bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Copper‐Catalyzed Dehydrogenative Reaction: Synthesis of Amide from Aldehydes and Aminopyridine.
Authors: Yang Sizhuo , Yan Hao , Ren Xiaoyu , Shi Xiaokang , Li Jian , Wang Yuling , Huang Guosheng 
Published: November 2013

AbstractA simple protocol using air as the oxidant is developed for the synthesis of benzamides via oxidative amidation of benzaldehydes with aminopyridine derivatives.
ChemInform Abstract: Synthesis of S‐Aryl Arenethiosulfonates from N,N‐Di(arenesulfonyl)hydrazines: Reduction of Sulfonyl Chlorides with an Organic Reagent.
Authors: Iwata Satoshi , Senoo Masato , Hata Takeshi , Urabe Hirokazu 
Published: November 2013

AbstractThe presented reaction is limited to N,N‐Di(arenesulfonyl)hydrazines and does not work with N,N‐Di(alkylsulfonyl)hydrazines.
ChemInform Abstract: Organocatalytic Asymmetric Sulfa‐Michael Addition of Thiols to α,β‐Unsaturated Hexafluoroisopropyl Esters: Expeditious Access to (R)‐Thiazesim.
Authors: Fang Xin , Li Jun , Wang Chun‐Jiang 
Published: November 2013

AbstractApplication of this method is demonstrated by the total synthesis of (R)‐Thiazesim (VI) that is obtained in 75% yield and 98% e.e.
ChemInform Abstract: Aerobic Oxysulfonylation of Alkenes Leading to Secondary and Tertiary β‐Hydroxysulfones.
Authors: Lu Qingquan , Zhang Jian , Wei Fuliang , Qi Yue , Wang Huamin , Liu Zhiliang , Lei Aiwen 
Published: November 2013

AbstractThe novel title reaction tolerates a wide range of functional groups and proceeds without any additional initiators.
ChemInform Abstract: Synthesis of Substituted Biaryls via Suzuki, Stille and Hiyama Cross‐Coupling and Homo‐Coupling Reactions by CN‐Dimeric and Monomeric ortho‐Palladated Catalysts.
Authors: Hajipour Abdol R. , Rafiee Fatemeh 
Published: November 2013

AbstractThe monomeric ortho‐palladated catalyst (DMPA) is successfully applied to the title coupling reactions [43 examples].
ChemInform Abstract: One‐Pot Synthesis of Novel Spiro[quinazoline/pyrimidine]ones via Multi Component Reaction.
Authors: Meshram Gangadhar , Wagh Pramod , Deshpande Shruti , Amratlal Vipul 
Published: November 2013

AbstractA new and facile one‐pot method for synthesis of the title scaffolds is presented and further extended by employing two other reactive ketones instead of isatin.
ChemInform Abstract: Synthesis of cis‐C‐Iodo‐N‐tosyl‐aziridines Using Diiodomethyllithium: Reaction Optimization, Product Scope and Stability, and a Protocol for Selection of Stationary Phase for Chromatography.
Authors: Boultwood Tom , Affron Dominic P. , Trowbridge Aaron D. , Bull James A. 
Published: November 2013

AbstractThe excellent cis‐diastereoselective title synthesis provides a wide range of cis‐iodoaziridines including the first examples of alkyl‐substituted iodoaziridines (≥95 % ds.).
ChemInform Abstract: A Thioannulation Approach to Substituted Thiophenes from Morita—Baylis—Hillman Acetates of Acetylenic Aldehydes.
Authors: Reddy Chada Raji , Valleti Redi Rani , Reddy Motatipally Damoder 
Published: November 2013

AbstractThe new and versatile protocol for the title approach proceeds under mild and metal‐free reaction conditions and through a tandem allylic substitution/deacetylative thiocycloisomerization.
ChemInform Abstract: Highly Regioselective and Metal‐Free γ‐Addition of β‐Keto Esters to Isatins, Catalyzed by DABCO: Direct Access to Novel Class of Diversely Functionalized 3‐Hydroxy‐2‐oxindole Scaffolds.
Authors: Thakur Pramod Bhagwan , Sirisha Katukuri , Sarma Akella Venkata Subrahmanya , Nanubolu Jagadeesh Babu , Meshram Harshadas Mitaram 
Published: November 2013

AbstractThe DABCO catalyzed aldol reaction of isatins with β‐keto esters provides unexpected γ‐addition products with high regioselectivity.
ChemInform Abstract: Cyclization‐Carbonylation‐Cyclization Coupling Reaction of α, β‐Alkynic Hydrazones with Palladium(II)‐Bisoxazoline Catalyst.
Authors: Kusakabe Taichi , Sagae Hiroshi , Kato Keisuke 
Published: November 2013

AbstractThe title reaction affords symmetrical ketones (III) bearing two pyrazole groups and is general for a wide range of substrates.
ChemInform Abstract: Sequential [3 + 2] Cycloaddition/Air Oxidation Reactions: Triazoloyl Ion Assisted Oxidative Cleavage of Alkynes.
Authors: Ponpandian Thanasekaran , Muthusubramanian Shanmugam , Rajagopal Sridharan 
Published: November 2013

AbstractBenzaldehyde or formaldehyde, respectively, are the byproducts in these reactions.
ChemInform Abstract: A Facile Synthesis of 4,6,7,8,8a,9‐Hexahydropyrrolo[1,2‐a][1,2,3]triazolo[1,5‐d]pyrazines by a Three‐Component Coupling Reaction Followed by Intramolecular 1,3‐Dipolar Cycloaddition.
Authors: Dhondge Attrimuni P. , Afraj Shakil N. , Nuzlia Cut , Chen Chinpiao , Lee Gene‐Hsian 
Published: November 2013

AbstractCompounds (IV) and (VII) are generally isolated in < 89% d.e.
ChemInform Abstract: The Syntheses, Molecular Structures, Spectroscopic Properties (IR, Micro‐Raman, NMR and UV—vis) and DFT Calculations of Antioxidant 3‐Alkyl‐4‐ [3‐methoxy‐4‐(4‐methylbenzoxy)benzylidenamino] ‐4,5‐dihydro‐1H‐1,2,4‐triazol‐5‐one Molecules.
Authors: Goekce Halil , Bahceli Semiha , Akyildirim Onur , Yuesek Haydar , Kol Oezlem Guersoy 
Published: November 2013

AbstractThe title new compounds are screened for their in vitro antioxidant activity and demonstrated a marked capacity for iron binding.
ChemInform Abstract: Synthesis of Substituted 3‐Iodocoumarins and 3‐Iodobutenolides via Electrophilic Iodocyclization of Ethoxyalkyne Diols.
Authors: Reddy Maddi Sridhar , Thirupathi Nuligonda , Babu Madala Hari , Puri Surendra 
Published: November 2013

AbstractThe new method to synthesize various iodocoumarins and iodobutenolides proceeds via an exclusive 6‐endo‐dig iodocyclization of 3‐ethoxy‐1‐(2‐alkoxyphenyl)‐2‐yn‐1‐ols and 5‐endo‐dig iodocyclization of 1‐alkoxy‐4‐ethoxy‐3‐yn‐1,2‐diols, respectively.
ChemInform Abstract: Organocatalyzed Michael—Michael Cascade Reaction: Asymmetric Synthesis of Polysubstituted Chromans.
Authors: Jia Zhen‐Xin , Luo Yong‐Chun , Cheng Xi‐Na , Xu Peng‐Fei , Gu Yu‐Cheng 
Published: November 2013

AbstractThe title reaction provides a mild and efficient approach for the synthesis of the chiral benzopyrans (III) and (VI) with three consecutive stereocenters.
ChemInform Abstract: Palladium(II)‐Catalyzed Dehydrogenative Cross‐Coupling Between Two Csp3—Bonds: Unexpected C=C Bond Formation.
Authors: Li Gaocan , Qian Shengyou , Wang Chunxia , You Jingsong 
Published: November 2013

AbstractThis is the first method for the construction of C=C double bonds via palladium‐catalyzed oxidative cross‐coupling between two Csp3—H bonds without the need for an extra oxidant.
ChemInform Abstract: Rhodium(III)‐Catalyzed Oxidative Olefination of Pyridines and Quinolines: Multigram‐Scale Synthesis of Naphthyridinones.
Authors: Zhou Jun , Li Bo , Hu Fang , Shi Bing‐Feng 
Published: November 2013

AbstractSeveral further synthetic transformations of the primary reaction products are demonstrated, including strategies for the synthesis of some biologically active compounds.
ChemInform Abstract: A Highly Diastereo‐ and Enantioselective Synthesis of Tetrahydroquinolines: Quaternary Stereogenic Center Inversion and Functionalization.
Authors: Luo Chaosheng , Huang Yong 
Published: November 2013

AbstractA variety of tetrahydroquinolines is prepared with high dia‐ and enantioselectivities using one or two different anilines.
ChemInform Abstract: Heteroatom‐Guided, Palladium‐Catalyzed Regioselective C—H Functionalization in the Synthesis of 3‐Arylquinolines.
Authors: Tiwari Virendra Kumar , Pawar Govind Goroba , Das Riki , Adhikary Amit , Kapur Manmohan 
Published: November 2013

AbstractA new approach for the regioselective functionalization of the C‐3‐position of quinolines is described.
ChemInform Abstract: Photocycloadditions of Substituted Oxazoles with Isoquinoline‐1,3,4‐trione—Chemo‐, Regio‐, Diastereoselectivities and Transformation of the Photocycloadducts.
Authors: Huang Cheng‐mei , Jiang Heng , Wang Ru‐zhi , Quah Ching Kheng , Fun Hoong‐Kun , Zhang Yan 
Published: November 2013

AbstractDifferent from other α‐diketones, photocycloadditions of trione (I) with oxazoles (II) proceed exclusively via a [2 + 2] pathway with exclusive involvement of the C(4) carbonyl group.
ChemInform Abstract: Cascade Electrophilic Iodocyclization: Efficient Preparation of 4‐Iodomethyl Substituted Tetrahydro‐β‐carbolines and Formal Synthesis of Oxopropaline G.
Authors: Song Hongjian , Liu Yongxian , Wang Qingmin 
Published: November 2013

Abstract4‐Iodomethyl substituted tetrahydro‐β‐carbolines, the core structure of numerous natural products and bioactive molecules, are readily prepared via I2‐promoted cascade electrophilic cyclization.
ChemInform Abstract: Tetrahydroquinolines and Benzazepines Through Catalytic Diastereoselective Formal [4 + 2]‐Cycloaddition Reactions Between Donor—Acceptor Cyclopropenes and Imines.
Authors: Truong Phong M. , Mandler Michael D. , Zavalij Peter Y. , Doyle Michael P. 
Published: November 2013

AbstractRegio‐ and diastereoselective Lewis acid catalyzed cycloaddition reactions between imines and donor—acceptor cyclopropenes generated from silyl‐protected enoldiazoacetates (I) provide direct access to stable cyclopropane‐fused tetrahydroquinolines and, with cyclopropane ring opening under mild conditions, to 1H‐benzazepine derivatives (IX).
ChemInform Abstract: Protecting‐Group‐Free Total Synthesis of (—)‐Rhazinilam (VII) and (—)‐Rhazinicine (VIII) Using a Gold‐Catalyzed Cascade Cyclization.
Authors: Sugimoto Kenji , Toyohima Kazuki , Nonaka Shiori , Kotaki Kenta , Ueda Hirofumi , Tokuyama Hidetoshi 
Published: November 2013

AbstractFor the first time the asymmetric total synthesis of the title compound (VII) is presented.
ChemInform Abstract: Asymmetric Ruthenium‐Catalyzed Hydrogenation of 2‐ and 2,9‐Substituted 1,10‐Phenanthrolines.
Authors: Wang Tianli , Chen Fei , Qin Jie , He Yan‐Mei , Fan Qing‐Hua 
Published: November 2013

AbstractThe first highly enantio‐ and diastereoselective hydrogenation of 2,9‐ and 1,10‐phenanthrolines using a chiral cationic ruthenium diamine catalyst is presented.
ChemInform Abstract: Cascade Synthesis of Azoquinazolinones by Cu(I)‐Catalyzed C—N Coupling/C—H Activation/C—N Formation Reactions under O2.
Authors: Chen Dingben , Chen Qiufang , Liu Miaochang , Dai Shuangqun , Huang Ling , Yang Jianguo , Bao Weiliang 
Published: November 2013

AbstractA convenient one‐pot protocol is presented for the reaction of 2‐iodo‐benzamides with various N‐heterocycles to give azoquinazolinone derivatives via the title process.
ChemInform Abstract: Bifunctionalized Allenes. Part 9. An Efficient Method for Regioselective Synthesis of 4‐Heteroatom‐Functionalized Allenecarboxylates.
Authors: Ivanov Ivaylo K. , Parushev Ivaylo D. , Christov Valerij Ch. 
Published: November 2013

AbstractThis reaction proceeds via an atom economical [2,3]‐sigmatropic rearrangement of 2‐heteroatom‐functionalized alk‐3‐ynecarboxylates.
ChemInform Abstract: Hydroxyphosphinylation Reaction of 3‐Cyclopropylideneprop‐2‐en‐1‐ones via C—P σ‐Bond Cleavage.
Authors: Miao Maozhong , Cao Jian , Huang Xian , Wu Luling 
Published: November 2013

AbstractAn unexpected hydroxyphosphinylation of 3‐cyclopropylideneprop‐2‐en‐1‐ones with phosphines is reported providing a unique regio‐ and stereoselective synthesis of highly functionalized (Z)‐alkenyl cyclopropanols with important potential.
ChemInform Abstract: Rhodium(III)‐Catalyzed Oxidative Coupling Through C—H Bond Cleavage Directed by Phosphinoxy Groups.
Authors: Unoh Yuto , Hashimoto Yuto , Takeda Daisuke , Hirano Koji , Satoh Tetsuya , Miura Masahiro 
Published: November 2013

AbstractA straightforward synthesis of phosphaisocoumarins is achieved by the rhodium‐catalyzed oxidative coupling of diarylphosphinic and phenylphosphonic acid derivatives with alkynes.
ChemInform Abstract: Salimyxins and Enhygrolides: Antibiotic, Sponge‐Related Metabolites from the Obligate Marine Myxobacterium Enhygromyxa salina.
Authors: Felder Stephen , Kehraus Stefan , Neu Edith , Bierbaum Gabriele , Schaeberle Till F. , Koenig Gabriele M. 
Published: November 2013

AbstractSalimyxin A (I), salimyxin B (II), enhygrolide A (III), and enhygrolide B (IV) are isolated.
ChemInform Abstract: Stereocontrolled Total Synthesis of Tetrodotoxin from Myo‐inositol and D‐Glucose by Three Routes: Aspects for Constructing Complex Multi‐functionalized Cyclitols with Branched‐chain Structures
Authors: Sato Ken‐ichi , Akai Shoji , Yoshimura Juji 
Published: November 2013

AbstractReview: 107 refs.
ChemInform Abstract: Diels—Alder Reactions of 12‐Hydroxy‐9(10→20)‐5aH‐abeo‐abieta‐ 1(10),8(9),12(13)‐triene‐11,14‐dione
Authors: Majetich George , Zhang Yong , Tian Xinrong , Zou Ge , Li Yang , Wang Yangyang , Hu Shougang , Huddleston Eric 
Published: November 2013

AbstractReview: 102 refs.
ChemInform Abstract: Novel Investigation of 1,5‐Diamino‐4‐methyltetrazolium Perchlorate [C2H7N6]+ [ClO4]‐: A Prospective Challenge to Nitrogen‐rich Ionic Salts and Health Risk
Authors: Swain Pravat K. 
Published: November 2013

AbstractReview: synthesis, structural aspects, spectroscopic studies, and physico‐chemical properties of the title perchlorate; 43 refs.
ChemInform Abstract: Polyurethanes: Versatile Materials and Sustainable Problem Solvers for Today′s Challenges
Authors: Engels Hans‐Wilhelm , Pirkl Hans‐Georg , Albers Reinhard , Albach Rolf W. , Krause Jens , Hoffmann Andreas , Casselmann Holger , Dormish Jeff 
Published: November 2013

AbstractReview: 103 refs.
Chiral 3D Open‐Framework Material Ni(D‐cam)(H2O)2 Used as GC Stationary Phase
Authors: Xie Shengming , Wang Bangjin , Zhang Xinhuan , Zhang Junhui , Zhang Mei , Yuan Liming 
Published: November 2013

ABSTRACTMetal‐organic frameworks (MOFs) have been explored for analytical applications because of their outstanding properties such as high surface areas, flexibility and specific structure features, especially for chromatography application in recent years. In this work, a chiral MOF Ni(D‐cam)(H2O)2 with unusual integration of molecular chirality, absolute helicity, and 3‐D intrinsic chiral net was chosen as stationary phase to prepare Ni(D‐cam)(H2O)2‐coated open tubular columns for high‐resolution gas chromatographic (GC) separation. Two fused‐silica open tubular columns with different inner diameters and lengths, including column A (30 m × 250 µm i.d.) and column B (2 m × 75 µm i.d.), were prepared via a dynamic coating method. The chromatographic properties of the two columns were investigated using n‐dodecane as the analyte at 120 °C. The number of theoretical plates (plates/m) of the two metal–organic framework (MOF) columns was 1300 and 2750, respectively. The racemates, isomer and linear alkanes mixture were used as analytes for evaluating the separation properties of Ni(D‐cam)(H2O)2‐coated open tubular columns. The results showed that the columns offered good separations of isomer and linear alkanes mixture, especially racemates. Chirality 26:27–32, 2013. © 2013 Wiley Periodicals, Inc.
Simulation of Reaction Integrated Adsorption of Trienzymatic Synthesized Laminaribiose
Authors: Waluga Thomas , Zein Marwan , Jördening Hans‐Joachim , Scholl Stephan 
Published: November 2013

AbstractAusgehend von drei individuellen enzymatischen Kinetiken sowie von Gleichgewichtsdaten aus Reinstoffmessungen wurde eine Simulation für die reaktionsintegrierte Adsorption von trienzymatisch produzierter Laminaribiose erstellt. Dabei steigert eine diskontinuierliche Überlagerung von Reaktion und Adsorption die Ausbeute um ein Drittel. Für eine kontinuierliche Adsorption mit zyklischem Ausschleusen des beladenen und Ersatz durch frisches Adsorbens lässt sich die Ausbeute sogar um das 2,4fache steigern. Ein zu kurzer Austauschzyklus des Adsorbens führt jedoch zum Austrag von Intermediaten, so dass weniger Produkt gebildet wird.
Development of Solubility Selective Mixed Matrix Membranes for Gas Separation
Authors: Mushardt Heike , Kramer Verena , Hülagü Deniz , Brinkmann Torsten , Kraume Matthias 
Published: November 2013

AbstractA new kind of gas permeation membrane is developed to separate higher hydrocarbons (C3+) from permanent gases. State of the art for such gas permeation applications are membranes based on solubility selective, rubbery polymers, which offer high permeances but relatively low selectivities. The new membrane is designed to improve selectivity, and therefore, significantly reduce energy demand and size of a gas separation plant. The membrane is based on the mixed matrix concept and consists of a rubbery polymer matrix with incorporated activated carbon particles. This two phase separation layer forms a solubility selective mixed matrix membrane by combining the advantages of both materials. The separation of n‐C4H10/CH4 mixtures is investigated. Based on experimental results a new concept for a transport model for mixed matrix membrane is introduced.
Taxol in ovarian cancer
Authors: Runowicz Carolyn D. , Wiernik Peter H. , Einzig Avi I. , Goldberg Gary L. , Horwitz Susan B. 
Published: November 2013

AbstractTaxol is a structurally complex natural plant product with a novel mechanism of action. The supply of this drug is limited by its low abundance in the bark of the slow‐growing yew tree from which it is extracted. The chemical complexity of taxol has hampered the development of a feasible process to synthesize large quantities. Analogues are being made from a precursor found in the needles of the yew tree. However, there is a need to develop a more efficient method to provide adequate supplies of this drug. This review article summarizes the preclinical and clinical studies of taxol in ovarian cancer. Phase I studies have identified the drug's toxicities. Neutropenia has been the dose‐limiting toxicity in most trials, and premedications and longer infusion schedules have been used to reduce the incidence and severity of hypersensitivity reactions. The intraperitoneal administration of taxol in Phase I studies showed a pharmacologic advantage with acceptable toxicity. Its activity in ovarian cancer was noticed first in Phase I trials at the Albert Einstein College of Medicine and Johns Hopkins University. These observations led to Phase II testing, which documented response rates of 20–35% in patients with relapsed or refractory ovarian cancer. Phase III trials of taxol and cisplatin versus cyclophosphamide and cisplatin in untreated patients with ovarian cancer are in progress. Studies combining taxol with colony‐stimulating factors and cisplatin are ongoing. Taxol is an important new drug in ovarian cancer. Its unique mechanism of action and toxicities make it an attractive agent to use in combination with currently active drugs. Future studies will determine the role of taxol in the management of this disease, but the widespread availability of this drug will depend on the development of a feasible synthetic process.
Strain‐Engineered Modulation on the Electronic Properties of Phosphorous‐Doped ZnO
Authors: Lu Ying‐Bo , Dai Ying , Wei Wei , Zhu Yingtao , Huang Baibiao 
Published: November 2013

AbstractThe modulation of strain on the electronic properties of ZnO:P is investigated by density functional theory calculations. The variation of formation energy (Ef) and band structure with strains ranging from −0.1 to 0.1 are considered. Although both the conduction band minimum (CBM) and the valence band maximum of ZnO are antibonding states, the CBM is more sensitive to strain, reducing the band gap with an increase in strain. P‐substituted O (PO) defects show poor p‐type conductivity due to a smaller Ef and lower lying acceptor levels as a consequence of lattice expansion. The Ef of P‐substituted Zn (PZn) defects decreases under tension, owing to the release of strong repulsive stress induced by excess electrons from PZn. The donor energy band of PZn broadens under tensile strain, which benefits n‐type conductivity. For Zn vacancies (VZn) and PZn–2VZn complexes, the distances between the O atoms around VZn are so large that repulsive and attractive interactions become weak, which results in an easy release of the strain. We herein present for the first time that the Ef values of VZn and PZn–2VZn complexes decrease under both tension and compression, or in the high‐pressure rock‐salt phase. Under a strain of 0.1 the PZn–2VZn complex shows the smallest Ef. Under −0.07 strain the wurtzite/rock‐salt phase transition occurs and the direct band gap becomes an indirect one. The variation of band structures in the rock‐salt phase is similar to that in the wurtzite phase. Consequently, the p‐type conductivity of ZnO:P can be improved with an increase in solubility of PZn–2VZn or VZn defects.
A Rapid Freeze‐Quench Setup for Multi‐Frequency EPR Spectroscopy of Enzymatic Reactions
Authors: Pievo Roberta , Angerstein Brigitta , Fielding Alistair J. , Koch Christian , Feussner Ivo , Bennati Marina 
Published: November 2013

AbstractElectron paramagnetic resonance (EPR) spectroscopy in combination with the rapid freeze‐quench (RFQ) technique is a well‐established method to trap and characterize intermediates in chemical or enzymatic reactions at the millisecond or even shorter time scales. The method is particularly powerful for mechanistic studies of enzymatic reactions when combined with high‐frequency EPR (ν≥90 GHz), which permits the identification of substrate or protein radical intermediates by their electronic g values. In this work, we describe a new custom‐designed micro‐mix rapid freeze‐quench apparatus, for which reagent volumes for biological samples as small as 20 μL are required. The apparatus was implemented with homemade sample collectors appropriate for 9, 34, and 94 GHz EPR capillaries (4, 2, and 0.87 mm outer diameter, respectively) and the performance was evaluated. We demonstrate the application potential of the RFQ apparatus by following the enzymatic reaction of PpoA, a fungal dioxygenase producing hydro(pero)xylated fatty acids. The larger spectral resolution at 94 GHz allows the discernment of structural changes in the EPR spectra, which are not detectable in the same samples at the standard 9 GHz frequency.
Spectroscopic Properties and Upconversion Studies in Ho3+/Yb3+ Co‐doped Calcium Scandate with Spectrally Pure Green emission
Authors: Li Jing , Zhang Jiahua , Hao Zhendong , Zhang Xia , Zhao Jihong , Luo Yongshi 
Published: November 2013

AbstractThe optical properties of a Ho3+/Yb3+ co‐doped CaSc2O4 oxide material are investigated in detail. The spectral properties are described as a function of doping concentrations. The efficient Yb3+→Ho3+ energy transfer is observed. The transfer efficiency approaches 50 % before concentration quenching. The concentration‐optimized sample exhibits a strong green emission accompanied with a weak red emission, showing perfect green monochromaticity. The results of the spectral distribution, power dependence, and lifetime measurements are presented. The green, red, and near‐infrared (NIR) emissions around 545, 660, and 759 nm are assigned to the 5F4+5S2→5I8, 5F5→5I8, and 5F4+5S2→5I7 transitions of Ho3+, respectively. The detailed study reveals the upconversion luminescence mechanism involved in a novel Ho3+/Yb3+ co‐doped CaSc2O4 oxide material.