bluuebunny/crossref_metadata_2025_split huggingface dataset:
An Iterative Detection and Removal Method for Detecting Spatial Clusters of Different Densities
Authors: Liu Qiliang , Tang Jianbo , Deng Min , Shi Yan 
Published: March 2014

AbstractA fundamental element of exploratory spatial data analysis is the discovery of clusters in a spatial point dataset. When clusters with distinctly different local densities exist, the determination of suitable density level is still an unsolved problem. On that account, an iterative detection and removal method is proposed in this study. In each step of the novel method, there are two stages. In the detection stage, density level is statistically modeled as a significance level controlled by the number and support domain of the points in the dataset, and then a hypothesis test is used to detect the high‐density points. In the removal stage, the Delaunay triangulation network is used to construct clusters and support domains for the identified high‐density points, and then the high‐density points and their support domains are removed from the dataset. The detection and removal operation are iteratively implemented until no high‐density points can be detected. Experiments and comparisons show that the proposed method, on the one hand, outperforms four state‐of‐the‐art methods for detecting clusters of complex shapes and diverse densities, and on the other hand, no user‐specified parameters are required. In addition, the support domains of clusters are very useful for spatial analysis.
Bortezomib for chronic relapsing thrombotic thrombocytopenic purpura: a case report
Authors: Yates Sean , Matevosyan Karen , Rutherford Cynthia , Shen Yu‐Min , Sarode Ravi 
Published: March 2014

BackgroundAcquired thrombotic thrombocytopenic purpura (TTP) is an autoimmune disorder characterized by a severe deficiency of ADAMTS13 activity. Although therapeutic plasma exchange (PLEX) is the standard of care, 30% to 50% patients develop exacerbation or relapse, requiring immunomodulatory agents. Of these agents, glucocorticoids, rituximab, and cyclosporine A are the most frequently used.Case ReportWe report a case of chronic relapsing TTP in a patient who had eight relapses over a 14‐year period. After her seventh relapse, the patient demonstrated only partial response to glucocorticoids, two courses of rituximab, and cyclophosphamide. The eighth relapse occurred 58 days after her last PLEX and subsequent to this she received a course of bortezomib (Velcade, Millennium Pharmaceuticals, Inc.). After treatment with bortezomib the patient demonstrated a complete response with a progressive increase in ADAMTS13 activity from less than 5% to 22% accompanied by undetectable inhibitor, and she has remained PLEX free for more than 169 days.ConclusionBortezomib may serve as an adjunct treatment in patients with acquired TTP who exhibit an incomplete response or are refractory to conventional management.
Optimized feline vitrectomy technique for therapeutic stem cell delivery to the inner retina
Authors: Jayaram Hari , Becker Silke , Eastlake Karen , Jones Megan F. , Charteris David G. , Limb G. Astrid 
Published: March 2014

AbstractObjectiveTo describe an optimized surgical technique for feline vitrectomy which reduces bleeding and aids posterior gel clearance in order to facilitate stem cell delivery to the inner retina using cellular scaffolds.ProceduresThree‐port pars plana vitrectomies were performed in six‐specific pathogen‐free domestic cats using an optimized surgical technique to improve access and minimize severe intraoperative bleeding.ResultsThe surgical procedure was successfully completed in all six animals. Lens sparing vitrectomy resulted in peripheral lens touch in one of three animals but without cataract formation. Transient bleeding from sclerotomies, which was readily controlled, was seen in two of the six animals. No cases of vitreous hemorrhage, severe postoperative inflammation, retinal detachment, or endophthalmitis were observed during postoperative follow‐up.ConclusionsThree‐port pars plana vitrectomy can be performed successfully in the cat in a safe and controlled manner when the appropriate precautions are taken to minimize the risk of developing intraoperative hemorrhage. This technique may facilitate the use of feline models of inner retinal degeneration for the development of stem cell transplantation techniques using cellular scaffolds.
Typification of the plant names described by Nedeljko Košanin from the Balkan Peninsula
Authors: Vukojicic Snezana , Jakovljevic Ksenija , Djurovic Sanja , Kuzmanovic Nevena , Jankovic Ivana , Stevanovic Vladimir 
Published: March 2014

Nedeljko Košanin was one of the most important Serbian botanists from the beginning of the 20th Century. He dedicated most of his life to investigate the flora of Southern Serbia as well as Albania and the Former Yugoslav Republic of Macedonia. Since he was working at the Institute of Botany and Botanical Garden in Belgrade, the majority of his collection is deposited in BEOU. While describing new taxa, in most of his publications he did not indicate the holotype. The present study discusses the lectotypification of 7 names published by Košanin alone, or with his contemporaries.
Higher Education Embracing Students’ Health Protection Technologies: A Practical Evaluation
Authors: Танеева Екатерина , Taneeva Ekaterina , Троицкая Нина , Troitskaya Nina 
Published: March 2014

Personal health is a universally recognized asset leading to higher life satisfaction and life expectancy.
According to the data provided by the World Health Organization, 20% of personal health is determined
by hereditary biological factors, 20% is accounted for by environmental variables, a minor fraction of 10%
depends on the healthcare system, and a major of 50% of personal health is related to individual lifestyles.
With over a third of Russia’s population neglect health issues, top national priority is given to new initiatives
within the framework of the National Project ‘Health’, as well as other state projects designed to promote
healthy lifestyles among all the age groups.
Adaptive Logic as Applied to Educational and Production Technologies
Authors: Сучилин Владимир , Suchilin Vladimir , Архипова Татьяна , Arkhipova Tatyana 
Published: March 2014

The article discusses the elements of educational continuity and production technology related scientific outlook
on these processes in the past and the modern world. Noted that Conceptual innovations in science and
technology contribute to the emergence of the scientific and technical world of active development of modern
analytical technologies of a new type. Relying on new trends in science, engineering and technology is considered
one of them, the most relevant in the present — nanotechnology. It is noted that in the scientific and
technical world appear and actively develop overtime analysis of a new type of technology, the theory of which
is based on the provisions of the adaptive logic. Touched on the importance of using artificial neural networks
to solve applied problems. The importance of such technologies highlighted by the fact that they will contribute
to the solution of ill-posed problems that often arise in practical human activity. The practical results of the
adaptation of technical and technological solutions to the conditions of their functioning. Introduces the algorithm
of group technology manufacturing processes. It is noted that modern educational technologies based on
dichotomous methods and adaptive learning systems. Stressed the importance of the workplace and in various
industrial applications of intelligent neural network controller that can detect potentially dangerous situations
to notify people about them and take adequate and, most importantly, timely.
How to Develop Multiform Geometric Vision in Schoolchildren
Authors: Виситаева  , Visitaeva Maret 
Published: March 2014

Different interpretations for the notion of «section» are presented followed by classification of tasks, aimed at developing ability to operate with
different configurations of geometric sections by types thereof (propaedeutical tasks on geometric sections; tasks on recognizing geometric figures by
their geometric sections configurations; tasks on recognizing geometric sections by configurations of a given geometric figure; tasks on constructing
geometric figure by a set of its geometric sections; tasks on constructing geometric sections by configuration of a given geometric figure, mixed tasks).
Classifying Techniques of Educational Activities
Authors: Бершадский  , Bershadskiy Mikhail 
Published: March 2014

The paper considers issues related to classifying techniques of educational activities. The lack of logically consistent overall classification of educational
activities is emphasized. To develop such classification it is proposed to identify explicit and implicit attributes of the «technique» notion. One of the
explicit attributes is a set of conditions necessary for the technique to be designed and implemented. Implicit attributes depend on psychological and
pedagogical theories applied for technique designing in the course of pedagogical phenomena modeling. The author identifies three groups of explicit
attributes, namely, educational goals; educational contents; contingent of learners. Possible variations of the said attributes are described. Also described
are various taxonomies of goals, kinds of educational contents and types of learners by stage of education and intellectual development of learners. To
facilitate classification of educational activities techniques the orthogonal three-dimensional model is constructed to serve as a morphological matrix,
describing a set of technologies, necessary to implementing the State educational standards.
Familial Predisposition for Salivary Gland Cancer in Finland
Authors: Aro Katri , Klockars Tuomas , Leivo llmo , Mäkitie Antti 
Published: March 2014

Background Salivary gland cancer (SGC) accounts for 3–5% of head and neck malignancies, and register-based studies estimate the familial proportion to be 0.15%. Objective We studied familial predisposition for SGC in the genetically distinct Finnish population. Patients and Methods We sent a patient questionnaire to 161 Finnish SGC patients, 86 of whom responded. Results A total of 76% of the patients reported having one or more relatives with cancer, 30% two or more, and 9% three or more but only one patient reported having a relative with SGC. Tracing the birthplaces of the SGC patients’ grandparents showed no regional clustering suggestive of a founder effect. Conclusions Lack of familial SGC patients and the absence of a founder effect strongly suggest that familial predisposition for SGC is insignificant in the Finnish population. Various histological subtypes and the rarity of these neoplasms make it impossible to draw conclusions about site-specific association between SGC and other malignancies.
Jeśmanowicz’ Conjecture with Congruence Relations. II
Authors: Fujita Yasutsugu , Miyazaki Takafumi 
Published: March 2014

AbstractLet a, b, and c be primitive Pythagorean numbers such that a2 + b2 = c2 with b even. In this paper, we show that if b0 ≡ ∊(mod a) with ε ∊ {±1} for certain positive divisors b0 of b, then the Diophantine equation ax + by = cz has only the positive solution (x, y, z) = (2, 2, 2).
Cue‐Based Processing Capacity, Cognitive Load and the Completion of Simulated Short‐Duration Vigilance Tasks in Power Transmission Control
Authors: Small Aaron J. , Wiggins Mark W. , Loveday Thomas 
Published: March 2014

SummaryThe interaction between human operators and advanced technology systems has become increasingly complex, particularly with the introduction of automated and semi‐automated systems. This complexity is evident in increasing demands for vigilance in what might be regarded as low stimulus environments. Using resource theory as an explanation of the reduction in sustained attention to a task, the present study sought to examine the relationship between cue utilisation and sustained attention in the context of simulated power system control. The participants comprised power system operators from an Australian power transmission organisation, together with university engineering students. Controlling for experience, the results identified a relationship between different levels of cue utilisation and response latency over successive trials on a short vigilance task, consistent with resource theory. At an applied level, the results have implications for the selection and assessment for operators in environments where sustained attention is a necessary requirement. Copyright © 2014 John Wiley & Sons, Ltd.
Size controlling of monodisperse carboxymethyl cellulose microparticles via a microfluidic process
Authors: Ke Yu , Liu GuoSheng , Guo Tianhui , Zhang Yi , Li Chenghua , Xue Wei , Wu Gang , Wang Jiahui , Du Chang 
Published: March 2014

ABSTRACTMonodisperse carboxymethyl cellulose containing phenolic groups (CMC‐Ph) microdroplets with a radius of 100–400 μm and a coefficient of variation below 3% were produced in a coflowing microfluidic device. The CMC‐Ph solution containing horseradish peroxidase was used as the disperse phase and liquid paraffin containing H2O2 and lecithin as the continuous phase. The size of microdroplets decreased with the decreasing diameter of the inner channel and concentration of the disperse phase. When using a 0.04% CMC‐Ph solution and the device with the inner diameter of 160 μm, the size of the microdroplets can be further controlled by the flow rates of both the continuous phase and disperse phase following exponential models. The volume of the microdroplet was not inversely proportional to the flow‐rate ratio of the continuous phase to the disperse phase. There was a weak dependence of the volume on the flow of the continuous phase. The monodisperse microparticles possessed potential application for sensor, drug delivery system, cell encapsulation, catalysis, and imaging. © 2014 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2014, 131, 40663.
Epoxy compositions cured with aluminosilsesquioxanes: Thermomechanical properties
Authors: Chmielewska Danuta , Sterzyński Tomasz , Dudziec Beata 
Published: March 2014

ABSTRACTThe aim of this study was to verify the influence of bis(heptaphenylaluminosilsesquioxane) (AlPOSS), used as a curing agent, on the thermomechanical properties of epoxy resin. Moreover, various curing conditions were taken into account. Epoxy casts were prepared from epoxy resin based on bisphenol A cured with different amounts of bis(heptaphenylaluminosilsesquioxane). The thermomechanical properties were investigated during dynamical mechanical thermal analysis (DMTA) in two cycles of heating. The storage modulus G′ of the epoxy casts was found to be higher in comparison to the reference epoxy sample and significantly dependent on the POSS content. A correlation between the glass transition temperatures (Tg), the curing conditions and the amount of curing agents were closely related. The occurrence of the crosslinking process in epoxy matrix was proved by the FTIR spectroscopy. The structure of the epoxy casts was investigated using scanning electron microscopy (SEM). © 2014 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2014, 131, 40672.
ChemInform Abstract: New Roles for Icosahedral Clusters in Intermetallic Phases: Micelle‐Like Segregation of Ca—Cd and Cu—Cd Interactions in Ca10Cd27Cu2.
Authors: Hadler Amelia B. , Harris Nicholas A. , Fredrickson Daniel C. 
Published: March 2014

AbstractThe new intermetallic title compound is synthesized from a stoichiometric mixture of the elements (Ta tube, 1100 °C, 48 h, followed by annealing at 500 °C for 100 h).
ChemInform Abstract: Ba3M2[B3O6(OH)]2 [B4O7(OH)2] (M: Al, Ga): Two Novel UV Nonlinear Optical Metal Borates Containing Two Types of Oxoboron Clusters.
Authors: Cheng Lin , Wei Qi , Wu Han‐Qing , Zhou Liu‐Jiang , Yang Guo‐Yu 
Published: March 2014

AbstractThe title compounds are hydrothermally synthesized from mixtures of H3BO3, Al(O‐iPr)3 or Ga(O‐iPr)3, Ba(OH)2, and H2O (autoclave, 220 °C, 10 d, 75 and 58% yield for the Al‐ and Ga compound, respectively).
ChemInform Abstract: B2S2O9: A Boron Sulfate with Phyllosilicate Topology.
Authors: Logemann Christian , Wickleder Mathias S. 
Published: March 2014

AbstractThe title compound with a structure analogous to a typical layer‐type silicate is synthesized from a mixture of B(OH)3 and HSO3Cl (glass tube, 200 °C, 24 h).
ChemInform Abstract: Iodobenzene‐Catalyzed Oxabicyclo[3.2.1]octane and [4.2.1]Nonane Synthesis via Cascade C—O/C—C Formation.
Authors: Ngatimin Marsewi , Frey Raphael , Levens Alison , Nakano Yuji , Kowalczyk Marcin , Konstas Kristina , Hutt Oliver E. , Lupton David W. 
Published: March 2014

AbstractA concise method to oxabicyclo[3.2.1]octanes and [4.2.1]nonanes is developed via 1,2‐olefin functionalization cascade using two distinct nucleophiles.
ChemInform Abstract: Catalytic Asymmetric Bromolactonization Reactions Using (DHQD)2PHAL‐Benzoic Acid Combinations.
Authors: Armstrong Alan , Braddock D. Christopher , Jones Alexander X. , Clark Stacy 
Published: March 2014

AbstractThe use of benzoic acid as the additive for the bromolactonization of various carboxylic acids in the presence of catalytic amounts of (DHQD)2‐PHAL affords the corresponding lactones with improved enantioselectivity.
ChemInform Abstract: α‐Aminoamides as Ligands in Goldberg Amidations.
Authors: Mitra Aurpon W. , Hansen Marvin M. , Laurila Michael E. , Kolis Stanley P. , Martinelli Joseph R. 
Published: March 2014

Abstractα‐Aminoamides are shown to be useful as ligands in Goldberg amidations.
ChemInform Abstract: Expedient Synthesis of Novel β‐Ketoesters from the Mizoroki—Heck Coupling of Ethyl 3‐Ethoxyacrylate with Aryl and Pyridyl Halides.
Authors: Kohrt Jeffrey T. , Conn Ed , Maguire Robert , Wright Stephen W. , Singer Robert 
Published: March 2014

AbstractA mild and generally applicable two‐step synthesis of aryl‐ and heteroaryl‐substituted β‐ketoesters via Mizoroki—Heck reaction and subsequent hydrolysis is presented.
ChemInform Abstract: AlCl3‐Promoted [3 + 2] Annulation of cis‐2,3‐Disubstituted Cyclopropane 1,1‐Diesters with Isothiocyanates: Stereoselective Synthesis of Densely Substituted 2‐Iminodihydrothiophenes.
Authors: Sun Yongxian , Yang Gaosheng , Chai Zhuo , Mu Xiaolong , Chai Jun 
Published: March 2014

AbstractTitle compounds (I) are found to be significantly more reactive than their corresponding trans‐isomers in the annulation reaction with isothiocyanates (II).
ChemInform Abstract: Cycloisomerization of 2‐Alkynylanilines to Indoles Catalyzed by Carbon‐Supported Gold Nanoparticles and Subsequent Homocoupling to 3,3′‐Biindoles.
Authors: Perea‐Buceta Jesus E. , Wirtanen Tom , Laukkanen Otto‐Ville , Maekelae Mikko K. , Nieger Martin , Melchionna Michele , Huittinen Nina , Lopez‐Sanchez Jose A. , Helaja Juho 
Published: March 2014

AbstractThe cycloisomerization of 2‐alkynyl substituted anilines (I) is studied using a heterogeneous gold on carbon catalysts.
ChemInform Abstract: Rhenium‐Catalyzed Synthesis of 3‐Imino‐1‐isoindolinones by C—H Bond Activation: Application to the Synthesis of Polyimide Derivatives.
Authors: Sueki Shunsuke , Guo Yuanfang , Kanai Motomu , Kuninobu Yoichiro 
Published: March 2014

AbstractA new method to synthesize the title compounds from aromatic imidates and isocyanates is presented.
ChemInform Abstract: Copper‐Mediated Selective C—H Activation and Cross‐Dehydrogenative C—N Coupling of 2′‐Aminoacetophenones.
Authors: Ilangovan Andivelu , Satish Gandhesiri 
Published: March 2014

AbstractAn efficient copper(II)‐catalyzed cross‐dehydrogenative intramolecular C—N coupling of an acetyl group and an amine furnishes isatins.
ChemInform Abstract: An Organocatalytic Highly Efficient Approach to the Direct Synthesis of Substituted Carbazoles in Water.
Authors: Jaiswal Pradeep Kumar , Biswas Soumen , Singh Shivendra , Samanta Sampak 
Published: March 2014

AbstractA simple, green synthesis of title compounds (III) and (VI) is achieved via a one‐pot domino Michael—Henry/aromatization reaction of indolyl acetates with β‐nitroolefins (II) under air using DABCO as an organocatalyst.
ChemInform Abstract: Expeditious Synthesis of Bicyclic Pyrrolidine/Pyrrolizidine/Thiazolidine Grafted Macrocycles Through Intramolecular 1,3‐Dipolar Cycloaddition of Azomethine Ylides.
Authors: Purushothaman S. , Prasanna R. , Raghunathan R. 
Published: March 2014

AbstractAlkenyl aldehydes (I) react with secondary aminoacids to generate azomethine ylide intermediates, which undergo intramolecular 1,3‐dipolar cycloaddition to give macrocyclic products.
ChemInform Abstract: Synthesis of Novel Biaryl Derivatives of Sesamol (5‐Benzodioxolol) and Evaluation of Their Antioxidant Activity Against DPPH Radical.
Authors: Rodriguez Sergio A. , Nazareno Monica A. , Baumgartner Maria T. 
Published: March 2014

AbstractThe photoinduced reaction of sesamol (I) with aryl halides (II) leads to biaryl coupling products (III), whilst the reaction with chloride (VII) gives rise to O‐arylated derivative (VIII).
ChemInform Abstract: Isothiourea‐Mediated One‐Pot Synthesis of Functionalized Pyridines.
Authors: Stark Daniel G. , Morrill Louis C. , Yeh Pei‐Pei , Slawin Alexandra M. Z. , O'Riordan Timothy J. C. , Smith Andrew D. 
Published: March 2014

AbstractThe reaction of a range of α,β‐unsaturated ketimines with (phenylthio)acetic acid in the presence of an isothiourea catalyst is developed to yield 2,4,6‐trisubstituted pyridines.
ChemInform Abstract: Alkylation of 2‐Methylquinoline with Alcohols under Additive‐Free Conditions by Al2O3‐Supported Pt Catalyst.
Authors: Chaudhari Chandan , Siddiki S. M. A. Hakim , Shimizu Ken‐ichi 
Published: March 2014

AbstractMoreover, the catalyst can be reused at least four times without significant loss of activity.
ChemInform Abstract: Synthesis of Isoquinolines via Rh(III)‐Catalyzed C—H Activation Using Hydrazone as a New Oxidizing Directing Group.
Authors: Chuang Sheng‐Chieh , Gandeepan Parthasarathy , Cheng Chien‐Hong 
Published: March 2014

AbstractAn efficient method for the synthesis of highly substituted isoquinolines by a Rh(III)‐catalyzed hydrazone directed ortho C—H bond activation and annulation without an external oxidant is described.
ChemInform Abstract: Synthesis of Fused Pyridines in the Presence of Thiamine Hydrochloride as an Efficient and Reusable Catalyst in Aqueous Conditions.
Authors: Siddiqui I. R. , Rai Pragati , Srivastava Anushree , Srivastava Arjita , Srivastava Anjali 
Published: March 2014

AbstractThe synthesis of fused pyridines (IV) and (VI) involves addition on an activated olefinic bond, generated in situ by Knoevenagel condensation between an aromatic aldehyde and an active methylene compound.The Michael product on subsequent cyclocondensation affords the target compound in high yield.
ChemInform Abstract: Microwave‐Assisted Expeditious and Efficient Synthesis of Cyclopentene Ring‐Fused Tetrahydroquinoline Derivatives Using Three‐Component Povarov Reaction.
Authors: Kulkarni Abhijit R. , Thakur Ganesh A. 
Published: March 2014

AbstractAn efficient microwave‐assisted synthesis of cyclopentene ring‐fused tetrahydroquinolines using a three‐component Povarov reaction is reported.
ChemInform Abstract: Kinetic Resolution of Unsaturated Amides in a Chlorocyclization Reaction: Concomitant Enantiomer Differentiation and Face Selective Alkene Chlorination by a Single Catalyst.
Authors: Jaganathan Arvind , Staples Richard J. , Borhan Babak 
Published: March 2014

AbstractKinetic resolution and chlorofunctionalization are mediated by the same catalyst and proceed in one step.
ChemInform Abstract: Asymmetric Three‐Component Domino Reaction: An Original Access to Chiral Nonracemic 1,3‐Thiazin‐2‐ones.
Authors: Peudru Flavie , Le Cavellier Fabien , Lohier Jean‐Francois , Gulea Mihaela , Reboul Vincent 
Published: March 2014

AbstractA new asymmetric three‐component domino process, based on a diastereoselective hetero‐Diels—Alder reaction, involving an aldehyde, an alkene, and a chiral thiocarbamate is developed.