bluuebunny/crossref_metadata_2025_split huggingface dataset:
Red cell indices: differentiation between β-thalassemia trait and iron deficiency anemia and application to sickle-cell disease and sickle-cell thalassemia
Authors: Sahli Chaima Abdelhafidh , Bibi Amina , Ouali Faida , Fredj Sondess Hadj , Dakhlaoui Boutheina , Othmani Rym , Laouini Naouel , Jouini Latifa , Ouenniche Fekria , Siala Hajer , Touhami Imed , Becher Mariem , Fattoum Slaheddine , Toumi Nour El Houda , Messaoud Taieb 
Published: June 2013

Abstract

Background: In Tunisia, thalassemia and sickle cell disease represent the most prevalent monogenic hemoglobin disorders with 2.21% and 1.89% of carriers, respectively. This study aims to evaluate the diagnosis reliability of a series of red blood cell indices and parameters in differentiation of beta-thalassemia trait (β-TT) from iron deficiency anemia (IDA) and between homozygous sickle cell disease (SS) and sickle cell-thalassemia (ST).

Methods: The study covered 384 patients divided into three groups. The first one is composed of 145 control group, the second consists of 57 β-TT and 52 IDA subjects and the last one with 88 SS and 42 ST patients. We calculated sensitivity, specificity, positive-predictive values, negative-predictive values, percentage of correctly identified patients and Youden’s index for each indice. We also established new cut-off values by receiver operating characteristic curves for each indice. An evaluation study was performed on another population composed of 106 β-TT, 125 IDA, 31 SS and 17 ST patients.

Results: Srivastava Index, mean corpuscular hemoglobin, red blood cell, Mentzer Index (MI) and mean corpuscular hemoglobin concentration show the highest reliability in discriminating β-TT from IDA with new cut-offs slightly different from those described in literature. Ehsani Index, mean corpuscular volume, MI, Shine and Lal Index and Sirdah Index are the most powerful in the differentiation between SS and ST.

Conclusions: The effectiveness and the simplicity of calculation of these indices make them acceptable and easy to use for differential diagnosis.
Biological characterization of the antiproliferative potential of Co(II) and Sn(IV) coordination compounds in human cancer cell lines: a comparative proteomic approach
Authors: Silva Ana , Luís Daniel , Santos Susana , Silva Joana , Mendo Ana Soraia , Coito Lidia , Silva Telma F.S. , da Silva Maria Fatima C. Guedes , Martins Luísa M.D.R.S. , Pombeiro Armando J.L. , Borralho Pedro M. , Rodrigues Cecília M.P. , Cabral Maria Guadalupe , Videira Paula A. , Monteiro Carolino , Fernandes Alexandra R. 
Published: June 2013

Abstract

Background: The discovery of cisplatin’s antitumor activity led to a great interest in the potential application of coordination compounds as chemotherapeutic agents. It is essential to identify new compounds that selectively inhibit tumor proliferation, evading secondary effects and resistance associated with chemotherapeutics.

Methods: The in vitro antiproliferative potential of an organotin(IV) compound was evaluated using colorectal and hepatocellular carcinoma, mammary gland adenocarcinoma cell lines, and human fibroblasts. Tumor cell death was evaluated by fluorescence microscopy and flow cytometry for the Sn(IV) compound and also for a Co(II) compound bearing 1,10-phenanthroline-5,6-dione as ligand. Comparative proteomic analysis for both compounds was assessed in the colorectal cancer cell line.

Results: The Sn(IV) compound presented a high cytotoxic effect in colorectal and hepatocellular carcinoma cell lines (IC50 of 0.238±0.011 μM, 0.199±0.003 μM, respectively), and a lower cytotoxicity in human fibroblasts. Both compounds induced cell apoptosis and promoted the overexpression of oxidative stress-related enzyme superoxide dismutase [Cu-Zn] (SODC). The Co(II) compound induced a decreased expression of anti-apoptotic proteins (translationally-controlled tumor protein and endoplasmin), and the Sn(IV) compound decreased expression of proteins involved in microtubule stabilization, TCTP, and cofilin-1.

Conclusions: Our data reveals a high in vitro antiproliferative potential against cancer cell lines and a moderate selectivity promoted by the Sn(IV) compound. Proteomic analysis of Sn(IV) and Co(II) compounds in the colorectal cancer cell line allowed an insight to their mechanisms of action, particularly by affecting the expression of proteins typically deregulated in cancer, and also suggesting a promising therapeutic potential for both compounds.
Ethanol Catalytic Oxidation on Ordered Mesoporous CuO/KIT-6 Catalyst
Authors: Zhou Guilin , Zhang Haibing , Xie Hongmei , Wu Mao , Wei Mengying 
Published: June 2013

Abstract
CuO/KIT-6 catalyst was prepared by the excess impregnation method, and used for ethanol selective catalytic oxidation to produce acetaldehyde. The properties of the prepared CuO/KIT-6 catalyst were investigated by XRD and TEM. The results indicate that the synthesized CuO/KIT-6 catalyst still retains highly ordered mesoporous structure with well-dispersed CuO species. The CuO/KIT-6 catalyst shows predominant ethanol selective catalytic oxidation activities. The ethanol conversion and acetaldehyde selectivity of the CuO/KIT-6 catalyst at 275°C are 93.8% and 96.6%, respectively. The CuO/KIT-6 catalyst has high ethanol selective catalytic oxidation activity and acetaldehyde selectivity, which can be attributed to the highly ordered mesoporous structure and well-dispersed CuO species.
Finding the Trustworthiness Nodes from Signed Social Networks
Authors: Li Hui , Zhang Shu , Wang Xia 
Published: June 2013

AbstractOnline social network services have brought a kind of new lifestyle to the world that is parallel to people’s daily offline activities. Social network analysis provides a useful perspective on a range of social computing applications. Social interaction on the Web includes both positive and negative relationships, which is certainly important to social networks. The authors of this article found that the accuracy of the signs of links in the underlying social networks can be predicted. The trust that other users impart on a node is an important attribute of networks. In this article, the authors present a model to compute the prestige of nodes in a trust-based network. The model is based on the idea that trustworthy nodes weigh more. To fulfill this task, the authors first attempt to infer the attitude of one user toward another by predicting signed edges in networks. Then, the authors propose an algorithm to compute the prestige and trustworthiness where the edge weight denotes the trust score. To prove the algorithm’s effectiveness, the authors conducted experiments on the public dataset. Theoretical analysis and experimental results show that this method is efficient and effective.
Racial and Ethnic Disparities in ADHD Diagnosis From Kindergarten to Eighth Grade
Authors: Morgan Paul L. , Staff Jeremy , Hillemeier Marianne M. , Farkas George , Maczuga Steven 
Published: June 2013

OBJECTIVE:
Whether and to what extent racial/ethnic disparities in attention-deficit/hyperactivity disorder (ADHD) diagnosis occur across early and middle childhood is currently unknown. We examined the over-time dynamics of race/ethnic disparities in diagnosis from kindergarten to eighth grade and disparities in treatment in fifth and eighth grade.

METHODS:
Analyses of the nationally representative Early Childhood Longitudinal Study, Kindergarten Class of 1998–1999 (N = 17 100) using discrete-time hazard modeling.

RESULTS:
Minority children were less likely than white children to receive an ADHD diagnosis. With time-invariant and -varying confounding factors statistically controlled the odds of ADHD diagnosis for African Americans, Hispanics, and children of other races/ethnicities were 69% (95% confidence interval [CI]: 60%–76%), 50% (95% CI: 34%–62%), and 46% (95% CI: 26%–61%) lower, respectively, than for whites. Factors increasing children’s risk of an ADHD diagnosis included being a boy, being raised by an older mother, being raised in an English-speaking household, and engaging in externalizing problem behaviors. Factors decreasing children’s risk of an ADHD diagnosis included engaging in learning-related behaviors (eg, being attentive), displaying greater academic achievement, and not having health insurance. Among children diagnosed with ADHD, racial/ethnic minorities were less likely than whites to be taking prescription medication for the disorder.

CONCLUSIONS:
Racial/ethnic disparities in ADHD diagnosis occur by kindergarten and continue until at least the end of eighth grade. Measured confounding factors do not explain racial/ethnic disparities in ADHD diagnosis and treatment. Culturally sensitive monitoring should be intensified to ensure that all children are appropriately screened, diagnosed, and treated for ADHD.
Enrollment in Early Intervention Programs Among Infants Born Late Preterm, Early Term, and Term
Authors: Shapiro-Mendoza Carrie , Kotelchuck Milton , Barfield Wanda , Davin Carol A. , Diop Hafsatou , Silver Michael , Manning Susan E. 
Published: June 2013

OBJECTIVE:
To compare the prevalence of and characteristics associated with early intervention (EI) program enrollment among infants born late preterm (34–36 weeks’ gestation), early term (37–38 weeks’ gestation), and term (39–41 weeks’ gestation).

METHODS:
A Massachusetts cohort of 554 974 singleton infants born during 1998 through 2005 and survived the neonatal period was followed until the third birthday of each infant. Data came from the Pregnancy to Early Life Longitudinal Data System that linked birth certificates, birth hospital discharge reports, death certificates, and EI program enrollment records. We calculated prevalence and adjusted risk ratios to compare differences and understand associations.

RESULTS:
The prevalence of EI program enrollment increased with each decreasing week of gestation before 41 weeks (late preterm [23.5%], early term [14.9%], and term [11.9%]. In adjusted analyses, the strongest predictors of EI enrollment (adjusted risk ratio ≥1.20) for all gestational age groups were male gender, having a congenital anomaly, and having mothers who were ≥40 years old, nonhigh school graduates, and recipients of public insurance.

CONCLUSIONS:
Infants born late preterm and early term have higher prevalence of EI program services enrollment than infants born at term, and may benefit from more frequent monitoring for developmental delays or disabilities.
Implementation of a Parental Tobacco Control Intervention in Pediatric Practice
Authors: Winickoff Jonathan P. , Nabi-Burza Emara , Chang Yuchiao , Finch Stacia , Regan Susan , Wasserman Richard , Ossip Deborah , Woo Heide , Klein Jonathan , Dempsey Janelle , Drehmer Jeremy , Hipple Bethany , Weiley Victoria , Murphy Sybil , Rigotti Nancy A. 
Published: June 2013

OBJECTIVE:
To test whether routine pediatric outpatient practice can be transformed to assist parents in quitting smoking.

METHODS:
Cluster RCT of 20 pediatric practices in 16 states that received either CEASE intervention or usual care. The intervention gave practices training and materials to change their care delivery systems to provide evidence-based assistance to parents who smoke. This assistance included motivational messaging; proactive referral to quitlines; and pharmacologic treatment of tobacco dependence. The primary outcome, assessed at an exit interview after an office visit, was provision of meaningful tobacco control assistance, defined as counseling beyond simple advice (discussing various strategies to quit smoking), prescription of medication, or referral to the state quitline, at that office visit.

RESULTS:
Among 18 607 parents screened after their child’s office visit between June 2009 and March 2011, 3228 were eligible smokers and 1980 enrolled (999 in 10 intervention practices and 981 in 10 control practices). Practices’ mean rate of delivering meaningful assistance for parental cigarette smoking was 42.5% (range 34%–66%) in the intervention group and 3.5% (range 0%–8%) in the control group (P &lt; .0001). Rates of enrollment in the quitline (10% vs 0%); provision of smoking cessation medication (12% vs 0%); and counseling for smoking cessation (24% vs 2%) were all higher in the intervention group compared with the control group (P &lt; .0001 for each).

CONCLUSIONS:
A system-level intervention implemented in 20 outpatient pediatric practices led to 12-fold higher rates of delivering tobacco control assistance to parents in the context of the pediatric office visit.
SnO2:F with Very High Haze Value and Transmittance in Near Infrared Wavelength for Use as Front Transparent Conductive Oxide Films in Thin-Film Silicon Solar Cells
Authors: Isshiki Masanobu , Ishikawa Yasuko , Ikeda Toru , Oyama Takuji , Odaka Hidefumi , Sichanugrist Porponth , Konagai Makoto 
Published: June 2013

ABSTRACTLow sheet resistance (high mobility) with high transmittance in all wavelength is required for front TCO. High haze value is also required for effective light trapping. For this purpose, we have combined F-doped SnO2(FTO) with high mobility deposited by LPCVD and reactive ion etching (RIE) processed glass substrate. However, two problems have been found. (1) The mobility of FTO on RIE substrate dropped from that on flat glass (75 to 36 cm2/Vs). To avoid this drop, thicker film is needed. (2) To keep high transmittance with thicker film, lower carrier concentration is needed. But the mobility dropped with lower carrier concentration. In order to solve these constrains, we have adopted a stacked structure using thick non-doped layer of 2700 nm and thin F-doped layer of 500 nm. With this novel approach, we have successfully achieved the high mobility (80 cm2/Vs), low carrier concentration (2.2x1019/cm3) and high haze value (77% at wavelength of 1000 nm) at the same time. This new developed high-haze SnO2is a new promising TCO for thin-film Si solar cells.
Microstructure Characterization of Amorphous Silicon Films by Effusion Measurements of Implanted Helium
Authors: Beyer W. , Hilgers W. , Lennartz D. , Maier F.C. , Nickel N.H. , Pennartz F. , Prunici P. 
Published: June 2013

ABSTRACTAn important property of thin film silicon and related materials is the microstructure which may involve the presence of interconnected and isolated voids. We report on effusion measurements of implanted helium (He) to detect such voids. Several series of hydrogenated and unhydrogenated amorphous silicon films prepared by the methods of plasma deposition, hot wire deposition and vacuum evaporation were investigated. The results show common features like a He effusion peak at low temperatures attributed to He out-diffusion through a compact material or through interconnected voids, and a He effusion peak at high temperatures attributed to He trapped in isolated voids. While undoped plasma-grown device-grade hydrogenated amorphous silicon (a-Si:H) films show a rather low concentration of such isolated voids, its concentration can be rather high in doped a-Si:H, in unhydrogenated evaporated material and others.
Employing μc-SiOX:H as n-Type Layer and Back TCO Replacement for High-Efficiency a-Si:H/μc-Si:H Tandem Solar Cells
Authors: Liang S.W. , Hsu C.H. , Tseng Y.W. , Lin Y.P. , Tsai C.C. 
Published: June 2013

ABSTRACTThe n-type hydrogenated microcrystalline silicon oxide (μc-SiOX:H(n)) films with different stoichiometry have been successfully prepared by varying the CO2-to-SiH4flow ratio in the PECVD system. By using the μc-SiOX:H(n) as a replacement for μc-Si:H(n) and ITO, the conversion efficiency of μc-Si:H single-junction and a-Si:H/μc-Si:H tandem cells were improved to 6.35% and 10.15%, respectively. The major improvement of the short circuit current density (JSC) and these cell efficiencies were originated from the increased optical absorption, which was confirmed by the quantum efficiency measurement showing increased response in the long-wavelength region. Moreover, the all PECVD process except the metal contact simplified the fabrication and might benefit the industrial production.
Characterization of Boron Doped Amorphous Silicon Films by Multiple Internal Reflection Infrared Spectroscopy
Authors: Ross N. , Shrestha K. , Chyan O. , Littler C. L , Lopes V. C. , Syllaios A. J. 
Published: June 2013

ABSTRACTIn this study, we employed Multiple Internal Reflection Infrared Spectroscopy (MIR-IR) to characterize chemical bonding structures of boron doped hydrogenated amorphous silicon (a-Si:H(B)). This technique has been shown to provide over a hundred fold increase of detection sensitivity when compared with conventional FTIR. Our MIR-IR analyses reveal an interesting counter-balance relationship between boron-doping and hydrogen-dilution growth parameters in PECVD-grown a-Si:H. Specifically, an increase in the hydrogen dilution ratio (H2/SiH4) was found to cause the increase in the Si-H bonding and a decrease in the B-H and SiH2 bonding, as evidenced by the changes in corresponding IR absorption peaks. In addition, although a higher boron dopant gas concentration was seen to increase the BH and SiH2 bonding, it also resulted in the decrease of the most stable SiH bonding configuration. The new chemical bonding information of a-Si:H thin film was correlated with the various boron doping mechanisms proposed by theoretical calculations.
On the Origin of the Urbach Rule and the Urbach Focus
Authors: Guerra J. A. , Montañez L. , De Zela F. , Winnacker A. , Weingärtner R. 
Published: June 2013

ABSTRACTA simple derivation of sub-bandgap exponential tails and fundamental absorption equations ruling the optical absorption of amorphous semiconductors are presented following the frozen phonon model. We use the Kubo-Greenwood formula to describe the average transition rate for the optical absorption process. Asymptotic analysis leads to the commonly observed exponential tail as well as the Tauc expression for the fundamental absorption. We test our theoretical results with experimental absorption coefficients of amorphous Si:H, SiC:H, AlN and SiN. The validity of the Urbach focus concept is evaluated.
Nutritional Factors and Preservation of C-Peptide in Youth With Recently Diagnosed Type 1 Diabetes
Authors: Mayer-Davis Elizabeth J. , Dabelea Dana , Crandell Jamie L. , Crume Tessa , D’Agostino Ralph B. , Dolan Lawrence , King Irena B. , Lawrence Jean M. , Norris Jill M. , Pihoker Catherine , The Natalie 
Published: June 2013

OBJECTIVE
To test the novel hypothesis that nutritional factors previously associated with type 1 diabetes etiology or with insulin secretion are prospectively associated with fasting C-peptide (FCP) concentration among youth recently diagnosed with type 1 diabetes.

RESEARCH DESIGN AND METHODS
Included were 1,316 youth with autoantibody-positive type 1 diabetes who participated in the SEARCH for Diabetes in Youth study (baseline disease duration, 9.9 months; SD, 6.3). Nutritional exposures included breastfeeding and age at introduction of complementary foods, baseline plasma long-chain omega-3 fatty acids including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), vitamin D, vitamin E, and, from a baseline food frequency questionnaire, estimated intake of the branched-chain amino acid leucine and total carbohydrate. Multiple linear regression models were conducted to relate each nutritional factor to baseline FCP adjusted for demographics, disease-related factors, and other confounders. Prospective analyses included the subset of participants with preserved β-cell function at baseline (baseline FCP ≥0.23 ng/mL) with additional adjustment for baseline FCP and time (mean follow-up, 24.3 months; SD, 8.2; n = 656). FCP concentration was analyzed as log(FCP).

RESULTS
In adjusted prospective analyses, baseline EPA (P = 0.02), EPA plus DHA (P = 0.03), and leucine (P = 0.03) were each associated positively and significantly with FCP at follow-up. Vitamin D was unexpectedly inversely associated with FCP (P = 0.002).

CONCLUSIONS
Increased intake of branched-chain amino acids and long-chain omega-3 fatty acids may support preservation of β-cell function. This represents a new direction for research to improve prognosis for type 1 diabetes.
The development and genesis of a small thaw lake filling the Skaliska Basin during the Late Glacial and Holocene
Authors: Stachowicz-Rybka Renata , Obidowicz Andrzej 
Published: June 2013

ABSTRACT
The northern part of the Mazury Lake District is marked by the presence of a depression described as the Skaliska Basin. At the end of the Pleistocene, the Skaliska Basin was the site of functioning of a thaw lake, within series of laminated clayey sediments were formed. The surface of the clayey sediments was overlain by a sandy fan. Blocks of dead ice underlying the fan and the overlying surface of the clayey sediments were the origin of small isolated water basins. Since the Allerod they were filled with limnic sediments, passing into peats towards the upper part. In order to reconstruct the vegetational history of the Skaliska Basin and the conditions of sedimentation of the lacustrine gyttjas and peats, several sections were obtained from such basins and subjected to examination of plant macroremains, palaeolimnological analysis and AMS dating. Sedimentation of lacustrine sediments began with sands with an admixture of silt and peat. The beginning of sedimentation of lacustrine sands of aeolian origin falls within the Allerod, whereas the end of that process in ca the middle of the Preboreal. Sands are frequently overlain by a strongly decomposed lacustrine dy sediment. Subsequently a sequence of detritus gyttja accumulated. The complex of gyttjas is interbedded with occasional Scirpo-Typheti peats. Sedimentation of lacustrine sediments is followed by accumulation of peats formed within communities with tall sedges. These communities, according to their compoition, correspond to the associations of Cicuto- Caricetum pseudocyperi Boer. et Siss. and Caricetum elatae Koch. The upper part comprises peats resembling the present-day community of Sphagnum centrale, displaying features of a transition bog. Also the occurrence of Eriophorum vaginatum confirms changes towards ombrotrophic conditions. The uppermost part of the sections often comprises heavily decomposed peat with components no longer identifiable by macroscopic analysis.
Cladocera record from Budzewo (Skaliska Basin, north-eastern Poland)
Authors: Gąsiorowski Michał 
Published: June 2013

ABSTRACT
The sediment sequence from Budzewo (Skaliska Basin, north-eastern Poland) contains cladoceran records beginning from the early Holocene. A total of 33 Cladocera taxa were identified in the entire sequence. The cladoceran fauna of the initial stage of palaeolake history in the Preboreal shows high similarity to early Holocene Estonian and Scandinavian records. Benthic Alonella nana was dominant at that time. After that, probably during the Boreal and early Atlantic periods, Cladocera species diversity increased and planktonic forms (bosminas) became dominant, pointing to a rise of water level. The species composition indicates that the lake was meso- to eutrophic. The lake began to shallow during the middle Atlantic. The process was completed in the Subboreal and the lake transformed into a bog. The fall in water level and finally the terrestrialization of the lake is correlated with similar processes recorded in other sediment sequences in northern Poland, suggesting that this event may have been driven by regional factors such as lower precipitation.
Laparoscopic conservative treatment of colo-vesical fistulas following trauma and diverticulitis: report of two different cases
Authors: Giovanni Cochetti , Emanuele Lepri , Emanuele Cottini , Roberto Cirocchi , Corsi Alessia , Francesco Barillaro , Andrea Boni , Rosa Mancuso , Pohja Solajd , Ettore Mearini 
Published: June 2013

Abstract