bluuebunny/crossref_metadata_2025_split huggingface dataset:
Australian mental health consumers' and carers' experiences of community pharmacy service
Authors: Knox Kathy , Kelly Fiona , Mey Amary , Hattingh Laetitia , Fowler Jane L. , Wheeler Amanda J. 
Published: March 2014

AbstractBackgroundMany Australians with anxiety or depression experience issues accessing pharmacological treatment even though community pharmacies are remunerated to supply subsidized medicines and provide medicine management services.ObjectiveTo obtain insight into the quality of community pharmacy services from the perspectives of mental health consumers and carers.MethodsA computer‐assisted telephone interview was used to gauge perceptions of pharmacy service using frameworks of service quality and patient‐centred care. A convenience sample of 210 consumers and carers from three Australian states completed an interview comprising rating scales, multiple choice checklists and open‐ended questions to explore their experience of pharmacy services.ResultsParticipants were consumers experiencing on‐going mental health condition(s) (n = 172), carers for someone who experienced a mental health condition (n = 15) or both (n = 23). For 60% of participants, medicines were dispensed within ten minutes of arriving at the pharmacy, and 36% received verbal advice. The majority of participants were not asked by pharmacy staff whether they experienced side‐effects, and 60% reported rarely or never receiving written medicine information. However, the majority of participants reported that their expectations were met despite the absence of such services. Qualitative data showed that participants valued high‐quality services that reflected patient‐centred care, and they were inclined to engage with these services particularly if they perceived them as surpassing basic expectations.Discussion and conclusionsParticipants clearly valued high‐quality pharmacy service yet did not routinely expect it. When service exceeded expectations, community pharmacies were viewed as safe health‐care spaces to seek advice on mental health and well‐being. This study has positive implications for the role of pharmacists.
Patient participation in clinical encounters: a systematic review to identify self‐report measures
Authors: Mavis Brian , Holmes Rovner Margaret , Jorgenson Sarah , Coffey John , Anand Nandita , Bulica Emi , Gaulden Carolyn Marie , Peacock Jacob , Ernst Alycia 
Published: March 2014

AbstractBackgroundThere is evidence suggesting that active participation of patients in their health care can improve the quality of care and decrease health‐care costs. Further, patient reports of their health‐care experience are increasingly used to monitor health‐care quality.ObjectiveThis paper describes a systematic review of peer‐reviewed studies to identify measures of patients' active participation in their encounters with health‐care providers.MethodsA systematic literature review was conducted for publications indexed from 1975 to 2011. Of interest were self‐reported measures of patient participation that were not limited to a specific health concern. All abstracts were reviewed independently by two authors, and the full paper was considered for those meeting inclusion criteria.Main ResultsFrom a review of 4528 citations, ten measures were identified. The approaches to development of the measures varied considerably, as did their study samples and their psychometric quality.DiscussionThese measures represented three conceptual frameworks: empowerment and self‐efficacy, therapeutic alliance, and consumerism/satisfaction. They provide a more comprehensive perspective of patients' experiences of their provider encounters, and a better understanding patient behaviour enhanced the quality of health‐care delivery or improved health outcomes. These measures underscore the continuing challenge of defining patient participation and the multiple theoretical approaches that underlie this form of patient behaviour.ConclusionsCurrent interest in quality‐related physician report cards gives significant weight to patients' self‐reported experiences as one dimension of physician performance. It is critical to identify the specific focus and quality of measures selected for this and research purposes.
The Canine Orthopedic Index. Step 3: Responsiveness Testing
Authors: Brown Dorothy Cimino 
Published: March 2014

ObjectiveTo determine whether the Canine Orthopedic Index (COI) can detect changes in dogs with osteoarthritis (OA) treated with either non‐steroidal anti‐inflammatory drugs (NSAID) or placebo.Study DesignDouble blind randomized placebo controlled trial.AnimalsDogs (n = 80) with OA.MethodsOwners completed the COI on Day 0. Dogs were administered either carprofen or placebo on days 1 through 14. Owners completed the COI again on Day 14. The change in total instrument, stiffness, gait, function, and quality of life scores were assessed between groups.ResultsDogs administered carprofen had significant decreases in the total instrument score (P = .002) as well as 3 of the 4 factor scores compared to dogs treated with placebo (stiffness scoreP = .015; gait scoreP = .001; and function score = 0.008). The change in quality of life score was not significantly different between carprofen and placebo treated dogs (P = .124).ConclusionsThe COI delivered the decreases in total instrument, stiffness, gait, and function scores that one would expect in dogs with OA treated with an NSAID compared with placebo administration. In this cohort of dogs, the quality of life score was not sensitive to the changes associated with NSAID administration.
Initial Experience With rhBMP‐2 Delivered in a Compressive Resistant Matrix for Mandibular Reconstruction in 5 Dogs
Authors: Boudrieau Randy J. 
Published: March 2014

ObjectiveTo document cumulative initial experience and long‐term follow‐up of the use of rhBMP‐2/CRM for reconstruction of large mandibular defects (≥5 cm) in dogs.Study DesignRetrospective case series.AnimalsDogs (n = 5).MethodsMedical records (October 1999–April 2011) of dogs that had mandibular reconstruction for defects/resections of ≥5 cm using rhBMP‐2/CRM were reviewed. Signalment, preoperative assessment/rationale for mandibular reconstruction, surgical methods, postoperative assessment of the reconstruction (evaluation of occlusion), and complications were recorded. A definitive histologic diagnosis was obtained in dogs that had mandibular resection for mass removal. Long‐term complications were determined. A minimum time frame of 2‐year in‐hospital follow‐up was required for case inclusion.ResultsMandibular reconstruction was successfully performed in all dogs' defects where gaps of 5–9 cm were bridged. Surgical reconstruction rapidly restored cosmetic appearance and function. All dogs healed with new bone formation across the gap. New bone formation was present within the defects as early as 2 weeks after surgery based on palpation, and new bone formation bridging the gap was documented radiographically by 16 weeks. Minor complications occurred in all dogs in the early postoperative period, and included early firm swelling and gingival dehiscence in 1 dog; late plate exposure in 3 dogs; and exuberant/cystic bone formation in 2 dogs (related to concentration/formulation of rhBMP‐2/CRM). Two dogs had minor long‐term complications of late plate exposure and a non‐vital canine tooth; the plates and the affected canine tooth were removed. Long‐term in‐hospital follow‐up was 5.3 years (range, 2–12.5 years); further long‐term telephone follow‐up was 6.3 years (range, 2–12.5 years). All owners were pleased with the outcome and would repeat the surgery again under similar circumstances.ConclusionThe efficacy and success of this mandibular reconstruction technique, using rhBMP‐2/CRM with plate fixation, was demonstrated with bridging of large mandibular defects regardless of the underlying cause, and with excellent cosmetic and functional results. Complications were common, but considered minor and easily treated. The complications encountered revealed the importance of tailoring the use of BMPs and fixation methods to this specific anatomic location and indication.
Positive peer pressure: Priming member prototypicality can decrease undergraduate drinking
Authors: Goode Chris , Balzarini Rhonda H. , Smith Heather J. 
Published: March 2014

AbstractIn two field experiments, we manipulated the extent to which sorority members viewed themselves as prototypical group members before they learned social norm information. In Study 1 (n = 109), participants who learned that they closely matched the ideal group member's personality intended to drink less alcohol after reading about related group norms. In Study 2 (n = 155), participants primed to think of themselves as ideal group members reported drinking less alcohol in comparison to participants primed to think of themselves as unique individuals. Participants who heard a descriptive norm presentation reported drinking less alcohol in comparison to participants who heard injunctive or combined norm presentations. If speakers prime group member prototypicality before delivering normative information, their message can be more effective.
Has Web 2.0 revitalized informal learning? The relationship between Web 2.0 and informal learning
Authors: Song D. , Lee J. 
Published: March 2014

AbstractLearning is becoming increasingly self‐directed and often occurs away from schools and other formal educational settings. The development of a myriad of new technologies for learning has enabled people to learn anywhere and anytime. Web 2.0 technology allows researchers to shed a new light on the importance and prevalence of informal learning. However, there are few empirical studies that support the claim that this technology facilitates informal learning. The present study investigates the relationship between Web 2.0 levels and the evaluation of informal learning websites. For this purpose, 287 informal learning websites were selected and their Web 2.0 levels were rated based upon eight criteria proposed in the Web 2.0 exploratory literature. In addition, previously examined informal learning evaluation results were employed. The results showed that current informal learning websites have moderately adopted the most heavily promoted features of Web 2.0. Correlation analyses showed a positive relationship between Web 2.0 features and informal learning website ratings. The implications for the relationship and internal correlations of variables were summarized and discussed.
The effect of story grammars on creative self‐efficacy and digital storytelling
Authors: Liu C‐C. , Wu L.Y. , Chen Z‐M. , Tsai C‐C. , Lin H‐M. 
Published: March 2014

AbstractPrevious studies have proposed that the grammars may serve as a rule‐based scaffolding to facilitate story comprehension in storytelling activities. Such scaffoldings may inform students of crucial story elements and possible transitions among different elements. However, how these scaffoldings may influence story creation/writing activities is still not very clear. This study aims to understand and explore the relationship among rule‐based scaffoldings, creative self‐efficacy and storytelling products. By gathering the stories developed by 53 sixth graders and their creative self‐efficacy in a quasi‐experiment setting, this study investigated whether providing these rule‐based scaffoldings may influence their performance and creative self‐efficacy. The results of this study indicated that with these rule‐based scaffoldings, students produced better storytelling products in terms of content quality. However, the presence of story grammar rules also limited the students' freedom of creative thinking, and thus reduced the creative self‐efficacy level at the early stage of learning to create stories. Such findings support that the rule‐based scaffolding may be more helpful in facilitating storytelling in the idea exploration phase than in the generation phase. Educators may need to be cautious regarding the time point at which rule‐based scaffoldings would be most effectively integrated with learning activities.
Interactive whiteboard and virtual learning environment combined: effects on mathematics education
Authors: Heemskerk I. , Kuiper E. , Meijer J. 
Published: March 2014

AbstractThis study reports on the effects of the combined use of an interactive whiteboard (IWB) and a virtual learning environment (VLE) on mathematics performance and motivation. Lessons taught with an IWB were made available on the VLE, so that they could be consulted regardless of time and place. Students' mathematics performance was monitored during one school year and their motivation for mathematics was followed for 3 years. There was no relation between frequency of being taught with an IWB and mathematics performance. However, students' motivation for mathematics appeared to be positively related to the combination of lessons made for the IWB and availability of these lessons on the VLE. This availability was also the main reason for students' appreciation of the VLE. Students appeared to use the VLE mostly to prepare for tests and examinations.
Epithelial Attachment and Downgrowth on Dental Implant Abutments—A Comprehensive Review
Authors: Iglhaut Gerhard , Schwarz Frank , Winter Robert R. , Mihatovic Ilja , Stimmelmayr Michael , Schliephake Henning 
Published: March 2014

AbstractThe soft tissues around dental implants are enlarged compared with the gingiva because of the longer junctional epithelium and the hemidesmosonal attachments are fewer, suggestive of a poorer quality attachment. Inflammatory infiltrates caused by bacterial colonization of the implant‐abutment interface are thought to be one of the factors causing epithelial downgrowth and subsequent peri‐implant bone loss. Gold alloys and dental ceramics as well as the contamination of the implant surface with amino alcohols, appear to promote epithelial downgrowth. Physical manipulaton of the abutment surfaces, including concave abutment designs, platform switching, and microgrooved surfaces are believed to inhibit epithelial downgrowth and minimizes bone loss at the implant shoulder. This paper reviews the factors that are believed to influence the migration of epithelial attachment the dental implant and abutment surfaces. Exploration of innovative computer‐aided design/computer‐aided manufacturing‐based concepts such as “one abutment—one time” and their effect on epithelial downgrowth are discussed.Clinical SignificanceBased on the review of current literature, the authors recommend inserting definitive abutments at the time of surgical uncovering. To implement this concept, registration of the implant position should to be taken at the time of surgical implant placement.
Circumstances and Contributing Causes of Fall Deaths among Persons Aged 65 and Older: United States, 2010
Authors: Stevens Judy A. , Rudd Rose A. 
Published: March 2014

ObjectivesTo determine whether the increasing fall death rate among people aged 65 and older is due in part to temporal changes in recording the underlying cause of death.DesignAnalyses of multiple cause of death data using the online Centers for Disease Control and Prevention Wide‐ranging ON‐line Data for Epidemiologic Research system, which uses the National Center for Health Statistics' Multiple Cause of Death data set.SettingUnited States, 1999 to 2010.ParticipantsPeople aged 65 and older with a fall listed on their death record as the underlying or a contributing cause of death.MeasurementsCircumstances and contributing causes off all deaths—records listing International Classification of Diseases, Tenth Revision, codes W00 to W19 as the underlying cause of death—and underlying causes for records with falls as a contributing cause were examined. Joinpoint regression analysis was used to assess trends in the proportion of fall and fall‐associated deaths to total deaths for 1999 to 2010.ResultsIn 2010, there were 21,649 fall deaths and 5,402 fall‐associated deaths among people aged 65 and older; 48.7% of fall deaths involved a head injury. Approximately half the fall death records included diseases of the circulatory system as contributing causes. From 1999 to 2010, there was a trend toward more‐specific reporting of falls circumstances, although total deaths remained unchanged. The proportion of fall deaths to total deaths increased 114.3%, and that of fall‐associated deaths to total deaths increased 43.1%.ConclusionThe reasons behind the increasing older adult fall death rate deserve further investigation. Possible contributing factors include changing trends in underlying chronic diseases and better reporting of falls as the underlying cause of death.
Posterior scissors‐bite: masticatory jaw movement and muscle activity
Authors: Tomonari H. , Kubota T. , Yagi T. , Kuninori T. , Kitashima F. , Uehara S. , Miyawaki S. 
Published: March 2014

SummaryScissors‐bite is a malocclusion characterised by buccal inclination or buccoversion of the maxillary posterior tooth and/or linguoclination or linguoversion of the mandibular posterior tooth. This type of malocclusion causes reduced contact of the occlusal surfaces and can cause excessive vertical overlapping of the posterior teeth. This case–control study is the first to evaluate both masticatory jaw movement and masseter and temporalis muscle activity in patients with unilateral posterior scissors‐bite. Jaw movement variables and surface electromyography data were recorded in 30 adult patients with unilateral posterior scissors‐bite malocclusion and 18 subjects with normal occlusion in a case–control study. The chewing pattern on the scissors‐bite side significantly differed from that of the non‐scissors‐bite side in the patients and of the right side in the normal subjects. These differences included a narrower chewing pattern (closing angle, P < 0·01; cycle width, P < 0·01), a longer closing duration (P < 0·05), a slower closing velocity (P < 0·01) and lower activities of both the temporalis (P < 0·05) and the masseter (P < 0·05) muscles on the working side. In 96% of the patients with unilateral posterior scissors‐bite, the preferred chewing side was the non‐scissors‐bite side (P = 0·005). These findings suggest that scissors‐bite malocclusion is associated with the masticatory chewing pattern and muscle activity, involving the choice of the preferred chewing side in patients with unilateral posterior scissors‐bite.
Paired Preference Tests with Reversed Hidden Demand Characteristics
Authors: Xia Yixun , Rivera‐Quintero Alondra , Calderon Eduardo , Zhong Fang , O'Mahony Michael 
Published: March 2014

AbstractTo gain insight into the proportion of consumers who respond to extraneous factors in the paired preference testing situation, rather than the sensory properties of products being assessed, “placebo” preference tests with putatively identical products are used. One use is as a tool to select consumers who ignore extraneous factors and are thus suitable for use in preference tests, where experimenters wish to have confidence that consumers are ignoring extraneous factors and responding only to the sensory attributes of the products being tested. Yet, selecting such consumers tends often to reduce the sample size to approximately 20–35% of its original, which is unacceptably low. The protocol used in this study employed unusual instructions and questions to reverse the hidden demand characteristics of the test, so that the sample size was only reduced to 80–90% of its original.Practical ApplicationsPaired preference tests are part of the battery of tests used for measuring food acceptance. Although, when used casually, the test is simple; when used for a formal assessment of acceptance, there are problems that must be addressed. One such problem is the tendency of consumers to respond with preferences, even when the stimuli are putatively identical. Such a bias has the potential to produce an overestimation of preferences, when products are being assessed by paired preference protocols. Accordingly, research into this phenomenon is worthwhile, so that more valid and reliable tests can be developed.
Screening ofChinese cabbage mutants produced by60Co γ‐ray mutagenesis of isolated microspore cultures
Authors: Huang Shengnan , Liu Zhiyong , Li Danyang , Yao Runpeng , Meng Qian , Feng Hui 
Published: March 2014

AbstractSince the release of theChinese cabbage genome sequence, increasing interest has focused on the functional analysis of unidentified genes inChinese cabbage. Mutant analysis forms the basis of functional genomics research. To produce a variety ofChinese cabbage mutants in the same genetic background, buds containing late uninucleate spores from a doubled haploid line of theChinese cabbage variety ‘Fukuda 50’ were irradiated with60Co γ‐rays at doses of 20, 40 and 60 Gy. Then, the treated microspores were isolated and cultured. A total of 492 putativeM0mutants were isolated from 1483 regenerated plants. Of these, sixM1mutants were verified; the mutant frequency was 0.41%. These mutants comprise a mutant library that includes one plant shape mutant, two flower mutants and three male sterile mutants. Pollen viability detection andDNAflow cytometry were used to determine the ploidy of the regenerated plants. Some of the mutants isolated in this study may be useful forChinese cabbage breeding and functional genomics research.
Immunolocalization of the Cholesterol Transporters ABCA1 and ABCG1 in Canine Reproductive Tract Tissues and Spermatozoa
Authors: Palme N , Becher AC , Merkl M , Glösmann M , Aurich C , Schäfer‐Somi S 
Published: March 2014

ContentsThe mammalian sperm membrane undergoes cholesterol efflux during maturation and fertilization. Although ATP‐binding cassette (ABC) transporters are known to transport cholesterol through cell membranes in other organs, their presence in canine testis, epididymis and sperm has not been proven to date. Hence, the aim of the present study was to localize the ABC transporters ABCA1 and ABCG1 in canine testicular and epididymidal tissue as well as in spermatozoa membranes. To this end, semen samples from 12 dogs as well as testicles and epididymides of four young and healthy dogs were prepared for immunohistochemistry, respectively. Capacitation and acrosome reaction (AR) were induced in aliquots of the semen samples before immunostaining to assess changes in the expression of ABCA1 and ABCG1. Evaluation by confocal microscopy revealed the presence of both ABCA1 and ABCG1 in canine testicles and of ABCA1 in the epididymides. In spermatozoa, only ABCA1 immunoreactivity was detected, mainly in the region of the acrosome and midpiece. After induction of capacitation, ABCA1 signal persisted in the acrosome but disappeared after AR, indicating a loss of ABCA1 with the loss of the acrosome. We conclude that ABCA1 and ABCG1 are expressed in canine testis, whereas only ABCA1 is expressed in epididymis and spermatozoa membrane, both transporters probably contributing to the regulation of membrane cholesterol content.
High‐Mobility Group Box 1 Inhibition Alleviates Lupus‐Like Disease in BXSB Mice
Authors: Zhang C. , Li C. , Jia S. , Yao P. , Yang Q. , Zhang Y. 
Published: March 2014

AbstractHigh‐mobility group box 1 protein (HMGB1), a ubiquitous nuclear DNA‐binding protein, functions as a potent proinflammatory factor. In this study, we evaluated the effects of HMGB1 inhibition on murine lupus using the lupus‐prone model. We treated male BXSB mice with neutralizing anti‐HMGB1 monoclonal antibody (HMGB1 mAb) from age 16 weeks to 26 weeks. The control group received the same amount of control IgG. Lupus‐prone male BXSB mice treated with HMGB1mAb showed attenuated proteinuria, glomerulonephritis, circulating anti‐dsDNA and immune complex deposition. Levels of serum IL‐1β, IL‐6, IL‐17 and IL‐18 were also significantly decreased by administration of HMGB1mAb in lupus‐prone BXSB mice. HMGB1mAb treatment also decreased the caspase‐1 activity in the kidneys of BXSB mice and reduced the mouse mortality. Our study supports that HMGB1 inhibition alleviates lupus‐like disease in BXSB mice and might be a potential treatment option for human SLE.