bluuebunny/crossref_metadata_2025_split huggingface dataset:
Machine learning-based analysis of Ebola virus' impact on gene expression in nonhuman primates
Authors: Rezapour Mostafa , Niazi Muhammad Khalid Khan , Lu Hao , Narayanan Aarthi , Gurcan Metin Nafi 
Published: August 2024

IntroductionThis study introduces the Supervised Magnitude-Altitude Scoring (SMAS) methodology, a novel machine learning-based approach for analyzing gene expression data from non-human primates (NHPs) infected with Ebola virus (EBOV). By focusing on host-pathogen interactions, this research aims to enhance the understanding and identification of critical biomarkers for Ebola infection.MethodsWe utilized a comprehensive dataset of NanoString gene expression profiles from Ebola-infected NHPs. The SMAS system combines gene selection based on both statistical significance and expression changes. Employing linear classifiers such as logistic regression, the method facilitates precise differentiation between RT-qPCR positive and negative NHP samples.ResultsThe application of SMAS led to the identification of IFI6 and IFI27 as key biomarkers, which demonstrated perfect predictive performance with 100% accuracy and optimal Area Under the Curve (AUC) metrics in classifying various stages of Ebola infection. Additionally, genes including MX1, OAS1, and ISG15 were significantly upregulated, underscoring their vital roles in the immune response to EBOV.DiscussionGene Ontology (GO) analysis further elucidated the involvement of these genes in critical biological processes and immune response pathways, reinforcing their significance in Ebola pathogenesis. Our findings highlight the efficacy of the SMAS methodology in revealing complex genetic interactions and response mechanisms, which are essential for advancing the development of diagnostic tools and therapeutic strategies.ConclusionThis study provides valuable insights into EBOV pathogenesis, demonstrating the potential of SMAS to enhance the precision of diagnostics and interventions for Ebola and other viral infections.
The prevalence of dental caries and its associated factors among preschool children in Huizhou, China: a cross-sectional study
Authors: Chen Jieyi , Chen Wanting , Lin Lude , Ma Haozhen , Huang Fang 
Published: August 2024

BackgroundDental caries among preschool children were prevalent worldwide and had a significant impact on children and their families. Understanding its prevalence and risk factors helps to optimize the delivery of oral health care to the target population and promote their oral health ultimately. This cross-sectional study aimed to examine the prevalence of dental caries and its associated factors among 3- to 5-year-old children in Huizhou, Guangdong Province, China.MethodWe recruited children from 21 kindergartens adopting multistage sampling method. Two examiners performed oral examination. They assessed children's dental caries experience following the World Health Organization criteria. Children's dental caries activity, malocclusion, tonsil size and pH value of saliva were evaluated. Parental questionnaires collected child's sociodemographic background and oral-health-related behaviors. Data were analyzed by univariate analysis and logistic regression using SPSS.ResultsThis study invited 1,485 children and recruited 1,348 (53.2% boys) (response rate: 90.8%). Dental caries prevalence rate was 58.2% for 3-, 70.7% for 4-, 80.5% for 5-year-old and 72.9% for all recruited children. The mean dmft score (±SD) was 3.38 (±4.26) for 3-, 4.75 (±4.96) for 4-, 5.81 (±5.71) for 5-year-old and 4.99 (±5.02) for all children. Age, family status (singleton or not), monthly family income, mother and father's education level, tonsil grading score, spacing in dentition, Cariostat score (reflecting the caries activity), dental plaque index, duration of breastfeeding, dental visit experience, tooth brushing habits and sugary snacking before sleeping were statistically related to the prevalence of dental caries (p &lt; 0.050) in univariate analysis. These factors were further analyzed in the regression model. The results of the final model indicated dental caries were associated with age (p &lt; 0.001), Cariostat score (p &lt; 0.001), spacing (p &lt; 0.001), tonsil grading score (p = 0.013), singleton or not (p = 0.002), sugary snacking habit before bed (p &lt; 0.001) and breast-feeding duration (p = 0.050).ConclusionDental caries was prevalent among 3-to 5-year-old preschool children in Huizhou, China. Children's age, caries activity, tonsil size, malocclusion, family background, sugary snacking habit and breast-feeding habit were related to the prevalence of dental caries. More emphasis should be placed on prevention targeting the risk factors from early life.
SETTLEMENT OF NUTRITED CREDITS OF SYARI'AH FINANCING THE IJARAH MUNTAHIYA BITTAMLIC MODEL WITH LIABILITY RIGHTS IN STATE BIDDING DEBT AFFAIRS AGENCY
Authors: Fahruddin Muhammad , Fitrini Vini 
Published: August 2024

Sharia Bank is an Islamic bank that is starting to be in great demand by Indonesians, especially Muslims. Financing. In the running of the IMBT contract, bad credit problems often occur by the customer to the bank with guarantees of security rights to pay off their obligations. Usually the bank will ask the Head of the Religious Court to carry out the execution. When there is no good faith from the customer to the bank, the bank asks the Head of the Religious Court to submit a written auction request to (KPKNL) to sell auction of goods that have been executed. In this paper, the author focuses on the formulation of the problem, namely: 1. How is the IMBT model of shari'ah financing mechanism with guarantees of mortgage rights? auction implementation of the mortgage rights of Ijarah Muntahiya Bittamlik syari'ah financing with guarantees of coverage rights at BUPLN ?

Bank Syariah merupakan bank Islam yang mulai banyak diminati oleh masyarakat Indonesia khususnya kaum muslim. Dalam berjalannya akad IMBT sering terjadi kendala kredit macet yang dilakukan oleh nasabah kepada bank dengan jaminan hak tanggungan untuk melunasi kewajibannya. Biasanya bank akan meminta kepada Ketua Pengadilan Agama untuk dilakanakannya eksekusi. Ketika tidak ada itikad baik dari nasabah kepada bank, bank memohon Ketua Pengadilan Agama untuk mengajukan permohonan lelang secara tertulis kepada (KPKNL) untuk mejual lelang barang-barang yang telah di sita eksekusi. Dalam penulisan ini, penulis menitikberatkan kepada rumusan masalah yaitu: 1. Bagaimana mekanisme pembiayaan syari’ah model IMBT dengan jaminan hak tanggungan?, 2. Bagaimana penyelesaian kredit macet pembiayaan syari’ah IMBT di pengadilan agama dengan jaminan hak tanggungan?, 3. Bagaimana implemestasi pelelangan terhadap hak tanggungan dari pembiayaan syari’ah Ijarah Muntahiya Bittamlik dengan jaminan hak tangungan di BUPLN?
PENGARUH HARGA DAN KUALITAS PRODUK TERHADAP KEPUTUSAN PEMBELIAN KURSUS ONLINE (Pada PT Kemitraan Kuliner Indonesia)
Authors: Chusnah C , Sunarno S , Nambi Hamzah Fansuri 
Published: August 2024

The purpose of this study was to determine the effect of price and product quality on the purchasing decision to take an online course at PT Kemitraan Kuliner Indonesia. The population in this study are consumers who’s been buying the frozen food secret recipe online course in the last 2 years at PT Kemitraan Kuliner Indonesia. The sample in this study consisted of 100 respondents. The analysis methods used in this study are validity test and reliability test, normality test, multicollinearity test, heteroscedasticity test, multiple regression analysis and multiple correlation analysis, determination analysis, f test and t test using the SPSS 25 program. Based on the results of the price variable t test research can a concluded that price has a positive and significant effect on the purchasing decision to take the course. Product quality variable t test can be concluded that Product Quality has a positive and significant effect on the purchasing decision to take an online course at PT Kemitraan Kuliner Indonesia. Based on the results of the coefficient of determination (R2) of 0.859, it shows that the Price and Product Quality variables are able to partially explain 85.9% of the variation that occurs in Purchasing Decisions, while 14.1% is another factor.
Hubungan Beban Kerja dengan Stres Kerja pada Perawat di Ruang Instalasi Rawat Inap Bedah di RSUP M. Djamil Padang Tahun 2022
Authors: Mindayani Sri , Aisyiah Intan Kamala , Safutri Shinta Okvianti 
Published: August 2024

The results of a survey conducted by the Indonesian National Nurses Association (PPNI) in 2018 about 50.9% of nurses in Indonesia experience work stress. RSUP Dr. M. Djamil Padang is a referral hospital for the Central Sumatra region, serving people in the provinces of West Sumatra, Riau, Jambi, Bengkulu, and the southern part of North Sumatra. IRNA surgery at RSUP Dr. M. Djamil Padang has 180 patient beds. In the initial survey conducted by researchers, some nurses experienced symptoms of work stress such as feeling tired, dizzy, irritable, no appetite, exhausted. The purpose of this study was to determine the relationship between workload and tenure with work stress on nurses in IRNA surgery at RSUP Dr. M. Djamil Padang in 2022. The type of research used is quantitative with a cross sectional design. The study was conducted from January to August 2022 on surgical IRNA nurses at RSUP Dr. M. Djamil Padang. The population in this study amounted to 87 nurses, using a total sampling technique with inclusion and exclusion criteria. Data processing using SPSS. The research instrument used a questionnaire. The analysis used is univariate and bivariate analysis with Chi-Square test. The results showed that 51.8% of nurses experienced work stress, 56.5% of nurses had a heavy workload and 54.1% of nurses with a working period of > 5 years. The results of the bivariate analysis showed that there was a relationship between workload (P-value = 0.04) and length of service (P-value = 0.02) with work stress on nurses at IRNA surgical Dr. M. Djamil Padang in 2022. It is hoped that the agency should hold training on stress management for nurses as well as activities such as outbound, study tours, spiritual activities, and doing physical activities together such as gymnastics for refreshment and refreshing for nurses.
FAKTOR-FAKTOR YANG MEMPENGARUHI INTENTION TO USE GUNA MENINGKATAN PANGSA PASAR LAYANAN VIDEO STREAMING
Authors: SYALOMIA NAFTALI , SUTRISNO NUNO 
Published: August 2024

The purpose of this study was to determine the effect of Perceived Ease of Use, Perceived Usefulness, Ritualized use and Instrumental Use toward Intention to Use on Netflix users in DKI Jakarta. This research used research method through a survey. Data analysis was carried out quantitatively and used a causal research design. Sample collected using Non-Probability Sampling with purposive sampling technique. The total sample used in this study was 147 respondents and will be processed using SPSS 25 software. The data analysis technique used in this study is multiple linear regression. The results of this study has shown that Perceived Ease of Use, Perceived Usefulness, Ritualized use and Instrumental Use have an influence on Intention to Use. This research is expected to provide input or suggestions to video streaming service companies, especially Netflix, which is the object of this research, is to be able to increasing the market share of video streaming companies in Indonesia.
THE INFLUENCE OF BRAND IDENTITY TOWARDS BRAND LOYALTY AND RESILIENCE TO NEGATIVE INFORMATION ON HONDA IN JAKARTA
Authors: UTOMO ALEXANDER PRIMA , PRASASTYO KLEMENS WEDANAJI 
Published: August 2024

This research aims to determine the influence of service quality, price and restaurant environment variables on customer loyalty through customer satisfaction variables. The object of this research is the China restaurant "Din Tai Fung" in DKI Jakarta. Sample identification was carried out using a purposive sampling met by determining nine sampling criteria, so that a total of 274 respondents were obtained with 257 data responden who met the criteria and could be used as research samples. This research uses a multivariate analysis model test the influence of each variable. The research results show that the variables of service quality, price a restaurant environment influence variations in customer loyalty through variations in customer satisfaction.
DIGITAL SPACE AS AN ENVIRONMENT FOR THE INTEGRATION OF ECONOMIC SYSTEMS IN A DIGITAL ECONOMY
Authors: НАПОЛЬСКИХ Д.Л. 
Published: August 2024

Цифровое пространство рассматривается как самостоятельное сложное явление, являющееся частью многослойного пространства территории, также включающего в себя физическое, экономическое, административное и социальное пространства. Особое внимание в рамках исследования уделено проблеме интеграции экономических систем в цифровом пространстве в контексте проблем территориальной кластеризации производства. Обобщены теоретические подходы к экономической сущности и содержанию категории «пространство», выделены пять типов пространства и относящиеся к ним элементы. Даны определения и определены ключевые функции пяти типов пространства территории: физического, социального, административного, экономического и цифрового. Выделены шесть иерархических уровней системы расселения в Российской Федерации и соответствующие им элементы административного пространства: поселенческий, районный, межрайонный, региональный, межрегиональный, национальный. Определены основные свойства цифрового пространства, выявлены следующие функции цифрового пространства: информационная, интегрирующая, координирующая, синхронизирующая, оптимизирующая и институциональная...
Digital space is considered as an independent complex phenomenon, which is part of the multilayered space of the territory, which also includes physical, economic, administrative and social spaces. Special attention in the framework of the study is paid to the problem of integration of economic systems in the digital space in the context of the problems of territorial clustering of production. Theoretical approaches to the economic essence and content of the category "space" are summarized, five types of space and related elements are identified. Definitions are given and the key functions of five types of territory space are defined: physical, social, administrative, economic and digital. There are six hierarchical levels of the settlement system in the Russian Federation and the corresponding elements of the administrative space: settlement, district, inter-district, regional, interregional, national. The main properties of the digital space are defined, the following functions of the digital space are revealed: informational, integrating, coordinating, synchronizing, optimizing and institutional. A conceptual model for the development of the digital space is proposed, and socio-economic systems functioning within various types of space are systematized. An innovative hypercluster model is proposed as a model for the integration of economic systems within the digital space of the territory.
CYBERSECURITY IN THE OIL AND GAS INDUSTRY: FOREIGN EXPERIENCE AND RECOMMENDATIONS TO RUSSIAN COMPANIES
Authors: КАМЧАРОВА Ю.А. , СЕМЕНОВ А.С. 
Published: August 2024

В современных условиях особое внимание привлекают увеличивающиеся в масштабах угрозы кибератаки на различные организации. Опасение вызывают повышение уровня сложности, изощренности и частоты таких инцидентов. На фоне глобального перехода на онлайн формы взаимодействия, цифровизации производственных процессов и организации удаленных форм труда опасность быть подвергнутым взлому систем возрастает в геометрической прогрессии. Современная практика цифровизации технологических процессов включает в себя использование IoT. Нефтегазовые и энергетические компании формируют единое цифровое пространство за счет интеграции оборудования, систем, ПО и таких технологий как цифровые двойники, цифровые месторождения и «умные» сети. Следует помнить, что внедрение высоких технологий бросает новые вызовы, и отрасль IoT остается одной из самых проблемных с точки зрения кибербезопасности. В рамках работы было проведено исследование корпоративных систем обеспечения информационной безопасности на предприятиях нефтегазового сектора зарубежных стран, анализ лучших зарубежных практик и методов оценки эффективности системы информационной безопасности в зарубежных компаниях нефтегазового сектора.
In modern conditions, special attention is drawn to the increasing threat of cyber-attacks on various organizations. The increasing level of complexity, sophistication and frequency of such incidents are of concern. Against the background of the global transition to online forms of interaction, digitalization of production processes and the organization of remote forms of work, the danger of being subjected to hacking systems increases exponentially. Modern practice of digitalization of technological processes includes the use of IoT. Oil and gas and energy companies are forming a single digital space through the integration of equipment, systems, software and technologies like digital twins, digital fields and «smart» grids. It should be remembered that the introduction of high technologies poses new challenges, and the IoT industry remains one of the most problematic from the point of view of cybersecurity. This article shows the results of a cross-disciplinary study of corporate information security systems, an analysis of the best foreign practices and methods for evaluating the effectiveness of the information security system of the companies of the foreign oil and gas sector.
STATE REGULATION OF NATURAL MONOPOLIES IN THE RUSSIAN FEDERATION
Authors: ХАВАНОВА Н.В. , ДАНИЛОВА  В.А. , ЛИТВИНОВА Е.В. , ГАСТИЛО Л.В. , МЕДВЕДЕВ С.П. 
Published: August 2024

В современном мире такое явление, как естественные монополии, представляется весьма распространенным, и Россия не является исключением. Статья посвящена изучению феномену естественных монополий. На данный момент основная доля ВВП России создаётся именно субъектами естественных монополий. Они контролируют основные сферы, которые требуются для полноценного развития экономики. Исследование особенности темы взаимодействия государства и естественных монополий необходимо для успешного контроля. Этим фактором объясняется актуальность и важность данной темы на сегодняшний день.
In the modern world, the phenomenon of natural monopolies seems to be very common, and Russia is no exception. The article is devoted to the study of the phenomenon of natural monopolies. At the moment, the main share of Russia’s GDP is created by natural monopolies. They control the main areas that are required for the full development of the economy. Research into the specifics of the topic of interaction between the state and natural monopolies is necessary for successful control. This factor explains the relevance and importance of this topic today.
SOME ASPECTS OF RUSSIA'S ECONOMIC POLICY IN THE FIELD OF IMPORT SUBSTITUTION
Authors: ЯНДИЕВА М.С. , ЦУРОВ М.Д. , ТАРШХОЕВА М.М. , АЛБАГАЧИЕВА А.А. 
Published: August 2024

В данной статье представлен обзор российской политики импортозамещения и проанализированы ее достижения на сегодняшний день. Проанализированы основные задачи российской политики импортозамещения обеспечение технической и экономической безопасности производств, повышение технической оснащенности предприятий, развитие человеческого капитала, особенно в отраслях, связанных с импортозависимыми производствами, развитие вспомогательной инфраструктуры, создание нормативно-правовой базы и контроль при разработке программ и планов реализации соответствующих проектов.
This article provides an overview of the Russian import substitution policy and analyzes its achievements to date. The main tasks of the Russian import substitution policy are analyzed ensuring the technical and economic security of production facilities, improving the technical equipment of enterprises, developing human capital, especially in industries related to import-dependent industries, developing auxiliary infrastructure, creating a regulatory framework and monitoring the development of programs and plans for the implementation of relevant projects.
ON THE USE OF FOREIGN EXPERIENCE IN THE ORGANIZATION OF MORTGAGE SECURITIZATION IN RUSSIA
Authors: ЯКУШКИНА О.С. , НАЗАРОВА Л.Н. 
Published: August 2024

В статье рассмотрены основные модели ипотечного кредитования, дан обзор рынков ипотечной секьюритизации в США, Европе и России, проведено сравнениеа ипотечных агентств США и России. Раскрыты возможности использования зарубежного опыта организации ипотечной секьюритизации и предложены направления совершенствования данного процесса.
The article examines the main models of mortgage lending, provides an overview of the mortgage securitization markets in the United States, Europe and Russia, and compares mortgage agencies in the United States and Russia. The possibilities of using foreign experience in the organization of mortgage securitization are revealed and directions for improving this process are proposed.
THE STATE'S POLICY AIMED AT COMBATING CORRUPTION, ITS MOST EFFECTIVE SIDES
Authors: КОРОТАЕВА Т.В. , БЕЛОУСОВ А.С. 
Published: August 2024

Вопросы, связанные с коррупцией, являются важными для развития всего государства в целом и качества жизни каждого его гражданина. Данная статья содержит в себе анализ политики государства, направленной на борьбу с коррупционными правонарушениями, выявлению наиболее ее действенных сторон. Значимость решения данной проблемы подтверждается тем, что непосредственное участие в вопросах, связанных с коррупцией, принимает Президент России, Федеральное Собрание и Правительство РФ. Государственная антикоррупционная политика утверждается на высшем государственном уровне и разрабатывается на основе всестороннего анализа проблемы коррупции в стране.
Issues related to corruption are important for the development of the entire state as a whole and the quality of life of each of its citizens. This article contains an analysis of the state's policy aimed at combating corruption offenses, identifying its most effective sides. The importance of solving this problem is confirmed by the fact that the President of Russia, the Federal Assembly and the Government of the Russian Federation are directly involved in issues related to corruption. The State anti-corruption policy is approved at the highest state level and is developed on the basis of a comprehensive analysis of the problem of corruption in the country.