bluuebunny/crossref_metadata_2025_split huggingface dataset:
A 3 month nutrition and exercise program improved hallux strength among senior daycare center users in Korea: a cluster randomized controlled trial
Authors: Sim Jiwon , Lim Jongguk , Lee Hayoung , Park Sohyun , Shin Dongsoo 
Published: July 2024

IntroductionWith a growing aging population, the focus on the health and well-being of older adults, especially in preventing falls, becomes crucial. This 3 month study, initiated in July 2022, aimed to assess the impact of a nutrition and exercise program in senior daycare centers in Chuncheon, South Korea.MethodsA 3 month study, beginning in July 2022, included 204 older adults from 10 senior daycare centers in Chuncheon, South Korea. Randomly assigned to intervention or control groups, the intervention involved nutrition, daily toe exercises, or both. Control centers received interventions post-measurements. Pre- and post-intervention analyses used paired t-tests and multiple linear regression, assessing metrics like toe grip strength for significance. While 204 were initially enrolled, the analysis included 151 participants due to dropouts.ResultsParticipants, with a mean age of 83.3 years (43.1% aged ≥ 85 years), exhibited mild to moderate cognitive impairment and multiple chronic illnesses. Health data indicated that 37.3% were obese, and the average BMI was 24.0 kg/m2. Both the intervention and control groups showed significant improvements in toe grip strength post-intervention. Specifically, the exercise-only and combined exercise-nutrition groups demonstrated significant differences in hallux strength compared to the control group after adjusting for age and gender.ConclusionThe study showed that a basic nutrition and exercise program increased toe strength in older adults with chronic diseases, including mild cognitive impairments. This intervention holds potential to prevent muscle strength decline and reduce fall risks in older individuals. As the first of its kind in Korean senior daycare centers, it emphasizes the need for future research and standardized programs for senior daycare users.
The long shadow of accumulating adverse childhood experiences on mental health in the United Arab Emirates: implications for policy and practice
Authors: Murphy Anthony , England Dawn , Elbarazi Iffat , Horen Neal , Long Toby , Ismail-Allouche Zeina , Arafat Cairo 
Published: July 2024

IntroductionThis study investigates the cumulative effects of adverse childhood experiences (ACEs) on adult depression, anxiety, and stress in Abu Dhabi, controlling for demographic factors, lifestyle, and known health and mental health diagnoses.MethodsUtilizing a cross-sectional design and self-report measures, the research aims to fill a critical gap in understanding the specific impacts of ACEs in the UAE. Based on a multi-site, cross-sectional community sample of 697 residents of Abu Dhabi.ResultsThe findings reveal significant variances in current screening values for depression, anxiety, and stress attributable to ACEs after controlling for demographic factors, lifestyle risk factors, and adult diagnoses of health and mental health conditions.DiscussionThe results underline the lifelong impact of ACEs and reinforce the importance of early identification and intervention. In particular, the implications for policy and practice in understanding and mitigating ACEs long-term effects on mental health are considered.
Ocimum basilicum and Lagenaria siceraria Loaded Lignin Nanoparticles as Versatile Antioxidant, Immune Modulatory, Anti-Efflux, and Antimicrobial Agents for Combating Multidrug-Resistant Bacteria and Fungi
Authors: El-Samahy Lamiaa A. , Tartor Yasmine H. , Abdelkhalek Adel , Pet Ioan , Ahmadi Mirela , El-Nabtity Sameh M. 
Published: July 2024

Lignin nanoparticles emerged as a promising alternative for drug delivery systems owing to their biodegradability and bioactive properties. This study investigated the antimicrobial activity of the ethanolic extract of Ocimum basilicum-loaded lignin nanoparticles (OB-LNPs) and Lagenaria siceraria seed oil-loaded lignin nanoparticles (LS-LNPs) to find a solution for antimicrobial resistance. OB-LNPs and LS-LNPs were tested for their antimicrobial potential against Escherichia coli, Enterococcus faecalis, Klebsiella pneumoniae, Staphylococcus aureus, Salmonella enterica, Trichophyton mentagrophytes, Trichophyton rubrum, and Microsporum canis. OB-LNPs and LS-LNPs were further tested for their anti-efflux activity against ciprofloxacin-resistant Salmonella enterica strains and for treating Salmonella infection in a rat model. We also investigated the antifungal efficacy of OB-LNPs and LS-LNPs for treating T. rubrum infection in a guinea pig model. Both OB-LNPs and LS-LNPs showed strong antimicrobial potential against S. Typhimurium and T. rubrum infections. LS-LNPs showed antibacterial activity against Salmonella enterica species with a MIC range of 0.5–4 µg/mL and antifungal activity against T. rubrum with a MIC range of 0.125–1 µg/mL. OB-LNPs showed antibacterial activity against Salmonella enterica species with a MIC range of 0.5–2 µg/mL and antifungal activity against T. rubrum with a MIC range of 0.25–2 µg/mL. OB-LNPs and LS-LNPs downregulated the expression of ramA and acrB efflux pump genes (fold change values ranged from 0.2989 to 0.5434; 0.4601 to 0.4730 for ramA and 0.3842–0.6199; 0.5035–0.8351 for acrB). Oral administration of OB-LNPs and LS-LNPs in combination with ciprofloxacin had a significant effect on all blood parameters, as well as on liver and kidney function parameters. Oxidative stress mediators, total antioxidant capacity, and malondialdehyde were abolished by oral administration of OB-LNPs and LS-LNPs (0.5 mL/rat once daily for 5 days). Interferon-γ and tumor necrosis factor-α were also reduced in comparison with the positive control group and the ciprofloxacin-treated group. Histopathological examination of the liver and intestine of OB-LNPs and LS-LNPs-treated rats revealed an elevation in Salmonella clearance. Treatment of T. rubrum-infected guinea pigs with OB-LNPs and LS-LNPs topically in combination with itraconazole resulted in a reduction in lesion scores, microscopy, and culture results. In conclusion, OB-LNPs and LS-LNPs possess immunomodulatory and antioxidant potential and can be used as naturally derived nanoparticles for drug delivery and treatment of Salmonellosis and dermatophytosis infections.
Pengaruh Yoga Pranayama terhadap Tingkat Stres pada Pasien Diabetes Melitus Tipe II
Authors: Marcelina Ni Putu Artamevia , Candra I Wayan 
Published: July 2024

Diabetes Melitus (DM) is a metabolic disease in which the main cause is problems with insulin secretion, insulin action or both. Patients with diabetes melitus are prone to stress. Stress that occurs can trigger physical and psychological problems. The purpose of this study was to determine the effect of pranayama yoga on the stress level of type 2 diabetes melitus patients in the UPTD Public Health Center II West Denpasar. This type of research was analytic research using a pre-experimental one-group pre-post test design. Sampling was done by simple random sampling technique. The research sample amounted to 27 people. The research instrument used the Perceived Stress Scale-10. The data analysis technique used the Wilcoxon Signed Rank Test. The results of the study before being given the intervention of yoga pranayama mild stress 5 people (18.5%), moderate stress 15 people (55.6%) and severe stress 7 people (25.9%). After the pranayama yoga intervention treatment, stress levels changed, 15 people (55,6%) mild stress and 12 (44.4%). There is a significant effect p = 0.000 between yoga pranayama on stress levels in diabetes melitus patients in the work area of UPTD Puskesmas II Denpasar Barat. Pranayama yoga can reduce the stress level of diabetes melitus patients.
Pengembangan Instrumen Smart Parenting pada Anak Usia 0-3 Tahun
Authors: Rismawan Made , Sriasih Ni Kadek , Ardhi Putra Ida Bagus , Riza Kurnia Indriana Ni Putu 
Published: July 2024

Disorders of child development have the potential to become long-term health problems. This can be prevented by carrying out child development assessments that are carried out independently by parents. However, the instruments for assessing growth and development are still conventional in the form of paper base, can only be used by health workers, and cannot be accessed by families so it would be less effective in early detection of disorders of child development. This study aimed to evaluate instruments for assessing the growth and development of children aged 0-3 years. The research design is descriptive with a Research and Development approach. This research was conducted in four villages in the Working Area of Puskesmas III Kintamani in August-September 2022. Data was collected by evaluating 284 growth and development assessment forms and Focus Group Discussions attended by seven mothers with children aged 0-3 years. The results showed that six elements in the growth and development assessment form were not found, namely the elements of the instrument usage guide, parental knowledge, assessment parameters, early detection of growth and development scores, management algorithms according to scores and health education about child growth and development. Meanwhile, there were 10 elements found but not appropriate in the child development assessment form. Participants in the Focus Group Discussion have provided input, so it is necessary to continue preparing strategic issues and consulting experts.
Economic and political prospects for the expansion of BRICS
Authors: Давыденко Е.В. 
Published: July 2024

Статья посвящена анализу и обоснованию перспектив расширения БРИКС. В исследовании определяются преимущества расширения БРИКС для стран-претендентов, стран-членов и для самого института в целом. Результаты исследования могут быть использованы для моделирования решений по вступлению государств в международные организации для усиления своих конкурентных позиций на мировой арене, могут найти отражение в формировании внешнеэкономических и внешнеполитических стратегий государств.
The article is devoted to the analysis and justification of the prospects for the expansion of BRICS. The study identifies the advantages of BRICS expansion for the applicant countries, member countries and for the institute itself as a whole. The results of the study can be used to model decisions on the entry of states into international organizations to strengthen their competitive positions on the world stage, can be reflected in the formation of foreign economic strategies of states.
Theoretical aspects of the organization of the innovation infrastructure of the national innovation system of Russia
Authors: Васильев Б.Н. 
Published: July 2024

В статье проведены теоретические исследования инновационной инфраструктуры Национальной инновационной системы. Представлены точки зрения различных ученых на ее организацию. Автором выявлены признаки построения инновационной инфраструктуры, отражающие факт того, что инфраструктура включает в себя недостающие элементы для функционирования какоголибо объекта, которые привлекаются из вне. Исследуя инфраструктурные элементы, в статье отмечено, что они представляют собой определенные услуги, которые необходимы для деятельности организаций. Также, это может быть недостающая продукция для производства, закупаемые на рынке узлы и полуфабрикаты. Инфраструктурное обеспечение включает: финансовое, производственное, технологическое, информационное, инновационное, рыночное, инженерное, транспортное, социальное, кадровое, экспертно-консалтинговое и пр. Все это отражает необходимость наличия инфраструктуры. Исследуя содержание инновационной инфраструктуры, в статье отмечено, что в настоящее время не имеется единого подхода к данному термину. Кроме этого, автором выявлено, что нет точных разделений понятий «инновационная инфраструктура» и «инфраструктура обеспечения инновационной деятельности».
The article presents theoretical studies of the innovation infrastructure of the National Innovation System. The points of view of various scientists on its organization are presented. The author identifies the signs of building an innovative infrastructure, reflecting the fact that the infrastructure includes the missing elements for the functioning of an object that are attracted from outside. Examining the infrastructure elements, the article notes that they represent certain services that are necessary for the activities of organizations. Also, it may be missing products for production, components and semi-finished products purchased on the market. Infrastructure support includes: financial, production, technological, information, innovation, market, engineering, transport, social, personnel, expert consulting, etc. All this reflects the need for infrastructure. Examining the content of the innovation infrastructure, the article notes that there is currently no single approach to this term. In addition, the author revealed that there are no exact divisions between the concepts of "innovation infrastructure" and "infrastructure for ensuring innovation activity".
Transformations of anti-crisis management of the financial sector
Authors: Костин А.Н. , Яшина Н.И. 
Published: July 2024

В статье отражены важность и актуальность трансформации антикризисного управления финансовым сектором предприятия. Подчеркнута особенная важность превентивных мероприятий антикризисного управления компании, и рассмотрены направления по разработке превентивных мероприятий. В статье автор выделил типы и классификацию кризисных явлений организаций. Цель данной статьи - отразить необходимость превентивных мероприятий антикризисного управления в структуре каждой организации. В работе выявлены два вида компаний по отношению к антикризисному явлению. Компании первого типа считают себя выше кризисов, не имеют четкого плана действий в случае их возникновения. Компании второго типа, наоборот, имеют определенный план мероприятий по антикризисному управлению. Для решения данной проблемы была дана инструкция по предотвращению кризисного состояния предприятия.
The article reflects the importance and relevance of the transformation of anti-crisis management of the financial sector of the enterprise. The special importance of preventive measures of anti-crisis management of the company is emphasized, and directions for the development of preventive measures are considered. In the article, the author singled out the types and classification of crisis phenomena in organizations. The purpose of this article is to reflect the need for preventive measures of anti-crisis management in the structure of each organization. The paper identifies two types of companies in relation to the anti-crisis phenomenon. Companies of the first type consider themselves above crises; do not have a clear plan of action in case of their occurrence. Companies of the second type, on the contrary, have a specific plan of measures for anti-crisis management. To solve this problem, instructions were given to prevent the crisis state of the enterprise.
The need for state regulation of investment processes
Authors: Хамурадов М.А. , Чаплаев Х.Г. 
Published: July 2024

Статья посвящена исследованию инвестиционных процессов и выявлению роли государства в повышении инвестиционной привлекательности и привлечения инвестиций в страну. В статье изучены различные экономические школы и теории регулирования инвестиционных процессов. На основании проведенного исследования сделаны выводы и разработаны предложения, направленные на повышение эффективности регулирования со стороны государства инвестиционных процессов.
The article is devoted to the study of investment processes and the identification of the role of the state in increasing investment attractiveness and attracting investment to the country. The article examines various economic schools and theories of regulation of investment processes. Based on the conducted research, conclusions have been drawn and proposals have been developed aimed at improving the effectiveness of state regulation of investment processes.
Formation of a digital model of spatial data management of the territory
Authors: Сумина Е.В. 
Published: July 2024

Настоящая статья посвящена исследованию и теоретическому обоснованию формирования цифровой модели управления пространственными данными территории процессов цифровой трансформации и технологического развития региона. Международная экономическая и политическая ситуация, технологические вызовы, последствия пандемии, санкций в отношении России и цикличность экономического развития с учётом особенностей каждой страны определяют необходимость новых методологических подходов к стратегическому планированию технологического развития региона. В статье компоненты цифровой модели управления территорией и ключевые задачи системы государственного убавления, пространственного развития территории на основе использования цифровых технологий. определены факторы и раскрыт механизм стратегического управления технологическим развитием региона в условиях цифровой индустриализации. Целью данного исследования является теоретическое обоснование цифровой модели управления пространственными данными территориями в целях повышения эффективности управленческих процессов, технологического развития региона, территории, новых критериев эффективности технологического развития, процесса стратегического планирования технологического развития регионов.
This article is devoted to the study and theoretical justification of the formation of a digital model of spatial data management of the territory of the processes of digital transformation and technological development of the region. The international economic and political situation, technological challenges, the consequences of the pandemic, sanctions against Russia and the cyclical nature of economic development, taking into account the characteristics of each country, determine the need for new methodological approaches to strategic planning of technological development of the region. The article describes the components of the digital model of territory management and the key tasks of the system of state reduction, spatial development of the territory based on the use of digital technologies. the factors are determined and the mechanism of strategic management of technological development of the region in the conditions of digital industrialization is revealed. The purpose of this study is the theoretical substantiation of the digital model of spatial data management of territories in order to increase the efficiency of management processes, technological development of the region, territory, new criteria for the effectiveness of technological development, the process of strategic planning of technological development of regions.
Innovative-active organizations as the basis for innovative development: a regional aspect
Authors: Субботина Н.О. 
Published: July 2024

В статье рассмотрены региональные особенности инновационной активности организаций на примере Владимирской области: обоснована актуальность исследования, приведены особенности инновационно-активных организаций. В работе представлена динамика показателей, характеризующих инновационную активность предприятий и организаций области. Особое место в статье занимает анализ деятельности инновационно-активных организаций Владимирской области. Итогом исследования является обоснование значимости инновационно-активных организации в стимулировании инновационной деятельности Владимирской области с целью обеспечения конкурентоспособности и повышения эффективности функционирования.
The article discusses the regional features of the innovative activity of organizations on the example of the Vladimir region: the relevance of the study is substantiated, the features of innovative-active organizations are given. The paper presents the dynamics of indicators characterizing the innovative activity of enterprises and organizations of the region. A special place in the article is occupied by the analysis of the activity of innovation-active organizations of the Vladimir region. The result of the study is the substantiation of the importance of innovative-active organizations in stimulating the innovative activity of the Vladimir region in order to ensure competitiveness and improve the efficiency of functioning.
Assessing the potential of a region using the state function
Authors: Крылов В.Е. 
Published: July 2024

В статье рассмотрены особенности анализа факторов внутренней среды региональной социально -экономической системы. Рассмотрены основные нормативно - правовые документы, регулирующие вопросы стратегического планирования региона. Перечислены факторы внутренней среды. Построена функция состояния, являющаяся интегральной характеристикой внутренней среды. В заключении статьи обсуждаются, плюсы и минусы функции состояния.
The article considers the features of the analysis of the factors of the internal environment of the regional socio-economic system. The main regulatory and legal documents regulating the issues of strategic planning of the region are considered. The factors of the internal environment are listed. A state function is constructed, which is an integral characteristic of the internal environment. The article concludes by discussing the pros and cons of the state function.
The Use of a Balanced Scorecard in the Digital Transformation of Tools for Assessing the Financial Stability of Enterprises Participating in the Regional Cluster
Authors: Уткин А.И. 
Published: July 2024

Статья посвящена определению возможностей цифровой трансформации инструментария оценки финансовой устойчивости предприятий-участников кластера Ивановской области. В рамках предложенного автором критериального подхода разработана методика, предусматривающая трансформацию индикаторов проекций сбалансированной системы показателей. На основе ERPсистем предложены векторы улучшения кластерного потенциала. В результате исследования в разрезе проекций выделены элементы управления трансформацией инструментария оценки финансовой устойчивости предприятий-участников регионального кластера.
The article is devoted to determining the possibilities of digital transformation of the tools for assessing the financial stability of enterprises participating in the cluster of Ivanovo region. Within the criteria-based approach proposed by the author, a methodology is developed that provides the transformation of indicators of Balanced Scorecard projections. Through ERP systems, vectors for improving cluster potential are proposed. As a result of the study, in the context of projections, the elements of transformation management tools for assessing the financial stability of enterprises participating in the regional cluster are highlighted.
Loans of the Industrial Development Fund as a tool for financing and supporting projects of manufacturing enterprises of the Samara region
Authors: Чудаева А.А. 
Published: July 2024

Статья посвящена вопросам привлечения финансирования и поддержки проектов производственных предприятий Самарской области из Фонда развития промышленности. В ней дана оценка использованию займов ФРП в качестве источника финансирования предприятиями Самарского региона, отражены ограничения и возможности по их привлечению.
The article is devoted to the issues of attracting financing and supporting projects of manufacturing enterprises of the Samara region from the Industrial Development Fund. It assesses the use of Industrial Development Fund loans as a source of financing by enterprises of the Samara region, reflects the limitations and opportunities to attract them.