bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Lung-Restricted Marker Napsin A Is Highly Expressed in Clear Cell Carcinomas of the Ovary
Authors: Kandalaft Patricia L. , Gown Allen M. , Isacson Christina 
Published: November 2014

Abstract

Objectives:
We recently observed expression of the “lung” marker napsin A in ovarian clear cell carcinomas and therefore sought to determine the extent of napsin A expression in a subset of ovarian neoplasms.

Methods:
We identified an archival series of ovarian clear cell carcinomas (n = 36), serous borderline tumors (n = 21), high-grade serous carcinomas (n = 37), and endometrioid adenocarcinomas (n = 29). Using standard immunohistochemical techniques on whole sections of formalin-fixed, paraffin-embedded specimens, we employed a panel of antibodies: napsin A (IP64), estrogen receptor (SP1), WT-1 (6F-H2), PAX-8 (BC12), and TTF-1 (SPT24).

Results:
Thirty-six of 36 clear cell carcinomas showed napsin A expression, typically in a uniform pattern. None of the serous borderline tumors or high-grade serous carcinomas manifested napsin A expression. Napsin A was expressed in three (10%) of 29 endometrioid adenocarcinomas, generally in a focal pattern.

Conclusions:
Our study showed that napsin A is an extremely sensitive (100%) marker of ovarian clear cell carcinomas and exhibits very high specificity (100%) in distinguishing clear cell carcinomas from high-grade serous carcinomas and serous borderline tumors and 90% specificity in discriminating clear cell carcinomas from endometrioid carcinomas.
Diverse Clinicopathologic Features in Human Herpesvirus 8–Associated Lymphomas Lead to Diagnostic Problems
Authors: Courville Elizabeth L. , Sohani Aliyah R. , Hasserjian Robert P. , Zukerberg Lawrence R. , Harris Nancy L. , Ferry Judith A. 
Published: November 2014

Abstract

Objectives:
Human herpesvirus 8 (HHV8)–associated lymphomas are uncommon, mainly affect men infected with the human immunodeficiency virus (HIV), and usually have a poor prognosis. We sought to characterize the HHV8+ lymphomas seen at our institution since the mid-1990s.

Methods:
We identified 15 patients with HHV8-associated lymphomas and evaluated their clinical and pathologic features.

Results:
Diagnoses included primary effusion lymphoma (PEL) (n = 2), extracavitary PEL (n = 8), intravascular large B-cell lymphoma (n = 1), HHV8+ plasmablastic microlymphoma (n = 3), and germinotropic lymphoproliferative disorder (GLD) (n = 1). The case of GLD progressed to a high-grade HHV8+ Epstein-Barr virus–positive lymphoma, an evolution that has not been previously reported. Four patients were HIV−(three from an HHV8-endemic area). Potentially misleading pathologic features in our series of extracavitary PEL included classic Hodgkin lymphoma–like features, lymph node sinus involvement, and T-cell antigen expression.

Conclusions:
HHV8-associated lymphomas can be clinically and pathologically heterogeneous, with features that may lead to misdiagnosis as other types of lymphoma.
Are we there yet? The role of continuous assessment in musical theatre training
Authors: Harrison Scott , Sabey Paul , O’Bryan Jessica 
Published: November 2014

Abstract
This article seeks to interrogate aspects of assessment practices in musical theatre. Practices in the training of musical theatre students are rarely a source for reflection, and this project sought to unveil some of the processes of learning, teaching and assessment in a new musical theatre degree. The larger project on which this article is based sought to develop and evaluate assessment protocols that assisted in facilitating practices with a stronger alignment with the professional realities of musical theatre. The data for this research consists of perceptions of students and their lecturers in relation to the implementation of a continuous assessment regime in a musical theatre degree in Australia. The assessment process is designed to provide students with regular commentary about their progress. In addition to end-of-semester exams, weekly marks are awarded for approximately twenty sub-activities within the broad areas of acting, dance, performance project, singing and speech. In addition, this means of assessment is located within a degree structure that employs a sliding scale across three years: students are assessed through formative assessment in the early years, and summative in the later years of the degree. Through individual interviews with staff and students, the efficacy of this assessment process was documented. Staff members who worked with students in the programme were interviewed to ascertain the strengths and weaknesses of such an approach. Students were interviewed to determine whether they believed it assisted them in both their learning and in achieving goals during and beyond the degree. An action research cycle was initiated and the findings demonstrate a relative degree of agreement between expectations of participants in the course and the proposed outcomes at the end of the degree. These findings, combined with artefacts from the programme and previously reported student perceptions, are presented as a model that may provide the potential for replication in other training programmes that seek to prepare students for the realities of a career in the creative and performing arts.
Last chances and long journeys: Rocky and Violet come to Broadway
Authors: Lodge Mary Jo 
Published: November 2014

Abstract
In this performance review, the author considers two new musicals premiering on Broadway in the spring of 2014: Rocky, the stage adaptation of Sylvester Stallone’s 1976 movie, by Thomas Meehan and Stephen Flaherty, and Violet, the adaptation of Doris Betts’ short story ‘The Ugly Pilgrim’, by Brian Crawley and Jeanine Tesori. Although in theme and subject matter the author finds certain similarities between these shows, the productions themselves play out quite differently and offer an interesting comparative analysis.
Reviews
Authors: Hetra Michael , Thomaidis Konstantinos , Warner Rebecca , Yuh Ji Hong (Kayla) , Clum John M. 
Published: November 2014

Abstract
Dangerous Rhythm: Why Movie Musicals Matter, Richard Barrios (2014) New York: Oxford University Press, 288 pp., ISBN: 9780199973842, h/bk, £22.99
The Legacy of Opera: Reading Music Theatre as Experience and Performance, Dominic Symonds and Pamela Karantonis (2013) Amsterdam and New York: Rodopi, 269 pp., ISBN: 9789042036918, p/bk, $78
West End Broadway: The Golden Age of the American Musical in London, Adrian Wright (2012) Woodbridge: The Boydell Press, 376 pp., ISBN: 9781843837916, h/bk, £25
A Million Miles from Broadway: Musical Theatre beyond New York and London, Mel Atkey (2012) Vancouver and London: Friendlysong Books, 296 pp., ISBN: 9780991695706, p/bk, $23.60
Love Song: The Lives of Kurt Weill and Lotte Lenya, Ethan Mordden (2012) New York: St. Martins, 334 pp., ISBN: 9780312676575, h/bk, $25.95
Price Disclosure Rules and Consumer Price Comparison
Authors: Stühmeier Torben 
Published: November 2014

AbstractSearch frictions are regarded as a major impediment to active competition in many markets. In some markets, such as financial and retail gasoline, governments and consumer protection agencies call for compulsory price reporting. Consumers could then more easily compare the firms’ offers. We show that for a given level of price comparison, mandatory price reporting indeed generally benefits consumers. Such regulation, however, feeds back into firms’ strategies, resulting in lower levels of price comparison in equilibrium. This effect may dominate so that the regulation leads to higher expected market prices.
Comparison of chemical composition and biological activities of Seseli rigidum fruit essential oils from Serbia
Authors: Ilić Marija D. , Jovanović Vesna P. Stankov , Mitić Violeta D. , Jovanović Olga P. , Mihajilov-Krstev Tatjana M. , Marković Marija S. , Stojanović Gordana S. 
Published: November 2014

Abstract
Plants from genus Seseli, have been widely used in European traditional medicine, exhibiting antibacterial, antifungal, insect repellent, emmenogogue, antiflatulence, anti-inflammatory, antinociceptive, anti-tumor, antirheumatic activities and protective effect on human lymphocytes DNA. They usually grow on mountain rocky terrains. Part of their habitat on Vidlic Mountain, located in South-east Serbia, was struck with a large wildfire. Seseli rigidum fruit essential oils (from post fire and control areas) compositions were analyzed by GC and GC-MS, identifying monoterpenes α-pinene and sabinene as most abundant. Statistical tests showed a non-significant difference in chemical composition of these two oils, but a significant difference in comparison with the herb from a geographically different origin. Antimicrobial tests showed strong activities of the oils against tested bacteria, thus confirming its administration in various inflammation processes as a quite effective remedy. Applying DPPH. and ABTS+. radical scavenging and total reducing Fe(III) to Fe(II) power assays, antioxidant characteristics of both studied essential oils were estimated as weak, though of close values. Seseli rigidum fruit essential oil was proven as a potent inhibitor of human and horse serum cholinesterase, recognizing its possible application as neural protective agent
Immunoactive ionic liquids based
on 2-hydroxyethylamines and 1-R-indol-3-ylsulfanylacetic acids. Crystal
and molecular structure of immunodepressant tris-(2-hydroxyethyl)ammonium
indol-3-ylsulfanylacetate
Authors: Mirskova Anna N. , Adamovich Sergey N. , Mirskov Rudolf G. , Kolesnikova Olga P. , Schilde Uwe 
Published: November 2014

Abstract
Immunoactive ionic liquids (2-hydroxyethyl)ammonium 1-R-indol-3-ylsulfanyl-acetates HN+R1R2(CH2CH2OH) ∙ -O(O)CCH2S-Ind-R3-1 (1-5), were synthesized by the reaction of (2-hydroxyethyl)amines with indol-3-ylsulfanylacetic- or 1-benzylindol-3-ylsulfanylacetic acid. 1: R1 = R2 = CH2CH2OH, R3 = H; 2: R1 = СН3,R2=CH2CH2OH, R3 = H; 3: R1 = R2 = CH3, R3 = H; 4: R1 = R2 = CH2CH2OH, R3 = СH2С6Н5; 5: R1 = СН3; R2 = CH2CH2OH; R3 = СH2С6Н5. The structure of each compound was elucidated by IR, NMR 1H, 13С, and 15N techniques and their composition was confirmed by elemental analysis. The crystal structure of tris-(2-hydroxyethyl) ammonium indol-3-ylsulfanylacetate was investigated by X-ray diffraction analysis. Immunoactive properties of the title compounds were screened.
Chemical profile and antimicrobial activity of extractable compounds of Betula litwinowii (Betulaceae) buds
Authors: Isidorov Valery A. , Bagan Róża , Szczepaniak Lech , Swiecicka Izabela 
Published: November 2014

Abstract
In spite of the long history of therapeutic use of buds from different birch species in folk medicine the existing information on their chemical composition is insufficient. The main goal was to develop a method for GC-MS determination of the chemical profile of birch buds as well as their antimicrobial activity. 150 substances of different classes were identified in Betula litwinowii buds. The volatile elements of the buds were mainly represented by sesquiterpene compounds. Ether extracts also contained other biologically active components such as flavonoids and triterpenoids. However, a particular feature of this fraction was the high content of sesquiterpene phenylpropenoids, including esters of ferulic and caffeic acids with caryophyllene-type alcohols that had not been previously found in any biological samples. Apart from carbohydrates, a series of free amino acids were detected in methanol extracts. The antimicrobial activity of the ether extracts of the buds was observed against all of the microorganisms tested, with MIC values from 0.04 to 0.08 mg mL-1 for Gram-positive bacteria and Candida albicans. However, their inhibitory activities against tested Gram-negative bacteria were rather occasional.
Modular p-adic L-functions attached to real quadratic fields
and arithmetic applications
Authors: Greenberg Matthew , Seveso Marco Adamo , Shahabi Shahab 
Published: November 2014

Abstract
Let

f
∈

S

k
0

+
2

⁢

(

Γ
0

⁢

(

N
⁢
p

)

)

${f\in S_{k_{0}+2}(\Gamma_{0}(Np))}$

be a normalized N-new eigenform with

p

∤
N

${p\,{\nmid}\,N}$

and such that

a
p
2

≠

p

k
0

+
1

${a_{p}^{2}\neq p^{k_{0}+1}}$

and

ord
p

⁡

(

a
p

)

<

k
0

+
1

${\operatorname{ord}_{p}(a_{p})<k_{0}+1}$

. By Coleman’s theory, there is a p-adic family

𝐅

${\mathbf{F}}$

of eigenforms whose weight

k
0

+
2

${k_{0}+2}$

specialization is f. Let K
be a real quadratic field and let ψ be an unramified character of

Gal
⁡

(

K
¯

/
K

)

${\operatorname{Gal}(\overline{K}/K)}$

. Under mild hypotheses on the discriminant of K and the
factorization of N, we construct a p-adic L-function

ℒ

𝐅
/
K

,
ψ

${\mathcal{L}_{\mathbf{F}/K,\psi}}$

interpolating the central critical values of the Rankin L-functions associated to the base change to K of the specializations of

𝐅

${\mathbf{F}}$

in classical weight, twisted by ψ. When the character ψ
is quadratic,

ℒ

𝐅
/
K

,
ψ

${\mathcal{L}_{\mathbf{F}/K,\psi}}$

factors into a product of
two Mazur-Kitagawa p-adic L-functions. If, in addition,

𝐅

${\mathbf{F}}$

has
p-new specialization in weight

k
0

+
2

${k_{0}+2}$

, then under natural parity
hypotheses we may relate derivatives of each of the Mazur-Kitagawa factors
of

ℒ

𝐅
/
K

,
ψ

${\mathcal{L}_{\mathbf{F}/K,\psi}}$

at

k
0

${k_{0}}$

to Bloch–Kato logarithms of
Heegner cycles. On the other hand the derivatives of our p-adic L-functions encodes the position of the so called Darmon cycles. As an
application we prove rationality results about them, generalizing theorems
of Bertolini–Darmon, Seveso, and Shahabi.
How Impressionable Were the Younger Reagan Cohorts?
Authors: Cook Zachary F. 
Published: November 2014

AbstractYounger voters today, defined as under the age of 30 and often labeled the Millennial Generation, have shown high support for Barack Obama and for certain statements about activist government. Are we witnessing some generational effect for a significant percentage of the Millennials, stemming from their growing up during impressionable years under first George W. Bush and then Obama? To study this question with a historical analogy, I use the ANES to compare under-30 cohorts under Jimmy Carter as a benchmark and then Ronald Reagan much more extensively. I find evidence consistent with categories advanced by Sears (1983). The Reagan years disproportionately shifted this age group’s symbolic attitudes, including partisanship, self-reported ideology, and approval of Reagan himself, but not most specific policy opinions. If this finding generalizes, recent events may leave a Democratic imprint on the Millennials, but their current measures of policy liberalism should not be attributed overmuch to Obama’s influence.
Deformation Behavior and Dynamic Recovery Kinetics of Ultrahigh Strength Steel BR1500HS at Elevated Temperature
Authors: Xia Yufeng , Ji Shuai , Zhang Yandong , Wu Dongsen , Quan Guozheng 
Published: November 2014

AbstractThe flow behaviors of ultrahigh strength steel BR1500HS at elevated temperature were studied by performing hot tension tests at the temperatures of 773 K, 873 K, 1023 K and 1173 K, and strain rates of 0.01 s
Modeling the Adsorption Step during Hydrogen Purification in Gas Treatment Application
Authors: Belgacem Balsam , Chlendi Mohamed , Bagane Mohamed 
Published: November 2014

Abstract
The present work is interested in modeling the adsorption step for the process of Pressure Swing Adsorption (PSA) for hydrogen purification. This work aims at modeling the adsorption of one or more compounds in a mixture at different pressures ranging from 8 to 20 bars at ambient temperature. The flow was presented by the piston model with an axial dispersion. The equilibrium isotherm was expressed by the Langmuir model for the mono-component adsorption and the model of Langmuir extended for the multi-component adsorption. Moreover, two models of kinetic transfer between the gaseous and solid phases were considered, the first-order model based on the approximation of the Linear Driving Force (LDF) and a sophisticated model which is the Surface Diffusion model (SD). As a first step, the CH4/H2 mixture adsorption on activated carbon was studied. In a second step, the adsorption of CH4/CO2/H2 on activated carbon and of CH4/N2/H2 on a 5A° molecular sieve was studied taking into consideration an interaction parameter for the extended Langmuir model. The simulation results obtained after the resolution of the equations of the model in a developed program, compared with the experimental results from previous works, show a rather satisfactory agreement on the level of stoichiometric time and kinetic mass transfer.
Improved Load Compensation using Harmonic Compensator in dq0 Current Controller for DSTATCOM
Authors: Geddada Nagesh , Mishra Mahesh Kumar 
Published: November 2014

Abstract
This paper presents distribution static compensator (DSTATCOM) with dq0 current controller and sine pulse width modulation (SPWM) switching for compensation of unbalanced nonlinear load in distribution system. DSTATCOM, connected in parallel to load at the point of common coupling (PCC), is used for supplying reactive and harmonic components of load current demand. This dq0 current controller is implemented in synchronous reference frame (SRF) rotating at fundamental frequency and consists of harmonic compensation (HC) regulator along with proportional integrator (PI) regulator. HC regulator is realized by number of sinusoidal signal integrators (SSIs) in parallel. The SSI provides high gain for tuned harmonic frequency and helps in minimizing filter current tracking error while compensating for load harmonic currents. Zero-axis controller, which compensates load neutral current and helps in obtaining balanced utility currents, is provided along with d, q controllers. SPWM switching generates inverter gating pulses at constant frequency, which reduces stress levels on VSI switches and simplifies the design of interface filter. Simulation studies of DSTATCOM load compensation with dq0 current controller are carried out in Matlab/Simulink and experimental verification is done using dSpace 1104 with Matlab real-time interface (RTI).
The Roles and Involvement of Local Government Human Resource Professionals in Coastal Cities Emergency Planning
Authors: Mann Stacey Cole , Islam Tanveer 
Published: November 2014

AbstractAcross the US, coastal cities are threatened by many different man-made and natural hazards. From oil spill to hurricanes, tsunamis or coastal flooding, these cities should be prepared for emergency situations and should have well-organized emergency plans for their citizens. As a department that has contact with local government employees, human resource (HR) professionals understand the concepts that are important in times of crisis, including benefits management, training and development, and compensation. From mitigation to recovery, employees are vital to planning and responding to an emergency, and in a time when local government is focused on serving its citizens, local government human resource professionals serve those protecting those citizens – local government employees. The objective of this paper is to assess the roles and involvement of local government human resource professionals in emergency planning in coastal cities nationwide. Using responses collected from HR professionals in coastal cities with populations of 50,000 – 249,999, this paper investigates common HR issues included in emergency plans. Based on the analysis of their responses, gaps are identified and recommendations are made of ways in which human resources can contribute more effectively towards emergency planning for coastal cities.
Summation of smooth functions of two variables with perturbed Fourier coefficients
Authors: Solodky Sergey G. , Sharipov Kosnazar K. 
Published: November 2014

Abstract
The present paper is devoted to the problem of
recovering smooth functions from their Fourier coefficients. We
consider the functions of two variables. Herewith this problem is
ill-posed. The problem is studied in the case of given smoothness of
the functions as well as when a parameter of smoothness is supposed
to be unknown.
Effect of blood on ROM diagnosis accuracy of PAMG-1 and IGFBP-1 detecting rapid tests
Authors: Ramsauer Babett , Duwe Wiebke , Schlehe Bettina , Pitts Regina , Wagner Dirk , Wutkewicz Katja , Chuvashkin Dmitry , Abele Harald , Lachmann Robert 
Published: November 2014

AbstractVaginal bleeding may be present in up to 30% of patients presenting with signs and symptoms of a rupture of the fetal membranes (ROM). The presence of blood may lead to false positive results with biochemical markers. The data presented in this study came from a multi-centric prospective observational clinical study that, for the first time, systematically evaluated the performance of placental alpha microglobulin-1 (PAMG-1) and insulin-like growth factor binding protein-1 (IGFBP-1) detecting tests in 151 women with vaginal bleedings as well as signs and symptoms indicative of ROM. Our data showed better performance for the PAMG-1 compared with the IGFBP-1 detecting tests in all quality parameters evaluated. In detail, sensitivity (SN) was 97.8% (91.0%), specificity (SP) was 91.5% (75.0%), positive predictive value (PPV) was 94.6% (83.5%) and negative predictive value (NPV) was 96.4% (85.7%) for PAMG-1 tests (and IGFBP-1 tests, respectively). A major difference between both tests was related to the number of non-evaluable test results (e.g., hidden bands due to blood smear on the test strips). While 2% of all results were not evaluable for PAMG-1 tests, this artifact appeared in 11% of the results obtained with IGFBP-1 tests. This difference and also those in Specificity and PPV were statistically significant, demonstrating superiority of PAMG-1 over IGFBP-1 detecting tests. In conclusion, the PAMG-1 detecting test was significantly less susceptible to interference by blood than the IGFBP-1 detecting test.
Is pharmacologic research on pregnant women with psychoses ethically permissible?
Authors: McCullough Laurence B. , Coverdale John H. , Chervenak Frank A. 
Published: November 2014

AbstractThere is a consistent view in the literature that research on pregnant woman with psychoses is ethically questionable or impermissible. This paper provides a critical appraisal of these views by asking whether pharmacologic research on pregnant women with psychosis for maternal, fetal, and newborn benefit is ethically permissible. We examine separately the documented clinical benefits and risks to the pregnant patient, the fetal patient, and the neonatal and pediatric patient. The outcomes reported in the pertinent literature do not support the conclusion that pharmacologic management of psychosis during pregnancy results in documented, unacceptable risk to the pregnant, fetal, or neonatal patient and is therefore ethically ruled out. Claims that research on the pharmacologic management of psychosis during pregnancy is ethically impermissible because of unacceptable risk of harm to pregnant, fetal, neonatal, or pediatric patients cannot therefore be supported. Having shown that such research is permissible, we then ask what ethical considerations should guide study design. We show that Phase I studies are appropriate and can meet the requirements of the Common Rule, which are more specific than international guidance. As a matter of professionally responsible obstetric practice, pregnant women with psychoses should be included, and not be neglected, in research for both maternal and fetal benefit.