bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical factors associated with day‐to‐day peak pain severity in individuals with chronic migraine: A cohort study using daily prospective diary data
Authors: Vives‐Mestres Marina , Casanova Amparo , Silberstein Stephen D. , Hershey Andrew D. , Orr Serena L. 
Published: June 2024

AbstractObjectiveTo describe the association between day‐to‐day peak pain severity and clinical factors in individuals with chronic migraine (CM).BackgroundLittle is known about how clinical factors relate to day‐to‐day pain severity in individuals with CM.MethodsAdults with CM were enrolled into this observational prospective cohort study that collected daily data about headache, associated symptoms, and lifestyle factors using a digital health platform (N1‐Headache™) for 90 days. “Migraine days” were defined as days in which a headache occurred that had features described by the International Classification of Headache Disorders criteria. On these days, peak pain severity was recorded on a 4‐point scale; on non‐headache days peak pain severity was imputed as “0/none”. The associations between peak pain severity and 12 clinical factors were modeled and adjusted for sex, age, daily headache, presence of menstrual bleeding, day of the week, and disability. All numerical and Likert scale variables were standardized prior to analysis.ResultsData were available for 392 participants (35,280 tracked days). The sample was predominantly female (90.6%), with a mean (standard deviation) age of 39.9 (12.8) years. In the final multivariable model with random intercept and slopes, higher than typical self‐reported levels of standardized stress (odds ratio [OR] 1.07, 95% confidence interval [CI] 1.04–1.11), standardized irritability (OR 1.05, 95% CI 1.02–1.08), standardized sadness (OR 1.05, 95% CI 1.02–1.07), fatigue (OR 1.25, 95% CI 1.15–1.36), eyestrain (OR 1.38, 95% CI 1.26–1.52), neck pain (OR 1.94, 95% CI 1.76–2.13), skin sensitivity (OR 1.61, 95% CI 1.44–1.80), and dehydration (OR 1.29, 95% CI 1.18–1.42) were associated with higher reported peak pain severity levels, while standardized sleep quality (OR 0.96, 95% CI 0.93–0.99) and standardized waking feeling refreshed (OR 0.84, 95% CI 0.81–0.88) were associated with lower reported peak pain severity levels. The inclusion of a random intercept and random slopes improved upon more parsimonious models and illustrated large differences in individuals’ reporting of peak severity according to the levels of the associated clinical factors.ConclusionOur data showed that the experience of CM, from a pain severity perspective, is complex, related to multiple clinical variables, and highly individualized. These results suggest that future work should aim to study a personalized approach to both medical and behavioral interventions for CM based on which clinical factors relate to the individual's experience of pain severity.
Not their fault: Mental health characteristics of parents with migraine and the migraine status of their children
Authors: Marzouk Maya A. , Buse Dawn C. , Karvounides Dina , Powers Scott W. , Seng Elizabeth K. 
Published: June 2024

Plain Language SummaryIn the past, research indicated that a parent's mental health symptoms may impact their child's migraine status; however, these studies do not usually hold constant whether the parents themselves have migraine. This study provided new data suggesting that when parents have migraine, the connection between parents' mental health symptoms and their child's migraine status may be less pronounced. Future studies investigating the heritability of migraine and its related mental health conditions may consider this approach when recruiting study participants.
A review of thermal shock behavior of ceramics: Fundamental theory, experimental methods, and outlooks
Authors: Meng Qiaoyu , Zhang Keqiang , He Rujie , Qu Zhaoliang 
Published: June 2024

AbstractThe thermal shock resistance of ceramics is a key factor for determining the durability of ceramic components under transient thermal conditions and is also one of the key factors for evaluating the stability of ceramics under extreme thermal conditions. After rapid heating or cooling, the surface and internal thermal stress mismatches of ceramics can cause severe thermal damage. Two main types of ceramic thermal shock exist: rapid cooling and rapid heating thermal shock. This article presents a broad understanding and insight into fundamental theory and experimental methods for ceramic thermal shock testing. The experimental equipment and procedures, test result evaluation, and material characterization of ceramic thermal shock are summarized. Moreover, outlooks and perspectives are discussed for testing and characterizing ceramic thermal shock resistance. This review will be helpful to researchers performing studies in the relevant fields of ceramics.
Early childhood executive control modulates negative affectivity's role in increasing adolescent body mass index trajectories
Authors: Tomaso Cara C. , James Tiffany D. , Brock Rebecca L. , Yaroch Amy L. , Hill Jennie L. , Huang Terry T. , Nelson Jennifer M. , Mason W. Alex , Espy Kimberly A. , Nelson Timothy D. 
Published: June 2024

SummaryBackgroundExecutive control and temperament have been associated with pediatric obesity. However, interactions between these constructs in relation to future weight outcomes have not been investigated.ObjectiveThis longitudinal study examined early childhood executive control, early temperament (negative affectivity and surgency), and their interactions as predictors of adolescent BMI trajectories.MethodsAt age 5.25, children (N = 229) completed executive control tasks, and parents completed the Child Behavior Questionnaire to assess temperament. BMI was calculated annually between ages 14–17.ResultsGreater early negative affectivity predicted more positive BMI growth. Although early childhood executive control was not associated with BMI growth, greater negative affectivity predicted greater BMI escalation at average and below average executive control abilities.ConclusionsFor children without robust executive control abilities early in development, negative affectivity may be a risk factor for accelerated adolescent BMI growth. Targeted assessment of early risk factors may be useful for childhood obesity prevention efforts.
Chromium‐substituted bismuth titanate–niobate exhibiting superior piezoelectric performance for high‐temperature applications
Authors: Wang Qian , Liang En‐Meng , Wang Chun‐Ming 
Published: June 2024

AbstractHigh‐temperature piezoelectric ceramics with excellent piezoelectric properties are key materials for high‐temperature piezoelectric devices. In this context, bismuth titanate–niobate (Bi3TiNbO9) is one of the most promising candidates, owing to its high Curie temperature (TC) > 900°C. However, the relatively low piezoelectric response of prototype Bi3TiNbO9 does not satisfy the requirements of high‐precision and high‐sensitivity applications. Herein, chromium‐substituted Bi3TiNbO9 with a nominal composition, Bi3Ti1−xCrxNbO9 (BTN‐100xCr), was prepared using the solid‐state reaction method. Raman spectroscopy and X‐ray diffraction refinements revealed structural distortions induced by the substitution of chromium. Piezo‐response force microscopy and ferroelectric hysteresis loops showed facile polarization reversal and domain wall movement in chromium‐substituted Bi3TiNbO9. The resultant structural distortion and domain wall movement served as intrinsic and extrinsic contributions to the enhancement of the piezoelectric properties, respectively. Consequently, BTN‐1.5Cr exhibits a high piezoelectric constant (d33) of 17.7 pC/N, which is four times that of Bi3TiNbO9 (4.2 pC/N), a high TC of 908°C, and an excellent thermal stability of piezoelectric and electromechanical coupling properties up to 500°C. These results indicate that chromium substitution enhances the high‐temperature piezoelectric properties of Bi3TiNbO9, and chromium‐substituted Bi3TiNbO9 is a promising candidate for high‐temperature piezoelectric applications.
Examining socio‐ecological transitions and new human–wildlife relations in farming landscapes of the Nepal Himalaya
Authors: Khatri Dil , Paudel Dinesh , Poudyal Bishnu Hari , Khatri Sanjaya , Poudel Dilli P. , Marquardt Kristina 
Published: June 2024

AbstractWildlife invasion into farmlands is emerging as an acute problem in the Himalayas, threatening farm‐based livelihood systems of smallholder rural communities. The problem is severe in the areas where successful forest restoration has been achieved by community forestry programmes alongside massive outmigration. Such evolving dynamics have created new conceptual and empirical discourses on conservation, nature‐society relations and human‐wildlife interactions, as some wild animals have become pests for farming communities. Consequently, the historical co‐existence and relationships between subsistence communities and local ecosystems have been destabilized. By mobilizing the concepts of forest transition and agrarian transition, we explore these new and emerging relationships between the growing wildlife problem and deteriorating people's livelihood by examining the nature, extent and drivers of the new human‐wildlife interactions and provide critical insights towards effectiveness of current policies and practical responses.
Effect of strain and enteric septicemia of catfish vaccine‐booster on production and processing traits of the Delta Select and Delta Control strains of channel catfish, Ictalurus punctatus
Authors: Bosworth Brian , Waldbieser Geoff , Wise Dave , Kumar Ganesh , Lourenco Daniela , Garcia Andre , Ott Brian , Torrans Les 
Published: June 2024

AbstractThe Delta Select channel catfish strain (DS) was developed by selection for increased growth and carcass yield. Progeny from DS and the Delta Control (DC) strain (a randomly bred strain from the same base population as DS) were compared in three trials. Trial 1: unvaccinated ~1‐year‐old fingerlings from each strain reared communally in 0.4‐ha ponds. Trial 2: vaccinated ~ 1‐year‐old fingerlings from each strain grown in separate replicated 0.4‐ha ponds and fish in about half the ponds were given an ESC vaccine‐booster at 13 months post‐hatch. Trial 3: same procedures as Trial 2, except fish were raised in replicate 0.04‐ha ponds with no vaccine‐booster. In Trial 1 DS were larger at stocking, larger at harvest, and had higher carcass yield than DC; in Trial 2 DS were larger at harvest, had better survival and higher production/ha than DC. Vaccine‐booster had no effect on fish growth or survival. DS and DC were not different for any traits in Trial 3. Although outcome varied among trials, the overall results indicated a vaccine booster did not affect growth or survival, DS strain fingerlings grew faster than DC fingerling, and DS had higher carcass yield than DC strain fish when reared communally.
Long‐term albumin improves the outcomes of patients with decompensated cirrhosis and diabetes mellitus: Post hoc analysis of the ANSWER trial
Authors: Pompili Enrico , Baldassarre Maurizio , Iannone Giulia , Tedesco Greta , Nardelli Silvia , Piano Salvatore , Alessandria Carlo , Neri Sergio , Foschi Francesco G. , Levantesi Fabio , Caraceni Paolo , Bernardi Mauro , Zaccherini Giacomo ,   for the ANSWER Study Investigators
Published: June 2024

AbstractType‐2 diabetes mellitus is a frequent comorbidity of cirrhosis independently associated with cirrhosis‐related complications and mortality. This post hoc analysis of the ANSWER trial database assessed the effects of long‐term human albumin (HA) administration on top of the standard medical treatment (SMT) on the clinical outcomes of a subgroup of 85 outpatients with liver cirrhosis, uncomplicated ascites and insulin‐treated diabetes mellitus type 2 (ITDM). Compared to patients in the SMT arm, the SMT + HA group showed a better overall survival (86% vs. 57%, p = .016) and lower incidence rates of paracenteses, overt hepatic encephalopathy, bacterial infections, renal dysfunction and electrolyte disorders. Hospital admissions did not differ between the two arms, but the number of days spent in hospital was lower in the SMT + HA group. In conclusion, in a subgroup of ITDM outpatients with decompensated cirrhosis and ascites, long‐term HA administration was associated with better survival and a lower incidence of cirrhosis‐related complications.
Mathematics Presentation Matters: How Superfluous Brackets and Higher‐order Operator Position in Mathematics Can Impact Arithmetic Performance
Authors: Egorova Alena , Ngo Vy , Liu Allison S. , Mahoney Molly , Moy Justine , Ottmar Erin 
Published: June 2024

AbstractPerceptual learning theory suggests that perceptual grouping in mathematical expressions can direct students' attention toward specific parts of problems, thus impacting their mathematical reasoning. Using in‐lab eye tracking and a sample of 85 undergraduates from a STEM‐focused university, we investigated how higher‐order operator position (HOO; i.e., multiplication/division operators and the presence of superfluous brackets impacted students' time to first fixation to the HOO, response time, and percent of correct responses). Students solved order‐of‐operations problems presented in six ways (3 HOO positions × presence of brackets). We found that HOO position and presence of superfluous brackets had separate and combined impacts on calculating arithmetic expressions. Superfluous brackets most influenced undergraduates' performance when higher‐order operators were located in the center of mathematical expressions. Implications for learning and future directions are discussed about observing eye movements and gaining insights into students' processes when solving arithmetic expressions.
Impact of anesthesia drugs on digestive motility measurements in humans: A systematic review
Authors: Renard Domitille , Clavier Thomas , Gourcerol Guillaume , Desprez Charlotte 
Published: June 2024

AbstractBackground and PurposeMeasurement of gastro‐intestinal motility is increasingly performed under general anesthesia during endoscopic or surgical procedures. The aim of the present study was to review the impact of different anesthetic agents on digestive motility measurements in humans.MethodsThis systematic review was performed using the Medline‐Pubmed and Web of Science databases. All articles published until October 2023 were screened by identification of key words. Studies were reviewed if patients had an assessment of digestive motility using conventional perfused manometry, high‐resolution manometry, electronic barostat or functional lumen impedance planimetry with the use of inhaled or intravenous anesthetic anesthetic agents (propofol, ketamine, halogens, nitrous oxide, opioids, and neuromuscular blockades).ResultsFour hundred and eighty‐eight unique citations were identified, of which 42 studies met the inclusion criteria and were included in the present review. The impact of anesthetics was mostly studied in patients who underwent esophageal manometry. There was a heterogeneity in both the dose and timing of administration of anesthetics among the studies. Remifentanil analgesia was the most studied anesthetic drug in the literature, showing a decrease in both distal latency and lower esophageal sphincter pressure after its administration, but the impact on Chicago classification was not studied. Inhaled anesthetics administration elicited a decrease in lower esophageal sphincter pressure, but contradictory findings were shown on esophageal motility following propofol or neuromuscular blocking agents administration.ConclusionStudies of the impact of anesthetics on digestive motility remain scarce in the literature, although some agents have been reported to profoundly affect gastro‐intestinal motility.
Pepper SUMO protease CaDeSI2 positively modulates the drought responses via deSUMOylation of clade A PP2C CaAITP1
Authors: Joo Hyunhee , Baek Woonhee , Lim Chae Woo , Lee Sung Chul 
Published: June 2024

Summary

Posttranslational modification of multiple ABA signaling components is an essential process for the adaptation and survival of plants under stress conditions. In our previous study, we established that the pepper group A PP2C protein CaAITP1, one of the core components of ABA signaling, undergoes ubiquitination mediated by the RING‐type E3 ligase CaAIRE1.

In this study, we discovered an additional form of regulation mediated via the SUMOylation of CaAITP1. Pepper plants subjected to drought stress were characterized by reductions in both the stability and SUMOylation of CaAITP1 protein.

Moreover, we identified a SUMO protease, Capsicum annuum DeSUMOylating Isopeptidase 2 (CaDeSI2), as a new interacting partner of CaAITP1. In vitro and in vivo analyses revealed that CaAITP1 is deSUMOylated by CaDeSI2. Silencing of CaDeSI2 in pepper plants led to drought‐hypersensitive and ABA‐hyposensitive phenotypes, whereas overexpression of CaDeSI2 in transgenic Arabidopsis plants resulted in the opposite phenotypes. Importantly, we found that the CaAITP1 protein was stabilized in response to the silencing of CaDeSI2, and CaDeSI2 and CaAITP1 co‐silenced pepper plants were characterized by drought‐tolerant phenotypes similar to those observed in CaAITP1‐silenced pepper.

Collectively, our findings indicate that CaDeSI2 reduces the stability of CaAITP1 via deSUMOylation, thereby positively regulating drought tolerance.
Leaf isotopes reveal tree diversity effects on the functional responses to the pan‐European 2018 summer drought
Authors: Jing Xin , Baum Christel , Castagneyrol Bastien , Eisenhauer Nico , Ferlian Olga , Gebauer Tobias , Hajek Peter , Jactel Hervé , Muys Bart , Nock Charles A. , Ponette Quentin , Rose Laura , Saurer Matthias , Scherer‐Lorenzen Michael , Verheyen Kris , Van Meerbeek Koenraad 
Published: June 2024

Summary

Recent droughts have strongly impacted forest ecosystems and are projected to increase in frequency, intensity, and duration in the future together with continued warming. While evidence suggests that tree diversity can regulate drought impacts in natural forests, few studies examine whether mixed tree plantations are more resistant to the impacts of severe droughts.

Using natural variations in leaf carbon (C) and nitrogen (N) isotopic ratios, that is δ13C and δ15N, as proxies for drought response, we analyzed the effects of tree species richness on the functional responses of tree plantations to the pan‐European 2018 summer drought in seven European tree diversity experiments.

We found that leaf δ13C decreased with increasing tree species richness, indicating less drought stress. This effect was not related to drought intensity, nor desiccation tolerance of the tree species. Leaf δ15N increased with drought intensity, indicating a shift toward more open N cycling as water availability diminishes. Additionally, drought intensity was observed to alter the influence of tree species richness on leaf δ15N from weakly negative under low drought intensity to weakly positive under high drought intensity.

Overall, our findings suggest that dual leaf isotope analysis helps understand the interaction between drought, nutrients, and species richness.
The effect of individualized ocular refraction customized spectacle lenses on myopia control in schoolchildren: A 1‐year randomised clinical trial
Authors: Lei Si , Wu Ye , Kou Ji , Chen Qian , Liu Longqian 
Published: June 2024

AbstractPurposeThe aim of this study was to investigate the effect of individualized ocular refraction customized (IORC) spectacle lenses with different actual amounts of peripheral myopic defocus (MD) on myopia control over 1 year. These lenses compensate for the original peripheral refraction via the free‐form surface on the back of the lens.MethodsThis 1‐year, double‐masked randomised clinical trial included 184 myopic schoolchildren aged 8–12 years. Participants were randomised to receive IORC lenses with high (IORC‐H group, +4.50 D), medium (IORC‐M group, +3.50 D) or low (IORC‐L group, +2.50 D) MD or single‐vision (SV) lenses. The spherical equivalent refractive error (SER) and axial length (AL) were measured at baseline and 6‐monthly intervals.ResultsAfter 1 year, the mean (SD) changes in SER were −0.18 (0.37), −0.36 (0.37), −0.52 (0.39) and −0.60 (0.42) D for the IORC‐H, IORC‐M, IORC‐L and SV groups, respectively. Compared with the SV group, the effects of slowing myopia progression were 70%, 40% and 13% for the IORC‐H (difference of 0.47 D, p < 0.001), IORC‐M (difference of 0.32 D, p = 0.001) and IORC‐L (difference of 0.15 D, p > 0.05) groups, respectively. The mean (SD) changes in AL were 0.12 (0.16), 0.23 (0.17), 0.29 (0.17) and 0.36 (0.17) mm for the IORC‐H, IORC‐M, IORC‐L and SV groups, respectively. The axial elongation was 67%, 36% and 19% lower in the IORC‐H (difference of 0.25 mm, p < 0.001), IORC‐M (difference of 0.15 mm, p < 0.001) and IORC‐L (difference of 0.10 mm, p = 0.04) groups, respectively, compared with the SV group. The IORC‐H group exhibited significantly less axial elongation than the IORC‐M and IORC‐L groups (p = 0.01 and p < 0.001, respectively).ConclusionCompared with the IORC‐M and IORC‐L lenses, the IORC‐H lens was found to have superior efficacy in inhibiting myopic progression and slowing eye growth in schoolchildren, with better myopia control efficacy in younger children.
Corporate tax, R&D and export decisions: Evidence from European firms
Authors: Bournakis Ioannis , Romero‐Jordán Desiderio 
Published: June 2024

AbstractThe paper presents a unified framework for analyzing the impact of corporate taxation on R&D and exporting, considering firm productivity heterogeneity and sunk costs. We empirically examine three hypotheses using data from 7819 European firms spanning 2001–2014. We propose that: (a) an increase in corporate tax reduces the likelihood of innovation, (b) an increase in corporate tax reduces the likelihood of exporting, and (c) firms that innovate are more likely to enter foreign markets. On average, a high Effective Average Tax Rate (EATR) lowers the probability of investing in R&D and exporting by 2.3% and 1.41%, respectively. For firms with low Total Factor Productivity (TFP), the adverse effect of taxation on R&D investment ranges from 3.71% in our baseline analysis to 12.9% in our sensitivity analysis. Interestingly, while EATR positively influences the export decisions of high‐TFP firms, a higher EATR can reduce the export probability by up to 25.5% for firms at the lower end of the TFP distribution. Our findings demonstrate a causal relationship between firm heterogeneity and their capacity to mitigate the distortions caused by higher taxes. From a policy perspective, our results suggest that fostering innovation is essential for firms aiming to expand into international markets.
When demography is (not) destiny: Exploring identity and issue cross‐pressures among Latino voters in the 2020 presidential election
Authors: Corral Álvaro J. , Leal David L. 
Published: June 2024

AbstractObjectiveScholars have struggled to understand Donald Trump's surprising levels of Latino support in two consecutive presidential elections. We test three hypotheses to better understand the strength and weakness of Trump, Biden, and both political parties.MethodsWe conduct bivariate and multivariate analyses of pre‐ and post‐election surveys to identify sources of support (beyond national origin differences) that explain how Trump improved his level of support among Latino voters to reach the low‐ to mid‐ 30 percent range.ResultsIntra‐Latino differences in ideology, identity (gender and religion), and immigration attitudes help explain Trump's relatively strong showing among Latinos in 2020.ConclusionWhile the nation's electorate is becoming more demographically diverse, many predictions associated with the notion of “demography as destiny” should be tempered given the political heterogeneity among Latino voters.