bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pretreatment Dysphagia Inventory and videofluorographic swallowing study as prognostic indicators of early survival outcomes in head and neck cancer
Authors: Yang Chan Joo , Roh Jong‐Lyel , Choi Kyoung Hyo , Kim Min‐Ju , Choi Seung‐Ho , Nam Soon Yuhl , Kim Sang Yoon 
Published: January 2015

BACKGROUNDThe prognostic role of swallowing‐related, pretreatment subjective and objective findings has not been investigated in detail. The authors evaluated the association between pretreatment MD Anderson Dysphagia Inventory (MDADI) or videofluorographic swallowing study (VFSS) results and standard outcomes, including early recurrence and survival, in patients with treatment‐naïve head and neck squamous cell carcinoma (HNSCC).METHODSPatients with HNSCC (n = 191) who received treatment at the authors' institution and were examined by self‐administered MDADI questionnaires and VFSS were prospectively enrolled. MDADI and VFSS findings were analyzed in correlation with clinicopathologic variables, and factors that predicted 2‐year disease‐free survival (DFS) and overall survival (OS) were identified using a Cox proportional‐hazards regression model.RESULTSThe 2‐year OS and DFS rates were 80.1% and 77.5%, respectively. Clinical tumor (T) and lymph node (N) classifications, overall TNM stage, sex, tumor site, and educational level were significantly associated with specific MDADI subdomains, whereas Karnofsky performance score was significantly associated with all MDADI subdomains. After controlling for clinical factors, total scores, global assessment scores, and emotional and physical MDADI subscores were significantly predictive of 2‐year OS and DFS (P < .05 for each). VFSS findings were not significantly associated with survival (P > .05).CONCLUSIONSThe current results provide evidence of the prognostic role of the MDADI in predicting early survival outcomes in patients with HNSCC. The MDADI may be a practical and noninvasive method for the identification of patients at risk who would benefit from close follow‐up. Cancer 2015;121:1588–1598. © 2015 American Cancer Society.
Sequential Linefeed Insertion into Lecture Transcriptions for Real‐Time Captioning
Authors: Ohno Tomohiro , Murata Masaki , Matsubara Shigeki 
Published: January 2015

SUMMARYTo generate readable captions for Japanese spoken monologues such as lectures in real time, it is necessary to sequentially display captions that have proper linefeeds inserted. This paper proposes a technique for sequentially inserting proper linefeeds into a lecture transcript whenever a bunsetsu, which is a linguistic unit shorter than a sentence in Japanese and that roughly corresponds to a basic phrase in English, is identified. Under the assumption that linefeeds are inserted at bunsetsu boundaries, this technique can reduce the delay time of captioning to the utmost possible. This technique statistically judges whether or not a linefeed should be inserted into each bunsetsu boundary by using the information that is available at the time. We conducted experiments on linefeed insertion using a Japanese lecture corpus. The experimental results confirmed that our method, which is a bunsetsu‐based linefeed insertion method, was almost as accurate as the sentence‐based linefeed insertion method. In addition, we conducted comparative evaluations using four baseline methods. The results confirmed that our method could insert linefeeds more accurately than the simple methods that are thought to have the same delay time as our method.
Design Technology of Stacked‐Type Chain PRAM
Authors: Kato Sho , Watanabe Shigeyoshi 
Published: January 2015

SUMMARYA stacked‐type chain PRAM that can result in lower cost than flash memory has been proposed. The newly proposed memory cell uses a PCM for data storage and an MOS transistor connected in parallel. This memory cell is connected in series to realize the chain structure. The cell structure, the design method for realizing stable read and write operation, and the core circuit for the stacked‐type chain PRAM are described. The newly proposed memory cell has been designed to use BiCS (Bit Cost Scalable) process technology in order to achieve low‐cost memory. The design of the resistance of the PCM and the pass transistor is a key issue for realizing stable operation. To design the row decoder, the circuit concept of stacked ferroelectric RAM (FeRAM) with an NAND structure cell has been successfully adopted with SGT. The newly proposed stacked‐type chain PRAM is a promising candidate for realizing high‐speed and low‐power future nonvolatile semiconductor memory.
Device Fabrication for Creating Multiscale Miniature Neuronal Networks and Spatiotemporal Pattern Analysis of Spontaneous Electrical Activities
Authors: Yoshida Lui , Kotani Kiyoshi , Jimbo Yasuhiko 
Published: January 2015

SUMMARYTo investigate the dynamics of neuronal networks, a device which is capable of multipoint simultaneous measurement and multiscale miniature neuronal network construction was fabricated. The results of culturing rat embryo hippocampal neurons showed that the device is biocompatible and can be successfully used in long‐term culture. Analysis of the electrical data obtained with the device suggested that, in miniature neuronal networks consisting of about 2000 neurons, there occurred spatiotemporal activity patterns of neurons, which were considered to be very important to the process of storing and transforming information of a brain.
Petroselinum crispum has antioxidant properties, protects against DNA damage and inhibits proliferation and migration of cancer cells
Authors: Tang Esther Lai‐Har , Rajarajeswaran Jayakumar , Fung ShinYee , Kanthimathi MS 
Published: January 2015

AbstractBACKGROUNDPetroselinum crispum (English parsley) is a common herb of the Apiaceae family that is cultivated throughout the world and is widely used as a seasoning condiment. Studies have shown its potential as a medicinal herb. In this study, P. crispum leaf and stem extracts were evaluated for their antioxidant properties, protection against DNA damage in normal 3T3‐L1 cells, and the inhibition of proliferation and migration of the MCF‐7 cells.RESULTSThe dichloromethane extract of P. crispum exhibited the highest phenolic content (42.31 ± 0.50 mg GAE g−1) and ferric reducing ability (0.360 ± 0.009 mmol g−1) of the various extractions performed. The extract showed DPPH radical scavenging activity with an IC50 value of 3310.0 ± 80.5 µg mL−1. Mouse fibroblasts (3T3‐L1) pre‐treated with 400 µg mL−1 of the extract showed 50.9% protection against H2O2‐induced DNA damage, suggesting its potential in cancer prevention. The extract (300 µg mL−1) inhibited H2O2‐induced MCF‐7 cell migration by 41% ± 4%. As cell migration is necessary for metastasis of cancer cells, inhibition of migration is an indication of protection against metastasis.CONCLUSIONPetroselinum crispum has health‐promoting properties with the potential to prevent oxidative stress‐related diseases and can be developed into functional food. © 2015 The Authors. Journal of the Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
Evaluation of peripheral microcirculation improvement of foot after tarsal tunnel release in diabetic patients by transcutaneous oximetry
Authors: Trignano Emilio , Fallico Nefer , CHEN HUNG‐CHI , Faenza Mario , Bolognini Alfonso , Armenti Andrea , Santanelli Di Pompeo Fabio , Rubino Corrado , Campus Gian Vittorio 
Published: January 2015

BackgroundAccording to recent studies, peripheral nerve decompression in diabetic patients seems to not only improve nerve function, but also to increase microcirculation; thus decreasing the incidence of diabetic foot wounds and amputations. However, while the postoperative improvement of nerve function is demonstrated, the changes in peripheral microcirculation have not been demonstrated yet. The aim of this study is to assess the degree of microcirculation improvement of foot after the tarsal tunnel release in the diabetic patients by using transcutaneous oximetry.Patients and methodsTwenty diabetic male patients aged between 43 and 72 years old (mean age 61.2 years old) suffering from diabetic peripheral neuropathy with superimposed nerve compression underwent transcutaneous oximetry (PtcO2) before and after tarsal tunnel release by placing an electrode on the skin at the level of the dorsum of the foot. Eight lower extremities presented diabetic foot wound preoperatively. Thirty‐six lower extremities underwent surgical release of the tibialis posterior nerve only, whereas four lower extremities underwent the combined release of common peroneal nerve, anterior tibialis nerve, and posterior tibialis nerve.ResultsPreoperative values of transcutaneous oximetry were below the critical threshold, that is, lower than 40 mmHg (29.1 ± 5.4 mmHg). PtcO2 values at one month after surgery (45.8 ± 6.4 mmHg) were significantly higher than the preoperative ones (P = 0.01).ConclusionsThe results of postoperative increase in PtcO2 values demonstrate that the release of the tarsal tunnel determines a relevant increase in microcirculation in the feet of diabetic patients. © 2015 Wiley Periodicals, Inc. Microsurgery 36:37–41, 2016.
Optically active helical vinyl polymers via radical polymerization of (S)‐3‐vinyl‐2,2′‐bisalkoxy‐1,1′‐binaphthyl
Authors: Chen Yehui , Qin Guochang , Yang Liwen , Yang Nianfa , Yang Zhusheng 
Published: January 2015

Abstract(S)‐3‐Vinyl‐2,2′‐bisalkoxy‐1,1′‐binaphthyl (3) was synthesized via the Wittig reaction. Radical polymerization of all the monomers can take place smoothly in the temperature region tested. These polymers (poly‐3) showed very large specific optical rotations which were four times as large as those of the corresponding monomers 3. Poly‐3 displayed optical rotations and Cotton effects in the UV−visible absorption region of side groups which were different from the corresponding monomers 3 and the model compounds (S)‐3‐ethyl‐2,2′‐bisalkoxy‐1,1′‐binaphthyl (4). These facts imply the formation of helicity of the main chain and the helical conformations were quite stable demonstrated by the unchanged pattern of temperature variable circular dichroism spectra. © 2015 Society of Chemical Industry
A GPU‐implemented physics‐based haptic simulator of tooth drilling
Authors: Razavi M. , Talebi H. A. , Zareinejad M. , Dehghan M. R. 
Published: January 2015

AbstractBackgroundRestorative dentistry simulation is one of the most challenging applications involving virtual reality and haptics. This paper presents a haptics‐based tooth drilling simulator for dental education.MethodsUnlike the existing methods, the force model is based on physical properties which consider the geometrical model of the tool. In order to provide uniform force feedback from tooth layers, a new approach is suggested in which the physical properties of each tooth voxel are subsequently used in calculating the feedback force. We implement a hashing algorithm for collision detection due to its reduced time complexity. The haptics algorithm has been implemented on a graphics processing unit using the CUDA toolbox.ResultsIn parallel processing, the speed of haptic loop execution is increased almost 8 times.ConclusionThe proposed idea for force calculation leads to a uniform sensation of force. An important feature of the designed system is the capability to run in a real‐time fashion. Copyright © 2015 John Wiley & Sons, Ltd.
A Series of Alkaline Earth Metal Ions Doped Cobalt(II) Heterometallic Cluster Complexes with N‐(phosphonomethyl) Iminodiacetic Acid and 1,3,5‐Benzenetricarboxylate Acid as Co‐ligands
Authors: Zhang Ai‐Qin , Li Sa‐Ying , Liu Zhi‐Hong 
Published: January 2015

AbstractThree alkaline earth metal ions doped CoII heterometallic cluster complexes and one monometallic magnesium cluster complex based on N‐(phosphonomethyl)imino‐diacetic acid (H4PMIDA) and 1,3,5‐benzenetricarboxylate acid (H3BTC) multifunctional ligands, [Co13Mg2(PMIDA)6(BTC)2(H2O)12]·6H2O (1), [Co13Ca2(PMIDA)6(BTC)2(H2O)12]·6H2O (2), [CoBa(PMIDA)(H2O)2]·H2O (3), and [Mg15(PMIDA)6(BTC)2(H2O)12]·6H2O (4) were synthesized under hydrothermal conditions and characterized by elemental analyses, IR spectroscopy, thermal analyses, and single‐crystal X‐ray diffraction. Compounds 1, 2, and 4 are basically isostructural and feature a cubic 3D open framework constructed by [M15(PMIDA)6(H2O)12] (M = Co13Mg2 for 1, Co13Ca2 for 2, and Mg15 for 4) clusters and BTC3– ligands. Compound 3 is characterized as a 3D framework containing rings with two tropisms along [010] and [101] directions, which are constructed by BaO6 chains and CoNO4 chains. Moreover, solid‐state fluorescent properties of these complexes were also investigated at room temperature, in which compound 4 exhibits the very strong emission band at 411 nm, and might serve as a candidate for hybrid inorganic‐organic fluorescent material.
VALUING EQUITY-LINKED DEATH BENEFITS IN A REGIME-SWITCHING FRAMEWORK
Authors: Siu Chi Chung , Yam Sheung Chi Phillip , Yang Hailiang 
Published: January 2015

AbstractIn this article, we consider the problem of computing the expected discounted value of a death benefit, e.g. in Gerber et al. (2012, 2013), in a regime-switching economy. Contrary to their proposed discounted density approach, we adopt the Laplace transform to value the contingent options. By this alternative approach, closed-form expressions for the Laplace transforms of the values of various contingent options, such as call/put options, lookback options, barrier options, dynamic fund protection and the dynamic withdrawal benefits, have been obtained. The value of each contingent option can then be recovered by the numerical Laplace inversion algorithm, and this efficient approach is documented by several numerical illustrations. The strength of our methodology becomes apparent when we tackle the valuations of exotic contingent options in the cases when (1) the contracts have a finite expiry date; (2) when the time-until-death variable is uniformly distributed in accordance with De Moivre's law.
Gene introduction into the mitochondria of Arabidopsis thaliana via peptide-based carriers
Authors: Chuah Jo-Ann , Yoshizumi Takeshi , Kodama Yutaka , Numata Keiji 
Published: January 2015

AbstractAvailable methods in plant genetic transformation are nuclear and plastid transformations because similar procedures have not yet been established for the mitochondria. The double membrane and small size of the organelle, in addition to its large population in cells, are major obstacles in mitochondrial transfection. Here we report the intracellular delivery of exogenous DNA localized to the mitochondria ofArabidopsis thalianausing a combination of mitochondria-targeting peptide and cell-penetrating peptide. Low concentrations of peptides were sufficient to deliver DNA into the mitochondria and expression of imported DNA reached detectable levels within a short incubation period (12 h). We found that electrostatic interaction with the cell membrane is not a critical factor for complex internalization, instead, improved intracellular penetration of mitochondria-targeted complexes significantly enhanced gene transfer efficiency. Our results delineate a simple and effective peptide-based method, as a starting point for the development of more sophisticated plant mitochondrial transfection strategies.
New human-specific brain landmark: The depth asymmetry of superior temporal sulcus
Authors: Leroy François , Cai Qing , Bogart Stephanie L. , Dubois Jessica , Coulon Olivier , Monzalvo Karla , Fischer Clara , Glasel Hervé , Van der Haegen Lise , Bénézit Audrey , Lin Ching-Po , Kennedy David N. , Ihara Aya S. , Hertz-Pannier Lucie , Moutard Marie-Laure , Poupon Cyril , Brysbaert Marc , Roberts Neil , Hopkins William D. , Mangin Jean-François , Dehaene-Lambertz Ghislaine 
Published: January 2015

Significance
In the human brain, from early in development through to adulthood, the superior temporal sulcus is deeper in the right than the left cerebral hemisphere in the area ventral of Heschl’s gyrus. Irrespective of gender, handedness, and language lateralization, and present in several pathologies, this asymmetry is widely shared among the human population. Its appearance early in life suggests strong genetic control over this part of the brain. In contrast, the asymmetry is barely visible in chimpanzees. Thus this asymmetry probably is a key locus to look for variations in gene expression among the primate lineage that have favored the evolution of crucial cognitive abilities sustained by this sulcus in our species, namely communication and social cognition.
A survey of current status of and perceived changes required for BIM adoption in the UK
Authors: Eadie Robert , Browne Mike , Odeyinka Henry , McKeown Clare , McNiff Sean 
Published: January 2015

Purpose– Construction organisations are mandated to use Building Information Modelling (BIM) for Government projects from 2016. The purpose of this paper is to investigate the current status of the management aspects of BIM.Design/methodology/approach– Following a telephone sift, a web-based questionnaire was conducted with UK construction BIM experts with 92 responses.Findings– This research demonstrates a paradigm shift in construction as operations were deemed more important than the technical aspects of BIM Adoption. Respondents agree with enforced Level 2 BIM, demonstrating client demand is a significant driver on uptake. BIM use will substantially increase in the next five years. Ranking of the importance of current BIM standards indicated BS1192 was most used but almost a third adopted individual standards producing fragmentation. BIM’s effect on consultant fees indicated the need for structural change.Practical implications– Front end design via BIM models and clash detection outweighed the use for facilities management indicating industry were meeting the target but not exploiting BIM to its full potential. Design and build and framework arrangements were the most common BIM procurement routes. Fragmentation of standards use creates a future interoperability problem between BIM systems.Social implications– Design team structure changes are supported with the adoption of a separate BIM manager being popular. Analysis of industry-wide model hosting characteristics indicated individual disciplines managed their own models meaning without an additional target for Level 3 BIM the single model environment is unlikely to be widely adopted.Originality/value– BIM fee structure and procurement are investigated for the first time
Changing consumer intake of potato, a focus group study
Authors: Fernqvist Fredrik , Spendrup Sara , Ekelund Lena 
Published: January 2015

Purpose
– While potato consumption in Europe and North America declines, other carbohydrate sources increase. The purpose of this paper is to explore factors affecting consumers’ changing consumption behaviour as regards fresh potato.

Design/methodology/approach
– Six semi-structured focus group interviews were conducted. Thematic analysis was made by means of a theory-driven approach.

Findings
– Seven categories of factors affecting consumer choice of fresh potato were found and discussed: first, convenience and preparation-related factors; second, health; third, information and packaging; fourth, sensory appeal; fifth, monetary considerations; sixth, familiarity and habit; and seventh, sustainability and ethics. Convenience appears to be the strongest explanation to changing food behaviour.

Research limitations/implications
– The research contributes to present knowledge regarding food choice and consumers’ carbohydrate intake. Findings of previous research is both validated and questioned. Methodological limitations are discussed, suggesting complementary quantitative approaches to the findings based on qualitative research.

Practical implications
– The findings add to knowledge of consumer behaviour and food choice. The findings may suggest focus areas in strategic marketing research, facilitating strategic decisions in response to falling consumption of fresh potatoes due to changing consumer attitudes and behaviour.

Originality/value
– By using a theory-driven approach in a thematic analysis, a broad set of interview data from six focus group interviews has been summarised and categorised. The methodology shows an effective way to treat a large amount of qualitative data and condense it to straightforward themes.
Prevalence of Listeria monocytogenes in different kinds of meat in Tehran province, Iran
Authors: Mashak Zohreh , Zabihi Ali , Sodagari Hamidreza , Noori Negin , Akhondzadeh Basti Afshin 
Published: January 2015

Purpose
– The purpose of this paper is to determine the prevalence of Listeria monocytogenes as an important foodborne pathogen in different kinds of meat.

Design/methodology/approach
– In total, 410 samples, including fresh and frozen meats of turkey, quail, chicken, ostrich, cattle, sheep and camel, fresh chicken liver and fresh minced meat were gathered and then analyzed according to USDA-FSIS method. To enumerate L. monocytogenes, the MPN procedure was used and also, strains were serotyped by using commercial specific antisera.

Findings
– It was found that 28.05 percent of samples were positive for L. monocytogenes and the contamination of beef meat was higher than the others. The range of microbial load was from <2 to 940 MPN g−1. Most of the samples (94.39 percent) had a microbial load of <100 MPN g−1. Moreover, 56 percent of the strains belonged to serogroup 1, especially to 1/2a, although, the most frequently isolated serotype was serotype 4b (38.3 percent) in all samples. These findings indicate the potential risk of contamination in different kinds of meats by L. monocytogenes.

Originality/value
– This survey is of academic value and of value to those working in the food hygiene and safety. Also, to the best knowledge of these researchers, there has been no serious research on this topic with all its aspects in Iran.
The relationship between pre-construction decision-making and the effectiveness of risk control
Authors: Lingard Helen , Saunders Lance , Pirzadeh Payam , Blismas Nick , Kleiner Brian , Wakefield Ron 
Published: January 2015

Purpose
– The purpose of this paper is to explore the relationship between the timing with which decisions are made about how to control work health and safety (WHS) risks in construction project (i.e. either pre- or post-construction) and the quality of risk control outcomes.

Design/methodology/approach
– Data were collected from 23 construction projects in Australia and the USA. Totally, 43 features of work were identified for analysis and decision making in relation to these features of work was mapped across the life of the projects. The quality of risk control outcomes was assessed using a classification system based on the “hierarchy of control”. Within this hierarchy, technological forms of control are preferable to behavioural forms of controls.

Findings
– The results indicate that risk control outcomes were significantly better in the Australian compared with the US cases. The results also reveal a significant relationship between the quality of risk controls and the timing of risk control selection decisions. The greater the proportion of risk controls selected during the pre-construction stages of a project, the better the risk control outcomes.

Research limitations/implications
– The results provide preliminary evidence that technological risk controls are more likely to be implemented if WHS risks are considered and controls are selected in the planning and design stages of construction projects.

Practical implications
– The research highlights the need for WHS risk to be integrated into decision making early in the life of construction projects.

Originality/value
– Previous research has linked accidents to design. However, the retrospective nature of these studies has not permitted an analysis of the effectiveness of integrating WHS into pre-construction decision making. Prospective studies have been lacking. This research provides empirical evidence in support of the relationship between early consideration of WHS and risk control effectiveness.