bluuebunny/crossref_metadata_2025_split huggingface dataset:
Frontal and occipital brain glutathione levels are unchanged in autistic adults
Authors: Pereira Andreia C. , Leonard Alison , Velthuis Hester , Wong Nichol M. L. , Ponteduro Francesca M. , Dimitrov Mihail , Ellis Claire L. , Kowalewski Lukasz , Lythgoe David J. , Rotaru Diana-Georgina , Edden Richard A. E. , Ivin Glynis , Pretzsch Charlotte M. , Daly Eileen , Murphy Declan G. M. , McAlonan Gráinne M. 
Published: August 2024

Background
The neurobiological underpinnings of Autism Spectrum Disorder (ASD) are diverse and likely multifactorial. One possible mechanism is increased oxidative stress leading to altered neurodevelopment and brain function. However, this hypothesis has mostly been tested in post-mortem studies. So far, available in vivo studies in autistic individuals have reported no differences in glutathione (GSH) levels in frontal, occipital, and subcortical regions. However, these studies were limited by the technically challenging quantification of GSH, the main brain antioxidant molecule. This study aimed to overcome previous studies’ limitations by using a GSH-tailored spectroscopy sequence and optimised quantification methodology to provide clarity on GSH levels in autistic adults.

Methods
We used spectral editing proton-magnetic resonance spectroscopy (1H-MRS) combined with linear combination model fitting to quantify GSH in the dorsomedial prefrontal cortex (DMPFC) and medial occipital cortex (mOCC) of autistic and non-autistic adults (male and female). We compared GSH levels between groups. We also examined correlations between GSH and current autism symptoms, measured using the Autism Quotient (AQ).

Results
Data were available from 31 adult autistic participants (24 males, 7 females) and 40 non-autistic participants (21 males, 16 females); the largest sample to date. The GSH levels did not differ between groups in either region. No correlations with AQ were observed.

Conclusion
GSH levels as measured using 1H-MRS are unaltered in the DMPFC and mOCC regions of autistic adults, suggesting that oxidative stress in these cortical regions is not a marked neurobiological signature of ASD.
Genetic structure of black soldier flies in northern Iran
Authors: Boukan Afrooz , Nozari Jamasb , Naseri Karimi Nazanin , Talebzadeh Fahimeh , Pahlavan Yali Katayoun , Oshaghi Mohammad Ali 
Published: August 2024

Background
The black soldier fly (BSF), Hermetia illucens, is known for nutrient-recycling through the bioconversion of organic waste into protein-rich insect larvae that can be processed into an animal feed ingredient. However, information on species distribution and its genetic structure in Iran is scarce.

Methods and results
We directed a survey on the Caspian Sea coast, with a reconstructing demographic relationships study using two parts of mitochondrial cytochrome C oxidase 1 (COI) gene (barcode and 3’ end regions) and nuclear internal transcribed spacer 2 (ITS2) to identify BSF’ genetic diversity in retrospect to the global diversity and the potential origin of the Iranian BSF population. Larvae and adults were recovered from highly decomposed poultry manure, in May 2020. Sequence analysis of both regions of COI gene (about 1500 bp) revealed a single haplotype, identical to that of haplotype C, a worldwide commercial strain originated from Nearctic, Palearctic, or African biogeographic regions. However, the ITS2 locus was confirmed to be invariable across samples from diverse biogeographic regions.

Conclusion
The results proved the presence of BSF in north of Iran. However, it is not possible to determine with certainty when and where this species first established in Iran, and they have likely been released to nature due to the existence of companies importing and breeding such flies. Due to heavy international trading, the introduction and settlement of this fly in the southern coasts of the country is highly suggested.
Association between nocturia and serum albumin in the U.S. adults from NHANES 2005–2012
Authors: Jia Yangtao , Yang Fangzheng , Dong Xinke , Zhou Libin , Long Huimin 
Published: August 2024

Background
Nocturia, a prevalent chronic condition, impacts individuals’ quality of life but remains underexplored. This study aimed to assess the association between serum albumin levels and nocturia.

Methods
Based on the analysis of the National Health and Nutrition Examination Survey (NHANES) database (2005–2012), our study included a total of 6345 adults (≥20 years old). Nocturia was defined as ≥2 nocturnal voiding episodes. Logistic regression and smooth curve fitting analyzed the linear and nonlinear correlations between serum albumin and nocturia, with subgroup analysis.

Results
Among 6345 participants, 1821 (28.7%) experienced nocturia. Logistic regression analysis revealed a linear negative correlation between serum albumin and nocturia risk (OR = 0.9549, 95% CI = 0.9280 ~ 0.9827, P = 0.002). Even after quartile division of serum albumin concentration, this correlation persisted within each group, and a smooth curve fitting validated the nonlinear negative correlation between the two. Subgroup analysis further demonstrated significant impacts of body mass index (BMI), alcohol consumption, and age on this association.

Conclusion
This cross-sectional study indicated that higher serum albumin levels were associated with a reduced risk of nocturia in U.S. adults aged 20 and older, highlighting the importance of serum albumin in the prevention and treatment of nocturia and providing clinical guidance.
Estratégia de manutenção em usina de açúcar e álcool com duas linhas de moagem utilizando a engenharia de confiabilidade
Authors: Ferreira Timóteo Simão , Achcar Jorge Alberto 
Published: August 2024

Este artigo teve como objetivo analisar a estratégia de manutenção em uma usina de açúcar e álcool localizada no estado de São Paulo, Brasil, utilizando dados de MTTR de duas linhas de processamento de cana sob a perspectiva da engenharia de confiabilidade. A pesquisa, caracterizada como um estudo de caso, empregou técnicas de modelagem estatística para analisar os tempos de reparo para todas as falhas nas moendas durante um período específico. Os tempos de reparo foram modelados utilizando uma distribuição log-normal para os dados na escala original ou uma distribuição normal para os dados transformados pelos logaritmos na base natural dos tempos de reparo. Embora os tempos médios de reparo tenham sido estatisticamente semelhantes para as duas moendas, a análise estatística revelou a influência de diversos fatores na duração dos reparos em ambas. Além disso, o estudo identificou questões cruciais para a estratégia de manutenção da empresa, destacando resultados com implicações significativas para melhorar o desempenho da área de manutenção e a confiabilidade dos equipamentos, contribuindo para a maior competitividade da empresa.

Palavras-chave: Modelos de confiabilidade, gestão da manutenção, análise estatística, tempos de manutenção, cana-de-açúcar, etanol.
Indonesia Literature in Translation (Indonesia and Japanese Translation Context)
Authors: Rosliana Lina 
Published: August 2024

Indonesia has rich literature that is not widely known outside the country's borders. Translating Indonesian literary works can be the key to experiencing its literary richness and knowing its social, cultural, or political reality. There have been many studies on translating Japanese or English literature into Indonesian, but not vice versa. This study can play a role in formulating strategies for translating Indonesian literary works into foreign languages and, at the same time, become a contribution to introduce Indonesian literature through translation studies. The research questions proposed align with the study's primary objective of issues in translation; How is the passage of Indonesian literature in translation? Literary research with qualitative approaches will be conducted in this study. The stages are divided into three steps, i.e., 1) Data collection, 2) Data analysis, and 3) Data presentation. Before independence, Japan established an institution in Indonesia whose job was to translate literary works, either in book form or published in magazines and newspapers for the Indonesian people. However, in practice, this was done to control the reading of the Indonesian people and for propaganda purposes. Thus, the literary works circulated and translated supported colonial projects. After independence, the Japanese grant program for translating Southeast Asian literary works has also significantly impacted the number of Indonesian literary works translated into Japanese. However, these translated works have yet to reach the Japanese public and are mostly accessed by a limited circle of Indonesian observers in Japan.
THE CHEMICAL TOPOLOGICAL GRAPH ASSOCIATED WITH THE NILPOTENT GRAPH OF A MODULO RING OF PRIME POWER ORDER
Authors: Malik Deny Putra , Husni Muhammad Naoval , Miftahurrahman Miftahurrahman , Wardhana I Gede Adhitya Wisnu , Semil @ Ismail Ghazali 
Published: August 2024

Chemical topological graph theory constitutes a subdomain within mathematical chemistry that leverages graph theory to model chemical molecules. In this context, a chemical graph serves as a graphical representation of molecular structures. Specifically, a chemical molecule is portrayed as a graph wherein atoms are denoted as vertices, and the interatomic bonds are represented as edges within the graph. Various molecular properties are intricately linked to the topological indices of these molecular graphs. Notably, commonly employed indices encompass the Wiener Index, the Gutman Index, and the Zagreb Index. This study is directed towards elucidating the numerical invariance and topological indices inherent to a nilpotent graph originating from a modulo integer ring with prime order. Consequently, the investigation seeks to discern how the Wiener Index, the Zagreb Index, and other characteristics of the nilpotent graph manifest within a ring of integers modulo prime order powers.
Brazil nuts potential: effects on lipid peroxidation and heart health in nephrectomized rats
Authors: Menezes Agatha Cristie , Brito Michele Lima , Almeida Patricia Pereira , Da Cruz Beatriz Oliveira , da Silva Costa Nathalia , D’Avila Pereira Aline , Castañon Cecilia , Nunes Degani Viviane Alexandre , Medeiros de França Cardozo Ludmila Ferreira , Magliano D’Angelo Carlo , Stockler-Pinto Milena Barcza 
Published: August 2024

Abstract

Objectives
To investigate the effects of a Brazil nut-enriched diet on the wall thickness and the left ventricular chamber diameter of the heart, and lipid peroxidation in a CKD-induced model.

Methods
Male Wistar rats at 12 weeks of age were divided into two groups (n=16/group): the Nx group, which underwent 5/6 nephrectomy, and the Sham group, as a control. After 5 weeks, the groups were subdivided according to diet (n=8/group): the Nx and Sham groups received a control diet; the Nx5% and Sham5% groups received a diet enriched with 5 % Brazil nuts for 8 weeks. The left ventricular thickening and chamber diameter were determined. Plasma biochemical parameters were evaluated. Analysis of thiobarbituric acid reactive substances (TBARS) and antioxidant enzyme activity was performed in the plasma and the left ventricle (LV). LV mRNA expression of nuclear factor-kappa B (NF-κB) and nuclear factor erythroid 2-related factor 2 (Nrf2) was evaluated by reverse transcription-polymerase chain reaction.

Results
The Nx5% group showed a remodeled LV wall with decreased thickness compared to the Nx group (p=0.016). Furthermore, LV TBARS concentration was reduced in the Nx5% group (p=0.0064). In addition, the Nx5% group showed an increase in plasma GPx activity (p=0.0431). No significant results were found concerning the LV mRNA expression of NF-κB and Nrf2 genes.

Conclusions
A Brazil nut-enriched diet decreased LV thickness and LV TBARS concentration and increased GPx activity in a 5/6 nephrectomy experimental model, making it a promising adjuvant therapy to improve antioxidant status and cardiovascular outcomes in chronic kidney disease.
Critique of Reification of Art and Creativity in the Digital Age: A Lukácsian Approach to AI and NFT Art
Authors: Poposki Zoran 
Published: August 2024

Abstract
This article critically examines the emergent phenomena of AI-generated and NFT art through the lens of Georg Lukács’ theory of reification and its existential implications. Lukács argued that under capitalism, social relations and human experiences are transformed into objective, quantifiable commodities, leading to a fragmented and alienated consciousness. Applying this framework to AI and NFT art, these technologies can be said to represent extreme examples of the reification of art and creativity in the digital age. AI art generators reduce artistic production to abstract, computable properties divorced from lived experience, while NFTs transform digital art into speculative commodities, imposing the logic of private property and exchange value onto the previously open domain of online culture. The existential dimension of this reification is explored, raising questions about the nature of creativity, originality, and the value of art in an increasingly financialized and automated world. The article suggests that a Lukácsian critique must not only diagnose the reified character of these cultural forms but also identify their potential for resistance and transformation, pointing toward a re-humanized and emancipatory vision of art in the digital age. Contemporary theorists such as Tiziana Terranova, Nick Dyer-Witheford, and Benjamin Noys are invoked to further elucidate these issues.
Longitudinal Analysis of Functional Capacity in Nursing Home Residents During the COVID-19 Pandemic
Authors: Moreno-Martin Pau , Minobes-Molina Eduard , Escribà-Salvans Anna , Oliveira Vinicius Rosa , Rierola-Fochs Sandra , Farrés-Godayol Pau , Gràcia-Micó Pol , de Souza Dyego Leandro Bezerra , Skelton Dawn A. , Jerez-Roig Javier 
Published: August 2024

Background and Purpose:
The COVID-19 pandemic has raised concerns about nursing home (NH) residents’ well-being, with recent studies indicating a significant increase in functional decline rate during this critical period. However, a comprehensive exploration of functional capacity trajectories in NH residents during the pandemic remains unexplored. This study aims to address this research gap by conducting an in-depth analysis of the impact of the COVID-19 pandemic on NH residents’ functional capacity.

Methods:
A 24-month multicenter prospective study involving 123 NH residents from Spain, with data collected at 6-month intervals over 5 waves, starting just before the pandemic’s onset. Functional capacity was assessed using the Modified Barthel Index, and data were analyzed employing the actuarial method, log-rank test, and Cox’s regression.

Results and Discussion:
The likelihood of maintaining functional capacity was unfavorable, with only a 19.3% chance of preservation for a 1-point decline (FD-1) in Barthel scores and a 50.5% probability for a 10-point decline (FD-10). Personal hygiene, eating, and toilet use were identified as the most affected activities of daily living. Urinary continence decline emerged as a risk factor for FD-1, while fecal continence decline was associated with FD-10. The probability of maintaining functional capacity in the initial 6 months of a pandemic was comparable to a 2-year non-pandemic follow-up. Pandemic-induced isolation strategies significantly impacted toileting and personal hygiene. Urinary decline was associated with minor functional decline (FD-1), while fecal decline correlated with major functional decline (FD-10). Notably, the number of days spent in room confinement did not significantly contribute to the observed decline.

Conclusions:
A substantial increase in the risk of FD among NH residents during the COVID-19 pandemic compared to the pre-pandemic period was found. It is crucial to implement urgent, targeted interventions that prioritize promoting physical activity and the implementation of mobility and toileting programs. These measures are pivotal for mitigating functional decline and enhancing the overall health and well-being of NH residents in a pandemic context.
Enhanced Expression of Two ISGs as Potential Biomarkers of Prognosis in HIV-Infected Immunological Non-Responders
Authors: Zhang Xin , He Lin , Zhang Ruifeng , Sun Haolan , Zhang Liguo , Jin Cong 
Published: August 2024

Objective:
No novel biomarkers are currently available for evaluating immune reconstitution among people living with HIV/AIDS (PLWH) receiving combined antiretroviral treatment (cART). The objective of this study was to analyze the expression patterns of interferon-stimulating genes (ISGs) in PLWH with the aim of identifying potential biomarkers for immune reconstitution.

Methods:
Study samples were collected from 105 PLWH, including 47 immunological non-responders (INRs) and 58 immunological responders (IRs). The expression of eight ISGs in the peripheral blood in INRs and IRs were detected by RT-qPCR. Expression differences between groups were analyzed with the Mann-Whitney U test, and a logistic regression model was developed to predict immune reconstitution.

Results:
Among eight ISGs, the expression levels of IFI27 and IFI6 were significantly higher in INRs than IRs (P=0.001 and 0.005, respectively). The model combining age, CD4+ T/CD8+ T ratio, IFI27, and IFI6 had the highest diagnostic value (AUC=0.836), with an optimal cut-off value of 0.6, sensitivity of 60.5%, and specificity of 98.1%. No significant change in the expression of IFI27 and IFI6 was observed in samples collected 3 years apart (P=0.1232 and 0.4877, respectively), and the model score negatively correlated with ΔCD4+ T cells (r=−0.2888, P=0.0465).

Conclusions:
Enhanced expression of IFI27 and IFI6 in INRs are important characteristics that may serve as biomarkers of immune reconstitution after cART. The combination of age, CD4+ T/CD8+ T ratio, IFI27, and IFI6 was highly effective in discriminating INRs.
Vibrational energy levels for sulfur dioxide isotopologues
Authors: ШАРЫБКИНА К.К. , НАУМЕНКО О.В. 
Published: August 2024

Для пяти изотопологов молекулы SO2: 32S16O2, 34S16O2, 33S16O2, 32S18O2, 32S16O18O, получены параметры эффективного колебательного гамильтониана из подгонки к имеющимся экспериментальным данным, а также с использованием основных соотношений теории изотопозамещения. Экспериментальные колебательные уровни энергии восстанавливаются с полученными параметрами с точностью не хуже 0,025 см-1 для симметричных изотопологов. Проведено сравнение найденных колебательных уровней энергии с данными вариационного расчета, при этом исправлены квантовые числа для 93 колебательных состояний. Полученные данные могут быть полезны при идентификации и моделировании инфракрасных спектров, образованных переходами на высоковозбужденные колебательные состояния изотопологов диоксида серы, а также при анализе «горячих» спектров.
For five isotopologues of the SO2molecule: 32S16O2, 34S16O2, 33S16O2, 32S18O2, 32S16O18O, parameters of the effective vibrational Hamiltonian are derived from fitting to the available experimental data and with the use of the basic relations of the isotope substitution theory. Vibrational constants obtained from the fit reproduce the experimental vibrational energy levels within 0.025 cm1for symmetric isotopologues. The found vibrational energy levels are compared with the variational calculation data, and the quantum numbers for 93 vibrational states are corrected.
Monitoring the content of carbon monoxide in the atmosphere of oil and gas producing regions of Khanty-Mansi Autonomous Okrug using satellite data MOPPIT
Authors: АЛЕКСЕЕВА М.Н. , ПУСТОВАЛОВ К.Н. , ГОЛОВАЦКАЯ Е.А. , ЯЩЕНКО И.Г. 
Published: August 2024

Представлены результаты анализа изменчивости содержания оксида углерода (СО) в атмосфере над нефтезагрязненной территорией в ХМАО по данным спутникового зондирования (Terra/MOPITT). Изучена суточная и сезонная динамика интегрального содержания и приземной концентрации CO. Среднее содержание СО (интегральное и приземное) в нефтезагрязненном районе превышает аналогичные значения в фоновом районе как в целом для теплого периода года, так и для большинства месяцев. Результаты исследования указывают на достаточную чувствительность прибора MOPPIT для определения концентрации оксида углерода в условиях антропогенной деятельности.
This work is devoted to the issues of remote monitoring of atmospheric gas concentrations using the example of carbon monoxide over the oil and gas producing territories of the Khanty-Mansi Autonomous Okrug with a high concentration of fuel combustion sources. The analysis of the variability of carbon monoxide (CO) content in the atmosphere over an oil-polluted area in the Khanty-Mansi Autonomous Okrug is performed based on satellite sensing data (Terra/MOPITT). The daily and seasonal dynamics of the integral content and surface concentration of CO are studied. The average CO content (integral and surface) in the oil-polluted area exceeds similar values in the background area, both in general for the warm period of the year and for most months. There are no significant differences in the CO content above the background and contaminated areas, which may be due to the mixing of air masses; however, the average CO content (integral and ground level) in the contaminated area exceeds similar values in the background area, which is explained by the presence of stationary CO sources in the former, including flare units.
Land Dispute Settlement: A Key Issue to Ensure Long-lasting Peace in Chattogram Hill Tracts
Authors: Siddiqui Muhammad Ali Haider 
Published: August 2024

Chattogram Hill Tracts (CHT) constitutes nearly 10% of the total landmass of Bangladesh. Extremely beautiful, yet this part of Bangladesh was ravaged by almost 27 years of insurgency. It indeed came to a formal end with the signing of the historic Peace Agreement between the Government of Bangladesh and Parbattya Chattagram Jana Sanghati Samiti (PCJSS) on 02 December 1997. So far, 48 out of the 72 clauses have already been implemented and the rest are in the process. The land issue is one of the major issues that have beset the progress of the agreement. Most communal clashes and unwanted situations usually erupt from disputes over the possession of the land. To settle the land disputes, a commission was formed in 2001 in light of the CHT agreement. The government has recently amended the Land Commission Act 2001 into 2016 as per the demand of the tribal leadership. The amendment has been viewed as discriminatory by the Bengali community, which fears losing their land rights if it is implemented. Against this backdrop, the research was undertaken to identify the probable challenges for the Land Commission to settle the land disputes and suggest a comprehensive modality to resolve the crisis. The study followed a mixed method methodology. During the study, issues like the credibility of the Commission, the land management system in CHT, communal disharmony, absence of a cadastral survey, the security situation, and conflicting issues of the amended Land Commission Act -2016, came out as the major challenges and impediments to the peaceful resolution of land disputes.The study suggests a consensual approach of the Government and concerned stakeholders to address the identified issues in order to resolve land disputes in CHT. As this also bears significant importance in the full implementation of the hard-earned CHT Agreement, any delay in the settlement of land disputes would presumably complicate the situation and likely make the overall security environment of the CHT region unstable once again.