bluuebunny/crossref_metadata_2025_split huggingface dataset:
Patients' Perception of Missed Nursing Care in a Tertiary Hospital: A Cross‐Sectional Study
Authors: Sarpong Afia Achiaa , Towell‐Barnard Amanda , Gent Lucy , Afrifa‐Yamoah Ebenezer , Arabiat Diana 
Published: February 2025

ABSTRACTAimsTo identify types of patient‐reported missed nursing care and adverse events and identify the factor associated with missed care in a Western Australian tertiary hospital.BackgroundResearch in the domain of missed nursing care has established the association between missed nursing care and unsafe patient outcomes. However, there is a paucity of evidence on patient perception of missed nursing care and associated factors.DesignCross‐sectional study.MethodA study of inpatients in a tertiary teaching hospital in Western Australia was carried out. Ninety‐eight patients admitted in 16 medical and surgical wards were sampled. The patient MISSCARE survey was used to capture patient‐reported types of missed care, prevalence of adverse events and the association between missed care, unit type, demographic characteristics and patient health problems. Descriptive and logistic analysis were performed using SPSS.FindingsThe most frequently reported missed nursing care activities included mouth care (63%), ambulation (35%), helping patient out of bed into a chair (31%), informing patient about tests or procedures (29%) and considering patient opinion (27%). The majority of reported missed care activities were from basic care domain followed by communication. The most common adverse events reported were intravenous infusion leaking into skin, intravenous fluid running dry, falls and development of pressure ulcer. Significant association was observed between missed nursing care and patient age.DiscussionThe findings of this study showed significant level of patient‐reported missed nursing care particularly in the domain of basic care. Although this study's limitations, including its small sample size and potential response bias, warrant caution in generalising the findings, the insights gained provide a valuable foundation for future research aimed at improving patient care.ConclusionFindings provide valuable insight about patient's perception of missed care and inform the need for effective interventions to reduce unsafe outcomes related to missed nursing care.Relevance to Clinical PracticeHealthcare systems need to make necessary efforts to ensure that patients receive the right amount of care needed to maintain and promote safe hospitalisation outcomes.Reporting MethodThe study was reported according to the STROBE guidelines.Patient or Public ContributionThe development of this study protocol, data collection, analysis and interpretation of results were carried out through a collaborative effort between patients, families and the research team.
Localization Through Coordination? Implementing the Humanitarian‐Development‐Peace Nexus in the Democratic Republic of the Congo
Authors: Desrosiers Marie‐Eve , Swedlund Haley J. 
Published: February 2025

ABSTRACTAs a global concept and initiative, the Humanitarian‐Development‐Peace Nexus (HDPN) aims to improve integration across the traditionally siloed humanitarian, development, and security sectors, while foregrounding the involvement of local actors. Using original empirical data on the implementation of the HDPN in the Democratic Republic of the Congo (DRC), we show how and why the approach has not delivered substantive localization in the Congolese context. In the DRC, nexus implementation has replicated gaps and inequalities between the national and provincial levels. This manifests in two ways: a persistent functional disconnect between work at the national and the provincial levels, and a substantive disconnect in the form of an inability of national‐level actors to leverage an organic nexus already found at the provincial level. Our analysis raises important questions about the compatibility of coordination and substantive localization.
Ag‐Deposited Pitch‐Based Carbon Fiber/Silicone Composites With Enhanced Thermal Conductivity Through Reducing Interfacial Thermal Resistance
Authors: Shen Jingbo , Feng Yakai 
Published: February 2025

ABSTRACTThermal interface materials are crucial for the thermal management of modern electronic devices. The thermal conductivity of polymer‐based composites, as the widely used thermal interface materials, is still limited by the high interfacial thermal resistance between the polymer matrix and the filler. Herein, pitch‐based carbon fibers co‐modified with silane coupling agent and Ag nanoparticles were developed and used as thermally conductive fillers to prepare silicone composites with the purpose of improving interfacial compatibility and reducing interfacial thermal resistance. Under scanning electron microscope observation, the modified carbon fibers dispersed uniformly, and they were adhered to by a number of Ag nanoparticles. The thermal conductivity of the silicone composite with a 20 wt% filling amount of modified carbon fibers reached up to 1.624 W m−1 K−1, which was 1.46 times higher than that of the unmodified carbon fiber filled silicone composite. The silicone composite with a 20 wt% filling amount of modified carbon fibers also exhibited a relatively high heat transfer rate and excellent mechanical properties. The electrical insulation and dielectric properties of silicone composites filled with modified carbon fibers also satisfied the requirements for the use of thermal interface materials. This approach provided an effective strategy for the development of thermal interface materials with high thermal conductivity in the thermal management field.
Experimental investigation of the low velocity impact behavior and residual compressive strength of a novel Double–Double layup composite laminates
Authors: Chang Zhengping , Gao Yazhi , Chen Jingyu , Zhao Jialong , He Liang , Zhao Yang , Wang Zhongqi 
Published: February 2025

AbstractDouble–Double (DD) laminates, a novel composite layup design, have attracted much attention due to its flexible stacking sequence of [±Φ/±Ψ]rT and greater design flexibility. DD laminates exhibited advantages in industrial applications by simplifying stacking design, reducing weight, and enhancing manufacturing efficiency. However, the research on the impact resistance of DD laminates is still limited. Thus, this paper focused on the impact resistance and compressive properties after impact of DD laminates. In this study, four controlled trials composed of the DD laminates and its converted legacy quad laminates (LQL) were designed. Then, low velocity impact (LVI) tests and compression after impact (CAI) tests were carried out to obtain impact response curves, while ultrasonic C‐scan was applied to conduct damage evaluation. DD laminates showed remarkable advantages over LQL laminates in impact resistance. The residual compressive strength (RCS) of DD converted from QI and Hard increased by 4.36%–28.99%. The maximum reduction of delamination damage projection area (DDPA) for the impacted DD was up to 63.02% compared to that of LQL. It was particularly noteworthy that flipped DD exhibited significant differences in impact resistance, which differed from the LQL ones.Highlights
The research on impact resistance of LQL and DD laminates was expanded.
DD laminates reduced the DDPA after LVI.
The dent depth of DD converted from Soft and Hard1 types decreased.
The front and reverse impacts of DD laminates were compared.
DD converted from QI and Hard could improve the RCS.
Single screw extrusion of long discontinuous fiber‐reinforced polymers: Pellet motion and heat transfer
Authors: Kapre Vasudha , Barocio Eduardo , Pipes R. Byron 
Published: February 2025

AbstractSingle screw extrusion is widely used in material pre‐compounding, extrusion additive manufacturing, and injection molding. A single screw extruder has three stages—the solid conveying zone, the transition zone, and the melt‐conveying zone. In starve‐fed extrusion, the screw channels are partially filled, and melting cannot be analyzed by traditional plug‐flow melting models. However, understanding individual pellet motion and melting is an essential precursor to modeling pellet deformation and fiber length attrition in the transition and melt‐conveying zones. Therefore, a sequentially coupled framework has been developed to capture individual pellet trajectories and their melting in a single screw extruder. The discrete element method has been used to study motion of long‐discontinuous fiber‐reinforced pellets which are represented as multi‐spheres. Individual pellet melting is captured in a static heat‐transfer analysis with dynamic boundary conditions based on the contact information obtained from pellet interactions with its surroundings. Results indicate a translational‐conveying motion followed by a rotational‐conveying motion of individual pellets as they move along the screw. The rotational‐conveying motion coincides with an increase in screw pitch and corresponds to the highest rate of pellet melting. Increasing screw rotation speed reduced the residence time causing insufficient pellet melting. Decreasing the feeding rate did not significantly affect the residence time but resulted in improved melting through increased thermal contacts. Melting is initiated locally on the pellet surface due to thermal contacts and proceeds radially inward. In this process, pellets first experience a molten surface shell before the core reaches melt temperature.Highlights
Multi‐sphere representation of LDF reinforced pellets.
A discrete element model to capture pellet flow in a single screw extruder.
Individual pellet trajectories extracted from single screw extrusion.
A sequentially coupled finite‐element model to study LDF pellet heat transfer.
Study of screw speed and feeding rate on average pellet melting behavior.
The physiological role of macrophages in reproductive organs
Authors: Yoshino Osamu , Ono Yosuke 
Published: February 2025

AbstractBackgroundMacrophages are essential immune cells critical to reproductive physiology. They regulate key processes such as follicular development, ovulation, and luteinization in the ovaries. Macrophages are also involved in endometrial remodeling, immune tolerance, and placentation in the uterus.MethodsThis review examined the biological characteristics of macrophages and their role in ovarian, uterine, and fallopian tube physiology. It focused on findings from both animal and human studies to provide a comprehensive understanding of macrophage functions.Main FindingsIn the ovaries, M1 macrophages play a role in folliculogenesis and ovulation through the inflammatory and angiogenic pathways. Macrophages also maintain the corpus luteum and vascular integrity. In the uterus, macrophages regulate tissue repair and remodeling during the menstrual cycle and play a critical role in implantation by maintaining immune tolerance and supporting decidualization. Dysregulation of the M1/M2 balance can cause implantation failure. In the fallopian tubes, macrophages mediate tissue repair and immune responses. Macrophage polarization dynamically adapts to physiological and pathological conditions in all reproductive organs highlighting the functional plasticity of these cells.ConclusionMacrophage polarization and functions are pivotal in maintaining reproductive health. Hence, understanding the role of macrophages in various reproductive organs provides a foundation for developing new therapies.
Phytochemical‐Mediated Copper Oxide Nanoparticles Using Cheilocostus speciosus and Gardenia gummifera: Design, Synthesis, and Antimicrobial Evaluation Through In Silico and In Vitro Approaches
Authors: Maind Rohit , Halder Shubhajit , Bhat Ajmal R , Bhattacharya Doyel , Alam Manawwer , Wahab Rizwan , Ahmed Sumeer , Sadaf Azmiya 
Published: February 2025

AbstractIn this study, we synthesized copper oxide nanoparticles using leaf extracts of two Indian medicinal plants, Cheilocostus speciosus (CS) and Gardenia gummifera (GG), for the first time. The environmentally sustainable synthesis of CuO NPs from Cu(NO3)2 uses phytochemical capping and stabilizing properties. UV‐DRS, X‐ray diffraction (XRD), Fourier transform‐infrared (FT‐IR), XPS, SEM‐EDS, and TEM‐SAED confirmed CS‐CuO and GG‐CuO NP structure and morphology. UV‐DRS diffuse reflectance spectra show two absorption bands at 218–350 and 406–554 nm. Functional group studies of CS‐CuO and GG‐CuO NPs were done using FT‐IR. XRD patterns of CS‐CuO and GG‐CuO NPs show monoclinic phases and average sizes of 4.62 and 11.85 nm. Morphological studies used SEM‐EDX and TEM‐SAED. Biosynthesized CuO‐NPs were tested against Gram‐negative, Gram‐positive, Aspergillus niger, and Candida albicans. CS‐ and GG‐CuO NPs inhibited Escherichia coli and Staphylococcus aureus with 18‐ and 16‐mm zones, respectively. Bioinspired CuO NPs kill many bacterial strains, making them useful in nanobiotechnology. Molecular modelling determined the S. aureus nucleoside diphosphate kinase receptor's bonding affinity and inhibition probability with phytochemicals present in the leaf extract. In silico pharmacokinetics studies and prediction of physiochemical parameters predicted the drug‐likeness and non‐toxic behavior of the phytochemicals. Overall, current research demonstrates an environmentally sustainable synthesis of CuO nanoparticles utilizing leaf extracts from CS and GG, providing a sustainable and non‐toxic alternative to traditional methods. The antimicrobial efficacy of these nanoparticles against bacterial and fungal strains addresses the growing demand for novel strategies to counter microbial resistance. In addition, in silico molecular modelling and pharmacokinetics studies further emphasis the drug‐likeness and safety of phytochemicals, underscoring their significance in nanobiotechnology and drug development. This multidisciplinary approach illustrates the extensive relevance and significance of our efforts in promoting green chemistry and antimicrobial strategies.
Electrochemical CO2 Reduction Technology Toward Practical Application: Status Quo and Challenges
Authors: Cheng Zi‐Ye , Lu De‐Yong , Chen Jia‐Yi , Zhang Wei , Li Jia‐Xin , Yang Yan , Yu Feng‐Ping , He Fan , Qi Zhi‐Fu 
Published: February 2025

AbstractElectrochemical CO2 reduction (denoted as ECO2R) technology is expected to transform greenhouse gas CO2 into a range of fuels and chemicals combined with renewable electricity. A wide range of fundamental research has been dedicated to the clarification of reaction mechanisms and developing the catalyst materials, which have significantly facilitated the level of ECO2R technology. Nevertheless, ECO2R technology still encounters limitations such as low CO2 utilization efficiency and insufficient selectivity to high‐value products. Addressing these challenges is crucial for the technology to be implemented in practical applications. In an electrolysis system, the electrolyzer represents the core component of the system and the primary reaction site. Therefore, the composition and structure of the electrolyzer will directly affect the reaction performance. This review begins by outlining the recent progress of the ECO2R technology at a large‐scale level, followed by a comprehensive analysis of the industrial ECO2R electrolyzer configuration, including detailed considerations of the electrode, gas diffusion layer, and membrane in the electrolyzer. Finally, we elucidate the remaining challenges associated with the industrialization of this technology and offer suggestions for advancing it.
Efficient Single‐Pot Synthesis of Thiazole Derivatives: A Synoptic View
Authors: N Ramyashree , Kumar S Lokesh , Tabassum Sumaiya , Chundattu Sony J , Govindaraju Santhosh 
Published: February 2025

AbstractIn recent years, heterocyclic compounds have gained significant interest due to their tremendous application in the medicinal, optical, and biological fields. Among them, thiazole is an important heterocycle containing nitrogen‐ and sulfur‐ in the ring, which stands out as the best for its pharmacological activity. One of the best routes to synthesize these molecules is through multicomponent reactions. Being a sustainable methodology, it gives insights into generating an extensive range of biologically active molecules. This review focuses on the significance of three‐component and four‐component syntheses of thiazole under various conditions from the year 2000 to late 2024, which are particularly important due to their ability to produce thiazole derivatives with good yields.
Biomass Derived Hybrid Activated Carbon/Iron Oxide Composite for Photodegradation of Methylene Blue Upon Visible Light
Authors: Ullah Sami , Kumar Ome Parkash , Ali Rashid , Riaz Nagina Naveed , Ahmad Ashfaq , Tufail Muhammad Khurram , Muhammad Niaz , Rehman Aziz ur , Shah Syed Shoaib Ahmad , Nazir Muhammad Altaf 
Published: February 2025

AbstractThe calcination and coprecipitation processes were combined to make semiconductor‐based AC@Fe3O4, which was then used to investigate the photodegradation of methylene blue (MB) dye. The crystallite size of composite AC@Fe3O4 was computed as 16.73 nm. The pristine Fe3O4, activated carbon, and composite AC@Fe3O4 witness sufficient photodegradation efficiency of MB dye. The UV–visible spectrum of AC@Fe3O4 manifested the presence of band edges in the UV–visible region of the spectrum, revealing marvelous capability towards catalytic degradation in the long range of radiation. The structural defects and disparity in the charge transfer produced by integrating Fe3O4 and AC encouraged the absorption of visible light. The effective material AC@Fe3O4 showed ascendant photodegradation of 10 mgL−1 MB dye up to 94.6% in 140 min at a kinetic rate of 0.025 min−1. The results of the reusability test demonstrated that AC@Fe3O4 may be used repeatedly to photodegrade MB dye with only a slight drop in photodegradation effectiveness. The quenching experiment demonstrated the specific impact of radicals on the photodegradation of MB dye. The MB dye degradation mechanism underscores reactive oxygen species (ROS), primarily responsible for the degradation process. Based on the findings of current study, it can be concluded that AC@Fe3O4 is a potential solid photocatalyst for the photodegradation of dyes in wastewater.
Metal‐organic Frameworks Containing Homophthalic Acid and Imidazole Ligands as Fluorescent Probes for the Detection of Fe3+, CrO42−, and Cr2O72− Species in Aqueous Solutions
Authors: Cao Yun , Yuan Ke‐Xin , Zhou Shuo , Wang Yan 
Published: February 2025

AbstractIn this paper, a new metal‐organic framework, namely, [Zn(LBIX)(HPA)2]n (1) (LBIX = 4,4′‐bis((1H‐imidazol‐1‐yl)methyl)‐1,1′‐biphenyl, H2HPA = Homophthalic acid) was synthesized and characterized, which can be used as a fluorescent probe for the detection of harmful heavy metals in water. The single‐crystal structure results indicated that complex 1 is composed of two‐dimensional planar structures, which are connected by intermolecular hydrogen bonding and stacked to form a 3D supramolecular structure. The fluorescence properties and potential for detecting heavy metal ions in water were also studied by anion and cationic sensing experiments. Complex 1 exhibited low detection limit (LOD) in Fe3+, CrO42−, and Cr2O72− fluorescence sensing experiments. Complex 1 also has good recyclability and stability in the detection of analytes. The possible mechanism of fluorescence burst was analyzed and the selectivity and sensitivity of complex 1 were further evaluated in competition experiments.
A Label‐Free Fluorescence Aptasensor for the Detection of Ciprofloxacin in Actual Samples
Authors: Kong Wei‐Chuang , Wu Xing‐Hu , Li Chen‐Chen , Hua Wen‐Xue , Dong Xiao‐Yi , Meng Ya‐Li , Jia Xiao‐Juan , Wei Dong , Kang Yan‐Fei 
Published: February 2025

AbstractCiprofloxacin (CIP) is a third‐generation fluoroquinolone antibiotic widely used in veterinary and clinical settings. However, overuse can result in the development of quinolone‐resistant pathogens, posing risks to ecosystems and human health. In this work, we developed the fluorescence method for detecting CIP based on FRET (Förster Resonance Energy Transfer) between the fluorescein isothiocyanate (FITC) fluorescent dye and graphene oxide (GO). The aptamer was immobilized on the GO surface through π–π stacking interaction preventing effectively FITC from coming into contact GO to result in strong fluorescence. Upon the addition of CIP, the aptamer combined preferentially to the CIP and leaded to the release of GO, which made the FITC to be close to GO, leading to significant quenching of FITC due to FRET. The fluorescence intensity exhibited a consistent reduction in proportion to the CIP concentrations with 2.99–800 nM. Under the same conditions, the limit of detection was calculated to be 2.99 nM. The sensor can be used for the detection of CIP in serum, urine, and milk with spiked recoveries ranged from 99.65%–100.97% and relative standard deviations ranging from 0.17%–1.49%, which provided a detection tool for food safety and control standards.
Recent Advances in the Application of Selectfluor as a Versatile Reactant in Organic Photo‐ and Electrochemical Synthesis
Authors: Yuan Dan , He Yongli , Sun Xiaoqiang , Li Zhengyi , Li Bijin , Yang Ke 
Published: February 2025

AbstractSelectfluor [1‐chloromethyl‐4‐fluoro‐1,4‐diazoniabicyclo‐[2.2.2]octane bis(tetrafluoroborate)] is a versatile reagent in organic synthetic chemistry. As a renowned electrophilic fluorinating agent, Selectfluor is widely acknowledged as a crucial source of fluorine for various fluorination reactions. Moreover, it is employed as a “fluorine‐free” reagent comprising a transition metal oxidant, a fluorine anion, and a radical initiator; achieving various other organic transformations. Notably, Selectfluor can also serve as an amine or a methylene source in organic synthesis. Recently, there has been growing interest in the application of Selectfluor as a versatile reactant in photo‐ and electrochemistry. In this review, a comprehensive overview of Selectfluor's application as a fluorine or amine source in organic photo‐ and electrochemical strategies over the past decade, is provided.
Dual Metal Nanoflower Oxygen Pump Microneedles Based on Cuproptosis and STING Pathway Activation for Cancer Immunotherapy
Authors: Tao Jiaojiao , Dong Yu , Wang Bingjie , Wang Teng , Zhang Aijia , Li Shuang , Chen Rui , Su Yanguo , Jiang Tianze , Zhao Xia 
Published: February 2025

AbstractImmunotherapy is a promising new approach for tumor treatment. However, its clinical application is hindered by insufficient immunogenicity, hypoxia, and immunosuppressive tumor microenvironment (TME). Here, oxygen pump microneedles (OPMNs) loaded with zinc‐doped copper sulfide nanoflowers (ZCS NFs) and PD‐L1 small interfering RNA (siPD‐L1) (OPMNs‐ZCS@siPD‐L1) are developed for boosting tumor immunotherapy. OPMN‐ZCS@siPD‐L1 enhances tumor immunogenicity through ZCS NFs by inducing cuproptosis, reverses TME through siPD‐L1, and promotes drug penetration, and ameliorates hypoxia through oxygen bubbles. More importantly, cuproptosis‐induced mitochondrial DNA (mtDNA) together with Zn2+ co‐activate the STING pathway, triggering a robust immune response. OPMN‐ZCS@siPD‐L1 increases the sensitivity to cuproptosis and induces immunogenic cell death (ICD) in vivo and in vitro, which significantly inhibits tumor progression and metastasis. The novel strategy of “increasing the throttle” (cuproptopsis‐mediated STING activation & ICD effect) combined with “releasing the brake” (PD‐L1 inhibition & hypoxia improvement) provides a new approach for enhancing percutaneous tumor immunotherapy.