bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Tonic to the Empire?: The 1951 Festival of Britain and the Empire-Commonwealth
Authors: Heinonen Alayna 
Published: March 2015

A unique feat of an economically and physically ravaged post-war Britain, the 1951 Festival of Britain produced an ‘autobiography of a nation’ intended to instill a nationalistic sense of recovery after total war. Centrally located on the South Bank, the Festival hosted a series of exhibitions celebrating British achievements in the fields of industry, science, technology, architecture, and the arts. With few exceptions, the vast majority of scholarship assesses the Festival through its national framework, and as an attempt to facilitate post-war economic recovery under the Labour government. This article re-examines the imperial concerns underlying the Festival amidst profound global changes in the post-war era. The ‘centrifugal’ development of the inter- and post-war Commonwealth fatally compromised administrative efforts to cultivate a tonic to the Empire through Festival exhibits. Former colonies and Dominions, emboldened by their independence from the metropole, refused to partake in an event that idealised a modernity that rested only in Britain. Representatives from India, Pakistan, and Ceylon, as new Commonwealth members, dissented against indications of their inferior status. These complications during the Festival's organisation expose the fractures in the transition from an exclusive, British-led Commonwealth to a multiracial Commonwealth.
Scenarii pour (quasi-) fin du monde. Traiter les dangers au CERN
Authors: Houdart Sophie 
Published: March 2015

Au large de Genève court le plus grand dispositif expérimental jamais construit, le LHC, conçu pour comprendre comment s’est aggloméré l’univers. Les physiciens des particules, à l’échelle internationale, y expérimentent les théories physiques les plus avancées sur l’origine et le devenir du monde. Lové 100 mètres sous terre, et donc invisible dans le paysage, cette machine extraordinaire est, en surface, le point de mire de multiples attentions et l’objet de mesures incessantes. Ce dont elle traite (le Big Bang, les trous noirs, l’antimatière…), son envergure, son empreinte territoriale sont propres à nourrir des scénarios catastrophe que le CERN doit scrupuleusement désamorcer à mesure qu’ils surgissent en usant de procédés hétérogènes : mesures techniques, normes juridiques, monitoring de l’environnement.
Mesurer l'air. Une fuite de phosgène à l'usine toulousaine Tolochimie en 1973
Authors: Charvolin Florian 
Published: March 2015

Le 19 septembre 1973, un gaz très toxique est rejeté dans l’atmosphère à l’usine Tolochimie de Toulouse. L’analyse des archives permet de revenir sur ce type d’incident, qui interroge les manières de mesurer et de traiter l’air ambiant dans un milieu industriel. Dans l’usine, la traduction de l’incident porte sur le confinement paramétrable des gaz ; dans la ville, on parle de nuage à la mesure imprécise, au danger potentiellement débordant qu’il va falloir résorber : deux manières de contenir l’air, et qui révèlent un cas exemplaire de pollution.
La quête identitaire des Caldoches en Nouvelle-Calédonie
Authors: Carteron Benoît 
Published: March 2015

Comment les Caldoches, dans leur appartenance subjective, s’approprient-ils les catégories d’identification et diverses images du groupe ? Comment gèrent-ils les tensions qu’elles révèlent ou suscitent ? L’article analyse ces appartenances multiples, l’opposition aux Métropolitains et les proximités avec le monde kanak comme autant de processus d’auto-identifications pris entre affirmation singulière et construction d’un pays commun.
André Varagnac et les contraintes de l'histoire. La trajectoire tourmentée d'un folkloriste après guerre
Authors: Chandivert Arnauld 
Published: March 2015

Cet article examine la seconde partie de la carrière, après 1945, d’un folkloriste et ethnologue de la France récemment « redécouvert », André Varagnac (1894-1983). A partir de la consultation de ses archives personnelles, il s’agit de relier ses pratiques et positions scientifiques aux « univers des possibles » qui s’ouvraient à lui après la guerre, dans une période de redéfinition de l’ethnologie de la France. Ce n’est pas une lecture purement chronologique de la trajectoire de ce chercheur qui a été retenue, l’objectif étant de montrer combien, en ce cas, historiographie disciplinaire, carrière scientifique et contextes historiques s’entremêlent, pour permettre de comprendre les modalités d’une reconstruction de l’ethnologie de la France après-guerre qui s’opéra sans lui.
Formes sous influences
Authors: Perpère Antoine 
Published: March 2015

L’artiste-expérimentateur de drogue retranscrit ou tente de retranscrire grâce aux moyens plastiques dont il dispose ou qu’il invente un « autre lieu » visité, ouvert par l’action d’un psychotrope. On pourrait distinguer trois tactiques de création, caractérisable par trois mots : Traduire / Simuler / Représenter.
DAP12-Based Activating Chimeric Antigen Receptor for NK Cell Tumor Immunotherapy
Authors: Töpfer Katrin , Cartellieri Marc , Michen Susanne , Wiedemuth Ralf , Müller Nadja , Lindemann Dirk , Bachmann Michael , Füssel Monika , Schackert Gabriele , Temme Achim 
Published: March 2015

Abstract
NK cells are emerging as new effectors for immunotherapy of cancer. In particular, the genetic engraftment of chimeric Ag receptors (CARs) in NK cells is a promising strategy to redirect NK cells to otherwise NK cell–resistant tumor cells. On the basis of DNAX-activation protein 12 (DAP12), a signaling adaptor molecule involved in signal transduction of activating NK cell receptors, we generated a new type of CAR targeting the prostate stem cell Ag (PSCA). We demonstrate in this article that this CAR, designated anti–PSCA-DAP12, consisting of DAP12 fused to the anti-PSCA single-chain Ab fragment scFv(AM1) confers improved cytotoxicity to the NK cell line YTS against PSCA-positive tumor cells when compared with a CAR containing the CD3ζ signaling chain. Further analyses revealed phosphorylation of the DAP12-associated ZAP-70 kinase and IFN-γ release of CAR-engineered cells after contact with PSCA-positive target cells. YTS cells modified with DAP12 alone or with a CAR bearing a phosphorylation-defective ITAM were not activated. Notably, infused YTS cells armed with anti–PSCA-DAP12 caused delayed tumor xenograft growth and resulted in complete tumor eradication in a significant fraction of treated mice. The feasibility of the DAP12-based CAR was further tested in human primary NK cells and confers specific cytotoxicity against KIR/HLA-matched PSCA-positive tumor cells, which was further enhanced by KIR-HLA mismatches. We conclude that NK cells engineered with DAP12-based CARs are a promising tool for adoptive tumor immunotherapy.
B Cell Rab7 Mediates Induction of Activation-Induced Cytidine Deaminase Expression and Class-Switching in T-Dependent and T-Independent Antibody Responses
Authors: Pone Egest J. , Lam Tonika , Lou Zheng , Wang Rui , Chen Yuhui , Liu Dongfang , Edinger Aimee L. , Xu Zhenming , Casali Paolo 
Published: March 2015

Abstract
Class switch DNA recombination (CSR) is central to the maturation of the Ab response because it diversifies Ab effector functions. Like somatic hypermutation, CSR requires activation-induced cytidine deaminase (AID), whose expression is restricted to B cells, as induced by CD40 engagement or dual TLR-BCR engagement (primary CSR-inducing stimuli). By constructing conditional knockout Igh+/Cγ1-creRab7fl/fl mice, we identified a B cell–intrinsic role for Rab7, a small GTPase involved in intracellular membrane functions, in mediating AID induction and CSR. Igh+/Cγ1-creRab7fl/fl mice displayed normal B and T cell development and were deficient in Rab7 only in B cells undergoing IghCγ1-cre Iγ1-Sγ1-Cγ1-cre transcription, as induced—like Igh germline Iγ1-Sγ1-Cγ1 and Iε-Sε-Cε transcription—by IL-4 in conjunction with a primary CSR-inducing stimulus. These mice could not mount T-independent or T-dependent class-switched IgG1 or IgE responses while maintaining normal IgM levels. Igh+/Cγ1-creRab7fl/fl B cells showed, in vivo and in vitro, normal proliferation and survival, normal Blimp-1 expression and plasma cell differentiation, as well as intact activation of the noncanonical NF-κB, p38 kinase, and ERK1/2 kinase pathways. They, however, were defective in AID expression and CSR in vivo and in vitro, as induced by CD40 engagement or dual TLR1/2-, TLR4-, TLR7-, or TLR9-BCR engagement. In Igh+/Cγ1-creRab7fl/fl B cells, CSR was rescued by enforced AID expression. These findings, together with our demonstration that Rab7-mediated canonical NF-κB activation, as critical to AID induction, outline a novel role of Rab7 in signaling pathways that lead to AID expression and CSR, likely by promoting assembly of signaling complexes along intracellular membranes.
Managing diabetes during Navratris with special focus on Durga pujas
Authors: Dutta Deep , Biswas Krishna , Sharma Meha , Maskey Robin , Baruah Manash , Amin Mohammod 
Published: March 2015

AbstractFasting during festivals is a common practice across all religions, believed to be associated with spiritual well-being. No literature is available addressing the challenges associated with blood glucose control in patients with diabetes during the festivals of Navratri and Durga puja, which are associated with both culinary extravagances and ritualistic fasting. Fasting alternating with binge eating can result in severe metabolic alterations, increasing both morbidity and mortality in diabetes. Dietary restraint is central to ensuring adequate glycemic control during Navratris and Durga pujas. Ritualistic fasting and dietary changes should be avoided in patients with poorly controlled diabetes with multiple comorbidities. Sulfonylureas should be avoided in case of prolonged fasting. Fast should be broken whenever blood glucose is < 70mg/dl. Target blood glucose during fasting state is 100-200mg/dl. Increasing awareness among patients, highlighting the need to enjoy festivals responsibly, and promoting healthy diet habits and exercise have an important role in maintaining glycemic control during Navratri and Durga pujas.
Magnetic resonance imaging of the temporomandibular joint acquired using different parameters
Authors: Alonso M. , Gamba T. , Lopes S. , Cruz A. , Freitas D. , Haiter-Neto F. 
Published: March 2015

Abstract
Introduction: Magnetic resonance imaging (MRI) is considered the examination of choice for the diagnosis of abnormalities in the TMJ. Considering the difficulty in defining and standardizing the diagnostic criteria, and the need for more accurate and reliable diagnosis of conditions in the TMJ, the aim of the present study was to compare three different MRI parameters: Tl-weighted, T2-weighted and proton density-weighted in the diagnosis of changes in the temporomandibular joint. Materials and Methods: Fifty magnetic resonance imaging examinations of the temporomandibular joint (100 temporomandibular joints) were conducted according to a protocol that evaluates disc position, disc function and bone abnormalities. The images were obtained bilaterally in parasagittal sections in closed and open mouth positions in the three studied parameters Three trained oral radiologists assessed all the images. Reliability of the intra- and inter-examiner response was analyzed using the concordance test (Fleiss' kappa; α = 0.05). Results: The reliability of the response patterns between observers for different protocols varied from very good to good. Observers were less constant in their response patterns when assessing proton density-weighted images. There was very good agreement for disc morphology, cortical bone and bone structures/functions; however, there was wide variation for medullary bone marrow signs. Conclusion: T2-weighted imaging was found to be the best examination to assess the medullary bone. For evaluating of disc morphology, cortical bone and bone structures/functions, any protocol is indicated once the protocol does not interfere with the analysis.
Sucralose induced pancreatic toxicity in albino rats: Histomorphological evidence
Authors: Gupta S. , Kalra S. , Bharihoke V. , Dhurandhar D. 
Published: March 2015

AbstractIn the present world people have become conscious of the fact that sugar is one of the commonest culprits for gain in weight and blood sugar in diabetes. One of the artificial sweetener, sucralose is widely used by diabetics is still under strict scrutiny because of the contradictory feedbacks obtained from various studies, often discouraging its use. Therefore, there arises a need to check whether the use of sucralose is safe or not. The present study was designed to determine to evaluate and compare the histological changes of sucralose on the islets of pancreas in albino rats. Methods: The adult Wistar albino rats were given sucralose orally by gavage in the dose of 3gms/kg body weight/day dissolved in distilled water and only distilled water for 30 days to experimental and control groups respectively. The animals were weighed prior to and after the experiment. The animals were sacrificed on day 31. The pancreas was dissected and observed grossly. Tissue was processed; paraffin blocks were prepared and 8 micron thick sections were cut. Sections were stained with Haemotoxylin and Eosin and Gomori's stains. Results: Pancreatic toxicity was observed in the form of vaculation of islets, lymphocytic infilterate, degeneration of islets and acini of Pancreas. The commonly used non-lethal dose of sucralose induced damage to Pancreas is startling. Conclusion: The results obtained have wide implications for nutrient sensing and nutrition in the treatment of obesity and diabetes.
¿Qué enseñar en la educación obligatoria acerca de la alimentación y la actividad física? Un estudio con expertos
Authors: Pérez de Eulate González Lourdes , Llorente Cámara Enrique , Gavidia Valentín , Caurín Carlos , Martínez Mª José 
Published: March 2015

Este trabajo pretende identificar los problemas más relevantes para la educación obligatoria en el campo de la alimentación y la actividad física desde el punto de vista de la educación para la salud. Para ello, se realizó una revisión bibliográfica y una consulta a expertos a través de un estudio Delphi y de un encuentro presencial. Esta combinación ha permitido consensuar entre diferentes sectores profesionales no solamente una lista de problemas y contenidos competenciales necesarios sino también aquéllos considerados como prescindibles. Los resultados de este estudio permitirán actualizar la educación alimentaria en la escuela y replantearse el curriculum desde una perspectiva que integre la enseñanza de ambas áreas desde la promoción de la salud.
Le marketing de la collecte de legs. De la légitimité à proposer l’immortalité à la gestion relationnelle
Authors: Rieunier Sophie , Michel Géraldine 
Published: March 2015

Associations de solidarité, établissements d’enseignement supérieurs et institutions culturelles ont de plus en plus de besoins financiers et de moins en moins de subventions publiques. La collecte de fonds devient alors fondamentale pour leur survie. Cet article a pour objectif d’identifier les leviers de la collecte de legs à travers une étude qualitative réalisée auprès de 21 professionnels de la collecte. Les résultats montrent le rôle déterminant de la légitimité à « offrir l’immortalité » et l’importance de la relation nouée entre l’organisation et le testateur potentiel. Enfin, les implications organisationnelles et éthiques de la collecte de legs sont identifiées.
Recent Advances in the Transition‐Metal‐Catalyzed Enantioselective Synthesis of Silicon‐Stereogenic Organosilanes
Authors: Shintani Ryo 
Published: March 2015

AbstractAsymmetric catalysis is one of the most attractive and efficient ways of synthesizing chiral enantioenriched compounds from achiral precursors. Compared with the well‐investigated enantioselective preparation of carbon‐stereogenic compounds, the corresponding preparation of silicon‐stereogenic compounds is much less established. In particular, the available methods typically rely on the use of stoichiometric amounts of chiral reagents, and little progress has been made on catalytic enantioselective synthesis using prochiral organosilanes until recently. This Focus Review highlights recent advances in the catalytic enantioselective preparation of silicon‐stereogenic organosilanes under transition‐metal catalysis through desymmetrization of prochiral organosilanes including diorganodihydrosilanes and tetraorganosilanes.
Selective Aptamer‐Based Control of Intraneuronal Signaling
Authors: Lennarz Sabine , Alich Therese Christine , Kelly Tony , Blind Michael , Beck Heinz , Mayer Günter 
Published: March 2015

AbstractCellular behavior is orchestrated by the complex interactions of a myriad of intracellular signal transduction pathways. To understand and investigate the role of individual components in such signaling networks, the availability of specific inhibitors is of paramount importance. We report the generation and validation of a novel variant of an RNA aptamer that selectively inhibits the mitogen‐activated kinase pathway in neurons. We demonstrate that the aptamer retains function under intracellular conditions and that application of the aptamer through the patch‐clamp pipette efficiently inhibits mitogen‐activated kinase‐dependent synaptic plasticity. This approach introduces synthetic aptamers as generic tools, readily applicable to inhibit different components of intraneuronal signaling networks with utmost specificity.
Photothermally Reprogrammable Buckling of Nanocomposite Gel Sheets
Authors: Hauser Adam W. , Evans Arthur A. , Na Jun‐Hee , Hayward Ryan C. 
Published: March 2015

AbstractPatterning deformation within the plane of thin elastic sheets represents a powerful tool for the definition of complex and stimuli‐responsive 3D buckled shapes. Previous experimental methods, however, have focused on sheets that access a limited number of shapes pre‐programmed into the sheet, restricting the degree of dynamic control. Here, we demonstrate on‐demand reconfigurable buckling of poly(N‐isopropylacrylamide‐co‐acrylic acid) (PNIPAM) hydrogel network films containing gold nanoparticles (AuNPs) by patterned photothermal deswelling. Predictable, easily controllable, and reversible transformations from a single flat gel sheet to numerous different three‐dimensional forms are shown. Importantly, the response time is limited by poroelastic mass transport, rather than photochemical switching kinetics, enabling reconfiguration of shape on timescales of several seconds, with further increases in speed possible by reducing film thickness.
Velocity Regulation in Pmsms Using Standard Field Oriented Control Plus Adaptation
Authors: Mendoza‐Mondragón F. , Hernández‐Guzmán V.M. , Carrillo‐Serrano R.V. 
Published: March 2015

AbstractIn this paper we present a control scheme for permanent magnet synchronous motors which is proven to be stable and globally convergent to the constant desired velocity. Our controller only differs from standard field oriented control by some simple adaptive terms and performance achieved by both controllers is almost identical. Thus, the main contribution of the present paper is to introduce a formal stability proof which is the closest, to date, to explaining why standard field oriented control of permanent magnet synchronous motors works well in practice providing explicit tuning guidelines. We stress that a global stability proof for standard field oriented control of permanent magnet synchronous motors has not existed until now, which makes the importance of our contribution remarkable.
ChemInform Abstract: Chemical Bonding in RFe6Ge4 (R: Li, Sc, Zr) and LuTi6Sn4 with Rhombohedral LiFe6Ge4 Type Structure.
Authors: Matar Samir F. , Fickenscher Thomas , Gerke Birgit , Niehaus Oliver , Rodewald Ute Ch , Alam Adel F. Al , Ouaini Naim , Poettgen Rainer 
Published: March 2015

AbstractPolycrystalline ScFe6Ge4 is prepared by arc melting of stoichiometric amounts of the elements from which single crystals are grown by annealing (muffle furnace, 970 K, 3 weeks).
ChemInform Abstract: The Gallium Intermetallics REPdGa3 (RE: La, Ce, Pr, Nd, Sm, Eu) with SrPdGa3‐Type Structure.
Authors: Seidel Stefan , Niehaus Oliver , Matar Samir F. , Janka Oliver , Gerke Birgit , Rodewald Ute Ch. , Poettgen Rainer 
Published: March 2015

AbstractLnPdGa3 (Ln: La, Ce, Pr, Nd, Sm, Eu) compounds are obtained by arc‐melting of the elements and subsequent annealing for crystal growth (evacuated quartz tubes, 700 K, 3 d).
ChemInform Abstract: Cotemplating Synthesis of a Rare Borate Ni(en)3·Hen· [B9O13(OH)4]·H2O with a Chiral Polyanonic Chain Constructed from Two Different Clusters.
Authors: Pan Chun‐Yang , Zhong Li‐Juan , Zhao Feng‐Hua , Luo Yuan‐Zhang , Li Da‐Guang 
Published: March 2015

AbstractThe title compound is prepared by solvothermal treatment of a mixture of H3BO3, NiCl2, DMF, en, and 3‐nitrophenylboronic acid in the respective molar ratio of 7.7:0.5:25.9:44.9:0.8 under the co‐templating effect of [Ni(en)3]2+ and Hen+ cations (autoclave, 128 °C, 7 d; 34% yield).
ChemInform Abstract: Enantioselective Aza‐Morita—Baylis—Hillman Reaction Between Acrylates and N‐Boc Isatin Ketimines: Asymmetric Construction of Chiral 3‐Substituted‐3‐aminooxindoles.
Authors: Zhao Xuan , Li Tian‐Ze , Qian Jing‐Ying , Sha Feng , Wu Xin‐Yan 
Published: March 2015

AbstractThe first enantioselective aza‐Morita—Baylis—Hillman reaction of acrylates with ketimines derived from isatins is developed.
ChemInform Abstract: Phosphine‐Catalyzed Annulations of 4,4‐Dicyano‐2‐methylenebut‐3‐enoates with Maleimides and Maleic Anhydride.
Authors: Zhang Xiao‐Nan , Chen Gen‐Qiang , Tang Xiang‐Ying , Wei Yin , Shi Min 
Published: March 2015

AbstractThe novel [4 + 1] annulation reactions of maleimides afford spirocyclic products whereas [3 + 2] annulation reactions of maleic anhydride provide functionalized cyclopentenones.
ChemInform Abstract: Atom Transfer Radical Cyclization of Trichloroacetamides to Electron‐Rich Acceptors Using Grubbs′ Catalysts: Synthesis of the Tricyclic Framework of FR901483.
Authors: Diaba Faiza , Martinez‐Laporta Agustin , Bonjoch Josep 
Published: March 2015

AbstractThe intramolecular Kharash‐type cycloaddition of trichloroacetamides provides access to 2‐azaspirodecanes (II), morphan derivative (IV), and the core structure (VI) of the immunosuppressant FR901483.
ChemInform Abstract: Organocatalytic Enantioselective Strecker Reaction of Imines Containing a Thiazole Moiety by Using a Cinchona‐Based Squaramide Catalyst.
Authors: He Hai‐Xiao , Du Da‐Ming 
Published: March 2015

AbstractThe benzothiazole moiety is crucial to achieve a high asymmetric induction and the reaction proceeds without any enantioselectivity for other heterocycles like thiazole or thiadiazole (not shown).
ChemInform Abstract: Synthesis of S,S,O‐Orthoesters and 1,1‐Difluoroalkyl Ethers via Reaction of Peroxides with Lithiated 1,3‐Dithianes.
Authors: Kyasa ShivaKumar , Dussault Patrick H. 
Published: March 2015

AbstractThe first example of intermolecular reaction of dialkyl peroxides with stabilized carbanions is demonstrated.
ChemInform Abstract: Copper‐Catalyzed Endo‐Type Trifluoromethylarylation of Alkynes.
Authors: Xu Jun , Wang Yun‐Long , Gong Tian‐Jun , Xiao Bin , Fu Yao 
Published: March 2015

AbstractThe unprecedented and new title reaction represents the first example of endo‐type carbotrifluoromethylation of unsaturated C—C bonds.
ChemInform Abstract: From Racemic Alcohols to Enantiopure Amines: Ru‐Catalyzed Diastereoselective Amination.
Authors: Oldenhuis Nathan J. , Dong Vy M. , Guan Zhibin 
Published: March 2015

AbstractAn effective method for chiral amine synthesis by combining the power of the widely used Ellman′s sulfinamide auxiliary with the practicality of the inexpensive and an industrially relevant Ru catalyst is developed.