bluuebunny/crossref_metadata_2025_split huggingface dataset:
An in vitro assessment of optimizing implant positions in bilateral distal extension implant-assisted removable partial dentures: A microstress analysis
Authors: Bhattacharya Dipayan , Ponnanna A.A , Jingade Ranganatha Rao K. , Maiti Subhabrata , Rai Nitesh , Gopalkrishna Muralidhar 
Published: August 2024

Aim:
The aim of this study was to analyze and compare the stress distribution on dental implants in various positions when used with implant-assisted removable partial dentures.

Settings and Design:
This was an in vitro study.

Materials and Methods:
A model representing a mandibular bilateral partially edentulous condition, with missing premolars and molars, was fabricated using epoxy resin. Two implants of similar diameter measuring 4.0 mm × 10 mm (Dentium, Korea) were inserted in the second molar and the second premolar region on either side of the model for comparing the biomechanical effect of various implant locations. Two types of loads 100N and 125N were applied vertically using universal testing machines in the premolar and molar regions. The loads on the implants beneath the cast partial denture were measured by physical stress analysis using a microstrain gauge.

Statistical Analysis Used:
A comparison of maximum stress observed at the premolar versus molar regions due to the application of the 100N and 125N loads was done using the Mann–Whitney U-test.

Results:
In physical stress analysis, obtained results were statistically analyzed, and the result was statistically not significant (P = 0.435 at 100N and P = 0.718 at 125N) in positional changes of implant.

Conclusion:
In the current study, the statistical analysis of physical stress revealed no significant differences in stress values between the loadings at the premolar and molar regions. This suggests that the implant can be placed in either the premolar or molar region based on the availability of bone without affecting stress distribution.
Evaluation of marginal bone level, technical and biological complications between screw-retained and cement-retained all-ceramic implant-supported crowns on zirconia abutment: A systematic review and meta-analysis
Authors: Potdukhe Shruti S. , Iyer Janani M. , Nadgere Jyoti B. 
Published: August 2024

Purpose:
The purpose of this study was to evaluate the difference in marginal bone level, technical and biological complications between screw-retained and cemented all-ceramic implant-supported crowns fabricated on zirconia abutment at different follow-up periods.

Materials and Methods:
Independent search was conducted in Cochrane Library, EBSCO, and PubMed/PubMed Central/MEDLINE databases and the Google Scholar search engine for prospective studies and randomized controlled trials published between January 2014 and June 2023 evaluating the marginal bone level, technical and biological complications between screw-retained and cemented all-ceramic implant-supported crowns fabricated on zirconia abutment. Meta-analysis was conducted to assess the quantitative data on the marginal bone level and biological complications.

Results:
A total of eight studies were included for qualitative synthesis and six studies for quantitative synthesis. For marginal bone level, no statistically significant difference was observed (P = 0.83 and P = 0.69, respectively) during the follow-up period of 3 years and 5 years. For probing depth, the cemented group showed more amount of probing depth than the screw-retained group at a follow-up period of 3 years (P < 0.05) whereas no statistically significant difference was observed at a follow-up period of 5 years (P = 0.73). For bleeding on probing, the cemented group showed more probing depth than the screw-retained group at a follow-up period of 5 years (P = 0.10).

Conclusion:
The evidence suggests that the screw-retained group showed no statistically significant difference in marginal bone level, comparatively fewer biological complications, and relatively higher technical complications than the cemented group at different follow-up periods.
Vesical Endometriosis in a male patient on treatment for papillary urothelial carcinoma
Authors: Sarkar Pallab Kumar , Koslowski Matthias , Streeter Edward 
Published: August 2024

Abstract
Endometriosis denotes the abnormal growth of tissue resembling endometrium in ectopic sites and has largely been studied in women of reproductive age. It is an extremely rare phenomenon in men. We came across an exceptional clinical scenario of histologically proven bladder endometriosis in a 66-year-old man in relook bladder biopsy following completion of adjuvant intravesical Bacillus Calmette-Guerin induction course for G3pTa bladder cancer. We have pencilled down pathophysiology and commonly seen predisposing factors for “endometriosis in male patients” from available case reports and applied those findings to hypothesise the disease profile of our patient in this case report.
Internist’s tumour into thyroid: A case report
Authors: Sarkar Pallab Kumar , Nissanka-Jayasuria Eranga , Eraibey Muhammad , Kommu Sashi 
Published: August 2024

AbstractRenal cell carcinoma (RCC) is well known for its unpredictable and diverse behaviour, with tendency to cause synchronous or metachronous metastasis to unusual site, which is why it is called the “internist’s tumour.”Although thyroid gland is an infrequent site for metastasis of different primary malignancies, metastatic RCC is one of the most common secondary thyroid malignancies. Diagnosis relies on a high index of suspicion in patients with prior RCC, combined with cross-sectional imaging and biopsy. A case of secondary thyroid neoplasm from RCC after 13 years of radical nephrectomy is described with clinicopathological features and literature review.
Optical iridectomy: A stop-gap for penetrating keratoplasty in a resource-limited setting
Authors: Ocheni Samuel Enejo , Oseji Daniel Ikechukwu , Megbelayin Emmanuel Olu , Adepoju Feyi Grace 
Published: August 2024

Abstract
Corneal opacities are a major source of corneal morbidity in Africa and many resource-limited parts of the world. Unfortunately, there is a dearth of specialist corneal services either from lack of manpower or non-availability of materials and tools. This makes penetrating keratoplasty inaccessible from prohibitive cost or lack of donors. The index case was a 45-year-old indigent female farmer who presented with a right atrophic eye and defective vision on the left eye due to stick injury from farm work. Examination revealed a 2/60 eccentric vision and extensive adherent leukoma on the left eye. Superonasal optical iridectomy was done and vision improved to 6/18 with correction at sixth postoperative week. In conclusion, optical iridectomy, in selected patients, can restore useful vision.
Comparing the effects of pre-emptive oxycodone, diclofenac, and gabapentin on postoperative pain after tibia fracture surgery: A randomized clinical trail
Authors: Abrishami Ramin , Ranjbar Mehri Farhang , Modir Amirreza , Hejazi Seyyed Kamal 
Published: August 2024

Abstract

Background:
Postoperative pain (POP) is one of the most common and most important types of pain.

Objectives:
The aim of this study was to compare the effects of pre-emptive oxycodone, diclofenac, and gabapentin on postoperative pain (POP) among patients with tibia fracture surgery.

Materials and Methods:
This double-blind three-group randomised controlled trial was conducted in 2023. Participants were 111 candidates for tibia fracture surgery under general anaesthesia. They were randomly allocated to oxycodone, gabapentin, and diclofenac groups through block randomisation. Baseline arterial oxygen saturation, heart rate, and blood pressure were documented before surgery and POP and sedation status were measured during postoperative recovery and 2, 4, 6, 12, and 24 h after surgery. Postoperative opioid analgesic use was also documented. The data were analysed using the SPSS software (v. 20.0) at a significance level of less than 0.05.

Results:
Groups did not significantly differ from each other respecting participants’ baseline age, gender, body mass index, arterial oxygen saturation, heart rate, blood pressure, and surgery duration (P > 0.05). Moreover, there were no significant differences among the groups respecting POP and sedation status at different measurement time points (P > 0.05), except for six hours after surgery at which the POP mean score in the gabapentin group was significantly less than the other two groups (P = 0.001). Among-group differences respecting postoperative use of opioid analgesics and medication side effects were also insignificant (P > 0.05).

Conclusion:
Pre-emptive oxycodone, diclofenac, and gabapentin significantly reduce POP among patients with tibia fracture surgery, though gabapentin may produce more significant analgesic effects. All these three medications can be used for pre-emptive analgesia. Of course, the best pre-emptive analgesic agent is determined based on the opinion of the treating physician.
Assessment of shoulder joint derangements with magnetic resonance imaging in adult Nigerians
Authors: Idowu Bukunmi Michael , Onigbinde Stephen Olaoluwa , Afolabi Babalola Ishmael , Ogholoh Oghenetejiri Denise , Nwafor Nkem Nnenna , Okedere Tolulope Adebayo 
Published: August 2024

Abstract

Objectives:
Shoulder pain secondary to various aetiologies is a common musculoskeletal complaint worldwide, and Magnetic Resonance Imaging (MRI) is the most accurate imaging method for evaluating shoulder pain in all age groups. While the patterns of shoulder MRI abnormalities in various demographics have been reported, data on sub-Sahara African populations are still sparse. This study aims to describe the imaging features and spectrum of shoulder joint pathologies on MRI in adult Nigerians.

Materials and Methods:
This was a retrospective review of the shoulder MRI of 100 adult Nigerians (with and without trauma) from September 2020 to December 2021. Their clinical data and shoulder MRI findings were extracted and analysed. Statistical significance was set at P ≤ 0.05.

Results:
There were 64 males and 36 females aged 18–82 years. Right shoulder MRI was done in 53 subjects (53%), while the left shoulder was studied in 47 (47%). Supraspinatus tendinopathy (73%), acromioclavicular joint arthropathy (68%), and subacromial-subdeltoid (SASD) bursitis (64%) were the most frequently detected pathologies. Other demonstrated derangements include glenohumeral joint effusion (24%), long head of biceps tendon sheath effusion (18%), labral abnormalities (16%), subcoracoid bursitis (4%), Hill Sach’s deformity (3%), anterior glenohumeral dislocation (2%), fatty degeneration of the supraspinatus/infraspinatus muscles (2%), adhesive capsulitis (1%), and other bony abnormalities (contusion, erosion, subchondral cysts). There was no significant difference in the frequency of shoulder abnormalities between the male and female subjects.

Conclusion:
Acromioclavicular joint arthropathy, SASD bursitis, and rotator cuff disorders were the dominant pathologies in the participants’ shoulders.
Domestic violence against women with infertility attending gynaecological clinics in Northern Nigeria: A multi-centre study
Authors: Ashimi Adewale Olufemi , Aminu Muhammad Baffah , Adewale Folorunsho Benard , Abdurrahman Aisha , Muhammad Yunus Eze 
Published: August 2024

Abstract

Background:
Due to the high premium placed on childbearing, infertility puts a lot of stress on the family which may result in aggressive and irrational behaviour if not properly managed. Domestic violence (DV) against infertile women is a public health issue but under-reported especially in northern Nigeria.

Objectives:
This study sought to identify the prevalence, pattern, and response to DV.

Materials and Methods:
This was a descriptive cross-sectional study carried out at three tertiary health facilities; one in each of the geopolitical zones in northern Nigeria. Using a pretested interviewer-administered questionnaire; the prevalence, pattern, and response to DV were determined among 422 respondents who were attending the gynaecological clinics of the three health facilities. The data obtained was entered into SPSS version 22.0 and analysed.

Results:
The prevalence of DV among women with infertility in the previous year was 39.8% (167/422). Among the survivors, 92.8% (155/167), 35.3% (59/167), and 10.7% (18/167) had experienced psychological aggression, physical assault, and sexual violence, respectively. A significant number of respondents who reported DV were Christians (P = 0.01). Of them, 77 (46.1%) never discussed the issue with anyone, 72 (43.1%) informed their family, and 30 (18.0%) sought help from the husband’s family.

Conclusion:
The prevalence of DV among women with infertility is high, psychological aggression is the most typical form of DV experienced while about half have never reported the incidence to anyone. Screening infertile women for DV during their visit to the gynecological clinics would be beneficial; those found to have experienced DV should be counselled and supported appropriately.
Management of painful blind eye in Africa: A review
Authors: Kayoma Dumebi Hedwig , Oronsaye Darlingtess Abies 
Published: August 2024

Abstract

Background:
Painful blind eye conditions in Africa constitute a compelling area of concern within public health, presenting substantial complexities for healthcare systems and the individuals afflicted. This comprehensive review delves into recent research and advancements concerning the management of these conditions across the African region. Drawing upon contemporary studies and data, we scrutinise the multifaceted aspects, including prevalence rates, causative factors, and regional variations.

Objective:
To review existing articles on the current state of the management of blind painful eye conditions in Africa.

Materials and Methods:
Articles regarding the subject were obtained from Google Scholar, AJOL, and PubMed using the keywords, painful, blind eye (PBE), Africa.

Results:
Forty-four relevant articles were reviewed. They were further categorized into epidemiology, management approaches and challenges to management.

Conclusion:
The management of the PBE poses a huge challenge and can either be medical or surgical. Collaborative efforts should be targeted at preventing the causes of a PBE. As the burden of painful blind eye conditions continues to exert a profound impact across Africa, this article underscores the pressing need for collaborative efforts involving governments, non-governmental organisations, and international entities. By prioritising awareness and enhancing healthcare accessibility, we collectively strive towards the alleviation of suffering and the prevention of avoidable visual impairment in this region.
Spectrum of carotid arterial Doppler abnormalities among stroke patients at a tertiary care centre in North West Nigeria
Authors: Hikima Mustapha Shu’aibu , Lawal Yusuf , Isyaku Kabir , Kazaure Idris Sule , Suwaid Muhammad Abba , Ismail Anas 
Published: August 2024

Abstract

Background:
Stroke is the second most common cause of death worldwide. It also represents one of the most common causes of disability, affecting both children and adults. The identification of risk factors for stroke is critical in preventing its occurrence. Carotid atherosclerosis is one of the most significant risk factors of stroke, yet it is not routinely evaluated in these patients.

Materials and Methods:
We prospectively recruited 119 patients aged ≥18 years with stroke confirmed by computed tomography scan. The risk factors for stroke in these patients were identified, and carotid artery Doppler was performed to identify those with atherosclerosis.

Results:
Eighty-one (68%) of the 119 subjects showed abnormalities in the carotid arteries in the form of increased IMT or atheromatous plaque. The mean ± SD IMT of the right common carotid artery (CCA) was 1.07 ± 0.25 mm and 1.08 ± 0.26 mm for the left CCA. The IMT mean ± SD of the right and left ICA were 0.99 ± 0.18 mm and 0.99 ± 0.17 mm, respectively. There were 36 patients (30.2%) with atheromatous plaques, of which 57.8% were unstable and liable to rupture. The carotid bulbs were the most common sites for plaques, accounting for 47.2% of cases. No abnormalities in velocimetric indices were recorded.

Conclusion:
Carotid atherosclerosis is common in stroke patients and is a major risk factor. The evaluation of stroke patients for carotid atherosclerosis is rarely done, as most of the subjects examined only had it for the first time in this study after development of stroke.
A comparison of fascia iliaca compartment block with intravenous analgesia to improve pain control in patients with femoral fracture
Authors: Usman Mohammed Adinoyi , Rabiu Mohammed Bashir , Salahu Dalhat 
Published: August 2024

Abstract

Background:
The most common approach to managing severe pain following femoral fracture is with intravenous systemic analgesics, such as opioid analgesics and non-steroidal anti-inflammatory drugs associated with side effects such as respiratory depression, nausea, and vomiting. These side effects might be intolerable in trauma patients and may result in under treatment of pain. Improving the quality of analgesia may reduce these intolerable side effects. Our study compared the efficacy of fascia iliaca compartment block (FICB) with intravenous analgesics for preoperative pain management of femoral fractures.

Patients and Methods:
The study was a quality improvement prospective randomised study, where 50 patients aged between 18 and 65 years, and American society of anesthesiologists I and II were recruited into two groups. Group A received FICB with a combination of 0.4 mL/kg of 0.5% plain bupivacaine and adrenaline 1:200,000 made up to 30 mL, while group B received placebo FICB using 30 mL normal saline. Also, group B received a combination of intravenous paracetamol 15 mg/kg not exceeding 900 mg and tramadol 1 mg/kg not exceeding 100 mg, while group A received an equal volume as normal saline intravenously.

Results:
The study revealed no significant difference in age, gender, associated injuries, X-ray description of fractures, and mechanism of injuries; however, there was a significant difference in the NRS-pain score at 30 min, summed pain intensity difference for 4 h and patient satisfaction in the FICB group compared to the standard group.

Conclusion:
The study revealed that FICB results in better pain control compared to a combination of intravenous tramadol and paracetamol in patients with femoral fractures.
An Adult with Acute Breathlessness and Unilateral Diffuse Alveolar Opacities
Authors: Gowrinath Karanam , Reddy Chirra Bhakthavatsala 
Published: August 2024

Abstract
Cardiogenic pulmonary edema is typically bilateral and results from the accumulation of excessive fluid in the interstitial and alveolar spaces of the lungs caused by left ventricular failure. Cardiogenic unilateral pulmonary edema (CUPE) is uncommon and most often documented in severe mitral regurgitation. CUPE in other cardiac diseases such as coronary artery disease is rare and occasionally associated with prolonged lateral decubitus position or vascular perfusion mismatch between lungs either congenital such as pulmonary artery agenesis or acquired due to preexisting lung conditions such as compensatory emphysema following lobectomy. The radiologic opacities of CUPE does not have characteristic features as described with bilateral pulmonary edema. The possibility of CUPE is often not considered initially as its clinical/radiologic features often resemble or are mistaken as pneumonia resulting in diagnostic delay and higher mortality.
Evaluation of Prevalence and Patterns of Oncogenic Driver Mutations in Nonsmall Cell Lung Cancer in a Tertiary Care Center - A Cross-sectional Study
Authors: Kozhikodenveettil Shilpa Thippilikkat , Azeez Ameer Karavathukudy 
Published: August 2024

Abstract

Background:
Better understanding of the molecular pathways that drive malignancy led to the development of agents that target specific molecular pathways that target the malignant cells. Identification of specific driver mutation is the key to targeted therapy in advanced nonsmall-cell carcinomas. This study was done to assess the prevalence and patterns of driver oncogenic mutations in nonsmall cell lung cancer (NSCLC) among the patients subjected to molecular study in a tertiary care center.

Materials and Methods:
This is a cross-sectional study done in 1.5 years in a tertiary care center in 103 patients diagnosed with NSCLC. Patients with NSCLC were subjected to molecular study in the department of oncology as a part of management. The demographics, clinical details, laboratory parameters, and pathology were noted from the medical records. The molecular study was done from the biopsied specimen in an outside laboratory. The frequency of driver oncogenic mutation, along with other clinical parameters was studied.

Results:
Out of 103 patients subjected to the study, 46 (44.6%) subjects had driver oncogenic mutations. Among them, 38 (36.9%) subjects had epidermal growth factor receptor mutations, 7 (6.8%) had anaplastic lymphoma kinase mutations, and 1 (1%) had ROS mutation.

Conclusion:
The frequency of driver oncogenic mutations is higher in our population, compared to the Western population. From a clinical point of view, there is a dire need for advocacy and increased awareness for screening and early detection of thoracic malignancies, and advanced treatment options, including targeted therapy, so that disease-related morbidity and mortality can be reduced to an extent.
Conjunctival impression cytology and tear film changes in patients with type 2 diabetes mellitus and its correlation with severity of diabetic retinopathy
Authors: Sahu Juhi , Vallinayagam Muthukrishnan , Srikanth Krishnagopal , Srini Sowmya 
Published: August 2024

Abstract:

PURPOSE:
Dry eye symptoms can substantially affect the quality of life and visual outcome. There are several studies on ocular surface changes reported in diabetic patients. There is limited literature defining the relationship between dry eye with diabetic retinopathy (DR). The study aimed to find out the correlation of dry eye with the severity of DR.

METHODS:
In a cross-sectional observational study, we recorded the grading of dry eye in patients with DR on Schirmer’s, tear film breakup time (TBUT), and impression cytology. We correlated the severity of dry eye with the severity of retinopathy using Spearman’s correlation and Kruskal–Wallis test. We also found a significant correlation between glycemic control and the severity of dry eye. P < 0.05 was considered statistically significant.

RESULTS:
One hundred and eighty-four eyes of 96 patients with DR were assessed. One hundred and fifty-eight eyes with nonproliferative DR and thirty-four eyes with proliferative DR were included in the study. Mean Schirmer’s and TBUT values were 15.4 ± 5.8 mm and 10.1 ± 2.8 s, respectively. Average impression cytology grade on Modified Nelson’s grading was found to be Grade 3. A positive correlation was found between the severity of dry eye with the severity of DR on Schirmer’s, TBUT, and impression cytology.

CONCLUSION:
Diabetics with severe grades of retinopathy had poor tear function along with compared to those with milder grades of DR. Hence, routine screening of the ocular surface should become a part of diabetic eye evaluation.