bluuebunny/crossref_metadata_2025_split huggingface dataset:
Coexisting choroidal neovascularization and active retinochoroiditis—an uncommon presentation of ocular toxoplasmosis
Authors: Hegde Sharat , Relhan Nidhi , Pathengay Avinash , Bawdekar Abhishek , Choudhury Himadri , Jindal Animesh , Flynn Harry W 
Published: July 2015

Abstract

Background
Choroidal neovascularization during the active stage of Toxoplasma retinochoroiditis is an uncommon clinical presentation. The authors retrospectively reviewed medical charts of patients with coexisting choroidal neovascular membrane and active Toxoplasma retinochoroiditis.

Findings
Three patients presented with coexisting choroidal neovascular membrane and active Toxoplasma retinochoroiditis. All lesions had adjacent subretinal hemorrhage. The diagnosis was confirmed based on clinical presentation, fundus fluorescein angiography (FFA), and optical coherence tomography (OCT) findings. The patients were managed with a combination of treatments including intravitreal injection of anti-vascular endothelial growth factor (anti-VEGF), oral anti-Toxoplasma treatment, and oral corticosteroids. In all patients, the retinitis lesion resolved in 6 weeks and the coexisting choroidal neovascular membrane resolved over 6 to 12 weeks.

Conclusions
Recurrences in Toxoplasma retinochoroiditis are common as satellite lesions adjacent to an old atrophic scar. Coexisting choroidal neovascularization with active Toxoplasma retinochoroiditis is an important presentation and should be suspected in the presence subretinal hemorrhage and managed with a combination of anti-Toxoplasma treatment and intravitreal anti-VEGF.
Elucidation of monocyte/macrophage dynamics and function by intravital imaging
Authors: Rua Rejane , McGavern Dorian B 
Published: July 2015

Abstract
Monocytes and macrophages are a diverse population of innate immune cells that play a critical role in homeostasis and inflammation. These cells are surveillant by nature and closely monitor the vasculature and surrounding tissue during states of health and disease. Given their abundance and strategic positioning throughout the body, myeloid cells are among the first responders to any inflammatory challenge and are active participants in most immune-mediated diseases. Recent studies have shed new light on myeloid cell dynamics and function by use of an imaging technique referred to as intravital microscopy (IVM). This powerful approach allows researchers to gain real-time insights into monocytes and macrophages performing homeostatic and inflammatory tasks in living tissues. In this review, we will present a contemporary synopsis of how intravital microscopy has revolutionized our understanding of myeloid cell contributions to vascular maintenance, microbial defense, autoimmunity, tumorigenesis, and acute/chronic inflammatory diseases.
Id2 deletion attenuates Apc-deficient ileal tumor formation
Authors: Biyajima Kyoko , Kakizaki Fumihiko , Shen Xiaodong , Mori Kentaro , Sugai Manabu , Taketo M. Mark , Yokota Yoshifumi 
Published: July 2015

ABSTRACT
The expression level of inhibitor of DNA binding 2 (Id2) is increased in colorectal carcinomas and is positively correlated with poor prognosis. However, the functional significance of Id2 in intestinal tumorigenesis has not been fully defined using genetic approaches. Here, we show that Id2 promotes ileal tumor initiation in Apc-deficient mice. Expression of Id2 was stimulated by Wnt signaling through the enhancer region of the Id2 promoter at the early stage of tumorigenesis in Apc+/Δ716 (ApcΔ716) mice. Genetic depletion of Id2 in ApcΔ716 mice caused ∼80% reduction in the number of ileal polyps, but had little effect on tumor size. Notably, the lack of Id2 increased the number of apoptotic cells in the normal crypt epithelium of the mice. Furthermore, DNA microarray analysis revealed that the expression level of Max dimerization protein 1 (Mxd1), known as a c-Myc antagonist, was specifically increased by Id2 deletion in the ileal intestinal epithelium of ApcΔ716 mice. In contrast, the protein level of c-Myc, but not the mRNA level, was decreased by loss of Id2 in these mice. These results indicate that loss of Id2 inhibits tumor initiation by up-regulation of Mxd1 and down-regulation of c-Myc in ApcΔ716 mice.
Unraveling dual feeding associated molecular complexity of salivary glands in the mosquitoAnopheles culicifacies
Authors: Sharma Punita , Sharma Swati , Mishra Ashwani Kumar , Thomas Tina , Das De Tanwee , Rohilla Suman Lata , Singh Namita , Pandey Kailash C. , Valecha Neena , Dixit Rajnikant 
Published: July 2015

ABSTRACTMosquito salivary glands are well known to facilitate meal acquisition, however the fundamental question on how adult female salivary gland manages molecular responses during sugar versus blood meal uptake remains unanswered. To investigate these responses, we analyzed a total of 58.5 million raw reads generated from two independent RNAseq libraries of the salivary glands collected from 3–4 day-old sugar and blood fed Anopheles culicifacies mosquitoes. Comprehensive functional annotation analysis of 10,931 contigs unraveled that salivary glands may encode diverse nature of proteins in response to distinct physiological feeding status. Digital gene expression analysis and PCR validation indicated that first blood meal significantly alters the molecular architecture of the salivary glands. Comparative microscopic analysis also revealed that first blood meal uptake not only causes an alteration of at least 12–22% of morphological features of the salivary glands but also results in cellular changes e.g. apoptosis, confirming together that adult female salivary glands are specialized organs to manage meal specific responses. Unraveling the underlying mechanism of mosquito salivary gene expression, controlling dual feeding associated responses may provide a new opportunity to control vector borne diseases.
Two species of Sapromyza new to Slovakia with note on S. zetterstedti Hendel 1908 / Dva nové druhy rodu Sapromyza pre Slovensko s poznámkou k druhu S. zetterstedti Hendel 1908
Authors: Semelbauer Marek 
Published: July 2015

Abstract
Sapromyza viciespunctata and S. bisigillata are introduced as new species to Slovakia. A brief description and photographs of adults as well as drawing of terminalia are provided. The presence of S. zetterstedti in the territory of Slovakia is briefly discussed
Convergence Between Kazakhstan’S Financial Systemand International Standards: Overcoming Difficulties
Authors: Uvarova Natalya 
Published: July 2015

Abstract
This article deals with the convergence of the Kazakh financial system with international standards in light of the new, enhanced agreement with the European Union on partnership and cooperation (January 19, 2015). Based on this research, the approaches used by the Kazakh financial system to converge with the European Union (EU) and the mechanism of implementing international standards in the national regulatory framework are determined. In practice, the study provides justification for the necessity of arranging the systematization of existing rules and regulations covering financial activity in the Republic, eliminating discrepancies between the national regulatory framework and international standards, and determining clear security guarantees for foreign investors’ financial activity in the Republic. The research results are primarily focused on the development of public finance management theory. Theories and conclusions present in the study can be used in the educational processes of economic and legal institutions and in the policymaking activity of public finance management bodies.
Preventing intellectual disability during pregnancy: what are the potentially high yield targets?
Authors: Wang Yinding , McDermott Suzanne , Mann Joshua R. , Hardin James W. 
Published: July 2015

AbstractTo identify risk factors among children with unknown cause intellectual disability (ID) and to estimate the population-attributable risk (PAR) associated with these factors.This was a retrospective cohort study of maternal and child pairs born between 2004 and 2010 in South Carolina, and information was obtained from Medicaid billing records, birth certificates, and other administrative data. The data included 123,922 children and logistic generalized estimating equations (GEE) regression models were used to estimate the association of maternal risk factors and ID. We estimated models with and without birth weight as a covariate, since low birth weight is known to be a mediator of the association between some risk factors and ID in children.The prevalence of ID in the children was 3.85% and the associations between risk factors and ID were similar for female and male children. We found that the odds of having ID were increased if a child’s mother had a diagnosis of major depression; for male children, the odds ratio (OR) was 1.34 (95% confidence interval [CI] 1.14–1.59, PAR 2.17%); and for females, the OR was 1.59 (95% CI 1.30–1.95, PAR 4.70%). The odds of having ID were also increased for children of women with bipolar disorder (males – OR 1.95, 95% CI 1.53–2.48, PAR 2.85%; females – OR 1.63, 95% CI 1.20–2.22, PAR 2.05%).Major maternal depression and bipolar disorder were each significantly associated with the odds of ID in children, each accounting for approximately 2–5% of the PAR, when controlling for covariates.
Effects of preeclampsia on the amplitude integrated electroencephalography activity in preterm infants
Authors: Topcuoglu Sevilay , Kolsuz Leyla Daban , Gursoy Tugba , Ovali Fahri , Karatekin Guner 
Published: July 2015

AbstractPreeclampsia leads to chronic intrauterine hypoxia by interfering with placental blood supply. The aim of this study was to investigate whether preeclampsia exposure has an influence on the central nervous system of infants, as monitored by amplitude integrated electroencephalography (aEEG).We recruited 52 infants with gestational age between 30 and 34 weeks. Twenty-seven infants were born to preeclamptic mothers, and 25 gestational age-matched infants whose mothers were healthy were enrolled as a control group. aEEG recordings were performed between 24 and 48 h of life using a cerebral function monitor (CFM) (Olympic Brainz monitor). Along with aEEG, middle cerebral artery (MCA) blood flow velocities (BFV) were measured using Doppler ultrasound.The duration of quiet sleep was significantly shorter (P=0.001), and Burdjalov score was lower (P=0.04) in the preeclampsia group. However, there was no change in MCA BFV in this group.Preeclampsia altered cerebral electrical activity of premature infants born to preeclamptic mothers.
Pseudo almost periodic and automorphic mild solutions to nonautonomous neutral partial evolution equations
Authors: Akdad Abdelkarim-Nidal , Ezzinbi Khalil , Souden Lotti 
Published: July 2015

AbstractIn this work, we present a new concept of Stepanov weighted pseudo almost periodic and automorphic
functions which is more generale than the classical one, and we obtain a new existence result of
μ-pseudo almost periodic and μ-pseudo almost automorphic mild solutions for some nonautonomous evolution
equations with Stepanov μ-pseudo almost periodic terms. An example is shown to illustrate our results.
Crystal structure of 3-{[4-(4-fluorophenyl)piperazin-1-yl]methyl}-5-(thiophen- 2-yl)-2,3-dihydro-1,3,4-oxadiazole-2-thione, C17H17FN4OS2
Authors: Al-Omary Fatmah A. M. , AlRabiah Haitham , Ghabbour Hazem A. , Quah Ching Kheng , Fun Hoong-Kun , El-Emam Ali A. 
Published: July 2015

Abstract C17H17FN4OS2, triclinic, P1̅ (no. 2), a = 6.3278(8) Å, b = 9.6250(13) Å, c = 14.789(2) Å, α = 81.739(5)°, β = 82.226(4)°, γ = 76.611(4)°, V = 862.3 Å3, Z = 2, Rgt(F) = 0.0798, wRref(F2) = 0.2072, T = 150 K.
The “monster” of Seymour Avenue: Internet crime news and Gothic reportage in the case of Ariel Castro
Authors: Arntfield Michael 
Published: July 2015

AbstractWhile American media reportage of heinous crimes has long drawn on Gothic iconography to secure readers, the contemporary digital news market has engendered a trend in crime reporting that transparently imparts the conventions of Victorian horror, and by extension the nineteenth-century American Gothic. Employing a semiotic content analysis of Internet news stories (
Acanthocephalans Of The Genus Centrorhynchus (Palaeacanthocephala, Centrorhynchydae) From Birds Of Ukraine With The Description Of A New Species
Authors: Lisitsyna O. I. , Greben O. B. 
Published: July 2015

Abstract
The article presents the results of the investigation of material on the genus Centrorhynchus Lühe, 1911 stored in the collection of the Department of Parasitology, Schmalhauzen Institute of Zoology, National Academy of Sciences of Ukraine. Five species: Centrorhynchus aluconis, C. globocaudatus, C. spinosus, C. conspectus and C. polissiensis sp. n. were studied and described. Centrorhynchus polissiensis sp. n., differs from all known species by the complex morphological characters, in particular, by the formula of proboscis hooks in combination with the number of large hooks with roots, by the number of hooks in anterior part of the proboscis, and by comparatively smaller eggs. C. polissiensis sp. n. is most similar to C. aluconis, C. conspectus and C. globocaudatus. The main differences between the species are in the proboscis armament, 13–17 hooks in a longitudinal row in C. aluconis, 16–18 hooks in C. conspectus vs 19–20 hooks in C. polissiensis sp. n., and in the egg sizes, 56–65 × 28–30 for C. aluconis, 68–72 × 33–35 for C. conspectus vs 45–55 × 25 for C. polissiensis sp. n. C. polissiensis sp. n. differs from C. globocaudatus in shape and morphology of the proboscis hooks. We do not confirm the record of C. amphibius from birds of the territory of Ukraine. The data on synonymy, hosts and distribution in Ukraine and in the world are given for seven species of the genus recorded in Ukraine. Illustrated descriptions about the material of collection are presented for five species. We provide an identification key for nine species of the genus Centrorhynchus of the birds of the fauna of Ukraine and adjacent territories.
Comparative Genomics Reveals Chd1 as a Determinant of Nucleosome Spacing in Vivo
Authors: Hughes Amanda L , Rando Oliver J 
Published: July 2015

Abstract
Packaging of genomic DNA into nucleosomes is nearly universally conserved in eukaryotes, and many features of the nucleosome landscape are quite conserved. Nonetheless, quantitative aspects of nucleosome packaging differ between species because, for example, the average length of linker DNA between nucleosomes can differ significantly even between closely related species. We recently showed that the difference in nucleosome spacing between two Hemiascomycete species—Saccharomyces cerevisiae and Kluyveromyces lactis—is established by trans-acting factors rather than being encoded in cis in the DNA sequence. Here, we generated several S. cerevisiae strains in which endogenous copies of candidate nucleosome spacing factors are deleted and replaced with the orthologous factors from K. lactis. We find no change in nucleosome spacing in such strains in which H1 or Isw1 complexes are swapped. In contrast, the K. lactis gene encoding the ATP-dependent remodeler Chd1 was found to direct longer internucleosomal spacing in S. cerevisiae, establishing that this remodeler is partially responsible for the relatively long internucleosomal spacing observed in K. lactis. By analyzing several chimeric proteins, we find that sequence differences that contribute to the spacing activity of this remodeler are dispersed throughout the coding sequence, but that the strongest spacing effect is linked to the understudied N-terminal end of Chd1. Taken together, our data find a role for sequence evolution of a chromatin remodeler in establishing quantitative aspects of the chromatin landscape in a species-specific manner.
Examining Sport Team Identification, Social Connections, and Social Well-being among High School Students
Authors: Wann Daniel L. , Waddill Paula J. , Brasher Matthew , Ladd Sagan 
Published: July 2015

Past research has found that sport team identification is positively correlated with social psychological health (Phua, 2012; Wann & Weaver, 2009) including work testing adolescent fans (Wann, Brasher, Thomas, & Scheuchner, in press). The current study was designed to extend previous investigations by examining the relationship between team identification and the establishment and maintenance of social connections. Data from 177 high school students confirmed expectations as identification with a high school football team was positively correlated with both social well-being and social connections. However, social connections were not found to mediate the relationship between identification and well-being, contrary to the team identification – social psychological health model (Wann, 2006b).
AS MÁSCARAS DO TEXTO
Authors: Lobo Suely Maria De Paula e Silva 
Published: July 2015

<p>Este ensaio procura evidenciar o caráter de construção do texto literário e os procedimentos lúdicos que visam à criação de efeitos que irão se constituir como máscaras encobridoras / reveladoras de sentidos possíveis no espaço de encenação da palavra.</p><p> </p>
VINICIUS, CANTOR DO SUBMUNDO
Authors: Menezes Roniere 
Published: July 2015

Neste ensaio, buscamos aproximar a literatura produzida pelo poeta Vinicius de Moraes de alguns conceitos presentes na obra de Jacques Derrida. Vinicius foi um homem preocupado com o seu tempo, em termos estéticos e políticos. Escreveu peças teatrais, poemas, crônicas e canções, em que tematiza os seres tornados opacos pela dinâmica da vida social. O autor busca iluminar, e acolher, com sua escritura, os indivíduos desalojados do projeto da modernidade.
O EU E O OUTRO: A RECEPÇÃO CRÍTICA DE AUGUSTO DOS ANJOS
Authors: Machado Maria Zélia Versiani 
Published: July 2015

<p>Ressaltar a importância da história da crítica na recuperação do incessante movimento de leituras do <em>Eu</em>, de Augusto dos Anjos, é o objetivo deste ensaio, que se desdobra também como leitura da configuração fundadora de uma poética contemporânea.</p>
Nurse Navigation and the Transition to Cancer Survivorship: A Review of Determinants Essential to Program Success
Authors: Giunti Amanda 
Published: July 2015

<div class="page" title="Page 26"><div class="layoutArea"><div class="column"><p><span>Nurse navigation programs are becoming prominent in the field of cancer care. As a newly emerging field, nurse navigation employs nurses and other health care profes- sionals who assist patients in overcoming barriers throughout the cancer continuum. The concept of nurse navigation is being extended to focus on survivorship, which is described as the period following active cancer treatment where patients often en- counter barriers affecting their care and quality of life. By utilizing specific skills and modalities, including education, communication, and coordination, survivorship navigators are able to assist in reducing disparities such as knowledge and communi- cation inadequacies, thus, facilitating optimal access to survivorship care. Access to health services is an important determinant of health in Canada. Survivorship navi- gation programs incorporate health services, providing a method in which cancer patients can overcome challenges and improve their health outcomes. This review will discuss the origins of nurse navigation, highlight navigator skills and modalities, which are essential to program success, and finally discuss the implications of a sur- vivorship navigation program. </span></p></div></div></div>
Potencial germinativo de sementes de Aroeira Myracrodruon urundeuva Fr. coletadas de população no cariri paraibano
Authors: Diniz Raquel de Queiroz , Diniz Belísia Lúcia Moreira Toscano , Azeredo Gilvaneide Alves de , Souza Vênia Camelo de , Pereira Emanuel Moreira 
Published: July 2015

<p>A aroeira (<em>Myracrodruon urundeuva</em>)é uma espécie pioneira que apresenta ampla distribuição geográfica, podendo ser encontrada em rios, córregos, como também em terrenos secos e pedregosos. Na comunidade vegetal no Sítio Quixaba, Taperoá, PB, não mais se observa uma quantidade grande de indivíduos como existia há anos atrás. Diante da importância que a espécie possui, este trabalho visa avaliar o potencial germinativo de sementes provenientes de oito indivíduos coletadas em uma população vegetal localizada no Sítio Quixaba no município de Taperoá.PB. O experimento foi conduzido sob condições controladas (laboratório/25ºC) e não controladas (viveiro). Foram avaliadas as seguintes características: germinação, índice de velocidade de germinação (IVG) e tempo médio de germinação, durante um período de 30 dias. Nas condições de viveiro, após um período de 70 dias, foram avaliadas as seguintes variáveis: altura de plantas, número de folhas, diâmetro de colo, massa seca de raiz e de parte aérea. O delineamento foi inteiramente casualizado com oito tratamentos (indivíduos) e quatro repetições de 25 sementes. Houve variação na qualidade fisiológica das sementes provenientes dos indivíduos da população de aroeira localizada no Sítio Quixaba em Taperoá-PB; sugere-se que estudos fenológicos sejam desenvolvidos na população estudada e em outras existentes no Sítio Quixaba para entendimento do comportamento germinativo e de vigor das sementes.</p><p><strong> </strong></p>
Investigação etnobotânica das plantas medicinais utilizadas para o tratamento de faringoamigdalite no CRAS de Cuité, PB
Authors: Alencar Monyelle Yvine de Andrade , Costa Danielly Albuquerque da , Souza Júlia Beatriz Pereira de , Alencar Maria Carmem Batista de , Carmo Egberto Santos 
Published: July 2015

<p>O presente trabalho é um estudo etnobotânico realizado com idosos do CRAS (Centro de Referência de Assistência Social) que investigou o conhecimento popular sobre plantas medicinais para o tratamento de faringoamigdalite no município de Cuité localizado no Curimataú do estado da Paraíba. Essa comunidade mais idosa possui um conhecimento muito grande em relação ao uso de plantas medicinais. Desta forma, o estudo tem por objetivo investigar, documentar e avaliar se há confirmação científica de que a plantas medicinais utilizadas por esta comunidade realmente possuem atividades antimicrobianas. Para esta investigação foi realizada uma pesquisa exploratória, através de entrevistas aplicando-se um questionário semiestruturado com perguntas objetivas e subjetivas, buscando informações sobre o conhecimento da faringoamigdalite e de plantas utilizadas para o tratamento da mesma. A amostra foi composta por trinta idosos. Alguns entrevistados relataram nunca ter utilizado plantas medicinais ou nunca ter apresentado faringoamigdalite, mas os que relataram o uso de plantas medicinais citaram 14 espécies vegetais, consideradas úteis para o tratamento da doença. A principal planta citada por esta comunidade foi a romã (<em>Punica granatum)</em> possuidora de atividade antimicrobiana confirmada cientificamente contra <em>Streptococcus pyogenes </em>umas das bactérias causadora da faringoamigdalite. Os dados obtidos revelam que a comunidade possui conhecimento sobre plantas medicinais com atividade antimicrobiana para tratamento de faringoamigdalite.</p>