bluuebunny/crossref_metadata_2025_split huggingface dataset:
Escuchando las mujeres: cooperativas y asociaciones sociales y solidarias como red de apoyo, un ejemplo brasileño
Authors: Gutierrez Ruiz Julia da Silva , Pereira Morais Leandro 
Published: July 2024

En Brasil, muchas mujeres son víctimas de distintas formas de violencia doméstica, que puede ser física, psicológica, moral, sexual y patrimonial. Las mujeres víctimas de violencia doméstica tienden a buscar personas cercanas para pedir ayuda para salir de la situación, por lo tanto, una red de apoyo informal puede ser una herramienta importante para que las mujeres se sientan protegidas y pidan ayuda a las organizaciones públicas. Dado que las empresas económicas solidarias (EES) formadas solamente por mujeres son un espacio para que las mujeres se fortalezcan mutuamente, donde socializan y pueden crear vínculos, también pueden servir como red de apoyo informal para las mujeres que las forman, además de fomentar su autonomía financiera. El objetivo de este artículo es identificar si las EES pueden formar parte de una red de apoyo a las mujeres, desde la perspectiva de las mujeres que las forman. Para ello, se investigó tres EES de mujeres en el municipio brasileño de Araraquara, que tiene una importante historia de movimientos sociales y políticas públicas dirigidas a la economía social y solidaria. A partir de las entrevistas semiestructuradas realizadas a 11 mujeres de tres de estos EES, fue posible obtener resultados que explican lo que ocurre en el campo empírico en relación con la teoría, como que las mujeres se sienten cómodas y confían unas en otras, pero al mismo tiempo no identifican la violencia patrimonial como violencia.
The right to work-life balance in Portuguese cooperatives. A legal and empirical analysis
Authors: Meira Deolinda , Castro Conceição , Antunes Sofia 
Published: July 2024

This paper aims to assess whether cooperatives are the ideal setting for promoting the work-life balance, a right whose protection has been built in close connection with the promotion of gender equality. To this end, we intend to answer the following questions: (i) What are the main dimensions of the right to work-life balance, and what is the relevance of protecting this right to promote gender equality? (ii) To what extent can the legal regime of cooperatives promote the right to work-life balance and, consequently, gender equality? (iii) What are the main facilitators and obstacles to work-life balance in cooperatives from the perspective of women and men?From a methodological point of view, our study is based on a review of the literature, legislation, and an empirical study. The empirical analysis was based on the results of a questionnaire survey, which yielded 414 valid responses from employees of SEEs, including 62 from cooperatives. The statistical methods followed were descriptive statistics, non-parametric tests and post-hoc tests. The findings shed light on the specific challenges faced by employees in cooperatives regarding work-life balance and highlight the importance of open and supportivecommunication channels within the workplace and flexibility in time management. The results also suggest that cooperatives, according to the perception of employees, are the ones that promote more facilitators and that their organisational culture and climate are favourable to fostering a healthy work-life balance. The observed outcomes can be primarily attributed to the democratic and participatory management inherent in cooperative structures.
The prognostic role of lymphocyte-to-monocyte ratio in patients with resectable pancreatic cancer: a systematic review and meta-analysis
Authors: Li Haipeng , Peng Shang , An Ran , Du Nana , Wu Huan , Zhen Xiangcheng , Gao Yuanzhi , Li Zhenghong , Min Jingting 
Published: July 2024

Objectives
This systematic review and meta-analysis examined whether the lymphocyte-to-monocyte ratio (LMR) can serve as an indicator for predicting the prognosis of patients with resectable pancreatic cancer.

Patients and Methods
This meta-analysis was registered with PROSPERO: CRD42023461260. A systematic literature search was conducted in the PubMed, Embase, Cochrane, and Web of Science databases up to September 2023 to assess whether LMR can predict the prognosis of patients with resectable pancreatic cancer. The outcomes measured included subgroup analyses of overall survival (OS) with hazard ratios (HR) and confidence intervals of geographical region, patient population, and LMR threshold. A sensitivity analysis was also performed for OS and HR and confidence intervals were calculated for recurrence-free survival (RFS).

Results
A total of 14 eligible articles, comprising 4,019 patients, were included in the comprehensive analysis. The results of this comprehensive analysis indicate that LMR is a robust predictor of OS, demonstrating strong prognostic significance (HR = 0.55, 95% CI [0.44–0.69], I2 = 79%, P < 0.00001). This predictive significance extended to various types of pancreatic cancer, such as pancreatic ductal adenocarcinoma (HR = 0.73, 95% CI [0.57–0.93], I2 = 46%, P = 0.01), pancreatic neuroendocrine neoplasms (HR = 0.81, 95% CI [0.66–0.99], P = 0.04) and other subtypes (HR = 0.40, 95% CI [0.22–0.72], I2 = 89%, P < 0.00001), but not to pancreatic head cancer (HR = 0.46, 95% CI [0.16–1.13], I2 = 59%, P = 0.12). LMR retained its predictive value across different regions, including Asia (HR = 0.62, 95% CI [0.47–0.76], I2 = 68%, P < 0.0001), Europe (HR = 0.78, 95% CI [0.67–0.91], I2 = 0%, P = 0.002), and the Americas (HR = 0.14, 95% CI [0.08–0.24], I2 = 0%, P < 0.00001). Notably, both LMR cut-off values greater than or equal to three (HR = 0.62, 95% CI [0.47–0.82], I2 = 67%, P = 0.0009) and less than three (HR = 0.47, 95% CI [0.32–0.69], I2 = 85%, P = 0.0001) exhibited prognostic significance. The sensitivity analysis for OS confirmed the strong predictive value of LMR, whereas LMR did not exhibit predictive significance for RFS (HR = 0.35, 95% CI [0.09–1.32], I2 = 95%, P = 0.12). In both subgroups categorized by Newcastle-Ottawa Scale (NOS) scores of ≥7 (HR = 0.66, 95% CI [0.54–0.80], I2 = 53%, P = 0.04) and <7 (HR = 0.41, CI [0.23–0.72], I2 = 89%, P < 0.00001), LMR was demonstrated to have predictive value.

Conclusion
Despite the observed heterogeneity and potential biases in the included studies, the findings of this study suggest that LMR may serve as a valuable predictor of OS in patients with resectable pancreatic cancer.
Treatment gap and barriers to access mental healthcare among women with postpartum depression symptoms in Pakistan
Authors: Sajjad Aqsa , Shah Shahid , Abbas Ghulam , Aslam Ayesha , Randhawa Fawad , Khurram Haris , Assiri Abdullah 
Published: July 2024

Background and Objectives
Postpartum depression (PPD) is prevalent among women after childbirth, but accessing mental healthcare for PPD is challenging. This study aimed to assess the treatment gap and barriers to mental healthcare access for women with PPD symptoms living in Punjab, Pakistan.

Methods
A multicenter cross-sectional study was conducted in five populous cities of Punjab from January to June 2023 by administering the questionnaire to the women using stratified random sampling. A total of 3,220 women in first 6 months postpartum were screened using the Edinburgh Postnatal Depression Scale. Of them, 1,503 women scored thirteen or above, indicating potential depressive disorder. Interviews were conducted to explore help-seeking behavior and barriers to accessing mental healthcare. Descriptive statistics along with nonparametric tests (e.g., Kruskal–Wallis, Mann–Whitney U) were used and group differences were examined. Scatter plot matrices with fitted lines were used to explore associations between variables. Classification and regression tree methods were used to classify the importance and contribution of different variables for the intensity of PPD.

Results
Only 2% of women (n = 33) with high PPD symptoms sought mental healthcare, and merely 5% of women (n = 75) had been in contact with a health service since the onset of their symptoms. 92.80% of women with PPD symptoms did not seek any medical attention. The majority of women, 1,215 (81%), perceived the need for mental health treatment; however, 91.23% of them did not seek treatment from healthcare services. Women who recently gave birth to a female child had higher mean depression scores compared to those who gave birth to a male child. Age, education, and birth location of newborn were significantly associated (p < 0.005) with mean barrier scores, mean social support scores, mean depression scores and treatment gap. The results of classification and regression decision tree model showed that instrumental barrier scores are the most important in predicting mean PPD scores.

Conclusion
Women with PPD symptoms encountered considerable treatment gap and barriers to access mental health care. Integration of mental health services into obstetric care as well as PPD screening in public and private hospitals of Punjab, Pakistan is critically needed to overcome the treatment gap and barriers.
Flowering-associated gene expression and metabolic characteristics in adzuki bean (Vigna angularis L.) with different short-day induction periods
Authors: Dong Weixin , Li Dongxiao , Zhang Lei , Tao Peijun , Zhang Yuechen 
Published: July 2024

Background
The adzuki bean is a typical short-day plant and an important grain crop that is widely used due to its high nutritional and medicinal value. The adzuki bean flowering time is affected by multiple environmental factors, particularly the photoperiod. Adjusting the day length can induce flower synchronization in adzuki bean and accelerate the breeding process. In this study, we used RNA sequencing analysis to determine the effects of different day lengths on gene expression and metabolic characteristics related to adzuki bean flowering time.

Methods
‘Tangshan hong xiao dou’ was used as the experimental material in this study and field experiments were conducted in 2022 using a randomized block design with three treatments: short-day induction periods of 5 d (SD-5d), 10 d (SD-10d), and 15 d (SD-15d).

Results
A total of 5,939 differentially expressed genes (DEGs) were identified, of which 38.09% were up-regulated and 23.81% were down-regulated. Gene ontology enrichment analysis was performed on the target genes to identify common functions related to photosystems I and II. Kyoto Encyclopedia of Genes and Genomes enrichment analysis identified two pathways involved in the antenna protein and circadian rhythm. Furthermore, florescence was promoted by down-regulating genes in the circadian rhythm pathway through the blue light metabolic pathway; whereas, antenna proteins promoted flowering by enhancing the reception of light signals and accelerating electron transport. In these two metabolic pathways, the number of DEGs was the greatest between the SD-5d VS SD-15d groups. Real-time reverse transcription‒quantitative polymerase chain reaction analysis results of eight DEGs were consistent with the sequencing results. Thus, the sequencing results were accurate and reliable and eight genes were identified as candidates for the regulation of short-day induction at the adzuki bean seedling stage.

Conclusions
Short-day induction was able to down-regulate the expression of genes related to flowering according to the circadian rhythm and up-regulate the expression of certain genes in the antenna protein pathway. The results provide a theoretical reference for the molecular mechanism of short-day induction and multi-level information for future functional studies to verify the key genes regulating adzuki bean flowering.
Assessment of Antimicrobial Activities of Some Selected Medicinal Plants Used in the Treatment of Skin and Wound Infections in Bauchi Town, Bauchi State Nigeria
Authors: S.B Zailani , Y. U. Shuiabu , M.B. Adamu , Q. Mudathir, , N.D. Zakari , A.S Lawal , L. Muhammad 
Published: July 2024

Aims: This study aimed to capture the medicinal plants used locally to treat skin and wound infection, and to investigate the antimicrobial activity of the ethanol, ethyl acetate, and aqueous extracts of Azadiracta indica, Mitracarpus hirtus, Calotropis procera, and Commiphora africana against bacterial and fungal pathogens causing skin and wound infections.
Study Design: This was a cross-sectional analytical study, conducted in Bauchi town from January to April 2024 at the Department of Medical Microbiology, Abubakar Tafawa Balewa University.
Methodology: A semi-structured questionnaire was used to gather information on the use of medicinal plants in treating skin and wound diseases. Twelve leaves extracts from Azadirachta indica, Mitracarpus hirtus, Calotropis procera, and Commiphora africana were screened for their antimicrobial activity against four bacterial and one fungal pathogen; Staphylococcus aureus, Proteus mirabilis, Pseudomonas aeruginosa klebsiella pneumonia, Escherichia coli and Trichophyton rubrum using Agar Disc Diffusion Assay. Minimum Inhibitory Concentrations (MIC) was performed using micro broth dilution assay.
Results: A total of 94 respondents used 28 medicinal plants for skin and wound disease management, including leaf paste, infusion, root powder, dried powdered leaves, and oral decoction. The most common plants used were Azadirachta indica, Mitracarpus hirtus, Calotropis procera, and Commiphora africana, used to treat eczema, ringworm, skin rashes, and burnt wounds. All of the plant extracts were effective in inhibiting bacterial and fungal growth at variable concentrations, with Mitracarpus hirtus being the most effective. Mitracarpus hirtus showed the greatest zone of inhibition (ZOI >20 mm) against Staphyloccus aureus and Trichophyton rubrum, followed by Calotropis procera, which had moderate activity on the test isolates with a mean ZOI >11mm. Azadirachta indica and Commiphora africana exhibited mild to poor action on the majority of the isolates. For each plant extract, the MIC values differed according to the bacterial species. Mitracarpus hirtus had the lowest MIC against Staphyloccus aureus at 0.325 mg/mL, as did Calotropis procera against Klebsiella pneumoniae.
Conclusion: The study discovered that many medicinal plants had promising antibacterial activities against the tested isolates, but more research is required to identify and purify active components for safe use.
Profile of Primary Headache Patients at Tanjung Priok Health Center for the Period of January – December 2023
Authors: Yudawijaya Agus , Londo Auxilia Briliana Shirley , Wibhawa Patria Adri , Pariama Ganda , Aritonang Christina Roseville Lasma 
Published: July 2024

Aims: To find out the profile of primary headache patients at the Tanjung Priok Community Health Center from January 2023 to December 2023.
Study Design: This research is a type of descriptive research with a cross-sectional research design. Data was obtained through secondary data collection, namely medical record data at the Tanjung Priok Community Health Center from January to December 2023.
Place and Duration of Study: This research was conducted at the Tanjung Priok Community Health Center in January 2024.
Methodology: The population of this study were all patients with a primary working diagnosis of primary headache disease at the Tanjung Priok Community Health Center for the period January 2023 – December 2023. Primary headache patients at the Tanjung Priok Community Health Center were declared to have met the inclusion and exclusion criteria. The sampling technique that will be used is the Total Sampling technique, namely the number of samples is the same as the number of medical records that will be used in the research.
Results: The results obtained from this study were that of the 125 patients diagnosed with primary headache, the most patients experienced tension-type headache, namely 93 patients (74.4%), and migraine with aura was the least experienced, namely 4 patients (3.2%); The gender that experienced primary headaches was women, namely 77 patients (61.6%), while men were 48 patients (38.4%); Primary headache sufferers with an age range of more than 30 years to 60 years are the age with the largest number of patients, namely 64 patients (51.2%), while those aged more than 60 years experience the least number of primary headaches, namely 6 patients (4.8%); Based on employment, the largest group of patients who did not work was 79 patients (63.2%); Based on the choice of therapy, the majority of primary headache patients were treated medically, namely 113 patients (90.4%).
Conclusion: That still are many patients who experienced primary headaches at the Tanjung Priok Community Health Center for the period January 2023 to December 2023, including female patients with an age range of 30-60 years and unemployed. This is of course important for all stakeholders to pay attention to to develop appropriate service programs as an effort to prevent and treat primary headaches, which even though they are categorized as mild illnesses, can have an impact on various things, including a person's daily performance in activities.
Pediatric glaucoma terminology
Authors: Ganesh Anuradha , Mai Dang Tam , Levin Alex V. 
Published: October 2013

AbstractGlaucoma is a term that refers to many different disorders which may be characterized by age of onset, associated ocular findings, or associated systemic malformations and diseases. Specification of the type of glaucoma, both clinically, and where applicable, molecularly aids in diagnosis, counseling, treatment, and prognosis. The objective of this report is to assist geneticists in understanding glaucoma and recognizing the importance of detailed terminology in clinical genetic diagnosis. © 2013 Wiley Periodicals, Inc.
Direct Aldol Polymerization of Acetaldehyde with Organocatalyst/Brønsted Acid Systems
Authors: Kusumoto Shuhei , Ito Shingo , Nozaki Kyoko 
Published: October 2013

AbstractThe direct aldol polymerization of acetaldehyde, a new approach for the synthesis of poly(vinyl alcohol)‐ and poly(vinyl alcohol‐co‐ethylene)‐type oligomers, cooperatively catalyzed by organocatalysts and Brønsted acids was investigated. Thus, we successfully obtained oligomers that contain a substantial amount of 1,3‐hydroxy groups in the main chain. This conceptually new approach is an important step towards realizing the one‐step synthesis of poly(vinyl alcohol)s from acetaldehyde with perfect atom economy.
Comparing options for pair housing rhesus macaques using behavioral welfare measures
Authors: Baker Kate C. , Bloomsmith Mollie A. , Oettinger Brooke , Neu Kimberly , Griffis Caroline , Schoof Valérie A. M. 
Published: October 2013

AbstractIn a biomedical research environment, research or management procedures may render continuous full contact pairing of rhesus macaques (Macaca mulatta) unfeasible. This study aimed to determine whether separation on a frequent basis or housing in adjacent cages with tactile contact interferes with the behavioral benefits of continuous full contact. Behavioral data (1260 hours) were collected from 32 adult females and 16 adult males housed at two National Primate Research Centers. Subjects were studied in four housing conditions: single housing, full contact pair housing, intermittent contact pair housing, and protected contact housing. After introduction, each pair was housed in each of the three social housing conditions in varying order. Among females, but not males, introducing animals into full and intermittent contact reduced levels of abnormal behavior. There was a trend toward this reduction in protected contact. In both females and males, full and intermittent contact was associated with lower levels of anxiety‐related behavior, but protected contact was not. Females spent more time inactive in protected contact than either full or intermittent contact, and males showed a trend toward less inactivity following introduction into full contact. Both sexes showed less affiliation in protected contact compared to the other forms of social housing. Agonistic behavior among females was not affected by housing condition; among males, levels were equivalent in full and intermittent contact but were higher in intermittent than protected contact. Frequent separation of pairs does not appear to detract from the behavioral benefits of pair housing. Separation by a barrier permitting tactile contact is inferior to other forms of social housing but showed modest improvements over single housing nonetheless. This study can guide the provision of social contact to rhesus macaques under conditions restricting pairs from continuous full contact. Am. J. Primatol. 76:30–42, 2014. © 2013 Wiley Periodicals, Inc.
Geographic origins and dietary transitions during the bronze age in the oman peninsula
Authors: Gregoricka Lesley A. 
Published: October 2013

ABSTRACTThe nature of the Bronze Age transition from the Umm an‐Nar (ca. 2700–2000 BC) to the Wadi Suq (ca. 2000–1300 BC) period in the Oman Peninsula has been highly debated by archaeologists, with some characterizing the latter as a time of cultural isolation, social collapse, and/or population replacement following the successful involvement of the area in widespread interregional exchange networks across Arabia and South Asia. The hypothesis that a substantial change in residential mobility, immigration, and diet took place in response to considerable societal changes as reflected by the archaeological record was tested using stable oxygen and carbon isotope analysis. Archaeological human dental enamel from individuals interred in six Umm an‐Nar (n = 100) and seven Wadi Suq (n = 16) communal tombs in the United Arab Emirates was used. Oxygen isotope data reveal largely homogeneous ratios indicative of a predominantly local population that acquired water from isotopically similar sources, although the presence of immigrants during both periods suggests that the region was not as isolated as previously held. Carbon isotope data exhibit a substantial temporal shift from an extremely varied to a more restricted diet, demonstrating that while considerable changes in subsistence strategies and social organization took place in the early second millennium BC, population continuity and sustained (although lessened) participation in pan‐Gulf trade systems best characterizes this regional transformation. Am J Phys Anthropol 152:353–369, 2013. © 2013 Wiley Periodicals, Inc.
COX‐2 overexpression in sinonasal inverted papilloma
Authors: Suh Jeffrey D. , Palma‐Diaz Fernando , Bhuta Sunita , Wang Marilene B. 
Published: October 2013

BackgroundInverted papilloma (IP) is a benign, but locally aggressive neoplasm of the nasal cavity and paranasal sinuses. The mainstay of treatment of IP is surgical resection, but high rates of tumor recurrence have been reported. Cyclo‐oxygenase‐2 (COX‐2) has been found to be overexpressed in many tumors and has been used successfully as a therapeutic target. The goal of this study is to highlight COX‐2 expression in IP.MethodsImmunohistochemistry for COX‐2 was performed on IP samples obtained during surgical resection between January 2012 and June 2013. The intensity of staining was evaluated by 2 head and neck pathologists blinded to the clinical features and outcomes. A positive stain was defined as having 10% or more of tumor cells exhibiting immunoreactivity.ResultsThe study includes 13 tumor samples from 7 females and 6 males. Mean age was 54.5 (range, 18–81) years. Tumor locations included: nasal septum (1), ethmoid (3), sphenoid (4), and maxillary (5) sinuses. No tumors demonstrated malignancy or dysplasia. Five (38%) of the 13 IP samples stained strongly positive for COX‐2, and 3 of 13 (23%) stained weakly positive. There were no clinical differences in patients that stained strongly or weakly for COX‐2.ConclusionCOX‐2 overexpression was identified in 62% of cases of IP in this study, and strongly positive in 38% of cases. Larger studies are necessary to identify the true incidence of COX‐2 expression for this tumor. Pharmaceuticals targeting COX‐2 may eventually provide an additional therapeutic option for select cases of recurrent or unresectable IP.