bluuebunny/crossref_metadata_2025_split huggingface dataset:
The importance of IL-6 protein expression in primary human renal cell carcinoma: an immunohistochemical study: Figure 1
Authors: Paule Bernard , Belot Jacqueline , Rudant Christiane , Coulombel Colette , Abbou Claude Clément 
Published: July 2002

Aims—Interleukin 6 (IL-6) is produced by some renal carcinoma cell lines in vitro. This might be biologically important because IL-6 is a cytokine of particular interest, owing to its involvement in the growth of renal cell carcinoma. In this study, the expression of IL-6 protein in tissue samples from primary renal cell carcinoma was analysed, and then its clinical importance was examined.Methods—The distribution of IL-6 in renal cell carcinoma was examined by means of an immunohistochemical method in 47 untreated primary renal cell carcinoma samples. The search for a significant difference between histological patterns, Furhman's grading system, TNM classification, and IL-6 protein expression was carried out.Results—Immunohistochemistry demonstrated that IL-6 is expressed in 70% of primary tumours. There was no significant difference in the tumour size and grade between renal cell carcinomas with or without IL-6 expression. However, a relatively large number of high grade tumours expressed IL-6.Conclusion—The importance of IL-6 expression with regard to tumour size/local growth is questionable because IL-6 has been correlated with the development of metastatic disease. These data suggest that the production of IL-6 could exert a growth inhibitory effect on primary renal cell carcinoma.
Influence of solvent exposure and aging on cognitive functioning: an 18 year follow up of formerly exposed floor layers and their controls
Authors: Nilson L Nordling , Sällsten G , Hagberg S , Bäckman L , Barregård L 
Published: July 2002

Objectives: To extend our knowledge of how exposure to neurotoxic substances during working life affects cognitive functioning in the long term. Does long term occupational exposure to organic solvents lead to aggravated cognitive impairment later in life?Methods: A follow up was conducted of floor layers exposed to solvents and their unexposed referents (carpenters) 18 years after the baseline assessment. The pattern of cognitive changes in the two groups was compared, with the same 10 neuropsychological tests from the test battery for investigating functional disorders (TUFF) that were used at baseline. The study included 41 floor layers and 40 carpenters. A medical examination focused on health at the present and during the past 18 years. An extensive exposure assessment made in the initial study included questionnaires, interviews, and measurements. Additional exposure during the follow up period was minor, as explored in interviews at follow up.Results: The entire group of floor layers did not deteriorate significantly more over time than did the carpenters. However, among the oldest subjects (>60 years), only floor layers showed decline in visual memory. Moreover, the most highly exposed floor layers deteriorated significantly more than their referents in visual memory and perceptual speed, and they tended to display larger decrements in motor speed. Significant dose effect relations were found; higher cumulative exposure was associated with decrements in visual episodic memory, perceptual speed and attention, and visuospatial skill.Conclusions: The hypothesis that floor layers would deteriorate more in cognitive performance than their unexposed referents over a period of 18 years was partly supported by the results of this study. The results are consistent with the view that the negative effects of exposure to solvents may interact with the normal aging process, primarily at heavy exposure.
REGULARIZATION OF GENERAL MULTIDIMENSIONAL EPSTEIN ZETA-FUNCTIONS
Authors: ELIZALDE E. , ROMEO A. 
Published: July 2002

We study expressions for the regularization of general multidimensional Epstein zeta-functions of the type [Formula: see text] After reviewing some classical results in the light of the extended proof of zeta-function regularization recently obtained by the authors, approximate but very quickly convergent expressions for these functions are derived. This type of analysis has many interesting applications, e.g. in any quantum field theory defined in a partially compactified Euclidean spacetime or at finite temperature. As an example, we obtain the partition function for the Casimir effect at finite temperature.
PERCUTANEOUS AND LIMITED OPEN REDUCTION OF INTRA-ARTICULAR DISTAL RADIAL FRACTURES
Authors: Geissler William B. , Fernandes Diego 
Published: July 2002

Fluoroscopy monitors intra-articular distal radial fracture reduction and stabilisation. The reduction is guided by traction, ligamentotaxis and manipulation, and when necessary, completed by minimally invasive percutaneous or limited open instrumentation. Kirschner wires effectively splint the reduction until fracture callus is visualised on X-ray. An occasional mini plate is required to buttress a displaced volar medial lunate facet (die punch) fragment into position.First, major metaphyseal articular fragments are approximated to restore the articular surface. Smaller fragments follow their larger counterparts into position or may be ignored (the "Rule of the Majority" or "Vassal Rule"). The repaired metaphysis is then aligned with and stabilised to the diaphysis. Cancellous bone may be inserted through small targeted incisions when defects and areas of comminution are present.The wrist is splinted in a functional (slightly extended) position for three to four weeks in uncomplicated cases. Digital elevation and rehabilitation are emphasised during the early stages of fracture healing. After callus appears on X-ray, progressive wrist rehabilitation is initiated and the patients are weaned from their splints. Minimally invasive surgical intervention, good pain control and early rehabilitation maximise functional recovery and minimise morbidity, medical costs and lost work time.
A STOCHASTIC CASCADE MODEL FOR FX DYNAMICS
Authors: BREYMANN WOLFGANG , GHASHGHAIE SHOALEH , TALKNER PETER 
Published: July 2002

A time series model for the FX dynamics is presented which takes into account structural peculiarities of the market, namely its heterogeneity and an information flow from long to short time horizons. The model emerges from an analogy between FX dynamics and hydrodynamic turbulence. The heterogeneity of the market is modeled in the form of a multiplicative cascade of time scales ranging from several minutes to a few months, analogous to the Kolmogorov cascade in turbulence. The model reproduces well the important empirical characteristics of FX rates for major currencies, as the heavy-tailed distribution of returns, their change in shape with the increasing time interval, and the persistence of volatility.
Tools and transformations—rigorous and otherwise—for practical database design
Authors: Rosenthal Arnon , Reiner David 
Published: July 2002

We describe the tools and theory of a comprehensive system for database design, and show how they work together to support multiple conceptual and logical design processes. The Database Design and Evaluation Workbench (DDEW) system uses a rigorous, information-content-preserving approach to schema transformation, but combines it with heuristics, guess work, and user interactions. The main contribution lies in illustrating how theory was adapted to a practical system, and how the consistency and power of a design system can be increased by use of theory.
First, we explain why a design system needs multiple data models, and how implementation over a unified underlying model reduces redundancy and inconsistency. Second, we present a core set of small but fundamental algorithms that reaarange a schema without changing its information content. From these reusable components, we easily built larger tools and transformations that were still formally justified. Third, we describe heuristic tools that attempt to improve a schema, often by adding missing information. In these tools, unreliable techniques such as normalization and relationship inference are bolstered by system-guided user interactions to remove errors. We present a rigorous criterion for identifying unnecessary relationships, and discuss an interactive view integrator. Last, we examine the relevance of database theory to building these practically motivated tools and contrast the paradigms of system builders with those of theoreticians.
Min-max heaps and generalized priority queues
Authors: Atkinson M. D. , Sack J.-R. , Santoro N. , Strothotte T. 
Published: July 2002

A simple implementation of double-ended priority queues is presented. The proposed structure, called a min-max heap, can be built in linear time; in contrast to conventional heaps, it allows both FindMin and FindMax to be performed in constant time; Insert, DeleteMin, and DeleteMax operations can be performed in logarithmic time.
Min-max heaps can be generalized to support other similar order-statistics operations efficiently (e.g., constant time FindMedian and logarithmic time DeleteMedian); furthermore, the notion of min-max ordering can be extended to other heap-ordered structures, such as leftist trees.
Stakeholders Influence and Internal Championing of Product Stewardship in the Italian Food Packaging Industry
Authors: Braglia Marcello , Petroni Alberto 
Published: July 2002

SummaryEnvironmental management is becoming a top issue on managers' agendas in several industries. The adoption and implementation of a sound “green” strategy involves following product stewardship practices. Product stewardship is the idea that manufacturers, rather than consumers, governments, or waste companies, ought to take responsibility for the recycling and disposal of their products at the end of their life cycle. This article is aimed at investigating the relationships between the adoption of product stewardship practices and the involvement of different actors in the decision‐making process. By means of discriminant analysis, 120 firms have been classified into two different environmental profiles. Results indicate that firms that are more committed to product stewardship differ from less‐committed firms in the influence exerted by different stakeholders and in the supportive role played by the management at different hierarchical and functional levels. In general, it appears that top management involvement in the decision‐making process is a critical condition for the successful championship of product stewardship. In addition, the effective implementation of product stewardship along the product life‐cycle stages is correlated to a strong commitment on the part of chief technical officers and development engineers rather than of manufacturing or marketing managers.
Materials Flow Analysis of the Italian Economy
Authors: de Marco Ottilia , Lagioia Giovanni , Mazzacane Elsa Pizzoli 
Published: July 2002

SummaryThis article analyzes the mass of the materials that flowed through the Italian economy during 1994 and compares the results with a similar analysis of Germany, Japan, the Netherlands, and the United States published by a collaboration headed by the World Resources Institute. In order to perform this comparison, we have evaluated the mass of the materials produced within the country and the mass of the imported materials and commodities. For the domestic production, imports and exports, we have also evaluated the mass of the materials that accompany—as “hidden flows”—each physical flow.Our analysis indicates that, in 1994, Italy experienced total material requirements (TMR) of 1,609 million metric tons (Mt), of which 727 Mt was used as direct material input (DMI). A comparison with other developed countries shows that the TMR and DMI flows, measured in mass per person and in mass per GDP unit, are, in Italy, lower than the corresponding figures evaluated for the United States, Germany, and the Netherlands. An interpretation of these results is presented. The analysis may give information useful for environmental considerations, although the limits of such an approach are made clear.
TEMPORAL PATTERNS OF PARENTAL RESOURCE DISTRIBUTION IN THE RED-NECKED GREBE: EQUALIZING THE SHARE OF THE SURVIVORS
Authors: Kloskowski Janusz 
Published: July 2002

AbstractFood distribution within brood and parental aggression to chicks were studied in the asynchronously hatching red-necked grebe Podiceps grisegena throughout the whole period of parental care. When carrying young - during the first two weeks after hatching - parents did not interfere in sibling competition for food. The proportions of food received by each brood member reflected the dominance hierarchy. After this period, parents showed aggression to offspring, especially to the older chicks and the within-brood hierarchy of received food was gradually reversed. Junior chicks were also longer cared for than their older sibling. Male and female parents did not differ in the food apportionment among differentrank chicks. It is suggested that red-necked grebe parents change the within-brood investment allocation over time. In the first weeks after hatching, they allow biased food distribution and in consequence even brood reduction. Later, they intervene in resource allocation and attempt to equalize the post-fledging survival of all chicks. Parental aggression appears to be a means both for counteracting the competitive advantage of older sibs and for forcing the chicks to independence.
SETT USE IN EUROPEAN BADGERS MELES MELES
Authors: Roper  , Ostler  , Schmid  , Christian  
Published: July 2002

AbstractThe European badger Meles meles constructs burrows of two basic types: 'main setts' and 'outliers'. We examined daytime burrow use year-round in 19 radio-collared badgers belonging to six different social groups, in order to test the hypotheses relating use of multiple sleeping sites to ectoparasite avoidance and social status. Ten animals rarely or never slept away from the main sett, while the remaining nine animals spent 20-73% of their days in outliers, mainly in summer. Outlier use was not related to sex or body condition, but animals that used outliers tended to be younger and had larger numbers of fleas than those that remained in the main sett year-round. Within the main sett, all the members of a social group had overlapping ranges: i.e. the sett was not divided into separate 'territories'. Group ranges were smallest in winter and largest in summer/autumn. Nest chambers were usually shared between at least two members of a social group on any one day, but males slept alone more often than did females. Individuals tended to cluster together in the same nest chamber more in winter than at other times of year, presumably to gain thermoregulatory advantage from huddling. We conclude that the pattern of burrow use in badgers is complex. Use of space within the main sett and tendency to disperse to outliers in the summer are in part affected by ectoparasite infestation, while use of space within the main sett is also influenced by variables such as sex and age that may reflect social status.
DESCRIPTION OF A NEW SPECIES OF SOMANNIATHELPHUSA (DECAPODA, BRACHYURA, PARATHELPHUSIDAE) FROM VIETNAM
Authors: Quynh Nguyen Xuan , Yeo Darren 
Published: July 2002

AbstractA new species of ricefield crab belonging to the genus Somanniathelphusa is described from Hanoi, Vietnam. It is the second Somanniathelphusa species to be described from Hanoi in recent years, differing from its congeners mainly by the form of its G1. Une nouvelle espece de crabe de riziere appartenant au genre Somanniathelphusa est decrite de Hanoi, Vietnam. C'est la seconde espece de Somanniathelphusa a etre decrite de Hanoi au cours des dernieres annees. Elle differe de ses congeneres principalement par la forme de la premiere paire de pleopodes du male.
Mineralogy of the <2 μm fraction of three mixed-layer clays from southern and central Tunisia
Authors: Ben Rhaiem H. , Tessier D. , Ben Haj Amara A. 
Published: July 2002

AbstractThree clay minerals from southern and central Tunisia were characterized. Both XRD quantitative analysis and a chemical method were used to determine the mineralogical and physico-chemical characteristics of the <2 μm clay fractions. The XRD, CEC and specific surface measurement analyses showed that the dominant phase in all samples is illite-smectite with kaolinite and traces of quartz also present. From quantitative XRD, the abundances of the minerals identified are consistent with the measured CEC, specific surface area and TG/DTA properties. Analysis by XRD also showed that the illite-smectite phases are composed of thin stacks (two to a maximum of ten layers per stack) of random illite-smectite and ordered (R1) illite-smectite. There is also some discrete illite.
Distribution and origin of clay minerals in the Lower Cretaceous of the Alava Block (Basque-Cantabrian Basin, Spain)
Authors: Sangüesa F. J. , Arostegui J. , Suarez-Ruiz I. 
Published: July 2002

AbstractLower Cretaceous clay minerals suites of the Alava Block, analysed by XRD, are dominated either by illite or kaolinite. These assemblages are mainly inherited in origin, although textural evidence (SEM) indicates some diagenetic clay. Precipitation of blocky kaolinite took place in sandstones from the southern domain of the Block, characterized by low sedimentation and subsidence rates and by low vitrinite reflectance values (%Rr <0.8). In the northern domain, where sedimentation and subsidence rates were high (%Rr >3.3), illitization of kaolinite and smectitic clays and precipitation of authigenic chlorite occurred. Some chemical aspects of these reactions are discussed.
Paragenesis of Cu-Fe ores from Ocna de Fier-Dognecea (Romania), typifying fluid plume mineralization in a proximal skarn setting
Authors: Cook N. J. , Ciobanu C. L. 
Published: July 2002

AbstractTrace mineral assemblages in the bornite- and chalcopyrite-rich Cu-Fe zone of the Ocna de Fier-Dognecea skarn deposits, Banat, SW Romania provide additional constraints on the genesis of this classic zoned skarn system. Observed assemblages substantiate a model, in which the Cu-Fe zone forms the proximal fluid-plume root of the system. Observed trace mineral assemblages in the magnesian forsterite-bearing skarns crystallized at ~650°C in a volatile-rich environment, evidenced by widespread phlogopite, ludwigite, valleriite and apatite. The entire assemblage thus belongs to the initial stage of skarn formation. Prolonged cooling led to sequential exsolution of trace mineral phases from bornite and chalcopyrite during the retrograde stage, although still at temperatures in excess of 500°C. Bornite is typified by the abundance of exsolved phases along cleavage planes and along crystal margins, notably chalcopyrite and pyrrhotite, but also cobalt pentlandite, carrollite, wittichenite, galena, mawsonite, silver and electrum. Chalcopyrite hosts cobalt pentlandite, carrollite, wittichenite, galena and a sequence of Se- and Te-bearing minerals (kawazulite, bohdanowiczite, hessite, volynskite), along, although not restricted to, grain margins. The assemblage bornite-chalcopyrite-magnetite, with the trace phases, cobalt pentlandite, carrollite, wittichenite and various Se- and Te-bearing minerals represents a characteristic assemblage common to a disparate range of deposits formed at temperatures in excess of 500°C in the presence of volatiles and typified by relatively low fS2 fluids.
Nb-rich brookite from Gross Brukkaros, Namibia: substitution mechanisms and Fe2+/Fe3+ ratios
Authors: Werner M. , Cook N. J. 
Published: July 2002

AbstractIdioblastic, mm-scale brookite is reported from SiO2-Ba-Fe-rich metasomatic rocks from the carbonatitic Gross Brukkaros Volcanic Field, Southern Namibia. Electron probe microanalysis shows significant concentrations of Nb (12–17 wt.% Nb2O5), coupled with Fe, substituting for Ti in the structure. Calculation of the analytical data indicates evolving Fe2+/(Fe2++Fe3+) ratios during crystallization and two distinct substitution mechanisms in operation: 2Ti4+ ⇋ Nb5+ + Fe3+ and 3Ti4+ ⇋ 2Nb5+ + Fe2+. The compositional patterns observed are explained in terms of initial growth in an environment which evolved from oxidizing to reducing. The outermost 10 µm rims of the crystals are characterized by oxidizing conditions, resulting from a subsequent metasomatic overprint.
Cation distribution in natural Zn-aluminate spinels
Authors: Lucchesi S. , Della Giusta A. , Russo U. 
Published: July 2002

AbstractThe intracrystalline cation distributions in fourteen natural Zn-aluminate spinels were determined by means of X-ray single-crystal structural refinement, supported for some samples by Mössbauer spectroscopy.Zinc substitutes for Mg and subordinately Fe2+ and its relevant changes in content, from 0.10 to 0.96 atoms per formula unit (apfu), are not related to variations of cell parameter. The latter is determined mainly by the substitution Fe3+ ⇌ Al. In agreement with data from synthetic samples, a small but definite amount of Zn (up to 0.06 apfu) is located in the octahedral M site. Fe2+, when present, shows a preference for tetrahedral coordination.An improved value of the tetrahedral Zn(T)-O distance (1.960 Å) was obtained, integrating the set of interatomic distances used for the determination of cation distribution in spinels.
Defect structure and luminescence behaviour of agate — results of electron paramagnetic resonance (EPR) and cathodoluminescence (CL) studies
Authors: Götze J. , Plötze M. , Fuchs H. , Habermann D. 
Published: July 2002

AbstractSamples of agate and quartz incrustations from different parent volcanic rocks of certain world-wide localities were investigated by EPR, CL and trace element analysis. In all agate samples the following paramagnetic centres were detected:, E′1, [AlO4]0 [FeO4/M+]0 and [GeO4/M+]0. Centres of the type [TiO4/Li+]0 and [TiO4/H+]0, which were detected in quartz of the parent volcanics, are absent in agate. Generally, the abundance of centres (silicon vacancy) and E′1 centres (oxygen vacancy) in agate is remarkably higher than in quartz. The high defect density in agates points to rapid growth of silica from a strongly supersaturated solution probably with a noncrystalline precursor.CL microscopy reveals internal structures and zoning in agates and quartz incrustations which clearly differ from those discernible by conventional polarizing microscopy. The CL spectra of agates differ from those of quartz from crystalline rocks. At least three broad emission bands were detected in the CL spectra: a blue band of low intensity, a yellow band at about 580 nm, and an intense red band at 650 nm. The CL emission at 650 nm shows some relations to the hydroxyl or alkali content and the abundance of centres and E′1 centres. The emission intensity increases during electron bombardement due to the conversion of different precursors (e.g. ≡Si-O-H, ≡Si-O-Na groups) into hole centres. Another conspicuous feature in the CL spectra of agates is the existence of a yellow emission band centred at around 580 nm. The predominance of the yellow CL emission band and the high concentration of E′1 centres are typical for agates of acidic volcanics and are indicative of a close relationship between the two.