bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tahapan pembelajaran ilmu pengetahuan sosial berdiferensiasi berbasis Asset Based Community Development (ABCD)
Authors: Lewu Ezra Gerry Yohanes 
Published: August 2024

Model pembelajaran berdiferensiasi menjadi salah satu strategi yang ditawarkan dalam pelaksanaan kurikulum merdeka. Setiap guru diarahkan untuk melihat berbagai potensi siswa dan lingkungan sekitar agar dapat dimanfaatkan untuk memenuhi capaian pembelajaran. Pendekatan Asset Based Community Development (ABCD) dapat menjadi salah satu pilihan dalam melaksanakan pembelajaran berdiferensiasi khususnya dalam Pelajaran Ilmu Pengetahuan Sosial (IPS). ABCD dapat dimanfaatkan sebagai kerangka konseptual untuk membangun pembelajaran yang berbasis pada kekuatan lokal yang dimiliki oleh setiap komunitas belajar. Melalui analisis studi literatur dan refleksi pembelajaran, penelitian ini mengidentifikasi tahapan-tahapan yang dapat dilakukan untuk melaksanakan pembelajaran IPS berdiferensiasi dengan berbasis aset lokal. Tahapan tersebut mencakup Pemetaan Aset, Membangun Ikatan dan Hubungan, Mobilisasi Komunitas, Penemuan dan Imajinasi, Evaluasi dan Refleksi serta Dukungan Eksternal. Penelitian ini menggambarkan bagaimana model ABCD dapat diintegrasikan dalam praktik pembelajaran kurikulum merdeka. Tahapan-tahapan ini diharapkan dapat menjadi alternatif dalam pelaksanaan praktik pembelajaran berdiferensiasi yang responsif terhadap keberagaman murid dan aset lokal yang dimiliki. Kata kunci: pembelajaran berdiferensiasi, pengembangan komunitas berbasis aset, ilmu sosial
Achievement of safer learning facilities standards in the disaster safe education unit program at Panggang elementary school
Authors: Utami Anindita Ayu Nisa , Dwiastuti Anggit Nur , Nurmalasari Yuli 
Published: August 2024

This study aims to discover and describe the achievement of safer learning facility standards for the disaster safe education unit program at Panggang elementary school, Bambanglipuro. This study is a descriptive evaluative research mixed methods approach with a sequential explanatory strategy. The sampling technique was carried out with saturated samples. Data collection techniques used observation, interviews, documentation studies, and questionnaires. Data validity uses internal validation, technical triangulation, and source triangulation. Quantitative data analysis uses a percentage formula calculation according to Sugiyono, while qualitative data analysis uses an interactive analysis model. However, each aspect still has gaps. The gaps that occur are not too significant, but still affect the achievement of safer learning facilities. Efforts are needed from Panggang elementary school Bambanglipuro to reduce or even eliminate existing gaps so that safe learning facilities in the disaster safe education unit program can be fully achieved. Keywords: program evaluation, disaster safe education unit program, safer learning facilities
Mitigating Sociodemographic Bias in Opioid Use Disorder Prediction: Fairness-Aware Machine Learning Framework
Authors: Yaseliani Mohammad , Noor-E-Alam Md , Hasan Md Mahmudul 
Published: August 2024

Background
Opioid use disorder (OUD) is a critical public health crisis in the United States, affecting >5.5 million Americans in 2021. Machine learning has been used to predict patient risk of incident OUD. However, little is known about the fairness and bias of these predictive models.

Objective
The aims of this study are two-fold: (1) to develop a machine learning bias mitigation algorithm for sociodemographic features and (2) to develop a fairness-aware weighted majority voting (WMV) classifier for OUD prediction.

Methods
We used the 2020 National Survey on Drug and Health data to develop a neural network (NN) model using stochastic gradient descent (SGD; NN-SGD) and an NN model using Adam (NN-Adam) optimizers and evaluated sociodemographic bias by comparing the area under the curve values. A bias mitigation algorithm, based on equality of odds, was implemented to minimize disparities in specificity and recall. Finally, a WMV classifier was developed for fairness-aware prediction of OUD. To further analyze bias detection and mitigation, we did a 1-N matching of OUD to non-OUD cases, controlling for socioeconomic variables, and evaluated the performance of the proposed bias mitigation algorithm and WMV classifier.

Results
Our bias mitigation algorithm substantially reduced bias with NN-SGD, by 21.66% for sex, 1.48% for race, and 21.04% for income, and with NN-Adam by 16.96% for sex, 8.87% for marital status, 8.45% for working condition, and 41.62% for race. The fairness-aware WMV classifier achieved a recall of 85.37% and 92.68% and an accuracy of 58.85% and 90.21% using NN-SGD and NN-Adam, respectively. The results after matching also indicated remarkable bias reduction with NN-SGD and NN-Adam, respectively, as follows: sex (0.14% vs 0.97%), marital status (12.95% vs 10.33%), working condition (14.79% vs 15.33%), race (60.13% vs 41.71%), and income (0.35% vs 2.21%). Moreover, the fairness-aware WMV classifier achieved high performance with a recall of 100% and 85.37% and an accuracy of 73.20% and 89.38% using NN-SGD and NN-Adam, respectively.

Conclusions
The application of the proposed bias mitigation algorithm shows promise in reducing sociodemographic bias, with the WMV classifier confirming bias reduction and high performance in OUD prediction.
The Effect of Prebedtime Behaviors on Sleep Duration and Quality in Children: Protocol for a Randomized Crossover Trial
Authors: Jackson Rosie , Gu Chao , Haszard Jillian , Meredith-Jones Kim , Galland Barbara , Camp Justine , Brown Deirdre , Taylor Rachael 
Published: August 2024

Background
It is recommended that children should avoid eating dinner, being physically active, or using screens in the hour before bed to ensure good sleep health. However, the evidence base behind these guidelines is weak and limited to cross-sectional studies using questionnaires.

Objective
The aim of this randomized crossover trial was to use objective measures to experimentally determine whether recommendations to improve sleep by banning electronic media, physical activity, or food intake in the hour before bed, impact sleep quantity and quality in the youth.

Methods
After a baseline week to assess usual behavior, 72 children (10-14.9 years old) will be randomized to four conditions, which are (1) avoid all 3 behaviors, (2) use screens for at least 30 minutes, (3) be physically active for at least 30 minutes, and (4) eat a large meal, during the hour before bed on days 5 to 7 of weeks 2 to 5. Families can choose which days of the week they undertake the intervention, but they must be the same days for each intervention week. Guidance on how to undertake each intervention will be provided. Interventions will only be undertaken during the school term to avoid known changes in sleep during school holidays. Intervention adherence and shuteye latency (time from getting into bed until attempting sleep) will be measured by wearable and stationary PatrolEyes video cameras (StuntCams). Sleep (total sleep time, sleep onset, and wake after sleep onset) will be measured using actigraphy (baseline, days 5 to 7 of each intervention week). Mixed effects regression models with a random effect for participants will be used to estimate mean differences (95% CI) for conditions 2 to 4 compared with condition 1.

Results
Recruitment started in March 2024, and is anticipated to finish in April 2025. Following data analysis, we expect that results will be available later in 2026.

Conclusions
Using objective measures, we will be able to establish if causal relationships exist between prebedtime behaviors and sleep in children. Such information is critical to ensure appropriate and achievable sleep guidelines.

Trial Registration
Australian New Zealand Clinical Trials Registry ACTRN12624000206527; https://tinyurl.com/3kcjmfnj

International Registered Report Identifier (IRRID)
DERR1-10.2196/63692
Evaluation of In-vitro Antioxidant and Antimutagenic Effect of Annona squamosa Leaves Extract
Authors: Dwivedi Shourya , Khan Kajal , Jain Surendra 
Published: August 2024

Green medicine, the drugs derived from plants attained a wide spread interest, as believed to be safe and dependable, compared with costly synthetic drugs that have adverse effects. In this study, Annona Squamosa (A. squamosa) have been investigated for their phytochemical, antioxidant, antimutagenic activities. Qualitative analysis of various phytochemical constituents and quantitative analysis of total phenol were determined by the well-known test protocol available in the literature. The extraction yield was found in the order: methanol>water>ethyl acetate>hexane. The extracts found to possess saponin glycosides, cardiac glycosides, phenolics, terpenoids, sterols, and flavonoids. The total phenolic content of hexane, ethyl acetate, methanolic and aqueous extract of A. squamosa were 3.04±0.37, 5.83±0.29, 31.42±2.35, and 27.21±1.06 GAE mg/g, respectively. The methanolic extracts exhibited highest amount of total polyphenol content compared to all other solvent extracts. The ethyl acetate, methanolic and aqueous extracts were evaluated for their antioxidant potential in terms of DPPH radical scavenging capabilities. The scavenging was found to dose dependent with IC50 value of 185.24, 103.09 and 160.17 µg/ml for the ethyl acetate, methanol and aqueous extracts respectively. The antimutagenic potential of the methanolic extract was studied using Ames test using T98 strain of Salmonella typhimurium applying NPD as the mutagen. The number of reverant colonies were counted using a digital colony counter and the reduction in colonies was calculated as the activity (%) of the extract at four doses. The reverent colonies were visible as lawn like structures on the surface of the plate and were significantly lower compared to positive control in the extract plate and the negative control. The extract was able to control the growth of reverant colonies upto 79.30% in comparison to the mutagenic control. The results show that the methanolic extract of A. squamosa leaf was able to exhibit a dose regulated antimutagenic activity by inhibiting the growth of His+ reverant colonies of Salmonella typhimurium.
Keywords: Green medicine, Annona Squamosa, Phytochemical, Antioxidant, Antimutagenic activities, Salmonella typhimurium
Review on Nanogel as a Novel Platform for Smart Drug Delivery System
Authors: Mendake Rupali A. , Hatwar Pooja Ramdas , Bakal Ravindrakumar L. , Amalkar Shriyog V. 
Published: August 2024

One of the most popular applications of nanotechnology in both topical and internal medicine administration to the body is nanogel technology. The materials comprising the nanoparticulate frameworks are less than 100 nm in a single measurement. The goal of this review paper is to provide a concise overview of the most recent developments in the nanogel medicine delivery framework with regard to drug loading and swelling. It categorises according to links (chemical and physical) and responding behaviour. This article is to give a broad overview of nanogels, their innovative use in many contexts, and current synthesis techniques. NGs use drugs for a variety of reasons, including diagnostics, gene targeting, organ targeting, and many more. Different pulmonary, nasal, transdermal, intra-ocular, oral, and parenteral routes can be used to give NGs. The primary goals of this review are to present broad details on NGs, their characteristics, multiple categories, medication targeting strategies, kinds of drug delivery systems, assessment techniques, and cutting-edge uses for NGs in depth.
Keywords: Nanogel, DLS, CD, mechanism of drug release, classification, application
Magnitude of anemia and associated factors among adults with tuberculosis in Galkaio Public Health Facilities Puntland, Somalia 2024: A cross-sectional study design
Authors: Ahmed Mohyadin Abdullahi , Diriye Abdulahi Said , Ali Mustafe Abdi , Yusuf Beder Jama 
Published: August 2024

Background: Treatment of anemia associated with TB may involve addressing the underlying cause, such as improving nutrition or managing inflammation, and sometimes may require blood transfusions.
Objective: The objective of this study is to assess the magnitude of anemia and associated factors among adults with tuberculosis in Galkaio town Public Health Facilities Puntland, Somalia 2024.
Methods: A facility-based cross-sectional study was used. A total sample of 422 adults with tuberculosis include in this study. Attending Health facilities in Galkaio town. Systematic random sampling technique was used to select the study participants. Structured questionnaires were used to obtain information related to socio-demographic characteristics. Data from both questioner and laboratory were checked and cleaned for completeness and consistency. Data was entered into Epi data version 3.1 and was analyzed using Statistical Package for the Social Science (SPSS) Version 20 statistical software. Both bivariate with cut off < 0.25 and multivariate with cut off < 0.05 analysis has been used to check the strength of association between dependent and independent variables.
Result: The overall magnitude of anemia was 82.7% CI :( 78.09, 86.31).In multivariable logistic regression analyses, the odds of anemia were 4.23 times higher for patients aged between 41-50 years [AOR=4.23, 95% CI (1.92,9.34)] compared to those aged between 18-30 years, 6.12 times higher for patients unable to read and write compared to those who had a college diploma and above [AOR=6.12, 95% CI (2.63,14.2)], and 5.71 times higher for patients who had not started taking Anti-TB drugs compared to those who had started [AOR=5.71, 95% CI (2.68,12.14)].
Conclusion: the magnitude of anemia among adults with tuberculosis in the study area was found to be high (82.7%). The study revealed that age, gender, occupation, TB treatment status, started taking Anti-TB drugs, and BMI as key factors associated with anemia. These findings underscore the importance of targeted interventions and healthcare strategies for at-risk individuals, with the aim of reducing the burden of anemia.
Analysis of Antioxidant Effects of Quercetin, Rutin and Phagnalon Rupestre on Rats Intoxicated by Aluminium
Authors: Yiga Henry Junior , Samuel Mulondo 
Published: August 2024

Aluminium (Al) is one of the most abundant chemical elements in nature and metal in the earth’s crust. Accumulation of Aluminium ions (Al3+) in target tissues results into formation of oxygen radicals causing oxidative damage through inducing cytotoxicity. The aim of this study is to analyse the antioxidant effect of selected polyphenols (quercetin, rutin and a medicinal plant phagnalon rupestre) on rats intoxicated by aluminium with specific focus on the heart.This experiment was carried out on 6 groups of wistar albino rats ,group 1; positive control, group 2; Al male intoxicated group treated with quercetin, group 3; Al male intoxicated group treated with rutin, group 4; Al female intoxicated, group 5; Al intoxicated treated with phagnalon rupestre , group 6; female control. Several Biochemical assays were carried out such as protein test, Thiobarbituric acid reactive substance (TBARS) assay, catalase assay (CAT), glutathione-s-transferase (GST) assay, superoxide dismutase (SOD) assay, Glutathione reduced and glutathione peroxidase (GSH & GPX) assay, lipids (cholesterol & triglycerides) assays. Aluminium intoxicated group showed decrease in the content of protein compared to the control and treated groups. Aluminium intoxicated group showed an increase in the activity of thiobarbituric reactive substances (TBARS) but a significant decrease in the activity of catalase (CAT), glutathione S transferase assays (GST) compared to the control group. Biomarkers of oxidative stress significantly reduced in heart Al-induced oxidative stress by administration of Quercetin. Therefore, Quercetin is an effective antioxidant against oxidative stress caused by free radicals produced because of aluminium exposure.
Keywords: antioxidant ;aluminium ; quercetin ; rutin ; phagnalon rupestre
A Study on Prevalence of Hypertension Among Patients Attending OPD of National Institute of Unani Medicine, Bengaluru, India.
Authors: Mir Uzair Yousf , Parveen Shaik Adeena , Abbasi Safia , Nayab Mohd , Ansari Abdul Nasir 
Published: August 2024

Introduction: Hypertension is the leading modifiable cause of premature death and hence World Health Organization (WHO) has made it one of its global prevention priorities. It is a major risk factor for stroke, myocardial infarction, vascular disease, and chronic kidney disease. The prevention and treatment of hypertension imposes a significant public health challenge owing to its related morbidity and mortality as well as the expense to society. Hypertension is referred to as a silent and an invisible killer and affects at least 1.4 billion people globally. Less than half of adults (42%) with hypertension are diagnosed and treated.
Methodology The research design was an institution based single centered, observational descriptive study, cross sectional in design and was carried out for a duration of 28 days (4 weeks) from 01.06.2024 to 29.06.2024. The study was conducted in the Outpatient Department (OPD) of Regimenal therapies, National Institute of Unani Medicine (NIUM), Bengaluru. All people above 21 years of age attending OPD constituted study population. In present study, 524 patients were included in the study. The diagnosis of hypertension was done as per WHO guidelines. Data analysis was done using SPSS version 24.
Results: The study revealed that prevalence of hypertension was 35.87% in the study population. In the present study, 53.20% of diagnosed hypertensive patients were females and rest 46.80% were males. Majority of diagnosed hypertensive patients (39.89%) belonged to the age group of above 60 years.
Conclusion: Prevalence of hypertension is significantly increasing at a greater pace globally as well as in India. Periodic screening and raising awareness about hypertension in general population is necessary to reduce the prevalence of the disease and thereby the associated morbidity and mortality.
Keywords: Hypertension, WHO, Prevalence, SPSS, OPD patients.
An efficient bentonite clay catalyzed multicomponent synthesis of substituted spirooxindoles in water/ethanol solvent system
Authors: Bajpai Shivam , Bhatia Sunil , Bajpai Anil Kumar , Asthana Sarvesh Narain 
Published: August 2024

The present report demonstrates an efficient use of bentonite clay to bring about multicomponent synthesis of substituted spirooxindoles 4a-h in Water/ ethanol solvent system under the mild reaction conditions.
Keywords: Bentonite clay, multicomponent synthesis, spirooxindoles
EDUKASI TENTANG PENGETAHUAN, SIKAP DAN PERILAKU MASYARAKAT TERHADAP PENCEGAHAN DEMAM BERDARAH DENGUE (DBD)
Authors: Salikunna Nur Asmar , Rahma Badaruddin  , Muh. Zainul Ramadhan  , Vera Diana Towidjojo  , Adi Widhiastu  
Published: August 2024

Dengue hemorrhagic fever (DHF) is a disease caused by the dengue virus with Aedes aegypti as the main vector. Diseases (DHF) can cause death and cases tend to fluctuate from year to year in Indonesia, including Palu City. Therefore, we carry out community service for the prevention of DHF in Palu City. As for the activities that we carried out in the form of distributing questionnaires, educating the community around the final waste disposal site in the Kawatuna village. The education we provide is the eradication of mosquito nests through the application of 3M Plus, including draining water reservoirs, closing water reservoirs, recycling used goods that can potentially become mosquito breeding grounds. In addition to education, we also provide mosquito repellent lotion for use during the day.The service that we have done can make the community around the final waste disposal site aware of the importance of preventing dengue fever and can be seen from the enthusiasm of relevant stakeholders and the local community.
Edukasi Kesehatan Reproduksi Pada Remaja di SMAN 5 Palu
Authors: Diana Towidjojo Vera , Sari Puspita , Asrinawaty Andi Nur 
Published: August 2024

Adolescents need an understanding of reproductive health to reduce and avoid the dangers of reproductive health disorders. This activity aims to increase the knowledge of young women about reproductive health. The method was a learning model to increase understanding of reproductive health. Participants were 100 students of SMAN 5 Palu who were randomly selected. Most of the students have good knowledge and understanding of reproductive health and use various sources to obtain information on reproductive health.
Kajian Teknologi Farmasi untuk Menghasilkan Produk Pangan Fungsional di Desa Tosale, Kabupaten Donggala
Authors: Sultan Asriana , Yusriadi Yusriadi , Syamsidi Armini , Sulistiana Sri , Sulastri Evi , Sharon Nela 
Published: August 2024

Pangan fungsional saat ini merupakan pangan yang perkembangannya maju pesat di dunia, seiring dengan semakin tingginya permintaan dan kesadaran masyarakat tentang kesehatan. Berbagai produk pangan fungsional dapat dihasilkan dengan melimpahnya sumber komponen bioaktif baik pada hasil panen pertanian, tanaman herbal, produk pangan hewani (susu), dan mikroorganisme non-patogen (Lactobacillus) yang dapat meningkatkan kesehatan karena dapat berefek sebagai antioksidan, antiradang, antidiabetes, dan lain sebagainya. Teknologi farmasi merupakan salah satu ilmu yang dapat diterapkan untuk menghasilkan produk pangan fungsional yang berkualitas. Oleh karena itu, kegiatan pengabdian masyarakat ini dilaksanakan untuk memperkenalkan teknologi farmasi khususnya teknik pengawetan bahan pangan kepada masyarakat desa Tosale agar dapat mengolah hasil pertanian menjadi produk pangan fungsional yang berkualitas dan memiliki nilai ekonomis yang lebih tinggi. Metode yang digunakan dalam kegiatan ini yaitu melalui edukasi atau penyuluhan. Tahapan penyuluhan dalam kegiatan ini yaitu pemaparan materi melalui materi presentasi, booklet dan video edukasi untuk menyampaikan informasi yang dibutuhkan untuk meningkatkan pemahaman masyarakat Desa Tosale terhadap edukasi yang telah diberikan. Kegiatan ini dapat meningkatkan pengetahuan masyarakat Desa Tosale tentang pangan fungsional, manfaatnya dalam peningkatan kesehatan dan pencegahan penyakit serta cara menghasilkan produk pangan fungsional yang berkualitas. Hasil yang telah diperoleh dari pelaksanaan kegiatan pengabdian kepada masyarakat ini berupa luaran kegiatan dalam bentuk booklet yang berisi informasi mengenai jenis-jenis teknik pengawetan dan metode pengawetan bahan pangan yang telah dibagikan kepada masyarakat saat penyuluhan. Booklet ini menjadi media informasi yang dapat diterapkan oleh masyarakat setempat untuk mencoba membuat produk pangan dari hasil perkebunan di Desa Tosale untuk dikonsumsi sendiri maupun dijadikan usaha rumah tangga. Selain itu, hasil pelatihan berupa peningkatan pengetahuan peserta pelatihan diukur melalui nilai rata- rata pre-test yaitu sebesar 70,77 dibandingkan dengan nilai rata-rata post-test yaitu 94,62. Hasil ini menunjukkan adanya peningkatan persentasi nilai sebesar 23,85%.