bluuebunny/crossref_metadata_2025_split huggingface dataset:
Research on the Removal Sequence of Arch Rib Assembly Supports for Concrete-Filled Steel Tubular Tied Arch Bridges
Authors: Peng Zhihui , Li Jiaqi 
Published: July 2024

AbstractThe main bridge of the Bayi Bridge project in Yangxin County is a concrete-filled steel tubular tied arch bridge with a calculated span of 127.04 m. The steel pipe arch ribs adopt a dumbbell-shaped cross-section, are manufactured in seven longitudinal sections, and are constructed using the support method. The tie beams are fully prestressed concrete structures. The design guidance plan is to remove the arch rib assembly bracket after completing the arch rib steel pipe concrete construction. Considering that during the construction process of steel pipe concrete top pressure injection, the arch rib assembly support bears a large load and has high safety risks, an optimization plan is proposed to remove the arch rib assembly support first after the steel pipe arch rib assembly is completed, and then top pressure injection of steel pipe concrete. To analyze the optimization effect, a finite element model was established using Midas Civil analysis software to analyze the stress of the two schemes. The results showed that the maximum stress of the steel pipe arch rib in the optimized scheme increased by 11.7 MPa, reaching 128.4 MPa, which is less than the material design strength; The compressive stress of the upper and lower chord concrete decreased by 1.8 MPa and 2.4 MPa respectively; The difference in arch rib deformation has little impact on the selection of the two schemes, and can be solved by setting pre camber; The tensioning of N2 and N7 prestressed steel tendons has little effect on the structural stress, and the optimized plan meets the stress requirements.
Design of the Prefabricated Building PC Component Visualisation Platform
Authors: Liao Guomin , Hu Jing 
Published: July 2024

AbstractThis paper adopts the Django framework and B/S architecture, uses the Web Browser as the client, and applies Pycharm compiler, Python programming language, and MySQL database to design a prefabricated building PC component visualization platform. According to the requirements of prefabricated building PC components, the overall structure of the platform is designed, which is divided into the data layer, the business layer, and the interface layer, mainly achieving 3D visualization of PC component, the data management, the alarm management, the information management, and the equipment maintenance functions. The prefabricated building PC component visualization platform combines data visualization and other technologies to govern visually the storage and management process of PC components, the lifting and installation management process of PC components, and the operation and maintenance management process of PC components.
Design Strategy and Application Research of Small Steel Structure Prefabricated Building
Authors: Du Yihui , Zhang Zijing , Hu Yuchao 
Published: July 2024

AbstractUnder the background of building industrialization, small steel structure prefabricated buildings can achieve quality improvement, efficiency improvement, technological upgrading, resource conservation, and environment friendly demand, so that low-rise houses can get rid of the public impression of cheap and low-tech. Combined with the common problems of small prefabricated buildings in southwest China, this paper sorts out four design strategies for small prefabricated buildings. Based on the case of “Four Seasons of Heshan”, this paper expounds the practical application of design strategies for small steel structure Prefabricated building, including quick construction and environmental protection; Free space and diverse decoration; High safety and complete functionality; Resource cycle, strong sustainability, etc.
A Prefabricated Wall with Automatic Air-Circulation and Dust-Removal Function Based on TRIZ Theory
Authors: Wang Yingjia , Yi Yanan , Man Xianhui 
Published: July 2024

AbstractIn response to the problems of high energy consumption, high maintenance costs, and large space occupation of traditional dust removal equipment, this work utilizes TRIZ theory to innovate and invent a prefabricated wall that automatically circulates air to achieve dust removal function. The wall includes three parts: a solar thermal module, an air circulation dust removal module, and a building solid waste regeneration material insulation module. It uses solar energy to provide power, drive air circulation exchange, and achieve the application of clean energy to reduce dust in the factory building, The effect of reducing summer room temperature and low-carbon heating in winter.
Exogenous Angiotensin-(1–7) Provides Protection Against Inflammatory Bone Resorption and Osteoclastogenesis by Inhibition of TNF-α Expression in Macrophages
Authors: Ren Jiayi , Kitaura Hideki , Noguchi Takahiro , Ohori Fumitoshi , Marahleh Aseel , Ma Jinghan , Kanou Kayoko , Fan Ziqiu , Mizoguchi Itaru 
Published: July 2024

AbstractRenin–angiotensin–aldosterone system plays a crucial role in the regulation of blood pressure and fluid homeostasis. It is reported to be involved in mediating osteoclastogenesis and bone loss in diseases of inflammatory bone resorption such as osteoporosis. Angiotensin-(1–7), a product of Angiotensin I and II (Ang I, II), is cleaved by Angiotensin-converting enzyme 2 and then binds to Mas receptor to counteract inflammatory effects produced by Ang II. However, the mechanism by which Ang-(1–7) reduces bone resorption remains unclear. Therefore, we aim to elucidate the effects of Ang-(1–7) on lipopolysaccharide (LPS)-induced osteoclastogenesis. In vivo, mice were supracalvarial injected with Ang-(1–7) or LPS ± Ang-(1–7) subcutaneously. Bone resorption and osteoclast formation were compared using micro-computed tomography, tartrate-resistant acid phosphatase (TRAP) stain, and real-time PCR. We found that Ang-(1–7) attenuated tumor necrosis factor (TNF)-α, TRAP, and Cathepsin K expression from calvaria and decreased osteoclast number along with bone resorption at the suture mesenchyme. In vitro, RANKL/TNF-α ± Ang-(1–7) was added to cultures of bone marrow-derived macrophages (BMMs) and osteoclast formation was measured via TRAP staining. The effect of Ang-(1–7) on LPS-induced osteoblasts RANKL expression and peritoneal macrophages TNF-α expression was also investigated. The effect of Ang-(1–7) on the MAPK and NF-κB pathway was studied by Western blotting. As a result, Ang-(1–7) reduced LPS-stimulated macrophages TNF-α expression and inhibited the MAPK and NF-κB pathway activation. However, Ang-(1–7) did not affect osteoclastogenesis induced by RANKL/TNF-α nor reduce osteoblasts RANKL expression in vitro. In conclusion, Ang-(1–7) alleviated LPS-induced osteoclastogenesis and bone resorption in vivo via inhibiting TNF-α expression in macrophages.
Radiation-induced cavernoma in pediatric CNS tumors: a systematic review and treatment paradigm
Authors: Vacek Adam , Kaliaperumal Chandrasekaran 
Published: July 2024

Abstract
Purpose
This retrospective systematic literature review aimed to summarize available data regarding epidemiology, etiology, presentation, investigations, differentials, treatment, prevention, monitoring, complications, and prognosis for radiation-induced cavernous malformations (RICMs) in pediatric patients.

Methodology
Review conducted per PRISMA guidelines. Google Scholar, PubMed, Trip Medical Database, and Cochrane Library searched utilizing a keyphrase, articles filtered per inclusion/exclusion criteria, duplicates excluded. Based on criteria, 25 articles identified, 7 further excluded from the systematic data but included in discussion (5 × insufficient data, 2 × other systematic reviews).

Results
Many studies did not contain all explored data. 2487 patients reviewed, 325 later found to have RICM (143 male, 92 female). Mean age at irradiation 7.6 years (range 1.5–19). Mean total radiation dose 56 Gy (12–112). Most common indications for radiation—medulloblastoma 133x, astrocytoma 23x, ependymoma 21x, germinoma 19x. Mean age at RICM diagnosis 18 years (3.6–57). Mean latency to RICM 9.9 years (0.25–41). Most common anatomic locations—temporal 36, frontal 36, parietal 13, basal ganglia 16, infratentorial 20. Clinical presentation—incidental 270, seizures 19, headache 11, focal neurological deficit 7, other 13. 264 patients observed, 34 undergone surgery. RICM bled in 28 patients. Mean follow-up 11.7 years (0.5–50.3). Prognostic reporting highly variable.

Conclusions
From our data, pediatric RICMs appear to display slight male predominance, present about 10 years after initial irradiation in late teen years, and present incidentally in majority of cases. They are mostly operated on when they bleed, with incidental lesions mostly being observed over time. Further prospective detailed studies needed to draw stronger conclusions.
Genomic events stratifying prognosis of early gastric cancer
Authors: Molinari Chiara , Solaini Leonardo , Rebuzzi Francesca , Tedaldi Gianluca , Angeli Davide , Petracci Elisabetta , Prascevic Dusan , Ewald Jan , Rahm Erhard , Canale Matteo , Giovanni Martinelli , Tomezzoli Anna , Bencivenga Maria , Ambrosio Maria Raffaella , Marrelli Daniele , Morgagni Paolo , Ercolani Giorgio , Ulivi Paola , Saragoni Luca 
Published: July 2024

Abstract
Background
The purpose of the study was to conduct a comprehensive genomic characterization of gene alterations, microsatellite instability (MSI), and tumor mutational burden (TMB) in submucosal-penetrating (Pen) early gastric cancers (EGCs) with varying prognoses.

Methods
Samples from EGC patients undergoing surgery and with 10-year follow-up data available were collected. Tissue genomic alterations were characterized using Trusight Oncology panel (TSO500). Pathway instability (PI) scores for a selection of 218 GC-related pathways were calculated both for the present case series and EGCs from the TCGA cohort.

Results
Higher age and tumor location in the upper-middle tract are significantly associated with an increased hazard of relapse or death from any cause (p = 0.006 and p = 0.032). Even if not reaching a statistical significance, Pen A tumors more frequently present higher TMB values, higher frequency of MSI-subtypes and an overall increase in PI scores, along with an enrichment in immune pathways. ARID1A gene was observed to be significantly more frequently mutated in Pen A tumors (p = 0.006), as well as in patients with high TMB (p = 0.027). Tumors harboring LRP1B alterations seem to have a higher hazard of relapse or death from any cause (p = 0.089), being mutated mainly in relapsed patients (p = 0.093).

Conclusions
We found that the most aggressive subtype Pen A is characterized by a higher frequency of ARID1A mutations and a higher genetic instability, while LRP1B alterations seem to be related to a lower disease-free survival. Further investigations are needed to provide a rationale for the use of these markers to stratify prognosis in EGC patients.
Psychotherapeutisches Arbeiten bei Anfallserkrankungen im ambulanten Setting: eine integrative Herangehensweise
Authors: Schöndienst M. , Michaelis R. , Heinen G. , Jokeit H. , Eicher M. , Siegenthaler T. 
Published: July 2024

ZusammenfassungDer vorliegende Artikel befasst sich mit Möglichkeiten der ambulanten psychotherapeutischen Arbeit bei Anfallserkrankungen. Er gibt Anregungen zur Bedeutung des Zeitrahmens in einer Behandlung, zur Vielfalt der Vorgehensmöglichkeiten, die sich aus einer ersten Exploration ergeben können, zur therapeutischen Relevanz der Fremdanamnese und zu den therapeutischen Möglichkeiten verschiedener psychotherapeutischer Ausrichtungen unter Berücksichtigung neuro- und sozialkognitiver Aspekte.
The Limits to Owning One’s Behavior: Husserl’s Phenomenology of Involuntary Action
Authors: Ferencz-Flatz Christian 
Published: July 2024

AbstractThis paper focuses on a lesser-known aspect of Husserl’s theory of action, namely his understanding of “involuntary behavior,” as developed especially in the recently published manuscripts gathered in Studien zur Struktur des Bewusstseins. Specifically, I follow the arguments leading Husserl in these manuscripts to make the peculiar claim that all involuntary behaviors can be appropriated and converted into voluntary action. In reflecting upon this argument I point out the merits of Husserl’s engagement with involuntary acts, which considerably reshape his practical philosophy, but I also highlight some of its important limitations, which originate in a structural shortcoming of Husserl’s theory in general, namely his presupposition of a rigorous parallelism between cognition, emotion, and action. By showing how this ultimately leads to a reductive and phenomenologically inaccurate view of practical experience, I conclude by pointing to some possible ways to overcome these limitations.
The influence of branched polyethyleneimine concentration on the spectroscopic and morphology of BPEI/AuNPs for photocatalytic reduction of 4-nitrophenol
Authors: Abd El-Mongy S. , Seoudi R. , Hussein A. M. 
Published: July 2024

AbstractIn this work, gold nanoparticles (AuNPs) were synthesized and stabilized by branched polyethyleneimine (BPEI) due to their amine groups as a low-cost alternative method. The concentration of BPEI as a critical factor can be used to optimize stable AuNPs with varying sizes. To evaluate BPEI concentrations on surface plasmonic resonance (SPR), size distribution, chemical coordination, and photocatalytic activity of BPEI-AuNPs products, UV–visible, transmission electron microscope, and Fourier transform infrared spectroscopy were used. The SPR bands appeared at 524, 520, and 517 nm as the BPEI concentration increased (10–30 µL), and the band remained stable as BPEI increased. TEM images show a wide range of sizes (polydisperse) for BPEI/AuNPs were formed. According to TEM images, gold nanoparticle sizes were calculated at (18, 12, and 5 nm) for BPEI concentrations 10, 20, and 30 µL. Fourier transform infrared spectroscopy (FTIR) revealed that amine groups from BPEI play an important role in stabilizing AuNPs. For accessing the photocatalytic activity of BPEI-AuNPs, the reduction of 4-nitrophenol (4-NP) by borohydride is a widely used model reaction. As the AuNPs sizes decreased from 18 to 5 nm, the reduction rate was accelerated and the reaction time of 4-NP to 4-AP conversion decreased from 270 to 150 s.
Rock-fall runout simulation using a QGIS plugin along north–west coast of Malta (Mediterranean Sea)
Authors: Sarkar Nabanita , Devoto Stefano , Vandelli Vittoria , Rossi Sofia , Soldati Mauro , Rizzo Angela 
Published: July 2024

AbstractCoastal instability in the form of rock fall is widespread along the northern coasts of Malta and is strictly connected to structural controls, such as lithology and tectonics. The local geological and geomorphological setting combined with extreme weather events, whose spatial and temporal occurrence is enhanced by ongoing climate and land use change, determines rock-fall hazard along the north–west coast of Malta, a hotspot for Mediterranean tourism. The present research portrays the results of a pilot study aimed at analyzing rock-fall runout probability along this stretch of coast. Cliffs and downslope terrains were the object of detailed field surveys. This included the detection of persistent joints in the source areas and the identification of slope-forming materials like debris and boulders present along the downslope terrains. The outcomes of the field surveys and GIS-based processing of topographic information were used for identification of the input parameters for rock-fall runout simulation. The latter was performed using a QGIS based plugin (QPROTO) that allows to determine expected runout extents and assess the rock-fall susceptibility. The result is the characterization and mapping of rock-fall runout probability zones along six investigated sites. The outputs of the research and the replicability of the method can be of interest for authorities aiming at defining risk management actions and undertaking mitigation measures compliant with sustainable development of coastal areas.
Comparative analysis of Sarcopenia in hospitalized elderly: exploring the impact of liver cirrhosis
Authors: Romano A. D. , Cornacchia M. G. , Sangineto M. , Di Gioia G. , Villani R. , Serviddio G. 
Published: July 2024

AbstractThe progressive aging of the population has led to a rise in geriatric pathologies, with sarcopenia, characterized by muscle mass and function loss, becoming a crucial prognostic indicator. This study investigates sarcopenia in elderly hospitalized patients with advanced chronic liver disease (cirrhotic) and non-liver disease patients, comparing their prevalence and exploring correlations with anthropometric and biochemical factors. The cohort of 115 patients, including 50 cirrhotic and 65 non-cirrhotic individuals, exhibited significant comorbidities and a mean age of 78.4 years. Cirrhotic patients presented distinct laboratory parameters indicating liver damage. Applying European Working Group on Sarcopenia in Older People criteria, probable sarcopenia prevalence was similar in cirrhotic (62%) and non-cirrhotic (63%) patients. Stratifying probable sarcopenia into confirmed sarcopenia and dynapenia revealed no significant differences between populations. Correlation analyses demonstrated positive associations between Appendicular Skeletal Muscle Mass (ASM) and anthropometric parameters, malnutrition risk, and grip strength. In cirrhotic patients, muscle mass inversely correlated with liver damage. Odds ratio analysis highlighted the Mini Nutritional Assesment’s (MNA) significant predictive capability for sarcopenia. ROC curve analysis affirmed MNA and biochemical markers' combined use, such as transferrin, albumin, total cholesterol, lymphocyte count and C-reactive protein as a strong predictor. Despite limitations, such as a small sample size, this study underscores the significance of thorough sarcopenia screening in elderly hospitalized patients, especially those with cirrhosis. Indeed, individuals with end-stage liver disease are particularly susceptible to sarcopenia. A more personalized approach utilizing tools like MNA and biochemical markers could prove beneficial. Further research is warranted to validate these findings and inform clinical interventions.
Comparing two crowdsourcing platforms: assessing their potential for mapping Antarctica
Authors: Gulnerman Ayse Giz , Senel Muge , Gokduman Ozan Deniz 
Published: July 2024

AbstractsGeographical data acquisition in Antarctic regions is challenging due to the lack of human habitation, harsh environmental conditions, and limited accessibility. This research explores and evaluates the capability of two crowdsourcing platforms in mapping facilities across Antarctic regions. The study presents crowdsourcing projects related to polar regions in the literature. The methodology section outlines the data acquisition techniques employed by Flickr and Happywhale, and the spatial evaluation methods applied to the collected data. In the implementation and results section, the spatiotemporal potential of the data obtained from the two identified crowdsourced platforms is assessed, and the results based on spatial statistical methods are compared. In the discussion and conclusion section, the contribution of the two identified crowdsourced platforms to mapping activities is evaluated in terms of spatial, temporal, and content differences. This study reveals that Happywhale offers data with higher spatial consistency, considering seasonal representation and spatial autocorrelation. Additionally, content restrictions and reliance on GPS enhance spatial accuracy in Happywhale. At the same time, the liberation of data production leads to lower quality but increased quantity, diversity, and spatial coverage, as observed in Flickr. By comparing two crowdsourced platforms, this study enhances data acquisition and evaluation potential in Antarctica.
FDG-PET in the diagnosis of primary progressive aphasia: a systematic review
Authors: Mirbod Melika , Ayubcha Cyrus , Redden Hyae Won Kim , Teichner Eric , Subtirelu Robert C. , Patel Raj , Raynor William , Werner Thomas , Alavi Abass , Revheim Mona-Elisabeth 
Published: July 2024

AbstractPrimary progressive aphasia (PPA) is a disease known to affect the frontal and temporal regions of the left hemisphere. PPA is often an indication of future development of dementia, specifically semantic dementia (SD) for frontotemporal dementia (FTD) and logopenic progressive aphasia (LPA) as an atypical presentation of Alzheimer’s disease (AD). The purpose of this review is to clarify the value of 2-deoxy-2-[18F]fluoro-D-glucose (FDG)-positron emission tomography (PET) in the detection and diagnosis of PPA. A comprehensive review of literature was conducted using Web of Science, PubMed, and Google Scholar. The three PPA subtypes show distinct regions of hypometabolism in FDG-PET imaging with SD in the anterior temporal lobes, LPA in the left temporo-parietal junction, and nonfluent/agrammatic Variant PPA (nfvPPA) in the left inferior frontal gyrus and insula. Despite the distinct patterns, overlapping hypometabolic areas can complicate differential diagnosis, especially in patients with SD who are frequently diagnosed with AD. Integration with other diagnostic tools could refine the diagnostic process and lead to improved patient outcomes. Future research should focus on validating these findings in larger populations and exploring the therapeutic implications of early, accurate PPA diagnosis with more targeted therapeutic interventions.
Korean flowering cherry (Prunus × yedoensis Matsum.) response to elevated ozone: physiological traits and biogenic volatile organic compounds emission
Authors: Lim Yea Ji , Kwak Myeong Ja , Lee Jongkyu , Kang Dawon , Je Sun Mi , Woo Su Young 
Published: July 2024

AbstractOzone (O3) absorption through leaf stomata disrupts plant physiological processes, prompting various defense mechanisms to mitigate O3-induced harm. This study measured parameters including cell structure, gas exchange, carbon assimilation, lipid peroxidation, and biogenic volatile organic compounds (BVOCs) emissions to evaluate the physiological impact of Prunus × yedoensis under elevated ozone (E-O3) exposure. The seedlings exhibited a slight stimulatory effect during the early phases of E–O3 exposure; however, E–O3 beyond a specific threshold significantly and negatively affected photosynthetic parameters, pigment content, and potential antioxidant capacity, and E–O3 was significantly correlated with the BVOCs emission rate. After three weeks of E–O3 exposure, no significant differences were observed in leaf stomatal appearance in the field emission scanning electron microscopy results, but according to the results of leaf mesophyll cell ultrastructure, grana degradation, membrane decomposition, cell wall thickening, wart–like protrusion formation, and increased plastoglobulus density within the chloroplasts were observed. Chlorophyll content significantly decreased by 38.71%, and solute leakage increased by 20.57% in the E–O3 group. The net photosynthetic rate was almost two times lower with E–O3. In contrast, there were no significant differences in stomatal conductance. In conclusion, E–O3 can induce a hormetic stimulatory effect during the early exposure phase. However, when the critical threshold is exceeded, O3 adversely affects the physiology of P. × yedoensis seedlings. Therefore, E–O3 is a harmful air pollutant that hinders the growth of woody plants, and urban trees require the continuous management of O3 phytotoxicity.