bluuebunny/crossref_metadata_2025_split huggingface dataset:
Facing the COVID‐19 pandemic: An Italian feasibility study of a mixed in‐person/telerehabilitation intervention for cancer patients
Authors: Denti Monica , Pecorari Alessia , Accogli Monia A. , Costi Stefania , Mainini Carlotta , Pellegrini Martina , Boni Chiara , Barbara Bressi , Braglia Luca , Fugazzaro Stefania 
Published: August 2024

AbstractIntroductionThe COVID‐19 pandemic impacted healthcare organizations, necessitating a rapid transition from in‐person to virtual care.Our study explored the feasibility of a mixed in‐person/telerehabilitation intervention for cancer patients and its effects on cancer‐related fatigue (CRF), quality of life (QoL), physical function, patient satisfaction, and perceived usefulness.MethodsTRACE 2020 is an observational prospective study that enrolled adult cancer patients, between January 2021 and March 2023, who were eligible for a rehabilitation program to be provided also in telerehabilitation.Patients were assessed at baseline and after the rehabilitation program. Adherence to sessions, reasons for non‐adherence and adverse events were collected.ResultsOf the 23 patients enrolled, 87% received a mixed intervention, with an average of 60% in‐person sessions and 40% telerehabilitation sessions. Adherence was very high (91%). Evaluation scales showed an improvement in CRF, QoL, and lower limb strength and a relevant increase in patients' level of physical activity (PA). Most patients reported good satisfaction; the few criticisms mainly concerned difficulties in connectivity, lack of physical contact and difficulties in understanding how to perform exercises during telerehabilitation sessions. The physiotherapist underlined the usefulness of the innovative approach and suggested ways to facilitate future implementation.ConclusionA mixed intervention including telerehabilitation is feasible and accepted by cancer patients. It may have a positive effect on their CRF, QoL, and level of PA and render patient care more flexible. The findings suggest what characteristics the target population for telerehabilitation should have, in order to integrate telerehabilitation in standard care for cancer patients.
Successful management of carinal shift in aortic dissection: A case report of innovative airway management strategies
Authors: Chaudhary Rahul Kumar , Khan Sajjad Ahmed 
Published: August 2024

Key Clinical MessageThe case underscores the necessity of adaptable airway management strategies in aortic dissection surgeries complicated by carinal shift. Successful lung isolation was achieved using a single‐lumen endotracheal tube after failed attempts with traditional methods and bronchial blockers.
CD99 contributes to the EWS::FLI1 transcriptome by specifically affecting FOXM1‐targets involved in the G2/M cell cycle phase, thus influencing the Ewing sarcoma genetic landscape
Authors: Pasello Michela , Laginestra Maria Antonella , Manara Maria Cristina , Landuzzi Lorena , Ruzzi Francesca , Maioli Margherita , Pellegrini Evelin , De Feo Alessandra , Lollini Pier‐Luigi , Scotlandi Katia 
Published: August 2024

AbstractEwing sarcoma (EwS), a highly aggressive malignancy affecting children and young adults, is primarily driven by a distinctive oncogenic fusion, the EWSR1‐ETS, whose activity is a key source of epigenetic and clinical heterogeneity. CD99 is constantly present in EwS cells, known to modulate the EwS genetic profile and tumor malignancy. However, the relevance of CD99 alone, or in association with EWSR1‐ETS chimeras, is poorly understood. We explored the dynamic relationship between CD99 and EWS::FLI1, the main fusion observed in EwS, by means of model systems with inducible expression of either molecule. The transcriptomic dynamics of cells with or without expression of EWS::FLI1 or CD99 were analyzed and correlated with tumor cell growth. The CD99‐associated EwS gene profile was found to have commonalities with the profile induced by EWS::FLI1, but also peculiar differences. Both EWS::FLI1 and CD99 are regulated targets of the DREAM complex, but the CD99 expression specifically impacted genes that are the targets of FOXM1 and are involved in the setting of the G2/M phase of the cell cycle. Most CD99‐regulated FOXM1‐targeted genes were found to correlate with bad prognosis in two public clinical datasets (R2 platform), further supporting the clinical relevance of CD99‐mediated regulation of EwS gene expression.
Accurate Determination of the Uniaxial Complex Refractive Index and the Optical Band Gap of Polymer Thin Films to Correlate Their Absorption Strength and Onset of Absorption
Authors: Kamptner Alexander , Scharber Markus C. , Schiek Manuela 
Published: August 2024

AbstractThe advanced development of optoelectronic devices requires a methodical knowledge of the fundamental material properties of the key active components. Systematic investigations and correlations of such basic optical properties can lead to new insights for the design of more potent materials. In this perspective, we provide a systematic overview of the uniaxial anisotropic complex refractive indices and the absorption coefficients obtained by ellipsometry as well as the optical band gap energies derived from Tauc plots of six selected solution‐processed polymer thin films. While the optical band gap energies are intentionally distributed over the visible spectral range, we found that the absorption strength of all polymer samples are grouped in a random distribution within a rather uniform range of values.
Incorporating judgment in forecasting models in times of crisis
Authors: Franses Philip Hans 
Published: August 2024

AbstractThis paper introduces a simple and reproducible method to modify model forecasts using expert forecasts which is useful in crisis times. The idea is to add the expert forecast as an additional observation of the dependent variable, and to extend the model with an additional explanatory variable such as the square of a deterministic trend. Next, the new model forecast is combined with the expert forecast using equal weights. We show that it works well for gross domestic product growth forecasts for 2020 for 12 countries and that it improves upon an equal‐weighted combination of the original model forecast and expert forecast.
Integrated artificial intelligence and non‐similar analysis for forced convection of radially magnetized ternary hybrid nanofluid of Carreau‐Yasuda fluid model over a curved stretching surface
Authors: Jan Ahmed , Mushtaq Muhammad , Khan Muhammad Imran , Farooq Umer 
Published: August 2024

AbstractThe current study investigates the boundary layer flow of Carreau‐Yasuda (C‐Y) ternary hybrid nanofluid model in a porous medium across curved surface stretching at linear rate under the influence of applied radial magnetic field. , and are nanoparticles and ethylene glycol is considered as base fluid. The effects of viscous dissipation and ohmic heating are present in the energy equation. The governing partial differential equation (PDEs) is nondimensionalized using non‐similarity transformations. They can be treated as ordinary differential equations (ODEs) using local non‐similarity method and solutions are obtained via bvp4c MATLAB tools. The results are evaluated by introducing computational intelligence approach utilizing the AI‐based Levenberg–Marquardt scheme with a backpropagation neural network (LMS‐BPNN) to investigate flow stability. The authors intend to use AI‐based LMS‐BPNN is to optimize the behavior of the hybrid nanofluid (HNF) flow of Carreau‐Yasuda fluid across a stretching curved sheet. Initial/reference solutions are obtained through bvp4c function (an embedded MATLAB function designed to solve systems of ODEs) by systematically adjusting input parameters as demonstrated in Scenarios 1–5. There are three options to divide the numerical data: 80% for training, 10% for testing, and an additional 10% for validation. The LMS‐BPNN is used for approximate solutions of Scenario 1–5. The efficiency and reliability of LMS‐BPNN are validated through fitness curves based on correlation index (R), error, and regression analysis. The velocity and temperature profiles asymptotically satisfy boundary conditions of Scenario 1–5 with LMS‐BPNN.
A rare cause of hydronephrosis: Left retrocaval ureter without situs inversus or inferior vena cava duplication with CT and US imaging findings
Authors: Hasdemir Atilla , Atay Musa , Balkan Emine , İsleyen M. Edip , Unal İrem 
Published: August 2024

AbstractRetrocaval ureter is a rare congenital anomaly. It usually occurs on the right side and cases on the left side without accompanying conditions such as situs inversus or double inferior vena cava (IVC) are uncommon. Instances of left retrocaval ureter without situs inversus or double IVC are rarely reported in the literature, and there are no cases presented sonographically. In this case, we present a demonstrative sonographic and tomographic images of a left‐sided Type 1 retrocaval ureter case where situs inversus and double IVC were not present. In cases where hydronephrosis is detected on ultrasound, a medially displaced ureter should raise suspicion for retrocaval ureter.
Age‐, region‐, and day/night‐related variation of the chloride reversal potential in the rat suprachiasmatic nucleus
Authors: Osuna‐Lopez Fernando , Herrera‐Zamora J. Manuel , Reyes‐Méndez Miriam E. , Aguilar‐Roblero Raúl A. , Sánchez‐Pastor Enrique A. , Navarro‐Polanco Ricardo A. , Moreno‐Galindo Eloy G. , Alamilla Javier 
Published: August 2024

AbstractThe master control of mammalian circadian rhythms is the suprachiasmatic nucleus (SCN), which is formed by the ventral and dorsal regions. In SCN neurons, GABA has an important function and even excitatory actions in adulthood. However, the physiological role of this neurotransmitter in the developing SCN is unknown. Here, we recorded GABAergic postsynaptic currents (in the perforated‐patch configuration using gramicidin) to determine the chloride reversal potential (ECl) and also assessed the immunological expression of the Na‐K‐Cl cotransporter 1 (NKCC1) at early ages of the rat (postnatal days (P) 3 to 25), during the day and night, in the two SCN regions. We detected that ECl greatly varied with age and depending on the SCN region and time of day. Broadly speaking, ECl was more hyperpolarized with age, except for the oldest age studied (P20–25) in both day and night in the ventral SCN, where it was less negative. Likewise, ECl was more hyperpolarized in the dorsal SCN both during the day and at night; while ECl was more negative at night both in the ventral and the dorsal SCN. Moreover, the total NKCC1 fluorescent expression was higher during the day than at night. These results imply that NKCC1 regulates the circadian and developmental fluctuations in the [Cl−]i to fine‐tune ECl, which is crucial for either excitatory or inhibitory GABAergic actions to occur in the SCN.
“It made me feel more alive”: A qualitative analysis of quality of life improvements following completion of trauma‐focused therapy for posttraumatic stress disorder
Authors: Kehle‐Forbes Shannon M. , Baier Allison L. , Ackland Princess E. , Spoont Michele , Polusny Melissa A. , Schnurr Paula P. , Galovski Tara , Meis Laura 
Published: August 2024

AbstractPosttraumatic stress disorder (PTSD) is associated with poor quality of life. Although randomized clinical trial data show improvements in quality of life following trauma‐focused therapies (TFTs), including prolonged exposure therapy (PE) and cognitive processing therapy (CPT), less is known about how these improvements are experienced from the trauma survivor's perspective. A national sample of 60 veterans who recently completed TFT as part of routine care at U.S. Department of Veterans Affairs facilities participated in semistructured qualitative interviews during which the impact of treatment on quality of life was explored. Following a mixed deductive/inductive approach, six interrelated themes describing changes in quality of life emerged: full participation in social activities, greater emotional intimacy in relationships, improvements in parenting, expanded engagement in hobbies and community, increased occupational commitment and confidence, and more joy in life. The data highlight the positive impact of treatment on quality of life and provide depth to quantitative findings demonstrating improvements in quality of life following TFT.
Contrast‐Enhanced Ultrasound: A Real‐Time, Noninvasive, Radiation‐Free Method for Intraoperative Male Urethral Fistula Assessment
Authors: Lu Qijie , Liu Wei , Chen Lei 
Published: August 2024

ObjectivesTo evaluate the feasibility of intraoperative transurethral contrast‐enhanced ultrasound for the assessment of male urethral fistulas.MethodsPatients in a prospective database who underwent intraoperative two‐dimensional ultrasound, transurethral saline‐enhanced ultrasound, and contrast‐enhanced ultrasound between January 2017 and July 2022 were included. All patients were clinically diagnosed with urethral fistulae (UF) in the outpatient setting based on clinical presentations, traditional two‐dimensional ultrasound, and/or other imaging modalities and confirmed during surgical repair. Dynamic videos of the scans were independently analyzed by two experienced ultrasonologists.ResultsThirty‐nine patients with an average age of 51 years were included. The UF were located in the anterior urethra in 22 (56.4%) patients and in the bulbar urethra in 14 (63.6%) patients. UF were located in the posterior urethra in 17 (436%) patients and in the prostatic urethra in 13 (76.5%) patients. Contrast‐enhanced ultrasonography revealed UF in all patients. In patients with anterior UF, saline‐enhanced ultrasound images did not show a UF in 15 (68.2%, 15/22) patients, 13 (86.7%, 13/15) of whom had fistulae with diameters <3 mm. Saline‐enhanced ultrasound images did not reveal posterior UF in 13 (76.5%, 13/17) patients. The fistula diameters in eight (61.5%, 8/13) patients were <3 mm. The duration for contrast‐enhanced ultrasonography was approximately 3 minutes. The duration for surgical repair was approximately 2 hours.ConclusionsTransurethral contrast‐enhanced ultrasound is a real‐time, noninvasive, and radiation‐free method that allows intraoperative imaging and accurate assessment of male UF. Its sensitivity is higher than that of both two‐dimensional ultrasound and transurethral saline‐enhanced ultrasound. The location, size, and course of the fistulae can be clearly seen due to greater contrast during contrast‐enhanced ultrasound.
Species distribution models predict potential habitat for the endangered New Mexico jumping mouse
Authors: Martínez‐Fonseca José Gabriel , Westeen Erin P. , Jenness Jeff , Zahratka Jennifer L. , Chambers Carol L. 
Published: August 2024

AbstractThe New Mexico jumping mouse (Zapus luteus) is a federally endangered species that relies on riparian sites of the southwestern United States. Only isolated populations occur throughout its range and detecting potential suitable environments and identifying new populations are important for long‐term conservation of genetic diversity and habitat restoration by management agencies. We used a presence‐only data approach compiled from multiple surveys since 2000 in Arizona, Colorado, and New Mexico with bioclimatic and vegetation variables to generate species distribution models for the species. Our models predicted environmentally suitable areas outside the current species management units that could be prioritized in surveys. Our models also highlighted opportunities for collaboration among federal, state, tribal, and private landowners and managers to secure habitat and connectivity for the species and its long‐term survival.
Invasive Ponto‐Caspian amphipods are less carnivorous outside their native range
Authors: Copilaș‐Ciocianu Denis , Garbaras Andrius , Šidagytė‐Copilas Eglė 
Published: August 2024

AbstractA species' expansion beyond the native range is often assumed to be associated with an increased dietary niche breadth. However, empirical evidence remains limited due to a scarcity of studies comparing both the parental and invaded ranges. Here, we test the trophic niche expansion hypothesis by examining stable isotopes and functional morphology across native (NW Black Sea) and invaded (SE Baltic Sea) ranges of two amphipods, Dikerogammarus villosus and Pontogammarus robustoides, originating from the Ponto‐Caspian region—a major source of species invading Holarctic inland waters. Stable isotopes revealed that both species underwent a marked dietary niche contraction by becoming less carnivorous in the invaded range. This dietary shift was morphologically mirrored by an overall reduction of functional traits related to predation. The magnitude of dietary and morphological change was greater in D. villosus. Our findings indicate that previous experimental reports of aggressive predation in D. villosus reflect opportunistic foraging and align with local stable isotope studies which generally indicate a low trophic position. We conclude that Ponto‐Caspian species can undergo rapid dietary changes outside the native range, and that dietary niche expansion is not a prerequisite for successful non‐native establishment.
The effect of in‐situ fibrillated polytetrafluoroethylene on the rheological, mechanical, and foaming properties of polystyrene based nanocomposite foams
Authors: Zhou Minghao , Chen Shudong , Huang An 
Published: August 2024

AbstractPolystyrene/polytetrafluoroethylene (PS/PTFE) in‐situ fibrillated nanocomposites were prepared by melt blending using a HAAKE torque rheometer, and the effects of different contents of in‐situ nanofibrillated PTFE on the properties of PS/PTFE nanocomposites were studied. The results showed that PTFE was in‐situ nanofibrillation in the composites, and the toughness, energy storage modulus and complex viscosity of PS/PTFE nanocomposite are all improved. When the content of PTFE was 3 wt%, the elongation at break was the highest, which was three times that of neat PS. What is more, the addition of PTFE significantly improved the cell morphology of PS/PTFE nanocomposite foams by supercritical fluid foaming. The cell structure and morphology of PS/PTFE (3 wt%) nanocomposite foam was the best under 110°C foaming temperature, and the cell diameter and cell density were 3.27 μm and 1.11 × 1010 cells/cm3, respectively. In addition, the tensile strength of PS/PTFE nanocomposite foams increased from 35.4 MPa of neat PS foam to 39.6 MPa of PS/PTFE (3 wt%) foam.
Designing of carbon nanohorn‐based heterostructure for improved mechanical properties, flame retardancy, and hydrophobicity of composite aerogels
Authors: Xu Jie , Liu Xiangrong , Wang Li , Zhu Yingkun , Ao Xiang , Guo Fanhui , Xie Zhipeng , Liang Feng , Wang De‐Yi , Wu Jianjun 
Published: August 2024

AbstractDeveloping flame‐resistant thermal insulation aerogels with strong mechanical properties is crucial for addressing the fire hazards in high‐rise buildings. Carbon nanomaterials have garnered significant attention for enhancing the flame retardancy and mechanical properties of polymers due to their safety, nontoxicity, and low additions. In this work, the effect of single‐walled carbon nanohorns (SWCNHs) on the mechanical properties, thermal insulation properties, thermal stability, flame retardancy, and hydrophobicity of polyvinyl alcohol/KH560/phytic acid composite aerogel (PKASx) was investigated. By adjusting the concentration of SWCNHs, the mechanical properties of the aerogel were significantly improved, owing to robust interactions between SWCNHs and the matrix. However, a declining trend was observed in both the compressive modulus and specific modulus when the quantity of SWCNHs exceeded 0.3%. Simultaneously, the PKAS0.3 aerogel exhibited remarkable flame retardancy and self‐extinguishing characteristics. It possessed a high LOI value of 34.2 ± 0.2%, with a 25.2% reduction in pHRR and an 18.6% reduction in THR. Moreover, the analysis of TSP and SPR curves affirmed that the inclusion of SWCNHs effectively minimized the production of gaseous by‐products during combustion. In addition, the introduction of SWCNHs introduced a trade‐off in the roughness of the aerogel. The maximum contact angle occurred at the optimal concentration of SWCNHs.
Visual detection of fungicide resistance by combining RPA and CRISPR/Cas12a in peach Brown rot fungus Monilinia fructicola
Authors: Liu Duo , Luo Mei , Zhu Yong‐Xu , Zeng Zhe‐Zheng , Hu Jia‐Jie , Cai Min‐Zheng , Wang Jing , Yin Wei‐Xiao , Schnabel Guido , Luo Chao‐Xi 
Published: August 2024

AbstractBACKGROUNDPeach brown rot caused by Monilinia fructicola severely affects the quality and yield of peach, resulting in large economic losses worldwide. Methyl benzimidazole carbamate (MBC) fungicides and sterol demethylation inhibitor (DMI) fungicides are among the most applied chemical classes used to control the disease but resistance in the target pathogen has made them risky choices. Timely monitoring of resistance to these fungicides in orchards could prevent control failure in practice.RESULTSIn the current study, we developed methods based on recombinase polymerase amplification (RPA) and CRISPR/Cas12a systems to detect MBC and DMI resistance based on the E198A mutation in the β‐tubulin (MfTub2) gene and the presence of the Mona element in the upstream region of the MfCYP51, respectively. For MBC resistance, RPA primers were designed that artificially incorporated PAM sites to facilitate the CRISPR/Cas12a reaction. Subsequently, specific tcrRNAs were designed based on the E198A mutation site. For the detection of the Mona element, we designed RPA primers M‐DMI‐F2/M‐DMI‐R1 that in combination with crRNA1 detected ‘Mona’ and distinguished resistant from sensitive strains.CONCLUSIONBoth methods exhibited high sensitivity and specificity, requiring only a simple isothermal device to obtain results within 1 h at 37 °C. The FQ‐reporter enabled visualization with a handheld UV or white light flashlight. This method was successfully used with purified DNA from lab cultures and crude DNA from symptomatic fruit tissue, highlighting its potential for on‐site detection of resistant strains in orchards. © 2024 Society of Chemical Industry.
Resource reallocation across successive systemic innovations: How Rolls‐Royce shaped the evolution of the turbojet, turboprop, and turbofan
Authors: Cattani Gino , Mastrogiorgio Mariano , Carignani Giuseppe 
Published: August 2024

AbstractResearch SummaryDespite the importance of resource reallocation in shaping a variety of strategic outcomes, strategy scholars have paid only limited attention to the processes by which firms reallocate their resources across successive systemic innovations. To explore these processes, we conducted an in‐depth historical case study on Rolls‐Royce's role in three distinct systemic innovations that marked the transition from piston engines to jet engines in the civil aviation industry: the turbojet, the turboprop, and the turbofan. The analysis helps explain how and why Rolls‐Royce's central role stemmed from its ability to reallocate existing non‐scale free organizational and technical resources. A key finding of this study is the identification of the horizontal transfer of functional modules as a critical process, especially during the incipient phase of a systemic innovation. The analysis also highlights the role that specific organizational arrangements, particularly a firm's integrative capabilities, have in shaping the effectiveness with which resources are reallocated.Managerial SummaryFocusing on resource reallocation is important to understand why some firms effectively reallocate their resources through successive systemic innovations while others cannot, even if they have similar resources and face the same environmental conditions. By delving into the technological aspects of aeroengine development and exploring why Rolls‐Royce had the capabilities to successfully integrate key functional modules across various modular levels, we clarify the relationship between technology and organization that underlies resource reallocation—a topic that has received only scant attention in the strategy literature.