bluuebunny/crossref_metadata_2025_split huggingface dataset:
Primary Lymphoma of Bone Complicating Total Knee Arthroplasty: An Unexpected Mode of Prosthesis Failure
Authors: Ibrahim Ishaq , Haughom Bryan D. , Fillingham Yale A. , Brown Nicholas , Gitelis Steven 
Published: April 2015

Case:
Primary lymphoma of bone is a rare musculoskeletal malignancy that typically arises in long bones. Few cases of bone lymphoma occurring alongside orthopaedic implants have been reported in the literature. We describe the complex case of a seventy-eight-year-old woman who developed diffuse large B-cell lymphoma of the proximal part of the tibia five years after a successful total knee arthroplasty.

Conclusion:
Several studies have suggested a link between orthopaedic implants and genomic instability, although true carcinogenesis remains questionable. Lymphoma complicating joint arthroplasty poses a unique problem for orthopaedic physicians due to diagnostic challenges and the unique implications of disease and treatment-related complications.
The effect of anodizing conditions on the corrosion resistance of Ti6Al4V titanium alloy
Authors: Łępicka Magdalena , Grądzka-Dahlke Małgorzata , Sobolewski Andrzej 
Published: April 2015

Abstract
To improve the biocompatibility and operational safety of titanium implants made of Ti6Al4V alloy, anodizing is applied. The anodizing process allows adjustment of the highly biocompatible oxide level on the metallic surface. However, little attention is paid to the influence of the layer thickness on the considered material corrosion resistance. Electrochemical polarization and open circuit potential tests as well as scanning electron microscope, laser confocal microscope and energy-dispersive X-ray studies were performed on as-received samples. Taking all experimental investigations into account, the following conclusions can be formulated: 1. Anodizing of Ti6Al4V alloy results in improvement of its corrosive characteristics. 2. In general, the higher the anodizing voltage is, the worse the anticorrosive properties exhibited by the material. 3. Despite the observed corrosion characteristics, the titanium oxide films obtained by means of the anodizing technique can be severely corroded in 0.9 wt.-% NaCl aqueous solution.
Frequency analysis of volumetric porosity in aluminum castings at high and low cooling rates
Authors: Al Mufadi Fahad A. , Irfan Mohammad A. 
Published: April 2015

Abstract
Three dimensional porosity analysis was conducted using computed tomography for Al-Si alloy castings. Statistical analysis was performed to compare the porosities of the castings at high and low cooling rates. It was observed that the cooling rates strongly affect the formation of pores for both small and large pores. The incidence of small pores measuring 0.00003 mm3 to 0.0004 mm3 can be up to six times higher in castings formed at low cooling rates. For large pores measuring 300 μm to 360 μm, it was observed that lower cooling rates give rise to larger pores, which are known to be detrimental to castings as potential failure initiation sites.
Estimation of the mechanical properties of nanocomposites based on the properties prediction of single wall carbon nanotubes (SWCNT)
Authors: Hedia Hassan S. , Aldousari Saad M. , Abdellatif Ahmed K. , Abdelhaffez Gamal S. 
Published: April 2015

Abstract
A finite element model has been developed based on molecular mechanics to predict the mechanical properties of single wall carbon nanotubes (SWCNT). In addition, the mechanical properties of nanocomposite were investigated analytically and experimentally. This work consists of three parts; the first part is prediction of Young's modulus of single wall carbon nanotubes by molecular mechanics based finite element modeling. The second part describes the experimental work. The third part deals with the validation of the analytical part and the experimental work. The mechanical properties of SWCNT were obtained from FE. The mechanical properties of neat epoxy were experimentally determined. Both of them were used to estimate the mechanical properties of SWCNT/epoxy nanocomposite analytically. A comparison between the analytical and experimental results of SWCNT/epoxy nanocomposite has been done. The modeling and analysis of (SWCNT) were carried out using FEM by MATLAB and ANSYS software. However, in the experimental work the epoxy resin was modified by adding SWCNT with different ratio, i. e. 0, 0.1, 0.3, 0.5 and 0.7 wt.-%, respectively. The materials were characterized in tension to obtain the mechanical properties of SWCNT/epoxy nanocomposite experimentally. The results from the FE model were compared with the results in the literature and good agreement was achieved. The FE approach is a valuable tool for studying the mechanical behavior of carbon nanotubes. The results show that a nanotube weight percent of 0.3 wt.-% of SWCNT improves all mechanical properties such as tensile strength, modulus of elasticity and toughness. The weight percent greater than 0.5 wt.-% SWCNT should be avoided. To predict the mechanical properties of the composite materials analytically, it is worth considering the conventional rule of mixtures using the reasonable nanotube volume fractions and exact value of the efficiency parameter.
Effects of Y2O3 and Al2O3 sintering additives on the hot pressing behavior of AlN ceramics
Authors: Lee Sungkyu , Jung Hang Chul , Cho Sung-Su , Hong Hyun Seon 
Published: April 2015

Abstract
AlN plates were fabricated by hot pressing AlN-Y2O3 and AlN-Y2O3-Al2O3 powder mixtures at 1700–1900 °C using yttria and alumina (Al2O3 particle sizes of 3 and 10 μm) powders as sintering additives. The physical and mechanical properties of the hot-pressed AlN ceramics were characterized using X-ray diffraction (XRD), scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDS). The density, thermal conductivity, transverse rupture strength, and grain size were measured. The thermal conductivity of the hot–pressed AlN ceramics ranged between 83–92.7 W × (m × K)−1 and decreased with the addition of Al2O3, whereas the mechanical properties improved with the addition of Al2O3, which is known to have a beneficial effect of grain size refinement. The measured density values of 3.31 to 3.34 g × cm−3 were slightly higher than the theoretical density of 3.26 g × cm−3. This result was attributed to the use of a carbon mold under N2 atmosphere, which effectively removed oxygen atoms from the yttrium-aluminate phase that is expected to form at 1100 °C.
Effect of the powder particle size on the wear behavior of boronized AISI 304 stainless steel
Authors: Günen Ali , Küçük Yılmaz , Er Yusuf , Çay V. Veli , Öge Mecit , Gök M. Sabri 
Published: April 2015

Abstract
In this study, the AISI 304 steel specimens were boronized with nanoboron of the size of 10–50 nm and commercial Ekabor 3 powders (<1400 μm) at 950 °C to 1000 °C for 2 h and 4 h. Boronized steel specimens were characterized via SEM, microhardness and XRD analyses. Abrasive wear behavior of the specimens, boronized at different temperatures and treatment durations, were examined. The fixed ball micro-abrasion tests were carried out using the abrasive slurry, prepared with different SiC powder particle sizes on the boronized specimens at different rotational speeds. The specimens boronized with nanoboron powders exhibited a higher hardness and abrasive wear resistance than the samples boronized with the Ekabor 3 powders.
Effect of plasma nitriding time on surface properties of hard chromium electroplated AISI 1010 steel
Authors: Kocabaş Mustafa , Danışman Murat , Cansever Nurhan , Ülker Şükrü 
Published: April 2015

Abstract
Properties of steel can be enhanced by surface treatments such as coating. In some cases, further treatments such as nitriding can also be used in order to get even better results. In order to investigate the properties of nitride layer on hard Cr coated AISI 1010 steel, substrates were electroplated to form hard Cr coatings. Then hard Cr coatings were plasma nitrided at 700 °C for 3 h, 5 h and 7 h and nitride phases on the coatings were investigated by X-ray diffraction analysis. The layer thickness and surface properties of nitride films were investigated by scanning electron microscopy. The hardness and adhesion properties of Cr-N phases were examined using nano indentation and Daimler-Benz Rockwell C adhesion tests. The highest measured hardness was 24.1 GPa and all the three samples exhibited poor adhesion.
Chapitre 6. L’information sur le médicament
Authors: Foucher Jean-Pierre 
Published: April 2015

Un médicament n’étant pas un produit comme un autre, le prescripteur, le dispensateur et le patient doivent être en possession d’une information relative aux caractéristiques du produit. Cette information doit être complète, objective et scientifiquement rigoureuse. Elle doit s’adapter au besoin et être compréhensible. Elle doit aider à la prescription, faciliter la dispensation et faire adhérer le patient à son traitement. Ainsi, selon le destinataire, cette information sera différente. C’est au pharmacien et au médecin de l’utiliser pour l’éducation thérapeutique du patient. L’information donnée doit être objective. Ce sont les fiches de transparence ainsi que les notices qui accompagne le médicament qui doivent être considérées comme les plus fiables. On peut également trouver des informations dans les grandes revues de publications scientifiques, dans des bulletins indépendants créés par des groupes de médecins et de pharmaciens ou encore dans des guides thérapeutiques. Il faut être très réservé quant aux informations trouvées sur certains sites « Internet ».
La fabrication des rêves, processus individuel et collectif ?
Authors: Schurmans Dan 
Published: April 2015

Quand une personne équilibrée dit qu’elle a fait un rêve prémonitoire, et que dans sa culture ce type de rêves est fréquent, qu’est-ce que cela signifie quant au processus psychique qui a produit le rêve ? Le contexte collectif influence-t-il le contenu et la signification des rêves ? Pour la tradition populaire, il existe une intentionnalité propre au rêve, une tendance à se faire réalité, et cette tendance se renforce du récit qu’on en fait. En outre, le rêveur se trouve, au moment où il rêve, et du fait de son rêve, dans un état de vulnérabilité par rapport aux intentions malveillantes d’autrui. Là aussi, le récit, la mise en mots, aggrave le problème. Je propose d’examiner ces assertions, en mettant entre parenthèses l’idée a priori que nous pourrions en avoir, et ensuite de nous demander s’il existe, entre les théories populaires et les théories psychanalytiques, des relations d’opposition ou de complémentarité. Ce travail, basé sur la clinique avec les migrants, montre que la construction des rêves est polysémique, et que l’interprétation doit être adaptée aux besoins du patient. Il met en évidence que les rêves forment souvent une séquence qui traduit la recherche prospective d’une solution destinale.
La nostalgie : rêve ou cauchemar ?
Authors: Rauchs Paul 
Published: April 2015

Le mot nostalgie vient du vocabulaire médical : de 1688 jusqu’au XIX e siècle il désignait un état dépressif grave menant à la mort et causé par le mal du pays. Cette description ne répond bien sûr plus aux canons de la scientificité contemporaine, mais la nostalgie n’en continue pas moins de teinter le vécu de l’exilé. Le rêve lui-même est en quelque sorte un exil qui peut virer au cauchemar. En partant des rêves collectés par Charlotte Beradt auprès des exilés intérieurs du Troisième Reich, l’auteur s’interroge sur les liens entre l’ancienne acception du concept de nostalgie et les acquis de la psychanalyse.
Le vent qui emporte la vie. Décompensation psychotique chez une femme migrante bambara du Mali atteinte de la maladie du Sida
Authors: Koumentaki Chryssanthi , Idris Isam , Moro Marie Rose 
Published: April 2015

Comment traiter des décompensations psychotiques survenant dans un contexte de maladies somatiques graves comme le Sida chez des adultes migrants adressés à une consultation transculturelle en dernier recours ? Cette question a peu été traitée dans la littérature transculturelle de ces dernières années, c’est pourquoi, à titre exploratoire, nous proposons ici une monographie sur une prise en charge psychothérapique longue chez une femme bambara du Mali. L’analyse de l’histoire clinique sera faite avec une méthodologie complémentariste qui utilise l’anthropologie et la psychanalyse. Nous discuterons ensuite les questions cliniques, contre-transférentielles et thérapeutiques soulevées par cette situation complexe : trauma, psychose et mort.
Fc Engineering of Human IgG1 for Altered Binding to the Neonatal Fc Receptor Affects Fc Effector Functions
Authors: Grevys Algirdas , Bern Malin , Foss Stian , Bratlie Diane Bryant , Moen Anders , Gunnarsen Kristin Støen , Aase Audun , Michaelsen Terje Einar , Sandlie Inger , Andersen Jan Terje 
Published: April 2015

Abstract
Engineering of the constant Fc part of monoclonal human IgG1 (hIgG1) Abs is an approach to improve effector functions and clinical efficacy of next-generation IgG1-based therapeutics. A main focus in such development is tailoring of in vivo half-life and transport properties by engineering the pH-dependent interaction between IgG and the neonatal Fc receptor (FcRn), as FcRn is the main homeostatic regulator of hIgG1 half-life. However, whether such engineering affects binding to other Fc-binding molecules, such as the classical FcγRs and complement factor C1q, has not been studied in detail. These effector molecules bind to IgG1 in the lower hinge–CH2 region, structurally distant from the binding site for FcRn at the CH2–CH3 elbow region. However, alterations of the structural composition of the Fc may have long-distance effects. Indeed, in this study we show that Fc engineering of hIgG1 for altered binding to FcRn also influences binding to both the classical FcγRs and complement factor C1q, which ultimately results in alterations of cellular mechanisms such as Ab-dependent cell-mediated cytotoxicity, Ab-dependent cellular phagocytosis, and Ab-dependent complement-mediated cell lysis. Thus, engineering of the FcRn–IgG1 interaction may greatly influence effector functions, which has implications for the therapeutic efficacy and use of Fc-engineered hIgG1 variants.
Staphylococcus aureus Adenosine Inhibits sPLA2-IIA–Mediated Host Killing in the Airways
Authors: Pernet Erwan , Brunet Jérémy , Guillemot Laurent , Chignard Michel , Touqui Lhousseine , Wu Yongzheng 
Published: April 2015

Abstract
Staphylococcus aureus is a common cause of bacterial infections in respiratory diseases. It secretes molecules to dampen host immunity, and the recently identified adenosine is one of these molecules. The type IIA secretory phospholipase A2 (sPLA2-IIA) is a host protein endowed with antibacterial properties, especially against Gram-positive bacteria such as S. aureus. However, the role of adenosine in sPLA2-IIA–mediated S. aureus killing by host is still unknown. The present studies showed that the S. aureus mutant lacking adenosine production (∆adsA strain) increased sPLA2-IIA expression in guinea pig airways and was cleared more efficiently, compared with the wild-type strain. S. aureus ∆adsA strain induced sPLA2-IIA expression by alveolar macrophages after phagocytic process via NOD2–NF-κB–dependent mechanism. However, S. aureus adenosine (wild-type and adsA-complemented strains) and exogenous adenosine downregulated S. aureus phagocytosis by alveolar macrophages, leading to inhibition of sPLA2-IIA expression. This occurred through inhibition of p38 phosphorylation via adenosine receptors A2a-, A2b-, and protein kinase A–dependent pathways. Taken together, our studies suggest that, in the airway, S. aureus escapes sPLA2-IIA–mediated killing through adenosine-mediated inhibition of phagocytosis and sPLA2-IIA expression.
Platelet-Driven Leukotriene C4–Mediated Airway Inflammation in Mice Is Aspirin-Sensitive and Depends on T Prostanoid Receptors
Authors: Liu Tao , Garofalo Denise , Feng Chunli , Lai Juying , Katz Howard , Laidlaw Tanya M. , Boyce Joshua A. 
Published: April 2015

Abstract
Cysteinyl leukotrienes (cysLTs) are bronchoconstricting lipid mediators that amplify eosinophilic airway inflammation by incompletely understood mechanisms. We recently found that LTC4, the parent cysLT, potently activates platelets in vitro and induces airway eosinophilia in allergen-sensitized and -challenged mice by a platelet- and type 2 cysLT receptor–dependent pathway. We now demonstrate that this pathway requires production of thromboxane A2 and signaling through both hematopoietic and lung tissue–associated T prostanoid (TP) receptors. Intranasal administration of LTC4 to OVA-sensitized C57BL/6 mice markedly increased the numbers of eosinophils in the bronchoalveolar lavage fluid, while simultaneously decreasing the percentages of eosinophils in the blood by a TP receptor–dependent mechanism. LTC4 upregulated the expressions of ICAM-1 and VCAM-1 in an aspirin-sensitive and TP receptor–dependent manner. Both hematopoietic and nonhematopoietic TP receptors were essential for LTC4 to induce eosinophil recruitment. Thus, the autocrine and paracrine functions of thromboxane A2 act downstream of LTC4/type 2 cysLT receptor signaling on platelets to markedly amplify eosinophil recruitment through pulmonary vascular adhesion pathways. The findings suggest applications for TP receptor antagonists in cases of asthma with high levels of cysLT production.
A Humanized Monoclonal Antibody against Heat Shock Protein 60 Suppresses Murine Arthritis and Colitis and Skews the Cytokine Balance toward an Anti-Inflammatory Response
Authors: Ulmansky Rina , Landstein Dorit , Moallem Eli , Loeb Virginie , Levin Avi , Meyuhas Ronit , Katzavian Galia , Yair Shira , Naparstek Yaakov 
Published: April 2015

Abstract
We have previously shown that naturally occurring as well as acquired Abs against the Mycobacterium tuberculosis heat shock protein (HSP)65 protect against the induction of murine autoimmune inflammatory arthritis. In the present work, we have studied the anti-inflammatory effect of prozumab, a humanized anti-HSP mAb in murine inflammatory arthritis and colitis, and its effects on cytokine secretion. Prozumab was shown to bind to HSP60, the highly conserved mammalian homolog of the bacterial protein, and it was found to be effective in protecting and suppressing autoimmune arthritis in the models of adjuvant arthritis and collagen-induced arthritis in rats and mice, respectively, as well as in acute hapten-mediated colitis and chronic, spontaneous colitis models. Mechanistically, prozumab induces IL-10 secretion from naive human PBMCs and suppresses the secretion of IFN-γ and IL-6 from anti-CD3–activated human PBMCs. These findings make prozumab a promising potential drug for treating human rheumatoid arthritis and inflammatory bowel disease, as well as a wide range of autoimmune inflammatory diseases.
On Positive Definiteness Over Locally Compact Quantum Groups
Authors: Runde Volker , Viselter Ami 
Published: April 2015

AbstractThe notion of positive-definite functions over locally compact quantum groups was recently introduced and studied by Daws and Salmi. Based on this work, we generalize various well-known results about positive-definite functions over groups to the quantum framework. Among these are theorems on “square roots” of positive-definite functions, comparison of various topologies, positive-definite measures and characterizations of amenability, and the separation property with respect to compact quantum subgroups.
Katherine Mansfield, Rhythm, and Metropolitan Primitivism
Authors: Snyder Carey 
Published: April 2015

ABSTRACT
Recent scholarship has enriched our understanding of the role that Rhythm played in the emergence of early modernism, but the magazine's pronounced primitivism has gone largely unremarked. This article argues that, as co-editor and contributor, Katherine Mansfield negotiated an ambivalent relationship to the magazine's primitivism—ranging from romantic idealization of indigenous people to satirical mockery of the western European fascination with exotic cultures and artifacts that pervades Rhythm's pages. It shows that while Mansfield's Rhythm writings largely frustrate metropolitan desires for quaint exoticism, the writer did not fully escape the dynamics she ridiculed.
Photoplay, Literary Celebrity, and The Little Review
Authors: Hannah Matthew 
Published: April 2015

ABSTRACT
Under the editorship of Margaret Anderson, Jane Heap, and Ezra Pound, The Little Review published many of the most celebrated modernists during its fifteen-year run. The magazine included extensive letter columns that invited readers to insinuate themselves as “critics” into aesthetic discussions. Anderson published these letters alongside letters from rising modernist artists. I read this layering alongside celebrity culture in fan clubs and film magazines that created an atmosphere of access and perpetuated desires for contact. Similarly, Anderson used the burgeoning celebrity of modernists as a draw for readers. Combining this deployment of literary celebrity with promotional contests and reading groups, Anderson marketed the magazine for aspirant-intellectuals, mirroring access narratives in film-fan magazines of the period.
Interferences of Surfactants During Determination of Chlorophenols by Acetylation Coupled to Headspace-Solid Phase Microextraction-Gas Chromatography with an Electron Capture Detector
Authors: Stoichev Teodor , de Morais Paulo , Basto M Clara P , Vasconcelos M Teresa S D 
Published: April 2015

Abstract
The micellar extraction (ME) of chlorophenols (CPs) from solid samples is rapid and avoids the use of organic solvents. The cationic surfactant cetyltrimethylammonium bromide (CTAB) is a powerful agent for ME of CPs. However, CTAB will be an important interference when the extracts are subsequently analyzed by direct solid phase microextraction (SPME) without a previous derivatization step. Therefore, CTAB is usually replaced by the nonionic surfactant polyoxyethylene-10-lauryl ether (POLE), which causes less interference but is less efficient in extracting CPs. In order to assess to what extent the derivatization of CPs with headspace (HS) sampling would be able to reduce surfactant interferences, CPs were measured in the presence of CTAB or POLE using acetylation and HS-SPME coupled to GC with an electron capture detector. Experiments were carried out both in water and in a 0.1 g/mL solution of NaCl (salting out agent). Acetylation and HS-SPME strongly decreased the interference of CTAB for CP determination. Therefore, the application of CTAB followed by SPME determination for an efficient ME of CPs from solid samples should be reconsidered since using CTAB with HS-SPME after acetylation proved to be a potential tool for CP determination in those matrixes after method optimization.
Development and Validation of a High Performance Liquid Chromatographic Method for Simultaneous Determination of Vitamins A and D3 in Fluid Milk Products
Authors: Chen Yang , Reddy Ravinder M , Li Wenjing , Yettlla Ramesh R , Lopez Salvador , Woodman Michael 
Published: April 2015

Abstract
An HPLC method for simultaneous determination of vitamins A and D3 in fluid milk was developed and validated. Saponification and extraction conditions were studied for optimum recovery and simplicity. An RP HPLC system equipped with a C18 column and diode array detector was used for quantitation. The method was subjected to a single-laboratory validation using skim, 2% fat, and whole milksamples at concentrations of 50, 100, and 200% of the recommended fortification levels for vitamins A and D3 for Grade “A” fluid milk. The method quantitation limits for vitamins A and D3 were 0.0072 and 0.0026 μg/mL,respectively. Average recoveries between 94 and 110%and SD values ranging from 2.7 to 6.9% were obtainedfor both vitamins A and D3. The accuracy of the method was evaluated using a National Institute of Standards and Technology standard reference material (1849a) and proficiency test samples.