bluuebunny/crossref_metadata_2025_split huggingface dataset:
Follicle-stimulating hormone regulates expression and activity of epidermal growth factor receptor in the murine ovarian follicle
Authors: El-Hayek Stephany , Demeestere Isabelle , Clarke Hugh J. 
Published: November 2014

Significance
Ovulation in mammals requires activation of EGF receptor (EGFR) signaling within the ovarian follicle, but the mechanisms responsible for implementing the EGFR network during follicular growth remain incompletely understood. The final phase of growth is driven by FSH. Here we show that during this phase EGFR expression increases sharply in follicular granulosa cells and that this increase requires FSH; we provide evidence that the FSH-dependent increase is essential for EGFR signaling. FSH also is known to induce expression of luteinizing hormone (LH) receptors in the granulosa, permitting them to release EGFR ligands in response to preovulatory LH. By coordinating receptor expression and ligand release, FSH endows fully grown follicles with the capacity to activate EGFR signaling at ovulation.
Targeted carbon conservation at national scales with high-resolution monitoring
Authors: Asner Gregory P. , Knapp David E. , Martin Roberta E. , Tupayachi Raul , Anderson Christopher B. , Mascaro Joseph , Sinca Felipe , Chadwick K. Dana , Higgins Mark , Farfan William , Llactayo William , Silman Miles R. 
Published: November 2014

Significance
Land use is a principal driver of carbon emissions, either directly through land change processes such as deforestation or indirectly via transportation and industries supporting natural resource use. To minimize the effects of land use on the climate system, natural ecosystems are needed to offset gross emissions through carbon sequestration. Managing this critically important service must be achieved tactically if it is to be cost-effective. We have developed a high-resolution carbon mapping approach that can identify biogeographically explicit targets for carbon storage enhancement among all landholders within a country. Applying our approach to Perú reveals carbon threats and protections, as well as major opportunities for using ecosystems to sequester carbon. Our approach is scalable to any tropical forest country.
Oncogenic activity of the regulatory subunit p85β of phosphatidylinositol 3-kinase (PI3K)
Authors: Ito Yoshihiro , Hart Jonathan R. , Ueno Lynn , Vogt Peter K. 
Published: November 2014

Significance
PI3K is a lipid kinase that regulates a broad spectrum of cellular activities. It is a dimeric enzyme consisting of a catalytic and a regulatory subunit. The regulatory subunit stabilizes and inhibits the catalytic subunit. The two major regulatory subunits p85α and p85β have overlapping and unique functions. The data presented here show that in contrast to p85α, the native, wild-type p85β has oncogenic potential and suggest that p85β is a less effective inhibitor of p110 than p85α. These findings are in accord with emerging information that assigns p85β a specific role in human cancer.
The evolution of GRUE
Authors: Grandison Alexandra , Davies Ian R.L. , Sowden Paul T. 
Published: November 2014

The hue spectrum is a continuum of light, yet we perceive it categorically. The categories used to describe this continuum vary across the world’s languages and there are marked differences in the numbers of colour categories and the locations of category boundaries. For example, the green–blue region of colour space is labelled with two terms in English but with only one term (a “grue” term) in many African languages. Evidence for a “grue” term in Otjiherero – a language spoken by the Himba of northern Namibia – has been well documented. Here we present data from colour list and colour naming tasks indicating the emergence of a new Himba colour term. These findings have significant implications for future cross-cultural research into colour categorization.
Color seeing and speaking
Authors: Plebe Alessio , De La Cruz Vivian M. 
Published: November 2014

The ability humans have of seeing colors is strongly influenced by three fundamental factors: biology, which constrains the visual system of our species; the environment, which provides our experience with the world; and language, in which colors acquire names. Recent studies on the Berinmo and Himba languages have challenged the mainstream view about the universalism of color terms. These cases can also be helpful in investigating the possible impact the environment can have, since the landscapes in which the two groups live are drastically different. We propose a computational model of visual and linguistic processing paths in the cortex, previously used for simulating the influence of Berinmo and Himba color terms, and extended for investigating the combined effects of language and environment.
Bach to the blues
Authors: Prado-León Lilia R. , Schloss Karen B. , Palmer Stephen E. 
Published: November 2014

Schloss, Lawler and Palmer (2008) studied the relation between colors and music. We repeated this experiment with forty-nine Mexican participants. The experimental stimuli were thirty-seven colors and eighteen brief samples of classical orchestral music that varied in mode and tempo. Music that was faster and in a major key was associated with brighter, more saturated, warmer colors and was judged to be happier and stronger, whereas music that was slower and in a minor key was associated with darker, less saturated, cooler colors and judged to be sadder, weaker and calmer. We observed high correlations between the emotional associations of music and the emotional associations of the colors, being highest for happy / sad (r = .97) and lowest for angry / calm (r =.68). These results are very similar to the pattern found in North America.
Ovarian embryonal rhabdomyosarcoma is a rare manifestation of the DICER1 syndrome
Authors: de Kock Leanne , Druker Harriet , Weber Evan , Hamel Nancy , Traubici Jeffery , Malkin David , Arseneau Jocelyne , Bouron-Dal Soglio Dorothée , Priest John R. , Foulkes William D. 
Published: November 2014

AbstractEmbryonal rhabdomyosarcoma (ERMS), a malignant soft tissue sarcoma, is one of the most common paediatric cancers. Certain ERMS tumours are associated with the DICER1 syndrome, a distinctive tumour predisposition syndrome caused by germ-line mutations in the microRNA-maturation pathway gene,DICER1. In addition to germ-lineDICER1mutations, highly characteristic somatic mutations have been identified in several DICER1-associated tumour types. These so-called “hotspot” mutations affect highly conserved amino acid residues central to the catalytic activity of the DICER1 ribonuclease IIIb domain.Primary ovarian ERMS (oERMS) is extremely rare. We present a case of a 6-year-old girl with an oERMS found to harbour two mutations inDICER1. In addition to the oERMS, the girl also exhibited other DICER1 phenotypes, including cystic nephroma (CN) and multinodular goitre. Somatic investigations of the CN revealed the presence of a hotspotDICER1mutation different from that in the oERMS. Of particular interest is the CN presented at the age of 12 years, which is much older than previously reported age range of susceptibility (birth to four years of age).This report documents both germ-line and highly characteristic somaticDICER1mutations in a case of oERMS, adding to the expanding spectrum of rare childhood tumours in the DICER1 syndrome.
Automated Update, Revision, and Quality Control of the Maize Genome Annotations Using MAKER-P Improves the B73 RefGen_v3 Gene Models and Identifies New Genes
Authors: Law MeiYee , Childs Kevin L. , Campbell Michael S. , Stein Joshua C. , Olson Andrew J. , Holt Carson , Panchy Nicholas , Lei Jikai , Jiao Dian , Andorf Carson M. , Lawrence Carolyn J. , Ware Doreen , Shiu Shin-Han , Sun Yanni , Jiang Ning , Yandell Mark 
Published: November 2014

Abstract
The large size and relative complexity of many plant genomes make creation, quality control, and dissemination of high-quality gene structure annotations challenging. In response, we have developed MAKER-P, a fast and easy-to-use genome annotation engine for plants. Here, we report the use of MAKER-P to update and revise the maize (Zea mays) B73 RefGen_v3 annotation build (5b+) in less than 3 h using the iPlant Cyberinfrastructure. MAKER-P identified and annotated 4,466 additional, well-supported protein-coding genes not present in the 5b+ annotation build, added additional untranslated regions to 1,393 5b+ gene models, identified 2,647 5b+ gene models that lack any supporting evidence (despite the use of large and diverse evidence data sets), identified 104,215 pseudogene fragments, and created an additional 2,522 noncoding gene annotations. We also describe a method for de novo training of MAKER-P for the annotation of newly sequenced grass genomes. Collectively, these results lead to the 6a maize genome annotation and demonstrate the utility of MAKER-P for rapid annotation, management, and quality control of grasses and other difficult-to-annotate plant genomes.
Polyaniline based red oxide primer paint for efficient corrosion protection
Authors: Rajasekharan V. , Manisankar P. 
Published: November 2014

Purpose
– The purpose of this study is to introduce mechanochemically prepared polyaniline anticorrosive additives. In primer coating technology, there is an increasing interest in the development of efficient anticorrosive additives which replace the conventional inorganic anticorrosive pigments like heavy metal chromates and phosphates normally added to primer paints for the coating on metals. Conducting polymers are found to be better alternatives.

Design/methodology/approach
– Polyaniline phosphate is synthesized through solid-state conditions without using any solvent. The synthesized polyaniline phosphate is added in the primer formulation instead of zinc phosphate. Primers with different quantity of zinc phosphate are also formulated and studied for comparison. The comparison between their abilities to control corrosion of carbon steel were done with application of open-circuit potential monitoring, polarization and electrochemical impedance spectroscopy methods in 3.5 per cent NaCl solution.

Findings
– Corrosion studies indicate that polyaniline phosphate can improve corrosion protection properties by taking part the passivation processes. The performance of polyaniline phosphate is better than zinc phosphate.

Originality/value
– I certify that the results are from our original research and this paper is neither considered for publication elsewhere nor published previously.
Corrosion of welded joints of bimetallic composite tube in simulated offshore gas field environment
Authors: Hongda Deng , Shunpeng Zeng 
Published: November 2014

Purpose
– The purpose of this investigation was to research the corrosion behavior of welded joints of bimetallic composite tube (X65/316L) welded with Inconel 625 in simulated sea water and in simulated production water, respectively.

Design/methodology/approach
– The different electrochemical corrosion and galvanic corrosion behaviors of different welded zones were identified using the dynamic potential scan method and galvanic corrosion technique.

Findings
– The heat-affected zone (HAZ) of welded joints was the most critical zone for corrosion. The closer to the welding line, more severe was the corrosion that was evident in the HAZ at room temperature. In welded joints of X65 tested in simulated seawater, tremendous corrosion occurred in the HAZ, followed by the base metal, and finally the welding line. However, there were few differences in corrosion of the different zones of welded joints in 316L in simulated production water. In such joints of 316L, corrosion comparatively attacked more easily to the HAZ. In galvanic corrosion tests, tremendous galvanic corrosion was evident on welded joints on X65, but comparatively slight gavanic corrosion appeared at welded joints in 316L. With the increased temperature, galvanic corrosion of welded joints was enhanced.

Originality/value
– The results can provide reference for reducing the gavalic corrosion of welded bimetallic composite tube metal in the actual operation.
Identification and assessment risks in maintenance operations
Authors: Wijeratne W.M.P.U. , Perera B.A.K.S. , De Silva L. 
Published: November 2014

Purpose
– The purpose of this paper is to identify the risks and methods for their assessment in the case of maintenance activities in Sri Lanka. The main objectives were to identify the occupational risks in maintenance work and the risk assessment methods in place and their drawbacks in the Sri Lankan context.

Design/methodology/approach
– The identification and assessment of risks were undertaken through a study of three fast-moving consumer products manufacturing organisations. The relevant data were collected through personal interviews and site visits.

Findings
– Most typical risks associated with maintenance are cuts, slips and falls, with severe or fatal injuries as the result of negligence of SOP and failure to use the PPE. Checklists, brainstorming and decomposition techniques were identified as the preferred methods in maintenance for risk identification while a risk rating matrix is used for risk analysis. Lack of awareness and indifference towards risk assessment; make effective risk assessment very difficult. These drawbacks can be minimised by education, systematic training and enforcing rules, regulations and procedures for controlling risks.

Originality/value
– Studies on maintenance worldwide have identified several maintenance-specific risks such as working at heights, the pressure of time, etc. However, there is a dearth of published research on risks and risk assessment methods in maintenance in Sri Lankan context. The findings highlighted the safety risks and risk assessment tools entailed in the maintenance operations of manufacturing organisations. The findings will be useful for those in maintenance operations in managing risks effectively through designing work environments that are risk-free.
Improving investment sustainability for PPP power projects in emerging economies
Authors: Atmo Gigih , Duffield Colin 
Published: November 2014

Purpose– Many electricity projects in Asian emerging economies involve private finance using Public Private Partnerships (PPPs) yet problems remain in terms of project initiation, commercial structuring, and financial arrangements. The motivation to pursue previous PPP power projects has been unduly influenced by the ability to attract finance rather than an independent assessment of value for money (VfM) of the project. The purpose of this paper is to present the development of VfM framework for improving investment sustainability of PPP power projects in Asian emerging economies.Design/methodology/approach– The drivers for achieving VfM in projects involving both public and private participants have been determined by a critical review of international practices and the development of sustainable energy systems using grounded theory. These drivers have been used to cross-analyse six Asian PPP power projects.Findings– The evaluation of the case study projects identifies the key determining linkages between the project structure, financial and commercial arrangements, and technical solutions with the ultimate project outcomes. It has been established that project outcomes can be improved through the inclusion of VfM considerations, energy security, and environmental sustainability. On the basis of this investigation, a conceptual governmental decision framework for future investment in PPP power projects is proposed.Originality/value– Advocating a VfM framework for assessment of PPP power project proposals in Asian emerging economies is a new approach and offers enhanced benefits both to the public and private sector.
System development toward effective maintenance management practices
Authors: Ismail Zul-Atfi 
Published: November 2014

Purpose
– The current maintenance management method has affected the efficiency of the building facility management at Polytechnics. Many issues such as poor service delivery, inadequate finance, poor maintenance planning and maintenance backlogs have emerged due to the usage of conventional method application (paper-based form and unsystematic database). Therefore, the proposed system improvement is intended to be used for maintenance management practices at Malaysian Polytechnics in order to provide high quality of building facility with safe and healthy environments. The paper aims to discuss these issues.

Design/methodology/approach
– Eight Polytechnics were selected based on major problems of using conventional method in the comparison to investigate the maintenance management practices in each Polytechnic.

Findings
– The overall findings of this research indicated; poor service delivery, inadequate financial, poor maintenance planning and maintenance backlogs. The system architecture and the conceptual process model are presented to integrate the information database and maintenance management processes in improving the building diagnosis approach and decision-making process for managing building maintenance.

Originality/value
– This new system development provides a better maintenance assessment for identifying symptoms, causes and reasons of building defects without depending on the expensive instruments, for instance, non-destructive testing (NDT) and sensor technology. It also has the potential to become the successful technology in assisting the maintenance contractors, clients and developer for effective management of maintenance defects at Polytechnic.
The state of corporate citizenship in Brazil
Authors: Amaral Lauriano Lucas , Spitzeck Heiko , Henrique Dutra Bueno João 
Published: November 2014

Purpose– This paper aims to present the state of corporate citizenship in Brazil.Design/methodology/approach– The results of a survey of Brazilian companies is used to analyze the state of corporate citizenship in Brazil. The survey was constructed using the methodology developed by Mirvis & Googins on measuring the stage of corporate citizenship, and 172 valid responses from Brazilian companies were received.Findings– Data suggest that Brazilian companies have an advanced understanding of corporate citizenship and the strategic intention to integrate citizenship into their business. When it comes to leadership, structures, issue management, stakeholder relationships and transparency, however, their maturity in terms of citizenship stays in less advanced stages. In sum, Brazilian companies are advanced in the concept but less developed in the practice of corporate citizenship.Research limitations/implications– The sample consists of 172 valid responses from companies in Brazil acting in various sectors and thus does not allow the determination of citizenship maturity in selected sectors.Practical implications– The research points to a gap regarding understanding and practice in corporate citizenship in Brazil. To foster evolution of corporate citizenship, Brazilian companies are advised to work especially on leadership engagement, organizational structures, issue management, stakeholder relationships and transparency.Originality/value– This is the first study about the maturity of corporate citizenship in Brazilian companies.
Governance and microfinance institutions
Authors: Bakker Anuschka , Schaveling Jaap , Nijhof André 
Published: November 2014

Purpose
– This paper aims to determine the influence of governance mechanisms on sustainability and outreach of microfinance institutions (MFIs). Corporate governance has been identified as a key bottleneck in strengthening MFIs’ sustainability (financial performance) and increasing their outreach (social impact).

Design/methodology/approach
– First, a literature study to give insight in the microfinance sector is provided. Subsequently, the data research has been performed based on the statistics of one of the funds of a Dutch independent investment manager, which is focused on responsible investments in developing countries. Hierarchical multiple regression analyses were conducted to examine the association between governance mechanisms and the respective dependent variables.

Findings
– The results show that boards of a MFI with insiders (for example, employees) are a significant predictor of sustainability. Regulation impacts sustainability significantly in a negative way. Overall, the study shows that only a limited number of variables influence the sustainability and outreach of an MFI.

Research limitations/implications
– The limitation of the studied investment fund is that it invests in expanding and mature MFI’s. So the results of this research can only be generalized to expanding and mature MFI’s.

Practical implications
– The governance mechanisms that are recommended in the industry guidelines and which are studied here are often not relevant in respect to sustainability and outreach of MFIs. The approach to microfinance governance should be broadened by focusing more on stakeholders and the decision making process in an MFI.

Social implications
– Good governance is key for the microfinance institutions and even more complicated than for regular companies that do not have a double bottom line (sustainability and outreach). to be successful in the future, and for clients to reach the best end result, it is essential that the governance mechanisms that influence the bottom line are determined.

Originality/value
– Not much research has been done with respect to the governance mechanisms, which have impact on the sustainability and outreach of MFIs.
What makes a “good manager”? Positioning gender and management in students’ narratives
Authors: Gherardi Silvia , Murgia Annalisa 
Published: November 2014

Purpose
– The purpose of this paper is to address the relationships between gender and management in the narratives of students. More specifically, the authors discuss how the discourse on management is mobilized as a discursive practice able to make some form of that activity thinkable and practicable: who can be a CEO? What kind of managerial competencies are attributed to men/women CEOs? What kind of moral order is expressed in the stories told?

Design/methodology/approach
– Stimulus texts have been used to elicit narratives. Students were asked to complete a short story regarding a fictive managerial character, either female or male, whose performance and attitude they were asked to evaluate.

Findings
– The paper discusses how the collected stories as a whole expressed a conception of what counts as a “good manager” and how management is gendered. In the analysis, the authors discuss whether and how the relationships between gender and management are changing, or the basic assumptions about “think manager-think male” are still valid. The paper illustrates a traditional positioning of gendered management along the lines of rationality vs care, and a third positioning in which the ideal of the “good manager” has both competencies.

Originality/value
– The authors designed an alternative research strategy focused on how gender and management are discursively constructed within a context of economic crisis that affects management reputation. Particularly, the authors discuss the surprising results concerning how the written stories evaluating male CEOs distrusted the masculine way of managing and positioned the female managing style within a trustworthy context.