bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Comparison of the Medium-term Impact and Recovery of the Pakistan Floods and the Haiti Earthquake: Objective and Subjective Measures
Authors: Weiss William M. , Kirsch Thomas D. , Doocy Shannon , Perrin Paul 
Published: May 2014

AbstractIntroductionThe 2010 Haiti earthquake and Pakistan floods were similar in their massive human impact. Although the specific events were very different, the humanitarian response to disasters is supposed to achieve the same ends. This paper contrasts the disaster effects and aims to contrast the medium-term response.MethodsIn January 2011, similarly structured population-based surveys were carried out in the most affected areas using stratified cluster designs (80×20 in Pakistan and 60×20 in Haiti) with probability proportional to size sampling.ResultsDisplacement persisted in Haiti and Pakistan at 53% and 39% of households, respectively. In Pakistan, 95% of households reported damage to their homes and loss of income or livelihoods, and in Haiti, the rates were 93% and 85%, respectively. Frequency of displacement, and income or livelihood loss, were significantly higher in Pakistan, whereas disaster-related deaths or injuries were significantly more prevalent in Haiti.ConclusionGiven the rise in disaster frequency and costs, and the volatility of humanitarian funding streams as a result of the recent global financial crisis, it is increasingly important to measure the impact of humanitarian response against the goal of a return to normalcy.WeissWM, KirschTD, DoocyS, PerrinP. A comparison of the medium-term impact and recovery of the Pakistan floods and the Haiti earthquake: objective and subjective measures. Prehosp Disaster Med. 2014;29(3):1-8.
Investigation of the Component Processes Involved in Verbal Declarative Memory Function in Bipolar Disorder: Utility of the Hopkins Verbal Learning Test-Revised
Authors: Van Rheenen Tamsyn E. , Rossell Susan L. 
Published: May 2014

AbstractEvidence suggests that standard learning and recall indexes are sensitive markers of verbal declarative memory ability in bipolar disorder (BD), but no study has examined performance across the full range of component process measures on the Hopkins Verbal Learning Test (HVLT-R) in a BD cohort. As the HVLT-R is part of a widely used battery of cognitive functioning backed by the U.S. Federal Drug Administration as the accepted battery for use in pro-cognitive trials assessing cognitive-enhancing drugs in the related disorder schizophrenia, estimating the utility of its measures in BD is important. Forty-nine BD patients and 51 healthy controls completed the HVLT-R, which was scored for 13 variables of interest, across 4 indices: recall and learning, recognition, strategic organization, and errors. BD patients had greater difficulty in learning the HVLT-R word list compared to controls. They also demonstrated impairment in delayed recall/recognition. There were no differences between the groups in terms of their slope of learning, retrieval index, retention percentage, semantic or serial clustering, errors, or level of retrieval. This pattern was consistent across symptomatic and euthymic patients. The HVLT-R has some utility in characterizing the component processes involved in memory function in BD, such that memory impairments appear to be attributable to deficient encoding processes during the acquisition phase of learning. In the case of planning pro-cognitive clinical trials, the encoding deficits in BD observed here may be sensitive enough to potentially respond to medications designed to enhance the verbal memory performance. (JINS, 2014, 20, 1–9)
Kant and the Art of Schematism
Authors: Matherne Samantha 
Published: May 2014

AbstractIn theCritique of Pure Reason, Kant describes schematism as a ‘hidden art in the depths of the human soul’ (A141/B180–1). While most commentators treat this as Kant's metaphorical way of saying schematism is something too obscure to explain, I argue that we should follow up Kant's clue and treat schematism literally asKunst. By letting our interpretation of schematism be guided by Kant's theoretically exact ways of using the termKunstin theCritique of Judgmentwe gain valuable insight into the nature of schematism, as well as its connection to Kant's concerns in the thirdCritique.
Patriotism, Peace and Poverty: Reply to Bernstein and Varden
Authors: Kleingeld Pauline 
Published: May 2014

AbstractIn this essay I reply to Alyssa Bernstein and Helga Varden's comments on my book, Kant and Cosmopolitanism. In response to Bernstein, I argue that Kant's opposition to the coercive incorporation of states into an international federation should be interpreted as permitting no exceptions. In response to Varden, I clarify Kant's conception and defence of patriotism as a duty, and I show how Kantian cosmopolitans can rebut Bernard Williams's ‘one-thought-too-many’ objection. I also explicate why, given a specific feature of Kant's defence of the state's duty to provide poverty relief, an international federation can be seen to have an analogous duty.
Imatinib mesylate stimulates low-density lipoprotein receptor-related protein 1-mediated ERK phosphorylation in insulin-producing cells
Authors: Fred Rikard G. , Boddeti Santosh Kumar , Lundberg Marcus , Welsh Nils 
Published: May 2014

Low-density lipoprotein receptor-related protein 1 (LRP1) is an endocytic and multi-functional type I cell surface membrane protein, which is known to be phosphorylated by the activated platelet-derived growth factor receptor (PDGFR). The tyrosine kinase inhibitor imatinib, which inhibits PDGFR and c-Abl, and which has previously been reported to counteract β-cell death and diabetes, has been suggested to reduce atherosclerosis by inhibiting PDGFR-induced LRP1 phosphorylation. The aim of the present study was to study LRP1 function in β-cells and to what extent imatinib modulates LRP1 activity. LRP1 and c-Abl gene knockdown was performed by RNAi using rat INS-1 832/13 and human EndoC1-βH1 cells. LRP1 was also antagonized by treatment with the antagonist low-density lipoprotein receptor-related protein associated protein 1 (LRPAP1). We have used PDGF-BB, a PDGFR agonist, and apolipoprotein E (ApoE), an LRP1 agonist, to stimulate the activities of PDGFR and LRP1 respectively. Knockdown or inhibition of LRP1 resulted in increased hydrogen peroxide (H2O2)- or cytokine-induced cell death, and glucose-induced insulin release was lowered in LRP1-silenced cells. These results indicate that LRP1 function is necessary for β-cell function and that LRP1 is adversely affected by challenges to β-cell health. PDGF-BB, or the combination of PDGF-BB+ApoE, induced phosphorylation of extracellular-signal-regulated kinase (ERK), Akt and LRP1. LRP1 silencing blocked this event. Imatinib blocked phosphorylation of LRP1 by PDGFR activation but induced phosphorylation of ERK. LRP1 silencing blocked imatinib-induced phosphorylation of ERK. Sunitinib also blocked LRP1 phosphorylation in response to PDGF-BB and induced phosphorylation of ERK, but this latter event was not affected by LRP1 knockdown. siRNA-mediated knockdown of the imatinib target c-Abl resulted in an increased ERK phosphorylation at basal conditions, with no further increase in response to imatinib. Imatinib-induced cell survival of tunicamycin-treated cells was partially mediated by ERK activation. We have concluded that imatinib promotes LRP1-dependent ERK activation, possibly via inhibition of c-Abl, and that this could contribute to the pro-survival effects of imatinib on β-cells.
A theoretical and experimental study of pressure broadening of the oxygen A-band by helium
Authors: Grimminck Dennis L. A. G. , Spiering Frans R. , Janssen Liesbeth M. C. , van der Avoird Ad , van der Zande Wim J. , Groenenboom Gerrit C. 
Published: May 2014

The rotationally resolved magnetic dipole absorption spectrum of the oxygen A-band \documentclass[12pt]{minimal}\begin{document}$b{^1\Sigma _g^+}\mathrm{(v\!=\!0)}\break \leftarrow \!X{^3\Sigma _g^-}\mathrm{(v\!=\!0)}$\end{document}b1Σg+(v=0)←X3Σg−(v=0) perturbed by collisions with helium was studied theoretically using the impact approximation. To calculate the relaxation matrix, scattering calculations were performed on a newly computed helium-oxygen (\documentclass[12pt]{minimal}\begin{document}$b{^1\Sigma _g^+}$\end{document}b1Σg+) interaction potential as well as on a helium-oxygen (\documentclass[12pt]{minimal}\begin{document}$X{^3\Sigma _g^-}$\end{document}X3Σg−) interaction potential from the literature. The calculated integrated line cross sections and broadening coefficients are in good agreement with experimental results from the literature. Additionally, cavity ring-down experiments were performed in the wings of the spectral lines for a quantitative study of line-mixing, i.e., the redistribution of rotational line intensities by helium-oxygen collisions. It is shown that inclusion of line-mixing in the theory is required to reproduce the experimentally determined absolute absorption strengths as a function of the density of the helium gas.
Multiple solvent, N-methyl-2-pyrrolidone, acts as a novel adjuvant for enhancing cutaneous immune responses
Authors: Tatsuno Tomoko , Miyazaki Kentaro , Yamashiro Hiromichi 
Published: May 2014

Abstract
N-methyl-2-pyrrolidone (NMP) is known for its multi-solvent properties. However, its biological, especially immunological significance still remains to be elucidated. In this study, we show for the first time that NMP stimulates the skin immune system by activating epidermal Langerhans cells (LCs). In contrast with the placebo tape, when the NMP-containing adhesive tape was applied on murine skin, LCs were stimulated immediately. Activated LCs not only exhibited enhanced expression of major histocompatibility complex class II and morphological changes, including the loss of dendrites, but also migrated effectively to draining lymph nodes. In addition, application of the tyrosine-related protein-2 peptide, which is the cytotoxic T lymphocyte (CTL) epitope against B16 melanoma, in combination with the NMP tape, resulted in explosive expansion of specific CTLs in mouse spleens. Taken together, these results demonstrate a novel role of NMP as an adjuvant in percutaneous peptide immunization.
Establishment of a new method to quantitatively evaluate hyphal fusion ability in Aspergillus oryzae
Authors: Tsukasaki Wakako , Maruyama Jun-ichi , Kitamoto Katsuhiko 
Published: May 2014

Abstract
Hyphal fusion is involved in the formation of an interconnected colony in filamentous fungi, and it is the first process in sexual/parasexual reproduction. However, it was difficult to evaluate hyphal fusion efficiency due to the low frequency in Aspergillus oryzae in spite of its industrial significance. Here, we established a method to quantitatively evaluate the hyphal fusion ability of A. oryzae with mixed culture of two different auxotrophic strains, where the ratio of heterokaryotic conidia growing without the auxotrophic requirements reflects the hyphal fusion efficiency. By employing this method, it was demonstrated that AoSO and AoFus3 are required for hyphal fusion, and that hyphal fusion efficiency of A. oryzae was increased by depleting nitrogen source, including large amounts of carbon source, and adjusting pH to 7.0.
DualAligner
: a dual alignment-based strategy to align protein interaction networks
Authors: Seah Boon-Siew , Bhowmick Sourav S. , Dewey C. Forbes 
Published: May 2014

Abstract
Motivation: Given the growth of large-scale protein–protein interaction (PPI) networks obtained across multiple species and conditions, network alignment is now an important research problem. Network alignment performs comparative analysis across multiple PPI networks to understand their connections and relationships. However, PPI data in high-throughput experiments still suffer from significant false-positive and false-negatives rates. Consequently, high-confidence network alignment across entire PPI networks is not possible. At best, local network alignment attempts to alleviate this problem by completely ignoring low-confidence mappings; global network alignment, on the other hand, pairs all proteins regardless. To this end, we propose an alternative strategy: instead of full alignment across the entire network or completely ignoring low-confidence regions, we aim to perform highly specific protein-to-protein alignments where data confidence is high, and fall back on broader functional region-to-region alignment where detailed protein–protein alignment cannot be ascertained. The basic idea is to provide an alignment of multiple granularities to allow biological predictions at varying specificity.
Results: DualAligner performs dual network alignment , in which both region-to-region alignment, where whole subgraph of one network is aligned to subgraph of another, and protein-to-protein alignment, where individual proteins in networks are aligned to one another, are performed to achieve higher accuracy network alignments. Dual network alignment is achieved in DualAligner via background information provided by a combination of Gene Ontology annotation information and protein interaction network data. We tested DualAligner on the global networks from IntAct and demonstrated the superiority of our approach compared with state-of-the-art network alignment methods. We studied the effects of parameters in DualAligner in controlling the quality of the alignment. We also performed a case study that illustrates the utility of our approach.
Availability and implementation: http://www.cais.ntu.edu.sg/∼assourav/DualAligner/
Contact: seah0097@ntu.edu.sg or assourav@ntu.edu.sg
Supplementary information: Supplementary data are available at Bioinformatics online.
New aspects of IgA synthesis in the gut
Authors: Suzuki Keiichiro , Nakajima Akira 
Published: May 2014

Abstract
In mammals, the gastrointestinal tract is colonized by extremely dense and diverse bacterial communities that are beneficial for health. Maintenance of the complexity and the proper localization and distribution of gut bacteria is of prime importance because when disrupted, the microbial community attacks the host’s tissues and causes inflammatory reactions. Our immune system provides the necessary mechanisms to maintain the homeostatic balance between microbial communities and the host. IgA plays crucial roles in regulation of host–bacteria interactions in the gut. IgA is the most abundant immunoglobulin isotype in our body, mostly produced by the IgA plasma cells residing in the lamina propria of the small and large intestine. Although it was well known that IgA provides protection against pathogens, only recently has it become clear that IgA plays critical roles in regulation of bacterial communities in the gut in steady-state conditions. Here, we summarize recent progress in our understanding of the various mechanisms of IgA synthesis in multiple anatomical sites and discuss how IgA limits bacterial access to the internal milieu of the host.
Tannic acid-modified fatty amide anticorrosive coatings from Pongamia glabra oil
Authors: Alam Manawwer , M. Alandis Naser 
Published: May 2014

Purpose
– The purpose of this investigation was to develop sustainable resource-based anticorrosive coating material using Pongamia glabra seed oil and tannic acid (TA), as well as to improve the coating properties.

Design/methodology/approach
– TA-modified fatty amide diol was synthesized by condensation polymerization. First, Pongamia glabra seed oil was converted to fatty amide diol (Pongamia oil fatty amide, PFA) that was further modified by TA with different parts per hundred of resin (10, 15 and 20) to develop a polyether fatty amide (PFA-TA). The confirmation of reaction between TA and PFA was carried out using Fourier transform infrared spectroscopy. The thermal behavior of PFA-TA was studied by thermogravimetric analyses. Coatings of several PFA-TA resins were applied to steel (i.e. plain carbon steel) coupons to investigate their physico-mechanical and anticorrosive performance. The corrosion protection performance was observed using AC impedance and polarization tests.

Findings
– TA-modified fatty amide coatings showed the highest scratch hardness of 2.5 kg, flexibility (1/8 inch) and gloss at 45° was 60-62. Among all compositions, PFA-TA15 showed the best physico-mechanical and anticorrosion performance. Corrosion tests of coated panels were examined in different corrosive media (3.5 wt per cent HCl, 3.5 wt per cent NaOH and 5.0 wt per cent NaCl) using potentiodynamic polarization and AC impedance measurements. PFA-TA may find application as an eco-friendly protective coating, and thermal analyses revealed that it can be safely used up to 300°C.

Originality/value
– This paper provides the development of protective coatings for steel from non-edible seed oil and TA to utilize sustainable resources.
Corrosion control in CO2/H2S-produced water of offshore oil fields
Authors: Lu Yuan , Zhang Ying , Liu Zhenguo , Zhang Yong , Wang Chaoming , Guo Haijun 
Published: May 2014

Purpose
– In order to solve the corrosion problems in the South China Sea, the purpose of this paper was to study the main influences of corrosion including temperature, H2S content and corrosion inhibitor content in CO2/H2S oil field-produced water.

Design/methodology/approach
– The corrosion products formed on the steel surface were observed and analyzed using scanning electron microscope (SEM) and X-ray diffraction (XRD).

Findings
– The results indicate that temperature significantly influences the corrosion rate, which is a maximum at 70°C. The corrosion rate decreases as H2S content increases which is less than 10 mg/L, but then it increases rapidly. The FeCO3/Fe
x
S
y
protective film and a corrosion inhibition also were considered.

Research limitations/implications
– A mixture containing an imidazoline derivate and an organic amine can enhance the corrosion resistance of the corrosion product film.

Practical implications
– A mixture containing an imidazoline derivate and an organic amine can enhance the corrosion product film corrosion resistance.

Social implications
– Imidazoline is one kind of environmentally safe agent which can be used in the ocean.

Originality/value
– The corrosion can be controlled to a satisfactory extent in the presence of a mixture containing an imidazoline derivate and an organic amine.
The durability of sulfate resisting mortar with partial replacement by cement kiln dust
Authors: M. Kassim Moayad 
Published: May 2014

Purpose– The purpose of this study was to reuse cement kiln dust (CKD) in cement products and report the results of determining the long-term compression and flexural tensile strengths of mortars containing CKD as a partial replacement of sulfate-resistant cement (SRC). During the manufacturing of Portland cement, voluminous quantities of the byproduct dust are produced, which is commonly known as CKD. In the past decade, according to environmental requirements, many researchers have attempted to reuse CKD in cement products.Design/methodology/approach– The long-term compression and flexural tensile strengths of mortars containing CKD as a partial replacement of SRC were tested. The replacement ratios in this study were 0, 5, 10, 15 and 20 per cent. The specimens were exposed to a highly saline environment after normal curing in water for a 28-day period.Findings– The results indicated a slight increase in the strength of CKD–SRC mortar containing 10 per cent CKD and moderate sulfate resistance when the CKD ratio reached 20 per cent, as compared to the reference mortar. In addition, CKD did not adversely affect the properties of SRC mortar subjected to sulfate exposure, even after one year.Originality/value– The tests were inducted for the first time on SRC, and the new results can be used to produce an environmental-friendly concrete.
Institutional embeddedness renewal or overembeddedness
Authors: Zhang Qiang 
Published: May 2014

Purpose
– Viewing business groups as institutionally embedded agents, the purpose of this paper is to theoretically addresses the distinctions between institutional embeddedness renewal and overembeddedness, and empirically analyzes the proposed effecting mechanisms in the context of China.

Design/methodology/approach
– The paper predicts the specific performance effects accompanying the collective and local processes governing systematic institutional embeddedness phenomena, and examine the proposed hypotheses using a real experimental setting of Chinese business groups during the period of enterprise reform and stock market liberalization, employing data on 38 business groups in the textile industry from 2000 to 2008.

Findings
– The results of the econometric analysis support an optimistic view that business groups can strategically renew their embeddedness even in the late stages of market-oriented institutional transition as in China. Specifically: first, the positive effect of the self-enhancing isomorphic pressure around both the new and the old institutions implies the relative dominance of systematic institutional embeddedness renewal within business group communities; second, at the local level, institutional strategies promoting the market orientation of adopted organizational forms bring about not only positive but also negative effects, suggesting the need to manage a simultaneous significant risk of overembeddedness.

Originality/value
– The paper establishes an institutional strategy framework to predict potential effects associated with systematic institutional embeddedness phenomena, such as institutional embeddedness renewal and overembeddedness, in the context of market-oriented institutional transition.
Strategic orientation and dual innovative operation strategies
Authors: Aghajari Nezal , Amat Senin Aslan 
Published: May 2014

Purpose– The purpose of this paper is twofold. First, to address a key but neglected area of research in operation and strategy that is the association between strategic orientation of the firm and its innovation emphasis on the current and future operation initiatives. Second, to explore and examine respective performance implications of these two kinds of operation strategies.Design/methodology/approach– Data from a carefully designed and conducted survey of Malaysia manufacturing SMEs were analysed using a structural equation modelling approach.Findings– Findings suggest that strategic innovation is strongly associated with both types of innovative operation strategies and they bring about different operational and market performance outcomes for the firm. This sheds light on a new framework for understanding the strategic architecture of innovation in operation strategies.Research limitations/implications– This study was limited to the small manufacturing firms in Malaysia. As a result, to assess its generalizability it can be replicated in other sectors and also other countries.Practical implications– Several managerial implications emanate from this research. Most notably is the notion that strategic orientation is a key antecedent of innovation in operation strategies and in particular, it affects both current and future related innovative initiatives. This indicates that executives of manufacturing firms must align their innovative moves with their strategic mind-set to achieve their desired outcomes both operationally and financially.Originality/value– To the best of knowledge of the author and based on a comprehensive review of past research, this study is original in two ways: first it is the first research that links strategic orientation with dual innovative operation strategies and second it is the first attempt to investigate respective operational and financial outcomes of these associations separately. This framework adds new insights and original value to several bodies of knowledge.