bluuebunny/crossref_metadata_2025_split huggingface dataset:
Quantitative and qualitative evaluation of maltodextrin products in the industry using near‐infrared spectroscopy
Authors: Sringarm Chayanid , Numthuam Sonthaya , Jiamyangyuen Sudarat , Kittiwachana Sila , Kielar Filip , Wongsaipun Sakunna , Rungchang Saowaluk 
Published: August 2024

SummaryMaltodextrin is a crucial ingredient in food and pharmaceutical sectors. Traditional quality assessment methods for maltodextrin are destructive and time consuming. This study aimed to employ near‐infrared (NIR) spectroscopy and chemometrics to differentiate maltodextrin variants and measure their quality parameters efficiently. NIR spectra were recorded in the range of 12 000–4000 cm−1 using the transflectance mode. The classification model effectively distinguished maltodextrin types based on their dextrose equivalent (DE) values using techniques such as partial least squares‐discriminant analysis and supervised self‐organising map (SSOM). Moreover, quality parameters including moisture content, DE value, maltose, maltotriose, pH, and SO2 were quantitatively assessed using partial least squares regression (PLSR) and SSOM models. Particularly, PLSR provided better results, with residual predictive deviation values exceeding 2.5 for moisture content, DE values, maltose, and maltotriose. These models can be applied for use in both laboratory settings and industrial monitoring.
New ophthalmic lasers for the evaluation and treatment of retinal disease
Authors: Freeman William R , Bartsch Dirk‐Uwe 
Published: August 2024

AbstractOphthalmic lasers are used as diagnostic as well as therapeutic modalities in patients with retinal diseases. Recent advances in laser technology have allowed more convenient selection of wavelength and a wide variety of delivery systems is available to deliver the laser energy to the retina. In addition, newer lasers that disrupt and cut tissue will become available for use in patients with retinal diseases. The use of imaging lasers and lasers in combination with dyes selectively to enhance their effects have become useful in diagnosis and understanding of pathophysiology of diseases. These lasers will also be therapeutically useful. This manuscript delineates the new types of diagnostic and therapeutic lasers, new imaging dyes and techniques as they apply to retinal diseases as well as the principles of laser‐tissue interaction as applied to the retina. This should allow the ophthalmologist who treats patients with retinal diseases to make more intelligent decisions regarding the use and acquisition of laser systems.
Paraquat causes chronic ocular surface toxicity
Authors: Vlahos Kerry , Goggin Michael , Coster Douglas 
Published: August 2024

AbstractWe describe a case of topical exposure to a commercial solution of paraquat. Chronic, severe ocular surface destruction resulted, probably due to absorption of the herbicide into the surface tissues, facilitated by a surfactant present in the preparation, and to intracellular redox cycling of the paraquat cation. Ocular paraquat toxicity is described and explained in the context of the toxicity of systemic absorption.
Increased mRNA expression for serotonin receptor 1B (HTR1B) is associated with thrombosis in BCR::ABL1‐negative myeloproliferative neoplasms
Authors: Gurban Petruta , Mambet Cristina , Botezatu Anca , Necula Laura G. , Matei Lilia , Neagu Ana Iulia , Pitica Ioana Madalina , Dragu Laura Denisa , Nastasie Schulman Alina , Ataman Marius , Nedeianu Saviana , Chivu‐Economescu Mihaela , Bleotu Coralia , Anton Gabriela , Diaconu Carmen Cristina 
Published: August 2024

AbstractBCR::ABL1‐negative myeloproliferative neoplasms (MPNs) are clonal haematopoietic stem cell disorders characterized by specific driver mutations and an increased risk of both macrothrombosis and microthrombosis. Serotonin receptor type 1B (HTR1B) was found to be expressed by various solid tumours, and also primary bone marrow mononuclear cells from myelodysplastic neoplasm and acute myeloid leukaemia patients, representing a potential therapeutic target. In this study we assessed for the first time the expression levels of HTR1B mRNA in the peripheral blood mononuclear cells (PBMC) of 85 newly diagnosed MPN patients, consisting of 28 polycythemia vera, 25 essential thrombocythemia and 32 primary myelofibrosis cases. Levels of HTR1B expression between MPN subtypes and control group were not significantly different. However, at clinical data examination, it was observed that MPN patients with a recent history of major thrombosis and/or signs of impaired microcirculation exhibited significantly higher HTR1B expression levels compared to non‐thrombotic MPNs and control group. Moreover, thrombotic MPN patients had significantly higher HTR1B expression than patients with recent thrombosis and absence of MPN diagnostic criteria. These findings suggest that increased levels of HTR1B expression in PBMC might be associated with thrombosis in MPN patients, but larger studies are needed for confirmation, including testing of the receptor protein expression level.
Recognising floods, recognising people? Flood risk management in riverfront urban kampongs of Indonesia
Authors: Wiering Mark , MacAfee Elizabeth , Saharan Tara , Damm Muhammad , Irvan Muhammad , Priadi Cindy Rianti , Kaufmann Maria , Rakhmani Inaya , de Jong Edwin 
Published: August 2024

AbstractFlood risks can stem from various causes and exhibit distinct characteristics that shape the way they are governed. Depending on flood risk characteristics, specific policies are designed and organisations are involved. In Indonesia, like in other regions, organisational divisions are made for coastal floods, fluvial floods and pluvial floods (resulting from tides, rivers and rain, respectively). The Indonesian cities of Manado and Pontianak both face recurring floods. However, the characteristics of and responses to these floods are different, with consequences for distributive, procedural as well as recognition justice in those cities. In line with Fraser, we define recognition justice in relation to three forms of misrecognition: cultural domination, disrespect, and non‐recognition, with examples from Manado and Pontianak. We show that the misrecognition of certain types of floods overlaps and interacts with the non‐recognition of low‐income informal settlements, disrespect and stereotyping of residents of these areas, and a lack of attentiveness to the culture, livelihoods and practices of people who live alongside rivers. In this way, we examine the landscape of recognition justice in the event of flooding in an urban context, drawing on qualitative interview data gathered from the cities of Manado and Pontianak. The following questions are considered: Who experiences misrecognition? By whom is this misrecognition perpetrated? At which level (institutional frameworks or laws, implementation or social practices) and what are the resulting consequences of this misrecognition? Finally, we explore the interactions between different forms of misrecognition, which create a foundation for further distributional and procedural injustices.
Function of a complex of p‐Y42 RhoA GTPase and pyruvate kinase M2 in EGF signaling pathway in glioma cells
Authors: Lee Yoon‐Beom , Park Yohan , Hamza Amir , Min Jung Ki , Dogsom Oyungerel , Kim Sung‐Chan , Park Jae‐Bong 
Published: August 2024

AbstractEpidermal growth factor (EGF) is known to be a critical stimulant for inducing the proliferation of glioma cancer cells. In our study, we observed that GST‐RhoA binds to pyruvate kinase M2 (PKM2) in vitro. While EGF reduced the levels of RhoA protein, it significantly increased p‐Y42 RhoA, as well as PKM1 and PKM2 in LN18 glioma cell line. We determined that RhoA undergoes degradation through ubiquitination involving SCF1 and Smurf1. Interestingly, we observed that p‐Y42 RhoA binds to PKM2, while the dephosphomimetic form, RhoA Y42F, did not. Additionally, our observation revealed that PKM2 stabilized both RhoA and p‐Y42 RhoA. Importantly, RhoA, p‐Y42 RhoA, and PKM2, but not RhoA‐GTP, were localized in the nucleus upon EGF stimulation. Knockdown of RhoA with siRNA resulted in the reduced levels of phosphoglycerate kinase1 (PGK1) and microtubule affinity‐regulating kinase 4 (MARK). Furthermore, we found that the promoter of PGK1 was associated with β‐catenin and YAP. Notably, p‐Y42 RhoA and PKM2 co‐immunoprecipitated with β‐catenin and YAP. Based on these findings, we proposed a novel mechanism by which p‐Y42 RhoA and PKM2, in conjunction with β‐catenin and YAP, regulate PGK1 expression, contributing to the progression of glioma upon EGF.
image
‘From the Ivory Tower’? Memory Workers and Mnemonic Practices in Communities
Authors: Sadeghi Yasaman 
Published: August 2024

AbstractMemory work involves mnemonic practices such as remembering, forgetting, and enactment of the past to address past wrongdoing, foster future action, and contribute to a sense of belonging. Working with diversity and plurality of memories, however, necessitates confronting the underlying politico‐ethical considerations and struggles when memory work transcends organizational bounds. This study focuses on the viewpoints of memory workers in communities in order to theorize the various possibilities and limitations of memory work as such. In this work, the politico‐ethical tensions are evident between the requirements of practicing an occupation and those of the communities, who in turn exhibit hierarchies, conflicts, and diversity within and between themselves. I suggest that taking a community‐centric approach to memory work can serve the dynamic integrity of memories, and foster community engagement and empowerment. Memory workers, then, can account for the politico‐ethical struggles over memories by orchestrating interpretive, open, and embodied mnemonic practices to remain in tune with the diverse, disputed, polyvocal, and ever‐unfolding memories. The contributions of this paper carry implications for a more pluralistic and dynamic approach to memory work, suited to our times marked by increased historical consciousness, rival memories, and fierce debates over what and how must be remembered.
Mixed‐Effects Modeling with a Multinomial Dependent Variable
Authors: Gudmestad Aarnes , Metzger Thomas A. 
Published: August 2024

AbstractIn this Methods Showcase Article, we illustrate mixed‐effects modeling with a multinomial dependent variable as a means of explaining complexities in language. We model data on future‐time reference in second language Spanish, which consists of a nominal dependent variable that has three levels, measured over 73 participants. We offer step‐by‐step procedures for multinomial logistic regression with fixed and random effects, and we discuss the interpretation of the model and its advantages and limitations.
Does aid for trade promote FDI from enterprises of donors to recipient countries? Based on the spatial spillover effect of China's Aid for Trade
Authors: Sun Churen , Zhao Jiamin , Xu Jinqiang , Liang Jingjing 
Published: August 2024

AbstractThis paper investigates the direct and spatial spillover effects of China's Aid for Trade (AfT) on Chinese enterprises' foreign direct investment (FDI) in recipient countries. The results show that China's AfT can effectively promote FDI by Chinese firms in recipient countries, and the promotion effect is determined by both the direct effect and the spatial spillover effect. The mechanism test finds that China's AfT can promote FDI by Chinese firms through improving the infrastructure of the recipient countries and enhancing the image of the residents of the recipient countries toward China. The study suggests that the introduction of spatial spillover effects in the study of aid is of great significance in promoting the development of research in the field of aid. This paper enriches the conclusions of aid research in the field of economics on the one hand and broadens the boundaries of aid effectiveness research on the other hand.
Subsidizing a sports arena in a bankrupt city: Detroit's Little Caesars Arena
Authors: Sroka Robert 
Published: August 2024

AbstractObjectivesThe potential for ancillary real estate transformation and downtown revitalization has moved to the forefront of sports venue subsidy arguments. Despite the City of Detroit being in the largest municipal bankruptcy in U.S. history at the time, $324 million in public funding was directly provided to Little Caesars Arena, a new home for the Detroit Red Wings hockey team. Using the Detroit context, this article examines how a major arena subsidy deal arose in a severely financially distressed city.MethodsUsing a snowball technique, documents were collected from government, media, industry, community, legal, and academic sources to inform a retrospective, single case study. Over 300 documents covering a period from 1992 to 2021 were then reviewed for prospective relevance. A review of secondary media sources was conducted in lieu of traditional interviews.ResultsThe arena funding outcome is best explained by three interrelated aspects: local growth coalitions, real estate development promises, and lacking procedural and financial transparency exacerbated by both the chosen funding mechanism of tax increment financing (TIF) and the bankruptcy.ConclusionsWhere flexible financial subsidies and arena deal making are concerned, procedural transparency matters. Growth coalitions and rent‐seeking team owners can use the earmarked nature of TIF to circumvent traditional budgetary processes and mute prospective opposition through promises of self‐financing subsidies that will not result in new tax rate hikes. For venue deals where the substance is in the details of contractual obligations, transparency and adequate time for scrutiny are especially important.
Clinical outcomes of lung transplant recipients with pre‐transplant Mycobacterium avium complex infection
Authors: Kothadia Sonya M. , Cober Eric E. , Koval Christine E. , Golbin Jem M. , Harrington Susan , Miranda Cyndee , Benninger Lauryn A. , Banzon Jona M. 
Published: August 2024

AbstractBackgroundLung transplant recipients (LTRs) are at risk for Mycobacterium avium complex (MAC) infections, in part due to the presence of structural lung disease pre‐transplant and relatively higher levels of immunosuppression post‐transplant. There is a lack of data regarding outcomes of LTR with MAC infections pre‐transplant.MethodsThis is a single‐center retrospective analysis of patients who received lung transplants (LTs) from 2013 to 2020 with 1) evidence of MAC on culture or polymerase chain reaction before or at the time of transplant or 2) granulomas on explant pathology and positive acid‐fast bacillus stains with no other mycobacteria identified. Patients were deemed to have MAC pulmonary disease (MAC‐PD) if they met the American Thoracic Society/Infectious Disease Society of America criteria.ResultsFourteen patients (14/882, 2%) met inclusion criteria. Seven patients (7/14, 50%) had pre‐transplant MAC‐PD, four of whom had cavitary disease. None of the 14 patients had smear‐positive cultures at the time of transplant. Two patients in our cohort received treatment for MAC before transplant. Thirteen patients were bilateral LTR (13/14, 93%). One single LTR was the sole patient to receive MAC treatment post‐transplant. No patients developed MAC‐PD after transplant.ConclusionThe bilateral LTR in our cohort did not develop MAC‐PD despite not receiving MAC treatment post‐transplant. It is possible source control was achieved with native lung explantation. Our observations suggest patients may not uniformly require pre‐ or post‐transplant MAC treatment if they are smear‐negative and undergo bilateral LT.
image
Incidence of opportunistic viral infections in hepatitis C virus nucleic acid test negative recipients of kidneys from hepatitis C virus nucleic acid test positive donors
Authors: Shah Krishna , Katz‐Greenberg Goni , Steinbrink Julie , Crona Lana , Erkanli Alaattin , Lee Hui‐Jie , Yang Chengxin , Byrns Jennifer 
Published: August 2024

AbstractBackgroundIn kidney transplantation, concerns have been raised regarding increased incidence of viral opportunistic infections in hepatitis C virus (HCV) nucleic acid test (NAT)‐negative (‐) recipients who received HCV NAT‐positive (+) donor kidneys, specifically BK polyomavirus (BKPyV), cytomegalovirus (CMV), and Epstein‐Barr virus (EBV). The purpose of this study was to determine the incidence of these three viral opportunistic infections in HCV NAT‐ recipients who have undergone kidney transplantation with HCV NAT+ donor kidneys at our institution.MethodsThis was an Institutional Review Board‐approved, single‐center, retrospective case‐control study of HCV NAT‐ kidney transplant recipients with HCV NAT+ donors from 2018 to 2021. The primary outcome was the cumulative incidence of viral infections of BKPyV, CMV, and/or EBV within 1 year following kidney transplantation.ResultsA total of 231 patients were included, 77 in the exposed (donor HCV NAT+) group and 154 in the control (donor HCV NAT‐) group. The adjusted cumulative incidence of viremia within 1 year did not statistically differ between groups (77% exposed group versus 66% for the control group, hazard ratio 1.34, 95% confidence interval 0.95–1.89). In addition, no statistically significant differences were observed for secondary outcomes with the exception of CMV viremia (62% exposed versus 49% control, p = 0.021). However, there were more patients in the exposed group at high risk for CMV viremia based on serostatus (CMV Donor+/Recipient‐, D+/R‐).ConclusionAmong patients who received HCV NAT+ donor kidneys, no clear association was observed between exposure to HCV NAT+ donor kidneys and viral infections of BKPyV, CMV, or EBV.
image
Application of Laminate Theory to Plate Elements Based on Absolute Nodal Coordinate Formulation
Authors: Zhang Zhaowei , Gerstmayr Johannes , Zhang Wei 
Published: August 2024

Abstract
Laminated plates have a wide range of applications in engineering, and their flexibility becomes increasingly significant with the development of lightweighting technology. The absolute nodal coordinate formulation (ANCF) has emerged as a promising approach for modeling flexible multibody dynamics. However, researches on thick laminated plates with shear deformation for multiflexible systems remain limited. To investigate the application of ANCF plate elements for laminated plates, this article introduces a new laminated plate element that considers shear deformation. We utilize the fully parameterized ANCF plate element to analyze laminated composite structures, focusing specifically on their layers in the thickness direction. By employing a structural mechanics approach, the study achieves a uniform stiffness matrix that can adapt to laminated plates with shear deformation and can be precomputed in advance. Additionally, a summary of a thin laminated plate element is provided for comparison. Both plate elements are composed by layers, and their elastic forces and Jacobian matrices are derived using first-order shear theory and Kirchhoff's theory, respectively. The effectiveness and accuracy of the proposed elements are validated through a series of benchmark problems encompassing modal, static, and dynamic investigations. The study thoroughly analyzes the results compared with the commercial finite element method software abaqus and analytical approach. The findings demonstrate that the methods effectively address laminated plates.
Pressure Gain Combustion for Gas Turbines: Analysis of a Fully Coupled Engine Model
Authors: Klein Rupert , Nadolski Maikel , Zenker Christian , Oevermann Michael , Paschereit Christian Oliver 
Published: August 2024

Abstract
The “Shockless Explosion Combustion” (SEC) concept for gas turbine combustors, introduced in 2014, approximates constant volume combustion (CVC) by harnessing acoustic confinement of auto-igniting gas packets. The resulting pressure waves simultaneously transmit combustion energy to a turbine plenum and facilitate the combustor's recharging against an average pressure gain. Challenges in actualizing an SEC-driven gas turbine include (i) the creation of charge stratifications for nearly homogeneous auto-ignition, (ii) protecting the turbocomponents from combustion-induced pressure fluctuations, (iii) providing evidence that efficiency gains comparable to those of CVC over deflagrative combustion can be realized, and (iv) designing an effective one-way intake valve. This work addresses challenges (i)–(iii) utilizing computational engine models incorporating a quasi-one-dimensional combustor, zero- and two-dimensional (2D) compressor and turbine plena, and quasi-stationary turbocomponents. Two SEC operational modes are identified which fire at roughly one and two times the combustors' acoustic frequencies. Results for SEC-driven gas turbines with compressor pressure ratios of 6:1 and 20:1 reveal 1.5-fold mean pressure gains across the combustors. Assuming ideally efficient compressors and turbines, efficiency gains over engines with deflagration-based combustors of 30% and 18% are realized, respectively. With absolute values of 52% and 66%, the obtained efficiencies are close to the theoretical Humphrey cycle efficiencies of 54% and 65% for the mentioned precompression ratios. Detailed thermodynamic cycle analyses for individual gas parcels suggest that there is room for further efficiency gains through optimized plenum and combustor designs.
Speed Strategy on High-Pressure Compressor for the Charging Process of Advanced Adiabatic Compressed Air Energy Storage During Dynamic Shutdown
Authors: Wang Yi , Qin Guoliang , Jia Cheng , Cui Qin 
Published: August 2024

Abstract
Advanced adiabatic compressed air energy storage (AA-CAES) starts and shuts down frequently. The default operation of the high-pressure compressor (HP) connected to the cavern is to reduce the speed of the inverter motor during shutdown. Whether or not the default speed strategy is safe has yet to be focused on. To this end, a detailed charging process comprising three series of centrifugal compressors with intercoolers was constructed within the framework of unisimdesign. The safety measures were meticulously considered by integrating antisurge circuits, vent valves, and check valves. Proportional–integral (PI) controllers were allocated to the primary component to govern the shutdown procedure. The speed strategy of the HP inverter motor during the load shedding stage is the focus of research. Six speed strategies, including decreasing speed, constant speed, and increasing speed, were discussed, respectively. The discussion focused on changes made to air injection, inlet mass flow of the HP, inlet and outlet pressure of both the middle-pressure compressor (MP) and HP, and energy efficiency. The study found that implementing the minimum allowable speed for the inverter motor speed (IMS) and increasing speed during the load shedding stage can cause fluctuations in the air injection. As IMS increases at the end of the load shedding stage, the pressure anomalies at the MP outlet and the HP inlet weaken, and the shutdown process's energy efficiency improves. The HP inlet flow fluctuations caused by various strategies were within an acceptable range. This study reveals that there is a mutual influence between components in the charging process of AA-CAES. An appropriate speed strategy for the HP inverter motor can mitigate the operational hazards. The results of this study can provide guidance for similar AA-CAES shutdowns.