bluuebunny/crossref_metadata_2025_split huggingface dataset:
Time‐dependent recovery of microcrack damage and seismic wave speeds in deformed limestone
Authors: Brantut Nicolas 
Published: November 2015

AbstractLimestone samples were deformed up to 5% inelastic axial strain at an effective confining pressure Peff=50 MPa in the cataclastic flow regime and subsequently maintained under constant static stress conditions (either isostatic of triaxial) for extended periods of time while elastic wave speeds and permeability were continuously monitored. During deformation, both seismic wave speeds and permeability decrease with increasing strain, due to the growth of subvertical microcracks and inelastic porosity reduction. During the static hold period under water‐saturated conditions, the seismic wave speeds recovered gradually, typically by around 5% (relative to their initial value) after 2 days, while permeability remained constant. The recovery in wave speed increases with increasing confining pressure but decreases with increasing applied differential stress. The recovery is markedly lower when the samples are saturated with an inert fluid as opposed to water. The evolution in wave speed is interpreted quantitatively in terms of microcrack density, which shows that the post‐deformation recovery is associated with a decrease in effective microcrack length, typically of the order to 10% after 2 days. The proposed mechanism for the observed damage recovery is microcrack closure due to a combination of backsliding on wing cracks driven by time‐dependent friction and closure due to pressure solution at contacts between propping particles or asperities and microcrack walls. The recovery rates observed in the experiments, and the proposed underlying mechanisms, are compatible with seismological observations of seismic wave speed recovery along faults following earthquakes.
Geomechanical simulation of the stress tensor rotation caused by injection of cold water in a deep geothermal reservoir
Authors: Jeanne Pierre , Rutqvist Jonny , Dobson Patrick F. , Garcia Julio , Walters Mark , Hartline Craig , Borgia Andrea 
Published: November 2015

AbstractWe present a three‐dimensional thermohydromechanical numerical study of the evolution and distribution of the stress tensor within the northwest part of The Geysers geothermal reservoir (in California), including a detailed study of the region around one injection well from 2003 to 2012. Initially, after imposing a normal faulting stress regime, we calculated local changes in the stress regime around injection wells. Our results were compared with previously published studies in which the stress state was inferred from inverting the focal plane mechanism of seismic events. Our main finding is that changes in stress tensor orientation are caused by injection‐induced progressive cooling of the reservoir, as well as by the seasonal variations in injection rate. Because of the gravity flow and cooling around a liquid zone formed by the injection, the vertical stress reduction is larger and propagates far below the injection well. At the same time, the horizontal stress increases, mostly because of stress redistribution below and above the cooling area. These two phenomena cause the rotation of the stress tensor and the appearance of a strike‐slip regime above, inside, and below the cooling area. The cooling and the associated rotation of the stress regime can play a significant role in the observed long‐term deepening of the microseismicity below active injection wells.
Modeled ocean circulation in Nares Strait and its dependence on landfast‐ice cover
Authors: Shroyer Emily L. , Samelson Roger M. , Padman Laurie , Münchow Andreas 
Published: November 2015

AbstractTwo simplified ocean simulations are used to study circulation and transport within Nares Strait. The simulations are similar, except that one included a coupled sea ice model that effectively established a landfast ice cover throughout the simulation year. Comparison between the ocean‐only and ocean‐ice simulations reveals a systematic change in the current structure, reminiscent of the seasonal shift under mobile and landfast ice previously observed in Nares Strait. A surface‐intensified jet, which carries low‐salinity water along the strait's centerline, develops within the ocean‐only simulation. The current structure under landfast ice is characterized by a subsurface jet located along the western side with low‐salinity surface water distributed along the eastern side of the strait. Intermediate salinity water is offset to the west in the ice‐ocean simulation relative to the ocean‐only simulation, while high‐salinity water (>34.8) is constrained to recirculations that are located north and south of a sill in Kane Basin. The simulations, combined with an idealized, semianalytical model, suggest that the structural shift is caused by the surface Ekman layer beneath the landfast ice and the associated eastward advection of near‐surface low‐salinity water and westward movement of the jet. Temporal variability in the ocean‐ice simulation is dominated by the remote response to the time‐dependent northern boundary conditions. In contrast, the ocean‐only simulation favors an instability and additionally responds to local surface wind forcing, which enhances the variability within the strait above that imposed at the boundaries.
Young‐onset frontotemporal dementia in a homozygous tau R406W mutation carrier
Authors: Ng Adeline S. L. , Sias Ana C. , Pressman Peter S. , Fong Jamie C. , Karydas Anna M. , Zanto Theodore P. , De May Mary , Coppola Giovanni , Geschwind Daniel H. , Miller Bruce L. , Lee Suzee E. 
Published: November 2015

AbstractMicrotubule‐associated protein tau mutations result in 10–20% of cases of genetic frontotemporal lobar degeneration. Tau mutation carriers typically develop behavioral variant frontotemporal dementia with or without parkinsonism. Unlike most frontotemporal dementia gene mutations, heterozygous R406W tau mutation carriers most often develop clinical Alzheimer's disease. We report a homozygous tau R406W mutation carrier with behavioral variant frontotemporal dementia who developed symptoms 20 years before mean family symptom onset. Voxel‐based morphometry showed frontoinsular, frontal, and mesial temporal cortical atrophy. Homozygous tau R406W mutations appear to accelerate symptom onset and drive a behavioral variant frontotemporal dementia syndrome.
TAS2R38 genotype predicts surgical outcome in nonpolypoid chronic rhinosinusitis
Authors: Adappa Nithin D. , Farquhar Douglas , Palmer James N. , Kennedy David W. , Doghramji Laurel , Morris Shane A. , Owens David , Mansfield Corrine , Lysenko Anna , Lee Robert J. , Cowart Beverly J. , Reed Danielle R. , Cohen Noam A. 
Published: November 2015

BackgroundOver 550,000 sinus surgeries are performed annually in the United States on patients with chronic rhinosinusitis (CRS). Although the results of sinus surgery vary widely, no known genetic factor has been identified to predict surgical outcomes. The bitter taste receptor T2R38 has recently been demonstrated to regulate upper airway innate defense and may affect patient responses to therapy. Our goal was to determine whether TAS2R38 genetics predicts outcomes in CRS patients following sinus surgery.MethodsA prospective study of patients undergoing sinus surgery evaluating postoperative outcomes through the 22‐item Sino‐Nasal Outcome Test (SNOT‐22). Patients were genotyped for TAS2R38.ResultsA total of 123 patients with CRS were initially analyzed; 82 patients showed nasal polyps (CRSwNP) and 41 patients were without nasal polyps (CRSsNP). Six months after surgery, the overall SNOT‐22 improvement was 25 ± 23 points. The TAS2R38 genotype was found to significantly correlate with surgical outcomes in patients without polyps; homozygotes for the functional receptor had a mean improvement of 38 ± 21, whereas heterozygotes or homozygotes for the nonfunctional receptor had a mean improvement of 12 ± 22 (p = 0.006). This result was confirmed with a multivariate regression that incorporated further patients with 1‐month and 3‐month scores (n = 207).ConclusionIn patients undergoing sinus surgery for CRS, we have identified a genetic polymorphism that predicts variability in quality of life improvement following surgery at 6 months in nonpolypoid CRS. This is the first genetic polymorphism identified that has demonstrated to predict surgical outcome for a select group of CRS patients.
Profuse bleeding from a pseudoaneurysm of the right superior thyroid artery after tracheostomy
Authors: Tanaka Koichi , Tachibana Naoto , Sato Hirokazu , Uematsu Keigo , Shiba Yosuke , Hamami Gen 
Published: November 2015

CaseA 70‐year‐old man was brought to our hospital emergency department with accidental thermal burns. Surgical tracheostomy was carried out on day 8 after admission, followed by several profuse bleeding episodes from the orifice. Contrast‐enhanced computed tomography of the neck revealed a small nodule with arterial phase enhancement that was suspected to be a pseudoaneurysm. During emergency angiography, the nodule was revealed to be a pseudoaneurysm arising from the right superior thyroid artery with contrast medium extravasation.OutcomeThe patient underwent transcatheter arterial embolization, which resolved bleeding from the tracheostomy orifice.ConclusionPseudoaneurysm of the superior thyroid artery is an extremely rare and life‐threatening tracheostomy complication. All clinicians certified to perform tracheostomy should be acquainted with the various complications and methods for managing life‐threatening post‐tracheostomy complications.
A laboratory exercise to illustrate protein–membrane interactions
Authors: Weers Paul M.M. , Prenner Elmar J. , Curic Spomenka , Lohmeier‐Vogel Elke M. 
Published: November 2015

AbstractThe laboratory protocol presented here takes about 3 hours to perform and investigates protein and lipid interactions. Students first purify His6‐tagged human apolipoprotein A‐I (apoA‐I) with Ni‐NTA affinity resin in a simple batch protocol and prepare multilamellar vesicles (MLV) from pre‐dried phospholipid films. When apoA‐I is added to the MLV, much smaller protein/lipid nanodisc complexes are formed in some instances. Nanodisc formation can be monitored by a decrease in light‐scattering intensity at 340 nm using a simple spectrophotometer. Students will observe nanodisc formation with MLV formed from the anionic phospholipid dimyristoylphosphatidyl glycerol, which pack poorly into lipid bilayers, but not with MLV formed from the zwitterionic phospholipid dimyristoyl phosphatidylcholine, which form stable bilayers. This laboratory exercise is accompanied by questions and exercises that enable students a deeper of the dimensions of apoA‐I and nanodiscs as well as the biological relevance of nanodisc formation in the process of reverse cholesterol transport. © 2015 by The International Union of Biochemistry and Molecular Biology, 44:86–94, 2016.
The values and motivations behind sustainable fashion consumption
Authors: Lundblad Louise , Davies Iain A. 
Published: November 2015

AbstractThe growth in ethical consumption behaviour and greater interest in sustainable fashion from a production side provides grounding for the emergence of a new consumer market for sustainable fashion. To date, however, most studies in this field focus on the production end of the emerging market, with little exploration of the consumers. Of the work, there is on sustainable fashion consumption; the majority discuss perceptions of sustainable fashion by the general population, with little work sampling actual consumers of sustainable fashion. Therefore, the purpose of this study is to explore the values and motivations underpinning actual sustainable fashion consumption. Thirty‐nine in‐depth interviews were conducted with a sample of frequent sustainable clothing consumers. The study follows a means‐end theory approach linking purchased products back to purchasing criteria and personal values. This study therefore contributes to the overall understanding of sustainable fashion consumption and gives insights into purchasing criteria and behavioural choices of sustainable fashion consumers. Copyright © 2015 John Wiley & Sons, Ltd.
A Helix‐Stabilized Cell‐Penetrating Peptide as an Intracellular Delivery Tool
Authors: Yamashita Hiroko , Oba Makoto , Misawa Takashi , Tanaka Masakazu , Hattori Takayuki , Naito Mikihiko , Kurihara Masaaki , Demizu Yosuke 
Published: November 2015

AbstractTwo types of cationic cyclic α,α‐disubstituted α‐amino acids: Api
(which possesses a lysine mimic side chain) and ApiC2Gu (which possesses an arginine mimic side chain), were developed. These amino acids were incorporated into an arginine‐based peptide sequence [(l‐Arg‐l‐Arg‐dAA)3: dAA=Api
or ApiC2Gu], and the relationship between the secondary structures of the resulting peptides and their ability to pass through cell membranes was investigated. The peptide containing ApiC2Gu formed a stable α‐helical structure and was more effective at penetrating cells than the nonhelical Arg nonapeptide (R9). Furthermore, the peptide was able to deliver plasmid DNA into various types of cells in a highly efficient manner.
Organic Solvent Nanofiltration‐Supported Purification of Organocatalysts
Authors: Großeheilmann Julia , Fahrenwaldt Thomas , Kragl Udo 
Published: November 2015

AbstractIn this study, the successful use of organic solvent nanofiltration for the purification of three highly enantioselective quinine‐based organocatalysts was demonstrated. Commercially available solvent‐resistant membranes (DuraMem series) were utilized to remove specific impurities that originated from their respective synthesis pathways. DuraMem 200 exhibited the highest catalyst retention of 99 %, which facilitated catalyst purification at the gram scale with a purity >99 %.
Combining Acoustic Emission and Vibration Technologies Harbors Huge Potential for Material Characterization
Authors: Nienhaus Karl , Wotruba Hermann , Boos Domenic , Klösges Simon , Vraetz Tobias , Neubert Kilian 
Published: November 2015

AbstractThe demand for raw materials is growing worldwide, in step with increasing world population and rising living standards of emerging countries. It is becoming more difficult to exploit primary raw materials because of declining ore grades and increasingly complicated mineralogies. Thus, the efficient and environmentally sustainable exploitation of primary resources using innovative technologies has emerged as an important research field to address these issues. An innovative approach is introduced to optimize process and quality control by combining acoustic emission (AE) and vibration technology. The general feasibility of these two technologies for material recognition and characterization is examined. The new approach was tested to determine whether coal could be distinguished from waste rock.
ChemInform Abstract: Crystal Structure and Magnetic Properties of SrNi2‐xSb2.
Authors: Gvozdetskyi Volodymyr , Hlukhyy Viktor , Gladyshevskii Roman , Faessler Thomas F. 
Published: November 2015

AbstractThe intermetallic title phase is prepared by arc‐melting of the elements followed by annealing (1370 K for 2 h and 1070 K for 96 h).
ChemInform Abstract: A High‐Voltage and Ultralong‐Life Sodium Full Cell for Stationary Energy Storage.
Authors: Guo Shaohua , Liu Pan , Sun Yang , Zhu Kai , Yi Jin , Chen Mingwei , Ishida Masayoshi , Zhou Haoshen 
Published: November 2015

AbstractA P2‐layered Na0.66Ni0.17Co0.17Ti0.66 O2 electrode material is prepared by solid state reaction of a stoichiometric mixture of Na2CO3, NiO, CoO, and TiO2 with a 5 wt% excess of Na2CO3 under Ar (900 °C, 15 h).
ChemInform Abstract: Synthesis, Crystal Structures, and Optical Properties of AM2(OH)(SeO3)2 (A: Na, Rb; M: Mg, Zn).
Authors: Liu Yunsheng , Mei Dajiang , Xu Jingli , Wu Yuandong 
Published: November 2015

AbstractThe crystal structures of compounds (IV) and (VII) are determined by single crystal XRD.
ChemInform Abstract: Crystal Chemistry of the M11+,2+—M22+,3+—(H)‐Arsenites: The First Cadmium(II) Arsenite, Na4Cd7(AsO3)6.
Authors: Dordevic Tamara 
Published: November 2015

AbstractSingle crystals of Na4Cd7(AsO3)6 are hydrothermally synthesized from aqueous mixtures of NaOH, CdO, and As2O3 in the molar ratio of 1:2:2 (autoclave, 220 °C, 52 h, 95% yield).
ChemInform Abstract: CH3NH3SnxPb1‐xBr3 Hybrid Perovskite Solid Solution: Synthesis, Structure, and Optical Properties.
Authors: Mancini Alessandro , Quadrelli Paolo , Milanese Chiara , Patrini Maddalena , Guizzetti Giorgio , Malavasi Lorenzo 
Published: November 2015

AbstractSingle‐phase (MeNH3)SnxPb1‐xBr3 (x = 0‐1) solid solutions are precipitated from aqueous solutions of Pb(O‐Ac)2 and SnBr2, MeNH2, excess HBr, and H4P2O6 (100→46 °C).
ChemInform Abstract: Four New Actinide Chalcogenides Ba2Cu4USe6, Ba2Cu2ThSe5, Ba2Cu2USe5, and Sr2Cu2US5: Crystal Structures and Physical Properties.
Authors: Mesbah Adel , Prakash Jai , Beard Jessica C. , Lebegue Sebastien , Malliakas Christos D. , Ibers James A. 
Published: November 2015

AbstractBa2Cu4USe6 (I), Ba2Cu2ThSe5 (II), Ba2Cu2USe5 (III), and Sr2Cu2US5 (IV) are prepared by melting stoichiometric mixtures of the elements in a CsCl flux (carbon‐coated evacuated silica tube, 1173 K, 96 h; <80% yield of (I) and (IV)).
ChemInform Abstract: Heterometallic 3d—4f Cluster‐Containing Polyoxotungstate Obtained by Partial Disassembly of Preformed Large Clusters.
Authors: Yao Shuang , Yan Jing‐Hui , Duan Hui , Jia Qian‐Qian , Zhang Zhi‐Ming , Wang En‐Bo 
Published: November 2015

AbstractCrystals of the new compound KNa5{K2Dy2Cu2 (H2O)8 (SbW9O33)2}·17H2O are prepared by reacting a conc.
ChemInform Abstract: Bifunctional Organocatalysts for the Enantioselective Synthesis of Axially Chiral Isoquinoline N‐Oxides.
Authors: Miyaji Ryota , Asano Keisuke , Matsubara Seijiro 
Published: November 2015

AbstractThe aromatic electrophilic bromination of isoquinoline N‐oxides (I) and (III) with N‐bromoacetamide in the presence of a cinchona‐derived catalyst gives rise to axially chiral products (II) and (IV).
ChemInform Abstract: Synthesis and Structures of Ruthenium—NHC Complexes and Their Catalysis in Hydrogen Transfer Reaction.
Authors: Chen Chao , Lu Chunxin , Zheng Qing , Ni Shengliang , Zhang Min , Chen Wanzhi 
Published: November 2015

AbstractRuthenium—NHC complexes bearing pyrimidine‐ and pyridine‐functionalized NHC ligands are prepared and utilized as highly efficient catalysts in transfer hydrogenation of ketones.
ChemInform Abstract: Reductive Alkylation of Arenes by a Thiol‐Based Multicomponent Reaction.
Authors: Parnes Regev , Pappo Doron 
Published: November 2015

AbstractVarious arenes endowed with electron‐donating substituents are transformed in an alkylthiol‐promoted chemo‐ and regioselective aromatic substitution with a diverse range of aryl and alkyl aldehydes.
ChemInform Abstract: Alkenyl Carbonyl Derivatives in Enantioselective Redox Relay Heck Reactions: Accessing α,β‐Unsaturated Systems.
Authors: Zhang Chun , Santiago Celine B. , Kou Lei , Sigman Matthew S. 
Published: November 2015

AbstractArylation of various alkene substrates linked to carbonyl functions is investigated under the optimized conditions A) to produce a broad spectrum of functionalized α,β‐unsaturated structures with high enantioselectivities.
ChemInform Abstract: Conversion of 2‐Iodobiaryls into 2,2′‐Diiodobiaryls via Oxidation‐Iodination Sequences: A Versatile Route to Ladder‐Type Heterofluorenes.
Authors: Wu Bin , Yoshikai Naohiko 
Published: November 2015

AbstractThe two‐step method yields 2,2‐diiodobiaryls from 2‐iodobiaryls through an oxidative cyclization/copper‐catalyzed iodinative ring‐opening sequence.
ChemInform Abstract: A Systematic Approach to Diverse, Lead‐Like Scaffolds from α,α‐Disubstituted Amino Acids.
Authors: Foley Daniel J. , Doveston Richard G. , Churcher Ian , Nelson Adam , Marsden Stephen P. 
Published: November 2015

AbstractFour amino acid‐derived building blocks are converted into 22 scaffolds, e.g. azides (III) and (XIV), hydantoins (IV), lactams (VI), tetrahydropyridines (IX), and azepanes (XII).
ChemInform Abstract: Copper‐Catalyzed Trifluoromethylazidation of Alkynes: Efficient Access to CF3‐Substituted Azirines and Aziridines.
Authors: Wang Fei , Zhu Na , Chen Pinhong , Ye Jinxing , Liu Guosheng 
Published: November 2015

AbstractThis novel method gives access to CF3‐containing azirines via a copper‐catalyzed trifluoromethylazidation followed by a photocatalyzed rearrangement.
ChemInform Abstract: Lewis Acid Catalyzed Annulation of Donor—Acceptor Cyclopropane and N‐Tosylaziridinedicarboxylate: One‐Step Synthesis of Functionalized 2H‐Furo[2,3‐c]pyrroles.
Authors: Ghosh Asit , Pandey Ashok Kumar , Banerjee Prabal 
Published: November 2015

AbstractDiastereoselective cyclization of 1,1‐cyclopropanedicarboxylates with 2,2‐aziridinedicarboxylates using MgI2 yields saturated 2H‐furo[2,3‐c]pyrroles.
ChemInform Abstract: Construction of an All‐Carbon Quaternary Stereocenter by Organocatalytic Enantioselective α‐Functionalization of α‐Substituted β‐Ketocarbonyls with Electron Deficient Vinylarenes.
Authors: Liu Shizhou , Tong Mengchao , Yu Yang , Xie Hexin , Li Hao , Wang Wei 
Published: November 2015

AbstractThe enantioselective reaction of ketones (II) and (VI) with vinylarenes (I) gives rise to desired dicarbonyl compounds (III) and (VII), which are readily converted into chiral pyrazolones (V) and (VIII), respectively.
ChemInform Abstract: Asymmetric Isothiourea‐Catalyzed Formal [3 + 2] Cycloadditions of Ammonium Enolates with Oxaziridines.
Authors: Smith Siobhan R. , Fallan Charlene , Taylor James E. , McLennan Ross , Daniels David S. B. , Morrill Louis C. , Slawin Alexandra M. Z. , Smith Andrew D. 
Published: November 2015

AbstractThe title process is investigated with racemic oxaziridine (II) under conditions A).
ChemInform Abstract: Copper Nitrate Mediated Regioselective [2 + 2 + 1] Cyclization of Alkynes with Alkenes: A Cascade Approach to Δ2‐Isoxazolines.
Authors: Gao Mingchun , Li Yingying , Gan Yuansheng , Xu Bin 
Published: November 2015

AbstractThe regioselective synthesis of pharmacologically relevant polysubstituted Δ2—isoxazolines is based on the copper‐mediated direct transformation of terminal alkynes and alkenes.
ChemInform Abstract: The Vilsmeier—Haack Formylation of 2,3‐Dihydro‐4H‐1,3‐benzoxazin‐4‐ones and Isomeric 1,2‐Dihydro‐4H‐3,1‐benzoxazin‐4‐ones: An Effective Approach to Functionalized 2H‐/4H‐Chromenes and Tetrahydroacridines.
Authors: Farat Oleg K. , Markov Victor I. , Varenichenko Svetlana A. , Dotsenko Victor V. , Mazepa Alexander V. 
Published: November 2015

AbstractIt is demonstrated, that 1,3‐benzoxazin‐4‐ones react with Vilsmeier reagent to give chromene derivatives in generally good yields.
ChemInform Abstract: Cobalt‐Catalyzed Dual Annulation of o‐Halobenzaldimine with Alkyne: A Powerful Route Toward Bioactive Indenoisoquinolinones.
Authors: Liu Chuan‐Che , Hsieh Jen‐Chieh , Korivi Rajendra Prasad , Cheng Chien‐Hong 
Published: November 2015

AbstractThe dual annulation of alkyne (VIII) with isolated aldimine (IX) leads to known bioactive tetracyclic derivative (X).
ChemInform Abstract: Synthesis of Benzoxepinopyrrolidines/Spiropyrrolidines via oxa‐Pictet—Spengler and [3 + 2] Cycloaddition Reactions.
Authors: Bakthadoss Manickam , Sivakumar Nagappan , Devaraj Anthonisamy 
Published: November 2015

AbstractOxa‐Pictet—Spengler cyclization of Baylis—Hillman adducts with paraformaldehyde gives benzoxepines (III), which undergo [3 + 2] cycloaddition reactions with in situ generated azomethine ylides to form fused pyrrolidine derivatives.
ChemInform Abstract: Mn(III)‐Mediated Phosphonation—Azidation of Alkenes: A Facile Synthesis of β‐Azidophosphonates.
Authors: Xu Jian , Li Xueqin , Gao Yuzhen , Zhang Liangliang , Chen Weizhu , Fang Hua , Tang Guo , Zhao Yufen 
Published: November 2015

AbstractA new and general method for the synthesis of a broad variety of β‐azidophosphonates (26 examples) is developed.