bluuebunny/crossref_metadata_2025_split huggingface dataset:
Transcultural Experience and Multiple Biographies as a Research Topic
Authors: Falski Maciej 
Published: January 2015

Transcultural Experience and Multiple Biographies as a Research TopicTransculturality refers to the traditional understanding of culture as self-contained, concentrated around its own center and producing clear borders. “Trans” signifies the act of crossing; it signifies overcoming such borders. It looks at phenomena, people, and notions that are not limited to one communicational environment, but are represented in multiple locations, or contexts. Or rather—they cannot be fully ascribed to one “culture,” because they exhibit, traits of both (or more) cultures. Culture studies often describe, also, people with “trans” life stories; it is not a matter of simple crossing of borders, living a bit in one environment and a bit in another. The point is that their sense of belonging is of a mixed, ambiguous character, and their identity is blurred. It is a question of practices that they draw from two or more sources, creating a peculiar amalgam characteristic of living “in between.” Transculturality, just like multiple biographies, means both partial belonging and dual belonging, which is very well illustrated by the case studies presented in the volume: they have in a way, varied roots, which means they bear unique, hybrid fruit. Doświadczenie transkulturowe i biografie wielorakie jako temat badawczyTranskulturowość odnosi się do tradycyjnego pojmowania kultury jako samowystarczalnej, skoncentrowanej na sobie i wytwarzającej wyraźne granice. Przyrostek „trans” oznacza akt przekraczania tak wytyczonych granic. Kategoria transkulturowości skłania do patrzenia na zjawiska, biografie i pojęcia jako coś, co nie ogranicza się do jednego środowiska komunikacyjnego, lecz występuje bądź przejawia się w wielu miejscach i kontekstach. Można też powiedzieć, że nie można ich przypisać do jednej „kultury”, ponieważ reprezentują cechy dwóch (lub więcej) wspólnot kulturowych. Studia kulturowe często zajmują się osobami, czyje historie życia mają taki właśnie charakter „trans-graniczny” charakter. Nie chodzi przy tym jedynie o proste przejście granic, życie trochę w jednym, a trochę w drugim środowisku. Istotne jest to, że poczucie przynależności staje się niejasne lub wielorakie. Pojawia się na przykład kwestia praktyk związanych z dwoma lub więcej źródłami wzorców, co tworzy specyficzny amalgamat życia „pomiędzy”. Transkulturowość, podobnie jak biografie wielorakie, oznacza zarówno częściową, jak i zróżnicowaną identyfikację, którą świetnie ilustrują studia przypadków przedstawione w trzecim numerze „Colloquia Humanistica”; można by rzec, iż mają one różnorodne korzenie, przez co rodzą wyjątkowe, hybrydyczne owoce.
Sécurité à domicile et troubles mentaux graves : élaboration d’un outil d’évaluation
Authors: Désormeaux-Moreau Marjorie , Dumont Claire , Larivière Ginette Aubin et Nadine 
Published: January 2015

Background. Home safety evaluation is an important issue within the context of current perspectives on accommodation for people with a serious mental illness who favour a more independent way of life. Purpose. This paper describes the development and content validation of the Évaluation de la sécurité à domicile et de la gestion des risques (ESGR), an occupational therapy assessment tool for people with a serious mental illness. Method. The ESGR was developed from scientific knowledge and clinical experience. Assessing content validity was done in two phases and involved the consultation of 11 experts. Findings. In its current form, the ESGR includes 67 items organized into three categories (environment, occupation, person). Implications. According to the experts consulted, there is a clinical interest in using the ESGR to support occupational therapists in the assessment of home safety for people with serious mental illness. The statements are clear and representative of the concept and the target audience.
A randomised controlled trial comparing compression therapy after radiofrequency ablation for primary great saphenous vein incompetence
Authors: Krasznai AG , Sigterman TA , Troquay SAM , Houtermans-Auckel JP , Snoeijs MGJ , Rensma HG , Sikkink CJJM , Bouwman LH 
Published: January 2015

Background Optimal duration of leg compression after venous ablation remains unclear. This randomised controlled trial evaluates 4 h compared to 72 h of leg compression. Methods Patients were randomised to 4 or 72 h of leg compression after radiofrequency ablation of the great saphenous vein. Primary outcome was change in leg volume after 14 days. Secondary outcomes were postoperative pain, complications and time to full recovery. Results Patients wearing compression stockings for 4 h after treatment had a 64 mL (95%CI: − 23 to + 193) reduction in leg volume, compared to an increase of 21 mL (95%CI: 8.33–34.5) in patients wearing compression stockings for 72 h ( P = 0.12). Patients wearing compression stockings for 4 h experienced fewer complications (16% vs. 33%, P = 0.05). Postoperative pain and time to full recovery did not differ significantly. Conclusion Wearing compression stockings for 4 h is non-inferior in preventing leg oedema as wearing compression stockings for 72 h.
Does Obesity Affect Outcomes in Hip Arthroscopy?
Authors: Gupta Asheesh , Redmond John M. , Hammarstedt Jon E. , Stake Christine E. , Domb Benjamin G. 
Published: January 2015

Background: Hip arthroscopy has gained popularity over the past decade, and its indications have broadened as newer techniques have been developed. However, there has been a paucity of literature evaluating the outcomes of hip arthroscopy in obese patients. Purpose: To compare 2-year clinical outcomes of obese patients undergoing primary hip arthroscopy with matched nonobese controls. Study Design: Cohort study; Level of evidence, 3. Methods: From February 2008 to February 2012, data were collected prospectively on all obese patients undergoing primary hip arthroscopy. A matched-pair nonobese control group was selected at a 1:2 ratio. All patients were assessed pre- and postoperatively with 4 patient-reported outcome (PRO) measures: the modified Harris Hip Score, Non-Arthritic Hip Score, Hip Outcome Score–Activities of Daily Living, and Hip Outcome Score–Sport Specific Subscale. Pain was estimated on the visual analog scale, and satisfaction was measured on a scale from 0 to 10. Results: Sixty-two hips (62 patients) were included in the obese group and 124 hips (124 patients) in the control group. At preoperative baseline, the obese group had significantly lower PRO scores when compared with the control group. Both groups demonstrated statistically significant postoperative improvement in all scores ( P < .05). Absolute scores were significantly lower in the obese group for all PRO measures, pre- and postoperatively. However, the improvement (delta) in PRO scores from pre- to postoperative time was not significantly different between groups. The rate of conversion to total hip arthroplasty, the rate of revision, and the complication rate were not significantly different between the 2 groups; however, rates of conversion to total hip arthroplasty and revision tended to be twice as high in the obese patients, but the study was not powered for these 2 outcomes. Conclusion: Overall, obese patients had lower absolute PRO scores preoperatively and at 2-year follow-up. Both obese and nonobese patients demonstrated significant improvement in all PRO scores, and the change in scores were similar between groups. These results indicate that while obese patients may not have similar absolute scores after hip arthroscopy, they may show similar gains in improvement when compared with baseline. Hip arthroscopy appears to be a viable treatment option in the obese patient as long as expectations are adjusted accordingly.
Assessing patient satisfaction with a multidisciplinary gender dysphoria clinic in Melbourne
Authors: Erasmus Jaco , Bagga Harjit , Harte Fintan 
Published: January 2015

Objectives: The Gender Dysphoria Clinic in Melbourne, Australia, assessed patient outcome by focusing on patients’ subjective evaluation of the healthcare services they received through the clinic. Methods: A satisfaction survey, which was previously used in two established gender clinics in the US and UK, was adapted and then administered to consecutive patients who attended the Gender Dysphoria Clinic during a 1-month period. Results: A total of 127 surveys were available for analysis: 88% of patients reported being satisfied with the services they received. Patients’ perceived level of distress reduced significantly, following their involvement with the Gender Dysphoria Clinic. Feeling understood and heard in a non-judgmental manner by a specialist in the field of gender dysphoria was the most positive aspect of service provision. The most negative aspect of the clinic was a lengthy waiting list. Conclusions: Although the majority of trans-and-gender-diverse patients attending the Gender Dysphoria Clinic were satisfied with the service they received, there is a need to identify strategies to facilitate timely access to the clinic.
Developing Safety and Risk Assessment Tools and Training Materials
Authors: Spies Gloudina M. , Delport Catharina S. L. , le Roux Magdalena P. 
Published: January 2015

Purpose: This article presents the results of a two-phase dialogue between social work practitioners and researchers regarding the development and implementation of safety and risk assessment tools and training materials for social workers in the South African context. Methods: The first phase of the dialogue included interviews with 81 professionals to determine current practices in safety and risk assessment, resulting in the development of assessment tools and training materials. The second phase involved dialogue with 13 social workers who attended a workshop on the developed safety and risk assessment tools and who were able to implement the tools in practice. Results: A need for uniform safety and risk assessment tools and procedures was identified, and encouraging evidence indicated the effectiveness of the developed tools. Discussion: Constructive dialogue between practice and research was instrumental in developing and implementing safety and risk assessment tools and training materials for the South African context.
Social work interventions on intimate partner violence against women in China
Authors: Tam Dora MY , Schleicher Katherine , Wu Wenmei , Kwok Siu-Ming , Thurston Wilfreda E , Dawson Myrna 
Published: January 2015

Summary Intimate Partner Violence (IPV) affects approximately one-fifth of women during their lifetime in China. However, limited studies have been conducted in China among women and service providers on IPV. The study reported in this article used an Ecological Model and the Capabilities Perspective integrated with the Advocacy Intervention Model as the theoretical framework for guiding the research and data analysis. This study was part of a participatory project to develop appropriate social work interventions in Guangzhou, China. Findings Twenty-one women who experienced IPV and 30 service providers were interviewed for their views on barriers to help-seeking processes, needs and concerns of this population, and recommendations for any changes. The results of this study clearly suggest that gender inequality is the root cause of IPV against women and prevents women from leaving a violent relationship. Applications The results suggest a number of needed changes at micro, meso, exo, and macro levels and the ways in which social workers can act as advocates for the changes in the context of Guangzhou.
Factor VIII gene variants and inhibitor risk in African American hemophilia A patients
Authors: Gunasekera Devi , Ettinger Ruth A. , Nakaya Fletcher Shelley , James Eddie A. , Liu Maochang , Barrett John C. , Withycombe Janice , Matthews Dana C. , Epstein Melinda S. , Hughes Richard J. , Pratt Kathleen P. 
Published: January 2015

Key Points
Immune responses to FVIII sequence variants encoded by ns-SNPs do not contribute appreciably to inhibitor development in African Americans. African American HA subjects with an intron-22 inversion had a 2- to 3-times-higher inhibitor incidence than whites with the same mutation.
Increasing the inspiratory time and I:E ratio during mechanical ventilation aggravates ventilator-induced lung injury in mice
Authors: Müller-Redetzky Holger C , Felten Matthias , Hellwig Katharina , Wienhold Sandra-Maria , Naujoks Jan , Opitz Bastian , Kershaw Olivia , Gruber Achim D , Suttorp Norbert , Witzenrath Martin 
Published: January 2015

Abstract
Introduction
Lung-protective ventilation reduced acute respiratory distress syndrome (ARDS) mortality. To minimize ventilator-induced lung injury (VILI), tidal volume is limited, high plateau pressures are avoided, and positive end-expiratory pressure (PEEP) is applied. However, the impact of specific ventilatory patterns on VILI is not well defined. Increasing inspiratory time and thereby the inspiratory/expiratory ratio (I:E ratio) may improve oxygenation, but may also be harmful as the absolute stress and strain over time increase. We thus hypothesized that increasing inspiratory time and I:E ratio aggravates VILI.

Methods
VILI was induced in mice by high tidal-volume ventilation (HVT 34 ml/kg). Low tidal-volume ventilation (LVT 9 ml/kg) was used in control groups. PEEP was set to 2 cm H2O, FiO2 was 0.5 in all groups. HVT and LVT mice were ventilated with either I:E of 1:2 (LVT 1:2, HVT 1:2) or 1:1 (LVT 1:1, HVT 1:1) for 4 hours or until an alternative end point, defined as mean arterial blood pressure below 40 mm Hg. Dynamic hyperinflation due to the increased I:E ratio was excluded in a separate group of animals. Survival, lung compliance, oxygenation, pulmonary permeability, markers of pulmonary and systemic inflammation (leukocyte differentiation in lung and blood, analyses of pulmonary interleukin-6, interleukin-1β, keratinocyte-derived chemokine, monocyte chemoattractant protein-1), and histopathologic pulmonary changes were analyzed.

Results
LVT 1:2 or LVT 1:1 did not result in VILI, and all individuals survived the ventilation period. HVT 1:2 decreased lung compliance, increased pulmonary neutrophils and cytokine expression, and evoked marked histologic signs of lung injury. All animals survived. HVT 1:1 caused further significant worsening of oxygenation, compliance and increased pulmonary proinflammatory cytokine expression, and pulmonary and blood neutrophils. In the HVT 1:1 group, significant mortality during mechanical ventilation was observed.

Conclusion
According to the “baby lung” concept, mechanical ventilation-associated stress and strain in overinflated regions of ARDS lungs was simulated by using high tidal-volume ventilation. Increase of inspiratory time and I:E ratio significantly aggravated VILI in mice, suggesting an impact of a “stress/strain × time product” for the pathogenesis of VILI. Thus increasing the inspiratory time and I:E ratio should be critically considered.
Netrins and Frazzled/DCC promote the migration and mesenchymal to epithelial transition of Drosophila midgut cells
Authors: Pert Melissa , Gan Miao , Saint Robert , Murray Michael J. 
Published: January 2015

ABSTRACT
Mesenchymal-epithelial transitions (METs) are important in both development and the growth of secondary tumours. Although the molecular basis for epithelial polarity is well studied, less is known about the cues that induce MET. Here we show that Netrins, well known as chemotropic guidance factors, provide a basal polarising cue during the Drosophila midgut MET. Both netrinA and netrinB are expressed in the visceral mesoderm, the substrate upon which midgut cells migrate, while their receptor frazzled (fra) is expressed in midgut cells. Netrins are required to polarise Fra to the basal surface, and Netrins and Fra undergo mutually-dependent endocytosis, with Fra subsequently trafficking to late endosomes. Mutations to fra and netrins affect both migration and MET but to different degrees. Loss of fra strongly delays migration, midgut cells fail to extend protrusions, and apico-basal polarisation of proteins and epithelium formation is inhibited. In netrin mutants, the migration phenotype is weaker and cells still extend protrusions. However, apico-basal polarisation of proteins, including Fra, and FActin is greatly disrupted and a monolayer fails to form. Delocalised accumulations of FActin are prevalent in netrin mutants but not fra mutants suggesting delocalised Fra may disrupt the MET. βPS localisation is also affected in netrin mutants in that a basal gradient is reduced while localisation to the midgut/VM interface is increased. Since a similar effect is seen when endocytosis is inhibited, Netrin and Fra may regulate Integrin turnover. The results suggest Netrin-dependent basal polarisation of Fra is critical for the formation of an epithelium.
mir-34b/c and mir-449a/b/c are required for spermatogenesis, but not for the first cleavage division in mice
Authors: Yuan Shuiqiao , Tang Chong , Zhang Ying , Wu Jingwen , Bao Jianqiang , Zheng Huili , Xu Chen , Yan Wei 
Published: January 2015

ABSTRACT
Mammalian sperm are carriers of not only the paternal genome, but also the paternal epigenome in the forms of DNA methylation, retained histones and noncoding RNAs. Although paternal DNA methylation and histone retention sites have been correlated with protein-coding genes that are critical for preimplantation embryonic development, physiological evidence of an essential role of these epigenetic marks in fertilization and early development remains lacking. Two miRNA clusters consisting of five miRNAs (miR-34b/c and miR-449a/b/c) are present in sperm, but absent in oocytes, and miR-34c has been reported to be essential for the first cleavage division in vitro. Here, we show that both miR-34b/c- and miR-449-null male mice displayed normal fertility, and that intracytoplasmic injection of either miR-34b/c- or miR-449-null sperm led to normal fertilization, normal preimplantation development and normal birth rate. However, miR-34b/c and miR-449 double knockout (miR-dKO) males were infertile due to severe spermatogenic disruptions and oligo-astheno-teratozoospermia. Injection of miR-dKO sperm into wild-type oocytes led to a block at the two-pronucleus to zygote transition, whereas normal preimplantation development and healthy pups were obtained through injection of miR-dKO round spermatids. Our data demonstrate that miR-34b/c and miR-449a/b/c are essential for normal spermatogenesis and male fertility, but their presence in sperm is dispensable for fertilization and preimplantation development.
Variation in early-life telomere dynamics in a long-lived bird: links to environmental conditions and survival
Authors: Watson Hannah , Bolton Mark , Monaghan Pat 
Published: January 2015

ABSTRACT
Conditions experienced during early life can have profound consequences for both short- and long-term fitness. Variation in the natal environment has been shown to influence survival and reproductive performance of entire cohorts in wild vertebrate populations. Telomere dynamics potentially provide a link between the early environment and long-term fitness outcomes, yet we know little about how the environment can influence telomere dynamics in early life. We found that environmental conditions during growth have an important influence on early-life telomere length (TL) and attrition in nestlings of a long-lived bird, the European storm petrel Hydrobates pelagicus. Nestlings reared under unfavourable environmental conditions experienced significantly greater telomere loss during postnatal development compared with nestlings reared under more favourable natal conditions, which displayed a negligible change in TL. There was, however, no significant difference in pre-fledging TL between cohorts. The results suggest that early-life telomere dynamics could contribute to the marked differences in life-history traits that can arise among cohorts reared under different environmental conditions. Early-life TL was also found to be a significant predictor of survival during the nestling phase, providing further evidence for a link between variation in TL and individual fitness. To what extent the relationship between early-life TL and mortality during the nestling phase is a consequence of genetic, parental and environmental factors is currently unknown, but it is an interesting area for future research. Accelerated telomere attrition under unfavourable conditions, as observed in this study, might play a role in mediating the effects of the early-life environment on later-life performance.
The role of egg-nest contrast in the rejection of brood parasitic eggs
Authors: Aidala Zachary , Croston Rebecca , Schwartz Jessica , Tong Lainga , Hauber Mark E. 
Published: January 2015

Abstract
Hosts of avian brood parasites can avoid the reproductive costs of raising genetically unrelated offspring by rejecting parasitic eggs. The perceptual cues and controls mediating parasitic egg discrimination and ejection are well studied: hosts are thought to use differences in egg color, brightness, maculation, size, and shape to discriminate between own and foreign eggs. Most models of brood parasitism implicitly assume that the primary criteria to which hosts attend when discriminating eggs are differences between the eggs themselves. However, this assumption is confounded by the degree to which chromatic and achromatic characteristics of the nest lining co-vary with egg coloration, in that egg-nest contrast per se might be the recognition cue driving parasitic egg detection. Here we systematically tested whether and how egg-nest contrast itself contributes to foreign egg discrimination. In an artificial parasitism experiment, we independently manipulated egg color and nest lining color of the egg-ejector American robin (Turdus migratorius), a host of the obligate brood parasitic brown-headed cowbird (Molothrus ater). We hypothesized that the degree of contrast between foreign eggs and the nest background would affect host egg rejection behavior. We predicted that experimentally decreasing egg-nest chromatic and achromatic contrast (i.e. rendering parasitic eggs more cryptic against the nest lining) would decrease rejection rates, while increasing egg-nest contrast would increase rejection rates. In contrast to our predictions, egg-nest contrast was not a significant predictor of egg ejection patterns. Instead, egg color significantly predicted responses to parasitism. We conclude that egg-egg differences are the primary drivers of egg rejection in this system. Future studies should test for the effects of egg-nest contrast per se in predicting parasitic egg recognition in other host-parasite systems, including those hosts building enclosed nests and parasites laying cryptic eggs, as an alternative to hypothesized effects of egg-egg contrasts.