bluuebunny/crossref_metadata_2025_split huggingface dataset:
Toward a unified framework for understanding the various symptoms and etiology of autism andWilliams syndrome
Authors: Inui Toshio 
Published: February 2013

AbstractTo date, the unifying pathogenesis, or etiology, of autism spectrum disorders (ASDs) and Williams syndrome (WS) remains unknown, partly because of the broad variation of phenotypes and the heterogeneity of syndrome expression. In particular, in order to comprehend the etiological mechanisms of their characteristic behaviors, great importance should be placed on realizing how the neural networks of individuals with autistic disorders andWSare formed and work. As such, in this paper, cortical network abnormalities, based on data from a variety of research fields, are presented: psychopathological, histopathological, and clinicopathological studies, as well as structural (i.e., morphological) and functional magnetic resonance imaging studies, including functional connectivity analysis. Based on the structure of the network, we propose an etiology forASDandWS. Finally, we explain a variety of symptoms of these two disorders, including social and nonsocial dysfunction, based on our proposed neural network.
Draft Genome Sequence of a Phosphate-Accumulating
Bacillus
sp., WBUNB004
Authors: DebRoy Shreya , Mukherjee Pallavi , Roy Sujata , Thakur Ashoke Ranjan , RayChaudhuri Shaon 
Published: February 2013

ABSTRACT

The draft genome sequence of a nitrate- and phosphate-removing, Gram-positive
Bacillus
sp. with optimum growth at 37°C and pH 7 in nitrate broth (HiMedia M439) isolated from rhizosphere of a water lily, with a genome size of 5,465,157 bp and a G+C content of 35.0%, is reported here.
Draft Genome Sequence of a Nitrate- and Phosphate-Removing
Bacillus
sp., WBUNB009
Authors: DebRoy Shreya , Mukherjee Pallavi , Roy Sujata , Thakur Ashoke Ranjan , RayChaudhuri Shaon 
Published: February 2013

ABSTRACT

The draft genome sequence (5,868,741 bp) of a nitrate- and phosphate-removing
Bacillus
sp., WBUNB009, isolated from a raw sewage canal in nitrate broth (Himedia M439) with a G+C content of 34.9% is reported. It removes 60.23% nitrate and 96% phosphate within 16 h at 37°C.
Spatial Distributions and Seasonal Variations of Tropospheric Water Vapor Content over the Tibetan Plateau
Authors: Zhang Yuwei , Wang Donghai , Zhai Panmao , Gu Guojun , He Jinhai 
Published: February 2013

Abstract
Spatial distributions and seasonal variations of tropospheric water vapor over the Tibetan Plateau and the surrounding areas are explored by means of water vapor products from the high-resolution Atmospheric Infrared Sounder (AIRS) on board the Aqua satellite and the NASA Water Vapor Project (NVAP). Because NVAP has a serious temporal inhomogeneity issue found in previous studies, the AIRS retrieval product is primarily applied here, though similar seasonal variations can be derived in both datasets. Intense horizontal gradients appear along the edges of the plateau in the lower-tropospheric (500–700 hPa) water vapor and columnar precipitable water, in particular over the regions along the southeastern boundary. Rich horizontal structures are also seen within the plateau, but with a weaker gradient. In the mid- to upper troposphere (300–500 hPa), horizontal gradients are relatively weak. It is shown that there is always a deep layer of high water vapor content over the plateau with a peak around 500 hPa, which can extend from the surface to roughly 300 hPa and even to 100 hPa at some locations. This layer of high water vapor content has consistent influence on precipitating processes in the downstream regions such as the valleys of the Yellow and Yangtze Rivers. Estimated vertically integrated water vapor flux and moisture divergence in the two layers (500–700 and 300–500 hPa) further confirm the effect of the Tibetan Plateau on the downstream regions. In particular, the mid- to upper-layer water vapor (300–500 hPa) tends to play an essential role during both the warm and cold seasons, confirmed by the spatial distribution of seasonal-mean precipitation.
ETHNOPRED: a novel machine learning method for accurate continental and sub-continental ancestry identification and population stratification correction
Authors: Hajiloo Mohsen , Sapkota Yadav , Mackey John R , Robson Paula , Greiner Russell , Damaraju Sambasivarao 
Published: February 2013

Abstract

Background
Population stratification is a systematic difference in allele frequencies between subpopulations. This can lead to spurious association findings in the case-control genome wide association studies (GWASs) used to identify single nucleotide polymorphisms (SNPs) associated with disease-linked phenotypes. Methods such as self-declared ancestry, ancestry informative markers, genomic control, structured association, and principal component analysis are used to assess and correct population stratification but each has limitations. We provide an alternative technique to address population stratification.

Results
We propose a novel machine learning method, ETHNOPRED, which uses the genotype and ethnicity data from the HapMap project to learn ensembles of disjoint decision trees, capable of accurately predicting an individual’s continental and sub-continental ancestry. To predict an individual’s continental ancestry, ETHNOPRED produced an ensemble of 3 decision trees involving a total of 10 SNPs, with 10-fold cross validation accuracy of 100% using HapMap II dataset. We extended this model to involve 29 disjoint decision trees over 149 SNPs, and showed that this ensemble has an accuracy of ≥ 99.9%, even if some of those 149 SNP values were missing. On an independent dataset, predominantly of Caucasian origin, our continental classifier showed 96.8% accuracy and improved genomic control’s λ from 1.22 to 1.11. We next used the HapMap III dataset to learn classifiers to distinguish European subpopulations (North-Western vs. Southern), East Asian subpopulations (Chinese vs. Japanese), African subpopulations (Eastern vs. Western), North American subpopulations (European vs. Chinese vs. African vs. Mexican vs. Indian), and Kenyan subpopulations (Luhya vs. Maasai). In these cases, ETHNOPRED produced ensembles of 3, 39, 21, 11, and 25 disjoint decision trees, respectively involving 31, 502, 526, 242 and 271 SNPs, with 10-fold cross validation accuracy of 86.5% ± 2.4%, 95.6% ± 3.9%, 95.6% ± 2.1%, 98.3% ± 2.0%, and 95.9% ± 1.5%. However, ETHNOPRED was unable to produce a classifier that can accurately distinguish Chinese in Beijing vs. Chinese in Denver.

Conclusions
ETHNOPRED is a novel technique for producing classifiers that can identify an individual’s continental and sub-continental heritage, based on a small number of SNPs. We show that its learned classifiers are simple, cost-efficient, accurate, transparent, flexible, fast, applicable to large scale GWASs, and robust to missing values.
Periodic knee injections of collagen tripeptide delay cartilage degeneration in rabbit experimental osteoarthritis
Authors: Naraoka Takuya , Ishibashi Yasuyuki , Tsuda Eiichi , Yamamoto Yuji , Kusumi Tomomi , Toh Satoshi 
Published: February 2013

Abstract
Introduction
Collagen peptides have been reported to possess various biological activities for various cell types. The purposes of this study were, first, to examine the therapeutic effects of collagen tripeptide (Ctp) in rabbit osteoarthritis and, second, to explore a synergetic effect with hyaluronan (HA).

Methods
Osteoarthritis was induced by anterior cruciate ligament transection of the right knee in 72 Japanese white rabbits and they were divided into four groups (control, Ctp, HA and Ctp/HA). Each material was injected weekly into the knee, and knee joint samples were collected 5, 10 and 15 weeks after surgery. Macroscopic and histomorphological analyses of cartilage were conducted. Expression of type II collagen and matrix metalloproteinase-13 was also analyzed immunohistochemically. A Tukey's honestly significant difference test was used to evaluate the statistical significance of difference in the macroscopic, histological and immnohistochemical results.

Results
All treatment groups exhibited slightly higher resistance to the progression of osteoarthritis than the control group macroscopically 15 weeks after surgery. Histologically, intra-articular injection of Ctp significantly reduced cartilage degradation 10 weeks after surgery, and Ctp/HA significantly reduced it 5 weeks after surgery in comparison with the control. Immunohistochemically, both Ctp-treated and Ctp/HA-treated groups had significantly increased type II collagen-positive chondrocytes at the fifth week after the surgery, although the numbers of matrix metalloproteinase-13-positive chondrocytes were not affected.

Conclusion
Periodical injections of Ctp and Ctp/HA delayed progression of cartilage degeneration of early osteoarthritis induced by anterior cruciate ligament transection in rabbits. This effect appears to be exerted by promotion of type II collagen synthesis predominantly.
Le Chemin de Povreté Et de Richesse and the Late Medieval Social Imaginary
Authors: Epurescu-Pascovici Ionuț 
Published: February 2013

Authored by a modest legal professional, Le chemin de povreté et de richesse offers a remarkable entry point into the late medieval social imaginary, bringing into focus the views of the urban laity. Responding to socioeconomic instability, the author articulates a model of conduct that relies on pragmatic rationality (personified by Raison [Reason]), work, and self-discipline for the attainment of a moderate but secure social standing. While religious ethics remain important, socioeconomic factors are treated in their own right. Reflecting a complex social imaginary, the text offers a moment of genuine dialogism when maistre Barat (Deceit), the personification of the arrivistes who rely on fraud and sycophancy, defends his own path to success. The chastel de Labour, populated not by knights but by “more than a hundred thousand laborers,” subverts the hierarchy of the traditional imaginary of the three orders. This article relates the changes in the social imaginary to the beginnings of European modernity.
Le chemin de povreté et de richesse ouvre une nouvelle perspective sur l’imaginaire social du bas Moyen Age, plus proche du monde de la bourgeoisie (son auteur est un modeste homme de loi). Face à l’instabilité socio-économique, l’auteur conçoit un programme d’action qui vise un statut social moyen mais durable, s’appuyant sur les valeurs de la rationalité pratique, du labeur et de l’autodiscipline. Bien que les valeurs religieuses restent importantes, la réalité socio-économique reçoit un statut autonome. La confrontation entre les personnages allégoriques Raison et maître Barat relève d’un dialogisme authentique et d’un imaginaire social complexe. Avec la vision d’un chastel de Labour peuplé non par des chevaliers mais par « plus de cent mille ouvriers », l’auteur se distancie de l’imaginaire traditionnel et hiérarchique des trois ordres. Les changements observés dans l’imaginaire social du bas Moyen Age sont examinés à la fin de cet article par rapport à l’émergence de la modernité européenne.
The depth of the honeybee's backup sun-compass systems
Authors: Dovey Katelyn M. , Kemfort Jordan R. , Towne William F. 
Published: February 2013

SummaryHoneybees have at least three compass mechanisms: a magnetic compass; a celestial or sun compass, based on the daily rotation of the sun and sun-linked skylight patterns; and a backup celestial compass based on a memory of the sun's movements over time in relation to the landscape. The interactions of these compass systems have yet to be fully elucidated, but the celestial compass is primary in most contexts, the magnetic compass is a backup in certain contexts, and the bees' memory of the sun's course in relation to the landscape is a backup system for cloudy days. Here we ask whether bees have any further compass systems, for example a memory of the sun's movements over time in relation to the magnetic field. To test this, we challenged bees to locate the sun when their known celestial compass systems were unavailable, that is, under overcast skies in unfamiliar landscapes. We measured the bees' knowledge of the sun's location by observing their waggle dances, by which foragers indicate the directions toward food sources in relation to the sun's compass bearing. We found that bees have no celestial compass systems beyond those already known: Under overcast skies in unfamiliar landscapes, bees attempt to use their landscape-based backup system to locate the sun, matching the landscapes or skylines at the test sites with those at their natal sites as best they can, even if the matches are poor and yield weak or inconsistent orientation.
Immediate Loading Implant Dentistry Strategies Have Their Origins in Periodontal Prosthesis
Authors: Ganeles Jeffrey , Rose Louis F. , Norkin Frederic J. , Zfaz Samuel 
Published: February 2013

Introduction: The principles of periodontal prosthesis developed in the 1950s to 1970s by Drs. Amsterdam, Abrams, and Weisgold and explained in Periodontal Therapy, edited by Drs. Goldman and Cohen, provide relevant diagnostic and therapeutic criteria and guidelines that apply to teeth as well as implants. For these situations, occlusal, restorative, surgical, esthetic, biomaterial, pharmacologic, and psychologic skills must be carefully combined for optimal results. These points are illustrated through a case presentation of a challenging patient.Case Presentation: A 62‐year‐old woman presented to her general dentist with a chief complaint of drifting of her recent maxillary anterior restorations. On further questioning, she also complained about pain of these teeth, bilateral temporomandibular muscle pain, and tooth mobility. A treatment plan was developed in conjunction with the patient's restorative dentist to restore the patient to first‐molar occlusion using implants in the maxillary arch and a combination of teeth and implants in the mandibular arch.Conclusion: Combining the guidelines of periodontal prosthesis with state‐of‐the‐art implant dentistry can lead to predictable, beneficial, and efficient treatment, even for the most difficult patients and circumstances.
Insecticide and Food Consumption of Spanish Slug (Arion Lusitanicus Mabille 1868) / Insektycydy A Konsumpcja Pokarmu Przez Ślinika Luzytańskiego (Arion Lusitanicus Mabille 1868)
Authors: Piechowicz Bartosz , Stawarczyk Kinga , Stawarczyk Michał 
Published: February 2013

Abstract
In the years 2007 and 2011, research was carried out on the impact of: pyrethroid group agents (beta-cyfluthrin, lambda-cyhalothrin, deltamethrin, esfenvalerate, alpha-cypermethrin, bifenthrin) benzoylphenyl ureas (teflubenzuron), derivatives of pyridine (pyriproxyfen), organophosphorus (diazinon) and neonicotinoid insecticides (acetamiprid) on the food consumption by Spanish slug (Arion lusitanicus Mab). The quantity of food consumed by animals treated by plant protection agents, the quantity of food treated by insecticides consumed and food preferences of A. lusitanicus individuals were analysed. The slugs were made available a selection between food with an addition of insecticide and without it. The results obtained indicate that the preparations which contained lambda-cyhalothrin and deltamethrin with which the animals were treated increase the quantity of food consumed by the Spanish slug. It was also shown that the food treated with lambdacyhalothrin and alpha cypermethrin is consumed in a larger amount than the food not treated by this preparation. Deltamethrin and lambda-cyhalothrin and pyriproxyfen probably constitute food attractants for A. lusitanicus individuals and also alpha-cypermethrin, bifenthrin, beta-cyfluthrin and esfenvalerate are additive, which reduces the attractiveness of food for slug.
Application of HEC-RAS model for estimating changes in watercourse geometry during floods
Authors: Markowska Joanna , Markowski Jacek , Drabiński Andrzej 
Published: February 2013

Abstract
Groundwater table levels in a river valley depend, among other factors, on meteorological and hydrogeological conditions, land use and water levels in watercourses. The primary role of a watercourse is to collect surface and groundwater, and it becomes an infiltrating watercourse at high water levels. Changes in groundwater levels and the range of these changes depend chiefly on the shape, height and duration of the flood wave in the river channel.
The assessment of flood wave impact on groundwater was based on long-term measurements of groundwater levels in the Odra valley and observations of water levels in the river channel. Simulations were performed with the use of in-house software FIZ (Filtracja i Zanieczyszczenia; Filtration and Contamination), designed for modelling unsteady water flows within a fully saturated zone. A two-dimensional model with two spatial variables was employed. The process of groundwater flow through a porous medium, non-homogeneous in terms of water permeability, was described with Boussinesq equation. The equation was solved with the use of finite element method. The model was applied to assess groundwater level fluctuations in the Odra valley in the context of actual flood waves on the river.
Variations in groundwater table in the valley were analysed in relation to selected actual flood water levels in the Odra in 2001-2003 and 2010. The period from 2001 to 2003 was used to verify the model. A satisfactory agreement between the calculated and the measured values was obtained. Based on simulation calculations, it was proved that flood waves observed in 2010 caused a rise in groundwater table levels in a belt of approximately 1000 metres from the watercourses. It was calculated that at the end of hydrological year 2009/2010, the highest growths, of up to 0.80 m, were observed on piezometers located close to the Odra river channel. The passage of several flood waves on the Odra caused an increase of subsurface retention by 3.0% compared to the initial state.
Proposal for calculating the bearing capacity of screw displacement piles in non-cohesive soils based on CPT results
Authors: Krasiński Adam 
Published: February 2013

Abstract
Screw displacement pile technology is relatively new and is still being developed. A specific characteristic of those piles is their very considerable influence on soil properties during the installation, which renders classical bearing capacity calculation methods insufficient. Some methods for calculating the bearing capacity of screw displacement piles have already been presented in literature, for example, by Bustmante and Gianesselli [2], [3], Van Impe [17], [18], Maertens and Huybrechts [15], Ne Smith [16] as well as Basu and Prezzi [1]. This paper proposes a new method of calculating the bearing capacity of screw displacement piles in non-cohesive soil which is based on CPT results. It has been devised as a result of research project No. N N506 432936 [11], carried out in 2009-2011. At 6 experimental sites screw displacement pile static loading tests were carried out together with CPTU tests of the subsoil. The results allowed us to establish soil resistances along the shaft ts as well as under the pile base qb and their correlations to the CPT soil cone resistances qc. Two approaches, both adapted to the general guidelines of Eurocode 7 (EC7) [20], were proposed: a classical approach and the second approach with load transfer functions application.
Exploratory Assessment of the Limiting Extended Kalman Filter Properties
Authors: Antoniou Constantinos , Kondyli Alexandra , Lykogianni Georgia-Maria , Gyftodimos Elias 
Published: February 2013

Abstract
Most of the methodologies for the solution of state-space models are based on the Kalman Filter algorithm (Kalman, 1960), developed for the solution of linear, dynamic state-space models. The most straightforward extension to nonlinear systems is the Extended Kalman Filter (EKF). The Limiting EKF (LimEKF) is a new algorithm that obviates the need to compute the Kalman gain matrix on-line, as it can be calculated off-line from pre-computed gain matrices. In this research, several different strategies for the construction of the gain matrices are presented: e.g. average of previously computed matrices per interval per demand level and average of previously computed matrices per interval independent of demand level.
Two case studies are presented to investigate the performance of the LimEKF under the different assumptions. In the first case study, a detailed experimental design was developed and a large number of simulation runs was performed in a synthetic network. The results suggest that indeed the LimEKF algorithm is robust and - while not requiring the explicit computation of the Kalman gain matrix, and thus having vastly superior computational properties - its accuracy is close to that of the “exact” EKF. In the second case study, a smaller number of scenarios is evaluated using a real-world, large-scale network in Stockholm, Sweden, with similarly encouraging results. Taking the average of various pre-computed Kalman Gain matrices possibly reduces the noise that creeps into the computation of the individual Kalman gain matrices, and this may be one of the key reasons for the good performance of the LimEKF (i.e. increased robustness).
Efficiency Analysis of Solar Facilities for Building Heating and Household Water Heating Under Conditions in the Czech Republic / Analýza Efektivity Solárnych Zariadení Pre Ohrev Úžitkovej Vody A Vykurovanie Budov V Podmienkach Českej Republiky
Authors: Pivko Michal , Jursová Simona , Turjak Juraj 
Published: February 2013

Abstract
The paper studies the efficiency of solar facilities applied for the heating of buildings and household water heating in the Czech Republic. The Czech Republic is situated in the temperate zone characterized by changeable weather. It is respected in the assessment of a solar facility installation. The efficiency of solar facilities is evaluated according to energy and economic balances. It is analyzed for solar facilities heating both household water and buildings. The main problems relating to the implementation of solar facilities and their operation in the temperate zone with hot summer and freezing winter are discussed.
Remote Sensing Methods in the Identification of Oil Contaminations / Možnosti Využití Vybraných Metod Dpz Pro Identifikaci Ropných Kontaminací (Starých Ekologických Zátěží)
Authors: Smejkalová Eva , Bujok Petr 
Published: February 2013

Abstract
The article deals with the possibilities of using remote sensing methods for analysis, observation and identification of old ecological hazards caused by petroleum contaminations from insufficiently plugged and abandoned oil wells in the area of Hodonín. It is focused on the description and determination of areas of interests, remote sensing approaches to the problems of petroleum substance detection and establishing the methodology of an acquired data analysis. Moreover, proper methods, algorithms and satellite digital data parameters for this aim are discussed. The article also describes in-situ measurements, technical instruments and further research advancements. Finally, the proposals of the results evaluation, interpretation and complex comparisons with the results of past and future researches in the area of Nesyt - Hodonín are specified.