bluuebunny/crossref_metadata_2025_split huggingface dataset:
The demography of a newly establishedOspreyPandion haliaetuspopulation inFrance
Authors: Wahl Rolf , Barbraud Christophe 
Published: November 2013

Using long‐term mark–resighting data acquired over 27 years in continentalFrance, we estimated demographic parameters and modelled the dynamics of a newly established population ofOspreysPandion haliaetususing a life‐history model. We then performed prospective and retrospective analyses to estimate the sensitivity of the population growth rate to demographic parameters, and to quantify their contribution to the observed variation in abundance. The observed population growth rate was estimated at 1.150 (from one to 38 pairs in the period 1985–2011), and the stochastic population growth rate was estimated at 1.156. The number of fledglings per nest made the largest contribution to the variance of the observed population growth rate. Breeding productivity was stable across years. In contrast, the prospective analysis indicated that the sensitivity of the population growth rate was greatest for immigration and adult survival. Our results suggest that the increase of a new and recently established breeding population ofOspreys was mainly driven by local dynamics (high productivity and high proportion of breeding individuals), with no sign of density‐dependence except for juvenile survival. This probably reflects highly favourable conditions for breeding. Our results show that productivity can be a major driver in recovering raptor populations, and conservation work should aim to protect occupied nest‐sites and their surrounding habitat and to maintain highly favourable foraging areas in the vicinity of breeding sites.
Integrating pharmacists into primary care teams: barriers and facilitators
Authors: Jorgenson Derek , Laubscher Tessa , Lyons Barry , Palmer Rebecca 
Published: November 2013

Abstract

Objectives
This study evaluated the barriers and facilitators that were experienced as pharmacists were integrated into 23 existing primary care teams located in urban and rural communities in Saskatchewan, Canada.

Methods
Qualitative design using data from one-on-one telephone interviews with pharmacists, physicians and nurse practitioners from the 23 teams that integrated a new pharmacist role. Four researchers from varied backgrounds used thematic analysis of the interview transcripts to determine key themes. The research team met on multiple occasions to agree on the key themes and received written feedback from an external auditor and two of the original interviewees.

Key findings
Seven key themes emerged describing the barriers and facilitators that the teams experienced during the pharmacist integration: (1) relationships, trust and respect; (2) pharmacist role definition; (3) orientation and support; (4) pharmacist personality and professional experience; (5) pharmacist presence and visibility; (6) resources and funding; and (7) value of the pharmacist role. Teams from urban and rural communities experienced some of these challenges in unique ways.

Conclusions
Primary care teams that integrated a pharmacist experienced several common barriers and facilitators. The negative impact of these barriers can be mitigated with effective planning and support that is individualized for the type of community where the team is located.
Standing laparoscopic inguinal hernioplasty using cyanoacrylate for preventing recurrence of acquired strangulated inguinal herniation in 10 stallions
Authors: Rossignol Fabrice , Mespoulhes‐Rivière Céline , Vitte Amélie , Lechartier Antoine , Boening Karl Joseph 
Published: November 2013

ObjectiveTo describe a technique for standing inguinal hernioplasty in horses using cyanoacrylate glue, and to evaluate its effect on prevention of recurrent inguinal herniation in stallions that had previous acquired strangulated inguinal hernia (SIH).Study designCase series.AnimalsStallions (n = 10) with a history of SIH.MethodsHernioplasty was performed in standing horses using 4 laparoscopic portals. The mesorchium was retracted caudomedially using Babcock forceps. A flexible polyethylene extension tube was introduced through the sheath of a laparoscopic needle andn‐butyl‐2‐cyanoacrylate (2 mL) was injected into the inguinal canal including its margins while a 2nd Babcock forceps prevented deep ventral diffusion of the cyanoacrylate. The craniolateral parts of the vaginal ring were compressed until full adhesion between the visceral and parietal walls was achieved. In 2 horses, the lateral part of the vaginal ring was sutured before gluing. A contralateral approach was used to check the caudomedial part of the vaginal ring.ResultsNo recurrence (1–4 years) of inguinal hernia was reported. No major complications occurred and cosmetic outcome was excellent. All horses were used for their intended purpose and 7 horses being used as breeding stallions remained fertile.ConclusionStanding inguinal hernioplasty using cyanoacrylate seems to provide efficient and secure closure of the vaginal ring in stallions.
Mapping Alberta's surface water resources for the period 1971–2000
Authors: Kienzle Stefan W. , Mueller Markus 
Published: November 2013

AbstractAlthough the sustainability and wealth of Alberta is closely linked to the quantity, quality, and management of its water resources, the province lacks watershed‐based inventories of its water supplies. The mean annual water yield for 287 gauged watersheds across Alberta was calculated for the period 1971–2000 by relating available streamflow records with the respective watershed areas. The percent contribution of each watershed relative to the outlet of each of the 16 major river basins located in Alberta was computed, which enabled the identification of the most important water‐producing regions. The integration of high‐resolution precipitation normal maps, available for the same period, enabled the calculation of mean annual runoff coefficients and the determination of mean annual regional water balances. These analyses resulted in important water resources baseline data, against which impacts of environmental and climate change can be compared. All data are available online in the form of spreadsheets and shapefiles.
High Correlation of Estimated Local Conduction Velocity with Natural Logarithm of Bipolar Electrogram Amplitude in the Reentry Circuit of Atrial Flutter
Authors: ITOH TAIHEI , KIMURA MASAOMI , SASAKI SHINGO , OWADA SHINGEN , HORIUCHI DAISUKE , SASAKI KENICHI , ISHIDA YUJI , TAKAHIKO KINJO , OKUMURA KEN 
Published: November 2013

Relation of Electrogram Amplitude to Conduction VelocityBackgroundLow conduction velocity (CV) in the area showing low electrogram amplitude (EA) is characteristic of reentry circuit of atypical atrial flutter (AFL). The quantitative relationship between CV and EA remains unclear. We characterized AFL reentry circuit in the right atrium (RA), focusing on the relationship between local CV and bipolar EA on the circuit.Methods and ResultsWe investigated 26 RA AFL (10 with typical AFL; 10 atypical incisional AFL; 6 atypical nonincisional AFL) using CARTO system. By referring to isochronal and propagation maps delineated during AFL, points activated faster on the circuit were selected (median, 7 per circuit). At the 196 selected points obtained from all patients, local CV measured between the adjacent points and bipolar EA were analyzed. There was a highly significant correlation between local CV and natural logarithm of EA (lnEA) (R2 = 0.809, P < 0.001). Among 26 AFL, linear regression analysis of mean CV, calculated by dividing circuit length (152.3 ± 41.7 mm) by tachycardia cycle length (TCL) (median 246 msec), and mean lnEA, calculated by dividing area under curve of lnEA during one tachycardia cycle by TCL, showed y = 0.695 + 0.191x (where: y = mean CV, x = lnEA; R2 = 0.993, P < 0.001). Local CV estimated from EA with the use of this formula showed a highly significant linear correlation with that measured by the map (R2 = 0.809, P < 0.001).ConclusionThe lnEA and estimated local CV show a highly positive linear correlation. CV is possibly estimated by EA measured by CARTO mapping.
Dawn; the Vesta–HED connection; and the geologic context for eucrites, diogenites, and howardites
Authors: McSween Harry Y. , Binzel Richard P. , De Sanctis M. Cristina , Ammannito Eleonora , Prettyman Thomas H. , Beck Andrew W. , Reddy Vishnu , Le Corre Lucille , Gaffey Michael J. , McCord Thomas B. , Raymond Carol A. , Russell Christopher T. ,   the Dawn Science Team
Published: November 2013

AbstractThe Dawn mission has provided new evidence strengthening the identification of asteroid Vesta as the parent body of the howardite, eucrite, and diogenite (HED) meteorites. The evidence includes Vesta's petrologic complexity, detailed spectroscopic characteristics, unique space weathering, diagnostic geochemical abundances and neutron absorption characteristics, chronology of surface units and impact history, occurrence of exogenous carbonaceous chondritic materials in the regolith, and dimensions of the core, all of which are consistent with HED observations and constraints. Global mapping of the distributions of HED lithologies by Dawn cameras and spectrometers provides the missing geologic context for these meteorites, thereby allowing tests of petrogenetic models and increasing their scientific value.
Composition and petrology of HED polymict breccias: The regolith of (4) Vesta
Authors: Mittlefehldt David W. , Herrin Jason S. , Quinn Julie E. , Mertzman Stanley A. , Cartwright Julia A. , Mertzman Karen R. , Peng Zhan X. 
Published: November 2013

AbstractWe have done petrologic and compositional studies on a suite of polymict eucrites and howardites to better understand regolith processes on their parent asteroid, which we accept is (4) Vesta. Taking into account noble gas results from companion studies, we interpret five howardites to represent breccias assembled from the true regolith: Elephant Moraine (EET) 87513, Grosvenor Mountains (GRO) 95535, GRO 95602, Lewis Cliff (LEW) 85313, and Meteorite Hills (MET) 00423. We suggest that EET 87503 is paired with EET 87513, and thus is also regolithic. Pecora Escarpment (PCA) 02066 is dominated by melt‐matrix clasts, which may have been formed from true regolith by impact melting. These meteorites display a range in eucrite:diogenite mixing ratio from 55:45 to 76:24. There is no correlation between degree of regolith character and Ni content. The Ni contents of howardite, eucrite, and diogenites (HEDs) are mostly controlled by the distribution of coarse chondritic clasts and metal grains, which in some cases resulted from individual, low‐velocity accretion events, rather than extensive regolith gardening. Trace element compositions indicate that the mafic component of HED polymict breccias is mostly basalt similar to main‐group eucrites; Stannern‐trend basaltic debris is less common. Pyroxene compositions show that some trace element‐rich howardites contain abundant debris from evolved basalts, and that cumulate gabbro debris is present in some breccias. The scale of heterogeneity varies considerably; regolithic howardite EET 87513 is more homogeneous than fragmental howardite Queen Alexandra Range (QUE) 97001. Individual samples of a given howardite can have different compositions even at roughly 5 g masses, indicating that obtaining representative meteorite compositions requires multiple or large samples.
Evaluating summary statistics used to test for incomplete lineage sorting: mito‐nuclear discordance in the reef sponge Callyspongia vaginalis
Authors: DeBiasse Melissa B. , Nelson Bradley J. , Hellberg Michael E. 
Published: November 2013

AbstractConflicting patterns of population differentiation between the mitochondrial and nuclear genomes (mito‐nuclear discordance) have become increasingly evident as multilocus data sets have become easier to generate. Incomplete lineage sorting (ILS) of nucDNA is often implicated as the cause of such discordance, stemming from the large effective population size of nucDNA relative to mtDNA. However, selection, sex‐biased dispersal and historical demography can also lead to mito‐nuclear discordance. Here, we compare patterns of genetic diversity and subdivision for six nuclear protein‐coding gene regions to those for mtDNA in a common Caribbean coral reef sponge, Callyspongia vaginalis, along the Florida reef tract. We also evaluated a suite of summary statistics to determine which are effective metrics for comparing empirical and simulated data when testing drivers of mito‐nuclear discordance in a statistical framework. While earlier work revealed three divergent and geographically subdivided mtDNACOI haplotypes separated by 2.4% sequence divergence, nuclear alleles were admixed with respect to mitochondrial clade and geography. Bayesian analysis showed that substitution rates for the nuclear loci were up to 7 times faster than for mitochondrial COI. Coalescent simulations and neutrality tests suggested that mito‐nuclear discordance in C. vaginalis is not the result of ILS in the nucDNA or selection on the mtDNA but is more likely caused by changes in population size. Sperm‐mediated gene flow may also influence patterns of population subdivision in the nucDNA.
Interdisciplinary Treatment of Patients with Fibromyalgia: Improvement of Their Health‐Related Quality of Life
Authors: Martín Josune , Torre Fernando , Padierna Angel , Aguirre Urko , González Nerea , Matellanes Begoña , Quintana José M. 
Published: November 2013

AbstractObjectiveTo assess whether an interdisciplinary intervention is more effective than usual care for improving the health‐related quality of life (HRQoL) among patients with fibromyalgia (FM), and to identify variables that were predictors of improvement inHRQoL.MethodsIn a randomized controlled clinical trial carried out on an outpatient basis in a hospital pain management unit, 153 patients withFMwere randomly allocated to an experimental group (EG) or a control group (CG). Participants completed the Fibromyalgia Impact Questionnaire (FIQ) at baseline and 6 months after the intervention. TheEGreceived an interdisciplinary treatment (12 sessions for 6 weeks) which consisted of coordinated psychological, medical, educational, and physiotherapeutic interventions while theCGreceived standard‐of‐care pharmacologic treatment. Descriptive statistics,ANOVA,Chi square andFisher tests and generalized linear models were used for data analysis.ResultsSix months after the intervention, statistically significant improvements inHRQoLwere observed in physical functioning (P = 0.01), pain (P = 0.03) and totalFIQscore (P = 0.04) in theEGcompared to theCG. The number of physical illnesses was identified as a predictor for improvement.ConclusionsThis interdisciplinary intervention has shown effectiveness in improving theHRQoLof this sample of patients withFM. The number of physical illnesses was identified as a predictor of that improvement.
Subcutaneous Injection of Diclofenac for the Treatment of Pain Following Minor Orthopedic Surgery (DIRECT study): A Randomized Trial
Authors: Chiarello Eugenio , Bernasconi Stefano , Gugliotta Barbara , Giannini Sandro 
Published: November 2013

AbstractObjectivesParenteral diclofenac is frequently used for analgesia following minor orthopedic interventions. Currently available diclofenac formulations are for intramuscular (IM) or intravenous injection. A new 1 mL volume formulation of diclofenac containing hydroxypropyl‐β‐cyclodextrin (HPβCD) allows both SC and IM administration. The objective of this open‐label, randomized, parallel group, active‐controlled study was to assess the safety and efficacy of 75 mg diclofenac HPβCD, administered SC or IM, compared with IM Voltaren® 75 mg in inpatients undergoing minor orthopedic surgeries with moderate‐to‐severe postoperative pain.MethodsA total of 325 patients were randomized to treatment. Surgery‐related pain was comparable between groups before treatment and rapidly declined in all patients following diclofenac injection. The primary endpoint was investigator‐assessed local tolerability up to 18 hours postinjection (redness, swelling, and hardening at the injection site each scored on a 4‐point scale where 0 = none, 1 = mild, 2 = moderate, and 3 = severe).ResultsLocal tolerability was found to be optimal for all the injected formulations, with mean overall scores (0 to 9) of 0.57, 0.31, and 0.26, for diclofenac HPβCD SC, diclofenac HPβCD IM, and Voltaren® IM, respectively. Consistently, the overall tolerability as judged by the patients and investigators was reported as good or excellent in more than 90% of cases in all groups.ConclusionsOverall, the study results indicate that safety and efficacy were similar irrespective of the diclofenac formulation used; thus, the new SC diclofenac HPβCD has an acceptable tolerability profile and may be considered a valid alternative to IM‐delivered diclofenac formulations.
A Comprehensive Drug Safety Evaluation of Pregabalin in Peripheral Neuropathic Pain
Authors: Freynhagen Rainer , Serpell Michael , Emir Birol , Whalen Ed , Parsons Bruce , Clair Andrew , Latymer Mark 
Published: November 2013

AbstractPregabalin is a commonly used therapy currently recommended as first‐line treatment for a number of neuropathic pain (NeP) conditions. Since licensure, a number of clinical trials of pregabalin in different NeP conditions have been completed from which additional data on safety and tolerability can be drawn. In this analysis, patient‐level data from 31 randomized clinical trials of pregabalin in peripheral NeP sponsored by Pfizer were pooled and assessed for incidence of adverse events (AEs). Incidence by age, disease condition, and race, together with risk differences and time to onset and resolution of AEs, was assessed. In total, 7,510 patients were included: 4,884 on pregabalin (representing 805 patient‐years treatment) and 2,626 on placebo. Pregabalin vs. placebo risk analysis identified 9 AEs with a risk difference, for which the lower limit of the 95% confidence interval (CI) was > 1%: dizziness (risk difference [95% CI]: (17.0 [15.4 to 18.6]), somnolence (10.8 [9.5 to 12.1]), peripheral edema (5.4 [4.3 to 6.4]), weight increase (4.7 [3.9 to 5.5]), dry mouth (2.9 [2.1 to 3.8]), constipation (2.3 [1.5 to 3.2]), blurred vision (2.2 [1.6 to 2.9]), balance disorder (2.0 [1.5 to 2.5]), and euphoric mood (1.6 [1.2 to 2.0]). The most common AEs, dizziness and somnolence, typically emerged within the first 1 to 2 weeks of treatment and resolved 1 to 2 weeks later, without resulting in cessation of treatment. The data from this review provide information, indicating which AEs may be expected in patients treated with pregabalin, and suggest that careful dose titration to the highest tolerable dose is the most appropriate approach in clinical practice.
Policy Language in Restoration Ecology
Authors: Jørgensen Dolly , Nilsson Christer , Hof Anouschka R. , Hasselquist Eliza M. , Baker Susan , Chapin F. Stuart , Eckerberg Katarina , Hjältén Joakim , Polvi Lina , Meyerson Laura A. 
Published: November 2013

AbstractRelating restoration ecology to policy is one of the aims of the Society for Ecological Restoration and its journal Restoration Ecology. As an interdisciplinary team of researchers in both ecological science and political science, we have struggled with how policy‐relevant language is and could be deployed in restoration ecology. Using language in scientific publications that resonates with overarching policy questions may facilitate linkages between researcher investigations and decision‐makers' concerns on all levels. Climate change is the most important environmental problem of our time and to provide policymakers with new relevant knowledge on this problem is of outmost importance. To determine whether or not policy‐specific language was being included in restoration ecology science, we surveyed the field of restoration ecology from 2008 to 2010, identifying 1,029 articles, which we further examined for the inclusion of climate change as a key element of the research. We found that of the 58 articles with “climate change” or “global warming” in the abstract, only 3 identified specific policies relevant to the research results. We believe that restoration ecologists are failing to include themselves in policy formation and implementation of issues such as climate change within journals focused on restoration ecology. We suggest that more explicit reference to policies and terminology recognizable to policymakers might enhance the impact of restoration ecology on decision‐making processes.
The effect of topical ophthalmic 1% atropine on heart rate and rhythm in normal dogs
Authors: Greenberg Shari , Plummer Caryn , Maisenbacher Herbert , Friary John , Berg Alexia 
Published: November 2013

AbstractObjectiveTo determine if topically administered ophthalmic atropine affects heart rate or rhythm in clinically normal dogs.MethodsTwo groups of 15 healthy dogs were evaluated, one consisting of dogs weighing <15 kg, the other consisting of dogs weighing >15 kg. Each dog was suited with a Holter monitor. At start time 0, dogs received one drop of ophthalmic 1% atropine solution, or one drop of sterile saline solution as a control in each eye, via random assignment. Each dog served as their own control. This procedure was repeated two more times, at 6‐h intervals, for a total of three treatments over a 12‐h period. Holter monitors recorded heart rate and rhythm for 24 h. Statistical analysis was performed to compare values between the groups. Dose dependent changes in cardiac parameters were evaluated.ResultsThe mean heart rate and average minimum heart rate was significantly higher during the treatment period compared to the control period (8% and 13%, respectively). The mean number of hours with a heart rate <50 bpm decreased by 47% in the treatment vs. the control period. The mean maximum heart rate and number of h with a heart rate > 180 bpm did not differ significantly between the two groups. There was no evidence of dose dependence on heart rate when comparing small and large dogs. No significant differences in heart rhythm were noted between groups for measurable parameters.ConclusionsTopically administered atropine causes a small but significant increase in heart rate in healthy dogs.