bluuebunny/crossref_metadata_2025_split huggingface dataset:
Supplier relationship‐specific investments and the role of safeguards for supplier innovation sharing
Authors: Wagner Stephan M. , Bode Christoph 
Published: November 2013

AbstractThe vast majority of the supplier innovation literature has focused on how buying firms can effectively “pull” innovations from their suppliers. Yet, we know remarkably little about the factors that contribute to a supplier voluntarily “pushing” innovations to its customers. The present study addresses this research gap in the context of industrial buyer–supplier relationships and with a specific focus on relationship‐specific investments. Drawing on theory from the relationship‐marketing literature and on transaction cost theory, we devise and test a proposed theoretical model that links the level of a supplier's relationship‐specific investments to its sharing of innovative ideas regarding products and processes with customers. The model also considers the role of contract length, relationship age, and buyer–supplier cooperation as possible safeguards. The empirical results suggest that a supplier's relationship‐specific investments encourage a supplier to suggest ideas of process innovations but to refrain from suggestions about product innovations. The latter effect, however, can be attenuated by appropriate formal and informal safeguards.
Functional characterization of a novel FGFR1OP‐RET rearrangement in hematopoietic malignancies
Authors: Bossi Daniela , Carlomagno Francesca , Pallavicini Isabella , Pruneri Giancarlo , Trubia Maurizio , Raviele Paola Rafaniello , Marinelli Alessandra , Anaganti Suresh , Cox Maria Christina , Viale Giuseppe , Santoro Massimo , Di Fiore Pier Paolo , Minucci Saverio 
Published: November 2013

The RET (REarranged during Transfection) receptor tyrosine kinase is targeted by oncogenic rearrangements in thyroid and lung adenocarcinoma. Recently, a RET (exon 12) rearrangement with FGFR1OP [fibroblast growth factor receptor 1 (FGFR1) oncogene partner] (exon 12) was identified in one chronic myelomonocytic leukemia (CMML) patient. We report the molecular cloning and functional characterization of a novel FGFR1OP (exon 11)‐RET (exon 11) gene fusion event (named FGFR1OP‐RET), mediated by a reciprocal translocation t(6; 10)(q27; q11), in a patient affected by primary myelofibrosis (PMF) with secondary acute myeloid leukemia (AML). The FGFR1OP‐RET fusion protein displayed constitutive tyrosine kinase and transforming activity in NIH3T3 fibroblasts, and induced IL3‐independent growth and activation of PI3K/STAT signaling in hematopoietic Ba/F3 cells. FGFR1OP‐RET supported cytokine‐independent growth, protection from stress and enhanced self‐renewal of primary murine hematopoietic progenitor and stem cells in vitro. In vivo, FGFR1OP‐RET caused a spectrum of disease phenotypes, with >50% of mice showing a fatal myeloproliferative disorder (MPD). Other phenotypes were leukemia transplantable in secondary recipients, dramatic expansion of the mast cell lineage, and reduction of repopulating activity upon lethal irradiation. In conclusion, FGFR1OP‐RET chimeric oncogenes are endowed with leukemogenic potential and associated to myeloid neoplasms (CMML and PMF/AML).
Native iron in Quaternary deposits of the Darhad Basin (northern Mongolia)
Authors: Pechersky D.M. , Gil’manova D.M. , Kazansky A.Yu. , Krivonogov S.K. , Nurgaliev D.K. , Tsel’movich V.A. 
Published: November 2013

Abstract
Quaternary sediments from the borehole DBC-1 drilled in the Darhad Basin, northern Mongolia, have been studied by thermomagnetic analysis (248 samples) and probe microanalysis (9 samples) to determine the origin (cosmic or terrestrial) of native iron. Most of the samples showed extremely low contents of native iron. Only 26 samples have iron in contents sufficient for its reliable identification (10–5–10–3%). The negligible content of native iron in the Darhad Basin sediments distinguishes them from the earlier studied sediments of different geologic associations of Eurasia and the Atlantic, which we explain by the high sedimentation rate in this basin. However, the bimodal distribution of native-iron contents in the samples with a distinct “zero” mode, similar to that in the objects of Eurasia and the Atlantic, testifies to the predominantly cosmic origin of the native iron.
Value Distribution and Linear Operators
Authors: Halburd R. , Korhonen R. 
Published: November 2013

AbstractNevanlinna's second main theorem is a far-reaching generalization of Picard's theorem concerning the value distribution of an arbitrary meromorphic function f. The theorem takes the form of an inequality containing a ramification term in which the zeros and poles of the derivative f′ appear. We show that a similar result holds for special subfields of meromorphic functions where the derivative is replaced by a more general linear operator, such as higher-order differential operators and differential-difference operators. We subsequently derive generalizations of Picard's theorem and the defect relations.
DO THE FACTORS ASSOCIATED WITH FEMALE HIV INFECTION VARY BY SOCIOECONOMIC STATUS IN CAMEROON?
Authors: MUMAH JOYCE N. , JACKSON-SMITH DOUGLAS 
Published: November 2013

SummaryOne of the most consistent findings in social epidemiology is an inverse relationship between indicators of SES and most types of illness. However, a growing body of research on HIV in sub-Saharan Africa suggests an intriguing reversal of this pattern, particularly with respect to HIV among women. In Cameroon, specifically, high-SES women have higher rates of HIV infection compared with low-SES women. Using data from the 2004 Cameroon DHS, this study explored the relationships between SES and HIV and tested a multivariate model designed to highlight the distinctive factors associated with increased risk of HIV among women in different SES classes. The results revealed that high-SES women who reported engaging in riskier sexual behaviour had the highest levels of HIV infection. Surprisingly, among this group increased knowledge of HIV, more domestic decision-making authority and access to health care did not reduce vulnerability. Meanwhile, among low-SES women relative gender inequality was significantly related to HIV risk. Specifically, among this group of women, having a partner with higher education was strongly associated with greater HIV risk. The results suggest that different approaches targeting each sub-group are needed to effectively combat the disease.
Low-dimensional relativistic degeneracy in quantum plasmas
Authors: AKBARI-MOGHANJOUGHI M. , ESFANDYARI-KALEJAHI A. 
Published: November 2013

AbstractIn this work we investigate the effect of relativistic degeneracy on different properties of low-dimensional quantum plasmas. Using the dielectric response from the conventional quantum hydrodynamic model, including the quantum diffraction effect (Bohm potential) on free electrons, we explore the existence of the Shukla–Eliasson attractive screening and possibility of the ion structure formation in low-dimensional, completely degenerate electron–ion plasmas. A generalized degeneracy pressure expression for arbitrary relativity parameter in two-dimensional case is derived, indicating that change in the polytropic index (change in the equation of state) for the two-dimensional quantum fluid takes place at the electron number-density of n0 ≃ 1.1 × 1020cm−2 whereas this is known to occur for the three-dimensional case in the electron density of n0 ≃ 5.9 × 1029cm−3. Also, a generalized dielectric function valid for all dimensionalities and densities of a degenerate electron gas is calculated, and distinct properties of electron–ion plasmas, such as static screening, structure factor and Thomson scattering, are investigated in terms of plasma dimensionality.
A manuscript history of the Franklin family by Sophia Cracroft (1853)
Authors: McCorristine Shane 
Published: November 2013

ABSTRACTSir John Franklin's widow, Jane Franklin, planned a biography of her husband in the years following the disappearance of his expedition. In this project she was directly assisted by her niece and amanuensis Sophia Cracroft. This biography never came to fruition, but it did result in an unpublished manuscript history of the Franklin family, dated 1853, which Cracroft shared with Franklin's early biographers. The manuscript provides an interesting account of the Franklin family, including the detailed circumstances of the failure of the Boston and Spilsby Bank in 1804, which caused great financial and emotional stress. The final section of the manuscript provides an account of John Franklin's early naval career and Arctic expeditions.
Transforming the self: on the baptismal rite
Authors: CUNEO TERENCE 
Published: November 2013

AbstractPhilosophers have paid almost no attention to the baptismal rite. This is puzzling not only because the rite is central to the Christian life but also because the rite itself is very puzzling, making audacious claims about what its performance accomplishes. According to one of these audacious claims, by the performance of the rite the one baptized is transformed, enjoying states such as purification, sanctification, regeneration, and illumination – what I call theregenerate states. But how could this be so? And isn't there good empirical evidence that the imposition of the regenerate states on the one baptized is not accomplished in the vast majority of cases? In this article, I consider an ancient and audacious version of the baptismal rite, namely, that used by Eastern Orthodox Christians. I propose a model for understanding this rite – what I call theprocess-interpretation – which I believe comes close to being satisfactory, since it implies that the imposition of the regenerate states is not nearly as perplexing as it might seem at first glance.
Don't count your chickens before they're hatched: Elaborative encoding in REM dreaming in face of the physiology of sleep stages
Authors: Deliens Gaétane , Schwartz Sophie , Peigneux Philippe 
Published: November 2013

AbstractLlewellyn suggests that episodic memories undergo “elaborative encoding” during rapid eye movement (REM) dreams, generating novel associations between recent and remote memories that are then instantiated during non-REM (NREM) sleep. This hypothesis conflicts with our knowledge of the physiology of NREM and then REM sleep stages and their ordered succession. Moreover, associations during sleep might also involve the extraction of hidden patterns rather than de novo associations.
“They who dream by day”: Parallels between Openness to Experience and dreaming
Authors: DeYoung Colin G. , Grazioplene Rachael G. 
Published: November 2013

AbstractIndividuals high in the personality trait Openness to Experience appear to engage spontaneously (during wake) in processes of elaborative encoding similar to those Llewellyn identifies in both dreaming and the ancient art of memory (AAOM). Links between Openness and dreaming support the hypothesis that dreaming is part of a larger process of cognitive exploration that facilitates adaptation to new experiences.
REM sleep and dreaming functions beyond reductionism
Authors: Kirov Roumen 
Published: November 2013

AbstractBrain activation patterns and mental, electrophysiological, and neurobiological features of rapid eye movement (REM) sleep suggest more functions than only elaborative encoding. Hence, the periodic occurrence of REM sleep episodes and dreaming may be regarded as a recurrent adaptive interference, which incorporates recent memories into a broader vital context comprising emotions, basic needs and individual genetic traits.
The spaces left over between REM sleep, dreaming, hippocampal formation, and episodic autobiographical memory
Authors: Markowitsch Hans J. , Staniloiu Angelica 
Published: November 2013

AbstractIt is argued that Llewellyn's hypothesis about the lack of rapid eye movement (REM)-sleep dreaming leading to loss of personal identity and deficits in episodic memory, affectivity, and prospection is insufficiently grounded because it does not integrate data from neurodevelopmental studies and makes reference to an outdated definition of episodic memory.
Studying the relationship between dreaming and sleep-dependent memory processes: Methodological challenges
Authors: Schredl Michael 
Published: November 2013

AbstractThe hypothesis that dreaming is involved in off-line memory processing is difficult to test because major methodological issues have to be addressed, such as dream recall and the effect of remembered dreams on memory. It would be fruitful – in addition to studying the ancient art of memory (AAOM) in a scanner – to study the dreams of persons who use AAOM regularly.
Captions and reduced forms instruction: The impact on EFL students’ listening comprehension
Authors: Yang Jie Chi , Chang Peichin 
Published: November 2013

AbstractFor many EFL learners, listening poses a grave challenge. The difficulty in segmenting a stream of speech and limited capacity in short-term memory are common weaknesses for language learners. Specifically, reduced forms, which frequently appear in authentic informal conversations, compound the challenges in listening comprehension. Numerous interventions have been implemented to assist EFL language learners, and of these, the application of captions has been found highly effective in promoting learning. Few studies have examined how different modes of captions may enhance listening comprehension. This study proposes three modes of captions: full, keyword-only, and annotated keyword captions and investigates their contribution to the learning of reduced forms and overall listening comprehension. Forty-four EFL university students participated in the study and were randomly assigned to one of the three groups. The results revealed that all three groups exhibited improvement on the pre-test while the annotated keyword caption group exhibited the best performance with the highest mean score. Comparing performances between groups, the annotated keyword caption group also emulated both the full caption and the keyword-only caption groups, particularly in the ability to recognize reduced forms. The study sheds light on the potential of annotated keyword captions in enhancing reduced forms learning and overall listening comprehension.
Is less more? Effectiveness and perceived usefulness of keyword and full captioned video for L2 listening comprehension
Authors: Montero Perez Maribel , Peters Elke , Desmet Piet 
Published: November 2013

AbstractThe aim of this study was twofold: we investigated (a) the effect of two types of captioned video (i.e., on-screen text in the same language as the video) on listening comprehension; (b) L2 learners’ perception of the usefulness of captions while watching L2 video. The participants, 226 university-level students from a Flemish university, watched three short French clips in one of three conditions: the control group watched the clips without captions (N = 70), the second group had fully captioned clips (N = 81), the third group had keyword captioned clips (N = 75). After each clip, all participants took a listening comprehension test, which consisted of global and detailed questions. To answer the detailed questions, participants had access to an audio passage of the corresponding clip. At the end of the experiment, participants completed a questionnaire and open-ended survey questions about their perception of captions. Our findings revealed that the full captioning group outperformed both the no captioning and the keyword captioning group on the global comprehension questions. However, no difference was found between the keyword captioning and the no captioning group. Results of the detailed comprehension questions (with audio) revealed no differences between the three conditions. A content-analysis approach to the questionnaire indicated that learners’ perceived need for full captions is strong. Participants consider captions useful for speech decoding and meaning-making processes. Surprisingly, keyword captions were considered highly distracting. These findings suggest that full rather than keyword captioning should be considered when proposing video-based listening comprehension activities to L2 learners.
DNA Translocation through Hydrophilic Nanopore in Hexagonal Boron Nitride
Authors: Zhou Zhi , Hu Ying , Wang Hao , Xu Zhi , Wang Wenlong , Bai Xuedong , Shan Xinyan , Lu Xinghua 
Published: November 2013

AbstractUltra-thin solid-state nanopore with good wetting property is strongly desired to achieve high spatial resolution for DNA sequencing applications. Atomic thick hexagonal boron nitride (h-BN) layer provides a promising two-dimensional material for fabricating solid-state nanopores. Due to its good oxidation resistance, the hydrophilicity of h-BN nanopore device can be significantly improved by UV-Ozone treatment. The contact angle of a KCl-TE droplet on h-BN layer can be reduced from 57° to 26° after the treatment. Abundant DNA translocation events have been observed in such devices and strong DNA-nanopore interaction has been revealed in pores smaller than 10 nm in diameter. The 1/f noise level is closely related to the area of suspended h-BN layer and it is significantly reduced in smaller supporting window. The demonstrated performance in h-BN nanopore paves the way towards base discrimination in a single DNA molecule.
AGO61-dependent GlcNAc modification primes the formation of functional glycans on α-dystroglycan
Authors: Yagi Hirokazu , Nakagawa Naoki , Saito Takuya , Kiyonari Hiroshi , Abe Takaya , Toda Tatsushi , Wu Sz-Wei , Khoo Kay-Hooi , Oka Shogo , Kato Koichi 
Published: November 2013

AbstractDystroglycanopathy is a major class of congenital muscular dystrophy that is caused by a deficiency of functional glycans on α-dystroglycan (α-DG) with laminin-binding activity. A product of a recently identified causative gene for dystroglycanopathy, AGO61, acted in vitro as a protein O-mannose β-1, 4-N-acetylglucosaminyltransferase, although it was not functionally characterized. Here we show the phenotypes of AGO61-knockout mice and demonstrate that AGO61 is indispensable for the formation of laminin-binding glycans of α-DG. AGO61-knockout mouse brain exhibited abnormal basal lamina formation and a neuronal migration defect due to a lack of laminin-binding glycans. Furthermore, our results indicate that functional α-DG glycosylation was primed by AGO61-dependent GlcNAc modifications of specific threonine-linked mannosyl moieties of α-DG. These findings provide a key missing link for understanding how the physiologically critical glycan motif is displayed on α-DG and provides new insights on the pathological mechanisms of dystroglycanopathy.
Beginning to Talk Like an Adult: Increases in Speech-Like Utterances in Young Cochlear Implant Recipients and Typically Developing Children
Authors: Ertmer David J. , Jung Jongmin , Kloiber Diana True 
Published: November 2013

Purpose
Speech-like utterances containing rapidly combined consonants and vowels eventually dominate the prelinguistic and early word productions of typically developing (TD) toddlers. It seems reasonable to expect a similar phenomenon in young recipients of cochlear implants (CIs). The authors of this study sought to determine the number of months of robust hearing experience needed to achieve a majority of speech-like utterances in both of these groups.

Method
Speech samples were recorded from CI recipients at 3-month intervals during the first 2 years of CI experience, and from TD children at time points between 6 and 24 months of age. Speech-like utterances were operationally defined as those belonging to the basic canonical syllables (BCS) or advanced forms (AF) levels of the Consolidated Stark Assessment of Early Vocal Development—Revised (Ertmer, Young, & Nathani, 2007).

Results
On average, the CI group achieved a majority of speech-like utterances after 12 months of robust hearing experience and the TD group after 18 months. The CI group produced greater percentages of speech-like utterances at each interval until 24 months, when both groups approximated 80%.

Conclusion
Auditory deprivation did not limit progress in vocal development as young CI recipients showed more-rapid-than-typical speech development during the first 2 years of device use. Implications for the infraphonological model of speech development are considered.
Multiple Myeloma-Associated Amyloidoma of the Sacrum: Case Report and Review of the Literature
Authors: Klenke F. M. , Wirtz C. , Banz Y. , Keel M. J. B. , Klass N. D. , Novak U. , Benneker L. M. 
Published: November 2013

Study Design Case report. Objectives With only two previously reported cases, localized amyloidosis of the sacrum is extremely rare. Here we report a 64-year-old woman with a large osteolytic lesion accompanied by weakness and paresthesia of the right leg and difficulties in bladder control. Methods Fine needle biopsy and standard staging procedures revealed a primary solitary amyloidoma that was treated with intralesional resection, lumbopelvic stabilization, and consolidation radiotherapy. Results Clinical follow-up revealed the diagnosis of multiple myeloma 9 months after initial treatment. At 12 months, no local recurrence has occurred, the neurologic symptoms have resolved, and the systemic disease is in remission. Conclusions Intralesional resection with adjuvant radiotherapy of the amyloidoma achieved good local tumor control with limited morbidity.
On the simultaneous association analysis of large genomic regions: a massive multi-locus association test
Authors: Qiao Dandi , Cho Michael H. , Fier Heide , Bakke Per S. , Gulsvik Amund , Silverman Edwin K. , Lange Christoph 
Published: November 2013

Abstract
Motivation: For samples of unrelated individuals, we propose a general analysis framework in which hundred thousands of genetic loci can be tested simultaneously for association with complex phenotypes. The approach is built on spatial-clustering methodology, assuming that genetic loci that are associated with the target phenotype cluster in certain genomic regions. In contrast to standard methodology for multilocus analysis, which has focused on the dimension reduction of the data, our multilocus association-clustering test profits from the availability of large numbers of genetic loci by detecting clusters of loci that are associated with the phenotype.
Results: The approach is computationally fast and powerful, enabling the simultaneous association testing of large genomic regions. Even the entire genome or certain chromosomes can be tested simultaneously. Using simulation studies, the properties of the approach are evaluated. In an application to a genome-wide association study for chronic obstructive pulmonary disease, we illustrate the practical relevance of the proposed method by simultaneously testing all genotyped loci of the genome-wide association study and by testing each chromosome individually. Our findings suggest that statistical methodology that incorporates spatial-clustering information will be especially useful in whole-genome sequencing studies in which millions or billions of base pairs are recorded and grouped by genomic regions or genes, and are tested jointly for association.
Availability and implementation: Implementation of the approach is available upon request.
Contact: daq412@mail.harvard.edu
Supplementary information: Supplementary data are available at Bioinformatics online.