bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sodiophilic Substrate Induces NaF‐Rich Solid Electrolyte Interface for Dendrite‐Free Sodium Metal Anode
Authors: Liu Pei , Miao Licheng , Sun Zhiqin , Chen Xuchun , Jiao Lifang 
Published: June 2024

Abstract3D substrate with abundant sodiophilic active sites holds promise for implementing dendrite‐free sodium metal anodes and high‐performance sodium batteries. However, the heightened electrode/electrolyte side reactions stemming from high specific surface area still hinder electrode structure stability and cycling reversibility, particularly under high current densities. Herein, the solid electrolyte interface (SEI) component is regulated and detrimental side reactions are restrained through the uniform loading of Na–Sn alloy onto a porous 3D nanofiber framework (NaSn‐PCNF). The strong interaction between Na–Sn alloy and PF6− anions facilitates the dissociation of sodium salts and releases more free sodium ions for effective charge transfer. Simultaneously, the modulations of the interfacial electrolyte solvation structure and the construction of a high NaF content SEI layer stabilize the electrode/electrolyte interface. NaSn‐PCNF symmetrical battery demonstrates stable cycling for over 600 h with an ultralow overpotential of 24.5 mV under harsh condition of 10 mA cm−2 and 10 mAh cm−2. Moreover, the full cells and pouch cells exhibit accelerated reaction kinetics and splendid capacity retention, providing valuable insights into the development of advanced Na substrates for high‐energy sodium metal batteries.
Tailoring Multi‐Phenyl Ring Cation for Stable Scalable Hybrid Bismuth Iodide Amorphous Film: Enabling Record Sensitivity and High‐Performance X‐Ray Array Imaging
Authors: Xu Youkui , Li ZhenHua , Shi Chang , Li Yumai , Lei Yutian , Peng Guoqiang , Yu Tengfei , Ren Haiyu , Wang Haoxu , Fan Hengzhong , Zhang Yongsheng , Ci Zhipeng , Wang Qian , Jin Zhiwen 
Published: June 2024

AbstractThe 329‐type bismuth (Bi)‐based metal halide (MH) polycrystalline films have potential to be applied in the new generation of X‐ray imaging technology owing to high X‐ray absorption coefficients and excellent detection properties. However, the mutually independent [Bi2X9]3− units and numerous grain boundaries in the material lead to low carrier transport and collection capabilities, severe ion migration, large dark currents, and poor response uniformity. Here, a new multi‐phenyl ring methyltriphenylphosphonium (MTP) is designed to optimize the energy band structure. For the first time, the coupling between the A‐site cation and [Bi2X9]3− is realized, making it the main contributor to the conduction band minimum (CBM), getting rid of dilemma that carrier transport is confined to [Bi2X9]3−. Further, the preparation of MTP3Bi2I9 amorphous large‐area wafer is achieved by melt‐quenching; the steric hindrance effect improves stability, increases ion migration energy, and promotes response uniformity (14%). Moreover, the amorphous structure takes advantage of A‐site cation participation in the conductivity, achieving a record sensitivity (7601 µC Gy−1 cm−2) and low dark current (≈0.11 nA) in the field of amorphous X‐ray detection, and features low‐temperature large‐area preparation. Ultimately, designing amorphous array imaging devices that exhibit excellent response uniformity and potential imaging capabilities is succeeded here.
Reactive Oxygen Species Responsive Multifunctional Fusion Extracellular Nanovesicles: Prospective Treatments for Acute Heart Transplant Rejection
Authors: Lu Xingyu , Xu Zhanxue , Shu Fan , Wang Yidan , Han Yuhang , Yang Xinrui , Shi Peilin , Fan Chuanqiang , Wang Linglu , Yu Fei , Sun Qipeng , Cheng Fang , Chen Hongbo 
Published: June 2024

AbstractHeart transplantation offers life‐saving treatment for patients with end‐stage heart failure; however, ischemia‐reperfusion injury (IRI) and subsequent immune responses remain significant challenges. Current therapies primarily target adaptive immunity, with limited options available for addressing IRI and innate immune activation. Although plant‐derived vesicle‐like nanoparticles show promise in managing diseases, their application in organ transplantation complications is unexplored. Here, this work develops a novel reactive oxygen species (ROS)‐responsive multifunctional fusion extracellular nanovesicles carrying rapamycin (FNVs@RAPA) to address early IRI and Ly6C+Ly6G− inflammatory macrophage‐mediated rejection in heart transplantation. The FNVs comprise Exocarpium Citri grandis‐derived extracellular nanovesicles with anti‐inflammatory and antioxidant properties, and mesenchymal stem cell membrane‐derived nanovesicles expressing calreticulin with macrophage‐targeting ability. A novel ROS‐responsive bio‐orthogonal chemistry approach facilitates the active targeting delivery of FNVs@RAPA to the heart graft site, effectively alleviating IRI and promoting the polarization of Ly6C+Ly6G− inflammatory macrophages toward an anti‐inflammatory phenotype. Hence, FNVs@RAPA represents a promising therapeutic approach for mitigating early transplantation complications and immune rejection. The fusion‐targeted delivery strategy offers superior heart graft site enrichment and macrophage‐specific targeting, promising improved transplant outcomes.
Ultrastable Zn3N2 Thin Films via Integration of Amorphous GaN Protection Layers
Authors: Sirotti Elise , Böhm Stefan , Sharp Ian D. 
Published: June 2024

AbstractZinc nitride (Zn3N2) is a promising semiconductor for a range of optoelectronic and energy conversion applications, offering a direct bandgap of 1.0 eV, large carrier mobilities, and abundant constituent elements. However, the material is prone to bulk oxidation in ambient environments, which has thus far impeded its practical deployment. While previous approaches have focused on stabilizing the material via integration of ZnO surface layers, these strategies introduce additional challenges regarding elevated processing temperatures and limited control of interface properties. In this study, it is shown that amorphous GaN thin films can serve as highly stable protection layers on Zn3N2 surfaces and can be deposited at the same growth temperature and in the same deposition system as the underlying semiconductor. The GaN‐capped Zn3N2 structures exhibit long‐term stability, surviving over 3 years of exposure to ambient conditions with no discernible alterations in composition, structure, or electrical properties. Notably, the amorphous GaN coatings can even impede Zn3N2 oxidation under prolonged aqueous exposure. Thus, this study offers a solution to stabilize Zn3N2 in ambient conditions, providing a viable pathway to its utilization in robust and high‐performance electronic devices, such as thin film transistors and solar energy conversion systems.
Revolutionizing Aquatic Robotics: Advanced Biomimetic Strategies for Self‐Powered Mobility Across Water Surfaces
Authors: Elhadad Anwar , Gao Yang , Choi Seokheun 
Published: June 2024

AbstractAquatic mobile robots are gaining attention for their potential to revolutionize marine monitoring and exploration within the Ocean Internet of Things. A significant challenge for these untethered robots, especially in remote areas, is achieving energy autonomy. This work presents an innovative self‐sustaining energy system for compact aquatic robots, inspired by biological digestion. Utilizing microbial fuel cell (MFC) technology, organic materials found in aquatic environments are converted into electricity through catalytic redox reactions. To extend the MFC's lifespan, spore‐forming Bacillus subtilis is used as the anodic biocatalyst, leveraging its ability to endure harsh conditions and reactivate in favorable environments, thus enhancing the MFC's longevity. To ensure a steady supply of organic substrates for microbial viability, a biomimetic Janus membrane with asymmetric surface wettability is integrated, enabling selective substrate intake. Additionally, stability mechanisms inspired by water striders allow the robot to move efficiently across water surfaces. The robot mimics the water strider's movement using a motor powered by microbial metabolism, fueled by organic nutrients via the Janus membrane. This study demonstrates the feasibility of using natural processes for technological advancement, setting new benchmarks in the design of autonomous systems.
Airborne Acoustic Vortex End Effector‐Based Contactless, Multi‐Mode, Programmable Control of Object Surfing
Authors: Li Teng , Li Jiali , Bo Luyu , Brooks Michael R. , Du Yingshan , Cai Bowen , Pei Zhe , Shen Liang , Sun Chuangchuang , Cheng Jiangtao , Pan Y. Albert , Tian Zhenhua 
Published: June 2024

AbstractTweezers based on optical, electric, magnetic, and acoustic fields have shown great potential for contactless object manipulation. However, current tweezers designed for manipulating millimeter‐sized objects such as droplets, particles, and small animals exhibit limitations in translation resolution, range, and path complexity. Here, a novel acoustic vortex tweezers system is introduced, which leverages a unique airborne acoustic vortex end effector integrated with a three‐degree‐of‐freedom (DoF) linear motion stage, for enabling contactless, multi‐mode, programmable manipulation of millimeter‐sized objects. The acoustic vortex end effector utilizes a cascaded circular acoustic array, which is portable and battery‐powered, to generate an acoustic vortex with a ring‐shaped energy pattern. The vortex applies acoustic radiation forces to trap and spin an object at its center, simultaneously protecting this object by repelling other materials away with its high‐energy ring. Moreover, The vortex tweezers system facilitates contactless, multi‐mode, programmable object surfing, as demonstrated in experiments involving trapping, repelling, and spinning particles, translating particles along complex paths, guiding particles around barriers, translating and rotating droplets containing zebrafish larvae, and merging droplets. With these capabilities, It is anticipated that the tweezers system will become a valuable tool for the automated, contactless handling of droplets, particles, and bio‐samples in biomedical and biochemical research.
Synergistic Effect of Zn2+ Cation Doping and Te2− Anion Passivation on CsPbBrxI3‐x Nanocrystals for Efficient Perovskite Light‐Emitting Diodes
Authors: Wang Rongwen , Wang Xi , Ma Jinming , Liu Xiangfu , Lu Chengxu , Zhang Jibin , Tu Guoli 
Published: June 2024

AbstractThe challenges of instability and surface defects in CsPbBrxI3‐x nanocrystals (NCs) pose significant limitations on their potential application in high‐performance pure‐red perovskite light‐emitting diodes (PeLEDs). Herein, a synergistic strategy of divalent cation (Zn2+) doping and anion (Te2−) passivation is proposed to solve these issues. Density functional theory analysis reveals that the synergistic effect can not only reduce the formation energy of CsPbBrxI3‐x NCs but also increase theiodide vacancy defect formation energy of CsPbBrxI3‐x NCs. Consequently, the optimized Zn2+/Te2− co‐modified CsPbBrxI3‐x NCs exhibit significantly enhanced stability with a near‐unity photoluminescence efficiency. Pure‐red PeLEDs based on these CsPbBrxI3‐x NCs possess outstanding spectral stability with a maximum external quantum efficiency and luminance of 16.1% and 1397.2 cd m−2, respectively. This synergistic strategy provides a new approach for enhancing the performance of mixed halide perovskite NCs and the corresponding optoelectronic devices.
A Flexible Na‐Ion Supercapacitor/Battery Hybrid Device
Authors: Sharma Gagan Kumar , Pramanik Atin , Puthirath Anand B. , Chattopadhyay Shreyasi , Terlier Tanguy , Pieshkov Tymofii , Saju Sreehari K. , Vajtai Robert , Kaur Davinder , Ajayan Pulickel M. 
Published: June 2024

AbstractA hybrid supercapacitor/battery device is proposed by integrating Na3V2(PO4)2F3 and multi‐walled carbon nanotubes as the battery electrode and carbon nanofiber as a supercapacitor electrode. The device made via the slurry casting of electrode material on foldable thin nickel foils leads to a robust, mechanically flexible sodium‐ion capacitor/battery (supercapattery) as a hybrid energy storage system. The device exhibits a specific capacitance of 136 F g−1 with a corresponding specific capacity of 95 C g−1 at a potential scan rate of 1 mV s−1, a maximum working voltage of 0.70 V, and a power density of 15 kW kg−1 at 2.50 Wh kg−1. Mechanical flexibility tests show practically unperturbed electrochemical properties at significant bending angles of up to 160°, indicating excellent robustness during large‐scale device deformation. The current study offers new avenues to develop energy storage systems for next‐generation portable and wearable energy storage devices that can be integrated into a variety of platforms.
Ferroelectric Order Evolution in Freestanding PbTiO3 Films Monitored by Optical Second Harmonic Generation
Authors: Huang Sisi , Xu Shuai , Ma Cheng , Li Pengzhan , Guo Er‐Jia , Ge Chen , Wang Can , Xu Xiulai , He Meng , Yang Guozhen , Jin Kuijuan 
Published: June 2024

AbstractThe demand for low‐dimensional ferroelectric devices is steadily increasing, however, the thick substrates in epitaxial films impede further size miniaturization. Freestanding films offer a potential solution by eliminating substrate constraints. Nevertheless, it remains an ongoing challenge to improve the stability in thin and fragile freestanding films under strain and temperature. In this work, the structure and ferroelectric order of freestanding PbTiO3 (PTO) films are investigated under continuous variation of the strain and temperature using nondestructive optical second harmonic generation (SHG) technique. The findings reveal that there are both out‐of‐plane and in‐plane domains with polarization along out‐of‐plane and in‐plane directions in the orthorhombic‐like freestanding PTO films, respectively. In contrast, only out‐of‐plane domains are observed in the tetragonal epitaxial PTO films. Remarkably, the ferroelectricity of freestanding PTO films is strengthened under small uniaxial tensile strain from 0% up to 1.66% and well‐maintained under larger biaxial tensile strain up to 2.76% along the [100] direction and up to 4.46% along the [010] direction. Moreover, a high Curie temperature of 630 K is identified in 50 nm thick freestanding PTO films by wide‐temperature‐range SHG. These findings provide valuable understanding for the development of the next‐generation electronic nanodevices with flexibility and thermostability.
Aloperine Suppresses Cancer Progression by Interacting with VPS4A to Inhibit Autophagosome‐lysosome Fusion in NSCLC
Authors: Guo Weina , Zhou Haifeng , Wang Jingbo , Lu Junjie , Dong Yalan , Kang Zhenyu , Qiu Xiaoyuan , Ouyang Xiaohu , Chen Qianyun , Li Junyi , Cheng Xiang , Du Keye , Li Mingyue , Lin Zhihao , Jin Min , Zhang Lei , Sarapultsev Alexey , Shi Kuangyu , Li Fangfei , Zhang Ge , Wu Kongming , Rong Yueguang , Heissmeyer Vigo , Liu Yue , Li Yunlun , Huang Kun , Luo Shanshan , Hu Desheng 
Published: June 2024

AbstractAloperine (ALO), a quinolizidine‐type alkaloid isolated from a natural Chinese herb, has shown promising antitumor effects. Nevertheless, its common mechanism of action and specific target remain elusive. Here, it is demonstrated that ALO inhibits the proliferation and migration of non‐small cell lung cancer cell lines in vitro and the tumor development in several mouse tumor models in vivo. Mechanistically, ALO inhibits the fusion of autophagosomes with lysosomes and the autophagic flux, leading to the accumulation of sequestosome‐1 (SQSTM1) and production of reactive oxygen species (ROS), thereby inducing tumor cell apoptosis and preventing tumor growth. Knockdown of SQSTM1 in cells inhibits ROS production and reverses ALO‐induced cell apoptosis. Furthermore, VPS4A is identified as a direct target of ALO, and the amino acids F153 and D263 of VPS4A are confirmed as the binding sites for ALO. Knockout of VPS4A in H1299 cells demonstrates a similar biological effect as ALO treatment. Additionally, ALO enhances the efficacy of the anti‐PD‐L1/TGF‐β bispecific antibody in inhibiting LLC‐derived subcutaneous tumor models. Thus, ALO is first identified as a novel late‐stage autophagy inhibitor that triggers tumor cell death by targeting VPS4A.
mRNA‐Lipid Nanoparticle‐Mediated Restoration of PTPN14 Exhibits Antitumor Effects by Overcoming Anoikis Resistance in Triple‐Negative Breast Cancer
Authors: Li Wei , Huang Masha , Wu Zhaoping , Zhang Yu , Cai Ying , Su Juncheng , Xia Jia , Yang Fan , Xiao Desheng , Yang Wen , Xu Yingjie , Liu Zhaoqian 
Published: June 2024

AbstractTriple‐negative breast cancer (TNBC) poses a challenging prognosis due to early metastasis driven by anoikis resistance. Identifying crucial regulators to overcome this resistance is vital for improving patient outcomes. In this study, a genome‐wide CRISPR/Cas9 knockout screen in TNBC cells has identified tyrosine‐protein phosphatase nonreceptor type 14 (PTPN14) as a key regulator of anoikis resistance. PTPN14 expression has shown a progressive decrease from normal breast tissue to metastatic tumors. Overexpressing PTPN14 has induced anoikis and inhibited cell proliferation in TNBC cells, while normal human breast cells are unaffected. Mechanistically, PTPN14 is identified as a key factor in dephosphorylating breast cancer antiestrogen resistance 3, a novel substrate, leading to the subsequent inhibition of PI3K/AKT and ERK signaling pathways. Local delivery of in vitro transcribed PTPN14 mRNA encapsulated by lipid nanoparticles in a TNBC mouse model has effectively inhibited tumor growth and metastasis, prolonging survival. The study underscores PTPN14 as a potential therapeutic target for metastatic TNBC, with the therapeutic strategy based on mRNA expression of PTPN14 demonstrating clinical application prospects in alleviating the burden of both primary tumors and metastatic disease.
Cellular Energy Cycle Mediates an Advection‐Like Forward Cell Flow to Support Collective Invasion
Authors: Zhang Jian , Mosier Jenna A. , Wu Yusheng , Waddle Logan , Taufalele Paul V. , Wang Wenjun , Sun Heng , Reinhart‐King Cynthia A. 
Published: June 2024

AbstractCollective cell migration is a model for nonequilibrium biological dynamics, which is important for morphogenesis, pattern formation, and cancer metastasis. The current understanding of cellular collective dynamics is based primarily on cells moving within a 2D epithelial monolayer. However, solid tumors often invade surrounding tissues in the form of a stream‐like 3D structure, and how biophysical cues are integrated at the cellular level to give rise to this collective streaming remains unclear. Here, it is shown that cell cycle‐mediated bioenergetics drive a forward advective flow of cells and energy to the front to support 3D collective invasion. The cell division cycle mediates a corresponding energy cycle such that cellular adenosine triphosphate (ATP) energy peaks just before division. A reaction–advection–diffusion (RAD) type model coupled with experimental measurements further indicates that most cells enter an active division cycle at rear positions during 3D streaming. Once the cells progress to a later stage toward division, the high intracellular energy allows them to preferentially stream toward the tip and become leader cells. This energy‐driven cellular flow may be a fundamental characteristic of 3D collective dynamics based on thermodynamic principles important for not only cancer invasion but also tissue morphogenesis.
Organomagnesia: Reversibly High Carbon Dioxide Uptake by Magnesium Pyrazolates
Authors: Kracht Felix , Rolser Philipp , Preisenberger Paul , Maichle‐Mössmer Cäcilia , Anwander Reiner 
Published: June 2024

AbstractA series of new pyrazolate and mixed pyrazolate/pyrazole magnesium complexes is described and their reactivity toward carbon dioxide is examined. The dimeric complex [Mg(pztBu,tBu)2]2 inserts CO2 instantly and quantitatively forming the tetrameric complex [Mg(CO2·pztBu,tBu)2]4 and monomeric donor‐stabilized [Mg(CO2·pztBu,tBu)2(thf)2]. Complexes of the type [Mgx(pzR,R)2x(HpzR,R)y]n (R = iPr, tBu) engage in similar insertion reactions involving dissociation of the carbamic acid HOOCpzR,R. Even solid polymeric derivatives [Mg(pzR,R)2]n (R = Me, H) react instantaneously and exhaustively with CO2, the resulting [Mg(CO2·pz)2]m featuring a CO2 capacity of 35.7 wt% (8.2 mmol g−1). All described magnesium pyrazolates display completely reversible CO2 uptake in solution and in the solid state, respectively, as monitored via VT 1H NMR and in situ FTIR spectroscopy as well as thermogravimetric analysis. Fluorinated [Mg2(pzCF3,CF3)4(thf)3] does not yield any isolable CO2 insertion product but exhibits the highest activity in the catalytic transformation of epoxides and CO2 to cyclic carbonates.
Analysis and EOT Scaling on Top‐ and Double‐Gate 2D CVD‐Grown Monolayer MoS2 FETs
Authors: Patoary Naim Hossain , Mamun Fahad Al , Xie Jing , Grasser Tibor , Sanchez Esqueda Ivan 
Published: June 2024

Abstract2D layered semiconductors have attracted considerable attention for beyond‐Si complementary metal‐oxide‐semiconductor (CMOS) technologies. They can be prepared into ultrathin channel materials toward ultrascaled device architectures, including double‐gate field‐effect‐transistors (DGFETs). This work presents an experimental analysis of DGFETs constructed from chemical vapor deposition (CVD)‐grown monolayer (1L) molybdenum disulfide (MoS2) with atomic layer deposition (ALD) of hafnium oxide (HfO2) high‐k gate dielectrics (top and bottom). This extends beyond previous studies of DGFETs based mostly on exfoliated (few‐nm thick) MoS2 flakes, and advances toward large‐area wafer‐scale processing. Here, significant improvements in performance are obtained with DGFETs (i.e., improvements in ON/OFF ratio, ON‐state current, sub‐threshold swing, etc.) compared to single top‐gate FETs. In addition to multi‐gate device architectures (e.g., DGFETs), the scaling of the equivalent oxide thickness (EOT) is crucial toward improved electrostatics required for next‐generation transistors. However, the impact of EOT scaling on the characteristics of CVD‐grown MoS2 DGFETs remains largely unexplored. Thus, this work studies the impact of EOT scaling on subthreshold swing (SS) and gate hysteresis using current–voltage (I–V) measurements with varying sweep rates. The experimental analysis and results elucidate the basic mechanisms responsible for improvements in CVD‐grown 1L‐MoS2 DGFETs compared to standard top‐gate FETs.