bluuebunny/crossref_metadata_2025_split huggingface dataset:
Indian Prospects for the Tiger Economy of 21st Century
Authors: Kumar Manoj 
Published: September 2015

This paper attempts to unravel the historical place of pride of Indian exports and the present sorry state of affairs. India's performance on several indicators as reported by a multitude of international agencies also presents a grim picture. Our unenviable track record in terms of conviction for reforms, weak Infrastructure and lack of patent protection are some of the areas where India does not present a very good picture. The only areas where there could be any hope are – marketing the Indian educational system abroad, exploiting space, oceans and tourism. Some of the Indian private companies such as Ranbaxy and Sundaram Fasteners are going global, the other Indian companies should take a leaf out of this example. At the same time a few questions need to be fully answered such as: 1. Could there be an emotional backlash against globalisation? 2. Are unilateral sanctions under WTO still possible? 3. The pitfalls of globalisation.
Effect of feline skin specimen preparation on postexcision and postfixation tissue shrinkage
Authors: Risselada Marije , Mathews Kyle G , Griffith Emily 
Published: September 2015

Objectives This study was performed to assess skin–muscle–fascia specimen shrinkage and donor site changes, and to compare three techniques of specimen preparation for their effect on specimen shrinkage postexcision and after formalin fixation in feline cadaveric specimens. Methods Fifteen fresh feline cadavers were used for this study. Gelatin spheres were implanted in paired thoracic subcutaneous pockets and subsequently excised with 30 mm lateral margins and a fascial plane as the deep margin. Skin and fascia were either left unsutured, sutured together using four simple interrupted quadrant sutures (‘four-quadrant-sutured’) or sutured together in a continuous pattern (‘circumferentially sutured’). Specimens were measured for tumor-free margins on the excised and fixed specimens. The donor site defect was assessed for enlargement after specimen excision. Statistical analyses were performed to assess the donor site enlargement, and the influence of preparation technique on margin size, with significance set at P <0.05. Results The closest skin margins on the excised and fixed specimens were significantly smaller than the planned 30 mm margins; however, no significant difference was found between postexcision and postfixation specimens. No significant differences were found between the three techniques ( P = 0.74) with regard to margins either after excision or fixation. The fascial and skin defects of the donor site were significantly larger than the planned excision. Conclusions and relevance Surgically obtained feline skin–muscle–fascia specimens will significantly decrease in size prior to formalin fixation, resulting in falsely decreased measurements from tumor to tissue margins. Affixing the skin to the fascia does not significantly influence this decrease in margin size in feline tissue specimens at this location.
Reliability of classification of ring and little finger carpometacarpal joint fracture subluxations: a comparison between two-dimensional computed tomography and three-dimensional computed tomography classifications
Authors: Kim J. H. , Kwon S.-S. , Moon S. J. , Choe J. S. , Kwak H. I. , Lee S. Y. , Le H. J. , Kim J. Y. 
Published: September 2015

The aims of this study were to develop a classification for ring and little finger carpometacarpal joint fracture subluxations based on three-dimensional computed tomography images and evaluate the inter- and intraobserver reliability of the three-dimensional computed tomography classification. A retrospective review was performed of 30 cases of ring and little finger carpometacarpal joint fracture subluxations from 2005 to 2013. We classified ring and little finger carpometacarpal joint fracture subluxations into three types based on three-dimensional computed tomography images. An orthopaedic surgeon with 2 years of experience, a consultant hand surgeon with 8 years of experience, and a consultant radiologist with 9 years of experience, who were completely blind to the treatment algorithm, evaluated 30 cases twice at a 2-week interval using our new classification based on three-dimensional computed tomography images and the other classification based on two-dimensional computed tomography images. Our three-dimensional computed tomography classification showed almost perfect interobserver and intraobserver reliability and resulted in a better level of agreement than two-dimensional computed tomography classification. Level of Evidence: IV
Structural Changes by Spectral Domain Optical Coherence Tomography in Patients With Type 1 Diabetes Mellitus
Authors: Mendez Nicole , Kommana Sumana S. , Szirth Bernard , Khouri Albert S. 
Published: September 2015

Background: With a possible increase in the prevalence of type 1 diabetes mellitus (DM1), the pediatric patient population is expected to be at risk for other health care complications. Current imaging modalities, such as the spectral domain optical coherence tomography (SD-OCT), that allow micron resolution imaging of the retina have become a standard of care for showing morphological changes seen in the retina in adults with diabetes. Such pathologies can be associated with known risk factors such as poor glycemic control (HbA1C) and body mass index (BMI). Methods: A comprehensive screening was performed in subjects with DM1 including nonmydriatic fundus imaging (Canon, CR2 Plus-AF with EOS-60D, Tokyo, Japan) and SD-OCT imaging (Optovue, iVue, Fremont, CA). SD-OCT scans were acquired showing macular thickness (MT) and thickness of the parafoveal regions and the perifoveal regions. Associations of macular, paramacular, and perimacular thickness were analyzed as a function of HbA1C and BMI by simple linear regressions. Results: SD-OCT changes were analyzed in eyes of subjects with DM1 and normal fundus appearance by color imaging. Linear regression analysis of thickness of macula right eye (RT), paramacula RT, paramacula left eye (LT), perimacula LT with BMI were statistically significant ( P < .05). HbA1C >7.5% was also found statistically significant in the macula RT, paramacula RT, paramacula LT, perimacula RT, and perimacula LT. A general trend of thickening of the macula, paramacula, and perimacula was observed with increasing HbA1C (>7.5%) and increasing BMI; however, no statistical significance was found. Conclusions: SD-OCT with retinal imaging was feasible in young individuals with DM1 and revealed ultrastructural macular and perimacular changes prior to manifest clinical disease.
The relationship between upper airway collapse and the severity of obstructive sleep apnea syndrome: A chart review
Authors: Schwartz Russell N. , Payne Richard J. , Forest Véronique-Isabelle , Hier Michael P. , Fanous Amanda , Vallée-Gravel Camille 
Published: September 2015

Background We sought to determine the ability of the endoscopic Mueller maneuver (MM) to predict the severity of OSAS based on upper airway (UA) collapse. Methods This chart review retrospectively analyzed the results of endoscopic Mueller maneuvers examining the UA on 506 patients suspected of having OSAS. There were 3 areas of UA collapse that were evaluated: velopharynx (VP), base of tongue (BOT), and lateral pharyngeal walls (LPW). A sleep study was done after the examination to assess the severity of OSAS based on the apnea-hypopnea index (AHI). Results A total of 506 patients met criteria for OSAS, with 194 mild cases (5 ≤ AHI < 15), 163 moderate cases (15 ≤ AHI < 30) and 149 severe cases (30 ≤ AHI). At the VP, 30 patients had minimal collapse (mean AHI = 17); 41 patients had moderate VP collapse (mean AHI = 25); 392 patients had severe VP collapse (mean AHI = 27). At the BOT, 144 patients had minimal collapse (mean AHI = 19); 187 patients had moderate BOT collapse (mean AHI = 24); 175 patients had severe BOT collapse (mean AHI = 33). At the LPW, 158 patients had minimal collapse (mean AHI = 20); 109 patients had moderate LPW collapse (mean AHI = 25); 120 patients had severe LPW collapse (mean AHI =33). The correlations found between VP collapse, BOT collapse, and LPW collapse and OSAS severity were: r = 0.069 (95 % CI; −0.022, 0.16), r = 0.26 (95 % CI; 0.18, 0.34) and r = 0.22 (95 % CI; 0.12, 0.31), respectively. Conclusions In this study, the degree of collapse of the UA at all levels, especially at the BOT and LPW levels, correlate significantly with the severity of OSAS. The Mueller maneuver helped identify patients with severe sleep apnea based on UA collapse. The MM cannot be used to diagnose OSAS, but can be a valuable tool to help the physician estimate the severity of sleep apnea and the urgency to obtain a sleep study.
Time to Revisit the Problem of CIN? The Low Incidence of Acute Kidney Injury with and without Contrast in Hospitalized Patients: An Observational Cohort Study
Authors: Hemmett Juliya , Er Lee , Chiu Helen H. L. , Cheung Christopher , Djurdjev Ognjenka , Levin Adeera 
Published: September 2015

Background: Acute kidney injury (AKI) following imaging procedures with contrast medium in hospitalized patients is commonly attributed to contrast-induced nephropathy (CIN). This study sought to establish a benchmark of the incidence of AKI in hospitalized patients who underwent computed tomography (CT) scans, with and without intravenous contrast administration. Methods: This was a multi-center observational cohort study. Hospitalized patients in four hospitals with CT scans during two time periods in 2012 and 2013 were included. AKI post-scan was defined as a change in serum creatinine (sCr) in absolute terms of ≥26.5 μmol/L (≥0.3 mg/dl), occurring within 7 days of the CT scan. AKI incidence was examined by study phases and CT-scan types using logistic regression models. Multinomial logistic regression was used to examine the proportions of sCr availability between two study phases. Results: Three hundred and twenty-five patients in Period 1 and 518 patients in Period 2 were included in the study. The incidence of AKI in Period 1 was similar in those who received contrast and in those who did not (11.6 % [95 % C.I.: 6.5, 18.7] vs. 10.1 % [95 % C.I.: 5.1, 17.3]; p = 0.38). The incidence of AKI remained not significantly different between the two periods in those who received contrast (11.6 % [95 % C.I.: 6.5, 18.7] vs. 10.7 % [95 % C.I.: 6.8, 15.8]; p = 0.89) and those who did not (10.1 % [95 % C.I.: 5.1, 17.3] vs. 9.1 % [95 % C.I.: 5.2, 14.6]; p = 0.54). Among those who received contrast, there was a significant increase in the availability of both pre- and post- CT scan sCr in Period 2 compared to Period 1 (73.6 % [95 % C.I.: 67.7, 80.6] vs. 79.8 % [95 % C.I.: 75.2, 84.7]; p = 0.006). Limitations: Our study was not targeted to specifically assess the impact of a prevention protocol on the incidence of AKI and was limited to settings within one health authority in the province. Conclusion: In hospitalized patients, the incidence of AKI is low, not different between those who did and did not receive contrast, and was not impacted by improvement in the monitoring of sCr in at risk patients. A better understanding of the determinants of AKI post-contrast scan is required to improve strategies to reduce the incidence of AKI.
Improved-high-quality draft genome sequence of Rhodococcus sp. JG-3, a eurypsychrophilic Actinobacteria from Antarctic Dry Valley permafrost
Authors: Goordial Jacqueline , Raymond-Bouchard Isabelle , Ronholm Jennifer , Shapiro Nicole , Woyke Tanja , Whyte Lyle , Bakermans Corien 
Published: September 2015

AbstractThe actinobacteriumRhodococcus sp. JG-3 is an aerobic, eurypsychrophilic, soil bacterium isolated from permafrost in the hyper arid Upper Dry Valleys of Antarctica. It is yellow pigmented, gram positive, moderately halotolerant and capable of growth from 30 °C down to at least −5 °C. The 5.28 Mb high-quality-draft genome is arranged into 6 scaffolds, containing 9 contigs and 4998 protein coding genes, with 64 % GC content. Increasing the availability of genome sequences from cold-adapted species is crucial to gaining a better understanding of the molecular traits of cold adaptation in microbes.
Generating a high-resolution global magnetic model for oil and mineral exploration
Authors: Fairhead J. D. , Green C. M. 
Published: September 2015

Summary This is the final contribution to the trilogy of articles on global potential-field data compilations. Getech's continental and national magnetic data compilations commenced in 1989 and were designed specifically for use in petroleum and mineral exploration. These studies complemented the continental-scale gravity-compilation studies that were the subject of the TLE “Meter Reader” contributions in March and May of this year. The success of these projects resulted from strategic partnerships, especially with Paterson, Grant and Watson Ltd. (PGW), and links to a wide range of national organizations. Early compilations covering the whole of Africa, South America, and China were followed by large-scale, small-scale, and national compilations and continue to this day with compilations of U. S. surveys. The projects spawned a range of technical developments, including approaches to remove survey-line noise, the integration of survey grids and disparate ship-track data, and the preservation of the longest-wavelength anomalies associated with the crustal magnetic field. The resulting global gravity and magnetic grids now form an invaluable resource for resource exploration.
Bumblebee flight performance in cluttered environments: effects of obstacle orientation, body size and acceleration
Authors: Crall James D. , Ravi Sridhar , Mountcastle Andrew M. , Combes Stacey A. 
Published: September 2015

ABSTRACTLocomotion through structurally complex environments is fundamental to the life history of most flying animals, and the costs associated with movement through clutter have important consequences for the ecology and evolution of volant taxa. However, few studies have directly investigated how flying animals navigate through cluttered environments, or examined which aspects of flight performance are most critical for this challenging task. Here, we examined how body size, acceleration and obstacle orientation affect the flight of bumblebees in an artificial, cluttered environment. Non-steady flight performance is often predicted to decrease with body size, as a result of a presumed reduction in acceleration capacity, but few empirical tests of this hypothesis have been performed in flying animals. We found that increased body size is associated with impaired flight performance (specifically transit time) in cluttered environments, but not with decreased peak accelerations. In addition, previous studies have shown that flying insects can produce higher accelerations along the lateral body axis, suggesting that if maneuvering is constrained by acceleration capacity, insects should perform better when maneuvering around objects laterally rather than vertically. Our data show that bumblebees do generate higher accelerations in the lateral direction, but we found no difference in their ability to pass through obstacle courses requiring lateral versus vertical maneuvering. In sum, our results suggest that acceleration capacity is not a primary determinant of flight performance in clutter, as is often assumed. Rather than being driven by the scaling of acceleration, we show that the reduced flight performance of larger bees in cluttered environments is driven by the allometry of both path sinuosity and mean flight speed. Specifically, differences in collision-avoidance behavior underlie much of the variation in flight performance across body size, with larger bees negotiating obstacles more cautiously. Thus, our results show that cluttered environments challenge the flight capacity of insects, but in surprising ways that emphasize the importance of behavioral and ecological context for understanding flight performance in complex environments.
Negative energy balance in a male songbird, the Abert's towhee, constrains the testicular endocrine response to luteinizing hormone stimulation
Authors: Davies Scott , Gao Sisi , Valle Shelley , Bittner Stephanie , Hutton Pierce , Meddle Simone L. , Deviche Pierre 
Published: September 2015

ABSTRACTEnergy deficiency can suppress reproductive function in vertebrates. As the orchestrator of reproductive function, endocrine activity of the hypothalamo-pituitary–gonadal (HPG) axis is potentially an important mechanism mediating such effects. Previous experiments in wild-caught birds found inconsistent relationships between energy deficiency and seasonal reproductive function, but these experiments focused on baseline HPG axis activity and none have investigated the responsiveness of this axis to endocrine stimulation. Here, we present data from an experiment in Abert's towhees, Melozone aberti, using gonadotropin-releasing hormone (GnRH) and luteinizing hormone (LH) challenges to investigate whether energy deficiency modulates the plasma testosterone responsiveness of the HPG axis. Wild-caught birds were either ad libitum fed or energetically constrained via chronic food restriction during photoinduced reproductive development. Energy deficiency did not significantly affect the development of reproductive morphology, the baseline endocrine activity of the HPG axis, or the plasma testosterone response to GnRH challenge. Energy deficiency did, however, decrease the plasma testosterone responsiveness to LH challenge. Collectively, these observations suggest that energy deficiency has direct gonadal effects consisting of a decreased responsiveness to LH stimulation. Our study, therefore, reveals a mechanism by which energy deficiency modulates reproductive function in wild birds in the absence of detectable effects on baseline HPG axis activity.
Interaction of osmoregulatory and acid–base compensation in white sturgeon (Acipenser transmontanus) during exposure to aquatic hypercarbia and elevated salinity
Authors: Shaughnessy Ciaran A. , Baker Dan W. , Brauner Colin J. , Morgan John D. , Bystriansky Jason S. 
Published: September 2015

ABSTRACTMigratory fishes encounter a variety of environmental conditions, including changes in salinity, temperature and dissolved gases, and it is important to understand how these fishes are able to acclimate to multiple environmental stressors. The gill is the primary site of both acid–base balance and ion regulation in fishes. Many ion transport mechanisms involved with acid–base compensation are also required for the regulation of plasma Na+ and Cl+, the predominant extracellular ions, potentially resulting in a strong interaction between ionoregulation and acid–base regulation. The present study examined the physiological interaction of elevated dissolved CO2 (an acid–base disturbance) on osmoregulation during seawater acclimation (an ionoregulatory disturbance) in juvenile white sturgeon (Acipenser transmontanus). Blood pH (pHe), plasma [HCO3−], [Na+], [Cl−] and osmolality, white muscle water content, and gill Na+/K+-ATPase (NKA) and Na+/K+/2Cl− co-transporter (NKCC) abundance were examined over a 10 day seawater (SW) acclimation period under normocarbia (NCSW) or during prior and continued exposure to hypercarbia (HCSW), and compared with a normocarbic freshwater (NCFW) control. Hypercarbia induced a severe extracellular acidosis (from pH 7.65 to pH 7.2) in HCSW sturgeon, and these fish had a 2-fold greater rise in plasma osmolarity over NCSW by day 2 of SW exposure. Interestingly, pHe recovery in HCSW was associated more prominently with an elevation in plasma Na+ prior to osmotic recovery and more prominently with a reduction in plasma Cl− following osmotic recovery, indicating a biphasic response as the requirements of osmoregulation transitioned from ion-uptake to ion-excretion throughout SW acclimation. These results imply a prioritization of osmoregulatory recovery over acid–base recovery in this period of combined exposure to acid–base and ionoregulatory disturbances.
Using Duration and Volatility Rates to Estimate Risk Indexes of Investment Projects
Authors: Титова  , Titova N. , Титов  , Titov S. , Титаренко  , Titarenko R. 
Published: September 2015

The article proposes to applyduration and volatility rates, traditionally used to analyse financial risks, to estimate
risk indexes of investment projects, and defines these rates’ main advantages.
Home Bias in Online Investments: An Empirical Study of an Online Crowdfunding Market
Authors: Lin Mingfeng , Viswanathan Siva 
Published: September 2015

An extensive literature in economics and finance has documented home bias, the tendency that transactions are more likely to occur between parties in the same geographical area rather than outside. Using data from a large online crowdfunding marketplace and employing a quasi-experimental design, we find evidence that home bias still exists in this virtual marketplace for financial products. Furthermore, through a series of empirical tests, we show that rationality-based explanations cannot fully explain such behavior and that behavioral reasons at least partially drive this remarkable phenomenon. As crowdfunding becomes an alternative and increasingly appealing channel for financing, a better understanding of home bias in this new context provides important managerial, practical, and policy implications. This paper was accepted by Lee Fleming, entrepreneurship and innovation.
The acceptability of case-finding questions to identify perinatal depression
Authors: Mann Rachel , Adamson Joy , Gilbody Simon 
Published: September 2015

Background: Guidance from the National Institute for Health and Care Excellence advocates the use of two case-finding questions about depressed mood and loss of interest in activities to identify perinatal depression. However, there are no studies of their acceptability when administered in the antenatal and postnatal period. Methods: The study was an intra-mixed methods cohort study set in an antenatal clinic in an inner-city hospital in the North of England. Pregnant women attending a routine antenatal appointment at approximately 26 weeks' gestation completed a self-report survey at a routine hospital antenatal appointment and a postal survey between 5 and 13 weeks postnatal. Survey responses and free-text commentaries of women's views were analysed using descriptive statistics and qualitative content analysis. Results: Ninety-three percent of participants felt it was desirable to ask about perinatal mental wellbeing, and 97% felt comfortable answering the questions. Free-text comments revealed depressed and non-depressed women found the questions easy, simple and straightforward to answer. Conclusions: Case-finding questions to identify perinatal depression were generally acceptable to depressed and non-depressed pregnant and newly delivered mothers. Health professionals should consider the acceptability and appropriateness of this strategy in order to facilitate identification of perinatal mental health issues in routine maternity care practice.