bluuebunny/crossref_metadata_2025_split huggingface dataset:
CoCoNest: A continuous structural connectivity-based nested family of parcellations of the human cerebral cortex
Authors: Allen Adrian , Zhang Zhengwu , Nobel Andrew 
Published: August 2024

Abstract
Despite the widespread exploration and availability of parcellations for the functional connectome, parcellations designed for the structural connectome are comparatively limited. Current research suggests that there may be no single “correct” parcellation and that the human brain is intrinsically a multiresolution entity. In this work, we propose the Continuous Structural Connectivitity-based, Nested (CoCoNest) family of parcellations—a fully data-driven, multiresolution family of parcellations derived from structural connectome data. The CoCoNest family is created using agglomerative (bottom-up) clustering and error-complexity pruning, which strikes a balance between the complexity of each parcellation and how well it preserves patterns in vertex-level, high-resolution connectivity data. We draw on a comprehensive battery of internal and external evaluation metrics to show that the CoCoNest family is competitive with or outperforms widely used parcellations in the literature. Additionally, we show how the CoCoNest family can serve as an exploratory tool for researchers to investigate the multiresolution organization of the structural connectome.
Challenges in building scholarly knowledge graphs for research assessment in open science
Authors: Manghi Paolo 
Published: August 2024

Abstract
Open science has revolutionized scholarly communication and research assessment by introducing research data and software as first-class citizens. Scholarly knowledge graphs (SKGs) are expected to play a crucial role in generating research assessment indicators being able to aggregate bibliographic metadata records and semantic relationships describing all research products and their links (e.g., citations, affiliations, funding). However, the rapid advance of open science has led to publication workflows that do not adequately support and guarantee the authenticity of products and metadata quality required for research assessment. Additionally, the heterogeneity of research communities and the multitude of data sources and exchange formats complicate the provision of consistent and stable SKGs. This work builds upon the experience gained from pioneering and addressing these challenges in the OpenAIRE Graph SKG. The aim is twofold and broader. First, we identify obstacles to the creation of SKGs for research assessment caused by the state-of-the-art publishing workflows for publications, software, and data. Second, we describe repurposing SKGs as tools to monitor such workflows to identify and heal their shortcomings, taking advantage of tools, techniques, and practices that support the actors involved, namely research communities, scientists, organizations, data source providers, and SKG providers, to improve the Open Science scholarly publishing ecosystem.
The formulation of three Pochonia chlamydosporia isolates and their effectiveness as biocontrol agents of Meloidogyne javanica
Authors: Imani Saeid , Moosavi Mohammad Reza , Zare Rasoul , Basirnia Tahere 
Published: August 2024

Summary
The chlamydospore production of three Pochonia chlamydosporia isolates from two different varieties was evaluated on flaxseed and rice husk, testing their survival on talc, kaolin and maize cob powder. The effect of each formulation in suppressing Meloidogyne javanica on tomato was also investigated in glasshouse trials. For all isolates, the number of chlamydospores produced on flaxseed was about twice that observed on rice husk (i.e., 8 weeks after inoculation, isolate IRAN 1119 C produced 98 × 106 and 50 × 106 chlamydospores on flaxseed and rice husk, respectively). Isolate IRAN 1212 C produced more chlamydospores with longer lifespan compared with the other fungi. IRAN 1212 C on maize cob powder could reduce M. javanica by 95% at a level similar to fluopyram. This prototype formulation had a superior effect in establishing the fungus in the rhizosphere and on roots, suppressing the nematode and increasing plant growth. The three P. chlamydosporia isolates reproduced well on flaxseed and could last longer if formulated on maize cob powder, which appears suitable to produce an effective powdered formulation.
A Note on Klb yārh in al-Bīrūnī’s Autobibliography
Authors: Kahl Oliver 
Published: August 2024

Abstract
This short article proposes two possible explanations of the opaque term klb yārh (كلب ياره), which makes an isolated appearance in the autobibliography of Abū Rayḥān al-Bīrūnī (d. ca. 440/1048). There, it is registered as the title of an otherwise unknown Indian medical work which al-Bīrūnī himself says he translated from Sanskrit into Arabic.
Development of Polar Lows in Future Climate Scenarios over the Barents Sea
Authors: Lin Ting , Rutgersson Anna , Wu Lichuan 
Published: August 2024

Abstract
Polar lows (PLs) are intense mesoscale cyclones that form over polar oceans during colder months. Characterized by high wind speeds and heavy precipitation, they profoundly impact coastal communities, shipping, and offshore activities. Amid the substantial environmental changes in polar regions due to global warming, PLs are expected to undergo noteworthy transformations. In this study, we investigate the response of PL development in the Barents Sea to climate warming based on two representative PLs. Sensitivity experiments were conducted including the PLs in the present climate and the PLs in a pseudo–global warming scenario projected by the late twenty-first century for Shared Socioeconomic Pathway (SSP) 2-4.5 and SSP 3-7.0 scenarios from phase 6 of the Coupled Model Intercomparison Project (CMIP6). In both warming climate scenarios, there is an anticipated decrease in PL intensity, in terms of the maximum surface wind speed and minimum sea level pressure. Despite the foreseen increase in latent heat release in the future climate, contributing to the enhancement of PL intensity, other primary factors such as decreased baroclinic instability, heightened atmospheric static stability, and reduced overall surface heat fluxes play pivotal roles in the overall decrease in PL intensity in the Barents Sea under warming conditions. The augmentation of surface latent heat flux, however, results in increased precipitation associated with PLs by enhancing the latent heat release. Furthermore, the regional steering flow shifts in the warming climate can influence the trajectory of PLs during their development.

Significance Statement
Global warming is anticipated to impact cyclone systems worldwide. Polar lows (PLs), intense mesocyclones in polar regions with potential socioeconomic and human life implications, pose uncertainties regarding intensity changes in a warming climate. In this study, we aimed to better understand how PLs over the Barents Sea will respond to the environmental changes in future climate conditions [Shared Socioeconomic Pathway (SSP) 2-4.5 and SSP 3-7.0] by the end of the twenty-first century. Our results find that the intensity of PLs is expected to decrease in the future while there is an expected increase in precipitation associated with PLs in the warming climate. These findings aim to contribute valuable insights for disaster management strategies in the face of evolving climate scenarios.
Une collaboration entre sociologues et mathématiciennes : entretiens (auto)biographiques, ethos mathématicien et carrières féminines au Chili
Authors: Hersant Jeanne , Gajardo Andrea Vera , Trumper Mariel Saez 
Published: August 2024

Résumé Cet article rend compte d’un processus de recherche sur le champ des mathématiques au Chili, et en particulier sur la carrière des femmes dans le milieu scientifique, et l’ethos mathématicien. Ce projet a été mené à bien par une équipe de chercheur·e·s composée à parité de sociologues et mathématiciennes, ce qui constitue selon nous une expérience innovante d’interdisciplinarité. Nous l’abordons ici de façon réflexive, en la situant par rapport à la littérature sur l’interdisciplinarité et l’épistémologie féministe. Ensuite, nous présentons la méthodologie que nous avons mise en œuvre, celle des entretiens biographiques articulée à l’auto-ethnographie des mathématiciennes de l’équipe. Nous souhaitons enfin mettre en lumière les hiatus que cette collaboration interdisciplinaire a permis d’identifier, et les enseignements que nous en avons tiré quant à la constitution de l’ethos mathématicien.
A novel approach to remove retained lens material: Suction-assisted elevation and anterior chamber phacoemulsification
Authors: De Vitto Antonia Maria Luce , Santorum Paolo , Bertelli Enrico 
Published: August 2024

Purpose To describe and evaluate the feasibility of a novel pars plana vitrectomy (PPV) technique for the removal of retained lens material (RLM), which obviates the need for either 20-gauge intravitreal fragmentation or perfluorocarbon-assisted elevation. Methods Interventional case series. After thorough 23-gauge PPV, the hard lens material is engaged and held adherent to the vitreous cutter using aspiration, then raised into the anterior chamber. There, a standard phacoemulsification probe, inserted through a corneal incision, is used to fragment and remove the material. Results Three eyes of 3 patients were operated on. In all eyes, RLM could be removed completely. Postoperatively, 2 of 3 eyes (67%) achieved 20/20 best-corrected visual acuity. No complications such as glaucoma, cystoid macular edema, corneal edema, or retinal detachments were recorded. Intraoperatively, retinal tears were detected in 2 of 3 (67%) eyes and treated with endolaser retinopexy and fluid-air exchange. One eye subsequently developed macular hole requiring further surgery. Conclusion Suction-assisted lens elevation may be a viable and convenient technique to remove RLM during PPV. Although the comparison with other methods is beyond the scope of this preliminary study, visual outcomes and complication rates were encouraging and should be validated in a larger group of patients.
Multiple medications and quality of life of Nigerians with primary open angle glaucoma
Authors: Nnubia Chinasa Anderline , Nwosu Sebastian Ndulue Ntuko , Okpala Nonso Ejikeme , Apakama Akunne Ijeoma , Orji Ifeanyi James , Uba-Obiano Chizoba Udoka , Onyiaorah Adaora Amaoge 
Published: August 2024

Purpose To determine the impact of multiple medications on the quality of life of primary open angle glaucoma (POAG) patients on medical treatment at Guinness Eye Centre Onitsha, Nigeria Materials and Methods Adult patients diagnosed with POAG who were undergoing medical therapy were selected through systematic sampling. They were asked to provide information on socio-demographic background, the number and types of glaucoma medications they were using and any adverse effects encountered while using these medications. The patients’ quality of life was assessed by utilizing the National Eye Institute Visual Function Questionnaire-25 (NEI-VFQ-25) and all patients completed ocular examination. Data analysis was with Statistical Package for Social Sciences (SPSS) version 23. Results One hundred and seventy-one patients, aged 40–83 years, mean 59.1 ± 11.1 were studied; there were 79(46.2%) males and 92(53.8%) females. One hundred and nine (63.7%) patients were on multiple medications. Side effects of treatment increased with increasing number of medications. The mean quality of life score in monotherapy group and double therapy group were 89.3 ± 15.8 and 80.2 ± 21.1 respectively; while that in ≥ triple therapy group was 78.9 ± 18.8. This decrease in mean quality of life score with increasing number of medications was statistically significant in bivariate analysis ( P < 0.01), however, multiple regression analysis showed that the number of medications did not significantly affect the quality of life scores after adjusting for confounding variables( p = 0.881). Conclusion Among the patients studied, use of multiple medications, unlike visual acuity (VA) and severity of glaucoma, was not an independent predictor of quality of life.
Effectiveness and safety of istent inject as an interventional glaucoma approach for uncontrolled open-angle glaucoma
Authors: Vizzari Gabriele , Ceruti Piero 
Published: August 2024

Introduction To describe the results of iStent inject implantation as a standalone procedure in early-stage uncontrolled glaucoma, with results up to 24 months. Methods A retrospective, single-center case series that recruited patients with open-angle glaucoma (OAG), uncontrolled IOP (defined as ≥18 mmHg), and who are receiving 1–4 glaucoma medications were implanted the iStent inject as a standalone procedure. Exclusion criteria were the contraindications of iStent inject implantation. Primary outcome measures were IOP at 6, 12, 18, and 24 months compared to baseline, and the number of medications at baseline and 24 months. Results Eighty-eight eyes from 88 patients, aged 57.6 ± 9.8 years, were included. Ten eyes underwent a subsequent glaucoma procedure during follow-up and were excluded from the analysis. The mean IOP (mmHg) was reduced from 20.54 ± 1.42 at baseline to 15.99 ± 1.98 and 16.15 ± 2.21 (n = 78, p < 0.001) at the 12- and 24-month follow-up, respectively, and the mean number of medications was reduced from 2.35 ± 0.70 to 1.31 ± 0.80 (p < 0.001) at 24 months. Of those eyes, 59% had ≥20% reduction in IOP at 24 months, 91% had an IOP ≤18 mmHg at 24 months, and 71.8% were receiving fewer medications. At 24 months, 14.1% of eyes were medication-free, compared to none at baseline. No serious intraoperative or postoperative adverse events occurred. Discussion iStent inject can effectively control intraocular pressure in mild glaucoma, reducing medication reliance and improving patient quality of life.
Posterior staphyloma-induced serous maculopathy: Evolution and successful treatment with subthreshold micro pulse Laser
Authors: Kathare Rupal , Gandhi Priyanka , Prabhu Vishma , Bavaskar Snehal , Chhablani Jay , Venkatesh Ramesh 
Published: August 2024

Purpose To describe the evolution of posterior staphyloma-induced serous maculopathy (PSISM) in a patient with myopic tilted disc syndrome and its treatment with subthreshold micro pulse laser (SMPL) therapy. Case description A 38-year-old male, diagnosed previously with classical features of myopic tilted disc syndrome presented to the retina clinic after 5 years from the initial presentation with blurred vision in the right eye for 6 months, visual acuity of 6/15 and findings of serous macular detachment (SMD) and subretinal precipitates at the upper margin of the posterior staphyloma. Retinal imaging ruled out other causes of SMD such as chronic central serous chorioretinopathy, myopic macular neovascularisation and dome shaped macula. A diagnosis of PSISM was confirmed. The left eye fundus and macula was normal. Results Confluent SMPL burns were applied across the SMD. The serous maculopathy resolved over a period of 2 months and visual acuity improved to 6/9. No recurrence of SMD was noted even after 14 months post SMPL. Conclusion PSISM develops gradually in eyes with myopic titled disc syndrome. SMPL is a viable therapeutic option in the management of PSISM and should be considered early in the treatment options.
Significantly increasing multiple sclerosis prevalence in Australia from 2010 to 2021
Authors: Campbell Julie A , Simpson-Yap Steve , Taylor Bruce V , van der Mei Ingrid , Laslett Laura , Henson Glen , Zhao Ting , Palmer Andrew J 
Published: August 2024

Background: Multiple sclerosis (MS) prevalence is increasing globally. Objectives: To determine whether increased prevalence is continuing within Australia using our validated prescription-based ascertainment method. Methods: We used methods employed in our 2010 and 2017 prevalence estimates. Disease-modifying therapy (DMT) prescriptions were extracted from Australia’s Pharmaceutical Benefits Scheme data for January–December 2021. DMT penetrance was calculated using data from the Australian MS Longitudinal Study. We divided the total number of monthly prescriptions by 12 or 2 (except alemtuzumab), adjusted for DMT penetrance and Australian population estimates. Prevalences in Australian states/territories were age-standardised. 2021 prevalence estimates were compared with 2010 and 2017 prevalence estimates using Poisson regression. Results: Number of people with MS in Australia in 2021 was 33,335; an increase of 7728 from 2017 (30.2%) and 12,092 from 2010 (56.6%) and increasing at a faster rate than population change (+10.1%, +14.1%). Age-standardised prevalence was 136.1/100,000 (increased from 103.7/100,000 in 2017). The previously demonstrated positive latitudinal gradient in 2010 and 2017 persisted in 2021, with Tasmania (southernmost state) having the highest prevalence (age-standardised: 203.5/100,000) while northernmost states had the lowest. Conclusions: In line with global trends, MS prevalence is escalating in Australia, particularly in higher-latitude states. MS prevention is crucial to halt this disturbing trend.
Association between childhood family structure and health-related quality of life at middle age: A longitudinal study of Northern Finland Birth Cohort 1966
Authors: Varis Heidi , Heikkala Eveliina , Mikkola Ilona , Nordström Tanja , Taanila Anja , Keinänen-kiukaanniemi Sirkka , Hagnäs Maria 
Published: August 2024

Aims: This longitudinal study evaluated the association between childhood family structure and health-related quality of life (HRQoL) at middle age. Methods: The data on childhood family structure at the age of 14 years (‘two-parent family’, ‘one parent not living at home/no information on father’ and ‘father or mother deceased’) and HRQoL (measured by 15D (15-dimensional)) at the age of 46 were collected from the Northern Finland Birth Cohort 1966 using postal questionnaires. We used the binary logistic regression model to estimate the associations between childhood family structures and the lowest 15D quartile (reference: all other quartiles). The associations were adjusted for offspring mothers’ factors during pregnancy (mothers’ educational and occupational status). Results: Of the 6375 participants, the offspring belonging to the ‘one parent not living at home/no information on father’ family structure subgroup had higher odds ratio of belonging to the lowest 15D quartile than the offspring of ‘two-parent families’ (adjusted odds ratio (OR) 1.76, 95% confidence interval (CI) 1.31–2.36, p<0.001 for females; adjusted OR 1.86, 95% CI 1.28–2.70, p=0.001 for males). There were no statistically significant associations between the ‘father or mother deceased’ subgroup and the lowest 15D quartile among the offspring. Conclusions: A single-parent family origin (due to reasons other than parental death) in childhood was significantly associated with impaired HRQoL at middle age. These results provide new perspectives for understanding the long-standing associations on living in a single-parent family.
Below-the-Ankle Antegrade Teleferic Technique: New Approach for Below-the-Ankle Revascularization in Challenging Cases of Chronic Limb-Threatening Ischemia
Authors: Lobato Marta , Ysa August , Arruabarrena Amaia , Martínez Esther , Fonseca Juan L. , Patrone Lorenzo 
Published: August 2024

Purpose: To describe a novel bailout technique to approach below-the-ankle (BTA) chronic total occlusions or plantar-arch severe disease where the balloon/catheter is unable to follow the crossing guidewire and no other described recanalization approach is feasible. Technique: When facing a complex BTA revascularization, if the guidewire crosses but the balloon cannot progress due to a lack of pushability, an antegrade puncture of the infrapopliteal vessel where the tip of the guidewire lays is performed. The guidewire is then carefully navigated through this distal BTA vessel into the needle to achieve its rendezvous and externalization. A low-profile balloon is inserted through the femoral access and advanced till the non-crossable point of the BTA vessels. A torque device is then attached to the proximal hub of the balloon, and the through-and-through guidewire is subsequently pulled from the new distal access, allowing the balloon to be dragged across the lesion together with the wire. Conclusion: The below-the-ankle antegrade teleferic (BAT) technique may be considered for highly complex BTA revascularization procedures where the wire crosses the lesion, but no other device can be tracked over it. Clinical Impact The clinical impact of this article lies in the description of a bailout technique for BTA revascularization where the guidewire crosses, but no device can be advanced. This technique can be helpful in scenarios where failure to achieve success could result in limb loss. The BAT technique provides a solution in extremely challenging cases, enhancing technical success, improving outcomes and potentially preserving the limbs of patients who would otherwise face amputation, if not revascularized. The video shows the BAT technique performed with a support catheter under fluoroscopy: antegrate puncture of the DP, advancement of the support catheter over the wire, rendezvous of the guidewire in the catheter and subsequent externalization of the wire.
Effects of DLPFC tDCS Followed by Treadmill Training on Dual-Task Gait and Cortical Excitability in Parkinson’s Disease: A Randomized Controlled Trial
Authors: Wong Pei-Ling , Yang Yea-Ru , Huang Shih-Fong , Wang Ray-Yau 
Published: August 2024

Background Gait disturbances are exacerbated in people with Parkinson’s disease (PD) during dual-task walking (DTW). Transcranial direct current stimulation (tDCS) has been shown to exert beneficial effects on gait performance and cortical excitability in PD; however, its combined effects with treadmill training (TT) remain undetermined. Objective To investigate the effects of tDCS followed by TT on DTW performance and cortical excitability in individuals with PD. Methods Thirty-four PD participants were randomized to dorsal lateral prefrontal cortex (DLPFC) tDCS and TT group (DLPFC tDCS + TT group) or sham tDCS and TT group (sham tDCS + TT group) for 50 minutes per session (20 minutes tDCS followed by 30 minutes TT), 12 sessions within 5 weeks (2-3 sessions each week). Outcome measures included cognitive dual-task walking (CDTW), motor dual-task walking (MDTW), usual walking performance, cortical excitability, functional mobility, cognitive function, and quality of life. Results The DLPFC tDCS + TT group exerted significantly greater improvement in CDTW velocity ( P = .046), cadence ( P = .043), and stride time ( P = .041) compared to sham tDCS + TT group. In addition, DLPFC tDCS + TT group demonstrated a significant increase in resting motor threshold of stimulated hemisphere compared with sham tDCS + TT group ( P = .026). However, no significant differences between groups were found in MDTW performance and other outcomes. Conclusion Twelve-session DLPFC tDCS followed by TT significantly improved CDTW performance and decreased cortical excitability more than TT alone in individuals with PD. Applying DLPFC tDCS prior to TT could be suggested for gait rehabilitation in individuals with PD. Clinical trial registration number: Australian New Zealand Clinical Trials Registry ACTRN12622000101785