bluuebunny/crossref_metadata_2025_split huggingface dataset:
Poster 351: Influence of Injury to the Kaplan Fibers and Anterolateral Ligament on Anterolateral Rotatory Knee Laxity in Adult and Pediatric Patients with Anterior Cruciate Ligament Injury: A Retrospective Cohort Study
Authors: Cui Jiaming 
Published: August 2024

Objectives: To detect concomitant Kaplan fibers (KF) and anterolateral ligament (ALL) injury in knees with anterior cruciate ligament (ACL) injury using magnetic resonance imaging (MRI) in both adult and pediatric patients and compare the effect of KF injury and multiple risk factors (concomitant injury to the ALL, medial collateral ligament [MCL], or anterior, central, or posterior part of the medial or lateral meniscus) on anterolateral rotatory laxity as measured by the pivot-shift test in a clinical setting. Methods: The study included 540 patients with primary ACL tears (71 pediatric patients and 469 adults) whose MRI examination and pivot-shift test were conducted within 14 days after injury. KF and ALL injury were assessed by MRI according to previously reported criteria. At the time of ACL reconstruction, the pivot-shift test was performed manually with the patient under anesthesia. Manual grading of the pivot shift was performed according to guidelines of the International Knee Documentation Committee (IKDC). Data were statistically compared between the adult and pediatric groups using the chi-square test and Fisher’s exact test (p < 0.05). Results:  Logistic regression analysis with backward elimination was used to identify risk factors associated with a high-grade pivot shift. Of the 12 initially included predictive variables, only four significantly increased the risk of a high-grade pivot shift: sex (odds ratio: 2.268 in total and 2.248 in adults), ALL disruption (odds ratio: 0.488 in total and 0.445 in adults), KF injury (odds ratio: 0.193 in pediatric patients), and injury to the posterior horn of the lateral meniscus (odds ratio: 0.545 in total and 0.559 in adults). Logistic regression analysis with backward elimination was also used to identify risk factors associated with KF injury. Of the 3 initially included predictive variables, 2 significantly increased the risk of KF injury: ALL injury (odds ratio: 0.271 in total and 0.206 in adults) and ALL disruption (odds ratio 0.267 in pediatric patients, odds ratio 0.580 in adults and 0.552 in total). Conclusions: Concomitant KF injury significantly affects the pivot-shift phenomenon in pediatric patients with acute ACL injury. These findings suggest that KFs may play an important role in controlling anterolateral rotatory knee laxity in pediatric patients.
Poster 395: Long Term Outcomes of Fasciotomy for Chronic Exertional Compartment Syndrome
Authors: Moore Michael , Lezak Bradley , Buldo-Licciardi Michael , Hughes Andrew , Wolfe Isabel , Seidenberg Julian , Jazrawi Laith 
Published: August 2024

Objectives: Operative treatment of Chronic Exertional Compartment Syndrome (CECS) with fasciotomy has been shown to be effective in symptomatic resolution of CECS, but outcomes at long term follow-up are not well understood. The purpose of this study is to present the long-term outcomes for CECS patients treated with fasciotomy. Methods: We conducted a retrospective review of patients who underwent fasciotomy of one or more compartments for treatment of CECS at our institution from 2010 to 2021. Outcomes were assessed using the Tegner Activity Scale, symptom resolution, patient satisfaction, return to sports (RTS) and the EuroQol (EQ-5D-5L) survey. Statistical analysis was completed using SPSS, Version 24 (IBM Corp., Armonk, NY). Normally distributed continuous variables between cohorts were compared using the two-sample Student t-test. Results: Thirty-four patients, 16 males and 18 females, who underwent open fasciotomy for CECS were included. Mean age at the time of surgery was 29.6 ±12.7 years and mean follow-up was 6.1 ±2.2 years (range 2.5-10.3). Tegner activity level scores at final follow up were significantly higher compared to scores at symptom onset (mean: 4.8 vs. 3.3, p<0.001). Regression analyses showed EQ-5D-5L scores were significantly associated with a post-operative diagnosis of popliteal artery entrapment syndrome (β=-0.135, p=0.023) and increased pre-operative symptom duration (β=-0.0003, p=0.043). 28/34 (82.3%) reported improved symptoms following fasciotomy, 5 (14.7%) reported no change, and 1 (2.9%) had worsened symptoms. Of those with improved symptoms, 19/28 (67.9%) reported complete symptom resolution. Twenty-six (76.5%) patients returned to sport and of these patients, 18/26 (69.2%) returned to their preinjury level. The average time to return to sport was 23.4±27.4 months. Of the 20 patients who worked prior to surgery, 18 (90.0%) returned to their pre-injury level and average time to return to work was 6.5±12.5 months. Twenty-four (70.6%) patients would be willing to have their fasciotomy again and average VAS satisfaction rate was 78.1. Conclusions: Pre-operative symptom duration and post-operative diagnosis of popliteal artery entrapment syndrome were poor prognostic indicators for patients diagnosed with CECS following fasciotomy at long term follow up. Tegner scores significantly improved at final follow up and the majority of patients returned to sport and work.
Gender Bias and Perceptions of the Nursing Profession in Croatia: A Cross-Sectional Study Comparing Patients and the General Population
Authors: Neuberg Marijana , Sopić Danijela , Košanski Tina , Grabant Mateja Križaj , Ribić Rosana , Meštrović Tomislav 
Published: August 2024

Background The way the nursing profession is perceived plays a pivotal role in shaping the public's attitude toward its members, primarily influenced by interactions with nurses and media representation. However, it can be significantly impacted by historical and traditional stereotypes, coupled with enduring gender bias and other preconceived notions. Objectives The study aimed to examined how the title “nurse” reflects the profession's identity, perception as a female occupation, and status as a healthcare activity. It also assessed awareness of nurses’ roles, education and public presence, comparing general population and patients’ opinions in the Republic of Croatia. Methods Conducted as a cross-sectional study, this research employed a structured questionnaire and a convenience sampling approach. It encompassed both the general population and patients from Croatia, with data collection spanning from February 15, 2023, to March 16, 2023, and resulting in a total sample size of 624 participants. Statistical analysis included both descriptive and inferential techniques, and significance was set at p < .01 (two-tailed). Results A substantial proportion of respondents, amounting to 38.1%, correlate the term “nurse” with the role of the physician's assistant, whereas only 49.5% associate it with a true professional functioning within their field of work. Furthermore, 73.7% study participants perceive the nursing profession as being desirable for men. Upon examining the perspectives of the general population and patients, statistically significant differences emerged in terms of their perceptions regarding the perceived work scope ( p < .001) and the level of sufficient educational attainment ( p < .001) of nursing professionals. Conclusion The analysis uncovers varying perceptions of the nursing profession in the Republic of Croatia, as well as evolving perceptions of gender diversity within nursing roles. Differing viewpoints between the general population and patients in this study emphasize the need for tailored education and communication initiatives to improve the image of nursing.
Supervisory Alliance in Medical Training: Associations with Educational Engagement and Satisfaction
Authors: Terry Danielle L. , Sehrish Laraib 
Published: August 2024

Objectives While medical education requires frequent interactions with attending physicians and supervisors, little research has explored the role of supervisory alliance in the learning process. In other learning environments, supervisory alliance, or the bond between a supervisor and trainee, is considered a key ingredient of effective supervision. Medical educators or attending physicians who aim to enhance learning and engagement in medical education may benefit from understanding specific factors that increase or decrease engagement and how those might intersect within a context that requires learning through supervision. This cross-sectional study examined associations between supervisory alliance and (a) program satisfaction, (b) educational engagement, (c) and career purpose. Methods Participants were medical trainees from the rural Northeast (n = 108, response rate = 81%) who completed an electronic and anonymous survey. Results Multiple linear regression was used to examine whether total supervisory alliance independently predicted behavioral and emotional engagement in learning while controlling for hours slept, hours worked, and burnout. Supervisory alliance predicted trainees’ career purpose, program satisfaction, and emotional engagement in learning. Conclusions Findings from this study lay groundwork for consideration of the role of supervisory alliance in medical learning processes. Future research might explore whether targeted mentorship programs or faculty enhancement training that focuses on the supervisory relationship might positively impact learning outcomes.
Co-localization of NCCT hypodensity and CTA spot sign predicts substantial intracerebral hematoma expansion: The Black-&-White sign
Authors: Pensato Umberto , Tanaka Koji , Horn MacKenzie , Teleg Ericka , Al Sultan Abdulaziz Sulaiman , Kasickova Linda , Ohara Tomoyuki , Ojha Piyush , Marzoughi Sina , Banerjee Ankur , Kulkarni Girish , Dowlatshahi Dar , Goyal Mayank , Menon Bijoy K. , Demchuk Andrew M. 
Published: August 2024

Background: Existing radiological markers of hematoma expansion (HE) show modest predictive accuracy. We aim to investigate a novel radiological marker that co-localizes findings from non-contrast CT (NCCT) and CT angiography (CTA) to predict HE. Methods: Consecutive acute intracerebral hemorrhage patients admitted at Foothills Medical Centre in Calgary, Canada, were included. The Black-&-White sign was defined as any visually identified spot sign on CTA co-localized with a hypodensity sign on the corresponding NCCT. The primary outcome was hematoma expansion (⩾6 mL or ⩾33%). Secondary outcomes included absolute (<3, 3–6, 6–12, ⩾12 mL) and relative (0%, <25%, 25%–50%, 50%–75%, or >75%) hematoma growth scales. Results: Two-hundred patients were included, with 50 (25%) experiencing HE. Forty-four (22%) showed the spot sign, 69 (34.5%) the hypodensity sign, and 14 (7%) co-localized both as the Black-&-White sign. Those with the Black-&-White sign had higher proportions of HE (100% vs 19.4%, p < 0.001), greater absolute hematoma growth (23.37 mL (IQR = 15.41–30.27) vs 0 mL (IQR = 0–2.39), p < 0.001) and relative hematoma growth (120% (IQR = 49–192) vs 0% (0–15%), p < 0.001). The Black-&-White sign had a specificity of 100% (95%CI = 97.6%–100%), a positive predictive value of 100% (95%CI = 76.8%–100%), and an overall accuracy of 82% (95%CI = 76%–87.1%). Among the 14 patients with the Black-&-White sign, 13 showed an absolute hematoma growth ⩾12 mL, and 10 experienced a HE exceeding 75% of the initial volume. The inter-rater agreement was excellent (kappa coefficient = 0.84). Conclusion: The Black-&-White sign is a robust predictor of hematoma expansion occurrence and severity, yet further validation is needed to confirm these compelling findings.
Living in Marooned Island: Growing Old as Gay Men
Authors: Roy Himadri 
Published: August 2024

Growing old is related with all human beings, but for those whose sexualities do not follow the social normative structure of family, growing old is more related to loneliness. This article will refer to such people with a different sexual orientation, in this case, mainly gay men. It will deal with the qualitative queer methodologies used for this particular topic. Queer gerontology has hardly been dealt with anywhere in research in this country; talking about old gay men seems to many that it does not need any methodology to deal with. But when academics try to investigate, interpret and interject many subjects and various areas, it is seen that the ‘queering communications’, ‘queer conversations’ and ’queer(y)ing ethics’ in qualitative methodology are always considered as similar as any social sciences qualitative methodology, or specifically gender qualitative methodology. This article will try to critically analyse how normative gerontology is very different from queer gerontology. This article includes a sample of 50 gay men in five different categories based on age: 30–35, 35–40, 40–45, 45–50 and 50–55 years. The sample includes gay men from different social and cultural backgrounds, various professional fields and several regions and languages, focusing mainly on people, power and place. Beside these, it will also have two broad categories: one who stays single and one who stays with a partner. Being a gay man brings lots of packages along with life—discrimination, violence, rights and privileges as a citizen of India are some of them that this article will also deal with. This article will try to bring the queer methodological structure into focus with the area of growing old gay men in a society where the socio-legal conditions consider them as criminals. The socio-psychological aloofness begins at an early age, and as one grows older, it corrugates the lives of such gay men as lonely, abhorrent human beings in society.
Addressing financial hardship in malignant hematology and hematopoietic cell transplant: a team approach
Authors: Jones Salene M. W. , Ohlsen Timothy J. D. , Karvonen Kristine A. , Sorror Mohamed 
Published: August 2024

Abstract
Financial hardship is a common experience for patients and their families after the diagnosis of a hematologic malignancy and is associated with worse outcomes. Health care costs, increased costs of living, income poverty, and inadequate wealth contribute to financial hardship after the diagnosis and treatment of a hematologic malignancy and/or hematopoietic cell transplant. Given the multidimensional nature of financial hardship, a multidisciplinary team-based approach is needed to address this public health hazard. Hematologists and oncologists may mitigate the impact of financial hardship by matching treatment options with patient goals of care and reducing symptom burden disruptive to employment. Social workers and financial navigators can assist with screening and resource deployment. Policymakers and researchers can identify structural and policy changes to prevent financial hardship. By alleviating this major health care burden from patients, care teams may improve survival and quality of life for patients with hematologic malignancies.
Association between a recalled positive airway pressure device and incident cancer: a population-based study
Authors: Kendzerska Tetyana , Pendharkar Sachin R. , Talarico Robert , Blades Kenneth , Mackenzie Constance , Gershon Andrea S. , Ayas Najib , Kaminska Marta , Fenton Mark , McBrien Kerry A. , Hawken Steven , Ratycz Diana , Lishchenko Vadym , Owens Robert L. , Povitz Marcus 
Published: August 2024

BackgroundThe real-world consequences of a Philips Respironics recall for positive airway pressure (PAP) devices distributed between 2009 and 2021 are unknown.MethodsWe conducted a retrospective population-based study using health administrative databases (Ontario, Canada) on all new adult PAP users identified through the provincial funding system, free of cancer at baseline, who initiated (claimed) PAP treatment between 2012 and 2018. Everyone was followed from the PAP claim date to the earliest of incident cancer diagnosis, death or end of follow-up (March 2022). We used inverse probability of treatment weighting to balance baseline characteristics between individuals on recalled devices and those on devices from other manufacturers. Weighted hazard ratios of incident cancer were compared between groups.ResultsOf 231 692 individuals identified, 58 204 (25.1%) claimed recalled devices and 173 488 (74.9%) claimed devices from other manufacturers. A meaningful baseline difference between groups (standardised difference ≥0.10) was noted only by location-relevant covariates; other variables were mostly equally distributed (standardised differences ≤0.06). Over a median (interquartile range) follow-up of 6.3 (4.9–8.0) years, 11 166 (4.8%) developed cancer: unadjusted rates per 10 000 person-years of 78.8 (95% CI 76.0–81.7) in the recall groupversus74.0 (95% CI 72.4–75.6) in others (p=0.0034). Propensity score weighting achieved excellent balance in baseline characteristics between groups (standardised differences ≤0.07). On a weighted sample, there was no statistical difference in the hazard of incident cancer between groups: cause-specific hazard ratio (recalledversusothers) 0.97 (95% CI 0.89–1.06).ConclusionIn our real-world population study, compared to other manufacturers and adjusting for confounders, recalled Philips Respironics PAP devices do not appear to be independently associated with developing cancer.
Exacerbation history and blood eosinophil count prior to diagnosis of COPD and risk of subsequent exacerbations
Authors: Halpin David M.G. , Healey Heath , Skinner Derek , Carter Victoria , Pullen Rachel , Price David 
Published: August 2024

BackgroundPrior exacerbation history is used to guide initial maintenance therapy in COPD; however, the recommendations were derived from patients already diagnosed and treated.MethodsWe assessed the rates of moderate (i.e.treated with antibiotics and/or systemic corticosteroids) and severe (i.e.hospitalised) exacerbations in the year following diagnosis in patients newly diagnosed with COPD according to their prior history of exacerbations, blood eosinophil count (BEC) and whether maintenance therapy was started. Data were extracted from the Optimum Patient Care Research Database.Results73 189 patients were included. 61.9% had no exacerbations prior to diagnosis, 21.5% had 1 moderate, 16.5% had ≥2 moderate and 0.3% had ≥1 severe. 50% were started on maintenance therapy. In patients not started on maintenance therapy the rates of moderate exacerbations in the year after diagnosis in patients with no, 1 moderate, ≥2 moderate and ≥1 severe prior exacerbations were 0.34 (95% CI 0.33–0.35), 0.59 (95% CI 0.56–0.61), 1.18 (95% CI 1.14–1.23) and 1.21 (95% CI 0.73–1.69), respectively. Similar results were seen in patients started on maintenance therapy. BEC did not add significantly to the prediction of future exacerbation risk.ConclusionsA single moderate exacerbation in the year prior to diagnosis increases the risk of subsequent exacerbations, and more frequent or severe exacerbations prior to diagnosis are associated with a higher risk.
A computationally feasible multi-trait single-step genomic prediction model with trait-specific marker weights
Authors: Strandén Ismo , Jenko Janez 
Published: August 2024

Abstract
Background
Regions of genome-wide marker data may have differing influences on the evaluated traits. This can be reflected in the genomic models by assigning different weights to the markers, which can enhance the accuracy of genomic prediction. However, the standard multi-trait single-step genomic evaluation model can be computationally infeasible when the traits are allowed to have different marker weights.

Results
In this study, we developed and implemented a multi-trait single-step single nucleotide polymorphism best linear unbiased prediction (SNPBLUP) model for large genomic data evaluations that allows for the use of precomputed trait-specific marker weights. The modifications to the standard single-step SNPBLUP model were minor and did not significantly increase the preprocessing workload. The model was tested using simulated data and marker weights precomputed using BayesA. Based on the results, memory requirements and computing time per iteration slightly increased compared to the standard single-step model without weights. Moreover, convergence of the model was slower when using marker weights, which resulted in longer total computing time. The use of marker weights, however, improved prediction accuracy.

Conclusions
We investigated a single-step SNPBLUP model that can be used to accommodate trait-specific marker weights. The marker-weighted single-step model improved prediction accuracy. The approach can be used for large genomic data evaluations using precomputed marker weights.
The costs and benefits of symbiotic interactions: variable effects of rhizobia and arbuscular mycorrhizae on Vigna radiata accessions
Authors: Chien Chih-Cheng , Tien Shang-Ying , Yang Shu-Yi , Lee Cheng-Ruei 
Published: August 2024

Abstract
Background
The symbiosis among plants, rhizobia, and arbuscular mycorrhizal fungi (AMF) is one of the most well-known symbiotic relationships in nature. However, it is still unclear how bilateral/tripartite symbiosis works under resource-limited conditions and the diverse genetic backgrounds of the host.

Results
Using a full factorial design, we manipulated mungbean accessions/subspecies, rhizobia, and AMF to test their effects on each other. Rhizobia functions as a typical facilitator by increasing plant nitrogen content, plant weight, chlorophyll content, and AMF colonization. In contrast, AMF resulted in a tradeoff in plants (reducing biomass for phosphorus acquisition) and behaved as a competitor in reducing rhizobia fitness (nodule weight). Plant genotype did not have a significant effect on AMF fitness, but different mungbean accessions had distinct rhizobia affinities. In contrast to previous studies, the positive relationship between plant and rhizobia fitness was attenuated in the presence of AMF, with wild mungbean being more responsive to the beneficial effect of rhizobia and attenuation by AMF.

Conclusions
We showed that this complex tripartite relationship does not unconditionally benefit all parties. Moreover, rhizobia species and host genetic background affect the symbiotic relationship significantly. This study provides a new opportunity to re-evaluate the relationships between legume plants and their symbiotic partners.