bluuebunny/crossref_metadata_2025_split huggingface dataset:
Trace Spectrophotometric Determination of Dichlorvos using Diphenyl Semicarbazide (DPC) in Environmental and Agricultural Samples
Authors: Janghel E. K. , Rai M. K. , Gupta V. K. , Rai J. K. 
Published: May 2015

AbstractA new and highly sensitive spectrophotometric method is developed for the determination of sub ppm levels of the widely used organophosphorus insecticide dichlorvos. The method is based on alkaline hydrolysis of dichlorvos to dichloroacetaldehyde followed by coupling with diphenyl semicarbazide (DPC) in alkaline medium. The absorption maxima of the wine red dye compound formed is measured at 490 nm. Beer's law is obeyed over the concentration range of 4.3 to 34 μg in a final solution volume of 25 mL (0.18–1.36 ppm). The molar absorptivity, Sandell's sensitivity and correlation coefficient were found to be 2.9 × 105 l mole−1 cm−1, 0.013 μg cm−2 and 0.9999, respectively. The standard deviation and relative standard deviation were found to be ± 0.007 and 1.90%, respectively. The lower limit of detection is 0.04 μg. The method is simple, sensitive and free from interferences of other pesticides and diverse ions. Other organophosphorous pesticides do not interfere with the proposed method. The method has been satisfactorily applied to the determination of dichlorvos in environmental and agricultural samples.
Effects of Neodymium on the Properties of Ni‐B/CNTs Amorphous Alloy Catalyst
Authors: Hu Chang‐Yuan , Li Feng‐Yi , Zhang Rong‐Bin , Liao Xiao‐Ning , Hua Li 
Published: May 2015

AbstractNeodymium is used as a promoter of Ni‐B/CNTs amorphous alloy catalyst to modify its catalytic properties. Ni‐B/CNTs and Ni‐Nd(5wt%)‐B/CNTs catalysts were prepared by the impregnation chemical reduction method. Their catalytic performances were examined in acetylene selective hydrogenation, which is a crucial step in industrial polymerization processes, with the aim of the complete elimination of alkynes from alkene feedstocks. Experiments showed that the latter exhibited higher acetylene hydrogenation activity but lower ethylene selectivity. Catalysts were characterized by ICP, CO‐chemisorption, XPS, XRD and H2‐TPD techniques. On the basis of characterizations, the modification of Nd on Ni‐B/CNTs catalyst was related to its geometric and electronic effects.
Sensitivity in Supramolecular Architectures of Polyaromatic Salts Containing Two Singly‐Pimerized Bipyridines
Authors: Liu Shih‐An , Kuo Ting‐Shen , Lee Gene‐Hsiang , Shiu Kom‐Bei 
Published: May 2015

AbstractThree novel supramolecular arrays of zigzag polyaromatic salts are reported. Both the conformation and disposition of the dications are subjected to various noncovalent interactions. Thus, the presence or absence of the π‐π interacting enclathrated molecules, the efficient packing and the involved hydrogen bonding interactions of anions, as well as the increased hydrophobic property of the dications themselves exert influence.
The Study of Indirect Determination of Tiopronin by Extraction Flotation Copper(II) with an Ammonium Sulfate‐Water‐n‐Propyl Alcohol System
Authors: Zhang Yu‐Ping , Li Quan‐Min , Zhao Xiao‐Hong , Liu Guo‐Guang 
Published: May 2015

AbstractA novel method for indirect determination of tiopronin by extraction flotation of copper(II) with an ammonium sulfate‐water‐n‐propyl alcohol system was developed. The effects of different parameters, such as acidity, the amount of NH4SCN and various salts on the flotation yield of Cu(II), have been studied to optimize the experimental conditions. Under the optimum conditions, Cu(II) is reduced to Cu(I) by tiopronin, and the resulting Cu(I) can react with SCN− to form a white emulsion precipitate CuSCN. In the presence of (NH4)2SO4, the mixture consisting of n‐propyl alcohol and water can be separated into an n‐propyl alcohol phase and a water phase. In the process of phase separation of n‐propyl alcohol from water, the precipitated CuSCN is extracted and stays in the interface of n‐propyl alcohol and water. The amount of tiopronin can be determined by measuring the flotation yield of Cu(II). The detection limit is 0.32 mg L−1 and the linear range is maintained in the range of 0.40±13.0 mg L−1 with a correlation coefficient of 0.9991. This proposed method has been successfully applied to the determination of tiopronin in tablets, urine and human plasma with satisfactory results.
Synthesis and Characterization of Poly(Biphenyl‐2‐yl p‐Styrenesulphonate) as Profungicide in Controlled Release Technique
Authors: Khazaei Ardeshir , Soudbar Davood , Sadri Minoo , Hosseini Hassan 
Published: May 2015

AbstractA new fungicide controlled release formulation was prepared by the reaction of p‐styrenesulphonyl chloride with biphenyl‐2‐ol (Dowicide A) as fungicide. The resulting monomer containing the fungicide was polymerized with benzoyl peroxide as initiator. The monomer and the polymer were identified by spectroscopic methods, and molecular weight of the polymer was determined by GPC. Also mp, Tg and Td of the polymer were identified by DSC. The release characteristic of the polymer was studied in neutral, alkaline, and acidic media. Also, the effect of the temperature on the release of bioactive agent (Dowicide A) was investigated. The hydrolysis data showed that the release rates are strongly dependent upon the pH of the medium and the temperature.
Synthesis and Cytotoxicity of 6‐Pyrrolidinyl‐2‐(2‐Substituted Phenyl)‐4‐Quinazolinones
Authors: Hour Mann‐Jen , Yang Jai‐Sing , Lien Jin‐Cherng , Kuo Sheng‐Chu , Huang Li‐Jiau 
Published: May 2015

AbstractIn our continuing search for potential anticancer candidates, 2‐(3‐methoxyphenyl)‐6‐pyrrolidinyl‐4‐quinazolinone (JJC‐1) was selected as the lead compound.Starting 5‐pyrrolidinyl‐2‐aminobenzamide was prepared using standard methodology from 5‐chloro‐2‐nitrobenzoic acid by reaction with SOCl2, NH3, pyrrolidine, and H2. The starting benzamide then was reacted with 2‐substituted benzaldehyde or benzoyl chloride in N,N‐dimethylacetamide (DMAC) in the presence of NaHSO3 at 150 °C. Thermal cyclodehydration/dehydrogenation gave the target 6‐pyrrolidinyl‐2‐(2‐substituted phenyl)‐4‐quinazolinones (15–22).These target compounds were assayed for their cytotoxicity in vitro against six cancer cell lines, including human monocytic leukemia cells (U937), mouse monocytic leukemia cells (WEHI‐3), human hepatoma cells (HepG2, Hep3B) and human lung carcinoma cells (A549, CH27). Most of them exhibited significant cytotoxic effect toward U937 and WEHI‐3 cells, with EC50 values ranging from 0.30 to 10.10 μM. Compound 19 was investigated further for its action mechanisms. Preliminary findings indicated that compound 19 induced G2/M arrest and apoptosis on U937 cells.
Poly(N‐Bromobenzene‐1,3‐Disulfonylamide), N,N,N′,N′‐Tetrabromobenzene‐1,3‐Disulfonylamide and DABCO‐Bromine Complex: As Novel Reagents for the Oxidative Coupling of Thiols to Disulfides
Authors: Ghorbani‐Vaghei Ramin , Zolfigol Mohammad Ali , Moshfeghifar Nasrin , Koukabi Nadiya , Chehardoli Gholamabbas 
Published: May 2015

AbstractAn efficient method for the oxidative coupling of thiols to their corresponding disulfides by new reagents poly(N‐bromobenzene‐1,3‐disulfonylamide) PBBS, N,N,N′,N′‐tetrabromobenzene‐1,3‐disulfonylamide TBBDA and DABCO‐bromine complex is described. The reaction was applicable to a variety of thiols with high chemoselectivity.
A Brief Catalyst Study on Direct Methane Conversion Using a Dielectric Barrier Discharge
Authors: Indarto Antonius , Choi Jae‐Wook , Lee Hwaung , Song Hyung Keun 
Published: May 2015

AbstractA series of metal catalysts was used for methane conversion to higher hydrocarbons and hydrogen in a dielectric barrier discharge. The main goal of this study is to identify the metal catalyst components which can influence the reactions in room‐temperature plasma conditions. The catalysts supported by γ‐Al2O3 and zeolite (ZSM 5x) were prepared by the incipient wetness method with solutions containing the metal ions of the second component. Among the catalysts tested, only Pt and Fe catalysts showed a unique result of catalytic reaction in a reactor bed packed with glass beads.
A Computational Study of 3‐D Helium Clusters
Authors: Sabzyan Hassan , Zanjanchi Farzaneh 
Published: May 2015

AbstractPhysical and thermodynamic properties have been calculated and analyzed for the best and optimized geometries of the 3‐D clusters with N = 3 to N = 10 atoms and unit cells of three types of crystalline systems using ab initio RHF/6–31G** method. Dependence of the lattice binding energy on the cluster parameter, R, has been studied. Similar behavior observed for the binding energies for all clusters shows that probabilities of their existence in the condensed phase are more or less the same. In the next step, thermodynamic properties have been calculated and analyzed for He27 3‐D helium clusters with simple cubic, body centered cubic (bcc), trigonal and hexagonal (hcp) configurations. The results show that the hexagonal cluster is more favored over other clusters. It is found that these clusters are electronically stable over a limited range of the values for the lattice parameter. ΔfH is constant in this stability region and thus the ΔfG exactly follows the variations of TΔfS. Surface effects have been investigated by comparing the square and hexagonal He9 2‐D lattices with the cubic and hexagonal He27 3‐D lattices, respectively. The lattice parameters, densities and molar volumes calculated for the clusters with hcp and bcc configurations have satisfactory agreement with the available experimental values. Properties of the He13, He34 and He104 hcp clusters have also been calculated and analyzed.
Analysis of Dynamic and Thermodynamic Adsorption of Nanoparticles on Solid Surfaces by Dark‐Field Light Scattering Measurements
Authors: Hu Cho‐Chun , Lin Jia‐Ching , Tseng Wei‐Lung , Huang Ming‐Feng , Chiu Tai‐Chia , Chang Huan‐Tsung 
Published: May 2015

AbstractWe have constructed a dark‐field light scattering microscope using a very low‐cost digital camera to investigate the adsorption of gold nanoparticles (AuNPs) on four different substrates at various pH values. The substrates used are glass, polycarbonate (PC), poly(dimethylsiloxane) (PDMS), and poly(methyl methacrylate) (PMMA). The coverage of AuNPs on hydrophobic substrates such as PDMS is greater than that on hydrophilic substrates like glass. The adsorption and aggregation of AuNPs on a particular substrate increased upon decreasing the pH (from 9.0 to 4.0). A greater coverage percentage of AuNPs, but less aggregation, occurs on glass treated with poly(diallyldimethylammonium) (PDDA) than on bare glass. The scattering intensity increases upon increasing the number of layers of adsorbed AuNPs on glass that was treated sequentially with AuNPs and PDDA. When compared to UV‐Vis absorption, dark‐field microscope provides greater sensitivity and qualitative surface information.
A Non‐Phosgene Route Synthesis of Carbamate in Continuous Fixed Bed Reactor
Authors: Liang Mong , Lee Tzung‐Jan , Huang Chih‐Chiao , Lin Kun‐Yu 
Published: May 2015

AbstractA non‐phosgene route synthesis of carbamate was carried out in a continuous fixed‐bed reactor through oxidative carbonylation of aniline using palladium catalysts and sodium iodide as promoter. The activity, selectivity and stability of both carbon and alumina‐supported palladium catalysts were evaluated. It was found that the alumina‐supported catalyst system exhibited a higher activity and selectivity than that of the carbon‐supported system, and an average aniline conversion of 95.6% and carbamate selectivity of 74.6% were achieved for the Se‐Pd/Al2O3 catalyst after 91 h on stream. Reclamation analysis of the spent Pd/C catalyst suggested that the deactivation was mainly due to the leaching and sintering of palladium metal and the accumulation of insoluble chemicals on catalyst support also aggravated the decline of catalyst activity. When small amounts of selenium were added to the Pd/Al2O3 catalyst, its activity, selectivity and stability were significantly improved which indicated that a promotional effect existed for carbamate formation on a Pd‐Se catalyst system.
Hydrothermal Synthesis and X‐Ray Structural Characterization of Manganese, Nickel, and Cadmium Coordination Polymers Containing 2,3‐Pyridinedicarboxylate as Multidentate Ligands
Authors: Yen Chia‐Hung , Chen Chun‐Yu , Shiu Kom‐Bei 
Published: May 2015

AbstractThree divalent transiton‐metal complexes of 2,3‐pyridinedicarboxylate (2,3‐pda2), [Mn(2,3‐pda)‐(H2O)3]∞ (7), [Ni(2,3‐pda)(H2O)3]∞ (8), and [Cd2(2,3‐pda)2(H2O)]∞ (9) have been hydrothermally synthesized and structurally characterized. X‐ray diffraction analyses reveal that compounds 7 and 8 are zigzag‐ and linear‐type one‐dimension (1D) coordination polymers, respectively, whereas compound 9 is a three‐dimension (3D) coordination polymer. A simple comparison of the coordination geometries with the available neutral analogues {Mx(2,3‐pda)x(H2O)y}∞ containing one or two divalent transition‐metal atoms and equal ligands in the presence or absence of coordinated water molecules is also presented.
Catalytic Method for Synthesis of Aspirin by a Green, Efficient and Recyclable Solid Acid Catalyst (Preyssler's Anion) at Room Temperature
Authors: Bamoharram Fatemeh F. , Heravi Majid M. , Roshani Mina , Gharib Ali , Jahangir Manouchehr 
Published: May 2015

AbstractSynthesis of aspirin at room temperature via O‐acetylation of salicylic acid in the presence of Preyssler type heteropolyacids has been investigated in order to contribute toward clean technology, which is the most important need of the society. All of the catalysts are recyclable and reusable.
Synthesis and Characterization of Dinuclear Ruthenium(II) Complexes Based on 4,4′‐Bipyridyl Type Bridging Ligands
Authors: Guckian Adrian L. , Browne Wesley R. , Hjelm Johan , Vos Johannes G. 
Published: May 2015

AbstractThe synthesis, spectroscopic, electrochemical and photophysical characterization of a series of dinuclear ruthenium(II) complexes of the type [(bpy)2Ru(NnN)2RuCl(bpy)2](PF6)3, where NnN = 4,4′‐bipyridyl (N0N), 1,2‐bis(4‐pyridyl)ethylene (NEN), 1,2‐bis(4‐pyridyl)ethane (N2N), and 4,4′‐trimethylenedipyridine (N3N) are reported. The photophysical and electrochemical properties are discussed with particular emphasis on the ability of the bridging ligands to support intercomponent interaction.
Adsorption Characteristics of Pb(II) and Cr(III) onto C‐4‐Methoxyphenylcalix[4]Resorcinarene in Batch and Fixed Bed Column Systems
Authors: Jumina  , Sarjono Ratnaningsih Eko , Paramitha Brajna , Hendaryani Ika , Siswanta Dwi , Santosa Sri Juari , Anwar Chairil , Sastrohamidjojo Hardjono , Ohto Keisuke , Oshima Tatsuya 
Published: May 2015

AbstractA study on the adsorption characteristics of Pb(II) and Cr(III) cations onto C‐4‐methoxyphenylcalix‐[4]resorcinarene (CMPCR) in batch and fixed bed column systems has been conducted. CMPCR was produced by one step synthesis from resorcinol, 4‐methoxybenzaldehyde, and HCl. The synthesis was carried out at 78 °C for 24 hours and afforded the adsorbent in 85.7% as a 3:2 mixture of C4ν:C2ν isomer. Most parameters in batch and fixed bed column systems confirm that CMPCR is a good adsorbent for Pb(II) and Cr(III), though Pb(II) adsorption was more favorable than that of Cr(III). The adsorption kinetic of Pb(II) and Cr(III) adsorptions in batch and fixed bed column systems followed a pseudo 2n order kinetics model. The rate constant of Pb(II) was higher than that of Cr(III) in the batch system, but this result was contrary to the result obtained in a fixed bed column system. Desorption studies to recover the adsorbed Pb(II) and Cr(III) were performed sequentially with distilled water and HCl, and the results showed that the adsorption was dominated by chemisorption.
Highly Sensitive and Selective Determination of Manganese in Tea Leaves by a Catalytic Kinetic Spectrophotometric Method
Authors: Fathi Mohammad Reza , Hashemi Payman , Abolhasan‐Oghly Mohammad Jafar 
Published: May 2015

AbstractThe catalytic effect of manganese(II) on the oxidation of barium diphenylamine sulfonate (BDAS) with potassium bromate in sulfuric acid was studied. Progress of the reaction was monitored, spectrophotometrically, by measuring absorbance changes at 547.5 nm. A highly sensitive, selective and simple method was accordingly developed for the determination of trace amounts of Mn(II), with no need for a separation or pre‐concentration step. Effects of reaction time, concentration of reagents, temperature and ionic strength on the reaction rate were studied. In the optimized conditions, manganese could be determined in a range of 1 to 60 ng mL−1 with a detection limit of 0.2 ng mL−1. The proposed method was successfully applied to the determination of manganese in tea leaves.
Microwave‐Assisted Oxidation of Alcohols with N,N,N′,N′‐Tetrabromobenzene‐1,3‐Disulfonamide and Poly(N‐Bromobenzene‐1,3‐Disulfonamide) under Solvent‐Free Conditions
Authors: Ghorbani‐Vaghei Ramin , Veisi Hojat , Amiri Mostafa 
Published: May 2015

AbstractAn efficient and mild methodology for the oxidation of primary and secondary alcohols to the corresponding carbonyl functions is described with N,N,N′,N′‐tetrabromobenzene‐1,3‐disulfonamide and poly(N‐bromobenzene‐1,3‐disulfonamide) using microwave irradiation under solvent‐free conditions. Aliphatic, benzylic and allylic alcohols are rapidly oxidized without over‐oxidation to carboxylic acids. Secondary carbinols are slowly oxidized so that the reaction is highly chemoselective.
Synthesis of Some Novel 2‐Anilinothiophene, 2,3′‐Bithienyl and Thienylthiopyridine Derivatives Resistance to Penicillium Digitatum Effect the Fruit
Authors: Al‐Omran Fatima , El‐Khair Adel Abou 
Published: May 2015

AbstractReaction of benzotriazol‐1‐yl acetone 1 with phenyl isothiocyanate followed with α‐chloroacetone or ethyl‐α‐chloroacetate afforded 2‐anilinothiophenes 3 or 4, respectively. Treatment of 3 with malononitrile at different reaction conditions afforded 6 or 7. Reaction of 1 with CS2 in DMF and phenacylbromide afforded S‐alkylated thiophene 10. Reactions of the latter compound with different active methylene nitriles afforded thienylthiopyridine derivatives 14 and 15. Condensation of 10 with hydrazine hydrate afforded hydrazon derivative 16. Reaction of thiophene 17 with formamide in DMF afforded 19 which converted to N‐thienylpyrimidine 20 when treated with malononitrile. The structure of the newly synthesized compounds has been established on the basis of their analytical and spectral data. The compounds were also investigated for antibacterial and antifungal activities.
Synthesis of 5‐(6‐Pyridazinone‐3‐yl)‐2‐Glycosylamino‐1,3,4‐Oxadiazoles
Authors: Tao Jing , Wang Duo‐Zhi , Cao Ling‐Hua 
Published: May 2015

AbstractN‐Glycosyl‐2‐(1,4,5,6‐tetrahydropyridazin‐6‐one‐3‐carbonyl)‐hydrazinecarbothioamides 3a‐3g and N‐glycosyl‐2‐(1,6‐dihydropyridazin‐6‐one‐3‐carbonyl)‐hydrazinecarbothioamides 5a‐5g were prepared by the reaction of glycosyl isothiocyanates with the compounds 1,4,5,6‐tetrahydro‐3‐hydrozinecarbonyl‐6‐pyridazinone (1) and 1,6‐dihydro‐3‐hydrozinecarbonyl‐6‐pyridazinone (2). The terminal heterocyclic compounds 1,3,4‐oxadiazole derivatives were obtained from cyclization of compounds (3a‐3g) and (5a‐5g) by mercuric acetate. Their structures were confirmed by IR, 1H NMR, MS and elemental analyses.
Convenient, Mild and One‐Pot Synthesis of Double Schiff Bases from Three Component Reaction of Salicylaldehyde, Ammonium Acetate and Aliphatic Aldehydes Accelerated by NEt3 as a Base
Authors: Naeimi Hossein , Rabiei Khadigeh 
Published: May 2015

AbstractA convenient and efficient procedure for one‐pot preparation of double Schiff bases through a three component reaction of salicylaldehyde, ammonium acetate and aliphatic aldehyde was described. In this reaction, N,N′‐bis(salicylidene)‐1,1‐diaminoalkanes was easily obtained in excellent yields and short reaction times under mild reaction condition.
Polymer‐Supported Thiocyanate as New, Versatile and Efficient Polymeric Reagent for Conversion of Alkyl Halides to Corresponding Alkyl Thiocyanates under Mild Conditions
Authors: Zarchi Mohammad Ali Karimi 
Published: May 2015

AbstractCrosslinked poly(N‐methyl‐4‐vinylpyridinium)thiocyanate [P4‐Me]SCN (II) is prepared easily and is used as a new polymeric reagent for synthesis of alkyl thiocyanates from alkyl halides under mild and nonaqueous conditions. The used polymeric reagent usually can be removing quantitatively and be regenerated.
Reaction of 2,3‐Dichloro‐1,4‐Naphthoquinone with 1‐Phenylbiguanide and 2‐Guanidinebenzimidazole
Authors: El‐Shaieb Kamal M. 
Published: May 2015

AbstractWhen 2,3‐dichloro‐1,4‐naphthoquinone (DCHNQ) (1) is allowed to react with 1‐phenylbiguanide (PBG) (2), 4‐chloro‐2,5‐dihydro‐2,5‐dioxonaphtho[1,2‐d]imidazole‐3‐carboxylic acid phenyl amide (4), 6‐chloro‐8‐phenylamino‐9H‐7,9,11‐triaza‐cyclohepta[a]naphthalene‐5,10‐dione (5) and 4‐dimethyl‐amino‐5,10‐dioxo‐2‐phenylimino‐5,10‐dihydro‐2H‐benzo[g]quinazoline‐1‐carboxylic acid amide (6) were obtained. While on reacting 1 with 2‐guanidinebenzimidazole (GBI) (3) the products are 3‐(1H‐benzoimidazol‐2‐yl)‐4‐chloro‐3H‐naphtho[1,2‐d]imidazole‐2,5‐dione (7) and 3‐[3‐(1H‐benzoimidazol‐2‐yl)‐ureido]‐1,4‐dioxo‐1,4‐dihydronaphthalene‐2‐carboxylic acid dimethylamide (8).
Prenylated Benzoic Acids and Phenanthrenes from Liparis Nakaharai
Authors: Kuo Wen‐Lung , Huang Yu‐Ling , Shen Chien‐Chang , Shieh Bor‐Jinn , Chen Chien‐Chih 
Published: May 2015

AbstractChemical investigation on the rhizoma of Liparis nakaharai resulted in the isolation of a new phenanthrene, 7‐hydroxy‐2,3,4‐trimethoxyphenanthrene (1), and three new prenylated benzoic acids, liparacids A (2), B (3), and C (4), together with four known compounds, moscatin, nudol, batatasin III, and 2,5‐dihydroxy‐4‐methoxy‐9,10‐dihydrophenanthrene. The structures of these compounds were elucidated by spectroscopic analysis.
Simultaneous Spectrophotometric Determination of Aluminum and Iron in Micellar Media by Using the H‐Point Standard Addition Method
Authors: Zarei Kobra , Atabati Morteza , Safaei Mahnaz 
Published: May 2015

AbstractA very simple spectrophotometric method for simultaneous determination of aluminum(III) and iron(III) based on formation of their complexes with pyrocatechol violet (PCV) in micellar media, using the H‐point standard addition method (HPSAM), is described. In micellar media, the metal complexes of Al‐PCV and Fe‐PCV are formed very fast. Formation of both of the complexes was complete within 5 min at pH 8.5. The linear ranges for aluminum and iron were 0.05‐2.50 and 0.10‐4.00 μg mL−1, respectively. The relative standard deviation (R.S.D.) for the simultaneous determination 0.40 μg mL−1 of Al(III) and 0.20 μg mL−1 of Fe(III) were 3.24% and 4.22%, respectively. Interference effects of common anions and cations were studied. The method was applied to simultaneous determination of Al(III) and Fe(III) in standard reference material and alloy samples.
FTIR, 1H NMR, ESR, TGA and DTA Analysis of Trithiocarbonates of Captopril and 6‐Mercaptopurine as Their Palladium(II) Chloride Complexes
Authors: Sharma Mukul , Koty Afraim , Srivastava Mamta , Srivastava Ashutosh 
Published: May 2015

AbstractA simple and sensitive spectrophotometric method has been developed for the determination of the antihypertensive drug captopril and anticancer drug 6‐mercaptopurine, in their trithiocarbonate (TTC) form by using Pd(II) chloride as a coloring reagent. Captopril TTC forms a stable dark yellow colored complex with λmax 383 nm, molar absorption coefficient 1.35 × 105 l/mole/cm and a Beer's law range from 0.084‐1.26 ppm. 6‐Mercaptopurine TTC forms a stable deep yellow colored complex with λmax 345 nm, molar absorption coefficient 6.9 × 105 l/mole/cm and a Beer's law range from 0.0319 ppm to 3.519 ppm. The M: L ratio of palladium: TTC complexes were confirmed by Job's method of continuous variance and mole ratio method and was found to be 1:1 for both captopril TTC as well as 6‐mercaptopurine TTC. In addition, on the basis of, FTIR, 1H NMR, ESR and thermal analysis data a plausible structure of mononuclear Pd(II) complex of Captopril TTC and 6‐mercaptopurine TTC has been reported.