bluuebunny/crossref_metadata_2025_split huggingface dataset:
Anterior Resection for Rectal Cancer and Visceral Blood Flow: An Explorative Study
Authors: Rutegård M. , Hassmén N. , Hemmingsson O. , Haapamäki M. M. , Matthiessen P. , Rutegård J. 
Published: August 2015

Background and Aims: Impaired blood perfusion may be implicated in anastomotic leakage after anterior resection for rectal cancer. We investigated whether high ligation of the inferior mesenteric artery or total mesorectal excision compromises visceral blood flow in the colonic limb and the rectal stump, respectively. Material and Methods: A prospective cohort study was conducted in a university hospital setting. We used Laser Doppler flowmetry to evaluate the impact of level of tie on colonic limb perfusion and the extent of the mesorectal excision on the rectal blood flow. In the rectum, different quadrants were also assessed. The Mann–Whitney U test was used to compare mean blood flow ratios between groups. Results: Some 23 patients were recruited in a convenience sample during a period in 2012–2013. The mean blood flow ratio was not decreased after high tie compared to low tie surgery (1.71 vs 1.19; p = 0.28). Total mesorectal excision reduced the mean blood flow ratio in the rectum, as compared with partial mesorectal excision (0.76 vs 1.28; p = 0.14). This was especially pronounced in the posterior aspect of the rectum (0.66 vs 1.68; p = 0.02). Conclusion: High tie ligation did not seem to decrease colonic limb perfusion, while total mesorectal excision may decrease rectal blood flow. The posterior quadrant of the rectum might be particularly vulnerable to the dissection involved in total mesorectal excision.
Factors Influencing Quality of Life among People Living with HIV in Coastal South India
Authors: Arjun Banagi Yathiraj , Unnikrishnan Bhaskaran , Ramapuram John T. , Thapar Rekha , Mithra Prasanna , Kumar Nithin , Madi Deepak , Kulkarni Vaman , Holla Ramesh , Darshan Bhagawan 
Published: August 2015

Background: Antiretroviral therapy (ART) has increased life expectancy of HIV/AIDS patients, but the quality of life (QOL) still remains the same. Methods: In this cross-sectional study, 356 people living with HIV (PLHIV) were interviewed to assess their QOL using WHOQOL-HIV BREF questionnaire. The association between QOL with sociodemographic, clinical and cohabitation status of the participants was tested using ANOVA and Student t-test, and p value < .05 was considered statistically significant. Results: Physical domain of QOL showed maximum score of 16.4, while a minimum score of 12.2 was seen in social relationship domain. Participants with higher socioeconomic status (SES) and self-motivated to take ART had shown better scores across all the domains of QOL ( p < .05). Conclusion: In our study, quality of life was high among males, younger patients, married participants, higher socioeconomic status, longer duration of ART, self-motivation to take ART, absence of opportunistic infection, and with higher CD4 count.
Stem cell therapy: a novel treatment option for cerebral malaria?
Authors: Wang Wei , Qian Hui , Cao Jun 
Published: August 2015

AbstractCerebral malaria, a severe form of the disease, is one of the most severe complications of infection with Plasmodium parasites and a leading cause of malaria mortality. Currently available antimalarial therapy has proven insufficient to prevent neurological complications and death in all cases of cerebral malaria. Souza and colleagues observed that transplantation of bone marrow-derived mesenchymal stromal cells (BM-MSCs) increased survival, reduced parasitemia, decreased malaria pigment accumulation in the spleen, liver and kidney, elevated Kupffer cell count in liver, alleviated renal injury and lung inflammation, and improved lung mechanics in an experimental mouse model of cerebral malaria. Although plenty of challenges lie ahead, their findings show the promise of BM-MSC therapy for the treatment of cerebral malaria.
Time evolution of face recognition in accessible scenarios
Authors: Blanco-Gonzalo Ramon , Poh Norman , Wong Rita , Sanchez-Reillo Raul 
Published: August 2015

AbstractUp to now, biometric recognition
has shown significant advantages as to be considered a reliable solution for security systems in mobile environments. Nevertheless, due to the short lifetime of biometrics in mobile devices, a handful of concerns regarding usability and accessibility need to be covered in order to meet users’ requirements. This work is focused on analysing the usability and accessibility of a face recognition system used by visually impaired people, focusing on the time spent in the process, which is a critical aspect. Specifically, we cover different key questions including which kind of feedback is more useful for visually impaired users and beneficial for performance and how is the performance evolution in contrast with the time spent in the recognition. Our findings suggest that several parameters improve along with the time spent in the process, including performance. The audio feedback provided in real time involves also better performance and user experience than instructions given previously.
Relationship between family meal frequency and individual dietary intake among diabetic patients
Authors: Ruhee Divya , Mahomoodally Fawzi 
Published: August 2015

Abstract
Background
Notoriously, the island of Mauritius has one of the highest prevalence of diabetes in the world. Management of the disease is very important and family meals are undoubtedly beneficial to patients as they promote the development of healthy eating behaviours and food choices. This study has aimed to probe into potential relationship(s) between family meal frequency and individual dietary intake among diabetic patients and to establish whether family cohesion may be a plausible mediator of this relationship.

Methods
A cross-sectional survey was carried out with a random sample of 384 diabetic patients. The Family Adaptability and Cohesion Evaluation Scale III was used to obtain information on two general aspects of family functioning, that is, cohesiveness and adaptability. Chi-squared (χ2) tests, independent sample t-tests and one-way ANOVA were used to determine statistical significance. Pearson correlation was used to examine associations between family meal frequency, individual dietary intake and family cohesion. Hierarchical linear regression models were performed for the mediation analysis.

Results
Family meal frequency (breakfast, lunch and dinner) was observed to be positively associated with intake of fish, raw vegetables, dried and fresh fruits, low-fat milk, cheese, yogurt, nuts and light butter and negatively associated with intake of red meat, white rice, white bread, whole egg fried, chocolates, fried cakes, burgers, chips, and fried noodles/rice. Average mediation (52.6 %) was indicated by family cohesion for the association between family meal frequency and individual dietary intake among diabetic patients. Sobel’s test further confirmed the trend towards complete mediation (z = 15.4; P < 0.05).

Conclusions
A strong relationship between family meal frequency and individual dietary intake among diabetic patients was recorded. The present study is one of the few studies that have examined family cohesion as a mediator of the relationship and to our best knowledge is the first work to demonstrate a trend towards complete mediation. Results obtained can be used by health professionals to devise strategies for increasing knowledge and awareness of both diabetic patients and their respective families to curd down this public health burden.
Carcinogenic effects of circadian disruption: an epigenetic viewpoint
Authors: Salavaty Adrian 
Published: August 2015

AbstractCircadian rhythms refer to the endogenous rhythms that are generated to synchronize physiology and behavior with 24-h environmental cues. These rhythms are regulated by both external cues and molecular clock mechanisms in almost all cells. Disruption of circadian rhythms, which is called circadian disruption, affects many biological processes within the body and results in different long-term diseases, including cancer. Circadian regulatory pathways result in rhythmic epigenetic modifications and the formation of circadian epigenomes. Aberrant epigenetic modifications, such as hypermethylation, due to circadian disruption may be involved in the transformation of normal cells into cancer cells. Several studies have indicated an epigenetic basis for the carcinogenic effects of circadian disruption. In this review, I first discuss some of the circadian genes and regulatory proteins. Then, I summarize the current evidence related to the epigenetic modifications that result in circadian disruption. In addition, I explain the carcinogenic effects of circadian disruption and highlight its potential role in different human cancers using an epigenetic viewpoint. Finally, the importance of chronotherapy in cancer treatment is highlighted.
Elevated C-reactive protein and late-onset bipolar disorder in
78 809 individuals from the general population
Authors: Wium-Andersen Marie Kim , Ørsted David Dynnes , Nordestgaard Børge Grønne 
Published: August 2015

BackgroundNo prospective studies have examined the role of C-reactive protein (CRP)
in late-onset bipolar disorder.AimsWe tested the hypothesis that elevated levels of CRP are associated
cross-sectionally and prospectively with late-onset bipolar disorder, and
that such an association possibly is causal.MethodWe performed cross-sectional and prospective analyses with a median
follow-up time of 5.9 years (interquartile range: 4.4– 7.6) in 78 809
individuals from the general population, and used genetic variants
influencing CRP levels to perform a Mendelian randomisation study.ResultsElevated levels of CRP were associated both cross-sectionally and
prospectively with late-onset bipolar disorder. When CRP was on a
continuous scale, a doubling in CRP yielded an observational odds ratio
for late-onset bipolar disorder of 1.28 (1.08–1.52) with a corresponding
causal odds ratio of 4.66 (0.89–24.3).ConclusionElevated CRP is associated with increased risk of late-onset bipolar
disorder in the general population which was supported by the genetic
analysis.
Surgery-Induced Weight Loss Is Associated With the Downregulation of Genes Targeted by MicroRNAs in Adipose Tissue
Authors: Ortega Francisco J. , Mercader Josep M. , Moreno-Navarrete José M. , Nonell Lara , Puigdecanet Eulàlia , Rodriquez-Hermosa José I. , Rovira Oscar , Xifra Gemma , Guerra Ester , Moreno María , Mayas Dolores , Moreno-Castellanos Natalia , Fernández-Formoso José A. , Ricart Wifredo , Tinahones Francisco J. , Torrents David , Malagón María M. , Fernández-Real José M. 
Published: August 2015

Context:
Molecular mechanisms associated with physiological variations in adipose tissue (AT) are not fully recognized. The most recent reports highlight the critical relevance of microRNAs (miRNAs) found in AT.

Objective:
To identify changes in messenger RNA (mRNA) and miRNA expressions and their interaction in human AT before and after surgery-induced weight loss.

Research Design and Setting:
Genome-wide mRNA and miRNA expressions were assessed by microarrays in abdominal subcutaneous AT of 16 morbidly obese women before and 2 years after laparoscopic Roux-en-Y gastric bypass. The association of changes in miRNAs with their respective mRNA targets was studied. The results were replicated in publicly available microarray datasets. Validation was made by real-time polymerase chain reaction in additional fat samples from 26 age-matched lean women and in isolated human adipocytes.

Results:
A total of 5018 different mRNA probe sets and 15 miRNAs were differentially expressed after surgery-induced weight loss. The clustering of similar expression patterns for gene products with related functions revealed molecular footprints that elucidate significant changes in cell cycle, development, lipid metabolism, and the inflammatory response. The participation of inflammation was demonstrated by results assessed in isolated adipocytes. Interestingly, when transcriptomes were analyzed taking into account the presence of miRNA target sites, miRNA target mRNAs were upregulated in obese AT (P value = 2 × 10−181) and inflamed adipocytes (P value = 4 × 10−61), according to the number of target sites harbored by each transcript.

Conclusions:
Current findings suggest impaired miRNA target gene expression in obese AT in close association with inflammation, both improving after weight loss.
Freshwater distributions and water mass structure in the Amundsen Sea Polynya region, Antarctica
Authors: Randall-Goodwin E. , Meredith M. P. , Jenkins A. , Yager P. L. , Sherrell R. M. , Abrahamsen E. P. , Guerrero R. , Yuan X. , Mortlock R. A. , Gavahan K. , Alderkamp A.-C. , Ducklow H. , Robertson R. , Stammerjohn S. E. 
Published: August 2015

Abstract
We present the first densely-sampled hydrographic survey of the Amundsen Sea Polynya (ASP) region, including a detailed characterization of its freshwater distributions. Multiple components contribute to the freshwater budget, including precipitation, sea ice melt, basal ice shelf melt, and iceberg melt, from local and non-local sources. We used stable oxygen isotope ratios in seawater (δ18O) to distinguish quantitatively the contributions from sea ice and meteoric-derived sources. Meteoric fractions were high throughout the winter mixed layer (WML), with maximum values of 2–3% (±0.5%). Because the ASP region is characterized by deep WMLs, column inventories of total meteoric water were also high, ranging from 10–13 m (±2 m) adjacent to the Dotson Ice Shelf (DIS) and in the deep trough to 7–9 m (±2 m) in shallower areas. These inventories are at least twice those reported for continental shelf waters near the western Antarctic Peninsula. Sea ice melt fractions were mostly negative, indicating net (annual) sea ice formation, consistent with this area being an active polynya. Independently determined fractions of subsurface glacial meltwater (as one component of the total meteoric inventory) had maximum values of 1–2% (±0.5%), with highest and shallowest maximum values at the DIS outflow (80–90 m) and in iceberg-stirred waters (150–200 m). In addition to these upwelling sites, contributions of subsurface glacial meltwater could be traced at depth along the ∼ 27.6 isopycnal, from which it mixes into the WML through various processes. Our results suggest a quasi-continuous supply of melt-laden iron-enriched seawater to the euphotic zone of the ASP and help to explain why the ASP is Antarctica’s most biologically productive polynya per unit area.
Improve Synergy Between Health Information Exchange and Electronic Health Records
to Increase Rates of Continuously Insured Patients
Authors: Gold Rachel , Burdick Tim , Angier Heather , Wallace Lorraine , Nelson Christine , Likumahuwa-Ackman Sonja , Sumic Aleksandra , DeVoe Jennifer E. 
Published: August 2015

Introduction: The Affordable Care Act increases health insurance options, yet many
Americans may struggle to consistently maintain coverage. While health care providers
have traditionally not been involved in providing insurance enrollment support to their
patients, the ability for them to do so now exists. We propose that providers could
capitalize on the expansion of electronic health records (EHRs) and the advances in
health information exchanges (HIEs) to improve their patients’ insurance coverage rates
and continuity.Evidence for Argument: We describe a project in which we are building
strategies for linking and thus improving synergy between payer and EHR data. Through
this effort, care teams will have access to new automated tools and increased EHR
functionality designed to help them assist their patients in obtaining and maintaining
health insurance coverage.Suggestion for the Future: The convergence of increasing EHR
adoption, improving HIE functionality, and expansions in insurance coverage options,
creates new opportunities for clinics to help their patients obtain public health
insurance. Harnessing this nascent ability to exchange information between payers and
providers may improve synergies between HIE and EHRs, and thus support clinic-based
efforts to keep patients continuously insured.
LASeR: Lizenz-Administrationssystem für e-Ressourcen
Authors: Rupp Daniel A. , Selbach Michaela 
Published: August 2015

Zusammenfassung:
Vor dem Hintergrund eines zunehmenden Anteils von E-Medien fehlt Bibliotheken ein Instrument, um bilaterale, konsortiale und Allianzlizenzen zu verwalten. Der Aufsatz beschreibt das von der DFG teilgeförderte Projekt „Electronic Resource Management System“, welches zum Ziel hat, das bundesweit einsetzbare, mandantenfähige ERM-System LASeR zu entwickeln. In den bisher geförderten Arbeitspaketen wurde auf der Basis von Experteninterviews, Nutzerumfrage, Anbietergesprächen und der Evaluation bestehender Systeme ein Konzept erstellt, auf dessen Basis LASeR im Fall der Weiterförderung realisiert wird.
Classification of correlation-immune and minimal correlation-immune Boolean functions of 4 and 5 variables
Authors: Alekseev Evgeniy. K. , Karelina Ekaterina K. 
Published: August 2015

AbstractA classification of correlation-immune and minimal corelation-immune Boolean function of 4 and 5 variables with respect to the Jevons group is given. Representatives of the equivalence classes of correlationimmune functions of 4 and 5 variables are decomposed into minimal correlation-immune functions. Characteristics of various decompositions of the constant function 1 into minimal correlation-immune functions are presented.
Dietary habits and sedentary behaviors among health science university students in Bahrain
Authors: Musaiger Abdulrahman O. , Awadhalla Muyssar S. , Al-Mannai Mariam , AlSawad Muneera , Asokan G.V. 
Published: August 2015

Abstract

Objective:
The aim of this study was to investigate the dietary patterns and sedentary behaviors among university students in Bahrain.

Materials and methods:
A cross-sectional study was carried out with students of the College of Health Sciences in Bahrain using a self-reported questionnaire. All the students enrolled in this college were included in this study (642 students; 90 males and 552 females). The mean age of the sample was 20.1±2.0 years. A pre-tested questionnaire was used to collect information on the students’ breakfast intake, snacking, food frequency intake, and sedentary habits.

Results:
More than 50% of the students did not consume breakfast on a daily basis. A statistically significant difference (p<0.003) was found between males (19%) and females (35%) in relation to the intake of an afternoon snack. There were no significant gender differences regarding frequency of food intake, except for carbonated beverages (p<0.001) and nuts (p<0.047) consumption. Females were more likely than males to spend time watching television, use the Internet, use a mobile phone and sleep; however, the only significant difference found was for Internet use (p<0.003). Being physically active on a daily basis was more prevalent among males (41.6%) than females (16%) (p<0.001). Females (42.9%) were more prone to sleep for less time (<7 h) than males (34.4%)(p<0.08).

Conclusion:
The findings indicated that a high percentage of health science students in Bahrain had unhealthy dietary habits and sedentary behaviors. Thus, an intervention program to promote healthy dietary patterns and lifestyle habits among university students is highly recommended.
Adipokine, adropin and endothelin-1 levels in intrauterine growth restricted neonates and their mothers
Authors: Aydin Halil Ibrahim , Eser Ayla , Kaygusuz Ikbal , Yildirim Sevgi , Celik Tugrul , Gunduz Suzan , Kalman Suleyman 
Published: August 2015

AbstractIntrauterine growth retardation/restriction (IUGR) is associated with fetal malnutrition. It has consequences for later life including increased incidence of obesity, diabetes mellitus, cardiovascular disease (CVD), and metabolic syndrome. Adipokines (adiponectin and leptin), adropin, and endothelin-1 are associated with obesity and metabolic syndrome regulation. Intrauterine changes in these mediators could affect programming of later adult obesity and metabolic syndrome. Our objectives were to compare the levels of these mediators in both cord and maternal blood between IUGR pregnancies and control, healthy pregnancies, and to study the correlation of adipokines with adropin and endothelin-1 in maternal and cord blood in IUGR pregnancies as well as in healthy control pregnancies. Maternal and cord blood samples were taken from 16 women with IUGR pregnancies and 16 women with healthy pregnancies. Serum levels of leptin, adiponectin, adropin, and endothelin-1 were measured by ELISA. Maternal blood adropin levels were significantly lower in the IUGR group than in the control group; the other mediators did not differ significantly. There was a positive correlation between maternal blood adropin and endothelin levels. (r=0.731, P=0.001) in the control but not the IUGR group. Cord blood adropin and adiponectin levels were significantly lower in the IUGR group compared with the control group, while leptin or endothelin-1 did not differ significantly. There was a negative correlation between adropin and leptin (r=–0.704, P=0.001) in the IUGR but not the control group cord blood. There were also positive correlations between endothelin and adropin for both groups (r=0.594, P=0.006; r=0.560, P=0.010, respectively); to the best of our knowledge, this is the first report of such a correlation. Differences in fetal expression of adropin and adiponectin in IUGR could influence programming of obesity, metabolic syndrome, diabetes, and CVD in later life.
Variational assimilation of observation data in the mathematical model of the Baltic Sea dynamics
Authors: Agoshkov Valeriy I. , Parmuzin Eugene I. , Zalesny Vladimir B. , Shutyaev Victor P. , Zakharova Natalia B. , Gusev Anatoly V. 
Published: August 2015

AbstractA mathematical model of the dynamics of the Baltic Sea is considered. A problem of variational assimilation of sea surface temperature (SST) data is formulated and studied. Based on variational assimilation of satellite observation data, an algorithm solving the inverse problem of heat flux restoration on the interface of two media is proposed. The results of numerical experiments reconstructing the heat flux functions in the problem of variational assimilation of SST observation data are presented. The influence of SST assimilation on other hydrodynamic parameters of the model is considered.
Monte Carlo simulation of ring-shaped returns for CCD LIDAR systems
Authors: Prigarin Sergei M. , Aleshina Tat’yana V. 
Published: August 2015

AbstractAlgorithms for stochastic simulation of spatial-temporal CCD LIDAR returns are presented in the paper. Conditions for a laser pulse to generate an expanding ring of light in a cloud layer are studied by Monte Carlo numerical experiments. The algorithms developed here are aimed to supercomputer simulation.
New distribution and elevation records for the snake Pseudelaphe flavirufa Cope, 1867 (Squamata: Colubridae) in Oaxaca, Mexico — RETRACTED
Authors: Mata-Silva Vicente , Wilson Larry David , Johnson Jerry D. , Mata-González Stephanye , Ramírez-Bautista Aurelio , García-Grajáles Jesús 
Published: August 2015

It was brought to our attention that, unfortunately, the species of our note was misidentified. It is in fact Senticolis triaspis (Cope, 1866). Therefore, the first record of Pseudelaphe flavirufa for the Municipality of San Bartolo Coyotepec and for the floristic-faunistic area number 6 (Valles Centrales) of Oaxaca is no longer valid, as well as the new elevation record.We apologize for our mistake. The authors.21 February 2014.