bluuebunny/crossref_metadata_2025_split huggingface dataset:
Patient satisfaction with psychiatric outpatient care in a university hospital setting
Authors: Lally John , Byrne Fintan , McGuire Eimear , McDonald Colm 
Published: October 2013

ObjectivesTo measure patient satisfaction with psychiatric outpatient care in a university hospital setting. We wished to ascertain whether there was an association between increased patient satisfaction and background factors such as demographic details, diagnosis and patient preference for outpatient treatment in a hospital or a community setting.MethodsWe conducted a cross-sectional survey of individuals’ satisfaction levels with their outpatient treatment. Outpatients were invited to complete the Client Satisfaction Questionnaire-8 (CSQ-8), a well validated self-report instrument, along with some additional questions on their attitudes to the service.ResultsOne hundred and sixty-two respondents had a mean total CSQ-8 score of 26.7 (s.d. = 4.6) indicating a moderate to high level of satisfaction with outpatient care. Ninety percent of patients were satisfied with their psychiatric outpatient care. There were no significant sociodemographic or clinical associations with satisfaction levels identified. Sixty one percent of patients were in favour of retaining outpatient care in the university hospital.ConclusionsThis study demonstrates high satisfaction levels with psychiatric outpatient care in a university hospital setting. The majority of patients expressed a preference for maintaining outpatient care in the general hospital setting, rather than transferring to a stand-alone mental health facility in a suburban setting.
A short historical review of SCNP with special reference to the UKU
Authors: Bech Per , Ban Thomas A. 
Published: October 2013

ObjectiveTo give a review of the history of SCNP since the first meeting in 1960 with specific focus on UKU.MethodsConsulting the appropriate minutes from the meetings.ResultsOne of the major goals of the SCNP was the standardization of clinical trials with psychotropic drugs. In 1969, the SCNP established a Committee for Clinical Investigations (UKU) with the representation of clinical investigators and the drug industry; moreover, during the 1970s and ’80s, the UKU initiated clinical trialsand contributed to the methodology of clinical investigations with psychotropic drugs. With the decrease in governmental funding and increasing influence of the US Food and Drug Administration on themethodology of clinical investigations around the world in the 1990s, the UKU was dissolved. The changes had a detrimental effect on the developments on the methodology of clinical investigations, and the lack of clinical feedback led to an impasse in psychotropic drug development with some pharmaceutical companies abandoning research in the central nervous system area.ConclusionIt is suggested that a revival of UKU to provide a platform for dialogue among government, industry, and academia could help break the impasse.
Acoustic, perceptual and aerodynamic voice evaluation in an obese population
Authors: Celebi S , Yelken K , Develioglu O N , Topak M , Celik O , Ipek H D , Kulekci M 
Published: October 2013

AbstractObjective:To investigate perceptual, acoustic and aerodynamic voice parameters in obese individuals.Methods:Twenty obese and 20 normal-weight volunteers underwent voice evaluation by laryngoscopy, acoustic analysis, aerodynamic measurement and perceptual analysis (using the grade-roughness-breathiness-asthenia-strain (‘GRBAS') scale and the Voice Handicap Index 10 scale). Data from both subject groups were compared.Results:No difference was found in acoustic analysis parameters between the two groups (p > 0.05). Maximum phonation time in the obese group (mean ± standard deviation, 19.6 ± 4.9 seconds) was significantly shorter than in controls (26.4 ± 4.1 seconds) (p < 0.001), although the s/z ratio was very similar between the two groups. In the obese and control groups, the mean ± standard deviation grade-roughness-breathiness-asthenia-strain scores were 1 ± 1.3 and 0.2 ± 0.6 (p = 0.002) and the mean ± standard deviation Voice Handicap Index 10 scores were 0.5 ± 1.2 and 1.2 ± 1.7 (p = 0.27), respectively.Conclusion:Obese individuals had poorer vocal quality as judged by the grade-roughness-breathiness-asthenia-strain scale, and reduced maximum phonation time. However, there was no change in voice quality as assessed by acoustic analysis and Vocal Handicap Index 10 score, compared with controls.
Role of neck dissection for metastatic nonseminomatous testicular carcinoma: case report and literature review
Authors: O'Connor A , Dias A , Timon C 
Published: October 2013

AbstractObjectives:To review the incidence, treatment and prognosis of testicular carcinoma metastatic to the neck, and to propose a selective neck dissection be performed for residual disease post-chemotherapy.Case report:A 17-year-old young man with metastatic testicular carcinoma presented with a left neck mass. A palpable neck mass is the initial sign in approximately 5 per cent of cases of metastatic testicular teratoma. Approximately 30 per cent of patients with advanced-stage testicular cancer have extra-retroperitoneal disease post-chemotherapy, which requires resection. The presented patient underwent a left selective neck dissection, thymectomy, median sternotomy, left thoracotomy and mediastinal lymph node dissection. Eighteen months later, a computed tomography scan of the thorax showed no evidence of disease recurrence in the neck or mediastinum.Conclusion:While surgical management of testicular cancer retroperitoneal metastases is well described, there is limited literature on the management of cervical lymph node metastases. In the presented case of metastatic testicular carcinoma with cervical lymph node metastases, a selective neck dissection was successfully performed for a post-chemotherapy mass.
Post-aural ache: an unusual presentation of a metastatic temporal bone lesion from a primary adenocarcinoma of the lung
Authors: Thirunavukarasu V , Carter T , Dezso A , Holland C 
Published: October 2013

AbstractObjective:We report a rare case of temporal bone metastasis from a lung primary, presenting only as post-aural tenderness.Case report:A 57-year-old man presented to our out-patient department with left post-aural pain of four months' duration. Clinical examination revealed tenderness in the left post-aural region; the ear, nose and throat examination was otherwise unremarkable. Computed tomography and contrast-enhanced magnetic resonance imaging showed erosion of the left petrous temporal bone. Incisional biopsy was carried out. Histopathological and immunohistochemical analysis showed infiltrative metastatic adenocarcinoma of the lung. Further imaging with positron emission tomography confirmed increased uptake from the right lower lobe of the lung, suggesting the site of the primary lesion. The patient was treated with chemo-radiotherapy.Conclusion:Post-aural pain is a non-specific symptom, and, with normal clinical and audiometric test results, rare lesions such as the one presented could be easily missed. A thorough clinical examination must be performed to identify genuine signs, and appropriate imaging undertaken to exclude rare causes, such as this metastatic lesion of the temporal bone.
Respect for the Moral Law: the Emotional Side of Reason
Authors: DeWitt Janelle 
Published: October 2013

AbstractRespect, as Kant describes it, has a duality of nature that seems to embody a contradiction – i.e., it is both a moral motive and a feeling, where these are thought to be mutually exclusive. Most solutions involve eliminating one of the two natures, but unfortunately, this also destroys what is unique about respect. So instead, I question the non-cognitive theory of emotion giving rise to the contradiction. In its place, I develop the cognitive theory implicit in Kant's work, one in which emotions take the form of evaluative judgments that determine the will. I then show that, as a purely rational emotion, respect is perfectly suited to be a moral motive.
Human Agency, Reasons, and Inter-subjective Understanding
Authors: Hasselberger William 
Published: October 2013

AbstractIn this essay I ague that the mainstream ‘Standard Story’ of action – according to which actions are bodily motions with the right internal mental states as their causal triggers (e.g., ‘belief-desire-pairs’, ‘intentions’) – gives rise to a deeply problematic conception of inter-subjective action-understanding. For the Standard Story, since motivating reasons are internal mental states and bodily motions are not intrinsically intentional, an observer mustascribeinternal states to others to make rational sense of their outwardly observable bodily motions. I argue this is both phenomenologically distorted and requires, on pain of infinite regress, a deeper, non-inferential, practical-perceptual form of understanding: ‘knowledge-how’, in a broadly Rylean sense. Recognizing the irreducible role of practical-perceptual knowledge-how in inter-subjective understanding, I argue, undermines core assumptions of the Standard Story concerning what an agent can directly perceive in interacting with others, and how our everyday practices of explaining actions with reasons function – and this opens the space for a radically opposed alternative view of inter-subjective action understanding.
Genotyping of Giardia isolates in Scotland: a descriptive epidemiological study
Authors: ALEXANDER C. , JONES B. , INVERARITY D. , POLLOCK K. G. J. 
Published: October 2013

SUMMARYGiardiasis, caused by the intestinal protozoan parasite Giardia intestinalis (synonyms: G. lamblia, G. duodenalis), is one of the most frequent parasites to infect the Scottish population. Transmission of the infective cysts in faecal matter is commonly via food and/or water. Giardia is subdivided into assemblages, where clinical and epidemiological differences have been described between assemblages A and B. This snapshot descriptive epidemiological study examines 30 positive cases of Giardia of which 72% (n = 21) were shown to be assemblage A, 14% (n = 4) assemblage B and 10% (n = 3) mixed assemblages (A and B). There was a 2:3 female:male ratio of affected individuals with foreign travel recorded in 22 of these cases. The commonest symptom was diarrhoea which was reported in 80% of cases followed by tiredness. Five cases required hospitalization emphasizing the importance of gaining a greater understanding of how Giardia assemblages influence clinical outcomes to assist in formulating guidelines to manage potential Giardia outbreaks.
A frequency questionnaire to estimate free-living physical activity among Tunisian preadolescent and adolescent children
Authors: Ben Gharbia Houda , Gartner Agnès , Traissac Pierre , Delpeuch Francis , Maire Bernard , El Ati Jalila 
Published: October 2013

AbstractObjectiveTo develop a child- and adolescent-appropriate physical activity frequency questionnaire (PAFQ) in Tunisia, North Africa.DesignA PAFQ was developed from a physical activity (PA) inventory that comprised major activity components (at home, preparing meals, school time, transport, non-sport leisure, sports, prayer and sleeping time). Then, type and duration of each activity undertaken during the past week were estimated. Total energy expenditure (TEE) estimated by the PAFQ was compared with data derived from two criterion methods: heart-rate monitoring (HRM) and a 24 h PA recall (24h-R), both collected during a 3 d period including one weekday and two weekend days.SettingTwo elementary schools and two high schools of the most developed and urbanized area, Greater Tunis.SubjectsOne hundred and forty-two volunteer children and adolescents aged 10–19 years.ResultsThe PAFQ strongly was correlated with both HRM (r= 0·70; 95 % CI 0·62, 0·76) and 24h-R (r= 0·81; 95 % CI 0·77, 0·84). It featured acceptable agreement with both criterion measures, slightly underestimating TEE compared with 24h-R (−2·8 %, mean of individual differences −272·7 kJ/d; 95 % CI −490·6, −57·4 kJ/d) and moderately overestimating it compared with HRM (+11·3 %, mean of individual differences +1106·2 kJ/d; 95 % CI 845·8, 1366·6 kJ/d). Reliability ranged from moderate to good (weighted kappa coefficients from 0·47 to 0·78 and intra-class correlation coefficients between 0·79 and 0·86 for energy expenditure by PA categories), indicating strong agreement between the two assessments.ConclusionsThis PAFQ could be useful in the description and surveillance of PA patterns or for the evaluation of population-based interventions directed at promoting PA in Tunisian children and adolescents.
Ionic Liquids as Floatation Media for Cryo-Ultramicrotomy of Soft Polymeric Materials
Authors: Kim Paul , David Emeric , Raboin Louis , Ribbe Alexander E. , Russell Thomas P. , Hoagland David A. 
Published: October 2013

AbstractIonic liquids (ILs) and their mixtures with low molecular solvents present ideal properties for use as flotation liquids in cryo-ultramicrotomy. With control of Tg and η by co-solvent addition, flat, ultra-thin sections are reliably floated onto transmission electron microscopy grids even at temperatures as low as −100°C. Even more, the liquids and their mixtures are stable in the microtome trough for several hours because of low vapor pressure and low solidification temperature. Compared to established flotation media for soft polymer systems, the time and skill needed for cryo-ultramicrotomy are significantly reduced. Although just a handful of ILs are discussed and a good general choice identified, if different liquid characteristics are needed for a particular sample, thousands of additional ILs will perform similarly, giving this new approach enormous flexibility.
Advocacy in Pain Management: The Role of the Anaesthetic Nurse Specialist
Authors: McLean G. , Martin D. , Cousley A. , Hoy L. 
Published: October 2013

AbstractPeri-operative nursing practice is constantly changing and demanding specialist knowledge, skills and expertise to embrace these changes. All patients in need of anaesthesia are entitled to the same high quality peri-operative care and therefore those assisting the anaesthetist must be competent and effective practitioners. With this in mind the authors shall give a reflective account highlighting the role of Anaesthetic Nurse Specialist (ANS) in promoting leadership within the peri-operative environment and how it can be nurtured and facilitated to achieve professional autonomy and promote patient advocacy.
HnRNP L and hnRNP LL antagonistically modulate PTB-mediated splicing suppression of CHRNA1 pre-mRNA
Authors: Rahman Mohammad Alinoor , Masuda Akio , Ohe Kenji , Ito Mikako , Hutchinson David O. , Mayeda Akila , Engel Andrew G. , Ohno Kinji 
Published: October 2013

AbstractCHRNA1 gene, encoding the muscle nicotinic acetylcholine receptor alpha subunit, harbors an inframe exon P3A. Inclusion of exon P3A disables assembly of the acetylcholine receptor subunits. A single nucleotide mutation in exon P3A identified in congenital myasthenic syndrome causes exclusive inclusion of exon P3A. The mutation gains a de novo binding affinity for a splicing enhancing RNA-binding protein, hnRNP LL and displaces binding of a splicing suppressing RNA-binding protein, hnRNP L. The hnRNP L binds to another splicing repressor PTB through the proline-rich region and promotes PTB binding to the polypyrimidine tract upstream of exon P3A, whereas hnRNP LL lacking the proline-rich region cannot bind to PTB. Interaction of hnRNP L with PTB inhibits association of U2AF65 and U1 snRNP with the upstream and downstream of P3A, respectively, which causes a defect in exon P3A definition. HnRNP L and hnRNP LL thus antagonistically modulate PTB-mediated splicing suppression of exon P3A.
Ecological and evolutionary effects of harvesting: lessons from the candy-fish experiment
Authors: Diaz Pauli Beatriz , Heino Mikko 
Published: October 2013

Abstract
Diaz Pauli, B., and Heino, M. 2013. Ecological and evolutionary effects of harvesting: lessons from the candy-fish experiment. – ICES Journal of Marine Science, 70: . Understanding the challenges of sustainable fisheries management is not easy for non-specialists, and even many specialists fail to appreciate the potential evolutionary consequences of harvest. We propose candy-fish experiments as a savoury approach to teaching and disseminating the key principles of applied ecology and evolution to students, practitioners and the general public. We performed a simple experiment where the resource was represented by fish-shaped candy of distinct colours and flavours (strawberry and liquorice). Typically, harvesting was neither ecologically sustainable (55% of the populations were extinct by the end of the experiment) nor evolutionarily sustainable (most surviving populations had liquorice fish only). This harvest-induced evolution went apparently unnoticed. Somewhat encouragingly, the harvest was most likely ecologically sustainable when a person spontaneously took the role of a stock manager.
Assessment of Paraspinal Muscle Cross-sectional Area After Lumbar Decompression
Authors: Bresnahan Lacey E. , Smith Justin S. , Ogden Alfred T. , Quinn Steven , Cybulski George R. , Simonian Narina , Natarajan Raghu N. , Fessler Richard D. , Fessler Richard G. 
Published: October 2013

Study Design:
A retrospective, blinded analysis of imaging studies.

Summary of Background Data:
To evaluate changes in paraspinal muscle cross-sectional area (CSA) after surgical treatment for lumbar stenosis and to compare these changes between minimally invasive and standard open approaches. The open approach to lumbar stenosis is effective, but it involves retraction and resection of muscle from the spinous process, which can result in ischemia and denervation of paraspinal musculature and may lead to muscle atrophy and pain.

Objective:
It is hypothesized that the microendoscopic decompression of stenosis (MEDS) technique will better preserve the paraspinal muscles compared with the open procedure.

Materials and Methods:
A total of 18 patients underwent a 1-level posterior decompression for lumbar stenosis, (9 open, 9 MEDS). Lumbar magnetic resonance imaging was obtained before surgery and after surgery (open approach average 16.3 mo; MEDS average 16.6 mo). CSA of paraspinal muscles were averaged over the distance of the surgical site.

Results:
The mean age of patients treated with the open and MEDS approaches were 55.2 and 66.4 years, respectively (P=0.07). Paraspinal muscle CSA decreased by an average of 5.4% (SD=10.6%; range, −24.5% to +7.7%) in patients treated with the open approach and increased by an average of 9.9% (SD=14.4%; range, −9.8% to +33.1%) in patients treated with MEDS (P=0.02). For the open approach, changes in CSA did not differ significantly between the left and right sides for erector spinae (P=0.35) or multifidus muscles (P=0.90). After the MEDS approach there were no significant differences between the dilated and contralateral sides with regard to change in CSA for erector spinae (P=0.85) or multifidus muscles (P=0.95).

Conclusions:
Compared with the open approach for lumbar stenosis, MEDS had significantly less negative impact on the paraspinal muscle CSA. Previous reports have documented negative effects of paraspinal muscle injury, including weakness, disability, and pain. Collectively, these data suggest that the MEDS approach for lumbar decompression is less destructive to the paraspinous muscles than the open approach and may facilitate better clinical outcomes.
Toilet Refusal Syndrome in Preschool Children
Authors: Niemczyk Justine , Equit Monika , El Khatib Diana , von Gontard Alexander 
Published: October 2013

ABSTRACTObjectives:Toilet refusal syndrome (TRS) is a common, benign disorder in toddlers defined by the use of diapers and refusal of toilet for defaecation, but has not been described systematically in preschool children yet. The aim of the study was to analyse and identify possible subgroups of TRS.Methods:Retrospective analysis of all of the consecutive children with TRS presented as outpatients in a clinic for elimination disorders. Patients had received a detailed paediatric and child psychiatric assessment, including the Child Behavior Checklist questionnaire. Three typical case vignettes are presented of TRS with constipation, oppositional defiant disorder, and sibling rivalry.Results:Twenty‐five children (10 boys) with a mean age of 5.2 (3.4–7.3) years were included—representing 2.5% of all of the children (n = 1001) presented. They had high rates of constipation (60%) and elimination disorders (24%–44%). Child psychiatric International Classification of Diseases‐10th Edition disorders were common (40%) and heterogeneous, with significantly more boys affected, but no differences between children with and without constipation.Conclusions:This study shows that TRS occurs also in older preschool (and even school) children. At this later age, it is associated with constipation and behavioural disorders. The case vignettes show differences in therapy and may represent different subgroups of TRS. TRS is associated with constipation, elimination disorders, and psychiatric disorders. Owing to this variety of comorbid disorders, different therapeutic approaches are needed. A general screening for behavioural symptoms is recommended.
Implementing mixed methods research in supply chain management
Authors: Golicic Susan L. , Davis Donna F. 
Published: October 2013

PurposeThe purpose of this paper is to describe how to implement mixed methods research in supply chain management.Design/methodology/approachA review of past journal analyses on research methods used in supply chain management‐related disciplines is conducted to demonstrate the low incidence of mixed methods research in supply chain management. Drawing from literature on multiple and mixed methods research, the paper provides guidelines for designing and reporting such studies.FindingsKnowledge development in logistics and supply chain management relies primarily on single‐method quantitative research designs, while mixed methods approaches are rarely used. Thus, there is a significant opportunity to advance the discipline through the rigorous application of mixed methods research.Research limitations/implicationsSupply chain management phenomena are complex and dynamic. Thus, the application of mixed methods research would serve the advancement of the discipline as these approaches provide richer understanding and more robust explanations of such phenomena.Practical implicationsIf supply chain research is to keep up with the dynamic business environment, research methods must be applied with the capability to fully explain supply chain phenomena. The application of a single‐method research approach is not always adequate for this task.Originality/valueThis paper is the first to draw on research from various disciplines to investigate the use of mixed methods in logistics and supply chain management research. It examines its prevalence in the discipline, provides examples of its application from the supply chain management literature, prescribes how to implement mixed methods research, and describes the benefits and limitations of such designs.