bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Synergistic Anti-tumor Effects of Evodiamine based on Animal Model
Experiments: A Systematic Review and Meta-analysis
Authors: Zheng He , Lv Siyi , Lin Liqi , Li Rongrong , Li Lin , Pang Yunqing , Wang Jing 
Published: July 2024

Background:
Evodiamine (EVO) is an alkaloid extracted from the dried and nearly
ripe fruits of Euodia rutaecarpa and used as an anti-cancer, anti-inflammatory and anti-obesity
agent. However, robust evidence of preclinical experiments has been lacking so far. Therefore, the
purpose of this article was to investigate the effect of EVO in combination with other treatments
on tumors in animal experiments.

Methods:
A systematic review and meta-analysis were conducted to assess the anti-tumor effect
of evodiamine-combined therapy. The search engine and electronic databases included PubMed,
Scopus, China Knowledge Resource Integrated Database (CNKI), and SinoMed. The research
method was based on the PRISMA checklist.

Results:
A total of 7 studies and 108 animals were included. As a result, EVO combined therapy
was found to be more effective than EVO monotherapy. The SMD was -25.64(95% CI: -5.77
-3.13) in tumor growth. In tumor weight, the SMD was -8.91(95% CI: -16.37, -1.44).

Conclusion:
EVO has the potential to alleviate the toxicity of chemotherapeutic agents, which increases the translatability to the clinical situation.
Synchronized Glioma Insights: Trends, Blood Group Correlations, Staging Dynamics, and the Vanguard of Liquid Biopsy Advancements
Authors: Sheikh Ryan Adnan , Naqvi Salma , Al-Sulami Ayman Mohammed , Bayamin Mohammed , Samsahan Abdullaha , Baig Mirza Rafi , Al-Abbasi Fahad A. , Almalki Naif A.R. , Asar Turky Omar , Anwar Firoz 
Published: July 2024

Background:
Gliomas are the most frequent, heterogeneous group of tumors arising from
glial cells, characterized by difficult monitoring, poor prognosis, and fatality. Tissue biopsy is an established
procedure for tumor cell sampling that aids diagnosis, tumor grading, and prediction of
prognosis.

Materials and Methods:
We studied and compared the levels of liquid biopsy markers in patients
with different grades of glioma. Also, we tried to prove the potential association between glioma
and specific blood group antigens.

Results:
78 patients were found, among whom the maximum percentage with glioblastoma had
blood group O+ (53.8%). The second highest frequency had blood group A+ (20.4%), followed by
B+ (9.0%) and A- (5.1%), and the least with O-. Liquid biopsy biomarkers included Alanine Aminotransferase
(ALT), Lactate Dehydrogenase (LDH), lymphocytes, Urea, Alkaline phosphatase
(AST), Neutrophils, and C-Reactive Protein (CRP). The levels of all the components increased significantly
with the severity of the glioma, with maximum levels seen in glioblastoma (grade IV),
followed by grade III and grade II, respectively.

Conclusion:
Gliomas have significant clinical challenges due to their progression with heterogeneous
nature and aggressive behavior. A liquid biopsy is a non-invasive approach that aids in setting
up the status of the patient and figuring out the tumor grade; therefore, it may show diagnostic and
prognostic utility. Additionally, our study provides evidence to prove the role of ABO blood group
antigens in the development of glioma. However, future clinical research on liquid biopsy will improve
the sensitivity and specificity of these tests and confirm their clinical usefulness to guide
treatment approaches.
Research and Application of a Generalized Power Communication Framework with Joint Security Protection Mechanism
Authors: Xiao Qiyuan , Yu Jiawen , Wang Jie , Zhuang Yufei , Zhu Qiang 
Published: July 2024

Background:
The rapid development of Industry 4.0 has opened up new power systems,
which face a more complex network topology and a broader range of security threats. This
has led to an urgent demand for a coordinated, lightweight, and secure communication management
method.

Methods:
This paper presents a general power communication framework with a joint security
protection mechanism that is suitable for coordinated management and transmission safety. The
framework manages the protocol’s thread management of the device by converting it to the
framework’s process management. It formulates specifications for protocols and equipment that
access the framework to achieve support for multiple protocols and equipment. This reduces the
difficulty of system operation and maintenance, as well as system complexity, and improves
management efficiency. Additionally, the joint security protective mechanism for plugin authentication
and protocol encryption is introduced to enable secure data transmission and guarantee
the framework's security management. Finally, two experiments have been conducted to discuss
and confirm the effectiveness and safety of the framework.

Results:
The results of the two experiments and the following analysis show that our framework is
superior to the chosen well-known industrial commercial communication platforms, and the time
delay cost by our mechanism doesn’t significantly affect the real-time data transmission in the
power industry, proving its feasibility in both IoT and power applications.

Conclusion:
Our framework demonstrates exceptional performance in terms of time lag and packet
loss during the experiment, surpassing other IoT communication frameworks. Furthermore, it
maintains its high standards even under rigorous security analysis.
Pengaruh Tata Letak Tanam Pada Berbagai Varietas Kubis Bunga (Brassica oleracea var. botrytis L.)
Authors: Girsang Srimayanti , Suryanto Agus 
Published: July 2024

Tanaman kubis bunga (Brassica oleracea var.botrytis L.) merupakan salah satu komoditas pertanian dengan permintaan pasar yang cukup tingi karena memiliki banyak manfaat serta vitamin dan mineral. Penelitian bertujuan untuk mengetahui jenis varietas dan penggunaan tata letak tanam yang lebih baik terhadap pertumbuhan dan hasil produksi tanaman kubis bunga. Penelitian dilaksanakan bulan Maret sampai dengan Juni 2023 di lahan percobaan Fakultas Pertanian, Universitas Brawijaya, terletak di kelurahan Jatimulyo, Kecamatan Lowokwaru, Kota Malang. Penelitian ini disusun dengan Rancangan Acak Kelompok (RAK) dengan 3 macam varietas dan 2 tata letak tanam sehingga terdapat 6 kombinasi perlakuan dengan 4 ulangan yaitu: P1: Varietas Orient + Bujur sangkar, P2: Varietas Orient + Zig-zag, P3: Varietas PM 126 + Bujur sangkar, P4: Varietas PM 126 + Zig-zag, P5: Varietas Bima + Bujur sangkar, P6: Varietas Bima + Zig-zag. Pengamatan dilakukan pada parameter pertumbuhan dan parameter panen tanaman. Pengamatan pertumbuhan dilakukan secara destruktif dan non destruktif, sedangkan pengamatan hasil dilakukan pada saat pemanenan. Hasil penelitian menunjukan bahwa Varietas Orient, PM 126 dan Bima dengan tata letak tanam bujur sangkar dibandingkan dengan varietas Bima dengan tata letak tanam zig-zag memperoleh panjang tanaman yang sama dan relatif lebih panjang, Varietas Orient dan PM 126 dengan tata letak tanam bujur sangkar dan zig-zag memperoleh hasil daun yang relatif lebih besar dari pada varietas Bima dengan tata letak tanam zig-zag. Varietas Orient, PM 126 dan terutama Bima dengan berbagai perlakuan tata letak tanam memberikan hasil per tanaman dan per hektar yang sama yaitu berkisar antara 239,38-253,4 g/tanaman dan 17.95-19.00 ton.ha-1.
Sharing knowledge without borders: Collaboration between U.S. business and law students and Spanish translation students
Authors: López-Arroyo Belén , Pizarro-Sánchez Isabel , Moreno-Pérez Leticia 
Published: July 2024

Collaboration between technical and professional (TP) writers in English as a second language is important for successful communication. This is evident in legal documents in both English and Spanish, where accuracy and clarity are paramount. However, achieving this is challenging because law students often lack effective writing tools, and translation students may lack the required encyclopedic knowledge. The present paper describes a co-designed exchange project between U.S. students in business and law and students of legal translation at a university in Spain. This paper aims to determine potential improvements in students’ encyclopedic and conceptual knowledge of this specialized language and their translation performance after the collaboration intervention. To evaluate these aspects, three textual items were targeted: terminological, nominal and, what we call, substitutional density. Our results indicate that peer collaboration helped Spanish students acquire encyclopedic knowledge in the field and avoid repetitive terms in their translations, leading to greater textual cohesion through the use of general language, synonyms and hypernyms. Other aspects of this peer collaboration as well as follow-up approaches to consolidate the observed effects are needed.
Parenting-Related Social Networking Site Use and Psychological Distress in Parents of Infants: Cross-sectional Study Exploring the Moderating Effects of Loneliness and Parenting Anxiety
Authors: Onishi Ryuta 
Published: July 2024

Abstract

Background
In the digital age, social networking sites (SNSs) have revolutionized the approach to parenting. These platforms, widely used to access parenting information and support, affect parents both positively and negatively, with negative effects potentially increasing for those experiencing loneliness or anxiety.

Objective
This study examined the relationship between SNS use and psychological distress among parents of young children, controlling for the moderating effects of loneliness and parenting anxiety. We hypothesized that higher SNS use correlates to greater psychological distress, particularly among parents with elevated levels of loneliness or parenting anxiety.

Methods
A cross-sectional survey design using a closed web-based questionnaire was employed. Participants included 429 parents (205 mothers and 224 fathers) of children aged 0‐3 years recruited through a web-based survey company in Japan. The majority of the participants were couples, with some living with extended family members. The sample also encompassed individuals in cohabiting partnerships and single parents. The survey included measures of psychological distress, loneliness, parenting anxiety, frequency of SNS use for parenting, and covariates. Analytical models to explain psychological distress included interactions between loneliness or parenting anxiety and SNS use, individually for both fathers and mothers.

Results
For mothers, a significant interaction effect was determined only between parenting anxiety and SNS use (b=0.247, SE 0.091; P=.008). Meanwhile, for fathers, significant interaction effects were observed for both loneliness (b=0.324, SE 0.127; P=.012) and parenting anxiety (b=0.144, SE 0.069; P=.038) with SNS use. A simple slope analysis for mothers indicated that SNS use was related to psychological distress only at higher levels of parenting anxiety (b=0.304, SE 0.090, β=.317; P<.001). Among fathers, SNS use was associated with psychological distress at higher levels of either parenting anxiety (b=0.330, SE 0.069, β=.346; P<.001) or loneliness (b=0.390, SE 0.098, β=.409; P<.001).

Conclusions
The study concluded that the relationship between SNS use and psychological distress among parents of young children is moderated by loneliness and parenting anxiety. The findings highlight the need for tailored approaches to help parents manage SNS use, particularly focusing on those with higher levels of loneliness and parenting anxiety. It is imperative that health professionals provide nuanced guidance to parents on SNS use, considering individual psychological factors and potential gender differences in the impact of SNSs on mental well-being.
Oil Recovery From Spent Bleaching Earth With Reflux Extraction Method Using Acetonitrile and n-Hexane Solvent
Authors: Maryudi Maryudi , Rahayu Aster , Suharto Totok Eka , Hakika Dhias Cahya , Zufar Ahmad Fatwa 
Published: July 2024

Abstract: The growth of the oleochemical industry generated a large amount of spent bleaching earth (SBE) solid waste that causes environmental problems. The SBE solid waste produced is reported at about 600,000 metric tons per year. Recovery of the oil from SBE can be an alternative solution to reduce the negative impact of SBE solid waste. In this study, the recovery of oil from SBE was carried out by the reflux extraction method followed by a study on its properties. The oil recovery process was conducted by using two different solvents (acetonitrile and n-hexane) at different particle sizes (40, 60, 100 mesh) of SBE, solvent-SBE ratios (2:1, 3:1, 4:1), and extraction time (1, 2, 3 hours). Experimental results showed that n-hexane extracted oil with yield ranged from 5 to 14.8%, while acetonitrile extracted oil with yield ranged from 0.68 to 8.4%. Product analysis shows that the oil extracted has a water content of 1.56% and 2.53% for acetonitrile and n-hexane, respectively. The viscosity analysis results show that the oil viscosities were 5.83 cSt (acetonitrile) and 5.09 cSt (n-hexane) which is in reasonable agreement with the Indonesian National Standard for vegetable oil (SNI 7709:2019). The result suggested that n-hexane provided better product yield than acetonitrile as a solvent for oil recovery from SBE. This study provides an alternative method and solution for the oleochemical industry in managing SBE waste.Abstrak : Pertumbuhan industri oleokimia menghasilkan limbah padat berupa tanah pemucat (spent bleaching earth/ SBE) yang mengakibatkan permasalahan lingkungan. Limbah padat SBE yang dihasilakn dilaporkan sekitar 600.000 ton per tahun. Pemisahan minyak dari SBE dapat menjadi alternatif penyelesaian masalah untuk menurunkan dampak negatif dari limbah SBE. Dalam penelitian ini, recovery minyak dari SBE dilakukan dengan metode ekstraksi reflux dan dilanjutkan karakterisasi hasil minyak. Recovery minyak dilakukan dengan dua jenis pelarut (asetonitril and n-heksana) dengan ukuran partikel SBE bervariasi (40, 60, 100 mesh), perbandingan pelarut-SBE (2:1, 3:1, 4:1), dan waktu ekstraksi (1, 2, 3 jam). Hasil penelitian menunjukkan bahwa asetonitril mengekstrak minyak dengan yield 1,56-2,53%, sementara n-heksana berkisar 5-14,8%. Minyak hasil ekstraksi menunjukkan kadar air 1.56% (asetonitril) and 2.53% (n-heksana), serta nilai viskositas sebesar 5.83 cSt (asetonitril) and 5.09 cSt (n-heksana). Minyak hasil memenuhi SNI Minyak goreng sawit (SNI 7709:2019). Hasil menunjukkan n-heksana memiliki kemampuan lebih baik dibanding asetonitril dalam mengekstrak minyak dari SBE. Hasil penelitian memberikan penyelesaian alternatif dalam menagngani limbah SBE dari industri oleokimia.
The Influence of Tilt Angle of 120 WP Solar Panels on Light Intensity and Generated Electrical Power
Authors: Masthura Masthura , Daulay Abdul Halim 
Published: July 2024

Abstract: In designing solar panel devices, generally the tilt angle of the panel surface is designed with a static design and this greatly influences the results of the electricity source generated. The design of the tool is intended to be in coordinates that are perpendicular to the direction of the sunlight rays so that it receives maximum solar radiation. This research aims to determine the relationship between the tilt angle of the solar panels and the light intensity and electrical power generated and to determine the optimal tilt angle of the solar panels based on the values of light intensity and electrical power. The indicators measured consist of light intensity, voltage, current and electrical power by varying the tilt angle of the solar panel. The results of this research show that the tilt angle of the solar panel greatly influences the measured light intensity value so that the greater the light intensity obtained, the higher the output voltage of the solar panel. The most optimal tilt angle is at an angle of 105o and 120o with the greatest light intensity so that the resulting output power is correspondingly greater.Abstrak: Dalam merancang alat panel surya, pada umumnya posisi kemiringan dari permukaan panel dirancang dengan desain statis sangat mempengaruhi hasil dari sumber listrik yang dihasilkan. Rancangan alat diupayakan berada di koordinat yang tegak lurus dengan arah pancaran cahaya matahari agar menerima radiasi matahari yang maksimal. Penelitian ini bertujuan untuk mengetahui hubungan posisi kemiringan panel surya terhadap intensitas cahaya dan daya listrik yang dihasilkan serta mengetahui posisi kemiringan panel surya yang optimal berdasarkan nilai intensitas cahaya dan daya listriknya. Indikator yang diukur terdiri dari intensitas cahaya, tegangan, arus, dan daya listrik dengan memvariasikan posisi kemiringan dari panel surya. Hasil penelitian ini menunjukkan posisi kemiringan sebuah panel surya sangat mempengaruhi nilai intensitas cahaya yang diukur sehingga semakin besar intensitas cahaya yang didapat maka tegangan keluaran panel surya mengalami kenaikan. Posisi kemiringan yang paling optimal pada sudut 105o dan 120o dengan intensitas cahaya yang didapat terbesar sehingga daya keluaran yang dihasilkan sejalan yaitu semakin besar pula.
Иррациональность как составная часть стратегии трансгрессии и ее потенциал в совладании с неопределенностью
Authors: Sapogova Elena Evgenyevna 
Published: July 2024

The author presents a theoretical and methodological analysis of the phenomenon of irrationality and examines its potential in the process of coping with the discomfort of uncertainty. In the paradigm of existential psychology, irrationality is presented as one of the ways of resisting uncertainty, the increasing obsolescence of individual experience in the conditions of growing awareness of the uncertainty of existence, the immaturity of modern people, and the danger of developing a fragmented identity. The article presents the idea that turning to irrationality in the process of coping with uncertainty acts as an integral part of the strategy of transgression, which can not only take the subject beyond the framework of rational cognition of reality but also provide him with new experiences of adaptation to an uncertain existence and access to the level of new possibilities or logical comprehension of reality and self-understanding (axiology, Bayesian logic, imaginative logic, logic of synchronicity). The author compares the possibilities of rational and irrational thinking and behavior in situations of uncertainty when the available experience is not sufficient, and a person who cares for himself cannot avoid making decisions and acting. The work formulates provisions on irrationality and transgression as components of the mechanisms of meaning formation and self-development.
Автором представлен теоретико-методологический анализ феномена иррациональности, рассмотрены его возможности в процессах совладания с переживанием дискомфорта неопределенности. В парадигме экзистенциальной психологии иррациональность представлена как один из возможных способов противостояния прекарности, ускоряющемуся устареванию индивидуального опыта в условиях нарастающего осознания неопределенности существования, невзросления современных людей и рисков становления фрагментарной идентичности. В статье аргументируется идея, что в процессах совладания с неопределенностью обращение к иррациональности выступает как составляющая часть стратегии трансгрессии, способной не просто вывести субъекта за рамки рационального познания реальности, но и дать ему новый опыт адаптации к прекарному существованию и обеспечить выход в плоскость новых возможных «логик» осмысления реальности и самого себя (аксиологики, бейесовой логики, имажинативной логики, логики синхронистичности). Автор сопоставляет возможности рационального и иррационального мышления и поведения в ситуациях неопределенности, когда имеющегося опыта оказывается недостаточно, а избежать необходимости принятия решения и действования человек, осуществляющий «заботу о себе», не может. В работе формулируются положения об иррациональности и трансгрессии как составных частях механизмов смыслообразования и саморазвития.
Determinants of the Human Development Index (Case Study of 12 Districts in East Java)
Authors: Putri Amalia Elena , Susilowati Dwi 
Published: July 2024

All countries face human development problems. As indicated by the relatively low level of the HDI. The quality of human life is an important factor in the development process. Of the 38 cities/districts in East Java, 12 districts require attention because they are categorized as moderate HDI levels by 2022. Therefore, it is important to make efforts to improve the quality of human development during the development process. This study aims to examine the independent socio-economic variables of poverty, economic growth, sanitation, and clean water on the dependent variable, namely the human development index in 12 districts of East Java Province in 2015-2022. This research uses panel data with the best model selection, namely the fixed effect model, and the test criteria are set at an error rate of 5%. The analysis results in an Adj R-Square value of 93.79%, which indicates a strong correlation between variables. The remaining 6.21% can be attributed to other factors not included in the analysis. Specifically, the results of this study explain the variables that affect and do not affect the human development index.
Infections Connected with Organ and Tissue Transplantation
Authors: Laudy Agnieszka E. , Tyski Stefan 
Published: July 2024

Abstract
Transplantology is a branch of medicine that is developing rapidly. Transplanted whole organs or segments of organs may be recovered from either living or deceased donors. New methods of preserving transplanted solid organs, including the kidney, liver, heart, lung, and pancreas, as well as tissues, such as the cornea and skin, are being developed. Preservation fluid, which is used to perfuse and store the donated organ or tissue, should reduce biological deterioration of organs and tissue, attenuate ischemia/reperfusion-induced cell/tissue injury, and protect against damage. Lowering the storage temperature of organs significantly reduces the risk of damage. Efforts are also made to shorten the time between collecting the organ or tissue from the donor and transplanting it in the recipient. However, during transplantation, the recipient may become infected, primarily with bacteria and fungi. Infections of organ recipients occur most often due to unhygienic organ collection, improper handling and transport, and inappropriate preservation conditions, especially contamination of preservation fluid. The literature on contamination of organ preservation fluid and infections in graft recipients is very diverse, both in terms of the isolated bacterial and fungal species and the number of incidents. A large percentage of contaminating microorganisms belong to the generally non-pathogenic skin microbiota, but there are also cases of multidrug-resistant bacteria. Besides, the transplanted organs themselves may pose a danger. They may contain latent microorganisms, mainly viruses and parasites, that could be activated in a patient who has been subjected to immunosuppression to reduce the risk of organ rejection.