bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dynamics of Some Medical and Demographic Indicators in St. Petersburg During the Period from 2018 to 2023
Authors: Simakhodsky Anatoly S. , Sevostyanova Ludmila D. , Lukashоva Yulia V. , Petrova Natalya V. , Simakhodsky Oleg A. 
Published: July 2024

Background. There have been negative trends in the birth rate and population growth decline in recent years. Forecasts from demographers are also not so encouraging as the next generation of childbearing age is one from the end of the last century which is characterized by low birth rate. Population mortality exceeded the birth rate during the years of challenging and questionable economic reforms. Moreover, there was a high level of chronic morbidity in child population, and physical development had the trend to retardation. Meanwhile under these circumstances, the President of Russian Federation and the Government adopted regulatory documents (decrees, dedicated programs) that determined the directions of state social policy on improving the situation with children in Russian Federation until 2000.Objective. The aim of the study is to evaluate the dynamics of several medical and social indicators of 2018–2023 characterizing demographic trends direction, with proposals on improving medical care in the maternal and child health care system.Methods. The study has covered reporting form No. 19 of Russian Federal State Statistics Service (Rosstat) for children’s outpatient clinics, form No. 14 for children’s hospitals, form No. 030/у “Check-list of dispensary observation”. The study has used the materials of the Presidential Coordination board meeting from November 15, 2016. Statistical data was obtained from the “Office of the Federal State Statistics Service for St. Petersburg and the Leningrad Region” (Petrostat) and the Center for Analysis and Forecast of Mother and Child Health at Health Committee of St. Petersburg, Medical Information and Analytical Center (“Major results in the field of health care in St. Petersburg”, 2019, 2020, 2021, 2022). Statistical processing was carried out via variational statistics methods (Pearson’s criterion, Fisher’s angular transformation criterion) and data from the automated system of prophylactic medical examination, registration certificate FSR No. 2009/05279, corresponding to the order of the Ministry of Health of Russian Federation No. 514н dated August 10, 2017.Results. The analysis of study results confirms the negative demographic patterns in St. Petersburg like the all-Russian. Increase assisted reproductive technologies was noted alongside with birth rate decrease. There are still high rates of stillbirth and perinatal mortality, as well as increased infant mortality rate. The correlation of depopulation processes with children’s health worsening and increasing disability is emphasized.Conclusion. The problems raised in this paper do not have an straightforward solution and require multimodal approach.
Niemann-Pick Disease, Type A: Clinical Case of 5 Months Old Patient
Authors: Zhurkova Nataliya V. , Vashakmadze Nato V. , Surkov Andrey N. , Turti Tatiana V. , Bogdanova Kristina V. , Kotalevskaya Yuliya Yu. , Zakharova Ekaterina Yu. , Namazova-Baranova Leyla S. 
Published: July 2024

Background. Niemann-Pick disease, type A is a rare hereditary disease from the group of lysosomal storage diseases, it is characterized by early onset and progressive course. Description of this disease’s clinical cases is crucial for early diagnosis and adequate management due to its rarity, rapid progression, and the development of new pathogenetic therapy methods.Clinical case description. The disease manifested on the second month of the patient’s life with poor weight gain, frequent pneumonia, hepatosplenomegaly, diffuse muscular hypotonia, delayed motor development, and progressive neurological symptoms. Laboratory testing has revealed significant decrease in sphingomyelinase activity in blood. The heterozygous deletion c.996del in exon 2 of the SMPD1 gene has been revealed via direct automatic sequencing; it leads to frameshifting p.F333Sfs*52 (inherited from mother). Moreover, the previously described pathogenic nucleotide variant c.1252C>T (heterozygous) has been revealed in exon 3 of the SMPD1 gene; it leads to translation arrest p.Arg418* (inherited from father). Cherry-red spots were diagnosed at fundospcopy. The diagnosis of Niemann-Pick disease, type А was established according to clinical signs and molecular genetic testing results.Conclusion. The detection of physical and motor development delay, diffuse muscular hypotonia, hepatosplenomegaly, cherry-red spots at ophthalmological examination, lung involvement, recurrent pneumonia, and progressive neurological symptoms in a child during the first months of life indicates that this patient has Niemann-Pick disease, type А. Early molecular genetic testing is crucial for timely choosing the management approach and further genetic counselling of the family.
Chitosan-based polyelectrolyte complex in combination with allotropic forms of carbon as a basis of thin-film organic electronics
Authors: Zilberg Rufina , Salikhov Renat , Mullagaliev Ilnur , Teres Yulia , Bulysheva Elena , Salikhov Timur , Ostaltsova Anastasia , Vakulin Ivan 
Published: July 2024

Using atomic force microscopy, scanning electron microscopy, cyclic voltammetry and electrochemical impedance spectroscopy, the morphology and mobility of charge carriers in composite films with a thickness of no more than 500 nm obtained on the basis of a polyelectrolyte complex of chitosan and chitosan succinamide with addition of particles of carbon materials were studied and estimated. The following carbon materials were used: single-walled carbon nanotubes, graphene oxide, and carbon-containing sorbents with different specific surfaces (Carboblack C and Carbopack). Moreover, the studied materials in the form of films were used as a transport layer in the structure of field-effect transistors. The output and transfer characteristics of the transistors obtained were measured. According to the measurement results, the mobility of charge carriers, µ, ranges from 0.341 to 1.123 cm2 V–1·s–1, depending on the type of carbon material added. The best result was demonstrated by films based on a composite containing simultaneously single-walled carbon nanotubes and graphene oxide (μ = 10.972 cm2 V–1·s–1).
Effects of Zibotentan Alone and in Combination with Dapagliflozin on Fluid Retention in Patients with CKD
Authors: Smeijer J. David , Wasehuus Victor S. , Dhaun Neeraj , Górriz José Luis , Soler Maria José , Åstrand Magnus , Mercier Anne-Kristina , Greasley Peter J. , Ambery Phil , Heerspink Hiddo J.L. 
Published: July 2024

Key Points

Increasing doses of the endothelin receptor antagonist zibotentan and lower eGFR were associated with a higher risk of fluid retention.The higher risk of fluid retention could be attenuated by the combination of zibotentan with the sodium-glucose cotransporter 2 inhibitor dapagliflozin.

Background
Endothelin receptor antagonists (ERAs) reduce albuminuria but are limited by fluid retention risk, particularly in patients with CKD. Combining ERAs with sodium-glucose cotransporter 2 (SGLT2) inhibitors, which have diuretic effects, offers a promising strategy to mitigate fluid retention. In this post hoc analysis of the Zibotentan and Dapagliflozin for the Treatment of CKD (ZENITH-CKD) trial, we assessed fluid dynamics in patients with CKD treated with the ERA zibotentan alone and in combination with the SGLT2 inhibitor dapagliflozin.

Methods
In the ZENITH-CKD trial, 508 patients with CKD (eGFR ≥20 ml/min per 1.73 m2 and a urinary albumin-creatinine ratio of 150–5000 mg/g) were randomized to treatment with placebo, dapagliflozin 10 mg plus placebo, zibotentan (0.25, 1.5, or 5 mg) plus dapagliflozin 10 mg, and zibotentan 5 mg plus placebo. We evaluated correlations between changes in fluid retention markers and bioimpedance-measured extracellular fluid in response to zibotentan treatment. We used Cox proportional hazards regression to assess the association between zibotentan/dapagliflozin treatment, baseline characteristics, and fluid retention and the relationship between zibotentan plasma exposure and fluid retention.

Results
After 3 weeks of treatment with zibotentan 0.25, 1.5, or 5 mg plus dapagliflozin 10 mg, changes in body weight (β=0.36 [95% confidence interval (CI), 0.26 to 0.45]) per kg, B-type natriuretic peptide (β=0.38 [95% CI, 0.22 to 0.54]) per doubling, and hemoglobin (β=−0.29 [95% CI, −0.48 to −0.10]) per g/dl were independently associated with changes in extracellular fluid. Higher doses of zibotentan were associated with significantly higher risk of fluid retention compared with dapagliflozin alone (zibotentan 5 mg hazard ratio (HR) 8.50 [95% CI, 3.40 to 21.30]). The HR attenuated when zibotentan was combined with dapagliflozin (zibotentan/dapagliflozin 5/10 mg HR 3.09 [95% CI, 1.08 to 8.80], zibotentan/dapagliflozin 1.5/10 mg 2.70 [95% CI, 1.44 to 5.07], and zibotentan/dapagliflozin 0.25/10 mg HR 1.21 [95% CI, 0.50 to 2.91]). The risk of fluid retention was higher with higher zibotentan exposure and lower eGFR.

Conclusions
High doses of zibotentan were associated with a higher risk of fluid retention, which was attenuated with lower doses and the addition of dapagliflozin.

Clinical Trial registry name and registration number:
ZENITH-CKD Trial, NCT04724837.
Communication Skill Training for Female Online Ojek Drivers
Authors: Agustina Tri Siwi , Khant Thant Thet Oo , Meilinawati Neni 
Published: July 2024

Doing online motorcycle taxi work is required to not only be able to drive motorized vehicles, but also requires various skills and techniques to become a successful online motorcycle taxi driver, including communication skills. Communication Skill Training is aimed at 26 female online ojek drivers in the city of Surabaya. The method of implementing community service activities is experiential learning in the form of practice and also interspersed with lectures. The results of the observation occurred a change in the attitude of the participants in communicating, for example, being more confident and wiser in word selection. In addition, the experiential learning method has proven effective for changing attitudes and improving partner communication skills.
The Genesis of The Language of Arab Youth in the Modern Era/ نشأة لغة الشباب العربي في العصر الحديث
Authors: Hasan Hamilah , Afida Febrian Nafisah Nurul 
Published: July 2024

The purpose of writing this journal is to find out the language of young people in modern times, which is influenced by the Arabic language Fusha and Amiyah which are used as the language of the native Arabic. The language user is also influenced by Fusha and Amiyah language differences. In this journal the author also describes the language of Egyptian youth in the early twenty-first century, then the language of women in the 11th century which is also considered to affect the language of young people in modern times. The method used by the authors in this journal is to use a library analysis approach that is describing using theories supported by valid and up-to-date literature. The results of this journal writing are that the components contained in the contents of this journal are all continuous in influencing the language of young people in modern times. كما عرفنا من أهداف كتابة هذا البحث يعني لحث المفارقة في اللغة المتقدمين و اللغة الشباب اليوم نشأتها وتنميتها في العالم مع مرور الحضارة. كما رأينا لاحقا أنّ نشأة الفصحى في قريش واعتمادها على الكثير من خصائص شيئ مختلفة فيه. والفصحى أيضا، هي ظرف لم يتوفر لآية لغة من اللغات العالم أنها ارتبطت القرآن الكريم منذ أربعة عشر قرنا. فنشأة حضارة الشباب تأثرت إلى نشأن لغتهم عمية كانت أو فصحة في المستقبل مع أنهما العربية فشتان بينهما. في هذا الحين بين الباحث أيضا لغة شباب المصريين في بدء أول القرن الحادي والعشرين ثم لغة المرأة التي تأثرت تأثيرا عظيما أيضا نحو شباب اليوم في القرن الحادي عشر. وأما مدخل البحث الذي استخدمه الباحث يعني بحث مكتبي لتحليل مشكلات البحث بنظرية الموافقة مؤلفة كانت وصالحة. وأما الحاصلة من كتابة هذا البحث اجماليا هي مكونات التي اشتملت في هذا البحث كلها اتصاليا بمؤثرة لغة شباب اليوم في عصرنا هذا.
Towards the Use of Modern and Basic Skills in Teaching Arabic to Non-Native Speakers at The Junior Secondary Schools’ Level in Nigeria/ نحو استخدام المهارات الأساسية الحديثة في تعليم اللغة العربية للناطقين بغيرها في المرحلة المتوسطة في نيجيريا
Authors: Garba Ahmad 
Published: July 2024

Language is one of the features that human being is differed from other creatures, and it constitutes a great cognitive manifestation and mental characteristics. On this basis, the process of teaching languages in general requires necessary skills and techniques, so also the teaching of Arabic to non-native speakers requires basic skills and strategies. The main objective of this paper is to highlight the needs and justifications of using modern approaches towards teaching Arabic language to non-native speakers in junior secondary schools in Nigeria. The teaching process does not dispense with the necessary basic skills, which are the basis on which teachers build their activities in the classroom to send information and ideas to the minds of learners, and these skills did not stop inside the classroom only, but even outside it. These basic skills include: the skill of set induction, skill of classroom management, skill of asking questions, skill of reinforcement, skill of using chalkboard, and the skill of using various teaching method. إن اللغة من المميزات التي انفرد الإنسان بها عن غيره من سائر المخلوقات, وهي تشكل أعظم ما تتجلى فيه مميزاته العقلية.وهي من الحاجات الأساسية اللإنسان, بها يقوم بينه وبين غيره علاقة تبادلية وثيقة. وعلى هذا الأساس تحتاج عملية التعليم اللغات بوجه عام إلى مهارات وتقنيات الازمة كما تتطلب تعليم اللغة العربية للناطقين بغيرها مهارات واستراتيجيات أساسية بوجه خاص. هدفت هذه الورقة إلفاء الضوء على مبررات استخدام المهارات الأساسية في تعليم اللغة العربية للناطقين بغيرها نحو الطلبة المرحلة المتوسطة في نيجيريا.لا تستغني عملية التدريس عن المهارات الأساسية الازمة، وهي الأساس التي يبني عليها المدرسين عملياتهم داخل الفصل لإرسال المعلومات والأفكار إلى أذهان المتعلمين، وهذه المهارات لم تقف داخل الغرفة الصف فحسب،بل حتى خارجها. وتحتوي هذه الورقة الي مقدمة ومنهجية البحث ومفهوم التدريس وأهمية المهارات التدريس ثم البيان حول بعض المهارات التدريس الأساسية في عملية التدريس ثم نتائج البحث والمقترحات والخاتمة والمراجع.
Trend of Arabic Language Use in Indonesian Brands: Onomastic Studies on Arabic Shop Names in Tulungagung
Authors: Rasyid Mufti 
Published: July 2024

The trend of naming brands in Indonesia is always changing from time to time. In the last decade, there has been a notable change from western language (English or Latin) to Arabic language such as Wardah, Safi, and Zoya. Not only national class brands, local shop names are also increasingly using Arabic. Nowadays, we often see Arabic products and shops in the market such as Al-Azhar, Yasmin, and El-Faza. This study aims to reveal the phenomenon and meanings behind the use of Arabic in naming local brands in Indonesia, especially in Tulungagung. The research is conducted using onomastic studies. Onomastics is one discipline of socio linguistics that studies the etymology, history, and use of names. Using qualitative descriptive method, this study analyzes the form, reference meaning, and function of the use of Arabic language in shop names in Tulungagung. The researcher uses observation, documentation, and interviews to collect the data. The results of this study reveal that the naming system for shops in Tulungagung is conducted using particular techniques like using single words in Arabic or combination of Arabic and English or Indonesian. Meanwhile the origin of the names could be traced to personal (self and family) names, geographic names, or Islamic terms. The purposes of Arabic naming consist of showing the identity of the owner, matching the type of products and service and the emergence of halal life style. It is in line with the rise of Islamic spirit which is related with the role of Arabic as a symbol of cultural identity.
Knowledge and practices regrading food of female domestic workers (FDW/ Housemaids) in selected areas of Pune city
Authors: Jamdade Yuva Nilesh , Patankar Preeti V 
Published: July 2024

To study the knowledge and practices regarding food of female domestic workers (housemaids) in selected areas of Pune city. A non-probability convivence sampling technique was used to interview 150 housemaids in selected areas of Pune city. The study was conducted from March 2023 to April 2023. The data was coded in MS Excel and was analyzed by using SPSS software version 20. The statistical significance was declared at p value &#60; 0.05. A total of 150 participants were interviewed & the responses were recorded, analyzed & results were observed, the significant correlation between Knowledge and Practices is seen at a 0.001 level of significance, which can be discussed as, the knowledge of the housemaids is high in (70.6 %) of and the housemaids practice the knowledge in their homes as well as work places with a moderate (58%) and high (41.4%) percentages. Practices regarding eating, meal patterns, cooking, dietary habits and food and personal hygiene are also observed. A significant correlation was found between knowledge and practices regarding food amongst female domestic workers (housemaids) in Pune city.
To the memory of the geographer-palynologist Evgenia Sergeevna Malyasova (to her 100th birthday)*
Authors: Silin V. 
Published: July 2024

The article is dedicated to the 100th anniversary of the highly qualified palynologist, teacher of many geographers graduated from the Leningrad State University (Department of Geography) Evgenia Sergeevna Malyasova (1923–2020). E. S. Malyasova was a student of I. M. Pokrovskaya, the founder of the Palynological Laboratory at the Department of Geography at the Leningrad State University. She headed the Palynological Laboratory for more than 20 years, gave lectures at the Department of Geomorphology at the Leningrad State University, conducted active scientific research works on the palynology of the Arctic territories and sediments of the White and Barents Seas. The paper contains details of her life and scientific activities.
Syndrome frailty and his features in Parkinson’s disease
Authors: Guseva O. V. 
Published: July 2024

Syndrome frailty is widespread all over the world and its appearance is associated with an increase in life expectancy. The lecture shows the multifactorial nature of the syndrome: changes in physical health, social and psychological factors, gender characteristics and age. The classic diagnosis of the syndrome consists in assessing physical weakness according to the Fried phenotype. The modern view of the problem complements the diagnosis with indices of weakness to characterize the multifactorial development and the use of digital wearable technologies for long-term monitoring of the patient’s functional parameters.The lecture provides a detailed justification of the effect of comorbidity on the development of syndrome frailty. The syndrome frailty is difficult diagnosed in Parkinson’s disease, because it has high prevalence in these. Studies of syndrome frailty in Parkinson’s disease are few, probably due to the similarity of the symptoms of the disease and the syndrome. The lecture identifies the possible risks of syndrome frailty in Parkinson’s disease: the influence of various forms of Parkinson’s disease, gender, cognitive and functional disorders, polypharmacy, levodopa doses. The role of multidisciplinary rehabilitation’s team and independent physical activity in the combination of Parkinson’s disease and syndrome frailty is shown.
The state and vascularization of the bone marrow transplanted in the diffusion chamber to the rat neurovascular bundle
Authors: Dvornichenko M. V. , Marzol E. A. , Zinovyev E. А. , Mitryaikin N. S. , Khlusov I. A. 
Published: July 2024

Background. The diffusion chamber method helps solve the problem of delivering a biomaterial with minimal losses, while creating an isolated environment in the recipient’s body. The issue of vascularization of diffusion chambers to preserve the functional capacity of the biomaterial remains relevant. A bioengineered diffusion chamber model, together with the vascular adventitia, promotes vascularization of the biomaterial placed in the chamber. The aim of the study was to assess the state of the bone marrow placed in the diffusion chamber and transplanted to the femoral neurovascular bundle of a rat. Materials and methods. The experimental part of the study was carried out on mature male Wistar rats. The animals were divided into two groups. Group 1 was experimental (n = 4), in which a polycaprolactone diffusion chamber filled with bone marrow was implanted in the femoral neurovascular bundle. Group 2 was control (n = 3), in which the diffusion chamber without bone marrow was implanted in a similar bundle. Results. The histologic examination of the structure of the compact capsule in the bioengineered model in the experimental group revealed areas of woven bone tissue in 25% of the rats. An increase in the vascularization coefficient by 96% and a rise in the Kernohan index by 7% in the experimental group compared to the control group indicated that sufficient conditions were formed to develop the microvasculature while maintaining the bone marrow differentiation path. Conclusion. The reliability of these results is confirmed by immunohistochemical markers of vascularization VEGF and CD34.
Deep Learning–Assisted Parameter Monitoring and Optimization in Rotary-Percussive Drilling
Authors: Sun Wucheng , Tao Yakun , Wang Zhiming , Tan Songcheng , Duan Longchen , Fang Xiaohong 
Published: July 2024

Summary
As an efficient method for hard rock fracturing, rotary-percussive drilling has been widely used in various scenarios, especially deep drilling. Drilling parameter monitoring and control are necessary to ensure stable and efficient underground drilling processes. However, this may be more difficult in deep, harsh conditions.
In this paper, our goal is to establish models based on deep learning for drilling parameter monitoring and optimization. Combining impregnated diamond bits and granite rock samples, we conducted rotary-percussive rock drilling experiments using a rock drilling test rig. Real-time acoustic signals during rotary-percussive drilling were recorded, segmented, and transformed as spectra, which made up a drilling acoustic signal data set. Drilling parameters, including rotational speed (revolutions per minute, RPM), pump flow rate, pump pressure, weight on bit (WOB), torque, and rate of penetration (ROP), were logged in the meantime. Given the acoustic signal as input, we built 1D convolutional neural network (1D-CNN) models for drilling parameter prediction. The prediction results revealed the high efficiency and accuracy of 1D-CNN regression models based on deep learning in drilling condition monitoring. Batch normalization played an essential role in the regression model training processes. Given that these parameters have different units and dimensions, we compared models with different output modes to evaluate the multiparameter prediction performance of the 1D-CNN. Taking RPM, flow rate, pressure, and WOB as independent variables and torque and ROP as dependent variables, we developed a conditional variational autoencoder to realize optimization on drilling parameters based on expected drilling performance.