bluuebunny/crossref_metadata_2025_split huggingface dataset:
Awake versus asleep deep brain stimulation for Parkinson’s disease: a comprehensive systematic review and meta-analysis
Authors: Maroufi Seyed Farzad , Fallahi Mohammad Sadegh , Hosseinzadeh Asli Saba , Khorasanizadeh MirHojjat , Pour-Rashidi Ahmad , Ponce Francisco A. , Slavin Konstantin V. 
Published: August 2024

OBJECTIVE
Deep brain stimulation (DBS) has become an effective and safe treatment in patients with Parkinson’s disease (PD) not responding to conventional treatments. With the growing body of literature regarding the use of DBS in different movement disorders, there remain controversies regarding performing awake or asleep DBS. This systematic review provides the most comprehensive review of the literature comparing the two techniques from various aspects in detail.

METHODS
A systematic review of the PubMed, Scopus, Web of Science, and Cochrane Library databases was conducted. All studies comparing any aspects of asleep and awake DBS were included. Risk of bias was assessed using the Risk of Bias in Non-Randomized Studies of Interventions tool. Meta-analysis was conducted with consideration of baseline characteristics.

RESULTS
Thirty-one studies with 2563 PD patients were included. A total of 1423 patients underwent asleep DBS. The two groups were comparable regarding their baseline characteristics. The follow-up ranged from 3 to 60 months. The two DBS techniques were comparable in terms of motor symptom improvements and levodopa equivalent daily doses. However, the asleep technique showed slightly better improvements in Mattis Dementia Rating Scale and Parkinson’s Disease Questionnaire scores. Moreover, the asleep technique was associated with more surgical adverse events, whereas pneumocephalus and psychological disorders such as mood, affect, and cognitive disorders were more common in the awake technique. Subgroup analyses revealed no significant differences in outcomes between asleep and awake DBS when categorized by targeted brain nuclei, use of intraoperative or preoperative imaging, and whether microelectrode recordings were used.

CONCLUSIONS
These findings suggest comparable clinical outcomes between the two DBS approaches. The two methods had their salient differences in terms of lead passes and specific adverse events. The decision to perform awake or asleep DBS should be based on the patient’s preference, the surgeon’s experience, the availability of advanced intraoperative imaging, and the patient’s tolerance for specific adverse events.
Assessing superficial temporal artery–middle cerebral artery anastomosis patency using FLOW 800 hemodynamics
Authors: Sangwon Karl L. , Nguyen Matthew , Wiggan Daniel D. , Negash Bruck , Alber Daniel A. , Liu Xujin Chris , Liu Albert , Rabbin-Birnbaum Corinne , Sharashidze Vera , Baranoski Jacob , Raz Eytan , Shapiro Maksim , Rutledge Caleb , Nelson Peter Kim , Riina Howard , Russin Jonathan , Oermann Eric K. , Nossek Erez 
Published: August 2024

OBJECTIVE
The objective of this study was to investigate the use of indocyanine green videoangiography with FLOW 800 hemodynamic parameters intraoperatively during superficial temporal artery–middle cerebral artery (STA-MCA) bypass surgery to predict patency prior to anastomosis performance.

METHODS
A retrospective and exploratory data analysis was conducted using FLOW 800 software prior to anastomosis to assess four regions of interest (ROIs; proximal and distal recipients and adjacent and remote gyri) for four hemodynamic parameters (speed, delay, rise time, and time to peak). Medical records were used to classify patients into flow and no-flow groups based on immediate or perioperative anastomosis patency. Hemodynamic parameters were compared using univariate and multivariate analyses. Principal component analysis was used to identify high risk of no flow (HRnf) and low risk of no flow (LRnf) groups, correlated with prospective angiographic follow-ups. Machine learning models were fitted to predict patency using FLOW 800 features, and the a posteriori effect of complication risk of those features was computed.

RESULTS
A total of 39 cases underwent STA-MCA bypass surgery with complete FLOW 800 data collection. Thirty-five cases demonstrated flow after anastomosis revascularization and were compared with 4 cases with no flow after revascularization. Proximal and distal recipient speeds were significantly different between the no-flow and flow groups (proximal: 238.3 ± 120.8 and 138.5 ± 93.6, respectively [p < 0.001]; distal: 241.0 ± 117.0 and 142.1 ± 103.8, respectively [p < 0.05]). Based on principal component analysis, the HRnf group (n = 10) was characterized by high-flow speed (> 75th percentile) in all ROIs, whereas the LRnf group (n = 10) had contrasting patterns. In prospective long-term follow-up, 6 of 9 cases in the HRnf group, including the original no-flow cases, had no or low flow, whereas 8 of 8 cases in the LRnf group maintained robust flow. Machine learning models predicted patency failure with a mean F1 score of 0.930 and consistently relied on proximal recipient speed as the most important feature. Computation of posterior likelihood showed a 95.29% chance of patients having long-term patency given a lower proximal speed.

CONCLUSIONS
These results suggest that a high proximal speed measured in the recipient vessel prior to anastomosis can elevate the risk of perioperative no flow and long-term reduction of flow. With an increased dataset size, continued FLOW 800–based ROI metric analysis could be used to guide intraoperative anastomosis site selection prior to anastomosis and predict patency outcome.
Nonquantitative CT scan Hounsfield unit as a determinant of cervical spine bone density
Authors: Fluss Rose , Lo Bu Riana , De la Garza Ramos Rafael , Murthy Saikiran G. , Yassari Reza , Gelfand Yaroslav 
Published: August 2024

OBJECTIVE
Hounsfield unit (HU) values measured using CT have been increasingly recognized to stand as a reliable corollary to dual-energy x-ray absorptiometry (DEXA) scores in evaluating bone mineral density. The authors examined the correlation between cervical HU values and DEXA T- and Z-scores and determined novel cervical HU thresholds for determining bone quality classification.

METHODS
One hundred patients who underwent both cervical spine CT and DEXA, 85 patients who underwent both lumbar CT and DEXA, and 128 patients who underwent cervical and lumbar CT within 24 months at a single institution were included in this retrospective review. Two independent reviewers collected HU values from 3 cervical vertebral levels (C4–6) and 4 lumbar vertebral levels (L1–4), and the averaged values were used. Pearson’s correlation coefficient analysis was performed to compare the association of cervical HU values with lumbar HU values and T- and Z-scores. The mean cervical HU values for each DEXA classification were calculated and compared. Receiver operating characteristic (ROC) curves were created to determine the threshold and its sensitivity and specificity for diagnosis.

RESULTS
Cervical (C4–6) HU values and average, lumbar, and femoral T- and Z-scores had significant correlations (0.436 > r > 0.274, all p < 0.01). A strong positive correlation between cervical and lumbar HU values was found (r = 0.79, p < 0.01). The average cervical HU value of healthy patients was 361.2 (95% CI 337.1–385.3); of osteopenic patients, 312.1 (95% CI 290.3–333.8); and of osteoporotic patients, 288.4 (95% CI 262.6–314.3). There was a significant difference between the cervical HU values of healthy and osteopenic patients (p = 0.0134) and between those of healthy and osteoporotic patients (p = 0.0304). The cervical HU value of 340.98 was 73.5% specific and 57.9% sensitive for diagnosing osteopenia with an area under the ROC (AUROC) curve of 0.655. The cervical HU value of 326.5 was 88.9% specific and 63.2% sensitive for diagnosing osteoporosis with an AUROC curve of 0.749.

CONCLUSIONS
This is the second large-scale study and first with a patient population from the United States to show that HU values obtained using cervical CT were significantly correlated with bone quality based on DEXA T- and Z-scores and to establish a cervical HU threshold for determining bone quality classification. These results show that cervical HU values can and should be used to predict poor bone quality in surgical cervical spine patients.
Predictors of patient satisfaction in the surgical treatment of cervical spondylotic myelopathy
Authors: Schupper Alexander J. , DiDomenico Joseph , Farber S. Harrison , Johnson Sarah E. , Bisson Erica F. , Bydon Mohamad , Asher Anthony L. , Coric Domagoj , Potts Eric A. , Foley Kevin T. , Wang Michael Y. , Fu Kai-Ming , Virk Michael S. , Shaffrey Christopher I. , Gottfried Oren N. , Park Christine , Knightly John J. , Meyer Scott , Park Paul , Upadhyaya Cheerag , Shaffrey Mark E. , Chan Andrew K. , Tumialán Luis M. , Chou Dean , Haid Regis W. , Mummaneni Praveen V. , Uribe Juan S. , Turner Jay D. 
Published: August 2024

OBJECTIVE
Patients with cervical spondylotic myelopathy (CSM) experience progressive neurological impairment. Surgical intervention is often pursued to halt neurological symptom progression and allow for recovery of function. In this paper, the authors explore predictors of patient satisfaction following surgical intervention for CSM.

METHODS
This is a retrospective review of prospectively collected data from the multicenter Quality Outcomes Database. Patients who underwent surgical intervention for CSM with a minimum follow-up of 2 years were included. Patient-reported satisfaction was defined as a North American Spine Society (NASS) satisfaction score of 1 or 2. Patient demographics, surgical parameters, and outcomes were assessed as related to patient satisfaction. Patient quality of life scores were measured at baseline and 24-month time points. Univariate regression analyses were performed using the chi-square test or Student t-test to assess patient satisfaction measures. Multivariate logistic regression analysis was conducted to assess for factors predictive of postoperative satisfaction at 24 months.

RESULTS
A total of 1140 patients at 14 institutions with CSM who underwent surgical intervention were included, and 944 completed a patient satisfaction survey at 24 months postoperatively. The baseline modified Japanese Orthopaedic Association (mJOA) score was 12.0 ± 2.8. A total of 793 (84.0%) patients reported satisfaction (NASS score 1 or 2) after 2 years. Male and female patients reported similar satisfaction rates (female sex: 47.0% not satisfied vs 48.5% satisfied, p = 0.73). Black race was associated with less satisfaction (26.5% not satisfied vs 13.2% satisfied, p < 0.01). Baseline psychiatric comorbidities, obesity, and length of stay did not correlate with 24-month satisfaction. Crossing the cervicothoracic junction did not affect satisfactory scores (p = 0.19), and minimally invasive approaches were not associated with increased patient satisfaction (p = 0.14). Lower baseline numeric rating scale neck pain scores (5.03 vs 5.61, p = 0.04) and higher baseline mJOA scores (12.28 vs 11.66, p = 0.01) were associated with higher satisfaction rates.

CONCLUSIONS
Surgical treatment of CSM results in a high rate of patient satisfaction (84.0%) at the 2-year follow-up. Patients with milder myelopathy report higher satisfaction rates, suggesting that intervention earlier in the disease process may result in greater long-term satisfaction.
Longitudinal analysis of cranial growth using comprehensive craniometric measurements after fronto-orbital advancement in coronal craniosynostosis
Authors: Jeon Sungmi , Lee Se Yeon , Oh Albert K. , Yoon Taekeun , Chung Jee Hyeok , Kim Sukwha , Kim Seung-Ki , Phi Ji Hoon , Lee Ji Yeoun , Kim Kyung Hyun , Kim Byung Jun 
Published: August 2024

OBJECTIVE
The objective of this study was to investigate the longitudinal changes in cranial growth following fronto-orbital advancement (FOA) surgery in patients with unilateral and bilateral coronal craniosynostosis.

METHODS
This retrospective review analyzed head circumference (HC) and CT data during preoperative (T0), immediate postoperative (T1), and final follow-up (T2) visits in 40 patients (23 female, 17 male) who underwent FOA using either the open approach or distraction osteogenesis (DO) between 1987 and 2018. The mean follow-up period was 90.62 months. The z-scores of HC, CT-based intracranial volume, anteroposterior diameter (APD), biparietal diameter (BPD), and cranial height (CH) were calculated using sex- and age-specific standards. Logistic regression analysis was performed.

RESULTS
While the z-scores of HC, intracranial volume, and BPD remained within the normal range, the z-scores of APD fluctuated between −2 and −1, and the z-scores of CH were > 2, indicating a substantial elevation compared with norms from T0 to T2. Age at surgery significantly influenced the z-scores of HC, BPD, and CH at T2 (all p < 0.05). Delayed surgical timing was correlated with increased BPD and CH z-scores from T1 to T2 (p = 0.007 and 0.019, respectively). The DO for FOA resulted in elevated HC z-scores at T2 and increased APD from T0 to T1, followed by a significant APD relapse from T1 to T2.

CONCLUSIONS
These findings suggest that delayed surgical timing may support better cranial growth, as indicated by increased HC at long-term follow-up. However, delayed timing is also associated with worsening abnormally elevated CH. Despite the immediate APD expansion and long-term HC increase with DO, potential relapse warrants caution. While intentional overcorrection of APD is recommended, careful consideration of surgical timing and planning is essential.
Pengaruh Kualitas Sumberdaya Manusia Di Bidaang Akuntansi, Sistem Pengendalian Internal Dan Pemanfaatan Teknologi Informasi Terhadap Kualitas Laporan Keuangan Pada Koperasi Simpan Pinjam Di Kecamatan Denpasar Timur
Authors: Wicaksana I Gede Eka Dharma , Yuniasih Ni Wayan , Pratiwi Putu trisna Windika 
Published: August 2024

Purpose of study purpose is forthis is for identify how the attribute of a person accounting resources, internal control mechanisms, and utilization of informationmechanisms, and utilization of information technology affect the quality of financial reports. This research involved taff member of the savings and loan cooperative in East Denpasar District, with a total of 91 respondents. This research was conducted quantitatively. Linear regression, multiple regression, coefficient of determination, F test, and t test were used in this study. The coefficient of determination, F test, and t test were used in this study. The research results show that the quality of human resources in the accounting field accumulates positively and significantly with the quality of financial reports; a positive and significant internal control system with the quality of financial reports; and the use of technology stores information positively and significantly with the quality of financial reports. Researchers suggest that cooperatives in East Denpasar District regularly provide training to their employees to improve their ability to prepare financial reports, be consistent and honest in implementing internal control systems, and always update the use of technology.
Nutritional quality and price of plant-based dairy and meat analogs in the Canadian food supply system
Authors: Lee Jenn , Srebot Sophia , Ahmed Mavra , Mulligan Christine , Hu Guanlan , L’Abbé Mary R. 
Published: August 2024

<p>There has been an increased consumer interest and public health emphasis on plant-based protein foods, resulting in a rise in the availability of highly processed plant-based analogs. The objectives of this study were to assess the nutritional quality and the price of plant-based dairy and meat analogs compared to their respective animal-derived products and to examine the association between processing levels and the nutritional quality among these products. Using a branded food composition database, products in cheese, yogurt, milk, and meat categories were examined (n = 3231). Products were categorized as plant-based analogs versus animal-derived products using the ingredient list. Products were examined for their nutrient content, overall nutritional quality using the Food Standards Australia New Zealand nutrient profiling model, price, and processing levels using the NOVA classification. All plant-based analogs had lower protein and higher total carbohydrate, sugar, and fiber content compared to their respective animal-derived products. Compared to their respective animal-derived products, plant-based milk and meat analogs had lower energy, total fat, and saturated fat content; plant-based yogurt and meat analogs had lower sodium content; and all plant-based dairy analogs had lower calcium content. Plant-based cheese and yogurt analogs were more expensive than animal-based products; however, there was no significant difference among milk and meat products. There was no association between processing levels and overall nutritional quality among dairy and meat products. Plant-based analogs may be part of a healthy and affordable diet to reduce the intakes of nutrients of concern; however, additional compositional guidelines and/or labeling may be needed to highlight the differences in the levels of nutrients to encourage. </p>
Effect of potatoes and other carbohydrate-containing foods on cognitive performance, glycemic response, and satiety in children
Authors: Lee Jenn , Brett Neil R. , Wong Vincent C.H. , de Zepetnek Julia O Totosy , Fiocco Alexandra , Bellissimo Nick 
Published: August 2024

<p>Dietary carbohydrates have been shown to influence cognitive performance and satiety in children. However, it remains unclear whether the carbohydrate source is a primary determinant of cognitive performance and satiety. The objective was to compare the effects of white potatoes and other carbohydrate-containing foods on cognitive performance, glycemic response, and satiety in children. On 6 separate mornings, in random order, children (<em>n</em> = 22) consumed 50 g of available carbohydrates from microwaved mashed potatoes (prepared from fresh potatoes then frozen), deep-fried potato strips (French fries), hash browns, white rice, white beans, or skipped a meal. Cognitive performance, glycemic response, and satiety were measured over 180 min. Cognitive performance was measured using a battery of tests assessing verbal declarative memory, spatial memory, short-term memory, working memory, and information processing speed. Although cognitive performance after the treatment meals did not differ from meal skipping, children recalled more words after French fries (9.1 ± 0.4 words) compared with mashed potatoes (8.2 ± 0.3 words; <em>p</em> = 0.001) and white rice (8.4 ± 0.3 words; <em>p</em> = 0.04) on the verbal declarative memory test. Blood glucose concentrations were higher after white rice compared with white beans, mashed potatoes, and hash browns (<em>p</em> < 0.05). Change from baseline subjective average appetite (mm/kcal) was lower after mashed potatoes compared with all other treatment meals (<em>p</em> < 0.05). In conclusion, verbal declarative memory was higher after French fries and subjective average appetite was lower after mashed potatoes. Future longitudinal studies are needed to confirm these short-term findings and to elucidate the mechanism of action. </p>
EDUKASI TERHADAP TINGKAT PENGETAHUAN IBU DALAM SWAMEDIKASI PENANGANAN DEMAM PADA ANAK DI KELURAHAN RANGKAPAN JAYA
Authors: Daniswara Monna Aisya , Humaedi Aji , Lukitasari Nurraya 
Published: August 2024

PENDAHULUAN : Demam merupakan masalah kesehatan terutama di Indonesia. Swamedikasi demam pada anak sangat bergantung pada peran orang tua, terutama ibu. Kesalahpahaman dalam mengobati demam memicu fever phobia. Penelitian ini bertujuan untuk mengetahui pengaruh edukasi berupa penyuluhan terhadap tingkat pengetahuan ibu tentang demam pada anak dan cara pengobatannya.METODE : Penelitian ini menggunakan metode Pre-Experimental Designs yaitu dengan menggunakan One-Group Pretest-Posttest Design. Sampel penelitian diperoleh dengan menggunakan metode purposive sampling sebanyak 90 responden. Tingkat pengetahuan diperoleh melalui pengisian angket pada saat pre-test dan post-test. Penyuluhan dilaksanakan dengan metode ceramah dengan penyebaran leaflet. Analisis data angket menggunakan uji Wilcoxon.HASIL DAN PEMBAHASAN : Hasil penelitian menunjukkan bahwa tingkat pengetahuan responden sebelum penyuluhan sebesar 67,2% (Cukup) dan setelah dilakukan penyuluhan sebesar 97,6% (Baik). Hasil uji menunjukkan terdapat peningkatan yang signifikan pada pengetahuan tentang swamedikasi demam pada anak sebelum dan sesudah penyuluhan dengan (p=0,000). KESIMPULAN : Disimpulkan bahwa penyuluhan tentang swamedikasi demam pada anak berdampak besar terhadap peningkatan pengetahuan Ibu sebesar 30,4%.
Keanekaragaman Gastropoda Berdasarkan Karakteristik Habitat pada Ekosistem Mangrove Kota Langsa
Authors: Apriyanti Dewi , Suciaty Endah , Simamora Mei Sarah , Purba Ruth Helena 
Published: August 2024

Gastropoda merupakan salah satu hewan yang hidup di ekosistem mangrove dan berperan dalam penguraian serasah. Tujuan dari penelitian ini untuk memberikan informasi terkait keanekaragaman gastropoda dalam menjaga keseimbangan ekosistem mangrove Kota Langsa. Penelitian ini bersifat deskripsi eksploratif dengan menggunakan metode transek. Hasil dari penelitian terdapat 12 spesies termasuk 7 family gastropoda yang ditemukan. Setiap stasiun dikawasan penelitian memiliki karakteristik yang bervariasi sehingga mempengaruhi keragaman spesiesnya. Indeks keanekaragaman yang didapatkan berkisar 1,18 hingga 2,13.
Kajian Literature: Penerapan Project Based Learning terkait Tujuan Pembangunan Berkelanjutan Poin 2 untuk Meningkatkan Kemampuan Berpikir Kreatif dan Kolaborasi Siswa
Authors: Amalia Indriyani , Riandi Riandi , Surtikanti Hertien Koosbandiah 
Published: August 2024

Perkembangan dunia pendidikan seiring berjalannya waktu semakin menunjukan adanya kemajuan, yang berdampak pada hasil pembelajaran. Hal ini juga berdampak pada perkembangan model pembelajaran yang dilakukan untuk memenuhi capaian yang sesuai dengan perkembangan zaman. Perkembangan model pembelajaran yang salah satunya terus dikembangkan adalah model project based learning. Penggunaan project based learning digunakan, guna menjadi salah satu perkembangan model pembelajaran yang dapat mencapai tujuan pendidikan yaitu keterampilan abad 21. Artikel ini dilakukan dengan mengumpulkan artikel sebanyak 16 artikel yang terindeks scopus dari berbagai negara, yang berkaitan dengan project based learning, project based learning yang berkaitan dengan pencapaian SDGs poin 2 (Zero Hunger), keterampilan berpikir kreatif dan kolaborasi. Metode yang digunakan dalam artikel ini yaitu study literature review. Artikel ini bertujuan untuk mendeskripsikan penerapan Project Based Learning dalam pencapaian SDGs poin 2 (Zero Hunger) dalam meningkatkan kemampuan berpikir kreatif dan kolaborasi. Hasil dari artikel ini mengungkapkan informasi mengenai Project Based Learning, Penerapan Project Based Learning yang berkontribusi dalam pencapaian SDGs poin 2 ((Zero Hunger), kemampuan Berpikir kreatif dalam PjBL dan kemampuan kolaborasi dalam PjBL. Kemudian menyebutkan beberapa artikel yang menggunakan Project Based Learning dalam mengintegrasikannya pada pencapaian SDGs poin 2 (Zero Hunger) dengan membuat inovasi pada produk pangan dan pemanfaatn hasil petani lokal. Selanjutnya mengemukakan penerapan Project Based Learning dapat mengembangkan proses berpikir kreatif dan kolaborasi pada siswa. Sehingga artikel ini dapat menjadi informasi dan menjadi sebuah ide yang dapat dikembanglan dari penerapan Project Based Learning dalam mencapai poin SDGs lainnya yang saat ini perlu kita realisasikan bersama.