bluuebunny/crossref_metadata_2025_split huggingface dataset:
Outpatient treatment costs and their potential impact on cancer care
Authors: Isshiki Takahiro 
Published: July 2014

AbstractCancer creates a tremendous financial burden. Cancer‐related costs are categorized into direct, indirect, and psychosocial costs. Although there have been many reports on medical care costs, which are direct, those on other costs are extremely scarce. We estimated travel time and costs required for cancer patients to receive outpatient treatment. We studied 521 cancer patients receiving anti‐cancer treatment between February 2009 and December 2012 at the Outpatient Chemotherapy Center of Teikyo University Chiba Medical Center. Address data were extracted from Data Warehouse electronic medical records, and travel distance and time required for outpatient treatment were calculated via MapInfo and ACT Distance Calculator Package. Transportation costs were estimated on the basis of ¥274 (=$3.00) per kilometer. The study design was approved by an ethics review board of Teikyo University (12–851). Average round‐trip travel distance, time, and cost for all patients were 26.7 km, 72.5 min, and ¥7,303 ($79.99), respectively. Cancer patients incurred a travel cost of ¥4000–¥9000 ($40.00 to $100.00) for each outpatient treatment. With population aging, seniors living alone and senior households are increasing, and outpatient visits are becoming a common burden.
A Remarkable Catalyst Combination to Widen the Operating Temperature Window of the Selective Catalytic Reduction of NO by NH3
Authors: Zhang Runduo , Liu Ning , Luo Zhen , Yang Wei , Liang Xin , Xu Ruinian , Chen Biaohua , Duprez Daniel , Royer Sébastien 
Published: July 2014

AbstractThe front cover artwork for issue 08/2014 is a collaboration between Beijing University of Chemical Technology (P.R. China) and Poitiers University (France). The image shows the principle on catalyst combination for an ideal autoexhaust control covering a broad temperature range. See the Full Paper itself at dx.doi.org/10.1002/cctc.201402514.
Mechanism of Process‐Induced Salt‐to‐Free Base Transformation of Pharmaceutical Products
Authors: Hansen Thomas B. , Qu Haiyan 
Published: July 2014

AbstractThe pH‐solubility profiles of a model drug in salt form were established and the mechanism of salt‐to‐free base form transformation was investigated by increasing pH of the system. Wet massing experiments together with suspension experiments were performed to investigate the effects of excipients on the stability of the salt form. It was found that nucleation of the free base did not happen at pHmax but that instead a new boundary, the pHmetastable, had to be reached before transformation occurred. It was also demonstrated that some excipients influence the stability of the drug, which can help find excipients that previously would have been excluded on basis of a pH higher than pHmax but still lower than pHmetastable.
A self‐guided search for good local minima of the sum‐of‐squared‐error in nonlinear least squares regression
Authors: Vogt Frank 
Published: July 2014

Hard modeling of nonlinear chemical or biological systems is highly relevant as a model function together with values for model parameters provides insights in the systems' functionalities. Deriving values for said model parameters via nonlinear regression, however, is challenging as usually one of the numerous local minima of the sum‐of‐squared errors (SSEs) is determined; furthermore, for different starting points, different minima may be found. Thus, nonlinear regression is prone to low accuracy and low reproducibility. Therefore, there is a need for a generally applicable, automated initialization of nonlinear least squares algorithms, which reaches a good, reproducible solution after spending a reasonable computation time probing the SSE‐hypersurface.For this purpose, a three‐step methodology is presented in this study. First, the SSE‐hypersurface is randomly probed in order to estimate probability density functions of initial model parameter that generally lead to an accurate fit solution. Second, these probability density functions then guide a high‐resolution sampling of the SSE‐hypersurface. This second probing focuses on those model parameter ranges that are likely to produce a low SSE. As the probing continues, the most appropriate initial guess is retained and eventually utilized in a subsequent nonlinear regression.It is shown that this “guided random search” derives considerably better regression solutions than linearization of model functions, which has so far been considered the best‐case scenario. Examples from infrared spectroscopy, cell culture monitoring, reaction kinetics, and image analyses demonstrate the broad and successful applicability of this novel method. Copyright © 2014 John Wiley & Sons, Ltd.
Affinity Polymers Tailored for the Protein A Binding Site of Immunoglobulin G Proteins
Authors: Latza Patricia , Gilles Patrick , Schaller Torsten , Schrader Thomas 
Published: July 2014

AbstractRational design in combination with a screening process was used to develop affinity polymers for a specific binding site on the surface of immunoglobulin G (IgG) proteins. The concept starts with the identification of critical amino acid residues on the protein interface and their topological arrangement. Appropriate binding monomers were subsequently synthesized. Together with a sugar monomer (2–5 equiv) for water solubility and a dansyl monomer (0.5 equiv) as a fluorescent label, they were subjected in aqueous solution to linear radical copolymerization in various compositions (e.g., azobisisobutyronitrile (AIBN), homogeneous water/DMF mixtures). After ultrafiltration and lyophilization, colorless dry water‐soluble powders were obtained. NMR spectroscopic and gel permeation chromatography (GPC) characterization indicated molecular weights between 30 and 500 kD and confirmed retention of monomer composition as well as the absence of monomers. In a competitive enzyme‐linked immunosorbent assay (ELISA) screen of the polymer libraries (20–50 members), few copolymers qualified as strong and selective binders for the protein A binding site on the Fc fragment of the antibody. Their monomer composition precisely reflected the critical amino acids found at the interface. The simple combination of a charged and a nonpolar binding monomer sufficed for selective submicromolar IgG recognition by the synthetic polymer. Affinities were confirmed by fluorescence titrations; they increased with decreasing salt load but remained largely unaltered at lowered pH. Other proteins, including those of similar size and isoelectric point (pI), were bound 10–1000 times less tightly. This example indicates that interaction domains in other proteins may also be targeted by synthetic polymers if their comonomer composition reflects the nature and arrangement of amino acid residues on the protein surface.
ChemInform Abstract: An Organic—Inorganic Hybrid Compound Containing Imidazolium Cations and a One‐Dimensional Lithium Hexacyanidocobaltate‐Based Anionic Framework.
Authors: Shao Xiu‐Dan , Yu Chun‐Hua 
Published: July 2014

Abstract(imiH)2[CoLi(CN)6(H2O)2] (imi: imidazole) is synthesized by reaction of Li3[Co(CN)6] with imidazolium chloride in aqueous solution followed by slow evaporation at room temp.
ChemInform Abstract: Two Ternary Mixed‐Anion Chlorides with Divalent Europium: Eu2H3Cl and Eu7F12Cl2.
Authors: Reckeweg Olaf , DiSalvo Francis J. , Wolf Sarah , Schleid Thomas 
Published: July 2014

AbstractEu2H3Cl (I) and Eu7F12Cl2 (II) are obtained by solid‐state reactions of Eu, NaH, NaCl, and Na (2:4:1:2 molar ratio) or Eu, EuCl3, and LiF (1:1:4 molar ratio), resp.
ChemInform Abstract: Hydrothermally Derived NaLuF4:Yb3+, Ln3+ (Ln3+: Er3+, Tm3+ and Ho3+) Microstructures with Controllable Synthesis, Morphology Evolution and Multicolor Luminescence Properties.
Authors: Gao Yu , Zhao Qian , Xu Zhenhe , Sun Yaguang 
Published: July 2014

AbstractThe title microcrystals are hydrothermally synthesized from aqueous solutions containing LnCl3 (Ln: Lu, Yb, Er, Tm, Ho), sodium citrate as chelating agent, NaBF4, and NaOH (autoclave, pH 10, 180 °C, 24 h).
ChemInform Abstract: Enhanced Thermoelectric Performance in P‐Type AgSbSe2 by Cd‐Doping.
Authors: Guin Satya N. , Chatterjee Arindom , Biswas Kanishka 
Published: July 2014

AbstractCd‐doped p‐type AgSbSe2, AgSb1‐xCdxSe2 (x = 0—0.06) is synthesized from the elements in fused silica tubes (1123 K, 10 h) and characterized by XRD and thermoelectric measurements.
ChemInform Abstract: Additive‐Free Synthesis of V4O7 Hierarchical Structures as High Performance Cathodes for Lithium Ion Batteries.
Authors: Wang Xinran , Zheng Shili , Mu Xuechao , Zhang Yi , Du Hao 
Published: July 2014

AbstractVOx hierarchical structures are solvothermally synthesized from NH4VO3 in a 1:7 mixture of water and ethylene glycol (autoclave, 180 °C, 24 h).
ChemInform Abstract: A New Polymorph of Cd3B2O6: Synthesis, Crystal Structure and Phase Transformation.
Authors: Zhang Xingwen , Yu Hongwei , Wu Hongping , Pan Shilie , Jiao Anqing , Zhang Bingbing , Yang Zhihua 
Published: July 2014

AbstractSmall colorless crystals of the new polymorph β‐Cd3B2O6 are prepared in a PbO—MoO3 flux using a mixture of CdO, H3BO3, PbO, and MoO3 in the molar ratio of 3.3:2:1:1 (Pt crucible, 700 °C).
ChemInform Abstract: Between Oxoborate and Nitridoborate: The Oxonitridoborate Oxide La3(OBN2)O2.
Authors: Dierkes Tobias , Stroebele Markus , Meyer H.‐Juergen 
Published: July 2014

AbstractThe new title compound is prepared by solid state reaction of LaOCl and Li3(BN2) in the molar ratio of 3:1 (sealed Nb ampoule in evacuated silica ampoule, 1200 °C, 12 h, heating and cooling rates of 2 °C/min).
ChemInform Abstract: Preparation and Characterization of Preyssler‐Type Phosphotungstic Acid, H15‐n [P5W30O110Mn+], with Different Encapsulated Cations (M: Na, Ca, Bi, Eu, Y, or Ce), and Their Thermal Stability and Acid Catalyst Properties.
Authors: Takahashi Keita , Sano Tsuneji , Sadakane Masahiro 
Published: July 2014

AbstractThe title heteropolyacids are prepared by exchange of the inner Na+ vs.
ChemInform Abstract: Synthesis and Characterization of Multinuclear Manganese‐Containing Tungstosilicates.
Authors: Kortz Ulrich , et al. et al. 
Published: July 2014

AbstractThe Keggin‐based tungstosilicates containing the anions [MnII3(OH)3(H2O)3 (A‐α‐SiW9O34)]7‐ (IV), [MnIII3(OH)3(H2O)3 (A‐α‐SiW9O34)]4‐ (VIII), [MnIII3(OH)3(H2O)3 (A‐β‐SiW9O34)]4‐ (X), [MnIII3MnIVO3(OAc)3 (A‐α‐SiW9O34)]6‐ (XI), and [MnIII3MnIVO3(OAc)3 (A‐β‐SiW9O34)]6‐ (XII) are characterized by single crystal XRD, IR spectroscopy, and thermogravimetric analysis.
ChemInform Abstract: Fluoroferrates with (dabcoH2)2+ or (dabcoH)+ Cations.
Authors: Darmograi Ganna , Jouffret Laurent , Hemon‐Ribaud Annie , Leblanc Marc , Dujardin Gilles , Maisonneuve Vincent , Lhoste Jerome 
Published: July 2014

Abstract(H2DABCO) [FeIII2F8(H2O)2] (I), (H2DABCO)2 [FeIII2F10]·2H2O (II), (HDABCO)4 [FeIII2F10]·10H2O (III), and (HFDABCO)[(FeII(H2O)6) (FeIIIF6)] (IV) are prepared by conventional solvothermal synthesis using a EtOH or DMF solution of FeF2, FeF3, and HF (4%) with DABCO (autoclave, 120 °C, 72 h) to explore the composition space diagram of the (Fe2+,Fe3+)‐DABCO‐HFaq chemical system.
ChemInform Abstract: Asymmetric Henry Reactions of Aldehydes with Various Nitroalkanes Catalyzed by Copper(II) Complexes of Novel Chiral N‐Monoalkyl Cyclohexane‐1,2‐diamines.
Authors: Liu Fei , Gou Shaohua , Li Lei 
Published: July 2014

AbstractVarious chiral N‐monoalkyl cyclohexane‐1,2‐diamines (I) are synthesized according to a known method and applied as ligands in asymmetric Henry reactions.
ChemInform Abstract: SnAP Reagents for the Synthesis of Piperazines and Morpholines.
Authors: Luescher Michael U. , Vo Cam‐Van T. , Bode Jeffrey W. 
Published: July 2014

AbstractEasily accessible tin (Sn) amine protocol (SnAP) reagents are useful building blocks for the one‐pot synthesis of piperazines and morpholines.
ChemInform Abstract: One‐Pot Synthesis of Multifunctionalized Cyclopropanes.
Authors: Chang Meng‐Yang , Chen Yi‐Chia , Chan Chieh‐Kai 
Published: July 2014

AbstractThe cyclopropanation reaction runs smoothly in a stereoselective manner (cis‐diaryl, trans‐carbonyl) for sulfones carrying an electron‐donating aryl group while electron‐withdrawing aryl groups (NO2‐ or F‐substituted) as well as longer alkyl chains fail.
ChemInform Abstract: Stereocontrolled Syntheses of Tetralone‐ and Naphthyl‐Type Lignans by a One‐Pot Oxidative [3,3] Rearrangement/Friedel—Crafts Arylation.
Authors: Reddel Jordan C. T. , Lutz Kelly E. , Diagne Abdallah B. , Thomson Regan J. 
Published: July 2014

AbstractA stereoselective one‐pot oxidative [3,3] sigmatropic rearrangement/Friedel—Crafts arylation is developed to provide a convenient synthesis of benzhydryl compounds.
ChemInform Abstract: Selective Catalytic Transfer Dehydrogenation of Alkanes and Heterocycles by an Iridium Pincer Complex.
Authors: Yao Wubing , Zhang Yuxuan , Jia Xiangqing , Huang Zheng 
Published: July 2014

AbstractA new phosphinothious/phosphinite Ir pincer complex is prepared and successfully applied as catalyst for the transfer dehydrogenation of a variety of heterocycles using 3,3‐dimethylbuten as hydrogen acceptor.
ChemInform Abstract: Direct Synthesis of 1,4‐Diols from Alkenes by Iron‐Catalyzed Aerobic Hydration and C—H Hydroxylation.
Authors: Hashimoto Takuma , Hirose Daisuke , Taniguchi Tsuyoshi 
Published: July 2014

AbstractA broad variety of 1,4‐diols are prepared from alkenes through an unique iron‐catalyzed aerobic hydration process.
ChemInform Abstract: Preparation of Polymer‐Bound Palladium Catalyst and Its Application to the Reduction of Nitro Arenes and the Hydrodehalogenation of Aryl Halides.
Authors: Min Hongkeun , Lee Sunyoung , Park Minhan , Hwang Jinil , Jung Hyun Min , Lee Sunwoo 
Published: July 2014

AbstractPdO nanoparticles bound on the surface of polystyrene beads are used as catalytic system for the reduction of nitroarenes and for the hydrodehalogenation of aryl halides, respectively.
ChemInform Abstract: Nickel‐Catalyzed C—H Alkylations: Direct Secondary Alkylations and Trifluoroethylations of Arenes.
Authors: Song Weifeng , Lackner Sebastian , Ackermann Lutz 
Published: July 2014

AbstractThe first Ni‐catalyzed ortho‐directed C‐H alkylation with challenging secondary alkyl halides is presented.
ChemInform Abstract: Synthesis and Reactivity of Oxygen Chelated Ruthenium Carbene Metathesis Catalysts.
Authors: Zhang Yiran , Shao Mingbo , Zhang Huizhu , Li Yuqing , Liu Dongyu , Cheng Yu , Liu Guiyan , Wang Jianhui 
Published: July 2014

AbstractSix NHC Ru complexes are prepared by etherification of 4‐substituted 2‐(propen‐1‐yl)phenols with either ethyl alpha‐bromopropionate or 2‐bromo‐gamma‐butyrolactone followed by reaction with Grubbs 2nd generation catalyst in the presence of CuCl.
ChemInform Abstract: Palladium‐Catalyzed Oxidative Carbonylation of N‐Allylamines for the Synthesis of β‐Lactams.
Authors: Li Wu , Liu Chao , Zhang Heng , Ye Keyin , Zhang Guanghui , Zhang Wangzheng , Duan Zhengli , You Shuli , Lei Aiwen 
Published: July 2014

AbstractPd‐catalyzed carbonylative cyclization of allylamines (I) offers a convenient synthesis of α‐methylene‐β‐lactams.
ChemInform Abstract: Synthesis, Characterization and Application of Poly(N,N′‐dibromo‐N‐ethylnaphthyl‐ 2,7‐disulfonamide) as an Efficient Catalyst for the Acetylation and Deacetylation Reactions.
Authors: Khazaei Ardeshir , Saednia Shahnaz , Roshani Liela , Kazem‐Rostami Masoud , Zare Abdolkarim 
Published: July 2014

AbstractA new N‐bromo polysulfonamide is prepared and successfully used as catalyst for the acetylation of alcohols, phenols, thiols and amines under solvent‐free conditions as well as the deacetylation of acetate esters in aqueous medium.
ChemInform Abstract: Organozinc Pivalate Reagents: Segregation, Solubility, Stabilization, and Structural Insights.
Authors: Hernan‐Gomez Alberto , Herd Emma , Hevia Eva , Kennedy Alan R. , Knochel Paul , Koszinowski Konrad , Manolikakes Sophia M. , Mulvey Robert E. , Schnegelsberg Christoph 
Published: July 2014

AbstractAn opening study on organozinc pivalate complex salts is presented with a view to the promising air and moisture stability expected for these type of metalorganic reagents.
ChemInform Abstract: Copper‐Catalyzed Intermolecular Trifluoromethylazidation of Alkenes: Convenient Access to CF3‐Containing Alkyl Azides.
Authors: Wang Fei , Qi Xiaoxu , Liang Zhaoli , Chen Pinhong , Liu Guosheng 
Published: July 2014

AbstractSeveral complex alkenyl‐containing steroid and cinchonine derivatives are converted with moderate yields and often good regio‐ and diastereoselectivities.
ChemInform Abstract: Chiral Propargylic Cations as Intermediates in SN1‐Type Reactions: Substitution Pattern, Nuclear Magnetic Resonance Studies, and Origin of the Diastereoselectivity.
Authors: Nitsch Dominik , Huber Stefan M. , Poethig Alexander , Narayanan Arjun , Olah George A. , Prakash G. K. Surya , Bach Thorsten 
Published: July 2014

AbstractThe diastereoselectivity of the reaction is influenced by the steric effects at the C4‐position with the highest being for the compounds bearing a tBu‐group.
ChemInform Abstract: Catalytic Cycloaddition of 2‐Methyleneaziridines with 1,1‐Dicyanoalkenes.
Authors: Takahashi Hiroki , Yasui Seiji , Tsunoi Shinji , Shibata Ikuya 
Published: July 2014

Abstract2‐Methyleneaziridines are used as substrates for the synthesis of cyclopentylidenamines via a [3 + 2] cycloaddition with dicyanoalkenes using Bu2SnI2 as an effective catalyst.
ChemInform Abstract: Broadly Applicable Z‐ and Diastereoselective Ring‐Opening/Cross‐Metathesis Catalyzed by a Dithiolate Ru Complex.
Authors: Koh Ming Joo , Khan R. Kashif M. , Torker Sebastian , Hoveyda Amir H. 
Published: July 2014

AbstractAll the products are obtained with excellent (Z)‐selectivities.
ChemInform Abstract: Rhodium(II)‐Catalyzed Nondirected Oxidative Alkenylation of Arenes: Arene Loading at One Equivalent.
Authors: Vora Harit U. , Silvestri Anthony P. , Engelin Casper J. , Yu Jin‐Quan 
Published: July 2014

AbstractCooperative reoxidation of Rh(II) with cupric trifluoroacetate and vanadium pentoxide proves essential in providing monoalkenylated products, especially with di‐ and trisubstituted arenes.
ChemInform Abstract: Highly Efficient and Selective Photocatalytic Hydrogenation of Functionalized Nitrobenzenes.
Authors: Yang Xiu‐Jie , Chen Bin , Zheng Li‐Qiang , Wu Li‐Zhu , Tung Chen‐Ho 
Published: July 2014

AbstractThe photocatalytic reduction of nitroarenes (I) with triethanolamine proceeds chemoselectively to afford anilines (II), whilst the reaction of 2‐cyanonitrobenzene (III) affords 2‐aminobenzamide (IV).
ChemInform Abstract: Cu(OAc)2‐Catalyzed Remote Benzylic C(sp3)—H Oxyfunctionalization for C—O Formation Directed by the Hindered para‐Hydroxyl Group with Ambient Air as the Terminal Oxidant under Ligand‐ and Additive‐Free Conditions
Authors: Jiang Jian‐An , Chen Cheng , Huang Jian‐Gang , Liu Hong‐Wei , Cao Song , Ji Ya‐Fei 
Published: July 2014

Abstract54 examples
ChemInform Abstract: Substrate‐Directed Hydroacylation: Rhodium‐Catalyzed Coupling of Vinylphenols and Nonchelating Aldehydes.
Authors: Murphy Stephen K. , Bruch Achim , Dong Vy M. 
Published: July 2014

AbstractA catalyst system consisting of a Rh‐complex and a diphosphine allows the branched‐selective hydroacylation of styrenes bearing an ortho‐hydroxy directing group.
ChemInform Abstract: Iridium‐Catalyzed Direct C—H Amidation with Weakly Coordinating Carbonyl Directing Groups under Mild Conditions.
Authors: Kim Jinwoo , Chang Sukbok 
Published: July 2014

AbstractAromatic ketones and esters are directly amidated under mild conditions using an iridium catalyst combined with acetic acid and lithium carbonate as additives.
ChemInform Abstract: Rhodium(III)‐Catalyzed ortho Alkenylation of N‐Phenoxyacetamides with N‐Tosylhydrazones or Diazoesters Through C—H Activation.
Authors: Hu Fangdong , Xia Ying , Ye Fei , Liu Zhenxing , Ma Chen , Zhang Yan , Wang Jianbo 
Published: July 2014

AbstractTwo procedures for the synthesis of ortho‐alkenyl phenols through C‐H bond activation are presented.
ChemInform Abstract: Metal‐Free Aminosulfonylation of Aryldiazonium Tetrafluoroborates with DABCO·(SO2)2 and Hydrazines.
Authors: Zheng Danqing , An Yuanyuan , Li Zhenhua , Wu Jie 
Published: July 2014

AbstractUncatalyzed coupling of aryldiazonium tetrafluoroborates with N,N‐disubstituted hydrazines and the DABCO bis‐SO2‐adduct offers a smooth and rapid synthesis of arylsulfonium hydrazides.
ChemInform Abstract: Direct Cross‐Coupling Access to Diverse Aromatic Sulfide: Palladium‐Catalyzed Double C—S Bond Construction Using Na2S2O3 as a Sulfurating Reagent.
Authors: Qiao Zongjun , Wei Jianpeng , Jiang Xuefeng 
Published: July 2014

AbstractAromatic thioethers are efficiently synthesized by cross‐coupling of (het)aryl halides with alkyl chlorides in the presence of odorless and stable solid sodium thiosulfate.
ChemInform Abstract: S‐((Phenylsulfonyl)difluoromethyl)thiophenium Salts: Carbon‐Selective Electrophilic Difluoromethylation of β‐Ketoesters, β‐Diketones, and Dicyanoalkylidenes.
Authors: Wang Xin , Liu Guokai , Xu Xiu‐Hua , Shibata Naoyuki , Tokunaga Etsuko , Shibata Norio 
Published: July 2014

AbstractThe synthesis of the difluoromethylating agent (II) is described.
ChemInform Abstract: A Simple and Efficient Tetradentate Schiff Base Derived Palladium Complex for Suzuki—Miyaura Reaction in Water.
Authors: Dewan Anindita , Bora Utpal , Borah Geetika 
Published: July 2014

AbstractA simple catalytic system based on a Pd‐complex of a tetradentate Schiff base promotes the Suzuki—Miyaura cross‐coupling reaction of aryl bromides in water as the solvent.
ChemInform Abstract: Pd Nanoparticles Immobilized on PNIPAM—Halloysite: Highly Active and Reusable Catalyst for Suzuki—Miyaura Coupling Reactions in Water.
Authors: Hong Myeng Chan , Ahn Hyunseok , Choi Myung Chan , Lee Yongwoo , Kim Jongsik , Rhee Hakjune 
Published: July 2014

AbstractPreparation and characterization (TEM, X‐ray, DSC) of the catalyst are given as well.
ChemInform Abstract: Ruthenium‐Catalyzed Cascade C—H Functionalization of Phenylacetophenones.
Authors: Mehta Vaibhav P. , Garcia‐Lopez Jose‐Antonio , Greaney Michael F. 
Published: July 2014

AbstractA Ru(II)‐catalyzed C‐H functionalization that allows three different functionalizations of arylacetophenones with activated olefins is developed.
ChemInform Abstract: Introduction of an Arylethynyl Group onto an Anthracene Bisimide Core for Molecular Design of New π‐Conjugated Compounds.
Authors: Iwanaga Tetsuo , Tanaka Ryo , Toyota Shinji 
Published: July 2014

AbstractNovel, strongly fluorescent donor‐acceptor substituted anthracene bisimides (III) and (V) are prepared via Sonogashira and Stille couplings.
ChemInform Abstract: Rhodium(I)‐Catalyzed Cyclization of Allenynes with a Carbonyl Group Through Unusual Insertion of a C=O Bond into a Rhodacycle Intermediate.
Authors: Oonishi Yoshihiro , Yokoe Takayuki , Hosotani Akihito , Sato Yoshihiro 
Published: July 2014

AbstractNovel Rh‐catalyzed cyclizations of allenynes with a tethered carbonyl group are presented.
ChemInform Abstract: Rhodium(I)‐Catalyzed Decarbonylative Spirocyclization Through C—C Bond Cleavage of Benzocyclobutenones: An Efficient Approach to Functionalized Spirocycles.
Authors: Xu Tao , Savage Nikolas A. , Dong Guangbin 
Published: July 2014

AbstractA range of diverse spirocycles are synthesized in good to excellent yields and many sensitive functional groups are tolerated.
ChemInform Abstract: Enantioselective Allylation of Thiophene‐2‐carbaldehyde: Formal Total Synthesis of Duloxetine.
Authors: Motloch Petr , Valterova Irena , Kotora Martin 
Published: July 2014

AbstractOptimized reaction conditions are developed for the enantioselective allylation of thiophen‐2‐carbaldehyde.
ChemInform Abstract: Chiral Phosphorus‐Based 1,3‐Dipoles: A Modular Approach to Enantioselective 1,3‐Dipolar Cycloaddition and Polycyclic 2‐Pyrroline Synthesis.
Authors: Morin Marie S. T. , Arndtsen Bruce A. 
Published: July 2014

AbstractThe title chiral dipoles generated in situ from the corresponding imines, chiral phosphites, and acid chlorides, undergo intramolecular alkene cycloaddition with high enantioselectivity.