bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effective strategy for distinguishing raw and vinegar Schisandrae Chinensis Fructus based on electronic eye and electronic tongue combined with chemometrics
Authors: Wang Lixia , Liu Kaiyang , Wu Tong , Chen Xiaoxu , Chen Yingying , Yue Chunyu , Wang Zhuju , Wu Hongwei , Tang Liying 
Published: August 2024

AbstractIntroductionSchisandrae Chinensis Fructus (SCF), a traditional Chinese medicine, has been used in treating virtual injury and strain since ancient times. The Chinese Pharmacopoeia reveals that SCF includes raw (RSCF) and vinegar‐processed (VSCF) decoction pieces.ObjectiveThis study developed an effective method combining the electronic eye (e‐eye), electronic tongue (e‐tongue), and chemometrics to discriminate RSCF and VSCF from the perspective of chemical composition, color, and taste.Material and methodsFirst, RSCF were collected and processed into VSCF, and their color parameters, e‐tongue sensory properties, high‐performance liquid chromatography (HPLC) and ultra‐HPLC (UPLC) characteristic fingerprints, and nominal ingredients were determined. Multivariate statistical analyses, including principal component, linear discriminant, similarity, and partial least squares discriminant analyses, were conducted.ResultsHPLC and UPLC fingerprints were established, demonstrating a > 0.900 similarity. The content determination indicated increased schisantherin A, schisantherin B, and schisandrin A contents in VSCF. The e‐eye data demonstrated a > 1.5 total color difference before and after processing ΔE*ab, indicating the significantly changed sample color and appearance before and after processing. The e‐tongue technology was used to quantitatively characterize the taste of RSCF and VSCF. The t‐test revealed significantly reduced sourness, aftertaste‐bitter, and aftertaste‐astringent values of SCF after vinegar processing. Principal component and partial least squares discriminant analyses indicated that e‐eye and e‐tongue realize the rapid RSCF and VSCF identification.ConclusionThe proposed comprehensive strategy of electronic eye and electronic tongue combined with chemometrics demonstrated satisfactory results with high efficiency, accuracy, and reliability. This can be developed into a novel and accurate method for discriminating RSCF and VSCF.
Effectiveness of early rehabilitation interventions in patients with traumatic brain injury using a large database
Authors: Hayashi Shota , Kamo Tomohiko , Momosaki Ryo 
Published: August 2024

AbstractBackgroundRehabilitation is important for patients with moderate‐to‐severe traumatic brain injury (TBI). However, the timing of early rehabilitation initiation is ambiguous, and its safety and effectiveness are unknown.ObjectiveTo examine the effectiveness and safety of early rehabilitation in patients with moderate‐to‐severe TBI using propensity score analysis and a large database.DesignRetrospective cohort study.SettingA large medical database (JMDC database) of tertiary care facilities was used to compare outcomes of early and delayed rehabilitation.PatientsPatients aged between 20 and 90 years who were diagnosed with TBI were admitted to acute care hospitals. Inclusion criteria were patients undergoing rehabilitation within 7 days of admission with a Glasgow Coma Scale score of 3 to 12 on admission. This study included 3074 patients with moderate‐to‐severe TBI.InterventionsPatients were classified into an early rehabilitation group (within 2 days of admission) or a delayed rehabilitation group (3 to 7 days postadmission), depending on when rehabilitation started after TBI. Rehabilitation was defined as any type or intensity of intervention provided by a physical, occupational, and/or speech/language therapist. Interventions were not controlled.Main Outcome Measure(s)The primary outcome was Barthel Index (BI) efficiency (BI gain/length of stay). Secondary outcomes included BI gain (discharge BI − admission BI), incidence of aspiration pneumonia complications during hospitalization, discharge to home, mortality, and length of stay.ResultsAfter applying inverse probability weighting with propensity scores, the total was 6152 patients. 3074 (50.0%) patients received early rehabilitation. The early rehabilitation group showed no difference in inpatient mortality (p = .438), improved BI efficiency (β = 0.86, p < .001), and shorter length of stay (β = −5.00, p = .018).ConclusionsEarly rehabilitation in patients with moderate‐to‐severe TBI is associated with more efficient functional improvement and reduced hospital stays without an increase in inpatient mortality.
Overnutrition in persons with cystic fibrosis on modulator therapy and the relationship to obstructive sleep apnea
Authors: Jobanputra Aesha M. , Kesavarapu Keerthana , Naik Sreelatha , Ramagopal Maya , Scharf Matthew T. , Jagpal Sugeet 
Published: August 2024

AbstractCystic fibrosis (CF) care is evolving with the ubiquitous use of modulator therapy and resultant increase in lifespan. It is important for CF clinicians to monitor the pathologic weight gain that is concomitantly being seen as obesity is a known risk factor for multiple other diseases. In this review we focus on obesity in CF, discuss screening and lifestyle considerations, outline CF‐specific concerns with weight loss medications, and describe the vicious cycle of obesity and obstructive sleep apnea (OSA). We discuss screening and treatment for OSA, as it directly correlates with weight fluctuation. We offer interim recommendations for CF teams as they continue to care for this population.
Advanced cystic fibrosis liver disease: Endovascular, endoscopic, radiologic, and surgical considerations
Authors: Palle Sirish K. , Leung Daniel H. 
Published: August 2024

AbstractUp to 90% of people with CF (pwCF) will have some form of hepatobiliary involvement. This manuscript aims to explore the different endovascular, endoscopic, radiological and surgical procedures available to diagnose and manage the most severe form of CF hepatobiliary involvement (CFHBI) known as advanced cystic fibrosis liver disease (aCFLD), seen in 10% of pwCF. These procedures and interventions include liver biopsy, hepatic venous pressure gradient measurement, gastrostomy tube placement to optimize nutrition, paracentesis, endoscopic variceal control of bleeding and portosystemic shunting before liver transplantation. By utilizing advanced diagnostic or surgical techniques, healthcare professionals of pwCF can more effectively manage patients with CFHBI and aCFLD and potentially improve patient outcomes.
Transnational social fields of Italian Bangladeshis in Europe and beyond: Towards a new geography of ways of belonging
Authors: Morad Mohammad , Sacchetto Devi , Ansar Anas 
Published: August 2024

AbstractIn view of the growing onward migration and multisited transnationalism among naturalized EU citizens, this article seeks to advance the current understanding of transnational social fields, cataloguing the complex interplays of migrants' ways of being, belonging, and in‐betweenness across different places and spaces. Drawing on multisited qualitative research with Italian Bangladeshis in Italy and the United Kingdom, the paper presents how their ‘ways of being’ are expressed by maintaining transnational attachments to the country of origin and the wider Bangladeshi diaspora. In addition, they maintain transnational ‘ways of belonging’ by incorporating the Bengali language, culture, traditions, and values, and transmitting them to the next generation. Beyond these multiplicities of being and belonging, the findings put forward two important, yet contrasting, observations. On the one hand, there is an ongoing pursuit of onward migration to the UK among a section of the community—often influenced by social networks and transnational connections with the recognised Bangladeshi diaspora in the UK. Apart from being in the ‘community comfort zone’ and language advantage in the integration process, many migrants perceive living in the UK as having a higher ‘prestige’, ‘class’ or ‘status’ vis‐a‐vis Italy in terms of life quality, wealth, cultural, and religious freedom. On the other hand, another cohort is emotionally and culturally embedded in Italian societies and is in a dilemma of whether to migrate onward. In this process, they constantly blend, shift, and negotiate their ways of belonging. The findings unfold how a new geography of belonging takes shape, characterised by fluidities, multifaceted identities, and everyday life practices in a transnational space.
Towards carbon neutral cities: An insight for Istanbul, Turkey
Authors: Gursoy Haksevenler Betul Hande 
Published: August 2024

AbstractTurkey pledged net‐zero emissions by 2053 under the Paris Agreement. Istanbul, its largest city, aims to be carbon‐neutral by 2050. To accomplish this goal, the first step involves identifying emissions and devising reduction plans, with a focus on utilizing natural carbon sinks. This study assessed emissions and potential reductions across Istanbul's 39 districts. Greenhouse gas emissions were calculated using Intergovernmental Panel on Climate Change guidelines. Despite limited data on sink efficacy, a practical approach was adopted. According to the results, Istanbul emitted 58.5 million tons of CO2 equivalent, varying by district in 2022. In Istanbul, 32% of emissions come from electricity consumption, 29% from heating, 29% from transportation, and 10% from waste disposal. High emissions were observed near waste sites or airports. Carbon sinks reduced emissions by 11.5%, with only two districts achieving neutrality. Natural processes alone are not enough; urgent reduction strategies are needed, prioritizing high‐emission districts over citywide measures.
Combined Experimental and Theoretical Investigation of the Electrochemical Behavior of Hydroxy‐Substituted Anils
Authors: Priyambada Biswal Supriya , Hota Prabhudatta , Ranjan Dash Manas , Kumari Misra Pramila 
Published: August 2024

AbstractThe present work explored the electrochemical behavior of two organic compounds, o‐hydroxybenzylidene‐orthochloroaniline(Anil‐1) and o‐hydroxynaphthalidene‐orthochloro aniline(Anil‐2) through a series of theoretical and experimental investigations. The vibrational frequencies of two anilswere analyzed experimentally by FTIR and theoretically by DFT studies. A comparison of the frequencies with their unsubstituted analog, o‐hydroxybenzylideneaniline, confirmed the electron‐donating nature of the −Cl and −OH substituents in anils. The hyperconjugative interaction energy obtained from NBO analysis divulged the direction of the electron donation from the donor orbitals to the acceptor orbitals. UV‐visible studies illustrated prominent π→π* electronic transitions with significant oscillator strength(0.10–0.26) and molar extinction coefficient(~104) experimentally. Analysis of the global and local reactive descriptors of anils revealed a lower HOMO‐LUMO energy gap of Anil‐2(4.05 eV) than Anil‐1(4.46 eV), corroborating the order of decreasing reactivity to be Anil‐2>Anil‐1. The Cyclic Voltammetry studies disclosed the involvement of an oxidation process in Anil‐1 and Anil‐2 with a higher oxidation potential of Anil‐1 (1.43 V) than Anil‐2(1.31 V) due to the naphthyl moiety of the latter. However, the absence of a cathodic peak in both cases envisaged the irreversible nature of oxidation. The results demonstrated that both the anils could be suitable optical materials for microelectronics applications.
Synthesis of 2‐Aminobenzothiazoles via Nickel‐Catalyzed Tandem Reaction of 2‐Bromophenylisothiocyante with Amines
Authors: Philip Rose Mary , Saranya Padinjare Veetil , Anilkumar Gopinathan 
Published: August 2024

AbstractA tandem strategy for the synthesis of 2‐aminobenzothiazoles from 2‐bromophenylisothiocyanate and amines is reported. The reaction occurred efficiently in presence of Ni(acac)2 as the catalyst precursor and ethanol as the solvent. A wide range of aliphatic amines including linear, branched, and cyclic primary and secondary amines proved potential substrates to construct diverse 2‐aminobenzothiazole derivatives in good yields. The reaction is thought to proceed via the formation of a thiourea intermediate and a sequential nickel‐catalyzed C−S bond formation.
Enthalpies of Mixing in Al−Ce−Co Liquid Alloys
Authors: Usenko Natalia , Ivanov Michael , Kotova Natalia 
Published: August 2024

AbstractThe enthalpies of mixing in liquid alloys of the ternary Al−Ce−Co system were determined along four sections (with a constant mole fraction ratio xCe/xCo=0.77/0.23 and xCe/xCo=0.35/0.65 up to xAl=0.2 at 1700 K; with xAl/xCo=0.76/0.24 up to xCe=0.3 and xAl/xCe=0.30/0.70 up to xCo=0.23 at 1823 K) via isoperibolic calorimetry. The enthalpies of mixing in the liquid Al−Ce−Co alloys are large exothermic values. A comparison of the experimentally obtained results for the enthalpies of mixing of liquid alloys and those calculated by the regular Redlich‐Kister‐Muggianu model, taking into account only the data for binary constituent systems, indicates the specific exothermic ‘ternary’ contribution to the energy of formation of Al−Ce−Co ternary alloys. Data on the partial enthalpy of mixing of cobalt at infinite dilution indicate the involvement of cerium 4 f‐electron in the process of alloy formation.
New Benzylidene‐Triazole Tethered Coumarin Molecular Hybrids: Synthesis, SAR, Molecular Modelling Simulations Targeting Tubulin α/β Dimer and its Antimicrobial Evaluation
Authors: Manda Raja Rameshu , Nadh Ratnakaram Venkata , Angajala Gangadhara , Viveka Tella Lakshmi , Aruna Valmiki 
Published: August 2024

AbstractA series of new 7‐{3‐[3‐(Benzylidene‐amino)‐[1,2,4]triazole‐1‐yl]‐propoxy}‐4‐methyl‐chromen‐2‐one molecular hybrids 7(a–k) were synthesized using molecular hybridization approach. The synthesized new benzylidene‐triazole tethered coumarin molecular hybrids were characterized by spectroscopic studies and elemental analysis. The coumarin molecular hybrids have been explored for their antifungal efficacy in terms of tubulin inhibitors using molecular modelling studies against tubulin alphabeta hetero dimer protein. The results clearly demonstrated strong binding affinity of coumarin molecular hybrids with indole substituted and 2,4‐dihydroxy substituted as antagonists with respective binding scores of −10.5 and −10.7 kcal/mol towards tubulin alphabeta hetero dimer protein which was higher in comparison to standards griseofulvin (−8.2 kcal/mol) and fluconazole (−8.1 kcal/mol). In addition, broth dilution method was used to conduct in‐vitro antifungal studies against three fungal strains namely Candida albicans, Aspergillus niger and Aspergillus fumigatus. The results obtained clearly illustrate the antifungal activity of indole and 2,4‐dihydroxy substituted compounds which are consistent with docking simulations. Out of all the synthesized molecular hybrids, indole and 2,4‐dihydroxy substituted compounds depict outstanding antifungal activity with Minimum Inhibitory Concentration (MIC) value of 31.25 μg/ml and 62.5 μg/ml towards C.albicans and with MIC value of 31.25 for both these molecules towards A.niger in each case which is quite higher than griseofulvin and fluconazole respectively. Present work clearly demonstrates the potential efficacy of synthesized indole and 2,4‐dihydroxy substituted coumarin molecular hybrids to be considered as lead compounds for the development of new agents against resistant strains for the treatment of fungal infection.
Asymmetric Synthesis of Full Substituted Cyclohexa‐1,3‐dienes via Organocatalyzed Cascade Michael‐Cyclization of α, α‐Dicyanoalkenes with Nitroolefins
Authors: Cao Ling‐Feng , Yin Yue , Xie Yun‐Long , Xie Jian‐Wu 
Published: August 2024

AbstractAn efficient organocatalytic cascade vinylogous Michael‐cyclization to construct the challenging full substituted cyclohexa‐1,3‐dienes has been developed. Catalyzed by the cinchona alkaloids‐derived thiourea VIII at −60 °C, the products were obtained as a single diastereomer with two contiguous stereocenters and more than four different useful functional groups in moderate to good yields and good to excellent enantioselectivities.
tert‐Butyl Hydroperoxide (TBHP): Recent Progress in C−H Functionalization and Heteroatom‐Heteroatom Bond Formations
Authors: Varala Ravi , Seema Vittal , Hussein Mohamed , Alam Mohammed Mujahid , Beda Durga Prasad 
Published: August 2024

Abstracttert‐Butyl hydroperoxide (tBuOOH, TBHP) is a commonly used hydroperoxide in many oxidation processes. The primary factors contributing to the increasing usefulness of TBHP include its affordability, eco‐friendliness, exceptional efficacy, and capacity to substitute harmful or rare heavy metal oxidants. In this sexennial update, we thoroughly and critically examined the most noteworthy applications of TBHP in C−H functionalization and heteroatom‐heteroatom bond formation reactions from 2018 till the present. The review has been subdivided based on the nature of the bonds being formed. The review focuses on the advantages and disadvantages of using synthetic organic transformations, as well as the breadth of their use and the underlying mechanisms involved.
Two Aggregation‐Induced Emission Actives Triphenylamine‐Based Salicylaldimine Compounds for Latent Fingerprints Detection
Authors: Du Yusong , Tian Jiazhuang , Jiang Xiaozhou , Chen Chunlin , Yang Yanhua , Gao Shulin 
Published: August 2024

AbstractTo further explore the candidate materials for latent fingerprints detection, two triphenylamine‐based salicylaldimine compounds containing phenoxazine moiety (TPA‐PXZ) and carbazole unit (TPA‐Cz) were designed and successfully synthesized, respectively. They exhibited intramolecular charge transfer transitions and aggregation‐induced emission properties. Based on quantum chemical calculation results, it was found that compounds TPA‐Cz and TPA‐PXZ had twisted spatial configuration, which were responsible for aggregation‐induced emission. Meanwhile, the morphology of two compounds nano‐aggregates in the THF/water mixtures with 60 % and 80 % water content was tested. To our delight, the developers that prepared by compounds TPA‐Cz and TPA‐PXZ both were used for latent fingerprints detection on the surface of glasses, and they emitted purple fluorescence, as well as the distinct fingerprint imaging could be easily distinguished fingerprint level 1–3 details. We believe that TPA‐Cz and TPA‐PXZ both are the promising candidate for latent fingerprints detection.
Computational Investigations on Bis‐(ferrocenylmethyl)‐Based Sulphur Rich Sensitizers for Dye‐Sensitized Solar Cells
Authors: Singh Santosh Kumar , Mandal Sudip , Kushwaha Suman 
Published: August 2024

AbstractIn this work, a computational investigation of ferrocene (Fc)‐based compounds FcCH2CS3CH2Fc (1) and FcCH2SSCH2Fc (2) sensitizer for dye‐sensitized solar cells (DSSCs) has been carried out to comprehend the photophysical and photo‐electrochemical properties. The density functional theory (DFT) and time‐dependent DFT (TD‐DFT) were employed to assess the photovoltaic parameters of the compounds. The frontier molecular orbital analysis revealed the electron density distribution at HOMO and LUMO, which clearly demonstrates the charge separation within the compounds. The electronic absorption spectra are simulated using the TD‐DFT method to comprehend the ability of the compounds to harvest sunlight and efficiently act as photosensitizer. Simulation of electronic spectra of dye@TiO2 cluster exhibits that the absorption coefficient of compound 1 is higher than compound 2 due to the greater extent of charge transfer from the dye to the TiO2 cluster. These computational findings are corroborated by the reported photovoltaic performance of the compounds.
Synthesis and Characterizations of BiFeO3 Nanoparticles for Photocatalytic Application
Authors: Anburaja Ranjith , Shaik Kaleemulla 
Published: August 2024

AbstractBismuth ferrite (BiFeO3) nanoparticles were synthesized using sol‐gel method and annealed at 450 °C, 550 °C, 650 °C, and 750 °C for 2 hours. The role of annealing temperature on structural, optical, magnetic, and dielectric properties of BiFeO3 nanoparticles was studied. XRD patterns of BiFeO3 nanoparticles confirm the rhombohedral structure with a mean crystallite size of 40 nm. The optical bandgap of the BiFeO3 nanoparticles increased from 1.9 eV to 2.02 eV with annealing temperature. From photoluminescence spectra, it was observed that the BiFeO3 nanoparticles showed a clear emission peak at 565 nm and its intensity decreased with annealing temperature. Magnetic properties of the BiFeO3 nanoparticles were studied at room temperature and different magnetic behaviours were found in BiFeO3 nanoparticles. The BiFeO3 nanoparticles exhibited ferromagnetism at low annealing temperatures and diamagnetic nature at high annealing temperatures. The AC conductivity studies showed that BiFeO3 nanoparticles possess a dielectric constant of 170 with the least dielectric loss. The BiFeO3 nanoparticles annealed at 750 °C were studied for photocatalytic properties and showed good photocatalytic activity in the visible region. A prominent absorption peak at 663 nm in absorption spectra due to MB and it confirm the utility of BFO as photocatalyst applications.
The competitive dynamics of strategic risk‐taking, unethical behavior, and entry
Authors: Ostler James 
Published: August 2024

AbstractResearch SummaryThis article argues that strategic risk‐taking in the form of unethical behavior can lead to successful entry and that this entry can drive incumbents to either adopt similar behavior or potentially be forced out of the market. Thus, entrepreneurs can introduce innovative, but socially destructive, behavior to a market and motivate its adoption by incumbents. Empirical support is found using a policy change in the liver transplant market to identify the use and adoption of unethical misrepresentation of patient health status. This article contributes to our understanding of entrepreneurial strategy as well as the competitive dynamics between entrants and incumbents in adopting new risky innovations and, in particular, unethical behaviors.Managerial SummaryThis article highlights the impact of strategic risk‐taking through unethical practices, showing how they can sometimes lead to a successful market entry. Successful entry can force existing market players to either follow suit or risk being forced out of the market. This study looks at the liver transplant market, where transplant centers took advantage of a previous policy by misrepresenting patient health status to move their patients to the top of the transplant list. The findings underscore the importance of understanding the competitive dynamics of adopting innovative yet ethically questionable strategies by both new entrants and established companies, offering valuable insights into how businesses navigate competitive pressures and ethical boundaries. It also highlights the importance of policymakers considering these competitive dynamics when setting policy.