bluuebunny/crossref_metadata_2025_split huggingface dataset:
Improved spectral dynamic features extracted from audio data for classification of marine vessels
Authors: de Brito Santos Murillo , de Moraes Calazan Rogério 
Published: June 2024

AbstractUnderwater sound classification presents a unique challenge due to the complex propagation characteristics of sound in water, including absorption, scattering, and refraction. These complexities can distort and alter spectral features, hindering the effectiveness of traditional feature extraction methods for vessel classification. To address this challenge, this study proposes a novel feature extraction method that combines Mel-frequency cepstral coefficients (MFCCs) with a spectral dynamic feature (SDF) vector. MFCCs capture the spectral content of the audio signal, whereas SDF provides information on the temporal dynamics of spectral features. This combined approach aims to achieve a more comprehensive representation of underwater vessel sounds, potentially leading to improved classification accuracy. Validation with real-world underwater audio recordings demonstrated the effectiveness of the proposed method. Results indicated an improvement of up to 94.68% in classification accuracy when combining SDF with several classical extractors evaluated. This finding highlights the potential of SDF in overcoming the challenges associated with underwater sound classification.
Small Fires, Big Impact: Evaluating Fire Emission Estimates in Southern Africa Using New Satellite Imagery of Burned Area and Carbon Monoxide
Authors: van der Velde I. R. , van der Werf G. R. , van Wees D. , Schutgens N. A. J. , Vernooij R. , Houweling S. , Tonucci E. , Chuvieco E. , Randerson J. T. , Frey M. M. , Borsdorff T. , Aben I. 
Published: June 2024

AbstractVarious fire emission estimates for southern Africa during 2019, derived with multiple burned area data sets with resolutions ranging from 500 to 20 m, are evaluated using satellite carbon monoxide (CO) observations. Southern African emissions derived from burned area generated by 20 m Sentinel‐2 satellite imagery are up to 120% higher than other estimates because small fires are better detected with a higher‐resolution satellite instrument. A comprehensive comparison between simulated and observed atmospheric CO indicates that the Sentinel‐2 burned area data significantly improves emission estimates, with up to 15% reduction in CO concentration biases in comparison to emissions based on coarser resolution burned area data. We also found that the temporal lag between emissions and atmospheric CO concentrations during the peak fire month was related to atmospheric transport. These findings emphasize the importance of utilizing higher‐resolution satellite instruments in accurately estimating emissions and understanding the impact of small fires on global climate.
Plasma Sheet Counterparts for Auroral Beads and Vortices in Advance of Fast Flows: New Evidence for Near‐Earth Substorm Onset
Authors: Babu S. S. , Mann I. R. , Donovan E. F. , Smith A. W. , Dimitrakoudis S. , Sydora R. D. , Kale A. 
Published: June 2024

AbstractThe relationship between auroral, ground, and plasma sheet signatures in the late growth phase is crucial for understanding the sequence of events during a substorm expansion phase onset. Here we show conjugate ground‐auroral‐satellite observations of a substorm that occurred on 18 September 2021, between 04:45 and 05:00 UT, where four auroral activations were detected in the all‐sky imagers. An initial activation showed the brightening of an equatorward arc within the cutoff of the 630 nm emissions, indicating activity on closed field lines well inside the open‐closed field line boundary (OCFLB). During a second activation, auroral beads were observed on a brightening arc, equatorward and within the OCFLB, followed by the transformation from small‐scale to large‐scale vortices. The tail current sheet was highly disturbed during the auroral vortex evolution, including pressure and magnetic disturbances, an apparent broadening of a previously thin current sheet, and a breakdown of the frozen‐in condition. Our observations clearly show late growth phase dynamics, including arc brightenings, the formation of auroral beads, and auroral vortex development, can occur well in advance of fast Earthward flows in the tail. Indeed, it is only during that later activity that auroral breakup and strong Earthward flows, which we associate with magnetic reconnection further down the tail, are observed together with strong magnetic bays on the ground. The sequence of events is consistent with an inside‐to‐outside model at substorm expansion phase onset, most likely via a shear‐flow ballooning instability in the transition region from dipole to tail‐like fields in the near‐Earth plasma sheet.
A Statistical Study of Space Hurricanes in the Southern Hemisphere
Authors: Lu Sheng , Xing Zan‐Yang , Zhang Qing‐He , Zhang Yong‐Liang , Yang Hui‐Gen , Oksavik Kjellmar , Lyons L. R. , Lockwood Michael , Ma Yu‐Zhang , Wang Xiang‐Yu , Deng Zhong‐Xin , Xu Tong , Li Guo‐Jun , Wang Yong , Zhang Duan 
Published: June 2024

AbstractThe space hurricane is a large‐scale three‐dimensional magnetic vortex structure that can cause massive local energy injections in the polar cap. By analyzing Defense Meteorological Satellite Program (DMSP) F16–F19 satellite observations from 2005 to 2016, we found that the Southern Hemisphere space hurricane mainly occurs in summer under negative By dominated northward interplanetary magnetic field (IMF) conditions. In particular, the space hurricanes are more likely to occur in the dayside polar cap at magnetic latitude greater than 80°. The characteristics for the Southern Hemisphere are basically consistent with the characteristics of space hurricanes in the Northern Hemisphere. The different dependences of By component in different hemispheres supports the high‐latitude lobe reconnection as the formation mechanism. Plasma data from DMSP satellites in both hemispheres show that the appearance of the space hurricane greatly enhances the convection in the polar cap and the electron density on its dawn side. Within the space hurricane, electron temperatures typically increase significantly, accompanied by strong upward field‐aligned currents and electron precipitation. These results give us a better understanding of the solar wind‐magnetosphere‐polar ionosphere coupling process under northward IMF conditions.
Long-term climatic stability drives accumulation and maintenance of divergent freshwater fish lineages in a temperate biodiversity hotspot
Authors: Buckley Sean James , Brauer Chris J. , Unmack Peter J. , Hammer Michael P. , Adams Mark , Beatty Stephen J. , Morgan David L. , Beheregaray Luciano B. 
Published: June 2024

AbstractAnthropogenic climate change is forecast to drive regional climate disruption and instability across the globe. These impacts are likely to be exacerbated within biodiversity hotspots, both due to the greater potential for species loss but also to the possibility that endemic lineages might not have experienced significant climatic variation in the past, limiting their evolutionary potential to respond to rapid climate change. We assessed the role of climatic stability on the accumulation and persistence of lineages in an obligate freshwater fish group endemic to the southwest Western Australia (SWWA) biodiversity hotspot. Using 19,426 genomic (ddRAD-seq) markers and species distribution modelling, we explored the phylogeographic history of western (Nannoperca vittata) and little (Nannoperca pygmaea) pygmy perches, assessing population divergence and phylogenetic relationships, delimiting species and estimating changes in species distributions from the Pliocene to 2100. We identified two deep phylogroups comprising three divergent clusters, which showed no historical connectivity since the Pliocene. We conservatively suggest these represent three isolated species with additional intraspecific structure within one widespread species. All lineages showed long-term patterns of isolation and persistence owing to climatic stability but with significant range contractions likely under future climate change. Our results highlighted the role of climatic stability in allowing the persistence of isolated lineages in the SWWA. This biodiversity hotspot is under compounding threat from ongoing climate change and habitat modification, which may further threaten previously undetected cryptic diversity across the region.
An efficient point cloud semantic segmentation network with multiscale super-patch transformer
Authors: Miao Yongwei , Sun Yuliang , Zhang Yimin , Wang Jinrong , Zhang Xudong 
Published: June 2024

AbstractEfficient semantic segmentation of large-scale point cloud scenes is a fundamental and essential task for perception or understanding the surrounding 3d environments. However, due to the vast amount of point cloud data, it is always a challenging to train deep neural networks efficiently and also difficult to establish a unified model to represent different shapes effectively due to their variety and occlusions of scene objects. Taking scene super-patch as data representation and guided by its contextual information, we propose a novel multiscale super-patch transformer network (MSSPTNet) for point cloud segmentation, which consists of a multiscale super-patch local aggregation (MSSPLA) module and a super-patch transformer (SPT) module. Given large-scale point cloud data as input, a dynamic region-growing algorithm is first adopted to extract scene super-patches from the sampling points with consistent geometric features. Then, the MSSPLA module aggregates local features and their contextual information of adjacent super-patches at different scales. Owing to the self-attention mechanism, the SPT module exploits the similarity among scene super-patches in high-level feature space. By combining these two modules, our MSSPTNet can effectively learn both local and global features from the input point clouds. Finally, the interpolating upsampling and multi-layer perceptrons are exploited to generate semantic labels for the original point cloud data. Experimental results on the public S3DIS dataset demonstrate its efficiency of the proposed network for segmenting large-scale point cloud scenes, especially for those indoor scenes with a large number of repetitive structures, i.e., the network training of our MSSPTNet is much faster than other segmentation networks by a factor of tens to hundreds.
Hodgkin lymphoma: hypodense lesions in mediastinal masses
Authors: Damek Adrian , Kurch Lars , Franke Friedrich Christian , Attarbaschi Andishe , Beishuizen Auke , Cepelova Michaela , Ceppi Francesco , Daw Stephen , Dieckmann Karin , Fernández-Teijeiro Ana , Feuchtinger Tobias , Flerlage Jamie E. , Fosså Alexander , Georgi Thomas W. , Hasenclever Dirk , Hraskova Andrea , Karlen Jonas , Klekawka Tomasz , Kluge Regine , Körholz Dieter , Landman-Parker Judith , Leblanc Thierry , Mauz-Körholz Christine , Metzler Markus , Pears Jane , Steglich Jonas , Uyttebroeck Anne , Vordermark Dirk , Wallace William Hamish , Wohlgemuth Walter Alexander , Stoevesandt Dietrich 
Published: June 2024

AbstractHypodense volumes (HDV) in mediastinal masses can be visualized in a computed tomography scan in Hodgkin lymphoma. We analyzed staging CT scans of 1178 patients with mediastinal involvement from the EuroNet-PHL-C1 trial and explored correlations of HDV with patient characteristics, mediastinal tumor volume and progression-free survival. HDV occurred in 350 of 1178 patients (29.7%), typically in larger mediastinal volumes. There were different patterns in appearance with single lesions found in 243 patients (69.4%), multiple lesions in 107 patients (30.6%). Well delineated lesions were found in 248 cases (70.1%), diffuse lesions were seen in 102 cases (29.1%). Clinically, B symptoms occurred more often in patients with HDV (47.7% compared to 35.0% without HDV (p = 0.039)) and patients with HDV tended to be in higher risk groups. Inadequate overall early-18F-FDG-PET-response was strongly correlated with the occurrence of hypodense lesions (p < 0.001). Patients with total HDV > 40 ml (n = 80) had a 5 year PFS of 79.6% compared to 89.7% (p = 0.01) in patients with HDV < 40 ml or no HDV. This difference in PFS is not caused by treatment group alone. HDV is a common phenomenon in HL with mediastinal involvement.
An entropy based spatial–temporal cube with its application to assess stress of overburden due to mining
Authors: Yang Changde , Chen Yang , Yang Binbin , Huang Chunshui 
Published: June 2024

Abstract
Underground coal seam mining significantly alters the stress and energy distribution within the overlying rock, leading to eventual structural degradation. Therefore, it is imperative to quantitatively identify the temporal and spatial characteristics of stress evolution of overlying rock caused by mining. This paper introduces a novel rock stress model integrating entropy and a spatial–temporal cube. Similar material model tests are used to identify the abrupt entropy changes within the mining rock, and the trend analysis is carried out to describe the spatial–temporal evolution law of stress during mining. Experimental findings indicate elevated stress levels in the unmined rock preceding and following the panel, as well as within specific rock strata above it. Definitively, dynamic stress arches within the surrounding rock of the stope predominantly bear and distribute the load and pressure from the overlying rock, and each stress mutation is accompanied by a sudden stress entropy change. Over time, z-score shows that the noticeable reduction in mining-induced overburden stress becomes increasingly pronounced, especially in the water-conducting fracture zone. The model's bifurcation set serves as the comprehensive criterion for the entropy-induced sudden changes in the rock system, signifying overall failure.
Does immunohistochemical marker conversion affect the prognosis in breast cancer patients receiving neoadjuvant chemotherapy?
Authors: Uzun Mehmet , Atag Elif , Caliskan Yildirim Eda , Keser Murat , Semiz Huseyin Salih , Unal Olcun Umit 
Published: June 2024

AbstractBiomarkers such as hormone receptors (HR) and human epidermal growth factor receptor2 (HER2) may change after neoadjuvant chemotherapy (NAC) in breast cancer patients. The aim of this study was to investigate the rates of receptor change after NAC and to evaluate the prognostic impact of change. Patients with breast cancer who received NAC were included in the study. Changes in pathological findings (ER, PR, HER-2, Ki-67, grade) before and after NAC were examined. In addition, the effect of receptor exchange on prognosis was evaluated. Kaplan Meier analysis was used for survival analyses. Study was approved by Ethics Board of Tepecik Training and Research Hospital (Decision number 2021/10-02). We confirm that all methods were performed in accordance with relevant named guidelines and regulations. The study included 203 female patients. When pathological findings before and after NAC were compared, significant regression was found in grade and Ki-67 values (p = 0.003, p < 0.001). ER change rate was 11.8%, PR change rate was 24.6% and HER-2 change rate was 12.5%. No significant correlation was found between ER, PR and HER-2 changes and prognosis. The pathological T stage after NAC being 1 or 2, no lymph nodes detected, and the tumor grade being 1 or 2 were independent variables related to survival (p: 0.002, p: 0.014, p < 0.001). In patients with breast cancer, it would be appropriate to re-evaluate the HER-2 and HR status of the surgical specimen following NAC, especially in initially negative patients. The correlation of receptor discordance with prognosis is not clear and more extensive studies are needed.
Acute Ascaris infection impairs the effector functions of natural killer cells in single and Salmonella co-infected pigs
Authors: Mugo Robert M. , Oser Larissa , Midha Ankur , Adjah Joshua , Kundik Arkadi , Laubschat Alexandra , Höfler Philipp , Musimbi Zaneta D. , Hayani Rima , Schlosser-Brandenburg Josephine , Hartmann Susanne , Rausch Sebastian 
Published: June 2024

AbstractNatural killer (NK) cells play a key role in defense against Salmonella infections during the early phase of infection. Our previous work showed that the excretory/secretory products of Ascaris suum repressed NK activity in vitro. Here, we asked if NK cell functionality was influenced in domestic pigs during coinfection with Ascaris and Salmonella enterica serotype Typhimurium. Ascaris coinfection completely abolished the IL-12 and IL-18 driven elevation of IFN-γ production seen in CD16 + CD8α + perforin + NK cells of Salmonella single-infected pigs. Furthermore, Ascaris coinfection prohibited the Salmonella-driven rise in NK perforin levels and CD107a surface expression. In line with impaired effector functions, NK cells from Ascaris-single and coinfected pigs displayed elevated expression of the inhibitory KLRA1 and NKG2A receptors genes, contrasting with the higher expression of the activating NKp46 and NKp30 receptors in NK cells during Salmonella single infection. These differences were accompanied by the highly significant upregulation of T-bet protein expression in NK cells from Ascaris-single and Ascaris/Salmonella coinfected pigs. Together, our data strongly indicate a profound repression of NK functionality by an Ascaris infection which may hinder infected individuals from adequately responding to a concurrent bacterial infection.
Manufacturing and preclinical toxicity of GLP grade gene deleted attenuated Leishmania donovani parasite vaccine
Authors: Avishek Kumar , Beg Mirza A. , Vats Kavita , Singh Avinash Kumar , Dey Ranadhir , Singh Kamaleshwar P. , Singh Rajesh Kumar , Gannavaram Sreenivas , Ramesh V. , Mulla Mohmad Sadik A. , Bhatnagar Upendra , Singh Sanjay , Nakhasi Hira L. , Salotra Poonam , Selvapandiyan Angamuthu 
Published: June 2024

AbstractCentrin1 gene deleted Leishmania donovani parasite (LdCen1−/−) was developed and extensively tested experimentally as an intracellular stage-specific attenuated and immunoprotective live parasite vaccine candidate ex vivo using human PBMCs and in vivo in animals. Here we report manufacturing and pre-clinical evaluation of current Good-Laboratory Practice (cGLP) grade LdCen1−/− parasites, as a prerequisite before proceeding with clinical trials. We screened three batches of LdCen1−/− parasites manufactured in bioreactors under cGLP conditions, for their consistency in genetic stability, attenuation, and safety. One such batch was preclinically tested using human PBMCs and animals (hamsters and dogs) for its safety and protective immunogenicity. The immunogenicity of the CGLP grade LdCen1−/− parasites was similar to one grown under laboratory conditions. The cGLP grade LdCen1−/− parasites were found to be safe and non-toxic in hamsters and dogs even at 3 times the anticipated vaccine dose. When PBMCs from healed visceral leishmaniasis (VL) cases were infected with cGLP LdCen1−/−, there was a significant increase in the stimulation of cytokines that contribute to protective responses against VL. This effect, measured by multiplex ELISA, was greater than that observed in PBMCs from healthy individuals. These results suggest that cGLP grade LdCen1−/− manufactured under cGMP complaint conditions can be suitable for future clinical trials.
MXene-based novel nanocomposites doped SnO2 for boosting the performance of perovskite solar cells
Authors: Alhamada T. F. , Hanim M. A. Azmah , Jung D. W. , Saidur R. , Nuraini A. A. , Hasan W. Z. Wan , Tan K. H. , Noh M. Mohamad , Teridi M. A. M. 
Published: June 2024

AbstractSince being first published in 2018, the use of two-dimensional MXene in solar cells has attracted significant interest. This study presents, for the first time, the synthesis of an efficient hybrid electrocatalyst in the form of a nanocomposite (MXene/CoS)-SnO2 designed to function as a high-performance electron transfer layer (ETL). The study can be divided into three distinct parts. The first part involves the synthesis of single-layer Ti3C2Tx MXene nanosheets, followed by the preparation of a CoS solution. Subsequently, in the second part, the fabrication of MXene/CoS heterostructure nanocomposites is carried out, and a comprehensive characterization is conducted to evaluate the physical, structural, and optical properties. In the third part, the attention is on the crucial characterizations of the novel nanocomposite-electron transport layer (ETL) solution, significantly contributing to the evolution of perovskite solar cells. Upon optimising the composition, an exceptional power conversion efficiency of more than 17.69% is attained from 13.81% of the control devices with fill factor (FF), short-circuit current density (Jsc), and open-circuit voltage (Voc) were 66.51%, 20.74 mA/cm2, and 1.282 V. Therefore, this PCE is 21.93% higher than the control device. The groundbreaking MXene/CoS (2 mg mL−1) strategy reported in this research represents a promising and innovative avenue for the realization of highly efficient perovskite solar cells.
Screening of sugarcane germplasm against Sporisorium scitamineum and its effects on setts germination and tillering
Authors: Rajput Muhammad Aslam , Iqbal Owais , Syed Rehana Naz , Elsalahy Heba H. , Rajput Nasir Ahmed , Ahmad Sagheer , Khan Rizwan , Khanzada Muhammad Ali , Younas Muhammad Usama , Qasim Muhammad , Rizwana Humaira , Almaary Khalid S. , Iqbal Rashid , Lodhi Abdul Mubeen 
Published: June 2024

AbstractSugarcane smut is the most damaging disease that is present almost across the globe, causing mild to severe yield losses depending upon the cultivar types, pathogen races and climatic conditions. Cultivation of smut-resistant cultivars is the most feasible and economical option to mitigate its damages. Previous investigations revealed that there is a scarcity of information on early detection and effective strategies to suppress etiological agents of smut disease due to the characteristics overlapping within species complexes. In this study, 104 sugarcane cultivars were screened by artificial inoculation with homogenate of all possible pathogen races of Sporisorium scitamineum during two consecutive growing seasons. The logistic smut growth pattern and the disease intrinsic rate were recorded by disease growth curve. Variable levels of disease incidence i.e., ranging from 0 to 54.10% were observed among these sugarcane cultivars. Besides, pathogen DNA in plant shoots of all the cultivars was successfully amplified by PCR method using smut-specific primers except 26 cultivars which showed an immune reaction in the field trial. Furthermore, the plant germination and tillering of susceptible sugarcane cultivars were greatly influenced by pathogen inoculation. In susceptible cultivars, S. scitamineum caused a significant reduction in setts germination, coupled with profuse tillering, resulting in fewer millable canes. Correlation analysis demonstrated that there was a positive relationship between reduction in setts germination and increase in the number of tillers. The present study would be helpful for the evaluation of smut resistance in a wide range of sugarcane germplasm, especially from the aspects of setts germination and tillers formation, and it also screened out several excellent germplasm for potential application in sugarcane breeding.