bluuebunny/crossref_metadata_2025_split huggingface dataset:
Parental involvement in college planning
Authors: M. Hines Erik , DiAnne Borders L. , M. Gonzalez Laura , Villalba José , Henderson Alia 
Published: November 2014

Purpose– The purpose of this article was to describe Hossler and Gallagher’s (1987) college choice model and emphasize the predisposition phase of the model as the starting point for school counselors’ efforts to help African American parents foster their children’s college planning in the college choice process.Design/methodology/approach– The authors wrote this manuscript as a conceptual approach to helping school counselors work with African American parents in their children’s college planning process by including two case studies as examples.Findings– This is a conceptual article.Practical implications– School counselors should be culturally competent and aware of how African Americans rear their children to help them successfully navigate college planning. For example, school counselors can learn about and share information with families about colleges that have support programs assisting African American students toward college completion.Originality/value– This paper is important to the field of education as it contributes to the literature regarding how school counselors can assist students in becoming college and career ready by working with their parents using a college choice model.
The Securities and Exchange Commission (“SEC”) prevails in the second circuit in defending its no-admission settlement policy
Authors: Healy Terence , J. Greer Amy , Z. Herbst Daniel 
Published: November 2014

Purpose
– To explain the impact of a recent decision by the USA Court of Appeals for the Second Circuit on the SEC’s “neither admit nor deny” practice on SEC enforcement matters after the practice was called into question by a federal district court judge.

Design/methodology/approach
– Explains the background on the practice of no-admission, the challenge by Judge Rakoff to the practice, and the ruling of the Second Circuit and its practical approach on enforcement matters.

Findings
– The ruling should resolve much of the uncertainty that has surrounded court approval of SEC settlements since Judge Rakoff’s decision to question the practice of no-admit or deny settlements. However, recent comments from SEC Chair Mary Jo White and Senior Enforcement Staff suggest that the SEC may continue to seek admissions in certain cases.

Originality/value
– Practical guidance from experienced securities and financial services lawyers.
Identifying entrepreneurs through risk taking behaviour: illegal downloading
Authors: Pascoe Kate , Mortimer Kathleen 
Published: November 2014

Purpose– This paper aims to explore, and is the first in a series, whether it is possible to use risk-taking activities as way of identifying potential entrepreneurs. The research examines the motivations of individuals to engage in deviant consumer behaviour, in this case illegal downloading and the link between this behaviour and possible entrepreneurial characteristics.Design/methodology/approach– The methodology approach was of a quantitative nature using a 32-item questionnaire disseminated to 215 undergraduate students at a UK university.Findings– Although there was strong evidence of entrepreneurial traits existing across the participants, including risk-taking propensity, no relationship could be found between risk-taking propensity and illegal downloading. Reasons put forward for these findings were that the level of risk involved was too low to be identified as such by the downloaders, even though the non-downloaders were worried about being caught and, therefore, were not participating in it. Attitudes towards this misbehaviour change when it is not for their own consumption and very few students participated in that activity.Research limitations/implications– This study is limited to a cohort of undergraduate students at only one university. This study begins to understand the potential link between misbehaviour and entrepreneurial traits.Originality/value– This paper examines the possible link between consumer misbehaviour, in this case illegal downloading and the display of entrepreneurial risk-taking characteristics. The implication of “consumer misbehaviour” through illegal downloading being “entrepreneurial” has, to our knowledge, not been previously tested and could be a useful and inexpensive way of identifying future entrepreneurs and consequently directing relevant support and training to the right people.
Scalable decision support for digital preservation
Authors: Becker Christoph , Faria Luis , Duretec Kresimir 
Published: November 2014

Purpose– Preservation environments such as repositories need scalable and context-aware preservation planning and monitoring capabilities to ensure continued accessibility of content over time. This article identifies a number of gaps in the systems and mechanisms currently available and presents a new, innovative architecture for scalable decision-making and control in such environments.Design/methodology/approach– The paper illustrates the state of the art in preservation planning and monitoring, highlights the key challenges faced by repositories to provide scalable decision-making and monitoring facilities, and presents the contributions of the SCAPE Planning and Watch suite to provide such capabilities.Findings– The presented architecture makes preservation planning and monitoring context-aware through a semantic representation of key organizational factors, and integrates this with a business intelligence system that collects and reasons upon preservation-relevant information.Research limitations/implications– The architecture has been implemented in the SCAPE Planning and Watch suite. Integration with repositories and external information sources provide powerful preservation capabilities that can be freely integrated with virtually any repository.Practical implications– The open nature of the software suite enables stewardship organizations to integrate the components with their own preservation environments and to contribute to the ongoing improvement of the systems.Originality/value– The paper reports on innovative research and development to provide preservation capabilities. The results enable proactive, continuous preservation management through a context-aware planning and monitoring cycle integrated with operational systems.
5‐Fluorouracil combined with apigenin enhances anticancer activity through mitochondrial membrane potential (ΔΨm)‐mediated apoptosis in hepatocellular carcinoma
Authors: Hu Xiao‐Yun , Liang Ji‐Yun , Guo Xue‐Jun , Liu Li , Guo Ya‐Bing 
Published: November 2014

SummaryThe development of chemoresistance may reduce the efficacy of chemotherapeutic drugs for treating hepatocellular carcinoma (HCC). In the present study, the effects of apigenin on intensifying the chemosensitivity of HCC cells and an HCC xenograft model in response to 5‐fluorouracil (5‐FU) were investigated. Sub‐toxic concentrations of apigenin (4 μmol/L) significantly enhanced the cytotoxicity of 5‐FU (100 μg/mL) in HCC cells. In vivo, combined treatment with apigenin (20 mg/kg, five times/week for 3 weeks) and 5‐FU (20 mg/kg for 5 consecutive days) significantly inhibited the growth of HCC xenograft tumours. Annexin V–propidium iodide dual staining assays, terminal deoxyribonucleotidyl transferase‐mediated dUTP–digoxigenin nick end‐labelling assays and western blotting analysis were used to confirm the synergistic effects of apigenin and 5‐FU on HCC apoptosis. Coincubation of HCC cells with apigenin and 5‐FU increased levels of reactive oxygen species (ROS), which was followed by a decrease in the mitochondrial membrane potential (ΔΨm). In addition, combined triggered the mitochondrial apoptotic pathway, as indicated by decreased Bcl‐2 expression and loss of ΔΨm, with significant activation of caspase 3 and poly(ADP‐ribose) polymerase. The present study is the first to demonstrate that apigenin may potentiate the cytotoxicity of 5‐FU in HCC via inhibition of ROS‐mediated drug resistance and concurrent activation of the mitochondrial pathways of apoptosis.
Sleep quality in patients with psoriatic arthritis
Authors: Gezer Orhan , Batmaz İbrahim , Sariyildiz Mustafa Akif , Sula Bilal , Ucmak Derya , Bozkurt Mehtap , Nas Kemal 
Published: November 2014

AbstractAimThe purpose of this study was to determine the effects of psoriatic arthritis (PsA) on sleep quality and investigate the association between sleep quality and clinical parameters of PsA, quality of life and psychological state in patients with PsA.MethodForty‐one patients with PsA and 38 healthy volunteers were included in this study. In both patients and healthy controls, sleep quality was assessed by means of the Pittsburgh Sleep Quality Index (PSQI) and anxiety and depression were assessed by means of the Hospital Anxiety and Depression Scale (HADS). In addition, PsA Quality of Life (PsAQoL) Index and Psoriasis Area and Severity Index (PASI) were used on patients. Generalized pain was assessed by means of a visual analogue scale (VAS).ResultsSubjective sleep quality, sleep latency, sleep duration, habitual sleep efficiency, sleep disturbance, daytime dysfunction and total PSQI scores were significantly higher in patients with PsA compared to healthy controls. Total PSQI scores significantly correlated with anxiety, generalized pain, PsAQoL scores, enthesitis and levels of C‐reactive protein (CPR) and erythrocyte sedimentation rate (ESR) (P < 0.05). Also, multiple regression analysis indicated that ESR level was independently associated with total PSQI score (P < 0.05, R2 = 0.325).ConclusionSleep quality is diminished in patients with PsA. Sleep disturbance is particularly associated with generalized pain, anxiety, enthesitis and levels of CRP and ESR in patients carrying the diagnosis of PsA.
Printing soil: a single‐step, high‐throughput method to isolate micro‐organisms and near‐neighbour microbial consortia from a complex environmental sample
Authors: Ringeisen Bradley R. , Rincon Karina , Fitzgerald Lisa A. , Fulmer Preston A. , Wu Peter K. 
Published: November 2014

Summary

Traditional high throughput methods for isolating microorganisms from environmental samples such as soil or sediment require pre‐processing steps to remove the living species from their solid‐phase microniche, creating a liquid‐phase sample. This process destroys near‐neighbor relationships that could be crucial to culturing and studying the microorganisms to be isolated.

An automated, high throughput method is described here that isolates pure microbial cultures and spatially related microbial consortia directly from a solid‐phase complex environmental sample. By using an orifice‐free printing mechanism, Biological Laser Printing (BioLP) enabled single‐step isolation of viable environmental microorganisms directly from soil. Soil was spread onto a titania‐coated quartz plate prior to initiating printing of soil micro‐particles with focused ultraviolet laser pulses.

Tunable amounts of soil were printed to glass slides, Luria Bertani agar plates and broth filled 96‐well plates at deposition rates exceeding 20 micro‐particles per second, demonstrating the ability to isolate thousands of micro‐particles of soil in minutes. Viability, culturability and significant morphological diversity were demonstrated post‐printing.

Results show that single step soil printing can be used to (a) generate pure microbial cultures (isolates), and (b) isolate consortia from a micro‐ecological system that exists naturally in near‐neighbor proximity, undisturbed from the environmental sample.
Effects of sitagliptin on blood pressure and heart rate in response to intraduodenal glucose infusion in patients with Type 2 diabetes: a potential role for glucose‐dependent insulinotropic polypeptide?
Authors: Wu T. , Trahair L. G. , Bound M. J. , Deacon C. F. , Horowitz M. , Rayner C. K. , Jones K. L. 
Published: November 2014

AbstractAimsTo evaluate the effects of the dipeptidyl peptidase‐4 inhibitor sitagliptin on blood pressure and heart rate, measured during a previously reported study, in which the effects of sitagliptin during intraduodenal glucose infusion at the rate of 2 kcal/min on glucose homeostasis were examined in patients with Type 2 diabetes.MethodsA total of 10 people with Type 2 diabetes were studied on two different days, 30 min after oral ingestion of sitagliptin (100 mg) or placebo. Intraduodenal glucose was infused at 2 kcal/min (60 g over 120 min), and blood pressure, heart rate, plasma glucagon‐like peptide‐1 and glucose‐dependent insulinotropic polypeptide (total and intact), glucose, insulin and glucagon responses were evaluated.ResultsIn response to intraduodenal glucose infusion, heart rate (treatment effect: P = 0.001) and serum insulin concentration (treatment × time interaction: P = 0.041) were higher after sitagliptin treatment than placebo, without a significant difference in blood pressure, plasma glucagon or glucose. During intraduodenal glucose infusion, there was a substantial increase in plasma total glucose‐dependent insulinotropic polypeptide on both days (time effect: P < 0.001), but not in total glucagon‐like peptide‐1. After sitagliptin, plasma intact glucagon‐like peptide‐1 concentration increased slightly (treatment × time interaction: P = 0.044) and glucose‐dependent insulinotropic polypeptide concentration increased substantially (treatment × time interaction: P = 0.003).The heart rate response to intraduodenal glucose was related directly to plasma intact glucose‐dependent insulinotropic polypeptide concentrations (r = 0.75, P = 0.008).ConclusionsSitagliptin increased the heart rate response to intraduodenal glucose infusion at 2 kcal/min in people with Type 2 diabetes, which was associated with augmentation of plasma intact glucose‐dependent insulinotropic polypeptide concentrations. These observations warrant further clarification of a potential role for glucose‐dependent insulinotropic polypeptide in the control of the ‘gut–heart’ axis.
Evaluation of Adult versus Pediatric Transesophageal Echocardiography Probe Efficiency for Guiding Septal Puncture during Atrial Fibrillation Ablation
Authors: Guler Ekrem , Babur Guler Gamze , Demir Gultekin Gunhan , Kizilirmak Filiz , Gunes Hacı Murat , Barutcu İrfan , Turkmen Mehmet Muhsin , Kilicaslan Fethi 
Published: November 2014

PurposeTransesophageal echocardiography (TEE) has a pivotal role in invasive cardiology practice in terms of guiding a variety of procedures. It is challenging to perform TEE examination with sedated patients due to difficulties in cooperation and positioning the patient properly, therefore the risk of complications is escalated. We aimed to assess the impact of pediatric TEE probe utilization on procedural success and complication rates; in comparison with conventional adult TEE probe.MethodsFifty‐eight patients undergoing atrial fibrillation (AF) ablation with TEE guidance were enrolled and patients were grouped based on probe size: Group 1 (n = 35) included patients undergoing the procedure with adult TEE probe guidance and Group 2 (n = 23) included patients with pediatric TEE probe guidance. Procedural success, postprocedural odynophagia and periprocedural intra‐oral bleeding frequency, number of intubation attempts, TEE imaging time, and midazolam doses for both groups were compared.ResultsOdynophagia frequency was significantly higher in Group 1 (25.7% [n = 9] vs. 0%, P = 0.008) besides oral mucosal bleeding was also higher in Group 1, although the difference did not reach statistical significance (5.7% [n = 2] vs. 0%, P = 0.513). Number of repeated attempts was lower in Group 2 (median, 1; range [3–1] vs. 1, [1–1], P = 0.038). Image resolutions and septal puncture success rates were similar for both groups. Total imaging time with TEE was significantly shorter in Group 2 (6.4 ± 1.8 min vs. 3.6 ± 0.9 min, P < 0.001). Midazolam dose was lower in Group 2 (7.0 ± 1.7 vs. 6.2 ± 1.7, P = 0.065).ConclusionUsing TEE probes with smaller size for guiding invasive percutaneous procedures performed in cardiac catheterization laboratory decreased TEE‐associated complication rates and enhanced patient comfort without any negative effect on procedural success.
Infective Endocarditis Related to a Coronary Artery Fistula with an Unusual Localization and Ectatic Coronary Arteries
Authors: Gerede Demet Menekse , Acibuca Aynur , Uzun Caglar , Goksuluk Huseyin , Ongun Aydan , Kilickap Mustafa , Erol Cetin 
Published: November 2014

Coronary artery fistulas (CAF) are a rare cardiac anomaly that can be either congenital or acquired. CAFs have clinical significance because of complications such as dyspnea on exertion, congestive heart failure, and cardiac tamponade. The literature also contains case reports of CAF presenting as bacterial endocarditis. We describe a 31‐year‐old man who presented with native valve infective endocarditis related to an unusual form of a CAF between the circumflex coronary artery and left ventricle. He also had giant coronary arteries, which were imaged with computed tomography angiography and transesophageal echocardiography. The diameter of the circumflex coronary artery and left main coronary artery was measured as 19 mm. Surgical intervention for heart valves was performed because of vegetations resistant to continued antibiotic treatment. At the same time, the CAF was treated with surgery.
Left Atrial Appendage Flow Velocity and Time from P‐Wave Onset to Tissue Doppler–Derived A' Predict Atrial Fibrillation Recurrence after Radiofrequency Catheter Ablation
Authors: Fukushima Keiko , Fukushima Noritoshi , Ejima Koichiro , Kato Ken , Sato Yasuto , Uematsu Shoko , Arai Kotaro , Manaka Tetsuyuki , Takagi Atsushi , Ashihara Kyomi , Shoda Morio , Hagiwara Nobuhisa 
Published: November 2014

BackgroundAtrial fibrillation (AF) is associated with atrial remodeling. We investigate the abilities of preprocedural echocardiographic parameters reflecting atrial remodeling to predict AF recurrence after radiofrequency catheter ablation (RFCA) for paroxysmal AF (PAF).MethodsPreprocedural echocardiographic parameters were measured during sinus rhythm in 105 patients with PAF undergoing RFCA. Electrical remodeling was assessed by the time from the onset of the P‐wave to the peak A′‐wave on the tissue Doppler imaging (PA‐TDI), functional remodeling was assessed by the left atrial appendage flow velocity (LAAFV), and structural remodeling was assessed by the left atrial volume index (LAVI). PA‐TDI, LAAFV, and LAVI values were divided into tertiles, and their abilities to predict AF recurrence were assessed using Cox regression analysis.ResultsAF recurrence occurred in 39/105 (37.1%) patients. After adjustment for confounders, the rate of AF recurrence was significantly higher in the highest tertile of PA‐TDI compared with the lowest tertile (≥151.3 msec vs. <131.0 msec; hazard ratio [HR]: 2.477, 95% confidence interval [CI]: 1.031–5.950; P = 0.042), and in the lowest tertile of LAAFV compared with the highest tertile (<48.5 cm/sec vs. ≥64.9 cm/sec; HR: 2.680, 95% CI: 1.136–6.318; P = 0.024). The risk of AF recurrence was also higher in the highest tertile of LAVI (≥34.2 mL/m2) compared with the lowest tertile, but this difference was not significant (HR: 2.146, 95% CI: 0.834–5.523; P = 0.113).ConclusionsLAAFV (reflecting functional remodeling) and PA‐TDI (reflecting electrical remodeling) are independent predictors of AF recurrence after RFCA for PAF.
Predictive Role of Stress Echocardiography before Carotid Endarterectomy in Patients with Coronary Artery Disease
Authors: Galyfos George , Tsioufis Constantinos , Theodorou Dimitris , Katsaragakis Stilianos , Zografos Georgios , Filis Konstantinos 
Published: November 2014

ObjectivesOur aim was to examine the predictive value of preoperative stress echocardiography regarding early myocardial ischemia and late cardiac events after carotid endarterectomy (CEA).MethodsPatients with coronary artery disease undergoing CEA were prospectively included in this study. All patients (n = 162) were classified into low, medium, and high cardiac risk group, according to preoperative stress echocardiography. Classification was based on the criteria of the American Society of Echocardiography. For all patients, cTnI was measured before surgery and on postoperative days 1, 3, and 7. Postoperative cTnI values ranging from 0.05 to 0.5 ng/mL were classified as myocardial ischemia; values >0.5 ng/mL were classified as myocardial infarction. Cardiac damage was defined as either myocardial ischemia or infarction.ResultsNo deaths, strokes, or symptomatic coronary events were observed during the early postoperative period. There were 112 low cardiac risk patients, 42 medium‐risk patients, and 8 high‐risk patients, according to stress echocardiography findings. Overall, there were 22 patients (14%) that increased their cTnI values postoperatively (12 of low cardiac risk and 10 of medium cardiac risk), and all of them were asymptomatic. None of the high‐risk patients showed any troponin increase. Late cardiac events were associated with cTnI increase, although no high‐risk patients showed any late event.ConclusionsPreoperative stress echocardiography does not seem to independently recognize patients in high risk for asymptomatic cardiac damage after CEA. Postoperative troponin elevation seems to be more predictive for late adverse cardiac events than preoperative stress echocardiography.
Evaluation of Peak Pressure Gradients in Patients after Melody Valve Implantation: A Comparison of Cardiac Catheterization and Doppler Echocardiography
Authors: Bauer Brenton S. , Zachariah Sybil , Levi Daniel , Rothman Abraham , Galindo Alvaro , Aboulhosn Jamil A 
Published: November 2014

ObjectivesThe aim of this study was to determine and quantify the relationship between Doppler echocardiography and cardiac catheterization measurements of the peak right ventricle‐pulmonary artery (RV‐PA) pressure gradient in patients within 24 hours of Melody valve implantation for treatment of a dysfunctional RV outflow tract (RVOT) conduit or bioprosthetic valve (BPV).BackgroundPatients with a dysfunctional RVOT conduit or BPV are now routinely treated percutaneously with implantation of a Melody valve. However, often the postimplantation catheter measurements of the RV‐PA peak gradient do not match the postimplant echo‐derived gradients obtained after completion of the procedure. Importantly, these echo gradients are commonly used to monitor patients after implantation over time.MethodsMedical records of 42 patients with Melody valve implantation were reviewed (men: 25/42; mean age: 22.4 ± 11.2 years; RVOT conduit: 23/42; BPV: 18/42; pulmonic stenosis: 6/42, pulmonic regurgitation: 3/42, both: 33/42).ResultsThe postimplantation RV‐PA peak gradient measured by Doppler echocardiography (within 24 hours of valve implantation) was significantly higher than the measurements acquired by catheterization immediately following implantation (24.2 ± 16.3 mmHg vs. 11.6 ± 8.5 mmHg, P < 0.0001). The relationship showed a moderate–strong correlation (r = 0.65, P < 0.0001) with regression analysis suggesting a linear association in both directions (echo gradient = 1.24 × cath gradient + 9.8, P<0.0001 vs. cath gradient = 0.34 × echo gradient + 3.4, P<0.0001).ConclusionThe Doppler echocardiography‐derived RV‐PA peak gradient within 24 hours of valve implantation is predictably higher than the catheter measured peak gradient immediately following valve implantation. A regression equation was derived to define this important relationship.