bluuebunny/crossref_metadata_2025_split huggingface dataset:
Incidence of malignant mesothelioma of the pleura in Québec and Canada from 1984 to 2007, and projections from 2008 to 2032
Authors: Krupoves Alfreda , Camus Michel , De Guire Louise 
Published: March 2015

BackgroundContinuous increase in male incidence of malignant mesothelioma of the pleura (MMP) despite the drop of asbestos production since 1980 in Québec motivated this study aiming to assess when the rates of MMP will decline.MethodsAge‐standardized rates and trends were estimated over the 1984–2007 period by sex for Québec versus “Canada‐excluding‐Québec” (Can‐Qc). An age‐cohort regression was used to make projections for 2008–2032.ResultsAverage rates of MMP in Québec men and women were significantly higher than in Can‐Qc. Projected rates peak between 2003 and 2012 in all four study populations and decline thereafter.ConclusionThe higher MMP rates and observed/projected time patterns in Québec men are consistent with past asbestos production and occupational exposures. The excess in Québec women may also be explained by domestic and, for some, by neighborhood exposures. To pursue the decrease in MMP rates beyond 2032, efforts to reduce asbestos exposure should be maintained. Am. J. Ind. Med. 58:473–482, 2015. © 2015 Wiley Periodicals, Inc.
Ein fluoriertes Detergens für Membranprotein‐Anwendungen
Authors: Frotscher Erik , Danielczak Bartholomäus , Vargas Carolyn , Meister Annette , Durand Grégory , Keller Sandro 
Published: March 2015

AbstractTenside mit fluorierten Kohlenstoffketten stellen eine vielversprechende milde Alternative zu konventionellen, vollständig hydrierten Detergentien für die Solubilisierung und Handhabung integraler Membranproteine dar. Aufgrund ihrer Inertheit gegenüber Lipidmembranen blieben sie bisher aber von beschränktem Nutzen für solche Anwendungen, in denen eine detergensähnliche Aktivität benötigt wird. Hier zeigen wir, dass Fluorierung an sich Detergensaktivität nicht ausschließt, wie an einem als F6OM bezeichneten fluorierten Octylmaltosid‐Derivat veranschaulicht wird. Diese nichtionische Verbindung wechselwirkt mit und solubilisiert Phospholipidvesikel in detergensähnlicher Weise, ohne jedoch die Membranordnung unterhalb der Solubilisierungsgrenze zu beeinträchtigen. Dank dieser sanften und unüblichen Detergensaktivität ist F6OM im Gegensatz zu einem lipophoben fluorierten Tensid in der Lage, die funktionelle Rückfaltung eines integralen Membranenzyms durch Förderung der Membraninsertion in Abwesenheit von Mizellen zu unterstützen.
Enhanced thermoelectric performance by alcoholic solvents effects in highly conductive benzenesulfonate‐doped poly(3,4‐ethylenedioxythiophene)/graphene composites
Authors: Ju Hyun , Kim Myeongjin , Kim Jooheon 
Published: March 2015

ABSTRACTBenzenesulfonate‐doped poly(3,4‐ethylenedioxythiophene) (PEDOT‐Bzs)/graphene thermoelectric (TE) composites with various graphene filler contents were synthesized in five different kinds of solvents. Dodecylbenzenesulfonic acid (DBSA) was used to achieve good dispersion of graphene into the PEDOT matrix. Among the synthesized PEDOT materials, the one synthesized in methanol (PEDOT‐MeOH) had the highest electrical conductivity. X‐ray photoelectron spectroscopy (XPS) analysis showed almost the same charge carrier concentration for all PEDOT materials. However, the X‐ray diffraction (XRD) analysis highlighted the enhancement of PEDOT chain stacking by shorter‐chain alcoholic solvents, as a result of which the carrier mobility and electrical conductivity were increased. The electrical conductivity and the Seebeck coefficient of the PEDOT/graphene composites were significantly improved with increasing the graphene content, which strongly depended on increased carrier mobility. The thermal conductivity of the composites exhibited relatively small changes, attributed to phonon scattering effects. The maximum TE efficiency of the PEDOT‐MeOH/graphene composite with 75 wt % graphene showed a substantially improved value of 1.9 × 10−2, higher than that of the other PEDOT/graphene composites. © 2015 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2015, 132, 42107.
Technical Limitations on the Use of Traditional Magnetic Resonance Imaging in the Evaluation of Mummified Remains: A View From a Hands‐On Radiologic Technologist's Perspective
Authors: Posh John C. 
Published: March 2015

ABSTRACTNoninvasive imaging tools have been the standard in mummy studies for several decades focusing primarily on CT scan technology. Although magnetic resonance imaging (MRI) has been attempted on mummified tissues on numerous occasions these have met with varying degrees of success. The basic physics of MRI are reviewed here with an emphasis on how the physics limit the success of MRI in mummified tissues. Adjusting MRI parameters can enhance the images produced with a summary table that considers the effect of adjustments within these parameters. Several mummies with varying methods of preservation have been included in this study and MRI images presented and the results are critically assessed. MRI can generate basic images in most tissues even when significantly desiccated. Using an understanding of the essentials of MRI physics, with the adjustment of MRI parameters, the data acquisition process can be enhanced to create the best possible images. When successfully applied, MRI generated images can allow for the resolution of soft tissue differences, especially of collapsed internal organ masses, even in dehydrated mummies that are much less effectively rendered in CT scans. Anat Rec, 298:1116–1124, 2015. © 2015 Wiley Periodicals, Inc.
The classroom experiences of pupils with special educational needs in mainstream primary schools—1976 to 2012. What do data from systematic observation studies reveal about pupils’ educational experiences over time?
Authors: Webster Rob 
Published: March 2015

This paper presents results of an analysis of primary‐aged pupils’ educational experiences over a 35 year period. Data drawn from a set of large‐scale systematic observation studies, conducted in the UK between 1976 and 2012, are used to describe pupils’ average classroom experiences at six points in time over this period. These data are then used as markers for comparing the experiences of a subset of pupils—those with special educational needs (SEN)—over the same period. Results for the average pupil show an increase over time in the proportion of time spent interacting with teachers and peers. In contrast, relative to these non‐SEN pupils, those with SEN have experienced a more moderate increase in the proportion of time spent interacting with the teacher, and almost no change in the amount of time spent interacting with peers and in whole class teaching contexts. The increase in the number of teaching assistants in mainstream primary settings, employed and deployed to assist the learning and inclusion of pupils with SEN, is identified as a key observable influence on the difference between the classroom experiences of pupils with and without SEN over time. This paper additionally defends the use of systematic observation methods, and concludes that the broad, but stable, measures of activity and behaviour, plus the rigorous approach to data collection it provides, are necessary for painting objective, descriptive and retrospective pictures of classroom life that can elude other research techniques.
Investigation on the interaction of nanoAg with Cu–Zn SOD
Authors: Zhang Bin , Yu Lei , Zhang Ruijing , Liu Yang , Liu Rutao 
Published: March 2015

AbstractSilver nanoparticles (nanoAg) are used more and more widely, particularly because of their antimicrobial properties. The effect of exposure to nanoAg on the structure of superoxide dismutase (SOD) was thoroughly investigated using fluorescence measurements, synchronous fluorescence spectroscopy, steady‐state and time‐resolved fluorescence quenching measurements, UV/Vis absorption spectroscopy, resonance light scattering (RLS), circular dichroism (CD), isothermal titration calorimetry (ITC) and high‐resolution transmission electron microscopy (HRTEM). Through van der Waal's force, nanoAg interacted with Cu–Zn SOD and influenced the active site by inducing structural changes, which influenced the function of SOD. The fluorescence studies show that both static and dynamic quenching processes occur. This paper provides reference data for toxicological studies of nanoAg, which are important in the future development of nanotechnology. Copyright © 2015 John Wiley & Sons, Ltd.
RORA and posttraumatic stress trajectories: main effects and interactions with childhood physical abuse history
Authors: Lowe Sarah R. , Meyers Jacquelyn L. , Galea Sandro , Aiello Allison E. , Uddin Monica , Wildman Derek E. , Koenen Karestan C. 
Published: March 2015

AbstractBackgroundLongitudinal studies of posttraumatic stress (PTS) have documented environmental factors as predictors of trajectories of higher, versus lower, symptoms, among them experiences of childhood physical abuse. Although it is now well‐accepted that genes and environments jointly shape the risk of PTS, no published studies have investigated genes, or gene‐by‐environment interactions (GxEs), as predictors of PTS trajectories. The purpose of this study was to fill this gap.Methods and MaterialsWe examined associations between variants of the retinoid‐related orphan receptor alpha (RORA) gene and trajectory membership among a sample of predominantly non‐Hispanic Black urban adults (N = 473). The RORA gene was selected based on its association with posttraumatic stress disorder (PTSD) in the first PTSD genome wide association study. Additionally, we explored GxEs between RORA variants and childhood physical abuse history.ResultsWe found that the minor allele of the RORA SNP rs893290 was a significant predictor of membership in a trajectory of consistently high PTS, relatively to a trajectory of consistently low PTS. Additionally, the GxE of rs893290 with childhood physical abuse was significant. Decomposition of the interaction showed that minor allele frequency was more strongly associated with membership in consistently high or decreasing PTS trajectories, relative to a consistently low PTS trajectory, among participants with higher levels of childhood physical abuse.ConclusionThe results of the study provide preliminary evidence that variation in the RORA gene is associated with membership in trajectories of higher PTS and that these associations are stronger among persons exposed to childhood physical abuse. Replication and analysis of functional data are needed to further our understanding of how RORA relates to PTS trajectories.
Magnetic Nanohybrids Loaded with Bimetal Core–Shell–Shell Nanorods for Bacteria Capture, Separation, and Near‐Infrared Photothermal Treatment
Authors: Hu Bo , Wang Ning , Han Lu , Chen Ming‐Li , Wang Jian‐Hua 
Published: March 2015

AbstractA novel antimicrobial nanohybrid based on near‐infrared (NIR) photothermal conversion is designed for bacteria capture, separation, and sterilization (killing). Positively charged magnetic reduced graphene oxide with modification by polyethylenimine (rGO–Fe3O4–PEI) is prepared and then loaded with core–shell–shell Au–Ag–Au nanorods to construct the nanohybrid rGO–Fe3O4–Au–Ag–Au. NIR laser irradiation melts the outer Au shell and exposes the inner Ag shell, which facilitates controlled release of the silver shell. The nanohybrids combine physical photothermal sterilization as a result of the outer Au shell with the antibacterial effect of the inner Ag shell. In addition, the nanohybrid exhibits high heat conductivity because of the rGO and rapid magnetic‐separation capability that is attributable to Fe3O4. The nanohybrid provides a significant improvement of bactericidal efficiency with respect to bare Au–Ag–Au nanorods and facilitates the isolation of bacteria from sample matrixes. A concentration of 25 μg mL−1 of nanohybrid causes 100 % capture and separation of Escherichia coli O157:H7 (1×108 cfu mL−1) from an aqueous medium in 10 min. In addition, it causes a 22 °C temperature rise for the surrounding solution under NIR irradiation (785 nm, 50 mW cm−2) for 10 min. With magnetic separation, 30 μg mL−1 of nanohybrid results in a 100 % killing rate for E. coli O157:H7 cells. The facile bacteria separation and photothermal sterilization is potentially feasible for environmental and/or clinical treatment.
Micro‐MoS2 with Excellent Reversible Sodium‐Ion Storage
Authors: Wang Xuefeng , Li Yejing , Guan Zhaoruxin , Wang Zhaoxiang , Chen Liquan 
Published: March 2015

AbstractLow storage capacity and poor cycling stability are the main drawbacks of the electrode materials for sodium‐ion (Na‐ion) batteries, due to the large radius of the Na ion. Here we show that micro‐structured molybdenum disulfide (MoS2) can exhibit high storage capacity and excellent cycling and rate performances as an anode material for Na‐ion batteries by controlling its intercalation depth and optimizing the binder. The former method is to preserve the layered structure of MoS2, whereas the latter maintains the integrity of the electrode during cycling. A reversible capacity of 90 mAh g−1 is obtained on a potential plateau feature when less than 0.5 Na per formula unit is intercalated into micro‐MoS2. The fully discharged electrode with sodium alginate (NaAlg) binder delivers a high reversible capacity of 420 mAh g−1. Both cells show excellent cycling performance. These findings indicate that metal chalcogenides, for example, MoS2, can be promising Na‐storage materials if their operation potential range and the binder can be appropriately optimized.
A Tris(triazolate) Ligand for a Highly Active and Magnetically Recoverable Palladium Catalyst of Selective Alcohol Oxidation Using Air at Atmospheric Pressure
Authors: Wang Dong , Deraedt Christophe , Salmon Lionel , Labrugère Christine , Etienne Laetitia , Ruiz Jaime , Astruc Didier 
Published: March 2015

AbstractHigh efficiency and selectivity, easy magnetic recovery and recycling, and use of air as the oxidant at atmospheric pressure are major objectives for oxidation catalysis in terms of sustainable and green processes. A tris(triazolyl) ligand, so far only used in copper‐catalyzed alkyne azide cycloadditions, was found to be extremely efficient in SiO2/γ‐Fe2O3‐immobilized palladium complexes. It was characterized by inductively coupled plasma (ICP) analysis, transmission electron microscopy (TEM), scanning transmission electron microscopy (STEM), energy‐dispersive X‐ray spectroscopy (EDX), and X‐ray photoelectron spectra (XPS) and found to fulfill the combined conditions for the selective oxidation of alcohols to aldehydes and ketones.
Simultaneous Visualization of Multiple mRNAs and Matrix Metalloproteinases in Living Cells Using a Fluorescence Nanoprobe
Authors: Pan Wei , Yang Huijun , Li Na , Yang Limin , Tang Bo 
Published: March 2015

AbstractSimultaneous monitoring of multiple tumour markers is of great significance for improving the accuracy of early cancer detection. In this study, a fluorescence nanoprobe has been prepared that can simultaneously monitor and visualize multiple mRNAs and matrix metalloproteinases (MMPs) in living cells. Confocal fluorescence imaging results indicate that the nanoprobe could effectively distinguish between cancer cells and normal cells even if one tumour maker of normal cells was overexpressed. Furthermore, it can detect changes in the expression levels of mRNAs and MMPs in living cells. The current approach could provide new tools for early cancer detection and monitoring the changes in expression levels of biomarkers during tumour progression.
Binding Energies of the π‐Stacked Anisole Dimer: New Molecular Beam—Laser Spectroscopy Experiments and CCSD(T) Calculations
Authors: Řezáč Jan , Nachtigallová Dana , Mazzoni Federico , Pasquini Massimiliano , Pietraperzia Giangaetano , Becucci Maurizio , Müller‐Dethlefs Klaus , Hobza Pavel 
Published: March 2015

AbstractInvited for the cover of this issue is the group of Pavel Hobza at the Academy of Sciences of the Czech Republic. The image depicts the unravelling of new fundamental information at the intersection between laser experiments and quantum calculations. Read the full text of the article at 10.1002/chem.201406134.
Hypervalent Iodine(III)‐Mediated Benzannulation of Enamines with Alkynes: an Efficient Synthesis of Substituted Aminonaphthoic Acid Derivatives
Authors: Gao Peng , Fan Mingjin , Bai Zijing , Wei Yunyang 
Published: March 2015

Abstract An intermolecular two CC bond formation procedure for the synthesis of carbocycles mediated by hypervalent iodine(III) reagents was developed. This metal free protocol provided a new approach for the synthesis of useful substituted 1‐amino‐2‐naphthoic acid derivatives via benzannulation reactions. Various N‐unsubstituted and N‐alkyl substituted aromatic enamines with terminal alkynes and non‐terminal alkynes can be converted into corresponding 1‐amino‐2‐naphthoic acid derivatives under mild reaction conditions. When meta‐substituted phenyl enamines were employed in the reaction, two cyclization paths were detected in the reaction and ortho‐cyclization products were the only or major products. Good functional group tolerance, readily available material and high atom utilization efficiency make this method a potential procedure which may find broad application in organic synthesis.
Syntheses, Cytotoxicity and Properties of CO Releasing Molecules Containing Acetyl Salicylamide‐3‐pyridine
Authors: Liu Huapeng , Gong Yaguo , Zhang Taofeng , Li Na , Zhao Quanyi , Chen Yonglin , Liu Bin , Zheng Yawen 
Published: March 2015

AbstractA series of CO‐releasing molecules [M(CO)5L] (M=Cr, W, Mo, L=acetyl salicylamide 3‐pyridine, 1–3; L=N,N‐dimethyl‐4‐pyridine, 4–6; L=nicotinamide, 7–9; L=4‐CHO‐pyridine, 10–12) were synthesized. And in this paper, we have investigated mainly cytotoxicity and properties of the CO‐releasing molecules containing acetyl salicyamide‐3‐pyridine, namely complexes 1–3. The stability of complexes 1 and 2 was evaluated by means of UV‐Vis spectroscopy and 1H NMR spectra. The results indicate complexes 1 and 2 were stable in methanol and acidic aqueous solution, but unstable and decayed in basic media (pH 10.0). Among all the complexes, complex 2 was the slowest CO‐releaser, and its half‐life was 73.8 min. Complex 9 containing nicotinamide was the fastest CO‐releaser with half‐life only 6.5 min. In addition, cytotoxic effects of all the complexes on the proliferation of fibroblast line were assayed by MTT. Among all the complexes, the IC50 of complex 1 was 6 µmol/L, revealing complex 1 possessed stronger antiproliferative activity than the control. Analysis by Flow cytometry revealed that complex 1 arrested Hela cells in S phase while complexes 2 and 8 arrested in G2/M phase. Cell apoptosis caused by the complexes mainly occurred in "Late apoptosis".
Lanthanocene Diolate Complexes: Synthesis, Structures and Catalytic Property for ε‐Caprolactone Polymerization
Authors: Gu Zhanghai , Li Li , Bao Qianwen , Yuan Fugen 
Published: March 2015

AbstractReaction of LnCl3 first with three equivalent of C5H5Na in THF, then with one equivalent of N‐phenyldiethanolamine in THF‐DME afforded complexes of {[(C5H5)Ln((‐OCH2CH2)2N(C6H5)]4((4‐Cl)}[Na(DME)4] (Ln=Sm (1), Yb (2)), being characterized by infrared spectra, elemental analyses and X‐ray crystallography. They are ionic pair compounds. The anionic part is a cluster, which can be viewed as a cyclic tetramer with four (C5H5)Ln units bridged by four pairs of OR groups, forming a pinwheel structure. Both the complexes can catalyze the ring‐opening polymerization of ε‐caprolactone under mild conditions, and complex 1 is more active than complex 2. The polymerization accords with one order reaction kinetics for monomer concentration. The molecular weight increases with the yield increasing, and the molecular weight distribution is rather narrow (1.19<PDI<1.29).
Synthesis of (R)‐(−)‐Muscone from (R)‐5‐Bromo‐4‐methylpentanoate: A Chiron Approach
Authors: Shen Junwei , Shi Yong , Tian Weisheng 
Published: March 2015

AbstractA synthesis of (R)‐muscone (1), a valuable musk odorant, is presented. The stereogenic center of muscone was introduced from methyl (R)‐5‐bromo‐4‐methylpentanoate (5), a chiral pool molecule developed in our group, and the macrocyclic ring was prepared by ring‐closing metathesis (RCM) reaction.
Crystal Structure and Host‐Guest Binding Ability of Three Types of Pillar[5]arenes
Authors: Liu Luzhi , Duan Wengui , Kou Yuhui , Wang Lingyun , Meier Herbert , Cao Derong 
Published: March 2015

AbstractA systematic research of the structural characterization and the host‐guest binding abilities between three types of pillar[5]arenes 3–5 (3 for Structure Type I, 4 for Structure Type II and 5 for Structure Type III) is carried out by 1H NMR measurements and X‐ray study. The results show that the configurations or symmetry of their cavities not only have large difference in these three types of pillar[5]arenes, but also have more or less variations even in the same structure type or the same host locked different guests such as crystals of 3a–3b, 4a–4d. On the other hand, the complexation behavior of pillar[5]arenes with 1,4‐dibromobutane (DBB) is affected by the different symmetrical structure or substituents on the rings.
Synthesis of Copillar[5]arene by Co‐oligomerization of Different Monomers and Its Application to Supramolecular Polymer Gel
Authors: Li Hui , Zhu Yuanrong , Shi Bingbing , Wu Guiyuan , Zhang Youming , Lin Qi , Yao Hong , Wei Taibao 
Published: March 2015

AbstractA copillar[5]arene derivative with different repeating units was synthesized by co‐oligomerization of different alkyl ethers. Copillar[5]arene‐based supramolecular polymer gel was formed by a self‐inclusion complexing in acetonitrile. The supramolecular polymer gel was driven by the CH· π interactions, and presented two phases as time went on, and finally, constructed the supramolecular organic framework. Notably, the supramolecular polymer gel showed reversible gel‐sol phase transitions upon heating and cooling. Meanwhile, the transparent films formed by the supramloecular gel show the potential application in the field of anti‐acid rain materials.
Phosphorous‐Based Pillar[5]arenes for Uranyl Extraction
Authors: Bai Bing , Fang Yuyu , Gan Quan , Yang Yuanyou , Yuan Lihua , Feng Wen 
Published: March 2015

AbstractOne phosphine oxide‐based pillar[5]arene 1a and two novel phosphorous‐based pillar[5]arenas 1b and 1c were synthesized for use as extractants in solvent extraction of UO22+. The results from host‐guest interactions pertinent to the extracted complexes of 1a–1c revealed a significant difference in complexation capability between 1a and 1b (or 1c) by using 1H NMR, 31P NMR and FT‐IR techniques. The extraction of UO22+ in separate extraction system and in simulated nuclear industry effluent containing 12 competing ions demonstrated the superior efficiency and selectivity of 1a towards UO22+ over other cations in acidic feed. Log‐log plot analysis indicated the 1:1 stoichiometry (ligand/metal) for the extracted complex formed between the ligand and UO22+.
Large Deviations from a Stationary Measure for a Class of Dissipative PDEs with Random Kicks
Authors: Jakšić Vojkan , Nersesyan Vahagn , Pillet Claude‐Alain , Shirikyan Armen 
Published: March 2015

AbstractWe study a class of dissipative PDEs perturbed by a bounded random kick force. It is assumed that the random force is nondegenerate, so that the Markov process obtained by the restriction of solutions to integer times has a unique stationary measure. The main result of the paper is a large deviations principle for occupation measures of the Markov process in question. The proof is based on Kifer's large‐deviation criterion, a coupling argument for Markov processes, and an abstract result on large‐time asymptotic for generalized Markov semigroups.© 2015 Wiley Periodicals, Inc.