bluuebunny/crossref_metadata_2025_split huggingface dataset:
Managing across borders and cultures
Authors: Reilly Peter 
Published: April 2015

Purpose
– The aim of this paper is to ask why western organisations appear to be moving towards a single global HR model that minimises cultural differences compared with Asian organisations that seem to allow more variation in HR policies and practices. Moreover, we try to identify the problems western organisations face in taking this route and how they seek to overcome them.

Design/methodology/approach
– The paper is based on a case survey approach whereby the author (and colleague) researched the global HR practices of some 70 organisations, interviewing a good proportion of the senior HR managers in these organisations. The focus was on global employment brands, culture and diversity, as well as talent management and HR service delivery model.

Findings
– Western organisations seem to be moving towards a single global HR model that minimises cultural differences, whereas “polycentric” organisational forms are common in Asian companies. This may be to do with ownership structure and business model, but is also through Western organisations fashioning a “one company” philosophy and reducing costs through centralisation. This approach risks the creation of an ethnocentric world view based on a home country perspective that might damage diversity and lead to the cloning of the business leadership. The paper offers some risk mitigation strategies based around having common people principles but allowing distinctive local practice.

Research limitations/implications
– The research is case study-based. There is no quantitative element to the results. Thus, the research has the benefit of in-depth understanding of organisational practice and its context, and the author (and colleague) do not have the benefit of testing the findings across a larger number of organisations. In particular, the East versus West distinction the author (and colleague) made needs further refinement. And, the author would want to look in more depth at the business structures of Western firms to see how much effect they have on organisational culture.

Practical implications
– Organisations can take the findings, including solutions to the problems of ethnocentricity, and apply them to their own situations. In particular, it should encourage a more thoughtful review of the development of organisational culture and especially reflection on the dangers of standardisation and consolidation of HR services.

Originality/value
– This paper is based on original case study research and uses these insights to consider some of the academic debates about organisational culture and HR services, specifically within the context of global operations. The advice to organisations will be new to practitioners, although it builds on previous work.
Adaptation of international guidelines on assessment and management of cancer pain for the Australian context
Authors: Lovell Melanie , Luckett Tim , Boyle Frances , Stubbs John , Phillips Jane , Davidson Patricia Mary , Olver Ian , von Dincklage Jutta , Agar Meera 
Published: April 2015

AbstractAimTo develop clinical practice guidelines for screening, assessing and managing cancer pain in Australian adults.MethodsThis three‐phase project utilized the ADAPTE approach to adapt international cancer pain guidelines for the Australian setting. A Working Party was established to define scope, screen guidelines for adaptation and develop recommendations to support better cancer pain control through screening, assessment, pharmacological and non‐pharmacological management, and patient education. Recommendations with limited evidence were referred to Expert Panels for advice before the draft guidelines were opened for public consultation via the Cancer Council Australia Cancer Guidelines Wiki platform in late 2012. All comments were reviewed by the Working Party and the guidelines were revised accordingly.ResultsScreening resulted in six international guidelines being included for adaptation – those developed by the Scottish Intercollegiate Guidelines Network (2008), National Health Service Quality Improvement Scotland (2009), National Comprehensive Cancer Network (2012), European Society of Medical Oncology (2011), European Association for Palliative Care (2011, 2012) and National Institute of Clinical Excellence (2012). Guideline adaptation resulted in 55 final recommendations. The guidelines were officially launched in November 2013.ConclusionInternational guidelines can be efficiently reconfigured for local contexts using the ADAPTE approach. Availability of the guidelines via the Cancer Council Australia Wiki is intended to promote uptake and enable recommendations to be kept up to date. Resources to support implementation will also be made available via the Wiki if found to be effective by a randomized controlled trial commencing in 2015.
Solitary pituitary metastasis from HER2‐positive breast cancer
Authors: Kam Jeremy , Kam Jeffrey , Mann G Bruce , Phillips Claire , Wentworth John M , King James , Lindeman Geoffrey J 
Published: April 2015

AbstractThe introduction of anti‐HER2 therapy with trastuzumab has seen an increase in frequency of central nervous system metastasis as the site of first recurrence. Here, we present a rare case of a 63‐year‐old woman who presented with an isolated breast carcinoma pituitary metastasis 5 years following treatment for a high‐risk breast cancer. This report underscores the changing nature of HER2‐positive disease in the post‐trastuzumab era.
Mark Sacks Lecture 2013: Spinoza on Goodness and Beauty and the Prophet and the Artist
Authors: Gatens Moira 
Published: April 2015

AbstractSome critics have claimed that Spinoza's philosophy has nothing to offer aesthetics. I argue that within his conception of an ars vivendi one can discern a nascent theory of art (ars). I bring the figure of the prophet in relation to that of the artist and, alongside a consideration of Spinoza's views on goodness and beauty, show that the special talent of the artist should be understood in terms of the entirely natural expression of the conatus.
Efficacy and safety of telbivudine in different trimesters of pregnancy with high viremia for interrupting perinatal transmission of hepatitis B virus
Authors: Liu Yingxia , Wang Miao , Yao Simin , Yuan Jing , Lu Jian , Li Huijuan , Zeng Wen , Deng Yong , Zou Rongrong , Li Jie , Xiao Jia 
Published: April 2015

AbstractAimWe aimed to investigate the efficacy and safety of telbivudine (LdT) on the intervention of mother‐to‐child transmission (MTCT) in different trimesters of pregnant women with high viral loads.MethodsIn this prospective cohort study, 160 cases of mothers with high viral loads were included. Eighty‐two subjects received 600 mg/day LdT therapy. Fifty of them started LdT therapy before the third trimester of gestation, including 17 cases before pregnancy, nine and 24 cases in the first and second trimesters of pregnancy, respectively. The other 32 cases started LdT in the third trimester of gestation. Control pregnant women (78 cases) did not take LdT therapy. MTCT rate was determined by hepatitis B surface antigen (HBsAg) and hepatitis B virus (HBV) DNA data of infants at the 51st week post‐partum. Adverse events were also evaluated throughout the study.ResultsOne hundred and sixty infants were born from 160 pregnant women. Both LdT‐treated groups displayed a marked decline in HBV DNA levels from the beginning to delivery. Positive rate of serum HBsAg in infants born from the above two groups of mothers were 0% and 3.1%, respectively, which was significantly lower than that in the untreated controls (24.4%). The incidence of detectable HBV DNA levels was significantly lower in infants born to LdT‐treated mothers than in the controls (16.7%) at the 51st week post‐partum. No infant had birth defects. No severe adverse event or complication were observed in LdT‐treated mothers or infants followed until the 51st week post‐partum.ConclusionThe earlier application of LdT during pregnancy, the better preventive effects it offered on MTCT.
Excessive range of statin dose in Western Australian primary care
Authors: Dimmitt S. B. , Moran A. , Scartozzi M. , Stampfer H. G. , Warren J. B. 
Published: April 2015

AbstractBackgroundStatins are very effective in reducing coronary disease and ischaemic stroke but guidelines although evolving have not been clear on statin dose.AimTo audit and review community statin prescribing.MethodsA retrospective audit of the type and dose of statin dispensed was undertaken at five pharmacies in and around Perth, the capital city of Western Australia. Patients were de‐identified.ResultsStatins made up 6.5% of all prescriptions. Statin dose when adjusted for different potency effectively varied 64‐fold between patients. Rosuvastatin and atorvastatin accounted for 79% of prescriptions, at a mean dose of 10 times the effective dose 50.ConclusionThe extraordinarily wide variation in statin dose is at odds with the more consistent doses of other drugs used in the management of arterial disease. Unnecessarily high statin dosing increases side‐effects and may not improve clinical outcomes appreciably. Rational prescribing of statins based on the pharmacodynamic evidence, with lower doses in most patients, combined with close attention to reduction of smoking, blood pressure and weight, is likely to reduce arterial disease most efficiently and safely.
News/Interview/Editorial
Authors: Tarran Brian , Wininger Michael 
Published: April 2015

Abstract
Canadian MP fights to reinstate the long-form census. The White House appoints a chief data scientist. Cosmic dust busts ‘evidence’ for inflation. Why random is too random for Spotify customers. Back to the drawing board for the Mars One mission? The New York blizzard that never was. A psychology journal bans p-values.
The responsiveness of the International Prostate Symptom Score, Incontinence Impact Questionnaire‐7 and Depression, Anxiety and Stress Scale‐21 in patients with lower urinary tract symptoms
Authors: Choi Edmond P.H. , Chin Weng Yee , Lam Cindy L.K. , Wan Eric Y.F. 
Published: April 2015

AbstractAimsTo examine the responsiveness of a combined symptom severity and health‐related quality of life measure, condition‐specific health‐related quality of life measure and mental health measure in patients with lower urinary tract symptoms.BackgroundTo establish the responsiveness of measures that accurately capture the change in health status of patients is crucial before any longitudinal studies can be appropriately planned and evaluated.DesignProspective longitudinal observational study.Methods402 patients were surveyed at baseline and 1‐year using the International Prostate Symptom Score, the Incontinence Impact Questionnaire‐7 and Depression, Anxiety and Stress Scales‐21. The internal and external responsiveness were assessed. Surveys were conducted from March 2013–July 2014.ResultsIn participants with improvements, the internal responsiveness for detecting positive changes was satisfactory in males and females for all scales, expect for the Depression subscale. The health‐related quality of life question of the International Prostate Symptom Score was more externally responsive than the Incontinence Impact Questionnaire‐7.ConclusionsThe International Prostate Symptom Score and Anxiety and Stress subscales were more responsive in males than in females. The symptom questions of the International Prostate Symptom Score and Anxiety and Stress subscales were not externally responsive in females. The health‐related quality of life question of the International Prostate Symptom Score outperformed the Incontinence Impact Questionnaire‐7 in both males and females, in terms of external responsiveness.
Inter‐country exploration of factors associated with admission to long‐term institutional dementia care: evidence from the RightTimePlaceCare study
Authors: Verbeek Hilde , Meyer Gabriele , Challis David , Zabalegui Adelaida , Soto Maria E. , Saks Kai , Leino‐Kilpi Helena , Karlsson Staffan , Hamers Jan P.H. ,   the RightTimePlaceCare Consortium
Published: April 2015

AbstractAimTo explore inter‐country variation of factors associated with institutionalization of people with dementia.BackgroundThere is an urgent need for evidence on whether factors associated with admission to institutional dementia care are applicable across healthcare systems, as increasing evidence suggests that these factors could be country‐specific.DesignA prospective cohort study.MethodPrimary data were collected in eight European countries, at baseline and after 3 months follow‐up (November 2010–April 2012). The sample included 2014 dyads of people with dementia and their informal caregivers; 791 patients were recently institutionalized, 1223 patients lived at home and were at risk of institutionalization. Associations between care setting (institution vs. home) and factors shown to influence institutionalization (e.g. cognition, independence in activities of daily life, behaviour) were studied.ResultsConsiderable differences were found between the eight countries in characteristics of people with dementia who had been recently admitted to ILTC. However, caregiver burden appeared the most consistent factor associated with institutionalization in all analyses. Indications for the importance of independence in activities of daily life were found as well, although country differences may be more prominent for this factor.ConclusionEvidence was found for two common factors, crucial in the process of institutionalization across countries: caregiver burden and independency in activities of daily life. However, this study also suggests that admission to institutional dementia care is context‐specific, as wide variation exists in factors associated with institutionalization across countries. Tailored best‐practice strategies are needed to reflect variations in response to these needs.
Enhancing nurses' empowerment: the role of supervisors' empowering management practices
Authors: Montani Francesco , Courcy François , Giorgi Gabriele , Boilard Amélie 
Published: April 2015

AbstractAimThis study tests a theoretical model where: (a) nurses' dispositional resistance to change is indirectly negatively related to behavioural empowerment through the mediating role of psychological empowerment; and (b) supervisors' empowering management practices buffer both the negative relationship between dispositional resistance to change and psychological empowerment and the indirect negative relationship between resistance to change and behavioural empowerment via psychological empowerment.BackgroundPromoting a high level of empowerment among nursing personnel is important to ensure their effectiveness in the context of organizational change. It is thus essential to advance our current understanding of the factors that hamper nurses' psychological and behavioural expressions of empowerment and to clarify supervisor practices that can overcome such barriers.DesignA cross‐sectional research design.MethodWe collected survey data during 2012 from a sample of 197 nurses from a Canadian hospital undergoing a major organizational change.ResultsResults from moderated mediation analyses provided evidence for an indirect negative relationship between dispositional resistance to change and behavioural empowerment through psychological empowerment, and for a moderating (buffering) effect of supervisors' empowering management practices on this mediated relationship. These findings provided support for our hypotheses.ConclusionsSupervisors' empowering management practices represent an important contextual buffer against the negative effects of dispositional resistance to change on nurses' empowerment. Organizations should develop empowering management skills among nurses' supervisors to counteract the detrimental effects of dispositional resistance to change and to sustain an empowered nursing workforce.
Identification of Low‐Risk Adult Congenital LQTS Patients
Authors: ZHANG CLAIRE , KUTYIFA VALENTINA , MCNITT SCOTT , ZAREBA WOJCIECH , GOLDENBERG ILAN , MOSS ARTHUR J. 
Published: April 2015

Long‐Term Mortality in Low‐Risk Adult LQTSIntroductionTo date, most risk stratification studies in long‐QT syndrome (LQTS) have focused on identification of high‐risk subjects. Current data on the long‐term clinical course of low‐risk adult LQTS patients are limited.Methods and ResultsPatients in this study were from the Rochester‐based LQTS Registry. We hypothesized that long‐term survival of LQT1‐2 patients with QTc <500 milliseconds and no cardiac symptoms before age 20 (n = 523) would be similar to that of their unaffected genotype‐negative family members (n = 1,134). Kaplan–Meier survival analysis and multivariate Cox proportional hazards regression models were used to evaluate the incidence and risk of all‐cause mortality in the study population. The low‐risk LQTS study group comprised 27% (523/1,919) of genetically confirmed LQTS Registry patients alive at age 20. The cumulative probability of all‐cause mortality between age 20 and 65 was similar in the low‐risk LQTS group and the genotype‐negative control group (4.3% and 4.4%, respectively at age 65; P = 0.49 for overall difference). Multivariate analysis showed no significant difference in the risk of all‐cause mortality between the 2 groups (HR = 0.89; 95% CI 0.33–2.43, P = 0.82). Consistent results were revealed in subgroup analyses in female and male LQTS patients and in patients with genetically identified LQT1 and LQT2 mutations.ConclusionsWe identified a sizeable proportion of low‐risk, adult LQTS patients with no cardiac symptoms before age 20 and QTc<500 milliseconds who had 45‐year survival similar to unaffected family members.
Aspirating during the intramuscular injection procedure: a systematic literature review
Authors: Sisson Helen 
Published: April 2015

Aims and objectivesTo review the available evidence on aspirating when administering intramuscular injections and suggest recommendations for practice.BackgroundThe process of aspiration has been ingrained in the intramuscular injection procedure, and whilst many policies no longer recommend this practice, it often continues to be taught and practiced. The result is a variation in this procedure not always consistent with an evidence‐based approach.DesignA systematic literature review.MethodsA systematic approach to searching the literature was undertaken using identified academic databases from inception to May 2014. Citation searching identified additional data sources. Six studies met the search criteria.ResultsThe majority of health professionals do not aspirate for the recommended 5–10 seconds. Administering an injection faster without aspiration is less painful than injecting slowly and aspirating. The main influences on the decision of whether or not to aspirate are based on what health professionals are taught and fear of injecting into a blood vessel.ConclusionsIn the paediatric vaccination setting, the practice of aspirating during the administration of an intramuscular injection is unnecessary and there is no clinical reason to suggest that these principles may not be applied when using the deltoid, ventrogluteal and vastus lateralis sites in other settings. Owing to its proximity to the gluteal artery, aspiration when using the dorsogluteal site is recommended. Nurses must be supported in all settings, by clear guidance which rejects traditional practice and facilitates evidence‐based practice.Relevance to clinical practiceEducators need to ensure that their knowledge is up to date so that what they teach is based on evidence. This may be facilitated via regular educational updates. Further research and subsequent guidance are needed to support evidence‐based practice in intramuscular injection techniques in all nursing settings.
Strategic Leadership and Leaders in Entrepreneurial Contexts: A Nexus for Innovation and Impact Missed?
Authors: Simsek Zeki , Jansen Justin J. P. , Minichilli Alessandro , Escriba‐Esteve Alejandro 
Published: April 2015

ABSTRACTResearch at the nexus of strategic leadership and entrepreneurial contexts has been encouraging, but some of the more innovative and impactful questions remain underexplored. The purpose of the Special Issue was to provide a forum for works that build on the constraints, challenges, characteristics, and other salient elements of entrepreneurial settings to advance theory and testing on strategic leadership effects, as well as enrich our understanding of firm behaviour and outcomes in entrepreneurial contexts. We first provide an overview and background of the Special Issue. We then provide a summary of the process and outcomes, including a synopsis of the accepted manuscripts. The discussion finally traces the implications of the Special Issue for future research directions on strategic leadership and leaders in entrepreneurial contexts.
Stenosing ureteritis in Henoch–Schönlein purpura: Report of two cases
Authors: Kasahara Katsuaki , Uemura Osamu , Nagai Takuhito , Yamakawa Satoshi , Nakano Masaru , Iwata Naoyuki 
Published: April 2015

AbstractStenosing ureteritis (SU), a rare complication of Henoch–Schönlein purpura (HSP), typically presents with severe symptoms. We report the cases of two HSP patients presenting with gross hematuria, blood clotting, and colicky flank pain, followed by purpura on the lower extremities. Early‐stage ultrasonography indicated hydronephrosis, thickened renal pelvic mucous membrane, and ureteral dilatation (UD), suggesting HSP complicated with SU. After early SU treatment with prednisolone, kidney function, thickened renal pelvic mucous membrane, and UD progressively normalized and the pain gradually disappeared. Regular ultrasonography of HSP patients from the onset of gross hematuria can be useful to detect early SU and facilitate conservative therapy with prednisolone. Diagnosis of SU can be easily missed by assuming HSP nephritis, particularly owing to the non‐specific symptoms. Common characteristics as well as treatment methods and prognosis of SU are given in the literature review.
Diffuse neonatal hemangiomatosis in a very low‐birthweight infant treated with erythropoietin
Authors: Okuno Takashi , Tokuriki Shuko , Yoshino Tomomi , Tanaka Nanae , Ohshima Yusei 
Published: April 2015

AbstractDiffuse neonatal hemangiomatosis (DNH) is a rare condition characterized by the concomitant development of multiple cutaneous infantile hemangiomas (IH) and visceral hemangiomas. Recently, an association between erythropoietin treatment and an increased incidence of infantile hemangioma was noted. A Japanese male infant was born via cesarean section at 27 weeks of gestation. Following the commencement of erythropoietin treatment for anemia of prematurity, he developed multiple cutaneous hemangiomas, high cardiac output heart failure and hepatomegaly. Abdominal imaging indicated comorbidity of diffuse infantile hepatic hemanigomas, resulting in the final diagnosis of DNH. The discontinuation of erythropoietin treatment and long‐term therapy with propranolol improved the hepatic lesions and cutaneous hemangiomas. The possibility of multiple organ involvement and the exacerbating effects of erythropoietin treatment should be considered in cases in which multiple cutaneous hemangiomas develop in preterm infants receiving erythropoietin treatment.
Diffuse alveolar hemorrhage secondary to ANCA‐associated vasculitis in a patient with Down syndrome
Authors: Hori Ikumi , Nakaseko Haruna , Kamei Michi , Nomura Takayasu , Iwata Naomi , Ito Yasuhiko , Saitoh Shinji 
Published: April 2015

AbstractDiffuse alveolar hemorrhage (DAH) is a rare disease characterized by dyspnea, cough, hemoptysis, and new alveolar infiltrates. Among the various underlying disorders, vasculitis is believed to play a significant role in the pathogenesis of DAH. Here we report the first case of a patient with Down syndrome who developed DAH secondary to anti‐neutrophil cytoplasmic antibody‐associated vasculitis. This case highlights the significance of vasculitis as well as pulmonary hypoplasia and vulnerability associated with Down syndrome in the development of DAH.