bluuebunny/crossref_metadata_2025_split huggingface dataset:
Plasma levels of active Von Willebrand factor are increased in patients with first ST-segment elevation myocardial infarction: A multicenter and multiethnic study
Authors: Rutten B , Maseri A , Cianflone D , Laricchia A , Cristell NA , Durante A , Spartera M , Ancona F , Limite L , Hu D , Li H , Uren NG , de Groot PG , Mannucci PM , Roest M 
Published: May 2014

Aims: Von Willebrand factor (VWF), a key player in hemostasis and thrombosis, is released from endothelial cells during inflammation. Upon release, VWF is processed by ADAMTS13 into an inactive conformation. The aim of our study was to investigate whether plasma levels of active VWF, total VWF, ADAMTS13, osteoprotegerin (OPG) and the ratios between VWF and ADAMTS13 are risk factors for first ST-segment elevation myocardial infarction (STEMI). Methods and results: We assessed 1026 patients with confirmed first STEMI and 652 control subjects from China, Italy and Scotland, within six hours after their cardiovascular event. Median plasma levels of total VWF, active VWF, OPG and ratios VWF/ADAMTS13 were increased, while plasma levels of ADAMTS13 were decreased in patients compared to controls. The odds ratio (OR) of STEMI in patients with high plasma levels of active VWF was 2.3 (interquartile range (IQR): 1.8–2.9), total VWF was 1.8 (1.4–2.3), ADAMTS13 was 0.6 (05–0.8), OPG was 1.6 (1.2–2.0) and high VWF/ADAMTS13 ratios was 1.5 (1.2–2.0). The OR for total VWF, active VWF and ratios VWF/ADAMTS13 remained significant after adjustment for established risk factors, medical treatment, C-reactive protein, total VWF, ADAMTS13 and OPG. When we adjusted for levels of active VWF, the significance of the OR for VWF and ratios VWF/ADAMTS13 disappeared while the OR for active VWF remained significant. Conclusions: We found evidence that plasma levels of active VWF are an independent risk factor for first STEMI in patients from three different ethnic groups. Our findings confirm the presence of VWF abnormalities in patients with STEMI and may be used to develop new therapeutic approaches.
Long term follow up and retrospective study on 533 gastric cancer cases
Authors: Zeng Wei-Juan , Hu Wen-Qin , Wang Lin-Wei , Yan Shu-Guang , Li Jian-Ding , Zhao Hao-Liang , Peng Chun-Wei , Yang Gui-Fang , Li Yan 
Published: May 2014

Abstract

Background
Gastric cancer (GC) is the third leading cause of cancer death in China and the outcome of GC patients is poor. The aim of the research is to study the prognostic factors of gastric cancer patients who had curative intent or palliative resection, completed clinical database and follow-up.

Methods
This retrospective study analyzed 533 GC patients from three tertiary referral teaching hospitals from January 2004 to December 2010 who had curative intent or palliative resection, complete clinical database and follow-up information. The GC-specific overall survival (OS) status was determined by the Kaplan-Meier method, and univariate analysis was conducted to identify possible factors for survival. Multivariate analysis using the Cox proportional hazard model and a forward regression procedure was conducted to define independent prognostic factors.

Results
By the last follow-up, the median follow-up time of 533 GC patients was 38.6 mo (range 6.9-100.9 mo), and the median GC-specific OS was 25.3 mo (95% CI: 23.1-27.4 mo). The estimated 1-, 2-, 3- and 5-year GC-specific OS rates were 78.4%, 61.4%, 53.3% and 48.4%, respectively. Univariate analysis identified the following prognostic factors: hospital, age, gender, cancer site, surgery type, resection type, other organ resection, HIPEC, LN status, tumor invasion, distant metastases, TNM stage, postoperative SAE, systemic chemotherapy and IP chemotherapy. In multivariate analysis, seven factors were identified as independent prognostic factors for long term survival, including resection type, HIPEC, LN status, tumor invasion, distant metastases, postoperative SAE and systemic chemotherapy.

Conclusions
Resection type, HIPEC, postoperative SAE and systemic chemotherapy are four independent prognostic factors that could be intervened for GC patients for improving survival.
Spatial primitives and knowledge organization in planning and architecture: some experimental notes
Authors: Borri Dino , Camarda Domenico , Stufano Rossella 
Published: May 2014

Abstract
Cities and territories share structural references to a common environmental ontology, in which space perception and representation play a major role. Many human abilities deal with space management, whose ontology can be useful in building intelligent machines in which space conceptualization plays a fundamental role. Space organizing is an important human ability, in which sensorial and mental abilities intriguingly interact. The analysis of human intelligent abilities in this functional perspective helps in shedding light on aspects otherwise erroneously given for granted. Human agents conceptualize, design and organize spaces for human organizations, for example in architectural design, by using numerous routine and non-routine cognitive processes often analysed. Yet automated reasoning/design agents still provide only bad copies of human performances . Here, creativity is postulated as a non-routine sophisticated human cognitive function, a conscious and intentional process for redefining agents’ situations in the world in new ways. Even if the concept of creativity remains controversial, an increasing number of cognitive scientists considers creativity as a specific part of the ordinary cognitive equipment of the human agent, to be used in certain situations, not confined to a limited set of exceptional human agents .In this context, we assume that it is worthwhile adding spatial domain to the other domains of creativity studied in cognitive science. We also assume that space understanding and space organizing can be fruitfully analyzed and modelled by paying attention to both routine and non-routine (creative) cognitive functions. The domain of civil architecture is a relevant domain of spatial knowledge and action and of course of spatial organization. In it, aesthetics and art, based on creativity mechanisms, play an important role. Studies on architectural creativity based on self-biographies by leading architects (who usually motivate their designs with memories of other designs or spaces, or architectures, experienced by them in the past) prove that spatial memory has primary importance on creativity.
The paper carries out an introductory discussion on such issues, by analysing the case studies of single-agent and multi-agent spatial organizations under the level of spatial design. The paper explores possible modelling approaches and system architectures supporting cognition-oriented activities in spatial organizations.
Nature is (a) mine: conceptions of nature in the Dutch ecogenomics community
Authors: Van der Hout Sanne 
Published: May 2014

AbstractEvery field of science, but especially biology, contains particular conceptions of nature. These conceptions are not merely epistemological or ontological, but also have normative dimensions; they provide anethos, a framework for moral orientation. These normative dimensions, whilst often remaining ‘hidden’ and inarticulate, influence the way in which biologists practice their profession. In this paper, I explore what happens when different versions of these implicit normative frameworks collide. To do so, I will focus on a case study from the field of ecological genomics as it has evolved in one particular country, namely the Netherlands. During an important inaugural meeting, the director of one of the most sizeable Dutch ecogenomics centres gave a presentation in which he introduced the term ‘nature mining’. Part of the audience immediately embraced the term, but others were very reluctant. This mixed response is generally explained as a culmination of growing tension about the future direction of the field: due to new funding demands, a shift had occurred from fundamental research to research more interested in ‘valorisation’.In addition to this current interpretation, I will argue that the turmoil caused by the use of the term ‘nature mining’ also reveals a more fundamental difference between the various parties involved in the Dutch ecogenomics community. This term is part of a vocabulary that emphasises the beneficial ‘goods’ produced by nature. Whereas part of the audience saw no harm in this commodification of nature, others had difficulties with the reduction of nature to a reservoir to be exploited using the latest technologies. I will conclude by arguing that, although at present, the core of Dutch ecogenomics research reflects a more or less instrumental attitude towards nature, the field also harbours other interpretations of nature as a significant and meaningful order. For instance, ecogenomics might further develop the image of land as a ‘collective organism’, as proposed by Aldo Leopold.
Straightforward Synthesis of Levulinic Acid Ester from Lignocellulosic Biomass Resources
Authors: Nemoto Koji , Tominaga Ken-ichi , Sato Kazuhiko 
Published: May 2014

Abstract
Use of a combination of Brønsted acid and Lewis acid directly afforded methyl levulinate in good yield from various raw lignocellulosic biomass resources.
Validity of Medical Chart Weights and Heights for Obese Pregnant Women
Authors: Leo Michael C. , Lindberg Nangel M. , Vesco Kimberly K. , Stevens Victor J. 
Published: May 2014

Objective: To determine the validity of adult body weights and heights recorded in
electronic medical records (EMRs) in the course of routine medical care.Background: EMRs
allow the potential use of data collected in the course of routine medical care for a
variety of research applications in many fields including epidemiology and comparative
effectiveness studies. However, researchers familiar with carefully controlled
measurement protocols typically used in clinical trials may question the validity of
data collected in the course of routine clinical care.Methods: Weights and heights
collected during a research project that focused on weight gain during pregnancy were
compared to weight and height measurements coincidently recorded in the research
participant’s medical records. For weight measures (N=102), data recorded within ±14
days were compared, and for height measures (N=114), data recorded within ±5 years were
compared. We assessed agreement between medical and research measurements using the
concordance and intraclass correlation coefficients, and Bland and Altman’s limits of
agreement.Findings: The mean research and medical record weight measurements were 99.3
kg and 99.2 kg, respectively. The concordance and intraclass correlation coefficients
for weight had similar estimates of .999 and 95 percent confidence intervals [.998,
.999]. The 95 percent limits of agreement were -1.5 kg and +1.7 kg. The mean research
and medical height measurements were 1.646 m and 1.654 m, respectively, and the
concordance and intraclass correlation coefficients for height were .941 and .942,
respectively. The 95 percent limits of agreement were -.031 m and +.047
m.Conclusions: For pregnant women, body weights documented in the medical record are
exchangeable with body weights recorded in a research setting. Height measurements
recorded in the medical records were not in as close agreement as weights, but
concordance between medical record and research height measurements are high enough to
allow them to be used epidemiological and comparative effectiveness research.
Evaluation of the Sebia CAPILLARYS 2 Flex Piercing for the Measurement of HbA1c on Venous and Capillary Blood Samples
Authors: Heylen Olivier , Van Neyghem Stefaan , Exterbille Sandra , Wehlou Charline , Gorus Frans , Weets Ilse 
Published: May 2014

Abstract

Objectives:
We evaluated the Sebia CAPILLARYS 2 Flex Piercing (Cap 2FP; Sebia, Lisses, France) for measurement of hemoglobin A1c (HbA1c) on venous and capillary blood samples.

Methods:
We analyzed whole-blood samples and control materials with the Cap 2FP and Tosoh G8 (Tosoh Corporation, Tokyo, Japan). Capillary blood samples were analyzed on the Cap 2FP on different storage conditions and were compared with venous samples.

Results:
Both instruments achieved total imprecision of less than 2.5% (International Federation of Clinical Chemistry units). Bias was 1 mmol/mol or less and 4 mmol/mol or less for the Cap 2FP and Tosoh G8, respectively. The Cap 2FP was not prone to common interferences. The Tosoh G8 showed significant bias only for carbamylated hemoglobin and did not completely separate hemoglobin D and hemoglobin E. On the Cap 2FP, storage of capillary blood at room temperature showed no significant bias. There was good agreement with venous blood.

Conclusions:
The Cap 2FP and Tosoh G8 perform excellently for HbA1c determination. Capillary blood can be analyzed on the Cap 2FP as an acceptable alternative to venous blood and point-of-care testing. Home collection and central analysis of capillary blood could contribute to a reduction of health care costs without reducing quality of HbA1c determination.
‘They point guns for money, we run the country!’: Provincial modernities in Hatke cinema
Authors: Paul Arunima 
Published: May 2014

Abstract
Much recent scholarship on post-liberalization Indian cinema has explored the ways in which its productions have participated in or pushed back against the ideological project of neo-liberal transformation. Significantly, both kinds of critical endeavours have focused on genres depicting the metropolis and its rich cinematic figures (the new creative hero, the psychotic hero, the tapori, the metrosexual) as the locus of the elaboration and exploration of modernity. Recent ‘hatke’ cinema or the growing body of films addressing the domestic cosmopolitan, which are distinctive (or ‘hatke’) in their formal and thematic innovativeness, realism and indie-style; has also been the subject of these critical enquiries. This article examines two films from within the landscape of hatke cinema that depict northern Indian provincial youth: Tigmanshu Dhulia’s Haasil (2003) and Kabeer Kaushik’s Sehar (2005). Popular and critical discussions of these films have located their ‘hatke’ quotient in their ‘deglam’ depictions of university politics, student politicians, hostel cultures and provincial youth’s sense of disaffection. In this article I argue that the provincial youth-film troubles binaristic notions of the metropolitan as the site of India’s global modernity and the provincial hinterland as entrapped by age-old structures of caste and feudalism. Through its exploration of caste-masculinities in the mundane spaces of a provincial small-town (rather than the aspirational horizons of Indian or global metropolises), the genre registers what I call ‘provincial modernities’ as a complex of the intertwined colonial, postcolonial and neo-liberal histories of the developmental project and power. In these films, the figure of the youth political-entrepreneur through his occupation of the discrete spaces of the provincial university campus (corridors, classrooms, hostels), and his subsequent infiltration of economically burgeoning sections of the city (railway contracting, real estate, telecommunications), illuminates a long provincial history of the bourgeois nation-state, crony capitalism and subsequent transformations wrought by economic liberalization and the democratization of caste. In doing so, I argue, the films posit the provincial as another site of impact as well as formulation of contemporary modernity and its inequities.
From Devdas to Dev.D: Melodrama, mourning and nostalgia
Authors: Banerjee Koel 
Published: May 2014

Abstract
This article explores the trajectory of Indian cinematic melodrama as the site of cinematic exhibition shifts from the single screen theatre to the multiplex through an analysis of the archetype of the self-annihilating protagonist, Devdas. It examines, in particular, the three cinematic retellings of Sarat Chandra Chatterjee’s novel Devdas (1917) – Devdas (Roy, 1955), Devdas (Bhansali, 2002) and Dev.D (Kashyap, 2009). Arguing that the melodramatic impulse to return to a ‘space of innocence’ makes the modality of melodrama essentially nostalgic, it explores the different kinds of nostalgia at play in the three retellings. The different relationship each instance of nostalgia has to time, it argues, is intrinsically connected to the different valences of loss that inform the different kinds of mourning at work in these films. Finally, the article attempts to answer if melodrama remains a valid lens through which one can continue to view cinema in the age of the multiplex.
New additions to the benthic marine flora of Kongsfjorden, western Svalbard, and comparison between 1996/1998 and 2012/2013
Authors: Fredriksen Stein , Bartsch Inka , Wiencke Christian 
Published: May 2014

Abstract
We did a survey on macroalgal diversity along a transect off Hansneset (78°39′N, 11°57′E), Kongsfjorden, western Svalbard, between 0- and >15-m depths in 2012/2013. One major intention was to compare our data to a similar study performed in 1996/1998 at the same site and to document possible changes. We identified 58 species of macroalgae, 12 Chlorophyta, 31 Phaeophyceae, and 15 Rhodophyta. One species (Sphacelorbus nanus) is a new record for Svalbard. Fourteen species are new records for the Kongsfjorden area. Fertile tetrasporophytes of Turnerella pennyi (Cruoria phase) and the microscopic Chlorochytrium stage of Spongomorpha aeruginosa are also recorded for the first time from Svalbard. An increase from 20 to 45 species in the littoral in 2012/2013 compared with 1996/1998 was recorded. This study increases the total macroalgal species diversity of Kongsfjorden to 76. While 62 species were found in 1996/1998 and 58 in 2012/2013, only 42 were common to both investigations. We have made some taxonomic annotations to 20 species/genera. Strikingly, we did not find again some red algae, such as Hildenbrandia rubra, Palmaria palmata, Polysiphonia spp., or Scagelia pylaisaei, that had been recorded in 1996/1998. Possible reasons for the changes based on recent knowledge from Kongsfjorden are discussed.
Large deviation for multivalued backward stochastic differential
equations
Authors: N'Zi Modeste , Dakaou Ibrahim 
Published: May 2014

Abstract.
We consider a multivalued forward-backward stochastic differential
equation where the diffusion coefficient of the forward equation
is perturbed by a small parameter

ε
>
0

${\varepsilon &gt; 0}$

. We prove
that, as ε goes to 0, the solution of the backward
equation converges to the solution of a deterministic backward
equation and satisfies a Freidlin–Wentzell type large deviation
principle.
Reactivation of antecedents by overt vs null pronouns: Evidence from Persian
Authors: Keshtiari Niloofar , Vasishth Shravan 
Published: May 2014

In Persian, a construction exists in which a gap can optionally be replaced by an overt pronoun. A self-paced reading study (110 participants) suggests that the overt pronoun results in deeper encoding (higher activation) of the antecedent noun, presumably because of richer retrieval cue specifications during antecedent retrieval at the pronoun; this higher activation has the consequence that the antecedent is easier to retrieve at a subsequent stage. This provides new evidence for reactivation effects of the type assumed in the cue-based retrieval model of parsing (Lewis and Vasishth, 2005), and shows that dependency resolution is not simply a matter of connecting two co-dependents; the retrieval cue specification has a differential impact on processing.
Hydrothermal synthesis and characterization of the eulytite phase of bismuth germanium oxide powders
Authors: Boyle Timothy J. , Sivonxay Eric , Yang Pin , Rodriguez Mark A. , Hernandez-Sanchez Bernadette A. , Bell Nelson S. , Velazquez Andrew , Kaehr Bryan , Bencomo Marlene , Griego James J.M. , Doty Patrick 
Published: May 2014

Abstract
GOAPhAR: An Integrative Discovery Tool for Annotation, Pathway Analysis
Authors: Sachin Mathur , Mahesh Visvanathan , Stan Svojanovsky , Byunggil Yoo , Adagarla B. Srinivas , Gerald H. Lushington , Peter G. Smith 
Published: May 2014

We have developed the web based tool GOAPhAR (Gene Ontology, Annotations and Pathways for Array Research), that integrates information from disparate sources regarding gene annotations, protein annotations, identifiers associated with probe sets, functional pathways, protein interactions, Gene Ontology, publicly available microarray datasets and tools for statistically validating clusters in microarray data. Genes of interest can be input as Affymetrix probe identifiers, Genbank, or Unigene identifiers for human, mouse or rat genomes. Results are provided in a user friendly interface with hyperlinks to the sources of information.
The tool is freely available at http://bioinformatics.kumc.edu/goaphar/.
‘Western Education is Sinful’: Boko Haram and the Abduction of Chibok Schoolgirls
Authors: Peters Michael A. 
Published: May 2014

Western education is a sin! What does that mean to you? It's the definition of ‘Boko Haram’, the Islamist group of which I, Abul Qaga, am the spokesman. The group, founded in 2002 by Muhammad Yusuf in Maiduguri, capital of Borno State in north-eastern Nigeria, has been making a name for itself in Africa and throughout the world. Its original name in Arabic is Jama'atu Ahlis Sunna Lidda'awati Wal-Jihad (the Congregation of the People of Tradition for Proselytism and Jihad). We do not beat around the bush. Our goal? The application of Sharia law throughout Nigeria. How do we go about it? Through kidnappings, bombings and suicide attacks aimed at the United Nations, churches and symbols of the federal government such as police stations. ( https://en.rsf.org/predator-the-islamist-group-boko-haram44536.html )
Update on Safety Issues Related to Antihyperglycemic Therapy
Authors: Carpio Gandahari Rosa A. , Fonseca Vivian A. 
Published: May 2014

In BriefThe American Diabetes Association emphasizes the importance of individualized patient care in the management of diabetes. One of the important considerations in choosing an antihyperglycemic agent is its side-effect and safety profile. This article reviews the common and clinically significant side effects of each class of agents, including ways to prevent and overcome their occurrence.
Simple proofs of some generalizations of the Wilson’s theorem
Authors: Górowski Jan , Łomnicki Adam 
Published: May 2014

Abstract
In this paper a remarkable simple proof of the Gauss’s generalization of the Wilson’s theorem is given. The proof is based on properties of a subgroup generated by element of order 2 of a finite abelian group. Some conditions equivalent to the cyclicity of (Φ(n), ·n), where n > 2 is an integer are presented, in particular, a condition for the existence of the unique element of order 2 in such a group.