bluuebunny/crossref_metadata_2025_split huggingface dataset:
P-367 NMR-BASED METABOLOMICS: NOVEL APPLICATION IN EXPOSOMICS
Authors: Spagnoli Mariangela , Tranfo Giovanna , Giampaoli Ottavia , Sciubba Fabio , De Rosa Michele , Patriarca Adriano 
Published: July 2024

Abstract

Introduction
Metabolomics studies the end products of biological processes ocurring in living systems, based on the quantification of low molecular weight molecules in a specific biofluid to evaluate the changes in metabolism due to endogenous and/or exogenous stimuli. Nuclear magnetic resonance (NMR) has proven to be a very valuable analytical platform for its ability to quali-quantitatively characterize complex mixtures with minimal pretreatment and can be applied in the field of occupational medicine.

Methods
Urine samples of exposed workers and healthy non-exposed volunteers were collected from different biolmonitoring campaigns and analyzed by nuclear magnetic resonance (NMR) spectroscopy with mono and bidimensional experiments

Results
About 40 metabolites, including amino acids, organic acids, aromatic compounds and alcohols, were identified and quantified. It was also possible to identify and quantify both metabolites and dose biomarkers such as mandelic and phenilglyossilc acids in case of styrene exposure.

Discussion
By comparing the urinary metabolites of exposed and non-exposed it is possible to observe quantitative differences validated by univariate and multivariate statistical analysis. These differences may be attributable to metabolic alterations at a subclinical level and therefore provide indications on potential variations to be followed over time to predict the onset of occupational disease.

Conclusion
The application of NMR metabolomic approach in occupational medicine evidence a characteristic metabolic profile by identyfing early biomarkers of effect and their involvement in the metabolic pathway.
O-207 A MULTIDISCIPLINARY APPROACH TO MONITORING EMPLOYEES WITH NON-COMMUNICABLE DISEASES (NCDS) AT A ZAMBIAN MINE SITE - ENHANCING WORKER HEALTH AND WELL-BEING
Authors: Visage Christine , Miyanda Gloria 
Published: July 2024

Abstract

Introduction
Non-Communicable Diseases(NCDs) present a significant health challenge among the working population in Zambia, contributing to elevated morbidity and mortality. The COVID-19 pandemic brought to light the heightened vulnerability of employees with NCDs, prompting an intensified focus on proactive monitoring and effective management. Inadequately addressed NCDs extend to increased employee absenteeism, impacting individual well-being and workplace productivity.

Objective
This presentation illustrates the implementation of a multidisciplinary approach to identify and manage employees with NCDs, aiming to enhance control and reduce absenteeism. The team comprises of Occupational Health, Primary Health Care (including a dedicated NCD clinic with expedited patient care), First Aid Stations, Public Health, and Wellness Teams (Exercise Specialists, dedicated exercise groups, a Nutritionist, and Counselling Services.)

Methods and Results
This presentation provides insights into the roles of each member of the team, the challenges encountered during establishment, and highlights positive outcomes within the first year. Additionally, we analyse hospital and emergency room admissions data for clients with uncontrolled NCDs and absenteeism data from Occupational Health related to NCDs. We also discuss the positive impact of monthly NCD-stakeholder meetings in identifying high-risk cases and ensuring ongoing fitness for duty.

Discussion and Conclusion
Short-term results indicate reduced hospital admissions, and decreased absenteeism among previously identified cases. Positive feedback from clients underscores the effectiveness of this multidisciplinary approach to managing NCDs among mine site employees. Further research is needed to assess the long-term impact and sustainability. The approach holds promise not only for Zambia but also for similar contexts, wherein the intersection of health, work, and well-being is of paramount significance.
O-208 TRANSLATIONAL TRAINING IN OHS
Authors: Mittal Ashish 
Published: July 2024

Abstract

Introduction
Occupational health and safety in most of the small & medium enterprises end up as paper compliance of legal requirements. E.g. generic annual medical examination of workers is usually not based on the workplace hazard assessment and exposure to the respective workers. The idea behind the translational training is to improve the workers’ health, safety and wellbeing by enhancing transfer and adoption of science of OHS risks and outcomes in simplistic and sustainable participation of workers and organization.

Materials and Methods
A secondary literature review was combined with thirty shop floor training of workers, supervisors and managers in various small and medium enterprises.

Results
The hard to reach, resource crunched 63 million small and medium enterprises, employing more than 110 million workers across the country shy away from deploying OHS practices, thereby compromising health, safety and wellbeing of workers. The science of OHS is not understood by most of the stakeholders and perceived as a financial, logistic and behavioral burden to comply with.

Discussion and conclusion
With translational training, focusing on 5 why and 1 how, workers and other stakeholders understand and own their roles to recognize, reduce/ control the workplace risks, enhance their own physical, psychologic requires much research and data on appropriateness, adoption, practice and sustainability of such trainings.
O-209 ENHANCING OCCUPATIONAL HEALTH SERVICES THROUGH IN-HOUSE PHYSIOTHERAPY SERVICES: A CASE STUDY FROM A ZAMBIAN MINE SITE
Authors: Visage Christine 
Published: July 2024

Abstract

Background
Occupational Health Doctors in Zambia have long faced challenges related to limited rehabilitation resources, impacting employee well-being and return-to-work outcomes. This presentation explores the transformative impact of integrating in-house rehabilitative physiotherapy services into our Occupational Health team, as witnessed from the viewpoint of Occupational Health Doctors. Initially intended to address chronic lower back pain cases and enhance return-to-work outcomes for injury on duty cases, our in-house physiotherapist’s role evolved significantly during the COVID-19 pandemic when the emphasis shifted and he also assisted with respiratory and physical deconditioning rehabilitation.

Methods
Our team of Occupational Health Doctors collaborates closely with our Occupational Health Physiotherapy team, managing a diverse range of cases, including vertigo, cardio-respiratory issues, musculoskeletal disorders, and peripheral neuropathy. We provide insights into the methods employed, including Functional Capacity Evaluations, Pain Management Programs, Work Conditioning, and Work Hardening, as well as the pivotal role these services play in our practice.

Results
We present a compelling case study, demonstrating how our collaborative approach between Occupational Health Doctors and the Physiotherapy team has facilitated effective cardio-respiratory rehabilitation and the phased return-to-work plan for an employee with Tuberculous Pericarditis, Pleural effusion, gout, and hypertension. Our presentation sheds light on the outcomes observed by Occupational Health Doctors.

Discussion and Conclusion
The integration of in-house rehabilitative services has revolutionized our approach to assessing fitness-for-duty in Zambia. This collaborative model empowers employees on their journey to optimal well-being, and it holds particular promise for regions with limited rehabilitative resources, offering transformative changes in employee health.
P-374 EPIDEMIOLOGICAL STUDY OF NOISE-INDUCED HEARING DISORDERS AMONG MINING WORKERS IN GUINEA, 2018-2022
Authors: Tchicaya Aimé Francois 
Published: July 2024

Abstract

Introduction
The noisy nature of machines, tools, and work processes characterizes mining activities, creating an environment conducive to the development of hearing injuries.

Method
A cross-sectional descriptive study of hearing injuries among mine workers was conducted over a 3-month data collection period. We collected data through a questionnaire and processed using Epidata and Excel 16.

Results and discussion
The sample consisted of 345 employees out of 384, with a participation rate of 89.84%; 98.6% were male. The mean age was 45.94±8 years, ranging from 24 to 59 years, with heavy equipment operators accounting for 25.5% of the sample. Work hours exceeded 8 hours for 11.60% of employees. Sound intensity ranged from 69 dB (A) to 111 dB (A), with a 26 dB(A) gap beyond the standard at one station. The use of hearing protection was irregular among 86.10% of employees. The prevalence of hearing disorders was 75.10%, with deafness accounting for 30.70% of cases, including 2.31% severe and 6.67% moderate cases; 3.48% of hearing losses met recognition criteria, while we recognized none as occupational injuries.

Conclusion
Preventive measures are necessary to reduce the risk of occupational deafness. Keywords: Noise-exposure-hearing disorders-mining.
O-214 OCCUPATIONAL EXPOSURE TO HAZARDOUS CHEMICALS DURING PREGNANCY IN A PATHOLOGY LABORATORY CASE OF A PREGNANT TECHNICIAN EXPOSED TO TOLUENE
Authors: Norredine Doha , Wifaq Kamal , Tahri Loubna , Darid Fadwa , Jbara Meriem , El Kholti Abdeljalil 
Published: July 2024

Abstract

Introduction
The profession of pathology laboratory technician exposes various risks, notably chemical. Occupational exposure to hazardous chemicals during pregnancy can lead to foetotoxicity. The aim is to evaluate the work ability of a pregnant pathology laboratory technician.

Methods
To answer this request, an analysis of the state of health, a study of the workstation and exposure to hazardous chemicals and an evaluation of the physical load were carried out.

Results
A 37-year-old laboratory technician assigned to the anatomopathology laboratory’s sample reception room, treated for rheumatoid arthritis from 2020, 5 months pregnant and exposed to formaldehyde, ethanol, toluene and paraffin.

Discussion
According to the classification, labeling and packaging of substances and mixtures, toluene is classified as toxic for reproduction, Category 2, H361. Occupational exposure to toluene may lead to an increased incidence of spontaneous abortion, preterm birth, central nervous system anomalies and neural tube closure defects, cognitive and behavioral problems associated with developmental delays, including mental retardation, language impairment, and hyperactivity, hydranencephaly and other congenital malformations. These effects appear to depend upon the level of occupational exposure. Workstation modification was recommended with avoidance of exposure to foetotoxic substances.

Conclusion
Further evaluation of the potential toxicity of hazardous chemicals exposure is merited. Studies designed to clarify exposure effects, dose levels, and timing of exposure will be most valuable
O-224 DIFFICULTIES IN MAINTAINING EMPLOYMENT FOR WORKERS WITH BIPOLAR DISORDER: A STUDY ABOUT TEN CASES
Authors: Soltani Sara , El Kholti Rim , El Kholti Abdeljalil 
Published: July 2024

Abstract

Introduction
Bipolar disorder (BD) is a mental health condition that causes extreme mood swings. This disorder has been ranked as one of the 10 leading medical causes of disability. Difficulties in maintaining in employment are related to individual characteristics and/or work environment. The aim of this study is to assess the professional disintegration factors as well as keeping at work measures in people with BD.

Materials and methods
This is a descriptive cross-sectional survey concerning medical expertise of ten cases of workers with BD at Ibn Rochd University Hospital Center, during the period between April 2021 and August 2023.

Results
The population was presented by nine female and one male; six nurses, two residents and two administrators. The average age was 36 years (23-53), the average seniority was 13 years (1.5-29). Three patients had BD type II and three patients had comorbidities. Five patients were on long-term sick leave for psychotic characteristics, two patients benefited from an adaptation of the workstation and three patients had mutated to another structure.

Discussion
Professional functioning in patients with BD may concern by the type of bipolar spectrum, the existence of cognitive impairment, number/severity of symptoms, advanced age, level of education and comorbidity. Regularity of schedules, absence of night work and suited work were mentioned as having a positive impact on job retention.

Conclusion
Keeping people with BD at work is challenging. Management of these patients must address both clinical features and work environment to prevent unemployment.
O-227 WOLFF-PARKINSON-WHITE SYNDROME AND OCCUPATIONAL EXPOSURE TO ANAESTHETIC GASES: A CASE STUDY
Authors: Soltani Sara , El Kholti Rim , El Kholti Abdeljalil 
Published: July 2024

Abstract

Introduction
Wolff-Parkinson-White (WPW) syndrome is a ventricular pre-excitation due to congenital atrioventricular accessory conduction pathways. The risk of sudden death is around 0.3% per year in symptomatic patients and 0.1% per year in asymptomatic patients. Occupational exposures interfering with myocardial excitability call for extreme caution when deciding on fitness for work of these patients. The aim of this study is to discuss how occupational exposure to anaesthetic gases can increase the occurrence of tachyarrhythmia episodes in workers with WPW syndrome.

Materials and methods
Descriptive and analytic case study of a nurse assigned to the surgical emergency department of Ibn Rochd University Hospital, followed up for WPW syndrome, who complained of the occurrence of paroxysmal tachyarrhythmia after exposure to anesthetic gases in the workplace.

Results
The case involves a 39-year-old nurse, working in the operating room for 20 years. The average heart rate during the work cycle (2h 13) was 116 bpm (maximum of 138 bpm). The anaesthetic gas used was Sevoflurane, the other commonly used gases being Halothane and Isoflurane.

Discussion
The effects of occupational exposure to anaesthetic gases on the incidence of tachyarrhythmias in workers with WPW syndrome are unknown. The suitability of Sevoflurane as an anaesthetic agent for patients with WPW undergoing ablative procedures has been approved. However, several halogenated anaesthetics have been described as peripheral vasodilators or as having a myocardial depressant effect on patients.

Conclusion
The risk of sudden death in workers with WPW requires professional reclassification as a precautionary measure, considering occupational exposure conditions.
O-233 COVID-19 PANDEMIC, OCCUPATIONAL SAFETY AND HEALTH (OSH) AND IMPACT ON BUSINESS SUSTAINABILITY IN ACCOUNTING AND CONSULTING FIRM
Authors: Benbrahim Anissa , Mekouar Faiçal , Bennouna Ali , El Kholti Rim , El Kholti Abdeljalil 
Published: July 2024

Abstract

Introduction
The COVID-19 pandemic has had an unprecedented impact on global workplaces, reshaping how businesses operate and highlighting the critical importance of OHS for the sustainability of businesses. What’s happened in Fidaroc Grant Thornton (FGT)?

Methods
Assessing the impact of the COVID-19 pandemic on workplaces requires a systematic approach and the use of various materials and methods like Data Collection Forms, Questionnaires and Surveys, Data Analysis, Benchmarking, Workplace Policies and Guidelines.

Results
The action plan contained: Health and Safety Measures: Enhanced sanitation measures, mandatory mask-wearing, temperature checks, and social distancing became the new norms in workplaces. Remote Work and Flexibility to maintain business continuity by relevant planning. Mental health became a central concern in OHS. Travel restrictions led to a surge in virtual meetings. Redefining Workspaces. Employee Training and Education. Assessment and Risk Management. Campaign vaccine. New OHS regulations and guidelines specific to COVID-19.

Discussion
COVID-19 pandemic has brought OSH to the forefront of business concerns. Implementing effective OHS measures has become not only a legal and ethical obligation but also a key factor in ensuring the sustainability and resilience of businesses in the face of unexpected challenges. Businesses that prioritize the health and safety of their employees are better positioned to adapt, recover, and thrive in the post-pandemic world.

Conclusion
While the COVID-19 pandemic brought challenges, it also provided opportunities for businesses to reassess their practices. The integration of OHS and sustainability considerations by FGT has enabled its activity to be more resilient and better prepared for future challenges.
O-234 OCCUPATIONAL SAFETY AND HEALTH (OSH) TO ACCOUNTING AND AUDITOR’S PROFESSION (AAP) AND ITS IMPACT ON ENVIRONMENTAL, SOCIAL, GOVERNANCE (ESG) CRITERIA
Authors: Mekouar Faiçal , Agoumi Fadel , El Kholti Rim , El Kholti Abdeljalil 
Published: July 2024

Abstract

Introduction
OEC Morocco wants to offer a robust organization of OSH to its members in the aim to bring several benefits to AAP, while also positively impacting ESG considerations.

Materials and Methods
Action plan is tailored to create a safer and healthier work environment to ensure compliance with Moroccan’s OSH regulations and international labor standards.

Results
Here’s how OSH and ESG aspects can be interconnected: employee well-being, talent attraction and retention, positive reputation, governance and ethics, social responsibility, long-term sustainability. By prioritizing OSH, businesses improve employee health and well-being, productivity, and overall organizational efficiency. It’s also contributing positively to an organization’s ESG profile and sustainable business practices.

Discussion
Incorporating OSH actions in AAP not only improves workplace conditions but also aligns with ESG considerations. Robust OSH practices are indicative of strong governance, creating a more sustainable and responsible business environment, demonstrating a commitment to a key social consideration, demonstrating transparent reporting on OSH performance metrics can enhance accountability and credibility of AAP both for its employees and for its customers, which are important elements of the ESG framework.

Conclusion
A well-organized approach to OSH within AAP can lead to enhanced employee well-being, positive ESG outcomes, and a reputation for ethical and responsible practices. By integrating health, safety, and ESG considerations, AAP can create a safe and health workplace and a sustainable and ethical business environment.
O-238 PERSONALITY TRAITS AND WORKPLACE WELL-BEING AMONG SPECIALIST DOCTORS: A STUDY OF 88 CASES
Authors: Youabd Saadia , Wifaq Kamal , Tahri Loubna , Omali Asmaa , El Kholti Abdeljalil 
Published: July 2024

Abstract

Introduction
The five major personality traits are crucial in how individuals approach their work, especially in the medical sector. This study examines how these traits influence workplace well-being indicators, including work capacity, psychological distress, sleep problems, and suicidal thoughts.

Materials and Methods
Survey conducted through an online self-questionnaire using “Google Forms,” based on validated psychological tests. The target population consisted of resident doctors and recently graduated specialists affiliated with Ibn Rochd University Hospital in Casablanca.

Results
88 doctors participated (15%). The most predominant personality trait was agreeableness (42.04%), followed by conscientiousness (31.81%), neuroticism (17.04%), openness (9.09%), and no extraversion trait. Doctors specializing in psychiatry-child psychiatry, occupational medicine, and oncology-radiation therapy, who exhibited an agreeable personality trait, seemed to experience better workplace well-being, with satisfactory work capacity (40.54%), absence of psychological distress (62.16%), few or no sleep problems (54.05%), and no suicidal thoughts (83.78%). Conversely, doctors primarily specializing in cardiology and radiology, displaying a neuroticism personality trait, appeared to have lower workplace well-being, with slightly to significantly reduced work capacity (60%), frequent psychological distress (93.33%), moderate sleep problems (46.67%), and the presence of suicidal thoughts (53.33%).

Discussion
Limited research results suggest that doctors with a high level of neuroticism and low conscientiousness tend to have lower professional well-being. Conversely, high extraversion and agreeableness are often associated with better well-being.

Conclusion
The study underscores the importance of considering doctors’ personality traits to improve their working conditions. It sheds light on an essential aspect of physicians’ occupational health and paves the way for future research and interventions.
O-239 VALUE OF SPIROMETRY IN THE DIAGNOSIS OF OCCUPATIONAL ASTHMA: A CASE STUDY OF A PHARMACY ASSISTANT
Authors: Jbara Meriem , Wifaq Kamal , Tahri Loubna , Darid Fadwa , El Kholti Abdeljalil 
Published: July 2024

Abstract

Introduction
The preparation of cytotoxic drugs leads to the risk of chemical contamination of the operator through contact or inhalation. The aim of this study was to assess the impact of cytotoxic exposure on the lung function of a pharmacy assistant.

Materials and methods
In response to the request of a medical expertise established at the Occupational Health Department of Ibn Rochd University Hospital in Casablanca, a real-time workstation study was carried out where three spirometry tests were done: during exposure, after one and two weeks from exposure.Also, a bibliographical study of the toxicity of the cytotoxic drugs was handled.

Results
The pharmacy assistant was treated for allergic rhinitis and severe anosmia since 2019, complicated by shortness of breath. The preparation room is equipped with two cytotoxic safety workstations and an isolator, which are functional with appropriate ventilation. Spirometry tests perfomed haven’t revealed any abnormalities, apart from a restrictive disorder.

Discussion
No link was established between exposure to cytotoxics and the assistant’s condition, therefore, we recommended no arrangements but regular monitoring of her state of health and compliance with safe handling rules. Spirometry is a valid test to confirm work exposures’ impact on lung function: In symptomatic workers exposed to the suspected causative agent, a negative result almost rules out the diagnosis of work-related asthma.

Conclusion
Health risks associated with the handling manipulation of cytotoxic drugs are a major occupational health concern. All personnel must be trained and qualified in the safe, aseptic handling of these products.