bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prediction of Left Ventricle Pressure Indices Via a Machine Learning Approach Combining ECG, Pulse Oximetry, and Cardiac Sounds: a Preclinical Feasibility Study
Authors: Fassina Lorenzo , Muzio Francesco Paolo Lo , Berboth Leonhard , Ötvös Jens , Faragli Alessandro , Alogna Alessio 
Published: July 2024

AbstractHeart failure (HF) is defined as the inability of the heart to meet body oxygen demand requiring an elevation in left ventricular filling pressures (LVP) to compensate. LVP increase can be assessed in the cardiac catheterization laboratory, but this procedure is invasive and time-consuming to the extent that physicians rather rely on non-invasive diagnostic tools. In this work, we assess the feasibility to develop a novel machine-learning (ML) approach to predict clinically relevant LVP indices. Synchronized invasive (pressure–volume tracings) and non-invasive signals (ECG, pulse oximetry, and cardiac sounds) were collected from anesthetized, closed-chest Göttingen minipigs. Animals were either healthy or had HF with reduced ejection fraction and circa 500 heartbeats were included in the analysis for each animal. The ML algorithm showed excellent prediction of LVP indices estimating, for instance, the end-diastolic pressure with a R2 of 0.955. This novel ML algorithm could assist clinicians in the care of HF patients.
Graphical Abstract
First case report of intestinal lymphangiectasia with refractory bleeding from the duodenum, successfully treated by intra-abdominal lymphaticovenous anastomosis with venous ligation
Authors: Miyakawa Yu , Ihara Sozaburo , Ishii Saaya , Rui Yang , Yajima Shoh , Hayakawa Yoku , Tsuji Yosuke , Okazaki Mutsumi , Seto Yasuyuki , Fujishiro Mitsuhiro 
Published: July 2024

AbstractIntestinal lymphangiectasia (IL) is a protein-losing enteropathy (PLE) that occasionally leads to gastrointestinal bleeding (GIB). We encountered a 41-year-old female with a 9-year history of duodenal IL with PLE and GIB that progressively worsened. Despite a diet, supplemented with medium-chain triglycerides, antiplasmin therapy, oral corticosteroids, octreotides, sirolimus, and repeated endoscopic hemostasis, her symptoms remained uncontrolled, leading to blood transfusion dependence. Lymphangiography revealed significant leakage from abnormal abdominal lymph vessels into the duodenal lumen. The patient subsequently underwent an abdominal-level lymphaticovenous anastomosis combined with local venous ligation. This approach resulted in a dramatic improvement and sustained resolution of both the PLE and GIB. More than 6 months after surgery, the patient remained free of symptoms and blood transfusion dependence.
Association of residual ductal carcinoma in situ with breast cancer treatment outcomes after neoadjuvant chemotherapy according to hormone receptor status
Authors: Shin Eunju , Yoo Tae-Kyung , Kim Jisun , Chung Il Yong , Ko Beom Seok , Kim Hee Jeong , Lee Jong Won , Son Byung Ho , Lee Sae Byul 
Published: July 2024

Abstract
Purpose
This research aimed to clarify the impact of residual ductal carcinoma in situ(DCIS) in surgical specimens obtained after neoadjuvant chemotherapy(NAC) for breast cancer on the associated prognosis outcomes.

Methods
This retrospective study was performed on a cohort of 1,009 patients who achieved pCR following NAC for breast cancer and underwent subsequent breast surgery at a single institution between January 2008 and December 2019. Overall survival, local recurrence-free survival, distant metastasis-free survival, and disease-free survival of the residual and non-residual DCIS groups were the outcomes compared, with further subgroup analysis performed according to hormone receptor status.

Results
260 individuals (25.8%) presented with residual DCIS. Based on a median follow-up of 54.0 months, no significant differences in outcomes were observed between the two groups. Patients with residual DCIS and hormone receptor-negative (HR-) breast cancer demonstrated a significant decrease in distant metastasis-free survival (p = 0.030) compared to those without residual DCIS. In the HR + cohort, no significant difference was observed between the two groups. Multivariate analysis of the HR- cohort demonstrated a significant association between residual DCIS and an elevated risk for distant recurrence (hazard ratio = 2.3, 95% confidence interval = 1.01–5.20, p = 0.047).

Conclusions
Residual DCIS following NAC may impact breast cancer outcomes, particularly with respect to the occurrence of distant metastasis in HR- patients. Therefore, clinicians must vigilantly monitor patients with residual DCIS after NAC, and further research is needed to expand our understanding of the clinical implications of residual DCIS.
Social Processes of Public Sector Collaborations in Kenya: Unpacking Challenges of Realising Joint Actions in Public Administration
Authors: Onyango Gedion 
Published: July 2024

AbstractSocial processes behind the success or failure of collaborative implementation frameworks in African public administration contexts are under-researched. This paper addresses this gap by paying particular attention to trust attributes in collaborative implementation arrangements in Kenya. It shows how implementation challenges of policy programs and interventions may be linked to these interventions’ social characteristics in the public sector. The paper draws on a threefold approach of mutual trust and administrative data on public sector collaborative implementation arrangements for Kenyan anti-corruption policy like the Kenya Leadership Integrity Forum. Findings show that despite increased efforts to realise joint actions in public sector collaborative arrangements, they remain primarily symbolic and hierarchical and feature loose social cohesion among actors, producing challenges bordering on deficiencies in social processes of implementation. These include politicised aloofness or lack of commitment, unclear governance structures, coordination deficiencies, inter-agency conflicts, layered fragmentations, and overlapping competencies among different agencies. The paper recommends identifying and nurturing socially sensitive strategies embedded in mutual trust, like informal knowledge-sharing channels, to address primarily mandated public sector collaboration challenges in Kenya. Such efforts should consider systematic training and incentivising public managers to think outside inward-looking organisational cultures, allowing them to devise sustainable collaborative implementation approaches (promote open innovation) for policy programs, particularly anti-corruption policy.
Mechanistic in silico explorations of the immunogenic and synergistic effects of radiotherapy and immunotherapy: a critical review
Authors: Ng Allison M. , MacKinnon Kelly M. , Cook Alistair A. , D’Alonzo Rebecca A. , Rowshanfarzad Pejman , Nowak Anna K. , Gill Suki , Ebert Martin A. 
Published: July 2024

AbstractImmunotherapy is a rapidly evolving field, with many models attempting to describe its impact on the immune system, especially when paired with radiotherapy. Tumor response to this combination involves a complex spatiotemporal dynamic which makes either clinical or pre-clinical in vivo investigation across the resulting extensive solution space extremely difficult. In this review, several in silico models of the interaction between radiotherapy, immunotherapy, and the patient’s immune system are examined. The study included only mathematical models published in English that investigated the effects of radiotherapy on the immune system, or the effect of immuno-radiotherapy with immune checkpoint inhibitors. The findings indicate that treatment efficacy was predicted to improve when both radiotherapy and immunotherapy were administered, compared to radiotherapy or immunotherapy alone. However, the models do not agree on the optimal schedule and fractionation of radiotherapy and immunotherapy. This corresponds to relevant clinical trials, which report an improved treatment efficacy with combination therapy, however, the optimal scheduling varies between clinical trials. This discrepancy between the models can be attributed to the variation in model approach and the specific cancer types modeled, making the determination of the optimum general treatment schedule and model challenging. Further research needs to be conducted with similar data sets to evaluate the best model and treatment schedule for a specific cancer type and stage.
Application of the artificial neural network and enhanced particle swarm optimization to model updating of structures
Authors: Kao Ching-Yun , Hung Shih-Lin , Xu Pei-Jia 
Published: July 2024

Abstract
An efficient and accurate two-stage approach, based on the artificial neural network (ANN) and an enhanced particle swarm optimization (EPSO) approach for model updating of structures using incomplete measurements, is proposed in this study. The first stage, preliminary model updating, employs the ANN to quickly learn the mapping relationship between the natural frequencies and stiffness of the structure using a few training, validation, and testing instances. The inputs and outputs of the ANN are the natural frequencies and stiffness of the structure, respectively. The ANN’s training, validation, and testing instances are extracted through Latin hypercube sampling. The ANN-predicted stiffness provides an excellent basis for determining and reducing the search space of the optimal stiffness in the second stage. The second stage, detailed model updating, searches for the optimal stiffness of the structure by using the EPSO approach. The EPSO approach improves particle swarm optimization (PSO) by employing an elite crossover strategy to avoid trapping in the local optimum and premature convergence. The feasibility and effectiveness of the proposed two-stage approach for stiffness updating of shear building structures using incomplete measurements are demonstrated by numerical and experimental examples. The results present that the proposed two-stage approach improves the computational efficiency and solution quality of the GA (Genetic Algorithm) and PSO for stiffness updating of shear building structures.
Exploring the biotechnological prospects of a recently discovered fungus isolated from marine mucilage
Authors: Bayazıt Gizem , Gül Ülküye Dudu , Taştan Burcu Ertit , Tozoğlu Fatih , Gurbanov Rafig 
Published: July 2024

AbstractThis study aimed to determine the usability of the identified fungus isolated from the marine-mucilage formation in the biotechnological processes. For this purpose, the antimicrobial and antioxidant activities of the extract obtained from the fungus were examined, and the fatty acid methyl ester composition was determined. The molecular identification of the pure fungal culture was made using LSU regions. In addition, fungal extracts were prepared using different solvents, and the antimicrobial activity of these extracts was investigated by disk diffusion and minimum inhibition concentration methods. At the same time, the antioxidant properties of these extracts were analyzed using the DPPH and ABTS free radical removal methods. Also, FAME analysis was performed to determine the fatty acid content of the fungal extract. According to the study results, the new isolate was identified as the fungus Rhizopus stolonifer. Although fungal extracts have no significant antimicrobial activity, it has been determined that they performed successful DPPH and ABTS scavenging activity without needing additional reactions. FAME results indicate that the mucilage-originated fungus R. stolonifer is a valuable provider of fatty acids that, when purified at large bioreactors, can be good and cheap sources of next-generation biologicals for wide-ranging biotechnological applications.
Investigating the influence of e-navigation and S-100 over the computation of the weather route
Authors: Palma Valentino , Giglio Davide , Tei Alessio 
Published: July 2024

AbstractThe weather route presents significant potential in identifying the most efficient route for vessels, enabling the optimisation of distance, time, or fuel consumption. Although there have been notable advancements in most technologies in recent years, weather routing has failed to keep pace with these developments. The purpose of this document is to determine whether a specific IMO’s concept called e-navigation may have an impact on vessel’s route optimisation. Today, mariners are required to integrate heterogeneous data types (hydrographic, weather, oceanographic, etc.) that are transmitted on board via various devices and in diverse formats in order to execute weather routing. When e-navigation becomes operational, relevant marine-related data will be accessible in a standardised format on a unified device. The objective of this work is to examine the potential of S-100 in the context of weather routing and route optimisation for the benefit of navigation. There are two methodologies discussed: manual and automated. A range of S-100-based products will be evaluated in relation to a variety of optimisation algorithms in order to predict whether e-navigation could be advantageous in addressing the weather routing problem. Constraints regarding the implementation of electronic navigation and the mariners’ duties are outlined in the final part of the paper.
Non-destructive characterization of resistance projection welded joints by ultrasonic and passive magnetic flux density testing
Authors: Mathiszik Christian , Koal Johannes , Zschetzsche Jörg , Füssel Uwe , Schmale Hans Christian 
Published: July 2024

AbstractThe weld of resistance projection welded joints is not visible from outside. Therefore, visual evaluation is restricted, and visual inspection is not possible at all. So far, the parameters of the welding process are monitored and controlled. In addition, the welds are periodically tested destructively to determine the quality of the welds. No industrial standard has yet been established in the field of non-destructive testing (NDT) for projection welded joints. This study focuses on NDT of projection welds using two different ultrasonic imaging inspection systems and the passive magnetic ux density testing (pMFT) method. The ultrasonic inspection systems commercially available and established in the field of NDT of spot welds. Both systems are originally designed for the NDT of spot welds and not for projection welds. Unlike the ultrasonic systems, the pMFT is still in laboratory status. The method has originally been developed to evaluate spot welds and is also used in this study to evaluate projection welds. The applicability of the investigated systems to projection welding is investigated in order to derive mandatory development steps to achieve reliable results. The pMFT method shows also good results for NDT of spot welds In this contribution, the measurement and evaluation concept of the three NDT systems for projection welded joints is presented. The NDT results are discussed in the context of the corresponding destructive results in terms of tensile forces and fracture areas. Advises for further development of all investigated systems are given.
Liquid Metal Grid Patterned Thin Film Devices Toward Absorption-Dominant and Strain-Tunable Electromagnetic Interference Shielding
Authors: Wei Yuwen , Bhuyan Priyanuj , Kwon Suk Jin , Kim Sihyun , Bae Yejin , Singh Mukesh , Thanh Tran Duy , Ha Minjeong , Jeong Kwang-Un , Ma Xing , Park Byeongjin , Park Sungjune 
Published: July 2024

AbstractThe demand of high-performance thin-film-shaped deformable electromagnetic interference (EMI) shielding devices is increasing for the next generation of wearable and miniaturized soft electronics. Although highly reflective conductive materials can effectively shield EMI, they prevent deformation of the devices owing to rigidity and generate secondary electromagnetic pollution simultaneously. Herein, soft and stretchable EMI shielding thin film devices with absorption-dominant EMI shielding behavior is presented. The devices consist of liquid metal (LM) layer and LM grid-patterned layer separated by a thin elastomeric film, fabricated by leveraging superior adhesion of aerosol-deposited LM on elastomer. The devices demonstrate high electromagnetic shielding effectiveness (SE) (SET of up to 75 dB) with low reflectance (SER of 1.5 dB at the resonant frequency) owing to EMI absorption induced by multiple internal reflection generated in the LM grid architectures. Remarkably, the excellent stretchability of the LM-based devices facilitates tunable EMI shielding abilities through grid space adjustment upon strain (resonant frequency shift from 81.3 to 71.3 GHz @ 33% strain) and is also capable of retaining shielding effectiveness even after multiple strain cycles. This newly explored device presents an advanced paradigm for powerful EMI shielding performance for next-generation smart electronics.
Multispecialty resident physicians’ perceived preparedness for mass casualty events (MCEs) at an urban level I trauma center prior to the coronavirus disease 2019 (COVID-19) era
Authors: Voza Francesca A. , Gupta Aakansha , Rossen Noah , An Anjile , Easthausen Imaani , Christos Paul J. , Winchell Robert J. , Barie Philip S. , Narayan Mayur 
Published: July 2024

Abstract
Purpose
Coronavirus disease 2019 (COVID-19) has underscored how ill-prepared healthcare systems are for mass casualty events (MCEs,) especially as MCEs increase worldwide. We hypothesized that resident physicians (RPs) across multiple specialties are underprepared for MCE.

Methods
Two similar surveys were conducted to assess awareness of disaster plans (DPs) and individual’s roles and responsibilities therein. Initially, we surveyed exclusively trainees who are trauma team members (TTMs,) including physician assistants (PAs), residents from emergency medicine (EMRs) and general surgery (GSRs.) Subsequently, we surveyed multi-specialty RPs, except GSRs and EMRs, and their program directors/associate program directors (PDs/APDs.) RPs’ awareness, knowledge of, and confidence in hospital MCE response plans were assessed, and barriers encountered were queried. Data were consolidated except with respect to PDs/APDs, who were queried only in the second survey. The Fisher exact test for multiple-group comparisons was used. Alpha = 0.05.

Results
For the first survey, the response rate was 74% (123/166), whereas 34% (129/380) responded to the second survey. Combined, the response rate was 46% (252/546.) Considering the RPs only for the two surveys combined, 103 (53%) respondents reported no awareness of institutional MCE response plans, 73% (n = 143) did not know/were unsure whether they were expected to contact someone, and 68% (n = 134) reported no formal MCE/disaster management (DM) training over the prior year. Additionally, the median response reported for level of knowledge of the MCE response plan among all RPs was “not at all,” with a significant difference observed between those aware of the plan and those who were not (p < 0.001). The median response reported for confidence level of RPs in MCE/DM training, excluding GSRs and EMRs (TTMs,) was “not at all,” with significant differences between surgical and non-surgical specialty RPs (p = 0.031), and between junior and senior RPs (p = 0.027). PDs/APDs (n = 12) reported “time” as the main barrier to implementation.

Conclusions
RPs across all surveyed specialties reported low levels of knowledge and minimal training regarding MCE/DM. Incorporation of MCE/DM preparedness into residency training in all specialties involving direct patient care is essential. Curricular restructuring will be required for meaningful participation of RPs in MCEs.
Tidal dynamic response to riverbed evolution in the Yangtze River Estuary
Authors: Han Yufang , Dai Bingke , Ding Hongwei 
Published: July 2024

AbstractSince 1958, there have been significant changes in the Yangtze River estuary. Due to extensive reclamation and construction of ports and channels, the water area has drastically decreased, resulting in corresponding changes in hydrodynamics and riverbeds at the mouth of the river. According to the analysis of measured topographic data and Delft3D-FLOW model for seven typical historical periods since 1958 at the Yangtze River Estuary, this study investigates the characteristics of riverbed evolution and tidal flow dynamics. From 1958 to 2019, driven by strong human activities, the total area of the Yangtze River Estuary decreased from 2084 km2 to 1403 km2, with a decrease of 32.7%, while the total volume of the corresponding river channel changed slightly and remained stable. Compared with 1958, the volume of the Yangtze River Estuary in 2019 only increased by 345 million m3, with an increase of about 4.1%. The tidal dynamic change of the Yangtze Estuary is closely related to the riverbed evolution of each reach, which not only shapes the estuary landform, but also is affected by the riverbed evolution. Tidal level, tidal range and water area change are closely related. With the decrease of water area in the Yangtze River Estuary, tidal range tends to increase. Tidal prism change is closely related to channel volume. In the past 60 years, the tidal volume at the mouth of the Yangtze River has decreased by 8%. The research findings will provide technical support for enhancing flood control and tide resistance measures at the Yangtze River Estuary, as well as formulating comprehensive management plans for estuaries, contributing to the protection and sustainable development of the Yangtze River Estuary.
Health communication research in the Arab world: a bibliometric analysis
Authors: Bardus Marco , Kabakian-Khasholian Tamar , Kanj Mayada 
Published: July 2024

Abstract
Introduction
A recent bibliometric analysis of health communication research in the Arab world identified 66 reports since 2004. However, it covered only PubMed and used “health communication” as a unique search phrase. This does not capture Gary Kreps’ five health communication research areas: health promotion, delivery of care, risk communication, eHealth, and healthcare management.

Aims and objectives
To generate a more comprehensive map of health communication research in the Arab world by searching three major bibliographic databases: PubMed, Scopus, and Web of Science (WoS). To undertake a publication and citation analysis comparing countries, authors, institutions, research themes, and publication venues across the databases.

Methods
We developed a sensitive search strategy encompassing health communication-relevant keywords, Medical Subject Headings (MeSH), and a filter to identify the 22 countries of the League of Arab States. We conducted separate searches in PubMed, Scopus, and WoS. We compared search results and publication classifications across the databases. We used Scopus and WoS built-in analytical features to generate data inputted into VOSviewer to undertake citation, co-citation, and co-word analyses to map themes and research areas across databases.

Results
As of May 8, 2024, Searches yielded 518 records in PubMed, 559 in Scopus, 483 in WoS, and 905 unique records across databases. Most research has been conducted in the last 2 years in Saudi Arabia, Jordan, Egypt, the UAE, and Lebanon. Health communication research is multidisciplinary, with a thematic structure representing the recent developments of telemedicine and eHealth during and after the COVID-19 pandemic.

Conclusion
Health communication research in the Arab world has been much broader than depicted before and goes beyond communication sciences. This bibliometric analysis reveals the extensive and diverse landscape of health communication research in the Arab world, emphasising its multidisciplinary nature and laying the groundwork for future studies and policy directions.