bluuebunny/crossref_metadata_2025_split huggingface dataset:
CKIP-1 Inhibits Cardiac Hypertrophy by Regulating Class II Histone Deacetylase Phosphorylation Through Recruiting PP2A
Authors: Ling Shukuan , Sun Qiao , Li Yuheng , Zhang Luo , Zhang Pengfei , Wang Xiaogang , Tian Chunyan , Li Qi , Song Jinping , Liu Hongju , Kan Guanghan , Cao Hongqing , Huang Zengming , Nie Jielin , Bai Yanqiang , Chen Shanguang , Li Yinghui , He Fuchu , Zhang Lingqiang , Li Yingxian 
Published: November 2012

Background—
Sustained cardiac pressure overload–induced hypertrophy and pathological remodeling frequently leads to heart failure. Casein kinase-2 interacting protein-1 (CKIP-1) has been identified to be an important regulator of cell proliferation, differentiation, and apoptosis. However, the physiological role of CKIP-1 in the heart is unknown.

Methods and Results—
The results of echocardiography and histology demonstrate that CKIP-1–deficient mice exhibit spontaneous cardiac hypertrophy with aging and hypersensitivity to pressure overload–induced pathological cardiac hypertrophy, as well. Transgenic mice with cardiac-specific overexpression of CKIP-1 showed resistance to cardiac hypertrophy in response to pressure overload. The results of GST pull-down and coimmunoprecipitation assays showed the interaction between CKIP-1 and histone deacetylase 4 (HDAC4), through which they synergistically inhibited transcriptional activity of myocyte-specific enhancer factor 2C. By directly interacting with the catalytic subunit of phosphatase 2A, CKIP-1 overexpression enhanced the binding of catalytic subunit of phosphatase-2A to HDAC4 and promoted HDAC4 dephosphorylation.

Conclusions—
CKIP-1 was found to be an inhibitor of cardiac hypertrophy by upregulating the dephosphorylation of HDAC4 through the recruitment of protein phosphatase 2A. These results demonstrated a unique function of CKIP-1, by which it suppresses cardiac hypertrophy through its capacity to regulate HDAC4 dephosphorylation and fetal cardiac genes expression.
Body Mass Index and Risk of Incident Hypertension Over the Life Course
Authors: Shihab Hasan M. , Meoni Lucy A. , Chu Audrey Y. , Wang Nae-Yuh , Ford Daniel E. , Liang Kung-Yee , Gallo Joseph J. , Klag Michael J. 
Published: November 2012

Background—
The obesity-hypertension link over the life course has not been well characterized, although the prevalence of obesity and hypertension is increasing in the United States.

Methods and Results—
We studied the association of body mass index (BMI) in young adulthood, into middle age, and through late life with risk of developing hypertension in 1132 white men of The Johns Hopkins Precursors Study, a prospective cohort study.

Over a median follow-up period of 46 years, 508 men developed hypertension. Obesity (BMI ≥30 kg/m
2
) in young adulthood was strongly associated with incident hypertension (hazard ratio, 4.17; 95% confidence interval, 2.34–7.42). Overweight (BMI 25 to <30 kg/m
2
) also signaled increased risk (hazard ratio, 1.58; 95% confidence interval, 1.28–1.96). Men of normal weight at age 25 years who became overweight or obese at age 45 years were at increased risk compared with men of normal weight at both times (hazard ratio, 1.57; 95% confidence interval, 1.20–2.07), but not men who were overweight or obese at age 25 years who returned to normal weight at age 45 years (hazard ratio, 0.91; 95% confidence interval, 0.43–1.92). After adjustment for time-dependent number of cigarettes smoked, cups of coffee taken, alcohol intake, physical activity, parental premature hypertension, and baseline BMI, the rate of change in BMI over the life course increased the risk of incident hypertension in a dose-response fashion, with the highest risk among men with the greatest increase in BMI (hazard ratio, 2.52; 95% confidence interval, 1.82–3.49).

Conclusions—
Our findings underscore the importance of higher weight and weight gain in increasing the risk of hypertension from young adulthood through middle age and into late life.
Time and Emergence in the Evolutionary Epic, Naturalistic Theology, and J.T. Fraser’s Hierarchical Theory of Time
Authors: Harris Paul A. 
Published: November 2012

Abstract
This paper provides a general overview of emergence, and then examines the role emergence plays in different areas of science and theology, including big history or the evolutionary epic, religious and theistic naturalism. Critical remarks on the notions of time expressed in these discourses are also provided. The paper then assesses J.T. Fraser’s hierarchical theory of time in relation to emergence, and adduces the position Fraser would take with respect to emergence. Finally, the paper concludes with a playful coda from the standpoint of a man of letters, for whom letters have an elemental importance.
A Pre-Modern Description of Emergence: Albertus Magnus on Human Foetal Development
Authors: Costa Dennis 
Published: November 2012

AbstractBoth the theory and the terminology of Albertus Magnus’s philosophical psychology in the thirteenth century bear an extraordinary resemblance to twenty-first century descriptions of emergent systems. In Albert’s description of the temporal drama of human foetal life, the emergent, ‘intellectual’ energies of humanpsychêoranimaor soul cannot be at all predicated on the material or psychic agents that give rise to them. Though standing in a real continuity with those natural, causal agents, human psyche knows itself as existing discontinuously from them and as enacting, in and through the dimension of time, kinds of knowledge and types of experience which display complex potentialities that appear to be irreducible, or, at the least, not fully measurable: in art, in science, and also in cultic action.
A Quantum Approach to the Psychosomatic Phenomenon: Co-Emergence and Time Entanglement of Mind and Matter
Authors: Uzan Pierre 
Published: November 2012

AbstractThis paper explores the philosophy of neutral monism within the framework of a generalized version of quantum theory where all references to the physical world have been relaxed. Psychic and somatic features of the individual are conceived of as co-emergent, complementary properties of an underlying, psychophysical level of reality. It is shown that their entanglement can be interpreted in terms of non-causal correlations and parameterized by time, which thus plays the role of psychophysical interface.
Millennial Politics in Modern Egypt: Islamism and Secular Nationalism in Context and Contest
Authors: Kenney Jeffrey T. 
Published: November 2012

AbstractAs a type often linked to societies in transition, millennialism provides a useful framework of analysis to understand the contestation between the two movements that shaped Egypt’s modern identity: Islamism and secular nationalism. Both movements blended political and religious form and content as they strove to unite people in a collectivist effort to create an ideal society that addressed the nation’s material and cultural needs. Indeed, millennial discourse provided a medium through which Egyptians worked out their nationalist aspirations in a religious key and envisioned their religious values and identity in nationalist form. The volatile, irrational character of millennial movements made Egypt’s postcolonial transition to modern politics fraught and uncertain. And the authoritarian trend among Egypt’s ruling secular nationalists exacerbated the situation. In the end, Egypt’s seminal Islamist movement, the Muslim Brotherhood, proved capable of reorienting itself, downplaying its millennial claims, and espousing a rational politics. Its evolution speaks to the capacity of millennial movements to transform themselves and the societies of which they are a part.
Mary’s Reincarnation and the Banality of Salvation: The Millennialist Cultus of the Lady of All Nations/Peoples
Authors: Margry Peter Jan 
Published: November 2012

Abstract
This article deals with the transnational Dutch-Canadian apparitional cultus of our Lady of All Nations/Peoples. It analyses how contemporary visionary Catholicism is influenced by religious eclecticism, esotericism, and New Age spiritualities, and how this devotion has shifted into an autonomous millennialist movement. Finding fertile soil in modern societies in socio-economic, political, and religious crisis, and due to the dwindling of existential certainties at the individual level, its ideology of “progressive millennialism” has shown itself to be a successful religious format that mobilizes devotees, even when its deviation brings the movement into conflict with the formal Church. The movement’s prophetic and millennialist views fit into a salvific system of conditionality according to which the visionary, unveiled as the reincarnation of Mary herself, will realize the new millennium if her party will fulfill certain conditions. With its new theology the Quebec movement tries to appropriate the whole Lady cultus as a vehicle for universal salvation. In this way the means for revelation and salvation are taken from the hierarchical ecclesiastical powers-that-be and situated in the “banality” of the everyday life of the reincarnated Mary. In the providential Marie-Paule Giguère, the devotees involved find an appealing prophet who is both Mary and a co-redeeming messiah, and who in the near future is supposed to realize the second millennium, framed in a new, modern cosmology, for all peoples and faiths.
Negotiating the Social Family: Migrant Live-in Elder Care-workers in Taiwan
Authors: Lin Stephen , Bélanger Danièle 
Published: November 2012

Abstract
In response to difficulties faced by families in caring for the aged, the government of Taiwan launched a foreign live-in caregiver programme in 1992. This paper draws upon literature on family, domestic work and motives for caregiving to examine how the long-term co-residence of migrant live-in elder care-workers reconfigures Taiwanese families. Our analysis, based on in-depth interviews conducted in the summer of 2009 with 20 Vietnamese migrant live-in care-workers, uses the concept of ‘social family’ to document the close emotional and quasi-familial relationships between foreign care-workers and members of Taiwanese families. Narratives shed light on the dynamics of these relationships and show the limitations of the concept. The inherent asymmetrical employer-employee power relationship remains, while workers constantly negotiate contradictory feelings and positions in the intimate sphere of the employers’ private homes. This paper emphasizes the mutual dependency that migrants experience as both workers and members of a new family. Rather than being seen as cheap, disposable labour, migrants become indispensable to the families. It is this dependency and intimacy that make them part of the family, but also continues to make them vulnerable to abuse.
On the Composition of Amos 1-2 LXX
Authors: Sibinga Joost Smit 
Published: November 2012

Abstract
For an adequate and readily verifiable description of a given text a count of the number of its words is of essential value. This article on the literary composition of Amos 1-2 LXX uses this numerical aspect as a main criterion. It is found that the author-translator frequently balances small and larger segments of his text; he favours round figures and square numbers, achieves clear and simple proportions within his composition, such as, i.a., the golden mean, and so on. He is not only a capable translator, but throughout this passage shows himself a skilful and competent craftsman, ambitious and well trained in the numerical features of ancient literary composition.
Ockham and Buridan on Epistemic Sentences: Appellation of the Form and Appellation of Reason
Authors: Panaccio Claude 
Published: November 2012

Abstract
Buridan’s theory of sentences with epistemic verbs (‘to know’, ‘to believe’, etc.) has received much attention in recent scholarship. Its originality with respect to Ockham’s approach, however, has been importantly overestimated. The present paper argues that both doctrines share crucial features and basically belong to the same family. This is done by comparing Buridan’s notion of the ‘appellation of reason’ with Ockham’s application to epistemic sentences of the general principle that a predicate always ‘appellates its form’.
Francesco Piccolomini on Prime Matter and Extension
Authors: Claessens Guy 
Published: November 2012

Abstract
This paper examines the view held by Francesco Piccolomini (1523-1607) on the relation between prime matter and extension. In his discussion of prime matter in the Libri ad scientiam de natura attinentes Piccolomini develops a theory of prime matter that incorporates crucial elements of the viewpoint adhered to by the Neoplatonist Simplicius. The originality of Piccolomini’s undertaking is highlighted by contrasting it with the ideas found in Jacopo Zabarella’s De rebus naturalibus. The case of Piccolomini shows that, in order to classify early modern metaphysical theories of prime matter, the category ‘prime matter as sheer dimensionality’ is indispensable.
Die Apokalypse-Handschrift 2846
Authors: Lembke Markus 
Published: November 2012

Abstract
Collations of test passages in all Apocalypse manuscripts not used by H.C. Hoskier showed that one of the newly discovered minuscules reflects the so-called Alexandrian texttype to a significant extent. It is the manuscript Grec. 977 of the Bibliothèque Nationale in Paris, known as 2846 in the Kurzgefaßte Liste. Concerning the agreement with the Nestle-Aland text against the Majority Text, the ranking is: A C א 2846 P47 2062 2050 2053 2329 2344 P 1611 etc. Where P47 א differ from A C, 2846 mostly agrees with A C.
τὸ ἐν λόγῳ ἰδιωτικὸν τοῦ Ἀποστόλου
Authors: Schellenberg Ryan S. 
Published: November 2012

Abstract
The interpretation of patristic testimony has become an important part of the ongoing debate regarding Paul’s formal knowledge of ancient rhetorical theory. As early as 1898, E. Norden observed that Paul‘s earliest readers frequently commented on his innocence of Greco-Roman paideia. And yet, as Margaret Mitchell more recently has shown, these very readers often praised the power of Pauline persuasion, and, what is more, identified numerous rhetorical figures and tropes in Paul’s letters. This article provides a reevaluation of the patristic testimony as well as its apologetic context. In so doing, it calls into question Mitchell’s own explanation of the apparently contradictory evidence.
Current Explanations for the Variation in Same-Sex Marriage Policies in Western Countries
Authors: Pettinicchio David 
Published: November 2012

AbstractOver the last ten years, several western countries have recognized gay marriage either by providing gay couples the same rights as heterosexual couples, or by allowing civil unions. Other western countries have not. What accounts for this variation? This paper reviews and analyzes the key demographic, institutional and cultural arguments found in the literature on the legalization of gay marriage – especially as these pertain to cross-national comparison – and raises questions about assumptions regarding the extent to which there is variation on these variables across western countries. I argue that institutional and cultural explanations are only meaningful in explaining legalization when their combinations are specified in order to shed light on favorable (or unfavorable) circumstances for policy outcomes.
Musical Taste And Social Structure In Taiwan
Authors: Marsh Robert M. 
Published: November 2012

Abstract
Research in the comparative cultural sociology of musical taste has been confined to Western societies. The present study tests hypotheses from Western research in a culturally different, East Asian society, Taiwan. The 1992 Taiwan survey asked a representative sample of the population which of ten types of music they liked or disliked. To a large extent, the Taiwan findings replicate those in the West. For example, high status, younger people are more likely to be omnivores, liking both highbrow and lowbrow music, while low status, older people tend toward the univore pole. The ten types of musical taste can be clustered into three more general, culturally distinct taste audiences.
Hope-Filled Sanctification: A Reformed Appropriation of the Theological Virtue of Hope
Authors: VandenBerg Mary L. 
Published: November 2012

Abstract
Roman Catholic scholar Josef Pieper has suggested that the Protestant teaching of salvation by grace alone promotes a type of false assurance that undermines the necessity of striving for Christlikeness in the lives of Christians. Protestants do sometimes sound as if justification and sanctification are identical therefore downplaying the importance of good works and the pilgrim character of the Christian life. Nonetheless, a proper understanding of the distinction between justification and sanctification maintains both the Reformation emphasis on grace and a robust place for human striving toward sanctification in cooperation with the Holy Spirit. Furthermore, the Thomist tradition’s understanding of the theological virtues, as interpreted by Pieper, has the potential to offer a category for understanding the striving of sanctification as the fitting action of one with the disposition of hope.
Can Public Theology Be Practised beyond the State?
Authors: Fourie Willem 
Published: November 2012

Abstract
This article reflects on the relationship between public theology and the state. It suggests that a state-centric paradigm plays a significant role in the self-understanding and practice of public theology, and that transnationalism can serve as correction to state-centrism. It argues that these concepts complement the existing discourse on glocalization in public theology. The article investigates the role of churches in the struggle against apartheid as an early example of transnationalism in public theology. The concluding section shows that transnationalism may aid the practitioners of public theology to reflect critically on its relation to the state.
Rabbinic Theology: A System
Authors: Neusner Jacob 
Published: November 2012

Abstract
Rabbinic Theology starts with a doctrine of a world order that is just and concludes with eternal life, thus presenting a simple logic that animates all the parts of its system and makes them cohere. Its generative categories prove not only imperative and irreducible but also logically sequential. Each of the four parts of the theology of Rabbinic Judaism—[1] the perfectly just character of world order, [2] indications of its perfection, [3] sources of its imperfection, [4] media for the restoration of world order and their results—belongs in its place and set in any other sequence the four units become incomprehensible. Not only so, but each proposition draws upon its predecessor and points toward its successor, forming an unfolding story that can be told in only one direction and in the dictated order and in no other way. That is the mark of a well-crafted theology, a coherent structure, a compelling system.
If you can imagine a world perfected by the tastes and aspirations of the rational mind, then you can enter into the world portrayed by the documents of Rabbinic Judaism. The writings for theology are read all together and all at once as a single coherent statement. They portray the reason why things are now as they are. And they show the logic of that reason, revealing its integrity in the working of justice throughout. The sages emphasize the perfection of the timeless, flawless creation that God forms and governs in accord with wholly rational and accessible rules. If everything fits together and works coherently, it is because, as philosophers maintain in their realm of reflection, a single, unitary logic (“logos”), the logic of monotheism comprised by the one just, therefore reasonable and benevolent God, prevails.
Landscapes of the Body in Prudentius Cathemerinon VII
Authors: Clarke Jacqueline R. 
Published: November 2012

Abstract
In his Hymn of Fasting, Cathemerinon VII, Prudentius is expounding and justifying a concept relatively unfamiliar to his audience. This article shows how he makes metaphorical use of landscape to do this, employing landscapes as external reflections of the healthiness or sickness of the soul and the state of the body. In his narration of the stories of five biblical figures who are associated with fasting, Prudentius shows how fasting detaches soul from body which then becomes part of the territory which is to be conquered; reduced to a dry and barren desert, it is miraculously revived by moisture which is produced by suffering or comes from God.
“David sang about him”: A Coptic Psalms Testimonia Collection
Authors: Albl Martin C. 
Published: November 2012

Abstract
This study analyzes a fragmentary Coptic Psalms testimonia collection (CPT), published by Charles W. Hedrick in 2006. The text lists approximately 30 events from Jesus’ life; each event is paired with a Psalms quotation understood as a prophetic witness (testimonium) to that event. The collection is creedally structured, focusing on Jesus’ birth, his passion and death, and his resurrection, ascension, and heavenly enthronement. This study situates each of the CPT’s events and testimonia in the context of early Christian testimonia literature, noting especially close connections with catechetical works such as Rufinus’ Commentary on the Apostolic Creed. Of special interest is the CPT’s quotation of Christian additions to Ps 96:10 (“on the wood”) and to Ps 51:7 (“by the blood of the wood”). Its likely life-setting is the catechesis of fifth-century Egyptian monasticism.
“Prudentius Psychomachia 317”
Authors: Summers Kirk 
Published: November 2012

Abstract
The Latin text at Prudentius, Psychomachia 317 presents some syntactical difficulties, mostly stemming from the unexpected word quia. The manuscripts and glossa vetus offer little help on the matter. Gilbert Wakefield offered a convincing solution to the problem in a note that was buried in an edition of Lucretius that he edited in 1797. No subsequent editor of Prudentius has noticed his emendation, which should be revived and included in future editions.
Current and Prospective Roles of the Arctic Council System within the Context of the Law of the Sea
Authors: Molenaar E.J. 
Published: November 2012

Abstract
This article examines the current and prospective roles of the Arctic Council System (ACS) within the context of the (international) law of the sea. Its first part focuses on the role of regional cooperation under the law of sea, with special attention to the way in which the pacta tertiis principle has shaped some regional regimes. The second part examines current features of the Arctic Council, including its mandate and main approaches, participation and institutional structure. The new concept of the ACS is offered to clarify the connection between the Arctic Council and the 2011 Agreement on Cooperation in Aeronautical and Maritime Search and Rescue in the Arctic and future legally binding instruments negotiated under the Council’s auspices, but not adopted by it. The article concludes with a synthesis of the current and prospective roles of the ACS under the law of the sea.