bluuebunny/crossref_metadata_2025_split huggingface dataset:
Minireview: Directed Differentiation and Encapsulation of Islet β-Cells—Recent Advances and Future Considerations
Authors: Tse Hubert M. , Kozlovskaya Veronika , Kharlampieva Eugenia , Hunter Chad S. 
Published: September 2015

AbstractDiabetes mellitus has rapidly become a 21st century epidemic with the promise to create vast economic and health burdens, if left unchecked. The 2 major forms of diabetes arise from unique causes, with outcomes being an absolute (type 1) or relative (type 2) loss of functional pancreatic islet β-cell mass. Currently, patients rely on exogenous insulin and/or other pharmacologies that restore glucose homeostasis. Although these therapies have prolonged countless lives over the decades, the striking increases in both type 1 and type 2 diabetic diagnoses worldwide suggest a need for improved treatments. To this end, islet biologists are developing cell-based therapies by which a patient's lost insulin-producing β-cell mass is replenished. Pancreatic or islet transplantation from cadaveric donors into diabetic patients has been successful, yet the functional islet demand far surpasses supply. Thus, the field has been striving toward transplantation of renewable in vitro-derived β-cells that can restore euglycemia. Challenges have been numerous, but progress over the past decade has generated much excitement. In this review we will summarize recent findings that have placed us closer than ever to β-cell replacement therapies. With the promise of cell-based diabetes therapies on the horizon, we will also provide an overview of cellular encapsulation technologies that will deliver critical protection of newly implanted cells.
Heregulin Co-opts PR Transcriptional Action Via Stat3 Role As a Coregulator to Drive Cancer Growth
Authors: Proietti Cecilia J. , Izzo Franco , Díaz Flaqué María Celeste , Cordo Russo Rosalía , Venturutti Leandro , Mercogliano María Florencia , De Martino Mara , Pineda Viviana , Muñoz Sergio , Guzmán Pablo , Roa Juan C. , Schillaci Roxana , Elizalde Patricia V. 
Published: September 2015

Abstract
Accumulated findings have demonstrated the presence of bidirectional interactions between progesterone receptor (PR) and the ErbB family of receptor tyrosine kinases signaling pathways in breast cancer. We previously revealed signal transducer and activator of transcription 3 (Stat3) as a nodal convergence point between said signaling pathways proving that Stat3 is activated by one of the ErbBs' ligands, heregulin (HRG)β1 via ErbB2 and through the co-option of PR as a signaling molecule. Here, we found that HRGβ1 induced Stat3 recruitment to the promoters of the progestin-regulated cell cycle modulators Bcl-XL and p21CIP1 and also stimulated Stat3 binding to the mouse mammary tumor virus promoter, which carries consensus progesterone response elements. Interestingly, HRGβ1-activated Stat3 displayed differential functions on PR activity depending on the promoter bound. Indeed, Stat3 was required for PR binding in bcl-X, p21CIP1, and c-myc promoters while exerting a PR coactivator function on the mouse mammary tumor virus promoter. Stat3 also proved to be necessary for HRGβ1-induced in vivo tumor growth. Our results endow Stat3 a novel function as a coregulator of HRGβ1-activated PR to promote breast cancer growth. These findings underscore the importance of understanding the complex interactions between PR and other regulatory factors, such as Stat3, that contribute to determine the context-dependent transcriptional actions of PR.
Synthesis of Silver-coated Copper Particles with Thermal Oxidation Stability for a Solar Cell Conductive Paste
Authors: Shin Jongmin , Kim Hyunju , Song Kwang Ho , Choe Jaehoon 
Published: September 2015

Abstract
Spherical thiocyanate-coated Cu@Ag particles were synthesized by a galvanic replacement reaction. These particles were used to fabricate a conductive paste, which was printed on silicon wafers to manufacture inexpensive silicon-wafer-based solar cells. Cells with the thiocyanate-coated Cu@Ag particles showed comparatively favorable solar cell efficiencies because of improved thermal oxidation resistance, resulting from the deposited β-CuSCN layers on the Cu@Ag particles.
An Fe-based Model for Metabolism Linking between O2-reduction and H2O-oxidation
Authors: Yatabe Takeshi , Kikkawa Mitsuhiro , Matsumoto Takahiro , Urabe Keishi , Robertson Andrew , Nakai Hidetaka , Ogo Seiji 
Published: September 2015

Abstract
Here, we report the first Fe-based model for metabolism linking between the dioxygen reduction of respiration and the water oxidation of photosynthesis. The reaction mechanism was investigated by X-ray analysis, UV–vis spectroscopy, and mass spectrometry.
Pyxidiculacompressa: Diatom or dinoflagellate?
Authors: Cowan Roberta A. , Huisman John M. 
Published: September 2015

AbstractThe taxonomic position of Pyxidicula compressa, currently the nomenclatural basionym of two unrelated taxa (a diatom and a dinoflagellate), is clarified. Evidence is presented that the protologue of the species clearly represents a diatom, which is then correctly known as Tryblionella compressa. In the absence of original specimens, the species is lectotypified with illustrations from the protologue. It is proposed that the name Prorocentrum bidens be adopted for the dinoflagellate presently known as Prorocentrum compressum.
Towards resolving phylogenetic relationships in the Ficinia clade and description of the new genus Afroscirpoides (Cyperaceae: Cypereae)
Authors: García-Madrid Ana S. , Muasya A. Muthama , Álvarez Inés , Cantó Paloma , Molina José Antonio 
Published: September 2015

AbstractCyperaceae is the third‐largest family of monocotyledons and one of the 10 largest families of angiosperms. The family includes two subfamilies and several tribes, one of which, Cypereae, is the aim of the present study. Recent studies recognize the Ficinia clade, composed of six genera (Dracoscirpoides, Erioscirpus, Ficinia, Hellmuthia, Isolepis, Scirpoides), as more closely related to Cyperus (Cypereae) than to Scirpus (Scirpeae), where it was traditionally placed. In this study, phylogenetic analyses of the Ficinia clade have been carried out, based on sequences of two nrDNA loci (ITS, ETS1f) and three plastid loci (trnL intron, rps16, trnH‐psbA) and with special attention to the smaller genera of the clade (i.e., Dracoscirpoides, Erioscirpus, Hellmuthia, Scirpoides). Results revealed a strong geographic pattern within Scirpoides, in which two groups are identified, one including the southern African and the other representing the northern hemisphere species. Dracoscirpoides and Erioscirpus are monophyletic genera while Hellmuthia formed a clade with Ficinia and Isolepis. One species of Scirpoides (S. dioeca) was outside the clade of Scirpoides s.str. in the analyses, and is here transferred to a new monospecific genus endemic to southern Africa: Afroscirpoides.
Lexicographic Work with Foreign Linguistics Students Who Study Russian As a Foreign Language. Advanced Level
Authors: Антропова  , Antropova M. 
Published: September 2015

The article represents the author’s experience in creating a PR-glossary in
the course of lessons of the Russian language with foreign students who
study in Russian higher education institutions at the programme “Advertising
and Public Relations”. The author considers work on creating a glossary
not only as a traditional method of enlarging a student’s vocabulary but
also as an innovative method of teaching students to understand and use
vocabulary of the publicistic style on the basis of such modern sources as
online magazines, online newspapers, websites, the corpus of the Russian
language and online dictionaries, thus developing students’ lexicographic
skills.
Verbal Communication in Mass Media
Authors: Ржанова  , Rzhanova S. 
Published: September 2015

The article analyzes the communication process of modern mass media.
Journalism, holding true to its methods of undestanding reality, turns to the
postmodern manner of writing. Dialogueness of mass communication is
built on different levels. Speech reflects contradictory processes, which occur
in our life and are accompanied by changing moral values and spiritual
guidelines. Language occurrences in different kinds of mass communication
break up the foundations of Russian culture. A new information environment
should be created in agreement with the historical traditions and
linguistic culture of the society.
Tendência temporal de indicadores da prática de atividade física e comportamento sedentário nas capitais da Região Norte do Brasil: 2006-2013
Authors: Mielke Grégore , Costa Danylo , Stopa Sheila , Oliveira-Campos Maryane , Pureza Demilto , Silva Marta 
Published: September 2015

<p class="MsoNormal" style="margin-bottom: .0001pt; text-align: justify; text-justify: inter-ideograph; line-height: 200%;"><span style="font-size: 12.0pt; line-height: 200%; font-family: ";Times New Roman";,serif;">O objetivo deste estudo foi descrever as mudanças na prática de atividade física nas capitais da região Norte entre 2006 e 2013. Foram analisados os dados de adultos (18+ anos) que fizeram parte do Sistema de Vigilância de Fatores de Risco e Proteção para Doenças Crônicas por Inquérito Telefônico (VIGITEL), das capitais de estados da região Norte do Brasil (Acre, Amazonas, Amapá, Pará, Rondônia, Roraima, Tocantins) no período de 2006 a 2013. Foram analisadas as tendências de atividade física no tempo livre, deslocamento a pé ou de bicicleta para ir/voltar do trabalho/escola, prevalência de inatividade física considerando todos os domínios (lazer, deslocamento, trabalho e tarefas domésticas), além da proporção de adultos que relataram três ou mais horas assistindo televisão por dia. Para os indicadores de atividade física no tempo livre, prevalência de adultos que assistiram televisão por três ou mais horas/dia e prevalência de inatividade física não foram observadas mudanças no período analisado. Houve uma redução na proporção de adultos que relataram se deslocar a pé ou de bicicleta para o trabalho/escola de 19,1% em 2009 para 11,8% em 2013 (p=0,004). A região Norte apresenta uma tendência de diminuição no deslocamento ativo semelhante à tendência nacional, enquanto que a prática de atividade física no lazer permaneceu estável. Monitorar os indicadores de atividade física no contexto regional pode auxiliar gestores no direcionamento de políticas de promoção da atividade física. </span></p>
Tendência temporal de indicadores da prática de atividade física e comportamento sedentário nas capitais da Região Nordeste do Brasil: 2006-2013
Authors: Tassitano Rafael , Mielke Grégore , Carvalho Wellington , Oliveira Max , Malta Deborah 
Published: September 2015

<p class="Padro" style="margin-bottom: 0.0001pt; text-align: justify;"><span style="font-size: 12.0pt; font-family: ";Times New Roman";,serif; mso-fareast-font-family: ";Times New Roman";; color: windowtext; mso-bidi-font-weight: bold;" lang="PT">O objetivo foi analisar tendências temporais de indicadores da prática de atividade física e comportamento sedentário nas capitaisda região Nordeste entre os anos de 2006 e 2013. Foram analisados dados de 141.309 adultos (18+ anos), das nove capitais, da região Nordeste do Brasil, participantes do Sistema de Vigilância de Fatores de Risco e Proteção para Doenças Crônicas por Inquérito Telefônico. Os indicadores foram: ativo no tempo livre (150 minutos/semana de intensidade leve ou moderada ou 75 minutos/semana de intensidade vigorosa); ativo no deslocamento (≥30 minutos/dia caminhando ou pedalando para ir/ voltar do trabalho ou escola); fisicamente inativo (não realizar esforços físicos intensos e não praticar qualquer atividade no tempo livre nos últimos três meses) e comportamento sedentário (assistir três ou mais horas de televisão por dia). Os dados foram analisados no STATA e análises de tendência temporal foram feitas estratificadas por sexo, faixa etária, escolaridade e capitais. A proporção de adultos fisicamente ativos no tempo livre aumentou de 29,4% em 2009 para 34,5% em 2013, enquanto que houve uma redução significativa entre os que se deslocam ativamente (16,6% em 2009 vs 11,2% em 2013). O tempo de televisão e a inatividade física permaneceram estáveis ao longo dos anos. Ao longo dos anos foi observado mudanças sociais e econômicas na região. A implementação da Política Nacional de Promoção da Saúde </span><span style="font-size: 12.0pt; font-family: ";Times New Roman";,serif; color: windowtext;" lang="PT">universalizou o acesso à prática de atividade física, contudo ações integradas devem ser implementadas para atingir os diferentes subgrupos e domínios. </span></p>
Assiduidade a programas de atividade física oferecidas por Unidades Básicas de Saúde: o discurso de participantes muito e pouco assíduos
Authors: Lovato Natália , Loch Mathias , González Alberto , Lopes Maria 
Published: September 2015

<p class="MsoNormal" style="margin-bottom: .0001pt; text-align: justify; line-height: 200%;"><span style="font-size: 12.0pt; line-height: 200%; font-family: ">O objetivo da pesquisa foi avaliar o discurso sobre alguns elementos da participação em grupos de prática de atividade física (AF) em usuários de programas oferecidos por duas Unidades Básicas de Saúde na cidade de Londrina/PR. Foi realizado estudo transversal, com abordagem qualitativa. Os dados foram coletados através de entrevista semi-estruturada. Os 105 usuários dos programas de AF foram divididos em cinco quintis, de acordo com a assiduidade. Foram entrevistados os sujeitos do quintil com maior assiduidade (n=21) e do com menor assiduidade (n=21). Na análise das entrevistas, utilizou-se a análise</span><span style="font-size: 12.0pt; line-height: 200%; font-family: "> categorial de conteúdos preconizada por Bardin. </span><span style="font-size: 12.0pt; line-height: 200%; font-family: ">Em linhas gerais as falas revelaram que os sujeitos gostam de praticar AF, dentro ou fora do grupo, que os sentimentos vivenciados durantes as atividades eram positivos, que a motivação de familiares foi considerada importante fator de assiduidade ao programa, que muitos usuários observam melhorias na sua saúde com a participação no programa e que, entre os usuários com menor assiduidade, questões interpessoais, especialmente compromissos familiares, foram importantes para o não comparecimento em algumas atividades. Recomenda-se que a questão da aderência aos programas de AF seja levada em consideração no planejamento e replanejamento das ações, inclusive refletindo sobre as características dos programas ofertados (horário, local, tipo de atividades, etc). </span></p>
Bringing practice closer to research – seeking integrity, sincerity and authenticity
Authors: Schroeder Franziska 
Published: September 2015

Abstract
This article tackles the abundance of inconsistent terminologies that surround the discourse on practice and research. The text builds on recent debates on creative practice and education, sparked through the EU-funded project SHARE. I argue that a shift in contemporary continental philosophy in the 1970s, which nudged the body into a more central position, allowed for creative practice and with it ‘embodied knowing’ to slowly push open the doors of the academies. I will show that practice today is already well embedded in some UK institutions, and I put forward that rather than thinking of an apologetic Practice as …, Performance as …, we should refer more resolutely to what I here term ‘Practice Research’. I demystify notions of validation of creative practice by re-emphasizing the artistic qualities of ‘integrity, sincerity and authenticity’, borrowed from the 2013 BBC Reith lecturer and artist/potter Grayson Perry.
The politics and the poetics of knowledge in higher arts education
Authors: Cabeleira Helena 
Published: September 2015

Abstract
This article aims to contribute to the analysis and problematization of a discourse that took shape in international universities (over the last two decades) around terminologies, methodologies and conceptions of academic research and writing in the creative fields of art and design. This discourse has been particularly visible in the past decade, in consequence of the Bologna Process and the formation of a European Higher Arts Education Area. Framed by this discourse emerged the figure of the artist-researcher as writer conducing his or her doctoral studies, and inventing theoretical and empirical strategies through which art and design practices articulate with research-writing practices, and the conditions under which these practices are communicated and disseminated in the public sphere as knowledge (texts and images). A literature review and a European overview on how articulations between text-making and art-making are being theorized and materialized in publications, conferences and curricular programmes will be provided.
Teaching and learning for sustainability: An Icelandic practice-based research
Authors: Jónsdóttir Ásthildur 
Published: September 2015

Abstract
We live in critical times, where moving towards the goal of sustainability requires fundamental changes in human attitudes and activity. These challenges call for all of us to rethink our value framework and incorporate new approaches to what we consider a good life. Educators need to strive to create change and work towards a sustainable future through education for sustainability (EFS). This article reports on a project in which the author worked with a group of pre-service art teachers in the Iceland Academy of the arts (IAA) to explore how they can use an artistic approach to learn about EFS, identifying and discovering ethical challenges in contemporary life. This is part of a larger study, which looks at the potential of art in EFS. Using a participatory research method these students analysed which concept they wanted to focus on once they became practising art teachers. The findings indicate connections between action and reflection through an artistic approach.
Extremism or terrorism: Communicating Islamophobia on YouTube in the Norwegian attacks
Authors: Yusha’u Muhammad Jameel 
Published: September 2015

Abstract
This article studies the social media reporting of the Norwegian attacks by Anders Breivik with specific focus on the user commentary of YouTube versions of the breaking story in four media organizations, namely CNN, BBC, NBC and PJTV. Within the context of Islamophobia, the article uses critical discourse analysis (CDA) to understand the thread of the reporting and user comments on the Norwegian attacks. It is important to combine the two theoretical approaches because Islamophobia, as discussed by Allen (2010), is rising in Europe, and the swift reaction of the media in attributing terror attacks to Muslims without scrutiny shows how crucial it is to situate the study within the Islamophobia paradigm, while CDA will help us to understand the Islamophobic themes that emerged in the reporting of the story, and how the user-generated comments can contribute to our understanding of the rise of Islamophobia in the West. The study found three key themes that dominated discussions among the users on YouTube: intolerance/violence/immigration associated with Muslims in Europe, conspiracy theories and counter or alternative views from the opinions expressed by some users. This article concludes by agreeing with the position of Freedman and Thussu (2012) that there is a need to address the way stories about Muslims are reported in the West, otherwise there could be serious consequences for society, including foreign policy mistakes that can be avoided.
Transformative pan-Arab TV: National and cultural expression on reality TV programmes
Authors: Miladi Noureddine 
Published: September 2015

Abstract
This article analyses season two of the Arab reality TV programme titled Arab Idol, a TV series broadcast on the Saudi satellite channel MBC between 8 March and 22 June 2013. Through analysing this case study of Arab Idol, this article explores the rapid success of this genre on pan-Arab TV and attempts to decipher its audience’s interaction both online and on TV. It also seeks to unpack issues relating to the way identity, culture and nationalism are represented and debated. These programmes have been critically analysed following Fowler’s (1991) and Fairclough’s (2003) seminal texts. Results of this study reveal that the development of such a genre of TV programming in the region has opened up a new era not only for unusual entertainment but also for audience participation and engagement. As much as it can be perceived as a space for virtual democratic practice and free debates on nationalism and identity, this programme can also be considered as a unifying sphere that consolidates not only the feeling of national belonging but also the pan-Arab collective sense of the Ummah (global community).
Publishing in transition – do we still need scientific journals?
Authors: Grossmann Alexander 
Published: September 2015

Abstract
For decades, scientific journals were the only way to communicate new research findings. Up until today, very little has changed in that respect. The overwhelming majority of all scientific journals still functions as they did in the times when there was no Internet, no social networks, or crowd-based knowledge platforms. Is this form of dissemination of research findings still suitable in the 21st century? The author says: no.
Some characteristics of the resultant air flow from motions induced by ventilation and heat source in a two-dimensional enclosure
Authors: Tran T. V. , Thuy N. T. 
Published: September 2015

Ventilated air flow in an enclosure is often unsteady (turbulent) at even very low Reynolds number (Re). Meantime natural convection in a box is stationary motion at large enough Rayleigh number (Ra). This paper deals with the interaction between two those flows in a two-dimensional room. The room has one inlet and one or two outlets. A heat source locates on the floor. The numerical simulation of the interaction is carried out at some values of Re and Ra for two cases of the inlet and outlet configuration. Some interesting characteristics of the resultant flow are discovered. The heat amount released by the source and removed from the room by different types of this flow is also provided.
Management and outcomes of significant non-culprit coronary artery lesions in STEMI: a retrospective cohort study
Authors: Weitemeyer Robert Erich Michael , Murphy Shane Peter , Gillen Ruth , Ahern Catriona , Abusalma Yousif , Yagoub Hatim A , Yan Bryan P , Ajani Andrew E , Hannigan Ailish , Kiernan Tom J 
Published: September 2015

<p>BACKGROUND<br /> In the setting of ST-elevation myocardial infarction (STEMI) and multi-vessel disease (MVD), guidelines recommend revascularization of the culprit lesion (CL) only, due to poor evidence supporting intervention in non-culprit lesions (non-CLs) during the same index procedure. Debate over management for significant non-CLs is of interest i.e. medical management vs. percutaneous revascularization. We describe a cohort of patients with STEMI and MVD and compare the occurrence of major adverse cardiac events (MACE) by therapeutic strategies for non-CLs with regard to follow-up outcomes.</p><p>METHODS<br /> 86 patients with STEMI and MVD were identified from a database of STEMI presentations to the University Hospital Limerick from Jan 2011 to April 2013. The occurrence of MACE was established by follow up with patients’ general practitioners.</p><p>RESULTS<br /> 48% of presentations had MVD. Predominant management for non-CLs was medical therapy alone comprising 58% (n=50) of patients, while 23% (n=20) of patients underwent PCI for non-CL, and 19% (n=16) had CABG.</p><p>Median follow up was 1.8 years (range 9–36 months). We found no significant difference in the occurrence of MACE between medical management of non-CLs and PCI of non-CLs (OR 1.10 95%CI 0.34, 3.56; p= 0.88). CABG however does show a trend to be superior to both PCI (OR 3.10 95%CI 0.54, 17.88; p= 0.21) and medical management (OR 2.83 95%CI 0.65, 12.27; P= 0.17) in non-CLs.</p><p>CONCLUSIONS<br /> CABG appears superior to both PCI or medical management in preventing MACE over time, and PCI is not superior to medical management alone.</p>