bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association of High Body Mass Index With Decreased Treatment Response to Combination Therapy in Recent‐Onset Rheumatoid Arthritis Patients
Authors: Heimans L. , van den Broek M. , le Cessie S. , Siegerink B. , Riyazi N. , Han K. H. , Kerstens P. J. S. M. , Huizinga T. W. J. , Lems W. F. , Allaart C. F. 
Published: February 2013

ObjectiveTo assess the association between high body mass index (BMI) and treatment response in recent‐onset rheumatoid arthritis.MethodsIn the Behandelstrategieën voor Reumatoide Artritis (Treatment Strategies for Rheumatoid Arthritis) study, 508 patients were randomized to initial monotherapy or combination therapy with prednisone or infliximab (IFX). The response to Disease Activity Score (DAS) ≤2.4–steered treatment (first dose and after 1 year) was compared between patients with a BMI <25 kg/m2 and ≥25 kg/m2, using relative risk (RR) regression analyses. DAS, components of DAS, and functional ability during the first year were compared using linear mixed models.ResultsHigh BMI was independently associated with failure to achieve a DAS ≤2.4 on initial therapy (RR 1.20 [95% confidence interval (95% CI) 1.05, 1.37]). The effect for combination therapy with prednisone was RR 1.55 (95% CI 1.06, 2.28) and for combination therapy with IFX 1.42 (95% CI 0.98, 2.06). The RRs for failure after 1 year were 1.46 (95% CI 0.75, 2.83) and 2.20 (95% CI 0.99, 4.92), respectively. High BMI was also associated with failure on delayed combination therapy with IFX, after adjustment for selection bias related to previous failure on disease‐modifying antirheumatic drugs. No significant association was observed in the initial monotherapy groups. In the first year, patients with a high BMI had higher DAS and worse functional ability, with more tender joints and a higher visual analog scale global health, but not more swollen joints and similar systemic inflammation.ConclusionHigh BMI was independently associated with failure to achieve low DAS on initial combination therapy with prednisone and on initial and delayed treatment with IFX. Patients with a high BMI experienced more pain, but not more swelling or systemic inflammation.
Interpretation of Optoelectronic Transient and Charge Extraction Measurements in Dye‐Sensitized Solar Cells
Authors: Barnes Piers R. F. , Miettunen Kati , Li Xiaoe , Anderson Assaf Y. , Bessho Takeru , Gratzel Michael , O'Regan Brian C. 
Published: February 2013

AbstractTools that assess the limitations of dye sensitized solar cells (DSSCs) made with new materials are critical for progress. Measuring the transient electrical signals (voltage or current) after optically perturbing a DSSC is an approach which can give information about electron concentration, transport and recombination. Here we describe the theory and practice of this class of optoelectronic measurements, illustrated with numerous examples. The measurements are interpreted with the multiple trapping continuum model which describes electrons in a semiconductor with an exponential distribution of trapping states. We review standard small perturbation photocurrent and photovoltage transients, and introduce the photovoltage time of flight measurement which allows the simultaneous derivation of both effective diffusion and recombination coefficients. We then consider the utility of large perturbation measurements such as charge extraction and the current interrupt technique for finding the internal charge and voltage within a device. Combining these measurements allows differences between DSSCs to be understood in terms such as electron collection efficiency, semiconductor conduction band edge shifts and recombination kinetics.
Rational Design of Advanced Thermoelectric Materials
Authors: Yang Jihui , Yip Hin‐Lap , Jen Alex K.‐Y. 
Published: February 2013

AbstractAdvanced thermoelectric technologies can drastically improve energy efficiencies of industrial infrastructures, solar cells, automobiles, aircrafts, etc. When a thermoelectric device is used as a solid‐state heat pump and/or as a power generator, its efficiency depends pivotally on three fundamental transport properties of materials, namely, the thermal conductivity, electrical conductivity, and thermopower. The development of advanced thermoelectric materials is very challenging because these transport properties are interrelated. This paper reviews the physical mechanisms that have led to recent material advances. Progresses in both inorganic and organic materials are summarized. While the majority of the contemporary effort has been focused on lowering the lattice thermal conductivity, the latest development in nanocomposites suggests that properly engineered interfaces are crucial for realizing the energy filtering effect and improving the power factor. We expect that the nanocomposite approach could be the focus of future materials breakthroughs.
Hospitalizations among people with Down syndrome: A nationwide population‐based study in Denmark
Authors: Zhu Jin Liang , Hasle Henrik , Correa Adolfo , Schendel Diana , Friedman J.M. , Olsen Jørn , Rasmussen Sonja A. 
Published: February 2013

AbstractMost persons with Down syndrome (DS) now survive to adulthood, but their health care needs beyond childhood are not well described. We followed a national cohort of 3,212 persons with DS and a reference cohort of persons without DS through the Danish National Hospital Register from January 1, 1977, to May 31, 2008. Poisson regression was used to calculate rate ratios for numbers of overnight hospital admissions and hospital days. During the study period, persons with DS had more than twice the rate of hospital admissions and nearly three times as many bed‐days as the population as a whole. Malformations, diseases of the respiratory system, and diseases of the nervous system or sensory organs were the principal indications for hospital admissions. The higher rate ratios for hospital admissions were seen especially among persons less than 20 years of age. Hospitalizations for neoplasms or for diseases of the musculoskeletal system or connective tissue were much less frequent among adults with DS. As survival among persons with DS continues to improve, these findings are likely to be useful for health care planning, although the potential utility may be different for different health care systems. © 2013 Wiley Periodicals, Inc.
Conformational dynamics of xylanase a from Streptomyces lividans: Implications for TIM‐barrel enzyme thermostability
Authors: Ding Yanrui , Cai Yujie 
Published: February 2013

ABSTRACTThe conformational dynamics of xylanase A from Streptomyces lividans (Sl‐XlnA) were studied using Molecular Dynamics (MD) simulation to identify the thermally sensitive regions. Sl‐XlnA begins to unfold at loop4 and this unfolding expands to the loops near the N‐terminus. The high flexibility of loop6 during the 300 K simulation is related to its function. The intense movements of the 310‐helices also affect the structural stability. The interaction between the α4β5‐loop and the neighboring α5β6‐loop plays a crucial role in stabilizing the region from the α4β5‐loop to α6. The most thermally sensitive region is from β3 to loop4. The high mobility of the long loop4 easily transfers to the adjacent β4 and α4 and causes β4 and α4 to fluctuate. And, salt bridges ASP124‐ARG79, ASP200‐ARG159, and ASP231‐LYS166 formed a “clamp” to stabilize the region including α4, β4, β5, β6, and β7. © 2013 Wiley Periodicals, Inc. Biopolymers 99: 594–604, 2013.
Japanese multicenter registry evaluating the retrograde approach for chronic coronary total occlusion
Authors: Tsuchikane Etsuo , Yamane Masahisa , Mutoh Makoto , Matsubara Tetsuo , Fujita Tsutomu , Nakamura Shigeru , Muramatsu Toshiya , Okamura Atsunori , Igarashi Yasumi , Oida Akitsugu ,   Retrograde Summit Investigators
Published: February 2013

ObjectivesThis registry evaluated the current trends and outcomes associated with retrograde percutaneous coronary intervention (PCI) for chronic total occlusion (CTO).BackgroundSince its introduction, several techniques and technologies have been introduced for retrograde PCI for CTO.MethodsEight hundred and one patients who underwent retrograde PCI for CTO in 28 Japanese centers between January 2009 and December 2010 were enrolled in this registry.ResultsOverall procedural and clinical success rates were 84.8 and 83.8%, respectively, of which, retrograde procedures accounted for 71.2 and 70.3%, respectively. The use of channel dilators increased in 2010 compared to that in 2009 (36 vs. 95.3%, P < 0.0001), attributed improving collateral channel crossing using a wire and catheter (70.6% vs. 81.1%, P = 0.0005) and increased availability of epicardial channels (27.6% vs. 36.9%). The use of the reverse controlled antegrade and retrograde tracking technique also increased (41.9 vs. 66.5%). Although these changes decreased procedure time (203.3 min vs. 187.9 min, P = 0.024), they did not significantly improve overall procedural success rate (84.1% vs. 85.3%, P = 0.63). Multivariate analysis identified age 65 years or more and lesion calcification as unfavorable factors and the use of a channel dilator as a favorable factor for retrograde procedural success.ConclusionsIncreased availability of channel dilators has altered strategies for retrograde PCI for CTO. However, retrograde PCI for CTO could be improved by overcoming its main obstacle of severe calcification. © 2013 Wiley Periodicals, Inc.
ChemInform Abstract: DFT+U Study of the Oxide‐Ion Conductor Pentalanthanum Hexamolybdenum Henicosaoxide
Authors: Goumri‐Said Souraya , Kanoun Mohammed Benali 
Published: February 2013

AbstractCalculations of the structural, elastic, electronic, magnetic and optical properties show that La5Mo6O21 is metallic with a high ionic character due to the oxygen composition.
ChemInform Abstract: Structural and Conductivity Studies of CsK(SO4)0.32(SeO4)0.68Te (OH)6.
Authors: Djemel M. , Abdelhedi M. , Zouari N. , Dammak M. , Kolsi A. W. 
Published: February 2013

AbstractSingle crystals of the title compound are prepared at room temperature by slow evaporation of a solution containing H6TeO6, cesium potassium sulfate, and cesium potassium selenate.
ChemInform Abstract: Unexpected Luminescence Properties of Sr0.25Ba0.75Si2O2N2 :Eu2+ — A Narrow Blue Emitting Oxonitridosilicate with Cation Ordering.
Authors: Seibald Markus , Rosenthal Tobias , Oeckler Oliver , Fahrnbauer Felix , Tuecks Andreas , Schmidt Peter J. , Schnick Wolfgang 
Published: February 2013

AbstractPowder samples of the title compound are prepared by reacting (Sr0.25Ba0.75) 2SiO4:Eu2+ with a stoichiometric amount of Si powder (95:5 N2/H2, 1350 °C, 5 h).
ChemInform Abstract: Electronic, Optical Properties and Chemical Bonding in Six Novel 1111‐Like Chalcogenide Fluorides AMChF (A: Sr, Ba; M: Cu, Ag; and Ch: S, Se, Te) from First Principles Calculations.
Authors: Bannikov V. V. , Shein I. R. , Ivanovskii A. L. 
Published: February 2013

AbstractThe compounds SrAgSF, SrAgSeF, SrAgTeF, BaAgSF, BaAgSeF, and SrCuTeF are characterized by first principles LAPW band structure calculations.
ChemInform Abstract: Ba1‐xNaxTi2Sb2O (0.0 ≤ x ≤ 0.33): A Layered Titanium‐Based Pnictide Oxide Superconductor.
Authors: Doan Phuong , Gooch Melissa , Tang Zhongjia , Lorenz Bernd , Moeller Angela , Tapp Joshua , Chu Paul C. W. , Guloy Arnold M. 
Published: February 2013

AbstractThe title compounds are synthesized from BaO, BaO2, Na2O, Ti, and Sb (Nb containers, 900 °C, 3 d) and characterized by powder XRD and electrical resistivity and magnetic measurements.
ChemInform Abstract: Perovskite B‐Site Compositional Control of [110]p Polar Displacement Coupling in an Ambient‐Pressure‐Stable Bismuth‐Based Ferroelectric.
Authors: Claridge John B. , et al. et al. 
Published: February 2013

AbstractA new lead‐free bismuth based perovskite, Bi0.72La0.28 (Fe0.46Ti0.27Mg0.27)O3, is prepared at ambient pressure by ball‐milling of mixtures of Bi2O3, La2O3, Fe2O3, TiO2, and 4MgCO3·Mg(OH)2·4H2O, followed by firing in air at 950 °C (14 h).
ChemInform Abstract: New Perspectives on Polyoxometalate Catalysts: Alcohol Oxidation with Zn/Sb‐Polyoxotungstates.
Authors: Ni Lubin , Patscheider Joerg , Baldridge Kim K. , Patzke Greta R. 
Published: February 2013

Abstract(NH4)10[Zn(H2O)6]2 [Zn2Sb2 (B‐α‐ZnW9O34)2] ·12H2O (I) is prepared prepared by reaction of Na9[SbW9O33] and Zn(OAc)2 (H2O, 85 °C, 90 min) followed by addition of excess NH4Cl at room temperature and slow evaporation of the solvent (10 d, 16% yield).
ChemInform Abstract: Syntheses, Crystal Structures, and Characterization of Two New Tl+—Cu2+—Te6+ Oxides: Tl4CuTeO6 and Tl6CuTe2O10.
Authors: Yeon Jeongho , Kim Sang‐Hwan , Green Mark A. , Bhatti Kanwal Preet , Leighton C. , Halasyamani P. Shiv 
Published: February 2013

AbstractCrystals of the title compounds are prepared by hydrothermal reaction of CuO, Tl2CO3, and TeO2 in aq.
ChemInform Abstract: Reactions of α‐Ylidene (Vinylidene, Benzylidene, Styrylmethylidene) Bis[carbonyls] with Copper Mono/Bis[carbonylcarbenoids].
Authors: Merey Goekce , Kaya Mustafa , Anac Olcay 
Published: February 2013

AbstractThe product distribution of the copper‐catalyzed reaction of various conjugated dicarbonyl compounds with either diazomalonate (II) or diazoacetate (XII) are studied (40 examples).
ChemInform Abstract: Copper‐Catalyzed Oxytrifluoromethylation of Unactivated Alkenes.
Authors: Zhu Rong , Buchwald Stephen L. 
Published: February 2013

AbstractCarboxylic acids, alcohols, and phenols bearing a terminal alkene moiety can serve as suitable nucleophiles for the title reaction with Togni′s trifluoromethylating reagent (II) to give trifluoromethyl containing lactones, cyclic ethers, and epoxides.
ChemInform Abstract: Oxime Radical Promoted Dioxygenation, Oxyamination, and Diamination of Alkenes: Synthesis of Isoxazolines and Cyclic Nitrones.
Authors: Han Bing , Yang Xiu‐Long , Fang Ran , Yu Wei , Wang Chao , Duan Xiao‐Yong , Liu Shuai 
Published: February 2013

AbstractBy using TEMPO or DEAD as the radical initiator, oxime radicals are generated from β,γ‐ or γ,δ‐unsaturated ketoximes to give 4,5‐dihydroisoxazoles and cyclic nitrones, respectively, through C—O and C—N bond forming 5‐exo‐trig cyclization reactions.
ChemInform Abstract: A Novel, Green 1‐Glycyl‐3‐methyl Imidazolium Chloride—Copper(II) Complex Catalyzed C—H Oxidation of Alkyl Benzene and Cyclohexane.
Authors: Karthikeyan Parasuraman , Bhagat Pundlik Rambhau , Kumar S. Senthil 
Published: February 2013

AbstractThe catalyst can be reused 7 times without significant loss of activity.
ChemInform Abstract: Synthesis of Ionic Liquid‐Supported Sulfonyl Azide and Its Application in Diazotransfer Reaction.
Authors: Muthyala Manoj Kumar , Choudhary Sunita , Kumar Anil 
Published: February 2013

AbstractThe new ionic liquid azide ILSA is found to be an efficient diazo‐transfer reagent which allows synthesis of a wide range of diazo compounds under mild, simple, and environmentally friendly conditions.
ChemInform Abstract: γ‐Amino Alcohols via Organocascade Reactions Involving Dienamine Catalysis.
Authors: Appayee Chandrakumar , Fraboni Americo J. , Brenner‐Moyer Stacey E. 
Published: February 2013

AbstractProlinol‐catalyzed reaction of enals with azadicarboxylates followed by treatment with Hantzsch ester and NaBH4 allows a new access to optically active γ‐amino alcohols.
ChemInform Abstract: Enantioselective Conjugate Addition of Donor—Acceptor Hydrazones to α,β‐Unsaturated Aldehydes Through Formal Diaza—Ene Reaction: Access to 1,4‐Dicarbonyl Compounds.
Authors: Fernandez Maitane , Uria Uxue , Vicario Jose L. , Reyes Efraim , Carrillo Luisa 
Published: February 2013

AbstractA new approach for the title reaction is developed under metal‐free conditions.
ChemInform Abstract: Selenium and Sulfur Dichlorides as Chlorinating Agents in the Reaction with Alkyl 2,2‐Dichlorovinyl Sulfides.
Authors: Martynov A. V. , Makhaeva N. A. , Amosova S. V. 
Published: February 2013

AbstractThe chlorination of dichlorovinyl sulfides (I) is performed by using selenium or sulfur dichloride in the presence of FeCl3 or AlCl3 as catalyst.
ChemInform Abstract: Conjugate Hydrocyanation of Aromatic Enones Using Potassium Hexacyanoferrate(II) as an Eco‐Friendly Cyanide Source.
Authors: Li Zheng , Liu Chenhui , Zhang Yupeng , Li Rongzhi , Ma Ben , Yang Jingya 
Published: February 2013

AbstractAn efficient one‐pot two‐step procedure involving initial formation of benzoyl cyanide is developed for the conjugate hydrocyanation of aromatic enones to give the corresponding β‐cyano ketones.
ChemInform Abstract: Metal‐Free Oxidative Trifluoromethylthiolation of Terminal Alkynes with CF3SiMe3 and Elemental Sulfur.
Authors: Chen Chao , Chu Lingling , Qing Feng‐Ling 
Published: February 2013

AbstractA variety of alkynyl trifluoromethyl sulfides are prepared by the title reaction (22 examples).
ChemInform Abstract: Convenient Synthesis of 2,2′‐ and 4,4′‐Methylenebisphenols with Bulky Alkyl Substituents and Evaluation of Their Antioxidant Activity.
Authors: Buravlev Evgeny V. , Chukicheva Irina Yu. , Borisenkov Mikhail F. , Kutchin Aleksandr V. 
Published: February 2013

AbstractAntioxidant activities of novel compounds, possessing an isobornyl fragment [cf.
ChemInform Abstract: Rhodium(III)‐Catalyzed Dehydrogenative Heck Reaction of Salicylaldehydes.
Authors: Shi Zhuangzhi , Schroeder Nils , Glorius Frank 
Published: February 2013

AbstractThe title reaction complements the Heck reaction on carbonyl substrates and provides substrates like aurones, e.g. (III), flavone (XVI), flavanone (XVII), and 2′‐hydroxychalcones, e.g. (XIV), from readily available starting materials.
ChemInform Abstract: Heterobimetallic Pd—Sn Catalysis: A Suzuki, Tandem Ring‐Closing Sequence Toward Indeno[2,1‐b]thiophenes and Indeno[2,1‐b]indoles.
Authors: Das Debjit , Pratihar Sanjay , Roy Sujit 
Published: February 2013

AbstractOnly electron‐rich arenes can be used as active nucleophiles.
ChemInform Abstract: Expeditious Microwave‐Assisted Synthesis of 5‐Alkoxyoxazoles from α‐Triflyloxy Esters and Nitriles.
Authors: Jouanno Laurie‐Anne , Sabot Cyrille , Renard Pierre‐Yves 
Published: February 2013

AbstractAn efficient and widely applicable method to prepare 5‐alkoxyoxazoles is given.
ChemInform Abstract: T3P®‐DMSO‐Mediated One‐Pot Cascade Protocol for the Synthesis of 4‐Thiazolidinones from Alcohols.
Authors: Kumar Kothanahally S. Sharath , Swaroop Toreshettahally R. , Harsha Kachigere B. , Narasimhamurthy Kereyagalahally H. , Rangappa Kanchugarakoppal S. 
Published: February 2013

AbstractThe mild protocol allows the preparation of various biologically interesting thiazole derivatives with a high functional group tolerance.
ChemInform Abstract: Copper‐Doped Silica Cuprous Sulfate (CDSCS) as a Highly Efficient and New Heterogeneous Nano Catalyst for [3 + 2] Huisgen Cycloaddition.
Authors: Rad Mohammad Navid Soltani , Behrouz Somayeh , Doroodmand Mohammad Mahdi , Movahediyan Abdollah 
Published: February 2013

AbstractNewly synthesized copper‐doped silica cuprous sulfate is used as an efficient catalyst in 1,3‐dipolar cycloaddition reactions of various acyclic β‐azido alcohols (I) with terminal alkynes.
ChemInform Abstract: Propylene Oxide Assisted One‐Pot, Tandem Synthesis of Substituted‐1,3,4‐oxadiazole‐2(3H)‐ones in Water.
Authors: Yan Xu , Zhou Shuo , Wang Yuanqiang , Ge Zemei , Cheng Tieming , Li Runtao 
Published: February 2013

AbstractTitle compounds (III) and (V) are synthesized by the present new reaction of different acylhydrazines (I) and (IV) with carbon disulfide (II) promoted by propylene oxide.
ChemInform Abstract: Reactions of 2‐(Trifluoromethyl)‐2‐hydroxy‐2H‐chromenes with Thiophenols Promoted by Lewis Acid.
Authors: Li Xinjin , Zhao Jingwei , Wang Zhongwei , Han Jianwei , Zhao Jian , Zhu Shizheng 
Published: February 2013

AbstractThe present new substitution reaction between chromene (I) and various thiophenols gives a mixture of 4‐thiophenylchromenes (III) and 2‐thiophenylchromenes (IV).
ChemInform Abstract: Nano‐SnCl4·SiO2 — A Versatile and Efficient Catalyst for Synthesis of 14‐Aryl‐ or 14‐Alkyl‐14H‐dibenzo[a,j]xanthenes
Authors: Mirjalili B. F. , Bamoniri A. , Mirhoseini M. A. 
Published: February 2013

Abstractfrom 2‐naphthol (I) and various aliphatic and aromatic aldehydes under solvent‐free reaction conditions
ChemInform Abstract: Improved Process for Paroxetine Hydrochloride Substantially Free from Potential Impurities.
Authors: Gangula Srinivas , Kolla Naveen Kumar , Elati Chandrasekar , Dongamanti Ashok , Bandichhor Rakeshwar 
Published: February 2013

AbstractSelected steps in the synthesis of the antidepressant drug paroxetine (IV) are optimized to control potential impurities and to meet ICH standards.
ChemInform Abstract: Enantioselectivity in Visible Light‐Induced, Singlet Oxygen [2 + 4] Cycloaddition Reactions (Type II Photooxygenations) of 2‐Pyridones.
Authors: Wiegand Christian , Herdtweck Eberhardt , Bach Thorsten 
Published: February 2013

Abstract3‐Substituted 2‐pyridones (I) and (III) are enantioselectively converted into the corresponding 3‐hydroxypyridine‐2,6‐diones (II) and (IV) by a sequence of a template‐mediated type II photooxygenation and an acid‐catalyzed rearrangement.
ChemInform Abstract: Novel and Efficient Synthesis of Substituted Quinoline‐1‐oxides and the Complex Compounds SnL2Cl2 (L = 2‐Aminoquinoline‐1‐oxides) with the Aid of Stannous Chloride.
Authors: Fu Lei , Lin Wei , Xu Pan , Xi Yu‐Kun , Wang Man‐Man , Shi Da‐Qing 
Published: February 2013

AbstractTreatment of nitrophenylacrylonitriles (I), bearing a nitrile or an ester group, with tin dichloride results in formation of complexes (II).
ChemInform Abstract: Au(I)‐Catalyzed and Iodine‐Mediated Cyclization of Enynylpyrazoles to Provide Pyrazolo[1,5‐a]pyridines.
Authors: Wu Hung‐Chou , Yang Chia‐Wen , Hwang Long‐Chih , Wu Ming‐Jung 
Published: February 2013

AbstractDerivatives (III) can be further converted by Suzuki‐Miyaura cross‐coupling reaction.
ChemInform Abstract: Unexpected Reactivity of Diaryl α‐Diketones with Thiazolium Carbenes: Discovery of a Novel Multicomponent Reaction for the Facile Synthesis of 1,4‐Thiazin‐3‐ones.
Authors: Bertolasi Valerio , Bortolini Olga , Donvito Adelaide , Fantin Giancarlo , Fogagnolo Marco , Giovannini Pier Paolo , Massi Alessandro , Pacifico Salvatore 
Published: February 2013

AbstractTwo methods with either elaborated temperature or microwave irradiation are also presented giving lower yields.
ChemInform Abstract: One‐Pot Synthesis of Benzo[1,4]thiazin‐3(4H)‐ones and a Theoretical Study of the S—N Type Smiles Rearrangement Mechanism.
Authors: Zhao Yongmei , Wu Yanmiao , Jia Jiong , Zhang Dongju , Ma Chen 
Published: February 2013

AbstractA new, simple, and environmentally friendly method to prepare biologically important benzothiazinones and related compounds is reported.
ChemInform Abstract: A New Synthetic Approach to Phenothiazine‐2‐amines.
Authors: Takacs Daniella , Egyed Orsolya , Drahos Laszlo , Riedl Zsuzsanna , Hajos Gyoergy 
Published: February 2013

AbstractA Buchwald—Hartwig protocol is presented for the introduction of amino and amide moieties into position‐2.
ChemInform Abstract: Regioselective Synthesis of New Bibracchial Lariat Ethers.
Authors: Ebrahimi Sattar , Mobinikhaldei Akbar , Foroughifar Naser 
Published: February 2013

AbstractUsing sodium hydride as the base, macrocycles (I) react with chloroacetic acid derivatives (II) to afford title ethers (III) as cis‐diastereomers.
ChemInform Abstract: Enantioselective Hydrogenation of β‐Ketophosphonates with Chiral Ru(II) Catalysts.
Authors: Tao Xiaoming , Li Wanfang , Ma Xin , Li Xiaoming , Fan Weizheng , Zhu Lvfeng , Xie Xiaomin , Zhang Zhaoguo 
Published: February 2013

AbstractThe chiral Ru complex (S)‐(RUC) efficiently promotes the asymmetric hydrogenation of β‐ketophosphonates yielding various optically active β‐hydroxyphosphonates of biological interest.
ChemInform Abstract: Efficient Synthesis of New Imidazo[1,2‐b][1,2]benzothiazine 4,4‐Dioxide Derivatives via Lateral Lithiation of N‐Mesitylenesulfonyl Hydantoins.
Authors: Kacem Yakdhane , Ben Hassine Bechir 
Published: February 2013

AbstractLithiation of hydantoins (IV) in the presence of TmsCl results in formation of racemic benzothiazine derivatives (V).