bluuebunny/crossref_metadata_2025_split huggingface dataset:
Knowledge and Preventive Practices of Abattoir Workers toward Bovine Tuberculosis in Wolaita Zone, Southern Ethiopia
Authors: Mathewos Mesfin , Atiso Tilahun , Fesseha Haben , Kebede Isayas Asefa 
Published: July 2024

ABSTRACT.
Bovine tuberculosis (bTB) is a zoonotic bacterial disease of animals that causes substantial economic losses in underdeveloped countries such as Ethiopia. A cross-sectional study was conducted from May 2021 to August 2021 in the Wolaita zone, southern Ethiopia using a designed questionnaire to assess risk, perception, and protective behavior against bTB. For this purpose, a total of 250 randomly chosen meat handlers working at six main, purposively selected abattoirs were interviewed, and the data were analyzed using STATA v. 13 software. Of the total participants interviewed, 37.0% (57/152) of the respondents strongly agreed that contracting bTB would prevent them from coming to work, whereas 32.4% (44/136) of them stayed in bed for an extended period. Knowledge-based analysis revealed that butcher house men were more aware than abattoir workers about factors related to the spread of bTB from animals to humans (73.3%), that healthy-looking meat contains bTB-causing pathogens (67.5%), and that consumption of contaminated meat can be a source of infection in humans (65.6%). These findings revealed that abattoir and butcher house employees are at higher risk of bTB exposure and a lack of understanding about the nature and transmission of the infection. Thus, abattoir and butcher house workers should be encouraged to pursue regular medical follow-ups and should be provided with better personal protective equipment.
Diagnostic Utility of Multiplex Polymerase Chain Reaction in Patients of Clinically Suspected Pure Neuritic Leprosy by Identifying Mycobacterium leprae in Skin Biopsy Samples and Nasal Swabs
Authors: Pathak Vinay Kumar , Sharma Apoorva , Sharma Ayush , Singh Itu , Kaur Manjot , Narang Tarun , Chatterjee Debajyoti , Pandey Pragati , Modi Manish , Dogra Sunil , Chhabra Seema 
Published: July 2024

ABSTRACT.
Pure neuritic leprosy (PNL) often remains underdiagnosed due to the lack of simple, reliable diagnostic tools to detect Mycobacterium leprae. This study aimed to investigate the utility of multiplex polymerase chain reaction (MPCR) in easily accessible and less invasive biopsy sites, including skin biopsy samples and nasal swabs (NSs), to detect M. leprae. A total of 30 (N = 30) clinically suspected and untreated patients with PNL were recruited. Nasal swabs and skin biopsy samples from the innervation territory of an “enlarged nerve” were collected. DNA was extracted and subjected to MPCR (targeting leprae-specific repetitive element [RLEP], 16S rRNA, and SodA genes) and RLEP-PCR (individual gene PCR). The PCR products were analyzed by 3% agarose gel electrophoresis. In 30 patients with clinically suspected PNL, 60% (N = 18) of skin biopsy samples and 53% (N = 16) of NSs were found positive for M. leprae DNA by MPCR, whereas only 23.3% (N = 7) of skin biopsy samples and 10% (N = 3) of NSs were found positive by RLEP-PCR. MPCR demonstrated a greater positivity rate than did RLEP-PCR for detection of M. leprae. Serologic positivity for anti-natural disaccharide-octyl conjugated with bovine serum albumin (ND-O-BSA) antibodies was 80% (16/20), including 35% (7/20) of PNL patients for which the skin MPCR was negative. Both serologic positivity and skin MPCR positivity were observed in 65% of patients (N = 20). Multiplex polymerase chain reaction is a useful tool for detection for M. leprae in skin biopsy samples and NSs in clinically suspected cases of PNL, with the added advantages of being less invasive and technically easier than nerve biopsy.
Resurgence of Dengue Virus Serotype 2: Findings from the 2023 Bangladesh Outbreak
Authors: Hasan Anamul , Zamil Md Fahad , Trina Afrida Tabassum , Biswas Rajat Sanker Roy , Kumkum Asifa , Ahmed Dilruba , Alam Mohammad Shafiul 
Published: July 2024

ABSTRACT.
Bangladesh experienced the largest and deadliest dengue outbreak in 2023, after the virus had reappeared in the country 2 decades earlier. A total of 1,705 people died in Bangladesh, representing the highest case fatality rate (0.5%) due to dengue in the world for that year. The severity of dengue infection is to some extent related to the emergence of new circulating serotypes. To identify the possible predominant serotype in 2023, the reverse transcription polymerase chain reaction-based identification technique was used on stored serum samples of suspected dengue patients during the period between July and December 2023. The overall result of molecular serotyping showed that dengue virus (DENV-2) reappeared as the predominant serotype (74.1%), followed by a moderate number of samples with DENV-1 (19.8%) and DENV-3 (6.1%), in 2023. However, DENV-1 was found to be dominant in a few rural areas of Cox’s Bazar districts. During the 2019 outbreak, DENV-3 was the dominant serotype, which seemed to be replaced by the DENV-2 serotype; this may have impacted the increased case fatality in 2023.
Revisão sistemática do manejo farmacológico na doença de Creutzfeldt-Jakob: ainda sem opções?
Authors: Pedrada Lucas Alves , Dantas Camille Pettene , Silva Junior Robson Waldeck , Silva Jassiara Soares da 
Published: July 2024

Introdução: A Doença de Creutzfeldt-Jakob (DCJ) é uma doença neurodegenerativa, caracterizada por provocar uma desordem cerebral com perda de memória e tremores. É de rápida evolução, e de forma inevitável, leva à morte do paciente. A doença de Creutzfeldt-Jakob (DCJ) é um tipo de Encefalopatia Espongiforme Transmissível (EET) que acomete os humanos. Objetivo: Realizar revisão sobre os avanços do manejo farmacológico da Doença de Creutzfeldt-Jakob. Materiais/sujeitos e métodos: A busca foi realizada na plataforma PUBMED em junho de 2024. Os descritores utilizados na pesquisa foram “Creutzfeldt-Jakob Syndrome" AND "Dementia" AND "Central Nervous System Infections" AND "Prion Diseases, todos definidos pelo Medical Subject Headings (MESH). Resultados e discussão: A Doença de Creutzfeldt-Jakob (conhecida como Doença da Vaca Louca) causa acometimento neurodegenerativo rápido, progressivo e fatal (Maioria morre dentro de 12 meses do início dos sintomas). É causada por partículas proteicas que sofreram mutação, sendo infecciosas e transmissíveis. Podem ser de 3 etiologias: esporádica (85% dos casos), adquirida (<1%) e genética (10-15%). Considerações Finais: Estudo caracterizado como ensaio clínico mostrou que a flupirtina pode reduzir, parcialmente, o declínio cognitivo comparado ao grupo controle. Desse modo, esta revisão destaca a necessidade de mais pesquisas para validar a eficácia de diferentes tratamentos farmacológicos para DCJ no futuro.
Comparative evaluation of Chakramarda ointment and Psoralin ointment along with Guduchi capsule in the management of KitibhaKushtha (Psoriasis)
Authors: Balpande Khushhali , Misar Sadhana , Nandal Praveen 
Published: July 2024

In Ayurveda skin disorders are mentioned under Kushtharogaadhikar and categorized into seven Mahakushthas and eleven Kshudrakushthas. Among all the Kshudrakushthas, Kitibhakushtha is one of the types. Sign & Symptoms of Kitibhakushtha are Kina Khara Sparsham (rough on touch), Shyava Varna (blackish brown color) and Kandu (itching). It is a Tridoshaja with the predominance of Vata-Kapha along with the involvement of Twak, Rakta, Mamsa and Lasika in the Samprapti. Nidanas of KitibhaKushtha are Aaharaj, Viharaj, Upsargaja and Krimija. KitibhaKushtha can be correlated with psoriasis due to similarities in symptoms. Aim and objectives: -Evaluation of comparative efficacy of Chakramarda ointment versus Psoralin ointment with capsule Guduchi internally in the management of Kitibha Kushtha (Psoriasis).
Material and Methods - This study comprises a total of 60 patients in which patients in Group A were treated with Chakramarda ointment once daily in the morning after bath and 2 Guduchi capsules 500mg thrice a day internally whereas patients in Group B were treated with Psoralin ointment once daily in the morning after bath and 2 Guduchi capsules 500 mg thrice a day internally for 30 days. Patients were assessed for subjective parameters like Kandu, Shyav Krishna Varna and Rookshata and objective parameter PASI scale. Result – Significant improvement was observed in Subjective and Objective parameters. Conclusion- Chakramarda ointment is as efficacious as Psoralin ointment in the treatment of KitibhaKushtha. Hence Kitibha Kushtha can be effectively managed with Chakramarda ointment.
Inner Areas and Green Economy in Campania Region: The Carditello Royal Borbonic Site Case Study
Authors: Bertini Antonio , Vitolo Tiziana 
Published: July 2024

In Italy, within the 'National Strategy on Inland Areas', 'belt areas', 'peripheral areas' and 'ultra-peripheral areas' have emerged and been recognised for the first time since 2013, as well as 'intermediate areas'. The area presented in the paper is atypical, although it presents some recurring characteristics in other intermediate areas close to Italian metropolitan areas. It is an area near of Naples, in the region of Campania, which gravitates around the Royal Bourbon Site of Carditello with a past of considerable historical interest and an unfortunate recent past, which has led it to be in a particularly disadvantaged condition. The paper deals with a topic with little reference literature, at least as far as the Italian reality is concerned; mixed areas, partly 'intermediate' and partly 'Belt'. After a careful Swot analysis, adapted to the territorial context of the area under consideration, focusing on its considerable potential, pointing out some problematic nodes and indicating ways to overcome them, seizing and creating some opportunities for possible sustainable development, the paper proposes a perspective scenario that aims at the sustainable enhancement of the area.

Received: 4 December 2023 | Revised: 22 May 2024 | Accepted: 1 July 2024

Conflicts of Interest
The authors declare that they have no conflicts of interest to this work.

Data Availability Statement
The data that support the findings of this study are openly available in IDEHA. http://www.ponricerca.gov.it/comunicazione/example-projects/industrial-research-and-experimental-development-projects-in-the-12-specialization-areas/ideha/.

Author Contribution Statement
Antonio Bertini: Conceptualization, Methodology, Software, Validation, Formal analysis, Resources, Data curation, Project administration, Funding acquisition. Tiziana Vitolo: Conceptualization, Methodology, Validation, Formal analysis, Investigation, Resources, Data curation, Writing - original draft, Writing - review & editing, Visualization, Supervision, Project administration, Funding acquisition.
PRÁTICAS DE LETRAMENTO URBANÍSTICO COM ESTUDANTES DO ENSINO MÉDIO PARA UM MUNDO MAIS SUSTENTÁVEL
Authors: Aparecida Messias Guilherme Regina , Jacob Martins Clovis 
Published: July 2024

Este trabalho teve como objetivo discutir a importância de identificar e reconhecer a cidade como um texto a ser lido, interpretado e aprendido por estudantes do ensino médio e participantes do curso de extensão Produções Textuais e Interculturais da Universidade Estadual de Ponta Grossa (UEPG). Para alcançar tal objetivo estabeleceu-se uma sequência didática e optou-se pela Pesquisa-ação como um meio para captar e gerar dados a serem interpretados. As práticas de letramento contribuíram significativamente para que os estudantes compreendessem a relevância e a importância da cidade na sua formação.
Palavras-chave: Letramento Urbanístico; cidade; educação.
Ethnomedical Perspectives on Visha Dravyas – A Review
Authors: B Soubhaghyalaxmi 
Published: July 2024

Introduction: Ethnomedicine, the study of traditional medical practices used by various ethnic groups, often incorporates the use of “Visha Dravyas“ in therapeutic contexts. This review delves into the ethnomedical perspectives on Visha Dravyas, highlighting their historical and contemporary applications, and therapeutic benefits within traditional medical systems such as Ayurveda and indigenous healing practices. Visha Dravyas, despite their inherent toxicity, have been meticulously utilized for their potent medicinal properties, offering treatments for a range of ailments. This dual nature — being both toxic and therapeutic — underscores the sophistication of traditional knowledge systems in balancing harm and healing. Materials and Methods: The review examines key poisonous plants and their pharmacological uses in different regions of India and the world, supported by both traditional texts and modern scientific studies. In addition, the review addresses the cultural and ritualistic aspects of Visha Dravyas, emphasizing the holistic approach of ethnomedical practices that integrate physical, spiritual, and environmental health. Results: This study aims to provide a comprehensive understanding of the role of Visha Dravyas in ethnomedicine. It underscores the importance of preserving traditional knowledge and promoting interdisciplinary research to unlock the full potential of these potent natural resources. Discussion: The findings highlight the need for a nuanced approach to integrating traditional and modern medical practices, ensuring safety and efficacy in the use of Visha Dravyas for future health-care innovations. Conclusion: Review concluded that the use of ethnomedicinal plants increased with elevation due to limited alternative options and market accessibility. Almost all plants contain active components that can be effective against diseases, but certain plants despite being poisonous possess valuable medicinal use.
IMPLEMENTASI METODE AHP DAN SAW DALAM PEMILIHAN GURU TERBAIK DI SMK PLUS MUNIRUL ARIFIN NW PRAYA
Authors: Khotimah Husnul , Zaen Mohammad Taufan Asri , Imtihan Khairul 
Published: July 2024

SMK Plus Munirul Arifin NW Praya merupakan sebuah lembaga pendidikan di bawah naungan Yayasan Munirul Arifin NW praya yang berlokasi di kabupaten Lombok tengah. SMK Plus Munirul Arifin NW Praya merupakan satuan pendidikan formal yang memiliki peran untuk meningkatkan mutu pendidikan bagi para peserta didiknya, sehingga peran guru sangatlah penting untuk mencapai tujuan tersebut. Oleh karena itu kualitas guru juga sangat mempengaruhi tercapainya pendidikan yang berkualitas bagi peserta didik. Untuk meningkatkan kinerja guru, kepala sekolah ingin memberikan apresiasi berupa penghargaan kepada guru yang memiliki kinerja terbaik di SMK Plus Munirul Arifin NW Praya. Penelitian ini menggunakan gabungan dua metode yaitu metode AHP dan SAW, dimana metode AHP digunakan untuk penentuan bobot dari masing- masing kriteria dan metode SAW digunakan untuk penentuan solusi dari permasalahan yaitu menentukan guru tebaik dengan perangkingan. Pada penentuan bobot kriteria menggunakan metode AHP di menghasilkan bobot masing-masing kriteria yaitu Loyalitas sebesar 43%, Kedisiplinan 21%, Pedagodik 12%, Kepribadian 20%, dan sosial sebanyak 4%.kemudian hasil dari perangkingan yang dilakukan dengan metode SAW menghasilkan peringkat pertama di dapatkan oleh Alternatif 1 atas nama Amruzziyad dengan jumlah nilai 0,96.
IDEIAS PARA O BRASIL AJUDAR A ADIAR O FIM DO MUNDO
Authors: Andrade Filho Milton Pereira de 
Published: July 2024

O presente artigo tem como intuito analisar a obra “Ideias para adiar o fim do mundo.” (KRENAK, Ailton) e ponderar se a atuação da Política Ambiental do Governo Federal segue na mesma direção preservacionista apontada pelo livro ou se anda em antagônico caminho. A análise nos faz refletir sobre a importância da preservação dos biomas uma vez que avanços em pesquisas ambientais demonstram que as queimadas e o desmatamento florestal afetam diretamente o aquecimento global. Apesar da preservação do meio ambiente ser garantia expressamente inserida na Constituição Federal Brasileira, a contemporânea administração ambiental nacional demonstra um sério descaso com o tema, com um verdadeiro desaparelhamento dos órgãos ambientais, o que se verifica nos números de queimadas recordistas comumente verificados nos últimos, afrontando acordos firmados internacionalmente em descompasso com a Bioética e o Biodireito. Tal posicionamento anda em direção contrária à posição da obra “Ideias para adiar o fim do mundo.” (KRENAK, Ailton) que busca “humanizar” elementos a natureza que, em sendo assim, com um olhar mais detalhado, estariam sujeitos a direitos, e deveres, a serem preservados e defendidos. Conhecido pensador da atualidade, o indígena Ailton Krenak luta pelos direitos dos povos indígenas, e, no livro em comento, atribui às modernas civilizações o papel de predadores do meio ambiente e analisam se há humanidade em atos de autodestruição, com a exploração excessiva da natureza, chegando a exaustão dos biomas. O Livro foi pensado após uma viagem à Lisboa, baseado em entrevistas e em palestras por ele ministradas. Analisando a obra, verificamos a importância do cumprimento de metas ambientais, porém, como demonstrado, objetivos como a redução de resíduos não são prioridades da atual gestão ambiental brasileira, que age em inobservância ao que preceitua a Constituição Federal Brasileira. Entre outras causas, a ausência do Estado e o desaparelhamento realizado pelo Governo Federal nos órgãos ambientais, estão diretamente ligadas ao aumento de queimadas contribuindo com a destruição dos biomas.
Гайана в фокусе латиноамериканской политики администрации Дж. Байдена
Authors: Требух Александр Дмитриевич 
Published: July 2024

Американо-гайанские отношения остаются малоизученными в отечественной и зарубежной научной литературе. В то же время динамика региональной системы и рост влияния стран Латино-Карибской Америки в контексте американо-китайского соперничества определяют актуальность и необходимость уточнения существующего статуса США в этом регионе. В данной работе автором предпринимается попытка охарактеризовать американо-гайанские отношения и оценить роль Гайаны для региональной стратегии Вашингтона на современном этапе при администрации Дж. Байдена. Автор использует сравнительный метод, характеризуя внешнеполитические шаги США в отношении Гайаны при администрациях Д. Трампа и Дж. Байдена. Кроме того, автор пытается проанализировать и определить значение нематериальных факторов и идей, влияющих как на внешнеполитическую стратегию администрации Дж. Байдена, так и на восприятие этими странами друг друга. Автор приходит к выводу, что интенсификация американо-гайанских отношений при администрации Дж. Байдена окажет положительное влияние на обе страны, но в долгосрочной перспективе это не приведет к стратегическому партнерству. Несмотря на возможное снижение внимания к региону в целом с приходом республиканской администрации в 2025-м году, Соединенные Штаты Америки будут наращивать свое экономическое и военное присутствие в Гайане ввиду резко возросшей экономико-стратегической значимости страны.
ФинансированиеРабота выполнена без внешних источников финансирования.
Проблема политической коммуникации в условиях новых медиа
Authors: Шукюров Алексей Тофикович 
Published: July 2024

Новые медиа стали новым общественно-политическим пространством для обсуждения, а зачастую и для ожесточенных споров о политических и социальных вопросах. Цифровые медиаисточники, такие как социальные сети или информационные сайты, занимают центральное место в ландшафте политических коммуникаций. Это подтверждает возрастающую роль гражданина в политике и меняющуюся динамику политической коммуникации в условиях этих трансформаций. Растущий радиус новых медиа можно наблюдать как в развитых, так и в развивающихся странах. Пандемию COVID-19 можно рассматривать триггером этих событий – возникшее в результате более широкое использование виртуальных встреч для политической коммуникации стало постоянным. Революция новых медиатехнологий изменила и модель политической коммуникации, которая породила проблемы современному обществу. Информация обрушивается потоком на граждан, в результате снижается эффективность ее оценки, анализа и интерпретации. Информационная перегрузка стала вызовом человечеству. Возникающие последствия информационно-политической перегрузки требуют применения мер противодействия, которые воздействуют на причины информационной перегрузки.

ФинансированиеРабота выполнена без внешних источников финансирования.
DYNAMIC MINING DESIGN AND PLANNING MODE
Authors: Сытенков В.Н. 
Published: July 2024

В статье рассмотрен динамичный режим проектирования и планирования горных работ, связанный с изменяющимися во времени и пространстве качественными и количественными характеристиками добываемого полезного ископаемого. Основная задача, решаемая при составлении ТЭП и планов развития освоения объекта, обусловлена последовательным смещением технико-экономической границы выемки запасов в сторону уменьшения их промышленного содержания.
The article considers the dynamic mode of mining design and planning associated with the qualitative and quantitative characteristics of the extracted mineral changing in time and space. The main task to be solved in the preparation of TEP and development plans for the development of the facility is due to the consistent shift of the technical and economic boundary of the extraction of reserves towards a decrease in their industrial content.
ASSESSMENT OF ENGINEERING AND GEOLOGICAL PROCESSES IN THE EXPLORATION OF ORE DEPOSITS IN CENTRAL KYZYLKUM
Authors: Усманов С.Р. , Ахунжанов А.М. , Курбанов Э.Ш. 
Published: July 2024

Рассматриваются инженерно-геологические процессы при открытой разработке и разведке месторождений шахтным способом, где развиваются неблагоприятные процессы и явления: обрушения, вывалы и выветривание пород на откосах бортов карьеров и в подземных горных выработках, наиболее характерные для переслаивающихся дислоцированных сланцевых толщ. По инженерно-геологическим условиям отработки месторождения делятся на три группы: Тамдытау, Ауминза-Бельтау и Ауминзатау. Дается причина и характеристика развития деформационных процессов в зависимости от геолого-структурных, геологических, а также климатических факторов, предопределяющих развитие деформационных процессов.
The article considers engineering-geological processes during open-pit mining and exploration by the mine method, in which unfavorable processes and phenomena develop: collapse, fallout and weathering of rocks on the slopes of the sides of quarries and in underground mine workings, which is most characteristic of interbedded dislocated shale strata. According to the engineering and geological conditions of mining, the deposit is divided into three groups: Tamdytau, Auminza-Beltau and Auminzatau. The reason and characteristics of the development of deformation processes are given, depending on the geological-structural, geological, and climatic factors that predetermine the development of the formation of deformation processes.