bluuebunny/crossref_metadata_2025_split huggingface dataset:
SnIV Porphyrin Scaffolds for Axially Bonded Multiporphyrin Arrays: Synthesis and Structure Elucidation by NMR Studies
Authors: Dvivedi Avanish , Pareek Yogita , Ravikanth Mangalampalli 
Published: March 2014

AbstractA simple, one‐step, supramolecular strategy was adopted to synthesize SnIV‐porphyrin‐based axially bonded triads and higher oligomers by using meso‐pyridyl SnIV porphyrin, meso‐hydroxyphenyl‐21,23‐dithiaporphyrin, and RuII porphyrin as building blocks and employing complementary and non‐interfering SnIVO and RuII⋅⋅⋅N interactions. The multiporphyrin arrays are stable and robust and were purified by column chromatography. 1H, 1H–1H COSY and NOESY NMR spectroscopic studies were used to unequivocally deduce the molecular structures of SnIV‐porphyrin‐based triads and higher oligomers. Absorption and electrochemical studies indicated weak interaction among the different porphyrin units in triads and higher oligomers, in support of the supramolecular nature of the arrays. Steady‐state fluorescence studies on triads indicated the possibility of energy transfer in the singlet state from the basal SnIV porphyrin to the axial 21,23‐dithiaporphyrin. However, the higher oligomers were weakly fluorescent due to the presence of heavy RuII porphyrin unit(s), which quench the fluorescence of the SnIV porphyrin and 21,23‐dithiaporphyrin units.
Iron Dicarbonyl Complexes Featuring Bipyridine‐Based PNN Pincer Ligands with Short Interpyridine CC Bond Lengths: Innocent or Non‐Innocent Ligand?
Authors: Zell Thomas , Milko Petr , Fillman Kathlyn L. , Diskin‐Posner Yael , Bendikov Tatyana , Iron Mark A. , Leitus Gregory , Ben‐David Yehoshoa , Neidig Michael L. , Milstein David 
Published: March 2014

AbstractA series of iron dicarbonyl complexes with bipyridine‐based PNN pincer ligands were synthesized and characterized by multinuclear NMR spectroscopy (1H, 13C, 15N, 31P), IR spectroscopy, cyclic voltammetry, 57Fe Mössbauer spectroscopy, XPS spectroscopy, and single‐crystal X‐ray diffraction. The complexes with the general formula [(R‐PNN)Fe(CO)2] (5: R‐PNN=tBu‐PNN=6‐[(di‐tert‐butylphosphino)methyl]‐2,2′‐bipyridine, 6: R‐PNN=iPr‐PNN=6‐[(diisopropylphosphino)methyl]‐2,2′‐bipyridine, and 7: R‐PNN=Ph‐PNN=6‐[(diphenylphosphino)methyl]‐2,2′‐bipyridine) feature differently P‐substituted PNN pincer ligands. Complexes 5 and 6 were obtained by reduction of the corresponding dihalide complexes [(R‐PNN)Fe(X)2] (1: R=tBu, X=Cl; 2: R=tBu, X=Br; 3: R=iPr, X=Cl; 4: R=iPr, X=Br) in the presence of CO. The analogous Ph‐substituted complex 7 was synthesized by a reaction of the free ligand with iron pentacarbonyl. The low‐spin complexes 5–7 (S=0) are diamagnetic and have distorted trigonal bipyramidal structures in solution, whereas in the solid state the geometries around the iron are best described as distorted square pyramidal. Compared to other structurally characterized complexes with these PNN ligands, shortened interpyridine CC bonds of about 1.43 Å were measured. A comparison with known examples, theoretically described as metal complexes bearing bipyridine π‐radical anions (bpy.−), suggests that the complexes can be described as FeI complexes with one electron antiferromagnetically coupled to the ligand‐based radical anions. However, computational studies, at the NEVPT2/CASSCF level of theory, reveal that the shortening of the CC bond is a result of extensive π‐backbonding of the iron center into the antibonding orbital of the bpy unit. Hence, the description of the complexes as Fe0 complexes with neutral bipyridine units is the favorable one.
Vortex‐Pattern Self‐Assembly in Mn‐Doped ZnSe Nanorods
Authors: Acharya Shinjita , Sarkar Suresh , Chakraborty Supriya , Pradhan Narayan 
Published: March 2014

AbstractSpontaneous patterning of anisotropic nanostructures into ordered assemblies remains a challenging quest, which requires controlled innovative approaches. One way to achieve such ordering of 1D nanorods is by manipulating the varieties of interactions (attractive and repulsive forces) present in colloidal solutions of anisotropic nanocrystals. The other ingenuous pathway is solvent‐evaporation‐mediated self‐organization of the 1D nanorods. By following the second protocol, we have achieved exclusive pillar self‐assembled patterns of visible‐light‐emitting Mn‐doped ZnSe nanorods. The nanorods also exhibit intriguing vortex patterning observed by directional solvent evaporation from the nanorod solution. The effect of solvent evaporation to generate such unique morphologies on the TEM grid is discussed and the reported procedure to obtain the assembled patterns of visible‐light‐emitting, doped nanorods might be useful for future technological applications.
Silica Nanowire Arrays for Diffraction‐Based Bioaffinity Sensing
Authors: Loget Gabriel , Corn Robert M. 
Published: March 2014

AbstractArrays of electrodeposited silica nanowires (SiO2 NWs) have been fabricated over large areas (cm2) on fluoropolymer thin films attached to glass substrates by a combination of photolithography and electrochemically triggered sol–gel nanoscale deposition. Optical and scanning electron microscopy (SEM) measurements revealed that the SiO2 NW arrays had an average spacing of ten micrometers and an average width of 700 nm with a significant grain structure that was a result of the sol–gel deposition process. The optical diffraction properties at 633 nm of the SiO2 NW arrays were characterized when placed in contact with solutions by using a prism‐coupled total internal reflection geometry; quantification of changes in these diffraction properties was applied in various sensing applications. Bulk refractive index sensing by using the SiO2 NW grating was demonstrated with a sensitivity of 1.30×10−5 RIU. Toposelectively chemically modified SiO2 NW arrays were used for diffraction biosensing measurements of surface binding events, such as the electrostatic adsorption of gold nanoparticles and the bioaffinity adsorption of streptavidin onto a biotin monolayer. Finally, the application of the SiO2 NW arrays for practical medical‐diagnostic applications was demonstrated by monitoring the diffraction of SiO2 NW arrays functionalized with a single‐stranded (ss)DNA aptamer to detect human α‐thrombin from solutions at sub‐pathologic nanomolar concentrations.
Highly Diastereoselective and Regioselective Copper‐Catalyzed Nitrosoformate Dearomatization Reaction under Aerobic‐Oxidation Conditions
Authors: Yang Weibo , Huang Long , Yu Yang , Pflästerer Daniel , Rominger Frank , Hashmi A. Stephen K. 
Published: March 2014

AbstractAn unprecedented copper‐catalyzed acylnitroso dearomatization reaction, which expands the traditional acylnitroso ene reaction and acylnitroso Diels–Alder reaction to a new type of transformation, has been developed under aerobic oxidation. Intermolecular and intra‐/intermolecular reaction modes demonstrate an entirely different N‐ or O‐acylnitroso selectivity. Hence, we can utilize this reaction as a highly diastereoselective access to a series of new pyrroloindoline derivatives, which are important structural motifs for natural‐product synthesis.
Merging Gold and Organocatalysis: A Facile Asymmetric Synthesis of Annulated Pyrroles
Authors: Hack Daniel , Loh Charles C. J. , Hartmann Jan M. , Raabe Gerhard , Enders Dieter 
Published: March 2014

AbstractThe combination of cinchona‐alkaloid‐derived primary amine and AuI–phosphine catalysts allowed the selective CH functionalization of two adjacent carbon atoms of pyrroles under mild reaction conditions. This sequential dual activation provides seven‐membered‐ring‐annulated pyrrole derivatives in excellent yields and enantioselectivities.
Mitigation of Iron Toxicity and Iron, Zinc, and Manganese Nutrition of Wetland Rice Cultivars (Oryza sativa L.) Grown in Iron‐Toxic Soil
Authors: Shahid Mohammad , Nayak Amaresh Kumar , Shukla Arvind Kumar , Tripathi Rahul , Kumar Anjani , Raja Rajagounder , Panda Bipin Bihari , Meher Jitendriya , Bhattacharyya Pratap , Dash Debiprasad 
Published: March 2014

AbstractWetland rice in many humid tropical regions of Asia, Africa, and South America are affected by iron toxicity, which mainly occur due to increase in Fe(II) concentration in soil solution resulting from drop of redox potential arising from anaerobic situations in submerged rice fields. The high quantity of ferrous ions in the soil solution upsets the mineral element balance in rice plants and affects its growth. A field experiment was carried out in acidic laterite soil (pH 5.1) having 400 mg kg−1 diethylene triamine pentaacetic acid extractable Fe for developing strategies to combat Fe toxicity and to study Fe, Zn, and Mn nutrition in rice. The treatments included four cultivars and six soil management options. Soil pH increased upon submergence and stabilized at 6.2 in compost treated plots and 6.8 in lime treated plots after eight weeks of flooding. Application of lime resulted significantly higher yields in all the four cultivars over control. Among the cultivars lowest Fe concentration both in grain and straw was recorded in tolerant as compared to susceptible cultivars. The ratio of Fe/Mn in rice plants was highest under control and reduced with Fe toxicity management treatments. It was further observed that Fe/Mn ratio of tolerant cultivars was lower as compared to susceptible cultivars irrespective of amendments. Similar relations were also recorded for Fe/Zn ratio under different Fe toxicity management interventions. Thus, the application of lime and limiting plant nutrients, such as K, Mn, and Zn along with tolerant cultivars could be important components of Fe toxicity management in Fe toxic acid lateritic soils.
Clinical outcomes of carbon ion radiotherapy for locally advanced adenocarcinoma of the uterine cervix in phase 1/2 clinical trial (protocol 9704)
Authors: Wakatsuki Masaru , Kato Shingo , Ohno Tatsuya , Karasawa Kumiko , Kiyohara Hiroki , Tamaki Tomoaki , Ando Ken , Tsujii Hirohiko , Nakano Takashi , Kamada Tadashi , Shozu Makio ,   The Working Group of the Gynecological Tumor
Published: March 2014

BACKGROUNDThis study sought to evaluate the toxicity and efficacy of carbon ion radiotherapy (C‐ion RT) for locally advanced adenocarcinoma of the uterine cervix in a phase 1/2 clinical trial.METHODSThe treatment consisted of whole‐pelvic irradiation of 36.0 gray equivalents (GyE) in 12 fractions and local boost with dose escalation from 26.4 to 38.4 GyE in 8 fractions. The dose escalation was performed with careful observation of acute normal tissue responses. Total dose to the cervical tumor was 62.4 to 74.4 GyE in 20 fractions.RESULTSBetween April 1998 and February 2010, 58 patients were treated with C‐ion RT in this clinical trial. The number of patients with stage IIB, IIIB, and IVA disease were 20, 35, and 3, respectively. Median tumor size was 5.5 cm (range, 3.0‐11.8 cm). Twenty‐seven patients had pelvic lymph node metastases. The median follow‐up period was 38 months. All patients completed the treatment schedule. Grade 2 or higher late toxicity was found in 8 patients: 5 with bladder and 2 with small intestine grade 2 toxicities, and 1 patient had grade 4 rectal complication, which was surgically salvaged. The 5‐year local control rate, local control rate including salvage surgery, and overall survival rate in all cases were 54.5%, 68.2%, and 38.1%, respectively.CONCLUSIONSDose escalation of C‐ion RT for adenocarcinoma of the uterine cervix was accomplished without severe toxicities except in 1 case. Although the number of patients in this study was small, the results support continued investigation and analysis to confirm therapeutic efficacy. Cancer 2014;120:1663–1669. © 2014 American Cancer Society.
Functional Corannulene: Diverse Structures, Enhanced Charge Transport, and Tunable Optoelectronic Properties
Authors: Sanyal Somananda , Manna Arun K. , Pati Swapan K. 
Published: March 2014

AbstractChemical functionalization of various hydrocarbons, such as coronene, corannulene, and so forth, shows good promise in electronics applications because of their tunable optoelectronic properties. By using quantum chemical calculations, we have investigated the changes in the corannulene buckybowl structure, which greatly affect its electronic and optical properties when functionalized with different electron‐withdrawing imide groups. We find that the chemical nature and position of functional groups strongly regulate the stacking geometry, π‐stacking interactions, and electronic structure. Herein, a range of optoelectronic properties and structure–property relationships of various imide‐functionalized corannulenes are explored and rationalized in detail. In terms of carrier mobility, we find that the functionalization strongly affects the reorganization energy of corannulene, while the enhanced stacking improves hopping integrals, favoring the carrier mobility of crystals of pentafluorophenylcorannulene‐5‐monoimide. The study shows a host of emerging optoelectronic properties and enhancements in the charge‐transport characteristics of functionalized corannulene, which may find possible semiconductor and electronics applications.
Robust Nonsticky Superhydrophobicity by the Tapering of Aligned ZnO Nanorods
Authors: Tian Jian , Zhang Yaping , Zhu Jie , Yang Zhongzhen , Gao Xuefeng 
Published: March 2014

AbstractThe robust nonsticky superhydrophobicity of aligned nanoneedle films is reported. A facile, efficient, cheap, and available method based on the diffusion‐limited crystal growth principle is proposed for controlling the tapering of ZnO nanorods, the profiles of which can be tuned effectively by synergetic control over reaction time and temperature in an extremely strong alkaline reaction system. The synthesized nanoneedle, nanopencil, and nanorod arrays are chosen for studying the effects of nanoscale topography on anti‐droplet‐sticking ability. After silanization, all of them show excellent quasi‐static anti‐droplet‐stickiness, and water adhesion along the normal and lateral directions can be greatly reduced by the tapering of nanorods and eliminated by sharp nanoneedles. However, their antisticking stability is distinct under the droplet impact: the nanoneedle sample is still nonsticky but the nanorod sample loses its antisticking ability. Only ensuring the liquid/air interface is in the suspended nonwetting state is insufficient to obtain robust nonsticky surfaces, which also require extremely low solid–liquid van der Waals attraction.
History Effects in Lithium–Oxygen Batteries: How Initial Seeding Influences the Discharge Capacity
Authors: Rinaldi Ali , Wijaya Olivia , Hoster Harry E. , Yu Denis Y. W. 
Published: March 2014

AbstractIn laboratory experiments, Li–O2 systems show “sudden death” at capacities far below the theoretical value. Identifying how discharge products limit the total capacity is crucial in Li–O2 system. We investigated the effect of Li2O2 seed layer deposited on carbon cathode under potentiostatic conditions at increasing overpotentials to the subsequent slow discharge at galvanostatic condition. The discharge capacity attainable in the second step is found to vary by more than a factor of 3 depending on the history, i.e., the seed layer. These results provide evidence that the battery history is decisive for the total discharge capacities.
Small Molecular Donors for Organic Solar Cells Obtained by Simple and Clean Synthesis
Authors: Demeter Dora , Mohamed Salma , Diac Andreea , Grosu Ion , Roncali Jean 
Published: March 2014

AbstractA small donor–acceptor molecule is synthesized in a two‐step procedure involving reaction of N,N‐diphenylhydrazine on 2,5‐diformylthiophene and Knoevenagel condensation. Results of UV/Vis absorption spectroscopy and cyclic voltammetry show that replacement of the phenyl ring bridge of a reference compound 2 by an azo group produces a slight red‐shift of λmax, an enhancement of the molecular absorption coefficient, and a decrease of the energy level of the frontier orbitals. A preliminary evaluation of the potentialities of compound 1 as donor material in a basic bilayer planar heterojunction cell of 28 mm2 active area using C60 as acceptor gave a short‐circuit current density of 6.32 mA cm−2 and a power conversion efficiency of 2.07 %.
Capacitance of p‐ and n‐Doped Graphenes is Dominated by Structural Defects Regardless of the Dopant Type
Authors: Ambrosi Adriano , Poh Hwee Ling , Wang Lu , Sofer Zdenek , Pumera Martin 
Published: March 2014

AbstractGraphene materials possess attractive properties that can be used for the fabrication of supercapacitors with enhanced energy‐storage performance. It has been shown that both boron and nitrogen doping of graphene can improve the intrinsic capacitance of the material relative to the undoped precursor. We address the question of whether p‐doping (using boron as dopant) or n‐doping (using nitrogen as dopant) leads to increased capacitance relative to undoped graphene materials. Using thermal exfoliation we synthesized both boron‐ and nitrogen‐doped graphene materials and measured capacitance relative to the undoped material. After a full characterization by SEM analysis, X‐ray photoelectron spectroscopy, Raman spectroscopy, gamma‐ray activation analysis, Brunauer–Emmett–Teller analysis, and electrochemical techniques we demonstrate that the doping process does not lead to enhancement of capacitive behavior and that the main characteristic influencing capacitance is the presence of structural defects within the graphitic structure, independent of doping level.
Towards a Sustainable Manufacture of Hierarchical Zeolites
Authors: Verboekend Danny , Pérez‐Ramírez Javier 
Published: March 2014

AbstractThe front cover artwork is provided by Dr. Danny Verboekend and Prof. Javier Pérez‐Ramírez of ETH Zurich. The image metaphorically expresses how sustainability plays a key role in reducing the synthetic footprint of hierarchical zeolites (HZ). The Full Paper itself is available at 10.1002/cssc.201301313
Pbx1 activates Fgf10 in the mesenchyme of developing lungs
Authors: Li Wei , Lin Chieh‐Yu , Shang Ching , Han Pei , Xiong Yiqin , Lin Chien‐Jung , Yang Jing , Selleri Licia , Chang Ching‐Pin 
Published: March 2014

SummaryInsufficiency of surfactants is a core factor in respiratory distress syndrome, which causes apnea and neonatal death, particularly in preterm infants. Surfactant proteins are secreted by alveolar type II cells in the lung epithelium, the differentiation of which is regulated by Fgf10 elaborated by the adjacent mesenchyme. However, the molecular regulation of mesenchymal Fgf10 during lung development has not been fully understood. Here, we show that Pbx1, a homeodomain transcription factor, is required in the lung mesenchyme for the expression of Fgf10. Mouse embryos lacking Pbx1 in the lung mesenchyme show compact terminal saccules and perinatal lethality with failure of postnatal alveolar expansion. Mutant embryos had severely reduced expression of Fgf10 and surfactant genes (Spa, Spb, Spc, and Spd) that are essential for alveolar expansion for gas exchange at birth. Molecularly, Pbx1 directly binds to the Fgf10 promoter and cooperates with Meis and Hox proteins to transcriptionally activate Fgf10. Our results thus show how Pbx1 controls Fgf10 in the developing lung. genesis 52:399–407, 2014. © 2014 Wiley Periodicals, Inc.
Influenza vaccine and survival in acute heart failure
Authors: Kopel Eran , Klempfner Robert , Goldenberg Ilan 
Published: March 2014

AimsInfluenza vaccine is a well‐recommended secondary prevention measure for improving survival in patients with coronary artery disease, but it has generally been less studied in heart failure. We ask whether having influenza vaccination is associated with survival among patients with acute heart failure (HF).Methods and resultsThis was a prospective population‐based cohort study accompanied by an analysis of two cross‐sectional population samples for external validation of baseline characteristics differences. We analysed all 1964 ambulatory patients with acute HF aged ≥50 years who were admitted to the Heart Failure Survey in Israel (HFSIS). We used the Israel Health Survey (IHS) 2009 and the Behavioural Risk Factor Surveillance System (BRFSS) 2003–2004 surveys (274 535 participants) for external validation. In the HFSIS, the multivariate‐adjusted hazard ratios for in‐hospital, 1 and 4 year mortality outcomes of influenza‐vaccinated patients were 0.71 (P = 0.19), 0.81 (P = 0.04), and 0.83 (P = 0.006), respectively. In the IHS validation sample, a recent physician visit [odds ratio (OR) 1.61; 95% confidence interval (CI) 1.43–1.80] or having supplementary health insurance (OR 1.39; 95% CI 1.19–1.61) were associated with higher likelihood of being vaccinated against influenza. In the BRFSS validation sample, having > 1 healthcare providers (OR 2.31; 95% CI 2.22–2.40) or having any healthcare coverage were associated with higher likelihood of being vaccinated (OR 1.59; 95% CI 1.54–1.65).ConclusionsInfluenza vaccine might improve survival among patients with acute HF. This association, however, could be affected by unmeasured confounding and bias due to baseline medical surveillance and socioeconomic differences between vaccinated and non‐vaccinated patients.
Plasma galectin 3 and heart failure risk in the Physicians' Health Study
Authors: Djoussé Luc , Matsumoto Chisa , Petrone Andrew , Weir Natalie L. , Tsai Michael Y. , Gaziano J. Michael 
Published: March 2014

AimsWe sought to test the hypothesis that plasma galectin 3 (Gal‐3) is positively associated with the risk of heart failure (HF) in male subjects.Methods and resultsWhile Gal‐3 has been reported as prognostic factor in HF patients, limited data are available on the role of Gal‐3 in the development of HF. We used a prospective nested‐case control study (n = 462 cases and 462 controls) within the Physicians' Health Study for current analyses. For each case of HF, we randomly selected one control among subjects that were alive and free of HF at the time of index case occurrence and matched on age, race, and time of blood collection. Gal‐3 was measured using ELISA and we used conditional logistic regression to compute adjusted odds ratios. Mean age at baseline was 58.3 y and median log‐Gal‐3 was 1.50 (IQR: 1.20–1.73) ng/ml. Cubic splines suggested a non‐linear relation between Gal‐3 and HF. Odds ratios (95% CI) for HF were 1.0 (ref), 0.89 (0.58–1.38), 1.08 (0.71–1.67), and 1.57 (1.03–2.39) across consecutive quartiles of Gal‐3 after adjustment for body mass index, diabetes, atrial fibrillation, hypertension, C‐reactive protein, alcohol, smoking, and exercise. The Gal‐3‐HF relation was seen for HF with and without antecedent coronary heart disease.ConclusionsOur data are consistent with a positive non‐linear association between Gal‐3 and HF risk in male subjects.