bluuebunny/crossref_metadata_2025_split huggingface dataset:
In vitro evaluation of flow diverter performance using a human fibrinogen–based flow model
Authors: Bilgin Cem , Bayraktar Esref Alperen , Oliver Alexander A. , Li Jiahui , Cebral Juan R. , Kallmes David F. , Kadirvel Ramanathan 
Published: July 2024

OBJECTIVE
Fibrin deposition represents a key step in aneurysm occlusion, promoting endothelization of implants and connective tissue organization as part of the aneurysm-healing mechanism. In this study, the authors introduce a novel in vitro testing platform for flow diverters based on human fibrinogen.

METHODS
A flow diverter was deployed in 4 different glass models. The glass models had the same internal parent artery (4 mm) and aneurysm (8 mm) diameters with varying parent artery angulations (paraophthalmic, sidewall, bifurcation, and slightly curved models). The neck size and area were 4 mm and 25 mm2, respectively. Human fibrinogen (330 mg/dl) was circulated within the glass models at varying flow rates (0, 3, 4, and 5 ml/sec) with or without heparin, calcium chloride, and thrombin for as long as 6 hours or until complete fibrin coverage of the flow diverter’s neck was achieved. Aneurysm neck coverage was defined as macroscopic fibrin deposition occluding the flow diverters’ pores. Flow characteristics after flow diverter deployment were assessed with computational fluid dynamics analysis. The effects of flow rates, heparin, calcium chloride, and thrombin on fibrin deposition rates were tested using 1-way ANOVA and the Tukey test.

RESULTS
A total of 84 replicates were performed. Human fibrin did not accumulate on the flow diverter stents under static conditions. The fibrin deposition rate on the aneurysm neck was significantly greater with the 5 ml/sec flow rate as compared to 3 ml/sec for all models. The paraophthalmic model had the highest inflow velocity of 48.7 cm/sec. The bifurcation model had the highest maximum shear stress (SS) and maximum normalized shear stress values at the device cells at 843.3 dyne/cm2 and 35.1 SS/SSinflow, respectively. The fibrin deposition rates of the paraophthalmic and bifurcation models were significantly higher than those of sidewall and slightly curved models for all additive or flow rate comparisons (p = 0.001 for all comparisons). The incorporation of thrombin significantly increased the fibrin deposition rates across all models (p = 0.001 for all models).

CONCLUSIONS
Rates of fibrin deposition varied widely across different configurations and additive conditions in this novel in vitro model system. Fibrin accumulation started at the aneurysm inflow zone where flow velocity and shear stress were the highest. The primary factors influencing fibrin deposition included flow velocities, shear stress, and the addition of thrombin at a physiological concentration. Further research is needed to test the clinical utility of fibrinogen-based models for patient-specific aneurysms.
Association of earlier surgery with improved postoperative language development in children with tuberous sclerosis complex
Authors: Sadeghzadeh Sina , Johnstone Thomas M. , Peters Jurriaan M. , Porter Brenda E. , Ihnen S. Katie Z. 
Published: July 2024

OBJECTIVE
The authors evaluated the impact of the timing of epilepsy surgery on postoperative neurocognitive outcomes in a cohort of children followed in the multiinstitutional Tuberous Sclerosis Complex (TSC) Autism Center of Excellence Research Network (TACERN) study.

METHODS
Twenty-seven of 159 patients in the TACERN cohort had drug-refractory epilepsy and underwent surgery. Ages at surgery ranged from 15.86 to 154.14 weeks (median 91.93 weeks). Changes in patients’ first preoperative (10–58 weeks) to last postoperative (155–188 weeks) scores on three neuropsychological tests—the Mullen Scales of Early Learning (MSEL), the Vineland Adaptive Behavior Scales, 2nd edition (VABS-2), and the Preschool Language Scales, 5th edition (PLS-5)—were calculated. Pearson correlation and multivariate linear regression models were used to correlate test outcomes separately with age at surgery and duration of epilepsy prior to surgery. Analyses were separately conducted for patients whose seizure burdens decreased postoperatively (n = 21) and those whose seizure burdens did not (n = 6). Regression analysis was specifically focused on the 21 patients who achieved successful seizure control.

RESULTS
Age at surgery was significantly negatively correlated with the change in the combined verbal subtests of the MSEL (R = −0.45, p = 0.039) and predicted this score in a multivariate linear regression model (β = −0.09, p = 0.035). Similar trends were seen in the total language score of the PLS-5 (R = −0.4, p = 0.089; β = −0.12, p = 0.014) and in analyses examining the duration of epilepsy prior to surgery as the independent variable of interest. Associations between age at surgery and duration of epilepsy prior to surgery with changes in the verbal subscores of VABS-2 were more variable (R = −0.15, p = 0.52; β = −0.05, p = 0.482).

CONCLUSIONS
Earlier surgery and shorter epilepsy duration prior to surgery were associated with greater improvement in postoperative language in patients with TSC. Prospective or comparative effectiveness clinical trials are needed to further elucidate surgical timing impacts on neurocognitive outcomes.
Microbial etiology of vertebral osteomyelitis/discitis amid the opioid epidemic
Authors: Ammerman S. Alexander , Keister Alexander , Vignolles-Jeong Joshua , Mallory Noah , Gibbs David C. , Eaton Ryan G. , Ma Jianing , Xu David S. , Viljoen Stephanus , Grossbach Andrew J. 
Published: July 2024

OBJECTIVE
The primary goal of this study was to establish the current microbial trends in vertebral osteomyelitis/discitis (VOD) amid the opioid epidemic and to determine if intravenous drug use (IVDU) predisposes one to a unique microbial profile of infection.

METHODS
The authors performed a retrospective cohort study consisting of 1175 adult patients diagnosed with VOD between 2011 and 2022 at a single quaternary center. Data were acquired through retrospective chart review, with pertinent demographic and clinical information collected.

RESULTS
Staphylococcus aureus was the most cultured organism in both the IVDU and non-IVDU groups at 56.1% and 40.7%, respectively. In the IVDU cohort, Serratia marcescens was the next most prevalently cultured organism at 13.9%.

CONCLUSIONS
The present study demonstrates that in the IVDU population S. marcescens is an organism of high concern. The potential for Serratia spp. infection should be accounted for when selecting empirical antimicrobial therapy in VOD patients.
Improving Learning Outcomes Pencak Silat T Kick Using Chair Aids for Class 4 Students at SD Muhammadiyah Pucang Gading Mranggen Demak Academic Year 2023/2024
Authors: Priyanto Catur Wahyu 
Published: July 2024

Penelitian yang bertujuan untuk meningkatkan hasil belajar tendangan T dalam cabang olahraga pencak silat melalui alat bantu kursi pada siswa kelas 4 SD Muhammadiyah Pucang Gading Semarang. Metode yang digunakan yaitu metode Penelitian Tindakan Kelas dengan teknik penelitian tes dan observasi, penelitian dilakukan dua siklus dengan setiap siklus berdasarkan empat tahapan. Jumlah sisiwa yang dijadikan responden dalam satu kelas 33 siswa. Berdasarkan hasil atau data penelitian, terdapat peningkatan dari pra siklus ke siklus I dan siklus II. Peningkatan terlihat progresif dari setiap kenaikan dalam KKTP (kriteria ketercapaian tujuan pembelajaran) siswa dari data pra siklus dinyatakan tercapai 7 siswa (21,21%), hasil belajar siklus I dinyatakan tercapai 15 siswa (45,45%), hasil belajar sisklus II dinyatakan tercapai 30 siswa (90,91%). Dengan demikian alat kursi dapat meningkatkan hasil belajar tendangan T pencak silat siswa kelas 4 SD Muhammadiyah Pucang Gading Mranggen Demak.
Analisis Strategi Gender Terhadap Pendidikan Anak Keluarga Petani Jambu Di Demak
Authors: Sari Risti Lia , Astuti Wulan Budi , Fatimah Asa Salma 
Published: July 2024

Women's issues are still an important thing to discuss, in addition to continuing to develop, also many women's problems are never exhausted by a time or era of their presence on the surface of the earth, this is very visible when talking about the low resources of women, the problem of violence against women that occurs a lot either in the public or other sectorsThis research is a type of field research with qualitative research methods. Field research is research carried out at the research location or in the field. This technique is carried out by means of observation and recording on the object of study. The focus of observation is carried out on three main components, namely space, actors and activities. which aims to determine perceptions in providing education and efforts of guava farmer families in educating their daughters and sons. The results of this study attempt to determine the perception of guava farmer families in educating their daughters and sons are by distinguishing behavioral factors, age factors, interest factors, physical activity factors, biological development factors, closeness factors to both parents, and favorite
Levels Estimation of Iron, Zinc and Copper in the Serum of Children Infected with Giardiasis
Authors: Taher Huda Mawlood 
Published: July 2024

Giardiasis is an infection in the small intestine, it’s caused by a microscopic parasite called Giardia lamblia. In this study, we examined stool samples for 75 children, 1–12 years old during the period from August to November 2023 from children who attended a pediatric hospital in Kirkuk city, and we estimated the levels of iron, zinc, and copper in these children. A stool examination was done for all samples to detect cysts or trophozoites of Giardia lamblia. Also, we measured the levels of iron, zinc, and copper by atomic absorption spectrophotometer. The highest rate of parasite infection (66.7%) was recorded in the age group (4–6 )years old. Serum iron and copper levels considerably decreased (P<0.05) in comparison to the control group. It was noted that most of the infected children suffer from abdominal pain with intermittent diarrhea.
Determinan Keputusan Memilih Program Studi Manajemen : Pendekatan Kuantitatif pada Mahasiswa Universitas Dirgantara Marsekal Suryadarma
Authors: Permatasari Rita Intan , Nalurita Sari 
Published: July 2024

Banyak cara yang telah dilakukan Program Studi S-1 Manajemen Unsurya dalam mengenalkan kampus dan prodinya melalui beberapa kegiatan dengan mitra sekolah dan peranan sosial media. Hasil observasi melihat kecenderungan mahasiswa memilih kuliah di Prodi Manajemen Unsurya dikarenakan minat karena keinginan sendiri sebanyak 59,4 persen, ajakan teman sebanyak 25 persen, saran orang tua sebanyak 12,5 persen, dan sisanya 3,1 persen karena dekat dengan rumah. Sampel penelitian adalah mahasiswa aktif Program Studi Manajemen angkatan 2020-2023 yang berjumlah 238 orang dengan menggunakan metode penelitian secara deskriptif kuantitatif (inferensia). Teknik sampling atau teknik penarikan sampel secara random acak menggunakan metode slovin diperoleh 150 sampel mahasiswa. Ada tiga variabel yang diteliti yaitu Minat, Motivasi dan Keputusan Memilih Program Studi. Pengumpulan data menggunakan kuesioner google form diperoleh hasil : (1) minat berpengaruh signifikan terhadap Keputusan Memilih Program Studi Manajemen di Unsurya, (2) motivasi berpengaruh signifikan terhadap Keputusan Memilih Program Studi Manajemen di Unsurya dan (3) minat dan motivasi berpengaruh signifikan secara bersama-sama terhadap Keputusan Memilih Program Studi Manajemen di Unsurya sebesar 61,4 %.
Pedagogical Relevance of Irresistible Lexical Items Used in Online Media: A Case Study of Urdu Speakers, India
Authors: Dedy Suhery  , Mohd Hamid Raza  , M. Yusuf Hasbalnikistan  
Published: July 2024

This paper attempts to determine the account of the irresistible lexical items used in online media, examine the pedagogical strategies that impacted the cycle of the psychological expressions, and generalize the media's applications attracted to the learners' intentions through the features of irresistible lexical items. The researchers used qualitative descriptive with several techniques, including collecting data from Urdu speakers (participants) who used the irresistible lexical items in language teaching. And then, after reading newspapers, magazines, gadgets, books, journals, etc., the researchers generalized the ideas and concepts of the learners. The account of the irresistible lexical items' pedagogical relevance in online media could improve the Urdu speakers and affect the pedagogical levels, particularly in speaking. The pedagogical structure shapes the teachers' actions, judgments, and other teaching strategies and considers the learners' needs, backgrounds, and understanding. In addition, Language teaching adopts the linguistic framework of the lexical items and affects the medium of communication. Even similar words may be present in its language, affecting the pedagogical structure of language teaching.
Pendampingan Mewujudkan Lingkungan Hidup Bersih dan Sehat Bersama Masyarakat Sungai Pulai Melalui Kegiatan Ecobricks
Authors: Ulfah Siti Mariah , Septiana Rahma 
Published: July 2024

Kesehatan Lingkungan Merupakan imbas dari menjaga kebersihan, Salah satu komponen lingkungan hidup yaitu kesehatan lingkungan dan kesehatan masyarakat. Salah satu permasalahan untuk mewujudkan lingkungan yang bersih dan sehat adalah menumpuknya sampah di masyarakat, menanggulangi sampah yang diproduksi oleh masyarakat baik sampah organik maupun sampah anorganik merupakan permasalahan umum di masyarakat. Melalui Pengabdian masyarakat (PKM) ini bertujuan untuk untuk memberikan penyuluhan dan pelatihan tentang penanggulangan sampah baik sampah organik maupun anorganik dengan mendaur ulang sampah anorganik melalui kegiatan ecobricks, dan sampah organik menjadi pupuk Organik Cair (POC), PKM ini menggunakan pendekatan Participatory Action Research (PAR) dengan metode PRA. Kegiatan ini menghasilkan Ecobriks perabot rumah tangga yaitu kursi dari bahan sampah plastik dan dari sampah rumah tangga dibuat pupuk organik Cair.(POC). Respon masyarakat sangat antusias dan kegiatan ini harus ada tindak lanjut karena keberhasilan PKM ini diukur tidak hanya selama proses namun harus ada tindak lanjutnya agar lingkungan hidup bersih dan sehat dapat terwujud.
Peculiarities of The Progressive, Perfect and Future Formation in Colloquial Arabic
Authors: Al-Jarf Reima 
Published: July 2024

Arabic has three tenses: past, present and future. The past tense refers to actions that took place in the past (كتب kataba He wrote). The present tense pertains to habitual actions, or those that are currently ongoing (يكتب /yaktubu/ He writes). The future signifies actions expected to occur in the future by adding the prefix س /sa/ or the particle سوف /sawfa/ to the present tense form of the verb (سيكتب sa-yaktubu He will write). Arabic also has a perfect and an imperfect aspect, an active participle (كاتب /ka:tib/ writer) and a passive participle (مكتوب /maktu:b/ (written). Stretches of discourse containing the progressive markers عمال عم &باش and active participle forms of sense, motion, and volition verbs as امشي walk, تعال come here, قوم get up; جالس sitting, قاعد sitting, أروح go, سامع hearing, شايف seeing and others were collected from informants and social media posts in order to find out how the aforementioned particles, lexical verbs and participles are used to express the progressive and future aspects in spoken Colloquial Arabic dialects and the grammaticalization process they went through (desemanticization, decategorization, extension and erosion). Data analysis revealed that the particles باش/ماش (will) and هيا (let’s), verbs as خلينا , هيا,امشي , قوم(let’s), express futurity. Other aspectual particles as عم عمال (are), and verbs of motion, posture, volition and sense and active participles express the Progressive Tense. In some cases, active participles of verbs of motion, posture and volition are ambiguous denoting multiple tenses and aspects as Present Progressive, Past Progressive, Present Perfect depending on the context and availability of adverbs of time. In some case active participles undergo a grammaticalization process where they change from a lexical verb to an aspect marker. Results of the study are given in detail.
REPRODUCTIVE AND GROWTH PERFORMANCE OF FOUR GENOTYPES OF RABBITS FED WITH TOASTED CHRISTMAS BUSH FRUITS (Alchornea cordifolia) SEED MEAL
Authors: SAMSON ADE , ADIMABUA M.M , IRIKEFE-EKEKE E.P. , SANUBI J.O. , OBAKANURHE O. 
Published: July 2024

The body weight and reproductive performance of four genotypes of rabbits fed with toasted Alchornea cordifolia seed meal were examined in the study, as well as the body weight performance of their first filial generation and their reciprocal crosses. Toasted Alchornea cordifolia seed meal (TASM) inclusion was to know the (%) level that will perform better. The mating ratio of 1 sire to 9 dams in combinations of Dutch black buck and New Zealand does (DTB X NZW), New Zealand buck and Dutch black does (NZW X DTB), and then their reciprocal crosses resulted in a total of 127 kittens (NZW X DTB). The treatment diets were formulated at different levels to meet the rabbit’s nutritional requirements. Rabbits were kept in hutches inside rabbit’s pens, and feed and water were provided ad libitum. Reproductive and body weight were recorded. Preliminary and phytochemical analysis of the TASM revealed that it has values of 20.00%, 90.30%, 14.50%, 12.00%, 1.05%, and 65.2% for crude protein, dry matter, Ether extract, crude fiber, Ash, and Nitrogen-free extract, and phytochemical contains 6.50mg/g and 86.05mg/g for phytic acid and tannins. From the experiment, it is revealed that the rabbit fed on 15% TASM (NZW X DTB) significantly (p˂0.05) had a better body weight and reproductive performance than other groups. The findings of this study show that TASM can be incorporated into rabbits' diets up to 15% inclusion level for better weight gain and reproductive efficiency without having any negative impact on the animal.
Quantifying of runC, Kata and gVisor in Kubernates
Authors: Purwoko Rahmat , Priambodo Dimas Febriyan , Prasetyo Arbain Nur 
Published: July 2024

The advent of container technology has emerged as a pivotal solution for application developers, addressing concerns regarding the seamless execution of developed applications during the deployment process. Various low-level container runtimes, including runC, Kata Container, and gVisor, present themselves as viable options for implementation. The judicious selection of an appropriate low-level container runtime significantly contributes to enhancing the efficiency of Kubernetes cluster utilization. To ascertain the optimal choice, comprehensive testing was conducted, encompassing both performance and security evaluations of the low-level container runtimes. This empirical analysis aids developers in making informed decisions regarding the selection of low-level container runtimes for integration into a Kubernetes cluster. The performance assessments span five key parameters: CPU performance, memory utilization, disk I/O efficiency, network capabilities, and the overall performance when executing an nginx web server. Three distinct tools—sysbench, iperf3, and Apache Benchmark—were employed to conduct these performance tests. The findings of the tests reveal that runC exhibits superior performance across all five parameters evaluated. However, a nuanced consideration of security aspects is imperative. Both Kata Container and gVisor demonstrate commendable host isolation, presenting limited vulnerability to exploitation. In contrast, runC exposes potential vulnerabilities, allowing for exploits against the host (worker node), such as unauthorized directory creation and system reboots. This comprehensive analysis contributes valuable insights for developers, facilitating an informed decision-making process when selecting low-level container runtimes within a Kubernetes environment.
Evaluation of Machine Learning Models for Predicting Cardiovascular Disease Based on Framingham Heart Study Data
Authors: Suhatril Ruddy J , Syah Rama Dian , Hermita Matrissya , Gunawan Bhakti , Silfianti Widya 
Published: July 2024

The Framingham Heart Study Community is a research community that produces data related to Cardiovascular Disease (CVD). This research applies technology to predict CVD using machine learning based on data from the Framingham Heart Study. The eight machine learning algorithms are deployed in this study, they are decision tree, naïve bayes, k-nearest neighbors, support vector machine, random forest, logistic regression, neural network, and gradient boosting.This research uses several stages of research such as load dataset, preprocessing data, data modeling, evaluation of various data modelling, and input new data. The best performance was produced by the random forest model with an accuracy value of 0.84, a precision value of 0.84, a recall value of 0.85, an f1-score value of 0.79 and an AUC value of 0.72. The prediction generated by the proposed machine learning model is high risk or low risk of CVD.
Penerapan Sistem Informasi Geografis Terhadap Pemetaan Letak Wisata Kabupaten Bondowoso Menggunakan Leaflet JS Berbasis Web
Authors: Muhtarom Muhammad Rifki , Lutfi Ahmad , Susanto Adi 
Published: July 2024

Bepergian untuk pariwisata adalah perpindahan sementara orang ke suatu lokasi tertentu. Segala kegiatan sosial yang berkaitan dengan pengunjung, baik lokal maupun asing, disebut pariwisata; salah satu kegiatan tersebut adalah pariwisata di kabupaten Bondowoso. dibangunlah sistem informasi geografis berbasis web untuk memudahkan wisatawan dalam memperoleh informasi pariwisata khususnya mengenai rute perjalanan di Kota Bondowoso. Ide yang melatarbelakangi pengembangan sistem informasi geografis ini. Pariwisata tidak terlepas dari yang namanya rute, untuk mendapatkan rute terpendek digunakanlah Algoritma Dijkstra dan metode siklus hidup pengembangan System, dataset yang digunakan ialah perjalanan dari Dinas pariwisata Bondowoso menuju Alun alun Bondowoso, ditemukan hasil dari perhitungan Algoritma Dijkstra yaitu jarak terdekat dimulai dari simpul A – B – E – H - J.