bluuebunny/crossref_metadata_2025_split huggingface dataset:
High Fidelity Simulation Effectiveness in Nursing Students’ Transfer of Learning
Authors: Kirkman Tera R. 
Published: July 2013

AbstractBackground: Members of nursing faculty are utilizing interactive teaching tools to improve nursing student’s clinical judgment; one method that has been found to be potentially effective is high fidelity simulation (HFS). The purpose of this time series design study was to determine whether undergraduate nursing students were able to transfer knowledge and skills learned from classroom lecture and a HFS clinical to the traditional clinical setting.Method: Students (n=42) were observed and rated on their ability to perform a respiratory assessment. The observations and ratings took place at the bedside, prior to a respiratory lecture, following the respiratory lecture, and following simulation clinical.Results: The findings indicated that there was a significant difference (p=0.000) in transfer of learning demonstrated over time. Conclusions: Transfer of learning was demonstrated and the use of HFS was found to be an effective learning and teaching method. Implications of results are discussed.
Solvent extraction of Zr and Hf from hydrochloric acid using tributylphosphate for the extraction of element 104, rutherfordium
Authors: Kasamatsu Y. , Kikutani Y. , Kino A. , Komori Y. , Yokokita T. , Yoshimura T. , Takahashi N. , Shinohara A. 
Published: July 2013

SummaryFor the solvent extraction experiment on element 104 (Rf), solvent extraction of Zr and Hf as its homologues was performed in tributylphosphate (TBP)/hydrochloric acid (HCl) system using the carrier-free radiotracers88Zr and175Hf. Time dependences of the distribution ratios of Zr and Hf were investigated using 6.1 and 10.0M HCl and 0.5 and 2.0M TBP benzene solutions. The distribution ratios in equilibrium were determined for these elements as a function of HCl concentrations in the range of 4.1-10.2M. We found that the neutral chloride complexes of Zr and Hf were formed and extracted into the organic phase within 20 min in HCl with a concentration higher than 6 M. From the results, we propose that solvent extraction of Rf from 4-8M HCl into 2.0M TBP benzene is suitable for investigating the chloride complexation properties of Rf. In addition, for the development of the rapid liquid-liquid extraction apparatus, three types of microchannel devices, namely, a micro reactor, capillary tube and micro-chemical chip, were tested as a mixing-solution part in the apparatus. The chemical reactions of Zr and Hf in the extraction were found to be fast only when using the microchemical chip, which is important for investigations with the 68-s261Rf.
New trends in nuclear data research for medical radionuclide production
Authors: Qaim S. M. 
Published: July 2013

SummaryNuclear reaction cross section data are of great significance in optimisation of production routes of radionuclides. This article deals with some newer aspects of data research related to production of both standard and novel radionuclides. The recent work to standardise the known data is discussed and new measurements with regard to further optimisation of production routes of some commonly used radionuclides are mentioned. Attempts to increase the specific activity of some reactor-produced radionuclides through the use of charged-particle induced reactions are outlined. The jeopardy in the supply of99mTcviaa fission-produced99Mo/99mTc generator is considered and its possible direct production at a cyclotron is briefly discussed. Regarding the novel radionuclides, development work is presently focussed on non-standard positron emitters for diagnosis and on low-range highly ionising radiation emitters for internal radiotherapy. Recent nuclear reaction cross section measurements related to the production of the two types of radionuclides are briefly reviewed and some anticipated trends in nuclear data research are considered.
Sequence Diversity in Coding Regions of Candidate Genes in the Glycoalkaloid Biosynthetic Pathway of Wild Potato Species
Authors: Manrique-Carpintero Norma C , Tokuhisa James G , Ginzberg Idit , Holliday Jason A , Veilleux Richard E 
Published: July 2013

Abstract
Natural variation in five candidate genes of the steroidal glycoalkaloid (SGA) metabolic pathway and whole-genome single nucleotide polymorphism (SNP) genotyping were studied in six wild [Solanum chacoense (chc 80-1), S. commersonii, S. demissum, S. sparsipilum, S. spegazzinii, S. stoloniferum] and cultivated S. tuberosum Group Phureja (phu DH) potato species with contrasting levels of SGAs. Amplicons were sequenced for five candidate genes: 3-hydroxy-3-methylglutaryl coenzyme A reductase 1 and 2 (HMG1, HMG2) and 2.3-squalene epoxidase (SQE) of primary metabolism, and solanidine galactosyltransferase (SGT1), and glucosyltransferase (SGT2) of secondary metabolism. SNPs (n = 337) producing 354 variations were detected within 3.7 kb of sequenced DNA. More polymorphisms were found in introns than exons and in genes of secondary compared to primary metabolism. Although no significant deviation from neutrality was found, dN/dS ratios &lt; 1 and negative values of Tajima’s D test suggested purifying selection and genetic hitchhiking in the gene fragments. In addition, patterns of dN/dS ratios across the SGA pathway suggested constraint by natural selection. Comparison of nucleotide diversity estimates and dN/dS ratios showed stronger selective constraints for genes of primary rather than secondary metabolism. SNPs (n = 24) with an exclusive genotype for either phu DH (low SGA) or chc 80-1 (high SGA) were identified for HMG2, SQE, SGT1 and SGT2. The SolCAP 8303 Illumina Potato SNP chip genotyping revealed eight informative SNPs on six pseudochromosomes, with homozygous and heterozygous genotypes that discriminated high, intermediate and low levels of SGA accumulation. These results can be used to evaluate SGA accumulation in segregating or association mapping populations.
Mitochondrial DNA with a Large-Scale Deletion Causes Two Distinct Mitochondrial Disease Phenotypes in Mice
Authors: Katada Shun , Mito Takayuki , Ogasawara Emi , Hayashi Jun-Ichi , Nakada Kazuto 
Published: July 2013

Abstract
Studies in patients have suggested that the clinical phenotypes of some mitochondrial diseases might transit from one disease to another (e.g., Pearson syndrome [PS] to Kearns-Sayre syndrome) in single individuals carrying mitochondrial (mt) DNA with a common deletion (∆mtDNA), but there is no direct experimental evidence for this. To determine whether ∆mtDNA has the pathologic potential to induce multiple mitochondrial disease phenotypes, we used trans-mitochondrial mice with a heteroplasmic state of wild-type mtDNA and ∆mtDNA (mito-mice∆). Late-stage embryos carrying ≥50% ∆mtDNA showed abnormal hematopoiesis and iron metabolism in livers that were partly similar to PS (PS-like phenotypes), although they did not express sideroblastic anemia that is a typical symptom of PS. More than half of the neonates with PS-like phenotypes died by 1 month after birth, whereas the rest showed a decrease of ∆mtDNA load in the affected tissues, peripheral blood and liver, and they recovered from PS-like phenotypes. The proportion of ∆mtDNA in various tissues of the surviving mito-mice∆ increased with time, and Kearns-Sayre syndrome−like phenotypes were expressed when the proportion of ∆mtDNA in various tissues reached &gt;70–80%. Our model mouse study clearly showed that a single ∆mtDNA was responsible for at least two distinct disease phenotypes at different ages and suggested that the level and dynamics of ∆mtDNA load in affected tissues would be important for the onset and transition of mitochondrial disease phenotypes in mice.
Efficacy of Preprocedural Mouth Rinsing in Reducing Aerosol Contamination Produced by Ultrasonic Scaler: A Pilot Study
Authors: Gupta Gunjan , Mitra Dipika , Ashok K.P. , Gupta Arun , Soni Sweta , Ahmed Sameer , Arya Ashtha 
Published: July 2013

Background: The aerosol generated by an ultrasonic scaler contains microorganisms that can penetrate into the body through the respiratory system of dental surgeons and patients. The aim of this pilot study is to evaluate and compare the efficacy of commercially available preprocedural mouthrinses containing 0.2% chlorhexidine gluconate, an herbal mouthwash, and water in reducing the levels of viable bacteria in aerosols.Methods: This single‐center, double‐masked, placebo‐controlled, randomized, three‐group parallel design was conducted over a period of 45 days. Twenty‐four patients with chronic periodontitis were divided randomly into three groups (A, B, and C) of eight patients each to receive 0.2% chlorhexidine gluconate, herbal mouthwash, and water, respectively, as a preprocedural rinse. The aerosol produced by the ultrasonic unit was collected at patient's chest area, doctor's chest area, and assistant's chest area on blood agar plates in all three groups. The blood agar plates were incubated at 37°C for 48 hours, and the total number of colony‐forming units (CFUs) was counted and statistically analyzed.Results: The results showed that CFUs in groups A and B were significantly reduced compared with group C, P <0.001 (analysis of variance). Also, CFUs in group A were significantly reduced compared with group B, P <0.05 (independent t‐test). The numbers of CFUs were highest at the patient's chest area and lowest at the assistant's chest area.Conclusion: This study suggests that a routine preprocedural mouthrinse could eliminate the majority of bacterial aerosols generated by the use of an ultrasonic unit, and that 0.2% chlorhexidine gluconate is more effective than herbal mouthwash.
Cadmium and hypertension in exposed workers: A meta-analysis
Authors: Caciari Tiziana , Sancini Angela , Fioravanti Mario , Capozzella Assunta , Casale Teodorico , Montuori Lucio , Fiaschetti Maria , Schifano Maria , Andreozzi Giorgia , Nardone Nadia , Tomei Gianfranco , Ciarrocca Manuela , Rosati Maria , Tomei Francesco 
Published: July 2013

Abstract
Isolation and characterization of microsatellite markers in Beilschmiedia roxburghiana (Lauraceae)
Authors: Liu Lu , Wang Zheng‐Feng , Li Qiao‐Ming , Ye Wan‐Hui , Cao Hong‐Lin , Wang Zhang‐Ming 
Published: July 2013

• Premise of the study: Although there are as many as 250 species in the genus Beilschmiedia, their genetic diversity has been poorly investigated. Our objective was to develop microsatellite markers for B. roxburghiana to study its genetic diversity for the sustainable management of this species.• Methods and Results: Using the microsatellite‐enriched library and PCR‐based screening method, 22 microsatellite markers were developed and 10 showed high polymorphism in a population. The number of alleles per locus for these 10 microsatellites ranged from five to 19. The observed and expected heterozygosities ranged from 0.298 to 1.000 and from 0.314 to 0.878, respectively.• Conclusions: Our results from the 10 highly polymorphic microsatellites indicate that the principal reproductive mode of B. roxburghiana is clonal in the studied population. These microsatellites will facilitate further studies on genetic diversity and structure in B. roxburghiana.
Targeting of putative fimbrial gene for detection of S. Typhi in typhoid fever and chronic typhoid carriers by nested PCR
Authors: Pratap Chandra Bhan , Kumar Gopal , Patel Saurabh Kumar , Verma Ajay Kumar , Shukla Vijay K , Kumar Kailash , Nath Gopal 
Published: July 2013

Introduction: It is important to identify Salmonella Typhi infection quickly to treat acute fever patients and to prevent transmission by chronic typhoid carriers; therefore, a very specific and sensitive diagnostic technique is highly desirable, especially in endemic areas. The objective of this study was to develop a PCR protocol targeting the putative fimbrial staA gene of S. Typhi. This is a preferred target gene that is specifically amplified in the S. Typhi serotype compared to the commonly targeted fliC gene which may also be amplified from the non-typhoidal Salmonella Munchen serotype. Methodology: A new nested PCR primer methodology was designed to target the staA gene, which is a member of the fimbrial gene family specific to Salmonella Typhi only. Results: The primers were found to be very specific as the desired amplicon (377 bp) could be generated exclusively from S. Typhi strains including the reference strain (MTCC 3216) and 78 clinical isolates . Restriction digestion with HinfI confirmed the identity of the amplified DNA fragment in clinical specimens of S. Typhi origin. Furthermore, these primers were able to detect a minimum of three colony forming units per ml (1fg) in spiked blood samples. The detection sensitivity of the described primers is comparable to that of previously published primers targeting fliC gene sequences. Conclusions: This study indicates that the primers targeting the putative fimbrial staA gene are very specific to the Typhi serotype and may be a better alternative to fliC targeted amplification based diagnosis.
A Decoding Strategy for Amplitude-Discriminating Type Twin-Channel Brushless Resolver Decoding System Based on AD2S80A Chip
Authors: Liu Guang Qi , Zhou Wei Jia 
Published: July 2013

An amplitude-discriminating type twin-channel brushless resolver decoder based on AD2S80A chip and its decoding strategy have been proposed in this paper. The decoder uses two AD2S80A chips as resolver-to-digital converter (RDC). One of them is used to generate 16-bit coarse code and the other to 16-bit fine code. Then software uses a novel strategy to combinate the coarse code and fine code into a 19-bit high precise angle-measuring code. Finally, an experiment has verified the strategy which is practical for high precise angle position sensing. // <![CDATA[
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National Athletic Trainers' Association Position Statement: Conservative Management and Prevention of Ankle Sprains in Athletes
Authors: Kaminski Thomas W. , Hertel Jay , Amendola Ned , Docherty Carrie L. , Dolan Michael G. , Hopkins J. Ty , Nussbaum Eric , Poppy Wendy , Richie Doug 
Published: July 2013

Objective:To present recommendations for athletic trainers and other allied health care professionals in the conservative management and prevention of ankle sprains in athletes.Background:Because ankle sprains are a common and often disabling injury in athletes, athletic trainers and other sports health care professionals must be able to implement the most current and evidence-supported treatment strategies to ensure safe and rapid return to play. Equally important is initiating preventive measures to mitigate both first-time sprains and the chance of reinjury. Therefore, considerations for appropriate preventive measures (including taping and bracing), initial assessment, both short- and long-term management strategies, return-to-play guidelines, and recommendations for syndesmotic ankle sprains and chronic ankle instability are presented.Recommendations:The recommendations included in this position statement are intended to provide athletic trainers and other sports health care professionals with guidelines and criteria to deliver the best health care possible for the prevention and management of ankle sprains. An endorsement as to best practice is made whenever evidence supporting the recommendation is available.
Le Fardeau de la légèreté : une étude de Kimchi d’Ook Chung
Authors: Yang Ziyan 
Published: July 2013

Depuis la naissance de la littérature du Québec qui vise la construction de l’identité québécoise, le rapport entre la saisie du Soi et la perception de l’Autre constitue un noyau dur du discours littéraire. Aujourd’hui, avec l’émergence des écrivains migrants ou néo-québécois (différenciés des écrivains québécois « de souche »), le Soi et l’Autre se rapprochent à tel point que leurs frontières se dissolvent dans cette écriture dite « migrante ». Cet article s’intéresse à la représentation de l’identité dans le premier roman Kimchi par Ook Chung, un écrivain québécois d’origine asiatique. En nous appuyant sur les recherches de Charles Taylor et de Paul Ricoeur portant sur la notion de l’identité, nous réfléchissons d’abord sur la dialectique entre le Soi et l’Autre dans la quête identitaire du protagoniste. Ensuite, nous analysons le langage de Chung à la croisée des cultures selon le concept de l’« hybridité » proposé par Homi Bhabha. Finalement, nous portons notre attention au rôle de l’art et de l’écriture dans l’élaboration identitaire chez Chung.
Keep calm and reboot – how cells restart transcription after DNA damage and DNA repair
Authors: Donnio Lise‐Marie , Giglia‐Mari Giuseppina 
Published: July 2024

The effects of genotoxic agents on DNA and the processes involved in their removal have been thoroughly studied; however, very little is known about the mechanisms governing the reinstatement of cellular activities after DNA repair, despite restoration of the damage‐induced block of transcription being essential for cell survival. In addition to impeding transcription, DNA lesions have the potential to disrupt the precise positioning of chromatin domains within the nucleus and alter the meticulously organized architecture of the nucleolus. Alongside the necessity of resuming transcription mediated by RNA polymerase 1 and 2 transcription, it is crucial to restore the structure of the nucleolus to facilitate optimal ribosome biogenesis and ensure efficient and error‐free translation. Here, we examine the current understanding of how transcriptional activity from RNA polymerase 2 is reinstated following DNA repair completion and explore the mechanisms involved in reassembling the nucleolus to safeguard the correct progression of cellular functions. Given the lack of information on this vital function, this Review seeks to inspire researchers to explore deeper into this specific subject and offers essential suggestions on how to investigate this complex and nearly unexplored process further.
An Advanced Anode Composed of Layered Single‐Crystal Metal–Organic Framework Material for Ultra‐Long Cycle‐Life Sodium‐Ion Batteries
Authors: Shuang Wei , Wang Ya , Wu Yujun , Ma Nana , Chen Fuyou , Wang Xin , Yan Wei , Bai Zhengyu , Yang Lin , Zhang Jiujun 
Published: July 2024

AbstractDeveloping advanced anode materials for sodium‐ion batteries (SIBs) is a frontier and hotspot research for clean and sustainable electricity energy storage and conversion. However, it is still challenging to obtain anode materials with high stability, multiple active sites, and high conductivity. In this paper, an advanced metal–organic framework (MOF)‐based anode material (Co‐HITP), which integrates multiple advantages into one, is successfully synthesized through a sodiation‐stimulated in situ reconstruction. The Co‐HITP possesses a stable single‐crystal structure, expanded spacing layers, abundant sites, and good conductivity, and exhibits superior properties with ultra‐long cycling stability (ultralow decay rate ≈0.001% per cycle after 15 000 cycles at 8 A g−1), high reversible capacity (450.1 mA h g−1 at 0.2 A g−1), and excellent rate performance. Both experimental results and theoretical calculation reveal that the anode remains a stable structure after long cycling, attributed to the single‐crystal structure with d‐π hybridization and π–π interaction, and the minimum structural unit stores 6Na+ ions of C═N sites and 8Na+ ions of aromatic rings. This discovery is significant for developing advanced anode materials with integrated advantages for SIBs.
PbSe Quantum Dot Superlattice Thin Films for Thermoelectric Applications
Authors: Sousa Viviana , Goto Masahiro , Claro Marcel S. , Pyrlin Sergey , Marques Luis , Modin Evgeny B. , Lebedev Oleg I. , Alizadeh Siavash M. , Freitas Cátia , Vieira Eliana M. F. , Kovnir Kirill , Alpuim Pedro , Mori Takao , Kolen'ko Yury V. 
Published: July 2024

AbstractAn unusual self‐assembly pattern is observed for highly ordered 1500‐nm‐thick films of monodisperse 13‐nm‐sized colloidal PbSe quantum dots, originating from their faceted truncated cube‐like shape. Specifically, self‐assembled PbSe dots exhibited attachment to the substrate by <001> planes followed by an interconnection through the {001} facets in plan‐view and {110}/{111} facets in cross‐sectional‐view, thus forming a cubic superlattice. The thermoelectric properties of the PbSe superlattice thin films are investigated by means of frequency domain thermoreflectance, scanning thermal probe microscopy, and four‐probe measurements, and augmented by computational efforts. Thermal conductivity of the superlattice films is measured as low as 0.7 W m−1 K−1 at room temperature due to the developed nanostructure. The low values of electrical conductivity are attributed to the presence of insulating oleate capping ligands at the dots’ surface and the small contact area between the PbSe dots within the superlattice. Experimental efforts aiming at the removal of the oleate ligands are conducted by annealing or molten‐salt treatment, and in the latter case, yielded a promising improvement by two orders of magnitude in thermoelectric performance. The result indicates that the straightforward molten‐salt treatment is an interesting approach to derive thermoelectric dot superlattice thin films over a centimeter‐sized area.