bluuebunny/crossref_metadata_2025_split huggingface dataset:
Estimated incidence of disruptions to event-free survival from non-metastatic cancers in New South Wales, Australia - a population-wide epidemiological study of linked cancer registry and treatment data
Authors: Morrell Stephen , Roder David , Currow David , Engel Alexander , Hovey Elizabeth , Lewis Craig R. , Liauw Winston , Martin Jarad M. , Patel Manish , Thompson Stephen R. , O’Brien Tracey 
Published: August 2024

IntroductionPopulation cancer registries record primary cancer incidence, mortality and survival for whole populations, but not more timely outcomes such as cancer recurrence, secondary cancers or other complications that disrupt event-free survival. Nonetheless, indirect evidence may be inferred from treatment data to provide indicators of recurrence and like events, which can facilitate earlier assessment of care outcomes. The present study aims to infer such evidence by applying algorithms to linked cancer registry and treatment data obtained from hospitals and universal health insurance claims applicable to the New South Wales (NSW) population of Australia.Materials and methodsPrimary invasive cancers from the NSW Cancer Registry (NSWCR), diagnosed in 2001–2018 with localized or regionalized summary stage, were linked to treatment data for five common Australian cancers: breast, colon/rectum, lung, prostate, and skin (melanomas). Clinicians specializing in each cancer type provided guidance on expected treatment pathways and departures to indicate remission and subsequent recurrence or other disruptive events. A sample survey of patients and clinicians served to test initial population-wide results. Following consequent refinement of the algorithms, estimates of recurrence and like events were generated. Their plausibility was assessed by their correspondence with expected outcomes by tumor type and summary stage at diagnosis and by their associations with cancer survival.ResultsKaplan-Meier product limit estimates indicated that 5–year cumulative probabilities of recurrence and other disruptive events were lower, and median times to these events longer, for those staged as localized rather than regionalized. For localized and regionalized cancers respectively, these were: breast - 7% (866 days) and 34% (570 days); colon/rectum - 15% (732 days) and 25% (641 days); lung - 46% (552 days) and 66% (404 days); melanoma - 11% (893 days) and 38% (611 days); and prostate - 14% (742 days) and 39% (478 days). Cases with markers for these events had poorer longer-term survival.ConclusionsThese population-wide estimates of recurrence and like events are approximations only. Absent more direct measures, they nonetheless may inform service planning by indicating population or treatment sub-groups at increased risk of recurrence and like events sooner than waiting for deaths to occur.
Short-term HIIT impacts HDL function differently in lean, obese, and diabetic subjects
Authors: Zhu Lin , An Julia , Luu Thao , Reyna Sara M. , Tantiwong Puntip , Sriwijitkamol Apiradee , Musi Nicolas , Stafford John M. 
Published: August 2024

IntroductionHigh density lipoproteins (HDL) exert cardiovascular protection in part through their antioxidant capacity and cholesterol efflux function. Effects of exercise training on HDL function are yet to be well established, while impact on triacylglycerol (TG)-lowering has been often reported. We previously showed that a short-term high-intensity interval training (HIIT) program improves insulin sensitivity but does not inhibit inflammatory pathways in immune cells in insulin-resistant subjects. The purpose of this study is to evaluate HDL function along with changes of lipoproteins after the short-term HIIT program in lean, obese nondiabetic, and obese type 2 diabetic (T2DM) subjects.MethodsAll individuals underwent a supervised 15-day program of alternative HIIT for 40 minutes per day. VO2peak was determined before and after this training program. A pre-training fasting blood sample was collected, and the post-training fasting blood sample collection was performed 36 hours after the last exercise session.ResultsBlood lipid profile and HDL function were analyzed before and after the HIIT program. Along with improved blood lipid profiles in obese and T2DM subjects, the HIIT program affected circulating apolipoprotein amounts differently. The HIIT program increased HDL-cholesterol levels and improved the cholesterol efflux capacity only in lean subjects. Furthermore, the HIIT program improved the antioxidant capacity of HDL in all subjects. Data from multiple logistic regression analysis showed that changes in HDL antioxidant capacity were inversely associated with changes in atherogenic lipids and changes in HDL-TG content.DiscussionWe show that a short-term HIIT program improves aspects of HDL function depending on metabolic contexts, which correlates with improvements in blood lipid profile. Our results demonstrate that TG content in HDL particles may play a negative role in the anti-atherogenic function of HDL.
The impact of attitude toward COVID-19 vaccine on intention to receive influenza vaccination: a multi-group comparison based on the influence of presumed influence model and spillover effects
Authors: Zhang Yun , Yi Hongfa 
Published: August 2024

IntroductionInfluenza vaccination is one of the most important strategies for preventing influenza. However, the influenza vaccination rate in China remains low. During the COVID-19 pandemic, people held different attitudes toward the COVID-19 vaccine. In the post-pandemic era, do the varying attitudes toward the COVID-19 vaccine affect the intention to receive influenza vaccination?MethodsBased on the influence of presumed influence (IPI) model and spillover effects, this study employed structural equation modeling for multi-group comparison to analyze questionnaires from 613 participants, using instruments such as the Perceived Media Influence on Others Scale (PMIO), the Susceptibility to Influenza Scale (SI), and the Attitude toward Influenza Vaccine Scale (AIV).ResultsThe key findings are as follows: (1) Information exposure to the influenza vaccine significantly influences perceived media influence on others. (2) Perceived media influence on others does not directly impact the intention to receive influenza vaccination but rather affects it through attitude toward the influenza vaccine. (3) Moreover, multi-group analyses revealed differences in the IPI model among audiences with different attitudes toward the COVID-19 vaccine. These differences demonstrated that prior attitudes toward the COVID-19 vaccine can influence attitudes toward similar influenza vaccines, thus demonstrating the existence of spillover effects.ConclusionAttitude toward the COVID-19 vaccine can influence the intention to receive the influenza vaccination. Those with a negative attitude toward the COVID-19 vaccine are significantly influenced by susceptibility to influenza. Perceived media influence affects the intention to receive the influenza vaccination among those with a positive attitude toward the COVID-19 vaccine.
Barriers to care for musculoskeletal sarcoma patients: a public health perspective
Authors: Syros Alina , Baron Max C. , Adalbert Jenna , Remer Hallie B. , Heng Marilyn , Crawford Brooke 
Published: August 2024

IntroductionThis study seeks to investigate the barriers to care that exist for patients presenting with sarcomas of musculoskeletal origin. Understanding the roots of delays in care for patients with musculoskeletal sarcoma is particularly important given the necessity of prompt treatment for oncologic diagnoses. Investigators reviewed relevant studies of publications reporting barriers to care in patients undergoing diagnosis and treatment of musculoskeletal tumors.MethodsA comprehensive literature search was conducted using Scopus, Embase, Web of Science, and PubMed-MEDLINE. Twenty publications were analyzed, including a total of 114,056 patients.ResultsFour barrier subtypes were identified: Socioeconomic Status, Geographic Location, Healthcare Quality, Sociocultural Factors. Socioeconomic status included access to health insurance and income level. Geographic location included distance traveled by patients, access to referral centers, type of hospital system and resource-challenged environments. Healthcare quality included substandard imaging, access to healthcare resources, and healthcare utilization prior to diagnosis. Sociocultural factors included psychological states, nutrition, education and social support.ConclusionAfter identifying the most significant barriers in this study, we can target specific public health issues within our community that may reduce delays in care. The assessment of barriers to care is an important first step for improving the delivery of oncologic patient care to this patient population.
Suicide warning signs of self-identification in patients with mood disorders: a qualitative analysis based on safety planning
Authors: Zhang Honghui , Zhu Jiaxin , Niu Lu , Zeng Meng , Chen Tengwei , Chen Yuedong , Hou Xiaofei , Tao Haojuan , Ma Yarong , Lin Kangguang , Zhou Liang 
Published: August 2024

IntroductionWarning signs serve as proximal indicators of suicide risk, making early recognition imperative for effective prevention strategies. This study aimed to explore self-identified suicide warning signs among Chinese patients with mood disorders based on safety planning framework.MethodsResearchers collaborated with patients to develop a safety plan and compiled warning signs based on it. Word frequency and network analysis were conducted to identify key warning signs. Directed content analysis categorized these signs into cognitive, emotional, behavioral, or physiological themes according to the suicide mode theory. Additionally, we examined potential variations in reported warning signs among participants with different demographic characteristics, including age, gender, and history of suicide attempts.Results“Low mood” and “crying” emerged as prominent warning signs, with “social withdrawal” closely following. Patients commonly reported emotional themes during suicidal crises, often experiencing two to three themes simultaneously, primarily focusing on emotional, behavioral, and physiological themes. Males exhibited a higher proportion of concurrently reporting three sign themes compared to females (P &lt; 0.05), while no difference was observed in warning signs among patients with other demographic traits.DiscussionThis study offers a nuanced understanding of warning signs among mood disorder patients in China. The findings underscore the necessity for comprehensive suicide risk management strategies, emphasizing interventions targeting emotional regulation and social support. These insights provide valuable information for enhancing suicide prevention and intervention efforts.
From trauma to resilience: advancing cultural responsiveness and equity in the Muskowekwan First Nation’s healing journey
Authors: Sasakamoose JoLee , Pete Shauneen , O’Soup Fred , Wolfe Tiffany 
Published: August 2024

IntroductionThe Muskowekwan First Nation (MFN) in Saskatchewan, Canada, epitomizes the enduring strength and cultural preservation of the Saulteaux people. This community faces the lasting effects of colonial trauma, especially the violence, abuse, and adversity experienced by students at the Muskowequan Indian Residential School (MIRS). Decades of abuse by institutional leaders caused generational trauma, contributing to current mental health and well-being challenges. This study highlights the community’s role in sharing experiences and shaping healing processes to develop the MFN Family Healing and Wellness Centre in response to urgent community concerns. It examines the integration of Justice, Diversity, Equity, and Inclusion (J-DEI) principles and cultural responsiveness in fostering community resilience and mental well-being.MethodsAdopting a community-based participatory research framework, this study employs a mixed-methods approach, including community engagement sessions and surveys. Collaborating closely with the MFN leadership, it draws upon the specialized expertise of Author2 and Author1, leaders in Indigenous health and research. The research uses qualitative and quantitative data collection, emphasizing the importance of community input and leadership in shaping the research process and outcomes.ResultsFindings emphasize the community’s commitment to spiritual and cultural practices as vital healing components. Amidst the heightened awareness of the lingering effects of the MIRS within the MFN community, these insights informed the development of the Centre, ensuring it incorporates the community’s desires for culturally relevant healing practices. The grand opening of Phase I of the Centre in February 2023 emerged as a significant step forward, symbolizing a move towards holistic community health that honors resilience, holistic wellness, and cultural continuity.DiscussionThis case study contributes to the literature on integrated, culturally responsive healthcare models that address the needs of Indigenous peoples and communities. The study provides insights to guide the Centre’s future programs and services, ensuring they are culturally tailored and responsive to the community’s needs. By illustrating the potential for traditional wisdom and contemporary health practices to foster well-being, the case study advocates for holistic approaches to healing in Indigenous settings, offering a replicable framework for similar initiatives globally.
The impact of social activities on mental health among older adults in China
Authors: Gao Duanyang , Li Rui , Yang Yuying 
Published: August 2024

BackgroundUnderstand the current situation of social activities among older adults and its impact on mental health, providing policy basis and intervention measures to improve the mental health of the older adult.MethodCollect relevant data from 8,181 older adults aged ≥ 60 years old from the 2020 China Health and Retirement Longitudinal Study (CHARLS), constructing an analysis framework for social activities of older adults in China from three aspects: participation in social activities, number of social activities, frequency of social activities, and describe them, then analyzing the impact of social activities on their mental health using OLS and 2SLS regression models. This study also discusses the impact of eight social activities on the mental health of older adult people through subgroup.ResultAmong 8,181 older adults aged 60 and above, 3,808 participated in social activities (56.24%), average number of social activities is 0.71, and average frequency of social activities is 1.31 times. The average score of mental health level measured by CES-D is 15.24 points. Participate in social activities can reduce the depression level of the older adult (β = −0.352, 95%CI: −0.547~−0.158); the more social activities the older adult participate in, the lower the depression level of the older adult (β = −0.214, 95%CI: −0.313~−0.115); the higher the frequency of participating in social activities, the lower the depression level of the older adult (β = −0.133, 95%CI: −0.182~−0.083). In summary, social activities can improve the mental health level of the older adults in China. As for different types of social activities, visiting and socializing with friends, participating in club organization activities, playing mahjong, chess, cards, or going to community activity rooms and attending school or training courses can improve the mental health of the older adult.DiscussionThe social activities in three dimensions among older adults in China need to be further improved, and participating in social activities can help improve their mental health. The conclusion provides important policy implications for encouraging and supporting older adults to participate in various social activities, increasing the number and frequency of older adult social activities, then help improving the mental health level of older adults.
Scaling community-based aquaculture for enhanced nutrition and women’s empowerment: lessons from Odisha, India
Authors: Dubey Sourabh Kumar , Padiyar Arun , Chadag Vishnumurthy Mohan , Shenoy Neetha , Gaikwad Amar Bharat , Ratha Baishnaba Charan , Belton Ben 
Published: August 2024

IntroductionAquatic foods, particularly fish, are essential for addressing malnutrition, especially in vulnerable populations like children and women. In India, traditional aquaculture practices centered around carp species often overlooked the production of nutrient-rich small fish. To address this, nutrition-sensitive aquaculture approaches advocate for integrating species like mola carplet (Amblypharyngodon mola) rich in micronutrients, into existing systems. In Odisha, India, where poverty and food insecurity are prevalent, the government initiated a program to empower women through aquaculture, focusing on nutrition-sensitive carp-mola polyculture in community ponds through Women Self-Help Groups (WSHGs).MethodsThis study evaluates the effectiveness of this government program in enhancing income, household nutrition, and women’s empowerment. Data from field surveys conducted across all 30 districts of Odisha were analyzed to assess participation, capacity building, adoption of better management practices (BMPs), productivity of carp-mola polyculture, household fish consumption, and profitability.Results and discussionThe study found widespread participation and adoption of BMPs among WSHGs, leading to increased productivity and income. Carp-mola polyculture systems showed higher productivity and consumption rates, contributing to improved nutrition among WSHGs and their communities. Despite challenges such as input costs and limited mola availability, WSHGs reported profitability from fish farming, with carp-mola polyculture systems yielding higher net income. Factors influencing productivity and profitability included water retention period, stocking density, feed application, and training. The program’s impact extended beyond economic benefits, encompassing environmental improvement, women’s empowerment, and enhanced nutrition outcomes.The study highlights the success of the government program in promoting sustainable aquaculture practices and improving nutrition outcomes in Odisha. Continued support, capacity building, and collaboration among stakeholders are essential for scaling up nutrition-sensitive aquaculture interventions and ensuring long-term sustainability. Strengthening dissemination processes, addressing challenges, and further research on small indigenous fish production techniques are crucial for maximizing the program’s impact on food security and rural development.
ANTY-CYTOKINE ACTIVITY OF GENUS ENTEROCOCCUS BACTERIA ISOLATED FROM ANIMALS
Authors: Карташова Ольга Львовна , Пашкова Татьяна Михайловна , Сычёва Мария Викторовна , Кочкина Елена Евгеньевна 
Published: August 2024

Статья посвящена изучению антицитокиновой активности энтерококков различного происхождения. Опыты in vitro проведены на 84 штаммах энтерококков разных видов, выделенных из фекалий здоровых продуктивных животных и от животных с инфекционно-воспалительными заболеваниями. Антицитокиновую активность бактерий рода Enterococcus в отношении фактора некроза опухоли и интерлейкина-10 определяли фотометрически по методике О.В. Бухарина с соавт. (2011). Полученные данные были обработаны статистически. Результаты исследования свидетельствуют о широком распространении антицитокинового признака в популяции фекальных и клинических изолятов энтерококков. Среди энтерококков кишечного происхождения отмечена широкая распространённость антицитокиновой активности в отношении фактора некроза опухоли, в то время как среди клинических изолятов доминировали культуры Enterococcus spp., способные деградировать/связывать интерлейкин-10. Полученные результаты не только расширяют представления об иммуномодулирующей и противовоспалительной функции симбиотических энтерококков кишечного биотопа, но и могут быть использованы для дифференциации бактерий рода Enterococcus на симбиотические и этиологически значимые штаммы.
The article is devoted to the study of the anti-cytokine activity of enterococci of various origin. In vitro experiments were carried out on 84 strains of enterococci of various species isolated from the feces of the healthy productive animals and from the animals with infectious and inflammatory diseases. The anti-cytokine activity of bacteria of the genus Enterococcus with respect to tumor necrosis factor and interleukin-10 was determined photometrically by the method of O.V. Bukharin et al. (2011). The data obtained was statistically processed. The results of the study indicate a wide distribution of the anti-cytokine trait in the population of fecal and clinical isolates of enterococci. The prevalence of anti-cytokine activity against tumor necrosis factor among enterococci of intestinal origin was noted, while Enterococcus spp. cultures, capable of degrading / binding interleukin-10 dominated among clinical isolates. The results obtained do not only expand the understanding of the immunomodulatory and anti-inflammatory functions of the symbiotic enterococci of the intestinal biotope, but can also be used to differentiate bacteria of the genus Enterococcus into symbiotic and etiologically significant strains.
CHARACTERISTICS OF PHYSICAL AND MECHANICAL PROPERTIES OF SHEEPSKIN OF LAMB RAISED IN THE REPUBLIC OF BURYATIA
Authors: Дармаева Виктория Гунгажаповна , Жамьянов Баир Валерьевич , Ачитуев Владимир Александрович , Жилякова Галина Максимовна 
Published: August 2024

В статье дана характеристика физико-механических свойств овчин молодняка овец бурятского типа забайкальской тонкорунной породы, бурятской полугрубошерстной и бурятской грубошерстной пород в возрасте 7 месяцев. По нашим данным площадь овчин, так же как и масса, варьирует в зависимости от породы. Наибольшей массой парной шкуры характеризуется молодняк бурятской полугрубошерстной и бурятского типа забайкальской тонкорунной породы. Так, их меховые овчины весят 3,51 кг и 3,45 кг против шубной овчины 3,03 кг, или на 12,2 % меньше. Наибольшая площадь овчин была у валушков грубошерстной породы - 113,36 м, что больше, чем у забайкальской тонкорунной, на 17,2 % и больше площади овчин у полугрубошерстных валушков на 4,1%. Овчины молодняка подопытных овец отличались и по физико-механическим свойствам. Лучшие качества по прочности кожевенной ткани отмечены у полугрубошерстных валушков. В целом, овчины животных разного происхождения соответствуют требованиям ГОСТ 4661-76 и ГОСТ 1821-75. Из полученных полуфабрикатов можно изготавливать как верхнюю одежду, головные уборы, так и постельные принадлежности - подушки, меховые одеяла, спальные мешки и чехлы на авто и автокресла, которые пользуются спросом у населения
The article describes physical and mechanical properties of sheep pelts of young sheep of Buryat type Transbaikal fine-wool breed, Buryat medium-wool breed and Buryat rough wool breed at the age of 7 months. According to our data, the area of sheepspelt, as well as the mass varies depending on the breed. Young Buryat medium-wool breed and Buryat type Transbaikal fine-wool breed is characterized by the greatest mass of pair skin. So, their wooled sheepskins weigh 3.51 kg and 3.45 kg against a pelts 3.03 kg, or the less 12.2%. The largest sheepskin surface of lamb rough wool breed was 113.36 m, which is more than Transbaikal fine-wool breed to 17.2% and more than the surface of sheep pelts in lamb medium-wool breed to 4.1%. The sheep pelt of young experimental sheep also differed in physical and mechanical properties. The best qualities the strength of leather fabric are noted in the lamb medium-wool breed. In general, sheep pelt of animals of different origins meet the requirements of GOST 4661-76 and GOST 1821-75. From the obtained semi-processed products it is possible to produce both surcoats, head wear, and bedclothes - pillows, sherpa throw, buntings and car covers and chair covers, which are in demand among the population.