bluuebunny/crossref_metadata_2025_split huggingface dataset:
Guidelines for the Management of Patients With Unruptured Intracranial Aneurysms
Authors: Thompson B. Gregory , Brown Robert D. , Amin-Hanjani Sepideh , Broderick Joseph P. , Cockroft Kevin M. , Connolly E. Sander , Duckwiler Gary R. , Harris Catherine C. , Howard Virginia J. , Johnston S. Claiborne (Clay) , Meyers Philip M. , Molyneux Andrew , Ogilvy Christopher S. , Ringer Andrew J. , Torner James 
Published: June 2015

Purpose—
The aim of this updated statement is to provide comprehensive and evidence-based recommendations for management of patients with unruptured intracranial aneurysms.

Methods—
Writing group members used systematic literature reviews from January 1977 up to June 2014. They also reviewed contemporary published evidence-based guidelines, personal files, and published expert opinion to summarize existing evidence, indicate gaps in current knowledge, and when appropriate, formulated recommendations using standard American Heart Association criteria. The guideline underwent extensive peer review, including review by the Stroke Council Leadership and Stroke Scientific Statement Oversight Committees, before consideration and approval by the American Heart Association Science Advisory and Coordinating Committee.

Results—
Evidence-based guidelines are presented for the care of patients presenting with unruptured intracranial aneurysms. The guidelines address presentation, natural history, epidemiology, risk factors, screening, diagnosis, imaging and outcomes from surgical and endovascular treatment.
Stroke Legislation Impacts Distribution of Certified Stroke Centers in the United States
Authors: Uchino Ken , Man Shumei , Schold Jesse D. , Katzan Irene L. 
Published: June 2015

Background and Purpose—
The number of certified primary stroke centers (PSCs) have increased dramatically during the past decade in the United States We aimed to understand the factors affecting PSC distribution in the United States, including the impact of state stroke legislation.

Methods—
PSCs certified by national organization or state until December 2013 were searched from available databases. The proportion of PSC among short-term general hospitals in each state was calculated and factors affecting its distribution were analyzed.

Results—

By the end of 2013, the proportion of PSC varied from 4% to 100% among the 50 states and District of Columbia. The 18 states that had legislation in designating stroke centers and regulating stroke triage had higher PSC percentages (median, 43%; range, 13%–100%) than the remaining states (median, 13%; range, 4%–75%;
P
<0.001). State stroke legislation, urbanization, state economic output, and larger hospital size independently increased the likelihood of a hospital to be stroke certified. From 2009 to 2013, states with stroke legislation had greater increase of PSC percentages when compared with the states without legislation (median increase, 16% versus 6%;
P
=0.0067). Among the 1505 stroke centers, 74% were certified by the Joint Commission, 20% by state, and 6% by other organizations. Stroke centers certified only by state were smaller in size by hospital bed count compared with those certified by the Joint Commission (
P
<0.001).

Conclusions—
State stroke legislation, a generalizable intervention, increased the number of certified stroke centers in the United States, potentially improving accessibility of standardized care for patients with acute ischemic stroke.
Ацэначныя дзеясловы як моўнае адлюстраванне агульнапрынятых уяўленняў аб паняццях "норма" – "не-норма"
Authors: Маліцкі [Malitski] Юрый [IUryĭ] 
Published: June 2015

Evaluative verbs as a linguistic reflection of generally accepted ideas about the concepts of “norm” – “not-the-norm”The article is focused on analysis of evaluative verbs in modern Belorussian literary language. The subject of the study are oral speech verbs. Evaluative verbal nominations considered as a reflection of generally accepted ideas about the concepts “norm” – “not-the-norm”. A description of semantical and formal features of these nominations is given. Czasowniki oceniające jako językowe odzwierciedlenie ogólnie przyjętych wyobrażeń o pojęciach „norma" - „nie-norma"W artykule opisane zostały na materiale współczesnego literackiego języka białoruskiego oceniające czasowniki mówienia. Znaczeniowo-pragmatyczne właściwości tych wyrazów autor rozpatruje jako odzwierciedlenie w języku tradycyjnych wyobrażeń o pojęciach „norma” – „nie-norma”. W artykule omówione zostały podstawowe treści emocjonalnooceniające wyrażane przez te czasowniki.
Światowa slawistyka w Warszawie. Sprawozdanie z konferencji
Authors: Jawor Anna , Dołowy-Rybińska Nicole 
Published: June 2015

World Slavic studies in Warsaw. Conference reportThe text is a report from the international conference, ‘The Identity of the Slavs past and present: language, culture, literature in young Slavists’ research’ (May 2014). The conference was organized by the Institute of Slavic Studies, the Polish Academy of Sciences, the Institute of Western and Southern Slavic Studies, Warsaw University and the Slavic Foundation. The aim of the conference was to confront the research carried out by young researchers from Poland and Slavic countries with those conducted by their colleagues from Western Europe. These researches were compared with the Slavic studies carried out in the world. Światowa slawistyka w Warszawie. Sprawozdanie z konferencji Tekst jest sprawozdaniem z międzynarodowej konferencji naukowej „Tożsamość Słowian dawniej i dziś: język, kultura, literatura w badaniach młodych slawistów” (maj 2014). Konferencja została zorganizowana przez Instytut Slawistyki Polskiej Akademii Nauk, Instytut Slawistyki Zachodniej i Południowej Uniwersytetu Warszawskiego i Fundację Slawistyczną. Jej celem było skonfrontowanie badań prowadzonych przez młodych naukowców z Polski i krajów słowiańskich z badaniami prowadzonymi przez ich kolegów z krajów Europy Zachodniej oraz porównanie ich z dominującymi tendencjami slawistyk światowych.
The Impact of Arctic Winter Infrared Radiation on Early Summer Sea Ice
Authors: Park Hyo-Seok , Lee Sukyoung , Kosaka Yu , Son Seok-Woo , Kim Sang-Woo 
Published: June 2015

Abstract
The Arctic summer sea ice area has been rapidly decreasing in recent decades. In addition to this trend, substantial interannual variability is present, as is highlighted by the recovery in sea ice area in 2013 following the record minimum in 2012. This interannual variability of the Arctic summer sea ice area has been attributed to the springtime weather disturbances. Here, by utilizing reanalysis- and satellite-based sea ice data, this study shows that summers with unusually small sea ice area are preceded by winters with anomalously strong downward longwave radiation over the Eurasian sector of the Arctic Ocean. This anomalous wintertime radiative forcing at the surface is up to 10–15 W m−2, which is about twice as strong than that during the spring. During the same winters, the poleward moisture and warm-air intrusions into the Eurasian sector of the Arctic Ocean are anomalously strong and the resulting moisture convergence field closely resembles positive anomalies in column-integrated water vapor and tropospheric temperature.
Climate model simulations support the above-mentioned findings and further show that the anomalously strong wintertime radiative forcing can decrease sea ice thickness over wide areas of the Arctic Ocean, especially over the Eurasian sector. During the winters preceding the anomalously small summer sea ice area, the upper ocean of the model is anomalously warm over the Barents Sea, indicating that the upper-ocean heat content contributes to winter sea ice thinning. Finally, mass divergence by ice drift in the preceding winter and spring contributes to the thinning of sea ice over the East Siberian and Chukchi Seas, where radiative forcing and upper-ocean heat content anomalies are relatively weak.
The birth of morality and the Fall of Adam through an evolutionary inter-species lens
Authors: Deane-Drummond Celia 
Published: June 2015

I begin by suggesting that the Christian metanarrative about the Fall of Adam has overreached its confines in Christian theology, becoming a leitmotif in Western culture more broadly. While sympathetic to aspects of Wentzel van Huyssteen’s post-foundationalist approach to the evolution of morality, I argue that a reinterpretation of the Fall through an evolutionary inter-species lens takes proper account of cultural attachment to the Fall narrative, but breaks it open theologically in radically new ways. In particular, I suggest that the Fall marks a theo-dramatic transition to the propensity for sainthood or sin that is highly distinctive for human beings, but one that is also conducted in the context of a community of others, including other animals. These creaturely others are not anonymous, but show up their own distinctive agency and virtue (and sometimes vice) in ways that intersect and overlap with moral capabilities emerging in the earliest hominin communities. Drawing on biblical exegesis of Genesis 2 and recent and ongoing anthropological research, I will use inter-species illustrations from contemporary contexts, including human–elephant, human–hyena and human–puma affiliations. I argue that a shift from an individualistic to a wider community understanding of human morality is crucially important, not just for theoretical discussions about the evolution of morality, but also in envisaging the meaning of human personhood and the theological ground for moral action.
Sources of meaning derived from occupational engagement for people recovering from mental illness
Authors: Hancock Nicola , Honey Anne , Bundy Anita C 
Published: June 2015

Introduction Engagement in meaningful occupations is of central importance in mental health recovery. The purpose of this study was to gain a richer understanding of the relationships between occupations, sources of meaning and recovery for people living with mental illness. Method People living with mental illness ( n = 78) attending an Australian Clubhouse completed the recovery assessment scale and socially valued role classification scale. Qualitative and quantitative data were analysed using mixed methods. Findings The most meaningful occupations were those most likely to provide opportunities for social connection and being valued by others. The frequency with which these socially derived sources of meaning were identified far outweighed other sources: positive sense of self; skills/personal development; time use/routine; financial gain and fun/pleasure. Neither the occupations identified as most meaningful nor the source of meaning differed depending on level of recovery. Conclusion Irrespective of stage of recovery, socially derived aspects of meaning are most frequently prioritized by people living with mental illness. In facilitating engagement in personally meaningful occupations, occupational therapists need to understand that, for many, meaningfulness centres around inter-dependence: being with others, belonging, giving or contributing and being valued by others.
Solving the Supply Shortage at ICC India
Authors: Mukherjee Jaydeep 
Published: June 2015

International Color Company (ICC), a multinational paint major was an established player in the paint market in India. It had launched its premium 2-pack refinish product range in January 2013. Within first six months of the launch, when the excitement of the new launch had abated, it was found that there were shortage of certain SKU’s. There were incidences of shortage in some specific locations as well as the entire country, which required to be addressed on an immediate basis. The import lead time was 12 weeks by ship and 4 weeks by air which made the solution even more difficult. The situation was becoming more acute every passing day. Jayant, the Product Manager responsible for 2-pack refinish product range had been given two months time by the top management of ICC to get the situation under control. Apart from the mismatches in stock availability and its requirements across the retail outlets and branches, Jayant had inherited problems which were related to the structure and compensation plan of ICC, which made his task even more challenging.
Effects of ketamine and alfaxalone on application of a feline pain assessment scale
Authors: Buisman Mandy , Wagner Marika C , Hasiuk Michelle MM , Prebble Melanie , Law Laura , Pang Daniel SJ 
Published: June 2015

Objectives The objective of this study was to compare the effects of ketamine and alfaxalone on the application of a validated feline-specific multidimensional composite pain scale (UNESP-Botucatu MCPS). Methods In a prospective, randomized, blinded, crossover trial, 11 adult cats (weight 4.4 ± 0.6 kg) were given dexmedetomidine (15 μg/kg) and hydromorphone (0.05 mg/kg) with either alfaxalone (2 mg/kg) or ketamine (5 mg/kg) as a single intramuscular injection for the induction of general anesthesia. After orotracheal intubation, general anesthesia (without surgery) was maintained for 32 mins with isoflurane, followed by atipamezole. The following parameters were recorded at baseline, 1–8 h and 24 h post-extubation: pain (pain expression and psychomotor subscales) and sedation scale scores. Alfaxalone treatment injection sites were examined for inflammation at baseline, postinjection, and 8 h and 24 h post-extubation. Results Psychomotor scores were higher with ketamine at hours 1 (3.5 [0–5.0], P <0.0001), 2 (2.5 [0–4.0], P <0.0001) and 3 (0.5 [0–4.0], P = 0.009) post-extubation compared with alfaxalone (hour 1, 0 [0–2]; hour 2, 0 [0–0]; hour 3, 0 [0–0]). Six cats in the ketamine group crossed the analgesic intervention threshold. In contrast, pain expression scores did not differ significantly between treatments at any time ( P >0.05); one cat from each group crossed the analgesic intervention threshold. Sedation was greater with ketamine (1 [0–3], P = 0.02) than alfaxalone (0 [0–1]) 1 h post-extubation. No cats had visible inflammation at the injection sites at any time. Conclusions and relevance Ketamine has a confounding effect on the psychomotor subscale of the pain scale studied, which may lead to erroneous administration of rescue analgesia. In contrast, alfaxalone was not associated with significant increases in either pain subscale. These effects of ketamine should be considered when evaluating acute postoperative pain in cats.
Plerixafor+G-CSF–mobilized CD34+ cells represent an optimal graft source for thalassemia gene therapy
Authors: Karponi Garyfalia , Psatha Nikoletta , Lederer Carsten Werner , Adair Jennifer Eileen , Zervou Fani , Zogas Nikolaos , Kleanthous Marina , Tsatalas Constantinos , Anagnostopoulos Achilles , Sadelain Michel , Rivière Isabelle , Stamatoyannopoulos George , Yannaki Evangelia 
Published: June 2015

Key Points
Effective gene correction and long-term engraftment of human thalassemic CD34+ cells mobilized with different strategies. Plerixafor+G-CSF–mobilized CD34+ cells produce higher β-globin/VCN and superior early engraftment over single agent-mobilized cells.
Critical analysis of the stringent complete response in multiple myeloma: contribution of sFLC and bone marrow clonality
Authors: Martínez-López Joaquín , Paiva Bruno , López-Anglada Lucía , Mateos María-Victoria , Cedena Teresa , Vidríales María-Belén , Sáez-Gómez María Auxiliadora , Contreras Teresa , Oriol Albert , Rapado Inmaculada , Teruel Ana-Isabel , Cordón Lourdes , Blanchard María Jesús , Bengoechea Enrique , Palomera Luis , de Arriba Felipe , Cueto-Felgueroso Cecilia , Orfao Alberto , Bladé Joan , San Miguel Jesús F. , Lahuerta Juan José 
Published: June 2015

Key Points
In MM patients, stringent CR criteria, in particular the sFLC ratio, do not predict significantly better outcome among MM patients in conventional CR.
Treatment of Acanthamoeba neurotrophic corneal ulcer with topical matrix therapy
Authors: Mateo Antonio , Abadía Beatriz , Calvo Pilar , Minguez Enrique , Pablo Luis , del Castillo José Manuel Benitez 
Published: June 2015

Abstract

Background
This study was done to evaluate the visual and anatomical outcomes of topical regenerating agents as a novel therapy for neutrophic corneal ulcer (NCU) secondary to acanthamoeba infection.

Findings
A 20-year-old woman with a history of contact lens wear was referred to our hospital for keratitis after responding poorly to conventional treatment. In vivo confocal microscopy images suggested acanthamoeba keratitis with double-walled cysts in the anterior corneal stroma. Acanthamoeba infection was confirmed by laboratory findings. She was started on 0.1 % propamidine and 0.02 % chlorhexidine drops every hour. The antibiotic and antifungal drops were stopped when bacterial and fungal cultures proved negative. A central neurotrophic corneal ulcers (NCU) appeared, and despite treatment with artificial tears, bandage contact lens, and autologous serum, the ulcer worsened and she was treated with topical CACICOL20 (1 drop every 2 days) for 8 weeks. The corneal defect was completely repaired in 3 weeks. The treatment was well tolerated, and no local or systemic side effects were noted. Visual acuity remained 20/400. Two months later, the defect was still closed and the patient continued with 0.1 % propamidine and 0.02 % chlorhexidine drops, bandage contact lens, artificial tears, and autologous serum.

Conclusions
Topical regenerating agents interact with components of the extracellular matrix, binding matrix proteins and protecting them from proteolysis, restoring the matrix environment, and improving tissue healing. In this case, CALCICOL20 was effective for vision stabilization, wound healing, and was well tolerated for NCU secondary to acanthamoeba infection.
Further studies on the biological activity of hazelnut allergens
Authors: Blanc F. , Bernard H. , Ah‐Leung S. , Przybylski‐Nicaise L. , Skov P. Stahl , Purohit A. , de Blay F. , Ballmer‐Weber B. , Fritsche P. , Rivas M. Fernandez , Reig I. , Sinaniotis A. , Vassilopoulou E. , Hoffmann‐Sommergruber K. , Vieths S. , Rigby N. , Mills C. , Adel‐Patient K. 
Published: June 2015

AbstractBackgroundSensitization to hazelnut allergens vary depending on the geographic origin and age of the patients. The objective of this study was to further investigate the allergenic activity of hazelnut allergens using sera from patients recruited in various European regions and presenting different sensitization patterns to hazelnut proteins.MethodsNatural Cor a 11 and Cor a 9 were purified from hazelnut whereas Cor a 1 and Cor a 8 were produced as recombinant proteins (rCor a 1.04 and rCor a 8). Sera from hazelnut allergic patients were collected in France (n = 5), Switzerland (n = 2), Greece (n = 11) and Spain (n = 3), within the Europrevall project. Total and allergen‐specific IgE were quantified by enzyme allergosorbent test and IgE immunoblot were performed using pooled sera from birch‐pollen endemic region or from Greece. Histamine Release (HR) assays were performed with stripped basophils passively sensitized with individual sera and challenged by a hazelnut extract or the different hazelnut allergens.ResultsAs previously described, hazelnut allergic patients from Mediterranean countries are mainly sensitized to the nsLTP Cor a 8 whereas patients from France and Switzerland are sensitized to pollen‐related allergens. Interestingly, an intermediate profile was evidenced in patients from Madrid. Hazelnut 7S globulin (Cor a 11) and 11S globulin (Cor a 9) were found to be minor allergens, recognized only by patients from Mediterranean countries. The biologic activity of the 4 tested allergens, analysed by HR assay, further confirmed the sensitization patterns, but also demonstrated the very high elicitation potency of Cor a 8.ConclusionsThis work, extending previously published researches, represents a step towards the better understanding of the complexity of hazelnut allergy and provides new data on the biological activity of hazelnut allergens and extracts.
Exploring soybean metabolic pathways based on probabilistic graphical model and knowledge-based methods
Authors: Hou Jie , Stacey Gary , Cheng Jianlin 
Published: June 2015

Abstract
Soybean (Glycine max) is a major source of vegetable oil and protein for both animal and human consumption. The completion of soybean genome sequence led to a number of transcriptomic studies (RNA-seq), which provide a resource for gene discovery and functional analysis. Several data-driven (e.g., based on gene expression data) and knowledge-based (e.g., predictions of molecular interactions) methods have been proposed and implemented. In order to better understand gene relationships and protein interactions, we applied probabilistic graphical methods, based on Bayesian network and knowledgebase constraints using gene expression data to reconstruct soybean metabolic pathways. The results show that this method can predict new relationships between genes, improving on traditional reference pathway maps.
Immunoglobulin G4-related diseases in the head and neck: A systematic review
Authors: Mulholland Graeme B. , Jeffery Caroline C. , Satija Paras , Côté David W. J. 
Published: June 2015

Background Immunoglobulin G4 related disease (IgG4-RD) is a poorly understood chronic inflammatory disorder affecting the middle-aged and elderly that can present to the otolaryngologist. We aim to summarize the current literature regarding the manifestations and management of IgG4-RD in the head and neck. Methods Pubmed and EMBASE were searched using the term relevant search algorithm utilizing keywords such as: IgG4 related disease, head and neck, orbit, salivary glands, sialadenitis, Kuttner, angiocentric eosinophilic fibrosis, submandibular, lacrimal, thyroid, dacryoadenitis, nasal, sinus, and Mikulicz's. Reference lists were searched for identification of relevant studies. Case reports, original research and review articles published in English from 1964 to 2014 whose major topic was IgG4-RD affecting the head and neck were included. Data regarding patient demographics, presentation, histopathology, management and treatment outcomes of IgG4-RD were extracted. Level of evidence was also assessed and data were pooled where possible. Three independent reviewers screened eligible studies; extracted relevant data and discrepancies were resolved by consensus, where applicable. Descriptive and comparative statistics were performed. Results Fourty-three articles met our inclusion criteria. IgG4-RD most often presents as a mass lesion in the head and neck region. Common diagnostic features include: 1) elevated serum IgG4 level, 2) marked infiltration of exocrine glands by IgG4-positive plasma cells with fibrosis, and 3) marked improvement with corticosteroid therapy and additional immunosuppressive therapy in corticosteroid refractory cases. Early diagnosis and involvement of rheumatology is important in management. Conclusions IgG4-RD is a challenging non-surgical disease that has multiple manifestations in the head and neck. It must be distinguished from various mimics including malignancy, systemic diseases, and infectious. Otolaryngology-Head and Neck surgeons should be aware of this condition and its management.
Effect of Water Added into Acetonitrile Solvent on Oxidation of Benzene with Hydrogen Peroxide over Iron Complexes Encapsulated in Zeolite
Authors: Yamaguchi Syuhei , Ohnishi Tetsuya , Miyake Yuki , Yahiro Hidenori 
Published: June 2015

Abstract
Catalytic activity of iron complex-encapsulated zeolite catalyst ([Fe(bpy)3]2+@Y) for oxidation of benzene increased with increasing the amount of water added to acetonitrile. Maximum value of catalytic activity was obtained when the volume ratio of the solvents was equal (CH3CN:H2O = 1:1). After reaction at 24 h, the turnover number of [Fe(bpy)3]2+@Y was higher than that of [Fe(bpy)3](ClO4)2 as a homogeneous catalyst.