bluuebunny/crossref_metadata_2025_split huggingface dataset:
Apical Accumulation of the Sevenless Receptor Tyrosine Kinase During Drosophila Eye Development Is Promoted by the Small GTPase Rap1
Authors: Baril Caroline , Lefrançois Martin , Sahmi Malha , Knævelsrud Helene , Therrien Marc 
Published: June 2014

Abstract
The Ras/MAPK-signaling pathway plays pivotal roles during development of metazoans by controlling cell proliferation and cell differentiation elicited, in several instances, by receptor tyrosine kinases (RTKs). While the internal mechanism of RTK-driven Ras/MAPK signaling is well understood, far less is known regarding its interplay with other corequired signaling events involved in developmental decisions. In a genetic screen designed to identify new regulators of RTK/Ras/MAPK signaling during Drosophila eye development, we identified the small GTPase Rap1, PDZ-GEF, and Canoe as components contributing to Ras/MAPK-mediated R7 cell differentiation. Rap1 signaling has recently been found to participate in assembling cadherin-based adherens junctions in various fly epithelial tissues. Here, we show that Rap1 activity is required for the integrity of the apical domains of developing photoreceptor cells and that reduced Rap1 signaling hampers the apical accumulation of the Sevenless RTK in presumptive R7 cells. It thus appears that, in addition to its role in cell–cell adhesion, Rap1 signaling controls the partitioning of the epithelial cell membrane, which in turn influences signaling events that rely on apico-basal cell polarity.
Modernity and the Challenge of Pluralism: Some Indonesian Lessons
Authors: Hefner Robert W. 
Published: June 2014

In the tradition of Western social sciences to grow a sense of " hard " about the secularization : the removal of religion from public life ; religion is only a private matter of each person ; he did not have a significant social role .The idea of ​​secularization or the desecration of the Muslim reformer Indonesia has made Islam is not synonymous with social groups - political . Islam has been freed from political conflicts to be accepted by the wider Muslim community . Categories gentry , students , and abangan , Clifford Geertz used to distinguish religious orientation among Javanese Muslims , is no longer relevant to use . Gentry and abangans now been merged into the religious culture of the students . Now taking place what is called a " santrinisasi " or " Islamization " in Indonesia . It takes place in Indonesian society is becoming increasingly modern , where the middle class is getting stronger . Islam has become the culture of the middle class . Modernity hand with Islam . In Indonesia , Islam can also accommodate the challenges of plurality , which is the other side of modernity . Islam has contributed positively to the life of the nation-state of Indonesia.DOI: 10.15408/sdi.v2i4.819
Islamic Political Thought and Cultural Revival in Modern Indonesia
Authors: Syamsuddin M. Din 
Published: June 2014

Views of Islamic political thought, at least there are three currents of thought among Indonesian Muslim intellectuals; formalistic currents, currents substantivistik, and fundamentalist currents. One view of current formalistic, he said Islam is a universal religion and overall (total). He emphasized the power of God on earth and as the views of Islamic fundamentalism, the danger of "Westoxication" or "jahili modern society". For this group, Islam must be instituted in order to be a force for liberation in this world. This institutionalization will pave the way for the formation of modern society Qur'anis.DOI: 10.15408/sdi.v2i4.820
Islam dalam Oposisi Demokratis di Indonesia
Authors: Priyono AE 
Published: June 2014

This article is a review of the book "Democracy and Diffusion: Transnational Lesson Drawing among Indonesian Pro-Democracy Actors" by Uhlin unders (87 Lund Political Studies, Department of Political Science, Lund University, 1995).Anders Uhlin publication of a book which was originally a dissertation at the University of Lund, Sweden, is motivated by the noisy atmosphere of a critique of theories of political regime transitions. Uhlin himself considered that the transition theories suffer from a bias towards the view as if democracy is only relevant in any political environment, and because it always implies the need for democratization of the regime transformation. Broader issues concerning democratization of civil-society, which often does not imply a transition regime, tend to be ignored by the theories of transition. That's why he said, the transition to democracy should be analyzed in conjunction with developments in the wider community.DOI: 10.15408/sdi.v2i4.826
Masīrah al-Ḥajj wa Ta‘thīruhā ‘ala al-Taṭawwur al-Islāmī fī al-Qarnayn al-Tāsi‘ ‘Ashr wa al-‘Ishrīn fī Indūnīsīyā
Authors: Ibrahim Umar 
Published: June 2014

Pilgrimage in ritual practice is not only valuable but also political, economic, and pedagogical. That's because the Hajj is itself a grand conference attended by millions of people from various parts of the world with a background in economics, politics, social and cultural diversity. This grand congress often used for political interests by Muslim rulers so that this opportunity is most practical political forum to influence, shape and spread of certain patterns of thought to various other parts of the Muslim world. In the 18th century, every year thousands of pilgrims go to Mecca and came home with orthodox Islam which gradually able to shift mistisismedan syncretism previously more prominent in the history of Islamic thought in Indonesia as seen Kalisalak Rifa'i Ahmad (1786-1875). They were also instrumental in mobilizing the masses in the resistance against the invaders.DOI: 10.15408/sdi.v3i1.816
Politik Indonesia Tahun 1990-an: Kebangkitan Ideologi?
Authors: Mujani Saiful 
Published: June 2014

This article is a review of the book Politics in Indonesia : Democracy , Islam and the Ideology of Tolerance written by Douglas E. Ramage . This book is the result of research that lasted from 1990-1994 , a period characterized much political debate and move groups of Indonesia, including from Islamic groups . The problem is studied from this book is a discourse about Pancasila as interpreted by these groups with all the implications of the widespread national problem .According to Ramage , initially it looked Pancasila as an ideology that is not interesting , nothing more than a tool of legitimacy of the New Order power elite . But after carefully considered , as it turns out wrong impression . Pancasila has turned out to be an interesting and important discourse studied . Pancasila turned out to be above the interests of the power elite . He became a central discourse in Indonesian politics , involving a variety of groups and interests . The debate over the interpretation of Pancasila inevitableDOI: 10.15408/sdi.v3i1.817
The Tragedy Cimareme: The Resistance of Haji Hasan to the Colonial Power in 1919
Authors: Hajati Chusnul 
Published: June 2014

History records "Cimareme events" as one of the important events during the year 1919 in Indonesia. This event is the culmination of resistance Cimareme villagers, led by Haji Hasan, against the Dutch colonial government.The key drivers of this event is more economical interests. A year before the incident erupted, the Dutch colonial government set the rules for the purchase of paddy indigenous farmers. This step was taken to address food shortages due to crop failures and difficulties imports.Rules set by the government rice purchase is deemed unfair by Haji Hasan. The government requires that farmers in other regions to only sell them as two measures of rice per smell land, while farmers are required to sell their rice two times more than that number. Hajj Hasan questioned this rule, and determined not to sell rice to the government. This attitude then cause conflicts with local indigenous officials, and finally the Dutch colonial government took strong action through the raid.DOI: 10.15408/sdi.v3i2.807
Pulmonary function derangements in isolated or predominant mitral stenosis — Preoperative evaluation with clinicohemodynamic correlation
Authors: Parvathy Usha T. , Rajan Rajesh , Georgevich Faybushevich Alexander 
Published: June 2014

AbstractIntroductionIt is well known that mitral stenosis (MS) is complicated by pulmonary hypertension (PH) of varying degrees. The hemodynamic derangement is associated with structural changes in the pulmonary vessels and parenchyma and also functional derangements. This article analyzes the pulmonary function derangements in 25 patients with isolated/predominant mitral stenosis of varying severity.AimsThe aim of the study was to correlate the pulmonary function test (PFT) derangements (done by simple methods) with: a) patient demographics and clinical profile, b) severity of the mitral stenosis, and c) severity of pulmonary artery hypertension (PAH) and d) to evaluate its significance in preoperative assessment.Subjects and MethodsThis cross-sectional study was conducted in 25 patients with mitral stenosis who were selected for mitral valve (MV) surgery. The patients were evaluated for clinical class, echocardiographic severity of mitral stenosis and pulmonary hypertension, and with simple methods of assessment of pulmonary function with spirometry and blood gas analysis. The diagnosis and classification were made on standardized criteria. The associations and correlations of parameters, and the difference in groups of severity were analyzed statistically with Statistical Package for Social Sciences (SPSS), using nonparametric measures.ResultsThe spirometric parameters showed significant correlation with increasing New York Heart Association (NYHA) functional class (FC): forced vital capacity (FVC,r= −0.4*,p= 0.04), forced expiratory volume in one second (FEV1,r= −0.5*,p= 0.01), FEV1/FVC (r= −0.44*,p= 0.02), and with pulmonary venous congestion (PVC): FVC (r= −0.41*,p= 0.04) and FEV1 (r= −0.41*,p= 0.04). Cardiothoracic ratio (CTR) correlated only with FEV1 (r= −0.461*,p= 0.02) and peripheral saturation of oxygen (SPO2,r= −0.401*,p= 0.04). There was no linear correlation to duration of symptoms, mitral valve orifice area, or pulmonary hypertension, except for MV gradient with PCO2 (r= 0.594**,p= 0.002). The decreased oxygenation status correlated significantly with FC, CTR, PVC, and with deranged spirometry (r= 0.495*,p= 0.02).ConclusionsPFT derangements are seen in all grades of severity of MS and correlate well with the functional class, though no significant linear correlation with grades of severity of stenosis or pulmonary hypertension. Even the early or mild derangements in pulmonary function such as small airway obstruction in the less severe cases of normal or mild PH can be detected by simple and inexpensive methods when the conventional parameters are normal. The supplementary data from baseline arterial blood gas analysis is informative and relevant. This reclassified pulmonary function status might be prognostically predictive.
Successful reimplantation of the hypertrophied inferior mesenteric artery during an open abdominal aortic aneurysm repair
Authors: Kaczynski Jakub , Jaber Basel , Atherton Steve , Fligelstone Louis 
Published: June 2014

Abstract
Ischemic colitis is the most common form of an iatrogenic intestinal ischemia following an aortic surgery. It can be transient and self-limiting but, when severe, is associated with mortality even as high as 80%. Careful preoperative assessment can help to anticipate the need for the inferior mesenteric artery (IMA) reimplantation. Some patients lack the sufficient collateral blood supply to the colon and can benefit from the IMA reimplantation, which not only reduces the risk of postoperative colonic necrosis but also can be lifesaving. We report a case of a successful reimplantation of the IMA based on the careful preoperative planning. If unrecognized, this undoubtedly would lead to postoperative colonic ischemia. Therefore, we feel it is important to share our experience regarding the successful management of the presented case.
Successful thrombolysis using recombinant tissue plasminogen activator in cases of severe pulmonary embolism with mobile thrombi in the right atrium
Authors: Şatiroğlu Ömer , Durakoğlugil Murtaza Emre , Uğurlu Yavuz , Şahin İsmail , Doğan Sitki , Ergül Elif , Karadağ Zakir , Bostan Mehmet 
Published: June 2014

Abstract
Hereby, we report two cases of acute pulmonary embolism with concomitant right-sided thrombus, which were successfully treated using recombinant tissue plasminogen activator (rtPA). These patients had life-threatening acute right ventricular failure, which dramatically improved within hours following thrombolysis. These cases emphasize the clinical utility of rtPA for the treatment of life-threatening pulmonary embolism.
Retrieval of embolized tip of port catheter from branch of right pulmonary artery using a macro snare catheter
Authors: Bostan Mehmet , Durakoğlugil Murtaza Emre , Şatiroğlu Ömer , Erdivanli Başar , Tufan Gülnihal 
Published: June 2014

Abstract
Rupture of the silicon port catheter is a relatively rare complication. Ruptured part usually embolizes; therefore, removal of foreign body may be difficult. These ports usually migrate to right-sided chambers, main pulmonary arteries, and pulmonary subbranches. Different devices such as snares, basket catheters, and ablation catheters are utilized for retrieval. Hereby, we report successful extraction of an embolized 10-cm tip of a vascular access port using a macro snare catheter.
High Pressure and Temperature Elasticity and EOS for Actinide Metals from First-Principles Simulations
Authors: Wu Christine J. , Söderlind Per 
Published: June 2014

ABSTRACTDensity-functional theory (DFT) simulations are applied to obtain elastic, strength, and EOS properties of actinide metals under extreme conditions. In this presentation, we will show our recent study on temperature effects of the properties of solids of actinide metals. For example of low temperature uranium (U) solids, elastic constants are calculated directly from the DFT total energy for the ground-state phase in a wide pressure range. For higher temperature U solids, we are applying a recent scheme to calculate temperature-dependent phonon dispersions through the self-consistent ab initio lattice dynamics (SCAILD) technique. This scheme is particular important for the higher temperature phases that the elasticity cannot be analogously obtained because of its mechanical instability at lower temperatures. From these SCAILD phonon dispersions we then extract the elastic constants from the slopes approaching the Γ point. In addition, the phonon density of states of U obtained from SCAILD/DFT calculations have been used to parameterize a double Debye model for its ion-thermal free energy. We will discuss the ramification of this new Debye model on our development of multi-phase uranium EOS.
A DFT Study of B, N and BN Doped Graphene
Authors: Rani Pooja , Jindal V. K. 
Published: June 2014

ABSTRACTWe have made a density functional study of the structural and electronic properties of B or N (individual) doped and BN co-doped graphene. The effect of doping has been studied by incorporating the doping concentration amount varying from 2% (one atom of the dopant in 50 host atoms) to 12 % atomic concentration in case of individual doping and from 4% (2 atoms of the dopant in 50 host atoms) to 24 % in case of co-doping, at the same time, altering different doping sites for the same concentration of substitutional doping. We made use of VASP (Vienna Ab-Initio Simulation Package) software based on density functional theory to perform all calculations. While the resulting geometries do not show much of distortion on doping, the electronic properties show a transition from semimetal to semiconductor with increasing number of dopants. The study shows that the BN doping introduces the band gap at the Fermi level unlike individual B and N doping which causes the shifting of Fermi level above or below the Dirac point. It is observed that not only concentration but position of B and N atoms in the hetero-structure also affects the value of band gap introduced.
The Challenging World of Cytopenias: Distinguishing Myelodysplastic Syndromes From Other Disorders of Marrow Failure
Authors: DeZern Amy E. , Sekeres Mikkael A. 
Published: June 2014

AbstractOver the past decade, our understanding of bone marrow failure has advanced considerably. Marrow failure encompasses multiple overlapping diseases, and there is increasing availability of diagnostic tools to distinguish among the subtypes. Identification of genetic alterations that underlie marrow failure has also greatly expanded, especially for myelodysplastic syndromes. Molecular markers are increasingly used to guide the management of myelodysplasia and may distinguish this diagnosis from other marrow failure disorders. This review summarizes the current state of distinguishing among causes of marrow failure and discusses the potential uses of multiple diagnostic and prognostic indicators in the management of myelodysplastic syndromes and other bone marrow failure disorders.
Dynamic Reservoir Characterization with PTA: Clastic Environments
Authors: Rodolfo J. , Phillips G. , BinAkresh Saud A 
Published: June 2014

Abstract
This paper presents key aspects of a systematic effort for using pressure transient analysis (PTA) as an important building block of full-field reservoir characterization of clastic oil fields in Saudi Arabia. The well-test data for PTA is an important step on the ladder of any integrated reservoir study, aiming at reconciling differences between the static and dynamic models. In this work, a large number of well tests have been analyzed and integrated with other field data. This work highlights the importance of PTA results in refining reservoir descriptions, including permeability modeling and fault characterization in clastic fields. The review of the PTA results, along with other reservoir characterization data of clastic oil fields, has significantly broadened dynamic understanding under a synergistic and multidisciplinary approach.
The subject fields are part of a major fluvial deltaic deposit trend, consisting of stacked oil bearing sandstone reservoirs with inter-bedded shales where the main reservoirs are primarily composed of coarse to fine grained sandstones with thin shale and siltstone intercalations with some lateral barriers (faulting) as captured by seismic data. For the purpose of this study, the fields have been subdivided into several assessment areas with representative transient data to capture the reservoir geology and dynamics. Pressure buildup tests from a number of multi-well groups, generally conducted during single-phase flow (before water breakthrough), have been analyzed by analytical and numerical methods. The analyses of wireline and large, real-time Intelligent Field data have provided key dynamic well parameters, such as permeability-thickness product (kh), productivity index and anisotropy ratio (kv/kh), which are critical input parameters to permeability modeling and history-matching processes. PTA results have also helped in refining reservoir descriptions with events as identifying areas of mobility contrasts, shale body and lateral flow boundaries. Examples of the observed major geological features in the studied fields will be presented.
Application of MFO Injections Procedure for MSF Packers Integrity Diagnostic
Authors: Nugraha Ikhsan , Said Rifat 
Published: June 2014

Abstract
In recent years, multistage fracturing completion has been adopted by many operators across the globe as a primary means to maximize reservoir contact. To succeed, this completion strategy must be complemented with good understanding on petrophysical and geomechanical properties of the reservoir; which resulted in a better understanding of fracture orientation and decisions on open hole length, number of fracturing stages, packers and frac ports placement.
When dealing with a low permeability environment, for a specific open hole length, it is almost certain that increasing the number of fracturing stages will potentially give the highest productivity. Subsequently, this will also potentially increase the chance of having packer integrity issues due to the shorter distance between the frac port and packers.
Currently, the most common practice to evaluate packer integrity is done on-site, by comparing pressure response at a constant injection rate before and after opening a frac port, in addition to observing breakdown and closure pressure for each compartment. In the event of similar pressure response on both sides, it may be an indication of communication. Consequently, relying only on this injection exclusively is not sufficient because the leak-off profiles may suggest otherwise and could lead to drawing the wrong conclusions.
This paper describes a new enhancement of the mini fall off (MFO) injections procedure, which can be used to confirm multistage fracturing packer's integrity on-site. The procedure consists of performing injection with similar small volume and rate before and after opening the frac port, overlaying pressure responses, pressure decline analysis, as well as comparing pressure derivative for both injections. This technique has been successfully tested on-site where one out of seven stages planned were identified to have communication and has helped in the decision making process to skip the stage and avoid stimulating the same compartment again.
Characterization of Crude Oil of Upper Assam Field for Flow Assurance
Authors: Jha Nilesh Kumar , Jamal Mohammad Shahid , Singh Diwakar , Prasad Uma Shanker 
Published: June 2014

Abstract
Crude oil characterization is important prior to development of complex network of surface and subsurface facilities for oil and gas production. Fluid behavior change in multiple set of conditions could cause problems related to fluid flow, solid deposition, wax formation and fluid transportation. This change could pose additional risk with tough terrains and challenging environments and it could jeopardize the project cost economics too.
In this paper laboratory result of crude oil evaluation of Upper Assam Field, India is presented. The purpose of the present work was to examine the behavior of produced fluid with highlighting issues which could impact on safety, integrity, production capacity and operational support for the asset throughout project lifecycle. Strategies can then be developed to resolve those issues. Detailed carbon profile of crude oil and wax content, distribution of molecular weight were determined through simulated distillation (SIMDIS) using Perkin Elmer Gas Chromatograph hardware and software. Physical characterization such as density, pour point, water content, bound sand and water, KUOP, wax content was done using ASTM methods. Boiling point profile generated from the experiments was used to find crude oil type. Saturates, aromatics, resins and asphaltene (SARA) analysis was done using standard method to find asphaltene deposition potential. Normal and non-normal paraffinic content of wax is calculated using the "Wax Profiling" software from ControlChrom to find wax predominating characteristics. Tulsa University "WAX" software was used to predict wax appearance temperature at atmospheric pressure and temperature. Solid fraction isobar was generated using the software. The viscosity of the crude oil at different temperatures considering the pour point and different shear rates was measured using MV DIN Sensor system and M-5 measuring system of Haake viscometer.