bluuebunny/crossref_metadata_2025_split huggingface dataset:
Awake mapping for low-grade gliomas involving the left sagittal stratum: anatomofunctional and surgical considerations
Authors: Chan-Seng Emilie , Moritz-Gasser Sylvie , Duffau Hugues 
Published: January 2014

Object
Preserving function while optimizing the extent of resection is the main goal in surgery for diffuse low-grade glioma (DLGG). This is particularly relevant for DLGG involving the sagittal stratum (SS), where damage can have severe consequences. Indeed, this structure is a major crossroad in which several important fascicles run. Thus, its complex functional anatomy is still poorly understood. Subcortical electrical stimulation during awake surgery provides a unique opportunity to investigate white matter pathways. This study reports the findings on anatomofunctional correlations evoked by stimulation during resection for gliomas involving the left SS. Surgical outcomes are also detailed.

Methods
The authors performed a review of patients who underwent awake surgery for histopathologically confirmed WHO Grade II glioma involving the left SS in the neurosurgery department between August 2008 and August 2012. Information regarding clinicoradiological features, surgical procedures, and outcomes was collected and analyzed. Intraoperative electrostimulation was used to map the eloquent structures within the SS.

Results
Eight consecutive patients were included in this study. There were 6 men and 2 women, whose mean age was 41.7 years (range 32–61 years). Diagnosis was made because of seizures in 7 cases and slight language disorders in 1 case. After cortical mapping, subcortical stimulation detected functional fibers running in the SS in all patients: semantic paraphasia was generated by stimulating the inferior frontooccipital fascicle in 8 cases; alexia was elicited by stimulating the inferior longitudinal fascicle in 3 cases; visual disorders were induced by stimulating the optic radiations in 5 cases. Moreover, in front of the SS, phonemic paraphasia was evoked by stimulating the temporal part of the arcuate fascicle in 5 patients. The resection was stopped according to these functional limits in the 8 patients. After a transient postsurgical worsening, all patients recovered to normal results on examination, except for the persistence of a right superior quadrantanopia in 5 cases, with no consequences for quality of life. The 8 patients returned to a normal social and professional life. Total or subtotal resection was achieved in all cases but one.

Conclusions
The authors suggest that the use of intrasurgical electrical mapping of the white matter pathways in awake patients opens the door to extensive resection of DLGG within the left SS while preserving the quality of life. Further anatomical, clinical, radiological, and electrophysiological studies are needed for a better understanding of the functional anatomy of this complex region.
Effect of mixing techniques on bacterial attachment and disinfection time of polyether impression material
Authors: Guler Umut , Budak Yasemin , Ruh Emrah , Ocal Yesim , Canay Senay , Akyon Yakut 
Published: January 2014

ABSTRACT
Objective: The aim of this study was 2-fold. The first aim was to evaluate the effects of mixing technique (hand-mixing or auto-mixing) on bacterial attachment to polyether impression materials. The second aim was to determine whether bacterial attachment to these materials was affected by length of exposure to disinfection solutions. Materials and Methods: Polyether impression material samples (n = 144) were prepared by hand-mixing or auto-mixing. Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa were used in testing. After incubation, the bacterial colonies were counted and then disinfectant solution was applied. The effect of disinfection solution was evaluated just after the polymerization of impression material and 30 min after polymerization. Differences in adherence of bacteria to the samples prepared by hand-mixing and to those prepared by auto-mixing were assessed by Kruskal-Wallis and Mann-Whitney U-tests. For evaluating the efficiency of the disinfectant, Kruskal-Wallis multiple comparisons test was used. Results: E. coli counts were higher in hand-mixed materials (p < 0.05); no other statistically significant differences were found between hand- and auto-mixed materials. According to the Kruskal-Wallis test, significant differences were found between the disinfection procedures (Z > 2.394). Conclusions: The methods used for mixing polyether impression material did not affect bacterial attachment to impression surfaces. In contrast, the disinfection procedure greatly affects decontamination of the impression surface.
Effect of operator variability on microleakage with different adhesive systems
Authors: Karaman Emel , Yazici A. Ruya , Aksoy Burak , Karabulut Erdem , Ozgunaltay Gul , Dayangac Berrin 
Published: January 2014

ABSTRACTObjective: The objective of this study was to evaluate the effect of operator variability on microleakage with different adhesive systems. Materials and Methods: A total of 180 standardized Class V cavities were prepared on facial and lingual of 90 extracted human premolar teeth and randomly assigned to five groups according to the adhesive systems used (n = 36): Prime and Bond NT (PB), Single Bond (SB), Futura Bond NR, Xeno III (XE) and Adper Prompt-L-Pop (LP). The adhesive groups were then further subdivided into three operator groups according to level of clinical experience (n = 12): An undergraduate student, a research assistant and a faculty member. All cavities were restored with same composite resin. The restored teeth were thermocycled (500 cycles, 5-55°C) then immersed in 0.5% basic fuchsin and measured for leakage under a stereomicroscope. Statistical analyses were performed with the Kruskal-Wallis and Mann-Whitney U tests. Results: Significant inter-operator variation was found in the enamel margins in the XE group with significantly higher microleakage when used by the undergraduate student (p < 0.05). Although no significant differences in microleakage were found between adhesive systems for the research assistant and faculty member (p > 0.05), significant differences were observed between PB and LP, PB and XE, SB and LP and SB and XE in the enamel margins for the undergraduate student (p < 0.05). Conclusions: Microleakage of adhesive systems is more dependent on interactions between the operator and adhesive material than on the choice of adhesive material.
Isolated oligodontia in monozygotic twins
Authors: Halicioglu Koray , Sahin Hakan , Corekci Bayram , Irgin Celal , Toptas Orcun 
Published: January 2014

ABSTRACTThis case report defines a case of isolated oligodontia of 9 and 10 permanent teeth in 9-year-old monozygotic twin sisters and gives information about the possible genetic and environmental etiology, related dental anomalies and treatment options. The twins have a negative family history of hypodontia and oligodontia in their parents, as well as their paternal and maternal grandmothers and first cousins. No other dental anomalies could be detected in either of the twins. With the occurrence of similarly located tooth agenesis, except for one tooth, in monozygotic twins, one may consider the influence of genetic and/or environmental factors in their etiology. Hereditary relationships associated with oligodontia could help the clinicians to predict the possibility of its occurrence in other family members and in the next generations. However, clinicians should consider oligodontia when it is not hereditary.
Can dentin surfaces be bonded safely with total-etch and self-etch systems?
Authors: Akin Mehmet , Baka Zeliha Muge , Ileri Zehra , Basciftci Faruk Ayhan 
Published: January 2014

Abstract
Objective: To assess and compare the shear bond strengths (SBSs) of orthodontic brackets bonded to enamel and dentin surfaces by using total-etching and 3 different self-etching adhesives. Materials and Methods: A total of 160 extracted mandibular incisors were randomly divided into 4 groups. In Group I, the hard tissue was etched with 37% phosphoric acid; in Group II, Transbond Plus Self Etching Primer (TSEP) system was used; in Group III, Clearfil Tri-S Bond Plus was used; and, in Group IV, AdheSE was used. Each group was divided into 2 subgroups: The enamel surfaces were conditioned in subgroup-A, and the dentin surfaces were conditioned in subgroup-B. The samples were stored in water for 24 h at 37°C and then thermocycled. The SBS in megapascals (MPa) was determined by a shear test with 0.5 mm/min crosshead speed, and failure types were classified with modified adhesive remnant index (ARI) scores. The data were analyzed with two-way analyses of variance, Tukey′s, and Chi-square tests at the 0.05 level. Results: The mean SBS value of subgroup-A in Group I was significantly higher than the mean values in the other groups (P<0.05). There were no significant differences among the SBS values in the other groups (P>0.05). Significant differences were found in the ARI between subgroup-A in Group I and the other groups (P<0.001). Conclusions: When used on the enamel, the self-etch systems did not have bond strengths as high as that in the conventional method. However, the self-etch systems can be used as successfully as the conventional method on dentin surfaces.
O PDCA como ferramenta de apoio à implementação do planejamento estratégico em uma instituição de ensino
Authors: Zandavalli Carla , Mello Marta Inês Caldart de , Souza Ana Clara Medina Menezes de , Andreolla Veruschka Rocha Medeiros , Jubini Gilberto Mazoco 
Published: January 2014

A presente pesquisa configurar-se como um estudo de caso de caráter qualitativo que tem como objetivo identificar as contribuições que o ciclo PDCA pode trazer na fase de implementação do planejamento estratégico na Instituição de Ensino em estudo. Foram aplicados 17 questionários na área estratégica da Instituição e levantou-se as possíveis contribuições da aplicação do ciclo PDCA nesta fase. O estudo revelou que 64,7 % dos gestores tem formação de curta duração em gestão e nenhum gestor tem graduação na área, sendo que 94,1 % dos gestores adquirem conhecimentos sobre gestão com a prática do dia-a-dia. Observa-se que 94,1 % dos gestores responderam que é “muito importante” a existência de uma ferramenta de apoio na execução da estratégia. Quanto a aplicação do ciclo PDCA, como uma ferramenta de apoio a fase de implementação do PE, observou-se que há contribuições quanto aos procedimentos que facilitem a execução da estratégia, incentivo ao aperfeiçoamento contínuo, apoio a sistemas de informação, acompanhamento da execução da estratégia, necessidade de desdobramento de estratégias e ações entre os níveis da instituição.Não pode ser evidenciado que o método contribui diretamente nas questões relacionadas à estrutura, comunicação, liderança e cultura na organização.
Implementación de la carrera académica como medio de integración del NSPT a la Universidad
Authors: Geromini Noemi Susana , Lovallo Carlo Gustavo 
Published: January 2014

Con el fin de mejorar la calidad académica de su cuerpo docente, el Instituto Nacional Superior del Profesorado Técnico -INSPT-, como Institución de Educación Superior no Universitaria, considera necesaria la planificación de estrategias que permitan generar espacios de pertenencia a sus docentes, que les otorguen estabilidad laboral y posibilidades de proyección, mediante el establecimiento de reglas claras e imparciales que protejan a la comunidad académica. La calidad académica se logra por medio de una clara definición de las características esperadas de los docentes y la excelencia se fomenta con procesos de evaluación continuos de todas las activida-des de la vida académica: enseñanza, investigación, extensión y gestión. La Carrera Académica, sistema que establece ingreso, permanencia y promoción de los docentes, resulta ser el recurso más adecuado para estimular la mejora continua de la tarea docente y lograr la excelencia académica, haciendo posible la integración de una institución no universitaria al sistema universitario. Mediante un exhaustivo análisis de la idiosincrasia de la comunidad educativa del INSPT, y aten-diendo a las características esperables de sus docentes, el Instituto procura adaptarse al régimen docente universitario vigente en la Universidad Tecnológica Nacional -UTN. Para lograr este objetivo, se han analizado el Estatuto Universitario, la Ordenanza 1182 del Consejo Superior y se ha elaborado un documento que, por un lado, fundamenta la necesidad de adecuar el régimen de ingreso, permanencia y promoción docente del INSPT a la Carrera Académica de la Universidad, y por otro, propone los pasos a seguir para su implementación, con el convencimiento de que su aplicación redundará en una continua mejora de la calidad académica del Instituto. El presente trabajo tiene como objetivos, por un lado, fundamentar y describir el proceso de ade-cuación del régimen docente del INSPT, a la Carrera Académica de la UTN, resaltando su valor como medio de integración del Instituto a la Universidad y a la vez, presentar una propuesta de im-plementación de la Carrera Académica al Instituto.
A 0.6 million year record of millennial‐scale climate variability in the tropics
Authors: Gibson Kelly Ann , Peterson Larry C. 
Published: January 2014

AbstractA ~600 kyr long scanning X‐ray fluorescence record of redox variability from the Cariaco Basin, Venezuela, provides insight into rapid climate change in the tropics over the past five glacial‐interglacial cycles. Variations in the sediment accumulation of the redox‐sensitive element molybdenum (Mo) can be linked to changes in Intertropical Convergence Zone migration and reveal that millennial‐scale variability is a persistent feature of tropical climate over the past 600 kyr, including during periods of interglacial warmth. This new record supports the idea that high‐frequency tropical climate variability is not controlled solely by ice volume changes, with implications for the role of high‐latitude forcing of Intertropical Convergence Zone position and tropical hydrology on millennial timescales.
Swiss tree rings reveal warm and wet summers during medieval times
Authors: Kress Anne , Hangartner Sarah , Bugmann Harald , Büntgen Ulf , Frank David C. , Leuenberger Markus , Siegwolf Rolf T.W. , Saurer Matthias 
Published: January 2014

AbstractWe present a 1200 year drought reconstruction for the European Alpine region based on carbon isotope variations of tree rings from living larch trees and historic timber. The carbon isotope fractionation at the study site is sensitive to summer precipitation, temperature, and irradiance, resulting in a stable and high correlation with a drought index for interannual to decadal frequencies and possibly beyond (r2 = 0.58 for 1901–2004, July/August). When combining this information with maximum latewood density‐derived summer temperature, a strongly reduced occurrence of summer droughts during the warm A.D. 900–1200 period is evident, coinciding with the Medieval Climate Anomaly (MCA), with a shift to colder and drier conditions for the subsequent centuries. The warm‐wet MCA contrasts strongly with the climate of the drought‐prone warm phase of the recent decades, indicating different forcing mechanism for these two warm periods and pointing to beneficial conditions for agriculture and human well‐being during the MCA in this region.
Modeling ice‐ocean interaction in ice‐shelf crevasses
Authors: Jordan James R. , Holland Paul R. , Jenkins Adrian , Piggott Matthew D. , Kimura Satoshi 
Published: January 2014

AbstractOcean freezing within ice‐shelf basal crevasses could potentially act as a stabilizing influence on ice shelves; however, ice‐ocean interaction and ocean dynamics within these crevasses are as yet poorly understood. To this end, an idealized 2‐D model of an ice‐shelf basal crevasse has been developed using Fluidity, a finite‐element ocean model using an unstructured mesh. A simple model of frazil ice formation and deposition has been incorporated into Fluidity to better represent the freezing process. Model results show two different flow regimes, dependent on the amount of freezing in the crevasse: one driven by freezing at the top of the crevasse and the other by the ingress of meltwater from outside the crevasse. In the first, freezing at the top of the crevasse leads to the formation of an unstable overturning circulation due to the rejection of dense, salty water. In the second, a buoyant layer is formed along the sides and roof of the crevasse, stratifying the water column. Frazil ice precipitation is found to be the dominant freezing process at the top of the basal crevasse in the freeze‐driven case, with direct freezing being dominant in the melt‐driven case. In both cases, melting occurs lower down on the walls of the crevasse due to the strong overturning circulation. The freezing in ice‐shelf crevasses and rifts is found to be highly dependent upon ocean temperature, providing a stabilizing influence on ice shelves underlain by cold waters that is not present elsewhere.
Configuration and assessment of the GISS ModelE2 contributions to the CMIP5 archive
Authors: Schmidt Gavin A. , Kelley Max , Nazarenko Larissa , Ruedy Reto , Russell Gary L. , Aleinov Igor , Bauer Mike , Bauer Susanne E. , Bhat Maharaj K. , Bleck Rainer , Canuto Vittorio , Chen Yong‐Hua , Cheng Ye , Clune Thomas L. , Del Genio Anthony , de Fainchtein Rosalinda , Faluvegi Greg , Hansen James E. , Healy Richard J. , Kiang Nancy Y. , Koch Dorothy , Lacis Andy A. , LeGrande Allegra N. , Lerner Jean , Lo Ken K. , Matthews Elaine E. , Menon Surabi , Miller Ron L. , Oinas Valdar , Oloso Amidu O. , Perlwitz Jan P. , Puma Michael J. , Putman William M. , Rind David , Romanou Anastasia , Sato Makiko , Shindell Drew T. , Sun Shan , Syed Rahman A. , Tausnev Nick , Tsigaridis Kostas , Unger Nadine , Voulgarakis Apostolos , Yao Mao‐Sung , Zhang Jinlun 
Published: January 2014

AbstractWe present a description of the ModelE2 version of the Goddard Institute for Space Studies (GISS) General Circulation Model (GCM) and the configurations used in the simulations performed for the Coupled Model Intercomparison Project Phase 5 (CMIP5). We use six variations related to the treatment of the atmospheric composition, the calculation of aerosol indirect effects, and ocean model component. Specifically, we test the difference between atmospheric models that have noninteractive composition, where radiatively important aerosols and ozone are prescribed from precomputed decadal averages, and interactive versions where atmospheric chemistry and aerosols are calculated given decadally varying emissions. The impact of the first aerosol indirect effect on clouds is either specified using a simple tuning, or parameterized using a cloud microphysics scheme. We also use two dynamic ocean components: the Russell and HYbrid Coordinate Ocean Model (HYCOM) which differ significantly in their basic formulations and grid. Results are presented for the climatological means over the satellite era (1980–2004) taken from transient simulations starting from the preindustrial (1850) driven by estimates of appropriate forcings over the 20th Century. Differences in base climate and variability related to the choice of ocean model are large, indicating an important structural uncertainty. The impact of interactive atmospheric composition on the climatology is relatively small except in regions such as the lower stratosphere, where ozone plays an important role, and the tropics, where aerosol changes affect the hydrological cycle and cloud cover. While key improvements over previous versions of the model are evident, these are not uniform across all metrics.
Modifying Effect of N‐Acetyltransferase 2 Genotype on the Association Between Systemic Lupus Erythematosus and Consumption of Alcohol and Caffeine‐Rich Beverages
Authors: Kiyohara Chikako , Washio Masakazu , Horiuchi Takahiko , Asami Toyoko , Ide Saburo , Atsumi Tatsuya , Kobashi Gen , Takahashi Hiroki , Tada Yoshifumi ,   the Kyushu Sapporo SLE (KYSS) Study Group
Published: January 2014

ObjectiveN‐acetyltransferase 2 (NAT2) is involved in the metabolism of various environmental substances, both with and without carcinogenic potential. Alcoholic and nonalcoholic caffeine‐rich beverages may be associated with markers of inflammation. Systemic lupus erythematosus (SLE) is a chronic, multifaceted inflammatory disease. We investigated the effects of alcoholic and nonalcoholic caffeine‐rich beverages on risk of SLE and determined whether the effects were modified by NAT2 status.MethodsThe NAT2 polymorphism was genotyped in 152 SLE cases and 427 healthy controls, all women and Japanese. We assessed effect modification by testing an interaction term for the NAT2 polymorphism and consumption of beverages.ResultsConsumption of black tea (odds ratio [OR] 1.88, 95% confidence interval [95% CI] 1.03–3.41) and coffee (OR 1.57, 95% CI 0.95–2.61), but not green tea, was associated with an increased risk of SLE, while alcohol use (OR 0.33, 95% CI 0.20–0.55) was associated with a decreased risk of SLE. There were significant interactions between the NAT2 polymorphism and either alcohol use (Pinteraction = 0.026) or consumption of black tea (Pinteraction = 0.048).ConclusionThe NAT2 polymorphism significantly modified the effects of alcohol use and black tea consumption on SLE, emphasizing the importance of incorporating genetic and metabolic information in studies on management of SLE. Additional studies are warranted to confirm the findings suggested in this study.
Adaptive control for high‐order time‐delay uncertain nonlinear system and application to chemical reactor system
Authors: Lv Li‐Na , Sun Zong‐Yao , Xie Xue‐Jun 
Published: January 2014

SummaryThis paper focuses on global adaptive state‐feedback stabilization for a class of high‐order uncertain nonlinear systems with multiple delays. Restriction on system growth is relaxed. Two dynamic gains are introduced to deal with uncertainty and nonlinear growth rate of the system. Without precise information about time‐delay being needed and only by like Lyapunov function, a new control strategy is presented based on homogeneous domination idea and two necessary transformations. As an application, the developed scheme is utilized to control design of a two‐stage chemical reactor with delayed recycle streams. Copyright © 2014 John Wiley & Sons, Ltd.
A Straightforward Organocatalytic Alkylation of 2‐Arylacetaldehydes: An Approach towards Bisabolanes
Authors: Gualandi Andrea , Canestrari Pietro , Emer Enrico , Cozzi Pier Giorgio 
Published: January 2014

AbstractA highly stereoselective organocatalytic α‐alkylation of 2‐arylacetaldehydes with a commercially available carbenium tetrafluoroborate is described. The stereoselective alkylation was carried out in acetonitrile/water, under air in the presence of a commercially available imidazolidinone (MacMillan’s catalyst). Key intermediates for the synthesis of bisabolanes were obtained through a simple chemistry. In particular a direct, enantioselective and facile synthesis of (R)‐(−)‐curcumene is described.magnified image
Silicon‐Microtube Scaffold Decorated with Anatase TiO2 as a Negative Electrode for a 3D Litium‐Ion Microbattery
Authors: Eustache Etienne , Tilmant Pascal , Morgenroth Laurence , Roussel Pascal , Patriarche Gilles , Troadec David , Rolland Nathalie , Brousse Thierry , Lethien Christophe 
Published: January 2014

An optimized scaffold based on silicon microtubes is designed to increase the surface capacity of 3D lithium‐ion microbatteries. High‐depth, mechanically robust microstructures are fabricated using microelectronic facilities. Conformal deposition of anatase TiO2 is achieved using atomic layer deposition, realizing the targeted improvement for microbatteries; a surface capacity of 0.2 mA h cm–2 at a charge rate of C/10 is obtained in standard liquid electrolyte. This work paves the way for the fabrication of solid‐state 3D Li‐ion microbatteries with an efficient 3D scaffold.