bluuebunny/crossref_metadata_2025_split huggingface dataset:
23-PUB: Reduction of Residual Lipid Risk in Patients with Type 2 Diabetes and Mixed Dyslipidemia Treated with a Fixed-Dose Combination of Atorvastatin/Fenofibrate
Authors: SANDER-PADILLA JOSE G. , LUGO-SÁNCHEZ LAURA A. , RIOS-BRITO KEVIN F. , RODRIGUEZ-ROCANDIO KARLA E. , ARGUEDAS MARÍA M. , FLORES-HUANOSTA DIANA , RODRIGUEZ-VAZQUEZ ILEANA C. , GONZALEZ-CANUDAS JORGE , ROMERO YULIA 
Published: July 2024

Introduction and Objective: The persistence of a high cardiovascular risk not dependent on LDL-C levels constitutes the residual cardiovascular risk of lipid origin (RLR). Lipid-lowering treatment does not always consider the modification of RLR. The present study aimed to evaluate the changes in RRL profile in patients with T2D and dyslipidemia treated with a fixed-dose combination (FDC) of Atorvastatin/Fenofibrate.
Methods: A phase IIIb, randomized, prospective, double-blind, multicenter study in the Mexican population with diagnosis of T2D and mixed dyslipidemia. Patients were randomized to the Atorvastatin/Fenofibrate 20 mg/160 mg or Atorvastatin 20 mg once daily for four months. As part of the RLR evaluation, Triglycerides/HDL-C, residual cholesterol, Total cholesterol/HDL-C, and the triglycerides-to-glucose index (TyG) were estimated. Student's t-test and McNemar test (differences within groups) χ2, and independent samples Student's t-test were applied.
Results: We included 65 patients with an average age of 56.8 ± 10.4 years. After two months of follow-up, there was a triglycerides reduction of -132.7 ± 145.3 mg/dL in the FDC group and of -68.7 ± 75.7 mg/dL with Atorvastatin therapy, while for the fourth month, the reduction was -138.3 ± 123.7 mg/dL and -60.5 ± 80.1 mg/dL, respectively. When evaluating RLR, both groups experienced a reduction in this profile, after 2 and 4 months of evaluation. However, when comparing the mean change reductions between groups of Triglycerides/HDL-C ratio (-3.9 vs -1.3, p=0.020), residual cholesterol (-19 vs -9.4, p= 0.018), and TyG (-0.7 vs -0.2, p=0.002) a superior outcome was found in FDC compared with the monotherapy group.
Conclusions: Patients receiving Atorvastatin/Fenofibrate FDC had a better reduction than monotherapy in non-LDL cholesterol-dependent RRL markers, which translates to a decrease in overall cardiovascular risk for this treatment group.

Disclosure
J.G. Sander-Padilla: Employee; Laboratorios Silanes. L.A. Lugo-Sánchez: Employee; Laboratorios Silanes S.A. de C.V. K.F. Rios-Brito: Employee; Laboratorios Silanes S.A. de C.V. K.E. Rodriguez-Rocandio: Employee; Laboratorios Silanes S.A. de C.V. M.M. Arguedas: Employee; Laboratorios Silanes S.A. de C.V. D. Flores-Huanosta: Employee; Laboratorios Silanes. I.C. Rodriguez-Vazquez: Employee; Laboratorios Silanes S.A. de C.V. J. Gonzalez-Canudas: Employee; Silanes SA CV. Y. Romero: Employee; Laboratorios Silanes.

Funding
Laboratorios Silanes
Pendidikan Agama Islam Berwawasan Multikultural
Authors: Yahdi Muhammad 
Published: July 2024

Multikulturalisme memiliki Sejarah Panjang karena bersamaan mulitikultural dengan lahirnya Indonesia, keragaman budaya, ras, agama, suku dan warna kulit. Selain itu beragam pula cara Masyarakat mencari dan melanjukan kehidupan, ada yang bekerja disektor pertanian, perikanan, jasa, dan pegawai pemerinta dan swasta. Keragaman menjadi bahagian penting dalam pengelolaan dan sistem kemasyarakatan. Hal ini dapat diihat dari negara, Pancasila dan semboyan dari Bhineka Tunggal Ika.Kemajemukan berdimensi banyak sisi ada sisi positifnya adapula negatifnya. Sisi positif dengan keragaman Masyarakat dapat tolong menolong, bantu membantu, saling menghargai, menjadi satu kesatuan dalam wilayah. Disisi lain yaitu sisi negative dengan terjadinya berbagai konflik antarkelompok maupun masyarakat, yang dapat menimbulkan instabilitas keamanan dan ketidak harmonisan sosial. Krisis terjadinya berdimensi multidimensi di dalam negeri, merupakan bagian dari problem kultural yang salah satu penyebabnya adalah kemajemukan kultur yang ada dalam masyarakat.
KEMAMPUAN KOMUNIKASI MATEMATIS SISWA KELAS VIII PADA MATERI BANGUN DATAR DITINJAU DARI GAMBAR MASJID
Authors: Zulkarnain Zulkarnain , Sarassanti Yumi 
Published: July 2024

Penelitian bertujuan untuk mengetahui kemampuan komunikasi matematis siswa kelas VIII pada materi bangun datar ditinjau dari gambar masjid. Penelitian ini dilakukan dengan menggunakan metode penelitian deskriptif, dengan pendekatan kuantitatif adalah jenis penelitian yang bertujuan untuk menggambarkan fenomena atau karakteristik suatu populasi atau sampel secara sistematis. Seluruh siswa kelas VIII B MTS Mujahidin berpartisipasi dalam penelitian ini sebagai populasi dan jumlah sampel pada penelitian ini adalah 15 siswa. Lembar tes dengan pertanyaan berbasis gambar dan lembar jawaban siswa berfungsi sebagai instrumen dalam penelitian ini. MTs Mujahidin di pontianak masih dalam taraf kategori sedang, yang di mana karenanya harus dilakukan upaya dalam mengembangkan kemampuan siswa dalam berkomunikasi matematis. berbentuk soal yang berisikan gambar dan lembar jawaban siswa. Hasil penelitian memberi tahu, tingkat kemampuan komunikasi matematis siswa dalam menganalisis gambar. 10 orang masih dalam kategori rendah, 3 orang dalam kategori sedang dan hanya 2 orang yang masuk ke taraf tinggi dalam konteks kemampuan komunikasi matematis, sehingga dapat dikatakan bahwasanya tingkat kemampuan komunikasi matematiskemampuan komunikasi matematis
Survey indicates addressing workplace environment, work-life balance, and flexibility are key to attracting and retaining veterinarians in academia
Authors: Fletcher Kendra N. , Bergman Mindy E. , Austin Jonathan W. , Marks Steven L. , Fingland Roger B. , Dallap-Schaer Barbara , Sanchez Chris , Chun Ruthanne , Davis Elizabeth G. , Kim Garam , Otero La Porte Yanai Y. , Edoga Emma I. , Levine Jonathan M. 
Published: July 2024

Abstract

OBJECTIVE
Referencing growing concerns over the recruitment and retention of faculty in academic veterinary medicine, the authors hypothesized that among surveyed veterinary residents and early-career faculty, work-life balance and workplace climate and culture are stronger motivators than financial considerations, regardless of demographic factors such as gender, race/ethnicity, and area of specialization.

SAMPLE
541 participants were included in data analysis.

METHODS
A mixed methods approach was utilized, incorporating both quantitative data and qualitative, free-text responses to better understand veterinary career choices by contextualizing factors associated with academic medicine.

RESULTS
Factors underpinning career-related decision-making were ranked by level of importance as (1) workplace environment/culture, (2) personal well-being/work-life balance, (3) salary and bonuses, (4) geographic location, (5) facilities and resources, (6) benefits, and (7) schedule flexibility. Desires for workload balance, schedule flexibility, support from leadership, and mentorship and collaboration were among the top themes of qualitative responses for both residents and early career faculty respondents. Factors influencing career decision-making for resident and early-career faculty are varied. Workplace environment, work-life balance, and schedule flexibility are areas that academic institutions can address and continue to improve and that are likely to positively impact entry into academia and the desire to stay.

CLINICAL RELEVANCE
This study sought to understand factors related to career decision-making and interest in academic veterinary medicine among residents and early-career faculty. Understanding these factors can support efforts to recruit and retain faculty in academic veterinary medicine.
The anti-vibrio potential of medicinal plants and their roles in enhancing resistance against vibrio infections in fish –a mini review
Authors: Shohreh Poulin , Ahmadifar Ehsan , Chandran Deepak , Yousefi Morteza , Yilmaz Sevdan , Yilmaz Ebru , Sheikhzadeh Najmeh , Harikrishnan Ramasamy , Abdel-Latif Hany M.R. 
Published: July 2024

Abstract
Vibriosis is a commonly known bacterial disease that harms a range of finfish species, causing significant mortality and high economic loss. Chemotherapeutics, antibiotics, and synthetic chemicals are broadly evaluated as effective treatment approaches; however, global concerns have arisen with the aim of decreasing or limiting the use of these compounds for the prevention and/or control of bacterial diseases in aquaculture systems. Consequently, extensive research studies have been accomplished to assess natural products such as plant parts (s), extracts, essential oils (EOSs), phytochemicals, or aromatic compounds as potential substitutes for antibiotics. These additives are rich in phytochemicals (carotenoids, alkaloids, saponins, terpenoids, flavonoids, and phenolic acids), vitamins, minerals, and others, which make them excellent feed supplements. This paper focuses chiefly on reviewing medicinal plants (herbal extracts and EOS) that possess anti-Vibrio potential (in vitro efficacy) and evaluating their ability to increase the immunity and resistance of fish against experimental challenges with Vibrio species (in vivo experiments). Furthermore, the role of herbal additives as adjuvants to enhance the efficacy of fish vaccines against vibriosis was also summarized. In brief, this review illustrates an ample number of medicinal herbs with effective effects on fish vibriosis. Identifying safe alternatives to ensure antibiotic-free and disease-free environments could be an initial step toward enhancing the sustainability of aquaculture and farming activities.
Understanding Antimicrobial Prescription Practices: Insights from Small Animal Veterinarians in North Macedonia
Authors: Shikoska Ivana , Cvetkovikj Aleksandar , Nikolovski Martin , Cvetkovikj Iskra 
Published: July 2024

Abstract
Antimicrobial resistance (AMR) is an increasing global concern in small animal veterinary practices. The overuse and misuse of antimicrobials in companion animals can contribute to the spread of AMR between animals and humans. This study aimed to assess small animal veterinarians’ knowledge, attitudes, and behaviors towards antimicrobial use (AMU) and AMR in North Macedonia. A web-based questionnaire was developed, including questions addressing demographics, owner influence on antibiotic prescription and prescribing practices. The response rate of the small animal veterinarians was 47.50% (57/120), with most of them (84.20%) having 1-15 years of work experience. Pearson’s chi-square test of independence was used for contingency tables that met the chi-square assumption, and Fisher’s exact test was conducted for contingency tables that did not. Most veterinarians responded that they had perceived pressure and direct demands from pet owners to prescribe antimicrobials (35.09% frequently, 45.61% occasionally). In the survey, 50.77% of the veterinarians reported frequently administering antibiotics without conducting bacteriological or antimicrobial susceptibility testing. They typically resorted to these tests in cases with recurrent infections, such as skin infections (19.63%), or when empirical therapy is ineffective (14.72%). Based on the findings, it can be concluded that veterinarians play a crucial role in tackling the AMR in North Macedonia. The lack of stewardship programs or guidelines for responsible antimicrobial use in companion animals is a critical issue that requires urgent attention, emphasizing the vital role of veterinarians in combating AMR.
Pneumatocele em criança
Authors: Cotrim Paolla Machado , Emidio Izaura Costa Rodrigues 
Published: July 2024

Objetivo: Discutir sobre as características clínicas e o manejo terapêutico adotado a respeito da pneumatocele, relatando o caso de um paciente portador da doença e comparando os dados do caso com os da literatura. Detalhamento do caso: Paciente com 2 anos de idade, sexo masculino. Foi admitido na UPA pediátrica com histórico de tosse seca associado à febre (não aferida) por 3 semanas, evoluindo com desconforto respiratório leve. Fez uso de Amoxicilina + Clavulanato devido quadro de amigdalite. Porém, após 4 dias de tratamento, evoluiu com febre. Paciente foi encaminhado para a sala amarela e iniciado Ceftriaxone 100 mg/kg/dia, Oxacilina 200 mg/kg/dia e hidratação venosa de manutenção. Devido a piora evolutiva e complicação do quadro, realizou-se toracocentece e toracostomia, com drenagem pleural e colocação de dreno em selo d’água à direita. Drenou líquido purulento e ar. Foi optado pela troca do esquema de antibióticos. Considerações finais: Conclui-se que o tratamento da pneumatocele não é específico. Em geral, realiza-se tratamento conservador, porém quando há exacerbação do quadro, com piora do desconforto respiratório e expansão da pneumatocele, considera-se o procedimento cirúrgico. Em pacientes com pneumatoceles de causa infecciosa, a antibioticoterapia quase sempre é empírica devido à dificuldade de isolamento do agente.
Space tourism and its impact on humanity
Authors: Мусякаева К.И. 
Published: July 2024

Проанализированы многочисленные публикации на тему космического туризма. В данной статье объектом исследования является туризм в космосе, выясняются и прогнозируются видение Земли из космоса, невесомость, опыт работы на высоких скоростях. Автором приводятся данные, позволяющие сделать вывод о космическом туризме в ближайшие 5 лет. Предлагается создание школы для космических гидов и инженеров нового поколения, так как данные направления будут востребованы в ближайшие 3–5 лет.
Numerous publications on the topic of space tourism have been analyzed. In this article, the object of research is tourism in space, the vision of the Earth from space, weightlessness, experience at high speeds are clarified and predicted. The author provides data allowing to draw a conclusion about space tourism in the next 5 years. It is proposed to create a school for space guides and engineers of a new generation, since these areas will be in demand in the next 3–5 years.
WHAT DID MEDIEVAL NOVGORODANS WRITE WITH ON THE WALLS?
Authors: Медынцева А.А. 
Published: July 2024

В заметке идет речь о новооткрытых надписях-граффити в Софийском соборе Новгорода, написанных по сырой глине якобы «ногтями». Но лексические и археологические данные позволяют утверждать, что имеется в виду - писание когтем, клыком животного или обычным писалом.
he paper deals with newly discovered graffiti inscriptions in the Cathedral of St. Sophia in Novgorod written on wet clay plaster, allegedly, with ‘nails’. However, lexical and archaeological data suggest that in this case writing with a nail means writing with an animal tooth or a common stylus.
IMPORTED CERAMICS FROM THE EXCAVATIONS IN THE GRAND KREMLIN PUBLIC GARDEN IN 2019-2021
Authors: Коваль В.Ю. 
Published: July 2024

В ходе раскопок, проводившихся Институтом археологии РАН в 20192021 гг. на территории Большого сквера Московского Кремля, собрана самая крупная за все годы археологических исследований в Кремле коллекция импортной керамики. Среди них к домонгольскому времени относились только обломки византийских амфор (из Трапезунда и Халкиды). Основную массу керамики XIII-XV вв. составляли полуфаянсы (преимущественно чаши), изготовленные в столичных городах Золотой Орды, размещавшихся на Нижней Волге. Эта керамика представлена несколькими группами, различавшимися по декору и цвету глазури. Из Золотой Орды доставлялась также неполивная керамика с тисненым декором. Небольшие серии составляли полуфаянсы Турции и Ирана XVI-XVII вв., а также селадоны и фарфор из Китая XIV-XVII вв. Импорты из Западной Европы (Германии) были единичны.
During the excavations conducted by the Institute of Archaeology, RAS, in the Grand Kremlin Public Garden in 2019-2021 an assemblage of imported ceramics was collected. It is now the largest collection in all the years of archaeological research in the Moscow Kremlin. The ware of the pre-Mongol invasion period included only fragments of Byzantine amphorae (from Trabzon and Chalcis). Semifaience (predominantly, cups) made in the capital cities of the Golden Horde in the Lower Volga accounted for a greater share of ceramics from the 13th-15th centuries. The ceramics are represented by several groups differentiated by decoration and color of the glaze. Non-glazed ware with impressed decoration was also brought from the Golden Horde. Small series included semifaience from Turkey and Iran of the 16th-17th centuries as well as celadons and porcelain from China of the 14th-17th centuries. Imports from Western Europe (Germany) were very rare.
SOME METHODS OF STUDYING STONE MATERIAL FROM ARCHAEOLOGICAL SITES
Authors: Хотылев А.О. , Ольховский С.В. , Хотылев О.В. , Майоров А.А. , Щепелев Ф.С. 
Published: July 2024

В статье изложен комплексный подход к идентификации регионов происхождения каменного материала, найденного в античных постройках Фанагории (рис. 1; 2). Сочетание методов описания формы (рис. 2) и ряда анализов состава (рис. 3) в случае некоторых горных пород позволяет определить не только условия их образования и обстановку, из которой они были отобраны для строительства, но и регион их происхождения. Применение указанного подхода позволило нам убедительно локализовать районы происхождения некоторых категорий каменного материала на побережьях Средиземного, Эгейского и Черного морей (рис. 1).
The paper describes an approach to identifying the regions where stone material found in Phanagoria constructions originated. The combination of methods used to describe the form and a number of analyses of the elemental composition of some rock types help researchers not only to determine formation conditions and conditions in which they were selected for construction but also identify the origin of the rocks. The application of this approach enabled us to identify the areas in the Mediterranean, Aegean and Black seas coastlines where some rock types originated.
HOUSING DEVELOPMENT IN THE BISHOP’S COURT ACCORDING TO THE DENDROCHRONOLOGICAL STUDY DATA
Authors: Тарабардина О.А. 
Published: July 2024

В статье систематизированы материалы дендрохронологического исследования древесины из раскопок разных лет на территории новгородского Владычного двора. В ходе исследований удалось установить дендродаты 82 образцов застройки и определить время строительства 19 сооружений XII-XIX вв. Анализ количественного и хронологического распределения дендродат позволил обосновать датировку сооружений и выявить периоды активного строительства в этой части Детинца. В слоях XIV в. отмечена взаимосвязь периодов строительной активности на территории резиденции новгородских архиепископов с городскими пожарами, что прослеживается и на других новгородских раскопах. Полученные в результате дендрохронологического исследования даты деревянных деталей каменных построек подтверждают средневековое происхождение руин митрополичьего дворца и являются дополнительным аргументом для идентификации храма Рождества Христова «на сенях».
The paper systemizes materials of the dendrochronological study of wood from excavations in the Novgorod Bishop’s court conducted in various years. The studies produced dendrochronological dates of 82 samples from houses and structures in the Bishop’s court and determined the construction time of 20 buildings of the 12th-19th centuries. The analysis of quantitative and chronological distribution of the dendrochronological dates enabled the author to justify the dating of the houses and structures as well as identify the periods of active construction in this part of the Detinets. The 14th century layers revealed linkage between the construction periods in the residence of the Novgorod bishops and city fires which is also observed in other Novgorod excavation trenches. The dates of the wood parts of stone buildings obtained by the dendrochronological study confirm that the ruins of the metropolitan’s place date to the medieval period and can serve as an additional argument for identifying of the Church of the Nativity of Christ in Seni.
Modeling the scattering of electromagnetic waves on structures in the form of a cube
Authors: Преображенский А.П. , Львович Я.Е. , Аветисян Т.В. , Преображенский Ю.П. 
Published: July 2024

На сегодняшний день среди различных прикладных задач в электродинамике можно отметить разработку различных подходов, направленных на оценку и исследование характеристик рассеяния различных электродинамических объектов. Среди них можно выделить трехмерные объекты, в составе которых выделяются плоские поверхности и угловые структуры. Их вклад в уровни электромагнитных полей в определенных направлениях может быть достаточно заметным. Для того, чтобы корректным образом осуществлять решение проблемы рассеяния характеристик рассеяния электромагнитных волн, требуется опираться на соответствующие методы. При этом необходимо минимизировать возможные ошибки, но рассматриваемую трехмерную задачу требуется решать за относительно небольшое время. В данной работе проводится построение методики, связанной с определением характеристик рассеяния структуры в виде куба. Это связано с тем, что подобные структуры входят в состав большого числа современных технических объектов, данное замечание необходимо учитывать в ходе их проектирования. Для решения поставленной задачи был выбран метод интегральных уравнений. Представлены результаты проведенного моделирования. Проводится сравнение с экспериментальными данными, показано, что решение сходится. Также проведено сравнение с характеристиками куба Гюйгенса.
To date, among the various applied tasks in electrodynamics, it is possible to note the development of various approaches aimed at evaluating and studying the scattering characteristics of various electrodynamic objects. Among them, three-dimensional objects can be distinguished, which include flat surfaces and angular structures. Their contribution to the levels of electromagnetic fields in certain directions can be quite noticeable. In order to correctly solve the problem of scattering of electromagnetic wave scattering characteristics, it is necessary to rely on appropriate methods. At the same time, it is necessary to minimize possible errors, but the three-dimensional problem in question needs to be solved in a relatively short time. In this paper, the construction of a technique related to the determination of the scattering characteristics of a structure in the form of a cube is carried out. This is due to the fact that such structures are part of a large number of modern technical facilities, this must be taken into account during their design. To solve this problem, the method of integral equations was chosen. The results of the simulation are presented. A comparison with experimental data is carried out, and it is shown that the solution converges. A comparison with the characteristics of the Huygens cube is also carried out.