bluuebunny/crossref_metadata_2025_split huggingface dataset:
Facet‐Dependent Catalytic Activity of Cu2O Nanocrystals in the One‐Pot Synthesis of 1,2,3‐Triazoles by Multicomponent Click Reactions
Authors: Chanda Kaushik , Rej Sourav , Huang Michael H. 
Published: October 2013

AbstractWe report the highly facet‐dependent catalytic activity of Cu2O nanocubes, octahedra, and rhombic dodecahedra for the multicomponent direct synthesis of 1,2,3‐triazoles from the reaction of alkynes, organic halides, and NaN3. The catalytic activities of clean surfactant‐removed Cu2O nanocrystals with the same total surface area were compared. Rhombic dodecahedral Cu2O nanocrystals bounded by {110} facets were much more catalytically active than Cu2O octahedra exposing {111} facets, whereas Cu2O nanocubes displayed the slowest catalytic activity. The superior catalytic activity of Cu2O rhombic dodecahedra is attributed to the fully exposed surface Cu atoms on the {110} facet. A large series of 1,4‐disubstituted 1,2,3‐triazoles have been synthesized in excellent yields with high regioselectivity under green conditions by using these rhombic dodecahedral Cu2O catalysts, including the synthesis of rufinamide, an antiepileptic drug, demonstrating the potential of these nanocrystals as promising heterogeneous catalysts for other important coupling reactions.
Realistic Energy Surfaces for Real‐World Systems: An IMOMO CCSD(T):DFT Scheme for Rhodium‐Catalyzed Hydroformylation with the 6‐DPPon Ligand
Authors: Gellrich Urs , Himmel Daniel , Meuwly Markus , Breit Bernhard 
Published: October 2013

AbstractThe hydroformylation of terminal alkenes is one of the most important homogeneously catalyzed processes in industry, and the atomistic understanding of this reaction has attracted enormous interest in the past. Herein, the whole catalytic cycle for rhodium‐catalyzed hydroformylation with the 6‐diphenylphosphinopyridine‐(2H)‐1‐one (6‐DPPon) ligand 1 was studied. This catalytic transformation is challenging to describe computationally, since two requirements must be met: 1) changes in the hydrogen‐bond network must be modeled accurately and 2) bond‐formation/bond‐breaking processes in the coordination sphere of the rhodium center must be calculated accurately. Depending on the functionals used (BP86, B3LYP), the results were found to differ strongly. Therefore, the complete cycle was calculated by using highly accurate CCSD(T) computations for a PH3 model ligand. By applying an integrated molecular orbital plus molecular orbital (IMOMO) method consisting of CCSD(T) as high level and DFT as low‐level method, excellent agreement between the two functionals was achieved. To further test the reliability of the calculations, the energetic‐span model was used to compare experimentally derived and computed activation barriers. The accuracy of the new IMOMO method apparently makes it possible to predict the catalytic potential of real‐world systems.
The Synthesis of Methylated, Phosphorylated, and Phosphonated 3′‐Aminoacyl‐tRNASec Mimics
Authors: Rigger Lukas , Schmidt Rachel L. , Holman Kaitlyn M. , Simonović Miljan , Micura Ronald 
Published: October 2013

AbstractThe twenty first amino acid, selenocysteine (Sec), is the only amino acid that is synthesized on its cognate transfer RNA (tRNASec) in all domains of life. The multistep pathway involves O‐phosphoseryl‐tRNA:selenocysteinyl‐tRNA synthase (SepSecS), an enzyme that catalyzes the terminal chemical reaction during which the phosphoseryl–tRNASec intermediate is converted into selenocysteinyl‐tRNASec. The SepSecS architecture and the mode of tRNASec recognition have been recently determined at atomic resolution. The crystal structure provided valuable insights that gave rise to mechanistic proposals that could not be validated because of the lack of appropriate molecular probes. To further improve our understanding of the mechanism of the biosynthesis of selenocysteine in general and the mechanism of SepSecS in particular, stable tRNASec substrates carrying aminoacyl moieties that mimic particular reaction intermediates are needed. Here, we report on the accurate synthesis of methylated, phosphorylated, and phosphonated serinyl‐derived tRNASec mimics that contain a hydrolysis‐resistant ribose 3′‐amide linkage instead of the natural ester bond. The procedures introduced allow for efficient site‐specific methylation and/or phosphorylation directly on the solid support utilized in the automated RNA synthesis. For the preparation of (S)‐2‐amino‐4‐phosphonobutyric acid–oligoribonucleotide conjugates, a separate solid support was generated. Furthermore, we developed a three‐strand enzymatic ligation protocol to obtain the corresponding full‐length tRNASec derivatives. Finally, we developed an electrophoretic mobility shift assay (EMSA) for rapid, qualitative characterization of the SepSecS‐tRNA interactions. The novel tRNASec mimics are promising candidates for further elucidation of the biosynthesis of selenocysteine by X‐ray crystallography and other biochemical approaches, and could be attractive for similar studies on other tRNA‐dependent enzymes.
Arene CH Amination at Nickel in Terphenyl–Diphosphine Complexes with Labile Metal–Arene Interactions
Authors: Herbert David E. , Lara Nadia C. , Agapie Theodor 
Published: October 2013

AbstractThe meta‐terphenyl diphosphine, m‐P2, 1, was utilized to support Ni centers in the oxidation states 0, I, and II. A series of complexes bearing different substituents or ligands at Ni was prepared to investigate the dependence of metal–arene interactions on oxidation state and substitution at the metal center. Complex (m‐P2)Ni (2) shows strong Ni0–arene interactions involving the central arene ring of the terphenyl ligand both in solution and the solid state. These interactions are significantly less pronounced in Ni0 complexes bearing L‐type ligands (2‐L: L=CH3CN, CO, Ph2CN2), NiIX complexes (3‐X: X=Cl, BF4, N3, N3B(C6F5)3), and [(m‐P2)NiIICl2] (4). Complex 2 reacts with substrates, such as diphenyldiazoalkane, sulfur ylides (Ph2SCH2), organoazides (RN3: R=para‐C6H4OMe, para‐C6H4CF3, 1‐adamantyl), and N2O with the locus of observed reactivity dependent on the nature of the substrate. These reactions led to isolation of an η1‐diphenyldiazoalkane adduct (2‐Ph2CN2), methylidene insertion into a NiP bond followed by rearrangement of a nickel‐bound phosphorus ylide (5) to a benzylphosphine (6), Staudinger oxidation of the phosphine arms, and metal‐mediated nitrene insertion into an arene CH bond of 1, all derived from the same compound (2). Hydrogen‐atom abstraction from a NiI–amide (9) and the resulting nitrene transfer supports the viability of Ni–imide intermediates in the reaction of 1 with 1‐azido‐arenes.
ChemInform Abstract: Light‐Induced Structural Changes in (HgBr2)3(As4S4)2: An X‐Ray Single‐Crystal Diffraction, Raman Spectroscopy and ab initio Study.
Authors: Zoppi M. , Bindi L. , Roedl T. , Pielnhofer F. , Weihrich R. , Pfitzner A. , Bonazzi P. 
Published: October 2013

AbstractThe response to light exposure of the As4S4 molecule within the structure of (HgBr2)3(As4S4)2 (space group P21/c, Z = 2) is investigated by single crystal XRD, Raman spectroscopy, and relativistic DFT‐GGA band structure calculations.
ChemInform Abstract: Bonding Preference of Carbon, Nitrogen, and Oxygen in Niobium‐Based Rock‐Salt Structures.
Authors: Miura Akira , Takei Takahiro , Kumada Nobuhiro , Wada Satoshi , Magome Eisuke , Moriyoshi Chikako , Kuroiwa Yoshihiro 
Published: October 2013

AbstractThe effect of carbon, nitrogen, and oxygen on rock‐salt‐based NbX (X: C, N, O) is investigated by TB‐LMTO‐ASA calculations and synchrotron powder XRD.
ChemInform Abstract: Synthesis, Crystal Structure and Luminescence Properties of CaY2‐xEuxGe3O10 (x = 0—2).
Authors: Lipina Olga A. , Surat Ludmila L. , Melkozerova Marina A. , Tyutyunnik Alexander P. , Leonidov Ivan I. , Zubkov Vladimir G. 
Published: October 2013

AbstractThe red emitting title phosphors are prepared by solid state reaction of stoichiometric mixtures of Y2O3, Eu2O3, CaCO3, and GeO2 (1250 °C, 72 h) and by an EDTA‐complexing process from nitric acid solutions of Y2O3, Eu2O3, and CaCO3, EDTA, and ammonia solutions of GeO2 (annealing at 1100 °C, 6 h).
ChemInform Abstract: Structural and Luminescence Characteristics of Sr3Al8SiO17:Eu2+ Nanophosphor.
Authors: Kumar Ashwini , Dhoble S. J. , Peshwe D. R. , Bhatt Jatin 
Published: October 2013

AbstractThe title phosphor is synthesized from stoichiometric mixtures of Sr(NO3)2, Al(NO3)3, SiO2, Eu2O3 dissolved in HNO3, and urea preheated to 600 °C, followed by spontaneous ignition and combustion.
ChemInform Abstract: Synthesis and Microwave Dielectric Properties of B2O3‐Doped Mg2GeO4 Ceramics.
Authors: Chen C. X. , Wu S. P. , Fan Y. X. 
Published: October 2013

AbstractThe title ceramics are synthesized by solid state reaction of MgO nanoparticles, GeO2, and B2O3 milled with zirconia balls for 8 h followed by calcination at 1000 °C for 6 h and sintering at 1050—1300 °C for 4 h.
ChemInform Abstract: An Advanced Selenium—Carbon Cathode for Rechargeable Lithium—Selenium Batteries.
Authors: Yang Chun‐Peng , Xin Sen , Yin Ya‐Xia , Ye Huan , Zhang Juan , Guo Yu‐Guo 
Published: October 2013

AbstractSelenium is confined as cyclic Se8 molecules in the mesopores of an ordered mesoporous carbon (CMK‐3) matrix by a melt‐diffusion process from a ball‐milled mixture of CMK‐3 and Se (autoclave, Ar, 260 °C, 12 h).
ChemInform Abstract: Bioinspired Synthesis of ZnS Supraparticles Toward Photoinduced Dechlorination of 2,2′,4,4′,5,5′‐Hexachlorobiphenyl.
Authors: He Liangcan , Xiong Yansong , Zhao Meiting , Mao Xiang , Liu Yaling , Zhao Huijun , Tang Zhiyong 
Published: October 2013

AbstractZnS supraparticles are prepared from aqueous solutions of Zn(ClO4)2, L‐cysteine, and NaOH (37 °C, 4 weeks).
ChemInform Abstract: Ni‐Catalyzed Cascade Cyclization—Kumada Alkyl—Alkyl Cross‐Coupling.
Authors: Guisan‐Ceinos Manuel , Soler‐Yanes Rita , Collado‐Sanz Daniel , Phapale Vilas B. , Bunuel Elena , Cardenas Diego J. 
Published: October 2013

AbstractA powerful Ni‐catalyzed cascade reaction involving cyclization followed by cross‐coupling allows the formation of up to three alkyl—alkyl bonds in a single operation by using alkene‐containing alkyl iodides and Grignard reagents.
ChemInform Abstract: N‐Acyl‐ and N‐Sulfonylformamidines from Cyanamides and Carbodiimides by Hydroalumination and Subsequent Treatment with Electrophiles.
Authors: Hellmann Johannes , Rhotert Ines , Westenberg Hauke , Froehlich Roland , Wibbeling Birgit , Uhl Werner , Wuerthwein Ernst‐Ulrich 
Published: October 2013

AbstractThe synthetic potential of hydroalumination reactions of cyanamides and carbodiimides is demonstrated.
ChemInform Abstract: Synthesis of Previously Unknown 3,3′‐Linearly Linked Sulfur‐ and Selenium‐Containing Bispyrazoles by Reactions of 3‐Alkenyl‐5‐chloropyrazoles with Bischalcogenols.
Authors: Rudyakova E. V. , Samultsev D. O. , Levanova E. P. , Levkovskaya G. G. 
Published: October 2013

AbstractThis method yields anti‐Markovnikov products.
ChemInform Abstract: Enantioselective Construction of α‐Quaternary Cyclobutanones by Catalytic Asymmetric Allylic Alkylation.
Authors: Reeves Corey M. , Eidamshaus Christian , Kim Jimin , Stoltz Brian M. 
Published: October 2013

AbstractThe first transition metal‐catalyzed enantioselective α‐alkylation of cyclobutanes (I) and (III) to give α‐quarternary cyclobutanones by using a Pd‐catalyst in the presence of a PHOX‐type ligand is developed.
ChemInform Abstract: Stereoselective Synthesis of 1‐Methyl‐1,2‐ and 1,3‐Cyclopentanediols via γ‐Lactones.
Authors: Niidu A. , Paju A. , Mueuerisepp A.‐M. , Jaerving I. , Kailas T. , Pehk T. , Lopp M. 
Published: October 2013

AbstractThe synthesis of title compounds (VIII)/(IX) and (XIV)/(XV) is described.
ChemInform Abstract: Azulenophenanthrenes from 2,2′‐Di(arylethynyl)biphenyls Through C—C Bond Cleavage of a Benzene Ring.
Authors: Matsuda Takanori , Goya Tsuyoshi , Liu Lantao , Sakurai Yusuke , Watanuki Shoichi , Ishida Naoki , Murakami Masahiro 
Published: October 2013

AbstractA novel Pt‐catalyzed rearrangement reaction of biphenyls (I) is developed to form azulene derivatives by structural reorganization between the ethyne and arylethyne moieties.
ChemInform Abstract: A Convenient Synthesis of γ‐Amino‐ynamides via Additions of Lithiated Ynamides to Aryl Imines; Observation of an Aza‐Meyer—Schuster Rearrangement.
Authors: Tang Yu , et al. et al. 
Published: October 2013

AbstractThe synthesis of γ‐amino‐ynamides via nucleophilic addition of lithiated ynamides to aryl amines is developed and the use of the products in subsequent derivatization reactions is demonstrated.
ChemInform Abstract: Molecular Iodine Catalyzed Transfer Hydrogenation: Reduction of Aldimines, Ketimines, and α‐Imino Esters.
Authors: Bachu Prabhakar , Zhu Chen , Akiyama Takahiko 
Published: October 2013

AbstractA facile protocol using molecular iodine as the catalyst and Hantzsch ester as hydrogen source allows the conversion of aldimines, ketimines and α‐imino esters into the corresponding amines under mild reaction conditions.
ChemInform Abstract: Enantio‐ and Diastereodivergent Dual Catalysis: α‐Allylation of Branched Aldehydes.
Authors: Krautwald Simon , Sarlah David , Schafroth Michael A. , Carreira Erick M. 
Published: October 2013

AbstractThe presented dual‐catalytic synthesis discloses an access to γ,δ‐unsaturated aldehydes with two vicinal, asymmetric carbon atoms.
ChemInform Abstract: Convenient and Eco‐Friendly Method for the Conversion of Benzylic Alcohols into Aldehydes, Ketones, and Carboxylic Acids Using NaOCl Without Any Additives in 1,2‐Dimethoxyethane.
Authors: Fukuda Naohiro , Kajiwara Takeshi , Katou Tomoaki , Majima Keisuke , Ikemoto Tomomi 
Published: October 2013

AbstractA simple procedure allows oxidation of benzylic alcohols to aldehydes and ketones.
ChemInform Abstract: Mg(ClO4)2 Catalyzed Preparation of 1‐Amidoalkyl‐2‐naphthols under Solvent‐Free Conditions.
Authors: Amrollahi Mohammad Ali , Mirjalili Bi Bi Fatemeh , Emtiazi Hamideh 
Published: October 2013

AbstractThe title compounds are efficiently obtained by this new three‐component, one‐pot reaction of 2‐naphthol or phenol, various aldehydes (II) and amines (III).
ChemInform Abstract: Copper‐Catalyzed C—N Cross‐Coupling of Substituted 2‐Halobenzoates with Secondary Acyclic Amides.
Authors: Wang Man‐Gang , Yu Hua , Wu Jun , Shang Zhi‐Cai 
Published: October 2013

AbstractCopper‐catalyzed cross‐coupling reactions of secondary amides with alkyl 2‐iodobenzoates give hindered tertiary amides.
ChemInform Abstract: Rhodium(I)‐Catalyzed N—CN Bond Cleavage: Intramolecular β‐Cyanation of Styrenes.
Authors: Wang Rui , Falck John R. 
Published: October 2013

AbstractThe first examples of an intramolecular cyanation of styrene derivatives via a Rh‐Catalyzed N—CN cleavage reaction are given.
ChemInform Abstract: Alcohol Assisted C—C Bond Breaking: Copper‐Catalyzed Deacetylative α‐Arylation of β‐Keto Esters and Amides
Authors: Ke Jie , He Chuan , Liu Huiying , Xu Huan , Lei Aiwen 
Published: October 2013

Abstractleading to β‐aryl esters and amides
ChemInform Abstract: Enantioselective Catalytic Synthesis of Ethyl Mandelate Derivatives Using Rh(I)—NHC Catalysts and Organoboron Reagents.
Authors: Marques Carolina S. , Burke Anthony J. 
Published: October 2013

AbstractThe arylation of ethyl glyoxalate in the presence of chiral Rh(I)‐NHC catalysts provides ethyl mandelate derivatives with very low enantioselectivities.
ChemInform Abstract: Sulfur(IV)‐Mediated Transformations: From Ylide Transfer to Metal‐Free Arylation of Carbonyl Compounds.
Authors: Huang Xueliang , Patil Mehendra , Fares Christophe , Thiel Walter , Maulide Nuno 
Published: October 2013

AbstractDifferent reaction pathways are revealed in the reactions with Martin′s sulfurane (II) or other sulfur(IV)‐reagents, generated in situ from sulfoxides, depending on the counter ions.
ChemInform Abstract: Transition‐Metal‐Free Direct Arylation: Synthesis of Halogenated 2‐Amino‐2′‐hydroxy‐1,1′‐biaryls and Mechanism by DFT Calculations.
Authors: Gao Hongyin , Ess Daniel H. , Yousufuddin Muhammed , Kuerti Laszlo 
Published: October 2013

AbstractThe reaction proceeds with complete regioselectivity to afford the target compounds, which are difficult to prepare using other methods.
ChemInform Abstract: Chiral Sulfinamide‐Olefin Ligands: Switchable Selectivity in Rhodium‐Catalyzed Asymmetric 1,2‐Addition of Arylboronic Acids to Aliphatic α‐Ketoesters.
Authors: Zhu Ting‐Shun , Xu Ming‐Hua 
Published: October 2013

AbstractThe easy and practical title synthesis affords a variety of optically active tertiary α‐hydroxyesters.
ChemInform Abstract: Facile Access to Chiral Alcohols with Pharmaceutical Relevance Using a Ketoreductase Newly Mined from Pichia guilliermondii.
Authors: Xu Guochao , Yu Huilei , Xu Jianhe 
Published: October 2013

AbstractThe enantioselective reduction of ketones and 3‐keto esters is presented employing a newly mined carbonyl reductase from P.
ChemInform Abstract: C—H Activation Route to Dibenzo[a,e]pentalenes: Annulation of Arylacetylenes Promoted by PdCl2—AgOTf‐o‐Chloranyl.
Authors: Maekawa Takehisa , Segawa Yasutomo , Itami Kenichiro 
Published: October 2013

AbstractThis novel annulation of arylacetylenes proceeds through ortho‐selective electrophilic C‐H palladation initiated by alkyne‐palladium precoordination.
ChemInform Abstract: Silica‐Supported Ionic Liquid as Highly Efficient Catalyst for One‐Pot Synthesis of Acenaphtho[1,2‐b]furan Compounds.
Authors: Sandaroos Reza , Goldani Mohammad Taghi , Damavandi Saman 
Published: October 2013

AbstractThe title compounds (IV) are efficiently obtained from (acenaphthylen‐1‐yloxy)trimethylsilane (I), various aldehydes and isocyanides.
ChemInform Abstract: Organocatalytic Michael Addition of Malonates to Isatylidene‐3‐acetaldehydes: Application to the Total Synthesis of (—)‐Debromoflustramine E.
Authors: Liu Renrong , Zhang Junliang 
Published: October 2013

Abstract(‐)‐Debromoflustramine E (X) is obtained in 29% overall yield.
ChemInform Abstract: Furan Ring Opening‐Pyrrole Ring Closure. A Simple Route to 1,2,3,4‐Tetrahydropyrrolo[1,2‐a]pyrazin‐3‐ones.
Authors: Trushkov Igor V. , Nevolina Tatyana A. , Shcherbinin Vitaly A. , Sorotskaya Lyudmila N. , Butin Alexander V. 
Published: October 2013

AbstractA simple and efficient approach to convert furfurylamines into the title compounds (IV) via acylation, deprotection, furan ring opening, and Paal—Knorr cyclization sequence is developed.
ChemInform Abstract: New and Rapid Access to Synthesis of Novel Polysubstituted Imidazoles Using Antimony Trichloride and Stannous Chloride Dihydrate as Effective and Reusable Catalysts.
Authors: Poorali Leyla , Karami Bahador , Eskandari Khalil , Azizi Mahboobeh 
Published: October 2013

AbstractA new and efficient and environmentally benign synthesis of the title compounds (IV),(VI) by multicomponent reaction of various aldehydes, benzil, aliphatic and aromatic primary amines and ammonium acetate under solvent‐free conditions is presented.
ChemInform Abstract: A Simple and Convenient Two‐Step, One‐Pot Synthesis of Heteroimidazoles from Nitroaminoaryls Catalyzed by Ytterbium Triflate.
Authors: Wang Fen , Tran‐Dube Michelle , Scales Stephanie , Johnson Sarah , McAlpine Indrawan , Ninkovic Sacha 
Published: October 2013

AbstractAn efficient two‐step, one‐pot conversion of o‐nitroamino aromatics, e.g. (I), (IV), (VII), (VIII), (X), and (XII) into corresponding benzo‐ and heteroaromatic fused imidazoles is described.
ChemInform Abstract: A New Class of Multi‐Substituted Oxazole Derivatives: Synthesis and Antimicrobial Activity.
Authors: Reddy A. Babul , Hymavathi R. V. , Swamy G. Narayana 
Published: October 2013

AbstractMulti‐substituted oxazole derivatives containing a heterocyclic moiety (20 examples) are efficiently obtained from various aldehydes.
ChemInform Abstract: Copper Salt of 12‐Tungstophosphoric Acid: An Efficient and Reusable Heteropoly Acid for the Click Chemistry.
Authors: Purnima K. V. , Sreenu D. , Bhasker N. , Nagaiah K. , Lingaiah N. , Reddy B. V. Subba , Yadav J. S. 
Published: October 2013

AbstractThe catalyst can be recovered and reused for three to four subsequent runs with a minimal decrease of activity.
ChemInform Abstract: Synthesis of Polyalkoxy‐3‐(4‐methoxyphenyl)coumarins with Antimitotic Activity from Plant Allylpolyalkoxybenzenes.
Authors: Tsyganov Dmitry V. , Chernysheva Natalia B. , Salamandra Lev K. , Konyushkin Leonid D. , Atamanenko Olga P. , Semenova Marina N. , Semenov Victor V. 
Published: October 2013

AbstractCoumarins, analogues of natural antimitotic compounds, are synthesized and tested in vivo in the phenotypic sea urchin embryo assay for antiproliferative antitubulin activity.
ChemInform Abstract: A Practical Protocol for Three‐Component, One‐Pot, Stepwise Sonogashira—Heterocyclization—Heck Couplings.
Authors: Madich Youssef , Denis J. Gabriel , Ortega Aitor , Martinez Claudio , Matrane Abdellatif , Belachemi Larbi , de Lera Angel R. , Alvarez Rosana , Aurrecoechea Jose M. 
Published: October 2013

AbstractA stepwise protocol is developed for the three‐component process using halobenzamides, alkynes, and ethyl acrylate.
ChemInform Abstract: Synthesis of New Isolated and Fused Tri‐ and Tetracyclic Pyridine Derivatives.
Authors: El‐Essawy F. A. , El‐Sayed W. A. , El‐Etrawy A. Sh. , El‐Bayaa M. N. 
Published: October 2013

AbstractCompounds (I) and (XI) are used as starting materials for the syntheses of a variety of heterocyclic compounds such as (X), (XV), (XVI), (XVIII), (XIX), (XXI), and (XXII).
ChemInform Abstract: L‐Proline‐Catalyzed Synthesis of Functionalized Unsymmetrical Dihydro‐1H‐indeno[1,2‐b]pyridines.
Authors: Behbahani Farahnaz Kargar , Alaei Hourieh Sadat 
Published: October 2013

AbstractTitle compounds are obtained by a new one‐pot, four‐component reaction of aromatic aldehydes, ethyl acetoacetate, 1,3‐indandione, and ammonium acetate using L‐proline as catalyst in water.
ChemInform Abstract: Synthesis of 1,4‐Disubstituted Pyrazolo[3,4‐d]pyrimidines from 4,6‐Dichloropyrimidine‐5‐carboxaldehyde: Insights into Selectivity and Reactivity.
Authors: Morrill Christie , Babu Suresh , Almstead Neil G. , Moon Young‐Choon 
Published: October 2013

AbstractThe reactions of 4,6‐dichloropyrimidine‐5‐carbaldehyde with aromatic and aliphatic hydrazines are developed.
ChemInform Abstract: Synthesis of Novel Bis(pyrimido[5,4‐c]quinoline‐2,4(1H,3H)‐dione) and Its Derivatives: Evaluation of Their Antioxidant Properties.
Authors: Parameswaran Kandasamy , Sivaguru Paramasivam , Lalitha Appaswami 
Published: October 2013

AbstractThe title compounds (IV),(VI) are obtained in an one‐pot cyclocondensation reaction of barbituric/thiobarbituric acid with aromatic aldehydes and p‐phenylenediamine/2,6‐diaminopyridine.
ChemInform Abstract: A Practical, Ligand‐Free, Palladium‐Catalyzed Isocyanide Insertion Reaction for the Construction of Novel Ring‐Fused Quinazolines.
Authors: Ji Fei , Lv Mei‐fang , Yi Wen‐bin , Cai Chun 
Published: October 2013

AbstractA cascade reaction of isatoic anhydride, phenylhydrazines and 2‐bromobenzaldehyde provides the key intermediates (IV) which undergo Pd‐catalyzed isocyanide insertion reactions to afford novel ring‐fused quinazolines.
ChemInform Abstract: Synthesis of Novel 1‐Alkyl‐1,2‐dihydro‐2‐imino‐4‐quinazolinamines by Tandem Reaction of the Three Components.
Authors: Guo Zhen , Yin Ping , He Ling , Qi Qing Rong 
Published: October 2013

AbstractA novel and efficient synthesis of quinazoline derivatives is developed involving Cu‐Catalyzed Ullmann‐type coupling of o‐bromo‐substituted N‐cyanobenzenecarboximidates and subsequent intramolecular cyclization reactions.
ChemInform Abstract: Gold(I)‐Catalyzed Cascade Cycloadditions Between Allenamides and Carbonyl‐Tethered Alkenes: An Enantioselective Approach to Oxa‐Bridged Medium‐Sized Carbocycles.
Authors: Faustino Helio , Alonso Isaac , Mascarenas Jose L. , Lopez Fernando 
Published: October 2013

AbstractA simple cascade cycloaddition of allenamides such as (II) with carbonyl‐tethered alkenes is discovered to open an access to oxo‐bridged seven to nine‐membered cycloalkanes having an exocyclic enamide moiety.