bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of the Psychometric Properties of the Icelandic Version of the Clinical Outcomes in Routine Evaluation–Outcome Measure, its Transdiagnostic Utility and Cross‐Cultural Validation
Authors: Kristjánsdóttir Hafrún , Sigurðsson Baldur Heiðar , Salkovskis Paul , Ólason Daníel , Sigurdsson Engilbert , Evans Chris , Gylfadóttir Eva Dögg , Sigurðsson Jón Friðrik 
Published: October 2013

BackgroundThe development of transdiagnostic standardized measures of psychological distress have contributed to the development of practice‐based evidence networks. The translation and validation of such measures cross culturally is important if such research is to be generalized across health care systems in different countries.MethodTranslation of the Clinical Outcomes in Routine Evaluation–Outcome Measure (CORE‐OM) from English into Icelandic was undertaken according to recommended protocols. The resulting instrument was evaluated for reliability and validity in three groups: patients undergoing psychological treatment in general practice (n = 289), psychiatric outpatients (n = 98) and student controls (n = 207). The Mini‐International Neuropsychiatric Interview was administered to the clinical participants. They also completed the CORE‐OM and the Beck depression and anxiety inventories before and after treatment. The transdiagnostic relationship between CORE‐OM scores and scores on those diagnostic measures was assessed.ResultsGood levels of validity, reliability and internal consistency were found for the CORE‐OM and its domains and sensitivity to change over treatment shown. As anticipated, the risk domain had different characteristics than other domains. CORE‐OM scores correlated strongly with both Beck Depression Inventory–Second edition and Beck Anxiety Inventory, particularly the problem domain.ConclusionThe Icelandic translation of the CORE‐OM is psychometrically sound and can be applied in Icelandic mental health studies as it has been in English speaking settings. Nevertheless, the validity of the Icelandic version of the CORE‐OM needs to be further investigated in larger and more diverse samples. Copyright © 2013 John Wiley & Sons, Ltd.Key Practitioner Message

The psychometric properties of the Icelandic version of the CORE‐OM are comparable with the original English version.
The results indicate transdiagnostic utility of the CORE‐OM.
The CORE‐OM is a valuable instrument in outcome research on psychological treatment, specifically transdiagnostic treatment.
Over‐evaluation of thoughts about food: Differences across eating‐disorder subtypes and a preliminary examination of treatment effects
Authors: Coelho Jennifer S. , Wilson Samantha , Winslade Amanda , Thaler Lea , Israel Mimi , Steiger Howard 
Published: October 2013

ABSTRACTObjectiveOver‐evaluation of food, shape and weight is a multi‐faceted component of cognitive‐behavioral models of eating disorders. One specific aspect of over‐evaluation of food is a cognitive distortion known as thought‐shape fusion (TSF). TSF is purported to be specific to eating pathology; however, research has not yet elucidated whether individuals across the subtypes of eating disorders are differentially susceptible to this phenomenon. Furthermore, it remains unclear whether susceptibility to TSF decreases over the course of treatment.MethodTSF, eating pathology, and generalized psychopathology were assessed in 76 individuals with eating disorders. Changes in TSF from pre‐ to post‐treatment were assessed in a subset of participants (n = 24).ResultsIndividuals with the binge/purge subtype of anorexia nervosa were more susceptible to TSF than were individuals with bulimia nervosa or the restrictive subtype of anorexia nervosa. Increased TSF corresponded with higher levels of eating pathology, depression, and impulsivity. In addition, there were decreases in TSF over the course of treatment.DiscussionThe observed differences in TSF susceptibility across eating disorder subtypes suggests that subtypes may be differentially prone to over‐evaluation of thoughts about food, which represents a facet of one of the core maintenance mechanisms in cognitive‐behavioral models of eating disorders. © 2013 Wiley Periodicals, Inc. (Int J Eat Disord 2014; 47:302–309)
Riparian vegetation after dam construction on mountain rivers in China
Authors: Sun Rong , Deng Wei‐qiong , Yuan Xing‐zhong , Liu Hong , Zhang Yue‐wei 
Published: October 2013

ABSTRACTIn order to know the change and the response mechanism of riparian vegetation to hydroelectric dams, three diversion‐type stations on the following mountain rivers, Manyue River, Xiaoyuan River and Baili River, were studied. Plants were investigated in consecutive 1 m2 along three separate 12‐m‐long belt transects that were selected along every 100 m upstream and downstream sections of these rivers. The results showed that, first, 125 plant species that consist of 14 trees, 30 shrubs and 81 herbs in a total of 216 quadrats were recorded. Second, there were significant differences on plant communities (species richness, species cover) amongst rivers, which can also be found in terms of the upstream versus downstream. This suggested that the dams had resulted in changes in riparian plant communities, but differences caused by reservoir were within the natural range of variation found across the rivers. Third, we found the number of some xerophytes and highland plants, such as Cupressus funebris, is significantly increased in downstream of dams and some species that adaptated to tranquil reaches and lakes largely increased in upstream of the dams, such as Azolla imbircata and Polygonum nepalense. This revealed that the construction of dams had changed the riparian habitat, the composition and diversity of riparian plants between downstream and upstream of dams. Integrated operation and management of the whole basin should be taken for the health of river system. Copyright © 2013 John Wiley & Sons, Ltd.
Experimental and Computational Investigation of the 1,3‐Dipolar Cycloaddition of the Ynamide tert‐Butyl N‐Ethynyl‐N‐phenylcarbamate with C‐Carboxymethyl‐N‐phenylnitrilimine
Authors: González Pedro Blas , Chandanshive Jay Zumbar , Fochi Mariafrancesca , Bonini Bianca Flavia , Mazzanti Andrea , Bernardi Luca , Locatelli Erica , Caruana Lorenzo , Monasterolo Claudio , Comes Franchini Mauro 
Published: October 2013

AbstractThe reactivity of the ynamide tert‐butyl N‐ethynyl‐N‐phenylcarbamate (1) in the 1,3‐dipolar cycloaddition (1,3‐DC) with C‐carboxymethyl‐N‐phenylnitrilimine was investigated. This [3+2] cycloaddition affords the 5‐amino pyrazole as a single regioisomer. The obtained cycloadduct has been activated at the 4‐position of the pyrazole ring through bromination and subsequently coupled with a phenyl group under Pd catalysis. A detailed computational study has been performed to fully explain the complete regioselectivity observed.
Use of Rhizobium leguminosarum as a potential biofertilizer for Lactuca sativa and Daucus carota crops
Authors: Flores‐Félix José D. , Menéndez Esther , Rivera Lina P. , Marcos‐García Marta , Martínez‐Hidalgo Pilar , Mateos Pedro F. , Martínez‐Molina Eustoquio , Velázquez Ma de la Encarnación , García‐Fraile Paula , Rivas Raúl 
Published: October 2013

AbstractMicrobial biofertilizers are becoming an effective tool for sustainable agriculture by means of the reduction of the use of chemical fertilizers. However, the knowledge of each specific plant–microorganism interaction is essential for a correct application. In this study, we analyzed the in vitro plant‐growth‐promotion mechanisms of a Rhizobium leguminosarum strain named PEPV16 isolated from Phaseolus vulgaris nodules. This strain was able to produce siderophores and indole acetic acid and to solubilize phosphate. Confocal microscopy showed that this strain was able to colonize the roots of two horticultural crops, Lactuca sativa L. (lettuce) and Daucus carota L. (carrot). Strain PEPV16 was also able to promote the plant growth of both plant species increasing the dry matter of shoots and roots of lettuce and carrots, respectively, as well as to increase the uptake of N and P in the edible parts of both plant species. These data confirmed the suitability of Rhizobium as biofertilizer for nonlegumes.
Spectral assessments of phenotypic differences in spike development during grain filling affected by varying N supply in wheat
Authors: Erdle Klaus , Mistele Bodo , Schmidhalter Urs 
Published: October 2013

AbstractSingle plant traits such as green biomass, spike dry weight, biomass, and nitrogen (N) transfer to grains are important traits for final grain yield. However, methods to assess these traits are laborious and expensive. Spectral reflectance measurements allow researchers to assess cultivar differences of yield‐related plant traits and translocation parameters that are affected by varying amounts of available N. In a field experiment, six high‐yielding wheat cultivars were grown with N supplies of 0, 100, 160, and 220 kg N ha–1. Wheat canopies were observed spectrally throughout the grain‐filling period, and three spectral parameters were calculated. To describe the development of the vegetative plant parts (leaves + culms) and the spikes, plants were sampled four times during grain filling. Dry weights and the relative dry‐matter content were recorded for leaves + culms and spikes. The N status of the plants was assessed by measuring the total N concentration and by calculating the aboveground N uptake. Good correlations were found between spectral indices and single plant traits throughout grain filling but varied with N supply and development stage. The normalized difference vegetation index, NDVI, was strongly affected by the saturation effects of increased N concentration. The red‐edge inflection point, REIP, predicted plant traits withr<?h.3>2values up to 0.98. However, in plants with advanced senescence, the REIP was less efficient in describing plant traits. The NIR‐based index R760/R730was closely related to yield‐related plant traits at early grain filling. Compared to the REIP, the R760/R730index was resistant to strong chlorophyll decays being able to predict plant traits at late grain filling, withr<?h.3>2values of up to 0.92. Spectral reflectance measurements may represent a promising tool to assess phenotypic differences in yield‐related plant traits during grain filling.
Compatibilization Mechanism and Property Improvement of Immiscible Engineering Plastic Blends
Authors: Triantou Marianna I. , Chatzigiannakis Emmanouil M. , Tarantili Petroula A. , Andreopoulos Andreas G. 
Published: October 2013

SummaryIn the present research, poly(acrylonitrile‐butadiene‐styrene)/polycarbonate (ABS/PC) blends were prepared in a twin screw extruder. The morphology and thermal and mechanical characteristics of the obtained products were investigated. Reinforcement of the compatibility of the above systems was attempted by the incorporation of organically modified montmorillonite (OMMT), as well as by the addition of compatibilizer (ABS grafted with maleic anhydride, ABS‐g‐MAH) and the effect on the morphology and properties of ABS/PC blends was evaluated. In addition, the incorporation of OMMT to the compatibilized blends was also examined. Reinforcing with OMMT enhances the miscibility of ABS and PC phases in ABS/PC blends, influences the thermal degradation mechanism and gives the best performance in terms of tensile strength, modulus of elasticity and storage modulus in all the examined blends.
Thermal Properties of Particle Brush Materials: Effect of Polymer Graft Architecture on the Glass Transition Temperature in Polymer‐Grafted Colloidal Systems
Authors: Dang Alei , Hui Chin Ming , Ferebee Rachel , Kubiak Joshua , Li Tiehu , Matyjaszewski Krzysztof , Bockstaller Michael R. 
Published: October 2013

SummaryThe governing parameters controlling the glass transition temperature of polymer‐grafted particle systems are analyzed for the particular case of polystyrene (PS)‐grafted silica colloids in the dense grafting limit. At a given degree of polymerization of surface‐grafted chains the glass transition temperature is found to increase as compared to linear chain polymers of equivalent degree of polymerization. The difference in the glass transition temperature between polymer‐grafted particle systems and their respective linear polymer analogs increases with decreasing degree of polymerization of surface‐grafted chains and levels off at similar plateau values for particle brushes of distinct particle core size. The trend toward increased glass transition temperature is interpreted as a consequence of the increased steric hindrance in polymer‐grafted particles that counteracts the relaxation of surface‐grafted polymer chains. The increase in glass transition temperature is shown to be approximately consistent with the chain conformational regimes that are predicted on the basis of a Daoud‐Cotton type scaling model.
Functional Polyesters
Authors: Raposeiro Inês , Fonseca Manuela , Duarte Ana Paula , Bordado João M. 
Published: October 2013

SummaryThe present work aims to study the development of the production process of functionalized polyesters. By exploring materials produced by biological systems and modifying them by synthesis using renewable resources, a new class of biodegradable and biocompatible polyesters is being developed. The presence of specific functional groups opens up a wide range of possibilities for further modification of the polymer structure, and therefore of the respective final properties. Chemical modification of polyhydroxybutyrate (PHB) was carried out by partial glycolization to reduce the molecular weight. Subsequently esterification with maleic anhydride and glycols was performed to obtain unsaturated polyester backbones (UP). The UP was then blended with styrene and crosslinked with different initiating systems. The commercial PHB used possibly contained specific compounds to stabilize the polymer, which present an inhibitory effect on the radical polymerization. Moreover, characterization of this material and the functionalized products was performed as well as the optimization of the synthesis procedure.
Metallic Nanocatalysts Embedded within pH‐Responsive Polymeric Microgels and Deposition onto Solid Substrates
Authors: Kaliva Maria , Frysali Melani A. , Flouraki Chara , Papoutsakis Lampros , Vamvakaki Maria , Anastasiadis Spiros H. 
Published: October 2013

SummaryPalladium (Pd) and ruthenium (Ru) catalytically active nanoparticles are synthesized using as templates pH‐sensitive microgels based on poly(2‐(diethylamino)ethyl methacrylate), PDEAEMA, and poly(acrylic acid), PAA, respectively. The PDEAEMA and PAA microgel particles are prepared by emulsion copolymerization of a functional monomer with a cross‐linker in the presence of a stabilizer in aqueous media. The incorporation of Pd and Ru nanoparticles within PDEAEMA and PAA is achieved using metal precursors that interact with the amino‐ or carboxyl‐groups of PDEAEMA and PAA, respectively; the metal precursors are subsequently reduced within the microgel to produce the metal nanocatalysts. The attachment of the microgel particles onto glass substrate surfaces, which can potentially be used as the walls of microfluidic reactors, is studied by exploring the Pickering emulsion process. The attached particles are tested for stability and endurance when immersed in pure water for extended periods of time and when rinsed extensively with pure water.
Ramsay hunt syndrome: Clinical characterization of progressive myoclonus ataxia caused by GOSR2 mutation
Authors: van Egmond Martje E. , Verschuuren‐Bemelmans Corien C. , Nibbeling Esther A. , Elting Jan Willem J. , Sival Deborah A. , Brouwer Oebele F. , de Vries Jeroen J. , Kremer Hubertus P. , Sinke Richard J. , Tijssen Marina A. , de Koning Tom J. 
Published: October 2013

ABSTRACTBackgroundRamsay Hunt syndrome (progressive myoclonus ataxia) is a descriptive diagnosis characterized by myoclonus, ataxia, and infrequent seizures. Often the etiology cannot be determined. Recently, a mutation in the GOSR2 gene (c.430G>T, p.Gly144Trp) was reported in 6 patients with childhood‐onset progressive ataxia and myoclonus.MethodsWe evaluated 5 patients with cortical myoclonus, ataxia, and areflexia.ResultsAll 5 patients had the same homozygous mutation in GOSR2. Here we present their clinical and neurophysiological data. Our patients (aged 7‐26 years) all originated from the northern Netherlands and showed a remarkably homogeneous phenotype. Myoclonus and ataxia were relentlessly progressive over the years. Electromyography revealed signs of sensory neuronopathy or anterior horn cell involvement, or both, in all patients with absent reflexes.ConclusionsBased on the presented phenotype, we would advise movement disorder specialists to consider mutation analysis of GOSR2 in patients with Ramsay Hunt syndrome, especially when they also have areflexia. © 2013 International Parkinson and Movement Disorder Society
Altered ceramide acyl chain length and ceramide synthase gene expression in Parkinson's disease
Authors: Abbott Sarah K. , Li Hongyun , Muñoz Sonia Sanz , Knoch Bianca , Batterham Marijka , Murphy Karen E. , Halliday Glenda M. , Garner Brett 
Published: October 2013

ABSTRACTGenetic studies have provided increasing evidence that ceramide homeostasis plays a role in neurodegenerative diseases including Parkinson's disease (PD). It is known that the relative amounts of different ceramide molecular species, as defined by their fatty acyl chain length, regulate ceramide function in lipid membranes and in signaling pathways. In the present study we used a comprehensive sphingolipidomic case‐control approach to determine the effects of PD on ceramide composition in postmortem brain tissue from the anterior cingulate cortex (a region with significant PD pathology) and the occipital cortex (spared in PD), also assessing mRNA expression of the major ceramide synthase genes that regulate ceramide acyl chain composition in the same tissue using quantitative PCR. In PD anterior cingulate cortex but not occipital cortex, total ceramide and sphingomyelin levels were reduced from control levels by 53% (P < 0.001) and 42% (P < 0.001), respectively. Of the 13 ceramide and 15 sphingomyelin molecular lipid species identified and quantified, there was a significant shift in the ceramide acyl chain composition toward shorter acyl chain length in the PD anterior cingulate cortex. This PD‐associated change in ceramide acyl chain composition was accompanied by an upregulation of ceramide synthase‐1 gene expression, which we consider may represent a response to reduced ceramide levels. These data suggest a significant shift in ceramide function in lipid membranes and signaling pathways occurs in regions with PD pathology. Identifying the regulatory mechanisms precipitating this change may provide novel targets for future therapeutics. © 2013 International Parkinson and Movement Disorder Society
PBMCs reflect the immune component of the WAT transcriptome—Implications as biomarkers of metabolic health in the postprandial state
Authors: O'Grada Colm M. , Morine Melissa J. , Morris Ciara , Ryan Miriam , Dillon Eugene T. , Walsh Marianne , Gibney Eileen R. , Brennan Lorraine , Gibney Michael J. , Roche Helen M. 
Published: October 2013

ScopeFood and nutrition studies often require accessing metabolically active tissues, including adipose tissue. This can involve invasive biopsy procedures that can be a limiting factor in study design. In contrast, peripheral blood mononuclear cells (PBMCs) are a population of circulating immune cells that are easily accessible through venipuncture. As transcriptomics is of growing importance in food and metabolism research, understanding the transcriptomic relationship between these tissue types can provide insight into the utility of PBMCs in this field.Methods and resultsWe examine this relationship within eight subjects, in two postprandial states (following oral lipid tolerance test and oral glucose tolerance test). Multivariate analysis techniques were used to examine variation between tissues, samples, and subjects in order to define which genes havecommon/disparate expression profiles associated with highly defined metabolic phenotypes. We demonstrate global similarities in gene expression between PBMCs and white adipose tissue, irrespective of the metabolic challenge type. Closer examination of individual genes revealed this similarity to be strongest in pathways related to immune response/inflammation. Notably, the expression of metabolism‐related nuclear receptors, including PPARs, LXR, etc. was discordant between tissuesConclusionThe PBMC transcriptome may therefore provide a unique insight into the inflammatory component of metabolic health, as opposed to directly reflecting the metabolic component of the adipose tissue transcriptome.
Outcome of Patients with Esophageal Perforations: A Multicenter Study
Authors: Biancari Fausto , Saarnio Juha , Mennander Ari , Hypén Linda , Salminen Paulina , Kuttila Kari , Victorzon Mikael , Böckelman Camilla , Tarantino Enrico , Tiffet Olivier , Koivukangas Vesa , Søreide Jon Arne , Viste Asgaut , Bonavina Luigi , Vidarsdóttir Halla , Gudbjartsson Tomas 
Published: October 2013

AbstractBackgroundRecent studies have suggested that stent‐grafting may improve the treatment outcome of patients with esophageal perforation, but evidence on this is still lacking.MethodsData on 194 patients who underwent conservative (43 patients), endoclip (4 patients) stent‐grafting (63 patients) or surgical treatment (84 patients) for esophageal perforation were retrieved from nine medical centers.ResultsIn‐hospital/30‐day mortality was 17.5 %. Three‐year survival was 67.1 %. Age, coronary artery disease, and esophageal malignancy were independent predictors of early mortality. Chi squared automatic interaction detection analysis showed that patients without coronary artery disease, without esophageal malignancy and younger than 70 years had the lowest early mortality (4.1 %). Surgery was associated with slightly lower early mortality (conservative 23.3, endoclips 25.0 %, stent‐grafting 19.0 %, surgery 13.1 %; p = 0.499). One center reported a series of more than 20 patients treated with stent‐grafting which achieved an early mortality of 7.7 % (2/26 patients). Stent‐grafting was associated with better survival with salvaged esophagus (conservative 76.7 %, endoclips 75.0 %, stent‐grafting 77.8 %, surgery 56.0 %; p = 0.019). Propensity score adjusted analysis showed that stent‐grafting achieved similar early mortality (p = 0.946), but significantly higher survival with salvaged esophagus than with surgical treatment (p = 0.001, OR 0.253, 95 % CI 0.110–0.585). Primary surgical repair was associated with somewhat lower early mortality (14.6 vs. 19.0 %; p = 0.561) and better survival with salvaged esophagus (85.4 vs. 77.8 %; p = 0.337) than stent‐grafting.ConclusionsEsophageal perforation was associated with a rather high mortality rate in this all‐comers population. Stent‐grafting failed to decrease operative mortality, but it improved survival with salvaged esophagus. The results of one of the centers indicate that increasing experience with this less invasive procedure may possibly improve the outcome of these patients.