bluuebunny/crossref_metadata_2025_split huggingface dataset:
The triple helix of environmental prosperity: Economic policy uncertainty, financial expansion, and green energy in a financially flourishing bloc
Authors: Naeem Fazale , Deng Yuping , Naveed Muhammad 
Published: August 2024

AbstractEcological impairments are considered one of the most contentious and uncertain subjects in intercontinental mediums, and they are also considered a significant apprehension for the entire world. Therefore, environmentalists and policymakers have turned their deliberation from conventional economic expansion to green economic growth. Even though existing studies have deliberated numerous determinants of environmental degradation, financial development, economic policy uncertainty, globalization, and renewable energy influence on ecological footprint is comparatively unexplored simultaneously, especially in financially developed economies. Hence, the present study explored the impact of financial development, economic policy uncertainty, globalization, and renewable energy on ecological footprint from 1995 to 2021. After confirming the issue of potential cross‐sectional dependency, this study employs a second‐generation econometric procedure to estimate robust and consistent estimates. The estimated results from augmented mean group (AMG) and common correlated effect mean group (CCEMG) estimators explored that financial development and renewable energy significantly protect the environment. Conversely, globalization and economic policy uncertainty increase the overall level of ecological footprint in the region. Based on these estimated results, the present research suggests some feasible policy insinuations for accomplishing targets of the Sustainable Development Goals (SDG‐7 and SDG‐13).
Human efferent ductules and epididymis display unique cell lineages with motile and primary cilia
Authors: Vinay Ludovic , Hess Rex A. , Belleannée Clémence 
Published: August 2024

AbstractBackgroundPrevious research has illustrated the role of cilia as mechanical and sensory antennae in various organs within the mammalian male reproductive system across different developmental stages. Despite their significance in both organ development and homeostasis, primary cilia in the human male reproductive excurrent duct have been overlooked due to limited access to human specimens.ObjectiveThis study aimed to characterize the unique cellular composition of human efferent and epididymal ducts, with a focus on their association with primary cilia.Materials and MethodsHuman efferent ductules/epididymides from five donors aged 32–47 years, were obtained through our local organ transplant program. Cell lineage specificity and primary cilia features were examined by immunofluorescent staining and confocal microscopy in the efferent ductules and the distinct segments of the epididymis.ResultsThe epithelium of the human efferent duct exhibited estrogen receptor‐positive cells with primary cilia, FoxJ1‐positive multiciliated cells with numerous motile cilia, and non‐ciliated intraepithelial immune cells. Notably, intraluminal macrophages, identified by CD163/CD68 positivity, were observed to engage in sperm phagocytosis. In all three segments of the human epididymis, primary cilia were found on the surface of principal and basal cells.Discussion and ConclusionsOur research indicates that the human efferent ductules create a distinct environment, characterized by the presence of two types of ciliated cells that are in contact with immune cells. The discovery of sensory primary cilia exposed on the surface of reabsorptive cells in the efferent ductules, as well as on basal and principal cells in the epididymis, lays the foundation for complementary functional studies. This research uncovers novel characteristics exclusive to human efferent ductules and epididymides, providing a basis for exploring innovative approaches to male contraception and infertility treatment.
Expression profiles and functional analysis of transfer RNA‐derived small RNAs (tsRNAs) in photoaged human dermal fibroblasts
Authors: Yao Amin , Zhang Yu , Ouyang Mengting , Wen Lei , Lai Wei 
Published: August 2024

AbstractTransfer RNA‐derived small RNAs (tsRNAs) refer to a newly established family of non‐coding RNAs that regulate a diverse set of biological processes. However, the function of tsRNAs in skin photoaging remains unclear. This research aims to investigate the potential correlation between tsRNAs and skin photoaging. Human dermal fibroblasts (HDFs) were irradiated with UVA at 10 J/cm2 once a day lasting for 14 days, resulting in the establishment of a photoaging model induced by UVA. To identify the expression profiles and functions of tsRNAs, tsRNA sequencing and bioinformatics analysis were conducted. qPCR was employed to validate the results of differentially expressed (DE) tsRNAs. A total of 34 tsRNAs exhibited significant differential expression between the UVA and control groups (n = 3), with nine upregulated and 25 downregulated (log2 fold change >1.5, p‐value <0.05). Six tsRNAs were selected at random and validated by qRT‐PCR. The enrichment analysis of DE tsRNAs target genes indicated that the dysregulated tsRNAs appeared to be connected with cell cycle, DNA replication and the AGE‐RAGE signaling pathway. The expression of tsRNAs was found to be aberrant in UVA‐HDF. These findings provide insights into the UVA‐induced damage and potential target genes for skin photoaging.
Les « noces parlementaires » : Rhétorique, Sémiotique et Droit. Convaincre dans une affaire de justice sociétale
Authors: Bertrand Denis 
Published: August 2024

Le contexte choisi est celui de l’ultime séance de débat à l'Assemblée nationale française le 23 avril 2013, avant le vote établissant dans le droit le « mariage pour tous » compris comme œuvre de justice sociétale. Cette nouvelle loi sera la réalisation majeure du gouvernement socialiste de l’époque. Alors même que le résultat du vote est acquis compte tenu de l’état des forces politiques et de la domination de la gauche, le débat préalable a lieu avec toute la force de ses arguments contradictoires. On analyse alors quelques courts extraits des discours prononcés à la tribune par des députés favorables ou opposés à cette loi, en nous interrogeant sur la pertinence d’un tel débat dont on sait que l’effet pragmatique sera nul. Cet épisode remarquable nous conduit à interroger les trois piliers de la rhétorique classique — les « genres » judiciaire, épidictique et délibératif — du point de vue sémiotique de la véridiction et sur l’horizon du discours juridique dans le rituel législatif fondateur du Droit. Ce discours, loin d’être exclusivement concerné par le genre judiciaire, se situe plutôt à la croisée de la célèbre tripartition générique. Entre vérité attestée (le judiciaire), vérité exaltée (l’épidictique) et vérité projetée (le délibératif), c’est dans l’entrelacs du pathémique que le discours du Droit construit ses modalités d’énonciation pour imposer ses énoncés normatifs et contribuer ainsi à l’édification du collectif. Notre hypothèse consiste alors à chercher dans ce syncrétisme générique la raison de la pertinence des prises de parole politico-juridiques « de circonstance » : leur visée, loin de l’effet pragmatique primaire d’un succès dans les urnes, serait de faire apparaître un « point de justesse » dont l’effet est de consolider le collectif et de contribuer à son institution à travers un rituel énonciatif qui semble à lui-même sa propre fin.
Multimodal and Multifactor Branching Time Active Inference
Authors: Champion Théophile , Grześ Marek , Bowman Howard 
Published: August 2024

Abstract
Active inference is a state-of-the-art framework for modeling the brain that explains a wide range of mechanisms. Recently, two versions of branching time active inference (BTAI) have been developed to handle the exponential (space and time) complexity class that occurs when computing the prior over all possible policies up to the time horizon. However, those two versions of BTAI still suffer from an exponential complexity class with regard to the number of observed and latent variables being modeled. We resolve this limitation by allowing each observation to have its own likelihood mapping and each latent variable to have its own transition mapping. The implicit mean field approximation was tested in terms of its efficiency and computational cost using a dSprites environment in which the metadata of the dSprites data set was used as input to the model. In this setting, earlier implementations of branching time active inference (namely, BTAIVMP and BTAIBF) underperformed in relation to the mean field approximation (BTAI3MF) in terms of performance and computational efficiency. Specifically, BTAIVMP was able to solve 96.9% of the task in 5.1 seconds, and BTAIBF was able to solve 98.6% of the task in 17.5 seconds. Our new approach outperformed both of its predecessors by solving the task completely (100%) in only 2.559 seconds.
Sex determination through maxillary dental arch and skeletal base measurements using machine learning
Authors: de Araujo Cristiano Miranda , de Jesus Freitas Pedro Felipe , Ferraz Aline Xavier , Quadras Isabella Christina Costa , Zeigelboim Bianca Simone , Priolo Filho Sidnei , Beisel-Memmert Svenja , Schroder Angela Graciela Deliga , Camargo Elisa Souza , Küchler Erika Calvano 
Published: August 2024

Abstract
Background
Cranial, facial, nasal, and maxillary widths have been shown to be significantly affected by the individual’s sex. The present study aims to use measurements of dental arch and maxillary skeletal base to determine sex, employing supervised machine learning.

Materials and methods
Maxillary and mandibular tomographic examinations from 100 patients were analyzed to investigate the inter-premolar width, inter-molar width, maxillary width, inter-pterygoid width, nasal cavity width, nostril width, and maxillary length, obtained through Cone Beam Computed Tomography scans. The following machine learning algorithms were used to build the predictive models: Logistic Regression, Gradient Boosting Classifier, K-Nearest Neighbors (KNN), Support Vector Machine (SVM), Multi-Layer Perceptron Classifier (MLP), Decision Tree, and Random Forest Classifier. A 10-fold cross-validation approach was adopted to validate each model. Metrics such as area under the curve (AUC), accuracy, recall, precision, and F1 Score were calculated for each model, and Receiver Operating Characteristic (ROC) curves were constructed.

Results
Univariate analysis showed statistical significance (p < 0.10) for all skeletal and dental variables. Nostril width showed greater importance in two models, while Inter-molar width stood out among dental measurements. The models achieved accuracy values ranging from 0.75 to 0.85 on the test data. Logistic Regression, Random Forest, Decision Tree, and SVM models had the highest AUC values, with SVM showing the smallest disparity between cross-validation and test data for accuracy metrics.

Conclusion
Transverse dental arch and maxillary skeletal base measurements exhibited strong predictive capability, achieving high accuracy with machine learning methods. Among the evaluated models, the SVM algorithm exhibited the best performance. This indicates potential usefulness in forensic sex determination.
Risk of nosocomial coronavirus disease 2019: comparison between single- and multiple-occupancy rooms
Authors: Jo Hyeon Jae , Choe Pyoeng Gyun , Kim Ji Seon , Lee Mimi , Lee Minkyeong , Bae Jiyeon , Lee Chan Mi , Kang Chang Kyung , Park Wan Beom , Kim Nam Joong 
Published: August 2024

Abstract
Background
There is an ongoing controversy regarding whether single-occupancy rooms are superior to multiple-occupancy rooms in terms of infection prevention. We investigated whether treatment in a multiple-occupancy room is associated with an increased incidence of nosocomial coronavirus disease 2019 (COVID-19) compared with treatment in a single-occupancy room.

Methods
In this retrospective cohort study, every hospitalization period of adult patients aged ≥ 18 years at a tertiary hospital in Korea from January 1, 2022, to December 31, 2022, was analyzed. If COVID-19 was diagnosed more than 5 days after hospitalization, the case was classified as nosocomial. We estimated the association between the number of patients per room and the risk of nosocomial COVID-19 using a Cox proportional hazards regression model.

Results
In total, 25,143 hospitalizations per room type were analyzed. The incidence rate of nosocomial COVID-19 increased according to the number of patients per room; it ranged from 3.05 to 38.64 cases per 10,000 patient-days between single- and 6-bed rooms, respectively. Additionally, the hazard ratios of nosocomial COVID-19 showed an increasing trend according to the number of patients per room, ranging from 0.14 (95% confidence interval 0.001–1.03) to 2.66 (95% confidence interval 1.60–4.85) between single- and 6-bed rooms, respectively.

Conclusions
We demonstrated that the incidence of nosocomial COVID-19 increased according to the number of patients per room. To reduce nosocomial infections by respiratory viruses, the use of multiple-occupancy rooms should be minimized.
Potential endocrine-disrupting effects of iprodione via estrogen and androgen receptors: evaluation using in vitro assay and an in silico model
Authors: Yang Ji-Yeon , Lim Jeong-Hyun , Park Soo-Jin , Jo Youmi , Yang Si Young , Paik Min-Kyoung , Hong So-Hye 
Published: August 2024

AbstractThis study was conducted to provide evidence, using in vitro and in silico testing methods, regarding the adverse effects of iprodione, a representative dichlorophenyl dicarboxamide fungicide, on the endocrine system. In the present study, we used the HeLa9903 stably transfected transactivation assay (OECD TG 455), 22Rv1/MMTV_GR‒KO androgen receptor transcriptional activation assay (OECD TG 458), and toxicity prediction using VEGA QSAR. Our results showed that iprodione had no estrogen receptor antagonistic or androgen receptor agonistic effects; however, iprodione was determined to be an estrogen receptor agonist (log PC10 value is less than − 9) and androgen receptor antagonist (log IC30 value is − 4.58) without intrinsic toxicity against the human cell lines used in this study. VEGA QSAR was used to evaluate five substances with structures similar to that of iprodione. Among them, four chemicals were found to have positive androgen receptor and aromatase activities and have been observed to be developmental toxicants. These results suggest that iprodione regulates steroid hormone receptor interactions and is a potential reproductive toxicant.
Laparoscopic resection of a descending colon tumor with right-sided fixation of the sigmoid colon: a case report
Authors: Ohno Shinya , Nagata Yukimasa , Kawahara Tatsuki , Nonomura Yusuke , Tachikawa Reo , Shinoda Tomohito , Tawada Kakeru , Ikawa Aiko , Sano Bun 
Published: August 2024

Abstract
Background
Intestinal malrotation is a condition in which the process of counterclockwise rotation and fixation to the peritoneum and retroperitoneum during fetal life is incomplete. In adults, it is generally asymptomatic and is often discovered incidentally. We report a case of laparoscopic partial resection of the descending colon for a tumor of the descending colon with a rare form of intestinal malrotation in which the inferior mesenteric artery ran symmetrically and the sigmoid colon was fixed to the dorsal cecum and right-sided retroperitoneum.

Case presentation
A 75-year-old man was referred to our department of internal medicine due to a positive fecal occult blood test. Lower endoscopy revealed a laterally spreading tumor in the descending colon, and endoscopic submucosal dissection was attempted; however, this procedure was difficult, and the patient was referred to our department for surgical treatment. Contrast-enhanced computed tomography revealed that the endoscopic clip was located in the descending colon on the right side, the inferior mesenteric artery was symmetrical, and the sigmoid colon was located on both the right and dorsal sides of the cecum. Laparoscopic ileocecum and sigmoid colon mobilization was performed from the left side of the patient. After the completion of sigmoid colon mobilization, which returned the sigmoid colon and descending colon to anatomical normalcy, laparoscopic partial resection of the descending colon was performed. Based on the results of a histopathological examination, a granular type of laterally spreading tumor was diagnosed. The patient was discharged uneventfully on postoperative day 8.

Conclusions
Detailed preoperative imaging and surgical simulation are necessary for abdominal surgery involving intestinal malrotation.
Identification of maize seed vigor based on hyperspectral imaging and deep learning
Authors: Xu Peng , Fu Lixia , Pan Yongfei , Chen Dongquan , Yang Songmei , Yang Ranbing 
Published: August 2024

Abstract
Background
Seed vigor identification is critical to guaranteeing the quality and yield of maize. Although seeds with impaired vigor may germinate under normal conditions, planting under unfavorable conditions makes it difficult to produce healthy plants. Therefore, non-destructive and rapid detection of seed vigor using hyperspectral imaging (HSI) technology is crucial for improving crop production efficiency.

Methods
Hyperspectral images of maize seeds were acquired employing the HSI system, the original spectra were preprocessed using Savitzky–Golay smoothing and multiplicative scatter correction, and the feature wavelengths were extracted using the successive projections algorithm (SPA). Discriminant models were constructed based on support vector machine (SVM), random forest, artificial neural network (ANN), and convolutional neural network (CNN-DC).

Results
The results showed that SVM, ANN, and CNN-DC could discriminate well between maize seeds with different vigor levels, and their accuracy rate was over 70%. The SPA algorithm showed that the RMSE value achieved a minimum of 0.3406, while the number of variables was 49. The CNN-DC model outperformed the other models, which reached the highest accuracy of 92.06%. This study demonstrates that DL combined with HSI has excellent potential for identifying seed vigor.

Conclusions
This study shows that the proposed method has excellent results for hyperspectral image data processing and can accurately identify maize seed vigor.
Increased Traumatic Brain Injury Severity and Mortality in Undocumented Immigrants
Authors: Tenorio Alexander , Brandel Michael G. , McCann Carson P. , Real Marcos , Doucet Jay J. , Costantini Todd W. , Santiago-Dieppa David R. , Levy Michael , Ciacci Joseph D. 
Published: August 2024

BACKGROUND AND OBJECTIVES:
Health disparities related to traumatic brain injury (TBI) have focused on socioeconomic status, race, and ethnicity. We sought to characterize TBI patterns and outcomes based on undocumented status.

METHODS:
Patients who presented to University of California, San Diego Health Trauma Center with a TBI between 2019 and 2022 were identified and stratified based on undocumented status. Undocumented immigrants were identified using validated methods of absent or invalid social security number and key terms through chart review. Demographic information, injury characteristics, and neurosurgical interventions were recorded. Univariable and multivariable analyses were performed to determine the impact of patient factors on outcomes.

RESULTS:
Of 1654 patients with TBI, 76 (4.6%) were undocumented. Undocumented immigrants were younger (50 vs 60 years; P < .001) and had higher Injury Severity Score (17 vs 13; P < .001). They presented from farther distances (12.8 vs 5.3 miles, P < .001) with greater midline shift (1.49 vs 0.91 mm; P = .003). A greater proportion had basal cistern compression/effacement (14% vs 4.6%; P = .001) and required neurosurgical intervention (18% vs 9.6%; P = .012). Undocumented immigrants had higher hospital charges ($208 403 vs $128 948; P < .001), length of stay (5 vs 4 days; P = .002), and were discharged to a health facility at a lower rate (18% vs 32%; P = .012). They had nearly double the mortality rate (14% vs 7.3%; P = .021), with undocumented status trending as a predictor on multivariable regression (odds ratio = 2.87; P = .052).

CONCLUSION:
Undocumented immigrants presented from farther distances with increased TBI severity, likely from both more severe trauma and delayed presentation, requiring more neurosurgical intervention. They also had greater length of stay, charges, and nearly double the mortality rate. Importantly, undocumented status was a strong predictor for mortality. Despite worse outcomes, they were discharged to a health care facility at a lower rate. Advocacy efforts should be directed at increasing health care coverage and migrant community engagement and education.
Identifikasi Potensi Bahaya Kerja pada Instalasi Catatan Medik RSUP Dr Sardjito Yogyakarta
Authors: Probo Marisa Kuncaraning , Mudayana Ahmad Ahid 
Published: August 2024

Rumah sakit memiliki ancaman besar terhadap dampak kesehatan bagi pekerja, pasien dan pengunjung. Berdasarkan studi pendahuluan, Instalasi Catatan Medik (ICM) RSUP Dr. Sardjito Yogyakarta memiliki 162 pegawai dan berbagai jenis pekerjaan yang memiliki potensi bahaya tersendiri. Di bagian penyimpanan berkas misalnya, memiliki potensi bahaya debu, kegiatan angkat-angkut berkas, dan lain-lain. Sehingga perlu dilakukan penelitian dengan tujuan mengetahui potensi bahaya kerja pada ICM RSUP Dr Sardjito Yogyakarta. Penelitian ini berjenis deskriptif kualitatif melalui observasi lapangan, wawancara, dan telaah dokumen. Penelitian ini melibatkan enam narasumber dan analisa data menggunakan lembar kerja Job Safety Analysis (JSA). Diketahui ada 13 jenis pekerjaan yang ada di ICM RSUP Dr. Sardjito Yogyakarta, yaitu: registrasi, filing, distribusi, verifikasi, coding, assembling, penggabungan, surat keterangan medis, penelitian, pelaporan, penyusutan, pemusnahan, dan logistik. Setiap jenis pekerjaan tersebut terbagi menjadi beberapa langkah aktivitas yang memiliki potensi bahaya yang berasal dari: radiasi monitor, sekeliling kertas dan isi stapler yang tajam, debu; alat kerja dumbwaiter, stapler, gunting, dan Roll O’ Pack; kegiatan angkat-angkut, posisi kerja, lokasi kerja yang tinggi, cara dan lama bekerja; kegiatan berulang, komunikasi dengan pasien/ keluarga, serta dengan petugas/pihak lain, dan beban kerja yang tidak tentu; dari aliran listrik; dan bakteri/ virus dari berkas, maupun dari pasien sendiri saat kontak langsung. Upaya pengendalian risiko yang telah ditetapkan di ICM RSUP Dr Sardjito Yogyakarta mengikuti hirarki pengendalian risiko, yaitu: substitusi, rekayasa teknik, administrasi, dan alat pelindung diri. Sedangkan upaya eliminasi yang disarankan sedang dalam proses, menunggu optimalisasi pemberlakuan Elektronik Medical Record. Telah diketahui berbagai potensi bahaya kerja pada ICM RSUP Dr Sardjito Yogyakarta hingga dapat diberlakukan pengendalian risiko sesuai hirarki pengendalian risiko.