bluuebunny/crossref_metadata_2025_split huggingface dataset:
L'office de la Conception composé par Jean de Ségovie au Concile de Bâle
Authors: Ricossa Luca 
Published: October 2012

Le Concile de Bâle a été un des évènements historiques les plus importants du xve siècle. Dans le sillon du Grand Schisme d'Occident, il est plutôt connu pour ses idées révolutionnaires concernant la structure de l'Église et le schisme éphémère qu'elles ont entraîné. Sa définition du dogme de l'Immaculée Conception, plusieurs siècles avant celle de Pie IX, est toutefois moins connue, tout comme la personnalité du théologien Jean de Ségovie, une des figures marquantes du Concile. Militant pour les doctrines conciliaristes, il s'est battu aussi et, pourrait-on dire, surtout en faveur de l'Immaculée. Après la définition de 1439 il fut chargé par les pères conciliaires de rédiger un nouvel office liturgique pour la fête. Son travail nous offre un office liturgique complet, un des sommets de l'art musical médiéval. Sa monodie explore tous les chemins de la théorie modale de son temps pour nous donner une réalisation sonore extraordinaire des textes patristiques et dogmatiques choisis comme sources pour les antiennes et les répons où la pureté des lignes mélodiques s'allie à l'expressivité et à la représentation symbolique et rhétorique des textes.
A TLR5 Agonist Enhances CD8+ T Cell-Mediated Graft-versus-Tumor Effect without Exacerbating Graft-versus-Host Disease
Authors: Ding Xilai , Bian Guanglin , Leigh Nicholas D. , Qiu Jingxin , McCarthy Philip L. , Liu Hong , Aygun-Sunar Semra , Burdelya Lyudmila G. , Gudkov Andrei V. , Cao Xuefang 
Published: October 2012

Abstract
Allogeneic hematopoietic cell transplantation is an established treatment for hematologic and nonhematologic malignancies. Donor-derived immune cells can identify and attack host tumor cells, producing a graft-versus-tumor (GVT) effect that is crucial to the effectiveness of the transplantation therapy. CBLB502 is a novel agonist for TLR5 derived from Salmonella flagellin. On the basis of TLR5-mediated immunomodulatory function, we examined the effect of CBLB502 on GVT activity. Using two tumor models that do not express TLR5, and thereby do not directly respond to CBLB502, we found that CBLB502 treatment significantly enhanced allogeneic CD8+ T cell-mediated GVT activity, which was evidenced by decreased tumor burden and improved host survival. Importantly, histopathologic analyses showed that CBLB502 treatment did not exacerbate the moderate graft-versus-host disease condition caused by the allogeneic CD8+ T cells. Moreover, mechanistic analyses showed that CBLB502 stimulates CD8+ T cell proliferation and enhances their tumor killing activity mainly indirectly through a mechanism that involves the IL-12 signaling pathway and the CD11c+ and CD11b+ populations in the bone marrow cells. This study demonstrates a new beneficial effect of CBLB502, and suggests that TLR5-mediated immune modulation may be a promising approach to improve GVT immunity without exacerbating graft-versus-host disease.
N-Acetylcysteine Lock Solution Prevents Catheter-Associated Bacteremia in Rabbits
Authors: Aslam Saima , Jenne Keith , Reed Sharon , Ghannoum Mahmoud , Mehta Ravindra , Darouiche Rabih 
Published: October 2012

Purpose Indwelling vascular catheters are the most common cause of nosocomial bloodstream infections. One approach to infection prevention is the use of antimicrobial catheter lock solutions, although their widespread use is limited due to concern regarding the emergence of antimicrobial resistance. The primary purpose of this study was to determine the efficacy of N-acetylcysteine (NAC) lock solution in preventing peripheral bacteremia using an in vivo model of catheter-associated infection. Methods Twenty-four hours after inoculating a clinical isolate of Staphylococcus aureus into the lumen of tunneled external jugular catheters in rabbits, a catheter lock solution that contained NAC vs. heparinized saline alone was allowed to dwell for two consecutive periods of 72 hours. Surveillance peripheral and centrally collected blood cultures were obtained. Distal intravascular segments of the catheters were removed at day 7 and cultured using a sonication method. Results At 7 days after catheter insertion, none of the NAC-treated rabbits (0/8) developed peripheral bacteremia with S. aureus whereas 4/7 controls did (p=0.026). The bacterial yield from catheter tip cultures was not statistically different between the two arms. Conclusions These promising data encourage further clinical evaluation of an NAC lock solution for prevention of catheter-associated bacteremia in patients.
Feasibility of Short-Term Infusion of Magnesium Sulfate in Pediatric Patients With Status Asthmaticus
Authors: Irazuzta Jose , Egelund Tosha , Wassil Sarah K. , Hampp Christian 
Published: October 2012

OBJECTIVE
This report describes the feasibility of high-dose magnesium sulfate infusion in pediatric patients with status asthmaticus.

METHODS
Retrospective chart review over a 3-year period of all patients younger than 18 years of age with status asthmaticus who underwent a high-dose magnesium sulfate infusion for 4 hours. All patients were breathing spontaneously but were refractory to conventional therapy. The magnesium sulfate infusion regimen was 50 mg/kg (for patients weighing &gt;30 kg) or 75 mg/kg (for those weighing ≤30 kg) over a period of 30 to 45 minutes, followed by a continuous infusion of 40 mg/kg/hr for 4 hours. Information regarding vital and clinical respiratory signs, serum magnesium (SrMg), ionized magnesium (iMg), electrocardiograms, and cardiac troponin levels were retrieved. We analyzed the relationship between SrMg and iMg by using linear regression analysis.

RESULTS
Nineteen patients were included. At the end of the infusion, SrMg levels were 4.4 ± 0.8 mg/dL, and iMg levels were 0.95 ± 0.2 mmol/L. SrMg levels only moderately predicted iMg (r2 = 0.541). There were no reports of hypotension, respiratory failure, neurological problems, or nausea. Discomfort at the site of infusion was reported in three cases. Troponin levels (n = 12) and electrocardiograms (n = 12), when available, were noted at the end of the infusion and were normal in all patients p=0.01.

CONCLUSIONS
In this case series, short-term high-dose administration of magnesium sulfate in the context of status asthmaticus was feasible, and we did not observe clinical complications with its use. Total SrMg was inadequate to reflect the active form of magnesium, iMg. The dose used achieved theoretical therapeutic levels of iMg.
Inappropriate Vancomycin Therapeutic Drug Monitoring in Hospitalized Pediatric Patients Increases Pediatric Trauma and Hospital Costs
Authors: Suryadevara Manika , Steidl Kelly E. , Probst Luke A. , Shaw Jana 
Published: October 2012

OBJECTIVESThe objective of this study was to measure the appropriateness of vancomycin monitoring in a pediatric tertiary care center and to evaluate the effectiveness of two interventions, autonomous pharmacy therapeutic drug monitoring and health care provider education, in reducing avoidable pediatric patient trauma and hospital cost.METHODSA retrospective chart review evaluating vancomycin therapeutic drug monitoring (TDM) in pediatric inpatients was performed before and after the introduction of an autonomous pharmacy TDM program and health care provider (HCP) education.RESULTSThirty-five patients were included in our study, prior to any intervention. Of these, 9% of patients had trough concentrations appropriately deferred. Of the total of 64 trough concentrations obtained, 94% were considered to be inappropriate. After the start of the autonomous pharmacy TDM program, of the 54 eligible patients (111 troughs), 9% had trough concentrations appropriately deferred, and 34% were inappropriate. In the 3-month period following the introduction of HCP education in combination with pharmacy TDM, we identified 27 eligible patients. Among those, 15% of the patients had trough concentrations appropriately deferred. Of the 43 trough concentrations obtained, only 9% were considered to be inappropriate. The combination of pharmacy TDM with HCP education decreased annualized hospital cost by 60%, from $13,080 to $5232.CONCLUSIONSInappropriate vancomycin TDM occurs commonly in our institution, resulting in unnecessary hospital cost and patient trauma. The combination of pharmacy TDM and HCP education significantly improved clinical practice; however, results were short-lived. Further interventions, such as computer based order entry, will likely be needed to reinforce and improve long-term TDM practice in pediatric patients.
Implementation of a Standardized Process for Ordering and Dispensing of High-Alert Emergency Medication Infusions
Authors: Polischuk Emily , Vetterly Carol G. , Crowley Kelli L. , Thompson Ann , Goff Jeff , Nguyen-Ha Phuong-Tan , Modery Christine 
Published: October 2012

OBJECTIVES
Pharmacies encounter challenges when ensuring safe, timely medication dispensing to patients in the pediatric intensive care unit, when high-alert medications are needed in emergent situations. Removal of these medications from nursing stock presented challenges to providing timely administration to critical patients. The project's purpose was to develop a new method for reducing dispensing time while improving patient safety in pediatric intensive care units.

METHODS
A committee of physicians, nurses, a clinical pharmacist, and pharmacy administration collaborated for process development. The process established a list of compounded, ready-to-use infusions stored in the pharmacy, immediately available for dispensing. The dispensing mechanism includes ordering and dispensing processes using an “Urgent Drip Request” form. Most frequently ordered infusions (dopamine, epinephrine, norepinephrine) were added to automated dispensing cabinets in critical care units in concentrations that could be safely infused centrally or peripherally.

RESULTS
During the initial 4 months, 71 “Urgent Drip Request” sheets were processed. Drug utilization evaluation demonstrated a dispensing time of less than 1 minute for drip medications leaving the pharmacy after the form was received. No sheets processed exceeded the institutional 30-minute turnaround time, nor were errors or delays documented. Limited turnaround time data existed preimplementation but was not robust enough for analysis. It was not ethically feasible to perform a head-to-head comparison with the previous method, as it might have resulted in delay of therapy and negative patient outcomes.

CONCLUSIONS
This program allows high-alert medication infusion availability in an expedited manner, removes potential for compounding errors at the bedside, and assures clean room preparation. This has improved pharmacy efficiency in provision of safe patient care to critically ill pediatric patients.
Happy end : l’héritage amérindien dans Rouge, mère et fils de Suzanne Jacob
Authors: Biron Michel 
Published: October 2012

Le refus de l’héritage amérindien fait partie des « fictions dominantes » dénoncées par Suzanne Jacob dans son essai La bulle d’encre. Elle en fait le thème central de son roman Rouge, mère et fils (2001) dont cet article analyse la composition (autour de la couleur rouge) et les principaux personnages : la mère Delphine, le fils Luc, le père Félix de même qu’un personnage extravagant, appelé le Trickster, par qui la mère et le fils retrouveront en fin de roman le fil de leur histoire, irriguée par le sang amérindien qui coule dans leurs veines. L’article met l’accent sur le changement de registre qui apparaît dans le dernier chapitre du roman, lequel délaisse le ton ironique employé jusque-là au profit d’une prose poétique et solennelle. En s’emparant d’un héritage détourné (celui du métissage amérindien refoulé par le discours identitaire québécois), le roman se voit lui-même détourné par cet héritage, au nom d’une demande de sens venue de l’extérieur du roman.
Surface Plasmon - Guided Mode strong coupling
Authors: Castanié A. , Felbacq D. , Guizal B. 
Published: October 2012

It is shown that it is possible to realize strong coupling between a surface plasmon and a guided mode in a layered structure. The dispersion relation of such a structure is obtained through the S-matrix algorithm combined with the Cauchy integral technique that allows for rigorous computations of complex poles. The strong coupling is demonstrated by the presence of an anticrossing in the dispersion diagram and simultaneously by the presence of a crossing in the loss diagram. The temporal characteristics of the different modes and the decay of the losses in the propagation of the hybridized surface plasmons are studied.
Consumer Utility Function: Initial Findings Through Lagrange Optimization Method
Authors: Paurom Ferdinand C. 
Published: October 2012

The main problem in utility theory or its variant theory of consumer choice is that consumer is assumed capable of rational choice; yet, such choice is incapable of translating itself into rational numbers. On this account the assumption of rational choice remains dubious. This paper utilized Lagrange optimization method to approximate consumer utility function measured in cardinal units. The utility function was derived from the US deflated annual per capita consumption of pork and beef (United States department of Agriculture, USDA, 1998). This paper demonstrates that when quantities of pork are consumed, given the price, in effect gives diminishing marginal levels of pork consumption in opposite monotonic direction with beef consumption. Changes in the level of consumption approximate cardinally the consumer utility function consistent with the properties of indifference curve and with the axioms of consumer rational choice. This paper has two objectives: 1) to provide further insights on the measurability of consumer utility, and 2) to provide basis for forecasting the demand for pork and beef. This paper concluded that Pork-beef substitution of US consumers is an exponential function which exhibits pattern of the textbook-defined indifference curve and has the features of negative slope, convexity and asymptote. The function is also consistent with the axioms of consumer rational choice. Keywords - consumer utility function, lagrange optimization method
Developing a GIS for Rural Villages in the Philippines
Authors: Tongco Alejandro F. 
Published: October 2012

This paper is an introduction to applying geographic information systems (GIS) technology specifically to rural villages in the Philippines. GIS is a relatively new and valuable tool in decision making that is useful in managing organizations and applicable in a wide range of disciplines including agriculture, public health, natural resource management, and local governance. Rural village governance, although well-established, has been largely untouched by GIS technology. This paper lays out steps to develop a GIS that is uniquely villagebased and home-grown. The ultimate goal is to empower villagers to set the direction and implementation of their own village’s development efforts. The steps discuss how to build an inexpensive GIS for rural villages with the help of a GIS expert-coach. Village participation, interest of GIS technician-trainees, and village financial capability are some important considerations in village GIS capability building. A simple GIS for an actual village is also hypothetically illustrated. Keywords - Geographic Information system, rural villages
Mapping of Elementary Educational Infrastructure in India: A State and District Level Analysis
Authors: Kumar Vipan , Kumar Naresh , Narula Sapna 
Published: October 2012

Education plays an important role in a country’s development process. Indian education system comprises the elementary, secondary and tertiary levels. Over two decades India registered a significant growth in the educational infrastructure at tertiary level of education but elementary and secondary levels of education are struggling with low accessibility of infrastructure and resources. This is affecting the quality of education particularly at elementary level of education which is responsible for growth in secondary and tertiary education. The assessment of infrastructure across the country is very difficult due to regional inequalities and economic diversities. This paper is an attempt to map accessibility of infrastructure at elementary level of education at district and state level in India. For mapping and analysis, advance computation techniques like GIS and contour mapping techniques are used. A novel technique and algorithm was developed to represent the data in various formats in the qualitative way; to the knowledge of the authors this novel representation of data is hitherto unreported in the open literature. Analysis confirms that there are regional inequalities in the accessibility of required infrastructure and in some states the situation is pathetic despite various government initiatives. Keywords - Elementary education, GIS, Mapping, Contours
Teacher’s Efficacy as Predictor of Self- Efficacy Among Students In Pakistan
Authors: Nabeel Tanzila , Zafar Huma 
Published: October 2012

The study examined the role of teachers’ self-efficacy as a predictor of general perceived self-efficacy among students. For this purpose, a sample of 300 teachers and 300 students was selected from different educational institutions of Pakistan. Teachers were categorized into two groups; experienced and inexperienced. To achieve the objectives of the study two instruments i.e.; Teachers’ self-efficacy Scale and General Self-efficacy Scale (GSES) were used. In addition short demographic sheets for the teachers and students were used indicating teachers’ institutional affiliation and experience, and students’ educational institutes, ages and gender. Part I of the study dealt with determining the psychometric properties of the scales and the pilot study and Part II consisted of the main study. Statistical analyses of the main study revealed a significant positive correlation between teachers’ self-efficacy and general self-efficacy among students. Experienced teachers showed more teachers’ self-efficacy as compared to inexperienced teachers. Overall mean scores of female students were comparatively higher on General self-efficacy scale as compared to the male students. Students belonging to the late adolescence showed more self-efficacy as compared to the students categorized as early adolescence group. Simple linear regression analyses suggested that teacher self-efficacy contribute positively to self-efficacy among students. Keywords - Teachers’ self-efficacy, General perceived self-efficacy
The Connection between Moral Commitments and Psychological Health
Authors: Azadboni Ramezan Mahdavi 
Published: October 2012

The significant role of moral values and moral commitments in human life is neglected neither by philosophers nor by psychologists. One of considerable points regarding the role and function of moral value concerns psychological function and achievement. This paper deals with the psychological role and function fulfilled by moral commitment. According to religious teachings psychological aspect of human life has connection with moral commitment. The writer attempts to explain how moral values and commitment could be related to psychological health. The discussion is confined to general understanding of moral values in all world religions but mostly the references are limited to Islamic teachings. Keywords - moral, value, function, psychology
Philippine Journal Accreditation Service (JAS) of the Commission on Higher Education: Ensuring Quality in Higher Education Publication Towards Internationalization
Authors: Padua Roberto N. 
Published: October 2012

The paper examines the Journal accreditation process adopted by the Philippine Commission on Higher Education andanalyses the results of the accreditation process for three years: 2009, 2010, and 2011. Results revealed that less than 10% of all journals submitted for accreditation through the CHED-JAS have marginally satisfied the criteria set by the review Board. The main observations made by the review Board on the journals which did not satisfy the accreditation criteria focused on the absence of a good refereeing system and the qualifications of the Editorial Boards. Keywords - Journal Accreditation process, internationalization of research, research journals
Predictors of Teachers’ Reading Skills in a Rural School District in Northeastern Mindanao Philippines
Authors: Albarillo Loveleah B. 
Published: October 2012

Reading is a problem for teachers in the Philippines. It becomes even more acute for teachers in rural areas. In Surigao del Sur (Northeastern Mindanao—Philippines), the problem is especially worrisome. I designed a study that determines the predictors of the reading skills of teachers in a rural school district. To analyze the data, I used the frequency weighted mean, Pearson Moment-Product Correlation Coefficient, and regression analysis. I also used a standardized reading test as the reading instrument. On top of that, I asked the teachers to build a personal profile with socio-demographic and pedagogical variables. I gathered the data through a questionnaire. The results confirm in Surigao del Sur what is known to be the state of reading habits of teachers in the Philippines. The quality of reading skills is low or poor. The teachers are not able to teach competently in language and reading. They have higher order skills in scanning and points of view. They have average levels of vocabulary. They use study aids infrequently. They have low levels of reading comprehension. Age is the most important predictor of reading skill. It tends to decline as teachers grow older. They read less the longer they stay in the service. It is specifically noticeable among teachers who do not exert the effort to deepen their professional studies. Teachers 40 and above need a special reading intervention. To prevent a decline in reading skill, all rural teachers ought to do graduate-level work. Keywords - socio-demographic variables, pedagogical variables, reading skills of teachers
The Effect of Constructivist Teaching Approach on the Conceptual Understanding of Biology Students
Authors: Ronsairo Marlyn D. 
Published: October 2012

This study determines the effect of constructivist-based teaching approach on the cognitive and affective levels of conceptual understanding of Marine Biology of BS Biology students. The study made use of the pre-test-posttest one-shot experimental design. The participants were selected using purposive sampling. Data and other information needed in this study were gathered mainly through conceptual understanding test, formal interviews and journals. And to treat these data, the mean scoring system and t-test for dependent samples were used. Results revealed that the extent of cognitive level of conceptual understanding in Marine Biology of the students based on their journals was observed to a very great extent. On the other hand, the extent of affective level of conceptual understanding of the students in Marine Biology as revealed in their journals was observed to a great extent. Moreover, the findings also showed that there is significant difference on the students’ level of conceptual understanding based on their mean scores in the test after using the constructivist-based teaching approach. Lastly, it is also found out that the students learned and appreciated Marine Biology through constructivist-based teaching approach based on the interviews conducted to them. Keywords - conceptual understanding, constructivist-based teaching approach