bluuebunny/crossref_metadata_2025_split huggingface dataset:
Muscle activity and hypoalgesia in blood flow restricted versus unrestricted effort‐matched resistance exercise in healthy adults
Authors: Yang Jinghui , O'Keeffe Rory , Shirazi Seyed Yahya , Mehrdad Sarmad , Atashzar S. Farokh , Rao Smita 
Published: July 2024

AbstractThis study assessed muscle activity (root mean square, RMS, and median frequency, MDF) to evaluate the acute response to blood flow restriction (BFR) resistance exercise (RE) and conventional moderate intensity (MI) RE. We also performed exploratory analyses of differences based on sex and exercise‐induced hypoalgesia (EIH). Fourteen asymptomatic individuals performed four sets of unilateral leg press with their dominant leg to volitional fatigue under two exercise conditions: BFR RE and MI RE. Dominant side rectus femoris (RF) and vastus lateralis (VL) muscle activity were measured using surface electromyography (sEMG) through exercise. RMS and MDF were calculated and compared between conditions and timepoints using a linear mixed model. Pressure pain thresholds (PPT) were tested before and immediately after exercise and used to quantify EIH. Participants were then divided into EIH responders and nonresponders, and the differences on RMS and MDF were compared between the two groups using Hedges' g. RMS significantly increased over time (RF: p = 0.0039; VL: p = 0.001) but not between conditions (RF: p = 0.4; VL: p = 0.67). MDF decreased over time (RF: p = 0.042; VL: p < 0.001) but not between conditions (RF: p = 0.74; VL: p = 0.77). Consistently lower muscle activation was found in females compared with males (BRF, RF: g = 0.63; VL, g = 0.5. MI, RF: g = 0.72; VL: g = 1.56), with more heterogeneous findings in MDF changes. For BFR, EIH responders showed greater RMS changes (Δ RMS) (RF: g = 0.90; VL: g = 1.21) but similar MDF changes (Δ MDF) (RF: g = 0.45; VL: g = 0.28) compared to nonresponders. For MI, EIH responders demonstrated greater increase on Δ RMS (g = 0.61) and decrease on Δ MDF (g = 0.68) in RF but similar changes in VL (Δ RMS: g = 0.40; Δ MDF: g = 0.39). These results indicate that when exercising to fatigue, no statistically significant difference was observed between BFR RE and conventional MI RE in Δ RMS and Δ MDF. Lower muscle activity was noticed in females. While exercising to volitional fatigue, muscle activity may contribute to EIH.
Alveolar hypoxia induces organ‐specific inflammasome‐related inflammation in male mouse lungs
Authors: Udjus Camilla , Halvorsen Bente , Kong Xiang Yi , Sagen Ellen Lund , Martinsen Marita , Yang Kuan , Løberg Else Marit , Christensen Geir , Skjønsberg Ole Henning , Larsen Karl‐Otto 
Published: July 2024

AbstractInflammation through activation of caspase‐1, seems to play a role in pulmonary hypertension induced by alveolar hypoxia. Whether alveolar hypoxia induces caspase‐1‐mediated inflammation and influx of leukocytes in other organs than the lungs, is not known. Our aim was to explore sites of caspase‐1‐related inflammation in alveolar hypoxia. Wild type (WT) mice were exposed to environmental hypoxia or room‐air, and organs were analyzed. Right heart catheterization was performed after 14 days of alveolar hypoxia in WT mice and mice transplanted with WT or caspase‐1−/− bone marrow. Hypoxia induced leukocyte accumulation and increased caspase‐1 protein in the lungs, not in other organs. WT mice transplanted with WT or caspase‐1−/− bone marrow showed no difference in pulmonary leukocyte accumulation or development of pulmonary hypertension after alveolar hypoxia. Caspase‐1 and IL‐18 were detected in bronchial epithelium in WT mice, and hypoxia induced IL‐18 secretion from bronchial epithelial cells. IL‐18 stimulation generated IL‐6 mRNA in monocytes. Phosphorylated STAT3 was increased in hypoxic lungs, not in other organs. Alveolar hypoxia induces caspase‐1 activation and leukocyte accumulation specific to the lungs, not in other organs. Caspase‐1 activation and IL‐18 secretion from bronchial epithelial cells might initiate hypoxia‐induced inflammation, leading to pulmonary hypertension.
Potential therapeutic properties of broccoli extract and soy isoflavones on improvement endometriosis and involved oxidative parameters
Authors: Sabetian Soudabeh , Archin Dialameh Parimah , Tanideh Nader , Gharesifard Behrooz , Ahmadi Moslem , Valibeigi Maryam , Kumar Perikala Vijayananda , Siahbani Sarah , Namavar Jahromi Bahia 
Published: July 2024

Abstract

Objectives
In Endometriosis is a gynecological disorder characterized by the growth of endometrial tissue outside the uterine cavity that is associated with chronic pelvic pain and subfertility. The purpose of the study was to investigate the effect of broccoli extract (BE) alone and in combination with soy isoflavones (SI) on endometrial implants in female rat.

Methods
In this study, endometriosis was induced surgically in 40 mature female rats. The rats were divided into 5 groups that were treated by oral gavage for 6 weeks with 0.5 mL of saline 0.9 %/day (control group), BE (3,000 mg/kg/day), SI (50 mg/kg/day), BE/soy isoflavones (BE 3000 mg/kg/day + soy isoflavones 50 mg/kg/day) and diphereline as a standard medication (3 mg/kg) intramuscularly. At the end of treatments, the volume and histopathology of the endometrial implants were compared among the 5 groups. The serum levels of oxidative parameters including superoxide dismutase (SOD), malondialdehyde (MDA) and tumor necrosis factor alpha (TNF-α) were also compared between the groups. The volume of the implants significantly decreased in diphereline group (p=0.002).

Results
The histopathological grade of endometrial implants in BE/SI and diphereline group were significantly decreased compared to the control group (p=0.001). The serum levels of SOD in BE group were enhanced significantly in comparison to the control group (p=0.034).

Conclusions
BE in combination with SI decreased the growth and histopathologic grades of transplanted endometrial implants. These herbal compounds may have the potential therapeutic effect to be used as an alternative medication for the treatment of endometriosis.
Empedokles in Nietzsches Dramenentwürfen
Authors: Audié Prudence 
Published: July 2024

Abstract

Empedocles in the Face of Mythological Deities. A Reading of Nietzsche’s Dramatic Drafts. This article examines Nietzsche’s interest in Empedocles. Less prominent in Nietzsche’s thought than other pre-Socratic philosophers, Empedocles is difficult to classify. He is characterized by his tensions and ambivalence. By examining Nietzsche’s various drafts for a drama about the death of the philosopher from Agrigento, I will show how philological studies combine with Nietzsche’s philosophical thinking to question Empedocles’ ambivalence toward mythological divinities. Art of staging, excessive desire for knowledge, expression of disgust with existence, recognition of the true measure of the living: the death of Empedocles is as ambiguous for Nietzsche as his conception of nature, torn between wonder, demystification and poetic fervor.
A magyarországi családi adó- és járulékkedvezmény kihasználhatósága az egyes jövedelmi tizedekben. Egy kísérlet a hazai családi kedvezmény újraelosztó hatásának megállapítására adatok szimulációjával
Authors: Varga Erzsébet Teréz 
Published: July 2024

A TANULMÁNY CÉLJA
A tanulmány kísérletet tesz arra, hogy meghatározza a hazai családi adó- és járulékkedvezmények kihasználhatóságát és újraelosztási hatását a különböző jövedelmi decilisekben. Az újszerűsége abban áll, hogy mindezt a háztartások szintjén végzi el az egyéni jövedelmek vizsgálata helyett.
ALKALMAZOTT MÓDSZERTAN
Az elemzéshez egy 4294 háztartást tartalmazó mintát generáltam, melyeknek összetétele és jövedelmi adatai a KSH által 2020-ra közölt arányuknak megfelel az egyes jövedelmi tizedekben. Miután kiszámoltam a minta minden háztartására a gyermekszám alapján elvileg igénybe vehető maximum kedvezményeket és a ténylegesen az adóköteles jövedelmükből igénybe vehető kedvezményeket, összehasonlítottam a decilisek eredményeit összességében, majd háztartási és adózói szinteken.
LEGFONTOSABB EREDMÉNYEK
Míg az alacsonyabb jövedelmi decilisekben az adóköteles jövedelem korlátozza az igénybevételt, mivel lényegesen alacsonyabb az aktív keresők aránya, a legmagasabb decilisekben a gyermekek száma jelent korlátot, arányuk a decilisen belül 8%-ot sem ért el. A legalacsonyabb jövedelmi decilisben az adókedvezményt igénybe vevők (aktív keresők) között több, mint kétszeres volt az igénybe vett átlagos kedvezmény a legfelső jövedelmi decilishez képest, és összességében a legalacsonyabb jövedelmi tizedeknek ötször annyi kedvezmény jutott, mint a legfelső tizedeknek, az egy háztartásra jutó átlagos kedvezmény pedig közel tízszeres a szegényebbek körében, tehát a decilisek közötti újraelosztási hatás az alacsonyabb jövedelműeknek kedvezett.
GAZDASÁGPOLITIKAI JAVASLATOK
Természetéből adódóan az adókedvezmény nem lehet képes javítani az adóköteles jövedelemmel nem rendelkezők helyzetén, így esetében csak az adózók közötti méltányosabb teherviselést vizsgálhatjuk. Az adózó gyermekes családok között legnehezebb helyzetben az egyszülős családok vannak, náluk a legmagasabb a szegénységi kockázat, mivel csak a gondozó szülő tudja igénybe venni a kedvezményt. Ahogy a legutóbbi népszámlálási adatok is rámutattak, az elváltak aránya viszont növekszik Magyarországon. Az ő helyzetükön javítana, ha a gondozó szülő alacsony jövedelme miatt nem igénybe vehető kedvezményt a különélő szülő személyi jövedelméből érvényesíthetné, legalább a megfizetett tartásdíj erejéig (akár közvetlenül a gyermekhez, illetve az őt gondozó szülőhöz visszatérítve). Ezzel megszüntethető lenne az elvált szülők gyermekeit érintő most fennálló negatív diszkrimináció a családi adókedvezményben.
A IMPORTÂNCIA DA ARGUMENTAÇÃO NO DISCURSO POLÍTICO: COMO OS CANDIDATOS À PREFEITURA DO RIO DE JANEIRO INFLUENCIARAM SEUS ELEITORES?
Authors: Alves Verônica Passos , Araújo Bianca Brito de Carvalho 
Published: July 2024

A comunicação é a base da interação social e, no campo político, ela é um elemento fundamental. Usar a linguagem de maneira eficaz na construção de uma argumentação que influencie a tomada de decisões dos eleitores em potencial é uma das características indispensáveis para quem faz política. Compreendendo que a política se desenvolve a partir do embate de ideias, os objetivos deste trabalho são apresentar os conceitos do artigo “A argumentação em uma problemática da influência” (CHARAUDEAU, 2016) e propor uma análise destes conceitos em dois corpus retirados de contextos de campanha política em que os candidatos à prefeitura Eduardo Paes e Marcelo Crivella apresentam suas ideias ligadas à postura de um bom gestor para a cidade do Rio de Janeiro. Essa análise nos leva a compreender a importância da argumentação no discurso político e sua influência no resultado eleitoral.
Ortografía en el discurso oral: enseñar lengua según Cassany, Luna y Sanz
Authors: Ramírez Diana Patricia , Mendoza Rodríguez Jeison Orlando 
Published: July 2024

El objetivo de este artículo es presentar el análisis de la incidencia de la ortografía en el discurso oral en discentes de séptimo grado. El marco de inteligibilidad es la teoría Enseñar Lengua de Cassany, Luna y Sanz, cuya metodología se estableció por medio del enfoque cualitativo y método de Investigación-Acción. La recolección de información se efectuó a través de una prueba de entrada, entrevista a docentes, diario de campo, propuesta pedagógica y prueba de salida. Una vez aplicada la propuesta y los demás instrumentos se determinó la relevancia que tiene la aplicación de la ortografía. También, la lúdica y la innovación fueron fundamentales para superar las dificultades y mantener la motivación por la lengua y el lenguaje con diversas estrategias: letra-sonido, técnica del 1+1, juegos lingüísticos y de rol se logró mejorar el desempeño académico y se consolidó como una herramienta útil para la corrección comunicativa.
Júlia Hajdu (1925–1987) – Career of a woman operetta composer
Authors: Lengyel Emese 
Published: July 2024

AbstractThe object of this presentation is Júlia Hajdu (1925–1987), the first and only female Hungarian operetta composer. Although there is no abundance of female composers in either international or Hungarian music literature, most of the few were canonically mistreated, despite their creations being worthy of research. The author of choice, Júlia Hajdu, had a rather rich artistic career during which she excelled in various musical genres, such as the composition of dance songs, operettas, revues, dance suites, and incidental music. Besides composing, she was also an outstanding pianist. At the Zeneakadémia (Liszt Ferenc Academy of Music), her master teachers were Zoltán Kodály (1882–1967) and György Ránki (1907–1992) – the latter, too, being a composer of operettas. Hajdu studied folk music from Kodály and jazz orchestration from Ránki. Hajdu's name was soon mentioned next to the best-known creators of popular genres by both her contemporaries and the critics of the age. Among others, she worked on the popular music shows of Magyar Televízió (Hungarian Television) and was employed as Hanna Honthy's piano accompanist. Hajdu recorded hundreds of dance songs, revues, and dance suites, as well as fourteen operettas, including those for radio and television broadcasts. Her career is to be explored within the cultural, political, and civilizational contexts of state socialism, thus understanding her work as not only another oeuvre of an operetta composer, but also as a representation of the artistic sentiment of a whole era. During her active years, she had to make compromises which she later interpreted as assertions of herself as a female artist in a male-dominated cultural milieu. After recognizing various narrative patterns in her creations, I aim to discuss Hajdu's career along two of the most prevalent and recurring issues: the “female composer as a sensation” narrative, and the “significance of the master teacher” narrative.
Review of <em>Ethical Crossroads in Literary Modernism</em> (2023), edited by Katherine Ebury, Bridget English, and Matthew Fogarty
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Authors: Wagner Hadas 
Published: July 2024

Ethical Crossroads in Literary Modernism, edited by Katherine Ebury, Bridget English, and Matthew Fogarty, builds on new modernist studies and recent criticism to interrogate the term 'modernist ethics.' The collection stands out in the breadth of its scope, seeking to act as a definitive guide to those seeking to familiarize themselves with the multifaceted conjunction of modernism and ethics. While other book-length studies in the field tend to focus either on a specific canonical writer, or on narrower aspects of ethics, Ethical Crossroads is broadly divided into four methodological sections: 'The Ethics of Mind and Body,' 'Planetary Ethics,' 'Legal Ethics,' and 'Intersectional Ethics.' Each of these sections includes a wide range of theories and approaches, which are discussed in relation to both canonical and non-canonical texts. In combining such an expansive approach together with attention to the different localities, specificities and nuances making up literary modernism, Ethical Crossroads emerges as a rich and thought-provoking collection, and a welcome contribution to scholarship.
Percepción de los estudiantes universitarios sobre el uso de Bitcoin como medio de pago en El Salvador
Authors: Zapata Kriscia Vanessa , Flores-Bonilla Jenny Elizabeth , Coreas-Flores Edwin Osmil 
Published: July 2024

En El Salvador, las criptomonedas, especialmente el Bitcoin, han ganado notoriedad, marcando un hito el 9 de junio de 2021, cuando la Asamblea Legislativa aprobó a través del Decreto N° 57 la Ley Bitcoin. Esta nueva Ley posiciona al Bitcoin como moneda de curso legal, convirtiendo a El Salvador en el primer país en el mundo en tomar tal medida. Esta investigación tiene como objetivo describir la percepción de estudiantes universitarios hacia el uso Bitcoin como medio de pago. La muestra es de362 estudiantes de diez universidades de El Salvador. El instrumento diseñado evalúa variables como experiencia, disposición y uso del Bitcoin, proporcionando datos significativos para comprender los desafíos y oportunidades percibidos por los estudiantes. Según los estudiantes universitarios, los principales desafíos para utilizar Bitcoin como medio de pago son la interconectividad digital y la educación financiera. Un análisis de correspondencia entre las variables interconectividad digital y la disposición de uso de Bitcoin confirma que la primera es un factor determinante para la disposición de utilizar Bitcoin en transacciones financieras.
Relación entre las estructuras de capital de trabajo y la rentabilidad de pequeñas y medianas empresas del sector construcción de Colombia
Authors: López-Díaz Víctor Hugo , Gómez-Chaves Miguel Ángel , Patiño-Folleco María Camila , Padilla-Ortiz Verónica 
Published: July 2024

Como en la mayoría de economías, las pequeñas y medianas empresas en Colombia enfrentan grandes dificultades de financiación y liquidez debido a un bajo conocimiento respecto a la gestión del capital de trabajo. El presente documento se orienta hacia el análisis existente de las estructuras de capital de trabajo y la rentabilidad de las pymes del sector construcción de Colombia entre los años 2016 – 2020. La metodología parte del paradigma cuantitativo, por cuanto se analiza el comportamiento de variables como, inventario, cuentas por cobrar, efectivo, entre otras; con enfoque empírico-analítico, basado en la experiencia financiera de las pymes del sector construcción, además, el método fue deductivo con un tipo de investigación correlacional. Se toma como población objeto de estudio los estados financieros que proporcionaron 11.035 pymes del sector construcción ante la Superintendencia de Sociedades durante los años 2016 – 2020. Como resultado se evidencia que no existe una estabilidad en cuanto a la relación entre las estructuras de capital de trabajo frente a los márgenes de rentabilidad de las pymes del sector construcción, dado que, de los seis capitales de trabajo analizados, tres de ellos, el bruto, operativo y neto presentan un coeficiente de correlación significativamente positivo frente a los indicadores margen antes de impuestos y margen neto, de los siete indicadores de rentabilidad analizados. Dado el comportamiento histórico de estas variables, cuando se percibe una variación de uno de los factores, el otro fluctúa en el mismo sentido, indicando que, a una mayor eficiencia en la gestión del capital de trabajo bruto, operativo y neto influye positivamente en los resultados empresariales de estas empresas del sector construcción.
HITCH DEVICE MODERNIZATION FOR TRANSLOADING OF BALE CARGO
Authors: Kozar Leonid , Romanovych Yevhenii , Kravets Andrii , Babenko Andrii 
Published: July 2024

The operation of unloading bales from a covered railway wagon is one of the most labor-intensive and dangerous operations when transporting bale cargo. The article proposes a modernized outside-mounted load-handling device for a universal light-sized forklift. The device is a mechanical equipment for transloading of bale cargo. The device includes a push-pull attachment (a purchased part) on which a frame, a lever clamp and a hydraulic cylinder are mounted. Тtrolleys are installed on the forks of the loader. The trolley is equipped with a roller in the front part and a frame in the back part for longitudinal movement on the forks. The trolley also has a support for the movable pusher plate and a grip for lifting the front edge of the bale. The trolleys are connected to the stationary pusher plate by a lever-type limiter. Before the start of gripping, the forklift is tilted forward at an angle from 3 to 5°, the trolleys are in the most forward position and are supported by a pusher. In this case, the rollers are in the position where they have moved off the forks. By moving the forklift forward, the trolley grips are inserted under the bale. The pusher is brought into the folded state. The loader moves forward, the noses of the forks abut against the roller and it rolls onto the forks, lifting the front edge of the bale. The forks are fully inserted under the bale. The clamp comes into operation, holding the load on the forks. This allows the bales to be removed from the stack and transported. The trolley was designed using CAD KOMPAS-3D. The proposed device is capable of picking up bales stacked without gaps and can be used inside a covered railway wagon. Commonly used side-clamp devices are not capable of this. The mathematical relation of the required traction force of the loader on the geometric parameters of the trolley is derived. It has been established that the required traction force is 60 to 70 % of the maximum traction force achieved by light-sized forklifts with a lifting capacity of 1000 kg.
METHODOLOGY AND EXAMPLE OF CALCULATING THE RATIONAL RESOURCE OF AXIAL-PISTON HYDRAULIC MACHINES OF MOBILE EQUIPMENT
Authors: Voronin Serhii , Stefanov Volodymyr , Vasianovych Roman , Tryfonov Taras , Pivovarov Sergii 
Published: July 2024

The article analyzes approaches for creating models for optimizing the durability of mobile machine units. On the basis of the selected model, in which the target function is the total specific costs of purchasing the machine and the costs of maintaining its working condition, a method of calculating the rational resource of axial-plunger hydraulic machines has been developed for the condition when the resource of the hydraulic machine is limited by the resource of only its plunger pairs. The methodology, built on the basis of the chosen model for optimizing the durability of simple technical systems, takes into account the patterns of wear of plunger pairs under certain operating conditions, and also takes into account the proposed dependencies for calculating their total wear limit. The methodology consists of five consecutive operations, namely: determining the total marginal wear; obtaining experimental patterns of wear of plunger pairs over time in the form of regression equations; calculation of the number and periodicity of technical maintenance of the hydraulic machine for the inter-repair cycle; calculation of the rational resource of the hydraulic machine.The results of the comparative calculation of the rational resource of the adjustable axial-plunger pump 321.224 of the hydraulic system of the single-bucket excavator EO-3323 according to the developed method are also given.The total marginal wear of the pump was determined according to the criterion of reducing its efficiency, namely from the condition of a drop due to the wear of its volume coefficient of useful action by 30 %.To obtain the patterns of wear of the pump's plunger pairs, the results of previous operational tests of the pump were used for two variants of its lubrication: lubrication with ordinary hydraulic oil and lubrication with oil whose anti-wear properties are activated by an external electric field.
Specific costs for the purchase of the pump, which are included in the durability optimization model in the form of depreciation deductions, were calculated for the inter-repair cycle. The specific costs of maintaining the working condition of the pump were equal to the costs of its maintenance, during which hydraulic oil and filters are replaced, that is, the pattern of wear of plunger pairs is returned to the starting point.