bluuebunny/crossref_metadata_2025_split huggingface dataset:
Who is Subjected to Coercive Measures as a Psychiatric Inpatient? A Multi-Level Analysis
Authors: Flammer E , Steinert T , Eisele F , Bergk J , Uhlmann C 
Published: July 2013

Background:
For a reduction in the use of coercive interventions it will be necessary to identify patients at risk. The aim of this study was to explore the impact of basic patient characteristics at admission, history within 24 hours before admission, and living conditions on the risk of experiencing coercive measures, controlling for ward characteristics in a multi-level approach.

Methods:
Patient characteristics of 3389 patients (1920 women) who had received inpatient treatment in 2007, data relating to coercive measures, and ward characteristics were extracted from the clinical basic documentation.

Results:
Patients with aggressive behaviour in the 24 hours prior to admission had a three times higher risk of coercive measures compared to non-aggressive patients. Severity of illness increased the risk of coercion markedly. With each level of severity, the risk of coercion was doubled. Voluntariness of stay appeared to be the best protective factor against coercive measures. If a patient stayed voluntarily, this reduced the risk of coercion by more than two thirds. No impact was found for living conditions.

Conclusions:
To identify patients at risk, it is most important to intensively monitor patients with aggressive behaviour prior to admission and patients with a greater severity of psychopathological symptoms.
Physical Activity in Depressed Elderly. A Systematic Review
Authors: Mura Gioia , Carta Mauro Giovanni 
Published: July 2013

Background:exercise may reduce depressive symptoms both in healthy aged populations and in old patients diagnosed with MDD, but few specific analysis were conducted on the efficacy of exercise as an adjunctive treatment with antidepressants, which may be probably more useful in clinical practice, considered the high prevalence of treatment resistant depression in late life, the low cost and safety of physical activity interventions.Objective:to establish the new findings on the effectiveness of exercise on depression in elderlies, with particular focus on the efficacy of the exercise as an adjunctive treatment with antidepressants drug therapy.Method:the search of significant articles was carried out in PubMed/Medline with the following key words: “exercise”, “physical activity”, “physical fitness”, “depressive disorder”, “depression”, “depressive symptoms”, “late life”, “old people”, and “elderly”.Results:44 papers were retrieved by the search. Among the 10 included randomized controlled trials, treatment allocation was adequately conceived in 4 studies, intention-to-treat analysis was performed in 6 studies, but no study had a double-blinded assessment. We examined and discussed the results of all these trials.Conclusion:in the last 20 years, few progresses were done in showing the efficacy of exercise on depression, due in part to the persistent lack of high quality research, in part to clinical issues of management of depression in late life, in part to the difficult to establish the real effectiveness of exercise on depressive symptoms in elderlies. However, there are some promising findings on physical activity combined with antidepressants in treatment resistant late life depression.
Comorbidity of Depression and Anxiety: Association with Poor Quality of Life in Type 1 and 2 Diabetic Patients
Authors: de Ornelas Maia Ana Claudia C. , Braga Arthur de Azevedo , Paes Flávia , Machado Sergio , Carta Mauro Giovanni , Nardi Antonio Egidio , Silva Adriana Cardoso 
Published: July 2013

Background:Diabetes is associates with depression and impairment in Quality of Life (QoL).Objective:The objective is to define the frequencies of depressive and anxiety symptoms in a sample of patients diagnosed with type 1 and 2 diabetes, the amount of impairment of QoL and the weight of depression and anxiety in determining the QoL in such of patients.Methods:A total of 210 patients were divided into two groups (type 1 and type 2). Patients completed the HADS and WHOQoL-bref.Results:Groups showed a high prevalence of anxiety (type 1 = 60%, type 2 = 43.8%) and depression (type 1 = 52.4%, type 2 = 38.1%), both measures were significantly higher (p < 0.05) in diabetes type 1 patients. Type 1 patients also showed a QoL in the overall assessment and the physical, psychological and social relations domains. In both Type 1 and 2 diabetes poor QoL was found associated by anxiety and depression comorbidity.Conclusion:In overall diabetes patients depression and anxiety seems to be a determinant of poor QoL.
Impact of Blood Cultures on the Changes of Treatment in
Hospitalized Patients with Community-Acquired
Pneumonia
Authors: Ishikawa Genta , Nishimura Naoki , Kitamura Atsushi , Yamano Yasuhiko , Tomishima Yutaka , Jinta Torahiko , Chohnabayashi Naohiko 
Published: July 2013

Background:
Initial blood cultures (BCs) with severe community-acquired pneumonia (CAP) are warranted. However, other than severity, the specific contributing factors that affect the decision to change antimicrobial agents have not been evaluated previously.

Methods:
Consecutive adults with CAP hospitalized between January 2008 and December 2010 were assessed retrospectively. We enrolled those who were over 18 years old with typical symptoms of pneumonia and with an infiltrate consistent with pneumonia, from which 2 sets of BCs were obtained. Those who had been immunocompromised, hospitalized, or prescribed antibiotics in the past 30 days were excluded. We retrospectively assessed the factors contributing to the change in antimicrobial agents as well as the frequency of these changes in the enrolled patients based on the initial BC results.

Results:
In total, 793 patients with initial diagnosis of CAP were admitted; 399 met the inclusion criteria. Among them, 386 were made definitive diagnosis of CAP after admission (the remaining 13 were made alternative diagnosis [non-pneumonia illnesses]). BC results were positive in 17 (4.4%) out of 386 CAP patients, among whom antimicrobial therapy was changed based on the BC results in 8 (2.1%) (Pneumonia Severity Index [PSI] grade IV; 2, PSI grade V; 6). Alternative diagnosis after admission was contributing factors for changing antimicrobial agents based on the positive blood culture results.

Conclusions:
The use of BCs should be limited to patients with very severe cases. It would be helpful to find alternative diagnosis and modify treatment.
Are Capitalized Software Development Costs Informative About Audit Risk?
Authors: Krishnan Gopal V. , Wang Changjiang (John) 
Published: July 2013

SYNOPSIS
Capitalization of software research and development costs (SDC) under SFAS No. 86 is the only exception to SFAS No. 2 that calls for immediate expensing of R&D costs. Although intangible assets have become increasingly relevant for firm valuation, they remain largely unexplored in audit research. This is an important topic because intangible assets, especially those that are internally developed, pose greater challenges in assessing audit risk relative to tangible assets. Capitalization of SDC offers a unique opportunity to study how auditors assess audit risk associated with the recognition of this intangible asset. While capitalized SDC could shed light on software products' potential commercial success and inform the auditor about the client's business risk, the accounting flexibility allowed by SFAS No. 86 also increases the risk of earnings management, and thus implies higher audit risk. Using audit fees as a proxy for audit risk, our results indicate that capitalized SDC are negatively associated with audit fees for firms where capitalization is inconsequential to beating analysts' forecasts, and also for firms with low analysts' following. These results support the notion that capitalized SDC signal lower business risk, especially for firms with low earnings management risk or high private information.
Two New Fissidens Species (Fissidentaceae) from Tropical Eastern Africa and Fissidens Bessouensis Corb., a Remarkable Species with Fimbriate Leaves and Multicellular Spores
Authors: Bruggeman-Nannenga Maria Alida 
Published: July 2013

Abstract Fissidens acrophilus Bruggeman-Nannenga, sp. nov. (subgenus Fissidens) from Kenya and Uganda and F. obscurifrons Bruggeman-Nannenga, sp. nov. (subgenus Fissidens?) from Tanzania are newly described and figured. F. obscurifrons is compared to the little known Madeiran F. nobreganus Luisier & P. de la Varde. A revision of F. bessouensis Corb. (subgenus Octodiceras) with description, diagnosis and figures and a discussion including adaptations to an aquatic habitat is presented. Multicellular spores and fimbriate leaf margins are reported in the Fissidentaceae for the first time. Rectification: F. angustelimbatus Mitt. is eliminated from the African flora.
Lejeunea Subelobata and Lejeunea Drummondii (Jungermanniopsida) in Australasia
Authors: Renner Matt A. M. 
Published: July 2013

Abstract Lejeunea subelobata Carrington & Pearson has been regarded as a synonym of L. drummondii Taylor, but the two species differ in patterns of variation in lobule morphology, shapes of the gynoecial bracteole, female bract underleaf and vegetative underleaves; in stem anatomy, and ecology. Lejeunea subelobata is a rheophyte from south-east Australia, Tasmania, and New Zealand that grows primarily as a lithophyte on rock within and around waterways, in association with basicolous substrates particularly basalt, rhyolite and andesite. Lobules in L. subelobata are always explanate, the female bract underleaf is obovate, underleaves are rotund and remote, and the stem medulla has 19-26 cells with small concave trigones. Lejeunea drummondii is, in its current circumscription, an ecologically and morphologically malleable taxon confined to Australia. The relationship between L. drummondii and plants from New Zealand described as L. epiphylla Colenso nom. illeg. requires further investigation.
New and Noteworthy Records of Mosses from Doi (Mt.) Inthanon, Chiang Mai, Chom Tong District, Northern Thailand
Authors: Printarakul Narin , Tan Benito C. , Santanachote Kanya , Akiyama Hiroyuki 
Published: July 2013

Abstract Mosses new to Thailand (35 species in 29 genera) and new to Doi Inthanon (6 species in 6 genera) are reported based on collections made by the authors. Austinia tenuinervis var. micholitzii W. R. Buck & H. A. Crum, Brotherella nictans (Mitt.) Broth., Chionostomum hainanensis B. C. Tan & Y. Jia, Clastobryopsis muelleri (Dixon) Tixier, Trichosteleum stigmosum Mitt., Micralsopsis complanata (Dixon) W. R. Buck, and Fissidens schwabei Nog. are fully illustrated.
A New Moss Checklist of Negara Brunei Darussalam
Authors: Tan Benito C. , Mohamed Haji 
Published: July 2013

Abstract A new moss checklist with updated nomenclature is given for the small country of Brunei Darussalam located in the northern part of Borneo. A total of 103 species in 50 genera are now collected and reported. The country’s moss flora is still very much undercollected, judging from our present results: (i) the absence of cosmopolitan and common paleotropical species such as Bryum apiculatum Schwägr., Callicostella papillata (Mont.) Mitt., Funaria hygrometrica Hedw., Isopterygium minutirameum (Müll. Hal.) A. Jaegr., Octoblepharum albidum Hedw. and Philonotis hastata (Duby) Wijk & Margad.; (ii) the absence of widespread families such as Pottiaceae and Ditrichaceae; and (iii) the under-representation of speciose genera such as Ectropothecium, Macromitrium, Thuidium and Trichosteleum, with only one species collected. The incompleteness of our knowledge of the moss flora makes it impossible to assess the country’s endangered moss species.
Do Male and Female Plants Display Different Haplotype Patterns in the Moss Drepanocladus Trifarius (Bryophyta, Amblystegiaceae)?
Authors: Hedenäs Lars , Bisang Irene 
Published: July 2013

Abstract The moss Drepanocladus trifarius (F. Weber & D. Mohr) Broth. ex Paris was used as a model species for a first evaluation of whether male and female haplotype patterns based on a combination of the nuclear molecular markers ITS and gpd, and the chloroplast rpl16 are congruent or not. In 23 female and 23 male shoots from specimens sampled in Northern and Central Europe, sex was determined either by the presence of sexual branches or by a recently developed molecular marker. Analysis of molecular variance (AMOVA) showed that a small (6%) and almost significant (p = 0.066) fraction of the variation within the data is due to differences between the genders and that the haplotype diversity is higher among females than among males. No significant differences in haplotype variation were found among geographical regions. The near significant differences between females and males, despite low variation in ITS and rpl16, in this first study ever of potential differences in haplotype variation between genders of dioecious mosses suggests that further investigations of more specimens and more variable molecular markers should be performed. Such studies could potentially reveal patterns of relevance to understanding, for example, immigration routes and to pin-point refugial areas of different significance to the respective genders.
The Bryophyte Diversity of Ljubljana (Slovenia)
Authors: Skudnik Mitja , Sabovljević Aneta , Batič Franc , Sabovljević Marko 
Published: July 2013

Abstract.The authors studied the bryophyte flora of the city of Ljubljana (Slovenia), recording 104 bryophyte taxa within the inner ring-road of Ljubljana. The specimens were collected from randomly picked sampling sites during different seasons in 2011 and 2012. Interesting records include Barbula convoluta var. commutata (Jur.) Husn., Grimmia trichophylla Grev., Leptobryum pyriforme (Hedw.) Wilson, Phascum cuspidatum Hedw. and Pseudocrossidium hornschuchianum (Schultz) R. H. Zander, species last recorded in Slovenia more than 60 years ago. Some species rare and endangered in Slovenia were also recorded: Syntrichia papillosa (Willson) Jur. and Lunularia cruciata (L.) Lindb. Rhynchostegium rotundifolium (Scop. ex Brid.) Schimp., a moss red-listed Europea-wide, was recorded in the investigated area.
L'hospitalité, une valeur universelle ?
Authors: Dufourmantelle Anne 
Published: July 2013

On peut prendre pour exemple de valeur universelle « l’hospitalité » telle que Derrida nous a aidé à la penser, en montrant comment l’exigence d’hospitalité inconditionnelle doit être mise en rapport avec les conditions d’hospitalité qui définissent les sociétés de droit et leurs échanges. La psychanalyse, en ce sens, est une pratique de l’hospitalité, pas seulement à la folie, mais à la nuit qui nous habite. C’est une ouverture non seulement à l’inconnu mais à un possible désentravement. L’altérité rencontrée dans cet événement est une réserve de liberté et d’accomplissement, nécessaire au surgissement de l’inattendu.
Seul le particulier...
Authors: Blévis Jean-Jacques 
Published: July 2013

Ce texte interroge l’apport spécifique de l’analyse quant à l’approche de l’universel. Le transfert poussé à son point de chute de la croyance en un sujet supposé savoir produit un autre savoir qui, du plus particulier du symptôme, ouvre à une subjectivation paradoxale. De rares rencontres avec certaines œuvres d’art donnent à vivre une expérience très proche de celle-ci : j’évoque comment un film comme Shoah fut pour moi une expérience du même ordre, où la ruine de toute croyance va jusqu’à confronter à l’incroyable même.
Le cinquième élément et la « docte ignorance »
Authors: Cazenave Michel 
Published: July 2013

La médecine ayur-védique loin de soigner seulement le corps conduit à une capacité de méditation de l’âme. En tant que théologie mystique, elle a des racines communes avec la pensée grecque. De Aristote à Plotin, et jusqu’à Nicolas de Cues, elle suppose un principe premier, inconnaissable par la seule raison. Ce 5 e élément, dans l’organisation du monde, en assure l’unité « éthérée ».
Editorial to the Special Issue
Authors: Hein Eckhard , Niechoj Torsten , Truger Achim 
Published: July 2013

First paragraph
The world economy is presently suffering from the most severe economic crisis since the Great Depression in the early 1930s. As by now seems to be obvious, the present financial crisis, massive state intervention in the financial markets in order to prevent a melt-down, and fiscal stimulus packages inconceivable even several months ago, mark the failure of an economic policy agenda which might be called ›neo-Liberalism‹. This agenda, broadly speaking, focussed on the deregulation of financial, labour and goods markets and on minimising state intervention. It meant a massive redistribution of income and wealth at the expense of labour and ordinary households, increasing imbalances on the global level and rising financial fragility. The failure of this policy agenda is also a failure of mainstream economic theory which has supported it. In particular those theories which are based on the confidence and firm belief that free markets will be stable and generate a full employment equilibrium – at least in the long run – and that the only role left for macroeconomic policies, in particular monetary policies, is to facilitate and accelerate the adjustment process towards this equilibrium, as for example in the dominating New Consensus Model (NCM), have failed.
Identification of Trichomonas vaginalis in Different Papanicolaou Test Preparations: Trends Over Time in the College of American Pathologists Educational Interlaboratory Comparison Program
Authors: Howell Lydia Pleotis , Darragh Teresa M. , Souers Rhona J. , Thomas Nicole , Moriarty Ann T. 
Published: July 2013

Context.—The College of American Pathologists' Interlaboratory Comparison Program in Gynecologic Cytology has seen an increase in enrollment in liquid-based Papanicolaou test challenges with a decrease for conventional Papanicolaou tests. Trichomonas vaginalis can be difficult to identify in all preparation types.Objectives.—To evaluate 20 years of participant results from the College of American Pathologists Interlaboratory Comparison Program in Gynecologic Cytology for Trichomonas to ascertain whether performance has changed because of the introduction of liquid-based Papanicolaou and proficiency testing.Design.—Concordance rates for the target diagnosis of Trichomonas vaginalis were evaluated for 167 956 participant responses (1990–2010). A nonlinear mixed model was fit with participant type, preparation type, and a 2-level program year (1990–2005 and 2006–2010) reflecting before and after proficiency testing began. A repeated-measures component allowed modeling of the slide-specific performance to ensure that the overall results were not based on the performance of a few slides.Results.—Cytotechnologists had higher concordance with the target diagnosis than did pathologists (89.8% [72 992 of 81 319] versus 83.4% [72 271 of 86 637], P &lt; .001) and better performance for each preparation type (P = .003). Concordance initially dropped after the introduction of proficiency testing (P &lt; .001) for conventional and liquid-based (SurePath) preparations by both participant types, followed by quick, parallel improvement.Conclusions.—Performance is high in the detection of Trichomonas vaginalis in the College of American Pathologists Interlaboratory Comparison Program in Gynecologic Cytology. Liquid-based Papanicolaou and proficiency testing minimally affected participant performance. Cytotechnologists performed better over time and across preparation types than did pathologists, although pathologists showed performance results parallel to that of the cytotechnologists. Awareness of the performance differences by pathologists and cytotechnologists, as well as their difference in proficiency among liquid-based techniques, may help ensure accurate results in clinical practice.
High-Risk Human Papillomavirus DNA Detected in Primary Squamous Cell Carcinoma of Urinary Bladder
Authors: Chapman-Fredricks Jennifer Rose , Cioffi-Lavina Maureen , Accola Molly A. , Rehrauer William M. , Garcia-Buitrago Monica T. , Gomez-Fernandez Carmen , Ganjei-Azar Parvin , Jordà Mercè 
Published: July 2013

Context.—We reported previously that more than one-third (37%) of primary bladder squamous cell carcinomas (SCCs) demonstrate diffuse p16 immunoreactivity independent of gender. This observation made us question whether p16 overexpression in bladder carcinoma is due to human papillomavirus (HPV)–dependent mechanisms.Objectives.—To determine whether the presence of high-risk HPV (HR-HPV) DNA could be detected in these tumor cells.Design.—Fourteen cases of primary bladder SCC, which were positive for p16 by immunohistochemistry, were probed for the detection of HR-HPV by in situ hybridization and the signal amplification Invader assay. Samples positive for detection of HR-HPV by Invader assay were amplified by using HR-HPV type-specific primers, and amplification products were DNA sequenced.Results.—Detection of HR-HPV by the in situ hybridization method was negative in all cases (0 of 14). However, in 3 of 14 cases (21.4%), the presence of HR-HPV DNA was detected with the Cervista HPV HR Invader assay, which was followed by identification of genotype. All positive cases were confirmed by using HR-HPV type-specific amplification followed by DNA sequencing. Identified HR-HPV genotypes included HPV 16 (2 cases) and HPV 35 (1 case).Conclusions.—High-risk HPV DNA is detectable in a subset of primary bladder SCCs. Based on the well-documented carcinogenic potential of HR-HPV, there is a necessity for additional studies to investigate the role of HR-HPV in bladder carcinogenesis.
Marginal and Joint Distributions of S100, HMB-45, and Melan-A Across a Large Series of Cutaneous Melanomas
Authors: Viray Hollis , Bradley William R. , Schalper Kurt A. , Rimm David L. , Rothberg Bonnie E. Gould 
Published: July 2013

Context.—The distribution of the standard melanoma antibodies S100, HMB-45, and Melan-A has been extensively studied. Yet, the overlap in their expression is less well characterized.Objectives.—To determine the joint distributions of the classic melanoma markers and to determine if classification according to joint antigen expression has prognostic relevance.Design.—S100, HMB-45, and Melan-A were assayed by immunofluorescence-based immunohistochemistry on a large tissue microarray of 212 cutaneous melanoma primary tumors and 341 metastases. Positive expression for each antigen required display of immunoreactivity for at least 25% of melanoma cells. Marginal and joint distributions were determined across all markers. Bivariate associations with established clinicopathologic covariates and melanoma-specific survival analyses were conducted.Results.—Of 322 assayable melanomas, 295 (91.6%), 203 (63.0%), and 236 (73.3%) stained with S100, HMB-45, and Melan-A, respectively. Twenty-seven melanomas, representing a diverse set of histopathologic profiles, were S100 negative. Coexpression of all 3 antibodies was observed in 160 melanomas (49.7%). Intensity of endogenous melanin pigment did not confound immunolabeling. Among primary tumors, associations with clinicopathologic parameters revealed a significant relationship only between HMB-45 and microsatellitosis (P = .02). No significant differences among clinicopathologic criteria were observed across the HMB-45/Melan-A joint distribution categories. Neither marginal HMB-45 (P = .56) nor Melan-A (P = .81), or their joint distributions (P = .88), was associated with melanoma-specific survival.Conclusions.—Comprehensive characterization of the marginal and joint distributions for S100, HMB-45, and Melan-A across a large series of cutaneous melanomas revealed diversity of expression across this group of antigens. However, these immunohistochemically defined subclasses of melanomas do not significantly differ according to clinicopathologic correlates or outcome.