bluuebunny/crossref_metadata_2025_split huggingface dataset:
High‐resolution compressive channel estimation for broadband wireless communication systems
Authors: Gui Guan , Peng Wei , Adachi Fumiyuki 
Published: December 2012

SUMMARYBroadband channel is often characterized by a sparse multipath channel where dominant multipath taps are widely separated in time, thereby resulting in a large delay spread. Accurate channel estimation can be done by sampling received signal with analog‐to‐digital converter (ADC) at Nyquist rate and then estimating all channel taps with high resolution. However, these Nyquist sampling‐based methods have two main disadvantages: (i) demand of the high‐speed ADC, which already exceeds the capability of current ADC, and (ii) low spectral efficiency. To solve these challenges, compressive channel estimation methods have been proposed. Unfortunately, those channel estimators are vulnerable to low resolution in low‐speed ADC sampling systems. In this paper, we propose a high‐resolution compressive channel estimation method, which is based on sampling by using multiple low‐speed ADCs. Unlike the traditional methods on compressive channel estimation, our proposed method can approximately achieve the performance of lower bound. At the same time, the proposed method can reduce communication cost and improve spectral efficiency. Numerical simulations confirm our proposed method by using low‐speed ADC sampling. Copyright © 2012 John Wiley & Sons, Ltd.
Constructing a VANET based on cluster chains
Authors: Xiaonan Wang , Huanyan Qian 
Published: December 2012

SUMMARYThe paper proposes a scheme on constructing a vehicular ad‐hoc network based on cluster chains. In the cluster construction algorithm, the distance from a potential cluster head to its neighbor cluster associate node is used as a metric to elect a cluster head, so the number of the cluster heads is minimized. In the cluster‐chain construction algorithm, the distance from a potential cluster associate node to its neighbor cluster head is used as a metric to elect a cluster associate node, so the number of the nodes in a cluster chain is minimized. The cluster/cluster‐chain repair algorithm maintains the cluster/cluster‐chain stability. The cluster/cluster‐chain merging algorithm has no effects on the topology of the corresponding cluster chains, so the cluster‐chain stability is enhanced. The performances of the proposed scheme and the existing scheme are analyzed, and the performance parameters include the cluster size, the cluster formation delay, the cluster stability, and the cluster‐chain stability. And the analytical results show that the performance of the proposed scheme is better. Copyright © 2012 John Wiley & Sons, Ltd.
Immediate cytology improves accuracy and decreases complication rate in real‐time computed tomography‐guided needle lung biopsy
Authors: Tachibana Keisei , Nakazato Yoshimasa , Tsuchida Shigeru , Kazama Toshifumi , Minato Koichi , Yoshida Tsutomu , Fujita Atsushi , Horikoshi Hiroyuki , Tanaka Ryota , Iijima Misa , Goya Tomoyuki 
Published: December 2012

Computed tomography‐guided percutaneous transthoracic needle biopsy (CTNB) of the lung is a well‐established diagnostic technique for the evaluation of thoracic lesions. At our institution, we have performed real‐time CTNB using automated biopsy needles since 1998 and we introduced immediate cytology in 2004. We evaluate immediate cytology in CTNB to increase the diagnostic accuracy and to reduce the number of inadequate specimens.We retrospectively reviewed a consecutive series of 270 patients (group A: 98 patients before introduction, group B: 172 patients after introduction) who underwent CTNB between 2002 and 2009. We compared the diagnostic performance and the complication rates between two groups.There were no significant differences between groups A and B in patient and lesion characteristics. The rates of one time biopsy were significantly different: 56.1% (55/98) in group A and 69.2% (119/172) in group B. The rates of diagnostic accuracy in groups A and B were 79.6% (78/98) and 94.8% (163/172), respectively; the sensitivity were 74.0% (57/77) and 94.1% (127/135); the specificity were 100% (21/21) and 97.3% (36/37); the rates of major complications were 14.3% (14/98) and 2.9% (5/172). Group B had significantly higher diagnostic accuracy, sensitivity, and a lower complication rate in comparison with group A.CTNB with immediate cytology can improve diagnostic performance and decrease the complication rate. These improvements may help make CTNB less of a burden for patients. Diagn. Cytopathol. 2013;41:1063–1068. © 2012 Wiley Periodicals, Inc.
A Single Source Precursor Route to Group 13 Homo‐ and Heterometallic Oxides as Highly Active Supports for Gold‐Catalyzed Aerobic Epoxidation of trans‐Stilbene
Authors: Mishra Shashank , Mendez Violaine , Jeanneau Erwann , Caps Valérie , Daniele Stéphane 
Published: December 2012

AbstractA new Mitsubishi‐type of star‐shaped homoleptic derivative of indium(III), In4(mdea)6 (2, mdeaH2 = N‐methyldiethanolamine), was synthesized by the chloro–aminoalkoxo exchange reaction of a heteroleptic complex In6Cl6(mdea)6 (1) and used as a facile single source molecular precursor for the sol–gel preparation of high surface area indium oxide. Successful deposition of gold nanoparticles (1 wt.‐%) of average size 3.3 nm on the above metal oxide by using HAuCl4·3H2O afforded a highly efficient Au/In2O3 catalyst for the aerobic epoxidation of trans‐stilbene at low temperature. The above single source precursor approach was further extended to obtain other group 13 homo‐ and heterometallic oxides, namely, α‐Ga2O3, β‐Ga2O3 and Al4Ga2O9, as highly active supports for gold catalysts. The obtained Au/M2O3 (M = Ga, In) and Au/Al4Ga2O9 catalysts were thoroughly characterized by using several physicochemical techniques such as XRD, high resolution transmission electron microscopy (HR‐TEM), energy‐dispersive X‐ray (EDX) spectroscopy, and X‐ray photoelectron spectroscopy (XPS). A comparative study of the above catalysts for the model aerobic oxidation of stilbene in methylcyclohexane was undertaken.
Pd‐Catalyzed Chemoselective Cross‐Coupling Reaction of Triaryl‐ or Triheteroarylbismuth Compounds with 3,6‐Dihalopyridazines
Authors: Urgin Karène , Aubé Christophe , Pipelier Muriel , Blot Virginie , Thobie‐Gautier Christine , Sengmany Stéphane , Lebreton Jacques , Léonel Eric , Dubreuil Didier , Condon Sylvie 
Published: December 2012

AbstractThe cross‐coupling reactions of 3,6‐dihalopyridazines with triaryl‐ or triheteroarylbismuth compounds were performed under palladium catalysis. The reaction was highly chemoselective, affording functionalized aryl‐ or heteroarylpyridazinyl chlorides in moderate to good yields.
Conjugate Addition of Indoles and Pyrroles to Dihydronitronaphthalenes in Water: Synthesis of 3,4‐Fused Tetrahydro‐β‐carbolines
Authors: Malhotra Rajesh , Ghosh Rajib , Dey Tushar K. , Chakrabarti Sagar , Ghosh Amit , Dutta Swarup , Asijaa Sonika , Roy Subho , Dutta Shantanu , Basu Sourav , Hajra Saumen 
Published: December 2012

AbstractA catalyst‐free conjugate addition of indoles and pyrroles to 1,2‐dihydro‐3‐nitronaphthalenes in water has been developed. A variety of indoles containing electron‐rich and ‐deficient functional groups including aza‐indoles and pyrroles reacted smoothly with a number of dihydro‐3‐nitronaphthalenes, especially bromo derivatives. For structural elaboration, the bromo functionality (dihydronitronaphthalene unit as well as indolyl unit) of the addition products was utilized for Suzuki coupling reactions and provided moderate to good yields of the desired coupling compounds. The utility of the method was further demonstrated by the synthesis of 3,4‐fused tetrahydro‐β‐carbolines, a new class of compounds, from the addition products through reduction of the nitro group to the amine and subsequent Pictet–Spengler cyclization.
The impairment of HCCS leads to MLS syndrome by activating a non‐canonical cell death pathway in the brain and eyes
Authors: Indrieri Alessia , Conte Ivan , Chesi Giancarlo , Romano Alessia , Quartararo Jade , Tatè Rosarita , Ghezzi Daniele , Zeviani Massimo , Goffrini Paola , Ferrero Ileana , Bovolenta Paola , Franco Brunella 
Published: December 2012

AbstractMitochondrial‐dependent (intrinsic) programmed cell death (PCD) is an essential homoeostatic mechanism that selects bioenergetically proficient cells suitable for tissue/organ development. However, the link between mitochondrial dysfunction, intrinsic apoptosis and developmental anomalies has not been demonstrated to date. Now we provide the evidence that non‐canonical mitochondrial‐dependent apoptosis explains the phenotype of microphthalmia with linear skin lesions (MLS), an X‐linked developmental disorder caused by mutations in the holo‐cytochrome c‐type synthase (HCCS) gene. By taking advantage of a medaka model that recapitulates the MLS phenotype we demonstrate that downregulation of hccs, an essential player of the mitochondrial respiratory chain (MRC), causes increased cell death via an apoptosome‐independent caspase‐9 activation in brain and eyes. We also show that the unconventional activation of caspase‐9 occurs in the mitochondria and is triggered by MRC impairment and overproduction of reactive oxygen species (ROS). We thus propose that HCCS plays a key role in central nervous system (CNS) development by modulating a novel non‐canonical start‐up of cell death and provide the first experimental evidence for a mechanistic link between mitochondrial dysfunction, intrinsic apoptosis and developmental disorders.
Determining the impact of the Holocene highstand at the coastal‐fluvial interface, Shoalhaven River, south‐eastern Australia
Authors: Kermode Stephanie J. , Gibling Martin R. , Jones Brian G. , Cohen Tim J. , Price David M. , Daley James S. 
Published: December 2012

ABSTRACTWith enhanced rates of sea‐level rise predicted for the next century, the upstream extent of sea‐level influence across coastal plains is a topic of public importance. Australian coastal rivers provide a testing ground for exploring this issue because the area is tectonically stable, was not glaciated, and experienced a Holocene highstand between 7.4 and 2 ka of up to 1.5 m above Australian Height Datum (AHD). In the Shoalhaven River of New South Wales, investigation of a confined bedrock reach at Wogamia, 32 km inland, has identified a unit of dark, cohesive silt and sand with marine diatoms, shell fragments, and enhanced pyrite content, interpreted as estuarine. The unit is up to 13 m thick, thickens downstream, and is overlain by fluvial channel and floodplain deposits. The estuarine unit on‐laps a remnant Pleistocene terrace and extends to approximately +2.2 m AHD. Optically stimulated luminescence (OSL) and radiocarbon ages suggest that estuarine deposition commenced prior to 7.8 ka calbp, predating the highstand by ~ 500 years, and that marine influence in the area continued to 5.3 ± 0.7 ka. During this period, a delta probably persisted at Wogamia, where a narrow upstream reach opens out, and subsequently advanced to fill the broad Shoalhaven coastal embayment. Although the effect of sea‐level rise depends on many factors, the results suggest that, during a highstand at or above present sea level, a strong marine influence may extend for tens of kilometres inland and penetrate confined bedrock reaches landward of coastal embayments. Copyright © 2013 John Wiley & Sons, Ltd.
THE EFFECTS OF EARNED INCOME TAX CREDIT PAYMENT EXPANSION ON MATERNAL SMOKING
Authors: Averett Susan , Wang Yang 
Published: December 2012

ABSTRACTThe Earned Income Tax Credit is the largest antipoverty program in the USA. In 1993, the Earned Income Tax Credit benefit levels were changed significantly based on the number of children in the family such that families with two or more children experienced an exogenous expansion in their incomes. Using data from the National Longitudinal Survey of Youth 1979 cohort, we use a triple‐difference plus fixed effects framework to examine the effect of this change on the probability of smoking among low‐educated mothers. We find that the probability of smoking for White low‐educated mothers of two or more children significantly decreased relative to those with only one child, and this result is robust to various specification tests. This result provides new evidence on the protective effect of income on health through changes in a health‐related behavior and therefore has important policy implications. Copyright © 2012 John Wiley & Sons, Ltd.
Informal patient payments in maternity hospitals in Kiev, Ukraine
Authors: Stepurko Tetiana , Pavlova Milena , Levenets Olena , Gryga Irena , Groot Wim 
Published: December 2012

ABSTRACTMaternity care in Ukraine is a government priority. However, it has not undergone substantial changes since the collapse of the Soviet Union. Similar to the entire health care sector in Ukraine, maternity care suffers from inefficient funding, which results in low quality and poor access to services. The objective of this paper is to explore the practice of informal payments for maternity care in Ukraine, specifically in cases of childbirth in Kiev maternity hospitals. The paper provides an ethnographic study on the consumers' and providers' experiences with informal payments. The results suggest that informal payments for childbirth are an established practice in Kiev maternity hospitals. The bargaining process between the pregnant woman (incl. her partner) and the obstetrician is an important part of the predelivery arrangement, including the informal payment. To deal with informal payments in Kiev maternity hospitals, there is a need for the following: (i) regulation of the “quasi‐official” patient payments at the health care facility level; and (ii) improvement of professional ethics through staff training. These strategies should be coupled with improved governance of the health care sector in general, and maternity care in particular in order to attain international quality standards and adequate access to facilities. Copyright © 2012 John Wiley & Sons, Ltd.
Involvement of trigeminal ganglionic Nav1.7 in hyperalgesia of inflamed temporomandibular joint is dependent on ERK1/2 phosphorylation of glial cells in rats
Authors: Bi R‐Y. , Kou X‐X. , Meng Z. , Wang X‐D. , Ding Y. , Gan Y‐H. 
Published: December 2012

AbstractBackgroundInflammation is a major cause of temporomandibular disorder‐related pain. The Nav1.7 sodium channel has a critical function in pain perceptions. However, whether and how Nav1.7 in the trigeminal ganglion is involved in temporomandibular joint (TMJ) inflammatory pain remains to be examined.MethodsTMJ inflammation was induced by complete Freund's adjuvant in female rats. The expression of trigeminal ganglionic Nav1.7 and other sodium channels was examined using real‐time polymerase chain reaction or Western blotting. Immunohistofluorescence with fluorescent retrograde neuronal tracer DiI was used to confirm Nav1.7 in the trigeminal neurons innervating TMJ. The functions of trigeminal ganglionic Nav1.7 and extracellular signal‐regulated kinase 1/2 (ERK1/2) phosphorylation were blocked with the microinjection of the Nav1.7 antibody or U0126 into the trigeminal ganglion. Head withdrawal threshold and food intake was measured to evaluate TMJ nociceptive responses.ResultsTMJ inflammation significantly up‐regulated Nav1.7 mRNA and protein; however, the mRNA of Nav1.3 was not affected and those of Nav1.8 and Nav1.9 were only slightly up‐regulated. TMJ inflammation specifically induced Nav1.7 in the neurons innervating TMJ. In addition, blocking the Nav1.7 function significantly attenuated the hyperalgesia of the inflamed TMJ. Moreover, TMJ inflammation up‐regulated ERK1/2 phosphorylation only in the glials; blocking ERK1/2 phosphorylation in the glials blocked Nav1.7 up‐regulation in the neurons and correspondingly attenuated the hyperalgesia of the inflamed TMJ.ConclusionsTrigeminal ganglionic Nav1.7 has an important function in the hyperalgesia of the inflamed TMJ, which is dependent on the communication with the satellite glials.
Effect of intrathecal baclofen on evoked pain perception: An evoked potentials and quantitative thermal testing study
Authors: Kumru H. , Kofler M. , Flores M.C. , Portell E. , Robles V. , Leon N. , Vidal J. 
Published: December 2012

AbstractBackground and ObjectivesSomatic antinociceptive effects of baclofen have been demonstrated in animal models. We hypothesized that if enhanced thermal or pain sensitivity is produced by loss of gamma‐aminobutyric acid (GABA)‐ergic tone in the central nervous system, spinal administration of GABA agonists might be predicted to be effective in thermal and/or pain perception changes and pain‐related evoked potentials in candidates for intrathecal baclofen (ITB) treatment.MethodsEleven patients with severe spinal cord injury (SCI) who suffered from severe spasticity were evaluated during a 50‐μg ITB bolus test. Warm and heat pain thresholds, evoked heat pain perception, and contact heat‐evoked potentials (CHEPs) were determined above SCI level from the right and left sides. Nine age‐ and gender‐matched healthy volunteers undergoing repeat testing without any placebo injection served as control group.ResultIn patients, heat pain perception threshold increased, and evoked pain perception and amplitude of CHEPs decreased significantly after ITB bolus application in comparison with baseline (p < 0.005), with no change in warm perception threshold. In controls, no significant changes were observed in repeat testing over time.ConclusionOur findings indicate that ITB modulates heat pain perception threshold, evoked heat pain perception and heat pain‐related evoked potentials without inducing warm perception threshold changes in SCI patients. This phenomenon should be taken into account in the clinical evaluation and management of pain in patients receiving baclofen.
Shedding light on diatom photonics by means of digital holography
Authors: Di Caprio Giuseppe , Coppola Giuseppe , Stefano Luca De , Stefano Mario De , Antonucci Alessandra , Congestri Roberta , Tommasi Edoardo De 
Published: December 2012

AbstractDiatoms are among the dominant phytoplankters in the world's oceans, and their external silica investments, resembling artificial photonic crystals, are expected to play an active role in light manipulation. Digital holography allowed studying the interaction with light of Coscinodiscus wailesii cell wall reconstructing the light confinement inside the cell cytoplasm, condition that is hardly accessible via standard microscopy. The full characterization of the propagated beam, in terms of quantitative phase and intensity, removed a long‐standing ambiguity about the origin of the light confinement. The data were discussed in the light of living cell behavior in response to their environment. (© 2014 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Behavior of plaster of Paris‐calcium carbonate composite as bone substitute. A study in rats
Authors: Dewi Anne Handrini , Ana Ika Dewi , Wolke Joop , Jansen John 
Published: December 2012

AbstractCalcium sulfate, also known as plaster of Paris (POP), is probably the oldest biomaterial used for bone grafting and considered to be a fast degradable material that allows complete resorption before the bone defect area is completely filled by new bone. The aim of this study was to investigate the possibility to combine POP with calcium carbonate in order to increase the the osteoconductivity of this material. Twenty four male Sprague Dawley rats, 5‐months‐old and weighing 300–350 g, were used in the study. Various treatment groups were created by the implantation of cylindrical samples of POP‐100, POP‐075 and POP‐050 into the femoral condyles. After 1 and 4 weeks of implantation, rats were sacrificed and the implanted areas and the surrounding tissue were retrieved for histological analysis. The study was completed by anin vitroexperiment, which included the soaking of the experimental materials into simulated body fluid. The results indicated that the composites were appropriate to be used as bone grafting material. The incorporation of CaCO3into POP did decrease the degradation rate of the cements and induced faster bone formation, thus provides promising properties to this material. © 2012 Wiley Periodicals, Inc. J Biomed Mater Res Part A, 2013.
Counter‐Interrogation Strategies when Anticipating Questions on Intentions
Authors: Clemens Franziska , Granhag Pär Anders , Strömwall Leif A. 
Published: December 2012

AbstractThe present experimental study adds to the emerging line of psycholegal research focusing on true and false intentions. It is the first to examine mock suspects' (N = 120) counter‐interrogation strategies in investigative interviews in which they anticipate questions on their intentions. As planning is an inherent part of many intentions, mock suspects were, in addition to questions on their intentions, asked a set of questions that pertained to the planning phase in which they formed their intentions. Besides ratings of the anticipation and difficulty of the questions, participants were asked to provide their principal strategy for being perceived as truthful. Both truth tellers and liars perceived the questions on the planning phase as significantly more unanticipated than the questions on their intentions. Furthermore, liars perceived the questions on the planning phase as more difficult to answer than did truth tellers. Liars and truth tellers differed with respect to their principal strategy employed for being perceived as truthful. Liars' most commonly used strategy was to stick to the cover story, whereas truth tellers' most common strategy was to be honest. The results are discussed in relation to the unanticipated questions approach and psychological concepts such as the illusion of transparency. Copyright © 2012 John Wiley & Sons, Ltd.
Comparative study of lacosamide and classical sodium channel blocking antiepileptic drugs on sodium channel slow inactivation
Authors: Niespodziany Isabelle , Leclère Nathalie , Vandenplas Catherine , Foerch Patrik , Wolff Christian 
Published: December 2012

AbstractMany antiepileptic drugs (AEDs) exert their therapeutic activity by modifying the inactivation properties of voltage‐gated sodium (Nav) channels. Lacosamide is unique among AEDs in that it selectively enhances the slow inactivation component. Although numerous studies have investigated the effects of AEDs on Nav channel inactivation, a direct comparison of results cannot be made because of varying experimental conditions. In this study, the effects of different AEDs on Nav channel steady‐state slow inactivation were investigated under identical experimental conditions using whole‐cell patch‐clamp in N1E‐115 mouse neuroblastoma cells. All drugs were tested at 100 μM, and results were compared with those from time‐matched control groups. Lacosamide significantly shifted the voltage dependence of Nav current (INa) slow inactivation toward more hyperpolarized potentials (by −33 ± 7 mV), whereas the maximal fraction of slow inactivated channels and the curve slope did not differ significantly. Neither SPM6953 (lacosamide inactive enantiomer), nor carbamazepine, nor zonisamide affected the voltage dependence of INa slow inactivation, the maximal fraction of slow inactivated channels, or the curve slope. Phenytoin significantly increased the maximal fraction of slow inactivated channels (by 28% ± 9%) in a voltage‐independent manner but did not affect the curve slope. Lamotrigine slightly increased the fraction of inactivated currents (by 15% ± 4%) and widened the range of the slow inactivation voltage dependence. Lamotrigine and rufinamide induced weak, but significant, shifts of INa slow inactivation toward more depolarized potentials. The effects of lacosamide on Nav channel slow inactivation corroborate previous observations that lacosamide has a unique mode of action among AEDs that act on Nav channels. © 2012 Wiley Periodicals, Inc.