bluuebunny/crossref_metadata_2025_split huggingface dataset:
Spanish translation of the Expert Recommendations for Implementing Change (ERIC) compilation
Authors: Van Pelt Amelia E. , Paniagua-Avila Alejandra , Sanchez Amanda , Sila Stephanie , Lowenthal Elizabeth D. , Powell Byron J. , Beidas Rinad S. 
Published: July 2024

Abstract
Background
Most implementation science resources (e.g., taxonomies) are published in English. Linguistic inaccessibility creates a barrier to the conduct of implementation research among non-English-speaking populations, so translation of resources is needed. Translation into Spanish can facilitate widespread reach, given the large proportion of Spanish speakers around the world. This research aimed to systematically translate the Expert Recommendations for Implementation Change (ERIC) compilation into Spanish as an exemplar for the linguistic translation process.

Methods
Using the World Health Organization guidelines, this work translated the ERIC compilation strategy names, short definitions, and thematic clusters through a three-step process: 1) forward translation into Spanish by a native Spanish-speaking implementation scientist, 2) back-translation into English by a bilingual global health researcher, and 3) piloting via virtual focus group discussions with bilingual researchers not conducting implementation research. To achieve a generalizable translation, recruitment targeted a multicultural group of Spanish-speaking researchers. At the conclusion of each step, the transdisciplinary research team (N = 7) met to discuss discrepancies and refine translations. The Spanish version of the ERIC compilation was finalized through group consensus. Reflections from research team meetings and focus group discussions were synthesized qualitatively.

Results
Given that dialectical nuances exist between Spanish-speaking regions, efforts prioritized universally accepted terminology. Team discussions focused on difficult translations, word choice, and clarity of concepts. Seven researchers participated in two focus groups, where discussion surrounded clarity of concepts, alternative word choice for Spanish translations, linguistic formality, grammar, and conciseness. Translation difficulties highlighted lack of precision in implementation science terminology, and the lack of conceptual clarity of words underscored limitations in the application of the compilation.

Conclusions
The work demonstrated the feasibility of translating implementation science resources. As one of the first systematic efforts to translate implementation resources, this study can serve as a model for additional efforts, including translation into other languages and the expansion to conceptual modifications. Further, this work yielded insights into the need to provide conceptual clarity in implementation science terminology. Importantly, the development of Spanish resources will increase access to conduct implementation research among Spanish-speaking populations.
Myoelectrical activity of sternocleidomastoid muscle in smartphone-addicted versus non-addicted individuals
Authors: Elhafez Haytham M. , Mohammed Huda Adel , Ali Ebtesam A 
Published: July 2024

Abstract
Background
Over the past decade, smartphone users have substantially increased, raising concerns about potential musculoskeletal problems associated with long-term use. Prolonged smartphone usage may cause discomfort in the thumb, shoulder, and neck that can be exacerbated over time, thereby affecting the electrical activity of several muscles, such as the sternocleidomastoid muscle (SCM). Accordingly, we aimed to examine the impact of smartphone addiction on the myoelectric activity of the SCM.

Design and method
Forty-four smartphone users, both male and female, aged 18–30 years, were recruited from the Faculty of Physical Therapy, Cairo University, in this observational study. The participants were equally allocated into two groups, A and B, based on their Smartphone Addiction Scale-Short Version (SAS-SV) scores. Group A consisted of smartphone-non-addicted users who scored below 31 for males and 33 for females, whereas group B included smartphone-addicted users who scored over 31 for men and 33 for females. Additionally, the electromyography (EMG) device was used to monitor the electrical activity during rest and maximum voluntary contraction (MVC).

Results
The results showed a significant difference (P < 0.0001) in the electrical activity of the left and right SCMs between the two groups at rest but a nonsignificant difference during MVC.

Conclusion
Smartphone addiction significantly impacts the myoelectric activity of the SCM at rest among young adult smartphone users, but this impact is not significant during MVC.
Carbon footprint in trauma surgery, is there a way to reduce it?
Authors: Lockhorst Elize W. , Schormans Philip M. J. , Berende Cornelis A. S. , van Hensbroek Pieter Boele , Vos Dagmar I. 
Published: July 2024

Abstract
Background
Inhaled anaesthetic agents like sevoflurane contribute for approximately 5% to healthcare’s carbon footprint. Previous studies suggested that the use of these agents should be minimized. Although multiple trauma surgeries can be performed under regional anaesthesia, most are performed under general anaesthesia. This study aims to evaluate the environmental benefits of using regional anaesthesia over general anaesthesia and to compare the associated complication rates.

Methods
This retrospective study included all trauma patients (≥ 18 years) who underwent surgical intervention for hand, wrist, hip, or ankle fractures from 2017 to 2021. The hypothetical environmental gain was calculated based on the assumption that all surgeries were performed under regional anaesthesia. Complication rates were compared between regional and general anaesthesia.

Results
Of the 2,714 surgeries, 15% were hand, 26% wrist, 36% hip, and 23% ankle fractures. General anaesthesia was used in 95%, regional in 5%. Switching this 95% to regional anaesthesia would reduce the sevoflurane use by 92 k, comparable to driving 406,553 km by car. The complication rate was higher with general anaesthesia compared to regional (7.7% vs 6.9%, p = 0.75).

Conclusion
The potential gain of the reduction of sevoflurane in trauma surgeries which can be performed under regional anaesthesia can be significant.
Pleiotropic Effects of an eQTL in the CELSR2/PSRC1/SORT1 Cluster That Associates With LDL-C and Resting Metabolic Rate
Authors: Bandesh Khushdeep , Freeland Kendrick , Traurig Michael , Hanson Robert L , Bogardus Clifton , Piaggi Paolo , Baier Leslie J 
Published: July 2024

Abstract

Context
The locus CELSR2-PSRC1-SORT1, a primary genetic signal for lipids, has recently been implicated in different metabolic processes. Our investigation identified its association with energy metabolism.

Objective
This work aimed to determine biological mechanisms that govern diverse functions of this locus.

Methods
Genotypes for 491 265 variants in 7000 clinically characterized American Indians were previously determined using a custom-designed array specific for this longitudinally studied American Indian population. Among the genotyped individuals, 5205 had measures of fasting lipid levels and 509 had measures of resting metabolic rate (RMR) and substrate oxidation rate assessed through indirect calorimetry. A genome-wide association study (GWAS) for low-density lipoprotein cholesterol (LDL-C) levels identified a variant in CELSR2, and the molecular effect of this variant on gene expression was assessed in skeletal muscle biopsies from 207 participants, followed by functional validation in mouse myoblasts using a luciferase assay.

Results
A GWAS in American Indians identified rs12740374 in CELSR2 as the top signal for LDL-C levels (P = 1 × 10−22); further analysis of this variant identified an unexpected correlation with reduced RMR (effect = −44.3 kcal/day/minor-allele) and carbohydrate oxidation rate (effect = −5.21 mg/hour/kg-EMBS). Tagged variants showed a distinct linkage disequilibrium architecture in American Indians, highlighting a potential functional variant, rs6670347 (minor-allele frequency = 0.20). Positioned in the glucocorticoid receptor's core binding motif, rs6670347 is part of a skeletal muscle-specific enhancer. Human skeletal muscle transcriptome analysis showed CELSR2 as the most differentially expressed gene (P = 1.9 × 10−7), with the RMR-lowering minor allele elevating gene expression. Experiments in mouse myoblasts confirmed enhancer-based regulation of CELSR2 expression, dependent on glucocorticoids. Rs6670347 was also associated with increased oxidative phosphorylation gene expression; CELSR2, as a regulator of these genes, suggests a potential influence on energy metabolism through muscle oxidative capacity.

Conclusion
Variants in the CELSR2/PSRC1/SORT1 locus exhibit tissue-specific effects on metabolic traits, with an independent role in muscle metabolism through glucocorticoid signaling.
Negotiating Work and Family Spheres: The Dyadic Effects of Flexible Work Arrangements on Fertility Among Dual-Earner Heterosexual Couples
Authors: Wang Senhu , Tan Jolene 
Published: July 2024

Abstract
Academics and policymakers have suggested making flexible work arrangements (FWAs) the default in workplaces to promote a family-friendly workplace culture conducive to having and raising children. However, systematic research investigating how FWAs, as a long-term approach to negotiating work–family spheres, are related to fertility among dual-earner heterosexual couples is limited. Drawing on the linked-lives perspective, we theorize the relationship between FWAs and fertility among couples and potential variation depending on the interplay of both spouses’ work and family characteristics. We test our hypotheses using longitudinal couple-level dyadic data in the United Kingdom (2010–2022). We find that although FWA availability alone is unrelated to fertility, wives’ (not husbands’) FWA use is significantly associated with a higher probability of experiencing a first birth. Moreover, the effect of wives’ FWA use is particularly pronounced when both spouses work in professional and managerial occupations and when husbands contribute a larger proportion of income and at least equal housework. This study reveals a gendered effect of FWAs on fertility across work–family arrangements, deepening our understanding of couple-level dynamics in the fertility process.
Information Ambiguity, Market Institutions, and Asset Prices: Experimental Evidence
Authors: Bao Te , Duffy John , Zhu Jiahua 
Published: July 2024

We explore how information ambiguity and traders’ attitudes toward such ambiguity affect expectations and asset prices under three different market institutions. Specifically, we test a theoretical prediction that information ambiguity will lead market prices to overreact to bad news and underreact to good news. We find that such an asymmetric reaction exists and is strongest in individual prediction markets. It occurs to a lesser extent in single price call markets. It is weakest of all in double auction markets, in which buyers’ asymmetric reaction to good/bad news is cancelled out by the opposite asymmetric reaction of sellers. This paper was accepted by Camelia Kuhnen, finance. Funding: Financial support from a Tier 1 Grant from MOE of Singapore [Grant RG 69/19], NTU-WeBank JRC [Grant NWJ-2020-003], the National Natural Science Foundation of China [Grants 72303170, 72141304], and the National Key Research and Development Program of China [Grant 2022YFC3303304] is gratefully acknowledged. Supplemental Material: The online appendix and data files are available at https://doi.org/10.1287/mnsc.2022.01223 .
Physician Adoption of AI Assistant
Authors: Hou Ting , Li Meng , Tan Yinliang (Ricky) , Zhao Huazhong 
Published: July 2024

Problem definition: Artificial intelligence (AI) assistants—software agents that can perform tasks or services for individuals—are among the most promising AI applications. However, little is known about the adoption of AI assistants by service providers (i.e., physicians) in a real-world healthcare setting. In this paper, we investigate the impact of the AI smartness (i.e., whether the AI assistant is powered by machine learning intelligence) and the impact of AI transparency (i.e., whether physicians are informed of the AI assistant). Methodology/results: We collaborate with a leading healthcare platform to run a field experiment in which we compare physicians’ adoption behavior, that is, adoption rate and adoption timing, of smart and automated AI assistants under transparent and non-transparent conditions. We find that the smartness can increase the adoption rate and shorten the adoption timing, whereas the transparency can only shorten the adoption timing. Moreover, the impact of AI transparency on the adoption rate is contingent on the smartness level of the AI assistant: the transparency increases the adoption rate only when the AI assistant is not equipped with smart algorithms and fails to do so when the AI assistant is smart. Managerial implications: Our study can guide platforms in designing their AI strategies. Platforms should improve the smartness of AI assistants. If such an improvement is too costly, the platform should transparentize the AI assistant, especially when it is not smart. Funding: This research was supported by a Behavioral Research Assistance Grant from the C. T. Bauer College of Business, University of Houston. H. Zhao acknowledges support from Hong Kong General Research Fund [9043593]. Y. (R.) Tan acknowledges generous support from CEIBS Research [Grant AG24QCS]. Supplemental Material: The online appendix is available at https://doi.org/10.1287/msom.2023.0093 .
Design and analysis of an ultra-wide-angle laser communication optical system
Authors: Hu Lichao , An Yan , Li Zexiang , Li Jianhong , Song Yansong , Dong Keyan 
Published: July 2024

With the development of information networks and laser communication technology, the coverage communication form of inter-satellite networks has become crucial. In order to solve the problems of a small communication field of view and difficult integration, an optical system design method for network laser communication is proposed. Based on the ultra-wide-angle system, the non-similar imaging principle is used to realize the design of a large field of view omnidirectional optical antenna, and the communication link of the antenna is analyzed accordingly. The results show that the communication field of view of the antenna can reach 130°, and the beam divergence angle increases from 420 to 2000 µrad in this range, which can realize long-distance laser communication with a communication rate of 5 Gbps. The design method proposed in this paper provides a new design idea for the development of a laser communication optical antenna, which has great application potential in the field of inter-satellite laser communication networking.
Stray light analysis and suppression of a UV multiple sub-pupil ultra-spectral imager
Authors: Zhang Xv , Li Bo , Zhi Dan Dan , Fang Xin , Li Tao , Du Wei Feng , Wang Xiao Xv , Li Han Shuang , Sun Fu Kun , Gu Guo Chao 
Published: July 2024

A multiple sub-pupil ultra-spectral imager system for simultaneous
detection of multiple substances is proposed. By employing pupil
separation prisms and grating multilevel spectra, the system achieves
simultaneous detection of three spectral channels with a single
spectrometer and detector, featuring an ultra-high spectral resolution
of 0.1 nm. However, due to simultaneous detection of three
channels, the system suffers from significant stray light issues. In
response to this problem, a UV multiple sub-pupil ultra-spectral
imager system optical-machinery model is constructed in this article.
The main sources of stray light are determined through theoretical
derivation and simulation analysis, and the level of stray light in
the system is analyzed using simulation analysis software. A structure
for stray light suppression is optimized, and the use of multispectral
filters is proposed to suppress stray light generated by spectral
crosstalk in the system. The effectiveness of stray light suppression
is evaluated based on the energy response of the receiving surface.
The analysis results show that after optimization, the level of stray
light in the T1 channel is reduced from 1.4% to
0.65‰, in the T2 channel from 3.0‰ to 0.5‰, and in the T3 channel from 0.16‰ to 0.05‰.
Therefore, it can be concluded that the proposed method for stray
light suppression in the UV multiple sub-pupil ultra-spectral imager
system addressed in this article meets the indicator requirements.
Improving prevention and early detection of sepsis among patient groups at risk: Introducing a model for a multimodal information campaign—The SepWiss study protocol
Authors: Abels Wiltrud , Reinhart Konrad , Neugebauer Edmund , Wulkotte Elisa , Toubekis Evjenia , Piedmont Silke , Born Sebastian , Rieck Thorsten , Wegwarth Odette , Spies Claudia , Schlattmann Peter , Schwarzkopf Daniel , Fleischmann-Struzek Carolin 
Published: July 2024

Background
Sepsis is a life-threatening organ dysfunction due to a dysregulated host response to infection. Annually, sepsis leads to approx. 90.000 deaths in Germany. Risk factors include amongst others older age (>60), innate or acquired dysfunction of the immune system, and underlying chronic diseases of the lung, heart, liver, or kidneys. The manifestation of sepsis is a medical emergency, and patient outcomes depend on timely diagnosis and immediate treatment. In addition, vaccinations e.g., against pneumococci or influenza virus, are a highly effective public health tool to prevent the most common underlying infections that may lead to sepsis. However, a lack of public awareness for the relevance of vaccination and detecting sepsis as an emergency underlines the need for public health interventions that address these issues. SepWiss aims to evaluate the effects of a multimodal information campaign designed to address this lack of awareness among the risk population in Germany.

Methods
SepWiss is an intervention at state level, consisting of a multimodal information campaign targeting risk groups in the German federal states of Berlin and Brandenburg (intervention region). Based on available evidence, various information formats were developed and implemented by outdoor advertising, social media, educational formats and through stakeholders’ platforms, starting in August 2021. The control region comprises of the remaining 14 German federal states. We will analyze vaccination coverage (primary outcome), and sepsis knowledge, the ability to detect sepsis as an emergency, and attitude towards vaccination (secondary outcomes) amongst the risk population in a controlled before-after comparison. The implementation is accompanied by a mixed-method process evaluation.

Discussion
SepWiss is the first project of its kind to evaluate a complex multi-faceted evidence-based information campaign with regards to the topics of vaccination coverage, and the importance of sepsis detection and prevention for the most vulnerable populations in Germany. Results will be valuable for informing further nationwide campaigns.

Trial registration
German Registry for Clinical Trials: DRKS00024475. Registered February 24th, 2021.
A Rare Presentation of Indirect Hyperbilirubinemia: Coexistence of Multiple UGT1A1 Gene Variants
Authors: Tran Phi , Grimbergen Andrea , Lewis Megan , Yi Ruiyang , Williams Christopher 
Published: July 2024

ABSTRACT
Indirect hyperbilirubinemia is a common clinical finding and rarely can be attributed to Crigler-Najjar syndrome type 2 or Gilbert syndrome. This case displays a rare presentation of indirect hyperbilirubinemia in a patient with multiple UGT1A1 gene variants. We aim to discuss the complexity of multiple UGT1A1 gene variants and its effect on the degree of observed hyperbilirubinemia.
Comparative assessment for nutritional and antinutritional qualities revealed better performance of traditional white-fleshed sweet potatoes than orange-fleshed sweet potatoes
Authors: OGAH Onwuchekwa , ENE Chikezie Onuora , EBENYI Lilian Nwanneka , FREDERICK Orinya Onyebuchi , OKPURU Ifeanyi Godwin , NWANKWO Stephen Elem 
Published: July 2024

Recent introduction of beta-carotene rich orange-fleshed sweet potatoes (OFSP) has resulted to consumers’ low demands for traditional white-fleshed sweet potatoes (TWFSP), without due consideration of their nutritional qualities. This study appraised the nutritional compositions of OFSP and TWFSP. They were analyzed for mineral content, antinutrients, and phytochemicals at National Root Crops Research Institute, Umudike. The field experiment was conducted using randomized complete block design with three replicates. TWFSP showed higher concentrations of minerals, anti-nutrients and phytochemicals than OFSP. In TWFSP, potassium ranged from 1879.20 ± 0.01 mg kg-1 (‘B3V3’) to 1960.30 ± 0.01 mg kg-1 (‘B2V2’) while in OFSP it varied from 1162.60 ± 0.02 mg kg-1 (‘B26T26’) to 1800.20 ± 0.01 mg kg-1 (‘B10T10’). The antinutrients and phytochemicals results showed that flavonoids in TWFSP ranged from 0.30 ± 0.01 mg TAE kg-1 (‘B1V1’) to 970.50 ± 0.02 mg TAE kg-1 (B3V3) while it varied from 0.20 ± 0.01 mg TAE kg-1 (‘B4T4’) to 670.30 ± 0.01 mg TAE kg-1 (‘B8T8’) in OFSP. Heritability estimates were high for all antinutrients and minerals while genetic advance was high only for potassium (42.206) and phosphorus (10.288) traits. Variation between phenotypic coefficient of variation and genotypic coefficient of variation was negligible, with the former higher for most minerals and antinutrients. TWFSP were found richer than OFSP, and suggests improvement by selection.
Development and validation of Adolescent Sexual and Reproductive Health – Knowledge, Attitude, and Self-Efficacy Questionnaires (ASRH-KASeQ)
Authors: Setiyorini Ana , Sitaresmi Mei N. , Nisman Wenny A. 
Published: July 2024

Abstract

Objectives
The tools to measure knowledge, attitudes, and self-efficacy related to adolescent sexual and reproductive health have been developed, but with adolescent subjects over 15 years old and with specific topics. The needs and focus of SRH education in adolescents are different from those of young adults. This study aimed to develop a valid and reliable tool to measure adolescents’ knowledge, attitude, and self-efficacy regarding SRH.

Methods
A total of 100 items were developed based on a literature search, focus group discussion, and expert panel encompassing three domains: knowledge, attitude, and self-efficacy. The Adolescent Sexual and Reproductive Health – Knowledge, Attitude, and Self-Efficacy Questionnaires (ASRH-KASeQ) then underwent a validation process that included content validity, face validity, and internal consistency reliability. This study was conducted on adolescents aged 12–15 years in secondary school in Yogyakarta, Indonesia. All statistical methods were analyzed using STATA software.

Results
The average content validity (S-CVI/Ave) and face validity (S-FVI/Ave) for knowledge, attitude, and self-efficacy demonstrated good validity with scores of 0.93 and 0.94, 0.92 and 0.96, and 0.95 and 0.96, respectively. The internal consistency reliability using Cronbach’s alpha for the knowledge, attitude, and self-efficacy domains exceeded 0.6, with results of 0.7, 0.81, and 0.89, which were considered acceptable.

Conclusions
The final set of ASRH-KASeQ consisted of 100 items measuring knowledge (40 items), attitude (30 items), and self-efficacy (30 items) of adolescents SRH. ASRH-KASeQ was shown to be a reliable and valid tool for Indonesian adolescents, especially those aged 12–15 years.