bluuebunny/crossref_metadata_2025_split huggingface dataset:
Decision to Delivery Interval, Perinatal Outcome and Factors Following Emergency Cesarean Section in Southern Ethiopia
Authors: Kassaw Beyene  , Kassahun Fekadu  , Manaye Yihune  , Yosef Alemayehu  , Dagninet Alelign  , Gedife Ashebir  , Biresaw Wassihun  , Abrham Debeb  
Published: July 2024

BACKGROUND: The interval between the decision for an emergency cesarean section and the delivery of the fetus should be made within 30 minutes. In a setting like Ethiopia, the recommendation of 30 minutes is unrealistic. Decision to delivery interval should, therefore, be considered as vital in improving perinatal outcomes. This study aimed to assess the decision to delivery interval, its perinatal outcomes, and associated factors.
METHODS: A facility-based cross-sectional study was employed, and a consecutive sampling technique was used. Both the questionnaire and the data extraction sheet were used, and data analysis was done using a statistical package for social science version 25 software. Binary logistic regression was used to assess the factors associated with decision to delivery interval. P-value < 0.05 level of significance with a 95% Confidence interval was considered statistically significant.
RESULTS: Decision-to-delivery interval below 30 minutes was observed in 21.3% of emergency cesarean sections. Category one (AOR=8.45, 95% CI, 4.66, 15.35), the presence of additional OR table (AOR=3.31, 95% CI, 1.42, 7.70), availability of materials and drugs (AOR=4.08, 95% CI, 1.3, 12.62) and night time (AOR=3.08, 95% CI, 1.04, 9.07) were factors significantly associated. The finding revealed that there was no statistically significant association between prolonged decisions to delivery interval with adverse perinatal outcomes.
CONCLUSION: Decision-to-delivery intervals were not achieved within the recommended time interval. The prolonged decision to delivery interval and adverse perinatal outcomes had no significant association. Providers and facilities should be better equipped in advance and ready for a rapid emergency cesarean section.
Colloidal/Calcified Neurocysticercosis at University Hospital of KSA: A Case Series
Authors: Saima Nazish  , Mohammad Almuhanna  
Published: July 2024

BACKGROUND: Neurocysticercosis (NCC) is considered the most common central nervous system (CNS) helminthic infection. The prevalence of NCC cases in the Middle East has increased in recent years. Thirty-nine cases of NCC were reported between 2003-2011 in the Arabian Peninsula, among, five cases being from the kingdom Saudi Arabia (KSA). Most of the cases reported from the KSA were presented with seizures, and they belonged to expatriate workers or their related contacts. In this case series, we presented three cases of colloidal/calcified NCC.
CASES: Our patients were diagnosed with NCC based on epidemiologic exposure, clinical features, and typical radiological findings. Stool samples for ova and parasites were negative in all three cases. Among these cases, two patients were immigrants and belonged to endemic areas, and third case who is the youngest in this series was a Saudi, without any history of exposure to any source.
RESULTS: The first and the third cases were treated with Albendazole and Dexamethasone. We did not offer any medication regarding NCC in the second case as he had asymptomatic NCC and the disease was inactive so did not mandate anti-helminth medication.
CONCLUSION: NCC in KSA, like in non-endemic countries, is not a rare or unusual infection anymore, presenting with seizures or incidental findings in an asymptomatic state. Vigilant diagnostic protocols with efficient diagnostic tools are required for detecting carriers of the adult form of the parasite. Timely detection of these carriers can avoid further spread and its related complications in the Saudi population.
Histologic and Biochemical Effect of Balanite aegyptiaca Fruit Extract on Alloxan-Induced Diabetes in Wistar Rats
Authors: Solomon Matthias Gamde  , Chinenye J. Ugwah-Oguejiofor  , Aminu Garba  , Godwin O Avwioro  , Akinpelu Moronkeji  , Abdullahi Abiodun Jimoh  
Published: July 2024

BACKGROUND: Diabetes mellitus is among the most prevalent and costly chronic diseases in the world. Unfortunately, immediate prospects for a cure are not available. We aimed to determine the in vivo antidiabetic activity, histologic, and biochemical effect of Balanites aegyptiaca fruit extract on alloxan-induced diabetes in Wistar rats.
METHODS: Thirty-six Wistar rats were allotted into six groups (n=6). Group I was normal control. Group II was induced with diabetes but not treated.Groups III-V were induced with diabetes and treated with 100, 200, and 300 mg/kg extracts while Group VI was treated with Metformin once daily for 14 days. Animals were euthanized, and blood samples were collected for biochemical assays. The liver, kidney, pancreas, and testis were excised and processed by the paraffin wax method.
RESULT: Oral administration of BA extract significantly (P<0.05) reduced blood glucose, liver enzymes, and creatinine levels in diabetic animals. The extract also improved the body weights of diabetic animals and microscopic anatomy of the pancreas, testis, liver, and kidney parenchyma compared to the control.
CONCLUSION: Balanites aegyptiaca phytochemicals reduced blood glucose level and improved the histology of the liver, kidney, pancreas, and testis. Further study is recommended to identify the phytochemicals and mechanism of action.
Factors Associated with Neural Tube Defects among Women Who Gave Birth at Adama Hospital Medical College, Adama, Ethiopia: A Case Control Study
Authors: Dereje Tegene  , Ephrem Mannekulih  
Published: July 2024

BACKGROUND: Neural tube defects (NTDs) occur as a result of incomplete closure of the neural tube by the embryonic age of 26 to 28 days. Addressing factors associated with NTDs would help to identify and prioritize high-risk women, which in turn guides the preventive strategy. The study aimed to identify factors associated with NTDs among women who gave birth or had a second-trimester abortion at Adama Hospital Medical College, from January 1st to December 31st, 2019.
METHODS: Hospital based unmatched case-control study was conducted on 344 women. Data were analyzed with SPSS 20. Descriptive statistics were computed. Binary logistic regression analysis was performed to determine factors associations with NTDs.
RESULTS: The odds of having a fetus with NTDs were 2.19 times higher among women who are not in a marital relationship (AOR = 2.19; 95% CI: 1.13, 4.25). Women with a previous history of Abortion or stillbirth had 3 fold increased risk of having a fetus with NTDs (AOR = 3.05; 95% CI: 1.58, 5.88). Inadequate housing condition nearly doubles the odds of having a fetus with NTDs (AOR = 1.91; 95% CI: 1.20, 3.04). Folic acid or multivitamin supplementation early in pregnancy reduced the odds of having a fetus with NTDs by 43% (AOR = 0.57; 95% CI: 0.35, 0.91)
CONCLUSION: Being not in a marital relationship, previous history of abortion or stillbirth, and living in inadequate housing conditions were risk factors for NTDs, while multivitamins or folic acid supplementation was a protective factor.
Schizodontic Molarization of Mandibular Premolars: A Case Report of Gemination
Authors: Harshata Tirtalli Sathish  , Sharad Kamat  , Mamata Kamat  , Rudrayya S. Puranik  
Published: July 2024

BACKGROUND: Tooth gemination is a single enlarged or joined tooth with a normal tooth count when the anomalous tooth is counted as one. Mandibular second premolars show an elevated variability of crown morphology. Only nine cases of isolated second premolar macrodontia have been reported in the literature.
CASE DESCRIPTION: This case report presents the clinical and radiographic findings and conservative treatment of an atypical and rare case of localized bilateral molarization of mandibular second premolars.
CONCLUSION: Dental professionals should acquire deeper knowledge about anomalies and plan treatment carefully to avoid unexpected complications during dental procedures caused by morphological ignorance.
Der König, sein Held und ihr Drama: Politik und Poetik der klassischen Tragödie
Authors: Haas Claude 
Published: July 2024

Weimarer Klassik und tragédie classique – Die klassische Form und ihre staatsrechtliche Bedeutung Vor dem Hintergrund der epochalen Verunsicherungen des ausgehenden 18. Jahrhunderts stellen sich Goethe und Schiller in ihrer Dramatik den politischen Dimensionen und Abgründen der klassischen französischen Tragödie. Verkappte Staatsgründungen beherrschen ebenso das Geschehen wie der Staatsstreich, der Bürgerkrieg oder der failing state. Eine neue Aktualität gewann das Drama Corneilles und Racines jedoch erst wegen seiner Aufladung der klassischen Form mit staatspolitischen Fundamentalfragen. Das Ringen um eine Regelpoetik und ihre angemessene Umsetzung, vermeintliche Nebensächlichkeiten wie die Einheit der Zeit werden zum Schauplatz genuin politischer Reflexion. Goethe und Schiller verzichten auf eine Restauration der klassischen Form, sie entdecken aber ihre ursprüngliche Energie wieder und verhandeln diese neu. Besonders deutlich zeigt sich dies am dramaturgischen Konflikt zwischen König und Held, der einen bislang weithin übersehenen Grundpfeiler der klassischen Tragödie bildet.
SIYOSIY E’TIQOD: UNING TIZIMI VA FUNKSIYASINING FALSAFIY TAHLILI
Authors: Shernazarov Ravshan 
Published: July 2024

Siyosiy e’tiqod har bir inson va jamiyat hayotida muhim ahamiyat kasb etib, u bizning dunyoqarashimizni, qadriyatlarimizni, hukumat va uning siyosatiga nisbatan pozitsiya va qarashlarimizni ifodalaydi. Mazkur maqola siyosiy e’tiqod va uning mexanizmini tadqiq etishga bag’ishlanib, unda siyosiy e’tiqod funksiyasining falsafiy mohiyati ochib berilgan. Siyosiy e’tiqodning ko’plab omillarga, ijtimoiy mavqe, ta’lim, madaniy va diniy an’analarga bog’liqligi misollar asosida yoritib berilgan. Shuningdek, maqolada siyosiy e’tiqodning shaxs siyosiy jamiyatning siyosiy hayotidagi ishtirokidagi sezilarli ta’sir ko’rsatishidagi roli falsafiy jihatdan asoslab berilgan.
O'ZBEKISTON RESPUBLIKASI VA GERMANIYA FEDERATIV RESPUBLIKASIDA TOVAR BELGILARINI HUQUQIY MUHOFAZA QILISH MASALALARI
Authors: Mukumov Bobur 
Published: July 2024

Ushbu maqolada O'zbekiston Respublikasi va Germaniya Federativ Respublikasida tovar belgilarini huquqiy muhofaza qilishning dolzarb masalalari ko'rib chiqilgan. Tovar belgisining huquqiy tabiati ochib berilgan, "huquqiy muhofaza" va "huquqiy himoya"kabi atamalar tahlil qilingan. Bundan tashqari, tovar belgilarini huquqiy muhofaza qilish bo'yicha ikki mamlakat qonunchiligining qiyosiy huquqiy tahlili o'tkazilgan. Ikki mamlakat qonunchiligining, o'xshash va o'ziga xos xususiyatlari, amaliy misollar keltirilgan. Amaldagi qonunchilikni takomillashtirish bo'yicha amaliy tavsiyalar berilgan.
IMPLEMENTASI KEBIJAKAN MERDEKA BELAJAR KAMPUS MERDEKA (MBKM) DI PERGURUAN TINGGI KEAGAMAAN ISLAM (PTKI)
Authors: Arlina Ulik , Qomar Mujamil , Aziz Abd 
Published: July 2024

Paket kebijakan Kampus Merdeka menjadi langkah awal dari rangkaian kebijakan untuk perguruan tinggi. Hal ini sebagai bagian untuk melepaskan belenggu agar lebih mudah bergerak. Tujuan penelitian ini, mendeskripsikan tentang implementasi kebijakan Merdeka Belajar Kampus Merdeka (MBKM) di Perguruan Tinggi Keagamaan Islam (PTKI). Jenis penelitian ini adalah kualitatif dengan pendekatan analisis deskriptif dan studi literatur (library research). Sumber utama dalam penelitian ini adalah buku, artikel, jurnal maupun sumber bacaan lain yang berhubungan dengan kebijakan Merdeka Belajar Kampus Merdeka (MBKM) di Perguruan Tinggi Keagamaan Islam (PTKI).
Hasil penelitian: 1) Landasan kebijakan Merdeka Belajar Kampus Merdeka (MBKM) di Perguruan Tinggi Keagamaan Islam (PTKI) adalah Peraturan Menteri Pendidikan Nasional No. 3 Th 2020 tentang Standar Nasional Pendidikan Tinggi dan Keputusan Direktur Jenderal Pendidikan Islam No 1591 Th 2022 tentang Petunjuk Teknis Implementasi Merdeka Belajar Kampus Merdeka pada Perguruan Tinggi Keagamaan Islam. 2) Program MBKM di PTKI ada 9 (sembilan) yaitu pertukaran mahasiswa, magang/kerja praktik, asisten mengajar di satuan pendidikan, penelitian/riset, proyek kemahasiswaan, kegiatan wirausaha, studi/proyek independent, membangun desa/kuliah kerja nyata serta moderasi beragama. 3) Manfaat dari pelaksanaan MBKM bagi mahasiswa adalah untuk meningkatkan perluasan jaringan, soft skills mahasiswa, pengembangan kompetensi mahasiswa sejak dini untuk mempersiapkan ketika masuk di dunia kerja dan menambahkan kompetensi tambahan selain pembelajaran di dalam kelas perkuliahan serta mahasiswa menjadi agen/duta (influencer) moderasi beragama. Sehingga dengan adanya Kebijakan MBKM di PTKI maka diharapkan dapat mencetak lulusan yang memiliki kepribadian unggul, kompeten, memiliki jiwa religious calling (panggilan keagamaan) serta mengasah kemampuan sesuai bakat dan minat sebagai persiapan karir masa depan.
Utilizing Blockchain Technology to Modernize Police Operations: Ensuring Security, Transparency, and Efficiency
Authors: Feltovic Milan 
Published: July 2024

This article explores the transformative potential of blockchain technology in police operations, focusing on enhancing security, transparency, and efficiency. Initially recognized for its role in cryptocurrencies, blockchain's inherent immutability and distributed ledger features are now being leveraged to revolutionize data management within law enforcement. The technology ensures the secure, auditable, and tamper-resistant recording of all transactions and data related to police operations, from investigation records to evidence management, ensuring accessibility only to authorized personnel. Key areas examined include the enhancement of security and transparency through blockchain's immutable and distributed records, ensuring data integrity and evidence management by providing an unalterable record of all transactions and data, and improving interoperability among various police departments and agencies. The integration of advanced technologies like Zero-Knowledge Proofs and Layer 2 solutions further strengthens privacy protection and operational speed, contributing to a more efficient and reliable police information system. Practical implementations in police departments worldwide, such as Delhi Police's blockchain initiative for evidence tracking and Dubai Police's collaboration with Cardano Blockchain for secure data sharing, demonstrate significant improvements in transparency, integrity, and security of processes. The article concludes by addressing the ongoing challenges of scalability, interoperability, and privacy, emphasizing the need for continued development and standardization to fully realize blockchain's benefits in modernizing police operations. By evaluating these aspects, the article highlights blockchain's critical role in the digital transformation of law enforcement, promoting greater public trust and cooperation among police units at both national and international levels.
Pengaruh Keterampilan Mengajar Guru Terhadap Motivasi Belajar Siswa SDN 101900 Lubuk Pakam
Authors: Tianovida Siregar  , Risto Luri Pristiani  
Published: July 2024

Penelitian ini bertujuan untuk mengetahui pengaruh keterampilan mengajar guru terhadap motivasi belajar siswa. Penelitian ini dilaksanakan di SDN 101900 Lubuk Pakam. Sampel dalam penelitian ini yaitu kelas V dengan jumlah 30 siswa. Jenis penelitian ini adalah kuantitatif. Alat pengumpulan data yang digunakan untuk mengetahui Keterampilan Mengajar Guru dan Motivasi Belajar Siswa adalah angket yang telah di uji validasi dan realibilitasnya. Kedua berdistribusi normal kerena Variabel keterampilan mengajar guru menunjukkan nilai 0,834 > 0,05 dan variabel motivasi belajar menunjukkan nilai 0,632 > 0,05. Dilakukan uji t pada taraf nyata (∝ =0,05) bahwa ≥ yaitu (0,606 > 0,374) dengan ini membuktikan bahwa diterima, sehingga penulis menyimpulkan bahwa ada pengaruh yang signifikan dari keterampilan mengajar guru terhadap motivasi belajar siswa kelas V di SDN 101900 Lubuk Pakam.
Protective Effect of DHQ-11 against Hypoxia-induced Vasorelaxation
Authors: Zaripov Abdisalim A. , Usmanov Pulat B. , Mirzayeva Yulduzkhon T. , Esimbetov Adilbay T. , Rustamov Shavkat Yu. , Boboev Sadriddin N. , Ibragimov Eldor B. , Qurbonova Shakhnoza B. , Zhurakulov Sherzod N. , Jumayev Inoyat Z. 
Published: July 2024

Hypoxia, or the lack of oxygen, has multiple impacts on the vascular system. The major molecular sensors for hypoxia at the cellular level are hypoxia inducible factor and heme oxygenase. Hypoxia also acts on the vasculature directly conveying its damaging effects through disruption of the control of vascular tone, particularly in the coronary circulation, enhancement of inﬂammatory responses and activation of coagulation pathways. These effects could be particularly detrimental under pathological conditions such as obstructive sleep apnea and other breathing disorders. Introduction: The effect of conjugate 2-(3,4-Dihydroxyphenyl)-6-{[1-(2’-bromo-3’,4’-dimethoxyphenyl)-6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H )-yl]methyl}-3,5,7-trihydroxychroman-4-one (DHQ-11) on hypoxia-induced vasorelaxation was investigated in rat aortic rings using standard organ bath techniques. Materials and methods: Hypoxia was stimulated by a superfusion of aortic rings with a glucose-free Krebs solution bubbled with 95 % N2/5 % CO2. The effect of conjugate DHQ-11 was assessed after a 60- min period of hypoxia on aortic rings precontracted with 50 mm KCl or 1µM phenylephrine (PE). The conjugate DHQ-11 significantly attenuated hypoxia-induced vasorelaxation in the endothelium-intact aortic rings precontracted with KCl or PE in a concentration-dependent manner. Results and discussion: This effect of conjugate DHQ-11 was more potent in aortic rings precontracted with PE than those with KCl where it maximally reduced hypoxia-induced vasorelaxation from 44.7 ± 3.7 to 5.4 ± 3.7 and 33.9 ± 3.4 to 10.8 ± 4.2 %, respectively. The removal of the endothelium attenuated the effect of conjugate DHQ-11 on hypoxia-induced vasorelaxation. Similarly, pretreatment of endothelium-intact aortic rings with L-NAME and methylene blue also attenuated the effect of conjugate DHQ-11 on hypoxia-induced vasorelaxation. Furthermore, the blockade of the ATP-sensitive KATP channel with glibenclamide and the calcium-activated large conductance BKCa channel with TEA also significantly attenuated the effect of conjugate DHQ-11 on hypoxia-induced vasorelaxation. Collectively, these results indicated that conjugate DHQ-11 attenuated the hypoxia-induced vasorelaxation suggesting that it alleviated the oxidative damage of vasculature. Conclusions: This effect of conjugate DHQ-11 possible is mediated through several mechanisms including the blockage of the extracellular Ca2+ entry via the voltage-dependent and receptor-operative Ca2+ channels, as well as inhibition of sarcoplasmic reticulum Ca2+ release via the inositol triphosphate pathway. In addition, endothelium and NO/sGC/cGMP/PKG pathway, as well as KATP and BKCa channels most likely participate in protection by conjugate DHQ-11 against hypoxia-induced vasorelaxation.
COMPARISON OF EFFICACY OF NEEDLE ASPIRATION VERSUS INCISION AND DRAINAGE IN MANAGEMENT OF PERITONSILLAR ABSCESS
Authors: Khokhar Muhammad Riaz , Raza Syed Nusrat , Ayaz Saeed Bin 
Published: July 2024

Objective: To compare the efficacy of needle aspiration versus incision and drainage (I & D) in management of peritonsillar abscess (PTA) in terms of recovery period and recurrence rate. Study Design: Randomized controlled trial. Place and Duration of Study: Otolaryngology departments, Combined Military Hospitals, Rawalpindi and Multan, from January 2011 to January 2013. Material and Methods: Using World Health Organization sample size calculator, a calculated sample of 60 subjects was divided into two equal groups. One group underwent needle aspiration and the other groupunderwent I & D for PTA. The groups were compared for recovery period and recurrence using independent samples t-test and Fisher’s Exact test respectively calculated through SPSS version 20. A p-value <0.05 was considered significant.Results: The mean recovery period was 3.5 ± 1 days for the I & D group and 3.6 ± 1 days for the needle aspiration group (p=0.64). Recurrence rate with I & D was 6.7% and with needle aspiration was 13.7% (p=0.67).Conclusion: Both needle aspiration and I & D are satisfactory surgical options for the treatment of PTA with no significant difference in clinical outcome. However, needle aspiration has an advantage over I & D in terms of minimal morbidity and its ease of performance
Geographic variability in dust and temperature in climate scaling regimes over the Last Glacial Cycle
Authors: Acuña Reyes Nicolás , van't Wout Elwin , Lovejoy Shaun , Lambert Fabrice 
Published: July 2024

Abstract. Temperature and mineral dust records serve as valuable palaeoclimatic indicators for studying atmospheric variability across different temporal scales. In this study, we employed Haar fluctuations to analyse global spatiotemporal atmospheric variability over the Last Glacial Cycle, capturing both high- and low-frequency information within the records, regardless of uniform or non-uniform sampling. Furthermore, we utilised Haar fluctuations to compute fluctuation correlations, thereby enhancing our understanding of palaeoclimate dynamics. Our findings reveal a latitudinal dependency in the transition from macroweather to climate regimes (τc), with polar regions experiencing shorter transitions compared to the tropics and mid-latitudes. These transitions occur at approximately 1/100th of glacial cycle length scales, suggesting a dominant forcing mechanism beyond Milankovitch cycles. Additionally, our analysis shows that polar regions have larger fluctuation amplitudes than lower latitudes as a consequence of the polar amplification effect. Furthermore, fluctuation correlations demonstrate faster synchronisation between the poles themselves compared to lower-latitude sites, achieving high correlation values within 10 kyr. Therefore, our findings suggest a consistent climate signal propagating from the poles to the Equator, representing the first empirical evidence supporting the hypothesis that the poles play a pivotal role as climate change drivers, influencing the variability in climatic transitions worldwide.
El impacto de lo sociocomunitario en el proceso de recuperación de las mujeres en situación de violencia de género: el caso del marco político-normativo español desde la perspectiva autonómica, estatal y europea
Authors: Botija Mercedes , Moriana Gabriela , Sánchez Miret Cristina , Geis Carreras Gemma 
Published: July 2024

La lucha contra la violencia de género es uno de los principales retos para la sociedad en el siglo XXI. Las políticas y legislaciones pueden amparar y promover cambios significativos si son coherentes con las principales evidencias generadas por la comunidad científica internacional como se demuestra en la intervención en Trabajo Social. Por ello, en este artículo, se ha realizado una revisión de la normativa europea, nacional y autonómica, como sustento de las políticas, poniendo el foco en cómo se involucra a la ciudadanía en los procesos de prevención y apoyo a la recuperación de mujeres que sufren violencia de género. Para ello, utilizando las evidencias científicas que ratifican la importancia de lo sociocomunitario en la recuperación de las víctimas, se realizó una extensa revisión legislativa a nivel europeo, nacional y autonómico sobre cómo se explicita esta fundamental variable en la normativa que posteriormente diseñarán las políticas acordes a ellas. Los hallazgos se han relacionado con las evidencias científicas a nivel internacional identificando como elementos exitosos para la involucrar de la ciudadanía en los procesos de recuperación los siguientes aspectos: la participación de la comunidad; interconexión y colaboración; formación a la ciudadanía; diálogo social y redes solidarias y protección al entorno, lo que lamentablemente no es profuso en la normativa analizada. En este artículo, además se plantean recomendaciones en base a las principales fortalezas detectadas, y se hacen propuestas en base a los vacíos identificados en las leyes.