bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Impact of Digital Ecosystems on the Financial Management Efficiency in State Institutions
Authors: YATSUKH Olena , CHYHYRYNSKYI Artem , PURHANI Safar Hasan , BULHAKOVA Olena , DURMAN Mykola 
Published: June 2024

Purpose: Digital ecosystems are a key driver of development at the current stage, in particular, in state institutions. Increasing efficiency of financial management through digitalization in the public sector is one of the key directions. The aim of the study is to determine the impact of digital ecosystems on the results of financial management in Ukrainian and Azerbaijani public institutions.
Methodology: The research employed the methodological tools of regression and correlation analysis, as well as descriptive statistics to determine the impact of digitalization on the effectiveness of financial management of institutions. The application of the least squares method revealed a statistically significant positive effect of digital technology spending (β1 = 0.0528, p = 0.010) on management efficiency, while other variables showed insignificant or negative effects. The model explains 43.6% of the variation in the dependent variable, with R-squared = 0.436 and Adjusted R-squared = 0.285.
Findings: Correlation analysis confirmed a strong positive relationship (r=0.58) between digitization costs and management efficiency. The article provides practical recommendations for optimizing the implementation of digital technologies in the management of public finances, including the development of electronic services and increasing the level of digital literacy.
Originality: Further research in the chosen direction will be focused on the formation and implementation of a system of key indicators of the effectiveness of digital ecosystems from the perspective of the efficiency of financial management in public institutions of Ukraine and Azerbaijan.
Analysis Of Clerodendrum inerme Plant Compounds as Anti Diabetes Mellitus Through Network Pharmacology Approach
Authors: Jamil Ahmad Shobrun , Hilmy Fauzan 
Published: June 2024

Background: Diabetes mellitus prevalence in Indonesia has surged. In 2021, an estimated 19.5 million people had diabetes, with a 10.6% age-adjusted prevalence. Projections indicate around 9.5 million cases by 2024. Diabetes medications, such as metformin, are commonly used, although these medications have adverse effects. A common choice for chronic diseases like DM is the use of natural medications. A plant known as Clerodendrum inerme has the potential to alleviate diabetes, but little is known about its molecular mechanismsObjective: The purpose of this study was to explore the content of Clerodendrum inerme plant compounds and their potential for cases of Diabetes Mellitus.Methods: The KNApSAcK was used to conduct an analysis of plant parts of Clerodendrum inerme to seek out chemicals present in plants. A screening was done to find compounds by estimating Absorption, Distribution, Metabolism, and Excretion (ADME) parameters using the canonical Simplified molecular-input line-entry system (SMILES) on the SwissADME. On the SwissTargetPrediction tool, predictions of target proteins from compounds that pass screening are connected to various probable proteins. utilising the String-db to show the network between target proteins and associated diseasesResults: The Clerodendrum inerme consist of 24 different compound. The 24 compounds were screened, and the results showed that 4 of them, specifically (Z)-3-Hexenyl beta-D-glucopyranoside, Rhodioloside, Sammangaoside B, and Clerodermic acid, had the potential to be developed into therapeutic agent. The compound are then analysed in order to find the protein target associated with diabetes mellitus and predict its networks. The findings indicate that multiple target proteins, including GSK3B, PPARG, DPP4, and STAT3, are connected to diabetes mellitus.Conclusion: It has been shown that (Z)-3-Hexenyl beta-D-glucopyranoside, or clerodermic acid, is able to attach to the proteins GSK3B, PPARG, DPP4, and STAT3, which are all linked to diabetes mellitus.
Population genetics of Todarodes pacificus (Cephalopoda: Ommastrephidae) in the northwest Pacific Ocean via GBS sequencing
Authors: Liu Yang , Hu Xingxing , Lu Huajie , Liu Yimeng , Wang Congcong , Dai Xiaojie 
Published: June 2024

Abstract
The common squid, Todarodes pacificus, is an important commercial species that inhabits the northwest Pacific Ocean, particularly the East Japan Sea, the Pacific coast of Japan, and the East China Sea. In this study, we chose 29 individuals from three areas: one type from the Sea of Japan and two types from the East China Sea. A total of 43,529 SNPs were obtained using genotyping-by-sequencing (GBS). Our analyses revealed low genetic diversity and genetic differentiation in each type. Heterozygote deficiency and inbreeding have caused this low level of genetic diversity. Population structure analysis indicated that the three types were genetically similar, which may be attributed to strong gene flow combined with the demographic history events during the last 2 million years. This new GBS application technique provides valuable information for the conservation of marine species genetics and could be useful for the effective management of this resource.
Effect of surface roughness on interface shear strength parameters of sandy soils
Authors: Kadhim Hala K. , Alyounis Mohamad 
Published: June 2024

Abstract
Understanding the interface shear strength is crucial for the design of geotechnical structures. This study investigates the effect of surface roughness on the interface friction angle, peak interface friction coefficient, and interface shear strength through direct interface shear tests. The experiments were performed on 10 samples of concrete and steel with the level of roughness varying and soil. The objective is to provide soil parameters for a site that is located around 6 km away to the south of Al-Amarah city, Southeast of Iraq where earthquakes hit frequently. The research is intended to investigate the effect of earthquakes on objects that are built in that particular region, by putting emphasis on the interaction between the soil structure and the roughness of the contact surface between the structural parts and the soil. In order to evaluate the roughness nature of structural materials, a test program was conducted using the SRT-6210 Digital Surface Roughness Tester. The average roughness parameter (R
a) had the strongest association with shear parameters, and so it is the indicator to explain the shear behavior of sand‒concrete and sand‒steel interfaces. The direct shear box test was employed to find out the soil’s shear strength parameters as well as the interface shear strength parameters. The test shows a profound change in the shear strength characteristics of sand‒concrete and sand‒steel indispensable interfaces. As the roughness index increased. It depicted an upward slope of apparent shear strength and friction coefficient taken at the interface. The shear strength had increased by 25.13% when the roughness of the concrete was below

20
μ
m

20{\rm{\mu }}{\rm{m}}

and by 36.26% when the roughness of the steel was below

30
μ
m
.

\hspace{0.25em}30{\rm{\mu }}{\rm{m}}.\hspace{0.25em}

Moreover, sand‒steel samples interface friction angle increased by approximately 31.5% with increasing surface roughness and sand‒concrete samples by 21.54%. The results also revealed that the peak interface friction coefficient

(
μ
p
)

\left(\mu p)

increased with the increase in R
a.
Photuris mcavoyi (Coleoptera: Lampyridae): a new firefly from Delaware interdunal wetlands
Authors: Heckscher Christopher M. , Branham Marc A. 
Published: June 2024

Abstract

Photuris mcavoyi
sp. nov. (Coleoptera: Lampyridae) is described from coastal freshwater interdunal swale wetlands in Sussex County, Delaware, USA. The species is most easily diagnosed from potential sympatric congeners by the combination of a male flash pattern consisting of ∼0.5 s bright yellow signal at irregular intervals (∼3.4–4.1 s), body length (

x
‾

$\bar{x}$

= 9.8 mm) and width (

x
‾

$\bar{x}$

= 3.8 mm), pale scutellum of normal proportions (i.e., not reduced), light brown metacoxae, and pronotum vitta lacking flukes. To date, despite recent survey work at former sites occupied by the species, P. mcavoyi has not been confirmed extant since 1998. Surveys for P. mcavoyi should continue in Delaware and Maryland and should include interdunal wetlands in Virginia and New Jersey. The holotype has been deposited at the National Museum of Natural History (USNM), Washington D. C., United States.
“Survival” and “death” in Céline’s novels
Authors: Duan Huimin 
Published: June 2024

Abstract
Louis-Ferdinand Céline, a French writer of the twentieth century, was an important author during the two world wars in France. His works, set against the backdrop of these wars, depict the various aspects of human nature during wartime. “Survival” and “Death” are important themes discussed in Céline’s novels. Under the background of wars, “survival” becomes the instinct of characters in Céline’s works, but the threat of death is always present. Through the perspective of a doctor, Céline materializes “survival” and “death,” using metaphors such as “devouring,” “decomposition,” and “corrosion” to illustrate the viewpoint of “death on the installment plan,” vividly depicting the “imagination” and “fear” between “survival” and “death,” presenting the disasters and sufferings caused by wars, and expressing strong antiwar sentiments within a pessimistic view of life and death. By using semiotic isotope as a tool, we study the thematic generation process of “survival and death,” analyzing the “surface-level image paths” of the text through the “discourse images,” and then delving into the deeper layers of the text to discover the inherent and shared nuclear seme features of these images and their repetition of information, namely semiotic isotope.
Methylation regulation for FUNDC1 stability in childhood leukemia was up-regulated and facilitates metastasis and reduces ferroptosis of leukemia through mitochondrial damage by FBXL2
Authors: Tan Sihai , Ge Yirong , Bi Jing 
Published: June 2024

Abstract
Leukemia, the most common malignant tumor in childhood, can be categorized into acute leukemia and chronic leukemia. However, the role of FUNDC1 in childhood leukemia (CL) remains unknown. This study aims to investigate the effects of FUNDC1 on patients with CL and its underlying mechanism both in vivo and in vitro. The mRNA expression levels of FUNDC1 were found to be up-regulated in serum samples from CL patients as well as in leukemia cell lines. Furthermore, it was observed that the mRNA expression of FUNDC1 was lower in stage I–II CL patients compared to stage III–IV patients. The up-regulation of FUNDC1 was found to promote leukemia metastasis. Additionally, it was discovered that FUNDC1 up-regulation reduces ferroptosis by inhibiting mitochondrial damage. In a leukemia model, FUNDC1 up-regulation induces the expression of FBXL2. Moreover, FUNDC1 up-regulation reduces FBXL2 ubiquitination, thus maintaining FBXL2 protein expression in leukemia. By inducing FBXL2, FUNDC1 reduces ferroptosis in leukemia through the inhibition of mitochondrial damage. The stability of FUNDC1 is controlled by METTL3 methylation. Overall, this study sheds light on the role of FUNDC1 in CL and provides insights into its underlying mechanisms.
Validity and error analysis of calculating matrix exponential function and vector product
Authors: Tu Lihui , Hong Huanjie 
Published: June 2024

Abstract
In this study, an efficient calculation method of matrix exponential function and vector product is proposed to reduce the calculation error. This method is based on the flexible exponential integral scheme; using B-series theory and two-color tree theory, the numerical series expression is obtained, and the exponential integral of the matrix exponential function is solved. By constructing a specific numerical integration scheme and analyzing its convergence under the theoretical framework of analytic semigroups, the convergence analysis of numerical schemes is studied and perfected. The numerical results show that the proposed method of matrix exponential function and vector product has a small error, which shows obvious advantages in reducing the calculation error.
Algorithm for formation of optimum schematic solutions of local electrical power systems containing renewable sources of electric energy
Authors: Zabolotnyi A.P. , Fedosha D.V. , Diachenko V.V. 
Published: June 2024

Purpose. Formation of optimal circuit design solutions of the local mains with renewable power supply with take apart the minimum losses of electrical energy and reduct discounted costs.
Methodology. Math model of local mains with renewable power supply. The decomposition and reduction method for the structures of mains that are optimized. The method of potential surfaces. Methods of parametric optimization for the circuit design solutions.
Findings. It is noted that although the share of the renewable power supply continues to grow and develop rapidly, the industry still faces many challenges as: reduce electricity losses and annual costs, improve operation and maintenance efficiency, maintain mains stability, ensure safety and reliability of the power supply system with the renewable power supplies.
It is shown that an effective solution to these problems is possible only on the basis of the analysis of the prospects for the development of the local mains with renewable power supplies, the development of technical and organizational support mechanisms that will contribute to the construction of modern circuit design solutions.
Originality. It is proposed to apply the potential surface method for create the optimal structure of the local mains with renewable power supplies during its design and modernization, which allows optimizing the mains structure with take apart the minimum losses of electrical energy and reduct discounted costs.
Practical value. The algorithm of forming the structure of power supply systems is described, which realizes the simultaneous solution of the tasks of determining the count of the load nodes, distributing power receivers between them, determining the design of power supply, taking into account the discreteness of the design of the system elements.
The proposed formalized method of building optimal the circuit design solutions of the local mains with renewable power supplies during its design and modernization, which allows optimizing the mains structure with take apart the minimum losses of electrical energy and reduct discounted costs.
In addition, based on the joint use of evaluation and optimization models, the proposed method allows optimizing the loading of cable lines, which leads to a decrease in losses in them.
The results of numerical modeling based on the proposed algorithm are presented on the example of solving the problem of reconstruction of a section of the city mains after added renewable power supplies to it.
Rancang Bangun Mesin Pencuci Kentang
Authors: Defrian Angga , Ginting Agus , Zulfakri Zulfakri , Amrizal Amrizal , Tarigan Sumatera , Febriamto Adi 
Published: June 2024

Abstrak. Salah satu faktor penting dalam menjaga kualitas kentang adalah proses pasca panen yaitu pencucian. Proses pencucian kentang saat ini masih dilakukan secara manual oleh para petani, bahkan banyak tidak dicuci setelah proses pemanenan selesai. Hal ini mengakibatkan tampilan kentang kelihatan kurang menarik. Proses pencucian dengan cara ini mempunyai beberapa kelemahan dimana penggunaan air menjadi tidak terkontrol, juga membutuhkan ruang yang besar untuk perendaman yang banyak dan membutuhkan waktu yang lama. Oleh karena itu tujuan penelitian ini merancang dan membangun mesin pencuci kentang, dengan harapan pada pencucian kentang menjadi lebih efisien waktu dan lebih efektif. [A1] Metode yang digunakan pada perancangan ini adalah analisa perancangan, rancangan struktural, fungsional dan hasil pengamatan. Hasil penelitian ini telah merancang bangun mesin pencuci kentang dengan ukuran panjang 78,75 cm, lebar 35 cm dan tinggi 58 cm. Dari analisa perancangan didapatkan kapasitas adalah 155,24 kg/jam. Hasil pengamatan yaitu pada 1 kg kentang dengan perbedaan waktu pencucian yaitu 0,[A2] 5, 1, 1,5, dan 2 menit., didapatkan waktu pencucian yang optimal adalah 1 menit dan 1,5 menit pada beban 1 kg kentang. hasil dari 1 menit dan 1,5 menit masing-masing menghasilkan kentang yang bersih sebesar 76,92%, 84,61%, kotor 15,38%, 7,69%, dan kulit terkelupas 7,69%, 15,38%. Potato Washing Machine DesignAbstract Abstract One important factor in maintaining the quality of potatoes is the post-harvest process, namely washing. The current potato washing process is still done manually by farmers, many are not even washed after the harvesting process is complete. This results in the appearance of potatoes looking less attractive. The washing process in this way has several disadvantages where the use of water becomes uncontrolled, also requires a large space for a lot of soaking and takes a long time. Therefore the purpose of this study is to design and build a potato washing machine, with the hope that washing potatoes becomes more time efficient and more effective. The method used in this design is design analysis, structural, functional design and observation results. The results of this study have designed a potato washing machine with a length of78,75 cm, width of35 cm and height of58 cm. From the design analysis, the capacity is155.24 kg / hour. The results of the observation were on1 kg of potatoes with a difference in washing time of 0.5, 1, 1.5, and 2 minutes., the optimal washing time was 1 minute and 1.5 minutes on a load of1 kg of potatoes. The results of the observation were on1 kg of potatoes with a difference in washing time of 0.5, 1, 1.5, and 2 minutes., the optimal washing time was 1 minute and 1.5 minutes on a load of1 kg of potatoes. The results of 1 minute and 1,5 minutes resulted in clean potatoes of 76.92%, 84.61%, gross 15.38%, 7.69%, and flaky skin of 7.69%, 15.38%, respectively.
Pengaruh Kombinasi Vermikompos Dan Zeolit Terhadap Nitrogen, Fosfor, Dan Kalium Tanah Ultisol
Authors: Annisa Nur Rahma , Fikrinda Fikrinda , Zuraida Zuraida 
Published: June 2024

Abstrak. Ultisol merupakan lahan suboptimal yang memiliki kendala ketersediaan hara. Penelitian ini bertujuan untuk mengetahui pengaruh kombinasi vermikompos dan zeolit terhadap nitrogen, fosfor, dan kalium tanah Ultisol. Penelitian ini menggunakan Rancangan Acak Kelompok dengan tujuh perlakuan dan tiga ulangan sehingga terdapat 21 satuan percobaan. Faktor-faktor yang diuji yaitu kontrol (K0), 10 g pot-1 vermikompos (K1), 10 g pot-1 vermikompos+15 g pot-1 zeolit (K2), 20 g pot-1 vermikompos (K3), 20 g pot-1 vermikompos+15 g pot-1 zeolit (K4), 30 g pot-1 vermikompos (K5), 30 g pot-1 vermikompos+15 g pot-1 zeolit (K6). Hasil penelitian menunjukkan bahwa aplikasi vermikompos sebagai perlakuan tunggal maupun berkombinasi dengan zeolit meningkatkan kadar N total, P tersedia, dan K dapat dipertukarkan. Kombinasi vermikompos dan zeolit efektif meningkatkan hara kalium sedangkan aplikasi vermikompos dalam dosis tinggi (30 g pot-1) memberikan pengaruh lebih baik terhadap hara nitrogen dan fosfor pada Ultisol. The Effect Of Vermicompost And Zeolite On Nitrogen, Phosphorus, And Potassium Of Ultisol Soil Abstract. Ultisol soil is a suboptimal land that has constraints on nutrient availability. This study aimed to determine the effect of the combination of vermicompost and zeolite on nitrogen, phosphorus, and potassium in ultisol soil. This study used a Randomized Block Design with seven treatments and three replications, so there were about 21 experimental units. The factors were control (K0), 10 g pot-1 vermicompost (K1), 10 g pot-1 vermicompost + 15 g pot-1 zeolite (K2), 20 g pot-1 vermicompost (K3), 20 g pot-1 vermicompost + 15 g pot-1 zeolite (K4), 30 g pot-1 vermicompost (K5), 30 g pot-1 vermicompost + 15 g pot-1 zeolite (K6). Results showed that the vermicompost as a single treatment or in combination with zeolite had increased exchangeable K significantly. The increase of vermicompost had effect on increasing available P and exchangeable K, while the increase of zeolit had increased the exchangeable K but decreased available P. In conclusion, the best application for ultisol soil is the use of vermicompost at 30 g pot-1 (K5).
Pattern of changes in hepatic aminotransferases level during dengue infection in children aged 1-12 years
Authors: Swamy Satyawathi , Ukkali Sadashiva B. , Kulkarni Nagamani , Thobbi Achyut N. 
Published: June 2024

Background: Dengue fever is a pandemic viral disease carried by mosquito-borne flavivirus. Dengue infection is the most common arthropod infection in humans. The study is done with the aim to establish a relation between hepatic dysfunction and outcome in patients with dengue fever. It was found that hepatic transaminases were significantly deranged in dengue with warning signs indicating poor prognosis and need for early initiation of supportive treatment which can reduce mortality and morbidity in these children. Liver function tests can be of profound benefit in indicating the prognosis of children with dengue fever in resource-limited settings.
Methods: Cohort prospective observational study in Al-Ameen children hospital over 2 years. Patients aged 1-12 years fulfilling WHO case definition of fever and ≥2 of following: nausea/vomiting, rashes, aches and pains, tourniquet test positive, thrombocytopenia or any warning sign and serologically confirmed NS1Ag positive were studied. Once serologically positive, a blood sample was taken while establishing an intravenous line.
Results: Dengue with warning signs and dengue without warning signs were the classifications given to the patient. Both AST and ALT were found to be higher in groups having dengue with warning signs, with AST higher than ALT.
Conclusions: In dengue infection, hepatic dysfunction was common. Enzymes were significantly deranged in dengue with warning signs indicating prolonged illness and poor prognosis and need for early initiation of supportive treatment for better outcomes.