bluuebunny/crossref_metadata_2025_split huggingface dataset:
Use of an Insulin Bolus Advisor Improves Glycemic Control in Multiple Daily Insulin Injection (MDI) Therapy Patients With Suboptimal Glycemic Control
Authors: Ziegler Ralph , Cavan David A. , Cranston Iain , Barnard Katharine , Ryder Jacqueline , Vogel Claudia , Parkin Christopher G. , Koehler Walter , Vesper Iris , Petersen Bettina , Schweitzer Matthias A. , Wagner Robin S. 
Published: July 2013

OBJECTIVE
Use of automated bolus advisors is associated with improved glycemic control in patients treated with insulin pump therapy. We conducted a study to assess the impact of using an insulin bolus advisor embedded in a blood glucose (BG) meter on glycemic control and treatment satisfaction in patients treated with multiple daily insulin injection (MDI) therapy. The study goal was to achieve &gt;0.5% A1C reduction in most patients.

RESEARCH DESIGN AND METHODS
This was a 26-week, prospective, randomized, controlled, multinational study that enrolled 218 MDI-treated patients with poorly controlled diabetes (202 with type 1 diabetes, 16 with type 2 diabetes) who were 18 years of age or older. Participants had mean baseline A1C of 8.9% (SD, 1.2 [74 mmol/mol]), mean age of 42.4 years (SD, 14.0), mean BMI of 26.5 kg/m2 (SD, 4.2), and mean diabetes duration of 17.7 years (SD, 11.1). Control group (CNL) patients used a standard BG meter and manual bolus calculation; intervention group (EXP) patients used the Accu-Chek Aviva Expert meter with an integrated bolus advisor to calculate insulin dosages. Glucose data were downloaded and used for therapy parameter adjustments in both groups.

RESULTS
A total of 193 patients (CNL, n = 93; EXP, n = 100) completed the study. Significantly more EXP than CNL patients achieved &gt;0.5% A1C reduction (56.0% vs. 34.4%; P &lt; 0.01). Improvement in treatment satisfaction (Diabetes Treatment Satisfaction Questionnaire scale) was significantly greater in EXP patients (11.4 [SD, 6.0] vs. 9.0 [SD, 6.3]; P &lt; 0.01). Percentage of BG values &lt;50 mg/dL was &lt;2% in both groups during the study.

CONCLUSIONS
Use of an automated bolus advisor resulted in improved glycemic control and treatment satisfaction without increasing severe hypoglycemia.
Assessment Method of Overheating Degree of a Spent Moulding Sand with Organic Binder, After the Casting Process
Authors: Dańko R. 
Published: July 2013

Abstract
A proper management of sand grains of moulding sands requires knowing basic properties of the spent matrix after casting knocking out. This information is essential from the point of view of the proper performing the matrix recycling process and preparing moulding sands with reclaimed materials. The most important parameter informing on the matrix quality - in case of moulding sands with organic binders after casting knocking out - is their ignition loss. The methodology of estimating ignition loss of spent moulding sands with organic binder - after casting knocking out - developed in AGH, is presented in the paper. This method applies the simulation MAGMA software, allowing to determine this moulding sand parameter already at the stage of the production preparation.
Mould Components Impact on Structure and Quality of Elektron 21 Alloy
Authors: Dybowski B. , Kiełbus A. , Jarosz R. 
Published: July 2013

Abstract
Magnesium alloys due to their low density and high strength-to-weight ratio are promising material for the automotive and aerospace industries. Many elements made from magnesium alloys are produced by means of sand casting. It is essential to investigate impact of the applied mould components on the microstructure and the quality of the castings. For the research, six identical, 100x50x20mm plates has been sand cast from the Elektron 21 magnesium casting alloy. Each casting was fed and cooled in a different way: one, surrounded by mould sand, two with cast iron chills 20mm and 40mm thick applied, another two with the same chills as well as feeders applied and one with only the feeder applied. Solid solution grain size and eutectics volume fraction were evaluated quantitatively in Met-Ilo program, casting defects were observed on the scanning electron microscope Hitachi S3400N. The finest solid solution grain was observed in the castings with only the chills applied. Non metallic inclusions were observed in each plate. The smallest shrinkage porosity was observed in the castings with the feeders applied.
Influence of the Training Set Value on the Quality of the Neural Network to Identify Selected Moulding Sand Properties
Authors: Jakubski J. , Dobosz St. M. , Major-Gabryś K. 
Published: July 2013

Abstract
Artificial neural networks are one of the modern methods of the production optimisation. An attempt to apply neural networks for controlling the quality of bentonite moulding sands is presented in this paper. This is the assessment method of sands suitability by means of detecting correlations between their individual parameters. This paper presents the next part of the study on usefulness of artificial neural networks to support rebonding of green moulding sand, using chosen properties of moulding sands, which can be determined fast. The effect of changes in the training set quantity on the quality of the network is presented in this article. It has been shown that a small change in the data set would change the quality of the network, and may also make it necessary to change the type of network in order to obtain good results.
Effect of Nickel Equivalent on Austenite Transition Ratio in Ni-Mn-Cu Cast Iron
Authors: Janus A. , Kurzawa A. 
Published: July 2013

Abstract
Determined was quantitative effect of nickel equivalent value on austenite decomposition degree during cooling-down castings of Ni-Mn- Cu cast iron. Chemical composition of the alloy was 1.8 to 5.0 % C, 1.3 to 3.0 % Si, 3.1 to 7.7 % Ni, 0.4 to 6.3 % Mn, 0.1 to 4.9 % Cu, 0.14 to 0.16 % P and 0.03 to 0.04 % S. Analysed were castings with representative wall thickness 10, 15 and 20 mm. Scope of the examination comprised chemical analysis (including WDS), microscopic observations (optical and scanning microscopy, image analyser), as well as Brinell hardness and HV microhardness measurements of structural components.
Geometry of Remeltings and Efficiency of the Surface Remelting Process Applied to Cobalt Alloy Castings
Authors: Mróz M. , Orłowicz W. , Tupaj M. 
Published: July 2013

Abstract
The paper summarises results of measurements of remelting area geometry, thermal efficiency and melting efficiency characterising the surface remelting process applied to castings of MAR-M-509 cobalt alloy. The remelting process was carried out with the use of GTAW (Gas Tungsten Arc Welding) method in protective atmosphere of helium, at the electric current intensity in the range from 100 A to 300 A, and the electric arc scanning velocity vs in the range from 200 mm/min to 800 mm/min. The effect of current intensity and electric arc scanning velocity on geometrical parameters of remeltings, thermal efficiency, and melting efficiency characterising the remelting process has been determined.
Effect of Salinity Stress on Yield, Component Characters and Nutrient Compositions in Rapeseed (Brassica napus L.) Genotypes
Authors: Valiollah Rameeh 
Published: July 2013

Abstract Crops growing in salt-affected soils may suffer from physiological drought stress, ion toxicity, and mineral deficiency which then lead to reduced growth and productivity. Eight rapeseed genotypes were evaluated at control and two salinity levels of irrigation, i.e. ECe=0 dS m-1 (control), 6 and 12 dS m-1. A factorial experiment based on completely randomized design with 4 replications was considered for evaluation of 24 treatments. Significant mean square of the salinity levels and genotypes were exhibited for 1000-seed weight, pod length, seed yield, Mg, K and Cl, indicating significant differences of genotypes for the traits at three salinity levels. Pods per plant and Mg had lowest variations among the genotypes at the high salinity levels. Hyola401, LRT1 and KRN1 with seed yield of 3.09, 2.78 and 2.30 g/plot, respectively were considered as salt tolerant genotypes. Stress (12dsm-1 ) to control ratio (S/C) which is indicating of salinity tolerance was high for seed yield of DSM12 and Hyola401.Significant positive correlation of seed yield with K and Cl, indicated that these shoot ions can be considered as good indicators for seed yield improving at saline environment.
Physicochemical Parameters of Probiotic Yoghurt with Bioactive Natural Products from Sea Buckthorn
Authors: Tifrea Anca , Tiţa Ovidiu , Máthé Endre , Ketney Otto 
Published: July 2013

Abstract
Probiotic dairy products are part of functional foods, which are made from fermented milk selected from a culture or a concentrate of bacteria that improve the microbial balance in the gut. These products have positive and beneficial influence on health and integrity of the human body. In the present study regarding the fortification with oil and pulp of sea buckthorn, was to obtained product similar to the conventional yoghurt, consistency and texture aimed at reducing heat treatments and stages technology in order to preserve nutritional quality. This research focused on optimizing the technology for obtaining yoghurt and selecting the best options regarding the addition of sea buckthorn pulp or oil, based on the following parameters : acidity, pH and lactic acid. At the same time we aimed to obtain probiotic yoghurt ,to make comparative studies on major parameters and to select the optimal probiotic yoghurt with sea bucktorn that give a good stabilization.
Modulation of rabbit muscle sarcoplasmic reticulum Ca2+-ATPase activity by novel quercetin derivatives
Authors: Blaškovič Dušan , Žižková Petronela , Držík Filip , Viskupičová Jana , Veverka Miroslav , Horáková Ľubica 
Published: July 2013

Abstract
Sarcoplasmic reticulum Ca2+-ATPase (SERCA) is the pump crucial for calcium homeostasis and its impairment results in pathologies such as myopathy, heart failure or diabetes. Modulation of SERCA activity may represent an approach to the therapy of diseases with SERCA impairment involvment. Quercetin is flavonoid known to modulate SERCA activity. We examined the effect of nine novel quercetin derivatives on the activity of the pump. We found that 5-morpholinohydroxypoxyquercetin, di(prenylferuoyl)quercetin, di(diacetylcaffeoyl)-mono-(monoacetylcaffeoyl)quercetin and monoacetylferuloylquercetin stimulated the activity of SERCA. On the contrary, monochloropivaloylquercetin, tri(chloropivaloyl)quercetin, pentaacetylquercetin, tri(trimethylgalloyl)quercetin and diquercetin inhibited the activity of the pump. To identify compounds with a potential to protect SERCA against free radicals, we assessed the free radical scavenging activity of quercetin derivatives. We also related lipophilicity, an index of the ability to incorporate into the membrane of sarcoplasmic reticulum, to the modulatury effect of quercetin derivatives on SERCA activity. In addition to its ability to stimulate SERCA, di(prenylferuloyl)quercetin showed excellent radical scavenging activity.
Efficacy of quercetin derivatives in prevention of ulcerative colitis in rats
Authors: Sotnikova Ruzena , Nosalova Viera , Navarova Jana 
Published: July 2013

Abstract
Reactive oxygen species has been implicated to contribute significantly to tissue injury associated with ulcerative colitis. Thus compounds with antioxidant properties could be potential therapeutic agents in this disease. Flavonoid compounds are known to possess antioxidative and antiinflammatory properties. Two derivatives of the flavonoid quercetin (Q), chloronaphthoquinone quercetin (CNC) and monochloropivaloyl quercetin (MCP), showed improved antioxidant properties and moreover, they efficiently inhibited aldose reductase activity in vitro. The aim of the work was to test the potential efficacy of quercetin and these synthetic derivatives in vivo in prevention of intestinal inflammation during ulcerative colitis in rats. Colitis was induced by intracolonic administration of acetic acid (4% solution). The control group received the same volume of saline. The vehicle dimethyl sulfoxide (DMSO) and the drugs Q, CNC or MCP were administered orally two hours and then one hour before the acetic acid or saline instillation. After 48 hours, the animals were sacrificed and the colon was weighed, measured and scored for visible damage. Acetic acid triggered an intense inflammatory response of the colon, characterised by haemorrhage, ulceration and bowel wall thickening. From the drugs tested, only CNC (2 × 50 mg/kg) effectively depressed inflammatory damage of the colon. The mechanism of this beneficial effect remains to be elucidated.
The Occurrence of the Viruses in Tulip Crops in Poland
Authors: Sochacki Dariusz 
Published: July 2013

Abstract
The viruses infecting tulips have a big influence on the yield and the quality of bulbs and forced flowers. Commercial bulb production is based on clonal propagation, which leads to the accumulation of viruses. Among 22 viruses occurring in tulips, the most common and the most dangerous are Tulip breaking virus, TBV; Tobacco necrosis virus, TNV; Lily symptomless virus, LSV; Cucumber mosaic virus, CMV and Tobacco rattle virus, TRV. The aim of the research was to check which viruses occur most often on Polish tulip plantations. The research was done on two tulip (Tulipa L.) cultivars ‘Strong Gold’ and ‘Leen van der Mark’ grown at 3 farms situated in different parts of Poland (Warsaw Region, Pomerania and Podlasie) during 2006-2007, and then at 2 farms located in Warsaw Region during 2008-2011. Five of the most important viruses infecting tulips (TBV, TNV, LSV, CMV, and TRV) were detected by double antibody sandwich enzyme-linked immunosorbent assay (DAS-ELISA) in leaves and in bulbs during the period 2006-2010. In the last year of the research two different strains of TRV were detected (TRV-J and TRV-F) and Tulip virus X (TVX) as well. Search for viruses showed that most often TBV virus was detected both in the leaves and the bulbs regardless of the year and plantations. Yellow flowering cultivar ‘Strong Gold’ was infected by viruses more often than in bi-coloured (with red) ‘Leen van der Mark’, because of the difficulties with effective roguing of infected plants due to inconspicuous symptoms of virus infections on yellow coloured flowers. Other viruses were detected sporadically, however increasing occurrence of LSV and TRV was noticed from year to year. In 2011, TVX virus was detected in a few plants of ‘Strong Gold’ and it was the first case of detection of this virus in tulip in Poland.
Detection of Narcissus Latent Virus Isolates Using One-Step Rt-Pcr Assay
Authors: Berniak Hanna , Komorowska Beata , Sochacki Dariusz 
Published: July 2013

Abstract
A one-step RT-PCR procedure was developed for specific detection of Narcissus latent virus (NLV) isolates. Following alignment of RNA sequences of three NLV isolates, the conserved sequence fragments were identified in viral polyprotein gene and 3’UTR region. Based on those fragments, a forward NLs1 and two reverse: NLa1 and NLSCPR2 primers were designed. Primer pairs NLs1-NLa1 and NLs1- NLSCPR2 proved to be effective in amplification of a 669 bp and 1295 bp products, respectively. Sequence analysis of amplified products confirmed their specificity.
Estimation of Interstock and Intermediate Stock Usefulness for Summer Pear Cvs. Budded on Two Rootstocks
Authors: Sosna Ireneusz , Kortylewska Daria 
Published: July 2013

Abstract
In order to increase the profitability of pear production, a greater density of weak growing trees per area unit should be planted. In Poland, the most frequently used pear dwarfing rootstocks are quince clones. The main disadvantage of them is a physiological incompatibility with some cultivars. The aim of this study was to evaluate the effect of the rootstock, interstock, and intermediate stock on growth and productivity of two summer pear cultivars, which are not compatible with the quince rootstock. Twoyear- old pear trees of ‘Radana’ and ‘Clapp’s Favourite’ cvs of different compositions were planted in the spring 2006. The following combinations were evaluated: ‘Radana’ and ‘Clapp’s Favourite’ on Caucasian pear seedlings, ‘Radana’ and ‘Clapp’s Favourite’ on quince SI with an intermediate stem piece of ’Doyenne du Comice’ and ‘Radana’ on Caucasian pear with ‘Pyrodwarf’ interstock. Up to the 6th year after planting, trees of ‘Radana’ grafted on Caucasian pear seedlings and on quince with intermediate stock yielded better than ‘Radana’ trees composed of Caucasian pear seedling and ‘Pyrodwarf’ interstock. ‘Clapp’s Favourite’ in all combinations had significantly heavier fruits. The highest crop efficiency index had ‘Radana’ on quince with ’Doyenne du Comice’ intermediate stock.
Assessment of Genetic Diversity in Cultivated Tomato (Solanum Lycopersicum L.) Genotypes Using Rapd Primers
Authors: Sharifova Saida , Mehdiyeva Sabina , Theodorikas Konstantinos , Roubos Konstantinos 
Published: July 2013

Abstract
Random Amplified Polymorphic DNA (RAPD) analysis was carried out on 19 Azerbaijan tomato genotypes, both cultivars and local populations. A total of 26 amplified products were revealed by 6 primers. The genetic similarity among evaluated genotypes ranged from 0.188 to 1.000. The lowest similarity was observed between cultivars ‘Azerbaijan’ and ‘Shakar’ (0.188), while the highest between ‘Elnur’ and ‘Garatag’ (1.000). The Unweighted Pair Group Method with Arithmetic Mean (UPGMA) cluster analysis based on Jaccard’s similarity coefficient divided genotypes into four main groups. The first group was the largest and consisted of 12 genotypes, while the fourth group was the smallest consisted of 1 genotype only. The most polymorphic primer was OPB-18 that presented a genetic diversity index of 0.823, while the least informative was primer OPG-17 with an index of 0.349. The average genetic diversity calculated from RAPD data was 0.665.
Impact of river current on the uniformity of littoral communities of Rotifera
Authors: Ejsmont-Karabin Jolanta , Zieliński Piotr 
Published: July 2013

AbstractStudies were carried out in September 2007 at a set of stations called RIVERS located on two tributaries of the Narew River, and six stations on the tributaries of the Supraśl River. Concurrently, rotifers were sampled at nine stations of the River Rudnia (called RUDNIA). The aim of the research was the verification of the hypothesis on the uniforming effect of the river drift on rotifer communities inhabiting aquatic vegetation. The total numbers of all monogonont species inhabiting aquatic vegetation of RUDNIA and RIVERS were 83 and 107, respectively. The percentage similarity of rotifer communities from aquatic vegetation and river current at the same stations was relatively low and only slightly higher in RIVERS (21.7%) than RUDNIA (17.1%), which suggests that species composition of communities of epiphytic rotifer fauna has a rather low impact on species structure of rotifer communities in water drift. The set of individuals of different species carried with the water current was random and various at different stations. Although the percentage similarity of rotifer communities in the river drift calculated for all possible pairs of the stations was relatively lower in RIVERS than in RUDNIA, it was not reflected in the similarity of epiphytic rotifer communities, which were similar in both sets of stations. Thus, the hypothesis cannot be confirmed by the results of this research.
Summer phytoplankton in selected lakes of the East Suwałki Lakeland in relation to the chemical water parameters
Authors: Grabowska Magdalena , Górniak Andrzej , Krawczuk Małgorzata 
Published: July 2013

AbstractThe study covered a complex of 16 lakes of the East Suwałki Lakeland, distinguished by high differentiation of morphometric parameters determining their polymictic or dimictic character. In half of the lakes studied, the occurrence of summer water thermal stratification was observed. It strongly influenced the vertical qualitative and quantitative diversification of phytoplankton. The majority of the lakes studied were classified as eutrophic waters. Only lakes Szelment Wielki and Pejcze had the Carlson chlorophyll index at the boundary of mesoeutrophy. In the case of the majority of the lakes, the concordance of all the trophy indices was recorded. In 6 mesoeutrophic lakes, the character of water was only suggested by phytoplankton parameters
Optimization of Flood Protection by Semi-Natural Means and Retention in the Catchment Area: A Case Study of Litavka River (Czech Republic)
Authors: Roub Radek , Novák Pavel , Hejduk Tomáš 
Published: July 2013

Abstract
Of all natural disasters, floods represent the most serious threat to the territory of the Czech Republic. This is given by the situation of the Czech Republic at the continental as well as the worldwide scale. At present, the design of anti-flood measures is mostly based on technical measures, without considering improvements in the hydromorphological status according to the Framework Directive on Water Management and without considering the natural transformation of flood discharge in the alluvial plains of water courses. This report presents a design for the optimization of anti-flood measures in the pilot catchment of the Litavka River, in which we propose particular measures for the catchment for its entire surface while providing a good hydromorphological status. We also wanted to quantify the proposed measures leading to the increased retention and accumulation capacities of the catchment area.
Location Matters! Exploring Brownfields Regeneration in a Spatial Context (A Case Study of the South Moravian Region, Czech Republic)
Authors: Frantál Bohumil , Kunc Josef , Nováková Eva , Klusáček Petr , Martinát Stanislav , Osman Robert 
Published: July 2013

Abstract
In this paper the authors attempt to answer the question of which location and site-specific factors have a decisive influence on the successful regeneration of brownfields. Using data from the South Moravian Region (Czech Republic), we analyze the spatial and functional distribution of brownfields, and test the correlation between the development potential of municipalities and the distribution of the brownfields that have already been regenerated. We then compare the structure and characteristics of existing and regenerated brownfields to identify significant drivers and barriers in the regeneration process. The findings indicate that regenerated brownfields are more likely located in municipalities with a higher local development potential (represented by the rate of local business activities, spatial peripherality - proximity to the regional centre and the main road network, and the quality of local infrastructure). It is also demonstrated that the large size of brownfields, their previous industrial use and the existence of contamination are not determinative barriers for regeneration if the brownfields are located in attractive areas and their ownership relations are not complicated.
Determination of Pressure Drop in Horizontal Pipes for Air – Water Two Phase Flow
Authors: Filip Alina 
Published: July 2013

Abstract
The gas-liquid two-phase flow is characterized by continuous and local change of surface separation of phases and by their mutual interactions. Due to the instability of the flow, heat transfer and mass, a precise analytical approach is difficult to achieve. Despite these difficulties, efforts are underway to progress from the more frequent empirical studies to reliable analytical models. This requires an accurate research of the processes involved in the two phase flow and how they interact with one another. This paper aims to determine the pressure drop for a two-phase flow in a horizontal pipe of a heating plant. The author compares the results obtained by numerical simulation with existing results in the domain. The mixture is air-water, at an environmental temperature of 25°C.