bluuebunny/crossref_metadata_2025_split huggingface dataset:
Crosstalk suppression bandwidth optimisation of a vertically coupled ring resonator add/drop filter
Authors: Mansoor Riyadh , Koziel Slawomir , Sasse Hugh , Duffy Alistair 
Published: February 2015

In this study, a vertical coupled single ring resonator add/drop filter is simulated and the effect of different design parameters on the crosstalk suppression bandwidth is numerically investigated. Crosstalk suppression is defined as the difference between drop port and through port spectral responses. In a vertically coupled ring resonator, coupling efficiency between the evanescent tails of modes on the bus and bent waveguides is controlled by vertical separation and lateral deviation between waveguides. Designing a small size (single ring) add/drop filter that provides an increased crosstalk suppression bandwidth (to drop 10 Gbps non‐return to zero signals) is proposed. As the analytical calculations cannot produce an accurate prediction of the design parameters, a simulation‐driven design optimisation procedure is used to determine the values of the design parameters that produce a 21 GHz crosstalk suppression bandwidth.
Surfactant coated magnetic nanoparticle‐based solid‐phase extraction coupled with spectrophotometric detection for determination of ultra‐trace amounts of indomethacin in biological fluids
Authors: Amoli‐Diva Mitra , Pourghazi Kamyar , Pourasadollah‐Karani Hossein 
Published: February 2015

A novel mixed hemimicelle‐based solid‐phase extraction method using cetyltrimethylammonium bromide (CTAB) adsorbed onto the surface of magnetic Fe3O4 nanoparticles was developed for extraction/preconcentration of ultra‐trace amounts of indomethacin from biological fluids. Magnetic nanoparticles were synthesised via a simple chemical co‐precipitation method and characterised by a transmission electron microscope, an X‐ray diffractometer and Fourier transform infrared techniques. The method utilises the unique properties of Fe3O4 nanoparticles including high surface area and superparamagnetism causing rapid separation (<20 min) and low adsorbent usage (only 50 mg). A comprehensive study on the parameters affecting the adsorption efficiency such as the amount of CTAB, pH of the solution, desorption conditions, amount of Fe3O4 nanoparticles, extraction and preconcentration time, sample volume and ionic strength are presented. Under optimum conditions, the method's linearity was over a range of 25–450 ng ml−1. ‏ The limit of detection of 8.6 ng ml−1, an enrichment factor of 99 and the relative standard deviation (%RSD) of 1.9% (for a concentration of 50 ng ml−1) were obtained. The method was successfully applied to determine indomethacin in human plasma and urine samples. Good recoveries (89–102%) with low %RSD, (1.7–2.7%) were achieved.
CD47 regulates the phagocytic clearance and replication of thePlasmodium yoeliimalaria parasite
Authors: Banerjee Rajdeep , Khandelwal Sanjay , Kozakai Yukiko , Sahu Bikash , Kumar Sanjai 
Published: February 2015

SignificanceSeveralPlasmodiumspecies exhibit age-based preference for the red blood cells (RBC) they invade, with implications for virulence and disease severity. CD47, a marker of self, prevents the early clearance of cells by phagocytosis. We report here that in the absence of CD47, growth of aPlasmodiumspecies that preferentially infects CD47hiyoung RBC is highly attenuated, and the macrophages from CD47−/−mice are more effective in phagocytizing the malaria-parasitized RBC than wild-type mice. We suggest that preferential invasion of young RBC is an evolutionary adaptation that shields the malaria parasite from phagocytic clearance and controls parasitemia, as fewer RBC are available for invasion. Modulation of CD47 levels by antibody treatment may have therapeutic value in patients with severe malaria.
Tetramers reveal IL-17–secreting CD4+T cells that are specific for U1-70 in lupus and mixed connective tissue disease
Authors: Kattah Nicole H. , Newell Evan W. , Jarrell Justin Ansel , Chu Alvina D. , Xie Jianming , Kattah Michael G. , Goldberger Ofir , Ye Jessica , Chakravarty Eliza F. , Davis Mark M. , Utz Paul J. 
Published: February 2015

SignificancePatients with the autoimmune disease systemic lupus erythematosus (SLE) develop pathogenic antibodies against their own “self”-antigens. The development of such autoantibodies is thought in part to require help from CD4+T cells that also recognize the same self-antigens and direct autoantibody production. In this study, antigen-specific CD4+T cells in lupus are identified and tracked for the first time using tetramers containing peptides from the spliceosomal protein U1-70. The proportion of circulating, tetramer-positive CD4+cells correlates with the presence of U1-70–specific autoantibodies, and antigen-specific T cells are directly implicated in disease activity by their production of the proinflammatory cytokine IL-17. The role of these cells in disease pathology makes them candidate targets for therapeutic intervention.
Learning to Manage and Managing to Learn: Sustaining Freshwater Recreational Fisheries in a Changing Environment
Authors: Hansen Gretchen J. A. , Gaeta Jereme W. , Hansen Jonathan F. , Carpenter Stephen R. 
Published: February 2015

Abstract
Freshwaters are being transformed by multiple environmental drivers, creating uncertainty about future conditions. One way of coping with uncertainty is to manage for resilience to unanticipated events while facilitating learning through adaptive management. We outline the application of these strategies to freshwater recreational fisheries management using a case study in Wisconsin, USA, where black bass (Micropterus spp.) populations are increasing, while Walleye (Sander vitreus) populations are decreasing. Managing for heterogeneity in functional groups (e.g., age classes and prey species of sport fishes), fishery objectives, and regulations can increase resilience, although heterogeneity must be balanced with replication to facilitate learning. Monitoring designed to evaluate management objectives and inform about critical uncertainties, when combined with heterogeneity, creates opportunities for adaptive management, another critical resilience strategy. Although barriers exist to implementing resilience strategies, management designed to accommodate uncertainty and illuminate its consequences is needed to maintain critical fisheries in a rapidly changing world.
Los cuerpos de agua dulce están siendo transformados por múltiples factores ambientales, lo que genera incertidumbre sobre lo que sucederá en el futuro. Una forma de enfrentar esta incertidumbre es el manejo de la resiliencia con respeto a eventos no anticipados y, simultáneamente, facilitar el aprendizaje a través del manejo adaptativo. En este trabajo se muestra la aplicación de estas estrategias en el manejo de pesquerías recreativas de agua dulce tomando un caso de estudio en Wisconsin, en el que las poblaciones de la lobina negra (Micropterus spp.) están incrementándose, en tanto que las de la lucioperca americana (Sander vitreus) están disminuyendo. El manejo enfocado en la heterogeneidad de grupos funcionales (p.e., ciertas clases de edad y presas de peces de pesca deportiva), en los objetivos y en las regulaciones de la pesquería pueden aumentar la resiliencia, no obstante atender la heterogeneidad debe equilibrarse usando réplicas que faciliten el aprendizaje. El monitoreo diseñado para evaluar los objetivos del manejo e informar acerca de imprecisiones importantes que, al combinarse con la heterogeneidad, generan oportunidades para el manejo adaptativo, representa otra estrategia crítica para incrementar la resiliencia. Aunque existen obstáculos para implementar las estrategias enfocadas en la resiliencia, se necesita un manejo que incorpore la incertidumbre y que advierta sobre sus consecuencias, con el fin de mantener vivas importantes pesquerías en un mundo que está en constante cambio.
A restriction estimate using polynomial partitioning
Authors: Guth Larry 
Published: February 2015

If

S
S

is a smooth compact surface in

R

3

\mathbb {R}^3

with strictly positive second fundamental form, and

E
S

E_S

is the corresponding extension operator, then we prove that for all

p
>
3.25

p > 3.25

,

‖

E
S

f

‖

L
p

(

R

3

)

≤
C
(
p
,
S
)
‖
f

‖

L
∞

(
S
)

\| E_S f\|_{L^p(\mathbb {R}^3)} \le C(p,S) \| f \|_{L^\infty (S)}

. The proof uses polynomial partitioning arguments from incidence geometry.
Surface modification of carbon steel reinforcement of concrete
Authors: Rendón Belmonte Mariela , Madrid Miguel Martínez , Pérez-Quiroz José Trinidad , Salas Benjamín Valdez , Juarez-Arellano Erick A. , Schorr Miguel 
Published: February 2015

Purpose
– The purpose of this paper was to characterize the surface of steel reinforcement of concrete under cathodic protection (CP), submerged in seawater, to understand the surface changes due to the application of CP and their consequences on cathodic current requirements.

Design/methodology/approach
– Reinforced concrete specimens with applied CP were immersed in natural seawater. The experimental methodology included monitoring of corrosion potential (Ecorr); measurement of galvanic current (Igalv), protection potential (Eprotection) and the depolarization potential of steel during the time of exposure; and electrochemical impedance spectroscopy (EIS). The chemical composition of the steel surface was assessed using X-ray diffraction (XRD).

Findings
– The application of CP leads to the formation of a deposit on the steel surface that according to XRD results, Pourbaix diagram and physical characteristics, is a protective oxide: magnetite (Fe3O4). This oxide causes a decrease in the corrosion rate and requires application of the protection current. It was found that the surface remained protected even after eight days when the CP system was interrupted.

Research limitations/implications
– It is necessary to carry out analysis of the chemical composition of deposits formed on the steel surface, perhaps using X-ray photoelectron spectroscopy, Mössbauer, to verify the presence of the magnetite.

Practical implications
– Determination of the main cause of the decrease in current required for protection and deposit formation conditions will enable the design of a CP system to be optimized and economized. At present, the CP design considers only a constant current value for the duration of the protection time.

Originality/value
– CP is a technique that has proven effective for the protection of metal structures. However, little attention has been devoted to the surface changes that occur under applied CP and their impact on the electrochemical behavior of the system. This paper describes the phenomena produced at the metal surface and determines kinetic parameters and their consequences on the CP behavior.
Parametric virtual lower body of elderly women for apparel industry
Authors: Park Sunmi , Nam Yunja , Choi Kuengmi 
Published: February 2015

Purpose– The purpose of this paper is to develop a virtual body that resembles the customer’s body shape using only the minimum information provided by the customer and without requiring individually scanned data.Design/methodology/approach– The target of this study includes the three-dimensional scanned data of 91 senior women aged 60 or older and human body measurement data of 268 people. The parametric virtual body was generated in three steps: a basic virtual body, a trans-shaped virtual body, and a trans-sized virtual body.Findings– Using organic relationships found in the body shape factors of the lower body, this study developed an algorithm to generate elderly women’s parametric virtual lower body that is quick and reproducible. Having tested the reproducibility of the algorithm, the parametric virtual body showed excellent reproducibilityvis-à-visthe personal scanned data in both the shape acceptability and size acceptability.Originality/value– Because virtual bodies in this study are based on the results of body shape analysis related to apparel design, those resembling customer body shapes can be quickly and accurately generated. In addition, because body shape information for target groups is provided to the clothing manufacturers, it will likely contribute significantly to enhancing clothes fitting.
ARIMA modelling of Lithuanian house price index
Authors: Jadevicius Arvydas , Huston Simon 
Published: February 2015

Purpose– This paper aims to investigate Lithuanian house price changes. Its twin motivations are the importance of information on future house price movements to sector stakeholders and the limited number of related Lithuanian property market studies.Design/methodology/approach– The study employs ARIMA modelling approach. It assesses whether past is a good predictor of the future. It then examines issues relating to an application of this univariate time-series modelling technique in a forecasting context.Findings– As the results of the study suggest, ARIMA is a useful technique to assess broad market price changes. Government and central bank can use ARIMA modelling approach to forecast national house price inflation. Developers can employ this methodology to drive successful house-building programme. Investor can incorporate forecasts from ARIMA models into investment strategy for timing purposes.Research limitations/implications– Certainly, there are number of limitations attached to this particular modelling approach. Firm predictions about house price movements are also a challenge, as well as more research needs to be done in establishing a dynamic interrelationship between macro variables and the Lithuanian housing market.Originality/value– Although the research focused on Lithuania, the findings extend to global housing market. ARIMA house price modelling provides insights for a spectrum of stakeholders. The use of this modelling approach can be employed to improve monetary policy oversight, facilitate planning for infrastructure or social housing as a countercyclical policy and mitigate risk for investors. What is more, a greater appreciation of Lithuania housing market can act as a bellwether for real estate markets in other trade-exposed small country economies.
Survival of Lactobacillus casei strain Shirota in the intestines of healthy Chinese adults
Authors: Wang Ran , Chen Shanbin , Jin Junhua , Ren Fazheng , Li Yang , Qiao Zhenxing , Wang Yue , Zhao Liang 
Published: February 2015

ABSTRACTLactobacillus casei strain Shirota (LcS) is a widely used probiotic strain with health benefits. In this study, the survival of LcS in the intestines of healthy Chinese adults was assessed and the effects of LcS on stool consistency, stool SCFAs and intestinal microbiota evaluated. Subjects consumed 100 mL per day of a probiotic beverage containing 1.0 × 108 CFU/mL of LcS for 14 days. LcS were enumerated using a culture method and the colony identity confirmed by ELISA. Fourteen days after ingestion, the amount of LcS recovered from fecal samples was between 6.86 ± 0.80 and 7.17 ± 0.57 Log10 CFU/g of feces (mean ± SD). The intestinal microbiotas were analyzed by denaturing gradient gel electrophoresis. Principal component analysis showed that consuming LcS significantly changed fecal microbiota profiles. According to redundancy analysis, the amounts of 25 bacterial strains were significantly correlated with LcS intake (P < 0.05), 11 of them positively and fourteen negatively. Concentrations of acetic acid and propionic acid in feces were significantly lower during the ingestion period than during the baseline period (P < 0.05). These results confirm that LcS can survive passage through the gastrointestinal tract of Chinese people; however, they were found to have little ability to persist once their consumption had ceased. Furthermore, consumption of probiotic beverages containing LcS can modulate the composition of the intestinal microbiota on a long‐term basis, resulting in decreased concentrations of SCFAs in the gut.
Fatty acid‐releasing activities in Sinorhizobium meliloti include unusual diacylglycerol lipase
Authors: Sahonero‐Canavesi Diana X. , Sohlenkamp Christian , Sandoval‐Calderón Mario , Lamsa Anne , Pogliano Kit , López‐Lara Isabel M. , Geiger Otto 
Published: February 2015

SummaryPhospholipids are well known for their membrane‐forming properties and thereby delimit any cell from the exterior world. In addition, membrane phospholipids can act as precursors for signals and other biomolecules during their turnover. Little is known about phospholipid signalling, turnover and remodelling in bacteria. Recently, we showed that a FadD‐deficient mutant of Sinorhizobium meliloti, unable to convert free fatty acids to their coenzyme A derivatives, accumulates free fatty acids during the stationary phase of growth. Enzymatic activities responsible for the generation of these free fatty acids were unknown in rhizobia. Searching the genome of S. meliloti, we identified a potential lysophospholipase (SMc04041) and two predicted patatin‐like phospholipases A (SMc00930, SMc01003). Although SMc00930 as well as SMc01003 contribute to the release of free fatty acids in S. meliloti, neither one can use phospholipids as substrates. Here we show that SMc01003 converts diacylglycerol to monoacylglycerol and a fatty acid, and that monoacylglycerol can be further degraded by SMc01003 to another fatty acid and glycerol. A SMc01003‐deficient mutant of S. meliloti transiently accumulates diacylglycerol, suggesting that SMc01003 also acts as diacylglycerol lipase (DglA) in its native background. Expression of the DglA lipase in Escherichia coli causes lysis of cells in stationary phase of growth.
Perinatal outcome after first‐trimester risk assessment in monochorionic and dichorionic twin pregnancies: a population‐based register study
Authors: Kristiansen MK , Joensen BS , Ekelund CK , Petersen OB , Sandager P ,   with the Danish Fetal Medicine Study Group
Published: February 2015

ObjectiveTo evaluate the influence of chorionicity on outcome in twin pregnancies with two live fetuses at the nuchal translucency scan in the first trimester.DesignPopulation‐based register study.SettingDenmark.PopulationA cohort of 3621 twin pregnancies, 84.3% dichorionic (DC) pregnancies and 15.7% monochorionic (MC) pregnancies (15% diamniotic [MCDA] and 0.7% monoamniotic [MCMA]).MethodsA cohort study based on data collected from the Danish Fetal Medicine Database from July 2008 to July 2011.Main outcome measuresFetal loss rate before week 22, intrauterine death rate from week 22 to birth, and neonatal mortality.ResultsSignificantly more DC than MC pregnancies resulted in at least one live born infant—98.2% versus 92.3% in MCDA (P < 0.05) and 66.7% in MCMA pregnancies (P < 0.05). The rates of spontaneous loss of both fetuses before week 22 were 0.9, 2.4, and 20.8% for DC, MCDA and MCMA twins, respectively (P < 0.05). The rate of intrauterine death of one fetus after week 22 was higher in MCDA twins than DC twins 1.7% versus 0.6% (P < 0.05). We found no significant difference in the rate of neonatal death.ConclusionsThe risk of spontaneous loss of both fetuses before week 22 of gestation was significantly higher in MCMA and MCDA pregnancies than in DC pregnancies, and significantly higher in MCMA pregnancies than in MCDA pregnancies. After week 22 the risk of loss of one fetus after week 22 was significantly higher in MCDA pregnancies than in DC pregnancies.
Wide field of view CT and acromioclavicular joint instability: A technical innovation
Authors: Dyer David R , Troupis John M , Kamali Moaveni Afshin 
Published: February 2015

SummaryA 21‐year‐old female with a traumatic shoulder injury is investigated and managed for symptoms relating to this injury. Pathology at the acromioclavicular joint is detected clinically; however, clinical examination and multiple imaging modalities do not reach a unified diagnosis on the grading of this acromioclavicular joint injury. When management appropriate to that suggested injury grading fail to help the patient's symptoms, further investigation methods were utilised. Wide field of view, dynamic CT (4D CT) is conducted on the patient's affected shoulder using a 320 × 0.5 mm detector multislice CT. Scans were conducted with a static table as the patient completed three movements of the affected shoulder. Capturing multiple data sets per second over a z‐axis of 16 cm, measurements of the acromioclavicular joint were made, to show dynamic changes at the joint. Acromioclavicular (AC) joint translations were witnessed in three planes (a previously unrecognised pathology in the grading of acromioclavicular joint injuries). Translation in multiple planes was also not evident on careful clinical examination of this patient. AC joint width, anterior‐posterior translation, superior‐inferior translation and coracoclavicular width were measured with planar reconstructions while volume‐rendered images and dynamic sequences aiding visual understanding of the pathology. Wide field of view dynamic CT (4D CT) is an accurate and quick modality to diagnose complex acromioclavicular joint injury. It provides dynamic information that no other modality can; 4D CT shows future benefits for clinical approach to diagnosis and management of acromioclavicular joint injury, and other musculoskeletal pathologies.
Linkage mapping with paralogs exposes regions of residual tetrasomic inheritance in chum salmon (Oncorhynchus keta)
Authors: Waples R. K. , Seeb L. W. , Seeb J. E. 
Published: February 2015

AbstractGene sequence similarity due to shared ancestry after a duplication event, that is paralogy, complicates the assessment of genetic variation, as sequences originating from paralogs can be difficult to distinguish. These confounded sequences are often removed prior to further analyses, leaving the underlying loci uncharacterized. Salmonids have only partially rediploidized subsequent to a whole‐genome duplication; residual tetrasomic inheritance has been observed in males. We present a maximum‐likelihood‐based method to resolve confounded paralogous loci by observing the segregation of alleles in gynogenetic haploid offspring and demonstrate its effectiveness by constructing two linkage maps for chum salmon (Oncorhynchus keta), with and without these newly resolved loci. We find that the resolved paralogous loci are not randomly distributed across the genome. A majority are clustered in expanded subtelomeric regions of 14 linkage groups, suggesting a significant fraction of the chum salmon genome may be missed by the exclusion of paralogous loci. Transposable elements have been proposed as drivers of genome evolution and, in salmonids, may have an important role in the rediploidization process by driving differentiation between homeologous chromosomes. Consistent with that hypothesis, we find a reduced fraction of transposable element annotations among paralogous loci, and these loci predominately occur in the genomic regions that lag in the rediploidization process.