bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Irreversible endo‐Selective Diels—Alder Reactions of Substituted Alkoxyfurans: A General Synthesis of endo‐Cantharimides.
Authors: Foster Robert W. , Benhamou Laure , Porter Michael J. , Bucar Dejan‐Kresimir , Hailes Helen C. , Tame Christopher J. , Sheppard Tom D. 
Published: August 2015

AbstractCycloaddition of 3‐alkoxyfurans with N‐substituted maleimides provides the first general route towards endo‐cantharimide analogs.
ChemInform Abstract: Cu‐Nanoparticles on Cellulose/H2O—CH3CN/Microwave: A Green System for the Selective Oxidation of Alcohols to Aldehydes.
Authors: Baruah Diganta , Saikia Ujwal Pratim , Pahari Pallab , Konwar Dilip 
Published: August 2015

AbstractAn inexpensive and environment friendly green reusable heterogeneous catalytic system copper nanoparticles on cellulose template/H2O—CH3CN/microwave which oxidizes benzylic alcohols, cinnamyl alcohols, and heteroarylalcohols to the corresponding aldehydes in very short reaction time is reported.
ChemInform Abstract: Titanium‐Catalyzed Reductive Umpolung Reactions with a Metal‐Free Terminal Reducing Agent.
Authors: Frey Georg , Hausmann J. Niklas , Streuff Jan 
Published: August 2015

AbstractA new method for Ti‐catalyzed reductive umpolung reactions is reported that overcomes the traditional requirement for a stoichiometric metallic reductant.
ChemInform Abstract: Cobalt‐Catalyzed C—H Arylations with Weakly‐Coordinating Amides and Tetrazoles: Expedient Route to Angiotensin‐II‐Receptor Blockers.
Authors: Li Jie , Ackermann Lutz 
Published: August 2015

AbstractThe use of weakly‐coordinating benzamides, e.g. (I), (IV), (VI), and (VIII), for C—H arylations is reported.
ChemInform Abstract: Selective Synthesis of Nitroalcohols in the Presence of Ambersep 900 OH as Heterogeneous Catalyst.
Authors: Lodh Rajsekhar , Sarma Manas Jyoti , Borah Arun Jyoti , Phukan Prodeep 
Published: August 2015

AbstractNitroalcohols are prepared by Henry reaction of aldehydes with nitromethane using Ambersep 900 OH anionic ion‐exchanger resin as catalyst.
ChemInform Abstract: A Zinc Enolate of Amide: Preparation and Application in Reformatsky‐Like Reaction Leading to β‐Hydroxy Amides.
Authors: Cho Hyun‐Hee , Kim Seung‐Hoi 
Published: August 2015

AbstractAn efficient new synthetic route for the preparation of β‐hydroxy amides is presented starting from room‐temperature‐stable organozinc reagents by coupling reactions with various carbonyl derivatives under mild conditions.
ChemInform Abstract: Synthesis of Substituted Carbamo(dithioperoxo)thioates as Potential BCA2‐Inhibitory Anticancer Agents.
Authors: Cilibrasi Vincenzo , Tsang Kwok , Morelli Matteo , Solfa Francesca , Wiggins Helen L. , Jones Arwyn T. , Westwell Andrew D. 
Published: August 2015

AbstractA new one‐pot synthetic route to a range of potential anticancer carbamo(dithioperoxo)thioates in high yields from commercially available starting materials is described.
ChemInform Abstract: (E)‐Specific Direct Julia‐Olefination of Aryl Alcohols Without Extra Reducing Agents Promoted by Bases.
Authors: Yao Chuan‐Zhi , Li Qiang‐Qiang , Wang Mei‐Mei , Ning Xiao‐Shan , Kang Yan‐Biao 
Published: August 2015

AbstractA base‐promoted direct olefination of aryl alcohols with sulfones via a Julia‐type reaction is established.
ChemInform Abstract: Re2O7 Catalyzed Dienone‐Phenol Rearrangement.
Authors: Xia Zilei , Hu Jiadong , Shen Zhigao , Yao Qizheng , Xie Weiqing 
Published: August 2015

AbstractMultisubstituted phenols are efficiently obtained by dienone‐phenol rearrangement of 4,4‐disubstituted cyclohexadienones.
ChemInform Abstract: Bulky Guanidinate Stabilized Homoleptic Magnesium, Calcium and Zinc Complexes and Their Catalytic Activity in the Tishchenko Reaction.
Authors: Barman Milan Kr , Baishya Ashim , Nembenna Sharanappa 
Published: August 2015

AbstractIt is demonstrated that the Mg complex MGG efficiently catalyzes the dimerization of aromatic aldehydes.
ChemInform Abstract: A Novel and Efficient Zinc‐Catalyzed Thioetherification of Aryl Halides.
Authors: Thankachan Amrutha P. , Sindhu K. S. , Krishnan K. Keerthi , Anilkumar Gopinathan 
Published: August 2015

AbstractA variety of aryl and alkyl sulfides are obtained via C—S cross‐coupling reaction of aryl halides with both aryl and alkyl thiols using ZnEt2/L‐proline as easily available, cheap, and environmentally benign catalytic system.
ChemInform Abstract: Unprecedented Formation of Spiro[indoline‐3,7′‐pyrrolo[1,2‐a]azepine] from Multicomponent Reaction of L‐Proline, Isatin and But‐2‐ynedioate.
Authors: Yang Fan , Sun Jing , Gao Hong , Yan Chao‐Guo 
Published: August 2015

AbstractSpiro[indoline‐3,3′‐pyrrolizines] (IV), (VI) and (VIII) are obtained by normal 1,3‐cycloaddition reaction of α‐amino acids, isatins, and but‐2‐ynedioates.
ChemInform Abstract: A Novel and One‐Pot Method for Synthesis of Unprecedented 3,3‐Dimethyl‐2‐amide Indoles under Metal‐Free Conditions.
Authors: Liu Haidong , Chen Hao , Li Yuan , Lv Yongfeng , Cai Jin , Ji Min 
Published: August 2015

AbstractTitle compounds (III) are prepared via a novel oxidative amination reaction between indolium salts (I) and cyclic secondary amines (II).
ChemInform Abstract: Synthesis of 1,2,4,5‐Tetrasubstituted Imidazoles Using 2,6‐Dimethylpyridinium Trinitromethanide {[2,6‐DMPyH]C(NO2)3} as a Novel Nanostructured Molten Salt and Green Catalyst.
Authors: Zolfigol Mohammad Ali , Baghery Saeed , Moosavi‐Zare Ahmad Reza , Vahdat Seyed Mohammad 
Published: August 2015

AbstractImidazoles (IV) are obtained by one‐pot four‐component condensation reaction of benzil (I) or benzoin, various aromatic aldehydes (II), amines (III), and ammonium acetate under solvent‐free conditions using the novel, eco‐friendly nanostructured molten salt (PNM) as catalyst.
ChemInform Abstract: Graphene Oxide—Chitosan Bionanocomposite: A Highly Efficient Nanocatalyst for the One‐Pot Three‐Component Synthesis of Trisubstituted Imidazoles under Solvent‐Free Conditions.
Authors: Maleki Ali , Paydar Reza 
Published: August 2015

AbstractImidazoles (III) are rapidly, conveniently, and eco‐friendly obtained by reaction of benzil (I) or benzoin with various aromatic aldehydes and ammonium acetate.
ChemInform Abstract: Synthesis of Some Novel Bisisoxazolidine Derivatives from Glyoxal‐Derived Bisnitrones via Simultaneous Double Cycloaddition Reactions in Water.
Authors: Chakraborty Bhaskar , Luitel Govinda Prasad 
Published: August 2015

AbstractA new methodology for the synthesis of bisisoxazolidines from one‐pot double cycloaddition reactions of bifunctional nitrones (I) with maleimides and other activated alkenes is given.
ChemInform Abstract: Enantioselective Copper‐Catalyzed Alkynylation of Benzopyranyl Oxocarbenium Ions.
Authors: Srinivas Harathi D. , Maity Prantik , Yap Glenn P. A. , Watson Mary P. 
Published: August 2015

AbstractIsochromanes (I) and (IV) and chromene acetals (VII) and (IX) are alkynylated in good to high yields and with high enantioselectivities using Bn‐Box ligands.
ChemInform Abstract: 3‐(1‐Phenyl‐4‐((2‐ (4‐arylthiazol‐2‐yl)hydrazono)methyl)‐1H‐pyrazol‐3‐yl) ‐2H‐chromen‐2‐ones: One‐Pot Three Component Condensation, in vitro Antimicrobial, Antioxidant and Molecular Docking Studies.
Authors: Gondru Ramesh , Banothu Janardhan , Thatipamula Ranjith Kumar , Hussain SK Althaf , Bavantula Rajitha 
Published: August 2015

AbstractCompounds (IVa), (IVh) and (IVi) are found to show a broad spectrum antibacterial activity, whereas compounds (IVb) and (IVf) are potent antifungal agents.
ChemInform Abstract: Stereocontrolled Synthesis of Vicinally Functionalized Piperidines by Nucleophilic β‐Addition of Alkyllithiums to α‐Aryl Substituted Piperidine Enecarbamates.
Authors: Beng Timothy K. , Takeuchi Hironori , Weber Manuel , Sarpong Richmond 
Published: August 2015

AbstractThe first examples of highly diastereoselective carbolithiations of α‐arylated dehydro‐piperidine enecarbamates with alkyllithium nucleophiles is described.
ChemInform Abstract: CBr4‐Mediated Cross‐Dehydrogenative Coupling Reaction of Amines.
Authors: Huo Congde , Xie Haisheng , Wu Mingxia , Jia Xiaodong , Wang Xicun , Chen Fengjuan , Tang Jing 
Published: August 2015

AbstractA novel CBr4‐mediated dehydrogenative Povarov/aromatization tandem reaction of glycine derivatives (I) and (IV) with alkenes (II) and (V), leading to complex quinoline derivatives (III) and (V) is reported.
ChemInform Abstract: Ga(OTf)3‐Promoted Synthesis of Functionalized 2‐Carbonyl‐imidazo[1,2‐a]pyridines Derived from Ethyl α‐Benzotriazolyl‐α‐morpholinoacetate.
Authors: Yang Fengxia , An Weiteng , Qian Zhiwei , Yu Ting , Du Yongli , Ma Lanping , Wang Xin , Meng Tao , Shen Jingkang 
Published: August 2015

AbstractThe title imidazo[1,2‐a]pyridines (V), (VIII), (XI) are obtained by Ga(OTf)3‐ catalyzed reaction of various primary heterocyclic amidines and isocyanides.
ChemInform Abstract: A Convenient Synthesis and Biological Activity of Novel Pyrido[4,3‐d]pyrimidin‐4(3H)‐ones.
Authors: Ren Qingyun , Xia ShiYan , Gu Yucheng , Li Baoju , He Hongwu 
Published: August 2015

AbstractSome novel pyrimidin‐4‐one derivatives (V) are successfully formed via a tandem aza‐Wittig annulation reaction of corresponding imino‐phosphorane (I), aryl isocyanates and amines.
ChemInform Abstract: A FRET—ICT Dual‐Quenching Fluorescent Probe with Large Off—On Response for H2S: Synthesis, Spectra and Bioimaging.
Authors: Zhang Changyu , Wei Lv , Wei Chao , Zhang Jie , Wang Runyu , Xi Zhen , Yi Long 
Published: August 2015

AbstractCompound (I) is a sensitive and selective fluorescent probe for H2S in a buffer and in living cells.
ChemInform Abstract: [4 + 2] Heterocyclization for Efficient Formation of Substituted Quinoxalines Through Carbon—Oxygen Bonds Cleavage.
Authors: Tu Man‐Su , Xu Hai‐Wei , Fan Wei , Jiang Bo , Tu Shu‐Jiang 
Published: August 2015

AbstractA new domino strategy for an efficient synthesis of highly functionalized quinoxaline derivatives (III) is developed using a [4 + 2] heterocyclization procedure involving a ring‐opening of oxirane.
ChemInform Abstract: Microwave‐Assisted Expedite Synthesis of 2‐Phenylimidazo[1,2‐a]pyridylquinoxalin‐2(1H)‐ones.
Authors: Sakhuja Rajeev , Shakoor S. M. Abdul , Kumari Santosh , Kumar Anil 
Published: August 2015

AbstractAn efficient method for the synthesis of the title compounds (V) is developed using a microwave‐assisted Hinsberg heterocyclization using either montmorillonite or Yb(OTf)3 as catalysts.
ChemInform Abstract: Synthesis of [1,2,4]Triazolo[4′′,3′′:1′,6′]pyrimido[4′,5′:3,4]pyridazino[1,6‐d] [1,2,4]triazine; a Novel Tetracyclic System.
Authors: Hazrathoseyni Ayla , Seyedi Seyed Mohammad , Shiri Ali , Eshghi Hossein 
Published: August 2015

AbstractThe synthesis of the first representatives of the novel tetracyclic heterocyclic system (VII) are synthesized via two consecutive cyclocondensation reactions.
ChemInform Abstract: Iron‐Catalyzed C—H Borylation of Arenes.
Authors: Dombray Thomas , Werncke C. Gunnar , Jiang Shi , Grellier Mary , Vendier Laure , Bontemps Sebastien , Sortais Jean‐Baptiste , Sabo‐Etienne Sylviane , Darcel Christophe 
Published: August 2015

AbstractBoth aromatic and heteroaromatic arenes undergo dehydrogenative borylation with pinacolborane catalyzed by a well‐defined iron bis(diphosphine) complexes under UV irradiation.
ChemInform Abstract: C—H Bonds Phosphorylation of Ketene Dithioacetals.
Authors: Zhu Liping , Yu Hongmei , Guo Quanping , Chen Qiao , Xu Zhaoqing , Wang Rui 
Published: August 2015

AbstractThe title reaction is mediated by K2S2O8 or AgNO3 and the products can be further transformed to tetrasubstituted alkene and N‐heterocycles.
ChemInform Abstract: Design and Synthesis of 2′‐Deoxy‐2′‐[(1,2,3)triazol‐1‐yl]uridines Using Click Chemistry Approach.
Authors: Kumar Surender 
Published: August 2015

AbstractTitle compounds (III) are synthesized starting from 2′‐azidouridine (I) using the copper (I)‐catalyzed Huisgen—Sharpless—Meldal 1,3‐dipolar cycloaddition reaction.
ChemInform Abstract: Cu(I)‐Catalyzed Efficient Synthesis of 2′‐Triazolo‐nucleoside Conjugates.
Authors: Mathur D. , Rana N. , Olsen C. E. , Parmar V. S. , Prasad A. K. 
Published: August 2015

AbstractA library of novel triazolyl conjugates of uridine and 5‐methyluridine (III) (22 examples) is efficiently and conveniently synthesized by a Cu(I)‐catalyzed 1,3‐dipolar cycloaddition reaction.
ChemInform Abstract: Nonfunctionalized Gold Nanoparticles: Synthetic Routes and Synthesis Condition Dependence
Authors: Jimenez‐Ruiz Aila , Perez‐Tejeda Pilar , Grueso Elia , Castillo Paula M. , Prado‐Gotor Rafael 
Published: August 2015

AbstractReview: some of the most relevant synthetic procedures reported up to date, with a special focus on synthetic routes to nonfunctionalized gold nanoparticle in aqueous media, influence of synthesis conditions on the shape, stability, and reactivity of the nanoparticles; 92 refs.
ChemInform Abstract: Conjugated Radical Cation Dimerization‐Driven Generation of Supramolecular Architectures
Authors: Chen Lan , Zhang Yun‐Chang , Wang Wei‐Kun , Tian Jia , Zhang Liang , Wang Hui , Zhang Dan‐Wei , Li Zhan‐Ting 
Published: August 2015

AbstractReview: [32 refs.
ChemInform Abstract: Acetaldehyde in Asymmetric Organocatalytic Transformations
Authors: Kumar Manjeet , Kumar Arvind , Rizvi Masood Ahmad , Shah Bhahwal Ali 
Published: August 2015

AbstractReview: [recent developments in the use of acetaldehyde as substrate in various organo‐catalyzed organic transformations and its application in the synthesis of bioactive molecules; 67 refs.
Highly Efficient Synthesis of Arylpyrrole Derivatives via Rh(III)‐Catalyzed Direct CH Arylation with Aryl Boronic Acids
Authors: Wang Liang , Li Zhan , Qu Xing , Peng Wangming 
Published: August 2015

AbstractAn efficient and facile method for synthesis of 2‐arylpyrroles through Rh(III)‐catalyzed direct CH arylation with pyrrole derivatives and aryl boronic acids has been developed. This reaction could proceed under mild reaction conditions and afford a series of 2‐arylated products in good to excellent yields. The gram‐scale experiment has been conducted to demonstrate the synthetic potential of this methodology.
Direct Three‐Component Synthesis of α‐Cyano Acrylates Involving Cascade Knoevenagel Reaction and Esterification
Authors: Jing Yanfeng , Meng Jiaojiao , Liu Yunyun , Wan Jie‐Ping 
Published: August 2015

AbstractA direct three‐component approach has been developed for the synthesis of α‐cyano acrylates starting from aldehydes, alcohols and α‐cyano acetamide by employing cyanuric chloride as an organocatalyst. A class of structurally diverse α‐cyano acrylates have been provided with good to excellent yields via the cascade transformation of Knoevenagel condensation and amide esterification.
Lipopeptide Nanoparticles: Development of Vaccines against Hookworm Parasite
Authors: Fuaad Abdullah A. H. Ahmad , Pearson Mark S. , Pickering Darren A. , Becker Luke , Zhao Guangzu , Loukas Alex C. , Skwarczynski Mariusz , Toth Istvan 
Published: August 2015

AbstractNecator americanus (hookworm) infects over half a billion people worldwide. Anthelminthic drugs are commonly used to treat the infection; however, vaccination is a more favorable strategy to combat this parasite. We designed new B‐cell peptide epitopes based on the aspartic protease of N. americanus (Na‐APR‐1). The peptides were conjugated to self‐adjuvanting lipid core peptide (LCP) systems via stepwise solid‐phase peptide synthesis (SPPS) and copper catalyst azide–alkyne cycloaddition (CuAAC) reactions. The LCP vaccine candidates were able to self‐assemble into nanoparticles, were administered to mice without the use of additional adjuvant, and generated antibodies that recognized the parent epitope. However, only one LCP derivative was able to produce a high titer of antibodies specific to Na‐APR‐1; circular dichroism analyses of this compound showed a β‐sheet conformation for the incorporated epitope. This study provides important insight in epitope and delivery system design for the development of a vaccine against hookworm infections.
Universal radio‐frequency receive‐coil connector: Concept and validation at 3 T
Authors: Feuillet Thomas , Saint‐Jalmes Herve , Seurin Marie‐Jose , Bordelois Alejandro , Beuf Olivier 
Published: August 2015

ABSTRACTIn most clinical magnetic resonance imaging systems, only commercial receive coils with the appropriate connector and encoding can be plugged in. When willing to use a dedicated receive coil for a specific study which cannot be achieved with commercial coils, the researcher faces the connecting issue related to the specificity of the proprietary connector. In this work, a universal device is proposed which allows for the connection of any single channel dedicated coil on any magnetic resonance (MR) system, as long as it is provided with at least one commercial receive coil. Technical feasibility of the universal connecting device was demonstrated on a 3 T MR clinical imager. The device included an independent active decoupling circuit while signal transmission to the data cabinet was achieved by electromagnetic coupling with a commercial receive coil plugged to the MR device. The universal connecting device was notably characterized in terms of signal‐to‐noise ratio (SNR) and compared to the standard connection. Image SNR was comparable using both means of connection. © 2015 Wiley Periodicals, Inc. Concepts Magn Reson Part B (Magn Reson Engineering) 45B: 125–133, 2015
Ga+Basicity and Affinity Scales Based on High‐Level Ab Initio Calculations
Authors: Brea Oriana , Mó Otilia , Yáñez Manuel 
Published: August 2015

AbstractThe structure, relative stability and bonding of complexes formed by the interaction between Ga+and a large set of compounds, including hydrocarbons, aromatic systems, and oxygen‐, nitrogen‐, fluorine and sulfur‐containing Lewis bases have been investigated through the use of the high‐level composite ab initio Gaussian‐4 theory. This allowed us to establish rather accurate Ga+cation affinity (GaCA) and Ga+cation basicity (GaCB) scales. The bonding analysis of the complexes under scrutiny shows that, even though one of the main ingredients of the Ga+‐base interaction is electrostatic, it exhibits a non‐negligible covalent character triggered by the presence of the low‐lying empty 4p orbital of Ga+, which favors a charge donation from occupied orbitals of the base to the metal ion. This partial covalent character, also observed in AlCA scales, is behind the dissimilarities observed when GaCA are compared with Li+cation affinities, where these covalent contributions are practically nonexistent. Quite unexpectedly, there are some dissimilarities between several Ga+‐complexes and the corresponding Al+‐analogues, mainly affecting the relative stability of π‐complexes involving aromatic compounds.
BAC transgenic zebrafish reveal hypothalamic enhancer activity around obesity associated SNP rs9939609 within the human FTO gene
Authors: Rinkwitz Silke , Geng Fan‐Suo , Manning Elizabeth , Suster Maximiliano , Kawakami Koichi , Becker Thomas S. 
Published: August 2015

SummarySingle Nucleotide Polymorphisms in FTO intron 1 have been associated with obesity risk, leading to the hypothesis that FTO is the obesity‐related gene. However, other studies have shown that the FTO gene is part of the regulatory domain of the neighboring IRX3 gene and that enhancers in FTO intron 1 regulate IRX3. While Irx3 activity was shown to be necessary in the hypothalamus for the metabolic function of Irx3 in mouse, no enhancers with hypothalamic activity have been demonstrated in the risk‐associated region within FTO. In order to identify potential enhancers at the human FTO locus in vivo, we tested regulatory activity in FTO intron 1 using BAC transgenesis in zebrafish. A minimal gata2 promoter‐GFP cassette was inserted 1.3 kb upstream of the obesity associated SNP rs9939609 in a human FTO BAC plasmid. In addition to the previously identified expression domains in notochord and kidney, human FTO BAC:GFP transgenic zebrafish larvae expressed GFP in the ventral posterior tuberculum, the posterior hypothalamus and the anterior brainstem, which are also expression domains of zebrafish irx3a. In contrast, an in‐frame insertion of a GFP cassette at the FTO start codon resulted in weak ubiquitous GFP expression indicating that the promoter of FTO does likely not react to enhancers located in the obesity risk‐associated region. genesis 53:640–651, 2015. © 2015 The Authors. genesis Published by Wiley Periodicals, Inc.
Insect responses to host plant provision beyond natural boundaries: latitudinal and altitudinal variation in a Chinese fig wasp community
Authors: Wang Rong , Compton Stephen G. , Quinnell Rupert J. , Peng Yan‐Qiong , Barwell Louise , Chen Yan 
Published: August 2015

AbstractMany plants are grown outside their natural ranges. Plantings adjacent to native ranges provide an opportunity to monitor community assembly among associated insects and their parasitoids in novel environments, to determine whether gradients in species richness emerge and to examine their consequences for host plant reproductive success. We recorded the fig wasps (Chalcidoidea) associated with a single plant resource (ovules of Ficus microcarpa) along a 1200 km transect in southwest China that extended for 1000 km beyond the tree's natural northern range margin. The fig wasps included the tree's agaonid pollinator and other species that feed on the ovules or are their parasitoids. Phytophagous fig wasps (12 species) were more numerous than parasitoids (nine species). The proportion of figs occupied by fig wasps declined with increasing latitude, as did the proportion of utilized ovules in occupied figs. Species richness, diversity, and abundance of fig wasps also significantly changed along both latitudinal and altitudinal gradients. Parasitoids declined more steeply with latitude than phytophages. Seed production declined beyond the natural northern range margin, and at high elevation, because pollinator fig wasps became rare or absent. This suggests that pollinator climatic tolerances helped limit the tree's natural distribution, although competition with another species may have excluded pollinators at the highest altitude site. Isolation by distance may prevent colonization of northern sites by some fig wasps and act in combination with direct and host‐mediated climatic effects to generate gradients in community composition, with parasitoids inherently more sensitive because of declines in the abundance of potential hosts.
Effect of freeze–thaw cycles on the nutritional quality of some selected Nigerian soups
Authors: Raji Akeem Olayemi , Akinoso Rahman , Raji Monsurat Oyewale 
Published: August 2015

AbstractFreezing and thawing are heat transfer processes, involving chemical changes which may greatly affect product quality. Due to sparse literature on freeze–thawed cycles and its effects on soups quality, the effect of freeze–thaw cycles on the nutritional quality of selected Nigerian soups has to be investigated. Soups (Ila, Ewedu, Ogbono, and Kuka) were prepared using standard recipes. The soups were packaged in plastic and aluminum containers, frozen at −20°C, and thawed with microwave oven, hot water (100°C), and at ambient condition for four cycles of 5‐day interval. After each cycle, chemical compositions of the samples were determined using AOAC methods. Data were analyzed using ANOVA at P = 0.05. Moisture, protein, fat, crude fiber, ash, and carbohydrate contents of the freeze–thawed soups were 63.6–88.6%, 3.6–8.8%, 1.0–6.1%, 0.8–1.2%, 1.8–4.6%, and 0.9–15.6%, respectively. Mineral contents were iron (5.0–6.8 mg/100 g), calcium (68.1–190.8 mg/100 g), sodium (144.4–231.7 mg/100 g), potassium (200.4–302.1 mg/100 g), and phosphorus (228.0–337.2 mg/100 g). Vitamins were vitamin A (29.5–59.9 mg/100 g), vitamin B (10.1–36.4 mg/100 g), and vitamin E (28.4–90.2 mg/100 g). Microwave‐thawed plastic soups had limited nutritional losses when compared with other thawing methods, and should not be extended beyond the third cycle because of increasing reduction in fat and protein, indicating deterioration.