bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prioritizing threats to improve conservation strategy for the tiger Panthera tigris in the Sundarbans Reserve Forest of Bangladesh
Authors: Aziz Abdul , Barlow Adam C. D. , Greenwood Christina C. , Islam Anwarul 
Published: July 2013

AbstractTigers Panthera tigris face a wide and complex array of threats. Given limited time and resources it is essential to direct conservation actions based on the relative importance of each threat. The Sundarbans Reserve Forest is the last stronghold of tigers in Bangladesh and supports one of the largest populations of tigers in the world. As in other tiger landscapes, the threats faced by the tigers have yet to be assessed. This study follows an approach developed by The Nature Conservancy to identify and prioritize threats and set a time-frame for their reduction. We identified a total of 23 threats; four were linked to tigers, two to prey and 17 to habitat. Of the identified threats, the highest ranked included poaching of tigers, poaching of prey, sea-level rise, upstream water extraction/divergence, wood collection, fishing, and harvesting of other aquatic resources. All threats were then scheduled for reduction, based on the rank and current information base for each threat and the likely time-frame for implementing potential solutions. This study demonstrates how the application of a prioritization framework can greatly improve the focus and likelihood of success of any species- or ecosystem-based conservation programme.
Toward a second-person neuroscience
Authors: Schilbach Leonhard , Timmermans Bert , Reddy Vasudevi , Costall Alan , Bente Gary , Schlicht Tobias , Vogeley Kai 
Published: July 2013

AbstractIn spite of the remarkable progress made in the burgeoning field of social neuroscience, the neural mechanisms that underlie social encounters are only beginning to be studied and could – paradoxically – be seen as representing the “dark matter” of social neuroscience. Recent conceptual and empirical developments consistently indicate the need for investigations that allow the study of real-time social encounters in a truly interactive manner. This suggestion is based on the premise that social cognition is fundamentally different when we are in interaction with others rather than merely observing them. In this article, we outline the theoretical conception of a second-person approach to other minds and review evidence from neuroimaging, psychophysiological studies, and related fields to argue for the development of a second-person neuroscience, which will help neuroscience to really “go social”; this may also be relevant for our understanding of psychiatric disorders construed as disorders of social cognition.
Towards a diagrammatic classification
Authors: Giardino Valeria 
Published: July 2013

AbstractIn this article I present and discuss some criteria to provide a diagrammatic classification. Such a classification is of use for exploring in detail the domain of diagrammatic reasoning. Diagrams can be classified in terms of the use we make of them—staticordynamic—and of the correspondence between their space and the space of the data they are intended to represent. The investigation is not guided by the opposition visual vs. non-visual, but by the idea that there is a continuous interaction between diagrams and language. Diagrammatic reasoning is characterized by a duality, since it refers both to an object, the diagram, having its spatial characteristics, and to a subject, the user, who interprets them. A particular place in the classification is occupied byconstructional diagrams, which exhibit for the user instructions for the application of some procedures.
AN EYE FOR WORDS
Authors: Godfroid Aline , Boers Frank , Housen Alex 
Published: July 2013

This eye-tracking study tests the hypothesis that more attention leads to more learning, following claims that attention to new language elements in the input results in their initial representation in long-term memory (i.e., intake; Robinson, 2003; Schmidt, 1990, 2001).Twenty-eight advanced learners of English read English texts that contained 12 targets for incidental word learning. The target was a known word (control condition), a matched pseudoword, or that pseudoword preceded or followed by the known word (with the latter being a cue to the pseudoword’s meaning). Participants’ eye-fixation durations on the targets during reading served as a measure of the amount of attention paid (see Rayner, 2009).Results indicate that participants spent more time processing the unknown pseudowords than their matched controls. The longer participants looked at a pseudoword during reading, the more likely they were to recognize that word in an unannounced vocabulary posttest. Finally, the known, appositive cues were fixated longer when they followed the pseudowords than when they preceded them; however, their presence did not lead to higher retention of the pseudowords.We discuss how eye-tracking may add to existing methodologies for studying attention and noticing (Schmidt, 1990) in SLA.
An analysis of functional modeling approaches across disciplines
Authors: Eisenbart Boris , Gericke Kilian , Blessing Luciënne 
Published: July 2013

AbstractAuthors across disciplines propose functional modeling as part of systematic design approaches, in order to support and guide designers during conceptual design. The presented research aims at contributing to a better understanding of the diverse functional modeling approaches proposed across disciplines. The article presents a literature review of 41 modeling approaches from a variety of disciplines. The analysis focuses on what is addressed by functional modeling at which point in the proposed conceptual design process (i.e., in which sequence). The gained insights lead to the identification of specific needs and opportunities, which could support the development of an integrated functional modeling approach. The findings suggest that there is no such shared sequence for functional modeling across disciplines. However, a shared functional modeling perspective has been identified across all reviewed disciplines, which could serve as a common basis for the development of an integrated functional modeling approach.
Vulnerability to depression: A moderated mediation model of the roles of child maltreatment, peer victimization, and serotonin transporter linked polymorphic region genetic variation among children from low socioeconomic status backgrounds
Authors: Banny Adrienne M. , Cicchetti Dante , Rogosch Fred A. , Oshri Assaf , Crick Nicki R. 
Published: July 2013

AbstractChild maltreatment, peer victimization, and a polymorphism of the serotonin transporter gene (5-HTTLPR) were examined as predictors of depressive symptomatology. Children (Mage = 11.26,SD= 1.65), including 156 maltreated and 145 nonmaltreated children from comparable low socioeconomic backgrounds, provided DNA samples and self-reports of relational peer victimization, overt peer victimization, and depressive symptoms. Path analysis showed that relational and overt victimization mediated the association between child maltreatment and depressive symptoms. Bootstrapping procedures were used to test moderated mediation and demonstrated that genotype moderated the indirect effects of relational and overt victimization on child depressive symptoms, such that victimized children with the long/long variation were at an increased risk for depressive symptoms compared to victimized children carrying a short allele. Results highlight the utility of examining process models that incorporate biological and psychological factors contributing to the development of depressive symptomatology and provide direction toward understanding and promoting resilience among high-risk youth from a multiple levels of analysis approach.
Interests in high-functioning autism are more intense, interfering, and idiosyncratic than those in neurotypical development
Authors: Anthony Laura Gutermuth , Kenworthy Lauren , Yerys Benjamin E. , Jankowski Kathryn F. , James Joette D. , Harms Madeline B. , Martin Alex , Wallace Gregory L. 
Published: July 2013

AbstractAlthough circumscribed interests are pathognomonic with autism, much about these interests remains unknown. Using the Interests Scale (IS), this study compares interests between 76 neurotypical (NT) individuals and 109 individuals with high-functioning autism spectrum disorder (HF-ASD) matched groupwise on age, IQ, and gender ratio. Participants and their parents/caregivers completed diagnostic measures (the Autism Diagnostic Interview—Revised and the Autism Diagnostic Observation Schedule; HF-ASD only), cognitive tests (Wechsler IQ Scales), and questionnaires (the Repetitive Behavior Scale—Revised, the Behavior Rating Inventory of Executive Function, and the Social Responsiveness Scale), in addition to the IS. Consistent with previous research, HF-ASD and NT individuals did not differ in number of interest areas, but the types of interests and intensity of those interests differed considerably. Using only the IS intensity score, 81% of individuals were correctly classified (NT or HF-ASD) in a logistic regression analysis. Among individuals with HF-ASD, Interests Scale scores were significantly related to Autism Diagnostic Observation Schedule, Behavior Rating Inventory of Executive Function, Repetitive Behavior Scale—Revised, and Social Responsiveness Scale scores, but they were not related to Autism Diagnostic Interview—Revised scores, IQ, gender, age, or psychotropic medication use. The type and intensity, but not the number, of interests distinguish high-functioning individuals with ASD from NT individuals.
Prospective developmental subtypes of alcohol dependence from age 18 to 32 years: Implications for nosology, etiology, and intervention
Authors: Meier Madeline H. , Caspi Avshalom , Houts Renate , Slutske Wendy S. , Harrington Honalee , Jackson Kristina M. , Belsky Daniel W. , Poulton Richie , Moffitt Terrie E. 
Published: July 2013

AbstractThe purpose of the present study is to identify child and adult correlates that differentiate (a) individuals with persistent alcohol dependence from individuals with developmentally limited alcohol dependence and (b) individuals with adult-onset alcohol dependence from individuals who never diagnose. There are 1,037 members of the Dunedin Longitudinal Study, which is a birth cohort followed prospectively from birth until age 32. Past-year DSM-IV alcohol dependence diagnoses are ascertained with structured diagnostic interviews at ages 18, 21, 26, and 32. Individuals are classified as developmentally limited, persistent, or adult-onset subtypes based on their time-ordered pattern of diagnoses. The persistent subtype generally exhibits the worst scores on all correlates, including family psychiatric history, adolescent and adult externalizing and internalizing problems, adolescent and adult substance use, adult quality of life, and coping strategies. The prospective predictors that distinguished them from the developmentally limited subtype involved family liability, adolescent negative affectivity, daily alcohol use, and frequent marijuana use. Furthermore, young people who develop the persistent subtype of alcohol dependence are distinguished from the developmentally limited subtype by an inability to reduce drinking and by continued use despite problems by age 18. The adult-onset group members are virtually indistinguishable from ordinary cohort members as children or adolescents; however, in adulthood, adult-onset cases are distinguished by problems with depression, substance use, stress, and strategies for coping with stress. Information about age of onset and developmental course is fundamental for identifying subtypes of alcohol dependence. Subtype-specific etiologies point to targeted prevention and intervention efforts based on the characteristics of each subtype.
AVICENNA'S CONCUPISCENCE
Authors: Lameer Joep 
Published: July 2013

AbstractPhilosophical and medical excellence notwithstanding, Avicenna was far from being an otherwordly person who buried himself in his books. He had an extraordinarily adventurous life and is reported to have been fond of good food, drink, and lovemaking. This article discusses the wellknown but quite unusual view that he died of having too much sex. A detailed analysis of the sources and a common-sense approach to some of their medical claims will show that this allegation is not supported by any evidence whatsoever. Quite the opposite: it will be argued that the main source on which all later reports must taken to depend has been tampered with in two places to produce the image that we know. Thus, we must assume that people hostile to Avicenna and his philosophy are behind this, their forgery most likely having been committed in the first half of the twelfth century AD.
Cheatham platinum stent implantation in children with coarctation of the aorta: single-centre short-term, intermediate-term, and long-term results from Turkey
Authors: Baykan Ali , Narin Nazmi , Ozyurt Abdullah , Argun Mustafa , Pamukcu Ozge , Mavili Ertugrul , Sezer Saadettin , Onan Sertac H. , Uzum Kazım 
Published: July 2013

AbstractObjectives:Our aim was to evaluate patients who were treated by percutaneous stent implantation.Methods:Patients with aortic coarctation (n = 35) who had been treated with 38 stents – 12 bare and 26 covered – were evaluated. The demographics and procedural and follow-up data were recorded from hospital registers and compared according to patient specifications, for example, weight and coarctation nature.Results:The procedure was successful in all patients. There was a statistically significant difference between the patients with native coarctation (n = 17) and those with recurrent coarctation (n = 18) in terms of pre-procedural blood pressures, systolic gradients, coarctation diameters, and the ratio of the coarctation site diameter to the descending aorta diameter. Although all patients received antihypertensive drugs before the procedure, the drug was discontinued in 26 patients during follow-up (p < 0.001). Stent migration was observed in four patients with recurrent coarctation (11.4%), and peripheral arterial injury was seen in three patients (8.5%). The mean follow-up time was 34 ± 16 months. On average, 21 (6–42) months after the procedure, six patients underwent cardiac catheterisation. At least 2 years after the procedure, tomography was performed in 20 patients (57.2%). Patients who were evaluated by multi-slice computerised tomography revealed no pathologies. There was no statistically significant difference between the five patients weighing less than 20 kg and the other 30 patients in terms of demographic and procedural characteristics, procedure success and complication rates, and follow-up data.Conclusion:Stent implantation for aortic coarctation is a method yielding satisfactory results in reducing coarctation gradients, efficient enlargement of the lesion area, and resolution of hypertension for children, including those weighing less than 20 kg.
The clinical application of ABCB1 genotyping in antidepressant treatment: a pilot study
Authors: Breitenstein Barbara , Scheuer Sandra , Pfister Hildegard , Uhr Manfred , Lucae Susanne , Holsboer Florian , Ising Marcus , Brückl Tanja M. 
Published: July 2013

BackgroundThe gene product of the ABCB1 gene, the P-glycoprotein, functions as a custodian molecule in the blood–brain barrier and regulates the access of most antidepressants into the brain. Previous studies showed that ABCB1 polymorphisms predicted the response to antidepressants that are substrates of the P-gp, while the response to nonsubstrates was not influenced by ABCB1 polymorphisms. The aim of the present study was to evaluate the clinical application of ABCB1 genotyping in antidepressant pharmacotherapy.MethodsData came from 58 depressed inpatients participating in the Munich Antidepressant Response Signature (MARS) project, whose ABCB1 gene test results were implemented into the clinical decision making process. Hamilton Depression Rating Scale (HAM-D) scores, remission rates, and duration of hospital stay were documented with dose and kind of antidepressant treatment.ResultsPatients who received ABCB1 genotyping had higher remission rates [χ2(1) = 6.596,p= 0.005, 1-sided] and lower Hamilton sores [t(111) = 2.091,p= 0.0195, 1-sided] at the time of discharge from hospital as compared to patients without ABCB1 testing. Among major allele homozygotes for ABCB1 single nucleotide polymorphisms (SNPs) rs2032583 and rs2235015 (TT/GG genotype), an increase in dose was associated with a shorter duration of hospital stay [rho(28) = –0.441,p= 0.009, 1-sided], whereas other treatment strategies (eg, switching to a nonsubstrate) showed no significant associations with better treatment outcome.DiscussionThe implementation of ABCB1 genotyping as a diagnostic tool influenced clinical decisions and led to an improvement of treatment outcome. Patients carrying the TT/GG genotype seemed to benefit from an increase in P-gp substrate dose.ConclusionResults suggest that antidepressant treatment of depression can be optimized by the clinical application of ABCB1 genotyping.
Backward and trigger-based language models for statistical machine translation
Authors: XIONG DEYI , ZHANG MIN 
Published: July 2013

AbstractThe language model is one of the most important knowledge sources for statistical machine translation. In this article, we present two extensions to standard n-gram language models in statistical machine translation: a backward language model that augments the conventional forward language model, and a mutual information trigger model which captures long-distance dependencies that go beyond the scope of standard n-gram language models. We introduce algorithms to integrate the two proposed models into two kinds of state-of-the-art phrase-based decoders. Our experimental results on Chinese/Spanish/Vietnamese-to-English show that both models are able to significantly improve translation quality in terms of BLEU and METEOR over a competitive baseline.
Characterization of Sudanese pearl millet germplasm for agro-morphological traits and grain nutritional values
Authors: Bashir Elfadil M. A. , Ali Abdelbagi M. , Ali Adam M. , Melchinger Albrecht E. , Parzies Heiko K. , Haussmann Bettina I. G. 
Published: July 2013

Pearl millet (Pennisetum glaucum(L.) R. Br.) is an important staple cereal cultivated in the arid and semi-arid tropics of Asia and Africa, regions severely affected by malnutrition. Knowledge about the extent of genetic variability and patterns of agro-morphological variation in local germplasm from a target region is an important prerequisite for efficient crop improvement. To assess the potential of Sudanese pearl millet landraces as sources of desirable traits for pearl millet improvement including biofortification, a total of 225 accessions were evaluated in Sudan at three locations for agro-morphological traits and at one location for grain mineral nutrient contents (Fe, Zn, Ca, P, K, Mg, Mn, S, Na, Cu and β-carotene). Genetic variation was highly significant, but relatively limited for some agro-morphological traits (62–78 d to flowering, 119–188 cm plant height and 16–34 cm panicle length), pointing to the potential usefulness of a targeted diversification for these traits. Self-pollinated grain micronutrient contents showed a wide variation: 19.7–86.4 mg/kg for Fe and 13.5–82.4 mg/kg for Zn. Significant and positive correlations among most of the nutritional traits were observed; therefore, enhancement of the concentrations of some nutrients will lead to the improvement of other related nutrients. No significant associations were observed between the nutritional and agro-morphological traits, indicating good prospects for simultaneous improvement of both trait categories. No clear patterns of geographic differentiation for specific traits were detected for the Sudanese pearl millet. Nutrient-rich accessions were identified and those with acceptable agro-morphological traits are encouraging materials for future pearl millet biofortification programmes in Sudan.
Influences of Fundamental Frequency, Formant Frequencies, Aperiodicity, and Spectrum Level on the Perception of Voice Gender
Authors: Skuk Verena G. , Schweinberger Stefan R. 
Published: July 2013

PurposeTo determine the relative importance of acoustic parameters (fundamental frequency [F0], formant frequencies [FFs], aperiodicity, and spectrum level [SL]) on voice gender perception, the authors used a novel parameter-morphing approach that, unlike spectral envelope shifting, allows the application of nonuniform scale factors to transform formants and more direct comparison of parameter impact.MethodIn each of 2 experiments, 16 listeners with normal hearing (8 female, 8 male) classified voice gender for morphs between female and male speakers, using syllable tokens from 2 male–female speaker pairs. Morphs varied single acoustic parameters (Experiment 1) or selected combinations (Experiment 2), keeping residual parameters androgynous, as determined in a baseline experiment.ResultsThe strongest cue related to gender perception was F0, followed by FF and SL. Aperiodicity did not systematically influence gender perception. Morphing F0 and FF in conjunction produced convincing changes in perceived gender—changes that were equivalent to those for Full morphs interpolating all parameters. Despite the importance of F0, morphing FF and SL in combination produced effective changes in voice gender perception.ConclusionsThe most important single parameters for gender perception are, in order, F0, FF, and SL. At the same time, F0 and vocal tract resonances have a comparable impact on voice gender perception.Supplemental Materialhttps://doi.org/10.23641/asha.6170438
Real‐time length measurement of epidural Tuohy needle during insertion
Authors: Vaughan Neil , Dubey Venketesh N. , Wee Michael Y.K. , Isaacs Richard 
Published: July 2013

This study presents a novel technique for the measurement of insertion depth of an epidural Tuohy needle in real‐time. A wireless camera is used which transmits video images during insertion to a host computer. The computer contains the image processing algorithm to detect the visible needle in the image and measures the length. The measurement is done by HSV background removal, colour comparison and using RGB intensity profile to locate 10 mm markings on the Tuohy needle shaft. The visible length is then subtracted from the known length of the needle to calculate the depth of the needle tip. The camera can be placed in the operating theatre between 50 and 100 cm away from the needle insertion site. Wireless camera is beneficial since it minimises disturbance to the anaesthetist and the patient and avoids ethical and sterility concerns which would be caused by bringing additional equipment into the hospital room. The speed of the image processing technique is 10 frames per second with a maximum error of ±3 mm. The image processing failure rate was 3 frames out of 150 which gave an overall reliability of 97.8% during insertion. Also this enables continuous needle depth monitoring during insertion by storing measurements into a data file. The purpose of measuring needle depth in real time is to precisely place the needle in the epidural space.
SOX2–LIN28/let-7 pathway regulates proliferation and neurogenesis in neural precursors
Authors: Cimadamore Flavio , Amador-Arjona Alejandro , Chen Connie , Huang Chun-Teng , Terskikh Alexey V. 
Published: July 2013

Significance
The transcription factor SOX2 plays a critical role in self-renewal and neuronal differentiation of neural precursors (NPCs); however, the molecular mechanisms underlying its functions are poorly understood. We found that SOX2 regulates the expression of LIN28, a suppressor of let-7 microRNA biogenesis. Exogenous LIN28 rescued the NPC proliferation and some neurogenic deficits in the absence of SOX2. We identified let-7i as a novel and potent inhibitor of neuronal differentiation that represses proneural genes. The discovery of SOX2–LIN28/let-7 pathway that maintains both NPC proliferation and neurogenic potential will enhance our understanding and therapeutic development relevant to neurodegeneration and brain tumors.