bluuebunny/crossref_metadata_2025_split huggingface dataset:
1243 – Blood-borne Virus Testing In a Maximum Secure Psychiatric Hospital
Authors: Mortlock A.-M. , Mirowska L. , Garcia V. , Cohen A. , Sengupta S. 
Published: July 2013

IntroductionLittle evidence is available on the prevalence of hepatitis B virus (HBV), hepatitis C virus (HCV) and human immuno deficiency virus (HIV) in mentally ill populations. In April 2012 routine offering of testing for HBV, HCV and HIV of all individuals admitted at Broadmoor, a maximum secure psychiatric hospital, was introduced.ObjectivesTo elicit screening rates of, and to determine the prevalence of HBV, HCV and HIV in the inpatient population at Broadmoor Hospital.AimsTo critically assess the identification process of blood-borne viruses (BBV) in order to improve patient care.MethodsRetrospective data collection via the electronic patient record (EMIS) ascertained the proportion of the 198 inpatients offered screening and ultimately tested for HBV, HCV and HIV inclusive from April 1st 2012 to September 22nd 2012.ResultsThe proportion offered screening for HBV was 95% (189); for HCV was 94.9% (188) and for HIV was 92.9% (184). 129 patients were screened in each hepatitis group and 123 in the HIV group. Within the population of Broadmoor were three cases of HCV, one with HIV and zero with HBV.ConclusionsThis is a group at high risk for BBV infection and with a length of stay of up to five to six years it is important to identify those infected in order to instigate treatment and mitigate risk to both patients and staff. This study demonstrates rigorous screening for BBV is critical and will therefore necessarily impact on planning services for the future.
1244 – Bipolar Depression Rating Scale (bdrs): Psychometric Characteristics Of The Italian Validation
Authors: Bruschi A. , Calò S. , Camardese G. , Grandinetti P. , Palumbo C. , Pizi G. , Mandelli L. , Serretti A. , Berk M. , Di Sciascio G. , Janiri L. 
Published: July 2013

IntroductionThe scales for the assessment of depressive symptoms, translated and validated in Italian, lacks in the recognition of the psychopathological nuances of the disorder. The Bipolar Depression Rating Scale (BDRS) is a tool specifically built to reflect the characteristics of bipolar depression.MethodsScreening criteria:-aged 18–65 years-diagnosis of BD (DSM-IV-TR) (125 patients) or-diagnosis of MDD (DSM-IV-TR) (30 patients)-manifestation of depressive symptoms-no further psychiatric comorbidity on axis I and axis II (including abuse/addiction)-no serious cognitive deficitsPsychometric battery:Bipolar Depression Rating Scale (BDRS),Hamilton Depression Rating Scale (HAM-D),Montgomery-Asberg Depression Rating Scale (MADRS),Young Mania Rating Scale (YMRS).ResultsThe analysis of the BDRS scores, according to the Kolmogorov-Smimov method shows a normal distribution; the α Cronbach's coefficient shows that the the scale, in its Italian version, has considerable validity and reliability (r = 0.82). The factor analysis was verified using the Varimax rotational method: after several tests, we found 2 subscales, one linked to mixed/depressive symptoms and a second related to (hypo)manic symptoms.ConclusionsThe BDRS is a valid scale for the measurement of depression in patients with Bipolar Disorder, with a notable internal consistency (Cronbach α 0.82), a significant consistency between items/total (Cronbach α from 0.80 to 0.82) and positive correlation with other scales (MADRS r 0.67, p < 0.001; HAM-D r 0.81, p < 0.001; YMRS r 0.46 p < 0.0001), including the Young Mania Rating Scale (better than the original validation sample Berk et al., 2007).
1247 – The Role Of Modern Antipsychotics In Correction Of Neurocognitive Deficit In Schizophrenia Patients
Authors: Sofronov A. , Spikina A. , Savelyev A. 
Published: July 2013

Schizophrenia is a chronic psychotic disease which occurs as a rule in young patients and often leads to their disability. A long time it was thought that a neurocognitive deficit in schizophrenia patients is unremediable but introduction of atypical antipsychotics in the therapy of schizophrenia shows us a principal possibility of its correction. It also shows that neurocognitive deficit is a plastic heteronomous phenomenon in the structure of psychopathology.The aim of our study was to show the influence of the atypical antipsychotics and drugs which have influence on sigma receptors on the neurocognitive deficit in schizophrenia patients.Material and methodsFor our investigation we observed 167 patients with paranoid schizophrenia according to the criteria of ICD 10. Patients were randomized into 3 groups. Patients of 1st group (n = 52) received sertindole monotherapy 16–20 mg per day, patients of 2nd group (n = 67) received paliperidone 9–12 mg per day and fluvoxamine in combination with zuclopenthixole depot 150–200 mg per day.ResultsSocial functioning in patients with schizophrenia significantly improved in all three groups especially in group №3. We suppose that it was connected with activating activity of fluvoxamine.ConclusionThus the results of the study indicate the significance of differences of dynamics of neurocognitive deficit in schizophrenia and the importance of choice of biological therapy for correction of neurocognitive deficit in patients with schizophrenia.The use of modern atypical antipsychotics and drugs which can influence on sigma-receptors can restore the social functioning in young patients with schizophrenia.
1250 – Personal And Emotional Features Of Adolescents With Internet-addictive Behavior
Authors: Malygin V. , Iskandirova A. , Khomeriki N. , Smirnova E. , Antonenko A. , Merkurieva Y. , Malygin Y. 
Published: July 2013

The aim of this study was to investigate personal and emotional features of the adolescents with the Internet-addictive behavior.MaterialThe sample comprised 542 adolescents with 218 females (40,2%) and 324 males (59,8%). The mean age was 15,5 years. The main experimental group (46 adolescents) included only those respondents who had high levels of Internet addiction combined with the objective data from the questionnaire. The control group consisted of adolescents with no signs of Internet-dependent behavior of comparable age and sex (213 adolescents).ResultsThe group of adolescents with Internet-addictive behavior revealed the predominance cyclothymic, labile, asthenoneurotic, sensory, anxiety-pedantic, introverted, excitable, demonstrative and unstable types. We suggest that when characterological traits reach a level of accentuation, that becomes the factor associated with the formation of Internetaddictive behavior. The adolescents with problems of using the Internet show the general emotional instability, the tendency to experience the polar emotions simultaneously; they are excitable and have the aggressive style of communication. One of the main features of their characters is sensitivity to the danger, anxiety that caused the need to escape from the “harsh” reality. It could also be proposed that the adolescents with Internet addictive behavior separate emotions and cognitions, physicality and mentality. They isolate their own feelings and attach greater importance to the intellect. That cause the feeling of themselves as the subjects, more to do with information than with emotions, which could be poorly understood and classified.
1258 – Quality Of Life Of War Veterans With Posttraumatic Stress Disorder In Bosnia-herzegovina
Authors: Hasanović M. , Sinanović O. , Izet P. , Esmina A. , Frančišković T. 
Published: July 2013

AimTo analyze the quality of life (QoL) of war veterans in Bosnia and Herzegovina (BH) with posttraumatic stress disorder (PTSD), to analyze the interrelationship of certain segments of the quality of life and intensity of symptoms of PTSD and to analyze the interrelation of individual segments of the quality of life and overall functionality of the war veterans with PTSD.MethodThe paper analyzed the 60 war veterans who were treated at the Department for Psychiatry Tuzla, in the period March-August, 2007, and who were diagnosed with PTSD. The control group comprised of the 60 war veterans employed as active military personnel in the Army of BH, who were not on the screening test showed that they have PTSD and who were not psychiatric treated. QoL was assessed with standardized scale The Manchester brief assessment of the QoL, and the level of severity of PTSD symptoms and the presence of PTSD at the time of the interview was assessed with Harvard trauma questionnaire, combined versions for Bosnia and Herzegovina and for Croatia.ResultsThe results of this survey indicate that the war veterans with PTSD had significantly worse QoL across all domains, as measured in almost total in relation to veterans who do not have PTSD. All individual symptoms and clusters of PTSD symptoms were negatively correlated with self-assessment of all segments of the QoL of war veterans.ConclusionsThe war veterans in post-war BH with PTSD had significantly worse QoL across all domains, related to veterans without PTSD.
1276 – Anxiety And Depression In Patients With Chronic Hepatitis c Receiving Interferon-alpha Therapy
Authors: Papari A.C. , Cozaru G.C. , Papari A. 
Published: July 2013

The existing studies point to a prevalence of clinical significant symptoms of depression and anxiety in chronic hepatitis C (CHC) patients are only scarcely investigated.The present study aims to determine the frequency with which depression and anxiety occur in patients with CHC after receiving interferon-alpha therapy. The clinical and social implications are severe and the concurrent psychiatric disorders may lead to increased morbidity and impaired quality of life.We searched for some socio-demographic and medical variables and we followed the relationship between depression and age, disease duration and duration of treatment.Were studied two groups of patients: a group of 40 patients diagnosed with CHC during interferon-alpha therapy for up to 6 months and a control group of 40 patients, newly diagnosed with CHC. We applied the Beck Depression Inventory to assess depression, and State Trait Anxiety Inventory to assess anxiety.In contrast to the untreated reference group, we found significantly increased scores for depression (p < .001) and anxiety (p < .001) during interferon-alpha therapy in the treatment group. In both groups we found higher levels of anxiety than average, suggesting that this is a greater extent associated with CHC.The treatment of co-morbid depression should follow the usual clinical guidelines and in case of major depression, or when clinically significant anxiety is present, a pharmacological approach should be made.Based on these results, we conclude that screening for depression and anxiety should be carried out routinely as part of quality of care improvement in CHC individuals.
1282 – Sleep Disturbances And Parkinson's Disease In a Hospital Setting In Romania
Authors: Dumitru M.M. , Andrei R. , Botezatu C. , Popescu C.D. , Chirita V. , Chirita R. 
Published: July 2013

IntroductionSleep disturbance is common among patients with Parkinson's disease and occurs in approximately two thirds of patients.ObjectivesThe main objective of this study was to examine the prevalence of sleep disturbances in patients with Parkinson's disease in Romania.AimsTo asses risk factors associated with excessive daytime sleepiness and nocturnal sleep disorders.Methods44 consecutive inpatients with Parkinson's disease (41% females) were included in a study of non-motor symptoms, including sleep disturbances. All participants responded to the Parkinson's Disease Sleep Scale (PDSS), where an overall score below 82 or a score below 5 on a sub-item indicate sleep disturbances. Factors associated with sleep were also investigated, with special emphasis on severity of Parkinson's disease, fatigue, mental health and restless legs syndrome (RLS).ResultsThe mean age was 67.8 years (range 35-74); the mean Hoehn and Yahr stage was 2.4 (SD 0.8), and the mean UPDRS part III was 22.6 (SD 11.5). Sleep disturbances were common among patients with Parkinson's disease. While only 17% of the sample had an overall score below 82 on the PDSS, 70% of the patients had a score below 5 on one item. There was no significant association between Parkinson's disease severity and any of the sleep items in the PDSS.ConclusionsThe current findings call for increased awareness of sleep problems in patients with Parkinson's disease, especially focusing on the association with mental health problems, fatigue and RLS.
1287 – Nutritional Status As Measured By Bmi And Mci-to-dementia Progression In 24 Months Observation
Authors: Magierski R. , Fendler W. , Sobow T. 
Published: July 2013

IntroductionLower baseline BMI has been associated with more rapid cognitive decline in MCI [Cronk B et al., 2010] while data considering risk of progression to an overt dementia is lacking.ObjectiveTo examine the potential relationship between baseline BMI and changes in BMI over time and the risk of MCI-todementia progression.MethodsFifty four subjects with MCI were observed longitudinally over the period of 24 months. BMI was measured at baseline and yearly. Demographic and clinical (including the presence of concomitant somatic diseases and neuropsychiatric symptoms) data was collected at baseline. After conducting univariate comparisons, factors which p was < 0,15 were entered into multivariate models.ResultsSubjects with MCI who progressed to dementia had lower BMI at baseline (mean values 19,6 vs 22,5; p< 0,001) and were losing more weight over time (mean values of BMI change over 2 years -1,3 vs -6,5; p< 0,001). In multivariate analysis higher baseline BMI remained as a protective factor (OR= 0,6; 95% CI 0,4-0,9) while losing weight over time (OR= 1,3; 95% CI 1,1-1,5) and apathy could be considered as risk factors. Interestingly the presence of apathy was correlated to lower BMI values both at baseline and over time.ConclusionBoth lower baseline BMI and a tendency for continuing weight lost over time may be factors related to risk of MCI-to-dementia progression. Correlation of nutritional status measured by BMI with apathy merits further exploration.
1289 – The Burnout Syndrome Occurrence Among The Students Of The Medical University Of Silesia In Katowice, Poland
Authors: Urbański M. , Kukanova A. , Wincierz A. , Krysta K. , Krupka-Matuszczyk I. 
Published: July 2013

IntroductionThe essence of the burnout syndrome is defined as an simultaneous occurrence all of the following symptoms: emotional use-up, devalued view on own achievements and the depersonalization. It is most commonly observed in professions that require frequent contact to other people. Exhausting work above self-capabilities, the disability to deal with problems concerning the work environment combined with chronic stress they are considered to cause psychical and physical disorders, manifesting variously, e.g.: headaches, gastric upsets or persistent tiredness. Low self-esteem makes the human find himself incompetent and losing the point on the results of the regular tasks daily performed at a workplace.ObjectivesThe objective of the study was to analyze the desribed above problem among medical students.MethodsThe group of 509 students during 2nd, 3rd, 5th and 6th year of study inc. 371 women and 138 men was examined. The poll had been compiled within 22 different questions concerning: establishing new relationships difficulties, tiredness persistence, perceiving and dealing with own problems capability, selfestimation strength or the psychosomatic symptoms presence.ResultsThe respondents declared as follows - 50%+:persistent exhaustion right after the morning awakening, 29%: worsened relationship to closest group of family and friends, 21%: void of understanding by the nearest neighborhood, 79%: fear about first steps at the first workplace, 49%: inadequate competences to perform standalone profession tasks.ConclusionsAlthough rather a small part of the students fit all three BS symptoms defined above, at some people two of them reach.
1293 – Informing About Pre-clinical Alzheimer's Disease In The Biomarker Era: Knowledge About The Disease As a Mediating Factor
Authors: Sobow T. 
Published: July 2013

IntroductionBiomarker studies showed that the diagnosis of Alzheimer's disease (AD) can be done already years before any clinical symptoms appear. Considering the lack of effective treatments, this scientific development becomes problematic in clinical practice.ObjectiveTo examine whether the level of knowledge about AD mediates potential wish for diagnosis to be revealed in a pre-clinical phase.MethodThe Alzheimer's Disease Knowledge Scale (ADKS; Carpenter et al., 2009) has been completed by 68 healthy (with no cognitive impairment) elderly (age 62-75), 49 caregivers (close relatives) of AD patients (age 42-74) and 96 medical students sample. After ADKS completion all participants were presented a leaflet showing possible tests they could underwent (PET-based amyloid imaging, CSF-based amyloid and tau measurements and genetic tests) to establish a possible AD diagnosis in its pre-clinical phase. Attitudes about possible AD disclosure were measured using semi-structured questionnaire.ResultsA wish to AD diagnosis disclosure, independently of the clinical scenario presented (presence of symptoms, close family member suffering from AD) and the group investigated, was higher among those who scored low on ADKS scale. AD relatives, although interested in possible prevention strategies, were highly hesitant about revealing they might have AD themselves.ConclusionThe level of knowledge about AD may be associated with the decision to undergo diagnostic procedures to establish a pre-clinical diagnosis of AD. Lack of effective intervention probably determines potential patients attitudes.
1312 – Interparental Conflict And Adolescent Suicidality
Authors: Jelenova D. , Lacinova L. , Prasko J. 
Published: July 2013

IntroductionHigh rate of suicidal behavior during adolescence draws the research attention. Numerous motives of suicide attempts were previously described; nevertheless most adolescents reported disturbed relationships with peers and parents. Family background seems to be important, especially the relationship between parents.ObjectiveTo examine suicidality in adolescents and recognize the risk factors, especially adolescents’perceptions of interparental conflict.AimTo explore risk factors associated with suicidality in adolescents, with regard to relationships within family, with friends and personality characteristics.MethodsThe sample consisted of 161 Czech students (14-16 years old) who anonymously completed four questionnaires: CPIC (Children’s Perception of Interparental Conflict Scale), IPPA (The Inventory of Parent and Peer Attachment), PAQ (Personality Assessment Questionnaire), CASPI (Child-Adolescent Suicidal Potential Index).ResultsVery high level of psychosocial distress was found in 45 % of respondents, 25 % admitted suicidal ideation or a history of suicidal attempt. The perceived interparental conflict, not the divorce, was confirmed as the important aspect for higher suicidal risk in adolescents. The perceived threat (higher feelings of danger resulting from the conflict situation and inability to influence the conflict) is the main feature of interparental conflict responsible for child maladjustment. Statistically significant differences between suicidal and non-suicidal adolescents were also found in the level of felt security in relationship with their mother, father and with peers. These groups differed in some personal characteristics too (aggressivity level, negative self-perception, emotional instability, and pessimism).ConclusionResults highlight potential targets for intervention among adolescents. Further research is needed to find sensitive predictors.
1327 – TYM (test Your Memory) a New, Sensitive Screening Instrument For Dementia -evaluating In Poland
Authors: Szczesniak D. , Wojtynska R. , Trypka E. , Rymaszewska J. 
Published: July 2013

IntroductionThe aging of the world population implies challenges in the area of diagnosis in geriatric psychiatry.ObjectivesThe Test Your Memory (TYM) is a short cognitive instrument designed for the detection of Alzheimer’s disease (AD). Its diagnostic utility for application in Polish clinical practice was evaluated in the study.AimsThe Polish version of TYM as a screening instrument in AD and MCI patients versus healthy control subjects were evaluated.MethodsIn this study 66 patients with probable AD (mean age 74,4 ± 9,1), 71 patients with MCI (mean age 66,3 ± 10) and 94 healthy controls (mean age 71,6 ± 8,3) were assessed. The Polish version of TYM was used after receiving permission from the author and conducting translation and validation process.ResultsThe average total TYM score were 45.4 in healthy controls, 41.1 in MCI patients and 23.4 in AD patients. The statistical analysis illustrated that TYM differentiate the AD patients from MCI patients, as well as from healthy control group. Nevertheless, it was found that the tool was not useful in conducting the differential diagnosis between MCI patients and healthy controls. Post hoc testing showed significant impairment in performance for participants aged ≥ 75 and educated in primary level between those educated in secondary and higher level.ConclusionsThe Polish version of the TYM is a useful instrument and is seen as a superior screening test in clinical practice. However the age and the level of education of respondents should be considered as important factors affecting the interpretation of the final score.
1328 – Postradiation Intelligence Impairment
Authors: Loganovsky K.N. , Zdorenko L.L. 
Published: July 2013

BackgroundCognitive impairment in the remote period of Acute Radiation Sickness (ARS) is an expected outcome.AimThis study was undertaking to examine the contribution of irradiation on the intelligence deterioration.MethodsIn 14-15 years after the Chernobyl accident a cross-sectional IQ-study on ARS-patients (n = 29) and normal controls (n = 24) was done. Verbal (VIQ), Performance (PIQ) and Full (FIQ) IQs were assessed by adapted version of the Wechsler Adult Intelligence Scale (WAIS). Pre-exposure IQ was estimated with the regression equation by Dr. Beilin Gao (China).ResultsVIQ and FIQ is lower in ARS-patients. Dose of 1 Gy could be realized in FIQ deterioration on 4.1-6 scores at 1-3.8 Gy. FIQ reducing on 1 score could be resulted by 0.17-0.24 Gy. According to pre-exposure IQ estimations, IQ deterioration in ARS-patients is in 2-3 times much more than in control. In ARS-patients this IQ deterioration is significant (more than SD). Non-radiation confounding factors are analyzed.ConclusionsRefusal of alternative explanations of the cognitive deficit among ARS-patients could testify to radiation nature of this effect. Reducing of VIQ and FIQ are the evidence of brain organic syndrome with paramount involvement of the left, dominating, hemisphere in the remote period of ARS.