bluuebunny/crossref_metadata_2025_split huggingface dataset:
50 ans de service public pour les politiques et l’organisation des services de psychiatrie communautaire au Québec
Authors: Lesage Alain 
Published: October 2015

Cet essai, rédigé en deux articles compagnons (Partie I & II), est destiné mettre en valeur le service public de psychiatres du Département de psychiatrie de l’Université de Montréal ayant oeuvré au niveau du ministère de la Santé et des Services sociaux (MSSS) pour les politiques de désinstitutionnalisation et l’organisation des services de psychiatrie communautaire pour les personnes avec des troubles mentaux graves. Il s’agit des Drs Camille Laurin, Denis Lazure, Arthur Amyot, Luc Blanchet et André Delorme.
Dans cette seconde partie, la période 2003-2015 sera couverte. Elle marque la fin du Comité de la santé mentale du Québec (1971-2003), et ses travaux féconds interdisciplinaires. 2003, c’est l’entrée au ministère du Dr André Delorme qui y détient sans doute un des records de longévité, servant depuis 2003 à la Direction de la santé mentale transférée sous la nouvelle Direction des affaires médicales et universitaires du MSSS également créée en 2003.
Cette phase voit l’émergence depuis le modèle de psychiatrie communautaire d’une approche différentiée, les cliniques spécialisées ou l’approche par programme-clientèle. Mais ce dernier modèle ne dispose pas des ressources nécessaires pour s’étendre et éviter des difficultés d’accès. L’essai conclut avec une discussion sur l’impact de la toute nouvelle gouvernance du système de la santé et des services sociaux du Québec, la loi 10. En simplifiant le système de santé en deux lignes (soins primaires dans les bureaux des médecins de famille, avec soutien infirmier et social ; soins spécialisés par le personnel des centres intégrés de santé et de services sociaux [CISSS]), il sera soutenu qu’il y a des opportunités pour un financement plus équitable et un système plus équilibré de santé mentale au Québec.
L’Institut Philippe Pinel et le Département de psychiatrie de l’Université de Montréal : des parcours intriqués
Authors: Bouchard Anne-Marie , Morissette Louis , Millaud Fédéric 
Published: October 2015

L’Institut Philippe-Pinel (IPPM) et le Département de psychiatrie de l’Université de Montréal, qui célèbrent tous deux leurs 50 ans, ont des parcours intriqués et une longue histoire de collaboration. Dès sa conception d’ailleurs à partir de l’Hôpital psychiatrique de Bordeaux, l’IPPM se destinait à devenir un lieu de formation et d’enseignement dans le giron de l’Université de Montréal.
Unique dans sa mission d’offrir des soins psychiatriques de pointe et des évaluations médico-légales à une clientèle présentant un risque élevé de violence, l’Institut Pinel a aussi su, au fil des ans, faire sa marque dans l’enseignement aux résidents et stagiaires, dans l’organisation de colloques nationaux et internationaux, dans la recherche et la publication d’ouvrages reconnus dans le champ de la psychiatrie légale.
Avec à sa tête des directeurs généraux qui ont tous été psychiatres de formation, l’Institut a de tout temps contribué largement à la vie universitaire, par un engagement marqué de ses psychiatres au sein du Département. Avec l’arrivée de la surspécialité en psychiatrie légale, cet engagement et ce rayonnement ne peuvent que se poursuivre.
Qu’est-ce qu’une institution psychiatrique ?
Authors: Kapsambelis Vassilis 
Published: October 2015

Une institution psychiatrique se définit comme un groupe de professionnels de compétences différentes, se réunissant autour du projet d’accueillir et de soigner des personnes ayant des troubles psychiques. Cette définition est examinée dans ses différentes dimensions : groupe, et donc collectif constituant un organisme vivant ; complémentarité ; élaboration d’un ensemble cohérent et sens de la notion de cohérence ; actions communes et objet de cette pulsionnalité collective : le patient ou ses soins. Les questions du lieu de l’institution, et aussi de la nature du trouble psychique, sont également évoquées.
La solidarité et la justice reconsidérées
Authors: Haker Hille , Côté Richard 
Published: October 2015

En commençant par déplorer l’absence de place pour la solidarité dans l’interprétation de la « justice de marché » au xxie siècle, l’article propose une autre voie, soit la relation dialectique entre la justice et la solidarité. Alors que la justice met l’accent sur l’« égalité » pour tous, la solidarité s’attarde surtout sur la « différence » et la diversité. Le pont entre les deux concepts peut être trouvé dans les récentes réinterprétations de la théorie de la reconnaissance, qui touche les sphères privée, sociale et politique. L’article préconise toutefois une approche critique, qui prend le manque de reconnaissance, plutôt que la reconnaissance, comme point de départ. L’éthique en général et l’éthique chrétienne en particulier doivent prêter attention aux expériences et aux récits des personnes qui semblent invisibles et inaudibles dans les systèmes de justice fondés sur le mérite et les accomplissements, et ce, dans le but d’identifier les violations de droits aussi bien que les pratiques d’exclusion subies par ces personnes. En se préoccupant d’abord des expériences réelles d’injustice au lieu de la théorie normative de la justice, la relation dialectique entre la justice et la solidarité devient claire : la solidarité révèle non seulement le fossé entre la théorie et la pratique, ou l’inévitable côté aveugle de la justice, mais elle s’affiche aussi clairement en faveur des personnes souffrant d’injustice. La solidarité est orientée vers l’action. Elle fait pression sur les institutions pour qu’elles deviennent justes, tout en prônant des changements pour ceux et celles qui souffrent le plus d’injustice, et tout en accompagnant ces personnes. Par ailleurs, la solidarité critique mais aussi partisane nécessite la vision impartiale et égalitaire d’une justice en tant que critique d’une idéologie potentielle qui est liée à un concept identitaire et à une politique identitaire.
La charismatisation de la religion
Authors: Lucchetti Bingemer Maria Clara 
Published: October 2015

Dans le monde d’aujourd’hui, nous voyons, d’un côté, que de nombreuses personnes perdent le sens transcendantal de leur vie et abandonnent les pratiques religieuses et, de l’autre côté, un nombre significatif de catholiques est en train d’abandonner l’Église pour entrer dans d’autres groupes religieux. Ce texte essaie d’examiner le « cas » brésilien. Nous prendrons comme cadre les chiffres fournis par le dernier recensement de 2010 sur le champ religieux au Brésil, récemment divulgué. Nous risquerons alors quelques interprétations à partir de ce recensement et finirons par identifier certains défis qui apparaissent pour la théologie et la pastorale au Brésil. Nous finirons notre réflexion par quelques observations sur les changements apportés par le nouveau pontificat du pape François, qui permettent d’espérer certains changements à court et moyen termes dans l’Église brésilienne et tout le continent latino-américain.
Dans la trace du bélier
Authors: Ombrosi Orietta 
Published: October 2015

Dans cet article, je cherche à envisager un certain judaïsme de Derrida ou ce qui reste du judaïsme dans sa pensée, en suivant les traces qu’un animal — le bélier — laisse dans les écrits du philosophe. En effet, les deux sujets, celui de l’animalité et celui de la judéité se croisent et se côtoient précisément autour de cette figure animale, qui n’est pas pourtant une figure ou une métaphore uniquement. Je choisis donc de suivre le bélier pour suivre l’adresse de Derrida qui appelle les philosophes à répondre philosophiquement de l’« animal », c’est-à-dire à s’interroger de la « question animale », d’une part ; d’autre part et en même temps, je le suis pour voir les moments essentiels les plus représentatifs dans le rituel juif, où cet animal se montre, et pour discerner ce qu’il révèle justement en relation au judaïsme tel que le philosophe Derrida l’a vécu ou conçu. L’article se divise donc en trois grandes parties qui correspondent aux trois scènes où le bélier, les béliers plutôt, fait/font son/leur apparition : la première scène est celle du bélier de la prière, se montrant et se cachant dans le tallith ; ensuite, la scène sacrificielle par excellence (Gen 22) où le bélier du sacrifice est sacrifié par Abraham ; enfin, le bélier eschatologique, ainsi nommé parce qu’il est celui qui porte ou porterait l’autre, dans une dimension eschatologique à venir, selon une des dernières lectures derridiennes de Paul Celan, donnée dans le livre Béliers.
The impact of scaling‐up combination antiretroviral therapy on patterns of mortality among HIV‐positive persons in British Columbia, Canada
Authors: Lima Viviane Dias , Eyawo Oghenowede , Ma Huiting , Lourenço Lillian , Chau William , Hogg Robert S , Montaner Julio SG 
Published: October 2015

IntroductionDespite the tremendous improvements in survival, some groups of people living with HIV (PLHIV) continue to have lower survival rates than the overall HIV‐positive population. Here, we characterize the evolving pattern of mortality among PLHIV in British Columbia since the beginning of the expansion of antiretroviral treatment in 2003.MethodsThis retrospective cohort study included 3653 individuals ≥20 years old, who enrolled on treatment between January 1, 2003, and December 31, 2012, and were followed until December 31, 2013. All‐cause mortality rates and standardized mortality ratios (SMRs) were calculated to compare mortality outcomes of PLHIV to the general population. Abridged life tables were constructed to estimate the life expectancy at age 20 years for PLHIV.ResultsThe overall crude mortality rate was 28.57 per 1000 person‐years, the SMR was 3.22 and the life expectancy was 34.53 years. Interestingly, if we considered only individuals alive after the first year, the life expectancy increased to 48.70 years (41% increase). The SMRs for males and females decreased over time. Although females had higher SMRs in 2003 to 2008, this difference no longer existed in 2009 to 2011. There were also important differences in mortality outcomes for different clinical and demographical characteristics.ConclusionsMortality outcomes of PLHIV who initiated antiretroviral treatment have dramatically improved over the last decade. However, there is still room for improvement and multilateral efforts should continue to promote early, sustained engagement of PLHIV on treatment so that the impact of treatment can be fully realized.
A Self‐Standing High‐Performance Hydrogen Evolution Electrode with Nanostructured NiCo2O4/CuS Heterostructures
Authors: An Li , Huang Liang , Zhou Panpan , Yin Jie , Liu Hongyan , Xi Pinxian 
Published: October 2015

An efficient self‐standing 3D hydrogen evolution cathode has been developed by coating nickel cobaltite (NiCo2O4)/CuS nanowire heterostructures on a carbon fiber paper (CFP). The obtained CFP/NiCo2O4/CuS electrode shows exceptional hydrogen evolution reaction (HER) performance and excellent durability in acidic conditions. Remarkably, as an integrated 3D hydrogen‐evolving cathode operating in acidic electrolytes, CFP/NiCo2O4/CuS maintains its activity more than 50 h and exhibits an onset overpotential of 31.1 mV, an exchange current density of 0.246 mA cm−2, and a Tafel slope of 41 mV dec−1. Compared to other non‐Pt electrocatalysts reported to date, CFP/NiCo2O4/CuS exhibits the highest HER activity and can be used in HER to produce H2 with nearly quantitative faradaic yield in acidic aqueous media with stable activity. Furthermore, by using CFP/NiCo2O4/CuS as a self‐standing electrode in a water electrolyzer, a current density of 18 mA cm−2 can be achieved at a voltage of 1.5 V which can be driven by a single‐cell battery. This strategy provides an effective, durable, and non‐Pt electrode for water splitting and hydrogen generation.
Benzyl Esters of Vegetable Oils as Processing Oil in Carbon Black–Filled SBR Compounding: Chemical Modification, Characterization, and Performance
Authors: Boontawee Hasleena , Nakason Charoen , Kaesaman Azizon , Thitithammawong Anoma , Chewchanwuttiwong Sopa 
Published: October 2015

ABSTRACTThree different types of benzyl ester were synthesized from vegetable oils (i.e., coconut oil, palm oil, and soybean oil). They were then utilized in styrene butadiene rubber (SBR) compound reinforced with carbon black. First, the benzyl esters were investigated by varying the molar ratio of fatty acids in vegetable oil to benzyl alcohol, the catalyst concentration, the reaction time, and the reaction temperature, observing the yield of benzyl ester. Then SBR was compounded with the benzyl esters, observing cure characteristics, mechanical properties, and morphologies of the SBR compounds, with the control compound containing conventional aromatic oil. The highest 96% yield of benzyl ester was obtained with palm oil fatty acid. Furthermore, the benzyl ester oils consumed less energy during processing but gave comparable carbon black dispersion, in comparison with the conventional aromatic oil.
Individual, occupational, and workplace correlates of occupational health and safety vulnerability in a sample of Canadian workers
Authors: Lay A. Morgan , Saunders Ron , Lifshen Marni , Breslin Curtis , LaMontagne Anthony , Tompa Emile , Smith Peter 
Published: October 2015

ObjectiveTo describe OH&S vulnerability across a diverse sample of Canadian workers.MethodsA survey was administered to 1,835 workers employed more than 15 hrs/week in workplaces with at least five employees. Adjusted logistic models were fitted for three specific and one overall measure of workplace vulnerability developed based on hazard exposure and access to protective OH&S policies and procedures, awareness of employment rights and responsibilities, and workplace empowerment.ResultsMore than one third of the sample experienced some OH&S vulnerability. The type and magnitude of vulnerability varied by labor market sub‐group. Younger workers and those in smaller workplaces experienced significantly higher odds of multiple types of vulnerability. Temporary workers reported elevated odds of overall, awareness‐ and empowerment‐related vulnerability, while respondents born outside of Canada had significantly higher odds of awareness vulnerability.ConclusionKnowing how labor market sub‐groups experience different types of vulnerability can inform better‐tailored primary prevention interventions. Am. J. Ind. Med. 59:119–128, 2016. © 2015 The Authors. American Journal of Industrial Medicine Published by Wiley Periodicals, Inc.
Platelet lysate and adipose mesenchymal stromal cells on silk fibroin nonwoven mats for wound healing
Authors: Theodora Chlapanidas , Sara Perteghella , Silvio Faragò , Alessandra Boschi , Giuseppe Tripodo , Barbara Vigani , Barbara Crivelli , Sabrina Renzi , Silvia Dotti , Stefania Preda , Mario Marazzi , Maria Luisa Torre , Maura Ferrari 
Published: October 2015

ABSTRACTIn this work platelet lysate (PL) and adipose‐derived mesenchymal stromal cells (ASCs) seeded on nonwoven fibroin mats were in vitro and in vivo evaluated for tissue regenerative applications. Nonwoven mats obtained by a large scale water entanglement technique were characterized for their physico‐chemical properties. Results indicated a high purity of fibroin fibers, their stability after sterilization process and appropriate technological properties suitable for tissue engineering. Moreover, the scaffolds in vitro supported adhesion and migration of ASCs and the presence of PL improved the cell proliferation. The products were then applied on epithelial/dermal wounds carried out on the dorsal surface of rabbit: the skin reparative process was solved in 9 days, with a completely restitutio ad integrum of the epithelium in animals treated with PL alone; ASCs did not further improve the wound healing. © 2015 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2016, 133, 42942.
Enhanced stem cell‐derived cardiomyocyte differentiation in suspension culture by delivery of nitric oxide using S‐nitrosocysteine
Authors: Hodge Alexander J. , Zhong Juming , Lipke Elizabeth A. 
Published: October 2015

ABSTRACTThe development of cell‐based treatments for heart disease relies on the creation of functionally mature stem cell‐derived cardiomyocytes employing in vitro culture suspension systems, a process which remains a formidable and expensive endeavor. The use of nitric oxide as a signaling molecule during differentiation has demonstrated the potential for creating increased numbers of spontaneously contracting embryoid bodies in culture; however, the effects of nitric oxide signaling on the function and maturation of stem cell‐derived cardiomyocytes is not well understood. In this study, the effects of nitric oxide on mouse embryonic stem cell‐derived cardiomyocyte contractile activity, protein, and gene expression, and calcium handling were quantified. Embryoid bodies (EBs) formed using the hanging drop method, were treated with the soluble nitric oxide donor S‐nitrosocysteine (CysNO) over a period of 18 days in suspension culture and spontaneous contractile activity was assessed. On day 8, selected EBs were dissociated to form monolayers for electrophysiological characterization using calcium transient mapping. Nitric oxide treatment led to increased numbers of stem cell‐derived cardiomyocytes (SC‐CMs) relative to non‐treated EBs after 8 days in suspension culture. Increased incidence of spontaneous contraction and frequency of contraction were observed from days 8–14 in EBs receiving nitric oxide treatment in comparison to control. Expression of cardiac markers and functional proteins was visualized using immunocytochemistry and gene expression was assessed using qPCR. Cardiac‐specific proteins were present in both CysNO‐treated and control SC‐CMs; however, CysNO treatment during differentiation significantly increased βMHC gene expression in SC‐CMs relative to control SC‐CMs. Furthermore, increased calcium transient velocity and decreased calcium transient duration was observed for CysNO‐treated SC‐CMs in comparison to control SC‐CMs. Soluble nitric oxide donors, including S‐nitrosocysteine, have advantages over other bioactive molecules for use in scalable culture systems in driving cardiac differentiation, since they are inexpensive and the diffusivity of nitric oxide is relatively high. By enabling maintenance of spontaneous contraction in suspension culture and progressing electrophysiological function of resulting SC‐CMs toward a more mature phenotype, long‐term application of S‐nitrosocysteine was shown to be beneficial during cardiac differentiation. Taken together, these results demonstrate the efficiency of nitric oxide as a signaling compound, with implications in the improvement of pluripotent stem cell‐derived cardiomyocyte maturation in large‐scale culture systems. Biotechnol. Bioeng. 2016;113: 882–894. © 2015 Wiley Periodicals, Inc.
Bilateral renal lymphoma: rapid recovery from an acute kidney injury after open renal biopsy
Authors: Mitome Taku , Furuya Kazuhiro , Imano Masashi , Osaka Kimito , Yokomizo Yumiko , Hayashi Narihiko , Nakaigawa Noboru , Yamanaka Shoji , Yao Masahiro 
Published: October 2015

Key Clinical MessageRenal lymphoma as an initial lesion is relatively rare. Bilateral renal lymphoma frequently presents as acute kidney injury. With systematic chemotherapy for the lymphoma, patients usually recover their kidney function. However, in the case we describe here, the patient's kidney function recovered greatly after an open renal biopsy. Here, we review and discuss this unique case.
Three‐Tier Hierarchical Clusters of Carbon‐Coated Li4Ti5O12 Single Crystals as High‐Power and High‐Energy Anodes for Lithium‐Ion Batteries
Authors: Bai Hongwei , Zan Xiaoli , Liu Zhaoyang , Sun Darren Delai 
Published: October 2015

AbstractA novel three‐tier hierarchical cluster lithium‐ion battery (LIB) anode is reported here, consisting of 1) carbon‐coated Li4Ti5O12 crystals as the first nano‐tier (ca. 10 nm) for high‐rate capability; 2) submicron spheres consisting of Li4Ti5O12 crystals as the second submicron tier (100–300 nm), facilitating electrolyte infiltration and Li+ diffusion; and 3) clusters comprising Li4Ti5O12 spheres as the third micron‐sized tier (1–2 μm) to increase the packing density of active materials for high‐power LIBs. The submicron tier acts as a transition zone between the nano‐tier and micro‐tier to further benefit Li+ diffusion, electrolyte infiltration, and electron transport. The carbon coating on Li4Ti5O12 forms a uniform and continuous conductive network for fast electron transport and Li+ diffusion to address the low electronic conductivity obstacle of the Li4Ti5O12 anode. The three‐tier hierarchical clusters maximize the close contact between the electrolytes and the active materials for excellent electrochemical performance.
Analysis of Proton NMR in Hydrogen Bonds in Terms of Lone‐Pair and Bond Orbital Contributions
Authors: Sutter Kiplangat , Aucar Gustavo A. , Autschbach Jochen 
Published: October 2015

AbstractNMR spectroscopic parameters of the proton involved in hydrogen bonding are studied theoretically. The set of molecules includes systems with internal resonance‐assisted hydrogen bonds, internal hydrogen bonds but no resonance stabilization, the acetic acid dimer (AAD), a DNA base pair, and the hydrogen succinate anion (HSA). Ethanol and guanine represent reference molecules without hydrogen bonding. The calculations are based on zero‐point vibrationally averaged molecular structures in order to include anharmonicity effects in the NMR parameters. An analysis of the calculated NMR shielding and J‐coupling is performed in terms of “chemist’s orbitals”, that is, localized molecular orbitals (LMOs) representing lone‐pairs, atomic cores, and bonds. The LMO analysis associates some of the strong de‐shielding of the protons in resonance‐assisted hydrogen bonds with delocalization involving the π‐backbone. Resonance is also shown to be an important factor causing de‐shielding of the OH protons for AAD and HSA, but not for the DNA base pair. Nitromalonamide (NMA) and HSA have particularly strong hydrogen bonds exhibiting signs of covalency in the associated J‐couplings. The analysis results show how NMR spectroscopic parameters that are characteristic for hydrogen bonded protons are influenced by the geometry and degree of covalency of the hydrogen bond as well as intra‐ and intermolecular resonance.
Electrochemical Fluorographane: Hybrid Electrocatalysis of Biomarkers, Hydrogen Evolution, and Oxygen Reduction
Authors: Gusmão Rui , Sofer Zdeněk , Šembera Filip , Janoušek Zbyněk , Pumera Martin 
Published: October 2015

AbstractFluorographane (C1HxF1−x+δ)n is a new member of the graphene family that exhibits hydrophobicity and a large band gap that is tunable based on the level of fluorination. Herein, sensing and energy applications of fluorographane are reported. The results reveal that the carbon‐to‐fluoride ratio of fluorographane has a great impact on the electrochemical performance of the materials. Lowered oxidation potentials for ascorbic and uric acids, in addition to a catalytic effect for hydroquinone and dopamine redox processes, are obtained with a high fluoride content. Moreover, fluorographane, together with residual copper‐ and nickel‐based doping, acted as a hybrid electrocatalyst to promote hydrogen evolution and oxygen reduction reactions with considerably lower onset potentials than those of graphane (starting material), which makes this a promising material for a broad range of applications.