bluuebunny/crossref_metadata_2025_split huggingface dataset:
Telehealth Cognitive Behavior Therapy for Co‐Occurring Insomnia and Depression Symptoms in Older Adults
Authors: Lichstein Kenneth L. , Scogin Forrest , Thomas S. Justin , DiNapoli Elizabeth A. , Dillon Haley R. , McFadden Anna 
Published: August 2013

ObjectiveTelehealth has proven effective with a wide range of disorders, but there is a paucity of data on the use of telehealth using cognitive‐behavior therapy (CBT) with late‐life insomnia and depression. This pilot study was designed to examine the feasibility and effectiveness of using telehealth to treat older adults with comorbid insomnia and depression living in rural Alabama.MethodFive patients received 10 sessions of CBT for insomnia and depression. Patients were engaged in treatment via Skype from their primary care physician's office. Assessments were conducted at baseline, posttreatment, and 2‐month follow‐up.ResultsPatients exhibited clinically significant improvement in both insomnia (sleep diaries and Insomnia Severity Index) and depression (Hamilton Rating Scale for Depression) at posttreatment, and these gains were well maintained at 2‐month follow‐up.ConclusionsThese preliminary data suggest that telehealth may be an effective means of providing treatment to older adults, including underserved populations.
Effects of polymorphisms of the SLCO2B1 transporter gene on the pharmacokinetics of montelukast in humans
Authors: Kim Kyoung‐Ah , Lee Hye‐Mi , Joo Hyun‐Jin , Park In‐Bae , Park Ji‐Young 
Published: August 2013

AbstractMontelukast, a leukotriene receptor antagonist, is a substrate of organic anion transporting OATP2B1 encoded by the SLCO2B1. We evaluated the effects of six non‐synonymous (c.1175C>T, c.1457C>T, c.43C>T, c.935G>A, c.601G>A, and c.644A>T) polymorphisms and one promoter (g.‐282G>A) polymorphism on the pharmacokinetics of montelukast. A single dose of 10 mg montelukast was administered in 24 healthy subjects. Its levels were measured up to 24 hours and a pharmacokinetic analysis was performed based on the SLCO2B1 polymorphisms. We did not encounter subjects with c.1175C>T, c.43C>T, or c.644A>T polymorphisms. The remaining SLCO2B1 polymorphisms did not affect plasma levels of montelukast, and pharmacokinetic parameters of montelukast did not differ among genotype groups. Oral clearance results were as follows: (1) 3.3 L/h for c.935GG, 3.0 L/h for c.935GA, and 3.5 L/h for c.935AA; (2) 3.4 L/h for c.1457CC, 2.9 L/h for c.1457CT, and 3.2 L/h for c.1457TT; (3) 3.2 L/h for c.601GG, 3.4 L/h for c.601GA, and 3.4 L/h for c.601AA; (4) 3.2 L/h for g.‐282GG, 3.4 L/h for g.‐282GA, and 3.2 L/h for g.‐282AA. The findings suggest that SLCO2B1 polymorphisms do not affect the pharmacokinetics of montelukast and that SLCO2B1 polymorphisms appear to be a minor determinant of inter‐individual variability of montelukast.
Moonlight affects mRNA abundance of arylalkylamine N‐acetyltransferase in the retina of a lunar‐synchronized spawner, the goldlined spinefoot
Authors: Kashiwagi Tomomi , Park Yong‐Ju , Park Ji‐Gweon , Imamura Satoshi , Takeuchi Yuki , Hur Sung‐Pyo , Takemura Akihiro 
Published: August 2013

AbstractMelatonin synthesis in the pineal gland and retina shows a rhythmic fashion with high levels at night and is controlled by a rate‐limiting enzyme, arylalkylamine N‐acetyltransferase (AANAT). A previous study revealed that moonlight suppresses the plasma melatonin levels of the goldlined spinefoot (Siganus guttatus), which exhibits a lunar cycle in its reproductive activity and repeats gonadal development toward and spawning around the first quarter moon. Whether the retina of this species responds to moonlight is unknown. To clarify the photoperceptive ability of this species, we aimed to clone the full‐length cDNA of Aanat1 (sgAanat1) from the retina and examine its transcriptional pattern under several daylight and moonlight regimes. The full‐length sgAanat1 cDNA (1,038 bp) contained a reading frame encoding a protein of 225 amino acids, which was highly homologous to AANAT1 of other teleosts. Reverse transcription‐polymerase chain reaction (PCR) analysis revealed that among the tissues tested, sgAanat1 fragments were expressed exclusively in the retina. Real‐time quantitative PCR analysis revealed that sgAanat1 fluctuated with high abundance at night under light–dark cycle and at subjective night under constant darkness, but not under constant light. These results suggest that sgAanat1 is regulated by both the external light signal and internal clock system. The abundance of sgAanat1 in the retina was higher at the culmination time around new moon than full moon phase. Additionally, exposing fish to brightness around the full moon period suppressed sgAanat1 mRNA abundance. Thus, moonlight is perceived by fish and has an impact on melatonin fluctuation in the retina. J. Exp. Zool. 319A: 505–516, 2013. © 2013 Wiley Periodicals, Inc.
Changes in glucose and carnitine levels and their transporters in utero‐tubal junction in relation to sperm storage in the vespertilionid bat, Scotophilus heathi
Authors: Roy Vikas Kumar , Krishna Amitabh 
Published: August 2013

ABSTRACTProlonged sperm storage over winter is a common feature of reproduction in some bats. In order to understand how sperm storage in the female genital tract of the vespertilionid bat, Scotophilus heathi (Greater yellow bat), is controlled, we compared concentrations of glucose and the fatty‐acid carrier carnitine in the blood, and carnitine concentrations and levels of expression of the glucose transporters (GLUTs) and the carnitine transporter OCTN2 in the utero‐tubal junction of females during non‐storage (early winter) and sperm‐storage periods (late winter‐early spring). During the sperm‐storage period (December–January) blood glucose concentrations declined, as did the expression of GLUT3 and GLUT5 in the utero‐tubal junction. At the same time there were increases in the concentration of carnitine, and expression of OCTN2 and hormone‐sensitive lipase (HSL) in the utero‐tubal junction. These results suggest that prolonged sperm storage is enhanced by decreased glucose availability but increased free fatty acid availability at the site of sperm storage. Increases in expression of GLUT4 and GLUT8 in late winter suggest a role for these GLUTs in increasing sperm motility prior to fertilization. J. Exp. Zool. 319A: 517–526, 2013. © 2013 Wiley Periodicals, Inc.
Geodetic investigation into the deformation of the Salton Trough
Authors: Crowell Brendan W. , Bock Yehuda , Sandwell David T. , Fialko Yuri 
Published: August 2013

AbstractThe Salton Trough represents a complex transition between the spreading center in Baja California and the strike‐slip San Andreas fault system and is one of the most active zones of deformation and seismicity in California. We present a high‐resolution interseismic velocity field for the Salton Trough derived from 74 continuous GPS sites and 109 benchmarks surveyed in three GPS campaigns during 2008–2009 and previous surveys between 2000 and 2005. We also investigate small‐scale deformation by removing the regional velocity field predicted by an elastic block model for Southern California from the observed velocities. We find a total extension rate of 11 mm/yr from the Mesquite Basin to the southern edge of the San Andreas Fault, coupled with 15 mm/yr of left‐lateral shear, the majority of which is concentrated in the southern Salton Sea and Obsidian Buttes and is equivalent to 17 mm/yr oriented in the direction of the San Andreas Fault. Differential shear strain is exclusively localized in the Brawley Seismic Zone, and dilatation rate indicates widespread extension throughout the zone. In addition, we infer clockwise rotation of 10°/Ma, consistent with northwestward propagation of the Brawley Seismic Zone over geologic time.
Edifice strength and magma transfer modulation at Piton de la Fournaise volcano
Authors: Got Jean‐Luc , Peltier Aline , Staudacher Thomas , Kowalski Philippe , Boissier Patrice 
Published: August 2013

AbstractFrom 2003 to 2007, eruptive activity at Piton de la Fournaise was shown to follow cycles, comprising many summit/proximal eruptions and finishing by a distal eruption. GPS measurements evidenced striking asymmetric deformation between its western and eastern flanks. Horizontal displacements recorded during interdistal periods showed a characteristic amplitude at the top of the eastern flank. Displacements recorded at the base of the summit cone showed a bimodal distribution, with low amplitudes during interdistal periods and large ones during distal eruptions. To account for displacement asymmetry, characteristic amplitude, and large flank displacement, we modeled the volcanic edifice using a Drücker‐Prager elastoplastic rheology. Friction angles of 15° and >30° were needed to model the displacements respectively during distal eruptions and interdistal periods; this change shows that strain weakening occurred during distal events. Large plastic displacement that occurred in the eastern flank during distal eruptions relaxed the horizontal elastic stress accumulated during interdistal periods; it triggered summit deflation, horizontal magma transfer, and distal flank eruption and reset the eruptive cycle. Our elastoplastic models also show that simple source geometries may induce large eastern flank displacements that would be explained by a complex geometry in a linear elastic edifice. Magma supply is often thought to control volcano's eruptive activity, with surface deformation reflecting changes in magma supply rate, the volcano's response being linear. Our results bring some evidences that on Piton de la Fournaise time‐space discretization of magma transfer may be the result of the edifice's nonlinear response, rather than changes in magma supply.
Measurement and analysis of ground‐level electric fields and wire‐base current during the rocket‐and‐wire lightning triggering process
Authors: Ngin T. , Uman M. A. , Hill J. D. , Pilkey J. , Gamerota W. R. , Jordan D. M. , Olsen R. C. 
Published: August 2013

AbstractWe present ground‐level electric field intensity and trigger‐wire‐base current measurements in Florida during 33 successful rocket‐and‐wire triggered lightning attempts, those which initiated a sustained upward leader, and 20 unsuccessful attempts. The electric field changes during wire ascent were measured at eight stations between 35 m and 208 m from the launch site while the electric fields produced by precursor discharges at the ascending wire tip were measured at 120 m and 220 m. Both relatively steady trigger wire currents in the milliampere‐range and fast precursor currents in the ampere to hundred‐ampere range were measured at the wire base. A total of 2196 individual precursors were measured in 45 launches with negative charge overhead, with 0 to 225 precursors per launch and each precursor depositing 1 μC to 157 μC of charge at the wire tip. With negative charge overhead, slowly varying currents measured during the wire ascent increased to a maximum value between 3 mA and 10 mA. Positive line charge densities on the trigger wire were inferred from both the wire‐base current and the ground‐level electric field reduction during wire ascent for 38 launches, ranging from 1 μC m−1 near ground to about 100 μC m−1 at 200 m to 300 m aloft. A comparison of successful launches and unsuccessful launches with negative charge overhead shows that successful launches tend to have larger trigger wire line charge densities and larger precursor charge magnitudes, implying larger electric fields aloft. Three unsuccessful triggering attempts were made with positive charge overhead.
The spiral troughs of Mars as cyclic steps
Authors: Smith Isaac B. , Holt John W. , Spiga Aymeric , Howard Alan D. , Parker Gary 
Published: August 2013

AbstractWe combine observations of stratigraphy, morphology, and atmospheric processes to relate the spiral troughs on Mars' polar layered deposits to a class of features known as cyclic steps. Cyclic steps are quasi‐stable, repeating, and upstream‐migrating bed forms that have been studied in terrestrial and submarine environments. The repeating pattern is bounded by hydraulic jumps, which act to stabilize the form. We use radar stratigraphy from the Shallow Radar instrument on Mars Reconnaissance Orbiter to examine trough evolution and constrain lateral transport. We examine visible images from the Thermal Emission Imaging System and observe low‐altitude clouds that we interpret to be the result of katabatic jumps, i.e., the Aeolian counterpart of hydraulic jumps in open channel flow. We then devise a theoretical framework for understanding the origin of the spiral troughs that agree with 10 criteria that should be explained for any scenario to satisfactorily model the spiral troughs. Finally, we use Froude and geometrical analysis to estimate the rate of upstream migration caused by katabatic winds for the spiral troughs.
Relative rates of optical maturation of regolith on Mercury and the Moon
Authors: Braden Sarah E. , Robinson Mark S. 
Published: August 2013

AbstractQuantifying relative differences in regolith optical maturation rates is critical to interpreting multispectral reflectance measurements of airless bodies. In this study, normalized reflectance measurements of crater ejecta blankets and rays are used as indicators of the relative state of regolith maturation on Mercury and the Moon, as well as for a comparison of surface reflectance. Characterization of craters with high‐reflectance ejecta from Lunar Reconnaissance Orbiter Camera and Mercury Dual Imaging System orbital mosaics indicates that the optical maturation rate is up to 4 times faster on Mercury than on the Moon. Observations also show that there are fewer immature craters (per unit area) on Mercury than on the Moon and suggest a younger average age for mercurian rayed craters than for lunar rayed craters. A comparison of crustal reflectance of immature material yields a ratio of 1.9 ± 0.4 for the average photometrically normalized reflectance of lunar material to that of mercurian material. The difference in reflectance is attributed primarily to differences in composition between the lunar highlands and average surface material on Mercury. The new observations of immature craters per unit area and surface reflectance of immature materials are consistent with previous proposals that regolith maturation rates are faster on Mercury than the Moon, and but here we quantify the relative rate from empirical observations for the first time.
On the 3‐Local Profiles of Graphs
Authors: Huang Hao , Linial Nati , Naves Humberto , Peled Yuval , Sudakov Benny 
Published: August 2013

AbstractFor a graph G, let be the probability that three distinct random vertices span exactly i edges. We call the 3‐local profile
of G. We investigate the set of all vectors that are arbitrarily close to the 3‐local profiles of arbitrarily large graphs. We give a full description of the projection of to the plane. The upper envelope of this planar domain is obtained from cliques on a fraction of the vertex set and complements of such graphs. The lower envelope is Goodman's inequality . We also give a full description of the triangle‐free case, i.e. the intersection of with the hyperplane . This planar domain is characterized by an SDP constraint that is derived from Razborov's flag algebra theory.
What Coaches Believe are Best Practices for Coaching: A Qualitative Study of Interviews from Coaches Residing in Asia and Europe
Authors: Gentry William A. , Manning Lisa , Wolf Ali Kyle , Hernez‐Broome Gina , Allen Leigh Whittier 
Published: August 2013

AbstractThe industry of executive and leadership coaching has grown over the past decade, becoming an integral part of many leadership and executive training and development initiatives globally. As a result, research focusing on coaches in Asia and Europe may uncover useful best practices that could inform the field. Such knowledge would enable coaches to better understand how to work better with their client–leaders and can also inform and develop coaching practice and research. The purpose of our qualitative study was to understand, through the interviews of 12 practicing coaches residing in Asia and 19 practicing coaches residing in Europe, what their best practices are in one‐to‐one coaching engagements. Ten best practices from the coaches in Asia and six best practices from the coaches in Europe emerged. Each best practice is discussed as well as limitations, future research, and implications from the findings of our study.
The effects of hypothyroidism on the proximal femoral physis in miniature swine
Authors: Tank Jason C. , Weiner Dennis S. , Jacquet Robin , Childs Dylan , Ritzman Todd F. , Horne Walter I. , Steiner Richard , Morscher Melanie A. , Landis William J. 
Published: August 2013

ABSTRACTAs a potential means of comparing hypothyroidism in humans, this work intended to establish a defined hypothyroid state in immature miniature swine and evaluate specific molecular, cellular, and extracellular responses of their growth plates. Two male, 11‐week‐old Sinclair miniature swine were given 6‐propyl‐2‐thiouracil (PTU) in their water and two other like animals (controls) were provided water without PTU. Blood levels of thyroid stimulating hormone (TSH), triiodothyronine (T3), and thyroxin (T4) were monitored weekly. At 25 weeks of age, the hind limb proximal femoral physes were harvested and divided into portions for histology and reverse transcription‐quantitative polymerase chain reaction (RT‐qPCR) analysis. Compared to controls, swine administered PTU exhibited increased TSH and decreased T3 and T4 serum levels during the study period, features consistent with a hypothyroid state. Compared to controls, hypothyroid swine exhibited structurally altered physes and demonstrated significantly decreased gene expression of aggrecan (p < 0.05) and type X collagen (p ≤ 0.1). This is the first hypothyroid model established in miniature swine and represents a potentially important advance for understanding the condition in humans, in which, like this swine model, there are changes critical to growth plate molecular biology, biochemistry and structure. © 2013 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 31:1986–1991, 2013
The effects of a semi‐rigid ankle brace on a simulated isolated subtalar joint instability
Authors: Choisne Julie , Hoch Matthew C. , Bawab Sebastian , Alexander Ian , Ringleb Stacie I. 
Published: August 2013

AbstractSubtalar joint instability is hypothesized to occur after injuries to the calcaneofibular ligament (CFL) in isolation or in combination with the cervical and the talocalcaneal interosseous ligaments. A common treatment for hindfoot instability is the application of an ankle brace. However, the ability of an ankle brace to promote subtalar joint stability is not well established. We assessed the kinematics of the subtalar joint, ankle, and hindfoot in the presence of isolated subtalar instability, investigated the effect of bracing in a CFL deficient foot and with a total rupture of the intrinsic ligaments, and evaluated how maximum inversion range of motion is affected by the position of the ankle in the sagittal plane. Kinematics from nine cadaveric feet were collected with the foot placed in neutral, dorsiflexion, and plantar flexion. Motion was applied with and without a brace on an intact foot and after sequentially sectioning the CFL and the intrinsic ligaments. Isolated CFL sectioning increased ankle joint inversion, while sectioning the CFL and intrinsic ligaments affected subtalar joint stability. The brace limited inversion at the subtalar and ankle joints. Additionally, examining the foot in dorsiflexion reduced ankle and subtalar joint motion. © 2013 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. Published by Wiley Periodicals, Inc. J Orthop Res 31:1869–1875, 2013
Effects of carbon monoxide on quality, nutrients and antioxidant activity of post‐harvest jujube
Authors: Zhang Shaoying , Li Na 
Published: August 2013

AbstractBackgroundTo effectively extend the shelf life of fresh jujube, carbon monoxide (CO), as a small molecular gas, was applied to fumigate fresh jujube. The quality and antioxidant activity of jujubes fumigated with carbon monoxide at concentrations of 0 (control), 5, 10, 20 and 40 µmol L−1 for 1 h under ambient temperature were investigated.ResultsThe jujube fumigated with 10 µmol L−1 CO showed the best preserving effect amongst all samples. At 30 days, the decay incidence of jujube fumigated with 10 µmol L−1 CO is only two‐thirds of that of control sample; its red index and weight loss rate were 22.8% and 19.4% lower, and its firmness, soluble solids content (SSC) and acidity were 18.7%, 5.4% and 12.2% higher than that of control samples, respectively. Its vitamin C and total flavonoid contents were also the highest. However, no significant difference in total polyphenol content was found. The jujubes treated with 10 µmol L−1 CO exhibited the highest antioxidant activity in terms of reducing power and 2,2‐diphenyl‐1‐(2,4,6‐trinitrophenyl)hydrazyl radical scavenging activity. However, the jujubes fumigated with 40 µmol L−1 CO showed inferior characteristics compared with the control sample.ConclusionFumigating jujubes with proper concentration of CO probably is a potential novel method for post‐harvest jujube preservation in the future. © 2013 Society of Chemical Industry
Maximizing the benefit of minimally invasive surgery
Authors: Mohiuddin Kamran , Swanson Scott J. 
Published: August 2013

AbstractMinimal invasive surgery is an excellent approach for the diagnosis and treatment of a wide range of thoracic disorders that previously required sternotomy or open thoracotomy. The notable benefits of minimal invasive surgery to patients include less postoperative pain, fewer operative and post‐operative major complications, shortened hospital stay, faster recovery times, less scarring, less stress on the immune system, smaller incision, and for some procedures reduced operating time and reduced costs. J. Surg. Oncol. 2013 108:315–319. © 2013 Wiley Periodicals, Inc.
Urea Organogelators – Synthesis and Properties
Authors: Bajaj Natish , Hart Lewis R. , Greenland Barnaby W. , Hayes Wayne 
Published: August 2013

SummaryA series of aromatic ureas have been synthesised and found to exhibit strong gelation or even supergelation characteristics in organic solvents to afford colourless or translucent gel materials. The synthesis of these materials, assessment of their gelation characteristics and rheological properties are reported in this paper.
A “Systematic Approach” to TD‐GPC Data Processing with Band Broadening Correction
Authors: Yau Wallace , Brown Ray , Tyler Phillip , Huang Tianzi , Cong Rongjuan , Klinker Chanda , Hazlitt Lonnie 
Published: August 2013

SummaryThe application of the systematic approach during detector offset determination in triple detector GPC polymer analysis has been shown to result in improvements in terms of the variations observed among the methods for molecular weight distribution determination. More importantly, the remaining, reduced variations are theoretically consistent with axial dispersion corrections proposed in the past. The use of the systematic approach for offset determination coupled with a robust axial dispersion correction offers the potential for completely reconciling the molecular weight results obtained from the three available methods of molecular weight determination in triple detector GPC.