bluuebunny/crossref_metadata_2025_split huggingface dataset:
Allyloxyporphyrin‐Functionalized Multiwalled Carbon Nanotubes: Synthesis by Radical Polymerization and Enhanced Optical‐Limiting Properties
Authors: Wang Aijian , Fang Yu , Yu Wang , Long Lingliang , Song Yinglin , Zhao Wei , Cifuentes Marie P. , Humphrey Mark G. , Zhang Chi 
Published: November 2013

AbstractAllyloxyporphyrin‐functionalized multiwalled carbon nanotubes (MWCNT‐TPP) were synthesized by radical polymerization and characterized by FTIR, UV/Vis absorption, and X‐ray photoelectron spectroscopy; elemental analysis; TEM; and thermogravimetric analysis. Z‐scan studies revealed that this nanohybrid exhibits enhanced nonlinear optical (NLO) properties compared to a control sample consisting of a covalently unattached physical blend of MWCNTs and porphyrin, as well as to the separate MWCNTs and porphyrin. At the wavelengths used, the mechanism of enhanced optical limiting likely involves reverse saturable absorption, nonlinear scattering, and photoinduced electron/energy transfer between the MWCNTs and the porphyrin. The role of electron/energy transfer in the NLO performance of MWCNT‐TPP was investigated by Raman and fluorescence spectroscopy.
Risk factors and demographics for microtia in South America: A case–control analysis
Authors: Luquetti Daniela V. , Saltzman Babette S. , Lopez‐Camelo Jorge , Graça Dutra Maria da , Castilla Eduardo E. 
Published: November 2013

BACKGROUNDThe etiopathogenesis of microtia is still unknown in the majority of the cases, particularly for individuals presenting with isolated microtia. Our aim was to evaluate potential risk factors for this condition using a case–control approach.METHODSWe analyzed data from 1,194 live births with isolated microtia enrolled in the ECLAMC study (Estudio Colaborativo Latino Americano de Malformaciones Congénitas) from 1982 to 2011 and their respective controls. Odds ratios (ORs) were estimated with logistic regression models along with 95% confidence intervals for the resulting OR estimates controlling for the effects of potential confounders (sex, maternal age, hospital, and year of birth) for an adjusted OR (aOR).RESULTSMultiparity was associated with a higher risk of microtia compared with primiparity (aOR, 1.5; 95% confidence interval [CI], 1.2–1.8), with women who had eight or more prior pregnancies having the highest risk (aOR, 2.8; 95% CI, 1.6–5.2). Women who presented with cold‐like symptoms were at higher risk for microtia (aOR, 2.2; 95% CI, 1.2–3.9) as well as those that used tobacco or alcohol during pregnancy (aOR, 1.7; 95% CI, 1.1–2.6 and aOR, 1.4; 95% CI, 0.9–2.1, respectively). The association with alcohol use appeared to be limited to those women who reported binge drinking during pregnancy (aOR, 1.4; 95% CI, 0.7–3.1). Cases from hospitals at low altitude (<2500 m) tended to have more severe types of microtia than those from hospitals at high altitude.CONCLUSIONThese results support the hypothesis that, in addition to teratogens, other nongenetic risk factors contribute to the occurrence of isolated microtia. Birth Defects Research (Part A) 97:736–743, 2013. © 2013 Wiley Periodicals, Inc.
Noninvasive detection of lung cancer using exhaled breath
Authors: Fu Xiao‐An , Li Mingxiao , Knipp Ralph J. , Nantz Michael H. , Bousamra Michael 
Published: November 2013

AbstractEarly detection of lung cancer is a key factor for increasing the survival rates of lung cancer patients. The analysis of exhaled breath is promising as a noninvasive diagnostic tool for diagnosis of lung cancer. We demonstrate the quantitative analysis of carbonyl volatile organic compounds (VOCs) and identification of lung cancer VOC markers in exhaled breath using unique silicon microreactor technology. The microreactor consists of thousands of micropillars coated with an ammonium aminooxy salt for capture of carbonyl VOCs in exhaled breath by means of oximation reactions. Captured aminooxy‐VOC adducts are analyzed by nanoelectrospray Fourier transform‐ion cyclotron resonance (FT‐ICR) mass spectrometry (MS). The concentrations of 2‐butanone, 2‐hydroxyacetaldehyde, 3‐hydroxy‐2‐butanone, and 4‐hydroxyhexenal (4‐HHE) in the exhaled breath of lung cancer patients (n = 97) were significantly higher than in the exhaled breath of healthy smoker and nonsmoker controls (n = 88) and patients with benign pulmonary nodules (n = 32). The concentration of 2‐butanone in exhaled breath of patients (n = 51) with stages II though IV non–small cell lung cancer (NSCLC) was significantly higher than in exhaled breath of patients with stage I (n = 34). The carbonyl VOC profile in exhaled breath determined using this new silicon microreactor technology provides for the noninvasive detection of lung cancer.
Fast Oxidative Removal of Refractory Aromatic Sulfur Compounds by a Magnetic Ionic Liquid
Authors: Jiang Wei , Zhu Wenshuai , Li Huaming , Xue Jun , Xiong Jun , Chang Yonghui , Liu Hui , Zhao Zhen 
Published: November 2013

AbstractMagnetic ionic liquids (MIL) are extensively used in extraction and catalytic processes. Here, a series of MIL, i.e., 1‐n‐butyric acid‐3‐methylimidazolium chloride/xFeCl3 ([C3H6COOHmim]Cl/xFeCl3; x = 0.5, 1, 1.5, 2), were synthesized and characterized by infrared spectroscopy, visible absorption spectrometry, and electrospray ionization mass spectrometry. The MIL [C3H6COOHmim]Cl/2FeCl3 was found to be highly active for the extraction and catalytic oxidative desulfurization of a model oil under mild conditions. Of note, the removal of benzothiophene, which has been regarded as a refractory aromatic sulfur compound, could be achieved at up to 100 % in 10 min. After reaction, the MIL could be easily separated from the model oil by applying an external magnetic field, due to its paramagnetic properties.
Large Platinum Structures as Promising Catalysts for the Oxygen‐Reduction Reaction
Authors: Fortunato Guilherme V. , Venarusso Luna B. , Maia Gilberto 
Published: November 2013

AbstractHerein, Pt and Pd catalysts (in the absence and presence of Fe, concomitantly or not with rutin or quercetin), PtPd and PtAu alloys, and Pt under Au are generated on a glassy carbon (GC) surface by using direct electrodeposition. The electrochemical profiles of these materials are investigated by using cyclic voltammetry and microgravimetry (electrochemical quartz crystal microbalance). Their electrocatalytic activity toward the oxygen‐reduction reaction (ORR) is studied by using hydrodynamic cyclic voltammetry. Physical characterization of the samples is performed by using SEM and energy‐dispersive X‐ray microanalysis. Electrodeposited catalysts that contain Pt exhibit high electrocatalytic activity toward the ORR and reproducible response, in particular at low Pt concentrations in the electrodeposition solution, thus suggesting the possibility of applying these catalysts to acid fuel cells. Large nanorock structures are formed on the GC electrode that is modified with Pt(0.50)/Pd(0.50)+rutin, whereas the GC electrode that is modified with Pd in the presence or absence of Fe, concomitantly or not with rutin or quercetin, shows poor electrocatalytic activity.
Exploring Electronic and Steric Effects on the Insertion and Polymerization Reactivity of Phosphinesulfonato PdII Catalysts
Authors: Neuwald Boris , Falivene Laura , Caporaso Lucia , Cavallo Luigi , Mecking Stefan 
Published: November 2013

AbstractThirteen different symmetric and asymmetric phosphinesulfonato palladium complexes ([{(X1‐Cl)‐μ‐M}n], M=Na, Li, 1=X(P^O)PdMe) were prepared (see Figure 1). The solid‐state structures of the corresponding pyridine or lutidine complexes were determined for (MeO)21‐py, (iPrO)21‐lut, (MeO,Me2)1‐lut, (MeO)31‐lut, CF31‐lut, and Ph1‐lut. The reactivities of the catalysts X1, obtained after chloride abstraction with AgBF4, toward methyl acrylate (MA) were quantified through determination of the rate constants for the first and the consecutive MA insertion and the analysis of β‐H and other decomposition products through NMR spectroscopy. Differences in the homo‐ and copolymerization of ethylene and MA regarding catalyst activity and stability over time, polymer molecular weight, and polar co‐monomer incorporation were investigated. DFT calculations were performed on the main insertion steps for both monomers to rationalize the effect of the ligand substitution patterns on the polymerization behaviors of the complexes. Full analysis of the data revealed that: 1) electron‐deficient catalysts polymerize with higher activity, but fast deactivation is also observed; 2) the double ortho‐substituted catalysts (MeO)21 and (MeO)31 allow very high degrees of MA incorporation at low MA concentrations in the copolymerization; and 3) steric shielding leads to a pronounced increase in polymer molecular weight in the copolymerization. The catalyst properties induced by a given P‐aryl (alkyl) moiety were combined effectively in catalysts with two different non‐chelating aryl moieties, such as cHexO/(MeO)21, which led to copolymers with significantly increased molecular weights compared to the prototypical MeO1.
Synthesis, Biological Evaluation, WAC and NMR Studies of S‐Galactosides and Non‐Carbohydrate Ligands of Cholera Toxin Based on Polyhydroxyalkylfuroate Moieties
Authors: Ramos‐Soriano Javier , Niss Ulf , Angulo Jesús , Angulo Manuel , Moreno‐Vargas Antonio J. , Carmona Ana T. , Ohlson Sten , Robina Inmaculada 
Published: November 2013

AbstractThe synthesis of several non‐carbohydrate ligands of cholera toxin based on polyhydroxyalkylfuroate moieties is reported. Some of them have been linked to D‐galactose through a stable and well‐tolerated S‐glycosidic bond. They represent a novel type of non‐hydrolyzable bidentate ligand featuring galactose and polyhydroxyalkylfuroic esters as pharmacophoric residues, thus mimicking the GM1 ganglioside. The affinity of the new compounds towards cholera toxin was measured by weak affinity chromatography (WAC). The interaction of the best candidates with this toxin was also studied by saturation transfer difference NMR experiments, which allowed identification of the binding epitopes of the ligands interacting with the protein. Interestingly, the highest affinity was shown by non‐carbohydrate mimics based on a polyhydroxyalkylfuroic ester structure.
ChemInform Abstract: Novel Refractory Phase, Ta7Si2(SixB1‐x)2.
Authors: Romaka V. , Fosodeder V. , Rogl P. F. , Ramos E. C. T. , Nunes C. A. , Coelho G. C. , Giester G. 
Published: November 2013

AbstractTa7Si2(Si0.12B0.88)2 is prepared by repeated arc‐melting of the elements followed by annealing at 2000 °C for 100 h or at 2300 °C for 45 h.
ChemInform Abstract: Clusters [Co(As3S3)2]2‐, [Ni(As3S3)2]2‐, and [{Co(en)}6(μ3‐S)4 (AsS3)4]2‐ with Co—As or Ni—As Bonds: Solvothermal Syntheses and Characterizations of Thioarsenates Containing Transition‐Metal Complexes.
Authors: Tang Chunying , Wang Fang , Jiang Wenqing , Zhang Yong , Jia Dingxian 
Published: November 2013

AbstractIn aqueous solution, Co2+ and Ni2+ ions can be coordinated not only by polyamines but also by As2S3 or AsS3 units as in (III) and (IV).
ChemInform Abstract: Enantioselective Conjugate Addition of 3‐Fluorooxindoles to Vinyl Sulfone: An Organocatalytic Access to Chiral 3‐Fluoro‐3‐substituted Oxindoles.
Authors: Dou Xiaowei , Lu Yixin 
Published: November 2013

AbstractThe first asymmetric conjugate addition of title compounds (I) to vinyl sulfones (II), promoted by a tertiary amine‐thiourea bifunctional catalyst is described.
ChemInform Abstract: β‐Hydroxyamide Derivatives of Salicylic Acid as Organocatalysts for Enantioselective Reductions of Prochiral Ketones.
Authors: Turgut Vilmaz , Azizoglu Murat , Erdogan Asli , Arslan Nevin , Hosgoren Halil 
Published: November 2013

AbstractSeven chiral salicylic acid amide derivatives are prepared and tested as catalysts for the asymmetric borane reduction of prochiral ketones.
ChemInform Abstract: Synthesis of Glucose‐Tagged Triazolium Ionic Liquids and Their Application as Solvent and Ligand for Copper(I) Catalyzed Amination.
Authors: Jha Abadh Kishor , Jain Nidhi 
Published: November 2013

AbstractTriazolium based ionic liquids with carbohydrates at the 1‐ and 4‐position are synthesized and utilized as ligands for the CuI‐catalyzed amination of halobenzenes (I).
ChemInform Abstract: Efficient Synthesis of N‐Methylamides and Amines via 4‐(Alkylamino)benzyl‐N‐methylamine as a New Protecting Group.
Authors: Lee Sang‐Hak , Mu Yu , Kim Gun‐Woo , Kim Jin‐Seok , Park Seok‐Hwi , Jin Tian , Lee Kee‐Young , Ham Won‐Hun 
Published: November 2013

AbstractThe convenient and effective protecting group 4‐(dimethylamino)benzyl reported for the synthesis of the title compounds can be cleaved selectively by using TFA.
ChemInform Abstract: Construction of Quaternary Carbon Centers by Using Substitution of γ,γ‐Disubstituted Secondary Allylic Picolinates with Alkylcopper Reagents.
Authors: Feng Chao , Kaneko Yuki , Kobayshi Yuichi 
Published: November 2013

AbstractA convenient protocol using ZnI2 as promotor is developed for the regio‐ and stereoselective substitution of allylic picolinates with alkyl copper reagents, generated from alkylmagnesium halides and CuBr2·Me2S.
ChemInform Abstract: The Pd(0) Nanoparticles Stabilized by Collagen Fibres as a Recyclable Heterogeneous Catalyst for the Stille Reaction under Aerobic Condition.
Authors: Mohammadi‐Aghdam Babak , Bahari Siavash , Molaei Rahim 
Published: November 2013

AbstractA new protocol for the Stille coupling of aryl iodides with organostannanes under aerobic conditions using a collagen fibre‐supported Pd nanoparticle catalyst is developed.The catalyst can be easily recovered by filtration and reused multiple times without significant loss of activity.
ChemInform Abstract: Highly Efficient Synthesis of Mixed 3,3′‐Bisindoles via Rh(II)‐Catalyzed Three‐Component Reaction of 3‐Diazooxindoles with Indoles and Ethyl Glyoxylate.
Authors: Xing Dong , Jing Changcheng , Li Xinfeng , Qiu Huang , Hu Wenhao 
Published: November 2013

AbstractThe title reaction proceeds with excellent diastereoselectivity.
ChemInform Abstract: An Electron Rich Porous Extended Framework as a Heterogeneous Catalyst for Diels—Alder Reactions.
Authors: Gole Bappaditya , Bar Arun Kumar , Mallick Arijit , Banerjee Rahul , Mukherjee Partha Sarathi 
Published: November 2013

AbstractAn electron rich porous metal‐organic framework based on the rigid tetracarboxylic acid TCA is synthesized, which acts as an efficient catalyst for Diels—Alder reactions through encapsulation of the reactants in confined nano‐channels of the framework.
ChemInform Abstract: Polystyrene‐Supported N‐Heterocyclic Carbene—Silver Complexes as Robust and Efficient Catalyst for the Reaction of Carbon Dioxide and Propargylic Alcohols.
Authors: Tang Xiaodong , Qi Chaorong , He Haitao , Jiang Huanfeng , Ren Yanwei , Yuan Gaoqing 
Published: November 2013

AbstractThe catalyst can be reused at least 15 times without a significant loss of activity.
ChemInform Abstract: 2‐Heteroaryl Benzimidazole Derivatives as Melanin Concentrating Hormone Receptor 1 (MCH‐R1) Antagonists.
Authors: Lim Chae Jo , Kim Jeong Young , Lee Byung Ho , Oh Kwang‐Seok , Yi Kyu Yang 
Published: November 2013

AbstractA novel series of 2‐hetaryl‐substituted benzimidazole derivatives (V) (15 examples) are synthesized and evaluated as MCH‐R1 antagonists.
ChemInform Abstract: Synthesis of Some New Fused and Binary 1,3,4‐Thiadiazoles as Potential Antitumor and Antioxidant Agents.
Authors: Hamama Wafaa S. , Gouda Moustafa A. , Badr Marwa H. , Zoorob Hanafi H. 
Published: November 2013

AbstractAnnulation, alkylation and subsequent cyclization, and multicomponent reactions are conducted with aminothiadiazole (I).
ChemInform Abstract: Synthesis of Novel Coumarin Derivatives and in vitro Biological Evaluation as Potential PTP 1B Inhibitors.
Authors: Sun Cheng , Peng Chune , Wang Jian , Wang Quan , Liu Wei , Zhou Honggang , Yang Cheng 
Published: November 2013

AbstractThe new synthesized compounds are tested for their inhibition activity against the protein tyrosine phosphatase 1B (PTB 1B).
ChemInform Abstract: Multicomponent Assembly of 2‐Amino‐4‐substituted 4H‐Chromenes Using Cyclic Michael Donors.
Authors: Lakshmi Neelakandan Vidhya , Kiruthika Selvarangam E. , Perumal P. T. 
Published: November 2013

AbstractIndium trichloride is an efficient catalyst for the synthesis of chromenes (IV), (VI), and (VIII) by a three‐component reaction of salicylaldehydes, malononitriles and cyclic nucleophiles.
ChemInform Abstract: A Simple Synthesis of E‐9‐Aryl‐5‐arylidene‐1‐oxo‐1,2,3,4,5,6,7,8‐octahydroxanthenes and Their Lower Analogues from E,E,‐α,α′‐Diarylidenecycloalkanones
Authors: Samanta Swati , Gupta Arpita Das , Mondal Rina , Mallik Asok K. 
Published: November 2013

Abstractand cyclohexanediones (II)
ChemInform Abstract: Photoassisted Synthesis of Enantiopure Alkaloid Mimics Possessing Unprecedented Polyheterocyclic Cores.
Authors: Kumar N. N. Bhuvan , Mukhina Olga A. , Kutateladze Andrei G. 
Published: November 2013

AbstractA variety of cyclic N‐sulfonyl amidines is constructed through the photoinduced cyclization of the N‐tethered pyrroles to azaxylenes.
ChemInform Abstract: A Flexible Strategy Towards Thienyl‐, Oxazolyl‐ and Pyridyl‐Fused Fluorenones.
Authors: Souibgui Amel , Gaucher Anne , Marrot Jerome , Aloui Faouzi , Mahuteau‐Betzer Florence , Ben Hassine Bechir , Prim Damien 
Published: November 2013

AbstractCompounds (VII) and (VIII) are prepared by the same sequence consisting of heterocycle formation, Suzuki coupling and ring closure.
ChemInform Abstract: Three‐Component Condensation of 5‐Aminoimidazole Derivatives with Aldehydes and Meldrum′s Acid. Synthesis of 3,4,6,7‐Tetrahydroimidazo[4,5‐b]pyridin‐5‐ones.
Authors: Lichitsky B. V. , Komogortsev A. N. , Dudinov A. A. , Krayushkin M. M. 
Published: November 2013

AbstractA convenient method for the synthesis of previously unknown tetraimidazopyridinone derivatives (VI) (11 examples) using a multicomponent reaction is given.
ChemInform Abstract: S‐Pechmann Dye: A Thiolactone‐Containing Organic Dye with a Pronounced Electron‐Accepting Character and Its Solid‐State Photophysical Properties.
Authors: Fukazawa Aiko , Adachi Makoto , Nakakura Ken , Saito Shohei , Yamaguchi Shigehiro 
Published: November 2013

AbstractA sulfur analogue of a Pechmann dye is synthesized.
ChemInform Abstract: A Review of Anaerobic Membrane Bioreactors for Municipal Wastewater Treatment: Integration Options, Limitations and Expectations
Authors: Ozgun Hale , Dereli Recep Kaan , Ersahin Mustafa Evren , Kinaci Cumali , Spanjers Henri , van Lier Jules B. 
Published: November 2013

AbstractReview: 107 refs.
Managing body image difficulties of adult cancer patients: Lessons from available research
Authors: Fingeret Michelle Cororve , Teo Irene , Epner Daniel E. 
Published: November 2013

BACKGROUNDBody image is a critical psychosocial issue for patients with cancer because they often undergo significant changes to appearance and functioning. The primary purpose of this review article was to identify empirically‐supported approaches to treat body image difficulties of adult cancer patients that can be incorporated into high‐quality comprehensive cancer care.METHODSAn overview was provided of theoretical models of body image relevant to cancer patients, and findings were presented from published literature on body image and cancer from 2003 to 2013. These data were integrated with information from the patient‐doctor communication literature to delineate a practical approach for assessing and treating body image concerns of adult cancer patients.RESULTSBody image difficulties were found across patients with diverse cancer sites, and were most prevalent in the immediate postoperative and treatment period. Age, body mass index, and specific cancer treatments have been identified as potential risk factors for body image disturbance in cancer patients. Current evidence supports the use of time‐limited cognitive‐behavioral therapy interventions for addressing these difficulties. Other intervention strategies also show promise but require further study. Potential indicators of body image difficulties were identified to alert health care professionals when to refer patients for psychosocial care, and a framework was proposed for approaching conversations about body image that can be used by the oncologic treatment team.CONCLUSIONSBody image issues affect a wide array of cancer patients. Providers can use available evidence combined with information from the health care communication literature to develop practical strategies for treating body image concerns of patients with cancer. Cancer 2014;120:633–641. © 2013 American Cancer Society.
Intraobserver and interobserver variability in computed tomography size and attenuation measurements in patients with renal cell carcinoma receiving antiangiogenic therapy: Implications for alternative response criteria
Authors: Krajewski Katherine M. , Nishino Mizuki , Franchetti Yoko , Ramaiya Nikhil H. , Van den Abbeele Annick D. , Choueiri Toni K. 
Published: November 2013

BACKGROUNDAlternative response criteria have been proposed in patients with metastatic renal cell carcinoma (mRCC) who are receiving vascular endothelial growth factor (VEGF)‐targeted therapy, including 10% tumor shrinkage as an indicator of response/outcome. However, to the authors' knowledge, intraobserver and interobserver measurement variability have not been defined in this setting. The objective of the current study was to determine intraobserver and interobserver agreement of computed tomography (CT) size and attenuation measurements to establish reproducible response indicators.METHODSSeventy‐one patients with mRCC with 179 target lesions were enrolled in phase 2 and phase 3 trials of VEGF‐targeted therapies and retrospectively studied with Institutional Review Board approval. Two radiologists independently measured the long axis diameter and mean attenuation of target lesions at baseline and on follow‐up CT. Concordance correlation coefficients and Bland‐Altman plots were used to assess intraobserver and interobserver agreement.RESULTSHigh concordance correlation coefficients (range, 0.8602‐0.9984) were observed in all types of measurements. The 95% limits of agreement for the percentage change of the sum longest diameter was −7.30% to 7.86% for intraobserver variability, indicating that 10% tumor shrinkage represents a true change in tumor size when measured by a single observer. The 95% limits of interobserver variability were −16.3% to 15.4%. On multivariate analysis, the location of the lesion was found to significantly contribute to interobserver variability (P = .048). The 95% limits of intraobserver agreement for the percentage change in CT attenuation were −18.34% to 16.7%.CONCLUSIONSIn patients with mRCC who are treated with VEGF inhibitors, 10% tumor shrinkage is a reproducible radiologic response indicator when baseline and follow‐up studies are measured by a single radiologist. Lesion location contributes significantly to measurement variability and should be considered when selecting target lesions. Cancer 2014;120:711–721. © 2013 American Cancer Society.