bluuebunny/crossref_metadata_2025_split huggingface dataset:
A review of adolescent prevention and positive youth development programs in non-English speaking European countries
Authors: Busiol Diego , Shek Daniel T.L. , Lee Tak Yan 
Published: November 2015

AbstractIn this paper, adolescent prevention and positive youth development programs in non-English speaking European countries are reviewed. A survey of the literature published in English, Italian, German, French, and Spanish language between 1994 and 2014 reported a total of 61 programs which have been evaluated by studies using quasi- or true experimental designs. Several observations are highlighted from this review. First, prevention programs outnumber positive youth development programs in Europe. Second, some countries spend significantly more effort and financial support on preventive programs than others. Third, some countries/regions deal with some specific adolescent problems more than other regions. Fourth, there are variations in the use of international standards for implementing and assessing programs as well as disseminating results. Finally, while most of the existing school-based programs are conducted at the local level, there are very few cross-country projects.
Amitriptyline and phenytoin prevents memory deficit in sciatic nerve ligation model of neuropathic pain
Authors: Abdulmajeed Wahab Imam , Ibrahim Ridwan Babatunde , Ishola Azeez Olakunle , Balogun Wasiu Gbolahan , Cobham Ansa Emmanuel , Amin Abdulbasit 
Published: November 2015

Abstract

Background: Phenytoin and amitriptyline are often reported to attenuate pain in chronic conditions. Information on their ability to ameliorate cognitive impairment associated with neuropathic pain remains unclear due to mixed results from studies. This study investigated the effects of phenytoin and amitriptyline on memory deficit associated with neuropathic pain.

Methods: Twenty-eight adult male Wistar rats were randomly divided into four groups: A, B, C, and D (n=7). Groups A, B, C, and D served as sham control, sciatic nerve ligated untreated, sciatic nerve ligated receiving amitriptyline (5 mg/kg), and sciatic nerve ligated receiving phenytoin (10 mg/kg) respectively. Treatments lasted for 14 days, after which both ‘Y’ maze and novel object recognition test (NOR) were performed. On the last day of treatment, the animals were anesthetized and their brain excised, and the prefrontal cortices and sciatic nerve were processed histologically using hematoxylin and eosin.

Results: There was memory impairment in the sciatic nerve ligated untreated group which was statistically significant (p<0.05) when compared to the phenytoin-treated, amitriptyline-treated, and sham control groups using the ‘Y’ maze and NOR tests. Histological quantification showed that the prefrontal cortices of the ligated animals showed increased neural population in comparison to normal control. These increases were significantly marked in the untreated ligated group. Sciatic nerve of untreated ligated group showed high demyelination and axonal degeneration which was ameliorated in the treated animals.

Conclusions: The administration of amitriptyline and phenytoin can ameliorate neuronal injury, demyelination, and memory impairment associated with neuropathic pain in Wistar rats.
Transient congenital hypothyroidism caused by compound heterozygous mutations affecting the NADPH-oxidase domain of DUOX2
Authors: Yoshizawa-Ogasawara Atsuko , Abe Kiyomi , Ogikubo Sayaka , Narumi Satoshi , Hasegawa Tomonobu , Satoh Mari 
Published: November 2015

AbstractHere, we describe three cases of loss-of-function mutations in the nicotinamide adenine dinucleotide phosphate (NADPH)-oxidase (NOX) domain of dual oxidase 2 (
Comparative assessment of five clinical Klebsiella isolates in terms of antibiotic resistance and plasmid profiles / Beş farklı klinik Klebsiella türünün antibiyotik dirençliliği ile plazmid profillerinin karşılaştırmalı olarak değerlendirilmesi
Authors: Avcıoğlu Nermin Hande , Bilkay Işıl Seyis 
Published: November 2015

Abstract
Objective: This study is firstly aimed to biotype and to investigate the antibiotic resistance profiles of Klebsiella strains which were isolated from clinical materials. Also plasmid profile types of Klebsiella species were investigated and the results were compared with each other.
Methods: Klebsiella strains were biotyped by BBL Enterotube II and the antibiotic resistance was tested by Kirby Bauer disc diffusion method. In order to analyse Klebsiella strains genotypically, plasmid DNA’s of them were isolated and generated plasmid profile types determined by Dice coefficients of similarity.
Results: According to biotyping, Klebsiella strains were distributed to five different species (K. pneumoniae, K. ornithinolytica, K. oxytoca, K. terrigena, K. rhinoscleromatis). As well as K. pneumoniae (37.33%) was the most isolated strain, K. terrigena (8.95%) which is not found to be investigated as much as other strains in the literature, was also observed. Additionally, it is determined that Klebsiella strains were resistant to at least one and at most seven antibiotics. With a similarity coefficient of 84%, it was observed that five different Klebsiella species displayed 17 different plasmid profile types. Among these profiles, P1 (52.23%) was the most observed type which exhibits >10 kbp plasmid DNA band and this profile was isolated from all strains.
Conclusion: Finally, it is observed that antibiotic resistance can be due to the plasmid or chromosomal sources and different strains of the same genus may exhibit the same plasmid profile because of the plasmid transformation from one strain to another.
Comparison of total phenolic contents and antioxidant capacities in mint genotypes used as spices / Baharat olarak kullanılan nane genotiplerinin toplam fenolik içerikleri ve antioksidan kapasitelerinin karşılaştırılması
Authors: Elmastaş Mahfuz , Telci İsa , Akşit Hüseyin , Erenler Ramazan 
Published: November 2015

Abstract
Objective: Mint (Mentha spp.) genotypes used as spices are cultivated in Turkey and used for different purposes including herbal tea, spices, the cosmetics industry, and are used in folk medicine. While mint species have been used in traditional practices during humanity’s long history, there is limited research on the comparison of their antioxidant capacity and phenolic contents. This aim of the research is to compare antioxidant capacity and phenolic contents in mint clones to determine superior genotypes for herbal and spice usage and cultivation.
Methods: Antioxidant capacity was evaluated by ferric reducing antioxidant power (FRAP) and trolox equivalent antioxidant capacity (TEAC). Total phenolic content in clones were determined by Folin-Ciocalteu method.
Results: Maximum total phenolic content [28.27±3.95 μg gallic acid equivalent (GAE)/g dry weight (DW)] and FRAP activity 577.09±46.02 μmol Trolox equiv/g DW were obtained from Clone 13 (M. spicata), while M. piperita clones were higher for TEAC activity (800.02±1.10 μmol Trolox equiv/g DW). The results were first records for M. villoso nervata. FRAP and TEAC activities selected clones were correlated with total phenolic content (r=0.77; 0.73 respectively).
Conclusion: According to the results, it can be suggested that Clone 13, Clone 5, (M. spicata) Clone 3 and Clone 8 (M. piperita) are more suitable for use as spice, herbal tea, and antioxidant agents. The clones must be selected for commercial cultivation by the grower and they can be used as spices and herbal teas.
Combined Interactions of Plant Homeodomain and Chromodomain Regulate NuA4 Activity at DNA Double-Strand Breaks
Authors: Su Wen-Pin , Hsu Sen-Huei , Chia Li-Chiao , Lin Jui-Yang , Chang Song-Bin , Jiang Zong-da , Lin Yi-Ju , Shih Min-Yu , Chen Yi-Cheng , Chang Mau-Sun , Yang Wen-Bin , Hung Jan-Jong , Hung Po-Cheng , Wu Wei-Sheng , Myung Kyungjae , Liaw Hungjiun 
Published: November 2015

Abstract
DNA double-strand breaks (DSBs) represent one of the most threatening lesions to the integrity of genomes. In yeast Saccharomyces cerevisiae, NuA4, a histone acetylation complex, is recruited to DSBs, wherein it acetylates histones H2A and H4, presumably relaxing the chromatin and allowing access to repair proteins. Two subunits of NuA4, Yng2 and Eaf3, can interact in vitro with methylated H3K4 and H3K36 via their plant homeodomain (PHD) and chromodomain. However, the roles of the two domains and how they interact in a combinatorial fashion are still poorly characterized. In this study, we generated mutations in the PHD and chromodomain that disrupt their interaction with methylated H3K4 and H3K36. We demonstrate that the combined mutations in both the PHD and chromodomain impair the NuA4 recruitment, reduce H4K12 acetylation at the DSB site, and confer sensitivity to bleomycin that induces DSBs. In addition, the double mutant cells are defective in DSB repair as judged by Southern blot and exhibit prolonged activation of phospho-S129 of H2A. Cells harboring the H3K4R, H3K4R, K36R, or set1Δ set2Δ mutant that disrupts H3K4 and H3K36 methylation also show very similar phenotypes to the PHD and chromodomain double mutant. Our results suggest that multivalent interactions between the PHD, chromodomain, and methylated H3K4 and H3K36 act in a combinatorial manner to recruit NuA4 and regulate the NuA4 activity at the DSB site.
CACERÍA DE SUBSISTENCIA DE MAMÍFEROS EN EL SECTOR ORIENTAL DE LA RESERVA DE BIÓSFERA EL TUPARRO – VICHADA
Authors: Martínez Salas Mónica Del Pilar , López Arévalo Hugo Fernando , Sánchez Palomino Pedro 
Published: November 2015

<p><strong>RESUMEN</strong></p><p class="p2">La cacería de subsistencia ha sido una actividad de vital importancia para las comunidades indígenas como fuente de proteína y venta. Se caracterizó la cacería de subsistencia realizada por comunidades de las etnias Piaroa y Curripaco presentes en la Reserva de Biosfera el Tuparro, por medio de registros de caza durante nueve meses de estudio. Se encontró que no hay diferencias significativas en cuanto a especies y número de individuos cazados entre las dos etnias, siendo Artiodactyla y Rodentia los órdenes con mayor aporte respecto al número de individuos, biomasa y riqueza de especies, lo cual fue similar a otros estudios realizados en el Neotrópico. Los Piaroa cazan más frecuentemente cuando los estudiantes llegan de la ciudad al resguardo, mientras que los Curripaco lo hacen para las reuniones evangélicas. El arte de caza más usado por las comunidades de las dos etnias fue la escopeta. Las etnias estudiadas tienen sus zonas de caza en la Reserva de Biósfera El Tuparro, y en ellas, los Curripaco están aprovechando directamente los recursos de su zona núcleo del Parque Nacional Natural El Tuparro.</p><p class="p2"><strong>ABSTRACT</strong></p><p class="p2">Subsistence hunting has been an activity of vital importance to indigenous communities as a source of protein and sale. We characterized subsistence hunting by Curripaco and Piaroa ethnic groups present in the Tuparro Biosphere Reserve, through hunting records over nine months of study. We found no significant differences in species and number of individuals hunted by the two ethnic groups. The orders Rodentia and Artiodactyla contributed the most in terms of number of individuals, biomass and species richness, which was similar to studies to the Neotropics. The Piaroa hunt more frequently when students return to the community lands from the city, while the Curripaco do so for religious gatherings. The hunting method used most often by both ethnic groups was the shotgun. The hunting areas used by ethnic groups are within the RBT, and the Curripaco are utilizing the resources of the Tuparro Natural National Park, the core area.</p><p class="p3"> </p>
Assessing Uses of Motivated Strategies by Middle School Students Based on Their Learning Styles/Ispitivanje uporabe voljnih strategija učenika viših razreda osnovnih škola na temelju njihovih stilova učenja
Authors: YURT Eyup , AYDIN Mustafa , SAHIN Ismail 
Published: November 2015

AbstractIn this study, middle school students’ motivated strategies for learning were compared based on their learning styles. Four hundred fifty-one senior middle school students participated in this study. The sample comprised 52.3% female students and 47.7% male students. According to the results of the present study, the Concrete Experience and Reflective Observation learning preferences generally exhibit a negative correlation with the motivated strategies for learning whereas the Abstract Conceptualization and Active Experimentation learning styles mostly display a positive correlation with the motivated strategies for learning. Moreover, the students who have the Accommodating and Converging learning styles use motivated strategies for learning more frequently than the students who have the Diverging and Assimilating learning styles.Key words: learning style; learning strategy; middle school student; MSLQ. --- SažetakU ovome su istraživanju uspoređene voljne strategije učenja kojima se na temelju svojih stilova učenja koriste učenici viših razreda osnovnih škola. U istraživanju je sudjelovao četiri stotine pedeset i jedan učenik, od kojih su 52,3% bile djevojčice, a 47,7% dječaci. Rezultati su pokazali da učenici koji pokazuju sklonosti prema načinima učenja utemeljenima na konkretnom iskustvu i refleksivnom promatranju postižu negativnu korelaciju s voljnim strategijama, a da učenici koji se koriste stilovima apstraktne konceptualizacije i aktivnoga eksperimentiranja pokazuju pozitivnu korelaciju s voljnim strategijama učenja. Uz to, učenici koji se koriste akomodirajućim i konvergentnim stilom učenja koriste se voljnim strategijama učenja češće od učenika koji primjenjuju divergentan i asimilirajući stil učenja.Ključne riječi: stil učenja; strategija učenja; učenik višega razreda osnovne škole; Upitnik o voljnim strategijama učenja.
The Efficiency of Student-led and Demonstration Experiments in Initial Physics-Chemistry Education in Primary School/Učinkovitost učeničkih i demonstracijskih pokusa u početnom fizičko-kemijskom obrazovanju učenika razredne nastave
Authors: Cvjeticanin Stanko , Obadovic Dusanka , Rancic Ivana 
Published: November 2015

AbstractContents of materials hold an important place in the realization of the goals and tasks of initial physics and chemistry education in primary school teaching. Fourth grade students (11 years old) adopt basic concepts of various physical and chemical properties of materials. The aim of this paper is to determine the efficiency of student experiments and demonstration experiments in teaching physics and chemistry, in relation to the quality of student knowledge about materials. The research sample consisted of 136 fourth grade students in primary schools in Serbia. Experimental, comparative and descriptive - analytical methods were carried out. The survey instrument was a test (initial, final test and retest were conducted), containing two tasks on each cognitive level (Bloom-Anderson-Kratwohl taxonomy). Students who had independently performed experiments acquired greater knowledge about materials in relation to students to whom experiments have been demonstrated by the teacher. They achieved better results at the level of analysis, evaluation and creation. Key words: demonstration experiments; initial physics and chemistry education; student experiments; student knowledge of material properties.---SažetakSadržaji o materijalima zauzimaju važno mjesto u realizaciji ciljeva i zadataka početnog fizičko-kemijskog obrazovanja u razrednoj nastavi. Učenici 4. razreda (11 godina) usvajaju osnovne pojmove o različitim fizičkim i kemijskim karakteristikama materijala. Cilj rada je utvrđivanje učinkovitosti primjene demonstracijskih i učeničkih pokusa prilikom predavanja sadržaja fizike i kemije, u odnosu na kvalitetu znanja učenika o materijalima. Istraživanje je provedeno na uzorku od 136 učenika 4. razreda osnovnih škola iz Srbije. Korištena je eksperimentalna, komparativna i deskriptivno-analitička metoda. Instrument istraživanja je test (inicijalni, finalni test i retest) koji je sadržavao po dva zadatka putem kojih su se provjeravale sve kognitivne razine (Bloom-Anderson-Kratwohl taksonomija). Učenici koji su samostalno izvodili pokuse ostvarili su veća znanja o materijalima u odnosu na učenike kojima su pokuse demonstrirali učitelji. Postigli su bolje rezultate na razini analize, evaluacije i kreacije. Ključne riječi: demonstracijski pokusi, početno fizičko-kemijsko obrazovanje, učenički pokusi, znanja učenika o osobinama materijala.
Evoking of Spiritual Powers as Foundation for Inclusive Education
Authors: Martišauskienė Elvyda 
Published: November 2015

Inclusive education is based on the idea that all learners have to become participants in the process of (self-) education. This at first sight simple truth causes difficulties because of the variety of inborn human powers and in cases of learners with special needs, in particular. A wide range of strategies have been tested and applied for education of such children in Lithuania and all over the world. Lately significant attention has been laid on inclusive education. However, to achieve the desired outcomes, it is necessary to perceive methodological fundamentals and meaning of inclusive education to a teacher and a learner.
Education is a specific activity, which is directed towards empowerment of an individual to spread own powers. Therefore, it is important to cognise the human nature and to derive the most significant approaches towards education from it. Contemporary science distinguishes three dimensions in the human nature, i.e., physical, psychical and spiritual ones, and their development is considered to be the main goal of a general education school. To enable appropriate attainment of this goal, it is necessary to perceive the essence of every dimension and their interrelation.
The spiritual dimension causes the most serious concern. According to neurologist and psychotherapist V. Frankl, the genesis of the spiritual dimension is supernatural and enables an individual to transcendent the reality and to embody the existential freedom, whereof the real essence is revealed only through the interaction with truth (phenomenon of consciousness). An individual manages own physical and physical powers with the help of own spirit, is able to make decisions, to link own relations and activities with truth in an authentic way. The supreme expression of relations as well as that of spiritual dimension is love. The spiritual dimension is evoked and maturated by love of another individual, therefore, fruitful pedagogical support is always based on it. Moreover, V. Frankl points out that the spirit is never sick.
Such approach to a human being enables us to understand why alpha and omega of education embrace spiritual powers of an individual, why teacher’s spiritual maturation becomes an important factor implementing the paradigm of free education, which contains inclusive education. It is of particular importance to learners with special needs because such education enables them to become full-value participants in the process of self-education in the most appropriate way to them, to experience success and to see the meaning of such activities. Healthy learners also feel advantages of inclusive education because it enables them to self-assess own potential and to envisage their real meaning in a new light. Inclusive education is relevant to teachers as a certain challenge to their spiritual as well as professional capacities, which reveals the in-depth essence of their activities.
Ajuste de una función de producción al sector financiero en Colombia
Authors: Ramírez Vigoya Alejandro 
Published: November 2015

<p>Este trabajo desarrolla en forma pormenorizada la metodología de datos panel para encontrar la mejor especificación econométrica de una función de producción, al comparar la Cobb-Douglas y la translogarítmica con datos del sector financiero colombiano. Se encuentra que la función que mejor se ajusta es la translogarítmica con efectos fijos, lo que indica que, por un lado, existen diferencias significativas en los retornos del capital y del trabajo sobre los ingresos entre bancos y, por otro lado, que existen efectos de segundo orden en el sector y que las elasticidades son variables. Además, se encuentra que el capital y el trabajo tienen productividades marginales decrecientes y estos dos factores son complementarios. Por otro lado, se demuestra que la elasticidad del capital es unitaria y significativa, mientras que el factor trabajo solo complementa al capital, siendo más una herramienta que un aporte significativo para el ingreso de los bancos.</p>
Prácticas de liderazgo en empresas comerciales en Tamaulipas (México)
Authors: Pedraza Melo Norma Angélica , Lavín Verástegui Jesús , Delgado Rivas Gerardo , Bernal González Idolina 
Published: November 2015

<p>El objetivo de este estudio es identificar las prácticas de liderazgo en empresas del sector comercial en Tamaulipas (México). Se aplicó un cuestionario revisado por expertos a una muestra de 84 gerentes. Se usó el análisis factorial exploratorio para identificar la estructura subyacente de las prácticas de liderazgo. Además, los datos fueron analizados con estadística descriptiva, prueba t y ANOVA. Se identificó que las cinco dimensiones del Inventario de Prácticas de Liderazgo (IPL) que están presentes en el ejercicio de liderazgo de la gerencia comercial de las empresas analizadas fueron: desafiar los procesos, inspirar una visión compartida, habilitar a los demás para actuar, modelar el camino y dar aliento al corazón.</p>
Innovación social abierta en el diseño de una política y estrategia de formalización sostenible: un caso colombiano de gobierno colaborativo
Authors: Hernández Iván Darío , Sánchez Oscar 
Published: November 2015

<p>Se presenta este caso de estudio sobre el proyecto de investigación-acción que buscó aportar en la construcción de vías para la solución a la problemática de la informalidad empresarial y laboral en Colombia (2011-2013). Este proyecto utilizó como objeto de estudio la observación y reflexión en el propósito de comprender los determinantes para el éxito o fracaso de un esfuerzo colaborativo, cuando se persiguen objetivos sociales retadores (innovaciones sociales) desde un ámbito mixto (gobierno y sector privado). El proyecto fue desarrollado por el Grupo de Investigación en Economía Evolucionista e Institucional de la Universidad Nacional de Colombia, financiado por Colciencias en alianza con la Cámara de Comercio de Bucaramanga. Se encontró que la capacidad de un equipo interinstitucional para producir resultados que tengan un impacto importante en la sociedad (lograr innovaciones sociales) se construye a partir de la fortaleza de redes interinstitucionales que permiten inferir la emergencia de una nueva metainstitución con la legitimidad, recursos, conocimiento y alineamiento estratégico suficiente para una apropiada armonización de esfuerzos dentro de cada institución.</p>
Índice de desempeño innovador en los subsectores industriales colombianos entre 1996 y 2005
Authors: Manrique Henao Jorge Alonso , Robledo Velásquez Jorge , Lema Tapias Álvaro 
Published: November 2015

<p>En diferentes países se han calculado índices a partir de encuestas de innovación bajo especificaciones planteadas desde el Manual de Oslo de la OCDE. No obstante, las características de la información existente en las realizadas en Colombia en los años 1996 y 2005 no permiten la comparabilidad directa de las variables. Esto llevó a proponer un nuevo índice de desempeño innovador de la industria basado en la metodología del índice de valor de importancia elativizado, utilizado en otros ámbitos como las clasificaciones etnobotánicas. Esta metodología, permite visualizar el fenómeno en los dos momentos de las encuestas realizadas en Colombia y se revela como una herramienta para relacionarlas. Se encontró que el desempeño innovador industrial en el año 1996 fue caracterizado principalmente por la innovación de mercado y organizacional, mientras que en 2005, su principal característica fue la innovación potencial.</p>