bluuebunny/crossref_metadata_2025_split huggingface dataset:
Emotions in supermarket brand choice
Authors: Spanjaard Daniela , Young Louise , Freeman Lynne 
Published: June 2014

Purpose
– The purpose of this article is to show how the application of multiple qualitative methods reveals insights into grocery shopping that cannot be captured via traditional survey methods.

Design/methodology/approach
– A mixed-method approach was applied where the results of one technique provided the guidelines for the next as a way to understand how decisions are made within a grocery store. A mail survey started the process which subsequently presented input for the focus group, leading to videographic observations, depth interviews and consumer diaries.

Findings
– The results show that many decisions in the grocery store are not driven by the store environment but rather by emotional connections to the brand. This suggests that using behavioral and attitudinal surveys to understand this perspective may not adequately capture important aspects of grocery buying. Instead, consideration must be given to alternative methods which offer the shopper freedom to discuss what is important to them in terms of product selection.

Research limitations/implications
– This study is unique in applying multiple qualitative methods to an environment that is often overlooked as a source for meaningful insights into consumer decisions. The ability to use methods such as videography and self-assessment provides consequential reasons behind consumer behaviour rather than just statistical measurements of this.

Practical implications
– The results make a note of caution for retailers. Radical changes to brand offerings (e.g. deleting lines) and accessibility to preferred products (e.g. out of stocks, store layouts) runs the risk of potentially isolating regular customers. Our research shows that when a favorite product is not available, a substitute is not likely. Instead respondents tend to go to another store that does stock their brand, or they buy a smaller, cheaper product to “make do” until the next shop. Neither option is a good outcome for the consumer, the manufacturer or the store.

Originality/value
– This study will show that for grocery buying, not all decisions are rational where the use of available information is what drives the final brand choice. Instead, consumers display evidence of emotion that one research method in isolation is unlikely to adequately capture.
No association of atherosclerosis with digital ulcers in Japanese patients with systemic sclerosis: Evaluation of carotid intima‐media thickness and plaque characteristics
Authors: Motegi Sei‐ichiro , Toki Sayaka , Hattori Tomoyasu , Yamada Kazuya , Uchiyama Akihiko , Ishikawa Osamu 
Published: June 2014

AbstractPatients with systemic sclerosis (SSc) usually develop Raynaud's phenomenon, persistent digital ischemia and sometimes develop digital ulcers (DU). Several studies have reported an association of carotid artery atherosclerosis with SSc by evaluating carotid intima‐media thickness (IMT) in SSc patients. However, none of those studies analyzed the association between DU and carotid artery atherosclerosis in SSc patients. We examined the association of carotid artery atherosclerosis with digital ulcers by comparing SSc patients with (n = 48, 29.5%) and without (n = 206, 70.5%) DU. The demographic and clinical features of the SSc patients showed that young age, male sex, anti‐topoisomerase I antibody positivity, severe skin sclerosis, interstitial lung disease complication and cardiac involvements were significantly prevalent in patients with DU. In addition, diffuse cutaneous type, anti‐RNA polymerase III antibody positivity and severe skin sclerosis are more frequent in SSc patients with DU at the extensor surface of joints than SSc patients with DU at the digital tip. There were no differences in serum lipid level, carotid IMT or plaque score between SSc patients with and without DU, suggesting that atherosclerotic changes are not primarily involved in the development of DU.
Remission period in psoriasis after multiple cycles of narrowband ultraviolet B phototherapy
Authors: Ryu Hyeong Ho , Choe Yun Seon , Jo Seongmoon , Youn Jai Il , Jo Seong Jin 
Published: June 2014

AbstractThe aim of this study was to investigate the duration of remission periods in psoriasis after narrowband ultraviolet B (NB‐UVB) phototherapy, especially during multiple cycles of treatment. We analyzed 63 patients (101 cases) demonstrating marked improvement after NB‐UVB phototherapy. The remission period was defined as the duration of time from the end of phototherapy until treatment using either phototherapy or systemic treatments was required again. It was found that an age of 60 years or older, history of systemic therapy within 6 months and three or more phototherapy cycles were significantly associated with shorter remission periods. Furthermore, multivariate analysis confirmed that three or more phototherapy cycles (odds ratio [OR], 4.0; 95% confidence interval [CI], 1.73–9.33; P = 0.001) and a history of systemic therapy (OR, 2.2; 95% CI, 1.27–3.95; P = 0.005) were independently associated with the shorter remission period. In conclusion, when planning NB‐UVB phototherapy for psoriatic patients who have undergone multiple phototherapy cycles, clinicians should consider the possibility of shorter remission periods.
Life‐history costs make perfect sprouting maladaptive in two herbaceous perennials
Authors: Shefferson Richard P. , Warren Robert J. , Pulliam H. Ronald 
Published: June 2014

Summary

Why some herbaceous plant species refrain from sprouting in some years is a longstanding puzzle in plant ecology. When vegetatively ‘dormant’, the plant lives as a rootstock, but does not produce or maintain photosynthetic tissue. During this time, energy may be remobilized from resource reserves or acquired from mycorrhizal fungi, although the mechanisms are still poorly understood. If vegetative dormancy is adaptive, it may be in response to a harsh environment, to life‐history costs, or as a bet‐hedge against unpredictable environmental variability.

We tested whether vegetative dormancy is adaptive via game theoretical analysis of deterministic and stochastic ahistorical and historical life‐history models parameterized with long‐term census data for two long‐lived plants, Anemone americana and Cypripedium parviflorum. The ahistorical deterministic model provided a test of the hypothesis that dormancy is adaptive in response to a generally harsh environment and/or short‐term life‐history costs, while the historical model tested whether long‐term costs drove the evolution of dormancy. The stochastic ahistorical model provided a test of whether dormancy is a bet‐hedging trait.

We found that vegetative dormancy is an adaptive consequence of life‐history costs of growth to survival and that these costs may be operating under a variable but generally harsh environment. Such costs led to sprouting and survival probabilities that generally increased with size in adults but never reached unity and decreased with size in juveniles. Historical deterministic models particularly predicted observed sprouting frequencies, while deterministic ahistorical and stochastic models did not, suggesting although the environment is likely stressful and fluctuates between harsh and mild states, short‐term costs and temporal stochasticity alone do not explain observed sprouting frequencies.

Synthesis. Life‐history costs can drive the evolution of seemingly paradoxical traits. In particular, growth can lead to survival costs that may become significant in future years. These costs may be incurred via the use of stored reserves that, once used, cannot be used in the next several years. Such costs are the currency favouring the evolutionary maintenance of vegetative dormancy in two distantly related perennial plant species and may account for dormancy throughout the plant kingdom.
A metagenetic approach for revealing community structure of marine planktonic copepods
Authors: Hirai J. , Kuriyama M. , Ichikawa T. , Hidaka K. , Tsuda A. 
Published: June 2014

AbstractMarine planktonic copepods are an ecologically important group with high species richness and abundance. Here, we propose a new metagenetic approach for revealing the community structure of marine planktonic copepods using 454 pyrosequencing of nuclear large subunit ribosomal DNA. We determined an appropriate similarity threshold for clustering pyrosequencing data into molecular operational taxonomic units (MOTUs) using an artificial community containing 33 morphologically identified species. The 99% similarity threshold had high species‐level resolution for MOTU clustering but overestimated species richness. The artificial community was appropriately clustered into MOTUs at 97% similarity, with little inflation in MOTU numbers and with relatively high species‐level resolution. The number of sequence reads of each MOTU was correlated with dry weight of that taxon, suggesting that sequence reads could be used as a proxy for biomass. Next, we applied the method to field‐collected samples, and the results corresponded reasonably well with morphological analysis of these communities. Numbers of MOTUs were well correlated with species richness at 97% similarity, and large numbers of sequence reads were generally observed in MOTUs derived from species with large biomass. Further, MOTUs were successfully classified into taxonomic groups at the family level at 97% similarity; similar patterns of species richness and biomass were revealed within families with metagenetic and morphological analyses. At the 99% similarity threshold, MOTUs with high proportions of sequence reads were identified as biomass‐dominant species in each field‐collected sample. The metagenetic approach reported here can be an effective tool for rapid and comprehensive assessment of copepod community structure.
Double hit lymphoma: the MD Anderson Cancer Center clinical experience
Authors: Oki Yasuhiro , Noorani Mansoor , Lin Pei , Davis Richard E. , Neelapu Sattva S. , Ma Long , Ahmed Mohamed , Rodriguez Maria Alma , Hagemeister Fredrick B. , Fowler Nathan , Wang Michael , Fanale Michelle A. , Nastoupil Loretta , Samaniego Felipe , Lee Hun J. , Dabaja Bouthaina S. , Pinnix Chelsea C. , Medeiros Leonard J. , Nieto Yago , Khouri Issa , Kwak Larry W. , Turturro Francesco , Romaguera Jorge E. , Fayad Luis E. , Westin Jason R. 
Published: June 2014

SummaryWe report our experience with 129 cases of double hit lymphoma (DHL), defined as B‐cell lymphoma with translocations and/or extra signals involving MYC plus BCL2 and/or BCL6. All cases were reviewed for histopathological classification. Median age was 62 years (range, 18–85), 84% of patients had advanced‐stage disease, and 87% had an International Prognostic Index score ≥2. Fourteen patients (11%) had a history of low‐grade follicular lymphoma. MYC translocation was present in 81%, and extra signals of MYC in 25% of patients. IGH‐BCL2 translocation was present in 84% and extra signals of BCL2 in 12% of patients. Two‐year event‐free survival (EFS) rates in all patients and patients who received R‐CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, prednisone), R‐EPOCH (rituximab, etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin), and R‐HyperCVAD/MA (rituximab, hyperfractionated cyclophosphamide, vincristine, doxorubicin, dexamethasone, alternating with cytarabine plus methotrexate) were 33%, 25%, 67% and 32%, respectively. In patients achieving complete response with initial therapy (n = 71), 2‐year EFS rates in patients who did (n = 23) or did not (n = 48) receive frontline stem cell transplantation were 68% and 53%, respectively (P = 0·155). The cumulative incidence of central nervous system involvement was 13% at 3 years. Multivariate analysis identified performance status ≥2 and bone marrow involvement as independent adverse prognostic factors for EFS and OS. Further research is needed to identify predictive and/or targetable biological markers and novel therapeutic approaches for DHL patients.
Functional relevance of NLRP3 inflammasome-mediated interleukin (IL)-1β during acute allergic airway inflammation
Authors: Ritter M , Straubinger K , Schmidt S , Busch D H , Hagner S , Garn H , Prazeres da Costa C , Layland L E 
Published: June 2014

Summary
Overall asthmatic symptoms can be controlled with diverse therapeutic agents. However, certain symptomatic individuals remain at risk for serious morbidity and mortality, which prompts the identification of novel therapeutic targets and treatment strategies. Thus, using an adjuvant-free T helper type 2 (Th2) murine model, we have deciphered the role of interleukin (IL)-1 signalling during allergic airway inflammation (AAI). Because functional IL-1β depends on inflammasome activation we first studied asthmatic manifestations in specific inflammasome-deficient [NACHT, LRR and PYD domains-containing protein 3 (NLRP3−/−) and apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC−/−)] and IL-1 receptor type 1−/− (IL-1R1−/−) mice on the BALB/c background. To verify the onset of disease we assessed cellular infiltration in the bronchial regions, lung pathology, airway hyperresponsiveness and ovalbumin (OVA)-specific immune responses. In the absence of NLRP3 inflammasome-mediated IL-1β release all symptoms of AAI were reduced, except OVA-specific immunoglobulin levels. To address whether manipulating IL-1 signalling reduced asthmatic development, we administered the IL-1R antagonist anakinra (Kineret®) during critical immunological time-points: sensitization or challenge. Amelioration of asthmatic symptoms was only observed when anakinra was administered during OVA challenge. Our findings indicate that blocking IL-1 signalling could be a potential complementary therapy for allergic airway inflammation.
Mechanical and hydrodynamic homecare devices to clean rough implant surfaces – an in vitro polyspecies biofilm study
Authors: Ioannidis Alexis , Thurnheer Thomas , Hofer Deborah , Sahrmann Philipp , Guggenheim Bernhard , Schmidlin Patrick R. 
Published: June 2014

AbstractObjectivesTo investigate the cleaning efficacy of a mechanical and a hydrodynamic homecare device on biofilm‐coated titanium surfaces with and without chlorhexidine.Material and methodsSix‐species biofilms were grown on 108 SLA‐titanium discs, which were cleaned as follows: sonic toothbrush alone (i) or in combination with either a 0.2% chlorhexidine (ii) or a placebo gel (iii) and oral irrigator (hydrodynamic action) with water (iv) or combined with 0.2% chlorhexidine solution (v). Untreated samples served as control (vi). Biofilms were then harvested either immediately after treatment (study part A) or after a regrowth phase of 24 h (study part B) and colony‐forming units (CFU) were assessed. Results were analysed using Whitney U‐tests between the treatment groups. After the Bonferroni correction, the significance level was set at α = 0.0033.ResultsThe median CFU counts directly after instrumentation accounted – in ascending order (P‐values in comparison with the control group A6 were <0.001 for all groups except for A3: P = 0.014) – 2.0E1 (A5), 1.1E5 (A4), 3.6E5 (A2), 3.3E5 (A1) and 6.8E6 (A3), respectively. The untreated control group showed the highest CFU counts: 1.8E7 (A6). After regrowth, the following CFU counts were measured in ascending order (all P‐values <0.001 when compared to the control group B6 = 2.0E8): 1.6E2 (B5), 1.9E5 (B2), 1.4E7 (B4), 3.1E7 (B1) and 3.9E7 (B3).ConclusionsAn oral irrigator combined with 0.2% chlorhexidine is effective in reducing biofilms attached to rough titanium surfaces immediately after cleaning. Following a regrowth phase of 24 h, micro‐organisms could be equally effective removed with a sonic toothbrush combined with 0.2% chlorhexidine and an oral irrigator with 0.2% chlorhexidine.
The influence of laparoscopy on incisional hernia rates: a retrospective analysis of 1057 colorectal cancer resections
Authors: Mishra A. , Keeler B. D. , Maxwell‐Armstrong C. , Simpson J. A. , Acheson A. G. 
Published: June 2014

AbstractAimThe aim of this study was to evaluate the incidence of incisional hernia formation after laparoscopic and open surgery for colorectal cancer.MethodA retrospective analysis was conducted of 1057 colorectal cancer resection cases (289 laparoscopic, 768 open) performed in a single national laparoscopic training centre between January 2006 and December 2011. Clinical notes and serial computed tomography scans were reviewed, with any incisional hernia including those at a surgical incision, port site, stoma and stoma closure site identified and the size of the defect measured.ResultsThe overall incisional hernia rate was 14.8%. There was no significant difference between the open and laparoscopic groups (14.4% vs 15.9%, P = 0.566). Excluding stoma‐related hernia, 10.7% of the open group developed a surgical wound hernia, and 11.1% of the laparoscopic group developed a hernia at a port site, extraction site or surgical midline incision. There was no statistical difference between the two groups (P = 0.853). The defects were smaller in the laparoscopic group (P < 0.005). There were significantly more parastomal hernias in the laparoscopic group (40%) than in the open group (12.7%, P < 0.001).ConclusionThe incidence of incisional hernia formation was similar after laparoscopic or open surgery for colorectal cancer. Parastomal hernia was more frequent after laparoscopic surgery.
To excise or not: impact of MelaFind on German dermatologists’ decisions to biopsy atypical lesions
Authors: Hauschild Axel , Chen Suephy C. , Weichenthal Michael , Blum Andreas , King Hadley C. , Goldsmith Jeff , Scharfstein Daniel , Gutkowicz‐Krusin Dina 
Published: June 2014

SummaryObjectivesTo determine the biopsy sensitivity to melanoma of dermatologists in Germany and the impact of MelaFind® on their decisions to biopsy melanomas.DesignRandomized two‐armed online reader study presenting case information, clinical/dermatoscopic images of pigmented skin lesions and MelaFind results (Arm 2).MethodsEach participant was asked to review 130 pigmented skin lesions. Biopsy decisions of dermatologists without MelaFind versus MelaFind and dermatologists without MelaFind versus dermatologists with MelaFind were compared.ResultsDermatologists without MelaFind had average sensitivity to melanoma of 69.5 % and average specificity of 55.9 %. MelaFind had greater sensitivity than dermatologists alone (96.9 % vs. 69.5 %, one‐sided p < 0.00001) and lower specificity (9.2 % vs. 55.9 %, one‐sided p < 0.00001). Dermatologists with MelaFind had higher sensitivity than those without MelaFind (78 % vs. 69.5 %, one‐sided p < 0.00001) and a lower specificity (45.8 % vs. 55.9 %, one‐sided p < 0.00001). The number of dermatologists detecting over 90 % of melanomas increased from 3 of 101 without MelaFind to 22 of 101 with MelaFind (p = 0.00006) while specificity remained relatively equivalent (23 % vs. 21 %, p = 0.99).ConclusionsThe MelaFind information, when incorporated into the final biopsy decision, can improve biopsy sensitivity with modest effect on biopsy specificity.
Parent support is less effective in buffering cortisol stress reactivity for adolescents compared to children
Authors: Hostinar Camelia E. , Johnson Anna E. , Gunnar Megan R. 
Published: June 2014

AbstractThe goal of the present study was to investigate developmental differences in the effectiveness of parent support to alleviate hypothalamic‐pituitary‐adrenal (HPA) axis stress responses of children (ages 9–10, N = 40) and adolescents (ages 15–16, N = 41). We experimentally manipulated the provision of parent support during the speech preparation period before a modified Trier Social Stress Test (TSST) and examined its effect on levels of salivary cortisol secreted in response to this laboratory stressor. Analyses revealed a significant interaction of condition and age group such that social support from the parent (versus a stranger) significantly eliminated the cortisol stress response in children, but had no effect on the response among adolescents.
Knowledge cannot explain the developmental growth of working memory capacity
Authors: Cowan Nelson , Ricker Timothy J. , Clark Katherine M. , Hinrichs Garrett A. , Glass Bret A. 
Published: June 2014

AbstractAccording to some views of cognitive growth, the development of working memory capacity can account for increases in the complexity of cognition. It has been difficult to ascertain, though, that there actually is developmental growth in capacity that cannot be attributed to other developing factors. Here we assess the role of item familiarity. We document developmental increases in working memory for visual arrays of English letters versus unfamiliar characters. Although letter knowledge played a special role in development between the ages of 6 and 8 years, children with adequate letter knowledge showed practically the same developmental growth in normalized functions for letters and unfamiliar characters. The results contribute to a growing body of evidence that the developmental improvement in working memory does not wholly stem from supporting processes such as encoding, mnemonic strategies, and knowledge. A video abstract is available at: https://www.youtube.com/watch?v=LJdqErLR2Hs&feature=youtu.be
Ranking factors affecting emissions of GHG from incubated agricultural soils
Authors: García‐Marco S. , Ravella S. R. , Chadwick D. , Vallejo A. , Gregory A. S. , Cárdenas L. M. 
Published: June 2014

SummaryAgriculture significantly contributes to global greenhouse gas (GHG) emissions and there is a need to develop effective mitigation strategies. The efficacy of methods to reduce GHG fluxes from agricultural soils can be affected by a range of interacting management and environmental factors. Uniquely, we used the Taguchi experimental design methodology to rank the relative importance of six factors known to affect the emission of GHG from soil: nitrate (NO3−) addition, carbon quality (labile and non‐labile C), soil temperature, water‐filled pore space (WFPS) and extent of soil compaction. Grassland soil was incubated in jars where selected factors, considered at two or three amounts within the experimental range, were combined in an orthogonal array to determine the importance and interactions between factors with a L16 design, comprising 16 experimental units. Within this L16 design, 216 combinations of the full factorial experimental design were represented. Headspace nitrous oxide (N2O), methane (CH4) and carbon dioxide (CO2) concentrations were measured and used to calculate fluxes. Results found for the relative influence of factors (WFPS and NO3− addition were the main factors affecting N2O fluxes, whilst glucose, NO3− and soil temperature were the main factors affecting CO2 and CH4 fluxes) were consistent with those already well documented. Interactions between factors were also studied and results showed that factors with little individual influence became more influential in combination. The proposed methodology offers new possibilities for GHG researchers to study interactions between influential factors and address the optimized sets of conditions to reduce GHG emissions in agro‐ecosystems, while reducing the number of experimental units required compared with conventional experimental procedures that adjust one variable at a time.