bluuebunny/crossref_metadata_2025_split huggingface dataset:
Copy number increase of ACTN4 is a prognostic indicator in salivary gland carcinoma
Authors: Watabe Yukio , Mori Taisuke , Yoshimoto Seiichi , Nomura Takeshi , Shibahara Takahiko , Yamada Tesshi , Honda Kazufumi 
Published: February 2014

AbstractCopy number increase (CNI) of ACTN4 has been associated with poor prognosis and metastatic phenotypes in various human carcinomas. To identify a novel prognostic factor for salivary gland carcinoma, we investigated the copy number of ACTN4. We evaluated DNA copy number of ACTN4 in 58 patients with salivary gland carcinoma by using fluorescent in situ hybridization (FISH). CNI of ACTN4 was recognized in 14 of 58 patients (24.1%) with salivary gland carcinoma. The cases with CNI of ACTN4 were closely associated with histological grade (P = 0.047) and vascular invasion (P = 0.033). The patients with CNI of ACTN4 had a significantly worse prognosis than the patients with normal copy number of ACTN4 (P = 0.0005 log‐rank test). Univariate analysis by the Cox proportional hazards model showed that histological grade, vascular invasion, and CNI of ACTN4 were independent risk factors for cancer death. Vascular invasion (hazard ratio [HR]: 7.46; 95% confidence interval [CI]: 1.98–28.06) and CNI of ACTN4 (HR: 3.23; 95% CI: 1.08–9.68) remained as risk factors for cancer death in multivariate analysis. Thus, CNI of ACTN4 is a novel indicator for an unfavorable outcome in patients with salivary gland carcinoma.
On the Configurational Stability of Chiral, Nonracemic Fluoro‐ and Iodo‐[D1]Methyllithiums
Authors: Kail Dagmar C. , Malova Krizkova Petra , Wieczorek Anna , Hammerschmidt Friedrich 
Published: February 2014

AbstractEnantiomerically pure fluoro‐[D1]methyllithium and iodo‐[D1]methyllithiums of up to 92 % ee were generated by transmetalation of the corresponding stannanes with MeLi in THF at various temperatures. The intermediate halo‐[D1]methyllithiums were trapped with benzaldehyde or acetophenone already present in excess in the reaction mixture to either give halohydrins or to disintegrate to carbene. The fluoro‐[D1]methyllithiums were found to be microscopically configurationally stable within the tested range of −95 to 0 °C, but chemically only stable at temperatures below −95 °C due to a rapidly increasing portion disintegrating to carbene. The iodo‐[D1]methyllithiums were configurationally labile relative to the rate of addition to PhCHO at all temperatures tested (−95 to −30 °C). Disintegration to carbene interfered as well.
ChemInform Abstract: Solid Phase Metallurgy Strategy to Sub‐5 nm Au—Pd and Ni—Pd Bimetallic Nanoparticles with Controlled Redox Properties.
Authors: Tang Yu , Xu Shaodan , Dai Yihu , Yan Xiaoqing , Li Renhong , Xiao Liping , Fan Jie 
Published: February 2014

AbstractThe title bimetallic nanoparticles are prepared by loading Au and Pd, or Ni and Pd nanoparticles into mesoporous silica with extra large pores followed by thermal annealing at 550 °C under H2/Ar atmosphere.
ChemInform Abstract: Synthesis, Structure and Photoluminescence Properties of Amine‐Templated Open‐Framework Bismuth Sulfates.
Authors: Marri Subba R. , Behera J. N. 
Published: February 2014

AbstractTwo organically‐templated Bi sulfates [H2DABCO][Bi(SO4)2(NO3)] (I) (DABCO: 1,4‐diazabicyclo[2.2.2]octane) and [H2pip]4 [Bi4(SO4)10(H2O)4] (II) (pip: piperazine) with open architecture are prepared from a mixture of Bi(NO3)3, H2O, H2SO4, and DABCO or piperazine (air, 25 °C, 1 month, yields of 80 and 73%, resp.).
ChemInform Abstract: In Search of the True Structure of the Sodium Chromium Alum II: Crystal Growth and Structure of the Double Salt NaCr(SO4)2(H2O)6· (CH3OH)0.6(2)·(H2O)1.5 (5).
Authors: Rees‐Isele Luitgard , Winkler Hans‐Peter , Keller Egbert 
Published: February 2014

AbstractCrystals of the title compound are obtained from water/methanol solutions of Cr2(SO4)3(H2O)x and Na2SO4 (280 K, 8—10 d).
ChemInform Abstract: Tunable Synthesis of 3‐Acyl‐2‐naphthols and 3‐Substituted Isocoumarins via Jones Reagent Promoted Cascade Reactions of 2‐(4‐Hydroxy‐but‐1‐ynyl)benzaldehydes.
Authors: He Yan , Zhang Xinying , Shen Nana , Fan Xuesen 
Published: February 2014

AbstractIt is found that treatment of benzaldehydes of type (I) and (V) with 0.7 equivalents of Jones oxidant followed by column chromatography on silica gel pre‐eluted with NEt3 results in efficient formation of 3‐acyl‐2‐naphthols.
ChemInform Abstract: Hetereogeneous Transition‐Metal‐Free Alcohol Oxidation by Graphene Oxide Supported Iodoxybenzoic Acid in Water.
Authors: Kim Yo‐Han , Jang Hyung‐Seok , Kim Young‐O , Ahn So‐Dam , Yeo Sewon , Lee Sang‐Myung , Lee Yoon‐Sik 
Published: February 2014

AbstractA highly loaded graphene oxide supported iodoxybenzoic acid derivative is described and successfully applied as heterogeneous and recyclable reagent for the oxidation of alcohols to the corresponding aldehydes or ketones.
ChemInform Abstract: Micro and Nanobubble Based Strategy for Gas—Liquid—Solid Multiphase Reactions: Palladium‐Catalyzed Hydrogenation of Carbon—Carbon Unsaturated Bonds.
Authors: Mase Nobuyuki , Isomura Shogo , Toda Mitsuo , Watanabe Naoharu 
Published: February 2014

AbstractThe use of hydrogen micro‐ and nanobubbles results in significant improvement of the efficiency of atmospheric pressure multiphase hydrogenations of unsaturated Carbon‐carbon bonds.
ChemInform Abstract: Regioselective Palladium(II)‐Catalyzed Desulfitative Heck‐Type Reaction: Access to α‐Benzyl‐β‐keto Esters from Baylis—Hillman Adducts and Sodium Sulfinates.
Authors: Raju Kammari Bal , Mari Vellakkaran , Nagaiah Kommu 
Published: February 2014

AbstractThis new and efficient method for desulfitative Heck‐type arylation proceeds under mild conditions and tolerates a wider range of functionalities than previously reported methodologies.
ChemInform Abstract: Highly Efficient Conjugate Addition of Diethylzinc to Enones Catalyzed by Chiral Ligands Derived from (S)‐Mandelic Acid.
Authors: Rachwalski Michal , Jarzynski Szymon , Lesniak Stanislaw 
Published: February 2014

AbstractChiral bidentate ligands derived from (S)‐mandelic acid and chiral mono‐alkylated aziridines are investigated as ligands for the asymmetric Ni‐catalyzed conjugate addition of diethylzinc to enones.
ChemInform Abstract: Synthesis of Dienyl Ketones via Palladium(II)‐Catalyzed Direct Cross‐Coupling Reactions Between Simple Alkenes and Vinyl Ketones: Application to the Synthesis of Vitamin A1 and Bornelone.
Authors: Zhang Xiang , Wang Min , Zhang Ming‐Xin , Xu Yun‐He , Loh Teck‐Peng 
Published: February 2014

AbstractThe title reaction affords dienyl ketones with different E/Z‐selectivities and in case of bornelone (VIII) complete E‐selectivity is obtained.
ChemInform Abstract: Copper‐Mediated Amidation of Alkenylzirconocenes with Acyl Azides: Formation of Enamides.
Authors: Liu Hailan , Zhou Yiqing , Yan Xiaoyu , Chen Chao , Liu Qingbin , Xi Chanjuan 
Published: February 2014

AbstractThe alkenylzirconocenes are generated in situ from the corresponding alkynes and zirconocene.
ChemInform Abstract: Palladacycle‐Catalyzed Deacetonative Sonogashira Coupling of Aryl Propargyl Alcohols with Aryl Chlorides.
Authors: Hu Hao , Yang Fan , Wu Yangjie 
Published: February 2014

AbstractFor the first time the title reaction proceeds for electron‐poor, ‐neutral, and even sterically hindered electron‐rich aryl chlorides.
ChemInform Abstract: 1,6‐Carbene Transfer: Gold‐Catalyzed Oxidative Diyne Cyclizations.
Authors: Noesel Pascal , Nunes dos Santos Comprido Laura , Lauterbach Tobias , Rudolph Matthias , Rominger Frank , Hashmi A. Stephen K. 
Published: February 2014

AbstractIn the presence of a gold catalyst an unprecedented oxidative cyclization of diynes takes place.
ChemInform Abstract: Manganese(III)‐Mediated Oxidative Radical Addition of Malonates to 2‐Cyanoindoles.
Authors: Lopchuk Justin M. , Montgomery William L. , Jasinski Jerry P. , Gorjifard Sayeh , Gribble Gordon W. 
Published: February 2014

Abstract2‐Cyanoindoles (I) and (IV) undergo Mn(III)‐mediated radical addition reactions with mono‐substituted malonate‐type compounds to give indoles (III) and (VI) having a quarternary carbon substituent at C‐3.
ChemInform Abstract: RCM Approach to Complex Polycyclic α‐Hydroxy γ‐Lactams: Synthesis of Indolizinones and Pyrroloazepinones.
Authors: Gomez‐SanJuan Asier , Sotomayor Nuria , Lete Esther 
Published: February 2014

AbstractThe synthesis of the title compounds is achieved via alkylmagnesium chloride addition/RCM sequence.
ChemInform Abstract: Copper(I)‐Catalyzed Highly Regio‐ and Stereoselective Boron Addition—Protonolysis of Alkynamides to Give Alkenamides.
Authors: He Guangke , Zhang Qijun , Huang Hai , Chen Shan , Wang Qiang , Zhang Dongming , Zhang Rong , Zhu Hongjun 
Published: February 2014

AbstractThe presence of the aryl group on the alkynes is required for the formation of the products.
ChemInform Abstract: β‐Cyclodextrin‐Mediated Highly Efficient [2 + 3] Cycloaddition Reactions for the Synthesis of 5‐Substituted 1H‐Tetrazoles.
Authors: Patil Dipak R. , Wagh Yogesh B. , Ingole Pravin G. , Singh Kripal , Dalal Dipak S. 
Published: February 2014

AbstractThe use of β‐cyclodextrin as a catalyst allows efficient [2 + 3] cycloaddition reactions between nitriles and azides carrying a variety of substituents.
ChemInform Abstract: Cycloaddition versus Alkylation Reactions of 2‐Vinylindoles with α,β‐Unsaturated Carbonyl Compounds under Gold Catalysis.
Authors: Pirovano Valentina , Dell'Acqua Monica , Facoetti Diego , Nava Donatella , Rizzato Silvia , Abbiati Giorgio , Rossi Elisabetta 
Published: February 2014

AbstractThe gold‐catalyzed reaction of N‐ethoxycarbonyl substituted 2‐vinylindoles with α,β‐unsubstituted carbonyl compounds is demonstrated to produce diastereomeric mixtures of Diels—Alder products.
ChemInform Abstract: Sodium‐Hydroxide‐Mediated Synthesis of Highly Functionalized [1,6]‐Naphthyridines in a One‐Pot Pseudo Five‐Component Reaction.
Authors: Sarkar Satavisha , Das Deb K. , Khan Abu T. 
Published: February 2014

AbstractThe title reaction proceeds under mild conditions with high chemoselectivity and uses easily available materials.
ChemInform Abstract: Iodine‐Mediated Electrophilic Tandem Cyclization of 2‐Alkynylbenzaldehydes with Anthranilic Acid Leading to 1,2‐Dihydroisoquinoline‐Fused Benzoxazinones.
Authors: Dighe Shashikant U. , Batra Sanjay 
Published: February 2014

AbstractThe efficient iodine‐mediated electrophilic tandem cyclization of 2‐alkynylbenzaldehydes with anthranilic acids or 2‐aminobenzamides is reported for the first time.
ChemInform Abstract: Cobalt‐Catalyzed Asymmetric Addition of Silylacetylenes to 1,1‐Disubstituted Allenes.
Authors: Sawano Takahiro , Ou Keiyu , Nishimura Takahiro , Hayashi Tamio 
Published: February 2014

AbstractThe asymmetric addition of silylacetylenes to 1,1‐disubstituted allenes proceeds in the presence of a cobalt/chiral bisphosphine ligand to give the corresponding enynes with high enantioselectivity.
ChemInform Abstract: Chemical Investigation of an Antimalarial Chinese Medicinal Herb Picrorhiza scrophulariiflora.
Authors: Wang Hongmin , Zhao Weimin , Choomuenwai Vanida , Andrews Katherine T. , Quinn Ronald J. , Feng Yunjiang 
Published: February 2014

Abstractisolation, structure determination and antimalarial activity of three new compounds, scrophuloside C (Ia), D (Ib), hebitol III (II) along with seven known compounds
ChemInform Abstract: Nitrosporeusines A and B, Unprecedented Thioester‐Bearing Alkaloids from the Arctic Streptomyces nitrosporeus.
Authors: Yang Aigang , Si Longlong , Shi Zhenping , Tian Li , Liu Dong , Zhou Demin , Proksch Peter , Lin Wenhan 
Published: February 2014

AbstractBoth compounds exhibit inhibitory activities against the H1N1 virus in MDCK cells.
ChemInform Abstract: A Diastereodivergent Strategy for the Asymmetric Syntheses of (—)‐Martinellic Acid and (—)‐4‐epi‐Martinellic Acid.
Authors: Davies Stephen G. , Fletcher Ai M. , Lee James A. , Lorkin Thomas J. A. , Roberts Paul M. , Thomson James E. 
Published: February 2014

AbstractAsymmetric syntheses of (—)‐martinellic acid (I) and (—)‐4‐epi‐martinellic acid (II) are achieved in a multistep procedure from commercially available starting materials using a diastereodivergent strategy.
ChemInform Abstract: Enantiospecific Total Synthesis of (+)‐Tanikolide via a Key [2,3]‐Meisenheimer Rearrangement with an Allylic Amine N‐Oxide‐Directed Epoxidation and a One‐Pot Trichloroisocyanuric Acid N‐Debenzylation and N‐Chlorination.
Authors: Xie Yangla , Sun Moran , Zhou Hang , Cao Qiwei , Gao Kaige , Niu Changling , Yang Hua 
Published: February 2014

AbstractTanikolide (I) is synthesized over nine linear steps in 53% overall yield.
Outcomes of patients with metastatic melanoma treated with immunotherapy prior to or after BRAF inhibitors
Authors: Ackerman Allison , Klein Oliver , McDermott David F. , Wang Wei , Ibrahim Nageatte , Lawrence Donald P. , Gunturi Anasuya , Flaherty Keith T. , Hodi F. Stephen , Kefford Richard , Menzies Alexander M. , Atkins Michael B. , Long Georgina V. , Sullivan Ryan J. 
Published: February 2014

BACKGROUNDThe immunotherapy (IT) agents ipilimumab and interleukin‐2 as well as BRAF inhibitors (BRAFi) vemurafenib and dabrafenib, with or without trametinib (MEK inhibitors), are all FDA‐approved treatments for BRAF metastatic melanoma, but there are few studies to guide optimal sequencing. This retrospective analysis describes the outcomes of patients treated with either BRAFi before IT or IT before BRAFi.METHODSA cohort of patients treated with BRAFi alone or with MEK inhibitor was retrospectively identified. Response rate (RR), overall survival (OS), and progression‐free survival (PFS) were evaluated for the entire cohort, subdivided by BRAFi prior to or after IT.RESULTSRR and median PFS and OS calculated from commencement of BRAFi following IT (N = 32) were 57%, 6.7 months (95% confidence interval [CI] = 4.3‐9.1 months), and 19.6 months (95% CI = 10.0‐undefined months), respectively; whereas for BRAFi initially (N = 242) were 66%, 5.6 months (95% CI = 4.7‐6.8 months), and 13.4 months (95% CI = 10.1‐17.0 months). Results were similar when controlled for prognostic variables. A total of 193 patients discontinued BRAFi, with OS of 2.9 months (range of 1.8‐4.4 months) from day of BRAFi discontinuation. Forty patients subsequently received IT with ipilimumab. Only half could complete 4 doses of ipilimumab; PFS with ipilimumab was 2.7 months (95% CI = 1.8‐3.1 months) and OS was 5.0 months (95% CI = 3.0‐8.8 months).CONCLUSIONSIn this retrospective analysis, prior treatment with IT does not appear to negatively influence response to BRAFi. Outcomes for IT with ipilimumab following BRAFi discontinuation are poor. Randomized controlled trials are needed to define if sequencing IT prior to BRAFi therapy is superior to sequencing BRAFi prior to IT. Cancer 2014;120:1695–1701. © 2014 American Cancer Society.
Complete response to induction therapy in patients with Myc‐positive and double‐hit non‐Hodgkin lymphoma is associated with prolonged progression‐free survival
Authors: Cohen Jonathon B. , Geyer Susan M. , Lozanski Gerard , Zhao Weiqiang , Heerema Nyla A. , Hall Nathan C. , Nagar Veena A. , Hemminger Jessica A. , Jones Jeffrey A. , Porcu Pierluigi , Christian Beth A. , Baiocchi Robert A. , Maddocks Kami J. , Flynn Joseph M. , Devine Steven M. , Blum Kristie A. 
Published: February 2014

BACKGROUNDMyc‐positive B‐cell non‐Hodgkin lymphoma (NHL) with or without a B‐cell chronic lymphocytic leukemia/lymphoma 2 (BCL2) rearrangement is associated with inferior progression‐free survival (PFS) and overall survival (OS). In this study, the authors reviewed the outcomes of patients with myc‐positive and double‐hit NHL at The Ohio State University.METHODSAll patients who had non‐Burkitt, aggressive B‐cell NHL from 2008 to 2011 were assessed for the t(14;18) translocation and for v‐myc avian myelocytomatosis viral oncogene homolog (CMYC) rearrangements at diagnosis, and all myc‐positive patients were included in the current analysis. Associations with clinical characteristics were described, and univariable and multivariable models were used to assess correlations between clinical variables and outcomes.RESULTSOf 49 myc‐positive patients, 29 patients also had BCL2 rearrangements (double‐hit NHL). No patients underwent autologous stem cell transplantation in first remission. For all myc‐positive patients, the median PFS was 16.6 months, and the median OS was 37.7 months. For patients who had double‐hit NHL, the median PFS was 8 months, and the median OS was 12.5 months; whereas the median PFS and OS were not reached for myc‐positive patients. A complete response (CR) after front‐line therapy, the presence of t(14;18), International Prognostic Index (IPI) group, and age were associated with PFS; whereas only the achievement of a CR and age >60 years were associated with OS in the multivariable setting. The median PFS was 3.3 months, and the median and OS was 7.0 months for patients who did not attain a CR; and the medians were not reached for patients who achieved a CR (P < .00001).CONCLUSIONSThe achievement of a CR with front‐line therapy is associated with a prolonged PFS and OS in patients with myc‐positive NHL, even after adjusting for type of initial therapy, histology, age, IPI, or the presence of a concurrent BCL2 translocation. Cancer 2014;120:1677–1685. © 2014 American Cancer Society.
Life science data analysis workflow development using the bioextract server leveraging the iPlant collaborative cyberinfrastructure
Authors: Lushbough Carol M. , Gnimpieba Etienne Z. , Dooley Rion 
Published: February 2014

SummaryIn order to handle the vast quantities of biological data gener6ated by high‐throughput experimental technologies, the BioExtract Server (bioextract.org) has leveraged iPlant Collaborative (www.iplantcollaborative.org) functionality to help address big data storage and analysis issues in the bioinformatics field. The BioExtract Server is a Web‐based, workflow‐enabling system that offers researchers a flexible environment for analyzing genomic data. It provides researchers with the ability to save a series of BioExtract Server tasks (e.g., query a data source, save a data extract, and execute an analytic tool) as a workflow and the opportunity for researchers to share their data extracts, analytic tools, and workflows with collaborators. The iPlant Collaborative is a community of researchers, educators, and students working to enrich science through the development of cyberinfrastructure—the physical computing resources, collaborative environment, virtual machine resources, and interoperable analysis software and data services—that are essential components of modern biology. The iPlant AGAVE Advanced Programming Interface, developed through the iPlant Collaborative, is a hosted, Software‐as‐a‐Service resource providing access to a collection of high performance computing and cloud resources. Leveraging AGAVE, the BioExtract Server gives researchers easy access to multiple high performance computers and delivers computation and storage as dynamically allocated resources via the Internet. © 2014 The Authors. Concurrency and Computation: Practice and Experience published by John Wiley & Sons Ltd.
Graphene Oxide/α‐Bi2O3 Composites for Visible‐Light Photocatalysis, Chemical Catalysis, and Solar Energy Conversion
Authors: Som Tirtha , Troppenz Gerald V. , Wendt Robert , Wollgarten Markus , Rappich Jörg , Emmerling Franziska , Rademann Klaus 
Published: February 2014

AbstractThe growing challenges of environmental purification by solar photocatalysis, precious‐metal‐free catalysis, and photocurrent generation in photovoltaic cells receive the utmost global attention. Here we demonstrate a one‐pot, green chemical synthesis of a new stable heterostructured, ecofriendly, multifunctional microcomposite that consists of α‐Bi2O3 microneedles intercalated with anchored graphene oxide (GO) microsheets (1.0 wt %) for the above‐mentioned applications on a large economical scale. The bare α‐Bi2O3 microneedles display two times better photocatalytic activities than commercial TiO2 (Degussa‐P25), whereas the GO‐hybridized composite exhibits approximately four to six times enhanced photocatalytic activities than the neat TiO2 photocatalyst in the degradation of colored aromatic organic dyes (crystal violet and rhodamine 6G) under visible‐light irradiation (300 W tungsten lamp). The highly efficient activity is associated with the strong surface adsorption ability of GO for aromatic dye molecules, the high carrier acceptability, and the efficient electron–hole pair separation in Bi2O3 by individual adjoining GO sheets. The introduction of Ag nanoparticles (2.0 wt %) further enhances the photocatalytic performance of the composite over eightfold because of a plasmon‐induced electron‐transfer process from Ag nanoparticles through the GO sheets into the conduction band of Bi2O3. The new composites are also catalytically active and catalyze the reduction of 4‐nitrophenol to 4‐aminophenol in the presence of borohydride ions. Photoanodes assembled from GO/α‐Bi2O3 and Ag/GO/α‐Bi2O3 composites display an improved photocurrent response (power conversion efficiency ∼20 % higher) over those prepared without GO in dye‐sensitized solar cells.
Oxidorhenium(V) Complexes with Benzoylselenoureas
Authors: Schwade Vania D. , Hagenbach Adelheid , Schulz Lang Ernesto , Klauke Karsten , Mohr Fabian , Abram Ulrich 
Published: February 2014

AbstractOxidorhenium(V) complexes with N,N‐dialkyl‐N′‐benzoylselenoureas (HL) were prepared from reactions with (NBu4)[ReOCl4]. The formation of compounds such as [ReO(L‐κO,Se)2(OMe)] or [{ReO(L‐κO,Se)2}2O] suggests parallels with the established chemistry of corresponding benzoylthioureas, while the isolation of unusual species such as [ReO(L‐κO,Se)2(L‐κSe)], [{ReO(L‐κO,Se)2}2Se3] and the formation of the respective diselenide suggest a more complicated reaction pathway with the unstable selenium compounds, and one in which degradation products of the ligands also plays a role.
Aluminum Compounds Containing Pyrrole–Imine Ligand Systems – Synthesis, Characterization, Structure Elucidation, Ring‐Opening Polymerization, and Catalytic Meerwein–Ponndorf–Verley Reaction
Authors: Hsu Shu‐Ya , Hu Ching‐Han , Tu Cheng‐Yi , Lin Chia‐Her , Chen Ren‐Yung , Datta Amitabha , Huang Jui‐Hsien 
Published: February 2014

AbstractThe reactions of AlMe3 with the tridentate pyrrole ligand precursor C4H3NH(2‐CH=NCH2Py) and subsequent treatment of the derivatives with small organic molecules such as 2,6‐diisopropylphenol or dibenzoylmethane were conveniently performed, and the products were characterized. The reaction between 1 equiv. of AlMe3 and 1 equiv. of a pyrrole–imine–pyridine ligand in toluene affords [Al{C4H3N(CHNCH2Py)Me2}] (1) in high yield. In addition, the use of 2 equiv. of AlMe3 with the same tridentate precursor results in the formation of a dialuminum compound [AlMe3{C4H3N(CHNCH2‐Py)AlMe2}] (2) in moderate yield. Furthermore, the combination of 1 with either 1 or 2 equiv. of 2,6‐diisopropylphenol or 2 equiv. of dibenzoylmethane in toluene yields aluminum monophenoxide or diphenoxide compounds [Al{C4H3N(CHNCH2‐Py)Me(O‐2,6‐iPr2C6H3)}] (3) and [Al{C4H3N(CHNCH2‐Py)}(O‐2,6‐iPr2C6H3)2] (4), respectively, as well as an aluminum bis‐diketonate compound, [Al{C4H3N(CHNCH2‐Py)}(PhCOCHCOPh)2] (5). All of the aforementioned derivatives were characterized by 1H and 13C NMR spectroscopy, and their solid‐state molecular structures were determined by single‐crystal X‐ray diffraction. The geometries of 1–5 show that the pyrrole ligand exists in the pyrrolyl–imine and azafulvene–amido resonance forms. Compounds 1, 3, 4 and 5 were used in the ring‐opening polymerization of ϵ‐caprolactone in the presence of BnOH and in the catalytic Meerwein–Ponndorf–Verley (MPV) reaction of 1‐naphthalenemethanol and 2‐naphthalenecarbaldehyde.