bluuebunny/crossref_metadata_2025_split huggingface dataset:
PSIKOEDUKASI DAN FGD DALAM MEMBANGUN KOLABORASI ORANG TUA DAN GURU DI SDIT DARUL IHSAN PONTIANAK
Authors: Baroroh Ema Zati , Amalia Putri Rizka , Amalia Andria Putri  
Published: August 2024

Kegiatan pengabdian ini bertujuan untuk meningkatkan pemahaman orang tua dan guru terkait kolaborasi dan membantu keduanya untuk mencapai kesepakatan dalam kolaborasi. Lokasi pengabdian dilaksanakan di SDIT Darul Ihsan. Peserta pengabdian berjumlah 22 orang yang terdiri dari orang tua dan guru. Kegiatan pengabdian ini memiliki 2 tahap yaitu Psikoedukasi dan FGD. Psikoedukasi bertujuan untuk menambah pengetahuan peserta terkait kolaborasi. FGD bertujuan untuk menghasilkan kesepakatan kolaborasi antara orang tua dan guru. Pengabdian ini dilaksanakan pada Sabtu, 04 November 2023. Kuisioner yang terdiri dari 20 soal terkait kolaborasi orang tua dan guru digunakan sebagai instrumen untuk mengukur tingkat pemahaman peserta. Hasil kegiatan yang telah dilaksanakan menunjukkan bahwa ada perubahan tingkat pengetahuan peserta terkait kolaborasi orang tua dan guru. Selain itu pada kegiatan ini terciptanya 5 butir bentuk kolaborasi yang telah disepakati orang tua dan guru. Dengan adanya kegiatan ini, kolaborasi antara orang tua dan guru menjadi lebih optimal dengan kesepakatan yang telah tercapai.
PENGARUH KEKUATAN OTOT TUNGKAI, KEKUATAN OTOT LENGAN DAN KOORDINASI MATA TANGAN TERHADAP KETEPATAN SMASH BOLA VOLI
Authors: Iksal Muh. , Kahar Irsan , Nur Suaib , Ahmad Ahmad , Hidayat Rachmat 
Published: August 2024

Penelitian ini bertujuan untuk mengetahui pengaruh kekuatan otot tungkai, kekuatan otot lengan dan koordinasi mata tangan terhadap ketepatan smash bola voli. Teknik analisis data yang digunakan adalah analisis deskriptif, uji asumsi klasik dan analisis jalur taraf signifikan Î± 0,05. Hasil penelitian menunjukkan bahwa; (1) ada pengaruh langsung kekuatan otot tungkai terhadap koordinasi mata tangan pada ekstrakurikuler bola voli dengan nilai beta 0,452 dengan signifikan 0,009< Î± 0,05; (2) ada pengaruh langsung kekuatan ototÂ lengan terhadap koordinasi mata tangan pada ekstrakurikuler bola voli dengan nilai beta 0,557 dengan signifikan 0,002< Î± 0,05; (3) ada pengaruh langsung kekuatan otot tungkai terhadap ketepatan smash pada ekstrakurikuler bola voli dengan nilai beta 0,627 dengan signifikan 0,001< Î± 0,05; (4) ada pengaruh langsung kekuatan otot lengan terhadap ketepatan smash pada ekstrakurikuler bola voli dengan nilai beta -0,377 dengan signifikan 0,043< Î± 0,05; (5) adaÂ pengaruh langsung koordinasi mata tangan terhadap ketepatan smash pada ekstrakurikuler bola voli dengan nilai beta 0,681 dengan signifikan 0,010< Î± 0,05; (6) ada pengaruh kekuatan otot tungkai terhadap ketepatan smash melalui koordinasi mata tangan pada ekstrakurikuler bola voli dengan nilai beta 0,307 dengan signifikan 0,000< Î± 0,05; (7) ada pengaruh kekuatan otot lengan terhadap ketepatan smash melalui koordinasi mata tangan pada ektrakurikuler bola voli dengan nlai beta 0,379 dengan signifikan 0,000< Î± 0,05.
Optimasi Quercetin Kombinasi Avobenzone dalam Sediaan Spray Lotion Tabir Surya
Authors: Wisudyaningsih Budipratiwi , Rimadani Elok , Ameliana Lidya , Sari Lusia Oktora Ruma Kumala , Wicaksono Yudi , Barikah Kuni Zuâ€™aimah 
Published: August 2024

Excessive exposure to ultraviolet radiation can cause various skin problems. This problem can be prevented by using cosmetic products that contain sunscreen ingredients. In this study, optimization of the combination of quercetin and avobenzone in sunscreen spray lotion was carried out using the factorial design method.Â The aim of this studyÂ was to determine the optimum concentrations of avobenzone and quercetin which could provide optimum physicochemical properties and effectiveness of in vitro sunscreen spray lotion. The formula is made with a low concentration of 0.5% quercetin and an upper limit of 3%, while avobenzone has a low level of 2% and an upper level of 4%. Based on the research that has been done, the optimum formula prediction is obtained with a concentration of 0.934% quercetin and 4% avobenzone. The optimum formula has a desirability value of 0.958 and shows the predicted value of software to have an SPF in vitro value of 33.311, a %TE 0.058%, a %TP 0.002%, a viscosity of 10 dPa.s, and a pH of 5.689. The results of the analysis using the t-test (one sample t-test) with a 95% level of confidence between the software prediction results and the observation results showed a value of > 0.05, which means that there was no significant difference between the software prediction results and the observation group.
PENGUATAN BUDAYA LITERASI DI MEDIA SOSIAL DALAM PANDANGAN ISLAM
Authors: Muhamad Gunawan , Sainun Sainun , Gazali Gazali 
Published: August 2024

Di era Iptek, penggunaan medsos hampir tidak bisa dibatasi karena sangat cepat melintasi ruang, waktu dan tempat, sehingga ummat Islam semakin dihadapkan dengan berbagai persoalan, baik yang langsung menyentuh ajaran Islam maupun masalah lain yang masih ada kaitannya dengan keislaman dan persoalan itu membutuhkan instrumen penyelesaian dan salah satu instrumen itu adalah ajaran/hukum Islam. Salah satu persoalan yang saat ini marak terjadi adalah penggunaan media sosial untuk menyebarkan hoaks serta ujaran kebencian yang berdampak pada instabilitas nasional, media sosial seperti FB, WA, Instagram, Twiter dan sebagainya yang semakin memudahkan pertemuan di dunia maya. Untuk menjaga agar tidak terjadi hal berdampak negatif pada penggunaan media sosial dibutuhkan budaya literasi untuk semua pengguna medsos tersebut, karena dengan penguatan buadaya literasi maka saya, anda dan kita semua akan mampu memfilter, menyeleksi setiap berita yang disebarkan oleh oran-orang yang tidak bertanggung jawab. Kata Kunci: Penguatan, Budaya Literasi, Media Sosial
Polycythemia Prevalence and Risk Factors in Pilots
Authors: Thanapaisan Patathip , Plaingam Manoj , Manyanont Sorrapong 
Published: August 2024

INTRODUCTION: Pilots are frequently exposed to thrombotic risk as a result of immobility from air travel. As hypoxemia is associated with secondary polycythemia, and polycythemia increases the risk of thrombosis, intermittent exposure to high-altitude hypoxic environments could escalate the risk of thrombosis in pilots. Our objectives were to find the prevalence of polycythemia in airplane pilots (primary outcome) and to assess associated risk factors of polycythemia (secondary outcome).
METHODS: This study is a cross-sectional descriptive study. Data was collected from paper-based and computerized medical records of airplane pilots who applied for Class 1 Aviation Medical Certificate renewal at the Institute of Aviation Medicine, Royal Thai Air Force, Bangkok, Thailand, in 2018. The data was sampled by a simple random sampling technique.
RESULTS: A total of 386 paper-based records were sampled. Of those, 29 (7.5%) of the pilots met polycythemia criteria. Spearman’s correlation analysis showed a significant positive correlation between Body Mass Index (BMI) and hemoglobin (correlation coefficient = 0.127) and between BMI and hematocrit (correlation coefficient = 0.105). In multivariate logistic regression of each variable on polycythemia as defined by hemoglobin alone, piloting a non-pressurized aircraft was found to be an independent predictor of polycythemia (odds ratio = 4.3).
DISCUSSION: The prevalence of polycythemia in airplane pilots was 7.5%. Operating a non-pressurized aircraft was a significant risk factor of polycythemia, and pilots with higher BMI were more likely to have increased red blood cell parameters.
Thanapaisan P, Plaingam M, Manyanont S. Polycythemia prevalence and risk factors in pilots. Aerosp Med Hum Perform. 2024; 95(9):683–687.
Brain and Lung Biomarker Responses to Hyperoxic Hypobaric Decompression
Authors: Connolly Desmond M. , Madden Leigh A. , Edwards Victoria C. , Lee Vivienne M. 
Published: August 2024

INTRODUCTION: Biomarker responses to intensive decompression indicate systemic proinflammatory responses and possible neurological stress. To further investigate responses, 12 additional brain and lung biomarkers were assayed.
METHODS: A total of 15 healthy men (20 to 50 yr) undertook consecutive same-day ascents to 25,000 ft (7620 m), following denitrogenation, breathing 100% oxygen. Venous blood was sampled at baseline (T0), after the second ascent (T8), and next morning (T24). Soluble protein markers of brain and lung insult were analyzed by enzyme-linked immunosorbent assay with plasma microparticles quantified using flow cytometry.
RESULTS: Levels of monocyte chemoattractant protein-1 and high mobility group box protein 1 were elevated at T8, by 36% and 16%, respectively, before returning to baseline. Levels of soluble receptor for advanced glycation end products fell by 8%, recovering by T24. Brain-derived neurotrophic factor rose by 80% over baseline at T24. Monocyte microparticle levels rose by factors of 3.7 at T8 and 2.7 at T24 due to early and late responses in different subjects. Other biomarkers were unaffected or not detected consistently.
DISCUSSION: The elevated biomarkers at T8 suggest a neuroinflammatory response, with later elevation of brain-derived neurotrophic factor at T24 indicating an ongoing neurotrophic response and incomplete recovery. A substantial increase at T8 in the ratio of high mobility group box protein 1 to soluble receptor for advanced glycation end products suggests this axis may mediate the systemic inflammatory response to decompression. The mechanism of neuroinflammation is unclear but elevation of monocyte microparticles and monocyte chemoattractant protein-1 imply a key role for activated monocytes and/or macrophages.
Connolly DM, Madden LA, Edwards VC, Lee VM. Brain and lung biomarker responses to hyperoxic hypobaric decompression. Aerosp Med Hum Perform. 2024; 95(9):667–674.
Clinical Significance of Mottling Rashes in Diving Decompression Sickness
Authors: Breen Ilana D. , Stepanek Jan , Marks Lisa , Yale Katerina , Mesinkovska Natasha , Swanson David 
Published: August 2024

INTRODUCTION: Decompression sickness (DCS) is a medical condition caused by outgassing of dissolved nitrogen following rapid ascent by divers and aviators. Cutaneous DCS, historically termed cutis marmorata (CM), presents as a predominantly truncal reticular violaceous-to-dusky eruption. The prevailing theories for its pathogenesis include: localized cutaneous outgassing, paradoxical embolism across a right-to-left shunt (RLS), and brainstem emboli disrupting autonomic control of cutaneous microcirculation.
METHODS: We conducted a systematic review of reports of cutaneous DCS to investigate relationships among CM, RLS, and neurological sequelae to better elucidate the mechanism of CM. A literature search examining reports of cutaneous DCS yielded 31 eligible studies, comprising a pooled total of 128 patients.
RESULTS: Of the patients with documented workup, 84% showed evidence of RLS with CM. Subsequently 18 patients underwent percutaneous closure of intracardiac RLS with no recurrence of DCS. Of the patients with documented neurological evaluations, 57% experienced both CM and neurological DCS manifestations. The coexistence of RLS and neurological symptoms with CM was noted in numerous cases; exact percentages of overlap cannot be stated due to data unavailability.
DISCUSSION: Our results indicating the striking coexistence of RLS and neurological sequelae in CM patients is supportive of the paradoxical embolism theory of pathogenesis. The frequent coincidence of CM with RLS and neurological symptoms raises concern that CM may signify vulnerability to devastating systemic gas emboli. CM has historically been considered trivial and self-limiting; however, our results support reappraisal of its clinical significance and potential reclassification to the more severe subtype.
Breen ID, Stepanek J, Marks L, Yale K, Mesinkovska N, Swanson D. Clinical significance of mottling rashes in diving decompression sickness. Aerosp Med Hum Perform. 2024; 95(9):695–702.
Pedagogia da alternância e a formação docente para educação no/do campo
Authors: Freitas Vinicius da Silva , Amparo Victor Martins do , Neri Welvis da Cruz , Silva Cícero José da , Silva Júnior Adonias Soares da , Vieira Maurício Aires 
Published: August 2024

O presente estudo pretende mostrar como a Pedagogia da Alternância contribui para a formação docente e como fomenta a atuação deste profissional na educação no campo. A metodologia usada para tal objetivo foi a revisão integrativa da literatura e a abordagem qualitativa da leitura de oito artigos públicados entre 2019-2023. Os fundamentos teóricos foram baseados nas ideias e escritos de em Paulo Freire (2001), Roseli Salete Caldart (2008, 2011, 2012), Jean-Claude Gimonet (2007), Mônica Castagna Molina (2017, 2011), Miguel Arroyo (2011), dentre outros autores que colaboram para o aprofundamento do tema na atualidade. Os resultados apontaram que a Pedagogia da Alternância é uma prática de ensino emancipatória e um tema que vem ganhando destaque ao longo do tempo, pois possibilita que o conhecimento seja contextualizado e aplicado forma dialógica com a vivência coletiva. O que exige o estabelecimento de um novo perfil de educação, sendo a formação docente um componente essencial para a atuação deles na educação do/no campo.
Assessment of the depth of anesthesia with hidden Markov model based on cardiopulmonary variables
Authors: de Rocquigny Gaël , Dubost Clément , Humbert Pierre , Oudre Laurent , Labourdette Christophe , Vayatis Nicolas , Tourtier Jean-Pierre , Vidal Pierre-Paul 
Published: August 2024

BackgroundPrecise monitoring of the Depth of Anesthesia (DoA) is essential to prevent intra-operative awareness (in case of underdosage) or increased post-operative morbi-mortality (in case of overdosage). The recording of a high- frequency multimodal monitoring during general anesthesia (GA) and the capability of classification of dynamic networks should have the potential to help predicting the DoA in a clinical practice. In this study, we aimed at predicting the DoA according four levels (Awake, Loss of Consciousness (LOC), Anesthesia, Return of Consciousness (ROC), Emergence) thanks to a Hidden Markov Model (HMM) relying on four common physiologic variables: Mean Blood Pressure (MBP), Heart Rate (HR), Respiratory Rate (RR), and end-expiratory concentration of sevoflurane (AAEt).MethodsAfter induction by sufentanil and propofol, the anesthesia was maintained by sevoflurane. We recorded the physiological variables at a high frequency during all the procedure [cardiopulmonary variables, AAEt, 2- channel ElectroEncephaloGraphy (EEG) data, and BIS values]. In the training phase, the different states (Awake, LOC, Anesthesia, ROC, Emergence) were identified according to the reading of the spectrograms of the two EEG channels. However, the prediction with the HMM were only based on the four physiological variables.ResultsOn a dataset consisting of 60 patients under general anaesthesia, results suggested that the HMM had a true positive rate (TPR) for identifying Awake, Anesthesia and Emergence of 88%, 72% and 58%, respectively.ConclusionTo our knowledge, this is the first application of such a model to identify the DoA without relying on EEG data. We suggest that a HMM can help the anesthetist monitoring the DoA out of a set of current physiologic variables without necessity of brain monitoring. The model could be improved by increasing the number of patients in the database and accuracy would probably benefit from adding in the model the data of a single EEG channel.
Analysis of miRNAs involved in mouse brain injury upon Coxsackievirus A6 infection
Authors: Sun Yihao , Hao Yilin , Wu Jie , Qian Shasha , Shen Shuo , Yu Yuting 
Published: August 2024

IntroductionCoxsackievirus A6 (CV-A6) has emerged as the predominant epidemic strain responsible for hand, foot and mouth disease (HFMD). CV-A6 infection can result in severe clinical manifestations, including encephalitis, meningitis, and potentially life-threatening central nervous system disorders. Our previous research findings demonstrated that neonatal mice infected with CV-A6 exhibited limb weakness, paralysis, and ultimately succumbed to death. However, the underlying mechanism of CV-A6-induced nervous system injury remains elusive. Numerous reports have highlighted the pivotal role of miRNAs in various viral infections.MethodsSeparately established infection and control groups of mice were used to create miRNA profiles of the brain tissues before and after CV-A6 transfection, followed by experimental verification, prediction, and analysis of the results.ResultsAt 2 days post-infection (dpi), 4 dpi, and 2dpi vs 4dpi, we identified 175, 198 and 78 significantly differentially expressed miRNAs respectively using qRT-PCR for validation purposes. Subsequently, we predicted target genes of these differentially expressed miRNAs and determined their potential targets through GO (Gene Ontology) enrichment analysis and KEGG (Kyoto Encyclopedia of Genes and Genomes) enrichment analysis. Finally, we verified the miRNA-mRNA pairing via double luciferase experiments while confirming functional enrichment of target genes through Western Blotting analyses.DiscussionThe results from this study suggest that transcriptional regulation, neuronal necrosis, pro-inflammatory cytokine release, and antiviral immunity are all implicated in the pathogenesis of central nervous system injury in mice infected with CV-A6. Brain injury resulting from CV-A6 infection may involve multiple pathways, including glial cell activation, neuronal necrosis, synaptic destruction, degenerative diseases of the nervous system. It can even encompass destruction of the blood-brain barrier, leading to central nervous system injury. The dysregulated miRNAs and signaling pathways discovered in this study provide valuable insights for further investigations into the pathogenesis of CV-A6.
Metastatic disease and major adverse cardiovascular events preceding diagnosis are the main determinants of disease-specific survival of pheochromocytoma/paraganglioma: long-term follow-up of 303 patients
Authors: Raber Wolfgang , Schendl Raphael , Arikan Melisa , Scheuba Andreas , Mazal Peter , Stadlmann Valerie , Lehner Reinhard , Zeitlhofer Petra , Baumgartner-Parzer Sabina , Gabler Cornelia , Esterbauer Harald 
Published: August 2024

PurposeThe natural history in unselected cohorts of patients with pheochromocytoma/ paraganglioma (PPGL) followed for a period &gt;10 years remains limited. We aimed to describe baseline characteristics and outcome of a large cohort and to identify predictors of shorter survival.MethodsThis retrospective single-center study included 303 patients with newly diagnosed PPGL from 1968 to December 31, 2023, in 199 prospectively supplemented since July 2020. Mean follow-up was 11.4 (range 0.3-50) years, germline genetic analyses were available in 92.1%. The main outcome measures were overall (OAS), disease-specific (DSS), recurrence-free (RFS) survival and predictors of shorter survival evaluated in patients with metastases at first diagnosis (n=12), metastatic (n=24) and nonmetastatic (n=33) recurrences and without evidence of PPGL after first surgery (n=234).ResultsAge at study begin was 49.4 ± 16.3 years. There were 72 (23.8%) deaths, 15 (5.0%), 29 (9.6%) and 28 (9.2%) due to PPGL, cardiovascular disease (CVD) and malignant or other diseases, respectively. Median OAS, DSS1 (tumor-related) and DSS2 (DSS1 and death caused by CVD) were 4.8, 5.9 and 5.2 years (patients with metastases at first diagnosis), 21.2, 21.2 and 19.9 years, and 38.0, undefined and 38.0 years (patients with metastatic and with nonmetastatic recurrences, respectively). Major adverse cardiovascular events (MACE) preceded the first diagnosis in 15% (n=44). Shorter DSS2 correlated with older age (P ≤ 0.001), male sex (P ≤ 0.02), MACE (P ≤ 0.01) and primary metastases (P&lt;0.0001, also for DSS1).ConclusionThe clinical course of unselected patients with PPGL is rather benign. Survival rates remain high for decades, unless there are MACE before diagnosis or metastatic disease.
Top oil temperature prediction at a multiple time scale for power transformers based on adaptive extended Kalman filter
Authors: Luo Yingting , Wang Lei , Jiang Junfei , Li Duanjiao , Lai Shiyu , Liu Jianming , La Yuan , Sun Wenxing , Shi Mo 
Published: August 2024

To achieve load management optimization and timely failure warning for power transformers, as well as improve the reliability of the power network, this paper proposes a multiple time scale prediction method for top oil temperature (TOT) based on an adaptive extended Kalman filter (AEKF) algorithm. This method combines the Kalman filter (KF) algorithm and the D. Susa thermal model. The TOT, oil exponent and oil time constant are taken as state variables, while the ambient temperature and load current are used as input variables. The iterative optimization of the oil exponent and oil time constant is realized by comparing the estimated and observed TOT values. Moreover, the proposed method utilizes an adaptive noise estimator to correct the noise statistics parameters, which simplifies the initial noise setting and thus further improves the TOT prediction accuracy. A case study is conducted with two 110 kV transformers. The results show that comparing the thermal equivalent circuit model and the extended KF algorithm, the proposed method has a higher accuracy in the intraday ultra-short-term prediction on a 15-min time scale and day-ahead short-term prediction on a 24-h time scale for the TOT.
A model to assess the importance of runway and taxiway particles to aircraft engine compressor deterioration
Authors: Scarso Stefano , Staudacher Stephan , Mathes Jürgen , Schwarz Norman 
Published: August 2024

During service, civil turbofans experience environmentally induced deterioration. Predicting this in a digital service twin model is computationally challenging due to the need to model both deterioration mechanisms and environmental conditions. For compressor erosion, a key challenge is to model particle ingestion throughout a flight mission (FM). During ground operations, these particles may be airborne or deposited on runways and taxiways. This work assesses the impact of the latter on turbofan core compressor deterioration during a mission. The airflow field in front of the engine intake is approximated using potential flow theory. Comparisons with measurements show that the predicted air velocity near the engine is underestimated since the inlet ground vortices generated from viscous effects are neglected. The forces acting on the particles are derived from the flow field. It turns out that most particles are lifted from the ground during take-off (TO). Yet only smaller particles below ≈ 50 µm are ingested into the engine intake. A deterioration model based on flat plate erosion experiments is used to compute mission severity, assuming all particles are similar to medium Arizona Road Dust. The results indicate that the engine’s distance from the ground, power setting, and the number of particles on the ground are key parameters influencing the impact of runway and taxiway particles. Considering the underestimation of the airflow field and thus the number of particles ingested, it is concluded that runway and taxiway particles play a major role in turbofan compressor deterioration.