bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association of Fibroblast Growth Factor-1 Promoter Polymorphism and its Serum Concentrations with Repeated Implantation Failure after In vitro Fertilisation: A Cross-sectional Study
Authors: Kharamani Afshin , Mashayekhi Farhad , Salehi Zivar 
Published: June 2024

ABSTRACT

Background:
Fibroblast growth factors (FGFs) play a key role in embryo implantation and support endometrial trophoblastic interaction.

Aim:
The aim of the study was to evaluate the association between FGF-1 (rs34011) gene variety and its serum concentration with repeated implantation failure (RIF).

Setting and Design:
The design of the study was a cross-sectional study.

Materials and Methods:
Four hundred infertile women with a history of RIF and 400 healthy women undergoing the first in vitro fertilisation-embryo transfer attempt with successful delivery (controls) were enrolled in the study. Genomic DNA was extracted from peripheral blood leucocytes and genotyped by Tetra-Primer Amplification Refractory Mutation System-Polymerase Chain Reaction. Serum FGF-1 concentration was evaluated with enzyme-linked immunosorbent assay.

Statistical Analysis Used:
The ANOVA test was used to analyse the difference between the means of the groups.

Results:
In RIF group, the genotype frequencies of the GG, GA and AA were 59%, 33.5% and 7.5%, respectively, whereas in controls were 72.5%, 24% and 3.5%, respectively. The G and A allele frequencies in the RIF group were 75.75% and 24.25%, while in controls were 84.5% and 15.5%, respectively (P < 0.0001). We have also shown that serum FGF-1 concentration in RIF and control groups was 17 ± 3.55 and 23.62 ± 4.91 pg/mL, respectively (P = 0.008). We have also shown that AA genotype is significantly associated with decreased serum FGF-1 concentration in RIF (AA, GA and GG serum levels were 9.55 ± 2.65, 14 ± 3.35 and 22.55 ± 7.26 pg/mL, and in controls were 12.22 ± 2.27, 18.44 ± 5.98 and 26.66 ± 8.29 pg/mL, respectively).

Conclusion:
The current study suggests that a significant association between FGF-1 (rs34011) promoter polymorphism and its serum concentration with RIF. The study also suggests that AA genotype is linked to lower FGF-1 serum levels and may play a risk factor for RIF.
Effect of Incorporating Chitosan to Resin Modified Glass Ionomer Cement on Shear Bond Strength to Dentin (An In vitro Comparative Study)
Authors: Khudhair Aya Tahseen , Khalaf Muna Saleem 
Published: June 2024

Abstract

Aim:
Resin-modified glass ionomer cement tends to shrink due to polymerization of the resin component. Additionally, they are more prone to syneresis and imbibition during the setting process. This in vitro study evaluates the impact of chitosan, a biopolymer that is, both biomaterial and biocompatible, on the strength of dentin bonding and compares it with ACTIVA Bio-ACTIVE Restorative. The present study was aimed to assess the impact of including chitosan into Fuji II on the shear bond strength between. the restoration material and tooth dentin, in contrast to Bioactiva in permanent teeth.

Materials and Methods:
A total of 30 premolar teeth were recently extracted. The study involved three distinct sample groups. Group 1 (10 teeth) is the negative control (Fuji II), Group 2 (10 teeth) is the positive control (ACTIVA Bio-ACTIVE Restorative), and Group 3 (10 teeth) is treated with a mixture of Chitosan and Fuji II (CH-Fuji II). Each tooth’s buccal and palatal cusps were eliminated to achieve a horizontal surface. Using a periodontal probe, 1.5 mm from the mesial pit to the mesial marginal ridge were removed. Restoration was implemented in all groups following manufacturer directions. Thermocycling the teeth by immersing them in a water bath with temperatures ranging from 5°C to 55°C (± 1–2°C) for 30 s (500 cycles). Each sample was attached to the universal testing machine’s jig at a cross-head speed of 1 mm/min. Shear force was used until breakage, and the bond’s adhesive strength was then calculated. Statistical analysis using ANOVA with Dunnett’s T3 post hoc test. Results were significant at P < 0.05.

Results:
Statistically significant difference was present between Chitosan and Fuji II and between Chitosan and Activa by reducing the shear bond strength.

Conclusions:
Addition of chitosan to Fuji II had a negative effect on the shear bond with a significant difference while Activa and Fuji II exhibited favorable shear bond strength.
Weight loss following lifestyle modification interventions among adults with overweight and obesity in low- and middle-income countries – A systematic review and meta-analysis protocol
Authors: Patel Namita , Menon Athira , Aiswariya J. S. , Loganathan Vignesh , Lakshminarayanan Subitha 
Published: June 2024

Introduction:
Overweight and obesity have become complex public health issues affecting all age, gender, and socioeconomic groups. It is a significant risk factor for various noncommunicable diseases such as hypertension, liver and kidney disease, diabetes, cardiovascular diseases, and depression. Despite this, obesity screening, prevention, and treatment are insufficiently focused in the health systems in low- and middle-income countries. There is a need for targeted interventions that are more realistic, applicable to all population groups, and have the potential for higher success rates. With this idea in mind, the current review has focused on systematically gathering evidence on the effect of weight management interventions compared to the standard of care among adults with overweight and obesity from low- and middle-income countries.

Methodology:
We will systematically search four electronic databases – PubMed, Google Scholar, Embase, and the Cochrane Library from their inception until July 2023 for relevant studies. A combination of medical subject headings and free text terms will be used for carrying out literature searches. All the experimental studies randomized controlled trials or nonrandomized trials conducted in a clinic-, hospital-, or community-based setting will be included in our review. Studies conducted among adults aged 18 years and above with overweight or obesity with nonpharmacological weight management given as intervention and standard of care given as comparator will be looked for. The outcome measures include the standardized mean difference of weight, body mass index, waist or hip circumference, or odds ratio of obesity or overweight between the treatment groups. Meta-regression or subgroup analyses will be performed to explore the heterogeneity. The Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines will be used to report the review.

Study Design:
Systematic review and meta-analysis.

Ethics and Dissemination:
There are no ethical concerns about the conduct of this review. Evidence will be disseminated at relevant conferences and by submitting scientific articles to academic peer-reviewed journals.

Conclusion:
Findings from this systematic review will significantly contribute to enhancing knowledge about evidence of the effectiveness of various obesity management strategies. This evidence-based approach will guide informed decision-making processes and support the development of effective interventions or programs to address the obesity epidemic in low- and middle-income countries.

Prospero Registration:
CRD42022352118.
Postoperative analgesic effect of adding neostigmine to levobupivacaine in ultrasound-guided spermatic cord block for testicular sperm extraction surgery
Authors: Wahdan Amr Samir , Moussa Ahmed Abdelhady , Farag Mohamed Abdel Fattah , Alayyaf Hasan Abdullah , Mohamed Mennatallah Magdi 
Published: June 2024

Abstract

Background and Aims:
Providing postoperative pain management in patients who underwent scrotal surgeries is achieved using several methods, one of which is the ultrasound-guided spermatic cord block (US-SCB). To enhance anesthesia quality and extend analgesia postoperatively, several agents have been added in conjunction with local agents. This study targeted assessing the results of combining neostigmine with levobupivacaine in US-SCB for providing perioperative analgesia in patients undergoing testicular sperm extraction (TESE) surgery.

Material and Methods:
This double-blind, randomized controlled study was performed for 112 subjects undergoing TESE operation using general anesthesia. They were randomly and equally divided into two groups. All participants received bilateral US-SCB after induction of general anesthesia by 19 mL of levobupivacaine 0.5% combined with 1 mL of neostigmine 500 μg in (group N) or 1 mL of normal saline in (group C). The first analgesic dose request time and the amount of analgesic consumed in the first 24 h were the main points of comparison in both groups.

Results:
The mean postoperative analgesia duration was noticeably increased in the N group compared to the C group, with a value of 480 ± 41.34 min versus 404 ± 34.14 min, independently (P < 0.001). Moreover, the total amount of postoperative analgesic consumption was remarkably decreased in group N when compared to group C without statistically remarkable divergence concerning complications between both groups.

Conclusion:
Adding neostigmine to a local anesthetic solution in US-SCB proved to detain the first analgesic request postoperatively with reduced perioperative analgesia consumption, without significant side effects.
Insights into pathophysiology, management, and outcomes of near-hanging patients: A narrative review
Authors: Kannamani Balaji , Sahni Neeru , Bandyopadhyay Anjishnujit , Saini Vikas , Yaddanapudi Laxmi Narayana 
Published: June 2024

Abstract
Hanging is suspension of a person by noose or ligature around the neck. Hanging has been used as a judicial execution method since medieval times and is still a common method of suicide in developing countries. The term “near hanging” is used for those who survive long enough to reach the hospital, and these patients still hold mortality as high as 45%. These patients can present with a wide array of complaints involving cardiovascular, neurologic, and pulmonary systems and local injuries to the airway and vascular structures. High serum lactate and cardiac arrest at arrival are some of the prognostic factors which portend a poor prognosis. Early admission and aggressive treatment are essential to provide best neurologic outcome. Due to paucity of definitive guidelines, therapy has to be based on clinical reports and expertise of the treating physician. Hence, near-hanging patients pose a great challenge in primary emergency care and intensive care management. This review aims to outline the pathophysiology, prognostic indicators, and recent evidence in the management of near-hanging patients.
A randomised controlled trial to compare tracheal extubation quality in lateral and supine positions after general anaesthesia in children
Authors: Ganigara Anuradha , Bhavana D. A , Chandrika Y. R , Sharma Trishi 
Published: June 2024

Abstract

Background and Aims:
Tracheal extubation after general anaesthesia in pediatrics is a critical event, with sparse research on positioning of patient during extubation. Clinical data reveal lesser airway obstruction in the lateral position with enhanced airway patency. We studied the effects of supine versus lateral positioning on the quality of tracheal extubation as judged by the modified Minogue cough score in children undergoing elective surgeries under general anaesthesia. Secondary objectives included frequency of incidences of oxygen desaturation (SPO2 <92%), laryngospasm, bronchospasm, and stridor.

Material and Methods:
In this single-blinded randomised trial, 110 children in the age group of 2–12 years were enrolled to be positioned in either the lateral (group L) or supine (group S) position during extubation at the end of surgery. All patients received a standardised anaesthesia regimen. Chin lift and positive pressure ventilation were instituted if airway patency was noted to be compromised during extubation. Vital parameters, extubation quality, sedation score, incidence of oxygen desaturation, laryngospasm, stridor, and bronchospasm were recorded every 5 minutes till 30 minutes post extubation.

Results:
Children in group S were noted to have a higher cough score at the 15th minute post extubation with a P value of 0.04 compared to children in group L. Children in group L had a 18% incidence of adverse respiratory events compared to 30% in group S with a relative risk of 1.67.

Conclusions:
Positioning children in the lateral position during extubation resulted in improved extubation quality as evidenced by lower cough scores with fewer incidence of complications in comparison to supine position extubation.
ACRCP -Protocol for Delay Tolerant Networks for Effective Green Computing Environment
Authors: Preetha V. , Balasubramanian K. 
Published: June 2024

There is no universally accepted definition of a green building. Generally, it refers to an ideal living environment created with respect for ecological principles and environmental considerations, combined with the principle of ecological design. Green buildings not only improve living conditions and energy efficiency but also contribute to urban air quality, enhance landscapes, and positively impact the physiological and psychological well-being of individuals. To achieve the goals of green building, it is imperative to have convenient and accurate selection of plant materials, create a sustainable green system, and establish a comprehensive green building plant resource information system.

Over the past few decades, numerous quantitative studies on the ecological functions of green plants have been conducted worldwide. Various test methods have been employed under different green conditions to quantify these functions and obtain numerous quantitative values. Concepts such as green area, green coverage, leaf area index, leaf area, green rate, vertical green coverage area, and overall green quantity have been introduced. Delay Tolerant Network (DTN) engineering faces challenges in ensuring end-to-end availability in cloud computing. Consequently, transporting data over such networks is challenging since most Internet applications rely on persistent end-to-end connections. Since the standardization of the DTN architecture, significant research has been dedicated to developing routing protocols for various mobility scenarios, aiming to improve segment delay, delivery, and data delivery ratios.
Cosmologías en abundancia para las artes y el diseño
Authors: Moscoso Mafe , Moncunill-Piñas Mariona 
Published: June 2024

El presente número reúne artículos de investigación artística y en diseño así como proyectos experimentales que tienen en cuenta, se dejan atravesar por, investigan o surgen desde cosmologías y ontologías que desbordan aquellas en las que se inscribe tradicionalmente el pensamiento académico occidental.
Se incluyen tres artículos en nuestra sección de Artículos originales, uno en la sección de Proyectos y una reseña de libro.
PERCEPÇÃO DOS RESULTADOS COM A PRÁTICA DE MUSCULAÇÃO
Authors: Gonçalves Schmidt de Paula Janaina , Marques da Silva Júnior Francisco , Lucy da Silva Rosa Grazielle , Roberto de Matos e Ávila Waldney , Mendes Amaral Giovanna , Lafetá Jean Claude , Veloso Rocha Marinho Hellen 
Published: June 2024

O presente estudo teve como objetivo verificar a percepção dos resultados obtidos com a prática de musculação. A amostra foi composta por 256 indivíduos, de ambos os sexos, com idade média de 30,94 ± 9,60 anos, sendo 134 masculino e 122 feminino. Os participantes responderam um formulário contendo questões relacionadas aos objetivos do presente estudo. Foi utilizado o teste qui-quadrado para comparar, entre sexos, os objetivos e a percepção dos resultados obtidos, considerando um nível de significância α ≤ 0,05. Foi evidenciado que entre os objetivos avaliados, hipertrofia muscular foi o resultado percebido pelo maior percentual de participantes, seguido por condicionamento físico, emagrecimento e definição muscular. Além disso, destaca-se que 99,61% relataram melhora com relação aos objetivos almejados com a prática da musculação. Foi evidenciada diferença entre os sexos na percepção dos resultados obtidos para hipertrofia e aumento de força musculares, sendo que a maioria do homens informaram melhora completa para hipertrofia muscular e todos os homens que relataram ter como objetivo aumento de força muscular informaram ter alcançado seus objetivos. Não houveram diferenças entre os sexos quanto a percepção dos resultados para condicionamento físico, emagrecimento, definição muscular e outros. Conclui-se que os principais objetivos para de musculação foram hipertrofia muscular, condicionamento físico e emagrecimento. A maioria relatou melhora parcial com a prática da musculação. Houve maior proporção de homens informando ter como meta hipertrofia muscular, enquanto que houve maior frequência mulheres que tinham como objetivo definição muscular e emagrecimento. A maioria do homens relataram melhora completa em relação à hipertrofia muscular e todos os homens que informaram ter como objetivo o aumento de força muscular reportaram melhora completa nessa capacidade.
A IMPORTÂNCIA DA EDUCAÇÃO FÍSICA ESCOLAR NA FORMAÇÃO DO INDIVÍDUO
Authors: Souto Alenice Ferraz , Alves Caribe Cunha Alexandre , Ferraz Amaral Josária 
Published: June 2024

RESUMO
Faz-se necessário o reconhecimento da importância e a valorização da disciplina Educação Física na formação básica. Assim, este estudo teve como objetivo revisar a literatura sobre as contribuições da disciplina Educação Física no processo da formação integral dos educandos. Buscou-se investigar os conteúdos dessa disciplina e as possibilidades de intervenção didático-pedagógicas em prol da formação crítica, reflexiva, autônoma e cidadã das crianças e adolescentes na educação básica. A busca bibliográfica consistiu na pesquisa de artigos publicados entre os anos de 1981 e 2021, utilizando, de forma combinada, os descritores Educação Física, escola e formação. Após a análise dos títulos e dos resumos, 4 artigos, foram incluídos nesta revisão. A Educação Física como componente curricular, tem como pressuposto básico, disseminar conhecimento sistematizado sobre a cultura corporal de movimento, capacitando o educando para a regulação, interação e transformação em relação ao meio em que vive, contribuindo para a formação do sentido de ser humano.

Palavras-chave: Educação Física. Escola. Formação.
Genesis of philosophy: discursive practices
Authors: Ковыршина С.В. 
Published: June 2024

В статье анализируются различные подходы, концепции и позиции, касающиеся вопроса происхождения философии. Автор обращает внимание как на ставшие уже классическими подходы, так и на исследования современных авторов. Многообразие дискурсивных практик позиционирования философии позволяет говорить о моменте зарождения как своеобразном инварианте развития философской мысли. Акцентируется внимание на двух моментах: появлении термина «философия» и собственно возникновении философии как особой об- ласти человеческой жизнедеятельности. Принимая во внимание четыре основополагающие концепции происхождения философии, – мифогенную, гносеогенную, социогенную и софиогенную, появляется возможность обратить внимание на оригинальные позиции относительно времени и места ее появления. Таким образом, проблема генезиса философии – это создание не только множества онтологических моделей, но и трансляция определенных дискурсивных практик, связанных со спецификой мышления и отношением к окружающему миру.
The article analyzes various approaches, concepts and positions concerning the question of the origin of philosophy. The author draws attention both to the approaches that have already become classical and to the research of modern authors. The variety of discursive practices of philosophy positioning allows us to talk about the moment of origin as a kind of invariant for the development of philosophical thought. Attention is focused on two points: emergence of the term “philosophy” and actual emergence of philosophy as a special area of human activity. Taking into account 4 fundamental concepts of the origin of philosophy (mythogenic, epistemological, sociogenic and sophiogenic), it becomes possible to pay attention to original positions regarding the time and place of the appearance of philosophy. Thus, the philosophy genesis problem is not only the creation of a great number of ontological models, but also the translation of certain discursive practices related to the specifics of thinking and attitude to the world around us.
From the place of action to the space of meaning: Ch. Gungaasukh’s work and his role in the development of scenography art in Mongolia in the last third of the 20th century
Authors: Батхулэг Э. 
Published: June 2024

В статье рассматривается творческая деятельность выдающегося художника-сценографа, народного художника Ч. Гунгаасуха и анализируется его значительная роль в развитии театрально-декорационной живописи в Монголии XX века. Основу для их искусствоведческого изучения образует обширный изобразительный материал из фондов Театрального музея в Улан-Баторе, до сих еще в полной мере не известный специалистам. Анализ сохранившихся эскизов позволяет сделать вывод о том, что творчество Чойжылжавына Гунгаасуха сыграло определяющую роль в утверждении на монгольской сцене модернистских принципов декорационного решения, основу которых составило совершенно новое понимание задачи организации сценического пространства. Исследование показало, что использованные художественные приемы имели задачей усилить выразительный потенциал сценического оформления, превратив живописно-пластический образ в важнейший содержательный фактор театральной постановки. Кроме того, творчество Ч. Гунгаасуха сыграло ключевую роль в процессе утверждения на монгольской сцене 1970–1980-х годов национальной тематики, тем самым предвосхитив важнейшие тенденции в развитии современного монгольского искусства.
This article examines the creative activity of the outstanding artist and scenographer, People’s Artist Ch. Gungaasukh and analyses his great role in the development of theatrical and decorative art in Mongolia. The basis for this art-historical study is formed by the extensive material of art, which is kept in the Theatre Museum in Ulaanbaatar and is still not fully known to specialists. The throughout analysis of the sketches allows us to conclude that the work by Ch. Gungaasukh played a decisive role in the dissemination of the modernist principles in the sphere of the theatre decorative painting on Mongolian 20th century scene. These principles were based on the completely new understanding of the spatial organization of the scene. Their consideration gives us an opportunity to conclude that the artistic techniques used by Ch. Gungaasukh were intended to enhance the expressive potential of the stage design, turning the pictorial image into the most important meaningful factor of the theatrical performance. In addition, the work by this artist played a crucial role in the process of establishing the national subject matter on Mongolian scene of the 1970s and 1980s, thus anticipating the most important trends in the development of Mongolian modern art.