bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cancer incidence, morbidity, and survival in Canadian first nation children: A Manitoba population‐based study from the cancer in young people in Canada (CYP‐C) registry
Authors: Stammers David M. , Israels Sara J. , Lambert Pascal J. , Cuvelier Geoff D.E. 
Published: February 2014

AbstractBackgroundHealth disparities between Canadian First Nation (FN) people and the rest of the national population exist. No studies have specifically documented cancer‐related health outcomes in Canadian FN children. The purpose of this study was to describe the incidence of pediatric malignancies in Manitoba FN children, and to compare morbidity patterns and survival between FN and non‐FN children with cancer in the Canadian province of Manitoba.ProcedureA retrospective, population‐based review of all children (0–14.99 years) diagnosed with malignancy (2001–2008) in Manitoba, Canada was undertaken using the Cancer in Young People in Canada registry. FN children were compared to the non‐FN population for markers of morbidity and survival.ResultsThe average annual age‐standardized incidence rate for all childhood cancers in FN children was 132 per 1,000,000 per year. 240 children were included in the morbidity and survival analyses (38 FN; 202 non‐FN). No differences were found between FN and non‐FN children in time from first presentation of symptoms to consultation with an oncology specialist or diagnosis, or number of hospital admissions / total days of admission for treatment complications. Overall survival was inferior for FN children in univariable analysis (P = 0.048) but not when risk group was included in a multivariable analysis (P = 0.15). No difference in event free survival or cumulative incidence of relapse was identified.ConclusionThe estimated incidence of childhood cancers in the Manitoba FN population is similar to provincial incidence rates. No differences in morbidity patterns or survival were found between Manitoba FN and non‐FN children with cancer. Pediatr Blood Cancer 2014;61:2164–2169. © 2014 Wiley Periodicals, Inc.
Saturated low‐temperature conductivity in ultrafast semiconductor nanocomposites
Authors: Zhang W. , Martin M. , Brown E. R. 
Published: February 2014

AbstractThis Letter presents studies on low‐field electrical conduction in the range of 4–300 K for an ultrafast material, i.e., InGaAs:ErAs grown by molecular beam epitaxy. The unique properties include nano‐scale ErAs crystallites in the host semiconductor InGaAs, a deep Fermi level and picosecond ultrafast photocarrier recombination. As the temperature drops, the conduction mechanisms are in the sequence of: thermal activation, nearest‐neighbor hopping, and variable‐range hopping. In the low‐temperature limit, finite‐con‐ductivity metallic behavior, not insulating, was observed. This unusual conduction behavior, related to the nanometer‐scale ErAs crystallite islands, is explained with the Abrahams scaling theory.magnified imageCurrent vs. temperature for (A) InGaAs:ErAs – the ultrafast nanocomposite; and (C) an undoped InGaAs.(© 2014 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
S‐MIM field trials results
Authors: Hermenier Romain , Del Bianco Alessandro , Marchitti Maria‐Antonietta , Heyn Thomas , Recchia Annamaria , Collard Florian , Andrenacci Marco , Mendola Gaeteno , Vaccaro Attilio 
Published: February 2014

SUMMARYAn intelligent transport system open platform integrating the S‐band Mobile Interactive Multimedia messaging return channel protocol over satellite (based on Enhanced Spread Spectrum Aloha) has been developed and tested under real environment conditions within the framework of SafeTRIP, an FP7 EU‐funded project. This paper presents the first field trials results using the S‐band Mobile Interactive Multimedia technology. The introduced forward and return link outcomes have been derived from mobile field trials carried out in the surroundings of the German Aerospace Center (DLR) in Germany. Finally the validation of the system performances has been realized thanks to the use of a traffic emulator that can simulate a large population of Enhanced Spread Spectrum Aloha terminals. Copyright © 2014 John Wiley & Sons, Ltd.
Reliable space‐to‐Earth communication as a secondary service in the 460–470 MHz band
Authors: Gunther Jacob , Fish Chad , Swenson Charles , Moon Todd 
Published: February 2014

SummaryBy regulatory fiat, secondary communication services cannot cause harmful interference to primary communication services, and they cannot claim protection from harmful interference from the primary service. This paper is about establishing reliable high data rate space‐to‐Earth communication in the asymmetric setting of a secondary service in the 460–470 MHz frequency band. In this band, the primary services consist of signals that are narrowband relative to the bandwidth of the signal of interest. A frequency domain approach is adopted to detect and cancel narrowband interference. After this processing, the signal of interest can be demodulated by standard techniques. This approach is shown to be effective on real data collected for the Dynamic Ionosphere CubeSat Experiment mission. The telemetry concept for Dynamic Ionosphere CubeSat Experiment was developed with a view toward demonstrating a high‐speed data downlink capability that may be adopted as a standard for future CubeSat missions. Copyright © 2014 John Wiley & Sons, Ltd.
Dose‐dependent effects of metals on gene expression in the sydney rock oyster, Saccostrea glomerata
Authors: Taylor Daisy A. , Nair Sham V. , Thompson Emma L. , Raftos David A. 
Published: February 2014

ABSTRACTIn the current study, we tested the effects of common environmental contaminants (the metals zinc and lead) on gene expression in Sydney rock oysters (Saccrostrea glomerata). Oysters were exposed to a range of metal concentrations under controlled laboratory conditions. The expression of 14 putative stress response genes was then measured using quantitative, real‐time (q) PCR. The expression of all 14 genes was significantly affected (p < 0.05 vs. nonexposed controls) by at least one of the metals, and by at least one dose of metal. For 5 of the 14 target genes (actin, calmodulin, superoxide dismutase, topoisomerase I, and tubulin) the alteration of expression relative to controls was highest at intermediate (rather than high) doses of metals. Such responses may reflect adaptive (acclimation) reactions in gene expression at low to intermediate doses of contaminants, followed by a decline in expression resulting from exposure at higher doses. The data are discussed in terms of the intracellular pathways affected by metal contamination, and the relevance of such gene expression data to environmental biomonitoring. © 2014 Wiley Periodicals, Inc. Environ Toxicol 30: 989–998, 2015.
Vertex nomination
Authors: Coppersmith Glen 
Published: February 2014

Vertex nomination is a subclass of recommender systems operating on attributed graphs. Attributed graphs are an attractive way to represent data from a diverse set of natural and manmade phenomena. Frequently, these data have latent attributes or class memberships that are of interest and uncovering them is of some intrinsic value. So‐called recommender systems address the ‘more like this’ problem: given a subset of the data labeled as ‘interesting’, find unlabeled examples that are ‘similarly interesting’, often with the assumption that they are from the same latent class or possess similar latent attributes. Unsurprisingly, recommender systems operating on attributed graphs have generated an interesting body of research, detailing both theoretical and practical advances for a range of applications. This advanced review examines the relevant literature, particularly focused on the importance and inclusion of edge‐ and vertex attributes, used in conjunction with the graph structure. We include example applications from human language technology, biology, and neuroscience for concreteness, although the algorithms discussed are widely applicable. WIREs Comput Stat 2014, 6:144–153. doi: 10.1002/wics.1294This article is categorized under:

Algorithms and Computational Methods > Quadratic and Nonlinear Programming
Charge and color breaking constraints in MSSM after the Higgs discovery at LHC
Authors: Chowdhury Debtosh , Godbole Rohini M. , Mohan Kirtimaan A. , Vempati Sudhir K. 
Published: February 2014

Abstract
We revisit the constraints on the parameter space of the Minimal Supersymmetric Standard Model (MSSM), from charge and color breaking minima in the light of information on the Higgs from the LHC so far. We study the behavior of the scalar potential keeping two light sfermion fields along with the Higgs in the pMSSM framework and analyze the stability of the vacuum. We find that for lightest stops ≲ 1 TeV and small μ ≲ 500 GeV, the absolute stability of the potential can be attained only for $ \left| {{X_t}} \right|\lesssim \sqrt{{6{m_{{\widetilde{t}1}}}{m_{{\widetilde{t}2}}}}} $. The bounds become stronger for larger values of the μ parameter. Note that this is approximately the value of Xt which maximizes the Higgs mass. Our bounds on the low scale MSSM parameters are more stringent than those reported earlier in literature. We reanalyze the stau sector as well, keeping both staus. We study the connections between the observed Higgs rates and vacuum (meta)stability. We show how a precision study of the ratio of signal strengths, (μ
γγ
/μ
ZZ
) can shed further light.
An Assessment of Time Involved in Pre‐test Case Review and Counseling for a Whole Genome Sequencing Clinical Research Program
Authors: Williams Janet L. , Faucett W. Andrew , Smith‐Packard Bethanny , Wagner Monisa , Williams Marc S. 
Published: February 2014

AbstractWhole genome sequencing (WGS) is being used for evaluation of individuals with undiagnosed disease of suspected genetic origin. Implementing WGS into clinical practice will place an increased burden upon care teams with regard to pre‐test patient education and counseling about results. To quantitate the time needed for appropriate pre‐test evaluation of participants in WGS testing, we documented the time spent by our clinical research group on various activities related to program preparation, participant screening, and consent prior to WGS. Participants were children or young adults with autism, intellectual or developmental disability, and/or congenital anomalies, who have remained undiagnosed despite previous evaluation, and their biologic parents. Results showed that significant time was spent in securing allocation of clinical research space to counsel participants and families, and in acquisition and review of participant's medical records. Pre‐enrollment chart review identified two individuals with existing diagnoses resulting in savings of $30,000 for the genome sequencing alone, as well as saving hours of personnel time for genome interpretation and communication of WGS results. New WGS programs should plan for costs associated with additional pre‐test administrative planning and patient evaluation time that will be required to provide high quality care.
Resonant motions in the presence of degeneracies for quasi-periodically perturbed systems
Authors: CORSI LIVIA , GENTILE GUIDO 
Published: February 2014

AbstractWe consider one-dimensional systems in the presence of a quasi-periodic perturbation, in the analytical setting, and study the problem of existence of quasi-periodic solutions which are resonant with the frequency vector of the perturbation. We assume that the unperturbed system is locally integrable and anisochronous, and that the frequency vector of the perturbation satisfies the Bryuno condition. Existence of resonant solutions is related to the zeros of a suitable function, called the Melnikov function—by analogy with the periodic case. We show that, if the Melnikov function has a zero of odd order and under some further condition on the sign of the perturbation parameter, then there exists at least one resonant solution which continues an unperturbed solution. If the Melnikov function is identically zero then one can push perturbation theory up to the order where a counterpart of Melnikov function appears and does not vanish identically: if such a function has a zero of odd order and a suitable positiveness condition is met, again the same persistence result is obtained. If the system is Hamiltonian, then the procedure can be indefinitely iterated and no positiveness condition must be required: as a byproduct, the result follows that at least one resonant quasi-periodic solution always exists with no assumption on the perturbation. Such a solution can be interpreted as a (parabolic) lower-dimensional torus.
The Pesin entropy formula for diffeomorphisms with dominated splitting
Authors: CATSIGERAS ELEONORA , CERMINARA MARCELO , ENRICH HEBER 
Published: February 2014

AbstractFor any$C^1$diffeomorphism with dominated splitting, we consider a non-empty set of invariant measures that describes the asymptotic statistics of Lebesgue-almost all orbits. They are the limits of convergent subsequences of averages of the Dirac delta measures supported on those orbits. We prove that the metric entropy of each of these measures is bounded from below by the sum of the Lyapunov exponents on the dominating sub-bundle. As a consequence, if those exponents are non-negative, and if the exponents on the dominated sub-bundle are non-positive, those measures satisfy the Pesin entropy formula.
Modeling potential as fiber entropy and pressure as entropy
Authors: DOWNAROWICZ TOMASZ , ZHANG GUO HUA 
Published: February 2014

AbstractWe first prove that topological fiber entropy potential in a relatively symbolic extension (topological joining with a subshift) of a topological dynamical system (which is a non-negative, non-decreasing, upper semicontinuous and subadditive potential$\mathfrak{H}$) yields topological pressure equal to the topological entropy of the extended system. The terms occurring on the other side of the variational principle for pressure are equal to the extension entropies of the invariant measures. Thus the variational principle for pressure reduces to the usual variational principle (for entropy) applied to the extended system. Next we prove our main theorem saying that every non-negative, upper semicontinuous and subadditive potential$\mathfrak{F}$(we drop the monotonicity assumption) is ‘nearly equal’ to the fiber entropy potentialHin some relatively symbolic extension of the system, in the sense that all terms occurring in the variational principle for pressure are the same for both potentials. This gives a new interpretation of all such potentials$\mathfrak{F}$as a kind of additional information function enhancing the natural information arising from the dynamical system, and provides a new proof of the variational principle for pressure. At the end of the paper we provide examples showing that both assumptions, continuity and additivity, under which so-called lower pressure (defined with the help of spanning sets) equals the pressure, are essential, already in the class of non-negative, upper semicontinuous, subadditive potentials.
On rationally ergodic and rationally weakly mixing rank-one transformations
Authors: DAI IRVING , GARCIA XAVIER , PĂDURARIU TUDOR , SILVA CESAR E. 
Published: February 2014

AbstractWe study the notions of weak rational ergodicity and rational weak mixing as defined by J. Aaronson [Rational ergodicity and a metric invariant for Markov shifts.Israel J. Math. 27(2) (1977), 93–123; Rational weak mixing in infinite measure spaces.Ergod. Th. & Dynam. Sys.2012, to appear.http://arxiv.org/abs/1105.3541]. We prove that various families of infinite measure-preserving rank-one transformations possess or do not posses these properties, and consider their relation to other notions of mixing in infinite measure.
A Pilot Study to Investigate the Efficacy of Nicotine Oral Soluble Film, Lozenge and Gum in Relief of Acute Smoking Cue-provoked Craving for Cigarette in Low Dependence Smokers
Authors: Du Daniel , Borders James , Selmani Alex , Waverczak William 
Published: February 2014

Introduction: A new nicotine film that releases nicotine quickly may lead to faster craving relief.Aims: This study compares the efficacy of 2.5 mg nicotine film with 2 mg nicotine lozenge and 2 mg nicotine gum on relieving provoked craving in low dependence smokers.Methods: A randomised, open-label, active comparators controlled study was conducted in 120 subjects. Subjects were abstinent from smoking for 4 hours prior to being provoked with smoking cues. After post-provocation craving assessment, subjects were administered one dose of the 3 treatments: nicotine film, lozenge, or gum. Craving intensity was then assessed at 50 seconds, 3, 5, 7, 15, 20, 25 and 30 minutes after administration.Results/Findings: Three treatments reduced craving with similar maximum effects. The effect was maintained up to 30 minutes. Nicotine film significantly reduced more craving than lozenge at 50 seconds, 3 and 5 minutes. It also significantly reduced more craving than gum at 50 seconds and 3 minutes. There was no significant difference between lozenge and gum.Conclusions: Nicotine film, lozenge and gum have similar maximum craving relief. Nicotine film significantly reduced more craving than lozenge and gum at early time points. Nicotine film may be particularly useful to provide acute craving relief.
Association between theNOTCH4gene rs3131296 polymorphism with schizophrenia risk in the Chinese Zhuang population and Chinese Han population
Authors: Su Li , Long Jianxiong , Liang Baoyun , Gu Lian , Pan Runde , Li Liushan , Zhou Yang , Tang Xianyan , Jiang Junjun , Chen Qiang , Wei Bo 
Published: February 2014

BackgroundSchizophrenia (SZ) is a common severe psychiatric disorder and a complex polygenic inherited disease that has not yet been fully interpreted. Heredity was proven to play an important role in the development of SZ. The association between theNOTCH4gene rs3131296 polymorphism and SZ was reported to reach significance at the genome-wide level; therefore, it is necessary to replicate this association in other different populations.MethodsTo evaluate the association of theNOTCH4gene rs3131296 polymorphism with the risk for SZ, and to explore whether a significant association could be replicated in different ethnic groups of China, we conducted this case–control study on 282 SZ cases (188 Han and 94 Zhuang) and 282 controls (188 Han and 94 Zhuang) among the Chinese Zhuang and Han populations.ResultsThe results showed no statistically significant difference in the genotype or allele frequencies of theNOTCH4gene variant rs3131296 between SZ patients and healthy controls in either the Zhuang or Han samples (p> 0.05). In addition, no significant difference was found in genotype or allele frequencies of theNOTCH4gene variant rs3131296 between cases and controls in the combined samples including Zhuang and Han samples.ConclusionsOur study failed to replicate the significant association between theNOTCH4gene rs3131296 polymorphism and the risk for SZ.
Review of flanking structures in meso- and micro-scales
Authors: MUKHERJEE SOUMYAJIT 
Published: February 2014

AbstractA variety of host-fabric elements (HE) cut by cross-cutting elements (CE) in rocks defines flanking structures (FS) on mesoscopic and microscopic scales. There has been renewed interest in studying and classifying the FS for their morphologies, useful as shear sense indicators and geneses. Existing non-genetic morphologic parameters for the FS are reviewed, and two new classification schemes are presented. One of these is based on the nature of the CE and whether HE penetrates it. The other scheme takes account of all the potential combinations of drag/no drag and slip/no slip of the HE. Deciphering the shear sense of the rock body from FS is complicated because the angular relationship between the CE and the primary shear planes might be opposite to what is found between S- and C- ductile shear fabrics. Further, single CEs can curve and several similar FS occur in reverse forms. As with mineral fish, the shape asymmetries of microscopic CEs indicate the shear sense. Conjugate FS (with non-parallel CEs) with interfering perturbation fields around the CEs are more reliable shear-sense indicators than FS with single CE. During low but increasing bulk strains, FS may evolve from one type to another, e.g. from a- to s-type. At high strain, FS can resemble intrafolial or sheath fold. Whether the drag is normal or reverse depends fundamentally on the initial angle between the HE and the CE and the relative magnitudes of throw and vertical separation.
Rohdella amazonica n. sp. (Aspidogastrea: Aspidogastridae) from the Amazoninan banded puffer fish Colomesus psittacus (Bloch & Schneider, 1801)
Authors: Giese E.G. , Silva M.V.O. , Videira M.N. , Furtado A.P. , Matos E.R. , Gonçalves E.C. , Melo F.T.V. , Santos J.N. 
Published: February 2014

AbstractAspidogastreans are commonly found infecting freshwater and marine molluscs, teleosts fishes and freshwater turtles. The subclass comprises four families – Rugogastridae Schell 1973, Stichocotylidae Faust & Tang 1936, Multicalycidae Gibson & Chinabut 1984 and Aspidogastridae Poche 1907 – and it is characterized by the presence of a ventral adhesive disc divided into rows of alveoli. In the current work, using light and scanning electron microscopy and molecular approaches, a new species of Aspidogastridae of the genus Rohdella Gibson & Chinabut, 1984, is described as a parasite of Colomesus psittacus in Brazil. The new taxon is distinguishable by the presence of oesophageal glands, teguments covered by ciliated papillae, and the position and shape of the hermaphroditic duct. The present work describes the third species of the genus Rohdella, thereby adding new morphological and molecular data regarding Aspidogastridae.
Phenotypic plasticity of maleSchistosoma mansonifrom the peritoneal cavity and hepatic portal system of laboratory mice and hamsters
Authors: Mati V.L.T , Freitas R.M. , Bicalho R.S. , Melo A.L. 
Published: February 2014

AbstractMorphometric analysis ofSchistosoma mansonimale worms obtained from AKR/J and Swiss mice was carried out. Rodents infected by the intraperitoneal route with 80 cercariae of the schistosome (LE strain) were killed by cervical dislocation at 45 and 60 days post-infection and both peritoneal lavage and perfusion of the portal system were performed for the recovery of adult worms. Characteristics including total body length, the distance between oral and ventral suckers, extension of testicular mass and the number of testes were considered in the morphological analysis. Changes that occurred inS. mansonirecovered from the peritoneal cavity or from the portal system of AKR/J and Swiss mice included total body length and reproductive characteristics. Significant morphometric alterations were also observed when worms recovered from the portal system of both strains of mice were compared with the schistosomes obtained from hamsters (Mesocricetus auratus), the vertebrate host in which the LE strain had been adapted and maintained by successive passages for more than four decades. The present results reinforce the idea thatS. mansonihas high plastic potential and adaptive capacity.