bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Synthesis of Bright Alkenyl‐1H‐1,2,4‐triazoles: A Theoretical and Photophysical Study.
Authors: Cebrian Cristina , de Mata Munoz Juan , Strassert Cristian Alejandro , Prieto Pilar , Diaz‐Ortiz Angel , De Cola Luisa , de la Hoz Antonio 
Published: March 2015

Abstractπ‐Conjugated title triazoles are synthesized in water under microwave irradiation with good yields.
ChemInform Abstract: Catalytic Oxidation of β‐Keto Esters by Manganese(III)/Cobalt(II) and Consecutive Cyclization to Heterocycles.
Authors: Ju Yeming , Miao Di , Seo Jeong Gil , Koo Sangho 
Published: March 2015

Abstractβ‐Keto esters are catalytically oxidized by Mn(III)/Co(II)‐system to α‐oxo esters, which directly cyclize to dihydropyrans or furans.
ChemInform Abstract: Combining Silver Catalysis and Organocatalysis: A Sequential Michael Addition/Hydroalkoxylation One‐Pot Approach to Annulated Coumarins.
Authors: Hack Daniel , Chauhan Pankaj , Deckers Kristina , Hermann Gary N. , Mertens Lucas , Raabe Gerhard , Enders Dieter 
Published: March 2015

AbstractBy merging primary amine catalysis with silver‐catalysis, a series of functionalized coumarin derivatives (III) and (V) is obtained in good yields and good to excellent enantioselectivities.
ChemInform Abstract: An Efficient and Green Synthesis of Flavones Using Natural Organic Acids as Promoter under Solvent‐Free Condition.
Authors: Thorat Nitin M. , Kote Santosh R. , Thopate Shankar R. 
Published: March 2015

AbstractNaturally occurring acids are used as environmentally‐friendly acid catalyst in the synthesis of flavones (II) by cyclodehydration of 1‐(2‐hydroxyphenyl)‐3‐aryl‐1,3‐propanediones (I).
ChemInform Abstract: Transition‐Metal‐Free Arylation of N‐Alkyl‐tetrahydroisoquinolines under Oxidative Conditions: A Convenient Synthesis of C1‐Arylated Tetrahydroisoquinoline Alkaloids.
Authors: Singh Kamal Nain , Kessar Satinder V. , Singh Paramjit , Singh Pushpinder , Kaur Manjot , Batra Aanchal 
Published: March 2015

AbstractThe method is applied to the synthesis of cryptostyline II (IXa) and cryptostyline III (IXb).
ChemInform Abstract: An Eco‐Friendly and Water Mediated Product Selective Synthesis of 2‐Aminopyrimidines and Their in vitro Antibacterial Evaluation.
Authors: Nagarajan Sangaraiah , Shanmugavelan Poovan , Sathishkumar Murugan , Selvi Ramasamy , Ponnuswamy Alagusundaram , Harikrishnan Hariharan , Shanmugaiah Vellasamy , Murugavel Saminathan 
Published: March 2015

AbstractThree of the synthesized compounds, i.e.
ChemInform Abstract: Electrochemical Synthesis of Potassium Aryltrifluoroborates.
Authors: Nascimento Wilson , Oliveira Jadson L. , Freitas Juliano C. R. , Navarro Marcelo , Menezes Paulo H. 
Published: March 2015

AbstractThe method is applied to the synthesis of compound (VI), a fragment of the natural product combretastatin D2.
ChemInform Abstract: Rapid Access to Benzoxaphospholes and Their Spiro Analogues by a Three‐Component Coupling Involving Arynes, Phosphines, and Activated Ketones.
Authors: Bhunia Anup , Roy Tony , Gonnade Rajesh G. , Biju Akkattu T. 
Published: March 2015

AbstractA multicomponent coupling reaction involving in situ generated arynes, phosphine (III) or arsine (V), as well as various acyclic and cyclic activated carbonyl compounds (II), (VII), and (IX) is described.
ChemInform Abstract: Silver‐Catalyzed Carbonphosphonation of α,α‐Diaryl Allylic Alcohols: Synthesis of β‐Aryl‐γ‐ketophosphonates.
Authors: Mi Xia , Wang Chenyang , Huang Mengmeng , Wu Yusheng , Wu Yangjie 
Published: March 2015

AbstractThe silver‐catalyzed radical reaction of phosphonate (II) with symmetrical α,α‐diaryl allylic alcohols (I) is accompanied by a 1,2‐migration of an aryl group to afford β‐aryl‐γ‐ketophosphonates (III).
ChemInform Abstract: Stereoselective Synthesis of Tricyclic Diproline Analogues that Mimic a PPII Helix: Structural Consequences of Ring‐Size Variation.
Authors: Soicke Arne , Reuter Cedric , Winter Matthias , Neudoerfl Joerg‐Martin , Schloerer Nils , Kuehne Ronald , Schmalz Hans‐Guenther 
Published: March 2015

AbstractSynthons (VI) and (Xb) are prepared and used in the peptide coupling with proline derivative (XI).
ChemInform Abstract: A General and Practical Palladium‐Catalyzed Monoarylation of β‐Methyl C(sp3)—H of Alanine.
Authors: Chen Kai , Zhang Shuo‐Qing , Xu Jing‐Wen , Hu Fang , Shi Bing‐Feng 
Published: March 2015

AbstractThe title reaction uses an 8‐aminoquinoline auxiliary as directing group and is compatible with a variety of functional groups with complete retention of chirality.
Bi2O3@Reduced Graphene Oxide Nanocomposite: An Anode Material for Sodium‐Ion Storage
Authors: Nithya Chandrasekaran 
Published: March 2015

AbstractThe high capacity, excellent cyclability, and good rate capability of reduced graphene oxide (rGO) anchored with Bi2O3 nanocomposite for sodium‐ion batteries is reported. A simple reduction method is adapted to deposit spherical Bi2O3 nanoparticles on the surface of rGO sheets. The surfactant cetyltrimethylammonium bromide (CTAB) plays a major role in controlling the morphology of the Bi2O3 nanoparticles. This Bi2O3@rGO nanocomposite has the advantages of high reversible capacity with a capacity retention (at high rate) of 70.2 % after 200 cycles at a current density of 350 mA g−1. This superior performance can be attributed to the fact that rGO sheets hamper the volume expansion of Bi2O3 nanoparticles and result in faster diffusion of Na+ ions (diffusion coefficient: 5.12×10−8 cm2 s−1) and smaller internal resistance (84.17 Ω) compared with pristine Bi2O3 nanoparticles. The results suggest that anchoring rGO sheets with metal oxides is one of the simplest ways to enhance the electrochemical performance of sodium‐ion batteries.
Development and evaluation of short forms of the Pain Catastrophizing Scale and the Pain Self‐efficacy Questionnaire
Authors: McWilliams L.A. , Kowal J. , Wilson K.G. 
Published: March 2015

AbstractBackgroundTo facilitate efficient screening and reduce the length of comprehensive self‐report batteries, a four‐item short form of the Pain Catastrophizing Scale (PCS) and a two‐item short form of the Pain Self‐Efficacy Questionnaire (PSEQ) have been developed and evaluated in samples of patients with arm and upper extremity pain.AimsThe first aim of this study was to evaluate these short forms in a heterogeneous sample of patients seeking treatment for chronic musculoskeletal pain, using a priori criteria for determining adequate internal consistency, construct validity and sensitivity to change. In addition, the findings of past studies were used to identify items suitable for new and potentially stronger short forms of these measures.MethodData were provided by 280 patients who completed the original PCS and PSEQ as part of an interdisciplinary rehabilitation programme.ResultsThe previously developed four‐item PCS and the newly developed six‐item short form of the PCS both met the internal consistency and construct validity criteria. They did not meet the criterion regarding sensitivity to change. However, similar to what was obtained using the original PCS, large effect sizes were found when using these short forms to examine pre‐treatment to post‐treatment changes in catastrophizing. For the PSEQ, the new four‐item short form was clearly superior to the other alternatives and met all three criteria.ConclusionThe strongest short forms of the PCS and PSEQ could facilitate the assessment of pain catastrophizing and self‐efficacy in situations in which the use of the longer original measures is not feasible.
Bootstrap Replacement to Validate the Influence of the Economic Cycle on the Structure and the Accuracy Level of Business Failure Prediction Models
Authors: Manzaneque Montserrat , GarcíA‐Pérez‐De‐Lema Domingo , Antón Renart Marcos 
Published: March 2015

AbstractThe aim of this study was to answer the question of how the economic cycle affects the stability and efficiency of business failure prediction models, using bootstrap replacement method for validation. We analyse 2228 Spanish small and medium‐sized enterprises for the period 2001–2009, and divide it into three different phases of the economic cycle (growth, crisis, recession). We find that the structure and the ability of business failure prediction models are different according to the economic cycle. These findings are relevant for the debate on the most suitable financial ratios when developing business failure prediction models and to pose their accuracy level in these prediction models. Copyright © 2015 John Wiley & Sons, Ltd.
Informal Care Motivations and Intergenerational Transfers in European Countries
Authors: Jiménez‐Martín Sergi , Vilaplana Prieto Cristina 
Published: March 2015

AbstractThis work sets out to analyze the motivations adult children may have to provide informal care, considering the monetary transfers they receive from their parents. Traditional motivations, such as altruism and exchange, are matched against more recent social bond theories. Our findings indicate that informal caregivers receive less frequent and less generous transfers than non‐caregivers; that is, caregivers are more prone to suppress their self‐interested motivations in order to prioritize the well being of another person. Additionally, long‐term public care benefits increase both the probability of receiving a transfer and its amount, with this effect being more intense for both the poorest and richest households. Our findings suggest that if long‐term care benefits are intended to increase the recipients' welfare and represent a higher fraction of total income for the poorest households, the effectiveness of these long‐term care policies may be diluted. Copyright © 2015 John Wiley & Sons, Ltd.
Practice Patterns among Entrants and Incumbents in the Home Health Market after the Prospective Payment System was Implemented
Authors: Kim Hyunjee , Norton Edward C. 
Published: March 2015

AbstractHome health care expenditures were the fastest growing part of Medicare from 2001–2009, despite the implementation of prospective payment. Prior research has shown that home health agencies adopted two specific strategies to take advantage of Medicare policies: provide at least 10 therapy visits to get an enormous marginal payment and recertify patients for additional episodes. We study whether there is heterogeneity in the adoption of those strategic behaviors between home health agency entrants and incumbents and find that entrants were more likely to adopt strategic practice patterns than were incumbents. We also find that for‐profit incumbents mimicked one of the practice patterns following entrants in the same market. Our findings suggest that it is important to understand the heterogeneity in providers' behavior and how firms interact with each other in the same market. These findings help explain the rapid rise in expenditures in the home health care market. Copyright © 2015 John Wiley & Sons, Ltd.
Local Variability in Long‐Term Care Services: Local Autonomy, Exogenous Influences and Policy Spillovers
Authors: Fernandez José‐Luis , Forder Julien 
Published: March 2015

AbstractIn many countries, public responsibility over the funding and provision of long‐term care services is held at the local level. In such systems, long‐term care provision is often characterised by significant local variability. Using a panel dataset of local authorities over the period 2002–2012, the paper investigates the underlying causes of variation in gross social care expenditure for older people in England. The analysis distinguishes between factors outside the direct control of policy makers, local preferences and local policy spillovers. The results indicate that local demand and supply factors, and to a much lesser extent local political preferences and spatial policy spillovers, explain a large majority of the observed variation in expenditure. Copyright © 2015 John Wiley & Sons, Ltd.
Acceptability of programme budgeting and marginal analysis as a tool for routine priority setting in Indigenous health
Authors: Otim Michael E. , Asante Augustine D. , Kelaher Margaret , Anderson Ian P. , Jan Stephen 
Published: March 2015

AbstractObjectiveThis study aimed to examine the acceptability of programme budgeting and marginal analysis (PBMA) as a tool for priority setting in the Indigenous health sector.MethodsThe study uses a mix of quantitative and qualitative methods. A survey of key decision makers in Indigenous health in Victoria was conducted to assess the acceptability of PBMA as a potential tool for priority setting. Respondents comprised 24 bureaucrats from the Victorian Department of Human Services (DHS) and 26 senior executives from the aboriginal community controlled health sector (ACCHS) in Victoria. The survey instrument included both closed‐ended and open‐ended questions and was administered face‐to‐face by a trained researcher in 2007–2008. Closed‐ended questions were analysed using descriptive statistics, and content analysis was used for the open‐ended ones.ResultsThe PBMA was well received as having the potential to improve priority setting processes in Indigenous health. Sixty‐nine percent of the DHS respondents felt that PBMA was acceptable as a routine decision‐making tool, and nearly 80% of ACCHS respondents thought that PBMA was intuitively appealing and would most probably be an acceptable priority setting approach in their organisations. The challenges of using PBMA were related to resource constraints and data intensity.ConclusionProgramme budgeting and marginal analysis is potentially acceptable within the ACCHS and was perceived as useful in terms of assisting the decision maker to maximise health outcomes, but data systems need to be re‐oriented to address its significant data needs.ImplicationProper guidelines need to be developed to facilitate PBMA application within the Indigenous‐controlled community health sector. Copyright © 2015 John Wiley & Sons, Ltd.
Non‐linear imaging and characterization of atherosclerotic arterial tissue using combined SHG and FLIM microscopy
Authors: Cicchi Riccardo , Baria Enrico , Matthäus Christian , Lange Marta , Lattermann Annika , Brehm Bernhard R. , Popp Jürgen , Pavone Francesco Saverio 
Published: March 2015

Atherosclerosis is one of the leading causes of death in the Western World and its characterization is extremely interesting from the diagnostic point of view. Here, we employed combined SHG‐FLIM microscopy to characterize arterial tissue with atherosclerosis. The shorter mean fluorescence lifetime measured within plaque depositions (1260 ± 80 ps) with respect to normal arterial wall (1480 ± 100 ps) allowed discriminating collagen from lipids. SHG measurements and image analysis demonstrated that the normal arterial wall has a more anisotropic Aspect Ratio (0.37 ± 0.02) with respect to plaque depositions (0.61 ± 0.02) and that the correlation length can be used for discriminating collagen fibre bundles (2.0 ± 0.6 µm) from cholesterol depositions (4.1 ± 0.6 µm). The presented method has the potential to find place in a clinical setting as well as to be applied in vivo in the near future.
Graphic composition of SHG and FLIM images representing normal arterial wall and plaque depositions.magnified imageGraphic composition of SHG and FLIM images representing normal arterial wall and plaque depositions.
High conversion efficiency of Japanese cedar hydrolyzates into acetic acid by co‐culture of Clostridium thermoaceticum and Clostridium thermocellum
Authors: Rabemanolontsoa Harifara , Kuninori Yoshimizu , Saka Shiro 
Published: March 2015

AbstractBACKGROUNDAcetic acid is an important reagent and precursor in chemical and material industries. It is largely manufactured from fossil resources, but with increasing environmental concerns and uncertain petroleum availability, producing organic acids from renewable biomass has become a priority. Several researchers have demonstrated acetic acid production from model compounds, food products or a minor portion of lignocellulosic biomass but the simultaneous fermentation of all biomass‐derived products has not been reported yet. This work demonstrates the unique capabilities of Clostridium thermoaceticum and Clostridium thermocellum in co‐culture to convert most products obtained from hot‐compressed water treatment of Japanese cedar into acetic acid.RESULTSUnder an optimal pH found to be 6.5, most cello‐oligosaccharides and xylo‐oligosaccharides as well as the majority of monosaccharides were completely consumed after 40 h, while the lignin‐derived products, organic acids, decomposed and dehydrated compounds required 72 h to be fermented. Overall, it was found that most of the water‐soluble lignocellulosic hydrolyzates were successfully transformed into acetic acid, leading to a high carbon conversion efficiency of 84.9%.CONCLUSIONBiomass‐derived compounds from hot‐compressed water treatment were efficiently converted to acetic acid, a valuable intermediate for further biotechnological production of chemicals and materials to substitute fossil‐derived ones. © 2015 Society of Chemical Industry
Sol‐gel method to obtain the ferroelectromagnetic ceramics (Pb(Fe0.5Nb0.5)O3) for micromechatronic applications
Authors: Bochenek D. , Zachariasz R. 
Published: March 2015

Lead iron niobate, Pb(Fe0.5Nb0.5)O3 belong to a family of materials with a perovskite structure with the general formula A(B′B″)O3, where in positions A–Pb ions substitute themselves, and in octahedral positions B′ and B″ ions of iron Fe and niobium Nb in a random way. The Pb(Fe0.5Nb0.5)O3 material is characterized by two ordered antiferromagnetic and ferroelectric sub‐systems. A technological process of the ferroelectromagnetic Pb(Fe0.5Nb0.5)O3 ceramics have a significant influence on a crystalline structure and a ceramics microstructure.In the present paper, we study a sol‐gel technology of the production of the Pb(Fe0.5Nb0.5)O3 ceramics. The obtained specimens were subjected to micro‐structural examinations and tests of mechanical and dielectric properties. Temperature dependences of mechanical loss Q–1(T) and Young's modulus E(T) were conducted by an automatic relaxator of acoustic frequencies of a RAK‐3 type and dielectric test were made on a capacity bridge of a QuadTech 1920 Precision LCR Meter type.
Genome‐wide mapping of TnrA‐binding sites provides new insights into the TnrA regulon in Bacillus subtilis
Authors: Mirouze Nicolas , Bidnenko Elena , Noirot Philippe , Auger Sandrine 
Published: March 2015

AbstractUnder nitrogen limitation conditions, Bacillus subtilis induces a sophisticated network of adaptation responses. More precisely, the B. subtilis TnrA regulator represses or activates directly or indirectly the expression of a hundred genes in response to nitrogen availability. The global TnrA regulon have already been identified among which some directly TnrA‐regulated genes have been characterized. However, a genome‐wide mapping of in vivo TnrA‐binding sites was still needed to clearly define the set of genes directly regulated by TnrA. Using chromatin immunoprecipitation coupled with hybridization to DNA tiling arrays (ChIP‐on‐chip), we now provide in vivo evidence that TnrA reproducibly binds to 42 regions on the chromosome. Further analysis with real‐time in vivo transcriptional profiling, combined with results from previous reports, allowed us to define the TnrA primary regulon. We identified 35 promoter regions fulfilling three criteria necessary to be part of this primary regulon: (i) TnrA binding in ChIP‐on‐chip experiments and/or in previous in vitro studies; (ii) the presence of a TnrA box; (iii) TnrA‐dependent expression regulation. In addition, the TnrA primary regulon delimitation allowed us to improve the TnrA box consensus. Finally, our results reveal new interconnections between the nitrogen regulatory network and other cellular processes.
Cerebral perfusion and cortical thickness indicate cortical involvement in mild Parkinson's disease
Authors: Madhyastha Tara M. , Askren Mary K. , Boord Peter , Zhang Jing , Leverenz James B. , Grabowski Thomas J. 
Published: March 2015

AbstractCortical dysfunction in Parkinson's disease (PD) may be caused by disruption to ascending systems or by intrinsic cortical neuropathology. We introduce and conduct a joint analysis of metabolism and atrophy capable of identifying whether metabolic disruption occurs in mild PD without cortical atrophy, to determine the extent and spatial pattern of cortical involvement in mild PD. The design was observational, studying 23 cognitively normal participants with mild PD (mean Hoehn & Yahr stage 2) and 21 healthy controls. Cortical thickness (obtained from analysis of structural magnetic resonance imaging [MRI] with FreeSurfer) and cerebral perfusion measures (obtained from arterial spin labeling [ASL]) analyzed independently and then together in a joint multiple factorial analysis to identify spatial patterns of perfusion and cortical thickness. We identify a pattern of changes in perfusion and cortical thickness characterized by symmetric parietal cortical thinning and reduced precuneus perfusion, with relative preservation of thickness and perfusion in the anterior cingulate cortex (ACC), right prefrontal gyrus, and medial frontal gyrus. The expression of this pattern is correlated with motor system symptoms and speed of processing. A spatial pattern of joint parietal cortical thinning and disproportionate reduction in perfusion occurs in our nondemented PD sample. We found no PD‐related components of reduced perfusion without cortical thinning. This suggests that PD affects the cortex itself, even when symptoms are relatively mild. © 2015 International Parkinson and Movement Disorder Society
Platelet mitochondrial activity and pesticide exposure in early Parkinson's disease
Authors: Bronstein Jeff M. , Paul Kimberly , Yang Laurice , Haas Richard H. , Shults Clifford W. , Le Thuy , Ritz Beate 
Published: March 2015

AbstractBackgroundMitochondrial dysfunction has been implicated in the pathogenesis of Parkinson's disease (PD), but the cause of this dysfunction is unclear.MethodsPlatelet mitochondrial complex I and I/III (nicotinamide adenine dinucleotide cytochrome c reductase, NCCR) activities were measured in early PD patients and matched controls enrolled in a population‐based case‐control study. Ambient agricultural pesticide exposures were assessed with a geographic information system and California Pesticide Use Registry.ResultsIn contrast to some previous reports, we found no differences in complex I and I/III activities in subjects with PD and controls. We did find that NCCR activity correlated with subjects' exposure to pesticides known to inhibit mitochondrial activity regardless of their diagnosis.ConclusionsElectron transport chain (ETC) activity is not altered in PD in this well‐characterized cohort when compared with community‐matched controls but appears to be affected by environmental toxins, such as mitochondria‐inhibiting pesticides. © 2015 International Parkinson and Movement Disorder Society