bluuebunny/crossref_metadata_2025_split huggingface dataset:
Faktor Penyebab Cemas Pada Pekerja Wanita Usia Subur
Authors: Febriawati Henni , Wati Zulaikha Agustina , Angraini Wulan , Yanuarti Riska , Puteri Febyona Jolest 
Published: July 2024

ABSTRACT According to the East Java Province Communication and Information Service, in 2023 the number of female workers in East Java will increase by 0.47%. 56.11% of workers in East Java are women. This study aims to determine the factors of depression/anxiety in female workers of childbearing age (WUS) with an age range of 15-49 years. The research design used is mixed methods research by combining quantitative data (Self-Reporting Questionnaire (SRQ)-20 test) and qualitative data (in-depth interviews). The results of the Self-Reporting Questionnaire (SRQ)-20 test show that 3 out of 15 female workers of childbearing age experience depression/anxiety. The results of in-depth interviews (In-Depth Interview) show that there are factors that cause depression/anxiety in female workers of childbearing age, namely work factors and individual (family) factors. The conclusion of this research is that there is a relationship between depression/anxiety and reproductive health in female workers of childbearing age. Keywords: Anxiety, Women of Childbearing Age, Worker ABSTRAK Menurut Dinas Kominfo Provinsi Jawa Timur tahun 2023, jumlah pekerja wanita di Jawa Timur meningkat 0,47%. 56,11% pekerja di Jawa Timur adalah wanita. Tujuan penelitian ini untuk mengetahui faktor depresi/cemas pada pekerja Wanita Usia Subur (WUS) dengan rentang usia 15-49 tahun. Desain penelitian yang digunakan adalah mixed methods research dengan menggabungkan data kuantitatif (tes Self-Reporting Questionnaire (SRQ)-20) dan data kualitatif (wawancara mendalam). Hasil tes Self-Reporting Questionnaire (SRQ)-20 diperoleh 3 dari 15 orang pekerja wanita usia subur mengalami depresi/cemas. Hasil wawancara mendalam (In-Depth Interview) menunjukkan adanya faktor penyebab depresi/cemas pada pekerja wanita usia subur yaitu dikarenakan faktor pekerjaan dan faktor individu (keluarga). Kesimpulan dari penelitian ini adalah adanya hubungan antara depresi/cemas dengan kesehatan reproduksi pada pekerja wanita usia subur. Kata Kunci: Cemas, Pekerja, Wanita Usia Subur
Pengaruh Paparan Internet, Status Gizi, dan Aktivitas Fisik Terhadap Usia Menarche Pada Siswa Perempuan Kelas V dan VI di SDN Plawad II Karawang
Authors: Masruloh Masruloh , Ardianty Astuti Dwi 
Published: July 2024

ABSTRACT The purpose of this study was to determine the effect of internet exposure, nutrition, and physical activity on girls in grades V and VI at SDN Plawad II Karawang in 2022 at the age of menstruation. Analytical research with a cross-sectional approach is the method used. The research was conducted at SDN Plawad II Karawang. The research data uses a questionnaire sheet. The number of respondents was 68 people. By using the Chi Square test, data analysis statistical test results showed that variables related to internet exposure had a p value of 0.010, nutritional status had a p value of 0.041, and physical activity had a p value of 0.003 indicating that the p value is less than 0.05. Thus it can be concluded that internet exposure, nutritional status, and physical activity affect menstrual age in grades V and VI students at SDN Plawad II Karawang in 2022. The School Health Unit (UKS) seeks to improve communication, information, and education (IEC) with provide counseling to students on how to wisely use the internet and live a healthy life with balanced nutrition. Keywords:Compliance, Triple Elimination, Integrated ANC, Pregnant Women ABSTRAK Tujuan dari penelitian ini adalah untuk mengetahui pengaruh paparan internet, gizi, dan aktivitas fisik pada anak perempuan kelas V dan VI di SDN Plawad II Karawang tahun 2022 pada usia menstruasinya. Penelitian analitik dengan pendekatan cross-sectional adalah metode yang digunakan. Penelitian dilakukan di SDN Plawad II Karawang. Data penelitian menggunakan lembar Kuesioner. Jumlah responden sebanyak 68 orang. Dengan menggunakan Uji Chi Square, analisis data Hasil uji statistik menunjukkan bahwa variabel yang berkaitan dengan paparan internet memiliki nilai p 0,010, status gizi memiliki nilai p 0,041, dan aktivitas fisik memiliki nilai p 0,003 yang menunjukkan bahwa nilai p kurang dari 0,05. Dengan demikian dapat disimpulkan bahwa paparan internet, status gizi, dan aktivitas fisik berpengaruh terhadap usia menstruasi pada siswa kelas V dan VI di SDN Plawad II Karawang tahun 2022. Unit Kesehatan Sekolah (UKS) berupaya meningkatkan komunikasi, informasi, dan edukasi (KIE) dengan memberikan penyuluhan kepada siswa tentang cara bijak menggunakan internet dan hidup sehat dengan gizi seimbang. Kata Kunci: Aktivitas Fisik, Keterpaparan Internet, Status Gizi, Usia Menarche
Analisis Tingkat Kepuasan Pasien Rawat Inap Terhadap Kualitas Pelayanan Gizi di RSD Idaman Banjarbaru
Authors: Prihandini Yustin , Torizellia Cast , Riyana Adies , Susiana Nadia 
Published: July 2024

ABSTRACT Nutrition services in hospitals are one of ten facilities and services that must be available in hospitals. Identifying the description of respondents in terms of age, gender and occupation as well as a description of the quality of service at the inpatient hospital at Idaman Banjarbaru Hospital. This type of research is descriptive observational. The sample in this study was 60 inpatients at Idaman Hospital, Banjarbaru City. The sample in this study used an accidental sampling technique. Measuring tools/instruments with questionnaires distributed to the sample. Inpatients Have a High Level of Satisfaction with the Quality of Nutrition Services at RSD Idaman Banjarbaru. Keywords: Gizi, Pelayanan, Rumah Sakit ABSTRAK Pelayanan Gizi di rumah sakit adalah satu dari sepuluh fasilitas dan pelayanan yang harus ada di rumah sakit. Mengidentifikasikan gambaran responden dari segi umur, jenis kelamin, dan pekerjaan serta gambaran kualitas pelayanan di rawat inap RSD Idaman Banjarbaru. Jenis penelitian ini adalah observasional yang bersifat deskriptif, Sampel dalam penelitian ini adalah 60 pasien rawat inap di RSD Idaman Kota Banjarbaru. Sampel dalam penelitian ini menggunakan teknik accidental sampling Alat ukur / Instrumen dengan kuesioner yang disebar pada sampel. Pasien Rawat Inap Memiliki Tingkat Kepuasan Yang Tinggi Terhadap Kualitas Pelayanan Gizi Di RSD Idaman Banjarbaru Kata Kunci: Nutrition, Service, Hospital
Secure Travel Planning Using a Heuristic Algorithm
Authors: Mahdi Ali Jamal , Esztergár-Kiss Domokos 
Published: July 2024

Security perception in the urban area has a significant effect on travel behaviour, preferences, and tour planning. The perceptions of security risks can vary depending on factors, such as age, gender, and previous experiences. This study aims to consider security risks when developing travel plans and schedules for various activities. An improved heuristic algorithm, based on the Travelling Salesman Problem with security parameter and flexibility aspects, is proposed. Public transport is considered in three situations: fixed, flexible, and flexible-security situations. The outcomes demonstrate that the flexible situation significantly decreases travel times by 21% compared to the basic (fixed) situation. At the same time, with a slightly increased travel time the security risk can be avoided in the flexible-security situation. Travelers can enjoy a higher quality of travelling and enhanced personal experience by minimizing the journey duration and the impact of security risks on the tour schedule. The proposed method provides significant benefits for transport operators by increasing the efficiency of the transportation system and higher customer satisfaction.
Identification of Bacteria Capable of Chromium Bioremediation from the Environment
Authors: Ahsan Sunjukta , Mohona Ellin Ferdous , Shaon Md Asifur Rahman , Turzo S M Syed Muktadir , Rahman Sahriar 
Published: July 2024

With the increased urbanization and industrial development, the environment is getting polluted severely day by day. In Bangladesh, the capital city Dhaka is surrounded by a circular river system, most of which are highly polluted due to discharge of municipal and industrial untreated waste water that has been overloaded with different types of toxic heavy metals. Cr (VI) being used in various activities of industries and its improper treatment lead to contamination of the environment. This study aimed to isolate bacteria with chromium bioremediation potential from the environment. A total of 71 bacteria were isolated, of which all grew in the presence of 100 ppm, 93% in 200 ppm, 46% in 400 ppm, 6% in 600 and 4% in 1000 ppm chromium. Fourteen bacteria selected for chromium reduction by Diphenyl Carbazide Assay showed 23-89% reduction. Of these 14 isolates, 5 were tested for biosorption of chromium. Variable sorption of upto 69% was observed. The 16s rDNA of 6 candidate bacteria were sequenced. These isolates were identified as Kurthia gibsonii, Acinetobacter schindleri, Pseudomonas aeruginosa, Exigubacterium sp., Rhodococcus sp., and Bacillus sp. The reduction potential was found to be highest for Bacillus species (78%) and lowest for Kurthia gibsonii (4.8%). This study has successfully identified six potential bacterial candidates for the bioremediation of chromium (VI). Further research into the mechanisms adopted by these bacteria and genetic manipulation will help to formulate a single or mixture of isolates that can efficiently remove hexavalent chromium from polluted water.
Plant Tissue Cult. & Biotech. 34(1): 71-81, 2024 (June)
Biomechanical analysis of spinal cord injury during scoliosis correction surgery
Authors: Wang Haimei , Zhang Chunyu , Wang Yongqiang , Zeng Yan , Chen Songhao , Su Xingyu , Li Weishi , Yu Miao , Chen Duanduan 
Published: July 2024

Introduction: Surgical correction is a common treatment for severe scoliosis. Due to the significant spinal deformation that occurs with this condition, spinal cord injuries during corrective surgery can occur, sometimes leading to paralysis.Methods: Such events are associated with biomechanical changes in the spinal cord during surgery, however, their underlying mechanisms are not well understood. Six patient-specific cases of scoliosis either with or without spinal complications were examined. Finite element analyses (FEA) were performed to assess the dynamic changes and stress distribution of spinal cords after surgical correction. The FEA method is a numerical technique that simplifies problem solving by replacing complex problem solving with simplified numerical computations.Results: In four patients with poor prognosis, there was a concentration of stress in the spinal cord. The predicted spinal cord injury areas in this study were consistent with the clinical manifestations of the patients. In two patients with good prognosis, the stress distribution in the spinal cord models was uniform, and they showed no abnormal clinical manifestations postoperatively.Discussion: This study identified a potential biomechanical mechanism of spinal cord injury caused by surgical correction of scoliosis. Numerical prediction of postoperative spinal cord stress distribution might improve surgical planning and avoid complications.
Utilizing nutrient type compounds as anti-bacterial compounds: arginine and cysteine inhibit Salmonella survival in egg white
Authors: Ben-Porat Nir , Ohayon Amital , Rosenberg Tali , Musa Abdulafiz , Petersen Erik , Mills Erez 
Published: July 2024

Because of growing levels of antibiotic resistance, new methods to combat bacteria are needed. We hypothesized that because bacteria evolved to survive in specific environments, the addition of compounds, including nutrient type compounds, to an environment, might result in a modification of that environment that will disrupt bacterial growth or in maladaptive bacterial behavior, i.e., gene expression. As a proof of concept, we focused on the egg white environment and the pathogen Salmonella. Despite egg white’s antibacterial nature, Salmonella is able to survive and grow in egg white, and this ability of Salmonella leads to infection of chicks and humans. Here, the 20 L-amino-acids were screened for their ability to affect the growth of Salmonella in egg white. L-arginine and L-cysteine were found to reduce growth in egg white in physiologically relevant concentrations. To determine the mechanism behind L-arginine inhibition TnSeq was utilized. TnSeq identified many Salmonella genes required for survival in egg white including genes required for iron import, biotin synthesis, stress responses, cell integrity, and DNA repair. However, a comparison of Salmonella in egg white with and without L-arginine identified only a few differences in the frequency of transposon insertions, including the possible contribution of perturbations in the cell envelope to the inhibition mechanism. Finally, both D-arginine and D-cysteine were found to inhibit Salmonella in egg white. This implied that the effect of arginine and cysteine in egg white is chemical rather than biological, likely on the egg white environment or on the bacterial outer membrane. To conclude, these results show that this approach of addition of compounds, including nutrient type compounds, to an environment can be used to limit bacterial growth. Importantly, these compounds have no inherent anti-bacterial properties, are used as nutrients by animals and bacteria, and only become anti-bacterial in a specific environmental context. Future research screening for the effects of compounds in relevant environments might uncover new ways to reduce pathogen levels in the poultry industry and beyond.
Prolonged Impella 5.0/5.5 support within different pathways of care for cardiogenic shock: the experience of a referral center
Authors: Pieri Marina , Ortalda Alessandro , Altizio Savino , Bertoglio Luca , Nardelli Pasquale , Fominskiy Evgeny , Lapenna Elisabetta , Ajello Silvia , Scandroglio Anna Mara 
Published: July 2024

AimsImpella 5.0 and 5.5 are promising low-invasive left ventricle (LV) temporary mechanical circulatory supports (tMCS) for cardiogenic shock due to LV mechanical unloading and are paired with powerful hemodynamic support. This study aimed to analyze data and destinies of patients supported with Impella 5.0/5.5 at a national referral center for cardiogenic shock and to assess the parameters associated with myocardial recovery and successful weaning.MethodsA single-center observational study was conducted on all patients treated with Impella 5.0 or 5.5 from March 2018 to July 2023.ResultsA total of 59 patients underwent Impella 5.0/5.5 implantation due to profound cardiogenic shock, with acute myocardial infarction being the most frequent cause of shock (42 patients, 71%). The median duration of Impella support was 13 days (maximum duration of 52 days). Axillary cannulation was feasible in almost all patients, and 36% were mobilized during support. A total of 44 patients (75%) survived to the next therapy/recovery: 21 patients experienced recovery and 15 and 8 were bridged to long-term LVAD and heart transplantation, respectively. The global survival rate was 66%. The predictors of native heart recovery at multivariate analysis were the number of days on tMCS before upgrade to Impella 5.0/5.5 [hazard ratio (HR) 0.68 (0.51–9) p = 0.0068] and improvement of LVEF within the first 7–10 days of support [HR 4.72 (1.34–16.7), p = 0.016].ConclusionsTranscatheter systems such as Impella 5.0/5.5 revolutionized the field of tMCS. Myocardial recovery is the primary clinical target. Its prognostication and promotion are key to ensure the most proficuous course for each patient from cardiogenic shock to long-term event-free survival.
Changes in body weight and composition, metabolic parameters, and quality of life in patients with type 2 diabetes treated with subcutaneous semaglutide in real-world clinical practice
Authors: Pantanetti Paola , Cangelosi Giovanni , Alberti Sara , Di Marco Sandra , Michetti Grazia , Cerasoli Gianluca , Di Giacinti Marco , Coacci Silvia , Francucci Nadia , Petrelli Fabio , Ambrosio Giuseppe , Grinta Roberto 
Published: July 2024

Subcutaneous once-weekly (ow) semaglutide is a recent treatment option for type 2 diabetes (T2D) and obesity, but real-world data on weight loss and associated changes in body composition, nutrients intake, and quality of life are still scarce. This observational, prospective clinical study involved all T2D patients starting ow semaglutide according to routine care between December 2021 and February 2022. Clinical information was collected after 6 months (T6) and 12 months (T12) from semaglutide initiation (T0). Bioelectrical Impedance Analysis (BIA) was performed to measure changes in body composition. Diabetes Treatment Satisfaction Questionnaire (DTSQ) and the 36 – items Short Form Health Survey (SF-36) were administered as patient-reported outcomes (PROs). Changes in continuous endpoints (weight, body composition, nutrients intake, other clinical parameters, and PROs) were assessed using mixed models for repeated measurements. Overall, 90 patients (age 63.0 ± 10.0 years; diabetes duration 7.6 ± 5.9 years; 58.9% men; HbA1c 7.7 ± 1.1%; weight 95.4 ± 19.4 Kg, BMI 34.6 ± 6.4 Kg/m2; 36.7% naïve to diabetes treatment, 43.3% on metformin, 10.0% on dual oral therapy, and 10.0% treated with schemes including insulin) were included in the study. After 6 months from semaglutide initiation, body weight significantly decrease by -4.69 Kg (95%CI -6.19;-3.19) (primary endpoint). After 12 months, body weight was further reduced (-5.38 Kg; 95%CI -7.79;-2.97). At BIA, fat mass was significantly reduced by 2.1 Kg after 6 months but only slightly reduced after 12 months vs. baseline; lean mass was also significantly reduced by over 3 Kg both at 6 and 12 months. Intake of all nutrients declined in the first 6 months of therapy, although only lipids reduction reached the statistical significance (-6.73 g; p=0.02). Statistically significant improvements in BMI, waist circumference, glycemic control, blood pressure and lipid profile were documented. Satisfaction with treatment (DTSQ questionnaire) and mental health (MCS score of SF-36 questionnaire) significantly increased during the follow-up. The study documented real-world benefits of semaglutide for treating obesity in T2D subjects, with important changes on clinical and patient-reported outcomes. Loss of lean mass associated with weight loss warrants attention; parallel strategies to preserve skeletal muscle and improve physical function, i.e. nutritional education and structured exercise, are of great importance.
Tele-rehabilitation for Type II diabetics with heart failure with preserved ejection fraction
Authors: Yuan Minjie , Xu Haimin , Zhao Dongqi , Shi Dongdong , Su Li , Zhu Huifang , Lu Shengdi , Wei Junbo 
Published: July 2024

ObjectiveThis study aims to determine whether tele-rehabilitation has similar effects to conventional face-to-face physical rehabilitation for diabetic patients with heart failure with preserved ejection fraction (HFpEF).Materials and methodsDemographic, laboratory, diagnostic and rehabilitation information for patients with type 2 diabetes with HFpEF were extracted from disease-specific databases. Outcome measures, including the Short Physical Performance Battery (SPPB), 6-minute walk distance, frailty status, European Quality of Life 5-Dimension 5-Level questionnaire (EQ-5D-5L) and reduction in HbA1c from admission, patients who received tele-rehabilitation therapy were compared to those received face-to-face rehabilitation.ResultsIn this study, 90 patients with type 2 diabetes and HFpEF using tele-rehabilitation were matched with 90 patients with type 2 diabetes and HFpEF using face-to-face physical rehabilitation. Improvements in the results of the SPPB scores, 6-min walk distance and gait speed and EQ-5D-5L were noted from the follow-up time point 3 months to 6 months in both two groups. There were no significant differences in functional tests and quality of life between the two groups.ConclusionOur study proved that mobile-based tele-rehabilitation programs are non-inferior to face-to-face physical rehabilitation for diabetes patients after HFpEF. In addition, adherence to the telerehabilitation program showed that the novel technology was accepted well and could be an alternative to the conventional face-to-face rehabilitation program.
Time-varying effect in older patients with early-stage breast cancer: a model considering the competing risks based on a time scale
Authors: Yu Zhiyin , Geng Xiang , Li Zhaojin , Zhang Chengfeng , Hou Yawen , Zhou Derun , Chen Zheng 
Published: July 2024

BackgroundPatients with early-stage breast cancer may have a higher risk of dying from other diseases, making a competing risks model more appropriate. Considering subdistribution hazard ratio, which is used often, limited to model assumptions and clinical interpretation, we aimed to quantify the effects of prognostic factors by an absolute indicator, the difference in restricted mean time lost (RMTL), which is more intuitive. Additionally, prognostic factors of breast cancer may have dynamic effects (time-varying effects) in long-term follow-up. However, existing competing risks regression models only provide a static view of covariate effects, leading to a distorted assessment of the prognostic factor.MethodsTo address this issue, we proposed a dynamic effect RMTL regression that can explore the between-group cumulative difference in mean life lost over a period of time and obtain the real-time effect by the speed of accumulation, as well as personalized predictions on a time scale.ResultsA simulation validated the accuracy of the coefficient estimates in the proposed regression. Applying this model to an older early-stage breast cancer cohort, it was found that 1) the protective effects of positive estrogen receptor and chemotherapy decreased over time; 2) the protective effect of breast-conserving surgery increased over time; and 3) the deleterious effects of stage T2, stage N2, and histologic grade II cancer increased over time. Moreover, from the view of prediction, the mean C-index in external validation reached 0.78.ConclusionDynamic effect RMTL regression can analyze both dynamic cumulative effects and real-time effects of covariates, providing a more comprehensive prognosis and better prediction when competing risks exist.