bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hepatitis B clinical care provision in pregnancy: A whole‐of‐population linkage study in Victoria, Australia
Authors: MacLachlan Jennifer H , Romero Nicole , Allard Nicole , Rowe Stacey L , Cowie Benjamin C 
Published: August 2024

AbstractBackground and AimPregnancy is a key setting for engagement in chronic hepatitis B (CHB) care, due to the implications for transmission to the infant and antenatal diagnosis representing an opportunity for ongoing follow‐up. This study aimed to identify the coverage and predictors of clinical care for women with CHB during and after pregnancy in a population‐level cohort.MethodsNotified CHB cases in Victoria, Australia, were linked with hospitalizations, medical services, and prescribing data, covering the period 1991–2018. Women with an admission for a live birth were identified and services provided during pregnancy were assessed, including general practitioner (GP) or specialist visits, viral load and serology testing, and antiviral treatment. Viral load and serology testing coverage ware also assessed for the 2‐year period following pregnancy. Demographic and clinical predictors of viral load testing during pregnancy were assessed.ResultsA total of 11 015 birth events occurred for 6090 women with CHB. During pregnancy most had a GP consultation (91.6%); however, only 39.5% had viral load testing and 41.4% had a gastroenterology or infectious diseases specialist consultation. Viral load testing and serology testing in the 2 years after pregnancy occurred in approximately half (47.9% and 52.2%, respectively) with increases over time. Viral load testing was more likely in those born overseas, those with more than one previous birth, and those living in Melbourne.ConclusionsDespite improvements over time, key gaps were identified in the provision of CHB clinical care during and after pregnancy, with implications for ongoing transmission and adverse outcomes.
Progesterone may be a regulator and B12 could be an indicator of the proximal D4Z4 repeat methylation status on 4q35ter
Authors: Hangul Ceren , Ozcan Filiz , Darbas Sule , Uysal Hilmi , Koc Ayse Filiz , Berker Karauzum Sibel 
Published: August 2024

AbstractFacioscapulohumeral dystrophy (FSHD) has a hypomethylation‐related epigenetic background and exhibits a different course in male and female patients. The differences between males and females have been linked to the levels of sex hormones. This study is the first to investigate the possible effect of these hormones on methylation status. We hypothesized that the levels of sex‐related hormones, estradiol, testosterone, progesterone, and prolactin might be associated with the methylation status of the proximal part of the D4Z4. We also investigated the effect of fT3, folic acid, and vitamin B12 levels. We collected blood from 28 FSHD patients and 28 controls. DNA was extracted from each individual for bisulfite methylation analysis and serum was separated for biochemical analysis of estradiol, testosterone, progesterone, prolactin, fT3, folic acid, and B12 analysis. Methylation analysis was specified to the DR1, 5P regions and the proximal region covering both DR1 and 5P. Methylation levels were compared between FSHD patients and controls. The correlation of methylation levels with estradiol, testosterone, progesterone, prolactin, fT3, folic acid, and B12 was investigated. We found that the 5P region and the proximal region were significantly hypomethylated in FSHD patients compared to the controls, but not the DR1 region. Male patients exhibited a significant reduction in DNA methylation compared to male controls. Older FSHD patients exhibited a notable decrease in fT3 levels and hypomethylation of the 5P region. Analyses of each CpG revealed seven hypomethylated positions that were significantly different from the control group. Two of the positions demonstrated a correlation with progesterone in the control group. With the exception of one position, the methylation levels were inversely correlated with vitamin B12 in FSHD patients. The results of our study indicate that the methylation of the proximal D4Z4 region, particularly at specific positions, may be associated with progesterone. In addition, vitamin B12 may be an indicator of hypomethylation. We suggest that examining position‐specific methylations may be a useful approach for the development of epigenetic treatment modalities.image
Your coworkers can make you sick: An investigation of coworker undermining and employee health
Authors: Costa Sandra , Velez Maria João , López Aníbal 
Published: August 2024

AbstractAlthough mistreatment in the workplace has been widely acknowledged, the impact of coworker undermining has not been adequately explored in the literature. Using insights from the job demands–resources model, we suggest that coworker undermining is a job demand that is associated with negative affect and somatic complaints. In mitigation of this, we propose two personal resources (i.e. forgiveness and revenge cognitions) as buffers of the positive relationship between coworker undermining and somatic complaints via negative affect. We explore these relationships in a time‐lagged study involving 229 participants who responded to three surveys over a month‐long period. Our findings show that coworker undermining is related to high levels of negative affect in the following week, and that this spills over to somatic complaints. However, this is only true for victims of undermining who do not forgive their colleagues.
Evidence, Policy, Education, and Neuroscience—The State of Play in the UK
Authors: Thomas Michael S. C. , Howard‐Jones Paul , Dudman‐Jones Jeremy , Palmer Lucy R. J. , Bowen Astrid E. J. , Perry Roisin C. 
Published: August 2024

AbstractIn this article, we give an overview of translational educational neuroscience (mind, brain, and education) in the United Kingdom. We consider the state of translation, describing respectively the state of the dialogue between researchers and educators, the state of evaluation of approaches to improve educational outcomes, and the state of innovation in research translation. We consider the teacher perspective. What do UK teachers think about educational neuroscience and its potential for informing classroom practice, and how do ideas about pedagogical approaches feature among their everyday concerns? We describe the results of a recent survey from a representative sample of over 1,000 UK teachers, and a case study of a UK high school teacher who employs educational neuroscience in his practice and what this entails. Lastly, we consider the policy perspective and assess the recent move by the UK government to introduce knowledge of cognitive science into initial and early‐career teacher training.
Randomized double‐blind placebo‐controlled study to evaluate the effect of long‐acting mesalamine on postinfectious irritable bowel syndrome with diarrhea
Authors: Tuteja Ashok K. , Leung Daniel T. , Fang John C. , Talley Nicholas. J. , Stoddard Gregory J. 
Published: August 2024

AbstractBackgroundA subset of patients with irritable bowel syndrome (IBS) develop their symptoms after gastroenteritis, referred to as postinfectious IBS (PI‐IBS). PI‐IBS is associated with low‐grade intestinal inflammation. Previous studies have evaluated mesalamine, an anti‐inflammatory drug, in patients with IBS. We evaluated the efficacy of long‐acting mesalamine in patients with PI‐IBS.MethodsSixty‐one patients who developed diarrhea‐predominant IBS (IBS‐D) after gastroenteritis were randomized to receive either 2.4 g of long‐acting mesalamine or placebo daily for 8‐weeks. The symptoms assessed were abdominal pain, bloating, stool frequency, stool consistency, severity of diarrhea and constipation, satisfaction with bowel habits, and IBS affecting or interfering with life. Quality‐of‐life (QOL) was assessed using the IBS‐QOL questionnaire. The prespecified primary outcome variable was the overall bowel symptom score (BSS) after 8‐weeks of treatment. Effect sizes were expressed as standardized mean differences (Cohen's d).ResultsFifty‐four patients completed the 8‐week treatment (n = 28 mesalamine, n = 26 placebo), 49 (91%) were male, and age range 23–71 years (mean ± SD 43 ± 13). Mesalamine demonstrated superior efficacy compared to placebo on the primary outcome variable, overall BSS (Cohen's d = 0.57, p = 0.042). Mesalamine was also superior for the secondary outcome of how much IBS affects your life in general (d = 0.72, p = 0.01). For the secondary outcomes of IBS symptoms, 7 of the 7 symptoms had trends of mesalamine superiority. For the secondary outcomes of IBS‐QOL subscales, 8 of 9 had trends of mesalamine superiority.ConclusionIn patients with PI‐IBS, long‐acting mesalamine demonstrated to be effective in reducing IBS symptoms and improving QOL.
Use of telehealth simulation to teach the enhanced primary care RN role through community/public health‐focused simulations
Authors: Sawin Erika Metzler , Hummel Rebecca , Lam Christina , Mullen Lauren , Switzer Tina , Robinson Jamie , Walton Brandi 
Published: August 2024

AbstractAmerica is facing a primary care provider shortage. Enhanced primary care RNs (EPC‐RNs), registered nurses working at the top of their practice scope, can be an important part of community‐based primary care provision. Typically, community health nursing education has not included primary care‐based clinical experiences, and there is a clinical site shortage. Teaching students about EPC‐RN roles can be an important domain of community/public health nursing education. Simulation is a creative pedagogical approach to learning about the EPC‐RN role. The purpose of this manuscript is to 1) describe EPC‐RN Telehealth Simulation development; and 2) describe student simulation feedback.Nursing faculty and simulation experts designed five simulations for community health students to teach about the EPC‐RN role, incorporating recommendations from the Quad Council Coalition of Public Health Nursing Organizations community/public health nursing competencies and the National Competencies for Registered Nurses in Primary Care.Retrospective, descriptive quantitative, and qualitative student feedback data (n = 519) was collected through QuestionPro over multiple semesters. Student feedback data demonstrated support of the use of the simulations in community/public health nursing education.The EPC‐RN Telehealth Simulations prepared pre‐licensure nursing students to practice in community‐based primary care settings. Innovative, sustainable experiences such as this can improve community/public health nursing education.
Antifungal activity of Bacillus velezensis and Pseudomonas azotoformans isolated from compost tea against anthracnose (Colletotrichum spp.) on strawberry fruit
Authors: Popescu Irina , Loganathan A. Kiripuvaney , Graham Hailey R. , Avis Tyler J. 
Published: August 2024

AbstractAnthracnose, caused by Colletotrichum spp., is a threat to strawberry production globally. Unlike their chemical counterparts, microbial biofungicides offer a method of postharvest fungal disease control that is safe, sustainable and less affected by pathogen resistance. The present study evaluated the antifungal effects of three bacteria, Bacillus velezensis strains SH1 and SH2 and Pseudomonas azotoformans strain SH3, obtained from sheep manure compost tea. The bacteria or their cell‐free filtrates were tested against Colletotrichum acutatum and Colletotrichum gloeosporioides in bioassays and against strawberry anthracnose. In addition, precipitated or extracted extracellular fractions were tested to determine the effects on membrane permeability of Colletotrichum spp. spores. Confrontation assay results showed all bacteria inhibited mycelial growth, with B. velezensis SH1 and P. azotoformans SH3 being the most effective. All cell‐free filtrates inhibited mycelial growth with B. velezensis SH1 and SH2 resulting in the highest inhibition. The bacteria suppressed anthracnose lesions on strawberry fruit although effective treatments varied by causal mould. B. velezensis SH1 and SH2 significantly permeabilized spore membranes, indicating antibiosis as a possible mode of action. Investigation into antimicrobial compound production found various homologues of the lipopeptides fengycin, iturin and surfactin were produced by B. velezensis SH1 and SH2. Results suggest that lipopeptides produced by B. velezensis strains permeabilize Colletotrichum cell membranes, and that fengycins were the most inhibitory of the lipopeptides against Colletotrichum spp.
Can world heritage sites boost sales in non‐tourism firms? The role of visibility
Authors: Liu Yiming , Cheng Hua 
Published: August 2024

AbstractWorld Heritage sites can positively impact local manufacturing industries. Using two‐way fixed effects estimation, we find that manufacturing firms in cities with World Heritage sites see a 9% increase in operating revenue. This finding is robust to matching methods and a control function method. The impact is especially strong for businesses with low online visibility, highlighting that World Heritage sites enhance visibility toward lesser‐known enterprises. The study also shows that the positive impact on sales is greater in cities with better support for economic development, consistent with the notion that firms need good industrial infrastructure and financial resources to produce high‐quality goods.
Somatosensory processing in long COVID fatigue and its relations with physiological and psychological factors
Authors: Thomas Bethan , Pattinson Rachael , Bundy Christine , Davies Jennifer L. 
Published: August 2024

AbstractFatigue is prevalent amongst people with long COVID, but is poorly understood. The sensory attenuation framework proposes that impairments in sensory processing lead to heightened perception of effort, driving fatigue. This study aims to investigate the role of somatosensory processing impairments in long COVID fatigue and quantify how sensory processing relates to other prominent symptoms of long COVID including autonomic dysfunction, mood and illness beliefs in driving the experience of fatigue. We will recruit 44 individuals with long COVID fatigue and 44 individuals with neither long COVID nor fatigue (controls). Our primary objective is to compare baseline somatosensory processing between individuals with long COVID fatigue and controls. Additionally, we will explore the associations between somatosensory processing, fatigability and the level of fatigue induced by cognitive and physical exertion. Due to the complex nature of fatigue, we will also investigate how long COVID, state fatigue, perceived effort, mood, illness beliefs, autonomic symptoms and autonomic nervous system function interact to predict trait fatigue. This comprehensive investigation aims to elucidate how sensory processing and other prominent symptoms interact to impact the experience of fatigue.
Modeling and Experimental Validation of Prechamber Jet Penetration Considering Jet Density and Ejection Pressure Variations
Authors: Wu Shen , Moriyoshi Yasuo , Li Tie , Zhou Xinyi , Kuboyama Tatsuya , Chen Run , Morikawa Koji , Kimura Shin , Huang Shuai , Tanoue Kimitoshi 
Published: August 2024

Abstract
Although prechamber (PC) is regarded as a promising solution to enhance ignition in lean-burn gas engines, a lack of comprehensive understanding of PC jet penetration dynamics remains. This study proposed a zero-dimensional (0D) model for PC jet penetration, considering the mixing of combustion products and unburned gases in jets and the floating ejection pressure. A combustion completion degree was defined by employing fuel properties and heat release to estimate the time-varying jet density. Pressure differences between the PC and the main chamber (MC) were referred to as the ejection pressure. Then, this model was validated against experimental data from a constant volume chamber (CVC) and a rapid compression and expansion machine (RCEM) with CH4-H2 blends at different equivalent ratios. Results showed that the proposed model can provide a good prediction in stationary and turbulent fields with the calibrated model coefficient. The overall jet penetration exhibits a t0.5 dependence due to its single-phase characteristic and the relatively lower density compared to the ambient gas in MC. The flame propagation speed and heat release in PC influence the combustion completion degree at the start of jet ejection. The mass fraction of burned gas in the ejected jet grows in response to the mixture equivalent ratio. Jet penetration is primarily driven by ejection pressure, with tip dynamics barely affected by the pressure difference after peaks. Tip penetration intensity rises with increasing fuel equivalent ratio and H2 addition, owing to the faster flame propagation. These findings can offer useful suggestions for model-based design and combustion model development for gas engines.
Damage to a High Bypass Ratio Fan During Uncrewed Aircraft Systems Ingestions
Authors: D'Souza Kiran , Sirivolu Dushyanth , Gomez Luis , Olivares Gerardo 
Published: August 2024

Abstract
Foreign object ingestion into engines has been studied for many years, but the focus has been on soft bodies (i.e., birds, ice). Recently, there has been a dramatic increase of uncrewed aircraft systems (UAS) in the airspace that represent a new threat to aircraft engines due to key components like the motor, battery, and camera being composed of hard components. Due to the differences between hard bodies and soft bodies, studies are required to understand the new threat these UAS pose to aircraft. The objective of this study is to investigate the impact of various factors such as impact orientation, fan rotational speed, relative translational speed, and radial impact location on the damage caused to a representative fan assembly. This study aims to analyze the sensitivity of these factors and their influence on the overall damage to the fan. The ingestion simulations will use a representative fan assembly model and a UAS model that has been experimentally validated at the conditions of an ingestion. This work will identify critical parameters of the ingestion and then utilize them to anticipate the extent of damage that may arise during specific stages of a flight where an ingestion is most probable. Moreover, it also compares these cases with some known baseline cases, such as a fan blade out (FBO) and bird ingestion of similar mass, to understand the likely severity compared to more studied common cases.
The Cambrian collision of the Yangtze Block with Gondwana: Evidence from provenance analyses
Authors: Han Yuyue , Ran Bo , Santosh M. , Liu Shugen , Li Zhiwu , Ye Yuehao , Lv Fan , Wang Han , Li Chao 
Published: August 2024

Abstract
The Neoproterozoic to Paleozoic Proto-Tethys Ocean has preserved critical records of Earth’s evolutionary history. The Lower Cambrian detrital strata along the northern margin of the Yangtze Block provide valuable information for gaining insight into the evolution of the Proto-Tethys Ocean, which is important in understanding the collision between the Yangtze Block and the Gondwana assembly. Here, we present comprehensive U-Pb ages and trace elements of zircons from Lower Cambrian detrital strata in the Yangtze Block. Our results revealed prominent age peaks at 600–500 Ma and 1100–800 Ma for detrital zircons in the Cambrian strata. The trace element characteristics of the detrital zircon indicate that the source rocks were mainly intermediate-felsic magmatic suites with minor input from mafic sources. These results suggest that the detrital materials were not only supplied from the interior of the Yangtze Block but also from magmatic sources in the internal orogenic belt of Gondwana.
Furthermore, the kernel density estimate plots of detrital zircon U-Pb ages indicate a stable source-sink system in the Yangtze Block during the Early Cambrian. However, our data indicate that the crustal thickness of the Yangtze Block increased significantly since ca. 526 Ma, and the cumulative characteristics of the detrital zircons indicate that the rocks were deposited in a compressional tectonic environment after ca. 526 Ma, in contrast to those during the late Neoproterozoic, which were generally deposited in an extensional tectonic environment. This transition indicates that the initial collision between the Yangtze Block and the Gondwana supercontinent might have occurred at ca. 526 Ma, marking the rapid aggregation of the northern domain of the Gondwana assembly and potentially serving as an important indicator of the closure of the Yangtze-associated Proto-Tethys Ocean. Our findings provide key insights into late Neoproterozoic–early Paleozoic ocean-land evolution.
Impacts of the High-Pressure Bratsk Hydroelectric Power Station on Fish Population of the Bratsk Reservoir
Authors: Gerasimov Yu. V. , Pavlov D. D. , Strelnikova A. P. , Shlyapkin I. V. , Borisenko E. S. 
Published: August 2024

AbstractEnvironmental and ecological effects of the dam of the high-pressure Bratsk Hydroelectric Power Station (HPS) on the fish population and the probability of fish downstream migration from the Bratsk Reservoir have been studied. It has been revealed that thermal stratification of the water column is a significant factor in the ecological differentiation of the fish population in the upper reaches of high-pressure hydroelectric plants. According to hydroacoustics data, most of the ichthyomass, consisting of “warm-water” representatives of the Percidae (65%) and Cyprinidae (22%) families, is concentrated in the relatively warm layer of the epilimnion. Juvenile fish from 30 to 50 mm in size (up to 70% of the total fish number in this layer) are also concentrated here. In the cold-water hypolimnion, the fish population is represented by large single individuals of whitefish (Coregoninae). The data on distribution of fish in the lower and upper reaches of the dam, fish nutrition patterns, growth rate, and the presence of injuries that occur when fish pass downstream through hydroelectric plant dams are presented. Revealed differences in the growth rate of perches from the upper and lower reaches are associated with their constant inhabiting of water masses with contrasting temperatures. Net catches in the lower reaches over the four seasons of research lack injured individuals. These facts prove the absence of mass downstream passage of fish through the Bratsk HPS dam. Juveniles of cyprinids and perches accumulate in the upper warm layer of 0–10 m, i.e. outside the zone of the intake flow formation, which makes their entrance to intake openings at a depth of more than 20 m hardly possible.
X-Ray- and Synchrotron-Radiation Study of the Defect Structure of Epitaxial ZnO Films Grown by Magnetron Deposition on Al2O3 and LaMgAl11O19 Substrates with (0001) Orientation
Authors: Zhernova V. A. , Volkovsky Yu. A. , Folomeshkin M. S. , Seregin A. Yu. , Prosekov P. A. , Muslimov A. E. , Butashin A. V. , Ismailov A. M. , Grigoriev Yu. V. , Pisarevsky Yu. V. , Kanevsky V. M. , Blagov A. E. , Kovalchuk M. V. 
Published: August 2024

Abstract
The results of studying the structural features of samples of zinc-oxide films obtained by magnetron deposition on chips of lanthanum-magnesium hexaaluminate and the surface of sapphire substrates with a gold buffer layer are presented. Analysis of the structure and morphology of the films is carried out using a set of methods, including high-resolution X-ray diffractometry, the method of constructing pole figures, and transmission electron microscopy. It is shown that when using cleavages of lanthanum-magnesium hexaaluminate, an epitaxial ZnO film is formed without signs of growth rotating domains. The use of a gold buffer layer during growth on sapphire substrates improves the crystalline quality of ZnO films, but does not completely suppress domain growth.