bluuebunny/crossref_metadata_2025_split huggingface dataset:
A hybrid yang transform adomian decomposition method for solving time-fractional nonlinear partial differential equation
Authors: Bekela Alemu Senbeta , Deresse Alemayehu Tamirie 
Published: August 2024

AbstractNonlinear time-fractional partial differential equations (NTFPDEs) play a great role in the mathematical modeling of real-world phenomena like traffic models, the design of earthquakes, fractional stochastic systems, diffusion processes, and control processing. Solving such problems is reasonably challenging, and the nonlinear part and fractional operator make them more problematic. Thus, developing suitable numerical methods is an active area of research. In this paper, we develop a new numerical method called Yang transform Adomian decomposition method (YTADM) by mixing the Yang transform and the Adomian decomposition method for solving NTFPDEs. The derivative of the problem is considered in sense of Caputo fractional order. The stability and convergence of the developed method are discussed in the Banach space sense. The effectiveness, validity, and practicability of the method are demonstrated by solving four examples of NTFPEs. The findings suggest that the proposed method gives a better solution than other compared numerical methods. Additionally, the proposed scheme achieves an accurate solution with a few numbers of iteration, and thus the method is suitable for handling a wide class of NTFPDEs arising in the application of nonlinear phenomena.
Epidemiological features and temporal trends of the co-infection between HIV and tuberculosis, 1990–2021: findings from the Global Burden of Disease Study 2021
Authors: Zhang Shun-Xian , Wang Ji-Chun , Yang Jian , Lv Shan , Duan Lei , Lu Yan , Tian Li-Guang , Chen Mu-Xin , Liu Qin , Wei Fan-Na , Feng Xin-Yu , Yang Guo-Bing , Li Yong-Jun , Wang Yu , Hu Xiao-Jie , Yang Ming , Lu Zhen-Hui , Zhang Shao-Yan , Li Shi-Zhu , Zheng Jin-Xin 
Published: August 2024

Abstract
Background
The co-infection of human immunodeficiency virus (HIV)/acquired immune deficiency syndrome (AIDS) and tuberculosis (TB) poses a significant clinical challenge and is a major global public health issue. This study aims to elucidate the disease burden of HIV-TB co-infection in global, regions and countries, providing critical information for policy decisions to curb the HIV-TB epidemic.

Methods
The ecological time-series study used data from the Global Burden of Disease (GBD) Study 2021. The data encompass the numbers of incidence, prevalence, mortality, and disability-adjusted life year (DALY), as well as age-standardized incidence rate (ASIR), prevalence rate (ASPR), mortality rate (ASMR), and DALY rate for HIV-infected drug-susceptible tuberculosis (HIV-DS-TB), HIV-infected multidrug-resistant tuberculosis (HIV-MDR-TB), and HIV-infected extensively drug-resistant tuberculosis (HIV-XDR-TB) from 1990 to 2021. from 1990 to 2021. The estimated annual percentage change (EAPC) of rates, with 95% confidence intervals (CIs), was calculated.

Results
In 2021, the global ASIR for HIV-DS-TB was 11.59 per 100,000 population (95% UI: 0.37–13.05 per 100,000 population), 0.55 per 100,000 population (95% UI: 0.38–0.81 per 100,000 population), for HIV-MDR-TB, and 0.02 per 100,000 population (95% UI: 0.01–0.03 per 100,000 population) for HIV-XDR-TB. The EAPC for the ASIR of HIV-MDR-TB and HIV-XDR-TB from 1990 to 2021 were 4.71 (95% CI: 1.92–7.59) and 13.63 (95% CI: 9.44–18.01), respectively. The global ASMR for HIV-DS-TB was 2.22 per 100,000 population (95% UI: 1.73–2.74 per 100,000 population), 0.21 per 100,000 population (95% UI: 0.09–0.39 per 100,000 population) for HIV-MDR-TB, and 0.01 per 100,000 population (95% UI: 0.00–0.03 per 100,000 population) for HIV-XDR-TB in 2021. The EAPC for the ASMR of HIV-MDR-TB and HIV-XDR-TB from 1990 to 2021 were 4.78 (95% CI: 1.32–8.32) and 10.00 (95% CI: 6.09–14.05), respectively.

Conclusions
The findings indicate that enhancing diagnostic and treatment strategies, strengthening healthcare infrastructure, increasing access to quality medical care, and improving public health education are essential to combat HIV-TB co-infection.

Graphical Abstract
Diffusion of fashion trend information: a study on fashion image mining from various sources
Authors: Choi Woojin , Lee Yuri , Jang Seyoon 
Published: August 2024

AbstractThe advancement in the internet and mobile technologies has substantially altered information diffusion in modern society, creating a diverse environment for generating and sharing various forms of information. Specifically, the emergence of new information sources, such as influencers and online communities, has significantly influenced the formation of consumer opinion. We highlight the changes that have occurred in the diffusion of fashion trend information. To do this, we conducted data mining, which involved three main steps: data preprocessing, specifically converting image data (including images from the 2022 F/W season runway collection, fashion influencer outfits, and best items from online fashion retailers) into textual data; data mining analysis (quantitative analysis); and data post-processing. As a result, we found that even items with low or no appearance on the runway held significance in the best item data or fashion influencer outfits. Specifically, the best items on online fashion retailers, reflecting popular fashion trends, had greater similarity to fashion influencer outfits. However, similarities in silhouette attributes were found among runway collections, fashion influencer outfits, and best items data. This study holds great significance because it focuses on fashion items genuinely consumed by the mainstream consumers rather than only focusing on the four major runway collections. Furthermore, these findings offer valuable insights for merchandising and trend forecasting, emphasizing the importance of selectively utilizing fashion trend information in the planning of fashion products.
Spontaneous mesenteric hematoma occurring during antithrombotic therapy and responsive to surgical treatment: a case report
Authors: Aoki Meiko , Yoshii Hisamichi , Fujino Rika , Izumi Hideki , Mukai Masaya , Makuuchi Hiroyasu 
Published: August 2024

Abstract
Background
Spontaneous mesenteric hematoma is a rare condition that is diagnosed when clinical and pathological findings do not identify an obvious causative disease. Various treatment options for spontaneous mesenteric hematoma exist; however, there are no clear treatment criteria. Herein, we report a case of spontaneous mesenteric hematoma that was successfully treated surgically and discuss the optimum treatment strategy based on similar cases.

Case presentation
A 63-year-old man with abdominal persisting for 3 days presented to our hospital after going into shock without any triggers. The patient had a history of atrial fibrillation, stroke, and an aneurysm, and was receiving antithrombotic therapy. Abdominal contrast-enhanced computed tomography revealed a mass structure within the sigmoid mesentery, which was suspected to be a hematoma. The patient was admitted to the hospital for follow-up observation after initial infusion and vital stabilization. However, the following day, the patient developed acute generalized peritonitis with necrosis of the sigmoid colon; therefore, emergency Hartmann’s surgery was performed. Intraoperative and histopathological examinations revealed no evidence of bleeding.

Conclusion
Spontaneous mesenteric hematomas tend to be associated with intestinal necrosis and may require surgical treatment with bowel resection owing to the difficulty in identifying the responsible vessel. Moreover, our results suggest that the presence of antithrombotic therapy may be an important factor affecting spontaneous mesenteric hematoma development.
Percutaneous pericardiocentesis using the apical approach: case series and review of the literature
Authors: Alaiwah Malek , Hassanin Ahmed , Abbasi Danish , Rayes Hamza , Hassan Zahra , Albadaineh Mu’nes , Mansour Munthir , Devabhaktuni Subodh , Tarun Tushar , Vallurupalli Srikanth , Mounsey John P. , Al’Aref Subhi J. 
Published: August 2024

Abstract
Background
Pericardiocentesis offers a definitive diagnostic and a life-saving therapeutic modality through removal of pericardial fluid and relief of high intrapericardial pressure. Percutaneous pericardiocentesis has been performed via different approaches depending on different institutional experiences. In this paper, we present our institutional experience and review the current literature of the different approaches for performing percutaneous pericardiocentesis.

Materials and methods
We evaluated consecutive patients who underwent echocardiographic-guided pericardiocentesis via the apical approach for pericardial effusion between the period of April 1st, 2022, and April 1st, 2023, at University of Arkansas for Medical Sciences (UAMS). Health records were reviewed for clinical presentations, available imaging findings, procedural outcomes, and short-term follow up.

Results
A total of eight consecutive cases of pericardiocentesis via the apical approach were found. Seven were successful. No complications were reported. Six patients had evidence of tamponade physiology on echocardiogram.

Conclusion
Historically, pericardiocentesis has been most performed via the subxiphoid approach. However, an ultrasound-guided apical approach offers a safe and effective alternative and may be preferable in patients with challenging anatomies.
Unveiling Meghalaya topography: slope length gradient (LS) factor estimation for insightful soil erosion evaluation
Authors: Badavath Naveen , Sahoo Smrutirekha , Samal Rasmiranjan 
Published: August 2024

AbstractMeghalaya is known for its complex environment due to its hilly terrain and heavy rains, which result in significant soil erosion challenges. The LS factor is the primary factor used to estimate soil loss. Acquiring accurate LS values has always been a significant challenge. The main aim of this research is to compute the LS factor in the Meghalaya region. Three methods are used to calculate the LS factor: (1) Wischmeier and Smith’s (1978) method, (2) Moore and Wilson’s (1992) method, and (3) Desmet and Gover’s (1996) method. All three approaches used the digital elevation model (DEM) in the spatial domain to determine the LS factor. The results of this investigation demonstrated significant variation in LS factor in all three methods. Wischmeier and Smith’s method yielded LS factor values ranging from 0 to 266.538, Moore and Wilson’s method resulted in values ranging from 0 to 112.631, and Desmet and Gover’s method resulted in values ranging from 0 to 683.679. This study concluded that Wischmeier and Smith’s method resulted in LS factor values distributed uniformly across the spatial domain. In contrast, Moore and Wilson’s method only yielded high values along the flow path and low values in other areas. Additionally, Desmet and Gover’s method identified high LS factors in regions with steep slopes near rivers and streamlines. This study can be helpful in anticipating soil erosion well before time and also in developing a slope management plan in the study region.
The use of angiotensin II for the management of distributive shock: expert consensus statements
Authors: Landoni Giovanni , Cortegiani Andrea , Bignami Elena , De Pascale Gennaro , Donadello Katia , Donati Abele , Grasselli Giacomo , Guarracino Fabio , Monti Gianpaola , Paternoster Gianluca , Tritapepe Luigi , Girardis Massimo 
Published: August 2024

Abstract
Background
Despite the growing body of evidence supporting the use of angiotensin II (ATII) in distributive shock, its integration into existing treatment algorithms requires careful consideration of factors related to patient comorbidities, hemodynamic parameters, cost-effectiveness, and risk–benefit balance. Moreover, several questions regarding its use in clinical practice warrant further investigations. To address these challenges, a group of Italian intensive care specialists (the panel) developed a consensus process using a modified Delphi technique.

Methods
The panel defined five clinical questions during an online scoping workshop and then provided a short list of statements related to each clinical question based on literature review and clinical experience. A total of 20 statements were collected. Two coordinators screened and selected the final list of statements to be included in the online survey, which consisted of 17 statements. The consensus was reached when ≥ 75% of respondents assigned a score within the 3-point range of 1–3 (disagreement) or 7–9 (agreement).

Results
Overall, a consensus on agreement was reached on 13 statements defining the existing gaps in scientific evidence, the possibility of evaluating the addition of drugs with different mechanisms of action for the treatment of refractory shock, the utility of ATII in reducing the catecholamine requirements in the treatment of vasopressor-resistant septic shock, and the effectiveness of ATII in treating patients in whom angiotensin-converting enzyme activity is reduced or pharmacologically blocked. It was widely shared that renin concentration can be used to identify patients who most likely benefit from ATII to restore vascular tone. Thus, the patients who might benefit most from using ATII were defined. Lastly, some potential barriers to the use of ATII were described.

Conclusions
ATII was recognized as a useful treatment to reduce catecholamine requirements in treating vasopressor-resistant septic shock. At the same time, the need for additional clinical trials to further elucidate the efficacy and safety of ATII, as well as investigations into potential mechanisms of action and optimization of treatment protocols in patients with refractory distributive shock, emerged.
Identifying clinically relevant agranulocytosis in people registered on the UK clozapine Central Non-Rechallenge Database: retrospective cohort study
Authors: Oloyede Ebenezer , Bachmann Christian J. , Dzahini Olubanke , Lopez Alcaraz Juan Miguel , Singh Shaurya Dev , Vallianatu Kalliopi , Funk Burkhardt , Whiskey Eromona , Taylor David 
Published: August 2024

BackgroundClozapine is the most effective antipsychotic for treatment-resistant psychosis. However, clozapine is underutilised in part because of potential agranulocytosis. Accumulating evidence indicates that below-threshold haematological readings in isolation are not diagnostic of life-threatening clozapine-induced agranulocytosis (CIA).AimsTo examine the prevalence and timing of CIA using different diagnostic criteria and to explore demographic differences of CIA in patients registered on the UK Central Non-Rechallenge Database (CNRD).MethodWe analysed data of all patients registered on the UK Clozaril® Patient Monitoring Service Central Non-Rechallenge Database (at least one absolute neutrophil count (ANC) < 1.5 × 109/L and/or white blood cell count < 3.0 × 109/L) between May 2000 and February 2021. We calculated prevalence rates of agranulocytosis using threshold-based and pattern-based criteria, stratified by demographic factors (gender, age and ethnicity). Differences in epidemiology based on rechallenge status and clozapine indication were explored. The proportion of patients who recorded agranulocytosis from a normal ANC was explored.ResultsOf the 3029 patients registered on the CNRD with 283 726 blood measurements, 593 (19.6%) were determined to have threshold-based agranulocytosis and 348 (11.4%) pattern-based agranulocytosis. In the total sample (75 533), the prevalence of threshold-based agranulocytosis and pattern-based agranulocytosis was 0.8% and 0.5%, respectively. The median time to threshold-based agranulocytosis was 32 weeks (IQR 184) and 15 (IQR 170) weeks for pattern-based agranulocytosis. Among age groups, the prevalence of pattern-based agranulocytosis and threshold-based agranulocytosis was highest in the >48 age group. Prevalence rates were greatest for White (18%) and male individuals (13%), and lowest for Black individuals (0.1%). The proportion of people who were determined to have pattern-based agranulocytosis without passing through neutropenia was 70%.ConclusionsThreshold-based definition of agranulocytosis may over-diagnose CIA. Monitoring schemes should take into consideration neutrophil patterns to correctly identify clinically relevant CIA. In marked contrast to previous studies, CIA occurred least in Black individuals and most in White individuals.
Identification and Validation of Prognostic Model for Tumor Microenvironment-Associated Genes in Bladder Cancer Based on Single-Cell RNA Sequencing Data Sets
Authors: Safder Imran , Valentine Henkel , Uzzo Nicole , Sfakianos John , Uzzo Robert , Gupta Shilpa , Brown Jason , Ranti Daniel , Plimack Elizabeth , Haber George , Weight Christopher , Kutikov Alexander , Abbosh Philip , Bukavina Laura 
Published: August 2024

PURPOSE The purpose of this study was to elucidate the relationship between the tumor microenvironment (TME) and cellular diversity in bladder cancer (BLCA) progression, leveraging single-cell RNA sequencing (scRNA-seq) data to identify potential prognostic biomarkers and construct a prognostic model for BLCA. METHODS We analyzed scRNA-seq data of normal and tumor bladder cells from the Gene Expression Omnibus (GEO) database to uncover crucial markers within the bladder TME. The study compared gene expression in normal versus tumor bladder cells, identifying differentially expressed genes. These genes were subsequently assessed for their prognostic significance using patient follow-up data from The Cancer Genome Atlas. Prognostic models were constructed using Least Absolute Shrinkage and Selection Operator and multivariate Cox regression analyses, focusing on eight genes of interest. The predictive performance of the model was also tested against additional GEO data sets (GSE31684, GSE13507, and GSE32894). RESULTS The prognostic model demonstrated reliable prediction of patient outcomes. Validation through gene set enrichment analysis and immune cell infiltration assessment supported the model's efficacy. The results from both the univariate and multivariate analyses suggest that the risk score is an independent prognostic factor with a hazard ratio of 2.97 (95% CI, 2.28 to 3.9, P < .001). In the validation cohort, the AUC at 1, 2, and 3 years is 0.74, 0.74, and 0.72, respectively. CONCLUSION Our findings proposed biomarkers with prognostic potential, laying the groundwork for future in vitro validation and therapeutic exploration. This contributes to a deeper understanding of the genes associated with bladder TME and may improve prognostic precision in BLCA management.
Extraventricular Neurocytoma of the Sellar Region Presenting With Syndrome of Inappropriate Antidiuresis
Authors: Lamback Elisa , Filho Ferdinand Duenas Cabrera , Ventura Nina , Chimelli Leila , Christ-Crain Mirjam , Gadelha Mônica R 
Published: August 2024

Abstract
Neurocytomas are neuronal tumors that are usually intraventricular. Rare cases can arise from extraventricular sites. To our knowledge, only 29 cases of extraventricular neurocytoma of the sellar region (EVNSR) have been reported in the literature. We describe a case of a 39-year-old woman who presented with a one-month history of refractory headache, nausea and vomiting. Magnetic resonance imaging (MRI) showed a 5.1 × 3.1 × 2.2 cm sellar and suprasellar mass, suggestive of a pituitary adenoma (PA). She had hyponatremia, obstructive hydrocephalus, and panhypopituitarism at presentation (hypogonadism, adrenal insufficiency). After glucocorticoid replacement therapy and ventriculoperitoneal shunt, the vomiting and headache resolved, but she remained with nausea and hyponatremia. She was submitted to surgery, and histopathological analysis revealed a neurocytoma with positive immunostaining for arginine vasopressin. Syndrome of inappropriate antidiuresis (SIAD) was diagnosed but did not resolve after surgery due to residual tumor, despite fluid restriction and saline replacement. SIAD later resolved with empagliflozin. In conclusion, EVNSR is extremely rare and can be misdiagnosed as PA on MRI. In the context of SIAD and extraventricular neurocytoma, a secreting arginine vasopressin tumor must be considered. SIAD can be challenging to treat, with excision of the EVNSR the treatment choice and, alternatively, empagliflozin associated with fluid restriction.
Thyroid Paraganglioma: A Rare Manifestation of Paraganglioma Syndrome Associated With Pathogenic Variant in SDHD
Authors: Tarasova Valentina D , Samuel Kelara , McMullen Caitlin , Kushchayev Sergiy , Hernandez Prera Juan C , Veloski Colleen 
Published: August 2024

Abstract
Evaluation of an incidentally discovered indeterminate thyroid nodule (TN) in a previously healthy 59-year female led to diagnosis of thyroid paraganglioma (TPGL) and subsequently hereditary succinate dehydrogenase complex subunit D (SDHD)-related multifocal head and neck paragangliomas (PGLs). An ultrasound-guided fine needle aspiration (FNA) biopsy of the 1.7-cm TN was nondiagnostic and core biopsy was suspicious for papillary thyroid carcinoma. Pathology slides reviewed at tertiary center showed neuroendocrine neoplasm consistent with PGL. Her 24-hour urinary catecholamines and metanephrines were normal. Given the diagnosis of TPGL, genetic testing was recommended, which identified a pathogenic variant in SDHD (c.242C &gt; T(p.P81L). Gallium-68-DOTATATE PET/CT revealed multifocal areas of increased somatostatin receptor expression from the skull base to thoracic inlet. Magnetic resonance imaging of the brain/neck showed multiple PGLs (right jugular, carotid, thyroid, left vagal, left level II, and superior mediastinal), all measured up to 1.7 cm. The right jugular PGL was treated with external beam radiation therapy of 3000 cGy. All PGLs remained stable and asymptomatic at 22-month follow-up imaging. TPGL should be considered in the differential diagnosis of a hypervascular TN in patients with SDHx-related pheochromocytoma-PGL syndromes and when such lesions with indeterminate cytology are encountered in patients with no known history of SDHx-mutation or syndrome.