bluuebunny/crossref_metadata_2025_split huggingface dataset:
Quantum Dots Mediated Crystallization Enhancement in Two-Step Processed Perovskite Solar Cells
Authors: Liu Heng , Jin Geyu , Wang Jiantao , Zhang Weihai , Qing Long , Zhang Yao , Lu Qiongqiong , Yue Pengfei , Zhang Guoshang , Wei Jing , Li Hongbo , Wang Hsing-Lin 
Published: February 2025

Abstract
Hybrid organic–inorganic lead halide perovskites have emerged as a promising material for high-efficiency solar cells, yet challenges related to crystallization and defects limit their performance and stability. This study investigates the use of perovskite quantum dots (QDs) as crystallization seeds to enhance the quality of FAPbI3 perovskite films and improve the performance of perovskite solar cells (PSCs). We demonstrate that CsPbI3 and CsPbBr3 QDs effectively guide the crystallization process, leading to the formation of larger crystals with preferential orientations, particularly the (001) and (002) planes, which are associated with reduced defect densities. This seed-mediated growth strategy resulted in PSCs with power conversion efficiencies (PCEs) of 24.75% and 24.11%, respectively, compared to the baseline efficiency of 22.05% for control devices. Furthermore, devices incorporating QD-treated perovskite films exhibited remarkable stability, maintaining over 80% of their initial PCE after 1000 h of simulated sunlight exposure, a significant improvement over the control. Detailed optoelectronic characterization revealed reduced non-radiative recombination and enhanced charge transport in QD-treated devices. These findings highlight the potential of QDs as a powerful tool to improve perovskite crystallization, facet orientation, and overall device performance, offering a promising route to enhance both efficiency and stability in PSCs.
LONGEST CYCLES AND LONGEST CHORDLESS CYCLES IN
$2$
-CONNECTED GRAPHS
Authors: HU YANAN , LI CHENGLI , LIU FENG 
Published: February 2025

Abstract
Thomassen’s chord conjecture from 1976 states that every longest cycle in a

$3$

-connected graph has a chord. The circumference

$c(G)$

and induced circumference

$c'(G)$

of a graph G are the length of its longest cycles and the length of its longest chordless cycles, respectively. Harvey [‘A cycle of maximum order in a graph of high minimum degree has a chord’, Electron. J. Combin.24(4) (2017), Article no. 4.33, 8 pages] proposed the stronger conjecture: every

$2$

-connected graph G with minimum degree at least

$3$

has

$c(G)\geq c'(G)+2$

. This conjecture implies Thomassen’s chord conjecture. We observe that wheels are the unique Hamiltonian graphs for which the circumference and the induced circumference differ by exactly one. Thus, we need only consider non-Hamiltonian graphs for Harvey’s conjecture. We propose a conjecture involving wheels that is equivalent to Harvey’s conjecture on non-Hamiltonian graphs. A graph is

$\ell $

-holed if all its holes have length exactly

$\ell $

. We prove that Harvey’s conjecture and hence also Thomassen’s conjecture hold for

$\ell $

-holed graphs and graphs with a small induced circumference.
LINEAR SYSTEMS OF GEOMETRICALLY IRREDUCIBLE PLANE CUBICS OVER FINITE FIELDS
Authors: ASGARLI SHAMIL , GHIOCA DRAGOS 
Published: February 2025

Abstract
We examine the maximum dimension of a linear system of plane cubic curves whose

$\mathbb {F}_q$

-members are all geometrically irreducible. Computational evidence suggests that such a system has a maximum (projective) dimension of

$3$

. As a step towards the conjecture, we prove that there exists a three-dimensional linear system

$\mathcal {L}$

with at most one geometrically reducible

$\mathbb {F}_q$

-member.
Naming North Africans in Latin Christian Chronicles from Medieval Iberia
Authors: Snowden Emma 
Published: February 2025

Abstract
This article examines the words used by Christian chroniclers in medieval Iberia to refer to North Africans. Following the Islamic conquests of the Peninsula in the early eighth century, Iberian Christians increasingly associated North Africans with Islam – and, conversely, Muslims with North Africa. I demonstrate that the term “Moor” reflected a growing tendency over the Middle Ages to collapse religious identity and geographical origins, and further suggest that it was racialized in various ways. In other cases, chroniclers employed scriptural identifiers like “Moabite” and “Hagarene” to distinguish between Muslims from North Africa and those from Iberia. While such terms acknowledged a measure of geopolitical specificity in the present, they simultaneously asserted a kinship between contemporary Muslims and ancient biblical peoples, casting them as religious others, denying their coevalness with Christians, and further racializing them. Finally, I discuss the use of the word “barbarian,” which was sometimes applied to Muslims in general, but was occasionally used to refer to North Africans in particular, drawing on Arabic usage to associate barbarity and lack of civilization with North Africa. Ultimately, I argue that the application of such labels to North Africans and Muslims functioned to displace them geographically and temporally, serving Iberian Christian colonizing impulses and projects over time.
ONCE MORE UNTO THE BREACH: MESOSTIC AND EPITAPH IN CATULLUS POEM 60
Authors: Hawkins Shane 
Published: February 2025

Abstract
In addition to the acrostic–telestic combination natu ceu aes ‘from birth like bronze’, Catullus poem 60 contains the earliest attested Latin mesostic (mi pia ‘dutiful to me’), which runs down its caesuras. The use of pius anticipates the language of aristocratic obligation that is used of Lesbia in the epigrams and is perhaps also a wordplay on the praenomen of Clodia’s father, Appius. The complex acrostics and the syntax of mi pia, along with the setting of poem 59 (in sepulcretis), suggest that poem 60 can be read as a literary epitaph. Additional closural elements in the poem include an allusion to Callimachus and a sphragis in the form of a play on the author’s name.
Plant variety selection using interaction classes derived from Factor Analytic Linear Mixed Models: models with information on genetic relatedness
Authors: Smith Alison B. , Shunmugam Arun S. K. , Butler David G. , Cullis Brian R. 
Published: February 2025

Abstract
The concept of interaction classes (iClasses) for multi-environment trial data was introduced to address the problem of summarising variety performance across environments in the presence of variety by environment interaction (VEI). The approach involves the fitting of a factor analytic linear mixed model (FALMM), with the resultant estimates of factor loadings being used to form groups of environments (iClasses) that discriminate varieties with different patterns of VEI. It is then meaningful to summarise variety performance across environments within iClasses. The iClass methodology was developed with respect to a FALMM in which the genetic effects for different varieties were assumed independent. This was done for pedagogical reasons but it was pointed out that the accuracy of variety selection is greatly enhanced by considering the genetic relatedness of varieties, either via ancestral or genomic information. The focus of the current paper is therefore to extend the iClass approach for FALMMs which incorporate such information. In addition a measure of stability of variety performance across iClasses is defined. The utility of the approach for variety selection is illustrated using a multi-environment trial dataset from the lentil breeding program operated by Agriculture Victoria.
The role of trauma, attachment, and voice-hearer’s appraisals: a latent profile analysis in the AVATAR2 trial
Authors: Marotti Julia , Saunders Rob , Montague Alice , Fornells-Ambrojo Miriam 
Published: February 2025

Abstract

Background
There is evidence that attachment, trauma, and voice appraisals individually impact voice hearing in psychosis, but their intersectional relationship has not been examined. The aim of this study was to identify subgroups of individuals from the intersectional relationship between these factors and examine differences between subgroups on clinical outcomes.

Methods
A latent profile analysis was conducted on baseline data from the AVATAR2 trial (n = 345), to identify statistically distinct subgroups of individuals with psychosis who hear distressing voices based on co-occurring patterns of trauma, fearful attachment, and voice appraisals. The association between profile membership and demographic characteristics, voice severity, posttraumatic stress disorder symptoms, emotional distress, and difficulties with motivation and pleasure was then examined. Experts by experience were consulted throughout the process.

Results
Four profiles were identified: ‘adverse voices and relational trauma’, ‘low malevolent and omnipotent voices’, ‘adverse voices yet low relational trauma’, and ‘high benevolent voices’. Negative voice appraisals occurred in the presence of high and low trauma and attachment adversities. The first profile was associated with being female and/or other non-male genders and had worse voice severity and emotional distress. High adversities and worse emotional distress occurred in the presence of voice benevolence and engagement. Black and South Asian ethnicities were not associated with specific profiles.

Conclusions
The identified profiles had negative and positive voice appraisals associated with higher and lower occurrence of adversities, and different clinical outcomes. These profiles could inform detailed case formulations that could tailor interventions for voice hearers.
Towards the decipherment of Thamudic D: an identification of new glyphs and phoneme values
Authors: Al-Jallad Ahmad 
Published: February 2025

Abstract
The Thamudic D script is only partially deciphered. This article attempts to advance our understanding of the script by identifying all the Thamudic D glyphs and their phonemic values with varying degrees of certainty. It also discusses the major writing formulae associated with this script type and offers a few notes on the language it inscribes.
Room-temperature X-ray powder diffraction data for bosentan monohydrate
Authors: Toro Robert A. , Dugarte-Dugarte Analio J. , Henao José A. , Díaz de Delgado Graciela , Delgado José M. 
Published: February 2025

Abstract
The room-temperature X-ray powder diffraction data for bosentan monohydrate, an API used in the treatment of pulmonary arterial hypertension, is presented. Bosentan monohydrate is monoclinic, P21/c (No. 14), with unit cell parameters a = 12.4520(7) Å, b = 15.110(1) Å, c = 15.0849(9) Å, β = 95.119(5)°, V = 2827.0(3) Å3, Z = 4. All the diffraction maxima recorded were indexed and are consistent with the P21/c space group. The crystal structure of this material corresponds to the phase associated with Cambridge Structural Database entry NEQHEY, which was determined at 123 K. The successful Rietveld refinement, carried out with TOPAS-Academic, showed the single-phase nature of the material and the good quality of the data. A comprehensive analysis of intra- and intermolecular interactions corroborates that the structure is dominated by extensive hydrogen bonding, accompanied by C▬H⋯π and π⋯π interactions. Hirshfeld surface analysis and fingerprint plots indicate that the most important interactions are H⋯H and O⋯H/H⋯O in bosentan and the water molecule and C⋯H/H⋯C interactions in bosentan.
The crosstalk between CREB and PER2 mediates the transition between mania- and depression-like behavior
Authors: Wang Xin-Ling , Ji Yan-Bin , Li Su-Xia , Serchov Tsvetan 
Published: February 2025

Abstract
Bipolar disorder (BD) is a severe psychiatric disorder characterized by alternating manic and depressive episodes. The molecular mechanisms underlying the transition between mania and depression remain unclear. Utilizing a mania animal model induced by ouabain, we observed reduced phosphorylated level of cyclic AMP-responsive element-binding protein (pCREB) and Period (PER)2 expression in the cornu ammonis (CA1) region of the hippocampus, which were restored by lithium treatment. shRNA knockdown of CREB or Per2 in CA1 region induced mania-like behavior, while overexpression of both factors resulted in depression-like behavior. Furthermore, our protein analyses revealed that the upregulation or downregulation of CREB or Per2 influenced each other’s expression. Co-immunoprecipitation results demonstrated that CREB interacts with PER2. Taken together, our data suggest for potential inter-regulatory crosstalk between CREB–PER2 in hippocampal CA1 region, which mediates the transition between mania- and depression-like behaviors.
Hypoxia-induced ATF3 escalates breast cancer invasion by increasing collagen deposition via P4HA1
Authors: Dhamdhere Shruti Ganesh , Bansal Anamika , Singh Pranjal , Kakani Parik , Agrawal Shruti , Samaiya Atul , Shukla Sanjeev 
Published: February 2025

Abstract
Activating transcription factors (ATFs), members of the adaptive-response gene family, participate in cellular processes to aid adaptations in response to extra and/or intracellular changes. In this study, we observed that one of the ATFs, Activating transcription factor 3 (ATF3), is upregulated under hypoxia via alterations in the epigenetic landscape of its promoter, followed by transcriptional upregulation. Under hypoxic conditions, Hypoxia-inducible factor 1-alpha (HIF1ɑ) alleviates methylation at the ATF3 promoter by recruiting TET1 and induces ATF3 transcription. In addition, our RNA-seq analysis showed that ATF3 globally affects transcription under hypoxia and controls the processes of EMT and cancer invasion by stimulating the transcription of Prolyl 4-Hydroxylase Subunit Alpha 1 (P4HA1), an enzyme which enhances invasion-conducive extracellular matrix (ECM) under hypoxic conditions. Prolyl hydroxylases play a critical role in the hydroxylation and deposition of collagen in the extracellular matrix (ECM) during the evolution of cancer, which is necessary for metastasis. Importantly, P4HA1 undergoes alternative splicing under hypoxia, where the inclusion of exon 9a is increased. Interestingly, involvement of ATF3 in P4HA1 splicing was also evident, as binding of ATF3 at intron 9a led to demethylation of this DNA region via recruitment of TET1. Furthermore, we also show that the demethylated DNA region of intron 9a then becomes accessible to CCCTC-binding factor (CTCF). Thus, a cascade of demethylation via ATF3 recruited TET1, followed by increased RNA Pol II pause at intron 9a via CTCF, leads to inclusion of exon 9a. The P4HA1 9a isoform leads to enhanced invasion under hypoxic conditions by increasing deposition of collagen in the ECM. These results reveal a novel hypoxia-induced HIF1ɑ-ATF3-P4HA1 axis which can potentially be exploited as a therapeutic target to impede EMT and ultimately breast cancer invasion.
The p3 peptides (Aβ17-40/42) rapidly form amyloid fibrils that cross-seed with full-length Aβ
Authors: Tian Yao , Torres-Flores Andrea P. , Shang Qi , Zhang Hui , Khursheed Anum , Tahirbegi Bogachan , Pallier Patrick N. , Viles John H. 
Published: February 2025

Abstract
The p3 peptides, Aβ17-40/42, are a common alternative cleavage product of the amyloid precursor protein, and are found in diffuse amyloid deposits of Alzheimer’s and Down Syndrome brains. The p3 peptides have been mis-named ‘non-amyloidogenic’. Here we show p340/42 peptides rapidly form amyloid fibrils, with kinetics dominated by secondary nucleation. Importantly, cross-seeding experiments, with full-length Aβ induces a strong nucleation between p3 and Aβ peptides. The cross-seeding interaction is highly specific, and occurs only when the C-terminal residues are matched. We have imaged membrane interactions with p3, and monitored Ca2+ influx and cell viability with p3 peptide. Together this data suggests the N-terminal residues influence, but are not essential for, membrane disruption. Single particle analysis of TEM images indicates p3 peptides can form ring-like annular oligomers. Patch-clamp electrophysiology, shows p342 oligomers are capable of forming large ion-channels across cellular membranes. A role for p3 peptides in disease pathology should be considered as p3 peptides are cytotoxic and cross-seed Aβ fibril formation in vitro.
Impact of the dispersive patch placement on dissipated power in radiofrequency ablation for pulmonary vein isolation via a virtual patient study
Authors: Anees Minha , Moreno Weidmann Zoraida , Viladés Medel David , Guerra Jose M. , Gerardo-Giorda Luca , Petras Argyrios 
Published: February 2025

Abstract
Radiofrequency ablation (RFA) is a minimally invasive technique for treating arrhythmias by interrupting abnormal electrical signals in the heart. Through a catheter tip, it delivers an alternating current that flows through the heart muscle tissue and the blood to a dispersive patch on the patient’s skin. This study aims to test the hypothesis that the placement of the dispersive patch affects the efficacy and safety of RFA. By optimizing the patch position, the procedure could be made more effective and less risky for patients. A 3D in-silico model, based on patient imaging data, was developed to examine the effects of dispersive patch (DP) positioning on electric field distribution within cardiac tissue and the torso during RFA. We conducted 80 computer simulations using a CT-segmented torso model, exploring various DP and electrode configurations while applying standard (25 W) and high (90 W) power settings. For each configuration, we assessed the effectiveness of the DP in delivering power to cardiac tissue near the electrode. The main finding indicates that DP efficacy is significantly influenced by the current delivered to cardiac tissue. Notably, using an anterior patch during ablation proved more effective for the posterior left atrium compared to a posterior patch.
Mehr als ein Forschungsinstrument: Einsatz des Rupture Resolution
Rating Systems (3RS) in der berufsqualifizierenden Tätigkeit
Authors: Tewes Markus , Waller Emma-Luisa , Kaiser Tim , Brakemeier Eva-Lotta 
Published: February 2025

ZusammenfassungDas Erkennen und der adäquate Umgang mit Problemen in der therapeutischen
Beziehung gelten als zentrale Kompetenzen von Psychotherapeut*innen. Ziel
dieser Studie war es daher, ein Konzept für den Einsatz eines
Fremdbeobachtungsverfahrens zur Beurteilung und Klassifikation von
Allianzbrüchen in die berufsqualifizierende Tätigkeit II des neuen
Approbationsstudiengangs zu überprüfen.In einem 7-stündigen Seminar lernten Studierende die Anwendung des Rupture
Resolution Rating Systems (3RS) sowie zentrale Reparaturstrategien für
Allianzbrüche kennen. Zur Evaluation wurden ein Fragebogen zu den
potenziellen positiven Effekten des 3RS und ein Seminarevaluationsbogen
eingesetzt. Zudem wurden auf Grundlage einer Rollenspielübung Videoanalysen
mit dem 3RS durchgeführt, um Veränderungen in Bezug auf den Umgang mit
Allianzbrüchen bei den Studierenden zu erfassen.An dem 3RS-Seminar nahmen N=35 Studierende teil. Die Anwendung des 3RS wurde
von den Studierenden als hilfreich bewertet, um unter anderem Probleme in
der therapeutischen Allianz besser zu erkennen (74% Zustimmung) und in
Zukunft adäquat mit diesen umgehen zu können (91% Zustimmung). An der
Rollenspielübung beteiligten sich n=8 Studierende. Von diesen zeigten n=3
(37,5%) eine Verbesserung der Effektivität ihrer Reparaturstrategien,
während bei den übrigen Teilnehmer*innen keine Veränderung (n=2, 25%) oder
eine Abnahme der Effektivität (n=3, 37,5%) festgestellt wurde.Das 3RS scheint sich über den Forschungskontext hinaus zur Vermittlung
zentraler Aspekte der therapeutischen Beziehungsgestaltung zu eignen.
Darüber hinaus bietet es das Potenzial, individuelle Veränderung bei
(angehenden) Therapeut*innen aufzuzeigen, wobei für eine verlässliche
Bewertung jedoch eine bessere Standardisierung der Bewertungsgrundlage
erforderlich ist.
Improvement in adenoma detection rate by artificial intelligence-assisted colonoscopy: Multicenter quasi-randomized controlled trial
Authors: Lagström Ronja Maria Birgitta , Bräuner Karoline Bendix , Bielik Julia , Rosen Andreas Weinberger , Crone Julie Gräs , Gögenur Ismail , Bulut Mustafa 
Published: February 2025

AbstractAdenoma detection rate (ADR) is a key performance measure with variability among endoscopists. Artificial intelligence (AI) in colonoscopy could reduce this variability and has shown to improve ADR. This study assessed the impact of AI on ADR among Danish endoscopists of varying experience levels.We conducted a prospective, quasi-randomized, controlled, multicenter trial involving patients aged 18 and older undergoing screening, surveillance, and diagnostic colonoscopy at four centers. Participants were assigned to AI-assisted colonoscopy (GI Genius, Medtronic) or conventional colonoscopy. Endoscopists were classified as experts (> 1000 colonoscopies) or non-experts (≤ 1000 colonoscopies). The primary outcome was ADR. We performed a subgroup analysis stratified on endoscopist experience and a subset analysis of the screening population.A total of 795 patients were analyzed: 400 in the AI group and 395 in the control group. The AI group demonstrated a significantly higher ADR than the control group (59.1% vs. 46.6%, P < 0.001). The increase was significant among experts (59.9% vs. 47.3%, P < 0.002) but not among non-experts. AI assistance significantly improved ADR (74.4% vs. 58.1%, P = 0.003) in screening colonoscopies. Polyp detection rate (PDR) was also higher in the AI group (69.8% vs. 56.2%, P < 0.001). There was no significant difference in the non-neoplastic resection rate (NNRR) (15.1% vs. 17.1%, P = 0.542).AI-assisted colonoscopy significantly increased ADR by 12.5% overall, with a notable 16.3% increase in the screening population. The unchanged NNRR indicates that the higher PDR was due to increased ADR, not unnecessary resections.
Determinants of women small ruminant farmers’ perceptions of climate change impact in Northern Benin
Authors: Dimon Elodie , Toukourou Youssouf , Egah Janvier , Assani Seidou Alassan , Diogo Rodrigue Vivien Cao , Alkoiret Traore Ibrahim 
Published: February 2025

Context The effectiveness of adaptation strategies employed by women small ruminant farmers to combat climate change depends on the accuracy of their perceptions. However, these women’s perceptions are not well understood and are seldom considered in climate change adaptation policies. Aims The aim of this study is to analyze the perceptions of women herders of small ruminants on the effects of climate change in four communes in northern Benin. Methods A total of 120 women farmers were purposefully selected and surveyed. Sociodemographic parameters and the perception rates of these farmers were analyzed using a multinomial logit model to understand the determinants of climate change perception. Key results All surveyed women perceived the effects of climate change, such as delayed rains (73%), early cessation of rains (70%), floods (87.5%), irregular rainfall (62.5%), poor spatial distribution of rains (98%), increased heat (95%), reduced coolness (61.17%), increased strong winds (81%) and wind direction instability (64%) over the past 20 years. Age, education level, farming experience, family size, extension contact, the number of sheep and the number of goats were factors that contributed to evaluating these women’s perceptions of climate change. Conclusions In conclusion, climate change is making livestock farming highly vulnerable. It leads to a scarcity of pastoral resources and a deterioration in animal health. This study recommends promoting training actions for women pastoralists, so that they could be better prepared for preventing and coping with climatic disasters. Implications Future research should compare the differences in adaptation strategies implemented by men and women herders who are better prepared to prevent and cope with climate-related disasters.