bluuebunny/crossref_metadata_2025_split huggingface dataset:
2821 – Dopamine D2/3 Receptor Availability and Human Cognitive Impulsivity: A High-Resolution Pet Imaging Study with [11C]Raclopride
Authors: Kim J.-H. , Son Y.-D. , Kim H.-K. , Lee S.-Y. , Kim Y.-B. , Cho Z.-H. 
Published: July 2013

Introduction and objectives:: Human impulsivity is a complex multidimensional construct encompassing cognitive, emotional, and behavioral aspects. Previous animal studies have suggested that striatal dopamine receptors play a critical role in impulsivity. in this study, we investigated the relationship between self-reported cognitive impulsiveness and dopamine D2/3 receptor availability in striatal subdivisions in healthy subjects using high-resolution positron emission tomography (PET) with [11C]raclopride.Methods:Twenty-one participants completed 3-Tesla magnetic resonance imaging and high-resolution PET scans with [11C]raclopride. The trait of impulsiveness was measured using the Barratt Impulsiveness Scale (BIS-11). Partial correlation analysis was performed between BIS-11 scores and D2/3 receptor availability in striatal subregions, controlling for the confounding effects of temperament characteristics that are conceptually or empirically related to dopamine, which were measured by the Temperament and Character Inventory.Results:The analysis revealed that the non-planning (p = 0.004) and attentional (p = 0.007) impulsiveness subscale scores on the BIS-11 had significant positive correlations with D2/3 receptor availability in the pre-commissural dorsal caudate. There was a tendency toward positive correlation between non-planning impulsiveness score and D2/3 receptor availability in the post-commissural caudate.Conclusions:These results suggest that cognitive subtrait of impulsivity is associated with D2/3 receptor availability in the associative striatum that plays a critical role in cognitive processes involving attention to detail, judgment of alternative outcomes, and inhibitory control.
2822 – Impulsivity and Attention Deficit-Hyperactivity Symptoms Among Female Patients with Obesity
Authors: Karaahmet E. , Altinbas K. , Sen H. , Gunes F. , Bakim B. , Konuk N. 
Published: July 2013

Aim:The relationship between obesity and Attention Deficit-Hyperactivity Disorder(ADHD) has been studied in recent years. It was indicated that the proportion of ADHD in children with obesity was high and body mass index (BMI) of children with ADHD was also higher than healthy controls [1]. Impulsivity as a trait was found to be associated with obesity and predictor of future weight gain among children with obesity (2,3). From here, we aim to evaluate the impulsivity and ADHD symptoms among adults with obesity.Methods:32 female patients with obesity (BMI>30) who admitted to the diet clinic of Çanakkale Onsekiz Mart University Medical Faculty were recruited for the study. ADHD symptoms were evaluated with Wender Utah Rating Scale(WURS) while impulsivity was measured with Barratt Impulsiveness Scale(BIS).Results:Mean age, BMI, WURS and BIS scores of the patiens were 35.3 ± 10.8 years, 39.2 ± 6.2 kg., 35.8 ± 19.2 and 61.3 ± 10.4, respectively. 42.3% of the patiens had child and adolescent ADHD symptoms and one third still had ADHD symptoms in adulthood (12.5% inattentive, 9.4% hyperactive-impulsive, 6.2% combined). BIS total(p+0.003), BIS attention(p < 0.01) and self control(p = 0.004) sub-item scores were positively correlated with WURS total scores.Discussion:Our findings were consistent the literature that patients with obesity were more impulsive than healthy controls(4).Conclusion:ADHD and impulsivity might have implications for weight regulation. Our findings may provide a frame work for future studies with bigger sample sizes aiming to detect the relationship between impulsivity and ADHD symptoms in patients with obesity.
2854 – Depression, Anxiety and Anger in Patients with Polycystic Ovary Syndrome
Authors: Erdem M. , Balikci A. , Keskin U. , Bozkurt Zincir S. , Gülsün M. , Özçelik F. , Akgül E.Ö. , Akarsu S. , Öztosun M. , Ergün A. 
Published: July 2013

Introduction:PCOS is a syndrome of the heterogeneous nature, affecting multiple systems, particularly the endocrine system. We propose to investigate the possible relationships among hormonal changes, levels of anxiety, depression, and anger in patients with PCOS.Method:Fourty four female patients with PCOS and 44 BMI (Body Mass Index)-matched healthy women participated in this study. We measured the sociodemographic features, some serum hormonal levels (insulin, gonadotropins, prolactin, dehydroepiandrosterone sulfate (DHEAS), TSH, T3, T4, 17 OH-Progesterone, total and free testosterone) and some other biochemical parameters of the participants. Also, all participants completed Trait Anger-Anger Expression Scale (STAS), Beck Depression and Beck Anxiety Inventories.Results:The mean ages of the patients with PCOS and control subjects were 27.3 ± 5.6 and 27.4 ± 6.1 years, respectively. The measures of BMI, insulin, LH, DHEAS, and total testosterone serum levels in the patient group were significantly higher than the control group (p < 0.05). There was statistically significant positive correlation between BAI scores and DHEAS levels. We found significant differences between two groups in terms of trait anger, anger control, anger outward and inward, anxiety level and depression scores (P < 0.05).Conclusion:Anxiety symptoms indicate stronger relationship compared to the depression with the DHEAS serum levels via autonomic nervous system, considering GABA antagonistic effect of DHEAS. Obesity, hirsutism, and infertility may reduce selfconfidence, and create depressive symptoms in patients with PCOS. in addition, changes in the hormonal levels may lead to anxiety directly. Possibly, depressive symptoms are a secondary reflection of these changes.
2856 – Tramadol Dependence in a Patient with no Previous Substance History
Authors: Ben Ammar H. , Jomli R. , Rihab E. , Moula O. , Bouasker A. , Ghachem R. 
Published: July 2013

Introduction:Tramadol, initially introduced in Germany in 1977, is a synthetic analgesic and appears to have a dual mechanism of action; a weak μ-opioid receptor agonism and a reuptake inhibition of serotonin and noradrenaline. It is marketed in Tunisia since 2001. Generally, Tramadol is considered to have a very low risk of dependence and abuse, but rare cases of tramadol dependence have been described in patients without prior substance abuse history. We describe one such case in a relatively young, otherwise healthy patient.Case report:Mr AR, a 47-year-old man, presented to get help with tramadol addiction. He had no previous history of illicit drug use, did not smoke cigarettes or drank alcohol.Mr AR was started on tramadol treatment about 2 years earlier for back pain. He did have better pain control with tramadol, but he gradually started taking more and more. Ultimately, his pain resolved but he was unable to stop taking tramadol: he was taking up to 1700 mg/d of tramadol and had made multiple efforts to stop. When he stopped taking tramadol, he had dysphoria, muscle cramps, anxiousness, restlessness, and a sensation of insects crawling all over his body. His withdrawal symptoms were severe enough to interfere with his work and family life.Conclusion:Tramadol dependence is very rare but can happen in a patient without substance abuse history. We, as medical practitioners, should be open to the possibility of tramadol dependence and should resort to optimal and judicious use of such a substance.
2870 – Diabete and Schizophrenia: Retrospective Study
Authors: Ennaoui R. , Jomli R. , Zgueb Y. , Ouertani A. , Nacef F. 
Published: July 2013

Introduction:Type II diabetes is more common in patients with schizophrenia than in the general population. Although disorders of glucose metabolism have been described in patients with schizophrenia before the introduction of atypical antipsychotics, a diabetogenic effect of these has been implicated.Objectives:The aims of our study were to:-assess the prevalence of diabetes in a population of patients with schizophrenia.-determine the relationship between diabetes, atypical antipsychotics and schizophrenia.Patients and methods:This is a retrospective study of 60 patients with schizophrenia. Data collection was done based on patient records.Results:The majority of patients were male with a sex ratio of 2. The average age of our patients was 38 years. 40% of patients (25) had diabetes. 33% of patients were put under an atypical anti psychotic. The diagnosis of diabetes succeeded that of schizophrenia in 40% of cases.Conclusion:Our results indicate that patients with schizophrenia are more likely to develop type II diabetes. We caution clinicians to consider the risk and be vigilant about this development.
2881 – The Interpersonal Theory of Suicide: A French Version of the Interpersonal Needs Questionnaire
Authors: Siefert-Boukaidi M. , Jover F. , Staccini P. , Pringuey D. , Benoit M. 
Published: July 2013

Introduction:The role of social factors in suicidal behaviour is long established. There is growing evidence supporting the Interpersonal Theory of Suicide (ITS), as developed by Joiner et al., which postulates that two psychological dimensions linked to thwarted fundamental interpersonal needs, perceived burdensomeness and thwarted belongingness are linked to the onset of suicidal desire. The Interpersonal Needs Questionnaire (INQ) has been designed to assess those dimensions for use in research on the aetiology of suicidal behaviour and as a component of risk assessment in clinical settings. There is currently no available French version.Aims:Our objective was to provide a French adaptation of the INQ. We translated the INQ, and then examined the construct validity of INQ-F in a clinical setting.Methods:The INQ was translated and administered to 50 patients admitted for suicide attempt or suicidal ideation. Scales with validated French versions were used to assess the following dimensions: suicide risk (Ducher Suicide Risk Assessment Scale (RSD), depression (BDI-SF and MADRS), hopelessness (Beck Hopelessness Scale (BHS) and social vulnerability (EPICES).Results:INQ-F was significantly correlated with suicide risk (rho= .737, p < .001), depression, hopelessness and social isolation. Internal consistency was high (Cronbach's alpha = .9137).Conclusions:Our results support the construct validity of the INQ-F, although complementary studies are needed to further establish it, as well as the relevance of the ITS for suicide risk assessment in clinical settings.
2894 – Effect of Antipsychotic Use Disorder on Metabolic Parameters in Patients with First-Episode Psychosis
Authors: Erdem M. , Zincir S. , Bozkurt Zincir S. , Bilgen A.E. , Koçer M. 
Published: July 2013

Introduction:Because of the different receptor profiles, atypical antipsychotics are known to cause metabolic changes such as increased weight gain, type 2 diabetes and hyperglycemia,.Aim:In this study, we aimed to observe metabolic side effects of drug use of patients receiving antipsychotic medication in first-episode psychotic disorder.Methods:49 male patients who were hospitalized at Gulhane Military Medical Academy Psychiatry Department with a diagnosis of psychotic disorder according to DSM-IV criteria between May 2011–2012 were included in the study. Blood lipid profiles and liver and renal function tests of the patients before treatment and after 8 weeks of treatment were evaluated.Results:Of the patients participating in the study of 16 were using olanzapine, 15 risperidone, 6 quetiapine, 5 aripiprazole and 7 haloperidol. There was no statistically significant difference between patients before and after treatment in terms of blood lipid profile, the liver and kidney functions. There was also no significant difference according to the antipsychotic drug used.Conclusions:In studies with long-term follow-up of 6 months or 1 year or a short-term follow-up as 1 month with atypical antipsychotics these values usually seems to have changed. As a result of 2-month follow-up at our study, patients that were being treated with atypical antipsychotics have not shown any changes in the metabolic values.
2905 – Comparison of Psychological Hardiness with Mental Health Among Male & Female Students
Authors: Ahmadi Gatab T. , Vahedi Ghajari A. 
Published: July 2013

Introduction:Psychological hardiness is one of the powerful personality characteristics individuals posses that can help them improve their ability to cope with illness and external pressures. Some researchers considered psychological hardiness as a general criterion for mental health. That is, hardiness can depict a total outcome of mental health in individuals.Aim:The present study aimed at comparing psychological hardiness with mental health among students in Paym-e-noor University in the city of Babol, Iran.Methodology:A causal-comparative (ex post facto) design was used to carry out this research. All students studying in Babol Payam-e-noor University in academic year 2012–2013 were involved in the statistical population of the research. 200 students were selected through simple random sampling. Tools of this research were both Hardiness and Mental Health Questionnaires used to analyze data with SPSS software.Findings:Results showed a significant difference between psychological hardiness and mental health variables among male and female students. The mean score of illness criteria in male students was significantly higher than that of in female students. Also, the mean score of psychological hardiness variable in female students was higher than that of in male students.Discussion:Psychological hardiness is one of the powerful personality characteristics individuals posses that can help them improve their ability to cope with illness and external pressures. Some researchers considered psychological hardiness as a general criterion for mental health. That is, hardiness can depict a total outcome of mental health in individuals.
2906 – Relationship of Job-Related Stress to the Big Five Personality Factors Among Personnel in Shaid Beheshti Hospitalin Yasuj, Iran
Authors: Jafari L. , Ahmadi Gatab T. , Vahedi Ghajari A. , Babazadeh Bora O. , Mortezazadeh Tori Z. 
Published: July 2013

Introduction and aim:Job-related stress is considered a main factor to cause illness resulting in increaseing nurses’ absence from work. This study investigated the relationship of job-related stress in nursing career to the big five personality factors in personnel in Shahid Beheshti hospital in Yasuj, Iran.Methodology:A correlative study was conducted with statistical population of all nursing personnel in Shahid Beheshti hospital in Yasuj. 83 nurses working in the hospital were randomly selected to form the statistical sample.Findings:Results revealed no significant positive link between Neo personality traits and job-related stress, death-related stress, conflict with doctors, problems with colleagues, problems with supervisors, amount of work, lack of confidence in treatments, patient and their families -related stress and discrimination-related stress whereas a significant positive relationship between the lack of adequately emotional intelligence and neuroticism- two neo personality factors- (P = 018 and R = 259)was observed. Results of regression analysis indicated that neuroticism could only predict one of the job-related stress (i.e. lack of adequately emotional intelligence) (β = 259). This variable explained only 0.05% variance of nurses’ job-related stress. Also, no prediction could be made by considering factors such as introversion-extroversion, openness, dutifulness as associated with job-related stress in nurses while agreeability could affect the prediction of problems with colleagues-related stress(β = 364),which determined 12% of total variance.Conclusion:Results have shown that nurses’ score is at the higher level than mean regarding stress related to lack of confidence in treatments, which can be mitigated through workshops and scheduled and applicable training programs.
2932 – Natural Social Network Project: One for All and All for One
Authors: Papagni S.A. , Grosso A. , Puglisi R. , De Matteis A. , De Giorgi S. 
Published: July 2013

Introduction:Most users of psychiatric services shows jointly clinical severity, disability and marginalization so complex that it can not be answered fully only within the same services.Objectives:Within the Mental Health Department of Lecce, in the Mental Health Center of Casarano it is started the Natural Social Network Project “One for all and all for one” aimed to provide a more adequate response to the needs of these patients.Methods:It will be identified patients with most psychosocial problems according to frequency of hospitalizations, emergency visits and rating scales (Brief Psychiatric Rating Scale, Life Skills Profile and Short Form 36 Health Survey). Then it will be identified with the patient a “facilitator”, or a person outside the CSM and longer fit into the everyday life of the patient (eg, relatives, friends, etc..). After that, the various parties involved (doctor, nurse, facilitator and user) agree an individual program based on which we make a psychoeducational path. The process will be checked quarterly with the presence of all the parties involved and monitored monthly or on the basis of needs.Results:After one trial year it is expected a substantial improvement by the patient in the satisfaction of his needs and more generally in his rehabilitation.
2947 – Suicide Prevention Through Internet Based Mental Health Promotion: The Supreme Project
Authors: Hadlaczky G. , Carli V. , Sarchiapone M. , Värnik A. , Balázs J. , Germanavicius A. , Hamilton R. , Wasserman D. , Masip C. 
Published: July 2013

Suicide is one of the leading causes of death worldwide, and the third leading cause of death among people aged below 25. Mental health promotion is a central aspect of the battle against suicide and mental ill-health. The internet and the media are effective tools for disseminating information and education to adolescents and improving their mental health and well-being. in 2011 there were 2.1 billion Internet users world-wide. in a random sample of over 3000 American adults, it was found that 58% of the Internet users reported searching for health information for themselves (Atkinson et al. 2009).The main objective of the SUPREME project is to develop a website aimed at mental health promotion and to investigate its efficacy. A secondary goal is to compare two different strategies for promoting the use of the website: one where peers are the main promoters and another with mental health professionals. The study is partly funded by the EACH and comprises 7 European countries: Estonia, Hungary, Italy, Spain, United Kingdom, Lithuania and Sweden.Adolescents in this study approached in a random sample of schools, in each participating country, yielding a total of 2100 participants. The schools were randomized into control (minimal intervention), and intervention conditions (minimal intervention + website access). Pre-, post- and follow-up measures are used to test the efficacy of the intervention. Each intervention school is also randomized into peer and pro dissemination groups for comparison of recruitment efficiency. Preliminary results are presented.
2954 – Evidence Based Treatments for Eating Disorders
Authors: Treasure J. 
Published: July 2013

2004 there have been other reviews on specific treatments (forms of psychotherapy Cochrane review)_ and (medication World Biological Psychiatry).In essence however the gist of treatment for eating disorders has not altered over the last 10 years. Involving the family is helpful as an early intervention for anorexia nervosa. It is possible that interventions with several families seen together may be more cost effective.Less is known about which form of treatment is most helpful for those with a more chronic, adult form of illness. Common factors may be relevant as no form of therapy has found robust advantages over another.CBT is effective for about 50% of cases of bulimia and the addition of medication and self directed treatment may increase the remission rate. A similar pattern is apparent for binge eating disorder. More evidence is becoming available on guided self directed care which aside of the advantages of lower cost and transferability appears to have benefits for long term effects even for those with complex presentations. The results of several RCTs are due to be disseminated. Also more brain based interventions are being tried.
2960 – Importance of Physical Health in The Long-Term Management of Bipolar I Disorders
Authors: De Hert M. 
Published: July 2013

Bipolar I disorder is associated with a number of physical health concerns and a higher prevalence of eating, anxiety, and substance abuse disorders compared with the general population. in addition, patients are prone to exhibit risk factors for cardiovascular disease such as obesity, hypertension, hyperglycaemia, dyslipidaemia, and type 2 diabetes.1 Moreover, pharmacotherapy has been linked to metabolic abnormalities that may exacerbate the physical health risk factors and comorbidities prevalent in patients with bipolar disorder.Choosing an initial treatment regimen that takes into account the significant physical health risks associated with bipolar disorder may minimise the subsequent common problem of polypharmacy and may reduce the side-effect burden associated with the disease. Regular monitoring of physical health in the months after initiating pharmacotherapy is essential in preventing and correctly managing comorbidities. Clinicians should gain a comprehensive insight into patient lifestyle choices and should, as part of preventative care, choose treatments according to individual patient risk profiles. If required, clinicians should make recommendations to specialists or facilities offering therapies to minimise key risk factors.2This presentation will review the physical health risks associated with bipolar disorder and with chronic exposure to pharmacotherapy. Because practice guidelines recommend regular physical health monitoring in patients with bipolar disorder, this presentation will discuss approaches to incorporate regular monitoring in routine clinical practice.
2961 – Achieving Symptom Stability for Patients with Bipolar I Disorder
Authors: Vieta E. 
Published: July 2013

The choice of pharmacotherapy for the treatment of bipolar I disorder should balance acute efficacy and long-term effectiveness with minimal side effects. During acute treatment, the primary goal is rapid stabilisation of symptoms, whereas the goal for the long-term management of bipolar I disorder should include relapse prevention, maintenance of a stable mood, and minimise risk of comorbid conditions.1Despite the shift in treatment goals between the acute and the maintenance phase, if a patient responds well to the agent used in the acute phase, this agent frequently will be continued in the maintenance phase. However, achieving continued stability may collide with the goals of minimising the adverse-effect burden associated with treatment, and the subsequent goal of improving patient functioning and quality of life. Sometimes, changing medication regimens may help achieve a balance between efficacy and side-effect burden. However, switching may also be associated with an increased risk of destabilisation. Evidence has shown that patients with bipolar I disorder often have a predominant episode polarity, which is a predictor of treatment response.2 Therefore, when assessing long-term treatment options, consideration should be given from the outset to the available clinical evidence for preventing the recurrence of mood episodes, as well as the predominant polarity of the patient.3Because patient polarity plays an important role in the success of pharmacotherapy, this presentation will review the concept of predominant polarity in clinical practice and discuss the potential value of considering a drug's polarity index in the development of individualised long-term treatment regimens.