bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of Linear Quadratic Regulator and Model Predictive Control Based Algorithms in Continuous Production
Authors: Chindruş Amelia , Copoţ Dana , Căruntu Constantin-Florin 
Published: August 2024

Abstract
The integration of Industry 4.0 into manufacturing processes necessitates the automation of complex, large-scale operations within cyber-physical systems (CPSs). Pharmaceutical manufacturing, in particular, requires a transition from traditional batch processing to continuous manufacturing to achieve seamless integration with CPSs. This paper explores the comparison between two control strategies for pharmaceutical tablet production: the linear quadratic regulator (LQR) method and an established model predictive control (MPC) algorithm. The LQR method focuses on providing optimal stability and robustness for the plant’s operations, particularly through centralized management of key process units in the dry granulation process. A detailed plant model is utilized to test the performance of the LQR controller, with results benchmarked against those obtained using the MPC algorithm.
Addressing Fragmentation in Vietnam’s Data Protection Laws: Recommendations for a Unified Legal Framework
Authors: Hang Nguyen Ho Bich 
Published: August 2024

Abstract
In the digital economy, general and personal data are vital for the success of individuals and businesses. Inadequate personal data protection infringes on an individual’s fundamental rights and can jeopardize national security. Vietnam has enacted various measures but lacks a unified personal data protection law. This article examines Vietnam’s personal data framework, compares it with regulations from the European Union’s General Data Protection Regulation (GDPR), and references laws from Singapore, Thailand, and South Korea to highlight relevant legal matters.
Pengaruh Pemanfaatan Polimer Hdpe Terhadap Nilai Stabilitas Sebagai Subtitusi Aspal Pada Perkerasan Asphalt Concrete-Wearing Course (AC-WC)
Authors: Budi Santosa Teguh , Weimintoro Weimintoro 
Published: August 2024

Plastik atau polimer digunakan untuk campuran aspal sebagai larutan daur ulang dengan nilai fungsional yang ditingkatkan. Plastik yang akan digunakan adalah berjenis High Density Polyethylene (HDPE) yang banyak digunakan di kehidupan masyarakat. Dengan metode pencampuran basah, polimer HDPE disubstitusi dengan 4 variasi. Metode ini dilakukan guna mengetahui kadar terbaik berbagai campuran Plastik HDPE sesuai dengan Spesifikasi Ditjen Bina Marga Revisi 2 Tahun 2018. Dari seluruh hasil pengujian karakteristik Marshall, penambahan berbagai plastik HDPE sangat mempengaruhi naik turunnya hasil pengujian. Secara umum hasil yang paling mendekati sampel normal adalah variasi 4%. Pada kadar 4% nilai stabilitas sisa dapat memenuhi spesifikasi karena penambahan plastik HDPE pada aspal dapat mempengaruhi daya rekat benda uji dimana ketika direndam mampu mempertahankan bentuk dan kualitasnya.
Analisa Pengendalian Kualitas Menggunakan Metode Gugus Kendali Mutu Untuk Mengurangi Produk Cacat Di PT Gaya Teknik Logam
Authors: Zulfah Zulfah , Luthfianto Saufik , Sugiono M. Cipto , Siswiyanti Siswiyanti , Hidayat Tofik , Nurwildani M. Fajar 
Published: August 2024

PT Gaya Teknik Logam merupakan industri kecil menengah (IKM) yang bergerak dibidang manufaktur logam dengan produk yang dihasilkan yaitu berupa komponen otomotif. Salah satu jenis produk yang dihasilkan yaitu komponen standar tengah sepeda motor. Demi menjaga kepercayaan konsumen untuk menghasilkan produk yang berkualitas, perusahaan telah menerapkan manajemen mutu yang baik dan sesuai dengan pedoman standar mutu yang berlaku. Dalam kegiatan produksinya, perusahaan selalu berupaya agar menghasilkan produk yang baik dan menekan kerusakan produk, akan tetapi, kenyataan dilapangan seperti yang terjadi pada proses stamping banyak ditemukan produk yang dihasilkan tidak sesuai dengan standar yang telah ditetapkan. Penelitian ini bertujuan mengetahui bagaimana pelaksanaan pengendalian kualitas menggunakan metode Gugus Kendali Mutu (GKM) dalam upaya mengendalikan tingkat kerusakan produk di perusahaan. Permasalahan yang ada diselesaikan menggunakan seven tools yaitu check sheet, diagram pareto, p- chart, diagram sebab-akibat. Terdapat empat jenis cacat yang ditemukan pada proses stamping yaitu profil tidak sempurna, hasil piercing tidak centre, dakon dan scratch. Cacat profil tidak sempurna memiliki kontribusi terbesar dalam cacat produk yang terjadi pada komponen standar tengah sepeda motor yaitu mencapai 56,1%. Beberapa faktor penyebab produk cacat pada proses stamping yaitu faktor manusia, metode, mesin dan lingkungan. Jumlah cacat sebelum dilakukan perbaikan mencapai 3.073 pcs dari total produksi 259.622 pcs. Sedangkan setelah perbaikan mengalami penurunan dari total produksi sebesar 272.892 pcs mengalami kecacatan sebesar 451 pcs. Setelah dilakukan perbaikan terhadap faktor-faktor penyebab masalah, kerusakan produk pada proses stamping mengalami penurunan sebesar 85,3%.
Rancang Bangun Sistem Monitoring Suhu, Kelembaban, Dan Gerak Pada Cold Storage Berbasis Internet Of Things (IoT) Menggunakan Wemos D1 R2
Authors: Binardi Teguh , Syam Yusuf , Harahap Doly Andrian , Hakim Abdullah Farid 
Published: August 2024

Cold storage digunakan untuk menjaga dan menurunkan temperatur produk beserta kelembabannya agar kualitas produk tetap terjaga sampai pada waktunya dikirim ke konsumen. Pengontrolan temperatur pada cold storage menggunakan thermostat. Thermostat adalah suatu perangkat yang dapat memutuskan dan menyambungkan arus listrik pada saat mendeteksi perubahan suhu di lingkungan sekitarnya sesuai dengan pengaturan suhu yang ditentukan. Tujuan penulisan karya ilmiah ini adalah bertujuan untuk menciptakan suatu alat yang dapat memonitoring suhu, kelembaban, dan pendeteksi pergerakan didalam suatu ruangan khususnya ruang cold storage dimana bisa dimonitor via android, didalam rancangan alat ini penulis menggunakan sensor DHT22, sensor PIR HC SR501, dan mikrokontroler Wemos D1 R2 yang sudah berbasis ESP8266 yang bisa terkoneksi dengan WiFi, dimana arduino akan program melalui aplikasi Arduino IDE untuk menghasilkan suatu perintah pada komponen lainnya. Kegiatan praktik akhir yang dilaksanakan sejak tanggal 20 Februari 2023 – 20 Mei 2023 yang berlokasi di CV. Jaladra Teknik Bantul – D.I. Yogyakarta. Pengambilan data dan pengujian alat dilakukan di PT. ILM Mutiara Bahari yang cold storage-nya merupakan projek dari CV. Jaladra Teknik, hasil dari pengujian menunjukkan bahwa alat dapat berfungsi dengan baik dengan catatan jika panel mikrokontroler diletakkan di luar cold storage dan hanya sensor DHT22 dan sensor PIR HC SR501 yang diletakkan di dalam cold storage dimana pada alat akan mengirimkan data hasil pengujian di aplikasi blynk dan dicatat pada google sheet yang telah dirancang. Kesimpulan dari penelitian ini sudah berhasil merancang dan membuat sistem monitoring suhu cold storage berbasis IoT.
PERBEDAAN PEMBELAJARAN SINEKTIK DENGAN KONVENSIONAL TERHADAP KEMAMPUAN MENULIS PUISI SISWA SMAN 1 WANASARI KABUPATEN BREBES
Authors: , Ghufroni, dan Hany Uswatun Nisa Renastasya Larastanti 
Published: August 2024

Penelitian ini secara umum bertujuan untuk mengetahui tingkat keberhasilan dan kemampuan siswa praktik menulis puisi melalui penerapan model sinektik. Secara khusus penelitian ini bertujuan untuk mengetahui pengaruh penerapan model pembelajaran sinektik terhadap kemampuan menulis puisi siswa kelas X SMAN 1 Wanasari. Penelitian dilakukan dengan metode eksperimen dengan desain control group pretest-posttest design. Penelitian dilakukan pada siswa kelas X di SMAN 1 Wanasari Brebes. Populasi penelitian sebanyak 6 kelas dengan jumlah siswa sebanyak 216 siswa. Sampel penelitian diambil sebanyak 2 kelas dengan teknik kluster random sampling. Data diperoleh dengan test yang terdiri dari pretest dan postest. Analisis data menggunakan rumus uji-t dengan uji prasyarat meliputi uji normalitas dan uji homogenitas. Berdasarkan hasil analisis dan pembahasan, penelitian ini menyimpulkan bahwa ada pengaruh model pembelajaran sinektik terhadap kemampuan menulis puisi siswa kelas X SMAN 1 Wanasari Kabupaten Brebes.
UNSUR INTRINSIK DALAM NASKAH DRAMA KARLAK KARYA ALIN AMBARWATI DAN IMPLIKASINYA DALAM PEMBELAJARAN BAHASA INDONESIA DAN SASTRA DI SMA
Authors: Afsun Aulia Nirmala, dan Syamsul Anwar Tria Jaya, 
Published: August 2024

Abstrak
Karya sastra adalah sesuatu pemikiran yang di ungkapkan penulis yang dituangkan melaluiu tulisan dengan bahasa sastra, banyak sekali jenis karya sastra salah satu contohnya adalah naskah drama. Naskah drama adalah sebuah teks karangan penulis yang menceritakan tentang suatu kejadian yang di dalamnya berisi dialog-dialog dan beberapa tokoh yang ada di dalam cerita tersebut. Tujuan dari penelitian ini adalah untuk mendeskripsikan unsur intrinsik yang terdapat dalam naskah drama Karlak karya Alin Ambarwati. Penelitian ini menggunakan pendekatan deskriptif kualitatif. Sumber data penelitian ini adalah naskah Karlak karya Alin Ambarwati yang berupa prolog, dialog-dialog tokoh pada naskah drama yang mengandung unsur-unsur intrinsik. Berdasarkan uraian bab-bab sebelumnya dapat disimpulkan sebagai berikut. Unsur intrinsik dalam naskah drama Karlak Karya Alin Ambarwati meliputi tokoh, alur, latar, tema, bahasa, sudut pandang, amanat dan petunjuk teknis. Terdapat 8 tokoh yaitu : Waridi, Lastri, Darmi, Mimi, Dirjo, Dulloh, Badar, Juleha. Tema dalam naskah drama Karlak Karya Alin Ambarwati adalah status sosial. Latar dalam naskah drama Karlak Karya Alin Ambarwati diagi menjadi 3, yaitu latar waktu : pada pagi dan siang hari. Latar tempat : disebuah dermaga pelabuhan. Dan latar suasana : menegangkan. Alur dalam naskah drama Karlak Karya Alin Ambarwati tergolong bentuk alur Maju, karena diceritakan scara runtut dari awal hingga akhir. Bahasa dalam naskah drama Karlak Karya Alin Ambarwati adalah menggunakan bahasa indonesia dengan sedikit tambahan bahasa daerah tegal. Dialog yang digunakan berbahasa Indonesia. Untuk memberikan kesan Tegal, Alin Ambarwati menambahkan kata dari bahasa Tegal. Amanat yang dapat diambil dalam drama ini yaitu jangan menyebar fitnah karena bukan hanya diri sendiri yang dirugikan melainkan orang lain juga. Terdapat petunjuk teknis yang dapat digunakan untuk mendukung pementasan
Kata Kunci : Unsur Intrinsik, Naskah Drama, Implikasi
Role of Melatonin in Attenuation of Vascular Angiotensin 1-7 Reactivity Via Calcium Channels and Endothelial Derived Relaxing Factors in Induced Diabetic Aortic Rats
Authors: Mahmood Nazar M.Shareef , Mahmud Almas MR , Maulood Ismail M 
Published: August 2024

Melatonin (MEL) appears to have a regulatory role in vascular tone through enhancing endothelial-derived relaxing factors (EDRFs) and modulation of calcium (Ca2+) influx in both vascular smooth muscle cells (VSMCs) and vascular endothelial cells (VECs). While, such effects on angiotensin 1-7 (Ang 1-7) vasoreactivity in the vascular endothelial dysfunction (VED) remained unclear. Therefore, the current study investigates the vasculoprotective action of MEL on Ang 1-7 dose response curve (DRC) via Ca2+ channels and EDRFs in streptozotocin (STZ)–induced diabetes mellitus (DM) in male albino rats’ isolated aorta. The present study included four experiments. Experiment I, included measurement of tunical intima-media thickness and the histological examination in non-DM, STZ-induced DM and STZ-induced DM treated with MEL. Experiment II included the measurement of the isometric tension using Ang 1-7 DRC with or without NG-nitro-L-arginine methyl ester (L-NAME), a nitric oxide (NO) inhibitor in the studied groups. Experiment III included the measurement of the isometric tension using Ang 1-7 DRC with or without indomethacin (IND), a non-selective cyclooxygenase (COX) inhibitor in the studied groups. Experiment IV included the measurement of the isometric tension using Ang 1-7 DRC with or without nifedipine (NIF), a voltage-dependent L-type Ca2+ channels blocker in the studied groups. The present study found that, MEL demonstrated protective effects against vascular stress through multiple mechanisms. These actions collectively contributed to the maintenance of vascular health, preservation of endothelial function, and prevention of vascular diseases. Also it modulated vascular response to Ang 1-7 by either antioxidant properties or Ca2+ vasomotion.
Green Synthesis of Zinc Oxide Nanoparticles from Lyngbya sp. and Their Antibacterial Activity
Authors: Al-Shammary M. A. , Al –Mayaly I. K. 
Published: August 2024

In this study, the antibacterial activity of zinc oxide (ZNo NPs) was evaluated. ZnO NPs are considered as one of the many multifunctional inorganic nanoparticles with potent antibacterial properties. ZnO NPs were synthesized from the Lyngbya sp. extract.Following the green synthesis method,several other methods were used to characterize the biologically produced ZnO nanoparticles, including X-ray diffraction (XRD), field emission scanning electron microscope (FE-SEM), atomic force microscopy (AFM), and UV–visible spectrophotometry (UV-Vis).The AFM results showed 52.09 nm diameter as an averagesize of ZnO NPs, while the shapes of NPs were irregular as revealed through the FE-SEM image.Also, using UV-visible a cut-off phenomenon of the biological synthesized ZnO was found to be around 265 nm. The antibacterial activity of ZnO NPs at 0.05, 0.025, 0.0125, 0.0062, 0.0031 and 0.0015 gm/mlconcentrations were also tested on both Escherichia coli (Gram-negative bacteria) and Staphylococcus aureus (Gram-positive bacteria). The results demonstrated the inhibitory effects of ZnO NPs on S. aureus at0.05,0.025,0.0125, and 0.0062 gm /ml with inhibition zone of 10 ,9 ,8 and 6 mm respectively.While the E. coli results showed a growth inhibition at 0.05, 0.025, 0.0125 and 0.0062 gm/ml concentration treatments of ZnO NPs, represented by 22, 20, 18 and 10 mm of inhibition zone respectively.
Hydrochemical study and Water quality of Tigris Channel at Al- Taji area, Northern Baghdad
Authors: Abbood Ayat K. , Abdullah Enaam J , Al-Paruany Kamal B 
Published: August 2024

The water quality of the Tigris Channel at Al-Taji area were studied in both periods (August, and March, 2022). Eight samples were collected from Tigris channels to investigate water quality and parameters such as electrical conductivity (EC), total dissolved solids (TDS), Temperature (T), hydrogen number (pH), Total Hardness (T.H), as well as significant cations (Ca2+, Mg 2+, Na+, and K+), significant anions (CO32-, HCO3 -, Cl- and SO42-) and Heavy metals (Cd, Pb, Fe, Zn, Ni and Cr). The results show that the maximum value of EC is 1182 (µS/cm) in Ch3 in the dry period, while the lowest value of EC is1105 (µS/cm) in Ch1 in the wet period. The hydrochemical formula of water samples in both periods is CaCl. In this study, the dominating cation is Ca2+, followed by Na+, Mg2+, and K+, whereas the dominant anion is Cl-, followed by SO42-, HCO3-, and CO3-. According to Piper's illustration, all water samples that fall in class (e) are arranged together for both periods (wet and dry) "Earth alkaline water with a higher percentage of alkali and a sulfate and chloride predominance." Finally, the WQI is rated excellent for the wet Tigris channel and good water for the dry Tigris channel.
Quasi Subordination Properties of Bi-Univalent Functions By Using Generalized Srivastava-Attiya Operator
Authors: Hameed Firas N. , Shehab Nihad H. 
Published: August 2024

In this paper, we conduct an investigation into a novel subclass of bi-univalent functions within the unit disk. The introduced subclass incorporates the generalized Srivastava-Attiya operator and satisfies specific quasi-subordination conditions. Through this study, the researchers determine the coefficient estimates and for functions within these subclasses and unveil new results by applying the operator to this particular subclass. The implications of these findings extend to complex analysis, number theory, and other branches of mathematics. Overall, this research significantly contributes to the theory of quasi-subordination of bi-univalent functions and enhances the understanding of the diverse applications of the Generalized Srivastava-Attiya Operator.
Antioxidant and Hepatoprotective Effects of Chitosan on High Fructose Induced Liver Damage in Albino Rats
Authors: AL-Kurdy Masar J. , Kazaal Meraim A. 
Published: August 2024

Chitosan is a biodegradable natural polymer with many advantages such as nontoxicity, biocompatibility, and biodegradability. The current study aimed to evaluate the role of chitosan in reducing or regulating liver disorders caused by high fructose.concentration. The study was performed on thirty-two Wistar male rats, weighing between 195-200gms. These rats divided into four groups: control group which was kept on distill water, group 2 (G2) dosed with 40% fructose, group 3 (G3) dosed with 250 mg/kg of chitosan and group 4 (G4) dosed with 40% fructose and 250 mg/kg chitosan. After four weeks of study the blood samples were taken by heart puncturing and then all animals were sacrificed and specimens from liver were taken and homogenized for Alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase activity (ALP), and superoxide dismutase (SOD) determination. Liver tissues blocks were prepared by paraffin method stained using hematoxylin and eosin (H&E) stain. Highest concentration of ALT, AST, ALP, and SOD was detected in group G2 while serum albumin level decreased in rats in that group. We also found clear histological disorders in the liver of rats of this group. A reduction in the liver damage in G4, as the role of chitosan (G3) in improving liver function was proven by converging the level of the studied indicators from its counterpart in the control group. It can be concluded that chitosan is a successful protective agent for liver function: as it reduced hepatic impairment resulting from the use of fructose.
Exploring the Therapeutic Landscape: A Systematic Review on the Anti-inflammatory Effects of Probiotics in Colitis-associated Colorectal Cancer
Authors: Suswita Rini 
Published: August 2024

Background: Cancer is the second-leading cause of mortality worldwide. The inflammatory process has a well-known correlation with colorectal cancer, with chronic inflammation leading to malignancy. Long-term colitis disease has a 2-3-fold higher risk of colorectal cancer. Inflammation is involved in the development and progression of colitis-associated colorectal cancer (CAC), with molecular mediators and cytokines contributing to carcinogenesis. A diet of dairy products, such as probiotics, has been linked to a decrease in the incidence of colorectal cancer. Probiotics, known for their ability to modulate gut microbiota and immune responses, could potentially disrupt the inflammatory microenvironment implicated in the progression of colorectal cancer. Methods: We searched three databases: PubMed, ScienceDirect, and Wiley Online Library, using the respective keywords. A total of 248 studies were screened for eligibility, and nine studies eventually met the criteria and were reviewed. The SYRCLE RoB Tools were used to assess the risk of bias in the included studies.Results: The present evidence showed that treatment with probiotics was considered to be able to ameliorate the inflammation occurring in the CAC progression, as reflected in the severity of clinical signs, the expression of inflammatory markers, and the regulation of some pathways.
PENGARUH ENVIRONMENTAL, SOCIAL, AND GOVERNANCE, DAN INTELLECTUAL CAPITAL TERHADAP MANAJEMEN LABA RIIL YANG DIMODERASI OLEH LEVERAGE
Authors: Putra Marchania Wily , Vinola Herawaty  
Published: August 2024

Tujuan dari penelitian ini adalah menggunakan leverage sebagai variabel moderasi untuk mengetahui bagaimana pengungkapan Environmental, Social and Governance, Intellectual Capital dan Leverage mempengaruhi manajemen laba riil Perusahaan-perusahaan yang terdaftar di Bursa Efek Indonesia untuk industri energi dari tahun 2020 hingga 2022 merupakan sampel yang digunakan dalam penelitian ini. Hasil penelitian ini adalah Environmental, Social and Governance berpengaruh negatif terhadap Manajemen Laba Riil, Leverage memperkuat pengaruh Negatif Environmental, Social and Governance terhadap Manajemen Laba Riil, Leverage berpengaruh positif signifikan terhadap Manajemen Laba Riil, Intellectual Capital tidak berpengaruh negatif terhadap Manajemen Laba Riil dan Leverage tidak memperkuat pengaruh negatif Intellectual Capital terhadap Manajemen Laba Riil.
Safety and efficacy of mechanical thrombectomy for acute ischemic stroke with volume over 50 mL and significant perfusion mismatch
Authors: Gonsales Douglas , Figueiredo Eberval Gadelha , Telles Joao Paulo Mota , Aguilar-Salinas Pedro , Aghaebrahim Nima Amin , Sauvageau Eric , da Silva Saul Almeida , Hanel Ricardo A. 
Published: August 2024

Background:
This study aims to address the safety and efficacy of mechanical thrombectomy (MT) in acute ischemic stroke with an established infarction equal to or >50 mL with a significant difference between penumbra and established infarction detected by perfusion cerebral computed tomography (CT) with the Rapid® system.

Methods:
This was a retrospective case–control study. Patients diagnosed with established and extensive ischemic stroke, defined by an ischemic volume equal to or >50 mL on CT or magnetic resonance imaging perfusion using the RAPID® system, were examined. The intervention group received endovascular interventional treatment with or without recombinant tissue plasminogen activator (rt-PA) in addition to standard therapy, and the control group received conservative treatment with or without rt-PA plus standard therapy.

Results:
A total of 59 patients were enrolled, including 38 in the intervention group and 21 in the control group. Baseline characteristics were similar between groups. Patient National Institutes of Health Stroke Scale at discharge was significantly different between the control (median 30, interquartile range [IQR] 13) and intervention group (median 8, IQR 14) (P < 0.001). Modified Rankin scale (mRS) scores were significantly different at discharge between intervention (median mRS 2, IQR 3) and controls (median mRS 5, IQR 1) (P = 0.002). These mRS differences remained significant at 90 days, with median (IQR) values of 2 (2.75) and 5 (1), respectively (P < 0.001).

Conclusion:
MT is safe and effective for large-core ischemic strokes with significant perfusion mismatch, leading to better functional outcomes without significant complications compared to the best medical treatment.
Unilateral percutaneous balloon kyphoplasty for thoracic osteoporotic vertebral compression fractures: A case report and literature review
Authors: Tombeng Marthinson Andrew , Lauren Christopher , Mahadewa Tjokorda Gde Bagus 
Published: August 2024

Background:
Unilateral percutaneous balloon kyphoplasty (PBK) is increasingly utilized for the management of osteoporotic vertebral compression fractures (OVCFs). Its potential advantages include procedural simplicity, reduced tissue trauma, and minimal radiation exposure.

Case Description:
A 59-year-old female with osteoporosis presented with back pain but was neurologically intact 2 weeks after a fall. The magnetic resonance imaging documented a thoracic 12 vertebral compression fracture that was successfully treated with a unilateral PBK.

Conclusion:
Unilateral PBK appears promising for managing OVCFs in the aging population and offers rapid pain relief, vertebral height restoration, and functional improvement.