bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Olefin Preparation via Palladium‐Catalyzed Oxidative De‐Azotative and De‐Sulfitative Internal Cross‐Coupling of Sulfonylhydrazones.
Authors: Tan Hongyu , Houpis Ioannis , Liu Renmao , Wang Youchu , Chen Zhilong 
Published: October 2015

AbstractHighly substituted aromatic olefins are obtained by a new, effective, and atom‐economical intramolecular cross‐coupling reaction of the corresponding electron‐rich aromatic sulfonylhydrazones involving a formal extrusion of SO2 and N2.
ChemInform Abstract: A Nano Tetraimine Pd(0) Complex: Synthesis, Characterization, Computational Studies and Catalytic Applications in the Heck—Mizoroki Reaction in Water.
Authors: Mandegani Zeinab , Asadi Mozaffar , Asadi Zahra , Mohajeri Afshan , Iranpoor Nasser , Omidvar Akbar 
Published: October 2015

AbstractA newly synthesized nano tetraimine Pd(0) complex (PTIC) is used as an efficient catalyst in Heck—Mizoroki reactions to afford a series of (het)aryl alkenes.
ChemInform Abstract: A Detachable Ester Bond Enables Perfect Z‐Alkylations of Olefins for the Synthesis of Tri‐ and Tetrasubstituted Alkenes.
Authors: Nishikata Takashi , Nakamura Kimiaki , Inoue Yuki , Ishikawa Shingo 
Published: October 2015

AbstractThe esterification‐alkylation reaction of vinyl phenols (I) with bromides (II) gives rise to lactones (III), which are converted into Z‐alkylated styrenes (IV) after hydrolysis.
ChemInform Abstract: A Bimetallic Iridium(II) Catalyst: [{Ir(IDipp)(H)}2][BF4]2 (IDipp = 1,3‐bis(2,6‐diisopropylphenylimidazol‐2‐ylidene))
Authors: Rubio‐Perez Laura , Iglesias Manuel , Munarriz Julen , Polo Victor , Sanz Miguel Pablo J. , Perez‐Torrente Jesus J. , Oro Luis A. 
Published: October 2015

Abstractis used for the hydroalkynylation of imines
ChemInform Abstract: The Coupling Reactions of Aryl Halides and Phenols Catalyzed by Palladium and MOP‐Type Ligands.
Authors: Zhang Yi , Ni Gang , Li Chengjun , Xu Sheng , Zhang Zhaoguo , Xie Xiaomin 
Published: October 2015

AbstractOptimized reactions conditions are developed for the Pd‐catalyzed coupling of aryl halides and phenols.
ChemInform Abstract: Rhodium‐Catalyzed Synthesis of Aryl Ketones from Carboxylic Acid Anhydrides and Potassium Aryltrifluoroborates in the Presence of CuI.
Authors: Liu Xia , Yi Ze , Yi Maocong , Wang Jianhui , Liu Guiyan 
Published: October 2015

AbstractAliphatic carboxylic anhydrides do not react with potassium phenyltrifluoroborate under the reaction conditions.
ChemInform Abstract: Metal Free Sulfenylation of Active Methylene Compounds and Indole: TBATB Mediated Synthesis.
Authors: Rahaman Rajjakfur , Devi Namita , Barman Pranjit 
Published: October 2015

AbstractVarious diaryldisulfides as well as diethyldisulfide are used as sulfenylating agents according to the title reaction providing the products in high yields.
ChemInform Abstract: Di‐ and Tri‐Nuclear‐Palladium Complexes Bearing Piperidoimidazolin‐2‐ylidenes: Synthesis, Characterization, and Catalytic Applications.
Authors: Tuerkmen Guelsah , Atik Aylin , Sahin Zarife Sibel , Tuerkmen Hayati 
Published: October 2015

AbstractA trinuclear palladium N‐heterocyclic carbene complex is found to efficiently catalyze Heck‐coupling reactions of styrene with aryl bromides and Suzuki—Miyaura couplings of phenylboronic acid with aryl chlorides.
ChemInform Abstract: Gold(I)‐Catalyzed Selective Heterocyclization of Propargylic Thioureas: Mechanistic Study of Competitive Gold‐Activation Mode.
Authors: Jiang Yu , Wei Yin , Tang Xiang‐Ying , Shi Min 
Published: October 2015

AbstractA new selective gold(I)‐catalyzed intramolecular heterocyclization of homopropargylic isothiocyanates, erroneously named propargylic thioureas, is developed, efficiently affording two kinds of cycloadducts in moderate to excellent yields with a broad substrate scope.
ChemInform Abstract: Phosphine‐Catalyzed Diastereoselective Synthesis of β‐Lactones from Disubstituted Ketenes and α‐Chiral Oxyaldehydes.
Authors: Mondal Mukulesh , Chen Shi , Othman Nabil , Wheeler Kraig A. , Kerrigan Nessan J. 
Published: October 2015

AbstractCyclization of ketenes with glyceraldehyde acetonides gives β‐lactones diastereoselectively.
ChemInform Abstract: An Unexpected Thermal [1,3]‐[1,3]‐para Rearrangement of Chromone‐3‐ylmethyl Aryl Ethers: Mechanism and Application of the Intercepted [1,3]‐Rearranged Intermediates to the Synthesis of cis‐Homopterocarpans.
Authors: Devarajan Krishnan , Devaraj Somasundaram , Balasubramanian Kalpattu K , Bhagavathy Shanmugasundaram 
Published: October 2015

AbstractChromone‐3‐ylmethyl aryl ethers (I) undergo a novel domino [1,3]‐[1,3]‐rearrangement to give 4′‐hydroxyhomoisoflavones (II) under thermal conditions whereas, the para‐substituted ethers (IV) lead to 2′‐hydroxyhomoisoflavones instead of the expected Claisen rearrangement.
ChemInform Abstract: Highly Efficient Regioselective Synthesis of Pyrroles via a Tandem Enamine Formation—Michael Addition—Cyclization Sequence under Catalyst‐ and Solvent‐Free Conditions.
Authors: Vivekanand Thavaraj , Vinoth Perumal , Agieshkumar B. , Sampath Natarajan , Sudalai Arumugam , Menendez J. Carlos , Sridharan Vellaisamy 
Published: October 2015

AbstractA convenient catalyst‐free, three‐component procedure is developed for the synthesis of tetrasubstituted pyrroles under solvent‐free conditions and in green solvents glycerol, PEG‐200 and water.
ChemInform Abstract: “On Water” Direct Catalytic Vinylogous Henry (Nitroaldol) Reactions of Isatins for the Efficient Synthesis of Isoxazole Substituted 3‐Hydroxyindolin‐2‐ones.
Authors: Zhang Yong , Wei Biao‐Wen , Lin Hui , Zhang Ling , Liu Jin‐Xiang , Luo Hai‐Qing , Fan Xiao‐Lin 
Published: October 2015

AbstractA highly efficient and environmentally benign access to medicinally important isoxazole‐substituted 3‐hydroxy‐2‐oxindole derivatives by a new direct vinylogous Henry addition of dialkyl‐4‐nitroisoxazoles to isatins is described.
ChemInform Abstract: Enantioselective Synthesis of 3‐Fluoro‐3‐allyl‐oxindoles via Phosphine‐Catalyzed Asymmetric γ‐Addition of 3‐Fluoro‐oxindoles to 2,3‐Butadienoates.
Authors: Wang Tianli , Hoon Ding Long , Lu Yixin 
Published: October 2015

AbstractThe addition product can be easily converted into the 3‐allyl substituted oxindole derivative (V).
ChemInform Abstract: Catalytic Intramolecular Decarbonylative Coupling of 3‐Aminocyclobutenones and Alkenes: A Unique Approach to [3.1.0] Bicycles.
Authors: Zhou Xuan , Zafar Imran , Dong Guangbin 
Published: October 2015

AbstractN‐but‐2‐enyl‐ and N‐but‐3‐enyl‐substituted substrates do not give the desired product.
ChemInform Abstract: Iron‐Catalyzed Diastereoselective Intramolecular Olefin Aminobromination with Bromide Ion.
Authors: Tian Jun‐Shan , Zhu Cheng‐Liang , Chen Yun‐Rong , Xu Hao 
Published: October 2015

AbstractThe new method is suitable for both internal and terminal olefins and provides a convenient approach to vicinal bromo primary amines.
ChemInform Abstract: Microwave Assisted Azide—Alkyne Cycloaddition Reaction Using Polymer Supported Cu(I) as a Catalytic Species: A Solventless Approach.
Authors: Taher Abu , Nandi Debkumar , Islam Rafique Ul , Choudhary Meenakshi , Mallick Kaushik 
Published: October 2015

AbstractNewly synthesized polymer supported copper(I) composite is used as an effective catalyst for a 1,3‐dipolar cycloaddition reaction between terminal alkynes and azides to synthesize 1,2,3‐triazoles with excellent yields using a microwave irradiation technique in the absence of any solvent.
ChemInform Abstract: Gold‐Catalyzed Selective Oxidation of 4‐Oxahepta‐1,6‐diynes to 2H‐Pyran‐3(6H)‐ones and Chromen‐3(4H)‐ones via β‐Gold Vinyl Cation Intermediates.
Authors: Ji Kegong , Liu Xiang , Du Bowen , Yang Fang , Gao Jinming 
Published: October 2015

AbstractThe title reaction leads to pyranones (II), and benzochromenones (IV) in the presence of 2 mol% catalyst loading.
ChemInform Abstract: Carbonyl Olefination of Diaryl Ketones with Heteroaryl Sulfoxides.
Authors: Gao Bing , Hu Jingyu , Zhao Yanchuan , Hu Jinbo 
Published: October 2015

AbstractHitherto unknown Julia—Kocienski type olefination reactions of 2‐pyridyl sulfoxides and 1,3‐benzothiazol‐2‐yl sulfoxides are described.
ChemInform Abstract: Organocatalytic Asymmetric Intramolecular aza‐Henry Reaction: Facile Synthesis of trans‐2,3‐Disubstituted Tetrahydroquinolines.
Authors: Maity Rajendra , Pan Subhas Chandra 
Published: October 2015

AbstractThe products are obtained in high yields and with moderate enantioselectivities with the latter being significantly improved by recrystallization.
ChemInform Abstract: Single Step Incorporation of Carboxylic Acid Groups in the Lower Rim of Calix[4]arenes: A Recyclable Catalyst Towards Assembly of Diverse Five Ring Fused Acridines.
Authors: Sarkar Piyali , Mukhopadhyay Chhanda 
Published: October 2015

AbstractNew calix[4]arene grafted tricarboxylic acid is employed as an recyclable organocatalyst for the environmentally benign synthesis of substituted five ring‐fused acridine derivatives by the reaction of isatins with dimedone, alkyl/aryl amines, and diethyl acetylenedicarboxylate in PEG/H2O.
ChemInform Abstract: Efficient Approach to Mesoionic Triazolo[5,1‐a]isoquinolium Through Rhodium‐Catalyzed Annulation of Triazoles and Internal Alkynes.
Authors: Zhao Shixian , Yu Ruicheng , Chen Wanzhi , Liu Miaochang , Wu Huayue 
Published: October 2015

AbstractDepending on the additive, 4‐aryltriazoles (I) are either annelated to the title compounds or vinylated at both ortho positions of the arene moiety relative to the triazole residue.
ChemInform Abstract: Synthesis of gem‐Bis‐phosphonates with (3‐Aryl‐4,5‐dihydroisoxazol‐5‐yl)methylamino Moiety.
Authors: Brel Valery K. 
Published: October 2015

AbstractTitle compounds (VI) with two pharmacophore sites, aminomethylene 1,1‐bisphosphonate fragment and 3‐arylisoxazoline moiety, are synthesized in good yields by a simple method.
ChemInform Abstract: Palladium‐Catalyzed Oxidative Synthesis of Highly Functionalized Ortholactones.
Authors: Baddeley Kate L. , Cao Qun , Muldoon Mark J. , Cook Matthew J. 
Published: October 2015

AbstractA palladium‐catalyzed oxidative reaction is reported which converts dihydropyrans to their corresponding ortholactone.
ChemInform Abstract: Direct Staudinger—Phosphonite Reaction Provides Methylphosphonamidates as Inhibitors of CE4 De‐N‐Acetylases.
Authors: Ariyakumaran Rishikesh , Pokrovskaya Varvara , Little Dustin J. , Howell P. Lynne , Nitz Mark 
Published: October 2015

Abstract6 examples
ChemInform Abstract: A New Indole Alkaloid from Cleome droserifolia.
Authors: Hussain Javid , Khan Hidayatullah , Ali Liaqat , Latif Khan Abdul , Ur Rehman Najeeb , Jahangir Sajid , Al‐Harrasi Ahmed 
Published: October 2015

AbstractThe title compound (I) appears to be a potent urease inhibitor.
ChemInform Abstract: Chemical Constituents of Anisodus luridus Roots and Their Antimicrobial Screening.
Authors: Verma Mradul , Lal Das Lalit Kumar , Gangwar Mayank , Sahai Mahendra , Nath Gopal , Singh Tryambak Deo 
Published: October 2015

AbstractFirst time, potentially antimicrobial alkaloids β‐sitosterol, esculetin, β‐sitosterol‐β‐D‐glucoside, apohyoscyamine, and hyoscyamine are isolated from the methanolic extract of roots of Anisodus luridus.
ChemInform Abstract: Three New Coumarins from Saposhnikovia divaricata and Their Porcine Epidemic Diarrhea Virus (PEDV) Inhibitory Activity.
Authors: Yang Jun‐Li , Dhodary Basanta , Quy Ha Thi Kim , Kim Jinwoong , Kim Eunhee , Oh Won Keun 
Published: October 2015

AbstractThe new compounds (I)‐(III) show moderate inhibitory activity against PEDV in a dose‐dependent manner without any cytotoxicity.
ChemInform Abstract: Nickel Hexacyanoferrate as Suitable Alternative to Ag for Electrochemical Lithium Recovery.
Authors: Trocoli R. , Battistel A. , La Mantia F. 
Published: October 2015

AbstractKNiFe(CN)6 with the Prussian blue structure precipitates from aqueous solutions of Ni(NO3)2 and K3Fe(CN)6 (sonication, 70 °C, 30 min).
ChemInform Abstract: Synthesis and Biological Activity of (γ‐Arylpyridino)‐dibenzoaza‐14‐crown‐4 Ethers.
Authors: Le Tuan Anh , Truong Hieu Hong , Thi Thanh Phoung Nguyen , Thi Nhung Dao , To Hai Tung , Thi Ha Pham , Soldatenkov Anatoly T. 
Published: October 2015

AbstractTitle compounds (III) are easily synthesized in one step.
ChemInform Abstract: Chemical Vapor Deposition of Monolayer Rhenium Disulfide (ReS2).
Authors: Tiwary Chandra Sekhar , et al.  
Published: October 2015

AbstractMonolayer and multilayer ReS2 thin films are obtained by low‐temperature CVD (450 °C, 20 min) of NH4ReO4 and S on a Si/SiO2 (285 nm) wafer using Ar as carrier gas for S.
ChemInform Abstract: Stereoselective Electrophilic Cyclization
Authors: Sakakura Akira , Ishihara Kazuaki 
Published: October 2015

AbstractReview: [rational design of monofunctionalized chiral Lewis base catalysts for enantioselective iodo‐ and protocyclizations as well as nucleophilic phosphite‐urea cooperative catalysts for the stereoselective promotion of electrophilic bromocyclizations; 31 refs.
ChemInform Abstract: Hafnium Trifluoromethanesulfonate [Hf(OTf)4] as a Unique Lewis Acid in Organic Synthesis
Authors: Ishitani Haruro , Suzuki Hirotsugu , Saito Yuki , Yamashita Yasuhiro , Kobayashi Shu 
Published: October 2015

AbstractReview: [62 refs.
ChemInform Abstract: Computational Studies of Synthetically Relevant Homogeneous Organometallic Catalysis Involving Ni, Pd, Ir, and Rh: An Overview of Commonly Employed DFT Methods and Mechanistic Insights
Authors: Sperger Theresa , Sanhueza Italo A. , Kalvet Indrek , Schoenebeck Franziska 
Published: October 2015

AbstractReview: 590 refs.
Heteromerous Bistricyclic Aromatic Enes: Dynamic Stereochemistry of Xanthylidene‐Anthrones
Authors: Suissa M. Rachel , Cohen Shmuel , Pogodin Sergey , Agranat Israel 
Published: October 2015

AbstractThe heteromerous bistricyclic aromatic ene (BAE) 2,2'‐dimethyl‐10‐(9H‐xanthylidene)‐9(10H)‐anthrone (DMXA) was synthesized by a condensation of 10,10‐dichloro‐2‐methylxanthene with 2‐methylanthrone. X‐ray crystallography of (E)‐DMXA and xanthylidene‐anthrone (XA) indicated that the molecules adopt anti‐folded conformations with folding dihedral angles of 44°/44° and 39°/41°, respectively. The crystal structure of anti‐folded (E)‐DMXA does not indicate any xanthenylium–anthracenolate push–pull effect. E,Z‐diastereomerization of DMXA was studied by 1H‐NMR coalescence‐temperature measurements at different magnetic field strengths and by kinetic equilibration experiments. Free energy of activation for this process was 81.5 (±1.3) kJ/mol. B3LYP/6‐311+G(d,p) calculations showed that anti‐folded conformers of XA, (E)‐DMXA, bianthrone (AA), and dixanthylene (XX) were global minima. The twisted conformers of XA, AA, and XX were local minima (ΔG298 = 16, 18, and 24 kJ/mol) with a substantial dipolar xanthenylium–anthracenolate dipolar contribution for XA. Chirality 27:919–928, 2015. © 2015 Wiley Periodicals, Inc.
Lehrstück über Geschichte
Authors: Cornils Boy 
Published: October 2015

AbstractWie schon viele Unternehmen der Chemischen Industrie, zahlreiche Organisationen und selbst das Auswärtige Amt, so hat auch die Gesellschaft Deutscher Chemiker (GDCh) die Geschichte ihrer Vorgängervereine im Dritten Reich als VDCh (Verein Deutscher Chemiker) und DChG (Deutsche Chemische Gesellschaft, beides Gesellschaften, die vorzugsweise Industrie‐ bzw. Hochschulchemiker als Mitglieder umfaßten), Revue passieren lassen und mit dem vorliegenden Buch von H. Maier eine sehr eingehende und bedrückende Schilderung vorgelegt. Auf 741 Seiten (und einem Gewicht von 1,6 kg) wird unter dem Obertiel “Chemiker im Dritten Reich” mit dem Untertitel “Die Deutsche Chemische Gesellschaft und der Verein Deutscher Chemiker im NS‐Herrschaftsapparat” die Herkunft, das Verhalten und das Schicksal der beiden Gesellschaften der deutschen Chemiker geschildert.
Koffein gegen Stress
Authors: Fischer‐Henningsen Doris 
Published: October 2015

AbstractChronischer Stress kann krank machen. Koffein kann über eine Blockade des Adenosinrezeptors A2A Stresssymptome offenbar lindern oder ihnen sogar vorbeugen. Das hat ein internationales Forscherteam unter Federführung der portugiesischen Universität Coimbra kürzlich publiziert [1].
Efficient Light‐Driven Water Oxidation Catalysis by Dinuclear Ruthenium Complexes
Authors: Berardi Serena , Francàs Laia , Neudeck Sven , Maji Somnath , Benet‐Buchholz Jordi , Meyer Franc , Llobet Antoni 
Published: October 2015

AbstractMastering the light‐induced four‐electron oxidation of water to molecular oxygen is a key step towards the achievement of overall water splitting to produce alternative solar fuels. In this work, we report two rugged molecular pyrazolate‐based diruthenium complexes that efficiently catalyze visible‐light‐driven water oxidation. These complexes were fully characterized both in the solid state (by X‐ray diffraction analysis) and in solution (spectroscopically and electrochemically). Benchmark performances for homogeneous oxygen production have been obtained for both catalysts in the presence of a photosensitizer and a sacrificial electron acceptor at pH 7, and a turnover frequency of up to 11.1 s−1 and a turnover number of 5300 were obtained after three successive catalytic runs. Under the same experimental conditions with the same setup, the pyrazolate‐based diruthenium complexes outperform other well‐known water oxidation catalysts owing to both electrochemical and mechanistic aspects.
Comprehensive interactome of Otx2 in the adult mouse neural retina
Authors: Fant Bruno , Samuel Alexander , Audebert Stéphane , Couzon Agnès , El Nagar Salsabiel , Billon Nathalie , Lamonerie Thomas 
Published: October 2015

SummaryThe Otx2 homeodomain transcription factor exerts multiple functions in specific developmental contexts, probably through the regulation of different sets of genes. Protein partners of Otx2 have been shown to modulate its activity. Therefore, the Otx2 interactome may play a key role in selecting a precise target‐gene repertoire, hence determining its function in a specific tissue. To address the nature of Otx2 interactome, we generated a new recombinant Otx2CTAP‐tag mouse line, designed for protein complexes purification. We validated this mouse line by establishing the Otx2 interactome in the adult neural retina. In this tissue, Otx2 is thought to have overlapping function with its paralog Crx. Our analysis revealed that, in contrary to Crx, Otx2 did not develop interactions with proteins that are known to regulate phototransduction genes but showed specific partnership with factors associated with retinal development. The relationship between Otx2 and Crx in the neural retina should therefore be considered as complementarity rather than redundancy. Furthermore, study of the Otx2 interactome revealed strong associations with RNA processing and translation machineries, suggesting unexpected roles for Otx2 in the regulation of selected target genes all along the transcription/translation pathway. The Otx2CTAP‐tag line, therefore, appears suitable for a systematic approach to Otx2 protein–protein interactions. genesis 53:685–694, 2015. © 2015 Wiley Periodicals, Inc.
IL‐2 and IL‐15 regulate CD8+ memory T‐cell differentiation but are dispensable for protective recall responses
Authors: Mathieu Cédric , Beltra Jean‐Christophe , Charpentier Tania , Bourbonnais Sara , Di Santo James P. , Lamarre Alain , Decaluwe Hélène 
Published: October 2015

The ability to mount effective secondary responses is a cardinal feature of memory CD8+ T cells. An understanding of the factors that regulate the generation and recall capacities of memory T cells remains to be ascertained. Several cues indicate that two highly related cytokines, IL‐2 and IL‐15, share redundant functions in this process. To establish their combined roles in memory CD8+ T‐cell development, maintenance, and secondary responses, we compared the outcome of adoptively transferred IL2Rβ+/− or IL2Rβ−/− CD8+ T cells after an acute viral infection in mice. Our results demonstrate that both IL‐2 and IL‐15 signals condition the differentiation of primary and secondary short‐lived effector cells by altering the transcriptional network governing lineage choices. These two cytokines also regulate the homeostasis of the memory T‐cell pool, with effector memory CD8+ T cells being the most sensitive to these two interleukins. Noticeably, the inability to respond to both cytokines limits the proliferation and survival of primary and secondary effectors cells, whereas it does not preclude potent cytotoxic functions and viral control either initially or upon rechallenge. Globally, these results indicate that lack of IL‐2 and IL‐15 signaling modulates the CD8+ T‐cell differentiation program but does not impede adequate effector functions.
Synthesis and Characterization of Chloro‐ and Alkyliron Complexes with N‐Donor Ligands and Their Reactivity towards CO2
Authors: Roth Cristina E. , Dibenedetto Angela , Aresta Michele 
Published: October 2015

AbstractNew iron(II) compounds with N‐donor ligands [2,2′‐bipyridine (bpy) and 2‐(2‐pyridyl)ethylamine (pyea)] were synthesized, and their reactivity with carbon dioxide was investigated. The reactions of Fe(bpy)(pyea)Cl2 (1) with CO2 (0.9 MPa) afforded the carbamato derivative Fe(bpy)(pyea‐CO2)Cl2 (2), which reacted with CH3Li to afford the monomethyl carbamato complex Fe(bpy)(pyea‐CO2)ClCH3 (3), an example of a carbamato species that is stable over a carboxylato moiety. Fe[(bpy)(pyea)](CH3)2 (4), obtained by reaction of 1 with CH3Li, was treated with CO2 (0.3–0.5 MPa) to afford the dicarboxylato species Fe[(bpy)(pyea)](O2CCH3)2 (5), which provides evidence of normal double insertion of CO2 into the Fe–C bond. The reaction of 5 with HCl afforded 1 and CH3–CO2H, which confirmed the mode of bonding of the –O2CCH3 moiety to the Fe center. To verify the preference of insertion of CO2 into the Fe–C or the Fe–N bond, 1 was treated with MeLi (1 equiv.), and Fe(bpy)(pyea)Cl(CH3) (6) was isolated as a low‐melting solid. The latter was treated with CO2 (0.5 MPa), and the product of insertion into the Fe–CH3 bond was observed as the only carboxylate (7). The faster insertion into the Fe–CH3 bond is explained by the fact that the N donor is quaternarized upon interaction with the metal center and has no free electrons available to interact with the C acceptor of the cumulene molecule; thus, more‐forcing conditions (0.9 MPa) are required for the insertion to occur.
Solid‐Supported Iodonium Salts for Fluorinations
Authors: Edwards Richard , de Vries Wilke , Westwell Andrew D. , Daniels Stephen , Wirth Thomas 
Published: October 2015

AbstractSolid‐supported iodonium salt precursors have been prepared and used for the production of fluoroarenes. The importance of the resin functionality for the attachment of the iodonium salt moieties has been demonstrated. Furthermore, the production of new iodonium salt precursors for fluorination has been achieved by an alternative and improved method with respect to those previously described. The successful radiofluorination of a simple solid‐supported precursor with no‐carrier‐added (n.c.a.) [18F]fluoride shows the suitability of the method for the production of useful PET synthons.