bluuebunny/crossref_metadata_2025_split huggingface dataset:
If You Build It, Will They Come? Caribou Habitat Restoration for Pipeline Projects
Authors: Coupal Brian , Bentham Paula 
Published: December 2014

The federal Recovery Strategy for the Woodland Caribou (Rangifer tarandus caribou), Boreal Population in Canada, identifies coordinated actions to reclaim woodland caribou habitat as a key step to meeting current and future caribou population objectives. Actions include restoring industrial landscape features such as roads, seismic lines, pipelines, cut-lines, and cleared areas in an effort to reduce landscape fragmentation and the changes in caribou population dynamics associated with changing predator-prey dynamics in highly fragmented landscapes. Reliance on habitat restoration as a recovery action within the federal Recovery Strategy is high, identifying 65% undisturbed habitat in a caribou range as the threshold to providing a 60% chance that a local population will be self-sustaining. In alignment with the federal Recovery Strategy, Alberta’s Provincial Woodland Caribou Policy identifies habitat restoration as a critical component of long-term caribou habitat management.
Habitat restoration initiatives of Alberta’s historical industrial footprint within caribou ranges began in 2001 and have largely focused on linear corridors, including pipelines. Initiatives include revegetation treatments, access control programs and studies, and restricting the growth of plant species that are favourable to moose and deer, the primary prey for wolves. Habitat restoration for pipelines also includes pre-construction planning to reduce disturbance and create line-of-sight breaks, and construction techniques that promote natural vegetation recovery. Lessons learned from habitat restoration programs implemented on pipeline projects in northeastern Alberta will be shared as an opportunity to improve common understanding of restoration techniques, the barriers to implementation, and potential outcomes.
Using HPIR Class Composite Pipeline Systems to Overcome the Challenges of Rehabilitating or Replacing a Pipeline Across a Navigable Waterway and Environmentally Sensitive Wetlands
Authors: McIntosh Robin , Littlestar Gary , Ekelund Aron 
Published: December 2014

One of the biggest challenges that Pipeline Operators face is the rehabilitation or replacement of long, old pipeline segments that have restrictive right-of-way access, such as those crossing a major waterway or highway or through an environmentally sensitive area where traditional dig and replacement is not an option. Typically, these projects have limited options and have high associated costs. Pipeline downtime is also a major factor in the project planning. Horizontal Directional Drilling and lengthy environmental impact studies are two examples of costly and/or time-consuming activities common to these projects. Self-monitoring, high-pressure internal replacement (HPIR class) composite pipeline systems are a viable alternative for replacing these hard to access pipelines, with little disruption to the pipeline right-of-way. HPIR class composite systems are installed into the old pipeline in very long lengths, negating the requirement for multiple excavations along the pipeline.
Although inserted inside the old pipeline, they are not a simple plastic “liner”. They are fully structural, transporting high-pressure oil, gas and hazardous materials, with no dependence on the corroded steel pipeline. State and federal regulatory codes mandate the replacement of pipelines under certain conditions as part of the integrity management programs implemented as a result of the United States 2002 Pipeline Safety Act. However, these codes do not always consider the impact that traditional trenching and replacement has on public safety, nor on environmentally sensitive areas such as wetlands, national parks or endangered species habitats. This paper will address the following aspects of pipeline replacement, in hard-to-access areas, such as those that cross navigable waterways: 1) The traditional methods and limitations related to replacing the pipeline segments in hard-to-access areas 2) Composite technologies available today 3) Case study of replacement of regulated pipeline segments using HPIR class composite pipeline systems.
Fitness-for-Service of Unconstrained Shallow Dents
Authors: Bratton Joseph P. , Glass Mitch , Cote Edgar , Gallagher Andy , Harper William V. 
Published: December 2014

Current federal regulations in the U.S. require excavation of plain dents identified through in line inspection surveys based primarily on depth. Industry experience, and previous research, has shown that the depth of the dent, alone, is not sufficient to assess dent severity and that releases could occur at dents below the excavation threshold (Dawson, 2006). Canada’s National Energy Board released a safety advisory on June 18, 2010, to all companies under their jurisdiction regarding two incidents involving shallow dents. The safety advisory stated that all integrity management programs should be reviewed and updated where appropriate to address the threat posed by shallow dents. Similar incidents have raised awareness in the United States and elsewhere around the world.
This paper focuses on an extensive multi-year effort to analyze the fitness for service of unconstrained shallow dents on multiple pipeline systems. Fatigue and strain analyses were performed to determine the serviceability and estimate the remaining service life. The dents in this study included both topside dents and bottomside dents that were previously evaluated through excavation to be unconstrained. Results of the fatigue and strain assessments are presented, along with field results of dents that were chosen for excavation.
Comparison of the fitness for service results and subsequent excavation findings were performed to improve an ongoing campaign to prioritize several hundred in-service unconstrained dents. Maximum strain levels of the dents were calculated based on the geometry of the dent as determined by radial sensor measurements from in line inspection surveys. The results of the in-line inspection and field measurement comparisons were analyzed to determine the accuracy and possible adjustments of strain assessments for the ongoing fitness-for-service program.
Laboratory and Numerical Simulations of Pipeline Leakage Behaviour: Volatile Organic Compound (VOC) Migration Through Porous Media and Subsequent Atmospheric Dispersion
Authors: Brydie J. R. , Trottier S. , Jafari A. , Rizwan Tania , Derakhshesh Marzie 
Published: December 2014

The transport of diluent (i.e. condensate blend) and/or diluted bitumen (i.e. dilbit) using buried pipelines is common practice. Aerial surveys are conducted on a regular basis as a part of the leak detection strategy at Enbridge Pipelines. During these surveys, the pilot flies over the right-of-way to visually inspect the pipeline for leakage along the pipeline corridor. Beyond visual inspection, the detection of proximal indicators of leakage by using remote sensors mounted on the aircraft is proposed in order to further enhance visual aerial leak detection methods. These sensors are designed to detect volatile organic compounds (VOCs) which are expected to evolve, even from small liquid leaks within the shallow subsurface and subsequently reach the atmosphere. If these VOCs can be detected in the local atmosphere in the vicinity of a leak during aerial surveys, then small liquid leaks may be more easily identified, characterized and remediated. This study is aimed to characterize and model VOC movement through soil to quantify the amount of VOC concentration expected to diffuse into the atmosphere within the vicinity of leakage.
The experimental study consisted of the characterization of three organic fluids, and one type of soil material representative of that used in pipeline construction. Two types of dilbit with different viscosities, as well as a typical diluent (i.e. condensate), were used because these types of organic fluids are commonly transported using pipelines. Batch laboratory tests were conducted using glass screw top vessels in order to determine the concentration and organic species evolving from these fluids. Headspace VOC and other gas species were characterized after 24 hours following the addition of the fluid to the sealed vessel. Custom designed laboratory-based columns were constructed, based upon scaled down field dimensions, and were used to simulate fluid leakage. Fluid was injected at the base of each column, over which porous media was suspended. Each test characterized the migration of VOCs through the porous medium, VOC breakthrough at the surface and data allowed the calculation of VOC flux into the overlying headspace.
Columns were operated under closed and flow through modes. Data obtained from the laboratory experiments defined bounding parameters for numerical simulations comprising of decoupled subsurface and atmospheric models. Subsurface modelling of the experimentally simulated leakage event was refined and validated using experimental data and a larger scale field leak scenario was modeled. Data from the laboratory testing and subsurface numerical simulations was used to construct atmospheric dispersion models of a potential field leak simulation. All atmospheric dispersion modelling used a Gaussian Dispersion Model within the Polair Software package (Odotech Inc.).
Application of Tensile Strain Models to Multiple Grades of Pipelines
Authors: Zhang Wenwei , Zhang Zhenyong , Zhang Jinyuan , Yang Peng 
Published: December 2014

China National Petroleum Corporation (CNPC) has constructed large-diameter high-strength pipelines (X70 and X80) in the past decades in areas of seismic activities, mine subsidence, and slope movement using strain-based design (SBD) technology. More pipelines being constructed now traverse regions of active seismic activities, mine subsidence, slope movement, and discontinuous permafrost. CNPC is also interested in moving to linepipe grades higher than X80. In view of the recent development of various tensile strain models, work was undertaken to evaluate those models and determine the most appropriate models for current and future applications.
In this paper, selected tensile strain models are reviewed and evaluated against an experimental database. The database of 80 tests from public-domain publications contains both full-scale pipe tests and curved wide plate tests with 46 tests from high strength pipes (X80 and above). The calculated tensile strain capacity from the selected models was compared with the test data. The models were evaluated and the applicability of the models to the linepipes of different strength levels was discussed.
Dual Threshold Analysis and its Tuning Tool Development for Leak Detection
Authors: Gao Jianping , Chen Mike 
Published: December 2014

Dual threshold setting in CPM (Computational Pipeline Monitoring) systems is a concept to apply two kind of thresholds, namely steady state threshold and transient threshold setting to improve sensitivity during steady state operating period and reduce false alarm rate during transient operating period. Dual threshold implementation in CPM systems is not a trivial task since a real time pipeline may go through very complicated hydraulic scenarios. During design phase of dual threshold, the data set evaluated needs to cover on operational scenario long enough to represent the typical operation of the pipeline. The design process needs to include the design of transient/steady state switching, transient and steady state threshold, waiting time etc and tuning of those design parameter to achieve the optima. This calls for effective analysis to ensure its validity and a tuning tool development with user-friendly graphical user interface (GUI) to facilitate the tuning efforts from leak detection engineers.
This paper details the process from dual threshold design and analysis to tuning tool development and application of the tool in real time CPM systems. At first, the concept of dual threshold and its design process being employed in CPM systems are reviewed; Secondly the paper discusses an analysis approach in testing and evaluation of dual threshold design in current CPM systems with identification of room for improvement. Next, the paper elaborates the design and development of a dual threshold tuning tool to simplify the process with intensive application of the tool during the threshold tuning of real time CPM systems to improve the detectability of the current leak detection system, finally concludes with some closing remarks.
Overall Framework of Strain-Based Design and Assessment of Pipelines
Authors: Wang Yong-Yi , Liu Ming , Horsley David , Salama Mamdouh , Sen Millan 
Published: December 2014

Significant progress has been made in recent years in the development of tensile and compressive strain capacity models. These models, along with various methods of strain demand determination, form the basic building blocks for the strain-based design and assessment (SBDA) of pipelines. At the same time, gaps exist between the current industry practice and the data needed for the proper application of those models. Furthermore the current practice of independently determining the tensile strain capacity, compressive strain capacity, and strain demand may not accurately represent field conditions as these elements interact and influence each other as opposed to act independently.
Key elements related to SBDA are provided for the planning and execution of life-time integrity management of pipelines subjected to high longitudinal strains. The paper places emphasis on two aspects of SBDA: (1) overall framework and (2) considerations that are not adequately covered in the current general industry practices. The entire processes of SBDA, including but not limited to design, material specifications, construction, post-construction field monitoring, and mitigation are covered at high-levels to assist decision-making in practical projects. Detailed methodologies for executing components of SBDA are not covered in this paper, but can be found in the cited references.
Screening Dementia in the Outpatient Department: Patients at Risk for Dementia
Authors: Tai Shu-Yu , Huang Shu-Wan , Hsu Chia-Ling , Yang Chiu-Hsien , Chou Mei-Chuan , Yang Yuan-Han 
Published: December 2014

The targeted screening for individuals at the risks of having dementia would be crucial to the further public health issues for dementia. This study aimed to conduct a screening study in an outpatient department of a regional hospital to screen people who were at risk of developing comorbid dementia. Patients who visited Kaohsiung Municipal Ta-Tung Hospital (KMTTH) clinics during the period from June 1, 2013, to May 31, 2014, were invited to participate in this screening voluntarily. The trained interviewer collected all participants’ demographic characteristics and used the instrument of ascertainment of dementia 8 (AD8) to find out suspected dementia ones. The result showed a higher ratio (24.1%) of suspected dementia in the outpatient department of a hospital, 500 out of 2017 subjects, than that in the general population. The median (interquartile range) age was significantly higher in the suspected dementia participants (70, (62, 77)) compared to that in nonsuspected dementia ones (65, (60, 73)), and the probability of suspected dementia was significantly increasing with age(P < 0.001). Instead of screening dementia in general population, screening people at the risk of dementia could be the practicable and important issues in the care of dementia.
The Mind and Liver Test: A New Approach to the Diagnosis of Minimal Hepatic Encephalopathy in Resource-Poor Settings
Authors: Das Saurav , Ali Sajjadh M. J. , Seward James , Venkataraman Jayanthi 
Published: December 2014

Background and Aims. Minimal hepatic encephalopathy (MHE) is diagnosed using neuropsychometric tests or neurophysiological tests that are either inapplicable to illiterate patient population in resource-poor settings or require sophisticated and expensive equipment. The available tests assess discrete domains of mental impairment. Our aim was (a) to design a neuropsychometric test that measures all domains of mental impairment in MHE using one metric; (b) to evaluate its sensitivity, specificity, and reproducibility.Methods. The mind and liver test (MALT), a psychometric test assessing cognition, memory, and psychometric impairment, each on a scale of 20, was designed keeping in mind the requirements of a universal test. 40 cirrhotics and 36 controls were subjected to critical flicker frequency (CFF) and MALT in same sitting. ROC curve was plotted for MALT using CFF as gold standard. Bland-Altman plot was used to find test-retest agreement.Results. CFF values and MALT scores varied significantly between the cases and the controls(P< 0.05). MALT was 94% sensitive and 83% specific. Using ROC with CFF as gold standard, the AUC for diagnosis of MHE using MALT score was 0.89. Test-retest agreement was high (ICC = 0.89).Conclusion. In this pilot study, MALT proved to be highly sensitive, specific, inexpensive, and reproducible.
Asymptotic moment boundedness of the stochastic theta method and its application for stochastic differential equations
Authors: Qiu Qinwei , Liu Wei , Hu Liangjian 
Published: December 2014

Abstract
This paper is devoted to the study of reproduction of asymptotic boundedness in the second moment and small moments of stochastic differential equations by the stochastic theta method. In addition, we illustrate that the asymptotic moment boundedness of the numerical solution stand-alone plays a key role in the study of numerical stationary distribution.
Polymeric nanocarrier systems for photodynamic therapy
Authors: Li Li , Huh Kang Moo 
Published: December 2014

Abstract
Photodynamic therapy (PDT) is an emerging treatment modality that involves the combined action of photosensitizers (PSs) and light for treatment of solid tumor and other diseases. Although this therapeutic method has been considered as an alternative to classical cancer treatments, clinical PDT requires further advances in selectivity and therapeutic efficacy to overcome numerous shortages related to conventional PDT. In this regard, great efforts have been devoted to the development of polymeric nanocarrier-encapsulated PSs for targeted PDT, aiming at improvement of water solubility and tumor-specificity of hydrophobic PSs. Here, we discuss the general concepts and considerations of polymeric nanocarriers for efficient delivery of PSs. In recent, the amphiphilic PS-polymer conjugate-based self-quenchable nanoparticles and PS-polymer-conjugate/quencher nanocomplexes have emerged as an attractive delivery platform for efficient and reliable PDT. They can incorporate and deliver the PS in a photodynamically inactive state but demonstrate cytotoxic effects by tumor environment-sensitive activation mechanisms, so that the photodynamic cancer treatment can achieve maximum target specificity. Here, we report the recent achievements on the development of activatable PS formulations based on PS-polymer conjugates.
Molecular Characterization of Testicular Adrenal Rest Tumors in Congenital Adrenal Hyperplasia: Lesions With Both Adrenocortical and Leydig Cell Features
Authors: Smeets Evelien E. J. W. , Span Paul N. , van Herwaarden Antonius E. , Wevers Ron A. , Hermus Ad R. M. M. , Sweep Fred C. G. J. , Claahsen-van der Grinten Hedi L. 
Published: December 2014

Context:
Testicular adrenal rest tumors (TART) are one of the major long term complications in patients with congenital adrenal hyperplasia. Although several adrenal-like properties have been assigned to these benign lesions, the etiology has not been confirmed yet.

Objective:
The aim of this study was to describe TART in more detail by analyzing several (steroidogenic) characteristics that may be classified as adrenal cortex or Leydig cell specific.

Methods:
Gene expression analysis by qPCR was performed for 14 genes in TART tissue (n = 12) and compared with the expression in healthy control fibroblasts (nonsteroidogenic control). In addition, a comparison was made with the expression levels in testis tissue (n = 9) and adrenal tissue (n = 13).

Results:
Nearly all genes were highly expressed in TART tissue, including all genes that encode the key steroidogenic enzymes. TART expression levels are in the majority almost identical to those found in adrenal tissue. The expression of adrenal cortex specific genes (CYP11B1, CYP11B2, and MC2R) in both TART and adrenal tissue is approximately 1000–10 000 times higher compared to that in testes samples. In addition, the Leydig cell markers INSL3 and HSD17B3 were not only found in testes, but also in TART, both at significantly higher levels than in the adrenal (p &lt; 0.01).

Conclusion:
Our study shows for the first time that TART have multiple steroidogenic properties, which include not only the expression of adrenal cortex but also of Leydig cell markers. Therefore, the origin of these tumors might be a more totipotent embryonic cell type.
Muller’s phlebectomy
Authors: Perruchoud D. L. , Ramelet A.-A. 
Published: December 2014

SummaryMore than 50 years ago, the Swiss dermatologist Dr Robert Muller developed ambulatory phlebectomy, a brilliant demonstration of the major role of dermatologists in the field of phlebology. The technique is safe, reliable and cost-effective, while at the same time producing aesthetically pleasing results. Patients can usually resume normal daily activities immediately after the procedure or are off work for a few days at most. Indications for ambulatory phlebectomy include incompetent saphenous veins (except the junctions) and their tributaries, perforators, reticular veins and reticular feeder veins, large spider veins and dilated veins in other areas such as around the eyes, on the arms or on the back of the hands.The tiny skin incisions do not usually leave any scars or give rise to complications. Phlebectomy can be used alone or in combination with other procedures such as sclerotherapy, endovenous techniques and surgery.
Psychosomatic disorder in phlebology
Authors: Amsler F. , Blättler W. 
Published: December 2014

SummaryAccording to population-based studies, the prevalence of feelings of heaviness, swelling and pain in the legs is around 50 %. These feelings are often not accompanied by clinically detectable changes, but are the inevitable and generally unrecognised consequences of the increase in leg volume caused by standing still. We assume that the physiological change is detected as part of the constant information about the internal milieu that is sent to the corresponding centres in the brain. This information is modified by many factors, including emotion and – depending on the situation – is either appropriately perceived as an unpleasant sensation of swelling or not even noticed. These feelings can result in an impairment of vitality and depression. In some cases, a thorough phlebological work-up can reveal an occult organic venous disease, so that the feelings can be traced to a somatic cause. Feelings have a psychological and a somatic component; they are not imaginary. It is up to the doctor to discern the individual importance of the two components and to draw the appropriate conclusions regarding treatment.