bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of plant nitrogen and water status on the foraging behavior and fitness of an omnivorous arthropod
Authors: Han Peng , Dong Yongcheng , Lavoir Anne‐Violette , Adamowicz Stéphane , Bearez Philippe , Wajnberg Eric , Desneux Nicolas 
Published: November 2015

AbstractOmnivorous arthropods make dietary choices according to the environment in which they forage, mainly availability/quality of plant and/or prey resources. Such decisions and their subsequent impacts on life‐history traits may be affected by the availability of nutrients and water to plants, that is, through bottom‐up forces. By setting up arenas for feeding behavior observation as well as glasshouse cages for plant preference assessment, we studied effects of the presence of prey (Lepidoptera eggs) and nitrogen/water availability to host tomato plants on the foraging behavior and life‐history traits in the omnivorous predatorMacrolophus pygmaeus(Heteroptera: Miridae). In the absence of prey, the predator fed equally on the plants treated with various levels of nitrogen and water. In the presence of prey, however, the feeding rate on plants decreased when the plant received low water input. The feeding rate on prey was positively correlated with feeding rate on plants; that is, prey feeding increased with plant feeding when the plants received high water input. Moreover, plants receiving high water input attracted moreM. pygmaeusadults compared with those receiving low water input. ForM. pygmaeusfitness, the presence of prey enhanced its fertility and longevity, but the longevity decreased when plants received low compared with high water input. In conclusion, the omnivorous predator may be obliged to feed on plants to obtain water, and plant water status may be a limiting factor for the foraging behavior and fitness of the omnivorous predator.
Bis(quinoxaline‐dithiolato)nickel(III) Complexes [Bu4N][NiIII(6,7‐qdt)2] and [Ph4P]­[NiIII(Ph26,7‐qdt)2]·CHCl3 (6,7‐qdt = Quin­oxaline‐6,7‐dithiolate; Ph26,7‐qdt = Diphenylquinoxaline‐6,7‐dithiolate): Synthesis, Spectroscopy, Electrochemistry, DFT Calculations, Crystal Structures and Hirshfeld Surface Analysis
Authors: Naik Indravath Krishna , Sarkar Rudraditya , Das Samar K. 
Published: November 2015

AbstractTwo bis(quinoxaline‐dithiolato)nickel(III) complexes [Bu4N][NiIII(6,7‐qdt)2] (1; 6,7‐qdt = quinoxaline‐6,7‐dithiolate) and [Ph4P][NiIII(Ph26,7‐qdt)2]·CHCl3 (2; Ph26,7‐qdt = diphenylquinoxaline‐6,7‐dithiolate) have been synthesized from their NiII analogues by iodine oxidation. Compounds 1 and 2 have been characterized by routine spectral analysis and single‐crystal X‐ray structure determination. Nickel(III) complexes 1 and 2 exhibit redshifted absorption bands compared with their NiII analogues; the electronic absorption spectral studies have been corroborated by DFT calculations. Electrochemical studies on 1 and 2 are consistent with those of their NiII analogues. Electron spin resonance (ESR) studies confirm that nickel is present in both 1 and 2 in its +3 oxidation state. This is also consistent with the fact that only one cation (Bu4N+ for 1 and Ph4P+ for 2) is present in the respective crystal structures. The crystal structures of both compounds are characterized by C–H···S and C–H···N hydrogen‐bonding interactions. Hirshfeld surface analyses have been studied to gain deep insight into the hydrogen‐bonding interactions around/among the coordination complex anions.
A Dimetallic Osmium(II) Complex as a Potential Phototherapeutic Agent: Binding and Photocleavage Studies with Plasmid DNA
Authors: Swavey Shawn , Li Kaiyu 
Published: November 2015

AbstractA new dimetallic OsIIcomplex bridged by (4‐hydroxy‐3‐methoxyphenyl)diphenanthropyrromethane [{Os(bpy)2php}2van](PF6)4has been synthesized and characterized by UV/Vis spectroscopy, cyclic voltammetry, and elemental analysis. The spectroscopic properties are similar to those of [Os(bpy)3]2+with ligand‐centered π–π* transitions in the UV region of the spectrum and three metal‐to‐ligand charge‐transfer (1MLCT) transitions in the visible region. A broad3MLCT is observed stretching from 550 to 700 nm with modest intensity. Binding studies with calf thymus DNA (ctDNA) show binding constants as high as 105M–1indicating a strong interaction of the complex with DNA. When aqueous solutions of the complex and plasmid DNA are irradiated with low‐energy light for brief periods of time complete photocleavage of the DNA is observed. Studies indicate that the mechanism of this photoreaction requires molecular oxygen and results from both the formation of1O2and oxygen radicals offering multiple modes for DNA destruction.
A high‐order discontinuous Galerkin solver for low Mach number flows
Authors: Klein B. , Müller B. , Kummer F. , Oberlack M. 
Published: November 2015

SummaryIn this work, we present a high‐order discontinuous Galerkin method (DGM) for simulating variable density flows at low Mach numbers. The corresponding low Mach number equations are an approximation of the compressible Navier–Stokes equations in the limit of zero Mach number. To the best of the authors'y knowledge, it is the first time that the DGM is applied to the low Mach number equations. The mixed‐order formulation is applied for spatial discretization. For steady cases, we apply the semi‐implicit method for pressure‐linked equation (SIMPLE) algorithm to solve the non‐linear system in a segregated manner. For unsteady cases, the solver is implicit in time using backward differentiation formulae, and the SIMPLE algorithm is applied to solve the non‐linear system in each time step. Numerical results for the following three test cases are shown: Couette flow with a vertical temperature gradient, natural convection in a square cavity, and unsteady natural convection in a tall cavity. Considering a fixed number of degrees of freedom, the results demonstrate the benefits of using higher approximation orders. Copyright © 2015 John Wiley & Sons, Ltd.
The Relative Predictability of Stock Markets in the Americas
Authors: Smith Graham , Dyakova Aneta 
Published: November 2015

AbstractThe degree of return predictability is measured for seven Latin American stock markets and those in Canada and the United States using three finite‐sample variance ratio tests. Daily data for the period beginning in February 1994 and ending in December 2011 are used in a fixed‐length rolling window to capture short‐lived predictability, track changes in predictability through time and rank markets by relative predictability. Overall, the degree of return predictability varies widely. The most predictable are those located in Chile and Peru; the least predictable are in Argentina and Brazil. Predictability has decreased for all of those stock markets examined, except those located in Ecuador and the United States. Predictability largely coincides with times of crisis. Copyright © 2015 John Wiley & Sons, Ltd.
Optical reprogramming of human cells in an ultrashort femtosecond laser microfluidic transfection platform
Authors: Uchugonova Aisada , Breunig Hans Georg , Batista Ana , König Karsten 
Published: November 2015

Induced pluripotent stem cell (iPS cell) technology can be used to produce unlimited numbers of functional cells for both research and therapeutic purposes without ethical controversy. Typically, viruses are applied for efficient intracellular delivery of genes/transcription factors to generate iPS cells. However, the viral genomic integration may cause a risk of mutation as well as tumor formation therefore limits its clinical application.Here we demonstrate that spatially shaped extreme ultrashort laser pulses of sub‐20 femtoseconds induce transient membrane permeabilisation which enables contamination‐free transfection of cells in a microfluidic tube with multiple genes at the individual cell level in order to achieve optical reprogramming of large cell populations. We found that the ultrashort femtosecond laser‐microfluidic cell transfection platform enhanced the efficacy of iPS‐like colony‐forming following merely a single transfection.
Illustration of the spatially shaped femtosecond laser‐assisted microfluidic cell transfection platform for production of iPS cell colonies.magnified imageIllustration of the spatially shaped femtosecond laser‐assisted microfluidic cell transfection platform for production of iPS cell colonies.
Macrophages: Their Emerging Roles in Bone
Authors: Sinder Benjamin P , Pettit Allison R , McCauley Laurie K 
Published: November 2015

ABSTRACT

Macrophages are present in nearly all tissues and are critical for development, homeostasis, and regeneration. Resident tissue macrophages of bone, termed osteal macrophages, are recently classified myeloid cells that are distinct from osteoclasts. Osteal macrophages are located immediately adjacent to osteoblasts, regulate bone formation, and play diverse roles in skeletal homeostasis. Genetic or pharmacological modulation of macrophages in vivo results in significant bone phenotypes, and these phenotypes depend on which macrophage subsets are altered. Macrophages are also key mediators of osseous wound healing and fracture repair, with distinct roles at various stages of the repair process. A central function of macrophages is their phagocytic ability. Each day, billions of cells die in the body and efferocytosis (phagocytosis of apoptotic cells) is a critical process in both clearing dead cells and recruitment of replacement progenitor cells to maintain homeostasis. Recent data suggest a role for efferocytosis in bone biology and these new mechanisms are outlined. Finally, although macrophages have an established role in primary tumors, emerging evidence suggests that macrophages in bone support cancers which preferentially metastasize to the skeleton. Collectively, this developing area of osteoimmunology raises new questions and promises to provide novel insights into pathophysiologic conditions as well as therapeutic and regenerative approaches vital for skeletal health. © 2015 American Society for Bone and Mineral Research.
Multiphoton imaging with a novel compact diode‐pumped Ti:sapphire oscillator
Authors: König Karsten , Andersen Peter , Le Tuan , Breunig Hans Georg 
Published: November 2015

ABSTRACTMultiphoton laser scanning microscopy commonly relies on bulky and expensive femtosecond lasers. We integrated a novel minimal‐footprint Ti:sapphire oscillator, pumped by a frequency‐doubled distributed Bragg reflector tapered diode laser, into a clinical multiphoton tomograph and evaluated its imaging capability using different biological samples, i.e. cell monolayers, corneal tissue, and human skin. With the novel laser, the realization of very compact Ti:sapphire‐based systems for high‐quality multiphoton imaging at a significantly size and weight compared to current systems will become possible. Microsc. Res. Tech. 78:1154–1158, 2015. © 2015 Wiley Periodicals, Inc.
Lung Function Testing On and Off Dopaminergic Medication in Parkinson's Disease Patients With and Without Dysphagia
Authors: Sawan Tareq , Harris Mary Louise , Kobylecki Christopher , Baijens Laura , van Hooren Michel , Michou Emilia 
Published: November 2015

AbstractBackgroundSwallowing function in individuals with Parkinson's disease (PD) can be negatively affected by dopaminergic medication with associated inhibition of brainstem reflexes. Three different “swallowing‐safety” profiles of PD patients were previously observed, classified according to swallowing safety on and off levodopa.MethodsHere, we investigated the effects of l‐dopa on pulmonary function tests (PFTs) on 26 individuals with PD from the three different swallowing‐safety profiles. PFTs results were compared to predicted values and direct comparisons between the groups with or without dysphagia were performed with nonparametric statistical tests (i.e., Kruskal–Wallis).ResultsA short (12‐hour) withdrawal from l‐dopa did not result in any significant changes in PFTs, and no differences on PFTs results were observed between the different dysphagic groups the on and off l‐dopa state. No correlation was observed between the PFTs results with swallowing safety profiles of PD patients.ConclusionsAlthough deglutition seems to be at least partially affected by dopaminergic repletion, dopaminergic mechanisms do not seem to be responsible for PD patients' performance in PFTs.
A two‐surface thermomechanical model for saturated clays
Authors: Hong P. Y. , Pereira J. M. , Cui Y. J. , Tang A. M. 
Published: November 2015

SummaryThis paper presents an advanced thermomechanical model – TEAM in the framework of two‐surface plasticity for saturated clays, with emphasis put on some important thermomechanical features of natural clays evidenced experimentally such as the limited thermomechanical elastic zone, the smooth transition from elastic to plastic behavior. Two plastic mechanisms are introduced in the model: one is to reproduce the thermoplasticity involving thermal expansion and contraction observed at high over‐consolidation ratios and the second one describes the temperature effect on the yield behavior. The model adopts additional yield surfaces, namely inner yield surfaces that are associated with the two proposed plastic mechanisms to account for the plastic behavior inside the existing conventional thermomechanical yield surface namely yield surfaces. The general expressions of the yield surfaces and plastic potentials in p′–q–T space are introduced. A progressive plastic hardening mechanism associated with the inner yield surface is defined, enabling the plastic modulus to vary smoothly during thermomechanical loadings inside the yield surfaces. Several tests on natural Boom clay along different thermomechanical loading paths have been simulated by TEAM, and results show its relevance in describing the thermomechanical behavior of saturated clays. Copyright © 2015 John Wiley & Sons, Ltd.
Inhibitory effects of retigabine, a Kv7 channel activator, on mechanosensitive primary bladder afferent activities and nociceptive behaviors in rats
Authors: Aizawa Naoki , Wakamatsu Daisuke , Kida Jun , Otsuki Takeya , Saito Yasuho , Matsuya Hidekazu , Homma Yukio , Igawa Yasuhiko 
Published: November 2015

AimsKv7 voltage‐gated potassium channels have been suggested to modulate mechano‐afferent transduction and nociception in the bladder. We investigated the effects of retigabine, a Kv7 channel activator, on rhythmic bladder contractions (RBCs), and single‐unit afferent activities (SAAs) of the primary bladder mechanosensitive afferent nerve fibers in urethane‐anesthetized rats. In addition, the effects of pretreatment with retigabine on the nociceptive behaviors provoked by an intravesical instillation of resiniferatoxin (RTX) were evaluated in the conscious condition.MethodsFemale Sprague–Dawley rats were used. Under urethane anesthesia, saline was instilled into the bladder until RBCs were induced reproducibly. Then, the effects of intravenous, cumulative administrations of retigabine (0.1–3 mg/kg) or vehicle (saline) on RBCs were assessed. In separate animals, SAAs of Aδ‐ and C‐fibers were identified by electrical stimulation of the pelvic nerve and by bladder distention with saline. After baseline recording, vehicle or retigabine (0.01–1 mg/kg) was administered intravenously and further recordings were performed. Under pretreatment with vehicle or retigabine (3 mg/kg intraperitoneally), the frequencies of lower abdominal licking and freezing were counted and scored as the bladder nociceptive behaviors induced by intravesical RTX instillation (3 µM, 0.3 ml).ResultsRetigabine dose‐dependently decreased both the frequency and the amplitude of RBCs and SAAs of both Aδ‐ and C‐fibers. The effect on RBCs was more potent on the frequency than the amplitude. Retigabine inhibited the RTX‐induced abdominal licking, but not freezing.ConclusionKv7 channels are likely to be implicated in inhibition of bladder mechano‐ and nociceptive sensory transduction. Neurourol. Urodynam. 36:280–285, 2017. © 2015 Wiley Periodicals, Inc.
A locally anisotropic fluid–structure interaction remeshing strategy for thin structures with application to a hinged rigid leaflet
Authors: Auricchio Ferdinando , Lefieux Adrien , Reali Alessandro , Veneziani Alessandro 
Published: November 2015

SummaryAn immersed finite element fluid–structure interaction algorithm with an anisotropic remeshing strategy for thin rigid structures is presented in two dimensions. One specific feature of the algorithm consists of remeshing only the fluid elements that are cut by the solid such that they fit the solid geometry. This approach allows to keep the initial (given) fluid mesh during the entire simulation while remeshing is performed locally. Furthermore, constraints between the fluid and the solid may be directly enforced with both an essential treatment and elements allowing the stress to be discontinuous across the structure. Remeshed elements may be strongly anisotropic. Classical interpolation schemes – inf–sup stable on isotropic meshes – may be unstable on anisotropic ones. We specifically focus on a proper finite element pair choice. As for the time advancing of the fluid–structure interaction solver, we perform a geometrical linearization with a sequential solution of fluid and structure in a backward Euler framework. Using the proposed methodology, we extensively address the motion of a hinged rigid leaflet. Numerical tests demonstrate that some finite element pairs are inf–sup unstable with our algorithm, in particular with a discontinuous pressure. Copyright © 2015 John Wiley & Sons, Ltd.
Trends in rates of acetaminophen‐related adverse events in the United States
Authors: Major Jacqueline M. , Zhou Esther H. , Wong Hui‐Lee , Trinidad James P. , Pham Tracy M. , Mehta Hina , Ding Yulan , Staffa Judy A. , Iyasu Solomon , Wang Cunlin , Willy Mary E. 
Published: November 2015

AbstractPurposeThe goal of this study is to summarize trends in rates of adverse events attributable to acetaminophen use, including hepatotoxicity and mortality.MethodsA comprehensive analysis of data from three national surveillance systems estimated rates of acetaminophen‐related events identified in different settings, including calls to poison centers (2008–2012), emergency department visits (2004–2012), and inpatient hospitalizations (1998–2011). Rates of acetaminophen‐related events were calculated per setting, census population, and distributed drug units.ResultsRates of poison center calls with acetaminophen‐related exposures decreased from 49.5/1000 calls in 2009 to 43.5/1000 calls in 2012. Rates of emergency department visits for unintentional acetaminophen‐related adverse events decreased from 58.0/1000 emergency department visits for adverse drug events in 2009 to 50.2/1000 emergency department visits in 2012. Rates of hospital inpatient discharges with acetaminophen‐related poisoning decreased from 119.8/100 000 hospitalizations in 2009 to 108.6/100 000 hospitalizations in 2011. After 2009, population rates of acetaminophen‐related events per 1 million census population decreased for poison center calls and hospitalizations, while emergency department visit rates remained stable. However, when accounting for drug sales, the rate of acetaminophen‐related events (per 1 million distributed drug units) increased after 2009. Prior to 2009, the rates of acetaminophen‐related hospitalizations had been slowly increasing (p‐trend = 0.001).ConclusionsAcetaminophen‐related adverse events continue to be a public health burden. Future studies with additional time points are necessary to confirm trends and determine whether recent risk mitigation efforts had a beneficial impact on acetaminophen‐related adverse events. Published 2015. This article is a U.S. Government work and is in the public domain in the USA.
Stable chlorine isotope analysis of chlorinated acetic acids using gas chromatography/quadrupole mass spectrometry
Authors: Miska Milena E. , Shouakar‐Stash Orfan , Holmstrand Henry 
Published: November 2015

RationaleThe environmental occurrence of chlorinated acetic acids (CAAs) has been extensively studied, but the sources and transport are still not yet fully understood. A promising approach for source apportionment and process studies is the isotopic characterization of target compounds. We present the first on‐line stable chlorine isotope analysis of CAAs by use of gas chromatography/quadrupole mass spectrometry (GC/qMS).MethodsFollowing approved procedures for concentration analysis, CAAs extracted into MTBE were methylated to GC‐amenable methyl esters (mCAAs). These mCAAs were then analyzed by GC/qMS for their stable chlorine isotope composition using a sample/standard‐bracketing approach (CAA standards in the range δ37Cl −6.3 to −0.2 ‰, Standard Mean Ocean Chloride).ResultsCross‐calibration of the herein presented method with off‐line reference methods (thermal ionization and continuous‐flow GC isotope ratio mass spectrometry; TI‐MS and CF‐GC/IRMS, respectively) shows good agreement between the methods (regression slope for GC/qMS vs reference method data sets: 0.92 ± 0.29). Sample amounts as small as 10 pmol Cl can herewith be analyzed with a precision of 0.1 to 0.4 ‰.ConclusionsThis method should be useful for environmental studies of CAAs at ambient concentrations in precipitations (<0.06 to 100 nmol L–1), surface waters (<0.2 to 5 nmol L–1) and soil (<0.6 to 2000 nmol kg–1 dry soil) where conventional off‐line methods cannot be applied. Copyright © 2015 John Wiley & Sons, Ltd.
Attack on Chen et al.'s certificateless aggregate signature scheme
Authors: Zhang Jianhong , Zhao Xubing , Mao Jian 
Published: November 2015

AbstractCertificateless aggregate signature can provide an efficient way to verify a large amount of signatures from different users. This feature makes it very useful in the environments with low bandwidth communication, low storage, and low computability. Recently, Chen et al. proposed a new certificateless aggregate signature scheme. They claim that their scheme is provably secure under the computational Diffie–Hellman problem. Unfortunately, this paper shows that Chen et al.'s scheme is insecure, it cannot resist Type I and Type II adversaries, and the corresponding attacks are given. Furthermore, we also show their scheme exists a more powerful attack, namely, anyone can forge a certificateless signature on an arbitrary message in this attack. Finally, we discuss the reason to produce such attacks and give the corresponding suggestions to resist such attacks. Copyright © 2015 John Wiley & Sons, Ltd.