bluuebunny/crossref_metadata_2025_split huggingface dataset:
The role of lipidic balance on erectile dysfunction in prostate cancer patients undergoing robotic surgery
Authors: Di Bello Francesco , Fraia Agostino , Pezone Gabriele , Collà Ruvolo Claudia , Di Mauro Ernesto , Cirillo Luigi , Fusco Giovanni Maria , Morra Simone , Aprea Salvatore , La Rocca Roberto , Califano Gianluigi , Creta Massimiliano , Longo Nicola , Napolitano Luigi 
Published: July 2024

ObjectiveNew indices of dyslipidemia, such as the Atherogenic Index of Plasma (AIP) or Castelli Risk Index I and II (CR‐I/II), have been tested to predict erectile dysfunction (ED). The aim of this study was to assess the role of these lipidic scores in predicting severe ED and erectile function (EF) worsening in patients who underwent robot‐assisted radical prostatectomy (RARP).MethodsData from 1249 prostate cancer patients who underwent RARP at our single tertiary academic referral center from September 2021 to April 2023 were reviewed. RARP patients with a complete lipid panel were included in the final analysis. Two independent multivariable logistic regression models (LRMs) were fitted to identify predictors of ED severity and worsening in RARP patients.ResultsAmong the 357 RARP patients, the median age was 70 (interquartile range [IQR]: 65–74), and the median BMI was 28.4 (IQR: 26–30.4). According to the preoperative IIEF5, 115 (32.2%), 86 (24.5%), 26 (7.3%), and 40 (11.2%) were mild, mild‐moderate, moderate, and severe ED patients, respectively. After multivariable LRMs predicting severe ED, only the nerve‐sparing (NS) approach (odds ratio [OR]: 0.09) as well as the preoperative IIEF5 score (OR: 0.32) were independent predictors (p < 0.001). After LRMs predicting EF worsening, only preoperative IIEF5 was an independent predictor (OR: 1.42, p < 0.001).ConclusionThe power of novel lipidic scores in predicting severe ED and EF worsening in RARP patients was low, and they should not be routinely applied as a screening method in this patient subgroup. Only preoperative IIEF5 and nerve‐sparing approaches are relevant in EF prediction after RARP.
Early coronary angiography in NSTEMI: a regional Victorian perspective
Authors: Ganes Anand , Henderson James , Samuel Rohit , Segan Louise , Hiew Chin , Hutchison Adam 
Published: July 2024

AbstractBackgroundCurrent guidelines highlight a paucity of evidence guiding optimal timing for non‐ST‐elevation myocardial infarction (NSTEMI) in high‐risk and non‐high‐risk cases.AimWe assessed long‐term major adverse cardiovascular events (MACEs) in NSTEMI patients undergoing early (<24 h) versus delayed (>24 h) coronary angiography at 6 years. Secondary end‐points included all‐cause mortality and cumulative MACE outcomes.MethodsBaseline characteristics and clinical outcomes were assessed among 355 patients presenting to a tertiary regional hospital between 2017 and 2018. Cox proportional hazard models were generated for MACE and all‐cause mortality outcomes, adjusting for the Global Registry of Acute Coronary Events (GRACE) score, patient demographics, biomarkers and comorbidities.ResultsTwo hundred and seventy patients were included; 147 (54.4%) and 123 (45.6%) underwent early and delayed coronary angiography respectively. Median time to coronary angiography was 13.3 and 45.4 h respectively. At 6 years, 103 patients (38.1%) experienced MACE; 41 in the early group and 62 in the delayed group (hazard ratio (HR) = 2.23; 95% confidence interval (CI) = 1.50–3.31). After multivariable adjustment, the delayed group had higher rates of MACE (HR = 1.79; 95% CI = 1.19–2.70), all‐cause mortality (HR = 2.76; 95% CI = 1.36–5.63) and cumulative MACE (incidence rate ratio = 1.54; 95% CI = 1.12–2.11). Subgroup analysis of MACE outcomes in rural and weekend NSTEMI presentations was not significant between early and delayed coronary angiography (HR = 1.49; 95% CI = 0.83–2.62).ConclusionHigher MACE rates in the delayed intervention group suggest further investigation is needed. Randomised control trials would be well suited to assess the role of early invasive intervention across all NSTEMI risk groups.
Sociopolitical ideologies as predictors of collective action across liberal and conservative domains: Injustice‐based anger, efficacy, and empathy as mediators
Authors: Choma Becky L. , Sumantry David , Nasser Leen 
Published: July 2024

AbstractSocial change can be spurred by collective action. Yet not all forms of collective action are in the name of social progress. People seeking to advance or oppose social progress can be ideologically driven to organize and push their agendas. In exploring psychological reasons for collective action, social scientists have focused mostly on social identity. Researchers have begun to study sociopolitical ideologies as another key motivator of collective action. Drawing on both collective action and sociopolitical ideology literatures, we investigate sociopolitical ideologies (right‐wing authoritarianism, social dominance orientation) as predictors of collective action across politically liberal (MeToo movement, Climate Change) and conservative (Anti‐Abortion, Illegal Immigration) domains. Results from two American samples (n = 681; n = 359) show that right‐wing ideologies relate to more collective action in politically conservative domains and less collective action in politically liberal domains. Between‐person differences in empathy, injustice‐based anger, and efficacy explain these associations.
Pulmonary vein reconnection and repeat ablation characteristics following cryoballoon‐compared to radiofrequency‐based pulmonary vein isolation
Authors: Obergassel J. , Nies M. , Taraba S. , Rottner L. , Lemoine M. D. , My I. , Moser F. , Rieß J. L. , Schenker N. , Dinshaw L. , Schleberger R. , Reißmann B. , Meyer C. , Willems S. , Rillig A. , Kirchhof P. , Metzner A. 
Published: July 2024

AbstractBackgroundDespite advances in efficacy and safety of pulmonary vein isolation (PVI), atrial fibrillation (AF) recurrence after PVI remains common. PV‐reconnection is the main finding during repeat PVI procedures performed to treat recurrent AF.ObjectiveTo analyze pulmonary vein (PV) reconnection patterns during repeat ablation procedures in a large cohort of consecutive patients undergoing radio frequency or cryoballoon‐based PVI.MethodsRetrospective analysis of PV‐reconnection patterns and analysis of re‐ablation strategies in consecutive index RF‐ and CB‐based PVI and their respective re‐ablation procedures during concomitant usage of both energy sources at a single high‐volume center in Germany.ResultsA total of 610 first (06/2015–10/2022) and 133 s (01/2016–11/2022) repeat ablation procedures after 363 (60%) RF‐ and 247 (40%) CB‐based index PVIs between 01/2015 and 12/2021 were analyzed. PV‐reconnection was found in 509/610 (83%) patients at first and 74/133 (56%) patients at second repeat procedure. 465 of 968 (48%) initially via CB isolated PVs were reconnected at first re‐ablation but 796 of 1422 initially RF‐isolated PV (56%) were reconnected (OR: 0.73 [95% CI: 0.62–0.86]; p < .001). This was driven by fewer reconnections of the left PVs (LSPV: OR: 0.60 [95% CI: 0.42–0.86]; p = .005 and LSPV: 0.67 [0.47–0.95]; p = .026). PV‐reconnection was more likely after longer, RF‐based index PVI and in older females. Repeat procedures were shorter after CB‐compared to after RF‐PVI.ConclusionsReconnection remains the most common reason for repeat AF ablation procedures after PVI. Our data suggest to preferentially use of the cryoballoon during index PVI, especially in older women.
LPS exacerbates TRPV4‐mediated itch through the intracellular TLR4‐PI3K signalling
Authors: Hao Yanping , Wu Liyan , Wang Yuhui , Shan Dongmei , Liu Yifei , Feng Jing , Chang Yi , Wang Ting 
Published: July 2024

AbstractPruritus is often accompanied with bacterial infections, but the underlying mechanism is not fully understood. Although previous studies revealed that lipopolysaccharides (LPS) could directly activate TRPV4 channel and TRPV4 is involved in the generation of both acute itch and chronic itch, whether and how LPS affects TRPV4‐mediated itch sensation remains unclear. Here, we showed that LPS‐mediated TRPV4 sensitization exacerbated GSK101‐induced scratching behaviour in mice. Moreover, this effect was compromised in TLR4‐knockout mice, suggesting LPS acted through a TLR4‐dependent mechanism. Mechanistically, LPS enhanced GSK101‐evoked calcium influx in mouse ear skin cells and HEK293T cells transfected with TRPV4. Further, LPS sensitized TRPV4 channel through the intracellular TLR4‐PI3K‐AKT signalling. In summary, our study found a modulatory role of LPS in TRPV4 function and highlighted the TLR4‐TRPV4 interaction in itch signal amplification.
Diversity, equity and inclusiveness in healthcare
Authors: Worman Scott 
Published: July 2024

AbstractAddressing Diversity, Equity and Inclusion in health care is a multidimensional challenge. From a US perspective, the third‐party payment system has disempowered and depersonalized health‐care delivery. The net result is wasteful and inefficient use of human and financial resources, burnout among providers, as well as care inequities. Financial integration at the point of patient care is essential to aligning the needs of patients with advances in medical technology. Complexity theory offers valuable insights into the roles of government, intermediaries and patients. The government must focus on equity as a rule compiler and referee of the system. Patient and providers who are actively engaged in shared decision‐making will naturally address the diverse needs of multitudinous communities. Intermediaries address inclusion by connecting resources with the point of care. In a dynamic, emerging health‐care system that serves diverse communities, patient and community‐based financing, vouchers and defined contributions are necessary first steps in addressing cultural diversity, inclusion and equity.
Emotion regulation in emotionally focused therapists working with high‐conflict couples
Authors: Yıldızhan Cemile , Kafescioğlu Nilüfer , Zeytinoğlu‐Saydam Senem , Erdem Gizem , Söylemez Yudum , Yumbul Çiğdem 
Published: July 2024

AbstractGuided by the Person‐of‐the Therapist Training (POTT) Model, the current qualitative study explores emotional experiences and emotion regulation strategies of emotionally focused trained therapists who work with high‐conflict couples in Turkey. Twenty‐one therapists who completed at least the externship in emotionally focused couple therapy (EFCT) and had prior or current clinical experience working with high‐conflict couple(s) were recruited through various social media platforms and professional organizations’ listservs. Semistructured individual interviews were conducted, audio‐recorded, and transcribed verbatim. Thematic analysis of the qualitative data revealed five main themes: (1) Different Compelling Emotional Experiences of the Therapists, (2) Sun After Storm, (3) Triggers of Therapists’ Emotions, (4) Perceived Adaptive Emotion Regulation Strategies, and (5) Positive Impact of the Therapist's Regulation Strategies on the Therapy Process. Overall, the findings supported the three phases of the POTT model: namely, knowledge of self, access to self, and use of self. Our study demonstrates the need for integrating self‐of‐the‐therapist work into the clinical practice, training, and supervision of therapists working with distressed couples.
Diagnostic yield of percutaneous, ultrasound‐guided, fine needle aspirates of the gastrointestinal wall: a retrospective analysis of 152 samples
Authors: Henry P. M. N. , Boag A. M. , Dandrieux J. R. S. , Rossi R. , Woods G. A. 
Published: July 2024

ObjectivesThe aim was to assess the technical success of percutaneous ultrasound‐guided fine needle aspirates of gastrointestinal wall lesions and evaluate predictors of success. Secondary aims included comparing the cytological diagnosis with histopathology, evaluating the utility of concurrent locoregional lymph node cytology and assessing the procedure's complication rate.Material and MethodsGastrointestinal wall cytology from 75 dogs and 70 cats obtained between 2018 and 2023 were reviewed and categorised as successful (resulting in a diagnostic cytology report) and accurate (resulting in the correct diagnosis when compared to histopathology). Unsuccessful fine needle aspirates, not submitted for cytology, were not recorded. Variables recorded included animal signalment, lesion and lymph node's appearance on ultrasound, size, location, number of smears submitted and experience of the ultrasonographer.ResultsOne hundred and fifty‐two reports were analysed. Eighty‐eight (58%) were successful: three normal epithelium, 21 inflammatory processes and 64 neoplasms. Variables associated with increased technical success included description of a mass, higher number of slides submitted and thickness of gastrointestinal lesion on ultrasound. Comparison with histopathology, performed for 17 lesions, showed discrepancies in eight, complete agreement in seven and partial in two. Eighty‐four loco‐regional lymph nodes were sampled, of which, 67 were successful (80%) and 52 brought additional clinical information (supporting GI wall cytology or diagnosing neoplasia not identified on GI wall cytology). No complication strictly attributable to gastrointestinal wall sampling was reported but when possibly related, death of the patient occurred in 2.5% of cases.Clinical SignificanceUltrasound‐guided fine needle aspirate of gastrointestinal wall had moderate accuracy and was unsuccessful in 42% of cases, but technical success increased when sampling mass lesions, thicker intestinal layers and submitting more slides.
Corpus Studies and ‘Close Listening’
Authors: MARTIN NATHAN JOHN 
Published: July 2024

ABSTRACTThis article provides a detailed response to Markus Neuwirth and Martin Rohrmeier's article ‘Wie wissenschaftlich muss Musiktheorie sein?’, published in the Zeitschrift der Gesellschaft für Musiktheorie in 2016. I undertake to nuance their call for the wholesale adoption of machine‐assisted corpus‐based methods in music theory through a detailed appreciation of work‐specific analysis as is has been practiced in American music theory. The argument unfolds through three case studies: of David Lewin's 1982 analysis of Schubert's ‘Auf dem Flusse’; of Vasili Byros's more recent approach to the Eroica Symphony; and then of Lewin again, on Schubert's ‘Morgengruß’. By means of these examples, I probe where corpus‐based methods can enhance traditional approaches and what new avenues of research they make possible, but I also emphasise those aspects of work‐specific analysis that elude their grasp.
The problematic but seductive call of prerogative power
Authors: Verbois Caleb 
Published: July 2024

AbstractThis article investigates and critiques the view that Lockean prerogative power is or should be incorporated, legally or extralegally, into the American constitutional system. Some scholars argue that extraconstitutional prerogative represents a safer alternative to a broad legal reading of presidential power, as it creates fewer precedents. Others suggest that the Framers “constitutionalized prerogative.” Both of these views have difficulties because ultimately, prerogative can create more dangerous precedents than legal uses of presidential power.
Upper‐flow‐regime deposits related to glacio‐volcanic interactions in Patagonia: Insights from the Pleistocene record in Southern Andes
Authors: Bucher Joaquín , del Papa Cecilia , Hernando Irene R. , Almada Gabriela 
Published: July 2024

AbstractSupercritical flows and their associated upper‐flow‐regime bedforms have been increasingly recognized in several contrasting depositional environments around the world, including volcano‐sedimentary settings. In recent years, there have been significant advances in flow modelling, architecture and depositional dynamics in upper‐flow‐regime bedforms related to glacio‐volcanic interaction, however most of these works come from specific volcanic landscapes. Examples of other regions with different tectonic and volcanic settings are needed in order to gain a more global perspective regarding the generation and preservation of upper‐flow‐regime glacio‐volcanic bedforms. This study presents a detailed analysis of Pleistocene volcaniclastic deposits accumulated in alluvial to lacustrine deltaic environments in the Southern Andes within the Southern Volcanic Zone. Six facies were defined and related to distinctive bedforms by examining sedimentary features, including textural characteristics, sedimentary structures, architecture and composition. Among these facies, five are distinguished by deposition from supercritical flows and upper‐flow‐regime bedforms, such as cyclic steps, chutes and pools, and antidunes. The stratigraphic succession reveals a predominance of repeated supercritical flows, which appear to be influenced by the availability of detritus for removal along with sudden water discharges. Compositional analyses indicate that explosive volcanism was the primary source of detritus, occurring synchronously with sedimentation. Additionally, the widespread occurrence of Pleistocene glacial conditions in this region suggests that volcanic‐induced melting ice or snow may have been an important source of water supply. Regarding the Southern Andes, the presence of local depressions, such as volcano‐tectonic calderas plays an essential role in the generation and preservation of the upper‐flow‐regime bedforms related to glacio‐volcanism. Furthermore, the importance of carrying out detailed and multidisciplinary studies seems to be critical for the recognition of these deposits in the record of the Andes.
Kurdish Women’s Experience in Iraq: History, Politics and Literature
Authors: Hassan Alhamid Lolav M. 
Published: July 2024

AbstractThe aim of this article is to study the conspicuous impact of the changing historical and political situation in Iraq on the Kurdish intellectual and literary production with particular attention to Kurdish women’s position and perspective on these changes. Focusing on the hectic periods of the Kurdish history and national movement in Iraq, the article answers such intriguing questions as how do the social and political discourses in Iraq shape Kurdish women’s roles and contributions and how has the interplay between Kurdish nationalism and women’s participation developed within the different literary, intellectual and political circles. Chronicling the various socio‐political dimensions of Kurdish national movement and investigating the ways in which Kurdish women’s participation has been relegated both by the Iraqi regimes and within the Kurdish national movements, the article presents a content analysis of different intentions, oversights, and insights of Kurdish and non‐Kurdish political, literary and intellectual actors regarding Kurdish women’s changing roles and desires in Iraq and of the images by which Kurdish women have been presented, thereby positioning itself within a socio‐political studies.
Using wearable sensors to explore schoolyard interactions of mainstreamed deaf and hard‐of‐hearing preadolescents
Authors: Eichengreen Adva , Tsou Yung‐Ting , van Klaveren Lisa‐Maria , Zaidman‐Zait Anat , Koutamanis Alexander 
Published: July 2024

AbstractSocial participation in school, including schoolyard interactions, is considered important for all aspects of child development. Students with disabilities, such as those who are deaf and hard‐of‐hearing, are at risk of experiencing inaccessibility and social exclusion in mainstream classes, yet this has been hardly researched in the schoolyard context. We exploratively compared preadolescents (M = 10.48, SD = .93) with (N = 8) and without (N = 207) hearing loss in their continuous schoolyard interactions during 21 recess assessments, using proximity sensors and field observations, alongside measurements of peer acceptance, friendships and sense of connectedness, based on peer nominations and self‐reports. Deaf and hard‐of‐hearing preadolescents spent less time interacting in the schoolyard, a trend which was stable throughout recess. Deaf and hard‐of‐hearing students interacted with the same number of partners as their classmates, but posthoc analyses suggest that towards the end of long recess periods they had a sharper drop in the number of their interaction partners. Field observations suggest that deaf and hard‐of‐hearing preadolescents who were socially active became more isolated the longer the break lasted, and that physical proximity did not necessarily indicate positive interactions. Findings underscore the importance of using multimethod designs that assess various dimensions of social participation and account for the temporal dynamics of recess interactions. Proximity sensors, combined with qualitative observations, enabled to detect social difficulties not detected by more traditional measures, hence valuable for social inclusion research and interventions.
Multiparametric myocardial mapping using cardiac magnetic resonance imaging in healthy dogs: Reproducibility, repeatability, and differences across slices, segments, and sequences
Authors: Yun Dain , Lee Hye‐Won , Jin Wooseok , Lee Kija , Lee Sang‐Kwon 
Published: July 2024

AbstractMyocardial mapping in humans has been widely studied and applied to understand heart disease, facilitate early diagnosis, and determine therapeutic targets; however, the reproducibility, repeatability, and protocol‐dependent differences in myocardial mapping in dogs remain unknown, which limits its application in dogs. This study investigated the reproducibility and test–retest repeatability of myocardial mapping in dogs and evaluated the differences according to slice, segment, and sequence. Precontrast T1 (native T1), T2 (T2), and T2* relaxation time (T2*), and extracellular volume (ECV) were measured at the base, midventricle, and apex of the left ventricle in six healthy beagles. To compare the sequences, the saturation recovery‐based (SMART1) and inversion recovery‐based (MOLLI) sequences were used for native T1 and ECV mapping. The intraclass correlation coefficient was measured to evaluate reproducibility and repeatability using the coefficient of variation and Bland‐Altman analysis. All parameters showed good to excellent intra‐ and interobserver reproducibility and test–retest repeatability. The apex slice showed the lowest repeatability among the slices, whereas ECV had the lowest repeatability among the parameters. Native T1, ECV, and T2* did not differ according to slice, but T2 significantly increased from the base to the apex. Native T1 was significantly higher in SMART1 than in MOLLI, whereas ECV did not differ between the two sequences. Our results suggest that myocardial mapping is applicable in dogs with high reproducibility and repeatability, although slice and sequence differences should be considered. This study can serve as a guide for myocardial mapping studies in dogs with heart disease.