bluuebunny/crossref_metadata_2025_split huggingface dataset:
1392 – Treated Diabetes Mellitus In Institutionalized Patients With Schizophrenia
Authors: Agarwal S.K. 
Published: July 2013

IntroductionPatients with schizophrenia have higher cardiovascular morbidity and mortality compared to the general population. They also have a high levels of cardiovascular mortality risk factors: hypertension, smoking, hyperglycemia, physical inactivity, obesity and dyslipidemia, However, the presence of type 2 diabetes mellitus in institutionalized patients with schizophrenia has not been well studied.ObjectivesTo establish an association between type 2 diabetes mellitus and schizophrenia in patients living in residential homes.AimsTo confirm a high prevalence of diabetes mellitus treatment in these patients.MethodsFour residential institutions for patients with schizophrenia were chosen for the study. There were a total of 145 patients with schizophrenia. The first had 48 patients, males 30 and females 18, the second had 42 patients; 29 males 13 females, the third had 27 patients; 13 males and 14 females and the fourth had 28 patients; 15 males and 13 females. Computerized pharmacy print outs and records from the institutions and our office charts were reviewed.ResultsOf the 145 institutionalized schizophrenia patients, there were 87 males (60%) and 58 females (40%). The average age was 55.76 years. 39(27%) of 145 patients were on treatment for DM; 106(73%) had no diabetes mellitus; 18 (21%) of 87 males had DM and 69 (79%) had no DM; 23 (40%) of 58 females had DM and 35(60%) had no DM.ConclusionType II diabetes mellitus is extremely common (27%) in institutionalized patients with schizophrenia. Due to close medical monitoring, awareness and treatment is one hundred percent.
1393 – The Study On Validity And Reliability Of Questionnaires Related To Family Environment
Authors: Fu Y. , Hou X. , Meng H. , Qin Q. , Zheng Y. , Qiu T. , Li T. 
Published: July 2013

ObjectivesTo introduce some questionnaires related to family environment such as FAD-GFS (The General Functioning Scale of the MacMaster Family Activity Device), SLE (stressful life events), FSQ (Family Stresses Questionnaire), FLQ (Family Life Questionnaire), EFQ (Everyday Feelings Questionnaire) and evaluate their validity and reliability.MethodsUsing cross-sectional design. The general questionnaire, FAD-GFS, SLE, FSQ, FLQ, EFQ were used to collect information about family environment from 504 parents of only children FACESII-CV and Index of General Affect were used as scale of criteria related.ResultsThe reliability and validity of FAD-GFS, SLE, FSQ, FLQ, EFQ is: Cronbach coefficient were 0.695 to 0.749; re-test reliability were 0.712 to 0.901; The scores of the scale in those questionnaires were correlated with each factor significantly and the coefficient of correlation is more than those between each factor of those scales. The correlation between the scores of FSQ, EFQ and the scores of Index of General Affect was-0.192, 0.539; The correlation between the scores of FAD-GFS, FLQ the score of total and three factor differently and the scores of family cohesion scores (FACESII-CV) was -0.423, 0.237, 0.514, 0.302, 0.210.ConclusionFAD-GFS, SLE, FSQ, FLQ, EFQ has good reliability and validity, in line with requirements of psychometric and is useful as a tool to evaluate the family environment.
1394 – Suicidal Attempts Among The Military Servants During The Adaptation Period
Authors: Mehdiyev E.S. 
Published: July 2013

IntroductionThe hardness of military service, the implementation of behavior of a person within the charter and the type of the personality are the important factors that led to the suicidal attempts during the adaptation period.MethodsCurrent analysis were 95 militaries, who surveyed and treated at psychiatric and surgery department of Central Clinic Hospital of Armed Forces, after “unlucky” attempts of suicide (analysis for the period 2001–2011). Aged between 18–21.Results64.1% of the suicidal attempts of militaries during the adaptation period was observed in the first 6 months. 18.2% of them registered in the first month. In general, 77.7% of surveyed have secondary or incomplete secondary education. On time of days the greatest rating of suicides 37,8% fell at evening time. There were no complications in hereditary mental illnesses among the 93.9% of surveyed (complications only in 6.0% of them). Depending on the daytime and the season, 53.3% of suicidal attempts was observed at noon and 27.7% of suicidal attempts registered in autumn and winter. Only 24.8% of suicidal attempts made by military officers (85.1% by soldiers).ConclusionsMain causes of suicide among the conscripts are: severities during military service adaption owing to weak preinduction training, low mental attitude and motivation of soldier caused with the omission in education, the current situation in the family, targeting and mockery from fellow servicemen; heavy moral climate in some military units, increased physical and mental stress associated with understaffing personnel of military units, and other negative factors in military sevice activities.
1420 – Patient's Language Proficiency And Inpatient Depression Treatment
Authors: Bermejo I. , Kristion L. , Härter M. 
Published: July 2013

ObjectiveTo analyze process and outcome quality of inpatient depression treatment depending on German language proficiency.MethodDocumentation of patients in 24 psychiatric hospitals in Baden-Württemberg (South Germany). The following three groups were matched according to age, gender, and education: native German speakers, non-native speakers with good German proficiency, and non-native speakers with limited German proficiency (67 in each group).ResultsGermans received more group psychotherapy than the other two groups (p = .003). No differences were found regarding pharmacotherapy. Non-native speakers with limited German proficiency were discharged an average of 19 days earlier than German speakers and 7 days earlier than non-native speakers with good German proficiency (p = .02). Compared to Germans, twice as many non-native patients with good German proficiency and nearly four times as many patients with limited German proficiency were discharged with depressive symptoms (p = .006).ConclusionResults confirm the significance of linguistic factors for the effectiveness of treatment of depressive patients and show a direct impact of linguistic factors on length of hospitalization.
1438 – Default Mode Network In Left-sided Temporal Lobe Epilepsy Patients With And Without Comorbid Affective Disorders
Authors: Shmeleva L. , Lebedev A. , Kissin M. 
Published: July 2013

Affective disorders are common in patients with temporal lobe epilepsy, especially in cases of left-sided epileptic focus localization (lsTLE).AimTo characterize connectivity patterns of brain default mode network (DMN) in lsTLE patients with and without anxiety and depressive disorders.Subjects and methods28 lsTLE patients, divided into two groups: patients with (“affective” group) and without anxiety- depressive symptoms. Beck Depression Inventory (BDI), Hospital Anxiety Depressive Scale (HADS), Hamilton Anxiety Scale (HAM-A) and Montgomery-Asberg Depressive Rating Scale (MADRS) were used to assess affective symptoms. All subjects underwent 9-min resting-state fMRI scanning session. Independent component analysis (ICA) was used to isolate DMN. The resulted maps were compared in groups using two-sample t-test. The results were considered as statistically significant according to threshold of p < 0.005 with a 10-voxel extent that has recently been shown to produce an optimal balance between Types I and II error rates in fMRI studies (Lieberman, 2009). The data were processed and analyzed using SPM8 and “GIFT” toolbox for ICA “GIFT”.ResultsMild depression and moderate-severe anxiety levels were observed in the "affective" group. Significantly increased functional connectivity was found in “affective” group in the right cerebellum (culmen), right gyrus fusiformis, dorsolateral prefrontal and midcingulate area, and in the left insula.ConclusionsWe found that brain DMN is altered by affective disorders associated with lsTLE. The observed regional pattern of difference can reflect the impaired levels of self-control often present in lsTLE patients with affective symptoms
1440 – Anterior Hippocampal Connectivity And Response To Frustration In Major Depression
Authors: Lebedev A.V. , Abritalin E.Y. , Lebedeva A.K. , Shmeleva L.M. , Korzenev A.V. 
Published: July 2013

IntroductionMajor depressive disorder (MDD) is associated with low frustration tolerance, which is a risk factor for suicide. Hippocampal structural and functional abnormalities have been documented to play one of the crucial roles in the pathophysiology of depression. Recent studies have revealed functional differentiation of the hippocampus. Thus, activity of the anterior part was shown to be associated with negative affect mediation.ObjectivesTo investigate brain mechanisms of frustration, comparing its impact on anterior hippocampal connectivity in MDD patients and healthy controls (HCs).Methods14 MDD and 14 HC right-handed subjects were included in the study and underwent comprehensive clinical assessment. MDD was diagnosed during psychiatric interview according to ICD-10 criteria. The Hamilton Depression Rating Scale was additionally used to assess depressive symptoms. The original Stroop test was modified to evoke a state of frustration by administrering impossible task conditions and negative feedback during 10-min functional magnetic resonance scanning session. Psychophysiological interactions were used to analyze left and right anterior hippocampal functional connectivity changes in response to frustration. The resulted Z-maps were adjusted using Z > 2.3 threshold and a (corrected) cluster significance threshold of p = 0.05.ResultsIncreased functional connectivity of the left anterior hippocampus in response to frustration was significantly higher in MDD patients compared to HCs in the pars opercularis of the right prefrontal cortex and bilateral posterior cingulate regions.ConclusionThe results revealed that depressed patients demonstrate abnormally increased anterior hippocampal response to frustration, suggesting that hippocampal-neocortical network impairment may contribute to decreased frustration tolerance associated with MDD
1449 – A Novel Approach Of Watching Movies And Conducting Therapy For Psychiatric Inpatients
Authors: Yazici E. , Ulus F. , Selvitop R. , Yazici A.B. , Aydin N. 
Published: July 2013

ObjectiveUsing movies in psychiatric group therapy & rehabilitation classes provides ‘Entertainment, Education, Empowerment’ for the participants. We have provided such a setting where severely ill psychiatric inpatients. We aimed to describe the “Watching Cinema- Group Therapy” implementation for 500 inpatients in one year.MethodSelected movie clips were watched in the morning and group therapy session took place in the afternoon. The patients were instructed to watch the film closely, and if required, ask for certain scenes to be replayed for a better understanding. It was followed by review of the film.ResultsWe observed that these activities have encouraged the patients to talk about their beliefs, thoughts and feelings while discussing the characters and stories. We have also used as a reward for the patients who have therapeutic alliance. It motivated them to do something instead of being stayed in the room. Short movie scenes were more useful to follow up the films for the patients who have been administrated high doses of drugs.ConclusionsIt is the ingenuity and creative approaches of the educators and healers using movies in favor of behavioral health improvement. Movies are strong and important tools to be used for positive as well as productive means in treatment and teaching.
1458 – Features Of Psychomotor Development Of Children With Autistic Spectrum Disorder
Authors: Goryacheva T. , Nikitina J. 
Published: July 2013

Autistic Spectrum Disorder (ASD) includes a wide range of various impairments demanding a special approach on every single stage of development.The aim of the research was finding out the features of psychomotor development of children with ASD. Accordingly to the aim the research had following objectives:1)Detection of impairment mechanism of regulation of psychic process belonging to different levels, based on the analyses of2)normal intrauterine psychic development.3)Marking out several groups of children having different levels of psychomotor development.4)Working out the directions of intervention and evaluation their efficiency.ResultsThe analyses of normal intrauterine psychic development, based on principle of reconfiguration of cross-functional connections, system organization and construction of psychic functions hierarchy, allowed marking out four groups.1)Sensory level of psychic development, serving for keeping the internal homeostasis.2)Perception level of psychic development, working out a certain range of automatisms.3)Level of bodily-spatial analyses, helping to master either inner or outer space.4)Voluntary level of psychic development, building not vertical but horizontal inter-hemispheric connections.For every group of children we have marked out the diagnostic indications and stated the correction tasks. We propose the whole structure of sessions: sequence, periodicity, evaluation criteria for psychomotor correction. The correction method does not have a hard fixed structure, its application to children having Autistic Spectrum Disorder demands individual approach. It also has a range of contra-indications
1460 – Translation And Validation Study Of The Subjective Happiness Scale (shs) In Greek General Population, Diabetes Mellitus And Patients With Emotional Disorders
Authors: Lyrakos G.N. , Dragioti H. , Batistaki C. , Spinaris V. 
Published: July 2013

IntroductionThe SHS is a brief four-item measure of global subjective happiness rated on a Likert scale from 1 (strongly disagree) to 7 (strongly agree). SHS is suited for different age, occupational, linguistic, and cultural groups, is easy to implement and its short form possesses measurement accuracy.ObjectivesTo test the psychometric properties of SHS.AimsTo validate an easy to use and valid measurement, for primary care and during treatment assessment in psychiatric patients with emotional disorder(PPED) and general population (GP) in Greece.MethodsTranslation was performed using the multiple forward and backward translation protocol. Life orientation test (GrLOT-R), Depression anxiety stress scale (DASS) and Satisfaction with life Scale (SWLS), was also administered to check construct validity of SWLS.Results856 adults participated, 218 (25.5%) males, 638 (74.5%) females. The total scale of the SWLS had a coefficient alpha of .756. Item - total correlations where from .223-.735. Factor analysis has supported a unidimensional model with 1 factor explaining 59.4% of the total variance. Mean scores differed significantly between GP (M=18.4±4.4) and PPED (M=15.2±4.2) (Mean differences=4.622 p< .001). There was significant negative correlation with stress (r=-.443 p< .001) anxiety (r=-.350 p< .001) and depression (-.416 p< .001) and positive with GrLOT-R (r=.574 p< .001) and SWLS (r=.678 p< .001).ConclusionsThe results of the current validation study suggest that the Greek translation of the SHS is both reliable and valid, with good construct and discriminant validity and psychometric properties close to those reported in the international literature.
1465 – Osmotic-release Oral System Methylphenidate (oros-mph) Treatment Of Adult Prison Inmates With Adhd: a Randomised Controlled Trial With Open-label Extension
Authors: Ginsberg Y. , Hirvikoski T. , Grann M. , Lindefors N. 
Published: July 2013

IntroductionADHD is associated with pervasive cognitive, emotional and functional impairments and increased rates of coexisting disorders. Epidemiological studies indicate 25-45% of prison inmates to have ADHD. However, ADHD is often unrecognised in prison inmates and stimulant treatment was not previously evaluated in this group.ObjectivesProvide effective treatment for prison inmates established with ADHD.AimsEvaluate efficacy and long-term effectiveness of osmotic-release oral system methylphenidate (OROS-MPH) in adult male long-term prison inmates with ADHD.MethodsA 5-week randomised, double-blind, placebo-controlled, fixed-dose (72 mg/d) trial was conducted in 30 prison inmates with ADHD and coexisting disorders. In a following 47-week open-label extension (OLE), flexible-dosing OROS-MPH was provided alongside psychosocial interventions within a high-security Swedish prison. Primary outcome was change in ADHD symptoms after 5 weeks (CAARS: O-SV). Secondary outcomes included self-reported ADHD symptoms, global severity, global functioning, cognition, motor activity, institutional behaviour and quality of life.ResultsOROS-MPH was highly effective and overall safe, both in the short-term relative to placebo (Cohen’s d=2.17; NNT=1.1), and in the long-term when provided alongside psychosocial interventions. Treatment continued to improve ADHD symptoms, global functioning, motor activity, cognition, quality of life, and behaviour control over the 47-week OLE. No drug misuse was reported and a majority of participants completed rehabilitation programs.ConclusionsOROS-MPH effectively improved symptoms and functional impairments of ADHD in prison inmates with ADHD. We suggest that OROS-MPH provided alongside rehabilitation programs could be a feasible and effective multimodal intervention for adults with ADHD and coexisting disorders within a prison setting
1473 – Seasonal Pattern In Bipolar Disorder: Prevalence, Clinical Characteristics And Gender Influence
Authors: Geoffroy P.A. , Etain B. , Scott J. , Boudebesse C. , Lajnef M. , Leboyer M. , Bellivier F. 
Published: July 2013

IntroductionCircadian rhythm pathways are highlighted in a number of etiological models of bipolar disorder (BD). More than 25% of bipolar patients may present seasonal pattern (SP). However, there is very limited scientific data on the prevalence of SP, its clinical manifestations and any gender influence.MethodsCaucasian individuals who met DSM-IV criteria for BD I or II were recruited from three university-affiliated psychiatric departments in France (Paris, Bordeaux, Nancy). SP was defined according to DSM-IV criteria. Clinical and socio- demographic variables were obtained from structured interviews with the patients and their relatives.ResultsFour hundred and fifty-two bipolar patients (n=452) in euthymic state were included in the study, 102 of them (23%) were considered as having SP according to DSM-IV criteria. Multivariate analysis showed a significant association of BD patients with SP for bipolar II subtype (OR=1.99, p=0.013), rapid cycling (OR=2.04, p=0.02), eating disorder (OR=2.93, p=0.003) and the total number of depressive episodes (OR=1.12, p=0.002). 71% of cases were correctly classified by this analysis. However, when stratifying the analyses by gender, SP was associated with BD II subtype (OR=2.89, p=0.02) and total number of depressive episodes (OR=1.21, p=0.002) in males but with rapid cycling (OR=3.02, p=0.003) and eating disorders (OR=2.60, p=0.02) in females.ConclusionsThe high prevalence of SP in BD, its associated clinical characteristics and the observed differences between genders, suggest that SP represents a potentially important specifier of BD.
1476 – Factors Associated With Lifetime Antidepressant-induced Mania In Bipolar Disorder Patients
Authors: Brichant-Petitjean C. , Sportiche S. , Etain B. , Henry C. , Kahn J.-P. , Azorin J.-M. , Marion L. , Bellivier F. 
Published: July 2013

IntroductionAntidepressants may induce manic or hypomanic episodes. The identification of predictors of antidepressant- induced mania (AIM) is essential to improve the management of bipolar disorder (BD). However, the rare studies on AIM are generally characterized by small sample sizes, varying definitions of AIM and heterogeneous groups of patients, thus leading to conflicting results.ObjectivesTo compare a population of AIM(+) to AIM(-) patients in order to identify specific clinical factors associated with AIM.MethodsAll 252 participants met the DSM-IV criteria for BD. Only patients who reported AIM in the 90 days after the beginning of an antidepressant (with or without a mood stabilizer) were diagnosed as AIM (+) and those without any lifetime history of AIM despite lifetime antidepressant prescription were considered AIM (-). Sociodemographic and clinical factors were collected using the DIGS, ALS, AIS BIS and WURS.ResultsAIM(+) (N=74) and AIM(-) (N=178) patients did not differ significantly in terms of age, gender distribution, bipolar disorder duration and age of onset, ALS, BIS and WURS score. However, the rates of rapid cyclers, lifetime history of suicidal acts, alcohol use disorder and AIS score were significantly higher in the AIM(+)group. The type of polarity of onset was significantly different in both groups.ConclusionsA history of rapid cycling, of suicidal acts and of alcohol use disorder could be considered as risk factors of AIM in BD. Patients with these factors could therefore be identified as a vulnerable subgroup prone to manic switch with antidepressant.
1478 – Role Of Hyperthermia In Neurologic Sequelae Of The Neuroleptics-lithium Combination
Authors: Lakhal N. , El Kefi H. , Souissi S. , Jouini F. , Edhif S. , Oumaya A. , Gallali S. 
Published: July 2013

IntroductionThe combination of lithium and neuroleptic is frequently used in the treatment of bipolar disorder. After a febrile episode, some patients exhibited neurological sequelae including cerebellar, pyramidal and extra-pyramidal signs. Lithium may be the main factor of neurotoxicity but hyperthermic states are probably involved in determining brain damage.Case description58 year-old Tunisian women with a medical history of bipolar disorder treated by combination of lithium carbonate (700 mg/day) and levomepromazine (50 mg/day), was presented to the hospital with complaint of fever, cough, walking instability, choreic and dystonic abnormal movements. Physical examination found a temperature of 39 C°, rhino- bronchial, cerebellar, pyramidal, and extra-pyramidal syndrome. The additional diagnostic tests such as brain scan, MRI brain and lumbar puncture were normal. Desperate the corticoid treatment the cerebellar syndrome persisted.DiscussionThis case and some literature reviews illustrate the role of hyperthermic states in brain damage of the neuroleptics-lithium combination. Neuropathological findings showed selective degeneration of cerebellar purkinje cells. Research on this topic is recommended.