bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ріст лісових культур сосни та дуба, створених різними видами садивного матеріалу, у Правобережному Лісостепу України
Authors: Василевський О. Г. , Єлісавенко Ю. А. , Тарнопільський П. Б. , Румянцев М. Г. 
Published: August 2024

Наведено показники росту одно- і чотирирічних лісових культур дуба звичайного (Quercus robur L.) і сосни звичайної (Pinus sylvestris L.), створених різними видами садивного матеріалу. Дослідження проведено у лісовому фонді філій «Вінницьке ЛГ» (Вінницька область) та «Славутське ЛГ» (Хмельницька область) державного спеціалізованого господарського підприємства «Ліси України» (Подільський лісовий офіс). Виявлено, що одно- і чотирирічні лісові культури дуба звичайного і сосни звичайної, створені сіянцями із закритою кореневою системою, характеризувалися вищими висотою (на 6–18 %), приростом за висотою (на 7–34 %) та діаметром кореневої шийки (на 21–39 %), а також приживлюваністю (85–93 % проти 71 % для однорічних культур дуба та 93 % проти 86 % для однорічних культур сосни), порівнюючи з культурами, створеними сіянцями із відкритою кореневою системою. Результати досліджень доцільно використати під час розроблення рекомендацій щодо удосконалення технології створення лісових культур в умовах Правобережного Лісостепу України.
Підстилка як маркер антропотехногенних змін у соснових лісах рівнинної частини України
Authors: Ворон В. П. , Коваль І. М. 
Published: August 2024

Виявлено особливості трансформації ланки «опад – підстилка» соснових лісостанів в умовах антропотехногенного забруднення та рекреації. Запас і структура лісової підстилки залежать від типу лісорослинних умов і віку насаджень. Через порушення екологічних умов уповільнюються процеси мінералізації фітодетриту. Унаслідок цього накопичується мортмаса, що відбивається на запасах, потужності та структурі підстилки. Так, у техногенній зоні період формування лісової підстилки збільшується на 0,9–3,0 року, а вміст важких металів у ній – у 3,4–5,5 разу, ніж за межами цієї зони. У міру збільшення рівня рекреаційного навантаження зменшується запас підстилки, а тривалість існування мортмаси в усіх підгоризонтах подовжується (різниця між сосняками першої та четвертої стадій рекреаційної дигресії становить один рік). Одержані дані свідчить про доцільність використання показників запасу, потужності та структури підстилки для індикації інтенсивності антропотехногенного впливу.
TINJAUAN KONSENTRASI HAMBATAN MINIMUM BEBERAPA TANAMAN TERHADAP Mycobacterium tuberculosis
Authors: Srivaliana Hilda , Viosepta Prasetya Ahmada , Keasa Maura Geasynova Aktha , Angelina Sitorus Joy , Nadira Putri Meira , Latifah Rahma Naila , Caroline Affandy Rosa , Sabila Salsa , Fitria Gunawan Sarah Nur , Habibah Siri 
Published: August 2024

ABSTRAK

TBC adalah penyakit yang menjadi perhatian khusus global. Pada umumnya infeksi TB diobati dengan antibiotik seperti rifampisin, isoniazid, etambutol, streptomisin, dan pirazinamid. Namun, tingginya angka penyakit TBC di Indonesia dan dunia berbanding lurus dengan tingginya tingkat resistensi terhadap obat TBC yang dikenal dengan multidrug-resistant tuberculosis (MDR TB) sehingga diperlukan penemuan obat baru anti-tuberkulosis. Obat dari bahan alam dapat menjadi alternatif untuk pengobatan TB. Aktivitas tumbuhan sebagai anti-TB dapat diketahui dengan melihat nilai MIC (Minimum Inhibitory Concentration). Terdapat 13 tanaman yang diidentifikasi memiliki aktivitas anti TB yang diklasifikasikan berdasarkan nilai MIC. Didapatkan hasil 5 tanaman termasuk dalam kategori MIC yang sangat aktif, 7 aktif, dan 1 sedang.

Kata Kunci: Tuberkulosis, Mycrobacterium Tuberculosis, MIC
Experiences of Indonesian women with breast cancer underwent treatment decision-making: A qualitative study
Authors: Sitanggang Yenni Ferawati , Lin Hung-Ru 
Published: August 2024

Background: Patients with breast cancer face a complex situation upon receiving their diagnosis and considering future treatment options. In Indonesian culture, relatives and others significantly influence decision-making processes. Understanding the perspectives of Indonesian women with breast cancer regarding treatment decision-making can enhance satisfaction with the care provided.
Objective: This study aimed to explore the experiences of Indonesian women with breast cancer regarding treatment decision-making.
Methods: A qualitative descriptive study design was utilized. Purposive sampling was employed to select the study participants. In-depth interviews were conducted with 15 women with breast cancer between March and June 2023. The data were analyzed using thematic analysis.
Results: Three main themes were developed: 1) Emotional impact and uncertainty in cancer care, 2) Clear communication and support for patients, and 3) Family-centered decision-making in treatment planning.
Conclusion: This study highlights the perspectives of Indonesian women with breast cancer on treatment decision-making. Nurses play a crucial role in providing clear information to patients and their families during the decision-making process. Understanding the experiences of women with breast cancer can help support and empower patients through effective communication while they undergo treatment.
Adherence to treatment in pulmonary tuberculosis: Rodgers’ evolutionary concept analysis
Authors: Prasetyo Yunus Adhy , Thanasilp Sureeporn , Preechawong Sunida 
Published: August 2024

Background: Adherence to treatment is essential for the management of pulmonary tuberculosis. Nurses and healthcare professionals play a significant role in promoting adherence behavior among this population. Nevertheless, defining adherence to treatment within this particular population remains complex.
Objective: This study aimed to explore and clarify the concept of adherence to treatment among individuals with pulmonary tuberculosis.
Methods: Rodgers’ evolutionary concept analysis was employed in this study. A literature search was conducted in the PubMed and Scopus databases to identify relevant studies published between July 2013 and July 2023.
Results: The attributes of adherence to treatment in pulmonary tuberculosis consist of multiple components: biological, individual, social, health service, and policy-making processes. Antecedents include various patient-related factors as well as factors associated with clinical conditions and patient-health professional engagement. Three consequences of the concept have emerged: enhanced treatment efficacy, increased commitment to tuberculosis treatment adherence, and improved health service quality.
Conclusion: This study provides a comprehensive operational definition of adherence to tuberculosis treatment, including its attributes, antecedents, and consequences. This framework will assist nurses in evaluating adherence more effectively. However, further research into the experiences of individuals adhering to tuberculosis treatment is needed to confirm and enhance these strategies.
TARIKAN PERJALANAN WISATAWAN DI EMPAT GEOSITE PADA KAWASAN GEOPARK BAYAH DOME KABUPATEN LEBAK TAHUN 2030
Authors: NURDIYATMI HUDA EKA , DJAKAPERMANA RUCHAT DENI , ARTININGSIH TITIK PENTA 
Published: August 2024

Potensi wisata di Kabupaten Lebak sangatlah beragam dan masih banyak potensi yang bisa dikembangkan. Salah satunya adalah Kawasan Geopark Bayah Dome yang memiliki 32 geosite yang tersebar di 10 kecamatan. Dari 32 geosite yang ada empat diantaranya berpotensi untuk dikunjungi wisatawan dan memiliki nilai geologi, nilai budaya dan nilai keberlanjutan tinggi. Adapun goesite yang memiliki nilai-nilai tersebut adalah Pantai Tanjung Layar, Pantai Karangbokor, Gunung Luhur dan Curug Ciporolak. Tentunya jika ingin mengembangkan sektor pariwisata ini dibutuhkan sektor pendukung agar bisa bersinergi, yaitu sektor transportasi. Penyediaan transportasi yang ada saat ini Kabupaten Lebak belum bisa menjangkau keempat geosite ini secara efektif dan efesien. Untuk menyediakan sistem transportasi tersebut, maka dibutuhkan jumlah tarikan wisatawan yang direncanakan untuk jangka waktu menengah. Oleh karena itu penulisan jurnal ini bertujuan untuk menganalisis besaran intesitas trip attraction atau tarikan perjalanan wisatawan pada Pantai Tanjung Layar, Pantai Karangbokor, Gunung Luhur dan Curug Ciporolak. Model yang digunakan dalam penelitian ini model potensi gravitasi dengan menggunakan Drew’s technique. Hasil penelitian ini adalah daya tarik perjalanan tertinggi yaitu di Tanjung Layar–Karang Bokor adalah 321.390.119 perjalanan orang atau 46, 06% pada tahun 2030, Kata Kunci: Transportasi, Tarikan Perjalanan Wisatawan ABSTRACT The tourism potential in Lebak Regency is very diverse and there is still a lot of potential that can be developed. One of them is the Bayah Dome Geopark Area, which has 32 sites spread over 10 districts. Of the 32 sites, four of them have the potential to be visited by tourists and have high geological, cultural, and sustainability values. The sites that have these values are Tanjung Layar Beach, Karangbokor Beach, Mount Luhur, and Ciporolak Waterfall. Of course, if you want to develop the tourism sector, a supporting needed sector that it can synergize, with namely the transportation sector. The current transportation provision for Lebak Regency has not been able to reach these four geosites effectively and efficiently. To provide this transportation system, it is necessary to attract several tourists planned for the medium term. Therefore writing this journal aims to analyze the magnitude of the intensity of the trip attraction or the attraction of tourist trips at Tanjung Layar Beach, Karangbokor Beach, Mount Luhur, and Ciporolak Waterfall. The model used in this study is the gravitational potential model using Drew’s Technique. The results of this study are that the highest travel attraction is in Tanjung Layar–Karang Bokor with 321,390,119 trips or 46.06% in 2030. Keywords: Transportation, Attraction of Tourist Travels
Model Matematika SEIR Pada Penyakit Diabetes Mellitus Tipe 2
Authors: Nurazizah Siti , Sani Asrul , Kabil Djafar Muhammad , Somayasa Wayan , La Gubu  
Published: August 2024

Diabetes mellitus adalah penyakit metabolisme karbohidrat, protein dan lemak yang tidak normal. Penyakit ini disebabkan oleh kurangnya sensitivitas otot dan jaringan terhadap insulin, yang disebut resistensi insulin, atau kekurangan hormon insulin. Diabetes mellitus tipe 2, pankreas masih dapat membuat insulin, tetapi insulin tersebut berkualitas buruk dan tidak dapat berfungsi dengan baik. Penelitian ini bertujuan untuk membahas model epidemik untuk penyakit diabetes mellitus tipe 2. Dari hasil analisis model diperoleh dua titik kesetimbangan yaitu titik kesetimbangan bebas penyakit dan titik kesetimbangan endemik. Analisis kestabilan titik kesetimbangan bebas penyakit menggunakan linearisasi disekitar titik kesetimbangan. Untuk mencari bilangan reproduksi dasar juga dilakukan dengan metode matriks generasi selanjutnya. Hasilnya, titik kesetimbangan bebas penyakit stabil asimtotik jika bilangan reproduksi dasar kurang dari satu, artinya penyakit akan menghilang setelah jangka waktu tertentu, sedangkan titik kesetimbangan endemik stabil jika bilangan reproduksi dasar lebih dari satu, artinya penyakit akan tetap ada. Simulasi numerik model untuk penyakit diabetes mellitus tipe 2 yang dilakukan sejalan dengan analisis perilaku model.
UJI GOODNESS OF FIT UNTUK DISTRIBUSI GEOMETRIK MENGGUNAKAN UJI STATISTIK KOLMOGOROV-SMIRNOV
Authors: Amelia Reski , Somayasa Wayan , Alfian  , Ruslan  
Published: August 2024

Penelitian ini bertujuan untuk mengevaluasi kecocokan distribusi geometrik dengan data lemparan bola basket. Estimasi parameter ( ) distribusi geometrik dengan metode MLE diperoleh dengan persamaan . Ketakbiasan penduga MLE diuji dengan membandingakn nilai variansi dan nilai BBCR, diperoleh nilai var sehingga bukan merupakn UMVUE. Hasil analisis statistik menggunakan uji Kolmogorov-Smirnov menunjukkan bahwa data tersebut mengikuti distribusi geometrik dengan parameter ​ . Statistik uji Kolmogorov-Smirnov = 4,0135 lebih besar dari nilai tabel kuantil-kuantil = 0,3667 pada tingkat signifikansi α = 0,05 untuk n = 25. Oleh karena itu, hipotesis nol yang menyatakan bahwa data mengikuti distribusi geometrik diterima, menunjukkan kesesuaian yang signifikan antara distribusi geometrik yang diasumsikan dan distribusi sebenarnya dari data lemparan bola basket.
Innovative nomogram for predicting 1-year clinically driven revascularization outcomes in endovascular femoropopliteal disease
Authors: Pan Dikang , Wu Sensen , Wang Hui , Ning Yachan , Guo Jianming , Wang Cong , Guo Lianrui , Sang Hongfei , Gu Yongquan 
Published: August 2024

PurposeFemoropopliteal artery disease (FPAD) is a common vascular disease that usually requires surgical treatment. The aim of this study was to apply predictive modeling to develop predictive models for predicting clinically driven target revascularization (CD-TLR) events 1 year after intervention in patients with FPAD.Materials and methodsIn this study, clinical data were collected from a total of 484 patients who underwent FPAD endovascular intervention from 2014 to 2019. According to the inclusion and exclusion criteria, 400 patients will be finally included and assigned to the training cohort and test cohort in the ratio of 7:3. By analyzing these data through statistical methods, we will explore the effects of different factors on target revascularization events 1 year after intervention in FPAD patients, and build the corresponding prediction model of the column line graph.ResultsThe final nomogram model consisted of 5 independent predictors: history of cerebrovascular disease, lesion length &gt;15 cm, no atherectomy device used, no medicated balloon used and procedure time. The C-index of the model was 0.766 and 0.726 for the training cohort and validation cohort, respectively. The calibration curves also showed that the model had satisfactory agreement in both cohorts.ConclusionsThe newly developed prediction model can accurately predict clinically driven target revascularization events at 1 year in patients with FPAD, providing valuable information for the development of individualized treatment plans.
Prediction of hydrogen consumption scale and hydrogen price based on LEAP model and two-factor learning curve
Authors: Li Hongxia , Yu Haiguo , Wang Haiting , Gou Xiaokan , Liu Fei , Li Lixin , Wang Qian , Zhang Xin , Li Yuanyuan 
Published: August 2024

Under the dual-carbon target, hydrogen energy, as a zero-carbon secondary energy source, has great scope for replacing fossil feedstocks in the fields of energy, transportation and industry. However, the current research on the competitiveness of hydrogen energy in various fields is not sufficiently addressed. In this paper, we use the LEAP model to predict the future scale of hydrogen use and the two-factor learning curve to predict the trend of hydrogen price change from 2025 to 2050, using Qinghai Province as the research background. At the same time, considering the carbon emission reduction benefits and raw material costs, the competitiveness of hydrogen energy in energy, transportation, industry and other fields in the future is compared. The results show that: 1) The hydrogen load scale in Qinghai Province will grow fast from 2025 to 2030. From 2030 to 2040, it slows under the steady and basic scenarios but remains high under the accelerated one. By 2040, the consumption scales are 1.057 million, 649,000 and 442,000 tons respectively. 2) The price of hydrogen energy will drop rapidly from the current 28 CNY/kg to about 20 CNY/kg in the next 5 years. By 2040, the price of hydrogen energy will be reduced to about 17 CNY/kg. 3) In terms of hydrogen energy competitiveness, when carbon emissions are not taken into account, hydrogen energy is currently competitive in the transportation field. During 2032–2038, it will be competitive in the field of methanol synthesis. By 2040, hydrogen energy will not be competitive in the fields of ammonia synthesis and power/heating. When considering carbon emissions, the competitiveness of hydrogen energy in the transportation field will become greater. The competitive year in the field of methanol synthesis will be 1–2 years ahead. By 2040, it will not be competitive in the field of synthetic ammonia and power/heating, but the gap will be significantly reduced due to the consideration of carbon emissions.
Effect of different single and combined antihypertensive drug regimens on the mortality of critical care patients
Authors: Fang Yipeng , Huang Xianxi , Shi Junyu , Ren Chunhong , Zhang Xin 
Published: August 2024

ObjectiveTo investigate the effect of different single and combined pre-admission antihypertensive drug regimens on the prognosis of critically ill patients.MethodsWe performed a retrospective cohort study using data from the Medical Information Mart for Intensive Care-IV (MIMIC-IV) database. All initial ICU admission records of patients with hypertension and previous antihypertensive exposure before ICU admission were included. Our primary outcome was 90-day mortality. Propensity score matching (PSM) and inverse probability of treatment weighting (IPTW) were used to balance the distribution of baseline characteristics. Logistic regression analysis and subgroup analysis were performed to determine the independent effect of different single and combined antihypertensive drug regimens on 90-day mortality.ResultsA total of 13,142 patients were included in the final analysis. The 90-day mortality rate in the combined groups is lower than that in the single therapy group (10.94% vs 11.12%), but no statistical significance was found in the original cohort (p = 0.742). After adjustment for potential confounders, the significantly decreased 90-day mortality rate was found in the combined groups (10.78% vs 12.65%, p = 0.004 in PSM; 10.34% vs 11.90%, p = 0.007). Patients who were exposed to either ACEIs or ARBs had a better prognosis than those not exposed (7.19% vs 17.08%, p &lt; 0.001 in single antihypertensive groups; 8.14% vs18.91%, p &lt; 0.001 in combined antihypertensive groups). The results keep robustness in the PSM and IPTW cohorts. In the logistic regression model analysis, combined therapy was associated with a 12%–20% reduced risk of 90-day death after adjusting potential confounders (OR 0.80–0.88, all p &lt; 0.05), while exposure to ACEIs or ARBs was associated with the decreased risk of 90-day death by 52%–62% (OR 0.38–0.48, all p &lt; 0.001) and 40%–62% (OR 0.38–0.60, all p &lt; 0.001) in the single and combined therapy groups, respectively. The results were still robust to subgroup analysis.ConclusionsPre-admission combined antihypertensive therapy is associated with a significantly lower risk of death than exposure to single antihypertensives in critically ill patients. Meanwhile, either ACEIs or ARBs seem to be the optimal candidates for both single and combined therapy. Further high-quality trials are needed to confirm our findings.
Comparison of lidocaine bicarbonate with fentanyl and chloroprocaine for epidural anesthesia during cesarean section: a randomized, controlled, double-blind clinical trial
Authors: Yu Jing , Liu Jingjing , Wang Chenran , Song Congzhong , He Gangming , Liu Chaohui , Mei Zhong , Huang Shaoqiang 
Published: August 2024

Chloroprocaine and lidocaine bicarbonate are commonly used for epidural anesthesia because of their rapid onset, particularly in the case of conversion from epidural labor analgesia to emergency cesarean section. However, it is unclear whether lidocaine bicarbonate combined with fentanyl has an advantage over chloroprocaine alone in emergency cesarean section. In this study, 102 women who underwent elective cesarean section received 15 mL 3% chloroprocaine and 1 mL saline (CP group) or 15 mL 1.73% lidocaine bicarbonate and 1 mL fentanyl 50 μg (LF group) for epidural anesthesia. Nociceptive block level was assessed by pinprick and recorded every minute. The primary outcome was the onset time to T6 block. The median onset time to T6 analgesia was 10 [10, 10] min in the CP group and 10 [7, 10] min in the LF group (COX model for CP versus LF, HR 0.47, 95% CI 0.23–0.95, p = 0.035). The median onset time to T8 analgesia was 7 [5, 9] min in CP group and 5 [4, 7] min in LF group (COX model for CP versus LF, HR 0.61, 95% CI 0.39–0.95, p = 0.027). The proportion of hypotension episodes occurring before delivery in LF group was lower than that in CP group (p = 0.011). The incidence of block level ≥ T4 after supplemental dosing in the LF group was lower than that in the CP group (p = 0.031). Compared with 3% chloroprocaine, 1.73% lidocaine bicarbonate combined with fentanyl 50 μg has a slightly faster onset time and less hypotension in epidural anesthesia for cesarean section.Clinical Trial Registration:http://www.chictr.org.cn/index.html, identifier ChiCTR2200056180.
Sedative and anxiolytic effects of Capparis sicula Duhamel: in vivo and in silico approaches with phytochemical profiling
Authors: Karpuz Ağören Büşra , Küpeli Akkol Esra , Çelik Ismail , Sobarzo-Sánchez Eduardo 
Published: August 2024

The World Health Organization reports that 30% of adults worldwide suffer from insomnia, while 10% of people worldwide suffer with various forms of anxiety. The significant negative effects of conventional medications used to treat anxiety and insomnia, such as abuse, addiction, amnesia, and cognitive and sexual dysfunction, have led to an increased preference for naturally derived substances with fewer side effects. Accordingly, in this study, the sedative and anxiolytic effects of n-hexane, ethyl acetate (EtOAc), methanol (MeOH) and water extracts of the aerial parts of Capparis sicula Duhamel., which is used for sedative purposes in folk medicine, were evaluated. To evaluate the sedative and anxiolytic effects of each extract, bioassay systems were used including traction and hole-board tests. The MeOH extract of C. sicula was the most active extract on in vivo traction and hole-board tests compared to Diazepam. From the MeOH extract, major components were isolated, and their structures were identified as three flavonoid glycosides [rutin (1), quercetin-3-O-glucoside (2), and quercetin 3-O-rhamnoside (3)] using spectral techniques. The most abundant component was determined to be rutin, comprising 8 mg/100 mg dry extract in MeOH extract and 76.7 mg/100 mg dry fraction in fraction C using HPLC. The molecular docking studies evaluated the interaction of isolated flavonoid glycosides with the interaction energies and protein-ligand interaction details of the anxiety-related receptors GABAA and GABAB. For the GABAA receptor, quercetin-3-O-glucoside demonstrated the highest docking score. Quercetin-3-O-rhamnoside and rutin also show promising interactions, particularly with the GABAB receptor, highlighting their potential as modulators of these receptors. In conclusion, the use of C. sicula for sedative purposes in folk medicine has been confirmed for the first time by in vivo studies, and its possible active compounds and sedative-anxiolytic mechanism have been determined through phytochemical and in silico studies.