bluuebunny/crossref_metadata_2025_split huggingface dataset:
Treatment of Femoral Neck Fracture with Percutaneous Compression Plate: Preliminary Results in 74 Patients
Authors: Zhu Feng , Liu Gang , Shao Hong‐guo , Wang Yi‐jun , Li Rong‐qun , Yang Hui‐lin , Geng De‐chun , Xu Yao‐zeng 
Published: June 2015

ObjectiveThe purpose of this study was to present the surgical technique and clinical results of percutaneous compression plate (PCCP) for the treatment of femoral neck fractures.MethodsBetween December 2010 and April 2013, 74 consecutive patients with 74 femoral neck fractures were treated by closed reduction and PCCP implants in our university hospital. Their mean age was 51.3 years (range, 15–83 years); 38 (51.4%) were male and 46 (62.2%) of the fractures were on the left. The patients' clinical and radiographic data were analyzed retrospectively.ResultsThere were 45 undisplaced (60.8%) and 29 displaced fractures (39.2%). Eight patients (10.8%) were lost to follow‐up. The mean duration of follow‐up was 18.8 months for the remaining 66 patients. At the last follow‐up, mean Harris hip score was 92.9 (range, 75–100), and 65 patients (98.5%) had excellent and good outcomes. Sixty‐five patients (98.5%) were able to walk independently and one (1.5%) with walking‐sticks. The mean time to clinical fracture healing was 3.9 months. There were no cases of nonunion. Two patients (3.0%) had delayed union and two (3.0%) developed avascular necrosis, one of 29 (3.7%) with a displaced fracture and one of 45 (2.6%) with an undisplaced fracture. There were no other complications or prosthetic replacement.ConclusionsPCCP is a stable internal fixation device that resists axial and rotational stresses. Our PCCP procedure has a low incidence of nonunion and avascular necrosis.
Minimally Invasive Unicompartmental Knee Arthroplasty for Spontaneous Osteonecrosis of the Knee
Authors: Guo Wan‐shou , Zhang Qi‐dong , Liu Zhao‐hui , Cheng Li‐ming , Yue De‐bo , Wang Wei‐guo , Zhang Nian‐fei , Li Zi‐rong 
Published: June 2015

ObjectiveTo explore the outcome and surgical technique of minimally invasive unicompartmental knee arthroplasty (UKA) for spontaneous osteonecrosis of the knee.MethodsTwenty‐seven patients with medial compartmental spontaneous osteonecrosis treated by minimally invasive Oxford phase 3 UKA from January 2009 to June 2013 were reviewed retrospectively. Twelve subjects were men and 15 women, with an average age of 64.6 ± 8.6 years (52–82 years). At the time of diagnosis, 11 patients had with grade III necrosis and 16 grade IV according to Mont's classification. Pain, range of motion (ROM) and Hospital for Special Surgery (HSS) knee scores were evaluated before and after UKA. Pre‐and postoperative alignment of the lower limbs was measured and compared. Postoperative radiographic assessments were made according to the guidelines proposed by the Oxford group at the final follow‐up.ResultsAll patients were followed for a mean time of 27.8 ± 15.9 months (6–59 months). There were no serious adverse events, such as infection, bearing dislocation, aseptic loosening, pulmonary embolism, deep venous thrombosis, cardio‐cerebral vascular incident or psychological problems. One revision was required for unrelated causes (fracture of tibia plateau) 3 years after arthroplasty. One femoral component was tilted with a postoperative radiographic angle >10°. One radiolucent line was observed in a patient with spontaneous osteonecrosis of the knee. The two patients with implant failure had no symptoms at last follow‐up. Visual analogue scale scores decreased from 6.9 ± 0.9 to 2.0 ± 1.1 (t = 19.27, P = 0.00). Pain was relieved in 96.3% of subjects (26/27). The mean post‐operative ROM and femorotibial angle were 125.7° ± 9.6° and 177.7° ± 3.1°, respectively. HSS scores increased from 61.3 ± 9.7 to 93.0 ± 4.8 (t = 14.46, P = 0.00). Of the 27 patients, 26 (96.3%) were satisfied with the outcome of this surgical procedure.ConclusionMinimally invasive UKA is an effective means of managing spontaneous osteonecrosis of the knee. The short‐term outcome of UKA is encouraging.
Surgical Treatment of Acetabulum Top Compression Fracture with Sea Gull Sign
Authors: Zhuang Yan , Lei Jin‐lai , Wei Xing , Lu Dai‐gang , Zhang Kun 
Published: June 2015

ObjectiveTo investigate surgical procedures and their efficacy for acetabulum top compression fractures with sea gull sign.MethodsData of 14 patients (five women, nine men); aged from 28 to 71 years (mean, 49.9 years) who had undergone surgery for acetabulum top compression fractures with sea gull sign and been followed up were retrospectively analyzed. The time from injury to surgery was 4−14 days (mean, 9 days). All patients underwent open reduction and bone graft and internal fixation through an ilioinguinal or ilioinguinal plus Kocher−Langenbeck approach. Quality of fracture reduction was assessed according to Matta reduction criteria and hip function according to Matta acetabular fracture criteria.ResultsFourteen patients were followed up for 6−60 months (mean, 36 months). All achieved bone healing within 3−4 months (mean, 3.4 months); the excellent and good rate being 78.5% (11/14). The Matta acetabular fracture scores were 10−18 scores (mean, 16.4); the excellent and good rate being 71.4% (10/14). Traumatic arthritis occurred in three patients. Pain was serious in two patients and relieved by total hip joint replacement and mild in one. One patient developed asymptomatic heterotopic ossification postoperatively.ConclusionThe appropriate delay between injury and surgery with acetabular roof compression fracture with sea gull sign is from 5 to 10 days. Through an ilioinguinal or ilioinguinal plus Kocher−Langenbeck approach, excellent reduction of the articular surface can be achieved and sufficient bone graft material obtained. The clinical efficacy is satisfactory.
Total Hip Arthroplasty with Subtrochanteric Femoral Shortening Osteotomy for High Hip Dislocation
Authors: Hua Wen‐bin , Yang Shu‐hua , Xu Wei‐hua , Ye Shu‐nan , Liu Xian‐zhe , Wang Jing , Feng Yong 
Published: June 2015

ObjectiveTo evaluate the outcomes of total hip arthroplasty (THA) with subtrochanteric femoral shortening osteotomy for high hip dislocation.MethodsIn this retrospective study, the results of 24 primary THAs with acetabular reconstruction and subtrochanteric femoral shortening osteotomy in 21 patients with high hip dislocation were evaluated. The acetabula were reconstructed with cemented or uncemented cups and bone grafting. Transverse subtrochanteric femoral shortening osteotomies were applied and the osteotomy sites treated by bone grafting and cable fixation. Assessment was by Hip Harris scores and radiographic evaluation.ResultsThe mean follow‐up time was 42 months (18–108 months), three cases being lost to follow‐up 18–27 months postoperatively. The HHS improved from 47.5 ± 8.7 to 88.5 ± 3.1. The mean length of femoral segments removed was 2.5 ± 0.8 cm (range, 1.0–4.5 cm) and mean acetabular inclination 43° ± 5° (range, 31°–54°). Caudalization of the femoral head center was 3.2 ± 3.0 mm (range, −3 to 12 mm) and lateralization 4.0 ± 4.0 mm (range, −9 to 11 mm). Mean greater trochanter height relative to theoretical hip center was 5.2 ± 1.0 cm (range, 3.5–7.1 cm) preoperatively and 0.2 ± 0.6 cm (range, −0.9 to 1.2 cm) postoperatively. Intraoperative trochanteric fractures occurred in three cases and sciatic nerve palsy in one.ConclusionTHA with subtrochanteric femoral shortening osteotomy is an effective technique for treating high hip dislocation. Its advantages include improvement in limb imbalance and decreased risk of sciatic nerve injury.
Effect of Advanced Oxidation Protein Products on Articular Cartilage and Synovium in a Rabbit Osteoarthritis Model
Authors: Yu Hui , Ye Wen‐bin , Zhong Zhao‐ming , Ding Ruo‐ting , Chen Jian‐ting 
Published: June 2015

ObjectiveAdvanced oxidation protein products (AOPPs), a marker of oxidative stress, are prevalent in many kinds of disorders. Osteoarthritis (OA), mainly resulting from the regression of cartilage, chronic inflammation of the synovium and the subchondral bone remodeling. Although the inflammatory response of AOPPs on fibroblast‐like synoviocytes (FLSs) were reported, the effect of AOPPs on cartilage and synovial in vivo remains unclear. Therefore, our study aims to investigate whether AOPPs have an effect on the articular cartilage and synovial in a rabbit model of OA.MethodsOA model were created by anterior cruciate ligament transection and medial meniscus resection (ACLT + MMx). Forty‐eight male New Zealand rabbits were randomly divided into 3 groups: sham‐operated group, AOPPs/ACLT + MMx group, and phosphate buffered saline (PBS)/ACLT + MMx group. In sham‐operated group, the anterior cruciate ligament was just exposed without transection, and then the incision was sutured. Then intra‐articular injection of AOPPs or PBS was performed in the other two groups. Through four weeks and eight weeks of treatment, rabbits in each group were sacrificed. Both hind legs were removed. India ink staining and Safranin O and fast green staining were used to evaluate the macroscopic and microscopic cartilage morphology. The protein expression of matrix metalloproteinases (MMP)‐3, MMP‐13 in synovium was measured by Western blot.ResultThe India ink score and Mankin score of AOPPs/ACLT + MMx group were both higher than the other two groups at the two time points. Western blot have revealed that intra‐articular injection of AOPPs upregulated the protein expression of MMP‐3 and MMP‐13 in synovium.ConclusionAOPPs participated in the occurrence and development of OA by upregulating the protein expression of MMP‐3 and MMP‐13 in synovium.
Postoperative hypoalbuminemia following surgery related to craniosynostosis
Authors: Allison Elizabeth , Evans Russell G. , Wall Steven , Johnson David , Das Sumit 
Published: June 2015

SummaryBackgroundAn episode of postoperative phenytoin toxicity in a patient undergoing surgery related to craniosynostosis highlighted the presence of hypoalbuminemia. We believe that hypoalbuminemia contributed to the altered pharmacokinetics of phenytoin in this case.ObjectivesTo establish the incidence of postoperative hypoalbuminemia in patients undergoing surgery related to craniosynostosis and to investigate the likely etiology.MethodsData on 114 patients undergoing surgery for craniosynostosis over a 2‐year period at Oxford Children's Hospital, between May 2011 and May 2013, were retrospectively reviewed. Twenty‐two patients were excluded due to incomplete data. This cohort represents the entire population for whom transfusion data had been formally collected at our institution. Preoperative and day 1 postoperative serum albumin levels were collected from the hospital laboratory database. Data regarding blood loss and intra‐operative fluid management were reviewed from the anesthetic database. Linear regression analysis was used to establish the relationship between percentage drop in serum albumin with: (i) milliliters per kilogram (ml·kg−1) volume of albumin‐poor fluids used intra‐operatively and (ii) percentage estimated red cell mass loss.ResultsAll patients experienced a statistically significant drop in serum albumin. The mean difference in albumin was 17.1 g·l−1, 95% CI (16.1–18.0) (P < 0.001). Expressed as a percentage, the mean reduction was 37.9% (range 16–61%), SD 9.7. The decrease in albumin was associated with an increase in estimated red cell mass loss (P < 0.001) and an increased ml·kg−1 volume of albumin‐poor fluids given (P < 0.001).ConclusionHemodilution due to large volume blood loss and transfusion with albumin‐poor fluids is strongly associated with postoperative hypoalbuminemia in patients undergoing surgery related to craniosynostosis. Practitioners should be aware of this risk and the implications of postoperative hypoalbuminemia in this population.
Dutch Multidisciplinary Guideline for Invasive Treatment of Pain Syndromes of the Lumbosacral Spine
Authors: Itz Coen J. , Willems Paul C. , Zeilstra Dick J. , Huygen Frank J. 
Published: June 2015

AbstractObjectivesWhen conservative therapies such as pain medication or exercise therapy fail, invasive treatment may be indicated for patients with lumbosacral spinal pain. The Dutch Society of Anesthesiologists, in collaboration with the Dutch Orthopedic Association and the Dutch Neurosurgical Society, has taken the initiative to develop the guideline “Spinal low back pain,” which describes the evidence regarding diagnostics and invasive treatment of the most common spinal low back pain syndromes, that is, facet joint pain, sacroiliac joint pain, coccygodynia, pain originating from the intervertebral disk, and failed back surgery syndrome.MethodsThe aim of the guideline is to determine which invasive treatment intervention is preferred for each included pain syndrome when conservative treatment has failed. Diagnostic studies were evaluated using the EBRO criteria, and studies on therapies were evaluated with the Grading of Recommendations Assessment, Development and Evaluation system. For the evaluation of invasive treatment options, the guideline committee decided that the outcome measures of pain, function, and quality of life were most important.ResultsThe definition, epidemiology, pathophysiological mechanism, diagnostics, and recommendations for invasive therapy for each of the spinal back pain syndromes are reported.DiscussionThe guideline committee concluded that the categorization of low back pain into merely specific or nonspecific gives insufficient insight into the low back pain problem and does not adequately reflect which therapy is effective for the underlying disorder of a pain syndrome. Based on the guideline “Spinal low back pain,” facet joint pain, pain of the sacroiliac joint, and disk pain will be part of a planned nationwide cost‐effectiveness study.
Respiratory Sinus Arrhythmia and its Association with Pain in Women with Fibromyalgia Syndrome
Authors: Zamunér Antonio R , Forti Meire , Andrade Carolina P , Avila Mariana Arias , da Silva Ester 
Published: June 2015

AbstractObjectivesTo assess the cardiac autonomic control at rest and during the deep breathing test (DBT) and its association with pain in women with fibromyalgia syndrome (FMS).MethodsThe study included 20 women with FMS and 20 healthy women (control group, CG). The pain was quantified by assessing the pressure pain threshold (PPT), VAS of pain, and the pain component of the SF‐36 questionnaire. The RR intervals were recorded in the supine position and during the DBT. The heart rate variability (VHR) was measured by methods in the time and frequency domain.ResultsThe group with FMS had abnormal cardiac autonomic modulation at rest and during DBT, compared to CG (P < 0.05). Positive correlations were found between PPT and the E/I ratio (r = 0.70), ΔFC (r = 0.66) and power spectrum density (DEP, r = 0.56) indices of DBT, as well as between pain component of the SF‐36 and the E/I ratio (r = 0.49), ΔFC (r = 0.45) and DEP (r = 0.50) indices of DBT. Significant correlations were observed between the FIQ questionnaire and the LF/HF ratio index in the supine position and the E/I ratio (r = −0.63), ΔFC (r = −0.54), and DEP (r = −0.51) indices of DBT.ConclusionsThe results of VHR indices during the supine position and the DBT women with FMS suggest impairment of neurocardiac integrity associated with pain and the impact of FMS on the quality of life.
Longitudinal association between habitual physical activity and depressive symptoms in older people
Authors: Yoshida Yuko , Iwasa Hajime , Kumagai Shu , Suzuki Takao , Awata Shuichi , Yoshida Hideyo 
Published: June 2015

AimsPrevention of depressive symptoms is an essential issue with regard to the promotion of healthy lifestyles in older people. To date, few studies have examined the relation between fluctuations in physical activity and depression among older individuals. We thus conducted a longitudinal survey of older adults to examine the effect of long‐term fluctuating physical activity on the incidence of depressive symptoms.MethodsA 3‐year prospective cohort study was performed in a community‐based environment. A total of 680 individuals (291 men and 389 women) aged 65 years and over at the baseline assessment participated. The 15‐item Geriatric Depression Scale was used to assess depressive symptoms, with scores of ≥6 indicative of depression. Participants were categorized into the following four groups based on change in physical activity status between 2002 and 2003: sedentary, cessation, initiation, and maintenance.ResultsThe incidence of depressive symptoms was 16.9% (16.8% in men and 17.0% in women) at the 3‐year follow up (in 2006). Multiple logistic regression analyses showed that physical activity maintenance (odds ratio, 0.50; 95% confidence interval, 0.30–0.83) only reduced the incidence of depressive symptoms at the 3‐year follow up after adjusting for confounding variables.ConclusionsContinuous physical activity may be a valuable and simple way to prevent depressive symptoms in community‐dwelling older people. Therefore, it is necessary to implement interventions that teach older adults how to integrate physical activity into their daily lives.
Evaluating along‐strike variation using thin‐bedded facies analysis, Upper Cretaceous Ferron Notom Delta, Utah
Authors: Li Zhiyang , Bhattacharya Janok , Schieber Juergen 
Published: June 2015

AbstractThin‐bedded delta‐front and prodelta facies of the Upper Cretaceous Ferron Notom Delta Complex near Hanksville in southern Utah, USA, show significant along‐strike facies variability. Primary initiation processes that form these thin beds include surge‐type turbidity currents, hyperpycnal flows and storm surges. The relative proportion of sedimentary structures generated by each of these depositional processes/events has been calculated from a series of measured sedimentological sections within a single parasequence (PS6–1) which is exposed continuously along depositional strike. For each measured section, sedimentological data including grain size, lithology, bedding thickness, sedimentary structures and ichnological suites have been documented. Parasequence 6–1 shows a strong along‐strike variation with a wave‐dominated environment in the north, passing abruptly into a fluvial‐dominated area, then to an environment with varying degrees of fluvial and wave influence southward, and back to a wave‐dominated environment further to the south‐east. The lateral facies variations integrated with palaeocurrent data indicate that parasequence 6–1 is deposited as a storm‐dominated symmetrical delta with a large river‐dominated bayhead system linked to an updip fluvial feeder valley. This article indicates that it is practical to quantify the relative importance of depositional processes and determine the along‐strike variation within an ancient delta system using thin‐bedded facies analysis. The wide range of vertical stratification and grading sequences present in these event beds also allows construction of conceptual models of deposition from turbidity currents (i.e. surge‐type turbidity currents and hyperpycnal flows) and storm surges, and shows that there are significant interactions and linkages of these often paired processes.
From Normative Influence to Social Pressure: How Relevant Others Affect Whether Bystanders Join in Cyberbullying
Authors: Bastiaensens Sara , Pabian Sara , Vandebosch Heidi , Poels Karolien , Van Cleemput Katrien , DeSmet Ann , De Bourdeaudhuij Ilse 
Published: June 2015

AbstractAs cyberbullying is a phenomenon that is inherently social, the normative social influence of significant others can play an important role in the behaviour of adolescents involved in cyberbullying incidents. Using data from 525 adolescent bystanders of cyberbullying, we created a path model in order to investigate whether injunctive and descriptive norms of certain reference groups can cause bystanders to experience social pressure and join in cyberbullying. The results showed that social pressure fully mediated the relationship between the injunctive norm of friends approving of cyberbullying and joining in cyberbullying as a bystander. Furthermore, both the injunctive norm of parents approving of cyberbullying and bystanders’ involvement in cyberbullying perpetration were related to joining in cyberbullying as a bystander.
Platelet‐derived extracellular vesicles in plateletpheresis concentrates as a quality control approach
Authors: Black Anne , Pienimaeki‐Roemer Annika , Kenyon Oliver , Orsó Evelyn , Schmitz Gerd 
Published: June 2015

BACKGROUNDPlatelet‐derived extracellular vesicles (PL‐EVs) are present in plateletpheresis concentrates (PCs) and may influence the quality of PCs. The aim of the study was to analyze PC‐derived PL‐EVs and to correlate them with standard quality control (QC) variables of PCs and with donor‐specific laboratory variables.STUDY DESIGN AND METHODSPL‐EVs were analyzed by standard as well as advanced high‐sensitivity flow cytometry (FCM) and nanoparticle tracking analysis. A hematology analyzer was applied to the determination of platelet (PLT) count and immature PLT fraction (IPF). Functional capacity of PLTs (CD62P in response to thrombin receptor‐activating peptide 6 activation) was measured by FCM. All in vitro measurements were carried out on Day 0 and on Day 5. Altogether, a total of 42 PC samples, 15 irradiated on Day 0, were investigated.RESULTSExternalization of CD62P, as an indicator of intact PLT function, significantly decreased during in vitro PLT senescence and CD62P expression inversely correlated with increased PL‐EV levels. Interestingly, in fresh PCs a significant correlation was found between PL‐EVs and different hemapheresis instruments, duration of apheresis, and IPF count in peripheral blood of the donor before apheresis. In senescent PCs, the body mass index of donors inversely correlated with the PL‐EV counts.CONCLUSIONLoss of PLT function in PCs was associated with increased PL‐EV levels. Shedding of PL‐EVs depends on shear stress influenced by different hemapheresis settings and diverse preanalytical conditions of donors. PL‐EV analysis may stimulate new quality and apheresis strategies for more vital PLTs for transfusion.
Single‐Incision Laparoscopic Sterilization of the Cheetah (Acinonyx jubatus)
Authors: Hartman Marthinus J. , Monnet Eric , Kirberger Robert M. , Schmidt‐Küntzel Anne , Schulman Martin L. , Stander Jana A. , Stegmann George F. , Schoeman Johan P. 
Published: June 2015

ObjectiveTo describe laparoscopic ovariectomy and salpingectomy in the cheetah (Acinonyx jubatus) using single‐incision laparoscopic surgery (SILS).Study DesignProspective cohort.AnimalsFemale cheetahs (Acinonyx jubatus) (n = 21).MethodsCheetahs were randomly divided to receive either ovariectomy (n = 11) or salpingectomy (n = 10). The use and complications of a SILS port was evaluated in all of cheetahs. Surgery duration and insufflation volumes of carbon dioxide (CO2) were recorded and compared across procedures.ResultsLaparoscopic ovariectomy and salpingectomy were performed without complications using a SILS port. The poorly‐developed mesosalpinx and ovarian bursa facilitated access to the uterine tube for salpingectomy in the cheetah. The median surgery duration for ovariectomy was 24 minutes (interquartile range 3) and for salpingectomy was 19.5 minutes (interquartile range 3) (P = .005). The median volume of CO2 used for ovariectomy was 11.25 L (interquartile range 3.08) and for salpingectomy was 4.90 L (interquartile range 2.52), (P = .001)ConclusionsLaparoscopic ovariectomy and salpingectomy can be performed in the cheetah using SILS without perioperative complications. Salpingectomy is faster than ovariectomy and requires less total CO2 for insufflation.