bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of a Rewards-Based Incentive Program on Promoting Fruit and Vegetable Purchases
Authors: Phipps Etienne J. , Braitman Leonard E. , Stites Shana D. , Singletary S. Brook , Wallace Samantha L. , Hunt Lacy , Axelrod Saul , Glanz Karen , Uplinger Nadine 
Published: March 2014

Objectives. We assessed the impact of a rewards-based incentive program on fruit and vegetable purchases by low-income families. Methods. We conducted a 4-phase prospective cohort study with randomized intervention and wait-listed control groups in Philadelphia, Pennsylvania, in December 2010 through October 2011. The intervention provided a rebate of 50% of the dollar amount spent on fresh or frozen fruit and vegetables, reduced to 25% during a tapering phase, then eliminated. Primary outcome measures were number of servings of fruit and of vegetables purchased per week. Results. Households assigned to the intervention purchased an average of 8 (95% confidence interval [CI] = 1.5, 16.9) more servings of vegetables and 2.5 (95% CI = 0.3, 9.5) more servings of fruit per week than did control households. In longitudinal price-adjusted analyses, when the incentive was reduced and then discontinued, the amounts purchased were similar to baseline. Conclusions. Investigation of the financial costs and potential benefits of incentive programs to supermarkets, government agencies, and other stakeholders is needed to identify sustainable interventions.
Early Life Conditions, Adverse Life Events, and Chewing Ability at Middle and Later Adulthood
Authors: Listl Stefan , Watt Richard G. , Tsakos Georgios 
Published: March 2014

Objectives. We sought to determine the extent to which early life conditions and adverse life events impact chewing ability in middle and later adulthood. Methods. Secondary analyses were conducted based on data from waves 2 and 3 of the Survey of Health, Ageing, and Retirement in Europe (SHARE), collected in the years 2006 to 2009 and encompassing information on current chewing ability and the life history of persons aged 50 years or older from 13 European countries. Logistic regression models were estimated with sequential inclusion of explanatory variables representing living conditions in childhood and adverse life events. Results. After controlling for current determinants of chewing ability at age 50 years or older, certain childhood and later life course socioeconomic, behavioral, and cognitive factors became evident as correlates of chewing ability at age 50 years or older. Specifically, childhood financial hardship was identified as an early life predictor of chewing ability at age 50 years or older (odds ratio = 1.58; 95% confidence interval = 1.22, 2.06). Conclusions. Findings suggest a potential enduring impact of early life conditions and adverse life events on oral health in middle and later adulthood and are relevant for public health decision-makers who design strategies for optimal oral health.
Non-Diversifiable Volatility Risk and Risk Premiums at Earnings Announcements
Authors: Barth Mary E. , So Eric C. 
Published: March 2014

ABSTRACT
This study seeks to determine whether earnings announcements pose non-diversifiable volatility risk that commands a risk premium. We find that investors anticipate some earnings announcements to convey news that increases market return volatility and pay a premium to hedge this non-diversifiable risk. In particular, we find evidence of risk premiums embedded in prices of firms' traded options that are significantly positively associated with the extent to which the firms' earnings announcements pose non-diversifiable volatility risk. In addition, we find that volatility risk premiums are concentrated among bellwether firms and result in predictable variation in option straddle returns around earnings announcements. Taken together, our findings show that some earnings announcements pose non-diversifiable volatility risk that commands a risk premium.
JEL Classifications: M41; G12; G13; G14
Infant Body Composition and Adipokine Concentrations in Relation to Maternal Gestational Weight Gain
Authors: Estampador Angela C. , Pomeroy Jeremy , Renström Frida , Nelson Scott M. , Mogren Ingrid , Persson Margareta , Sattar Naveed , Domellöf Magnus , Franks Paul W. 
Published: March 2014

OBJECTIVE
To investigate associations of maternal gestational weight gain and body composition and their impact on offspring body composition and adipocytokine, glucose, and insulin concentrations at age 4 months.

RESEARCH DESIGN AND METHODS
This was a prospective study including 31 mother-infant pairs (N = 62). Maternal body composition was assessed using doubly labeled water. Infant body composition was assessed at 4 months using air displacement plethysmography, and venous blood was assayed for glucose, insulin, adiponectin, interleukin-6 (IL-6), and leptin concentrations.

RESULTS
Rate of gestational weight gain in midpregnancy was significantly associated with infant fat mass (r = 0.41, P = 0.03); rate of gestational weight in late pregnancy was significantly associated with infant fat-free mass (r = 0.37, P = 0.04). Infant birth weight was also strongly correlated with infant fat-free mass at 4 months (r = 0.63, P = 0.0002). Maternal BMI and maternal fat mass were strongly inversely associated with infant IL-6 concentrations (r = −0.60, P = 0.002 and r = −0.52, P = 0.01, respectively). Infant fat-free mass was inversely related to infant adiponectin concentrations (r = −0.48, P = 0.008) and positively correlated with infant blood glucose adjusted for insulin concentrations (r = 0.42, P = 0.04). No significant associations for leptin were observed.

CONCLUSIONS
Timing of maternal weight gain differentially impacts body composition of the 4-month-old infant, which in turn appears to affect the infant’s glucose and adipokine concentrations.
3D loss and heat analysis at the end region of 4-poles 1150 MW nuclear power turbine generator
Authors: Zhou Guang-Hou , Han Li , Fan Zhen-Nan , Liao Yong , Huang Song 
Published: March 2014

Abstract
To study the principle of loss and heat at the end region of large 4-poles nuclear power turbine generator, 3D transient electromagnetic field and 3D steady temperature field finite element (FE) models of the end region are established respectively. Considering the factors such as rotor motion, core non-linearity and time-varying of electromagnetic field, the anisotropic heat conductivity and different heat dissipation conditions of stator end region, a 50 Hz, 1150 MW, 4-poles nuclear power turbine generator is investigated. The loss and heat at the generator end region are calculated respectively at no-load and rated-load, and the calculation results are compared with the test data. The result shows that the calculation model is accurate and the generator design is suitable. The method is valuable for the research of loss and heat at the end region of large 4-poles nuclear power turbine generator and the improvement of the generator’s operation stability. The method has been applied successfully for the design of the larger nuclear power turbine generators
‘Love Does Not Delight in Evil, but Rejoices With the Truth.’ A Theological and Pastoral Reflection On My Journey Away From A Homosexual Identity
Authors: Doherty Sean 
Published: March 2014

Abstract
This article offers theological reflection on the author’s experience, initially as a celibate gay person and subsequently as someone who has chosen not to be defined as gay and who has married. It argues that faithfulness to the classic Christian teaching about sex and marriage is liberating rather than homophobic, and that the contemporary cultural tendency to conflate sexual desire with identity bears at least some of the blame for the gay experience of marginalisation. This conflation must be questioned. The article concludes by relating this to Dietrich Bonhoeffer’s critique of anthropocentric construals of ‘love’.
The Center Of A Generalized Effect Algebra
Authors: Foulis D. J. , Pulmannová S. 
Published: March 2014

AbstractIn this article, we study the center of a generalized effect algebra (GEA), relate it to the exocenter, and in case the GEA is centrally orthocomplete (a COGEA), relate it to the exocentral cover system. Our main results are that the center of a COGEA is a complete boolean algebra and that a COGEA decomposes uniquely as the direct sum of an effect algebra (EA) that contains the center of the COGEA and a complementary direct summand in which no nonzero direct summand is an EA.
Cocentralizing Generalized Derivations On Multilinear Polynomial On Right Ideals Of Prime Rings
Authors: Filippis Vincenzo De , Dhara Basudeb 
Published: March 2014

AbstractLet R be a prime ring with Utumi quotient ring U and with extended centroid C, I a non-zero right ideal of R ƒ (x1… xn) a multilinear polynomial over C which is not central valued on R and G, H two generalized derivations of R. Suppose that G(ƒ (r)) ƒ (r)- ƒ (r)H(ƒ (r)) ∈ C, for all r =(r1. there exist a; b; p ∈ U and α C such that G(x)= ax + [p, x] and H(x) = bx, for all x ∈ R, and (a-b)I=(0)=(a + p- α)I;2. R satisfies s3. R satisfies s4. R satisfies s5. there exists e(a) [ƒ (x(b) char (R) = 2 and s(c) [ƒ (x
On Totally Contact Umbilical Contact CR-Lightlike Submanifolds Of Indefinite Sasakian Manifolds
Authors: Gogna Manish , Kumar Rakesh , Nagaich R. K. 
Published: March 2014

AbstractAfter brief introduction, we prove that a totally contact umbilical CR- lightlike submanifold is totally contact geodesic. We obtain a necessary and sufficient condition for a CR-lightlike submanifold to be an anti-invariant submanifold. Finally, we characterize a contact CR-lightlike submanifold of indefinite Sasakian manifold to be a contact CR-lightlike product
Change and Its Repercussions for the Banking Industry
Authors: Adizes Ichak Kalderon 
Published: March 2014

Abstract
Changes have always existed but their speed and frequency have become rather apparent. Changes are present in all areas of life, but here we focus on those happening in the banking industry. Banks are undergoing revolutionary changes and they must change or perish in their present form. The article explains why banks must change and what are the threats to both asset and liability sides they would face otherwise. Changes result in modifications of strategies, organizations and management. The article concludes that banks that are the most flexible and able to adapt will win the day.
A note on the multiplication of sparse matrices
Authors: Borna Keivan , Fard Sohrab 
Published: March 2014

AbstractWe present a practical algorithm for multiplication of two sparse matrices. In fact if A and B are two matrices of size n with m 1 and m 2 non-zero elements respectively, then our algorithm performs O(min{m 1 n, m 2 n, m 1 m 2}) multiplications and O(k) additions where k is the number of non-zero elements in the tiny matrices that are obtained by the columns times rows matrix multiplication method. Note that in the useful case, k ≤ m 2 n. However, in Proposition 3.3 and Proposition 3.4 we obtain tight upper bounds for the complexity of additions. We also study the complexity of multiplication in a practical case where non-zero elements of A (resp. B) are distributed independently with uniform distribution among columns (resp. rows) of them and show that the expected number of multiplications is O(m 1 m 2/n). Finally a comparison of number of required multiplications in the naïve matrix multiplication, Strassen’s method and our algorithm is given.
Spatial aspects of european airports’ partial factor productivity
Authors: Pavlyuk Dmitry 
Published: March 2014

Abstract
This research is devoted to discovering of spatial effects in European airports’ partial factor productivity (PFP). A set of study PFP indicators includes infrastructural (air transport movements per runway), labour (workload units per employee), and financial (revenue and profit per workload unit) ratios. We utilised a number of appropriate statistical tests (Moran’s I., Geary’s C., Mantel test, and spatial auto-regression) for revelation of spatial relationships between PFP indicator’s values. The tests were separately applied to samples of Spanish (2009-2010) and UK airports (2011-2012) and provided evidences of significant spatial effects in data.
Experimental results of elevation change analysis in the Antarctic ice sheet using DEMs from ERS and ICESat data
Authors: Gu Zhenxiong , Feng Tiantian , Scaioni Marco , Wu Hangbin , Liu Jun , Tong Xiaohua , Li Rongxing 
Published: March 2014

AbstractThe aim of this research is to investigate elevation changes in the Antarctic ice sheet by comparing two digital elevation models (DEMs) derived from satellite altimetry data covering the period 1994–2004. Data collected by ERS-1/2 satellite radar altimetry and by NASA GLAS/ICESat laser altimetry were used. After preprocessing and resampling at the same spatial resolution, both DEMs were compared in a pointwise fashion and elevation differences computed, which consisted of three main components: (1) actual elevation change, (2) errors in the original data sources and (3) interpolation errors that arose during generation of the DEMs. The objectives of the research were to analyze errors, attempt to mitigate systematic effects when possible, and draw some conclusions about the limitations of using DEM products for computing ice-sheet elevation change at local and continental scales. A linear correlation between errors in elevation differences and surface slope was found in the slope range [0°, 0.4°]. This trend was interpreted as residual slope-induced systematic error and compensated for. Finally, an elevation difference map of the Antarctic ice sheet was generated. Analysis of the derived elevation changes at the drainage basin was also made. Results are compared with the results of previous studies.
Selection of an optimal method for the preparation of dual loaded flavono polymeric nanoparticle using analytical hierarchy process
Authors: Chinnamaruthu Senthil Kumar , Sellappan Mohan 
Published: March 2014

In this study, analytical hierarchy process was used to select an optimal method for the preparation of dual loaded flavono polymeric nanoparticles. Analytical hierarchy process involves structuring multiple choice criteria into a hierarchy, assessing the relative importance of criteria, comparing alternatives for each criterion and determining an overall ranking of the alternatives. Hierarchy model was developed with the goal in the first level, 10 criteria in the second level and methods for the preparation of polymeric nanoparticles in the third level. To assess the relative importance of criteria, all criteria were compared with each other using Saatys scale. To compare the methods, all the methods for the preparation of polymeric nanoparticles were compared with each other for each criterion using Saatys scale, which leads to the formation of pair-wise comparison matrixes and consistency ratio was calculated for the each pair-wise comparison matrix. The study result showed that the consistency ratio of each pair-wise comparison matrix were well within acceptable limits. Of 10 criteria, reproducible results received the maximum overall priority weight followed by desirable size. Of 10 methods, nanoprecipitation method received the maximum overall priority weight followed by supercritical fluid technology. Analytical hierarchy process has identified reproducible results as criteria preference and nanoprecipitation as an optimal method for the preparation of dual loaded flavono polymeric nanoparticles. The study concludes that the analytical hierarchy process has played a vital role in selecting an optimal method for the preparation of dual loaded flavono polymeric nanoparticles.DOI: http://dx.doi.org/10.3329/icpj.v3i4.18264 International Current Pharmaceutical Journal, March 2014, 3(4): 247-253
Evaluation of anaphylactic reaction as an adverse event for perindopril erbumine tablets
Authors: Krishnan Kiran , Krishnasamy Kathiresan 
Published: March 2014

Perindopril erbumine is a tert-butylamine salt of perindopril used in the treatment of stable coronary artery disease and hypertension. The present study was aimed to evaluate the anaphylactic reaction as an adverse event for perindopril erbumine tablets. Electronic extraction of data from the safety database for this report includes all cases of anaphylactic reaction where perindopril was a primary or co-suspect drug. The study result have shown that there were overall 205 case reports for perindopril in the database, of which 200 cases were assessed as (potentially) perindopril and 05 were assessed as non-perindopril product. From the 200 case reports, 141 were serious and 59 were non-serious. Out of the 141 serious cases, 137 cases were medically confirmed while remaining 04 cases were consumer reports. Of the total 205 case reports there were five cases wherein the patient experienced anaphylactic reaction. The study concludes that three out of five cases entered in the drug safety database suggestive of a possible association between perindopril and anaphylactic reaction.DOI: http://dx.doi.org/10.3329/icpj.v3i4.18265 International Current Pharmaceutical Journal, March 2014, 3(4): 254-258
Differential Role of Th1 and Th2 Cytokines in Autotoxicity Driven by CD19-Specific Second-Generation Chimeric Antigen Receptor T Cells in a Mouse Model
Authors: Cheadle Eleanor J. , Sheard Victoria , Rothwell Dominic G. , Bridgeman John S. , Ashton Garry , Hanson Vivien , Mansoor A. Wasat , Hawkins Robert E. , Gilham David E. 
Published: March 2014

Abstract
T cells engrafted with chimeric AgRs (CAR) are showing exciting potential for targeting B cell malignancies in early-phase clinical trials. To determine whether the second-generation CAR was essential for optimal antitumor activity, two CD28-based CAR constructs targeting CD19 were tested for their ability to redirect mouse T cell function against established B cell lymphoma in a BALB/c syngeneic model system. T cells armed with either CAR eliminated A20 B cell lymphoma in vivo; however, one construct induced a T cell dose-dependent acute toxicity associated with a raised serum Th1 type cytokine profile on transfer into preconditioned mice. Moreover, a chronic toxicity manifested as granuloma-like formation in spleen, liver, and lymph nodes was observed in animals receiving T cells bearing either CD28 CAR, albeit with different kinetics dependent upon the specific receptor used. This phenotype was associated with an expansion of CD4+CAR+ T cells and CD11b+Gr-1+ myeloid cells and increased serum Th2-type cytokines, including IL-10 and IL-13. Mouse T cells engrafted with a first-generation CAR failed to develop such autotoxicity, whereas toxicity was not apparent when T cells bearing the same receptors were transferred into C57BL/6 or C3H animals. In summary, the adoptive transfer of second-generation CD19-specific CAR T cells can result in a cell dose–dependent acute toxicity, whereas the prolonged secretion of high levels of Th2 cytokines from these CAR T cells in vivo drives a granulomatous reaction resulting in chronic toxicity. Strategies that prevent a prolonged Th2-cytokine biased CAR T cell response are clearly warranted.
Functional Characterization of Ocular-Derived Human Alphaherpesvirus Cross-Reactive CD4 T Cells
Authors: Ouwendijk Werner J. D. , Geluk Annemieke , Smits Saskia L. , Getu Sarah , Osterhaus Albert D. M. E. , Verjans Georges M. G. M. 
Published: March 2014

Abstract
Intraocular varicella-zoster virus (VZV) and HSV type 1 (HSV-1) infections cause sight-threatening uveitis. The disease is characterized by an intraocular inflammatory response involving herpesvirus-specific T cells. T cell reactivity to the noncausative human alphaherpesvirus (αHHV) is commonly detected in the affected eyes of herpetic uveitis patients, suggesting the role of cross-reactive T cells in the disease. This study aimed to identify and functionally characterize intraocular human alphaherpesvirus cross-reactive T cells. VZV protein immediate early 62 (IE62), which shares extensive homology with HSV ICP4, is a previously identified T cell target in VZV uveitis. Two VZV-specific CD4 T cell clones (TCC), recovered from the eye of a VZV uveitis patient, recognized the same IE62918–927 peptide using different TCR and HLA-DR alleles. The IE62918–927 peptide bound with high affinity to multiple HLA-DR alleles and was recognized by blood-derived T cells of 5 of 17 HSV-1/VZV-seropositive healthy adults but not in cord blood donors (n = 5). Despite complete conservation of the IE62 epitope in the orthologous protein ICP4 of HSV-1 and HSV-2, the TCC recognized VZV and HSV-1– but not HSV-2–infected B cells. This was not attributed to proximal epitope-flanking amino acid polymorphisms in HSV-2 ICP4. Notably, VZV/HSV-1 cross-reactive CD4 T cells controlled VZV but not HSV-1 infection of human primary retinal pigment epithelium (RPE) cells. In conclusion, we report on the first VZV/HSV-1 cross-reactive CD4 T cell epitope, which is HLA-DR promiscuous and immunoprevalent in coinfected individuals. Moreover, ocular-derived peptide-specific CD4 TCC controlled VZV but not HSV-1 infection of RPE cells, suggesting that HSV-1 actively inhibits CD4 T cell activation by infected human RPE cells.
ORMDL3 Transgenic Mice Have Increased Airway Remodeling and Airway Responsiveness Characteristic of Asthma
Authors: Miller Marina , Rosenthal Peter , Beppu Andrew , Mueller James L. , Hoffman Hal M. , Tam Arvin B. , Doherty Taylor A. , McGeough Matthew D. , Pena Carla A. , Suzukawa Maho , Niwa Maho , Broide David H. 
Published: March 2014

Abstract
Orosomucoid-like (ORMDL)3 has been strongly linked with asthma in genetic association studies. Because allergen challenge induces lung ORMDL3 expression in wild-type mice, we have generated human ORMDL3 zona pellucida 3 Cre (hORMDL3zp3-Cre) mice that overexpress human ORMDL3 universally to investigate the role of ORMDL3 in regulating airway inflammation and remodeling. These hORMDL3zp3-Cre mice have significantly increased levels of airway remodeling, including increased airway smooth muscle, subepithelial fibrosis, and mucus. hORMDL3zp3-Cre mice had spontaneously increased airway responsiveness to methacholine compared to wild-type mice. This increased airway remodeling was associated with selective activation of the unfolded protein response pathway transcription factor ATF6 (but not Ire1 or PERK). The ATF6 target gene SERCA2b, implicated in airway remodeling in asthma, was strongly induced in the lungs of hORMDL3zp3-Cre mice. Additionally, increased levels of expression of genes associated with airway remodeling (TGF-β1, ADAM8) were detected in airway epithelium of these mice. Increased levels of airway remodeling preceded increased levels of airway inflammation in hORMDL3zp3-Cre mice. hORMDL3zp3-Cre mice had increased levels of IgE, with no change in levels of IgG, IgM, and IgA. These studies provide evidence that ORMDL3 plays an important role in vivo in airway remodeling potentially through ATF6 target genes such as SERCA2b and/or through ATF6-independent genes (TGF-β1, ADAM8).