bluuebunny/crossref_metadata_2025_split huggingface dataset:
Additional benefit of higher dose green tea in lowering postprandial blood glucose
Authors: Lahirin Rita , Permadhi Inge , Mudjihatini Ninik , Ridwan Rahmawaty , Sugianto Ray 
Published: July 2015

Background: Green tea contains catechins that have inhibitory effects on amylase, sucrase, and sodium-dependent glucose transporter (SGLT) which result in lowering of postprandial blood glucose (PBG). This beneficial effect has been widely demonstrated using the usual dose (UD) of green tea preparation. Our study was aimed to explore futher lowering of PBG using high dose (HD) of green tea in healthy adolescents.
Methods: 24 subjects received 100 mL infusion of either 0.67 or 3.33 grams of green tea with test meal. Fasting, PBG at 30, 60, 120 minutes were measured. Subjects were cross-overed after wash out. PBG and its incremental area under the curve (IAUC) difference between groups were analyzed with paired T-test. Cathecin contents of tea were measured using high-performance liquid chromatography (HPLC).
Results: The PBG of HD group was lower compared to UD (at 60 minutes =113.70 ± 13.20 vs 124.16 ± 8.17 mg/dL, p = 0.005; at 120 minutes = 88.95 ± 6.13 vs 105.25 ± 13.85 mg/dL, p < 0.001). The IAUC of HD was also found to be lower compared to UD (2055.0 vs 3411.9 min.mg/dL, p < 0.001).
Conclusion: Additional benefit of lowering PBG can be achieved by using higher dose of green tea. This study recommends preparing higher dose of green tea drinks for better control of PBG.
Modellbasierte Analyse und Bewegungsplanung für das BionicKangaroo
Authors: Graichen Knut , Hentzelt Sebastian , Hildebrandt Alexander , Kärcher Nadine , Gaißert Nina , Knubben Elias 
Published: July 2015

Zusammenfassung
Der Beitrag beschreibt die Modellbildung, Analyse und Bewegungsplanung für das BionicKangaroo, das im Rahmen des Festo Bionic Learning
Networks entwickelt wurde. Zunächst wird auf die Modellierung eingegangen und die prinzipielle Machbarkeit und Stabilisierbarkeit des
Hüpfzyklus anhand eines modellprädiktiven Regelungsansatzes numerisch untersucht. Der eigentliche Reglerentwurf gliedert sich in die
modellbasierte Regelung der Flug- und Bodenphase. Eine zusätzliche Schaltbedingung verbindet die Flug- und Bodenphase miteinander und
initiiert den nächsten Hüpfzyklus durch das Abdrücken vom Boden.
Representation stability for homotopy groups of configuration spaces
Authors: Kupers Alexander , Miller Jeremy 
Published: July 2015

Abstract
We prove that the dual rational homotopy groups of the configuration spaces of a 1-connected manifold of dimension at least 3 are uniformly representation stable in the sense of [6], and that their derived dual integral homotopy groups are finitely generated as

𝖥𝖨

{{\mathsf{FI}}}

-modules in the sense of [4]. This is a consequence of a more general theorem relating properties of the cohomology groups of a 1-connected co-

𝖥𝖨

{{\mathsf{FI}}}

-space to properties of its dual homotopy groups. We also discuss several other applications, including free Lie and Gerstenhaber algebras.
No universal group in a cardinal
Authors: Shelah Saharon 
Published: July 2015

Abstract
For many classes of models, there are universal members in any cardinal λ which “essentially satisfies GCH, i.e., λ = 2<λ,” in particular for the class of models of a complete first-order T (well, if at least λ > |T|). But if the class is “complicated enough”, e.g., the class of linear orders, we know that if λ is “regular and not so close to satisfying GCH”, then there is no universal member. Here, we find new sufficient conditions (which we call the olive property), not covered by earlier cases (i.e., fail the so-called SOP4). The advantage of those conditions is witnessed by proving that the class of groups satisfies one of those conditions.
Weighted a priori estimates with powers of the distance function for elliptic equations
Authors: Toschi Marisa 
Published: July 2015

Abstract
Let u be a weak solution of the equation (-Δ)
m

u = f with Dirichlet boundary conditions in a smooth bounded domain Ω ⊂ ℝ
n
. In this paper, we obtain some estimates for the Green's function associated to this problem. Moreover, under appropriate conditions on p, we prove some weighted Sobolev a priori estimates for the solution u, where the weight is a power of the distance function. This result extends previous work by R. G. Durán and M. Sanmartino ([Indiana Univ. Math. J. 57 (2008), no. 7, 3463–3478] and [Anal. Theory Appl. 26 (2010), no. 4, 339–349]).
Existence of renormalized solutions for some strongly nonlinear elliptic equations in Orlicz spaces
Authors: Fqayeh Azeddine Aissaoui , Benkirane Abdelmoujib , El Moumni Mostafa , Youssfi Ahmed 
Published: July 2015

Abstract
We prove the existence of a renormalized solution for the Dirichlet problem associated to the nonlinear elliptic equations
div a(x,u,∇u) - div Φ(u) + g(x,u,∇u) = f in Ω,
in the general setting of Orlicz spaces, where
Φ ∈ 𝒞0(ℝ,ℝ
N
), the function g has a natural growth with respect to its third argument and satisfies the sign condition while the datum f belongs to
W
-1
E

M¯(Ω). No Δ2-condition is needed for the considered N-functions.
Scale-up of an RF heated micro trickle bed reactor to a kg/day production scale
Authors: Fernández Javier , Chatterjee Sourav , Degirmenci Volkan , Rebrov Evgeny V. 
Published: July 2015

AbstractThe scale-up of a radiofrequency (RF) heated micro trickle bed reactor for hydrogenation of 2-methyl-3-butyne-2-ol (MBY) over a Pd/TiO
The importin α/β-specific inhibitor Ivermectin affects HIF-dependent hypoxia response pathways
Authors: Kosyna Friederike K. , Nagel Marie , Kluxen Larissa , Kraushaar Kim , Depping Reinhard 
Published: July 2015

AbstractHypoxia-inducible transcription factors (HIFs) regulate hundreds of genes involved in cellular adaptation to reduced oxygen availability. HIFs consist of an O2-labile α-subunit (primarily HIF-1α and HIF-2α) and a constitutive HIF-1β subunit. In normoxia the HIF-α subunit is hydroxylated by members of a family of prolyl-4-hydroxylase domain (PHD) proteins, PHD1-3, resulting in recognition by von Hippel-Lindau protein, ubiquitination and proteasomal degradation. In contrast, reduced oxygen availability inhibits PHD activity resulting in HIF-1α stabilisation and nuclear accumulation. Nuclear import of HIF-1α mainly depends on classical nuclear localisation signals (NLS) and involves importin α/β heterodimers. Recently, a specific inhibitor of nuclear import has been identified that inhibits importin α/β-dependent import with no effects on a range of other nuclear transport pathways involving members of the importin protein family. In this study we evaluated the physiological activity of this importin α/β-inhibitor (Ivermectin) in the hypoxia response pathway. Treatment with Ivermectin decreases binding activity of HIF-1α to the importin α/β-heterodimer. Moreover, HIF-1α nuclear localisation, nuclear HIF-1α protein levels, HIF-target gene expression, as well as HIF-transcriptional activity are reduced upon Ivermectin treatment. For the first time, we demonstrate the effect of specific importin α/β-inhibition on the hypoxic response on the molecular level.
What can lipidomics tell us about the pathogenesis of Alzheimer disease?
Authors: Xiang Yanhui , Lam Sin Man , Shui Guanghou 
Published: July 2015

AbstractLipids serve many distinct functions in cellular homeostasis such as membrane organization, as a platform for membrane function and protein/protein or protein/lipid interaction, energy storage, as well as secondary messengers in signal transduction. Perturbations in lipid homeostasis may result in abnormal cellular function. Alzheimer’s disease (AD) is a neurodegenerative disorder in which the brain represents the primary site of pathology. While there is a plethora of previous work pertaining to AD pathogenesis, the precise mechanism of the disease is still not well-understood. Recent waves of technological advances in the realm of lipidomics have enabled scientists to look at AD pathogenesis from a previously unexplored perspective, and studies have revealed extensive lipid aberrations are implicated in the disease pathology. Herein, we review the critical lipids alternations, which affect amyloid plaque and neurofibrillary tangles formation and accumulation, as well as lipid aberrations related to neuronal and synaptic dysfunction in cells and animal models. We also summarize lipid abnormalities observed in the human cerebrospinal fluid (CSF), as well as other circulating fluids including plasma and serum in association with AD, which could serve as candidate biomarkers to diagnose and monitor the disease.
Quantifying and protecting location privacy
Authors: Shokri Reza 
Published: July 2015

Abstract
This thesis addresses the timely concern of protecting privacy in the
age of big data. We identify the two following problems as the
fundamental problems in computational privacy: (i) consistently
quantifying privacy in different systems and (ii) optimally protecting
privacy using obfuscation mechanisms. We cast the problem of
quantifying privacy as computing the estimation error in a statistical
(Bayesian) inference problem, where an adversary combines his
observation, background knowledge and side channel information to
estimate the user's sensitive information. This enables us to evaluate
privacy of users in different systems, and consistently compare the
effectiveness of different privacy protection mechanisms. We also
formulate the problem of optimizing user privacy while respecting data
utility as an interactive optimization problem (Bayesian Stackelberg
game), where both user and adversary want to maximize their own
objectives which are in conflict with each other. We apply our
methodologies to quantifying and protecting location privacy in
location-based services. We also provide an open-source tool, named
Location-Privacy and Mobility Meter (LPM), that enables researchers to
learn and analyze human mobility models as well as evaluating and
comparing different location-privacy preserving mechanisms.
Multidirectional, Multicomponent Electric Field Driven Assembly of Complex Colloidal Chains
Authors: Bharti Bhuvnesh , Velev Orlin D. 
Published: July 2015

Abstract
External fields (magnetic and electric) present a simple, robust and
efficient route to manipulate and assemble colloidal particles. We
report how biparticle dispersions can be assembled into well-defined
arrays of tunable morphology using external AC electric field. Binary
dispersions of strongly and weakly charged colloidal particles were
arranged into linear composite chains via dipole-dipole
attraction. The frequency of the applied electric field was the first
control parameter for reversibly tuning the biparticle attraction from
longitudinal assembly (in the direction of field) to the traverse one
(perpendicular to the field). We show that in addition to frequency,
spatial limitations play a key role in the assembly process and may
assist in the formation of short bidirectional chain-like clusters or
characteristic highly structured strings of colloidal triplets. Thus,
we control the long-range organization through a combination of
particle size ratio, concentration ratio and field frequency. The new
strategy to reconfigure the microstructures can find application in
better control of the field driven colloidal assembly processes and
may be extended to the formation of more complex and precisely
arranged particle networks.
The Battered Child Syndrome
Authors: Brown RH 
Published: July 2015

Abstract
Strange as it may seem, in this era of escalating intellectual enlightement, laws must be passed to protect innocent, harmless children from their parents and others who beat them into senselessness and even death. On 1 July 1965 such a law went into effect in Illinois, and Illinois became the 11th state to enact a child abuse statute [1]. Our law requires mandatory reporting of all definite or suspicious instances of child abuse to the Illinois Department of Children and Family Services. This legislation was drafted and its passage urged by a special committee appointed by the Illinois Commission on Children, of which I was a member. It was also endorsed by the Coroner of Cook County, whose office had examined many of the victims, and by many other interested persons who in their professional activities encountered battered children. All felt that the actual reporting and the concomitant publicity and education would serve as deterrents to this deplorable condition. Today, ten years later, the battered child has not been legislated out of existence, although all states now have similar reporting laws [2]. Both the incidence and the severity of these heinous acts continue to be alarming in our country as well as in many foreign countries [3–9]. Daily a large segment of our citizenry, the battered child, is being deprived of its right to life, liberty, and the pursuit of happiness. Physicians, attorneys, and other professionals must be in the forefront to diagnose the condition, treat the victims, take remedial action against the offenders, and attempt to formulate preventive measures.
Determination of Methaqualone in Urine by Metabolite Detection Via Gas Chromatography
Authors: Permisohn RC , Hilpert LR , Kazyak L 
Published: July 2015

Abstract
Pharmaceutical preparations of the sedative and hypnotic agent methaqualone have been widely prescribed and dispensed under a variety of trade names, including Quaalude®, Sopor®, and Parest®. Cases of methaqualone abuse and overdose have been well documented [1–3]. The ready availability and frequent abuse of methaqualone have led to the development of methods of analysis for methaqualone and its metabolites in biologic fluids. Nowak et al used thin-layer chromatography (TLC) to study the metabolism of methaqualone in laboratory animals [4]. Only a small fraction of the dose was detected as the unchanged drug in the urine of the rat, while the major portion of the dose was hydroxylated and excreted as glucuronide conjugates. Preuss et al isolated twelve metabolites from urine of human subjects who had ingested methaqualone [5]. By comparison of these twelve metabolites with a series of synthesized monohydroxy derivatives of methaqualone they were able to identify five monohydroxy metabolites of the drug.
Combined Effect of Methaqualone and Two Cannabinoids
Authors: Stone CJ , McCoy DJ , Forney RB 
Published: July 2015

Abstract
The purpose of this study was to determine the effect of pretreatment with cannabidiol (CBD) or Δ-9-tetrahydrocannabinol (THC) on methaqualone (MQ)-induced sleeping times. The duration of sleep was determined as the interval between the loss of righting reflex and its return. Male albino mice were injected intraperitoneally (i.p.) with either CBD or THC (10, 20, or 30 mg/kg) or vehicle. Thirty minutes later, an hypnotic dose of MQ (75 mg/kg) was administered. Animals receiving CBD or THC alone would not sleep. The sleeping time for MQ alone was approximately 30 minutes. In the presence of CBD or THC, MQ sleeping times increased significantly. The effect of THC was significantly greater than that of CBD.
The Spatial Distribution of Copper in Individual Human Hairs
Authors: Maes D , Pate BD 
Published: July 2015

Abstract
Studies of the trace element content of human hair are of interest from several points of view. Since trace elements enter hair from the environment; either directly or via the diet, their concentration in hair may represent an indicator of environmental quality [1–3]. Further, since hair samples are fairly durable, those secured in an historical or archeological context may provide environmental information from times past [4]. Erratum to this paper appears in 21(2).
Correlation of Lead and Cadmium in Human Urine
Authors: Lewis SC , Forney RB 
Published: July 2015

Abstract
Beginning in May 1973 the analysis of urine for the presence of cadmium has been performed in this laboratory on a routine basis. During the following months, the subjective impression emerged that when elevated urinary concentrations of lead were found, urinary cadmium concentrations were often elevated also. The present study was undertaken to evaluate the possible statistical relationship between the elevated concentrations of these two elements.
Some Aspects of Normal Behavior: Their Use in Understanding Problems Encountered by Document Examiners
Authors: McCarthy JF 
Published: July 2015

Abstract
It is unfortunate that in this country the need to separate the opinions of document examiners from those of graphologists has directed almost all handwriting research away from the areas of the behavioral sciences and toward the physical sciences. Because of this trend in research, little direct mention is normally made of the relationship of the behavioral sciences to document examination, although it is covertly mentioned in many papers. This attempt to pursue studies only in the pure sciences has placed a self-imposed limit of knowledge on document examination.
A Review of “Forensic Medicine”
Authors: Froede RC 
Published: July 2015

Abstract
The text of this concise volume attempts to cover all major aspects of forensic pathology and forensic medicine. The book is interesting, fairly timely, and easy to read. It is apparently designed to begin the education of the medical student, attorney, and novice criminal investigator in the rudiments of forensic medicine. In this, the book is quite successful, utilizing, in part, a format of question and answer. This can be particularly useful to a person who is developing a technique or method of investigation for the casual medicolegal case. This is the second edition of this little book that has found its way into my library, and I use it to give to a student to read over several days as a start in the field.
A Review of “Bedeutung und gerichtsmedizinische Anwendung der DNS-Fluorochromierung von Chromosomen und Zellkernen”
Authors: Bahr GF 
Published: July 2015

Abstract
In this book the author explores the use of the quinacrine fluorochrome in forensic medicine. Caspersson has already indicated that homologue differences might be a personal identifying feature. The author discusses this aspect of cytogenetics and points to the difficulties, mostly of a technical nature.
The Forensic Taxonomic Debate on Cannabis: Semantic Hokum
Authors: Small E 
Published: July 2015

Abstract
Since 1972 there have been numerous cases in North America in which the applicability of legislation governing marihuana has been challenged on the basis of a superficially meritorious argument. In brief, the defense has been advanced that there are several species of the marihuana plant, and since most legislation refers only to the species Cannabis sativa, the other species and marihuana obtained from such other species are not proscribed. This defense has been used so extensively that it has become a textbook exemplar [1]. Recent articles supporting its validity [2–4] have exacerbated the situation.
Extraction Procedures for Some Common Drugs in Clinical and Forensic Toxicology
Authors: Hackett LP , Dusci LJ , McDonald IA 
Published: July 2015

Abstract
There are many reports in the literature which deal with general screening methods for drugs in both clinical patients and postmortem specimens [1–13]. Much attention has been given to the clinical aspects where urgent identification and quantitation of unknown drugs are required. Of prime importance in this work is the selection of a suitable extraction technique. The number of available drugs has increased enormously since the more popular extraction methods were described, when at that time most overdoses involved acidic drugs (salicylates and barbiturates). These extraction systems have not been adequately evaluated with many of the more modern and predominantly basic drugs.
Concentrations of Ethanol in Two Segments of the Vascular System
Authors: Sedman AJ , Wilkinson PK , Wagner JG 
Published: July 2015

Abstract
The determination of ethanol is probably one of the most frequently requested tests in the forensic or clinical toxicology laboratory [1]. Large differences in ethanol distribution between whole blood and various human tissue have been reported [2] as well as ethanol concentration gradients within human and animal vascular systems [3–8]. Forney [9] reported that during the absorption-distribution phase, after the oral administration of ethanol, the “concentration of alcohol in arterial blood may be 50 to 100 percent higher than it (is) in venous blood.” During this time blood from an arm vein will not truly reflect the concentration of ethanol supplied to the brain, where its effects are produced. These vascular ethanol concentration gradients generally have been ignored, possibly because the reports of other authors [3–6] have indicated that the arteriovenous (A/V) equilibrium of ethanol is attained rapidly in man when ethanol is administered by rapid intravenous infusion. Dundee et al [4] stated that after oral administration the A/V ratio reaches unity much more slowly than when alcohol is given intravenously. Harger [10] pointed to errors from using venous blood during the absorption phase after oral administration of ethanol. This work substantiates and extends the capillary-venous ethanol concentration differences reported in the literature and illustrates that equal capillary and venous ethanol concentration may not be achieved readily after the oral administration of ethanol to man.
Sex-Chromatin Bodies in Penile Washings as an Indicator of Recent Coitus
Authors: Given BW 
Published: July 2015

Abstract
Within the past decade several sociologic factors have contributed to a relaxation and greater candor in all spheres of sexual concern, including an increased awareness of the crime of rape. As this crime has burgeoned, so too has the literature of the forensic sciences regarding techniques for the analysis and evaluation of medicolegal evidence of alleged rape.
A Potential Young Murderer
Authors: Evseeff GS 
Published: July 2015

Abstract
The genesis of crime is as complex as human nature itself. It has its past and present history. This author had an opportunity to study, examine, and treat a number of people who were involved in a series of crimes beginning in childhood and, with some of them, continuing into adulthood and eventuating in homicides. One common denominator in the lives of these people was exposure to hostility, brutality, and seductiveness in their early years of life. Today we hear so much more about the child-abuse phenomenon as psychopathology of the parents than we do about the impact such violent behavior has on the subsequent development of the child. Preemptive approach to this problem is that such direct experiences of violence have a disorganizing effect on future growth and development of the psychic apparatus of a child.
Death from Intravenously Administered Narcotics: A Study of 114 Cases
Authors: Richards RG , Reed D , Cravey RH 
Published: July 2015

Abstract
The attempt to explain the pathophysiology of deaths from intravenously administered narcotics has been hindered in the past because of the small number of fatal cases reported annually in most areas of the United States and relatively insensitive toxicological methods. A sudden and dramatic increase in deaths attributed to intravenously administered narcotics together with improved and sensitive methods for the identification and quantitation of the major metabolite of heroin in tissues have provided the forensic pathologist with the necessary tools to re-evaluate this type of fatality.