bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development of Generalized Platforms for the Analysis of Complex Datasets
Authors: Gomes Véronique M. , Pereira Ana C. , Saraiva Pedro M. , Reis Marco S. 
Published: February 2014

A systematization of complex data structures, originated in current processes and product analysis activities, is presented as a starting point for developing generalized and flexible frameworks for handling such challenging information sources. In this article, we present an abstract and unifying definition for a class of multidimensional data arrays (here called profiles), built upon which a taxonomy is proposed for their classification, according to aspects relevant for the development of software platforms, namely, the underlying data structure characteristics and the nature of information they convey. Such taxonomy is based on an extensive bibliographic review involving the analysis of complex datasets. Then, we identify the classes of profiles with higher demand (dominant classes) and, for these, conduct a comparison study involving those methodologies that could be applied in the context of two tasks: calibration/regression and process monitoring. The comparison study showed that the Tucker3 and N‐way Partial Least Squares methods are good candidates to incorporate a computational framework addressing the dominant classes of profiles that were identified.The purpose of this ongoing work is to provide fundamental information for developing new software tools able to handle a broad scope of problems, involving the type of complex datasets found in practice, as well as on how to modularly add features regarding the treatment of other, less frequent, classes, to add value to users with more specific interests. Copyright © 2012 John Wiley & Sons, Ltd.
SIRT6 Regulates Osteogenic Differentiation of Rat Bone Marrow Mesenchymal Stem Cells Partially via Suppressing the Nuclear Factor-κB Signaling Pathway
Authors: Sun Hualing , Wu Yanru , Fu Dongjie , Liu Yinchen , Huang Cui 
Published: February 2014

Abstract
Sirtuin 6 (SIRT6) is a NAD-dependent deacetylase involved in lifespan regulation. To evaluate the effect of SIRT6 on osteogenesis, rat bone marrow mesenchymal stem cells (rBMSCs) with enhanced or reduced SIRT6 function were developed. We observed that SIRT6 knockdown significantly reduced the mRNA levels of several key osteogenic markers in vitro, including alkaline phosphatase (ALP), Runt-related transcription factor 2 (RUNX2), and osteocalcin, while overexpression of SIRT6 enhanced their expression. Additionally, SIRT6 knockdown activated nuclear factor-κB (NF-κB) transcriptional activity and upregulated the expression of acetyl-NF-κB p65 (Lys310). The decreased osteogenic differentiation ability of rBMSCs could be partially rescued by the addition of NF-κB inhibitor BAY 11–7082. Furthermore, SIRT6 overexpression in rBMSCs combined with the use of collagen/chitosan/hydroxyapatite scaffold could significantly boost new bone formation in rat cranial critical-sized defects, as determined by microcomputed tomography and histological examination. These data confirm that SIRT6 is mainly located in the nuclei of rBMSCs and plays an essential role in their normal osteogenic differentiation, partly by suppressing NF-κB signaling. Stem Cells 2014;32:1943–1955
EM channel characteristics and their impact on MAC layer performance in underwater surveillance networks
Authors: Li Jun , Toulgoat Mylène 
Published: February 2014

AbstractWireless communications and multihop networking based on electromagnetic (EM) radios have been considered as an alternative to acoustic communications in seawater because in typical applications for networked underwater sensing, EM waves are much less susceptible to multipath distortion and environmental noise. In this paper, we discuss the characteristics of EM channels in seawater and derive a novel EM signal propagation model. Based on the propagation model, we implement in the QualNet network simulator an EM underwater surveillance network for studying the impact of these unique characteristics of underwater EM channels on the media access control (MAC) layer performance. Both a single‐hop network model and a multihop network model are simulated. Simulation results show that the carrier sense multiple access without or with acknowledgement (CSMAWithoutACK or CSMAWithACK, respectively) has advantages over ALOHA and multiple access with collision avoidance in terms of packet average delay, packet delivery ratio, and MAC scheme overhead. In the multihop network model, the use of CSMAWithoutACK significantly reduces the packet average delay and the MAC scheme overhead, and both CSMAWithoutACK and CSMAWithACK achieve more than 90% packet delivery ratio. Therefore, CSMAWithoutACK (with no handshaking via request‐to‐send and clear‐to‐send control packets) is the most appropriate MAC protocol to be used in multihop EM‐based underwater surveillance networks. © Her Majesty the Queen in Right of Canada 2014. Reproduced with the permission of the Minister of Industry Canada
Maximum power‐point tracking control for wind farms
Authors: Gebraad P. M. O. , van Wingerden J. W. 
Published: February 2014

AbstractThis paper presents a data‐driven adaptive scheme to adjust the control settings of each wind turbine in a wind farm such that an increase in the total power production of the wind farm is achieved. This is carried out by taking into account the interaction between the turbines through wake effects. The optimization scheme is designed in such a way that it yields fast convergence so that it can adapt to changing wind conditions quickly. The scheme has a distributed architecture in which each wind turbine adapts its control settings through gradient‐based optimization, using information that it receives from neighbouring turbines. The novel control method is tested in a simulation of the Princess Amalia Wind Park. It is shown that the distributed gradient‐based approach performs the optimization in a more time‐efficient manner compared with an existing data‐driven wind farm power optimization method that uses a game theoretic approach. Copyright © 2014 John Wiley & Sons, Ltd.
Enculturation and Attitudes Toward Intimate Partner Violence and Gender Roles in an Asian Indian Population: Implications for Community‐Based Prevention
Authors: Yoshihama Mieko , Blazevski Juliane , Bybee Deborah 
Published: February 2014

AbstractThis study examined the relationships among enculturation, attitudes supporting intimate partner violence (IPV‐supporting attitudes), and gender role attitudes among one of the largest Asian Indian population groups in the US. Data were collected via computer‐assisted telephone interviews with a random sample of Gujarati men and women aged 18–64 in Metropolitan Detroit. Using structural equation modeling, we modeled the effects of three components of enculturation (behavior, values, and community participation) on gender role attitudes and IPV‐supporting attitudes among married respondents (N = 373). Analyses also accounted for the effects of respondent age, education, religious service attendance, perceived financial difficulty, and lengths of residence in the US. The second‐order, overall construct of enculturation was the strongest predictor of IPV‐supporting attitudes (standardized B = 0.61), but not gender role attitudes. Patriarchal gender role attitudes were positively associated with IPV‐supporting attitudes (B = 0.49). In addition to the overall effect of the enculturation construct, two of the components of enculturation had specific effects. “Enculturation‐values” had a specific positive indirect association with IPV‐supporting attitudes, through its relationship with patriarchal gender role attitudes. However, “enculturation‐community participation” was negatively associated with IPV‐supporting attitudes, suggesting the importance of community‐based prevention of IPV among this immigrant population group.
MOCK THETA FUNCTIONS AND QUANTUM MODULAR FORMS
Authors: FOLSOM AMANDA , ONO KEN , RHOADES ROBERT C. 
Published: February 2014

AbstractRamanujan’s last letter to Hardy concerns the asymptotic properties of modular forms and his ‘mock theta functions’. For the mock theta function $f(q)$, Ramanujan claims that as $q$ approaches an even-order $2k$ root of unity, we have $$\begin{eqnarray*}f(q)- (- 1)^{k} (1- q)(1- {q}^{3} )(1- {q}^{5} )\cdots (1- 2q+ 2{q}^{4} - \cdots )= O(1).\end{eqnarray*}$$ We prove Ramanujan’s claim as a special case of a more general result. The implied constants in Ramanujan’s claim are not mysterious. They arise in Zagier’s theory of ‘quantum modular forms’. We provide explicit closed expressions for these ‘radial limits’ as values of a ‘quantum’ $q$-hypergeometric function which underlies a new relationship between Dyson’s rank mock theta function and the Andrews–Garvan crank modular form. Along these lines, we show that the Rogers–Fine false $\vartheta $-functions, functions which have not been well understood within the theory of modular forms, specialize to quantum modular forms.
Casein improves brachial and central aortic diastolic blood pressure in overweight adolescents: a randomised, controlled trial
Authors: Arnberg Karina , Larnkjær Anni , Michaelsen Kim F. , Jensen Signe Marie , Hoppe Camilla , Mølgaard Christian 
Published: February 2014

AbstractArterial stiffness, blood pressure (BP) and blood lipids may be improved by milk in adults and the effects may be mediated via proteins. However, limited is known about the effects of milk proteins on central aortic BP and no studies have examined the effects in children. Therefore, the present trial examined the effect of milk and milk proteins on brachial and central aortic BP, blood lipids, inflammation and arterial stiffness in overweight adolescents. A randomised controlled trial was conducted in 193 overweight adolescents aged 12–15 years. They were randomly assigned to drink 1 litre of water, skimmed milk, whey or casein for 12 weeks. The milk-based test drinks contained 35 g protein/l. The effects were compared with the water group and a pretest control group consisting of thirty-two of the adolescents followed 12 weeks before the start of the intervention. Outcomes were brachial and central aortic BP, pulse wave velocity and augmentation index, serum C-reactive protein and blood lipids. Brachial and central aortic diastolic BP (DBP) decreased by 2·7% (P = 0·036) and 2·6 % (P = 0·048), respectively, within the casein group and the changes were significantly different from those of the pretest control group (P = 0·040 and P = 0·034, respectively). There was a significant increase in central aortic DBP, and in brachial and central systolic BP in the whey group compared with the water group (P = 0·003, P = 0·009 and P = 0·002, respectively). There were no changes in measures of arterial stiffness or blood lipid concentrations. A high intake of casein improves DBP in overweight adolescents. Thus, casein may be beneficial for younger overweight subjects in terms of reducing the long-term risk of CVD. In contrast, whey protein seems to increase BP compared with drinking water; however, water may be considered an active control group.
Iron deficiency, cognition, mental health and fatigue in women of childbearing age: a systematic review
Authors: Greig Alecia J. , Patterson Amanda J. , Collins Clare E. , Chalmers Kerry A. 
Published: February 2014

AbstractIt is known that Fe deficiency has a negative impact on cognitive function in children by altering brain energy metabolism and neurotransmitter function. It is unclear whether Fe deficiency has detrimental effects on cognition, mental health and fatigue in women of childbearing age. Our aim was to systematically review the literature to determine whether Fe deficiency in women of childbearing age affects cognition, mental health and fatigue, and whether a change in Fe status results in improvements in cognition, mental health and fatigue. Studies using Fe supplement interventions were reviewed to examine the effect of Fe deficiency in women of childbearing age (13–45 years) on their cognition, mental health and fatigue. English-language articles ranging from the earliest record to the year 2011 were sourced. The quality of retrieved articles was assessed and the Fe pathology, cognitive, mental health and fatigue data were extracted. Means and standard deviations from cognitive test data were included in meta-analyses of combined effects. Of the 1348 studies identified, ten were included in the review. Three studies showed poorer cognition and mental health scores and increased fatigue with Fe deficiency at baseline. Seven studies reported an improvement in cognitive test scores after Fe treatment. Results of three of these studies were included in meta-analyses of the effect of Fe supplement intervention on cognition. The results of the meta-analyses showed a significant improvement in Arithmetic scores after treatment (P < 0·01), but no effect on Digit Symbol, Digit Span or Block Design. While an improvement in cognition after Fe treatment was seen in seven out of ten studies, the evidence base is limited by poor study quality and heterogeneity across studies. Additional high-quality studies using consistent measures are warranted.
Individual differences in the scope of speech planning: evidence from eye-movements
Authors: SWETS BENJAMIN , JACOVINA MATTHEW E. , GERRIG RICHARD J. 
Published: February 2014

abstractPrevious research has demonstrated that the scope of speakers’ planning in language production varies in response to external forces such as time pressure. This susceptibility to external pressures indicates a flexibly incremental production system: speakers plan utterances piece by piece, but external pressures affect the size of the pieces speakers buffer. In the current study, we exploreinternalconstraints on speech planning. Specifically, we examine whether individual differences in working memory predict the scope and efficiency of advance planning. In our task, speakers described picture arrays to partners in a matching game. The arrays sometimes required speakers to note a contrast between a sentence-initial object (e.g., a four-legged cat) and a sentence-final object (e.g., a three-legged cat). Based on prior screening, we selected participants who differed on verbal working memory span. Eye-movement measures revealed that high-span speakers were more likely to gaze at the contrasting pictures prior to articulation than were low-span speakers. As a result, high-span speakers were also more likely to reference the contrast early in speech. We conclude that working memory plays a substantial role in the flexibility of incremental speech planning.
Effects of consumption of main and side dishes with white rice on postprandial glucose, insulin, glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 responses in healthy Japanese men
Authors: Kameyama Noriko , Maruyama Chizuko , Matsui Sadako , Araki Risa , Yamada Yuichiro , Maruyama Taro 
Published: February 2014

The co-ingestion of protein, fat and fibre with carbohydrate reportedly affects postprandial glucose, insulin and incretin (glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1)) responses. However, the effects of combination dishes with carbohydrate-rich foods at typically eaten amounts remain unclear. The objective of the present study was to evaluate the effects of consuming recommended amounts of side dishes with boiled white rice in the same meal on postprandial plasma glucose, insulin and incretin hormone responses. A total of nine healthy male volunteers consumed four different meals in a random order on separate days. The test meals were as follows: S, white rice; SM, addition of protein-rich main dishes to the S meal; SMF, addition of a fat-rich food item to the SM meal; SMFV, addition of vegetables to the SMF meal. Plasma glucose, GIP and GLP-1 and serum insulin concentrations were determined during a 3 h period after consumption of these meals. Postprandial glucose responses were lower after SMFV meal consumption than after consumption of the other meals. The incremental AUC for GIP (0–180 min) were largest after consumption of the SMF and SMFV meals, followed by that after SM meal consumption, and was smallest after S meal consumption (P< 0·05). Furthermore, we found GIP concentrations to be dose dependently increased by the fat content of meals of ordinary size, despite the amount of additional fat being small. In conclusion, the combination of recommended amounts of main and vegetable side dishes with boiled white rice is beneficial for lowering postprandial glucose concentrations, with an increased incretin response, when compared with white rice alone.
Metabolic profile before and after short-term overfeeding with a high-fat diet: a comparison between South Asian and white men
Authors: Wulan Siti N. , Westerterp Klaas R. , Plasqui Guy 
Published: February 2014

For the same BMI, South Asians have a higher body fat percentage and an adverse metabolic profile compared with whites. The objective of the present study was to determine the metabolic profiles of South Asian and white men matched for body fat percentage in response to short-term overfeeding with a high-fat diet. A total of ten healthy non-diabetic South Asian men matched for body fat percentage with ten white men were included in the study. A weight-maintenance diet (containing 30 % fat, 55 % carbohydrate and 15 % protein) was provided for 3 d followed by 4 d of overfeeding (150 % of energy requirement) with a high-fat diet (60 % fat, 25 % carbohydrate and 15 % protein). Before and after the overfeeding period, plasma glucose, insulin, TAG, NEFA, total cholesterol and HDL-cholesterol concentrations were determined. Glucose clearance was calculated using a 2 h oral glucose tolerance test. The results revealed that in South Asian and white men, respectively, overfeeding with a high-fat diet decreased plasma TAG concentrations by 0·4 (sd0·6) and 0·4 (sd0·5) mmol/l (Pdiet= 0·008;Pethnicity= 0·24), increased HDL-cholesterol concentrations by 0·12 (sd0·1) and 0·14 (sd0·2) mmol/l (Pdiet= 0·001;Pethnicity= 0·06) and decreased glucose clearance by 48·8 (sd53·5) and 37·2 (sd34·2) ml/min per m2body surface (Pdiet= 0·004;Pethnicity= 0·18). There was a significant interaction between diet and ethnicity with regard to the changes in total and LDL-cholesterol concentrations (P= 0·01 and 0·007, respectively), which trended towards a larger increase in South Asian subjects than in white subjects. Despite a similar body fat percentage, short-term overfeeding with a high-fat diet had more adverse effects on the lipid profile of South Asians than on that of whites.
Cost–utility analysis and otolaryngology
Authors: Hamilton D , Hulme C , Flood L , Powell S 
Published: February 2014

AbstractAs providers of health care, we face increasing demand on our limited, indeed diminishing, resources. Economic appraisal of our interventions means assessing the trade-off between effectiveness, efficiency and equity. When rationing becomes inevitable, calculation of utility values is a valuable decision-making tool. This paper reviews objective measures of patient benefit, such as quality of life, and focuses on their application within otolaryngology.
Red deer exclusion and saxicolous cryptogam community structure
Authors: MOORE Oliver , CRAWLEY Michael J. 
Published: February 2014

AbstractDeer exclosure is an important management strategy for encouraging woodland regeneration in the presence of high numbers ofCervus elaphusL. This could pose a threat to important saxicolous lichen communities as a result of competition from bryophytes and other vegetation. This investigation compared the bryophyte and lichen communities associated with siliceous rock outcrops and boulders inside and outside a number of exclosures in wet heath vegetation at the Gruinard, Letterewe and Little Gruinard estates in Wester Ross. Species cover data were recorded from 6600·2×0·2 m quadrats, allocated to three different aspects of rocks, from 22 pairs of plots (placed either side of a deer fence) with randomization at each level of this hierarchy. The data were analyzed using linear mixed effects models. Mean lichen cover, diversity and species richness were significantly lower in quadrats on rocks within the exclosures. Mean bryophyte cover was significantly higher in quadrats on rocks inside the deer fence and was shown to have a highly significant negative relationship with total lichen cover. Saxicolous lichen species are particularly affected by the increase in shading and litter accumulation from the surrounding plants and the subsequent growth of bryophytes and heath vegetation on rocks within the exclosures. The results of this study have implications for the use of exclosures at locations where there are important saxicolous lichen communities.
Finance and the Northern Expedition: From the Northeast Asian Perspective, 1925–1928
Authors: MAN KWONG CHI 
Published: February 2014

AbstractThis paper looks at the problems faced by the Chinese silver-backed currencies in Manchuria during the period of Northern Expedition (1925–1928), the Chinese attempt to overcome these problems, and the reasons for its failure. Manchuria was a peculiar territory during the interwar period (1919–1939), where several currencies, backed by silver or gold, competed against one another. The Chinese silver banknote, first introduced at the turn of the twentieth century, was challenged by gold-backed Japanese yen issued by the Bank of Korea, and by the Russian ruble. This competition was set in the context of the struggle for political control over the area between China (the Qing Dynasty and its successor, the Chinese Republic), Russia (and its successor the Soviet Union), and the Japanese Empire, as well as the war between the southern Nationalists (Kuomintang) and the militarists (warlords) who controlled the Chinese central government in Beijing and Manchuria. This paper suggests that the difficult financial situation determined the course followed by the warlords, and that their failure was the result of the complex regional context, and the failures in their military strategy rather than of their fiscal policy.
Fading out of view: the enigmatic decline of Rose's mountain toadCapensibufo rosei
Authors: Cressey E. R. , Measey G. J. , Tolley K. A. 
Published: February 2014

AbstractRose's mountain toadCapensibufo roseisurvives in a few isolated montane populations in the south-western Cape of South Africa. It comprises several cryptic species but it is uncertain whether the lineage on the Cape Peninsula is distinct. We tested the hypothesis that toads from the Peninsula form a single genetic lineage but that different breeding sites are divergent at a population level as a result of limited dispersal abilities. Directed surveys were carried out to locate breeding sites and samples obtained were analysed in a phylogenetic and population genetic framework, using two mitochondrial markers. We found toads breeding at only one of five known historical breeding sites, although one new breeding site was also recorded. No toads were observed at 15 other non-breeding localities where they were historically observed. Toads from the two active breeding sites formed a single lineage that was sufficiently distinct to be given species status. However, these were discrete at a population level, with no shared haplotypes, suggesting no gene flow between sites. One site was particularly low in genetic diversity, implying increased vulnerability to stochastic events and elevated risk of extinction. These results, coupled with the failure to locate historically known sites on the Cape Peninsula, make this newly recognized Peninsula endemic a conservation priority. Efforts should focus on the protection and expansion of the two known surviving populations and the patches of habitat upon which they rely.