bluuebunny/crossref_metadata_2025_split huggingface dataset:
Asset Management, Life Extension and Fitness for Service in the High Pressure Industry
Authors: Peters Daniel T. , Haley Kevin M. 
Published: August 2013

Long term asset management is a key issue in the high pressure industry, but only limited and somewhat fragmented guidelines exist in the form of various “New-Construction” Design Codes and Standards. The high pressure industry is a niche industry and many applications are not covered completely by existing codes and standards. The paper will cover an overview of various ASME and API documents and provide an overall methodology for the implementation of an effective and logical asset management protocol including Fitness for Service guidelines which can be referenced in lieu of a comprehensive document being available.
ASME discontinued publication and distribution of the High Pressure Systems Standard (HPS-2003) [6] in September 2009. One of the most common uses for this document was the section on vessel requalification. The paper here will discuss the application of this requalification methodology, and its use in an overall high pressure asset management plan.
API 510 [5] and the National Board Inspection Code (NBIC) [13] cover the in-service inspection, repair, alteration, and rerating activities for pressure vessels-including vessels constructed and approved as jurisdictional special based upon jurisdiction acceptance of particular design, fabrication, inspection, testing, and installation. However those documents reference most of the technical requirements in the ASME construction codes for design, welding, NDE, and materials as being applicable for in-service pressure vessels. Also, API 510 and NBIC recognize FFS assessments for evaluating the structural integrity of in-service damage of pressure-containing components. This paper will discuss the use of those construction codes for use in a Fitness for Service assessment and the development of a comprehensive strategy for long term asset management using these guidance documents in conjunction with the ASME/API Inspection Planning guidelines.
Steam Line Integrity Analyses for LTO: Enhancing Credibility With Comprehensive Measurement
Authors: Rothenhöfer Horst , Manke Andreas 
Published: August 2013

The safety relevant components of nuclear power plant Neckarwestheim 1 — in service since 1976 — have been reviewed and updated for long-term operation (LTO). The actions included hardware retrofits as well as updates of analysis according to the latest state of the scientific and technical knowledge. For large piping such as the steam lines, the established pipes have been retained while the supports have been optimized. All shock absorbers (snubbers) including corresponding inertia have been eliminated resulting in a defined guidance and statically defined displacements.
The integrity analyses for the optimized steam lines, including break preclusion, have been validated successfully with comprehensive measurements. The verification has delivered an extra high level of credibility, exceeding the “standard” requirements to achieve fitness for service in long-term operation.
Measurement and validation, which are the main focus of this paper, range from monitoring of service loads to the static and dynamic measurements of pressure, local temperatures and displacements during initial start-up after implementation of the design modifications. The proper function of supports has been proved and the quality of the simulation models has been confirmed.
Some expected and some unexpected dynamic events have been detected during blow-down tests. It was demonstrated that the amplitudes of all dynamic loads stay within limits.
The validation of analyses with comprehensive measurement has been an important proof of quality and delivered the redundancy required for the integrity of a nuclear power plant in service, enhancing the high level of safety even more.
Stress Analysis of the Bipartite Overlapping Expansion Joints of the Containment Penetration: Angra 2
Authors: Suanno Rodolfo L. M. , Maneschy José Eduardo de Almeida , Francioni Milton Kronenberg 
Published: August 2013

During the 2010 outage of Angra 2 Power Plant the expansion joints of the containment penetration JMK05D0201 (LCQ50) which belongs to the blowndown system were found very distorted as shown in Fig. 1. The cause was an inadvertent over pressurization made during monthly tests to verify the set pressure. In order to leave the damaged expansion joint installed during one cycle, Eletronuclear conducted an elastic-plastic analysis which has demonstrated the joint could be in the position up to the next Angra 2 outage, in March 2012.
Considering that the option to replace the damaged expansion joint by another one is extremely complex, Eletronuclear decided to keep it in place and cover it by an expansion joint designed to resist all loads predicted in the original design specification. This new design is a two-sided (bipartite) bellows with longitudinal field welds.
This paper presents the fatigue and stress analysis of the bipartite overlapping expansion joints considering the loads defined in the design specification. Based on the results obtained, fatigue is not a concern and stress/strains are kept under acceptable values for all loading conditions. In addition, it also was demonstrated that the original design of the blowdown system was not impacted by the proposed design of the bipartite joint.
A system for EPID‐based real‐time treatment delivery verification during dynamic IMRT treatment
Authors: Fuangrod Todsaporn , Woodruff Henry C. , van Uytven Eric , McCurdy Boyd M. C. , Kuncic Zdenka , O'Connor Daryl J. , Greer Peter B. 
Published: August 2013

Purpose:To design and develop a real‐time electronic portal imaging device (EPID)‐based delivery verification system for dynamic intensity modulated radiation therapy (IMRT) which enables detection of gross treatment delivery errors before delivery of substantial radiation to the patient.Methods:The system utilizes a comprehensive physics‐based model to generate a series of predicted transit EPID image frames as a reference dataset and compares these to measured EPID frames acquired during treatment. The two datasets are using MLC aperture comparison and cumulative signal checking techniques. The system operation in real‐time was simulated offline using previously acquired images for 19 IMRT patient deliveries with both frame‐by‐frame comparison and cumulative frame comparison. Simulated error case studies were used to demonstrate the system sensitivity and performance.Results:The accuracy of the synchronization method was shown to agree within two control points which corresponds to approximately ∼1% of the total MU to be delivered for dynamic IMRT. The system achieved mean real‐time gamma results for frame‐by‐frame analysis of 86.6% and 89.0% for 3%, 3 mm and 4%, 4 mm criteria, respectively, and 97.9% and 98.6% for cumulative gamma analysis. The system can detect a 10% MU error using 3%, 3 mm criteria within approximately 10 s. The EPID‐based real‐time delivery verification system successfully detected simulated gross errors introduced into patient plan deliveries in near real‐time (within 0.1 s).Conclusions:A real‐time radiation delivery verification system for dynamic IMRT has been demonstrated that is designed to prevent major mistreatments in modern radiation therapy.
Draft Genome Sequence of
d
-Branched-Chain Amino Acid Producer Lactobacillus otakiensis JCM 15040
T
, Isolated from a Traditional Japanese Pickle
Authors: Doi Katsumi , Mori Kazuki , Mutaguchi Yuta , Tashiro Kosuke , Fujino Yasuhiro , Ohmori Taketo , Kuhara Satoru , Ohshima Toshihisa 
Published: August 2013

ABSTRACT

Lactobacillus otakiensis
strain JCM 15040
T
was isolated from an unsalted pickling solution used in the production of sunki, a traditional Japanese pickle. Here, we prepared a draft genome sequence for this strain consisting of 40 contigs containing a total of 2,347,132 bp, 2,310 predicted coding sequences, and a G+C content of 42.4%.
Complete Genome Sequences of Novel Reassortant H1N2 Swine Influenza Viruses Isolated from Pigs in the Republic of Korea
Authors: Pascua Philippe Noriel Q. , Lim Gyo-Jin , Kwon Hyeok-il , Kim Young-il , Kim Eun-Ha , Park Su-Jin , Kim Se Mi , Decano Arun G. , Choi Eun-Ji , Jeon Hae-Young , Kim Chul-Joong , Choi Young-Ki 
Published: August 2013

ABSTRACT
Novel reassortant swine H1N2 influenza viruses were isolated from pigs in a commercial slaughterhouse in the Republic of Korea. Genome sequence analyses revealed that these isolates contain segments from Eurasian avian-like swine (hemagglutinin [HA]), Korean swine H1N2 (neuraminidase [NA]), and North American H3N2pM-like (remaining genes) viruses. Further characterization is needed to gauge the potential threats of these viruses to public health.
Genome Sequence of Staphylococcus massiliensis Strain S46, Isolated from the Surface of Healthy Human Skin
Authors: Srivastav Rajpal , Singh Ajit , Jangir Pramod Kumar , Kumari Chanchal , Muduli Suchismita , Sharma Rakesh 
Published: August 2013

ABSTRACT

Staphylococcus massiliensis
strain S46 was isolated from the surface of healthy human skin. Here, we report the draft genome sequence of
S. massiliensis
S46 (2,447,110 bp, with a G+C content of 36.3%).
Complete Genome Sequence of Porcine Epidemic Diarrhea Virus Strain USA/Colorado/2013 from the United States
Authors: Marthaler Douglas , Jiang Yin , Otterson Tracy , Goyal Sagar , Rossow Kurt , Collins James 
Published: August 2013

ABSTRACT
Porcine epidemic diarrhea virus (PEDV) is newly emerging in the United States. PEDV strain USA/Colorado/2013 (CO/13) was obtained from a 7-day-old piglet with severe diarrhea, and the complete genome was sequenced to further study the PEDV outbreak in the United States.
Identification of a Novel Circular DNA Virus in New Zealand Fur Seal (
Arctocephalus forsteri
) Fecal Matter
Authors: Sikorski Alyssa , Dayaram Anisha , Varsani Arvind 
Published: August 2013

ABSTRACT

Fur seal feces-associated circular DNA virus (FSfaCV) is a novel virus isolated from the fecal matter of New Zealand fur seals. FSfaCV has two main open reading frames in its 2,925-nucleotide (nt) genome. The replication-associated protein (Rep) of FSfaCV has similarity to Rep-like sequences in the
Giardia intestinalis
genome.
Discovery of Sclerotinia sclerotiorum Hypovirulence-Associated Virus-1 in Urban River Sediments of Heathcote and Styx Rivers in Christchurch City, New Zealand
Authors: Kraberger Simona , Stainton Daisy , Dayaram Anisha , Zawar-Reza Peyman , Gomez Christopher , Harding Jon S. , Varsani Arvind 
Published: August 2013

ABSTRACT

In samples of benthic and bank river sediments of two urban rivers in Christchurch city (New Zealand), we identified and recovered isolates of
Sclerotinia sclerotiorum
hypovirulence-associated virus-1 (SsHADV-1), a fungus-infecting circular single-stranded DNA virus. This is the first report of SsHADV-1 outside of China and in environmental samples.
Whole-Genome Sequence of the Purple Photosynthetic Bacterium Rhodovulum sulfidophilum Strain W4
Authors: Masuda Shinji , Hori Koichi , Maruyama Fumito , Ren Shukun , Sugimoto Saori , Yamamoto Nozomi , Mori Hiroshi , Yamada Takuji , Sato Shusei , Tabata Satoshi , Ohta Hiroyuki , Kurokawa Ken 
Published: August 2013

ABSTRACT

We report the draft genome sequence of the purple photosynthetic bacterium
Rhodovulum sulfidophilum
. The photosynthesis gene cluster comprises two segments—a unique feature among photosynthesis gene clusters of purple bacteria. The genome information will be useful for further analysis of bacterial photosynthesis.
Draft Genome Sequence of Streptomyces rapamycinicus Strain NRRL 5491, the Producer of the Immunosuppressant Rapamycin
Authors: Baranasic Damir , Gacesa Ranko , Starcevic Antonio , Zucko Jurica , Blažič Marko , Horvat Marinka , Gjuračić Krešimir , Fujs Štefan , Hranueli Daslav , Kosec Gregor , Cullum John , Petković Hrvoje 
Published: August 2013

ABSTRACT

Streptomyces rapamycinicus
strain NRRL 5491 produces the important drug rapamycin. It has a large genome of 12.7 Mb, of which over 3 Mb consists of 48 secondary metabolite biosynthesis clusters.
Draft Genome Sequence of Pseudomonas plecoglossicida Strain NB2011, the Causative Agent of White Nodules in Large Yellow Croaker (Larimichthys crocea)
Authors: Mao Zhijuan , Li Meifang , Chen Jigang 
Published: August 2013

ABSTRACTWe describe the draft genome sequence ofPseudomonas plecoglossicidastrain NB2011, the causative agent of white nodules in cultured large yellow croaker (Larimichthys crocea) in China. The draft genome sequence of the bacterium consists of 5.41 million bp, with a G+C content of 62.8%. A total of 4,952 genes were identified.
Draft Genome Sequence of Strain SA_ST125_MupR of Methicillin-Resistant Staphylococcus aureus ST125, a Major Clone in Spain
Authors: Barrado Laura , Viedma Esther , Vindel Ana , Otero Joaquín R. , Chaves Fernando 
Published: August 2013

ABSTRACT

Here, we report the draft genome sequence of a methicillin-resistant
Staphylococcus aureus
(MRSA) strain with high-level mupirocin resistance (SA_ST125_MupR), isolated from a patient with recurrent bacteremia. This strain belonged to sequence type ST125, which was responsible for more than 50% of the health care-associated infections caused by MRSA in Spain.
Draft Genome Sequence of the Fast-Growing Marine Bacterium Vibrio natriegens Strain ATCC 14048
Authors: Wang Zheng , Lin Baochuan , Hervey W. Judson , Vora Gary J. 
Published: August 2013

ABSTRACT

Vibrio natriegens
bacteria are Gram-negative aquatic microorganisms that are found primarily in coastal seawater and sediments and are perhaps best known for their high growth rates (generation time of <10 min). In this study, we report the first sequenced genome of this species, that of the type strain
Vibrio natriegens
ATCC 14048, a salt marsh mud isolate from Sapelo Island, GA.
Whole-Genome Sequence of a Novel Species, Mycobacterium yongonense DSM 45126
T
Authors: Kim Byoung-Jun , Kim Bo-Ram , Lee So-Young , Seok Seung-Hyeok , Kook Yoon-Hoh , Kim Bum-Joon 
Published: August 2013

ABSTRACT

Here, we report the complete genome sequence of
Mycobacterium yongonense
DSM 45126
T
, genetically closely related to the INT5 genotype of
M. intracellulare
.
London 2012 Paralympic swimming: passive drag and the classification system
Authors: Oh Yim-Taek , Burkett Brendan , Osborough Conor , Formosa Danielle , Payton Carl 
Published: August 2013

BackgroundThe key difference between the Olympic and Paralympic Games is the use of classification systems within Paralympic sports to provide a fair competition for athletes with a range of physical disabilities. In 2009, the International Paralympic Committee mandated the development of new, evidence-based classification systems. This study aims to assess objectively the swimming classification system by determining the relationship between passive drag and level of swimming-specific impairment, as defined by the current swimming class.MethodsData were collected on participants at the London 2012 Paralympic Games. The passive drag force of 113 swimmers (classes 3–14) was measured using an electro-mechanical towing device and load cell. Swimmers were towed on the surface of a swimming pool at 1.5 m/s while holding their most streamlined position.ResultsPassive drag ranged from 24.9 to 82.8 N; the normalised drag (drag/mass) ranged from 0.45 to 1.86 N/kg. Significant negative associations were found between drag and the swimming class (τ=−0.41, p<0.01) and normalised drag and the swimming class (τ=−0.60, p<0.01). The mean difference in drag between adjacent classes was inconsistent, ranging from 0 N (6 vs 7) to 11.9 N (5 vs 6). Reciprocal Ponderal Index (a measure of slenderness) correlated moderately with normalised drag (rP=−0.40, p<0.01).ConclusionsAlthough swimmers with the lowest swimming class experienced the highest passive drag and vice versa, the inconsistent difference in mean passive drag between adjacent classes indicates that the current classification system does not always differentiate clearly between swimming groups.
Public views on the donation and use of human biological samples in biomedical research: a mixed methods study
Authors: Lewis Celine , Clotworthy Margaret , Hilton Shona , Magee Caroline , Robertson Mark J , Stubbins Lesley J , Corfield Julie 
Published: August 2013

ObjectiveA mixed methods study exploring the UK general public's willingness to donate human biosamples (HBSs) for biomedical research.SettingCross-sectional focus groups followed by an online survey.ParticipantsTwelve focus groups (81 participants) selectively sampled to reflect a range of demographic groups; 1110 survey responders recruited through a stratified sampling method with quotas set on sex, age, geographical location, socioeconomic group and ethnicity.Main outcome measures(1) Identify participants’ willingness to donate HBSs for biomedical research, (2) explore acceptability towards donating different types of HBSs in various settings and (3) explore preferences regarding use and access to HBSs.Results87% of survey participants thought donation of HBSs was important and 75% wanted to be asked to donate in general. Responders who self-reported having some or good knowledge of the medical research process were significantly more likely to want to donate (p<0.001). Reasons why focus group participants saw donation as important included: it was a good way of reciprocating for the medical treatment received; it was an important way of developing drugs and treatments; residual tissue would otherwise go to waste and they or their family members might benefit. The most controversial types of HBSs to donate included: brain post mortem (29% would donate), eyes post mortem (35%), embryos (44%), spare eggs (48%) and sperm (58%). Regarding the use of samples, there were concerns over animal research (34%), research conducted outside the UK (35%), and research conducted by pharmaceutical companies (56%), although education and discussion were found to alleviate such concerns.ConclusionsThere is a high level of public support and willingness to donate HBSs for biomedical research. Underlying concerns exist regarding the use of certain types of HBSs and conditions under which they are used. Improved education and more controlled forms of consent for sensitive samples may mitigate such concerns.
Quality and safety in transitional care of the elderly: the study protocol of a case study research design (phase 1)
Authors: Aase Karina , Laugaland Kristin Alstveit , Dyrstad Dagrunn Nåden , Storm Marianne 
Published: August 2013

IntroductionAlthough international studies have documented that patients’ transitions between care providers are associated with the risk of adverse events and uncoordinated care, research directed towards the quality and safety of transitional care between primary and secondary health and care services, especially for the elderly receiving care from multiple healthcare providers due to complex health problems, is lacking. This study investigates how different aspects of transitional care can explain the quality and safety of elderly healthcare services in Norway. The overall aim of the study was to explore different aspects of transitional care of the elderly, in different contexts and how they might explain the quality and safety of care.Methods and analysisThe study applies a case study design. Two cases are chosen: one city-based hospital and one rural hospital with associated nursing homes and home-based nursing services. Admission and discharge to/from hospital to/from nursing homes or home-based nursing services constitute the main focal areas of the study, including the patient, next-of-kin and the professional perspective. The qualitative methods employed include participant observation, individual interviews and document analysis. To ensure trustworthiness in the data analysis, we will apply analyst triangulation and member checks. A total impression of the data material will first be created in a systematic text condensation approach. Second, the qualitative data analysis will involve in-depth analyses of two specific themes: the risk perspective and the patient perspective in transitional care.Ethics and disseminationThe study is approved by the Norwegian Regional Committees for Medical and Health Research Ethics. The study is based on informed written consent, and informants can withdraw from the study at any point in time. Interview and observation data material will be managed confidentially.ResultsIt will be disseminated at research conferences, in peer-reviewed journals and through public presentations to people outside the academic community.
A Protocol for the Pharmacokinetics of Enteric Coated Mycophenolate Sodium in Lupus Nephritis (POEMSLUN): an open-label, randomised controlled trial
Authors: Ranganathan Dwarakanathan , John George T , Healy Helen , Roberts Matthew J , Fassett Robert G , Lipman Jeffrey , Kubler Paul , Ungerer Jacobus , McWhinney Brett C , Lim Aaron , Purvey Megan , Reyaldeen Reza , Roberts Jason A 
Published: August 2013

IntroductionMycophenolate sodium, an enteric-coated tablet (EC-MPS), is as effective and safe as mycophenolate mofetil (MMF) in preventing transplant rejection. EC-MPS and MMF improve the outcome of severe lupus nephritis (LN) and have fewer side effects than pulsed intravenous cyclophosphamide. Blood concentrations of mycophenolic acid (MPA), the active metabolite of EC-MPS, vary between participants despite fixed dosing. Interpatient variability has been studied in transplantation, but not well documented in LN. The relationship between MPA concentration and its clinical effect on LN has not been described.Methods and analysisThis is a prospective, open-label, randomised controlled trial. –32 participants with LN who meet the inclusion and exclusion criteria will be randomised into two groups: one receiving a fixed dose of EC-MPS and the second, a dosing regimen that is titrated with therapeutic drug monitoring. Included participants will have blood sampled over a period of 8–12 h on three different occasions. Pharmacokinetic parameters will be calculated using non-compartmental methods.Ethics and disseminationThe Human Research and Ethics Committee of the Royal Brisbane Women's Hospital have approved this study. The study is registered with Australian and New Zealand Clinical Trials Registry—ACTRN12611000798965 We planned to present the de-identified information at conferences and publish the results in medical journals.Trial RegistrationACTRN12611000798965