bluuebunny/crossref_metadata_2025_split huggingface dataset:
Four-Week Prevalence of Mental Disorders in Patients With Cancer Across Major Tumor Entities
Authors: Mehnert Anja , Brähler Elmar , Faller Hermann , Härter Martin , Keller Monika , Schulz Holger , Wegscheider Karl , Weis Joachim , Boehncke Anna , Hund Bianca , Reuter Katrin , Richard Matthias , Sehner Susanne , Sommerfeldt Sabine , Szalai Carina , Wittchen Hans-Ulrich , Koch Uwe 
Published: October 2014

Purpose To provide the 4-week prevalence estimates of mental disorders in cancer populations. Patients and Methods We enrolled adult patients with cancer from in- and outpatient care facilities, using a proportional stratified random sample based on the nationwide cancer incidence in Germany. Patients who scored 9 or above on the Patient Health Questionnaire (PHQ-9) were administered to the standardized computer-assisted Composite International Diagnostic Interview for mental disorders adapted for cancer patients (CIDI-O). A random sample of those with a PHQ-9 score that was less than 9 were selected for a CIDI-O. Results A total of 5,889 patients were identified, which led to 4,020 participants (a 68.3% response rate); of those, 2,141 patients were interviewed. The 4-week total prevalence for any mental disorder was 31.8% (95% CI, 29.8% to 33.8%); this included any anxiety disorder (11.5%; 95% CI, 10.2% to 12.9%), any adjustment disorder (11.1%; 95% CI, 9.7% to 12.4%), any mood disorder (6.5%; 95% CI, 5.5% to 7.5%), any somatoform/conversion disorder (5.3%; 95% CI, 4.3% to 6.2%), nicotine dependence (4.5%; 95% CI, 3.6% to 5.4%), alcohol abuse/dependence (0.3%; 95% CI, 0.1% to 0.6%), any mental disorder resulting from general medical condition (2.3%; 95% CI, 1.7% to 2.9%), and any eating disorder (0%). The highest prevalence for any mental disorder was found in patients with breast cancer (41.6%; 95% CI, 36.8% to 46.4%), followed by patients with head and neck cancer (40.8%; 95% CI, 28.5% to 53.0%). The lowest prevalence was found in patients with pancreatic cancer (20.3%; 95% CI, 8.9% to 31.6%) and stomach/esophagus cancers (21.2%; 95% CI, 12.8% to 29.6%). Conclusion Our findings provide evidence for the strong need for psycho-oncological interventions.
Postinduction Minimal Residual Disease Monitoring by Polymerase Chain Reaction in Children With Acute Lymphoblastic Leukemia
Authors: Paganin Maddalena , Fabbri Giulia , Conter Valentino , Barisone Elena , Polato Katia , Cazzaniga Giovanni , Giraldi Eugenia , Fagioli Franca , Aricò Maurizio , Valsecchi Maria Grazia , Basso Giuseppe 
Published: October 2014

Purpose Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer. Monitoring minimal residual disease (MRD) by using real-time quantitative polymerase chain reaction (RQ-PCR) provides information for patient stratification and individual risk-directed treatment. Cooperative studies have documented that measurement of blast clearance from the bone marrow during and after induction therapy identifies patient populations with different risk of relapse. We explored the possible contribution of measurements of MRD during the course of treatment. Patients and Methods We used RQ-PCR to detect MRD in 110 unselected patients treated in Italy in the International Collaborative Treatment Protocol for Children and Adolescents With Acute Lymphoblastic Leukemia (AIEOP-BFM ALL 2000). The trial took place in AIEOP centers during postinduction chemotherapy. Results were categorized as negative, low positive (below the quantitative range [< 5 × 10−4]), or high positive (≥ 5 × 10−4). Patients with at least one low-positive or high-positive result were assigned to the corresponding subgroup. Results Patients who tested high positive, low positive, or negative had significantly different cumulative incidences of leukemia relapse: 83.3%, 34.8%, and 8.6%, respectively (P < .001). Two thirds of positive cases were identified within 4 months after induction-consolidation therapy, suggesting that this time frame may be most suitable for cost-effective MRD monitoring, particularly in patients who did not clear their disease at the end of consolidation. Conclusion These findings provide further insights into the dynamic of MRD and the ongoing effort to define molecular relapse in childhood ALL.
Individual Prediction of Heart Failure Among Childhood Cancer Survivors
Authors: Chow Eric J. , Chen Yan , Kremer Leontien C. , Breslow Norman E. , Hudson Melissa M. , Armstrong Gregory T. , Border William L. , Feijen Elizabeth A.M. , Green Daniel M. , Meacham Lillian R. , Meeske Kathleen A. , Mulrooney Daniel A. , Ness Kirsten K. , Oeffinger Kevin C. , Sklar Charles A. , Stovall Marilyn , van der Pal Helena J. , Weathers Rita E. , Robison Leslie L. , Yasui Yutaka 
Published: October 2014

PurposeTo create clinically useful models that incorporate readily available demographic and cancer treatment characteristics to predict individual risk of heart failure among 5-year survivors of childhood cancer.Patients and MethodsSurvivors in the Childhood Cancer Survivor Study (CCSS) free of significant cardiovascular disease 5 years after cancer diagnosis (n = 13,060) were observed through age 40 years for the development of heart failure (ie, requiring medications or heart transplantation or leading to death). Siblings (n = 4,023) established the baseline population risk. An additional 3,421 survivors from Emma Children's Hospital (Amsterdam, the Netherlands), the National Wilms Tumor Study, and the St Jude Lifetime Cohort Study were used to validate the CCSS prediction models.ResultsHeart failure occurred in 285 CCSS participants. Risk scores based on selected exposures (sex, age at cancer diagnosis, and anthracycline and chest radiotherapy doses) achieved an area under the curve of 0.74 and concordance statistic of 0.76 at or through age 40 years. Validation cohort estimates ranged from 0.68 to 0.82. Risk scores were collapsed to form statistically distinct low-, moderate-, and high-risk groups, corresponding to cumulative incidences of heart failure at age 40 years of 0.5% (95% CI, 0.2% to 0.8%), 2.4% (95% CI, 1.8% to 3.0%), and 11.7% (95% CI, 8.8% to 14.5%), respectively. In comparison, siblings had a cumulative incidence of 0.3% (95% CI, 0.1% to 0.5%).ConclusionUsing information available to clinicians soon after completion of childhood cancer therapy, individual risk for subsequent heart failure can be predicted with reasonable accuracy and discrimination. These validated models provide a framework on which to base future screening strategies and interventions.
Musielak–Orlicz Hardy Spaces Associated with Divergence Form Elliptic Operators Without Weight Assumptions
Authors: Tran Tri Dung 
Published: October 2014

AbstractLet L be a divergence form elliptic operator with complex bounded measurable coefficients, let ω be a positive Musielak-Orlicz function on (0, ∞) of uniformly strictly critical lower-type pω ∈ (0, 1], and let ρ(x,t) = t−1/ω−1 (x,t−1) for x ∈ ℝn, t ∊ (0, ∞). In this paper, we study the Musielak-Orlicz Hardy space Hω,L(ℝn) and its dual space BMOρ,L* (ℝ n), where L* denotes the adjoint operator of L in L2 (ℝ n). The ρ-Carleson measure characterization and the John-Nirenberg inequality for the space BMOρ,L (ℝn) are also established. Finally, as applications, we show that the Riesz transform ∇L−1/2 and the Littlewood–Paley g-function gL map Hω,L(ℝn) continuously into L(ω).
One-pot In Situ Synthesis of Hollow Layered Double Hydroxide–Ammonium Polyphosphate Nanoshells toward Flame Retardant
Authors: Li Zhangcheng , Xue Zhonghua , Yang Baojun , Wang Bainian , Peng Xinhua 
Published: October 2014

Abstract
A novel approach to synthesize nanostructure composites of layered double hydroxide–ammonium polyphosphate (LDH–APP) is reported. hollow LDH–APP nanoshells were synthesized by simply mixing precursor solutions and systematically characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD), Fourier transform infrared (FTIR), and Brunauer–Emmett–Teller (BET) techniques. The as-fabricated LDH–APP–PP (polypropylene) composites using hollow LDH–APP nanoshells as nanofiller show excellent flame-retardant performance, which is much better than that of LDH–PP. It is expected that such a kind of LDH–APP composite materials may have potential applications in the field of industrial flame-retardant.
Simple Homopolymer-incarcerated Gold Nanoclusters Prepared by Self-assembled Encapsulation with Aluminum Reagents as Crosslinkers: Catalysts for Aerobic Oxidation Reactions
Authors: Yasukawa Tomohiro , Miyamura Hiroyuki , Kobayashi Shū 
Published: October 2014

Abstract
Simple homopolymer-incarcerated gold nanocluster catalysts were developed using a self-assembled encapsulation strategy. In this method, Red-Al® acting as a reductant also played the role of an inter-crosslinker via the formation of tetraalkoxyaluminate with the hydroxy groups in a homopolymer. Gold nanoclusters could be immobilized at high loadings without aggregation, and high catalytic activities were observed in several aerobic oxidation reactions.
Predictors of eating disorders outcomes in Polish teenage patients
Authors: Pilecki Maciej , Józefik Barbara , Solecka Dorota , Cygankiewicz Patrycja 
Published: October 2014

Aim of the studyThe aim of this study was to assess factors associated with outcome of eating disorders in Polish teenage patients.Subject or material and methodsAnalyses covered the data of 47 patients diagnosed with any of the eating disorders according to DSM IV consulted for the first time in the outpatients clinic of the Child and Adolescent Psychiatry Unit between 2002/2004 in Krakow (DGN1), Poland and then followed-up between 2009/2011 (DGN2). The influence of the number of variables collected at DGN1 on outcomes were analysed.ResultsThe outcomes of anorexia nervosa and bulimia nervosa are influenced by some aspects of clinical picture, patients’ objective family situation, their self-image and the perception they have of their family relations. The co-occurrence of depressive symptoms and younger age of parents proved to be the most clinically important negative outcome predictors in whole group of eating disorders.DiscussionSmall size of group in the follow-up study is the most important limitating factor.ConclusionsConclusion: Outcomes in eating disorders are affected by several psycho-bio-social factors common for all patients and specific for diagnosis type they initially present.
Autoprezentacja cesarzy rzymskich w mennictwie II i III wieku po Chr.
Authors: Balbuza Katarzyna 
Published: October 2014

Recenzja książki: Erika Manders, Coining Images of Power. Patterns in the Representation of Roman Emperors on Imperial Coinage A.D. 193––284, Brill Academic Publishers, Leiden–Boston–Tokyo 2012 [=Impact of Empire, 15], 363 s.
Hamiltonian stability of Hamiltonian minimal Lagrangian submanifolds in pseudo- and para-Kähler manifolds
Authors: Anciaux Henri , Georgiou Nikos 
Published: October 2014

Abstract
Let L be a Lagrangian submanifold of a pseudo- or para-Kähler manifold with nondegenerate induced metric which is H-minimal, i.e. a critical point of the volume functional restricted to Hamiltonian variations. We derive the second variation formula of the volume of L with respect to Hamiltonian variations and apply this formula to several cases. We observe that a minimal Lagrangian submanifold L in a Ricci-flat pseudo- or para-Kähler manifold is H-stable, i.e. its second variation is definite and L is in particular a local extremizer of the volume with respect to Hamiltonian variations. We also give a stability criterion for spacelike minimal Lagrangian submanifolds in para-Kähler manifolds, similar to Oh’s stability criterion for minimal Lagrangian manifolds in Kähler-Einstein manifolds (cf. [20]). Finally, we determine the H-stability of a series of examples of H-minimal Lagrangian submanifolds: the product S1(r1) x ··· x S1(rn) of n circles of arbitrary radii in complex space Cn is H-unstable with respect to any indefinite flat Hermitian metric, while the product ℍ1(r1) x ···x ℍ1(rn) of n hyperbolas in para-complex vector space Dn is H-stable for n = 1; 2 and H-unstable for n ≥ 3. Recently, minimal Lagrangian surfaces in the space of geodesics of space forms have been characterized ([4], [11]); on the other hand, a class of H-minimal Lagrangian surfaces in the tangent bundle of a Riemannian, oriented surface has been identified in [6]. We discuss the H-stability of all these examples.
A multimodel inference approach to categorical variant choice: construction, priming and frequency effects on the choice between full and contracted forms of am, are and is
Authors: Barth Danielle , Kapatsinski Vsevolod 
Published: October 2014

AbstractThe present paper presents a multimodel inference approach to linguistic variation, expanding on prior work by Kuperman and Bresnan (2012). We argue that corpus data often present the analyst with high model selection uncertainty. This uncertainty is inevitable given that language is highly redundant: every feature is predictable from multiple other features. However, uncertainty involved in model selection is ignored by the standard method of selecting the single best model and inferring the effects of the predictors under the assumption that the best model is true. Multimodel inference avoids committing to a single model. Rather, we make predictions based on the entire set of plausible models, with contributions of models weighted by the models' predictive value. We argue that multimodel inference is superior to model selection for both the I-Language goal of inferring the mental grammars that generated the corpus, and the E-Language goal of predicting characteristics of future speech samples from the community represented by the corpus. Applying multimodel inference to the classic problem of English auxiliary contraction, we show that the choice between multimodel inference and model selection matters in practice: the best model may contain predictors that are not significant when the full set of plausible models is considered, and may omit predictors that are significant considering the full set of models. We also contribute to the study of English auxiliary contraction. We document the effects of priming, contextual predictability, and specific syntactic constructions and provide evidence against effects of phonological context.
What's in a dialogic construction? A constructional approach to polysemy and the grammar of challenge
Authors: Nikiforidou Kiki , Marmaridou Sophia , Mikros George K. 
Published: October 2014

AbstractIn this paper we address lexical polysemy in a constructional perspective, arguing that each of the conversational meanings we identify for Modern Greek ela (2nd person singular imperative of the verb erxome ‘come’) is appropriately modeled as a conceptual gestalt of formal (including prosodic) and semantic-pragmatic properties. In turn-initial position, ela is used to challenge a preceding utterance; we show that the variations in the kind of challenge expressed are systematically tied to the word that follows ela, the speech act force and the sentence type of the preceding utterance, and finally prosodic and textual cues. To the extent that these varieties of conversational challenge are conditioned by particular contextual features, we treat them as a family of related constructions whose common features can be captured in the form of a generalized ela construction abstracted from the different sub-patterns. Our analysis thus demonstrates the appropriateness of a constructional framework for dealing with the different kinds of parameters involved in dialogic meaning and strongly suggests that at least some of the variation inherent in discourse is amenable to a grammatical description, so that sentence-level and supra-clause patterns can be analyzed in a uniform way.
Chloral hydrate, through biotransformation to dichloroacetate, inhibits maleylacetoacetate isomerase and tyrosine catabolism in humans
Authors: Shroads Albert L. , Coats Bonnie S. , Langaee Taimour , Shuster Jonathan J. , Stacpoole Peter W. 
Published: October 2014

Abstract

Background: Chloral hydrate (CH), a sedative and metabolite of the environmental contaminant trichloroethylene, is metabolized to trichloroacetic acid, trichloroethanol, and possibly dichloroacetate (DCA). DCA is further metabolized by glutathione transferase zeta 1 (GSTZ1), which is identical to maleylacetoacetate isomerase (MAAI), the penultimate enzyme in tyrosine catabolism. DCA inhibits its own metabolism through depletion/inactivation of GSTZ1/MAAI with repeated exposure, resulting in lower plasma clearance of the drug and the accumulation of the urinary biomarker maleylacetone (MA), a metabolite of tyrosine. It is unknown if GSTZ1/MAAI may participate in the metabolism of CH or any of its metabolites and, therefore, affect tyrosine catabolism. Stable isotopes were utilized to determine the biotransformation of CH, the kinetics of its major metabolites, and the influence, if any, of GSTZ1/MAAI.

Methods: Eight healthy volunteers (ages 21–40 years) received a dose of 1 g of CH (clinical dose) or 1.5 μg/kg (environmental) for five consecutive days. Plasma and urinary samples were analyzed by gas chromatography-mass spectrometry.

Results: Plasma DCA (1.2–2.4 μg/mL), metabolized from CH, was measured on the fifth day of the 1 g/day CH dosage but was undetectable in plasma at environmentally relevant doses. Pharmacokinetic measurements from CH metabolites did not differ between slow and fast GSTZ1 haplotypes. Urinary MA levels increased from undetectable to 0.2–0.7 μg/g creatinine with repeated CH clinical dose exposure. Kinetic modeling of a clinical dose of 25 mg/kg DCA administered after 5 days of 1 g/day CH closely resembled DCA kinetics obtained in previously naïve individuals.

Conclusions: These data indicate that the amount of DCA produced from clinically relevant doses of CH, although insufficient to alter DCA kinetics, is sufficient to inhibit MAAI and tyrosine catabolism, as evidenced by the accumulation of urinary MA.
Polyfunctionality and transcategoriality of coordinating particles in Latin and in other ancient languages
Authors: Orlandini Anna , Poccetti Paolo 
Published: October 2014

AbstractSemantic and pragmatic values of Latin coordinators will be analyzed in comparison with other ancient languages under the following conditions: (a) in an asymmetrical sequence, where they may express temporal relations (‘and then’) or causal relations (‘and so’); (b) in dialogic verbal interaction in their cognitive effects and their informational and rhetorical contributions; (c) with respect to their position and their role in the discourse organization; (d) in the sentence- or utterance-initial position, as discourse markers for repetition, reformulation, expressive intensity, indignation, or denial of an expectation, depending on the different interpretive effects arising from different contexts.Initial position provides a privileged position for expressions associated with speakers' intervention, emotions, mental reservations, and disagreement. Coordinators thus give rise to conversational implicatures (Grice 1975), pragmatically determined by each context. The initial position of coordinators is thus of decisive importance from the point of view of multifunctionality and discursive interchange.
Latin parts of speech in historical and typological context
Authors: Viti Carlotta 
Published: October 2014

AbstractIt is usually assumed that Latin parts of speech cannot be properly applied to other languages, especially outside the Indo-European domain. We will see, however, that the traditional distinction into eight parts of speech is established only in the late period of the classical school of grammar, while originally parts of speech varied in number and in type according to different grammarians, as well as to different periods and genres. Comparisons will be drawn on the one hand with parts of speech in the Greek and Indian tradition, and on the other with genetically unrelated languages where parts of speech – notably adjectives and adverbs – are scarcely grammaticalized. This may be revealing of the manner in which the ancients used to categorize their language.
Taxonomic evaluation of the bent-winged bat (Miniopterus) populations occurring in Iran inferred from mitochondrial cytochrome-b sequences
Authors: Akmali Vahid , Mehdizadeh Robab , Chaghamirza Kianoosh , Moradi Marziyeh , Sharifi Mozafar 
Published: October 2014

AbstractWe studied the genetic differentiation and taxonomy of the bent-wing bat (
Nanomaterials for boron and gadolinium neutron capture therapy for cancer treatment
Authors: Gao Shanmin , Fu Rongrong , Hosmane Narayan S. 
Published: October 2014

Abstract
Cancer is one of the leading causes of death; with it may different types, it kills thousands of people every day. Various types of treatment have been developed to treat and cure cancer. Nanotechnology has emerged as one of the most fruitful areas of science in cancer treatment and the nanomaterials are considered as a medical boon for the diagnosis, treatment and prevention of cancer. The major approaches of nanotechnology in tumor treatment include the development of nanoparticles with less or no tissue-resistance, their biocompatibility, ability as nanocarriers for drug delivery, and enhanced energy deposition in tissue with or without the external influence of microwave, light, magnet, etc. This review presents some of the recent developments in the use of nanoparticles as adjuncts to boron and gadolinium containing compounds in boron neutron capture therapy (BNCT) and gadolinium neutron capture therapy (GdNCT) along with the latest developments in the area of boron nanotubes (BNTs), gadolinium oxide, boron nitride nanotubes (BNNTs) and the boron agent itself.
Economic Growth and Recovery After Civil Wars
Authors: Gil-Alana Luis A. , Singh Prakarsh 
Published: October 2014

AbstractUsing a fractional integration approach, we find that developing countries recover their economic growth faster than developed countries in response to a shock. The main finding is that longer civil conflicts are associated with a faster recovery process. To investigate deeper on this issue, we explore correlations with components of GDP. Higher government spending is correlated with faster recoveries post longer conflicts and higher consumption and investment are linked to faster recoveries following shorter conflicts.
Military Expenditure and Investment in OECD Countries: Revisited
Authors: Hou Na , Chen Bo 
Published: October 2014

AbstractThis study examines the effects of military expenditure on investment in 13 selected OECD countries over the period of 1971–2012 by applying the Smith Demand-Side model and different estimation methodologies including panel data, cross section and time series estimation methods. Our empirical results reveal that military expenditure crowds out investment and that crowding-out effect lessens during the Post-Cold War period.
Sputter-Deposited Mg-Zr Alloys – Surface Characteristics and Electrochemical Behavior in Borate Solutions
Authors: El-Moneim Ahmed Abd , Ismail Khalid Mahfouz , Badawy Waheed Abdallah 
Published: October 2014

Abstract
The effect of zirconium on the electrochemical kinetics and surface
characteristics of Mg-(6 – 81 at %) Zr alloys
was investigated by different electrochemical techniques. The
sputter-deposited alloy is subjected to X-ray photo-electron
spectroscopic analyses. Alloys with ≥ 29 at % Zr were
spontaneously passivated. The passive film resistance is much higher
than that formed on Mg metal. The high resistance of the
passive film was attributed to a continuous connected network of
a double oxy-hydroxide composed mainly of Zr4+ and a small
amount of Mg2+. XPS measurements revealed a dynamic nature
of the passive film, where concentration gradient of Zr4+,
Mg2+, OH
–
and O2–
species was recorded
throughout a few nanometers depth. An optimum Zr content is
required to promote the formation of stable oxy-hydroxide film. Alloys
with Zr content ≥ 29 at % attains critical oxide
film composition with Zr4+ ≥ 0.69 cation fractions and
thickness in the range of 3.2 ∼ 4.5 nm.