bluuebunny/crossref_metadata_2025_split huggingface dataset:
Digital platforms and the SDGs: A socio‐eco‐technical framework for SMEs based on cross‐case analysis
Authors: Isensee Carmen , Teuteberg Frank , Griese Kai‐Michael 
Published: August 2024

AbstractManaging the complex relationship between digitalization and sustainable development is a key challenge for many small and medium sized enterprises (SMEs). To understand strategies of forerunners in the field of digital platforms and platformization, this study performs a cross‐case analysis of three sustainability‐oriented SMEs employing multi‐sided platforms operating in three sectors (wholesale, information and communication technology, and construction) in Germany. The integrated analysis framework draws from Belief‐Action‐Outcome theory, multi‐sided platform strategies, and the sustainable development goals (SDG). The findings identify four platformization strategies and exemplarily specify contributions to SDG 2, 7, 8, 9, 12, 13, and 17. The proposed socio‐eco‐technical framework emphasizes linkages between an employed platformization strategy (technical system), the corporate culture (social system), the platform stakeholders and the SDGs (ecological system). A seven‐step approach is proposed to motivate and facilitate the development and continuous improvement of platformization for sustainability in SMEs.
Photocatalytic Synergy Between α‐Bi2O3 Nanosphere and Spindle MIL‐88A for Gas‐Phase CO2 Reduction
Authors: Ojha Niwesh , Kishore Pant Kamal 
Published: August 2024

AbstractVisible light‐active photocatalysts play a crucial role in gas‐phase photocatalytic CO2 reduction, offering significant potential for sustainable energy conversion. Herein, we present the synthesis of spindle‐shaped Iron (Fe)‐based metal‐organic framework (MOF) MIL‐88 A, coupled with distinct α‐Bi2O3 nanospheres. The α‐Bi2O3/MIL88A heterostructure is formed by interacting opposite surface charges, enhancing visible‐light absorption and efficient interfacial charge‐carrier separation. Such low‐cost photocatalysts have a 1.75 eV band gap and demonstrate enhanced efficacy in converting CO2 to CO, CH4, and H2 in water without using any sacrificial agents or noble metals compared to pristine MIL88A. In addition, in‐situ Electron Spin Resonance (ESR) analyses revealed that these unique catalysts combination promoted enhanced interfacial charge dynamics, creating efficient trapping sites for photogenerated carriers. Further, in‐situ Diffuse Reflectance Infrared Fourier Transfer Spectroscopy (DRIFTS) investigation elucidates the plausible reaction mechanism and provides an effective methodology for catalyst screening for CO2 photoreduction. This study offers an effective approach for synthesizing the earth‐abundant heterostructure from metal oxide and low‐cost MOFs, enhancing photocatalytic activity for sustainable carbon dioxide conversion into invaluable chemicals.
Azolium‐Porphyrin Electrosynthesis
Authors: Akhssas Fatima , Lin Rongning , Trojan Michal , Poyac Ludivine , Amiri Nesrine , Ertel Thibault , Fournier Sophie , Lerayer Emmanuel , Cattey Hélène , Clément Sébastien , Richeter Sébastien , Devillers Charles H. 
Published: August 2024

AbstractElectrochemical oxidation of Zn(II) 2,7,12,17‐tetra‐tert‐butylporphyrin in the presence of a series of azole derivatives (1‐methylimidazole, 1‐vinyl‐1H‐imidazole, 2‐(1H‐imidazol‐1‐yl)pyridine, 1‐methylbenzimidazole, 1‐methyl‐1H‐1,2,4‐triazole, and benzothiazole) affords the corresponding meso‐substituted azolium‐porphyrins in very mild conditions and good yields. It was found that these nucleophiles were strongly ligated to the zinc(II) azolium‐porphyrin complexes. Thus a demetalation/remetalation procedure was performed to recover the non‐azole‐coordinated zinc(II) complexes. X‐ray crystallographic structures of three azolium‐porphyrins were solved. Cyclic voltammetry analyses provided insight into the electron‐withdrawing effect of the azolium substituents.
Mathematical modeling and stress‐aware stability analysis of a nonideal multiport Single Inductor DC–DC converter for renewable energy
Authors: Gupta Ashutosh , Joshi Dheeraj 
Published: August 2024

AbstractThis paper proposes a novel configuration for a multiport boost converter (MPBC) with a single inductor (SI), accounting for equivalent series resistances (ESRs) and minimizing input switching stress. The MPBC performance is evaluated and compared with other established topologies. The proposed MPBC interfaces two unidirectional input DC power ports and a rechargeable port for an energy storage element (ESE) with two output ports. The design integrates two renewable sources with the ESE as a third source. One output is for higher voltage, linked to a single‐phase inverter for AC loads. The other output is for lower DC voltage, used for DC loads. The configuration can be adjusted based on requirements. This converter has numerous applications in renewable energy systems, electric vehicles, and agriculture. The steady‐state and small signal modeling of MPBC has been done to derive the mathematical expressions for analyzing stability, stresses (both voltage and current), and performance considering ESRs. A 240 W, MPBC is fabricated along with improved switching strategies using DSP TMS320F28379D. Experimental and simulation results are compared to show the effectiveness of proposed scheme on stability, stresses, and efficient power transfer. Output power is regulated effectively by sharing the input power thereby reducing voltage stress on switches.
Potential mechanisms of cancer stem‐like progenitor T‐cell bio‐behaviours
Authors: Ni Ling 
Published: August 2024

AbstractIn situations involving continuous exposure to antigens, such as chronic infections or cancer, antigen‐specific CD8+ T cells can become dysfunctional or exhausted. This change is marked by increased expression levels of inhibitory receptors (PD‐1 and Tim‐3). Stem‐like progenitor exhausted (Tpex) cells, a subset of exhausted cells that express TCF‐1 and are mainly found in the lymph nodes, demonstrate the ability to self‐renew and exhibit a high rate of proliferation. Tpex cells can further differentiate into transitional intermediate exhausted (Tex‐int) cells and terminally exhausted (Tex‐term) cells. Alternatively, they can directly differentiate into Tex‐term cells. Tpex cells are the predominant subset that respond to immune checkpoint inhibitors (ICI), making them a prime candidate for improving the efficacy of ICI therapy. This review article aimed to present the latest developments in the field of Tpex formation, expansion, and differentiation in the context of cancer, as well as their responses to ICIs in cancer immunotherapy. Consequently, it may be possible to develop novel treatments that exclusively target Tpex cells, thus improving overall treatment outcomes.Key points
Tpex cells are located in lymph nodes and TLS.
Several pathways control the differentiation trajectories of Tpex cells, including epigenetic factors, transcription factors, cytokines, age, sex, etc.
Structure and melting of strongly coupled dusty plasma
Authors: Issaad Mohamed 
Published: August 2024

AbstractThe structure and phase transition of a two‐dimensional dusty plasma, confined by an anisotropic power‐law potential and interacting via a screened Coulomb potential, were investigated using Monte Carlo simulations. The study varied the number of particles (), screening strength (), eccentricity parameter (), and confinement power parameter () to characterize the system's structural properties. According to the simulation results, the melting temperature is influenced by the eccentricity parameter. Reducing the eccentricity results in a corresponding decrease in the melting temperature. However, the confinement power parameter does not appear to have any impact on the melting temperature.
Clinical characteristics and outcomes of patients aged 80 years and over with heart failure: Need for better treatment
Authors: Yang Mingming , Kondo Toru , Anand Inder S. , de Boer Rudolf A. , Campbell Ross T. , Køber Lars , Lam Carolyn S.P. , Maggioni Aldo P. , Martinez Felipe A. , O'Meara Eileen , Packer Milton , Sabatine Marc S. , Kerr Saraiva Jose F. , Shah Sanjiv J. , Zannad Faiez , Zile Michael R. , Jhund Pardeep S. , Solomon Scott D. , McMurray John J.V. 
Published: August 2024

AimsAlthough the prevalence of heart failure (HF) increases markedly with advancing age, surprisingly little is known about HF in the very elderly. The aim of this study was to describe the clinical characteristics and outcomes of octogenarians with HF.Methods and resultsIndividual participant meta‐analysis of patients with HF and reduced, mildly reduced, and preserved ejection fraction (HFrEF, HFmrEF, and HFpEF, respectively) enrolled in eight large randomized trials. Overall, the proportion of octogenarians was 1518 of 20 168 patients (7.5%) with HFrEF, 610 of 4609 (13.2%) with HFmrEF, and 3130 of 15 354 (20.4%) with HFpEF. Regardless of HF phenotype, octogenarian patients were more often female and had more comorbidities, more symptoms and signs of congestion, and worse health status (but not quality of life), in comparison to patients aged <80 years. The incidence (per 100 person‐years) of the composite of cardiovascular death or HF hospitalization was 13.3 (95% confidence interval [CI] 12.7–14.0) in octogenarians versus 9.5 (95% CI 9.3–9.7) in non‐octogenarians (adjusted hazard ratio [aHR] 1.40, 95% CI 1.32–1.48). Each component of the composite was more frequent in octogenarians with rates of cardiovascular mortality of 7.0 (95% CI 6.5–7.4) per 100 person‐years versus 4.9 (95% CI 4.8–5.1) in non‐octogenarians (aHR 1.60, 95% CI 1.48–1.72, p < 0.001). Octogenarians received less evidence‐based therapy, especially mineralocorticoid receptor antagonists, than younger patients.ConclusionDespite worse health status and higher hospitalization and mortality rates, octogenarians were undertreated compared to younger patients.
Heavy Atom Quantum Tunnelling in N‐Heterocyclic Pentalenes
Authors: Santoyo‐Flores Juan Julian , Kozuch Sebastian 
Published: August 2024

AbstractHeavy atom quantum tunnelling was already observed in several π‐bond‐shifting reactions of antiaromatic molecules. In these, their Jahn‐Teller distortions create sharp energy profiles with small atomic trajectories, which are ideal for observing tunnelling. Herein, we studied the effect of the nitrogen in the N‐heterocyclic pentalenes, distinguishing between isothermic and exothermic reactions. The reactivity was not easily predictable, with our computations revealing a wide variability of rates, from the complete cancellation of the barrier to high isomer stability. For all these systems, quantum tunnelling emerged as the most significant mechanism at room temperature and the only valid one at cryogenic conditions.
Research on the prevention and manage of rockburst in deep‐seam mining roadways
Authors: Huang Wanpeng , Zhao Tongyang , Jiang Donghai , Liu Yaxin , Wang Xukui , Xin Guangming 
Published: August 2024

AbstractThis study presents a strategy for preventing and controlling rockbursts in deep and vast seams during the mining operation. We analyzed the main factors influencing rockburst by combining the geological structure of the rock mass with field‐collected microseismic monitoring data. Determined the disturbance strain sensitive threshold through mechanical experiments on coal's antidisturbance characteristics, the indoor pull‐out test of the supporting bolt was carried out. Studied the rockburst support technology and the antirockburst capability of the support system based on the energy method. The key governing variables of regional impact risk in the big buried deep coal seam operating face include high tectonic stress, goaf effect, fault, and fault protection coal pillar. The uniaxial compressive strength of the coal sample in the 3308 working face is 15.11 MPa, the antidisturbance strength is 10 MPa. When the extreme stress is 86.03%, the specimen fails; the ultimate failure strength under disturbance is 13 MPa. The support system's antishock ability is analyzed based on its energy absorption, under the premise of ensuring the support quality and support strength, the antiscour ability of 3308 Tailentry support meets the anti‐impact requirements. It is believed that the system offers adequate lateral confining pressure for the internal creep disturbance‐sensitive area, enhancing the area's resistance to disturbance. This is crucial in preventing and managing rockburst incidents.
LETKF‐based Ocean Research Analysis (LORA) version 1.0
Authors: Ohishi Shun , Miyoshi Takemasa , Ando Takafusa , Higashiuwatoko Tomohiko , Yoshizawa Eri , Murakami Hiroshi , Kachi Misako 
Published: August 2024

AbstractLocal ensemble transform Kalman filter (LETKF)‐based Ocean Research Analysis (LORA) version 1.0 datasets for western North Pacific (WNP) and Maritime Continent (MC) regions (LORA‐WNP and ‐MC, respectively) are released through the JAXA‐RIKEN Ocean Analysis website. The LORA datasets are created using an eddy‐resolving LETKF‐based ocean data assimilation system with satellite sea‐surface temperature, salinity, and height data and with in‐situ temperature and salinity data assimilated daily. The LORA datasets include 128‐member ensemble analyses at the sea surface (2D), each term of mixed‐layer temperature and salinity budget equations, and the related variables (2D) such as mixed‐layer depth and heat and freshwater fluxes as well as system grid information and analysis ensemble mean and spread (3D), from August 2015 to January 2024 (as of June 2024). The LORA datasets are useful for geoscience research and practical applications, especially for particle tracking, boundary conditions of atmospheric models, and research on spatiotemporal variations in sea‐surface temperature and salinity.
An Exploration of the Peri‐Diagnostic Experiences of Lesbian, Gay and Bisexual People With Dementia Using the Candidacy Framework
Authors: Hammond J. , Hicks B. , Daley S. , Banerjee S. 
Published: August 2024

ABSTRACTObjectivesHow dementia affects lesbian, gay, bisexual, trans, queer people or those with other minoritised sexual/gender identities (LGBTQ+) is not well understood. Furthermore, existing research often excludes the voices of LGBTQ+ people living with dementia and focuses instead on their care partners. This study addresses this evidence gap by drawing on the ESRC/NIHR funded DETERMIND cohort, consisting of 940 newly diagnosed people with dementia, to explore the peri‐diagnostic experiences of people living with dementia who identify as LGBTQ+.MethodsWe recruited five people (who identified as lesbian, gay or bisexual [LGB]) and completed semi‐structured interviews with them and their partner caregivers (n = 3) discussing their experiences of (1) engaging with dementia health care services, (2) receiving a dementia diagnosis, and (3) the support they were offered after diagnosis. Interviews were shaped by the Candidacy Framework, a theoretical model for understanding accessibility of health services, and an inductive thematic analysis was employed to develop common themes.FindingsParticipants did not routinely disclose their LGBTQ+ identities to health service professionals, despite feeling this was an essential aspect of who they are. They relied on their resilience of overcoming previous experiences of lifetime discrimination to navigate complicated dementia care systems. The importance of ‘chosen families’ as informal support networks for LGBTQ+ people living with dementia was highlighted, particularly given the lack of formal care services they felt comfortable accessing. All participants were concerned about their future care needs and whether they would receive home‐based or community‐based support that respected their LGBTQ+ identities.ConclusionsThis study adds to the limited evidence base that can be used to inform future research, policy and practice seeking to address inequalities across the dementia care pathway. We only interviewed people who identified as LGB so generalizability to the whole LGBTQ+ population is limited, however our data suggest dementia health care professionals should encourage and support disclosures of LGBTQ+ identities so that inclusive care and support planning can be provided to LGBTQ+ people at every stage of dementia.
Exploring the interplay between epicardial fat, coronary artery calcium score, and nonalcoholic fatty liver disease through non‐ECG‐gated chest computed tomography: A cross‐sectional study
Authors: Moradi Golnaz , Abed Aisen , Zarei Diana , Ashraf Haleh , Asefi Hoda 
Published: August 2024

AbstractBackground and AimsThis study examines the relationships between epicardial adipose tissue (EAT), nonalcoholic fatty liver disease (NAFLD), and coronary artery calcium score (CACS) using non‐ECG‐gated CT scans. It aims to determine the effectiveness of EAT measurements and NAFLD as predictors for coronary artery disease (CAD).MethodsThis cross‐sectional study was conducted at a specialized center, focusing on individuals who underwent non‐ECG‐gated chest CT scans without contrast. We evaluated EAT thickness and density in three areas: the right atrioventricular groove, the free wall of the right ventricle, and the central area of the right anterior interventricular groove. Additionally, we measured CACS and determined the presence of NAFLD by comparing liver‐to‐spleen density ratios. Statistical analyses, including regression models, were performed using SPSS (version 26).ResultsIn this study, we enrolled 365 participants, including 203 males with an average age of 47 ± 17.93 years. EAT thickness was 6.28 ± 1.62 mm, and EAT density was −96.07 ± 12.47 Hounsfield units (HU). The mean CACS was 22.27 ± 79.01, and the mean liver density was 50.01 ± 10.76 HU. A significant positive correlation was observed between EAT thickness and CACS (r = 0.208, p < 0.001). EAT density showed a significant negative correlation with CACS (r = −0.155, p = 0.003). No correlation was found between NAFLD and CACS. Univariate logistic regression analysis identified significant predictors of increased CACS, including EAT thickness (OR: 1.803), EAT density (OR: 0.671), diabetes mellitus (DM) (OR: 5.921), and hypertension (HTN) (OR: 7.414). Multivariate analysis confirmed the significance of EAT thickness (OR: 0.682), DM (OR: 3.66), and HTN (OR: 2.79) as predictors of elevated CACS.ConclusionOur findings demonstrate that increased EAT thickness and decreased density are associated with higher CACS. Also, both DM and HTN significantly contribute to increased CACS. These results support the inclusion of EAT measurements in cardiovascular risk assessment models to enhance diagnostic accuracy.
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Authors: Wang Qiang , Wang Yachuan , Wang Yankun , Jiang Luyue , Zhao Jinyan , Song Zhitang , Bi Jinshun , Zhao Libo , Jiang Zhuangde , Schwarzkopf Jutta , Wu Shengli , Zhang Bin , Ren Wei , Song Sannian , Niu Gang 
Published: August 2024

Hardware neuromorphic computing based on phase‐change random access memories brings about a spring of artificial intelligence.
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Maps or Itineraries? A Systems Engineering Insight from Ancient Navigators
Authors: Schindel William D. 
Published: August 2024

ABSTRACTProcesses and procedures are the heart of current descriptions of systems engineering. The “vee diagram,” ISO 15288, the INCOSE Systems Engineering Handbook, and enterprise‐specific business process models focus attention on process and procedure. However, there is a non‐procedural way to view systems engineering. This approach is to describe the configuration space “navigated” by systems engineering, and what is meant by system trajectories in that space, traveled during system life cycles. This sounds abstract because we have lacked explicit maps necessary to describe this configuration space. We understand concrete steps of a procedure, so we focus there. But where do these steps take us? And what does “where” mean in this context? Clues are found in recent discoveries about ancient navigation, as well as later development of mathematics and physics. This paper, part I of a case for stronger model‐based systems engineering (MBSE) semantics, focuses on the underlying configuration space inherent to systems.
Observation on the developmental studies of stomatal differentiation in the epidermis of Solanaceae
Authors: Karatela Y. Y. , Gill L. S. 
Published: August 2024

SummaryEpidermal morphology and development of stomata in 15 species of the family Solanacene are described. Hemimesogenous ontogeny with single subsidiary cell is described for anomocytic, diacytic, anisocytie and paracytic stomata. Ontogeny of anisocytic stomata with two mesogene subsidiary cells is traced in Lycopersicon esculentum and Nicotiana tabacum. Contiguous stomata and cytoplasmic connections between adjacent guard cells are observed in Capsicum annuum and Lycopersicon esculentum. Definite relationship exists between sinousity of epidermal cells and growth habit.
Implementation and evaluation of a patient action plan for patients with atopic dermatitis
Authors: Thormann K. , Lupe L. , Radonjic‐Hoesli S. , von Dach C. , Simon D. 
Published: August 2024

AbstractBackgroundManagement and treatment of atopic dermatitis (AD) are complex and therefore bear the risk of therapeutic failure. Individualised patient action plans for patients and for caregivers have been shown to improve AD management, eczema monitoring and therapy adherence. Little is known about the use of patient action plans in the adult setting.ObjectivesThis project aimed at implementing a patient action plan to improve eczema management and evaluating its effects on disease severity and patient‐related outcomes.MethodsThis quality improvement project had a pretest–posttest design and evaluated AD severity and patient‐related outcomes after implementing a patient action plan. A convenience sample of 20 adult patients with AD was included. Socio‐demographic, diagnostic and clinical variables were collected from the electronic health records. Trained staff assessed AD severity using SCORing Atopic Dermatitis (SCORAD) and person‐centred dermatology self‐care index (PeDeSI‐G) pre as well as 1‐month postintervention. Patients completed dermatology life quality index (DLQI) and patient benefit index (PBI). For comparison of SCORAD, DLQI, PeDeSI‐G, paired t‐test was applied. PBI was presented using descriptive statistics.ResultsUpon intervention, a significant decrease of disease severity (p < 0.0001), in parallel with a significant decrease of DLQI (p < 0.001) and PeDeSI‐G (p < 0.0001) was observed. A PBI ≥ 1 was reached in 95% of participants (mean 2.73; SD 0.9).ConclusionsOur findings confirm the importance of providing patient action plans to AD patients to achieve best treatment results. Based on our experience, we plan to modify the action plan by including both topical and systemic therapies, and to translate it into several languages.