bluuebunny/crossref_metadata_2025_split huggingface dataset:
Examining national tourism brand image: content analysis of Lonely Planet Korea
Authors: Youn Kim Hee , Yoon Ji‐Hwan 
Published: June 2013

PurposeThe purpose of this paper is to analyze the Korea tourism brand image in a popular tour guidebook, Lonely Planet Korea and to provide an objective insight for examining destination image.Design/methodology/approachTo achieve this goal, this study used content analysis to analyze the Korea tourism brand image.FindingsOverall, 200,435 words were selected. The frequency of words was highly related to transportation and famous attractions. Moreover, to evaluate the value of the Korea tourism brand image, only adjectives in context were extracted. In total, 2,716 adjectives in each category were examined. The Korea tourism brand image was positive in that “good” adjectives were the most frequently selected. Furthermore, value properties based on The Lasswell Value Dictionary were examined. The value of words also supported the results of the content analysis of adjectives. The results of correspondence analysis found that the “outdoor” category was separately positioned with “old” adjectives.Practical implicationsBased on the results of content analysis by category, selected adjectives reflected current Korean tourism and hospitality problems.Originality/valueThe paper suggests implications that can be used to improve the Korea tourism brand image.
The physicochemical, microbiological, organoleptic properties and antioxidant activities of functional cream cheeses fortified with lutein
Authors: Tokuşoğlu Özlem 
Published: June 2013

Functional cream cheeses were manufactured with 0, 0.5, 0.75, 1.5 and 3.0 mg lutein/100 g serving. Cheeses were monitored at 0, 1, 3, 5 and 7 weeks of storage. The pH value of an average of 5.5 provides softness and strong taste for the product. Descriptive sensory properties of lutein‐fortified cream cheeses contained milky, buttery, salty and whey flavours. Cheese flavour was not affected by the differences in lutein levels. HPLC detection showed that lutein remained as stabile throughout about 6 weeks of storage. Physicochemical, microbiological and organoleptic data showed that 1.5 mg of fortification has preferred overall quality, and the best shelf life was recorded at week 3 of storage (P < 0.05).
Hospital Admissions for Alcohol Use Disorders Before, During, and After Pregnancy: A Study Based on Linked Population Data in New South Wales, Australia
Authors: Xu Fenglian , Bonello Michelle , Burns Lucy , Austin Marie‐Paule , Li Zhuoyang , Sullivan Elizabeth 
Published: June 2013

BackgroundAlcohol use disorders (AUD) during pregnancy can have profound lifelong effects on the baby, including fetal alcohol spectrum disorders (FASD). Hospital admission for AUD during pregnancy provides an opportunity for intervention. Characterization of women along the AUD spectrum during pregnancy aids the development of prevention strategies, policy, and clinical management guidelines aimed at this population. This study describes the hospital admission levels for AUD between the sixth month before pregnancy and the first year after birth and explores risk factors associated with the hospital admissions.MethodsThis study was based on linked population data between 2002 and 2005 using the New South Wales (NSW) Midwives Data Collection (MDC) and the NSW Admitted Patients Data Collection (APDC), Australia. The study subjects included primiparous mothers who were admitted to hospital in the period from the sixth month before pregnancy to 1 year after birth with at least 1 of the following diagnoses (ICD‐10‐AM): mental and behavioral disorders due to the use of alcohol (MBDA) (F10.0–10.9); toxic effects of alcohol (T51.0–51.9); maternal care for suspected damage to fetus from alcohol (O35.4); or alcohol rehabilitation (Z50.2).ResultsA total of 175 new mothers had 287 hospital admissions with the principal or stay AUD diagnoses during the study period in NSW. Of the 287 admissions, 181 admissions (63.07%) were reported for an alcohol‐related disorder as the principal diagnosis. The hospital admission rate for AUD was 1.76/1,000 person‐years (PY) (95% CI: 1.45 to 2.07) during the 6 months prepregnancy. The rate decreased to 0.49/1,000 PY (95% CI: 0.36 to 0.63) during pregnancy and to 0.82/1,000 PY (95% CI: 0.67 to 0.97) in the first year after birth. Women who smoked during pregnancy, lived in a remote area and were younger than 25 years, were more likely to be admitted to hospital with AUD diagnoses. Women in the middle disadvantaged quintile and born in other countries were less likely to be admitted to hospital with AUD diagnoses.ConclusionsHospital admission for AUD decreased significantly in pregnancy and the first year postpartum compared to the prepregnancy period.
A randomised comparison of lidocaine 2% gel and proparacaine 0.5% eye drops in paediatric squint surgery
Authors: Sinha R. , Chandralekha  , Batra M. , Ray B. R. , Mohan V. K. , Saxena R. 
Published: June 2013

SummaryWe conducted a randomised trial comparing lidocaine 2% gel with proparacaine 0.5% eye drops in children having elective squint surgery. One hundred and forty children aged between 3 and 14 years were recruited. The requirement for intra‐operative fentanyl and postoperative ibuprofen was significantly less in the lidocaine group compared with the proparacaine group (1 (1.7%) vs 12 (18.5%), p = 0.002 and 16 (27.6%) 38 (58.5%), p = 0.001, respectively). The incidence of postoperative nausea and vomiting was significantly less in the lidocaine group compared with the proparacaine group (6 (10.3%) vs 16 (24.6%), p = 0.04). There were no differences between the groups in terms of incidence and severity of the oculocardiac reflex. We conclude that, compared with proparacaine 0.5% eye drops, a single application of lidocaine 2% gel improves peri‐operative analgesia and reduces the incidence of postoperative nausea and vomiting in elective paediatric squint surgery.
Developmentalities and Donor–NGO Relations: Contesting Foreign Aid Policies in New Zealand/Aotearoa
Authors: McGregor Andrew , Challies Edward , Overton John , Sentes Lee 
Published: June 2013

AbstractIn this paper we draw on the concept of governmentality to examine the relationships between donors and northern non‐governmental organisations (NGOs) during moments of policy change. Our case study comes from New Zealand/Aotearoa where a change in government has seen aid policy shift from poverty alleviation to sustainable economic development. We detail three mechanisms through which the government sought to normalise this change: changes in language and fields of visibility; institutional reform; and funding delays and cuts. Far from being complete, however, we also trace how some NGOs contested the new agenda through engaging in the practice of politics and how, at least temporarily, new more politicised development subjectivities were created. While our study raises awkward questions about the autonomy of NGOs within current funding environments, we also emphasise the productive possibilities and openings that emerge as one set of development ideas and techniques, or developmentalities, shifts to another.
Obese women's reasons for not attending a weight management service during pregnancy
Authors: Olander Ellinor K. , Atkinson Lou 
Published: June 2013

AbstractEvaluations of services targeting obese women's gestational weight gain often report low uptake. Thus it is important to elicit the reasons why obese pregnant women decline to participate in these services and to identify their barriers to participation. Sixteen obese pregnant and postnatal women were interviewed regarding their reasons for declining a group‐based service targeting their gestational weight gain. All interviews were recorded, transcribed verbatim and analyzed thematically. Both pragmatic and motivational barriers were identified. The most common practical reasons for not attending the service were its inconvenient location and time, and feeling unable to attend due to work commitments. Pregnancy‐specific barriers included decreased mobility and feeling unwell. Motivational barriers included lack of interest and not wanting to focus on one's weight in pregnancy. These findings highlight issues that need to be taken into consideration when designing group‐based weight management services for this population.
Adherence, persistence and switch rates for anticholinergic drugs used for overactive bladder in women: data from the Norwegian Prescription Database
Authors: Mauseth Siri A. , Skurtveit Svetlana , Spigset Olav 
Published: June 2013

AbstractObjectiveTo investigate the pattern of use of anticholinergic drugs for overactive bladder among women in Norway with regard to persistence, adherence and switch rates.DesignObservational study.Setting and sampleData from the Norwegian Prescription Database on prescriptions for tolterodine, solifenacin, darifenacin and fesoterodine filled in Norwegian pharmacies from 1 January 2004 to 31 December 2010.Methods and main outcome measuresData from the database were analysed at an individual level, and drug persistence, discontinuation rates and switch rates during a follow‐up period of 365 days after the first prescription were calculated.ResultsOverall 1‐year persistence for new users was 38.0%. Within the same period, a total of 10.3% switched from the index drug to another drug in the same group, whereas 51.7% discontinued without switching. Users of solifenacin and tolterodine were somewhat more persistent than users of darifenacin and fesoterodine. Persistence was lowest (20.9%) in the age group 18–39 years, increased with age and was highest in the age groups 70–79 years and 80 years and above (43.5 and 43.3%, respectively). In total, 31.9% filled only one prescription of the drug and, of these, only one of four women switched to another drug. The proportion who were adherent during treatment was 60.4%.ConclusionsThe discontinuation rate for anticholinergic drugs for overactive bladder in women is high. The reasons why patients stop using them remain obscure but could be related both to a limited clinical effect and an unacceptable adverse effect burden.
Influence of nutritional deficiency on prognosis of renal cell carcinoma (RCC)
Authors: Ko Kyungtae , Park Young H. , Lee Jeong W. , Ku Ja H. , Kwak Cheol , Kim Hyeon H. 
Published: June 2013

Objective
To evaluate the prognosis of patients with renal cell carcinoma (RCC) by nutritional status defined by body mass index (BMI), serum albumin and cholesterol.
Patients and Methods
This study retrospectively enrolled 1437 patients who underwent radical nephrectomy (932) or partial nephrectomy (505) for RCC.
We assigned nutritional status according to the presence of none or one nutritional risk factor (control group) and two or all three of the following nutritional risk factors (nutritional deficiency group).
The nutritional factors and thresholds were preoperative albumin level (<3.5 g/dL), preoperative cholesterol level (<220 mg/dL), and preoperative BMI (<23 kg/m2)
Results
The patients' mean (sd) age was 55.23 (12.41) years and BMI was 24.36 (3.17) kg/m2. The mean (sd) serum cholesterol level was 180.07 (38.24) mg/dL, and the albumin level was 4.2 (0.45) g/dL.
In all, 141 (9.8%) patients had none of the nutritional deficiency criteria, 802 (55.8%) had one, 429 (29.9%) had two, and 65 (4.5%) had all three.
Clinicopathological variables, i.e. female gender, high tumour stage, positive lymph node metastasis, positive distant metastasis, high nuclear grade and non‐clear cell type histopathology were associated with the nutritional deficiency group.
In multivariate Cox analysis, nutritional deficiency was an independent predictor for RCC recurrence (hazard ratio [HR] 1.39, 95% confidence interval [CI] 1.05–1.83, P = 0.020) and RCC‐related mortality (HR 2.06, 95% CI 1.39–3.03, P < 0.001).
Conclusion
Nutritional deficiency defined by BMI, serum albumin and cholesterol is an important factor that predicts postoperative prognosis of patients with RCC who have undergone radical or partial nephrectomy.
Renal tumour nephrometry score does not correlate with the risk of radiofrequency ablation complications
Authors: Seideman Casey A. , Gahan Jeffrey , Weaver Matthew , Olweny Ephrem O. , Richter Michael , Chan Danny , Cadeddu Jeffrey A. 
Published: June 2013

Objectives
To assess whether the R.E.N.A.L. nephrometry score (consists of [R]adius [tumour size as maximal diameter], [E]xophytic/endophytic properties of the tumour, [N]earness of tumour deepest portion to the collecting system or sinus, [A]nterior [a]/posterior [p] descriptor and the [L]ocation relative to the polar line) is associated with complication risk in patients that have radiofrequency ablation (RFA) for small renal masses (SRMs).
To evaluate a standardised system for predicting complication risks which has not been studied.
Patients and Methods
We reviewed the records of all patients who underwent RFA at our institution between May 2001 and May 2011.
RFA was performed using a temperature‐based system and a 25‐G nine‐tine array needle probe. Patients with preoperative imaging available for R.E.N.A.L. nephrometry scoring were included.
R.E.N.A.L. composite scores, tertile stratification and preoperative patient characteristics were analysed for significance in relation to complications.
Complications were defined using the Clavien‐Dindo classification system.
Results
In all, 199 patients had preoperative R.E.N.A.L. nephrometry scores available; 170 underwent percutaneous RFA and 29 laparoscopic RFA.
The mean (range) American Society of Anesthesiologists (ASA) score was 2.6 (1–4). The mean (range) tumour size was 2.4 (0.7–5.4) cm.
Overall, 14 complications were identified; 10 minor (Clavien I–II) and four major (Clavien III–IV). There was no significant association between complications and R.E.N.A.L. nephrometry score, R.E.N.A.L. nephrometry tertiles, tumour diameter, tumour location or ASA score (P > 0.05).
Conclusion
R.E.N.A.L. nephrometry scoring fails to predict complications of RFA for SRMs when using a temperature‐based nine‐tine array probe.
Trends in renal function after radical nephrectomy: a multicentre analysis
Authors: Chung Jae S. , Son Nak H. , Byun Seok‐Soo , Lee Sang E. , Hong Sung K. , Jeong Chang W. , Lee Sang C. , Chae Dong‐Wan , Choi Won S. , Park Yong H. , Hong Sung H. , Kim Yong J. , Kang Seok H. 
Published: June 2013

Objective
To evaluate serial changes in renal function by investigating various clinical factors after radical nephrectomy (RN).
Patients and Methods
The study population consisted of 2068 consecutive patients who were treated at multiple institutions by RN for renal cortical tumour without metastasis between 1999 and 2011.
We measured the serial change in estimated glomerular filtration rate (eGFR) and clinical factors during a 60‐month follow‐up period.
The changes in eGFR over time were analysed according to baseline eGFR (eGFR ≥60 and 15–59 mL/min/1.73m2) using a linear mixed model.
The independent prognostic value of various clinical factors on the increase in eGFR was ascertained by multivariate mixed regression model.
Results
Overall, there was a subsequent restoration of renal function over the 60 months.
The slope for the relationship between the eGFR and the time since RN was 0.082 (95% confidence interval [CI] 0.039–0.104; P < 0.001) and 0.053 (95% CI 0.006–0.100; P = 0.038) in each baseline group, indicating that each month after RN was associated with an increase in eGFR of 0.082 and 0.053 mL/min/1.73m2, respectively.
When we analysed renal function based on various factors, postoperative eGFR of patients with diabetes mellitus, old age (≥70 years) or a preoperative eGFR of <30 mL/min/1.73 m2, was decreased or maintained at a certain level without any improvement in renal function.
Preoperative predictors of an increase in eGFR after RN were young age, no DM, no hypertension, a preoperative eGFR of ≥30 mL/min/1.73m2 and time after surgery (≥36 months).
Conclusions
Renal function recovered continuously during the 60‐month follow‐up period after RN.
However, the trends in functional recovery change were different according to various clinical factors and such information should be discussed with patients when being counselled about their treatment for renal cell carcinoma (RCC).
Yonsei nomogram to predict lymph node invasion in Asian men with prostate cancer during robotic era
Authors: Kim Kwang Hyun , Lim Sey Kiat , Kim Ha Yan , Han Woong Kyu , Choi Young Deuk , Chung Byung Ha , Hong Sung Joon , Rha Koon Ho 
Published: June 2013

Objective
To develop a novel nomogram to predict lymph node invasion (LNI) in Asian men undergoing radical prostatectomy (RP) and pelvic LN dissection (PLND) for localised prostate cancer.
Patients and Methods
The patient cohort included 541 patients who underwent robot‐assisted RP and PLND by a single surgeon between January 2008 and December 2011.
Patients with dissection of <10 LNs, prostate‐specific antigen (PSA) levels of >50 ng/mL, incomplete biopsy data, and treatment with neoadjuvant therapy were excluded.
Results
The median (interquartile range) number of LNs removed was 17 (14–22) and 45 patients (8.3%) had LN metastases. On multivariate logistic regression analysis, PSA level, clinical stage and Gleason score were independent predictors of LNI.
The bootstrap corrected area under curve of the model incorporating PSA level, clinical stage, and biopsy Gleason score was 0.883.
With a cutoff value of 4%, PLND could be omitted in 326 patients (60.2%), missing only two patients (4.4%) with LNI. The sensitivity, specificity, positive predictive value and negative predictive value were 95.6%, 65.3%, 20.0% and 99.4%, respectively.
Conclusions
We report a nomogram to predict LNI in Asian men with prostate cancer. The model demonstrated high accuracy and could be used for counselling patients and the selection of candidates for PLND.
Indications, results and safety profile of transperineal sector biopsies (TPSB) of the prostate: a single centre experience of 634 cases
Authors: Vyas Lona , Acher Peter , Kinsella Janette , Challacombe Ben , Chang Richard T.M. , Sturch Paul , Cahill Declan , Chandra Ashish , Popert Richard 
Published: June 2013

Objective
To describe a protocol for transperineal sector biopsies (TPSB) of the prostate and present the clinical experience of this technique in a UK population.
Patients and Methods
A retrospective review of a single‐centre experience of TPSB approach was undertaken that preferentially, but not exclusively, targeted the peripheral zone of the prostate with 24–38 cores using a ‘sector plan’. Procedures were carried out under general anaesthetic in most patients.
Between January 2007 and August 2011, 634 consecutive patients underwent TPSB for the following indications: prior negative transrectal biopsy (TRB; 174 men); primary biopsy in men at risk of sepsis (153); further evaluation after low‐risk disease diagnosed based on a 12‐core TRB (307).
Results
Prostate cancer was found in 36% of men after a negative TRB; 17% of these had disease solely in anterior sectors. As a primary diagnostic strategy, prostate cancer was diagnosed in 54% of men (median PSA level was 7.4 ng/mL).
Of men with Gleason 3+3 disease on TRB, 29% were upgraded and went on to have radical treatment.
Postoperative urinary retention occurred in 11 (1.7%) men, two secondary to clots. Per‐urethral bleeding requiring hospital stay occurred in two men. There were no cases of urosepsis.
Conclusions
TPSB of the prostate has a role in defining disease previously missed or under‐diagnosed by TRB. The procedure has low morbidity.
Benefit in regionalisation of care for patients treated with radical cystectomy: a nationwide inpatient sample analysis
Authors: Ravi Praful , Bianchi Marco , Hansen Jens , Trinh Quoc‐Dien , Tian Zhe , Meskawi Malek , Abdollah Firas , Briganti Alberto , Shariat Shahrokh F. , Perrotte Paul , Montorsi Francesco , Karakiewicz Pierre I. , Sun Maxine 
Published: June 2013

Objective
To quantify in absolute terms the potential benefit of regionalisation of care from low‐ to high‐volume hospitals.
Patients and Methods
Patients with a primary diagnosis of bladder cancer treated with radical cystectomy (RC) were identified within the Nationwide Inpatient Sample, a retrospective observational population‐based cohort of the USA, between 1998 and 2009.
Intraoperative and postoperative complications, blood transfusions, prolonged length of stay, and in‐hospital mortality rates represented the outcomes of interest.
Potentially avoidable outcomes were calculated by subtracting predicted rates (i.e. estimated outcomes if care was delivered at a high‐volume hospital) from observed rates (i.e. actual observed outcomes after care delivered at a low‐volume hospital).
Multivariable logistic regression models and number needed to treat were generated.
Results
Patients treated at high‐volume hospitals had lower odds of complications during hospitalisation than those treated in low‐volume hospitals.
Potentially avoidable intraoperative complications, postoperative complications, blood transfusions, prolonged hospitalisation, and in‐hospital mortality rates were 0.6, 7.4, 2.8, 9.4, and 2.0%, respectively.
This corresponds to a number needed to redirect from low‐ to high‐volume hospitals in order to avoid one adverse event of 166, 14, 36, 11 and 50, respectively.
Conclusion
This is the first report to quantify the potential benefit of regionalisation of RC for muscle‐invasive bladder cancer to high‐volume hospitals.
Chemical‐ and radiation‐induced haemorrhagic cystitis: current treatments and challenges
Authors: Payne Heather , Adamson Andrew , Bahl Amit , Borwell Jonathan , Dodds David , Heath Catherine , Huddart Robert , McMenemin Rhona , Patel Prashant , Peters John L. , Thompson Andrew 
Published: June 2013

To review the published data on predisposing risk factors for cancer treatment‐induced haemorrhagic cystitis (HC) and the evidence for the different preventive and therapeutic measures that have been used in order to help clinicians optimally define and manage this potentially serious condition.
Despite recognition that HC can be a significant complication of cancer treatment, there is currently a lack of UK‐led guidelines available on how it should optimally be defined and managed.
A systematic literature review was undertaken to evaluate the evidence for preventative measures and treatment options in the management of cancer treatment‐induced HC.
There is a wide range of reported incidence due to several factors including variability in study design and quality, the type of causal agent, the grading of bleeding, and discrepancies in definition criteria.
The most frequently reported causal factors are radiotherapy to the pelvic area, where HC has been reported in up to 20% of patients, and treatment with cyclophosphamide and bacillus Calmette‐Guérin, where the incidence has been reported as up to 30%. Mesna (2‐mercaptoethane sodium sulphonate), hyperhydration and bladder irrigation have been the most frequently used prophylactic measures to prevent treatment‐related cystitis, but are not always effective. Cranberry juice is widely cited as a preventative measure and sodium pentosanpolysulphate as a treatment, although the evidence for both is very limited.
The best evidence exists for intravesical hyaluronic acid as an effective preventative and active treatment, and for hyperbaric oxygen as an equally effective treatment option.
The lack of robust data and variability in treatment strategies used highlights the need for further research, as well as best practice guidance and consensus on the management of HC.