bluuebunny/crossref_metadata_2025_split huggingface dataset:
Underlying heart disease and microbiological spectrum of adult infective endocarditis in one Chinese university hospital: a 10‐year retrospective study
Authors: Ma X. Z. , Li X. Y. , Que C. L. , Lv Y. 
Published: July 2013

AbstractBackground and AimTo identify the underlying heart disease and microbiological pathogen associated with infective endocarditis (IE) in Chinese patients in one university hospital over a 10‐year period.MethodsWe recruited 115 adult patients admitted to Peking University First Hospital from 2002 to 2011 who were diagnosed with definite IE. Statistical analysis was performed to analyse data on demographics, clinical and laboratory findings, as well as microbiological pathogens.ResultsThe most common underlying heart diseases for IE were congenital heart disease (24.3%) followed by degenerative valvular disease (17.4%). Aortic (44.3%) and mitral (43.5%) valves were most frequently affected. The right‐sided IE cases were all found in patients with congenital heart disease. The age of patients was younger in right‐sided cases than that in left‐sided ones (P = 0.001). There was no difference in the mortality among groups with different underlying heart disease (P = 0.841). Forty‐four (38.3%) patients were infected with viridans group streptococci. The isolation rate of staphylococci in right‐sided IE was higher than that in the left‐sided IE group (P = 0.021). More than 85% of streptococci were susceptible to β‐lactams.ConclusionsCongenital heart disease and degenerative valvular disease have overtaken rheumatic heart disease as the major underlying heart diseases associated with IE. Viridans group streptococci are the most common microbial cause of IE.
Impact of a decision rule on duration of continuous cardiac monitoring of patients with suspected acute coronary syndrome in an emergency department
Authors: King G. , Nicholls G. M. (M.) , Jones P. 
Published: July 2013

AbstractBackground/AimsTo determine the effect of introducing a decision rule on the duration of continuous cardiac monitoring (CCM) for patients with suspected acute coronary syndrome in an adult emergency department (ED).MethodsThis was a retrospective observational study of 220 patients with suspected acute coronary syndrome made up of two consecutive cohorts collected before and after introduction in July 2010 of a decision rule that made use of a new high‐sensitivity troponin T assay. The primary outcome was median CCM duration in the ED (CCMED). Secondary outcomes were median duration of CCM in the first 24 h, rate of adverse events, proportion of patients after the intervention who had the rule adhered to, and estimated median CCMED had the decision rule been adhered to by all patients.ResultsThe decision rule was adhered to in 59.3% (95% confidence interval 49.8–68.1) of patients post‐intervention. There was no statistically or clinically significant difference in median CCMED before (240 min, interquartile range 156–313) and after (230 min interquartile range 145–353) introduction of the decision rule (P = 0.74) nor in CCM in the first 24 h (908 min vs 929 min). Seven (3.2%, 95% confidence interval 1.4–6.6) adverse events occurred overall. All three patients with adverse events after the intervention were monitored in ED according to the decision rule.ConclusionIntroduction of this decision rule did not decrease the median CCMED. All adverse events after the intervention occurred in appropriately monitored patients, including patients with initially negative high‐sensitivity troponin T, suggesting that the decision rule would not compromise patient safety.
Implementation of risk stratified antibiotic therapy for neutropenic fever: what are the risks?
Authors: Wierema J. , Konecny P. , Links M. 
Published: July 2013

AbstractBackgroundA new national guideline for the management of febrile patients with severe neutropenia uses a risk stratification score to tailor treatment.AimsTo evaluate the implementation of this guideline in a metropolitan teaching hospital.MethodsA protocol was developed for implementation of the national guidelines for patients with neutropenic fever or at risk because of recent chemotherapy. Medical records of all patients presenting with fever to the haematology and oncology service for 3 months in 2011 were audited. Patients with a neutrophil count between 0.5 and 1.0 × 109/L were classified as borderline neutropenia.ResultsEighty‐one episodes of fever were treated on the protocol. Forty‐three per cent of patients were neutropenic. Uptake of the policy was low (35%) despite concerted efforts. The sensitivity and specificity of the Multinational Association for Supportive Care in Cancer score was 86% and 24% respectively. The readmission rate with fever was 19.2%. Median time to antibiotics was 60 min. Outcomes were similar for the neutropenic fever and borderline groups. Increasing treatment complexity was the major barrier to implementation.ConclusionsThe majority of presentations with cancer and fever following chemotherapy do not have neutropenia but have similar outcomes when treated on the same pathway. The utility of the Multinational Association for Supportive Care in Cancer score was limited by uptake and specificity. Reducing time to antibiotics administration and readmission rates were identified as priorities. Implementation was labour‐intensive and faced significant barriers. Prioritisation of evidence for translation requires attention to local priorities and implementation complexity. These results argue for a single sepsis guideline with treatment of cancer as a high‐risk group.
Facial skin breakdown in patients with non‐invasive ventilation devices: report of two cases and indications for treatment and prevention
Authors: Maruccia Michele , Ruggieri Martina , Onesti Maria G 
Published: July 2013

AbstractNon‐invasive ventilation (NIV) provides an effective ventilatory support in patients with respiratory failure without endotracheal intubation. However, there are potential problems with its clinical application and the development of pressure ulcers represents a common complication. Often several intensive care units treat facial skin breakdown related to NIV. In this article, we report our experience in treatment and prevention of these lesions, emphasising the higher risk of certain age groups to develop them, such as preterm infants and elderly patients with comorbidities. We performed daily disinfection of the lesions followed by application of topical cream containing hyaluronic acid (HA) sodium salt. In addition, in order to prevent worsening of injury, we applied a cushion made of gauze pad containing HA sodium salt between the skin and the masks, so as to reduce friction between the NIV devices and the skin. Local medical treatment allowed complete reepithelialisation of the injured skin areas. Systematic monitoring of patients' faces is essential to detect early damages and to intervene with appropriate therapy, especially in preterm infants and elderly. Moreover, refining the devices with the proposed protective cushion can reduce pressure ulcers and increase comfort for the patients.
Personality and Daily Experience: The Promise and the Challenge
Authors: Tennen Howard , Suls Jerry , Affleck Glenn 
Published: July 2013

ABSTRACTThis special issue of the Journal of Personality is devoted to personality and daily experience. Through historical analysis of the daily event literature, empirical inquiry, and methodological and statistical commentary, the contributors to this issue convey both the possibilities and the problems of studying everyday life. These articles demonstrate how people's dispositions, goals, and commitments can influence daily emotional well‐being and health, their inner experience, their reactions to events, and perhaps even which events they encounter. The introduction of personality to the study of daily experience holds the promise of enriching our studies of both.
Stabilization of the CORA Based Leveling Osteotomy for Treatment of Cranial Cruciate Ligament Injury Using a Bone Plate Augmented With a Headless Compression Screw
Authors: Raske Matthew , Hulse Don , Beale Brian , Saunders W. Brian , Kishi Erin , Kunze Christopher 
Published: July 2013

AbstractObjectiveTo report the effectiveness of a bone plate/headless compression screw (HCS) construct in preventing tibial plateau angle (TPA) shift postoperatively and to describe radiographic healing of the osteotomy.Study DesignCase series.AnimalsDogs (n = 31).MethodsRecords of dogs diagnosed with cranial cruciate ligament (CCL) injury treated with the center of rotation of angulation (CORA) based leveling osteotomy (CBLO) stabilized with a bone plate augmented with a HCS were reviewed. Breed, age, weight, and gender were recorded. Radiographs were reviewed for determination of preoperative tibial plateau angle (PreTPA), postoperative TPA (PostTPA), patellar tendon angle (PTA) postoperatively, and TPA at final evaluation (FinalTPA). Difference between PostTPA and FinalTPA was used to define any TPA shift. Radiographic healing at final evaluation was graded based on a 5‐point scale.ResultsMean time to final recheck was 88 days (range 49–237 days) with mean ± SD PreTPA = 28.6 ± 4.8°; PostTPA = 9.2 ± 2.2°; FinalTPA = 9.7 ± 2.6°; and TPA Shift = 0.52 ± 1.61°. There was no significant difference between PostTPA and FinalTPA (P = .084, power > 0.80). Mean postoperative PTA was 89.9 ± 1.7°. There were 2 implant related complications; 1 HCS migration and 1 HCS failure.ConclusionStabilization of the CBLO using a bone plate augmented with a HCS was effective in maintaining PostTPA and achieving satisfactory radiographic healing.
Foaling Rates After Surgical Repair of Ventral Cervical Lacerations Using a Trendelenburg Position in 18 Anesthetized Mares
Authors: Leary John Mark O' , Rodgerson Dwayne , Spirito Michael , Gomez Jorge 
Published: July 2013

ABSTRACTObjectiveTo (1) describe a surgical technique for repair of lacerations of the ventral aspect of the cervix in anesthetized mares in Trendelenburg position; and (2) report conception rates and foaling after repair.Study DesignCase series.AnimalsMares (n = 18).MethodsCervical lacerations were repaired in 2 layers with anesthetized mares in Trendelenburg position. The cervix was retracted caudally with stay‐sutures, and after excision of the healed margin of the laceration, the internal cervical mucosa and fibromuscular tissue were sutured in 1 layer with a continuous Lembert pattern. The external cervical mucosa was sutured using a simple‐continuous suture pattern. Number of foals produced by each mare before and after surgical repair was obtained from client/farm communication and from a commercial record keeping service.ResultsMean repair time for 1 laceration was 22 minutes and for 2 lacerations was 29 minutes. Nine mares conceived and 7 had at least 1 live healthy foal.ConclusionTrendelenburg position allows for efficient repair of a ventrally located cervical laceration in anesthetized mares.
Elemental Concentrations of Stream Sediments in Southern China
Authors: Zhizhong Cheng , Xuejing Xie , Hanjiang Pan , Rong Yang 
Published: July 2013

Over 3 million samples were collected from southern China at a density of 1–2 stream sediment samples per square kilometre as part of the Regional Geochemistry National Reconnaissance (RGNR) programme of China initiated in the late 1970s. Approximately 5244 composite samples of stream sediments from twelve provinces of southern China were prepared from the original RGNR samples collected from a territory with an area of 2300000 km2 at a density of one composite sample per 1:50000 map sheet (about 400 km2). Seventy‐six elements were determined by the geoanalysis laboratory of Henan Province (platinum‐group elements) and by the Institute of Geophysical and Geochemical Exploration (IGGE) laboratory for the remainder. Internal quality and external quality control methods were applied to ensure that the analytical data were comparable. Statistics were used to derive the mean and background values and indicate the average concentrations of the seventy‐six elements. Comparisons were made against the mean values obtained from stream sediments, floodplain sediments, overall sediments and overall soils of the entire territory of China. The concentrations of Hg, Cd, rare earth elements and 24 other elements were higher than their background for the whole of China. In contrast, the concentration of Na2O, CaO, Ba and Sr were lower in the stream sediments in southern China than their whole China background.
Isolation of lesbian, gay, bisexual and transgender youth: a dimensional concept analysis
Authors: Johnson Michael J. , Amella Elaine J. 
Published: July 2013

AbstractAimTo present the findings of a dimensional analysis of isolation in the context, and from the perspective, of lesbian, gay, bisexual and transgender youth.BackgroundLesbian, gay, bisexual and transgender youth are often at greater risk for negative health outcomes compared with heterosexual youth. Isolation is one risk factor cited throughout the literature; however, the concept is complicated and has many uses and thus warrants clarification.DesignConcept Analysis.Data SourcesSources comprise 35 English language research articles retrieved from CINAHL and EBSCOHost (1987–2012).MethodsA dimensional concept analysis was undertaken to analyse how the concept, isolation, is socially constructed.ResultsThis dimensional analysis revealed five socially constructed dimensions and four sub‐dimensions. These findings indicate that there is substantial variability in the concept of isolation. These differences and variations are most notably observed in the 20 articles (57%) that had more than one dimension. Although some of these articles were explicit with the different meanings and use of the concept, most of the papers had wide variability in the use and meaning of the concept.ConclusionThe disproportionately greater physical and mental health disparities between lesbian, gay, bisexual and transgender and heterosexual youth are a signal to conduct more research to clarify the concept of isolation, to develop instrumentation to identify at‐risk youth and to explore predictors and consequences of isolation. Nurses and others can lead the way in translating this knowledge into strategies that will improve the health and lives of these young people.
Measuring interpersonal continuity in high‐frequency home healthcare services
Authors: Gjevjon Edith R. , Eika Kari H , Romøren Tor Inge , Landmark Brynjar Fowels 
Published: July 2013

AbstractAimTo provide a method for assessing the degree of interpersonal continuity adapted to context and to measure and assess the degree of interpersonal continuity for long‐term recipients dependent on daily home health care.BackgroundInterpersonal continuity is important to the quality of care for long‐term dependents. In high‐frequency home healthcare services where patients receive daily care from many nurses or other health personnel over time, interpersonal continuity may be difficult to attain.DesignA cross‐sectional study with a descriptive design.MethodsInformation concerning 79 patients receiving long‐term frequent care was collected during four weeks in a maximum variation sample of Norwegian municipalities, from January 2009–May 2010. We measured interpersonal continuity objectively using indices of dispersion and the next‐day sequence of health personnel. For each measure, we computed the highest feasible level of continuity that could be attained in this home healthcare context given a standard shift plan. This level was then used as benchmark against which the actual level of continuity was assessed.ResultsPatients received on average 51 visits from a mean of 17 different carers during four weeks. The results revealed a low degree of interpersonal continuity in practice, far below what was feasible according to the benchmarks.ConclusionHigh‐frequency home health care was characterized by interpersonal discontinuity, but with potential for improvement. Objective measures of interpersonal continuity, when the benchmark is adapted to the context, are useful tools for planning and surveying continuity of care.
Parents' experiences with neonatal home care following initial care in the neonatal intensive care unit: a phenomenological hermeneutical interview study
Authors: Dellenmark‐Blom Michaela , Wigert Helena 
Published: July 2013

AbstractAimA descriptive study of parents' experiences with neonatal home care following initial care in the neonatal intensive care unit.BackgroundAs survival rates improve among premature and critically ill infants with an increased risk of morbidity, parents' responsibilities for neonatal care grow in scope and degree under the banner of family‐centred care. Concurrent with medical advances, new questions arise about the role of parents and the experience of being provided neonatal care at home.DesignAn interview study with a phenomenological hermeneutic approach.MethodsParents from a Swedish neonatal (n = 22) home care setting were extensively interviewed within one year of discharge. Data were collected during 2011–2012.FindingsThe main theme of the findings is that parents experience neonatal home care as an inner emotional journey, from having a child to being a parent. This finding derives from three themes: the parents' experience of leaving the hospital milieu in favour of establishing independent parenthood, maturing as a parent and processing experiences during the period of neonatal intensive care.ConclusionsThis study suggests that neonatal home care is experienced as a care structure adjusted to incorporate parents' needs following discharge from a neonatal intensive care unit. Neonatal home care appears to bridge the gap between hospital and home, supporting the family's adaptation to life in the home setting. Parents become empowered to be primary caregivers, having nurse consultants serving the needs of the whole family. Neonatal home care may therefore be understood as the implementation of family‐centred care during the transition from NICU to home.
The changing face of aggression: the effect of personalized avatars in a violent video game on levels of aggressive behavior
Authors: Hollingdale Jack , Greitemeyer Tobias 
Published: July 2013

AbstractVideo game developments allow players to design their own personalized avatars. Previous research has shown that this capability increases levels of aggression within socially acceptable forms of violence. Using the general aggression model (GAM), the current study examined the effect of avatar personalization on behavioral aggression within a violent video game. Participants who played a violent video game and designed their own avatars were significantly more aggressive than those who played the same violent video game with a generic avatar, and were also more aggressive than those who played the nonviolent video game, regardless of whether or not they designed their own personalized characters. Limitations and directions for future research are discussed.
Phylogeography of the supralittoral isopodLigia occidentalisaround the Point Conception marine biogeographical boundary
Authors: Eberl Renate , Mateos Mariana , Grosberg Richard K. , Santamaria Carlos A. , Hurtado Luis A. 
Published: July 2013

AbstractAimThe Point Conception (PC) biogeographical boundary is defined by a transition between cold northern and warm southern water masses, accompanied by shifts in numerous ecological and environmental parameters. While these factors can potentially contribute to the genetic differentiation of lineages whose distributions span this boundary, few organisms exhibit genetic signatures of restricted gene flow across this region. We examine the effects of thePCboundary and other potential dispersal barriers on phylogeographical patterns in the rocky supralittoral isopodLigia occidentalis. This isopod has a limited dispersal potential, its distribution spans thePCregion, and it exhibits high levels of allopatric genetic differentiation south ofPC.LocationEasternPacific coastline between southernOregon and theBajaCaliforniaPeninsula.MethodsWe conducted a thorough sampling ofL. occidentalisfrom thePCarea to its northern range limit in southernOregon, and increased previous sampling coverage south ofPC. We obtained sequences of the mitochondrial genes cytochromecoxidase subunit I (COI) and 16SrDNAfor the new localities and combined them with a previously published data set, resulting in a total of 58 sampling locations. We also obtained sequences of the nuclear gene sodium–potassiumATPase α‐subunit (NaK). We conducted phylogenetic and population‐genetic analyses.ResultsThe geographical limit between the two most divergent clades ofL. occidentalis(20–25% divergence forCOI) distributed between southernOregon and theBajaCaliforniaPeninsula occurs at thePCbiogeographical boundary. Levels of allopatric genetic divergences were greatly reduced north ofPC(≤ 3.0% divergence forCOI).Main conclusionsThe geographical limit between the two mainL. occidentalisclades inCalifornia largely reflects the changes in sea surface temperature that define thePCbiogeographical boundary. Reduced levels of genetic divergence amongL. occidentalislineages found north ofPCsuggest a recent expansion in the northern range of this isopod.
Electrocardiographic Predictors of Electroanatomic Scar Size in Arrhythmogenic Right Ventricular Cardiomyopathy: Implications for Arrhythmic Risk Stratification
Authors: ZORZI ALESSANDRO , MIGLIORE FEDERICO , ELMAGHAWRY MOHAMED , SILVANO MARIA , MARRA MARTINA PERAZZOLO , NIERO ALICE , NGUYEN KIM , RIGATO ILARIA , BAUCE BARBARA , BASSO CRISTINA , THIENE GAETANO , ILICETO SABINO , CORRADO DOMENICO 
Published: July 2013

ECG Predictors of Electroanatomic Scar in ARVCIntroductionThe extent of right ventricular (RV) electroanatomic scar (EAS) detected by endocardial voltage mapping (EVM) is a powerful invasive predictor of arrhythmic outcome in patients with arrhythmogenic right ventricular cardiomyopathy (ARVC). Electrocardiogram (ECG) and signal‐averaged ECG are noninvasive tools of established clinical value for the diagnosis of electrical abnormalities in ARVC. This study was designed to assess the role of ECG and SAECG abnormalities for noninvasive estimation of the extent and regional distribution of RV‐EAS and prediction of scar‐related arrhythmic risk.Methods and ResultsThe study population included 49 consecutive patients (38 males, median age 35 years) with a definite diagnosis of ARVC and an abnormal EVM by CARTO system. At univariate analysis, the presence of epsilon waves, the degree of RV dilation, the severity of RV dysfunction, and the extent of negative T waves correlated with RV‐EAS% area. Normal T‐waves were associated with a median RV‐EAS% area of 4.9% (4.5–6.4), negative T waves in V1–V3 of 22.0% (8.5–30.6), negative T waves in V1–V3 extending to lateral precordial leads (V4–V6) of 26.8% (11.5–35.2), and negative T waves in both precordial (V2–V6) and inferior leads of 30.2% (24.8–33.0) (P < 0.001). At multivariate analysis, the extent of negative T waves remained the only independent predictor of RV‐EAS% area (B = 4.4, 95%CI 1.3–7.4, P = 0.006) and correlated with the arrhythmic event‐rate during follow‐up (P = 0.03).ConclusionsIn patients with ARVC, the extent of negative T‐waves across 12‐lead ECG allows noninvasive estimation of the amount of RV‐EAS and prediction of EAS‐related arrhythmic risk.