bluuebunny/crossref_metadata_2025_split huggingface dataset:
An analysis of the influence of microclimate on partial discharge activity in emissions of electric machines in the conditions of industrial operation – own research
Authors: Plutecki Zbigniew , Szymaniec Sławomir 
Published: December 2013

Abstract
The article presents the results of diagnostic measurements of partial discharge signal propagation from the winding insulation in electrical machinery, which were performed using an on-line method. This paper describes the results of experiments and the acquired experience in the monitoring of winding insulation in high power and high voltage electrical machines which are important in industrial production processes. The authors show the measurement techniques employed in their research. Representative measurement results are presented along with their analysis. The authors use an SKF monitoring systems to measure: vibrations, temperature, and humidity, as major factors affecting partial discharge activity in the from winding insulation of electrical machines.
A new Contribution on the Vascular Flora of Romania
Authors: Sîrbu Culiţă , Oprea Adrian 
Published: December 2013

Abstract
As a result of our field floristic studies in the recent years (2012 and 2013), we recorded some new data on the occurrence and chorology of three vascular plant species in Romania. Two of these are alien plants, invasive in many geographic regions of the world, namely: Acroptilon repens (an Asian species, reported as a newcomer in the flora of Romania, in this paper), and Picris echioides (a Mediterranean species, which is reported now in new localities). The third species, Pedicularis sylvatica, is a quite rare indigenous plant, critically threatened in Romania, reported here for the first time in the flora of Moldavia (eastern Romania).
Ascomycota Macrofungi New to Romania
Authors: Radu Mihai-Iulian 
Published: December 2013

Abstract
The paper gives a new contribution to the knowledge of Ascomycota macrofungi from Romania. The paper presents three Ascomycota species, Peziza phyllogena Cooke, Scutellinia superba (Velen.) Le Gal and Peroneutypa scoparia (Schwein.) Carmaran & A.I. Romero, reported for the first time in Romania. The species were uncovered and identified during a larger research regarding the diversity and distribution of macrofungi in the areas near Bucharest, Romania. Macro- and micro morphological descriptions, comments and illustrations of the species are presented.
On determination of ETL – a distributional approach
Authors: Pal Satyabrata , Ghosh Arunava , Dhar Tapamay 
Published: December 2013

Summary Economic threshold level (ETL) is an important component in pest management and control. Usually, it is determined by the grower/technologist utilizing his experience on a crop; however, for cereals the values of these indices are available. Knowledge of ETL helps reduce crop loss (and ensure less pesticide application), and as a consequence, profit is increased. Also substantial knowledge is required on the dynamics of the pest population, in order to determine the density at which the economic injury level (EIL) may be prevented (Weersink et al. 1991). This paper is devoted to the development of an analytical method (probabilistic) for determination of ETL, which is defined as the density at which control measures should be determined to prevent an increasing pest population from reaching the economic injury level. A method to model the dynamics of the pest population is also proposed. The above method is demonstrated on a real life data set on pest (whitefly) incidence on betelvine, obtained from an experiment designed for that purpose.
Use of Phasors in Nonlinear Analysis
Authors: Borys Andrzej , Zakrzewski Zbigniew 
Published: December 2013

Abstract
In this paper, the well-known method of phasor analysis of linear ac circuits is extended in a rigorous mathematical way to nonlinear analysis. This fills the lack of such a theory in the literature. The results derived enable carrying out the needed corrections of some results published recently that regard harmonic distortion analysis of weakly nonlinear circuits.
Two-Way Relaying Cooperative Wireless Networks: Resource Allocation and Performance Analysis
Authors: Abrar Muhammad , Gui Xiang , Punchihewa Amal 
Published: December 2013

Abstract
Relay-based cooperative wireless networks have been widely considered one of the cost-effective solutions to meet the demands in future wireless networks. In order to maximize the overall sum-rate while maintaining proportional fairness among users, we investigate different resource allocation algorithms in two-way relay networks with analog network coding (ANC) protocol and time division broadcast (TDBC) protocol. The algorithms investigated are different from traditional proportional fairness schemes in terms of fairness and computational complexity as we have applied Access Proportional Fairness (APF) and Minimum Rate Proportional Fairness (MRPF) along with load balancing at the relays. A MATLAB simulation has been performed and simulation results show the effectiveness of these algorithms.
Enhancement of Surgical Training Practice with the Spring Tensor Heuristic Model
Authors: Chiu Christopher , Chaczko Zenon 
Published: December 2013

Abstract
The enhancement of surgical simulation tools is an important research study, to assist in the assessment and feedback of medical training practice. In this research, the Spring Tensor Model (STEM) has been used for laparoscopic end-effector navigation through obstacles and high-risk areas. The modelling of the surgical trainer as part of the laparoscopic simulator seeks to emulate the physical environment as a virtualised representation in the integrated infrastructure. Combining sensor network framework paradigms to a surgical knowledge-based construct demonstrates how STEMcan enhance medical practice. The architectural hybridisation of the training framework has enabled the adaptation of STEM modelling techniques for a simulated laparoscopic training methodology. The primary benefit of the architecture is that this integration strategy has resulted in a seamless transition of the heuristic framework to be applied to surgical training.
Geochemistry of volcanogenic clayey marine sediments from the Hazar-Maden Basin (Eastern Turkey)
Authors: Akkoca Dicle Bal , Kürüm Sevcan , Huff Warren D. 
Published: December 2013

Abstract
The Hazar-Madeıı Basin sediments were deposited along the southern branch of the Neotethys Ocean margin during Late Maastrichtian-Middle Eocene times. X-ray powder diffraction (XRD), ICP-AES, ICP-MS and scanning electron microscopy (SEM) were performed on samples of the Upper Maastrichtian-Middle Eocene Hazar Group and the Middle Eocene Maden Complex from the Hazar-Maden Basin to investigate the main effects of depositional envi- ronmental parameters in three sections belonging to deeper marine (slope), proximal arc volcanic (Mastarhill and Yukaribag sections) and shallow platform marine (Sebken section) settings. Marine sediments contain clay minerals (smectite, smectite/chlorite, chlorite, illite, interstratified illite/smectite, illite/chlorite, palygorskite), clinoptilolite, quartz, feldspar, calcite, dolomite, opal-CT and hematite. The clays are dominated by iron-rich smectites. La, Zr and Th concentrations are high in the shallow marginal Sebken section where the terrestrial detrital contribution is significant, while Sc and Co are more dominant in the deeper marine (slope) Yukaribag section, which is represented by basic-type volcanism and a higher contribution of hydrothermal phases. In a chondrite-normalized REE diagram, the negative Eu anomaly in samples from Sebken, the section which was deposited in a shallow marine environment, is less significant than that of the other two sections indicating the presence of a high terrestrial contribution in that part of the basin. A decrease in LREE v/HREEiV and Lajv/Ybv, LaiV/Sin v ratios from Sebken to Mastarhill and the Yukaribag sections indi- cates deepening of the basin and an increasing contribution of volcanism in that direction.
Water repellency of soils with various content of organic matter in north-eastern Poland
Authors: Orzechowski Mirosław , Smólczyński Sławomir , Sowiński Paweł , Rybińska Beata 
Published: December 2013

Abstract
The objective of the work was to investigate hydrophobic properties of soil formations with various amounts of organic matter and occurring in young glacial landscape. The research was carried out in mineral, mineral-organic and organic (slightly and strongly silted mucks, sedge peat, alder wood peat, reed peat) soil formations. Water repellency is very important in soil protection. It favors the formation of stable aggregates and prevents from soil erosion. The study was carried out applying two methods . water drop penetration time test (WDPT) and alcohol percentage test (AP). Among 51 analyzed soil samples in WDPT test, 64.7% of mineral and mineral-organic soil formations were hydrophilic. Among organic soil formations 37.6% was slightly and strongly hydrophobic and they represented strongly silted mucks. Unsilted and slightly silted mucks, weakly and strongly decomposed peats, were very strongly (18.8%) and extremely (43.6%) hydrophobic. AP test showed that strongly silted mucks were moderately and very strongly hydrophobic. Slightly silted mucks, and peats were very strongly and extremely hydrophobic. It can be stated that water repellency decreases simultaneously with the degree of siltation of organic soil formations.
Validated TLC-densitometry method for determination of cetirizine dihydrochloride in tablet dosage form
Authors: Kristiningrum Nia , Martyanti Ellsy Novita 
Published: December 2013

A rapid, reproducible and accurate TLC method was developed for the determination of Cetirizine Dihydrochloride in tablet. The analytes were dissolved with ethanol 70% and chromatographed on silica Gel GF 254 TLC plate using chloroform : methanol : ethyl acetate in the ratio of 2 : 7 : 3 (v/v) as mobile phase. Quantitative analysis was done through densitometric measurement at wavelength 234 nm. Method was found linear over the concentration range of 400  1600 ng/spot with the correlation coefficient of 0.996. Specificity showed calculation of purity and identity more than 0.99. The limit of detection (LOD) and the limit of quantification (LOQ) of the method were 75.54 and 226.64 ng/spot. The relative standard deviation of this method was 0.86% whereas the means of the recovery data was 100.54 ± 0.11%. The proposed method has been applied to the determination of Cetirizine Dihydrochloride in commercial tablet formulations and the result were 96.97 ± 0.86 % for brand A and 100.57 ± 1.17 % for brand B. The developed method was successfully used for the assay of Cetirizine Dihydrochloride. This method is simple, sensitive and precise; it can be used for the routine quality control testing of marketed formulations.DOI: http://dx.doi.org/10.3329/icpj.v3i1.17294 International Current Pharmaceutical Journal, December 2013, 3(1): 208-210
Evaluation of cytotoxicity, anti-herpes simplex virus type 1 (HSV-1) and antibacterial activities of Ficus vasta and phytoconstituents
Authors: Rashed Khaled , Ono Lucy 
Published: December 2013

This study deals with the evaluation of in vitro cytotoxicity of the methanol 80% extract of Ficus vasta aerial parts in Vero cells, anti-HSV-1 and antibacterial activities and the determination of the phytochemical content of the F. vasta methanol extract. The extract was tested for its cytotoxicity in Vero cells and for anti-HSV-1 and against bacterial strains as S. aureus, S. epidermidis, E. coli and P. aeruginosa and also phytochemical constituents were detected. The results showed that this extract presented a CC50 value of 389 µg/mL, an intermediate value taking into account other researchers reported for some Moraceae species. Regarding the other biological activities, antiviral effect was not demonstrated by a HSV-1 challenge dilution of 100x tissue culture infective dose 50% (TCID50) and also by the disk-diffusion method at the higher non-toxic concentration of the extract (119 µg/mL). Phytochemical analysis of the methanol extract proved the presence of carbohydrates, tannins, flavonoids, coumarins, alkaloids and triterpenes. Chromatographic separation of the methanol extract resulted in the isolation and identification of ?-sitosterol, stigmasterol, lupeol, ursolic acid, naringenin, luteolin, quercetin, vitexin, quercetin 3-O-?-glucoside and rutin. The results indicated that F. vasta aerial parts methanol extract is potential candidate for experiments of biological activity screening that are not anti-HSV-1 or antibacterial against the strains evaluated in this study, to be carried on in the future.DOI: http://dx.doi.org/10.3329/icpj.v3i1.17295 International Current Pharmaceutical Journal, December 2013, 3(1): 211-218
Insulin Inhibits IL-10–Mediated Regulatory T Cell Function: Implications for Obesity
Authors: Han Jonathan M. , Patterson Scott J. , Speck Madeleine , Ehses Jan A. , Levings Megan K. 
Published: December 2013

Abstract
Chronic inflammation is known to promote metabolic dysregulation in obesity and type 2 diabetes. Although the precise origin of the unchecked inflammatory response in obesity is unclear, it is known that overproduction of proinflammatory cytokines by innate immune cells affects metabolism. For example, TNF-α contributes to the inability of cells to respond to insulin and to the increase in levels of insulin. Whether this hyperinsulinemia itself is part of a feedback loop that affects the progression of chronic adipose inflammation is unknown. In this article, we show that regulatory T cells (Tregs) express the insulin receptor, and that high levels of insulin impair the ability of Tregs to suppress inflammatory responses via effects on the AKT/mTOR signaling pathway. Insulin activated AKT signaling in Tregs, leading to inhibition of both IL-10 production and the ability of Tregs to suppress the production of TNF-α by macrophages in a contact-independent manner. The effect of insulin on Treg suppression was limited to IL-10 production and it did not alter the expression of other proteins associated with Treg function, including CTLA-4, CD39, and TGF-β. In a model of diet-induced obesity, Tregs from the visceral adipose tissue of hyperinsulinemic, obese mice showed a similar specific decrease in IL-10 production, as well as a parallel increase in production of IFN-γ. These data suggest that hyperinsulinemia may contribute to the development of obesity-associated inflammation via a previously unknown effect of insulin on the IL-10–mediated function of Tregs.
Small Molecule-Mediated Directed Differentiation of Human Embryonic Stem Cells Toward Ventricular Cardiomyocytes
Authors: Karakikes Ioannis , Senyei Grant D. , Hansen Jens , Kong Chi-Wing , Azeloglu Evren U. , Stillitano Francesca , Lieu Deborah K. , Wang Jiaxian , Ren Lihuan , Hulot Jean-Sebastien , Iyengar Ravi , Li Ronald A. , Hajjar Roger J. 
Published: December 2013

Abstract

The generation of human ventricular cardiomyocytes from human embryonic stem cells and/or induced pluripotent stem cells could fulfill the demand for therapeutic applications and in vitro pharmacological research; however, the production of a homogeneous population of ventricular cardiomyocytes remains a major limitation. By combining small molecules and growth factors, we developed a fully chemically defined, directed differentiation system to generate ventricular-like cardiomyocytes (VCMs) from human embryonic stem cells and induced pluripotent stem cells with high efficiency and reproducibility. Molecular characterization revealed that the differentiation recapitulated the developmental steps of cardiovascular fate specification. Electrophysiological analyses further illustrated the generation of a highly enriched population of VCMs. These chemically induced VCMs exhibited the expected cardiac electrophysiological and calcium handling properties as well as the appropriate chronotropic responses to cardioactive compounds. In addition, using an integrated computational and experimental systems biology approach, we demonstrated that the modulation of the canonical Wnt pathway by the small molecule IWR-1 plays a key role in cardiomyocyte subtype specification. In summary, we developed a reproducible and efficient experimental platform that facilitates a chemical genetics-based interrogation of signaling pathways during cardiogenesis that bypasses the limitations of genetic approaches and provides a valuable source of ventricular cardiomyocytes for pharmacological screenings as well as cell replacement therapies.
Effets de l’acculturation sur l’apprentissage des étudiants africains dans la Haute École Spécialisée de Suisse occidentale
Authors: Gakuba Théogène-Octave , Graber Myriam 
Published: December 2013

Cet article analyse les effets de l’acculturation sur l’apprentissage des étudiant(e)s d’Afrique subsaharienne suivant une formation professionnelle en santé et travail social en Suisse romande. Il concerne une recherche que nous avons menée pour comprendre les conditions d’apprentissage et d’intégration de ces étudiants. Notre approche se fonde sur les théories de la communication interculturelle, de l’interculturalisation et de l’apprentissage des adultes avec une démarche méthodologique qualitative : entretiens compréhensifs et semi-directifs ainsi que l’étude de dossiers administratifs d’étudiants. Des pistes de réflexion pour une meilleure intégration des étudiants étrangers sont proposées.
Les programmes québécois d’histoire nationale (1982-2007) et l’apprentissage de la pensée historique : vers l’identification d’un problème de conceptualisation
Authors: Moreau Daniel 
Published: December 2013

Cet article porte sur l’analyse d’une interprétation des deux plus récents programmes d’histoire nationale publiés au Québec, leur attribuant l’apprentissage de la pensée : une lecture critique s’appuyant sur les six critères définis par Martineau (1997), premier chercheur à avoir formulé cette interprétation, permettra de révéler une divergence dans trois d’entre eux : 1) le caractère signifiant de l’apprentissage ; 2) la métacognition ; et 3) la fréquence de l’exercice. Cette divergence va justifier la pertinence, d’une part, d’une analyse plus approfondie de ces programmes, et, d’autre part, d’une révision de ces critères en fonction de nouveaux fondements théoriques.
Mice deficient in the phosphatase activity of sEH show decreased levels of the endocannabinoid 2‐AG in the olfactory bulb and depressive‐like behavior
Authors: Oguro Ami , Kaga Yurino , Sato Hideaki , Fujiyama Taichi , Fujimoto Shinji , Nagai Saki , Matsuyama Makoto , Miyara Masatsugu , Ishihara Yasuhiro , Yamazaki Takeshi , Imaoka Susumu , Kotake Yaichiro 
Published: July 2024

Soluble epoxide hydrolase (sEH) is a bifunctional enzyme that has epoxide hydrolase activity and phosphatase activity. Our earlier study revealed that lysophosphatidic acids are a substrate of the phosphatase activity of sEH in vitro, but its physiological function remained unknown. Herein, we used the CRISPR/Cas9 system and i‐GONAD method to generate mice that are deficient in sEH phosphatase activity. In the mouse brain, sEH was highly expressed in the olfactory bulb. Deletion of the sEH phosphatase activity resulted in decreased levels of the endocannabinoid 2‐arachidonoyl glycerol (2‐AG), which is a dephosphorylated form of 2‐arachidonoyl‐lysophosphatidic acid in the olfactory bulb. The sEH‐deficient mice showed depressive‐like behavior. These results indicate that sEH can regulate the production of 2‐AG and brain function in vivo.
Liquid Metal Alloys Enable Efficient Formate Electrosynthesis
Authors: Huang Haoling , Ding Xue , Mao Xinnan , Yan Yuchen , Lv Fang , Pan Binbin , Huang Wei , Wang Lu , Han Na , Li Yanguang 
Published: July 2024

AbstractLiquid metals are an interesting class of materials with the unique combination of metallic nature and liquid fluidity, and have recently been explored in many emerging fields. Their potential applications in catalysis, unfortunately, remain largely untapped. Herein, Ga‐mediated liquid metal alloying as an effective strategy is demonstrated to prepare functional alloys for catalysis. The alloying is carried out by dissolving indium or tin pellets in liquid gallium at room temperature or assisted by gentle heating, giving rise to binary Ga1−xInx and Ga1−xSnx liquid metal alloys with tunable chemical compositions. When further subjected to ultrasonication in water, they are ruptured into nanosized particles with liquid metal cores and thin surface oxide shells. Electrochemical measurements reveal that the liquid metal alloying significantly promotes electrocatalytic CO2 reduction to formate. Taking Ga0.75In0.25 as an example, its formate Faradaic efficiency is enhanced by 10%–20% compared to those of Ga and In, and its formate partial current density is 4–6 times larger than those of Ga and In. This enhancement is rationalized via computational simulations showing that the surrounding of In active sites with Ga atoms deactivates the undesirable reaction pathways to CO or H2, and facilitates selective formate electrosynthesis.
FeAu Bimetallic Nanoparticle as Fe(0) Reservoir for Near Infrared Laser Enhanced Ferroptosis/Pyroptosis‐Based Tumor Immunotherapy
Authors: Ruan Yiling , Wu Xiaojing , Li Keying , Shen Jingjing , Gong Jinglang , Feng Kai , Sun Shouheng , Sun Xiaolian 
Published: July 2024

AbstractIron (Fe)‐based nanoparticles (NPs) have attracted considerable attention in nanomedicine research due to their enhancement effects in magnetic resonance imaging (MRI) and cancer therapy. Although zero‐valent Fe (Fe(0)) can serve as an active catalyst to decompose H2O2 into reactive oxygen species (ROS), its activity is compromised in physiological conditions due to its susceptibility to oxidation. Here it is reported that a 9 nm FeAu alloy NP system can efficiently stabilize Fe(0) in neutral pH solution, but release Fe(0) in tumor‐bearing environment, catalyzing H2O2 decomposition to ROS. Although Fe3O4 NPs and Au NPs are well‐known for their biocompatible, FeAu NPs effectively eliminate cancer cells at an IC50 as low as 15 µg mL−1 Fe. Further proteomics analysis reveals that FeAu NPs can concomitantly induce both ferroptosis and pyroptosis. Additional near‐infrared (NIR) irradiation further increases cell death and promotes maturation of dendritic cells within tumor‐draining lymph nodes and infiltration of helper T cells and cytotoxic T lymphocytes within tumor sites, resulting in significant reduction in tumor growth and metastasis. The studies demonstrate a great potential of FeAu NPs as a stable Fe(0) reservoir for pH/NIR controlled Fe(0) release and further for ferroptosis and pyroptosis co‐mediated tumor immunotherapy.