bluuebunny/crossref_metadata_2025_split huggingface dataset:
Yellow‐Emitting Sr9Sc(PO4)7:Eu2+, Mn2+ Phosphor with Energy Transfer for Potential Application in White Light‐Emitting Diodes
Authors: Dong Xiaoling , Zhang Jiahua , Zhang Liangliang , Zhang Xia , Hao Zhendong , Luo Yongshi 
Published: December 2013

AbstractEu2+–Mn2+ codoped yellow‐emitting Sr9Sc(PO4)7 (SSP) phosphors have been synthesized by solid‐state reactions. The synthesis, structure refinement, and luminescence properties of the obtained phosphor were investigated in detail. The obtained phosphor exhibits a strong excitation band between 250 and 450 nm, matching well with the dominant emission band of a near‐UV light‐emitting‐diode (LED) chip. Upon excitation at 365 nm, the Sr9Sc(PO4)7:Eu2+, Mn2+ phosphor shows strong yellow emissions centered at 510 and 610 nm. The energy transfer mechanism from Eu2+ to Mn2+ in Sr9Sc(PO4)7:Eu2+, Mn2+ has been studied and demonstrated to be a resonant type through a dipole‐quadrupole mechanism based on the decay lifetime data. These results indicate that yellow‐emitting Sr9Sc(PO4)7:Eu2+, Mn2+ can serve as a promising candidate for application in white‐light LEDs.
The Measurement of the Gibbs Energy of Transfer Between Oil and Water Using a Nano‐Carbon Paste Electrode
Authors: Gan Patrick , Lowinsohn Denise , Foord John S , Compton Richard G 
Published: December 2013

AbstractThe use of nano‐carbon paste electrodes for the measurement of Gibbs energies of transfer between oil and aqueous phases is reported. In this method the oil of interest is used as the binder for the nano‐carbon paste electrodes and the molecule of interest is dissolved in the organic or aqueous phase. Voltammetry is performed over a period of time and used to monitor the transfer of the molecule between the two phases. The method is illustrated for the transfer of ferrocenemethanol between water and oil using the ferrocenemethanol / ferroceniummethanol (FcCH2OH/FcCH2OH+) redox couple. Three pairs of voltammetric peaks were observed in a 0.1 M KCl solution when the nano‐carbon paste electrode was modified by dissolution of FcCH2OH in the binder oil: P1 [E=0.23 V, 0.17 V vs. Ag/AgCl (1 M KCl)], P2 [E=0.36 V, 0.32 V vs. Ag/AgCl (1 M KCl)] and P3 [E=0.55 V, 0.46 V vs. Ag/AgCl (1 M KCl)]. These are assigned to the FcCH2OH species existing in the aqueous solution [FcCH2OH(aq)/FcCH2OH+(aq)], originating in the oil (o) [FcCH2OH(o)/FcCH2OH+(aq)] and to oxidation of adsorbed (ads) material on the nano‐carbon [FcCH2OH(ads)] respectively. When supporting electrolyte containing the anions Cl−, NO3− or SCN− was used, an expulsion of the oxidised ferrocene occurred and the difference in midpoint potentials (Emid) between the peaks P1 and P2 observed in these experiments allowed the calculation of the Gibbs energy (ΔG°) of transfer of ferrocenemethanol from water to oil. The average ΔG° value thus obtained was (−12.7±0.2) kJ mol−1. For more hydrophobic anions (X−=PF6−, AsF6−), the electron transfer is coupled to the transfer of the anion into the oil and the ΔG° for the transfer of the ion pair of FcCH2OH+ and X− ions from water to oil was found to be −1.3 and −3.9 kJ mol−1 for PF6− and AsF6− respectively.
Multiplexed Determination of Amino‐Terminal Pro‐B‐Type Natriuretic Peptide and C‐Reactive Protein Cardiac Biomarkers in Human Serum at a Disposable Electrochemical Magnetoimmunosensor
Authors: de Ávila Berta Esteban‐Fernández , Escamilla‐Gómez Vanessa , Lanzone Valentina , Campuzano Susana , Pedrero María , Compagnone Dario , Pingarrón José M. 
Published: December 2013

AbstractA rapid magnetoimmunosensor for the simultaneous determination of two cardiac biomarkers, amino‐terminal pro‐B‐type natriuretic peptide (NT‐proBNP) and C‐reactive protein (CRP), in human serum is described. Specific capture antibodies were covalently immobilized onto carboxylic acid‐modified magnetic beads. The quantification of NT‐proBNP and CRP was performed by using indirect competitive and sandwich configurations, respectively, and horseradish peroxidase‐labeled tracers. The use of dual screen‐printed carbon electrodes allowed the achievement of simultaneous independent amperometric readout for each cardiac biomarker. The developed methodology showed very low limits of detection (0.47 ng mL−1). An international standard for CRP serum spiked with NT‐proBNP was analyzed to evaluate the usefulness of the magnetoimmunosensor.
Participation in biobanks for research by incapacitated adults: review and discussion of current guidelines
Authors: Togni Elena , Dierickx Kris , Porteri Corinna 
Published: December 2013

ObjectiveBiobanks for research and genetic research are important opportunities to create new understanding of complex disorders, such as psychiatric disorders and dementia. The management of biobanks for subjects with psychiatric disorders or dementia raises additional challenges because of the ethical issues regarding the potentially impaired decision‐making capacities of the subjects. The aim of this paper is to study (i) how guidelines address the matter and (ii) how they can be implemented in real research situations with patients suffering from psychiatric disorders and dementia.MethodWe collected and analysed all the relevant guidelines and position papers from national and international organizations dealing with research on biological materials and selected documents mentioning the participation of incapacitated adults in genetic research and biobanks.ResultsEighteen of the 30 analysed documents contain explicit references to adults who are unable to give consent. The main topics addressed by the guidelines are the following: (i) informed consent; (ii) principles of non‐therapeutic research; and (iii) ethics committee review.ConclusionsIn biomedical research, guidelines are an important instrument for facilitating research while promoting subjects' rights and well‐being. Compared with legally binding documents, guidelines are more flexible and can be more easily revised according to evolving research situations and for adaptation to real persons and research settings. We suggest measures to implement the analysed guidelines taking into consideration the case for the participation of patients with neuropsychiatric disorders, who can have impairment of decision‐making capacities without being obviously incompetent, in genetic research and biobanks. Copyright © 2013 John Wiley & Sons, Ltd.
High Glucose Condition Suppresses Neurosphere Formation by Human Periodontal Ligament‐Derived Mesenchymal Stem Cells
Authors: Sawangmake Chenphop , Pavasant Prasit , Chansiripornchai Piyarat , Osathanon Thanaphum 
Published: December 2013

ABSTRACTD‐Glucose serves many roles in cellular functions, but its role in human periodontal ligament‐derived mesenchymal stem cells (hPSLSCs) is yet unknown. Here, the roles of high glucose concentration on neurogenic differentiation by hPDLSCs were investigated. Two‐stage neurogenic induction protocol was employed. Cells were maintained in normal neurogenic induction medium, high glucose condition, or high mannose condition. The results showed that high glucose attenuated neurosphere formation efficiency by hPDLSCs in terms of morphology, neurogenic marker expression, without a deleterious effect on cell viability. Contrastingly, neurosphere‐derived cells matured in high glucose condition exhibited normal neuronal characteristics compared to the control. During neurosphere formation in high glucose, glucose transporters (GLUTs) mRNA levels were significantly decreased, corresponding with the deprivation of cellular glucose uptake. Further, a glucose uptake inhibitor, cytochalasin B, was used to confirm the deleterious effects of glucose uptake deprivation during neurosphere formation. The results demonstrated that deprivation of glucose uptake attenuated neurosphere formation efficiency by hPDLSCs. Together, the results illustrated that high glucose condition attenuated the efficiency of neurosphere formation but not neuronal maturation, which may occur through the downregulation of GLUTs and the reduction of glucose uptake. J. Cell. Biochem. 115: 928–939, 2014. © 2013 Wiley Periodicals, Inc.
Making Numbers Come to Life: Two Scoring Methods for Creativity in Aurora's Cartoon Numbers
Authors: Tan Mei , Mourgues Catalina , Bolden David S. , Grigorenko Elena L. 
Published: December 2013

AbstractAlthough creativity has long been recognized as an important aspect of mathematical thinking, both for the advancement of the field and in students' developing expertise in mathematics, assessments of student creativity in that domain have been limited in number and focus. This article presents an assessment developed for creativity that provides a score for mathematical creativity (MaC) in addition to a score for general creativity in the numeric domain, or what we might call numerical creativity (NuC). We developed different rating scales for each and then explored how each scoring method accounts for the students' mathematical/numerical and creative skills. The psychometric properties for both scoring approaches were examined. Each method was shown to reflect different relationships with other performance tests. In addition, it is proposed that MaC may provide useful insight into students' levels of adaptive expertise in mathematics, as reflected by their ability to apply mathematical knowledge (i.e., language, operations, concepts) to novel situations, representing an informative supplement to performance indicators of math achievement.
Managing Knowledge through Video‐Based Communities
Authors: Kodama Mitsuru 
Published: December 2013

This article proposes that video‐based information network (VIN) tools as a type of social software are a form of infrastructure that promotes the creation of new knowledge that transcends space and time in business activities. The first of two new insights discussed in the article concerns the effects of diverse communication and collaboration provided by VIN tools. Real‐time communication and collaboration enabled by VIN tools, which combine and process images, sound, and data, result in creating particular modes of use of VIN tools specific to the company using them. The second insight is the formation of new business networks and the facilitation of knowledge creation activities through the use of VIN tools.The article considers four elements of information and communications technology (ICT) organizational capability that promote knowledge creation activities through these particular modes of use of VIN tools: ICT application capability, creative dialogue capability, context architect capability, and boundary consolidation capability. It also illustrates that the dynamic relationship of these four elements promotes the formation of business networks and the formation, maintenance, and development of knowledge communities and leads to new knowledge creation. Copyright © 2013 John Wiley & Sons, Ltd.
Going Practical on the Core Competence Concept: On Links, Levels, Time and Context
Authors: Ljungquist Urban 
Published: December 2013

We update the original core competence notions of identification and development to fit high efficient innovation processes in dynamic environments, with aim to progress the concept's applicability for scholars and practitioners.To the core competence concept we add four dimensions previously missing: time (shared history and shared future aims), managerial hierarchy levels (corporate and SBU), innovation development modes and outcome types (radical/incremental and exploitation/exploration), and finally innovation team characteristics and support structure (homogenous/heterogeneous and formal/informal structure).We propose that existing core competencies are ideally explored by homogenous teams managed at the SBU‐level, in structured context, which infers competitive imitation protection. The process starts with identification then progressed by a change in structure: going from formal to informal, which will increase core competence and company performance.Copyright © 2013 John Wiley & Sons, Ltd.
The effects of prematurity on incidence of aspiration following supraglottoplasty for laryngomalacia
Authors: Anderson de Moreno Lauren C. , Matt Bruce H. 
Published: December 2013

ObjectivesTo determine if patients who were born premature have a higher incidence of aspiration following supraglottoplasty compared to patients born full term.Study DesignRetrospective study.MethodsTwo thousand three hundred sixty (2360) patient charts from Riley Hospital for Children were reviewed retrospectively. Patients had already been treated for laryngomalacia with supraglottoplasty by Dr. Bruce Matt. Estimated weeks gestational age at birth was recorded for each patient. Prematurity was stratified as mild (32–36 weeks gestational age [WGA]), very (28–31 WGA), or extremely (<28 WGA). Patients were excluded from the study if they had suspected aspiration with chronic cough, pneumonia, chronic lung disease, or documented aspiration prior to supraglottoplasty.ResultsAs previously shown, 75 patients (3.2%) had aspiration following supraglottoplasty. Twenty of these patients were preterm infants at birth. The rate for aspiration following supraglottoplasty for former premature infants was statistically significant (5.9%, odds ratio = 2.3,P= .0032).ConclusionsChildren who were born premature have a higher rate of postoperative aspiration following supraglottoplasty; however, supraglottoplasty should still be considered as treatment for laryngomalacia as the rate is still relatively low (5.9%).Level of Evidence2b.Laryngoscope, 124:777–780, 2014
Differential analysis of transient increases of serum cTnI in response to handling in rats
Authors: Mikaelian Igor , Dunn Michael E. , Mould Diane R. , Hirkaler Gerard , Geng Wanping , Coluccio Denise , Nicklaus Rosemary , Singer Thomas , Reddy Micaela 
Published: December 2013

AbstractSerum cardiac troponins are the key biomarkers of myocardial necrosis in humans and in preclinical species. The use of ultrasensitive assays for serum cardiac troponin I (cTnI) as a biomarker in safety studies is hampered by interindividual differences. In this study, we investigated the effect of handling procedures on serum cTnI and explored modeling and simulation approaches to mitigate the impact of these interindividual differences. Femoral‐catheterized male Crl:WI(Han) rats (n = 16/group) were left undisturbed in their cages with no handling; subjected to 5 min of isoflurane/O2 anesthesia (A); or placed into a rodent restrainer followed by simulated tail vein injection (RR). Serum cTnI concentrations were assessed over a 24‐h period using an ultrasensitive assay, and the study was repeated for confirmation. The mean serum cTnI concentration pre‐procedure was 4.2 pg/mL, and remained stable throughout the duration of the study in the rats submitted to the A procedure. Serum cTnI concentrations increased transiently after the RR procedure with a median time to maximum concentration (Tmax), of 1 and 2 h and a mean maximum value concentration (Cmax), of 53.0 and 7.2 pg/mL in the initial and repeat studies, respectively. A population pharmacodynamic model identified interindividual, procedure‐ and study‐specific effects on serum cTnI concentrations in rats. It is concluded that a modeling and simulation approach more appropriately describes and statistically analyzes the data obtained with this ultrasensitive assays.
Synthesis, Double‐Helix Formation, and Higher‐Assembly Formation of Chiral Polycyclic Aromatic Compounds: Conceptual Development of Polyketide Aldol Synthesis
Authors: Yamaguchi Masahiko , Shigeno Masanori , Saito Nozomi , Yamamoto Koji 
Published: December 2013

AbstractPolycyclic aromatic compounds are an important group of substances in chemistry, and the study of their properties is a subject of interest in the development of drugs and materials. We have been conducting studies to develop chiral polycyclic aromatic compounds, i.e., helicenes and equatorenes. These helical molecules showed notable aggregate‐forming properties and the capability for chiral recognition exerted by noncovalent bond interactions, which were not observed in compounds with central chirality. Homo‐ and hetero‐double‐helix‐forming helicene oligomers were developed, and the latter self‐assembled to form gels and vesicles. In this article, we describe such hierarchical studies of polycyclic aromatic compounds, which were started from polyketide aldol synthesis.
Battle against RNA oxidation: molecular mechanisms for reducing oxidized RNA to protect cells
Authors: Li Zhongwei , Malla Sulochan , Shin Brian , Li James M. 
Published: December 2013

Oxidation is probably the most common type of damage that occurs in cellular RNA. Oxidized RNA may be dysfunctional and is implicated in the pathogenesis of age‐related human diseases. Cellular mechanisms controlling oxidized RNA have begun to be revealed. Currently, a number of ribonucleases and RNA‐binding proteins have been shown to reduce oxidized RNA and to protect cells under oxidative stress. Although information about how these factors work is still very limited, we suggest several mechanisms that can be used to minimize oxidized RNA in various organisms.This article is categorized under:

RNA Turnover and Surveillance > Turnover/Surveillance Mechanisms
RNA in Disease and Development > RNA in Disease
Nisin production in a chitin-including continuous fermentation system with Lactococcus lactis displaying a cell wall chitin-binding domain
Authors: Şimşek Ömer 
Published: December 2013

Abstract
The limiting factors in the continuous production of nisin are high amount of biomass loss and low dilution rate application. In this study, a chitin-including continuous nisin fermentation system (CICON-FER) was constructed for high volumetric nisin production using nisin producer L. lactis displaying cell wall chitin-binding domain (ChBD) together with chitin in the reactor. In this respect, the highest binding conditions of relevant L. lactis cells to chitin were determined. Then the chitin flakes carrying nisin-producing L. lactis cells were used within the CICON-FER system at different dilution rates (0.1–0.9 h−1) and initial glucose concentrations (20–60 g l−1). The results revealed that the pH 7 conditions and the use of 100 mM sodium phosphate buffer with 0.1 % Tween 20 and Triton X-100 significantly increased the binding capacity of ChBD displaying L. lactis cells to chitin. The constructed CICON-FER system maintained the presence of the ChBD surface displaying L. lactis cells in the reactor system until 0.9 h−1 dilution rate that resulted in a considerably high level of volumetric nisin production and productivity (10,500 IU ml−1 and 9,450 IU ml−1 h−1, respectively) with the combination of a 0.9-h−1 dilution rate and a 40-g l−1 initial glucose concentration. In conclusion, an innovative nisin fermentation system that yielded the highest nisin production thus far and that was feasible for industrial application was created.
Mukoviszidose – eine pleiotrope Ionenkanalerkrankung mit wesentlicher Lungenbeteiligung
Authors: Stanke F. , Tümmler B. , Stuhrmann M. 
Published: December 2013

Zusammenfassung
Die monogene Erkrankung Mukoviszidose wird durch Mutationen im Cystic-fibrosis-transmembrane-conductance-regulator(CFTR)–Gen verursacht und folgt einem rezessiven Erbgang. Die erfolgreiche Diagnose der Erkrankung erfolgt durch eine enge Verzahnung von klinischer Beurteilung, humangenetischer Diagnostik und patientennaher Analyse des CFTR-vermittelten Basisdefekts durch Nachweis von dysfunktionalem CFTR in der Schweißdrüse, der Nasen- oder der Darmschleimhaut. Häufig ist eine Differenzialdiagnose zu CFTR-abhängigen Erkrankungen wie kongenitaler bilateraler Aplasie der Vasa deferentia (CBAVD), Pankreatitis und Bronchiektasen nötig. Für einige CFTR-Mutationen stehen spezifische Therapeutika zur Verfügung, die auf die jeweilige Sequenzvariante zugeschnitten sind und so den CFTR-Mutationsgenotyp direkt klinisch nutzbar machen.
Cyclic cohomology and Baaj-Skandalis duality
Authors: Voigt Christian 
Published: December 2013

AbstractWe construct a duality isomorphism in equivariant periodic cyclic homology analogous to Baaj-Skandalis duality in equivariant Kasparov theory. As a consequence we obtain general versions of the Green-Julg theorem and the dual Green-Julg theorem in periodic cyclic theory.Throughout we work within the framework of bornological quantum groups, thus in particular incorporating at the same time actions of arbitrary classical Lie groups as well as actions of compact or discrete quantum groups. An important ingredient in the construction of our duality isomorphism is the notion of a modular pair for a bornological quantum group, closely related to the concept introduced by Connes and Moscovici in their work on cyclic cohomology for Hopf algebras.
Strong swirl approximation and intensive vortices in the atmosphere
Authors: Klimenko A. Y. 
Published: December 2013

AbstractThis work investigates intensive vortices, which are characterised by the existence of a converging radial flow that significantly intensifies the flow rotation. Evolution and amplification of the vorticity present in the flow play important roles in the formation of the vortex. When rotation in the flow becomes sufficiently strong (this implies the validity of the strong swirl approximation, which has been developed in a series of publications since the 1950s) the previous analysis of the author and the present work determine that further amplification of vorticity is moderated by interactions of vorticity and velocity. This imposes physical constraints on the flow, resulting in the so-called compensating regime, where the radial distribution of the axial vorticity is characterised by the $4/ 3$ and $3/ 2$ power laws. This asymptotic treatment of a strong swirl is based on vorticity equations and involves higher-order terms. This treatment incorporates multi-scale analysis indicating downstream relaxation of the flow to the compensating regime. The present work also investigates and takes into account viscous and transient effects. One of the main points of this work is the applicability of the power laws of the compensating regime to intermediate regions in large atmospheric vortices, such as tropical cyclones and tornadoes.
Acute Coronary Syndrome as a Teachable Moment for Smoking Cessation
Authors: Tofler Geoffrey H. , May Robin , Bartrop Roger , Kirkness Ann , Glinatsis Helen , de Burgh Simon 
Published: December 2013

ABSTRACTIntroduction: Although the teachable moment has been recognised as an important contributor to behaviour change, its role in smoking cessation merits further investigation.Aim: We prospectively evaluated 116 patients hospitalised with a suspected acute coronary syndrome in two tertiary referral hospitals. The patients comprised 84 men and 32 women, aged 54.2 ± 8.5 years, and the final diagnosis was myocardial infarction in 90 and angina in 26.Results/Findings: At one month, the self-reported quit rate was 65%, maintained to 61% at 12 months. The quit rate was greater at one and 12 months for those diagnosed with myocardial infarction (70% and 67%) compared with those who had angina (46% and 40%), p<0.05. The strongest motivators for quitting were the heart attack and the consequences of the diagnosis. Of those who quit at 1 month, 77% did so without additional aids.Conclusions: Hospitalisation with an acute coronary syndrome is associated with a high quit rate, and the diagnosis of heart attack with its potential consequences represents a strong teachable moment to stop smoking. The findings support further investigation of the teachable moment to aid in smoking cessation.