bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Eu‐Doped Y‐Based Luminescent Metal–Organic Framework as a Highly Efficient Sensor for Nitroaromatic Explosives
Authors: Singha Debal Kanti , Majee Prakash , Mondal Sudip Kumar , Mahata Partha 
Published: February 2015

AbstractBy an isomorphous substitution strategy, a three‐dimensional metal–organic framework (MOF), [Y1.8Eu0.2(PDA)3(H2O)1]·2H2O (1; PDA = 1,4‐phenylenediacetate), has been synthesized by solvent‐assisted liquid grinding and direct heating. Dehydrated 1 (1′) shows strong red photoluminescence through the antenna effect upon excitation at 240 nm. The red emissive property was used for the visual detection of nitroaromatic explosives in acetonitrile through luminescence quenching. Importantly, 1′ exhibited high sensitivity towards the sensing of 2,4,6‐trinitrophenol (TNP), 1,3‐dinitrobenzene (DNB), 2,4‐dinitrotoluene (DNT), 4‐nitrotoluene (NT), and nitrobenzene (NB) at very low concentrations (0 to 20 μM). The estimated KSV (quenching constant based on linear Stern–Volmer plots) values are in the range 15.9 × 104–1.1 × 104 M–1, which are amongst the highest values known for nitroaromatic‐sensing materials. For 1′, sensing of TNP down to 23 ppb has been achieved.
Complexation of Tetrakis(acetato)chloridodiruthenium with Naphthyridine‐2,7‐dicarboxylate – Characterization and Catalytic Activity
Authors: Lee Chia‐Han , Wu Cai‐Ling , Hua Shao‐An , Liu Yi‐Hung , Peng Shie‐Ming , Liu Shiuh‐Tzung 
Published: February 2015

AbstractThe reaction of calcium naphthyridine‐2,7‐dicarboxylate (Cadcnp) with Ru2(OAc)4Cl in water resulted in the formation of Ca[Ru2(dcnp)(OAc)3]2 (3). X‐ray crystal structural analysis of 3 confirmed its molecular structure and showed that the calcium ion binds to the lateral carboxylate groups of four neighboring anionic units of [Ru2(dcnp)(μ‐OAc)3] and two acetone molecules to form a two‐dimensional framework. The RuII–RuII valence state of the diruthenium core was supported by superconducting quantum interference device (SQUID) magnetometry [μeff (300 K) = 2.77 μB]. Complex 3 appears to be an efficient catalyst for the oxidative cleavage of olefins in aqueous media under mild conditions. Typically, the reaction of pulegone with NaIO4 in water catalyzed by 3 (1 mol‐%) at 45 °C afforded 3‐methyladipic acid quantitatively.
Comparative study on volatile compounds, fatty acids, squalene and quality parameters from whole fruit, pulp and seed oils of two tunisian olive cultivars using chemometrics
Authors: Ben Mansour Amir , Flamini Guido , Ben Selma Zied , Le Dréau Yveline , Artaud Jacques , Abdelhedi Ridha , Bouaziz Mohamed 
Published: February 2015

The oils of olive fruits, pulps and seeds of two main Tunisian cultivars of olive trees (Chemlali and Oueslati) were extracted at two different indices of maturity. The free acidity, peroxide value, spectrophotometric indices, chlorophyll content, squalene, fatty acids, aroma, and sensory profiles of oils were analyzed. Fruit and pulp oils had similar fatty acid compositions. While, seed oils have fatty acid profiles that are different from both varieties. For the first time in this work, squalene content in the fruit, pulp, and seeds oils were measured by gas chromatography and it decreased during maturation. Its concentration in the seed oils were lower than those found in fruit and pulp oils. The volatile profiles of twelve Tunisian olive oils obtained from different parts of fruits were established by solid phase micro‐extraction (SPME) coupled with gas chromatography (GC) and gas chromatography‐mass spectrometry (GC‐MS). Sixty‐six compounds were identified and characterized, representing 92.4 and 97.6% of the total volatiles. Principal component analysis showed that olive oil quality is strongly affected by olive cultivar, maturity index and the different olive parts.Practical applications: Nowadays, extractions of olive oil processes require grinding of the whole olives. The proposed method is useful alternative process for olive oil production involves olive destoning before extraction of the oil. although destoning lowers olive oil yields, manufacturing plants for stone removal and milling of pulp have been recently set up, showing good oil yield. Interest in this technology is increasing, and some producers believe that oils obtained from destoned olives are of better quality than oils extracted from the whole fruit. Indeed, oils extracted from destoned olives had a better sensory property than oils obtained from the traditional milling of entire fruits and is very important from a marketing point of view for the olive oil company.The different parts of the olive (seeds, pulps and whole fruits) seem to play a very significant role for the qualitative characteristics and the sensory attributes of Chemlali and Oueslati olive oils. In addition, these results have proven that the cultivar and the olive parts influence the quali‐quantitative production of volatiles and consequently the final aroma of the oil.
Fatty acid composition, tocopherol, and sterol contents of sumac (Rhus coriaria L.) fruit oils
Authors: Matthaus Bertrand , Özcan Mehmet Musa 
Published: February 2015

The aim of this study is to establish oil content, fatty acid composition, tocopherol, and sterol contents of sumac fruits. The oil contents of sumac samples collected from different locations ranged from 7.7% (Hakkari) to 14.7% (Mut‐Mersin). Sumac oil contained a considerable amount of linoleic acid (56.60–61.56%). The total amount of tocopherols ranged from 65.20 mg/kg (Mersin‐Mut) to 126.37 mg/kg (Manisa). The highest α‐tocopherol content was in Mersin (Gülnar) fruits (4.64 mg/kg) and Gaziantep (4.22 mg/kg). The concentration of total sterols ranged from 2738.46 mg/kg (Siirt) to 7211.61 mg/kg (Kastamonu) in oils of all sumac fruits.The major fatty acids found in sumac oil were palmitic, oleic and linoleic acids. γ‐Tocopherol is the predominant component in sumac fruit oil, followed by γ‐tocotriol. The composition of sterols in sumac oil is dominated by β‐sitosterol, which accounted for about 75–80% of the total sterols in the oil.
Rheological properties, textural properties, and storage stability of palm kernel‐based diacylglycerol‐enriched mayonnaise
Authors: Phuah Eng‐Tong , Beh Boon‐Kee , Lim Cindy Shu‐Ying , Tang Teck‐Kim , Lee Yee‐Ying , Lai Oi‐Ming 
Published: February 2015

The effect of replacement of soybean oil (SBO) with 0, 5, 10, 15, and 20% palm kernel based‐diacylglycerol (PKDG) which were referred to as SD1000, SD9505, SD9010, SD8515, and SD8020 formulations, respectively, on the rheological properties, textural properties, and storage stability of mayonnaise were evaluated in this study. Emulsion stability results demonstrated no significant differences (P > 0.05) among all formulations except SD8020 which exhibited diminished emulsion stability. In terms of textural properties, both SD9010 and SD8020 showed closer textural characteristics compared with control. Microstructure evaluation of all mayonnaise formulations revealed significant increases in oil droplet diameter in tandem with increasing PKDG concentration. For rheological properties, all mayonnaise formulated displayed similar gel‐like behavior with greater storage modulus (G') than loss modulus (G”) and loss tangent (tan δ) less than 0.3. Results indicated that up to 10% PKDG was suitable to be incorporated in healthy mayonnaise formulation. Both SD9505 and SD9010 were subsequently evaluated for their stability throughout a 2‐month storage period. All mayonnaise displayed satisfying stability during storage with gradual increment in peroxide value, free fatty acid level, and G'G” crossover value except control. Additionally, an insignificant change in viscoelastic properties (P > 0.05) was observed after storage for all formulations examined.Practical applications: This present work has three main practical applications: (i) enable the incorporation of PKDG as a functional ingredient into a mayonnaise system; (ii) provide knowledge and understanding of the physicochemical, rheological, and textural properties of PKDG‐enriched mayonnaise; and (iii) give insight into the storage stability of PKDG‐incorporated mayonnaise throughout the 2‐month storage period.The purpose of this study was to produce mayonnaise using PKDG as a substitute for conventional soybean oil (SBO) in order to improve the nutritional properties of mayonnaise. Physicochemical and textural properties of PKDG‐enriched mayonnaise were evaluated and compared with conventional SBO without substitution. Four PKDG‐enriched mayonnaises were developed from both PKDG and SBO which were SD9505 (XSBO = 0.95, XPKDG = 0.05), SD9010 (XSBO = 0.90, XPKDG = 0.10), SD8515 (XSBO = 0.85, XPKDG = 0.15), and SD8020 (XSBO = 0.80, XPKDG = 0.20). Optimal formulations of PKDG‐enriched mayonnaises were further assessed for their storage stability at room temperature (20°C) for a period of 2 months.
Catalytic copolymerization of methyl 9,10‐epoxystearate and cyclic anhydrides under neat conditions
Authors: Biermann Ursula , Sehlinger Ansgar , Meier Michael A. R. , Metzger Jürgen O. 
Published: February 2015

The solvent‐free copolymerization of methyl 9,10‐epoxystearate 1 with different cyclic anhydrides, such as phthalic anhydride 2, succinic anhydride 3, maleic anhydride 4, or the Diels‐Alder‐adduct 5 of methyl α‐eleostearate and maleic anhydride, using a (salen)CrIIICl‐catalyst and n‐Bu4NCl as co‐catalyst is demonstrated. In this way, polyesters (Mn = 2000–10,000 g/mol) with low glass transition temperatures were formed. The reaction is characterized by sustainable aspects, for instance, the use of starting materials derived from renewable resources (>60%), low catalyst loadings, and no added solvent.Practical applicationsThe alternating ring‐opening copolymerization of epoxides such as methyl 9,10‐epoxystearate with various cyclic acid anhydrides such as phthalic anhydride and succinic anhydride, respectively, afford polyesters of narrow molecular weight distributions using a (salen)CrIIICl catalyst in the presence of n‐Bu4NCl. The pending long chain alkyl groups introduced in the polyesters by the fat derived substrates attribute amorphous properties to the polymers. Various fatty epoxides are easily available and open up the possibility for the synthesis of new highly branched polyestersPolyesters are formed by the copolymerization of methyl 9,10‐epoxystearate with different cyclic anhydrides using a (salen)CrIIICl‐catalyst in the presence of n‐Bu4NCl. The reaction is performed under neat conditions and the resulting alternating copolymers are featured by a high renewable content. In case of phthalic anhydride as co‐monomer, number average molecular weights of up to 10 kDa with narrow dispersities were obtained.
Hydrolysis of lysophosphatidylcholines by a lipase from Malassezia globosa
Authors: Wang Xuping , Xu Huan , Lan Dongming , Yang Bo , Wang Yonghua 
Published: February 2015

SMG1, a lipase produced by recombinant Pichia pastoris shows specific activity on mono‐ and diacylglycerol but not on triacylglycerol. To better understand the substrate selectivity of SMG1, the hydrolysis ability of SMG1 on PC and LPC were investigated. SMG1 was found to hydrolyze LPC, but has no activity toward PC. Besides, SMG1 lipase preferred 2‐LPC to 1‐LPC. Molecular docking simulation indicated that Phe278 and Leu103 contribute to reduce the size of the catalytic pocket, resulting in preventing PC access to the active site of SMG1. Our work may shed some light to understand the molecular basis of substrate selectivity of lipase with preference for DAGs.Practical applications: To our knowledge, there is no report on the application of lipases with preference for DAGs in phospholipids modification. This study could contribute to develop potential applications of SMG1 lipase in phospholipids industries.(A) Hydrolysis curve of 1‐LPC, 2‐LPC, and PC by SMG1(B) Modeled 3‐D structure of the SMG1‐2‐LPC complex(C) Modeled 3‐D structure of the SMG1‐1‐LPC complex(D) F278 prevents PC enter into catalytic pocket.
1,2‐Stereochemical Induction in the PdII‐Catalyzed Conjugate Addition of Boronic Acids
Authors: Roscales Silvia , Sánchez Francisco , Csákÿ Aurelio G. 
Published: February 2015

AbstractPalladium(II) catalysis has been used in the substrate‐controlled 1,2‐chiral induction of the conjugate addition of boronic acids to enantiopure α,β‐unsaturated ketones and esters without competition from the Mirozoki–Heck reaction. Bedford's palladacycle was found to control the stereoselectivity without the need for additional chiral ligands. We report that the PdII‐catalyzed conjugate addition reaction between boronic acids and acyclic ketones or esters that bear a hydroxyl substituent at their γ‐position (glyceraldehyde derivatives) can afford high levels of anti stereoselection, comparable to those reported previously using more expensive RhI catalysts. On the other hand, high levels of syn stereoselectivity were observed with acyclic esters that bear an amino substituent at their γ‐position (serine derivatives). In this case, the levels of stereoselection could be enhanced by using cyclic derivatives derived from Garner's aldehyde.
Ultrasound‐assisted transesterification of refined and crude palm oils using heterogeneous palm oil mill fly ash supported calcium oxide catalyst
Authors: Ho Wilson Wei Sheng , Ng Hoon Kiat , Gan Suyin , Chan Wai Loon 
Published: February 2015

AbstractUltrasound‐assisted transesterification of refined palm oil (RPO) and crude palm oil (CPO) to produce biodiesel using a palm oil mill fly ash supported calcium oxide (CaO) catalyst is studied in this work. The reaction time is significantly reduced from a maximum of 360 min under conventional mixing to just 30 min with the use of ultrasound. Under ultrasonic cavitation, the required catalyst loading and methanol to oil molar ratio to produce comparable yields and fatty acid methyl esters (FAME) conversions as conventional mixing are lower. For RPO, the ultrasound‐assisted transesterification conditions of 60% ultrasonic amplitude, 30 min reaction time, 4 wt.% catalyst loading, and 9:1 methanol to oil molar ratio result in maximum biodiesel yield and FAME conversion of 85.23% and 97.02%, respectively. As for CPO, maximum biodiesel yield of 73.23% and FAME conversion of 97.04% are obtained under the same conditions with the exception of a methanol to oil molar ratio of 12:1. Key physicochemical properties of the produced biodiesels are found to be within the limits set by EN 14214 and ASTM D 6751. Catalyst reusability tests indicate that the catalyst can be used up to three consecutive cycles after regeneration using methanol washing followed by recalcination at 850°C for 2 h.
Default‐mode network functional connectivity is closely related to metabolic activity
Authors: Passow Susanne , Specht Karsten , Adamsen Tom Christian , Biermann Martin , Brekke Njål , Craven Alexander Richard , Ersland Lars , Grüner Renate , Kleven‐Madsen Nina , Kvernenes Ole‐Heine , Schwarzlmüller Thomas , Olesen Rasmus Aamand , Hugdahl Kenneth 
Published: February 2015

AbstractOver the last decade, the brain's default‐mode network (DMN) and its function has attracted a lot of attention in the field of neuroscience. However, the exact underlying mechanisms of DMN functional connectivity, or more specifically, the blood‐oxygen level‐dependent (BOLD) signal, are still incompletely understood. In the present study, we combined 2‐deoxy‐2‐[18F]fluoroglucose positron emission tomography (FDG‐PET), proton magnetic resonance spectroscopy (1H‐MRS), and resting‐state functional magnetic resonance imaging (rs‐fMRI) to investigate more directly the association between local glucose consumption, local glutamatergic neurotransmission and DMN functional connectivity during rest. The results of the correlation analyzes using the dorsal posterior cingulate cortex (dPCC) as seed region showed spatial similarities between fluctuations in FDG‐uptake and fluctuations in BOLD signal. More specifically, in both modalities the same DMN areas in the inferior parietal lobe, angular gyrus, precuneus, middle, and medial frontal gyrus were positively correlated with the dPCC. Furthermore, we could demonstrate that local glucose consumption in the medial frontal gyrus, PCC and left angular gyrus was associated with functional connectivity within the DMN. We did not, however, find a relationship between glutamatergic neurotransmission and functional connectivity. In line with very recent findings, our results lend further support for a close association between local metabolic activity and functional connectivity and provide further insights towards a better understanding of the underlying mechanism of the BOLD signal. Hum Brain Mapp 36:2027–2038, 2015. © 2015 Wiley Periodicals, Inc.
The diffeomorphometry of regional shape change rates and its relevance to cognitive deterioration in mild cognitive impairment and Alzheimer's disease
Authors: Tang Xiaoying , Holland Dominic , Dale Anders M. , Younes Laurent , Miller Michael I. ,   for the Alzheimer's Disease Neuroimaging Initiative
Published: February 2015

AbstractWe proposed a diffeomorphometry‐based statistical pipeline to study the regional shape change rates of the bilateral hippocampus, amygdala, and ventricle in mild cognitive impairment (MCI) and Alzheimer's disease (AD) compared with healthy controls (HC), using sequential magnetic resonance imaging (MRI) scans of 713 subjects (3,123 scans in total). The subgroup shape atrophy rates of the bilateral hippocampus and amygdala, as well as the expansion rates of the bilateral ventricles, for a majority of vertices were found to follow the order of
. The bilateral hippocampus and the left amygdala were subsegmented into multiple functionally meaningful subregions with the help of high‐field MRI scans. The largest group differences in localized shape atrophy rates on the hippocampus were found to occur in CA1, followed by subiculum, CA2, and finally CA3/dentate gyrus, which is consistent with the neurofibrillary tangle accumulation trajectory. Highly nonuniform group differences were detected on the amygdala; vertices on the core amygdala (basolateral and lateral nucleus) revealed much larger atrophy rates, whereas those on the noncore amygdala (mainly centromedial) displayed similar or even smaller atrophy rates in AD relative to HC. The temporal horns of the ventricles were observed to have the largest localized ventricular expansion rate differences; with the AD group showing larger localized expansion rates on the anterior horn and the body part of the ventricles as well. Significant correlations were observed between the localized shape change rates of each of these six structures and the cognitive deterioration rates as quantified by the Alzheimer's Disease Assessment Scale‐Cognitive Behavior Section increase rate and the Mini Mental State Examination decrease rate. Hum Brain Mapp 36:2093–2117, 2015. © 2015 Wiley Periodicals, Inc.
Minor allele frequency of myeloproliferative neoplasm mutations in the Irish blood donor population
Authors: Titmarsh Glen J. , McKay Gareth J. , Lawler Mark , Anderson Lesley A. , McMullin Mary Frances 
Published: February 2015

AbstractMyeloproliferative neoplasms (MPNs) are rare diseases that include classic entities; polycythaemia vera, essential thrombocythaemia and primary myelofibrosis. In this short report, minor allele frequencies of common MPN mutations are compared between the Irish blood donor population and other populations of European descent using data from the Haplotype Map project. The Affymetrix array 6.0 platform was utilised identifying nine single nucleotide polymorphisms (SNPs) and six proxy SNPs. The variability of allele frequencies for MPN mutations could account for the different incidence rates seen between populations of European ancestry, giving a better understanding of the genetic predisposition to MPNs. Copyright © 2015 John Wiley & Sons, Ltd.
Different cytotoxicity responses to antimicrobial nanosilver coatings when comparing extract‐based and direct‐contact assays
Authors: Sussman Eric M. , Casey Brendan J. , Dutta Debargh , Dair Benita J. 
Published: February 2015

AbstractThis study was performed to understand how the choice of cytotoxicity assay format affects the observed biocompatibility of nanosilver (nAg). nAg coatings are physical coatings containing silver (Ag) that have feature sizes of 100 nm or less, often in the form of nanoparticles or grains. They are used on medical devices to prevent infection, but in spite of this intended benefit, observations of potential cytotoxicity from nAg have been reported in numerous published studies. For medical device regulation, cytotoxicity testing is part of a biocompatibility evaluation, in which specific test methods are chosen based on the technological characteristics and intended use of a device. For this study, nAg‐coated tissue culture polystyrene surfaces were prepared using magnetron sputter coating, resulting in nAg films of 0.2 to 311 µg cm−2 Ag. These coatings exhibited nanometer‐scale morphologies and demonstrated a > 4log10 reduction in Escherichia coli viability. It was observed that extracts of nAg caused no cytotoxicity to L929 mouse fibroblasts, but cells cultured directly on nAg coatings (direct‐contact assay format) showed a dose‐dependent reduction in viability by up to 100% (P < 0.001). Results using inductively coupled plasma mass spectrometry to measure Ag release suggested that extracts of nAg are not toxic because the dissolved Ag in those samples becomes less cytotoxic over time, probably owing to the reaction with cell culture media and serum (six‐fold cytotoxicity reductions observed over a 24‐h period). These findings highlight the potential value of direct‐contact cytotoxicity testing for nAg in predicting biological interactions with cells or tissue in vivo. Published 2014. This article is a U.S. Government work and is in the public domain in the USA.
Photobleaching and phototoxicity of KillerRed in tumor spheroids induced by continuous wave and pulsed laser illumination
Authors: Kuznetsova Daria S. , Shirmanova Marina V. , Dudenkova Varvara V. , Subochev Pavel V. , Turchin Ilya V. , Zagaynova Elena V. , Lukyanov Sergey A. , Shakhov Boris E. , Kamensky Vladislav A. 
Published: February 2015

The purpose of this study was to evaluate photobleaching of the genetically encoded photosensitizer KillerRed in tumor spheroids upon pulsed and continuous wave (CW) laser irradiation and to analyze the mechanisms of cancer cell death after the treatment. We observed the light‐dose dependent mechanism of KillerRed photobleaching over a wide range of fluence rates. Loss of fluorescence was limited to 80% at light doses of 150 J/cm2 and more. Based on the bleaching curves, six PDT regimes were applied for irradiation using CW and pulsed regimes at a power density of 160 mW/cm2 and light doses of 140 J/cm2, 170 J/cm2 and 200 J/cm2. Irradiation of KillerRed‐expressing spheroids in the pulsed mode (pulse duration 15 ns, pulse repetition rate 10 Hz) induced predominantly apoptotic cell death, while in the case of CW mode the cancer cells underwent necrosis. In general, these results improve our understanding of photobleaching mechanisms in GFP‐like proteins and show the importance of appropriate selection of treatment mode for PDT with KillerRed.
Representative fluorescence image of two KillerRed‐expressing spheroids before and immediately after CW irradiation.magnified imageRepresentative fluorescence image of two KillerRed‐expressing spheroids before and immediately after CW irradiation.