bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Synthesis of N4‐(6‐Aminopyridin‐2‐yl)‐2′‐deoxycytidine for Recognizing the CG Base Pair at Neutral pH by Oligodeoxyribonucleotide‐Directed Triple Helix Formation
Authors: Chin T.‐M. , Chung K.‐Y. , Chen J.‐J. , Lin W.‐C. , Kan L.‐S. 
Published: May 2015

AbstractThe sequence‐specific recognition of double‐helical DNA by oligodeoxyribonucleotide‐directed triple helix (triplex) formation is limited mostly to purine tracts. To interrupt the purine tract in a target sequence, a non‐natural deoxyribonucleoside N4‐(6‐aminopyridin‐2‐yl)‐2′‐deoxycytidine (pC) was designed to interact with the C base in the CG base pair. The protected phosphoramidite synthon of pC was synthesized in seven steps and then was incorporated into an oligodeoxyribonucleotide by an automatic DNA synthesizer. Two 22‐mers, designated as C2 and P, with a common sequence of 5′‐d‐TmCTXTmCTTCTGTCTCCAGACAG were synthesized in this study. mC is 5‐methyl‐2′‐deoxycytidine and X is either 2′‐deoxycytidine (C) or pC for C2 and P, respectively. C2 is able to form a paper clip type triplex with one C · CG mismatched base triad in slightly acidic conditions but not at the neutral pH. On the other hand, P forms a stable triplex under both acidic and neutral conditions. This indicates that pC is able to form a pC · CG base triad in the triplex. Their physical properties were studied by UV thermal melting experiments and circular dichorism spectroscopy (CD). The thermal melting results imply that the pC · CG base triad is as stable as the C+ · GC triad at pH 6.0, and pC helps the triplex formation preferably at neutral to acidic pH. In addition to the hydrogen bonding interaction with the CG base pair, the hydrophobic interaction of pC may also play an important role in stabilizing the triplex formation of oligodeoxyribonucleotides. In the presence of spermine at either pH 5.0 or pH 6.0, the melting temperature of the third strand of P was elevated about 30 and 21 °C, respectively. Thus, spermine can enhance the stability of the triple‐helical structure.
25Mg NMR Relaxation Study of Mg2+‐ATP Complexation in Solutions
Authors: Shien Zhi‐Shian , Luo Tzy‐Jiun , Hwang Lian‐Pin 
Published: May 2015

Abstract25Mg NMR relaxation has been applied to characterize the kinetic and dynamic parameters in the complexation process of the Mg2+ ion with adenosine triphosphate. A modified linear prediction with singular value decomposition method developed earlier is used to obtain the preliminary chemical shift separation between the free 25Mg2+ ion and the 25Mg2+‐ATP complex. Then the 25Mg2+ NMR null point spectra is invoked to find the chemical shift separation and the quadrupolar coupling constant of the complex. With the knowledge of those parameters, T1 and line width data at 30.62 MHz and 18.37 MHz can be analyzed to determine the correlation times for the fluctuation of electric field gradient at 25Mg and the dissociation rate constants of the complex at the temperature range of 270–320 K. An activation energy of 8.8 kcal/mol for dissociation rate constant is obtained. It is also found that the reorientational motion of the 25Mg2+‐ATP complex is not significantly affected by the formation of ATP aggregates. A similar conclusion is further obtained by comparing the T1 data of β‐31P in ATP and Mg2+‐ATP solutions.
Sequence Analyses in PDPS/PDMS Statistical Random Copolymers
Authors: Yang Mei‐Hui , Hwang Yeun‐Hsing , Liu Jiann‐Chang 
Published: May 2015

AbstractThe anionic copolymerization of hexaphenylcyclotrisiloxane (P3) and hexamethylcyclotrisiloxane (D3) under non‐equilibrium conditions was carried out for synthesizing a series of poly(diphenylsiloxane‐stat‐dimethylsiloxane) copolymers. The sequence analyses of these copolymers were studied. Sequence distribution up to the pentad level is observable in the 1H NMR spectrum. The sequence distributions calculated from a pentad model by using Bovey's method, interpret the 1H NMR spectra (SiCH3 only) of all the copolymers very well. However, the triad model was only valid for relatively lower P3 content (< 50 mol%) copolymers.
Preparation of Chiral Phosphorus(V) Reagents and Their Uses with Borane in the Enantioselective Reduction of Ketones
Authors: Chen Guo‐Hsian , Hsu Jue‐Liang , Yang Wen‐Bin , Fang Jim‐Min , Lee Gene‐Hsiang , Liu Yi‐Hung , Wang Yu 
Published: May 2015

AbstractChiral pentavalent phosphorus reagents 5–17 were prepared from POCl3 and ephedrine (or the related α‐amino alcohols), followed by substitution with nucleophiles of phenylmagnesium bromide, alcohols, amines, diamines and triamines. The substitution reactions occurred in a stereospecific manner with retention of the configuration at the phosphorus center. The structures of these phosphorus(V) reagents were determined by spectral methods and verified by X‐ray diffraction in several instances. These phosphorus(V) reagents were used with borane/dimethylsulfide complex in the enantioselective reduction of aromatic, aliphatic and heterocyclic ketones. The phosphorus(V) reagents likely functioned as Lewis bases to react with borane, forming in situ zwitterionic species as the chiral reducing agents. The reactions were generally carried out at 0 °C in tetrahydrofuran solution with a molar ratio of ketone/borane/phosphoramidate = 1:1:0.2 to afford secondary alcohols with modest enantioselectivity, up to 67% ee in the reduction of 4′‐methylacetophenone.
Chemical Constituents of the Pericarp of Platycladus orientalis
Authors: Kuo Yueh‐Hsiung , Chen Wen‐Chin 
Published: May 2015

AbstractIn previous papers, we have reported two new compounds, 15‐hydroxypinusolidic acid and platydiol, from the pericarp of Platycladus orientalis. In addition to the above compounds, the isolation and identification of twenty‐one compounds from the same source are described. Their structures were determined on the basis of spectral evidence as well as direct comparison with authentic samples. These compounds included four fatty alcohols and acids, three monolignols, one sesquiterpene, nine diterpenes, two steroids, one flavone, and one sugar. Among these, docosyl 3‐hydroxyferulate is a new compound. And docosyl trans‐ and cis‐ferulates were isolated in pure form.
Organocopper Mediated Conjugate Addition of Vinyl Grignard Reagent to α,β‐Unsaturated Acylsilane
Authors: Tsai Yeun‐Min , Sieh Jiuen‐Ahn 
Published: May 2015

AbstractVinyl Grignard reagent added to trans‐cinnamaldehyde in the presence of cuprous iodide to give conjugate addition product in good yield.
A NMR Chemical Shift Analysis on Two Nonconjugated Tri‐π‐Systems
Authors: Chow Tahsin J. , Chu Kuo‐Pin , Liu Shou‐Shun , Liu Ching‐Yang 
Published: May 2015

AbstractElectronic interactions in two nonconjugated tri‐π systems are analyzed in terms of 13C NMR chemical shifts. Comparisons of chemical shift values (Δδ) among di‐methylenes, di‐ketones and methylene‐ketones support the presence of electron delocalization among the three π moieties.
A Sensitive Measurement of Maleic Hydrazide by a Differential Pulse Voltammetry Followed by a Cleansing Pulse Train
Authors: Lin Meng Shan , Jan Bor Iuan 
Published: May 2015

AbstractIn this current project, we report the most sensitive scheme for the measurement of maleic hydrazide by a modified differential pulse voltammetry (DPV) which is composed of a conventional DPV followed with a cleansing pulse train. The absorbed oxidized species (1,2‐pyridazine‐3,6‐dione) on the solid electrode surface cause subsequent mass transfer hindrance which can be removed easily by a cleansing pulse train of ±0.1 volts, 50 Hz for 5 minutes at the end of each voltammetric run. This scheme possesses the advantage of high sensitivity (submicro‐molar range), which may be used in sensitive maleic hydrazide measurement or toxicity studies.This scheme offers a better tool to study a very low concentration of maleic hydrazide. A slope of 59.2 mV per decades from the potential versus pH plot was obtained. This result indicates that these are two electrons and two protons oxidation processes. The linear range of the calibration plot is up to 50 μM with a correlation coefficient of 0.9999. The sensitivity of the linear portion of the calibration plot yields a slope of 13.63 nA/μM with a detection limit of 20 nM (S/N = 3). The width of half peak width is 100 mV at the injection of 22 μM maleic hydrazide. Precision study possesses a relative standard deviation of 4.1% (n = 20).
Application of Cryptand/Polystyrene Drift‐Type Phase Transfer Catalysts for Reduction of Ketones
Authors: Li Jane‐Hwa , Shih Jeng‐Shong 
Published: May 2015

AbstractA drift‐type phase transfer catalyst, cryptand‐22, adsorbed on poly(styrene/diviny benzene)‐sulfonic resin was prepared and applied to catalyze the reduction of ketones, e.g., acetophenone, benzophenone and benzaldehyde with NaBH4 as a reducing agent. Before the reaction, cryptand‐22 was adsorbed on the sulfonic resin with ion‐pairing, resin‐SO3− +NH‐cryptand‐22. The ion‐pairs can be destroyed by adjusting the basicity of the reaction solution with NaOH and the cryptand can be released from the resin into the reaction solution as a homogeneous catalyst during the reaction period. After the reaction, the cryptand catalyst can be readsorbed on the resin by adjusting the acidity of the solution with HCl and can be readily recovered by filtration like a heterogeneous catalyst. The draft‐type cryptand catalyst exhibited better catalytic ability than some common crown ethers, e.g., 15‐crown‐5, benzo‐15‐crown‐5, 12‐crown‐4 and dibenzo‐18‐crown‐6 for the reduction of acetophenone with NaBH4. Effects of solvents, pH of solutions, concentration of the catalyst, reducing agents and resin property on the reduction of ketones were investigated and discussed. The reaction mechanism of the cryptand catalyzed reduction was also studied.
The First Total Synthesis of Preverecynarmin
Authors: Lan Jiong , Liu Zuosheng , Li Yulin , Cen Wen , Xing Yacheng 
Published: May 2015

AbstractPreverecynarmin, isolated from a pennatulacean coral, has been synthesized from E,E‐farnesol. The key steps are alkylation of the cyanohydrin trimethylsilyl ether 5 with the halide 6, the regioselective epoxidation of the siloxyl ether 9, and the intramolecular macrocyclization of the siloxyl ether 12 induced by Ti(0).
Synthesis of New 2‐[(Substituted‐pyrazol‐1‐yl)carbonyl]‐thieno[2,3b]pyridine Derivatives Using 1,3‐Diketones, Alkylethoxymethylenes and Ketene Dithioacetals
Authors: Ho Yuh‐Wen 
Published: May 2015

AbstractThe reaction of 3‐amino‐4,6‐dimethyl‐2‐thieno[2,3‐b]pyridine carbohydrazide (1) with appropriate 1,3‐diketones 2a‐2d in glacial acetic acid afforded 3‐amino‐2‐[(3,5‐disubstituted‐pyrazo)‐1‐yl)carbonyl]‐4,6‐dimethylthieno[2,3‐b]pyridines 3a‐3d. 3‐Amino‐2‐[(5‐amino‐3,4‐disubstituted‐pyrazol‐1‐yl)carbonyl]‐4,6‐dimethylthieno[2,3‐b]pyridines 5a‐5h were also prepared by treatment of carbohydrazide 1 with appropriate alkylethoxymethylenes and ketene dithioacetals 4a‐4h, respectively.
Oxidative Cleavage of o‐Hydroxyphenyl Phosphate by Iodobenzene Diacetate
Authors: Wu Pei‐Lin , Chen Jhy‐Hong , Huang Ded‐Shih 
Published: May 2015

AbstractThe protecting o‐hydroxyphenyl group in the synthesis of mono‐ or dialkyl phosphates (6 or 8) could be removed by oxidative cleavage of mono‐ or dialkyl o‐hydroxyphenyl phosphates (3 or 7) using iodobenzene diacetate.
Photoredox Properties of Iron(III) Fluoro Complexes Containing Tetradentate Open‐Chain N2O2Ligands
Authors: Šima Jozef , Mrázová Juliana , Kotočová Adela 
Published: May 2015

AbstractTetradentate open‐chain Schiff base N2O2‐ligands of acacen, benacen or salen type and fluoride anions F− coordinate to the iron(III) central atom in methanol forming the complexes [Fe(N2O2)(CH3OH)F]. The complexes do not undergo spontaneous redox changes when kept in the dark. Their irradiation into intraligand or ligand‐to‐metal charge transfer bands causes the photoreduction of Fe(III) to Fe(II) associated with oxidation of metanol to its radical CH2OH. The final products of the primary photoredox and secondary dark redox processes, Fe(II) and CH2O, are formed in a 2:1 molar ratio. The efficiency of the axial methanol ligand photooxidation is strongly wavelength dependent and influenced by the peripheral groups R of the tetradentate ligands
Structural Characterization of Metal Ions Incorporated in Molecular Sieve Frameworks
Authors: Wei An‐Chyi , Chao Kuei‐Jung 
Published: May 2015

AbstractIsomorphous and non‐isomorphous substitutions of transition metal and IIIA elements for framework atoms of molecular sieves are very interesting in order to modify their acidic and redox catalytic properties. In this paper, we review the interaction between metal cations other than Al+3 with zeolitic frameworks in Ti, Co, V and Ga‐containing silicate and aluminophosphate zeolites detected by spectroscopic investigations. During synthesis and redox treatments, solvent, oxidant and surface silanol groups sometimes were found to attach to the framework metal ion sites, perhaps involved in the variation from tetrahedral to non‐tetrahedral coordinations.
Applications of Intramolecular Cyclopropanations of Chiral Secondary Allylic Diazoacetates
Authors: Martin Stephen F. , Hillier Michael C. 
Published: May 2015

AbstractThe diastereomeric secondary allylic diazoacetates 6a,b and 8a,b, which were readily prepared from the common intermediate 4, were cyclized in the presence of the achiral catalyst Cu(TBS)2 to furnish mixtures of the adducts 9a,b/10a,b and 12a,b/13a,b, respectively; in these cyclizations, the diastereoselectivity of the reaction was substrate controlled. When 6a,b and 8a,b were cyclized in the presence of the chiral catalysts Rh2[(5S)‐MEPY]4 or Rh2[(5R)‐MEPY]4, the substrate‐based selectivity could be reversed if the chirality of the substrate and catalyst were matched. The advantages associated with the use of chiral catalysts to effect the diastereoselective cyclization of chiral allylic diazoacetates were demonstrated by the synthesis of 25, which comprises the cyclopropane subunit found in the diterpene ingol B (14).
Homologous SNV Reaction: Synthesis of l‐Methyl‐4‐[4′‐phenylsulfonyl‐1′,3′‐butadienyl]pyridinium Iodide and Its Reactivity with Thiol Groups Giving Rise to the Chromophoric Thioether
Authors: Holler Michel , Burger Alain , Biellmann Jean‐François 
Published: May 2015

AbstractThioether 4‐[(1′E,3′E)‐4′‐phenylsulfanyl‐1,3′‐butadienyl]pyridine 8 and sulfone 4‐(4′‐phenylsulfonyl‐1′,3′‐butadienyl)pyridine 14 were prepared by reaction of the carbanions derived from allylic thioether or allylic sulfone with isonicotinaldehyde. The reaction with the sulfonyl carbanion occurred at the α position and on heating the alcolate gave the dienic sulfone 14. The corresponding pyridinium iodide 10 and 15 were prepared by reaction with methyl iodide, respectively, on pyridine derivates 8 and 14. The dienic pyridinium thioether 10 showed a long wavelength absorption band centered at 420 nm. The reaction of dienic pyridinium sulfone 15 with thiophenol gave the dienic pyridinium thioether 10 by a nucleophilic vinylic substitution. The reaction of sulfone 15 with glutathione was of second order and the rate constant was 8.5 M−1s−1 at 30°C and pH 7, about 500 times smaller than the rate constant observed with (E)‐1‐methyl‐4‐(2‐methylsulfonyl‐1‐ethenyl)pyridinium iodide 1. The dienic pyridinium thioether 10 was a negative solvatochrome.
Enantioselective Syntheses of Substituted γ‐Butyrolactones
Authors: Eliel Ernest L. , Bai Xu , Ohwa Masaki 
Published: May 2015

AbstractThe previously described chiral 2‐acyloxathianes 5 (Scheme I) are used in two different enantioselective syntheses of γ‐butyrolactones. In one synthesis, Grignard addition, cleavage and reduction to carbinols RR'C(OH)CH2OH is followed by tosylation, malonate homologation, lactonization, and removal of the carbomethoxy group to give optically active γ‐lactones. A modification of this synthesis (Scheme I) leads to optically active α‐methylene‐γ‐lactones.In the second synthesis, reaction of a bromomagnesium enolate with ketones 5 leads to β‐hydroxyesters, which, by appropriate sequences of reduction and cleavage (Scheme II) are converted to optically active α‐ or β‐hydroxy‐γ‐lactones.
Solvent and Substituent Effects in the Solvolysis of 9‐Aryl‐9‐bromofluorenes
Authors: Liu Kwang‐Ting , Lin Yen‐Shyi 
Published: May 2015

AbstractThe solvolysis of eight 9‐aryl‐9‐bromofluorenes (6b∼6i) in a variety of solvents were studied. Correlation analysis using single‐parameter Grunwald‐Winstein equation (Eqn. 1) with different Y scales showed good linearity (R ≥ 0.98) for most cases if YxBnBr was employed. Linear relationships were observed from Hammett‐type analysis of logarithm of rate constants using Brown‐Okamoto σ+ constants (Eqn. 3), although inverse order of k(p‐CF3)/k(m‐ CF3) was realized in a number of cases. The ρ values were found to vary slightly with different solvent systems. Calculated atomic charge reveals the similarity between 9‐phenyl‐9‐fluorenyl cation (7) and triphenylmethyl cation (8). An extended charge delocalization throughout the fluorenyl ring led to the conclusion of the insignificance of antiaromaticity, which was in harmony with that obtained in previous studies. The variation of relative kBr/kCl rate ratios was attributed to the electrophilic pull by solvents in solvolysis.
Chelating and Tellurolate Ligand‐Transfer Studies of the Complex fac‐[Fe(CO)3(TePh)3]−: Crystal Structures of Heterodinuclear (CO)3Mn(μ‐TePh)3Fe(CO)3 and CpNi(TePh)(PPh3)
Authors: Hsieh Chien‐Kuo , Lo Feng‐Chun , Lee Gene‐Hsiang , Peng Shie‐Ming , Liaw Wen‐Feng 
Published: May 2015

AbstractComplex fac‐[Fe(CO)3(TePh)3]− was employed as a “metallo chelating” ligand to synthesize the neutral (CO)3Mn(μ‐TePh)3Fe(CO)3 obtained in a one‐step synthesis by treating fac‐[Fe(CO)3(TePh)3]− with fac‐[Mn‐(CO)3(CH3CN)3]+. It seems reasonable to conclude that the d6 Fe(II) [(CO)3Fe(TePh)3]− fragment is isolobal with the d6 Mn(I) [(CO)3Mn(TePh)3]2− fragment in complex (CO)3Mn(μ‐TePh)3Fe(CO)3. Addition of fac‐[Fe(CO)3(TePh)3]− to the CpNi(I)(PPh3) in THF resulted in formation of the neutral CpNi(TePh)(PPh3) also obtained from reaction of CpNi(I)(PPh3) and [Na][TePh] in MeOH. This investigation shows that fac‐[Fe(CO)3(TePh)3]− serves as a tridentate metallo ligand and tellurolate ligand‐transfer reagent. The study also indicated that the fac‐[Fe(CO)3(SePh)3]− may serve as a better tridentate metallo ligand and chalcogenolate ligand‐transfer reagent than fac‐[Fe(CO)3(TePh)3]− in the syntheses of heterometallic chalcogenolate complexes.
Stoichiometric vs Catalytic MeLi Reaction with the Mixture of (ẽ5‐C5H5)Fe(CO)2l and P(OR)3: Nucleophilic Methylation vs Arbuzov‐Like Dealkylation
Authors: Uche B. Eke , Liao Yi‐Hsien , Wen Yuh‐Sheng , Liu Ling‐Kang 
Published: May 2015

AbstractThe reaction of stoichiometric MeLi with the 1:1 mixture of (ẽ5‐C5H5)Fe(CO)2I/P(OR)3 (R = Me, Et, and Ph) at −78°C changes the bonding mode between metal and ring from (ẽ5‐C5H5) to (ẽ4‐exo‐MeC5H5) and the oxidation state of metal from Fe(II) to Fe(O), the novel complexes (ẽ4‐exo‐MeC5H5)Fe(CO)2P(C)R)3 being obtained in 45‐57% yields. The reaction of trace MeLi with the 1:1 mixture of (ẽ5‐C5H5)Fe(CO)2I/P(OMe)3 at −78°C results in 70% yield of the phosphonate complex (ẽ5‐C5H5)Fe(CO)2P(O)(OMe)2 which is an Arbuzov‐like dealkylation product from the cationic intermediate [(ẽ5‐C5H5)Fe(CO)2P(OMe)3+] and the iodide. The amines could assist the Arbuzov‐like dealkylation of [(ẽ5‐C5H5)Fe(CO)2P(OMe)3+] [PF6−] where iron‐carbamoyl intermediates are likely involved in the case of primary amines.
The Mechanism Study on the Catalytic Synthesis of 2,6‐Dimethylphenol from KA‐Oil and Methanol over Magnesium Oxide Catalysts
Authors: Wang Fey‐Long , Tsai Tan‐Feng 
Published: May 2015

AbstractCatalytic synthesis of 2,6‐dimethylphenol from KA‐oil (a mixture of cyclohexanol and cyclohexanone) and methanol was achieved by using magnesium oxide‐supported chromium oxide catalysts in one step. At higher conversion (> 90%), dimethylphenol was formed in high yield (>60 %).The activity of Cr/MgO catalysts depended on the concentration of chromium. The yield of 2,6‐dimethylphenol was also affected by the composition of the ratio of cyclohexanol to cyclohexanone in KA‐oil. Cyclohexanol and cyclohexanone reacting with methanol under the same conditions indicated that pure cyclohexanol or cyclohexanone is less reactive than their mixture, KA‐oil. The adsorption properties of cyclohexanol and cyclohexanone on the surface of Cr/MgO determined by FT‐IR spectroscopy suggest that cyclohexanone is easily reduced to cyclohexanol by the hydrogen which formed in the reaction, and then further reacted with methanol to form 2,6‐dimethyphenol.
Calix[4]arenes with a Lid in their Upper Rims: 1,3‐Dipolar Cycloaddition Reactions of Benzonitrile Oxides with 5‐Allyl‐, 5,11‐Dially‐ and 5,17‐Diallylcalix[4]arenes
Authors: Shu Chun‐Mei , Lin Wei‐Ling , Lee Gene‐Hsiang , Peng Shie‐Ming , Chung Wen‐Sheng 
Published: May 2015

AbstractThe upper rim substituted mono‐ and diisoxazolinomethylcalix[4]arenes 9‐23 are synthesized in good yields from 1,3‐dipolar cycloaddition reactions of papa‐substituted phenyl nitrileoxides with 5‐allyl‐, 5,11‐diallyl‐and 5,17‐diallycalix[4]arenes 5‐7; the structures of 9‐23 are consistent with a ‘cone’ conformation and the ‘vase‐with‐a‐lid’ structure of 11 was confirmed by a single‐crystal x‐ray analysis. Preliminary results show that the monoisoxazolinomethylcalix[4] arene can form an inclusion complex with ammonium cation.
Nonsteroidal Constituents from Solanum Incanum L.
Authors: Lin Yun‐Lian , Wang Wan‐Yi , Kuo Yueh‐Hsiung , Chen Chieh‐Fu 
Published: May 2015

AbstractSixteen compounds were isolated from the aerial parts of Solanum incanum L. These compounds included ten flavonoids (1‐10), chlorogenic acid (11), adenosine (12), benzyl‐O‐β‐D‐xylopyranosyl(1→2)‐β‐D‐glucopyranoside (13), and three phenylalkanoic acids (14‐16). The structures were determined from their physical and spectral data. Among these compounds, kaempferol 3‐O‐(6″′‐O‐2,5‐dihydroxycinnamoyl)‐β‐D‐glucopyranosyl (1→2) β‐D‐glucopyranoside (10) was identified as a new compound.
Efficient Synthesis of Alkyl End‐Capped Oligoheterocycles via the Use of Palladacycle Catalyst
Authors: Luo Fen‐Tair , Bajji Ashok C. 
Published: May 2015

AbstractThe preparation of mixed thiophene/furan oligomers with alkyl groups at α,α′‐position by the method which we discovered recently in our lab is presented. Thus, the mixed thiophene/furan oligomers can be prepared in good yields from monoiodoarene in the presence of 5 mol % of palladacycle catalyst and 1.2 equiv of N,N‐diisopropylethylamine in DMF at 100°C for 8 h.
A Facile Synthesis of Azidoformate via Chloroformate
Authors: Wu Pei‐Lin , Su Chia‐Hao , Gu Yi‐Jeng 
Published: May 2015

AbstractThis work synthesized chloroformates by slowly adding alcohols into a suspension of trichloromethyl chloroformate, instead of phosgene, along with activated charcoal in tetrahydrofuran. This chloroformylation yielded chloroformates in near quantitative yield. The subsequent reaction between chloroformates and sodium azide in dry acetone produced azidoformates in a high yield.
Synthesis of 3‐[5‐methyl‐1‐(4‐methylphenyl)‐1,2,3‐triazol‐4‐yl]‐6‐substituted‐s‐triazolo[3,4‐b]‐1,3,4‐thiadiazoles
Authors: Dong Heng‐Shan , Wei Kun , Wang Qing‐Lian , Quan Bin , Zhang Zi‐Yi 
Published: May 2015

AbstractSeveral 3‐[5‐methyl‐1‐(4‐methylphenyl)‐1,2,3‐triazol‐4‐yl]‐6‐substituted‐1,3,4‐triazolo[3,4‐b]‐1,3,4‐thiadiazoles have been synthesized and the structures of these compounds were established by elemental analysis, MS, IR and 1H NMR spectral data.