bluuebunny/crossref_metadata_2025_split huggingface dataset:
Metabolite profiling and network analysis reveal coordinated changes in grapevine water stress response
Authors: Hochberg Uri , Degu Asfaw , Toubiana David , Gendler Tanya , Nikoloski Zoran , Rachmilevitch Shimon , Fait Aaron 
Published: November 2013

AbstractBackgroundGrapevine metabolism in response to water deficit was studied in two cultivars, Shiraz and Cabernet Sauvignon, which were shown to have different hydraulic behaviors (Hochberg et al. Physiol. Plant.147:443–453, 2012).ResultsProgressive water deficit was found to effect changes in leaf water potentials accompanied by metabolic changes. In both cultivars, but more intensively in Shiraz than Cabernet Sauvignon, water deficit caused a shift to higher osmolality and lower C/N ratios, the latter of which was also reflected in marked increases in amino acids, e.g., Pro, Val, Leu, Thr and Trp, reductions of most organic acids, and changes in the phenylpropanoid pathway. PCA analysis showed that changes in primary metabolism were mostly associated with water stress, while diversification of specialized metabolism was mostly linked to the cultivars. In the phloem sap, drought was characterized by higher ABA concentration and major changes in benzoate levels coinciding with lower stomatal conductance and suberinization of vascular bundles. Enhanced suberin biosynthesis in Shiraz was reflected by the higher abundance of sap hydroxybenzoate derivatives. Correlation-based network analysis revealed that compared to Cabernet Sauvignon, Shiraz had considerably larger and highly coordinated stress-related changes, reflected in its increased metabolic network connectivity under stress. Network analysis also highlighted the structural role of major stress related metabolites, e.g., Pro, quercetin and ascorbate, which drastically altered their connectedness in the Shiraz network under water deficit.ConclusionsTaken together, the results showed thatVitis viniferacultivars possess a common metabolic response to water deficit. Central metabolism, and specifically N metabolism, plays a significant role in stress response in vine. At the cultivar level, Cabernet Sauvignon was characterized by milder metabolic perturbations, likely due to a tighter regulation of stomata upon stress induction. Network analysis was successfully implemented to characterize plant stress molecular response and to identify metabolites with a significant structural and biological role in vine stress response.
Direct selective growth of ZnO nanowire arrays from inkjet-printed zinc acetate precursor on a heated substrate
Authors: Kwon Jinhyeong , Hong Sukjoon , Lee Habeom , Yeo Junyeob , Lee Seung S , Ko Seung Hwan 
Published: November 2013

Abstract
Inkjet printing of functional materials has drawn tremendous interest as an alternative to the conventional photolithography-based microelectronics fabrication process development. We introduce direct selective nanowire array growth by inkjet printing of Zn acetate precursor ink patterning and subsequent hydrothermal ZnO local growth without nozzle clogging problem which frequently happens in nanoparticle inkjet printing. The proposed process can directly grow ZnO nanowires in any arbitrary patterned shape, and it is basically very fast, low cost, environmentally benign, and low temperature. Therefore, Zn acetate precursor inkjet printing-based direct nanowire local growth is expected to give extremely high flexibility in nanomaterial patterning for high-performance electronics fabrication especially at the development stage. As a proof of concept of the proposed method, ZnO nanowire network-based field effect transistors and ultraviolet photo-detectors were demonstrated by direct patterned grown ZnO nanowires as active layer.
Isolation of a novel mutant gene for soil-surface rooting in rice (Oryza sativa L.)
Authors: Hanzawa Eiko , Sasaki Kazuhiro , Nagai Shinsei , Obara Mitsuhiro , Fukuta Yoshimichi , Uga Yusaku , Miyao Akio , Hirochika Hirohiko , Higashitani Atsushi , Maekawa Masahiko , Sato Tadashi 
Published: November 2013

Abstract

Background
Root system architecture is an important trait affecting the uptake of nutrients and water by crops. Shallower root systems preferentially take up nutrients from the topsoil and help avoid unfavorable environments in deeper soil layers. We have found a soil-surface rooting mutant from an M2 population that was regenerated from seed calli of a japonica rice cultivar, Nipponbare. In this study, we examined the genetic and physiological characteristics of this mutant.

Results
The primary roots of the mutant showed no gravitropic response from the seedling stage on, whereas the gravitropic response of the shoots was normal. Segregation analyses by using an F2 population derived from a cross between the soil-surface rooting mutant and wild-type Nipponbare indicated that the trait was controlled by a single recessive gene, designated as sor1. Fine mapping by using an F2 population derived from a cross between the mutant and an indica rice cultivar, Kasalath, revealed that sor1 was located within a 136-kb region between the simple sequence repeat markers RM16254 and 2935-6 on the terminal region of the short arm of chromosome 4, where 13 putative open reading frames (ORFs) were found. We sequenced these ORFs and detected a 33-bp deletion in one of them, Os04g0101800. Transgenic plants of the mutant transformed with the genomic fragment carrying the Os04g0101800 sequence from Nipponbare showed normal gravitropic responses and no soil-surface rooting.

Conclusion
These results suggest that sor1, a rice mutant causing soil-surface rooting and altered root gravitropic response, is allelic to Os04g0101800, and that a 33-bp deletion in the coding region of this gene causes the mutant phenotypes.
Dynamic Rheological Properties of Sodium Pyrophosphate-Modified Bentonite Suspensions for Liquefaction Mitigation
Authors: Yoon Jisuk , El Mohtar Chadi 
Published: November 2013

AbstractThe delivery of plastic fines such as bentonite into loose saturated granular soil deposits is an effective method for mitigating the liquefaction phenomenon. While the bentonite should be injected into the deposits in the form of a concentrated suspension, such application is limited in practice because of the low mobility of the suspension. The initial mobility of the bentonite suspension should be managed in order to increase the penetration depth. On the other hand, the suspension needs to maintain its thixotropic nature to improve the resistance of the treated soils under cyclic loading over time. The objective of the present study was to investigate the dynamic rheological properties of the bentonite suspensions modified with an ionic additive, sodium pyrophosphate (SPP), to evaluate a possible application of the modified suspensions in mitigation of liquefaction. In the present study, the storage and loss modulus of SPP-modified bentonite suspensions were measured using a strain-sweep (oscillatory shear) technique. Bentonite suspensions with clay contents of 5, 7.5, 10, and 12 wt.% (by total weight of suspension) were tested at various SPP concentrations (0 to 4 wt.% by weight of dry bentonite). The time-dependent behavior of the suspensions was evaluated with a critical storage modulus at various resting times (0 to 480 h). The results showed that the initial critical storage modulus decreased significantly with increasing SPP concentrations, but the reduced critical storage modulus increased gradually with resting times. This initial reduction in critical storage modulus is attributed to a reduction of the inter-aggregated 3-D networks due to the presence of SPP; the amount of 3-D network formed in a suspension governs the critical storage modulus. With time, the networks are formed gradually, resulting in recovery of critical storage modulus. The normalized modulus was degraded more slowly in the modified suspensions than in the unmodified suspensions, which is a desirable property of the suspensions for mitigation of liquefaction.
Circulating 25-Hydroxyvitamin D, IRS1 Variant rs2943641, and Insulin Resistance: Replication of a Gene–Nutrient Interaction in 4 Populations of Different Ancestries
Authors: Zheng Ju-Sheng , Parnell Laurence D , Smith Caren E , Lee Yu-Chi , Jamal-Allial Aziza , Ma Yiyi , Li Duo , Tucker Katherine L , Ordovás José M , Lai Chao-Qiang 
Published: November 2013

Abstract

BACKGROUND
Associations of either insulin receptor substrate 1 (IRS1) variants or circulating 25-hydroxyvitamin D [25(OH)D] with type 2 diabetes (T2D) and insulin resistance (IR) are inconsistent. This study sought to determine whether circulating 25(OH)D modulates the association of a potentially functional variant at IRS1 (rs2943641) with insulin resistance.

METHOD
Interaction between IRS1 rs2943641 and circulating 25(OH)D on homeostasis model assessment for IR (HOMA-IR) was examined in the Boston Puerto Rican Health Study (BPRHS) (n = 1144). Replication was performed in the African-American (n = 1126), non-Hispanic white (n = 1967), and Hispanic (n = 1241) populations of the Multi-Ethnic Study of Atherosclerosis (MESA) with genotypes of 3 IRS1 variants, rs2972144, rs1515104, and rs2673142, which are tag single nucleotide polymorphisms (SNPs) and in strong linkage disequilibrium with rs2943641.

RESULTS
Higher circulating 25(OH)D was associated with lower risk of T2D and IR in BPRHS women homozygous for minor allele rs2943641T. Consistently, in each of 3 MESA populations, HOMA-IR and insulin decreased more evidently with higher circulating 25(OH)D in women of the rs2943641TT genotype than in carriers of the major allele (rs2943641C). Metaanalysis indicated significant and consistent interactions between circulating 25(OH)D and IRS1 variants on HOMA-IR (log transformed) [pooled β = −0.008, 95% CI: −0.016 to −0.001, P interaction = 0.004] and insulin (log transformed) (pooled β = −0.006, 95% CI: −0.011 to −0.002, P interaction = 0.023) in 3065 women of the 4 populations.

CONCLUSIONS
Participants with different genotypes of IRS1 rs2943641 exhibit differential benefit from high circulating 25(OH)D for the reduction of insulin resistance and T2D risk. This gene–nutrient interaction, which appears to be limited to women, warrants further examination in randomized controlled trials of vitamin D supplementation.
Language statistics and individual differences in processing primary metaphors
Authors: Hutchinson Sterling , Louwerse Max 
Published: November 2013

AbstractResearch in cognitive linguistics has emphasized the role of embodiment in metaphor comprehension, with experimental research showing activation of perceptual simulations when processing metaphors. Recent research in conceptual processing has demonstrated that findings attributed to embodied cognition can be explained through language statistics. The current study investigates whether language statistics explain processing of primary metaphors and whether this effect is modified by the gender of the participant. Participants saw word pairs with valence (Experiment 1: good–bad), authority (Experiment 2: doctor–patient), temperature (Experiment 3: hot–cold), or gender (Experiment 4: male–female) connotations. The pairs were presented in either a vertical configuration (X above Y or Y above X) matching the primary metaphors (e.g., HAPPY IS UP, CONTROL IS UP) or a horizontal configuration (X left of Y or Y left of X) not matching the primary metaphors. Even though previous research has argued that primary metaphor processing can best be explained by an embodied cognition account, results demonstrate that statistical linguistic frequencies also explain the response times of the stimulus pairs both in vertical and horizontal configurations, because language has encoded embodied relations. In addition, the effect of the statistical linguistic frequencies was modified by participant gender, with female participants being more sensitive to statistical linguistic context than male participants.
Premature rupture of membranes at term in low risk women: how long should we wait in the “latent phase”?
Authors: Pintucci Armando , Meregalli Virginio , Colombo Paolo , Fiorilli Angelo 
Published: November 2013

Abstract

Aim: How long the waiting time may be for the onset of spontaneous labor after prelabor rupture of fetal membranes at term (tPROM) remains controversial.

Methods: The study is an observational cohort study of 6032 women. All obstetric patients with no obstetric risk factors, other than tPROM, were included. The analysis focused on the onset of labor (spontaneous vs. induction), maternal morbidity [cesarean section (CS) and chorioamnionitis] and neonatal morbidity (suspected infection) related to a policy of waiting for the onset of spontaneous labor within 48 h of tPROM.

Results: tPROM was experienced by 1439 women. A careful clinical management shows a very low rate of clinical chorioamnionitis (2.3%) and neonatal infection rate (2.8%), even after 24 h from tPROM. The overall incidence of CS was 4.5%. Furthermore, a policy of waiting for the onset of spontaneous labor within 48 h of tPROM is associated with a low rate of CS, less than induced labor (OR=1.76; 95% confidence interval 1.03–3.02; P<0.004).

Conclusions: Fetal and/or maternal morbidity in tPROM women may not increase if there is a strict analysis of maternal and or fetal risk factors added to a careful clinical management. Moreover, it may be useful to wait for spontaneous labor in order to enhance the patient’s chance of vaginal delivery.
L'engagement politique des « intellectuels »
Authors: de Mijolla-Mellor Sophie 
Published: November 2013

Les conditions politiques d’un pays peuvent-elles modifier l’exercice de la psychanalyse ? La psychanalyse génère-t-elle chez ceux qui la pratiquent un mode spécifique d’engagement sociopolitique ? La psychanalyse a-t-elle les moyens de penser sa propre relation au politique ? On interroge ici dans un premier temps la perméabilité de la psychanalyse au sociétal et plus spécialement au politique non pas en fonction de la capacité de la psychanalyse à comprendre non les faits politiques eux-mêmes mais à partir de la position qu’elle adopte vis-à-vis d’eux. Dans un second temps, on montre, avec l’exemple de Rousseau et de Robespierre, que le fait de poser la pensée comme un acte lui restitue tout son poids, sa valeur et partant sa responsabilité historique lorsqu’elle devient un instrument de violence politique alors que son projet conscient visait essentiellement la construction du collectif selon des normes éthiques.
Maurice Blanchot, déserter le mythe
Authors: Nioche Claire 
Published: November 2013

Cet article se propose d’éclairer le point d’origine de l’éthique et de la pensée politique chez Maurice Blanchot à travers deux textes phares, L’Écriture du désastre et L’Instant de ma mort . L’effacement ou la destitution du sujet, la pensée de l’impossible (la mort), la sortie du mythe, sont les conditions d’une nouvelle approche de l’énonciation qui commande l’« engagement » de l’intellectuel, comme Blanchot s’en explique dans son article « Les intellectuels en question ».
Rinsing the Extra Corporeal Circuit with a Heparin and Albumin Solution Reduces the Need for Systemic Anticoagulant in Hemodialysis
Authors: Fransson Filip , Kyrk Tobias , Skagerlind Malin , Stegmayr Bernd 
Published: November 2013

Background Systemic anticoagulation during hemodialysis (HD) increases the risk for bleeding complications pre- or post-operatively. Based on the concept of blood-membrane interaction, we developed a heparin-albumin solution to rinse the dialysis circuit before start. The aim of this study was to investigate if this method was a valuable tool for our patients at risk for bleeding complications. Material and methods This retrospective, comparative, quality assessment study included 248 HD in 68 patients; Group1: 178 treatments were performed at patients for risk of bleeding using heparin-albumin-priming and Group 2: 70 acute HD were performed on patients without increased risk of bleeding using a bolus of heparin at start and a continuous infusion of heparin. In Group 1 additional heparin was given upon suspicion of progressive clotting. One L saline contained albumin (1 g/l) and heparin (5000 U/l) used for priming. Excess priming solution was removed by filling the circuit with blood at start of treatment. Results In Group 1, a mean total dose of 2000 U of heparin was given during the HD (18% performed HD without any heparin) and Group 2 used a mean total dose of 5500 U (p<0.001). There was no increased incidence of clotting in Group 1 versus Group 2 compared to standard HD. No bleeding complications were reported during any of the HA-priming treatments. Conclusions Heparin-albumin priming resulted in a reduced total dose of heparin. There was no increased clotting and no incidence of bleeding was reported in either group.
Intraseasonal variability and atmospheric controls on daily dust occurrence frequency over the central and western Sahara during the boreal summer
Authors: Ashpole Ian , Washington Richard 
Published: November 2013

AbstractWe classify satellite‐derived maps of daily dust occurrence frequency over the central and western Sahara (CWS) during the boreal summer in order to identify typical patterns using the neural network based system of self‐organized maps. Resulting dust states vary in terms of the frequency of dust occurrence and its location. The most commonly occurring dust states are those of relatively low dust detection frequency. On days with relatively high dust occurrence, dust tends to favor either a location close to the Algeria‐Mali‐Niger border triple point (TP) or further to the northwest across the western half of the Mali‐Algeria border (MAB). States in which dust is detected at both locations simultaneously are rare. There is a distinct intraseasonal progression in preferred dust location from the TP in the early season to the MAB later in the season. The evolution of dust states reveals a one‐way transition from dust at the TP to dust at the MAB and then to reduced daily dust occurrence frequency. There is a distinct degree of interannual variability in the occurrence frequency of the different states, dominated by the extremes of high and low dust detection frequency. Analysis of climatological composites demonstrates that monsoon surges into the Saharan heat low are associated with days of high dust detection frequency, while a strong Harmattan into the CWS is linked to days with less frequent dust presence. The CWS atmospheric dust budget for June–August is thus strongly linked to the dynamics of the West African monsoon.
Anion channel blockade: Effects upon erythrocyte membrane calcium response
Authors: Eaton John W. , Branda Richard F. , Hadland Christian , Dreher Kenneth 
Published: November 2013

AbstractThe influx of small amounts of calcium into normal human red cells adversely affects cellular metabolism, shape, ion and water content, and deformability. Because restriction of cation (potassium) efflux moderates these deleterious effects of Ca++ influx, we investigated the possibility that inhibition of anion permeability might be similarly beneficial. Human red cells were treated with 4,4′‐diisothiocyano‐2,2′‐stilbene disulfonate (DIDS), which reacts preferentially with external sites on the transmembrane protein, band 3, and specifically inhibits inorganic anion transport. DIDS‐treated and control cells were then exposed to the ionophore A23187 and Ca++. We find that DIDS treatment blocks Ca++‐induced K+ and water loss and diminishes changes in osmotic fragility and cellular elasticity. Furthermore, DIDS reduces the “trapping” of hemoglobin by red cell membranes and increases the apparent affinity of the cell membrane for glyceraldehyde‐3‐phosphate dehydrogenase.
Polycythemia vera in childhood: Case report and review of the literature
Authors: Danish Elizabeth H. , Rasch Cleo A. , Harris John W. 
Published: November 2013

AbstractA patient presented at 5 years of age with polycythemia vera. He subsequently developed splenic infarctions and died at 20 years of age following cerebral hemorrhage and infarctions. Two months before his death, he developed hypertension and had biochemical evidence of primary hyperparathyroidism and possibly pheochromocytoma.Only nine reported childhood cases of polycythemia vera fulfill the criteria of the Polycythemia Vera Study Group. These cases are summarized and the complications discussed. Although none have progressed to myeloid metaplasia or acute leukemia, these patients are at risk of developing thrombo‐hemorrhagic complications; available evidence indicates that they should be managed to keep the hematocrit between 40 and 45%.
Hyperbaric oxygen for blast‐related postconcussion syndrome: Three‐month outcomes
Authors: Cifu David X. , Walker William C. , West Steven L. , Hart Brett B. , Franke Laura Manning , Sima Adam , Graham Carolyn W. , Carne William 
Published: November 2013

ObjectiveMild traumatic brain injury (mTBI) and postconcussion syndrome (PCS) are common among military combatants. Hyperbaric oxygen (HBO2) is a proposed treatment for these conditions, but it has not been rigorously studied. The objective of this study was to determine the effects of HBO2 by 3 months post compression at 2 commonly employed dosing levels to treat PCS; whether specific subgroups may have benefited; and if no overall effect was found, whether benefit is masked by other conditions.MethodsThis randomized, double‐blind, sham‐controlled study was conducted at the Naval Air Station in Pensacola, Florida on 61 male Marines with a history of mTBI and PCS. Intervention consisted of 40 once daily 60‐minute hyperbaric chamber compressions at 2.0 atmospheres absolute (ATA) at 1 of 3 randomly preassigned oxygen fractions, resulting in respective blinded groups with an oxygen‐breathing exposure equivalent to (1) surface air (sham), (2) 100% oxygen at 1.5ATA, or (3) 100% oxygen at 2.0ATA. The main outcome measure was the Rivermead Post‐Concussion Questionnaire‐16 (RPQ‐16) collected before compressions and at 2 later points.ResultsThe interaction of time by intervention group was not significant for improvement on the RPQ‐16. Nor was there evidence of efficacy on the RPQ‐16 for any subgroup. No significant time by intervention interaction was found for any functional, cognitive, or psychomotor secondary outcome measure at an unadjusted 0.05 significance level.InterpretationUsing a randomized control trial design and analysis including a sham, results showed no evidence of efficacy by 3 months post‐compression to treat the symptomatic, cognitive, or behavioral sequelae of PCS after combat‐related mTBI. ANN NEUROL 2014;75:277–286
Pulsed‐EPR Evidence of a Manganese(II) Hydroxycarbonyl Intermediate in the Electrocatalytic Reduction of Carbon Dioxide by a Manganese Bipyridyl Derivative
Authors: Bourrez Marc , Orio Maylis , Molton Florian , Vezin Hervé , Duboc Carole , Deronzier Alain , Chardon‐Noblat Sylvie 
Published: November 2013

AbstractA key intermediate in the electroconversion of carbon dioxide to carbon monoxide, catalyzed by a manganese tris(carbonyl) complex, is characterized. Different catalytic pathways and their potential reaction mechanisms are investigated using a large range of experimental and computational techniques. Sophisticated spectroscopic methods including UV/Vis absorption and pulsed‐EPR techniques (2P‐ESEEM and HYSCORE) were combined together with DFT calculations to successfully identify a key intermediate in the catalytic cycle of CO2 reduction. The results directly show the formation of a metal–carboxylic acid–CO2 adduct after oxidative addition of CO2 and H+ to a Mn0 carbonyl dimer, an unexpected intermediate.