bluuebunny/crossref_metadata_2025_split huggingface dataset:
Focus on Echocardiographic and Doppler Analysis of Coronary Artery Abnormal Origin from the Pulmonary Trunk with Mild Myocardial Dysfunction
Authors: Courand Pierre‐Yves , Bozio André , Ninet Jean , Henaine Roland , Veyrier Magali , Bakloul Mohamed , Boussel Loic , Filippo Sylvie Di 
Published: January 2013

BackgroundLate presentation of abnormal origin of coronary artery from the pulmonary artery (ACAPA) is uncommon compared with early presentation, which usually induces extended myocardial necrosis and severe heart failure. The late presentation is characterized by abundant development of intercoronary collaterals resulting in mild and rare symptoms, but nevertheless can cause sudden cardiac death. Our objective was to describe presentation, cardiovascular imaging methods for diagnosis and outcomes of patients with late presentation of ACAP.MethodsThe study is a retrospective review of a single‐center database to identify all patients diagnosed with ACAPA beyond the first year of life.ResultsFrom 1976 to 2011, 10 patients were identified with ACAPA at the age of 1.1–64 years: 6 with left coronary artery from the pulmonary artery (ALCAPA) and 4 with right coronary artery from the pulmonary artery (ARCAPA). Echocardiography and Doppler imaging evidenced: (1) direct signs: the abnormal coronary ostium arising from the pulmonary trunk with retrograde coronary artery flow and (2) indirect signs: abundant intercoronary septal collaterals with anterograde flow (ARCAPA) or retrograde flow (ALCAPA) and dilatation of the controlateral normally originated coronary artery. Nine patients underwent surgical implantation of the ACAPA into the ascending aorta. After 7.9 years mean follow‐up, all were asymptomatic except one who required a second surgery.ConclusionsNoninvasive cardiovascular imaging, namely transthoracic echocardiography and Doppler specific parameters, can reach diagnosis of late presentation of ACAPA. Direct aortic implantation is a reliable and effective to establish dual coronary artery circulation and prevent risks due to myocardial ischemia.
Cyberbullying in those at clinical high risk for psychosis
Authors: Magaud Emilie , Nyman Karissa , Addington Jean 
Published: January 2013

AbstractAimSeveral studies suggest an association between experiences of childhood trauma including bullying and the development of psychotic symptoms. The use of communications technology has created a new media for bullying called ‘cyberbullying’. Research has demonstrated associations between traditional bullying and cyberbullying. Negative effects of cyberbullying appear similar in nature and severity to the reported effects of traditional bullying. Our aim was to examine the prevalence and correlates of cyberbullying in those at clinical high risk (CHR) for psychosis.MethodsFifty young people at CHR for psychosis were administered the Childhood Trauma Questionnaire with added questions about cyberbullying.ResultsCyberbullying was reported in 38% of the sample. Those who experienced cyberbullying also reported experiencing previous trauma.ConclusionIt is possible that cyberbullying may be a problem for those at CHR of psychosis, and due to the vulnerable nature of these young people may have longitudinal implications.
Clinical outcomes of long‐acting risperidone in recent versus long‐term diagnosed Belgian schizophrenic patients: results from electronic Schizophrenia Treatment Adherence Registry (e‐STAR) and Trial for the Initiation and Maintenance Of REmission in Schizophrenia with risperidone (TIMORES)
Authors: Dubois Vincent , Peuskens Joseph , Geerts Paul , Detraux Johan 
Published: January 2013

AbstractAimPotential differences in psychiatric clinical outcomes and hospitalization rates before and after the initiation of long‐acting risperidone among recently and long‐term diagnosed schizophrenia patients were studied.MethodsData from two observational studies (Trial for the Initiation and Maintenance Of REmission in Schizophrenia with risperidone (TIMORES) and electronic Schizophrenia Treatment Adherence Registry (e‐STAR)) were categorized by the recency of their diagnose and compared in several post hoc analyses. Clinical Global Impression of illness Severity (CGI‐S) and Global Assessment of Functioning (GAF) scores, as well as symptoms of clinical deterioration (including hospitalization data) at baseline, 12‐month (for TIMORES and e‐STAR) and 24‐month (for e‐STAR) follow‐up were analysed. Other outcome measures included discontinuation rate, employment status and remission attainment.ResultsStatistically significantly differences between recent and long‐term diagnosed schizophrenic patients at 12‐ and 24‐month follow‐up were found for CGI‐S (between P < 0.01 and P ≤ 0.001) and GAF (P < 0.05) scores. Other differences between both schizophrenic patient groups were found for measures of clinical deterioration, employment status and full symptomatic remission rates at 1 year. Although no consistent difference was found between recent and long‐term patient groups for hospitalization parameters, the difference in length of full hospitalization days was statistically significantly different (P < 0.01) between e‐STAR ‘Early’ and ‘Late’ patient groups at both 12‐ and 24‐month endpoints: the mean change from baseline was significantly greater for e‐STAR ‘Early’ at 12 months, but greater for e‐STAR ‘Late’ at 24 months.ConclusionsThe findings of the post hoc analyses support the significance of pharmacological interventions, such as long‐acting risperidone, in addressing discontinuity issues, especially in recently diagnosed patients.
A randomized clinical trial of a nurse telephone follow‐up on paediatric tonsillectomy pain management and complications
Authors: Paquette Julie , Le May Sylvie , Lachance Fiola Jacinthe , Villeneuve Edith , Lapointe Annie , Bourgault Patricia 
Published: January 2013

AbstractAimsTo determine the effect of a nurse telephone follow‐up on paediatric post‐tonsillectomy pain intensity, complications, and use of other healthcare services.BackgroundAfter tonsillectomy, children experience moderate‐to‐severe pain for days. Parents tend to give insufficient analgesia, with resulting increases in pain and postoperative complications. In adults, nurse telephone follow‐up for ambulatory surgeries reduces postoperative pain.DesignThe study design was a randomized clinical trial.MethodsIn this trial, children aged 4–12 years undergoing elective tonsillectomy in June–October 2010 were assigned to a nurse telephone follow‐up with parents on postoperative days 1, 3, 5 and 10, or standard care with no follow‐up but data collection. Outcomes included pain intensity, analgesics administered, complications, and healthcare use.ResultsOf 45 participants, the intervention group (n = 24) received more analgesics on postoperative days 1 and 3, increased their fluid intake at days 1 and 3, but had more constipation at day 3 than the control group (n = 21). There was no significant difference regarding pain intensity or use of healthcare resources.ConclusionNurse telephone follow‐up was beneficial for some pain management and prevention of complications, although better analgesic treatments are needed. The intervention was simple, safe, and appreciated by parents.
Exploring outcomes of a nurse practitioner‐managed cardiac surgery follow‐up intervention: a randomized trial
Authors: Sawatzky Jo‐Ann V. , Christie Sandra , Singal Rohit K. 
Published: January 2013

AbstractAimsTo describe and compare the outcomes of a nurse practitioner‐managed cardiac surgery follow‐up model of care with the standard model of primary care provider follow‐up for coronary artery bypass graft surgery patients.BackgroundAdvances in healthcare have had a favourable impact on length of stay following cardiac surgery; however, the shorter length of stay has not been accompanied by enhanced support to bridge the gap between acute care and the community setting.DesignProspective (2009–2010) randomized study.MethodsElective cardiac surgery patients (N = 200) were randomly assigned to the nurse practitioner follow‐up intervention or to the standard model of follow‐up care. The main outcomes were health‐related quality of life, patient satisfaction, symptoms, and health resource use. Outcome data were elicited via telephone interviews at 2 and 6 weeks postdischarge.ResultsBaseline differences between the two groups were non‐significant; however, at 2 weeks postdischarge, the intervention group reported significantly fewer symptoms and higher physical functioning status. At 2 and 6 weeks postdischarge, the intervention group was significantly more satisfied with the amount of help, as well as the quality of the services received. Differences in healthcare resource use were not statistically significant.ConclusionThis evidence suggests that the nurse practitioner‐managed model of follow‐up care effectively bridges the gap between institutional and primary care in the cardiac surgery population.
Experimental periodontitis induced by Porphyromonas gingivalis does not alter the onset or severity of diabetes in mice
Authors: Li H. , Yang H. , Ding Y. , Aprecio R. , Zhang W. , Wang Q. , Li Y. 
Published: January 2013

Background and ObjectiveDiabetes mellitus is believed to increase the risk and severity of periodontitis. However, less evidence is available on the converse effects of periodontitis on diabetes. The objective of the study was to investigate to what degree experimental periodontitis induced by Porphyromonas gingivalis might influence the onset and severity of diabetes in different mouse models.Material and MethodsTwenty‐eight male Tallyho/JngJ mice (type 2 diabetes), 20 male streptozotocin‐induced diabetes C57BL/6J mice (type 1 diabetes) and 20 male C57BL/6J mice at 4 wks of age were evenly divided into two groups: periodontal infection and sham infection. Periodontitis was induced by Porphyromonas gingivalis W50 (P. gingivalis) oral inoculation before the development of diabetes. Sham‐infected mice received vehicle as control. P. gingivalis in the oral cavity were identified by quantitative polymerase chain reaction. Fasting glucose, body weight and food intake levels were monitored and glucose tolerance tests were performed to assess glucose homeostasis for the onset and progression of diabetes. The level of alveolar bone loss and tumor necrosis factor‐alpha were determined in week 20 when mice were killed.ResultsMice in the infection groups developed more alveolar bone loss than those in sham‐infection groups (Tallyho p = 0.021; C57‐STZ p = 0.014; C57 p = 0.035). Hyperglycemic mice exhibited significantly more bone loss compared to those normal glucose mice (Tallyho vs. C57 p = 0.029; C57‐STZ vs. C57 p = 0.024). The level of tumor necrosis factor‐alpha was consistent with that of periodontal bone loss and hyperglycemia. There was no significant effect of mouse species on the amount of bone loss at the same level of blood glucose. No statistically significant difference or trend in glucose metabolism was found between the infection and sham‐infection group.ConclusionDiabetes enhanced the risk for periodontal disease induced by P. gingivalis. However, no converse impact was found between this periodontal infection and onset and severity of diabetes in both type 1 and 2 diabetes mice.
The Resurgence of the Vacuum Erection Device (VED) for Treatment of Erectile Dysfunction
Authors: Brison Daniel , Seftel Allen , Sadeghi-Nejad Hossein 
Published: January 2013

ABSTRACT

Introduction
Vacuum erection devices (VEDs) have been approved in the United States since 1982 and offer a viable alternative to oral phosphodiesterase type 5 inhibitors (PDE5i), injections and transurethral suppositories. Studies have demonstrated efficacy in erectile dysfunction (ED) associated with a variety of conditions. More recently, this modality has been evaluated in initial phosphodiesterase inhibitor nonresponders as well as for post-prostatectomy penile rehabilitation.

Aim
This article provides a detailed overview of the history of VEDs, a review of the literature, and a concise description of their new applications in modern urological practice.

Methods
A retrospective review of publications relevant to the field of VEDs.

Main Outcome Measures
Review of the historical milestones, evolution, and modern utilization of VEDs in modern urological protocols.

Results
Studies have demonstrated efficacy in ED associated with a variety of conditions. Early penile rehabilitation after surgery for prostate cancer with the VED appears to improve erectile function and penile length. Adverse events are transient and not serious.

Conclusions
The VED has continued to show efficacy for treatment of ED due to various etiologies and should be considered an attractive second-line therapy. In select cases such post-prostatectomy penile rehabilitation, as well as in men who cannot use a PDE5i, the vacuum device should be considered first-line treatment.
A Preliminary Report on the Usage of an Intracorporal Antibiotic Cast with Synthetic High Purity CaSO4 for the Treatment of Infected Penile Implant
Authors: Swords Kelly , Martinez Daniel R. , Lockhart Jorge L. , Carrion Rafael 
Published: January 2013

ABSTRACT

Introduction
Currently, the surgical treatment of infected penile prostheses is complete removal and either immediate salvage procedure, which carries a significant infection risk, or delayed implantation. With delayed implantation the risk of infection is lower, but the patient loses penile length and width due to corporal fibrosis.

Aim
We present our experience with the use of a novel temporary synthetic high purity calcium sulfate (SHPCaSO4) component that acts as a “spacer” at the time of removal of an infected prosthesis while providing constant delivery of local antibiotic elution to the infected area.

Main Outcome Measures
Demonstrate that the use of a novel material, SHPCaSO4, can be an innovative way to bridge the gap between removal of an infected penile implant and delayed reimplantation.

Methods
Two patients (Patient A and B) presented with pain and erythema and were found to have infected malleable penile prosthesis. Both underwent removal of all infected components, and sent for tissue culture. The SHPCaSO4 was mixed with vancomycin and tobramycin, allowed to set up for 5 minutes, and then injected into the corporal space followed by closure with 2-0 Vicryl sutures. The injected SHPCaSO4 was palpable in the penile shaft both proximally and distally, as an “intracorporal casts.”

Results
Patients denied pain postoperatively. Delayed implantation occurred at 6 weeks for patient A. This went uneventful and a new three-piece inflatable implant was inserted. Patient B underwent salvage placement of right malleable implant at 15 weeks, and here significant corporal fibrosis was encountered. Patients have had no infection since their delayed implantation (mean follow-up 4 months).

Conclusions
Data in reference to SHPCaSO4 shows that this product dissolves in approximately 4–6 weeks. This may account for the difference in the ease of delayed implantation between the two patients. Further investigation is warranted.
Decline in local abundance of bottlenose dolphins (Tursiops truncatus) in the Bay of Islands, New Zealand
Authors: Tezanos‐Pinto Gabriela , Constantine Rochelle , Brooks Lyndon , Jackson Jennifer A. , Mourão Fabiana , Wells Sarah , Scott Baker C. 
Published: January 2013

AbstractRegional populations of bottlenose dolphins (Tursiops truncatus) around New Zealand are genetically isolated from each other and the species was recently classified as nationally endangered based on relatively small population sizes and reports of high calf mortality. Here, we estimate the abundance and trends in one of these regional populations, the Bay of Islands, using a photo‐identification database collected from 1997 to 1999 and from 2003 to 2006, containing a total of 3,841 records of 317 individual dolphins. Estimates of abundance obtained with the robust design fluctuated widely but showed a significant decline in the number of dolphins present in the bay over time (7.5% annual rate of decline). Temporary emigration was random and fluctuated considerably (γ = 0.18, SE = 0.07 to γ = 0.84, SE = 0.06). Apparent survival was estimated at 0.928 (CI = 0.911–0.942). Seasonal estimates (26 seasons) obtained in POPAN also showed a significant decline in abundance (5.8% annual rate of decline). Despite the decline observed in local abundance, dolphins continue to be found regularly in the Bay of Islands, suggesting that fewer dolphins use the bay on regular basis. Consequently, it seems that a change in habitat use, mortality and possibly low recruitment could underlie the apparent local decline.
A Comparison of South American and African Preferential Pathways for Extreme Cold Events
Authors: Metz Nicholas D. , Archambault Heather M. , Srock Alan F. , Galarneau Thomas J. , Bosart Lance F. 
Published: January 2013

AbstractIn the Southern Hemisphere, a relatively well-known preferential pathway along which cold air surges equatorward is situated to the east of the Andes Mountains. In this study, a second preferred pathway is identified to the east of the African Highlands, with additional minor pathways identified east of the Brazilian Highlands and Madagascar. The primary objective of this study is to compare climatological and synoptic characteristics of extreme cold events (ECEs) along the Andes and African Highlands pathways. ECEs are defined as the top 1% coldest 925-hPa temperatures within the Andes and the African Highlands pathways using the 1977–2001 subset of the 2.5° × 2.5° 40-yr European Centre for Medium-Range Weather Forecasts (ECMWF) Re-Analysis (ERA-40). ECEs within the Andes and African Highlands pathways are associated with dynamically forced anticyclogenesis and have low-level characteristics that vary substantially. Along the Andes pathway, ECEs feature 925-hPa temperatures as much as 17°C below normal, with 925-hPa southerly winds ranging from 0 to 10 m s−1 and 925–700-hPa lapse rates as low as −3°C km−1. In contrast, ECEs along the African Highlands pathway feature 925-hPa temperatures up to 10°C below normal, with 925-hPa southerly winds ranging from 5 to 15 m s−1, and 925–700-hPa lapse rates generally between 2° and 5°C km−1. Composite analyses reveal that despite stronger southerly winds, ECEs along the African Highlands pathway are typically not as cold or stable as those along the Andes pathway because cold air from Antarctica must traverse a longer distance over water to reach Africa.
Cdc25A activity is required for the metaphase II arrest in mouse oocytes
Authors: Oh Jeong Su , Susor Andrej , Schindler Karen , Schultz Richard M. , Conti Marco 
Published: January 2013

Summary
Mammalian oocytes are arrested in metaphase of second meiosis (MII) until fertilization. This arrest is enforced by the cytostatic factor (CSF), which maintains the M-phase promoting factor (MPF) in a highly active state. Although the continuous synthesis and degradation of cyclin B to maintain the CSF-mediated MII arrest is well established, it is unknown whether cyclin-dependent kinase 1 (Cdk1) phosphorylations are involved in this arrest in mouse oocytes. Here, we show that a dynamic equilibrium of Cdk1 phosphorylation is required to maintain MII arrest. When the Cdc25A phosphatase is downregulated, mouse oocytes are released from MII arrest and MPF becomes inactivated. This inactivation occurs in the absence of cyclin B degradation and is dependent on Wee1B-mediated phosphorylation of Cdk1. Thus, our data demonstrate that Cdk1 activity is maintained during MII arrest not only by cyclin turnover but also by steady state phosphorylation.
Enfermement des mineurs délinquants. Dans les murs
Authors: Dayan Jacques 
Published: January 2013

Résumé L’enfermement des mineurs est la plus sévère des figures de la peine, et pour les mineurs la plus péjorative en termes de santé mentale, de développement et de réitération. Les aménagements entrepris dans les Établissements pénitentiaires pour mineurs peuvent-ils réduire les effets d’affiliation et de stigmatisation d’une incarcération ? Les Centres éducatifs fermés tels qu’ils sont construits offrent-ils des perspectives favorables à une entreprise pédagogique ? Celle-ci est-elle concevable sans la prise en compte de la dimension psychique de l’acte antisocial ? Nous examinons ces questions dans ce texte dans les suites de l’examen des étiologies supposées de la délinquance.
Le flux des mineurs délinquants et ses traductions éducatives. Délinquances et justice
Authors: Choquet Luc-Henry 
Published: January 2013

Résumé L’examen du flux des mineurs délinquants fait apparaître les grandes tendances résultant de l’activité des différents services concourant à une réponse pénale en augmentation. Mais les résultats de cet examen illustrent surtout la diversification des types de délinquance et des trajectoires procédurales et institutionnelles. Le cas le plus fréquent est celui de mineurs délinquants qui, ayant eu affaire avec l’institution judiciaire une première fois, ne réitèrent pas. A contrario , les mineurs qui ont commis les actes les plus graves ou qui sont fortement « réitérants » sont plus rares. Tous appellent à des prises en charge spécifiques conduites en fonction des caractéristiques des mineurs concernés et de la dynamique psychologique qui sous tend les actes et leurs circonstances.
Comprendre la délinquance ?
Authors: Dayan Jacques 
Published: January 2013

Résumé Délits et crimes sont selon É. Durkheim des acceptions issues de la conscience commune. Mais comment se forge et se transmet cette conscience ? Qu’est-ce que l’acte délictueux ? Tout acte antisocial relève-t-il d’une pathologie ? Existe-t-il une épistémologie commune aux champs sociologique et psychologique ? Nous tentons de répondre à ces questions et à leurs implications dans le champ de la justice des mineurs et des soins aux délinquants.
La vi(ll)e en rose ?
Authors: Giraud Colin 
Published: January 2013

Résumé Malgré l’apparition de « quartiers gays » au centre des métropoles occidentales depuis quelques décennies, on connaît mal les rapports des populations homosexuelles à ces espaces. Cet article interroge cette nouvelle figure de la centralité urbaine sous l’angle des trajectoires, des modes de vie et des manières d’être homosexuel des populations résidentes de deux quartiers gays de Paris et Montréal. La reconstitution de leurs trajectoires socio-spatiales, l’analyse de leurs pratiques et de leurs représentations permettent d’identifier plusieurs manières d’entrer et de vivre dans ces quartiers : le quartier gay reste investi de manière très différenciée selon les parcours et les propriétés sociales des individus. Ce résultat amène à remettre en cause certaines images uniformisantes et stigmatisantes au sujet des quartiers gays et des homosexualités contemporaines.