bluuebunny/crossref_metadata_2025_split huggingface dataset:
Histological variability in fossil and recent alligatoroid osteoderms: Systematic and functional implications
Authors: Burns Michael E. , Vickaryous Matthew K. , Currie Philip J. 
Published: February 2013

AbstractStatements about morphological variation in extinct taxa often suffer from insufficient sampling that can be remedied by taking advantage of larger sample sizes provided by related, extant taxa. This analysis quantitatively and qualitatively examines histological and morphological variation of osteoderms from extant and extinct alligatoroid specimens. Statistically significant differences were correlated with changes in osteoderm size and shape. These differences are independent of position on the body, taxonomy, or evolution. Histological variation in alligatoroid osteoderms is due to morphological constraints on the elements themselves, and not taxonomic differences. This has implications for the recognition of histological characters in the osteoderms of extinct archosaur groups that lack extant representatives. J. Morphol., 2013. © 2013 Wiley Periodicals, Inc.
Aggressive locoregional management of recurrent peritoneal sarcomatosis
Authors: Baumgartner Joel M. , Ahrendt Steven A. , Pingpank James F. , Holtzman Matthew P. , Ramalingam Lekshmi , Jones Heather L. , Zureikat Amer H. , Zeh Herbert J. , Bartlett David L. , Choudry Haroon A. 
Published: February 2013

AbstractBackgroundand Objectives Peritoneal sarcomatosis responds poorly to systemic chemotherapy and demonstrates high rates of recurrence after resection. We sought to determine perioperative and oncologic outcomes after cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemoperfusion (HIPEC) for recurrent sarcomatosis.MethodsWe reviewed 15 patients undergoing 17 CRS/HIPEC for recurrent sarcomatosis from a prospective database.ResultsThere were four synovial cell sarcomas, five liposarcomas, three leiomyosarcomas, two gastrointestinal stromal tumors (GIST), and three other sarcomas. Adequate cytoreduction (CC‐0/1) was achieved in all patients, with a median intra‐operative Simplified Peritoneal Carcinomatosis Index of 6 (range: 3–9). Median blood loss and operative time were 1 L (range: 450–5,200) and 402 min (range: 324–680), respectively. Chemoperfusion drug was mitomycin C, cisplatin, or doxorubicin. Significant post‐operative complications (Clavien–Dindo III/IV) occurred in four (24%) patients, with no 60‐day mortalities and three (18%) 60‐day re‐admissions. Median intra‐abdominal disease‐free and overall survival after CRS/HIPEC was 17.2 (95% CI: 2.4–19.7 months) and 22.6 months (95% CI: 6.1–62.6 months), respectively. There was a trend towards delayed recurrence after combined CRS/HIPEC than after prior CRS alone (17.2 months vs. 10.7 months, respectively; P = 0.52).ConclusionCytoreduction combined with HIPEC may improve loco‐regional disease control in patients with recurrent sarcomatosis. J. Surg. Oncol. 2013;107:329–334. © 2013 Wiley Periodicals, Inc.
Local and systemic exposure of cisplatin during hyperthermic intrathoracic chemotherapy perfusion after pleurectomy and decortication for treatment of pleural malignancies
Authors: Ried M. , Potzger T. , Braune N. , Diez C. , Neu R. , Sziklavari Z. , Schalke B. , Hofmann H.‐S. 
Published: February 2013

AbstractBackgroundAssessing the pharmacokinetics of intrapleurally administered cisplatin during hyperthermic intrathoracic chemotherapy perfusion (HITHOC) following pleurectomy/decortication in patients with malignant pleural mesothelioma or advanced thymoma with pleural spread.MethodsPharmacokinetic analysis (ICP‐MS) of intrapleural cisplatin with a dosage of 100 mg/m2 (n = 5) or 150 mg/m2 (n = 5) at 42°C perfusate temperature. Simultaneous pleural perfusion fluid and serum samples were collected at the beginning and every 15 min. Serum samples were collected at the end of the operation, 6, 12, and 24 hr postoperative.ResultsMean cisplatin levels in the perfusate slightly decreased during the HITHOC. The mean area under the curve ratios (AUCperfusate:AUCserum) of cisplatin were nearly similar. The mean AUCs of cisplatin in the perfusate were approximately 58 and 55 times greater than detected in the serum. The mean peak of cisplatin in the serum was reached after 1 hr of HITHOC. The AUC of cisplatin in the serum did not significantly differ (P = 0.18) between both groups up to 24 hr after perfusion.ConclusionsHITHOC with cisplatin provides a pharmacological advantage of high local intrapleural cisplatin concentrations. Elevation of the cisplatin dosage to 150 mg/m2 did not lead to a significant increase of the systemic cisplatin concentration. J. Surg. Oncol. 2013;107:735–740. © 2013 Wiley Periodicals, Inc.
RAFT Dispersion Polymerization of Styrene in Water/Alcohol: The Solvent Effect on Polymer Particle Growth during Polymer Chain Propagation
Authors: Huo Fei , Wang Xiaohui , Zhang Yaoyao , Zhang Xu , Xu Jianxiong , Zhang Wangqing 
Published: February 2013

AbstractThe RAFT polymerization of styrene in a solvent consisting of a water/alcohol mixture with different water contents is performed and the solvent effects on polymerization kinetics, polymer chain propagation, and polymer particle growth are evaluated. It is found that the solvent affects the RAFT polymerization kinetics greatly, and the apparent polymerization rate constant (Kp app) increases with an increase in the water content of the water/alcohol mixture. In addition, RAFT polymerization in a water/alcohol mixture with a higher water content affords better control of the polydispersity index (PDI) of the synthesized polymers. Furthermore, the solvent also exerts a great influence on the growth of the polymer particles. Hollow particles are formed either at the initial polymerization with low monomer conversion or in the solvent with a low water content, whereas solid polymer particles are produced either at high monomer conversion or in the solvent with a high water content.magnified image
Consumer‐Generated Representations: Muslim Women Recreating Western Luxury Fashion Brand Meaning through Consumption
Authors: Al‐Mutawa Fajer Saleh 
Published: February 2013

ABSTRACTThe aim of this paper is to explore the influence of consumer‐generated representations on symbolic brand meaning. The term consumer‐generated representation is used in this research to refer to the image created for a brand based on the defining characteristics of a consumer or group of consumers. A preliminary qualitative study consisting of 12 in‐depth interviews was conducted in Kuwait, specifically exploring Muslim female consumers as consumers of western luxury fashion brands. The findings show that Muslim female consumers generate “Modestly Sexy” representations that recreate meaning for western luxury fashion brands in Kuwait. Thus, marketers need to recognize the importance of managing consumer‐generated representations on a global scale.
Gadget Loving: A Test of an Integrative Model
Authors: Shoham Aviv , Pesämaa Ossi 
Published: February 2013

ABSTRACTFollowing the seminal work of Bruner and Kumar (2007) on gadget loving, this paper views gadget loving as the attachment individuals have toward advanced electronic items and how such an attachment relates to actual use (i.e., actual gadgets ownership). It extends existing research in two important ways. First, it provides a retest of the reliability and validity of the gadget‐loving scale in two new countries (Israel and Sweden), thus adding to the generalizability of the scale across cultures. Second, it develops and tests an integrative model that includes gadget loving as a central construct as well as several antecedents and consequences proposed as important topics for future research in the extant literature. The results show that inherent novelty seeking, technological innovativeness, and technical curiosity predict the gadget‐loving trait, which in turn affects technological opinion leadership and gadget ownership. These findings have theoretical and practical implications.
Third Party Customers Infecting Other Customers for Better or for Worse
Authors: Tombs Alastair G. , McColl‐Kennedy Janet R. 
Published: February 2013

ABSTRACTIn this article the effect of the displayed emotions of third party customers and purchase occasion on customers are examined, even when there is no direct interaction between customers. Three independent studies, including two experiments are employed. The first experiment examines the effects of both positive and negative displayed emotions of third party customers and purchase occasion on customer emotions and repurchase intentions, when there is no direct interaction between customers. The second experiment captures changes in the customers’ affective state on a moment‐by‐moment basis enabling differentiation between the effects of the service environment and the intervention of exposure to the displayed emotions of third party customers. Results show that customers are “infected” by the displayed emotions of third party customers even when there is no direct interaction between the customers. It is also demonstrated that the purchase occasion affects the type and intensity of emotions customers experience and the likelihood of repurchase. Implications for scholarly research and retailers are discussed.
Graph‐Based Consensus Clustering for Combining Multiple Clusterings of Chemical Structures
Authors: Saeed Faisal , Salim Naomie , Abdo Ammar , Hentabli Hamza 
Published: February 2013

AbstractConsensus clustering methods have been successfully used for combining multiple classifiers in many areas such as machine learning, applied statistics, pattern recognition and bioinformatics. In this paper, consensus clustering is used for combining the clusterings of chemical structures to enhance the ability of separating biologically active molecules from inactive ones in each cluster. Two graph‐based consensus clustering methods were examined. The Quality Partition Index method (QPI) was used to evaluate the clusterings and the results were compared to the Ward’s clustering method. Two homogeneous and heterogeneous subsets DS1–DS2 of MDL Drug Data Report database (MDDR) were used for experiments and represented by two 2D fingerprints. The results, obtained by a combination of multiple runs of an individual clustering and a single run of multiple individual clusterings, showed that graph‐based consensus clustering methods can improve the effectiveness of chemical structures clusterings.
Forchheimer and added mass effects in the flow towards a well
Authors: Nader José Jorge 
Published: February 2013

SUMMARYIn this note, we examine the flow towards a well in a confined aquifer in the presence of an interaction force defined by the sum of three terms, namely, a Darcy term (linear in the velocity), a Forchheimer term (quadratic in the velocity), and an added‐mass term (linear in the acceleration). We obtain the exact dynamic solution for the piezometric head distribution around the well and investigate the relative importance of the non‐Darcian terms. Copyright © 2013 John Wiley & Sons, Ltd.
Melanoma survivors at high risk of developing new primary disease: a qualitative examination of the factors that contribute to patient satisfaction with clinical care
Authors: McLoone J. K. , Watts K. J. , Menzies S. W. , Barlow‐Stewart K. , Mann G. J. , Kasparian N. A. 
Published: February 2013

AbstractBackgroundProviding ongoing clinical care that adequately addresses patients' medical, psychosocial and information needs is challenging, particularly for patient groups at increased risk of developing life‐threatening disease such as malignant melanoma. This study examined a model of clinical care developed by the High Risk Clinic (HRC) of the Sydney Melanoma Diagnostic Centre in relation to patient satisfaction.MethodsSemi‐structured telephone interviews were conducted and analyzed using the framework of Miles and Huberman, and themes were organized using the qualitative software package, QSR NVivo8.ResultsTwenty HRC patients participated in the study (nine men, 11 women; mean age 57.6 years, age range 34–74 years; response rate 91%). Satisfaction with clinical care at the HRC was high. Factors contributing to patient satisfaction included: rapid and regular access to physicians who were perceived by participants as experts, the development of confidence and trust in one's treating doctor, and a sense of being cared about and understood by one's healthcare team. Although one‐third of the participants reported some inconveniences in attending the clinic, these were viewed as minor difficulties and not significant barriers to care. Formal psychological support was not sought or expected by participants, although many expressed long‐standing melanoma‐related fears and concerns.ConclusionsAccessible, expert medical attention, delivered in a patient‐centered manner was integral to melanoma survivors' satisfaction with clinical management. Appropriate referrals to psychological support may further increase satisfaction with clinical care. Copyright © 2013 John Wiley & Sons, Ltd.
Dietary chlorantraniliprole suppresses reproduction in worker bumblebees
Authors: Smagghe Guy , Deknopper Janna , Meeus Ivan , Mommaerts Veerle 
Published: February 2013

AbstractBACKGROUNDPollinators such as the bumblebee, Bombus terrestris, fulfil a crucial role in agriculture. In this context, tests were conducted with the insecticide chlorantraniliprole (Coragen®) as a model compound active on the ryanodine receptor of insects.RESULTSChronic oral exposure via pollen induced lethargic behaviour in B. terrestris workers and their offspring (drones). Indeed, in nests exposed to 0.4 mg L−1, representing 1/100 of the concentration recommended for use in the field, workers and drones did not take their defensive position upon stimulation and they were less active than non‐exposed insects. The different risk assessment tests used here demonstrated that contact and pollen exposure had no effect on bumblebee worker survival, whereas oral exposure via sugar water caused both acute (72 h LC50 = 13 mg L−1) and chronic (7 week LC50 = 7 mg L−1) toxicity. Severe sublethal effects on reproduction were recorded in nests orally exposed to pollen treated with chlorantraniliprole.CONCLUSIONThe present study identified an important physiological endpoint of sublethal effects on reproduction, as this is associated with lethargic behaviour after oral intake. As such, this is a factor that should now be incorporated into future risk assessments. Secondly, it confirmed that the assessment of sublethal effects on behaviour is needed for adequate risk assessment of ‘potentially deleterious’ compounds with a neurogenic target, as is also pointed out in the recent European Food Safety Authority (EFSA) guidelines. © 2013 Society of Chemical Industry
Non‐target effects of herbicides on soil nematode assemblages
Authors: Zhao Jie , Neher Deborah A , Fu Shenglei , Li Zhi'an , Wang Kelin 
Published: February 2013

AbstractBackgroundHerbicides are used extensively to control weeds. However, little is known about the non‐target effects of herbicides on soil nematode assemblages. The objective of this study was to determine whether herbicides affect the abundance of nematodes in specific trophic groups. Meta‐analysis was performed, and the calculated effect size,lr, quantified the impact of herbicides on the abundance of total nematodes and five trophic groups (bacterivores, fungivores, plant parasites, omnivores and predators).ResultsMeasurements oflrindicated that herbicides decreased abundance of both fungivores and predators; however, abundance of bacterivores, plant parasites and omnivores increased. Overall, total nematode abundance tended to increase in response to herbicide application.ConclusionThe decrease in predator abundance suggests that herbicide application disturbs soil food webs. The increase in bacterivore and decrease in fungivore abundance suggest that bacterivores are more tolerant and both fungivores and predators more sensitive to herbicide applications. Herbicides also have non‐target effects on omnivores, which may be due to the increased amount of food resources for omnivores after weed control. Additionally, the use of herbicides may result in a risk of an increase in plant‐parasitic nematode abundance. © 2012 Society of Chemical Industry
RNA dot plots: an image representation for RNA secondary structure analysis and manipulations
Authors: Churkin Alexander , Barash Danny 
Published: February 2013

AbstractDot plots were originally introduced in bioinformatics as dot‐containing images used to compare biological sequences and identify regions of close similarity between them. In addition to similarity, dot plots were extended to possibly represent interactions between building blocks of biological sequences, where the dots can vary in size or color according to desired features. In this survey, we first review their use in representing an RNA secondary structure, which has mostly been applied for displaying the output secondary structures as a result of running RNA folding prediction algorithms. Such a result may often contain suboptimal solutions in addition to the optimal one, which can be easily incorporated in the dot plot. We then proceed from their passive use of providing RNA secondary structure snapshots to their active use of illustrating RNA secondary structure manipulations in beneficial ways. While comparison between RNA secondary structures can mostly be done efficiently using a string representation, there are notable advantages in using dot plots for analyzing the suboptimal solutions that convey important information about the structure of the RNA molecule. In addition, structure‐based alignment of dot plots has been advanced considerably and the filtering of dot plots that considers chemical and enzymatic data from structure determination experiments has been suggested. We discuss these procedures and how they can be enhanced in the future by using an image representation to analyze RNA secondary structures and examine their manipulations. WIREs RNA 2013, 4:205–216. doi: 10.1002/wrna.1154This article is categorized under:

RNA Evolution and Genomics > Computational Analyses of RNA
Using population genetics for management of bobcats in oregon
Authors: Reding Dawn M. , Carter Carolyn E. , Hiller Tim L. , Clark William R. 
Published: February 2013

AbstractIn Oregon, USA, bobcats on either side of the Cascade Mountain Range are recognized as distinct subspecies, with Lynx rufus fasciatus west and Lynx rufus pallescens east of the Cascades. These subspecies are currently managed for harvest as separate populations primarily because of substantial differences in regional pelt values. We used genetic data to determine whether bobcats in Oregon are subdivided into genetically discernible populations that support current regional management regulations. We collected 250 tissue samples from 12 a priori sampling districts, and generated data from 15 microsatellite markers and approximately 1 kB of mtDNA sequence. Results of clustering analyses based on the microsatellite data indicated strong support for the presence of 2 genetic populations, generally corresponding to the 2 subspecies. Analysis of molecular variance (AMOVA) indicated significant structure between the east and west regions, which accounted for 1.7% of the total variation in microsatellites. AMOVA based on the mtDNA sequences indicated significant structure between regions, accounting for 12.8% of the mtDNA variation. With both microsatellite and mtDNA data, we observed a significant pattern of isolation‐by‐distance, whereby geographically proximate sampling districts were more genetically similar than were more distant districts. We identified 21 putative migrants, individuals with genotypes more likely to have originated from the opposite region, showing that the Cascade Mountain Range apparently is not an absolute barrier to gene flow. Given the potential for differential harvest effort by region based on differences in pelt values and bobcat densities, and the vulnerability of bobcats to harvest, our results support the current management framework. © 2013 The Wildlife Society.
Anthropogenic impacts to the recovery of the Mexican gray wolf with a focus on trapping‐related incidents
Authors: Turnbull Trey T. , Cain James W. , Roemer Gary W. 
Published: February 2013

AbstractConcerns regarding the potential negative impacts of regulated furbearer trapping to reintroduced Mexican gray wolves (Canis lupus baileyi), led to an executive order prohibiting trapping in the New Mexico, USA, portion of the Blue Range Wolf Recovery Area. This ban was to last for 6 months and required an evaluation of the risk posed to wolves by traps and snares legally permitted in New Mexico. We reviewed potential threats to wolves in the Blue Range Wolf Recovery Area, including threats associated with regulated furbearer trapping. One hundred Mexican gray wolf mortalities have been documented during the reintroduction effort (1998–2011). Of those mortalities with a known cause, >81% were human‐caused resulting from illegal shooting (n = 43), vehicle collisions (n = 14), lethal removal by the United States Fish and Wildlife Service (USFWS; n = 12), non‐project‐related trapping (n = 2), project‐related trapping (n = 1), and legal shooting by the public (n = 1). Ten wolves died due to unknown causes. The remaining 17 mortalities were a result of natural causes (e.g., starvation, disease). An additional 23 wolves were permanently, but non‐lethally, removed from the wild by the USFWS. Of 13 trapping incidents in New Mexico that involved non‐project trappers (i.e., trappers not associated with USFWS or U.S. Department of Agriculture‐Wildlife Services), 7 incidents are known to have resulted in injuries to wolves: 2 wolves sustained injuries severe enough to result in leg amputations and 2 additional wolves died as a result of injuries sustained. Foothold traps with rubber‐padded jaws and properly set snares may reduce trap‐related injuries to Mexican gray wolves; however, impacts caused by trapping are overshadowed by other anthropogenic impacts (e.g., illegal shooting, non‐lethal permanent removal, and vehicle collisions). © 2013 The Wildlife Society.
Eliminative Behavior of Captive Numbats, Myrmecobius fasciatus (Mammalia; Marsupialia): Pattern and Identification of Fecal Deposits
Authors: Hogan Lindsay A. , Lisle Allan T. , Johnston Stephen D. 
Published: February 2013

AbstractThis study examined the spatial defecation patterns of numbats within captivity and tested the efficacy of a food colorant as a fecal marker in this species. Rather than randomly distributing scats throughout their environment, the numbats aggregated their feces at specific sites forming latrines. It is unclear whether the strong inclination for latrine formation was due to this species' inherent behavior or is a direct result of captivity. Males were found to have a higher daily defecation rate, different defecation time, larger number of latrines, and greater number of scats per quadrant, as compared to females. In this study, the majority of scats were deposited along enclosure boundaries and for both sexes there was a higher probability of latrines being placed along enclosure fencing shared with a female neighbor. The high concentration of latrines along boundaries suggests that they may play a role in territorial defense. The results also indicated that captive numbats tend to choose defecation points away from food and refuge sites. Transit and total retention time of the marker through the GIT was ≤3 hr and between 24 and 27 hr, respectively. A marker dose of 3 gtts feed−1 × 2 feeds day−1 was required to reach a steady and detectable state of marker output, which enabled accurate identification of individual samples during the breeding season. Reliable labeling was obtained using blue and red colored food dye, and there was no evidence that incorporation of the marker into the diet had any negative effects on food intake. Zoo Biol. 32:324–331, 2013. © 2013 Wiley Periodicals Inc.