bluuebunny/crossref_metadata_2025_split huggingface dataset:
Transcatheter closure of atrial septal defects in children and adolescents: Single‐center experience with the GORE® septal occluder
Authors: Grohmann J. , Höhn R. , Fleck T. , Schmoor C. , Stiller B. 
Published: March 2014

ObjectivesDevice closure of atrial septal defects (ASD II) is an alternative to surgery. ASD morphology and intracardiac relationships may influence device selection. Biocompatibility, techniques for closing large or multiple defects, and the risk of erosion are main issues in childrenBackgroundThe GORE® Septal Occluder (GSO) is a non‐self‐centering device with a flat and conformable nitinol‐frame covered with expanded polytetrafluoroethylene. We hereby evaluate our initial experience in children to demonstrate feasibility, efficacy, and safety. Methods: Single‐center retrospective intention‐to‐treat analysis of GSO procedures in children and adolescents with hemodynamically significant ASD. All procedures were conducted under general anesthesia, fluoroscopy and transesophageal echocardiography. All defects were sized using stop‐flow‐technique. GSOs of 20–30 mm disc‐diameter were implanted.ResultsGSO implantation was attempted in 45 with technical success in 41 patients, median age 6 (range 3–17) years, bodyweight 19 (12–95) kg. Median balloon‐sized diameter was 13 (8–19) mm resulting in a GSO‐to‐ASD‐ratio of 2 (1.7–2.5). Deficient retro‐aortic rims (<3 mm) were found in 12 patients, and 10 of these 12 defects could be closed. We observed no complications. Four extensive or multiple ASDs were not treated successfully with GSO. After retrieval, one was closed with a different device; three patients needed surgical therapy. The median follow‐up of four (range 0.2–22) months was uneventful in all patientsConclusionsWe found the GSO device closure of ASDs in children to be effective. However, our initial experience is limited to short‐ and mid‐term‐follow‐up of a low number of patients. © 2014 Wiley Periodicals, Inc.
Impact of bifurcation stent technique on clinical outcomes in patients with a medina 0,0,1 coronary bifurcation lesion: Results from the COBIS (COronary BIfurcation Stenting) II registry
Authors: Jang Woo Jin , Song Young Bin , Hahn Joo‐Yong , Choi Seung‐Hyuk , Kim Hyo‐Soo , Yu Cheol Woong , Rha Seung Woon , Jang Yangsoo , Seung Ki Bae , Gwon Hyeon‐Cheol 
Published: March 2014

ObjectiveTo compare the long‐term clinical outcomes of patients treated with 1‐ versus 2‐stent techniques for Medina 0,0,1 type bifurcation lesions. Background: Little is known about clinical outcomes and optimal treatment strategies for Medina 0,0,1 type bifurcation lesionsMethodsA total of 2,897 consecutive patients who underwent percutaneous coronary intervention using a drug‐eluting stent for a coronary bifurcation lesion with a side branch (SB) ≥2.3 mm were enrolled from 18 centers in South Korea. We compared target lesion failure (TLF), defined as the composite of cardiac death, myocardial infarction, or target lesion revascularization (TLR) according to 1‐ or 2‐stent techniques in the patients with a de novo Medina 0,0,1 type bifurcation lesion (n = 113, 3.9%)ResultsFifty patients were treated with the 1‐stent technique, and 63 patients with the 2‐stent technique. During a median follow‐up duration of 36.6 months, patients in the 1‐stent technique group tended to have a higher incidence of TLR (3.2 versus 12.0%, P = 0.07) and TLF (4.8 versus 12.0%, P = 0.16) than those in the 2‐stent technique group. Multivariate analysis revealed that the 1‐stent technique was associated with a higher risk of TLR (hazard ratio [HR] 7.35; 95% confidence interval [CI] 1.27–42.5; P = 0.03) and TLF (HR 4.65; 95% CI 1.01–21.6; P = 0.05) than the 2‐stent techniqueConclusionsIn patients with a Medina 0,0,1 type bifurcation lesion, the 2‐stent technique seems to be associated with a better clinical outcome compared with the 1‐stent technique. These findings need to be confirmed in randomized controlled trials. © 2014 Wiley Periodicals, Inc.
The relationship between DRD4 polymorphisms and phenotypic correlations of behaviors in the collared flycatcher
Authors: Garamszegi László Z. , Mueller Jakob C. , Markó Gábor , Szász Eszter , Zsebők Sándor , Herczeg Gábor , Eens Marcel , Török János 
Published: March 2014

AbstractThere is increasing evidence that the genetic architecture of exploration behavior includes the dopamine receptor D4 gene (DRD4). Such a link implies that the within‐individual consistency in the same behavior has a genetic basis. Behavioral consistency is also prevalent in the form of between‐individual correlation of functionally different behaviors; thus, the relationship between DRD4 polymorphism and exploration may also be manifested for other behaviors. Here, in a Hungarian population of the collared flycatcher, Ficedula albicollis, we investigate how males with distinct DRD4 genotypes differ in the consistent elements of their behavioral displays during the courtship period. In completely natural conditions, we assayed novelty avoidance, aggression and risk‐taking, traits that were previously shown repeatable over time and correlate with each other, suggesting that they could have a common mechanistic basis. We identified two single‐nucleotide polymorphisms (SNP554 and SNP764) in the exon 3 of the DRD4 gene by sequencing a subsample, then we screened 202 individuals of both sexes for these SNPs. Focusing on the genotypic variation in courting males, we found that “AC” heterozygote individuals at the SNP764 take lower risk than the most common “AA” homozygotes (the “CC” homozygotes were not represented in our subsample of males). We also found a considerable effect size for the relationship between SNP554 polymorphism and novelty avoidance. Therefore, in addition to exploration, DRD4 polymorphisms may also be associated with the regulation of behaviors that may incur fear or stress. Moreover, polymorphisms at the two SNPs were not independent indicating a potential role for genetic constraints or another functional link, which may partially explain behavioral correlations.
A morphometric and taxonomic study of Monstera (Araceae) in Bahia, Brazil
Authors: Mayo Simon J. , Andrade Ivanilza M. 
Published: March 2014

AbstractA taxonomic revision is presented of the three taxa of Monstera (Araceae) recognized for Bahia State, Brazil:– M. adansonii subsp. blanchetii (stat. nov.), M. adansonii subsp. klotzschiana (stat. nov.) and M. praetermissa; a fourth taxon, not so far recorded from the state, M. adansonii subsp. laniata (stat. nov.), is distinguished from subsp. blanchetii. The two highly variable subspecies of Monstera adansonii were further investigated by morphometric study of herbarium specimens. These two taxa were distinguished using principal coordinates analysis (classical multidimensional scaling) and linear discriminant analysis; the most important diagnostic characters are stigma length and width, stigmatophore length, style apex size and leaf perforation number. Discrimination on leaf characters alone was over 90% successful – subsp. blanchetii differs most significantly from subsp. klotzschiana in higher values for perforation number and leaf base angle. Descriptions, illustrations, geographical and conservation status information and a key to the taxa are provided. Two neotypes are proposed (M. maximilianii Engl., M. klotzschiana Schott) and discussions of the typifications are provided. (© 2013 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
New insights into roles of intermediate filament phosphorylation and progeria pathogenesis
Authors: Goto Hidemasa , Inagaki Masaki 
Published: March 2014

AbstractIntermediate filaments (IFs) form one of the major cytoskeletal systems in the cytoplasm or beneath the nuclear membrane. Because of their insoluble nature, cellular IFs had been considered to be stable for a long time. The discovery that a purified protein kinase phosphorylated a purified IF protein and in turn induced the disassembly of IF structure in vitro led to the novel concept of dynamic IF regulation. Since then, a variety of protein kinases have been identified to phosphorylate IF proteins such as vimentin in a spatiotemporal regulated manner. A series of studies using cultured cells have demonstrated that preventing IF phosphorylation during mitosis inhibits cytokinesis by the retention of an IF bridge‐like structure (IF‐bridge) connecting the two daughter cells. Knock‐in mice expressing phosphodeficient vimentin variants developed binucleation/aneuploidy in lens epithelial cells, which promoted microophthalmia and lens cataract. Therefore, mitotic phosphorylation of vimentin is of great importance in the completion of cytokinesis, the impairment of which promotes chromosomal instability and premature aging. © 2014 IUBMB Life, 66(3):195–200, 2014
Characterization and in vitro differentiation potency of early‐passage canine amnion‐ and umbilical cord‐derived mesenchymal stem cells as related to gestational age
Authors: Filioli Uranio Manuel , Dell'Aquila Maria Elena , Caira Michele , Guaricci Antonio Ciro , Ventura Mario , Catacchio Claudia RITA , Martino Nicola Antonio , Valentini Luisa 
Published: March 2014

SUMMARYFetal adnexa are a non‐controversial source of mesenchymal stem cells (MSCs) that have high plasticity, a high proliferation rate, and the ability to differentiate towards multiple lineages. MSC populations have been characterized for their stemness and differentiation capabilities; more recent work has focused on MSC selection and on establishing predictable elements to discriminate the cells with the most potential for regenerative medicine. In this study, we cytogenetically and molecularly characterized and followed the in vitro proliferation and differentiation potential of early‐passage canine amniotic membrane MSCs (AM‐MSCs) and umbilical cord matrix MSCs (UCM‐MSCs) isolated from fetuses at early (35–40 days) and late (45–55 days) gestational ages. We found that cells from both fetal gestational ages showed similar features. In all examined cell lines, the morphology of proliferating cells typically appeared fibroblast‐like. Population doublings, passaged up to 10 times, increased significantly with passage number. In both cell types, cell viability and chromosomal number and structure were not affected by gestational age at early passages. Passage‐3 AM‐ and UCM‐MSCs from both gestational phases also expressed embryonic (POU5F1) and mesenchymal (CD29, CD44) stemness markers, whereas hematopoietic and histocompatibility markers were never found in any sample. Passage‐3 cell populations of each cell type were also multipotential as they could differentiate into neurocytes and osteocytes, based on cell morphology, specific stains, and molecular analysis. These results indicated that MSCs retrieved from the UCM and AM in the early and late fetal phases of gestation could be used for canine regenerative medicine. Mol. Reprod. Dev. 81: 539–551, 2014. © 2014 Wiley Periodicals, Inc.
Lipidic polyols using thiol‐ene/yne strategy for crosslinked polyurethanes
Authors: Pham Phuoc Dien , Lapinte Vincent , Raoul Yann , Robin Jean‐Jacques 
Published: March 2014

ABSTRACTOleic acid and α,ω‐diacid were converted into propargylic esters followed by thiol‐ene/yne coupling (TEC/TYC) functionalization in presence of mercaptoethanol. The multiradical addition on fatty esters leads to the formation of lipidic polyols (OH1 and OH2), as judged by 1H NMR and mass spectroscopies as well as by size exclusion chromatography. The crosslinking reaction between TEC/TYC‐based polyols and 4,4′‐methylene bis(phenylisocyanate) isocyanate reactant was monitored by FTIR experiment and reaction parameters were optimized. By differential scanning calorimetry, relatively high glass transitions are measured corresponding to structure with little or without dangling chain. Moreover, the thermal stability of the resulting plant oil‐based polyurethane materials (PU1 and PU2) were found to be fully consistent with that of other lipidic PUs respecting a three‐step process. Thanks to TYC methodology, fatty α,ω‐diacid produces lipidic polyol without dangling chain and lipidic thermoset PU with relatively high Tg. © 2014 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2014, 52, 1597–1606
Crystallization of the mesomorphic form and control of the molecular structure for tailoring the mechanical properties of isotactic polypropylene
Authors: De Rosa Claudio , Auriemma Finizia , Di Girolamo Rocco , de Ballesteros Odda Ruiz 
Published: March 2014

ABSTRACTThe combination of the control of the concentration of stereodefects in isotactic polypropylene using metallocene catalysts and the crystallization via the mesophase is a strategy to tailor the mechanical properties. Stiff materials, flexible materials, and thermoplastic elastomers can be produced depending only on the concentration of rr stereodefects. Modulus, ductility, and strength can be modulated through the crystallization of α and γ forms or of the mesophase. Different morphologies are observed depending on the stereoregularity and conditions of crystallization. Crystals of the mesomorphic form always exhibit a nodular morphology, accounting for the similar good deformability of all quenched samples, whatever the concentration of stereodefects. The mesophase transforms by thermal treatments into the α form preserving the nodular morphology, with increase of strength while maintaining the ductility typical of the mesophase. Annealing of the mesophase permits a precise adjustment of crystallinity and size of nodular crystals offering additional options to modify the mechanical properties. © 2014 Wiley Periodicals, Inc. J. Polym. Sci., Part B: Polym. Phys. 2014, 52, 677–699
III‐nitride nanowire based light emitting diodes on carbon paper
Authors: Mastro Michael A. , Anderson Travis J. , Tadjer Marko J. , Kub Francis J. , Hite Jennifer K. , Kim Jihyun , Eddy Charles R. 
Published: March 2014

AbstractThis article presents the use of flexible carbon substrates for the growth of III‐nitride nanowire light emitters. A dense packing of gallium nitride nanowires were grown on a carbon paper substrate. The nanowires grew predominantly along the a‐plane direction, normal to the local surface of the carbon paper. Strong photo‐ and electro‐luminescence was observed from InGaN quantum well light emitting diode nanowires. (© 2014 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Crystalline quality improvement of GaN coalesced using nano‐PSS with void‐embedded nanostructure by MOVPE
Authors: Li Junze , Chen Zhizhong , Jiang Xianzhe , Hu Zhe , Kang Xiangning , Zhang Guoyi 
Published: March 2014

AbstractThe nanoscale patterned sapphire substrates (NPSS) were prepared combining nanoimprint lithography and dry/wet etching technology. The NPSS was patterned with 300 nm diameter, 330 nm depth, 550 nm periodicity hexagonal close packed pillars. Coalescence of GaN has been achieved on the NPSS using MOVPE. The growth mode and conditions were discussed in detail, which was different from that of GaN epitaxial on planar sapphire. The AFM images showed the GaN on NPSS had a smoother surface, and the XRD results showed that the crystal quality had been improved by the NPSS. The threading dislocation density (TDD) suppression was observed in transmission electron microscopy. Depth‐resolved CL measurements were used to quantify the redshift in terms of bandgap renormalization and strain effects. It was supposed that the compressive stress in the GaN layers was changed gradually towards the growth surface. (© 2014 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
First‐principles theoretical study of optical properties of oxygen‐doped II‐VI semiconductors
Authors: Ishikawa Masato , Nakayama Takashi 
Published: March 2014

AbstractDoping properties of oxygen into zinc‐family II‐VI semiconductors were studied by the first‐principles calculation. We found that a large band‐gap reduction occurs for ZnS and ZnSe, while there is little reduction and appears a deep level of oxygen in the band gap for ZnTe. Such difference was shown to reflect the order of energy positions of host cation (Zn) 4s‐orbital and oxygen (O) 3s‐orbital states. We also calculated photoabsorption spectra, ε2(ω), and found that oxygen‐related transitions are strong in case of ZnTe due to localized nature of deep level, while transitions are embedded in the band‐to‐band adsorption in cases of ZnS and ZnSe due to strong hybridization of unoccupied states of O and II‐VI semiconductors. (© 2014 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Deposition of polycrystalline Cd1‐xZnx Te films on ZnTe/graphite and graphite substrates by close‐spaced sublimation
Authors: Okamoto Tamotsu , Akiba Sho , Takahashi Kohei , Nagatsuka Satsuki , Kanda Yohei , Tokuda Satoshi , Kishihara Hiroyuki , Sato Toshiyuki 
Published: March 2014

AbstractThe effects of a ZnTe layer on the deposition of a Cd1‐xZnxTe (CZT) layer in the initial stage of the close‐spaced sublimation (CSS) deposition were investigated. The deposition rate was almost constant in the initial stage of the CdTe deposition on the ZnTe/graphite substrates. However, the deposition rate within 1 minute was lower than that after 1 minute in the CdTe deposition on graphite substrates. This result suggests that nucleation of CdTe directly deposited on graphite substrate is difficult when compared to that with a ZnTe layer. Furthermore, the effects of CdCl2 and ZnTe additions to the CdTe sources in the CSS deposition were also investigated. Both the grain size and the intensity of donor‐acceptor pair (DAP) emission in photoluminescence (PL) spectra were decreased by the effect of CdCl2 addition. Zn content in CZT films was controlled by the ZnTe ratio in the CdTe/ZnTe powder sources. (© 2014 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Estimation of band gap energy of Mgx Zn1‐xO films by photocurrent
Authors: Abe Takami , Nakagawa Akira , Chiba Tetsuya , Nakagawa Michiko , Takahashi Shuzo , Chiba Shigeki , Kashiwaba Yasuhiro , Ojima Tsutomu , Aota Katsumi , Daibo Masahiro , Niikura Ikuo , Kashiwaba Yasube , Osada Hiroshi 
Published: March 2014

AbstractThe band gap energy (Eg) of high‐quality Mgx Zn1‐xO films grown on ZnO (0001) substrates by the plasma‐assisted reactive evaporation method using a ZnMg alloy could be estimated by the photocurrent (Iph). Measurement of Iph was more useful than photoluminescence (PL), transmittance or reflectance (R) spectra measurements for determination of Eg of materials with large binding energy of the excitons. The values estimated from the relation of (αkhν)2–hv plots using optical absorption coefficient αk calculated from extinction coefficient k were close to the peak energy of PL or R of these films. The values estimated from the relation of (αphhv)2–hν plots using inter‐band absorption coefficient αph calculated from Iph spectra were larger than the values of peak energy of PL or R despite strong absorption of the excitons. Therefore, it was thought that these values are closer to Eg. (© 2014 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Erectile Dysfunction Among HIV Patients Undergoing Highly Active Antiretroviral Therapy: Dyslipidemia as a Main Risk Factor
Authors: Romero-Velez Gustavo , Lisker-Cervantes Andrés , Villeda-Sandoval Christian I. , Sotomayor de Zavaleta Mariano , Olvera-Posada Daniel , Sierra-Madero Juan Gerardo , Arreguin-Camacho Lucrecia O. , Castillejos-Molina Ricardo A. 
Published: March 2014

Abstract

Objective
To assess the prevalence and risk factors of erectile dysfunction (ED) in HIV patients from the HIV clinic of a tertiary referral center in Mexico City.

Design
Prevalence was obtained from cross-sectional studies, and the International Index of Erectile Function (IIEF), a standardized method, was used to assess ED.

Methods
A cross-sectional study was performed in the HIV clinic. Participants completed the IIEF to allow ED assessment. Information on demographics, clinical and HIV-related variables was retrieved from their medical records.

Results
One hundred and nine patients were included, with a mean age of 39.9 ± 8.8 years. ED was present in 65.1% of the individuals. Patients had been diagnosed with HIV for a mean of 92.7 ± 70.3 months and had undergone a mean 56.4 ± 45.5 months of HAART. The only variable associated with ED in the univariate analysis was dyslipidemia, and this association was also found in the multivariate analysis (P = 0.01).

Conclusions
ED is highly prevalent in HIV patients. Dyslipidemia should be considered as a risk factor for ED in HIV patients.
Sexual dimorphism and courtship behavior in Drosophila prolongata
Authors: Setoguchi Shiori , Takamori Hisaki , Aotsuka Tadashi , Sese Jun , Ishikawa Yukio , Matsuo Takashi 
Published: March 2014

Abstract
Sexual dimorphism is often derived from sexual selection. In sexually dimorphic Drosophila species, exaggerated male structures are used for specific behaviors in male-to-male competition or courtship toward females. In Drosophila prolongata, a member of the melanogaster species group, males have enlarged forelegs whereas females do not. However, the adaptive role of the enlarged forelegs is unclear because little is known about the behavior of D. prolongata. In this study, the courtship behavior of D. prolongata was investigated in comparison with closely related species. Males of D. prolongata use their forelegs in a specific behavior, “leg vibration”, in which the male vigorously vibrates the female’s abdomen by extending his forelegs from in front of her. Leg vibration was observed immediately before “attempting copulation”, indicating that it has an adaptive role in the mating process. In contrast, leg vibration was not observed in closely related species. Because the large forelegs are necessary to accomplish leg vibration, it was suggested that the sexual dimorphism of D. prolongata forelegs is currently under the influence of sexual selection in courtship behavior.
Cross‐Sectional Associations of Food Consumption with Plasma Fatty Acid Composition and Estimated Desaturase Activities in Finnish Children
Authors: Venäläinen Taisa , Schwab Ursula , Ågren Jyrki , de Mello Vanessa , Lindi Virpi , Eloranta Aino‐Maija , Kiiskinen Sanna , Laaksonen David , Lakka Timo A. 
Published: March 2014

AbstractPlasma fatty acid (FA) composition is known to be an indicator of dietary fat quality, but the associations of other dietary factors with plasma FA composition remain unknown in children. We investigated the cross‐sectional associations of food consumption with the proportions of FA and estimated desaturase activities in plasma cholesteryl esters (CE) and phospholipids (PL) among children. The subjects were a population sample of 423 children aged 6–8 years examined at baseline of The Physical Activity and Nutrition in Children (PANIC) Study. We assessed food consumption by food records and plasma FA composition by gas chromatography. We used linear regression models adjusted for age, sex, physical activity and total energy intake to analyze the associations. A higher consumption of vegetable oil‐based margarine (fat 60–80 %) was associated with a higher proportion of linoleic and α‐linolenic acids in plasma CE and PL. A higher consumption of high‐fiber grain products was related to a lower proportion of oleic acid in CE and PL. The consumption of candy was directly associated with the proportion of palmitoleic and oleic acid in plasma CE. The consumption of vegetable oil‐based margarine was inversely associated with estimated stearoyl‐CoA‐desaturase activity in plasma CE and PL and the consumption of candy was directly related to it in plasma CE. The results of our study suggest that plasma FA composition is not only a biomarker for dietary fat quality but also reflects the consumption of high‐fiber grain products and foods high in sugar among children.