bluuebunny/crossref_metadata_2025_split huggingface dataset:
Long-period rhythmic synchronous firing in a scale-free network
Authors: Mi Yuanyuan , Liao Xuhong , Huang Xuhui , Zhang Lisheng , Gu Weifeng , Hu Gang , Wu Si 
Published: November 2013

Significance
Understanding the mechanisms of how neural systems process temporal information is at the core to elucidate brain functions, such as for speech recognition and music appreciation. The present study investigates a simple yet effective mechanism for a neural system to extract the rhythmic information of external inputs in the order of seconds. We propose that a large-size neural network with scale-free topology is like a repertoire, which consists of a large number of loops and chains with various sizes, and these loops and chains serve as substrates to learn the rhythms of external inputs.
Unintended imitation affects success in a competitive game
Authors: Naber Marnix , Vaziri Pashkam Maryam , Nakayama Ken 
Published: November 2013

Significance
People have a strong tendency to imitate each other in social interaction. Here, we show that imitation is also persistent in a competitive context. In our experiments, participants performed a two-player arcade game in which they could win money when they quickly hit targets on a touchscreen before their opponent. We demonstrate that reaction times and movements of players were highly synchronized and the financial rewards could not withhold players from imitating slow opponents. Imitation persisted, even when there was no need to follow the opponent’s actions.
Synthesis and delivery of short, noncoding RNA by B lymphocytes
Authors: Almanza Gonzalo , Anufreichik Veronika , Rodvold Jeffrey J. , Chiu Kevin T. , DeLaney Alexandra , Akers Johnny C. , Chen Clark C. , Zanetti Maurizio 
Published: November 2013

SignificanceShort, noncoding RNAs are a powerful way to regulate gene expression. As such, they are potential candidates for new forms of therapy. However, clinical translation is still hampered by lack of suitable and cost-effective delivery methods. Here we demonstrate that primary B lymphocytes can be programmed with plasmid DNA, effectively and easily, for the synthesis and delivery of antisense sequences (anti-microRNA) in vitro and in vivo. We also demonstrate that anti-microRNAs secreted by primary B lymphocytes in vivo are taken up by T lymphocytes during antigen activation. These initial observations predict that microRNA-based intervention to modulate immune responses or to target cancer cell growth may be possible through the type of cell-based therapy disclosed here.
Spectral redemption in clustering sparse networks
Authors: Krzakala Florent , Moore Cristopher , Mossel Elchanan , Neeman Joe , Sly Allan , Zdeborová Lenka , Zhang Pan 
Published: November 2013

Significance
Spectral algorithms are widely applied to data clustering problems, including finding communities or partitions in graphs and networks. We propose a way of encoding sparse data using a “nonbacktracking” matrix, and show that the corresponding spectral algorithm performs optimally for some popular generative models, including the stochastic block model. This is in contrast with classical spectral algorithms, based on the adjacency matrix, random walk matrix, and graph Laplacian, which perform poorly in the sparse case, failing significantly above a recently discovered phase transition for the detectability of communities. Further support for the method is provided by experiments on real networks as well as by theoretical arguments and analogies from probability theory, statistical physics, and the theory of random matrices.
Anthropogenic emissions of methane in the United States
Authors: Miller Scot M. , Wofsy Steven C. , Michalak Anna M. , Kort Eric A. , Andrews Arlyn E. , Biraud Sebastien C. , Dlugokencky Edward J. , Eluszkiewicz Janusz , Fischer Marc L. , Janssens-Maenhout Greet , Miller Ben R. , Miller John B. , Montzka Stephen A. , Nehrkorn Thomas , Sweeney Colm 
Published: November 2013

Significance
Successful regulation of greenhouse gas emissions requires knowledge of current methane emission sources. Existing state regulations in California and Massachusetts require ∼15% greenhouse gas emissions reductions from current levels by 2020. However, government estimates for total US methane emissions may be biased by 50%, and estimates of individual source sectors are even more uncertain. This study uses atmospheric methane observations to reduce this level of uncertainty. We find greenhouse gas emissions from agriculture and fossil fuel extraction and processing (i.e., oil and/or natural gas) are likely a factor of two or greater than cited in existing studies. Effective national and state greenhouse gas reduction strategies may be difficult to develop without appropriate estimates of methane emissions from these source sectors.
Limitations of inclusive fitness
Authors: Allen Benjamin , Nowak Martin A. , Wilson Edward O. 
Published: November 2013

Significance
Inclusive fitness theory is the idea that the evolutionary success of a trait can be calculated as a sum of fitness effects multiplied by relatedness coefficients. Despite recent mathematical analyses demonstrating the limitations of this approach, its adherents claim that it is as general as the theory of natural selection itself. This claim is based on using linear regression to split an individual's fitness into components due to self and others. We show that this regression method is useless for the prediction or interpretation of evolutionary processes. In particular, it fails to distinguish between correlation and causation, leading to misinterpretations of simple scenarios. The weaknesses of the regression method underscore the limitations of inclusive fitness theory in general.
Eliminating Central Line–Associated Bloodstream Infections: A National Patient Safety Imperative
Authors: Berenholtz Sean M. , Lubomski Lisa H. , Weeks Kristina , Goeschel Christine A. , Marsteller Jill A. , Pham Julius C. , Sawyer Melinda D. , Thompson David A. , Winters Bradford D. , Cosgrove Sara E. , Yang Ting , Louis Thomas A. , Lucas Barbara Meyer , George Christine T. , Watson Sam R. , Albert-Lesher Mariana I. , Andre Justin R. St. , Combes John R. , Bohr Deborah , Hines Stephen C. , Battles James B. , Pronovost Peter J. ,   on behalf of the On the CUSP: Stop BSI program
Published: November 2013

Background.Several studies demonstrating that central line–associated bloodstream infections (CLABSIs) are preventable prompted a national initiative to reduce the incidence of these infections.Methods.We conducted a collaborative cohort study to evaluate the impact of the national “On the CUSP: Stop BSI” program on CLABSI rates among participating adult intensive care units (ICUs). The program goal was to achieve a unit-level mean CLABSI rate of less than 1 case per 1,000 catheter-days using standardized definitions from the National Healthcare Safety Network. Multilevel Poisson regression modeling compared infection rates before, during, and up to 18 months after the intervention was implemented.Results.A total of 1,071 ICUs from 44 states, the District of Columbia, and Puerto Rico, reporting 27,153 ICU-months and 4,454,324 catheter-days of data, were included in the analysis. The overall mean CLABSI rate significantly decreased from 1.96 cases per 1,000 catheter-days at baseline to 1.15 at 16–18 months after implementation. CLABSI rates decreased during all observation periods compared with baseline, with adjusted incidence rate ratios steadily decreasing to 0.57 (95% confidence intervals, 0.50–0.65) at 16–18 months after implementation.Conclusion.Coincident with the implementation of the national “On the CUSP: Stop BSI” program was a significant and sustained decrease in CLABSIs among a large and diverse cohort of ICUs, demonstrating an overall 43% decrease and suggesting the majority of ICUs in the United States can achieve additional reductions in CLABSI rates.
Managing fisheries from space: Google Earth improves estimates of distant fish catches
Authors: Al-Abdulrazzak Dalal , Pauly Daniel 
Published: November 2013

Abstract
Global fisheries are overexploited worldwide, yet crucial catch statistics reported to the Food and Agriculture Organization (FAO) by member countries remain unreliable. Recent advances in remote-sensing technology allow us to view fishing practices from space and mitigate gaps in catch reporting. Here, we use Google Earth to count intertidal fishing weirs off the coast of six countries in the Persian Gulf, otherwise known as the Arabian Gulf. Although the name of this body of water remains contentious, we use the name used in Google Earth. Combining, in a Monte Carlo procedure, the number of weirs (after correcting for poor resolution and imagery availability) with assumptions about daily catch and fishing season lengths, we estimate that 1900 (±79) weirs contribute to a regional catch up to six times higher than the officially reported catches of 5260 t. These results, which speak to the unreliability of officially reported fisheries statistics, provide the first example of fisheries catch estimates from space, and point to the potential for remote-sensing approaches to validate catch statistics and fisheries operations in general.
The Ddx5 and Ddx17 RNA helicases are cornerstones in the complex regulatory array of steroid hormone-signaling pathways
Authors: Samaan Samaan , Tranchevent Léon-Charles , Dardenne Etienne , Polay Espinoza Micaela , Zonta Eleonora , Germann Sophie , Gratadou Lise , Dutertre Martin , Auboeuf Didier 
Published: November 2013

AbstractEstrogen and androgen receptors (ER and AR) play key roles in breast and prostate cancers, respectively, where they regulate the transcription of large arrays of genes. The activities of ER and AR are controlled by large networks of protein kinases and transcriptional coregulators, including Ddx5 and its highly related paralog Ddx17. The Ddx5 and Ddx17 RNA helicases are also splicing regulators. Here, we report that Ddx5 and Ddx17 are master regulators of the estrogen- and androgen-signaling pathways by controlling transcription and splicing both upstream and downstream of the receptors. First, Ddx5 and Ddx17 are required downstream of ER and AR for the transcriptional and splicing regulation of a large number of steroid hormone target genes. Second, Ddx5 and Ddx17 act upstream of ER and AR by controlling the expression, at the splicing level, of several key regulators of ER and AR activities. Of particular interest, we demonstrate that Ddx5 and Ddx17 control alternative splicing of the GSK3β kinase, which impacts on both ER and AR protein stability. We also provide a freely available online resource which gives information regarding splicing variants of genes involved in the estrogen- and androgen-signaling pathways.
The Basic Leucine Zipper Transcription Factor ABSCISIC ACID RESPONSE ELEMENT-BINDING FACTOR2 Is an Important Transcriptional Regulator of Abscisic Acid-Dependent Grape Berry Ripening Processes
Authors: Nicolas Philippe , Lecourieux David , Kappel Christian , Cluzet Stéphanie , Cramer Grant , Delrot Serge , Lecourieux Fatma 
Published: November 2013

AbstractIn grape (Vitis vinifera), abscisic acid (ABA) accumulates during fruit ripening and is thought to play a pivotal role in this process, but the molecular basis of this control is poorly understood. This work characterizes ABSCISIC ACID RESPONSE ELEMENT-BINDING FACTOR2 (VvABF2), a grape basic leucine zipper transcription factor belonging to a phylogenetic subgroup previously shown to be involved in ABA and abiotic stress signaling in other plant species. VvABF2 transcripts mainly accumulated in the berry, from the onset of ripening to the harvesting stage, and were up-regulated by ABA. Microarray analysis of transgenic grape cells overexpressing VvABF2 showed that this transcription factor up-regulates and/or modifies existing networks related to ABA responses. In addition, grape cells overexpressing VvABF2 exhibited enhanced responses to ABA treatment compared with control cells. Among the VvABF2-mediated responses highlighted in this study, the synthesis of phenolic compounds and cell wall softening were the most strongly affected. VvABF2 overexpression strongly increased the accumulation of stilbenes that play a role in plant defense and human health (resveratrol and piceid). In addition, the firmness of fruits from tomato (Solanum lycopersicum) plants overexpressing VvABF2 was strongly reduced. These data indicate that VvABF2 is an important transcriptional regulator of ABA-dependent grape berry ripening.
Culture matters
Authors: Hwang Jiyoung , Chung Jae-Eun , Jin Byungho 
Published: November 2013

Purpose– This study aims to examine unique cultural influences in the context of buyer-supplier relationships in a Confucian culture. The paper identifies whether and how long-term orientation (LO), an inherent value of Confucianism, is an antecedent of important factors of channel relationships, rather than a relationship outcome and whether and how market orientation mediates relations among LO and other relational factors.Design/methodology/approach– Data were collected from retail buyers at department stores in South Korea, a country that is representative of Confucian culture. One hundred and fourteen valid cases were analysed using path analysis to assess the proposed model.Findings– LO plays significant anteceding roles in market orientation, trust, and economic dependence, both directly and indirectly. In addition, market orientation mediates the impact of LO on trust and economic dependence.Research limitations/implications– Testing the proposed model with both retailers' and suppliers' data will add robustness to the research findings. This research advances the understanding of cultural influence on channel relationship regarding the role of LO and market orientation. Strategic practical implications include that marketers who deal with business partners in Confucian culture need to understand the embeddedness of LO and its impact on business relationship management.Originality/value– The current study scrutinizes unique aspects of cultural influence on the anteceding roles of LO and the direct relationship between LO and market orientation in Confucian culture. The findings on the cultural embeddedness of LO provide novel insights; they also provide managerial implications for Western marketers in how to better deal with Confucian business partners.
Bioenergy prospects in Taiwan using set-aside land – an economic evaluation
Authors: Kung Chih-Chun , McCarl Bruce , Cao Xiaoyong , Xie Hualin 
Published: November 2013

Purpose
– This study aims to explore Taiwan's potential for bioenergy production using feedstocks grown on set-aside land and discusses the consequent effects on Taiwan's energy security plus benefits and greenhouse gas (GHG) emission.

Design/methodology/approach
– The Modified Taiwan Agricultural Sector Model (Modified TASM), based on price endogenous mathematical programming, was used to simulate different agricultural policies related to bioenergy production. To do this simulation, the TASM model was extended to include additional bioenergy production possibilities and GHG accounting.

Findings
– Taiwan's bioenergy production portfolio depends on prices of ethanol, electricity and GHG. When GHG prices go up, ethanol production decreases and electricity production increases because of the relatively stronger GHG offset power of biopower.

Originality/value
– Taiwan is interested in producing bioenergy but only limited information is available. This study provides the information on potential bioethanol and bioelectricity production from various energy crops, GHG emission offset from bioenergy, and regional energy security.
Production pattern, transaction style and raw milk quality
Authors: Zhong Zhen , Chen Shufen , Kong Xiangzhi 
Published: November 2013

Purpose
– The purpose of this paper is to present an econometric model to empirically analyze the influence of production patterns and transaction style on raw milk quality. More specifically, the paper examines the effects of these institutions on both nutrition and safety aspects of raw milk quality.

Design/methodology/approach
– Using data collected from 396 households in Inner Mongolia, this paper adopts a multiple linear regression model (OLS/FGLS) and a zero-inflated Poisson regression model to test two hypotheses proposed according to theory and descriptive analysis.

Findings
– The empirical results indicate that both production pattern and transaction style significantly affect raw milk quality. Production pattern has a more significant effect on raw milk nutrition, while transaction style has a more significant effect on raw milk safety.

Research limitations/implications
– Current government policies focus on reducing household production and regulating private milk collection stations. From a comprehensive quality perspective, these policies are not effective in that they cannot guarantee raw milk safety and have little effect on improving raw milk nutrition. Alternatively, promoting dairy farmers' specialized cooperatives may be a more effective policy measure.

Originality/value
– In contrast to other studies, this paper adopts a comprehensive quality perspective that examines both nutritional and safety characteristics rather than focusing on any single quality indicator, separately analyzing the factors influencing raw milk nutrition and raw milk safety. Therefore, the conclusion of this paper provides a new perspective in addressing the current raw milk quality problems facing China's dairy industry.
Examining how preferences for employer branding attributes differ from entry to exit and how they relate to commitment, satisfaction, and retention
Authors: K. Ito Jack , M. Brotheridge Céleste , McFarland Kathie 
Published: November 2013

Purpose– The aim of this paper is to address three broad questions: Are preferences for branding attributes similar for entry and for retention? Are there generational and career stage differences in one's entry and exit priorities? How is current satisfaction with brand image attributes related to overall commitment, satisfaction and retention?Design/methodology/approach– This paper reports on the results of a survey of 144 workers employed at 37 day care centers in a medium sized Canadian city.Findings– Although the level of respondents' priorities for entry and exit differed, most priorities remained in the same order. However, their perspectives were more disaggregated for entry than for exit, where branding attributes were more strongly correlated. Consistent with the exploration stage of career development, younger people planned to stay a shorter length of time with a particular center.Research limitations/implications– This study includes only child care workers in a small geographic region. Future research should be undertaken in larger scale firms that also offer greater heterogeneity in professions as well as career options. Also, a longitudinal study that follows new entrants for several years, using both instrumental and symbolic measures, would provide information on what attracted individuals and what influenced their intention to leave.Practical implications– Although there were few differences by age or career stage, the variation within each factor suggests that a brand image may need to be relatively broad to accommodate diversity. HR practitioners can use the practice symbolic pattern to build and maintain a culture that is attractive to present and prospective employees. The opposite symbolic practice pattern may help current employees understand reasons for new practices.Originality/value– Organizations face significant challenges in designing programs for recruitment and retention. This study considers how employees' to two questions – “why do people enter the organization” and “why do people remain?” – may differ.
Hedging in nursing and education academic articles
Authors: Rabab'ah Ghaleb 
Published: November 2013

Purpose
– The study aims to investigate how and why hedges are used in nursing and education academic research articles and find out whether there are differences between the two disciplines in using hedges and their subcategories.

Design/methodology/approach
– The realization of hedges in 50 academic articles representing both disciplines, namely education and nursing, was scrutinized and analyzed.

Findings
– The study reveals that there are significant differences between the nursing and education writers' use of hedging in the total use of hedging devices and their subcategories, in favor of the education discipline. This indicates that writers of education articles use hedges more frequently than the writers of nursing articles. In support of previous literature, it concludes that hedging devices are used as communicative strategies to qualify writers' commitment, reduce the force of the researchers' statements, express probability, save the writers' face, persuade readers, and avoid any possible rejection of their statements.

Research limitations/implications
– The study was limited to 50 research articles representing both disciplines: education (non-scientific genre) and nursing (scientific genre), and certain hedging devices and their subcategories.

Practical implications
– The study recommends that a clear awareness of the pragmatic effect of hedges and the ability to recognize them in texts is crucial to the acquisition of rhetorical competence in any discipline.

Originality/value
– Despite the significance of hedging and the extensive research conducted on hedging, no studies have been conducted on nursing and education academic research articles to see how and why hedges are used in these two disciplines. The results can add to the existing literature that this rhetorical strategy is used differently in different disciplines and make an important contribution to the understanding of the practical reasoning and persuasion in nursing and education.
Innovation and business performance of SMEs: the case of Dubai
Authors: Al-Ansari Yahya , Pervan Simon , Xu Jun 
Published: November 2013

Purpose– The study aims to explore the innovative characteristics of small- and medium-sized enterprises (SMEs) and the link between their innovation and business performance in the emerging Dubai market in the United Arab Emirates.Design/methodology/approach– Using data from 200 SMEs, the study utilizes a structured survey that was developed from a methodical literature review. Both descriptive and inferential statistics were used to evaluate the findings.Findings– The findings described the innovative characteristics of SMEs and suggested that there is a significant positive link between innovation and business performance.Research limitations/implications– The study offers SMEs with innovative behaviors a better perspective of their business and market environments. However, the study is limited to SMEs operating in the Dubai marketplace. Future research could also look at other markets and use qualitative research methods.Originality/value– The study provides important insights that could guide SMEs in their understanding of innovation and its benefit in emerging markets. The findings reinforce the growing empirical evidence of the positive impact of innovation on business performance. The findings also challenge the assumption that innovation drains resources in emerging markets.