bluuebunny/crossref_metadata_2025_split huggingface dataset:
Technical aspects of clinical videoconferencing: a large scale review of the literature
Authors: Fatehi Farhad , Armfield Nigel R , Dimitrijevic Mila , Gray Leonard C 
Published: February 2015

Summary Telemedicine has been increasingly researched during the past few decades and the technology used by health care providers and recipients has changed dramatically. However, little has been published on technical characteristics of video consultations and how these characteristics have changed over time due to rapid advancement of information and communication technology. We aimed to summarize various types of technologies used for interactive videoconferencing between health care providers and patients, and identify the trend of their change from 2002 to 2012. A comprehensive electronic search was performed using PubMed, Embase and CINAHL databases which yielded 2,411 unique records. After screening at title/abstract level, full texts of 505 articles were retrieved and explored for technical information of videoconferencing. The trend of number of publications fluctuated between 41 and 47 articles with no specific pattern, though a dip in 2004 (n = 35) and drastic increase in 2012 (n = 68) was evident. The equipment used for videoconferencing was not mentioned in 15% of the papers. Dedicated VC systems (CODECs), were the most commonly used hardware, followed by computer/laptop/notebook. The connection speed (bandwidth) was not reported in 46% of the papers. The proportion of articles reporting the connection speed declined over time. Details of image quality and frame rate were mentioned in 11% and 5% of the papers, respectively. The results of this study showed that a high proportion of telemedicine papers lack sufficient technical details that limits their repeatability and generalizability.
Plant-based oral tolerance to hemophilia therapy employs a complex immune regulatory response including LAP+CD4+ T cells
Authors: Wang Xiaomei , Su Jin , Sherman Alexandra , Rogers Geoffrey L. , Liao Gongxian , Hoffman Brad E. , Leong Kam W. , Terhorst Cox , Daniell Henry , Herzog Roland W. 
Published: February 2015

Key PointsCoadministering FIX orally and systemically induces tolerance via complex immune regulation, involving tolerogenic dendritic and T-cell subsets. Induced CD4+CD25−LAP+ regulatory T cells with increased IL-10 and TGF-β expression and CD4+CD25+ regulatory T cells suppress antibody formation against FIX.
Mild cognitive impairment and deficits in instrumental activities of daily living: a systematic review
Authors: Jekel Katrin , Damian Marinella , Wattmo Carina , Hausner Lucrezia , Bullock Roger , Connelly Peter J , Dubois Bruno , Eriksdotter Maria , Ewers Michael , Graessel Elmar , Kramberger Milica G , Law Emma , Mecocci Patrizia , Molinuevo José L , Nygård Louise , Olde-Rikkert Marcel GM , Orgogozo Jean-Marc , Pasquier Florence , Peres Karine , Salmon Eric , Sikkes Sietske AM , Sobow Tomasz , Spiegel René , Tsolaki Magda , Winblad Bengt , Frölich Lutz 
Published: February 2015

Abstract
Introduction
There is a growing body of evidence that subtle deficits in instrumental activities of daily living (IADL) may be present in mild cognitive impairment (MCI). However, it is not clear if there are IADL domains that are consistently affected across patients with MCI. In this systematic review, therefore, we aimed to summarize research results regarding the performance of MCI patients in specific IADL (sub)domains compared with persons who are cognitively normal and/or patients with dementia.

Methods
The databases PsycINFO, PubMed and Web of Science were searched for relevant literature in December 2013. Publications from 1999 onward were considered for inclusion. Altogether, 497 articles were retrieved. Reference lists of selected articles were searched for potentially relevant articles. After screening the abstracts of these 497 articles, 37 articles were included in this review.

Results
In 35 studies, IADL deficits (such as problems with medication intake, telephone use, keeping appointments, finding things at home and using everyday technology) were documented in patients with MCI. Financial capacity in patients with MCI was affected in the majority of studies. Effect sizes for group differences between patients with MCI and healthy controls were predominantly moderate to large. Performance-based instruments showed slight advantages (in terms of effect sizes) in detecting group differences in IADL functioning between patients with MCI, patients with Alzheimer’s disease and healthy controls.

Conclusion
IADL requiring higher neuropsychological functioning seem to be most severely affected in patients with MCI. A reliable identification of such deficits is necessary, as patients with MCI with IADL deficits seem to have a higher risk of converting to dementia than patients with MCI without IADL deficits. The use of assessment tools specifically designed and validated for patients with MCI is therefore strongly recommended. Furthermore, the development of performance-based assessment instruments should be intensified, as they allow a valid and reliable assessment of subtle IADL deficits in MCI, even if a proxy is not available. Another important point to consider when designing new scales is the inclusion of technology-associated IADL. Novel instruments for clinical practice should be time-efficient and easy to administer.
Religion and the risk of suicide: longitudinal study of over 1 million people
Authors: O'Reilly Dermot , Rosato Michael 
Published: February 2015

BackgroundDurkheim's seminal historical study demonstrated that religious affiliation reduces suicide risk, but it is unclear whether this protective effect persists in modern, more secular societies.AimsTo examine suicide risk according to Christian religious affiliation and by inference to examine underlying mechanisms for suicide risk. If church attendance is important, risk should be lowest for Roman Catholics and highest for those with no religion; if religiosity is important, then ‘conservative’ Christians should fare best.MethodA 9-year study followed 1 106 104 people aged 16–74 years at the 2001 UK census, using Cox proportional hazards models adjusted for census-based cohort attributes.ResultsIn fully adjusted models analysing 1119 cases of suicide, Roman Catholics, Protestants and those professing no religion recorded similar risks. The risk associated with conservative Christians was lower than that for Catholics (HR = 0.71, 95% CI 0.52–0.97).ConclusionsThe relationship between religious affiliation and suicide established by Durkheim may not pertain in societies where suicide rates are highest at younger ages. Risks are similar for those with and without a religious affiliation, and Catholics (who traditionally are characterised by higher levels of church attendance) do not demonstrate lower risk of suicide. However, religious affiliation is a poor measure of religiosity, except for a small group of conservative Christians, although their lower risk of suicide may be attributable to factors such as lower risk behaviour and alcohol consumption.
Cognitive–behavioural therapy for anxiety in dementia: pilot randomised controlled trial
Authors: Spector Aimee , Charlesworth Georgina , King Michael , Lattimer Miles , Sadek Susan , Marston Louise , Rehill Amritpal , Hoe Juanita , Qazi Afifa , Knapp Martin , Orrell Martin 
Published: February 2015

BackgroundAnxiety is common and problematic in dementia, yet there is a lack of effective treatments.AimsTo develop a cognitive–behavioural therapy (CBT) manual for anxiety in dementia and determine its feasibility through a randomised controlled trial.MethodA ten-session CBT manual was developed. Participants with dementia and anxiety (and their carers) were randomly allocated to CBT plus treatment as usual (TAU) (n= 25) or TAU (n= 25). Outcome and cost measures were administered at baseline, 15 weeks and 6 months.ResultsAt 15 weeks, there was an adjusted difference in anxiety (using the Rating Anxiety in Dementia scale) of (–3.10, 95% CI −6.55 to 0.34) for CBT compared with TAU, which just fell short of statistical significance. There were significant improvements in depression at 15 weeks after adjustment (–5.37, 95% CI −9.50 to −1.25). Improvements remained significant at 6 months. CBT was cost neutral.ConclusionsCBT was feasible (in terms of recruitment, acceptability and attrition) and effective. A fully powered RCT is now required.
Biventricular arrhythmogenic cardiomyopathy: a paradigmatic case
Authors: Calcagnino M. , Girardengo G. , Ghidoni A. , Kotta M. C. , Di Blasio A. , Revera M. , Torlasco C. , Perego G. , Bilo B. , Dagradi F. , Crotti L. , Parati G. , Schwartz P. J. , Cecchi F. 
Published: February 2015

Abstract
Arrhythmogenic Cardiomyopathy is a complex clinical entity, sometimes difficult to diagnose. Three main different patterns of disease expression characterize clinically this hereditary heart muscle disease: the “classic” right ventricular form (ARVC), the “left dominant” subtype (LDAC), with primary left ventricular involvement, and the “biventricular” variant, defined by parallel involvement of both ventricles.
We report on a case of a 51 years old man with a strong family history of juvenile sudden cardiac death of supposed ischaemic origin and personal history of ventricular arrhythmias and supposed myocarditis. We demonstrate how an accurate anamnesis plus correct interpretation of traditional non invasive tests followed by more sophisticate new non invasive tests such as cardiac magnetic resonance and genetic testing allowed to reach the correct diagnosis.
Islam dan Pendidikan Perempuan
Authors: Muhammad Husein 
Published: February 2015

Paper ini membahas tentang perlunya kesetaraan laki-laki dan perempuan dalam pendidikan. Melalui penelusuran teks-teks sejarah, karya-karya ulama klasik di dunia Islam sejak jaman sahabat hingga konteks Indonesia masa kini, ditemukan adanya dinamika dan variasi apresiasi masyarakat, pandangan ilmuwan terhadap kesempatan pendidikan maupun kepemimpinan perempuan dalam politik di duniaIslam. pada sebagian kurun sejarah kaum wanita dianggap sebagai warga kelas dua sehingga tidak memiliki akses terhadap pendidikan maupun pengembangan diri yang setara dengankaum laki-laki. Penulis kemudian mengelaborasi pembahasan tersebut dengan konteksnya di Indonesia. Studi ini menyimpulkan bahwa perempuan harus dimerdekakan dari situasi kekerasan atas nama apapun untuk dapat mengembangkan potensi-potensi dirinya. kebijakan-kebijakan public harus dirumuskan untuk memungkinkan perempuan menjadi ahli dalam melakukan peran-peran sosial, politik dan kebudayaannya disamping dan bersama kaum laki-laki.
Bias Gender dalam Buku Teks Pendidikan Agama Islam dan Kristen
Authors: Murfi Ali 
Published: February 2015

Penelitian ini dilakukan untuk menyingkap bias gender dalam buku teks pendidikan agama Islam dan Kristen sebagai dasar untuk mempromosikan pendidikan agama berwawasan gender secara faktual. Hasil penelitian menunjukkan bahwa buku teks pelajaran pendidikan agama Islam dan Kristen yang dipelajari oleh siswa dewasa ini, hanya berisi sedikit nilai norma gender.Oleh karena itu, perlu adanya revisi materi pendidikan agama yang lazim diimplementasikan pemahaman tentang bias gender oleh para guru profesional. Hal ini sebagai gerakan inovasi pendidikan agama tentang kesetaraan (equality) dan keadilan (equity) antara perempuan dengan lakilaki dalam akses ekonomi, sosial budaya dan politik
Bias Gender dalam Buku Bahasa Arab Siswa MA Kelas X dengan Pendekatan Saintifik 2013
Authors: Shodiq Muhammad Jafar 
Published: February 2015

Gender adalah perbedaan antara laki-laki dan perempuan dalam peran, fungsi, hak, tanggung jawab dan perilaku yang dibentuk oleh tata nilai sosial budaya, dan adat istiadat. Bias gender adalah keadaan yang menunjukkan sikap berpihak lebih pada laki-laki daripada perempuan. Artikel ini dimaksudkan untuk menjelaskan bias gender dalam buku bahasa Arab siswa kelas X yang ditulis berdasarkan pendekatan saintifik sebagai ciri khas kurikulum 2013. Buku siswa yang digunakan sebagai bahan ajar pokok oleh para guru mereka, sunggu penting dalam menunjang proses pembelajaran. Hasil analisis data penelitian tersebut menunjukkan bahwa masih terjadi bias gender dalam buku tersebut dalam bentuk gambar dan teks.
Relasi Gender dan Pendidikan Islam
Authors: Rohmah Nur , Ulinnuha Labib 
Published: February 2015

Konsep kesetaraan laki-laki dan perempuan ataupun konsep feminisme yang ditawarkan oleh Barat, belum dapat diterima oleh sebagian besar masyarakat Islam. Hal ini dikarenakan oleh legitimasi dari dogma agama, yang timpang dan cenderung berpihak kepada laki-laki, yang dianut sebagian besar orang Islam, yang masih terus berlangsung hingga sekarang ini. Konsep kesetaraan antara laki-laki dan perempuan yang diharapkan oleh Islam dapat diperoleh dengan jalan menelaah lebih jauh pada pedoman ajaran Islam (Al-Qur’an dan Al-Hadits). Konsep kesetaraan yang dikehendaki masyarakat Islam diilhami dari segi persamaan penciptaannya, fungsi dan kedudukan di dunia dan kebebasan bertauhid serta beribadah ke pada Allah antara laki-laki dan perempuan.
Transcription factor‐mediated reprogramming toward hematopoietic stem cells
Authors: Ebina Wataru , Rossi Derrick J 
Published: February 2015

AbstractDe novo generation of human hematopoietic stem cells (HSCs) from renewable cell types has been a long sought‐after but elusive goal in regenerative medicine. Paralleling efforts to guide pluripotent stem cell differentiation by manipulating developmental cues, substantial progress has been made recently toward HSC generation via combinatorial transcription factor (TF)‐mediated fate conversion, a paradigm established by Yamanaka's induction of pluripotency in somatic cells by mere four TFs. This review will integrate the recently reported strategies to directly convert a variety of starting cell types toward HSCs in the context of hematopoietic transcriptional regulation and discuss how these findings could be further developed toward the ultimate generation of therapeutic human HSCs.
Xanthogranulomatous hypophysitis: a rare and often mistaken pituitary lesion
Authors: Gopal-Kothandapani Jaya Sujatha , Bagga Veejay , Wharton Stephen B , Connolly Daniel J , Sinha Saurabh , Dimitri Paul J 
Published: February 2015

Summary
Xanthogranulomatous hypophysitis (XGH) is a very rare form of pituitary hypophysitis that may present both clinically and radiologically as a neoplastic lesion. It may either be primary with an autoimmune aetiology and can occur in isolation or as a part of autoimmune systemic disease or secondary as a reactive degenerative response to an epithelial lesion (e.g. craniopharyngioma (CP), Rathke's cleft cyst, germinoma and pituitary adenomas) or as a part of a multiorgan systemic involvement such as tuberculosis, sarcoidosis or granulomatosis. It may also present with a variation of symptoms in children and adults. Our case series compares the paediatric and adult presentations of XGH and the differential diagnoses considered in one child and two adult patients, highlighting the wide spectrum of this condition. Endocrine investigations suggested panhypopituitarism in all three patients and imaging revealed a suprasellar mass compressing the optic chiasm suggestive of CP or Rathke's cleft cyst in one patient and non-functioning pituitary macroadenoma in two patients. Magnetic resonance imaging (MRI) demonstrated mixed signal intensities on T1- and T2-weighted sequences. Following endoscopic transsphenoidal surgery, histological analysis revealed necrotic material with a xanthogranulomatous reaction confirming XGH in two patients and a necrobiotic granulomatous chronic inflammatory infiltrate with neutrophils in one patient, which is not typical of current descriptions of this disorder. This case series describes the wide spectrum of XGH disease that is yet to be defined. Mixed signal intensities on T1- and T2-weighted MRI sequences may indicate XGH and diagnosis is confirmed by histology. Histological variation may indicate an underlying systemic process.

Learning points

XGH is a rare form of pituitary hypophysitis with a wide clinical and histological spectrum and can mimic a neoplastic lesion.

XGH primarily presents with growth arrest in children and pubertal arrest in adolescents. In adults, the presentation may vary.

A combination of hypopituitarism and mixed signal intensity lesion on MRI is suggestive of XGH and should be considered in the differential diagnosis of sellar lesions.

Radical surgery is the treatment of choice and carries an excellent prognosis with no recurrence.
The impact of metabolic risk management on recurrence of urinary stones
Authors: Akin Yigit , Yucel Selcuk , Danisman Ahmet , Erdogru Tibet , Baykara Mehmet 
Published: February 2015

Introduction: Urinary stone disease is a common urologic problem and recurrence in stone formation is a very familiar issue to urologists. Although recurrence in stone formation has been linked to metabolic abnormalities, it can be accessible by metabolic risk analysis studies.Methods: Herein, we present our experience in metabolic risk management on recurrence of urinary stones for 10 years in Akdeniz University School of Medicine department of Urology. We retrospectively analyzed Akdeniz University Urinary Stone Database between dates of January 2000 and December 2010. We found over 3500 patients who were managed by SWL (shock wave lithotripsy) or PCNL (percutaneus nephrolithotripsy) or URS (Ureterorenoscopic lithotripsy) or open surgery.Results: 525 patients’ metabolic risk analysis was ordered due to recurrent urinary stone disease. Only 134 (25.5 %) current metabolic analysis were returned. Mean patient age was 32.2 years (range: 19-82 years).Patients were 103 male and 31 female. Stone analysis results were CaOx monohydrate in 48 (35.8 %), CaOx dihydrate in 8 (5.9 %), CaOx mono and dihydrate in 70 (52.2 %), uric acid in 3, CaOx monohydrate and uricacid in 2, cystine in 2, and struvite in 1 patient, respectively. The metabolic risk analysis showed some abnormality in 54 (40.2 %) patients.Conclusion: Although compliance to metabolic risk analysis studies is low among recurrent urinary stone formers, some significant metabolic abnormalities could be detected in those who are effectively screened.Recurrence of urinary stones in patients who are started on appropriate metabolic management can be prevented.
Adherence to oral anticoagulation therapy
Authors: Lekic Lana , Lekic Alen , Begić Alden 
Published: February 2015

Introduction: Warfarin is the most frequently prescribed anticoagulant. Clinical treatment is demanding because of the narrow therapeutic range and considerable differences between the patients. The aim of this survey is to establish adherence to warfarin in subjects who have been prescribed warfarin as a long-term therapy.Methods: The survey included 30 subjects, and was conducted at local pharmacy store. Statistical processing was carried out using the SPSS (ver. 21.) software. Used for qualitative variables was the Chi-square test, and for quantitative ones the ANOVA test. Data were provided in the form of tables and charts. Level of significance was p=0.05.Results: The survey included 30 subjects, 14 men and 16 women. Of the total number of polled subjects, 15 were informed by a health care professional about the specificities of warfarin use, 7 said they were not informed, while 8 said they did not know. Most compliant in terms of regularly taking their medicines were pensioners, followed by the unemployed, χ2=13.231; p<0.05. The number of subjects within the expected therapeutic INR range was 22 (p<0.05).Conclusion: Strict compliance with the warfarin regimen is important in order to increase its effectiveness, extend the time and strengthen the intensity of anticoagulant action in the body. That is why the target groups of patients, who use warfarin, need additional information before and during therapy, in order to avoid side effects, and at the same time maintain therapeutic efficacy of the medicine throughout the treatment.
A Network for Eating and Nutrition as a platform for cooperation over the organisational borders between healthcare sectors in Sweden
Authors: Pajalic Zada , Westergren Albert 
Published: February 2015

Introduction: Requirements to implement scientific knowledge in practice within the Swedish health and social care sectors have increased during the last decades. One of these networks was the Network for Eating and Nutrition that began in 2003. The aim of this study was to retrospectively evaluate how the Network for Eating and Nutrition has functioned during a period of ten years and in what way it has affected work practice.Methods: This is a descriptive qualitative study. Data sources for this study were meeting records collected over 10 years and two evaluation surveys (at five and 10 years). Participants were members of the Network for Eating and Nutrition (n=12 at five years and n=10 at 10 years). The manifest qualitative content analysis was used.Results: The Network for Eating and Nutrition was seen as offering support for personal and organisational knowledge development. Further aspects of support from the workplaces of the members and the significance for the work places were described. Further the Network for Eating and Nutrition reached out to care receivers by using specifically tailored education programmes and material. The Network for Eating and Nutrition results and recommendations were described as important references for the development of nutrition routines.Conclusion: Networks between organisations with different professional backgrounds can form a basis for knowledge exchange both for focus on the specific topic but also on how to work with quality improvement, i.e. evidence based practice.
Binning Method for Mapping Irregularly Distributed Continuous Resistivity Profiling Data onto a Regular Grid for 3-D Inversion
Authors: Xu Tian , Dunbar John A 
Published: February 2015

Continuous resistivity profiling (CRP) is an emerging direct current (DC) resistivity method that is increasingly used in shallow fresh water and marine environments to support hydrogeological and near-surface geophysical studies. CRP is popular because it allows efficient data acquisition. However, it is generally not possible to precisely control the spacing and orientation of profiles during CRP data acquisition, resulting in irregularly distributed data. For 2-D profiles, the irregular distribution is handled by extracting relatively straight segments for inversion and using either interpolation or irregular element widths in the inversion process to account for unevenly spaced data along the profiles. Three-dimensional (3-D) inversion of CRP data sets is more challenging because most commercial inversion codes are applicable only to parallel or sub-parallel survey lines, requiring data on a regular grid. In this paper, we develop a technique for binning irregularly distributed CRP data onto a regular grid, suitable for most 3-D inversion codes. We evaluate the method on synthetic data sets, as well as field CRP data sets collected from two water reservoirs on Maui Island, Hawaii. Numerical results of the synthetic data inversion show that 20% and 10% model misfit between a “control group” and binned data can be achieved with data densities of 5 and 15 measurements in each bin, respectively. Also, the 3-D inverted resistivity volumes of the binned field CRP data sets show good agreement with independently collected 2-D profiles, resolving the same subsurface features.