bluuebunny/crossref_metadata_2025_split huggingface dataset:
3DMOUSEneST: a volumetric label-free imaging method evaluating embryo–uterine interaction and decidualization efficacy
Authors: Savolainen Audrey , Kapiainen Emmi , Ronkainen Veli-Pekka , Izzi Valerio , Matzuk Martin M. , Monsivais Diana , Prunskaite-Hyyryläinen Renata 
Published: July 2024

ABSTRACT
Effective interplay between the uterus and the embryo is essential for pregnancy establishment; however, convenient methods to screen embryo implantation success and maternal uterine response in experimental mouse models are currently lacking. Here, we report 3DMOUSEneST, a groundbreaking method for analyzing mouse implantation sites based on label-free higher harmonic generation microscopy, providing unprecedented insights into the embryo–uterine dynamics during early pregnancy. The 3DMOUSEneST method incorporates second-harmonic generation microscopy to image the three-dimensional structure formed by decidual fibrillar collagen, named ‘decidual nest’, and third-harmonic generation microscopy to evaluate early conceptus (defined as the embryo and extra-embryonic tissues) growth. We demonstrate that decidual nest volume is a measurable indicator of decidualization efficacy and correlates with the probability of early pregnancy progression based on a logistic regression analysis using Smad1/5 and Smad2/3 conditional knockout mice with known implantation defects. 3DMOUSEneST has great potential to become a principal method for studying decidual fibrillar collagen and characterizing mouse models associated with early embryonic lethality and fertility issues.
Does sex matter in the cheetah? Insights into the skeletal muscle of the fastest land animal
Authors: Kohn Tertius A. , Knobel Samantha , Donaldson Byron , van Boom Kathryn M. , Blackhurst Dee M. , Peart James M. , Jensen Jørgen , Tordiffe Adrian S. W. 
Published: July 2024

ABSTRACT
The cheetah is considered the fastest land animal, but studies on their skeletal muscle properties are scarce. Vastus lateralis biopsies, obtained from male and female cheetahs as well as humans, were analysed and compared for fibre type and size, and metabolism. Overall, cheetah muscle had predominantly type IIX fibres, which was confirmed by the myosin heavy chain isoform content (mean±s.d. type I: 17±8%, type IIA: 21±6%, type IIX: 62±12%), whereas human muscle contained predominantly type I and IIA fibres (type I: 49±14%, type IIA: 43±8%, type IIX: 7±7%). Cheetahs had smaller fibres than humans, with larger fibres in the males compared with their female counterparts. Citrate synthase (16±6 versus 28±7 µmol min−1 g−1 protein, P&lt;0.05) and 3-hydroxyacyl co-enzyme A dehydrogenase (30±11 versus 47±15 µmol min−1 g−1 protein, P&lt;0.05) activities were lower in cheetahs than in humans, whereas lactate dehydrogenase activity was 6 times higher in cheetahs (2159±827 versus 382±161 µmol min−1 g−1 protein, P&lt;0.001). The activities of creatine kinase (4765±1828 versus 6485±1298, P&lt;0.05 µmol min−1 g−1 protein) and phosphorylase (111±29 versus 216±92 µmol min−1 g−1 protein) were higher in humans, irrespective of the higher type IIX fibres in cheetahs. Superoxide dismutase and catalase, markers of antioxidant capacity, were higher in humans, but overall antioxidant capacity was higher in cheetahs. To conclude, fibre type, fibre size and metabolism differ between cheetahs and humans, with limited differences between the sexes.
Drosophila melanogaster sperm turn more oxidative in the female
Authors: Wetzker Cornelia , Froschauer Christin , Massino Christian , Reinhardt Klaus 
Published: July 2024

ABSTRACT
Males and females of many species store sperm for extended periods. During storage, sperm are predicted to undergo cellular and functional changes, especially towards glycolytic energy metabolism because oxygen radicals derived from oxidative phosphorylation can affect sperm motility and fertilisation ability. However, not all species can use both major energy metabolism pathways. Here, we examined the fruit fly Drosophila melanogaster and asked whether sperm metabolism can be fuelled by both glycolysis and oxidative phosphorylation, and to what extent metabolism changes during storage. Inhibiting glycolysis in vitro led to a more oxidative state of sperm; inhibiting oxidative phosphorylation increased the glycolytic component, assessed by multi-photon autofluorescence lifetime imaging (FLIM) of NAD(P)H. We further examined sperm in male and female sperm storage organs using FLIM of NAD(P)H and FAD. In intact storage organs, we found that, unexpectedly, (i) sperm were more oxidative in females than in males, and (ii) oxidative phosphorylation increased with storage duration in females. Our observation that the relative contribution of the two major energy metabolic pathways in D. melanogaster sperm differs in males and females and over storage time has important evolutionary implications.
Nonadaptive Stochastic Score Classification and Explainable Half-Space Evaluation
Authors: Ghuge Rohan , Gupta Anupam , Nagarajan Viswanath 
Published: July 2024

Nonadaptive Stochastic Score Classification Sequential testing problems involve a system with several components, each of which is working with some independent probability. The working/failed status of each component can be determined by performing a test, which is usually expensive. So, the goal is to perform tests in a carefully chosen sequence until the overall system status can be evaluated. These problems arise in a variety of applications, such as healthcare, manufacturing, and telecommunication. A common task in these applications is to categorize the system into one of several classes that correspond to the system status being poor, fair, good, excellent, etc. In “Nonadaptive Stochastic Score Classification and Explainable Half-Space Evaluation,” Ghuge, Gupta, and Nagarajan provide the first constant-factor approximation algorithm for this problem. Moreover, the resulting policy is nonadaptive, which results in significant savings in computational time. The authors also validate their theoretical results via computational experiments, where they observe that their algorithm’s cost is on average at most 50% more than an information-theoretic lower bound.
Less is more: surface-lattice-resonance-enhanced aluminum metasurface with giant saturable absorption for a wavelength-tunable Q-switched Yb-doped fiber laser
Authors: Xie Hailun , Gui Lili , Zhou Xiangxiang , Zhou Yue , Xu Kun 
Published: July 2024

Resonant metasurfaces provide a promising solution to overcome the limitations of nonlinear materials in nature by enhancing the interaction between light and matter and amplifying optical nonlinearity. In this paper, we design an aluminum (Al) metasurface that supports surface lattice resonance (SLR) with less nanoparticle filling density but more prominent saturable absorption effects, in comparison to a counterpart that supports localized surface plasmon resonance (LSPR). In detail, the SLR metasurface exhibits a narrower resonance linewidth and a greater near-field enhancement, leading to a more significant modulation depth (9.6%) at a low incident fluence of 25  μJ/cm2. As an application example, we have further achieved wavelength-tunable Q-switched pulse generation from 1020 to 1048 nm by incorporating the SLR-based Al metasurface as a passive saturable absorber (SA) in a polarization-maintaining ytterbium-doped fiber laser. Typically, the Q-switched pulse with a repetition rate of 33.7 kHz, pulse width of 2.1 μs, pulse energy of 141.7 nJ, and signal-to-noise ratio (SNR) of greater than 40 dB at the fundamental frequency can be obtained. In addition, we have investigated the effects of pump power and central wavelength of the filter on the repetition rate and pulse width of output pulses, respectively. In spite of demonstration of only using the Al metasurface to achieve a passive Q-switched fiber laser, our work offers an alternative scheme to build planar, lightweight, and broadband SA devices that could find emerging applications from ultrafast optics to neuromorphic photonics, considering the fast dynamics, CMOS-compatible fabrication, and decent nonlinear optical response of Al-material-based nanoplasmonics.
The role of general practice nurses in supporting people to quit smoking: A qualitative study
Authors: Jongebloed Hannah , Cole Eileen , Dean Emma , Ugalde Anna 
Published: July 2024

Purpose
Encounters with General Practitioners (GPs) have previously been identified as opportune for the delivery of smoking cessation care however the role of nurses in general practice settings is unclear. This study aimed to understand how nurses are providing smoking cessation care in general practice.

Methods
Participants were registered nurses currently working in a general practice setting in Australia, who participated in one-off interviews over Zoom. Interviews were recorded and a thematic analysis was conducted.

Results
Fourteen nurses participated of which 13 (93%) were female. Three themes were evident in the data: 1) Nurses’ current practices in supporting people to quit smoking, 2) The influence of the general practice setting on smoking cessation discussions and 3) The challenges experienced by nurses in providing optimal smoking cessation care. Theme one describes the strategies currently employed by nurses to deliver smoking cessation care such as identifying appropriate clinical scenarios to have smoking cessation conversations with patients. Theme two explores the impact of diversity in the systems, processes, and structures across Australian general practice settings on the support offered by nurses, such as opportunities for ongoing relationships with patients Theme three focuses on ambiguity in nurses’ roles within the practice setting including a lack of clarity for nurses in their roles in delivering smoking cessation care in the general practice setting.

Conclusions
General practice nurses recognise the importance of their role in providing smoking cessation care and consider that general practice settings are ideally positioned to deliver that care. Smoking cessation care provided by nurses varies according to systems and processes within general practice clinics and relationships with general practitioners. Vaping is an emerging issue and nurses are seeking information on how to address this with patients. There is opportunity to support nurses to provide improved smoking cessation care.
Is mechanism of injury associated with outcome in spinal trauma? An observational cohort study from Tanzania
Authors: Ikwuegbuenyi Chibuikem Anthony , Woodfield Julie , Waterkeyn François , Zuckerman Scott L. , Cheserem Beverly , Leidinger Andreas , Lazaro Albert , Shabani Hamisi K. , Härtl Roger , Mangat Halinder S. 
Published: July 2024

Background
Traumatic spinal injury (TSI) is a disease of significant global health burden, particularly in low and middle-income countries where road traffic-related trauma is increasing. This study compared the demographics, injury patterns, and outcomes of TSI caused by road traffic accidents (RTAs) to non-traffic related TSI.

Methods
A retrospective analysis was conducted using a neurotrauma registry from the Muhimbili Orthopaedic Institute (MOI) in Tanzania, a national referral center for spinal injuries. Patient sociodemographic characteristics, injury level, and severity were compared across mechanisms of injury. Neurological improvement, neurological deterioration, and mortality were compared between those sustaining TSI through an RTA versus non-RTA, using univariable and multivariable analyses.

Results
A total of 626 patients were included, of which 302 (48%) were RTA-related. The median age was 34 years, and 532 (85%) were male. RTAs had a lower male preponderance compared to non-RTA causes (238/302, 79% vs. 294/324, 91%, p<0.001) and a higher proportion of cervical injuries (144/302, 48% vs. 122/324, 38%, p<0.001). No significant differences between RTA and non-RTA mechanisms were found in injury severity, time to admission, length of hospital stay, surgical intervention, neurological outcomes, or in-hospital mortality. Improved neurological outcomes were associated with incomplete injuries (AIS B-D), while higher mortality rates were linked to cervical injuries and complete (AIS A) injuries.

Conclusion
Our study in urban Tanzania finds no significant differences in outcomes between spinal injuries from road traffic accidents (RTAs) and non-RTA causes, suggesting the need for equitable resource allocation in spine trauma programs. Highlighting the critical link between cervical injuries and increased mortality, our findings call for targeted interventions across all causes of traumatic spinal injuries (TSI). We advocate for a comprehensive trauma care system that merges efficient pre-hospital care, specialized treatment, and prevention measures, aiming to enhance outcomes and ensure equity in trauma care in low- and middle-income countries.
Efficacy and Safety of Postbiotic Contained Inactivated Lactobacillus reuteri (Limosilactobacillus reuteri) DSM17648 as Adjuvant Therapy in the Eradication of Helicobacter pylori in Adults With Functional Dyspepsia: A Randomized Double-Blind Placebo-Controlled Trial
Authors: Ivashkin Vladimir , Maev Igor , Poluektova Elena , Sinitsa Alexander , Avalueva Elena , Mnatsakanyan Marina , Simanenkov Vladimir , Karpeeva Julia , Kopylova Daria , Kuprina Irina , Kucheryavyy Yury , Lapina Tatiana , Solovyeva Olga , Soom Malle , Cheremushkina Natalia , Maevskaya Evgeniya , Maslennikov Roman 
Published: July 2024

INTRODUCTION:
Increasing the effectiveness of eradication therapy is an important task in gastroenterology. The aim of this study was to evaluate the efficacy and safety of postbiotic containing inactivated (nonviable) Limosilactobacillus (Lactobacillus) reuteri DSM17648 (Pylopass) as adjuvant treatment of Helicobacter pylori eradication in patients with functional dyspepsia (FD).

METHODS:
This randomized, double-blind, placebo-controlled, multicenter, parallel study included H. pylori-positive patients with FD. The postbiotic group received Pylopass 200 mg bid for 14 days in combination with eradication therapy (esomeprazole 20 mg bid + amoxicillin 1,000 mg bid + clarithromycin 500 mg bid for 14 days) and another 14 days after the completion of eradication therapy. The study was registered in the ISRCTN registry (ISRCTN20716052).

RESULTS:
Eradication efficiency was 96.7% for the postbiotic group vs 86.0% for the placebo group (P = 0.039). Both groups showed significant improvements in quality of life and reduction of most gastrointestinal symptoms with no significant differences between groups. The overall number of digestive adverse effects in the postbiotic group was lower than in the placebo group. Serious adverse effects were not registered.

DISCUSSION:
The postbiotic containing inactivated L. reuteri DSM17648 significantly improves the effectiveness of H. pylori eradication therapy in FD and decreases overall number of digestive adverse effects of this therapy.
PENGARUH FATHER ATTACHMENT TERHADAP SELF-DISCLOSURE WANITA DEWASA AWAL DALAM HUBUNGAN ROMANTIS
Authors: Yulianti Dwi Wulan , Hijrianti Udi Rosida 
Published: July 2024

Self-disclosure yang baik sangat diperlukan untuk menjalin hubungan dan interaksi secara sosial maupun dalam hubungan intim. Salah satu faktor yang mempengaruhi seseorang melakukan self-disclosure diantaranya adalah anggota keluarga. Maka dari itu, penelitian ini bertujuan untuk mencari tahu pengaruh father attachment terhadap self-disclosure wanita dewasa dalam hubungan romantis. Penelitian ini menggunakan pendekatan kuantitatif korelasi dengan subjek berjumlah 250 wanita dewasa awal yang berpacaran. Instrumen yang digunakan adalah Inventory of Parent and Peer Attachment (IPPA) dan Self-Disclosure Scale. Analisis data yang digunakan yaitu uji regresi linier sederhana dengan hasil 17.6% kelekatan pada ayah dapat mempengaruhi self-disclosure wanita dewasa awal yang menjalani hubungan romantis. Artinya, semakin tinggi kelekatan yang diberikan, akan semakin tinggi pula self-disclosure yang dilakukan, begitupun sebaliknya.
Remarks on a result of Chen-Cheng
Authors: Lu Zhiqin , Seyyedali Reza 
Published: July 2024

Abstract
In their seminal work, Chen and Cheng proved a priori estimates for the constant scalar curvature metrics on compact Kähler manifolds. They also prove

C

3
,
α

{C}^{3,\alpha }

-estimate for the potential of the Kähler metrics under boundedness assumption on the scalar curvature and the entropy. The goal of this article is to replace the uniform boundedness of the scalar curvature to the

L

p

{L}^{p}

-boundedness of the scalar curvature.
Dual band beam steering antenna using branch line coupler network for higher band applications
Authors: Abhishek Amit , Suraj Priyadarshi 
Published: July 2024

Abstract
A beam-steering fed array antenna has been proposed for radar and mm-Wave applications operating from 22.6 to 26.89 GHz and 30–45 GHz with B.W % of 17.34 % and 40 % respectively having size of 12.11 × 25.58 × 0.8 mm3 (0.96λo × 2.01λo × 0.06λo). For radar, this antenna covers 24.15 GHz as police radar, 24.25–25.25 GHz & 31.8–33.4 GHz as navigation radar, and 33.4–36 GHz as high-resolution radar for airport surveillance. This antenna also covers mm-wave bands for different countries (Brazil-40 GHz, China- 34–42.5 GHz, Mexico- 33 GHz and 37 GHz, and USA- 24 GHz, 37 & 39 GHz). At initial stage, a monopole antenna with DGS has been designed with an operating band of 20.2–31.2 GHz and 36.6–42.2 GHz. Proposed antenna shifts the beam pattern at 90° with each other after exciting each port in alternative order with a scanning angle of ±45°, ±75° & ±180°. Peak gain for 1st band ranges from 7.1 to 9 dBi and for the 2nd band ranges from 8.8 to 10.2 dBi and has a radiation efficiency of 88 %. Other diversity parameters such as ECC, DG, MEG, and isolation get analysed to observe the coupling effects. Design, development, and analysis of all antenna parameters is done by using HFSS 19 platform.
The Ties and Contacts between Ancient Mongolian Nomads and other Asian Civilizations
Authors: Shiirevdorj Serchmaa 
Published: July 2024

Abstract
History is the study of people– specifically how people existed, lived, thought, and created in the past. It is very interesting to study how our ancestors, the nomadic Mongolians, lived on this land and the origin of our great grandparents for generations. Most of the time, people have been interested in the origin of their ancestors since ancient times, and they have explained it mostly through myths and religious views. The Mongolian plateau has been a home to nomads throughout its history. Mongolia is a heartland of nomadic empires that are famous not only in the steppes of Europe and Asia but also in the world. The large river basins and steppes of Mongolia are ideal areas for nomadic livestock farming, and the nomads who conquered these areas became a dominant force in the Eurasian steppes. Therefore, the history of the ancient states of Mongolia is the history of the empires that dominated the Eurasian plains. Scientists and researchers have proved that many states established by nomads existed on Mongolian territory and left a deep and undeniable trace on the history of Mongolia as well as the history of the world. They have done research on the topic from different perspectives which based on the specific theories. This research is based on the qualitative method. In this article, I will examine how the ancient nomadic civilization of Mongolia connected with some Asian civilizations.
Heat convection and irreversibility of magneto-micropolar hybrid nanofluids within a porous hexagonal-shaped enclosure having heated obstacle
Authors: Ahlawat Anil , Chaudhary Shilpa , Loganathan Karuppusamy , Sharma Mukesh Kumar , Abbas Mohamed , Bhavana Munugapati 
Published: July 2024

Abstract
The significance of fluid flow under hydrothermal conditions within a hexagonal enclosure spans across numerous fields, underlining its broad applicability. However, our understanding of the free convection flow in these geometries is still limited despite its potential importance in science and technology. Therefore, this study numerically examines the heat convection and entropy generation within a porous hexagonal cavity containing a heated obstacle while subjected to a static magnetic field of intensity B
0. Micropolar hybrid nanofluid, composed of TiO2 and graphene oxide nanoparticles, was used to fill the hexagonal cavity with water as the base fluid. The finite difference method is associated with successive over-relaxation, successive relaxation, and Gauss–Seidel techniques, which are used to solve the dimensionless governing partial differential equations. The desired outcomes are computed using in-house developed MATLAB codes. A specific result from prior research findings is used to validate the accuracy of these MATLAB codes. The outcomes demonstrate that an upsurge in Ra from 104 to 106 and

ϕ

hnf

{\phi }_{{\rm{hnf}}}

from 0 to 4% leads to an enhancement in NuABW to 53.05 and 3.14%, respectively. However, NuABW diminishes by approximately 0.797 and 4.135% as Ha increases from 0 to 20 and K
0 increases from 2 to 7.5, respectively. The average Bejan number (Beavg) consistently decreases as Ra increases, but Beavg improves as Ha, vortex viscosity parameter (K
0), and

ϕ

hnf

{\phi }_{{\rm{hnf}}}

increase. The most important finding of the work is that the position of the heated obstacle significantly influences both the heat convection and entropy generation processes.
Coping with Crises: A Study of Humor Appeal in Moroccan Advertising during the COVID-19
Authors: Chirig Abdelkrim , Bouziane Karima , Zakhir Marouane 
Published: July 2024

Introduction. The emergence of COVID-19 prompted diverse advertising strategies globally, with humor appeal being one of the notable approaches. Method. Thus, the aim of this research is to examine and analyze the utilization of humor appeal in Moroccan advertising during the pandemic, employing a semiotic perspective. Analysis. The study adopts a qualitative approach and employs Barthes’ model of denotative and connotative meanings for analysis. Results. The findings indicate that when humor is employed contextually, it significantly enhances the impact of the advertisements. The study reveals the creativity and adaptability of Moroccan advertising agencies in utilizing humor appeal to engage audiences during the crisis. Conclusion. This research highlights the effectiveness of humor appeal in advertising during unprecedented times, providing insights into adaptive advertising strategies through a semiotic analysis of the Moroccan context.
How much gaming is too much? An analysis based on psychological distress
Authors: Katz Dana , Horváth Zsolt , Pontes Halley M. , Koncz Patrik , Demetrovics Zsolt , Király Orsolya 
Published: July 2024

AbstractBackgroundWhile there are calls to restrict the time spent on gaming because it is seen as problematic and potentially leading to gaming disorder (GD), there is conflicting evidence about this issue. We explored the association between the average weekly time spent gaming and reported GD symptoms. Additionally, Latent Profile Analysis was employed to investigate how time spent gaming relates to variables representing psychological distress (PD), such as satisfaction with life, symptoms of depression, and perceived stress.MethodsData were collected using surveys with a large sample of highly engaged gamers (N = 14,740; Mage = 24.14 years, SDage = 7.0, 89.3% males).ResultsWe observed a positive, close to linear association between time spent gaming and GD symptoms. Groups at risk of GD played for about 42 h (SD = 19) on average, according to the American Psychiatric Association and World Health Organization frameworks. Furthermore, we identified four profiles representing varying levels of PD. Gamers reporting very high levels of PD (4.2% of the sample) played for 33 h per week on average. Remarkably, a substantial percentage of the sample (41.9%) showed no PD despite playing for 26 h per week.ConclusionThe association between gaming time and PD is complex as even prolonged time spent gaming can be unproblematic for many gamers.