bluuebunny/crossref_metadata_2025_split huggingface dataset:
The need to belong and self‐disclosure in positive word‐of‐mouth behaviours: The moderating effect of self–brand connection
Authors: Sicilia Maria , Delgado‐Ballester Elena , Palazon Mariola 
Published: October 2015

AbstractWord of mouth (WOM) is an important information source for consumers. Nowadays, many consumers promote and spread the word about their preferred brands, thereby influencing others' attitudes and behaviours. Based on a social behaviour perspective and the need to belong theory, this research proposes that the individual's need to belong and the individual's level of self‐disclosure increase their probability of engaging in positive WOM behaviour. The moderating role of self–brand connection in the aforementioned relationships is also analysed. In the study conducted, users of a well‐known baby food brand (n = 851) were surveyed. The results revealed that the individuals' need to belong fostered the desire to talk to others about their preferred brand. A negative moderating effect of self–brand connection was also observed. As the connection with the brand is lower, the motivation to engage in positive WOM will be more related to personal characteristics, such as their need to belong and level of self‐disclosure. Copyright © 2015 John Wiley & Sons, Ltd.
Specificity of Lipoprotein Chaperones for the Characteristic Lipidated Structural Motifs of their Cognate Lipoproteins
Authors: Mejuch Tom , van Hattum Hilde , Triola Gemma , Jaiswal Mamta , Waldmann Herbert 
Published: October 2015

AbstractLipoprotein‐binding chaperones mediate intracellular transport of lipidated proteins and determine their proper localisation and functioning. Understanding of the exact structural parameters that determine recognition and transport by different chaperones is of major interest. We have synthesised several lipid‐modified peptides, representative of different lipoprotein classes, and have investigated their binding to the relevant chaperones PDEδ, UNC119a, UNC119b, and galectins‐1 and ‐3. Our results demonstrate that PDEδ recognises S‐isoprenylated C‐terminal peptidic structures but not N‐myristoylated peptides. In contrast, UNC119 proteins bind only mono‐N‐myristoylated, but do not recognise doubly lipidated and S‐isoprenylated peptides at the C terminus. For galectins‐1 and ‐3, neither binding to N‐acylated, nor to C‐terminally prenylated peptides could be determined. These results shed light on the specificity of the chaperone‐mediated cellular lipoprotein transport systems.
Matrix‐based three‐dimensional culture of buffalo mammary epithelial cells showed higher induction of genes related to milk protein and fatty acid metabolism
Authors: Shandilya Umesh K. , Sharma Ankita , Sodhi Monika , Kapila Neha , Kishore Amit , Mohanty Ashok , Kataria Ranjit , Malakar Dhruva , Mukesh Manishi 
Published: October 2015

AbstractDemanding transcriptomic studies in livestock animal species could be replaced by good in vitro models mimicking the function of mammary gland. Mammary epithelial cells (MEC) are the functional unit of the mammary gland. Extracellular matrix is known to be a key factor providing normal homeostasis in three‐dimensional (3D) environment as important signals are lost when cells are cultured in two‐dimensional (2D) environment. The aims of this study were to establish a buffalo mammary epithelial cells (BMECs) in 3D culture using extracellular matrix and to determine whether such a 3D culture model has different expression pattern than 2D counterpart. The purified MEC generated after several passages were used to establish 3D culture using Geltrex matrix. The expression of milk casein genes viz., alpha S1‐casein (CSN1S1), alpha S2‐casein (CSN1S2), beta‐casein (CSN2), kappa‐casein (CSN3); and fatty acid metabolism genes viz., butyrophilin (BTN1A1), glycerol‐3‐phosphate acyltransferase (GPAM), fatty acid‐binding protein 3 (FABP3), and stearoyl‐CoA desaturase (SCD) was assessed in 3D culture in comparison to traditional monolayer culture using qRT‐PCR. Notable morphological differences were observed for BMECs grown in 3D culture in comparison to 2D culture. Morphologically, epithelial structures grown in Geltrex matrix (3D) environment showed enhanced functional differentiation in comparison to 2D culture. In 3D culture, lumen and dome‐like structures were formed by day 5, whereas polarized acinus‐like structure were formed within 15 days of culturing. The expression data showed higher mRNA induction of milk casein and fatty acid metabolism genes in 10‐day‐old 3D BMECs culture in comparison to 2D monolayer culture. The result suggests that 3D organization of epithelial cells has favorable effect on induction of milk and fatty acid metabolism‐related genes. Therefore, matrix‐based 3D culture of MEC that recapitulate the structural and functional context of normal tissues could provide a better in vitro model to understand the mammary gland functioning of buffaloes.
Unwinding DNA and RNA with Synthetic Complexes: On the Way to Artificial Helicases
Authors: Gasiorek Martin , Schneider Hans‐Jörg 
Published: October 2015

AbstractSynthetic helicases can be designed on the basis of ligands that bind more strongly to single‐stranded nucleic acids than to double‐stranded nucleic acids. This can be achieved with ligands containing phenyl groups, which intercalate into single strands, but due to their small size not into double strands. Moreover, two phenyl rings are combined with a distance that allows bis‐intercalation with only single strands and not double strands. In this respect, such ligands also mimic single‐strand binding (SSB) proteins. Exploration with more than 23 ligands, mostly newly synthesised, shows that the distance between the phenyl rings and between those and the linker influence the DNA unwinding efficiency, which can reach a melting point decrease of almost ΔTm=50 °C at much lower concentrations than that with any other known artificial helicases. Conformational pre‐organisation of the ligand plays a decisive role in optimal efficiency. Substituents at the phenyl rings have a large effect, and increase, for example, in the order of H<F<Cl<Br, which illustrates the strong role of dispersive interactions in intercalation. Studies with homopolymers revealed significant selectivity: for example, with a ligand concentration of 40 μM at 35 °C, only GC double strands melt (ΔTm=48 °C), whereas the AT strand remains untouched, and with poly(rA)–poly(rU) as an RNA model one observes unfolding at 29 °C with a concentration of only 30 μM.
Aromatic Sulfonium Polyoxomolybdates: Solid‐State Photochromic Materials with Tunable Properties
Authors: Kumar Ashwani , Devi Manisha , Mamidi Narsimha , Gonsalves Kenneth E. , Pradeep Chullikkattil P. 
Published: October 2015

AbstractA new aromatic sulfonium counter‐ion motif for polyoxometalate (POM) clusters with potential for structural and electronic fine‐tuning has been designed. Its two derivatives 4‐hydroxyphenyl dimethylsulfonium triflate (HPDST) and 4‐(allyloxy)phenyl dimethylsulfonium triflate (APDST) exhibit ionic liquid behaviors under ambient conditions. HPDST and APDST are used to develop a series of aromatic sulfonium POM hybrids (HPDS/APDS)n[XMo12O40] (HPDS and APDS are the cations of HPDST and APDST, respectively; X=P or Si; n=3 or 4), which are tested for photochromic behavior. On exposure to UV light, these POM hybrids undergo color change from yellow to green/blue. The coloration kinetics half lives (t1/2) are less for APDS‐based hybrids than for HPDS‐based hybrids, suggesting that alkyl substitution on the phenolic group helps to fine‐tune the electron availability on the sulfonium moiety and hence to control the photochromic behavior of the POM hybrids. The t1/2 values of these hybrids are considerably lower than those of the reported aliphatic sulfonium POM hybrids. We have also demonstrated the application of photoreduced POM hybrids as catalysts for the reduction of 4‐nitrophenol to 4‐aminophenol.
The impact of stage, grade, and mucinous histology on the efficacy of systemic chemotherapy in adenocarcinomas of the appendix: Analysis of the National Cancer Data Base
Authors: Asare Elliot A. , Compton Carolyn C. , Hanna Nader N. , Kosinski Lauren A. , Washington Mary Kay , Kakar Sanjay , Weiser Martin R. , Overman Michael J. 
Published: October 2015

BACKGROUNDAdenocarcinomas of the appendix represent a heterogeneous disease depending on the presence of mucinous histology, histologic grade, and stage. In the current study, the authors sought to explore the interplay of these factors with systemic chemotherapy in a large population data set.METHODSPatients in the National Cancer Data Base (NCDB) who were diagnosed with mucinous, nonmucinous, and signet ring cell‐type appendiceal neoplasms from 1985 through 2006 were selected. Multivariable Cox proportional hazards regression models were developed.RESULTSA total of 11,871 patients met the inclusion criteria for the current study: 50.3% had mucinous neoplasms, 40.5% had nonmucinous neoplasms, and 9.2% had signet ring cell‐type neoplasms. The 5‐year overall survival (OS) stratified by grade was similar among patients with American Joint Committee on Cancer stage I to stage III disease but not for those with stage IV disease. The median OS for patients with stage IV mucinous and nonmucinous tumors was 6.4 years and 2.3 years, respectively, for those with well differentiated histology (P<.0001) and was 1.5 years and 0.8 years, respectively, for those with poorly differentiated histology (P<.0001). In multivariable modeling for stage I to III disease, adjuvant chemotherapy improved OS for both mucinous and nonmucinous histologies, with hazard ratios (HRs) of 0.78 (95% confidence interval [95% CI], 0.68‐0.89 [P = .0002]) and 0.83 (95% CI, 0.74‐0.94 [P = .002]), respectively. For patients with stage IV disease, systemic chemotherapy significantly improved OS for those with nonmucinous (HR, 0.72; 95% CI, 0.64‐0.82 [P<.0001]) but not mucinous (HR, 0.95; 95% CI, 0.86‐1.04 [P = .2) histologies, although this was grade‐dependent. The median OS for chemotherapy versus no chemotherapy was 6.4 years versus 6.5 years (P value not significant) for patients with mucinous, well‐differentiated tumors and 1.6 years versus 1.0 years (P = .0007) for patients with mucinous, poorly differentiated tumors.CONCLUSIONSAdjuvant chemotherapy demonstrated a significant OS benefit regardless of histology. However, for patients with stage IV disease, the benefit of systemic chemotherapy varied by tumor histology and grade, with patients with well‐differentiated, mucinous, appendiceal adenocarcinomas deriving no survival benefit from systemic chemotherapy. Cancer 2016;122:213–221. © 2015 American Cancer Society.
On the Energetics of Ions in Carbon and Gold Nanotubes
Authors: Mohammadzadeh Leila , Goduljan Aleksej , Juarez Fernanda , Quaino Paola , Santos Elizabeth , Schmickler Wolfgang 
Published: October 2015

AbstractWe investigate the insertion of halide and alkali atoms into narrow single‐walled carbon nanotubes with diameters <9 Å by density functional theory; both chiral and non‐chiral tubes are considered. The atoms are stored in the form of ions; the concomitant charge transfer affects the band structure and makes originally semiconducting tubes conducting. The electrostatic interaction between a charge and the walls of the tube is explicitly calculated. The insertion energies and the positions of the ions are determined by a competition between electrostatic energy and Pauli repulsion. For comparison, we consider ions in gold nanotubes. Alkali ions follow the same principles in gold as in carbon tubes, but chloride is specifically adsorbed inside gold tubes.
Atomic‐Level Mechanisms of Nucleation of Pure Liquid Metals during Rapid Cooling
Authors: Han Jiajia , Wang Cuiping , Liu Xingjun , Wang Yi , Liu Zi‐Kui , Jiang Jianzhong 
Published: October 2015

AbstractTo obtain a material with the desired performance, the atomic‐level mechanisms of nucleation from the liquid to solid phase must be understood. Although this transition has been investigated experimentally and theoretically, its atomic‐level mechanisms remain debatable. In this work, the nucleation mechanisms of pure Fe under rapid cooling conditions are investigated. The local atomic packing stability and liquid‐to‐solid transition‐energy pathways of Fe are studied using molecular dynamics simulations and first‐principle calculations. The results are expressed as functions of cluster size in units of amorphous clusters (ACs) and body‐centered cubic crystalline clusters (BCC‐CCs). We found the prototypes of ACs in supercooled liquids and successfully divided these ACs to three categories according to their transition‐energy pathways. The information obtained in this study could contribute to our current understanding of the crystallization of metallic melts during rapid cooling.
Photoluminescence and Photocatalytic Properties of Ag3PO4 Microcrystals: An Experimental and Theoretical Investigation
Authors: Botelho Gleice , Andres Juan , Gracia Lourdes , Matos Leandro S. , Longo Elson 
Published: October 2015

AbstractThe structural, morphological, and optical properties of Ag3PO4 microcrystals were systematically characterized by using a combination of theoretical calculations and experimental techniques. These microcrystals were synthesized by the microwave‐assisted hydrothermal (MAH) method. XRD, Rietveld refinements, and FTIR spectroscopy were employed to carry out a structural analysis; the morphologies of the microcrystals were examined by FEG‐SEM. First‐principles computational studies were used to calculate the geometries of bulk Ag3PO4 and its (010), (100), (001), (110), (101), (011), and (111) surfaces. A continuous decrease in the energy of the (100) surface led to a good agreement between the experimental and theoretical morphologies. Optical properties were investigated by UV/Vis spectroscopy and photoluminescence (PL) measurements, which revealed a maximum PL emission at λ=444 nm. The MAH‐synthesized sample exhibited good activity for the photocatalytic degradation of methyl orange dye under visible irradiation. The photocatalytic activity and PL behavior were correlated with the observed morphology.
Optimal transistor sizing for maximum yield in variation‐aware standard cell design
Authors: Abbas Zia , Olivieri Mauro 
Published: October 2015

SummaryProcess variability, in addition to wide temperature and supply voltage variation ranges, severely degrades the fabrication outcome (yield) of digital cells as for the fulfillment of performance specification bounds. This paper presents the application of mathematical optimization to the design of standard cells that are robust to process variations even in worst‐case operating conditions. The method attains the optimal sizing of individual transistors in the cell for maximizing the statistical yield referring to leakage power and propagation delay bounds, with local and global process variations specified by industrial process development kits (PDKs). The approach is demonstrated for a 40 nm low‐power standard threshold voltage Complementary Metal Oxide Semiconductor (CMOS) technology, for an intended operating temperature range [−40 °C, 125 °C] and supply voltage range [0.95 V, 1.05 V]. The reported optimization results show a yield improvement from an initial 50% to 99.9%, and Simulation Program with Integrated Circuit Emphasis (SPICE)‐level Monte Carlo analysis confirmed the estimated yield of the obtained circuits. Copyright © 2015 John Wiley & Sons, Ltd.
Electrocatalytic Study of Efficient Synthesized Graphene Nanosheets Incorporated with Pt Nanoparticles for Methanol Oxidation Reaction
Authors: Fahrul Radzi Hanifah Mohamad , Jaafar Juhana , Aziz Madzlan , Ismail A. F. , Thirmizir M. Z. A. , Othman M. H. D. , Rahman Mukhlis A. , Yusof N. 
Published: October 2015

AbstractGraphene nanosheets/Pt (GNS/Pt) nanocomposite was successfully fabricated via clean chemical reduction method. The nanocomposite was characterized by X‐ray diffraction, field emission scanning electron microscope and high resolution transmission electron microscope, which revealed that Pt nanoparticles were completely formed and homogenously distributed on the GNS. The electrochemical activities of the catalysts were investigated by cyclic voltammogram. The experimental results showed that GNS/Pt nanocomposites catalyst exhibited superior electrocatalytic activity for methanol oxidation. These results suggest that GNS/Pt nanocomposites would be a promising anode catalyst for DMFC.
Diamond as Advanced Material for Scanning Probe Microscopy Tips
Authors: Kranz Christine 
Published: October 2015

AbstractSynthetic diamond and conductive, doped forms of diamond are ideally suited materials for scanning probe microscopy tips due to their inherent physical, chemical, and mechanical properties. In particular for atomic force microscopy (AFM) and related techniques, which require a conductive tip in permanent contact to the sample surface, boron‐doped diamond (BDD) is an excellent material. Only few examples have so far been demonstrated using boron‐doped diamond microelectrodes as probes for scanning electrochemical microscopy (SEM) or AFM‐SECM. This review focuses on the state‐of‐the‐art using diamond‐coated SPM tips and conductive boron‐doped diamond as probe material discussing advantages and disadvantages.
Magneto‐switchable Electrodes and Electrochemical Systems
Authors: Katz Evgeny 
Published: October 2015

AbstractThis article is an overview of extensive research efforts in many laboratories in the last two decades in the area of magneto‐switchable electrochemical systems. Electrochemical reactions, including electrocatalytic and bioelectrocatalytic processes, have been reversibly activated and inhibited upon physical translocation and reorientation of different magnetic micro/nano‐species on electrode surfaces, particularly using magnetic micro/nanoparticles, adaptive nanowires and hybrid‐graphene sheets. These processes were triggered by repositioning an external magnet, thus resulting in changes in magnetic field at the electrode interfaces. Coupling of the magneto‐activated electrochemical systems with enzymatic reactions of various complexity allowed sophisticated bioelectronic devices for tunable biosensing, on‐demand power production, unconventional computing and other novel bioelectronic applications.
Characterisation of odour‐active compounds in cherimoya (Annona cherimola Mill.) fruit
Authors: Pino Jorge A. , Roncal Elda 
Published: October 2015

AbstractOptimized solid‐phase microextraction GC‐Olfactometry, and solvent‐assisted flavour evaporation, combined with aroma extract dilution analysis and with the determination of odour activity values by quantitative GC‐FID and GC‐MS were used to analyse volatile compounds from cherimoya fruit and to estimate the most odour‐active compounds. The analysis led to the identification of 92 compounds, 78 of them were positively identified. 18 odourants were considered as potentially odour‐active compounds and contribute to the typical cherimoya aroma, from which 3‐methylbutyl butanoate, α‐pinene, methyl 2‐methylbutanoate, butyl butanoate, and 3‐methylbutyl 3‐methylbutanoate were the most odour‐active compounds. HS‐SPME‐GC‐O has a great potential as fast and simple tool to control and assess aroma quality of cherimoya fruit. Copyright © 2015 John Wiley & Sons, Ltd.
Energy dissipative characteristic schemes for the diffusive Oldroyd‐B viscoelastic fluid
Authors: Lukáčová ‐ Medvid'ová Mária , Notsu Hirofumi , She Bangwei 
Published: October 2015

SummaryIn this paper, we propose new energy dissipative characteristic numerical methods for the approximation of diffusive Oldroyd‐B equations that are based either on the finite element or finite difference discretization. We prove energy stability of both schemes and illustrate their behavior on a series of numerical experiments. Using both the diffusive model and the logarithmic transformation of the elastic stress, we are able to obtain methods that converge as mesh parameter is refined. Copyright © 2015 John Wiley & Sons, Ltd.
Authenticity of raspberry flavor in food products using SPME‐chiral‐GC‐MS
Authors: Hansen Anne‐Mette S. , Frandsen Henrik L. , Fromberg Arvid 
Published: October 2015

AbstractA fast and simple method for authenticating raspberry flavors from food products was developed. The two enantiomers of the compound (E)‐α‐ionone from raspberry flavor were separated on a chiral gas chromatographic column. Based on the ratio of these two enantiomers, the naturalness of a raspberry flavor can be evaluated due to the fact that a natural flavor will consist almost exclusively of the R enantiomer, while a chemical synthesis of the same compound will result in a racemic mixture. Twenty‐seven food products containing raspberry flavors where investigated using SPME‐chiral‐GC‐MS. We found raspberry jam, dried raspberries, and sodas declared to contain natural aroma all contained almost only R‐(E)‐α‐ionone supporting the content of natural raspberry aroma. Six out of eight sweets tested did not indicate a content of natural aroma on the labeling which was in agreement with the almost equal distribution of the R and S isomer. Two products were labeled to contain natural raspberry flavors but were found to contain almost equal amounts of both enantiomers indicating a presence of synthetic raspberry flavors only. Additionally, two products that were labeled to contain both raspberry juice and flavor showed equal amounts of both enantiomers, indicating the presence of synthetic flavor.
Does the Size of the Effect of Adverse Events at High Ages on Daily‐Life Physical Functioning Depend on the Economic Conditions Around Birth?
Authors: Scholte Robert , van den Berg Gerard J. , Lindeboom Maarten , Deeg Dorly J.H. 
Published: October 2015

SummaryThis paper considers determinants of physical functional limitations in daily‐life activities at high ages. Specifically, we quantify the extent to which the impact of adverse life events on this outcome is larger in case of exposure to adverse economic conditions early in life. Adverse life events include bereavement, severe illness in the family, and the onset of chronic diseases. We use a longitudinal data set of individuals born in the first decades of the 20th century. The business cycle around birth is used as an indicator of economic conditions early in life. We find that the extent to which functional limitations suffer from the onset of chronic diseases is larger if the individual was born in a recession. The long‐run effect of economic conditions early in life on functional limitations at high ages runs primarily via this life event. Copyright © 2015 John Wiley & Sons, Ltd.
Anomalous drip in the Punkva caves (Moravian Karst): relevant implications for paleoclimatic proxies
Authors: Pracný Pavel , Faimon Jiří , Sracek Ondra , Kabelka Ludvík , Hebelka Jiří 
Published: October 2015

AbstractThe anomalous drip in the Punkva caves (Moravian Karst) shows specific hydrogeochemical properties such as low SIcalcite ~ 0.14 ± 0.11 (standard deviation), low mineralization (4.53 ± 0.42) × 10−3 mol l−1, and enhanced values of δ13C (−7.85 to −8.35‰ VPDB), Mg/Ca × 1000 ratio (45.7 ± 3.3), and Sr/Ca × 1000 ratio (0.65 ± 0.06). By these properties, the anomalous drip significantly differs from other regular drips in the same cave and other caves in the region. The study suggests that the anomalous drip properties are a consequence of prior calcite precipitation or/and water mixing along the water flow path. As the former processes are spatially controlled, the knowledge of dripwater flow path seems to be necessary for correct paleoclimatic/paleoenvironmental reconstructions. Copyright © 2015 John Wiley & Sons, Ltd.