bluuebunny/crossref_metadata_2025_split huggingface dataset:
Antifouling ultrafiltration membrane fabricated from poly (arylene ether ketone) bearing hydrophilic hydroxyl groups
Authors: Zhu Jianhua , Zheng Jifu , Zhang Qifeng , Zhang Suobo 
Published: September 2015

ABSTRACTA new kind of membrane formation polymer, cardo poly(arylene ether ketone) bearing hydrophilic hydroxyl groups (PEK‐OH) was synthesized from the biphenol monomer 2‐(2‐hydroxyethyl)‐3, 3‐bis (4‐hydroxyphenyl)‐isoindolin‐1‐one (PPH‐OH), and 4, 4′‐difluorodiphenylketone. PEK‐OH asymmetric ultrafiltration membranes were prepared using the immersion coagulation phase inversion method. The PEK‐OH membrane prepared using the optimized conditions exhibited a pure water flux of 516 ± 18 L·m−2·h−1 and a 99.1 ± 1.4% rejection of bovine serum albumin (BSA) at an operating pressure of 0.1 MPa. The contact angle of PEK‐OH membrane was 66.0 ± 2.4 lower than these of the PEK‐C membrane (87.0 ± 2.8°, prepared from polymer PEK‐C under the same membrane formation condition as PEK‐OH membrane) and the UE50 membrane (84.0 ± 1.6°, a commercial PES ultrafiltration membrane). The amount of BSA protein adsorbed to the PEK‐OH membrane under static condition was measured to be 3.12 μg·cm−2, which was greatly lower than that of 88.71 μg·cm−2 and 74.40 μg·cm−2 for the PEK‐C and the UE50 ultrafiltration membranes, respectively. Under dynamic filtration of BSA experiments, the PEK‐OH ultrafiltration membrane showed a 78.3% water flux recovery ratio, while only a 39.7% for the PEK‐C membrane and 46.5% for UE50 membrane were detected in the first cycle. After three cycles of BSA and LYZ filtration, the flux recovery ratio of PEK‐OH ultrafiltration membrane changed to be stable at 75% and 73%, while that of PEK‐C and UE50 ultrafiltration membranes remained declining gradually. Thus, hydrophilic PEK‐OH improves antifouling membrane property. © 2015 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2016, 132, 42809.
Modeling and simulation of fiber‐reinforced polymer mold‐filling with phase change
Authors: Wang Fang , Li Junlin , Yang Binxin 
Published: September 2015

ABSTRACTA gas‐solid‐liquid three‐phase model for the simulation of fiber‐reinforced composites mold‐filling with phase change is established. The influence of fluid flow on the fibers is described by Newton's law of motion, and the influence of fibers on fluid flow is described by the momentum exchange source term in the model. A revised enthalpy method that can be used for both the melt and air in the mold cavity is proposed to describe the phase change during the mold‐filling. The finite‐volume method on a non‐staggered grid coupled with a level set method for viscoelastic‐Newtonian fluid flow is used to solve the model. The “frozen skin” layers are simulated successfully. Information regarding the fiber transformation and orientation is obtained in the mold‐filling process. The results show that fibers in the cavity are divided into five layers during the mold‐filling process, which is in accordance with experimental studies. Fibers have disturbance on these physical quantities, and the disturbance increases as the slenderness ratio increases. During mold‐filling process with two injection inlets, fiber orientation around the weld line area is in accordance with the experimental results. At the same time, single fiber's trajectory in the cavity, and physical quantities such as velocity, pressure, temperature, and stresses distributions in the cavity at end of mold‐filling process are also obtained. © 2015 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2016, 133, 42881.
The physical perspective on the solid and molten states associated with the mechanical properties of eco‐friendly HDPE/Pinus taeda wood‐plastic composites
Authors: Grison Karine , Pistor Vinicius , Scienza Lisete Cristine , Zattera Ademir José 
Published: September 2015

ABSTRACTThe manufacture of wood plastic composites (WPCs) by reutilizing post‐consumed polymeric materials and post‐industry wood wastes contributes to reduce the environmental impact and the consumption of virgin plastics. In this work, the influence of interfacial adhesion on the solid and molten states of high density polyethylene (HDPE) containing WPCs wood dust of recycled Pinus taeda (PT) was evaluated. The composites were prepared by extrusion in a twin screw extruder using maleic anhydride as compatibilizer. The samples were analyzed by dynamic‐mechanical analysis (DMA), tensile and impact strength measurements, oscillatory rheometry, differential scanning calorimetry (DSC) and scanning electron microscopy (SEM). DMA analysis showed increase in module and an improved interface with physical interaction between the WPCs phases. The higher molecular interactivity interface improved the mechanical properties relative to pure HDPE. Melting state analysis showed increased WPCs flow restriction, this feature being correlated with reduction in the molecular degree of freedom during flow, which consequently reduces the crystalline degree changes in microstructure as well as in processing parameters of the material. These results lead to consider the development of an eco‐friendly and economic effective technology to reuse abundant recycled solid wastes in a new market. © 2015 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2016, 133, 42887.
Complex aggregates formed with a hyperbranched polyglycerol derivative for drug delivery
Authors: Zheng Qianqian , Zhou Xiaoyan , Li Hui , Ma Dong , Xue Wei 
Published: September 2015

ABSTRACTAn amphiphilic hyperbranched polyglycerol derivative (HPG‐C18) was synthesized by the anionic ring‐opening copolymerization with glycidol and 1,2‐epoxyloctadecane as the monomers. This hyperbranched polymer formed large complex aggregates as confirmed by dynamic light scattering and transmission electron microscopy tests. Because of its amphiphilic properties, HPG‐C18 was explored to load hydrophobic docetaxel, a clinical antitumor drug, and deliver it into breast cancer cell line (MCF‐7) cells. To investigate the application of the aggregates in drug delivery, blood compatibility was studied by hemolysis analysis, red blood cell observation, and thromboelastography assay. These results indicate that HPG‐C18 inhibited MCF‐7 proliferation effectively with good blood compatibility, and this suggested a potential application in tumor therapy. © 2015 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2016, 133, 42895.
Thermal decomposition of diethyl ketone triperoxide in methyl methacrylate: Theoretical and experimental study of the initial solvation state and its influence on the polymerization process
Authors: Delgado Rodríguez Karla , Enríquez‐Medrano Francisco J. , Grande Daniel , Barreto Gastón P. , Cañizo Adriana , Eyler Nora , Merino Gabriel , Morales Graciela 
Published: September 2015

ABSTRACTThe decomposition rate constant (kd) of diethyl ketone triperoxide (DEKTP, 3,3,6,6,9,9‐hexaethyl‐1,2,4,5,7,8‐hexaoxacyclononane) in methyl methacrylate (MMA) was determined by the kinetic study of its thermal decomposition at temperatures from 110 to 140°C. The calculated kd for DEKTP in MMA was 2.4 times lower (at 130°C) compared with that previously determined and reported in styrene (St). Density functional theory (DFT) calculations demonstrated that the decomposition of DEKTP molecule in MMA required higher interaction energy than in St, thus explaining its lower kd value. Bulk polymerization kinetics of MMA using DEKTP as the initiator revealed the presence of an induction period, in contrast with St polymerization, providing clear evidence of the solvation state influence at early polymerization stages. This work provides mechanistic insights into the interactions among the multi‐functional cyclic peroxide DEKTP and vinyl monomers; St and MMA, and their influence on the polymerization kinetics. © 2015 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2016, 133, 42905.
Chemical surface coating of MWCNTs with riboflavin and its application for the production of poly(ester‐imide)/MWCNTs composites containing 4,4′‐thiobis(2‐tert‐butyl‐5‐methylphenol) linkages: Thermal and morphological properties
Authors: Mallakpour Shadpour , Soltanian Samaneh 
Published: September 2015

ABSTRACTIn this work, carboxylated multi‐walled carbon nanotubes (MWCNTs) were functionalized with riboflavin as a biological molecule under microwave irradiation. Solution blending method was used to incorporate different modified MWCNTs content (5, 10, and 15 wt %) into a chiral and biodegradable poly(ester‐imide) (PEI) to fabricate PEI‐based nanocomposites. The products were characterized for assessing the spectroscopic, thermal, and morphological properties by Fourier‐transform infrared spectroscopy, thermogravimetric analysis (TGA), X‐ray diffraction, transmission electron microscopy (TEM), and field‐emission scanning electron microscopy (FESEM). Optically active PEI was prepared by step‐growth polymerization of amino‐acid‐based diacid and aromatic diol. Functionalized MWCNTs were well dispersed in the PEI matrix and their distribution was homogeneous. This was confirmed by morphology study of the fractured surfaces of nanocomposites by FESEM and TEM. The addition of functionalized MWCNTs improved the thermal stability of NCs compared to the pure PEI. It was found from TGA data that temperature at 10% weight loss was increased from 409°C for pure PEI to 417, 420, and 424°C for nanocomposites containing 5, 10, and 15% functionalized MWCNTs, respectively. © 2015 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2016, 133, 42908.
Polyhedral oligomeric silsesquioxanes nanoreinforced methacrylate/epoxy hybrids
Authors: Lungu Adriana , Florea Nicoleta Mihaela , Manea Mihaela , Vasile Eugeniu , Iovu Horia 
Published: September 2015

ABSTRACTThe aim of this study was to design novel binary and ternary copolymers based on methacrylate and/or epoxy monomers reinforced with 10 wt % mono‐/octafunctional polyhedral oligomeric silsesquioxanes (POSS) compounds bearing one or eight epoxy or methacrylate moieties. The experimental parameters such as temperature and time of reaction, comonomer ratio and the incorporation of various types of POSS that strongly influences the curing behavior, polymerization kinetics, glass transition temperature (Tg), thermostability and morphological structure of the obtained copolymers were investigated through DSC, FTIR, DMA, TGA, and SEM techniques. The obtained results evidenced that the complex kinetic mechanisms of curing reactions for the binary and ternary copolymers ± POSS influence the thermomechanical and morphological properties of the materials. © 2015 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2016, 133, 42912.
Rheological properties of poly(lactic acid) based nanocomposites: Effects of different organoclay modifiers and compatibilizers
Authors: Acik Eda , Orbey Nese , Yilmazer Ulku 
Published: September 2015

ABSTRACTPoly(lactic acid) (PLA) nanocomposites containing five types of organically modified, layered silicates and two elastomeric compatibilizers, namely ethylene‐glycidyl methacrylate (E‐GMA) and ethylene‐butyl acrylate‐maleic anhydride (E‐BA‐MAH), were prepared using a twin screw extruder. The morphologies of the nanocomposites were determined by X‐ray diffraction (XRD) and transmission electron microscopy (TEM), and the rheological properties of the melts were measured using small‐amplitude oscillatory shear. XRD revealed that the addition of E‐GMA to the binary nanocomposites resulted in higher compatibility between the organoclay nanoplatelets and the polymer matrix. TEM showed that all of the nanocomposites contained mixed dispersed structures, involving tactoids of various sizes, as well as intercalated and exfoliated organoclay layers. Rheological properties were found to be affected by the differences in the compatibility between the organoclays and the polymer matrix, and by the addition of the compatibilizer. Organoclay types that resulted in high level of dispersion exhibited higher values of complex viscosity compared to that of neat PLA. The addition of E‐GMA introduced a solid‐like rheological behavior at low frequencies. All of the nanocomposites had similar rheological behavior at high frequencies. © 2015 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2016, 133, 42915.
The Effect of Dofetilide on the Heart Rate of GD11 and GD13 Rat Embryos, in vivo, Using Ultrasound
Authors: Ritchie Helen , Oakes Diana , Hung Tzong‐tyng , Hegedus Elizabeth , Sood Shreya , Webster William 
Published: September 2015

BACKGROUNDThere are a wide range of drugs including antidepressants, anticonvulsants and antipsychotics that cause embryonic bradycardia in vitro but it is unknown if they have a similar effect in vivo. One way to verify whether these in vitro findings are replicated in vivo is by the use of ultrasound examination of dosed pregnant rats. We tested this by examining the effect of dofetilide on embryonic heart rate (HR) in vivo using ultrasound.METHODSRats were dosed with dofetilide (4 or 2.5 mg/kg) on GD11 or (5 or 2.5 mg/kg) on GD13 and embryonic HR assessed by ultrasound, 2 and 24 hr later. Fetuses were examined for malformations on GD20.RESULTSHR of control rat embryos showed a wide range at each gestational day. Dosing with dofetilide on GD11 caused severe bradycardia (∼60% reduction) 2 hours after dosing with recovery after 24 h of >60% of LD but death and slow HR among the HD embryos. At term, 32% of the LD surviving fetuses had hypoplastic upper lip while >90% of HD embryos had died. On GD13, embryonic HR was reduced in a dose‐dependent manner with >85% of LD and HD recovered by 24 hr. At term, all LD fetuses were normal while 29% of HD fetuses had limb defects.CONCLUSIONSUltrasound is a useful technique to investigate the effect of maternally administered drugs on the embryonic HR in the rat. The results may provide more information about the safety of these drugs in pregnancy leading to better risk assessment for the human
Incorporating unnatural amino acids to engineer biocatalysts for industrial bioprocess applications
Authors: Ravikumar Yuvaraj , Nadarajan Saravanan Prabhu , Hyeon Yoo Tae , Lee Chong‐Soon , Yun Hyungdon 
Published: September 2015

AbstractThe bioprocess engineering with biocatalysts broadly spans its development and actual application of enzymes in an industrial context. Recently, both the use of bioprocess engineering and the development and employment of enzyme engineering techniques have been increasing rapidly. Importantly, engineering techniques that incorporate unnatural amino acids (UAAs) in vivo has begun to produce enzymes with greater stability and altered catalytic properties. Despite the growth of this technique, its potential value in bioprocess applications remains to be fully exploited. In this review, we explore the methodologies involved in UAA incorporation as well as ways to synthesize these UAAs. In addition, we summarize recent efforts to increase the yield of UAA engineered proteins in Escherichia coli and also the application of this tool in enzyme engineering. Furthermore, this protein engineering tool based on the incorporation of UAA can be used to develop immobilized enzymes that are ideal for bioprocess applications. Considering the potential of this tool and by exploiting these engineered enzymes, we expect the field of bioprocess engineering to open up new opportunities for biocatalysis in the near future.
Interactions between chensinin‐1, a natural antimicrobial peptide derived from Rana chensinensis, and lipopolysaccharide
Authors: Dong Weibing , Sun Yue , Shang Dejing 
Published: September 2015

ABSTRACTLipopolysaccharide (LPS) plays a critical role in the pathogenesis of sepsis caused by gram‐negative bacterial infections. Therefore, LPS‐neutralizing molecules would have important clinical applications. Chensinin‐1, a novel antimicrobial peptide with atypical structural features, was found in the skin secretions of the Chinese brown frog Rana chensinensis. To understand the role of LPS in the bacterial susceptibility to chensinin‐1 and to investigate its anti‐endotoxin effects, the interactions of chensinin‐1 with LPS were investigated in this study using circular dichroism, in situ IR, isothermal titration calorimetry, and zeta potential. This study is the first to use in situ IR spectroscopy to evaluate the secondary structural changes of this peptide. The capacity of chensinin‐1 to block the LPS‐dependent cytokine secretion of macrophages was also investigated. Our results show that chensinin‐1 can form α‐helical structures in LPS suspensions. LPS can affect the antimicrobial activity of chensinin‐1, and chensinin‐1 was able to mitigate the effects of LPS. These data may facilitate the development of antimicrobial peptides with potent antimicrobial and anti‐endotoxin activities. © 2015 Wiley Periodicals, Inc. Biopolymers 103: 719–726, 2015.
SOD2 genetic variant associated with treatment‐related ototoxicity in cisplatin‐treated pediatric medulloblastoma
Authors: Brown Austin L. , Lupo Philip J. , Okcu Mehmet Fatih , Lau Ching C. , Rednam Surya , Scheurer Michael E. 
Published: September 2015

AbstractManganese superoxide dismutase (MnSOD), encoded by the SOD2 gene, is involved in the detoxification of superoxide anion. Superoxide is likely a source of oxidative stress in the cochlea following treatment with platinum agents and radiation. Therefore, we examined SOD2 variants in association with ototoxicity among cisplatin‐treated childhood medulloblastoma patients. Blood samples were obtained from 71 eligible patients treated for pediatric medulloblastoma at Texas Children's Cancer Center (1987–2010). Ototoxicity was defined as requiring the use of a hearing aid sometime after the initiation of therapy. DNA was genotyped on the Illumina HumanOmni‐1 Quad BeadChip. A linkage disequilibrium (LD)‐based single‐nucleotide polymorphism (SNP) selection strategy was used to identify a minimal set of informative variants. Associations between SNPs and ototoxicity were assessed using logistic regression. Of the 71 eligible patients, 26 (37%) suffered from cisplatin‐related ototoxicity. Study participants were primarily male (73%) and non‐Hispanic white (42%). Five SOD2 variants (rs7855, rs5746151, rs5746136, rs2758331, and rs4880) identified by the LD‐based selection strategy were genotyped. After correcting for multiple comparisons, the C‐allele of the rs4880 variant was significantly associated with ototoxicity (odds ratio = 3.06, 95% confidence interval: 1.30–7.20) in adjusted models. The rs4880 T > C substitution results in a Val > Ala amino acid change at position 16 of the MnSOD mitochondrial targeting sequence. The Ala variant, which has been associated with increased MnSOD activity, was associated with hearing damage in this study. Platinum‐based therapies increase the expression of MnSOD, which may result in an abundance of hydrogen peroxide, a reactive oxygen species. Therefore, oxidative stress may be an important mechanism in therapy‐related cochlear damage.
ChemInform Abstract: Gallium Arsenate Dihydrate under Pressure: Elastic Properties, Compression Mechanism, and Hydrogen Bonding.
Authors: Spencer Elinor C. , Soghomonian Victoria , Ross Nancy L. 
Published: September 2015

AbstractCrystals of GaAsO4·2H2O are obtained as a minor product of the hydrothermal reaction of aqueous mixtures of VCl4, NaHAsO4, GaCl3, and guanidinium hydrochloride (autoclave, 456 K, 90 h) and characterized by high‐pressure single crystal XRD and Raman spectroscopy.
ChemInform Abstract: Reversible Electrochemical Intercalation of Aluminum in Mo6S8.
Authors: Geng Linxiao , Lv Guocheng , Xing Xuebing , Guo Juchen 
Published: September 2015

AbstractThe Chevrel phase Mo6S8 is prepared by reaction of CuCl2 and (NH4)2MoS4 in DMF (90 °C, 6 h) followed by heating of the precipitate in 5% H2/Ar atmosphere (1000 °C, 7 h).
ChemInform Abstract: Degradation Performance of a Keggin Type Zn—Mo—Zr Catalyst for Acidic Green B with Ultrasonic Waves.
Authors: Zhang Zhihong , Liao Zhipeng , Zhang Gehong 
Published: September 2015

AbstractNa6[Zn(Mo11ZrO39)]·20H2O with a Keggin structure of the 1:1:11 series is prepared by the classic acidification method using an aqueous Na2MoO4 solution at pH 6.5 to which aq.
ChemInform Abstract: Synthesis of BiVO4 via Oxidant Peroxo‐Method: Insights into the Photocatalytic Performance and Degradation Mechanism of Pollutants.
Authors: Lopes Osmando F. , Carvalho Kele T. G. , Macedo Gabriel K. , de Mendonca Vagner R. , Avansi Waldir Jr. , Ribeiro Caue 
Published: September 2015

AbstractBiVO4 is prepared from an equimolar aqueous solution of Bi(NO3)34 and NH4VO3 to which H2O2 is given in a 10:1 molar ratio.
ChemInform Abstract: Preparation, Crystal Structure, Vibrational Spectra, and Thermal Behavior of Tl2H2P2O6 and Tl4P2O6.
Authors: Wu Peng , Pook Niels‐Patrick , Gjikaj Mimoza 
Published: September 2015

AbstractThe new compounds (III) and (IV) are characterized by single crystal XRD, IR and Raman spectroscopy, and thermogravimetric measurements.
ChemInform Abstract: Trends in Syntheses, Structures, and Properties for Three Series of Ammine Rare‐Earth Metal Borohydrides, M(BH4)3·nNH3 (M: Y, Gd, and Dy).
Authors: Jepsen Lars H. , Ley Morten B. , Cerny Radovan Cerny Radovan , Lee Young‐Su , Cho Young Whan , Ravnsbaek Dorthe , Besenbacher Flemming , Skibsted Joergen , Jensen Torben R. 
Published: September 2015

AbstractSolvent‐ and halide‐free ammine rare earth metal borohydrates Ln(BH4)3·nNH3 (Ln: Y, Gd, Dy; n = 7, 6, 5, 4, 2, 1) are synthesized by combined mechanochemistry and solvent‐based metathesis reactions of LiBH4 and LnCl3 in the ratio of 3:1, followed by reaction of the produced Ln(BH4)3 with an excess of NH3 gas, yielding Ln(BH4)3·7NH3, that stepwise releases ammonia on thermal treatment.
ChemInform Abstract: Structural, Electrical, and Optical Properties of the Tetragonal, Fluorite‐Related Zn0.456In1.084Ge0.460O3.
Authors: Rickert Karl , Sedefoglu Nazmi , Malo Sylvie , Caignaert Vincent , Kavak Hamide , Poeppelmeier Kenneth R. 
Published: September 2015

AbstractZn0.456In1.084Ge0.460O3 is prepared by solid state reaction of ZnO, In2O3, and GeO2 (pellets in sacrificial powder in covered corundum crucible, 1250 °C, 16 h).
ChemInform Abstract: Zn(salen)‐Catalyzed Enantioselective Phenyl Transfer to Aldehydes and Ketones with Organozinc Reagent.
Authors: Shimizu Keisuke , Uetsu Hidenori , Gotanda Takashi , Ito Katsuji 
Published: September 2015

AbstractA chiral zinc salen complex is found to be a highly efficient catalyst for the enantioselective phenyl transfer of organozinc reagent to aromatic aldehydes and ketones.
ChemInform Abstract: Densely Substituted‐Proline Esters as Catalysts for Asymmetric Michael Additions of Ketones to Nitroalkenes.
Authors: Ruiz‐Olalla Andrea , Retamosa Maria de Gracia , Cossio Fernando P. 
Published: September 2015

AbstractFor the aldol reaction of cyclohexanone with perfluorobenzaldehyde both nitro and amino derivatives (I) are found to be active catalysts with similar stereoselectivity.
ChemInform Abstract: Enantioselective Lewis Acid Catalysis in Intramolecular [2 + 2] Photocycloaddition Reactions: A Mechanistic Comparison Between Representative Coumarin and Enone Substrates.
Authors: Brimioulle Richard , Bauer Andreas , Bach Thorsten 
Published: September 2015

AbstractThe photocycloaddition reactions of three coumarins and three dihydropyridones are investigated in the absence and in the presence of a Lewis acid.
ChemInform Abstract: An Unusual Formation of Diarylmethane Scaffolds from 4‐(Halomethyl)cyclohex‐2‐enone Derivatives.
Authors: Babu Kaki Raveendra , Khan Faiz Ahmed 
Published: September 2015

AbstractThis unusual dimerization of substrates (I) proceeds via a dehydrohalogenation/1,6‐conjugate addition/aromatization sequence.
ChemInform Abstract: Gold(I)/(III)‐Catalyzed Synthesis of Cyclic Ethers; Valency‐Controlled Cyclization Modes.
Authors: Morita Nobuyoshi , Yasuda Arisa , Shibata Motohiro , Ban Shintaro , Hashimoto Yoshimitsu , Okamoto Iwao , Tamura Osamu 
Published: September 2015

AbstractTwo types of cyclic ethers are obtained from propargylic alcohols by gold(I)/(III)‐catalyzed regiodivergent syntheses.