bluuebunny/crossref_metadata_2025_split huggingface dataset:
Superiority of tympanic ball electrodes over mastoid needle electrodes for intraoperative monitoring of hearing function
Authors: Krieg Sandro M. , Kempf Lisa , Droese Doris , Rosahl Steffen K. , Meyer Bernhard , Lehmberg Jens 
Published: February 2014

Object
Recording the auditory brainstem response (ABR) is a common method for monitoring the integrity of auditory pathways during surgery in the cerebellopontine angle. Electrocochleography (ECochG) is an alternative means of intraoperative neuromonitoring. In the present study the authors compared the practicability and prognostic significance of these two methods by performing simultaneous recordings in the operating room.

Methods
Between 2006 and 2011, 125 patients (mean age 55 years) underwent surgery in the cerebellopontine angle. Seventy-one percent of the patients presented with a hearing deficit, and 37% had useful hearing but with slight functional impairment. Auditory brainstem response was recorded with a subdermal needle electrode at the mastoid. For ECochG recording, a noninvasive ball electrode was attached to the tympanic membrane. Amplitudes obtained from both ECochG and ABR audiometry were compared and correlated to pre- and postoperative hearing deficits.

Results
Simultaneous intraoperative monitoring via ABR and ECochG was possible in 114 cases (91%). Postoperatively, 42% of patients showed some degree of new hearing deficit, whereas 4% had improvement. The mean amplitudes in ECochG monitoring were significantly higher (0.18 ± 0.04 μV) than the ABR potentials (0.08 ± 0.006 μV; p < 0.05). All waves recorded at the mastoid needle electrode could be recognized in the potentials of the tympanic ball electrode. Hearing outcome correlated more reliably with the relative amplitude changes in Waves III and V in ECochG (III: p = 0.0008, V: p = 0.0015) than in ABR monitoring (III: p = 0.2075, V: p = 0.0398).

Conclusions
Intraoperative monitoring of the auditory system by recording with noninvasive tympanic ball electrodes is more practicable than with subcutaneous needle electrodes at the tragus. Since there is also a reliable correlation between ECochG and clinical outcome, the method can replace common ABR recording during surgery in the cerebellopontine angle.
High-grade spondylolisthesis treated using a modified Bohlman technique: results among multiple surgeons
Authors: Hart Robert A. , Domes Christopher M. , Goodwin Brady , D'Amato Charles R. , Yoo Jung U. , Turker Ronald J. , Halsey Matthew F. 
Published: February 2014

Object
The ideal surgical management of high-grade spondylolisthesis remains unclear. Concerns regarding the original Bohlman transsacral interbody fusion technique with stand-alone autologous fibular strut include late graft fracture and incomplete reduction of lumbosacral kyphosis. The authors' goal was to evaluate the radiographic and surgical outcomes of patients treated for high-grade spondylolisthesis with either transsacral S-1 screws or standard pedicle screw fixation augmenting the Bohlman posterior transsacral interbody fusion technique.

Methods
A retrospective review of patients who underwent fusion for high-grade spondylolisthesis in which a Bohlman oblique posterior interbody fusion augmented with either transsacral or standard pedicle screw fixation was performed by 4 spine surgeons was completed. Estimated blood loss, operating time, perioperative complications, and need for revision surgery were evaluated. Upright pre- and postsurgical lumbar spine radiographs were compared for slip percent and slip angle.

Results
Sixteen patients (12 female and 4 male) with an average age of 29 years (range 9–66 years) were evaluated. The average clinical follow-up was 78 months (range 5–137 months) and the average radiographic follow-up was 48 months (range 5–108 months). Ten L4–S1 and 6 L5–S1 fusions were performed. Five fibular struts and 11 titanium mesh cages were used for interbody fusion. Six patients had isolated transsacral screws placed, with 2 (33%) of the 6 requiring revision surgery for nonunion. No nonunions were observed in patients undergoing spanning pedicle screw fixation augmenting the interbody graft. Six patients experienced perioperative complications including 3 iliac crest site infections, 1 L-5 radiculopathy without motor involvement, 1 deep vein thrombosis, and 1 epidural hematoma requiring irrigation and debridement. The average estimated blood loss and operating times were 763 ml and 360 minutes, respectively. Slip percent improved from an average of 62% to 37% (n = 16; p < 0.01) and slip angle improved from an average of 18° to 8° (n = 16; p < 0.01). No patient experienced L-5 or other motor deficit postoperatively.

Conclusions
The modified Bohlman technique for treatment of high-grade spondylolisthesis has reproducible outcomes among multiple surgeons and results in significant improvements in slip percent and slip angle. Fusion rates were high (14 of 16; 88%), especially with spanning instrumentation augmenting the oblique interbody fusion. Rates of L-5 motor deficit were low in comparison with techniques involving reduction of the anterolisthesis.
Standardizing Scavenger Receptor Nomenclature
Authors: PrabhuDas Mercy , Bowdish Dawn , Drickamer Kurt , Febbraio Maria , Herz Joachim , Kobzik Lester , Krieger Monty , Loike John , Means Terry K. , Moestrup Soren K. , Post Steven , Sawamura Tatsuya , Silverstein Samuel , Wang Xiang-Yang , El Khoury Joseph 
Published: February 2014

Abstract
Scavenger receptors constitute a large family of proteins that are structurally diverse and participate in a wide range of biological functions. These receptors are expressed predominantly by myeloid cells and recognize a variety of ligands, including endogenous and modified host-derived molecules and microbial pathogens. There are currently eight classes of scavenger receptors, many of which have multiple names, leading to inconsistencies and confusion in the literature. To address this problem, a workshop was organized by the U.S. National Institute of Allergy and Infectious Diseases, National Institutes of Health to help develop a clear definition of scavenger receptors and a standardized nomenclature based on that definition. Fifteen experts in the scavenger receptor field attended the workshop and, after extensive discussion, reached a consensus regarding the definition of scavenger receptors and a proposed scavenger receptor nomenclature. Scavenger receptors were defined as cell surface receptors that typically bind multiple ligands and promote the removal of non-self or altered-self targets. They often function by mechanisms that include endocytosis, phagocytosis, adhesion, and signaling that ultimately lead to the elimination of degraded or harmful substances. Based on this definition, nomenclature and classification of these receptors into 10 classes were proposed. The discussion and nomenclature recommendations described in this report only refer to mammalian scavenger receptors. The purpose of this article is to describe the proposed mammalian nomenclature and classification developed at the workshop and to solicit additional feedback from the broader research community.
Mycobacterium celatum infection: Successful treatment with ciprofloxacin and clarithromycin
Authors: Kulawik Joanna Domagała , Safianowska Aleksandra , Walkiewicz Renata , Jaworska Hanna Grubek 
Published: February 2014

Mycobacterium celatum is nontuberculous mycobacterium which is rarely pathogenic in human. We describe the case of M. celatum infection in immunocompetent patient. Caucasian 64-years old female patient was referred to the outpatient service because of pulmonary hemorrhage, cough and fever up to 39oC. She reported previous pulmonary tuberculosis (TB) 3 years ago. At presentation the physical examination was unremarkable. Chest computed tomographic scan showed multifocal bronchiectases and upper lobes consolidations suggestive. Empiric antibiotic therapy with amoxicillin was undertaken. At the same time the consecutive sputum samples were immediately analyzed. Smears of six from eight sputum specimens were positive for acid-fast bacilli by Ziehl-Neelsen staining. Culture from each specimen produced slow-growing mycobacterium, identified as M. celatum by mycolic acid analysis with high performance liquid chromatography. The treatment with clarithromycin and ciprofloxacin was continued for 18 months with clinical improvement. Conclusion- we present the accuracy of microbiological diagnosis of M. celatum in patient with normal immune status, which allowed successful treatment. M. celatum infection was reported in HIV infected patients or with the history of pulmonary TB prior to mycobacterial infection. Also in our patient the TB in anamnesis may indicate “hidden immunodeficiency”.
Imaging systolic and diastolic heart murmurs in hypertrophic cardiomyopathy
Authors: Barison Andrea , Todiere Giancarlo , Masci Pier Giorgio , Aquaro Giovanni D 
Published: February 2014

Muscular obstruction in hypertrophic cardiomyopathy can occur not only in systole, but also in diastole. Here we report a case of hypertrophic cardiomyopathy in a middle-aged lady: echocardiography and cardiovascular magnetic resonance confirmed the diagnosis of hypertrophic cardiomyopathy with significant systolic and diastolic midventricular obstruction, corresponding to the murmurs audible in mid-systole and early-diastole respectively. Moreover, the mid-systolic murmur was clearly distinguishable from the mitral regurgitation murmur, which was audible throughout systole (pan-systolic) and likely related to systolic anterior motion of the mitral chords; similarly, the early-diastolic heart murmur due to diastolic obstruction was better audible at the apex and clearly distinguishable from common diastolic murmurs due to aortic regurgitation. Echocardiography (with Doppler recordings) and magnetic resonance (with turbulence flows at steady state free precession imaging) allowed a detailed visualization of each audible murmur (systolic obstruction, mitral regurgitation, diastolic obstruction). In particular, while systolic obstruction has been extensively studied in hypertrophic cardiomyopathy, only very few reports about diastolic obstruction exist, describing either a normodirected midventricular diastolic obstruction (forward flow) similar to this case or a paradoxical midventricular diastolic obstruction (backward flow) in patients with an apical aneurysm emptying during early diastole into the left ventricular base through a narrow midventricular channel. Whether diastolic obstruction implies worse prognosis or requires specific treatment, deserves further research.
Assessing forest biomass for bioenergy: Operational challenges and cost considerations
Authors: Ralevic P , Ryans M , Cormier D 
Published: February 2014

Sustainability assessments and biomass inventories often neglect the operational challenges involved in the harvesting of forest biomass for bioenergy. Thus, concerns that increasing demands for biomass will lead to greater environmental impacts, particularly on soil productivity, need to be considered from an operations perspective that takes into consideration the technical and cost limitations to biomass recovery. We examine operational forest biomass recovery potential of harvest residue (slash) for three sites located north of Kapuskasing, Ontario. The sites are in the Northern Claybelt, which is in the boreal forest and is comprised primarily of lowland black spruce and upland mixedwoods. Supply flows of harvest residues estimated using the Biomass Opportunity Supply Model (BiOS), developed by FPInnovations – Feric Division are compared to validation data collected from the sites. Costs for the supply flows were also estimated using BiOS. After harvesting limitations and planned retentions (such as wildlife trees) were taken into consideration, 41% (41.2 ovendry tonnes/ha) and 59% (99.1 odt/ha) of total above-ground biomass were estimated to remain on site in two mixedwood blocks, and 25% (25.3 odt/ha) in a black spruce block. Thus, considerable biomass was left on the forest floor, contrary to popular perceptions that bioenergy harvesting will result in a “clearing” or potential “vacuuming” of the forest floor. The delivered cost was $53/odt ($2.86/GJ energy equivalent) and $58/odt ($3.14/GJ) for the two upland sites and $59/odt ($3.19/GJ) for the lowland black spruce site. This is higher than conventional hog fuel costs. Although operational and cost considerations thus limit harvest residue recovery, and although there are a number of operational factors that can minimize environmental impacts on soils and biodiversity, sustainable biomass removal guidelines still need to be implemented on sites sensitive to soil damage and nutrient removal.Key words: biomass, bioenergy, harvest, operations, cost, supply chain, sustainable management, soil nutrients, forest residues, BiOS model, Ontario
Silviculture and planted species interact to influence reforestation success on a Kalmia-dominated site – a 15-year study
Authors: Thiffaul Nelson , Titus Brian D , Moroni Martin T 
Published: February 2014

Successful regeneration following harvesting or natural disturbance is a fundamental prerequisite for sustainable forest management. However, some regenerating stands have poor juvenile growth rates, which compromise sustainable management objectives. In particular, the presence of some ericaceous species that proliferate after forest disturbance, such as Kalmia angustifolia, can slow succession of boreal stands to the point that ecosystem retrogression is induced. We used data from a silvicultural field trial established in central Newfoundland to evaluate how various combinations of silvicultural treatments (trench scarification, herbicide application, fertilization at planting) influenced growth of three conifer species planted on a Kalmia-dominated cutover. Ground-level diameter (GLD), height, diameter at breast height (DBH), and percent Kalmia cover were assessed at the end of 15 growing seasons after planting. We detected several interactions between silvicultural treatments and planted conifer species. Globally, height and estimates of foliar biomass of all conifer species responded positively to scarification. Fifteen-year height in both scarified and unscarified treatments was in the order Picea mariana < Pinus banksiana < Larix laricina. Black spruce and jack pine height increased when Kalmia was controlled with herbicide, but height of tamarack was not. The use of herbicide significantly increased 15-year GLD and volume index of all three conifer species, but only black spruce responded positively to fertilization at planting. Our results confirm that species-specific responses to silvicultural treatments are to be expected when managing Kalmia-dominated sites. Although chemical vegetation management has great silvicultural potential, our results suggest that mechanical site preparation can also be effective in promoting early conifer seedling growth that leads to rapid canopy closure. It is anticipated that canopy closure will lead to exclusion of Kalmia later in the rotation through natural successional pathways. Key words: Kalmia angustifolia, vegetation management, scarification, herbicide, fertilizer, black spruce, jack pine, tamarack
Histoire du Coetus Internationalis Patrum au concile Vatican II
Authors: Roy-Lysencourt Philippe 
Published: February 2014

Le Coetus Internationalis Patrum, dirigé par Mgr Marcel Lefebvre, fut le principal groupe d’opposants au sein du concile Vatican II (1962-1965). Dans cet article, après avoir présenté l’historiographie et les sources permettant d’écrire l’histoire de ce mouvement, l’auteur propose une évaluation de l’organisation, de l’activité et de la stratégie du Coetus tout au long des sessions et intersessions du Concile. Il analyse ensuite l’impact du groupe sur les documents promulgués par Vatican II.
Les actes de l’homme
Authors: Trego Kristell 
Published: February 2014

Qui agit quand j’agis ? Cet article s’intéresse à la réception philosophique de deux versets scripturaires, Jn 15,5 et Ph 2,13, qui, l’un comme l’autre, énoncent une certaine intervention de Dieu dans les actes que l’homme effectue. On prend en premier lieu en considération l’occasionnalisme malebranchiste. On envisage ensuite, au sein du kalâm, le courant asharite, souvent présenté comme « occasionnaliste », et sa réfutation par le philosophe chrétien de l’école de Baghdad Yaḥyâ ibn ‘Adî. On regarde enfin comment la tradition médiévale a, à la suite d’Augustin, concilié nos deux versets avec l’affirmation de la libre volonté humaine.
Reconstructing individual hand models from motion capture data
Authors: Endo Yui , Tada Mitsunori , Mochimaru Masaaki 
Published: February 2014

Abstract
In this paper, we propose a new method of reconstructing the hand models for individuals, which include the link structure models, the homologous skin surface models and the homologous tetrahedral mesh models in a reference posture. As for the link structure model, the local coordinate system related to each link consists of the joint rotation center and the axes of joint rotation, which can be estimated based on the trajectories of optimal markers on the relative skin surface region of the subject obtained from the motion capture system. The skin surface model is defined as a three-dimensional triangular mesh, obtained by deforming a template mesh so as to fit the landmark vertices to the relative marker positions obtained motion capture system. In this process, anatomical dimensions for the subject, manually measured by a caliper, are also used as the deformation constraints.
Qualitative Evaluation of Osteopathic Manipulative Therapy in a Patient With Gastroesophageal Reflux Disease: A Brief Report
Authors: Diniz Leonardo Rios , Nesi Jacson , Curi Ana Christina , Martins Wagner 
Published: February 2014

Abstract

Context: Gastroesophageal reflux disease (GERD) is a chronic condition that affects a growing number of people and is currently among the most common disorders seen in clinical practice.

Objective: To develop a protocol for the management of GERD with osteopathic manipulative therapy (OMTh) applied to the diaphragm and esophagus, and to evaluate the protocol's effectiveness using the quality of life scale (QS-GERD) for the disease.

Methods: In this single-blinded prospective study, an OMTh protocol focusing on the diaphragm and esophagus was applied to a single patient, who had received a diagnosis of GERD 4 years previously. Outcomes were measured using the QS-GERD, which has a total possible score ranging from 0 to 45 (the lower the score, the better the quality of life) and a level of satisfaction from very satisfied to incapacitated. The OMTh protocol was applied at 3 sessions (initial session, second session 1 week after the first, and third session 2 weeks after the second), and the patient completed the QS-GERD 4 times (before the first session, before the third session, and 2 and 4 weeks after the third session).

Results: The OMTh protocol was administered without adverse events, and the patient reported positive outcomes after the third session. The QS-GERD showed a score improvement from 13 of 45 to 4 of 45.

Conclusion: The results in the present report show that OMTh applied to the diaphragm and esophagus may improve symptoms of GERD and should be added to the somatovisceral approach to the care of patients with this condition.
Management of Ionizing Radiation Injuries and Illnesses, Part 1: Physics, Radiation Protection, and Radiation Instrumentation
Authors: Christensen Doran M. , Jenkins Mark S. , Sugarman Stephen L. , Glassman Erik S. 
Published: February 2014

Abstract
Ionizing radiation injuries and illnesses are exceedingly rare; therefore, most physicians have never managed such conditions. When confronted with a possible radiation injury or illness, most physicians must seek specialty consultation. Protection of responders, health care workers, and patients is an absolute priority for the delivery of medical care. Management of ionizing radiation injuries and illnesses, as well as radiation protection, requires a basic understanding of physics. Also, to provide a greater measure of safety when working with radioactive materials, instrumentation for detection and identification of radiation is needed. Because any health care professional could face a radiation emergency, it is imperative that all institutions have emergency response plans in place before an incident occurs. The present article is an introduction to basic physics, ionizing radiation, radiation protection, and radiation instrumentation, and it provides a basis for management of the consequences of a radiologic or nuclear incident.
A Rhodium‐Catalyzed Cascade Cyclization: Direct Synthesis of N‐Substituted Phthalimides from Isocyanates and Benzoic Acids
Authors: Shi Xian‐Ying , Renzetti Andrea , Kundu Soumen , Li Chao‐Jun 
Published: February 2014

AbstractA rhodium(III)‐catalyzed amidation between benzoic acids and isocyanates via direct functionalization of an ortho CH bond followed by intramolecular cyclization is described. This cascade cyclization affords N‐substituted phthalimides in one step in 26–91% yields. The reaction is highly atom‐economical, since no theoretical waste except for water is generated in the reaction.magnified image
A Bis(Triazolecarboxamido) Ligand for Enantio‐ and Regioselective Molybdenum‐Catalyzed Asymmetric Allylic Alkylation Reactions
Authors: Ozkal Erhan , Pericàs Miquel A. 
Published: February 2014

AbstractA modular, enantiomerically pure bis(1H‐1,2,3‐triazole‐4‐carboxamide) has been assembled from N,N′‐[(1R,2R)‐cyclohexane‐1,2‐diyl]dipropiolamide through a copper‐catalyzed azide‐alkyne cycloaddition (CuAAC) reaction and evaluated as a ligand in the molybdenum‐catalyzed asymmetric allylic alkylation (MoAAA) reaction, very high regio‐ and enantioselectivities being recorded.magnified image
Lesion of the dopaminergic nigrostriatal pathway induces trigeminal dynamic mechanical allodynia
Authors: Dieb Wisam , Ouachikh Omar , Durif Franck , Hafidi Aziz 
Published: February 2014

AbstractBackgroundPain constitutes the major non motor syndrome in Parkinson's disease (PD) and includes neuropathic pain; however current drug therapies used to alleviate it have only limited efficacy. This is probably due to poor understanding of the mechanisms underlying it.AimsWe investigated a major class of trigeminal neuropathic pain, dynamic mechanical allodynia (DMA), in a rat model of PD and in which a bilateral 6‐hydroxy dopamine (6‐OHDA) injection was administered to produce a lesion of the nigrostriatal dopaminergic pathway.Results and discussionLesioned animals presented significant DMA in the orofacial area that occurred from 4 days to 5 weeks post‐injury. To investigate a segmental implication in the neuropathic pain induced by dopamine depletion, the expression of the isoform gamma of the protein kinase C (PKCg) and phosphorylated extracellular signal‐regulated kinases 1/2 (pERK1/2) was explored in the medullary dorsal horn (MDH). There was a high increase in PKCg expression in the III and IIi laminae of the MDH of lesioned‐animals compared to shams. pERK1/2 expression was also significantly high in the ipsilateral MDH of lesioned rats in response to non‐noxious tactile stimulus of the orofacial region. Since pERK1/2 is expressed only in response to nociceptive stimuli in the dorsal spinal horn, the current study demonstrates that non‐noxious stimuli evoke allodynic response. Intraperitoneal and intracisternal administrations of bromocriptine, a dopamine 2 receptor (D2R) agonist, significantly decreased DMA compared to control rats injected with saline. These data demonstrate for the first time that nigrostriatal dopaminergic depletion produces trigeminal neuropathic pain that at least involves a segmental mechanism. In addition, bromocriptine was shown to have a remarkable analgesic effect on this neuropathic pain symptom.