bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reducing iodinated contrast volume by manipulating injection pressure during coronary angiography
Authors: Kaye David M. , Stub Dion , Mak Vivian , Doan Tuan , Duffy Stephen J. 
Published: December 2013

ObjectiveTo evaluate the impact of a device‐mediated modification of the injection pressure profile on iodinated contrast volumes during coronary angiography and percutaneous coronary intervention (PCI).BackgroundThe development of iodinated contrast‐induced acute kidney injury (AKI) is associated with significant morbidity and mortality in patients undergoing coronary angiography and intervention, particularly in the setting of ST‐elevation myocardial infarction. Iodinated contrast volume is a recognized risk factor for iodinated contrast‐induced AKI. Mitigation of iodinated contrast loss due to coronary iodinated contrast reflux represents a potential means to reduce iodinated contrast volume.Method and ResultsWe assessed the effectiveness of injection pressure modulation using an iodinated contrast conservation system (CCS), in 21 patients undergoing diagnostic coronary angiography or PCI. System activation was associated with a marked reduction in iodinated contrast injection compared with standard imaging (3.5 ± 1.1 vs. 5.4 ± 1.7 mL, P < 0.001). Paired images were obtained in 59 instances with significantly less iodinated contrast use with CCS use (3.3 ± 1.1 vs. 5.5 ± 1.6 mL, P < 0.001), with comparable image quality in 98% of cases.ConclusionsModulation of iodinated contrast injection pressure provides a novel potential means to reduce iodinated contrast volumes by attenuating inefficient losses due to ostial reflux. Future studies are required to define the ability of the CCS to reduce total iodinated contrast volume and to impact upon the risk of iodinated contrast‐induced AKI. © 2013 Wiley Periodicals, Inc.
Optimization of the Probe Coverage in DNA Biosensors by a One‐Step Coadsorption Procedure
Authors: Doneux Thomas , De Rache Aurore , Triffaux Eléonore , Meunier Anne , Steichen Marc , Buess‐Herman Claudine 
Published: December 2013

AbstractAnalytical performance (selectivity, sensitivity, limit of detection) of a sensor is ultimately connected to the interfacial architecture of the sensing surface that needs to be optimized. Self‐assembly of a mixed monolayer of thiolated probes and diluent onto gold surfaces used in the design of biosensing platforms is nowadays commonly performed by a two‐step immobilization procedure. In this work, the merits of a one‐step coadsorption procedure are emphasized, and it is shown that the ionic strength is a very efficient tool to fine control the surface concentration of the immobilized probe. Probe densities were obtained by alternating current voltammetry or fluorescence measurements depending on the type of labeling of the probes. With unlabeled DNA sequences, chronocoulometric measurements were performed in the presence of dissolved hexaammineruthenium(III) cations. The maximum probe density achievable at high ionic strength by the one‐step coadsorption procedure is limited by steric constraints and depends on the structure of the sequence. Various thiolated DNA sequences (single‐stranded DNA, double‐stranded DNA, linear, hairpin, quadruplex) coadsorbed with a common diluent, 4‐mercaptobutan‐1‐ol, were used to discuss the structural factors affecting the maximum surface densities obtained for the different types of probe. Application of the one‐step coadsorption procedure to the optimization of the analytical performance of a protein aptasensor is illustrated by building a sensor for the detection of thrombin on the basis of the thrombin binding aptamer sequence.
Facile One‐Pot Fabrication of Hollow Porous Silica Nanoparticles
Authors: Abdelaal Haitham Mohammad , Zawrah Mahmoud Farag , Harbrecht Bernd 
Published: December 2013

AbstractA method for the fabrication of hollow silica nanospheres, a facile one‐pot hydrothermal route, is described. Heating of an aqueous solution of water glass and D‐glucose to 180 °C for 24 h affords—as indicated by transmission electron microscopy—a nanospherical composite consisting of a silica shell sheathing a carbonaceous core. Subsequent removal of the carbonaceous interior through oxidation in air produces hollow silica structures. Variation of the concentration of the two jointly dissolved chemicals enables a variation of the thickness of the silica shell. The hollow silica particles were characterized by means of SEM, TEM, XRD, IR spectroscopy, thermogravimetrical analysis (TGA), and sorption measurements.
N‐Doped Graphene Derived from Biomass as a Visible‐Light Photocatalyst for Hydrogen Generation from Water/Methanol Mixtures
Authors: Lavorato Cristina , Primo Ana , Molinari Raffaele , Garcia Hermenegildo 
Published: December 2013

AbstractThere is much current interest in developing graphene‐based materials as photocatalysts, particularly in the field of solar fuels and the photocatalytic generation of hydrogen. Graphene is a versatile material allowing different modification strategies to improve its activity. Thus, in the present manuscript we report that, in contrast to the lack of photocatalytic activity of undoped graphene, nitrogen doping introduces UV‐ and visible‐light activity for hydrogen evolution; the efficiency of the material depends on the preparation conditions. The N‐doped graphene is obtained by pyrolysis under an inert atmosphere of natural chitosan, which is considered a biomass waste, followed by ultrasound exfoliation, without the need of oxidation and reconstitution. The main parameter controlling the residual amount of nitrogen and the resulting photocatalytic activity is the pyrolysis temperature that produces an optimal material when the thermal treatment is carried out at 900 °C. Due to the fact that, in contrast to graphene oxide, N‐doped graphene exhibits an almost “neutral” absorption spectrum, the material exhibits photocatalytic activity upon UV‐ (355 nm) and visible‐light (532 nm) irradiation, and is able to generate hydrogen upon simulated sunlight illumination.
The RNA/DNA‐binding protein PSF relocates to cell membrane and contributes cells' sensitivity to antitumor drug, doxorubicin
Authors: Ren Simei , She Ming , Li Min , Zhou Qi , Liu Rong , Lu Hong , Yang Chunzheng , Xiong Dongsheng 
Published: December 2013

AbstractCell surface proteins play an important role in multidrug resistance (MDR). However, the identification involving chemoresistant features for cell surface proteins is a challenge. To identify potential cell membrane markers in hematologic cancer MDR, we used a cell‐ and antibody‐based strategy of subtractive immunization coupled with cell surface comparative screening of leukemia cell lines from sensitive HL60 and resistant HL60/DOX cells. Fifty one antibodies that recognized the cell surface proteins expressed differently between the two cell lines were generated. One of them, the McAb‐5D12 not only recognizes its antigen but also block its function. Comparative analysis of immunofluorescence, flow cytometry, and mass spectrum analysis validated that the membrane antigen of McAb‐5D12 is a nucleoprotein—polypyrimidine tract binding protein associated splicing factor, PSF. Our results identified that PSF overexpressed on the membrane of sensitive cells compared with resistant cells and its relocation from the nuclear to the cell surface was common in hematological malignancy cell lines and marrow of leukemia patients. Furthermore, we found that cell surface PSF contributed to cell sensitivity by inhibiting cell proliferation. The results represent a novel and potentially useful biomarker for MDR prediction. The strategy enables the correlation of expression levels and functions of cell surface protein with some cell‐drug response traits by using antibodies. © 2013 International Society for Advancement of Cytometry
Evaluation of displacement coefficient method for seismically retrofitted buildings with various ductility capacities
Authors: Dicleli Murat , Durucan Cengizhan 
Published: December 2013

SUMMARYThis research study is aimed at evaluating the accuracy of the displacement coefficient method (DCM) of FEMA 440 and associated nonlinear static procedure (NLSP) for actual buildings with soft story mechanism and various ductility capacities. The DCM and associated NLSP are evaluated using two existing seismically vulnerable buildings with soft story mechanism. The buildings are first retrofitted using a ductile steel‐brace‐link system to represent those with good ductility capacity and then retrofitted with RC squat infill shear panels (SISPs) to represent those with relatively poor ductility capacity. The evaluation of the DCM of FEMA 440 and associated NLSP is then performed by comparing the roof displacements (target displacements), maximum interstory drifts, and maximum plastic hinge rotations of the original and retrofitted buildings obtained from NLSP (at the target displacement level of DCM) with those obtained from nonlinear response history (NRH) analyses for three different seismic performance levels. It is observed that the DCM, and hence, the NLSP fail to accurately predict the NRH analyses results mainly due to uncertainties in the coefficient C1 of the DCM in the short period range, the inability of the DCM to capture the failure of structural members beyond a certain lateral displacement or plastic rotation limit and associated soft story mechanism. Copyright © 2013 John Wiley & Sons, Ltd.
Graphic Recording
Authors: Dean‐Coffey Jara 
Published: December 2013

AbstractThis chapter explores graphic recording, which is a visualization process that captures the themes and ideas emerging from group discussions. This process is well suited for many phases of an evaluation, but is particularly useful in the initial and final stages to help the evaluator and stakeholder group explore context and clarify focus, discuss data collection findings, and determine their implications. The chapter provides information on what the graphic recording process can look like and how it can fit into evaluation practice, particularly the role that graphic recording can play in increasing cultural responsiveness and stakeholder understanding. The chapter concludes with common questions and answers about the graphic recording process. © Wiley Periodicals, Inc., and the American Evaluation Association.
Sm0.5Sr0.5CoO3–Sm0.2Ce0.8O1.9 Composite Oxygen Electrodes for Solid Oxide Electrolysis Cells
Authors: Jiang W. , Lü Z. , Wei B. , Wang Z. H. , Zhu X. B. , Tian Y. T. , Huang X. Q. , Su W. H. 
Published: December 2013

AbstractIn this paper, a series of Sm0.5Sr0.5CoO3–Sm0.2Ce0.8O1.9 (SSC–SDC) composite with different ratios were prepared and characterized as oxygen electrodes for solid oxide electrolysis cells (SOECs). Yttria‐stabilized zirconia (YSZ) was selected as the electrolyte with a SDC barrier layer to avoid detrimental solid state interaction between SSC and YSZ. At 850 °C, the impedance spectra showed that the optimum SDC content in the composite electrode was found to be about 30 wt.%, which showed a much lower area specific resistance of 0.03 Ω cm2. The electrochemical performances of a Ni–YSZ hydrogen electrode supported YSZ membrane SOEC with the SSC–SDC73 oxygen electrode were also measured at 750–850 °C. The hydrogen production rate calculated from the Faraday's law was 327 mL cm–2 h–1 at 850 °C at an electrolysis voltage of 1.3 V with a steam concentration of ∼40%, which indicated that the SSC–SDC73 was a promising oxygen electrode candidate for high temperature electrolysis cells.
MnO2 Supported Pt Nanoparticels with High Electrocatalytic Activity for Oxygen Reduction Reaction
Authors: Wang X. , Yang Z. , Zhang Y. , Jing L. , Zhao Y. , Yan Y. , Sun K. 
Published: December 2013

AbstractWe report the hydrothermal synthesis of manganese dioxide (MnO2) and its application as platinum nanoparticles (PtNPs) support for oxygen reduction reaction (ORR). The prepared MnO2 samples with different hydrothermal reaction time were systematically investigated by X‐ray diffraction (XRD) and scanning electronic microscopy (SEM), conforming that the crystalline structure of samples was transferred from γ phase to β phase, and the morphology was changed from microspheres to nanorods, respectively. The ORR activity of the samples was evaluated by rotating ring‐disk electrode (RRDE) method and the optimized sample was further utilized as PtNPs support to form a new nanocomposite used as ORR catalyst. We show that the 1 wt.%Pt@MnO2 has a promising performance toward the electrochemical catalytical reduction of oxygen, which an overall quasi 4‐electron transfer in ORR, as well as a limiting reduction current of 0.71 mA was achieved. In comparison with commercialized Pt@C and other Pt‐based catalysts, the MnO2 supported PtNP exhibited remarkable mass activity (per unit mass of Pt), as high as 7.07 mA μg–1, in alkaline solution. We demonstrate that the hydrothermal synthesized MnO2 may offer useful applications as reliable, cost‐effective and morphology controllable support for PtNP as efficient ORR catalysts.
Bifunctionalized Allenes, Part XI: Competitive Electrophilic Cyclization and Addition Reactions of 4‐Phosphorylated Allenecarboxylates
Authors: Ivanov Ivaylo K. , Parushev Ivaylo D. , Christov Valerij Ch. 
Published: December 2013

ABSTRACTThe reaction of the 4‐phosphorylated allenecarboxylates with different electrophilic reagents such as sulfuryl chloride, bromine, benzenesulfanyl, and benzeneselanyl chlorides takes place with a 5‐endo‐trig cyclization or 2,3‐addition reaction depending on the kind of the substituents in the phosphoryl group. Treatment of the 4‐(dimethoxyphosphopyl)‐allenoates with electrophiles gives a mixture of 2,5‐dihydro‐1,2‐oxaphospholes and furan‐2(5H)‐ones in the ratio of about 1.7:1 as a result of the neighboring group participation of phosphonate and carboxylate groups in the cyclization. On the other hand, (3E)‐4‐(diphenylphosphoryl)‐alk‐3‐enoates were prepared, in moderate yields, by chemo‐, regio, and stereoselective electrophilic addition to the C2C3‐double bond in the allenoate moiety. A possible mechanism involving cyclization and addition reactions of the 4‐phosphorylated allenecarboxylates was proposed.
Quality‐Related HR Practices, Organizational Ethics, and Positive Work Attitudes: Implications for HRD
Authors: Valentine Sean , Hollingworth David , Francis Clare A. 
Published: December 2013

AbstractExisting research suggests that human resource (HR) practices and corporate ethics, both of which are orchestrated through human resource development (HRD), enhance employees' work attitudes. Consequently, this study examined the degree to which employees' perception of organizational ethics mediates the relationship between their perceptions of quality‐related HR practices and work attitudes. Results obtained from structural equation modeling of data acquired from 187 professionals in a financial services firm showed full mediation. Stronger perceptions of quality‐related HR practices were associated with increased perceptions of organizational ethics, and stronger perceptions of organizational ethics were associated with more positive work attitudes. The results suggest that quality‐based HR practices can be used in companies to advance an ethical context, ultimately yielding more favorable work attitudes.
Potential innovations in separation technology by nature‐inspired membranes: beneath and beyond the Earth's crust
Authors: Jullok Nora 
Published: December 2013

AbstractThe understanding of complex bio‐mechanisms in nature is explored in this perspective as a way to effectively enable scientific advancements in membrane technology. The mechanisms of nature‐inspired technological improvements are first analyzed from macroscale to nanoscale. Separation methods using membranes can be related to natural separation mechanisms such as soil filtration, when the production of groundwater is considered. Innovative nature‐inspired mechanisms are presented, which include ideas in developing new methods for membrane synthesis in order to boost the vast range of applications of membrane separation processes. Future innovative applications discussed in this paper include nanoscale surface patterning, self‐organization, and the control of these processes. Improvements to existing membranes through the resemblance of natural mechanisms are also aimed towards realizing sustainable and cost‐effective systems. © 2013 Society of Chemical Industry
Yield randomness, cost tradeoffs, and diversification in the EOQ model
Authors: Gerchak Yigal , Parlar Mahmut 
Published: December 2013

AbstractExisting production/inventory models with random (variable) yield take the yield distribution as given. This work takes a step towards selecting the optimal yield randomness, jointly with lot sizing decisions. First, we analyze an EOQ model where yield variance and lot size are to be selected simultaneously. Two different cost structures are considered. Secondly, we consider source diversification (‘second sourcing’) as a means of reducing effective yield randomness, and trade its benefits against its costs. Conditions for the superiority of diversification between two sources with distinct yield distributions over a single source are derived. The optimal number of identical sources is also analyzed. Some comments on the congruence of the results with recent JIT practices are provided.
New results on global stabilization for time‐delay nonlinear systems with low‐order and high‐order growth conditions
Authors: Sun Zong‐Yao , Liu Zhen‐Guo , Zhang Xing‐Hui 
Published: December 2013

SummaryThis paper investigates the global stabilization for a class of high‐order time‐delay nonlinear systems. Compared with the existing references, a distinct characteristic of this paper rests in time‐delay entering high‐order, low‐order, and linear growth parts of system nonlinearities. Based on Lyapunov–Krasovskii theorem and necessary improvement of the adding a power integrator method, a continuous global state‐feedback controller is constructed to preserve the equilibrium at the origin and guarantees the global asymptotic stability of the resulting closed‐loop system. Finally, a simple example is provided to demonstrate the validness of the proposed approach. Copyright © 2013 John Wiley & Sons, Ltd.
Data integration using service composition in data service middleware
Authors: Gannouni Sofien , Beraka Mutaz , Mathkour Hassan 
Published: December 2013

ABSTRACTService‐oriented computing has emerged as the state‐of‐the‐art distributed computing model for loosely coupled service‐centric business applications. Specifically, service‐oriented computing techniques allow organizations to compose Web services. Indeed, the organizational capacity to compose Web services has received much interest, particularly with respect to supporting business‐to‐business or enterprise application integration. In this paper, we present a system that proposes to adopt service composition as a new approach to integrate data from various data sources. We specify the business process description language as well as the service composition engine that supports the proposed language. We also present different strategies for executing a composite data service call. Copyright © 2013 John Wiley & Sons, Ltd.
Data integrity verification scheme with designated verifiers for dynamic outsourced databases
Authors: Wang Xiaoming , Lin Yanchun , Yao Guoxiang 
Published: December 2013

ABSTRACTIn order to verify the integrity of the query results in outsourced database model, we first present a new authenticated data structure by combining skip lists with polynomial functions and accumulators and then construct a data integrity verification scheme for range query. Our scheme can verify the integrity of the query results with constant time verification and constant size proof and support dynamic maintenance with constant computational cost. Compared with that of previous schemes, the communication cost in our scheme is independent of the size of the authenticated dataset and is lower. When dataset size gets larger enough, our scheme outperforms previous schemes in terms of the computational cost and verification cost. In addition, we introduce the designated verifier idea into our scheme, so our scheme achieves the result that none but subscribers can verify the integrity of the query results and then meets the practical demands such as the payment service. The proof of security and analysis of experiment performance show that our scheme is secure and efficient for larger outsourced databases. Copyright © 2013 John Wiley & Sons, Ltd.
XML development with plug‐ins as a service
Authors: Karus S. 
Published: December 2013

SUMMARYExtensible Markup Language (XML) has quickly become a mainstream language in software development. Not only is it used for message and document interchange, it is also used to define application logic and interfaces. However, modern general purpose integrated development environments have rather limited support for XML development. The wide variety of XML‐based languages makes it a challenge to build tools for comprehensive support of XML development. In this paper, we present extensions to a library exposed as an add‐in for Microsoft Visual Studio and a command line tool to improve the development experience by providing access to subscribable service‐based pluggable helper tools. The architecture of the solution allows easier publishing and deployment of the tools, minimising the exposure of development data to third parties and providing service providers with much needed tool usage and development process data. The tools offer developers new means to check their files against good and bad practices, automatically fix errors in XML or improve the files’ conformance with development guidelines, current state of project with other projects, or run service queries to estimate their projects future progress. Copyright © 2013 John Wiley & Sons, Ltd.
A venues‐aware message routing scheme for delay‐tolerant networks
Authors: Niu Jianwei , Liu Mingzhu , Liu Yazhi , Shu Lei , Wu Dapeng 
Published: December 2013

AbstractWith their proliferation and increasing capabilities, mobile devices with local wireless interfaces can be organized into delay‐tolerant networks (DTNs) that exploit communication opportunities arising out of the movement of their users. As the mobile devices are usually carried by people, these DTNs can also be viewed as social networks. Unfortunately, most existing routing algorithms for DTNs rely on relatively simple mobility models that rarely consider these social network characteristics, and therefore, the mobility models in these algorithms cannot accurately describe users’ real mobility traces. In this paper, we propose two predict and spread (PreS) message routing algorithms for DTNs. We employ an adapted Markov chain to model a node's mobility pattern and capture its social characteristics. A comparison with state‐of‐the‐art algorithms demonstrates that PreS can yield better performance in terms of delivery ratio and delivery latency, and it can provide a comparable performance with the epidemic routing algorithm with lower resource consumption. Copyright © 2013 John Wiley & Sons, Ltd.
Activating secondary metabolism with stress and chemicals
Authors: Yoon Vanessa , Nodwell Justin R 
Published: December 2013

Abstract
The available literature on the secondary or nonessential metabolites of the streptomycetes bacteria suggests that there may be poorly expressed or “cryptic” compounds that have yet to be identified and that may have significant medical utility. In addition, it is clear that there is a large and complex regulatory network that controls the production of these molecules in the laboratory and in nature. Two approaches that have been taken to manipulating the yields of secondary metabolites are the use of various stress responses and, more recently, the use of precision chemical probes. Here, we review the status of this work and outline the challenges and opportunities afforded by each of them.