bluuebunny/crossref_metadata_2025_split huggingface dataset:
2366 – Booster Sessions After Cognitive-behavioral Group Therapy For Panic Disorder: Impact On Resilience, Coping And Quality Of Life
Authors: Heldt E. , Wesner A.C. , Gomes J.B. , Detzel T. , Guimarães L. 
Published: July 2013

IntroductionPanic Disorder (PD) tends to chronicity and one of the risk factors is the use of maladaptive coping strategies to deal with stressful events.ObjectiveTo evaluate the response to booster sessions with cognitive techniques of coping strategies on resilience and on quality of life (QoL) of patients who received standard cognitive-behavioral group therapy (CBGT) for PD.MethodsA controlled clinical trial with 44 patients with PD (intervention= 20 and control= 24) who previously completed the 12-week CBGT protocol. PD, anxiety, and depression severity symptoms were assessed at baseline and 1, 6 and 12 months after the booster sessions. Coping strategies, resilience and QoL were assessed by Coping Strategies Inventory (CSI), Resilience Scale and WHOQOL-BREF, respectively.ResultsConsidering the outcome ‘time,’ a significant improvement of PD and depression symptoms was observed in both groups. A significant increase in QoL domain of social relations for the intervention group was found, considering a time*group interaction. There was no significant difference on coping and other QoL domains. Changes on resilience were dependent on the symptoms intensity, and the correlations were negative.ConclusionsThe improvement of PD and depression symptoms for both groups may be related to the therapeutic factors of the group sessions format. Therefore, booster sessions with groups after CBGT may benefit patients with PD regardless the use of specific cognitive techniques.
2372 – Preliminary Psychometric Characteristics Of The Portuguese Version Of Patient Health Questionnaire 9 (phq-9) In a Sample Of Portuguese Breast Cancer Women
Authors: Torres A. , Pereira A. , Monteiro S. , Albuquerque E. 
Published: July 2013

IntroductionDepression, anxiety and distress are common during the course of cancer. Studies suggest prevalence of distress greater than 30%. Distress and depression influence quality of life. However, depression is often overlooked by cancer professionals. It is needed short and easy instruments to help to assess depression symptoms and its severity. PHQ-9 is an example of a short instrument to assess depressive symptoms and its severity.ObjectivesIn this work the preliminary study of the psychometric characteristics of PHQ-9 in a sample of breast cancer Portuguese women is described.AimsWe purpose to evaluate psychometric characteristics of PHQ-9 in a Portuguese sample, namely: internal consistency, test-retest reliability and concurrent validity.MethodsPsychometric analyses were performed on a sample composed of 49 breast cancer women, with ages from 30 to 80 years old (M = 59.27, SD = 11.12). Participants answered to PHQ-9 twice (with a 2 months interval) and once to Hospital Anxiety and Depression Scale (HADS). The procedure enclose: translation; back translation; discussion group for inspection of lexical equivalence and content validity and application to a target population.ResultsIt was obtained a Cronbach alpha of .82. The test-retest reliability show a significant statistical positive correlation (rS = .82, p = .000). Significant positive statistical correlation with HADS was also observed (rS = .60, p = .000 for anxiety and rS = .65, p = .000 for depression).ConclusionsThe validation of the Portuguese PHQ-9 has good psychometric proprieties of internal consistency, test-retest reliability and concurrent validity. Therefore, we can conclude that PHQ-9 is a useful and a valid scale.
2448 – Adolescent Subthreshold Depression and Anxiety
Authors: Balazs J. 
Published: July 2013

A significant proportion of individuals with substantial functional impairment who either identify themselves as psychiatric patients or who are referred for psychiatric evaluation by their families/teachers or other clinicians may not receive a standard diagnosis based on the current classification systems due to an insufficient number or duration of symptoms. Their conditions are labeled as subthreshold mental disorders. This presentation aims to give an overview on the current knowledge on adolescent subthreshold depression and anxiety.Based on the literature the presence of subthreshold depression and anxiety is associated with more medical comorbidity, more workdays lost, greater use of services for medical and mental health problems and increased suicide risk. Adolescents with subthreshold conditions have an increased risk for developing future full syndrome disorders than individuals without these conditions. People with subthreshold conditions report significantly more social dysfunction and disability compared to those with several common general medical conditions such as hypertension or diabetes.The results of the Saving and Empowering Young Lives in Europe (SEYLE) study - as the risk for increased burden of disease and suicide risk among adolescents with subthreshold-depression/anxiety is between the risk for those non-depressed/nonanxious and full syndrome depressed/anxious - contribute to the current discussions about the advantages and disadvantages of categorical and dimensional classification systems: these findings suggest that subthreshold and full DSM-IV-TR depression/anxiety could be on the same continuum. Inputting subthreshold disorders into the diagnostic systems could provide a bridge between categorical and dimensional diagnostic models.
2531 – Clinical Psychopathology
Authors: Stanghellini G. 
Published: July 2013

Clinical psychopathology aims at the identification of symptoms that are significant in view of nosographical distinctions. Schneider affirms that this discipline aims at becoming the “psychopathological doctrine of symptoms and diagnosis” - the link between descriptive psychopathology and nosography. It restricts the task of the psychopathological inquiry to the search for diagnostically relevant symptoms being interested in eliciting first and foremost those abnormal psychic phenomena that help the clinician to establish a reliable diagnosis.Although clinical psychopathology is at risk of flattening the practice of psychopathology to that of nosographical diagnosis, it also serves an epistemologically important function since it is concerned with generalizing the individual case and subsuming it into a general category. It complements the view of descriptive psychopathology (which keeps the individual and its complexity in focus) in that the patient here is also an instantiation of a general category, rather than merely a primordially real individual. Psychopathology is not only about the description of phenomena idiosyncratically taking place in a single individual - although its first aim is to do justice to the individuum. It also envisions the individual as an exemplar of a given general type.Psychopathology is a kind of scientific knowledge since it allows generalizations. It keeps in tension the knowledge about the real individual (e.g this person with schizophrenia) with the horizonal knowledge of an abstract kind (what psychopathology knows about the condition called ‘schizophrenia’). Knowledge emerges as the mutual enlightenment between the individual and the genre he is attributed to.
2547 – Prevention and Early Intervention in Postpartum Depression Risk
Authors: Gigantesco A. , Palumbo G. , Mirabella F. , Cascavilla I. 
Published: July 2013

Post-partum depression is a significant public health problem. Birth and neonatal outcomes suffer as a result of maternal depression. As such, effectively treating depression is imperative to the overall health of mother and child.Psychopharmacological interventions are effective in alleviating depresses symptoms. However, the evidence of the safety of their use during nursing is inconclusive. Moreover, women themselves express the desire for non-psychopharmacological options when deciding to manage their depression.The efficacy of specific psychological interventions for the prevention and treatment of post-partum depression has been addressed recently by several studies. in 2011, the Mental Health Department of the Italian National Institute of Health (ISS) received a grant from the Ministry of Health to assess, in Italy, the feasibility and efficacy in actual practice of the demonstrably effective approach based on clinical work and research conducted by Milgrom J. at the Infant Clinic of the Parent-Infant Research Institute, Austin & Repatriation Medical Centre, in Melbourne, Australia (Milgrom J, Negri LM, Gemmill AW, McNeil M, Martin PR., 2005). The preliminary results of that assessment will be presented at the congress.
2577 – Prevalence of Risk Behaviours and Psychopathology Among European Youth
Authors: Carli V. , Wasserman C. , Sarchiapone M. , Hoven C. , Wasserman D. 
Published: July 2013

During the transition from childhood to adulthood, adolescents establish patterns of behaviour and make lifestyle choices that affect both their current and future health. Most health indicators are socially patterned in adolescence and track into adulthood, with higher risks of adverse outcomes. Given the importance of this transitional period, it is essential to systematically monitor and assess the health and well-being of adolescents and young adults, and evaluate the nation’s efforts to improve the health of young people.Saving and Empowering Young Lives in Europe (SEYLE) aims at promoting mental health among adolescents in European schools. The SEYLE project was performed during January 2009 - December 2011, and comprised a consortium of 12 European countries: Austria, Estonia, France, Germany, Hungary, Ireland, Israel, Italy, Romania, Slovenia and Spain, with Sweden as the coordinating centre. One of its main objectives is to gather information on health and well-being in European adolescents. SEYLE generated a large epidemiological database containing information regarding sociodemographics, risk factors, lifestyles, and the mental health of adolescents in Europe. The database contains information regarding 366 variables for 12,395 cases, for a total of over 4.5 million observations. Prevalence regarding psychopathology, such as depressive and anxiety symptoms, hyperactivity, suicidal ideation and behaviour and lifestyles such as substance abuse, including alcohol, smoking and illegal drugs; sleep, nutrition and physical activity, and Internet use is available and will be described during this presentation.
2584 – Comparison of Metabolic Syndrome Incidence Among Schizophrenia Patients Treated with Asenapine Versus Olanzapine
Authors: De Hert M. , Guiraud-Diawara A. , Marre C. 
Published: July 2013

Introduction:Atypical antipsychotics (AAPs) are known to increase the risk of metabolic syndrome (MetS), a predictor for cardiovascular disease and diabetes. This risk differs according to the AAPs.Objective:The objective of this analysis was to examine the incidence of MetS in schizophrenia patients treated with asenapine or olanzapine.Aim:The aim was to estimate the incidence of MetS among schizophrenia patients (DSM-IV criteria) after 52 weeks of exposure to asenapine or olanzapine.Methods:Pooled data from patients completing 52-week extension of randomized trials (041512, 041513, 25544 and A7501014) were included. Patients were treated with asenapine or olanzapine.The National Cholesterol Education Program, Adult Treatment Panel III (NCEP ATP III) definition of MetS was used, defined as 3 or more of the 5 following risk determinants: waist circumference > 102 cm for male and > 88 cm for female, triglycerides = 150 mg/dL, HDL cholesterol < 40 mg/dL for male and < 50 mg/dL for female, sitting blood pressure ≥ 130/85 mm Hg, or fasting glucose ≥ 110 mg/dL.Incidence (i.e. new metabolic cases in patients without MetS at baseline) was calculated at week 52.Results:741 patients were included in this analysis of 52-week studies (asenapine 397, olanzapine 344). After 52 weeks of treatment exposure, the incidence of MetS was significantly higher in olanzapine-treated patients than in asenapine-treated patients (19.44% versus 11.46%, p = 0.01).Conclusions:These post-hoc analyses confirmed a higher risk of developing a MetS with olanzapine. The incidence of MetS after 52 weeks of treatment with asenapine was found to be significantly lower.
2592 – Modality Shift Effect in Schizophrenia, Mania and Depression
Authors: Krag P.J. 
Published: July 2013

Introduction:The effect of a shift of sensory modality on the serial reaction times of patients with schizophrenia was first reported in 1961. Zubin & Spring (1977) argued that the modality shift effect (MSE) might be a vulnerability marker for schizophrenia. A MSE has, however, also been observed in patients with depression, brain damage, alcoholism etc.Objectives:To examine if patients with schizophrenia can be differentated from patients with mood disorder on the basis of the MSE to light and tone stimuli.Aims:To evaluate if MSE measures could be useful in the diagnostic process.Methods:58 patients with schizophrenia, 55 patients with mood disorder, and 30 healthy controls participated in a computerbased reaction time experiment. The stimuli were short visual and auditory signals presented in a randomized sequence. Participants were instructed to press a button each time they saw or heard a signal.Results:The MSE to both light and sound stimuli of the patients with schizophrenia and mood disorder was significantly longer than the control group’s. There was no significant difference in the patient groups’ MSE to light stimuli; but patients with schizophrenia had a significantly longer MSE to tone stimuli than patients with mood disorder. No clear or consistent differences were observed when comparing subgroups of schizophrenia patients with positive, mixed, and negative symptoms, and mood disorder patients in manic, neutral, and depressive phases.Conclusion:The MSE to visual and auditory stimuli is not specific for schizophrenia as it can also be observed in mood disorder.
2604 – The Ethnocultural Peculiarities of Suicides in Russia
Authors: Polozhy B. 
Published: July 2013

Introduction:According to the data of 2011, Russia is among the ten countries in the world with the highest suicide rate - 21.4 cases per 100 000 population. However, many aspects of the problem of suicide are not studied. This prevents the organization of the system of effective suicide prevention. in this regard special attention deserve ethnocultural factors, since they are essential to the moral and ethical attitude to the possibility of suicide and to potential willingness to formation of suicidal behavior.Objective:Study of the rate of suicide among different nations of Russia.Methods:Statistical analysis of suicide rate in the Russian Federation from 2005 to 2011.Results:The specificity of suicide situation in Russia is that suicide rates in different ethnic groups of the population has the distinction of reaching 30: from 3 per 100,000 in the Republic of Dagestan to 89.8 per 100,000 in the Nenets Autonomous District. This is due to cultural peculiarities of different ethnic groups, including the historically established their relationship to suicide.Taking in consideration this factors were elaborated the differential programs for suicide prevention. That has allowed to lower suicidal rate in average in 1.5 times for the last 7 years. That indicates the possible beneficial effects of the ethnocultural approach in suicide prevention strategies.Conclusion:In planning programs suicide prevention in multinational countries should take into account the ethnocultural characteristics of the residing peoples.
2612 – Inter-Relationship of the Functional Status Question of the PHQ-9 and Depression Remission After Six Months of Collaborative Care Management
Authors: Angstman K. 
Published: July 2013

Introduction:In collaborative care management (CCM) for depression, a restoration of premorbid functional status is as important as symptom reduction.Objectives:The goal of this study was to investigate if the baseline functional status of the patient (as determined by the tenth question of the PHQ-9) was an independent predictor of clinical outcomes six months after enrollment into CCM and the interdependence of clinical outcomes on functional improvement at six months.Methods:One thousand eighty three adult patients who were enrolled in CCM for the diagnosis of major depression or dysthymia and had a PHQ-9 score of 10 or greater were retrospectively reviewed.Results:Using a multiple regression model for clinical remission six months after enrollment into CCM; age, race and gender were not significant predictors of remission, however, being married was (OR 1.323 CI 1.013-1.727, P= 0.040). Patients in the Extremely Difficult category had an odds ratio of remission of 0.610 (CI 0.392-0.945, P=0.028) at six months compared to the Somewhat Difficult group. Also, the odds of a patient achieving normal functional status at six months was highly correlated to clinical remission (PHQ-9 < 5) with an odds ratio of 218.530 (p< 0.001).Conclusions:Depressed patients with worsening functional status at enrollment into CCM are less likely to achieve remission after six months, independent of all other variables studied. Also, improvement of a patient’s functional status at six months was highly correlated with clinical remission.
2639 – The Effectiveness of Agomelatine (Valdoxan) in the Treatment of Atypical Depression
Authors: Avedisova A. , Marachev M. 
Published: July 2013

Introduction:Treatment of atypical depression (AD) modern antidepressants poorly understood, whereas the study of AD in the context of chronobiological disorders necessitates selection pathogenetically substantiated therapy.Objectives:To determine the effectiveness of agomelatine in the treatment of AD.Aims:To compare the efficacy of agomelatine in patients with AD and melancholic depression (MD), the impact of the drug on the separate atypical symptoms, and the effect on AD in the first depressive episode (FDE), bipolar disorder (BD) and recurrent depressive disorder (RDD).Methods:6 week monotherapy agomelatine patients with AD (n=60, main group) and MD (n=30, control group) at a dose of 25 mg/day with the possibility of increasing to 50 mg/day. Used rating scales ADDS, BDI, HDRS-17, LSEQ, GAF.Results:Response rate of onset in the treatment of AD was higher (third week) than in the MD (fifth week). Reduction on a scale HDRS-17 was significant at the first week of treatment in both groups (p< 0,001). of atypical symptoms better than others were reduced hypersomnia and hyperphagia. Treatment of patients with AD at FDE, BD and RDD showed a higher percentage of responders at BD (82%) than in the RDD (64.2%) and especially (p < 0,01) for FDE (40%).Conclusions:Agomelatine has shown high efficacy in the treatment of AD (88.3%) and MD (83.3%), despite the opposite nature of the symptoms (insomnia and hypersomnia, decreased and increased appetite), as well as comparable efficacy in the treatment of AD in the structure as RDD and BD.
2648 – Having a Child With Autism: What Kind of Needs and Support Expectations for Parents?
Authors: Derguy C. , Bouvard M. , M’bailara K. , Denis Ferreira A. , Croisé A. , Michel G. 
Published: July 2013

Background:Raising a child with an autism spectrum disorder (ASD) is a daily stressful experience implying changes in family functioning [1]. Parents are more likely to experience psychological and educational difficulties and their vulnerability is clearly described [2, 3]. Most studies deal with parental difficulties (medical, psychological…) whereas those focusing on parental self-reported support needs, related to ASD are lacking.Objectives:The aim of this study was to investigate parents’ needs and their support expectations in order to investigate needs priority.Methods:Two parents groups of children aged between 3 and 10 years are compared (ASD or control group). Mothers and fathers were interviewed about unmet needs using The Parental Needs Questionnaire, developed for this study and semistructured interview used to evaluate parents’ needs in terms of quality.Results:141 parents were included, 57 with an ASD child and 84 with TD children. There are 6 need areas for ASD child parents as well as controls: materials, time management, information, education, psychological support and relational difficulties. Parents of ASD child describe priority information needs (89.5%), psychological (73.5%), material needs (71%) and education (58.5%). These needs are listed last in the control group (respectively 10.5%, 26.5%, 29%, and 41.5%).Conclusions:Providing parental assistance should be based on three key dimensions to receive specific information, to have psychological and social support and to manage child disorder. in practice today only the third axis is often considered in programs [4]. So, we make relevant recommendations about support for parents of ASD child.
2653 – Influence of Polymorphisms in Genes SLC1A1, GRIN2B and GRIK2 On Clozapine-Induced Obsessive-Compulsive Symptoms
Authors: Zhang C. 
Published: July 2013

Objectives:Clinical observations indicate that atypical antipsychotics, especially clozapine, induce obsessive-compulsive (OC) symptoms in schizophrenic patients. Recent data from neuroimaging and clinical trials suggest a role for altered glutamate neurotransmission in the etiology of OCD. It has been reported that SLC1A1, GRIN2B and GRIK2 regulate glutamate transmission and affect OCD pathophysiology. This study aimed to determine whether SLC1A1, GRIN2B and GRIK2 are associated with clozapine-induced OC symptoms.Methods:A total of 250 clinically stable schizophrenic patients receiving clozapine treatment and 261 sex- and age-matched controls were recruited. The Yale-Brown Obsessive Compulsive Scale (Y-BOCS) was used to evaluate the severity of OC symptoms. Based on the Y-BOCS score, 250 patients were divided into OC group and non-OC group (patients with and without OC symptoms, respectively). Three reported OCD susceptibility polymorphisms SLC1A1 (rs2228622), GRIN2B (rs890) and GRIK2 (rs1556995) were genotyped.Results:Trends of association with OC symptoms were observed in rs2228622A and rs890T alleles. SLC1A1 and GRIN2B interaction was found in the significant 2-locus, gene-gene interaction model (P=0.0021), using a MDR method. Further analysis showed a significant interaction between SLC1A1 and GRIN2B on the Y-BOCS score (F6, 137=7.650, P 0.001), and individuals with AA/TT genotypes had a significantly higher mean Y-BOCS score than those with other genotypes, except AG/TT.Conclusions:These results suggest that SLC1A1, GRIN2B and interactions between the two might confer a susceptibility to OC symptoms in schizophrenic patients receiving clozapine.
2659 – The Alternating Only-Tact Training and Mand-Tact Training in the Acquisition of Tacts in a Child with Mental Retardation
Authors: Luccherino L. , Scali V. 
Published: July 2013

Introduction:The studies of Carroll e Hesse (1987) and the studies of Arntzen e Almas (2002) demonstrate the effectiveness of mand-tact training rather than only tact training on the expansion of the tact repertoire in groups of children with developmental disabilities.Objectives:The authors want to show the effectiveness of mand-tact training rather than only tact training on the expansion of the tact repertoire in a child with moderate mental retardation.Method:In the present work, we conducted an assessment pre-training in which the baseline data of the tact in the child's repertorie was collected, with an assessment choice preference to identify the reinforcers to use in the training. in the training, sessions only-tact training and sessions mand-tact training are alternated, according to the principles and procedures of Applied Behavior Analysis (ABA).Results:The results obtained show that the mand-tact training is more effective than the only-tact training in the rapid acquisition of tacts.Conclusions:The mand contingiences represent a facilitation in the acquisition of the tact repertoire.