bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cardiac Monitoring During Adjuvant Trastuzumab-Based Chemotherapy Among Older Patients With Breast Cancer
Authors: Chavez-MacGregor Mariana , Niu Jiangong , Zhang Ning , Elting Linda S. , Smith Benjamin D. , Banchs Jose , Hortobagyi Gabriel N. , Giordano Sharon H. 
Published: May 2015

Purpose Patients treated with adjuvant trastuzumab require adequate cardiac monitoring. We describe the patterns of cardiac monitoring and evaluate factors associated with adequate monitoring in a large population-based study of older patients with breast cancer. Patients and Methods Patients age 66 years or older with full Medicare coverage, diagnosed with stage I to III breast cancer between 2005 and 2009, and treated with adjuvant trastuzumab-based chemotherapy were identified in the SEER-Medicare and the Texas Cancer Registry-Medicare databases. The adequacy of cardiac monitoring was determined. Chemotherapy, trastuzumab use, cardiac monitoring, and comorbidities were identified by using International Classification of Diseases, 9th revision and Healthcare Common Procedure Coding System codes. Prescribing physician characteristics were also evaluated. Analyses included descriptive statistics and multilevel logistic regression models. Results In all, 2,203 patients were identified; median age was 72 years. Adequate monitoring was identified in only 36.0% of the patients (n = 793). In the multivariable model, factors associated with optimal cardiac monitoring included a more recent year of diagnosis (hazard ratio [HR], 1.83; 95% CI, 1.32 to 2.54), anthracycline use (HR, 1.39; 95% CI, 1.14 to 1.71), female prescribing physician (HR, 1.37; 95% CI, 1.10 to 1.70), and physician graduating after 1990 (HR, 1.66; 95% CI, 1.29 to 2.12). The presence of cardiac comorbidities was not a determinant for cardiac monitoring. Of the variance in the adequacy of cardiac monitoring, 15.3% was attributable to physician factors and 5.2% to measured patient factors. Conclusion A large proportion of patients had suboptimal cardiac monitoring. Physician characteristics had more influence than measured patient-level factors in the adequacy of cardiac monitoring. Because trastuzumab-related cardiotoxicity is reversible, efforts to improve the adequacy of cardiac monitoring are needed, particularly in vulnerable populations.
The influence of motion quality on responses towards video playback stimuli
Authors: Ware Emma , Saunders Daniel R. , Troje Nikolaus F. 
Published: May 2015

ABSTRACTVisual motion, a critical cue in communication, can be manipulated and studied using video playback methods. A primary concern for the video playback researcher is the degree to which objects presented on video appear natural to the non-human subject. Here we argue that the quality of motion cues on video, as determined by the video's image presentation rate (IPR), are of particular importance in determining a subject's social response behaviour. We present an experiment testing the effect of variations in IPR on pigeon (Columbia livia) response behaviour towards video images of courting opposite sex partners. Male and female pigeons were presented with three video playback stimuli, each containing a different social partner. Each stimulus was then modified to appear at one of three IPRs: 15, 30 or 60 progressive (p) frames per second. The results showed that courtship behaviour became significantly longer in duration as IPR increased. This finding implies that the IPR significantly affects the perceived quality of motion cues impacting social behaviour. In males we found that the duration of courtship also depended on the social partner viewed and that this effect interacted with the effects of IPR on behaviour. Specifically, the effect of social partner reached statistical significance only when the stimuli were displayed at 60 p, demonstrating the potential for erroneous results when insufficient IPRs are used. In addition to demonstrating the importance of IPR in video playback experiments, these findings help to highlight and describe the role of visual motion processing in communication behaviour.
The juxtamembrane region of synaptotagmin 1 interacts with dynamin 1 and regulates vesicle fission during compensatory endocytosis in endocrine cells
Authors: McAdam Robyn L. , Varga Kelly T. , Jiang Zhongjiao , Young Fiona B. , Blandford Vanessa , McPherson Peter S. , Gong Liang-Wei , Sossin Wayne S. 
Published: May 2015

ABSTRACT
Synaptotagmin 1 (Syt1) is a synaptic vesicle protein that is important for the kinetics of both exocytosis and endocytosis, and is thus a candidate molecule to link these two processes. Although the tandem Ca2+-binding C2 domains of Syt1 have important roles in exocytosis and endocytosis, the function of the conserved juxtamembrane (jxm) linker region has yet to be determined. We now demonstrate that the jxm region of Syt1 interacts directly with the pleckstrin homology (PH) domain of the endocytic protein dynamin 1. By using cell-attached capacitance recordings with millisecond time resolution to monitor clathrin-mediated endocytosis of single vesicles in neuroendocrine chromaffin cells, we find that loss of this interaction prolongs the lifetime of the fission pore leading to defects in the dynamics of vesicle fission. These results indicate a previously undescribed interaction between two major regulatory proteins in the secretory vesicle cycle and that this interaction regulates endocytosis.
Catalytic Property of SAPO-18/SAPO-34 Intergrown Molecular Sieve in 1-Butene Cracking
Authors: Hu Yunfeng , Chen Huan , Hu Ying , Deng Jun , Lv Zhongyuan , Zhang Hongsheng 
Published: May 2015

Abstract
SAPO-18 (AEI)/SAPO-34 (CHA) intergrown molecular sieve (AC-HS) was prepared by hydrothermal synthesis. As evidenced by XRD, SEM, BET, and NH3-TPD analyses, AC-HS had unconventional physical and chemical properties such as crystal structure, crystal morphology, surface area, and acidity. Compared with SAPO-18 and SAPO-34 mechanical mixture (AC-MM), AC-HS showed better initial activity and higher selectivities of C3H6 and C2H4 + C3H6 in 1-butene cracking under the reaction conditions. The selectivities of C3H6 and C2H4 + C3H6 reached approximately 61.09% and 90.28%, respectively, when conversion was &gt;70%. Regarding the SAPO-18/SAPO-34 intergrown molecular sieve, the relationship of acidity and catalytic performance was not close in 1-butene cracking, and the intergrowth structure should play a significant important role in the selectivity of olefins.
Preferential Removal of Perchlorate Ion from Water Using Self-assembled Constructions of Cationic 3D Coordination Frameworks with Methylene Units
Authors: Murakami Aya , Yamanishi Katsunori , Sone Eriko , Kondo Mitsuru 
Published: May 2015

Abstract
Four new Co(II)-coordination polymers have been prepared from treatments of a CoII source with bis[2-(1H-imidazol-1-yl)ethyl]ether (bie) or 1,5-bis(1H-imidazol-1-yl)pentane (bipen), which are bis-imidazole-type ligands with hydrophobic polymethylene units. Structural characterizations have shown that their compounds create hydrophobic cavities for anions in their cationic 3D coordination frameworks. The self-assembled construction of the frameworks in aqueous solutions containing various inorganic anions trapped perchlorate ion selectively in the cavities. Because the product is insoluble in water, perchlorate ion was selectively removed from the aqueous solutions.
Charge Distributions of Gas-phase SN2 Reactions: ABEEM-σπ Method Compared with Potential Acting on an Electron in a Molecule
Authors: Ding Yanli , Han Xiaojing , Sun Changliang , Mu Jirong 
Published: May 2015

Abstract
The SN2 reactions at C and Si have been investigated by ABEEM-σπ method compared with the potential acting on an electron in a molecule (PAEM). The ABEEM-σπ model demonstrates the charge distributions of the atom region, bond region, and lone-pair electron region during the course of the reaction. The differences between title reactions have been demonstrated. Studies indicate that there are good linear correlations among the charges obtained by ABEEM-σπ method, the force constants, the relative energies, the ionization potentials, etc. This study enhances our understanding of the electron transfer from the nucleophile to the leaving group.
Industrial Policy and the Management of Technological Development of the Industrial Complex of Russia in Conditions of Forced Autarchy
Authors: Быстров  , Bystrov Andrey , Свирчевский  , Svirchevskiy Vadim , Юсим  , Yusim Vyacheslav 
Published: May 2015

As the history shows, those states are to survive, which within periods of
crises and external threats are able to put aside outworn stereotypes of their
previous existence. In the XXI century new challenges have put Russia to the
task of accelerating its technological and economic development; otherwise
Russia is to give up its status of a world’s great power. As it is quite clear
now, the efficient economy — is the economy based on intense use of new
knowledge. It is also clear enough, that the package of decisions, aimed to
provide transition to the efficient economy can be worked out on the basis
of ingenuous and unconventional decisions, especially since the prevailing
conditions of a present day seem to be extremely unfavorable.
Company Employees’ Labor Motivation As an Ongoing Cyclic Process: Analysis of Theories and How to Apply These in Practice
Authors: Альхименко  , Alkhimenko O. 
Published: May 2015

The category of labor motivation is analyzed along with its features. It is also
considered, how this category relates to such economic terms, as “incentives”,
“motive”, “needs”, “interest”. The author’s interpretation of how to motivate
personnel together with detailed stage by stage description of the process
are given. Further, the arguments, proving that the labor motivation should
be classified as the ongoing cyclic process of labor activities are presented.
Considerable attention is given to theories of labor motivation, developed
both by national and foreign economists, and how these theories can be
applied in practice within this country’s realities. Conclusions made by the
author can be useful in practical work of present-day companies’ managers.
Revisiting the Issue of Economic Growth and Development...
Authors: Каленов  , Kalenov Oleg 
Published: May 2015

The paper considers several theories concerning economic growth and
development, and makes an attempt to classify these theories, based on
growth and development driving forces. The author suggests arguments to
prove his proprietary approach to defining the concepts of “economic growth”
and “ economic development” and highlights specifics of the said concepts.
An exploratory study of child commercial sexual exploitation in the hospitality industry in the United States
Authors: Kalargyrou Valentini , Woods Robert 
Published: May 2015

Abstract
This study examines the phenomena of child sex trafficking and commercial sexual exploitation as well as how the hospitality industry can be proactive in fighting for human rights in the context of corporate social responsibility (CSR). Seven hospitality companies have signed End Child Prostitution and Trafficking (ECPAT)-USA’s Code of Conduct for the Protection of Children from Sexual Exploitation in Travel and Tourism, also referred to as The Code. The initiative of seven hospitality companies and the purpose of The Code is to provide awareness and tools to fight against the sexual exploitation of children in the hospitality and tourism contexts. Whether and how to become involved with this movement tests hospitality companies’ approach to strategic CSR. These companies can gain a competitive advantage by creating a safe and socially sustainable environment for their guests, employees and their community, as well as a good reputation by investing in strategic and long-term positive social responsibility activities related to combating child sex trafficking and commercial sexual exploitation.
A reconceptualization of gastronomy as relational and reflexive
Authors: Kesimoğlu Ayşegül 
Published: May 2015

Abstract
This article focuses on the increasing fashionableness of gastronomic forms: their ‘symbolic enhancement’, and the ensuing incorporation of their forms into tourism, policy, destination management and marketing. The symbolic (although also material) enhancement of gastronomy may also lead to its objectification rather than acknowledging that gastronomy is an abstraction, and something that is negotiated constantly amongst the members of a society. Unfortunately, the inadvertent consequence of some studies focusing on the promotion and management of gastronomy, with respect to tourism and destination management, has been the formalization of such a normative approach with a tendency to link gastronomy with the wider debates on heritage. This article proposes a different way of looking at gastronomy: one in which gastronomy is relational, reflexive and negotiable – not fixed. This is a multi-disciplinary approach that draws on sociological and cultural studies of ­tourism, gastronomy, identity, reflexivity and consumption.
The uncracked pieces in database cracking
Authors: Schuhknecht Felix Martin , Jindal Alekh , Dittrich Jens 
Published: May 2015

Database cracking has been an area of active research in recent years. The core idea of database cracking is to create indexes adaptively and incrementally as a side-product of query processing. Several works have proposed different cracking techniques for different aspects including updates, tuple-reconstruction, convergence, concurrency-control, and robustness. However, there is a lack of any comparative study of these different methods by an independent group. In this paper, we conduct an experimental study on database cracking. Our goal is to critically review several aspects, identify the potential, and propose promising directions in database cracking. With this study, we hope to expand the scope of database cracking and possibly leverage cracking in database engines other than MonetDB.
We repeat several prior database cracking works including the core cracking algorithms as well as three other works on convergence (hybrid cracking), tuple-reconstruction (sideways cracking), and robustness (stochastic cracking) respectively. We evaluate these works and show possible directions to do even better. We further test cracking under a variety of experimental settings, including high selectivity queries, low selectivity queries, and multiple query access patterns. Finally, we compare cracking against different sorting algorithms as well as against different main-memory optimised indexes, including the recently proposed Adaptive Radix Tree (ART). Our results show that: (i) the previously proposed cracking algorithms are repeatable, (ii) there is still enough room to significantly improve the previously proposed cracking algorithms, (iii) cracking depends heavily on query selectivity, (iv) cracking needs to catch up with modern indexing trends, and (v) different indexing algorithms have different indexing signatures.
M4
Authors: Jugel Uwe , Jerzak Zbigniew , Hackenbroich Gregor , Markl Volker 
Published: May 2015

Visual analysis of high-volume time series data is ubiquitous in many industries, including finance, banking, and discrete manufacturing. Contemporary, RDBMS-based systems for visualization of high-volume time series data have difficulty to cope with the hard latency requirements and high ingestion rates of interactive visualizations. Existing solutions for lowering the volume of time series data disregard the semantics of visualizations and result in visualization errors.
In this work, we introduce M4, an aggregation-based time series dimensionality reduction technique that provides error-free visualizations at high data reduction rates. Focusing on line charts, as the predominant form of time series visualization, we explain in detail the drawbacks of existing data reduction techniques and how our approach outperforms state of the art, by respecting the process of line rasterization.
We describe how to incorporate aggregation-based dimensionality reduction at the query level in a visualization-driven query rewriting system. Our approach is generic and applicable to any visualization system that uses an RDBMS as data source. Using real world data sets from high tech manufacturing, stock markets, and sports analytics domains we demonstrate that our visualization-oriented data aggregation can reduce data volumes by up to two orders of magnitude, while preserving perfect visualizations.
The case for personal data-driven decision making
Authors: Duggan Jennie 
Published: May 2015

Data-driven decision making (D3M) has shown great promise in professional pursuits such as business and government. Here, policymakers collect and analyze data to make their operations more efficient and equitable. Progress in bringing the benefits of D3M to everyday life has been slow. For example, a student asks, "If I pursue an undergraduate degree at this university, what are my expected lifetime earnings?". Presently there is no principled way to search for this, because an accurate answer depends on the student and school.
Such queries are personalized, winnowing down large datasets for specific circumstances, rather than applying well-defined predicates. They predict decision outcomes by extrapolating from relevant examples. This vision paper introduces a new approach to D3M that is designed to empower the individual to make informed choices. Here, we highlight research opportunities for the data management community arising from this proposal.
Code generation for efficient query processing in managed runtimes
Authors: Nagel Fabian , Bierman Gavin , Viglas Stratis D. 
Published: May 2015

In this paper we examine opportunities arising from the convergence of two trends in data management: in-memory database systems (imdbs), which have received renewed attention following the availability of affordable, very large main memory systems; and language-integrated query, which transparently integrates database queries with programming languages (thus addressing the famous 'impedance mismatch' problem). Language-integrated query not only gives application developers a more convenient way to query external data sources like imdbs, but also to use the same querying language to query an application's in-memory collections. The latter offers further transparency to developers as the query language and all data is represented in the data model of the host programming language. However, compared to imdbs, this additional freedom comes at a higher cost for query evaluation. Our vision is to improve in-memory query processing of application objects by introducing database technologies to managed runtimes.
We focus on querying and we leverage query compilation to improve query processing on application objects. We explore different query compilation strategies and study how they improve the performance of query processing over application data. We take C# as the host programming language as it supports language-integrated query through the linq framework. Our techniques deliver significant performance improvements over the default linq implementation. Our work makes important first steps towards a future where data processing applications will commonly run on machines that can store their entire datasets in-memory, and will be written in a single programming language employing language-integrated query and imdb-inspired runtimes to provide transparent and highly efficient querying.
Adaptive query processing on RAW data
Authors: Karpathiotakis Manos , Branco Miguel , Alagiannis Ioannis , Ailamaki Anastasia 
Published: May 2015

Database systems deliver impressive performance for large classes of workloads as the result of decades of research into optimizing database engines. High performance, however, is achieved at the cost of versatility. In particular, database systems only operate efficiently over loaded data, i.e., data converted from its original raw format into the system's internal data format. At the same time, data volume continues to increase exponentially and data varies increasingly, with an escalating number of new formats. The consequence is a growing impedance mismatch between the original structures holding the data in the raw files and the structures used by query engines for efficient processing. In an ideal scenario, the query engine would seamlessly adapt itself to the data and ensure efficient query processing regardless of the input data formats, optimizing itself to each instance of a file and of a query by leveraging information available at query time. Today's systems, however, force data to adapt to the query engine during data loading.
This paper proposes adapting the query engine to the formats of raw data. It presents RAW, a prototype query engine which enables querying heterogeneous data sources transparently. RAW employs Just-In-Time access paths, which efficiently couple heterogeneous raw files to the query engine and reduce the overheads of traditional general-purpose scan operators. There are, however, inherent overheads with accessing raw data directly that cannot be eliminated, such as converting the raw values. Therefore, RAW also uses column shreds, ensuring that we pay these costs only for the subsets of raw data strictly needed by a query. We use RAW in a real-world scenario and achieve a two-order of magnitude speedup against the existing hand-written solution.
Matching titles with cross title web-search enrichment and community detection
Authors: Londhe Nikhil , Gopalakrishnan Vishrawas , Zhang Aidong , Ngo Hung Q. , Srihari Rohini 
Published: May 2015

Title matching refers roughly to the following problem. We are given two strings of text obtained from different data sources. The texts refer to some underlying physical entities and the problem is to report whether the two strings refer to the same physical entity or not. There are manifestations of this problem in a variety of domains, such as product or bibliography matching, and location or person disambiguation.
We propose a new approach to solving this problem, consisting of two main components. The first component uses Web searches to "enrich" the given pair of titles: making titles that refer to the same physical entity more similar, and those which do not, much less similar. A notion of similarity is then measured using the second component, where the tokens from the two titles are modelled as vertices of a "social" network graph. A "strength of ties" style of clustering algorithm is then applied on this to see whether they form one cohesive "community" (matching titles), or separately clustered communities (mismatching titles). Experimental results confirm the effectiveness of our approach over existing title matching methods across several input domains.
Optimal security-aware query processing
Authors: Guarnieri Marco , Basin David 
Published: May 2015

Security-Aware Query Processing is the problem of computing answers to queries in the presence of access control policies. We present general impossibility results for the existence of optimal algorithms for Security-Aware Query Processing and classify query languages for which such algorithms exist. In particular, we show that for the relational calculus there are no optimal algorithms, whereas optimal algorithms exist for some of its fragments, such as the existential fragment.
We also establish relationships between two different models of Fine-Grained Access Control, called Truman and Non-Truman models, which have been previously presented in the literature as distinct. For optimal Security-Aware Query Processing, we show that the Non-Truman model is a special case of the Truman model for boolean queries in the relational calculus, moreover the two models coincide for more powerful languages, such as the relational calculus with aggregation operators. In contrast, these two models are distinct for non-boolean queries.