bluuebunny/crossref_metadata_2025_split huggingface dataset:
NAVIGATING IN TROUBLED WATERS: SOUTH AMERICAN EXPORTS OF FOOD AND AGRICULTURAL PRODUCTS, 1900-1950
Authors: PINILLA VICENTE , APARICIO GEMA 
Published: March 2015

ABSTRACTThe objective of this article is to offer empirical evidence regarding the behaviour of the exports and relative prices of agricultural and food products from South America between 1900 and 1950. These were years of intense turbulence, which profoundly affected the countries of the region, generating a deep pessimism concerning the potentiality of the export-led development model. This study offers a new quantitative base to analyse the evolution of exports of agrifood products from South America between 1900 and 1938. The paper also offers a series for the evolution of the terms of trade in the region which takes into account in its construction, for the first time, the relative weights of South American exports of the distinct agricultural products.
Preliminary result of rapid solenoid for controlling heavy-ion beam parameters of laser ion source
Authors: Okamura Masahiro , Sekine Megumi , Ikeda Shunsuke , Kanesue Takeshi , Kumaki Masafumi , Fuwa Yasuhiro 
Published: March 2015

AbstractTo realize a heavy-ion inertial fusion (HIF) driver, we have studied a possibility of laser ion source (LIS). A LIS can provide high-current high-brightness heavy-ion beams; however, it was difficult to manipulate the beam parameters. To overcome the issue, we employed a pulsed solenoid in the plasma drift section and investigated the effect of the solenoid field on singly charged iron beams. The rapid ramping magnetic field could enhance limited time slice of the current and simultaneously the beam emittance changed accordingly. This approach may also be useful to realize an ion source for HIF power plant.
A 3-PRS parallel manipulator for ankle rehabilitation: towards a low-cost robotic rehabilitation
Authors: Vallés Marina , Cazalilla José , Valera Ángel , Mata Vicente , Page Álvaro , Díaz-Rodríguez Miguel 
Published: March 2015

SUMMARYThis paper presents the design, kinematics, dynamics and control of a low-cost parallel rehabilitation robot developed at the Universitat Politècnica de Valencia. Several position and force controllers have been tested to ensure accurate tracking performances. An orthopedic boot, equipped with a force sensor, has been placed over the platform of the parallel robot to perform exercises for injured ankles. Passive, active-assistive and active-resistive exercises have been implemented to train dorsi/plantar flexion, inversion and eversion ankle movements. In order to implement the controllers, the component-based middleware Orocos has been used with the advantage over other solutions that the whole scheme control can be implemented modularly. These modules are independent and can be configured and reconfigured in both configuration and runtime. This means that no specific knowledge is needed by medical staff, for example, to carry out rehabilitation exercises using this low-cost parallel robot. The integration between Orocos and ROS, with a CAD model displaying the actual position of the rehabilitation robot in real time, makes it possible to develop a teleoperation application. In addition, a teleoperated rehabilitation exercise can be performed by a specialist using a Wiimote (or any other Bluetooth device).
Transnationalism, Multilingualism, and Identity
Authors: Duff Patricia A. 
Published: March 2015

ABSTRACTApplied linguistics is a field concerned with issues pertaining to language(s) and literacies in the real world and with the people who learn, speak, write, process, translate, test, teach, use, and lose them in myriad ways. It is also fundamentally concerned withtransnationalism, mobility, andmultilingualism—the movement across cultural, linguistic, and (often) geopolitical or regional borders and boundaries. The field is, furthermore, increasingly concerned withidentityconstruction and expression through particular language and literacy practices across the life span, at home, in diaspora settings, in short-term and long-term sojourns abroad for study or work, and in other contexts and circumstances. In this article, I discuss some recent areas in which applied linguists have investigated the intersections of language (multilingualism), identity, and transnationalism. I then present illustrative studies and some recurring themes and issues.
(Supra)National Identity and Language: Rethinking National and European Migration Policies and the Linguistic Integration of Migrants
Authors: Wodak Ruth , Boukala Salomi 
Published: March 2015

ABSTRACTIn this paper we juxtapose the European Union's (EU's) supranational policies on language and migration with their recontextualisation into national policies of the linguistic integration of migrants in two EU member states, Austria and Greece. The EU member states adapt the European legislation according to their national laws (National Acton Plans) which have to also account for national traditions and national citizenship legislation. Moreover, we explore the national regulations on language testing and the linguistic integration of migrants in Austria and Greece which are part and parcel of the National Action Plans and which establish obstacles for migrants: Indeed, they function as gate-keepers. Hence, a context-dependent micro-level discourse analytic approach suggests itself.The data for the analysis stem from legal and policy texts of the EU, Austria and Greece (regulations on citizenship, language education, testing and the linguistic integration of migrants). By employing the Discourse Historical Approach (DHA) of Critical Discourse Studies we analyze how specific EU regulations are implemented in national legislation; how migrants, who live in Austria and Greece are represented by the legislators, and finally how the respective national identities in the context of migration legislation are constructed.
Population susceptibility to a variant swine-origin influenza virus A(H3N2) in Vietnam, 2011–2012
Authors: HOA L. N. M. , BRYANT J. E. , CHOISY M. , NGUYET L. A. , BAO N. T. , TRANG N. H. , CHUC N. T. K. , TOAN T. K. , SAITO T. , TAKEMAE N. , HORBY P. , WERTHEIM H. , FOX A. 
Published: March 2015

SUMMARYA reassortant swine-origin A(H3N2) virus (A/swine/BinhDuong/03-9/2010) was detected through swine surveillance programmes in southern Vietnam in 2010. This virus contains haemagglutinin and neuraminidase genes from a human A(H3N2) virus circulating around 2004–2006, and the internal genes from triple-reassortant swine influenza A viruses (IAVs). To assess population susceptibility to this virus we measured haemagglutination inhibiting (HI) titres to A/swine/BinhDuong/03-9/2010 and to seasonal A/Perth/16/2009 for 947 sera collected from urban and rural Vietnamese people during 2011–2012. Seroprevalence (HI ⩾ 40) was high and similar for both viruses, with 62·6% [95% confidence interval (CI) 59·4–65·7] against A/Perth/16/2009 and 54·6% (95% CI 51·4–57·8%) against A/swine/BinhDuong/03-9/2010, and no significant differences between urban and rural participants. Children aged <5 years lacked antibodies to the swine origin H3 virus despite high seroprevalence for A/Perth/16/2009. These results reveal vulnerability to infection to this contemporary swine IAV in children aged <5 years; however, cross-reactive immunity in adults would likely limit epidemic emergence potential.
Incidence of percutaneous injury in Taiwan healthcare workers
Authors: WU H. C. , HO J. J. , LIN M. H. , CHEN C. J. , GUO Y. L. , SHIAO J. S. C. 
Published: March 2015

SUMMARYReporting of percutaneous injuries (PIs) to the Chinese Exposure Prevention Information Network (EPINet) became mandatory for all public and tertiary referral hospitals in Taiwan in 2011. We have estimated the number of microbially contaminated PIs and the national PI incidence using a retrospective secondary data analysis approach to analyse 2011 data from the Chinese EPINet to determine the types of PI, mechanisms of occurrence and associated risks. The results revealed a national estimate of PIs between 6710 and 8319 in 2011. The most common incidents for physicians were disposable syringes, suture needles, and disposable scalpels; while for nurses they were disposable syringes, intravenous catheters, and lancets. About 13·0% of the source patients were seropositive for hepatitis B virus (HBV) surface antigen, 13·8% were seropositive for hepatitis C virus (HCV), and 1·1% seropositive for human immunodeficiency virus (HIV). From these results we estimate that annually 970 full-time healthcare workers (HCWs) would be exposed to HBV, 1094 to HCV, and 99 to HIV. This study improves our understanding of the mechanisms and risks of PIs and informs the development of more efficient preventive measures to protect HCWs from such injuries.
Portuguese Validation of the Consideration of Future Consequences Scale
Authors: Echeverría Alejandro Vásquez , Esteves Cristina , Gomes Catarina Vilares , Ortuño Victor E. C. 
Published: March 2015

AbstractThe Consideration of Future Consequences Scale (CFC-S) is a measure of the extent to which individuals reflect and are influenced by the immediate as well as by the distant outcomes of current behavior. It´s composed by 12 items, grouped into two subscales (future and immediate). This study aims to explore the factor structure, psychometric properties and construct validity of the Portuguese version of the CFC-S in 5 samples, composed by 527 participants with ages between 13 and 71. A 2 factor structure has been found through Confirmatory Factor Analysis among several tested models. Item 5 has been eliminated in order to achieve better fit indices (χ2df = 3.88, CFI = .90, GFI = .95, RMSEA = .07) and improve internal consistency. Both CFC subscales presented strong correlations with several psychological phenomena (Sensation Seeking, Self-Esteem, Temporal Extension and Time Perspective) and main effects among groups of age and criminal record (for CFC-I, p < .001, for CFC-F, p < .001). These results allow us to support CFC as an efficient psychological evaluation instrument and as an important metric for individual differences in the study of temporal orientation.
IL-23-mediated mononuclear phagocyte crosstalk protects mice from Citrobacter rodentium-induced colon immunopathology
Authors: Aychek Tegest , Mildner Alexander , Yona Simon , Kim Ki-Wook , Lampl Nardy , Reich-Zeliger Shlomit , Boon Louis , Yogev Nir , Waisman Ari , Cua Daniel J. , Jung Steffen 
Published: March 2015

AbstractGut homeostasis and mucosal immune defense rely on the differential contributions of dendritic cells (DC) and macrophages. Here we show that colonic CX3CR1+ mononuclear phagocytes are critical inducers of the innate response to Citrobacter rodentium infection. Specifically, the absence of IL-23 expression in macrophages or CD11b+ DC results in the impairment of IL-22 production and in acute lethality. Highlighting immunopathology as a death cause, infected animals are rescued by the neutralization of IL-12 or IFNγ. Moreover, mice are also protected when the CD103+ CD11b− DC compartment is rendered deficient for IL-12 production. We show that IL-12 production by colonic CD103+ CD11b− DC is repressed by IL-23. Collectively, in addition to its role in inducing IL-22 production, macrophage-derived or CD103− CD11b+ DC-derived IL-23 is required to negatively control the otherwise deleterious production of IL-12 by CD103+ CD11b− DC. Impairment of this critical mononuclear phagocyte crosstalk results in the generation of IFNγ-producing former TH17 cells and fatal immunopathology.
Fukushima radionuclides in the NW Pacific and assessment of doses for Japanese and world population from ingestion of seafood
Authors: Povinec Pavel P. , Hirose Katsumi 
Published: March 2015

AbstractVariations of Fukushima-derived radionuclides (90Sr, 134Cs and 137Cs) in seawater and biota offshore Fukushima and in the NW Pacific Ocean were investigated and radiation doses to the Japanese and world population from ingestion of seafood contaminated by Fukushima radionuclides were estimated and compared with those from other sources of anthropogenic and natural radionuclides. The total effective dose commitment from ingestion of radionuclides in fish, shellfish and seaweed caught in coastal waters off Fukushima was estimated to be 0.6 ± 0.4 mSv/y. The individual effective dose commitment from consumption of radioactive-contaminated fish caught in the open Pacific Ocean was estimated to be 0.07 ± 0.05 mSv/y. These doses are comparable or much lower than doses delivered from the consumption of natural 210Po in fish and in shellfish (0.7 mSv/y). The estimated individual doses have been below the levels when any health damage of the Japanese and world population could be expected.
Brassinosteroids play a critical role in the regulation of pesticide metabolism in crop plants
Authors: Zhou Yanhong , Xia Xiaojian , Yu Gaobo , Wang Jitao , Wu Jingxue , Wang Mengmeng , Yang Youxin , Shi Kai , Yu Yunlong , Chen Zhixiang , Gan Jay , Yu Jingquan 
Published: March 2015

AbstractPesticide residues in agricultural produce pose a threat to human health worldwide. Although the detoxification mechanisms for xenobiotics have been extensively studied in mammalian cells, information about the regulation network in plants remains elusive. Here we show that brassinosteroids (BRs), a class of natural plant hormones, decreased residues of common organophosphorus, organochlorine and carbamate pesticides by 30–70% on tomato, rice, tea, broccoli, cucumber, strawberry and other plants when treated externally. Genome-wide microarray analysis showed that fungicide chlorothalonil (CHT) and BR co-upregulated 301 genes, including a set of detoxifying genes encoding cytochrome P450, oxidoreductase, hydrolase and transferase in tomato plants. The level of BRs was closely related to the respiratory burst oxidase 1 (RBOH1)-encoded NADPH oxides-dependent H2O2 production, glutathione biosynthesis and the redox homeostasis and the activity of glutathione S-transferase (GST). Gene silencing treatments showed that BRs decreased pesticide residues in plants likely by promoting their metabolism through a signaling pathway involving BRs-induced H2O2 production and cellular redox change. Our study provided a novel approach for minimizing pesticide residues in crops by exploiting plants' own detoxification mechanisms.
Laplacian spectra of a class of small-world networks and their applications
Authors: Liu Hongxiao , Dolgushev Maxim , Qi Yi , Zhang Zhongzhi 
Published: March 2015

AbstractOne of the most crucial domains of interdisciplinary research is the relationship between the dynamics and structural characteristics. In this paper, we introduce a family of small-world networks, parameterized through a variable d controlling the scale of graph completeness or of network clustering. We study the Laplacian eigenvalues of these networks, which are determined through analytic recursive equations. This allows us to analyze the spectra in depth and to determine the corresponding spectral dimension. Based on these results, we consider the networks in the framework of generalized Gaussian structures, whose physical behavior is exemplified on the relaxation dynamics and on the fluorescence depolarization under quasiresonant energy transfer. Although the networks have the same number of nodes (beads) and edges (springs) as the dual Sierpinski gaskets, they display rather different dynamic behavior.
Production of diacetyl by metabolically engineered Enterobacter cloacae
Authors: Zhang Lijie , Zhang Yingxin , Liu Qiuyuan , Meng Liying , Hu Mandong , Lv Min , Li Kun , Gao Chao , Xu Ping , Ma Cuiqing 
Published: March 2015

AbstractDiacetyl, a high value product that can be extensively used as a food ingredient, could be produced from the non-enzymatic oxidative decarboxylation of α-acetolactate during 2,3-butanediol fermentation. In this study, the 2,3-butanediol biosynthetic pathway in Enterobacter cloacae subsp. dissolvens strain SDM, a good candidate for microbial 2,3-butanediol production, was reconstructed for diacetyl production. To enhance the accumulation of the precursor of diacetyl, the α-acetolactate decarboxylase encoding gene (budA) was knocked out in strain SDM. Subsequently, the two diacetyl reductases DR-I (gdh) and DR-II (budC) encoding genes were inactivated in strain SDM individually or in combination to decrease the reduction of diacetyl. Although the engineered strain E. cloacae SDM (ΔbudAΔbudC) was found to have a good ability for diacetyl production, more α-acetolactate than diacetyl was produced simultaneously. In order to enhance the nonenzymatic oxidative decarboxylation of α-acetolactate to diacetyl, 20 mM Fe3+ was added to the fermentation broth at the optimal time. In the end, by using the metabolically engineered strain E. cloacae SDM (ΔbudAΔbudC), diacetyl at a concentration of 1.45 g/L was obtained with a high productivity (0.13 g/(L·h)). The method developed here may be a promising process for biotechnological production of diacetyl.
Allostery through protein-induced DNA bubbles
Authors: Traverso Joseph J. , Manoranjan Valipuram S. , Bishop A. R. , Rasmussen Kim Ø. , Voulgarakis Nikolaos K. 
Published: March 2015

AbstractAllostery through DNA is increasingly recognized as an important modulator of DNA functions. Here, we show that the coalescence of protein-induced DNA bubbles can mediate allosteric interactions that drive protein aggregation. We propose that such allostery may regulate DNA's flexibility and the assembly of the transcription machinery. Mitochondrial transcription factor A (TFAM), a dual-function protein involved in mitochondrial DNA (mtDNA) packaging and transcription initiation, is an ideal candidate to test such a hypothesis owing to its ability to locally unwind the double helix. Numerical simulations demonstrate that the coalescence of TFAM-induced bubbles can explain experimentally observed TFAM oligomerization. The resulting melted DNA segment, approximately 10 base pairs long, around the joints of the oligomers act as flexible hinges, which explains the efficiency of TFAM in compacting DNA. Since mitochondrial polymerase (mitoRNAP) is involved in melting the transcription bubble, TFAM may use the same allosteric interaction to both recruit mitoRNAP and initiate transcription.
Learning-related brain hemispheric dominance in sleeping songbirds
Authors: Moorman Sanne , Gobes Sharon M. H. , van de Kamp Ferdinand C. , Zandbergen Matthijs A. , Bolhuis Johan J. 
Published: March 2015

AbstractThere are striking behavioural and neural parallels between the acquisition of speech in humans and song learning in songbirds. In humans, language-related brain activation is mostly lateralised to the left hemisphere. During language acquisition in humans, brain hemispheric lateralisation develops as language proficiency increases. Sleep is important for the formation of long-term memory, in humans as well as in other animals, including songbirds. Here, we measured neuronal activation (as the expression pattern of the immediate early gene ZENK) during sleep in juvenile zebra finch males that were still learning their songs from a tutor. We found that during sleep, there was learning-dependent lateralisation of spontaneous neuronal activation in the caudomedial nidopallium (NCM), a secondary auditory brain region that is involved in tutor song memory, while there was right hemisphere dominance of neuronal activation in HVC (used as a proper name), a premotor nucleus that is involved in song production and sensorimotor learning. Specifically, in the NCM, birds that imitated their tutors well were left dominant, while poor imitators were right dominant, similar to language-proficiency related lateralisation in humans. Given the avian-human parallels, lateralised neural activation during sleep may also be important for speech and language acquisition in human infants.
Fisetin exerts antihyperalgesic effect in a mouse model of neuropathic pain: engagement of spinal serotonergic system
Authors: Zhao Xin , Wang Chuang , Cui Wu-Geng , Ma Qing , Zhou Wen-Hua 
Published: March 2015

AbstractFisetin, a natural flavonoid, has been shown in our previous studies to exert antidepressant-like effect. As antidepressant drugs are clinically used to treat chronic neuropathic pain, this work aimed to investigate the potential antinociceptive efficacies of fisetin against neuropathic pain and explore mechanism(s). We subjected mice to chronic constriction injury (CCI) by loosely ligating the sciatic nerves and Hargreaves test or von Frey test was used to assess thermal hyperalgesia or mechanical allodynia, respectively. Chronic fisetin treatment (5, 15 or 45 mg/kg, p.o.) ameliorated thermal hyperalgesia (but not mechanical allodynia) in CCI mice, concomitant with escalated levels of spinal monoamines and suppressed monoamine oxidase (MAO)-A activity. The antihyperalgesic action of fisetin was abolished by chemical depletion of spinal serotonin (5-HT) but potentiated by co-treatment with 5-HTP, a precursor of 5-HT. Moreover, intraperitoneal (i.p.) or intrathecal (i.t.) co-treatment with 5-HT7 receptor antagonist SB-258719 completely abrogated fisetin's antihyperalgesia. These findings confirm that chronic fisetin treatment exerts antinociceptive effect on thermal hyperalgesia in neuropathic mice, with spinal serotonergic system (coupled with 5-HT7) being critically involved. Of special benefit, fisetin attenuated co-morbidly behavioral symptoms of depression and anxiety (evaluated in forced swim test, novelty suppressed feeding test and light-dark test) evoked by neuropathic pain.
Growth of a deep-water, predatory fish is influenced by the productivity of a boundary current system
Authors: Nguyen Hoang Minh , Rountrey Adam N. , Meeuwig Jessica J. , Coulson Peter G. , Feng Ming , Newman Stephen J. , Waite Anya M. , Wakefield Corey B. , Meekan Mark G. 
Published: March 2015

AbstractThe effects of climate change on predatory fishes in deep shelf areas are difficult to predict because complex processes may govern food availability and temperature at depth. We characterised the net impact of recent environmental changes on hapuku (Polyprion oxygeneios), an apex predator found in continental slope habitats (>200 m depth) by using dendrochronology techniques to develop a multi-decadal record of growth from otoliths. Fish were sampled off temperate south-western Australia, a region strongly influenced by the Leeuwin Current, a poleward-flowing, eastern boundary current. The common variance among individual growth records was relatively low (3.4%), but the otolith chronology was positively correlated (r = 0.61, p < 0.02) with sea level at Fremantle, a proxy for the strength of the Leeuwin Current. The Leeuwin Current influences the primary productivity of shelf ecosystems, with a strong current favouring growth in hapuku. Leeuwin Current strength is predicted to decline under climate change models and this study provides evidence that associated productivity changes may flow through to higher trophic levels even in deep water habitats.