bluuebunny/crossref_metadata_2025_split huggingface dataset:
Personal narratives as the highest level of cognitive integration
Authors: Hirsh Jacob B. , Mar Raymond A. , Peterson Jordan B. 
Published: May 2013

AbstractWe suggest that the hierarchical predictive processing account detailed by Clark can be usefully integrated with narrative psychology by situating personal narratives at the top of an individual's knowledge hierarchy. Narrative representations function as high-level generative models that direct our attention and structure our expectations about unfolding events. Implications for integrating scientific and humanistic views of human experience are discussed.
Prediction, explanation, and the role of generative models in language processing
Authors: Farmer Thomas A. , Brown Meredith , Tanenhaus Michael K. 
Published: May 2013

AbstractWe propose, following Clark, that generative models also play a central role in the perception and interpretation of linguistic signals. The data explanation approach provides a rationale for the role of prediction in language processing and unifies a number of phenomena, including multiple-cue integration, adaptation effects, and cortical responses to violations of linguistic expectations.
Attention is more than prediction precision
Authors: Bowman Howard , Filetti Marco , Wyble Brad , Olivers Christian 
Published: May 2013

AbstractA cornerstone of the target article is that, in a predictive coding framework, attention can be modelled by weighting prediction error with a measure of precision. We argue that this is not a complete explanation, especially in the light of ERP (event-related potentials) data showing large evoked responses for frequently presented target stimuli, which thus are predicted.
Bayesian animals sense ecological constraints to predict fitness and organize individually flexible reproductive decisions
Authors: Gowaty Patricia Adair , Hubbell Stephen P. 
Published: May 2013

AbstractA quantitative theory of reproductive decisions (Gowaty & Hubbell 2009) says that individuals use updated priors from constantly changing demographic circumstances to predict their futures to adjust actions flexibly and adaptively. Our ecological/evolutionary models of ultimate causes seem consistent with Clark's ideas and thus suggest an opportunity for a unified proximate and ultimate theory of Bayesian animal brains, senses, and actions.
Perception versus action: The computations may be the same but the direction of fit differs
Authors: Shea Nicholas 
Published: May 2013

AbstractAlthough predictive coding may offer a computational principle that unifies perception and action, states with different directions of fit are involved (with indicative and imperative contents, respectively). Predictive states are adjusted to fit the world in the course of perception, but in the case of action, the corresponding states act as a fixed target towards which the agent adjusts the world. This well-recognised distinction helps side-step some problems discussed in the target article.
Two kinds of theory-laden cognitive processes: Distinguishing intransigence from dogmatism
Authors: Khalil Elias L. 
Published: May 2013

AbstractThe brain is involved in theory-laden cognitive processes. But there are two different theory-laden processes. In cases where the theory is based on facts, more facts can either falsify or confirm a theory. In cases where the theory is about the choice of a benchmark or a standard, more facts can only make a theory either more or less warranted.
Are we predictive engines? Perils, prospects, and the puzzle of the porous perceiver
Authors: Clark Andy 
Published: May 2013

AbstractThe target article sketched and explored a mechanism (action-oriented predictive processing) most plausibly associated with core forms of cortical processing. In assessing the attractions and pitfalls of the proposal we should keep that element distinct from larger, though interlocking, issues concerning the nature of adaptive organization in general.
A giant left ventricular pseudoaneurysm in Behçet's disease: a case report
Authors: Mouine Najat , Bennani Rajae , Amri Rachida 
Published: May 2013

AbstractBehçet's disease is a chronic autoimmune disease with vascular complications that are most frequently manifested as thromboembolism in veins and pseudoaneurysm in arteries. We report the case of a 13-year-old boy admitted for clinical and biological signs of rheumatic fever associated with chest pain. The clinical examination found heart sounds with a discrete systolic murmur of mitral regurgitation. The electrocardiogram showed a microvoltage with diffuse repolarisation disorder. Biologically, he had inflammatory syndrome. Transthoracic echocardiography showed circumferential pericardial effusion with anterosepto-apical hypokinesia of the left ventricle with systolic dysfunction, and a minimal mitral regurgitation. The patient was treated by corticotherapy and antibiotherapy. The outcome was marked by orogenital aphthous ulceration and decreased visual acuity related to intermediate uveitis. The retinal angiography showed a vasculitis. The late appearance of this symptom led to the right diagnosis of Behçet's syndrome. Transthoracic echocardiography showed a hypokinetic dilated cardiomyopathy left ventricular with septo apical and anterior akinesia and severe systolic dysfunction, with a defect of the inferior septal with a collar communicating the left ventricle with a giant pseudo aneurysm. Magnetic resonance imaging showed a giant pseudoaneurysm communicating with the left ventricle. The coronary computed tomography was normal. The patient had undergone surgical treatment for the pseudoaneurysm with good outcomes.
Do Dutch nutrition and dietetics students meet nutritional requirements during education?
Authors: van der Kruk Joke J , Jager-Wittenaar Harriët , Nieweg Roos MB , van der Schans Cees P 
Published: May 2013

AbstractObjectivesTo compare the dietary intakes of Dutch nutrition and dietetics students with the Dutch RDA and the Dutch National Food Consumption Survey (DNFCS), and to assess whether dietary intake changes during education.DesignCross-sectional and longitudinal research (2004–2010).SettingData collection by 7 d dietary record and questionnaire.SubjectsDutch nutrition and dietetics students.ResultsThree hundred and fifty-two first-year and 216 fourth-year students were included. One hundred and thirty-three students in three cohorts were assessed twice. Of first-year students, >80 % met the RDA for all macronutrients. Of these students only 37 % met the RDA for fibre and in 43 % intake of saturated fat was too high. Fourth-year students more often met the RDA for fruits (55 %) and vegetables (74 %) compared with first-year students (32 % and 40 %, respectively). Intake of fruits and vegetables of both first- and fourth-year students was much higher than that of DNFCS participants (where 2 % and 7 %, respectively, met the corresponding RDA). Only <25 % of fourth-year students met the RDA for Fe, Se and vitamin D. In the cohorts, dietary intake for all macronutrients stabilised from the first to the fourth year (>80 %). Intakes of dietary fibre, Ca, Mg, Se, riboflavin, niacin, fruits, vegetables and fish improved significantly during education.ConclusionsDietary intake of nutrition and dietetics students is much better than that of DNFCS participants and improved during education. However, there is still a gap between actual dietary intake and the RDA, especially for Fe, Se and vitamin D.
Disparities in cancer care: Perspectives from the front line
Authors: Miller Patricia A. , Sinding Christina , McGillicuddy Patti , Gould Judy , Fitzpatrick-Lewis Donna , Learn Linda , Wiernikowski Jennifer , Fitch Margaret I. 
Published: May 2013

AbstractObjective:The purpose of this qualitative study was to investigate how frontline healthcare professionals witness and understand disparity in cancer care.Method:Six healthcare providers from a range of care settings, none with < 15 years of frontline experience, engaged with researchers in an iterative process of identifying and reflecting on equity and disparity in cancer care. This knowledge exchange began with formal interviews. Thematic analysis of the interviews form the basis of this article.Results:Participants drew attention to health systems issues, the meaning and experience of discontinuities in care for patients at personal and community levels, and the significance of social supports. Other concerns raised by participants were typical of the literature on healthcare disparities.Significance of results:Providers at the front lines of care offer a rich source of insight into the operation of disparities, pointing to mechanisms rarely identified in traditional quantitative studies. They are also well positioned to advocate for more equitable care at the local level.
Dielectric contrast measurements on biological substances with resonant microwave near-field sensors
Authors: Haase Nora , Jacob Arne F. 
Published: May 2013

Resonant substrate integrated near-field sensors are used for characterization of aqueous solutions at three different frequencies. In addition, Chinese hamster ovary (CHO) cells in a culture medium are characterized with the same sensors. Different concentrations as well as different vital states of cell suspensions are examined. The complex permittivity of the samples is evaluated using a linearized method based on perturbation theory. The permittivity differences between the measured cell suspensions are discussed. The resonant frequencies of the sensors are close to 3, 7, and 11 GHz, respectively.
Amiodarone inhibits the entry and assembly steps of hepatitis C virus life cycle
Authors: Cheng Yuan-Lung , Lan Keng-Hsueh , Lee Wei-Ping , Tseng Szu-Han , Hung Li-Rong , Lin Han-Chieh , Lee Fa-Yauh , Lee Shou-Dong , Lan Keng-Hsin 
Published: May 2013

HCV (hepatitis C virus) infection affects an estimated 180 million people in the world's population. Adverse effects occur frequently with current standard treatment of interferon and ribavirin, while resistance of new direct anti-viral agents, NS3 protease inhibitors, is a major concern because of their single anti-HCV mechanism against the viral factor. New anti-viral agents are needed to resolve the problems. Amiodarone, an anti-arrhythmic drug, has recently been shown to inhibit HCV infection in vitro. The detailed mechanism has yet to be clarified. The aim of the present study was to elucidate the molecular mechanism of the inhibitory effect of amiodarone on HCV life cycle. The effect of amiodarone on HCV life cycle was investigated in Huh-7.5.1 cells with HCVcc (cell culture-derived HCV), HCVpp (HCV pseudoviral particles), sub-genomic replicons, IRES (internal ribosomal entry site)-mediated translation assay, and intracellular and extracellular infectivity assays. The administration of amiodarone appeared to inhibit HCV entry independent of genotypes, which was attributed to the down-regulation of CD81 receptor expression. The inhibitory effect of amiodarone also manifested in the HCV assembly step, via the suppression of MTP (microsomal triacylglycerol transfer protein) activity. Amiodarone revealed no effects on HCV replication and translation. With the host factor-targeting characteristics, amiodarone may be an attractive agent for the treatment of HCV infection.
iFUSE: integrated fusion gene explorer
Authors: Hiltemann Saskia , McClellan Elizabeth A. , van Nijnatten Jos , Horsman Sebastiaan , Palli Ivo , Teles Alves Ines , Hartjes Thomas , Trapman Jan , van der Spek Peter , Jenster Guido , Stubbs Andrew 
Published: May 2013

Abstract
Summary: We present iFUSE (integrated fusion gene explorer), an online visualization tool that provides a fast and informative view of structural variation data and prioritizes those breaks likely representing fusion genes. This application uses calculated break points to determine fusion genes based on the latest annotation for genomic sequence information, and where relevant the structural variation (SV) events are annotated with predicted RNA and protein sequences. iFUSE takes as input a Complete Genomics (CG) junction file, a FusionMap fusion detection report file or a file already analysed and annotated by the iFUSE application on a previous occasion.
Results: We demonstrate the use of iFUSE with case studies from tumour-normal SV detection derived from Complete Genomics whole-genome sequencing results.
Availability: iFUSE is available as a web service at http://ifuse.erasmusmc.nl.
Contact: s.hiltemann@erasmusmc.nl or a.stubbs@erasmusmc.nl
Adaptive reference-free compression of sequence quality scores
Authors: Janin Lilian , Rosone Giovanna , Cox Anthony J. 
Published: May 2013

Abstract
Motivation: Rapid technological progress in DNA sequencing has stimulated interest in compressing the vast datasets that are now routinely produced. Relatively little attention has been paid to compressing the quality scores that are assigned to each sequence, even though these scores may be harder to compress than the sequences themselves. By aggregating a set of reads into a compressed index, we find that the majority of bases can be predicted from the sequence of bases that are adjacent to them and, hence, are likely to be less informative for variant calling or other applications. The quality scores for such bases are aggressively compressed, leaving a relatively small number at full resolution. As our approach relies directly on redundancy present in the reads, it does not need a reference sequence and is, therefore, applicable to data from metagenomics and de novo experiments as well as to re-sequencing data.
Results: We show that a conservative smoothing strategy affecting 75% of the quality scores above Q2 leads to an overall quality score compression of 1 bit per value with a negligible effect on variant calling. A compression of 0.68 bit per quality value is achieved using a more aggressive smoothing strategy, again with a very small effect on variant calling.
Availability: Code to construct the BWT and LCP-array on large genomic data sets is part of the BEETL library, available as a github repository at git@github.com:BEETL/BEETL.git.
Contact: acox@illumina.com
CMAP: Complement Map Database
Authors: Yang Kun , Dinasarapu Ashok R. , Reis Edimara S. , DeAngelis Robert A. , Ricklin Daniel , Subramaniam Shankar , Lambris John D. 
Published: May 2013

Abstract
Summary: The human complement system is increasingly perceived as an intricate protein network of effectors, inhibitors and regulators that drives critical processes in health and disease and extensively communicates with associated physiological pathways ranging from immunity and inflammation to homeostasis and development. A steady stream of experimental data reveals new fascinating connections at a rapid pace; although opening unique opportunities for research discoveries, the comprehensiveness and large diversity of experimental methods, nomenclatures and publication sources renders it highly challenging to keep up with the essential findings. With the Complement Map Database (CMAP), we have created a novel and easily accessible research tool to assist the complement community and scientists from related disciplines in exploring the complement network and discovering new connections.
Availability: http://www.complement.us/cmap.
Contact: lambris@upenn.edu
Supplementary information: Supplementary data are available at Bioinformatics online.
Oil price shocks and stock market behaviour in Nigeria
Authors: Adetunji Babatunde Musibau , Adenikinju Olayinka , Adenikinju Adeola F. 
Published: May 2013

PurposeThe purpose of this study is to investigate the interactive relationships between oil price shocks and the Nigeria stock market.Design/methodology/approachThe paper applied the multivariate vector auto‐regression that employed the generalized impulse response function and the forecast variance decomposition error.FindingsEmpirical evidence reveals that stock market returns exhibit insignificant positive response to oil price shocks but reverts to negative effects after a period of time depending on the nature of the oil price shocks. The results are similar even with the inclusion of other variables. Also, the asymmetric effect of oil price shocks on the Nigerian stock returns indices is not supported by statistical evidences.Originality/valueThis is the first study to examine the dynamic linkages between stock market behaviour and oil price shocks in Nigeria.
Balance‐of‐payments‐constrained growth in a multisectoral framework
Authors: Rocha Gouvêa Raphael , Tadeu Lima Gilberto 
Published: May 2013

PurposeThe aim of this paper is to contribute to the literature on balance‐of‐payments‐constrained growth by providing an innovative empirical evaluation of a disaggregated version of the so‐called Thirlwall's Law derived from a Pasinettian multisectoral framework.Design/methodology/approachAfter estimating sectoral elasticities of exports and imports for a considerable panel dataset of 90 countries over the period 1965‐1999, the authors have performed two empirical exercises. First, they grouped countries together by income level and evaluated a multisectoral balance‐of‐payments‐constrained growth model by analyzing prediction errors and mean absolute deviations. Second, the authors carried out a regression validity test on the results.FindingsThe main findings give support to the validity of the multisectoral version of Thirlwall's Law, providing therefore further understanding of the structural determinants of the uneven international development and guidance for the design of growth‐enhancing national structural policies.Originality/valueThe main value added of this contribution to the existing literature lies in the use of disaggregated trade data in conjunction with modern panel data econometric techniques to obtain empirical estimates on the balance‐of‐payments constraints to long‐run economic growth for an unprecedently large sample of countries.
South American immigrants in the USA
Authors: Medina Carlos , Posso Christian 
Published: May 2013

PurposeThe purpose of this paper is to examine the main factors influencing the decision of migrants from South America (SA) living in the USA to return to their countries of origin. In particular, it is aimed at understanding the role played by higher education in this decision. Although it is not feasible to refer to the tasks performed by immigrants in the USA as determinants in their decision to return to their homelands, it is nonetheless worth verifying whether these tasks are closely related or not to their qualifications.Design/methodology/approachThe program evaluation methodology proposed by Heckman and Robb to correct the “contamination bias” in a program evaluation setting is adopted in this document.FindingsThis exercise shows that the probability of remaining in the USA for those with university degrees or more advanced education levels is 12.6 percent higher than for those with only secondary or lower education. In addition, it is shown that SA immigrants are usually engaged in tasks requiring certain qualifications commensurate with their level of education, although such relationship varies in intensity among migrants from different countries.Research limitations/implicationsThis exercise does not take into account migrants in the USA not included in the US Censuses.Practical implicationsThe results obtained mean that the flight of human capital from SA countries to the USA is being accentuated by the “negative selection” of returnees, and that migrants' qualifications actually determine the complexity of tasks they may perform in the USA.Originality/valueThe paper overcomes the lack of longitudinal data of migrants by implementing a methodology providing new evidence about return migration and brain drain of SA immigrants in the USA. In addition, new data are used to analyze the relationship between education and the complexity of the tasks SA migrants are performing in the USA.
Challenges and developments of micro drill bit for printed circuit board: a review
Authors: Shi Hongyan , Li Hui 
Published: May 2013

PurposeThe purpose of this paper is to present a clear picture of the challenges of micro drill bit and the developments of novel micro‐drill bits for flexible circuit boards, environmental‐friendly printed circuit boards (PCBs), high aspect ratio drill bit and ultra‐small micro drill bit, as well as the developments of geometry design of micro drill bit.Design/methodology/approachThe paper details the developments trend and challenges of micro drill and PCBs first. Then the current research status of novel micro drill bits for flexible circuit boards, environmental‐friendly PCBs, high aspect ratio drill bit, ultra‐small micro drill bit are described. Finally, the developments of geometry design and drilling process are reviewed.FindingsTo achieve excellent performance for drilling flexible PCB, a large helical angle, large flute/land ratio and small web thickness that guarantee the sharp evacuation capability, are adopted in drill bit design. A small helix angle and an appropriate primary face angle are employed for drill bit to process environmental‐friendly printed circuit boards. It is beneficial to implement big helix angle, small primary face angles and small point angles in the design of ultra‐small micro drill bit. An optimum web thickness and step feed should be taken into consideration in high aspect ratio drill bits design.Originality/valueThe paper reviews different solutions of micro drill bits for the state‐of‐the‐art PCB and the developments of geometry design of drill bit for printed circuit boards.
Micro UHMW‐PE column array molded by the utilization of PCB as mold insert
Authors: Liang Xiong , Li Bing , Wu Xiaoyu , Shi Hongyan , Zeng Kun , Wang Yatao 
Published: May 2013

PurposeThe purpose of this paper is to present a method for ultrasonically molding polymer powder in a micro plastic part mold. In the method, a printed circuit board (PCB) in which micro‐hole arrays are drilled is used as a micro cavity insert. With the utilization of ultrasonic vibration, the polymer powder, which is prefilled and compacted in a micro cavity, mutually generates great sliding friction heat so as to be rapidly plasticized and molded.Design/methodology/approachMicro carbide drill bits of which the diameters are 100.0 μm, 150.0 μm and 200.0 μm, respectively, are used for drilling the PCB to form a micro‐hole array insert. Next, two kinds of various ultra‐high molecule weight polyethylene (UHMW‐PE) powder with various grain diameters are directly filled into a charging barrel and a mold cavity with the micro‐hole array insert. Proper process parameters are set on ultrasonic plasticizing and molding equipment so that a molding test can be performed. The melt of UHMW‐PE can be rapidly filled into the cavity. Finally, micro‐column array plastic parts are successfully prepared.FindingsThe micro‐hole array PCB is a mold insert which is quite applicable for the ultrasonic molding of the powder in the mold. When a molding material is the coarse UHMW‐PE powder with the grain diameter of about 350 μm, the diameter replication rates of the micro‐column array plastic parts become good in order with the increased micro‐hole diameter of the PCB. When the fine UHMW‐PE powder with the grain diameter of about 80 μm is adopted, the diameter replication rates of the micro‐column array plastic parts become good in order with the decreased micro‐hole diameter of the PCB.Originality/valueIn this paper, the micro‐column array plastic parts with good replicability are successfully prepared by a technique for ultrasonically plasticizing and molding in the cavity. The technique can be applied to the fields of medical treatment, communication, optics, chemistry and so on, such as biological micro needle arrays, micro biological chips, optical memories, and micro chemical reaction chips.