bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical efficacy of two vertical soft tissue augmentation techniques for peri‐implant crestal bone level stability: A randomized clinical trial
Authors: Puisys Algirdas , Vindasiute‐Narbute Egle , Razukevicius Dainius , Akhondi Samuel , Gallucci German O. , Pedrinaci Ignacio 
Published: August 2024

AbstractObjectivesThis study aimed to compare the efficacy of two techniques—acellular dermal matrix (ADM) grafting and tenting technique (TT)—for soft tissue height (STH) augmentation simultaneous to implant placement to minimize peri‐implant crestal bone level (CBL) changes.MethodsForty patients with a healed single mandibular posterior edentulous site with a thin soft tissue phenotype were enrolled. Twenty patients received simultaneously to implant placement ADM grafting, while the others received submerged healing abutment (TT). Clinical peri‐implant soft tissue height and radiographic CBL changes were measured at restoration delivery and 1‐year follow‐up.ResultsBoth techniques effectively increased soft tissue thickness, resulting in a final average STH of 3.4 ± 0.5 mm after augmentation. On average, soft tissue increased by 1.6 ± 0.5 mm in group ADM and by 1.8 ± 0.4 mm in group TT after augmentation. In Group ADM, mesial CBL decreased from 0.4 ± 0.3 mm to 0.1 ± 0.2 mm, and distal CBL decreased from 0.5 ± 0.3 mm to 0.2 ± 0.3 mm over 1 year. In Group TT, mesial CBL remained stable at 0.3 ± 0.2 mm, while distal CBL reduced slightly from 0.5 ± 0.5 mm to 0.3 ± 0.2 mm. Both groups showed minimal changes in CBL, indicating great stability (pmesial = 0.003, pdistal = 0.004). TT was particularly effective in preventing mesial bone loss (pmesial = 0.019). The mesial CBL changes significantly differed between groups (p = 0.019), and not significantly at distal sites (p = 0.944). Neither treatment exhibited significant bone remodeling below the implant shoulder.ConclusionThis study suggests that both techniques were successful in STH augmentation, and they may effectively reduce peri‐implant crestal bone level changes, with TT being slightly superior. TT was more prone to post‐surgical complications. This RCT was not registered before participant recruitment and randomization.
Magic‐themed motor training for daily bimanual task performance in children with unilateral spastic cerebral palsy: A systematic review and meta‐analysis
Authors: Lee Kuan‐Ting , Cheng Kai‐Wen , Yang Yi‐Ching , Wang Wei‐Li 
Published: August 2024

AbstractAimTo evaluate the effectiveness of magic‐themed interventions in improving daily bimanual task performance in children with unilateral spastic cerebral palsy (CP) and to elucidate the variability in outcomes.MethodThis systematic literature review searched databases including Embase, MEDLINE, Scopus, Cochrane Central, and CINAHL. Outcome measures selected for the meta‐analysis included the Children's Hand‐use Experience Questionnaire, its three subscales, and the Besta subscale C. The overall efficacy of magic‐themed interventions was analysed using Hedges' g as the summary measure for these outcomes. Subgroup analysis compared the efficacy of different modes of training, and a meta‐regression investigated the impact of training duration.ResultsAnalyses of four studies involving 78 children showed magic‐themed training significantly improved bimanual task performance (Hedges' g = 0.327, 95% confidence interval [CI] = 0.107–0.547, p = 0.004), especially in group settings (Hedges' g = 0.435, 95% CI = 0.176–0.693, p = 0.001), compared with non‐significant gains from video interventions (Hedges' g = 0.041, 95% CI = −0.380 to 0.462, p = 0.850). Additionally, training duration positively correlated with performance gains (coefficient = 0.0076 per hour, p = 0.001).InterpretationMagic‐themed training, especially through group sessions and extended durations, enhances bimanual skills in children with unilateral spastic CP.
The biogeochemical boomerang: Site fidelity creates nutritional hotspots that may promote recurrent calving site reuse
Authors: Ferraro Kristy M. , Albrecht Dara , Hendrix Jack G. , Wal Eric Vander , Schmitz Oswald J. , Webber Quinn M. R. , Bradford Mark A. 
Published: August 2024

AbstractAnimals interact with nutrient cycles by consuming and depositing nutrients, interactions studied separately in nutritional ecology and zoogeochemistry. Recent theoretical work bridges these disciplines, highlighting that animal‐driven nutrient recycling could be crucial in helping animals meet their nutritional needs. When animals exhibit site fidelity, they consistently deposit nutrients, potentially improving vegetation quality. We investigated this potential feedback by analysing changes in forage nitrogen stocks following simulated caribou calving. We found that forage nitrogen stocks increased after 2 weeks and remained elevated after 1 year, a change due to increased forage quality, not quantity. We also developed a nutrient budget within calving grounds, demonstrating that natal fluid and calf carcasses contribute substantial nitrogen subsidies. We, thus, highlight a positive zoogeochemical feedback whereby nutrients deposited during calving become bioavailable during lactation and provide evidence that site fidelity creates a biogeochemical boomerang in which animals deposit nutrients that can be reused later.
Predicting the low‐cycle fatigue life of Ti‐6Al‐4V alloy using backpropagation neural network optimized by the improved dung beetle algorithm
Authors: Gao Zihao , Zhu Changsheng , Shu Yafeng , Wang Shaohui , Wang Canglong , Chen Yupeng 
Published: August 2024

AbstractIn this study, we propose an innovative approach that enhances the performance of the backpropagation (BP) neural network in predicting the low‐cycle fatigue life of Ti‐6Al‐4V alloy by improving the dung beetle optimization (DBO) algorithm with the maximin Latin hypercube design (MLHD) strategy. To address the challenges posed by complex geometric components under different temperature conditions, this research employs finite element simulation to expand the limited experimental dataset and utilizes these data to further guide and optimize the MLHD_DBO_BP model. Test results indicate that the proposed MLHD_DBO_BP model significantly outperforms the traditional finite element method (FEM) and other neural network models in terms of fatigue life prediction performance. This research demonstrates the effectiveness of machine learning models that combine experimental and simulation data in predicting the low‐cycle fatigue life of Ti‐6Al‐4V alloy.
Ultrasonicated omega‐3‐enriched skipjack tuna eyeball oil nanoliposome: preparation, characterisation, and fortification in milk
Authors: Kurniawan Marcella Octavina , Mittal Ajay , Benjakul Soottawat , Singh Avtar 
Published: August 2024

SummaryNanoliposomes (NL) containing different levels (1%, 2%, and 5%; w/w) of EPA/DHA‐enriched oil (n3FAO) from skipjack tuna eyeballs were prepared using 1%, 2.5%, and 5% (w/v) of soy phosphatidylcholine lecithin (SL) as a wall material. Then, the impact of ultrasonication at different amplitudes (40% and 50%) and sonication time (5 and 10 min) on encapsulation efficiency (EE) of selected NL was also investigated. NLs prepared without ultrasonication treatment using 2.5% SL and 2% n3FAO (WU‐NL) showed the highest EE (88%) than the remaining concentrations. When ultrasound at 40% amplitude for 5 min was applied, NLs (US‐NL) having the maximum EE of 98% were achieved. Ultrasonication employed at all conditions showed increased particle size (31.6–67.2 nm) than the WU‐NL (22.8 nm). Microstructure suggested the formation of particles with smooth surfaces and homogenous distribution. When NL powders were incorporated into the fresh cow milk at various levels (2.5% and 5.0%; w/v), likeness for aroma, mouthfeel, taste, and aftertaste slightly decreased, especially at higher levels (5%) for all samples. Nevertheless, the likeness score remained within acceptable levels (≥5.0). The fatty acid profile of the milk fortified with 2.5% (w/w) NLs showed a significant increase in polyunsaturated fatty acids (PUFAs), including EPA and DHA. Therefore, the findings indicated that ultrasonication improved the EE of liposomes, which could be successfully incorporated into milk and other food items with a lower content of PUFAs, boosting their nutritional profile while maintaining their taste and sensory attributes.
Composition of sesame hull oil and its effects on flavour and quality of sesame oil
Authors: Wang Rui , Guo Bing‐Xin , Li Xiao‐Yu , Peng Jin‐Qiao , Liu Yi‐Tong , Chang Yun‐Long , Liu Hua‐Min , Wei Wen‐Xing , Wen Xin‐Yu , Zhang Hong‐Yu , Liu Hong‐Wei 
Published: August 2024

SummaryIn this study, sesame hull oil (SHO) was extracted to characterise its composition. SHO was heated to determine the volatiles and their effect on the quality of cold‐pressed dehulled sesame oil (SO). Seventeen fatty acids, four lignans (1088.65 mg/100 g), tocopherols (284.17 mg/100 g) mainly in the γ‐form, and sterol (1722.16 mg/100 g, 4.67 times more than in sesame kernel oil) were detected in SHO. After heating, the volatiles found in SHO were mainly aldehydes and acids, represented by hexanal (fatty, green aroma) and 3‐methyl‐butanoic acid (fatty, rancid aroma), respectively. The acid value, peroxide value, anisidine value, and turbidity of SO increased significantly after adding SHO, and the scavenging ability of 2,2‐diphenyl‐1‐picrylhydrazyl (DPPH) was enhanced. The oxidation induction times of SO with the addition of SHO ranged from 8.93 to 9.53 h. The present study provides information about SHO and a new direction for the utilisation of sesame hulls.
Postbiotic emissaries: a comprehensive review on the bioprospecting and production of bioactive compounds by Enterococcus species
Authors: Chaudhary Arati , Prajapati Nidhi , Prajapati Ansh , Singh Sachidanand , Joshi Madhvi , Prajapati Dharmendra , Patani Anil , Sahoo Dipak Kumar , Patel Ashish 
Published: August 2024

SummaryEnterococcus species have been acknowledged for their diverse metabolic capabilities, resulting in a wide array of bioactive compounds that show promise for therapeutic use. This article presents a thorough examination of the exploration and synthesis of bioactive compounds by Enterococcus species. It encompasses the taxonomy, natural habitat, and significance in the biotechnology of Enterococcus, emphasising the various bioactive compounds it produces, including antibacterial, immunomodulatory, and antioxidant agents. Strategies for exploring potential bioactivities, encompassing isolation methodologies and screening techniques, are discussed. The biotechnological synthesis of bioactive compounds derived from Enterococcus via fermentation processes, optimisation approaches, and scaling methodologies is expounded. Moreover, the utilisation of these bioactive compounds in functional foods, pharmaceuticals, and agriculture, alongside considerations of safety and regulatory aspects, is examined. The review concludes with future perspectives and challenges in the field of Enterococcus‐derived bioactive compounds.
Flexible Multivariate Mixture Models: A Comprehensive Approach for Modeling Mixtures of Non‐Identical Distributions
Authors: Pal Samyajoy , Heumann Christian 
Published: August 2024

SummaryThe mixture models are widely used to analyze data with cluster structures and the mixture of Gaussians is most common in practical applications. The use of mixtures involving other multivariate distributions, like the multivariate skew normal and multivariate generalised hyperbolic, is also found in the literature. However, in all such cases, only the mixtures of identical distributions are used to form a mixture model. We present an innovative and versatile approach for constructing mixture models involving identical and non‐identical distributions combined in all conceivable permutations (e.g. a mixture of multivariate skew normal and multivariate generalised hyperbolic). We also establish any conventional mixture model as a distinctive particular case of our proposed framework. The practical efficacy of our model is shown through its application to both simulated and real‐world data sets. Our comprehensive and flexible model excels at recognising inherent patterns and accurately estimating parameters.
Patient safety incident reporting software: A cross‐sectional survey of nurses and other users' perspectives
Authors: Koskiniemi Saija , Syyrilä Tiina , Hämeen‐Anttila Katri , Mikkonen Santtu , Manias Elizabeth , Rafferty Anne Marie , Franklin Bryony Dean , Härkänen Marja 
Published: August 2024

AbstractAimTo investigate nurses' and other users' perceptions and knowledge regarding patient safety incident reporting software and incident reporting.DesignA cross‐sectional online survey.MethodsThe survey, ‘The Users' Perceptions of Patient Safety Incident Reporting Software’, was developed and used for data collection January–February 2024. We aimed to invite all potential users of reporting software in two wellbeing service counties in Finland to participate in the survey. Potential users (reporters/handlers/others) were nurses, other health professionals and employees. Satisfaction was classified as dissatisfied, neutral, or satisfied. The association between overall satisfaction and demographics was tested using cross‐tabulation and a Chi‐square test.ResultsThe completion rate was 54% (n = 755). Some respondents (n = 25) had never used reporting software, most often due to no perceived need to report, although their average work experience was 15 years. Of other respondents (n = 730), mostly nurses (n = 432), under half agreed that the software was quick to use and easy to navigate. The biggest dissatisfaction was with the report processing features. Over a fifth did not trust that reporting was anonymous. Training and frequency of using the software were associated with overall satisfaction.ConclusionReporting software has not reached its full potential and needs development. Report handling is essential for shared learning; however, the processing features require the most improvements. Users' perceptions must be considered when developing reporting software and processes.ImpactIncident reporting software usability is central to reporting, but nurses' and other users' perceptions of software are poorly understood. This survey shows weaknesses in reporting software and emphasizes the importance of training. The survey can contribute to paying more attention to organizing training, getting users to participate in software development, and deepening knowledge of issues in reporting software. Making the needed improvements could improve patient safety.Reporting MethodThe STROBE Checklist (Supplement‐S1).Patient or Public ContributionNo Patient or Public Contribution.
Midwives' support for parents following stillbirth: How they practise and resources they need from a phenomenological perspective
Authors: de los Ángeles Linares‐Gallego María , Martínez‐Linares Jose Manuel , del Mar Moreno‐Ávila Isabel , Cortés‐Martín Jonathan 
Published: August 2024

AbstractAimTo explore the perceptions and experiences of midwives caring for couples who experience a stillbirth.DesignQualitative study based on Gadamer's hermeneutic phenomenology.MethodsThis study was conducted with midwives (n = 18) at the birth unit of a third‐level public hospital in Jaén (Spain) in 2023. Personal semi‐structured interviews were recorded in audio for later transcription by two researchers following steps described by Fleming.ResultsTwo themes were identified as important aspects of the practise of midwives in a situation of the birth of a stillborn child: (1) the importance of each action of the midwife, and (2) the availability of resources determines the care provided.ConclusionsHaving a stillbirth is a very complex experience, in which the psychological support and human and material resources involved are the basic tool for the care of these families. Acknowledging limitations of the available resources, the assistance and care provided by midwives are in line with the clinical practice guidelines, which can have an emotional impact on them.Implications for the Profession and/or Patient CareThe care to be provided in stillbirth requires appropriate human and material resources for these families. Midwifery and nursing professionals are in a unique position for acting in cases of families with a stillbirth, updated protocols and, in general, the coordination of the different agents involved within the healthcare system.What Problem Did the Study Address?The midwives´ experiences in cases which end with the delivery of a stillborn.What Were the Main Findings?Each action of the midwife is as important as the availability of resources to offer the most appropriate care.Where and on Whom Will the Research have an Impact?In each woman who receives the care of a midwife who attends the birth of a stillborn.Reporting MethodCOREQ checklist.Patient or Public ContributionNo patient or public contribution occurred for this study as this research focused on exploring staffs' perspectives from the specific viewpoint of their personal experience.
Forward contracting and the endogenous activity of heterogeneous firms
Authors: Mitraille Sébastien , Thille Henry 
Published: August 2024

AbstractForward contracting in an ‐firm quantity‐setting oligopoly with heterogeneous costs introduces the possibility that relatively efficient firms deter the activity of inefficient rivals by reducing their margins. The equilibrium number of firms producing positive quantities can be any of depending on the level of demand relative to firm‐specific activity thresholds, with more firms active at higher demand levels. If only one firm is active, the Bertrand outcome is obtained. This potential reduction of the number of active firms may lessen the procompetitive effect of forward sales, but does not eliminate it entirely. We explore the competition policy implications of the endogenous activity of firms, in particular for merger analysis.
The impact of energy‐based devices on sebum in acne vulgaris: A systematic review
Authors: Jaalouk Dana , Pulumati Anika , Algarin Yanci A. , Humeda Jasmine , Goldberg David J. 
Published: August 2024

AbstractBackgroundAcne vulgaris (AV) is a widespread inflammatory skin condition associated with increased sebum production, abnormal keratinization, bacterial overgrowth, and inflammation. Overactive sebaceous glands (SGs) produce excess sebum, promote Cutibacterium acnes growth, and affect acne development. Energy‐based treatments (EBDs), including light therapy, photodynamic therapy (PDT), lasers, and radiofrequency (RF) devices, have emerged as effective treatment options. As the use of EBDs becomes more widespread, it is imperative to understand their effects on skin parameters, such as sebum, in AV.MethodsSearches were conducted in Embase, PubMed, Web of Science, and the Cochrane Library. The studies included were randomized and nonrandomized trials on facial AV that used EBDs and featured objective casual sebum level (CSL) measurements via Sebumeter. Data synthesis involved percentage reductions in CSL at follow‐ups compared to baseline.ResultsTwenty‐three studies were analyzed. PDT and RF consistently reduced CSL by 30%–40% and 30%–35%, respectively. Laser therapy showed lesser reductions, whereas light therapy varied significantly and studies had a high risk of bias. All EBD therapies were more effective than no treatment and PDT was superior to light monotherapy. Laser therapy combined with fractional microneedling radiofrequency (FMR) or as a standalone was more effective than laser alone.ConclusionNoninvasive sebum measurement provides valuable insights into AV treatment efficacy. PDT, lasers, especially the 1450‐nm diode laser, and FMR are promising for reducing sebum. Standardization of measurement techniques and further research are vital for enhancing treatment personalization, reducing side effects, and improving AV management.
Variation in diagnostic methods, criteria, and treatment for chronic endometritis: A nationwide survey in Japan
Authors: Jwa Seung Chik , Kuroda Keiji , Shirasawa Hiromitsu , Harada Miyuki , Osuga Yutaka , Yamada Mitsutoshi 
Published: August 2024

AbstractAimTo investigate variation in the diagnosis and treatment of chronic endometritis (CE) at the national level in Japan.MethodsWe performed a nationwide survey targeting all assisted reproductive technology (ART) facilities across Japan between 2021 and 2022. Diagnostic methods, criteria, and first‐ and second‐line treatment protocols for CE were collected via a questionnaire.ResultsAmong 616 ART facilities, 437 responded to the survey (response rate: 70.9%) of which 339 (77.6%) implemented diagnosis and treatment of CE. In the diagnosis of CE, 214 (63.1%) facilities used CD138 immunohistochemical staining of endometrial tissue, while hysteroscopy was the most frequently used as an adjunct diagnostic method (241 facilities, 71.1%). The most frequent cutoff value of CD138‐positive cells for diagnosing CE was 3–5 cells/20 high‐power fields (50%), but 7.9% (17 facilities) and 5.1% (11 facilities) used cutoff values of 1 and 2 cells, respectively. The most common first‐ and second‐line treatment methods were doxycycline (210 facilities, 61.9%) and ciprofloxacin + metronidazole (164 facilities, 48.0%), respectively.ConclusionsThere is considerable variation in the number of CD138‐positive cells used for diagnosing CE. Establishing unified diagnostic criteria and therapeutic methods for CE is essential to provide standardized medicine for CE at the national level.
The effect of antibiotic premedication on postoperative complications following dental extractions
Authors: McGregor Jessina C. , Wilson Geneva M. , Gibson Gretchen , Jurasic M. Marianne , Evans Charlesnika T. , Suda Katie J. 
Published: August 2024

AbstractObjectivesWe aimed to evaluate the association between antibiotic prophylaxis and adverse outcomes following tooth extraction within the Veterans Affairs Healthcare System.MethodsWe conducted a retrospective cohort study of patients undergoing dental extractions in 2015–2019. The primary exposure was antibiotic prophylaxis. The primary outcome was post‐extraction complication within 7 days (e.g., alveolar osteitis and surgical site infection); the secondary outcome was subsequent medical care relating to a post‐extraction oral complication within 7 days. Multivariable logistic regression models assessed the independent effect of antibiotic prophylaxis on each outcome.ResultsOf 385,880 visits with a dental extraction, 122,810 (31.8%) received antibiotic prophylaxis. Overall, 3387 (0.9%) experienced a post‐extraction complication and 350 (0.09%) received medical care relating to a post‐extraction oral complication within 7 days. In multivariable regression, diabetes was a statistically significant (p = 0.01) effect modifier of the association between antibiotic prophylaxis and post‐extraction complication. Among visits for patients without diabetes, antibiotic prophylaxis was significantly associated with an increased odds of post‐extraction complication (odds ratio [OR] = 1.25, 95% confidence interval [CI]: 1.13–1.38), but among visits for patients with diabetes no significant effect was observed (OR = 1.03, 95% CI: 0.92–1.15). Antibiotic prophylaxis was not significantly associated with post‐extraction medical care (OR = 1.04; 95% CI: 0.83–1.30).ConclusionsIn this large retrospective cohort, we observed no significant protective effect of antibiotic prophylaxis on post‐extraction complications or subsequent medical care utilization in a setting with low complication rates. These data suggest that use of antibiotic prophylaxis in similar settings may need to be re‐evaluated to minimize unnecessary antibiotic use.