bluuebunny/crossref_metadata_2025_split huggingface dataset:
A virtual bridge certificate authority‐based cross‐domain authentication mechanism for distributed collaborative manufacturing systems
Authors: Zhang Wenfang , Wang Xiaomin , Khan Muhammad Khurram 
Published: June 2014

AbstractThe virtual enterprise (VE) is a new collaborative intelligent manufacturing paradigm that pools the core competencies of its member enterprises through computer networks to exploit transient market opportunities. The successful operation of such an organization is strongly dependent on its information securities, in which cross‐domain authentication among entities of different member enterprises is a crucial issue. This problem is particularly difficult in VEs because of their collaborative nature in terms of agility, market dynamics, low cost, and diversity of collaboration modes. In this paper, we put forward a novel virtual bridge certificate authority (BCA) trust model, based on which an efficient cross‐domain authentication scheme is further presented. The proposed scheme is implemented by the distributed verifiable secret sharing protocol and the threshold elliptic curve cryptosystem signature algorithm. It has the same advantages of simple construction and short length of inter‐enterprise certification paths as the BCA model but does not need to create and maintain a dedicated physical BCA. In addition, the proposed scheme has the merits of high bit security, high efficiency, low cost, conspiracy attack resistance, and adaptability to diverse collaboration modes of VE. Therefore, the scheme is suitable for cross‐domain authentications in VEs, especially for resource‐limited applications. Copyright © 2014 John Wiley & Sons, Ltd.
Individual Differences in the Psychobiological Response to Psychosocial Stress (Trier Social Stress Test): The Relevance of Trait Anxiety and Coping Styles
Authors: Villada Carolina , Hidalgo Vanesa , Almela Mercedes , Salvador Alicia 
Published: June 2014

AbstractThe main objective of this study was to investigate the contribution of some personality traits to the physiological and psychological response to a standardized laboratory psychosocial stressor (trier social stress test). Cortisol and affective response (anxiety and mood) were analysed in a mixed‐sex group composed of 35 young adults who participated in a crossover design (18 men and 17 women). After verifying a statistically significant response to the trier social stress test in all parameters studied in both sex groups, exploratory cluster analyses were carried out to identify sub‐groups based on their psychophysiological responses. These analyses showed two different groups: subjects displaying lower psychological response along with higher cortisol response (cluster 1) compared with the group with high affective reactivity along with lower cortisol response (cluster 2). Interestingly, we also found significant differences in trait anxiety and coping styles when the two clusters were compared. Subjects in cluster 1 showed lower scores on trait anxiety and higher scores on active coping, whereas the subjects in the second cluster obtained higher scores on anxiety and on coping focused on emotions and mental disengagement. These findings support the importance of personality traits and coping styles in understanding the overall integrative psychobiological responsiveness to social stress. Copyright © 2014 John Wiley & Sons, Ltd.
Perceived Control and Psychological Contract Breach as Explanations of the Relationships Between Job Insecurity, Job Strain and Coping Reactions: Towards a Theoretical Integration
Authors: Vander Elst Tinne , De Cuyper Nele , Baillien Elfi , Niesen Wendy , De Witte Hans 
Published: June 2014

AbstractThis study aims to further knowledge on the mechanisms through which job insecurity is related to negative outcomes. Based on appraisal theory, two explanations—perceived control and psychological contract breach—were theoretically integrated in a comprehensive model and simultaneously examined as mediators of the job insecurity–outcome relationship. Different categories of outcomes were considered, namely work‐related (i.e. vigour and need for recovery) and general strain (i.e. mental and physical health complaints), as well as psychological (i.e. job satisfaction and organizational commitment) and behavioural coping reactions (i.e. self‐rated performance and innovative work behaviour). The hypotheses were tested using data of a heterogeneous sample of 2413 Flemish employees by means of both single and multiple mediator structural equation modelling analyses (bootstrapping method). Particularly, psychological contract breach accounted for the relationship between job insecurity and strain. Both perceived control and psychological contract breach mediated the relationships between job insecurity and psychological coping reactions, although the indirect effects were larger for psychological contract breach. Finally, perceived control was more important than psychological contract breach in mediating the relationships between job insecurity and behavioural coping reactions. This study meets previous calls for a theoretical integration regarding mediators of the job insecurity–outcome relationship. Copyright © 2014 John Wiley & Sons, Ltd.
Mononuclear Cells from Dedifferentiation of Mouse Myotubes Display Remarkable Regenerative Capability
Authors: Yang Zhong , Liu Qiang , Mannix Robert J. , Xu Xiaoyin , Li Hongli , Ma Zhiyuan , Ingber Donald E. , Allen Paul D. , Wang Yaming 
Published: June 2014

Abstract
Certain lower organisms achieve organ regeneration by reverting differentiated cells into tissue-specific progenitors that re-enter embryonic programs. During muscle regeneration in the urodele amphibian, postmitotic multinucleated skeletal myofibers transform into mononucleated proliferating cells upon injury, and a transcription factor-msx1 plays a role in their reprograming. Whether this powerful regeneration strategy can be leveraged in mammals remains unknown, as it has not been demonstrated that the dedifferentiated progenitor cells arising from muscle cells overexpressing Msx1 are lineage-specific and possess the same potent regenerative capability as their amphibian counterparts. Here, we show that ectopic expression of Msx1 reprograms postmitotic, multinucleated, primary mouse myotubes to become proliferating mononuclear cells. These dedifferentiated cells reactivate genes expressed by embryonic muscle progenitor cells and generate only muscle tissue in vivo both in an ectopic location and inside existing muscle. More importantly, distinct from adult muscle satellite cells, these cells appear both to fuse with existing fibers and to regenerate myofibers in a robust and time-dependent manner. Upon transplantation into a degenerating muscle, these dedifferentiated cells generated a large number of myofibers that increased over time and replenished almost half of the cross-sectional area of the muscle in only 12 weeks. Our study demonstrates that mammals can harness a muscle regeneration strategy used by lower organisms when the same molecular pathway is activated. Stem Cells 2014;32:2492–2501
Restoring Akt1 Activity in Outgrowth Endothelial Cells From South Asian Men Rescues Vascular Reparative Potential
Authors: Cubbon Richard M. , Yuldasheva Nadira Y. , Viswambharan Hema , Mercer Ben N. , Baliga Vivek , Stephen Sam L. , Askham Jonathan , Sukumar Piruthivi , Skromna Anna , Mughal Romana S. , Walker Andrew M.N. , Bruns Alexander , Bailey Marc A. , Galloway Stacey , Imrie Helen , Gage Matthew C. , Rakobowchuk Mark , Li Jing , Porter Karen E. , Ponnambalam Sreenivasan , Wheatcroft Stephen B. , Beech David J. , Kearney Mark T. 
Published: June 2014

Abstract
Recent data suggest reduced indices of vascular repair in South Asian men, a group at increased risk of cardiovascular events. Outgrowth endothelial cells (OEC) represent an attractive tool to study vascular repair in humans and may offer potential in cell-based repair therapies. We aimed to define and manipulate potential mechanisms of impaired vascular repair in South Asian (SA) men. In vitro and in vivo assays of vascular repair and angiogenesis were performed using OEC derived from SA men and matched European controls, prior defining potentially causal molecular mechanisms. SA OEC exhibited impaired colony formation, migration, and in vitro angiogenesis, associated with decreased expression of the proangiogenic molecules Akt1 and endothelial nitric oxide synthase (eNOS). Transfusion of European OEC into immunodeficient mice after wire-induced femoral artery injury augmented re-endothelialization, in contrast with SA OEC and vehicle; SA OEC also failed to promote angiogenesis after induction of hind limb ischemia. Expression of constitutively active Akt1 (E17KAkt), but not green fluorescent protein control, in SA OEC increased in vitro angiogenesis, which was abrogated by a NOS antagonist. Moreover, E17KAkt expressing SA OEC promoted re-endothelialization of wire-injured femoral arteries, and perfusion recovery of ischemic limbs, to a magnitude comparable with nonmanipulated European OEC. Silencing Akt1 in European OEC recapitulated the functional deficits noted in SA OEC. Reduced signaling via the Akt/eNOS axis is causally linked with impaired OEC-mediated vascular repair in South Asian men. These data prove the principle of rescuing marked reparative dysfunction in OEC derived from these men. Stem Cells 2014;32:2714–2723
Seröse Tumoren des Ovars
Authors: Diebold J. 
Published: June 2014

Zusammenfassung
Aufgrund verschiedener Muster molekularer Veränderungen wird heute von einem dualistischen Modell der serösen Tumoren ausgegangen, wobei seröse Borderlinetumoren (SBT) und seröse Low-grade-Karzinome (LGSC) auf der einen Seite von serösen High-grade-Karzinomen (HGSC) auf der anderen Seite unterschieden werden. Der klinische Verlauf und die Art der Therapie von SBT und LGSC hängen entscheidend davon, ob sie mit extraovariellen Manifestationen einhergehen. Sogenannte invasive Implants von SBT entsprechen morphologisch dem Bild eines LGSC. Für die Unterscheidung von LGSC und HGSC hat sich das M.D.-Anderson-Gradingsystem etabliert. HGSC weisen ein breites Spektrum an Wachstumsmustern auf, zu dem auch ein transitionalepithelähnlicher Typ gehört. Karzinosarkome sind ebenfalls als HGSC-Variante zu interpretieren. Die neue Theorie, nach der sich alle serösen Neoplasien des Ovars, Peritoneums und der Tube von den Tubenfimbrien ableiten, lässt die Bezeichnung „Ovarialkarzinom“ als nicht mehr angemessen erscheinen.
Direct genotyping of single pollen grains of a self-compatible mutant of Japanese pear (Pyrus pyrifolia) revealed inheritance of a duplicated chromosomal segment containing a second S-haplotype
Authors: Mase Nobuko , Sawamura Yutaka , Yamamoto Toshiya , Takada Norio , Nishio Sogo , Saito Toshihiro , Iketani Hiroyuki 
Published: June 2014

AbstractRadiation mutant 415-1, which is the first known diploid pollen-part self-compatible mutant of pears (Pyrus spp.), has a decreased ability to produce pollen. To determine whether the self-compatibility trait is associated with this defect, we directly analyzed the genotypes of individual pollen grains by using polymerase chain reaction amplification of DNA from single pollen grains. We isolated single pollen grains from 415-1 and succeeded in genotyping the S-RNase gene and three simple sequence repeat (SSR) markers in linkage group 17. Out of 173 individual pollen grains, 28 (16 %) were S-heteroallelic. These pollen grains had two alleles each of the S-RNase gene and of two linked SSR loci, all on a duplicated chromosomal segment, but only one allele of a non-duplicated locus farther away on the same chromosome. The segregation ratio of each marker in the pollen from 415-1 was approximately the same as that observed in outcross progeny. This suggests that the decrease in frequency of pollen with the duplicated S-haplotype occurred during meiosis or pollen formation, but that the probability of fertilization by S-heteroallelic pollen is equal to that of single-allelic pollen. However, the partial sterility in 415-1 can also be attributed to one or more unidentified lethal mutations unlinked to the duplicated segment encompassing the S-haplotype. Single-pollen genotyping can be used in a variety of applications in genetic research because in cases where all pollen genotypes are proportionately represented in the progeny, segregation ratios can be obtained without producing the next generation.
Bayesian Checks on Cheating on Tests
Authors: van der Linden Wim J. , Lewis Charles 
Published: June 2014

Posterior odds of cheating on achievement tests are presented as an alternative to p\documentclass[12pt]{minimal}
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\begin{document}$$p$$\end{document} values reported for statistical hypothesis testing for several of the probabilistic models in the literature on the detection of cheating. It is shown how to calculate their combinatorial expressions with the help of a reformulation of the simple recursive algorithm for the calculation of number-correct score distributions used throughout the testing industry. Using the odds avoids the arbitrary choice between statistical tests of answer copying that do and do not condition on the responses the test taker is suspected to have copied and allows the testing agency to account for existing circumstantial evidence of cheating through the specification of prior odds.
Effect of Bis‐(2‐ethylhexyl)Phosphoric Acid on Sodium Bis‐(2‐ethylhexyl)Phosphate Microemulsion for Selective Extraction of Non‐Ferrous Metals
Authors: Murashova N. M. , Levchishin S. Yu. , Yurtov E. V. 
Published: June 2014

AbstractThe effect of bis‐(2‐ethylhexyl)phosphoric acid (DEHPA) on the region of existence, conductivity and structure of sodium bis‐(2‐ethylhexyl)phosphate (NaDEHP) microemulsion has a dual nature and depends on DEHPA concentration. In the system NaDEHP–DEHPA–kerosene–water, the narrowing of the microemulsion region is observed with DEHPA concentration in the organic phase growth from 0.1 to 0.5 mol/L. The increase of DEHPA concentration in the organic phase from 0.1 to 0.4 mol/L leads to the reduction of electrical conductivity of the microemulsions. Based on the conductivity and viscosity measurements, we suppose the transition from reverse microemulsion with isolated droplets to percolate microemulsion at volume fraction of water 0.18 (
= 8). Droplet size of the microemulsions increases linearly with W growth. The rise of DEHPA concentration in the organic phase from 0.1 to 0.3 mol/L causes the growth of the coefficient at W in the equation d = kW + b from 0.038 to 0.249, i.e., it increases the slope of the lines. In contrast, DEHPA introduction at the concentration 0.1 mol/L (in the organic phase) leads to the expansion of the microemulsion region, does not affect the conductivity and decreases the coefficient at W. The rate of copper recovery into the microemulsion increases considerably with the rise of DEHPA concentration from 0.0 to 0.3 mol/L; no dual effect is observed. The following composition of the microemulsion for non‐ferrous metals leaching is recommended: CNaDEHP = 1.6 mol/L, CDEHPA = 0.3 mol/L (in the organic phase); W = 8–32.
Multiparameter-Genomanalyse und informationelle Selbstbestimmung
Authors: Henn W. 
Published: June 2014

Zusammenfassung
Die durch das Next Generation Sequencing real gewordene Möglichkeit kompletter Genomanalysen zu moderaten Kosten führt zu einem Paradigmenwechsel in der genetischen Labordiagnostik. Ihre Aussagekraft wird nicht mehr durch die Anzahl technisch gewinnbarer Sequenzdaten zu einer vorliegenden Fragestellung limitiert, sondern durch die Auswahl geeigneter Evaluationsparameter zur Analyse umfangreicher genomischer Sequenzdaten und deren Interpretation.
Dieser Wandel bringt neue praktische Herausforderungen für die Kommunikation mit Ratsuchenden mit sich, aber auch Regelungsbedarf zum Datenschutz angesichts einer globalisierten Medizin. Vor diesem Hintergrund muss auch das Berufsbild des Humangenetikers im Gesundheitssystem neu positioniert werden.
Time for a Revolution: Smart Energy and Microgrid Use in Disaster Response
Authors: Callaway David Wayne , Noste Erin , McCahill Peter Woods , Rossman A.J. , Lempereur Dominique , Kaney Kathleen , Swanson Doug 
Published: June 2014

AbstractModern health care and disaster response are inextricably linked to high volume, reliable, quality power. Disasters place major strain on energy infrastructure in affected communities. Advances in renewable energy and microgrid technology offer the potential to improve mobile disaster medical response capabilities. However, very little is known about the energy requirements of and alternative power sources in disaster response. A gap analysis of the energy components of modern disaster response reveals multiple deficiencies. The MED-1 Green Project has been executed as a multiphase project designed to identify energy utilization inefficiencies, decrease demands on diesel generators, and employ modern energy management strategies to expand operational independence. This approach, in turn, allows for longer deployments in potentially more austere environments and minimizes the unit's environmental footprint. The ultimate goal is to serve as a proof of concept for other mobile medical units to create strategies for energy independence. (Disaster Med Public Health Preparedness. 2014;0:1–8)
ON-FARM ECONOMIC AND ENVIRONMENTAL IMPACT OF ZERO-TILLAGE WHEAT: A CASE OF NORTH-WEST INDIA
Authors: ARYAL JEETENDRA PRAKASH , SAPKOTA TEK B. , JAT M L , BISHNOI DALIP K 
Published: June 2014

SUMMARYConducting farmers participatory field trials at 40 sites for 3 consecutive years in four rice-wheat system dominated districts of Haryana state of India, this paper tested the hypothesis that zero tillage (ZT) based crop production emits less greenhouse gases and yet provide adequate economic benefits to farmers compared to the conventional tillage (CT). In each farmer's field, ZT and CT based wheat production were compared side by side for three consecutive years from 2009–10 to 2011–12. In assessing the mitigation potential of ZT, we examined the differences in input use and crop management, especially those contributing to GHGs emissions, between ZT wheat and CT wheat. We employed Cool Farm Tool (CFT) to estimate emission of GHGs from various wheat production activities. In order to assess economic benefits, we examined the difference in input costs, net returns and cost-benefit analysis of wheat production under CT and ZT. Results show that farmers can save approximately USD 79 ha−1 in terms of total production costs and increase net revenue of about USD 97.5 ha−1 under ZT compared to CT. Similarly, benefit-cost ratio under ZT is 1.43 against 1.31 under CT. Our estimate shows that shifting from CT to ZT based wheat production reduces GHG emission by 1.5 Mg CO2-eq ha−1 season−1. Overall, ZT has both climate change mitigation and economic benefits, implying the win-win outcome of better agricultural practices.
Restoration of the genus Parasaccocoelium Zhukov, 1971 (Digenea: Haploporidae) and a description of two new species from mugilid fish in the Far East of Russia
Authors: Besprozvannykh V.V. , Atopkin D.M. , Ermolenko A.V. , Nikitenko A.Yu. 
Published: June 2014

AbstractNew data relating to the fauna of Haploporidae (Digenea) in mugilid fish from Primorsky Region of the south of the Russian Far East are presented. In the most recent revision of the family Haploporidae Nicoll, 1914, Parasaccocoelium Zhukov, 1971 was synonymized with Pseudohapladena Yamaguti, 1952 (Overstreet & Curran, 2005). Here, we restore the genus Parasaccocoelium. The species described by Zhukov can be distinguished from the species Pseudohapladena sensu Yamaguti, 1952 using a combination of the following features: (1) diffuse or absent eye-spot pigment; (2) subterminal or terminal oral sucker; (3) present or absent genital atrium; and (4) vitellarium with two large and compact vitelline masses, or vitelline follicles tubular and divided into two groups. For the species of Pseudohapladena, i.e. P. scatophagi, Yamaguti noted that the vitelline follicles occupy almost the entire post-testicular region, but in the present specimens, the vitelline follicles do not occupy the post-testicular region. Based on the diagnosis of Pseudohapladena by Overstreet & Curran (2005), the genus Parasaccocoelium differs in the following features: (1) a single testis that is longitudinal, longitudinally oval, spherical, transversally oval, irregular, bilobed or V-shaped, or a testis that is subspherical to irregular to elongate; (2) the vitellarium in the lateral fields formed from large compact follicles that have an irregular form and extend between the anterior margin of the ventral sucker or pharynx and posterior margin of the testis, and the vitelline follicles do not occupy post-testicular regions; or the vitellarium consists of elongate groups of follicles that usually extend at least one-half of a body length and extend to the posterior end of the body in some and to the posterior margin of the testis in others; (3) the eggs are operculate, unembryonated and developed when laid, or the eggs in some cases are only operculate; and (4) a developed miracidium with or without an eye spot. New data have been added to the description of Parasaccocoelium mugili Zhukov, 1971 based on new material, and two new species of this genus, Pa. haematocheilum n. sp. from Liza haematocheila and Pa. polyovum n. sp. from L. haematocheila and Mugil cephalus, are described using morphological and molecular approaches. We support the taxonomic status of the genus Parasaccocoelium and its inclusion within the sub-family Waretrematinae, and we consider Pseudohapladena lizae Liu et Yang, 2002 to be a junior synonym of Parasaccocoelium mugili Zhukov, 1971.
An ELISA kit with two detection modes for the diagnosis of lymphatic filariasis
Authors: Wongkamchai S. , Satimai W. , Loymek S. , Nochot H. , Boitano J.J. 
Published: June 2014

AbstractThe aim of this study was to develop a low-cost antifilarial immunoglobulin (Ig) G4 detection kit for the diagnosis of lymphatic filariasis. The kit was designed to be used by minimally trained personnel without the constraints of expensive laboratory equipment. We provide a description of the development and validation of a single-serum-dilution based enzyme-linked immunosorbent assay (ELISA) kit with ready-to-use reagents for measuring antifilarial IgG4 antibodies. The kit was tested on residents in Brugia malayi-endemic areas in southern Thailand. Detection was performed by naked-eye observation of the resultant colour of the immunological reactivity. The coefficient of variation (CV) was used to assess the reproducibility of the results. Long-term stability was measured over a 6-month period. Sensitivity of the test kit was 97% when compared with microfilariae detection in thick blood smears. Specificity was 98.7% based on the sera of 57 patients living outside the endemic areas who were infected with other parasites and 100 parasite-free subjects. All positive CVs were < 10%. The test kit was remarkably stable over 6 months. Field validation was performed by the detection of antifilarial IgG4 in 4365 serum samples collected from residents of brugian filariasis-endemic areas and compared with outcome colours of the test samples by the naked eye. Subsequent ELISA evaluation of these results using an ELISA reader indicated high agreement by the kappa statistic. These results demonstrate that the test kit is efficient and useful for public health laboratories as an alternative tool for the diagnosis of lymphatic filarial infection.