bluuebunny/crossref_metadata_2025_split huggingface dataset:
Change in Identity Diffusion and Psychopathology in a Specialized Inpatient Treatment for Borderline Personality Disorder
Authors: Sollberger Daniel , Gremaud‐Heitz Daniela , Riemenschneider Anke , Agarwalla Puspa , Benecke Cord , Schwald Oliver , Küchenhoff Joachim , Walter Marc , Dammann Gerhard 
Published: August 2014

ObjectivesPatients with borderline personality disorder (BPD) show various psychopathological symptoms and suffer especially from disturbance in their identity. The purpose of the study was to investigate changes—particularly in affective BPD symptoms and identity diffusion—during a structured, disorder‐specific inpatient treatment (DST) that combined a psychodynamic transference‐focused psychotherapy approach with modules of dialectical behavioural skills training.MethodIn a prospective, two‐group comparison trial, 44 patients with BPD were assessed with questionnaires addressing identity diffusion and state, as well as trait affective psychopathology, before and after 12 weeks of inpatient treatment. Thirty‐two patients received DST, whereas 12 patients were given inpatient treatment‐as‐usual (TAU). The patients were allocated in a non‐random procedure for two groups, in order of admission and availability of treatment options in the DST unit.ResultsIn the pre‐post‐comparison, the DST group showed a significant decrease in identity diffusion (p < 0.001) and improvements in instability of the image of self and others (p < 0.008), as well as in pathological (trait and state) symptoms. However, there was no significant improvement in the TAU group.ConclusionsAfter a 12‐week inpatient treatment, the findings indicate significant improvements in the DST group in typical affective borderline symptomatology and in the personality structure feature of identity diffusion. This highlights the significance of a short‐term specific inpatient therapy for BPD.Key Practitioner Message

A structured, disorder‐specific inpatient treatment of patients diagnosed with borderline personality disorder (BPD) combined a psychodynamic transference‐focused psychotherapy treatment approach (focusing on pathological features in personality organization, particularly on non‐integrated images of self and others) with modules of dialectical behavioural skills training. This treatment is associated with a decrease in identity diffusion of these patients after 12 weeks of treatment.
The treatment is also related to a significant decrease in borderline typical psychopathological symptoms such as depressive symptoms, as well as an improvement in state anger.
The outcomes of this structured, disorder‐specific inpatient treatment of severely ill BPD patients indicated the relevance of intensive short‐term inpatient psychotherapy in terms of psychopathological improvements as well as initial changes in structural personality organization.
Copyright © 2014 John Wiley & Sons, Ltd.
Central coherence in adolescents with bulimia nervosa spectrum eating disorders
Authors: Darcy Alison M. , Fitzpatrick Kathleen Kara , Manasse Stephanie M. , Datta Nandini , Klabunde Megan , Colborn Danielle , Aspen Vandana , Stiles‐Shields Colleen , Labuschagne Zandre , Le Grange Daniel , Lock James 
Published: August 2014

ABSTRACTBackgroundWeak central coherence—a tendency to process details at the expense of the gestalt—has been observed among adults with bulimia nervosa (BN) and is a potential candidate endophenotype for eating disorders (EDs). However, as BN behaviors typically onset during adolescence it is important to assess central coherence in this younger age group to determine whether the findings in adults are likely a result of BN or present earlier in the evolution of the disorder. This study examines whether the detail‐oriented and fragmented cognitive inefficiency observed among adults with BN is observable among adolescents with shorter illness duration, relative to healthy controls.MethodThe Rey‐Osterrieth Complex Figure Test (RCFT) was administered to a total of 47 adolescents with DSM5 BN, 42 with purging disorder (PD), and 25 healthy controls (HC). Performance on this measure was compared across the three groups.ResultsThose with BN and PD demonstrated significantly worse accuracy scores compared to controls in the copy and delayed recall condition with a moderate effect size. These findings were exacerbated when symptoms of BN increased.DiscussionPoorer accuracy scores reflect a fragmented and piecemeal strategy that interferes with visual‐spatial integration in BN spectrum disorders. This cognitive inefficiency likely contributes to broad difficulties in executive functioning in this population especially in the context of worsening bulimic symptoms. The findings of this study support the hypothesis that poor global integration may constitute a cognitive endophenotype for BN.
A K2CO3‐Mediated Regioselective Synthesis of Indole/Pyrrole‐Fused 1,4‐Oxazines: An Unexpected Indole‐Fused Azlactone Synthesis
Authors: Vandavasi Jaya Kishore , Hu Wan‐Ping , Senadi Gopal Chandru , Boominathan Siva Senthil Kumar , Chen Hsing‐Yin , Wang Jeh‐Jeng 
Published: August 2014

AbstractA highly regioselective and efficient base‐catalyzed intramolecular hydroalkoxylation of primary and secondary alkynyl alcohols was developed to afford 1,4‐oxaza heterocycles. Although the rates of cyclization for terminal alkynyl alcohols were significantly greater than those for internal ones, our method tolerated both terminal and internal alkynes. In addition, an unprecedented one‐pot hydroamination reaction was found to proceed with high chemo‐ and regioselectivity to form indole‐fused azlactones in the presence of base.
Visualization of controlled fragrance release from cyclodextrin inclusion complexes by fluorescence imaging
Authors: Liu Chuanjun , Hayashi Kenshi 
Published: August 2014

ABSTRACTEvaluation of odour release is important for the development of encapsulated fragrances. However, the use of existing instrumental analysis or gas‐sensor technologies for odour‐release evaluation is time‐ and labour‐consuming. This paper introduces a fluorescence imaging system that can be used as a simple but effective tool to visualize the moisture‐activated release of fragrance from cyclodextrin inclusion complexes. The visualization is based on the fluorescence changes of samples caused by the release of fragrance molecules from the cavity of cyclodextrin. Fluorescence spectroscopy investigations proved that different strategies could be used in the visualization depending on the molecular characters of the encapsulated fragrances. In the case of fragrance molecules with fluorescence (typically methyl anthranilate: MA), the change of fluorescence intensity was derived from the changed microenvironment of MA – from the encapsulated state to the released state. For the fragrance molecules without fluorescence (typically menthol), an appropriate fluorescent probe (7‐amino‐4‐methylcoumarin: AMC) was used, and the fluorescence change was observed due to the interactions between AMC and the released menthol molecules. The real‐time releases were visualized by two‐dimensional/three‐dimensional surface plots of the fluorescence images using image‐processing software. Both the burst release occurring on the short time scale and the slow, natural release in ambient conditions can be demonstrated by the proposed visualization technique. Copyright © 2014 John Wiley & Sons, Ltd.
Environmental Strategies: Strategies for Compliance With Mercury and Air Toxics Standards
Authors: Sebor Stephanie 
Published: August 2014

AbstractThe Environmental Protection Agency's Mercury and Air Toxics Standards (MATS) rule comes into effect for existing coal‐ and oil‐fired electric utility steam generating units (EGUs) on April 16, 2015. This article summarizes the rule's requirements and sets forth considerations for affected sources evaluating their compliance options under the rule.
Depression and anxiety symptoms in male veterans and non‐veterans: the Health and Retirement Study
Authors: Gould Christine E. , Rideaux Tiffany , Spira Adam P. , Beaudreau Sherry A. 
Published: August 2014

ObjectivesWe examined whether veteran status was associated with elevated depression and anxiety symptoms in men aged 50 and older after adjusting for sociodemographic factors.MethodsParticipants were 6577 men aged 50 years and older who completed the 2006 wave of the Health and Retirement Study (HRS). Forty‐nine percent of participants were veterans. A randomly selected subset of participants completed the HRS Psychosocial Questionnaire (N = 2957), which contained the anxiety items. Elevated depression and anxiety symptoms were determined based on brief versions of Center for Epidemiologic Studies—Depression Scale (CES‐D total score ≥ 4) and Beck Anxiety Inventory (BAI total score ≥ 12).ResultsElevated depression and anxiety symptoms were found in 11.0 and 9.9% of veterans, respectively, compared with 12.8 and 12.3% of non‐veterans. Veteran status was not associated with increased odds of anxiety or depression symptoms in the multivariable‐adjusted logistic regression analyses. Additional analyses indicated that Vietnam War veterans were more than twice as likely as World War II or Korean War veterans to have elevated depression symptoms (OR = 2.15, 95% CI: 1.54–3.00) or anxiety symptoms (OR = 2.12, 95% CI: 1.28–3.51).ConclusionsIn a community‐based sample of men aged 50 and older, veteran status was not associated with the presence of elevated depression and anxiety symptoms. Rather, these symptoms were associated with age, ethnicity, education, and medical conditions. Among veterans, cohort effects accounted for differences in psychiatric symptoms. Including younger cohorts from the Global War on Terror may yield different results in future studies. Copyright © 2014 John Wiley & Sons, Ltd.
A New and Convenient Synthesis of Amino‐phthalimide (1H‐Isoindole‐1,3(2H)‐dione) Derivatives and Their Photoluminescent Properties
Authors: Tan Ayse , Bozkurt Ebru , Kishali Nurhan , Kara Yunus 
Published: August 2014

AbstractA new and convenient synthesis for amino‐phthalimide (1H‐isoindole‐1,3(2H)‐dione) derivatives has been developed starting from an α,β‐unsaturated ketone. The ketones were reacted with amines to give aromatic amine products. This is the first time that substituted amine groups have been incorporated in aromatic rings. The mechanism of the product formation is rationalized by the 1,2‐addition of amines to ketones. All aromatic compounds exhibited high fluorescence properties at the blue‐green region.
Copper‐Catalyzed Synthesis of Alkynyl Hydrazones from Alkynes and Hydrazonyl Chlorides
Authors: Yavari Issa , Nematpour Manijeh , Yavari Sima , Sadeghizadeh Fatemeh 
Published: August 2014

AbstractA novel ligand‐free synthesis of alkynyl hydrazones via coupling reaction of hydrazonyl chlorides and terminal alkynes, catalyzed by CuI led to excellent yields.
Two New Acidic Diterpenoids from the Heartwood of Pinus massonianaLamb.
Authors: Abd. Mohamed H. , Hsieh Chin‐Lin , Hsu Chin , Kuo Ching‐Chuan , Chang Hsuan‐Shuo , Lee Ching‐Kuo , Lee Tzon‐Huei , Wu Jin‐Bin , Chang Chi‐I , Kuo Yueh‐Hsiung 
Published: August 2014

AbstractA new abietane diterpene, named abietopinoic acid, and a new podocarpane diterpene, named podopinoic acid, were isolated from the acetone extract of the heartwood of Pinus massoniana. Their structures were established as 12‐hydroxy‐7‐oxoabieta‐8,11,13‐trien‐18‐oic acid (1) and 13‐hydroxy‐7‐oxopodocarpane (2) by means of spectroscopic analyses including 2D‐NMR. To the best of our knowledge, this is the second report of a podocarpa‐8,11,13‐trien‐18‐oic acid diterpene, isolated from the genus Pinus.
Cortical Thickness of the Femur and Long-Term Bisphosphonate Use
Authors: Niimi Rui , Kono Toshibumi , Nishihara Atsushi , Hasegawa Masahiro , Matsumine Akihiko , Kono Toshihiko , Sudo Akihiro 
Published: August 2014

ABSTRACT

Femoral cortical thickening has been mentioned in reports of atypical subtrochanteric/femoral shaft (ST/FS) fractures, which are associated with long-term bisphosphonate (BP) use. However, whether thickening precedes BP use or results from BP use, as well as the role BPs may play in cortical thickening remain unclear. The purpose of this study was to investigate the relationship between cortical thickness and BP use. We enrolled 142 patients (mean age 79 years) who had taken BPs for more than 5 years, and enrolled 426 osteoporosis patients who had not used BPs as controls. We performed a case-control study of patients with long-term BP use and controls matched for age, sex, and levels of activities of daily living (ADLs) (1:3 ratio). On femoral radiographs, we measured femoral cortical thickness in three regions: 5 cm and 12.5 cm below the lesser trochanter and in the region of maximal cortical thickness. We compared cortical thicknesses between patients taking BP and controls and evaluated longitudinal changes in cortical thickness. There were no significant differences in cortical thickness between long-term BP users and controls. In addition, after further use of BP for a minimum of 1 year, we observed no significant differences in the changes in cortical thickness at any level of the femur. In conclusion, our study did not find evidence of cortical thickening at the ST/FS area of the femur with long-term BP use. © 2014 American Society for Bone and Mineral Research.
Intraoperative ultrasound to facilitate removal of a submucosal foreign body
Authors: Smith Matthew E. , Riffat Faruque , Berman Laurence H. , Jani Piyush 
Published: August 2014

ABSTRACTA 61‐year‐old man with a history of fish bone ingestion and poorly localized symptoms was seen. His clinical examination was unremarkable, but CT demonstrated a foreign body deeply embedded within his tongue. Intraoperative ultrasound (US) guidance facilitated identification of a bone, allowing a needle to be placed as a guide to dissection. Repeat US scanning through the incision permitted precisely targeted surgery. CT and US are the most effective imaging techniques for localizing fish bones. Intraoperative US can be used to accurately locate a submucosal fish bone in mobile tissue such as the tongue, and focused, image‐guided dissection can reduce surgical tissue trauma. © 2014 Wiley Periodicals, Inc. J Clin Ultrasound 42:565–568, 2014
Effect ofAloe veraapplication on the content and molecular arrangement of glycosaminoglycans during calcaneal tendon healing
Authors: De Aro Andrea Aparecida , Esquisatto Marcelo Augusto Marretto , Nishan Umar , Perez Mylena Oliveira , Rodrigues Rodney Alexandre Ferreira , Foglio Mary Ann , De Carvalho João Ernesto , Gomes Laurecir , Vidal Benedicto De Campos , Pimentel Edson Rosa 
Published: August 2014

ABSTRACTAlthough several treatments for tendon lesions have been proposed, successful tendon repair remains a great challenge for orthopedics, especially considering the high incidence of re‐rupture of injured tendons. Our aim was to evaluate the pharmacological potential ofAloe veraon the content and arrangement of glycosaminoglycans (GAGs) during tendon healing, which was based on the effectiveness ofA. veraon collagen organization previously observed by our group. In rats, a partial calcaneal tendon transection was performed with subsequent topicalA. veraapplication at the injury site. The tendons were treated withA. veraointment for 7 days and excised on the 7th, 14th, or 21stday post‐surgery. Control rats received ointment withoutA. vera. A higher content of GAGs and a lower amount of dermatan sulfate were detected in theA. vera‐treated group on the 14thday compared with the control. Also at 14 days post‐surgery, a lower dichroic ratio in toluidine blue stained sections was observed inA. vera‐treated tendons compared with the control. No differences were observed in the chondroitin‐6‐sulfate and TGF‐β1 levels between the groups, and higher amount of non‐collagenous proteins was detected in theA. vera‐treated group on the 21stday, compared with the control group. No differences were observed in the number of fibroblasts, inflammatory cells and blood vessels between the groups. The application ofA. veraduring tendon healing modified the arrangement of GAGs and increased the content of GAGs and non‐collagenous proteins.Microsc. Res. Tech. 77:964–973, 2014. © 2014 Wiley Periodicals, Inc.
Systematic review of the use of bone cement in ossicular chain reconstruction and revision stapes surgery
Authors: Wegner Inge , van den Berg Jelle W.G. , Smit Adriana L. , Grolman Wilko 
Published: August 2014

Objectives/HypothesisTo evaluate the effectiveness of bone cement on mean postoperative air–bone gap (ABG) and the proportion of ABG closure to within 20 dB in patients undergoing ossicular chain reconstruction or revision stapes surgery.Data SourcesPubMed, Embase, and Central.MethodsA systematic search was conducted. Studies reporting original study data were included. Relevance and risk of bias (RoB) of the selected articles were assessed. Studies with low relevance, high RoB, or both were excluded. Mean differences, risk differences, and their 95% confidence intervals were extracted for the outcomes of interest.ResultsTwelve studies with high relevance and moderate RoB were included for data extraction. Seven of these were two‐armed studies, and five were one‐armed studies. ABG closure to within 20 dB was assessed in 11 studies and achieved in 60% to 94% of patients who were treated with bone cement. Mean ABG closure ranged from 15 dB to 23 dB in patients treated with bone cement across 11 studies. Most of the two‐armed studies did not show a statistically significant difference between the use of bone cement and various conventional rebridging techniques, including allograft or autograft interposition and partial ossicular replacement prosthesis.ConclusionThere is no sufficient evidence to support superiority of use of bone cement compared to conventional techniques. It seems from the available evidence that bone cement does not underachieve in ossiculoplasty compared to conventional rebridging techniques. Laryngoscope, 125:227–233, 2015
No association between apolipoprotein E or N‐Acetyltransferase 2 gene polymorphisms and age‐related hearing loss
Authors: Dawes Piers , Platt Hazel , Horan Michael , Ollier William , Munro Kevin , Pendleton Neil , Payton Antony 
Published: August 2014

Objectives/HypothesisAge‐related hearing loss has a genetic component, but there have been limited genetic studies in this field. Both N‐acetyltransferase 2 and apolipoprotein E genes have previously been associated. However, these studies have either used small sample sizes, examined a limited number of polymorphisms, or have produced conflicting results. Here we use a haplotype tagging approach to determine association with age‐related hearing loss and investigate epistasis between these two genes.Study DesignCandidate gene association study of a continuous phenotype.MethodsWe investigated haplotype tagging single nucleotide polymorphisms in the N‐acetyltransferase 2 gene and the presence/absence of the apolipoprotein E ε4 allele for association with age‐related hearing loss in a cohort of 265 Caucasian elderly volunteers from Greater Manchester, United Kingdom. Hearing phenotypes were generated using principal component analysis of the hearing threshold levels for the better ear (severity, slope, and concavity). Genotype data for the N‐acetyltransferase 2 gene was obtained from existing genome‐wide association study data from the Illumina 610‐Quadv1 chip. Apolipoprotein E genotyping was performed using Sequenom technology. Linear regression analysis was performed using Plink and Stata software.ResultsNo significant associations (P value, > 0.05) were observed between the N‐acetyltransferase 2 or apolipoprotein E gene polymorphisms and any hearing factor. No significant association was observed for epistasis analysis of apolipoprotein E ε4 and the N‐acetyltransferase 2 single nucleotide polymorphism rs1799930 (NAT2*6A).ConclusionWe found no evidence to support that either N‐acetyltransferase 2 or apolipoprotein E gene polymorphisms are associated with age‐related hearing loss in a cohort of 265 elderly volunteers.Level of EvidenceN/A. Laryngoscope, 125:E33–E38, 2015
Esophageal perforation caused by edible foreign bodies: A systematic review of the literature
Authors: Aronberg Ryan M. , Punekar Salman R. , Adam Stewart I. , Judson Benjamin L , Mehra Saral , Yarbrough Wendell G. 
Published: August 2014

Objectives/HypothesisPresentation of a case of esophageal perforation caused by ingestion of a foreign body that was difficult to visualize endoscopically, and systematic review of the current literature with a focus on available diagnostic modalities and missed diagnoses.Data SourcesMEDLINE (1946–2014)Review MethodsWe conducted a systematic review of MEDLINE for cases and studies of esophageal perforation due to foreign bodies.ResultsA systematic review of esophageal perforations caused by foreign bodies revealed 40 studies that included 168 patients. Neck/chest pain, odynophagia, and dysphagia were the most common presenting symptoms—each occurring in the majority of patients. Where reported, diagnostic sensitivity of lateral neck X‐rays was 56%, and computed tomography (CT) scan was 100%. Nine of 168 cases specifically mentioned a missed diagnosis. Very few studies reported a failure to visualize the foreign object at the time of primary rigid or flexible esophagoscopy. No studies reported nonvisualization of the foreign body at the time of open surgery.ConclusionEsophageal perforations due to foreign bodies are rare but carry potentially devastating complications. Delays in diagnosis are common, and no standard diagnostic algorithm exists. Lateral neck X‐rays are an easy but insensitive screening test. Laryngoscopy is an excellent screening test but not always diagnostic. CT is a more sensitive diagnostic method, which can also help guide management based on the detection of complications. Although seldom described, if an object is not visualized at the time of endoscopic or surgical intervention, follow‐up CT may be useful in determining the persistence of effects of the perforation or the foreign body. Laryngoscope, 125:371–378, 2015