bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of crural release and ischial osteotomy for relief of tension in the repair of large segmental urethral defects in male cats
Authors: Zemer Orly , Benzioni Hadas , Kaplan Rotem , Zineman Shelly , Kelmer Efrat , Shipov Anna , Milgram Joshua 
Published: October 2013

AbstractObjectiveTo examine if the tension at the site of a urethral anastomosis can be relieved by performing either a crural release technique or an ischial osteotomy technique.Study DesignCadaveric study and 2 case reports.AnimalsAdult male cat cadavers (n = 18).MethodsCats were divided into 2 groups; crural release (n = 9) and ischial osteotomy (n = 9). In each group, 20%, 25%, and 30% of the pelvic urethra was excised in 3 cats. The length of the urethral defect was measured after excision of the urethral segment, and after approximation, before and subsequent to the tension relieving technique performed. Two clinical cases are described.ResultsBoth crural release and ischial osteotomy were effective in relieving the tension encountered at the urethral anastomosis after removal of 20% of the urethral length. In the ischial osteotomy group, apposition without tension after removing up to 30% of the intrapelvic urethral length was easily achieved. A similar technique was successfully used in 2 clinical cases.ConclusionCrural release and ischial osteotomy techniques allow approximation and tension free anastomosis of large segmental defects of the pelvic urethra in cats.
The richness and abundance of epigaeic mountain beetles in north‐western Patagonia, Argentina: assessment of patterns and environmental correlates
Authors: Werenkraut Victoria , Ruggiero Adriana 
Published: October 2013

AbstractAimOur aims were: (1) to study the shape of the species richness–elevation and abundance–elevation relationships (SRERandAER, respectively) in epigaeic mountain beetles; and (2) to analyse how richness and abundance of the beetles vary across the full gradient and within the forests and steppes in association with environmental variables representing productivity, thermal limitation, water–energy dynamics, environmental heterogeneity and soil characteristics.LocationFive mountains at temperate latitudes in north‐western Patagonia, Argentina.MethodsWe collected beetles using 486 pitfall traps arranged in fifty‐four 100 m² grid plots of nine traps, established at intervals of about 100 m of elevation from the base to the summit of each mountain. We used multi‐model selection and the Akaike information criterion to find the best ecological explanation for species richness and abundance variation.ResultsTheAERwas hump‐shaped in four mountains and negative in one;the SRERwas negative in one case, humped in two cases, and either low‐plateau or humped in the remaining two. Across the full gradient, the increase in vegetation cover, mainly associated with the presence of forests, predominately accounted forSRERs andAERs. In the forests, energy variables combined with precipitation, soil attributes and environmental heterogeneity accounted for richness and abundance. In the steppes, potential evapotranspiration and plant productivity were important.Main conclusionsWe confirmed different forms in the shape ofSRERs, and the predominance of hump‐shaped patterns inAERs. Vegetation type (forests versus steppes) accounted for most of the variation in species richness and abundance on all mountains. Associations with local environmental factors were rather more variable and changed with the spatial extent of analysis, thus confirming the spatial dependence of the species richness/abundance–environment relationships.
Children of Parents With Chronic Noncancer Pain: A Comprehensive Review of the Literature
Authors: Umberger Wendy 
Published: October 2013

TopicChronic noncancer pain (CNCP) is a prevalent occurrence and is experienced by adults in their child‐rearing years. Somatic or psychiatric illness in a parent constitutes a potential threat to the physical, mental health, and normative development in children.PurposeA comprehensive review of the literature was performed to answer the question: What are the effects of parental CNCP on children in the family system?Sources UsedThe search was performed using the Cumulative Index to Nursing and Allied Health Literature, Medline, PsycINFO, and Academic Search Premier. Search terms used were “parent pain or parent chronic pain or parent illness or parent chronic illness” and “child or adolescent or teenager.” Inclusion and exclusion criteria were developed a priori. Eighteen articles (n = 18) met criteria and were included in the sample.ConclusionsThree clusters were identified: (a) child/adolescent somatic complaints or behavior; (b) child/adolescent internalizing or externalizing symptoms; and (c) important mediating and moderating variables. The results of this review show that children and adolescents whose parents suffer from CNCP are at risk for more and similar‐to‐parent pain complaints and greater degree of internalizing and externalizing symptoms than those with healthy parents. Implications for clinical nursing practice and research are given.
Total Atrial Conduction Time Assessed by Tissue Doppler Imaging (PA‐TDI Interval) to Predict Early Recurrence of Persistent Atrial Fibrillation After Successful Electrical Cardioversion
Authors: MÜLLER PATRICK , SCHIEDAT FABIAN , BIALEK ANNA , BÖSCHE LEIF , EWERS AYDAN , KARA KAFFER , DIETRICH JOHANNES W. , MÜGGE ANDREAS , DENEKE THOMAS 
Published: October 2013

TACT Assessed by PA‐TDI IntervalBackgroundThe aim of this study was to investigate whether total atrial conduction time (TACT) assessed via tissue Doppler imaging (PA‐TDI interval) can identify patients with early recurrent atrial fibrillation (ERAF) after successful direct‐current electrical cardioversion (CV) of persistent atrial fibrillation (persPAF).Methods and ResultsA total of 54 patients without antiarrhythmic drug medication (mean ± SD: 66 ± 10.4 years; 33% women) with persPAF and successful CV were enrolled between May 2012 and May 2013.TACT was measured 6 hours after successful CV in the left atrium by tissue Doppler imaging (PA‐TDI interval). ERAF was determined via Holter‐electrocardiogram over a period of 7 days after CV. Receiver opearting characteristic analysis was used to determine an optimal cutoff value of PA‐TDI interval for prognosis of ERAF. Based on this result, recurrence‐free survival was assessed with Mantel–Haenszel's log‐rank test. ERAF occurred in 23 patients (43%). PA‐TDI interval was longer in patients with ERAF compared to those who maintained sinus rhythm (mean ± SD: 163.5 ± 11.1 vs 132.3 ± 11.2 milliseconds; P < 0.00001). At the cutoff value of 152 milliseconds, PA‐TDI interval sensitivity and specificity related to ERAF were 87% and 100%, respectively.ConclusionMeasuring PA‐TDI interval may help to predict ERAF after successful CV in patients with persAF.
Clinical Relevance of Routinely Measured Vital Signs in Hospitalized Patients: A Systematic Review
Authors: Storm‐Versloot Marja N. , Verweij Lotte , Lucas Cees , Ludikhuize Jeroen , Goslings J. Carel , Legemate Dink A. , Vermeulen Hester 
Published: October 2013

AbstractBackgroundConflicting evidence exists on the effectiveness of routinely measured vital signs on the early detection of increased probability of adverse events.PurposeTo assess the clinical relevance of routinely measured vital signs in medically and surgically hospitalized patients through a systematic review.Data SourcesMEDLINE, Embase, Cochrane Central Register of Controlled Trials (CENTRAL), Cumulative Index to Nursing and Allied Health Literature, and Meta‐analysen van diagnostisch onderzoek (in Dutch; MEDION) were searched to January 2013.Study SelectionProspective studies evaluating routine vital sign measurements of hospitalized patients, in relation to mortality, septic or circulatory shock, intensive care unit admission, bleeding, reoperation, or infection.Data ExtractionTwo reviewers independently assessed potential bias and extracted data to calculate likelihood ratios (LRs) and predictive values.Data SynthesisFifteen studies were performed in medical (n = 7), surgical (n = 4), or combined patient populations (n = 4; totaling 42,565 participants). Only three studies were relatively free from potential bias. For temperature, the positive LR (LR+) ranged from 0 to 9.88 (median 1.78; n = 9 studies); heart rate 0.82 to 6.79 (median 1.51; n = 5 studies); blood pressure 0.72 to 4.7 (median 2.97; n = 4 studies); oxygen saturation 0.65 to 6.35 (median 1.74; n = 2 studies); and respiratory rate 1.27 to 1.89 (n = 3 studies). Overall, three studies reported area under the Receiver Operator Characteristic (ROC) curve (AUC) data, ranging from 0.59 to 0.76. Two studies reported on combined vital signs, in which one study found an LR+ of 47.0, but in the other the AUC was not influenced.ConclusionsSome discriminative LR+ were found, suggesting the clinical relevance of routine vital sign measurements. However, the subject is poorly studied, and many studies have methodological flaws. Further rigorous research is needed specifically intended to investigate the clinical relevance of routinely measured vital signs.Clinical RelevanceThe results of this research are important for clinical nurses to underpin daily routine practices and clinical decision making.
Relational regulation theory and the role of social support and organisational fairness for nurses in a general acute context
Authors: Rodwell John , Munro Louise 
Published: October 2013

Aims and objectivesTo present a novel approach to nurse stress by exploring the demand–control–support model with organisational justice through the lens of relational regulation theory.BackgroundNursing is often stressful due to high demands and dissatisfaction with pay, which impacts the mental well‐being and productivity of nurses.DesignA cross‐sectional design.MethodsA validated questionnaire was sent to the work addresses of all nursing and midwifery staff in a medium‐sized general acute hospital in Australia. A total of 190 nurses and midwives returned completed questionnaires for the analyses.ResultsThe multiple regression analyses demonstrated that the model applies to the prototypical context of a general acute hospital and that job control, supervisor support and outside work support improve the job satisfaction and mental health of nurses.ConclusionsMost importantly, supervisor support was found to buffer the impact of excessive work demands. Fairness of procedures, distribution of resources and the quality and consistency of information are also beneficial. Relational regulation theory is applied to these findings as a novel way to conceptualise the mechanisms of support and fairness in nursing.Relevance to clinical practiceThe importance of nurses' well‐being and job satisfaction is a priority for improving clinical outcomes. Practically, this means nurse managers should be encouraging nurses in the pursuit of diverse relational activities both at work and outside work.
Lack of association between LIPC‐514 C/T polymorphism of hepatic lipase and endometriosis in Iranian women
Authors: Sahmani Mehdi , Ghaleh Talaat Dabbaghi , Darabi Maryam , Darabi Masoud , Rashvand Zahra , Najafipour Reza 
Published: October 2013

AbstractAimPatients with endometriosis may suffer from dyslipidemia. Hepatic lipase (HL) is involved in the metabolism of lipoproteins and has an important role in reverse cholesterol transport. The aim of this study was to investigate the association between the LIPC‐514 C/T polymorphism in the HL gene and the risk of endometriosis in a group of Iranian women.MethodsNinety‐seven patients with endometriosis and 107 women who were negative for endometriosis after diagnostic laparoscopy, as control group, were enrolled in this cross‐sectional study. Samples were analyzed for polymorphism of the HL gene using polymerase chain reaction restriction fragment length polymorphism.ResultsMultivariate analysis was used to examine the association between the risk of endometriosis and LIPC‐514 C/T polymorphism. There was no statistically significant difference in the frequency of the LIPC‐514 C/T polymorphism between patients and the controls (60.7% CC, 34.6% CT, 4.7% TT versus 68.4%, 27.4%, 4.2%, respectively, P = 0.52).ConclusionThe present study suggested that the LIPC‐514 C/T polymorphism of the HL gene has no significant association with the risk of endometriosis in the studied Iranian women.
High‐risk human papilloma virus management in pregnancy with cervical intraepithelial neoplasia during pregnancy and postpartum in China
Authors: He Yue , Wu Yu‐Mei , Zhao Qun , Wang Tong , Song Fang , Zhu Li 
Published: October 2013

AbstractAim To investigate the relationship between cervical intraepithelial neoplasia (CIN) and high‐risk human papilloma virus (HR‐HPV) during pregnancy and postpartum in China.MethodsIn this prospective case–control study, 168 pregnant women with CIN and cervicitis were diagnosed by colposcopic cervical biopsy. All the cases underwent hybrid capture assay version II (HCII) to detect HR‐HPV DNA load amounts and the tests were completed in 3–6 months after childbirth.ResultsDuring pregnancy: as the CIN grade increased, the HR‐HPV infection rates increased (P = 0.002), but HR‐HPV DNA load amounts (in logarithms) did not change obviously (P = 0.719). 3–6 months postpartum: as the CIN grade increased, the natural negative rate of HR‐HPV decreased (P = 0.000), while the amount of HR‐HPV DNA (in logarithms) increased (P = 0.036); especially the amount of HR‐HPV DNA in pregnant women with CINIII was significantly higher than that of other grades. During pregnancy and 3–6 months postpartum : the amount of HR‐HPV DNA (in logarithms) during pregnancy was higher than that of 3–6 months postpartum with the same grade of CIN.ConclusionThe findings emphasize the importance of undergoing the HCII test 3–6 months postpartum. It should be noted that HR‐HPV may turn negative in pregnancy with CINIII 3–6 months after childbirth. Further treatments of pregnancy with CIN should be considered according to the CIN grade diagnosed by cervical biopsy via colposcopy 3–6 months after birth, but not according to the persistence of HR‐HPV during pregnancy.
High‐risk human papillomavirus correlates with recurrence after laser ablation for treatment of patients with cervical intraepithelial neoplasia 3: A long‐term follow‐up retrospective study
Authors: Inaba Kanako , Nagasaka Kazunori , Kawana Kei , Arimoto Takahide , Matsumoto Yoko , Tsuruga Tetsushi , Mori‐Uchino Mayuyo , Miura Shiho , Sone Kenbun , Oda Katsutoshi , Nakagawa Shunsuke , Yano Tetsu , Kozuma Shiro , Fujii Tomoyuki 
Published: October 2013

AbstractAimThe purpose of our study was to evaluate the efficacy of laser ablation as a conservative treatment for cervical intraepithelial neoplasia 3 (CIN3) and assess whether the human papillomavirus (HPV) test is useful to predict recurrence after treatment.Materials and MethodsA total of 134 patients who received laser ablation for treatment of CIN3 were enrolled in this study. During the follow‐up period, patients were followed with cytological and colposcopic evaluations. Recurrence of CIN3 was regarded as the primary end‐point. HPV genotype was tested before and after treatment. Post‐treatment cumulative recurrence rates were estimated and comparisons by both patient age and HPV genotype were performed.ResultsOverall cumulative recurrence rate of CIN3 in the first year after treatment was 22.6% for all patients. No significant correlation was shown between patient age and recurrence. Patients infected by specific genotypes (16, 18, 31, 33, 52, and 58) frequently failed to clear the infection after treatment. The 1‐year recurrence‐free survival in those positive after treatment for eight high‐risk genotypes (16, 18, 31, 33, 35, 45, 52, and 58) was significantly lower (66.7%), compared to that in those positive for other high‐risk types (78.6%). The recurrence‐free survival of those who remained HPV‐positive after treatment was significantly lower than those who turned negative.ConclusionLaser ablation should be performed prudently with appropriate patient counseling about recurrence rate. Considering its minimal invasiveness, laser ablation is effective, especially for young patients who are negative for eight high‐risk genotypes. With regard to HPV testing, although genotyping has significant value for predicting recurrence, screening for all genotypes warrants further evaluation.
Increased proatherogenic monocyte–platelet cross‐talk in monocyte subpopulations of patients with stable coronary artery disease
Authors: Czepluch F. S. , Kuschicke H. , Dellas C. , Riggert J. , Hasenfuss G. , Schäfer K. 
Published: October 2013

AbstractBackgroundMonocytes and platelets are important cellular mediators of atherosclerosis. Human monocytes can be divided into CD14++CD16−, CD14++CD16+ and CD14+CD16++ cells, which differ in their functional properties. The aim of this study was to examine monocyte subset distribution, monocyte–platelet aggregate (MPA) formation and expression of CCR5, the receptor of the platelet‐derived chemokine CCL5, and to determine whether these parameters are altered in individuals with coronary atherosclerosis.MethodsPeripheral blood cells from 64 healthy blood donors (HBDs) and 60 patients with stable coronary artery disease (CAD) were stained with antibodies against CD14, CD16, CD42b and CCR5 and analysed by flow cytometry. Circulating CCL5 levels were determined using an enzyme‐linked immunosorbent assay.ResultsIn patients with CAD, the relative proportion of the CD14++CD16− monocyte subset was elevated (P < 0.05) and of the CD14+CD16++ subset was reduced (P < 0.001) compared with the HBD group. Furthermore, MPA formation significantly increased in patients with CAD in all three monocyte subsets. In both study groups, the majority of CCR5+ cells was detected in CD14++CD16+ monocytes (P < 0.001 versus CD14++CD16− and CD14+CD16++), although the CCR5+ monocyte number was reduced in patients with CAD (CD14++CD16−/CD14+CD16++, P < 0.001; CD14++CD16+, P < 0.05) compared with the HBD group, particularly in those who were not taking statins. Ex vivo incubation of monocytes from HBDs with plasma from patients with CAD also decreased CCR5+ expression (P < 0.05 versus plasma from HBDs). Serum CCL5 levels were similar in both groups.ConclusionsThe increased monocyte–platelet cross‐talk in patients with CAD might have contributed to atherosclerosis progression. The decreased CCR5+ monocyte numbers in patients with CAD could have resulted from CCR5+ cell recruitment into atherosclerotic lesions or CCR5 downregulation in response to circulating factors.
Influence of age, disease onset and ApoE4 on visual medial temporal lobe atrophy cut‐offs
Authors: Pereira J. B. , Cavallin L. , Spulber G. , Aguilar C. , Mecocci P. , Vellas B. , Tsolaki M. , Kłoszewska I. , Soininen H. , Spenger C. , Aarsland D. , Lovestone S. , Simmons A. , Wahlund L.‐O. , Westman E. ,   AddNeuroMed consortium and for the Alzheimer's Disease Neuroimaging Initiative
Published: October 2013

AbstractBackgroundVisual assessment of medial temporal lobe atrophy (MTA; range 0–4, from no atrophy to increasing atrophy of the choroid fissure, temporal horns and hippocampus) is a sensitive radiological marker of Alzheimer's disease (AD). One of the critical elements for visual MTA assessment is the cut‐off score that determines deviation from normality.MethodsIn this study, we assessed the sensitivity and specificity of different MTA cut‐off scores to classify control subjects, individuals with mild cognitive impairment (MCI) and AD patients from two large independent cohorts, AddNeuroMed and Alzheimer's Disease Neuroimaging Initiative. Of note, we evaluated the effects of clinical, demographic and genetic variables on the classification performance according to the different cut‐offs.ResultsA cut‐off of ≥1.5 based on the mean MTA scores of both hemispheres showed higher sensitivity in classifying patients with AD (84.5%) and MCI subjects (75.8%) who converted to dementia compared to an age‐dependent cut‐off. The age‐dependent cut‐off showed higher specificity or ability to correctly identify control subjects (83.2%) and those with MCI who remained stable (65.5%). Increasing age, early‐onset disease and absence of the ApoE ε4 allele had a stronger influence on classifications using the ≥1.5 cut‐off. Above 75 years of age, an alternative cut‐off of ≥2.0 should be applied to achieve a classification accuracy for both patients with AD and control subjects that is clinically useful.ConclusionClinical, demographic and genetic variables can influence the classification of MTA cut‐off scores, leading to misdiagnosis in some cases. These variables, in addition to the differential sensitivity and specificity of each cut‐off, should be carefully considered when performing visual MTA assessment.
WHERE IS AN OIL SHOCK?
Authors: Engemann Kristie M. , Owyang Michael T. , Wall Howard J. 
Published: October 2013

ABSTRACTMuch of the literature examining the effects of oil shocks asks the question “What is an oil shock?” and has concluded that oil‐price increases are asymmetric in their effects on the U.S. economy. That is, sharp increases in oil prices affect economic activity adversely, but sharp decreases in oil prices have no effect. We reconsider the directional symmetry of oil‐price shocks by addressing the question “Where is an oil shock?” the answer to which reveals a great deal of spatial/directional asymmetry across states. Although most states have typical responses to oil‐price shocks—they are affected by positive shocks only—the rest experience either negative shocks only (five states), both positive and negative shocks (five states), or neither shock (five states).
Thoracoscopic pericardial window for management of pericardial effusion in 15 dogs
Authors: Atencia S. , Doyle R. S. , Whitley N. T. 
Published: October 2013

ObjectivesTo report short‐term complications and long‐term outcomes of thoracoscopic pericardial window for management of pericardial effusion in dogs.MethodsRetrospective study of dogs in which thoracoscopic pericardial window was performed using a three‐cannula technique. Surgery time, complications, postoperative management, area of resected pericardium, histopathology results and outcome were evaluated.ResultsDiagnoses included dogs with idiopathic pericardial effusion (n = 10), cardiac mass (n = 4) and mesothelioma (n = 1). One case required conversion to sternotomy. Median thoracoscopic surgery time was 52 · 5 (range, 45‐80) minutes. Complications occurred in four (26%) cases. Median time to discharge was one (range, 1‐6) day. Of dogs with idiopathic pericardial effusion, one is alive at 150 days, one was lost to follow‐up at 180 days while eight were euthanased of which five were for unrelated reasons. All dogs with neoplastic causes died or were euthanased because of their illness. Median survival time for dogs with idiopathic pericardial effusion (635 days; range, 70‐1165) was significantly longer than that for dogs with neoplasia (30 days; range, 1‐107).Clinical SignificanceThoracoscopic pericardial window is of low morbidity with short surgery and hospitalisation times. It provides good long‐term control of idiopathic pericardial effusion but short‐term palliation of clinical signs in dogs with neoplastic disease.
European fossil fruits ofSphenothecarelated to extant Asian species ofSymplocos
Authors: MANCHESTER Steven R. , FRITSCH Peter W. 
Published: October 2013

AbstractWe are compelled to sink the European fossil fruit genusSphenothecaKirchheimer into extantSymplocosbased on newly recognized morphological and anatomical similarity with the fruits of extantSymplocos tanakaeMatsum. of Japan andSymplocos henryiBrand of SW China. Recognition ofSymplocos incurva(Kirchheimer) comb. nov. andSymplocos bornensis(Mai) comb. nov. increases the number of late Paleogene and Neogene European species ofSymplocosto 13. The close relationship between this fossil species and extant species of theSymplocos lucidaclade of eastern Asia suggests that migration of this group between Europe and Asia was facilitated by the closure of the Turgai Strait that commenced during the Oligocene.