bluuebunny/crossref_metadata_2025_split huggingface dataset:
Chinese women faculty in US universities: Transnational experiences and challenges
Authors: Liu Xiangju , Lin Xi , Zhang Guili , Liu Yue 
Published: July 2024

AbstractDue to the distinct language, cultural values, and social structures, dedicated qualitative research is needed to explore the challenges and supports faced by Chinese women faculty (CWF) members in US academia. Adopting a transnational feminist perspective, this study aims to explore how five CWF members navigate various disadvantages arising from the intersections of race, gender, and cultural values in one US institution. The findings indicate that CWF members encounter language barriers, academic authority challenges, and the struggles of balancing work and life. However, findings also show that they strategically navigate language barriers and challenges to their professional authority by establishing their own voices. Additionally, they benefit from mentoring, fostering their academic development, and contributing to their professional growth. Through this study, we aim to shed new lights on the experiences of CWF members in overcoming obstacles and pursuing professional development within US academia.
Functionalized Hydroxyapatite and Curcumin Incorporated Stimuli‐Responsive Low‐Exothermic and Injectable Poly(methyl methacrylate) Bone Cement for the Treatment of Osteomyelitis
Authors: You Tao , Ding Xintian , Zhao Huapeng , Dai Bin , Ye Lei , Zhao Heng , Zhu Xinwei , Zhou Jian , Yin Jun 
Published: July 2024

AbstractWith the increasing of bone diseases, bone substitute biomaterials have been urgently needed and recognized as effective therapeutic strategies for bone regeneration. However, the improper mechanical properties, uncontrolled curing time, and exothermic heat limited their clinical applications. Herein, a facile prepared injectable bone cement consisting of poly(methyl methacrylate), hydroxyapatite, curcumin, oxidized sodium alginate, and polyethylenimine is constructed. By taking advantage of the acid‐ and H2O2‐responsive covalent bonds, the resultant bone cement not only possessed superior compressive strength (>70 MPa), bending strength (>50 MPa), suitable curing time (9–14 min), and low exothermic heat (<42 oC), but also can release the drugs under the trigger of osteomyelitis microenvironment. Both at the cellular level and rat osteomyelitis models, the prepared bone cement exhibited excellent biocompatibility (cell survival rate: >97%; hemolysis ratio: <1.8%), anti‐bacterial (the lowest bacterial survival rate: ≈1.7%), anti‐inflammatory (the expressions of iNOS, CD86, TNF‐α, IL‐1β, and IL‐6 are significantly inhibited) and the ability to promote bone regeneration (proliferation of osteoblasts and inhibition of osteoclasts). It is believed that this work will provide a bioactive organic/inorganic composite material for bone tissue engineering, the distinctive human‐friendly low exothermic heat, and advantages of prodrug technique incorporated multi‐function integration endow them potential clinical application prospects.
Wavelength‐Selective Photodetector and Neuromorphic Visual Sensor Utilizing Intrinsic Defect Semiconductor
Authors: Wang Peng , Xue Wuhong , Zeng Jianmin , Ci Wenjuan , Chen Qilai , Lv Baohua , Yang Ruilong , Liu Yang , Liu Gang , Xu Xiaohong 
Published: July 2024

AbstractWith the rapid developments of Artificial Intelligence (AI) and the Internet of Things (IoT), increasingly intricate and expanding application scenarios are placing higher demands on current machine vision capabilities. Therefore, there is a pressing need to simultaneously achieve diverse functionalities, simple designs, and efficient computing in vision devices. Here, the study develops a two‐terminal optoelectronic device utilizing a single 2D intrinsic defect semiconductor In2S3. The device demonstrates wavelength‐selective photodetection and neuromorphic visual capabilities, attributed to defect‐related charge‐trapping/de‐trapping processes. As a photodetector, the device exhibits a high photoresponsivity of 473.6 A W−1, a high external quantum efficiency of 1.6 × 105%, and a fast rise/fall time of 0.3/1.4 ms at the wavelength of 359 nm. As an all‐in‐one neuromorphic visual device, optoelectronic‐driven fundamental synaptic functions, including paired‐pulse facilitation (PPF), short‐term plasticity (STP), long‐term plasticity (LTP), and “learning‐experience”, are successfully mimicked at the wavelength of 671 nm. Moreover, one‐shot recognition of the 12‐letter image “SHAN XI NORMAL” is achieved through an artificial convolutional neural network. This study provides a new strategy for developing compact high‐level intelligence systems for complex application scenarios.
In Situ Dehydration Condensation of Self‐Assembled Molecules Enables Stabilization of CsPbI3 Perovskites for Efficient Photovoltaics
Authors: Li Tianxiang , Wang Kun , Tong Yu , Qi Heng , Yue Sihong , Li Wan , Wang Hongqiang 
Published: July 2024

AbstractInorganic perovskites, with Cs+ substituting volatile organic components, show great promise in photovoltaic applications due to their outstanding optoelectronic properties and thermal stability. However, the black‐to‐yellow phase transition of CsPbI3 remains a challenge for realizing high‐performance inorganic perovskite solar cells (IPSCs). Herein, an effective approach is reported via incorporating the self‐assembled molecule Me‐4PACz to synergistically stabilize the [PbI6]4− octahedra and form a hydrophobic layer at interface and grain boundaries. An in situ dehydration condensation reaction of Me‐4PACz is observed during film annealing, which favors the reduction of undesired aggregation of Me‐4PACz in humid air, thus leading to enhanced anchoring interaction and more effective hydrophobic protection of CsPbI3. Therefore, the air‐processed CsPbI3 perovskite films show dramatically improved phase purity and humid stability. This strategy also improves the energy level alignment between perovskite and charge transport layers. As a result, a champion efficiency of 20.21% is realized, representing one of the highest reported values for air‐processed inverted IPSCs. Furthermore, it is demonstrated that by combining Me‐4PACz with the previously reported ethacridine lactate (EAL) additive, the device performance can be further boosted to 21.38%, which is a record efficiency for the inverted IPSCs reported to date.
Rutile‐Structured Ru0.48Mn0.52O2 Solid Solution for Highly Active and Stable Oxygen Evolution at Large Current Density in Acidic Media
Authors: Li Zonglin , Sheng Haoyun , Lin Yichao , Hu Hongyan , Sun Hongfei , Dong Yan , Chen Xiaowei , Wei Lingzhi , Tian Ziqi , Chen Qianwang , Su Jianwei , Chen Liang 
Published: July 2024

AbstractThe development of active, stable, and cost‐effective electrocatalysts for the oxygen evolution reaction (OER) in acidic media is crucial for proton‐exchange‐membrane water electrolysis. Inspired by theoretical screening on a series of transition metal incorporated RuO2 systems, a low Ru‐content solid solution oxide (Ru0.48Mn0.52O2) achieved is fabricated by a simple two‐step synthesis method through the combination of rutile RuO2 and β‐MnO2. The Ru0.48Mn0.52O2 catalyst exhibits an exceptionally low overpotential of 154 mV at 10 mA cm−2 and maintains a high stability under a high current of 100 mA cm−2 for 50 h in 0.5 m H2SO4 electrolyte. Furthermore, the obtained catalyst exhibits sustained stability at a large current of 0.5 A cm−2 for at least 50 h when loaded onto a Ti felt. The in‐situ characterization results indicate that Ru0.48Mn0.52O2 preferably followed the adsorbate evolution mechanism rather than the lattice oxygen oxidation mechanism during the OER process, contributing to its high activity and stability at large current densities in acidic media.
Single‐Monolayer Na2S Film on Metal Surfaces
Authors: Wei Peng , Yang Yuxiang , Liu Chang‐Jun , Gao Hong‐Ying 
Published: July 2024

AbstractNa2S is a key material in sodium‐sulfur batteries and its single‐monolayer film may also be a new 2D material. Herein, the results are first reported by STM, XPS, and DFT simulation that the Na2S single‐monolayer film shows different atomic structures depending on the underlying metals, and these structures can be changed by thermal annealing. All structures are well supported by DFT simulation on corresponding Na2S up, down, and standing models, as well as the NaS in‐plane model. Further, a wide bandgap of Na2S single‐monolayer film is measured, which decreases from Au(111) to Ag(111) and Cu(111) due to the different Na2S interactions with metal substrates. Finally, it is demonstrated that dibenzo 18‐crown‐6‐ether molecules can grow on phase VI of Na2S film at room temperature, as compared with preferred metal surfaces and Na2S phase III structure.
Injectable Gelled Multiple Emulsion for Glucose‐Responsive Insulin Delivery
Authors: Boakye‐Yiadom Kofi Oti , Chen Qijing , Teng Yilong , Zhang Chenshuang , Hu Bin , Zhang Xue‐Qing 
Published: July 2024

AbstractA glucose‐responsive insulin delivery system that sustains blood glucose equilibrium for an extended duration can address the low therapeutic window of insulin in diabetes treatment. Herein, insulin is loaded in a water‐in‐oil‐in‐water (W1/O/W2) gelled multiple emulsion using poly (4‐vinylphenylboronic acid) (PVPBA) homopolymer as an effective emulsifier. The gelled multiple emulsion exhibits a high encapsulation efficiency (99%), enhanced stability and remarkable shear‐thinning behavior, making it easy to inject. Under hyperglycemic conditions, the gelled emulsion system instantly binds to glucose molecules and reduces the hydrogen bonds of the PVPBA homopolymer, resulting in insulin release. In a streptozotocin‐induced type 1 diabetic mouse model, a single subcutaneous injection of the gelled emulsion rapidly responds to high blood glucose concentration (BGC) and release insulin in a glucose dependent manner, thus prolonging the antihyperglycemic effect compared with free insulin.
Zwitterionic Poly‐Carboxybetaine Polymers Restore Lubrication of Inflamed Articular Cartilage
Authors: Weber Patrick , Asadikorayem Maryam , Zenobi‐Wong Marcy 
Published: July 2024

AbstractOsteoarthritis is a degenerative joint disease that is associated with decreased synovial fluid viscosity and increased cartilage friction. Though viscosupplements are available for decades, their clinical efficacy is limited and there is ample need for more effective joint lubricants. This study first evaluates the tribological and biochemical properties of bovine articular cartilage explants after stimulation with the inflammatory cytokine interleukin‐1β. This model is then used to investigate the tribological potential of carboxybetaine (CBAA)‐based zwitterionic polymers of linear and bottlebrush architecture. Due to their affinity for cartilage tissue, these polymers form a highly hydrated surface layer that decreases friction under high load in the boundary lubrication regime. For linear pCBAA, these benefits are retained over several weeks and the relaxation time of cartilage explants under compression is furthermore decreased, thereby potentially boosting the weeping lubrication mechanism. Bottlebrush bb‐pCBAA shows smaller benefits under boundary lubrication but is more viscous than linear pCBAA, therefore providing better lubrication under low load in the fluid‐film regime and enabling a longer residence time to bind to the cartilage surface. Showing how CBAA‐based polymers restore the lost lubrication mechanisms during inflammation can inspire the next steps toward more effective joint lubricants in the future.
Robust Ferrimagnetism and Ferroelectricity in 2D ɛ‐Fe2O3 Semiconductor with Ultrahigh Ordering Temperature
Authors: Wang Tao , Xue Wuhong , Yang Huali , Zhang Yongzhao , Cheng Shaobo , Fan Zhiwei , Li Run‐Wei , Zhou Peng , Xu Xiaohong 
Published: July 2024

Abstract2D single‐phase multiferroic materials with the coexistence of electric and spin polarization offer a tantalizing potential for high‐density multilevel data storage. One of the current limitations for application is the scarcity of the materials, especially those combine ferromagnetism and ferroelectricity at high temperatures. Here, robust ferrimagnetism and ferroelectricity in 2D ɛ‐Fe2O3 samples with both single‐crystalline and polycrystalline form are demonstrated. Interestingly, the polycrystalline nanosheets also exhibit easily switchable ferroelectric polarizations comparable to that of single crystals. The existence of grain boundary does not hinder the switching and retention of ferroelectric polarization. Furthermore, the ɛ‐Fe2O3 nanosheets show ferrimagnetic and ferroelectric Curie temperatures up to 800 K, which reaches record highs in 2D single‐phase multiferroic materials. This work provides important progress in the exploration of 2D high‐temperature single‐phase multiferroics for potentially compact high‐temperature information nanodevices.
Enhancement of Interlayer Exciton Emission in a TMDC Heterostructure via a Multi‐Resonant Chirped Microresonator Upto Room Temperature
Authors: Palekar Chirag C. , Rosa Barbara , Heermeier Niels , Shih Ching‐Wen , Limame Imad , Koulas‐Simos Aris , Rahimi‐Iman Arash , Reitzenstein Stephan 
Published: July 2024

AbstractWe report on multi‐resonance chirped distributed Bragg reflector (DBR) microcavities. These systems are employed to investigate the light‐mater interaction with both intra‐ and inter‐layer excitons of transition metal dichalcogenide (TMDC) bilayer heterostructures. The chirped DBRs consisting of SiO2 and Si3N4 layers of gradually varying thickness exhibit a broad stopband with a width exceeding 600 nm. Importantly, the structures provide multiple resonances across a broad spectral range, which can be matched to resonances of the embedded TMDC heterostructures. Studying cavity‐coupled emission of both intra‐ and inter‐layer excitons from an integrated WSe2/MoSe2 heterostructure in a chirped microcavity system, an enhanced interlayer exciton emission with a Purcell factor of 6.67 ± 1.02 at 4 K is observed. The cavity‐enhanced emission of the interlayer exciton is used to investigate its temperature‐dependent luminescence lifetime of 60 ps at room temperature. The cavity system modestly suppresses intralayer exciton emission by intentional detuning, thereby promoting a higher IX population and enhancing cavity‐coupled interlayer exciton emission. This approach provides an intriguing platform for future studies of energetically distant and confined excitons in different semiconducting materials, which paves the way for various applications such as microlasers and single‐photon sources by enabling precise emission control and utilizing multimode resonance light‐matter interaction.
Identifying the Origin of Thermal Modulation of Exchange Bias in MnPS3/Fe3GeTe2 van der Waals Heterostructures
Authors: Puthirath Balan Aravind , Kumar Aditya , Reiser Patrick , Vimal Vas Joseph , Denneulin Thibaud , Lee Khoa Dang , Saunderson Tom G. , Tschudin Märta , Pellet‐Mary Clement , Dutta Debarghya , Schrader Carolin , Scholz Tanja , Geuchies Jaco , Fu Shuai , Wang Hai , Bonanni Alberta , Lotsch Bettina V. , Nowak Ulrich , Jakob Gerhard , Gayles Jacob , Kovacs Andras , Dunin‐Borkowski Rafal E. , Maletinsky Patrick , Kläui Mathias 
Published: July 2024

AbstractThe exchange bias phenomenon, inherent in exchange‐coupled ferromagnetic and antiferromagnetic systems, has intrigued researchers for decades. Van der Waals materials, with their layered structures, offer an ideal platform for exploring exchange bias. However, effectively manipulating exchange bias in van der Waals heterostructures remains challenging. This study investigates the origin of exchange bias in MnPS3/Fe3GeTe2 van der Waals heterostructures, demonstrating a method to modulate nearly 1000% variation in magnitude through simple thermal cycling. Despite the compensated interfacial spin configuration of MnPS3, a substantial 170 mT exchange bias is observed at 5 K, one of the largest observed in van der Waals heterostructures. This significant exchange bias is linked to anomalous weak ferromagnetic ordering in MnPS3 below 40 K. The tunability of exchange bias during thermal cycling is attributed to the amorphization and changes in the van der Waals gap during field cooling. The findings highlight a robust and adjustable exchange bias in van der Waals heterostructures, presenting a straightforward method to enhance other interface‐related spintronic phenomena for practical applications. Detailed interface analysis reveals atom migration between layers, forming amorphous regions on either side of the van der Waals gap, emphasizing the importance of precise interface characterization in these heterostructures.
Novel Delivery Systems for Oral Administration of Enfuvirtide: New Treatment Options for HIV/AIDS
Authors: Pang Huiwen , Qu Zhi , Kumar Vinod , Wang Yinuo , Wu Youzhi , Lin Min‐Hsuan , Harrich David , Han Felicity Y. 
Published: July 2024

AbstractEnfuvirtide (T‐20) is a synthetic peptide fusion inhibitor for the human immunodeficiency virus (HIV), which causes acquired immunodeficiency syndrome (AIDS). However, the peptide nature limits a wider application of T‐20 with subcutaneous injection (Fuzeon) the only available formulation. In this groundbreaking study, it is sought to overcome this limitation by employing poly lactic‐co‐glycolic acid (PLGA) and alginate to create novel oral delivery systems for T‐20. Remarkably, this investigation marks the first instance of assessing the efficacy of oral delivery systems in mice. Notably, both the PLGA and alginate formulations exhibit the capability to sustain T‐20 release, maintaining detectable levels in the bloodstream of mice for over 24 h after a single dose. By venturing into the realm of oral T‐20 delivery, this study opens avenues for the prospective development of oral formulations of T‐20, potentially leading to their evaluation in clinical trials.
Designer Solvents for Pharmaceutics: Role of Ionic Liquids/ Deep Eutectic Solvents in Pharmaceutical Formulations
Authors: Dhiman Diksha , Alhammadi Munirah , Kim Hanseung , Umapathi Reddicherla , Huh Yun Suk , Venkatesu Pannuru 
Published: July 2024

AbstractThe design of biologic and synthetic drugs in the pharmaceutical industry is facing three key challenges, namely, ensuring bioavailability, solubility, and stability. Ionic liquids (ILs) and deep eutectic solvents (DESs), classified as designer solvents, have emerged as excellent solvents for improving the permeability and stability of biotherapeutic drugs. Moreover, they have shown remarkable solubilizing effects for synthetic drugs, particularly in solubilizing active pharmaceutical ingredients (API), and are known as eco‐friendly solvents. Thus, in this review, the development of designer formulations in pharmaceutical industries is reported, and the underlying strategies for designing the most efficient formulations for both biotherapeutics and synthetic drugs are examined.
Spectrum Reconstruction Model Based on Multispectral Electrochromic Devices
Authors: Wang Shuo , Yin Hang , Li Yang , Du Zhen , Zhang Yu‐Mo , Zhang Sean Xiao‐An 
Published: July 2024

AbstractReconstructing the visible spectra of real objects is critical to the spectral camouflage from emerging spectral imaging. Electrochromic materials exhibit unique superiority for this goal due to their subtractive color‐mixing model and structural diversity. Herein, a simulation model is proposed and a method is developed to fabricate electrochromic devices for dynamically reproducing the visible spectrum of the natural leaf. Over 20 kinds of pH‐dependent leuco dyes have been synthesized/prepared through molecular engineering and offered available spectra/bands to reconstruct the spectrum of the natural leaf. More importantly, the spectral variance between the device and leaf is optimized from an initial 98.9 to an ideal 10.3 through the simulation model, which means, the similarity increased nearly nine‐fold. As a promising spectrum reconstruction approach, it will promote the development of smart photoelectric materials in adaptive camouflage, spectral display, high‐end encryption, and anti‐counterfeiting.
Overcoming Cancer Persister Cells by Stabilizing the ATF4 Promoter G‐quadruplex
Authors: Xiao Chengmei , Li Yipu , Liu Yushuang , Dong Ruifang , He Xiaoyu , Lin Qing , Zang Xin , Wang Kaibo , Xia Yuanzheng , Kong Lingyi 
Published: July 2024

AbstractPersister cells (PS) selected for anticancer therapy have been recognized as a significant contributor to the development of treatment‐resistant malignancies. It is found that imposing glutamine restriction induces the generation of PS, which paradoxically bestows heightened resistance to glutamine restriction treatment by activating the integrated stress response and initiating the general control nonderepressible 2‐activating transcription factor 4‐alanine, serine, cysteine‐preferring transporter 2 (GCN2‐ATF4‐ASCT2) axis. Central to this phenomenon is the stress‐induced ATF4 translational reprogramming. Unfortunately, directly targeting ATF4 protein has proven to be a formidable challenge because of its flat surface. Nonetheless, a G‐quadruplex structure located within the promoter region of ATF4 (ATF4‐G4) is uncovered and resolved, which functions as a transcriptional regulator and can be targeted by small molecules. The investigation identifies the natural compound coptisine (COP) as a potent binder that interacts with and stabilizes ATF4‐G4. For the first time, the high‐resolution structure of the COP‐ATF4‐G4 complex is determined. The formation of this stable complex disrupts the interaction between transcription factor AP‐2 alpha (TFAP2A) and ATF4‐G4, resulting in a substantial reduction in intracellular ATF4 levels and the eventual death of cancer cells. These seminal findings underscore the potential of targeting the ATF4‐G4 structure to yield significant therapeutic advantages within the realm of persister cancer cells induced by glutamine‐restricted therapy.
De‐Intercalation of Iodoplumbate(DMSO)x Complex for Uniaxially Oriented Halide Perovskite Thin‐Film Solar Cells
Authors: Park Junhyoung , Kim Seongheon , Chu Young Ho , Lee Jinhyuk , Son Dae‐yong , Choi Mansoo , Lee Yun Seog 
Published: July 2024

AbstractOrganic lead halide perovskite solar cells (PSCs) have become a viable alternative for next‐generation photovoltaic systems. The significance of reproducibly processing perovskite with less defects comes from the fact that imperfections have a major impact on the solar cell's performance and long‐term stability. Although it is well known that cautious precursor processing has a significant influence on perovskite defect generation, there haven't been extensive investigations on the serial associations between precursor processing, perovskite orientation, and defect generation in PSCs. Making use of a unique precursor chemistry treatment technique that facilitates uniaxially oriented perovskite growth, it is aimed to mitigate defects of sequentially spin‐coated perovskite. Through the temperature‐dependent configurational entropic effect on coordination between iodoplumbate and dimethylsulfoxide (DMSO), a DMSO de‐intercalation processing method is developed. This method enables the induction of uniaxially‐oriented α‐FA0.9MA0.1PbI3‐xBrx (FA: formamidnium, MA: methylammomnium, x < 0.13) perovskite growth parallel to substrates. As a result, this processing delivered significant advances in power conversion efficiency (24.02%) and ambient operational stability under light. This straightforward technique provides a accesible process for producing efficient and stable perovskite solar cells, enabling uniaxially oriented perovskite fabrication without complicated procedures or additional substances.