bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of efficacy and safety of intracoronary sodium nitroprusside and intravenous adenosine for assessing fractional flow reserve
Authors: Rudzinski Wojciech , Waller Alfonso H. , Rusovici Arthur , Dehnee Abed , Nasur Ali , Benz Michael , Sanchez Salvador , Klapholz Marc , Kaluski Edo 
Published: September 2012

ObjectivesThe purpose of this study was to compare the efficacy and safety of intracoronary (IC) nitroprusside and intravenous adenosine (IVA) for assessing fractional flow reserve (FFR).BackgroundIV infusion of adenosine is a standard method to achieve a coronary hyperemia for FFR measurement. However, adenosine is expensive, causes multiple side effects, and is contraindicated in patients with reactive airway disease. Sodium nitroprusside (NTP) is a strong coronary vasodilator but its efficacy and safety for assessing FFR is not well established.MethodsWe compared FFR response and side effects profile of IC NTP and IVA. Bolus of NTP at a dose of 100 μg and IVA (140 μg/kg/min) were used to achieve coronary hyperemia.ResultsWe evaluated 75 lesions in 53 patients (60% male) mean age 61.6 ± 13.9 years. Mean FFR after NTP was similar to FFR after adenosine (0.836 ± 0.107 vs. 0.856 ± 0.106; P = 0.26; r = 0.91, P < 0.001). NTP induced maximal stable hyperemia within 10 sec (mean: 6.4 ± 1) which lasted consistently between 38 and 60 sec (mean 51 ± 7.5). NTP caused significant (14%), but asymptomatic decrease in mean blood pressure which returned to baseline within 60 sec. Adenosine caused shortness of breath in 26%, headache and flushing in 19%, and transient second degree heart block in 6% of patients. No adverse symptoms were reported after NTP.ConclusionsIC NTP is as effective as IVA for measuring FFR. NTP is better tolerated by patients. Since NTP is inexpensive, readily available, well tolerated, and safe, it may be a better choice for FFR assessment. © 2012 Wiley Periodicals, Inc.
Glycoprotein IIb/IIIa inhibitors with or without thienopyridine pretreatment improve outcomes after primary percutaneous coronary intervention in high‐risk patients with ST elevation myocardial infarction—a meta‐regression of randomized controlled trials
Authors: Sethi Ankur , Bajaj Anurag , Bahekar Amol , Bhuriya Rohit , Singh Mukesh , Ahmed Aziz , Khosla Sandeep 
Published: September 2012

BackgroundRecent studies have casted a doubt on usefulness of routine glycoprotein IIb/IIIA inhibitors (GPI) in patients, pretreated with aspirin and clopidogrel, undergoing primary percutaneous coronary intervention (PCI) for ST elevation myocardial infarction (STEMI).ObjectiveWe aimed to investigate the effect of relevant factors, particularly thienopyridine pretreatment, on clinical benefit from GPI in randomized controlled trials (RCT).MethodsWe searched electronic databases for RCT comparing GPI to control in patients with STEMI undergoing primary PCI. Relevant study covariates and clinical outcomes were extracted. A random effect cumulative and subgroup analyses (thienopyridine non‐pretreated studies vs. pretreated studies) were performed. A weighted random effect meta‐regression to determine the effect of thienopyridine pretreatment, enrollment year, control group mortality, and ischemic time on mortality benefit from GPI use was conducted.ResultsTwenty studies (9 non‐pretreated, 11 pretreated) with a total of 7,414 patients (3,811 GPI, 3,603 control) were included. GPI use reduces mortality (risk ratio, RR = 0.75 95% confidence interval (CI) 0.57–0.97, P = 0.03), target vessel revascularization (TVR) (RR = 0.63, 95% CI 0.50–0.80, P = 0.0002), but not reinfarction (RR = 0.66, 95% CI 0.44–1.0, P = 0.05) at 30 days. There was no effect of thienopyridine pretreatment on reduction in mortality (P = 0.39), reinfarction (P =0.46), or TVR (P =0.95) in subgroup analysis. Meta‐regression analyses showed significant effect of control group mortality risk (B = −12.15, P = 0.034) but not of thienopyridine pretreatment, enrollment year or control group ischemic time on mortality reduction from GPI use.ConclusionThe benefit from GPI use in primary PCI for STEMI appears to depend on mortality risk, and not on thienopyridine pretreatment. © 2013 Wiley Periodicals, Inc.
High Throughput Screening of a Catalyst Library for the Asymmetric Transfer Hydrogenation of Heteroaromatic Ketones: Formal Syntheses of (R)‐Fluoxetine and (S)‐Duloxetine
Authors: Buitrago Elina , Lundberg Helena , Andersson Hans , Ryberg Per , Adolfsson Hans 
Published: September 2012

AbstractA total of 21 amino acid based ligands including hydroxy amide, thioamide, and hydroxamic acid functionalities, respectively, were combined with [Ru(p‐cymene)Cl2]2 and [RhCp*Cl2]2, and used as catalysts for the asymmetric transfer hydrogenation of four different heteroaromatic ketones in 2‐propanol. The reactions were performed on a Chemspeed automated high‐throughput screening robotic platform. Optimal catalysts were identified for the individual heterocyclic substrate classes. Based on these results, the formal syntheses of the antidepressant drugs (R)‐fluoxetine and (S)‐duloxetine were conducted by using the found catalysts in the key reaction step, which results in high isolated yields (94 %) and excellent product enantioselectivities (>99 % ee) of the formed 1,3‐amino alcohols.
Stereoselective Iodolactonization of 4‐Allenoic Acids with Efficient Chirality Transfer: Development of a New Electrophilic Iodination Reagent
Authors: Zhang Xiaobing , Fu Chunling , Yu Yihua , Ma Shengming 
Published: September 2012

AbstractA highly stereoselective iodolactonization of 4‐allenoic acids with a new sterically demanding electrophilic iodination reagent to afford optically active γ‐butyrolactones has been developed. The reaction shows high efficiency of axial chirality transfer and excellent Z/E selectivity and has been applied to the synthesis of chiral cis‐β,γ‐disubstituted γ‐butyrolactones to give very high diastereomeric and enantiomeric excess values. The reaction has been successfully utilized in the synthesis of naturally occurring compounds (+)‐cis‐whisky lactone and (+)‐cis‐3‐methyl‐4‐decanolide.
Artificial Signal Transduction with Primary and Secondary Messengers
Authors: Bernitzki Kai , Maue Michael , Schrader Thomas 
Published: September 2012

AbstractThe complete, entirely artificial, signal‐transduction process was realized with a pair of tailored transmembrane units that were equipped with receptor‐ and reactive sites at both amphiphilic ends. Thus, docking of the primary messenger, transmission of the signal, and release of the secondary messenger could all be imitated in a single experimental setup. The system imitates the signaling principle of receptor tyrosine kinases and employs bisphosphonate head‐groups for oligoamine‐recognition and a pair of thiol nucleophiles and pyridine disulfide tail‐groups for intravesicle SN2 displacement. This system operates in a unidirectional fashion, does not suffer from intervesicle competition, and is highly sensitive towards the lipid composition of the membrane and the nature of the primary messenger.
Supramolecular Chirality in Organo‐, Hydro‐, and Metallogels Derived from Bis‐amides of L‐(+)‐Tartaric Acid: Formation of Highly Aligned 1D Silica Fibers and Evidence of 5‐c Net SnS Topology in a Metallogel Network
Authors: Das Uttam Kumar , Dastidar Parthasarathi 
Published: September 2012

AbstractA series of bis‐amides derived from L‐(+)‐tartaric acid was synthesized as potential low‐molecular‐weight gelators. Out of 14 bis‐amides synthesized, 13 displayed organo‐, hydro‐, and ambidextrous gelation behavior. The gels were characterized by methods including circular dichroism, differential scanning calorimetry, optical and electron microscopy, and rheology. One of the gels derived from di‐3‐pyridyltartaramide (D‐3‐PyTA) displayed intriguing nanotubular morphology of the gel network, which was exploited as a template to generate highly aligned 1D silica fibers. The gelator D‐3‐PyTA was also exploited to generate metallogels by treatment with various CuII/ZnII salts under suitable conditions. A structure–property correlation on the basis of single‐crystal and powder X‐ray diffraction data was attempted to gain insight into the structures of the gel networks in both organo‐ and metallogels. Such study led to the determination of the gel‐network structure of the CuII coordination‐polymer‐based metallogel, which displayed a 2D sheet architecture made of a chloride‐bridged double helix that resembled a 5‐c net SnS topology.
Synthesis of Rhenium‐Centric Reverse Turn Mimics
Authors: Hickey Jennifer L. , Luyt Leonard G. 
Published: September 2012

AbstractMolecular scaffolds have been shown to facilitate and stabilise secondary structural turn elements, with a central core‐arranging functionality in a defined three‐dimensional orientation. In a peptide‐based molecular imaging probe, this approach is of particular value as it would essentially “hide” a metal radioisotope within the ligand framework, making the labelling element a critical component of the receptor‐bound structure. Starting from a 1,2‐diaminoethane loaded 2‐chlorotrityl resin, a versatile set of triamine ligand systems were synthesised by using solid‐phase Fmoc‐based peptide chemistry. The resultant resin‐bound peptides then underwent amide reduction by treatment with borane‐THF at 65 °C. This provided complete conversion to the corresponding polyamine entities in high purity for the majority of the amino acids utilised. The triamines were then coordinated on solid support by using [NEt4]2[Re(CO)3(Br)3] followed by resin cleavage and HPLC purification, to give the desired rhenium coordinated species. We have shown that amino acid sequences can be assembled, reduced and coordinated on‐resin, resulting in a versatile set of metal–ligand constructs. These studies could be expanded to generate libraries of turn‐based peptidomimetics containing Re/TcI organometallic scaffolds, with the intention of developing an improved approach for finding new diagnostic and therapeutic radiopharmaceutical entities.
Platinum Nanoparticles Stabilized by Cucurbit[6]uril with Enhanced Catalytic Activity and Excellent Poisoning Tolerance for Methanol Electrooxidation
Authors: Cao Minna , Wu Dongshuang , Gao Shuiying , Cao Rong 
Published: September 2012

AbstractThree sub‐10 nm platinum nanoparticles (PtNPs) with distinctive morphologies were developed by using cucurbit[6]uril (CB[6]) as stabilizing agent and support. Both the size and shape of the PtNPs were simultaneously controlled by tuning the reducing agents. The prepared NPs have been comprehensively characterized by X‐ray diffraction, X‐ray photoelectron spectroscopy, transmission electron microscopy, and cyclic voltammetry. On account of the presence of CB[6] and its unique structural features, the as‐prepared PtNPs are homogeneous in morphologies and exhibit higher activities toward methanol electrooxidation than commercial Pt/C. CB[6] has the ability to bind small molecules that can promote CO oxidation, therefore, all the three PtNPs showed enhanced poisoning tolerance. Such unique abilities of CB[6] can even promote the poisoning tolerance of commercial Pt/C through simple physical mixing.
Inverting the Regioselectivity of the Berberine Bridge Enzyme by Employing Customized Fluorine‐Containing Substrates
Authors: Resch Verena , Lechner Horst , Schrittwieser Joerg H. , Wallner Silvia , Gruber Karl , Macheroux Peter , Kroutil Wolfgang 
Published: September 2012

AbstractFluorine is commonly applied in pharmaceuticals to block the degradation of bioactive compounds at a specific site of the molecule. Blocking of the reaction center of the enzyme‐catalyzed ring closure of 1,2,3,4‐tetrahydrobenzylisoquinolines by a fluoro moiety allowed redirecting the berberine bridge enzyme (BBE)‐catalyzed transformation of these compounds to give the formation of an alternative regioisomeric product namely 11‐hydroxy‐functionalized tetrahydroprotoberberines instead of the commonly formed 9‐hydroxy‐functionalized products. Alternative strategies to change the regioselectivity of the enzyme, such as protein engineering, were not applicable in this special case due to missing substrate–enzyme interactions. Medium engineering, as another possible strategy, had clear influence on the regioselectivity of the reaction pathway, but did not lead to perfect selectivity. Thus, only substrate tuning by introducing a fluoro moiety at one potential reactive carbon center switched the reaction to the formation of exclusively one regioisomer with perfect enantioselectivity.
ChemInform Abstract: Synthesis and Thermoelectric Properties of the Novel A‐Site Deficient Zn0.5Rh2O4 Compound.
Authors: Nakamura Yuta , Kakemoto Hirofumi , Nishiyama Shin , Irie Hiroshi 
Published: September 2012

AbstractThe new thermoelectric title material is obtained from Li0.5Zn0.5Rh2O4 (obtained by solid state reaction of Li2CO3, Rh2O3, and ZnO in air at 1000 °C for 24 h) by immersion into an aqueous solution of K2S2O8 (1 and 10 d).
ChemInform Abstract: Unconventional Colossal Magnetoresistance in Sodium Chromium Oxide with a Mixed‐Valence State.
Authors: Sakurai Hiroya , Kolodiazhnyi Taras , Michiue Yuichi , Takayama‐Muromachi Eiji , Tanabe Yuichi , Kikuchi Hikomitsu 
Published: September 2012

AbstractThe new CrIII/CrIV mixed‐valence compound NaCr2O4 is synthesized by high temperature/high pressure reaction of a stoichiometric mixture of NaCrO2, Cr2O3, and CrO3 (gold capsule, Ar, 7 GPa, 1300 °C, 6 h).
ChemInform Abstract: Asymmetric Phase Transfer Darzens Reactions Catalyzed by D‐Glucose‐ and D‐Mannose‐Based Chiral Crown Ethers.
Authors: Rapi Zsolt , Bako Peter , Keglevich Gyoergy , Szoelloesy Aron , Drahos Laszlo , Botyanszki Adrienn , Holczbauer Tamas 
Published: September 2012

AbstractAsymmetric Darzens condensation of various α‐chloro ketones with aromatic aldehydes proceeds readily in the presence of a D‐glucose‐derived chiral crown ether under mild conditions.
ChemInform Abstract: N‐Alkylation of Tosylamides Using Esters as Primary and Tertiary Alkyl Sources: Mediated by Hydrosilanes Activated by a Ruthenium Catalyst.
Authors: Nishikata Takashi , Nagashima Hideo 
Published: September 2012

AbstractThe selective introductions of both primary and tertiary alkyl groups to tosylamides are achieved by simply changing the hydrosilane and the alkyl ester group.
ChemInform Abstract: Copper‐Catalyzed Formation of C—O Bonds by Direct α‐C—H Bond Activation of Ethers Using Stoichiometric Amounts of Peroxide in Batch and Continuous‐Flow Formats.
Authors: Kumar G. Sathish , Pieber Bartholomaeus , Reddy K. Rajender , Kappe C. Oliver 
Published: September 2012

AbstractThe formation of unsymmetrical acetals is smoothly achieved using the title Cu‐catalyzed etherification of cyclic ethers (II), (IV) or dimethoxyethane (VI) with phenols (I) or β‐keto esters (IX).
ChemInform Abstract: PdCl2‐Catalyzed Oxidative Cycloisomerization of 3‐Cyclopropylideneprop‐2‐en‐1‐ones.
Authors: Miao Maozhong , Cao Jian , Zhang Jingjing , Huang Xian , Wu Luling 
Published: September 2012

AbstractReaction in the presence of Dess—Martin periodinane affords functionalized 2‐alkylidenecyclobutanones which are further converted to furanones bearing a spirocyclopropyl‐group if TfOH is used as a catalyst.
ChemInform Abstract: Formal [4 + 1]‐ and [5 + 1]‐Annulation by an SN2—Conjugate Addition Sequence: Stereoselective Synthesis of Highly Substituted Carbocycles.
Authors: Tong Benny Meng Kiat , Chen Hui , Chong Sin Yee , Heng Yi Li , Chiba Shunsuke 
Published: September 2012

AbstractThe reaction of 6‐bromo‐2‐hexenoates with active methylene compounds proceeds via formal [4 + 1]‐annulation and affords highly functionalized cyclopentanes with up to 4 stereocenters.
ChemInform Abstract: Selective N‐Alkylation of Arylamines with Alkyl Chloride in Ionic Liquids: Scope and Applications.
Authors: Monopoli Antonio , Cotugno Pietro , Cortese Marina , Calvano Cosima Damiana , Ciminale Francesco , Nacci Angelo 
Published: September 2012

AbstractThe synthetic value of the present protocol is demonstrated by preparation of bioactive heterocycles, e.g. (VI), and MALDI matrix (VIII).
ChemInform Abstract: New Synthetic Approach to Phenylmethanesulfonamide Derivatives on the Basis of Phenyl‐N‐(2,2,2‐trichloroethylidene)methanesulfonamide.
Authors: Aizina Yu. A. , Levkovskaya G. G. , Rozentsveig I. B. 
Published: September 2012

AbstractA new representative of highly electrophilic electron‐deficient imines, title compound (IV), is synthesized which shows high reactivity in the alkylation of arenes (VI).
ChemInform Abstract: Palladium‐Catalyzed Suzuki Couplings Using a Novel Diaminophosphine Oxide as Ligand.
Authors: Mai Wen Peng , Wang Hui Hui , Yuan Jin Wei , Yang Liang Ru , Li Zhi Cheng 
Published: September 2012

AbstractThe stereochemically congested ligand PAT is synthesized and successfully employed in coupling reactions of aryl bromides with arylboronic acids.
ChemInform Abstract: General and Selective Head‐to‐Head Dimerization of Terminal Alkynes Proceeding via Hydropalladation Pathway.
Authors: Jahier Claire , Zatolochnaya Olga V. , Zvyagintsev Nickolay V. , Ananikov Valentine P. , Gevorgyan Vladimir 
Published: September 2012

AbstractAromatic, heteroaromatic and aliphatic alkynes, bearing a wide range of functional groups can be applied.
ChemInform Abstract: Trichlorosilyl Triflate Mediated Enantioselective Directed Cross‐Aldol Reaction Between Ketones Using a Chiral Phosphine Oxide as an Organocatalyst.
Authors: Aoki Shohei , Kotani Shunsuke , Sugiura Masaharu , Nakajima Makoto 
Published: September 2012

AbstractFor the first time, the title reaction between simple ketones is presented.
ChemInform Abstract: Influence of the Acetylenic Substituent on the Intramolecular Carbolithiation of Alkynes.
Authors: Girard Anne‐Lise , Lhermet Rudy , Fressigne Catherine , Durandetti Muriel , Maddaluno Jacques 
Published: September 2012

AbstractCyclization of (2‐iodophenyl)propargyl ethers by carbolithiation occurs when the terminal propargylic carbon atom is at least disubstituted and bears a coordinating functionality.
ChemInform Abstract: An Efficient Pyrroline Annulation of Glycine Imine with Enones.
Authors: Zhang Yu , Pan Ling , Xu Xianxu , Liu Qun 
Published: September 2012

AbstractMichael addition of N‐(p‐chlorobenzylidene)glycine methyl ester (II) with various enones is combined with cyclization during the workup on silica gel column chromatography to give polysubstituted pyrrolines (III)/(IV), (VI)/(VII) and (IX)/(X) as diastereomeric mixtures.
ChemInform Abstract: The Synthesis of N‐Heterocycles via Copper/TEMPO Catalyzed Aerobic Oxidation of Amino Alcohols.
Authors: Flanagan James C. A. , Dornan Laura M. , McLaughlin Mark G. , McCreanor Niall G. , Cook Matthew J. , Muldoon Mark J. 
Published: September 2012

AbstractThe copper‐catalyzed aerobic oxidation of 2‐aminophenethyl alcohols (I) leads selectively to indoles (II), whilst the analogous reaction of alcohols (III) gives rise to a mixture of quinolines (IV) and tetrahydroquinolinones (V).
ChemInform Abstract: Silver Triflate Catalyzed Tandem Heterocyclization/Alkynylation of 1‐((2‐Tosylamino)aryl)but‐2‐yne‐1,4‐diols to 2‐Alkynyl Indoles.
Authors: Mothe Srinivasa Reddy , Kothandaraman Prasath , Lauw Sherman Jun Liang , Chin Samuel Ming Wei , Chan Philip Wai Hong 
Published: September 2012

AbstractThe environmentally benign silver‐catalyzed tandem heterocyclization—alkynylation reaction tolerates a diversity of substituents at the starting alkyne‐1,4‐diols.
ChemInform Abstract: N‐Heterocyclic Carbene (NHC)‐Catalyzed Highly Diastereo‐ and Enantioselective Oxo‐Diels—Alder Reactions for Synthesis of Fused Pyrano[2,3‐b]indoles.
Authors: Yang Limin , Wang Fei , Chua Pei Juan , Lv Yunbo , Zhong Liang‐Jun , Zhong Guofu 
Published: September 2012

AbstractThe reaction proceeds with complete dia‐ and excellent enantioselectivity and tolerates N‐produced N‐unprotected oxoindole derivatives and a wide range of functional groups in the α‐chloroaldehydes.
ChemInform Abstract: One‐Pot Regioselective Synthesis of 1,4,5‐Trisubstituted Pyrazoles under Solvent‐Free Conditions Without Catalyst.
Authors: Alinezhad Heshmatollah , Tajbakhsh Mahmood , Zare Mahboobeh 
Published: September 2012

AbstractThe title pyrazoles (IV) are prepared by a very fast one‐pot reaction.
ChemInform Abstract: Stereoselective Palladium‐Catalyzed Functionalization of Homoallylic Alcohols: A Convenient Synthesis of Di‐ and Trisubstituted Isoxazolidines and β‐Amino‐δ‐Hydroxy Esters.
Authors: Malkov Andrei V. , Barlog Maciej , Miller‐Potucka Lucie , Kabeshov Mikhail A. , Farrugia Louis J. , Kocovsky Pavel 
Published: September 2012

AbstractN‐Boc‐protected alkyloxyamines derived from homoallylic alcohols undergo a diastereoselective Pd‐catalyzed ring‐closing carbonylative amidation reaction to afford isoxazolidines that can be readily converted into N‐Boc‐protected β‐amino‐δ‐hydroxy carboxylic acid esters by cleavage of the O—N bond with Mo(CO)6.
ChemInform Abstract: Copper(II)‐Catalyzed Aerobic Oxidative Synthesis of Substituted 1,2,3‐ and 1,2,4‐Triazoles from Bisarylhydrazones via C—H Functionalization/C—C/N—N/C—N Bonds Formation.
Authors: Guru Murali Mohan , Punniyamurthy Tharmalingam 
Published: September 2012

AbstractA new, selective, and widely applicable method is reported.
ChemInform Abstract: Enantioselective Synthesis of Substituted Pyrans via Amine‐Catalyzed Michael Addition and Subsequent Enolization/Cyclization.
Authors: Das Utpal , Huang Chan‐Hui , Lin Wenwei 
Published: September 2012

AbstractThe Michael addition—cyclization sequence of alkenes (I) with cyclohexanone proceeds with high stereoselectivity in the presence of a Chinchona‐based primary amine and o‐fluorobenzoic acid.
ChemInform Abstract: K2CO3‐Catalyzed Synthesis of Chromones and 4‐Quinolones Through the Cleavage of Aromatic C—O Bonds.
Authors: Zhao Jie , Zhao Yufen , Fu Hua 
Published: September 2012

AbstractThe intramolecular cyclization is catalyzed by K2CO3 and tolerates a wide range of functionalities and aromatic or aliphatic substituents at the dione moiety.
ChemInform Abstract: Solvent‐Free One‐Pot Synthesis of 2‐Pyridone Derivatives.
Authors: Hossaini Zinatossadat , Rostani‐Charati Faramarz , Hajinasiri Rahimeh , Khalilzadeh Mohammad A. 
Published: September 2012

AbstractA simple protocol is presented for successful construction of the biologically important framework.
ChemInform Abstract: Solvent Effect on Copper‐Catalyzed Azide—Alkyne Cycloaddition (CuAAC): Synthesis of Novel Triazolyl Substituted Quinolines as Potential Anticancer Agents.
Authors: Pal Manojit , et al. et al. 
Published: September 2012

Abstract14 Title compounds of type (III) or (IV) are prepared.
ChemInform Abstract: Enantioselective Diynylation of Cyclic N‐Acyl Ketimines: Access to Chiral Trifluoromethylated Tertiary Carbinamines.
Authors: Zhang Fa‐Guang , Ma Hai , Nie Jing , Zheng Yan , Gao Qingzhi , Ma Jun‐An 
Published: September 2012

AbstractThe reaction proceeds well using a chiral chloramphenicol‐amine derivative as catalyst.
ChemInform Abstract: Cycloaddition/Aromatization Sequence for the Synthesis of 2,3‐Disubstituted Benzenephosphonates.
Authors: Villemin Elise , Marchand‐Brynaert Jacqueline 
Published: September 2012

AbstractDiels—Alder reaction of diene (II) with dienophiles (I) or (VI) and subsequent treatment of the resulting cycloadducts according to A) gives ortho‐phosphonated phthalic acid derivatives.
ChemInform Abstract: Synthesis and Antitumor‐Evaluation of 1,3,4‐Thiadiazole‐Containing Benzisoselenazolone Derivatives.
Authors: Luo Zhenhua , Chen Baoquan , He Shuangyan , Shi Yanping , Liu Yuming , Li Caiwen 
Published: September 2012

AbstractA series of novel N‐thiadiazolylbenzisoselenazolone derivatives (VI) (I5 examples) is synthesized and evaluated for in vitro antiproliferative activity against 3 different human tumor cell lines.
ChemInform Abstract: Cyclohexadepsipeptides from the Filamentous Fungus Acremonium sp. BCC 2629.
Authors: Bunyapaiboonszi Taridaporn , Vongvilai Pornrapee , Auncharoen Patchanee , Isaka Masahiko 
Published: September 2012

AbstractBeauvenniatins F (Ia), G1 (Ib), G2 (Ic), G3 (Id), H1 (Ie), H2 (If) and H3 (Ig) are isolated together with known cyclopeptides and identified as new constituents.