bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Role of Smoking and Gingival Crevicular Fluid Markers on Coronally Advanced Flap Outcomes
Authors: Kaval Başak , Renaud Diane E. , Scott David A. , Buduneli Nurcan 
Published: May 2013

Background: This study evaluates possible effects of smoking on the following: 1) biochemical content in gingival crevicular fluid (GCF) samples from sites of gingival recession and saliva; and 2) clinical outcomes of coronally advanced flap (CAF) for root coverage.Methods: Eighteen defects in 15 patients were included in each of the smoker and non‐smoker groups. Baseline cotinine, basic fibroblast growth factor, vascular endothelial growth factor, platelet‐derived growth factor, interleukin (IL)‐8, IL‐10, IL‐12, tumor necrosis factor‐α, matrix metalloproteinase (MMP)‐8, MMP‐9, and plasminogen activator inhibitor‐1 levels were determined in GCF and saliva samples. CAF with microsurgery technique was applied. Plaque index, papilla bleeding index, recession depth (RD), recession width (RW), and root surface area were evaluated at baseline and postoperative months 1, 3, and 6. Probing depth, clinical attachment level (CAL), and keratinized gingival width (KGW) was recorded at baseline and month 6. Percentage of root coverage and complete root coverage were calculated at postoperative months 1, 3, and 6.Results: All biochemical parameters were similar in the two groups apart from the definite difference in salivary cotinine concentrations (P = 0.000). Compared with the baseline values, RD, RW, CAL, and root surface area decreased, and KGW increased, with no significant difference between the study groups. CAL gain, percentage of root coverage, and complete root‐coverage rates were similar in the study groups.Conclusion: Similar baseline biochemical data and comparably high success rates of root coverage with CAF in systemically and periodontally healthy smokers versus non‐smokers suggest lack of adverse effects of smoking on clinical outcomes.
Cardiorenal Syndrome
Authors: Kazory Amir 
Published: May 2013

Summary
Heart failure remains the leading cause of hospitalization in older patients and is considered a growing public health problem with a significant financial burden on the health care system. The suboptimal efficacy and safety profile of diuretic-based therapeutic regimens coupled with unsatisfactory results of the studies on novel pharmacologic agents have positioned ultrafiltration on the forefront as an appealing therapeutic option for patients with acute decompensated heart failure (ADHF). In recent years, substantial interest in the use of ultrafiltration has been generated due to the advent of dedicated portable devices and promising results of trials focusing both on mechanistic and clinical aspects of this therapeutic modality. This article briefly reviews the proposed benefits of ultrafiltration therapy in the setting of ADHF and summarizes the major findings of the currently available studies in this field. The results of more recent trials on cardiorenal syndrome that present a counterpoint to previous observations and highlight certain limitations of ultrafiltration therapy are then discussed, followed by identification of major challenges and unanswered questions that could potentially hinder its more widespread use. Future studies are warranted to shed light on less well characterized aspects of ultrafiltration therapy and to further define its role in ADHF and cardiorenal syndrome.
Doxycycline concentration over time after storage in a compounded veterinary preparation
Authors: Papich Mark G. , Davidson Gigi S. , Fortier Lisa A. 
Published: May 2013

Abstract
Objective—To determine the concentration of doxycycline compounded from doxycycline hyclate tablets into liquid formulations for oral administration in veterinary species and stored for 28 days.
Design—Evaluation study.
Sample—Doxycycline hyclate tablets (100 mg) crushed and mixed with a 50:50 mixture of syrup and suspension vehicles for oral administration to produce 3 batches each of 2 doxycycline formulations: 33.3 and 166.7 mg/mL.
Procedures—Formulations were stored, protected from light, at room temperature (22° to 26°C [71.6° to 78.8°F]) and at a controlled cold temperature (refrigerated 2° to 8°C [35.6° to 46.4°F]). Doxycycline was extracted from the formulations, and concentration was measured by high-pressure liquid chromatography on days 0 (date of preparation), 1, 4, 7, 14, 21, and 28. Concentrations were compared with those of a US Pharmacopeial Convention reference standard. Formulation quality at each point was also assessed through color change, formulation consistency, and suspension uniformity.
Results—On days 0, 1, 4, and 7, the concentration of each formulation was within 90% to 110% of the reference standard (range, 93% to 109%), which was deemed acceptable. However, doxycycline concentrations had decreased dramatically by day 14 and remained low for the duration of the study period. Doxycycline concentrations on days 14, 21, and 28 were all < 20% (range, 14% to 18%) of the reference standard, and the quality of the formulations decreased as well. No effect of storage temperatures on doxycycline concentration was identified.
Conclusions and Clinical Relevance—The concentration of doxycycline, compounded from commercial tablets in the vehicles evaluated to yield doses of 33.3 and 166.7 mg/mL, cannot be assured beyond 7 days.
Evaluation of risk factors for outcome associated with adrenal gland tumors with or without invasion of the caudal vena cava and treated via adrenalectomy in dogs: 86 cases (1993–2009)
Authors: Barrera Jessica S. , Bernard Fabrice , Ehrhart E. J. , Withrow Stephen J. , Monnet Eric 
Published: May 2013

Abstract
Objective—To evaluate risk factors for outcome for dogs with adrenal gland tumors with or without invasion of the caudal vena cava treated via adrenalectomy.
Design—Retrospective study.
Animals—86 dogs that underwent adrenalectomy for treatment of adrenal gland tumors.
Procedures—Medical records of dogs that underwent adrenalectomy for treatment of an adrenal gland tumor from 1993 to 2009 were reviewed; data collected including signalment, clinical signs, diagnostic test findings, treatments prior to surgery, findings at surgery including additional procedures performed and extent of caudal vena caval invasion (local invasion [caudal to the hepatic portion of the vena cava] or extensive invasion [cranial to the hepatic portion of the vena cava]), procedures performed during surgery, histopathologic diagnosis, perioperative complications, follow-up data, and necropsy findings.
Results—Of the 86 dogs, 14 had adenomas, 45 had adrenocortical carcinomas, and 27 had pheochromocytomas. Fourteen dogs had invasion of the caudal vena cava; of these tumors, 7 were locally invasive and 7 were extensively invasive. Risk factors for poor short-term survival (death within 14 days following surgery) were vena caval invasion, extent of invasion, pheochromocytoma, intraoperative transfusion, and postoperative factors including disseminated intravascular coagulation, pancreatitis, hypotension, hypoxemia, and renal failure. Multivariate analysis of risk factors for poor short-term survival revealed that extensive invasion was the most important factor. Regardless of extent of invasion or tumor type, long-term survival was possible.
Conclusions and Clinical Relevance—Invasion of the caudal vena cava, particularly tumor thrombus extension beyond the hepatic hilus, was associated with a higher postoperative mortality rate, but did not affect long-term prognosis in dogs undergoing adrenalectomy because of an adrenal gland tumor.
Unilateral laryngeal paralysis subsequent to surgical ligation of a patent ductus arteriosus in an 8-week-old domestic shorthair cat
Authors: Adamovich-Rippe Krista N. , Steffey Michele A. , Ybarra Winnie L. , Johnson Lynelle R. 
Published: May 2013

Abstract
Case Description—An 8-week-old female domestic shorthair cat was treated for patent ductus arteriosus (PDA) with surgical ligation. Seven weeks postoperatively, the cat was evaluated because of increased upper respiratory noise, inspiratory stridor, wheezing, and episodes of intermittent open-mouth breathing that had developed 1 week following the surgical ligation.
Clinical Findings—The cat was sedated, and examination of the larynx revealed left-sided laryngeal paralysis.
Treatment and Outcome—At the time left-sided laryngeal paralysis was diagnosed, the clinical signs of laryngeal dysfunction were not considered severe enough to warrant surgical intervention. No treatment was administered, and the owner monitored the cat for respiratory distress and worsening of clinical signs for an additional 5 months. During those 5 months, the clinical signs improved but persisted. Seven months after PDA ligation, the cat was again sedated and the larynx examined. The examination revealed persistent left arytenoid dysfunction, which was believed to be the result of permanent damage to the recurrent laryngeal nerve that was sustained during the surgical ligation of the PDA. The owner was counseled about surgical and medical treatment options for laryngeal paralysis but elected to forego treatment at that time.
Clinical Relevance—Unilateral laryngeal paralysis caused by iatrogenic damage to the recurrent laryngeal nerve is a potential complication subsequent to surgical ligation of a PDA. The frequency of iatrogenically induced laryngeal paralysis is likely underestimated in small animal patients. Laryngoscopy should be performed in any small animal with a history of PDA attenuation and clinical signs of respiratory tract disease.
Management factors associated with veterinary usage by organic and conventional dairy farms
Authors: Richert Roxann M. , Cicconi Kellie M. , Gamroth Mike J. , Schukken Ynte H. , Stiglbauer Katie E. , Ruegg Pamela L. 
Published: May 2013

Abstract
Objective—To identify management factors associated with veterinary usage by organic and conventional dairy farms.
Design—Prospective case-control study.
Sample—292 farms.
Procedures—Organic farms in New York, Oregon, and Wisconsin were matched to conventional farms on the basis of location and herd size. During a single herd visit, a questionnaire was administered, information about animal disease incidence and number of veterinarian visits in the preceding 60 days was collected, and forms to record similar information during the 60 days after the visit were left for the herd manager to complete. For analysis, conventional herds were classified as either grazing or nongrazing. Multiple correspondence analysis was used to assess relationships among management factors and selected outcomes for frequency of veterinary usage.
Results—Intensive management practices were closely associated with frequent veterinary usage. Generally, organic management practices were associated with less frequent veterinary usage than were conventional management practices. Conventional grazing practices were associated with intermediate veterinary usage (more than organic practices but less than intensive practices), whereas conventional nongrazing practices were associated with frequent veterinary usage. Cost of routinely scheduled veterinarian visits/45 kg (100 lb) of milk produced/y was greater for small farms than that for large farms.
Conclusions and Clinical Relevance—Results suggested that management intensiveness was more closely associated with frequency of veterinary usage than was organic status; therefore, veterinarians should characterize farms by factors other than organic status when investigating which farms are most likely to use their services. Economic factors substantially affected routine veterinary usage on small farms.
Evaluation of impurities in simvastatin drug products with the use of FT-IR spectroscopy and selected chemometric techniques
Authors: Kupcewicz Bogumiła , Ronowicz Joanna , Balcerowska-Czerniak Grażyna , Walasek Andrzej , Budzisz Elżbieta 
Published: May 2013

Abstract
In the present study a reversed phase high performance liquid chromatography (RP-HPLC) method with diode array detector (DAD) at room temperature was used for obtaining impurity profiles of 20 drug products containing simvastatin as an active substance. Fourier-transform infrared spectroscopy (FT-IR) was carried out to obtain absorption spectra of samples. The partial least squares (PLS) model was built to predict the relative content of lovastatin, the main impurity of simvastatin, and sum of statin-like impurities. In order to build the PLS model, peak areas obtained from HPLC chromatograms were related to FT-IR spectra of drugs. The PLS model based on signal normal variate and orthogonal signal correction (SNV+OSC) transformed FT-IR spectra was able to predict the content of drug impurities in real samples with a good prediction ability (R2 &gt; 0.95).
Spectroscopic study of associated systems formed between water-soluble cationic porphyrins or their copper (II) complexes and nucleic building blocks
Authors: Makarska-Bialokoz Magdalena 
Published: May 2013

Abstract
The association process between two water soluble cationic porphyrins, 5,10,15,20-tetrakis[4-(trimethyl-ammonio)phenyl]-21H,23H-porphine tetra-p-tosylate (H2TTMePP) and 5,10,15,20-tetrakis(1-methyl-4-pyridyl)-21H,23H-porphine tetra-p-tosylate (H2TMePyP), as well as their Cu (II) complexes, with five series of nucleic agents has been studied using UV-VIS spectroscopy in aqueous solutions. During the titration with nucleic compounds the bathochromic effect of porphyrins absorption spectra can be observed as well as the hypochromicity of the Soret maximum. The association constants were calculated using a curve-fitting procedure (KAC of the order of magnitude of 103–105 mol−1). It has been shown that the interactions of H2TTMePP with nucleic agents are much stronger than interactions of H2TMePyP, which is most likely related to the kind and the size of the porphyrin substituent groups partaking in the process of stacking. The strength of the observed associated systems increases generally in a series: nucleic base
Cobalt electrodeposition onto polycrystalline gold from ammoniacal solutions
Authors: Mendoza-Huizar Luis , Rios-Reyes Clara 
Published: May 2013

Abstract
In the present work, the cobalt electrodeposition onto polycrystalline gold electrodes from aqueous solutions containing 0.01M CoSO4 + 1 M (NH4)2SO4 at pH=7 was analyzed. Linear voltammetry results suggested a change in the kinetic of the cobalt electrodeposition. In all cases, the nucleation rate (A), the number of active nucleation sites (N 0) and the saturation number of nuclei (N s ) values were potential dependent. The calculated Gibbs free energy (ΔG) for this system was 1.88×10−20 J nuclei−1 and the transfer coefficient for the Hydrogen Electroreduction Reaction (HER) was 0.47.
Individual-Level Responsiveness of the Original and Short-Form Postural Assessment Scale for Stroke Patients
Authors: Hsueh I-Ping , Chen Kuan-Lin , Chou Yeh-Tai , Wang Yen-Ho , Hsieh Ching-Lin 
Published: May 2013

BackgroundThe group-level responsiveness of the Postural Assessment Scale for Stroke Patients (PASS) is similar to that of the short-form PASS (SFPASS). This result is counterintuitive because the PASS has more items (12) and response levels (4) than does the SFPASS (5 items and 3 response levels).ObjectiveThe purpose of this study was to compare individual-level responsiveness between both measures to determine whether the SFPASS can detect change with as much sensitivity as the PASS.Study Design and SettingTwo hundred fifty-one patients were assessed using the PASS at 14 and 30 days after stroke onset in a medical center.MethodsThe SFPASS scores were calculated from the patients’ responses on the PASS. Individual-level responsiveness was calculated on the basis of the value of minimal detectable change (MDC). If a patient’s change score was greater than the MDC of the PASS or SFPASS, his or her improvement was considered significant. The difference in the number of patients scoring greater than the MDC and the units of MDC (the MDC ratio) improved by the patients on both measures was examined.ResultsFifty-three percent of the patients scored greater than the MDC of the PASS, whereas 43.0% of the patients scored greater than the MDC of the SFPASS. The difference was significant. The mean (±SD) MDC ratio of the PASS (1.8±1.7) was significantly higher than that of the SFPASS (1.2±1.3).LimitationsThe scores of the SFPASS were retrieved from those of the PASS, which limits the generalization of our findings.ConclusionsThe PASS has better individual-level responsiveness than does the SFPASS. To comprehensively report effects of clinical trials, future studies using the PASS should report the individual-level effect (eg, number of patients scoring greater than the MDC).
‘Implicated by the truth’
Authors: Connelly Karen , Kamboureli Smaro , McGregor Hannah 
Published: May 2013

abstract Karen Connelly’s poetry and prose has dealt extensively with her experience of living abroad and writing about foreign places – notably Thailand, Burma, France, Spain, and Greece. In this interview, she discusses how learning a foreign language offers her a point of entry into a new culture and transforms her sense of self as well as how her books – especially Touch the Dragon, One Room in a Castle, The Lizard Cage, and Burmese Lessons – engage with concepts of the foreign and the fraughtness of empathy.
Canadian Female Gothic on the Foreign Border: Margaret Atwood’sBodily Harmand Karen Connelly’sBurmese Lessons
Authors: Goldman Marlene 
Published: May 2013

abstractMy essay analyzes why and how Atwood’s Bodily Harm and Connelly’s Burmese Lessons forge an identification of female and Canadian identity with the heroine of the Female Gothic who is eternally in need of rescue. In both works, empathy for the ‘other’ is mediated by the narratives’ fidelity to the Female Gothic which informs their depictions of the male foreigner as the seductive, menacing other. Although Bodily Harm’s and Burmese Lessons’s construction of white female identity as traumatized and silenced is ultimately rejected, both narratives adhere to the Gothic’s emphasis on the heroines’ battles against victimization and patriarchal control. Whereas Bodily Harm follows the logic of the Gothic, Burmese Lessons outlines an alternative biopolitical engagement with the foreign based on a recognition rather than a disavowal of the nonhuman animal within the human – a recognition that, while grounded in the Gothic, exceeds its opposition between powerful men and helpless women.
‘History’s Pulse Measured with Another Hand’: Precarity Archives and Translocal Citizen Witness in Dionne Brand’sInventory
Authors: Vellino Brenda Carr 
Published: May 2013

abstractDionne Brand’s long poem Inventory (2006) calls for recognition of intersecting sites of embodied vulnerability within the state security regimes that render Arab bodies as collateral damage and the deportation regimes that produce undocumented workers, refugees, and asylum seekers as ‘the citizen’s other.’ Brand’s central strategy is the creation of juxtaposed precarity archives of disregarded bodies subject to violent death in Iraqi war zones and in transnational deportation zones. Foregrounding the meditated witness to international atrocities, Brand constructs a tenuous position of ethical accounting through four related strategies: creation of a post-identitarian yet embodied poetic subjectivity; interrogation of distanced witness passivity through the stance of translocal citizenship; mapping cross connections between zones of precarization; and producing affective intimacy based in the material vulnerability of the body as the foci for ‘ethically oppositional mourning’ (Spargo).
‘Throw yourself into the deep end’
Authors: Gibb Camilla , Kamboureli Smaro , McGregor Hannah 
Published: May 2013

abstract Camilla Gibb discusses how and why her creative impulse finds its inspiration elsewhere – in Ethiopia and England for her novel Sweetness in the Belly and Vietnam for her novel The Beauty of the Humanity Movement – the limits of the cultural appropriation debate, and the relationship between her training as anthropologist and her fiction writing.
Gendered Colonial Complicity and Postcolonial Desire: Daphne Marlatt’s ‘In the Month of Hungry Ghosts’
Authors: Beverley Andrea 
Published: May 2013

abstract First published in The Capilano Review in 1979, Daphne Marlatt’s ‘In the Month of Hungry Ghosts’ is a multigeneric text that emerged out of a trip that Marlatt took to visit her childhood home in Penang, Malaysia. This essay focuses on the narrator’s relationship to her surroundings in Penang, the representation of her memsahib mother, and the narrator’s desire to reconnect with her childhood caretaker. The narrator positions herself in relation to these two women to grapple with the legacies of the class and gender dynamics of her childhood household. She experiences a disquieting sense of colonial complicity as well as an anticolonial, feminist desire to articulate that complicity and to cultivate relationships that move beyond colonial scripts.
Correlation between magnetoencephalography-based “clusterectomy” and postoperative seizure freedom
Authors: Vadera Sumeet , Jehi Lara , Burgess Richard C. , Shea Katherine , Alexopoulos Andreas V. , Mosher John , Gonzalez-Martinez Jorge , Bingaman William 
Published: May 2013

Object
During the presurgical evaluation of patients with medically intractable focal epilepsy, a variety of noninvasive studies are performed to localize the hypothetical epileptogenic zone and guide the resection. Magnetoencephalography (MEG) is becoming increasingly used in the clinical realm for this purpose. No investigators have previously reported on coregisteration of MEG clusters with postoperative resection cavities to evaluate whether complete “clusterectomy” (resection of the area associated with MEG clusters) was performed or to compare these findings with postoperative seizure-free outcomes.

Methods
The authors retrospectively reviewed the charts and imaging studies of 65 patients undergoing MEG followed by resective epilepsy surgery from 2009 until 2012 at the Cleveland Clinic. Preoperative MEG studies were fused with postoperative MRI studies to evaluate whether clusters were within the resected area. These data were then correlated with postoperative seizure freedom.

Results
Sixty-five patients were included in this study. The average duration of follow-up was 13.9 months, the mean age at surgery was 23.1 years, and the mean duration of epilepsy was 13.7 years. In 30 patients, the main cluster was located completely within the resection cavity, in 28 it was completely outside the resection cavity, and in 7 it was partially within the resection cavity. Seventy-four percent of patients were seizure free at 12 months after surgery, and this rate decreased to 60% at 24 months. Improved likelihood of seizure freedom was seen with complete clusterectomy in patients with localization outside the temporal lobe (extra–temporal lobe epilepsy) (p = 0.04).

Conclusions
In patients with preoperative MEG studies that show clusters in surgically accessible areas outside the temporal lobe, we suggest aggressive resection to improve the chances for seizure freedom. When the cluster is found within the temporal lobe, further diagnostic testing may be required to better localize the epileptogenic zone.