bluuebunny/crossref_metadata_2025_split huggingface dataset:
Variance in Pneumocystis jirovecii prophylaxis practice for pediatric patients undergoing hematopoietic cell transplantation
Authors: Lipsitt Amanda , Hijano Diego R. , Ferrolino Jose A. , Dallas Ronald , Sharma Akshay , Maron Gabriela 
Published: July 2024

AbstractPneumocystis jirovecii pneumonia (PJP) in hematopoietic cell transplant (HCT) recipients can be prevented by efficient prophylaxis. We surveyed HCT centers in North America to assess their PJP prophylaxis practices. Most institutions used intravenous (IV) pentamidine (29.6%) or inhaled pentamidine (14.8%); 37% institutions changed from trimethoprim/sulfamethoxazole (TMP‐SMX) to another medication after conditioning; and 44% administered no PJP prophylaxis during the pre‐engraftment period. Most institutions avoided using TMP‐SMX during the pre‐engraftment period, mainly because of concerns about myelotoxicity, despite this being the preferred PJP prophylaxis agent. There is a need to evaluate the effects of TMP‐SMX on engraftment.
A case of suspected autoimmune encephalopathy with involuntary movements and cognitive dysfunction post‐COVID‐19
Authors: Tenpaku Yosuke , Mabuchi Naoki , Kawase Takahiro , Oguro Hideki , Tatsumi Hiroshi , Satoh Masayuki 
Published: July 2024

AbstractBackgroundWe report a case of suspected autoimmune encephalopathy with involuntary movements and concomitant cognitive dysfunction after COVID‐19.Case PresentationThe patient is a male in his 20s who presented with fever and generalized involuntary movements and was diagnosed with COVID‐19. The involuntary movements improved slightly, and the fever resolved within a week of the diagnosis. However, about a month later, the patient presented with severe recurrence of the involuntary movements. Antiepileptic drugs were ineffective, and the patient was re‐hospitalized with suspected autoimmune encephalopathy. The electroencephalogram (EEG) was difficult to assess accurately due to involuntary movements. Neuropsychological testing on re‐admission revealed mild memory impairment, executive dysfunction, and decreased processing speed. We treated the patient with methylprednisolone (mPSL) 1000 mg/day for a total of 8 days and intravenous immunoglobulin therapy (IVIG) 27.5 g/day for 5 days. Involuntary movements were mild after 59 days. A repeat neuropsychological assessment conducted 3 weeks later showed improvement of both memory and executive functions. The patient was discharged on Day 75, and he returned to work the following month.ConclusionIn our patient reported herein, early and appropriate treatment was successful. Impaired activities of daily living and cognitive dysfunction rapidly improved. The case serves to underscore the importance of early detection and intervention for the sequelae of COVID‐19.
Optimization of physical and mechanical properties of PC/ABS/PMMA blends by mixture design approach
Authors: Ezzeddine Rahma , Elfehri Karama , Marcos‐Fernández Ángel , Samet Basma 
Published: July 2024

AbstractThis study aims to investigate the recycling of end‐of‐life computer plastics, focusing on polycarbonate (PC) and acrylonitrile–butadiene–styrene (ABS) copolymer, which constitute a significant portion of collected computers. Through differential scanning calorimetry and infrared spectroscopy analyses, the properties of raw PC, ABS and poly(methyl methacrylate) (PMMA) were evaluated. Various blends of PC and ABS were prepared, incorporating different percentages of recycled PMMA as a cost‐effective coupling agent. These blends were processed through melt compounding using a contra‐rotating twin‐screw extruder and subsequently shaped by injection molding. An experimental mixture design was applied to evaluate the mechanical and physical properties of the composite materials, including melt flow index, hardness, flexural strain at break and Charpy impact strength. The results of the desirability analysis indicated that the optimal blend for achieving a balance between mechanical and physical properties consists of a high PC content (approximately 80% or more), a low ABS content (less than 20%) and less than 5% recycled PMMA. © 2024 Society of Chemical Industry.
Differential effects of ganglioside lipids on the conformation and aggregation of islet amyloid polypeptide
Authors: McCalpin Samuel D. , Mechakra Lina , Ivanova Magdalena I. , Ramamoorthy Ayyalusamy 
Published: July 2024

AbstractDespite causing over 1 million deaths annually, Type 2 Diabetes (T2D) currently has no curative treatments. Aggregation of the islet amyloid polypeptide (hIAPP) into amyloid plaques plays an important role in the pathophysiology of T2D and thus presents a target for therapeutic intervention. The mechanism by which hIAPP aggregates contribute to the development of T2D is unclear, but it is proposed to involve disruption of cellular membranes. However, nearly all research on hIAPP‐lipid interactions has focused on anionic phospholipids, which are primarily present in the cytosolic face of plasma membranes. We seek here to characterize the effects of three gangliosides, the dominant anionic lipids in the outer leaflet of the plasma membrane, on the aggregation, structure, and toxicity of hIAPP. Our results show a dual behavior that depends on the molar ratio between the gangliosides and hIAPP. For each ganglioside, a low‐lipid:peptide ratio enhances hIAPP aggregation and alters the morphology of hIAPP fibrils, while a high ratio eliminates aggregation and stabilizes an α‐helix‐rich hIAPP conformation. A more negative lipid charge more efficiently promotes aggregation, and a larger lipid headgroup improves inhibition of aggregation. hIAPP also alters the phase transitions of the lipids, favoring spherical micelles over larger tubular micelles. We discuss our results in the context of the available lipid surface area for hIAPP binding and speculate on a role for gangliosides in facilitating toxic hIAPP aggregation.
Allergic bronchopulmonary mycosis in Schizophyllum commune with positive Aspergillus‐specific IgE antibodies: A case report
Authors: Takahashi Hiroshi , Hamakawa Masamitsu , Ishida Tadashi , Watanabe Akira 
Published: July 2024

AbstractSchizophyllum commune is the third most common causative fungus of allergic bronchopulmonary mycosis(ABPM). Two‐thirds of ABPM caused by S. commune can be positive for Aspergillus fumigatus‐specific IgE, which can be difficult to diagnose. Our patient presented to our hospital with wet cough for 3 months and chest pain for 3 days. Blood tests showed IgE 1522 IU/mL, eosinophils 688/mm3, A. fumigatus ‐specific IgE 2.24 UA/mL, and chest computed tomography showed high‐attenuation mucus. Bronchoscopy showed mucus plugs and speculum examination showed filamentous fungi, but various culture tests did not detect A. fumigatus, Asp f 1‐specific IgE was negative, and S. commune was detected in the culture of bronchial washing. Since he was positive for S. commune‐specific IgE and IgG, he diagnosed ABPM caused by S. commune. These findings demonstrate the importance of identifying the causative fungus in ABPM by detailed examination.
Trimethoprim‐sulfamethoxazole acute respiratory distress syndrome requiring lung transplantation
Authors: Donnan Matthew , Siemienowicz Miranda , Tay Hui Sien , McLean Catriona , Philpot Steve , Mason Chris , Snell Greg , Glaspole Ian , Stirling Rob G. 
Published: July 2024

AbstractTrimethoprim‐sulfamethoxazole (TMP‐SMX) acute respiratory distress syndrome (ARDS) is a rare, but severe complication of a commonly prescribed antibiotic. TMP‐SMX typically affects young, otherwise well patients with a specific human leukocyte antigen type (HLA‐B*07:02 and HLA‐C*07:02). The condition is poorly understood with a unique pathological appearance and mechanism that remains unclear. Mortality rate is greater than one third. We describe the case of a previously well 18‐year‐old woman treated with a prolonged course of TMP‐SMX for a complex urinary tract infection who developed rapidly progressive respiratory failure requiring prolonged intensive care admission, extra‐corporeal membranous oxygenation, and eventual lung transplantation. No targeted treatment exists, further research is required to better understand disease pathogenetic mechanisms and potential therapeutic interventions.
The effect of trapping on the migration and survival of Atlantic salmon smolts
Authors: Sortland Lene Klubben , Jepsen Niels , Kennedy Richard , Koed Anders , del Villar‐Guerra Diego , Lennox Robert J. , Birnie‐Gauvin Kim , Aarestrup Kim 
Published: July 2024

AbstractElectronic tags are often used to track the freshwater‐marine migrations of smolts, where smolts are captured for tagging pre‐migration (e.g., via electrofishing) or during‐migration (e.g., via traps). Pre‐migration capture allows smolts to initiate and complete their downstream migration unhindered, but risks smolt loss before the migration commences. The contrary is the case for during‐migration trap‐caught smolts, but trapping smolts temporarily halts their seaward journey which may negatively impact their progress. This study investigated the effect of trapping on the behaviour and survival of migrating Atlantic salmon (Salmo Salar) smolts using acoustic telemetry. We compared the movements and survival of smolts tagged before the smolt run captured by electrofishing (“comparator”) with smolts trapped and tagged during the smolt run (“trapped”). A total of 478 smolts were tagged and released in River Skjern (2020 and 2022), Denmark, and 82 smolts in River Ballycastle (2022), Northern Ireland, and their seaward movements were monitored using acoustic receivers deployed in the river, fjord, and coastal area. In River Skjern in 2022, comparator smolts migrated earlier than trapped smolts, likely because these constituted more of the larger‐sized, earlier migrating individuals. We found no differences in descent trajectories, diel patterns, progression rates, or survival between trapped smolts and comparator smolts in any of the rivers or study years. Thus, our results support the use of during‐migration trapping as a low‐impact method to capture smolts for telemetry studies, with trapped samples (if held <24 h) yielding comparable results in terms of behaviour and survival with non‐delayed pre‐migration tagged fish.
Clay soil amendment suppressed microbial enzymatic activities while increasing nitrogen availability in sandy soils
Authors: Poudel Pratima , Ye Rongzhong , Parajuli Binaya 
Published: July 2024

AbstractConservation management practices often produced positive but limited desirable outcomes in US Southeast sandy soils, likely due to their intrinsically low clay contents that constrain the soil's capacity to preserve organic carbon (C) and nutrients. In the field, we tested the effectiveness of a novel approach, that is, clay soil amendment, to improve sandy soils. In October 2017, clay‐rich soils (25% clay) were spread at 25 metric tons ha−1 and tilled onto a sandy soil (1.9% clay) in the field, which was further mixed by light tillage at 0‐ to 15‐cm depth, followed by planting winter cover crop mixtures (cereal rye, crimson clover, and winter pea). The crop rotation was cotton and corn with cover crop mixtures planted in the winter fallow season. Soils (0–15 cm) were collected in August 2021 and subjected to physio‐biochemical analyses. Clay amendment increased soil clay content to 3.4%, which improved nitrogen (N) availability by 51% but inhibited the activities of C (β‐d‐cellubiosidase [CB]; β‐xylosidase [BX]; N‐acetyl‐β‐glucosaminidase [NAG]) and N (leucine aminopeptidase [LAP]) cycling enzymes, resulting in up to 78% reduction in microbial respiration. A follow‐up kinetic study on BG and LAP enzymes suggested that clay addition can have different impacts on enzymes with diverse biological origins through distinct mechanisms. Clay addition can potentially improve sandy soils by stabilizing the organic inputs in soils. However, more research is required to understand its long‐term impacts making this approach practical.
Recent Advances of Bio‐Based Hydrogel Derived Interfacial Evaporator for Sustainable Water and Collaborative Energy Storage Applications
Authors: Chen Jiachuan , Wang Xiaofa , Wang Baobin , Wu Ting , Zhang Lei , Zhang Kai , Fang Guigan , Wang Yueying , Zhao Yu , Yang Guihua 
Published: July 2024

AbstractSolar interfacial evaporation strategy (SIES) has shown great potential to deal with water scarcity and energy crisis. Biobased hydrogel derived interfacial evaporator can realize efficient evaporation due to the unique structure‐ properties relationship. As such, increasing studies have focused on water treatment or even potential accompanying advanced energy storage applications with respect of efficiency and mechanism of bio‐based hydrogel derived interfacial evaporation from microscale to molecular scale. In this review, the interrelationship between efficient interfacial evaporator and bio‐based hydrogel is first presented. Then, special attention is paid on the inherent molecular characteristics of the biopolymer related to the up‐to‐date studies of promising biopolymers derived interfacial evaporator with the objective to showcase the unique superiority of biopolymer. In addition, the applications of the bio‐based hydrogels are highlighted concerning the aspects including water desalination, water decontamination atmospheric water harvesting, energy storage and conversion. Finally, the challenges and future perspectives are given to unveil the bottleneck of the biobased hydrogel derived SIES in sustainable water and other energy storage applications.
C─H Activation Enables the Construction of New Bis‐Polyaryl Phenylpyridine Ruthenium Complexes: Conjugation and Rigidity Synergistic Effect for Advanced Electrochemiluminescence
Authors: Malik Fazal , Sun Yuzhu , Lv Huiping , Yan Yuting , Masota Magoti , Chen Mingyue , Ji Hongfei , Zhang Libing , Dang Yanfeng , Zhang Ruizhong , Huang Jianhui 
Published: July 2024

AbstractThe access to bench‐stable organometallic compounds unfolds new chemical space for medicinal and material sciences. In particular, stable organoruthenium compounds with constitutional and stereoisomeric forms for subtle regulation of electrochemiluminescence are intriguing and challenging. Here, coordination of polycyclic aromatic hydrocarbons on (2‐phenylpyridine)2(CO)2Ru complex allows access to bis‐polyaryl phenylpyridine (BPP) Ruthenium complex through C─H activation strategy and coupling reactions for installation of the functionalities with steric and electronic purposes. The photoluminescence and electrochemiluminescence of BPP Ru complexes are affected by the actual polycyclic aromatic hydrocarbons inherent properties. The anthracene derivatized BPP Ru complex (BPP‐Ant) shows the best ECL performance and reveals an enormous ECL quantum efficiency of 1.6‐fold higher than the golden standard Ru(bpy)32+. The unprecedentedly high efficiency is due to the best compromise between the structural conjugation and molecular rigidity from BPP‐Ant providing a providential energy gap that facilitated the feasibility of electron transfer and favored the radiative energy release by experimentally and DFT calculations. Moreover, PL and spooling ECL spectroscopies are used to track and link multiple emission peaks of BPP‐Ant at 445, 645, and 845 nm to different emissive species. These discoveries will add a new member to the efficient ECL ruthenium complex family and bring more potentials.
Microporous Cobalt Ferrite with Bio‐Carbon Loosely Decorated to Construct Multi‐Functional Composite for Dye Adsorption, Anti‐Bacteria and Electromagnetic Protection
Authors: Ma Guojuan , Lan Di , Zhang Yi , Sun Xiyuan , Jia Zirui , Wu Guanglei , Bu Guixian , Yin Pengfei 
Published: July 2024

AbstractCurrently, facing electromagnetic protection requirement under complex aqueous environments, the bacterial reproduction and organic dye corrosion may affect the composition and micro‐structures of absorbers to weaken their electromagnetic properties. To address such problems, herein, a series of CoFe2O4@BCNPs (cobalt ferrite @ bio‐carbon nanoparticles) composites are synthesized via co‐hydrothermal and calcining process. The coupling of magnetic cobalt ferrite and dielectric bio‐carbon derived from Apium can endow the composite multiple absorption mechanisms and matched impedance for effective microwave absorption, attaining a bandwidth of 8.12 GHz at 2.36 mm and an intensity of −49.85 dB at 3.0 mm. Due to the ROS (reactive oxygen species) stimulation ability and heavy metal ions of cobalt ferrite, the composite realizes an excellent antibacterial efficiency of 99% against Gram negative bacteria of Escherichia coli. Moreover, the loose porous layer of surface stacked bio‐carbon can promote the adsorption of methylene blue for subsequent eliminating, a high removal rate of 90.37% for organic dye can be also achieved. This paper offers a new insight for rational design of composite's component and micro‐structure to construct multi‐functional microwave absorber for satisfying the electromagnetic protection demand in complicated environments.
Aligning technical knowledge to an industry domain in global software development: A systematic mapping
Authors: de Campos Vitor , David José Maria N. , Ströele Victor , Braga Regina 
Published: July 2024

AbstractFinding software developers with expertise in specific technologies that align with industry domains is an increasingly critical requirement. However, due to the ever‐changing nature of the technology industry, locating these professionals has become a significant challenge for companies and institutions. This research presents a comprehensive overview of studies exploring suitable recommendation systems that can assist companies in addressing this pressing need. To conduct this study, we employ a hybrid systematic mapping approach with an initial number of 1,251 studies and a final selection of 21 studies. Our work focuses on collecting data on key technologies, methodologies, and data sets utilized in proposed recommendation systems, to design a new recommendation system that can effectively identify specialists capable of aligning specific technical knowledge with industry domains. The outcomes of this study include insights into the current research trends in this field, alongside a practical overview of considerations necessary for developing a recommendation system that successfully meets the criteria for aligning technical skills with industry domains. By following a hybrid systematic mapping methodology and presenting the outcomes in the form of insights, this research addresses the challenge of finding software developers with domain‐specific expertise in a rapidly changing technology industry, laying the groundwork for aligning technical skills with industry domains.
AuBr3 Induces CsPb(Br/I)3 QDs to Self‐Assemble into Nanowires
Authors: Mu Shouying , He Ye , Wang YueLi , Chen Wei , Lv Chunyan , Liang Xiaojuan , Xiang Weidong , Chen Zhaopin 
Published: July 2024

AbstractPerovskite quantum dots can form various forms such as nanowires, nanorods, and nanosheets through self‐assembly. Nanoscale self‐assembly can be used to fabricate materials with excellent device properties. This study introduces AuBr3 into CsPb(Br/I)3 quantum dots, causing them to assemble into nanowires. The nanowires form because part of Au3+ is surface‐doped to replace Pb2+, and the [PbX6]4− octahedral structure is distorted. The symmetry of the structural surface is broken, and a dipole‐moment‐induced field is generated, thus promoting self‐assembly. Moreover, the presence of Au nanoparticles (NPs) causes a localized surface plasmon resonance and generates strong van der Waals forces that promote self‐assembly. Finally, to test other applications of perovskite nanowires, the solution method is used to prepare films by compounding the sample solution and polystyrene (PS) for backlighted displays.
Platelet transfusion prior to major surgery in a thrombocytopenic dog
Authors: Thompson Layla , Raszplewicz Joanna , Smith Matthew 
Published: July 2024

AbstractFresh platelet concentrate (FPC) is described as the product of choice for the control of bleeding due to severe thrombocytopenia and has recently become commercially available in the UK. We report a successful, prophylactic FPC transfusion when given in combination with tranexamic acid prior to fracture repair in a 4‐year‐old Whippet. The patient presented with right radial and ulnar fractures and severe thrombocytopenia (platelet count 23 × 109/L). Viscoelastic coagulation monitoring (VCM) revealed coagulopathy, with prolonged clot formation times, but other coagulation parameters were within normal limits. One unit (65 mL) of FPC was given pre‐operatively. The dog underwent surgery without excessive bleeding and experienced no complications. Post‐transfusion VCM showed improved clot formation and clot strength. Transfusion of FPC in combination with tranexamic acid increased this dog's ability to clot, suggesting that it is an effective perioperative therapy for severely thrombocytopenic patients requiring urgent surgery.
Storm Ciarán's effect on the boiling point of water in the southeast of the United Kingdom
Authors: Harrison Giles , Bennett Alec , Miller Caleb , Bullock David 
Published: July 2024

AbstractThe spatial atmospheric pressure field due to Storm Ciarán is investigated in the south‐east of the UK at high temporal and spatial resolution using data from roadside sites. During Ciarán’s passage, a reduction in the boiling point of water was measured at Reading, from which a wider effect on the boiling point of water associated with Ciarán was calculated for the populated regions of the southeast and London. For many people in this region on 2 November 2023, the boiling point of water at breakfast time would have been below the recommended temperature range for optimal brewing of tea.
Insights into metachronal propulsion's influence on Ellis fluid flow across tri‐layers amid dynamic thermal transport: Theoretical study
Authors: Shaheen Sidra , Arain Muhmmad Bilal , Ijaz Nouman , Duraihem Faisal Z. , Hu Junhui 
Published: July 2024

AbstractCilia‐based therapies are emerging for treating ciliopathies, such as inhalable drugs to propel mucus out of the lungs of patients with cystic fibrosis. This has motivated scientists and researchers to investigate cilia motion mechanics and viscoelastic fluid properties for biomedical engineering applications and disease treatments. In line with the diverse biological implications, this study focuses on the mass and heat transfer flow of tri‐layered non‐Newtonian fluids propelled by ciliary beating in a cylindrical tube. The fluid remains incompressible, with distinct layers that do not mix. The study considers the impact of mass and heat transfer in three distinct regimes, ensuring continuity at the interfaces. Mathematical modeling incorporating the lubrication approximation, small Reynolds number, and long wavelength approximation is employed for simplification. The resulting differential equations, along with boundary conditions, yield accurate solutions for temperature, velocity, and concentration fields in the three fluid layers and are discussed graphically. Key findings demonstrate that velocity and temperature fields are most pronounced in the inner fluid layer (PCL), while the concentration profile is most prominent in the outer layers (ACL), with moderate behavior in the central region. The implications of this research extend to diverse fields, including mucus clearance from the respiratory tract, microfluidics, esophageal transport, biofluid mechanics, and other areas of physiology. The insights gained from this study have promising applications in developing new treatments and biomedical engineering solutions.