bluuebunny/crossref_metadata_2025_split huggingface dataset:
Peculiarities of the course and management of Ukrainians with post-traumatic stress disorder in the context of the Ukrainian-Russian war
Authors: Kiro Liudmyla , Urbanovych Alina , Zak Maksym 
Published: July 2024

Abstract

Background
The amount of Ukrainians with PTSD has been steadily increasing since December 2022. According to the National Health Service, amount of Ukrainians with posttraumatic-stress disorder (PTSD) in 2021 were 3,167 patients; 2022 — 7,051 patients; 2023 — 12.494 patients; 2024 (January-June) — 6,292, and for the forecasts of WHO, it will continue to increase rapidly.
Methods
The study involved 450 patients who sought psychological help at the University Clinic of Petro Mohyla Black Sea National University from January to June 2024. All patients were divided into 3 groups: 1st group — patients with PTSD (18–44 years); 2nd group — patients with PTSD (45–59 years), 3rd group — patients with PTSD (60–74 years). The examination of patients included clinical, psychological, questionnaire survey for CAPS-5 scale, SDS — 2000, and static methods.
Results
In 2nd group, mild and moderate course of PTSD among women were occurred in 2.0 (χ2 = 0.86, p = 0.001) and 2.2 (χ2 = 0.46, p = 0.023) times more often than in male. While severe and extreme course of PTSD in male of 2nd group were recorded in 1.6 (χ2 = 0.16, p = 0.033) and 1.8 (χ2 = 0.99, p = 0.006) times more often than in female patients.
Conclusions
Examination of patients found that, men have a greater resistance to the risk of developing a disorder in the long term in response to stressors than women, but when the disorder develops, men tend to have more severe manifestations. In women, in the long term after severe mental trauma, the risk of developing PTSD is higher, but the intensity of clinical and psychological manifestations of the disorder is less pronounced.
Registration
The study was carried out in accordance with the plan of research works at the Petro Mohyla Black Sea National University (Adress: 68 Desantnykiv St, 10, Mykolaiv, Ukraine, 54000) on the topic: “Clinical-pathogenetic justification of the system of primary and secondary prevention of the most socially significant chronic non-infectious diseases of internal organs”, state registration number 0120U101641.
Date of registration: 17.03.2021
Duration of research: 03.2021-12.2024
Identification and Phylogeny of Fusarium falciforme causing Potato Dry rot, its Silver Nanoparticles Synthesis, Characterization and Use against Bacterial Pathogens
Authors: Shah Syed Haseeb , Shan Xiaoliang , Baig Sofia , Zhao Hongwei , Siddique Maria , Ismail Bushra , Shahzadi Irum , Bilal Muhammad Saqib , Nawazish Shamyla , Naz Ishrat , Baig Ayesha 
Published: July 2024

Abstract

Potato tubers collected from different areas showed the prevalence of dry rot with characteristic white mycelia of Fusarium pathogen. Fusarium species on diseased tubers were isolated based on morphological features. 18S-ITS based analysis followed by Phylogenetic tree constructed using TEF1-α identified Fusarium isolates as Fusarium verticilloides, Fusarium soloni, Fusarium oxysporum and Fusarium falciforme. According to our knowledge, this study is the first report of occurrence of Fusarium falciforme causing dry rot on potato tubers in Pakistan. The pathogenicity test confirmed the reappearance of dry rot symptoms with Fusarium falciforme on potato tuber. Similarly, the formation of Fusarium falciforme Ag NPs was confirmed using UV, XRD, FTIR and SEM. The synthesized Ag NPs showed color change with Fusarium falciforme and accordingly UV peak was observed at 430 nm. The XRD revealed Ag based specific angles at 36.14°, 44.26°, 64.42° and 77.44° corresponding to face cubic structure. Similarly, FTIR band absorption at 1413 cm1, 1041 cm1 and 690 cm1 ascribed the presence of various biomolecules with O-H and N-H stretching vibrations based on Fusarium falciforme Ag NPs synthesis. SEM indicated the synthesized Ag NPs and EDS analysis showed the presence of Ag in NPs. Maximum zone of inhibition with Fusarium falciforme Ag NPs was observed against Pseudomonas aeruginosa, Escherichia coli, Pseudomonas syringae and Staphylococcus aureus at 0.05 LSD significance.
Chaos-Driven Encryption Algorithm Integrated Logistic Chua Map for Secure Medical Image Communication
Authors: Baowidan Souad Ahmad 
Published: July 2024

Abstract

The use of medical imaging as an effective means of diagnosing diseases has become crucial in the recent past. As all these images are communicated through networks, it’s crucial to provide sufficient protection against unauthorized access. There are several ways in which these images can be protected, and encryption is among some of the best methods available. Encryption algorithms typically involve two primary steps: confusion and diffusion, making it secure and safe. This study proposes a new chaos-based encryption algorithm accompanied by the novel Logistic-Chua Map to maintain privacy of medical images transmission through digital media. Thus, based on the characteristics of the LC Map, a robust Substitution box (S-box) with parameters a = 2.15,b = 0.08,c = 0.03, and r ranging from 0.5 to 5.5. generated by means of the proposed Algorithm. The first algorithm searches for these parameters systematically and strived for an S-box which provides increase in cryptographic strength by means of non-linear substitutions. The S-box is used in the second algorithm to encrypt images with medical data, with 8-bytes key size and the block size of 16 × 16. The encryption process is done via pixel-wise and block-wise substitution, which ensures that there is enough diffusion and confusion. These encrypted images are tested for statistical properties of the data, sensitivity to initial conditions, and against various attacks. The results highlighted that the proposed scheme is effective in protecting medical images and a more efficient solution of secure transmission of medical images.
An Ultra-Fast and Precise Automatic Design Framework for Predicting and Constructing High-Performance Shallow-Trench-Isolation LDMOS Device
Authors: Xu Chenggang , Tang Hongyu , Zhu Yuxuan , Cheng Yue , Jin Xuanzhi , Gao Dawei , Ma Yitao , Xu Kai 
Published: July 2024

Abstract

Shallow Trench Isolation laterally diffused metal oxide semiconductor (STI LDMOS) is a crucial device for power integrated circuits. In this article, a novel framework that integrates an optimal objective function, Bayesian Optimization (BO) algorithm and Deep Neural Network (DNN) model is proposed to fully realize automatic and optimal design of STI LDMOS devices. On the one hand, given the structure of device, the DNN model in the proposed method can provide the ultra-fast and high-accurate performance estimation including breakdown voltage (BV) and specific on-resistance (Ronsp). The experimental results demonstrate 98.68% prediction accuracy in average for both BV and Ronsp, higher than that of other machine learning (ML) algorithms. On the other hand, to target the specified value of BV and Ronsp, the proposed framework can fully automatically and optimally design the precise device structure that simultaneously achieves the target performance with the optimal figure-of-merit (FOM) of device. Compared to Technology Computer Aided Design (TCAD), there is only 0.002% error in FOM and 2.83% average error in BV and Ronsp. Moreover, the proposed framework is 4000 times more efficient than other conventional frameworks. Thus, this research provides experimental groundwork for constructing an automatic design framework for LDMOS device and opens up new opportunities for accelerating the development of LDMOS device in the future.
Managing risks and harms associated with the use of anabolic steroids: a qualitative study
Authors: Amaral Julio Mario Xerfan do , Kimergård Andreas , Deluca Paolo 
Published: July 2024

Abstract

Background
People using anabolic steroids adopt different strategies to manage risks and harms associated with the use of these substances. We investigated the process of learning and incorporating risk-management strategies (RMS), as well as the events that triggered changes in health behaviour.
Methods
Twenty semi-structured interviews were conducted with anabolic steroid users living in the UK to discuss their RMS (19 males, 1 female; median time of drug use = 9 years). Online interviews were transcribed verbatim and qualitative data was analysed via iterative categorisation.
Results
The RMS were characterised as a continuous cycle of identification, prevention and control of risks and harms. Preventative RMS were more commonly adopted after many years of anabolic steroid use. Changes in life circumstances and adverse health conditions were described as triggers for changes in behaviour, including stop using anabolic steroids.
Conclusion
Our results can be used to support interventions aiming to increase awareness and improve health-related behaviours of people using anabolic steroids. Further studies are required to assess the effectiveness and safety of the RMS adopted by this population.
Differentiated Service Pricing Strategies for Ride-Hailing Considering Rational Inattentive Passengers
Authors: Zhao Chuan-Lin , Sun Yangqi , He Shaosong 
Published: July 2024

Abstract

Considering the ambiguity of passengers’ perception of the real service level of ride-hailing, the heterogeneity of driver and passenger preferences for differentiated service modes, the frictions of driver and passenger matching, and the inter-group network externality caused by the scale of driver and passenger, this paper establishes a bi-level optimization model for the pricing strategies of differentiated services on ride-hailing platforms based on the theory of rational inattention. It explores the pricing mechanism of ride-hailing platforms under two optimization objectives (profit maximization and social welfare maximization) and three service strategies (providing both high and low differentiated services, providing a single low service, and providing a single high service). The upper level aims to maximize the profits of ride-hailing platform or social welfare, with service price and commission rate as decision variables. The lower level constructs a driver-passenger equilibrium choice model based on the theory of rational inattention. The model is solved using a combination of particle swarm optimization (PSO) algorithm and method of successive averages (MSA). The upper level model uses PSO algorithm to obtain differentiated service prices and commission rates, which are transmitted to the lower level. The lower level model uses the MSA to solve, and the obtained matching rate and maximum matching time of the driver are transmitted to the upper level. Numerical examples have verified the effectiveness of the model and algorithm. The results show that when passenger prior beliefs follow a uniform distribution, under three strategies, the platform profit shows a trend of first increasing and then decreasing with the increase of unit information cost. To ensure maximum profit, the platform should disclose the service information of ride-hailing as much as possible, but also maintain the unknownness of ride-hailing services appropriately. When the goal is to maximize social welfare, when the unit information cost is low, compared to providing a single service strategy, differentiated service strategy can better meet the differentiated choices of drivers and passengers, thereby ensuring higher social welfare. As the unit information cost increases, three strategies need to attract rational inattentive passengers to choose ride-hailing services by reducing service prices, thereby improving social welfare. The results can provide references for ride-hailing platforms in formulating pricing strategies for differentiated services.
Experimental Validation of a Novel Solid-Liquid Swirling Flow Reactor for Dense Suspensions
Authors: Holemans Thomas , Hogendoorn Willian , Poelma Christian , De Greef Johan , Vanierschot Maarten 
Published: July 2024

Abstract

Ultrasound Imaging Velocimetry (UIV) is a maturing technique for measuring two-phase flows. It enables measurements of dense suspensions when optical methods fail. This study explores UIV’s applicability to measure the flow field in an Swirling Flow Reactor (SFR) for solid-liquid mixing of dense suspensions. Despite UIV’s historical focus on unidirectional flows like arteries and axisymmetric pipes, this research demonstrates its adaptation to an inherently complex 3D flow field, i.e. a swirling sudden expansion flow in an SFR. Using high-speed plane-wave imaging and correlation averaging techniques, satisfactory velocity profiles are achieved while preserving sufficient temporal information. Firstly, the applicability of UIV in this specific setup is demonstrated by comparing UIV with Stereoscopic Particle Image Velocimetry measurements of a one-phase flow in the SFR. Secondly, several bulk velocities and volume concentrations (up to 50 vol%) are measured with UIV for a two-phase flow of water and 2.3 mm glass beads. A transducer is installed in two orientations and captures all three velocity components when combining the two datasets. A timestep optimization process is implemented to avoid manual fine-tuning of the acquisition frequency. A temporal analysis on the solid’s velocity fields in the SFR reveals dominant frequencies between 1.21–2.42 Hz, similar to those found in one phase flow. The general flow structure of the suspension flow is very similar to the latter, however the addition of particles confines the Central Recirculation Zone (CRZ) to the center. Finally, the implementation of swirl to keep solid-liquid mixtures in suspension in the SFR is experimentally confirmed by this study. According to camera recordings, a uniform suspension is achieved across all volumetric loadings. Quantitative UIV measurements confirm favorable flow structures for mixing, specifically a Coandã Jet Flow that avoids sedimentation. The concentration of solids in an SFR can even be increased up to 50 vol% while still maintaining a uniform suspension.
Optimal narrowband composite pulses in two-level systems
Authors: Liang Shi-Peng , Shi Zhi-Cheng , Chen Ye-Hong , Song Jie , Xia Yan 
Published: July 2024

Abstract

We propose a protocol to construct narrowband (NB) composite pulses using quantum optimal control in a full-parameter adjustable two-level system. The optimal NB composite pulses are highly sensitive to various types of parameter deviations. The optimal modulation parameters are obtained by minimizing the cost function composed of the weight factor and the expansion coefficients of transition probabilities. In this way, the problem of multi-parameter modulations and incomplete nullification of expansion coefficients can be effectively solved. Furthermore, the NB composite pulses with arbitrary population transfer can be flexibly achieved by only changing the constraint of the cost function, and the current protocol is easily extended to implement passband composite pulses.
Performance and Diversity of Ethiopian Core Tef Germplasm Under Seasonal Conditions
Authors: Tesfa Derejaw 
Published: July 2024

Abstract

Tef is an indigenous and important food, feed, and cash crop for smallholder Ethiopian farmers. Information about the natural genetic variation of the crop would be useful for genetically improving it through breeding. Therefore, the current study was designed to determine the extent and pattern of genetic variability among selected tef core germplasm lines and released Varieties from Ethiopia, using morphological traits. A total of 81 tef genotypes were field- evaluated for 17 morphological traits using a 9 × 9 simple lattice designs at Debre Zeit during the 2021 main cropping season and off-season. Among the assessed traits, only a few showed significant differences among the genotypes. Specifically, these traits were thousand seed weight and fertile tiller number in the main season, and peduncle length and number of fertile tillers in the off-season. Cluster analysis grouped the 81 tef genotypes into four clusters, each consisting of 15 to 31 genotypes. Principal component analysis indicated that approximately 71% of the gross variance among the tested genotypes could be explained by six principal components with eigenvalues greater than one. In general, the study revealed highly significant genetic distances between clusters 1 and 2. This suggests that selecting tef materials from these clusters for a cross-breeding program would likely be beneficial.
miR-1204 Positioning in 8q24.21 Involved in the Tumorigenesis of Colorectal Cancer by Targeting MASPIN
Authors: Tian Simeng , Chen Meilin , Jing Wanting , Meng Qinghui , Wu Jie 
Published: July 2024

Background:
Colorectal cancer remains to be the third leading cause of cancer mortality
rates. Despite the diverse effects of the miRNA cluster located in PVT1 of 8q24.21 across various
tumors, the specific biological function in colorectal cancer has not been clarified.

Methods:
The amplification of the miR-1204 cluster was analyzed with the cBioPortal database,
while the expression and survival analysis of the miRNAs in the cluster were obtained from several
GEO databases of colorectal cancer. To investigate the functional role of miR-1204 in colorectal
cancer, overexpression and silencing experiments were performed by miR-1204 mimic and inhibitor
transfection in colorectal cancer cell lines, respectively. Then, the effects of miR-1204 on
cell proliferation were assessed through CCK-8, colony formation, and Edu assay. In addition, cell
migration was evaluated using wound healing and Transwell assay. Moreover, candidate genes
identified through RNA sequencing and predicted databases were identified and validated using
PCR and western blot. A Dual-luciferase reporter experiment was conducted to identify MASPIN
as the target gene of miR-1204.

Results:
In colorectal cancer, the miR-1204 cluster exhibited high amplification, and the expression
levels of several cluster miRNAs were also significantly increased. Furthermore, miR-1204
was found to be significantly associated with disease-specific survival according to the analysis of
GSE17536. Functional experiments demonstrated that transfection of miR-1204 mimic or inhibitor
could enhance or decrease cancer cell proliferation and migration. MASPIN was identified as a
target of miR-1204. Additionally, the overexpression of MASPIN partially rescued the effect of
miR-1204 mimics on tumorigenic abilities in LOVO cells.

Conclusion:
miR-1204 positioning in 8q24.21 promotes the proliferation and migration of colorectal
cancer cells by targeting MASPIN.
A Systematic Review of the Anti-seizure and Antiepileptic Effects and Mechanisms of Piperine
Authors: Rahimi-Dehkordi Nasim , Heidari-Soureshjani Saeid , Rostamian Sahar 
Published: July 2024

Introduction and Aim:
Seizures due to epilepsy in any form cause a wide range of
problems in a patient's physical, psychological, and social health. This study aimed to investigate
piperine's anti-seizure and antiepileptic effects and mechanisms.

Methods:
In this systematic review study, which was conducted according to the principles of
PRISMA 2020, the initial search was conducted on November 2, 2023, using EndNote software.
Various databases such as PubMed, Cochrane Library, Web of Science, Embase, and Scopus were
searched using specific keywords. After screening the articles, a form was designed according to
the objectives of the study, and the information related to the included articles was entered in the
form, and the studies were reviewed.

Results:
Piperine showed its antiepileptic activity by affecting the brain's antioxidant, anti-inflammatory,
and anti-apoptotic activity. It also, by modulating brain-derived neurotrophic factor (BDNF)
and gamma-aminobutyric acid (GABA)ergic activity, can control seizures. In addition, piperine
can help treat seizures and epilepsy by elevating 5-HT levels in the brain, modulating astrocyte
and microglia function, modulatory effects on Ca2+ and NA+ channels, increasing antiepileptic
drugs bioavailability and influencing protein and gene expression.

Conclusion:
In vivo and in vitro studies showed beneficial effects on treating epilepsy. Although
clinical studies also showed similar results, these needed to be increased, and more clinical studies
needed to be designed in this field.
Simulation and Analysis of Pressure Waves in Flow Channels of Axial and Radial Gas Wave Ejectors
Authors: Haoran Li , Yiming Zhao , Dapeng Hu 
Published: July 2024

Introduction:
As an efficient energy transfer technology, the gas wave ejector (GWE)
holds several patents poised to address the challenges of low-carbon energy. These patents find applications
in numerous fields. Traditional axial-flow GWE patents encounter limitations under certain
application conditions, whereas radial-flow GWE patents offer an effective solution to these
issues. However, the mechanisms behind the performance differences between these two types of
GWEs have not yet been studied.

Objective:
Since pressure waves are central to energy transfer in wave rotors, this study analyzes the
coupling effects of centrifugal forces and pressure waves. By examining the differences in pressure
wave intensity and propagation velocity within two types of wave rotor channels, the mechanisms
underlying the performance disparities are elucidated.

Method:
Fluent was utilized for numerical simulations, and Response Surface Methodology was
employed to model the influence of various factors.

Result and Discussion:
It can be observed that the propagation velocity and intensity of pressure
waves changed under the influence of centrifugal forces. The propagation velocities of S1 and E2,
which propagate in the same direction as the fluid flow within the rotor, increase 9% and 32% respectively,
whereas the propagation speed of E1, which propagates in the opposite direction of the
fluid flow, decreases 15%. Regarding the intensity of each pressure wave, the coupling effect of
centrifugal force resulted in an increase of 1.04 to 2.55 kPa. This paper is the first to fit a relational
expression for the speed differential of pressure wave propagation within axial and radial flow channels,
correlating the main pressure wave velocities (S1, E1, E2) with flow channel length, rotational
speed, compression ratio, and expansion ratio, thus providing a reference for GWE design and analysis.
Through analysis of variance and significance tests, it is evident that each parameter significantly
contributes to the fitting degree of the pressure wave propagation velocity difference (p < 0.01). Furthermore,
the inadequacy test (F-value=2.36~3.56) suggests a low level of discrepancy.

Conclusion:
The fundamental reason for the performance disparity between the two types of gas
wave ejectors (GWE) lies in the discrepancies in pressure wave intensity and propagation velocity
resulting from centrifugal force effects. Based on the fitted relationships, theoretical foundations can
be provided for subsequent wave rotor design and performance analysis. For example, the differences
in pressure wave propagation speed can inform the design and analysis of corresponding pressure
ports.