigiosin [cf.
ChemInform Abstract: Sustainable Practices in Medicinal Chemistry: Current State and Future Directions
Authors: Bryan Marian C. , Dillon Barry , Hamann Lawrence G. , Hughes Gregory J. , Kopach Michael E. , Peterson Emily A. , Pourashraf Mehrnaz , Raheem Izzat , Richardson Paul , Richter Daniel , et al. et al. 
Published: September 2013

AbstractReview: 72 refs.
Synthesis and Pharmacological Evaluation of a series of the Agomelatine Analogues as Melatonin MT1/MT2 Agonist and 5‐HT2C Antagonist
Authors: Ettaoussi Mohamed , Sabaouni Ahmed , Pérès Basile , Landagaray Elodie , Nosjean Olivier , Boutin Jean A. , Caignard Daniel‐Henri , Delagrange Philippe , Berthelot Pascal , Yous Saïd 
Published: September 2013

AbstractAgomelatine is a naphthalenic analogue of melatonin that is in clinical use for the treatment of major depressive disorders. Interestingly, while agomelatine exhibits potent affinity for melatonin receptors, it binds with only moderate affinity to the serotonin 5‐HT2C receptor. Optimization of agomelatine toward this target could further potentiate its clinical efficacy. To explore this hypothesis and to access derivatives in which a key point of agomelatine metabolism is blocked, a series of naphthalenic derivatives was designed and synthesized as novel analogues of agomelatine. Most of the prepared compounds exhibited good binding affinity at the melatonin MT1 and MT2 receptor subtypes. Two compounds, an acetamide and an acrylamide derivative, exhibited good binding affinities at both the human melatonin (MT) receptors and the serotonin 5‐HT2C receptor subtype, with pKi values of 7.96 and 7.95 against MT1, 7.86 and 8.68 against MT2, and 6.64 and 6.44 against 5‐HT2C, respectively.
Improving the scalability of a symmetric iterative eigensolver for multi‐core platforms
Authors: Aktulga Hasan Metin , Yang Chao , Ng Esmond G. , Maris Pieter , Vary James P. 
Published: September 2013

SUMMARYWe describe an efficient and scalable symmetric iterative eigensolver developed for distributed memory multi‐core platforms. We achieve over 80% parallel efficiency by major reductions in communication overheads for the sparse matrix‐vector multiplication and basis orthogonalization tasks. We show that the scalability of the solver is significantly improved compared to an earlier version, after we carefully reorganize the computational tasks and map them to processing units in a way that exploits the network topology. We discuss the advantage of using a hybrid OpenMP/MPI programming model to implement such a solver. We also present strategies for hiding communication on a multi‐core platform. We demonstrate the effectiveness of these techniques by reporting the performance improvements achieved when we apply our solver to large‐scale eigenvalue problems arising in nuclear structure calculations. Because sparse matrix‐vector multiplication and inner product computation constitute the main kernels in most iterative methods, our ideas are applicable in general to the solution of problems involving large‐scale symmetric sparse matrices with irregular sparsity patterns. Copyright © 2013 John Wiley & Sons, Ltd.
Drinking Water Purification by Electrosynthesis of Hydrogen Peroxide in a Power‐Producing PEM Fuel Cell
Authors: Li Winton , Bonakdarpour Arman , Gyenge Előd , Wilkinson David P. 
Published: September 2013

AbstractThe industrial anthraquinone auto‐oxidation process produces most of the world’s supply of hydrogen peroxide. For applications that require small amounts of H2O2 or have economically difficult transportation means, an alternate, on‐site H2O2 production method is needed. Advanced drinking water purification technologies use neutral‐pH H2O2 in combination with UV treatment to reach the desired water purity targets. To produce neutral H2O2 on‐site and on‐demand for drinking water purification, the electroreduction of oxygen at the cathode of a proton exchange membrane (PEM) fuel cell operated in either electrolysis (power consuming) or fuel cell (power generating) mode could be a possible solution. The work presented here focuses on the H2/O2 fuel cell mode to produce H2O2. The fuel cell reactor is operated with a continuous flow of carrier water through the cathode to remove the product H2O2. The impact of the cobalt–carbon composite cathode catalyst loading, Teflon content in the cathode gas diffusion layer, and cathode carrier water flowrate on the production of H2O2 are examined. H2O2 production rates of up to 200 μmol h−1 cmgeometric −2 are achieved using a continuous flow of carrier water operating at 30 % current efficiency. Operation times of more than 24 h have shown consistent H2O2 and power production, with no degradation of the cobalt catalyst.
Cu/MgAl2O4 as Bifunctional Catalyst for Aldol Condensation of 5‐Hydroxymethylfurfural and Selective Transfer Hydrogenation
Authors: Pupovac Kristina , Palkovits Regina 
Published: September 2013

AbstractCopper supported on mesoporous magnesium aluminate has been prepared as noble‐metal‐free solid catalyst for aldol condensation of 5‐hydroxymethylfurfural with acetone, followed by hydrogenation of the aldol condensation products. The investigated mesoporous spinels possess high activity as solid‐base catalysts. Magnesium aluminate exhibits superior activity compared to zinc and cobalt‐based aluminates, reaching full conversion and up to 81 % yield of the 1:1 aldol product. The high activity can be correlated to a higher concentration of basic surface sites on magnesium aluminate. Applying continuous regeneration, the catalysts can be recycled without loss of activity. Focusing on the subsequent hydrogenation of aldol condensation products, Cu/MgAl2O4 allows a selective hydrogenation and CO bond cleavage, delivering 3‐hydroxybutyl‐5‐methylfuran as the main product with up to 84 % selectivity avoiding ring saturation. Analysis of the hydrogenation activity reveals that the reaction proceeds in the following order: CC>CO>CO cleavage>ring hydrogenation. Comparable activity and selectivity can be also achieved utilizing 2‐propanol as solvent in the transfer hydrogenation, providing the possibility for partial recycling of acetone and optimization of the hydrogen management.
Synthesis of n‐port resistive networks containing 2n terminals
Authors: Chen Michael Z. Q. , Wang Kai , Yin Minghui , Li Chanying , Zuo Zhiqiang , Chen Guanrong 
Published: September 2013

AbstractThis paper is concerned with the realizability problem of n‐port resistive networks that contain 2n terminals. A necessary and sufficient condition for any real symmetric matrix to be realizable as the admittance of an n‐port resistive network containing 2n terminals is obtained. This condition is based on the existence of a parameter matrix. Furthermore, the values of the elements are expressed in terms of the entries of the admittance matrix and the parameter matrix. Finally, a numerical example is used to illustrate the results. Copyright © 2013 John Wiley & Sons, Ltd.
High‐capacity soliton transmission for indoor and outdoor communications using integrated ring resonators
Authors: Amiri I. S. , Alavi S. E. , Ali J. 
Published: September 2013

SUMMARYA system consisting of a series of microring resonators, incorporating an add/drop system, is presented in order to create ultra‐short spatial and temporal single and multisoliton pulses, which can be used for indoor and outdoor optical communications. Chaotic noise can be generated by a bright soliton pulse propagating inside a nonlinear microring resonator system. The results obtained show that a single temporal and spatial soliton pulse, with full width at half maximums of 75 fs, 80 fs, 700 fs, 4.4 ps, and 0.30 nm, can be generated. The add/drop system can be used to generate a high number of ultra‐short soliton pulses in the ranges of nanometer/second and picometer/second. The simulated multisolitons have full width at half maximums of 16 ps, 20 pm, 130 ps, and 35 pm and free spectrum ranges of 500 ps, 0.57 nm, 3.5 ns, and 1.4 nm, respectively. The multisolitons generated at the drop port can be used in indoor optical communications, where the ultra‐short pulses with a variety of central wavelengths (from λ = 1550 to λ = 1560) from the through port can be multiplexed‐demultiplexed along an optical fiber with a length of 50 km. The filtered signals can be obtained at the end of the transmission link used for optical outdoor communications. Copyright © 2013 John Wiley & Sons, Ltd.
Angiogenic Biomaterials to Promote Tissue Vascularization and Integration
Authors: Wells Laura A. , Valic Michael S. , Lisovsky Alexandra , Sefton Michael V. 
Published: September 2013

AbstractRobert Langer’s work with Judah Folkman brought angiogenesis into the spotlight and herein we focus on an offshoot of this work – biomaterial‐driven therapeutic angiogenesis. Angiogenic biomaterials are expected to improve vascularization and integration in tissue engineering, wound healing and medical device applications. This review focuses on therapeutic methacrylic acid copolymers, highlighting some new approaches to use these materials. Such copolymers require no biological components (drugs or cells) to promote in vivo vascularization; they are therapeutic polymers.
Domestic Violence: A case of the Disappearing Victim?†
Authors: McIntyre Deborah 
Published: September 2013

ABSTRACTThis article examines the current theoretical constructions of the phenomenon of domestic violence, and their therapeutic implications. It attempts to draw out the latent socio‐political content of that theorizing, arguing that throughout the various approaches there is a consistent de‐emphasizing of the woman's position as victim of the violent act. An alternative analysis is offered, one which recognizes gender inequality as fundamental to any understanding of domestic violence, and the implications for therapeutic work in this area are briefly explored.
Marital Therapy and Feminism
Authors: Chapman Jane , Park Sue 
Published: September 2013

ABSTRACTThe authors examine first the meaning ascribed to gender behaviour and the impact this has on couples' struggle to evolve a marital structure that can equitably meet their needs. The roles played by counsellors who inadvertently reinforce sex‐role stereotyping in their counselling is also described and case‐discussion in literature where sexism prevails will be presented. Alternative ways of helping couples discover their own fit without appealing to gender behaviour as a structural social tool will be developed. Attention is drawn to the necessity for counsellors to first question their own values about gender behaviour, without succumbing to social definitions.
Home Visits in Crisis Situations — Analysis of Context and Suggestions for Intervention
Authors: Viaro Maurizio , Peruzzi Pio , Roberts E. 
Published: September 2013

AbstractThe authors describe the characteristics inherent in a home visit in crisis situations. They form a hypothesis on a particular kind of relationship which develops between the one who asks for the visit and the Institution. By means of a description of a clinical case they show various methodologies which re‐define the context so as to permit the therapist to take control of the relationship. 16 cases have been treated according to this hypothesis over three years. However the manoeuvres used each time have been continually modified and adjusted. The proposed model represents an attempt at unification of the most effective manoeuvres in a coherent strategy.
Management of Night‐Waking in Young Children
Authors: Seymour Frederick W. , Bayfield Gay , Brock Phyllis , During Mary 
Published: September 2013

AbstractRegular waking at night is one of the most common problems encountered by parents of young children. In a family counselling programme in Auckland, a night‐waking programme has been used with 208 children referred during a two year period. The programme involved organized bed‐time routines, procedures for settling the child and non‐reward of crying, calling out and getting out of bed. Programme introduction was followed by daily phone calls to parents in which appropriate parent behaviours were prompted and reinforced. Further face to face sessions were held after one week and then if needed. Parent reports show high rates of parent implementation of procedures and rapid change of child sleep behaviour with improvements being maintained at follow up. In a survey of 48 of the parents, positive changes in the daytime behaviour of children were reported as coinciding with improved sleep habits. Also there was an absence of negative side effects, and generally, parent satisfaction with the programme was high.
A Strategic Approach to an Extreme Feeding Problem
Authors: Epston David , Brock Phyllis 
Published: September 2013

AbstractThis paper describes the dramatic resolution of a refractory feeding problem of an eighteen month old boy. He had spent 199 days in hospital prior to treatment and none following this, except for a brief period for a tonsillectomy. He has regained his developmental pace. The authors have attempted to isolate their hypotheses and the interventions derived from them. The parents reflection on the therapy, four months after the first session, provides a commentary on our commentary.
Biological and psychological predictors of visceral pain sensitivity in healthy premenopausal women
Authors: Lacourt T.E. , Houtveen J.H. , Doornen L.J.P. , Benson S. , Grigoleit J.‐S. , Cesko E. , Elsenbruch S. 
Published: September 2013

AbstractBackgroundFactors that are associated with pain perception remain incompletely understood, especially in the visceral pain field. Therefore, the current study aimed to investigate possible psychological and biological predictors of visceral pain sensitivity in healthy subjects.MethodsIn a sample of 59 healthy premenopausal female subjects on hormonal contraceptives, measures of gastrointestinal (GI) symptoms in daily life, trait and state anxiety, depression, serum cortisol concentrations and serum levels of interleukin‐6 (IL‐6) were obtained, followed by assessment of rectal distension pain sensitivity measures (i.e., rectal distension sensory threshold, pain threshold and pain ratings for discrete rectal distension stimuli).ResultsRegression analyses showed that more GI symptoms in daily life predicted a lower pain threshold. Higher levels of state anxiety predicted a lower pain threshold. Higher cortisol concentrations predicted lower pain ratings. IL‐6 was positively related to GI symptoms but was a non‐significant predictor of pain threshold in the multiple regression analysis.ConclusionsSimilar to findings in patients with functional GI symptoms, we showed that subclinical GI symptoms predict visceral pain sensitivity. In line with somatic pain findings, state but not trait anxiety was found to predict visceral pain sensitivity. Our finding on serum cortisol as positive predictor of pain sensitivity might be interpreted in light of immunosuppressive effects of cortisol. Our finding on the role of IL‐6 in GI symptoms is promising for understanding GI complaints in patients and needs further investigation.
Effect and Possible Mechanism of Network Between MicroRNAs and RUNX2 Gene on Human Dental Follicle Cells
Authors: Chen Pei , Wei Dixin , Xie Baoyi , Ni Jia , Xuan Dongying , Zhang Jincai 
Published: September 2013

ABSTRACTTo investigate whether crosstalk between RUNX2 and miRNAs is involved in tooth eruption regulated by dental follicle cells (DFCs) and the possible molecular mechanism. Blood samples and embedded dental follicles were collected from patients with cleidocranial dysplasia, and RUNX2 gene mutations were analyzed, then RUNX2+/m DFCs were isolated and identified. The characteristics of RUNX2+/m DFCs were analyzed. The differential expression of miRNAs was detected between the RUNX2+/m DFCs and RUNX2+/+ DFCs by microarray, and target genes were predicted by miRGen. miR‐146a was chosen for further investigation, and its effects in DFCs were analyzed by transfecting its mimics and inhibitors, and expression of genes involved in tooth eruption were detected. A novel insertion mutation (c.309_310insTG) of RUNX2 gene was identified which had an effect on the characteristics of DFCs. Compared with the RUNX2+/+ DFCs, there were 69 microRNAs more than twofold up‐regulated and 54 microRNAs more than twofold down‐regulated in the RUNX2+/m DFCs. Among these, miR‐146a decreased significantly in RUNX2+/m DFCs, and expression of RUNX2, CSF‐1, EGFR, and OPG was significantly altered when miR‐146a was overexpressed or inhibited. RUNX2 gene mutation contributes to the characteristic change of DFCs, and the crosstalk between RUNX2 gene and miRNAs may be one of the key regulatory mechanisms of differentiation of DFCs. J. Cell. Biochem. 115: 340–348, 2014. © 2013 Wiley Periodicals, Inc.