bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of Hydrothermal Parameters on the Synthesis of Nanocrystalline Zeolite NaY
Authors: Nouri Amir , Jafari Mostafa , Kazemimoghadam Mansour , Mohammadi Toraj 
Published: February 2013

AbstractSynthesized zeolites are extremely important as industrial minerals and are most commonly prepared using organic templates. Because these organic templates present undesirable environmental hazards, a synthesis method which avoids their use is desirable. The objective of the current study was to develop such a synthesis method. Zeolite NaY was synthesized hydrothermally starting from a mixture of 1.0 Al2O3:10 SiO2:4.6 Na2O:180 H2O molar gel composition, without adding any organic additives. Experiments were carried out to investigate the effects of molar compositions including water content (H2O/SiO2), crystallization conditions including temperature, and time on the crystal size and yield of NaY-type zeolite. The results showed that increasing the crystallization time from 5 to 12 h increased the crystal size, while increasing the crystallization temperature from 80 to 100°C also increased crystallinity. The crystal species of zeolite NaY were characterized by X-ray diffraction, X-ray fluorescence, and scanning electron microscopy analysis. Zeolite NaY crystals in the size range 25–150 nm were synthesized successfully over a period of 8 h at 100°C.
PUBLICATION REVIEWS
Authors: Maier Danica , Olding Simon 
Published: February 2013

Anne Wilson: Wind/Rewind/Weave, Anne Wilson (2011) Chicago: University of Chicago Press, 159 pp, ISBN: 978-0-945-32322-8, p/bk, $30.00/£19.50
Stephen De Staebler: Matter and Spirit, Timothy Anglin Burgard (2012) San Francisco: The Fine Arts Museum of San Francisco in
association with University of California Press, 240 pp, ISBN: 978-0-520-27230-9, p/bk, $34.95
Reviews
Authors: Sterritt David , Yates Steven , Conterio Martyn , Abecassis Michaël , Collis Leo 
Published: February 2013

Cinema Italiano: The Complete Guide from Classics to Cult, Howard Hughes, (2011)London: I.B. Tauris & Co Ltd, 311pp., ISBN: 9781848856080 (pbk), £14.99
The Cinema of Mika Kaurismäki: Transvergent Cinescapes, Emergent Identities, Pietari Kääpä, (2011)
Bristol: Intellect, 208pp., ISBN: 9781841504094 (pbk), $50
African Chelsea (2011) USA Director Brent Roske Written by Brent Roske With Corrinne Becker (Chelsea), Tosa Oghbagado (Tosa – Bouncer), Jilon VanOver (Jack) and Sally Kirkland (Anna)Runtime 6 minutes Produced and Distributed
by Roske Entertainment LTD
Around the Circuit
Authors: Grant Barry Keith , Prout Ryan , Radomski Marcin 
Published: February 2013

Toronto International Film Festival 2012: 6-12 September, 2012 A report by Barry Keith Grant
Madeira FilmFestival 2012: 2-6 May, 2012 A Report by Ryan Prout
Expand New Horizons in Poland T-Mobile New Horizons International Film Festival: 19 - 29 July 2012 A report by Marcin Radomski
REVIEWS
Authors: Turner Annie , Griffiths Sue , xSeton Dr Mark 
Published: February 2013

DEVELOPING A NARRATIVE APPROACH TO HEALTHCARE RESEARCH, VIV MARTIN (2010) Oxford: Radcliffe Publishing, 198pp., ISBN: 9781846194009, p/bk, £24.99
AN INQUIRY INTO MAKING SENSE OF OUR LIVES, WARREN LETT (2011) Eltham, Australia: Rebus Press, 288 pp., ISBN: 978-0646558752, p/bk,
AUS$50.00
LIVING WITH A CREATIVE MIND, JEFF CRABTREE AND JULIE CRABTREE (2011) Australia: Zebra Collective, 325 pp., ISBN: 9780987104601, p/bk AUS$29.95 (e-book AUS$19.95)
BOOK REVIEWS
Authors: Starks Michael , Rashid Imir 
Published: February 2013

DIGITAL UNIVERSE: THE GLOBAL TELECOMMUNICATION REVOLUTION, PETER B. SEEL (2012) Chichester: Wiley-Blackwell, 276 pp., ISBN: 978-1-4051-5330-0, p/bk, £21.99 (also available in h/bk)
HIGH-DEFINITION TELEVISION: THE CREATION, DEVELOPMENT AND IMPLEMENTATION OF HDTV TECHNOLOGY,
PHILIP J. CIANCI (2012) JEFFERSON, NORTH CAROLINA AND LONDON: MCFARLAND & COMPANY INC. PUBLISHERS, 373 PP., ISBN: 978-0-7864-4975-0, P/BK, £36.58 ($45.00)
REVIEWS
Authors: Lundskaer-Nielsen Miranda , Radcliffe Caroline , Pamela Karantonis 
Published: February 2013

MICHENER’S SOUTH PACIFIC, STEPHEN J. MAY (2011) Gainesville: University Press of Florida, 176 pp., ISBN: 978-0-8130-3557-4, h/bk, $24.95
SOUTH PACIFIC: PARADISE REWRITTEN, JIM LOVENSHEI MER (2010) New York: Oxford University Press, 266 pp., ISBN: 978-0-19-537702-6, h/bk,
$27.95
MELODRAMATIC VOICES: UNDERSTANDING MUSIC DRAMA, SARAH HIBBERD (ED.) (2012) Surrey: Ashgate Publishing Limited, 314 pp., ISBN: 978-1-4094-0082-0, h/bk, £.60.00
ACOUSTIC INTERCULTURALISM– LISTENING TO PERFORMANCE, MARCUSCHENG CHYE TAN (2012) Basingstoke: Palgrave
Macmillan, 259 pp., ISBN 978-0-230-35416-6, h/bk, £50.00
Identification of Candida albicans heat shock proteins and Candida glabrata and Candida krusei enolases involved in the response to oxidative stress
Authors: Cuéllar-Cruz Mayra , Gutiérrez-Sánchez Gerardo , López-Romero Everardo , Ruiz-Baca Estela , Villagómez-Castro Julio , Rodríguez-Sifuentes Lucio 
Published: February 2013

AbstractIn the past two decades, Candida species have become the second leading cause of invasive mycosis in immunocompromised patients. In order to colonize their hosts, these microorganisms express adhesins and cell wall proteins that allow them to adhere and neutralize the reactive oxygen species produced by phagocytic cells during the respiratory burst. However, the precise mechanism by which Candida cell wall proteins change their expression in response to oxidative stress has not been described. In an attempt to understand this change in response to oxidative stress, in this study, three Candida species, namely, C. albicans, C. glabrata and C. krusei, were exposed to increasing concentrations of H2O2 and induced cell wall proteins were identified by two-dimensional gel electrophoresis and peptide mass fingerprinting. Sequence analysis of differential proteins led to the identification of two heat-shock proteins in C. albicans, two enolases in C. glabrata and one enolase in C. krusei. Enolases may be involved in the protection of pathogenic cells against oxidative stress as suggested by the decrease in their expression when they were exposed to high concentrations of H2O2. To our knowledge, this is the first demonstration that expression of these proteins changes in response to oxidative stress in different Candida species. This knowledge can eventually facilitate both an early diagnosis and a more efficient treatment of this mycosis.
Differences in histological and physiological traits of ozone sensitive and resistant bean strains
Authors: Villányi Vanda , Déri Helga , Péli Evelin , Csintalan Zsolt 
Published: February 2013

AbstractAn examination of possible histological causes of differences in ozone sensitivity between ozone sensitive (R123) and resistant (S156) Phaseolus vulgaris strains was carried out. A distinction between the causes and effects of ozone sensitivity was also performed. We studied several morphological and histological traits, which included stomata number and size and also looked at different cell characteristics, such as stomatal index; leaf tissue thickness, fraction and gaseous conductance of intercellular air spaces. Together with this, we made gas-exchange measurements and found inner CO2 levels to be higher in the ozone sensitive strain. We also found several quantitative morphological parameters between the two strains to be initially different, however, these differences changed after exposure to summer climate and ozone. Stomatal function between the two strains was also differently altered by the pollutant, which was apparent from differences in stomatal openness when investigated in summer. According to our histological data, epidermal cells of the ozone sensitive strain grew larger on leaves that developed after exposure to cumulative considerable phytotoxic ozone doses; moderately decreasing the number of stomata and epidermal cells per mm2 epidermal area despite the originally higher number of epidermal cells in sensitive plants. Cross sections of injured sensitive leaves revealed disorganisation of mesophyllum tissues.
Enhancement of docetaxel-treated MCF-7 cell death by 900-MHz radiation
Authors: Trebuňová Marianna , Laputková Galina , Géci Imrich , Andrašina Igor , Sabo Ján 
Published: February 2013

AbstractThe aim of the study was to investigate the effect of high-frequency electromagnetic field of 900 MHz at 8 W input power on metabolic activity of human breast adenocarcinoma MCF-7 cells. With the aid of the colorimetric MTT assay, it was shown that there is significant change in cell culture survival exposed to docetaxel in field-free conditions in comparison with cells treated with docetaxel simultaneously exposed to high-frequency electromagnetic field.
Phylogenetic relations of the dinoflagellate Gymnodinium baicalense from Lake Baikal
Authors: Annenkova Natalia 
Published: February 2013

AbstractFreshwater dinoflagellates still remain poorly studied by modern biological methods. This lack of knowledge prevents us from understanding the evolution and colonization patterns of these ecologically important protists. Gymnodinium baicalense is the most abundant, and possibly endemic, planktonic dinoflagellate from the ancient Lake Baikal. This dinoflagellate species blooms in the spring under the ice. This study analyzed the origin of this Baikalian dinoflagellate using three markers (two ribosomal and one mitochondrial DNA). It was found that this species is a true member of the order Gymnodiniales and has close relatives in the glacial melt waters of the Arctic Ocean. It seems that G. baicalense has diversified relatively recently from the arctic marine gymnodinioids. These results shed light on dinoflagellate biogeography and their colonizations in Lake Baikala biodiversity hotspot.
The Effect of Sinus Surgery with Intensive follow-up on Pathogenic Sinus Bacteria in Patients with Cystic Fibrosis
Authors: Aanaes Kasper , von Buchwald Christian , Hjuler Thomas , Skov Marianne , Alanin Mikkel , Johansen Helle Krogh 
Published: February 2013

Background Most patients with cystic fibrosis (CF) have chronic rhinosinusitis; their sinuses are often colonized with bacteria that can initiate and maintain deleterious pulmonary infections. Theoretically, eradication of the sinus bacteria should reduce the frequency of lung infections and thereby reduce pulmonary morbidity. This article addressed whether bacteria in CF sinuses are eligible for eradication by sinus surgery and postoperative treatment. Methods A prospective study including 58 CF patients, who had extensive sinus surgery and growth of Pseudomonas aeruginosa, Achromobacter xylosoxidans, and/or Burkholderia multivorans in their sinuses, was initiated. All patients followed a systematic postoperative treatment program of nasal irrigations with saline and colistimethate sodium and systematic endoscopic cleansing. All patients had follow-up examinations including sinus cultures; each side of the nose was cultured separately. Results At the 6-month follow-up visit, 49 patients were cultured; 66 of 98 maxillary–ethmoidal complexes (67%) showed no growth of pathogenic bacteria. Some patients were not free from CF pathogenic bacteria at all cultures; however, 20 (41%) patients had no bilateral regrowth (p < 0.01) and 4 patients had no unilateral regrowth at any time during 6 months of follow-up. The eradication of CF pathogens was accomplished in patients from all three lung infection groups: intermittently colonized, chronically infected, and lung transplanted. The patient with the longest follow-up had no bacterial growth for 3 years. Conclusion Extensive sinus surgery combined with intensive follow-up can eradicate pathogenic bacteria from CF sinuses.
Effect of Onchocerca Volvulus Chitinase on MUC5B Expression in Human Airway Epithelial Cells
Authors: Song Si-Youn , Seo Young Jung , Kim Yong-Woon , Park So-Young , Bae Chang Hoon , Kim Yong-Dae 
Published: February 2013

Background Chitin is an essential structural component of the wall of fungal cells and is present in the exoskeleton of arthropods. It has been generally assumed that mammals lack the ability to produce chitinase proteins, the enzymes responsible for chitin degradation. However, recent studies have indicated that mammals produce chitinases and chitinase-like proteins, and chitinase plays a potential role in human asthma and allergic inflammation. In this study, the effect and brief signaling pathway of chitinase on MUC5B expression were investigated in human airway epithelial cells. Methods In the mucin-producing human NCI-H292 airway epithelial cells and the primary cultures of normal nasal epithelial cells, the effect and signaling pathway of chitinase on MUC5B expression were investigated using the reverse transcriptase–polymerase chain reaction (RT-PCR), real-time PCR, enzyme immunoassay, and immunoblot analysis with several specific inhibitors and small interfering RNA (siRNA). Results In the mucin-producing human NCI-H292 airway epithelial cells, chitinase increased MUC5B expression. Chitinase significantly activated the phosphorylation of p38 mitogen-activated protein kinase (MAPK) but not the phosphorylation of extracellular signa-l-related kinase (ERK) 1/2. The SB203580 (p38 MAPK inhibitor) significantly attenuated chitinase-induced MUC5B mRNA expression, but U0126 (ERK1/2 inhibitor) did not. Knockdown of p38 MAPK by p38 MAPK siRNA significantly blocked chitinase-induced MUC5B expression. In the primary cultures of normal nasal epithelial cells, chitinase significantly increased MUC5B gene expression and this was significantly attenuated after pretreatment with SB203580. Conclusion These results suggest that chitinase induces MUC5B expression by activation of the p38 MAPK signaling pathway in human airway epithelial cells.
Antibody Deficiency in Chronic Rhinosinusitis: Epidemiology and Burden of Illness
Authors: Ocampo Christopher J. , Peters Anju T. 
Published: February 2013

Background A subset of patients with chronic rhinosinusitis (CRS) has refractory disease. The risk factors for refractory CRS include atopy, a disrupted mucociliary transport system, medical conditions affecting the sinonasal tract mucosa, and immunodeficiency. Methods We review four primary immunodeficiencies reported in individuals with CRS: common variable immune deficiency (CVID), selective IgA deficiency, IgG subclass deficiency, and specific antibody deficiency. We also review treatment options for individuals with both CRS and a concomitant immune defect. Results There is a high prevalence of CRS in individuals with CVID and selective IgA deficiency. While many reports describe IgG subclass deficiency in individuals with CRS, the clinical relevance of this is unclear. Specific antibody deficiency may play a more significant role in the pathogenesis of refractory CRS. Conclusion Screening for a primary immunodeficiency should be part of the diagnostic workup of refractory CRS, as its identification may allow for more effective long-term therapeutic options.
Nasalance Change after Sinonasal Surgery: Analysis of Voice after Septoturbinoplasty and Endoscopic Sinus Surgery
Authors: Kim Young Ha , Lee Sang Hee , Park Chang Woo , Cho Jin Hee 
Published: February 2013

Background Changes in nasalance caused by resonance change after endonasal surgeries have been reported in prior studies. In clinical practice, although patients often complain of a nasal voice just after surgery, their voices recover over time. The objective of this study was to evaluate the long-term nasalance changes before and after endonasal surgery. Methods Patients who underwent sinonasal surgery at Yeouido St. Mary's Hospital between March 2009 and July 2011 were included in this study. We classified the subjects into three groups according to the surgeries they underwent: group 1, the septoturbinoplasty group; group 2, the endoscopic sinus surgery group; and group 3, the septoturbinoplasty and endoscopic sinus surgery group. We checked acoustic profiles, Grade, Roughness, Breathiness, Asthenia, Strain (GRBAS) scores, and nasalance using a nasometer before and after the sinonasal surgery. Results When considering multidimensional voice program results, no observed parameters showed statistically meaningful changes before or after the operation in all three groups. GRBAS scales in all patients changed less than two scales postoperatively. Nasalance increased at 1 month after the operation in all groups. However, it returned to original levels with time: 3 months in group 2 and 6 months in groups 1 and 3. Conclusion Sinonasal surgery can change the acoustic characteristics of the vocal tract and produce a significant increase in nasality in the early phase. However, after proper healing of the nasal cavity, nasality was observed to become similar to the preoperative level. Therefore, patients, especially voice professionals, do not need to be wary of voice changes after sinonasal surgery.
Effect of Intranasal Fluticasone Furoate and Intraocular Olopatadine on Nasal and Ocular Allergen-Induced Symptoms
Authors: Baroody Fuad M. , Logothetis Hercules , Vishwanath Shilpa , Bashir Mohamad , deTineo Marcella , Naclerio Robert M. 
Published: February 2013

Background Nasal allergen challenge (NAC) leads to a nasal ocular reflex, which is augmented by allergic inflammation. This study was designed to confirm our previous observation that an intranasal steroid inhibits the nasal ocular reflex and to show that histamine does not play an important role in the genesis of this reflex. Methods We performed a randomized, double-blind, double-dummy, placebo (PL)-controlled, four-way crossover trial in subjects with seasonal allergic rhinitis out of season. Subjects were randomized to receive 1 week pretreatment with intranasal PL and intraocular (PL/PL), intranasal PL and intraocular olopatadine (PL/OLO), intranasal fluticasone furoate (FF) and intraocular PL (FF/PL), and the combination (FF/OLO). Subjects then underwent NAC on 2 consecutive days. The number of sneezes and nasal and ocular symptoms were recorded, and levels of tryptase and histamine were measured in nasal lavages. Results NAC after PL/PL resulted in increase in symptoms, histamine, and tryptase after the challenge on the 2nd day. There was a reduction in eye symptoms on the 2nd day of challenge from 6.0 after PL/PL to 0 after FF/PL (p = 0.001), 2.5 after PL/OLO (p = 0.3), and 1.5 after FF/OLO (p = 0.003). Furthermore, there was no significant difference between the response after FF/PL versus FF/OLO and a significant difference between FF/PL and PL/OLO (p = 0.02). Levels of tryptase followed a similar trend. The number of eosinophils in nasal lavages on the 2nd day of challenge were also reduced by the treatment arms containing FF compared with PL. Conclusion Our data confirm the existence of a nasal ocular reflex after NAC. OLO alone or the addition of OLO to FF does not impact ocular symptoms caused by the naso-ocular reflex, suggesting that mast cells are not activated to release histamine in the conjunctiva during this process.
The Impact of Unilateral Concha Bullosa on Mucociliary Activity: An Assessment by Rhinoscintigraphy
Authors: Özkırış Mahmut , Karaçavuş Seyhan , Kapusuz Zeliha , Saydam Levent 
Published: February 2013

Background In this study, we aimed to compare the differences of nasal mucociliary clearance rate (NMCR) by rhinoscintigraphic examination between the nasal cavities of patients with unilateral concha bullosa (CB). Methods The study group consisted of 43 patients (18 men and 25 women), with unilateral CB ranging in age from 20 to 58 years (mean age, 33.5 ± 9.51 years). The nasal mucociliary clearance was described as the velocity (mm/min) of nasal mucociliary transport of the technetium 99m-macroaggragated albumin droplet. Rhinoscintigraphy was performed on each nasal cavity with 2-day intervals in the patients. The mucociliary clearance rates obtained in the unaffected side were accepted as control values. Results The average values for mucociliary clearance rate were 2.29 ± 0.42 mm/min in the CB side of the nasal cavity, and 3.19 ± 0.52 mm/min in the other side of the nasal cavity. Mucociliary transport took a longer time in the CB side of the nasal cavity than in the other side of the nasal cavity, which was found to be statistically significant (p < 0.001). Conclusion Our study showed that unilateral CB might impair NMCR in the ipsilateral side of the nasal cavity. Thus surgical intervention to reduce the middle concha volume may result in a better mucociliary clearance with possibly a less chance of development of chronic sinus diseases and nasal pathologies. Obviously, it is of utmost importance that new studies be planned with larger patient series to better understand nasal mucociliary transport mechanism and CB relationships.
Methotrexate Induces Apoptosis in Nasal Polyps via Caspase Cascades and Both Mitochondria-Mediated and p38 Mitogen-Activated Protein Kinases/Jun N-terminal Kinase Pathways
Authors: Cho Hong Wook , Park Seong Kook , Heo Kyung Wook , Hur Dae Young 
Published: February 2013

Background Methotrexate (MTX) is a very effective treatment for chronic inflammatory diseases that induces apoptosis in nasal polyps (NPs). However, the precise apoptotic pathway in NPs remains unclear. The aim of this study was to identify the apoptotic signaling pathways activated by MTX in NPs. Methods NP tissues were organ cultured using an air–liquid interface method. Cultures were maintained in the presence or absence of MTX (10 or 100 μM) for 24 hours. To investigate apoptotic signaling in NPs, we performed reverse transcription–polymerase chain reaction and Western blotting. Results MTX-treated NPs contained significantly increased amounts of the active forms of caspase 8, caspase 9, and caspase 3 and displayed increased cleavage of poly(ADP-ribose) polymerase. Expression of the proapoptotic molecules Bax and Bad at the mRNA and protein levels and of the activated molecules p-Bad and tBid was significantly higher in MTX-treated NPs than in nontreated NPs. In contrast, expression of the antiapoptotic molecule Bcl-2 at the mRNA and protein levels was significantly lower in MTX-treated NPs than in nontreated NPs. Expression of the phosphorylated forms of p38 mitogen-activated protein kinase (MAPK) and c-Jun N-terminal kinase (JNK) was significantly higher in MTX-treated NPs than in nontreated NPs. In contrast, expression of the phosphorylated form of Akt was significantly lower in MTX-treated NPs than in nontreated NPs. Conclusion MTX induces apoptosis in NPs via caspase cascades and both mitochondria-mediated and p38 MAPK/JNK pathways. We suggest that MTX can be used to treat NPs.