bluuebunny/crossref_metadata_2025_split huggingface dataset:
Simultaneous Defect Passivation and Co‐Catalyst Engineering Leads to Superior Photocatalytic Hydrogen Evolution on Metal Halide Perovskites
Authors: Xu Ting , Xie Yuxin , Qi Shengliang , Zhang Hefeng , Ma Weiguang , Wang Junhui , Gao Yuying , Wang Lianzhou , Zong Xu 
Published: July 2024

AbstractMetal halide perovskites (MHPs) have emerged as attractive candidates for producing green hydrogen via photocatalytic pathway. However, the presence of abundant defects and absence of efficient hydrogen evolution reaction (HER) active sites on MHPs seriously limit the solar‐to‐chemical (STC) conversion efficiency. Herein, to address this issue, we present a bi‐functionalization strategy through decorating MHPs with a molecular molybdenum‐sulfur‐containing co‐catalyst precursor. By virtue of the strong chemical interaction between lead and sulfur and the good dispersion of the molecular co‐catalyst precursor in the deposition solution, a uniform and intimate decoration of the MHPs surface with lead sulfide (PbS) and amorphous molybdenum sulfide (MoSx) co‐catalysts is obtained simultaneously. We show that the PbS co‐catalyst can effectively passivate the Pb‐related defects on the MHPs surface, thus retarding the charge recombination and promoting the charge transfer efficiency significantly. The amorphous MoSx co‐catalyst further promotes the extraction of photogenerated electrons from MHPs and facilitates the HER catalysis. Consequently, drastically enhanced photocatalytic HER activities are obtained on representative MHPs through the synergistic functionalization of PbS and MoSx co‐catalysts. A solar‐to‐chemical (STC) conversion efficiency of ca. 4.63 % is achieved on the bi‐functionalized FAPbBr3‐xIx (FA=CH(NH2)2), which is among the highest values reported for MHPs.
Photo‐Assisted Chemical Self‐Rechargeable Zinc Ion Batteries with High Charging and Discharging Efficiency
Authors: Du Xing‐Yuan , Song Li‐Na , Liang Shuang , Wang Yi‐Feng , Wang Yue , Wang Huan‐Feng , Xu Ji‐Jing 
Published: July 2024

AbstractChemical self‐recharging zinc ion batteries (ZIBs), which are capable of auto‐recharging in ambient air, are promising in self‐powered battery systems. Nevertheless, the exclusive reliance on chemical energy from oxygen for ZIBs charging often would bring some obstacles in charging efficiency. Herein, we develop photo‐assisted chemical self‐recharging aqueous ZIBs with a heterojunction of MoS2/SnO2 cathode, which are favorable to enhancing both the charging and discharging efficiency as well as the chemical self‐charging capabilities under illumination. The photo‐assisted process promotes the electron transfer from MoS2/SnO2 to oxygen, accelerating the occurrence of the oxidation reaction during chemical self‐charging. Furthermore, the electrons within the MoS2/SnO2 cathode exhibit a low transfer impedance under illumination, which is beneficial to reducing the migration barrier of Zn2+ within the cathode and thereby facilitating the uniform inserting of Zn2+ into MoS2/SnO2 cathode during discharging. This photo‐assisted chemical self‐recharging mechanism enables ZIBs to attain a maximum self‐charging potential of 0.95 V within 3 hours, a considerable self‐charging capacity of 202.5 mAh g−1 and excellent cycling performance in a self‐charging mode. This work not only provides a route for optimizing chemical self‐charging energy storage, but also broadens the potential application of aqueous ZIBs.
Nonalternant B,N‐Embedded Helical Nanographenes Containing Azepines: Programmable Synthesis, Responsive Chiroptical Properties and Spontaneous Resolution into a Single‐Handed Helix
Authors: Zhuang Weiwen , Hung Faan‐Fung , Che Chi‐Ming , Liu Junzhi 
Published: July 2024

AbstractHeteroatom‐embedded helical nanographenes (NGs) constitute an important and appealing class of intrinsically chiral materials. In this work, a series of B,N‐embedded helical NGs (BN‐HNGs) bearing azepines was synthesized via stepwise regioselective cyclodehydrogenation. First, the phenyl‐ or nitrogen‐bridged dimers were efficiently clipped into highly congested model compounds 1 and 2. Later, the controllable Scholl reactions of the tetraphenyl‐tethered precursor generated 1, 7 or 8 new C−C bonds, thereby establishing a robust method for the preparation of nonalternant BN‐HNGs with up to 31 fused rings. The helical bilayer nature was unambiguously verified by X‐ray diffraction analysis. The helical chirality was transferred to the stereogenic boron centers upon fluoride coordination, with a concave‐concave structure to comply with the bilayer skeleton. Notably, the largest nonalternant BN‐HNG (6) spontaneously resolved into a homochiral 41 helix structure as a molecular spiral staircase during crystallization via conglomerate formation at the single‐crystal scale. The large twisted C2‐symmetric π‐surface and the dynamic chiral skeleton induced by curved azepines might have synergistic effects on self‐recognition of enantiomers of 6 to achieve the intriguing spontaneous resolution behavior. The chiroptical properties of the enantiomer of 6 were further investigated, revealing that 6 had a strong chiroptical response in the visible range (400–700 nm).
Reversible electronic modulation of polydiacetylenes for sensing in dynamic conditions
Authors: Beliktay Gizem , Ozer Aybuke B. , Cingil Hande E. , Tan Eric M. M. 
Published: July 2024

AbstractPolydiacetylenes (PDAs) are renowned for their exceptional optical properties intricately linked to the polymer conformation, yet they exhibit poor conductivity in their undoped state. Despite this drawback, PDAs have garnered significant interest as sensing materials owing to their ability to undergo colorimetric shifts from blue to red in response to external stimuli. However, the irreversible nature of this transition has limited their utility in dynamic environments. In this study, we augment the sensing capabilities of PDA films beyond their irreversible optical response by inducing a reversible electronic response through conductivity modulation. We investigated polyamine‐substituted PDAs with enriched hydrogen‐bonding interaction sites for the concurrent changes in colorimetry and conductivity upon acetic acid (AA) vapor exposure. Coated on a flexible interdigitated electrode (IDE), we monitor the conductivity change throughout the blue‐to‐red phase transition. Remarkably, AA molecules act as dopants, significantly amplifying the system's conductivity. Although the PDA coating retains its red phase at postdopant removal, the electronic response reverts to its initial state, demonstrating reversibility. This reversible electronic response offers invaluable real‐time insights into the specific triggers within dynamic environments, underscores the adaptability of responsive conjugated polymers, and highlights a promising avenue for their utilization in various sensing and monitoring applications.
Sisal Fiber Reinforced and Cenosphere Hybridized Polypropylene‐SEBS Composite: An Insight into Crystallographic, Dynamic Mechanical and Rheological Behavior
Authors: Maurya Atul Kumar , Kumar Sachin , Chaudhari Arjun S. , Manik Gaurav 
Published: July 2024

AbstractThe current study attempts to explore the crystallographic, rheological and, dynamic mechanical properties of the submicron‐treated cenosphere (t‐ CSF) particles and sisal fiber (SF) reinforced Styrene‐(Ethylene‐Butylene)‐Styrene (SEBS) toughened PP hybrid composites. Moreover, the composites reinforced with 25 wt.% of SF and 5 wt.% of CSF (Treated 6 wt.% cetrimonium bromide (CTAB)) demonstrated the most significant storage modulus (E′), loss modulus (E”), and lowest damping (tan δ) factor throughout the temperature range. Likewise, X‐ray diffraction techniques were used to assess the samples’ crystallographic properties. The composites reported an enhanced β phase (responsible for high impact strength and reduced α phase of the base matrix compared to pristine PP. Likewise, all the composites’ rheological properties showed an improved complex viscosity (η*) compared to the BM but lower than that of the pristine PP. Overall processing parameters of the BM and composites were improved due to the decrement in the η* of all the composites. The rheological properties confirmed the easy processing of the fabricated composites due to the improved flowability. The storage (G′) and loss (G”) modulus of all the composites were desirably higher than that of the BM.
Digitales Datenmanagement für die Instandhaltung von Offshore‐Windparks
Authors: Eichner Lukas , Gerards‐Wünsche Paul , Happel Karina , Weise Sigurd , Haake Gerrit , Sieber Lars , Flederer Holger , Schneider Ronald , Herrmann Ralf , Hille Falk , Baeßler Matthias , Huhn Holger , Küchler Andreas 
Published: July 2024

AbstractIm Forschungsprojekt DiMoWind‐Inspect wurde untersucht, welche Grundvoraussetzungen geschaffen werden müssen, um digitale Methoden für die Instandhaltung von Offshore‐Windenergieanlagen einsetzen zu können. Daten aus allen Lebensphasen der Anlagen werden derzeit nur selten effizient dafür genutzt, um die sinnvollsten Instandhaltungsmaßnahmen am richtigen Ort, zum richtigen Zeitpunkt und mit den geringsten Kosten durchzuführen. Eine im Vorhaben entwickelte einheitliche Strukturierung der bisher häufig unstrukturierten Bau‐ und Instandhaltungsdaten ermöglicht ihre übergreifende, anwenderspezifische Verfügbarkeit. Hierfür werden Prinzipien des Referenzkennzeichnungssystems RDS‐PP adaptiert. Es wird aufgezeigt, wie neben Bauteilen auch zusätzliche Informationen wie Instandhaltungsmaßnahmen oder Mängel strukturiert werden können. Dem Ansatz des Building Information Modeling folgend werden die Bauwerkskomponenten direkt mit den Informationen aus Inspektionen und weiteren Instandhaltungsmaßnahmen verknüpft. So können Informationen aus dem Betrieb über den Zustand der Struktur verarbeitet und für die maßgebenden Berechnungen und Nachweise zur Verfügung gestellt werden. Als Anwendungsfall wird ein zweistufiges Konzept vorgestellt, das zur Bewertung der Ermüdungslebensdauer eines korrosionsgeschädigten Konstruktionsdetails der Gründungsstruktur einer Offshore‐Windenergieanlage mit Informationen aus der Instandhaltung eingesetzt wird.
Thermite frass biomass and surface modified biowaste coir fiber reinforced biocomposites—Conversion of waste to useful products
Authors: Sajin Justin Abraham , Sreenivasan Vaithilingam Shanmugavelayutham , Bright Brailson Mansingh , Saravanan Murugan Sundaram Senthil , Tharayil Trijo , Anish Raveendra Kurup , Natarajan Manikandan , Bharathiraja Govindarajan , Binoj Joseph Selvi 
Published: July 2024

AbstractPolymer composites are known for its light weight and specific mechanical characteristics. This study examines sodium hydroxide (NaOH)‐treated coir fiber, an agro‐leftover, stuffed in a polyester matrix with termite frass powder, a bio‐leftover for possible use in light‐weight structural applications. Composite samples were made using compression molding and NaOH‐treated coir fiber reinforced hybrid polymer composite (TCRHPC) with 40 wt% treated coir fiber and 1, 2, 3, and 4 wt% termite frass powder. TCRHPC samples mechanical, water captivation, tribological, and thermal properties were affected by termite frass powder wt%. The TCRHPC sample with 3 wt% termite frass powder has excellent mechanical properties, which improved by tensile (41.6%), flexural (28.57%), impact (43.7%), and hardness (18.84%) properties. With perfect water captivation and low weight increases in normal water (0.017 g), seawater (0.015 g), and NaOH solution (0.010 g), the identical composite sample with thermal stability up to 238°C also reduced wear mass by 5.27%. Conversely, filler agglomeration and heterogeneous dispersion in composite sample impair thermo‐mechanical characteristics of TCRHPC containing 4 wt% termite frass powder. The bonding among polyester, treated coir fiber, and termite frass powder in composites were appraised with the aid of fractographic images of TCRHPC samples. The results show that TCRHPC material suits well for support structures requiring lesser weight.
Impacts of green innovation on small and medium enterprises' performance: The role of sustainability readiness and firm size
Authors: Schrank Johannes , Kijkasiwat Ploypailin 
Published: July 2024

AbstractThis study investigates the influence of green innovation and technology in both products and processes on the performance of small and medium‐sized enterprises (SMEs) in Thailand. Additionally, it explores the impact of firm size and sustainability readiness on SME performance and examines the moderating and mediating effects of these factors on the relationship between innovation and firm performance. Structural equation modeling (SEM) was employed as the methodological approach, utilizing a sample of 421 SMEs in Thailand. The findings reveal that green innovation and sustainability readiness significantly contribute to SME performance. Sustainability readiness is identified as a mediator, underscoring its significant role in mediating the relationship between green innovation and firm performance. Furthermore, firm size is confirmed as a moderator, indicating that the influence of green innovation on firm performance is contingent upon the firm's size. These findings have significant implications for SMEs, providing valuable insights into strategic investments in sustainability readiness and green innovation as avenues for enhancing performance and competitiveness.
Comparison of treatment outcome between first‐line combination immunotherapy (anti‐PD‐L1 or anti‐PD1) with or without chemotherapy and chemotherapy alone in advanced non‐small cell lung cancer patients in tertiary care hospital
Authors: Naratornsirakul Danainut , Chewaskulyong Busyamas , Kongkarnka Sarawut , Oranratnachai Songporn 
Published: July 2024

AbstractBackgroundDespite promising outcomes of first‐line immunotherapy with or without chemotherapy in advanced non‐small cell lung cancer (NSCLC), limited accessibility due to reimbursement was remain the problem in low to middle income countries. This study aimed to evaluate real‐world effectiveness of immunotherapy in patients with advanced NSCLC in Northern Thailand.MethodA retrospective, single‐centered cohort, was conducted. Patients with advanced NSCLC who underwent PD‐L1 testing (excluding EGFR and ALK mutations) and were treated with immunotherapy or without chemotherapy or chemotherapy alone were included. The primary end point was progression‐free survival (PFS). The secondary endpoints were overall survival (OS), objective response rate (ORR), and adverse events.ResultsA total of 123 patients, of which 21 patients received immunotherapy‐based regimen and 102 patients received chemotherapy alone. The median PFS was 11.9 months in immunotherapy‐based group compared to 5.93 months in the chemotherapy group, with a. hazard ratio (HR) of 0.4 (95% confidence interval [CI], 0.23 to 0.68; p = 0.001). Similarly, the median OS was 26.68 months in the immunotherapy‐based group and 11.21 months in the chemotherapy group, with HR of 0.42 (95% CI 0.22–0.8; p = 0.009). ORRs were significantly higher in the immunotherapy‐based group, with 65% of patients showing a response compared to 32% in the chemotherapy group (p = 0.006).ConclusionThe result of this real‐world study in patients with advanced stage NSCLC indicate that first‐line immunotherapy‐based regimen was associated with significantly greater PFS, OS, and ORR with a safety profile consistent with pivotal studies.
Cuproptosis‐related gene DLAT is a biomarker of the prognosis and immune microenvironment of gastric cancer and affects the invasion and migration of cells
Authors: Peng Yanyu , Shi Ruimeng , Yang Siwen , Zhu Jiayi 
Published: July 2024

AbstractObjectiveCuproptosis is a novel cell death dependent on mitochondrial respiration and regulated by copper. This study aimed to investigate the cuproptosis‐related gene DLAT potential value in gastric cancer (GC).MethodsBioinformatics was used to analyze DLAT expression. DLAT expression in GC cell lines was detected using qRT‐PCR. Cell proliferation ability was assessed using CCK8 and cell cycle assay. Cell migration and invasion were assessed using wound healing and transwell assay. A prognostic assessment was performed through survival and Cox regression analysis. DLAT protein expression was analyzed through HPA immunohistochemistry. Biological functions and processes were analyzed through GO and KEGG enrichment analysis and PPI. Correlation with immune cell infiltration and immune checkpoint genes was analyzed for DLAT.ResultsDLAT expression was upregulated in GC tissues and cells and correlated with shorter survival for patients. Age, gender, histological typing, lymph node metastasis, and distant metastasis were identified as independent prognostic factors affecting OS in GC. DLAT protein was upregulated in GC. The biological functions and pathways enriched in DLAT were mainly linked to mitochondrial respiration and the TCA cycle. The expression of DLAT was found to be positively correlated with the infiltration of Th and Th2 immune cells and only positively correlated with the expression of the BTN2A1 immune checkpoint gene.ConclusionDLAT has the potential to serve as a prognostic assessment factor in GC. The expression of DLAT was correlated with immune infiltration and tumor immune escape, providing a new target for immunotherapy of GC.
Comprehensive analysis of serum cytokines in patients with multiple myeloma before and after lenalidomide and dexamethasone
Authors: Tachita Takuto , Ri Masaki , Aoki Sho , Asano Arisa , Kanamori Takashi , Totani Haruhito , Kinoshita Shiori , Asao Yu , Narita Tomoko , Masaki Ayako , Ito Asahi , Kusumoto Shigeru , Komatsu Hirokazu , Iida Shinsuke 
Published: July 2024

AbstractMultiple myeloma (MM) is an incurable B‐cell malignancy often accompanied by profound immunodeficiency. Lenalidomide (Len) is an immunomodulatory drug that exerts promising therapeutic effects on MM through the immune system. However, predictive markers related to the effects of Len treatment are not fully understood. This study aimed to identify candidate biomarkers for predicting the clinical efficacy of Len and dexamethasone (Ld) therapy through a comprehensive analysis of serum cytokines. The levels of 48 cytokines in the serum of patients with MM just before Ld therapy (n = 77), at the time of best response (n = 56), and at disease progression (n = 49) were measured and evaluated. Patients with high IL‐18 and M‐CSF levels showed significantly shorter progression‐free survival and overall survival (OS). In contrast, patients with high PDGF‐BB levels had longer survival. Moreover, low levels of G‐CSF, IL‐7, IL‐8, and SDF‐1α were associated with shorter OS after Ld therapy. During Ld therapy, pro‐inflammatory cytokines such as IL‐2Rα, IL‐18, and TNF‐α were decreased, while IFN‐γ was increased. IL‐4 and IL‐6 levels increased during disease progression. In conclusion, this study provides a better understanding of the association between cytokines and the efficacy of Ld therapy as well as the unique changes in cytokines related to inflammatory and immune responses during Ld therapy.
Real‐world evidence of brigatinib as second‐line treatment after crizotinib for ALK+ non‐small cell lung cancer using South Korean claims data (K‐AREAL)
Authors: Lee Jeong Eun , Nam Jin Hyun , Kwon Sun Hong , Kim Bo Kyung , Ha Seung Min 
Published: July 2024

AbstractPurposeThere is a lack of real‐world data in Asian populations for brigatinib, a next‐generation anaplastic lymphoma kinase (ALK) inhibitor for patients with non‐small cell lung cancer (NSCLC). This study analysed real‐world outcomes and dosing patterns for brigatinib in patients with crizotinib‐refractory ALK+ NSCLC in South Korea.MethodsThis retrospective, non‐interventional, cohort study used South Korean Health Insurance and Review Assessment claims data for adults with ALK+ NSCLC who initiated brigatinib between 19 April 2019 and 31 March 2021 after receiving prior crizotinib. Patients' characteristics, time to discontinuation (TTD), time to dose reduction, overall survival (OS) and treatment adherence were assessed.ResultsThe study included 174 patients (56.9% male; 27.0% with a history of brain metastases). Median duration of prior crizotinib was 17 (range 0.3–48) months. Median follow‐up after brigatinib initiation was 18 (range 0–34) months. Overall, 88.5% of patients received full‐dose brigatinib (180 mg/day) and 93.1% of patients were adherent (proportion of days covered ≥0.8). The median TTD was 24.9 months (95% CI 15.2–not reached). The probability of continuing treatment was 63.2% at 1 year and 51.5% at 2 years. The probability of continuing at full or peak dose was 79.7% at 1 year and 75.6% at 2 years. Median OS was not reached. The 2‐year OS rate was 68.7%.ConclusionsIn this first nationwide retrospective study using national insurance claim data, brigatinib demonstrated real‐world clinical benefit as second‐line treatment after prior crizotinib in ALK+ NSCLC patients in South Korea.
Effects of housing stability and contemporary mortgage lending bias on breast cancer stage at diagnosis among older women in the United States
Authors: Rademacher Nicole , Zhou Yuhong , McGinley Emily L. , Laud Purushottam W. , Yen Tina W. F. , Ponce Sara Beltrán , Nattinger Ann B. , Beyer Kirsten M. M. 
Published: July 2024

AbstractBackgroundInterventions aimed at upstream factors contributing to late‐stage diagnoses could reduce disparities and improve breast cancer outcomes. This study examines the association between measures of housing stability and contemporary mortgage lending bias on breast cancer stage at diagnosis among older women in the United States.MethodsWe studied 67,588 women aged 66–90 from the SEER‐Medicare linked database (2010–2015). The primary outcome was breast cancer stage at diagnosis. Multinomial regression models adjusted for individual and neighborhood socio‐economic factors were performed using a three‐category outcome (stage 0, early stage, and late stage). Key census tract‐level independent variables were residence in the same house as the previous year, owner‐occupied homes, and an index of contemporary mortgage lending bias.ResultsIn models adjusted for individual factors, higher levels of mortgage lending bias were associated with later stage diagnosis (RR = 1.10, 95% CI 1.02–1.20; RR = 1.31, 95% CI 1.16–1.49; RR = 1.41, 95% CI 1.24–1.60 for least to high, respectively). In models adjusted for individual and neighborhood socio‐economic factors, moderate and high levels of mortgage lending bias were associated with later stage diagnosis (RR = 1.16, 95% CI 1.02–1.33 for moderate and RR = 1.18, 95% CI 1.02–1.37 for high). Owner occupancy and tenure were not associated with later stage diagnosis in adjusted models.ConclusionsContemporary mortgage lending bias demonstrated a significant gradient relationship with later stage at diagnosis of breast cancer. Policy interventions aimed at reducing place‐based mortgage disinvestment and its impacts on local resources and opportunities should be considered as part of an overall strategy to decrease late‐stage breast cancer diagnosis and improve prognosis.