bluuebunny/crossref_metadata_2025_split huggingface dataset:
Factores de Riesgo que Determinan el Sobrepeso y la Obesidad en Niños de 5 a 9 Años de Edad Atendidos en la Unidad de Medicina Familiar de San Juan Bautista Tuxtepec, Oaxaca
Authors: Gomez Rosales Claudia , García Arano Víctor , Cruz Sacramento Ángela Carlota , Luis Avendaño Maribel 
Published: August 2024

Introducción: El sobrepeso y la obesidad infantil se han convertido en una pandemia silenciosa y un problema de salud pública importante, considerada una enfermedad crónica caracterizada por exceso de grasa en el organismo, presente cuando el niño tiene un sobrepeso mayor al 20% de peso ideal de relevancia a nivel mundial, los efectos son devastadores, las víctimas son inocentes, resultado de la mercadotecnia de una sociedad industrializada e indolente, que resulta un desafío en la salud pública actual. Es por ello el personal de salud juega un papel fundamental en la prevención, detección y control de esta, identificando cuáles son los factores de riesgo que determinan el sobrepeso y la obesidad. Objetivo general: Determinar cuáles son los factores de riesgo para el desarrollo del sobrepeso-obesidad en niños de 5 a 9 años de edad. Material y Métodos: Diseño transversal, descriptivo, observacional, analítico, Universo de trabajo niños menores de 5 a 9 años de edad. Para análisis estadístico se realizó medidas de tendencia central y de dispersión, así como correlación de Chi-cuadrado de Pearson para variables cuantitativas. Experiencia de grupo: La Dra. Ángela Carlota Cruz Sacramento, Especialista y Maestría en Salud ICEST, Maestría en administración de Hospitales ICEST, Dra. Maribel Luis Avendaño médico especialista en Medicina Familiar. Dr. Víctor García Arano con especialidad en Pediatría avalada por el Hospital Infantil privado por la Universidad Nacional Autónoma de México, Maestría en Salud Pública. Resultados: Se estudió a 171 niños con rango de edad mínima de 5.6 años y edad máxima de 9.7 años. De acuerdo con la hipótesis de trabajo, se concluyó que más de la mitad presenta sobrepeso de los niños encuestados derechohabientes de la Unidad de Medicina Familiar de San Juan Bautista Tuxtepec, condicionando a que en un futuro puedan desarrollar enfermedades crónicas. Según el resultado del índice de masa corporal, se demostró un mayor incremento de sobrepeso con 123 niños (71.9%), y con una proporción menor la obesidad en 48 niñas (28.1%). Conclusiones: Se pudo comprobar que el Factor Nutricional y Social están mayormente relacionados con el sobrepeso y obesidad en niños de 5 a 9 años de edad atendidos en la Unidad de Medicina Familiar de San Juan Bautista Tuxtepec, Oaxaca.
Tantangan Penggembalaan Terhadap Jemaat dari Kaum Marginal di Tengah Kota
Authors: Andreson Situmorang Benny , Br Sembiring Dina 
Published: August 2024

Kehidupan di kota identik dengan gaya hidup yang serba cepat dan modern, perubahan terjadi begitu cepat mengikuti perkembangan zaman. Sehingga gereja – gereja di kota juga harus mampu mengikuti perubahan itu tanpa harus kehilangan nilai – nilai kebenaran. Dengan demikian hamba Tuhan atau para gembala diperhadapkan dengan berbagai macam tantangan dalam pelayanan. Sebab masyarakat di kota sangat beragam, mulai dari suku, pekerjaan, pendidikan, status sosial dan ekonomi. Perbedaan status ekonomi mulai dari kaum marjinal sampai yang sangat kaya. Pada kenyataannya gereja – gereja juga mengalami kesulitan untuk menjangkau dan melayani jemaat yang berasal dari kaum marginal. Namun Hamba Tuhan diharapkan mampu memenuhi kebutuhan jemaat yang serba komleks. Hamba Tuhan diharapkan dapat memenuhi kebutuhan jemaat yang sangat kompleks. Hamba Tuhan bukan hanya dituntut untuk dapat memenuhi kebutuhan spiritual jemaatnya, namun juga dituntut untuk dapat memenuhi kebutuhan-kebutuhan yang lain dari jemaatnya. Gembala dituntut menjadi orang yang serba bisa dalam pelayanan yang diembannya. Hamba Tuhan dituntut untuk dapat menjalankan semua tugas pelayanan penggembalaan dengan maksimal. Apabila hamba Tuhan dianggap gagal dan lalai untuk menjalankan kewajibannya dengan maksimal maka akan menghadapi berbagai macam konsekuensi, bahkan ditinggalkan oleh jemaat. Segala tantangan dalam pelayanan seharusnya tidak membuat hamba Tuhan kecewa dan tawar hati apalagi mengambil keputusan untuk mundur dan meninggalkan pelayanan. Oleh karena itu, hamba Tuhan harus mempersiapkan diri dengan baik dalam menghadapi tantangan penggembalaan yang kompleks.
Morphological and semantic priming in word recognition
Authors: Askari Afsane , Mahdi-Kamo Sallar 
Published: August 2024

Word recognition is investigated along with semantic priming. While semantic priming has received attention among scholars investigating language processing in the last five decades, the literature lacks an investigation of semantic priming in word recognition among native and non-native German-speakers. To investigate the differences in how native speakers (L1) and non-native speakers (L2) of recognize words, and their corresponding speed, we designed two experiments consisting of two conditions; when the primes are associated with the target word, and when the primes are not related to the target word. For the semantic category, identical conditions were designed; when the primes are associated with the target word, and when they are not related to the target word. Reaction Time (RT) and accuracy were obtained during the experiments on both groups (L1 and L2). The experiment was controlled by the DMDX software package. The results indicate that there are no such differences among native speakers(L1) and non-native speakers of the German language unless in individual choices. There are similarities among first language speakers (L1) and second language speakers (L2) in both categoriesــــmorphology and semantics. The delay would occur when non-native speakers see a word in morphological and semantic priming.
The sharp bound of the third Hankel determinant for certain subfamilies of analytic functions
Authors: Rath Biswajit , Kumar K. Sanjay , Krishna D. Vamshee , Viswanadh G. K. Surya 
Published: August 2024

UDC 517.5
We study an upper bound and the sharp bound of the third-order Hankel determinant for some subfamilies of analytic functions for the parameters

α
∈

(
1,4
/
3
]

and

α
=
3
/
2
,

respectively, also proving the recent conjecture for the sharp bounds made in [Virendra Kumar, Sushil Kumar, V. Ravichandran, <em>Third Hankel determinant for certain classes of analytic functions</em>, Mathematical Analysis I: Approximation Theory, February (2020); DOI: 10.1007/978-981-15-1153-019].
Cell-surface Milieu Remodeling in Human Dendritic Cell Activation
Authors: Udeshi Namrata D , Xu Charles , Jiang Zuzhi , Gao Shihong Max , Yin Qian , Luo Wei , Carr Steven A , Davis Mark M , Li Jiefu 
Published: August 2024

Abstract
Dendritic cells (DCs) are specialized sentinel and APCs coordinating innate and adaptive immunity. Through proteins on their cell surface, DCs sense changes in the environment, internalize pathogens, present processed Ags, and communicate with other immune cells. By combining chemical labeling and quantitative mass spectrometry, we systematically profiled and compared the cell-surface proteomes of human primary conventional DCs (cDCs) in their resting and activated states. TLR activation by a lipopeptide globally reshaped the cell-surface proteome of cDCs, with &gt;100 proteins upregulated or downregulated. By simultaneously elevating positive regulators and reducing inhibitory signals across multiple protein families, the remodeling creates a cell-surface milieu promoting immune responses. Still, cDCs maintain the stimulatory-to-inhibitory balance by leveraging a distinct set of inhibitory molecules. This analysis thus uncovers the molecular complexity and plasticity of the cDC cell surface and provides a roadmap for understanding cDC activation and signaling.
Cutting Edge: Retinoic Acid Promotes Brain-homing of CD8+ T Cells during Congenital Cytomegalovirus Infection
Authors: Hilt Zachary T , Charles Wisler , Ali Taha , Smith Casey V , Zhang Shide , Wesnak Samantha P , Smith Norah L , Rudd Brian D 
Published: August 2024

Abstract
The most common congenital viral infection is CMV, which leads to numerous neurologic disabilities. Using a mouse model of congenital CMV, we previously determined that Ag-specific CD8+ T cells traffic to the brain in a CCR9-dependent manner. The mechanism by which these CD8+ T cells acquire a CCR9-dependent “brain-tropic” phenotype remains unclear. In this study, we identify the key factor that imprints brain homing specificity on CD8+ T cells, the source of production, and the location where CCR9 expression is induced. Specifically, we discovered that CCR9 is induced on CD8+ T cells by retinoic acid–producing CD8α+ dendritic cells in the cervical lymph node postinfection. We found that retinoic acid is important for CD8+ T cells to establish tissue residency in the brain. Collectively, our data expand the role of retinoic acid during infection and mechanistically demonstrate how CD8+ T cells are primed to protect the brain during congenital viral infection.
Insulin-induced Lipohypertrophy in a Patient with Type 2 Diabetes
Authors: Chauhan Vikram S. , Joseph Ashitha G. 
Published: August 2024

Abstract
Lipohypertrophy (LH) is a common side effect of insulin treatment in patients with diabetes, characterized by soft, benign nodules in the subcutaneous tissue. This case report describes the management of insulin-induced LH in a 66-year-old male with type 2 diabetes. The patient had been on a combination of oral antidiabetic agents (ODAs) and biphasic human insulin for 5 years, experiencing the symptoms of numbness, leg swelling, fatigue, and frequent hypoglycemic episodes. Upon examination, LH with skin pigmentation was observed at the insulin injection sites on both calves. The patient’s laboratory investigations revealed poor glycemic control with high glycated hemoglobin percentage. To address the condition, the patient was advised to change the injection site, use proper site rotation, and change the insulin needle daily. The insulin therapy was modified by switching to biphasic premixed analog insulin injected 5 min before meals using the insulin pen. In addition, ODAs were adjusted for better glycemic control. Following these interventions, the patient reported improved glucose levels and stable kidney function. This case report emphasizes the importance of early detection and appropriate management of insulin-induced LH through patient education and insulin therapy adjustments. Health-care providers should remain vigilant for LH and educate patients on proper injection practices to optimize diabetes management and prevent complications.
Type 3 Diabetes Mellitus, Insulin Resistance, Alzheimer’s Disease and Role of Alpha-Linolenic Acid in Blood–Brain Barrier Repair
Authors: Zanwar Anand A. , Joshi Asavari A. , Gaikwad Prajakta S. , Hegde Mahabaleshwar V. 
Published: August 2024

Abstract
Alzheimer’s disease (AD), is often referred to as Type 3 diabetes mellitus (T3 DM). It has now become evident that T3 DM contributes significantly to the pathogenesis of AD. The T3 DM has a distinct identity being very much selective for blood–brain barrier (BBB) and separated from peripheral diabetes. Alpha-linolenic acid (18:3, ALA) is considered an essential fatty acid that is responsible for the formation of long-chain eicosapentaenoic acid (20:5) and docosahexaenoic acid (22:6, DHA). DHA is an important structural fatty acid of the human brain. The recent literature comes to the conclusion that ALA is an ideal source of DHA. T3 DM can cause, insulin resistance in the brain and impairment in glucose utilization. This has very serious implications on BBB integrity. It has been shown now that ALA very efficiently can provide energy to endothelial cells of the BBB by β-oxidation and facilitate DHA entry to the brain. It has also been shown that some DHA is formed in BBB and some ALA that enters the brain also gets converted to DHA. The role of other players such as Apolipoprotein E protein, Tau and Beta-amyloid, and glycogen synthase kinase are briefly mentioned. The new findings, that the primary event in BBB damage is the pathogenesis of AD, may help in the development of new more effective drugs and treatment modalities.
Managing Foreign-body Injuries in Individuals with Diabetes: A Diagnostic Challenge
Authors: Kavitha Karakkattu V , Unnikrishnan Ambika G. 
Published: August 2024

Abstract

Introduction:
Diabetes often leads to diabetic foot infections, resulting in hospitalizations and amputations. Foreign-body (FB) injuries in diabetes present significant diagnostic challenges. This study aims to unravel the complexities of FB injuries, focusing on implications, diagnostic hurdles, and management strategies due to their association with delayed detection and complications.

Methods:
A retrospective analysis was performed on 28 patients who visited the Chellaram Diabetes Institute, Pune, between June 2014 and August 2021, with a history of FB injury. We collected their clinical, radiological, microbiological and biomedical data including clinical outcomes.

Results:
The study included 28 subjects (71.43% males, 28.57% females) with a mean age and duration of diabetes of 65.07 ± 7.26 and 17.89 ± 9.15 years respectively. Peripheral neuropathy was observed in 95.83% of subjects. Imaging was used in 21 subjects: X-ray (n = 21; 5 had FBs) and ultrasound (n = 13; 6 had FBs). FBs were retrieved in 18 cases, with imaging detecting them in 9 cases (X-ray only: 3, X-ray + USG: 2, USG only: 4). In 12 subjects, FBs were removed bedside as accidental findings. The most common FB was a stone (n = 9), followed by wooden splinters (n = 6) and thorns (n = 6). Removal procedures were performed on both hospitalized and nonhospitalized subjects, highlighting undiagnosed injuries.

Conclusion:
This study underscores the importance of radiological modalities in detecting FBs and assessing the extent of infection they cause, aiming to enhance future FB management.
Comparison of the neuraxial acoustic window in hamstring stretch position and cross-legged position: An observational pilot study
Authors: Sethi Priyanka , Kaur Manbir , Balakrishnan N. , Singh Govind , Dang Deepanshu , Kumari Kamlesh , Bhatia Pradeep Kumar 
Published: August 2024

Background:
The patient’s position determines the success of the block during neuraxial anesthesia. We compare the neuraxial acoustic window in two positions namely, the hamstring stretch position (HSP) and the crossed-leg position, which are the modifications of sitting positions during spinal and epidural anesthesia.

Methodology:
This observational pilot study was conducted from October 2021 to November 2021 after approval from the ethics committee of our institution. Patients belonging to the age group 18–45 years were included. Forty patients were enrolled and each patient was asked to position him or herself in these two different sitting positions.

Results:
There was no statistically significant difference in the interlaminar distance (ILD) (P = 0.25), depth of ligamentum flavum (LF) from the skin, and intrathecal distance (P = 0.444) in these two sitting positions. The patients were more comfortable in the cross-leg position (P = 0.021).

Conclusion:
Both the positions, cross-leg position and HSP have no difference in ILD and depth of LF from the skin but patients were comfortable in cross-leg position.
Pendampingan Sistem Informasi Desa Berbasis Internet di Desa Laikaaha Kecamatan Ranomeeto Konawe Selatan
Authors: Lestari Lina , Variani Viska Inda , Rusman La Ode , Raharjo Sapto , Midana Ashari 
Published: August 2024

Laikaaha Village, Ranomeeto District, is one of the villages in South Konawe, Southeast Sulawesi which has diversity in social life. This diversity consists of economic capacity, education, resilience and health which provides its own challenges for the Village Government to develop village development programs. Determining village policies or preparing village programs is very dependent on accurate data, so managing village data and information is very important. Apart from that, the use of an internet-based information system is one of the facilities that can help the Village Government in implementing village programs. Currently, data traffic always moves fast, so assistance is provided with the management of internet-based information systems to produce reliable human resources to manage it. The output of this activity is to increase the capacity of village information system managers so that information system utilization can be maximized. In this activity, the community as users is also involved, and assistance has been provided on how to utilize the existence of the information system. The aim of this community service activity plan is that the Laikaaha Village community has knowledge about the use of information systems, information system managers can improve their skills, the Village Government can make policies and develop programs that are more precise and faster.
Pelatihan Pembuatan Sabun Ramah Lingkungan Dari Buah Lerak Sebagai Implementasi Model Pemberdayaan Ibu Rumah Tangga
Authors: Rejeki Desi , Nur Halimah  , Dewi Puspa Arisandi  , Moh Syahrul Munir  
Published: August 2024

Limbah detergen merupakan persoalan lingkungan harus diprioritaskan. Limbah detergen memiliki dampak besar dalam mencemari lingkungan dan merusak ekosistem. Di limbah detergen terkandung surfaktan yang dapat mencemari air dan biota yang ada. Limbah busa yang dihasilkan deterjen disinyalir mengakibatkan mikroorganisme didalam air kekurangan asupan oksigen. Selain itu kemasan pada detergen rata-rata berbahan plastik sehingga menyumbang pencemaran lingkungan. Ibu rumah tangga merupakan bagian dari masyarakat yang menghasilkan limbah deterjen setiap harinya. Sehingga peran ibu rumah tangga menjadi sangat penting untuk meminimalisir pencemaran limbah deterjen kimia. Pengabdian ini dinyatakan berhasil ditinjau dari aspek afektif dan kognitif, peserta pelatihan telah memahami cara membuat sabun alami dari buah lerak dan memahami bahaya pencemaran limbah deterjen kimia. Oleh karena itu untuk mengetahui tingkat keberhasilan kegiatan ini maka metode yang digunakan adalah dengan memberikan kuesioner yang dibagikan sebelum dan setelah pemaparan materi yang berisi pertanyaan-pertanyaan yang berkaitan dengan materi pelatihan. Berdasarkan hasil kegiatan pengabdian yang telah dilakukan disimpulkan bahwa pemaparan materi yang disampaikan , diterima dengan baik dan mampu menarik minat peserta untuk terlibat aktif dalam diskusi. Sehingga didapatkan peningkatan pengetahuan peserta tentang pelatihan pembuatan sabun ramah lingkungan dari buah lerak untuk mendukung peningkatan kualitas lingkungan yang diketahui dari perbandingan hasil kuesioner sebelum dan setelah penerimaan materi.
Wisata Syariah dan Strategi Pengembangannya di Era Digital Pada Beberapa Tempat Wisata di Sumatera Barat
Authors: Ezizwita Ezizwita , Srihasnita Rita , Maivalinda Maivalinda , Firsta Firsta , Oktovia Nettry , Agustin Fenny 
Published: August 2024

Tourism is one of the government's main sectors to increase revenue. In 2016, West Sumatra was designated as a Global Halal Tourism Destination in Abu Dhabi, which is expected to provide an impetus for West Sumatra's government to introduce Sharia tourism in their area. The concept of Sharia tourism is to apply Islamic values to all aspects of tourism activities. This is very suitable to be implemented in West Sumatra Province where the majority of the population is Muslim. This research aims to identify the appropriate development strategies that can be applied by adopting the concept of Shariah tourism and using digital marketing for several tourist attractions in West Sumatra. By using a SWOT analysis, the opportunities and challenges faced by the Sharia tourism sector can be identified. As a result, a strategy can be practically applied by the Sharia tourism business in facing the digital era. This research is expected to raise awareness about the importance of digitalization skills in product marketing. The research method is descriptive qualitative. Through the SWOT analysis, it is possible to identify the various SWOTs and to formulate the digital marketing based strategy for the development of Islamic tourism in West Sumatra

Abstrak
Sektor pariwisata merupakan salah satu sektor andalan bagi pemerintah untuk menambah pendapatan. Ditetapkannya Sumatera Barat sebagai daerah tujuan pariwisata halal dunia dalamWorld Halal Tourism di Abu Dhabi tahun 2016, selayaknya dijadikan momentum oleh Pemerintah Provinsi Sumatera Barat untuk menerapkan pariwisata berbasis syariah di wilayahnya. Konsep wisata syariah adalah menerapkan nilai-nilai ke Islaman ke dalam seluruh aspek kegiatan wisata. Hal ini sangat sesuai untuk diterapkan di Provinsi Sumatera Barat yang penduduknya mayoritas beragama Islam. Penelitian in bertujuan untuk melihat strategi pengembangan apa yang cocok diterapkan yang mengusung konsep wisata syariah dengan memanfaatkan Digital Marketing pada beberapa objek wisata yang ada di Sumatera Barat. Melalui SWOT dapat diketahui peluang dan tantangan yang dihadapi oleh dunia wisata syariah sehingga diperoleh suatu strategi yang bisa diterapkan oleh bisnis wisata syariah. Penelitian ini diharapkan dapat meningkatkan kesadaran akan pentingnya kemampuan digitalisasi dalam pemasaran produk. Metode penelitian yang digunakan adalah kualitatif deskriptif. Dengan analisa SWOT, dapat diketahui berbagai kekuatan, kelemahan, peluang dan ancaman yang dimiliki dan dihadapi oleh wisata syariah di Sumatera Barat, sehingga akan diperoleh suatu strategi pengembangan wisata syariah berbasis Digital Marketing yang bisa diterapkan di Sumatera Barat.
MISSÕES DE MANUTENÇÃO DA PAZ E OS SEUS REFLEXOS SOCIOECONÔMICOS
Authors: Do Couto Pereira Raphael , Mello de Lima Fernanda , Aguilera Negrete Ana Carolina 
Published: August 2024

Este trabalho tem como objetivo apresentar as ações da Missão das Nações Unidas para a Estabilização do Haiti e seus reflexos na economia daquele país. Serão descritas as operações de paz, o histórico e evolução político econômica do Haiti, os reflexos das crises políticas na economia haitiana, a crise haitiana e intervenção das Nações Unidas, ainstauração da Missão das Nações Unidas para Estabilização do Haiti (MINUSTAH), o Governo Transitório, o Interim Cooperation Framework (ICF), a MINUSTAH e estruturação sócio-político e econômica do Haiti, o furacão Jeanne e o apoio da MINUSTAH e da ICF ao país, a economia haitiana pós-crise, a evolução econômica do Haiti e o terremoto e suas conseqüências econômicas. Essa descrição tem como fontes os documentos gerados pela Comissão Econômica Para a América Latina e o Caribe (CEPAL). São eles: Haiti: Évolution Économique De L’année 1999; Haití: Evolución Económica Durante 2004 y Perspectivas para 2005; Haití: Evolución Económica Durante 2005 y Perspectivas para 2006; Haití: Evolución Económica Durante 2007 y Perspectivas para 2008 e Haití Evolución Económica durante 2010, utilizados na demonstração da evolução econômica haitiana, a fim de aferir os impactos causados na economia do país até o pós terremoto em 2010. A metodologia empregada será documental e bibliográfica: documental porque serão utilizados textos legais, atos normativos de âmbito Internacional e bibliográfica, pois que serão pesquisados doutrinas e textos acadêmicos de assuntos relacionados ao tema.