bluuebunny/crossref_metadata_2025_split huggingface dataset:
Are job characteristics associated with patient (de)humanization through the mediation of health providers’ well‐being?
Authors: Capozza Dora , Colledani Daiana , Falvo Rossella 
Published: August 2024

AbstractHealthcare professionals tend to assign a lower human status to patients. We hypothesized that two mindsets are responsible for this attribution: burnout (emotional exhaustion) and work engagement (vigor, dedication, and absorption in one's work). We predicted that exhaustion is negatively related to patient humanizing perceptions (Hypothesis 1), whereas engagement is positively related to them (Hypothesis 2). In addition, we formulated hypotheses on the relationship between job characteristics and humanity perceptions. Based on the Job Demands‐Resources theory, we predicted that resources (e.g., performance feedback) are positively related to humanizing perceptions being positively linked to work engagement (Hypothesis 3a) and negatively linked to exhaustion (Hypothesis 3b). For demands (e.g., work overload), in contrast, they should be negatively related to humanizing perceptions, being positively linked to exhaustion (Hypothesis 4a) and negatively linked to work engagement (Hypothesis 4b). To test the hypotheses, we conducted an online survey. Participants were physicians and nurses (N = 302); a questionnaire was used. The mediation model was estimated by applying path analysis with observed variables. Findings supported the prediction that reduced humanizing perceptions are associated with care providers’ exhaustion (Hypothesis 1). No association was found between humanity perceptions and work engagement. For job aspects, resources were linked to higher humanizing perceptions through the mediation of lower exhaustion (Hypothesis 3b), whereas demands were linked to lower humanizing perceptions through the mediation of higher exhaustion (Hypothesis 4a). Findings suggest that appropriate manipulations of demands and resources may increase patient humanization and improve the therapeutic relationship.
On fraud and certification of green production
Authors: Arguedas Carmen , Blanco Esther 
Published: August 2024

AbstractWe present a novel model of fraud and certification in green production. We focus on settings where firms decide between a green or a standard version of a product together with an advertising strategy that can include fraud. In addition, green firms can choose to certify their production to guarantee the truthfulness of their claims. This results in four production‐advertising possibilities (standard, genuine green, fraudulent green, and certified green), by which we provide new insights about the prevalence of fraud and certification. We characterize the perfect Bayesian equilibrium of the resulting game for given green production costs, certification costs, and consumers' willingness to pay for standard production, and we perform comparative statics for the main parameters of the resulting game. We find that changes in certification and green production costs affect consumers' beliefs differently, whereby increases in certification and decreases in green production costs can broaden the likelihood of fraud. These novel results are robust to different market structures and question the general desirability of public subsidies for promoting green production without accompanying certification.
New report of the rare Sciadonus alphacrucis Melo et al., 2022 (Teleostei, Ophidiiformes, Bythitidae), DNA barcoding, and range extension in the western South Atlantic
Authors: dos Reis Júnior Marcos Roberto , Caixeta Heloisa De Cia , Oliveira Claudio , Melo Marcelo Roberto Souto de 
Published: August 2024

AbstractSciadonus alphacrucis Melo, Gomes, Møller & Nielsen, 2022 is a rare deep‐sea species, previously known from only two specimens collected off São Paulo State, southeastern Brazil, in the western South Atlantic. Herein, we report a new specimen of S. alphacrucis collected on the continental slope off Santa Catarina State, southern Brazil, thereby extending its known distribution by 420 km. Additionally, we provide the new meristic and morphometric data, the molecular identification using sequences of the cytochrome c oxidase subunit I (COI), an updated distribution map, and a discussion of troglomorphic traits.
Fusarium graminearum effector FgEC1 targets wheat TaGF14b protein to suppress TaRBOHD‐mediated ROS production and promote infection
Authors: Shang Shengping , He Yuhan , Hu Qianyong , Fang Ying , Cheng Shifeng , Zhang Cui‐Jun 
Published: August 2024

ABSTRACTFusarium head blight (FHB), caused by Fusarium graminearum, is a devastating disease of wheat globally. However, the molecular mechanisms underlying the interactions between F. graminearum and wheat remain unclear. Here, we identified a secreted effector protein, FgEC1, that is induced during wheat infection and is required for F. graminearum virulence. FgEC1 suppressed flg22‐ and chitin‐induced callose deposition and reactive oxygen species (ROS) burst in Nicotiana benthamiana. FgEC1 directly interacts with TaGF14b, which is upregulated in wheat heads during F. graminearum infection. Overexpression of TaGF14b increases FHB resistance in wheat without compromising yield. TaGF14b interacts with NADPH oxidase respiratory burst oxidase homolog D (TaRBOHD) and protects it against degradation by the 26S proteasome. FgEC1 inhibited the interaction of TaGF14b with TaRBOHD and promoted TaRBOHD degradation, thereby reducing TaRBOHD‐mediated ROS production. Our findings reveal a novel pathogenic mechanism in which a fungal pathogen acts via an effector to reduce TaRBOHD‐mediated ROS production.
In vivo assembly of bacterial partition condensates on circular supercoiled and linear DNA
Authors: Alaoui Hicham Sekkouri , Quèbre Valentin , Delimi Linda , Rech Jérôme , Debaugny‐Diaz Roxanne , Labourdette Delphine , Campos Manuel , Cornet François , Walter Jean‐Charles , Bouet Jean‐Yves 
Published: August 2024

AbstractIn bacteria, faithful DNA segregation of chromosomes and plasmids is mainly mediated by ParABS systems. These systems, consisting of a ParA ATPase, a DNA binding ParB CTPase, and centromere sites parS, orchestrate the separation of newly replicated DNA copies and their intracellular positioning. Accurate segregation relies on the assembly of a high‐molecular‐weight complex, comprising a few hundreds of ParB dimers nucleated from parS sites. This complex assembles in a multi‐step process and exhibits dynamic liquid‐droplet properties. Despite various proposed models, the complete mechanism for partition complex assembly remains elusive. This study investigates the impact of DNA supercoiling on ParB DNA binding profiles in vivo, using the ParABS system of the plasmid F. We found that variations in DNA supercoiling does not significantly affect any steps in the assembly of the partition complex. Furthermore, physical modeling, leveraging ChIP‐seq data from linear plasmids F, suggests that ParB sliding is restricted to approximately 2 Kbp from parS, highlighting the necessity for additional mechanisms beyond ParB sliding over DNA for concentrating ParB into condensates nucleated at parS. Finally, explicit simulations of a polymer coated with bound ParB suggest a dominant role for ParB‐ParB interactions in DNA compaction within ParB condensates.
Spinoza's theory of attributes
Authors: Salgado Borge Antonio 
Published: August 2024

AbstractAny account of Spinoza's understanding of attribute must be able to satisfy his definition criterion; that is, it must coherently accommodate the elements involved in his definition of attribute as “what the intellect perceives of a substance as constituting its essence” (E1d4). But this is not enough. There are several available readings that satisfy this criterion and are mutually incompatible. To know what Spinoza means we must supplement his definition criterion with a criterion aiming at consistency with other principles in his system. With the definition and consistency criteria in the backdrop, the aim of this paper is to offer a critical overview of the current state of the debate on Spinoza's theory of attributes.
Comparison of computer‐assisted sperm analysis and smartphone‐applied sperm analysis for evaluation of frozen–thawed bull semen
Authors: Baştan İlktan 
Published: August 2024

AbstractThis study aims to compare the efficacy of computer‐assisted sperm analysis (CASA) and smartphone‐applied sperm analysis (SASA) in assessing the quality of frozen–thawed bull semen. A total of 75 straws (n = 75) semen samples were used from different production batches of five Holstein bulls. The semen analyses were conducted in three groups: Group I (CASA‐37°C), semen samples were evaluated using the CASA system at 37°C (n = 25); Group II (SASA‐25°C), semen samples were assessed using the SASA system at a temperature of room heat (25°C) (n = 25); and Group III (SASA‐37°C), semen samples were evaluated using the SASA system at 37°C (n = 25). The frozen–thawed bull semen samples were analysed in terms of total motility (TM), progressive motility (PM), immotile, velocity average path (VAP), velocity curve linear (VCL), velocity straight line (VSL) and sperm concentration. There was no significant difference between the groups in terms of spermatozoa concentration (p > .05). However, significant differences among the groups were observed for total motile spermatozoa values (p < .001). Values of progressive motile spermatozoa were lower in Group I and Group II compared to Group III (p < .001). The immotile spermatozoa values were significant between the groups (p < .001) and were found to be proportional to total motile spermatozoa values. Additionally, the VAP, VCL and VSL values were comparable between Group II and Group III, but lower when compared to Group I. In conclusion, the results of the study demonstrate that the Sperm Cell™ system can accurately analyse the concentration of frozen–thawed bull semen. The analyses performed at room temperature indicate a parallelism between the PM value and CASA results. However, it is thought that SASA devices require a series of standardization studies in different semen extenders, different sample concentrations and different animal species, analogous to the standardization evolution process of CASA devices in semen analysis.
Low‐dose intravitreal injection of 4 mg preservative‐free gentamicin and superficial lamellar keratectomy combined with modified Gundersen grafts to control chronic heterochromic iridocyclitis and secondary keratitis in horses
Authors: Charnock Lauren N. , McMullen Richard J. 
Published: August 2024

AbstractObjectiveTo describe a combined treatment approach for heterochromic iridocyclitis and secondary keratitis (HIK) in horses.Animal StudiedA total of 15 horses (16 eyes).ProceduresSixteen eyes from 15 horses (mean age 14.1 years, range 6–26 years) received low‐dose (4 mg) intravitreal preservative‐free gentamicin injection (IVGI) and modified Gundersen grafts with standing sedation and local anesthesia following a clinical diagnosis of HIK. Additional therapies of suprachoroidal triamcinolone (8 mg) injection, episcleral bromfenac implants, and suprachoroidal cyclosporine implants were performed in individual cases. Leptospira titers were also reported when available.ResultsThe most frequent ophthalmic findings were pigmented keratic precipitates (n = 15/16 eyes, 94%), corneal edema (n = 14/16 eyes, 88%), and pigmented cells suspended in the anterior chamber (n = 7/16 eyes, 44%). Postoperative treatment generally consisted of topical and systemic NSAIDs, topical antibiotics, and a topical mydriatic agent. Complications included persistent corneal edema (7/16, 44%), corneal ulceration (6/16, 38%), graft failure requiring revision (2/16, 13%), stromal abscess (1/16, 6%), surgery site infection (1/16, 6%), and suspected retinal degeneration following IVGI (1/16, 6%). One case was enucleated 6 months after treatment (1/16, 6%). Of the 12 eyes with at least 3 months of post‐treatment follow‐up, 10 were comfortable and visual with static or improved symptoms of HIK.ConclusionsThis multimodal treatment approach aims to address both the anterior uveitis and endothelial decompensation frequently seen in horses with HIK. The surgery can be performed under standing sedation. Continued evaluation and long‐term follow‐up is necessary in all horses with HIK.
A new species of Typhlodromips De Leon and a complementary description of T. quaesitus (Wainstein & Beglyarov) (Mesostigmata, Phytoseiidae) from Russia
Authors: Khaustov Vladimir , Döker Ismail , Joharchi Omid , Khaustov Alexander 
Published: August 2024

A new species, Typhlodromips coniferaphilus sp. nov., is described and illustrated based on females collected from various conifers in the Altai Republic and Sakhalin Island, Russia. Moreover, a complementary description of T. quaesitus (Wainstein & Beglyarov) is provided based on females and males collected from various angiosperm plants in the Sakhalin Island, Russia.
COVID-19 related disruption and resilience in immunisation activities in LMICs: a rapid review
Authors: Hartner Anna-Maria , Li Xiang , Gaythorpe Katy 
Published: August 2024

ObjectivesWe conducted a rapid review to determine the extent that immunisation services in low-income and middle-income countries (LMICs) were disrupted by the COVID-19 pandemic and synthesised the factors that can be used to build resilience in future.DesignRapid review reported in accordance with the Preferred reporting for Systematic reviews and Meta-Analyses (PRISMA) guidelines.Data sourcesPubMed and Web of Science were searched through 6 October 2023.Eligibility criteria for selecting studiesWe included studies that focused on disruption to immunisation activities due to the COVID-19 pandemic in LMICs. Outcomes included routine vaccine coverage, supplementary immunisation activities, vaccine doses, timing of vaccination, supply chain changes, and factors contributing to disruption or resilience.Data extraction and synthesisTwo independent reviewers used standardised methods to search, screen and code studies. Quality assessment was performed using a modified version of the Critical Appraisal Skills Programme for qualitative research. Findings were summarised qualitatively.ResultsOf 4978 identified studies, 85 met the eligibility criteria. Included studies showed declines in immunisation activities across LMICs related to the COVID-19 pandemic. These included reductions in achieved routine coverage, cancellation or postponement of campaigns and underimmunised cohorts. Immunisation was most disrupted in the early months of the pandemic; however, recovery varied by country, age-group and vaccine. Though many countries observed partial recovery in 2020, disruption in many countries continued into 2021. It has also been noted that clinician staff shortages and vaccine stock-outs caused by supply chain disruptions contributed to immunisation delays, but that concern over COVID-19 transmission was a leading factor. Key resiliency factors included community outreach and healthcare worker support.ConclusionsThere is limited information on whether reductions in vaccination coverage or delays have persisted beyond 2021. Further research is needed to assess ongoing disruptions and identify missed vaccine cohorts.
Effects of the intermittent theta burst stimulation on gait, balance and lower limbs motor function in stroke: study protocol for a double-blind randomised controlled trial with multimodal neuroimaging assessments
Authors: Huang Guilan , Wang Hewei , Zhao WeiWei , Qian Yao , Yao Yu , Zhang Li , Chen Yating , Song Lianxin , Yang Jinyu , Liu Zhichao , Su Bin , Sun Limin 
Published: August 2024

IntroductionApproximately, 50% of stroke survivors experience impaired walking ability 6 months after conventional rehabilitation and standard care. However, compared with upper limb motor function, research on lower limbs rehabilitation through non-invasive neuromodulation like repetitive transcranial magnetic stimulation (rTMS) has received less attention. Limited evidence exists regarding the effectiveness of intermittent theta-burst stimulation (iTBS), an optimised rTMS modality, on lower limbs rehabilitation after stroke. This study aims to evaluate the effects of iTBS on gait, balance and lower limbs motor function in stroke recovery while also exploring the underlying neural mechanisms using longitudinal analysis of multimodal neuroimaging data.Methods and analysisIn this double-blinded randomised controlled trial, a total of 46 patients who had a stroke will be randomly assigned in a 1:1 ratio to receive either 15 sessions of leg motor area iTBS consisting of 600 pulses or sham stimulation over the course of 3 weeks. Additionally, conventional rehabilitation therapy will be administered following the (sham) iTBS intervention. The primary outcome measure will be the 10 m walking test. Secondary outcomes include the Fugl-Meyer assessment of the lower extremity, Timed Up and Go Test, Functional Ambulation Category Scale, Berg Balance Scale, modified Barthel Index, Mini-Mental State Examination, montreal cognitive assessment, tecnobody balance assessment encompassing both static and dynamic stability evaluations, surface electromyography recording muscle activation of the lower limbs, three-dimensional gait analysis focusing on temporal and spatial parameters as well as ground reaction force measurements, corticomotor excitability tests including resting motor threshold, motor evoked potential and recruitment curves and multimodal functional MRI scanning. Outcome measures will be collected prior to and after the intervention period with follow-up at 3 weeks.Ethics and disseminationThe study has received approval from the Medical Research Ethics Committee of Wuxi Mental Health Center/Wuxi Central Rehabilitation Hospital (no. WXMHCCIRB2023LLky078). Results will be disseminated through peer-reviewed journals and scientific conferences.Trial registration numberChiCTR2300077431.
Compressing the two-particle Green’s function using wavelets: Theory and application to the Hubbard atom
Authors: Moghadas Emin , Dräger Nikolaus , Toschi Alessandro , Zang Jiawei , Medvidović Matija , Kiese Dominik , Millis Andrew J. , Sengupta Anirvan M. , Andergassen Sabine , Di Sante Domenico 
Published: August 2024

AbstractPrecise algorithms capable of providing controlled solutions in the presence of strong interactions are transforming the landscape of quantum many-body physics. Particularly, exciting breakthroughs are enabling the computation of non-zero temperature correlation functions. However, computational challenges arise due to constraints in resources and memory limitations, especially in scenarios involving complex Green’s functions and lattice effects. Leveraging the principles of signal processing and data compression, this paper explores the wavelet decomposition as a versatile and efficient method for obtaining compact and resource-efficient representations of the many-body theory of interacting systems. The effectiveness of the wavelet decomposition is illustrated through its application to the representation of generalized susceptibilities and self-energies in a prototypical interacting fermionic system, namely the Hubbard model at half-filling in its atomic limit. These results are the first proof-of-principle application of the wavelet compression within the realm of many-body physics and demonstrate the potential of this wavelet-based compression scheme for understanding the physics of correlated electron systems.
Prevalence and Associated Factors of Adolescent (15–19 Years) Childbearing in Ghana
Authors: Alhassan Abdul Rauf , Wepeba Tina Wepeamo , Abdulai Kasim , Iddrisu Rhubamatu , Aninanya Gifty Apiung 
Published: August 2024

Background: Adolescent pregnancies continue to be a global issue that affects more high‐income, middle‐income, and then low‐income countries, with the latter experiencing the majority of cases.Aim: The current study looked into the prevalence and variables predicting adolescent childbearing in Ghana.Methodology: Data from the Ghana Multiple Indicator Cluster Survey (MICS) 2017–2018 was used to conduct an analytical cross‐sectional study. The results were examined with SPSS Version 20 (IBM Corp., 2011, and NY). Pearson’s chi‐square and binary logistics analyses were done for associations. A p value of 0.05 was used to determine the analysis’s statistical significance.Results: The total number of adolescents isolated from the 2017 Ghana MICS dataset for this study analysis was 2974. The mean age of the study participants was 16.9 ± 1.4 years with a modal age of 15 years. The prevalence of adolescent childbearing according to this study analysis was 12.3%. The predictive factors for adolescent childbearing were increasing age, decreasing educational level, Volta regional originality, ethnic originality of the study participants, and low economic status.Conclusion: The prevalence of adolescent childbearing in this study was significant and needs the attention of all. Programs to improve adolescent reproductive health must take into account multiple levels of elements, such as the individual, family, community, institutions, national, and international challenges that have an impact on such programs.
Significant Association of PD‐L1 With CD44 Expression and Patient Survival: Avenues for Immunotherapy and Cancer Stem Cells Downregulation in Pancreatic Cancers
Authors: Ali Saleema Mehboob , Adnan Yumna , Ahmad Zubair , Chawla Tabish , Ali S. M. Adnan 
Published: August 2024

Background: Pancreatic cancers are known for their aggressive nature. This aggressiveness may be attributed to the presence of cancer stem cells (CSCs), which promote relapse, metastasis, and resistance to chemotherapy. Targeting CSCs is essential to reverse this aggressiveness in pancreatic malignancies. Literature highlights the association of PD‐L1 expression with CSCs in various cancers, suggesting immunotherapy as a promising therapeutic approach. This study is aimed at investigating the potential of immunotherapy in pancreatic cancers by examining its association with selected CSC marker expression.Method: A retrospective cohort study was conducted involving 56 patients with confirmed diagnoses of pancreatic cancers at Aga Khan University Hospital from January 2015 to October 2022. After exclusions, based on refusal to provide consent or incomplete follow‐up data, 38 patients were enrolled in the study. Immunohistochemistry was performed on formalin‐fixed paraffin‐embedded (FFPE) tumor tissue samples to assess the expression of CSC markers (CD133, CD44, and L1CAM) and immune checkpoint inhibitor marker (PD‐L1). Statistical analysis was employed to determine associations between marker expression, clinical factors, and overall survival.Results: The study revealed that 86.8% of pancreatic cancer cases exhibited positive PD‐L1 expression. Moreover, a significant association of PD‐L1 expression was observed with the presence of CD44 protein (p = 0.030), as well as with the overall survival of patients (p = 0.023).Conclusion: Our findings show a significant association of PD‐L1 with CD44 marker expression as well as patient survival. This research shows the potential to serve as the foundation for investigating the efficacy of immunotherapy in reducing CD44‐expressing CSCs in pancreatic cancer, potentially enhancing patient outcomes.