bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Impact of Media Reports on the 2008 Outbreak of Hydrogen Sulfide Suicides in Japan
Authors: Nakamura Mitsuhiro , Yasunaga Hideo , Toda Alexis Akira , Sugihara Toru , Imamura Tomoaki 
Published: December 2012

Objective: Japan experienced a nationwide outbreak of hydrogen sulfide suicides (HSS) between April and May 2008. The annual number of HSS skyrocketed from 19 in 2007 to 1,056 in 2008. However, the factors affecting this enormous increase remain unknown. The present study aimed to examine the effect of media coverage of the incidents on the subsequent epidemic of HSS. Method: We collected time series data from the 1st week of February to the last week of September 2008 (34 weeks), including the number of HSS (St), the number of articles on HSS published in the five major newspapers (Nt), and the number of Internet searches with the keyword “hydrogen sulfide suicide” (Gt). The generalized method of moments was applied to model the concurrent effects of Nt and Gt on St. Results: The increase in the number of newspaper articles significantly induced the increase in HSS (coefficient, 0.84; 95% confidence interval (CI), 0.28–5.3), while the number of Internet searches did not significantly affect the number of HSS (coefficient, −0.75; 95%CI, −19.3–0.45). Conclusions: Exposure to information on HSS from newspaper articles could have directly affected the subsequent increase in the number of suicides. On the other hand, the number of the Internet searches did not have a direct influence on HSS.
The Use of Clonidine in the Treatment of Nightmares among Patients with Co-Morbid PTSD and Traumatic Brain Injury
Authors: Alao Adekola , Selvarajah Jennifer , Razi Syed 
Published: December 2012

Objective: To describe the successful treatment of PTSD associated nightmares in two patients with PTSD. Case Summaries: The report of the successful use of clonidine to treat PTSD associated nightmares among two Veterans following combat exposure. Discussion: Clonidine, a centrally acting alpha-agonist agent used to treat hypertension, stimulates alpha-adrenoreceptors in the brain stem. This action results in reduced sympathetic outflow from the central nervous system. We hypothesize that this central mechanism of action is why clonidine may be more effective in treating nightmares among patients with PTSD when compared with other agents. Conclusion: Clonidine should be considered as an alternative in the treatment of nightmares among patients with PTSD.
Body Mass Index of Inpatients with Schizophrenia in Japan
Authors: Inamura Yukiko , Sagae Toyoaki , Nakamachi Kenichi , Murayama Nobuko 
Published: December 2012

Objective: Many studies reported that obesity rate in the Western countries is higher in schizophrenia patients than in general population. In this study, we surveyed nationwide Body Mass Index (BMI) status of hospitalized Japanese schizophrenia patients. Methods: Subjects included 15,171 patients (7,897 men and 7,274 women) hospitalized for schizophrenia, who were sampled from all 47 administrative divisions in Japan. The BMI data of these patients were compared to those of the general population in the 2009 National Health and Nutrition Survey conducted by the Japanese Ministry of Health. Results: The median BMI value in the patients was 21.6 kg/m2 (first quartile, 19.1; third quartile, 24.5). The percentages of BMI in obese, normal-weight, and underweight patients were 21.6%, 58.2%, and 20.2%, respectively. In the Japanese male patients, frequency of obesity was lower, and underweight was higher than those in the general population. In female patients, frequency of both obesity and underweight were higher than those in the general population. Conclusions: Our results provided evidence that underweight as well as obesity is a characteristic in Japanese schizophrenia inpatients.
How Can Accounting Researchers Become More Innovative?
Authors: Basu Sudipta 
Published: December 2012

SYNOPSIS:
This essay is based on a presentation at the American Accounting Association Strategy Retreat in May 2011 on the assertion “Accounting research as of 2011 is stagnant and lacking in significant innovation that introduces fresh ideas and insights into our scholarly discipline.” It poses the question “How can accounting researchers become more innovative?” and discusses why accounting researchers may have become less innovative. It also outlines some changes in incentive structures and editorial processes needed to achieve greater innovation in accounting research.
JEL Classifications: A11; A12; B23; C12; I23; J44; M4; O31.
Accounting Craftspeople versus Accounting Seers: Exploring the Relevance and Innovation Gaps in Academic Accounting Research
Authors: McCarthy William E. 
Published: December 2012

SYNOPSIS:
Is accounting research stuck in a rut of repetitiveness and irrelevancy? I would answer yes, and I would even predict that both its gap in relevancy and its gap in innovation are going to continue to get worse if the people and the attitudes that govern inquiry in the American academy remain the same. From my perspective in accounting information systems, mainstream accounting research topics have changed very little in 30 years, except for the fact that their scope now seems much more narrow and crowded. More and more people seem to be studying the same topics in financial reporting and managerial control in the same ways, over and over and over. My suggestions to get out of this rut are simple. First, the profession should allow itself to think a little bit normatively, so we can actually target practice improvement as a real goal. And second, we need to allow new scholars a wider berth in research topics and methods, so we can actually give the kind of creativity and innovation that occurs naturally with young people a chance to blossom.
Early Warnings of Internal Control Problems: Additional Evidence
Authors: Munsif Vishal , Raghunandan K. , Rama Dasaratha V. 
Published: December 2012

SUMMARY:
Hermanson and Ye (2009; hereafter, HY) find that in the initial year of SOX Section 404 implementation, only 27 percent of accelerated filer firms with an adverse Section 404(b) report had disclosed such material weaknesses (MWs) in internal control in Section 302 certifications in previous quarters of the same fiscal year. We extend HY by examining (1) a more recent time period (using data from fiscal years 2007 and 2008), and (2) both accelerated and non-accelerated filers. We find that the proportion of accelerated filers (with adverse Section 404 reports) that have early warnings (in Section 302 certifications in previous quarters of the same fiscal year) is less than 50 percent even in the fourth and fifth years of Section 404 reporting. We also find that, after controlling for other factors, non-accelerated filers were more likely to have early warnings than accelerated filers in 2008; however, the difference is not significant in 2007. Early warning is more likely for firms with (1) a higher number of MWs, (2) a new CFO, (3) more audit committee members, and (4) more frequent audit committee meetings.
Assessment of owner willingness to treat or manage diseases of dogs and cats as a guide to shelter animal adoptability
Authors: Murphy Molly D. , Larson Janice , Tyler Allison , Kvam Vanessa , Frank Kristen , Eia Cheryl , Bickett-Weddle Danelle , Flaming Kevan , Baldwin Claudia J. , Petersen Christine A. 
Published: December 2012

Abstract
Objective—To determine community approaches to medical and behavioral diseases in dogs and cats.
Design—Cross-sectional descriptive study.
Sample—97 companion animal veterinarians and 424 animal owners.
Procedures—Companion animal veterinarians in central Iowa ranked medical or behavioral diseases or conditions by what they thought most clients would consider healthy, treatable, manageable, or unhealthy (unmanageable or untreatable). In a parallel survey, cat- or dog-owning households in central Iowa responded to a telephone survey regarding the relationship of their animal in the household, owner willingness to provide medical or behavioral interventions, and extent of financial commitment to resolving diseases.
Results—One hundred twenty common health or behavioral disorders in cats and dogs were ranked by veterinarians as healthy, treatable, manageable, or unhealthy (unmanageable or untreatable) on the basis of their opinion of what most clients would do. Findings were in congruence with animal owners' expressed willingness to provide the type of care required to maintain animals with many acute or chronic medical and behavioral conditions. In general, owners indicated a willingness to use various treatment modalities and spend money on veterinary services when considering current or previously owned animals as well as hypothetical situations with an animal. Past experiences with veterinary care in which an animal did not recover fully did not diminish the willingness of respondents to use veterinary services again in the future.
Conclusions and Clinical Relevance—These results provide a baseline indication of community willingness to address medical or behavioral conditions in dogs and cats. These considerations can be used in conjunction with Asilomar Accords recommendations to assess adoptability of cats and dogs in animal shelters.
Evaluation of plasma lactate concentration and base excess at the time of hospital admission as predictors of gastric necrosis and outcome and correlation between those variables in dogs with gastric dilatation-volvulus: 78 cases (2004–2009)
Authors: Santoro Beer Kari A. , Syring Rebecca S. , Drobatz Kenneth J. 
Published: December 2012

Abstract
Objective—To determine the correlation between plasma lactate concentration and base excess at the time of hospital admission and evaluate each variable as a predictor of gastric necrosis or outcome in dogs with gastric dilatation-volvulus (GDV).
Design—Retrospective case series.
Animals—78 dogs.
Procedures—For each dog, various data, including plasma lactate concentration and base excess at the time of hospital admission, surgical or necropsy findings, and outcome, were collected from medical records.
Results—Gastric necrosis was identified in 12 dogs at the time of surgery and in 4 dogs at necropsy. Sixty-five (83%) dogs survived to hospital discharge, whereas 13 (17%) dogs died or were euthanized. Of the 65 survivors and 8 nonsurvivors that underwent surgery, gastric necrosis was detected in 8 and 4 dogs, respectively. Via receiver operating characteristic curve analysis, an initial plasma lactate concentration cutoff of 7.4 mmol/L was 82% accurate for predicting gastric necrosis (sensitivity, 50%; specificity, 88%) and 88% accurate for predicting outcome (sensitivity, 75%; specificity, 89%). Among all dogs, the correlation between initial plasma lactate concentration and base excess was significant, although base excess was a poor discriminator for predicting gastric necrosis or outcome (area under the receiver operating characteristic curve, 0.571 and 0.565, respectively).
Conclusions and Clinical Relevance—In dogs with GDV, plasma lactate concentration at the time of hospital admission was a good predictor of gastric necrosis and outcome. However, despite the correlation between initial base excess and plasma lactate concentration, base excess should not be used for prediction of gastric necrosis or outcome in those patients.
Computed tomographic findings in dogs and cats with temporomandibular joint disorders: 58 cases (2006–2011)
Authors: Arzi Boaz , Cissell Derek D. , Verstraete Frank J. M. , Kass Philip H. , DuRaine Grayson D. , Athanasiou Kyriacos A. 
Published: December 2012

Abstract
Objective—To describe CT findings in dogs and cats with temporomandibular joint (TMJ) disorders.
Design—Retrospective case series.
Animals—41 dogs and 17 cats.
Procedures—Medical records and CT images of the skull were reviewed for dogs and cats that were examined at a dentistry and oral surgery specialty practice between 2006 and 2011.
Results—Of 142 dogs and 42 cats evaluated, 41 dogs and 17 cats had CT findings consistent with a TMJ disorder. In dogs, the most common TMJ disorder was osteoarthritis; however, in most cases, there were other TMJ disorders present in addition to osteoarthritis. Osteoarthritis was more frequently identified at the medial aspect rather than the lateral aspect of the TMJ, whereas the frequency of osteoarthritic involvement of the dorsal and ventral compartments did not differ significantly. In cats, fractures were the most common TMJ disorder, followed by osteoarthritis. Clinical signs were observed in all dogs and cats with TMJ fractures, dysplasia, ankylosis, luxation, and tumors; however, only 4 of 15 dogs and 2 of 4 cats with osteoarthritis alone had clinical signs.
Conclusions and Clinical Relevance—Results indicated that TMJ disorders were frequently present in combination. Osteoarthritis was the most common TMJ disorder in dogs and the second most common TMJ disorder in cats. Computed tomography should be considered as a tool for the diagnosis of TMJ disorders in dogs and cats with suspected orofacial disorders and signs of pain. (J Am Vet Med Assoc 2013;242:69–75)
A Task-based Support Architecture for Developing Point-of-care Clinical Decision Support Systems for the Emergency Department
Authors: Michalowski W. , O’Sullivan D. , Farion K. , Sayyad-Shirabad J. , Kuziemsky C. , Kukawka B. , Wilk S. 
Published: December 2012

SummaryObjectives: The purpose of this study was to create a task-based support architecture for developing clinical decision support systems (CDSSs) that assist physicians in making decisions at the point-of-care in the emergency department (ED). The backbone of the proposed architecture was established by a task-based emergency workflow model for a patient-physician encounter.Methods: The architecture was designed according to an agent-oriented paradigm. Specifically, we used the O-MaSE (Organization-based Multi-agent System Engineering) method that allows for iterative translation of functional requirements into architectural components (e.g., agents). The agent-oriented paradigm was extended with ontology-driven design to implement ontological models representing knowledge required by specific agents to operate.Results: The task-based architecture allows for the creation of a CDSS that is aligned with the task-based emergency workflow model. It facilitates decoupling of executable components (agents) from embedded domain knowledge (ontological models), thus supporting their interoperability, sharing, and reuse. The generic architecture was implemented as a pilot system, MET3-AE – a CDSS to help with the management of pediatric asthma exacerbation in the ED. The system was evaluated in a hospital ED.Conclusions: The architecture allows for the creation of a CDSS that integrates support for all tasks from the task-based emergency workflow model, and interacts with hospital information systems. Proposed architecture also allows for reusing and sharing system components and knowledge across disease-specific CDSSs.
Patient Preferences for Hepatitis B Therapy
Authors: Lim Seng Gee , Aung Myat Oo , Chung Stephanie WM , Soon Charlene SL , Mak Belinda HN , Lee Keat Hong 
Published: December 2012

Background Little is known about patient preferences for selection of chronic hepatitis B (CHB) treatment. This issue is important as it affects the therapeutic choices available for patients and, in the long term, the health of CHB patients. Methods The study was a questionnaire-led survey directed at patients attending a CHB follow-up clinic. Patients were asked questions regarding their knowledge on CHB treatment, preferred route and frequency of administration, duration of treatment, cost, adverse events, viral resistance, efficacy and whether treatment options were discussed with doctors. Patients were also asked to rank their priorities when selecting treatment for CHB. In addition, a summary of the profile of current agents was shown to patients who were then asked to select their preferred therapy. Finally, patients were asked questions regarding their willingness to pay for CHB treatment and expectations of treatment. Questionnaires were self-administered and statistical analysis was performed using SPSS (version 10.0). Results Lamivudine was the best-known drug among patients. Only 30% of patients were treatment-naive. Most patients preferred oral therapy with once-daily dosing and a fixed duration of treatment. Drug efficacy was considered the most important factor in drug selection. When shown the profile of the different drugs available for the treatment of CHB, entecavir was the preferred choice of therapy. The majority of patients were willing to spend no more than S$10 (USD 8) daily for therapy with expectation of cure for their disease. Overall, 92% of patients would follow doctor's recommendations. Conclusions Patients’ preferences are important in evaluating drug selection for CHB.
Plasma Concentrations of Efavirenz with a 600 Mg Standard Dose in Cambodian HIV-Infected Adults Treated for Tuberculosis with a Body Weight above 50 Kg
Authors: Borand Laurence , Laureillard Didier , Madec Yoann , Chou Monidarin , Pheng Phearavin , Marcy Olivier , Sok Thim , Goldfeld Anne E , Taburet Anne-Marie , Blanc François-Xavier ,   the CAMELIA (ANRS 1295-CIPRA KH001) study team
Published: December 2012

Background The optimal dose of efavirenz for HIV-infected patients receiving a tuberculosis regimen including rifampicin remains debated, especially for subjects weighing over 50 kg. To address this issue, we measured plasma efavirenz concentrations from Cambodian adults with tuberculosis enrolled in the CAMELIA randomized trial (ClinicalTrials.gov number, NCT01300481) 6 weeks after the onset of antiretroviral therapy. Methods Efavirenz concentrations and proportions of patients with concentrations below 1,000 ng/ml were compared across patient body weight below or above 50 kg using a Student's t-test and a c2 test, respectively. Factors associated with efavirenz concentrations below 1,000 ng/ml were identified by logistic regression analysis. Logistic regression analysis was also performed to check if efavirenz concentrations below 1,000 ng/ml were associated with virological failure. Results Plasma efavirenz concentrations were higher in the 332 patients who weighed <50 kg compared with the 150 who weighed ≥50 kg (median [IQR] 2,859 [1,787–4,749] and 2,060 [1,425–3,575] ng/ml, respectively; P=0.02). However, the proportion of patients with efavirenz concentrations below 1,000 ng/ml was not different between those weighing less than or more than 50 kg (6% and 10%, respectively; P=0.13) and a body weight above 50 kg was not associated with a higher risk of plasma efavirenz concentrations below 1,000 ng/ml. When plasma efavirenz concentrations below 1,000 ng/ml were present, they were not associated with virological failure. Conclusions The current WHO guidelines recommending 600 mg efavirenz daily irrespective of patient's body weight remains a safe and effective approach to treating coinfected adults needing simultaneous tuberculosis and HIV therapy.
Un regard rétrospectif sur un demi-siècle d'enquêtes empiriques dans la sociologie française
Authors: Chapoulie Jean-Michel 
Published: December 2012

Résumé Comment les recherches universitaires en sociologie, au sens large, sur le monde contemporain ont-elles évolué en France depuis les années 1960 ? L’auteur examine les enquêtes, démarches de recherche, cadres intellectuels et financiers où elles sont réalisées et interprétées, leurs relations avec les commanditaires, les débats publics et le réseau international. Partant de sources variées et étendues –comptes rendus de recherches, monographies, témoignages, rapports, archives du CNRS, documents financiers, etc.– l’article distingue deux périodes, 1960-1980 (poids de l’exploitation statistique des enquêtes) et 1980-2010 (diversification et empirie), et suggère, sans jugement de valeur, trois évolutions majeures : –le processus ininterrompu depuis le début des années 1960 de diversification des sujets et des démarches, accompagné d’une insertion progressive dans un environnement international, notamment anglo-saxon puis européen ; –l’introduction au cours des vingt dernières années de deux variables : le genre et l’appartenance ethnique (peu stable car historiquement construite dans chaque situation nationale) ; –enfin, le cadre sociogéographique d’interprétation des analyses devenu plus incertain au fil des ans. Le recul temporel montre la relation entre ces évolutions, les financements, les problèmes sociaux publics et le renouvellement des domaines et sujets d’enquête où une variable essentielle, les relations de classe, rarement ignorée dans les années 1960-1970 paraît oubliée aujourd’hui.
Aller au bout de la critique du mythe du donné : McDowell avec et contre Sellars
Authors: Le Goff Alice 
Published: December 2012

Résumé Le dépassement du mythe du donné est au fondement de la conception mcdowellienne de la connaissance et de la pensée. En cela, McDowell prolonge l’analyse de Sellars. Il s’oppose cependant à la recherche, par ce dernier, d’une « pure sensation » comme élément causal de la connaissance. Celle-ci ne serait qu’un nouvel avatar du donné et tombe, d’après McDowell, sous le coup de la propre réfutation sellarsienne du mythe. Mais il reste possible de concevoir un donné déjà conceptuel. C’est ainsi que peut être dépassé le mythe et c’est, d’après McDowell, ce que Kant, nonobstant les critiques que lui adresse Sellars, permet de penser. Toutefois, McDowell lui-même ne tombe-t-il pas dans une autre version du mythe du donné, à propos de ce que Sellars appelle le donné catégorial ? Nous montrerons que cette accusation, élevée notamment par Rosenberg, méconnaît le sens du donné conceptuel proposé par McDowell.
Mythe du donné, mythe de la pensée
Authors: Benoist Jocelyn 
Published: December 2012

Résumé L’article met en évidence comment le mythe du donné est le produit de l’épistémologie moderne, reposant sur la séparation de l’esprit et du monde et une conception abstraite de la pensée. Ainsi, il insiste sur le fait qu’un tel mythe, sous son apparence dogmatique, est lié à l’attitude transcendantale. Pour que les choses aient à être données, nous devons faire comme si nous ne les avions pas déjà. Dès lors, le contact avec elles a à être établi. En un second temps, l’article montre comment une certaine façon de critiquer le mythe du donné n’est que l’autre face du même mythe : dire que les choses ne peuvent pas être juste données, mais doivent être pensées signifie une fois encore qu’on ignore qu’on ne peut les penser que dans la mesure où on les a déjà. Appréhender la véritable connexion de la pensée et de la réalité, c’est surmonter et le mythe du donné et celui de la pensée en tant que conditions transcendantales du contact.