bluuebunny/crossref_metadata_2025_split huggingface dataset:
Citations of Most Often Cited Economists: Do Scholarly Books Matter More than Quality Journals?
Authors: Jin Jang C. , Choi E. Kwan 
Published: February 2014

AbstractThis paper empirically investigates the determinants of citations based on the publication of the top 100 most often cited economists. The effects of publication age and author fame on subsequent citations are found to be positive and significant. Citations are also significantly affected by popular subfields in economics. However, journal quality measures, such as impact factors, download statistics and top‐4 elite journals, have insignificant effects on citations. In contrast, the citation effect of scholarly books is positive and significant, and its impact is even greater than those of journal quality measures.
Risk factors for miscarriage from a prevention perspective: a nationwide follow‐up study
Authors: Feodor Nilsson S , Andersen PK , Strandberg‐Larsen K , Nybo Andersen A‐M 
Published: February 2014

ObjectiveTo identify modifiable risk factors for miscarriage and to estimate the preventable proportion of miscarriages that could be attributed to these.DesignNationwide observational follow‐up study.SettingDenmark.PopulationNinety‐one thousand four hundred and twenty seven pregnancies included in the Danish National Birth Cohort between 1996 and 2002.MethodsInformation on potentially modifiable risk factors before and during pregnancy was collected by means of computer‐assisted telephone interviews and linkage with Danish registers, ensuring almost complete follow‐up of pregnancy outcome. Modifiable risk factors for miscarriage were identified by multiple Cox regression analysis, which provided the background for our estimations of population attributable fractions. In all, 88 373 pregnancies had full information on all covariates and were included in this analysis.Main outcome measuresMiscarriage before 22 completed weeks of gestation.ResultsThe potentially modifiable pre‐pregnant risk factors associated with increased miscarriage risk were: age of 30 years or more at conception, underweight, and obesity. During pregnancy the modifiable risk factors were: alcohol consumption, lifting of >20 kg daily, and night work. We estimated that 25.2% of the miscarriages might be prevented by reduction of all these risk factors to low risk levels. Modification of risk factors acting before and during pregnancy could lead to prevention of 14.7 and 12.5%, respectively, of the miscarriages. Maternal age at conception and alcohol consumption were the most important risk factors.ConclusionsMiscarriage risk is increased by multiple potentially modifiable risk factors and a considerable proportion of miscarriages may be preventable.
Recent advances in Takayasu arteritis
Authors: Terao Chikashi , Yoshifuji Hajime , Mimori Tsuneyo 
Published: February 2014

AbstractTakayasu arteritis (TAK) is a relatively rare systemic vasculitis mainly affecting the aorta and its large branches. While patients with TAK are more frequently observed in Asian countries, we can find patients with TAK all over the world. This limited number of patients has made it difficult to collect large numbers of patients and perform detailed studies. However, recent progresses have led to the identification of susceptibility genes and novel susceptibility human leukocyte antigen (HLA) alleles as well as accumulation of clues for the pathophysiology of TAK. IL12B was shown to be a susceptibility gene beyond ethnicity. MLX and FCGR2A/3A were shown to be associated with TAK in Japanese and Turkish/American populations, respectively. HLA‐B*52:01 and *67:01 are susceptibility alleles to TAK, and the 171st and 67th amino acid residues of HLA‐B protein are suggested important for TAK susceptibility. HLA‐DQB1/DRB1 is recently reported as an independent susceptibility locus. Although there are no standardized serum markers or composite measures for disease activity of TAK, Japanese and Italian groups showed pentraxin 3 as a novel biomarker for detecting and monitoring patients with TAK. Recently, an Indian group proposed a novel scoring system called ITAS to evaluate disease activity of TAK. Standardization of assessing disease activity would lead to clinical studies with high quality. Several groups reported results of treatment for refractory TAK with biological agents targeting tumor necrosis factor or interleukin‐6R. The recent accumulation of research data should improve understanding of the basic pathophysiology of TAK and lead to better management of patients with TAK.
Esophageal cancer incidence and mortality in China, 2010
Authors: Chen Wanqing , Zheng Rongshou , Zhang Siwei , Zeng Hongmei , Fan Yaguang , Qiao Youlin , Zhou Qinghua 
Published: February 2014

AbstractBackgroundThe National Central Cancer Registry of China (NCCR) is responsible for cancer surveillance. Local cancer registries in each province submit data for annual publication.. The incidence and mortality of esophageal cancer in China in 2010 by age, gender, and area is reported in this article.MethodsThere were data from 145 out of 219 qualified cancer registries. Esophageal cancer cases and deaths (ICD 10 code as C15) were stratified by location, gender, age, and cancer site. The 2000 Chinese census and Segi's population were used for age‐standardized incidence/mortality rates. The rank in all cancer types and cumulative rate were also calculated.ResultsIt was estimated that 287 632 new cases were diagnosed and 208 473 patients died from esophageal cancer in 2010 in China. Esophageal cancer incidence ranked fifth of all cancer types with a rate of 21.88/100 000. Age‐standardized rates by Chinese population (CASR) and World population (WASR) for incidence and mortality were 16.71/100 000 and 16.97/100 000, respectively. The mortality of esophageal cancer ranked fourth in all cancer types with a rate of 15.85/100 000. The CASR and WASR for mortality were 11.95/100 000 and 12.02/100 000, respectively. For both incidence and mortality, the rates of esophageal cancer were much higher in men than that in women, in rural areas than in urban areas, and peaked at age 80–84.ConclusionsEsophageal cancer is still a major cancer type in rural areas of China. Effective prevention and control should be emphasized, including health education, chemoprevention, and early detection in high‐risk groups.
Transitional Paternalism: How Shared Normative Powers Give Rise to the Asymmetry of Adolescent Consent and Refusal
Authors: Manson Neil C. 
Published: February 2014

AbstractIn many jurisdictions, adolescents acquire the right to consent to treatment; but in some cases their refusals – e.g. of life‐saving treatment – may not be respected. This asymmetry of adolescent consent and refusal seems puzzling, even incoherent. The aim here is to offer an original explanation, and a justification, of this asymmetry. Rather than trying to explain the asymmetry in terms of a variable standard of competence – where the adolescent is competent to consent to, but not refuse, certain interventions – the account offered here focuses more closely on the normative power to render actions permissible. Where normative powers are shared they can readily give rise to an asymmetry between consent and refusal. We then turn to why it is justifiable that normative powers be shared in adolescence. Transitional paternalism holds that the acquisition of normative powers by competent adolescents should not be an instant one, achieved in a single step, but that there should be a transitional period where paternalistic protection is rolled back, but not entirely withdrawn until a later date. Transitional paternalism could be implemented without generating the asymmetry between consent and refusal but, it is argued, the asymmetric version of transitional paternalism is to be preferred insofar as it offers a greater respect for the adolescent's decisions than the symmetrical alternative.
High‐molecular‐weight kininogen cleavage correlates with disease states in the bradykinin‐mediated angioedema due to hereditary C1‐inhibitor deficiency
Authors: Suffritti C. , Zanichelli A. , Maggioni L. , Bonanni E. , Cugno M. , Cicardi M. 
Published: February 2014

SummaryBackgroundThe inherited deficiency of C1‐inhibitor (C1‐INH), which can be quantitative (type I) or qualitative (type II), is characterized by recurrent attacks of oedema, and it is known as hereditary angioedema due to C1‐INH deficiency (HAE‐C1‐INH). The frequency of symptoms varies widely among patients and in the same patient during life.ObjectiveTo identify laboratory markers of disease severity in HAE‐C1‐INH patients.MethodsWe studied 162 patients with differently severe HAE‐C1‐INH during remission, 31 HAE‐C1‐INH patients during attacks, and 81 normal controls, evaluating complement parameters, spontaneous plasma kallikrein activity, the capacity of plasma to inhibit exogenous kallikrein activity, and cleavage of high‐molecular‐weight kininogen (HK). Sixty‐five HAE‐C1‐INH patients were screened for mutations in the C1‐INH gene.ResultsAs expected, plasma C1‐INH levels and activity and C4 levels were low in the HAE‐C1‐INH patients. Spontaneous plasma kallikrein activity in patients in remission was higher than in controls (P = 0.001) and increased during acute attacks (P = 0.01), whereas the capacity of inhibiting kallikrein activity was lower in patients in remission than in controls (P = 0.001) and further reduced during attacks (P = 0.001). HAE‐C1‐INH patients in remission had higher levels of cleaved HK than controls (P = 0.001), and these further increased during acute attacks (P = 0.001). Cleaved HK levels were higher in highly symptomatic HAE‐C1‐INH patients than in those with less frequent attacks (P = 0.001). Thirty‐five different mutations in the C1‐INH gene were equally distributed in patients with different attack frequencies.ConclusionsMeasuring plasma levels of cleaved HK may be a sensitive mean of assessing disease severity in HAE‐C1‐INH patients.
Impact of bone graft harvesting techniques on bone formation and graft resorption: a histomorphometric study in the mandibles of minipigs
Authors: Saulacic Nikola , Bosshardt Dieter D. , Jensen Simon S. , Miron Richard J. , Gruber Reinhard , Buser Daniel 
Published: February 2014

AbstractBackgroundHarvesting techniques can affect cellular parameters of autogenous bone grafts in vitro. Whether these differences translate to in vivo bone formation, however, remains unknown.ObjectiveThe purpose of this study was to assess the impact of different harvesting techniques on bone formation and graft resorption in vivo.Material and methodsFour harvesting techniques were used: (i) corticocancellous blocks particulated by a bone mill; (ii) bone scraper; (iii) piezosurgery; and (iv) bone slurry collected from a filter device upon drilling. The grafts were placed into bone defects in the mandibles of 12 minipigs. The animals were sacrificed after 1, 2, 4 and 8 weeks of healing. Histology and histomorphometrical analyses were performed to assess bone formation and graft resorption. An explorative statistical analysis was performed.ResultsThe amount of new bone increased, while the amount of residual bone decreased over time with all harvesting techniques. At all given time points, no significant advantage of any harvesting technique on bone formation was observed. The harvesting technique, however, affected bone formation and the amount of residual graft within the overall healing period. Friedman test revealed an impact of the harvesting technique on residual bone graft after 2 and 4 weeks. At the later time point, post hoc testing showed more newly formed bone in association with bone graft processed by bone mill than harvested by bone scraper and piezosurgery.ConclusionsTransplantation of autogenous bone particles harvested with four techniques in the present model resulted in moderate differences in terms of bone formation and graft resorption.
Extraocular well‐differentiated sebaceous tumors with overlying cutaneous horns: four tumors in three patients
Authors: Jhuang Jie‐Yang , Liao Shu‐Lang , Tsai Jia‐Huei , Chang Hsiao‐Ching , Kuo Kuan‐Ting , Liau Jau‐Yu 
Published: February 2014

BackgroundSebaceous tumors are adnexal neoplasms showing sebocytic differentiation. They range from benign to malignant and are associated with Muir‐Torre syndrome (MTS). Several clinical and histopathological features associated with MTS have been described. Sebaceous tumors with an overlying cutaneous horn are extremely rare.MethodsHematoxylin and eosin‐stained slides were retrospectively reviewed to identify sebaceous tumors with marked hyperkeratosis, a condition that is often associated with cutaneous horns. Clinical correlation and mismatch repair protein immunohistochemical studies were then conducted.ResultsFour tumors from three patients were identified in our archive. Three were classified as sebaceous adenomas, and the fourth was considered as a borderline sebaceous tumor favoring well‐differentiated sebaceous carcinoma. All cases showed loss of expression of mismatch repair proteins (three tumors from two patients exhibited lost expression of MSH2 and MSH6, and the fourth exhibited lost expression of MLH1 and PMS2). Additionally, one patient presented characteristic clinical manifestations of MTS, including multiple sebaceous adenomas and visceral carcinomas.ConclusionsWe suggest that extraocular well‐differentiated sebaceous neoplasms with overlying cutaneous horns may be an indication of underlying mismatch repair protein deficiency and potential MTS. This distinctive morphology might be an exaggerated combination of other features associated with MTS, i.e. keratoacanthoma‐like architecture and extensive holocrine secretion.
Lgbti Discrimination and Parent–Child Relationships: Cross‐Border Mobility of Rainbow Families in the European Union
Authors: Falletti Elena 
Published: February 2014

One of the most critical issues in the landscape of the member states of the European Union is the recognition in other countries of the parent–child relationship within “rainbow” families. The parenthood of partners of same‐sex couples is acknowledged in Spain, Sweden, Denmark, Belgium, and the Netherlands. In other countries laws offer timid and partial protection against discrimination of the children of same‐sex couples. In the majority of countries, however, there is still no legislative provision recognizing and protecting a child's relationship with one of the partners of a same‐sex relationship. This legal fragmentation threatens freedom of movement within the European Union and challenges the principle of discrimination between children only on the basis of the sexual orientation of the partners in the family. By scrutinizing the distortion of the framework of fundamental rights as recognized within the European Union, and by raising the awareness that European citizenship includes a new dimension of individuals' protection, this article will investigate political and juridical issues in relation to the implementation of children's rights and mutual recognition between the states.Keypoint
The innovation of the approach offered in this article lies in the mutual recognition of the forms of protection and on the study of the available case law at the European level. The analysis will be aimed to the fundamental protection of children and to the enforcement of all the measures which are necessary for the full protection of the best interests of the children.
What is Good Parenting? The Perspectives of Different Professionals
Authors: Eve Philippa M. , Byrne Mitchell K. , Gagliardi Cinzia R. 
Published: February 2014

Defining parenting, and good parenting in particular, is a complex task wrought with ambiguities. This creates problems in agreeing on a standard parenting capacity assessment, particularly in relation to strengths as opposed to weaknesses. To address this lack of consensus, the current study explored the convergence and divergence of different professional groups' opinions on good parenting. A mixed‐methods design was employed, with semi‐structured interviews and rating scales administered to 19 professionals with experience in parenting capacity assessments. Data were analyzed using a constructivist grounded theory. The findings suggest that, in general, professionals agree on main themes of good parenting, including (1) insight, (2) willingness and ability, (3) day‐to‐day versus complex/long‐term needs, (4) child's needs before own, (5) fostering attachment, and (6) consistency versus flexibility. Within these six categories, individual differences emerged. Theoretical and practical implications are discussed.Keypoints
Describes the importance of parenting capacity Assessments and the variances in practitioner approaches
Adopts a strengths based approach as an adjunct to the traditional deficits based approach to Parenting capacity assessments
Contextualises the key decision making issues affecting assessors and decision makers in the judicial system
Provides a theoretical model on decision makers opinions regarding good parenting and outlines directions for the development of strengths based assessments as a contribution to child placement decisions
Involvement of platelets in extrahepatic metastasis of hepatocellular carcinoma
Authors: Morimoto Yuki , Nouso Kazuhiro , Wada Nozomu , Takeuchi Yasuto , Kinugasa Hideaki , Miyahara Koji , Yasunaka Tetsuya , Kuwaki Kenji , Onishi Hideki , Ikeda Fusao , Miyake Yasuhiro , Nakamura Shinichiro , Shiraha Hidenori , Takaki Akinobu , Yamamoto Kazuhide 
Published: February 2014

AimRecently, a relationship between platelets and cancer metastasis has been reported. The aim of this study is to elucidate the risk factors for extrahepatic metastasis (EHM), with emphasis on association with platelets in patients, with hepatocellular carcinoma (HCC).MethodsWe examined risk factors for EHM in 1613 consecutive, newly diagnosed HCC patients by logistic regression analysis (case–control study). We also examined the factors by Cox proportional hazard model in a retrospective cohort fashion in 803 patients who received non‐curative treatment for HCC.ResultsIn the case–control study, multivariate analysis revealed that high platelet counts (odds ratio [OR] = 4.84; 95% confidence interval [CI] = 1.29–29.54; P = 0.01), high tumor number and the presence of macroscopic vascular invasion were significantly associated with EHM. In the cohort study, EHM was diagnosed in 71 patients during the study period (mean observation time = 23.3 months). On multivariate analysis, high tumor number, high des‐γ‐carboxyprothrombin (DCP) and Child–Pugh class A were significantly correlated with EHM, and the patients with high platelet counts tended to develop EHM (OR = 1.73; 95% CI = 0.99–3.14; P = 0.055).ConclusionHCC patients with high platelet counts, as well as large numbers of tumors, high serum DCP and Child–Pugh class A, are at risk for EHM.
Resting Energy Expenditure and Systolic Blood Pressure Relationships in Women Across 4.5 Years
Authors: Sriram Neeraj , Hunter Gary R. , Fisher Gordon , Brock David W. 
Published: February 2014

Recent studies have reported a strong association between blood pressure (BP) and resting energy expenditure (REE). However, it is not known whether this relationship persists over time. Therefore, the authors examined the temporal relationship between REE and systolic BP. In addition, the impact of sympathetic tone and anthropometric variables on this relationship was examined. All testing was performed on healthy, overweight African American and European American women aged 25 to 45 years over 4.5 years in the University of Alabama at Birmingham General Clinical Research Center. Repeated‐measures mixed‐models revealed REE as a significant determinant of systolic BP (β=0.0155, P<.0001), independent of catecholamines, leg fat, visceral fat, fat‐free mass, fat mass, height, relative skeletal muscle index, and resting heart rate. Observations that REE is predictive of systolic BP across 4.5 years support previous findings that REE may potentially mediate resting BP, independent of anthropometric variables and a marker for sympathetic tone.
Changes in Physical and Dielectrical Properties of Carp Meat (Cyprinus Carpio) during Cold Storage
Authors: Ochrem Andrzej Stanisław , Zapletal Piotr , Maj Dorota , Gil Zygmunt , Żychlińska‐Buczek Justyna 
Published: February 2014

AbstractResearch carried out on gutted and ungutted carps showed changes in physical and dielectrical properties during storage under refrigerated conditions. During the research, quality index scheme for carp was developed. In the conducted experiment, statistically significant (P ≤ 0.05) differences in pH values between the gutted and ungutted fish, and between successive days in both groups, were not observed. Within 10 days of storage of the carps in refrigerated conditions, the Torrymeter values were steadily decreasing. Based on the results, the equations were set. Conductivity and electrical resistance were significantly correlated with Torrymeter readings on the head, tail and belly.Practical ApplicationsThis work addresses the evaluation of the freshness of a carp (Cyprinus carpio) meat. Simple, quick and accurate methods have been proposed. Consumers and traders were able to monitor the quality of fish fillets during refrigeration storage using Torrymeter and QIM (quality index method), measurement of electrical resistance.
To Say or not to Say: Dyadic Ambivalence over Emotional Expression and Its Associations with Pain, Sexuality, and Distress in Couples Coping with Provoked Vestibulodynia
Authors: Awada Nayla , Bergeron Sophie , Steben Marc , Hainault Victoria-Ann , McDuff Pierre 
Published: February 2014

Abstract

Introduction
Provoked vestibulodynia (PVD) is a highly prevalent and taxing female genital pain condition. Despite the intimate nature of this pain and the fact that affective factors such as anxiety have been shown to modulate its manifestations, no study has yet explored the emotional regulation of couples in which the woman suffers from PVD.

Aim
Ambivalence over emotional expression (AEE) is an emotional regulation variable that quantifies the extent to which a person is comfortable with the way she or he expresses emotions. We examined whether the dyadic AEE of couples in which the woman suffers from PVD was differentially associated with women's pain and couples' psychological, sexual, and relational functioning.

Methods
Couples (N = 254), in which the woman suffered from PVD, completed the AEE questionnaire. A couple typology of dyadic AEE was created.

Main Outcome Measures
Dependent measures for both members of the couple were the global measure of sexual satisfaction scale, the Beck depression inventory II, and the revised dyadic adjustment scale. The female sexual function index and the sexual history form were used to assess the sexual function of women and men, respectively. Women also completed the pain rating index of the McGill pain questionnaire.

Results
Couples, in which both partners were considered low on AEE, had the highest scores on sexual satisfaction (P = 0.02) and function (P &lt; 0.01), the lowest depression scores (P &lt; 0.01), and the best dyadic adjustment (P = 0.02). No difference in pain intensity was found between couples.

Conclusions
Findings suggest that, for couples in which the woman suffers from PVD, an emotional regulation that is low in ambivalence in both partners is associated with better psychological, sexual, and relational outcomes. Results indicate that emotional regulation may be important to consider in the assessment and treatment of couples coping with PVD.