bluuebunny/crossref_metadata_2025_split huggingface dataset:
Contradictions at Work: A Critical Review
Authors: McGovern Patrick 
Published: February 2013

Despite significant achievements in empirical research, considerable unease exists about the lack of conceptual and theoretical debate within the sociology of work. One potentially significant problem is the uncritical use of concepts that have their origins in Marxism and purport to explain the essential features of the employment relationship. Using evidence from a systematic review of four highly ranked British journals I chart the growing influence of the concept of contradiction, notably within the labour process perspective where it has become a key concept, especially in relation to the problem of labour control. In spite of its popularity, I argue that the concept contains two sets of flaws. The first set, which relate to its utility as a concept, include problems of logic, differentiation and operationalization. The second set relate to the substantive use of the concept, especially its dependence on supporting assumptions, and its expectation of social change. The article concludes by calling for a moratorium on further usage.
Challenges and Success of Recruiting and Retention for a Culturally Tailored Diabetes Prevention Program for Adults of Mexican Descent
Authors: Vincent Deborah , McEwen Marylyn M. , Hepworth Joseph T. , Stump Craig S. 
Published: February 2013

Purpose The purpose of this article is to describe methods used to recruit and retain high-risk, Spanish-speaking adults of Mexican origin in a randomized clinical trial that adapts Diabetes Prevention Program (DPP) content into a community-based, culturally tailored intervention. Methods Multiple passive and active recruitment strategies were analyzed for effectiveness in reaching the recruitment goal. Of 91 potential participants assessed for eligibility, 58 participated in the study, with 38 in the intervention and 20 in the attention control group. The American Diabetes Association Risk Assessment Questionnaire, body mass index, and casual capillary blood glucose measures were used to determine eligibility. Results The recruitment goal of 50 individuals was met. Healthy living diabetes prevention presentations conducted at churches were the most successful recruiting strategy. The retention goal of 20 individuals was met for the intervention group. Weekly reminder calls were made by the promotora to each intervention participant, and homework assignments were successful in facilitating participant engagement. Conclusions A community advisory board made significant and crucial contributions to the recruitment strategies and refinement of the intervention. Results support the feasibility of adapting the DPP into a community-based intervention for reaching adults of Mexican origin at high risk for developing diabetes.
Systematic review of atomoxetine data in childhood and adolescent attention-deficit hyperactivity disorder 2009–2011: Focus on clinical efficacy and safety
Authors: Bushe Chris J , Savill Nicola C 
Published: February 2013

Background: Clinicians obtain critical prescribing knowledge from clinical papers and review articles. This is the first published systematic review of clinical atomoxetine data covering 2009–2011. Objective: We aim to update clinicians on current clinical atomoxetine data with specific reference to time of onset of efficacy and maximal efficacy. These data may allow critical analysis of comparative efficacy between atomoxetine and stimulant medications. Methods: A formal systematic review of atomoxetine data from January 2009–June 2011 was conducted. The search term used was “atomoxetine” in the English language. The search yielded 747 citations from which 106 are clinical data. This paper includes clinical efficacy and safety data and excludes quality-of-life and review papers. Results: Atomoxetine has an onset of action within 4 weeks (possibly within 1 week in subsequent responders) but requires at least 12 weeks for full response to be demonstrated. Treatment-naïve cohorts (6–12 weeks) report effect sizes of 0.6–1.3. Using minimum 6-week clinical trial criteria, atomoxetine may demonstrate similar efficacy to methylphenidate comparing reduction in core ADHD symptoms in meta-analysis, although the diversity of the data makes interpretation complex. From epidemiological databases, cardiovascular and suicide-related events were similar to those seen in patients taking methylphenidate. Conclusions: Incremental response time to atomoxetine should be considered in the design of future comparative efficacy trials.
Altered pain perception in children with chronic tension-type headache: Is this a sign of central sensitisation?
Authors: Soee Ann-Britt L , Thomsen Lise L , Kreiner Svend , Tornoe Birte , Skov Liselotte 
Published: February 2013

Aim The aim of this article is to investigate if children (7–17 years) with frequent episodic tension-type headache (FETTH) or chronic TTH (CTTH) have an altered pain perception compared to healthy controls. Methods We applied a pressure of five increasing intensities to m. trapezius and m. temporalis with a Somedic Algometer II. Visual analogue scale-score was rated and area under the curve (AUC) calculated. An average AUC in each person was used as an outcome variable in further univariate multiple linear regression analysis because factor analysis showed that AUC represents only one dimension underlying both muscles. Results Participants included 22 children with FETTH, 36 children with CTTH and 57 controls. The CTTH group had a significantly higher AUC compared to the control group ( p < 0.001). The FETTH group represented an intermediate state. AUC did not change with increasing age, headache years, headache intensity, headache frequency or sex. Conclusion Children with CTTH show significantly increased pain sensitivity in a range of pressures compared to the FETTH group and the controls. Since AUC in m. trapezius and m. temporalis represents only one general latent tenderness, it might indicate that the altered pain perception is mainly due to central sensitisation.
Functional and effective connectivity in EEG alpha and beta bands during intermittent flash stimulation in migraine with and without aura
Authors: de Tommaso Marina , Stramaglia Sebastiano , Marinazzo Daniele , Trotta Gabriele , Pellicoro Mario 
Published: February 2013

Objectives: This research was a case-control study to evaluate functional and effective connectivity patterns in ongoing electroencephalography (EEG) under repetitive photic stimulation in the interictal phase of migraine patients with and without aura compared to nonmigraine controls. Methods: EEG was recorded by six scalp electrodes from 19 migraine without aura patients (MO), 19 migraine with aura patients (MA) and 11 healthy subjects (control group (N)). Flash stimuli were presented at 9–27 Hz frequencies. Phase synchronization after Hilbert transform and Granger causality were evaluated filtering the EEG in alpha and beta bands. Results: Phase synchronization increased in alpha band in MO, and decreased in beta band in MA, with respect to controls. The intensity of directed interactions in beta band, revealed by Granger causality, increased in MA compared to both MO patients and controls. Discussion: There were clear differences in ongoing EEG under visual stimulation, which emerged between the two forms of migraine, probably subtended by increased cortical activation in migraine with aura, and compensatory phenomena of reduced connectivity and functional networks segregation, occurring in patients not experiencing aura symptoms. Further investigation may confirm whether the clinical manifestation of aura symptoms is subtended by a peculiar neuronal connectivity pattern.
Dream-enacting behaviour is associated with impaired sleep and severe headache-related disability in migraine patients
Authors: Suzuki Keisuke , Miyamoto Tomoyuki , Miyamoto Masayuki , Suzuki Shiho , Watanabe Yuka , Takashima Ryotaro , Hirata Koichi 
Published: February 2013

Background Sleep disorders, nightmares and visual hallucinations have been reported in migraine patients, which may suggest the involvement of rapid eye movement (REM) sleep regulation in migraine. However, the relationship between migraine and REM sleep behaviour disorder (RBD) remains unclear. Methods To investigate the clinical correlates of dream-enacting behaviours (DEB) in migraine patients, we assessed episodic migraine patients ( n = 161, mean age 33.1 years) and headache-free control subjects ( n = 140, mean age 33.1 years) under 50 years of age in a cross-sectional, case-control study. The Japanese version of the RBD screening questionnaire was used, and subjects scoring 5 or higher were defined as having DEB. Results A significantly increased frequency of DEB was observed in migraine patients compared to controls (24.2% vs. 14.3%). Migraine patients with DEB presented higher scores on the Migraine Disability Assessment and Pittsburgh Sleep Quality Index and an increased rate of smoking compared to those without DEB. Duration of migraine and headache frequency and intensity were not different between migraine patients with or without DEB. Conclusion DEB was associated with impaired sleep and severe headache-related disability in migraine patients and may reflect brainstem dysfunction and increased brain excitability in migraine patients.
Effects of kenaf loading and 3-aminopropyltriethoxysilane coupling agent on the properties of polypropylene/waste tire dust/kenaf composites
Authors: Pang Ailing , Ismail Hanafi 
Published: February 2013

The effects of kenaf (KNF) loading and 3-aminopropyltriethoxysilane (APTES) on processing torque, tensile properties and morphological properties of KNF-filled polypropylene (PP)/waste tire dust (WTD) composites were investigated. In this research, PP/WTD served as a matrix and KNF as a filler and the composites were prepared using a Thermo Haake Polydrive internal mixer, where different KNF loadings (0, 5, 10, 15 and 20 parts per hundred parts of resin) were used. The results revealed that the stabilization torque and tensile modulus increased with increasing KNF loading but tensile strength and elongation at break were found to decrease. The composites with APTES exhibited higher stabilization torque, tensile strength and tensile modulus but lower elongation at break than composites without APTES. The presence of APTES had enhanced the interfacial adhesion between PP/WTD matrix and KNF, which had resulted in higher tensile strength and modulus of the composites. These findings were supported by the morphological study on the tensile fractured surfaces of the composites.
Psychiatric symptoms associated with the mental health defence for serious violent offences in Queensland
Authors: Spencer Jillian , Tie Anthony 
Published: February 2013

Objective: The purpose of this study was to examine which psychiatric symptoms were associated with a defence of unsoundness of mind for serious violent offences. Method: The study included psychiatric reports provided by forensic psychiatrists from the High Secure Inpatient Service for patients found to have a mental health defence by the Mental Health Court between June 2004 and June 2009. Results: The defence of unsoundness of mind was invariably associated with psychotic symptoms. All reports concluded that the patient was deprived of knowledge of the wrongfulness of the act. Patients found to be additionally deprived of the capacity to understand their actions suffered delusional beliefs about the identity of the victim. The symptoms that resulted in a small number of patients being considered deprived of the capacity to control their actions were mixed, but approximately a third suffered passivity phenomena. Conclusions: Psychiatrists should be specific about how the patient’s symptoms link to any deprivation of capacity. Report writers could comment upon the presence or absence of Axis II conditions and the likely impact of any substances in the patient’s system at the time of the offence.
Echocardiographic monitoring for clozapine cardiac toxicity: lessons from real-world experience
Authors: Murch Stuart , Tran Nga , Liew Danny , Petrakis Melissa , Prior David , Castle David 
Published: February 2013

Objective: We aimed to identify the baseline prevalence of cardiac dysfunction in patients commencing clozapine, assess adherence with echocardiographic monitoring recommendations, and evaluate the utility and cost of echocardiographic monitoring for the development of clozapine-associated myocarditis and cardiomyopathy. Methods: A retrospective longitudinal cohort study was undertaken of 159 consecutive patients from a major tertiary centre commencing clozapine in the period January 2002 to July 2009. Results: Some 73% of patients had a baseline study, and 11% had a six-month follow-up study. Nine patients had abnormal left ventricular function at baseline. Myocarditis was identified in three patients, with all cases occurring within the first month of treatment and suspected on clinical grounds before an echocardiogram was performed. One case of possible cardiomyopathy was identified. The cost of echocardiographic screening in the first year of treatment was estimated at $AUD 209,356 per case of cardiomyopathy detected. Conclusion: The prevalence of cardiac dysfunction in patients commencing clozapine is high, and there are challenges in adhering with the recommended protocol for monitoring. Routine echocardiography is not useful in the detection of clozapine-associated myocarditis. Although cardiomyopathy may be identified, it is rare and associated with significant cost. Recommendations for routine echocardiographic monitoring should be re-examined.
The Mood Assessment Program is now on the Australian map
Authors: Parker Gordon , Anonuevo Cesar , Wallace Jacqui , Fletcher Kathryn , Paterson Amelia 
Published: February 2013

Objective: To report on the wide uptake and utility of the freely available Mood Assessment Program (MAP) since its introduction as a tool to assist diagnosis and management of mood disorders. Method: By mid-2012, some 16,000 patients had completed the MAP. We analyse data derived from such a sample. Results: The majority of patients utilizing this service were referred by general practitioners, psychologists and psychiatrists from within New South Wales (NSW). The great majority across age bands found the MAP easy to complete and judged that it covers issues relating to their mood disorder very well or completely. Conclusion: The MAP is available for use Australia-wide with ready referral access for patients of mental health practitioners in general practice, psychiatry, psychology and social work. The online availability of the service makes it ideal for use in areas where access to health services is limited.
Gustav Mahler as Freud’s patient: a note on possible obstacles to communication and understanding
Authors: Starcevic Vladan 
Published: February 2013

Objective: This article examines the meeting between Gustav Mahler and Sigmund Freud from a perspective that takes into account possible obstacles to their interaction. Conclusions: Mahler consulted Freud in the context of a marital crisis in 1910. While it appears that a meeting between the two men had some positive effects on Mahler, its long-term impact will never be known because Mahler died only eight months later. This consultation is first examined in the light of a number of its implications and questions for contemporary psychotherapy. The fact that Freud was unable to appreciate music did not seem to interfere with a very focused, ultra-brief intervention for the patient completely devoted to music. On the other hand, Mahler’s series of death-related traumas, a life-long preoccupation with death and fear of death, were apparently unnoticed by Freud, who neglected fear of death as an important intrapsychic force and provided an explanation to Mahler that was in accordance with his theories. The article concludes with a comment on the speculation about the link between creativity on one hand and unsatisfied libido and psychological conflicts on the other.
Natalizumab treatment decreases serum IgM and IgG levels in multiple sclerosis patients
Authors: Selter Rebecca C , Biberacher Viola , Grummel Verena , Buck Dorothea , Eienbröker Christian , Oertel Wolfgang H , Berthele Achim , Tackenberg Björn , Hemmer Bernhard 
Published: February 2013

Background: Treatment with natalizumab, a humanized monoclonal antibody against alpha4beta1 integrin, is associated with an increase in lymphoid progenitor cells and B cells in peripheral blood. Objective: The objective of this study was to examine the impact of natalizumab therapy on serum levels of total IgG, IgA and IgM in patients with multiple sclerosis (MS). Methods: In two independent cross-sectional patient cohorts, serum levels of IgG, IgA and IgM were compared between patients treated with natalizumab and those not receiving natalizumab. Further, serum levels of IgG, IgA and IgM before and during natalizumab treatment were compared in two longitudinal patient cohorts. Results: In patients treated with natalizumab, serum IgM and IgG levels were significantly lower compared with therapy naïve patients ( p<0.0001). IgM levels significantly decreased after initiation of natalizumab treatment in both longitudinal patient cohorts ( p<0.01). Moreover, patients treated with natalizumab showed a time-dependent decrease in IgM levels during the first 2 years of treatment. Conclusion: Natalizumab treatment leads to a significant decrease in serum IgM and IgG levels in patients with MS. IgM levels decrease with treatment duration during the first 2 years of treatment. These findings might support the hypothesis that natalizumab interferes with homing of B cells, possibly leading to impaired differentiation into plasma cells and subsequently disturbed immunoglobulin synthesis.
Learning and cognitive fatigue trajectories in multiple sclerosis defined using a burst measurement design
Authors: Holtzer Roee , Foley Frederick , D’Orio Vanessa , Spat Jessica , Shuman Melissa , Wang Cuiling 
Published: February 2013

Background: Compromised learning and cognitive fatigue are critical clinical features in multiple sclerosis. Objectives: This study was designed to determine the effect of repeated exposures within and across study visits on performance measures of learning and cognitive fatigue in relapsing–remitting multiple sclerosis (RRMS). Methods: Thirty patients with RRMS and 30 controls were recruited. Using a burst measurement design (i.e. repeated assessments within and across study visits) the oral version of the Symbol Digit Modalities Test (SDMT) was administered three times during the baseline and two consecutive monthly follow-up visits for a total of nine test administrations. Learning was assessed within and across study visits whereas cognitive fatigue was assessed during the course of each test administration that was divided into three 30-second intervals. Results: Linear mixed-effect models revealed compromised learning within (95% CI: 2.6355 to 3.9867) and across (95% CI: 1.3250 to 3.1861) visits and worse cognitive fatigue (95% CI: −2.1761 to −0.1720) in patients with RRMS compared with controls. Among patients with RRMS, worse self-rated cognitive dysfunction predicted poor learning within (95% CI: −0.1112 to −0.0020) and across (95% CI: −0.0724 to −0.0106) visits. Conclusions: Burst design is optimal to study learning and cognitive fatigue. This methodology, using the SDMT or other time-efficient tests as outcome measures, can be successfully implemented in longitudinal studies and clinical trials.
A diabetic patient treated for hypertension develops tremors and twitches
Authors: Gandhi Nirav Y , Shakher Jayadave 
Published: February 2013

Objective: To report an unusual but known cause of hypomagnesaemia-induced hypocalcaemia and review the relevant literature. Methods: We present the clinical and laboratory findings in a case of hypomagnesaemia induced-hypocalcaemia, and discuss the underlying mechanisms in light of the available literature. Results: After admission our patient described typical features of magnesium deficiency such as weakness, tremors and muscle twitches. He also had clinical signs of hypocalcaemia such as a pronounced carpal pedal spasm. Blood results revealed that he had low calcium and magnesium. This was further confirmed by another set of blood results. His vitamin D levels were normal at 25.2 pg/mL and 27.3 pg/mL. His parathyroid hormone was at 18.5 pg/mL (12–72). His urea and electrolytes were normal with sodium of 137 mmol/l, potassium of 3.8 mmol/l, creatinine of 93 mL/minute, and liver function tests in the normal range. Hypomagnesaemia is a common finding and has been reported to be present in nearly 12% of hospitalised patients. From a review of published reports, it is seen that most cases of hypomagnesaemia are due to gastrointestinal or renal losses, but it is also seen with excess alcohol consumption. Drugs such as proton pump inhibitors and, although not often reported, thiazide diuretics are known to cause hypomagnesaemia. The patient was on Indapamide for his hypertension. With replacement therapy, both his ion levels returned back to normal. Conclusion: Hypomagnesaemia is often usually associated with multiple biochemical abnormalities. The increasing use of diuretics and the introduction of potent preparations present a considerable risk for hypomagnesaemia induced-hypocalcaemia.
BAUS Section of Endourology national Ureteroscopy audit: setting the standards for revalidation
Authors: Mangera A , Parys B 
Published: February 2013

Objective: Ureteroscopic stone treatment is one of endourology’s ‘signature’ procedures. With a view to forthcoming revalidation demands and improving outcomes, there was a need for the British Association of Urological Surgeons (BAUS) Section of Endourology and its individual members to know how commonly, competently and successfully this procedure is performed. Methods: All surgeons belonging to the BAUS Section of Endourology undertaking ureteroscopy (URS) for stone treatment in the United Kingdom were invited to take part in a two-week prospective audit with the instructions to input all URS performed for stone disease in that period on a standardised proforma. Results: In total, 143 procedures were reported over two weeks. Peri-operative practices varied in the use of on the day pre-operative imaging, stent usage and treatment modality. Overall stone free rates for all URS was 78% with a complications rate of 4%. Conclusion: This is the first study of its kind to have highlighted the demographics of patients undergoing URS in the UK and provides surgeons with information on practices around the country. It also provides realistic outcomes from real-life practice which, if taken forward to a registry, may be incorporated into revalidation.