bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multivariate analysis of oral mucosal ulcers during orthodontic treatment
Authors: Chang Jing , Li Xue 
Published: July 2024

BACKGROUND
Orthodontic treatment can easily cause local soft tissue reactions in the oral cavity of patients under mechanical stress, leading to oral mucosal ulcers and affecting their quality of life. At present, only limited literature has explored the factors leading to oral ulcers in orthodontic treatment, and these research results are still controversial.
AIM
To investigate the current status and related factors of oral mucosal ulcers during orthodontic treatment, aiming to provide a valuable reference for preventing this disease in clinical practice.
METHODS
A total of 587 patients who underwent orthodontic treatment at the Peking University School of Stomatology and Hospital of Stomatology between 2020 and 2022 were selected and allocated to an observation or control group according to the incidence of oral mucosal ulcers during orthodontic therapy. A questionnaire survey was constructed to collect patient data, including basic information, lifestyle and eating habits, treatment details, mental factors, and trace element levels, and a comparative analysis of this data was performed between the two groups.
RESULTS
A logistic regression model with oral ulcers as the dependent variable was established. The regression results showed that age (≥ 60 years: odds ratio [OR]: 6.820; 95% confidence interval [CI]: 2.226–20.893), smoking history (smoking: OR: 4.434; 95%CI: 2.527–7.782), toothbrush hardness (hard: OR: 2.804; 95%CI: 1.746–4.505), dietary temperature (hot diet: OR: 1.399; 95%CI: 1.220–1.722), treatment course (> 1 year: OR: 3.830; 95%CI: 2.203–6.659), and tooth brushing frequency (> 1 time per day: OR: 0.228; 95%CI: 0.138–0.377) were independent factors for oral mucosal ulcers (P < 0.05). Furthermore, Zn level (OR: 0.945; 95%CI: 0.927–0.964) was a protective factor against oral ulcers, while the SAS (OR: 1.284; 95%CI: 1.197–1.378) and SDS (OR: 1.322; 95%CI: 1.231–1.419) scores were risk factors.
CONCLUSION
Age ≥ 60 years, smoking history, hard toothbrush, hot diet, treatment course for > 1 year, tooth brushing frequency of ≤ 1 time per day, and mental anxiety are independent risk factors for oral mucosal ulcers. Therefore, these factors should receive clinical attention and be incorporated into the development and optimization of preventive strategies for reducing oral ulcer incidence.
Study of the intensive care unit activity scale in the early rehabilitation of patients after direct cardiac surgery
Authors: Wang Li , Lu Jing-Ya , Ma Xiao-Xiao , Ma Lan-Ou 
Published: July 2024

BACKGROUND
Direct cardiac surgery often necessitates intensive post-operative care, and the intensive care unit (ICU) activity scale represents a crucial metric in assessing and guiding early rehabilitation efforts to enhance patient recovery.
AIM
To clarify the clinical application value of the ICU activity scale in the early recovery of patients after cardiac surgery.
METHODS
One hundred and twenty patients who underwent cardiac surgery between September 2020 and October 2021 were selected and divided into two groups using the random number table method. The observation group was rated using the ICU activity scale and the corresponding graded rehabilitation interventions were conducted based on the ICU activity scale. The control group was assessed in accordance with the routine rehabilitation activities, and the postoperative rehabilitation indexes of the patients in both groups were compared (time of tracheal intubation, time of ICU admission, occurrence of complications, and activity scores before ICU transfer). The two groups were compared according to postoperative rehabilitation indicators (time of tracheal intubation, length of ICU stay, and occurrence of complications) and activity scores before ICU transfer.
RESULTS
In the observation group, tracheal intubation time lasted for 18.30 ± 3.28 h and ICU admission time was 4.04 ± 0.83 d, which were significantly shorter than the control group (t -values: 2.97 and 2.038, respectively, P < 0.05). The observation group also had a significantly lower number of complications and adverse events compared to the control group (P < 0.05). Before ICU transfer, the observation group (6.7%) had few complications and adverse events than the control group (30.0 %), and this difference was statistically significant (P < 0.05). Additionally, the activity score was significantly higher in the observation (26.89 ± 0.97) compared to the control groups (22.63 ± 1.12 points) (t -value; -17.83, P < 0.05).
CONCLUSION
Implementation of early goal-directed activities in patients who underwent cardiac surgery using the ICU activity scale can promote the recovery of cardiac function.
Extragastrointestinal stromal tumors with diffuse membranous distribution with bleeding: A case report
Authors: Xu Jian-Duo , Wang Zheng , Zhou Qian , Meng Ning , Zhang Shu-Mei , Liu Nan 
Published: July 2024

BACKGROUND
Extragastrointestinal stromal tumors (EGIST) and gastrointestinal stromal tumors are of similar pathological type and form. Here we report a rare case of EGIST diffusely distributed in membranous tissue in abdominal cavity, the feature of which included diffuse tumors at membranous tissue in entire abdominal cavity and spontaneous bleeding of the tumors.
CASE SUMMARY
The patient was a 71-year man and hospitalized due to continuous pain at lower abdomen for more than 10 days. Upon physical examination, the patient had flat and tough abdomen with mild pressing pain at lower abdomen, no obvious abdominal mass was touchable, and shifting dullness was positive. Positron emission tomography-computed tomography (CT) showed that in his peritoneal cavity, there were multiple nodules of various sizes, seroperitoneum, multiple enlarged lymph nodes in abdominal/pelvic cavity and right external ilium as well as pulmonary nodules. Plain CT scanning at epigastrium/hypogastrium/pelvic cavity + enhanced three-dimensional reconstruction revealed multiple soft tissue nodules in abdominal/pelvic cavity, peritoneum and right groin. Tumor marker of carbohydrate antigen 125 was 808 U/mL, diffuse tuberous tumor was seen in abdominal/pelvic cavity during operation with hematocelia, and postoperative pathological examination confirmed EGIST. Imatinib was administered with better therapeutic effect.
CONCLUSION
Gene testing showed breast cancer susceptibility gene 1 interacting protein C-terminal helicase 1 and KIT genovariation, and the patient was treated with imatinib follow-up visit found that his clinical symptoms disappeared and the tumor load alleviated obviously via imageological examination.
Who seeks care after intimate partner violence in Cameroon? sociodemographic differences between a hospital and population sample of women
Authors: Yost Mark T. , Blair Kevin J. , Poppens McKayla , Mallahi Michelle , Dang Lauren Eyler , Oke Rasheedat , Carvalho Melissa , Etoundi-Mballa Georges Alain , Hubbard Alan , Kouo Ngamby Marquise , Maqungo Sithombo , Chironga Kudzai , McCoy Sandra I. , Chichom-Mefire Alain , Juillard Catherine , Maswime Salome , Dissak Delon Fanny Nadia 
Published: July 2024

Introduction
Little is known regarding health care seeking behaviors of women in sub-Saharan Africa, specifically Cameroon, who experience violence. The proportion of women who experienced violence enrolled in the Cameroon Trauma Registry (CTR) is lower than expected.

Methods
We concatenated the databases from the October 2017-December 2020 CTR and 2018 Cameroon Demographic and Health Survey (DHS) into a singular database for cross-sectional study. Continuous and categorical variables were compared with Wilcoxon rank-sum and Fisher’s exact test. Multivariable logistic regression examined associations between demographic factors and women belonging to the DHS or CTR cohort. We performed additional classification tree and random forest variable importance analyses.

Results
276 women (13%) in the CTR and 197 (13.1%) of women in the DHS endorsed violence from any perpetrator. A larger percentage of women in the DHS reported violence from an intimate partner (71.6% vs. 42.7%, p<0.001). CTR women who experienced IPV demonstrated greater university-level education (13.6% vs. 5.0%, p<0.001) and use of liquid petroleum gas (LPG) cooking fuel (64.4% vs. 41.1%, p<0.001). DHS women who experienced IPV reported greater ownership of agricultural land (29.8% vs. 9.3%, p<0.001). On regression, women who experienced IPV using LPG cooking fuel (aOR 2.55, p = 0.002) had greater odds of belonging to the CTR cohort while women who owned agricultural land (aOR 0.34, p = 0.007) had lower odds of presenting to hospital care. Classification tree variable observation demonstrated that LPG cooking fuel predicted a CTR woman who experienced IPV while ownership of agricultural land predicted a DHS woman who experienced IPV.

Conclusion
Women who experienced violence presenting for hospital care have characteristics associated with higher SES and are less likely to demonstrate factors associated with residence in a rural setting compared to the general population of women experiencing violence.
Roll-out of an educational workshop to improve knowledge and self-confidence of healthcare professionals engaged in mainstreaming of breast cancer genetics
Authors: Jenkins Valerie , Habibi Ruth , Hall Virginia , Leonard Pauline , Lawn Anneliese , Naik Jay , Papps-Williams Rachel , Fallowfield Lesley 
Published: July 2024

Background
There are calls worldwide for the mainstreaming of genetic testing in breast cancer (BC) clinics, but health care professionals (HCPs) are not always familiar with nor confident about genetic counselling. TRUSTING (Talking about Risk & uncertainties of Testing in Genetics is an educational programme shown to significantly improve HCPs’ knowledge, communication, self-confidence, and self-awareness. We rolled out TRUSTING workshops across the UK and probed their influence on mainstreaming within BC clinics.

Methods
1 surgeon, 3 oncologists, and 1 nurse specialist who had attended the original TRUSTING evaluation project were trained to facilitate the 8-hour programme in pairs. The participants (all health care professionals) attending their workshops completed 3 questionnaires: - 1) the Intolerance to Uncertainty Scale, 2) an 18-item multiple choice knowledge questionnaire about BRCA 1/2 gene testing, incidence and risk reducing interventions and 3) a 10-item questionnaire exploring self-confidence when advising patients and their families about these issues. Both knowledge and self-confidence were re-tested post workshop together with evaluation of the facilitators’ approach and overall satisfaction with the event. Follow-up questionnaires 3–12 months later examined impact of workshops on HCPs’ own practice and how mainstreaming was working in their clinics.

Results
120 HCPs (61 surgeons; 41 nurses; 9 oncologists; 9 other) attended 12 workshops. Knowledge scores (mean change = 6.58; 95% CI 6.00 to 7.17; p<0.001), and self-confidence (mean change = 2.64; 95% CI 2.33 to 2.95; p<0.001) improved significantly post workshop. Ratings for the facilitators’ approach were uniformly high (mean range 9.6 to 9.9 /10). Most delegates found the workshops useful, enjoyable, and informative and 98% would definitively recommend them to colleagues. Follow-up data (n = 72/96) showed that 57% believed attendance had improved their own practice when discussing genetic testing with their patients. When asked about mainstreaming more generally, 78% reported it was working well, 18% had not yet started, and 3% thought it was problematic in their centre.

Conclusions
Discussing the implications that having a pathogenic gene alteration has for patients’ treatment and risk-reducing interventions is complex when patients are already coming to terms with a breast cancer diagnosis. Training facilitators enhanced the wider roll-out of the TRUSTING educational programme and is an effective means of helping HCPs now involved in the mainstreaming of genetic testing.
Are protective measures against Covid-19 still active in orthodontic practices? A cross-sectional online survey of French orthodontists three years on from the pandemic
Authors: Loiseau Astrid , Davit-Béal Tiphaine , Brézulier Damien 
Published: July 2024

Purpose
The Covid-19 epidemic has imposed profound changes on the practice of orthodontics. It was in this anxiety-inducing context that drastic measures were imposed on orthodontists. The main aim of this online survey is to highlight the measures that are still in place in French orthodontic practices three years after the emergence of the pandemic.

Methods
A cross-sectional online survey was distributed to French orthodontists from march to June 2023. The questionnaire, consisting of 32 questions, was divided into five sections covering habits before and after the pandemic, and the feelings of professionals.

Results
In this survey 230 complete answers were recorded. Three years later, the daily pace had returned to its pre-crisis level. Disinfection and aeration times were still present (p < 0.001). Orthodontists maintained and generalized the use of protective glasses (p = 0.17) and visors (p < 0.001). The same was true for the FFP2 mask and its frequency of change, as well as rigorous hand washing. Finally, the dedicated layout of the practices was maintained: protective screen, filtration system, supply of SHA, travel paths, removal of magazines (for all, p < 0.001).

Conclusion
This study shows that the professional practices imposed by the Covid-19 crisis have been adopted by the majority of French orthodontists, and now appear to be anchored in their routine practice.

Trial registration number
opinion n°2023–004, dated 01.25.2023.
Foustaneles Kai Chlamydes: Istoriki Mnimi Kai Ethniki Taftotita, 1821–1903 (‘Kilts and Togas: Historical Memory and National Identity, 1821–1930’), Christina Koulouri (2020)
Authors: Kornetis Kostis 
Published: July 2024

Review of: Foustaneles Kai Chlamydes: Istoriki Mnimi Kai Ethniki Taftotita, 1821–1903 (‘Kilts and Togas: Historical Memory and National Identity, 1821–1930’), Christina Koulouri (2020)
Athens: Alexandria, 608 pp.,
ISBN 978-9-60221-886-0, p/bk, €26.50
I Istoria Tis Mousikis Tou Ethnikou Theatrou 1932–2005: Apo Tin Ethniki Mousiki Scholi Stin Protoporia (‘The history of the music of the national theatre 1932–2005: From the National Music School to the avant-garde’) Nikolaos Mamalis (2023)
Authors: Bezantakou Olga 
Published: July 2024

Review of: I Istoria Tis Mousikis Tou Ethnikou Theatrou 1932–2005: Apo Tin Ethniki Mousiki Scholi Stin Protoporia (‘The history of the music of the national theatre 1932–2005: From the National Music School to the avant-garde’) Nikolaos Mamalis (2023)
Athens: Fagotto books, 366 pp.,
ISBN 978-9-60668-596-5, p/bk, €25.00
Black Mirror: O Mavros Kathreftis Tis Psifiakotitas (The Black Mirror of Digitality), Despina Katapoti (ed.) (2022)
Authors: Zouli Ioanna 
Published: July 2024

Review of: Black Mirror: O Mavros Kathreftis Tis Psifiakotitas (The Black Mirror of Digitality), Despina Katapoti (ed.) (2022)
Athens: Kastanioti Editions, 457 pp.,
ISBN 978-9-60037-052-2, p/bk, €20.00
Optimizing Play: Why Theorycrafting Breaks Games and How to Fix It, Christopher A. Paul (2024)
Authors: Johnson Matthew S. S. 
Published: July 2024

Review of: Optimizing Play: Why Theorycrafting Breaks Games and How to Fix It, Christopher A. Paul (2024)
Cambridge, MA: The MIT Press, 189 pp.,
ISBN 978-0-26237-833-8, e-book
Identification and in silico screening of natural phloroglucinols as potential PI3Kα inhibitors: A computational approach for drug discovery
Authors: Siddique Farhan , Daoui Ossama , Ayoub Monisa , Elkhattabi Souad , Chtita Samir , Afzal Samina , Mohyuddin Abrar , Kaukab Iram , Ejaz Syeda Abida , Salamatullah Ahmad Mohammad , Ibenmoussa Samir , Wondmie Gezahign Fentahun , Bourhia Mohammed 
Published: July 2024

Abstract
Breast cancer is the biggest cause of death among women worldwide. Natural chemicals from medicinal plants offer promise for cancer therapy. This research screens 29 Dryopteris species plant-derived chemicals, mostly phloroglucinols, for breast cancer therapy potential. First, we used Gaussian09 and DFT/B3LYP/6-311+G(d, p) calculations to evaluate compound stability and reactivity. We conducted molecular docking experiments to identify drugs with high binding affinity for the PI3Kα protein’s active pocket. DJ1–DJ22 were found to be the most effective PI3Kα inhibitors, with energies ranging from −8.0 to −9.2 kJ/mol. From in silico pharmacokinetic and bioactivity screening, DJ3, DJ7, and DJ18 were identified as promising PI3Kα inhibitors. PI3Kα backbone stability was tested in a water model using molecular dynamics simulations employing DJ3, DJ7, DJ18, and Trastuzumab as a pharmacological reference. Synthesis of target-hit DJ3, DJ7, and DJ18 derivatives may lead to breast cancer drug-like molecules for related cancers. The work uses in silico methods to find natural phloroglucinols for breast cancer therapy, enabling new chemotherapeutic drugs.
Optimizing asphalt binder performance with various PET types
Authors: Abdulhasan Israa K. , Joni Hasan H. , Saadoon Tahseen D. , Dulaimi Anmar 
Published: July 2024

Abstract
The efficacy of a pavement system is significantly influenced by the condition of the road pavement. Improving pavement quality is essentially the key to reducing problems with fatigue cracks and rutting on roads. One of its tenets is changing and enhancing asphalt’s performance by use of various additives. One of the plastics having the highest recycling rates across various nations is polyethylene terephthalate, or PET. Since virgin PET (V-PET) and recycled PET (R-PET) cannot currently be analytically separated from one another, numerous indirect approaches have been developed to achieve this. According to one idea, recycling PET causes polymer chains to break, which alters the material’s structural, mechanical, and thermal characteristics. R-PET and V-PET can therefore be distinguished from one another. Temperature and load stress cause asphalt pavement damage, especially rutting. In order to reduce the issue of road rutting, several measures have been implemented, such as enhancing the quality of pavement and improving the procedures used for structural design. In recent years, engineers have shown a growing interest in enhancing the performance of asphalt by incorporating various additives and substituting raw materials with virgin and recycled materials. This approach aims to improve environmental sustainability and reduce the cost of modified pavement mixtures. The purpose of the study is to assess the effect of modifying bitumen of grade 40–50 with V-PET. This study examined the use of V-PET as an asphalt modifier, at varying concentrations of 1, 2, and 4% by weight of asphalt. The study aimed to assess the influence of these concentrations on the performance of asphalt under high temperature conditions. The results demonstrated that the addition of 2% V-PET to the asphalt binder significantly improved the characteristics of the asphalt, resulting in increased resistance to rutting in the pavement.
Exploring the potential of Delphastus
davidsoni (Coleoptera: Coccinellidae) in the biological control of Bemisia tabaci MEAM 1 (Hemiptera: Aleyrodidae)
Authors: Canassa Vinícius F. , Marchi-Werle Lia , Schlick-Souza Eunice C. , Fernandes da Silva Ivana , Lopes Baldin Edson L. 
Published: July 2024

Abstract
Coleopterans within the family Coccinellidae play an important role in the biological control of Bemisia tabaci MEAM1 Gennadius (Hemiptera: Aleyrodidae), a worldwide pest. Here we report an initial assessment of the predatory capacity and biological aspects of a South American coccinellid, Delphastus davidsoni Gordon (Coleoptera: Coccinellidae) to B. tabaci immature stages under laboratory conditions. Within the 24 h after release, D. davidsoni adults were increasingly more attracted to and consumed six times more B. tabaci fourth instar nymphs than the remaining immature stages. Similarly, D. davidsoni larvae also had a greater consumption of B. tabaci fourth instar nymphs within 24 h after release. Within 10 days after larvae release, there were no significant differences in preference between the nymphal stages. Both D. davidsoni adults and larvae presented a better biological performance when fed with B. tabaci fourth instar nymphs. The larval developmental time and pupal survival for D. davidsoni was optimal when fed fourth instar nymphs. These findings highlight the potential for implementing D. davidsoni in integrated pest management (IPM) programs for B. tabaci and warrant further evaluation under greenhouse and semi-field conditions.
Teaching Chinese grammar through International Chinese Language Education micro-lectures: negotiating mass and presence through multimodal pedagogic discourse
Authors: Yu Zhigang 
Published: July 2024

Abstract
Micro-lectures have become a prevailing resource for teaching Chinese grammar in International Chinese Language Education (ICLE). One crucial feature of these lectures is that they are inherently multimodal and the design of multimodal pedagogic discourse in these lectures is vital for the teaching of Chinese grammar. Based on this background, this paper investigates teaching Chinese grammar through multimodal pedagogic discourse in ICLE micro-lectures, focusing on the organization of complexity and abstraction of meaning for knowledge-building. Drawing on Systemic Functional Linguistics’ genre theory and ideational mass and presence, this paper views the organization as a dynamic negotiation of mass and presence across generic stages. Analyzing a representative ICLE micro-lecture on grammar, it scrutinizes the distribution of mass and presence across stages, along with multimodal pedagogic discourse features. The findings show that Presenting Scenarios, Example Extraction, and Grammar Explanation are pivotal stages for grammar instruction, each characterized by distinct mass and presence. Presenting Scenarios, featuring relatively weak mass and strong presence, employs non-technical and concrete multimodal texts to depict everyday scenarios, while Example Extraction with similar mass but weaker presence recontextualizes these scenarios into linguistic phenomena through non-technical linguistic text. Grammar Explanation characterized by relatively strong mass and weak presence distills grammatical knowledge from example sentences through technical and abstract linguistic text. Overall, the weakening of presence across the stages allows for recontextualizing scenario-based sentences as linguistic phenomena and generalizing these sentences into abstract grammatical concepts, while the strengthening of mass enables distilling meaning from example sentences and builds the complexity of grammatical concepts. The findings hold potential implications for the design of ICLE micro-lectures on Chinese grammar, which aims to facilitate the teaching of Chinese grammar through multimodal pedagogical discourse.