bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengenalan Penyakit Rabies dan Vaksinasi Rabies di Lingkungan RW 01 Kramat Jati, Jakarta Timur
Authors: A'ini Zakiah Fithah , Alfy Zuhana Realita , Soenarno Sri Murni 
Published: July 2024

Kegiatan pengabdian kepada masyarakat yang dilaksanakan di lingkungan RW 01 Kramat Jati, Jakarta Timur, bertujuan untuk meningkatkan kesadaran dan pengetahuan warga mengenai bahaya penyakit rabies serta pentingnya vaksinasi hewan peliharaan. Program ini terdiri dari empat tahap. Dimulai dari tahap persiapan yang dilakukan selama 2 minggu, tahap sosialisasi dan edukasi yang dibantu oleh kader PKK, tahap pelaksanaan vaksinasi yang bekerjasama dengan Puskesmas kecamatan Kramat Jati, dan monitoring serta evaluasi yang dilakukan bersama dengan tim dan kader PKK. Hasil kegiatan menunjukkan bahwa warga merespon positif terhadap program ini, dengan tingginya tingkat partisipasi dan penerimaan terhadap vaksinasi hewan di lingkungan RW 01, yaitu sebanyak 64 hewan peliharaan dan liar telah divaksinasi. Jika berpedoman pada survei awal, yaitu 76 hewan peliharaan dan liar maka kegiatan ini telah berhasil memvaksinasi 84,2% hewan di lingkungan RW 01 Kramat Jati, Jakarta Timur. Maka dapat disimpulkan bahwa kegiatan ini berhasil meningkatkan kesadaran masyarakat akan pentingnya vaksinasi rabies yang dapat menekan penyebaran penyakit rabies.
STRATEGI GURU PENDIDIKAN AGAMA ISLAM DALAM MEMBINA AKHLAKUL KARIMAH SISWA DI SD NEGERI 106826 DESA SIDODADI
Authors: Dewi Ricka Puspita , Mukti Abdul , Haidir Haidir 
Published: July 2024

Tujuan penelitian ini adalah untuk mengetahui bentuk-bentuk akhlakul karimah siswa yang dikembangkan oleh guru PAI di SDN 106826 Desa Sidodadi Kecamatan Batang Kuis dan strategi guru PAI dalam menanamkan akhlakul karimah siswa di SDN 106826 Desa Sidodadi Kecamatan Batang Kuis. Penelitian ini menggunakan metode penelitian kualitatif deskriptif dengan teknik pengumpulan data melalui wawancara, observasi dan dokumentasi. Data dan sumber data diperoleh dari data primer dan data sekunder Analisis data yang digunakan adalah analisis data kualitatif dengan reduksi data, penyajian data dan penarikan kesimpulan. Hasil penelitian menunjukkan bahwa bentuk akhlakul karimah siswa yang dikembangkan di SD Negeri 106826 yaitu amanah dan adab. Tata krama disini adalah menghormati orang tua dan guru serta menyayangi sesama. Dalam hal penanaman akhlakulkarimah pada peserta didik, guru pendidikan agama Islam dalam hal ini melakukan usaha atau tindakan sendiri dalam menanamkan nilai-nilai kebaikan pada peserta didik. Strategi yang dilakukan oleh guru adalah keteladanan dan pembiasaan, nasehat, bimbingan, motivasi dan hukuman.<p> </p>
PENGARUH MEDIA PEMBELAJARAN ONLINE BERBASIS APLIKASI GOOGLE MEET TERHADAP PEMBELAJARAN AGAMA ISLAM DI PRODI PJKR UPMI MEDAN
Authors: Siregar Epi Supriyani , Gulyanto Bambang , Imanuddin Imanuddin , Hariati Puji , Kurniati Rizki 
Published: July 2024

Hasil belajar mahasiswa pada mata kuliah pembelajaran agama Islam pada Program Studi PJKR UPMI Medan akan dinilai dalam penelitian ini dari hasil pemanfaatan media pembelajaran online melalui aplikasi Google Meet. Kelompok mahasiswa yang berpartisipasi dalam pembelajaran melalui Google Meet diberikan data pretest dan posttest sebagai bagian dari desain penelitian eksperimental. Hasil penilaian menunjukkan 1) bahwa peningkatan hasil belajar Mahasiswa berkorelasi signifikan dan positif dengan penggunaan Google Meet. Hasil penelitian ini memiliki implikasi penting dalam pengembangan pendidikan agama berbasis teknologi dan menegaskan potensi penggunaan Google Meet sebagai alat pembelajaran yang efektif. Disarankan untuk terus mengintegrasikan teknologi dalam pembelajaran agama dan melakukan pelatihan lebih lanjut untuk meningkatkan kompetensi dosen dan Mahasiswa dalam menggunakan media pembelajaran online. Penelitian lebih lanjut dapat dilakukan untuk mengidentifikasi faktor-faktor yang memengaruhi efektivitas media pembelajaran online dalam konteks agama.<p> </p>
Trauma cultural y violencia en el México contemporáneo
Authors: Telléz Parra Andrés 
Published: July 2024

El artículo hace una breve revisión de la manera en que el concepto de trauma proveniente del psicoanálisis ha sido retomado por las ciencias sociales bajo el término de trauma social o cultural, así como por los estudios de cine, con el fin de utilizarlo para analizar la manera en que dos eventos traumáticos de la historia mexicana contemporánea, a saber, la matanza de estudiantes en la Plaza de las Tres Culturas de la Ciudad de México el 2 de octubre de 1968 y la desaparición forzada, la noche del 26 de septiembre de 2014, de 43 estudiantes de la Escuela Normal Rural “Raúl Isidro Burgos”, de Ayotzinapa, son reelaborados en la película Los parecidos de Isaac Ezban, en el contexto de la violencia generada por el crimen organizado en la sociedad mexicana contemporánea.
La potencia subversiva del Cuerpo-sin-Órganos. Eraserhead de David Lynch como secuela de Crímenes del futuro de David Cronenberg
Authors: Campillo Luis Ángel 
Published: July 2024

El objetivo del presente escrito es hacer una lectura de la película Crímenes del futuro (2022) de David Cronenberg a partir de la filosofía de Gilles Deleuze y Felix Guattari. Gracias a los conceptos Cuerpo-sin-Órganos, organismo y rostro, comprobaremos que la potencia revolucionaria de la antedicha película queda neutralizada. Así que buscaremos algún otro agente que pueda ejecutar el potencial subversivo planteado por la película de Cronenberg y lo hallaremos en la extraña criatura de Eraserhead (1977) de David Lynch.
Freud y la “intuición cinematográfica”: psicoanálisis, cine y epistemología
Authors: Berton Mireille 
Published: July 2024

Este artículo propone, a partir de una breve evaluación historiográfica, considerar las redes de relaciones entre psicoanálisis y cine según una nueva modalidad que atravesaría estas dos esferas “gemelas” en una perspectiva epistemológica. El planteamiento de la autora consiste en cuestionar la manera en que la teoría psicoanalítica pone en juego algo que se relaciona con el dispositivo cinematográfico. Se trata entonces de involucrar el sintagma “psicoanálisis y cine” en el campo de un estudio más amplio de la episteme de la que forma parte y que implícitamente hace funcionar al cine dentro del propio campo psicoanalítico, al tiempo que lo emancipa, lo libera de su “estado auxiliar”.
Reseña de libro: Un curso sobre los derechos humanos en la gran pantalla
Authors: Pérez Fernández Francisco 
Published: July 2024

Este artículo tiene como objetivo comentar brevemente la obra Los derechos humanos en el cine, escrita por Benjamín Rivaya García. El libro en cuestión es un original ejercicio de análisis sobre la presencia que los derechos humanos han tenido en la narración cinematográfica a lo largo de la historia. Tal y como nos explica su autor, los fines perseguidos por la obra son explicar la particular forma en la que el cine se relaciona con el mundo jurídico, identificar los elementos de corte ideológico que se encuentran presentes en el discurso fílmico y reivindicar el papel indiscutible que el cine tiene a día de hoy como recurso educativo. Su lectura resulta especialmente reveladora a la hora abordar todas estas amplias cuestiones, las cuales no siempre son tratadas conforme a la importancia que sin duda les es propia. Aquí trataremos de realizar una breve exposición y comentario de los temas principales tratados en el libro, con la intención de fomentar un acercamiento diferente y placentero al arte cinematográfico.
Study and Optimization of a New Perovskite Solar Cell Structure Based on the Two Absorber Materials Cs2TiBr6 and MASnBr3 Using SCAPS 1D
Authors: Dris Keltoum , Benhaliliba Mostefa 
Published: July 2024

The main objective of this study is to optimize the photovoltaic parameters of a new perovskite solar cell structure (PSC) suggested, using the simulator solar cell capacitance simulator-one dimension (SCAPS-1D) which aims to improve its performance by adjusting different key variables. This new suggested cell which consists of six materials represents the major innovation point of our research, it is distinguished by a double active layer, composed of the two-cesium titanium hexabromide (Cs2TiBr6) and methylammonium tin tribromide (MASnBr3) perovskites. Using the SCAPS 1D software, the simulation allows to determine the optimal values of the various parameters to maximize the efficiency of the PSC. First, the effect of the thickness and defect densities of both Cs2TiBr6 and MASnBr3 materials on the output parameters was studied as well as the defect density in the interfaces. Subsequently, the doping density in Cs2TiBr6 and MASnBr3 was also optimized. Finally, the impact of temperature, series resistance and shunt resistance were evidenced. The results indicate that precise adjustments of these parameters can lead to significant improvements in photovoltaic performance, such as open circuit voltage of 1.105 V, short-circuit current density of 33.90 mA cm−2, fill factor of 88.01% and power conversion efficiency (PCE) 32.96%. These performances were obtained for a thickness of 700 nm for Cs2TiBr6 and 900 nm for MASnBr3, a defect density of 1014 cm−3 for each absorber layer, a defect density of 1014 cm−2 for each interface and a doping density of the order of 1018 cm−3 for each absorbent layer.
Análisis de la vivienda rural en Cebadas: un enfoque morfológico, constructivo y bioclimático
Authors: Cajamarca Dacto Karina Elizabeth , Montero Riofrio Jean Carlos , Morales González Janeth Alexandra , González Espinosa Maikol Josueé 
Published: July 2024

Introducción: La arquitectura vernácula, arraigada por siglos, refleja la conexión íntima entre comunidades y entorno, empleando recursos locales y respetando condiciones ambientales y culturales. Adaptada al clima y eficiente energéticamente, ofrece confort térmico con materiales naturales y ventilación. A pesar de las amenazas del diseño moderno, conservar esta arquitectura es crucial para evitar riesgos ambientales y sociales, y sostener la identidad comunitaria y sostenibilidad. En Cebadas, Chimborazo, familias enfrentan problemas socioeconómicos e infraestructurales graves, viviendo en viviendas deficientes funcional y bioclimáticamente, muchas abandonadas o demolidas por modificaciones inadecuadas, afectando la identidad local. Objetivo: Realizar un análisis detallado de la vivienda rural de Cebadas en la provincia de Chimborazo mediante un estudio morfológico, constructivo y bioclimático. Metodología: La investigación combina métodos cualitativos y cuantitativos para evaluar viviendas rurales en Cebadas, Chimborazo. Utiliza tanto la exploración bibliográfica como el diagnóstico cuantitativo en el sitio para identificar las viviendas más idóneas para el análisis comparativo. Fundamentada teóricamente en bibliografía, este estudio de tipo documental y de campo examina parámetros clave como técnicas de construcción y materiales empleados. Resultados: En la etapa de diagnóstico del sitio de estudio, se identificaron 16 edificaciones de interés en el sector, seleccionándose 13 para un análisis detallado basado en parámetros de evaluación. Las tres edificaciones nuevas restantes no fueron valoradas para el estudio., ya que son edificaciones de carácter moderno. En donde, se analizaron en detalle las edificaciones E9 y E10 en función de su entorno, visuales, forma, función, bioclimática y materiales. Conclusión: La investigación revela la urgente necesidad de abordar el rescate de identidad arquitectónica y la sostenibilidad en el diseño y la gestión de recursos, asegurando el bienestar a largo plazo de la comunidad. Área de estudio general: Arquitectura Área de estudio específica: Vivienda Rural
Effect of precipitating agent, N2 gas, extract volume and pH on the magnetic properties of magnetite nanoparticles by green synthesis from aqueous pomegranate peel extract
Authors: Dehghani Marzieh , Hajipour-Verdom Behnam , Abdolmaleki Parviz 
Published: July 2024

Superparamagnetic nanoparticles (SPMNPs) have attracted considerable attention in biomedicine, particularly magnetic hyperthermia for cancer treatment. However, the development of efficient and eco-friendly methods for synthesizing SPMNPs remains a challenge. This study reports on a green synthesis approach for SPMNPs using pomegranate peel extract as a stabilizing agent. The effects of various synthesis parameters, including the type of precipitating agent (NH3 and NaOH), N2 gas, extract volume, and pH, were systematically investigated with regard to the size, morphology, and magnetic properties of the nanoparticles. The results showed that reducing the volume of the extract increased the saturation magnetization of the nanoparticles. N2 gas was found to be essential in preventing the oxidation of the nanoparticles. The type of precipitating agent also affected the size and magnetization of the nanoparticles, with NaOH leading to the synthesis of SPMNPs with higher magnetization (∼4 times) compared to NH3. Additionally, nanoparticles synthesized at pH 10 exhibited higher magnetization than those synthesized at pH 8 and 12. In conclusion, the optimized synthesis conditions significantly affected the magnetization and stability of SPMNPs. These nanoparticles are suitable for use in magnetic nanofluid hyperthermia applications.
MnoSR removal in Mycobacterium smegmatis triggers broad transcriptional response to 1,3-propanediol and glucose as sole carbon sources
Authors: Płocińska Renata , Struś Katarzyna , Korycka-Machała Małgorzata , Płociński Przemysław , Kuzioła Magdalena , Żaczek Anna , Słomka Marcin , Dziadek Jarosław 
Published: July 2024

IntroductionThe two-component signal transduction systems play an essential role in the adaptation of bacteria to changing environmental conditions. One of them is the MnoSR system involved in the regulation of methylotrophic metabolism in M. smegmatis.MethodsMycobacterium smegmatis mutant strains ΔmnoS, ΔmnoR and ΔmnoS/R lacking functional mnoS, mnoR and both genes were generated using a homologous recombination approach. MnoR recombinant protein was purified by affinity column chromatography. The present study employs molecular biology techniques: cloning strategies, global RNA sequencing, qRT-PCR, EMSA, Microscale thermophoresis, and bioinformatics analysis.Results and discussionThe ∆mnoS, ∆mnoR, and ∆mnoS/R mutant strains were generated and cultured in the presence of defined carbon sources. Growth curve analysis confirmed that inactivation of the MnoSR impairs the ability of M. smegmatis cells to use alcohols such as 1,3-propanediol and ethanol but improves the bacterial growth on ethylene glycol, xylitol, and glycerol. The total RNA sequencing method was employed to understand the importance of MnoSR in the global responses of mycobacteria to limited carbon access and in carbon-rich conditions. The loss of MnoSR significantly affected carbon utilization in the case of mycobacteria cultured on glucose or 1,3-propanediol as sole carbon sources as it influenced the expression of multiple metabolic pathways. The numerous transcriptional changes could not be linked to the presence of evident MnoR DNA-binding sites within the promotor regions for the genes outside of the mno operon. This was confirmed by EMSA and microscale thermophoresis with mutated MnoR binding consensus region. Our comprehensive analysis highlights the system’s vital role in metabolic adaptability, providing insights into its potential impact on the environmental survival of mycobacteria.
Unveiling mode effects in grade 1 vocabulary assessment: the intriguing influence of test mode
Authors: Seifert Susanne , Paleczek Lisa , Schöfl Martin , Weber Christoph 
Published: July 2024

BackgroundVocabulary knowledge plays a pivotal role in academic development, particularly among Grade 1 students. To support students in their academic development, effective assessment instruments in educational settings are crucial. The GraWo (Graz Vocabulary Test) is introduced as a tool designed to evaluate receptive vocabulary in German-speaking countries in print and in digital mode.ObjectivesThis study aims to investigate mode effects in the GraWo among Grade 1 students, comparing vocabulary gains in digital and print versions. Additionally, it explores the influence of student characteristics, such as gender and language status, and examines item-level differences between the two modes in order to gain a more comprehensive understanding of test performance.DesignThe research design entails a longitudinal approach, following children (n = 421) from the beginning to the end of Grade 1, varying the test modes (digital or print) only at second measurement (40% receiving the print version), while at first measurement all children worked with the digital version.ResultsBaseline comparisons of test mode groups indicated almost no significant differences. In terms of growth in vocabulary during Grade 1, an ANOVA with repeated measures revealed a main effect for time, indicating increased performance in both groups at second measurement. Moreover, an interaction effect between time and test mode group showed that the print group exhibited higher gains in the vocabulary test compared to the digital group. Further analysis using MNLFA confirmed that the print mode group outperformed the digital group overall and that four items were also individually affected by differences between the digital and print versions.ConclusionThe study emphasizes the need for nuanced investigations into the impact of test mode on student performance and suggests incorporating observational methods to comprehensively understand student interactions with digital and print modes. In acknowledging potential variations in performance, educators and policymakers need to tailor practices to accommodate the demands of hybrid test procedures and to consider the role of digital competence in shaping testing experiences.
Lipids, lipid-modified drug target genes, and the risk of male infertility: a Mendelian randomization study
Authors: Li Wei , Li Hu , Zha Cheng , Che Bangwei , Yu Ying , Yang Jianjun , Li Tao 
Published: July 2024

BackgroundPrevious observational studies have reported a possible association between circulating lipids and lipid-lowering drugs and male infertility (MIF), as well as the mediating role of circulating vitamin D. Then, due to issues such as bias, reverse causality, and residual confounding, inferring causal relationships from these studies may be challenging. Therefore, this study aims to explore the effects of circulating lipids and lipid-lowering drugs on MIF through Mendelian randomization (MR) analysis and evaluate the mediating role of vitamin D.MethodGenetic variations related to lipid traits and the lipid-lowering effect of lipid modification targets are extracted from the Global Alliance for Lipid Genetics Genome-Wide Association Study. The summary statistics for MIF are from the FinnGen 9th edition. Using quantitative expression feature loci data from relevant organizations to obtain genetic variations related to gene expression level, further to explore the relationship between these target gene expression levels and MIF risk. Two-step MR analysis is used to explore the mediating role of vitamin D. Multiple sensitivity analysis methods (co-localization analysis, Egger intercept test, Cochrane’s Q test, pleiotropy residuals and outliers (MR-PRESSO), and the leave-one-out method) are used to demonstrate the reliability of our results.ResultIn our study, we observed that lipid modification of four lipid-lowering drug targets was associated with MIF risk, the LDLR activator (equivalent to a 1-SD decrease in LDL-C) (OR=1.94, 95% CI 1.14-3.28, FDR=0.040), LPL activator (equivalent to a 1-SD decrease in TG) (OR=1.86, 95% CI 1.25-2.76, FDR=0.022), and CETP inhibitor (equivalent to a 1-SD increase in HDL-C) (OR=1.28, 95% CI 1.07-1.53, FDR=0.035) were associated with a higher risk of MIF. The HMGCR inhibitor (equivalent to a 1-SD decrease in LDL-C) was associated with a lower risk of MIF (OR=0.38, 95% CI 0.17-0.83, FDR=0.39). Lipid-modifying effects of three targets were partially mediated by serum vitamin D levels. Mediation was 0.035 (LDLR activator), 0.012 (LPL activator), and 0.030 (CETP inhibitor), with mediation ratios of 5.34% (LDLR activator), 1.94% (LPL activator), and 12.2% (CETP inhibitor), respectively. In addition, there was no evidence that lipid properties and lipid modification effects of six other lipid-lowering drug targets were associated with MIF risk. Multiple sensitivity analysis methods revealed insignificant evidence of bias arising from pleiotropy or genetic confounding.ConclusionThis study did not support lipid traits (LDL-C, HDL-C, TG, Apo-A1, and Apo-B) as pathogenic risk factors for MIF. It emphasized that LPL, LDLR, CETP, and HMGCR were promising drug targets for improving male fertility.
Perspectives from cystinosis: access to healthcare may be a confounding factor for variant classification
Authors: Wu Chen-Han Wilfred , Tomaszewski Alicja , Stark Louisa , Scaglia Fernando , Elenberg Ewa , Schumaker Fredrick R. 
Published: July 2024

Genetic variability persists across diverse populations, and it may impact the characterization of heritable diseases in different ancestral groups. Cystinosis is a metabolic disease caused by pathogenic variants in the CTNS gene causing the cellular accumulation of cystine. We attempted to assess the currently poorly characterized prevalence of cystinosis by employing a population genetics methodology. However, we encountered a significant challenge due to genetic variations across different populations, and the consideration of potential disparities in access to healthcare made our results inconclusive. Pathogenic CTNS variants were identified in a representative global population cohort using The Human Gene Mutation Database (HGMD) and the 1000 Genomes (1 KG) database. The c.124G&gt;A (p.Val42Ile) variant was reported to be pathogenic based on an observation in the white population presenting with atypical phenotypes, but it would be reclassified as benign in the African ancestral group if applying the ACMG allele frequency guideline due to its high allele frequency specifically in this population. Inclusion or exclusion of this c.124G&gt;A (p.Val42Ile) variant results in a significant change in estimated disease prevalence, which can impact the diagnosis and treatment of affected patients with a broad range of phenotypic presentations. This observation led us to postulate that pathogenic manifestations of the disease may be underdiagnosed due to variable expressivity and systemic inequities in access to care, specifically in the African subpopulation. We call for a more cautious and inclusive approach to achieve more equitable care across diverse populations.