bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Previous Hip Arthroscopy on Results after Hip Arthroplasty: Systematic Review and Meta-Analysis
Authors: Asal Mohamed Kamal , Mounir Ayman Fathy , Moris Georgeos Gerges Salah 
Published: July 2024

Abstract

Background
Hip arthroplasty is the most frequently performed adult reconstructive hip procedure. Total hip arthroplasty (THA) is one of the most successful procedures performed in modern orthopedics. The primary indication for THA in a patient with endstage arthropathy is pain resulting in significant limitation of physical activity. Important factors to be considered in the decision to recommend or undergo THA are patient age, diagnosis, and medical comorbidities.

Aim of the Work
This review pursues to systematically review the current evidence in the literature to determine whether previous hip arthroscopy would direct to inferior results in patients undergoing succeeding hip arthroplasty.

Patients and Methods
The first literature search identified 412 studies in total. After removing duplicates, 307 articles were deemed irrelevant based on their title and Abstractscreening. Eighty- two papers were eliminated from the remaining 105 research based on their title and Abstract. After carefully reviewing the entire text of all remaining publications, 11 studies were eliminated for reasons such as conference Abstracts, reviews, and lack of comparison between intervention and control groups. Additionally, one cohort research that compared THA results in patients who had previously undergone hip salvage surgery to those who had not previously undergone hip salvage surgery was removed. Finally, eleven studies spanning the years 2012 to 2019 were available for meta-analysis.

Results
Of these citations could result from the studies’ varying designs and sample sizes. Estimated blood loss, on the other hand, was deemed a reasonable indicator of operating time. The consistency in blood loss between the groups may reflect a similar operative time.

Conclusion
Patients who have previously undergone hip arthroscopy are more likely to experience postoperative complications such as dislocation, revision, and reoperation following subsequent hip arthroplasty. On the other hand, prior hip arthroscopy did not appear to affect functional or intraoperative results.
Application of Autologous Bone Graft versus Non Grafting in Medial Opening Wedge High Tibial Osteotomy Less than 14 mm: A Systematic Review and Meta-Analysis
Authors: Moneim Eid Mohamed Abdel , Zakaria Zeiad M , Fahim Mohamed ELSokkary Ahmed Mamdouh 
Published: July 2024

Abstract

Background
Unicompartmental Knee osteoarthritis KOA due to varus malalignment is increased in young active patients which occurs predominantly in the medial compartment.

Aim of the Work
The objective of this study to compare MOWHTOs with autologous bone graft and without bone graft (wedge space mean less than 14 mm) in treatment of unicompartmental KOA and varus malalignment of the knee to determine which is better in decision-making according to outcomes.

Patients and Methods
Studies that matched the inclusion criteria were included in this meta-analysis. participants with medial compartmental knee osteoarthritis and varus malalignment were shown in the investigation. The age of the participants was unrestricted. Plate as a fixation method was the only option regardless of plate type. During 2000 and 2021, a research study of internet databases (Egyptian Universities Research, Medline, PubMed, Cochran library, medical journals) was conducted. Following that, the references from the user research were examined, and specialists were approached for assistance in locating other papers. Two independent reviewers extracted data separately and cross-checked it.

Results
The Knee Society Knee score (KSKS) and Knee Society Function score (KSFS) are most commonly used for the assessment of the knee joint reveled that there is no statically significant difference between bone graft vs non graft. Regarding this systematic review the radiological outcomes, the clinical bone union and the full weight bearing movement, are rendering any statistical analysis meaningless. Regarding complications presented, there was a similar tendency for complication rate when compared according to grafting or non- grafting. The use of autograft accelerates radiographic healing of the osteotomy gap after OWHTO while shorten the union time but confers no advantages in terms of functional or patient elated out comes at 3 or 12 months postoperatively.

Conclusion
MOWHTO can be performed without a graft with less operative time and avoiding graft harvest comorbidity with similar clinical and radiological results regarding bone union and posterior tibial slope alteration and knee scores.
Fixation Vs Arthroplasty for Management of Geriatric Distal Femur Fractures
Authors: Khalil Gendya Amr Gamaleldin Mahmoud , El-Zaher El-Zaher Hassan , Zakaria Zeiad Mohamed , Abdelhamid Metwaly Radwan Gamal Eldeen , El Sayed Awad Mohamed 
Published: July 2024

Abstract

Background
Distal femur fractures are considered challenging to manage, particularly in geriatric patients. Double plating (DP) is a technique that helps with earlier rehabilitation and return to pre-injury level of activity. Distal femoral replacement (DFR) is an alternative technique in the management of these fractures that may help to solve problems like associated knee osteoarthritis, osteoporosis, and severely comminuted condyles. The current study compares the functional and radiological outcomes of DFR and DP in the management of these fracture among geriatric patients.

Methods
This randomized, comparative, interventional study was performed at a university hospital. A total of 30 patients who underwent DFR or DP after distal femur fractures (AO/OTA 33 A3, 33 C) were analyzed. The primary outcome was Knee Society Score (KSS), whereas secondary outcomes included postoperative complications rate, knee range of motion (ROM), reoperation rate, and operative time.

Results
No significant difference was observed between DFR and DP except for the knee component of the KSS at 12-month interval (p = 0.03), and knee ROM at 12-month interval (p = 0.001), both of which were in favor of DP. No significant difference in postoperative complications (p = 0.06), reoperation rate (p = 1.00), or operative time (p = 0.06) were noted.

Conclusion
DFR and DP had comparable functional (KSS) and radiological outcomes with no significant difference in postoperative complications, reoperation rate, or operative time.
Management of Proximal Femoral Metastasis “Systematic Review/Meta-Analysis”
Authors: Fahmy Ibrahim Fady Micheal , El Mowafi Mohamed Ahmed , Ahmed Assem Bastawisy , Alian Zidan Alaa Ragab 
Published: July 2024

Abstract

Background
Adequate treatment of patients with proximal femur metastases demands higher level of attention due to the increasing life expectancy, and the need of maintaining good functional integrity and quality of life. In the presence of impending or actual pathologic fracture, treatment requires a reconstruction which provides pain control, stable and secure fixation and allows for immediate weight-bearing.

Objective
to evaluate management of proximal femoral metastasis as regards: functional outcome, oncological outcome and complications.

Material and Methods
This systematic review was conducted on human subjects in different literatures collected from different medical websites before 2022 in which we compared osteosynthesis including IMN (group 1) and reconstruction whether endoprosthesis replacement, total hip arthroplasty or hip hemiarthroplasty (group 2) in treatment of proximal femoral metastasis.

Results
Osteosynthesis results in a high recurrence, failure rate and non-union, while Dislocation rates and infections were common in reconstruction. the survival rate was prolonged in reconstruction than in osteosynthesis by IMN.
The Lateral Sinus Tarsi Approach in Fixation of Displaced Intra-Articular Calcaneal Fracture. A Systematic Review & Meta Analysis
Authors: El-beltagy Atef Mohmad , Abdel-Wahab Mahmoud Mohammed , Mosaad Abanoub Nabil 
Published: July 2024

Abstract

Background
Minimally invasive reduction and fixation techniques via a sinus tarsi approach (STA) have been developed in an attempt to avoid the potential complications associated with an extensile lateral approach (ELA) and to be less invasive.

Objective
Minimally invasive approach including sinus tarsi approach (STA) in displaced intra articular calcaneal fracture displaced intra-articular calcaneal fractures (DIACF) with reference to: Change from baseline in calcaneal height, change from baseline in calcaneal width, change from baseline in calcaneal length, change from baseline in Bohler angle, change from baseline in Gissane angle.

Methodology
This meta-analysis was carried out in accordance with the Cochrane Handbook of Systematic Reviews of Intervention and Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines to answer the question of minimal invasive of lateral sinus tarsi in displaced intra articular calcaneal fracture. The study protocol was registered into the International Prospective Register of Systematic Reviews on September 09, 2020 with a registration number (PROSPERO: CRD42022359197).

Results
Running our search strategy on PubMed 69 studies, and the Cochrane library resulting in 221 studies and trials. We discarded 12 studies after screening the title and Abstract. Then we screened 18 studies to assess their eligibility for inclusion; and in last 10 years. The total sample size for this meta-analysis was 12 participants. 484 patients who completed STA surgery and 514 patients completed ELA surgery.

Data Sources
Medline databases (PubMed, cochrane) and all materials available in the Internet till 2023.

Conclusion
In conclusion, using the minimally invasive sinus tarsi approach (STA) is associated with a significant change in calcaneal height and Gissane angle when compared to extended lateral approach (ELA) when used to manage the displaced intra-articular calcaneal fractures (DIACF).
Compliance and Ketones Levels in Relation to Seizure Control in Children with Drug Resistant Epilepsy Treated with Ketogenic Diet
Authors: Shatla Hamed M , Elgendy Yasmin G , Shata Mennatallah O , Ibrahim Haya E , Mohammed Tasneem M 
Published: July 2024

Abstract

Background
The ketogenic diet (KD) is a high-fat, adequate-protein, low-carbohydrate diet. Ketogenic diet therapy (KDT) has become an important option in the management of drug- resistant epilepsy and some of the inborn errors of metabolism in children, with increasing evidence of its favorable effects.

Objective
To evaluate patient's compliance to KD in children with drug resistant epilepsy (DRE) and the effect of KD on course and outcome of DRE.

Methodology
This cross-sectional study included 42 children whose age ranged between 1 month and 18 years with drug resistant epilepsy (DRE) on ketogenic diet for at least 3 months. They were recruited from the Ketogenic Diet Clinic, Children’s hospital, Ain Shams University, Cairo, Egypt. They were assessed for anthropometric measurements, betahydroxybutyrate (BHB) in blood,and acetone in urine, fasting lipid profile,serum random blood sugar;The frequency and severity of convulsions were assessed using chalfont severity scale before and after applying KD and correlated with the laboratory markers measured.

Results
Beta hydroxybutarate levels in blood ranged from (0.1 - 4.6) achieving ketosis in 37patient (BHB&gt;2 mmol/L). As regard frequency of convulsions per day there was highly significant decrease after 3 month of KD with p &lt; 0.001 compared to that before using the KD. On applying chalfont seizure severity scale on our patients there was highly significant decrease in the severity of the seizure with p &lt; 0.001 after KD. Regarding the frequency of possible complications associated with KD, 69% of the patients had no complication, while 26.2% had constipation, 26.2% had hyperlipidemia, 2.4 % had vomiting, 2.4 % had kidney stones, and 2.4 % had urinary gravels.

Conclusion
KD is an effective, safe, and tolerable therapy for children with DRE where significant improvement in both frequency and severity of seizures after KD were found.
Value of Transabdominal Sonographic Rectal Diameter in Children with Functional Constipation
Authors: Boules Ireny Sefain , Hamdy Ahmed Mohamed , El Sayed Sakr Hossam Moussa , Awad Yosra Mohsen 
Published: July 2024

Abstract

Background
Constipation is a common problem worldwide. Since rectal digital examination and abdominal radiography have both limitations, ultrasound is considered an alternative technique, thus the aim of the current study is measurement of rectal diameter among a group of children with functional constipation (FC) in comparison with a healthy control group to determine the diagnostic efficacy of dilated rectal diameter for diagnosis of constipation.

Patients and Methods
A case control study that was conducted on children aged between 2 and 10 years; 50 were cases with functional constipation who were recruited from gastroenterology department and an equal number of age and sex matched apparently normal and healthy children were included as a control. FC was diagnosed according to the ROME IV criteria. Pelviabdominal ultrasound was done to all cases and controls to assess the rectal transverse diameter after taking detailed history regarding personal history, symptoms and history of present illness, past history and family history.

Results
Rectal diameter was measured in cases initially on presentation where 80% of the cases had enlarged rectal diameter, and 20% of cases had normal rectal diameter, ranging from 1.6 cm to 4.7 cm with a median of 3.55, while only 8% of controls has enlarged rectal transverse diameter and others were normal (P value &lt;0.001).

Conclusion
based on our results, it can be concluded that rectal diameter is. significantly enlarged in most cases with constipation.
COVID-19 in Egyptian Children on Regular Hemodialysis: Experience of a Single Center
Authors: Elmoselhy Sawsan Sayed , Ali Said Ragia Marei , Darweish Sallam Dina Ebrahem , Manzour Ayat Farouk , Abdelnabi Hend Hassan , Abozahra Alaa Ali 
Published: July 2024

Abstract

Background
COVID-19 is clinically characterized by high rates of transmission, and pathological abnormalities. Pediatric patients with CKD are at high risk of COVID-19 infection & morbidity.

Aim of the Work
We aimed at studying the rate of infection by COVID-19 in pediatric patients following up at our Pediatric dialysis & Nephrology unit, Ain Shams University.

Patients and Methods
This retrospective study was conducted over 12 months from 1st of March 2020 to end of February 2021 on 70 pediatric patients with chronic kidney disease stage 5 on regular hemodialysis (CDK5d).

Results
The mean age & dialysis duration of our studied patients was 11.89 (±3.01) years & 2.17(±1.2)years respectively, where the incidence of COVID-19 infection confirmed by PCR on nasal swab sampleswas 7%. The younger patients had a higher rate of COVID-19 infection than older ones (p = 0.05). Using public transportation during past 14 days before getting COVID-19 infection was significant in COVID-19 positive patients (p = 0.01). The common associated symptoms in our patients were fever, joint ache, muscle ache, loss of appetite, headache, shortness of breath, fatigue, cough, sore throat, nausea, loss of smell or taste, diarrhea, vomiting.

Conclusion
COVID-19 infection among our CDK5d patients was not uncommon with incidence of 7%, where younger patients were infected more frequently than older patients The common associated symptoms in our patients were fever, joint ache, muscle ache, loss of appetite, headache, shortness of breath, fatigue, cough, sore throat, nausea, loss of smell or taste, diarrhea, vomiting.
COVID-19 Pandemic Effects on Epileptic Children and Interleukin 6 Levels in Recently Diagnosed Epileptic Patients: A Cross Sectional Study
Authors: Zaky Eman Ahmed , Maher Deifalla Shaymaa Ahmed , Ahmed Taher Omnia Mohamed Elnabawy , Shatta Mennatalla Osama , Abdelmageed Reham Ibrahim 
Published: July 2024

Abstract

Background
Epilepsy is a disease with wide range of definitions. It is considered a multifactorial condition that may present at various ages and in many forms, which makes it challenging for physicians. In late 2019, SARS-CoV-2 (COVID-19) emerged as a novel coronavirus. Both epilepsy and COVID-19 can be linked in more than one way.

Aim of the Study
To Determine the effects of COVID-19 pandemic on the health-related quality of life and psychosocial aspects of children with epilepsy & to Determine whether COVID-19 infection is an inflicting cause for epilepsy in newly diagnosed cases.

Patients and Methods
We interviewed 50 patients with Epilepsy and their parents, for the blood tests we sampled 40 and 40 close relatives with no medical condition of similar age and sex.

Results
50 subjects’ results were demonstrated, 28 males and 22 females, median age was 9 years old. Unfortunately, almost all were experiencing depression, data showed that 1 (2%) didn’t have depression, 15 (30%) had mild depression, 27 (54%) had moderate depression and 7 (14%) had been experiencing severe depression, Mostly, all in our study were experiencing anxiety, data showed that 1 (2%) didn’t experience anxiety, 7 (14%) experienced mild anxiety, 16 (32%) experienced moderate anxiety while 26 (52%) experienced severe anxiety. Fair physical, social and emotional health overall, data showed that the average physical health quality of life was 450 (SD 197.65), the average emotional health quality of life was 275 (SD 126.91), the average social health quality of life was 275 (SD 123.61) and the average school performance quality of life was 287.5 (SD 154.31). There were 9 cases newly diagnosed with epilepsy who were COVID IgM. Among subjects with COVID IgM positive, 3 (25%) had no neurological manifestations. Cases had higher levels of IL-6 compared to control children 187.5+/-68.89 and 77.33+/-27.94 respectively with statistically significant difference p &lt; 0.001. However, no significant difference was found upon comparing COVID IgM levels of the 2 relevant groups.

Conclusion
COVID-19 pandemic has major impacts on health-related quality of life, causing depression, anxiety, decreased social and physical activities and poor school performance. COVID-19 can cause new onset seizures and epilepsy, or increase the frequency of seizures, IL-6 is a useful marker for severity of diseases as COVID-19, also for following up the progression of the disease, but not a marker for diagnosing it.
Functional Mobility Scale and Scoliosis Degree before and after Zoledronate Therapy in Children with Osteogenesis Imperfecta
Authors: Elsedfy Heba Hassan , Amr Nermine Hussein , Khalaf Randa Ismail , Aly Baraka Mostafa Mohamed , Fawaz Shereen Ismail , Mohamed Abouelnasr Marwa Abdelhamid 
Published: July 2024

Abstract

Background
Intravenous zoledronate, has been indicated for the treatment of Osteogenesis imperfecta (OI). It is a heritable disorder that causes bone fragility. The purpose of this study was to evaluate its effect on functional mobility scale and scoliosis degree on children with OI.

Methods and Results
This observational study was conducted on 28 OI patients (12 boys & 16 girls) aged 1.3-7.15years. All parameters were evaluated at Pediatric Endocrinology clinic, Children’s Hospital, Ain Shams University. Treatment was started with zoledronate dose 0.05 mg/kg every 6 months. Children less than 3 years of age received intravenous Zoledronate at a dose of 0.025 mg/kg per dose every 6 months with a maximum dose of 2 mg, while children above 3 years old received 0.05 mg/kg/dose every 6 months with a maximum dose of 4 mg. FMS and scoliosis degree using cobb anglewere evaluated before and after zoledronate therapy. Patients showed highly significant improvement in FMS. Patients with mild and moderate degree of scoliosis showed a non significant improvement in the degree of scoliosis while patients with severe scoliosis didn’t show any statistically significant difference.

Conclusion
Our study showed that intravenous zoledronate treatment, given once every 6 months, is an effective mode of treatment in OI children. It was associated with improvement in FMS. Longer follow-up is necessary to monitor the effect of treatment on degree of scoliosis by cobb angle.
Assessment of Anthropometric and Pubertal Growth of Children and Adolescents with Type 1 Diabetes Mellitus
Authors: Sherif Eman Monir , Thabet Rasha Adel , Ahmed Mahmoud Rana Abdelhakim , Abd El-aal Ahmed Mohamed Osman 
Published: July 2024

Abstract

Background
Type 1 diabetes mellitus (T1DM) is a wasting disease which is characterized by a severe deficiency or absence of insulin. It can interfere with growth and pubertal development, especially in uncontrolled patients with diabetes.

Aim of the Work
Our primary aim was to assess the anthropometric measures and pubertal growth of children and adolescents with T1DM regularly attending Pediatric and Adolescents Diabetes Unit (PADU), Ain Shams University. Our secondary aim was to detect risk determinants affecting these measures and their link to glycemic control.

Patients and Methods
This cross-sectional observational study was carried out on 200 children and adolescents with T1DM attending the PADU clinic. Patients were assessed using anthropometric measurements, lipid profile (Fasting serum triglycerides, total cholesterol, HDL and LDL) and HbA1c%. Those with short stature were further evaluated using insulin like growth factor1 (IGF1), bone age, lipid profile and thyroid profile. while those with delayed puberty were evaluated using sex hormones.

Results
we found that 12.5% of our patients were short (SD&lt;-2), Cut off point of IGF-1 SDS (≤ -1.2) and GF1( 2ng/ml) was low in72% of them. Diabetic patients with short stature have significantly earlier age of onset of diabetes, earlier age at diagnosis and longer duration of diabetes compared to those with normal stature (P &lt; 0.05). Additionally, patients with short stature and those with delayed puberty have higher HbA1c. Patients with short stature also have higher lipid profile and lower IGF1 compared to those with normal stature (p &lt; 0.05).

Conclusion
Children with uncontrolled T1DM are at risk of being short and had delayed puberty. IGF-1 level can be used as a screening test for short stature in diabetic children.