bluuebunny/crossref_metadata_2025_split huggingface dataset:
Joint Incidence of Asthma and Rhinitis in Macedonia
Authors: Zdraveska M , Dimitrievska D , Todevski D , Gjorcev A , Janeva E , Pavlovska I , Zafirova-Ivanovska B 
Published: April 2015

The concept of “united airways disease”, based on many similar features and mutual interactions in the pathogenesis of asthma (A) and rhinitis (R), has led to an integral approach to their management. We conducted this study to determine the quantity of the problem of joint incidence of A and R in R. Macedonia, and, perhaps to obtain information on a potential causative effect of the two diseases.Three hundred eighty six patients, who presented with wheezing and/or upper respiratory symptoms at the Pulmology and Allergy Clinic, Skopje, were included during a period of 48 months. The presence of bronchial hyperreactivity – BHR (positive histamine challenge), atopy (prick test to seasonal or perennial inhaled allergens), rhinitis symptoms (such as nasal secretion and obstruction) and X-ray of paranasal sinuses was registered by a specially designed questionnaire. R was diagnosed in 106 of the subjects (27.5%), and A in 280 (72.5%). Among the patients with A, co-incidence with R was found in 219 (76.5%). Including X-ray of paranasal sinuses to the diagnostic protocol increased this percentage to over 90% (256 patients). From the 219 patients with A and R together, 127 (57.99%) had positive atopy. On the other hand, 19 (18.0%) of the rhinitis-only patients had positive BHR without asthma symptoms. The follow up of the rhinitis patients with positive BHR revealed 4 patiets who developed asthma within 36 months, but this was also the case with 2 of the subjects with R and negative BHR. In conclusion, the co-incidence of A and R in our material is 78.21%, or 91.4% (including sinusitis); a greater co-existence of A and R is found in atopic patients. The patients with allergic R are at high risk for developing A and should be monitored in the future and the R symptoms should be adequately treated in order to minimize the risk for developing asthma.
Characterization, treatment, and outcome of bacterial cholecystitis and bactibilia in dogs
Authors: Lawrence Yuri A. , Ruaux Craig G. , Nemanic Sarah , Milovancev Milan 
Published: April 2015

Abstract
Objective—To characterize historical, clinicopathologic, ultrasonographic, microbiological, surgical, and histopathologic features of bacterial cholecystitis and bactibilia in dogs and evaluate response to treatment and outcomes in these patients.
Design—Retrospective case-control study.
Animals—40 client-owned dogs (10 with bacterial cholecystitis on histologic analysis or bactibilia on cytologic examination [case dogs] and 30 without bactibilia [controls]) evaluated at a veterinary teaching hospital between 2010 and 2014.
Procedures—Signalment, history, clinicopathologic findings, ultrasonographic features, microbiological results, surgical findings, histopathologic changes, treatments, and outcomes of case dogs were derived from medical records and summarized. Demographic and clinicopathologic data and ultrasonographic findings were compared between case and control dogs. Relationships among prior antimicrobial treatment, sediment formation in the gallbladder, presence of immobile biliary sludge, and presence of bactibilia or bacterial cholecystitis were assessed.
Results—No finding was pathognomonic for bactibilia or bacterial cholecystitis in dogs. Case dogs were significantly more likely to have immobile biliary sludge and had a greater degree of biliary sediment formation than did control dogs. All case dogs for which gallbladders were examined histologically (6/6) had bacterial cholecystitis. Five of 10 case dogs were Dachshunds. Medical or surgical treatment resulted in good outcomes.
Conclusions and Clinical Relevance—Bactibilia and bacterial cholecystitis were important differential diagnoses in dogs with signs referable to biliary tract disease. Dachshunds were overrepresented, which may suggest a breed predisposition. Cytologic evaluation of bile should be considered in the routine assessment of dogs with hepatobiliary disease if immobile biliary sludge is present. (J Am Vet Med Assoc 2015;246:982–989)
Introduction of a metabolic joint asymmetry score derived from conventional bone scintigraphy
Authors: Khalaf F. , Seidel M. , Al Zreiqat A. , Wilsmann-Theis D. , Simon B. , Biersack H.-J. , Sabet A. , Ezziddin S. 
Published: April 2015

SummaryAim: Clinical differentiation of psoriatic arthritis (PsA) and rheumatoid arthritis (rA) based on the pattern of joint involvement can be difficult; the frequent form of PsA with polyarthritis of the peripheral joints may sometime resemble rA. We investigated a metabolic joint asymmetry score (MJAS), reflecting the overall asymmetric joint involvement on conventional bone scintigraphy, for differentiating PsA from rA in patients presenting with peripheral polyarthritis. Patients, methods: 106 patients (n = 61, PsA; n = 45, rA) with peripheral polyarthritis (≥ 5 joints) as well as 26 control subjects with no history of chronic joint disorders were analyzed. The intensity of articular 99mTc-MDP uptake in 40 peripheral joint pairs was scored regarding the bilateral difference of each joint based on a scale of 0–2 (no significant, moderate, and marked asymmetry, respectively). The patient's MJAS was defined as the sum of uptake difference scores of all joint pairs. The association of MJAS with the underlying condition (Psoriasis criteria, Revised Criteria of the ACR) was examined. Results: 5280 peripheral joint pairs were investigated. There was no significant difference in the total number of involved joints in PsA 15.0 ± 8.2 versus rA 17.5 ± 8.8 patients (p = 0.132), but significantly less involvement in the control group (6.7 ± 5.0, p < 0.001). MJAS was markedly higher in PsA (17.0 ± 9.6) than in rA (4.8 ± 3.9, p < 0.001), and correlated with the total number of involved joints in PsA (r = 0.516, p < 0.001), but not in rA (r = 0.078, p = 0.380). The MJAS disparity between PsA and rA persisted after exclusion of the DIP joints (14.4 ± 7.7 vs. 4.4 ± 3.3; p<0.001). Conclusions: The new reproducible semi-quantification method for the asymmetry of metabolic joint involvement permits differentiation of psoriatic from rheumatoid peripheral arthritis with MJAS being markedly higher in patients with PsA as compared to rA patients. The score may offer an effective complementary tool for characterizing patients with peripheral polyarthritis.
Correlation between staphylococcal biofilm formation in vitro and potential for catheter-related infections
Authors: Oufrid Salwa , Ghazlane Zineb , Jamali Loubna , El Otmani Fatima , Talmi Mustapha , Elmdaghri Naima , Zerouali Khalid , Timinouni Mohammed 
Published: April 2015

Introduction: The present study evaluated biofilm-forming capacity and the presence of both icaA and icaD genes among staphylococcal strains isolated from catheter-related infections and blood culture. Methodology: Ninety staphylococcal isolates, which included 45 strains of catheter infection origin and 45 strains of blood culture origin, were tested for their ability to produce biofilm using microtiter test plates and a catheter test. The presence of icaA and icaD genes was determined by polymerase chain reaction (PCR). Results: Of the 45 strains of catheter infection origin, 22 (48.88%) formed biofilm. In comparison, only 10 (22.22%) of the 45 strains of blood culture origin formed biofilms. Similar results were obtained from both the microplate test and catheter test. In the 32 strains that were able to form biofilm, 30 were positive for icaA and icaD genes, and the remaining 2 strains were negative for both genes. Fifteen staphylococcal strains of all origins presented only the icaA locus and did not form biofilm. In 88 of 90 tested strains (97.77%), there was a positive correlation between biofilm production and presence of icaA and icaD genes, and between no biofilm production and absence of both or only one of the tested genes. Conclusions: The ability of staphylococcal isolates to form biofilm in vitro appears to be an indication of a virulence trait that enhances the ability of isolates to cause catheter-related infections. In addition, our results indicate an important role of ica genes and phenotypic variability of biofilm production as virulence factors in staphylococcal infections.
Genotyping methods for monitoring the epidemic evolution of A. baumannii strains
Authors: Ahmed Salman Shaheer , Alp Emine 
Published: April 2015

Acinetobacter baumannii is clustered with other phenotypically similar species into what has commonly become known as the ACB complex: A. calcoaceticus, A. pittii and, A. nosocomialis. The ecology and pathology of most of these species are not well understood, mainly because current specific phenotypic techniques have, to date, been insufficient. This has inhibited both the precise identification of, as well as the ability to discriminate between, these clinically important and closely related Acinetobacter strains. However, new genotypic methods have greatly enhanced our capacity to identify the ACB complex. This has resulted in the implementation of more rational infection control programs. Several genotypic identification methods are explored in this study, including non-polymerase chain reaction (PCR)-based and PCR-based methods. These methods include ribotyping, pulsed-field gel electrophoresis, 16S rRNA identification, multilocus sequence typing, single locus sequence typing, restriction fragment length polymorphism analysis, restriction analysis of 16S-23S rRNA intergenic spacer sequences, rapid amplification of polymorphic DNA, and repetitive extragenic palindromic PCR; however, there is no current single ideal genotyping method. Each one has its own advantages and disadvantages. With this in mind we reviewed current and new genotyping methods used to characterize the Acinetobacter species.
Museo pseudepigrafo, un ponte artificiale tra Orfeo ed Eleusi
Authors: De Cicco Pasqua 
Published: April 2015

Le but principal de cet article est de répondre à un manque d’études détaillées sur Musée orphique. La valeur de sa poésie et les problèmes liés à sa généalogie ont été en effet très peu étudiés par les scientifiques. Cette figure a été inventée vers la fin du VI e siècle av. J.-C. comme un complément de la tradition orphique et une personnification d’un certain type de littérature. Le chresmologue Onomacrite publia une collection de ses oracles, qu’Hérodote considéra moins fiables que Bakis : d’où, probablement, le jugement de Pausanias sur la poésie de Musée. Pendant la période classique, Musée a été pourvu d’une généalogie et lié à Eumolpos, l’objectif étant de rattacher la tradition orphique à celle d’Éleusis. La structure de cette généalogie a produit un débat entre Athènes et les Eumolpides, ces derniers n’acceptant pas la soumission de leur fondateur. La conséquence de ce débat est la multiplication des niveaux de généalogie de Musée à partir du IV e siècle av. J.-C.
Le mystérieux doublement de la rançon gauloise et le procès de Manlius Capitolinus
Authors: Poulle Bruno 
Published: April 2015

Lors de la prise de Rome par les Gaulois, la possibilité d’une réduction pondérale de la livre permet d’expliquer trois faits historiques. D’une part, alors que le montant attesté de la rançon gauloise était de mille livres, on constata en 52 av. J.-C. un mystérieux doublement de l’or déposé au Capitole. D’autre part, le différend entre Brennus et les Romains lors de la pesée est le signe que la livre n’avait pas la même valeur pour les deux parties. Enfin, les accusations portées contre Manlius Capitolinus et le soutien que lui apportèrent les débiteurs s’expliquent par cette dévaluation.
Goutte de Vies, un collectif singulier ...
Authors: Cevenes Yves , Velut Nicolas 
Published: April 2015

Goutte de Vies, le collectif des Morts de la rue 31, est une association qui, en s’occupant de la mort de ceux dont on ne s’occupe pas, tente de s’opposer à la disparition complète, allant jusqu’à l’effacement mémoriel, des « exclus » comme but ultime d’un long processus qui commence bien avant la mort biologique du sujet en état d’exclusion. Par son travail de soutien de ceux qui restent et de support d’un témoignage, elle est aussi le réceptacle des effets de revitalisation et de remise en récit d’histoires un temps interrompues qui sont autant d’effets subjectifs de la disparition de « l’exclu ».
Histoire d’en parler
Authors: Estivals François , Delerue Marie 
Published: April 2015

L’ asp Toulouse, membre de l’Union nationale des asp , accompagne les personnes confrontées aux périodes difficiles de la maladie grave et de la fin de vie ainsi que les personnes en deuil. Elle compte, à Toulouse, une centaine de bénévoles. Elle intervient au domicile ou en institution pour les patients et leur famille dans une démarche interdisciplinaire. Pour les personnes en deuil, l’ asp propose une ligne d’écoute ainsi que des entretiens individuels, et des groupes de partage et d’entraide animés par des bénévoles spécialement formés. Les groupes de partage et d’entraide pour les personnes endeuillées ont lieu au local de l’association pour certains (en particulier pour le deuil périnatal) et pour d’autres, dans le cadre du dispositif « Histoire d’en parler », à l’hôpital La Grave (Toulouse). Ils permettent de découvrir que l’on peut, en prenant la parole devant les autres, se situer en acteur de sa propre histoire, trouver un écho à sa souffrance chez ceux qui ont vécu des situations similaires, être aidé par les autres et les aider. Les échanges très libres, dans la résonance aux mots de l’autre, rassurent chacun sur la normalité du vécu de deuil. Le groupe est aussi un « sas » social pour rompre l’isolement.
Vie et mort à la maternité. Témoignages de soignants
Authors: Metge Daniel , Collas Ève , Puyuelo Laurent 
Published: April 2015

Un mort à la maternité : cela peut paraître inconcevable de nos jours. Cet article retrace le vécu de l’équipe de la maternité de la clinique de l’Union (Toulouse) face à l’annonce d’un décès fœtal. À la fois ensemble mais aussi chacun de son côté. L’accompagnement d’une parturiente dans cette naissance d’un mort-né est vécu ici du côté soignant. Médecin, sage-femme, psychologue racontent leurs vécus personnels : partagés entre soins, souffrance et solitude. Chacun à sa place mais dans un travail d’équipe tenant compte de la singularité de chaque situation.
Mourir en ehpad
Authors: Le Gall Joëlle 
Published: April 2015

À quelles mains livrerons-nous demain nos derniers instants de vie ? Qui pourra nous aider, nous aimer, pour accompagner ce passage de l’autre côté du miroir ? Aurons-nous le choix de nos derniers moments et qui sera là pour nous rassurer et caresser notre main, notre front ? L’enfant qui voit le jour est condamné inévitablement à mourir un jour, notre vie c’est aussi notre mort. Pour les non-croyants, c’est le néant, pour d’autres, la lumière divine. Ce passage, notre dernier salut à la vie, sachons le protéger et le respecter pour le bien de l’humanité.
La filière éducative : quel genre de travail ?
Authors: Pech Rémi , San Martin Evangelina 
Published: April 2015

À l’aide d’une étude menée auprès de stagiaires de la filière éducative, nous avons voulu mettre au jour les représentations sociales que peuvent avoir des amp , me et es au tout début de leur formation à propos de l’exercice de leur future profession et en particulier en ce qui concerne leurs aptitudes « naturelles » liées à leur statut d’homme ou de femme. Ainsi, au travers de cette étude, il s’agit bien de questionner ce qui, de fait, contribue à la formation des comportements et des attitudes des futurs professionnels.
Making Life: Work as a Locus of Feminist Rehearsal
Authors: Shields Tanya 
Published: April 2015

Abstract
This essay examines representations of labor in Caribbean literature through the lens of feminist rehearsal, a term I have conceived, to argue that work is a central location in understanding Caribbean women’s belonging and power and that it connects them to the sexual and political economies of the region. With feminist rehearsal, I employ the same trope from several vantage points to reach a fuller understanding of the implications of the relational and symbolic power in Meiling Jin’s "Victoria" and Lorna Goodison’s "Bella Makes Life." These short stories, seen through/as feminist rehearsal, highlight the ways in which work, race, class, and belonging intersect in the Caribbean.
Seismic source functions from free‐field ground motions recorded on SPE: Implications for source models of small, shallow explosions
Authors: Rougier Esteban , Patton Howard J. 
Published: April 2015

AbstractReduced displacement potentials (RDPs) for chemical explosions of the Source Physics Experiments (SPE) in granite at the Nevada Nuclear Security Site are estimated from free‐field ground motion recordings. Far‐field P wave source functions are proportional to the time derivative of RDPs. Frequency domain comparisons between measured source functions and model predictions show that high‐frequency amplitudes roll off as ω− 2, but models fail to predict the observed seismic moment, corner frequency, and spectral overshoot. All three features are fit satisfactorily for the SPE‐2 test after cavity radius Rc is reduced by 12%, elastic radius is reduced by 58%, and peak‐to‐static pressure ratio on the elastic radius is increased by 100%, all with respect to the Mueller‐Murphy model modified with the Denny‐Johnson Rc scaling law. A large discrepancy is found between the cavity volume inferred from RDPs and the volume estimated from laser scans of the emplacement hole. The measurements imply a scaled Rc of ~5 m/kt1/3, more than a factor of 2 smaller than nuclear explosions. Less than 25% of the seismic moment can be attributed to cavity formation. A breakdown of the incompressibility assumption due to shear dilatancy of the source medium around the cavity is the likely explanation. New formulas are developed for volume changes due to medium bulking (or compaction). A 0.04% decrease of average density inside the elastic radius accounts for the missing volumetric moment. Assuming incompressibility, established Rc scaling laws predicted the moment reasonable well, but it was only fortuitous because dilation of the source medium compensated for the small cavity volume.
Regioselektive Ringöffnungspolymerisation einer Polyhydroxycarbonsäure zu einem nanoskaligen Trägermaterial mit pH‐abhängiger Stabilität und verzögerter Wirkstofffreisetzung
Authors: Ewe Alexander , Jansen de Salazar Anita , Lemmnitzer Katharina , Marsch Michael , Aigner Achim , Geyer Armin 
Published: April 2015

AbstractSynthetische Polyester sind aus Monohydroxycarbonsäuren aufgebaut, um das Problem der Regioselektivität der Veresterung bei der Ringöffnungspolymerisation zu vermeiden. Im Unterschied dazu trägt der lineare Polyester BICpoly gleich vier sekundäre OH‐Gruppen pro Monomer und ist trotzdem nur über eine davon regioselektiv verestert. Sowohl bei der Synthese des tricyclischen Monomers als auch bei der Ringöffnungspolymerisation wird auf Schutzgruppen verzichtet, was BICpoly zu einem attraktiven neuen biokompatiblen Polymer macht. BICpoly‐Nanopartikel können mit niedermolekularen Wirkstoffen beladen werden oder lassen sich auch als dünne Filme auf Oberflächen abscheiden. Die Freisetzung immobilisierter Substanzen macht BICpoly zu einem attraktiven Depot zur Wirkstofffreisetzung, wie wir anhand der Beladung von BICpoly mit Farbstoffen oder dem Zytostatikum Doxorubicin zeigen. Die charakteristische pH‐Abhängigkeit des Abbaus unterscheidet BICpoly von anderen bekannten Polymeren.
C‐H‐Alkenylierungen mit Alkenylacetaten, ‐phosphaten, ‐carbonaten und ‐carbamaten durch Cobalt‐Katalyse bei 23 °C
Authors: Moselage Marc , Sauermann Nicolas , Richter Sven C. , Ackermann Lutz 
Published: April 2015

AbstractPreisgünstige Cobalt‐Katalysatoren mit N‐heterocyclischen Carbenliganden ermöglichten direkte Aren‐Alkenylierung mit einfach zugänglichen Alkenyl‐Acetaten durch regioselektive C‐H‐/C‐O‐Funktionalisierung in einer stereokonvergenten Reaktion. Der vielseitige Cobalt‐Katalysator zeigte breite Anwendbarkeit und ermöglichte somit auch die effiziente Umsetzung von Alkenylphosphaten, ‐carbonaten und ‐carbamaten bei Umgebungstemperatur.
Composite Polymer/Oxide Hollow Fiber Contactors: Versatile and Scalable Flow Reactors for Heterogeneous Catalytic Reactions in Organic Synthesis
Authors: Moschetta Eric G. , Negretti Solymar , Chepiga Kathryn M. , Brunelli Nicholas A. , Labreche Ying , Feng Yan , Rezaei Fateme , Lively Ryan P. , Koros William J. , Davies Huw M. L. , Jones Christopher W. 
Published: April 2015

AbstractFlexible composite polymer/oxide hollow fibers are used as flow reactors for heterogeneously catalyzed reactions in organic synthesis. The fiber synthesis allows for a variety of supported catalysts to be embedded in the walls of the fibers, thus leading to a diverse set of reactions that can be catalyzed in flow. Additionally, the fiber synthesis is scalable (e.g. several reactor beds containing many fibers in a module may be used) and thus they could potentially be used for the large‐scale production of organic compounds. Incorporating heterogeneous catalysts in the walls of the fibers presents an alternative to a traditional packed‐bed reactor and avoids large pressure drops, which is a crucial challenge when employing microreactors.
The Addition of Nitriles to a Molecular Digermene: Reversible Addition and Comparison to Surface Reactivity
Authors: Hardwick Julie A. , Baines Kim M. 
Published: April 2015

AbstractThe addition of acetonitrile, propionitrile, and acrylonitrile to tetramesityldigermene was investigated and compared to the addition of acetonitrile and acrylonitrile to germanium dimers on the Ge(100)‐2×1 surface. In each case, a 1,2,3‐azadigermetine was formed as the major product. As on the surface, the addition of nitriles to digermenes was found to be reversible, providing the first example of a reversible cycloaddition of a ditetrelene. No evidence for a six‐membered cyclic ketenimine was observed as noted in the surface chemistry, suggesting that the surface ketenimine might only form between two adjacent dimers rather than on a single dimer. The comparative chemistry provides important insights that are not possible by the independent study of each system.
Single‐Walled Carbon Nanotube/Metalloporphyrin Composites for the Chemiresistive Detection of Amines and Meat Spoilage
Authors: Liu Sophie F. , Petty Alexander R. , Sazama Graham T. , Swager Timothy M. 
Published: April 2015

AbstractChemiresistive detectors for amine vapors were made from single‐walled carbon nanotubes by noncovalent modification with cobalt meso‐arylporphyrin complexes. We show that through changes in the oxidation state of the metal, the electron‐withdrawing character of the porphyrinato ligand, and the counteranion, the magnitude of the chemiresistive response to ammonia could be improved. The devices exhibited sub‐ppm sensitivity and high selectivity toward amines as well as good stability to air, moisture, and time. The application of these chemiresistors in the detection of various biogenic amines (i.e. putrescine, cadaverine) and in the monitoring of spoilage in raw meat and fish samples (chicken, pork, salmon, cod) over several days was also demonstrated.
Catalytic Enantioselective Intramolecular Aza‐Diels–Alder Reactions
Authors: Min Chang , Lin Chih‐Tsung , Seidel Daniel 
Published: April 2015

AbstractA readily available chiral Brønsted acid was identified as an efficient catalyst for intramolecular Povarov reactions. Polycyclic amines containing three contiguous stereogenic centers were obtained with excellent stereocontrol in a single step from secondary anilines and aldehydes possessing a pendent dienophile. These transformations constitute the first examples of catalytic enantioselective intramolecular aza‐Diels–Alder reactions.