bluuebunny/crossref_metadata_2025_split huggingface dataset:
Novel phase‐change PDA‐Ni@GNS/CNF‐C/SA/PEG composites with ultrahigh shape stability and latent heat as thermal management material for microelectronic devices
Authors: Wang Xiaohong , Yang Bin , Zhang Yue , Yang Yuqing , Lu Huijie , Wang Hao , Wang Ziyi , Qian Jiasheng , Xia Ru , Jia Ning , Ke Yuchao 
Published: July 2024

AbstractPhase‐change materials (PCMs) have become a hot spot in the development of modern thermal management materials because of their absorbing and releasing heat while keeping the temperature constant during phase change process. However, their relatively low thermal conductivity (TC) considerably restricts their further application. In this work, graphene nanosheets (GNS) were initially nickel‐plated to increase the contact area between adjacent GNS (in the form of Ni@GNS) by constructing a “point‐surface” structure. Then, the prepared Ni@GNS was coated with polydopamine (PDA) to prepare PDA‐Ni@GNS, which helped to effectively reduce the interface thermal resistance (ITR) between the filler and the matrix, and also made the prepared filler more easily dispersed in the polymer matrix. By constructing well‐defined three‐dimensional (3D) thermally conductive pathways in the matrix, the PCMs exhibited excellent TC and effectively prevented the leakage of polyethylene glycol (PEG) even at low filler loading. The results of thermogravimetry (TG), differential scanning calorimeter (DSC), and cyclic DSC tests jointly showed that the PDA‐Ni@GNS/CNF‐C/SA/PEG PCMs displayed excellent thermal storage properties, high latent heat as well as good cyclic thermal stability. The present study provides a facile way of preparing PEG‐based PCMs, which are applicable in thermal management area.
Dry reforming of methane at high temperature and elevated pressure over nickel spinellized powder catalyst and pellets prepared from a metallurgical residue
Authors: Malik Muhammad Irfan , Rouabah Maroua , Abatzoglou Nicolas , Achouri Inès Esma 
Published: July 2024

AbstractThe coke deposition on catalysts is a significant problem in the dry reforming of methane at elevated pressures. Understanding and controlling the mechanisms of such deposition is essential in developing a techno‐economically viable industrial application for the production of synthesis gas and/or hydrogen. The patent‐pending nickel‐supported upgraded slag oxide (Ni‐UGSO) catalysts, in powder form, have demonstrated excellent performance and achieved equilibrium in dry reforming, steam reforming and mixed methane reforming in a gram‐scale laboratory packed bed reactor under barometric pressure. In this extended study, Ni‐UGSO pellets were prepared using the wet impregnation method. The pelletized form of said catalyst was studied under elevated pressure to imitate the industrial operating conditions in a kilogram‐scale laboratory packed bed reactor. The characterization of the fresh and used catalytic formulation produced data allowing the investigation of the physicochemical properties of catalysts and the effects of metal dispersion, reaction pressure and crystallite size, as well as the role of side reactions on the nature of the coke. The metal support nature favored the interaction between the Ni metal and spinels (UGSO), and the presence of the clay binder (kaolinite, quartz) improved the pellet morphology, provided higher Ni dispersion, maintained the crystallite size, reduced the coke formation and achieved similar or higher performance with respect to Ni‐UGSO powder despite having 85% less surface area. The Ni‐UGSO pellet showed negligible coke deposits from 1 to 6.5 atm and operated successfully for 24 h at 5.5 atm, 800°C and gas hourly space velocity 810 L/(h kg cat). This study provides new insight into the design of a more efficient and robust catalyst for methane dry reforming at elevated pressures, which is critical for potential future transfer at the industrial level.
Mango peel extracts and mangiferin chromatographic Fourier‐transform infrared correlation with antioxidant, antidiabetic, and advanced glycation end product inhibitory potentials using in silico modeling and in vitro assays
Authors: Amin Adnan , Ullah Niamat , Khan Mohsin Abbas , Elsadek Mohamed Farouk , Elshikh Mohamed S. , Hasnain Syed Zia Ul , Baloch Rabia , Chaman Sadia , Makhkamov Trobjon , Yuldashev Akramjon , Yunusov Salohiddinjon , Biturku Jonida 
Published: July 2024

AbstractMangifera indica peels are a rich source of diverse flavonoids and xanthonoids; however, generally these are discarded. Computational studies revealed that mangiferin significantly interacts with amino acid residues of transcriptional regulators 1IK3, 3TOP, and 4f5S. The methanolic extract of Langra variety of mangoes contained the least phenol concentrations (22.6 ± 0.32 mg/gGAE [gallic acid equivalent]) compared to the chloroform (214.8 ± 0.12 mg/gGAE) and ethyl acetate fractions (195.6 ± 0.14 mg/gGAE). Similarly, the methanolic extract of Sindhri variety contained lower phenol concentrations (42.3 ± 0.13 mg/gRUE [relative utilization efficiency]) compared with the chloroform (85.6 ± 0.15 mg/gGAE) and ethyl acetate (76.1 ± 0.32 mg/gGAE) fractions. Langra extract exhibited significant α‐glucosidase inhibition (IC50 0.06 mg/mL), whereas the ethyl acetate fraction was highly active (IC50 0.12 mg/mL) in Sindhri variety. Mangiferin exhibited significant inhibition (IC50 0.026 mg/mL). A moderate inhibition of 15‐LOX was observed in all samples, whereas mangiferin was least active. In advanced glycation end product inhibition assay, the chloroform fraction of Langra variety exhibited significant inhibition in nonoxidative (IC50 64.4 μg/mL) and oxidative modes (IC50 54.7 μg/mL). It was concluded that both Langra and Sindhri peel extracts and fractions possess significant antidiabetic activities. The results suggest the potential use of peel waste in the management and complications of diabetes.
Validation of a bioanalytical HPLC–UV method to quantify Α‐Bisabolol in rat plasma applied to pharmacokinetic pilot study with the drug nanoemulsion
Authors: da Hora Borges Matheus Antônio , Santos de Araújo Jackeline Marley , Pereira Laiz Campos , Santos Luisa Oliveira , Santos Valdeene Vieira , Santos Santana Lorena , de Souza Siqueira Quintans Jullyana , Rodrigues Marcelino Henrique , Rambo Douglas Fernando , Azeredo Francine Johansson 
Published: July 2024

Abstractα‐Bisabolol (α‐BIS) is a sesquiterpene alcohol present in chamomile essential oil [Chamomilla recutita (L.) Rauschert]. Despite its numerous pharmacological effects, its pharmacokinetics remain understudied. An analytical method capable of quantifying α‐BIS in plasma is crucial to enable pharmacokinetic analysis. Presently, only one study has quantified it using mass spectrometry. Administering α‐BIS requires a nanoemulsion for intravenous injection. This study aimed to develop and validate a bioanalytical method using high‐performance liquid chromatography with an ultraviolet detector to quantify α‐BIS in rat plasma. The method employed acetonitrile and ultrapure water (80:20, v/v) as the mobile phase, with a flow rate of 1 ml/min and concentrations ranging from 465 to 29.625 μg/ml. All US Food and Drug Administration‐designated assays were successful, indicating the method's precision, accuracy, sensitivity and linearity in determining α‐BIS in rat plasma. The developed nanoemulsion, assessed through dynamic light scattering analysis, the ensemble collection of particles and polydispersity index evaluation, proved safe and effective for intravenous administration. The pharmacokinetic parameters such as volume of distribution, clearance and half‐life indicated that α‐BIS tends to persist in the body. This study provides a foundation for further research to explore α‐BIS's potential pharmaceutical applications in the future.
Vision‐related quality of life after unilateral occipital stroke
Authors: Dogra Neil , Redmond Bryan V. , Lilley Selena , Johnson Brent A. , Lam Byron L. , Tamhankar Madhura , Feldon Steven E. , Fahrenthold Berkeley , Yang Jingyi , Huxlin Krystel R. , Cavanaugh Matthew R. 
Published: July 2024

Background/objectivesStroke damage to the primary visual cortex induces large, homonymous visual field defects that impair daily living. Here, we asked if vision‐related quality of life (VR‐QoL) is impacted by time since stroke.Subjects/methodsWe conducted a retrospective meta‐analysis of 95 occipital stroke patients (female/male = 26/69, 27–78 years old, 0.5–373.5 months poststroke) in whom VR‐QoL was estimated using the National Eye Institute Visual Functioning Questionnaire (NEI‐VFQ) and its 10‐item neuro‐ophthalmic supplement (Neuro10). Visual deficit severity was represented by the perimetric mean deviation (PMD) calculated from 24‐2 Humphrey visual fields. Data were compared with published cohorts of visually intact controls. The relationship between VR‐QoL and time poststroke was assessed across participants, adjusting for deficit severity and age with a multiple linear regression analysis.ResultsOccipital stroke patients had significantly lower NEI‐VFQ and Neuro10 composite scores than controls. All subscale scores describing specific aspects of visual ability and functioning were impaired except for ocular pain and general health, which did not differ significantly from controls. Surprisingly, visual deficit severity was not correlated with either composite score, both of which increased with time poststroke, even when adjusting for PMD and age.ConclusionsVR‐QoL appears to improve with time postoccipital stroke, irrespective of visual deficit size or patient age at insult. This may reflect the natural development of compensatory strategies and lifestyle adjustments. Thus, future studies examining the impact of rehabilitation on daily living in this patient population should consider the possibility that their VR‐QoL may change gradually over time, even without therapeutic intervention.
Assessing the impact of Industry 4.0 technologies on the social sustainability of agrifood companies
Authors: Cricelli Livio , Mauriello Roberto , Strazzullo Serena , Camilleri Mark Anthony 
Published: July 2024

AbstractIndustry 4.0 technologies present new opportunities for the sustainable development of companies in the agrifood industry. The extant literature on this topic suggests that innovative technologies can support agrifood companies in addressing environmental, economic and social sustainability issues. While the environmental and economic benefits of technological innovations in the agrifood industry have been widely investigated, few studies sought to explore the impact of the adoption of Industry 4.0 technologies on long‐standing social issues. This research addresses this knowledge gap, the data were gathered from 116 Italian agrifood companies that utilized Industry 4.0 technologies. The findings from structural equations modelling partial least squares (SEM‐PLS) show that adopting Industry 4.0 technologies helps agrifood companies to improve human resources management, supply chain management and stakeholder relationships. Finally, this contribution puts forward implications for practitioners, as it raises awareness on the benefits of using technological innovations to promote social sustainability outcomes.
Leptin‐mediated suppression of lipoprotein lipase cleavage enhances lipid uptake and facilitates lymph node metastasis in gastric cancer
Authors: Xiao Jian , Cao Shuqing , Wang Jiawei , Li Pengyu , Cheng Quan , Zhou Xinyi , Dong Jiacheng , Li Yuan , Zhao Xinyu , Xu Zekuan , Yang Li 
Published: July 2024

AbstractBackgroundLymph node metastasis (LNM) is the primary mode of metastasis in gastric cancer (GC). However, the precise mechanisms underlying this process remain elusive. Tumor cells necessitate lipid metabolic reprogramming to facilitate metastasis, yet the role of lipoprotein lipase (LPL), a pivotal enzyme involved in exogenous lipid uptake, remains uncertain in tumor metastasis. Therefore, the aim of this study was to investigate the presence of lipid metabolic reprogramming during LNM of GC as well as the role of LPL in this process.MethodsIntracellular lipid levels were quantified using oil red O staining, BODIPY 493/503 staining, and flow cytometry. Lipidomics analysis was employed to identify alterations in intracellular lipid composition following LPL knockdown. Protein expression levels were assessed through immunohistochemistry, Western blotting, and enzyme‐linked immunosorbent assays. The mouse popliteal LNM model was utilized to investigate differences in LNM. Immunoprecipitation and mass spectrometry were employed to examine protein associations. In vitro phosphorylation assays and Phos‐tag sodium dodecyl‐sulfate polyacrylamide gel electrophoresis assays were conducted to detect angiopoietin‐like protein 4 (ANGPTL4) phosphorylation.ResultsWe identified that an elevated intracellular lipid level represents a crucial characteristic of node‐positive (N+) GC and further demonstrated that a high‐fat diet can expedite LNM. LPL was found to be significantly overexpressed in N+ GC tissues and shown to facilitate LNM by mediating dietary lipid uptake within GC cells. Leptin, an obesity‐related hormone, intercepted the effect exerted by ANGPTL4/Furin on LPL cleavage. Circulating leptin binding to the leptin receptor could induce the activation of inositol‐requiring enzyme‐1 (IRE1) kinase, leading to the phosphorylation of ANGPTL4 at the serine 30 residue and subsequently reducing its binding affinity with LPL. Moreover, our research revealed that LPL disrupted lipid homeostasis by elevating intracellular levels of arachidonic acid, which then triggered the cyclooxygenase‐2/prostaglandin E2 (PGE2) pathway, thereby promoting tumor lymphangiogenesis.ConclusionsLeptin‐induced phosphorylation of ANGPTL4 facilitates LPL‐mediated lipid uptake and consequently stimulates the production of PGE2, ultimately facilitating LNM in GC.
Norms of equality reduce prejudice towards migrants, but only among conservatives
Authors: Long Feiteng , Pliskin Ruthie , Scheepers Daan 
Published: July 2024

AbstractPeople are sensitive to norms, but under what conditions promoting anti‐prejudice norms reduce prejudice remains unclear. Three studies among Dutch participants (total N = 700) examined the effects of (in)equality norms on prejudice towards migrants. To gain greater clarity, we also examined how potential boundary conditions—namely economic and social ideologies—moderate this relationship. A norm of equality was measured (Study 1) or manipulated (Studies 2a and 2b). In Study 1, a perceived norm of equality predicted lower prejudice towards migrants, operationalised as cold feelings, social distance, and perceived outgroup threat, through the increased personal endorsement of equality, particularly among (economic) rightists. In two experiments (Studies 2a and 2b), as well as in a joint analysis of both studies, we found that inducing an equality norm (vs. not) mitigated prejudice towards migrants, but only among (social) rightists. These findings highlight the positive role of social norms promoting equality in combating prejudice and the importance of considering boundary conditions for this role, such as ideology. We discuss the implications for theory and practice regarding prejudice (reduction). Please refer to the Supplementary Material section to find this article's .
Determining the frequency of Helicobacter pylori in children with chronic kidney failure and its relationship to gastrointestinal symptoms
Authors: Nezhad Behgol Nemati , Allahverdi Bahar , Motamed Farzaneh , Djalalinia Shirin , Askarian Fahimeh , Fahimi Daryoush , Bazargani Behnaz , Abbasi Arash , Moghtaderi Mastaneh 
Published: July 2024

Key Clinical MessageAs there is no significant mutual relationship between Helicobacter pylori infection and chronic kidney disease in children, its routine study is not justified and is recommended only in symptomatic cases.AbstractChildren suffering from chronic kidney disease (CKD) often complain of indigestion but, if it is accompanied by abdominal pain, it is necessary to investigate and rule out Helicobacter pylori infection to confirm functional dyspepsia. Epidemiological studies in adults have conflicting results regarding the association between Helicobacter pylori infection and CKD. In this study, we determined the prevalence of H. pylori in children with kidney failure and its relationship to their gastrointestinal symptoms. In this retrospective study, 54 children with chronic kidney failure admitted to the hemodialysis ward of the Children's Medical Center, Tehran, Iran between 2012 and 2020 were studied. The mean age of our patients was 11.89 ± 3.99 years and their sex distribution was equal. H. pylori infection was reported in only three patients with 5.6%. Based on our findings, epigastric pain in children was the most common gastrointestinal symptom (70.4%). Among all patients, three patients (5.6%) died, all of them were male (P = 0.075). The most prevalent underlying cause of kidney failure in our patients was neurogenic bladder. We did not find any significant relationship between the increased risk of chronic kidney failure and co‐infection with H. pylori. Investigating the cause of epigastric pain and looking for H. pylori is very important in CKD children under hemodialysis because if they receive a transplant the possibility of gastrointestinal complications will be increased with the use of steroid and immunosuppressive drugs.
Large‐scale synthesis of nano‐ZIF‐90 from zinc chloride application orientation heat storage materials
Authors: Don Ta Ngoc , Van Duong Le , Phuong Nguyen Thi Hong , Huyen Nguyen Thi Thu , Huy Ta Ngoc Thien , Mo Danh , Ha Bui Thi Thanh , Tran Vy Anh 
Published: July 2024

AbstractThe paper presents the results of the first research on the synthesis of nano‐ZIF‐90 from zinc chloride. More specifically, the paper also introduces the results of large‐scale pure nano‐ZIF‐90 synthesis with a high specific surface, uniform cubic crystals, and good thermal strength. ZIF‐90 is synthesized from zinc chloride‐containing medium capillaries, which have both a weak acid center and a strong base center. The post‐synthetic ZIF‐90 was also evaluated for heat storage based on its ability to adsorb water, methanol, and ethanol. XRD, FTIR, SEM, TEM, N2 adsorption and desorption methods, TG mass thermal analysis, and NH3‐TPD/CO2‐TPD were used to study the ZIF‐90 crystallization process with modifications of precursors, solvents, additives, and reaction conditions. From this, a large‐scale synthesis of nano‐ZIF‐90 from high‐efficiency zinc chloride has been derived. DSC measurements are used to evaluate the enthalpy adsorption of water, methanol, and ethanol on ZIF‐90.
Effect of anti‐Agglomerants on carbon dioxide hydrate formation in oil–water systems
Authors: Huang Shaochang , Wang Xiao , Ma Guiyang , Zang Chunyang 
Published: July 2024

AbstractThe experiments in high‐pressure pipelines simulate the formation and fluid of hydrate under deep‐sea conditions, which has practical significance for the deep‐sea landfill of carbon dioxide (CO2) and the safe running of oil and gas pipelines. In this paper, pure water, white oil, CO2, and arquad 2C‐75 were used to study the formation and flow characteristics of CO2 hydrate in the oil–water system with the help of a loop device, and the growth morphology of hydrate was observed through the view‐window on the loop. The experimental results show that in the low water cut system without anti‐agglomerates, hydrate mainly forms on the surface of water droplets and the surface of the free water layer at the bottom of the loop. In the high water cut system, hydrate forms on the pipe wall in the form of hydrate film. Increasing water cuts can shorten the induction period of hydrate formation. Anti‐agglomerates in the oil–water system can inhibit the growth of hydrate film on the pipe wall effectively. Anti‐agglomerates can shorten the induction time of hydrate formation.
Simultaneous state‐estimator tuning and parameter estimation for systems with nonstationary disturbances, multi‐rate data, and measurement delays
Authors: Liu Qiujun A. , McAuley Kimberley B. 
Published: July 2024

AbstractModel‐based monitoring and control of chemical and biochemical processes rely on state estimators such as extended Kalman filters (EKFs) to ensure accurate online model predictions. Accurate predictions depend on appropriate model parameters and suitable state‐estimator tuning factors. Extensions to our previously developed simultaneous parameter estimation and tuning (SPET) method are proposed so that SPET can be used for systems with nonstationary disturbances, time‐varying parameters, multi‐rate data, and measurement delays. A continuous stirred tank reactor (CSTR) case study with simulated data is used to illustrate and test the proposed method. Superior online model predictions and state‐estimator performance are achieved using SPET compared to a traditional approach for parameter estimation and EKF tuning, with improvements in the average sum‐of‐squared prediction errors ranging from 3% to 52% for the scenarios tested. The SPET approach will also be useful for more‐advanced state estimators that require the same tuning information as EKFs.
Silver Complex Bearing N‐Heterocyclic Carbene Bidentate Chelating Ligand as an Efficient Catalyst in Solvent‐Free KA2 Coupling
Authors: Mateus Miguel , Rycek Lukas 
Published: July 2024

AbstractWe report a synthesis of silver complexes bearing chelating bidentate N‐heterocyclic carbene, with various substitutions at the terminal positions of the imidazole moiety of the NHC units. The long aliphatic substituents proved to be beneficial in terms of the synthetic efficiency of the complexes, compared to previously reported methyl substitution. The complexes demonstrated excellent suitability for the KA2 coupling reaction, providing quaternary carbon‐containing propargylic amines in yields up to 95 %, under solvent‐free conditions. The method showed high tolerance for a wide range of substrates, including naturally occurring ketones, underscoring its practicality. To our knowledge, this represents the first use of a well‐defined silver species in KA2 coupling, marking an advancement in the field.