bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association of oxidative stress with motor neuron disease in horses
Authors: Mohammed Hussni O. , Divers Thomas J. , Kwak Justin , Omar Adil H. , White Maurice E. , de Lahunta Alexander 
Published: November 2012

Abstract
Objective—To investigate the influence of oxidative stress in terms of antioxidant capacity and lipid peroxidation on the probability of motor neuron disease (MND) in horses.
Animals—88 horses with MND (cases) and 49 controls.
Procedures—Blood samples were collected from all horses enrolled, and RBCs and plasma were harvested. Activity of the enzyme erythrocytic superoxide dismutase 1 (SOD1) was determined in the RBCs. Plasma concentrations of α-tocopherols and β-carotenes and activity of glutathione peroxidase were also evaluated. Degree of lipid peroxidation was measured by determining plasma concentrations of lipid hydroperoxides. Differences were evaluated between horse groups.
Results—Cases had lower erythrocyte SOD1 activity than did controls, but the difference was not significant. On the other hand, plasma vitamin E concentrations differed significantly between groups, with the cases having lower concentrations. Neither plasma vitamin A concentration nor glutathione peroxidase activity differed between groups; however, cases had significantly higher concentrations of lipid hydroperoxides (18.53μM) than did controls (12.35μM).
Conclusions and Clinical Relevance—Horses with MND differed from those without MND by having a lower plasma concentration of vitamin E and higher concentrations of lipid hydroperoxides. Results parallel the findings in humans with sporadic amyotrophic sclerosis and provide evidence supporting the involvement of oxidative stress in the 2 conditions.
Analysis of the transport of and cytotoxic effects for nalbuphine solution in corneal cells
Authors: Spatola Ronald A. , Thangavelu Mirunalni , Upadhyayula Vijayasaradhi , Lee Seungsoo , Phelps Mitch A. , Chandler Heather L. 
Published: November 2012

Abstract
Objective—To assess the in vitro effects of various nalbuphine concentrations on viability and wound healing ability of corneal cells and potential drug transport through the corneal epithelium.
Sample—Cultured canine and human corneal epithelial cells (CECs) and cultured canine corneal stromal fibroblasts.
Procedures—CECs and stromal fibroblasts were exposed to nalbuphine (concentration of solutions ranged from 0% to 1.2%) for up to 30 minutes, and viability was assessed with a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. A standard scratch test technique was used. Wound healing of CECs and stromal fibroblasts was evaluated following treatment with nalbuphine solutions < 0.1%. Liquid chromatography–mass spectrometry–mass spectrometry analysis was used to evaluate drug transport across a monolayer and a multilayer of human CECs.
Results—A progressive decrease in viability was detected in canine CECs for all nalbuphine treatment groups, whereas treatment with only 0.5% or 1.2% nalbuphine significantly reduced corneal stromal fibroblast viability, compared with results for control cells. Within 24 hours, treatment with 0.1% nalbuphine solution significantly altered the healing rate of both canine CECs and stromal fibroblasts. Continuous increases in transport rates of nalbuphine were detected with time for both the monolayer and multilayer of human CECs.
Conclusions and Clinical Relevance—In vitro, nalbuphine potentially could penetrate through corneal tissue, but it may cause damage to the corneal epithelium and stromal fibroblasts. Therefore, nalbuphine potentially may impair corneal wound healing.
Preparation, characterisation, and dielectric properties of polypyrrole-clay composites
Authors: Madakbaş Seyfullah , Çakmakçı Emrah , Kahraman Memet , Esmer Kadir 
Published: November 2012

AbstractIn this study, polypyrrole-clay (PPy-clay) composites were prepared by the in situ chemical oxidative polymerisation of pyrrole in the presence of clay. The chemical structures of the composites were characterised by FTIR and XRD analysis. The thermal properties of these novel composites were analysed by TGA and DSC measurements. Glass-transition temperatures and char yields increased with the increase in clay content in the nanocomposites. The interactions between PPy and clay were mainly between polypyrrole and the layers of clay. It was observed that, as the amount of clay in the composites increased, the dielectric permittivity decreased while the dielectric conductivity of the composite materials increased.
Micelle nano-reactors as mediators of water-insoluble ligand complexation with Cu(II) ions in aqueous medium
Authors: Adıgüzel Ragıp , Taşcıoğlu Senay 
Published: November 2012

AbstractComplexation reactions between water-soluble and -insoluble reactants were shown to occur in aqueous media in the presence of normal or reverse surfactant micelles, in significantly higher yields at lower temperatures compared to those achieved in neat organic solvents. The highest yield enhancement in the complexation of novel water-insoluble bis(2-amino-1,3,4-thiadiazolyl)methane and 1,4-bis(2-amino-1,3,4-thiadiazolyl)benzene ligands with Cu(II) ions was achieved in the sodium bis(2-ethylhexyl)sulfosuccinate (AOT)-heptane-water reverse micellar system at the hydration ratio of 15. The results revealed that AOT normal micelles cause a change in the reaction mechanism together with the enhancement of the complex formation. The observed micellar effects were rationalized on basis of the properties of bulk solvents, surfactants and ligands, considering the solvation and hydration ratios of reverse micelles. The results have proved the dependence of complex yield on the amount and accordingly also on the properties of water in the micellar core, indicating that the yield can be maximized by the optimization of the hydration ratio.
Dynamic shape and wall correction factors of cylindrical particles falling vertically in a Newtonian liquid
Authors: Strnadel Jaroslav , Šiška Bedřich , Machač Ivan 
Published: November 2012

AbstractResults of numerical calculations of dynamic shape and wall correction factors for the flow of a Newtonian fluid over a vertically oriented cylindrical particle in a cylindrical tube are reported. Mathematical model of the flow was solved using the finite element method by means of the COMSOL Multiphysics software. Dependences of the shape factor on the cylinder aspect ratio and of the wall correction factor, F W, on the ratio of the cylindrical particle diameter to the tube diameter, and on the aspect ratio were obtained. Numerical dependences were approximated by simple relationships suitable for dynamic shape and wall correction factors prediction.
Effectiveness of Front-of-pack Nutrition Symbols: A Pilot Study with Consumers
Authors: Emrich Teri E. , Mendoza Julio E. , L’abbé Mary R. 
Published: November 2012

Purpose: The effectiveness of different front-of-pack nutrition rating systems and symbols (FOPS) has not been studied among Canadians. We pilot tested an online FOPS survey with consumers. Methods: Members of the Guelph Food Panel were randomly exposed to traffic light, Percent Daily Value, Health Check, and Smart Pick logos on mock food packages and were asked to rate the FOPS on a Likert-type scale. The FOPS were rated on consumers’ ability to understand them, credibility, and influence on purchase decisions. Participants also provided feedback on the survey. Results: Participants (n=337) deemed the survey appropriate in length and language, and provided suggestions for improving survey clarity. More than 50% of the respondents believed that FOPS should be present on all food packages (65.1%) and should be government regulated (53.0%). The Percent Daily Value symbol was rated highest with respect to liking, credibility, helpfulness, and influence, but was the least understood. When they used direct comparison, consumers preferred the traffic light symbol (53.1%) over the Percent Daily Value (40.0%), Health Check (6.7%), and Smart Pick (0.3%) symbols. Conclusions: The survey was revised as a result of the pilot study feedback. Preliminary findings from this pilot study suggest that consumers prefer a single, government-regulated symbol, and value more complex FOPS, like the Percent Daily Value symbol, despite finding them harder to understand.
Midterm and long-term follow-up of cerebral aneurysms treated with flow diverter devices: a single-center experience
Authors: Piano Mariangela , Valvassori Luca , Quilici Luca , Pero Guglielmo , Boccardi Edoardo 
Published: November 2012

Object
The introduction of flow diverter devices is revolutionizing the endovascular approach to cerebral aneurysms. Midterm and long-term results of angiographic, cross-sectional imaging and clinical follow-up are still lacking. The authors report their experience with endovascular treatment of intracranial aneurysms using both the Pipeline embolization device and Silk stents.

Methods
From October 2008 to July 2011 a consecutive series of 104 intracranial aneurysms in 101 patients (79 female, 22 male; average age 53 years) were treated. Three of the 104 aneurysms were ruptured and 101 were unruptured. Silk stents were implanted in 47 of the aneurysms and Pipeline stents in the remaining 57. In 14 cases a combination of flow diverter devices and coils were used to treat larger aneurysms (maximum diameter > 15 mm).
Patients underwent angiographic follow-up examination at 6 months after treatment, with or without CT or MRI, and at 1 year using CT or MRI, with or without conventional angiography.

Results
In all cases placement of flow diverter stents was technically successful. The mortality and morbidity rates were both 3%. Adverse events without lasting clinical sequelae occurred in 20% of cases. Angiography performed at 6 months after treatment showed complete aneurysm occlusion in 78 of 91 cases (86% of evaluated aneurysms) and subocclusion in 11 (12%); only in 2 cases were the aneurysms unchanged. Fifty-three aneurysms were evaluated at 1 year after treatment. None of these aneurysms showed recanalization, and 1 aneurysm, which was incompletely occluded at the 6-month follow-up examination, was finally occluded. Aneurysmal sac shrinkage was observed in 61% of assessable aneurysms.

Conclusions
Parent artery reconstruction using flow diverter devices is a feasible, safe, and successful technique for the treatment of endovascular treatment of cerebral aneurysms.
Concurrent dural and perimedullary arteriovenous fistulas at the craniocervical junction: case series with special reference to angioarchitecture
Authors: Sato Kenichi , Endo Toshiki , Niizuma Kuniyasu , Fujimura Miki , Inoue Takashi , Shimizu Hiroaki , Tominaga Teiji 
Published: November 2012

Object
Dural arteriovenous fistulas (DAVFs) and perimedullary arteriovenous fistulas (PAVFs) are uncommonly associated in the craniocervical junction. The purpose of this study was to describe the clinical and angiographic characteristics of such concurrent lesions.

Methods
Authors reviewed 9 cases with a coexistent DAVF and PAVF at the craniocervical junction. Clinical presentation, angiographic characteristics, intraoperative findings, and treatment outcomes were assessed.

Results
All patients (male/female ratio 5:4; mean age 66.3 years) presented with subarachnoid hemorrhage. Angiography revealed that 8 patients had both a DAVF and PAVF on the same side, whereas 1 patient had 3 arteriovenous fistulas, 1 DAVF, and 1 PAVF on the right side and 1 DAVF on the left side. All of the fistulas shared dilated perimedullary veins (anterior spinal vein, 7 cases; anterolateral spinal vein, 2 cases) as a main drainage route. The shared drainage route was rostrally directed in 8 of 9 cases. Eight patients exhibited an arterial aneurysm on the distal side of the feeding arteries to the PAVF, and the aneurysm in each case was intraoperatively confirmed as a bleeding point. One patient had ruptured venous ectasia at the perimedullary fistulous point. All patients underwent direct surgery via a posterolateral approach. No recurrence was observed in the 4 patients who underwent postoperative angiography, and no rebleeding event was recorded among any of the 9 patients during the follow-up period (mean 38.4 months).

Conclusions
The similarity of the angioarchitecture and the close anatomical relationship between DAVF and PAVF at the craniocervical junction suggested that these lesions are pathogenetically linked. The pathophysiological mechanism and anatomical features of these lesions represent a unique vascular anomaly that should be recognized angiographically to plan a therapeutic strategy.
The effect of exercise on mobilization of hematopoietic progenitor cells involved in the repair of sciatic nerve crush injury [RETRACTED]
Authors: Cheng Fu-Chou , Sheu Meei-Ling , Su Hong-Lin , Chen Ying-Ju , Chen Chun-Jung , Chiu Wen-Ta , Sheehan Jason , Pan Hung-Chuan 
Published: November 2012

Object
Mobilization of hematopoietic progenitor cells (HPCs) from bone marrow involved in the process of peripheral nerve regeneration occurs mostly through deposits of CD34+ cells. Treadmill exercise, with either differing intensity or duration, has been shown to increase axon regeneration and sprouting, but the effect of mobilization of HPCs on peripheral nerve regeneration due to treadmill exercise has not yet been elucidated.

Methods
Peripheral nerve injury was induced in Sprague-Dawley rats by crushing the left sciatic nerve using a vessel clamp. The animals were categorized into 2 groups: those with and without treadmill exercise (20 m/min for 60 minutes per day for 7 days). Cytospin and flow cytometry were used to determine bone marrow progenitor cell density and distribution. Neurobehavioral analysis, electrophysiological study, and regeneration marker expression were investigated at 1 and 3 weeks after exercise. The accumulation of HPCs, immune cells, and angiogenesis factors in injured nerves was determined. A separate chimeric mice study was conducted to assess CD34+ cell distribution according to treadmill exercise group.

Results
Treadmill exercise significantly promoted nerve regeneration. Increased Schwann cell proliferation, increased neurofilament expression, and decreased Schwann cell apoptosis were observed 7 days after treadmill exercise. Elevated expression of S100 and Luxol fast blue, as well as decreased numbers of vacuoles, were identified in the crushed nerve 3 weeks after treadmill exercise. Significantly increased numbers of mononuclear cells, particularly CD34+ cells, were induced in bone marrow after treadmill exercise. The deposition of CD34+ cells was abolished by bone marrow irradiation. In addition, deposits of CD34+ cells in crushed nerves paralleled the elevated expressions of von Willebrand factor, isolectin B4, and vascular endothelial growth factor.

Conclusions
Bone marrow HPCs, especially CD34+ cells, were able to be mobilized by low-intensity treadmill exercise, and this effect paralleled the significant expression of angiogenesis factors. Treadmill exercise stimulation of HPC mobilization during peripheral nerve regeneration could be used as a therapy in human beings.
L'invention de l'hyperactivité : quand le test confirme la nosographie et vice-versa
Authors: Renard Ursula 
Published: November 2012

Les développements informatiques et biotechnologiques à visée de traitement normatif de l’information ont permis la prédominance des théories cognitives de l’intelligence et des troubles psychiques et donc des thérapies, traitements, et tests. Le développement de la neuro-imagerie associé à l’émergence de traitements psychotropes est venu répondre à l’impératif scientifique de preuves neurologiques. L’invention du déficit attentionnel avec ou sans hyperactivité (TDHA) est né de ce changement de paradigme en un circuit fermé qui exclut totalement le sujet de l’inconscient. De l’enfant hyperactif à l’hyperactivité au TDHA, on se sépare de la psychanalyse et on isole une entité en la nommant : c’est le « stade du miroir » nosographique.
« U corsu » à l'école et dans la rue : entre visibilité, promotion et reflux
Authors: Ottavi Pascal 
Published: November 2012

L’appel à enquête relative au contact des langues lancé en juin 2010 par la DGLFLF a permis l’observation de l’espace langagier corse sur trois terrains différents : des établissements scolaires bilingues, l’espace public, la radio locale de service public. Trois enquêtes ont été réalisées aux mois de novembre et décembre 2010. En école et en collège, malgré un investissement important des enseignants en matière de langue corse, les productions des élèves, en contexte didactique, sont relativement limitées. Dans les productions spontanées, les pairs utilisent généralement un français générationnel teinté d’accent régional et recourent à l’emprunt au corse. Dans l’espace public, à Ajaccio et à Ile-Rousse, les conversations privées révèlent une certaine fréquence de l’emploi du corse, des pratiques dominantes de recours au contact des langues, une rupture évidente de la transmission intergénérationnelle du corse. Deux émissions de radio font appel à la participation du public. Dans Dite a vostra 1 , les auditeurs ont pour consigne d’user exclusivement du corse : on note la présence récurrente d’emprunts de nécessité mais aussi l’usage généralisé d’incises auxquelles les puristes eux-mêmes n’ont pas conscience d’avoir recours. Dans l’émission Forum , censée se dérouler plutôt en français, on retrouve une présence non négligeable du corse, le plus souvent en situation de contact, semblant ainsi faire écho au comportement des locuteurs dans l’espace public.
Faire équipe entre ciel et terre : le cas des navigants aériens
Authors: Gueudar Delahaye Antonia 
Published: November 2012

Résumé Dans l’aviation civile commerciale, l’équipage s’inscrit dans un temporalité très courte : il se constitue quelques heures avant le départ, ne dure que le temps d’un aller-retour (avec ou sans escales), et change au voyage suivant. Au moment du briefing, les membres de l’équipage découvrent les nouveaux collègues de vol avec lesquels ils vont devoir travailler, composer, coopérer, s’ajuster... Pourtant, à chaque fois, l’équipe nouvellement constituée fonctionne quasiment instantanément. Or, il ne suffit pas de réunir des personnes ensemble pour qu’elles œuvrent collectivement à un même but. Faire équipe suppose de passer de l’agrégat d’individus à un tout. Comment s’opère ce passage ? Centrée sur l’équipe des personnels navigants commerciaux ( pnc ), soit les hôtesses, les stewards et le chef de cabine, notre réflexion tente de dégager les conditions et les processus à l’œuvre dans cette modalité particulière du « faire équipe ».
Refaire parler le métier
Authors: Ravon Bertrand 
Published: November 2012

Résumé À partir de l’expérience d’analyse de la pratique d’une équipe pluridisciplinaire d’un établissement de protection de l’enfance, l’auteur interroge sur un plan pragmatique les processus qui permettent à des professionnels aux métiers très différents de « faire équipe » malgré leurs désaccords et leurs malentendus. La structuration progressive du collectif obéit à une triple dynamique : de réflexivité (à propos de situations éprouvantes), de controverse (relatives aux tensions entre les métiers éducatifs et les métiers domestiques) et d’accordage (propre à ajuster des conceptions du travail discordantes). Prenant appui sur une approche microsociologique de l’activité, le travail collectif d’analyse permet de revaloriser les professions domestiques du travail social à partir de la reconnaissance de leur dimension et de leur portée affectives ; au détriment des professions éducatives et de leur approche plutôt psychologique de la relation d’aide. Plus généralement, l’article suggère que l’équipe est le produit d’une coordination réflexive des multiples savoirs engagés dans le travail éducatif et de soin auprès des personnes vulnérables.
Les médias sont-ils un pouvoir ?
Authors: Kessler David 
Published: November 2012

Résumé La place des médias dans le système politique a sans nul doute contribué ces dernières années à consolider leur dimension de contre-pouvoir et, tous médias confondus, a renforcé leur irruption dans le débat politique : intégrée par les pouvoirs dans la logique de leur action, l’information peut aussi surgir d’elle-même et déranger les architectures préétablies. Mais à l’heure d’Internet et des réseaux sociaux, c’est un cinquième pouvoir qui surgit et menace la prééminence de l’information. Dès lors les médias peuvent se lancer dans une concurrence aussi forte qu’inutile ou au contraire marquer par la rigueur de leur travail leur singularité dans l’espace politique.
Une « révolution » de la prédication catholique en ville ?
Authors: Simiz Stefano 
Published: November 2012

Parce qu’elles sont le lieu d’enjeux confessionnels majeurs au long du XVI e siècle et qu’elles abritent des pouvoirs soucieux de montrer leurs forces et de s’évaluer mutuellement, les villes françaises de la première modernité (1500-1650) ont favorisé le profond renouveau de la prédication chrétienne, particulièrement catholique. En prenant appui sur un héritage médiéval fort, considérablement amplifié par la multiplication des rendez-vous de la chaire (cycles d’avent et de carême, mais aussi nombreuses octaves), on tente alors à la fois d’institutionnaliser et de mieux contrôler les prises de parole, de saturer l’espace et le temps par un flot d’instructions au service de la Réforme catholique. Cela nécessite d’attirer définitivement ou temporairement dans la cité de nouveaux ouvriers apostoliques, souvent disputés à d’autres villes. Le mouvement favorise certes le renforcement des réguliers mendiants, grâce à l’arrivée des congrégations récentes, mais il est marqué aussi par le réveil d’autres acteurs (la parole de l’évêque notamment) et la généralisation des théologaux après 1550. Dans cette évolution où la part des clercs domine, le rôle joué par les municipalités est multiple et décisif (financement de l’œuvre, participation négociée au recrutement des « voix », aide indirecte à la formation des futurs prédicateurs, reconnaissance sociale et civique des orateurs). C’est encore en fondant ou en s’associant à la tenue de sermons au caractère historique, commémoratif et identitaire affirmé que le pouvoir urbain fait la démonstration de sa forte implication dans la défense de la catholicité du territoire et de la société urbains.
Parler de Dieu après une catastrophe
Authors: Lalouette Jacqueline 
Published: November 2012

Le 4 mai 1897, un terrible incendie ravagea le Bazar de la Charité à Paris. Cette catastrophe donna lieu à de nombreuses cérémonies religieuses, essentiellement catholiques. Le 8 mai, un service funèbre fut célébré à Notre-Dame de Paris, en présence du président de la République et de nombreuses personnalités françaises et étrangères. Le prédicateur, le R.P. Ollivier (O.P.) présenta la tragédie comme un châtiment destiné à punir un « siècle orgueilleux » et plus spécialement la France, oublieuse de sa vocation et de ses traditions. Son discours fit scandale et engendra de vives polémiques. D’autres prédicateurs, surtout des dominicains, entretinrent leurs auditeurs de la tragédie du Bazar à l’occasion de services funèbres célébrés à la demande d’une œuvre, par exemple l’Œuvre des Noviciats dominicains ou l’Œuvre Saint-Michel. À l’exception du R.P. Boulanger, ils évitèrent les allusions politiques pour se consacrer à une réflexion religieuse sur le sens de la souffrance et du sacrifice et sur la rédemption de l’humanité, à laquelle les victimes avaient été associées par leur « martyre ». L’image de Dieu qui s’en dégage est celle d’un Dieu terrible, qui est en même temps un Dieu d’amour, puisqu’il ne châtie que pour sauver. En ce mois de Marie, on ne peut que relever le silence presque total fait sur le nom de Marie, lors de ces cérémonies dans lesquelles il était essentiellement question de femmes et de jeunes filles.