bluuebunny/crossref_metadata_2025_split huggingface dataset:
One-to-one peer-coaching for patients with cancer — results of a pilot study
Authors: Valjanow Alice , Weis Joachim 
Published: August 2024

Abstract
Purpose
Cancer is a life threatening disease with negative impact on quality of life and psychological well-being. In international studies, one-to-one peer support and counseling have been shown to improve the psychological well-being of cancer patients. In the study presented, we developed and evaluated an innovative program of peer-coaching. In this program at the University Hospital of Freiburg, cancer survivors were trained to support peers by sharing experience.

Methods
In the project, N = 25 cancer survivors were trained to conduct supportive one-to-one conversations with acute patients or patients in aftercare. Based on a prospective observational study, patients were interviewed using questionnaires before and after the conversations. We assessed expectations and experiences with the peer-coaching as well as psychosocial parameters (PHQ9, GAD7, SSUK, NCCN-distress thermometer).

Results
A total of 52 patients had at least one contact with a peer-coach. Most of the patients attended 1–3 sessions. In total, 85 contacts pairing peer-coaches with patients were conducted. Patients showed on average a high level of distress but a low rate of psychiatric comorbidity. The supportive conversations met the patients` needs. Sharing experiences and empowerment were the most relevant benefits for the patients. Both patients and trained peers showed high satisfaction levels with the program.

Conclusion
Our findings support the feasibility and utility of a peer-coaching program in which trained cancer survivors, acting as peer-coaches, support other patients during or after their oncological treatment. In a further study, the efficacy of peer-coaching should be investigated based on a randomized-controlled trial.

Trial registration
The trial was registered in the German Clinical Trials Register (No. DRKS DRKS00017500) on 12.12.2019.
Outcome of gastric electrical stimulator with and without pyloromyotomy for refractory gastroparesis
Authors: Aeschbacher Pauline , Garcia Angelica , Dourado Justin , Rogers Peter , Zoe Garoufalia , Pena Ana , Szomstein Samuel , Menzo Emanuele Lo , Rosenthal Raul 
Published: August 2024

Abstract
Background
Surgical treatments of refractory gastroparesis include pyloromyotomy and gastric electrical stimulator (GES). It is unclear if patients may benefit from a combined approach with concomitant GES and pyloromyotomy.

Methods
Retrospective cohort analysis of all patients with refractory gastroparesis treated with GES implantation with and without concomitant pyloromyotomy at Cleveland Clinic Florida from January 2003 to January 2023. Primary endpoint was efficacy (clinical response duration and success rate) and secondary endpoints included safety (postoperative morbidity) and length of stay. Success rate was defined as the absence of one of the following reinterventions during follow-up: Roux-en-Y gastric bypass (RYGB), pyloromyotomy, GES removal.

Results
During a period of 20 years, 134 patients were treated with GES implantation. Three patients with history of previous surgical pyloromyotomy or RYGB were excluded from the analysis. Median follow-up was 31 months (IQR 10, 72). Forty patients (30.5%) had GES with pyloromyotomy, whereas 91 (69.5%) did not have pyloromyotomy. Most of the patients had idiopathic (n = 68, 51.9%) or diabetic (n = 58, 43.3%) gastroparesis. Except for preoperative use of opioids (47.5 vs 14.3%; p < 0.001), patient’s characteristics were similar in both groups. There were no significant differences between the two groups in terms of overall postoperative complications (17.5% vs 14.3%; p = 0.610), major postoperative complications (0% vs 2.2%; p = 1), and length of stay (2(IQR 1, 2) vs 2(IQR 1, 3) days; p = 0.068). At 5 years, success rate was higher in patients with than without pyloromyotomy however not statistically significant (82% versus 62%, p = 0.066). Especially patients with diabetic gastroparesis seemed to benefit from pyloromyotomy during GES (100% versus 67%, p = 0.053). In an adjusted Cox regression, GES implantation without pyloromyotomy was associated with a 2.66 times higher risk of treatment failure compared to GES implantation with pyloromyotomy (HR 2.66, 95% CI 1.03–6.94, p = 0.044).

Conclusion
Pyloromyotomy during GES implantation for gastroparesis seems to be associated with a longer clinical response with similar postoperative morbidity and length of hospital stay than GES without pyloromyotomy. Patient with diabetic gastroparesis might benefit from a combination of GES implantation and pyloromyotomy.
Da Vinci single-port robotic system current application and future perspective in general surgery: A scoping review
Authors: Celotto Francesco , Ramacciotti Niccolò , Mangano Alberto , Danieli Giacomo , Pinto Federico , Lopez Paula , Ducas Alvaro , Cassiani Jessica , Morelli Luca , Spolverato Gaya , Bianco Francesco Maria 
Published: August 2024

Abstract
Background
The da Vinci Single-Port Robot System (DVSP) allows three robotic instruments and an articulated scope to be inserted through a single small incision. It received FDA approval in 2014 and was first introduced in 2018. The aim of this new system was to overcome the limitations of single-incision laparoscopic and robotic surgery. Since then, it has been approved for use only for urologic and transoral surgeries in some countries. It has been used as part of experimental protocols in general surgery.

Objective
By obtaining the CE mark at the end of January 2024, DVSP will soon enter the European market. This review aims to comprehensively describe the applications of DVSP in general surgery.

Design
A search of PubMed, Embase, and Ebsco databases up to March 2024 was conducted, with registration in PROSPERO (CRD42024536430), following the preferred reporting items for Systematic reviews and Meta-analyses for scoping review (PRISMA-Scr) guidelines. All the studies about the use of DVSP in general surgery were included.

Results
Fifty-six studies were included. The following surgical areas of use were identified: transabdominal and transanal colorectal, cholecystectomy, abdominal wall repair, upper gastroesophageal tract, liver, pancreas, breast, and thyroid surgery. The reported surgical and short-term outcomes are promising; a wide range of procedures have been performed safely. Some groups have found advantages, such as faster discharge, shorter operative time, and less postoperative pain compared to multiport robotic surgery.

Conclusion
Five years after its initial clinical applications, the use of the DVSP in general surgery procedures has demonstrated feasibility and safety. Hernia repair, cholecystectomy, and colorectal surgery emerge as the most frequently conducted interventions with this robotic system. Nevertheless, there is anticipation for further studies with larger sample sizes and extended follow-up periods to provide more comprehensive insights and data on the long-term outcomes, including the incidence of incisional hernia.

Graphical Abstract
Prognostic factors for pediatric patients with severe intestinal motility disorders: a single institution’s experience
Authors: Yano Keisuke , Muto Mitsuru , Sugita Koshiro , Murakami Masakazu , Onishi Shun , Harumatsu Toshio , Iwamoto Yumiko , Ogata Masato , Takada Lynne , Nishida Nanako , Kedoin Chihiro , Nagano Ayaka , Matsui Mayu , Yamada Koji , Yamada Waka , Matsukubo Makoto , Kawano Takafumi , Kaji Tatsuru , Ieiri Satoshi 
Published: August 2024

Abstract

Purpose
To identify the prognostic factors for pediatric severe intestinal motility disorder (IMD).

Methods
We reviewed the medical records of patients with severe IMD, who required total parenteral nutrition (TPN) for ≥ 60 days at our institution between April, 1984 and March, 2023, examining their characteristics to identify prognostic factors.

Results
The types of IMD in the 14 patients enrolled in this study were as follows: isolated hypoganglionosis (IHG, n = 6), extensive aganglionosis (EAG: n = 6), and chronic idiopathic intestinal pseudo-obstruction (CIIP, n = 2). There was no significant difference in mortality among the three types of severe IMD. Weaning-off TPN and the use of the colon were not significant prognostic factors, but cholestasis was a significant prognostic factor (p = 0.005). There was a high mortality rate (50%), with the major causes of death being intestinal failure-associated liver disease (IFALD) following hepatic failure, and catheter-related blood stream infection (CRBSI). One IHG patient underwent small bowel transplantation but died of acute rejection.

Conclusion
Severe IMD is still associated with a high mortality rate and cholestasis predicts the prognosis. Thus, preventing or improving IFALD and CRBSI caused by long-term TPN is important for reducing the mortality rate.
Acceptance of psychosocial bridging measures in context of dementia
Authors: Leicher Barbara , Buschert Verena , Benninghoff Jens , Scherbaum Norbert 
Published: August 2024

AbstractParticipants from an outpatient treatment program for cognitive disorders have been offered bridging measures because of limited access to the outpatient clinic during a Covid-19-caused lock-down. The aim of this study was to assess perceived stress, acceptance, and appreciation of the measures among patients and their caregivers compared to the previous bridging measure. Forty participants were offered treatment in person or online depending on their cognitive performance level. To evaluate acceptance, data collected from clinical routine was incorporated into a treatment observation. The evaluation of bridging measures by 25 participants was positive. Perceived stress was moderate to high among participants and has increased significantly compared to previous special treatment. Perceived stress in older patients had increased over the course of the pandemic. Bridging measures represented a treatment alternative and may offer previously untapped potential for location-independent psychosocial treatments in order to ameliorate both the patients’ and their caregivers’ convenience.
Unraveling the molecular complexity: Wtap/Ythdf1 and Lcn2 in novel traumatic brain injury secondary injury mechanisms
Authors: Ma Chaobang , Gou Caili , Sun Shiyu , Wang Junmin , Wei Xin , Xing Fei , Xing Na , Yuan Jingjing , Wang Zhongyu 
Published: August 2024

AbstractThe primary aim of this research was to explore the functions of Wtap and Ythdf1 in regulating neuronal Lipocalin-2 (Lcn2) through m6A modification in traumatic brain injury (TBI). By employing transcriptome sequencing and enrichment analysis, we identified the Wtap/Ythdf1-mediated Lcn2 m6A modification pathway as crucial in TBI. In our in vitro experiments using primary cortical neurons, knockout of Wtap and Ythdf1 led to the inhibition of Lcn2 m6A modification, resulting in reduced neuronal death and inflammation. Furthermore, overexpression of Lcn2 in cortical neurons induced the activation of reactive astrocytes and M1-like microglial cells, causing neuronal apoptosis. In vivo experiments confirmed the activation of reactive astrocytes and microglial cells in TBI and importantly demonstrated that Wtap knockdown improved neuroinflammation and functional impairment. These findings underscore the significance of Wtap/Ythdf1-mediated Lcn2 regulation in TBI secondary injury and suggest potential therapeutic implications for combating TBI-induced neuroinflammation and neuronal damage.
Incorporating aquatic biodiversity into sustainability index for hydrographic sub-basins: a multi-criteria stakeholder assessment approach in the Upper Paraná River
Authors: Tomadon Leonardo da Silva , do Couto Edivando Vitor , Bailly Dayani , Ferreira Jóse Hilário Delconte , de Vries Walter Timo , Agostinho Angelo Antonio 
Published: August 2024

AbstractSustainable development assessments in hydrographic sub-basins are powerful tools used to guide stakeholders. However, there remains a gap in incorporating new indicators (e.g., biodiversity indicators) into sustainability indexes, which have generally underestimated the environmental dimension. We propose an update to these indexes by incorporating biodiversity data on hydrographic sub-basins. Our goal was to introduce a new ecological sustainability index for hydrographic sub-basins (ESI-sb) that utilizes aquatic ecological indicators. We selected 16 indicators and aggregated them into four sustainability dimensions: economic, social, eco-environmental and negative environmental. We used a multi-criteria analysis based on the analysis hierarchy process (AHP) method to catch stakeholders' importance level of each indicator. The ESI-sb was calculated using the weighted average between the sub-indexes that represent the dimensions. Finally, we applied Gi* statistics to identify the ecological sustainability hotspots and coldspots regions, and the results showed in the Serra do Mar region, the southern region, and the Federal District had high ecological sustainability values; meanwhile, the hydrographic sub-basins that formed the coldspot clusters were located in the western region of the Upper Paraná River basin. The incorporation of aquatic biodiversity data into the index represents an innovation in sustainability indexes recently proposed to hydrographic sub-basins.
Graphical abstract
Stable isotope analysis reveals fish juveniles as a temporal main resource consumed by invasive pumpkinseed (Lepomis gibbosus)
Authors: Hnilička Michal , Janáč Michal , Palupová Eva , Tkachenko Maria Yu. , Horká Petra , Jandová Kateřina , Holubová Kateřina , Jurajda Pavel , Ondračková Markéta 
Published: August 2024

AbstractThe pumpkinseed Lepomis gibbosus (Linnaeus, 1758) is a small centrarchid fish species from North America that has invaded most European basins, with pronounced expected impacts. Analyses of pumpkinseed diet in its invasive range using gut content analysis (GCA) show macrozoobenthos as the most common dietary item, suggesting a competitive effect on native fish communities. Our study uses a combination of GCA and stable isotope analysis (SIA) to document pumpkinseed diet at two sites in its invaded range and relates pumpkinseed diet preferences with parasitic load. SIA revealed juvenile fish as a major prey item at one of the sites (63 and 50% of the diet of small and the large fish), while GCA showed pumpkinseed preying mostly on macroinvertebrates (chironomids, gastropods, Ephemeroptera, and Zygoptera larvae) at both sites. While infrequent infection by trophically transmitted parasitic nematodes could be related to low consumption of zooplankton, substantial infection by metacercariae of Posthodiplostomum centrarchi Hoffman1958 appears to reflect relatively high consumption rates of its intermediate host, physid snails. Using SIA allowed to demonstrate that pumpkinseed feeding in its non-native range can be based on piscivory, emphasising the need for combining multiple methods when studying the impact of non-native species on food webs.
Impact of Inter and Intra Organizational Factors in Healthcare Digitalization: a Conditional Mediation Analysis
Authors: Pattanaik Prasanta Kumar , Gupta Shivam , Pani Ashis K. , Himanshu Urmii , Pappas Ilias O. 
Published: August 2024

AbstractDigitalization of the healthcare industry is a major trend and focus worldwide. It has the capability to improve the quality of care, reduce costs, and increase accessibility. India’s Healthcare Vision 2030 serves as a driving force compelling healthcare organization in India to embrace digitalization in their operations and services. We surveyed Indian healthcare employees to provide a comprehensive understanding of how external factors impact an organization's internal resources towards successful adoption of healthcare digitalization. The integration of three theoretical perspectives Institutional Theory (IP), Resource-Based View (RBV), and Absorptive Capacity Theory (ACT)) enables a more holistic and intricacies view. Our results emphasize that healthcare digital transformation requires more than just investment and time. Neglecting to respond to external pressures can lead to limited outcomes in digitalization efforts. It necessitates the presence of an appropriate organizational culture, accompanied by strong belief and support from top management.
Approximating the probabilistic p-Center problem under pressure
Authors: Demange Marc , Haddad Marcel A. , Murat Cécile 
Published: August 2024

AbstractThe Probabilistic p-Center problem under Pressure (p) is a variant of the usual p problem we recently introduced in the context of wildfire management. The problem is to locate p shelters minimizing the maximum distance people will have to cover in case of fire in order to reach the closest accessible shelter. The landscape is divided into zones and is modeled as an edge-weighted graph with vertices corresponding to zones and edges corresponding to direct connections between two adjacent zones. The risk associated with fire outbreaks is modeled using a finite set of fire scenarios. Each scenario corresponds to a fire outbreak on a single zone (i.e., on a vertex) with the main consequence of modifying evacuation paths in two ways. First, an evacuation path cannot pass through the vertex on fire. Second, the fact that someone close to the fire may not take rational decisions when selecting a direction to escape is modeled using new kinds of evacuation paths. In this paper, we characterize the set of feasible solutions of p-instance. Then, we propose some approximation results for p. These results require approximation results for two variants of the (deterministic) p problem called p and p.
Global Existence for Long Wave Hopf Unstable Spatially Extended Systems with a Conservation Law
Authors: Gauss Nicole , Logioti Anna , Schneider Guido , Zimmermann Dominik 
Published: August 2024

AbstractWe are interested in reaction–diffusion systems, with a conservation law, exhibiting a Hopf bifurcation at the spatial wave number $$ k = 0 $$

k
=
0

. With the help of a multiple scaling perturbation ansatz a Ginzburg–Landau equation coupled to a scalar conservation law can be derived as an amplitude system for the approximate description of the dynamics of the original reaction–diffusion system near the first instability. We use the amplitude system to show the global existence of all solutions starting in a small neighborhood of the weakly unstable ground state for original systems posed on a large spatial interval with periodic boundary conditions.
The Role of Cultural Heterogeneity in Strengthening the Link Between Family Relationships and Life Satisfaction in 50 Societies
Authors: Li Liman Man Wai , Lun Vivian Miu-Chi , Bond Michael Harris , Yeung June Chun , Igou Eric Raymond , Haas Brian W. , Stoyanova Stanislava , Maricchiolo Fridanna , Zelenski John M. , Vauclair Christin-Melanie , Uchida Yukiko , Poláčková Šolcová Iva , Sirlopú David , Park Joonha , Kosiarczyk Aleksandra , Kocimska-Zych Agata , Capaldi Colin A. , Adamovic Mladen , Akotia Charity S. , Albert Isabelle , Appoh Lily , Arevalo Douglas , Baltin Arno , Denoux Patrick , Domínguez-Espinosa Alejandra , Esteves Carla Sofia , Gamsakhurdia Vladimer , Fülöp Márta , Garðarsdóttir Ragna B. , Gavreliuc Alin , Boer Diana , Igbokwe David O. , Işık İdil , Kascakova Natalia , Klůzová Kračmárová Lucie , Kostoula Olga , Kronberger Nicole , Kwiatkowska Anna , Lee J. Hannah , Liu Xinhui , Łużniak-Piecha Magdalena , Malyonova Arina , Barrientos Marroquin Pablo Eduardo , Mohorić Tamara , Mosca Oriana , Murdock Elke , Mustaffa Nur Fariza , Nader Martin , Nadi Azar , Okvitawanli Ayu , van Osch Yvette , Pavlopoulos Vassilis , Pavlović Zoran , Rizwan Muhammad , Romashov Vladyslav , Røysamb Espen , Sargautyte Ruta , Schwarz Beate , Selim Heyla A. , Serdarevich Ursula , Stogianni Maria , Sun Chien-Ru , Teyssier Julien , van Tilburg Wijnand A. P. , Torres Claudio , Vignoles Vivian L. , Xing Cai , Krys Kuba 
Published: August 2024

AbstractWe argue that the importance of family relationships for individual well-being varies across societies as a function of a society’s degree of cultural heterogeneity. To examine the role of family relationships, we analyzed the responses from 13,009 participants in 50 societies on their life satisfaction across societies varying in their levels of historical and contemporary cultural heterogeneity. Such heterogeneity creates differences in the frequency of interacting with unfamiliar groups, which leads families to become more central to their members’ satisfaction with life. Multi-level analyses showed that historical and contemporary cultural heterogeneity moderated the pattern such that greater historical or contemporary cultural heterogeneity of society promoted a stronger positive relation between family relationship satisfaction and individual life satisfaction. Our results also revealed that the moderating role of historical cultural heterogeneity was more reliable than that of contemporary cultural heterogeneity. These findings demonstrate the importance of societal demography in shaping people’s psychological processes in different historical periods, suggesting a universal, trans-historical cultural process.
Generalized double affine Hecke algebra for double torus
Authors: Hikami Kazuhiro 
Published: August 2024

AbstractWe propose a generalization of the double affine Hecke algebra of type-$$C^\vee C_1$$

C
∨

C
1

at specific parameters by introducing a “Heegaard dual” of the Hecke operators. Shown is a relationship with the skein algebra on double torus. We give automorphisms of the algebra associated with the Dehn twists on the double torus.
A novel image denoising technique with Caputo type space–time fractional operators
Authors: Tanriover Evren , Kiris Ahmet , Tunga Burcu , Tunga M. Alper 
Published: August 2024

AbstractA novel image denoising model, namely Full Fractional Total Variation (TVFF), based on the Rudin-Osher-Fatemi (ROF) and the fractional total variation models is presented. The leading advantage of TVFF model is that it uses fractional derivatives with length scale parameters instead of ordinary derivatives with respect to both time and spatial variables in the diffusion equation. The Riesz–Caputo fractional derivative operator is used to disperse nonlocal influence throughout all directions, whereas the Caputo fractional derivative concept is employed for time fractional derivatives. Therefore, the influence of neighboring pixels is given greater weight compared to those situated farther away and this reflects the consideration behind denoising process better. Moreover, the numerical approach is constructed, and its stability and convergence properties are thoroughly examined. To show the superiority of our model, the denoised images are subjected to visual and numerical comparisons using metrics such as the Signal-to-Noise Ratio (SNR), the Structural Similarity Index Measure (SSIM) and the Edge-Retention Ratio (ERR). The performance of the TVFF method is evaluated under various types of noise, including Poisson, Speckle, and Salt & Pepper, and the results are compared with those obtained using Gauss and Median Filters. Furthermore, the proposed method is applied to both blind and synthetic images, thereby showcasing its versatility and applicability across diverse datasets. The outcomes showcase the substantial potential of our enhanced model as a versatile and efficient tool for image denoising.