bluuebunny/crossref_metadata_2025_split huggingface dataset:
Health related quality of life of children with rheumatic heart diseases: reliability of the Brazilian version of the pediatric quality of life inventory™ cardiac module scale
Authors: do Nascimento Moraes Anabela , Ramos Ascensão Terreri Maria Teresa , Esteves Hilário Maria Odete , Len Cláudio Arnaldo 
Published: November 2013

Abstract

Background
This study aimed to translate the ‘Pediatric Quality of Life Inventory™ (PedsQL™ 3.0) Cardiac Module’ into Portuguese, adapt it to Brazilian culture, and assess its psychometric properties (validity and reproducibility), and to calculate health-related quality of life scores on the PedsQL 4.0 and PedsQL™ 3.0 Cardiac Module Scales for a group of patients 5 to 18 years old with rheumatic heart disease.

Methods
The methods suggested by the authors of the original version of the questionnaire included 1) translation by an expert panel; 2) translation back into English and revision by the authors of the original version; 3) pilot study with seven children and parents in each of three age ranges (5 to 7, 8 to 12, and 13 to 18 years old); and 4) assessment of the measurement properties. In this stage, the PedsQL™ 3.0 Cardiac Module and the PedsQL 4.0 Generic Scale were applied to a sample comprising 109 children and adolescents with rheumatic heart disease and their parents or caregivers. The version for parents or caregivers was administered separately on the same day.

Results
The values of Cronbach’s alpha for all scales assessed in the questionnaire (heart problems and treatment [symptoms], problems with perceived physical appearance, treatment anxiety, cognitive problems, and communication problems) varied from 0.6 to 0.8, indicating good internal consistency. Correlation was found between the scores for the Cardiac Module and the Generic Scale (0.36-0.86), demonstrating convergent validity (Spearman’s correlation coefficient, p < 0.01). The symptoms, problems with perceived physical appearance, and cognitive and communication problem domains were able to distinguish between groups of patients with mild and moderate/severe heart disease (Student’s t-test, p < 0.05). The intraclass correlation of the interobserver reproducibility was adequate (0.76 to 0.94 among the patients [children/adolescents] and 0.76 to 0.84 among their caregivers). The correlation between the patients’ scores and their parents’ scores varied from 0.50 to 0.86 (Pearson’s correlation coefficient, p < 0.01).

Conclusions
The Brazilian version of the PedsQL™ 3.0 Cardiac Module was shown to be reliable. The application of this questionnaire in practice will be very useful for all professionals charged with the care of children and adolescents with heart diseases.
Cadherin-12 contributes to tumorigenicity in colorectal cancer by promoting migration, invasion, adhersion and angiogenesis
Authors: Zhao Jingkun , Li Pu , Feng Hao , Wang Puxiongzhi , Zong Yaping , Ma Junjun , Zhang Zhuo , Chen Xuehua , Zheng Minhua , Zhu Zhenggang , Lu Aiguo 
Published: November 2013

Abstract

Background
Cadherin 12 (CDH12), which encodes a type II classical cadherin from the cadherin superfamily, may mediate calcium-dependent cell adhesion. It has been demonstrated that CDH12 could play an important role in the invasion and metastasis of salivary adenoid cystic carcinoma. We decided to investigate the relationship between CDH12 expression level and clinicopathologic variables in colorectal carcinoma (CRC) patients and to explore the functions of CDH12 in tumorigenesis in CRC.

Methods
The expression levels of CDH12 in colorectal carcinoma tissues were detected by immunohistochemistry. Real-time PCR and Western Blot were used to screen CDH12 high-expression cell lines. CCK-8 assay was used to detect the proliferation ability of CRC cells being transfected by shRNAs against CDH12. The wound assay and transwell assay were performed to test migration and invasion ability. The importance of CDH12 in cell-cell junctions was detected by cell adhesion assay and cell aggregation assay. Endothelial tube formation assay was used to test the influence of CDH12 on angiogenesis.

Results
Statistical analysis of clinical cases revealed that the positive rate of CDH12 was higher in the CRC tumor tissues compared with the adjacent non-tumor tissues. The expression levels of CDH12 in CRC patients are significantly correlated with invasion depth. Consistently, the ability of proliferation, migration and invasion were suppressed when CDH12 was decreased in CRC cells transfected with shRNAs. Cell adhesion assay and cell aggregation assay presented that tumor cells tend to disperse with the lack of CDH12. Endothelial tube formation assay showed that down-regulation of CDH12 could obviously inhibit the process of angiogenesis, implying that CDH12 may play an important role in tumor metastasis

Conclusion
Our results showed that CDH12 promotes proliferation, migration, invasion, adhesion and angiogenesis, suggesting that CDH12 may be an oncogene in colorectal cancer. CDH12 is expected to become a new diagnostic and prognostic marker and a novel target of the treatment of colorectal cancer.
Automated analysis of non-mass-enhancing lesions in breast MRI based on morphological, kinetic, and spatio-temporal moments and joint segmentation-motion compensation technique
Authors: Hoffmann Sebastian , Shutler Jamie D , Lobbes Marc , Burgeth Bernhard , Meyer-Bäse Anke 
Published: November 2013

Abstract
Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) represents an established method for the detection and diagnosis of breast lesions. While mass-like enhancing lesions can be easily categorized according to the Breast Imaging Reporting and Data System (BI-RADS) MRI lexicon, a majority of diagnostically challenging lesions, the so called non-mass-like enhancing lesions, remain both qualitatively as well as quantitatively difficult to analyze. Thus, the evaluation of kinetic and/or morphological characteristics of non-masses represents a challenging task for an automated analysis and is of crucial importance for advancing current computer-aided diagnosis (CAD) systems. Compared to the well-characterized mass-enhancing lesions, non-masses have no well-defined and blurred tumor borders and a kinetic behavior that is not easily generalizable and thus discriminative for malignant and benign non-masses. To overcome these difficulties and pave the way for novel CAD systems for non-masses, we will evaluate several kinetic and morphological descriptors separately and a novel technique, the Zernike velocity moments, to capture the joint spatio-temporal behavior of these lesions, and additionally consider the impact of non-rigid motion compensation on a correct diagnosis.
Prevalence and predictors of Cervical Intraepithelial Neoplasia among HIV infected women at Bugando Medical Centre, Mwanza-Tanzania
Authors: Kafuruki Lilian , Rambau Peter Fabian , Massinde Anthony , Masalu Nestory 
Published: November 2013

Abstract

Introduction
Cancer of the cervix rank the second most common cause of cancer related deaths among women in Sub-Saharan Africa. It is estimated that 529, 409 new cases are diagnosed annually with a mortality rate approaching 274,883 per year. Cervical Intraepithelial Neoplasia (CIN) precedes almost all cervical cancers. The incidence rate of CIN among HIV infected women is five times higher as compared to the rate in HIV negative women. The screening for cervical dysplasia and an appropriate management in women with CIN are effective methods for preventing cervical cancer. This study was done to determine the prevalence and predictors of CIN among a HIV infected women attending Care and Treatment centre (CTC) at Bugando Medical Centre (BMC).

Methods
A cross sectional survey was undertaken among HIV infected women aged 18 years and above attending at BMC CTC clinic between February and March 2013. Visual Inspection with Acetic acid (VIA) was used as the screening method for detection of CIN. Socio-demographic, reproductive and clinical information was obtained from participants and the blood was collected for CD4 lymphocyte count. Cervical punch biopsy for histological examination was performed for those who had VIA positive test. Data were entered and analyzed using STATA Version 12.0 soft ware.

Results
A total number of 95 (26.8%) participants had positive VIA test among three hundred and fifty-five (355) HIV infected women. Histology results showed; 4(4.2%) were normal, 26 (27.4%) had an inflammatory lesion, 58(61.1%) had CIN and 7(7.3%) had invasive cervical cancer. CIN was found to be associated with a history of multiple sexual partners (P<0.001), a history of genital warts (P<0.001), and a history of STI (P = 0.010).

Conclusion
The Cervical Intraepithelial Neoplasia is a problem among HIV infected women. A history of multiple sexual partners, a history of genital warts, a history STI and a low baseline CD4 T lymphocyte were significant predictors for CIN. Screening for Cervical Intraepithelial Neoplasia is recommended for all women with HIV.
Successful nasal intubation with a laryngeal nerve monitoring tube using bronchoscopy in a patient with plunging goiter: a case report
Authors: Spadaro Savino , D’Agata Manuela , Verri Marco , Ragazzi Riccardo , Volta Carlo A 
Published: November 2013

Abstract

Background
The appropriate positioning of nerve integrity monitoring during thyroid surgery is of relevance. In this case report we describe our experience with accurate placement of a nerve integrity monitoring endotracheal tube, obtained by fiberoptic control, in a patient with expected difficult airway management.

Case presentation
We report the case of a 70-year-old obese woman scheduled for elective total thyroidectomy due to plunging intrathoracic goiter. The preoperative indirect laryngoscopy pointed out a massive bombè of the hypopharyngeal wall to the right and right vocal cord paralysis. The epiglottis was oedematous and the glottis could not be identified. On physical examination, the tongue was large and a Mallampati’s score of 3 was determined. Hence, due to an expected difficult airway management, a nasal intubation with an electromyographic nerve integrity monitoring endotracheal tube trough fiberoptic bronchoscopy was successfully performed.

Conclusion
Our experience suggests that nasal intubation can be safely performed by using a nerve integrity monitoring tube with the help of fiberoptic bronchoscopy.
Locomotor performance of three sympatric species of sea kraits (Laticauda spp.) from Orchid Island, Taiwan
Authors: Wang Shiuang , Lillywhite Harvey B , Tu Ming-Chung 
Published: November 2013

Abstract

Background
Assuming that locomotion has a strong influence on animals’ fitness, we hypothesized that better locomotor performance would be associated with the most frequently utilized habitat. Laticauda colubrina, Laticauda laticaudata, and Laticauda semifasciata have different amphibious habits and microhabitat preferences at Orchid Island, Taiwan. We investigated the morphology and locomotor performance of the three sympatric species of sea krait. The measurements of body size, tail area, and body shape were compared in our study. Data on crawling and swimming speeds were gathered to investigate locomotor performance in terrestrial and aquatic environments.

Results
We found significant differences in the locomotor performances among the three species. L. colubrina was the most terrestrial species in habits and sprinted significantly faster than the others during terrestrial locomotion. On the other hand, L. semifasciata was the most aquatic species, and it swam significantly faster than the other two species. These results are consistent with our hypothesis that sea kraits move well in their respective primary environments. With respect to the highly aquatic L. semifasciata, its laterally compressed body form, large body size, and large area of compressed tail are considered to be beneficial to swimming in an aquatic environment.

Conclusions
More data are required to understand the superior terrestrial locomotion of L. colubrina, but this species may benefit from its more-cylindrical body form compared to L. semifasciata and from its greater muscle mass compared to L. laticaudata. L. laticaudata was intermediate in habits but exhibited the poorest performance in both swimming and terrestrial locomotion. The reasons for this remain unclear.
Optical characteristics and photothermal conversion of natural iron oxide colloid
Authors: Kang Tae Yeon , Chang Ki Soo , Kim Jae Young , Choi Seon-Kang , Chae Weon-Sik 
Published: November 2013

Abstract

Background
Chemical compositions and spectroscopic characteristics of the natural floating colloids in brine mineral water were investigated in this study.

Methods
The natural colloidal materials were investigated using electron microscopy, X-ray crystallography, elemental analysis, and absorption and emission spectroscopies.

Results
The natural colloidal particles have a spherical shape, with average diameter of 200 nm, and amorphous crystalline structure. The colloids are mostly composed of iron and oxygen atoms; they also contained small amounts of trace elements and rare earth minerals. In particular, the colloids show remarkable absorption and emission characteristics in the wide spectral region from ultraviolet (UV) to near infrared (NIR), which could make it useful in photoconversion and hyperthermal applications.

Conclusion
From the photothermal conversion efficiency measurement using an infrared thermography under irradiation of visible and NIR light, interestingly, it was found that the natural colloids have higher photothermal conversion efficiency, as compared with those of several different-typed minerals.
Imaging ER-to-Golgi transport: towards a systems view
Authors: Verissimo Fatima , Pepperkok Rainer 
Published: November 2013

SummaryProteins synthesised at the endoplasmic reticulum (ER) have to undergo a number of consecutive and coordinated steps to reach the Golgi complex. To understand the dynamic complexity of ER-to-Golgi transport at the structural and molecular level, light microscopy approaches are fundamental tools that allow in vivo observations of protein dynamics and interactions of fluorescent proteins in living cells. Imaging protein and organelle dynamics close to the ultra-structural level became possible by combining light microscopy with electron microscopy analyses or super-resolution light microscopy methods. Besides, increasing evidence suggests that the early secretory pathway is tightly connected to other cellular processes, such as signal transduction, and quantitative information at the systems level is fundamental to achieve a comprehensive molecular understanding of these connections. High-throughput microscopy in fixed and living cells in combination with systematic perturbation of gene expression by, e.g. RNA interference, will open new avenues to gain such an understanding of the early secretory pathway at the systems level. In this Commentary, we first outline examples that revealed the dynamic organisation of ER-to-Golgi transport in living cells. Next, we discuss the use of advanced imaging methods in studying ER-to-Golgi transport and, finally, delineate the efforts in understanding ER-to-Golgi transport at the systems level.
The semantic war: The pen as sword in rewriting western representations of Haiti in the media
Authors: Collins Holly L. 
Published: November 2013

Abstract
‘Haiti, a cursed land’ – This headline atop a 2010 French news publication echoes a widely felt and often repeated sentiment about the island of Haiti. In a world where History is written by the victors, the voices of those who, either themselves or whose ancestors were violently oppressed and exploited, often go unheard. Most of the international media is run and disseminated by the majority voice. It is in this way that stereotypes are circulated, myths perpetuated and the parameters that frame and define certain discourses are made to seem natural rather than constructed by those who do the writing. This article examines Dany Laferrière’s engagement in what he calls ‘The Semantic War’ in order to take on the western media and to rewrite the international press’ reductive depiction of Haiti and its people. Laferrière’s first-person account of the events of 12 January 2010 provides a stark contrast to the proliferated view of Haiti as a ‘cursed’ land of poverty and violence. Because of the respect and popularity Laferrière has garnered in the North American literary community, he is able to be a voice for those who are ignored, and combat western-media representations of Haiti from within.
‘Haïti, un peuple maudit’ – Ce gros titre à la une d’une publication française rappelle un sentiment largement ressenti et souvent répété de l’état insulaire Haïti. Dans un monde où l’Histoire s’écrit par les vainqueurs, les voix de ceux qui sont violemment opprimés ou exploités sont trop souvent ignorées. La voix majoritaire dirige et diffuse la plupart de la presse internationale. C’est ainsi que les stéréotypes se font circuler, les mythes sont perpétués, et les paramètres qui encadrent et définissent des discours deviennent vus comme naturels au lieu de construits par ceux qui les écrivent dans l’imaginaire publique. Cet article montre la manière dans laquelle Dany Laferrière s’engage dans ce qu’il appelle ‘la Guerre Sémantique’ afin de confronter la presse occidentale et récrire leur représentation réductrice d’Haïti et son peuple. Le récit à la première personne de Laferrière des événements du 12 janvier 2010 fournit un contraste extrême à l’opinion proliférée d’Haïti comme un pays maudit, pauvre, et violent. Grâce au respect et à la renommée que Laferrière a gagnés dans l’institution littéraire en Amérique du Nord, il est devenu la voix pour ceux qui sont ignorés et combat ainsi les représentations d’Haïti disséminées par les médias occidentaux du dedans.
Book Reviews
Authors: Baker Charlotte , Bromilow Pollie , Frith Nicki , Kosniowski Jenny , Majumdar Margaret A. , McIlvanney Siobhán , Tarica Estelle , Thomas Bonnie , Yaacoub Faten , Zayzafoon Lamia 
Published: November 2013

Abstract
La Création Romanesque chez Williams Sassine, Philip Amangoua Atcha (2011) Paris: Harmattan, 252 pp., ISBN: 978-2-296-55053-7, p/bk, 23.50
A Taste for the Foreign: Worldly Knowledge and Literary Pleasure in Early Modern French Fiction, Ellen R. Welch (2011) Newark: University of Delaware Press, xxviii + 225pp., ISBN: 978-1-61149-062-6, h/bk, £44.95
Violence in Francophone African & Caribbean Women’s Literature, Chantal Kalisa (2009) Lincoln, NE: University of Nebraska Press, 225 pp., ISBN: 978-0-8032-1102-5, h/bk, $45.00
Writing Postcolonial France: Haunting, Literature, and the Maghreb, Fiona Barclay (2011) Plymouth: Lexington Books, 152 pp, ISBN: 978-0-7391-4503-6, h/bk, $64.99, £39.95
La Terre et le sang/Land and Blood (trans. Patricia Geesey), Mouloud Feraoun ([1953]) 2012) Charlottesville/London: University of Virginia Press, 243 pp., ISBN: 978-0-8139-3220-0, h/bk, $59.50; ISBN: 978-0-8139-3221-7, p/bk, $22.50
Cherchez la femme: Women and Values in the Francophone World, Erika Fülöp and Adrienne Angelo (eds) (2011) Newcastle upon Tyne: Cambridge Scholars Publishing, 292 pp., ISBN: 978-1-4438-2933-5, h/bk, £39.99
Patrick Chamoiseau: A Critical Introduction, Wendy Knepper (2012) Jackson: University Press of Mississippi, 274pp., ISBN: 978-1-61703-154-0, h/bk, ebook 978-1-61703-155-7, $55
Beyond the Slave Narrative: Politics, Sex, and Manuscripts in the Haitian Revolution, Deborah Jenson (2011) Liverpool: Liverpool University Press, 322 pp., ISBN: 978-1-84631-497-1, h/bk, £65, ISBN: 978-1-84631-760-6, p/bk, £16.99
Postcolonial Poetics: Genre and Form, P. Crowley and J. Hiddleston (2011) Liverpool: Liverpool University Press, 279 pp., ISBN: 978-1-84631-745-3, h/bk £55.85
Francophone Women: Between Visibility and Invisibility, Cybelle H. McFadden and Sandrine F. Teixidor (eds) (2010) New York: Peter Lang, Francophone Cultures and Literatures, 143 pp., ISBN: 978-1-4331-0803-7, h/bk, 60 , £48
Corrosion rate of carbon steel under synergistic effect of seawater parameters including pH, temperature, and salinity in turbulent condition
Authors: Toloei Alisina , Atashin Sanam , Pakshir Mahmood 
Published: November 2013

AbstractThe variation of AISI 1045 carbon steel corrosion rate in seawater is investigated under the simultaneous effect of marine parameters in both stagnant and turbulent conditions. The combined effect of salinity, velocity, pH, and temperature is studied using two-by-two graphical curves, while each parameter is applied at three levels. The possible influence of simultaneously acting factors on each considering parameter is experimentally studied and explained using theoretical basis. This paper offers an advantage of considering the simultaneous effect of parameters instead of individual ones, which simulate the experimental media close to the real in-site marine environment where all the affecting factors act in a combined manner. The most innovation of this study is two-by-two investigation of combined action of effective parameters on corrosion rate, which is much more comprehensive and detailed compared to previous researches. Every parameter is considered at three ranges and all the possible interactions with other factors are taken into account. It is proven that the effect of considered parameters on the rate of corrosion is the function of other simultaneously acting factors. The role of fluid velocity condition and also the reaction polarization status is found to be pronounced.
Volga-Volga
Authors: Kupfer Peter 
Published: November 2013

Volga-Volga (1938), the third musical comedy made by the Soviet director-composer team of Grigory Aleksandrov and Isaak Dunayevsky, is one of the most emblematic films of the Soviet 1930s. Indeed, it won its makers a Stalin Prize in 1941 and was supposedly Stalin’s favorite film. But Volga-Volga was also a success with Soviet viewers: they flocked by the millions to see the film, which was still playing in theaters at the outbreak of war in June 1941. As a combination of slapstick comedy and memorable musical numbers that addressed an appropriately Soviet theme, the film clearly spoke to both the masses and officials. But what does Volga-Volga have to say? The film tells the story of a musical “civil war” between a folk ensemble and a classical orchestra, both of which head to Moscow to participate in the national musical Olympiad. Due to “accidental” circumstances, the two ensembles eventually join forces and win the competition with a performance of the “Song about the Volga.”
Though this merger of musical forces and styles seems to serve predominantly comedic purposes, the “story of a song” can also be read as a commentary on the development of music in the Soviet Union in the 1930s. In a period marked by debates and uncertainties in all realms of musical production about what exactly Socialist Realist music was to be, Aleksandrov and Dunayevsky offer as their solution a musical practice that advocates inclusivity by seeking to combine features from many types of music into a distinctly Soviet blend. This thematization of music is enhanced by the nature of the film musical, whose stylistic reliance on music as a bridge between real and ideal worlds embodies the aesthetic demands of Socialist Realism. Furthermore, the film can be understood as an instance of what film scholar Miriam Hansen calls “vernacular modernism,” namely, the adaptation of an American cinematic model into a foreign context as a tool for reflecting and refracting experiences of modernity.