bluuebunny/crossref_metadata_2025_split huggingface dataset:
Supramolecular Polymers
Authors: Nieuwenhuizen Marko M. L. , Appel Wilco P. J. , Meijer E. W. 
Published: February 2013

Abstract
The sections in this article are

Introduction

Supramolecular Chemistry

Supramolecular Polymerization Mechanisms

Examples of Supramolecular Polymers

Supramolecular Polymers Based on the Hydrogen‐Bonding Bis‐Urea Motif

Supramolecular Polymers in Water

Supramolecular Polymeric Materials

Supramolecular Block Copolymers

Self‐Healing Materials

Future Perspectives
Self‐Healing and Antifouling Multifunctional Coatings Based on pH and Sulfide Ion Sensitive Nanocontainers
Authors: Zheng Zhaoliang , Huang Xing , Schenderlein Matthias , Borisova Dimitriya , Cao Rong , Möhwald Helmuth , Shchukin Dmitry 
Published: February 2013

AbstractApplication of mesoporous silica nanoparticles (MSNs) as delivery tools for self‐healing coatings is limited by spontaneous leakage and specifically responsive release of small molecular inhibitors. In this work, a pH/sulfide ion responsive release system based on MSNs using a Cu‐BTA complex forms at the openings of the mesopores into which BTA (corrosion inhibitor) and benzalkonium chloride (biocide) are loaded. The spontaneous leakage of active species is completely avoided and premature release of the loaded composition was lowered to 0.02. The responsive release begins when the pH is lower than 5 or [S2−] is higher than 0.02 mM (about 0.6 ppm). The hybrid coating containing the responsive release system exhibits feedback self‐healing property sensitive to lowering of pH and sulfide ion concentration and, at the same time, provides a high barrier level for a long time. Due to incorporation of biocide in the release system, the coating is also provided with antifouling properties.
Maternal obesity, folate intake, and neural tube defects in offspring
Authors: McMahon Daria M. , Liu Jihong , Zhang Hongmei , Torres Myriam E. , Best Robert G. 
Published: February 2013

AbstractBACKGROUNDWe investigated the association between maternal obesity (body mass index [BMI] ≥ 30) and the risk of a neural tube defect affected pregnancy (NTD). We also studied relationships between perinatal folate intake from food and the NTD risk by maternal BMI.METHODSData came from a state‐wide case‐control study conducted between 1992 and 1997 in South Carolina including 179 women with NTD‐affected pregnancies and 288 women without NTD‐affected births. A majority of case mothers (77%) and controls (86%) were interviewed within 6 months after delivery or pregnancy termination. Logistic regression models were used to examine the association between maternal obesity and the NTD risk after adjusting for maternal race, age, education, smoking, alcohol/drug use, chronic conditions, and multivitamin use within six periconceptional months. Stratified analysis by maternal BMI (≥25 vs. <25) was conducted for the association between food folate and the NTD risk.RESULTSAfter adjustment for confounders, obese women (BMI ≥ 30) had twice higher odds of having an NTD‐affected pregnancy (odds ratios [OR] = 2.06, 95% confidence interval [CI] = 1.12, 3.81) than normal weight women (BMI: 18.0–24.9). Compared to the lowest quartile of average daily folate intake from food, the upper three quartiles had lower odds of NTDs in offspring. The NTD‐protective association was stronger in overweight/obese women (BMI ≥ 25) than in normal/underweight women (BMI < 25).CONCLUSIONSThese results support previous studies suggesting maternal obesity as a risk factor for NTDs. Higher intakes of dietary folate were associated with decreased NTD risk that was stronger in overweight and obese women. Birth Defects Research (Part A) 2013. © 2013 Wiley Periodicals, Inc.
ChemInform Abstract: Crystal Structure and Chemistry of a Complex Indium Phosphate Framework Material, (Ethylenediammonium)In3P3O12 (OH)2.
Authors: Broach Robert W. , Bedard Robert L. , King Lisa M. , Pluth Joseph J. , Smith Joseph V. , Kirchner Richard M. 
Published: February 2013

AbstractThe title compound is obtained from a gel of InCl3, H3PO4, SiO2, en, and H2O (200—225 °C, 4—10 d).
ChemInform Abstract: Mesoporous Vanadium Nitride as a High Performance Catalyst Support for Formic Acid Electrooxidation.
Authors: Yang Minghui , Cui Zhiming , DiSalvo Francis J. 
Published: February 2013

AbstractMesoporous VN with high surface area and good electrical conductivity is prepared from Zn3V2O8 in a flow of ammonia gas (600 °C, 12 h).
ChemInform Abstract: ortho‐Amidoalkylation of Phenols via Tandem One‐Pot Approach Involving Oxazine Intermediate.
Authors: Mudududdla Ramesh , Jain Shreyans K. , Bharate Jaideep B. , Gupta Ajai P. , Singh Baldev , Vishwakarma Ram A. , Bharate Sandip B. 
Published: February 2013

AbstractTreatment of phenols with HCHO and lactams in the presence of HClO4‐SiO2 allows a new and efficient method to prepare ortho‐amidoalkylated phenols.
ChemInform Abstract: Catalytic Asymmetric Nitroaldol (Henry) Reactions with Copper(II)/Cyclopropane‐Based Bisoxazoline Complexes.
Authors: Mao Jianyou , Nie Xin , Wang Min , Wang Qian , Zheng Bing , Bian Qinghua , Zhong Jiangchun 
Published: February 2013

AbstractThe used ligand is prepared in a two‐step synthesis.
ChemInform Abstract: Synthesis of Enantiomerically Enriched 3‐Amino‐2‐oxindoles Through a Palladium‐Mediated Asymmetric Intramolecular Arylation of α‐Ketimino Amides.
Authors: Tolstoy Paeivi , Lee Samantha X. Y. , Sparr Christof , Ley Steven V. 
Published: February 2013

AbstractThe use of an iodide instead of the triflate leaving group provides only a trace of a racemic product.
ChemInform Abstract: A Tandem Heck—aza‐Michael Addition Protocol for the One‐Pot Synthesis of Isoindolines from Unprotected Amines.
Authors: Chen Ke , Pullarkat Sumod A. 
Published: February 2013

AbstractBesides t‐butyl, n‐butyl, methyl and ethyl, acrylates can be used as starting material as well as acrylamide.
ChemInform Abstract: Catalyst‐Free Intramolecular Oxidative Cyclization of N‐Allylbenzamides: A New Route to 2,5‐Substituted Oxazoles.
Authors: Zhou Wei , Xie Chen , Han Jianlin , Pan Yi 
Published: February 2013

AbstractThe C—Br bond of the oxazoles provides an easy access to useful building blocks.
ChemInform Abstract: Iron Catalyzed Asymmetric Oxyamination of Olefins.
Authors: Williamson Kevin S. , Yoon Tehshik P. 
Published: February 2013

AbstractN‐Sulfonyl oxaziridines react with terminal alkenes in the presence of a novel iron(II)/chiral bis(oxazoline) catalyst to give oxazolidines with excellent regio‐ and diastereoselectivity (cis:trans <10:1), and with up to 95% enantioselectivity.
ChemInform Abstract: N‐Heterocyclic Carbene Catalyzed Annulation of α‐Cyano‐1,4‐diketones with Ynals.
Authors: Romanov‐Michailidis Fedor , Besnard Celine , Alexakis Alexandre 
Published: February 2013

AbstractThe method allows the preparation of various furo‐pyran systems with 3 stereogenic centers.
ChemInform Abstract: New N‐Substituted (E)‐4‐Arylidene Isoquinoline‐1,3‐dione Derivatives: NMR Spectroscopic Investigation and Antibacterial Activity.
Authors: Jegham Nafaa , Tka Najeh , Kacem Vakdhane , Hassine Bechir Ben 
Published: February 2013

AbstractCondensation products (III) are obtained exclusively as (E)‐isomers.
ChemInform Abstract: CuCl‐Catalyzed Green and Efficient One‐Pot Synthesis of Aminoindolizine Frameworks via Three‐Component Reactions of Aldehydes, Secondary Amines, and Terminal Alkynes in PEG.
Authors: Mishra Sarita , Naskar Bikramaditya , Ghosh Rina 
Published: February 2013

AbstractA series of biologically potent frameworks (15 examples) is readily available by the process.
ChemInform Abstract: AlCl3/PCC‐SiO2‐Promoted Oxidation of Azaindoles and Indoles.
Authors: Sriram Rekulapally , Kumar Chebolu Naga Sesha Sai Pavan , Raghunandan Nerella , Ramesh Vadla , Sarangapani Manda , Rao Vaidya Jayathirtha 
Published: February 2013

AbstractA very simple and efficient protocol for the title reaction is described.
ChemInform Abstract: Palladium‐Catalyzed Synthesis of Substituted Pyrido[2,3‐d]pyridazines at Positions 5 and 8.
Authors: Bihel Frederic , et al. et al. 
Published: February 2013

AbstractA series of Pd‐catalyzed reactions starting from chloro‐substituted substrates (I) or (IV) are applied to synthesize the corresponding 5‐ and 8‐substituted derivatives.
ChemInform Abstract: Fe3O4/SiO2 Nanoparticles: An Efficient and Magnetically Recoverable Nanocatalyst for the One‐Pot Multicomponent Synthesis of Diazepines.
Authors: Maleki Ali 
Published: February 2013

AbstractThe present new one‐pot multicomponent reaction of a diamine, a linear or cyclic ketone, and an isocyanide proceeds in the presence of a silica‐supported iron oxide catalyst affording diazepine derivatives in high yields.
ChemInform Abstract: Facile Synthesis of Electrophilic Vinyl Boranes: Reactions of Alkynyl‐Borates and Diazonium Salts.
Authors: Zhao Xiaoxi , Liang Liyuan , Stephan Douglas W. 
Published: February 2013

AbstractThe title reaction is thought to proceed via the interaction of the electron‐deficient cation derived from the diazonium salt (II) and the alkyne fragment of the alkynylborate (I) generating a transient carbocation adjacent the borate center.
ChemInform Abstract: A Novel Regioselective Reaction of Styrene with Magnesium Organoselenolates to Afford Unsymmetrical Selenides Catalyzed by CuI and L‐Proline.
Authors: Gao Fei , Tang Yu , Li Zhi‐hao , Pan Feng , Yang Jun , Zhang Yuan‐ming 
Published: February 2013

AbstractAryl‐ and alkyl bromides can be used as substrates to yield the unsymmetrical selenides in a regioselective manner.
A phase 1 study of everolimus plus docetaxel plus cisplatin as induction chemotherapy for patients with locally and/or regionally advanced head and neck cancer
Authors: Fury Matthew G. , Sherman Eric , Ho Alan L. , Xiao Han , Tsai Frank , Nwankwo Oby , Sima Camelia , Heguy Adrian , Katabi Nora , Haque Sofia , Pfister David G. 
Published: February 2013

AbstractBACKGROUND:Activation of the phosphatidylinositol‐3‐kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) pathway is common in head and neck cancers, and it has been demonstrated that inhibition of mTOR complex 1 sensitizes cell lines to platinum and taxane chemotherapy. The authors conducted a phase 1 study to evaluate the addition of oral everolimus to cisplatin and docetaxel as induction chemotherapy for head and neck cancer.METHODS:In this single‐institution phase 1 study, 3 doses of daily everolimus were explored: 5 mg daily, 7.5 mg daily (administered as 5 mg daily alternating with 10 mg daily), and 10 mg daily of each 21‐day cycle. Cisplatin and docetaxel doses were fixed (both were 75 mg/m2 on day 1 of 21‐day cycle) at each dose level with pegfilgrastim support. A standard 3 + 3 dose‐escalation plan was used. After induction, patients were removed from protocol.RESULTS:Eighteen patients were enrolled (15 men, 3 women), and their median Karnofsky performance status was 90. The most common toxicities were hyperglycemia, low hemoglobin, fatigue, and thrombocytopenia. Dose‐limiting toxicities (DLTs) were neutropenic fever (1 event at dose level 2, 2 events at dose level 3), and all patients recovered fully from these DLTs. The maximum tolerated dose was exceeded at dose level 3. The progression‐free survival rate at 1 year was 87.5% (95% confidence interval, 56.8%‐96.7%); and, at 2 years, it was 76.6% (95% confidence interval, 41.2%‐92.3%). Activating PI3K catalytic subunit α (PIK3CA) gene mutations were identified in 2 human papillomavirus‐associated oropharyngeal cancers.CONCLUSIONS:The phase 2 recommended dose was 7.5 mg daily for everolimus plus cisplatin and docetaxel (both at 75 mg/m2 on day 1 of a 21‐day cycle) given with pegfilgrastim support. Cancer 2013. © 2013 American Cancer Society.
Processes in phase boundary region during liquid phase growth
Authors: Peev N. S. 
Published: February 2013

AbstractThe behavior of components within the phase boundary region during liquid phase growth is the subject of the present article. Based on the supposition that the phase boundary is a structured region, repeating the periodicity of the substrate, the distribution of different components within the phase boundary is considered. Assuming that the value of the supersaturation at the upper end of the phase boundary defines the growth rate of the compound, a relation has been derived, concerning the extension of the phase boundary. The case of liquid phase epitaxial growth of GaAs is considered and an effort for evaluation of the phase boundary extension is undertaken. The linear dependence of the stationary growth rate on the cooling rate, predicted previously, is proved experimentally.
Dilobenol A–G, Diprenylated Dihydroflavonols from the Leaves of Dilobeia thouarsii
Authors: Razafintsalama Vahinalahaja , Girardot Marion , Randrianarivo Ranjana , Rakoto Danielle , Sarter Samira , Petit Thomas , Ralambonirina Sylvia , Deville Alexandre , Grellier Philippe , Jeannoda Victor , Mambu Lengo 
Published: February 2013

AbstractThe study of the EtOAc extract of the leaves of Dilobeia thouarsii led to the isolation and identification of seven new diprenylated dihydroxyflavonols named dilobenol A–G (1–7). Their structures were elucidated by spectroscopic analysis including UV, IR, 1D and 2D NMR and MS as well as by chemical hydrolysis. The isolated compounds were assessed for their antibacterial, antiplasmodial and cytotoxic activities. They exhibited moderate growth inhibitory activities against Staphylococcus aureus, Vibrio spp., Bacillus spp, and Plasmodium falciparum without significant toxicity against mammalian cell line L‐6.
Allium ursinum L. in Germany – surprisingly low genetic variability
Authors: Herden Tobias , Neuffer Barbara , Friesen Nikolai 
Published: February 2013

AbstractAllium ursinum s.l. is a widely spread species of the herb layer in beech forests throughout Europe. Little is known about its phylogenetic origin and its biogeographic history. Molecular genetic analyses of eleven populations from Germany were used to clarify the relationship between populations of A. ursinum s.l. and its relationship to several other species of the genus Allium. The study focused mainly on the Teutoburg Forest in Lower Saxony and the Franconian mountain area in Bavaria. Sequences of the nuclear internal transcribed spacer ITS, and the external transcribed spacer ETS, as well as the plastidic trn L‐rpl 32 and the trn L‐trn F spacer regions were compared. No variation was detected within the species. Even sequences of populations from Belfast, Ireland did not differ from populations of Germany. The closest relative to Allium ursinum s.l. turned out to be Allium moly or Allium scorzonerifolium from the section Molium. Random amplified polymorphic DNA fingerprinting was performed and revealed 29% polymorphic bands. Genetic distances of the populations within the Teutoburg Forest coincided with geographical distances. Three populations (Osnabrück Westerberg, Osnabrück Honeburg and Leer, East Frisia) out of eleven analysed populations were identified as garden escapes. (© 2012 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
The anatomy of recent large sea level fluctuations in the Mediterranean Sea
Authors: Landerer Felix W. , Volkov Denis L. 
Published: February 2013

AbstractDuring the boreal winter months of 2009/2010 and 2010/2011, Mediterranean mean sea level rose 10 cm above the average monthly climatological values. The non‐seasonal anomalies were observed in sea surface height (from altimetry), as well as ocean mass (from gravimetry), indicating they were mostly of barotropic nature. These relatively rapid basin‐wide fluctuations occurred over time scales of 1–5 months. Here we use observations and re‐analysis data to attribute the non‐seasonal sea level and ocean mass fluctuations in the Mediterranean Sea to concurrent wind stress anomalies over the adjacent subtropical Northeast Atlantic Ocean, just west of the Strait of Gibraltar, and extending into the strait itself. The observed Mediterranean sea level fluctuations are strongly anti‐correlated with the monthly North‐Atlantic‐Oscillation (NAO) index.
Rapid computation of sodium bioscales using gpu‐accelerated image reconstruction
Authors: Atkinson Ian C. , Liu Geng , Obeid Nady , Thulborn Keith R. , Hwu Wen‐mei 
Published: February 2013

AbstractQuantitative sodium magnetic resonance imaging permits noninvasive measurement of the tissue sodium concentration (TSC) bioscale in the brain. Computing the TSC bioscale requires reconstructing and combining multiple datasets acquired with a non‐Cartesian acquisition that highly oversamples the center ofk‐space. Even with an optimized implementation of the algorithm to compute TSC, the overall processing time exceeds the time required to collect data from the human subject. Such a mismatch presents a challenge for sustained sodium imaging to avoid a growing data backlog and provide timely results. The most computationally intensive portions of the TSC calculation have been identified and accelerated using a consumer graphics processing unit (GPU) in addition to a conventional central processing unit (CPU). A recently developed data organization technique called Compact Binning was used along with several existing algorithmic techniques to maximize the scalability and performance of these computationally intensive operations. The resulting GPU+CPU TSC bioscale calculation is more than 15 times faster than a CPU‐only implementation when processing 256 × 256 × 256 data and 2.4 times faster when processing 128 × 128 × 128 data. This eliminates the possibility of a data backlog for quantitative sodium imaging. The accelerated quantification technique is suitable for general three‐dimensional non‐Cartesian acquisitions and may enable more sophisticated imaging techniques that acquire even more data to be used for quantitative sodium imaging. © 2013 Wiley Periodicals, Inc. Int J Imaging Syst Technol, 23, 29–35, 2013.
Correlates of bone microarchitectural parameters and serum sclerostin levels in men: The STRAMBO study
Authors: Szulc Pawel , Boutroy Stéphanie , Vilayphiou Nicolas , Schoppet Michael , Rauner Martina , Chapurlat Roland , Hamann Christine , Hofbauer Lorenz C 
Published: February 2013

ABSTRACT

Sclerostin is predominantly expressed by osteocytes. Serum sclerostin levels are positively correlated with areal bone mineral density (aBMD) measured by dual-energy X-ray absorptiometry (DXA) and bone microarchitecture assessed by high-resolution peripheral quantitative computed tomography (HR-pQCT) in small studies. We assessed the relation of serum sclerostin levels with aBMD and microarchitectural parameters based on HR-pQCT in 1134 men aged 20 to 87 years using multivariable models adjusted for confounders (age, body size, lifestyle, comorbidities, hormones regulating bone metabolism, muscle mass and strength). The apparent age-related increase in serum sclerostin levels was faster before the age of 63 years than afterward (0.43 SD versus 0.20 SD per decade). In 446 men aged ≤63 years, aBMD (spine, hip, whole body), trabecular volumetric BMD (Tb.vBMD), and trabecular number (Tb.N) at the distal radius and tibia were higher in the highest sclerostin quartile versus the three lower quartiles combined. After adjustment for aBMD, men in the highest sclerostin quartile had higher Tb.vBMD (mainly in the central compartment) and Tb.N at both skeletal sites (p &lt; 0.05 to 0.001). In 688 men aged &gt;63 years, aBMD was positively associated with serum sclerostin levels at all skeletal sites. Cortical vBMD (Ct.vBMD) and cortical thickness (Ct.Th) were lower in the first sclerostin quartile versus the three higher quartiles combined. Tb.vBMD increased across the sclerostin quartiles, and was associated with lower Tb.N and more heterogeneous trabecular distribution (higher Tb.Sp.SD) in men in the lowest sclerostin quartile. After adjustment for aBMD, men in the lowest sclerostin quartile had lower Tb.vBMD and Tb.N, but higher Tb.Sp.SD (p &lt; 0.05 to 0.001) at both the skeletal sites. In conclusion, serum sclerostin levels in men are strongly positively associated with better bone microarchitectural parameters, mainly trabecular architecture, regardless of the potential confounders.
Cytological observations of the ovarian epithelium in mammals during the reproductive cycle
Authors: Anderson Everett , Lee Gloria , Letourneau Richard , Albertini David F. , Meller Samuel M. 
Published: February 2013

AbstractWe have studied the ovarian epithelium at various stages of the reproductive cycle in a number of mammalian species utilizing light microscopy, scanning microscopy, the freeze‐fracture technique, transmission microscopy and by employing specialized tracers that use lanthanum and horseradish peroxidase. We found that the epithelial cells are joined by incomplete tight junctions, gap junctions, and desmosomes. The cytoplasmic matrix contains a large irregularly shaped nucleus, few microtubules, microfilaments, mitochondria, endoplasmic reticulum and a host of coated and non‐coated vesicles of varying diameters. The saccules comprising the large Golgi complex and its companion vesicles are associated with a basal body‐centriole complex: some of these saccules and affiliated vesicles are acid phosphatase positive.Surface modifications of ovarian epithelial cells include numerous microvilli, some of which have a bulbous tip, and plications of the lateral plasma membrane which are thought to accommodate volume changes of the ovary during follicular development. Many coated and non‐coated endocytotic caveolae were found on these cells, particularly in the basal area. These caveolae internalized exogeneously administered horseradish peroxidase. We view the marked endocytotic activity as an efficient transport mechanism for partially removing substances from the interstitium of the ovary and the peritoneum.
Ultrastructure of the secretory cells of the submucosal glands in the human maxillary sinus
Authors: Vidić Branislav , Tandler Bernard 
Published: February 2013

AbstractTissue samples obtained from the lateral wall of the maxillary sinuses of five patients were examined by light microscopical, histochemical, and ultrastructural techniques. Submucosal glands were tubulo‐alveolar mixed glands. The acini consisted of either all serous or all mucous cells, or a mixture of both. Serous granules were stained by toluidine blue, or by hematoxylin and eosin (H and E), but showed little or no reaction with periodic acid‐Schiff (PAS) or Alcian blue. Mucous granules were pale in toluidine blue or H and E preparations, and consisted primarily of acid mucosubstances, as demonstrated by their staining reaction with PAS and Alcian blue. At the electron microscope level, the serous granules were either homogeneously dense, or showed a substructure consisting of at least two layers of distinctly different electron‐opacity. Typical mucous droplets consisted of a fibrillar network dispersed in a translucent matrix. A second secretory product was present in the mucous cells in the form of elongated, membrane‐bounded structures containing numerous parallel filaments, which measured about 55 Å in diameter. The mucous droplets and the filamentous bodies appear to arise from the opposite faces of the Golgi complex in the mucous cells. The filamentous bodies showed a pronounced tendency to fuse with the mucous droplets. All acini were surrounded by a well‐defined myoepithelial layer and contained intercellular nerve terminals.