bluuebunny/crossref_metadata_2025_split huggingface dataset:
Unique thallium mineralization in the fumaroles of Tolbachik volcano, Kamchatka Peninsula, Russia. III. Evdokimovite, Tl4(VO)3(SO4)5(H2O)5
Authors: Siidra Oleg I. , Vergasova Lidiya P. , Kretser Yuri L. , Polekhovsky Yuri S. , Filatov Stanislav K. , Krivovichev Sergey V. 
Published: March 2015

AbstractEvdokimovite, ideally Tl4(VO)3(SO4)5(H2O)5, was found in a fumarole of the 1st cinder cone of the North Breach of the Great Fissure Tolbachik volcano eruption of 1975–1976, Kamchatka Peninsula, Russia. Evdokimovite occurs as thin, colourless needles up to 0.09 mm long associated with shcherbinaite, pauflerite, bobjonesite, markhininite, karpovite and microcrystalline Mg, Al, Fe and Na sulfates. Evdokimovite is monoclinic, P21/n, a = 6.2958(14), b = 10.110(2), c = 39.426(11) Å , β = 90.347(6)º, V = 2509.4(10) Å3 and Z = 4 (from single-crystal diffraction data). The eight strongest lines of the powder X-ray diffraction pattern are (I/d/hkl): 57/9.793/011, 100/8.014/013, 26/6.580/006, 19/ 4.011/026, 29/3.621/118, 44/3.522/125, 19/3.010/036, 21/2.974/212. Chemical composition determined by the electron microprobe analysis is (wt.%): Tl2O 55.40, VO2 14.92, SO3 25.83, H2O 5.75, total 101.90. The empirical formula for evdokimovite calculated on the basis of (Tl + V + S) = 12 a.p.f.u. is Tl4.10V2.83S5.07H10.00O27.94. The simplified formula is Tl4(VO)3(SO4)5(H2O)5. The crystal structure was solved by direct methods and refined to R1 = 0.11 on the basis of 3660 independent observed reflections. V4+O6 octahedra and SO4 tetrahedra share common corners to form two types of vanadyl-sulfate chains, [(VO)(H2O)2(SO4)2]2– and [(VO)2(H2O)3(SO4)3]2–. Thallium atoms are located in between the chains. The structure can be described as a stacking of layers of two types, A and B. The A layer contains [(VO)2(H2O)3(SO4)3]2– chains and the Tl2 and Tl3 atoms, whereas the B layer contains [(VO)(H2O)2(SO4)2]2– chains and the Tl1 atoms. Stacking of the layers can be described as ...A’*BAA’B*A*..., where A and A’ denote A layers with opposite orientations of the [(VO)2(H2O)3(SO4)3]2– chains, and the A* and B* layers are rotated by 180º relative to the A and B layers, respectively. [(VO)2(H2O)3(SO4)3]2– chains are modulated and are arranged to form elliptical tunnels hosting disordered Tl(4), Tl(4A) and Tl(4B) sites. The new mineral is named in honour of Professor Mikhail Dmitrievich Evdokimov (1940–2010), formerly of the Department of Mineralogy, St Petersburg State University, for his contributions to mineralogy and petrology, and especially for teaching mineralogy to several generations of students at the University. Evdokimovite is the most complex V4+ sulfate known to date with structural information amounting to 1130 bits per unit cell, which places evdokimovite among minerals with the complexity of the vesuvianite group.
Crystal structure and revised chemical formula for burckhardtite, Pb2(Fe3+Te6+)[AlSi3O8]O6: a double-sheet silicate with intercalated phyllotellurate layers
Authors: Christy Andrew G. , Kampf Anthony R. , Mills Stuart J. , Housley Robert M. , Thorne Brent 
Published: March 2015

AbstractThe crystal structure of burckhardite from the type locality, Moctezuma, Sonora, Mexico, has been refined to R1 = 0.0362 and wR2 = 0.0370 for 215 reflections with I > 2σ(I). Burckhardtite is trigonal, space group P1m, with the unit-cell parameters a = 5.2566(5) Å , c = 13.0221(10) Å , V = 311.62(5) Å3 and Z = 1 for the ideal formula unit Pb2(Fe3+Te6+)[AlSi3O8]O6. There is no long-range order of (Fe3+, Te6+) or (Al3+, Si4+). New microprobe data were used to estimate site scattering factors, and Raman spectroscopic data showed no evidence of O–H stretching bands. Burckhardtite is not closely related to the micas, as supposed previously, but is a double-sheet silicate in which the aluminosilicate anion resembles that of minerals such as cymrite and kampfite. The [(Fe3+Te6+)O6]3– part of the structure is not bonded directly to the aluminosilicate layer, but forms a discrete anionic phyllotellurate layer that alternates with the [AlSi3O8]– double sheets. Similar phyllotellurate layers are known from several synthetic phases. In burckhardtite, Pb2+ cations intercalate between phyllosilicate and phyllotellurate layers, forming a Pb2[FeTeO6] module that is topologically similar to a slab of the structure of rosiaite, Pb[Sb2O6]. The crystal symmetry, structure, classification as a double-sheet silicate and chemical formula, including the determination of the 6+ valence of Te and absence of essential H2O, are all new findings for the mineral.
Thymic expression of a T-cell receptor targeting a tumor-associated antigen coexpressed in the thymus induces T-ALL
Authors: Cui Yongzhi , Onozawa Masahiro , Garber Haven R. , Samsel Leigh , Wang Ziyao , McCoy J. Philip , Burkett Sandra , Wu Xiaolin , Aplan Peter D. , Mackall Crystal L. 
Published: March 2015

Key PointsThymocyte signaling via a transgenic survivin-reactive TCR induced T-ALL with 100% penetrance. Thymic expression of signaling receptors targeting TAAs coexpressed in the thymus poses a risk for leukemogenesis.
Arsenic trioxide and all-trans retinoic acid target NPM1 mutant oncoprotein levels and induce apoptosis in NPM1-mutated AML cells
Authors: Martelli Maria Paola , Gionfriddo Ilaria , Mezzasoma Federica , Milano Francesca , Pierangeli Sara , Mulas Floriana , Pacini Roberta , Tabarrini Alessia , Pettirossi Valentina , Rossi Roberta , Vetro Calogero , Brunetti Lorenzo , Sportoletti Paolo , Tiacci Enrico , Di Raimondo Francesco , Falini Brunangelo 
Published: March 2015

Key Points
ATRA and ATO affect NPM1 protein levels in AML cells and induce cell growth inhibition and apoptosis. AML cells with mutated NPM1 respond to ATRA/ATO, and this might be exploited therapeutically.
Energy balance and fitness in adult survivors of childhood acute lymphoblastic leukemia
Authors: Ness Kirsten K. , DeLany James P. , Kaste Sue C. , Mulrooney Daniel A. , Pui Ching-Hon , Chemaitilly Wassim , Karlage Robyn E. , Lanctot Jennifer Q. , Howell Carrie R. , Lu Lu , Srivastava Deo Kumar , Robison Leslie L. , Hudson Melissa M. 
Published: March 2015

Key Points
Elimination of cranial radiation from therapy for childhood acute lymphoblastic leukemia has improved body-composition outcomes. Survivors of childhood acute lymphoblastic leukemia treated without cranial radiation remain at risk for impaired fitness.
Unexpected death within 72 hours of emergency department visit: were those deaths preventable?
Authors: Goulet Hélène , Guerand Victor , Bloom Benjamin , Martel Patricia , Aegerter Philippe , Casalino Enrique , Riou Bruno , Freund Yonathan 
Published: March 2015

Abstract
Introduction
We aimed to determine the rate of preventable death in patients who died early and unexpectedly following hospital admission from the emergency department (ED).

Methods
We conducted a retrospective multicenter study in four centers from the Paris metropolitan area. Inclusion criteria were medical patients who died in hospital within 72 hours of ED attendance and were not admitted to the intensive care unit (unexpected death). Exclusion criteria were limitations of care determined by treating physicians. The existence of a limitation of care decision was adjudicated by two independent chart abstractors. Preventable death was defined as death occurring as a result of medical error. For each selected patient with unexpected death, charts were examined for medical errors and rated on a 1 to 5 preventability scale (from very unlikely to very likely) for the preventability of the death. The primary endpoint was the likely preventable death, rated as 4 or 5 on the preventability scale.

Results
We retrieved 555 charts; 47 unexpected deaths were analysed; 24 (51%) were considered as preventable. There was a median number of medical errors of two. The most common process breakdowns were incorrect choice of treatment (47% of patients) and failure to order appropriate diagnostic tests (38% of patients). The most common medical error was a severe delay or absence of recommended treatment for severe sepsis, which occurred in 10 (42%) patients.

Conclusions
In our sample, more than half of unexpected deaths are related to a medical error, and could have been prevented.
Chaperoning of closed syntaxin-3 through Lys46 and Glu59 in domain 1 of Munc18 proteins is indispensable for mast cell exocytosis
Authors: Bin Na-Ryum , Jung Chang Hun , Kim Byungjin , Chandrasegram Prashanth , Turlova Ekaterina , Zhu Dan , Gaisano Herbert Y. , Sun Hong-Shuo , Sugita Shuzo 
Published: March 2015

ABSTRACT
Understanding how Munc18 proteins govern exocytosis is crucial because mutations of this protein cause severe secretion deficits in neuronal and immune cells. Munc18-2 has indispensable roles in the degranulation of mast cell, partly by binding and chaperoning a subset of syntaxin isoforms. However, the key syntaxin that, crucially, participates in the degranulation – whose levels and intracellular localization are regulated by Munc18-2 – remains unknown. Here, we demonstrate that double knockdown of Munc18-1 and Munc-2 in mast cells results in greatly reduced degranulation accompanied with strikingly compromised expression levels and localization of syntaxin-3. This phenotype is fully rescued by wild-type Munc18 proteins but not by the K46E, E59K and K46E/E59K mutants of Munc-18 domain 1, each of which exhibits completely abolished binding to ‘closed’ syntaxin-3. Furthermore, knockdown of syntaxin-3 strongly impairs degranulation. Collectively, our data argue that residues Lys46 and Glu59 of Munc18 proteins are indispensable for mediating the interaction between Munc18 and closed syntaxin-3, which is essential for degranulation by chaperoning syntaxin-3. Our results also indicate that the functional contribution of these residues differs between immune cell degranulation and neuronal secretion.
Synthesis and Application of a Novel Functionalized Magnetic Metal–Organic Framework Sorbent for Determination of Heavy Metal Ions in Fish Samples
Authors: Babazadeh Mirzaagha , Hosseinzadeh Khanmiri Rahim , Abolhasani Jafar , Ghorbani-Kalhor Ebrahim , Hassanpour Akbar 
Published: March 2015

Abstract
This work describes the synthesis and application of a novel magnetic metal–organic framework (MOF) [(Fe3O4-dipyridylamine)/MIL-101(Fe)] to preconcentrate trace amounts of Cd(II), Pb(II), Co(II), and Ni(II) ions and their determination by flame atomic absorption spectrometry. A Box–Behnken design was used to find the parameters affecting the preconcentration procedure through response surface methodology. Three factors including sorption time, amount of the magnetic sorbent, and pH of sample were selected as affecting factors in the sorption step, and four factors including type, volume and concentration of the eluent as well as the elution time were selected in the elution step for the optimization study. These values were obtained as 30 mg, 11 min, 6.5, EDTA + HNO3, 4.3 mL, 0.7 mol L−l EDTA in 0.13 mol L−l HNO3 solution, 14 min, for amount of the magnetic sorbent, sorption time, pH of sample, type, volume, and concentration of the eluent, and elution time, respectively. The limits of detection (LODs) were 0.13, 0.75, 0.3, and 0.5 ng mL−1 for Cd(II), Pb(II), Co(II), and Ni(II) ions, respectively. The relative standard deviations (RSDs) of the method were less than 9.2% for five separate batch experiments for the determination of 30 µg L−1 of Cd(II), Pb(II), Co(II), and Ni(II) ions. The sorption capacity of [(Fe3O4-dipyridylamine)/MIL-101(Fe)] was 188 mg g−1 for cadmium, 201 mg g−1 for lead, 173 mg g−1 for cobalt and 154 mg g−1 for nickel. Finally, the magnetic MOF nanocomposite was successfully applied to rapid extraction of trace amounts of heavy metal ions in fish samples.
The dynamic nature of alignment and variations in normal knees
Authors: Deep K. , Eachempati K. K. , Apsingi S. 
Published: March 2015

The restoration of knee alignment is an important goal during total knee arthroplasty (TKA). In the past surgeons aimed to restore neutral limb alignment during surgery. However, previous studies have demonstrated alignment to be dynamic, varying depending on the position of the limb and the degree of weight-bearing, and between patients. We used a validated computer navigation system to measure the femorotibial mechanical angle (FTMA) in 264 knees in 77 male and 55 female healthy volunteers aged 18 to 35 years (mean 26.2). We found the mean supine alignment to be a varus angle of 1.2° (standard deviation (sd) 4), with few patients having neutral alignment. FTMA differs significantly between males and females (with a mean varus of 1.7° (sd 4) and 0.4° (sd 3.9), respectively; p = 0.008). It changes significantly with posture, the knee hyperextending by a mean of 5.6°, and coronal plane alignment becoming more varus by 2.2° (sd 3.6) on standing compared with supine.Knee alignment is different in different individuals and is dynamic in nature, changing with different postures. This may have implications for the assessment of alignment in TKA, which is achieved in non-weight-bearing conditions and which may not represent the situation observed during weight-bearing.Cite this article: Bone Joint J 2015; 97-B:498–502
The natural history of primary anterior dislocation of the glenohumeral joint in adolescence
Authors: Roberts S. B. , Beattie N. , McNiven N. D. , Robinson C. M. 
Published: March 2015

The natural history of primary anterior dislocation of the glenohumeral joint in adolescent patients remains unclear and there is no consensus for management of these patients. The objectives of this study were to report the natural history of primary anterior dislocation of the glenohumeral joint in adolescent patients and to identify the risk factors for recurrent dislocation. We reviewed prospectively-collected clinical and radiological data on 133 adolescent patients diagnosed with a primary anterior dislocation of the glenohumeral joint who had been managed non-operatively at our hospital between 1996 and 2008. There were 115 male (86.5%) and 18 female patients (13.5%) with a mean age of 16.3 years (13 to 18) and a mean follow-up of 95.2 months (1 to 215). During follow-up, 102 (absolute incidence of 76.7%) patients had a recurrent dislocation. The median interval between primary and recurrent dislocation was ten months (95% CI 7.4 to 12.6). Applying survival analysis the likelihood of having a stable shoulder one year after the initial injury was 59% (95% CI 51.2 to 66.8), 38% (95% CI 30.2 to 45.8%) after two years, 21% (95% CI 13.2 to 28.8) after five years, and 7% (95% CI 1.1 to 12.9) after ten years. Neither age nor gender significantly predicted recurrent dislocation during follow-up. We conclude that adolescent patients with a primary anterior dislocation of the glenohumeral joint have a high rate of recurrent dislocation, which usually occurs within two years of their initial injury: these patients should be considered for early operative stabilisation. Cite this article: Bone Joint J 2015;97-B:520–6.
Common contra-indications and interactions of drugs in orthopaedic practice
Authors: Shabani F. , Farrier A. J. , Krishnaiyan R. , Hunt C. , Uzoigwe C. E. , Venkatesan M. 
Published: March 2015

Drug therapy forms an integral part of the management of many orthopaedic conditions. However, many medicines can produce serious adverse reactions if prescribed inappropriately, either alone or in combination with other drugs. Often these hazards are not appreciated. In response to this, the European Union recently issued legislation regarding safety measures which member states must adopt to minimise the risk of errors of medication.In March 2014 the Medicines and Healthcare products Regulatory Agency and NHS England released a Patient Safety Alert initiative focussed on errors of medication. There have been similar initiatives in the United States under the auspices of The National Coordinating Council for Medication Error and The Joint Commission on the Accreditation of Healthcare Organizations. These initiatives have highlighted the importance of informing and educating clinicians.Here, we discuss common drug interactions and contra-indications in orthopaedic practice. This is germane to safe and effective clinical care.Cite this article: Bone Joint J 2015;97-B:434–41.
Les acteurs de l’hégémonie hispanique, du monde à la péninsule Ibérique
Authors: Ibáñez José Javier Ruiz 
Published: March 2015

Résumé
La compréhension de la formation et de l’hégémonie de la Monarchie espagnole aux XVIe et XVIIe siècles ne peut pas se faire sans l’étude des phénomènes sociaux et culturels sur lesquels elle s’est établie. L’expansion du pouvoir espagnol et portugais a déclenché des processus politiques et sociaux qui ont eu comme protagonistes les populations locales d’Europe, d’Afrique, d’Asie et des Amériques. Bien qu’elles aient été incorporées, de gré ou de force, ou qu’elles aient été voisines du pouvoir ibérique, leurs tensions locales et leurs choix politiques ont fini par devenir décisifs dans la configuration du pouvoir espagnol et son évolution. La politique locale devient ainsi un objet d’analyse du global. L’histoire de la Monarchie incorpore les processus violents de sa formation, son polycentrisme, ses rapports avec le reste du monde et, surtout, met au premier plan les acteurs ordinaires : ceux qui l’ont adoptée et ceux qui l’ont combattue.
Discontinuités spatiales et pastoralisme nomade en Asie intérieure au tournant des XIXe et XXe siècles
Authors: Ferret Carole 
Published: March 2015

RésuméLe pastoralisme, activité traditionnelle des peuples turco-mongols de Sibérie et d’Asie centrale, a créé des discontinuités qui ont structuré l’espace apparemment homogène de la steppe. Par leurs parcours de nomadisation stables et réguliers, les éleveurs découpent l’espace en pâtures saisonnières, appréciant la qualité des terres en fonction des besoins du bétail et relativement à une saison donnée. L’analyse du fonctionnement des diverses formes de pastoralisme nomade pratiquées au tournant des XIXeet XXesiècles par les Turkmènes, les Kazakhs, les Kirghizes, les Khakasses, les Bouriates, les Touvas, les Mongols et les Iakoutes permet d’affiner ce modèle et d’identifier plusieurs types de nomadisme, suivant des critères fondés sur le mode de résidence, la forme des parcours, la fréquence et l’amplitude des nomadisations. Interrogeant plusieurs idées reçues, l’auteur montre que, si le bétail est bien le moteur du nomadisme, il n’existe pas de corrélation univoque, synchronique ni diachronique, entre le degré de mobilité des hommes et celui des espèces élevées. Pastoralisme et nomadisme sont deux phénomènes liés, mais ils ne peuvent être confondus.
Gouvernement et pénitence
Authors: Dejoux Marie 
Published: March 2015

RésuméEn 1247, avant la croisade, et jusqu’à sa mort en 1270, Louis IX fit recueillir les plaintes de ses sujets afin de réparer les torts de son administration. Pénitentielles, ces enquêtes étaient aussi des instruments de gouvernement, comme en attestent les enquêtes de restitution des usures juives. Les saisies générales des biens des créanciers juifs avaient rendu Louis IX coupable d’un recel d’autant plus peccamineux qu’il provenait d’une activité condamnée par l’Église et par le roi en personne : l’usure. Au nom de sa souveraineté sursesjuifs – les « juifs du roi » – et pour le salut de son âme, le roi entendit publiquement rendre à ses sujets ces biens mal acquis. La restitution des usures juives est une entreprise deconversionmultiple : Louis IX ne restitue qu’une partie des biens des juifs et convertit le reste à un usage pieux, la croisade. En rendant, il transforme également en salut ses exactions et tourne à son avantage le rejet que pouvaient inspirer les créanciers juifs. Ces enquêtes incarnent donc un art de gouverner singulier, mêlant contrainte et consentement, souveraineté et scrupule religieux : le « moment saint Louis ».
L’esprit tue aussi
Authors: Kriegel Maurice 
Published: March 2015

Résumé
Dans son livre, David Nirenberg donne de l’antijudaïsme une définition très englobante : il ne s’agit pas de l’hostilité à l’égard d’une religion, d’une culture ou d’une population – le judaïsme et les Juifs –, mais de l’appréhension critique d’un ensemble de notions que représente le « judaïsme », à travers laquelle les porteurs de cet antijudaïsme cherchent à se situer dans le monde et à donner sens à leur action. Pour D. Nirenberg, cet antijudaïsme a constitué l’un des principaux outils à l’aide desquels l’édifice de la pensée occidentale a été construit ; il s’est nourri des débats internes au christianisme d’abord, à la culture européenne ensuite, sans confrontation directe avec les Juifs ; et l’antisémitisme correspond au cas particulier dans lequel le discours de l’antijudaïsme est appliqué aux Juifs concrets. Cet article, qui discute ces thèses, se propose deux objectifs : calibrer autrement la part de la tradition de l’antijudaïsme dans l’institution des discours et de l’imaginaire « occidentaux » ; souligner qu’à chaque étape – dans l’Antiquité tardive, au Moyen Âge et au début des temps modernes, depuis les Lumières – l’évolution des attitudes envers les Juifs est d’abord fonction de changements dans les rapports qu’entretient la société majoritaire avec les Juifs réels.
De l’antijudaïsme à l’antisémitisme, et à rebours
Authors: Englund Steven 
Published: March 2015

Résumé
Le paradigme actuellement dominant dans les recherches sur l’antisémitisme correspond à la vision proposée dans l’Encyclopaedia Britannica (1910) : « L’antisémitisme est une question exclusivement politique et européenne. » Si cette conception a donné lieu à des études empiriques majeures, elle recèle des problèmes conceptuels, dont le moindre n’est pas qu’elle se contente de recycler l’idée que les antisémites se font d’eux-mêmes, à savoir que leur préoccupation n’est pas religieuse mais liée à des considérations objectives. Le présent article démontre en quoi les discours déployés et l’attrait politique de l’antisémitisme doivent être distingués de sa réception et de sa compréhension sociale ; il suggère que le « nouvel » Antisemitismus, tel qu’il a été compris dans les faits, est d’une nature différente de ce qui avait été l’intention de ses partisans. Ce soi-disant « nouvel antisémitisme » implique l’influence omniprésente, forte et néanmoins subtile d’une ancienne trinité d’éléments « spirituels » sous-jacents : la religion institutionnalisée (Olaf Blaschke) ; le religieux dans un sens diffus, ou « métabolisé » (Marcel Gauchet) ; la religiosité comme posture personnelle, qui guide les antisémites en tant qu’individus (Gavin Langmuir). Ces dimensions ont imprégné les positions et les désaccords d’un antisémitisme ordinaire agissant sur le plan politique, social, économique, culturel et « racial ». Elles véhiculent son message, jusque dans les strates intellectuelles et émotionnelles les plus profondes, auprès de populations qui ont baigné dans l’antijudaïsme pendant des siècles (David Nirenberg). D. Nirenberg ayant analysé l’imaginaire social de l’antijudaïsme, il reste à voir où et comment il rejoint et sous-tend discrètement l’antisémitisme politique.
What is the significance of the establishment of the Slovenian Theatre Institute?
Authors: Arhar Nika 
Published: March 2015

Abstract
Already back in the 1960s, Dušan Moravec was planning the functioning of the Slovenian National Theatre Museum [Slovenski gledališki muzej] as a museological and, more broadly, research-based activity; yet, his vision of an institute did not take off while he was in charge of the museum. In February 2014, upon the initiative of the museum, its director and experts in the field, the Government of the Republic of Slovenia ratified the decision to restructure SGM and to establish the Slovenian Theatre Institute; however, this is supposed to transpire at the time of funding cuts in all areas with no financial and personnel consolidation. We are right to ask then: what does the establishment of the institute mean in the given circumstances, especially if we take into account the fact that SGM has been working in disorganised circumstances ever since its inception?.