bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Impact of a Diabetes Self-Management Education Program Provided through a Telemedicine Link to Rural California Health Care Clinics
Authors: Nuovo Jim 
Published: January 2013

Background This project investigated the impact of a DM self-management education program provided through a telemedicine link at nine rural health clinics in Northern California. Methods Two hundred thirty nine patients were provided with a single 2-hour class on DM delivered through a live televideo connection. Patients provided pre-intervention information on: demographics and overall health, self-care behaviors, and knowledge about DM. All participants completed a post-education survey on knowledge and self-care behaviors. Results There was a significant decrease in the number of patients who felt overwhelmed with their DM; pre-intervention 18.8%; post-intervention 5.4% ( P < 0.0001). Patients increased the number of days they exercised; pre-intervention 3.4 days; post-intervention 3.9 days ( P = 0.02). Patients increased the number of days they checked their feet; pre-intervention 4.2 days; post-intervention 5.6 days ( P < 0.01). Knowledge about DM improved over the study period ( P < 0.01). Conclusions A single 2-hour class on DM administered through a telemedicine link to patients in rural health clinics resulted in feeling less overwhelmed, more knowledgeable about DM, and demonstrated an increase in self-care behavior; ie, exercise and foot care.
Transient stability analysis with equal-area criterion for out of step detection using phasor measurement units
Authors: Abdelaziz A.Y. , Ibrahim Amr M. , Hasan Zeinab G. 
Published: January 2013

The electrical power systems function as a huge interconnected network dispersed over a large area. A balance exist between generated and consumed power, any disturbance to this balance in the system caused due to change in load as well as faults and their clearance often results in electromechanical oscillations. As a result there is variation in power flow between two areas. This phenomenon is referred as Power Swing. This paper presents a transmission line protection scheme that uses measured values of the currents and voltages of the three phases of two buses (equivalent to PMU data). The measured data is transformed from time domain into phasor domain using Discrete Fourier Transform to predict whether the swing is a stable or an unstable one. The performance of the method has been tested on a simulated system using PSCAD and MATLAB software. The proposed scheme can be used for the detection of out of step condition using equal-area criterion with different types of faults at different locations and different models of transmission lines.Keywords: Phasor Measurement Unit, Global positioning system, Transmission line protection, Power system transient stability, Discrete Fourier Transform, Equal-Area Criterion, Out of step detection
A Novel Method to Radiolabel Stealth Liposome through 1,2- dimyristoyl-sn-glycero-3-phosphoethanolamine-N-DTPA with 99mTc and Biological Evaluation
Authors: Mirel Cabrera  , Alejandra Medrano  , Nicole Lecot  , Marcelo Fernandez  , Maria Moreno  , Jose A Chabalgoity  , Juan Pablo Gambini  , Omar Alonso  , Henia Balter  , Pablo Cabral  
Published: January 2013

Purpose: To study surface technetium labeling of stealth DTPA-Liposomeand to evaluate its potential as a molecular imaging tracer for both normal and melanoma-bearing mice. The radiolabeling yield of liposomes was greater than 90%and showed good chemical and biological stability. Biodistribution studies in normal mice showed blood clearance with hepatic and renal depuration. Melanoma-bearing mice showed a similar pattern of biodistribution with high tumor uptake allowing tumor imaging. The developed method of surface radiolabeled DTPA-PEG-Liposomes with 99mTc was effective and stable in vivo.
Saint-Denys Garneau : le jeu de l’ironie
Authors: Mainguy Thomas 
Published: January 2013

Suivant l’image de la révolution copernicienne, le présent article traite de l’ironie dans les poèmes garnéliens. Il s’agira d’abord d’évaluer le « rêve poétique » de Garneau pour comprendre l’impact de cette révolution. Selon l’allégorie formulée dans « Le jeu », la poésie constitue un espace de liberté où l’imagination ordonne et invente le monde à sa guise. On sent poindre le sentiment d’une grâce qu’on retrouvera aussi dans les « Esquisses en plein air ». On ne peut toutefois pas s’en tenir à cette seule lecture. Le principe même de l’allégorie met ici en lumière la proximité foncière de l’ironie et de la poésie, chacune faisant place à une « parole oblique », pour reprendre l’expression de Philippe Hamon. Inscrite, pourrait-on dire, dans le code génétique de la poésie garnélienne, l’ironie est à la source de la révolution copernicienne que la deuxième partie de l’article analysera. En effet, le poème « Autrefois » relate une rupture sur le plan de la conscience poétique ; rupture illustrée notamment par l’usage discordant d’un vocabulaire scientifique. L’ironie intervient ainsi à la faveur d’un retournement critique qui dissipe les illusions provoquées par les premiers enthousiasmes poétiques, dont celle de la centralité du sujet dans le monde. Destinée à devenir un exercice de subtilité, la poésie en mode ironique refuse les excès du lyrisme, qu’ils soient euphoriques ou désespérés, mais cherche l’« équilibre impondérable » qui rallie les contraires : la gravité, le rire ; l’identité, l’altérité ; la poésie, la prose ; l’intelligible, le sensible ; l’apprentissage, le désapprentissage.
Einfach‐, Doppel‐, Dreifachbindungen und Ketten: Knüpfung elektronenpräziser B‐B‐Bindungen
Authors: Braunschweig Holger , Dewhurst Rian D. 
Published: January 2013

AbstractTrotz des großen präparativen Interesses an Diboranen und der hohen B‐B‐Bindungsenthalpie ist die Knüpfung von Bor‐Bor‐Bindungen immer noch schwierig, kaum zu kontrollieren und schlecht vorhersagbar. Methoden zur Herstellung von B‐B‐Mehrfachbindungen sind sogar noch seltener. In den letzten Jahren gab es nun einige Fortschritte zur Lösung dieser Probleme, und dieser Kurzaufsatz unternimmt den Versuch, einen Überblick über die Geschichte der B‐B‐Bindungsbildung zu geben und neue Ergebnisse auf diesem Gebiet zusammenzufassen.
Synthesis and catalytic activity of the thermoresponsive polymers having pyrrolidine side chains as base functionalities
Authors: Uemukai Toru , Ishifune Manabu 
Published: January 2013

AbstractOptically active polymers having chiral 2‐aminomethylpyrrolidine side chains have been newly synthesized by a radical homopolymerization of the corresponding protected acrylamide monomer and copolymerization with N‐isopropylacrylamide followed by deprotection. The resulting polymers were found to be thermoresponsive showing lower critical solution temperatures (LCSTs) at 27–65°C in their aqueous solutions. The pyrrolidine side chains of the resulting thermoresponsive polymer promoted aldol reaction between cyclohexanone and p‐nitrobenzaldehyde in water, and the reaction proceeded most smoothly at its LCST. Moreover, the diastereomeric ratio (syn : anti) of the aldol adducts obtained at the reaction at 40°C was 22 : 78, whereas the diastereomeric ratio (syn : anti) was 55 : 45 at 20°C. These results indicate that the pyrrolidine side chains catalyze the aldol reactions in the relatively hydrophobic field generated by the thermoresponsive polymer at its LCST. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013
Improvement of gas barrier property of polyolefins by diamond‐like carbon deposition and photografting polymerization
Authors: Takahashi Jun , Nakaya Masaki , Matsui Eitaro , Hotta Atsushi 
Published: January 2013

AbstractThe gas barrier properties of isotactic polypropylene (iPP) and high‐density polyethylene (HDPE) are both significantly improved by diamond‐like carbon (DLC) deposition and photografting polymerization using acrylic acid (AA) monomers. In fact, the gas barrier properties can be highly improved just by DLC or by AA‐photografting polymerization. The improvement observed by AA‐photografting polymerization is more pronounced than that by DLC deposition in our general experimental condition. In more detail, the oxygen barrier property of DLC‐deposited and AA‐grafted iPP is considerably improved by ∼10 times when compared with that of neat iPP. As for HDPE, the oxygen barrier property is enhanced by nearly six times through DLC deposition and photografting polymerization. By observing the surfaces, 30 nm layer of DLC and 1.0 μm of AA‐grafted layer are firmly constructed on the polyolefins, which should contribute to the enhancement of the oxygen barrier property. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013
The effect of devulcanization level on mechanical properties of reclaimed rubber by thermal‐mechanical shearing devulcanization
Authors: Tao Guoliang , He Qianhu , Xia Yanping , Jia Guangcheng , Yang Haicun , Ma Wenzhong 
Published: January 2013

AbstractGround tire rubber (GTR) with crosslinked structure has hardly any plasticity and processability, which makes its property very poor. Thermal‐mechanical shearing devulcanization method can effectively destroy the crosslinked structure and restore GTR a certain extent of plasticity and processability. This article investigated the characteristic and reprocessing performance of reclaimed rubber prepared through thermal‐mechanical shearing devulcanization. The relationship between the devulcanization level (indicated by gel fraction and crosslink density) and the mechanical property was analyzed by sufficient experiments. Fourier transform infrared spectroscopy and elemental analyzer studies revealed the chemical structure of GTR changed and many complex reactions occurred after devulcanization. The gel permeation chromatography indicated the specific changes of molecular weight and molecular weight distribution in devulcanization process. The differential scanning calorimetry revealed various vulcanized abilities and vulcanized structures of reclaimed rubber. The scanning electron microscope further confirmed the recovery of plasticity after devulcanization and the distinct vulcanized structures between revulcanizates. The determination of devulcanization level and mechanical properties verified that mechanical properties especially tensile strength reached to the optimum value only at an appropriate devulcanization level. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013
Single nucleotide polymorphisms found in the red alga Furcellaria lumbricalis (Gigartinales): new markers for population and conservation genetic analyses
Authors: Olsson Sanna , Korpelainen Helena 
Published: January 2013

ABSTRACTExpressed sequence tag (EST) libraries were generated from two populations of the red alga Furcellaria lumbricalis (Hudson) Lamouroux originating from different environmental conditions (the Atlantic Ocean and the brackish Baltic Sea), compared with each other and used to guide the design of single nucleotide polymorphism (SNP) markers. The species is endemic to the northern Atlantic, while in the low‐salinity conditions of the Baltic Sea it occurs at the margin of its distribution and is presently threatened by eutrophication.Primers were developed for 13 transcribed regions, five of which were found to be variable at population level, containing a total of 20 SNP sites, which were then utilized in population genetic analyses on F. lumbricalis originating from different geographical locations and salinity conditions in northern and western Europe, and the results were compared with previous data of putatively neutral and adaptive (EST‐derived) microsatellites.Although no conclusive evidence of selection was detected in neutrality tests, the level of genetic differentiation based on SNP variation (FST = 0.522; but 0.398 and 0.095 for EST‐derived and putatively neutral microsatellites, respectively) is so great that the role of selection is evident. The Bayesian structure analysis supported the view of great differentiation between marine and brackish populations.Although the new primers were designed for F. lumbricalis, the same gene regions may have utility in population genetic and phylogenetic studies across red algal species. Copyright © 2013 John Wiley & Sons, Ltd.
Ligand Functionalization and Its Effect on CO2 Adsorption in Microporous Metal–Organic Frameworks
Authors: Liu Hui , Zhao Yonggang , Zhang Zhijuan , Nijem Nour , Chabal Yves J. , Peng Xiangfang , Zeng Heping , Li Jing 
Published: January 2013

AbstractWe report two new 3D structures, [Zn3(bpdc)3(2,2′‐dmbpy)] (DMF)x(H2O)y (1) and [Zn3(bpdc)3(3,3′‐dmbpy)]⋅(DMF)4(H2O)0.5 (2), by methyl functionalization of the pillar ligand in [Zn3(bpdc)3(bpy)] (DMF)4⋅(H2O) (3) (bpdc=biphenyl‐4,4′‐dicarboxylic acid; z,z′‐dmbpy=z,z′‐dimethyl‐4,4′‐bipyridine; bpy=4,4′‐bipyridine). Single‐crystal X‐ray diffraction analysis indicates that 2 is isostructural to 3, and the power X‐ray diffraction (PXRD) study shows a very similar framework of 1 to 2 and 3. Both 1 and 2 are 3D porous structures made of Zn3(COO)6 secondary building units (SBUs) and 2,2′‐ or 3,3′‐dmbpy as pillar ligand. Thermogravimetric analysis (TGA) and PXRD studies reveal high thermal and water stability for both compounds. Gas‐adsorption studies show that the reduction of surface area and pore volume by introducing a methyl group to the bpy ligand leads to a decrease in H2 uptake for both compounds. However, CO2 adsorption experiments with 1′ (guest‐free 1) indicate significant enhancement in CO2 uptake, whereas for 2′ (guest‐free 2) the adsorbed amount is decreased. These results suggest that there are two opposing and competitive effects brought on by methyl functionalization: the enhancement due to increased isosteric heats of CO2 adsorption (Qst), and the detraction due to the reduction of surface area and pore volume. For 1′, the enhancement effect dominates, which leads to a significantly higher uptake of CO2 than its parent compound 3′ (guest‐free 3). For 2′, the detraction effect predominates, thereby resulting in reduced CO2 uptake relative to its parent structure 3′. IR and Raman spectroscopic studies also present evidence for strong interaction between CO2 and methyl‐functionalized π moieties. Furthermore, all compounds exhibit high separation capability for CO2 over other small gases including CH4, CO, N2, and O2.
Robust Observer and Observer‐Based Controller for Time‐Delay Singular Systems
Authors: Hassan L. , Zemouche A. , Boutayeb M. 
Published: January 2013

AbstractIn this paper we address the problems of observer and observer‐based controller design for a class of nonlinear time‐delay singular systems. The proposed methods use particular Lyapunov functions depending on the disturbances in order to avoid a specific obstacle in the stability analysis. Consequently, two linear matrix inequality (LMI) conditions ensuring the convergence of the estimation error and the closed loop system were presented. These LMIs were obtained by manipulating Young's inequality in order to linearize some bilinear terms.
RETRACTED: Expression of adrenomedullin in human colorectal tumors and its role in cell growth and invasion in vitro and in xenograft growth in vivo
Authors: Nouguerède Emilie , Berenguer Caroline , Garcia Stéphane , Bennani Bahia , Delfino Christine , Nanni Isabelle , Dahan Laetitia , Gasmi Mohamed , Seitz Jean‐François , Martin Pierre‐Marie , Ouafik L'Houcine 
Published: January 2013

AbstractAdrenomedullin (AM) is a multifunctional peptide vasodilator that transduces its effects through calcitonin receptor‐like receptor/receptor activity‐modifying protein‐2 and ‐3 (CLR/RAMP2 and CLR/RAMP3). In this study, real‐time quantitative reverse transcription demonstrated a significant expression of AM mRNA in tumor samples from colorectal cancer (CRC) patients in clinical stage II, III, and IV when compared with normal colorectal tissue. AM, CLR, RAMP2, and RAMP3 proteins were immunohistochemically localized in the carcinomatous epithelial compartment of CRC tissue. Tissue microarray analysis revealed a clear increase of AM, CLR, RAMP2, and RAMP3 staining in lymph node and distant metastasis when compared with primary tumors. The human colon carcinoma cells HT‐29 expressed and secreted AM into the culture medium with a significant increase under hypoxia. Treatment of HT‐29 cells with synthetic AM stimulated cell proliferation and invasion in vitro. Incubation with anti‐AM antibody (αAM), anti‐AM receptors antibodies (αAMR), or AM antagonist AM22–52 inhibited significantly basal levels of proliferation of HT‐29 cells, suggesting that AM may function as an autocrine growth factor for CRC cells. Treatment with αAM significantly suppressed the growth of HT‐29 tumor xenografts in vivo. Histological examination of αAM‐treated tumors showed evidence of disruption of tumor vascularity with decreased microvessel density, depletion of endothelial cells and pericytes, and increased tumor cell apoptosis. These findings highlight the potential importance of AM and its receptors in the progression of CRC and support the conclusion that αAM treatment inhibits tumor growth by suppression of angiogenesis and tumor growth, suggesting that AM may be a useful therapeutic target.
Selective Production of Aromatics from Alkylfurans over Solid Acid Catalysts
Authors: Wang Dong , Osmundsen Christian M. , Taarning Esben , Dumesic James A. 
Published: January 2013

AbstractSolid acid catalysts were studied at temperatures near 523 K for the production of benzene, toluene, and p‐xylene by the reaction of ethylene with furan, 2‐methylfuran, and 2,5‐dimethylfuran, respectively, through the combination of cycloaddition and dehydrative aromatization reactions. Catalysts containing Brønsted acid and Lewis acid sites (i.e., WOx–ZrO2, niobic acid, zeolite Y, silica–alumina) were more active than catalysts containing predominantly Lewis acid sites (γ‐Al2O3, TiO2), which indicates the importance of Brønsted acidity in the production of aromatics. Microporosity is not required for this reaction, because amorphous solid acids and homogeneous Brønsted acids demonstrate significant activity for p‐xylene production. The production of p‐xylene from 2,5‐dimethylfuran proceeded at higher rates compared with the production of toluene and benzene from 2‐methylfuran and furan, respectively. Both WOx–ZrO2 and niobic acid demonstrate superior activity for aromatics production than does zeolite Y. WOx–ZrO2 demonstrates a turnover frequency for p‐xylene production that is 35 times higher than that demonstrated by zeolite Y. In addition, mesoporous materials such as WOx–ZrO2 offer higher resistance to deactivation by carbon deposition than do microporous materials. Results from Raman spectroscopy and the trend of turnover frequency with varying tungsten surface densities for a series of WOx–ZrO2 catalysts are consistent with previous investigations of other acid‐catalyzed reactions; this suggests that the high reactivity of WOx–ZrO2 is mainly associated with the presence of subnanometer WOx clusters mixed with zirconium, which reach a maximum surface concentration at intermediate tungsten coverage.
Does Hydrogen‐Bonding Donation to Manganese(IV)–Oxo and Iron(IV)–Oxo Oxidants Affect the Oxygen‐Atom Transfer Ability? A Computational Study
Authors: Latifi Reza , Sainna Mala A. , Rybak‐Akimova Elena V. , de Visser Sam P. 
Published: January 2013

AbstractIron(IV)–oxo intermediates are involved in oxidations catalyzed by heme and nonheme iron enzymes, including the cytochromes P450. At the distal site of the heme in P450 Compound I (FeIV–oxo bound to porphyrin radical), the oxo group is involved in several hydrogen‐bonding interactions with the protein, but their role in catalysis is currently unknown. In this work, we investigate the effects of hydrogen bonding on the reactivity of high‐valent metal–oxo moiety in a nonheme iron biomimetic model complex with trigonal bipyramidal symmetry that has three hydrogen‐bond donors directed toward a metal(IV)–oxo group. We show these interactions lower the oxidative power of the oxidant in reactions with dehydroanthracene and cyclohexadiene dramatically as they decrease the strength of the OH bond (BDEOH) in the resulting metal(III)–hydroxo complex. Furthermore, the distal hydrogen‐bonding effects cause stereochemical repulsions with the approaching substrate and force a sideways attack rather than a more favorable attack from the top. The calculations, therefore, give important new insights into distal hydrogen bonding, and show that in biomimetic, and, by extension, enzymatic systems, the hydrogen bond may be important for proton‐relay mechanisms involved in the formation of the metal–oxo intermediates, but the enzyme pays the price for this by reduced hydrogen atom abstraction ability of the intermediate. Indeed, in nonheme iron enzymes, where no proton relay takes place, there generally is no donating hydrogen bond to the iron(IV)–oxo moiety.
Biotransformations of Anticancer Ruthenium(III) Complexes: An X‐Ray Absorption Spectroscopic Study
Authors: Levina Aviva , Aitken Jade B. , Gwee Yee Yen , Lim Zhi Jun , Liu Mimi , Singharay Anannya Mitra , Wong Pok Fai , Lay Peter A. 
Published: January 2013

AbstractAn anti‐metastatic drug, NAMI‐A ((ImH)[RuIIICl4(Im)(dmso)]; Im=imidazole, dmso=S‐bound dimethylsulfoxide), and a cytotoxic drug, KP1019 ((IndH)[RuIIICl4(Ind)2]; Ind=indazole), are two Ru‐based anticancer drugs in human clinical trials. Their reactivities under biologically relevant conditions, including aqueous buffers, protein solutions or gels (e.g, albumin, transferrin and collagen), undiluted blood serum, cell‐culture medium and human liver (HepG2) cancer cells, were studied by Ru K‐edge X‐ray absorption spectroscopy (XAS). These XAS data were fitted from linear combinations of spectra of well‐characterised Ru compounds. The absence of XAS data from the parent drugs in these fits points to profound changes in the coordination environments of RuIII. The fits point to the presence of RuIV/III clusters and binding of RuIII to S‐donor groups, amine/imine and carboxylato groups of proteins. Cellular uptake of KP1019 is approximately 20‐fold higher than that of NAMI‐A under the same conditions, but it diminishes drastically after the decomposition of KP1019 in cell‐culture media, which indicate that the parent complex is taken in by cells through passive diffusion.
Enantiospecific Photochemical Transformations under Elevated Pressure
Authors: Ayitou Anoklase J.‐L. , Fukuhara Gaku , Kumarasamy Elango , Inoue Yoshihisa , Sivaguru J. 
Published: January 2013

AbstractEnantiospecific axial‐to‐point chiral transfer in light‐induced transformations was efficient under elevated pressure at high temperatures. Model photoreactions with atropisomeric compounds showed higher enantioselectivity in the photoproducts under elevated pressure. The ee values in the photoproducts were rationalized based on the increased stability of optically pure atropisomeric compounds at elevated pressure, even at high temperatures.
Highly Emissive Boron Ketoiminate Derivatives as a New Class of Aggregation‐Induced Emission Fluorophores
Authors: Yoshii Ryousuke , Nagai Atsushi , Tanaka Kazuo , Chujo Yoshiki 
Published: January 2013

AbstractA series of boron ketoiminate derivatives that exhibited clear aggregation‐induced emission (AIE) characteristics (in THF: ΦPL≤0.01; in the solid state: ΦPL=0.30–0.76) were prepared by the reactions of 1,3‐enaminoketone derivatives with boron trifluoride–diethyl etherate. The structures and optical properties were investigated by UV‐visible spectroscopy, photoluminescent (PL) spectroscopy, and X‐ray single‐crystal measurements. These results indicate that the AIE characteristics were derived from molecular motions of the boron‐chelating rings with a boronnitrogen (BN) bond. Furthermore, the optical properties were controllable by steric hindrance of the substituted groups on the nitrogen atom.