bluuebunny/crossref_metadata_2025_split huggingface dataset:
Management and outcome of patients supported with Impella 5.0 for refractory cardiogenic shock
Authors: Gaudard Philippe , Mourad Marc , Eliet Jacob , Zeroual Norddine , Culas Geraldine , Rouvière Philippe , Albat Bernard , Colson Pascal 
Published: October 2015

AbstractIntroductionCardiogenic shock refractory to standard therapy with inotropes and/or intra-aortic balloon pump is accompanied with an unacceptable high mortality. Percutaneous left ventricular assist devices may provide a survival benefit for these very sick patients. In this study, we describe our experience with the Impella 5.0 device used in the setting of refractory cardiogenic shock.MethodsIn this observational, retrospective, single-center study we included all the consecutive patients supported with Impella 5.0, between May 2008 and December 2013, for refractory cardiogenic shock. Patients’ baseline and procedural characteristics, hemodynamics and outcome to the first 48 h of support, to ICU discharge and day-28 visit were collected.ResultsA total of 40 patients were included in the study. Median age was 57 years and 87.5 % were male. Cardiogenic shock resulted from acute myocardial infarction in 17 patients (43 %), dilated cardiomyopathy in 12 (30 %) and postcardiotomy cardiac failure in 7 (18 %). In 15 patients Impella 5.0 was added to an ECMO to unload the left ventricle. The median SOFA score for the entire cohort prior to circulatory support was 12 [10–14] and the duration of Impella support was 7 [5–10] days. We observed a significant decrease of the inotrope score (10 [1–17] vs. 1 [0–9];p = 0.04) and the lactate values (3.8 [1.7–5.9] mmol/L vs. 2.5 [1.5–3.4] mmol/L;p = 0.01) after 6 h of support with Impella 5.0. Furthermore, at Impella removal the patients’ left ventricular ejection fraction improved significantly (p < 0.001) when compared to baseline. Cardiac recovery, bridge to left ventricular assist device or heart transplantation was possible in 28 patients (70 %). Twenty-six patients (65 %) survived at day 28. A multivariate analysis showed a higher risk of mortality for patients with acute myocardial infarction (hazard ratio = 4.1 (1.2–14.2);p = 0.02).ConclusionsImpella 5.0 allowed fast weaning of inotropes and might facilitate myocardial recovery. Despite high severity scores at admission, day-28 mortality rate was better than predicated.
CREATIVITY AS A SUCCESS FACTOR IN PROMOTIONAL ASPECT OF PRODUCTS IN PRODUCTION COMPANIES
Authors: Arapi Rajan 
Published: October 2015

The creativity, as a general concept, is considered an activity which gives birth to something new that did not exist before. This topic can be affected also from the philosophical and physiological point of view. The psychology of creativity studies “Psychological Mechanism” from which stem the actions of creativity.In promotion terms there are different points of views that are considered to be an integral part of creativity in the field of product advertising. First, there are people who estimate if the promotion is creative whereas on the other side the effect only in cases where you succeeded to sell the product. Second, there are people who consider their creativity or design of the promotion as their originality artistic or esthetical value.What constitutes the creativity in one of the elements of the promotion is distinguishing and entertaining idea of being different from the others, but the creative message must be short and clear. Advertisements or promotional campaigns that are creative rarely fail to transmit their message to the public consumer. In this case, the entire team that is engaged in planning and developing the promotional campaign must balance their attitudes around the creative idea.This research presents the development of ideas and designs of creative promotional spaces for Kosovar companies in cases of the advertisement of their new and existing products in the market. The methodology of this research will be descriptive and comparative between a few manufacturing Kosovar companies.
QUALITY OF LIFE COMPARISON OF PEOPLE WITH AND WITHOUT DIABETES MELLITUS
Authors: Živčicová Eva , Gullerová Monika 
Published: October 2015

Quality of life is distinctly conceived as a construct, and, therefore, is distinctly defined and measured. The main purpose of this article was to compare the quality of life assessment in respondents with and without diabetes mellitus by using World Health Organization Quality of Life Assessment (WHOQOL-BREF) questionnaire. Then, quality of life in several major domains, such as physical health, psychological domain, social relationships, and environment is assessed and compared. Finally, a quality of life profile in respondents with and without diabetes mellitus in the Czech and Slovak Republic is produced and compared.
THE PROTECTION OF INVESTORS’ RIGHTS IN KAZAKHSTAN
Authors: Shegirbayeva Madina , Shegirbayev Ozhet 
Published: October 2015

Since obtaining independence, the Republic of Kazakhstan has developed an ‘open-door’ policy for foreign investors ready to invest in the country's economy. Over time, approaches and mechanisms that have created favorable conditions for investors have changed, along with appropriate amendments to the legislation. Currently, Kazakhstan is a rapidly developing country with great potential. According to the World Bank, out of 189 countries, Kazakhstan rated 50th in 2014 for ‘Doing Business’. Nonetheless, many foreign investors may rightly query about the guarantees for protecting investors' rights in this country, under the conditions they find here. This article aims to cover the mechanisms for protecting the investors' rights in the Republic of Kazakhstan, taking into account the recent changes in investment law, and based on a several case reviews.
Achieving a holistic perspective in stroke rehabilitation: An overview of the use of the ICF by Danish physiotherapists and occupational therapists
Authors: Kristensen Hanne K , Lund Hans , Jones Dorrie L , Ytterberg Charlotte 
Published: October 2015

Background/Aims: Holistic, multidisciplinary rehabilitation is often the most appropriate for stroke patients. The World Health Organization's International Classification of Functioning, Disability and Health (ICF) provides a comprehensive conceptual framework and systematic terminology used by health professionals worldwide. The purpose of this study was to explore how the components of the ICF were addressed by physiotherapists and occupational therapists in stroke rehabilitation. Methods: A prospective cohort study, including all service levels within Danish stroke rehabilitation, was carried out. Consecutive patients with a diagnosis of stroke (n=131; 70 males and 61 females; mean age: 72 years) admitted to a university hospital between May and December 2012 were enrolled by 13 physiotherapists and occupational therapists. Physiotherapist and occupational therapist documentation was collected from participants' medical records and analysed using deductive content analysis until saturation was reached. Data were generated in four settings that encompass the general Danish health care service to adult stroke patients in hospitals and community-based settings. Results: Patient data were documented according to three of the ICF components, i.e. body functions and structures, activity and participation, and environmental factors. No distinct pattern emerged that would enable a differentiation between therapists' notes in the four settings. Conclusions: The ICF framework may contribute to a holistic approach in stroke rehabilitation, including an understanding of functioning and the ability to participate in everyday life. Using this approach to rehabilitation, disability is not only perceived as a consequence of stroke but also in the context of the individual person, where interactions between the biological, psychological, social and environmental aspects must be taken into account in order to provide an adequate rehabilitation service. Nevertheless, more attention seems to be paid to health components at the expense of the contextual factors; this needs to be addressed to augment the holistic approach.
Saints and sinners: Lessons about work from daytime TV
Authors: Huws Ursula 
Published: October 2015

Abstract
This article looks at the messages given by factual TV programmes to audiences about work, and, in particular, the models of working behaviour that have been presented to them during the period following the 2007–2008 financial crisis. It focuses particularly, but not exclusively, on daytime TV, which has an audience made up disproportionately of people who have low incomes and are poorly educated: an audience that, it can be argued, is not only more likely than average to be dependent on welfare benefits and vulnerable to their withdrawal but also more likely to be coerced into entering low-paid insecure and casual employment.
It argues that the messages cumulatively given by ‘factual’ TV, including reality TV programmes ostensibly produced for entertainment, as well as documentaries, combine to produce a particular neo-liberal model of the deserving worker (counterposed to the undeserving ‘scrounger’ or ‘slacker’) highly suited to the atomized and precarious labour markets of a globalized economy. This is, however, a model in which there are considerable tensions between different forms of desired behaviour: on the one hand, a requirement for intense, individualized and ruthless competitiveness and, on the other, a requirement for unquestioning and self-sacrificing loyalty and commitment to the employer and the customer. These apparently contradictory values are, however, synthesized in a rejection, often amounting to demonization, of collective values of fairness, entitlement and solidarity.
A bridge too far? Analysis of the European Commission’s new developments on media policy and media freedoms through the concept of soft regulation
Authors: Costache Andreea M. , Llorens Carles 
Published: October 2015

Abstract
This article tries to examine the latest European Commission (EC) policy developments in the media sector through the new concept of soft regulation. Much criticized for its media policy approaches, the EC seems to try to rebuild media freedom and media pluralism protection foundations at the EU level with several new initiatives based on soft regulation. This article analyses these soft-regulatory media policy actions to answer the following questions: Have soft-regulatory measures been a good option to improve media pluralism policy at the EU level? Are there better mechanisms that EU can employ to assist Member States in promoting media pluralism? The aim of the research is to see whether these new EC debates and softregulatory initiatives have made a real change in the traditional way that EC has been dealing with audio-visual matters or whether it is only repeating old answers to old questions.
Book Reviews
Authors: Violi Patrizia , Goodmann Emily , Dines Mike 
Published: October 2015

Abstract
The Labour of Memory: Memorial Cult ure and 7/7, Matthew Allen (2014) 1st ed., London: Palgrave Macmillan, 176 pp., ISBN: 9781137341631, h/bk, $95.00
The Undersea Network, Nicole Starosielski (2015) 1st ed., Durham, NC: Duke University Press, 312 pp., ISBN: 9780822357551, p/bk, $25.95
Fight Back: Punk, Politics and Resistance, The Subcultures Network (ed.) (2014) 1st ed., Manchester: Manchester University Press, 320 pp., ISBN: 9780719090295, h/bk, £75.00
Computational modelling and digital materialization of Alberti’s column system: a reflection on results obtained
Authors: Castro e Costa Eduardo 
Published: October 2015

We hereby focus the study of the Albertian column system, as part of the Digital Alberti project, a research initiative that aims to shed some light on the influence of Alberti on Portuguese architecture. Starting from Alberti’s treatise on architecture, De Re Aedificatoria, and its translation into Portuguese, Da Arte Edificatória, a generative computational model was developed that encodes Alberti’s prescriptions about the elements of the column system, as well as their proportions and shapes. This research complements the elaboration of the corresponding shape grammar on Alberti’s column system. This project is a paradigmatic example of the use of digital technology for understanding architectural tradition. The development of the referred models implied deepening the understanding of Alberti’s rules about the column elements. This in-depth analysis revealed a very coherent hierarchical structure ruling the relationships among the several elements. It also revealed that information was insufficient to inform a formal model of all them, especially the ones showing more complex geometry, such as the corinthian and composite capitals. Therefore, it can be considered that the application of digital technologies allowed to more accurately understand and reproduce Alberti’s guidelines for the art of building. Foca-se o estudo do sistema de coluna Albertiano, no âmbito do projecto Alberti Digital, cuja investigação pretende elucidar sobre a influência de Alberti na arquitetura portuguesa. Partindo do tratado de Alberti sobre arquitetura, De re aedificatoria, e da sua tradução para português, Da Arte Edificatória, foi desenvolvido um modelo computacional generativo que codifica as instruções de Alberti respeitantes aos elementos do sistema de coluna, bem como as suas proporções e formas. A investigação complementa a elaboração da gramática da forma correspondente ao sistema de coluna Albertiano. O projecto é um exemplo paradigmático do uso de tecnologias digitais na compreensão da tradição arquitetónica. O desenvolvimento dos modelos referidos implicou um entendimento aprofundado das regras de Alberti sobre os elementos da coluna. Esta análise revelou uma estrutura hierárquica consistente que rege as relações entre os diversos elementos. Revelou também que, para uma modelação exacta de todos esses elementos, a informação fornecida por Alberti não é suficiente, nomeadamente nos casos mais complexos dos capitéis coríntio e compósito. Considera-se assim que a aplicação de tecnologias digitais permitiram compreender e reproduzir mais exactamente as orientações de Alberti para a arte da construção.
Computational modelling and digital materialization of Alberti’s column system: a reflection on results obtained
Authors: Castro e Costa Eduardo , Duarte José P. , Kruger Mário 
Published: October 2015

We hereby focus the study of the Albertian column system, as part of the Digital Alberti project, a research initiative that aims to shed some light on the influence of Alberti on Portuguese architecture. Starting from Alberti’s treatise on architecture, De Re Aedificatoria, and its translation into Portuguese, Da Arte Edificatória, a generative computational model was developed that encodes Alberti’s prescriptions about the elements of the column system, as well as their proportions and shapes. This research complements the elaboration of the corresponding shape grammar on Alberti’s column system. This project is a paradigmatic example of the use of digital technology for understanding architectural tradition. The development of the referred models implied deepening the understanding of Alberti’s rules about the column elements. This in-depth analysis revealed a very coherent hierarchical structure ruling the relationships among the several elements. It also revealed that information was insufficient to inform a formal model of all them, especially the ones showing more complex geometry, such as the corinthian and composite capitals. Therefore, it can be considered that the application of digital technologies allowed to more accurately understand and reproduce Alberti’s guidelines for the art of building.Foca-se o estudo do sistema de coluna Albertiano, no âmbito do projecto Alberti Digital, cuja investigação pretende elucidar sobre a influência de Alberti na arquitetura portuguesa. Partindo do tratado de Alberti sobre arquitetura, De re aedificatoria, e da sua tradução para português, Da Arte Edificatória, foi desenvolvido um modelo computacional generativo que codifica as instruções de Alberti respeitantes aos elementos do sistema de coluna, bem como as suas proporções e formas. A investigação complementa a elaboração da gramática da forma correspondente ao sistema de coluna Albertiano. O projecto é um exemplo paradigmático do uso de tecnologias digitais na compreensão da tradição arquitetónica. O desenvolvimento dos modelos referidos implicou um entendimento aprofundado das regras de Alberti sobre os elementos da coluna. Esta análise revelou uma estrutura hierárquica consistente que rege as relações entre os diversos elementos. Revelou também que, para uma modelação exacta de todos esses elementos, a informação fornecida por Alberti não é suficiente, nomeadamente nos casos mais complexos dos capitéis coríntio e compósito. Considera-se assim que a aplicação de tecnologias digitais permitiram compreender e reproduzir mais exactamente as orientações de Alberti para a arte da construção.
Apropos Digital Alberti and Palladio Virtuel. The preponderance of tools for research in history of architecture
Authors: Gil Bruno 
Published: October 2015

[EN]
Engaging architecture with research continues to be an issue of concern among most schools of architecture, mainly when addressing the way in how design can be translated into and be considered research. Innovative tools imported from the computational universe to the realm of design have caused diverse transformations within the methodologies and ultimately continue to transform aesthetical conceptions, while investigate form and search for disruptive solutions.
Likewise it is also crucial to study how these tools are changing the actual processes of research within the investigation of history of architecture, and to assess the preponderance of these instruments for the production of theory. Hence, this paper will focus on two current research projects – Digital Alberti and Palladio Virtuel – which share the return to the Renaissance and also the use of computational tools to enhance research, even if with different objectives, methods and ends.

[PT]
Relacionar arquitectura e investigação continua a ser uma preocupação latente em grande parte das escolas de arquitectura, principalmente, em como o projecto pode ser considerado e ser traduzido em investigação. Novas ferramentas trazidas do mundo computacional para o projecto causaram diversas transformações nas metodologias e em última instância continuam a transformar as concepções estéticas, enquanto investigam a forma e procuram soluções disruptivas.
O presente artigo procura reconhecer como estas ferramentas estão a mudar os processos actuais de investigação no âmbito da história da arquitectura e avaliar a preponderância dos instrumentos para a produção de teoria. Assim, incidir-se-á em dois projectos de investigação em desenvolvimento – Alberti Digital e Palladio Virtuel – que partilham o regresso ao Renascimento e também o uso de ferramentas da computação para potenciar a investigação, se bem que com diferentes objectivos, métodos e fins.
Polymorphism of gene UBE2E2 and the risk of developing diabetes type 2
Authors: Kazakova Elena Vladimirovna , Wu Yanhui , Chen Meijun , Wang Tongtong , Sun Lulu , Qiao Hong 
Published: October 2015

Recently, the ubiquitin–proteasome pathway has emerged as a crucial pathway for protein turnover, and it has also been identified as an important factor for insulin synthesis. This pathway plays a critical role inside β cells; therefore, it has naturally been linked with various insulin-related diseases, most notably type 2 diabetes mellitus (T2DM), but also other metabolic diseases and symptoms such as obesity and atherosclerotic plaques. The UBE2E2 gene encodes ubiquitin-conjugating enzyme E2 E2 (UBE2E2), which plays an important role in the synthesis and secretion of insulin. UBE2E2 is a protein expressed in the pancreas, liver, and adipose tissue, as well as in an insulin-secreting cell line . The results of some studies have indicated that single nucleotide polymorphisms on UBE2E2 (rs6780569, rs7612463, rs9812056) are associated with T2DM risk in Japanese, Korean and Chinese populations. Therefore, the UBE2E2 gene has started to draw interest from researchers because of its newly discovered relationships with various diseases.
Qualitätsmanagement in Öffentlichen Bibliotheken
Authors: Sprung Norbert 
Published: October 2015

Zusammenfassung:
Bibliotheken stehen vor vielen Herausforderungen, denen eine stetig wachsende Zahl von Bibliotheken mit einem strategischen Management und einer kundenorientierten Verbesserung ihrer Dienstleistungen entgegenwirken wollen. In diesem Zusammenhang beschäftigt man sich im deutschen Bibliothekswesen seit 20 Jahren mit dem Thema Qualitätsmanagement. Inzwischen sind viele Projekte entstanden, in denen unterschiedliche Qualitätsmanagement-Modelle zur Anwendung kommen. Die Betrachtung dieser Modelle und der Projekte soll Aufschluss darüber geben, welches Modell sich für die Bibliotheken als zukunftsweisend gezeigt hat und sich besonders für eine bestimmte Bibliotheksart und -größe eignet.
Von der Bibliothek zum Lernort – Ganzheitliche Konzepte für studentische Lernräume
Authors: Wittenauer Volker , Neumann Marlene 
Published: October 2015

Zusammenfassung:
Bibliotheken als intensiv genutzte Lernorte stehen heutzutage vor besonderen Herausforderungen. Um Studierende ganzheitlich in ihrem Lernen und Arbeiten zu unterstützen, sind Konzepte notwendig, die traditionelle bibliothekarische Kernkompetenzen mit innovativen Services verknüpfen. Die Badische Landesbibliothek richtet ihr Service-Portfolio seit einigen Jahren gezielt an den Bedürfnissen studentischer Nutzer aus. Sie bietet ein breit gefächertes Angebot, das sowohl räumliche als auch soziale Komponenten der Lernortgestaltung berücksichtigt.
The perception of Mandarin lexical tones by listeners from different linguistic backgrounds
Authors: Tsukada Kimiko , Xu Hui Ling , Rattanasone Nan Xu 
Published: October 2015

Abstract
Two groups of non-native adult learners of Mandarin in Australia were directly compared in their ability to perceive monosyllabic Mandarin words contrasting in lexical tones. They differed in their linguistic experience (non-heritage (n=10), heritage (n=12)). A group of eight native Mandarin speakers and a group of ten functionally monolingual speakers of Australian English were included as controls. All non-native learners used English as their primary language of communication. However, the heritage learners were able to communicate in Cantonese as well as English. The primary question of interest was whether heritage learners’ knowledge of contrastive tone in Cantonese might give them an advantage over English-speaking learners in perceiving tone contrasts in Mandarin. In general, there were more similarities than differences between the two groups of learners in their response patterns. Of the six tone contrasts examined (T1-T2, T1-T3, T1-T4, T2-T3, T2-T4, T3-T4), the two groups significantly differed only on T1-T4. The heritage learners were less accurate on T1-T4 than the non-heritage learners who are monolingual speakers of Australian English. On the other hand, the non-heritage learners were more accurate than Australian English speakers with no prior experience with Mandarin on all tone contrasts. Thus, we conclude that simply having an exposure to and functional knowledge of another tonal language since early childhood does not guarantee accurate perception of Mandarin tones in comparison with adult learners without prior experience with tonal languages.