bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of chemical reaction on the Cattaneo–Christov heat flux model for viscoelastic flow over an exponentially stretching sheet
Authors: Sidahmed Abdelmgid O. M. , Salah Faisal , Viswanathan K. K. 
Published: July 2024

AbstractIn this article, the numerical solutions for the heat transfer flow of an upper-convected Maxwell fluid across an exponentially stretched sheet with a chemical reaction on the Cattaneo–Christov heat flux model have been investigated. Using similarity transformation, the controlling system of nonlinear partial differential equations was transformed into a system of ordinary differential equations. The resulting converted equations were solved numerically by a successive linearization method with the help of MATLAB software. A graphic representation was created to analyze the physical insights of the relevant flow characteristics. The findings were presented in the form of velocity, temperature, and concentration profiles. As the relaxation time parameter varied, the local Nusselt number increased. The thermal relaxation time was shown to have an inverse relationship with fluid temperature. Furthermore, the concentration boundary layer becomes thinner as the levels of the reaction rate parameter increase. The results of this model can be applicable in biological fluids and industrial situations. Excellent agreement exists between the analysis's findings and those of the previous studies.
Comparative analysis of geriatric hip fracture management outcomes in teaching and nonteaching hospitals in Jordan
Authors: Dawod Moh’d S. , Alswerki Mohammad N. , AR Altamimi Anas , Abu Hilal Mohammad , Albadaineh Ashraf , Saber Yaser , Alisi Mohammed S. , Al-Ajlouni Jihad 
Published: July 2024

AbstractHip fractures are common orthopedic injuries that have significant impacts on patients and healthcare systems. Previous studies have shown varying outcomes for hip fracture management in different settings, with diverse postoperative outcomes and complications. While teaching hospital settings have been investigated, no studies have specifically examined hip fracture outcomes in teaching hospitals in Jordan or the broader Middle East region. Therefore, the aim of this study was to investigate this important outcome. A cohort comprising 1268 patients who underwent hip fracture fixation from 2017 to 2020 was analyzed for nine distinct outcomes. These outcomes encompassed time to surgery, ICU admissions, perioperative hemoglobin levels, length of hospital stay, readmission rates, revision procedures, and mortality rates at three time points: in-hospital, at 6-months, and at 1-year post-surgery. The analysis of 1268 patients (616 in teaching hospitals, 652 in non-teaching hospitals) showed shorter mean time to surgery in teaching hospitals (2.2 days vs. 3.6 days, p < 0.01), higher ICU admissions (17% vs. 2.6%, p < 0.01), and more postoperative blood transfusions (40.3% vs. 12.1%, p < 0.01). In-hospital mortality rates were similar between groups (2.4% vs. 2.1%, p = 0.72), as were rates at 6-months (3.1% vs. 3.5%, p = 0.65) and 1-year post-surgery (3.7% vs. 3.7%, p = 0.96). Geriatric hip fracture patients in teaching hospitals have shorter surgery times, more ICU admissions, and higher postoperative blood transfusion rates. However, there are no significant differences in readmission rates, hospital stays, or mortality rates at various intervals.
Optimization scheduling of microgrid comprehensive demand response load considering user satisfaction
Authors: Wang Chaoliang , Li Xiong 
Published: July 2024

AbstractThe original load control model of microgrid based on demand response lacks the factors of incentive demand response, the overall satisfaction of users is low, the degree of demand response is low, the Time Of Use (TOU) price of peak-valley filling capacity is weak, and the peak-valley difference of load curve is large. Regarding the limitations of the current microgrid demand response model, this study further optimizes the flexible load control strategy and proposes a two-objective optimization model based on price and incentive. Meanwhile, the model is solved using an improved chaotic particle group algorithm. Finally, the microgrid load data were selected for simulation analysis. The simulation results showed that the comprehensive demand response of flexible control model proposed increased the overall satisfaction of users by 9.51%, the overall operating cost of microgrid suppliers decreased by 12.975/ten thousand yuan, the peak valley difference decreased by 4.61%, and the user demand response increased by 27.24%. The model effectively improves the overall profit of the supply side of the microgrid, improves the user satisfaction, and maximizes the linkage benefits of the supply and demand of the micro grid. In addition, the model effectively reduces the phenomenon of distributed power supply in the microgrid, and realizes the supply and demand matching of the whole load in the microgrid.
Early detection of low QRS voltage and its association with mortality in patients with sepsis
Authors: Na Soo Jin , Ko Ryoung-Eun , Chung Chi Ryang , Yang Jeong Hoon , Oh Dong Kyu , Lee Su Yeon , Park Mi Hyeon , Lee Haein , Lim Chae-Man , Suh Gee Young 
Published: July 2024

AbstractVarious electrocardiographic changes occur during sepsis, but data on the clinical importance of a low QRS voltage in sepsis are still limited. We aimed to evaluate the association between low QRS voltage identified early in sepsis and mortality in patients with sepsis. Between September 2019 and December 2020, all consecutive adult patients diagnosed with sepsis in the emergency room or general ward at Samsung Medical Center were enrolled. Patients without a 12-lead electrocardiogram recorded within 48 h of recognition of sepsis were excluded. In 432 eligible patients, 12-lead electrocardiogram was recorded within the median of 24 min from the first recognition of sepsis, and low QRS voltage was identified in 115 (26.6%) patients. The low QRS group showed more severe organ dysfunction and had higher levels of N-terminal pro-brain natriuretic peptide. The hospital mortality was significantly higher in the low QRS voltage group than in the normal QRS voltage group (49.6% vs. 28.1%, p < 0.001). Similarly, among the 160 patients who required intensive care unit admission, significantly more patients in the low QRS group died in the intensive care unit (35.9% vs. 18.2%, p = 0.021). Low QRS voltage was associated with increased hospital mortality in patients with sepsis.
Impact of previous pregnancy and BMI on cellular and serum immune activity from early to late pregnancy
Authors: Mealy Grace , Brennan Kiva , Killeen Sarah Louise , Kilbane Mark , Yelverton Cara , Saldova Radka , Groeger David , VanSinderen Douwe , Cotter Paul D. , Doyle Sarah L. , McAuliffe Fionnuala M. 
Published: July 2024

AbstractImmunological adaptions during pregnancy play a crucial role in healthy fetal development. Aberrant immune modifications however contribute to adverse pregnancy outcomes, which may be driven by maternal factors such as previous pregnancies and BMI. This secondary analysis of the MicrobeMom2 RCT investigates the changes to maternal inflammatory biomarkers derived from serum and stimulated peripheral blood mononuclear cells (PBMCs) during pregnancy, and the effects of previous pregnancies (parity) and BMI on maternal immune responses. Changes in immune and metabolic biomarkers from early (11–15 weeks’ gestation) to late (28–32 weeks’ gestation) pregnancy were compared using paired t-tests. Participants were then split by parity (nulliparous, parous) and BMI (BMI < 25, BMI > = 25), and the relationship between parity and BMI with immune biomarker levels was examined using independent t-tests, paired t-tests, ANCOVA, and linear regression. Equivalent non-parametric tests were used for skewed data. Recruited women (n = 72) were on average 31.17 (SD ± 4.53) years of age and 25.11 (SD ± 3.82) BMI (kg/m2). Of these, 51 (70.8%) had a previous term pregnancy. Throughout gestation, PBMC cytokines displayed contrasting trends to serum, with a dampening of immune responses noted in PBMCs, and enhanced production of cytokines observed in the serum. Significant decreases in PBMC derived TNF-α, IL-10 and IFN-γ were seen from early to late pregnancy. Serum C3, IL-17A, IL-6, TNF-α, CD163, GDF-15 and leptin increased throughout gestation. First pregnancy was associated with higher levels of leptin in late pregnancy, while parous women showed significant decreases in PBMC derived TNF-α, IL10, and IFN-γ with gestation. Differences in levels of C3, IL-17A, TNF-α, GDF-15 and leptin were observed across BMI groups. Overall, serum-derived cytokines exhibit contrasting levels to those derived from stimulated PBMCs. Maternal immune responses undergo significant changes from early to late pregnancy, which are influenced by parity and BMI. These differences aid our understanding as to why first-time mothers are at greater risk of placental disease such as pre-eclampsia and fetal growth restriction.
Enhanced SOC estimation of lithium ion batteries with RealTime data using machine learning algorithms
Authors: D. Obuli Pranav , Babu Preethem S. , V. Indragandhi , B. Ashok , S. Vedhanayaki , C. Kavitha 
Published: July 2024

AbstractAccurately estimating Battery State of Charge (SOC) is essential for safe and optimal electric vehicle operation. This paper presents a comparative assessment of multiple machine learning regression algorithms including Support Vector Machine, Neural Network, Ensemble Method, and Gaussian Process Regression for modelling the complex relationship between real-time driving data and battery SOC. The models are trained and tested on extensive field data collected from diverse drivers across varying conditions. Statistical performance metrics evaluate the SOC prediction accuracy on the test set. Gaussian process regression demonstrates superior precision surpassing the other techniques with the lowest errors. Case studies analyse model competence in mimicking actual battery charge/discharge characteristics responding to changing drivers, temperatures, and drive cycles. The research provides a reliable data-driven framework leveraging advanced analytics for precise real-time SOC monitoring to enhance battery management.
Comparative biological activity of palbociclib and ribociclib in hormone receptor-positive breast cancer
Authors: Lorman-Carbó Natàlia , Martínez-Sáez Olga , Fernandez-Martinez Aranzazu , Galván Patricia , Chic Nuria , Garcia-Fructuoso Isabel , Rodríguez Adela , Gómez-Bravo Raquel , Schettini Francesco , Blasco Paula , Castillo Oleguer , González-Farré Blanca , Adamo Barbara , Vidal Maria , Muñoz Montserrat , Perou Charles M. , Malumbres Marcos , Gavilá Joaquín , Pascual Tomás , Prat Aleix , Brasó-Maristany Fara 
Published: July 2024

AbstractThis study examines the biological effects of palbociclib and ribociclib in hormone receptor-positive breast cancer, pivotal to the HARMONIA prospective phase III clinical trial. We explore the downstream impacts of these CDK4/6 inhibitors, focusing on cell lines and patient-derived tumor samples. We treated HR+ breast cancer cell lines (T47D, MCF7, and BT474) with palbociclib or ribociclib (100 nM or 500 nM), alone or combined with fulvestrant (1 nM), over periods of 24, 72, or 144 h. Our assessments included PAM50 gene expression, RB1 phosphorylation, Lamin-B1 protein levels, and senescence-associated β-galactosidase activity. We further analyzed PAM50 gene signatures from the CORALLEEN and NeoPalAna phase II trials. Both CDK4/6 inhibitors similarly inhibited proliferation across the cell lines. At 100 nM, both drugs partially reduced p-RB1, with further decreases at 500 nM over 144 h. Treatment led to reduced Lamin-B1 expression and increased senescence-associated β-galactosidase activity. Both drugs enhanced Luminal A and reduced Luminal B and proliferation signatures at both doses. However, the HER2-enriched signature significantly diminished only at the higher dose of 500 nM. Corresponding changes were observed in tumor samples from the CORALLEEN and NeoPalAna studies. At 2 weeks of treatment, both drugs significantly reduced the HER2-enriched signature, but at surgery, this reduction was consistent only with ribociclib. Our findings suggest that while both CDK4/6 inhibitors effectively modulate key biological pathways in HR+/HER2- breast cancer, nuances in their impact, particularly on the HER2-enriched signature, are dose-dependent, influenced by the addition of fulvestrant and warrant further investigation.
Modelling the fundamental diagram of traffic flow mixed with connected vehicles based on the risk potential field
Authors: Yin Jiacheng , Cao Peng , Li Zongping , Li Linheng , Li Zhao , Li Duo 
Published: July 2024

AbstractThe fundamental diagram (FD) of traffic flow can effectively characterize the macroscopic characteristics of traffic flow and provide a theoretical foundation for traffic planning and control. The rapid development of connected vehicles (CVs) has led to changes in traffic flow characteristics. However, research on the FD of traffic flow involving CVs and non‐connected vehicles (NCVs) is still in its early stages. Most FDs do not well characterize the motion behaviour of different vehicles, nor do they study the interaction between mixed vehicles. Therefore, in this study, the FD of mixed traffic flows (i.e. with CVs and NCVs) was constructed within a unified framework. First, the car‐following behaviours of CVs and NCVs were modelled based on risk potential field theory. Subsequently, the FD of mixed traffic flows was derived based on the relationship between car‐following behaviour and the macroscopic traffic flow under steady‐state conditions. To validate the model, rigorous verifications were conducted via numerical experiments using the Monte Carlo method. The results indicate significant agreement between the scatter plots obtained from the experiments and the theoretical curves for different penetration rates. The proposed FD has a unified framework and a more rigorous mathematical structure.
Symptomatic Cerebellar Cyst Formation after Foramen Magnum Meningioma Removal: A Case Report
Authors: Hanai Sho , Yanaka Kiyoyuki , Onuma Kuniyuki , Nakamura Kazuhiro , Kajita Michihide , Aiyama Hitoshi , Ishikawa Eiichi 
Published: July 2024

Abstract
Background Symptomatic cerebellar cyst formation after surgery is rare and the mechanism remains unknown. We describe a cerebellar cyst that gradually expanded, becoming symptomatic, after the removal of a foramen magnum meningioma and discuss the mechanism of cyst formation.
Case Description A 76-year-old woman with a tumor at the foramen magnum was treated by posterior fossa craniotomy and C1 hemilaminectomy. The patient suddenly developed cerebellar symptoms and consciousness disturbance approximately 1 week into an otherwise good postoperative course. Imaging showed a subcutaneous pseudomeningocele in the occipital region and cerebellar cyst formation. After resolution by fenestration of the cerebellar cyst and duraplasty, the patient's symptoms gradually improved. No tumor or cerebellar cyst recurrence has been detected in over 5 years since the surgery.
Conclusion Postoperative pseudomeningocele appeared crucial for cerebellar cyst formation. Postoperative development of symptomatic cerebellar cysts is rare but should be recognized as a serious, sometimes life-threatening, postoperative complication of posterior fossa surgery.
The Efficiency of an Advanced Hybrid Closed Insulin Pump in Patients with Type 1 Diabetes for Improved Blood Glucose Control
Authors: Owaydah Amal , Abouglila Kamal , Liloglou Triantafillos 
Published: July 2024

Abstract
Background Diabetes technology, especially advanced hybrid closed-loop (AHCL) systems, is rapidly advancing, offering improved glycemic control, reduced hypoglycemia, and reduced treatment burden for patients with type 1 diabetes (T1D). This study aimed to evaluate the clinical efficiency of an AHCL system—the Medtronic MiniMed 780G insulin pump combined with continuous glucose monitoring—among individuals with T1D in real-world clinical settings.
Methods In an observational retrospective study, we identified a cohort of 41 patients (mean age, 47.1 ± 13.7 years; T1D duration, 23.6 ± 13 years; 73.2% female) previously using an insulin pump or those on multiple daily insulin injections, currently using the AHCL system for at least 6 months. Primary outcomes were the changes of the following parameters, before AHCL initiation and at 6 months after treatment; (1) time in range (TIR): time with glucose levels in the range of 70 to 180 mg/dL, (2) time below range (TBR): time with glucose levels below 70 mg/dL, and (3) time above range (TAR): time with glucose levels above 180 mg/dL.
Results Data analysis from 41 patients showed a significant 16.5% ± 13.8% increase in TIR (from 56.6 ± 17.9 to 73.1 ± 10.6%, p < 0.001). Both TBR and TAR decreased by 2.9 ± 4.8% (p = 0.004) and 13.6 ± 16.4% (p < 0.001), respectively. Mean glucose concentration, coefficient of variation, and glucose management indicator significantly improved.
Conclusion The AHCL system effectively improved glucose control regarding TIR, TBR, and TAR. Enhanced glycemic control metrics highlight the potential for wider adoption of AHCL technology.
Computational analysis of entropy generation optimization for Cu–Al2O3 water-based chemically reactive magnetized radiative hybrid nanofluid flow
Authors: Govind  , Sharma Pooja , Sharma B. K. , Gandhi Rishu , Almohsen Bandar , Pérez Laura M. 
Published: July 2024

This study aims to analyze the mass transfer and entropy generation in the flow system of chemically reactive, thermal radiative hybrid nanofluids (Al2O3/Cu with H2O as base fluid) flow across flat stretching porous surfaces in the presence of viscous dissipation and transverse magnetic field. The governing partial differential equations are converted into a set of ordinary differential equations by applying a group of self-similarity transformations. The resulting differential equations are solved using the Bvp4c technique in MATLAB. The impact of several physical parameters has been examined the velocity, heat, and mass transfer components of the fluid. To optimize the complete heat transfer process, the consequences of all physical parameters are discussed on entropy generation and Bejan number and presented graphically. It is observed that velocity increases with the increase in magnetic parameter M because pressure force dominates over Lorentz force, temperature increases with the rise of Ec, concertation reduces with the enhancement of chemical reaction parameter delta, and the Bejan number decreases with the increase in Br; however, reverse phenomena are observed with increasing the value of the magnetic number and entropy increases with the rise of magnetic parameter M. Due to the increase in magnetic parameter M, drag force is accelerated, which leads to increase in entropy, With an increment in Pr and Ec, the heat exchange rate declines although the skin friction coefficient and mass transfer remain constant. There are several significant applications of the study of thermal analysis of hybrid nanofluid flows in numerous mechanical processes, such as extrusion or metal manufacturing processes, heat transportation in biological tissues, cooling of electric devices, high-size refrigeration, hydroelectric dams, and fuel systems.
Language variation and temporary norm development in intercultural interactions
Authors: Kecskes Istvan 
Published: July 2024

Abstract
The paper argues that interlocutors in intercultural interactions rely mainly on co-constructed temporary norms rather than on codified norms of the target language. There is a complex interplay of codified and emergent norms that drives interaction. Temporary norms emerge through temporary communicative extension of the system (TCE) that are expressions, chunks and utterances that violate the existing relatively definable norms and conventions of target language use, but still make sense in actual situational contexts and can be considered possible outputs of the English language system. TCEs function as building blocks for temporary norms, and they can also be building blocks in common ground development. The paper demonstrates these functions through examples in intercultural interactions.
Enhancing PV-TEG performance and water cooling on TEG with serial different configurations
Authors: Rahman Y A , Masarrang M , Sau K M T , Iskandar  , Basri  , Mustofa  
Published: July 2024

Abstract
Palu, which is crossed by the equator, gets enough sunlight intensity to be used as a renewable energy source for generating electricity. This paper is an investigative study on the performance of a 50 Wp solar panel (PV) combined with a thermoelectric generator (TEG) module as a heat sink and electric energy generator. The SP1848-27145 SA TEG module is placed on the lower surface of the PV and covered with aluminium sheets between the PV and the TEG. The cold side of the TEG module is provided with circulating water cooling to maintain the temperature on the cold side of the TEG. There are 5 TEG modules arranged in series with 2 different configuration variations between the PV and the aluminium plate. One PV panel was left without a TEG module during testing to compare the results with adding a TEG module to 2 PV panels. In total, there were 3 PV panels and 10 TEG modules which were tested simultaneously for 3 days on the Tadulako University campus. All voltage, PV-TEG current parameters, and solar intensity are recorded using standard measuring instruments. As a result, the temperature of the upper surface of the PV is below a safe 60 °C, while the temperature on the lower surface of the PV which is also the temperature of the hot side of the TEG decreases significantly compared to that without using TEG. The TEG rectangle configuration generates 26% greater output power compared to the square one. An output voltage stabilizer is needed on the PV to get better power and modification of the TEG stack model in further studies.
Development of smart Indonesian horticultural farmers learning prototype application “b-horti”
Authors: Ngatindriatun  , Tjhin V U , Alfarizi M , Hanum R K , Firmansyah A A 
Published: July 2024

Abstract
Horticulture is one of Indonesia’s leading agricultural sub-sectors that can be developed by the community in all situations, including narrow land. However, the horticultural sector still needs to be discovered in its incredible potential due to constraints on competency development channels. This study aims to increase the empowerment and competence of farmers by optimizing the development of technology and network information systems related to the cultivation of horticultural crops at the farmer level—research and development methods used for this study which divided into several stages. Data collection was carried out in the first stage to analyze the needs of horticultural farmers so that the application design could meet the needs of farmers. Design planning implemented in the second stage produces use case diagrams, activity diagrams, and user interface designs that describe the interface, operation flow, and application usage. The B-Horti application is designed with excellent features, including EduTan, Jejaring B-Horti, PasarHorti, etc. Evaluation of the application prototype design is carried out at the last stage to find out and review the compatibility of the application prototype with user needs and multimedia characteristics from the analysis results. The prototype was evaluated by multimedia experts, agriculture academics, and horticultural farmers around the researcher with seven question indicators. The results of the prototype design evaluation show the urgency of developing further stages of this application with consideration of the needs and valuable life of the application.