bluuebunny/crossref_metadata_2025_split huggingface dataset:
Variable selection for both outcomes and predictors: sparse multivariate principal covariates regression
Authors: Park Soogeun , Ceulemans Eva , Van Deun Katrijn 
Published: July 2024

AbstractDatasets comprised of large sets of both predictor and outcome variables are becoming more widely used in research. In addition to the well-known problems of model complexity and predictor variable selection, predictive modelling with such large data also presents a relatively novel and under-studied challenge of outcome variable selection. Certain outcome variables in the data may not be adequately predicted by the given sets of predictors. In this paper, we propose the method of Sparse Multivariate Principal Covariates Regression that addresses these issues altogether by expanding the Principal Covariates Regression model to incorporate sparsity penalties on both of predictor and outcome variables. Our method is one of the first methods that perform variable selection for both predictors and outcomes simultaneously. Moreover, by relying on summary variables that explain the variance in both predictor and outcome variables, the method offers a sparse and succinct model representation of the data. In a simulation study, the method performed better than methods with similar aims such as sparse Partial Least Squares at prediction of the outcome variables and recovery of the population parameters. Lastly, we administered the method on an empirical dataset to illustrate its application in practice.
ICM ensemble with novel betting functions for concept drift
Authors: Eliades Charalambos , Papadopoulos Harris 
Published: July 2024

AbstractThis study builds upon our previous work by introducing a refined Inductive Conformal Martingale (ICM) approach for addressing Concept Drift. Specifically, we enhance our previously proposed CAUTIOUS betting function to incorporate multiple density estimators for improving detection ability. We also combine this betting function with two base estimators that have not been previously utilized within the ICM framework: the Interpolated Histogram and Nearest Neighbor Density Estimators. We assess these extensions using both a single ICM and an ensemble of ICMs. For the latter, we conduct a comprehensive experimental investigation into the influence of the ensemble size on prediction accuracy and the number of available predictions. Our experimental results on four benchmark datasets demonstrate that the proposed approach surpasses our previous methodology in terms of performance while matching or in many cases exceeding that of three contemporary state-of-the-art techniques.
A novel method of reconstructing planar flow field from given distribution of single velocity component: comparison to conventional divergence-free approach
Authors: Shimano Kenjiro , Shiratori Suguru , Nagano Hideaki 
Published: July 2024

AbstractMeasurements of a single flow velocity component are still prevalent due to their reasonable costs and some difficulties in multiple-component measurements. If the transverse component can be obtained additionally by a numerical technique, qualitative features of the flow will be understood more effectively. In this context, methods based on the 2-dimensonal divergence-free assumption have been widely used for problems in which a single velocity component is measured over a planar domain. In this study, the authors proposed a method of approximating the second planar velocity component by minimising an objective function expressed with divergence and vorticity so that the mass transport in the out-of-plane direction could be taken into consideration. The present method was tested with numerically produced 3-dimensional flows in a hexahedral chamber and a flow around a bluff body measured by particle image velocimetry. There was a tendency that the present method calculated the second velocity component with smaller errors than existing divergence-free approaches. It was also shown that the present method had a high capability to locate strong suction and generation caused by the mass transport in the out-of-plane direction. The present method is deemed promising for many one-component flow measurements in engineering and medicine.
Melding Boolean networks and reaction systems under synchronous, asynchronous and most permissive semantics
Authors: Bruni Roberto , Gori Roberta , Milazzo Paolo , Siboulet Hélène 
Published: July 2024

AbstractThis paper forges a strong connection between two well known computational frameworks for representing biological systems, in order to facilitate the seamless transfer of techniques between them. Boolean networks are a well established formalism employed from biologists. They have been studied under different (synchronous and asynchronous) update semantics, enabling the observation and characterisation of distinct facets of system behaviour. Recently, a new semantics for Boolean networks has been proposed, called most permissive semantics, that enables a more faithful representation of biological phenomena. Reaction systems offer a streamlined formalism inspired by biochemical reactions in living cells. Reaction systems support a full range of analysis techniques that can help for gaining deeper insights into the underlying biological phenomena. Our goal is to leverage the available toolkit for predicting and comprehending the behaviour of reaction systems within the realm of Boolean networks. In this paper, we first extend the behaviour of reaction systems to several asynchronous semantics, including the most permissive one, and then we demonstrate that Boolean networks and reaction systems exhibit isomorphic behaviours under the synchronous, general/fully asynchronous and most permissive semantics.
Ciliopathies are responsible for short stature and insulin resistance: A systematic review of this clinical association regarding SOFT syndrome
Authors: Perge Kevin , Capel Emilie , Senée Valérie , Julier Cécile , Vigouroux Corinne , Nicolino Marc 
Published: July 2024

AbstractSOFT syndrome (Short stature-Onychodysplasia-Facial dysmorphism-hypoTrichosis) is a rare primordial dwarfism syndrome caused by biallelic variants in POC1A encoding a centriolar protein. To refine the phenotypic spectrum of SOFT syndrome, recently shown to include metabolic features, we conducted a systematic review of all published cases (19 studies, including 42 patients). The SOFT tetrad affected only 24 patients (57%), while all cases presented with short stature from birth (median height: -5.5SDS([-8.5]-[-2.8])/adult height: 132.5 cm(103.5–148)), which was most often disproportionate (90.5%), with relative macrocephaly. Bone involvement resulted in short hands and feet (100%), brachydactyly (92.5%), metaphyseal (92%) or epiphyseal (84%) anomalies, and/or sacrum/pelvis hypoplasia (58%). Serum IGF-I was increased (median IGF-I level: + 2 SDS ([-0.5]-[+ 3])). Recombinant human growth hormone (rhGH) therapy was stopped for absence/poor growth response (7/9 patients, 78%) and/or hyperglycemia (4/9 patients, 45%). Among 11 patients evaluated, 10 (91%) presented with central distribution of fat (73%), clinical (64%) and/or biological insulin resistance (IR) (100%, median HOMA-IR: 18), dyslipidemia (80%), and hepatic steatosis (100%). Glucose tolerance abnormalities affected 58% of patients aged over 10 years. Patients harbored biallelic missense (52.4%) or truncating (45.2%) POC1A variants. Biallelic null variants, affecting 36% of patients, were less frequently associated with the SOFT tetrad (33% vs 70% respectively, p = 0.027) as compared to other variants, without difference in the prevalence of metabolic abnormalities. POC1A should be sequenced in children with short stature, altered glucose/insulin homeostasis and/or centripetal fat distribution. In patients with SOFT syndrome, rhGH treatment is not indicated, and IR-related complications should be regularly screened and monitored.PROSPERO registration: CRD42023460876.
The Effects of Designing Scientific Experiments with Visual Programming Language on Learning Outcomes
Authors: Kalemkuş Jale , Kalemkuş Fatih 
Published: July 2024

AbstractWhen the studies on the effectiveness of visual programming language are examined, it is seen that studies on coding teaching have been carried out frequently recently. In this study, Scratch was used as a teaching tool in teaching science lessons. In this way, a new perspective has been brought to Scratch applications. In the related study, the effects of designing science experiments with visual programming language (Scratch) on students’ beliefs of self-efficacy related to computational thinking (CT) skills, metacognitive awareness levels, and motivation levels for science learning are examined. This study was carried out using a single-group research design based on pretest and posttest applications. Students attending the fifth grade participated in this study. Sixty-five students attending the fifth grade participated in the research. Research data were obtained using “Self-Efficacy Perception Scale for CT Skills (SEP_CTS),” “Metacognitive Awareness Scale (MAS),” and “Motivation Scale for Science Learning (MSSL).” The research process is 10 weeks and 3 days in total. It was determined that designing science experiments in visual programming language applications based on Scratch improved students’ CT self-efficacy perceptions, but did not have the expected effect on students’ science learning motivation and metacognitive awareness. This research provides evidence that some skills can be improved by using Scratch as a teaching tool in different courses. With the focus of research on this subject, it can contributed to the development of new understandings of Scratch in teaching processes.
Inequality Belief Systems: What They Look Like, How to Study Them, and Why They Matter
Authors: Bertero Arturo , Franetovic Gonzalo , Mijs Jonathan J. B. 
Published: July 2024

AbstractThis paper purports to enrich the burgeoning field of research on the content of people’s beliefs about inequality by studying the structure of these beliefs. We develop a theoretical and methodological framework that combines Correlational Class Analysis and Exploratory Graph Analysis, and we test it empirically with original survey data collected in the United States and the Netherlands (n = 2,501 and 1,618). Using CCA, we identify groups of individuals who share construals of inequality, while EGA allows us to model these structures as inequality belief systems, which are networks of perceptions, explanations and attitudes about inequality. Results reveal the presence of two distinct belief systems in each country. These systems exhibit structural differences and are related to different sociodemographic factors in the U.S. and the Netherlands. Moreover, we show that inequality belief systems are more socially patterned in the former country. Finally, we demonstrate that belief systems, in both countries, are associated with different levels of support for redistribution. We discuss the significance of our findings for the politics of inequality and stress that overlooking attitudinal structures impedes a full understanding of people’s views on inequality and their support for redistribution.
The Complexity of Co-Generative Learning Between University and Regional Actors
Authors: Karlsen James 
Published: July 2024

AbstractThis article reflects on the complexity of co-generative learning processes between a university and regional actors, drawing on the author’s experience facilitating an action research course. The course engages students in collaborating with regional practitioners on real-life territorial development challenges. Through glimpses into the co-generation process from student exam papers, the article highlights the challenges students face in navigating ambiguity and complexity when exposed to real-life territorial issues. Concepts such as regional complexity, Bildung, interiority, and democratic dialogue are used to analyze how structured reflection and facilitation through participation with regional actors can enhance students’ critical capacities for reflection and action. The main theoretical contribution is extending the concept of co-generative learning of Morten Levin and action research for territorial development by integrating students as reflective, facilitative actors in educational and regional development processes. Action research for territorial development provides a framework for accompanying the social transformations needed to address complex challenges. The article shows that by engaging in real-life issues through participatory, reflective processes, students develop crucial skills for facilitating collective territorial development efforts. Despite limitations related to geographic context and the course structure, the insights gained offer valuable implications for applying Levin’s legacy in other contexts.
Plain alethic pluralism: the human face of truth
Authors: Dell’Utri Massimo 
Published: July 2024

AbstractWithin the secular and still ongoing discussion about truth, what is by now known as alethic pluralism has proved to be one of the most interesting proposals advanced in the field. Indeed, from the last decade of the last century onwards, the field of theories about truth has been enriched with the idea that truth is not only one but also many—many alethically potent properties that differently characterise different domains of discourse. Moreover, thirty or so years of discussions have also shown that alethic pluralism itself is many rather than one—a family of views with different metaphysical commitments. As it may happen in all good families, though, some members are neglected or overshadowed. This is the case with the view called “simple alethic pluralism”, and this paper seeks to remedy this. Accordingly, a new kind of simple alethic pluralism (termed “Plain Alethic Pluralism”) is advanced. It highlights the features of the meaning of the word “true”, in particular its focal meaning, while reaffirming the dependence of truth on the world. In drawing attention to the way speakers use the truth-predicate, making it acquire the meaning it has, it intends to qualify as a conception of truth with a human face.
Effect of Clinician Posture on Patient Perceptions of Communication in the Inpatient Setting: A Systematic Review
Authors: Houchens Nathan , Engle Jason M. , Palanjian Rita , Saint Sanjay , Townsend Whitney A. , Nasrallah Mariam , Gupta Ashwin 
Published: July 2024

Abstract
Background
Nonverbal communication plays a pivotal role in the provision of effective patient care and has been associated with important patient health outcomes. Clinician posture, a nonverbal form of communication, may influence the patient experience and satisfaction. The relationship between clinician posture (i.e., standing or at the patient’s eye level) and patient perceptions of clinician communication in the hospital—a setting with heightened power dynamics between patient and clinician—is currently unknown.

Methods
We conducted searches of Ovid MEDLINE, EBSCO CINAHL Complete, EBSCO PsycInfo, Elsevier Embase/Embase Classic, Elsevier Scopus, and Web of Science Core Collection up to May 2023. English language studies were included if they compared clinician posture (eye-level or standing) during adult inpatient (including emergency department) interactions. Two authors independently abstracted data from included studies and assessed risk of bias or quality of evidence. A third author arbitrated any disagreements. Studies reported adherence to the posture intervention and/or patient perception outcomes. The latter included encounter duration, preferences for posture type, perceptions of interaction quality and clinician communication and compassion, and standardized assessments of patient satisfaction.

Results
Fourteen studies (six randomized controlled trials, four quasi-experimental studies, four observational studies) assessed clinician posture at the bedside. Ten noted at least one favorable outcome for clinicians who communicated at the patient’s eye level, three revealed no differences in patient perceptions between standing and sitting, and one noted higher patient ratings for standing clinicians. Findings were limited by variation in interventions and outcomes, generally high risk of bias, and relatively low adherence to assigned posture groups.

Discussion
Compared to standing, eye-level communication by clinicians appears beneficial. The magnitude and types of benefits clinicians and patients may gain from this behavior remain unclear given heterogeneity and generally high risk of bias in available studies. With its relatively easy implementation and potential for benefit, clinicians should consider communicating with their hospitalized patients at eye level.

Registration
PROSPERO, CRD42020199817.
The CD44s Isoform is a Potential Biomarker for Predicting Craniopharyngioma Recurrence in Children
Authors: Bajdak-Rusinek K. , Diak N. , Gutmajster E. , Fus-Kujawa A. , Ciupińska M. , Kalina-Faska B. , Trybus A. , Grajek M. , Kalina M. , Mandera M. 
Published: July 2024

AbstractAdamantinomatous craniopharyngioma (ACP) is an intracranial tumor considered partly malignant due to its ability to infiltrate surrounding structures and tendency to relapse despite radical resection. CD44 is a known stem cell marker in ACP and is upregulated in cell clusters of invasive ACP protrusions; however, the functions of its alternative splicing isoform variants, CD44s and CD44v1-10, have not yet been studied in terms of ACP recurrence, despite their confirmed roles in cancer development and progression. In this study, we first confirmed the difference in total CD44 expression between samples from patients who experienced relapse and those from patients who did not. Moreover, our findings showed that, in recurrent samples, the predominant isoform expressed was CD44s, which might indicate its significance in predicting ACP recurrence. The association between increased CD44 expression and recurrence may lead to the development of prognostic markers of ACP aggressiveness and relapse potential; however, further studies are needed to clarify the exact mechanism of CD44 expression.
Perceptions of journal editors on the use of eponyms in anatomical publishing: the need for compromise
Authors: Bacci Nicholas , Hutchinson Erin , Kramer Beverley , Billings Brendon Kurt 
Published: July 2024

AbstractWhile arguments have been made both for and against the value of anatomical eponyms, limited research exists regarding their use by anatomists. As the editors of the principal international anatomy journals have purview and control of terminology in anatomical journals, their perceptions regarding the relevance, ethics and inclusivity of eponym use in anatomy and in publishing in anatomical journals were investigated. A validated, confidential and anonymized self-administered questionnaire which included open-ended questions was distributed to the 22 Editor-in-Chiefs/Senior Editors of anatomical journals. Of the 16 (73%) editors who responded to the survey, only 56% were aware that eponyms had been censured since the time of the 1895 Nomina Anatomica. The majority of responding editors found the use of Latin- and Greek-derived terms more valuable when communicating with students and peers, but also thought eponyms were acceptable in manuscripts submitted to their journals. Thirteen (81%) of the responding editors agreed that eponyms play a vital role in the history of anatomy, and some thought they were important for discussing bioethics concepts. However, 62.5% felt that there were valid reasons for their discontinuation. Half of the respondents did not consider the continued use of eponyms an ethical concern. Responding editors of anatomical journals prefer the use of Latin- and Greek- derived terms when interacting with other anatomists and students. However, the continued use of eponyms was seen as an important opportunity for discussion on the history and ethics of anatomy.
Prevalence of Tetranychus urticae Koch and T. turkestani (Ugarov & Nikolskii) (Acari: Tetranychidae) and their endosymbiotic bacteria in cotton fields of Aydin, Türkiye
Authors: Yüksel Fettah Çağrı , Özyılmaz Ümit , Mahdavi Sayed Mosayeb , Kazak Cengiz , Ay Recep , Çevik Bayram , Saboori Alireza , Cakmak Ibrahim 
Published: July 2024

AbstractSpider mites are important pests of cotton, a vital fiber crop cultivated in sun-drenched regions. This study investigated the prevalence and distribution of spider mite species infesting cotton fields in Aydin province, Türkiye. Spider mites were found in a significant portion (89%) of the surveyed fields. The two most abundant mite species, were the red form (RF) of Tetranychus urticae (57.1%) and T. turkestani (39.3%). A minor presence of T. urticae green form (GF) (3.6%) was observed. Tetranychus urticae RF was more prevalent in coastal areas, while T. turkestani was more common inland. Field surveys demonstrated that areas with higher T. urticae RF prevalence exhibited more frequent spraying, potentially due to this species’ greater capacity to develop resistance compared to T. turkestani. This study also investigated the prevalence of Wolbachia, Rickettsia, Cardinium and Spiroplasma endosymbionts, which are linked with pesticide resistance due to their ability to degrade pesticides, in these mite populations. The study confirmed the presence of Wolbachia and Rickettsia endosymbionts in spider mite populations in Türkiye. However, no Cardinium or Spiroplasma were detected in any of the populations. Infection rates of the detected endosymbionts differed between T. urticae and T. turkestani. Future studies should investigate the resistance levels of these tetranychid mite species as well as the role of their endosymbiotic bacteria in resistance in cotton-growing areas.
Mindful Non-Judging and Posttraumatic Reactions in Police Academy Cadets: A Path Analysis
Authors: Chopko Brian A. , Adams Richard E. , Davis Jeremy , Pelger Terri L. , Palmieri Patrick A. 
Published: July 2024

Abstract
Objectives
Dispositional mindfulness has been associated with lower posttraumatic stress disorder (PTSD) and other negative health symptoms in the police population. Of the various mindfulness facets (i.e., non-judging, observing, describing, acting with awareness), non-judging has been demonstrated to be the strongest predictor of lower PTSD symptoms in police academy cadets. The mechanisms by which non-judging may lead to enhanced health outcomes in police officers are poorly understood and require further investigation.

Method
The purpose of the current study was to test a model involving a pathway from pre-trauma mindful non-judging to PTSD symptoms and ultimately posttraumatic growth (PTG) that is mediated by worldviews in a sample of police academy cadets (n = 379). Data were collected via a survey packet distributed at a police academy located in a Southern state of the United States. We examined the relationships among demographic factors, adverse child events, negative life events, mindful non-judgment, world assumptions, PTSD, and PTG using path analysis.

Results
The results indicated that positive worldviews served as a mediator between dispositional mindful non-judging and lower PTSD symptoms, which ultimately led to lower PTG.

Conclusions
These findings have important implications for the selection and training of police academy cadets with the goal of increasing resilience to occupational trauma exposure. Additionally, these results have clinical implications regarding the treatment of officers experiencing symptoms of PTSD.

Preregistration
This study is not preregistered.