bluuebunny/crossref_metadata_2025_split huggingface dataset:
Noradrenaline induces binding of Clathrin light chain A to α1‐adrenoceptors in the human prostate
Authors: Hennenberg Martin , Miersch Josef , Rutz Beata , Strittmatter Frank , Waidelich Raphaela , Stief Christian G. , Gratzke Christian 
Published: March 2013

AbstractBACKGROUNDBinding of clathrins or caveolin to G protein‐coupled receptors may induce post‐translational modifications of receptor function. Receptor regulation by clathrin requires cofactors ADP‐ribosylation factor 6 (ARF6) and adaptin, while dynamin is required for clathrin‐ and caveolin‐dependent mechanisms.OBJECTIVETo investigate the expression and α1‐adrenoceptor binding of clathrins, caveolin, and their cofactors in the human prostate.METHODSProstate tissue was obtained from radical prostatectomy. Expression of clathrin heavy chain (HC), clathrin light chain A and B (LCA, LCB), caveolin‐1, ARF6, β‐adaptin, and dynamin‐2 was studied by RT‐PCR, Western blot, immunohistochemistry, and fluorescence staining. Interaction of α1A‐adrenoceptors with clathrins and caveolin‐1 was studied by coimmunoprecipitation.RESULTSmRNA and protein expression of clathrin HC, LCA, LCB, caveolin‐1, dynamin‐2, and β‐adaptin was detected in prostate tissues of each patient. Immunohistochemistry demonstrated the expression of clathrin HC, LCA, LCB, caveolin, dynamin, and β‐adaptin in stromal cells. Immunoreactivity for these proteins colocalized with α‐smooth muscle actin and α1A‐adrenoceptors in double fluorescence staining. Coimmunoprecipitation demonstrated that α1A‐adrenoceptors in prostate tissue interact with clathrin HC and LCB under resting conditions, but not with caveolin‐1. Stimulation of prostate tissues with noradrenaline (30 µM) in vitro induced binding of clathrin LCA to α1A‐adrenoceptors.CONCLUSIONSThe prostatic α1‐adrenoceptor population is at least partially bound to clathrin HC and LCB. Upon receptor activation, prostate α1A‐adrenoceptors bind clathrin LCA. This points to a new concept of post‐translational α1‐adrenoceptor regulation in the prostate, which includes receptor interaction with accessory binding partners. Prostate 73: 715–723, 2013. © 2013 Wiley Periodicals, Inc.
Preparation of epitaxial films of the transparent conductive oxide Al:ZnO by reactive high‐pressure sputtering in Ar/O2 mixtures
Authors: Van Gompel M. , Conings B. , Jiménez Monroy K. L. , D‘Haen J. , Gilissen K. , D‘Olieslaeger M. , Van Bael M. K. , Wagner P. 
Published: March 2013

AbstractTransparent conductive metal oxides are interesting materials for various optoelectronic applications including solar cells and flat panel displays. This study focuses on the in situ deposition of aluminum‐doped zinc oxide (AZO) thin layers on c‐axis oriented sapphire substrates by dc sputtering and on the structural and electrical characterization. The films have a typical thickness of 90 nm and a roughness of 10 nm root mean square. An Al/Zn ratio of 2.4 at% Al was determined by X‐ray photoelectron spectroscopy. X‐ray diffraction shows a preferential growth in the (0002) c‐axis direction. Films have an average transparency of 90% in the visible‐light spectrum, a room‐temperature resistivity of 3.7 × 10−3 Ω cm and a carrier mobility of 6.7 cm2 V−1 s−1.
THz photoconductivity in a‐Si:H
Authors: Shimakawa Koichi , Wagner Tomas , Frumar Miloslav 
Published: March 2013

Abstractmagnified imageAlthough the steady‐state secondary photoconductivity in amorphous semiconductors is fairly well understood, photocarrier transport with a subpicosecond time resolution (the THz region in the frequency domain) is still not clear. The frequency response of short‐lived photocarriers in the THz region is discussed in a‐Si:H here. It is shown that THz‐photoconductivity is highly influenced by the mesoscopic inhomogeneity (10‐nm scale) originating from potential fluctuations. This behavior is basically the same as observed in the radio‐frequency (RF) range.
Optical probe for surface and subsurface defects induced by ion bombardment
Authors: Sun L. D. , Hohage M. , Zeppenfeld P. 
Published: March 2013

AbstractWe demonstrate that reflectance difference spectroscopy (RDS) is sensitive to defects induced by ion bombardment, located either in the topmost layer or in the subsurface region. Most importantly, these two kinds of defects can be spectrally discriminated, since the corresponding signatures in the RD spectrum arise from perturbations of different types of electronic states: The defects in the topmost surface layer mainly lead to a quenching of the optical anisotropy related to surface states, whereas the subsurface defects strongly affect the optical anisotropy originating from transitions between surface‐modified bulk electronic states. Consequently, RDS can be used to simultaneously monitor the defects in the topmost surface layer and in the subsurface region in‐situ during ion bombardment and thermal annealing.magnified imageCharacteristic RD spectra and the corresponding STM images for a Cu(110) substrate before and after healing of the subsurface defects.(© 2013 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Validation of the femoral component placement during hip resurfacing: a comparison between the conventional jig, patient‐specific template, and CT‐based navigation
Authors: Kitada Makoto , Sakai Takashi , Murase Tsuyoshi , Hanada Toshihisa , Nakamura Nobuo , Sugano Nobuhiko 
Published: March 2013

AbstractBackgroundAppropriate insertion of a femoral guidewire is essential for hip resurfacing. A simulation study was planned using synthetic femoral bone models and the accuracy and precision of femoral guidewire alignment and insertion point were compared between conventional jigs, patient‐specific templates, and computed tomography (CT) based navigation techniques.MethodsAnteversion, stem‐shaft angle, and the three‐dimensional insertion point were measured postoperative with CT. Errors between planned and postoperative measurement and precision were evaluated.ResultsThere were no statistically significant differences in error for anteversion or insertion point, although the mechanical jig showed greater error in the stem‐shaft angle than the others. Patient‐specific template and CT‐based navigation showed good precision with high intraclass correlation (ICC) (template, 0.908 to 1.000; navigation, 0.929 to 0.995) and small root mean square error (RMSE) (0.954 to 2.969; 1.468 to 3.213). The mechanical jig group performance was inferior to the others.ConclusionsPatient‐specific templates and CT‐based navigation had good accuracy and precision. The mechanical jig technique was inferior to the others. Copyright © 2013 John Wiley & Sons, Ltd.
Interference percolation
Authors: Balister Paul , Bollobás Béla 
Published: March 2013

AbstractLet G be an infinite connected graph with minimum degree δ and maximum degree Δ. Let Gp be a random induced subgraph of G obtained by selecting each vertex of G independently with probability p, , and let be the induced subgraph of Gp obtained by deleting all vertices of Gp with degree greater than k in Gp. We show that if and is not too large then almost surely has no infinite component. Moreover, this result is essentially best possible since there are examples where has an infinite component (a) when , 4, or 5, and k = 3; (b) when for any δ and k = 3; and (c) when for any and . In addition, we show that if G is the d‐dimensional lattice then almost surely has an infinite component for sufficiently large d. © 2014 Wiley Periodicals, Inc. Random Struct. Alg. 44, 399–418, 2014
Waldschlößchenbrücke in Dresden – Ausführungsplanung des Überbaus
Authors: Klähne Thomas , Einhäuser Oliver 
Published: March 2013

AbstractDie Waldschlößchenbrücke in Dresden ist die lang gedachte, nun erbaute neue Elbquerung, über deren Notwendigkeit schon unsere Vorväter diskutierten – die Diskussionen brechen bis heute nicht ab. Sie sind politischer, ästhetischer, wirtschaftlicher und technischer Art.Die Brücke ist ein markantes Zeichen deutscher Ingenieurkunst. Sie ist geometrisch anspruchsvoll und daher in ihrer Konstruktion sehr detailreich. In ihrer Herstellung und Montage war sie ein mutiges Unterfangen. Im vorliegenden Beitrag wird über die technische Bearbeitung und Ausführung des Stahlverbundüberbaus sowie der stählernen Stützen berichtet.The Waldschlößchen Bridge in Dresden, Germany – Plan of execution of the superstructure. The Waldschlößchen Bridge in Dresden is the long imagined, now built, crossing of the river Elbe, the necessity of which was already discussed by our forefathers. The discussion continues to this day. They were and are of political, aesthetical, economical and technical character. The new bridge is a remarkable example of German engineering. It is geometrically challenging, hence very detailed in the construction, which made the manufacture and installation a bold undertaking. This paper will cover the technical process and execution of both the composite steel superstructure, and the steel supports.
Tragverhalten von plattenartigen Tragelementen mit ein‐ und mehrlagigen Faltungen aus Feinblech
Authors: Trautz Martin , Herkrath Ralf , Puppa Giovanni Della , Buffart Henry 
Published: March 2013

AbstractDer Einsatz von Feinblech für tragende Konstruktionen im Bauwesen ist bisher weniger weit verbreitet und beschränkt sich in Form von Halbzeugen auf Well‐ oder Falzbleche oder auf Sonderbauweisen wie etwa geodätische Kuppeln, hemisphärische, in Anlehnung an Polyedergeometrien gefaltete Hüllen aus dünnem Blech. Neben solchen räumlich gekrümmten Faltkonstruktionen, deren Lastabtragung – ähnlich Schalentragwerken – überwiegend über Normalkraftbeanspruchung erfolgt, sind auch biegebelastete Tragwerke aus gefalteten dünnen Blechen in Kombination mit ebenen Blechen in einer oder in mehreren Lagen als Leichtbaukonstruktion denkbar. Entscheidend für die Effizienz in Bezug auf das Tragverhalten solcher so genannter Faltleichtbauplatten ist einerseits die Wahl der Faltungstypologie und Faltungsausbildung hinsichtlich Faltungshöhe und ‐frequenz, andererseits die Wahl der Blechdicke. Letztere hängt von der lokalen Beulgefahr und den Spannungen ab. Um das statisch nutzbare Potential solcher biegebeanspruchter Tragelemente aus Feinblech auszuloten, werden im vorliegenden Artikel die Ergebnisse von Untersuchungen im Rahmen einer Parameterstudie an ein‐ und mehrlagigen Longitudinal‐ und Punktfaltungen auf ihre auf das Eigengewicht bezogene Tragfähigkeit vorgestellt, Konstruktionsgrundsätze abgeleitet und Einsatzmöglichkeiten aufgezeigt.Load‐bearing characteristics of plate‐like elements with single and multi‐layered folded structures of steel sheets. The application of steel sheet for load‐bearing constructions is currently rather uncommon. Nowadays, steel sheet for load‐bearing constructions is only used for corrugated sheeting or for special constructions such as geodesic domes; hemispherical, folded envelopes made out of thin steel sheet that have been invented by the architect R. Buckminster Fuller. Beside these spatially‐curved folding constructions, whose load is mainly transferred by axial force, bearing structures composed out of thin, folded sheets with one or more layers as a light‐weight structure are also possible. Crucial for their load bearing behavior and their efficiency is on the one hand the choice of the folding typology regarding folding height and frequency and on the other hand the sheet thickness, which depends on the local load factor. The present article shows the potential of bending‐loaded bearing structures by presenting the results of parametric studies. In the context of these parametric studies, single‐ and multi‐layered longitudinal foldings and point foldings made of steel sheet have been examined towards their bearing capacity. Construction principles as well as potential uses have also been perused.
Theory and case study of vehicle load identification based on BWIM of steel truss bridge
Authors: Chen Weizhen , Yang Guang 
Published: March 2013

AbstractIn China recent accidents involving sudden collapses of bridges have aroused great concern about real traffic loads and the loadbearing capacities of existing bridges. However, the proper management of such bridges relies on accurate information on bridge operating loads, which is essential for assessing correctly the operation and safety of bridges. Therefore, this paper proposes an integrated load identification system for operating traffic which is based on the characteristics of a steel truss bridge, i.e. the finite distribution of stress influence lines of suspender and orthotropic steel deck, and employs the BWIM (bridge weigh‐in‐motion) technique to establish the functional relationship between vehicle load and stress history as well as the functional relationship between axle load and stress history.To verify the system, a stress monitoring case study was carried out on two steel truss bridges under both controlled and normal traffic conditions. In the case of controlled traffic, monitored information is used to back‐calculate vehicle load and axle load. The load information is then compared with a synchronous video recording of the traffic to check back‐calculated data about vehicle weight, vehicle speed, wheel weight and the deviation between lateral distribution and actual condition, coupling the relationship between vehicle load and corresponding axle load in order to assure the validity of the identification system established. In the case of normal traffic, monitored stress data are used to back‐calculate vehicle load, axle load, vehicle speed and wheel lateral distribution, which are further analysed to work out a probability distribution so that it can directly help assess the real load capacity and fatigue life of the bridges.
Estimating snow water equivalent from GPS vertical site‐position observations in the western United States
Authors: Ouellette Karli J. , de Linage Caroline , Famiglietti James S. 
Published: March 2013

Key Points
Seasonal land surface deformation is observed in the Western U.S.
Crustal loading by the snowpack dominates the observed seasonal deformation
GPS observations may be inverted to estimate snow water equivalent
Toward the virtual stomach: progress in multiscale modeling of gastric electrophysiology and motility
Authors: Du Peng , O'Grady Gregory , Gao Jerry , Sathar Shameer , Cheng Leo K. 
Published: March 2013

AbstractExperimental progress in investigating normal and disordered gastric motility is increasingly being complimented by sophisticated multiscale modeling studies. Mathematical modeling has become a valuable tool in this effort, as there is an ever‐increasing need to gain an integrative and quantitative understanding of how physiological mechanisms achieve coordinated functions across multiple biophysical scales. These interdisciplinary efforts have been particularly notable in the area of gastric electrophysiology, where they are beginning to yield a comprehensive and integrated in silico organ modeling framework, or ‘virtual stomach’. At the cellular level, a number of biophysically based mathematical cell models have been developed, and these are now being applied in areas including investigations of gastric electrical pacemaker mechanisms, smooth muscle electrophysiology, and electromechanical coupling. At the tissue level, micro‐structural models are being creatively developed and employed to investigate clinically significant questions, such as the functional effects of ICC degradation on gastrointestinal (GI) electrical activation. At the organ level, high‐resolution electrical mapping and modeling studies are combined to provide improved insights into normal and dysrhythmic gastric electrical activation. These efforts are also enabling detailed forward and inverse modeling studies at the ‘whole body’ level, with implications for diagnostic techniques for gastric dysrhythmias. These recent advances, together with several others highlighted in this review, collectively demonstrate a powerful trend toward applying mathematical models to effectively investigate structure–function relationships and overcome multiscale challenges in basic and clinical GI research. WIREs Syst Biol Med 2013, 5:481–493. doi: 10.1002/wsbm.1218This article is categorized under:

Models of Systems Properties and Processes > Cellular Models
Translational, Genomic, and Systems Medicine > Diagnostic Methods
Models of Systems Properties and Processes > Organ, Tissue, and Physiological Models
Synthesis, Magnetism, and Thermostability of a Series of Two‐Dimensional Lanthanide–Nickel Heterometallic Coordination Polymers
Authors: Chen Wen‐Xian , Zhuang Gui‐Lin , Wu Shu‐Ting 
Published: March 2013

AbstractA series of Ln–Ni heterometallic coordination polymers, {[Ln2Ni(MIDA)4(H2O)6](H2O)4} (Ln = La (1), Ce (2), Pr (3), and Nd (4); H2MIDA = N‐methyl‐iminodiacetic acid), were obtained under hydrothermal conditions. Single crystal X‐ray diffraction revealed that they feature two‐dimensional isomorphic frameworks, which could be viewed as the construction by one‐dimensional {Ln}n chain connecting by bridges of [Ni(MIDA)2]2. The magnetic measurements reveal that compounds 2–4 exhibit antiferromagnetic properties. TGA results indicate compounds 1 and 4 have good thermostability with the critical temperature of 375 °C.
Synthesis, Structure, and Properties of a New Calcium(II) Complex of 1,10‐Phenanthroline, 1,2,4,5‐Benzenetetracarboxylic Acid, and a New Precursor to Produce Pure Phase Micro‐crystalline Calcite Particles
Authors: Wu Gang , Zhang Shou‐Quan , Guo Li 
Published: March 2013

AbstractThe self‐assembly of 1, 0‐phenanthroline (phen) and 1,2,4,5‐benzenetetracarboxylic acid(H4btc) with Ca(NO3)2 gives rise to a two‐dimensional network structure coordination polymer, [Ca(phen)(btc)0.5(H2O)] (1), which was characterized by elemental analysis, IR spectroscopy, and single‐crystal X‐ray diffraction. This compound is monoclinic, space group C2/c, with Z = 8 in a unit cell with dimensions a = 21.744(3) Å, b = 10.0151(12) Å, c = 14.7122(17) Å, β = 110.2850(10)°. The structure contains one crystallographic unique CaII atom, one phen coordinated molecule and a half of btc4– anion. The phen molecule acts as a didentate ligand chelating with a CaII atom, whereas the btc4– anion acts as a μ6‐bridge linking six different CaII atoms to form a two‐dimensional network with (4, 4) topological structure. The three dimensional stacking structures are formed by C–H···O hydrogen bonding and π–π interaction. The thermal stability and fluorescent properties of 1 were investigated. Calcite particles are produced by calcination of compound 1 at 580 °C. The obtained calcite was characterized by XRD and SEM analyses.
Synthesis, Structure Characterization, and Optical Properties of the Aluminosilicate Li2Na3AlSi2O8
Authors: Han Shujuan , Pan Shilie , Yang Zhihua , Wang Ying , Zhang Bingbing , Zhang Min , Huang Zhenjun , Dong Lingyun , Yu Hongwei 
Published: March 2013

AbstractThe aluminosilicate Li2Na3AlSi2O8 was crystallized from the Li2CO3–H3BO3 flux system. It crystallizes in the orthorhombic space group Cmca, with cell dimensions a = 14.1045 (19) Å, b = 14.7054 (19) Å, c = 7.0635 (9) Å, and Z = 8. The crystal structure consists of a two‐dimensional infinite layer, which is composed of [Al2Si2O12] groups and [SiO4] tetrahedra. The lithium and sodium atoms filling in the interlayer and intralayer link the layers together and balance the charge. IR spectroscopy and BVS calculations were used to verify the validity of the structure. The calculated band structures and the density of states of Li2Na3AlSi2O8 suggest that its direct gap is 4.28 eV.
Magnesium and Cadmium in Covalently‐Bonded Lonsdaleite Networks: Synthesis, Structure, and Bonding of AETMg2 and SrTCd2 (AE = Ca, Sr; T = Pd, Ag, Pt, Au)
Authors: Kersting Marcel , Johnscher Michael , Matar Samir F. , Pöttgen Rainer 
Published: March 2013

AbstractThe alkaline earth metal compounds AETMg2 and AETCd2 (AE = Ca, Sr; T = Pd, Ag, Pt, Au) were synthesized by induction‐melting (or in muffle furnaces) of the elements in sealed niobium ampoules. The new phases were characterized by powder X‐ray diffraction. The structures of SrPdMg2 and SrPdCd2 were investigated by X‐ray diffraction on single crystals: MgCuAl2 type, Cmcm, a = 436.42(4), b = 1130.1(1), c = 820.54(7) pm, wR2 = 0.0115, 511 F2 values for SrPdMg2 and a = 443.5(2), b = 1063.0(2), c = 810.2(2) pm, wR2 = 0.0296, 386 F2 values for SrPdCd2 with 16 variables for each refinement. The magnesium and cadmium atoms build up [TMg2] and [TCd2] polyanionic networks, which leave cavities for the calcium and strontium atoms. The bonding variations within the polyanions, which are mainly influenced by the length of the b axis are discussed. Ab initio calculations of electronic structure, charge densities, and chemical bonding, characterize SrPdMg2 with a larger cohesive energy than SrPdCd2. This is illustrated by larger bonding Pd–Mg interactions, opposite to compensating Pd–Cd between bonding and antibonding states.
Local Structure of Nanoscopic Magnesium Hydroxide ­Fluorides Studied by Natural Abundance 25Mg Solid State NMR Spectroscopy
Authors: Scholz Gudrun , Heidemann Detlef , Kemnitz Erhard 
Published: March 2013

AbstractAlong with X‐ray diffraction measurements, 25Mg solid state NMR experiments were performed in natural abundance at 9.4 T on crystalline and mechanically milled samples of MgO, Mg(OH)2, MgF2, and magnesium hydroxide fluorides Mg(OH)xF2–x prepared on mechanochemical and sol‐gel syntheses routes. In addition to single pulse and spin‐echo sequences, both static 1H‐25Mg CP and 19F‐25Mg CP measurements allowed the registration of 25Mg spectra in attractive short measurement times. Although an assignment of different magnesium species in magnesium hydroxide fluorides is only hardly possible, position and line shapes of 25Mg spectra of magnesium hydroxide fluorides reflect chemically reliable trends. All samples studied here show a sixfold fluorine, oxygen, or mixed fluorine / oxygen coordination of magnesium, also in highly disordered samples.
Magnesiation of N‐Methyl‐1, 3‐propylenediaminoboryl Ferrocene
Authors: Reichert Adelina , Schmidt Jurema , Bolte Michael , Wagner Matthias , Lerner Hans‐Wolfram 
Published: March 2013

AbstractN‐methyl‐1, 3‐propylenediaminoboryl ferrocene (1‐H) was obtained by a three‐step synthesis: i) At first ferrocene was reacted with BBr3 to give dibromoboryl ferrocene (FcBBr2). ii) In a second step FcBBr2 was transformed into FcB(OMe)2 by treatment of FcBBr2 with Me3SiOMe. iii) Finally reaction of FcB(OMe)2 with H2NCH2CH2CH2NMeH yielded the boryl ferrocene 1‐H. In addition we examined the metalation of 1‐H with magnesium 2, 2, 6, 6‐tetramethylpiperidide (TMP) and mixtures of Li(TMP)/Mg(TMP)2. The reaction of 1‐H with 0.5 equivalent of Mg(TMP)2 yielded quantitatively the homoleptic complex Mg[1]2 whereas metalation of 1‐H with 1.5 and 2 equivalents of Mg(TMP)2 gave product mixtures. However, N,N'‐dimethyl‐1, 3‐propylenediaminoboryl ferrocene (1‐Me) and the ortho‐methylated derivatives 2‐Me and 3‐Me (3‐Me bears additionally one Me group in 1′‐postion) could be identified after derivatization with Me2SO4. The metalated ferrocene derivative (Li2(THP)2Mg3(TMP)2[3]2) which is bearing one Li and one Mg atom in the ortho‐position and a further two Mg atoms in N‐ and 1′‐positions, was formed in good yield by treatment of 1‐H with an excess of a 1:2 mixture of Li(TMP) and Mg(TMP)2 in tetrahydropyran (THP). Single crystals of the racemic complex Li2(THP)2Mg3(TMP)2[3]2 were available by gas‐phase diffusion of hexane into a concentrated THP solution at ambient temperature (space group C2/c). The crystal structure of Li2(THP)2Mg3(TMP)2[3]2 displays a racemic dimer of the Rp‐ and the Sp‐enantiomer.