bluuebunny/crossref_metadata_2025_split huggingface dataset:
Researchers' green open access practice: a cross‐disciplinary analysis
Authors: Spezi Valérie , Fry Jenny , Creaser Claire , Probets Steve , White Sonya 
Published: May 2013

PurposeThis paper aims to report on the findings of the second phase of the Behavioural strand of the EC‐funded PEER project (http://www.peerproject.eu/). The paper seeks to explore authors' and readers' behaviours in relation to authors' peer‐reviewed accepted manuscripts in open access repositories.Design/methodology/approachThe research was undertaken using a mixed‐method approach, involving the distribution of a survey by the 12 participating publishers to their authors in selected journal titles and a participatory workshop with European researchers from selected disciplinary areas.FindingsResearchers' attitudes towards versions of published journal articles made open access via open access repositories may vary depending on whether researchers report behaviours from the perspective of an author or a reader. The research found that disciplinary cultures, norms and traditions shape authors' self‐archiving behaviour and readers' use of those versions of journal articles held in repositories.Research limitations/implicationsOne of the limitations of the research is that it was impossible for the research team to gauge the representativeness of the survey compared to the actual disciplinary distribution of the population of EU researchers, as such population information is not available in an aggregated and consistent format.Originality/valueThe PEER Observatory is an unprecedented large‐scale collaboration between publishers, researchers and repositories to investigate the effects of self‐archiving at European level. The paper provides a disciplinary reading of the findings and augments the understanding of how disciplinary culture and norms shape authors' and readers' behaviours in relation to self‐archiving.
Report of the Editor‐in‐Chief
Authors: Harvey David 
Published: May 2013

AbstractSubmissions to the Journal continue to increase, with a strong international pattern, while our response times are also improving. The JAE's citation impact factor reached a record high in 2011 at 1.55, with data on 2012 citations suggesting a modest decline in 2012 (due to be published in June 2013). Wiley‐Blackwell continues to provide a strong publishing platform with our full archive generating rapidly increasing numbers of downloads.
Comparison of blind and electrically guided tracheal needle insertion in human cadavers
Authors: Tsui B. C. , Neufeld A. , Walji A. H. 
Published: May 2013

SummaryThe purpose of this study was to investigate whether an electrically guided needle insertion technique would enable greater success at intratracheal needle tip insertion than the traditional, aspiration‐of‐air technique. Twenty‐seven anaesthesiology residents were assessed in their ability to place a needle tip in the trachea of cadavers using the two methods. Success of needle placement, time to placement and confidence in placement were recorded. Correct intratracheal needle placement was achieved by 22% of residents (6/27) using the aspiration‐of‐air method vs 82% (22/27) using the electrically guided method (p < 0.001). For the instances of success, there was no significant difference between the two methods in the median (IQR [range]) time taken (28 (24–49 [18–63]) s aspiration vs 32 (19–49 [15–84]) s electrical; p = 0.93). The electrically guided method provides an acceptably quick and accurate way of placing a needle tip into the tracheal lumen and can be learnt easily by anaesthesiology residents.
Copy number aberrations using multicolour fluorescence in situ hybridization (FISH) for prognostication in non‐muscle‐invasive bladder cancer (NIMBC)
Authors: Matsuyama Hideyasu , Ikemoto Kenzo , Eguchi Satoshi , Oga Atsunori , Kawauchi Shigeto , Yamamoto Yoshiaki , Kawai Yoshihisa , Matsumoto Hiroaki , Hara Takahiko , Nagao Kazuhiro , Sakano Shigeru , Sasaki Kohsuke 
Published: May 2013

Objective
To investigate if detection of copy number aberrations of chromosomes 3, 7, 9p21, and 17 using multicolour fluorescence in situ hybridization (FISH) predicts patient outcome in non‐muscle‐invasive bladder cancer (NMIBC).
Patients and Methods
In all, 118 bladder wash samples were prospectively collected from patients who underwent transurethral resection of bladder tumour (median age 50.5 years, male/female: 91/27, tumour grade 1/2/3: 18/52/42, stage pTis/Ta/T1: 8/62/42) from 2007 to 2010.
The 118 samples were analysed using the UroVysion® kit to detect the copy numbers of chromosomes 3, 7, 9p21, and 17.
The variant fraction (VF; the sum of the non‐modal copy number fraction of each chromosome) was defined as abnormal when the percentage was ≥16%. The percentage deletion of 9p21 (fraction of null or one copy number of the 9p21 locus) was defined as abnormal when the percentage was ≥12%.
Maffezzini risk criteria were also analysed in our cohorts.
Results
There was recurrence in 57 (48.3%) patients and disease progression in 12 (10.1%), with a median follow‐up of 35.7 months.
Multivariate analysis showed that the percentage 9p21 loss (>12%) was an independent prognostic factor for recurrence (P < 0.001, odds ratio [OR] 3.24, 95% confidence interval [CI] 1.85–5.62).
For disease progression, tumour grade, positive urine cytology, concurrent carcinoma in situ, and a mean VF of >16% were significant prognostic factors in univariate analysis. In multivariate analysis, a mean VF of >16% was a prognostic factor for disease progression (P = 0.048, OR 6.07, 95% CI 1.02–57.45).
Conclusions
Multicolour‐FISH analysis using a commercially available kit could be a powerful tool not only for diagnosis, but also for prognostication in patients with NMIBC.
Spatiotemporal patterns of the Huntingtin‐interacting protein 1‐related gene in the mouse head
Authors: Masuda Tomoyuki , Sakuma Chie , Ueno Takayuki , Yamada Yuriko , Ohmomo Hideki , Ueda Shuichi , Yamagishi Toshiyuki , Yaginuma Hiroyuki 
Published: May 2013

AbstractHuntingtin‐interacting protein 1‐related (Hip1r) was originally identified due to its homology to Huntingtin‐interacting protein 1, which contributes to the development of Huntington's disease (HD). We studied the expression of the mouse Hip1r (mHip1r) gene in the mouse head by in situ hybridization. In early embryogenesis at embryonic day (E) 13, mHip1r expression was especially prominent in the olfactory epithelium, cerebral cortex layer 1, cortical plate, and dentate gyrus. During later development from E15 to E17, strong expression of mHip1r transcripts continued to be observed in the olfactory epithelium, cortical plate, and dentate gyrus. Furthermore, not only the subplate and subventricular zone of the cortex, but also secretory glands, such as the nasal gland and the submandibular gland, were mHip1r‐positive. Other positive tissues included the retinal ganglion cells, vomeronasal organ, trigeminal ganglion, and the developing molar tooth. In the adult mouse brain, similar expression patterns were observed in the cerebral cortex layers and other brain regions except the cerebellum. Additionally, by using an antibody against mHip1r, we confirmed these expression patterns at the protein level. Specific expression of mHip1r in the embryonic brain and secretory glands suggests a possible role for Hip1r in normal development and in the pathology of HD.
Vertical rectus abdominis myocutaneous flap reconstruction of the perineal defect after abdominoperineal excision is associated with low morbidity
Authors: Barker T. , Branagan G. , Wright E. , Crick A. , McGuiness C. , Chave H. 
Published: May 2013

AbstractAimTo examine the short‐term outcomes of perineal reconstruction with a vertical rectus abdominis myocutaneous (VRAM) flap following abdominoperineal excision (APE).MethodRetrospective case note review of all patients undergoing APE and primary VRAM reconstruction between July 2001 and February 2012 in a district general hospital tertiary referral centre for APE. Complications were categorized using the Clavien–Dindo classification, which grades complications from I to V in order of increasing severity.ResultsFifty‐five consecutive patients (31 men, median age 65, range 38–84 years) underwent APE with VRAM flap reconstruction, 15 for anal cancer and 40 for rectal cancer. Median length of stay was 11 days but was significantly shorter in the laparoscopic group compared with the open group (8 vs 12 days; P < 0.01) and in patients who did not experience any complications (P < 0.05). Four patients (7%) had major complications (Grade 3 and above) directly related to the flap or donor site.ConclusionVRAM reconstruction of the perineum can be safely performed following APE with results that compare favourably with other techniques. Most flap complications are minor, although these are still associated with an increase in the length of hospital stay.
Effects of serum reduction and VEGF supplementation on angiogenic potential of human adipose stromal cells in vitro
Authors: Chua K. H. , Raduan F. , Wan Safwani W. K. Z. , Manzor N. F. M. , Pingguan‐Murphy B. , Sathapan S. 
Published: May 2013

AbstractObjectivesThis study investigated effects of reduced serum condition and vascular endothelial growth factor (VEGF) on angiogenic potential of adipose stromal cells (ASCs) in vitro.Materials and methodsAdipose stromal cells were cultured in three different types of medium: (i) F12/DMEM (FD) supplemented with 10% FBS from passage 0 (P0) to P6; (ii) FD supplemented with 2% FBS at P6; and (iii) FD supplemented with 2% FBS plus 50 ng/ml of VEGF at P6. Morphological changes and growth rate of ASCs were recorded. Changes in stemness, angiogenic and endogenic genes’ expressions were analysed using Real‐Time PCR.ResultsAdipose stromal cells changed from fibroblast‐like shape when cultured in 10% FBS medium to polygonal when cultured in 2% FBS plus VEGF‐supplemented medium. Their growth rate was lower in 2% FBS medium, but increased with addition of VEGF. Real‐Time PCR showed that ASCs maintained most of their stemness and angiogenic genes’ expression in 10% FBS at P1, P5 and P6, but this increased significantly in 2% FBS at P6. Endogenic genes expression such as PECAM‐1, VE chaderin and VEGFR‐2 decreased after serial passage in 10% FBS, but increased significantly at P6 in 2% FBS. Addition of VEGF did not cause any significant change in gene expression level.ConclusionAdipose stromal cells had greater angiogenic potential when cultured in reduced serum conditions. VEGF did not enhance their angiogenic potential in 2% FBS‐supplemented medium.
In Praise of Organization: Egypt between Activism and Revolution
Authors: Abdelrahman Maha 
Published: May 2013

ABSTRACTThis article considers the nature of activism and revolutionary process in the twenty‐first century by examining some of the dilemmas involved in Egypt's ongoing process of transformation. Over the course of only a couple of weeks Egyptian activists who, for over a decade, had protested against Mubarak and his neoliberal policies, found themselves transformed from protestors, demonstrators and strikers, members of loosely structured networks, to the status of ‘revolutionaries’. These newly‐minted revolutionaries were suddenly expected either to capture or renegotiate state power, provide a vision for the future emanating from the iconic image of Tahrir Square and transform both polity and society. The article argues that the characteristics of New Social Movements (NSMs), especially the absence of sustainable organizational structures, although well suited to the phase of mass protests in the lead‐up to the ousting of Mubarak, now pose one of the main challenges to the prospects of genuine revolutionary change in the post‐Mubarak era.
Transnational Feminist Engagement with 2010+ Activisms
Authors: Harcourt Wendy 
Published: May 2013

ABSTRACTThis contribution reflects on the changes happening as transnational feminist movements engage in the shifting global dynamics and new forms of civil action that are changing the way movements operate post‐2010. The focus of the article is on the transformation of an international women's rights network, the Association for Women's Rights in Development (AWID). In particular, the author analyses the triennial AWID Forums as spaces in which feminists interrogate current social, economic and political changes. In a self‐reflective examination of this particular feminist process, the author argues that AWID is an evolving blend of old and new civic action — on the one hand, keeping continuity with the values and principles of feminism, while at the same time disconnecting in its activities with old forms of organizing and mobilizing. Through this blend of old and new, AWID opens spaces particularly for young women to reconfigure power relations within and outside feminist movements as part of the post‐2010 activisms.
Functional diversity decreases with temperature in high elevation ant fauna
Authors: REYMOND ALAIN , PURCELL JESSICA , CHERIX DANIEL , GUISAN ANTOINE , PELLISSIER LOÏC 
Published: May 2013

Severe environmental conditions filter community species compositions, forming clines of functional diversity along environmental gradients. Here, the changes in functional diversity in ant assemblages with severe environmental conditions in the Swiss Alps were investigated.
Eight sites were sampled along an elevation gradient (1800–2550 m). The variation in functional diversity was analysed along an elevation gradient considering four traits: social structure (monogynous vs. polygynous), worker size, pupal development, and nest structure.
Ant species richness and functional diversity decreased with decreasing temperature. Species found in colder habitats tended to live in subterranean nests rather than in mounds and exhibit a polymorphism in queen number, either within or across populations. The phylogenetic diversity did not decrease at colder temperature: Formicinae and Myrmicinae occupied the full range of elevations investigated.
An insulation experiment indicated that mounds are more thermally insulated against the cold compared with soil. The absence of a mound‐building ant from high elevations probably results from a reduction in the amount of vegetal materials provided by coniferous trees.
More severe abiotic conditions at higher elevations act as a filter on ant assemblages, directly through physiological tolerances to the abiotic conditions and indirectly as the vegetation necessary for nest building shifts with elevation.
Soil and vegetation features determine the nested pattern of ant–plant networks in a tropical rainforest
Authors: DÁTTILO WESLEY , RICO‐GRAY VÍCTOR , RODRIGUES DOMINGOS J. , IZZO THIAGO J. 
Published: May 2013

Recently, several studies have focused on structural properties of ant–plant networks. However, little is known about the role of abiotic factors on these networks.
As a result of different abiotic factors that can affect the patterns of ant–plant interactions, it was tested whether soil pH and canopy cover contribute to variation in the nestedness of mutualistic (plants with extrafloral nectar–EFN) and neutral (plants without EFN) ant–plant networks.
It was shown that only mutualistic networks were affected by soil pH. It was suggested that this may occur because the variation in soil pH directly influences the secreted nectar, and as there is a preference for nectar composition by ants, this could change the patterns of interaction in mutualistic networks. As prey availability is possibly the main factor influencing ants' presence on plants without EFN, soil pH should have little or no influence on the patterns of interaction in neutral networks.
On the other hand, nestedness was not affected by canopy cover in mutualistic and neutral networks. In spite of that canopy cover (light availability) is directly related to the amount of nectar secreted, the volume of nectar may not be important for the structure of the networks. However, canopy cover varied little in this study site. This small variation could not be enough to change the nested pattern in mutualistic and neutral networks.
In short, the present results show that the abiotic factors that affect the availability and quality of food resources may have important effects on the structure of trophic interactions in non‐symbiotic ant–plant networks.
Size structure, not metabolic scaling rules, determines fisheries reference points
Authors: Andersen Ken H , Beyer Jan E 
Published: May 2013

AbstractImpact assessments of fishing on a stock require parameterization of vital rates: growth, mortality and recruitment. For ‘data‐poor’ stocks, vital rates may be estimated from empirical size‐based relationships or from life‐history invariants. However, a theoretical framework to synthesize these empirical relations is lacking. Here, we combine life‐history invariants, metabolic scaling and size‐spectrum theory to develop a general size‐ and trait‐based theory for demography and recruitment of exploited fish stocks. Important concepts are physiological or metabolic scaled mortalities and flux of individuals or their biomass to size. The theory is based on classic metabolic relations at the individual level and uses asymptotic sizeW∞as a trait. The theory predicts fundamental similarities and differences between small and large species in vital rates and response to fishing. The central result is that larger species have a higher egg production per recruit than small species. This means that density dependence is stronger for large than for small species and has the consequence that fisheries reference points that incorporate recruitment do not obey metabolic scaling rules. This result implies that even though small species have a higher productivity than large species their resilience towards fishing is lower than expected from metabolic scaling rules. Further, we show that the fishing mortality leading to maximum yield per recruit is an ill‐suited reference point. The theory can be used to generalize the impact of fishing across species and for making demographic and evolutionary impact assessments of fishing, particularly in data‐poor situations.
Bypass therapy assay testing as a strategy to reduce costs for treatment of haemophilia patients with inhibitors
Authors: Hay J. W. , Chaugule S. C. , Young G. 
Published: May 2013

SummaryPublished studies suggest that bypass therapy assay testing can be used to predict treatment response and dosing requirements for haemophilia patients with inhibitors. The aim of this study was to evaluate the costs of utilizing and not utilizing bypass therapy assay testing before treating mild‐to‐moderate bleeding episodes on‐demand in haemophilia patients with inhibitors from a US third‐party payer perspective. In our exploratory decision tree model, the average patient was assumed to be an adult weighing 75 kg. Based on existing head‐to‐head clinical trials, the efficacy of activated prothrombin complex (aPCC) and recombinant factor VIIa (rFVIIa) was assumed to be equivalent and based on expert opinion of the haematologist in our study it was conservatively assumed that assay testing improves the efficacy of both the bypassing agents by 10%. Probabilistic and one‐way sensitivity analyses were used to determine the robustness of the results. Cost savings per bleeding episode were estimated at $6886 (95% CI = $4310–7978) for aPCC and $7647 (95% CI = $3134–10 388) for rFVIIa treatment. This translates in potential cost savings of 24.8% (95% CI = 15.5–28.8%) for aPCC use and 18.2% (95% CI = 8–24.7%) for rFVIIa use. Furthermore, if testing successfully predicts the optimum dose for concomitant therapy at the onset of bleeding, significant cost savings were observed compared with rFVIIa and aPCC therapies alone. Use of bypass therapy assay testing before treatment administration in haemophilia inhibitor patients can potentially reduce treatment costs significantly while optimizing dose and therapy response.
Comparison of Interictal Vestibular Function in Vestibular Migraine vs Migraine Without Vertigo
Authors: Boldingh Marion Ingeborg , Ljøstad Unn , Mygland Åse , Monstad Per 
Published: May 2013

BackgroundPatients with vestibular migraine (VM) suffer attacks of vertigo that often occur in isolation from headache attacks. We aimed to assess and compare vestibular function interictally in patients with VM and patients with migraine without vertigo (M).MethodsThirty‐eight patients diagnosed with definite VM according to the Neuhauser criteria, and 32 patients diagnosed with M according to the International Headache Society criteria were examined between attacks using a broad battery of bedside vestibular tests, a caloric test, and videonystagmography.ResultsOverall, 70% of the VM patients and 34% of the M patients showed abnormalities on one or more of the 14 performed vestibular tests (P = .006). Abnormal findings were more frequent in VM than in M patients on Romberg's test, test for voluntary fixation suppression of the vestibular ocular reflex and test for static positional nystagmus (P = .03, .01 and .04, respectively). There were no differences in the distribution of central and peripheral vestibular signs between VM and M patients.ConclusionsVestibular abnormalities were present interictally among both VM and M patients, but were found about twice as frequently among VM patients. This may indicate that subclinical vestibular dysfunction is an integral part of migraine pathology in general, and not solely in VM.
Women, trauma and substance abuse: Understanding the experiences of female survivors of childhood abuse in alcohol and drug treatment
Authors: Salter Michael , Breckenridge Jan 
Published: May 2013

Despite the available evidence suggesting gender should be considered in the provision of alcohol and/or drug (AOD) treatment, programmes are frequently offered in an apparent ‘gender vacuum’. This article argues that the generalist ‘one size fits all’ approach of many AOD services is not gender neutral but should be understood as implicitly gendered in that it neglects the specificity of women's needs in relation to abuse, mental illness and parenting. The discussion presented in this article is based on a qualitative study of the experiences of adult women with histories of childhood sexual abuse and/or domestic violence in AOD treatment. By examining the ways in which AOD treatments effectively ignore or minimise gender, this article uncovers intervention practices that efface the complexities underpinning AOD use among women and suggests ways in which alternative models of service delivery can create more validating and supportive environments.Key Practitioner Message: ● Some of the common assumptions underpinning alcohol and drug treatment do not adequately acknowledge the specific needs of female clients and so gender‐neutral service provision can be disenabling for women; ● Punitive service cultures or behaviour change strategies have a differential impact on female clients, many of whom have prior and ongoing experiences of abuse and violence; ● Service models that acknowledge the complex responsibilities and relational histories of female clients are more likely to engender a positive response and provide the opportunity to address the multiple and complex needs that can go unmet in non‐specialist services.