bluuebunny/crossref_metadata_2025_split huggingface dataset:
Modeling and simulation on the spreading dynamics of public opinion information in temporal group networks
Authors: Wang Jiakun , Mu Linru , Chun Liu , Guo Xiaotong 
Published: July 2024

Abstract

Under the new media environment, the constantly emerging social platforms further expand the channels for the propagation of public opinion. In view of this, modeling the spreading dynamics of public opinion in group networks is of great significance for understanding its spreading law and improving the governance system of cyberspace. Through analyzing the changes of group networks topology and the spreading rules of public opinion, the spreading model of public opinion in temporal group networks was proposed by coupling the two dynamic processes, and the spreading thresholds of public opinion in static and temporal group networks were derived respectively. Then, the spreading characteristics of public opinion under different network topology, as well as the influence of important parameters on public opinion spreading process were discussed with the help of simulation experiments. The research results indicated that the propagation of public opinion in static and temporal group networks exhibits both similar trends and differentiated characteristics: compared with Spreader, the propagation of public opinion in temporal group networks is more sensitive to Ignorant’s behavior; the active probability of both groups and netizens affect the spreading process of public opinion, but netizens’ active probability affect more. Based on the relevant results, this paper proposed a series of countermeasures such as, grading social platforms, strengthening relationship management between them and introducing time management systems, so as to promote the formation of a good network ecosystem and the modernization of the national governance system.
The challenging management of a Cotard´s Syndrome: a case report
Authors: Sousa Bárbara Castro , de Sá Zoé Correia , Ramos Joana 
Published: July 2024

Abstract

Psychiatric disorders exhibit diverse presentations, giving rise to a plethora of therapeutic approaches, wherein the trajectory and treatment response can serve as predictive indicators of recuperation. Catatonia, an autonomous syndrome, can manifest across various mental and organic contexts, boasting a worldwide prevalence impact of 9.2%. Even rarer is the convergence of catatonia with nihilistic delusions – a fusion exemplified by Cotard's Syndrome – a rarity observed among patients. Thus, drawing from the portrayal of a unique case involving an inaugural psychotic episode characterized by treatment resistance, the author emphasizes the importance of successive adjustments in antipsychotic therapy, fostering a more efficient approach to treating patients grappling with refractory psychotic conditions.
Patient with advanced aggressive B2 thymoma achieved positive outcomes post CAP-Endostar combination therapy
Authors: Zhang Min , Zhang Jingjing , Zhao Kelei , Yuan Xiaohan , Zhang Jinghang , Liu Yanting , Lu Ping 
Published: July 2024

Abstract

This case report features a patient with an invasive thymoma. The patient presented with an anterior mediastinal mass that invaded the left brachiocephalic trunk vein, resulting in the formation of a carcinoma thrombus in the right atrium-superior vena cava-left brachiocephalic trunk vein and left internal jugular vein (Masaoka stage IV). No indication for surgery was assessed by surgical consultation. Following 6 cycles of chemotherapy and chest radiotherapy, the patient achieved a significant improvement in efficacy. After a follow-up of 40 months, the patient remained well, without local recurrence or distal metastasis, and maintained a partial response (PR) .
Learning Superior Energy Management from Electric Vehicle Data
Authors: He Hongwen , Wang Yong , Wu Jingda , Wei Zhongbao , Sun Fengchun 
Published: July 2024

Abstract

Despite the promising potential of energy management technologies in optimizing electric vehicle (EV) performance and fostering global energy sustainability, the extensive research conducted over the past decade has yet to translate into practical applications. This discrepancy arises primarily from the reliance of existing methodologies on simulation-based development paradigms, leading to a significant disparity between simulated results and real-world efficacy. Herein, we present a pioneering real-world data-driven energy management strategies (EMS) approach that utilizes an innovative offline reinforcement learning (ORL) framework. This paradigm enables EMS to learn from diverse real-world data, obviating the need for explicit rule design or high-fidelity simulators, and allowing for seamless application of the proposed method to any existing EMS. Moreover, it continuously enhances performance even after deployment in actual energy management systems. We evaluate the proposed ORL method on fuel cell EVs, training the ORL agent to optimize energy consumption and system degradation. The EV monitoring and management platform in China provides real-world data for validating our methodology. The results demonstrate that ORL consistently learns superior EMS in various conditions. With increasing data availability, its performance improves significantly, from 88\% to 98.6\% relative to theoretical optimality after two data updates. After training with more than 60 million kilometers of data, the ORL agent can learn a general EMS that adapts to unseen and corner-case conditions. These results highlight the effectiveness of integrating the data-driven method with established EMS techniques to enhance performance and underline its potential to utilize large-scale data to improve vehicle energy efficiency and longevity.
Outputs from a model of co-research with older care-experienced people in Sweden to advance eldercare services
Authors: Wallcook Sarah , Dohrn Ing-Mari , Dahlkvist Ulla , Domeij Yvonne , Green Kerstin , Isaksson Gigi , Goliath Ida 
Published: July 2024

Abstract

Background: Within the contemporary policy turn towards co-production and co-research in Sweden, older people, practitioners and researchers alike have expressed uncertainty about how to undertake co-research. Moreover, scepticism persists about the merits and contributions of co-research and co-production to research and service development. In this paper, we aim to describe a co-research model developed with older care-experienced lay co-researchers and explore the utility of our model’s outcomes to social care research and practice.
Method: In a Participatory Action Research project we established a team of three co-researchers by professional experience and eight lay co-researchers by lived experience who were over age 75. Our team undertook a complete study cycle from inception and funding through to knowledge exchange and dissemination. Our process lasted one year and comprised three phases: the group alone establishing collective knowledge, testing knowledge in peer interviews with acquaintances, exchanging knowledge in events with multi-sector actors. We generated and analysed data concurrently in fortnightly workshops and round-table meetings using procedures inspired by framework analysis to produce themes illustrated by vignettes.
Findings: We highlight our co-research model’s utility to social research, policy and practice under three themes. Expressly, how our approach 1) reaches and engages older people who are isolated at home, 2) generates out-of-the box thinking and innovative solutions for service development and research, 3) recognizes and benefits from older people’s authentic experience and knowledge. We critically reflect upon these three themes and the conditions that lead towards or away from the adoption of key co-creation principles.
Conclusions: Public services and research and development units working in the interests of older people can take inspiration from our co-research model when seeking to meet the challenges brought by new reforms towards closer community involvement. Despite messiness in the process, integrating and embedding principled co-research and co-production can bring clarity and structure to the issues that matter most to older people, and draw organisations closer to the communities they serve.
Efficacy of Lumbar Support on Pain, Disability, and Motor Control in Women with Postpartum Pelvic Girdle Pain: a Three-armed Randomized Controlled Trial
Authors: Jafarian Fahimeh-Sadat , Jafari-Harandi Mahmonir , Yeowell Gillian , Sadeghi-Demneh Ebrahim 
Published: July 2024

Abstract

Background
Pregnancy-related posterior pelvic girdle pain (PPGP) is a common cause of back pain and disability in the postpartum period. The objective of this study was to investigate the efficacy of orthotic support on pain, disability, and motor control in women with pregnancy-related PPGP.
Methods
Eighty-four women with a clinical diagnosis of pregnancy-related PPGP participated in this randomized controlled trial (RCT). Participants were randomly allocated into three groups (with a ratio of 1:1:1): the pelvic support group, the lumbar support group, and the control group (patient-education leaflet). Pain severity, disability, effort during the active straight leg raising test (ASLR), maximum isometric muscle force (hip flexion and trunk rotation), and joint position reproduction (JPR) of hip abduction were assessed as study outcomes. These variables were measured at four time points—before the intervention, immediately after the intervention, at the 4-week follow-up (at this time, the intervention period was terminated), and at the 5-week follow-up (one week after discontinuing the interventions)—to evaluate the possible effects of wearing support. Repeated-measures multivariate analysis of variance (MANOVA) was applied to determine the statistical significance between groups. Bonferroni post-hoc correction was used to identify significant differences between groups at different study time points.
Results
There was a significant interaction effect for group×time for the study outcomes, including pain severity, disability, effort during the ASLR, and maximum isometric muscle force between groups (p < 0.001), except JPR of hip abduction (p = 0.13). There were statistically significant differences in post hoc comparisons for pain intensity and effort during the ASLR in lumbar support versus control condition and for maximum isometric muscle force in orthotic interventions versus control conditions immediately after the intervention (P < 0.008). Post hoc tests demonstrated statistically significant differences in orthotic interventions versus control conditions after 4-week and 5-week follow-ups (P < 0.008). None of the interventions significantly changed the JPR of hip abduction compared to the control group (p > 0.008).
Conclusions
For women with pregnancy-related PPGP, both lumbar and pelvic supports were beneficial for decreasing pain and disability symptoms. Lumbar support showed better results for managing PPGP than pelvic support.
Clinical Trial registration: Iranian Registry of Clinical Trials IRCT20150210021034N11. Date of registration: April 31, 2021. Available at: https://irct.behdasht.gov.ir/trial/70670
Spatial Overlap Between Latent Mycobacterium Tuberculosis Infection and Venezuelan Migrants
Authors: Zambonin Fernanda , Júnior Nilson Cavalcante de Souza , Maciel Elvira Maria Godinho de Seixas , Braga Jose Ueleres 
Published: July 2024

Abstract

Background
Migrants are a high-risk group for TB and LTBI due to social determinants of health, such as poor living conditions and limited healthcare access. Since 2015, Roraima has faced significant Venezuelan migration, necessitating enhanced health surveillance efforts. Understanding the geographical conditions and their impact on migrants' health is crucial. This study aimed to evaluate the spatial overlap of TB and LTBI incidence in Boa Vista, Roraima, and its correlation with the Venezuelan migrant population from 2018 to 2022.
Methods
An ecological study was carried out, using data from the Tuberculosis Notifiable Diseases Information System and the Information System for LTBI. The study population consisted of TB-notified cases and LTBI living in Boa Vista during the study period. Spatial distribution patterns were assessed with thematic maps and local Getis-Ord statistics to identify hotspots, Kendall's W statistics to assess the TB and LTBI incidence overlap, and the Pearson correlation coefficient to evaluate the relationship between LTBI incidences and the proportion of Venezuelan migrants.
Results
Typical heterogeneous distributions of both LTBI and TB were observed; TB hotspots were present in the western and southern zones, and LTBI in the central and southern zones. The overlapping of the incidence of LTBI and TB pointed to significant agreement between the average annual incidence rates of LTBI and TB. There was a significant correlation between the LTBI incidence rate and the proportion of Venezuelan migrants.
Conclusion
The identification of LTBI risk areas could support health surveillance actions and targeted control and prevention and measures, especially for vulnerable populations.
HA: An influential node identification method based on hub-triggered neighborhood decomposition and asymmetric order-by-order recurrence model
Authors: Zhao Min , Ye JunHan , li JiaYun 
Published: July 2024

Abstract

In recent years, the proliferation of major power network security incidents triggered by malicious attacks has drawn widespread attention to influential nodes in power networks. Among the existing influential node identification algorithms, the global algorithms are too complex and not suitable for large-scale networks. The local algorithms are too simply to ignore the differentiated features of the same node in different information dissemination processes. To overcome these shortcomings, this paper proposes a novel influential node identification method based on hub-triggered neighborhood decomposition and asymmetric order-by-order recurrence model. The concepts of network directionalization strategy and hub-triggered neighborhood decomposition are introduced to distinguish the functional differences between nodes in the virus-spreading process. Moreover, this paper proposes the concepts of infected potential and infecting potential, and constructs a calculation model with asymmetric characteristics based on the order-by-order recurrence method to make full use of the information in the connection structure of the adjacent neighborhood. Finally, the influence of the hub node is evaluated by integrating the infected potential and infecting potential of neighbors of multiple orders. Experimental results show that the algorithm proposed in this paper outperforms the other six algorithms in terms of SIR correlation coefficient, imprecision function and algorithm resolution.
Clinical Perinatal Management of High-Risk Fetal Congenital Pulmonary Airway Malformation
Authors: Cai Chun , Tian Miao , Liu Cuifen , Zhang Gang , Li Xiao , Zhou Bin , Sun Yuling , Yu Gang 
Published: July 2024

Abstract

Objectives: To summarize the clinical experience in managing high-risk fetuses with congenital pulmonary airway malformation (CPAM).
Design: A retrospective analysis of integrated management clinical data was conducted for high-risk fetuses with CPAM treated at the Third Affiliated Hospital of Guangzhou Medical University and Guangdong Women and Children Health Hospital from 1st July 2015 to 30th June 2021. Data were collected before, during, and after birth.
Setting: Third Affiliated Hospital of Guangzhou Medical University and Guangdong Women and Children Health Hospital. Patients: A total of 51 patients were included in the study.
Intervention: Prenatal maternal glucocorticoid (GC) treatment was administered in 27 cases.
Measurements and Main Results: Prenatal data showed the first diagnosis at 22.90±2.34 weeks' gestation with a prenatal ultrasound congenital pulmonary airway malformation volume ratio (CVR) value of 3.08±0.91. Lesions were diagnosed in the left lung in 27 cases (52.9%), with microcystic changes present in 12 cases (23.5%). Mediastinal shift was observed in 23 cases (45.1%), with 20 cases (39.2%) exhibiting fetal hydrops. Prenatal maternal glucocorticoid (GC) treatment was administered in 27 cases, with a survival rate of 81.4% in the GC group and 95.8% in the non-GC group, showing no statistical difference (P=0.116). Postnatal data indicated an average gestational age of 37.98±2.63 weeks, with 13.7% of patients having a 5-minute Apgar score of less than 8. Neonatal surgery was performed in 17.6% of patients, all of which were lobectomies. The survival rate for high-risk CPAM infants was 88.2%, with 70.6% showing no respiratory symptoms after birth. The presence of fetal hydrops, microcystic type, and mediastinal shift did not significantly increase the risk of death. Over the 6-year follow-up period, 12 cases (26.7%) developed pectus excavatum.
Conclusions: Managing high-risk congenital cystic adenomatoid malformation (CCAM) fetuses during the perinatal period remains challenging, but the overall prognosis is generally reasonable. Glucocorticoids may have a role in improving the outcome of high-risk CPAM fetuses, although the statistical significance is still uncertain.
An integrated strategy for pathogen surveillance unveiled Xylella fastidiosa ST1 outbreak in hidden agricultural compartments in the Apulia region (Southern Italy)
Authors: Cornara Daniele , Boscia Donato , D’Attoma Giusy , Digiaro Michele , Ligorio Angela , Loconsole Giuliana , Minutillo Serena Anna , Montilon Vito , Palmisano Francesco , Ragone Gianvito , Silletti Maria Rosaria , Verrastro Vincenzo , Zaza Claudio , Saponari Maria 
Published: July 2024

Abstract

Annual surveillance programs for the plant pathogenic bacterium Xylella fastidiosa are implemented in Europe as part of the preventive phytosanitary strategies enforced to face the emergence of the detrimental infections reported in olives in southern Italy. The program includes inspections and sampling of host plants by prioritizing those showing suspicious symptoms or those known to be highly susceptible to different strains and subspecies of the bacterium. In the framework of these programs numerous outbreaks have been unraveled, with several strains and subspecies found to infect a relatively large host range in France, Spain, Portugal and Italy. Here we report the results of an integrated surveillance approach implemented in the Apulia Region (southern Italy), where a conventional survey program on host plants is complemented by monitoring and testing for X. fastidiosa the insect vectors. In the framework of this program, infective spittlebugs were first intercepted in the Xylella-free area of the region, close to one of the most relevant Italian table grape production district. Such findings prompted further investigation to identify the bacterial reservoir in the host plants. Almond and grapevine were found to be the most frequently infected hosts, with infections caused by isolates of X. fastidiosa subspecies fastidiosa ST1. Investigations are ongoing to assess the extent and history of the outbreak, to assess and estimate the potential impacts, and define the best options for its containment.
Mutations of methionine 444 interacting with T1Cu-coordinating amino acids affect the structure and function of multicopper oxidase CopA
Authors: Tang Wenwei , Jin Xiaoyu , Zhang Peiqi , Li Xiaorong , Chen Shichao , Zeng Xinping 
Published: July 2024

Abstract

Manganese is an essential trace element for humans, animals, and plants, but excessive amounts of manganese can cause serious harm to organisms. The biological manganese oxidation process mainly oxidizes Mn(II) through the secretion of unique manganese oxidase by manganese-oxidizing bacteria. The T1 Cu site of multicopper oxidase is the main site for substrate oxidation, and its role is to transfer electrons to TNC, where dioxygen reduction occurs. In this study, methionine (Met) No. 444 interacting with the T1Cu-coordinating amino acid in the multicopper oxidase CopA from Brevibacillus panacihumi MK-8 was mutated to phenylalanine (Phe) and leucine (Leu) by the enzyme. Based on the analysis of enzymatic properties and the structural model, the mutant protein M444F with 4.58 times the catalytic efficiency of the original protein CopA and the mutant protein M444L with 1.67 times the catalytic efficiency of the original protein CopA were obtained. The study showed that the manganese removal rate of the manganese-oxidizing engineered bacterium Rosetta-pET-copAM444L cultured for 7 days was 88.87%, which was 10.77% higher than that of the original engineered bacterium. Overall, this study provides a possibility for the application of genetic engineering in the field of biological manganese removal.
Objective Analysis of Orbital Rim Fracture CT Images Using Curve and Area Measurement
Authors: Lee Myungchul , Yoo Junghwan , Kim Jeenam , Choi Hyungon , Shin Donghyeok , Lee Hasup 
Published: July 2024

Abstract

The orbital bone presents a closed curve, and fracture results in disfigurement. An image analysis procedure was developed to examine before and after corrective surgery. An ellipse and circumscribed contour embodied the closed curve. Three-dimensional (3D) computed tomography (CT) images of were collected from 25 patients. Orbital rim data were generated, and binary images were created to facilitate closed curve analysis. Various indices, including the solidity value (closed curve area/convex hull area) and ellipse distance (discrepancy between the closed curve and the ellipse traversing the curve), were utilized. The ratios of various indices—including the number of vertices, solidity value, and ellipse distance—between the affected and unaffected sides showed postoperative values that were closer to 1, which would indicate perfect symmetry, than the preoperative measurements (P < 0.05). The solidity value increased, while both the ellipse distance and curvature values decreased, reflecting the transformation of bends into smooth contours following reduction surgery (P < 0.05). Significant correlations were observed between 1-solidity, ellipse distance, and curvature using the Pearson correlation test (P < 0.05). This study validated postoperative changes in various indices and established correlations among multiple values, specifically solidity, ellipse distance, and curvature. Employing multiple indices with mutual complements has provided objective information confidently.