bluuebunny/crossref_metadata_2025_split huggingface dataset:
Geodäsie im Investitionsbauprozess auf den Bahngebieten in Polen
Authors: Kampczyk Arkadiusz 
Published: June 2014

AbstractDer Artikel bezieht sich auf die gegenwärtigen Organisationsstrukturen der Geodäsie und die sie begleitenden organisatorischen Einheiten mit Investitionscharakter auf den Bahngebieten in Polen, die im Investitionsbauprozess von erheblicher Bedeutung sind. Der vorliegende Beitrag erläutert den geltenden Fachwortschatz und die Funktion der Organisationsstrukturen. Es wird dabei hervorgehoben, dass die polnischen Bahngebiete zu den sog. geschlossenen Gebieten gehören. Die Thematik spielt eine wesentliche Rolle im Investitionsprozess für den Bahnverkehr und die Bahninfrastruktur. In den letzten Jahren kamen im Bereich des Bauinvestitionsprozesses für den Bahnverkehr und die Bahninfrastruktur sowie der Funktion der Organisationsstrukturen der Geodäsie, die mit der Gründung der neuen organisatorischen Einheit mit dem Investitionscharakter verbunden war, gravierende Veränderungen zustande. In der vorliegenden Arbeit werden die von dem Autor zusammengestellten Erkenntnisse, Fazits und Anmerkungen zu diesem Aspekt vorgestellt. Der Beitrag entstand im Rahmen der Satzungsuntersuchungen Nr. AGH 11.11.150.005.Surveying in construction investment process in the areas of railway in PolandThis article applies to current organizational structures of geodesy and its associated units of investment on railway premises in Poland, which play a vital role in building the investment process. Zooms in legal terms and their organizational structures. Attention is drawn to the fact that the railway areas in Poland belong to the so‐called closed areas. This subject plays an important role in the investment process, communication and infrastructure construction. In recent years, Poland experienced a big change in the investment process and transport construction of railway infrastructure and the functioning of the organizational structures of surveying with the appointment of a new organizational unit of investment. The paper presents the author remarks, conclusions and comments. This work was done within the framework of statutory research AGH No. 11.11.150.005.
Herausforderung Sri Lanka
Authors: Nagel Sven , Müller Anthea , Walter David , Hildenbrand Geza , Haas Fabian 
Published: June 2014

AbstractStudenten aus Karlsruhe initiieren, planen und verwirklichen eigenverantwortlich ingenieurstechnische Entwicklungsprojekte weltweit. In diesem Bericht werden die Herausforderungen eines solchen Projektes am Beispiel der im Sommer 2013 fertiggestellten Hängebrücke im Süden Sri Lankas dargestellt. Neben der Suche nach einem passenden Projekt stellen die Finanzierung sowie die Vorbereitung des Teams auf kulturelle Eigenheiten fundamentale Aufgaben dar. Bei der Planung muss eine Konstruktion entwickelt werden, die den besonderen Beanspruchungen durch den srilankischen Dschungel dauerhaft trotzt und in einer einfachen Bauweise ohne schwere Baumaschinen und ausgebildete Fachkräfte gebaut werden kann. Um dies zu erreichen ist es erforderlich, sich in mancher Hinsicht von den im Studium gelernten Standards und Techniken zu lösen und eigene Konzepte zu entwerfen. In der knapp viermonatigen Bauphase sorgen Kommunikationsprobleme, Schwierigkeiten bei der Terminplanung und Materialbeschaffung sowie Tropenstürme für einen abwechslungsreichen Alltag auf der Baustelle. Nach dem Abschluss des Projektes zeigt sich, dass vor allem ein verlässliches Team, Durchhaltevermögen und die enge Zusammenarbeit mit den Menschen vor Ort für die erfolgreiche Umsetzung unabdingbar sind.Challenge Sri Lanka – prospective engineers build suspension bridge in the jungleStudents from Karlsruhe University initiate, plan and develop engineering projects worldwide with sole responsibility. In summer 2013 they built a suspension bridge in a small village in the Sri Lankan jungle. This report is going to show and emphasize the challenges which come along with conducting such a project. Next to the project itself the funding needs to be discussed clearly as well as the fact that the whole team needs to be confronted with possible cultural differences and characteristics. Considering the construction of the suspension bridge it needs to be kept in mind that the material needs to be extremely solid due to the Sri Lankan humid climate. The construction of the bridge is supposed to be planned as simple as possible. University students and villagers who are not familiar with working on a construction site are going to build the bridge. In addition for logistical reasons it is not possible to bring and move big construction machines into the Sri Lankan jungle. Therefore it is necessary to throw acquired knowledge overboard and to come up with own creative concepts and ideas. The suspension bridge had been built and finished within four months. Because of communication problems, tropical storms as well as difficulties in accurate project planning and purchasing no day on the construction site was like the other. Looking back a reliable team, staying power and a close cooperation with the villagers is indispensable for completing such a tremendous project successfully.
Spannbetonbau in der DDR
Authors: Bolle Guido , Schacht Gregor , Marx Steffen 
Published: June 2014

AbstractDer Beitrag gibt einen Überblick über die in der ehemaligen DDR eingesetzten Spannverfahren und stellt eines davon, das Verfahren ITB, ausführlich vor. Beim Abbruch der Brücke des 10. Jahrestages in Neubrandenburg, bei deren Errichtung dieses Spannverfahren erstmals zum Einsatz kam, wurden Material‐ und Bauteilproben entnommen und diese experimentell untersucht. Mit dem Ziel, das Schubversagen eines Spannbetonbauteils ohne schlaffe Betonstahlbewehrung zu untersuchen, wurde ein aus der Brücke herausgetrennter Träger einem Bruchversuch unterzogen, wobei verschiedene Messverfahren, wie die Photogrammetrie, die Schallemissionsanalyse und die bereichsweise Krümmungsmessung zum Einsatz kamen. Die Ergebnisse dieser experimentellen Untersuchungen werden ausführlich vorgestellt und das Tragverhalten hinsichtlich einer Versagensvorankündigung bewertet.Investigations on a pre‐stressed concrete bridge beam without pre‐tensioned reinforcementThe paper gives an overview of the pre‐stressing systems used in the former GDR and describes one system, called ITB, in detail. During the demolition of the bridge “10. Jahrestag” in Neubrandenburg, at which this pre‐stressing system was first used, material samples and a specimen were taken and experimentally investigated. For the objective of the investigation of a pre‐stressed concrete element without non‐pre‐stressed reinforcement, a cut out beam of a bridge was loaded until failure and different measuring technologies, like the photogrammetry, the acoustic emission analyses and the sectionwise curvature‐measurement were used. The results of this experimental investigation are discussed in detail and the bearing behavior according to an unannounced failure is evaluated.
Fluorescent studies on the interaction of DNA and ternary lanthanide complexes with cinnamic acid‐phenanthroline and antibacterial activities testing
Authors: Sun Hui‐Juan , Wang Ai‐Ling , Chu Hai‐Bin , Zhao Yong‐Liang 
Published: June 2014

ABSTRACTTwelve lanthanide complexes with cinnamate (cin–) and 1,10‐phenanthroline (phen) were synthesized and characterized. Their compositions were assumed to be RE(cin)3phen (RE3+ = La3+, Pr3+, Nd3+, Sm3+, Eu3+, Gd3+, Tb3+, Dy3+, Ho3+, Tm3+, Yb3+, Lu3+). The interaction mode between the complexes and DNA was investigated by fluorescence quenching experiment. The results indicated the complexes could bind to DNA and the main binding mode is intercalative binding. The fluorescence quenching constants of the complexes increased from La(cin)3phen to Lu(cin)3phen. Additionally, the antibacterial activity testing showed that the complexes exhibited excellent antibacterial ability againstEscherichia coli, and the changes of antibacterial ability are in agreement with that of the fluorescence quenching constants. Copyright © 2014 John Wiley & Sons, Ltd.
Fractional factorial design to investigate stromal cell regulation of macrophage plasticity
Authors: Barminko Jeffrey A. , Nativ Nir I. , Schloss Rene , Yarmush Martin L. 
Published: June 2014

ABSTRACTUnderstanding the regulatory networks which control specific macrophage phenotypes is essential in identifying novel targets to correct macrophage mediated clinical disorders, often accompanied by inflammatory events. Since mesenchymal stromal cells (MSCs) have been shown to play key roles in regulating immune functions predominantly via a large number of secreted products, we used a fractional factorial approach to streamline experimental evaluation of MSC mediated inflammatory macrophage regulation. Our macrophage reprogramming metrics, human bone marrow MSC attenuation of macrophage pro‐inflammatory M1 TNFα secretion and simultaneous enhanced expression of the M2 macrophage marker, CD206, were used as analysis endpoints. Objective evaluation of a panel of MSC secreted mediators indicated that PGE2 alone was sufficient in facilitating macrophage reprogramming, while IL4 only provided partial reprogramming. Inhibiting stromal cell PGE2 secretion with Indomethacin, reversed the macrophage reprogramming effect. PGE2 reprogramming was mediated through the EP4 receptor and indirectly through the CREB signaling pathway as GSK3 specific inhibitors induced M1 macrophages to express CD206. This reprogramming pathway functioned independently from the M1 suppression pathway, as neither CREB nor GSK3 inhibition reversed PGE2 TNF‐α secretion attenuation. In conclusion, fractional factorial experimental design identified stromal derived PGE2 as the factor most important in facilitating macrophage reprogramming, albeit via two unique pathways. Biotechnol. Bioeng. 2014;111: 2239–2251. © 2014 Wiley Periodicals, Inc.
The continuum heterogeneous biofilm model with multiple limiting substrate Monod kinetics
Authors: Gonzo Elio Emilio , Wuertz Stefan , Rajal Veronica B. 
Published: June 2014

ABSTRACTWe describe a novel procedure to estimate the net growth rate of biofilms on multiple substrates. The approach is based on diffusion‐reaction mass balances for chemical species in a continuum biofilm model with reaction kinetics corresponding to a Double‐Monod expression. This analytical model considers a heterogeneous biofilm with variable distributions of biofilm density, activity, and effective diffusivity as a function of depth. We present the procedure to estimate the effectiveness factor analytically and compare the outcome with values obtained by the application of a rigorous numerical computational method using several theoretical examples and a test case. A comparison of the profiles of the effectiveness factor as a function of the Thiele modulus, φ, revealed that the activity of a homogeneous biofilm could be as much as 42% higher than that of a heterogeneous biofilm, under the given conditions. The maximum relative error between numerical and estimated effectiveness factor was 2.03% at φ near 0.7 (corresponding to a normalized Thiele modulus φ* = 1). For φ < 0.3 or φ > 1.4, the relative error was less than 0.5%. A biofilm containing aerobic ammonium oxidizers was chosen as a test case to illustrate the model's capability. We assumed a continuum heterogeneous biofilm model where the effective diffusivities of oxygen and ammonium change with biofilm position. Calculations were performed for two scenarios; Case I had low dissolved oxygen (DO) concentrations and Case II had high DO concentrations, with a concentration at the biofilm–fluid interface of 10 g O2/m3. For Case II, ammonium was the limiting substrate for a biofilm surface concentration, CNs, ≤13.84 g of N/m3. At these concentrations ammonium was limiting inside the biofilm, and oxygen was fully penetrating. Conversely, for CNs > 13.84 g of N/m3, oxygen became the limiting substrate inside the biofilm and ammonium was fully penetrating. Finally, a generalized procedure to estimate the effectiveness factor for a system with multiple (n > 2) limiting substrates is given. Biotechnol. Bioeng. 2014;111: 2252–2264. © 2014 Wiley Periodicals, Inc.
The use of high pressure CO2‐facilitated pH swings to enhance in situ product recovery of butyric acid in a two‐phase partitioning bioreactor
Authors: Peterson Eric C. , Daugulis Andrew J. 
Published: June 2014

ABSTRACTThrough the use of high partial pressures of CO2 (pCO2) to facilitate temporary pH reductions in two‐phase partitioning bioreactors (TPPBs), improved pH dependent partitioning of butyric acid was observed which achieved in situ product recovery (ISPR), alleviating end‐product inhibition (EPI) during the production of butyric acid by Clostridium tyrobutyricum (ATCC 25755). Through high pressure pCO2 studies, media buffering effects were shown to be substantially overcome at 60 bar pCO2, resulting in effective extraction of the organic acid by the absorptive polymer Pebax® 2533, yielding a distribution coefficient (D) of 2.4 ± 0.1 after 1 h of contact at this pressure. Importantly, it was also found that C. tyrobutyricum cultures were able to withstand 60 bar pCO2 for 1 h with no decrease in growth ability when returned to atmospheric pressure in batch reactors after several extraction cycles. A fed‐batch reactor with cyclic high pCO2 polymer extraction recovered 92 g of butyric acid to produce a total of 213 g compared to 121 g generated in a control reactor. This recovery reduced EPI in the TPPB, resulting in both higher productivity (0.65 vs. 0.33 g L−1 h−1) and yield (0.54 vs. 0.40). Fortuitously, it was also found that repeated high pCO2‐facilitated polymer extractions of butyric acid during batch growth of C. tyrobutyricum lessened the need for pH control, and reduced base requirements by approximately 50%. Thus, high pCO2‐mediated absorptive polymer extraction presents a novel method for improving process performance in butyric acid fermentation, and this technique could be applied to the bioproduction of other organic acids as well. Biotechnol. Bioeng. 2014;111: 2183–2191. © 2014 Wiley Periodicals, Inc.
Preparative crystallization of a single chain antibody using an aqueous two‐phase system
Authors: Huettmann Hauke , Berkemeyer Matthias , Buchinger Wolfgang , Jungbauer Alois 
Published: June 2014

ABSTRACTA simultaneous crystallization and aqueous two‐phase extraction of a single chain antibody was developed, demonstrating process integration. The process conditions were designed to form an aqueous two‐phase system, and to favor crystallization, using sodium sulfate and PEG‐2000. At sufficiently high concentrations of PEG, a second phase was generated in which the protein crystallization occurred simultaneously. The single chain antibody crystals were partitioned to the top, polyethylene glycol‐rich phase. The crystal nucleation took place in the sodium sulfate‐rich phase and at the phase boundary, whereas crystal growth was progressing mainly in the polyethylene glycol‐rich phase. The crystals in the polyethylene glycol‐rich phase grew to a size of >50 µm. Additionally, polyethylene glycol acted as an anti‐solvent, thus, it influenced the crystallization yield. A phase diagram with an undersaturation zone, crystallization area, and amorphous precipitation zone was established. Only small differences in polyethylene glycol concentration caused significant shifts of the crystallization yield. An increase of the polyethylene glycol content from 2% (w/v) to 4% (w/v) increased the yield from approximately 63–87%, respectively. Our results show that crystallization in aqueous two‐phase systems is an opportunity to foster process integration. Biotechnol. Bioeng. 2014;111: 2192–2199. © 2014 Wiley Periodicals, Inc.
A microgroove patterned multiwell cell culture plate for high‐throughput studies of cell alignment
Authors: Lücker Petra B. , Javaherian Sahar , Soleas John P. , Halverson Duncan , Zandstra Peter W. , McGuigan Alison P. 
Published: June 2014

ABSTRACTGrooved substrates are commonly used to guide cell alignment and produce in vitro tissues that mimic certain aspects of in vivo cellular organization. These more sophisticated tissues provide valuable in vitro models for testing drugs and for dissecting out molecular mechanisms that direct tissue organization. To increase the accessibility of these tissue models we describe a simple and yet reproducible strategy to produce 1 µm‐spaced grooved well plates suitable for conducting automated analysis of cellular responses. We characterize the alignment of four human cell types: retinal epithelial cells, umbilical vein endothelial cells, foreskin fibroblasts, and human pluripotent stem‐cell‐derived cardiac cells on grooves. We find all cells align along the grooves to differing extents at both sparse and confluent densities. To increase the sophistication of in vitro tissue organization possible, we also created hybrid substrates with controlled patterns of microgrooved and flat regions that can be identified in real‐time using optical microscopy. Using our hybrid patterned surfaces we explore: (i) the ability of neighboring cells to provide a template to organize surrounding cells that are not directly exposed to grooved topographic cues, and (ii) the distance over which this template effect can operate in confluent cell sheets. We find that in fibroblast sheets, but not epithelial sheets, cells aligned on grooves can direct alignment of neighboring cells in flat regions over a limited distance of approximately 200 μm. Our hybrid surface plate provides a novel tool for studying the collective response of groups of cells exposed to differential topographical cues. Biotechnol. Bioeng. 2014;111: 2537–2548. © 2014 Wiley Periodicals, Inc.
Study on the pharmacokinetics and metabolism of costunolide and dehydrocostus lactone in rats by HPLC‐UV and UPLC‐Q‐TOF/MS
Authors: Peng Zhangxiao , Wang Yan , Gu Xue , Guo Xiaojie , Yan Chao 
Published: June 2014

ABSTRACTA method based on high‐performance liquid chromatography coupled with ultraviolet detection was developed for studying the pharmacokinetics of costunolide (Cos) and dehydrocostus lactone (Dehy) in rats after intravenous (i.v.) administration. Following i.v. administration, the maximum plasma concentrations of Cos and Dehy were observed to be 12.29 ± 1.47 and 5.79 ± 0.13 µg/mL, respectively. The bioavailability of Cos was larger than that of Dehy; however, the clearance and the volume of distribution of Dehy were much larger than those of Cos. An ultraperformance liquid chromatography/quadrupole time‐of‐flight mass spectrometry system with automated MSE (E represents collision energy) data analysis software (MetaboLynxTM) was used to analyze and identify the metabolites of Cos and Dehy in vivo. Four metabolites of Cos and six metabolites of Dehy were discovered from the plasma, urine and feces of rats. The main metabolic pathway of Cos was phase II biotransformation, but the main metabolic pathways of Dehy was phase І biotransformation. Two sequential desaturations and N‐acetylcysteine conjugation were the common metabolic pathways of Cos and Dehy in rats. This information may be useful for the further development of the two drug candidates. Copyright © 2014 John Wiley & Sons, Ltd.
Confinement of CuII–Phthalocyanine in a Bioinspired Hybrid Nanoparticle‐Assembled Structure Yields Selective and Stable Epoxidation Catalysts
Authors: Manna Joydeb , Amali Arlin Jose , Rana Rohit Kumar 
Published: June 2014

AbstractHerein, we demonstrate that a bioinspired assembly of silica nanoparticles with polyamines as structure‐directing agents similar to that known for the biosilicification of diatoms can pave the way for the efficient encapsulation of sulfonated copper–phthalocyanine in a hybrid microcapsule structure, in which the organic component provides a capable environment for its catalytic activity in epoxidation reactions and the nanoassembled structure imparts stability.
ChemInform Abstract: Structural Distortion and Band Gap Opening of Hard MnB4 in Comparison with CrB4 and FeB4.
Authors: Yang Meng , Wang Yachun , Yao Jinlei , Li Zhiping , Zhang Jian , Wu Lailei , Li Hui , Zhang Jingwu , Gou Huiyang 
Published: June 2014

AbstractFirst‐principles calculations are presented for monoclinic MnB4 as well as orthorhombic CrB4 and FeB4.
ChemInform Abstract: Single Crystal X‐Ray Structure of Cu3TaSe4 and a Comparative Study of Cu3MX4 (M: V, Nb, Ta; X: S, Se, Te).
Authors: Ali Sk Imran , van Smaalen Sander 
Published: June 2014

AbstractSingle crystals of Cu3TaSe4 are obtained from a precursor that is produced by chemical vapor reaction of Cu, Ta, and Se in a molar ratio of 0.21:1.15:2 (quartz ampoule in two‐zone furnace, 1.
ChemInform Abstract: Pressure‐Induced Intersite Bi—M (M: Ru, Ir) Valence Transitions in Hexagonal Perovskites.
Authors: Ling Chris D. , et al. et al. 
Published: June 2014

AbstractPressure‐induced charge transfer from Bi to Ir/Ru in Ba3BiIr2O9, Ba3BiRu2O9, and Ba4BiIr3O12 is investigated by high‐pressure single crystal XRD, high‐pressure neutron powder diffraction, and DFT calculations.
ChemInform Abstract: Synthesis and Optical Properties of Li3Ba2La3 (MoO4)8:Sm3+ Powders for pcLEDs.
Authors: Baur Florian , Katelnikovas Arturas , Sakirzanovas Simas , Petry Ralf , Juestel Thomas 
Published: June 2014

AbstractThe series of Li3Ba2(La1‐xSmx)3 (MoO4)8 (0 ≤ x ≤ 1) compounds for phosphor‐converted LEDs is prepared by solid state reaction of stoichiometric amounts of Li2CO3, BaCO3, La2O3, MoO3, and Sm2O3 (porcelaine crucibles, air, 800 °C, 10 h).
ChemInform Abstract: Three Series of Quaternary Rare‐Earth Transition‐Metal Pnictides with CaAl2Si2‐Type Structures: RECuZnAs2, REAgZnP2, and REAgZnAs2.
Authors: Stoyko Stanislav S. , Ramachandran Krishna K. , Blanchard Peter E. R. , Rosmus Kimberly A. , Aitken Jennifer A. , Mar Arthur 
Published: June 2014

AbstractThree series of quaternary pnictides, LnCuZnAs2 (Ln: Y, La—Nd, Sm, Gd—Lu), LnAgZnP2 (Ln: La—Nd, Sm, Gd—Dy), and LnAgZnAs2 (Ln: La—Nd, Sm, Gd—Dy) are prepared by solid reaction of the elements (evacuated silica tubes, 1.
ChemInform Abstract: Synthesis and Structural Characterization of Yttrium Polyphosphates AY(PO3)4 (A: Rb, Tl, Cs) and Site‐Selective Spectroscopy of Eu3+ Doped Samples.
Authors: Oudahmane Abdelghani , Barros Anthony , Avignant Daniel , Zambon Daniel 
Published: June 2014

AbstractThe new long‐chain polyphosphates MY(PO3)4 (M: Rb, Tl, Cs) are prepared by solid state reaction of stoichiometric mixtures of M2CO3, Y2O3, and NH4H2PO4 (Pt crucible, 400—450 °C, 36 h).
ChemInform Abstract: Heterogeneous versus Homogeneous Copper(II) Catalysis in Enantioselective Conjugate‐Addition Reactions of Boron in Water.
Authors: Kitanosono Taku , Xu Pengyu , Kobayashi Shu 
Published: June 2014

AbstractThe authors compare one heterogeneous and two homogeneous copper catalyst systems for the hydroboration of unsaturated ketones followed by oxidative deboration.
ChemInform Abstract: Iron(III)triflate as a Highly Efficient, Recyclable and Green Catalyst for the N‐Boc Protection of Amines.
Authors: Feng Chengliang , Chu Ningning , Zhang Shuguang , Cai Jin , Chen Junqing , Hu Huayou , Ji Min 
Published: June 2014

AbstractVarious aliphatic, aromatic, and heterocyclic amines as well as aminols are selectively protected as monocarbamates in excellent yields and short reaction times.
ChemInform Abstract: An Efficient Catalyst for Ring Opening of Epoxides with Phenol and Thiophenol under Solvent‐Free Conditions.
Authors: Lu Hong‐fei , Zhou Jun‐tao , Cheng He‐long , Sun Lei‐lei , Yang Fei‐fei , Wu Run‐ze , Gao Yu‐hua , Luo Zhi‐bin 
Published: June 2014

AbstractNotable advantages of the title process are solvent‐free conditions, short reaction times, simple operation, high yields, and reusability of the catalyst.
ChemInform Abstract: Synthesis of Novel Chiral Bidentate Hydroxyalkyl‐N‐heterocyclic Carbene Ligands and Their Application in Palladium‐Catalyzed Mizoroki—Heck Couplings and Asymmetric Addition of Diethylzinc to Benzaldehyde.
Authors: Faraji Laleh , Jadidi Khosrow , Notash Behrouz 
Published: June 2014

AbstractThe chiral hydroxyalkyl‐NHC ligand is prepared from leucine on a multi‐gram scale.