bluuebunny/crossref_metadata_2025_split huggingface dataset:
Septic Shock, Tubular Necrosis, and Central Diabetes Insipidus: A Challenging Syndrome
Authors: Melegari Gabriele , Manenti Antonio , Arturi Federica , Gualdi Eugenia , Filoni Sonia , Zelent Gabriele , Barbieri Alberto 
Published: July 2024

Abstract
Background
The association between septic shock, acute tubular necrosis, and central diabetes insipidus is infrequent: our recent clinical observation invited us to deepen its pathophysiological features.

Methods
We reported an unusual case report of a young, healthy man with a septic shock, severe dehydration with a hematocrit of 70.6% caused by gastrointestinal infection and refractory renal failure, and persistent polyuria.

Results
The patient presented severe dehydration, hypovolemic shock with a hematocrit of 70.6%, and acute renal failure. The subsequent laboratory exams demonstrated a gastrointestinal infection of Campylobacter Upsaliensis and Helicobacter pylori. The persistent renal failure and polyuria later 20 days made it mandatory for further investigations. A Magnetic brain Resonance excluded encephalic lesions but demonstrated a posterior pituitary lobe hypointense.

Conclusions
This cascade of pathological events seems originated from a septic shock: the consequent increase in hematocrit and blood viscosity, estimated double the normal, with severe hypotensive shock correlated, decelerated the microcirculatory blood flow, until a proper blood stasis in the venous system. These factors caused hypoxia and possible venous thromboses, electively affecting the pituitary hypothalamic nuclei and their axons in the post-hypophysis and its portal system.
Flood risk assessment in Kogi State Nigeria through the integration of hazard and vulnerability factors
Authors: Aladejana Olabanji Odunayo , Ebijuoworih Etari Joy 
Published: July 2024

AbstractAnnually, Kogi State in Nigeria experiences significant flooding events, leading to serious fatalities, the destruction of livelihoods, and damage to vital infrastructure. This study presents a multi-faceted approach and methodology to generate a state-wide flood risk map by analyzing both flood vulnerability and flood hazard factors. Seven flood hazard factors (drainage length, distance to river, elevation, slope, rainfall, distance from confluence/dam area, and geomorphology) and vulnerability factors (population density, female population, land cover, road length, distance from hospitals, literacy rate, and employment rate) were ranked and weighted based on their contributions to flooding within the state using the Fuzzy Analytical Hierarchy Process (FAHP). From these, the Flood Hazard Index (FHI), Flood Vulnerability Index (FVI), and Flood Risk Index (FRI) were derived. Results showed that Kabba, Idah, Olamabor, Kotonkar, and the southern part of Ajaokuta LGAs exhibit high flood vulnerability due to dense populations, remoteness from roads and critical infrastructure, and considerable distances from healthcare facilities. Likewise, LGAs exhibiting a very high FHI occur along the geographic zones bounded by the confluence of the Niger and Benue rivers, specifically along the Lokoja area, and the Kotonkar, Kogi, Bassa, and Ibaji LGAs. Five flood risk classes—very low, low, moderate, high, and very high FRI classes—occupy 26.82, 31.12, 22.07, 15.26, and 4.71% of the area, respectively. Out of 295 villages, 65 villages are spread across the high flood risk zone. The safest LGAs include Ankpa, Omala, Dekina, Ijumu, Kabba, and Mopa-Muro LGAs.
Guide Field Dependence of Energy Conversion and Magnetic Topologies in Reconnection Turbulent Outflow
Authors: Xiong Q. Y. , Huang S. Y. , Zhang J. , Yuan Z. G. , Jiang K. , Wu H. H. , Lin R. T. , Yu L. , Tang Y. T. 
Published: July 2024

AbstractEnergy conversion between the fields and the particles occurs through various physical processes within space environments. Magnetic reconnection stands out as one such process capable of rapidly and massively releasing energy. The high‐speed outflow jets produced by reconnection can induce turbulence characterized by intermittent structures. In this study, we investigate the impact of guide field on the energy conversion associated with the magnetic topologies within these structures during reconnection. Utilizing both particle‐in‐cell simulations and observations from the Magnetospheric Multiscale mission, our findings suggest that a larger guide field present during reconnection leads to increased energy conversion as well as the generation of O‐type topology structures within the turbulent outflow. Our results provide significant evidence on the relationships between energy conversion and magnetic topologies within turbulent outflow of reconnection and the guide field conditions.
Simultaneous de novo calling and phasing of genetic variants at chromosome-scale using NanoStrand-seq
Authors: Bai Xiuzhen , Chen Zonggui , Chen Kexuan , Wu Zixin , Wang Rui , Liu Jun’e , Chang Liang , Wen Lu , Tang Fuchou 
Published: July 2024

AbstractThe successful accomplishment of the first telomere-to-telomere human genome assembly, T2T-CHM13, marked a milestone in achieving completeness of the human reference genome. The upcoming era of genome study will focus on fully phased diploid genome assembly, with an emphasis on genetic differences between individual haplotypes. Most existing sequencing approaches only achieved localized haplotype phasing and relied on additional pedigree information for further whole-chromosome scale phasing. The short-read-based Strand-seq method is able to directly phase single nucleotide polymorphisms (SNPs) at whole-chromosome scale but falls short when it comes to phasing structural variations (SVs). To shed light on this issue, we developed a Nanopore sequencing platform-based Strand-seq approach, which we named NanoStrand-seq. This method allowed for de novo SNP calling with high precision (99.52%) and acheived a superior phasing accuracy (0.02% Hamming error rate) at whole-chromosome scale, a level of performance comparable to Strand-seq for haplotype phasing of the GM12878 genome. Importantly, we demonstrated that NanoStrand-seq can efficiently resolve the MHC locus, a highly polymorphic genomic region. Moreover, NanoStrand-seq enabled independent direct calling and phasing of deletions and insertions at whole-chromosome level; when applied to long genomic regions of SNP homozygosity, it outperformed the strategy that combined Strand-seq with bulk long-read sequencing. Finally, we showed that, like Strand-seq, NanoStrand-seq was also applicable to primary cultured cells. Together, here we provided a novel methodology that enabled interrogation of a full spectrum of haplotype-resolved SNPs and SVs at whole-chromosome scale, with broad applications for species with diploid or even potentially polypoid genomes.
A high-quality genome assembly and annotation of Thielaviopsis punctulata DSM102798
Authors: Purayil Gouthaman P. , Saeed Esam Eldin , Mathai Archana M. , El-Tarabily Khaled A. , AbuQamar Synan F. 
Published: July 2024

AbstractBlack scorch disease (BSD), caused by the fungal pathogen Thielaviopsis punctulata (Tp) DSM102798, poses a significant threat to date palm cultivation in the United Arab Emirates (UAE). In this study, Chicago and Hi-C libraries were prepared as input for the Dovetail HiRise pipeline to scaffold the genome of Tp DSM102798. We generated an assembly with a total length of 28.23 Mb comprising 1,256 scaffolds, and the assembly had a contig N50 of 18.56 kb, L50 of three, and a BUSCO completeness score of 98.6% for 758 orthologous genes. Annotation of this assembly produced 7,169 genes and 3,501 Gene Ontology (GO) terms. Compared to five other Thielaviopsis genomes, Tp DSM102798 exhibited the highest continuity with a cumulative size of 27.598 Mb for the first seven scaffolds, surpassing the assemblies of all examined strains. These findings offer a foundation for targeted strategies that enhance date palm resistance against BSD, and foster more sustainable and resilient agricultural systems.
Cyclic quantum teleportation of two-qubit entangled states by using six-qubit cluster state and six-qubit entangled state
Authors: Slaoui A. , El Kirdi M. , Ahl Laamara R. , Alabdulhafith M. , Chelloug S. A. , Abd El-Latif A. A. 
Published: July 2024

AbstractCyclic quantum teleportation schemes requires at least the existence of three collaborators acting all as senders and receivers of quantum information, each one of them has an information to be transmitted to the next neighbour in a circular manner. Here, new cyclic quantum teleportation scheme is proposed for perfectly transmitting cyclically three arbitrary unknown two-qubit states ($$\alpha $$
α
, $$\beta $$
β
and $$\gamma $$
γ
) among the three collaborators. In this scheme, Alice can send to Bob the quantum information contained in her two-qubit state $$\alpha $$
α
and receive from Charlie the quantum information contained in the two-qubit state in his possession $$\gamma $$
γ
and similarly, Bob can transmit to Charlie the quantum information contained in his two-qubit state $$\beta $$
β
through a quantum channel of twelve-qubit state consisting of a six-qubit cluster state and a six-qubit entangled state by sequentially and cyclically performing Bell state measurements. Subsequently, each one of the three participants can afterwards retrieve his own desired two-qubit state using classical channel and by performing appropriate unitary Pauli operators and we have shown that our proposed scheme performs efficiently.
Enhanced carbon dioxide drainage observed in digital rock under intermediate wetting conditions
Authors: Azpiroz Jaione Tirapu , Giro Ronaldo , Neumann Barros Ferreira Rodrigo , Nogueira Pereira da Silva Marcio , Fernandes Blanco Rodriguez Manuela , Lopez Adolfo E. Correa , Vasquez David A. Lazo , Esteves Ferreira Matheus , Del Grande Mariana , Ferreira Da Silva Ademir , Steiner Mathias B. 
Published: July 2024

AbstractCarbon dioxide (CO$$_2$$

2

) trapping in capillary networks of reservoir rocks is a pathway to long-term geological storage. At pore scale, CO$$_2$$

2

drainage displacement depends on injection pressure, temperature, and the rock’s interaction with the surrounding fluids. Modeling this interaction requires adequate representations of both capillary volume and surface. For the lack of scalable representations, however, the prediction of a rock’s CO$$_2$$

2

storage potential has been challenging. Here, we report how to represent a rock’s pore space by statistically sampled capillary networks (ssCN) that preserve morphological rock characteristics. We have used the ssCN method to simulate CO$$_2$$

2

drainage within a representative sandstone sample at reservoir pressures and temperatures, exploring intermediate- and CO$$_2$$

2

-wet conditions. This wetting regime is often neglected, despite evidence of plausibility. By raising pressure and temperature we observe increasing CO$$_2$$

2

penetration within the capillary network. For contact angles approaching 90$$^\circ$$

∘

, the CO$$_2$$

2

saturation exhibits a pronounced maximum reaching 80$$\%$$
%
of the accessible pore volume. This is about twice as high as the saturation values reported previously. For enabling validation of our results and a broader application of our methodology, we have made available the rock tomography data, the digital rock computational workflows, and the ssCN models used in this study.
Liver fibrosis as a predictor of liver failure and outcome following ALPPS among patients with primary liver cancer
Authors: Zhang Junwei , Zhang Lei , Yang Xiaobo , Zheng Yongchang , Xu Haifeng , Du Shunda , Mao Yilei , Sang Xinting , Zhao Haitao , Xu Yiyao , Lu Xin 
Published: July 2024

AbstractThe influence of liver fibrosis on the rate of liver regeneration and complications following ALPPS has yet to be fully understood. This study aimed to scrutinize the effects of liver fibrosis on the postoperative complications, and prognosis subsequent to ALPPS. Clinical data were collected from patients with primary liver cancer who underwent ALPPS at Peking Union Medical College Hospital between May 2014 and October 2022. The degree of liver fibrosis was assessed using haematoxylin–eosin staining and Sirius red staining. This study encompassed thirty patients who underwent ALPPS for primary liver cancer, and there were 23 patients with hepatocellular carcinoma, 5 with cholangiocarcinoma, and 2 with combined hepatocellular-cholangiocarcinoma. The impact of severe liver fibrosis on the rate of liver regeneration was not statistically significant (P = 0.892). All patients with severe complications belonged to the severe liver fibrosis group. Severe liver fibrosis exhibited a significant association with 90 days mortality (P = 0.014) and overall survival (P = 0.012). Severe liver fibrosis emerges as a crucial risk factor for liver failure and perioperative mortality following the second step of ALPPS. Preoperative liver function impairment is an important predictive factor for postoperative liver failure.
Formation of the junctions between lymph follicles in the Peyer's patches even before postweaning activation
Authors: Teshigahara Anri , Banba Yuri , Yoshida Hiromi , Kaji Mitsuji , Zhou Zhou , Koyama Nao , Sakai Yoshifumi , Karrow Niel A. , Ogasawara Kouetsu , Hirakawa Ryota , Islam Jahidul , Furukawa Mutsumi , Nochi Tomonori 
Published: July 2024

AbstractPeyer’s patches (PPs), which contain an abundance of B and T cells, play a key role in inducing pivotal immune responses in the intestinal tract. PPs are defined as aggregated lymph follicles, which consist of multiple lymph follicles (LFs) that may interact with each other in a synergistic manner. LFs are thought to be spherical in shape; however, the characteristics of their structure are not fully understood. To elucidate changes in the structure of PPs as individuals grow, we generated serial 2D sections from entire PPs harvested from mice at 2, 4, and 10 weeks of age and performed a 3D analysis using a software, Amira. Although the number of LFs in PPs was not changed throughout the experiment, the volume and surface area of LFs increased significantly, indicating that LFs in PPs develop continuously by recruiting immune cells, even after weaning. In response to the dramatic changes in the intestinal environment after weaning, the development of germinal centers (GCs) in LFs was observed at 4 and 10 weeks (but not 2 weeks) of age. In addition, GCs gradually began to form away from the center of LFs and close to the muscle layer where export lymphatic vessels develop. Importantly, each LF was joined to the adjacent LF; this feature was observed even in preweaning nonactivated PPs. These results suggest that PPs may have a unique organization and structure that enhance immune functions, allowing cells in LFs to have free access to adjacent LFs and egress smoothly from PPs to the periphery upon stimulation after weaning.
Embedding textile capacitive sensing into smart wearables as a versatile solution for human motion capturing
Authors: Geißler Daniel , Zhou Bo , Bello Hymalai , Sorysz Joanna , Ray Lala , Javaheri Hamraz , Rüb Matthias , Herbst Jan , Zahn Esther , Woop Emil , Bian Sizhen , Schotten Hans D. , Joost Gesche , Lukowicz Paul 
Published: July 2024

AbstractThis work presents a novel and versatile approach to employ textile capacitive sensing as an effective solution for capturing human body movement through fashionable and everyday-life garments. Conductive textile patches are utilized for sensing the movement, working without the need for strain or direct body contact, wherefore the patches can sense only from their deformation within the garment. This principle allows the sensing area to be decoupled from the wearer’s body for improved wearing comfort and more pleasant integration. We demonstrate our technology based on multiple prototypes which have been developed by an interdisciplinary team of electrical engineers, computer scientists, digital artists, and smart fashion designers through several iterations to seamlessly incorporate the technology of capacitive sensing with corresponding design considerations into textile materials. The resulting accumulation of textile capacitive sensing wearables showcases the versatile application possibilities of our technology from single-joint angle measurements towards multi-joint body part tracking.
Demequina capsici sp. nov., a novel plant growth-promoting actinomycete isolated from the rhizosphere of bell pepper (Capsicum annuum)
Authors: Humaira Zalfa , Cho Donghyun , Peng Yuxin , Avila Forbes , Park Yu Lim , Kim Cha Young , Lee Jiyoung 
Published: July 2024

AbstractDemequina, commonly found in coastal and marine environments, represents a genus of Actinomycetes. In this study, strains Demequina PMTSA13T and OYTSA14 were isolated from the rhizosphere of Capsicum annuum, leading to the discovery of a novel species, Demequina capsici. Bacteria play a significant role in plant growth, yet there have been no reports of the genus Demequina acting as plant growth-promoting bacteria (PGPB). Comparative genomics analysis revealed ANI similarity values of 74.05–80.63% for PMTSA13T and 74.02–80.54% for OYTSA14, in comparison to various Demequina species. The digital DNA-DNA hybridization (dDDH) values for PMTSA13T ranged from 19 to 39%, and 19.1–38.6% for OYTSA14. Genome annotation revealed the presence of genes associated with carbohydrate metabolism and transport, suggesting a potential role in nutrient cycling and availability for plants. These strains were notably rich in genes related to ‘carbohydrate metabolism and transport (G)’, according to their Cluster of Orthologous Groups (COG) classification. Additionally, both strains were capable of producing auxin (IAA) and exhibited enzymatic activities for cellulose degradation and catalase. Furthermore, PMTSA13T and OYTSA14 significantly induced the growth of Arabidopsis thaliana seedlings primarily attributed to their capacity to produce IAA, which plays a crucial role in stimulating plant growth and development. These findings shed light on the potential roles of Demequina strains in plant–microbe interactions and agricultural applications. The type strain is Demequina capsici PMTSA13T (= KCTC 59028T = GDMCC 1.4451T), meanwhile OYTSA14 is identified as different strains of Demequina capsici.
Sex-specific survival gene mutations are discovered as clinical predictors of clear cell renal cell carcinoma
Authors: Hwang Jia , Lee Hye Eun , Han Jin Seon , Choi Moon Hyung , Hong Sung Hoo , Kim Sae Woong , Yang Ji Hoon , Park Unsang , Jung Eun Sun , Choi Yeong Jin 
Published: July 2024

AbstractAlthough sex differences have been reported in patients with clear cell renal cell carcinoma (ccRCC), biological sex has not received clinical attention and genetic differences between sexes are poorly understood. This study aims to identify sex-specific gene mutations and explore their clinical significance in ccRCC. We used data from The Cancer Genome Atlas-Kidney Renal Clear Cell Carcinoma (TCGA-KIRC), The Renal Cell Cancer-European Union (RECA-EU) and Korean-KIRC. A total of 68 sex-related genes were selected from TCGA-KIRC through machine learning, and 23 sex-specific genes were identified through verification using the three databases. Survival differences according to sex were identified in nine genes (ACSS3, ALG13, ASXL3, BAP1, JADE3, KDM5C, KDM6A, NCOR1P1, and ZNF449). Female-specific survival differences were found in BAP1 in overall survival (OS) (TCGA-KIRC, p = 0.004; RECA-EU, p = 0.002; and Korean-KIRC, p = 0.003) and disease-free survival (DFS) (TCGA-KIRC, p = 0.001 and Korean-KIRC, p = 0.000004), and NCOR1P1 in DFS (TCGA-KIRC, p = 0.046 and RECA-EU, p = 0.00003). Male-specific survival differences were found in ASXL3 (OS, p = 0.017 in TCGA-KIRC; and OS, p = 0.005 in RECA-EU) and KDM5C (OS, p = 0.009 in RECA-EU; and DFS, p = 0.016 in Korean-KIRC). These results suggest that biological sex may be an important predictor and sex-specific tailored treatment may improve patient care in ccRCC.
The impact of scavenging air state on the combustion and emission performance of marine two-stroke dual-fuel engine
Authors: Yu Hongliang , Gao Jianqun , Zhang Peng , Han Fang Jun , Yang Qizheng , Cui Bin 
Published: July 2024

AbstractThe scavenging process significantly affects the combustion and emission performance of marine low-speed two-stroke dual-fuel engines. Optimizing scavenging air pressure and temperature can enhance the engine's combustion efficiency and emission control performance, thereby achieving more environmentally friendly and efficient operation of dual-fuel engines. This study focuses on marine low-speed two-stroke dual-fuel engines, analyzing the effects of scavenging air pressure (3.0 bar, 3.25 bar, 3.5 bar, and 3.75 bar) and scavenging air temperature (293 K, 303 K, and 313 K) on engine performance and emission products. The results indicate that scavenging air pressure has a greater impact on engine performance than scavenging air temperature. An increase in scavenging air pressure leads to higher thermal efficiency and power. As the scavenging air pressure increases from 3 to 3.75 bar, the indicated thermal efficiency (ITE) increases from 44.02 to 53.26%, and indicated mean effective pressure (IMEP) increases by approximately 0.35 MPa. Increased scavenging air pressure improves nitrogen oxide (NOx) and hydrocarbons (HC) emissions. For every 0.25 bar increase in scavenging air pressure, NOx emissions decrease by 3.53%, HC emissions decrease by 33.35%, while carbon dioxide (CO2) emissions increase by 0.71%. An increase in scavenging air temperature leads to lower ITE and IMEP. As the air temperature changes from 293 to 313 K, the ITE decreases by approximately 1%, and IMEP decreases by about 0.04 MPa. Increased scavenging air temperature improves CO2 emissions. For every 10 K increase in the air temperature, the CO2 emissions decrease by 0.02%, while NOx emissions increase by 4.84%, HC emissions increase by 34.39%. Therefore, controlling scavenging air pressure is more important than scavenging air temperature in the operational management of marine two-stroke engines. Higher power and lower NOx and HC emissions can be achieved by increasing the scavenging air pressure.
Neural network-based algorithm for door handle recognition using RGBD cameras
Authors: Mochurad Lesia , Hladun Yaroslav 
Published: July 2024

AbstractThe ability to recognize and interact with a variety of doorknob designs is an important component on the path to true robot adaptability, allowing robotic systems to effectively interact with a variety of environments and objects The problem addressed in this paper is to develop and implement a method for recognizing the position of a door handle by a robot using data from an RGBD camera. To achieve this goal, we propose a revolutionary approach designed for autonomous robots that allows them to identify and manipulate door handles in different environments using data obtained from RGBD cameras. This was achieved by creating and annotating a complete dataset consisting of 5000 images of door handles from different angles, with the coordinates of the vertices of the bounding rectangles labeled. The architectural basis of the proposed approach is based on MobileNetV2, combined with a special decoder that optimally increases the resolution to 448 pixels. A new activation function specially designed for this neural network is implemented to ensure increased accuracy and efficiency of raw data processing. The most important achievement of this study is the model's ability to work in real-time, processing up to 16 images per second. This research paves the way for new advancements in the fields of robotics and computer vision, making a substantial contribution to the practical deployment of autonomous robots in a myriad of life's spheres.