bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Doping Effects of Group‐IIIA Elements on Physical Properties of ZnMgXO (X: Al, Ga, In, Tl) Transparent Conducting Oxide Films Prepared by RF Magnetron Sputtering.
Authors: Jeong Sang‐Hun , Park Jang‐Ho , Lee Byung‐Teak 
Published: November 2014

AbstractZn0.88Mg0.1M0.02O (M: Al, Ga, In, Tl) films are grown on quartz by radio‐frequency magnetron sputtering using ceramic targets prepared by cold isostatic pressing and sintering of the respective metal oxide powders (950 °C, 6 h).
ChemInform Abstract: Crystalline Li3V6O16 Rods as High‐Capacity Anode Materials for Aqueous Rechargeable Lithium Batteries (ARLB).
Authors: Nair Vivek Sahadevan , Sreejith Sivaramapanicker , Borah Parijat , Hartung Steffen , Bucher Nicolas , Zhao Yanli , Madhavi Srinivasan 
Published: November 2014

AbstractLi3V6O16 rods are hydrothermally synthesized from aqueous mixtures of LiOAc and V2O5 (autoclave, 200 °C, 48 h), followed by heat treatment at 400 °C.
ChemInform Abstract: Polytopic Bis(oxazoline)‐Based Ligands for the Development of Recoverable Catalytic Systems Applied to the Cyclopropanation Reaction.
Authors: Garcia Jose I. , Garcia Jaime , Herrerias Clara I. , Mayoral Jose A. , Minana Ana C. , Saenz Carlos 
Published: November 2014

AbstractSeveral polytopic ligands are synthesized and tested in this model reaction.
ChemInform Abstract: N,N‐Dimethylaminobenzoates Enable Highly Enantioselective Sharpless Dihydroxylations of 1,1‐Disubstituted Alkenes.
Authors: Zhao Yaohong , Xing Xiangyou , Zhang Shaolong , Wang David Zhigang 
Published: November 2014

AbstractThe N,N‐dimethylaminobenzoate moiety is found to be an efficient auxiliary for inducing high levels of enantioselectivity in the dihydroxylation of the challenging substrate class of 1,1‐disubstituted aliphatic alkenes (I) and (III).
ChemInform Abstract: Enantioselective Cascade Formal Reductive Insertion of Allylic Alcohols into the C(O)—C Bond of 1,3‐Diketones: Ready Access to Synthetically Valuable 3‐Alkylpentanol Units.
Authors: Roudier Mylene , Constantieux Thierry , Quintard Adrien , Rodriguez Jean 
Published: November 2014

AbstractFunctionalized γ‐chiral alcohols are prepared via an unprecedented cascade reaction which combines dual iron—amine‐catalyzed enantioselective functionalization of allylic alcohols and chemoselective acyl transfer.
ChemInform Abstract: Introducing Deep Eutectic Solvents to Polar Organometallic Chemistry: Chemoselective Addition of Organolithium and Grignard Reagents to Ketones in Air.
Authors: Vidal Cristian , Garcia‐Alvarez Joaquin , Hernan‐Gomez Alberto , Kennedy Alan R. , Hevia Eva 
Published: November 2014

AbstractCommercial solutions of metal organyls either in THF, hexanes or Bu2O are used in these reactions.
ChemInform Abstract: PhICl2‐Mediated Conversion of Enamines into α,N‐Dichloroimines and Their Reverse Conversion Mediated by Zinc in Methanol.
Authors: Tang Linlin , Zhang‐Negrerie Daisy , Du Yunfei , Zhao Kang 
Published: November 2014

AbstractA novel method for the synthesis of α,N‐dichloroimines through chlorination of enamines with PhICl2 as chlorine source is presented.
ChemInform Abstract: Simple and Efficient Method for the Protection of Hydroxyl Groups as 4‐Methoxybenzyl Ethers.
Authors: Kasprzycka Anna , Ptaszek‐Budniok Agata , Szeja Wieslaw 
Published: November 2014

Abstract4‐Methoxybenzyl N‐allyl thiocarbamate (III) prepared from 4‐methoxybenzyl alcohol (I) and N‐allylisothiocyanate (II) is shown to be a suitable reagent to introduce the 4‐methoxybenzyl protecting group to various alcohols.
ChemInform Abstract: Room‐Temperature Hydrohydrazination of Terminal Alkynes Catalyzed by Saturated Abnormal N‐Heterocyclic Carbene—Gold(I) Complexes.
Authors: Manzano Ruben , Wurm Thomas , Rominger Frank , Hashmi A. Stephen K. 
Published: November 2014

AbstractA combination of a saturated abnormal N‐goldheterocyclic carbene complex with KBARF as activator, is successfully applied in the chemoselective addition of hydrazine to alkynes.
ChemInform Abstract: CuI Catalyzed Sulfonylation of Organozinc Reagents with Sulfonyl Halides.
Authors: Fu Ying , Zhu Wenbo , Zhao Xingling , Huegel Helmut , Wu Zhouqiang , Su Yuhu , Du Zhengyin , Huang Danfeng , Hu Yulai 
Published: November 2014

AbstractThe title reaction provides access to a series of alkyl, aryl and hetaryl sulfones (III) and (V) bearing various kinds of functional groups.
ChemInform Abstract: Synthesis of 2‐(2‐Fluorophenyl)‐2‐methylamino‐cyclohexanone as a New Ketamine Derivative.
Authors: Moghimi Abolghasem , Rahmani Siyavash , Zare Reza , Sadeghzadeh Morteza 
Published: November 2014

AbstractA four‐step synthetic method for the synthesis of the title compound (VII) involving a Pd‐catalyzed rearrangement as the key step is presented.
ChemInform Abstract: Silver‐Catalyzed Decarboxylative Acylfluorination of Styrenes in Aqueous Media.
Authors: Wang Hua , Guo Li‐Na , Duan Xin‐Hua 
Published: November 2014

AbstractOnly trace amounts of products were obtained from the reaction of 2‐methyl phenylglyoxylic acid or 1‐naphthyloxoacetic acid with (II).
ChemInform Abstract: Singlet Oxygen‐Mediated Synthesis of Bis‐spiroketals Found in Azaspiracids.
Authors: Triantafyllakis Myron , Tofi Maria , Montagnon Tamsyn , Kouridaki Antonia , Vassilikogiannakis Georgios 
Published: November 2014

AbstractConversion of a simple furan into the ABCD‐ring skeleton of the azaspiracids via a singlet oxygen‐initiated one‐pot process is described.
ChemInform Abstract: A New Approach for the Synthesis of N‐Sulfonyl Hydantoins.
Authors: Rmedi Hamdi , Baklouti Ahmed 
Published: November 2014

AbstractThe triethylamine mediated reaction of α‐bromoacetamides with N‐sulfonyl isocyanates gives urea salts which undergo intramolecular cyclization to N‐sulfonyl hydantoins under thermal conditions.
ChemInform Abstract: Facile Synthesis of Fluorescent Active Triazapentalenes Through Gold‐Catalyzed Triazole—Alkyne Cyclization.
Authors: Cai Rong , Wang Dawei , Chen Yunfeng , Yan Wuming , Geise Natalie R. , Sharma Sripadh , Li Huiyuan , Petersen Jeffrey L. , Li Minyong , Shi Xiaodong 
Published: November 2014

AbstractThe products exhibit significantly improved stabilities compared to monosubstituted triazapentalene zwitterions.
ChemInform Abstract: [C16MPy]AlCl3Br: An Efficient Novel Ionic Liquid for Synthesis of Novel 1,2,4‐Triazolidine‐3‐thiones in Water.
Authors: Patil Jayavant D. , Pore Dattaprasad M. 
Published: November 2014

AbstractThe applied catalyst is prepared in two steps from N‐methyl pyrrolidine.
ChemInform Abstract: Visible‐Light‐Mediated Fluoroalkylation of Isocyanides with Ethyl Bromofluoroacetates: Unified Synthesis of Mono‐ and Difluoromethylated Phenanthridine Derivatives.
Authors: Sun Xiaoyang , Yu Shouyun 
Published: November 2014

AbstractA visible‐light promoted alkylation, followed by decarboxylation starting from biphenyl isocyanides with acetates (II) or (V) gives access to the title species (IV) and (VII) in a stepwise or a one‐pot manner.
ChemInform Abstract: Catalyst‐Controlled Regio‐ and Stereoselective Synthesis of Diverse 12H‐6,12‐Methanodibenzo[d,g][1,3]dioxocines.
Authors: Xia Likai , Cai Hongyun , Lee Yong Rok 
Published: November 2014

AbstractTitle compounds (III), (VI), and (VII) are prepared via ethylenediammonium diacetate or TosOH‐catalyzed cascade reactions between resorcinols (I) and (IV) and 2‐hydroxychalcones (II) and (V), respectively.
ChemInform Abstract: A Versatile Synthesis of “Tafuramycin A”: A Potent Anticancer and Parasite Attenuating Agent.
Authors: El‐Deeb Ibrahim M. , Rose Faith J. , Healy Peter C. , von Itzstein Mark 
Published: November 2014

AbstractThe improved synthesis of tafuramycin A (I) includes a regioselective bromination step, a controlled aryl radical alkene cyclization to prevent dechlorination, and a new protection/deprotection method to avoid double bond reduction of the furan ring during deprotection of the benzyl group.
ChemInform Abstract: Self‐Assembly of Magnetite Nanocubes into Helical Superstructures.
Authors: Singh Gurvinder , Chan Henry , Baskin Artem , Gelman Elijah , Repnin Nikita , Kral Petr , Klajn Rafal 
Published: November 2014

AbstractCubic nanocrystals of magnetite self‐assemble into arrays of helical superstructures in a template‐free manner with <99% yield by placing a drop of hexane solution of magnetite nanocubes containing excess oleic acid at the interface of diethylene glycol—air in the presence of an external magnetic field, followed by evaporation of the solvent.
High CerS5 expression levels associate with reduced patient survival and transition from apoptotic to autophagy signalling pathways in colorectal cancer
Authors: Fitzgerald Seán , Sheehan Katherine M , Espina Virginia , O'Grady Anthony , Cummins Robert , Kenny Dermot , Liotta Lance , O'Kennedy Richard , Kay Elaine W , Kijanka Gregor S 
Published: November 2014

AbstractCeramide synthase 5 is involved in thede novosynthesis of ceramide, a sphingolipid involved in cell death and proliferation. In this study, we investigated the role of ceramide synthase 5 in colorectal cancer by examining ceramide synthase 5 expression, clinico‐pathological parameters and association with survival/death signalling pathways in cancer. Immunohistochemical analysis of CerS5 was performed on 102 colorectal cancer samples using tissue microarrays constructed from formalin‐fixed and paraffin‐embedded tissues. We found strong membranous ceramide synthase 5 staining in 57 of 102 (56%) colorectal cancers. A multivariate Cox regression analysis of ceramide synthase 5 expression adjusted for disease stage, differentiation and lymphovascular invasion revealed reduced 5‐year overall survival (p = 0.001) and 5‐year recurrence‐free survival (p = 0.002), with hazard ratios of 4.712 and 4.322, respectively. The effect of ceramide synthase 5 expression on tumourigenic processes was further characterised by reverse phase protein array analysis. Reverse phase protein arrays were generated from laser capture microdissection‐enriched carcinoma cells from 19 fresh‐frozen colorectal cancer tissues. Measurements of phosphorylation and total levels of signalling proteins involved in apoptosis, autophagy and other cancer‐related pathways revealed two distinct signalling networks; weak membranous ceramide synthase 5 intensity was associated with a proteomic network dominated by signalling proteins linked to apoptosis, whereas strong ceramide synthase 5 intensity was associated with a proteomic sub‐network mostly composed of proteins linked to autophagy. In conclusion, high ceramide synthase 5 expression was found in colorectal cancer tissue and was associated with poorer patient outcomes. Our findings suggest that this may be mediated by a transition from apoptotic to autophagy signalling pathways in ceramide synthase 5 High expressing tumours, thus implicating ceramide synthase 5 in the progression of colorectal cancer.
Aspherical‐Atom Modeling of Coordination Compounds by Single‐Crystal X‐ray Diffraction Allows the Correct Metal Atom To Be Identified
Authors: Dittrich Birger , Wandtke Claudia M. , Meents Alke , Pröpper Kevin , Mondal Kartik Chandra , Samuel Prinson P. , Amin SK Nurul , Singh Amit Pratap , Roesky Herbert W. , Sidhu Navdeep 
Published: November 2014

AbstractSingle‐crystal X‐ray diffraction (XRD) is often considered the gold standard in analytical chemistry, as it allows element identification as well as determination of atom connectivity and the solid‐state structure of completely unknown samples. Element assignment is based on the number of electrons of an atom, so that a distinction of neighboring heavier elements in the periodic table by XRD is often difficult. A computationally efficient procedure for aspherical‐atom least‐squares refinement of conventional diffraction data of organometallic compounds is proposed. The iterative procedure is conceptually similar to Hirshfeld‐atom refinement (Acta Crystallogr. Sect. A­ 2008, 64, 383–393; IUCrJ. 2014, 1,61–79), but it relies on tabulated invariom scattering factors (Acta Crystallogr. Sect. B­ 2013, 69, 91–104) and the Hansen/Coppens multipole model; disordered structures can be handled as well. Five linear‐coordinate 3d metal complexes, for which the wrong element is found if standard independent‐atom model scattering factors are relied upon, are studied, and it is shown that only aspherical‐atom scattering factors allow a reliable assignment. The influence of anomalous dispersion in identifying the correct element is investigated and discussed.
Superior Ion‐Conducting Hybrid Solid Electrolyte for All‐Solid‐State Batteries
Authors: Kim Jae‐Kwang , Scheers Johan , Park Tae Joo , Kim Youngsik 
Published: November 2014

AbstractHerein, we developed a high‐performance lithium ion conducting hybrid solid electrolyte, consisted of LiTFSI salt, Py14TFSI ionic liquid, and TiO2 nanoparticles. The hybrid solid electrolyte prepared by a facile method had high room temperature ionic conductivity, excellent thermal stability and low interface resistance with good contact. In addition, the lithium transference number was highly increased by the scavenger effect of TiO2 nanoparticles. With the hybrid solid electrolyte, the pouch‐type solid‐state battery exhibited high initial discharge capacity of 150 mA h g−1 at room temperature, and even at 1 C, the reversible capacity was as high as 106 mA h g−1.
Tuning the Morphology of GeS2 Hybrid Materials Using Ionic Liquids as Structuring Agents
Authors: Mathiaud Romain , Courthéoux Laurence , Silly Gilles , Albadri Hashim , Levillain Jocelyne , Gaumont Annie‐Claude , Ribes Michel , Pradel Annie 
Published: November 2014

AbstractControl of the surface chemistry and morphology of chalcogenide materials, which are highly polarizable, is a very interesting challenge as it might lead to breakthroughs in various fields such as electrochemistry, catalysis, and gas‐phase separation. With this in mind, a new approach to synthesize structured Ge‐based chalcogenide products has been investigated. It involves the use of tetraethoxygermanium (TEOG) and thioacetamide with an ionic liquid (IL) as structuring agent. This innovative synthesis process has two main advantages: it is performed under soft conditions, and it also enables the morphological control of the obtained hybrid organic–GeS2 particles. In the absence of the IL, the synthesis leads to an agglomeration of nanospheres, whereas the introduction of the ionic liquid leads either to microspheres or to gypsum rosette‐like particles. It has been clearly highlighted that the morphology of the hybrid organic–GeS2 particles strongly depended on the nature of the cationic part of the IL.
Silver nanoparticle toxicity to Atlantic killifish (Fundulus heteroclitus) and Caenorhabditis elegans: A comparison of mesocosm, microcosm, and conventional laboratory studies
Authors: Bone Audrey J. , Matson Cole W. , Colman Benjamin P. , Yang Xinyu , Meyer Joel N. , Di Giulio Richard T. 
Published: November 2014

Abstract

The use of silver nanoparticles (AgNPs) in consumer products and industrial applications, as well as their recent detection in waste streams, has created concern about potential impacts on aquatic ecosystems. The effect of complex environmental media on AgNP toxicity was investigated using wetland mesocosms and smaller scale microcosms. Mesocosms were dosed with 2.5 mg Ag/L as gum arabic (GA)-coated AgNPs, polyvinylpyrrolidone (PVP)-coated AgNPs, or AgNO3. Water samples were taken from mesocosms 24 h after dosing for acute toxicity tests with embryos and larvae of Atlantic killifish (Fundulus heteroclitus) and the nematode Caenorhabditis elegans. Acute toxicity tests were also performed on Atlantic killifish with AgNO3, GA AgNPs, and PVP AgNPs prepared in the laboratory with similar water. For killifish embryos, mesocosm samples were much less toxic than laboratory samples for all types of silver. For larvae, in contrast, all 3 silver mesocosm treatments exhibited toxicity. Interestingly, mesocosm samples of AgNO3 were less toxic than laboratory samples; samples containing GA AgNPs were similar in toxicity, and samples containing PVP AgNPs were more toxic. For C. elegans, results were similar to killifish larvae. Results obtained from the mesocosms were not replicated on the smaller scale of the microcosms. These results indicate that environmental factors unique to the mesocosms acted differentially on AgNO3 to reduce its toxicity in a manner that does not translate to AgNPs for larval fish. Environ Toxicol Chem 2014;9999:1–9. © 2014 SETAC
A mixture of environmental organic contaminants in lake sediments affects hatching from Daphnia resting eggs
Authors: Möst Markus , Chiaia-Hernandez Aurea C. , Frey Martin P. , Hollender Juliane , Spaak Piet 
Published: November 2014

Abstract

Despite the relevance of resting eggs for ecology and evolution of many aquatic organisms and their exposure to contaminants accumulating in sediments, ecotoxicological studies using resting eggs are vastly underrepresented. The authors established a method to perform exposure assays with resting eggs produced by the Daphnia longispina species complex, key species in large lake ecosystems. A mixture of organic contaminants previously detected in sediments of Lake Greifensee was selected to test the potential effect of organic contaminants present in sediments on the hatching process. Resting eggs were exposed to a mix of 10 chemicals, which included corrosion inhibitors, biocides, pesticides, and personal care products, for a period of 15 d. Using an automated counting software, the authors found a significant increase in hatching success in the exposed resting eggs compared with controls. Such an effect has not yet been reported from ecotoxicological assays with resting eggs. Possible mechanistic explanations as well as the potential implications on the ecology and evolution of aquatic species that rely on a resting egg banks are discussed. Observed increased mortality and developmental abnormalities for hatchlings in the exposure treatments can be explained by toxic contaminant concentrations. The results of the present study highlight the need for additional studies assessing the effects of organic contaminants on resting egg banks and aquatic ecosystems. Environ Toxicol Chem 2014;9999:1–8. © 2014 SETAC
Combustion properties of Brazilian natural wood species
Authors: de Freitas Rocha Monique Amaro , Landesmann Alexandre 
Published: November 2014

SummaryThis paper investigates the combustion characteristics of 12 wood species natural to Brazil. A mass loss cone calorimeter was used to obtain the properties associated with (i) heat release rate (HRR), peak HRR, and total heat released; (ii) total mass loss and mass loss rate; (iii) average effective heat of combustion; and (iv) time to ignition, time of pyrolysis and temperature of ignition. The samples used in this work were as follows: (i) prepared in accordance to ISO 5660‐1:2002; (ii) oven dried; (iii) irradiated with a constant heat flux of 50 kW/m2; and (iv) exhibit wood fiber orientation in a plane orthogonal to the flux incidence. Finally, the paper explores the possibility of linking the obtained combustion properties with the density and classes of selected wood species. Copyright © 2014 John Wiley & Sons, Ltd.
Reproducible Simulations of Realistic Samples for Next‐Generation Sequencing Studies Using Variant Simulation Tools
Authors: Peng Bo 
Published: November 2014

ABSTRACTComputer simulations have been widely used to validate and evaluate the power of statistical methods for genetic epidemiological studies. Although a large number of simulation methods and software packages have been developed for genome‐wide association studies, methodological and bioinformatics challenges have limited their applications in simulating datasets for whole‐genome and whole‐exome sequencing studies. With the development of more sophisticated statistical methods that make fuller use of available data and our knowledge of the human genome, there is a pressing need for genetic simulators that capture more features of empirical data (e.g., multiallele variants, indels, use of the Variant Call Format) and the human genome (e.g., functional annotations of genetic variants). This article introduces Variant Simulation Tools (VST), a module of Variant Tools for the simulation of genetic variants for sequencing‐based genetic epidemiological studies. Although multiple simulation engines are provided, the core of VST is a novel forward‐time simulation engine that simulates real nucleotide sequences of the human genome using DNA mutation models, fine‐scale recombination maps, and a selection model based on amino acid changes of translated protein sequences. The design of VST allows users to easily create and distribute simulation methods and simulated datasets for a variety of applications and encourages fair comparison between statistical methods through the use of existing or reproduced simulated datasets.
Changes in corticostriatal connectivity during reinforcement learning in humans
Authors: Horga Guillermo , Maia Tiago V. , Marsh Rachel , Hao Xuejun , Xu Dongrong , Duan Yunsuo , Tau Gregory Z. , Graniello Barbara , Wang Zhishun , Kangarlu Alayar , Martinez Diana , Packard Mark G. , Peterson Bradley S. 
Published: November 2014

AbstractMany computational models assume that reinforcement learning relies on changes in synaptic efficacy between cortical regions representing stimuli and striatal regions involved in response selection, but this assumption has thus far lacked empirical support in humans. We recorded hemodynamic signals with fMRI while participants navigated a virtual maze to find hidden rewards. We fitted a reinforcement‐learning algorithm to participants' choice behavior and evaluated the neural activity and the changes in functional connectivity related to trial‐by‐trial learning variables. Activity in the posterior putamen during choice periods increased progressively during learning. Furthermore, the functional connections between the sensorimotor cortex and the posterior putamen strengthened progressively as participants learned the task. These changes in corticostriatal connectivity differentiated participants who learned the task from those who did not. These findings provide a direct link between changes in corticostriatal connectivity and learning, thereby supporting a central assumption common to several computational models of reinforcement learning. Hum Brain Mapp 36:793–803, 2015. © 2014 Wiley Periodicals, Inc.