bluuebunny/crossref_metadata_2025_split huggingface dataset:
Oxidative Desulfurization of Diesel Oil Using Mesoporous Phosphotungstic Acid/SiO2 as Catalyst
Authors: Yan Xue‐Min , Lei Jia‐Heng , Liu Dan , Wu Yang‐Chun , Guo Li‐Ping 
Published: May 2015

AbstractOrdered mesoporous phosphotungstic acid/SiO2 (HPW/SiO2) with Keggin‐type heteropolyacids (HPAs) encapsulated into a SiO2 framework has been synthesized and used as the catalyst for oxidative desulfurization of diesel fuel. The sulfur compounds in diesel were oxidized and removed at a temperature range of 50–80 °C with H2O2 as the oxidant and acetonitrile as the extraction agent. The sulfur content in diesel was reduced to as low as 48–86 μg/g from the initial level of 438 μg/g. The loss in catalytic activity was negligible even after five cycles of use, and the reduction of the sulfur content was enhanced with increasing the immobilized phosphotungstic acid (HPW) concentration. Oxidation of model compounds showed that in the heterogeneous system both the electron density and the steric hindrance affected the reactivity of these sulfur compounds. The reactivities of these sulfur compounds studied in this work followed the order of dibenzothiophene > 4,6‐dimethydibenzothiophene > benzothiophene.
Kinetic Spectrofluorometric Determination of Thioctic Acid in Bulk and Pharmaceutical Preparations via its Oxidation with Cerium(IV)
Authors: Ibrahim F. A. , Ali F. A. , Ahmed S. M. , Tolba M. M. 
Published: May 2015

AbstractA highly simple and sensitive kinetic spectrofluorometric method was developed for the determination of thioctic acid. The method is based on the oxidation of the studied drug with cerium(IV) ammonium sulfate in acidic medium. The fluorescence of the produced Ce(III) was measured at 365 nm after excitation at 255 nm. The different experimental parameters affecting the development and stability of the reaction product were carefully studied and optimized. The method is applicable over the concentration range of 0.02 to 0.12 μg/mL with a detection limit of 6.06 × 10−3 μg/mL and a quantification limit of 0.02 μg/mL. The method was successfully applied for the assay of the studied drug in pharmaceutical formulations. The results obtained were in good agreement with those obtained with the reference method.
Potentiometric and Spectrophotometric Studies of Copper(II) Complexes of Some Ligands in Aqueous and Nonaqueous Solution
Authors: Shokrollahi Ardeshir , Ghaedi Mehrorang , Ghaedi Hamed 
Published: May 2015

AbstractStoichiometry and equilibrium study of copper‐ligands including mercaptobenzoxazole (MBO), 4‐propyl 2‐thiouracyl (PTU), methyl‐2‐pyridylketone oxime (MPKO), phenyl‐2‐pyridylketone oxime (PPKO), 4,6‐dihydroxy‐2‐mercaptopyrimidine (DHMP), N,N′‐phenylene bis(salicylaldimine) (PBS) and 1,2‐bis(2‐hydroxyphenyl)naphtaldiimine (BHNPDI) were conducted in aqueous and nonaqueous solution by potentiometry and spectrophotometry. Stability constants of the complexes are determined at 25 ± 1 °C and 0.1 or 0.05 M ionic strength in water or acetonitrile solvents. Oximes ligand protonation constants and copper‐ligands complexes' stability and hydrolysis constants were calculated using the BEST program in aqueous solution. The stability constants of copper‐ligands complexes were calculated using the KINFIT program in acetonitrile solution. The results of these two methods are made self‐consistent, then rationalized assuming an equilibrium model including the species, ML, MLH, MLOH and ML2 (where the charges of the species have been ignored for the sake of simplicity) (L = MBO, PTU, MPKO, PPKO, DHMP, BHNPDI and PBS).
Sensitive Determination of Nanogram Levels of Diacerein in a Pharmaceutical Formulation by Flow Injection Chemiluminescence Analysis
Authors: Yao Han‐Chun , Yang Xiao‐Feng , Li Hua 
Published: May 2015

AbstractA simple, sensitive and inexpensive flow injection chemiluminescence (FI‐CL) method for the determination of diacerein was proposed. It was based on the greatly enhancive effect of diacerein on the CL reaction between luminol and hydrogen peroxide in alkaline medium. The enhanced CL intensity was linear with the concentration of diacerein over the range 1.0–500 ng/mL with a detection limit (3σ) of 0.2 ng/mL. The relative standard deviation was 1.1% (n = 8, 20 ng/mL diacerein) and the sample throughput was about 120 samples h−1. This simple method has been successfully applied for the determination of diacerein in a pharmaceutical formulation without interference from its potential impurities. The degradation of diacerein was also investigated briefly.
N‐Bromosuccinimide (NBS): A Mild and Efficient Catalyst for Tetrahydropyranylation of Alcohols and Phenols under Solvent‐Free Conditions
Authors: Khazaei Ardeshir , Rostami Amin , Raiatzadeh Ayeh 
Published: May 2015

AbstractDifferent types of alcohols and phenols are tetrahydropyranylated in the presence of NBS catalyst in good to excellent yields under mild, neutral and solvent‐free conditions.
Synthesis and Reactions of Naphtho[1′,2′:4,5]Furo[3,2‐b]Pyridine and Naphtho[1′,2′:4,5]Furo[3,2‐d]Pyrimidine Derivatives
Authors: Badr M. Z. A. , Kamal El‐Dean A. M. , Moustafa O. S. , Zaki R. M. 
Published: May 2015

Abstract2‐Acyl‐3‐aminonaphtho[2,1‐b]furan (1) reacts with activated methylene such as malono nitrile or ethyl cyanoacetate to afford naphtho[1′,2′:4,5]furo[3,2‐b]pyridine 2a,b. Chloroacylation of the amino group in compound (1) gave compound 3 which reacts with different amines to produce compound 4.
5‐(1‐Pyrrolyl)‐2‐Phenylthieno[2,3‐d]Pyrimidine as Building Block in Heterocyclic Synthesis: Novel Synthesis of Some Pyrazoles, Pyrimidines, Imidazo[1,2‐a]Pyrimidines, Pyrazolo[1,5‐a]Pyrimidines, Pyrido‐(Pyrimido)Pyrazolo[1,5‐a]Pyrimidines, 1,2,4‐Triazolo[1,5‐a]Pyrimidine and a 1,2,3,4‐Tetrazolo[1,5‐a]Pyrimidine Derivative
Authors: Ho Yuh‐Wen 
Published: May 2015

AbstractTreatment of enaminone derivative 6‐(3‐dimethylamino‐acryloyl)‐5‐(1‐pyrrolyl)‐4‐methyl‐2‐phenylthieno[2,3‐d]pyrimidine 1 with appropriate hydrazine compounds 2a,b in refluxing ethanol afforded the corresponding 6‐(1‐substituted‐pyrazol‐5‐yl)‐2‐phenylthieno[2,3‐d]pyrimidines 3a,b. Cyclization of enaminone derivative 1 with appropriate guanidine compounds 13a‐c in the presence of a basic catalyst yields the corresponding 6‐(2‐substituted‐pyrmidin‐6‐yl)‐2‐phenylthieno[2,3‐d]pyrimidines 15a‐c. The compound 15c can be cyclized with appropriate α‐halogenocarbonyl compounds 16a‐d to afford the corresponding 6‐(2‐substituted‐imidazo[1,2‐a]pyrimidin‐7‐yl)‐2‐phenylthieno[2,3‐d]pyrimidines 17a‐d. On the other hand, the pyrazolo[1,5‐a]pyrimidines 20a‐c, pyrido(pyrimido)[2,3:4,3]pyrazolo[1,5‐a]pyrimidines 22a‐c, pyrido[4,5:4,3]pyrazolo[1,5‐a]pyrimidine 24, 1,2,4‐triazolo[1,5‐a]pyrimidine 26a, and 1,2,3,4‐tetrazolo[1,5‐a]pyrimidine derivative 26b were also obtained by the intramolecular cyclization of enaminone derivative 1 with appropriate 5(3)‐amino‐pyrazole derivatives 18a‐c, 21a‐c, 23, 3‐amino‐1,2,4‐triazole 25a and 5‐amino‐1H‐tetrazole 25b under acid conditions, respectively.
Colorimetric Microdetermination of Bromhexine Drug in Aqueous Solution
Authors: Khalil Rabah A. , Saeed Abdussamed M. A. 
Published: May 2015

AbstractA simple, accurate and sensitive method for determination of bromhexine hydrochloride drug in aqueous solution has been described. The procedure has been based on the reaction of this drug with an excess amount of p‐dimethylaminobenzaldehyde (DAB) in acidic medium (pH =1.6) and the presence of sodium dodecyl sulfate (SDS). The produced yellow color from this reaction has been followed spectrophotometrically at an absorbance maximum of 430 nm. Microgram amounts of bromhexine hydrochloride can be estimated with an accuracy of better than ±1.5% and a relative standard deviation of less than 3.5%. The method has been used for the determination of 0.41–82.5 μg.mL−1 with a molar extinction coefficient of 4699.1–3602.3 L.mol−1.cm−1.An application of the developed procedure to bulk bromhexine hydrochloride and some of its pharmaceutical preparations has been carried out. The effect of the presence of some other surfactants and common pharmaceutical additives has been investigated. A comparison of the presented method with that in the absence of SDS and the standard method of the British Pharmacopoeia has been explored. The suggestion, according to the results, is to use the developed method as standard in pharmaceutical applications.
Electro‐Oxidation of 3,4‐Dihydroxybenzoic Acid in the Presence of 6‐Methyl‐1,2,4‐Triazine‐3‐Thione‐5‐One: Unique Synthesis of 7H‐Thiazolo[3,2‐b]‐1,2,4‐Triazin‐7‐One Derivative in Aqueous Media
Authors: Fotouhi Lida , Nematollahi Davood , Heravi Majid M. 
Published: May 2015

AbstractThe electrochemical oxidation of 3,4‐dihydroxy benzoic acid (1) has been studied in the presence of 6‐methyl‐1,2,4‐triazine‐3‐thione‐5‐one (2) in aqueous solution. The oxidation mechanism of 1 and its reaction in the presence of 2 was offered. It was confirmed that 1 is converted to 7H‐thiazolo[3,2‐b]‐1,2,4‐triazin‐7‐one derivative 5 through Michael addition reaction of 2 to anodically generated o‐benzoquinone. The results of the research were used for electrochemical synthesis of 5 in an undivided cell in good yield and purity.
The Direct Electron Transfer of Iron‐Containing Superoxide Dismutase (Fe‐SOD) and its Catalysis for the Oxygen Reduction Reaction (ORR) in Room Temperature Ionic Liquids (RTILs) on a Gold Electrode
Authors: Ding Ke‐Qiang 
Published: May 2015

AbstractIn this work, for the first time, the direct electron transfer of iron‐containing superoxide dismutase (Fe‐SOD) was observed by cyclic voltammetry on a gold (Au) electrode in three RTILs, i.e., 1‐ethyl‐3‐methylimidazolium tetrafluoroborate (EMIBF4), 1‐n‐propyl‐3‐methylimidazolium tetrafluoroborate (PMIBF4) and 1‐n‐butyl‐3‐methylimidazolium tetrafluoroborate (BMIBF4). And the results demonstrate that when the scan rate was as low as 1 mV/s, a pair of well‐defined quasi‐reversible peaks of Fe‐SOD was presented, while as the potential scan rate was above 10 mV/s, the reduction peak of Fe‐SOD disappeared though its oxidation peak could be clearly observed even as the potential scan rate was up to 400 mV/s, strongly indicating that these CVs we observed were attributable to Fe‐SOD rather than the impurities in RTILs. Its catalysis for oxygen reduction reaction (ORR) was directly verified by the shifting of formal potential, E0′, of ORR, to the positive direction though the value of standard rate constant, κ0, corresponding to ORR, was not much enhanced. In PMIBF4, for the multi‐walled carbon nanotubes (MWCNTs)‐modified gold electrode, both the reduction peak current and oxidation peak current for oxygen redox reaction were all dramatically enhanced compared to the case of a bare gold electrode, and the value of κ0 was also increased from 3.1 × 10−3 cm s−1 for the bare gold electrode, to 17.5 × 10−3 cm s−1. Hence, in the presence of Fe‐SOD in RTILs, MWCNTs, showing catalysis for the electron transfer process of ORR, coupled with Fe‐SOD, leading to the shifting of formal potential corresponding to ORR to the positive direction, presented us a satisfactory catalysis for ORR in RTILs. Some reasons available for this catalysis behavior stemming from Fe‐SOD, and MWCNTs as well, for ORR are discussed based on the previously developed proposition.
Gold(I) ‐Nickel(II)‐4,4′‐bpy‐Phosphine Complexes: Synthesis and Multinuclear NMR Study
Authors: Byabartta Prithwiraj , Laguna Mariano 
Published: May 2015

AbstractSilver triflate [AgOTf] assisted de‐bromination gives [Ni(dppm/dppe/(PPh3)2) (OTf)2], which on reaction with 4,4′‐bpy and gold(I) phosphines in dichloromethane medium by the self assemble technique leads to [{(L)Ni}{(4,4‐bpy)Au(PPh3)}2](OTf)4, (1,2,3) [{(L)Ni(4,4‐bpy)}4](OTf)8, (4,5,6) [L = dppm/dppe/(PPh3)2 = diphenyl phosphino‐methane, ‐ethane, bis‐triphenylphosphine, OSO2CF3 is the triflate anion]. The maximum molecular peak of the corresponding molecule is observed in the ESI mass spectrum. Ir spectra of the complexes show ‐C=C‐, ‐C=N‐, as well as phosphine stretching. The 1H NMR spectra as well as 31P (1H)NMR suggest solution stereochemistry, proton movement, and phosphorus proton interaction. Considering all the moieties, there are a lot of carbon atoms in the molecule reflected by the 13C NMR spectrum. In the 1H‐1H COSY spectrum of the present complexes and contour peaks in the 1H−13C HMQC spectrum, we assign the solution structure and stereoretentive transformation in each step.
One‐Pot Synthesis of Pyrido[2,3‐d]Pyrimidine‐2‐Thiones and a Study of Their Reactivity Towards Some Reagents
Authors: El‐Gazzar A. B. A. , Hafez H. N. , Yakout E. M. A. 
Published: May 2015

AbstractA series of pyrido[2,3‐d]pyrimidine‐2‐thione derivatives (5a‐c) were synthesized by the one‐pot reaction of the appropriate aldehyde, malononitrile and 6‐aminothiouracil (1) in dimethyl‐formamide. The same compounds were also synthesized by the reaction of arylidine malononitrile (4) with 6‐aminothiouracil (1). Moreover, the chemical behaviour of the produced pyrimidines towards different reagents was studied.
An Efficient Synthesis of Pyrazolo[3,4‐b]Pyridine Derivatives in Aqueous Media
Authors: Shi Da‐Qing , Shi Jing‐Wen , Yao Hao , Jiang Hong , Wang Xiang‐Shan 
Published: May 2015

AbstractA series of pyrazolo[3,4‐b]pyridines was synthesized by the reaction of 5‐aminopyrazole with benzylidenemalononitrile in aqueous media. The structures were characterized by IR, 1H NMR, and elemental analysis and were further confirmed by X‐ray diffraction analysis.
The Synthesis of 1,4‐Bis[N‐(4/6‐Substituted Benzothiazole‐2‐yl)‐N′‐Glycosylguanidino]Benzenes
Authors: Tian Tian , Cao Ling‐Hua 
Published: May 2015

AbstractThe starting material O‐protected glycosyl isothiocyanate (1˜3) was refluxed with 1,4‐diaminobenzene in CHCl3 under nitrogen atmosphere to give 1,4‐bis(N‐glycosyl)thioureidobenzene (4˜6). Then 1,4‐bis[N‐(4/6‐substituted benzothiazole‐2‐yl)‐N′‐glycosylguanidino]benzenes (8a˜8e, 9a˜9e, 10a˜10e) were obtained in good yield by reaction of compounds (4˜6) with 2‐amino‐4/6‐benzothizoles (7a˜7e) and HgCl2 in the presence of TEA in DMF. The structures of all 18 new compounds were confirmed by IR, 1H NMR, LC‐MS and elemental analysis. The bioactivity of anti‐HIV‐1 protease (HIV‐1 PR) and against angiotensin converting enzyme (ACE) have been evaluated.
Self‐Assembly, Spectroscopic and Electrochemical Studies of Nickel(II)‐4,8‐Diazaundecanediamide Complex
Authors: Chao Min‐Shiun , Lu Horng‐Hwa , Tsai Ming‐Liao , Ho Mei‐Chan 
Published: May 2015

AbstractThe self‐assembly of NiCl2·6H2O with a diaminodiamide ligand 4,8‐diazaundecanediamide (L‐2,3,2) gave a [Ni(C9H20N4O2)(Cl)(H2O)] Cl·2H2O (1). The structure of 1 was characterized by single‐crystal X‐ray diffraction analysis. Structural data for 1 indicate that the Ni(II) is coordinated to two tertiary N atoms, two O atoms, one water and one chloride in a distorted octahedral geometry. Crystal data for 1: orthorhombic, space group P 21nb, a = 9.5796(3) Å, b = 12.3463(4) Å, c = 14.6305(5) Å, Z = 4. Through NH···Cl–Ni (H···Cl 2.42 Å, N···Cl 3.24 Å, NH···Cl 158°) and OH···Cl–Ni contacts (H···Cl 2.36 Å, O···Cl 3.08 Å, OH···Cl 143°), each cationic moiety [Ni(C9H20N4O2) (Cl)(H2O)]+ in 1 is linked to neighboring ones, producing a charged hydrogen‐bonded 1D chainlike structure. Thermogrametric analysis of compound 1 is consistent with the crystallographic observations. The electronic absorption spectrum of Ni(L‐2,3,2)2+ in aqueous solution shows four absorption bands, which are assigned to the 3A2g → 3T2g, 3T2g → 1Eg, 3T2g → 3T1g, and 3A2g → 3T1g transitions of triplet‐ground state, distorted octahedral nickel(II) complex. The cyclic volammetric measurement shows that Ni2+ is more easily reduced than Ni(L‐2,3,2)2+ in aqueous solution.
Preparation, Characterization and Catalytic Performance of Carbon Nanotubes Promoted Ni‐B Amorphous Alloy
Authors: Hu Chang‐Yuan , Liao Xiao‐Ning , Li Feng‐Yi , Zhang Rong‐Bin , Zhang Rong‐Fa , Liu Ting‐Zhi 
Published: May 2015

AbstractNi‐B and Ni‐B/CNTs amorphous alloy catalysts were prepared by chemical reduction and impregnation‐chemical reduction methods, respectively, and characterized by TEM, ICP, XPS, XRD, BET and CO chemisorption techniques. Their catalytic activities were evaluated in acetylene selective hydrogenation reaction. Based on characterizations, the effects of carbon nanotubes on Ni‐B amorphous alloy were attributed to both its structure effect, dispersing Ni‐B particles, leading to bigger surface area of active nickel and enhancing the thermal stability, and the electronic effect, resulting in electron‐rich nickel centers. Therefore, the superior thermal stability and acetylene selective hydrogenation activities of Ni‐B/CNTs to Ni‐B amorphous catalyst were obtained in the present study.
PVC‐Based on Thiopyrilium Derivatives Membrane Electrodes for Determination of Histamine
Authors: Javanbakht Mehran , Mohammadi Ali , Ganjali Mohammad Reza , Norouzi Parviz , Faridbod Farnoush , Pirelahi Hooshang 
Published: May 2015

AbstractThis study describes novel histamine‐selective electrodes, having their basis on thiopyrilium (TP) derivatives as suitable ionophores. The electrodes were prepared by incorporating the TP derivatives into plasticized poly(vinyl chloride) (PVC) membranes. These electrodes demonstrate high selectivity as far as the histamine response is considered, as compared with many common inorganic anions and other kinds of amino acids. The influence of membrane composition, pH and the effect of lipophilic cationic and anionic additives on the response characteristics of the electrode were investigated. The resulting sensor based on 2,6‐bis(4‐dimethyl amino phenyl)‐4‐phenyl thiopyrilium perchlorate (TP4) responds to histamine in a wide concentration range from 5.0 × 10−6 to 1.0 × 10−1 M with a slope of 54.8 ± 0.6 mV decade−1 and detection limit of 3.0 μ mol L−1 (∼0.3 ppm). The electrode illustrates fast response time and good long‐term stability (more than 2 months). The ability to design histamine‐selective electrodes based on new thiopyrilium derivatives and both to alter selectivity and improve the response characteristics through structural changes to the charged ionophore, has been investigated. The prepared electrode was used for the determination of histamine in a synthetic human serum sample. Consequently, satisfactory recovery results were obtained over a wide concentration range of histamine.
Flow‐Injection Chemiluminometric Analysis of Thyroxine Hormone in a KMnO,4‐Na2SO3 System
Authors: Waseem Amir , Yaqoob Mohammad , Nabi Abdul 
Published: May 2015

AbstractAn analytical method consisting of flow injection sampling and chemiluminescence detection for the determination of thyroxine hormone is described. It is based on the weak chemiluminescent reaction of KMnO4 ‐ Na2SO3 in acidic medium, which is enhanced by the addition of thyroxine hormone. The chemiluminescence intensity was correlated linearly with concentration of thyroxine in the range of 1.0 × 10−7 – 2.0 × 10−6 mol L−1 (r2 = 0.9976) with a relative standard deviation (n = 4) in the range of 1.0 – 1.9%. The limit of detection (3σ blank) is 5.0 × 10−9 mol L−1 with a sample throughput of 180 h−1. The method has been applied to the determination of thyroxine in pharmaceutical preparations and the results are in good agreement with the value reported. Metal and non‐metal ions and some organic compounds commonly present in tablets and some amino acids were also studied for thyroxine determination.
Reaction of 1,6‐Dioxo‐2,4‐Diene with Aziridine and Secondary Amine
Authors: Sun Tsung‐Hsien , Ong Chi‐Wi 
Published: May 2015

AbstractThe (2E,4E)‐ and (2E,4Z)‐1‐phenyl‐1,6‐dioxo‐hepta‐2,4‐diene reacts with aziridine to give aziridinecyclopentenol 3. This product arises from an intermolecular Michael addition of a nitrogen lone pair to the less reactive enone, followed by an intramolecular aldol reaction of the enol with ketone. Furthermore, the initially formed enol did not undergo nucleophilic attack onto the aziridine ring to form heterocycles. Interestingly, the reaction with secondary amine did not give the cyclopentenol adduct, and this only leads to the isomerization of (2E,4Z)‐1‐phenyl‐1,6‐dioxo‐hepta‐2,4‐diene to the more stable (2E,4E)‐1‐phenyl‐1,6‐dioxo‐hepta‐2,4‐diene by addition to the more reactive enone.
Activation Mechanisms for Pseudomonas Species Lipase by Cardiovascular Drugs in Vitro
Authors: Lin Ming‐Cheng , Lai Gin‐Win , Lin Chung‐Sheng , Lin Gialih 
Published: May 2015

AbstractThe goal of this work was to determine the reaction mechanism for Pseudomonas species lipase activation by cardiovascular drugs such as lovastatin, simvastatin, amlodipine besylate, nifedipine, and hydralazine hydrochloride based on the results from enzyme kinetics. These drugs are the essential activators of Pseudomonas species lipase in the presence of triton‐X 100 or taurochloate in vitro. Moreover, QSAR studies show that the pKA values are correlated with the molecular weights of these drugs.
Spectrophotometric Studies on Some Arylazo Barbituric Acids and Arylazo Pyrimidine in Organic Solvents and in Buffer Solutions
Authors: Amrallah A. H. , Abdalla N. A. , El‐Haty E. Y. 
Published: May 2015

AbstractThe UV and visible spectra of some arylazo barbituric acids and arylazo pyrimidine in pure and mixed organic solvents of varying polarities have been studied. The different absorption bands displayed in the electronic spectra of these compounds are assigned and the possibility of the existence of these compounds in tautomeric equilibrium as well as in intra‐ and intermolecular H‐bonding were examined. The solute‐solvents molecular complexes liable to exist in polar‐nonpolar mixed solvents are investigated. The structure of the azo compounds were confirmed by 1H NMR and IR spectroscopy. The ionization processes of the compounds were investigated and the possible ionization constants were determined and discussed in terms of molecular structure of the azo compounds.
High Fluorine Content Bis(fluoro‐Ponytailed) Bipyridine Palladium Complexes as Catalyst for Mizoroki‐Heck Reactions under Fluorous Biphasic Catalysis Conditions
Authors: Lu Norman , Chen Shih‐Chieh , Lin Yan‐Chou , Cheng Yao‐Yi , Liu Ling‐Kang 
Published: May 2015

AbstractTwo highly fluorinated bipyridine derivatives, (4,4′‐bis(RfCH2OCH2)‐2,2′‐bpy) {Rf = n‐C10F21 (1a), n‐C10F23 (1b)}, have been synthesized starting from 4,4′‐bis(BrCH2)‐2,2′‐bpy and the corresponding fluorinated alkoxides. The fluorine contents of ligands 1a‐b are 62.3% and 63.3%, respectively, both being white solids, virtually insoluble in CH2Cl2 or DMF and highly fluorophilic with a partition ratio between DMF and n‐C8F18 less than 1:1000. The reaction of ligands 1a‐b with [Pd(CH3CN)2Cl2] results in novel Pd complexes [PdCl2(4,4′‐bis‐(RfCH2OCH2)‐2,2′‐bpy)] where Rf = n‐C10F21 (2a), n‐C10F23 (2b), respectively. The Pd complexes 2a‐b are pale yellow solids, soluble only in fluorinated solvents. The Pd complexes 2a‐b have been satisfactorily tested for Mizoroki‐Heck arylation under fluorous biphasic catalysis conditions in that the Pd complexes 2a‐b are easily recovered and maintain good catalytic activity after 8 consecutive cycles (> 90% yield). The TGA studies indicate that the Pd complexes 2a‐b are thermally stable up to 300 °C.