bluuebunny/crossref_metadata_2025_split huggingface dataset:
“It Attracts Your Eyes and Brain”: Refining Visualizations for Shared Decision-Making with Heart Failure Patients
Authors: Mangal Sabrina , Hyder Maryam , Zarzuela Kate , McDonald William , Masterson Creber Ruth M. , Kronish Ian M. , Konigorski Stefan , Maurer Mathew S. , Safford Monika M. , Lachs Mark S. , Goyal Parag 
Published: August 2024

Abstract
Background N-of-1 trials have emerged as a personalized approach to patient-centered care, where patients can compare evidence-based treatments using their own data. However, little is known about optimal methods to present individual-level data from medication-related N-of-1 trials to patients to promote decision-making.
Objectives We conducted qualitative interviews with patients with heart failure with preserved ejection fraction undergoing N-of-1 trials to iterate, refine, and optimize a patient-facing data visualization tool for displaying the results of N-of-1 medication trials. The goal of optimizing this tool was to promote patients' understanding of their individual health information and to ultimately facilitate shared decision-making about continuing or discontinuing their medication.
Methods We conducted 32 semistructured qualitative interviews with 9 participants over the course of their participation in N-of-1 trials. The N-of-1 trials were conducted to facilitate a comparison of continuing versus discontinuing a β-blocker. Interviews were conducted in person or over the phone after each treatment period to evaluate participant perspectives on a data visualization tool prototype. Data were coded using directed content analysis by two independent reviewers and included a third reviewer to reach a consensus when needed. Major themes were extracted and iteratively incorporated into the patient-facing data visualization tool.
Results Nine participants provided feedback on how their data were displayed in the visualization tool. After qualitative analysis, three major themes emerged that informed our final interface. Participants preferred: (1) clearly stated individual symptom scores, (2) a reference image with labels to guide their interpretation of symptom information, and (3) qualitative language over numbers alone conveying the meaning of changes in their scores (e.g., better, worse).
Conclusion Feedback informed the design of a patient-facing data visualization tool for medication-related N-of-1 trials. Future work should include usability and comprehension testing of this interface on a larger scale.
Synthesis of Cyclobutanes and Cyclobutenes by Strain-Release-Driven Ring-Opening of Bicyclo[1.1.0]butanes
Authors: Zhan Xuan , He Heng-Xian , Peng Quanxin , Feng Jian-Jun 
Published: August 2024

AbstractCyclobutanes and cyclobutenes exhibit intriguing structures and demonstrate significant biological activities and diverse synthetic applications. This review aims to summarize recent progress in strain-release-driven ring-opening reactions of bicyclo[1.1.0]butanes (BCBs) to synthesize these four-membered carbon rings. It outlines the strategies, regio- and stereoselectivity, the synthetic scope of reactions, and the mechanistic implications of the catalytic ring-opening process, providing a supplementary perspective to existing reviews.1	Introduction2	Thermally Driven Nucleophilic Ring-Opening3	Thermally Driven Rearrangement and Isomerization Reaction4	Light-Driven Ring-Opening5	Transition-Metal/Lewis Acid Catalyzed Ring-Opening6	Conclusion and Outlook
A rigid and compact piezoelectric motor with high output efficiency
Authors: Touqeer Muhammad , Maqbool Syed Asad , Esmaeilzadeh Behnam , Zheng Shaofeng , Meng Wenjie , Abas Asim , Wang Jihao , Feng Qiyuan , Hou Yubin , Lu Qingyou 
Published: August 2024

We introduce a novel piezoelectric stepper motor featuring high compactness, rigidity, and any direction operability. Here, not only is the structure of high novelty but also the working principle very simple. The piezo stacks unit is sandwiched between two spring finger pieces, with almost equal clamping forces applied between the top of the piezo stacks’ unit and the spring finger piece. Applying individual driving signals to each of the five piezo stack pairs, causing deformation one by one in the same direction, followed by simultaneous recovery in the reverse direction, enables movement of the frame part. The optimized clamping force of the piezoelectric stack units and spring fingers ensures maximum output force. The motor’s operational capability at low threshold voltages, specifically 8 V for downward movement and 10 V for upward movement, confirmed its efficacy in both vertical and horizontal directions. The motor’s operational capability at a low threshold voltage of 10 V confirmed its efficacy in both vertical and horizontal directions. At room temperature, step size ranges from 0.3 to 7.4 µm at 20 Hz frequency and varying driving voltage from 10 to 180 V. It has a maximum travel range of about 5 mm and can lift a maximum load of 220 g in an upward direction, so the maximum output force generated by this motor is 2.2 N. The compact and rigid design is capable of building an atomically resolved scanning probe microscope, and its working ability has the potential to use the cleavage of different types of samples in limited space environments, such as the small-bore superconducting magnet and low temperature.
Design and initial results of the imaging neutral particle analyzer in large helical device
Authors: Paenthong W. , Ogawa K. , Sangaroon S. , Du X. D. , Liu D. , Liao L. Y. , Wisitsorasak A. , Onjun T. , Isobe M. 
Published: August 2024

A novel Imaging Neutral Particle Analyzer (INPA) was newly installed in early 2024 to enhance the understanding of fast ion confinement on Large Helical Devices (LHDs). This diagnostic system, based on a magnetic spectrometer using a scintillator, provides energy-resolved radial profiles of confined fast ions by measuring charge-exchanged fast neutrals escaping from the plasma. The system utilizes a 100 nm thick carbon foil to ionize the fast neutrals, subsequently deflecting the ions toward a scintillator via the existing local magnetic field. The fast ion energy and sightline determine the position of the scintillation, while the light intensity depends on the flux of the fast ions. The INPA features two apertures, facilitating effective measurements in both clockwise and counterclockwise magnetic field directions in the LHD. This INPA was designed as a passive measurement system that measures fast ions charge exchange with background neutrals, focusing on perpendicular beam ions from 5 to 100 keV with an energy resolution of about 5.75 keV. This paper describes the details of the design, installation, and the initial results of the INPA on the LHD. This work will contribute significantly to a deeper understanding of fast ion transport due to magnetohydrodynamic instabilities.
Gallium oxide (Ga2O3) energy dependent scintillation response to fast neutrons and flash gamma-rays
Authors: Valdes D. J. , Miller S. , Leak C. , Haque S. , Gunthoti K. , Wender S. A. , Paneru S. , Lee H.-Y. , Vogel S. C. , Sun K.-X. 
Published: August 2024

Gallium oxide is a newly emerged ultrawide bandgap (4.9 eV) semiconductor that is suitable as a combined electronics and radiation detection platform. We have experimentally demonstrated fast neutron and gamma-ray scintillation from Czochralski-grown β-Ga2O3 in a recent series (October 2023) of experiments at the unmoderated pulsed neutron spallation source located at the Los Alamos Neutron Science Center. Using the neutron time-of-flight (TOF) technique and a fast-gated intensified CCD camera, we observed energy-dependent neutron scintillation for neutron energies ranging from 1 to 400 MeV, including the 14.1 MeV neutron energy relevant to D–T fusion. Neutron flux is quantified and calibrated by cascading the scintillator after the fission chamber, enabling a detailed analysis of temporal and energy-dependent characteristics of the scintillation events. A pronounced scintillation signal from the spallation gamma flash with a temporal full width of half maximum of ∼4 ns is indicative of the material’s rapid response. Neutron energy dependent scintillation is observed using the TOF method at a 22.6-m distance from the neutron source. These results highlight the possibility of developing a Ga2O3 based fusion neutron diagnostic platform integrated with both scintillation and electronics functions on the integrated chip scale.
Environmental temperature influences detectability of a nocturnal marsupial
Authors: Kowalick Gillian N. , Ross Alexandra K. , Crisp Helen A. 
Published: August 2024

Mammals have a range of strategies designed to maintain optimal body temperature regardless of environmental temperature. One energy-efficient strategy is to avoid environmental temperature extremes by modifying active periods. Reduced animal activity can result in fewer detections of target species during surveys that require direct observation of individuals. Observations of the greater bilby (Macrotis lagotis) from 8 years of survey data were investigated to determine the impact of environmental temperature and season on bilby detectability. Bilby observations were positively correlated with temperature regardless of season. Wildlife managers should consider minimum environmental temperatures when planning surveys and analysing observational data.
An hetero-modal deep learning framework for medical image synthesis applied to contrast and non-contrast MRI
Authors: Gourdeau Daniel , Duchesne Simon , Archambault Louis 
Published: August 2024

Abstract
Some pathologies such as cancer and dementia require multiple imaging modalities to fully diagnose and assess the extent of the disease. Magnetic resonance imaging offers this kind of polyvalence, but examinations take time and can require contrast agent injection. The flexible synthesis of these imaging sequences based on the available ones for a given patient could help reduce scan times or circumvent the need for contrast agent injection. In this work, we propose a deep learning architecture that can perform the synthesis of all missing imaging sequences from any subset of available images. The network is trained adversarially, with the generator consisting of parallel 3D U-Net encoders and decoders that optimally combines their multi-resolution representations with a fusion operation learned by an attention network trained conjointly with the generator network. We compare our synthesis performance with 3D networks using other types of fusion and a comparable number of trainable parameters, such as the mean/variance fusion. In all synthesis scenarios except one, the synthesis performance of the network using attention-guided fusion was better than the other fusion schemes. We also inspect the encoded representations and the attention network outputs to gain insights into the synthesis process, and uncover desirable behaviors such as prioritization of specific modalities, flexible construction of the representation when important modalities are missing, and modalities being selected in regions where they carry sequence-specific information. This work suggests that a better construction of the latent representation space in hetero-modal networks can be achieved by using an attention network.
Daemonic quantum battery charged by thermalization
Authors: Satriani Matias Araya , Barra Felipe 
Published: August 2024

Abstract
The reduced state of a small system strongly coupled to a charger in thermal equilibrium may be athermal and used as a small battery once disconnected. By harnessing the battery-charger correlations, the battery’s extractable energy can increase above the ergotropy. We introduce a protocol that uses a quantum system as a memory that measures the charger and leaves the battery intact in its charged state. Using the information gained from the measurement, the daemonic ergotropy of the battery is extracted. Then the battery is reconnected to the charger, thermalizing and charging it. However, the memory should return to its initial standard state to close the thermodynamic cycle. Thus, on the one hand, the work cost of the cycle is the sum of the disconnecting and reconnecting battery-charger work plus the measurement and erasure work. On the other hand, the extracted energy is the daemonic ergotropy of the battery plus the ergotropy of the memory. The ratio of these quantities defines the efficiency of the cycle. The protocol is exemplified by a modified transverse spin 1/2 Ising chain, one spin functioning as the battery and the others as the charger. The memory is another auxiliary spin 1/2. We found pairs of measurement schemes from which we extract the same daemonic ergotropy from the battery, they dissipate the same amount of energy, and one leaves the memory in an active state, the other in a passive state. We study the memory’s ergotropy and the daemonic ergotropy of the battery. We find that with measurements, the efficiency can surpass that of the unmeasured protocol, given conditions on temperature, coupling, and choice of the measurement operators.
Future projections of storm surge in Hurricane Katrina and sensitivity to meteorological forcing resolution
Authors: Danso Derrick K , Patricola Christina M 
Published: August 2024

Abstract
In this study, we investigated whether and how the storm surge induced by Hurricane Katrina could change if it occurs in a future warmer climate, and the sensitivity of the changes to atmospheric forcing resolution. Climate model simulations of Hurricane Katrina at 27 km, 4.5 km, and 3 km resolutions were used to drive storm surge simulations in historical and future climates using the ADvanced CIRCulation (ADCIRC) model. We found that peak surge height increased significantly in the future with all forcing resolutions. However, the future projection is 22% greater in the 3 km forcing, typical of regional climate models, compared to the 27 km forcing, typical of state-of-the-art global climate models. Additionally, the spatial extent of the future change is highly sensitive to forcing resolution, extending most broadly under the 27 km forcing. Furthermore, we found that storm surge duration decreases in the future with all forcing resolutions due to increasing TC translation speed and decreasing ocean lifetime. However, the future change in the surge duration is sensitive to the forcing resolution, decreasing by 31% in the 27 km forcing and 6% in the 3 km forcing.
Heater power supply fluctuations in metal oxide gas sensors: impact on gas sensing performance
Authors: Saidi Tarik , Manser Abderrazak , Welearegay Tesfalem 
Published: August 2024

Abstract
This work reports the impact of deviations in heater current caused by an imprecise 5V power source on the parameters utilized in gas sensing modules in MQ series towards 62 ppm of Ethanol vapor. The gas sensing experiments involved three MQ series gas sensors under lab-made chamber for continuous Ethanol vapor measurement. To investigate how heaters’ current irregularities, affect the gas sensing performance parameters, the sensor’s response/recovery time, pattern recognition techniques of principal component analysis (PCA) and hierarchical cluster analysis (HCA) were employed. While minor voltage drops (±100 mV) may not significantly affect sensing resistance (RS) due to real-time input voltage (Vin) adjustment, a constant current source is essential for heating resistance (RH). The study revealed that a slight increase (±3 mA) in heater supply, particularly from 154 mA (94 °C) to 157 mA (96 °C), can significantly accelerate the recovery time (Trec) of the MQ-7 sensor from 484 s to 316 s, resulting in a difference of over 150 s. This improvement can be attributed to the desorption of gas molecules at higher temperatures, aiding in sensor cleaning. However, this small change does not significantly affect the response time (Tres), which remains between 245 and 295 s at worst. Our gas sensor exhibits enhanced sensitivity and operational stability thanks to a calibrated circuit and stable 5V power supply. Strong correlations between normalized response and sensing films’ temperatures, with a correlation coefficient of 0.985, provide insights into the relationship between heater currents, temperature effects, and gas sensitivity. These findings offer insights for optimizing sensing performance under gas exposure conditions.
Catullus in Twentieth-Century Music
Authors: Oade Stephanie 
Published: August 2024

Abstract
Catullus in Twentieth-Century Music works within the overlap of music and poetry in order to explore the particular lyric voice of Catullus in the context of his twentieth-century musical reception. It considers some of the difficulties inherent in ideas of lyric and lyricism, both specifically in relation to Catullus and more broadly in generic terms. It then uses works of musical reception—settings of Catullus’s poetry from the twentieth century—to clearly identify the essence of Catullan lyricism. Moreover, by considering the very process of reception, it takes a broader view of lyric, identifying traits and characteristics that are common to both music and poetry, thus transcending the boundaries of individual art forms in order to consider the genre in larger, interdisciplinary terms.
Instability in Catullus 3 and Rawsthorne’s Lament for a Sparrow
Authors: Oade Stephanie 
Published: August 2024

Abstract
This chapter continues the study of Catullan reception in song. Through close structural analysis of Catullus poem 3 and Alan Rawsthorne’s song Lament for a Sparrow, developed through a study of voice and tone, the chapter considers both the potential for maintaining lyric traits (such as communality and subjectivity) during the process of reception and the opportunities for appropriation, (re-)interpretation, mediation, dialogism, and generic complication brought about by musical voicing and performance. The chapter also develops the concept of das Gleitende by considering the incremental changes that occur within Catullus’s original text, as well as the ways in which Rawsthorne heightens the effect of these changes in his music.
MetDecode: methylation-based deconvolution of cell-free DNA for noninvasive multi-cancer typing
Authors: Passemiers Antoine , Tuveri Stefania , Sudhakaran Dhanya , Jatsenko Tatjana , Laga Tina , Punie Kevin , Hatse Sigrid , Tejpar Sabine , Coosemans An , Van Nieuwenhuysen Els , Timmerman Dirk , Floris Giuseppe , Van Rompuy Anne-Sophie , Sagaert Xavier , Testa Antonia , Ficherova Daniela , Raimondi Daniele , Amant Frederic , Lenaerts Liesbeth , Moreau Yves , Vermeesch Joris R 
Published: August 2024

Abstract

Motivation
Circulating-cell free DNA (cfDNA) is widely explored as a noninvasive biomarker for cancer screening and diagnosis. The ability to decode the cells of origin in cfDNA would provide biological insights into pathophysiological mechanisms, aiding in cancer characterization and directing clinical management and follow-up.

Results
We developed a DNA methylation signature-based deconvolution algorithm, MetDecode, for cancer tissue origin identification. We built a reference atlas exploiting de novo and published whole-genome methylation sequencing data for colorectal, breast, ovarian, and cervical cancer, and blood-cell-derived entities. MetDecode models the contributors absent in the atlas with methylation patterns learnt on-the-fly from the input cfDNA methylation profiles. In addition, our model accounts for the coverage of each marker region to alleviate potential sources of noise. In-silico experiments showed a limit of detection down to 2.88% of tumor tissue contribution in cfDNA. MetDecode produced Pearson correlation coefficients above 0.95 and outperformed other methods in simulations (P &lt; 0.001; T-test; one-sided). In plasma cfDNA profiles from cancer patients, MetDecode assigned the correct tissue-of-origin in 84.2% of cases. In conclusion, MetDecode can unravel alterations in the cfDNA pool components by accurately estimating the contribution of multiple tissues, while supplied with an imperfect reference atlas.

Availability and implementation
MetDecode is available at https://github.com/JorisVermeeschLab/MetDecode.
Global synthesis indicates widespread occurrence of shifting baseline syndrome
Authors: Soga Masashi , Gaston Kevin J 
Published: August 2024

Abstract
As environmental degradation continues at local, regional, and global levels, people's accepted norms for natural environmental conditions are likely to decline. This phenomenon, known as shifting baseline syndrome (SBS), is increasingly recognized as a likely major obstacle to addressing global environmental challenges. However, the prevalence of SBS remains uncertain. We conducted an extensive systematic review, synthesizing existing research on people's perceived environmental baselines. Our analysis, based on 73 case studies, suggests that SBS is a widespread global phenomenon, occurring across diverse socioeconomic, environmental, and cultural settings. We observed that younger individuals tend to hold lower environmental baselines across various environmental contexts, including climate change, natural resource depletion, biodiversity loss, and pollution. An upward shift in perceived environmental baselines among younger generations was rarely observed. These results underscore the challenge that SBS poses when policy and management responses to environmental degradation are influenced by perceived natural environmental norms.
Outcome analysis of the surgical team in open surgical repair of intact abdominal aortic aneurysm surgery
Authors: Piffaretti Gabriele , Zammito Alessandro , Guzzetti Luca , Selmo Gabriele , Binda Simone , D’Onofrio Dunia , Tozzi Matteo , Franchin Marco 
Published: August 2024

Abstract

OBJECTIVES
To analyze how the experience of the surgical team went to impact the outcomes after open surgical repair (OSR) of intact abdominal aortic aneurysms (AAAs).

METHODS
This is a single-center, observational cohort study with retrospective analysis of all OR for intact AAA performed between 1 January 2010 and 31 December 2022. The primary outcome was survival at 30 days and in follow-up, and a composite outcome of mortality and major complication. The secondary outcome was freedom from aorta-related reintervention. All outcomes were stratified according to the experience of the operating team (surgeons and anesthesiology).

RESULTS
We analyzed 103 (7.2%) patients: 97 (94.2%) males and 6 (5.8%) females. The mean age was 76 ± 8 years (range, 55–93). The best possible team composition was present in 52 (50.5%) interventions. The follow-up index was 0.82 ± 0.18 (range, 0.6–1.0). Mean follow-up duration was 59 ± 43 months (range, 0–158). We observed no differences between teams in major complications (best, 17.3% vs mixed, 21.6%; OR: 0.4, P = 0.622), 30 days mortality (best, 0% vs mixed, 5.9%; OR: 7.6, P = 0.118) and composite outcome (best, 11.5% vs mixed, 17.6%; OR: 0.8, P = 0.416). Cox regression analysis identified the best possible team as a protective factor against the need for reintervention (hazard ratio: 0.2; 95% confidence interval: 0.06–0.88, P = 0.032).

CONCLUSIONS
In our experience, OR of AAA yielded satisfactory results in terms of safety and efficacy independently of the team’s experience. A more experienced team may protect against aorta-related reintervention.