bluuebunny/crossref_metadata_2025_split huggingface dataset:
Endothelial cell division in angiogenic sprouts of differing cellular architecture
Authors: Aydogan Vahap , Lenard Anna , Denes Alexandru Stefan , Sauteur Loic , Belting Heinz-Georg , Affolter Markus 
Published: September 2015

ABSTRACT
The vasculature of the zebrafish trunk is composed of tubes with different cellular architectures. Unicellular tubes form their lumen through membrane invagination and transcellular cell hollowing, whereas multicellular vessels become lumenized through a chord hollowing process. Endothelial cell proliferation is essential for the subsequent growth and maturation of the blood vessels. However, how cell division, lumen formation and cell rearrangement are coordinated during angiogenic sprouting has so far not been investigated at detailed cellular level. Reasoning that different tubular architectures may impose discrete mechanistic constraints on endothelial cell division, we analyzed and compared the sequential steps of cell division, namely mitotic rounding, cytokinesis, actin re-distribution and adherence junction formation, in different blood vessels. In particular, we characterized the interplay between cell rearrangement, mitosis and lumen dynamics within unicellular and multicellular tubes. The lumen of unicellular tubes becomes constricted and is ultimately displaced from the plane of cell division, where a de novo junction forms through the recruitment of junctional proteins at the site of abscission. By contrast, the new junctions separating the daughter cells within multicellular tubes form through the alteration of pre-existing junctions, and the lumen is retained throughout mitosis. We also describe variations in the progression of cytokinesis: while membrane furrowing between daughter cells is symmetric in unicellular tubes, we found that it is asymmetric in those multicellular tubes that contained a taut intercellular junction close to the plane of division. Our findings illustrate that during the course of normal development, the cell division machinery can accommodate multiple tube architectures, thereby avoiding disruptions to the vascular network.
Modeling dioxygenase enzyme kinetics in familial paraganglioma
Authors: Peters Justin P. , Her Yeng F. , Maher L. James 
Published: September 2015

ABSTRACT
Hypoxia inducible factors (HIFs) play vital roles in cellular maintenance of oxygen homeostasis. These transcription factors are responsible for the expression of genes involved in angiogenesis, metabolism, and cell proliferation. Here, we generate a detailed mathematical model for the enzyme kinetics of α-ketoglutarate-dependent HIF prolyl 4-hydroxylase domain (PHD) dioxygenases to simulate our in vitro data showing synergistic PHD inhibition by succinate and hypoxia in experimental models of succinate dehydrogenase loss, which phenocopy familial paraganglioma. Our mathematical model confirms the inhibitory synergy of succinate and hypoxia under physiologically-relevant conditions. In agreement with our experimental data, the model predicts that HIF1α is not stabilized under atmospheric oxygen concentrations, as observed. Further, the model confirms that addition of α-ketoglutarate can reverse PHD inhibition by succinate and hypoxia in SDH-deficient cells.
Reviews Books
Authors: Boyd Gregory , Kouchakji Kristi , Norton Bryan , Okuyama Chika , Sherry Joseph 
Published: September 2015

Abstract
Hitchcock's Partner in Suspense: The Life of Screenwriter Charles Bennett, John Charles Bennett, (2014) Lexington: University Press of Kentucky, 279pp., ISBN: 9780813144498 (hbk), $40.00
Creating the Witness: Documenting Genocide on Film, Video, and the Internet, Leshu Torchin, (2012) Minneapolis: University of Minnesota Press, 296pp., ISBN: 978081667623 (pbk), $25.00 , ISBN: 9780816676224 (hbk), $75.00
Subjective Realist Cinema: From Expressionism to Inception, Matthew Campora, (2014) New York: Berghahn, 160pp., ISBN: 2013023314 (hbk), $49.95
China's iGeneration: Cinema and Moving Image Culture for the Twenty-First Century, Matthew D. Johnson, Keith B. Wagner, Tianqi Yu, and Luke Vulpiani (eds), (2014) London: Bloomsbury Books, 368pp., ISBN: 9781623565944 (hbk), $140.00, ISBN: 9781623565954 (eBook), $125.99
Saying It With Songs: Popular Music and the Coming of Sound to Hollywood Cinema, Katherine Spring, (2013) New York: Oxford University Press, 229pp., ISBN: 0199842221 (pbk), $29.95, ISBN: 9780199842221 (hbk), $99.00
The Current State of Counternarcotics Policy and Drug Reform Debates in Myanmar
Authors: Kramer Tom 
Published: September 2015

AbstractMyanmar is the world’s second largest producer of opium after Aghanistan. Following a decade of decline, cultivation has more than doubled since 2006. The production and use of amphetamine-type stimulants (ATS) is also rising. Most of the opium is turned into heroin and exported via neighboring countries, especially to China. Decades of civil war and military rule have stimulated drug production and consumption, and marginalized ethnic communities. Myanmar has high levels of injecting drug users infected with HIV/AIDS and hepatitis C. Drug policies in Myanmar are repressive and outdated, with an ineffective focus on arresting drug users and eradicating poppy fields. The central government is unable to provide quality treatment for drug users. Past political repression and human rights violations by the military government caused an international boycott which prevented international donors from providing assistance. The reform process by the new quasi-civilian government includes both a peace process to end the civil war and a review of the country’s drug laws, raising hope for more effective and humane drug policies.
Crystal structure of 3-(benzoylamino)azepan-2-one, C13H16N2O2
Authors: Li Xiao-Lin , Fang Zheng , Zhang Feng , Wang Meng-Xue , Guo Kai 
Published: September 2015

Abstract C13H16N2O2, orthorhombic, P212121 (no. 19), a = 7.488(2) Å, b = 9.633(2) Å, c = 16.933(3) Å, V = 1221.4 Å3, Z = 4, Rgt(F) = 0.0671, wRref(F2) = 0.1661, T = 293 K.
Crystal structure of tetra-aqua-bis(µ2-thiophene-3,4-dicarboxylato-κ4O,O’:O’’,O’’’)-bis(thiophene-3-carboxyl-4-carboxylato-κ1O)-bis(1,10- phenantroline-κ2N,N’)disamarium(III), C24H17N2O10S2Sm
Authors: Chen Shi-Jun , Li Shi-Hui 
Published: September 2015

Abstract C24H17N2O10S2Sm, triclinic, P1̅ (no. 2), a = 10.135(5) Å, b = 10.697(5) Å, c = 11.823(7) Å, ɑ = 94.676(5)°, β = 98.927(5)°, γ = 101.736(4)°, V = 1231.3 Å3, Z = 2, Rgt(F) = 0.0184, wRref(F2) = 0.0455, T = 296 K.
Crystal structure of 3-bromo-4,6-dibenzyloxy-2-hydroxy acetophenone, C22H19BrO4
Authors: Hill Tania N. , Kuo Chen-Miao , Bezuidenhoudt Barend C. B. 
Published: September 2015

Abstract C22H19BrO4, triclinic, P1̅ (no. 2), a = 8.550(2) Å, b = 11.343(2) Å, c = 11.715(2) Å, ɑ = 102.02(3)°, β = 110.47(3)°, γ = 110.84(3)°, V = 920.2 Å3, Z = 2, Rgt(F) = 0.0368, wRref(F2) = 0.099, T = 100 K.
Crystal structure of 3,5-bis(imidazole-1-yl)pyridine, C11H9N5
Authors: Hongyan Zhou 
Published: September 2015

Abstract C11H9N5, monoclinic, P21/c (no. 14), a = 14.15(1) Å, b = 3.783(3) Å, c = 18.09(2) Å, β = 92.28(2)°, V = 968.0 Å3, Z = 4, Rgt(F) = 0.0517, wRref(F2) = 0.1504, T = 296 K.
Crystal structure of [bis(benzimidazol-2-yl-methyl)amine-κ3N,N',N''] phthalato-κ2O,O' copper(II) — methanol— water (1:1:2), C25H27CuN5O7
Authors: Su Guo-Hua , Liu Yan-Peng , Chen Xuan , Nie Feng-Mei 
Published: September 2015

Abstract C25H27CuN5O7, triclinic, P1̅ (no. 2), a = 9.3812(6) Å, b = 11.3399(6) Å, c = 13.0957(8) Å, α = 81.654(8)°, β = 71.623(6)°, γ = 69.745(6)°, V = 1239.3 Å3, Z = 2, Rgt(F) = 0.0361, wRref(F2) = 0.0830, T = 99 K.
Crystal structure of trans-diaquabis(salicylaldehydato-κ2O,O') cobalt(II), C14H14CoO6
Authors: Diao Haipeng , Liu Wen , Zhou Min , Jia Bin , Xie Jun , Wang Haojiang , Sun Tijian 
Published: September 2015

Abstract C14H14CoO6, monoclinic, C2/m (no. 12), a = 7.3910(5) Å, b = 7.4029(6) Å, c = 13.012(1) Å, β = 90.573(1)°, V = 711.9 Å3, Z = 2, Rgt(F) = 0.0373, wRref(F2) = 0.1026, T = 298 K.
Crystal structure of poly[[µ2-1,2-benzenedicarboxylato-κ4O,O':O'',O''']- [µ2-2-((1H-imidazol-1-yl)-6-methyl)-1H-benzoimidazole-κ2N:N']- cadmium(II)], C20H15CdN4O4
Authors: Liang Zhen , Jian Shou-Jun , Zhou Jin-Huan , Yang Huai-Xia 
Published: September 2015

Abstract C20H15CdN4O4, triclinic, P1̅ (no. 2), a = 9.927(2) Å, b = 9.970(2) Å, c = 11.046(2) Å, ɑ = 80.94(3)°, β = 75.54(3)°, γ = 68.27(3)°, V = 980.8(3) Å3, Z = 2, Rgt(F) = 0.0281, wRref(F2) = 0.0703, T = 293 K.
Crystal structure of catena-poly[diaqua-3-(4-fluoro-phenyl)-acrylate-κ2O,O'-bis(κ2O,O')-1,2-di(4-pyridyl)ethylene-κ2N:N'nickel(II)] 3-(4- fluoro-phenyl)-acrylate, C30H26F2N2NiO6
Authors: Kang Hai-Xia , Duan Yu-Hao , Yang Rui-Juan , Fu Yu-Qin 
Published: September 2015

Abstract C30H26F2N2NiO6, monoclinic, P21/c (no. 14), a = 16.6375(6) Å, b = 6.7702(3) Å, c = 25.352(1) Å, β = 105.390(1)°, V = 2753.2 Å3, Z = 4, Rgt(F) = 0.0325, wRref(F2) = 0.0781, T = 296 K.
Reasons for Rehospitalization in Children Who Had Neonatal Abstinence Syndrome
Authors: Uebel Hannah , Wright Ian M. , Burns Lucy , Hilder Lisa , Bajuk Barbara , Breen Courtney , Abdel-Latif Mohamed E. , Feller John M. , Falconer Janet , Clews Sarah , Eastwood John , Oei Ju Lee 
Published: September 2015

BACKGROUND AND OBJECTIVES:
Neonatal abstinence syndrome (NAS) occurs after in utero exposure to opioids, but outcomes after the postnatal period are unclear. Our objectives were to characterize childhood hospitalization after NAS.

METHODS:
Population-based linkage study of births, hospitalization, and death records of all children registered in New South Wales (NSW), Australia, between 2000 and 2011 to a maximum of 13 years. Infants with an International Statistical Classification of Disease and Related Problems, 10th Edition, Australian Modification, coding of NAS (P96.1, n = 3842) were compared with 1 018 421 live born infants without an NAS diagnosis.

RESULTS:
Infants with NAS were more likely to be admitted into a nursery (odds ratio 15.6, 95% confidence interval: 14.5–16.8) and be hospitalized longer (10.0 vs 3.0 days). In childhood, they were more likely to be rehospitalized (1.6, 1.5–1.7), die during hospitalization (3.3, 2.1–5.1), and be hospitalized for assaults (15.2, 11.3–20.6), maltreatment (21.0, 14.3–30.9), poisoning (3.6, 2.6–4.8), and mental/behavioral (2.6, 2.1–3.2) and visual (2.9, 2.5-3.5) disorders. Mothers of infants with NAS were more likely to be Indigenous (6.4, 6.0–7.0), have no antenatal care (6.6, 5.9–7.4), and be socioeconomically deprived (1.6, 1.5–1.7). Regression analyses demonstrated that NAS was the most important predictor of admissions for maltreatment (odds ratio 4.5, 95% confidence interval: 3.4–6.1) and mental and behavioral disorders (2.3, 1.9–2.9), even after accounting for prematurity, maternal age, and Indigenous status.

CONCLUSIONS:
Children with NAS are more likely to be rehospitalized during childhood for maltreatment, trauma, and mental and behavioral disorders even after accounting for prematurity. This continues to adolescence and emphasizes the critical need for continued support of this vulnerable group after resolution of NAS.
Family Experience and PICU Death: A Meta-Synthesis
Authors: Butler Ashleigh E. , Hall Helen , Willetts Georgina , Copnell Beverley 
Published: September 2015

BACKGROUND AND OBJECTIVES:The PICU is the most common site for inpatient pediatric deaths worldwide. The impact of this clinical context on family experiences of their child’s death is unclear. The objective of the study was to review and synthesize the best available evidence exploring the family experience of the death of their child in the PICU.METHODS:Studies were retrieved from CINAHL Plus, OVID Medline, Scopus, PsycINFO, and Embase. Gray literature was retrieved from greylit.com, opengrey.edu, Trove, Worldcat, and Google scholar. Study selection was undertaken by 4 reviewers by using a multistep screening process, based on a previously developed protocol (International Prospective Register of Systematic Reviews 2015:CRD42015017463). Data was extracted as first-order constructs (direct quotes) or second-order constructs (author interpretations) onto a predeveloped extraction tool. Data were analyzed by thematic synthesis.RESULTS:One main theme and 3 subthemes emerged. “Reclaiming parenthood” encompasses the ways in which the parental role is threatened when a child is dying in the PICU, with the subthemes “Being a parent in the PICU,” “Being supported,” and “Parenting after death” elucidating the ways parents work to reclaim this role. The review is limited by a language bias, and by the limitations of the primary studies.CONCLUSIONS:When a child dies in a PICU, many aspects of the technology, environment, and staff actions present a threat to the parental role both during and after the child’s death. Reclaiming this role requires support from health care providers and the wider community.
Soybean Quantitative Trait Loci Conditioning Soybean Rust‐Induced Canopy Damage
Authors: Harris Donna K. , Abdel‐Haleem Hussein , Buck James W. , Phillips Daniel V. , Li Zenglu , Boerma H. Roger 
Published: September 2015

ABSTRACTSoybean rust (SBR) is caused by the fungal pathogen Phakopsora pachyrhizi and is considered to be the most destructive foliar disease of soybean [Glycine max (L.) Merr.], with soybean yield losses caused by SBR reported to be as high as 80% in severely diseased fields. Studies indicate that most isolates of P. pachyrhizi overcome at least one of the known resistance genes. Therefore, alternative means of controlling SBR such as non‐host‐specific resistance combined with single‐gene resistance could be beneficial in breeding soybean cultivars for SBR resistance. To identify quantitative trait loci (QTL) conditioning variation in SBR‐induced canopy damage, a ‘Benning’ × PI 416947 recombinant inbred line population was planted for 3 yr under natural and artificial infection with P. pachyrhizi in Attapulgus, GA. Although both Benning and PI 416937 are considered susceptible to SBR (they produced tan lesions when infected with P. pachyrhizi), Benning had a higher canopy severity damage score than PI 416937. Multiple interval mapping QTL models identified four QTL conditioning variation in canopy severity damage across the environments and explained 42% of the total phenotypic variation in canopy severity scores. The four QTL were located on chromosomes 8, 9, 13, and 15, which explained 10, 5, 9, and 17% of the phenotypic variation, respectively. When the canopy severity QTL were aligned with previously identified QTL in SoyBase, three canopy severity QTL colocalized with other partial resistance soybean genes and three with the isoflavone daidzein, the precursor of the phytoalexin glyceollin. Glyceollin is involved in plant disease resistance.
Reporting Frequency and Presentation Format: Detecting Real Activities Manipulation
Authors: Tang Fengchun , Eller Christopher Kevin , Wier Benson 
Published: September 2015

ABSTRACT
As management increasingly manages earnings through real activities manipulation (RAM), RAM detection has become an important issue. This study investigates the role of reporting frequency and presentation format in detecting sales-related RAM. Based on the results of an online experiment with 77 experienced financial analysts, we find that more frequent financial reporting significantly improves sales-related RAM detection when financial analysts are aided with graphical displays. The results of our study suggest that more frequent financial reporting has the potential to improve RAM detection by disclosing trends that are suggestive of RAM. Moreover, results indicate that graphical representation reduces the cognitive effort required to process a larger number of data points generated by more frequent reporting and thus provides a better cognitive fit than tabular representation. As a result, the combination of more frequent reporting and graphical support together may assist financial statement users in detecting certain types of RAM.
Mediterranean Diet, Retinopathy, Nephropathy, and Microvascular Diabetes Complications: A Post Hoc Analysis of a Randomized Trial
Authors: Díaz-López Andrés , Babio Nancy , Martínez-González Miguel A. , Corella Dolores , Amor Antonio J. , Fitó Montse , Estruch Ramon , Arós Fernando , Gómez-Gracia Enrique , Fiol Miquel , Lapetra José , Serra-Majem Lluís , Basora Josep , Basterra-Gortari F. Javier , Zanon-Moreno Vicente , Muñoz Miguel Ángel , Salas-Salvadó Jordi ,   the PREDIMED Study Investigators
Published: September 2015

OBJECTIVE
To date no clinical trials have evaluated the role of dietary patterns on the incidence of microvascular diabetes complications. We hypothesized that a nutritional intervention based on the Mediterranean diet (MedDiet) would have greater protective effect on diabetic retinopathy and nephropathy than a low-fat control diet.

RESEARCH DESIGN AND METHODS
This was a post hoc analysis of a cohort of patients with type 2 diabetes participating in the PREvención con DIeta MEDiterránea (PREDIMED) study, a multicenter randomized nutritional intervention trial conducted in a population at high cardiovascular risk. Individuals with type 2 diabetes who were free of microvascular complications at enrollment (n = 3,614, aged 55–80 years) were randomly assigned to one of three dietary interventions: MedDiet supplemented with extravirgin olive oil (MedDiet+EVOO), MedDiet supplemented with mixed nuts (MedDiet+Nuts), or a low-fat control diet. Two independent outcomes were considered: new onset of diabetic retinopathy and nephropathy. Hazard ratios (HRs) were calculated using multivariable-adjusted Cox regression.

RESULTS
During a median follow-up of 6.0 years, we identified 74 new cases of retinopathy and 168 of nephropathy. Compared with the control diet, multivariable-adjusted HRs for diabetic retinopathy were 0.56 (95% CI 0.32–0.97) for the MedDiet+EVOO and 0.63 (0.35–1.11) for the MedDiet+Nuts. No between-group differences were found for nephropathy. When the yearly updated information on adherence to the MedDiet was considered, the HR for retinopathy in the highest versus the lowest quintile was 0.34 (0.13–0.89; P = 0.001 for trend). No significant associations were found for nephropathy.

CONCLUSIONS
A MedDiet enriched with EVOO may protect against diabetic retinopathy but not diabetic nephropathy.
A Call for Evidence-based Decision Making When Selecting Outcome Measurement Instruments for Summary of Findings Tables in Systematic Reviews: Results from an OMERACT Working Group
Authors: Beaton Dorcas E. , Terwee Caroline B. , Singh Jasvinder A. , Hawker Gillian A. , Patrick Donald L. , Burke Laurie B. , Toupin-April Karine , Tugwell Peter S. 
Published: September 2015

Objective.Systematic reviews often struggle with how to combine information when more than 1 instrument is used across studies being synthesized. Different techniques have been suggested based on frequency of use in the literature, or on consensus. We explore an approach blending 2 initiatives: OMERACT (Outcome Measurement in Rheumatology) and COSMIN (Consensus On Selection of Measurement Instruments), and investigate the effects of an evidence-based measurement approach on selection of outcomes.Methods.Readings were circulated to attendees registered for a preconference workshop on pain measurement. Three instruments were considered and exercises conducted to engage people in the content and measurement performance of these tools. Consensus was sought that an evidence-based approach could be created for selection of instruments for summary of findings (SoF) tables.Results.The blending of COSMIN and OMERACT approaches led to an evidence-based approach that depended both on a clear definition of target concept and a review of measurement performance of the instrument. Participants emphasized that conceptual clarity and practical considerations should come before measurement property results.Conclusion.Evidence-based approaches can be adopted for selection of instruments for SoF tables. A research agenda was formulated.
Les littératures africaines
Authors: Moulard-Kouka Sophie 
Published: September 2015

Le travail qu’Alain Ricard a entrepris dans les années 70 a contribué à voir émerger un champ de recherche aujourd’hui en plein essor : celui des cultures populaires et des pratiques performatives en Afrique subsaharienne. Il s’est intéressé notamment à leur aspect textuel, aux ressources langagières qu’elles mettent en œuvre, non seulement comme expression d’une poétique, mais aussi comme discours prononcé sur la société. Consécutivement à une réflexion sur la définition de ce champ et sur sa terminologie, je m’attacherai à montrer quel est l’intérêt de poursuivre dans cette voie. Les pratiques performatives sont le lieu d’une énonciation du politique et d’une mise en scène des rapports de pouvoir, qu’il est intéressant d’analyser dans les textes, dans la poïétique et dans la performance. Je présenterai enfin de manière ethnographique le cas du rap dakarois, sur lequel j’ai mené une longue enquête de terrain.
Les littératures africaines
Authors: Englert Birgit 
Published: September 2015

Le Bongo Flava , actuellement la musique la plus populaire en Tanzanie, ne se limite plus à Dar es-Salaam, la métropole tanzanienne où ce genre basé sur le hip-hop a commencé dans les années 1990. Partout dans le pays, des jeunes qui se regardent comme faisant partie de « la nouvelle génération » écrivent eux-mêmes des textes ( mashairi ) en Swahili. Bien que peu entre eux réussissent à enregistrer une chanson ou même à être écoutés à la radio ou à la télévision, ces chansons, et de plus en plus aussi des vidéos, circulent au niveau local et y sont bien connues et mémorisées. Cette contribution offre une description du contexte de la production de ces produits culturels au sud de la Tanzanie, dans les petites villes de Masasi (région Mtwara) et de Nachingwea (région Lindi) où les jeunes (presque exclusivement des hommes) adoptent les possibilités offertes par les nouvelles technologies pour se faire écouter, surtout par les générations de leurs parents et grands-parents. Ainsi, ils ne changent pas seulement les relations entre les générations, mais aussi la géographie culturelle du pays en transformant des lieux considérés comme « périphériques » du point de vue géographique et économique en centres locaux de production de la culture populaire.
Les littératures africaines
Authors: Derive Jean 
Published: September 2015

Cette contribution s’intéresse, dans un esprit comparatiste, aux analogies transculturelles, dans le temps et dans l’espace (mais aussi à leurs limites) à propos de certaines notions de l’histoire littéraire générale. C’est ainsi qu’y est examiné dans quelle mesure le concept d’« idéal classique », né dans le contexte de la culture occidentale à une certaine époque, peut aussi s’avérer pertinent, lorsqu’il est appliqué à un terrain africain d’une autre époque, pour aider à comprendre certaines aspirations de la production littéraire en cette zone de culture spécifique. Sont notamment abordées les questions de l’idéal mimétique et de l’aspiration à l’universel, qui ont été les deux composantes essentielles d’un tel concept en Occident, afin d’examiner comment elles se posent dans ce nouveau contexte géopolitique.
Les littératures africaines
Authors: Nzabatsinda Anthère 
Published: September 2015

Si l’on tient compte de l’évolution des recherches sur l’Afrique et que l’on envisage un rapprochement entre l’anthropologie et les études littéraires, le travail de l’écrivain du Rwanda, l’abbé Alexis Kagame, montre avec pertinence la perspective à la fois philologique et territoriale de son œuvre. Et c’est un sens similaire qu’Alain Ricard a souligné dans son étude consacrée au processus de passage « des langues aux livres ». Notre contribution au présent volume d’hommage pour l’africaniste Alain Ricard voudrait donner quelques exemples du travail d’Alexis Kagame, écrivain de la tradition africaine, artisan philologue, entre autres, de la langue et de la littérature poétique du territoire culturel, anthropologique et littéraire du Rwanda.