bluuebunny/crossref_metadata_2025_split huggingface dataset:
Self-rated health of Latino day laborers during the COVID-19 pandemic: a cross-sectional study
Authors: Catindig Jan , Atkinson John , Llamas Ana , Fernandez-Es Maria Eugenia 
Published: August 2024

Abstract

Background: This study assesses the relationship between trust in sources of information in regard to the Coronavirus Disease 2019 (COVID-19) pandemic and self-rated health (SRH) in a sample of Latino Day Laborers (LDLs) and explores whether these associations were mediated by mental health measures.
Methods: A rapid needs assessment survey was conducted with 300 LDLs, recruited at randomly selected hiring locations in Houston, Texas, during November and December 2021. Two measures of trust were developed, and SRH was measured by a single item. Depression, anxiety, and stress were measured by previously validated scales. We applied the product of coefficients approach to assess our mediation model. Using Hayes’ PROCESS version 4.2 in SPSS, linear regression models were generated simultaneously to assess the total effect of trust on SRH, effect of trust on the mental health mediator, and effect of the mediator on SRH, controlling for trust. Demographic characteristics were entered as covariates.
Results: Greater trust in formal sources of information (such as Spanish-speaking television networks) as well as greater levels of anxiety and depression were associated with lower SRH. There were no significant associations between formal trust and mental health measures. As such, the association between formal trust and decreased SRH was not mediated by mental health. Trust in informal sources of information (conversations with friends, family, and coworkers) was not significantly associated with SRH or mental health. Higher levels of depression and anxiety, however, were associated with lower SRH.
Conclusions: LDLs’ perception of their health was inversely associated with their level of trust in formal sources of information and with greater levels of depression and anxiety. Nevertheless, these pathways were independent of each other. The results indicate the direct impact of COVID-19 public information on subjective well-being, a relationship that merits further exploration.
The 1 H, 15 N, and 13 C resonance assignments of a single-domain antibody against immunoglobulin G
Authors: Leite Vanessa Bezerra Oliveira , Andrade Rafael Alves , Almeida Fabio Ceneviva Lacerda , Nascimento Claudia Jorge , Araújo Talita Stelling , Almeida Marcius Silva 
Published: August 2024

Abstract

Research on camelid-derived single-domain antibodies (sdAbs) has demonstrated their significant utility in diverse biotechnological applications, including therapy and diagnostic. This is largely due to their relative simplicity as monomeric proteins, ranging from 12–15 kDa, in contrast to immunoglobulin G (IgG) antibodies, which are glycosylated heterotetramers of 150–160 kDa. Single-domain antibodies exhibit high conformational stability and adopt the typical immunoglobulin domain fold, consisting of a two-layer sandwich of 7–9 antiparallel beta-strands. They contain three loops, known as complementary-determining regions (CDRs), which are assembled on the sdAb surface and are responsible for antigen recognition. The single-domain antibody examined in this study, sdAb-mrh-IgG, was engineered to recognize IgG from rats, mice, but it also weakly recognizes IgG from humans (Pleiner et al. 2018). A search of the Protein Data Bank revealed only one NMR structure of a single-domain antibody, which is unrelated to sdAb-mrh-IgG. The NMR chemical shift assignments of sdAb-mrh-IgG will be utilized to study its molecular dynamics and interactions with antigens in solution, which is fundamental for the rational design of novel single-domain antibodies.
Investigations on Camouflage Reconnaissance in Multispectral Images through Machine Learning Algorithms
Authors: Hegde Abhilash , Nandibewoor Archana , Kulkarni Aachan B , Deshpande Anurag G , . Abushekh , Anantpur Bhairavi M 
Published: August 2024

Abstract

Camouflage Reconnaissance in Multispectral Images by utilizing Machine Learning algorithms will be the crucial task of identifying concealed camouflaged objects. Essentially this can be applied for various fields including security, military operations, and environmental monitoring. Using Altum-PT multispectral camera, the diverse dataset of multispectral images was collected and processed. This involves employing techniques such as fusion, Numpy false colouring, and pansharpening etc. to enhance image quality and to extract relevant features. The aim of this investigation revolves around detecting concealed camouflaged objects using advanced deep learning models, specifically You Only Look Once (YOLO) V5, V7, V8, V9 and Slicing Aided Hyper Interference (SAHI). These models have been assessed for their effectiveness accurately by identifying concealed objects across different environmental contexts. Furthermore, the work includes a comparative study where the results obtained from each model are analyzed and compared. This provides valuable insights into the strengths and weaknesses of individual models in the context of camouflage reconnaissance. Therefore, this investigation will become an advancement in enhancing surveillance capabilities by contributing to improved situational awareness and security across various domains.
Designing a convolutional neural network to classify eletronic component defects in PCBs
Authors: Bauchspiess Ricado , Ferreira Genilson , Soares Karen , de Araújo Livia Fernanda Lobão 
Published: August 2024

Abstract

Assembly of electronic components in printed circuit boards(PCBs) is prone to errors which require timely identification, which is usually done through automated optical inspection (AOI) methods. Recent developments have proposed the use of convolutional neural networks (CNNs) to perform inspections in industrial settings. CNN however have a limitation in which a large amount of data is required, which is particularly challenging for electronic component defect recognition, since defective samples are more difficult to obtain. In this work we propose a new CNN architecture for electronic component defect classification, using a two stage transfer learning model training approach to deal with the low amount of data problem. We tested our approach on a dataset of electronic components for defect classification, obtaining 99.45\% accuracy, outperforming other popular neural network models.
Targeting modulation of the choroid plexus blood-CSF barrier and CSF hypersecretion via lipid nanoparticle-mediated co-delivery siRNA and resveratrol
Authors: Gao HuiLe , Wang Qiguang , Xia Xue , Zhang Huan , Li Yue , Zhu Lei , Shi Yulong , Tang Yuzhao , Cheng Jian , Hui Xuhui 
Published: August 2024

Abstract

Hydrocephalus is one of the most common neurological disorders, but pharmacotherapy options are currently lacking due to the complex pathogenesis. The blood-CSF barrier (B-CSFB), consisting of choroid plexus (ChP) epithelial cells, is a crucial gate for the entry of peripheral immune cells and its dysfunction emerges as a new contributor to hydrocephalus pathology. Meanwhile, SPAK-mediated CSF hypersecretion in ChP epithelial cells plays an important role in the pathogenesis of hydrocephalus. Here, we fabricated a transferrin receptor-targeted nano-drug (siR/RSV@TNP) that can intelligently navigate to the blood-CSF barrier and prepared for combined delivery of resveratrol (RSV) and SPAK siRNA (siSPAK)for synergetic hydrocephalus therapy. As expected, siR/RSV@TNP fulfilled its function of knocking down SPAK expression, relieving inflammation and oxidative stress, retrieving blood-CSF barrier integrity, and ultimately preventing ventriculomegaly and hydrocephalus. The current study demonstrates proof of concept that targeting the choroid plexus blood-CSF barrier and cerebrospinal fluid hypersecretion offers a promising and innovative approach for alleviating hydrocephalus.
The Four-Item Mentalising Index (FIMI): A multinational validation of the Arabic version in 12 countries
Authors: Fekih-Romdhane Feten , Ali Amira Mohammed , Alhuwailah Amthal , Sakr Fouad , Chaibi Leila Sarra , Helmy Mai , Shuwiekh Hanaa Ahmed Mohamed , Boudouda Nedjem Eddine , Zarrouq Btissame , Naser Abdallah Y , Taybeh Esra’ O. , Jebreen Kamel , Roubi Mohammed Lakhdar , Hassan Bassam Abdul Rasool , Merdad Nisma , Amin Rizwana , Nawajah Inad , Mohammed Ali Haider , Farhan Sinan Subhi , AlAni Omar Abdulwahid , Dabbous Mariam , Malaeb Diana , Obeid Sahar , Cheour Majda , Shah Punit , Hallit Souheil 
Published: August 2024

Abstract

Background: The lack of sound measures to assess mentalising in Arabic-speaking adults is a significant gap that can substantially constrain understanding of the expression and difficulties in the mentalising processes across the lifespan in the Arab world, and of the cross-cultural. Therefore, this study aimed to investigate the psychometric properties of an Arabic translation of the FIMI in a multi-national sample of non-clinical adults.
Methods: A sample of 8,408 adults (74.5% females, mean age 24.70 ± 8.44 years) from the general population of twelve Arab countries was surveyed to examine the psychometric properties of the Arabic FIMI.
Results: CFA indicated that fit of the one-factor model of FIMI scores was excellent: RMSEA = .035 (90% CI .023, .048), SRMR = .012, CFI = .996, TLI = .989, and had adequate internal consistency reliability (ω = .68; α = .65). Indices suggested that configural, metric, and scalar invariance was supported across sex and country groups. Finally, correlational analyses provided support for construct validity of the Arabic-language version of the FIMI, by showing significant positive correlations between mentalising and self-reported autistic traits scores.
Conclusion: Findings suggest that the Arabic FIMI is valid, reliable ad suitable for use among Arabic-speaking adults. The scale may raise awareness among clinicians and researchers of the possibilities to easily and accurately assess mentalising in order to enable the development, testing and monitoring of tailored Mentalising-based treatments aimed at addressing impaired mentalising and managing a range of mental disorders in Arab settings.
Identification of Damage to Wood Pillar Foundations for Repairing House Construction Damage on Swampland
Authors: Agusniansyah Nursyarif 
Published: August 2024

Abstract

House construction is a unique characteristic of the swamp lands in Banjarmasin. Foundations for swampy soil require special handling. The weakness of wood materials and the inability of wood pillar foundations to support building loads are the primary causes of building problems in these swampy areas. Mistakes in foundation construction often arise from the need to expand houses to two stories or renovations. The load-bearing capacity of the wood pillar foundations used is very limited. This study aims to determine the weaknesses of wood pillar foundations to address signs of damage in house construction on swamp land. Field observation research, including the examination of house buildings and individual objects, was conducted at several construction sites in Banjarmasin as part of this study. Data presentation is descriptive. The results indicate that weak wood pillar foundation construction is characterized by damaged piles and floor subsidence. The small size of the wood pillars also limits the load-bearing capacity. The presence of broken 'sunduk' elements is one of the causes of this foundation damage. This research provides new insights into the weaknesses of wood pillar foundations and offers repair recommendations to enhance the resilience and stability of buildings on swamp land.
Seasonal natural organic matter removal and implications for disinfection by-product formation at the Koka water treatment plant: Upper Awash, Ethiopia
Authors: Assefa Emeru , Jabasingh Anuradha , Tadesse Abi M. , Dessalegne Meseret , Mulugeta Eyobel , Teju Endale 
Published: August 2024

ABSTRACT

This study evaluated the seasonal performance of the Koka water treatment plant in removing natural organic matter (NOM) and the implications for disinfection by-product (DBP) formation potential. Raw and treated water samples were collected during the dry and wet seasons and analyzed using physicochemical parameters and fluorescence spectroscopy. The results revealed significant seasonal variations in raw water (RW) quality, with higher turbidity, pH, temperature, conductivity, total organic carbon (TOC), dissolved organic carbon (DOC), and UV254 absorbance during both seasons and across treatment processes. The NOM removal efficiency of the treatment plant was poor, with mean TOC removal of 46 and 43% and DOC removal of 15.8 and 15.2% during dry and wet seasons, respectively. The sedimentation unit demonstrated negative TOC removal, indicating NOM accumulation likely due to biochemical reactions in the unit. Fluorescence analysis and the correlation between specific ultraviolet absorbance (SUVA) and DBP formation potential suggest a higher risk of DBP formation in chlorinated drinking water. These findings highlight the influence of seasonal variations, RW quality, and the treatment process dynamics on the plant's performance in removing NOM. There is a need to implement adaptable strategies to enhance NOM removal, accounting for seasonal fluctuations in RW quality.
Sinodalidad y ecumenismo la formación ecuménica aporta a la formación sinodal
Authors: Merino Patricio 
Published: August 2024

Este artículo destaca la relación entre sinodalidad y ecumenismo, además, de la necesidad de la formación del Pueblo de Dios. Pero, sobre todo, nos centramos en las posibilidades de la formación ecuménica, que igualmente contribuye a la formación sinodal. Para ello, analizaremos algunas ideas de documentos que relacionan sinodalidad y ecumenismo. Tales como, Comisión Teológica Internacional: “La sinodalidad en la vida y la misión de la Iglesia” (2018). También, el “Vademécum Ecuménico” del Pontificio Consejo para la Promoción de la Unidad de los Cristianos (2020); y el “Informe de Síntesis” de la XVI Asamblea General Ordinaria del Sínodo de los Obispos en su Primera Sesión (2023). Luego nos centramos en la presentación de un instrumento importante para la formación ecuménica, como lo es el libro aparecido recientemente titulado: Caminar Juntos: Manual de Ecumenismo (2023). Todo con la finalidad de llamar la atención de la vigencia del diálogo ecuménico en el cristianismo católico involucrado en procesos que lleven a una Iglesia más sinodal.
Synthesis and Evaluation of Cytotoxicity of Carbon Dots Functionalized with Diosgenin
Authors: Karimi Niloufar , Sharififar Fariba , Ranjbar Mehdi , Farsinejad Alireza , Mohajeri Mohammad , Karami-Mohajeri Somayyeh , Mandegar Ali , Majd Faranak Nasiri 
Published: August 2024

Background:
Diosgenin is a plant-derived steroidal sapogenin, whose effectiveness has
been reported in the treatment of various cancer cells, but its poor bioavailability has always been
a limiting factor. Carbon dots are very small nanoparticles with high reactivity and the ability to
functionalize with various materials. In this study, by functionalizing carbon dots with diosgenin,
we sought to evaluate its cytotoxicity.

Materials and Methods:
The physicochemical characteristics of carbon dots synthesized by the
hydrothermal method were investigated by DLS and SEM techniques. Then, the carbon dots were
functionalized with diosgenin. The rate of cell viability and apoptosis on the 3T3 and MCF-7 cell
lines were measured after treatment with different concentrations of carbon dots functionalized
with diosgenin.

Results:
According to the flow cytometry data, carbon dots functionalized with diosgenin induced
more cytotoxicity compared to free diosgenin in both 3T3 and MCF-7 cell lines through induction
of apoptosis.

Conclusion:
According to the results, the use of carbon dots functionalized with diosgenin causes
more cytotoxic effects than free diosgenin. We speculate that this increase in cytotoxicity is probably
due to the increased permeability of diosgenin, followed by intense induction of apoptosis.

result:
According to the flow cytometry data, carbon dots functionalized with diosgenin induced more cytotoxicity compared to free diosgenin in both 3T3 and MCF-7 cell lines through induction of apoptosis.
Exploring Novel Therapeutic Avenues: Drug Repurposing for Neurodegenerative Movement Disorders
Authors: Bassi Pallavi , Rana Shivani , Sapra Vaibhav , Raina Ankita , Kumar Parveen , Devi Sushma 
Published: August 2024

Abstract:
Neurodegenerative movement disorders, encompassing conditions such as Parkinson's
disease, Huntington's disease, and amyotrophic lateral sclerosis, represent a significant
burden on individuals, families, and healthcare systems globally. Traditional drug discovery
approaches for these disorders have encountered challenges, including high costs and lengthy
timelines. Drug repurposing has emerged in recent years as a promising approach to expedite
the discovery of new treatments by leveraging existing drugs approved for other indications.
This review explores the landscape of drug repurposed for neurodegenerative movement disorders,
highlighting promising candidates, underlying mechanisms, and clinical implications. The
rationale behind repurposing, including the advantages of utilizing existing pharmacological
agents with established safety profiles and known pharmacokinetics, along with techniques utilized
for repurposing (computational and experimental), have been elaborated. Several studies
on the potential of pre-existing drugs such as isradipine, tetracycline, ambroxol, metformin, deferiprone,
simvastatin, etc., which have been repurposed for neurodegenerative movement disorders,
including Parkinson’s disease, Huntington’s disease, Alzheimer’s disease, Multiple
Sclerosis, etc. have been discussed. Further, the current scenario and future prospective of drug
repurposing have also been touched upon.
ANALISIS DETERMINAN INTERNAL YANG MEMENGARUHI PROFITABILITAS BANK-BANK DENGAN ASET TERBESAR TAHUN 2015-2022
Authors: Sitanggang Yohana Damaris , Wildana Muhammad Dandy Alif 
Published: August 2024

Covid-19 had raised concerns among investors, leading to a decline on the stock price. Banks had successfully restored investors confidence by maintaining their profitability. This research aims to see how banks manage internal banking resources to achieve optimal profits by determining the influence of assets, capital, deposits, loans, and Operational Efficiency Ratio (BOPO) on Return on Assets (ROA) of banks during the Covid-19 Pandemic. The data used in this study are Bank BRI, Mandiri, BNI, BCA, BTN, and BSI’s quarterly financial reports from 2015-2022. The research method employed is panel data analysis using random effect model. The result of the analysis indicates that capital and BOPO significantly affect ROA, while assets, loans, and deposits do not significantly influence ROA. Simultaniously, the variables of assets, capital, deposits, loans, and BOPO collectively affect ROA.
PENGARUH SER TERHADAP ROE DAN EPS EMITEN INDUSTRI KEUANGAN TAHUN 2013-2019
Authors: Arifiandy Dicky Ridho , Ekawaty Marlina 
Published: August 2024

Indonesia is a country with the largest Muslim population in the world. This makes Indonesia have great potential in developing the Islamic financial sector. In fact, Indonesia hasn't been able to maximize its potential. One of the sharia investment that shows positive developments is Sukuk. This study aims to analyze the effect of Sukuk to Equity Ratio on Return on Equity and Earning Per Share of issuers on the Indonesia Stock Exchange in 2013-2019. This study uses regression analysis to panel data with quantitative method. The results of this study indicate that the Sukuk to Equity Ratio has a significant positive effect on Return on Equity and Earning Per Share. These results are in accordance with the hypothesis formulated in this study.
PENGARUH LABEL HALAL, PERSEPSI HARGA, DAN PENDAPATAN TERHADAP KONSUMSI PRODUK OBAT BATUK (Studi Kasus di Wilayah Kota Malang)
Authors: Trihatmojo Gandhi Raka , Muljaningsih Sri 
Published: August 2024

This research is aimed to discover whether or not there is an effect of Halal labels, price perception as well as income levels on cough medicine consumption. The subject of this research are the 123 residents of Malang city, East Java using quantitative methodology. According to the results of this research, there is a positive relationship in between the effect of Halal label, price perception, plus income levels and cough medicine consumption. Of all independent variables, the one that gives the most significant effect is the presence of Halal labels. With that being said, this research suggests that the government or Islamic religious authorities accelerate Halal certification on cough medicines, as well as medicine manufacturers to increase affordable yet high quality cough medicine productions so that the public can have equal access to the medicine’s benefits
Kata Kunci: Halal, Obat Batuk, Harga, Penghasilan
Pengaruh Kualitas Produk dan Kepercayaan Konsumen Terhadap Kepuasan Konsumen Produk Genteng
Authors: Anggoro Muhammad Dwi Firmansyah Priyo 
Published: August 2024

Roof tile products from PT Varia Usaha Beton in Sidoarjo are part of the brick masonry or lightweight concrete product category. The company is a key player in the construction sector with a high reputation for product and service quality. In the midst of rapid technological developments and innovation, how do companies face intense competition and manage product quality, especially concrete roof tiles. This research aims to determine the influence of product quality and consumer trust on consumer satisfaction with roof tile products at PT Varia Usaha Beton Sidoarjo. The type of research used in this research is quantitative research. In calculating the sample using the Slovin formula, we obtained 105 respondents. The sampling technique used was a non-probability sampling technique using Purpositive Sampling. Researchers tested research data using descriptive analysis, multiple regression analysis, and hypothesis testing. The research results show that product quality and consumer trust partially and simultaneously have a significant and positive effect on consumer satisfaction.

Abstrak
Produk genteng dari PT Varia Usaha Beton di Sidoarjo merupakan bagian dari kategori produk beton masonry atau beton ringan. Perusahaan ini merupakan pemain kunci dalam sektor konstruksi dengan reputasi tinggi dalam kualitas produk dan pelayanan. Di tengah perkembangan teknologi dan inovasi yang cepat bagaimana perusahaan menghadapi persaingan ketat dan mengelola kualitas produk, khususnya genteng beton. Adapun untuk penelitian ini bertujuan untuk mengetahui pengaruh kualitas produk dan kepercayaan konsumen terhadap kepuasan konsumen produk genteng pada PT Varia Usaha Beton Sidoarjo. Jenis penelitian yang digunakan dalam penelitian ini adalah penelitian kuantitatif. Dalam perhitungan sampel yang diterapkan meggunakan rumus slovin, sehingga didapatkan sebanyak 105 responden. Teknik pengambilan sampel yang digunakan adalah teknik non-probability sampling dengan memakai purpositive sampling. Peneliti melakukan pengujian data penelitian dengan menggunakan analisa deskriptif, analisis regresi berganda, dan uji hipotesis. Hasil penelitian menunjukkan bahwa kualitas produk dan kepercayaan konsumen secara parsial dan secara simultan berpengaruh signifikan dan positif terhadap kepuasan konsumen.