bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hypoglossal canal dural arteriovenous fistula: incidence and the relationship between symptoms and drainage pattern
Authors: Choi Jong Won , Kim Byung Moon , Kim Dong Joon , Kim Dong Ik , Suh Sang Hyun , Shin Na-Young , Lee Jin Goo 
Published: May 2013

Object
The purpose of this study was to evaluate the incidence, radiographic findings, relationship between presenting symptoms for treatment and drainage pattern, and treatment outcomes of hypoglossal canal dural arteriovenous fistula (HC-dAVF).

Methods
During a 16-year period, 238 patients underwent endovascular treatment for cranial dAVF at a single center. The incidence, radiographic findings, relationship between presenting symptoms for treatment and drainage pattern, and treatment outcomes of HC-dAVF were retrospectively evaluated.

Results
The incidence of HC-dAVF was 4.2% (n = 10). Initial symptoms were tinnitus with headache (n = 6), tinnitus only (n = 1), ocular symptoms (n = 1), otalgia (n = 1), and congestive myelopathy (n = 1). Presenting symptoms requiring treatment included ocular symptoms (n = 4), hypoglossal nerve palsy (n = 4), aggravation of myelopathy (n = 1), and aggravation of tinnitus with headache (n = 1). While the affected HC was widened in 4 of 10 patients, hypersignal intensity on source images was conspicuous in all 7 patients who underwent MR angiography (MRA). All ocular symptoms and congestive myelopathy were associated with predominant drainage to superior ophthalmic or perimedullary veins due to antegrade drainage restriction. All patients who underwent transvenous coil embolization (n = 8) or transarterial N-butyl cyanoacrylate (NBCA) embolization (n = 1) improved without recurrence. One patient who underwent transarterial particle embolization had a recurrence 12 months posttreatment and was retreated with transvenous embolization.

Conclusions
The incidence of HC-dAVF was 4.2% of all cranial dAVF patients who underwent endovascular treatment. Source images of MRA helped to accurately diagnose HC-dAVF. More aggressive symptoms may develop as a result of a change in the predominant drainage route due to the development of venous stenosis or obstruction over time. Transvenous coil embolization appears to be the first treatment of choice.
La dynamique des taux de chômage, de destruction et de retour à l'emploi
Authors: Abeille-Becker Camille , Clerc Pierrick 
Published: May 2013

Nous déterminons un étalonnage permettant au modèle d’appariement de reproduire la volatilité du taux de chômage ainsi que celle de ses deux composantes, le taux de retour à l’emploi et le taux de destruction d’emplois. Nous mettons en exergue un mécanisme central de ce modèle : l’introduction de destructions cycliques amplifie la volatilité du taux de retour à l’emploi. Ce mécanisme implique que ce modèle ne nécessite pas d’avoir recours à des rigidités du salaire réel et que la valeur du coût d’opportunité de l’emploi nécessaire à la reproduction des différentes volatilités soit moins élevée que dans le modèle à destructions constantes et donc plus plausible.
ImPact Test-Retest Reliability: Reliably Unreliable?
Authors: Resch Jacob , Driscoll Aoife , McCaffrey Noel , Brown Cathleen , Ferrara Michael S. , Macciocchi Stephen , Baumgartner Ted , Walpert Kimberly 
Published: May 2013

Context:
Computerized neuropsychological testing is commonly used in the assessment and management of sport-related concussion. Even though computerized testing is widespread, psychometric evidence for test-retest reliability is somewhat limited. Additional evidence for test-retest reliability is needed to optimize clinical decision making after concussion.

Objective:
To document test-retest reliability for a commercially available computerized neuropsychological test battery (ImPACT) using 2 different clinically relevant time intervals.

Design:
Cross-sectional study.

Setting:
Two research laboratories.

Patients or Other Participants:
Group 1 (n = 46) consisted of 25 men and 21 women (age = 22.4 ± 1.89 years). Group 2 (n = 45) consisted of 17 men and 28 women (age = 20.9 ± 1.72 years).

Intervention(s):
Both groups completed ImPACT forms 1, 2, and 3, which were delivered sequentially either at 1-week intervals (group 1) or at baseline, day 45, and day 50 (group 2). Group 2 also completed the Green Word Memory Test (WMT) as a measure of effort.

Main Outcome Measures:
Intraclass correlation coefficients (ICCs) were calculated for the composite scores of ImPACT between time points. Repeated-measures analysis of variance was used to evaluate changes in ImPACT and WMT results over time.

Results:
The ICC values for group 1 ranged from 0.26 to 0.88 for the 4 ImPACT composite scores. The ICC values for group 2 ranged from 0.37 to 0.76. In group 1, ImPACT classified 37.0% and 46.0% of healthy participants as impaired at time points 2 and 3, respectively. In group 2, ImPACT classified 22.2% and 28.9% of healthy participants as impaired at time points 2 and 3, respectively.

Conclusions:
We found variable test-retest reliability for ImPACT metrics. Visual motor speed and reaction time demonstrated greater reliability than verbal and visual memory. Our current data support a multifaceted approach to concussion assessment using clinical examinations, symptom reports, cognitive testing, and balance assessment.
Association of psychiatric co.morbidity and efficacy of treatment in chronic daily headache in Indian population
Authors: Singh Ajai Kumar , Shukla Rakesh , Trivedi Jitendra Kumar , Singh Deepti 
Published: May 2013

ABSTRACTObjective: To study the prevalence of psychiatric co‑morbidity in patients of chronic daily headache (CDH) and compare the efficacy of treatment between various type of headache associated with psychiatric co‑morbidity. Materials and Methods: Prospective case control cohort study, 92 consecutive patients of CDH meeting eligibility criteria. The diagnosis of various subtypes of CDH was made according to the IHS criteria. Age, sex, educational, marital and socioeconomic status, matched controls were also selected. Patients were evaluated with the Mini International Neuropsychiatric Interview (MINI) scale at the time of enrolment and at 3 months. Results: CDH accounted for 28% of all headache patients. The mean age of presentation was 30.2 ± 10.3 years, male: Female ratio of 28:64 and mean duration of 4.56 ± 0.56 years. Chronic migraine (CM) accounted for 59 patients, chronic tension type headache (CTTH) 22 patients, new daily persistent headache (NDPH) 3 patients and miscellaneous 8 patients. Psychiatric co‑morbidity was present in 53.3% patients with CDH, and was more common in CM (62.7%) as compared to CTTH (36.4%). Single psychiatric co‑morbidity was seen in 26 patients, while 23 patients had multiple co‑morbidity. Major depressive episode, anxiety disorder, agoraphobia and dysthymia were significant psychiatric co‑morbidities. Patients with CM were treated with topiramate or divalproex sodium ER and CTTH were treated with amitriptyline. 55 patients came for follow up at 3 months, improvement in headache was seen in 29 patients. Conclusion: Psychiatric co‑morbidity was present in more than 50% patients with CDH and its presence along with a duration of ≥2 years was associated with a poor response to treatment.
Infratentorial subdural empyemas mimicking pyogenic meningitis
Authors: Gupta Anurag , Karanth Suman S , Raja A 
Published: May 2013

ABSTRACTInfratentorial subdural empyema is an extremely rare condition which unfortunately mimics pyogenic meningitis in 75% of cases. While an ill‑planned lumbar puncture in these cases may be fatal, an inadvertent delay in treatment may be detrimental to the outcome for the patient. We present a case of a young boy with long standing history of chronic suppurative otitis media (CSOM) presenting with an infratentorial empyema with features suggestive of pyogenic meningitis. We also review the available literature to further define the condition in terms of clinical features, treatment options, and outcome. A misdiagnosis of this condition with failure to institute appropriate surgical intervention and antibiotic therapy is potentially life threatening. We highlight this rare condition which requires a high degree of suspicion especially in the presence of associated risk factors.
Deletion pattern in the dystrophin gene in Duchenne muscular dystrophy patients in northeast India
Authors: Basumatary Lakshya J , Das Marami , Goswami Munindra , Kayal Ashok K 
Published: May 2013

ABSTRACTDuchenne muscular dystrophy (DMD) is an X‑linked recessive disorder that affects 1 in 3,500 males and is caused by mutations in the dystrophin gene. In this paper, we have reported DNA analysis of DMD patients by multiplex polymerase chain reaction (PCR) from various states of northeast India. Of the 69 clinically suspected patients of DMD, deletion was detected by multiplex PCR in 49 (71%) patients. Majority of the deletions (42/49, 85.7%) were located at distal hot spot region that encompasses exons 44-55 and 14.3% of the deletions were located at the proximal hot spot region (exons 2-19). In this study population, the deletion rate was 71% and was more frequent in the distal end exon.
Bedside Sonography for Detection of Postprocedure Pneumothorax
Authors: Shostak Eugene , Brylka Douglas , Krepp Joseph , Pua Bradley , Sanders Abraham 
Published: May 2013

ObjectivesBedside sonography for diagnosis of pneumothorax has been well described in emergency and trauma medicine literature. Its role in detection of iatrogenic pneumothorax has not been well studied. We describe the performance of bedside sonography for detection of procedure‐related pneumothorax and highlight some limitations.MethodsA total of 185 patients underwent thoracentesis (n = 60), transbronchial biopsy (n = 48), and computed tomography–guided needle lung biopsy (n = 77). Bedside preprocedure and postprocedure transthoracic sonography and postprocedure chest radiograph were performed in all patients. Patients in whom the pleural surface was not well imaged with sonography were said to have a limited examination. Chest radiography was the standard for diagnosing pneumothorax.ResultsChest radiography showed pneumothorax in 8 of 185 patients (4.0%). These patients had undergone computed tomography–guided needle lung biopsy (n = 7) and transbronchial needle lung biopsy (n = 1). Sonography showed pneumothorax in 7 of these patients. The sensitivity, specificity, and diagnostic accuracy were 88%, 97%, and 97%, respectively. Limited‐quality sonographic examinations due to preexisting lung disease were seen in 43 of 185 patients. The positive and negative likelihood ratios for patients with adequate scans were 55 and 0.17, respectively. The likelihood ratio for patients with limited‐quality scans was 1.08.ConclusionsWhen a good‐quality scan is achieved, bedside chest sonography is a valuable tool for evaluation of postprocedure pneumothorax. Patients with preexisting lung disease, in whom the quality of the sonographic examination is limited, should be studied with chest radiography.
Distribution and characteristics of occupational injuries and diseases among farmers: A retrospective analysis of workers' compensation claims
Authors: Karttunen Janne P. , Rautiainen Risto H. 
Published: May 2013

AbstractBackgroundResearch indicates occupational injuries and diseases are not evenly distributed among workers. We investigated the distribution and characteristics of compensated occupational injuries and diseases requiring medical care in the Finnish farming population.MethodsThe study population consisted of 93,564 Finnish farmers, spouses, and salaried family members who were covered by the mandatory workers' compensation insurance in 2002. This population had a total of 133,207 occupational injuries and 9,148 occupational diseases over a 26‐year period (1982–2008).ResultsClustering of claims was observed. Nearly half (47.1%) of the population had no compensated claims while 52.9% had at least one; 50.9% of farmers had one or more injuries and 8.1% had one or more diseases. Ten percent of the population had half of injury cases, and 3% of the population had half of occupational disease cases. Claims frequently involved work tasks related to animal husbandry and repair and maintenance of farm machinery. Injury and disease characteristics (work activity, cause, ICD‐10 code) differed between individuals with high and low personal claim rate. Injuries and diseases of the musculoskeletal system had a tendency to reoccur among those with high claim rate. These outcomes were often related to strenuous working motions and postures in labor‐intensive animal husbandry.ConclusionsAnalyses of longitudinal insurance data contributes to better understanding of the long‐term risk of occupational injury and disease among farmers. We suggest focusing on recurrent health outcomes and their causes among high risk populations could help design more effective interventions in agriculture and other industries. Am. J. Ind. Med. 56:856–869, 2013. © 2013 Wiley Periodicals, Inc.
Natural history and parental experience of children with trisomy 18 based on a questionnaire given to a Japanese trisomy 18 parental support group
Authors: Kosho Tomoki , Kuniba Hideo , Tanikawa Yuko , Hashimoto Yoko , Sakurai Hiroko 
Published: May 2013

AbstractWe conducted a questionnaire‐based study in collaboration with a Japanese trisomy 18 parental support group. Sixty‐five children (female, 68%) with full trisomy 18 were evaluated. Diagnosis was made prenatally in 17% (11/65) and 57% (37/65) were born following a cesarean. The mean gestational age at delivery was 38 weeks and 6 days, and the mean birth weight was 1,920 g (−2.6SD). A total of 51% (24/47) of children had apneic episodes. Thirteen children experienced generalized seizures, and a minority was seizure‐free with medication. Parents of 36% (18/50) of children were offered intensive treatment. A total of 45% (27/60) of children received intermittent mandatory ventilation, which was weaned off in half of them. Nine had surgeries, including esophageal atresia/omphalocele correction, cardiac surgery, and tracheostomy. A total of 15% (8/55) were fed fully orally, and 45% (29/64) were discharged home. Slow but constant psychomotor development was observed, and in four long‐term survivors over 10 years, two walked unassisted. Factors significantly associated with survival over 1 year included diagnosis after birth, absence of prematurity, heavier birth weight, absence of esophageal atresia, extubation, ability to feed orally without medical assistance, and home discharge. Parents appeared to be positive about caring for their children, and the children seemed to interact with parents and siblings as long as they lived, resulting in quality family time. The family point of view, as well as knowledge of natural history, should be considered when policy statements about the care of children with trisomy 18 are made. © 2013 Wiley Periodicals, Inc.
Design and synthesis of water‐soluble photosensitive α‐cyclodextrin and its application in dispersing carbon nanotubes
Authors: Liu Jingcheng , Liu Ren , Jiang Jinqiang , Liu Xiaoya 
Published: May 2013

ABSTRACTThis manuscript describes the use of a novel water‐soluble photosensitive α‐cyclodextrin modified coumarin (α‐CD‐C) to disperse carbon nanotubes (CNTs) in water. First, using epichlorohydrin as the bridged unit, water‐soluble α‐cyclodextrin (α‐CD) was introduced to modify 7‐hydroxy‐4‐methylcoumarin and prepare α‐CD‐C. α‐CD‐C was characterized with hydrogen nuclear magnetic resonance spectra (1H‐NMR) and High pressure liquid chromatography‐mass spectrometry. The photodimerization experiment showed that α‐CD‐C could photodimerize upon 365 nm irradiation, and then photo‐de‐crosslink upon the subsequent 254 nm irradiation. Next, α‐CD‐C was used to disperse CNTs in water. Transmission electron microscope and scanning electron microscope demonstrated that α‐CD‐C effectively adsorbed onto the surface of CNTs. The α‐CD‐C is an efficient dispersant for CNTs. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 130: 2588–2593, 2013
Active Mode Recognition of Switched Nonlinear Systems: Application to Fault Detection and Isolation
Authors: Zouari Talel , Pekpe Komi Midzodzi , Cocquempot Vincent , Ksouri Moufida 
Published: May 2013

AbstractRobust switching detection and active mode recognition are addressed for switched nonlinear systems. The nonlinear modes are represented by Takagi‐Sugeno (TS) models where the weighting functions are supposed to be online computable. The proposed switching detection technique and the active mode recognition method lie on indicator signals that are generated using a data‐driven projection technique. The main advantage of this method is that it does not need the knowledge of local model parameter values. Only input‐output data and the weighting functions of the TS model are used to generate these indicator signals. A numerical example is provided to illustrate the proposed approach.
Basic Design Concept of a Microreactor for Isothermal Operation Including Heat Conductivity
Authors: Fukuda T. , Sawada M. , Maki T. , Mae K. 
Published: May 2013

AbstractA method for designing microreactors for isothermal operation with multiple highly exothermic or endothermic reactions under the conditions of fluid flow in a laminar flow state between two parallel plates is discussed. The formulated design procedure is based on a correlation between the fluid conditions and the heat properties; the operational conditions required for, e.g., a desired heat removal rate can be observed using the provided contour charts. The applicability of the proposed design method was verified using computational fluid dynamics simulations. In addition, the superiority of the microreactors is discussed specifically on the basis of the knowledge from the created charts.
An Insight to Chiral Monolith for Enantioselective Nano and Micro HPLC: Preparation and Applications
Authors: Healey Robert , Ghanem Ashraf 
Published: May 2013

ABSTRACTThis review gives an overview of chiral separation principles and their application in enantioselective nano/micro high performance liquid chromatography (n/μ‐HPLC) using chiral monolith. In particular, developments in silica and polymer chiral monolithic stationary phases are presented. The preparation and applications of chiral monoliths, the basic chiral separation principles and the mechanisms are discussed. Chirality 25:314–323, 2013. © 2013 Wiley Periodicals, Inc.
Optical Purifications via Self‐Disproportionation of Enantiomers by Achiral Chromatography: Case Study of a Series of α‐CF3‐containing Secondary Alcohols
Authors: Sorochinsky Alexander E. , Katagiri Toshimasa , Ono Taizo , Wzorek Alicja , Aceña José Luis , Soloshonok Vadim A. 
Published: May 2013

ABSTRACTThis work demonstrates that self‐disproportionation of enantiomers via achiral chromatography can be recommended as inexpensive and general method for optical purification of enantiomerically enriched compounds. In particular, the advantage of this approach over conventional recrystallization is that it can be used for both crystalline as well as liquid compounds. Chirality, 25:365‐368, 2013. © 2013 Wiley Periodicals, Inc.
Extended Model for Theoretical Determination of Mass Transfer Coefficients in Multiphase Flows – Part 2
Authors: John Saskia , Dujardin Viviane , Kück Ulf Daniel , Mießner Ulrich , Räbiger Norbert 
Published: May 2013

AbstractDie Auslegung von Reaktoren mit Mehrphasensystemen und chemischer Reaktion stellt auch heute noch eine Herausforderung dar. Neue, erweiterte Erkenntnisse über die in Mehrphasenströmungen auftretenden örtlichen Transportprozesse weisen vielversprechende Optionen in Hinblick auf eine theoretische Abschätzung von Stoffübergangskoeffizienten auf. Ein auf den neuen Erkenntnissen basierender Modellansatz zur Berechnung des Stofftransportkoeffizienten wurde im ersten Teil dieser Veröffentlichung aufgezeigt und wird im vorliegenden Artikel hinsichtlich der Relevanz für die praxisrelevante Auslegung von Treibstrahl‐Schlaufenreaktoren überprüft.
Multicomponent Domino [4+1+1] Carbocyclization Providing an Efficient and Regioselective Strategy to Fluoren‐9‐ones
Authors: Li Ying , Xu Haiwei , Fu Liping , Shi Qingqing , Jiang Bo , Tu Shujiang 
Published: May 2013

AbstractConcise and efficient three‐component domino [4+1+1] carbocyclization to highly substituted fluoren‐9‐one derivatives promoted by K2CO3 has been developed under microwave irradiation conditions. The direct bis‐cyanation and aryl amination residing in fluoren‐9‐one framework were achieved in a one‐pot operation. The reaction proceeds at fast rates and can be finished within 30 min, which makes workup convenient to give good to excellent chemical yields.
Clinical predictors of survival in men with castration‐resistant prostate cancer
Authors: Nakabayashi Mari , Hayes Julia , Taplin Mary‐Ellen , Lefebvre Patrick , Lafeuille Marie‐Helene , Pomerantz Mark , Sweeney Christopher , Duh Mei Sheng , Kantoff Philip W. 
Published: May 2013

BACKGROUNDThis study sought to characterize Modern patients with castration‐resistant prostate cancer (CRPC) and identify pretreatment clinical predictors of survival.METHODSA cohort of men with CRPC with and without metastases (M) treated with secondary hormonal therapy (2eHT) and/or chemotherapy (CT) was identified from the authors' institutional database. Associations of patient and disease characteristics at diagnosis, at androgen‐deprivation therapy (ADT) initiation, at CRPC index date, and survival were evaluated. CRPC index date was defined as the start date of either 2eHT or CT, whichever came first.RESULTSIn the cohort of 622 men, 434 men (70%) had M‐positive disease; 552 men (89%) received 2eHT and 70 men (11%) received CT as their initial CRPC treatment. There were 410 deaths (66%) at the time of analysis. Median overall survival (OS) was 35 months (quartile 1, quartile 3: 21 months, 61 months). In multivariate analyses, higher biopsy Gleason score, the presence of M at ADT initiation, shorter time from ADT start to CRPC, higher prostate‐specific antigen and poorer Eastern Cooperative Oncology Group performance status at CRPC and M at CRPC were predictive of shorter OS. Interestingly, whereas some men with biopsy Gleason scores of 6 died of their disease (N = 42), they had a longer OS after CRPC compared with those with a Gleason score ≥ 7.CONCLUSIONSThis large retrospective study of patients with CRPC in a tertiary cancer center shows that biopsy Gleason score of 6 is associated with a less aggressive CRPC course, and the impact that M at ADT initiation and CRPC have on outcome is quantified. Cancer 2013;119:2990—2998. © 2013 American Cancer Society.