bluuebunny/crossref_metadata_2025_split huggingface dataset:
Interprofessional student-run primary health care clinics
Authors: Weidmann Anita E. , Pammett Robert , Landry Eric , Jorgenson Derek 
Published: April 2015

Introduction: Interprofessional student-run primary health care clinics have been a flagship model of health professional education in Canada for many years. The purpose of this study was to determine if there is support for implementing this educational model in the United Kingdom and to highlight the implications for pharmacy education in Scotland. Method: A cross-sectional postal survey of 3000 randomly selected citizens of Aberdeen city and shire, Scotland, aged 18 years and older. Results: Of the 824 questionnaires that were returned (response rate 27.5%), more than half of the respondents (62.4%; n = 514) would consider accessing health care from a student-led, walk-in service. The range of services they expect to see includes general health checks (60%; n = 494), help for sexually transmitted diseases (57.5%; n = 474), weight management (56.8%; n = 468), smoking cessation (54.4%; n = 448) and drug misuse services (47.2%; n = 387). Concerns raised pertained to student ability, suitability for children and accessibility. Many comments pertained to the improvement of the current system by offering after-hours care. Discussion: The positive response from the general public towards an interprofessional student-run primary health care clinic in Aberdeen suggests that this Canadian model of interdisciplinary health professional education would likely be a successful addition to the pharmacy curriculum in Scotland.
A calibrated measuring tape accurately predicts tidal volumes from ulna length
Authors: Rivers Jon , Brown Jules , Dolphin Kirsty , Squire Yolande 
Published: April 2015

Background Low tidal volume ventilation improves outcomes in acute respiratory distress syndrome. Calculation of this volume requires knowledge of a patient’s gender, and height, which may not be available in emergency admissions, and the subsequent application of a nomogram. The objective of this study was to test the accuracy of a calibrated measuring tape that reads in mL of tidal volume when the ulna is measured. Methods The measuring tape was used to obtain an estimate of a subject’s tidal volume from their ulna length, and standing height was then measured (reference method). Result A total of 100 healthy volunteers were included. Mean tidal volume was 450 mL for males and 372 mL for females when calculated from the height. Comparing tidal volumes from the tape with those from the reference method, Bland Altman analysis showed a bias of −10 mL (limits of agreement (2SD) −74 mL to 54 mL) for males and a bias of −36 mL (limits of agreement (2SD) −88 mL to 16 mL) for females. Predicted mean tidal volumes were 5.7 mL/kg (95% CI: 5.1–6.3 mL/kg) for males and 5.8 mL/kg (95% CI: 5.3–6.2 mL/kg) for females. Conclusions Usage of a calibrated measuring tape produced accurate estimates of tidal volumes required for lung protective ventilation in healthy volunteers.
DNA-functionalized silicon nitride nanopores for sequence-specific recognition of DNA biosensor
Authors: Tan Shengwei , Wang Lei , Yu Jingjing , Hou Chuanrong , Jiang Rui , Li Yanping , Liu Quanjun 
Published: April 2015

Abstract
Nanopores have been proven to be novel and versatile single-molecule sensors for individual unlabeled biopolymer detection and characterization. In the present study, a relatively large silicon nitride (Si3N4) nanopore with a diameter of approximately 60 nm was fabricated successfully using a focused Ga ion beam (FIB). We demonstrated a simple ex situ silanization procedure to control the size and functionality of solid-state nanopores. The presented results show that by varying the silanization time, it is possible to adjust the efficiency of probe molecule attachment, thus shrinking the pore to the chosen size, while introducing selective sensing probes. The functionalization of nanopores was verified by analysis of field-emission scanning electron microscopy (FESEM), energy-dispersive X-ray spectroscopy (EDS), and electrical measurements. Based on this study, we envision that the functionalized silicon nitride nanopores with the DNA probe might provide a biosensing platform for the detection and discrimination of a short single-stranded DNA oligomer of unknown sequences in the future.
An international multicenter retrospective study of Pseudomonas aeruginosa nosocomial pneumonia: impact of multidrug resistance
Authors: Micek Scott T , Wunderink Richard G , Kollef Marin H , Chen Catherine , Rello Jordi , Chastre Jean , Antonelli Massimo , Welte Tobias , Clair Bernard , Ostermann Helmut , Calbo Esther , Torres Antoni , Menichetti Francesco , Schramm Garrett E , Menon Vandana 
Published: April 2015

AbstractIntroductionPseudomonas aeruginosanosocomial pneumonia (Pa-NP) is associated with considerable morbidity, prolonged hospitalization, increased costs, and mortality.MethodsWe conducted a retrospective cohort study of adult patients withPa-NP to determine 1) risk factors for multidrug-resistant (MDR) strains and 2) whether MDR increases the risk for hospital death. Twelve hospitals in 5 countries (United States, n = 3; France, n = 2; Germany, n = 2; Italy, n = 2; and Spain, n = 3) participated. We compared characteristics of patients who had MDR strains to those who did not and derived regression models to identify predictors of MDR and hospital mortality.ResultsOf 740 patients withPa-NP, 226 patients (30.5%) were infected with MDR strains. In multivariable analyses, independent predictors of multidrug-resistance included decreasing age (adjusted odds ratio [AOR] 0.91, 95% confidence interval [CI] 0.96-0.98), diabetes mellitus (AOR 1.90, 95% CI 1.21-3.00) and ICU admission (AOR 1.73, 95% CI 1.06-2.81). Multidrug-resistance, heart failure, increasing age, mechanical ventilation, and bacteremia were independently associated with in-hospital mortality in the Cox Proportional Hazards Model analysis.ConclusionsAmong patients withPa-NP the presence of infection with a MDR strain is associated with increased in-hospital mortality. Identification of patients at risk of MDRPa-NP could facilitate appropriate empiric antibiotic decisions that in turn could lead to improved hospital survival.
A reservation-based call admission control scheme and system modeling in 4G vehicular networks
Authors: Halabian Hassan , Rengaraju Perumalraja , Lung Chung-Horng , Lambadaris Ioannis 
Published: April 2015

Abstract
In 4G cellular networks, call admission control (CAC) has a direct impact on quality of service (QoS) for individual connections and overall system efficiency. Reservation-based CAC schemes have been previously proposed for cellular networks where a certain amount of system bandwidth is reserved for high-priority calls, e.g., hand-off calls and real-time new calls. Traditional reservation-based schemes are not efficient for 4G vehicular networks, as the reserved bandwidth may not be utilized effectively in low hand-off rates. We propose a channel borrowing approach in which new best effort (BE) calls can borrow the reserved bandwidth for high-priority calls. Later, if a hand-off call arrives and all the channels are busy, it will pre-empt the service of a borrower BE call if there exists any. The pre-empted BE calls are kept in a queue and resume their service whenever a channel becomes available. The analytical model for this scheme is a mixed loss-queueing system for which it is difficult to calculate call blocking probability (CBP) and call dropping probability (CDP). Our focus in this paper is on the system modeling and performance evaluation of the proposed scheme. We present two system models that approximate the operation of the proposed scheme. For these models, we derive the CBP and CDP analytically. It is shown that our analytical results are very close to the ones obtained from simulations. Furthermore, it is observed that our channel borrowing approach decreases the CBP considerably while increases the CDP slightly over a large range of hand-off rates.
Association of glutathione S-transferase (GSTM1 and GSTT1) genes with chronic myeloid leukemia
Authors: Kassogue Yaya , Dehbi Hind , Quachouh Meryem , Quessar Asma , Benchekroun Said , Nadifi Sellama 
Published: April 2015

AbstractChronic myeloid leukemia (CML), as most of cancers results from a complex interaction between genetic or non genetic factors. Exposures to xenobiotics endogenous or exogenous associated with a reduced individual ability in detoxifying activity, constitutes a risk of developing cancer. It is known that polymorphism of glutathione S-transferases (GSTs) genes affects the detoxification of xenobiotics. Thus, we conducted a case-control study in which 92 patients (Mean age ± SD, 40.62 ± 12.7 years) with CML and 93 healthy unrelated controls (Mean age ± SD, 41.38 ± 13.4 years) have participated.GSTM1andGSTT1genotypes were determined by multiplex polymerase chain reaction. Logistic regression was used to assess the possible link betweenGSTM1andGSTT1null genotypes and CML as well as between combined genotypes and CML.GSTM1null genotype frequency was slightly higher in patients than control (48.9% vs. 40.9%) but, it was not associated with CML (OR 95% CI, 1.4, 0.78-2.48; p = 0.271). Moreover,GSTT1null genotype frequency showed a similar trend between patients and control (17.4% vs. 9.7%; OR 95% CI, 1.97, 0.82-4.71; p = 0.13). Surprisingly,GSTT1null genotype was significantly associated with the risk of CML in males (OR 95% CI, 5, 1.25-20.1; p = 0.023). The combinedGSTM1present/GSTT1null genotype was found to have a limited effect against the risk of CML (OR 95% CI, 0.3, 0.08-0.99; p = 0.049). Our findings have shown thatGSTT1null genotype might be a risk factor of CML in males. While,GSTT1present genotype might be considered as protective against CML. However, further studies with a large sample size are needed to confirm our findings.
Taxane-cisplatin-fluorouracil as induction chemotherapy for advanced head and neck cancer: a meta-analysis of the 5-year efficacy and safety
Authors: Qian Xu , Ma Chenming , Hoffmann Thomas K , Kaufmann Andreas M , Albers Andreas E 
Published: April 2015

Abstract

Background
The objective of this study was to compare the efficacy and safety of taxane (docetaxel or paclitaxel), cisplatin, and fluorouracil (Tax-PF) with cisplatin plus fluorouracil (PF) regimen by a meta-analysis of data retrieved from the literature.

Methods
Seven randomized clinical trials were identified, which included patients with advanced head and neck cancer who underwent induction chemotherapy with either a Tax-PF or PF protocol. The outcomes included the 3-year and 5-year overall survival (OS) and progression-free survival (PFS), overall response rate (ORR) and different types of adverse events.

Results
The 3-year OS rate (HR: 1.14; 95% CI: 1.03 to 1.25; P = 0.008), 3-year PFS rate (HR: 1.24; 95% CI: 1.08 to 1.43; P = 0.002), 5-year OS rate (HR: 1.30; 95% CI, 1.09 to 1.55;P = 0.003), 5-year PFS rate (HR: 1.39; 95% CI, 1.14 to 1.70; P = 0.001) and ORR to chemotherapy (OR 1.66; 95% CI, 1.35 to 2.05; P < 0.001) of the patients in the Tax-PF group were statistically superior to those in the PF group. In terms of toxicities, the incidence of febrile neutropenia (OR 2.36; 95% CI, 1.62 to 3.46; P < 0.001), alopecia (OR 8.22; 95% CI, 3.99 to 16.92; P < 0.001), diarrhea (OR 1.57; 95% CI, 1.05 to 2.36; P = 0.03) and leukopenia (OR 2.79; 95% CI, 1.86 to 4.21; P < 0.001) was higher in the Tax-PF group.

Conclusion
The Tax-PF induction chemotherapy improved PFS and OS, and the ORR was better as compared to PF-based therapy regimens at the cost of a higher incidence of adverse events.
Proprotein convertase FURIN regulates T cell receptor-induced transactivation
Authors: Ortutay Zsuzsanna , Oksanen Anna , Aittomäki Saara , Ortutay Csaba , Pesu Marko 
Published: April 2015

Abstract
Antigen emergence rapidly stimulates T cells, which leads to changes in cytokine production, cell proliferation, and differentiation. Some of the key molecules involved in these events, such as TGF-β1 and NOTCH1, are synthesized initially as inactive precursors and are proteolytically activated during T cell activation. PCSKs regulate proprotein maturation by catalyzing the proteolytic cleavage of their substrates. The prototype PCSK FURIN is induced upon TCR activation, and its expression in T cells is critical for the maintenance of peripheral immune tolerance. In this study, we tested the hypothesis that FURIN regulates T cell activation. Our data demonstrate that IL-2 is increased initially in FURIN-deficient mouse CD4+ T cells, but the TCR-induced IL-2 mRNA expression is not sustained in the absence of FURIN. Accordingly, the inhibition of FURIN in human Jurkat T cell lines also results in a decrease in IL-2 production, whereas the overexpression of WT FURIN is associated with elevated IL-2 levels. In Jurkat cells, FURIN is dispensable for immediate TCR signaling steps, such as ERK, ZAP70, or LAT phosphorylation. However, with the use of gene reporter assays, we demonstrate that FURIN regulates the AP-1, NFAT, and NF-κB transcription factors. Finally, by performing a transcription factor-binding site enrichment analysis on FURIN-dependent transcriptomes, we identify the FURIN-regulated transcription factors in mouse CD4+ T cell subsets. Collectively, our work confirms the hypothesis that the TCR-regulated protease FURIN plays an important role in T cell activation and that it can specifically modulate TCR-activated transactivation.
Synthesis of Garnet-type Li7La3Zr2O12 by Coprecipitation Method
Authors: Hamao Naoki , Akimoto Junji 
Published: April 2015

Abstract
A tetragonal garnet-type Li7La3Zr2O12 sample was synthesized by the coprecipitation method for the first time. The particle morphology of the Li7La3Zr2O12 sample prepared by the coprecipitation method was elliptical shape and the primary grain size was smaller than the Li7La3Zr2O12 sample prepared by the conventional solid-state method. The result of the particle size distribution measurement shows that the average secondary particle size was approximately 9.66 µm, even after calcination at 950 °C with a relatively narrow distribution.
The occupation of art museum educator in the time of Occupy Museums
Authors: Kalin Nadine M. 
Published: April 2015

Abstract
This article considers the occupation of art museum educator in the time of Occupy Museums (OM). I maintain these two different forms of occupations – the job of educator as occupation within art museums and OM as an offshoot of the Occupy Wall Street (OWS) protests as occupation – are both related and at odds with one another in the context of the art museum under neo-liberal managerialism. The working lives of art museum educators are morphing into occupations within art institutions that employ populist veiling tactics as cover for labour abuse in fulfilling their missions. OM reveals contradictions inherent to a museum system working hard to normalize such economic injustices, with a particular focus on the workers associated with these institutions. Current trends in art museum education and features of OM are analysed through neo-liberalist and horizontalist ideologies, bringing to light similar anti-hierarchical motivations, aiming for dissimilar ends. The article closes with a call for a return to modified forms of verticality in institutions based on cultures of mutual support instead of capitalism alone.
The history of student radio in Poland
Authors: Doliwa Urszula 
Published: April 2015

Abstract
The earliest student radio stations in Poland were set up in the early 1950s. They broadcast as closed-circuit stations in student hostels and were accessible only by inhabitants of the campus. The level of freedom of speech at such stations was higher than in other types of media, not only because of special concessions with reference to students, but also because of a large number of such initiatives in Poland that were difficult to control. This type of student broadcasting lost a significant part of its audience in the early 1990s because of the development of the commercial radio sector. However, at the same time new possibilities for student broadcasting emerged. The Act on Radio and Television Broadcasting in 1992 introduced a new way of transmitting the signal – on air, with a licence. Contemporary student radio stations can be divided into two main groups: licensed and non-licensed (closed-circuit and Internet streaming). Between these two groups there are significant differences concerning organizational, financial and management issues, as well as the social functions they perform. Today, student radio is one of few mediums that broadcast spoken word programming and alternative music, as well as promoting participation, dialogue and marginalized voices.
Campus frequencies: ‘Alternativeness’ and Canadian campus radio
Authors: Fauteux Brian 
Published: April 2015

Abstract
Campus radio falls under the ‘community’ sector of Canada’s broadcasting system alongside the public and commercial sectors. Campus radio evokes a notion of ‘alternativeness’ in order to indicate its role as a sector rooted in a local community and to define its programming as distinct from other stations. This article uses Underground Sounds, a campus radio show broadcast by McGill University’s CKUT-FM, to explore the construction of ‘alternativeness’ in campus radio programming. This ten-week analysis of Underground Sounds took place in early 2008 and focuses on the artists and songs featured, the interviews conducted by the show’s host and on-air discussion of the show’s role in relation to the Montreal music scene. The findings highlight how ‘alternativeness’ is conveyed but also demonstrate its limitations and boundaries. For instance, new albums and upcoming concert dates factor into setting the limits of ‘alternativeness’, as being of current relevance significantly increases the chances that an artist is programmed. However, programmed artists are predominately represented by independent labels and are often local bands without much financial support. The goal of this article is to consider how ‘alternativeness’ might be conceptualized in relation to campus radio and the programming of ‘local’ and ‘independent’ music.
‘College radio’: The development of a trope in US student broadcasting
Authors: Rubin Nick 
Published: April 2015

Abstract
In the United States, the term ‘college radio’ invokes a specific, influential subset of student radio. In the early 1980s, ‘college radio’ appeared in popular discourse to refer to non-profit student stations which championed music marginalized by mainstream, commercial radio. College radio programming enacted a critique of the music industry’s political economy, reflecting participation in the late 1970s and early 1980s Do-It-Yourself (DIY) rock underground, an association of independent labels; independent record stores; small clubs; ‘zines; and those college stations which embraced punk and its offshoots. This subcultural identification carried tensions, namely, college stations functioned within the music industry they often sought to critique. As college radio communities negotiated this terrain, they helped shape ‘alternative’ and ‘indie’ culture – loosely defined but emblematic subsets of late twentieth-century US popular culture. Here, I examine the development and deployment of the ‘college radio’ signifier in the US public sphere, review the ­ existing academic literature on the sector and suggest avenues of future research.
The Winx Club phenomenon in the global animation landscape
Authors: Sigismondi Paolo 
Published: April 2015

Abstract
This article analyses the global rise of the Italian animated franchise the Winx Club (2004–) within the flows and contra-flows of entertainment content crossing the globe. A brain child of the entrepreneur Iginio Straffi, the Winx Club started out as a television series broadcasted in the Italian media landscape, and became a successful global entertainment franchise, distributed and licensed all over the world. The article situates this phenomenon in the evolving body of literature and scholarly conversations on media targeting children, their dynamics, industry practices, consequences and ramifications. In particular, the Winx Club appears to blend into the endless flow of images crossing national and cultural borders without providing images and specific cultural references drawn from the rich Italian cultural heritage, but trying instead to capture and fulfil the demand for entertainment of international children audiences proposing storylines not rooted in any specific culture, while being stylistically inspired by Japanese anime. This feature, combined with the application of successful business models practised for decades by the global leaders in the media industry, the US media conglomerates, appears to reveal the key to explicate the roots of the success of the Winx Club phenomenon in the competitive global media landscape targeting kids.
Comedy Neapolitan style: The cinema of Massimo Troisi
Authors: Puca Andrea 
Published: April 2015

Abstract
Neapolitan actor and director Massimo Troisi left behind an impressive body of work before his untimely death. Troisi’s final performance in Michael Radford’s Il Postino/The Postman (1994) was internationally acclaimed and earned him a Best Actor nomination at the 1996 Academy Awards. Still, Troisi’s films have received almost no attention from American film scholars and academics. The following article is thus an attempt to revive Troisi’s place in film history. Tracing the numerous influences presented in his films – from Commedia dell’Arte to the impact of Neapolitan actors Totò and Eduardo De Filippo – the article first contextualizes Troisi’s abundant, idiosyncratic use of dialect and gesture. This is followed by an examination of the impact of commedia all’italiana on the ideological orientation expressed by Troisi’s films. Ultimately, the concept of the comic ‘mask’ is used to define the uniquely Neapolitan, self-conscious personality Troisi crafted for his work as an actor and director.
Film Reviews
Authors: Nerenberg Ellen , Cristiano Anthony 
Published: April 2015

Abstract
Review of student films from the Scuola Nazionale and the University of Bologna, 2013
Experimentations in modern media into the twenty-first century and Bongiò’s Cilindro Raku: Numera Una and Backstage (Formazione Radial, 1AmuLtimediA 2007 – 10:34, and 14:30) – Bongiò; NUMERA Seconda and Backstage (1AmuLtimediA 2007 – HD 14:38, and 12:38) – Marcello Bongiò
Book Reviews
Authors: Marcus Millicent , Bondanella Peter , Orsitto Fulvio , Moura Pedro , Brown Shane , Deng MaoHui 
Published: April 2015

Abstract
Federico Fellini: Painting in Film, Painting on Film, Hava Aldouby (2013) Toronto: The University of Toronto Press, 186 pp., ISBN: 9781442613270, p/bk, $29.95
Sergio Leone: Il cinema come favola politica, Christian Uva (2013) Rome: Edizioni fondazione ente dello spettacolo, 220 pp., ISBN: 9788885095694, p/bk, €12.90
The Transatlantic Gaze. Italian Cinema, American Film, Mary Ann McDonald Carolan (2014) 1st ed., Albany: State University of New York, 172 pp., ISBN: 9781438450254, h/bk, $75.00
The Dragon and the Dazzle: Models, Strategies, and Identities of Japanese Imagination. A European Perspective, Marco Pellitteri (2012) Latina: Tunué, 670 pp., ISBN: 978889613894, p/bk, € 28.00
Masculinity and Italian Cinema. Sexual Politics, Social Conflict and Male Crisis in the 1970s, Sergio Rigoletto (2014) Edinburgh: Edinburgh University Press, 165 pp., ISBN: 9780748654543, h/bk, £65.00
Inspiring Fellini: Literary Collaborations behind the Scenes, Federico Pacchioni (2014) Toronto: University of Toronto Press, 256 pp., ISBN: 9781442612921, p/bk, $23.07