bluuebunny/crossref_metadata_2025_split huggingface dataset:
Individual and organizational factors related to work engagement among home‐visiting nurses in Japan
Authors: Naruse Takashi , Sakai Mahiro , Watai Izumi , Taguchi Atsuko , Kuwahara Yuki , Nagata Satoko , Murashima Sachiyo 
Published: January 2013

AbstractAimThe increasing number of elderly people has caused increased demand for home‐visiting nurses. Nursing managers should develop healthy workplaces in order to grow their workforce. This study investigated the work engagement of home‐visiting nurses as an index of workplace health. The aim of the present study was to reveal factors contributing to work engagement among Japanese home‐visiting nurses.MethodsAn anonymous, self‐administered questionnaire was sent to 208 home‐visiting nurses from 28 nursing agencies in three districts; 177 (85.1%) returned the questionnaires. The Job Demands–Resources model, which explains the relationship between work environment and employee well‐being, was used as a conceptual guide. The authors employed three survey instruments: (i) questions on individual variables; (ii) questions on organizational variables; and (iii) the Utrecht Work Engagement Scale (Japanese version). Multiple regression analyses were performed in order to examine the relationships between individual variables, organizational variables, and work engagement.ResultsNurse managers and nurses who felt that there was a positive relationship between work and family had significantly higher work engagement levels than others. The support of a supervisor was significantly associated with work engagement. Nurses in middle‐sized but not large agencies had significantly higher work engagement than nurses in small agencies.ConclusionSupervisor support and an appropriate number of people reporting to each supervisor are important factors in fostering work engagement among home‐visiting nurses.
Body Mass Index, Stunkard Figure Rating Scale, and Sexuality in Young Italian Women: A Pilot Study
Authors: Morotti Elena , Battaglia Bruno , Paradisi Roberto , Persico Nicola , Zampieri Marina , Venturoli Stefano , Battaglia Cesare 
Published: January 2013

ABSTRACT

Introduction
Increased body mass index is associated with a higher prevalence of metabolic diseases, depression, and sexual dysfunction. In obese patients, the perception of an altered body image may influence health and psychologically related behaviors. Furthermore, there is a significant positive relationship between sexual function, sexual satisfaction, and all body image variables.

Aim
To evaluate the relationship between body weight, perceived body image, and sexual behavior.

Methods
Ninety women underwent ultrasonographic clitoral volume measurement and color Doppler evaluation of the clitoral and ophthalmic arteries. The subjects filled the McCoy Female Sexuality Questionnaire (MFSQ), the Stunkard Figure Rating Scale (FRS), and the Beck's Depression Inventory (BDI) questionnaire.

Main Outcome Measures
Clitoral volume, clitoral and ophthalmic artery pulsatility index (PI), MFSQ, FRS, and BDI.

Results
The women were distributed into three groups: lean (N = 47); overweight (N = 22); and obese (N = 21). The ophthalmic artery showed lower PI in lean (1.72 ± 0.39) than in overweight (1.99 ± 0.30) and obese women (2.08 ± 0.19). The obese subjects presented the worst clitoral vascularization. The MFSQ for sexuality was higher in lean (45.8 ± 11.8) than in overweight (36.4 ± 15.0) and obese (36.1 ± 10.8) women. The frequency of intercourse per week was higher in lean (2.2 ± 1.4) than in overweight (1.3 ± 0.7) and obese (1.2 ± 0.4) women. The percentage of anorgasmic women was higher in obese (23%) than in lean subjects (6%). The FRS evidenced that the lean subjects represented themselves with a mean value (3.5 ± 1.0) lower than overweight (4.8 ± 0.7) and obese women (5.9 ± 0.6). The silhouette that represented their own ideal was significantly higher in obese (4.0 ± 0.4) than in overweight (3.3 ± 0.5) and lean (2.9 ± 0.7) subjects. The mean BDI was significantly higher in obese (15.8 ± 5.4) than in lean (8.4 ± 6.8) women.

Conclusions
Lifestyle modifications such as weight loss may be mandatory in obese subjects because obesity might impair the quality of sexual life by inducing genital and general vascular stiffness and body image distortion.
Impaired Masturbation-Induced Erections: A New Cardiovascular Risk Factor for Male Subjects with Sexual Dysfunction
Authors: Rastrelli Giulia , Boddi Valentina , Corona Giovanni , Mannucci Edoardo , Maggi Mario 
Published: January 2013

ABSTRACT

Introduction
Erectile dysfunction (ED) is considered an early surrogate marker of silent, or even overt, cardiovascular diseases (CVD). However, epidemiological studies take into account only sexual intercourse-related erections. Although autoeroticism is a very common practice, data on masturbation-induced erections as a possible predictor of major adverse cardiovascular events (MACE) are lacking.

Aim
To evaluate the clinical correlates of impaired masturbation-induced erections and to verify the importance of this sexual aspect in predicting MACE.

Methods
A consecutive series of 4,031 male patients attending the Outpatient Clinic for sexual dysfunction for the first time was retrospectively studied. Among these subjects, 64% reported autoeroticism during the last 3 months, and only this subset was considered in the following analyses. In the longitudinal study, 862 subjects reporting autoeroticism were enrolled.

Main Outcome Measures
Several clinical, biochemical, and instrumental (Prostaglandin E1 [PGE1] test and penile color Doppler ultrasound) parameters were studied.

Results
Subjects with an impaired erection during masturbation (46% of those reporting autoeroticism) had more often a positive personal or family history of CVD, a higher risk of reduced intercourse- and sleep-related erections, hypoactive sexual desire and perceived reduced ejaculate volume, and impaired PGE1 test response. Prolactin levels were lower in those having impaired erection during masturbation. In the longitudinal study, unadjusted incidence of MACE was significantly associated with impaired masturbation-induced erections. When dividing the population according to the median age and diagnosis of diabetes, the association between impaired masturbation-induced erections and incidence of MACE was maintained only in the youngest (&lt;55 years old) and in nondiabetic subjects, even after adjusting for confounders (hazard ratio [HR] = 3.348 [1.085–10.335], P = 0.032 and HR = 2.108 [1.002–4.433], P = 0.049; respectively).

Conclusion
This study indicates that, in subjects with male sexual dysfunction, evaluating an often neglected sexual parameter, such as masturbation-induced erections, can provide further insights on forthcoming MACE in particular in “low risk” subjects.
Surgical Solutions for the Complications of the Vaseline Self-Injection of the Penis
Authors: Bajory Zoltán , Mohos Gábor , Rosecker Ágnes , Bordás Noémi , Pajor László 
Published: January 2013

ABSTRACT

Introduction
Penile girth enhancement by the injection of Vaseline is an existing practice. Many cases develop severe complications that need surgery.

Aim
To report on the reconstructive surgical solutions of the complications of Vaseline self-injection and the outcomes. To develop a modification of a one-step reconstruction method involving the use of pedicled scrotal flaps.

Main Outcome Measures
The complications and their surgical solutions were classified as regards severity and difficulty. The outcomes were observed and a newly introduced one-step surgical method was investigated.

Methods
Seventy-eight consecutive patients (87.2% of them with a history of imprisonment) were divided into three groups. In group A, aesthetic penile defects or phimosis caused by the Vaseline necessitated circumcision or local excision. In group B, the whole penile skin was involved, and total skin removal and two- or (a newly modified) one-step reconstructive surgery were performed. In group C, both the whole penile skin and the scrotum were involved: complete skin removal and skin grafting or skin pedicled flap transplantation were carried out.

Results
In five cases in group B, postoperative skin necrosis made a second operation necessary. There was one intraoperative urethral injury, where a urethral fistula developed and a second urethral reconstruction was performed. There was no major complication with the newly developed one-stage pedicled flap procedure. At the end of the therapy, all the cases were healed. All of the patients reported successful sexual intercourse after the operations and 91% were satisfied with the result.

Conclusions
The complications depend mainly on the amount of Vaseline injected, the hygienic circumstances, and the personal tolerability. In the worst cases, only radical skin removal and skin transplantation can solve the problem. The newly developed one-step arterial branch-preserving scrotal skin flap reconstruction appears to be a suitable and cost-effective solution for these patients.
Liver transplantation for urea cycle disorders in pediatric patients: A single‐center experience
Authors: Kim Irene K. , Niemi Anna‐Kaisa , Krueger Casey , Bonham Clark A. , Concepcion Waldo , Cowan Tina M. , Enns Gregory M. , Esquivel Carlos O. 
Published: January 2013

AbstractLThas emerged as a surgical treatment forUCDs. We hypothesize thatLTcan be safely and broadly utilized in the pediatric population to effectively prevent hyperammonemic crises and potentially improve neurocognitive outcomes. To determine the long‐term outcomes ofLTforUCDs, charts of children withUCDwho underwentLTwere retrospectively reviewed at an academic institution betweenJuly 2001 andMay 2012. A total of 23 patients withUCDunderwentLTat a mean age of 3.4 yr. Fifteen (65%) patients received a whole‐liver graft, seven patients (30%) received a reduced‐size graft, and one patient received a living donor graft. Mean five‐yr patient survival was 100%, and allograft survival was 96%. Mean peak blood ammonia (NH3) at presentation was 772 μmol/L (median 500, range 178–2969, normal <30–50). After transplantation, there were no episodes of hyperammonemia. Eleven patients were diagnosed with some degree of developmental delay before transplantation, which remained stable or improved after transplantation. Patients without developmental delay before transplantation maintained their cognitive abilities at long‐term follow‐up.LTwas associated with the eradication of hyperammonemia, removal of dietary restrictions, and potentially improved neurocognitive development. Long‐term follow‐up is underway to evaluate whetherLTat an early age (<1 yr) will attain improved neurodevelopmental outcomes.
Intensity modulated radiotherapy (IMRT) combined with concurrent but not adjuvant chemotherapy in primary nasopharyngeal cancer – a retrospective single center analysis
Authors: Saleh-Ebrahimi Ladan , Zwicker Felix , Muenter Marc W , Bischof Marc , Lindel Katja , Debus Juergen , Huber Peter E , Roeder Falk 
Published: January 2013

Abstract

Background
We report our experience in 49 consecutive patients with nasopharyngeal carcinoma who were treated by Intensity-modulated radiation therapy (IMRT) combined with simultaneous but not adjuvant chemotherapy (CHT).

Methods
The medical records of 49 patients with histologically proven primary nasopharygeal carcinoma treated with IMRT and concurrent platin-based CHT (predominantly cisplatin weekly) were retrospectively reviewed. The majority of patients showed advanced clinical stages (stage III/IV:72%) with undifferentiated histology (82%). IMRT was performed in step-and-shoot technique using an integrated boost concept in 84%. In this concept, the boost volume covered the primary tumor and involved nodes with doses of 66–70.4 Gy (single dose 2.2 Gy). Uninvolved regional nodal areas were covered with doses of 54–59.4 Gy (median single dose 1.8 Gy). At least one parotid gland was spared. None of the patients received adjuvant CHT.

Results
The median follow-up for the entire cohort was 48 months. Radiation therapy was completed without interruption in all patients and 76% of the patients received at least 80% of the scheduled CHT. Four local recurrences have been observed, transferring into 1-, 3-, and 5-year Local Control (LC) rates of 98%, 90% and 90%. One patient developed an isolated regional nodal recurrence, resulting in 1-, 3-, and 5-year Regional Control (RC) rates of 98%. All locoregional failures were located inside the radiation fields. Distant metastases were found in six patients, transferring into 1-, 3, and 5-year Distant Control (DC) rates of 92%, 86% and 86%. Progression free survival (PFS) rates after 1, 3 and 5 years were 86%, 70% and 69% and 1-, 3- and 5-year Overall Survival (OS) rates were 96%, 82% and 79%. Acute toxicity ≥ grade III mainly consisted of dysphagia (32%), leukopenia (24%), stomatitis (16%), infection (8%) and nausea (8%). Severe late toxicity (grade III) was documented in 18% of the patients, mainly as xerostomia (10%).

Conclusion
Concurrent chemoradiation without the addition of adjuvant chemotherapy cycles using IMRT with an integrated boost concept yielded good disease control and overall survival in patients suffering from primary nasopharyngeal cancer with acceptable acute side effects and limited rates of late toxicity.
Standardized Flexibility: The Choreography of ICT in Standardization of Service Work
Authors: Røhnebæk Maria 
Published: January 2013

This article is based on a research project that explores the proliferation of information and communication technology (ICT) in public services. Furthermore, the research explores how the enhanced presence of ICT relates to efforts to increas-ingly individualise the service delivery. It can be argued that enhanced individualisation requires increased levels of discretion and flexibility. At the same time, this flexibility needs to be implemented within a standardized framework to ensure due process and to meet demands for efficiency. As local-level work practices in the public services are increasingly being enabled through ICT, the information systems can thus be seen to offer ’standardized flexibility’. Hence, the information systems work as both enablers of flexibility and as controllers of the same.
This research explores how this duality manifests empirically at the local-level of the Norwegian employment and welfare services (NAV). It focuses on the in-terface of the information systems and local-level employees. In this article, I portray the role of the information system, Arena, with regard to how the front-line employees structure and organize their work. This portrayal reveals that the information system reflects an ideal world which is out of tune with local working conditions. The employees are thus facing gaps between the ideals of the system and their actual work context. The main purpose of the paper is to illustrate how the employees deal with this gap; I identify three types of responses and strategies. Moreover, I suggest that the relationship between the information systems and different kinds of local responses may be fruitfully analysed by drawing an analogy with choreography and dancing. The second purpose of this article is thus to outline how the metaphor of choreography may provide a suitable theoretical lens for analysing ICT-enabled standardization of work.
Sur la vocation acéphale du théologien
Authors: Nault François 
Published: January 2013

Cet article porte sur la question de la « vocation du théologien », comme « appel existentiel », mais aussi comme acte d’inscription ecclésiale et universitaire. Il cherche à montrer comment la réflexion de Christoph Theobald apporte un éclairage sur ces questions.
The Inhibin B Response to a Motilin Receptor Agonist in Male Rats
Authors: Ziejewski Mary K. , Vidal Justin D. , Stanislaus Dinesh , Apostoli April , Chowdhury Probash , Laffan Susan 
Published: January 2013

BACKGROUNDIn a repeat oral dose toxicity study, all of 16 male rats given 100 mg/kg/day GSK1322888 sustained testicular injury after 4 weeks of treatment; the findings were not reversible after 12 weeks off‐dose. The current study was conducted to further characterize testicular toxicity and to explore the possible relationship between onset of lesions, and changes in circulating hormone levels.METHODSMale Sprague Dawley rats were orally administered 30 or 100 mg/kg/day GSK1322888 for 2 weeks with a 4‐week off‐dose period. Blood was collected via tail vein twice during the treatment period (days 4 and 11) and three times during the off‐dose period (days 28, 36, and 42) for measurement of serum testosterone, dihydrotestosterone, and Inhibin B, luteinizing hormone, and follicle stimulating hormone concentrations. A histopathologic examination of testes was performed at the end of the treatment and off‐dose periods.RESULTSAt 100 mg/kg/day, microscopic findings of the testis (degeneration of the germinal epithelium) were evident for 9 of 10 male rats on day 14 and all 10 rats at the end of the 4‐week recovery period. There was no testicular toxicity observed at 30 mg/kg/day. During all stages of evaluation, there was no apparent difference among control and treated animals in hormone concentrations.CONCLUSIONThere was poor correlation between changes in serum levels of Inhibin B and testis histopathology. Based on these observations, the utility of Inhibin B as a hormonal marker for germ cell toxicity is limited.
The Inhibin B (InhB) Response to the Testicular Toxicants Mono‐2‐Ethylhexyl Phthalate (MEHP), 1,3 Dinitrobenzene (DNB), or Carbendazim (CBZ) Following Short‐term Repeat Dosing in the Male Rat
Authors: Breslin William J. , Paulman April , Sun‐Lin Denise , Goldstein Keith M. , Derr Angela 
Published: January 2013

OBJECTIVEThe objective of this study was to evaluate the utility of plasma Inhibin B (InhB) as a biomarker of testicular injury in adult rats following short‐term exposure to the known Sertoli cell toxicants mono‐2‐ethylhexyl phthalate (MEHP), 1,3 dinitrobenzene (DNB), or carbendazim (CBZ).METHODSFollowing oral gavage administration of the compounds for 2 or 7 days, the rats were evaluated for clinical signs, body weight, food consumption, organ weights, plasma hormone levels, and gross and microscopic pathology.RESULTSMEHP,DNB, andCBZproduced a range of testicular toxicity characterized by minimal exfoliation of germ cells as demonstrated by increased cellular debris in the epididymis (MEHP) to more severe and dose/duration responsive Sertoli cell vacuolation, germ cell degeneration, and multinucleated giant cells of germ cell origin (DNBandCBZ). The slight to moderate Sertoli and germinal cell injuries did not correlate with significant changes in plasma InhB levels following 2‐ or 7‐day exposures. However, more severe injury to germinal epithelium following up to 7 days of exposure, but not after 2 days of exposure, correlated with decreased plasma InhB levels and less consistently with increases in plasma follicle stimulating hormone.CONCLUSIONIn conclusion, under the conditions of these studies, changes in InhB were not an effective early onset marker of testicular toxicity or an effective marker for slight to moderate levels of acute injury, and only reflected more severe disruption of spermatogenesis. Changes in plasma InhB and follicle stimulating hormone were poorly correlated except in some instances of moderate to marked testicular toxicity.
Convenient One‐Pot Synthesis of α‐Amino Phosphonates in Water Using p‐Toluenesulfonic Acid as Catalyst for the Kabachnik–Fields Reaction
Authors: Wu Mingshu , Liu Rendie , Wan Dehui 
Published: January 2013

ABSTRACTThe three‐component Kabachnik–Fields reaction of substituted salicylaldehydes, aromatic amine, and triphenyl phosphite in water was effectively catalyzed by p‐toluenesulfonic acid to give various α‐amino phosphonates in good yields. The catalyst is easily available and inexpensive, and the process is green and mild. © 2013 Wiley Periodicals, Inc. Heteroatom Chem 24:110–115, 2013; View this article online at wileyonlinelibrary.com. DOI 10.1002/hc.21071
Reduced toxicity and superior cellular response of preosteoblasts to Ti‐6Al‐7Nb alloy and comparison with Ti‐6Al‐4V
Authors: Challa V. S. A. , Mali S. , Misra R. D. K. 
Published: January 2013

AbstractThere are serious concerns on the toxicity of vanadium in Ti‐6Al‐4V alloy. In this regard, we describe the biological footprint of Ti‐6Al‐4V and compare with a viable alternate Ti‐6Al‐7Nb alloy, in terms of novel experimentation pertaining to cellular activity that include qualitative and quantitative analysis of Feret's diameter of cells, area, and perimeter, and proteins—actin, vinculin, and fibronectin. Interestingly, Ti‐6Al‐7Nb was characterized by superior cell attachment, proliferation, viability, morphology, and spread, which were significantly different from Ti‐6Al‐4V alloy. Additionally, immunofluorescence studies demonstrated stronger vinculin signals associated with actin stress fibers in the outer regions of the cells and cellular extensions in Ti‐6Al‐7Nb alloy. These striking observations suggest enhanced cell–substrate interaction and activity on the surface of niobium‐containing titanium alloy. The significant differences in the cellular response between the two alloys clearly point to the determining role of alloying element (Nb versus V) in a conclusive manner. Based on this study, next generation of titanium alloys is proposed to focus on niobium‐containing alloy. © 2013 Wiley Periodicals, Inc. J Biomed Mater Res Part A, 2013.
The Influence of Demand Characteristics and Social Desirability on Clients’ Ratings of the Therapeutic Alliance
Authors: Reese Robert J. , Gillaspy J. Arthur , Owen Jesse J. , Flora Kevin L. , Cunningham Linda C. , Archie Danielle , Marsden TroyMichael 
Published: January 2013

ObjectiveTo examine demand characteristics, social desirability on clients’ rating of working alliance using the Session Rating Scale (SRS; Miller, Duncan, & Johnson, 2000).MethodClients (N = 102) at two sites were randomly assigned to one of three alliance feedback conditions: (a) IF—SRS completed in presence of therapist and the results discussed immediately afterward; (b) Next Session Feedback—SRS completed alone and results discussed next session; or (c) No Feedback—SRS completed alone and results not available to therapist. Clients completed the SRS for the first three sessions of treatment.ResultsNo statistically significant differences in SRS scores across the feedback conditions were found. Additionally, the analysis showed that SRS scores were not correlated with a measure of social desirability but were correlated with an established alliance measure.ConclusionsThe results indicate that alliance scores were not inflated due to the presence of a therapist or knowing that the scores would be observed by the therapist.
Priming of Courageous Behavior: Contrast Effects in Spider Fearful Women
Authors: Cougle Jesse R. , Hawkins Kirsten A. 
Published: January 2013

ObjectiveRecently, researchers have called for therapeutic applications of behavioral primes (Shalev & Bargh, 2011). We evaluated whether courageous approach behavior might be facilitated through priming in a sample of spider fearful women.MethodUndergraduate student women reporting elevated spider fear (N = 33, Age mean = 18.88) were recruited for this study. Participants completed self‐report measures of spider fear and dispositional courage. They then completed either a courage or neutral word search prime, which was followed by a behavioral approach task involving a tarantula.ResultsConsistent with predictions, among those reporting lower dispositional courage, the courage prime led to reduced approach behavior relative to the neutral prime. However, no group differences were found among those high in dispositional courage.ConclusionsThese findings point to the importance of self‐perceptions in moderating the effects of behavioral primes and suggest limitations to the use of such interventions with individuals with psychological dysfunction.