bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multigene phylogenetic study of Cyclaneusma species
Authors: Prihatini I. , Glen M. , Wardlaw T. J. , Mohammed C. L. 
Published: March 2014

SummaryCyclaneusma Needle Cast is associated with the fungal pathogen Cyclaneusma minus. The disease has led to significant losses of Pinus radiata production in New Zealand, but the disease appears less serious in Australia. Two cultural morphotypes of C. minus have been discriminated in New Zealand, and isolates from Australia also correspond to these two morphotypes. To examine if the two morphotypes of Cyclaneusma are different species, phylogenetic analysis using sequences from five gene regions (rDNA ITS, mt‐LSU, n‐LSU, tef–1 and βT‐1) was conducted. This study revealed that C. minus consists of two distinct clades which correspond to the two morphotypes. One morphotype (‘verum’) was more closely related to Cyclaneusma niveum than to the other morphotype (‘simile’). A morphological description is required to formalise the new species represented by the ‘simile’ clade; an investigation of the individual pathogenic behaviours of both morphotypes is also required.
The effects of traffic light labels and involvement on consumer choices for food and financial products
Authors: Drescher Larissa S. , Roosen Jutta , Marette Stéphan 
Published: March 2014

AbstractTraffic light (TL) labels that inform consumers regarding product safety have received increasing attention in different fields. Behind the background of behavioural economics, this paper presents the results of a split‐sample choice experiment conducted in Germany to evaluate the impact of TL labelling on purchases of food and financial products. We hypothesize that consumers experience different levels of involvement with these two types of products, leading to different recommendations regarding the use of TLs. The results show that TLs affect consumer purchases of both product groups by focusing their attention on specific product attributes. For food, whereas the low‐fat attribute has no significant impact on food choices that do not include TLs, this attribute has a positive impact on choices once it is signalled with a TL label. The positive evaluation of the organic production attribute of a food product without a TL decreases when the same product is labelled with a TL. In the case of financial products, TLs significantly reinforce the impact of all characteristics on choice probability. TLs also generate a halo effect with regard to return variance. Although consumers demonstrate different levels of involvement for the two types of products, involvement does not always impact the evaluation of attributes. Compared with less involved consumers, more involved consumers exhibit more heterogeneous evaluations of the return variability attribute in the case of the financial product and the organic attribute in the case of the food product.
Costs, culture and life decisions: analysing the factors that influence enrolment in master's level education in Germany
Authors: Silvester Danielle , Loibl Cäzilia , Roosen Jutta 
Published: March 2014

AbstractThrough evaluation of current literature and survey data, this exploratory study aimed to determine factors that influence enrolment in master's level education and attendant delay of life decisions. A total of 134 master's students at a German university were surveyed. The mean age was 25 years and respondents were nearly equal parts German and non‐German nationalities. Results show how cultural factors motivate enrolment in master's programmes and how enrolment influences the timing of other important life decisions. Respondents expected significant benefits to social status, job placement and income. While this small‐scale study does not include all decision factors and its findings are not fully generalizable, we hope it motivates further research in this area.
Modulation of sebum oxidation and interleukin‐1α levels associates with clinical improvement of mild comedonal acne
Authors: Capitanio B. , Lora V. , Ludovici M. , Sinagra J.‐L. , Ottaviani M. , Mastrofrancesco A. , Ardigò M. , Camera E. 
Published: March 2014

AbstractBackgroundSebum plays a key role in the initiation of the acne lesions. Oxidized sebum lipids cause keratynocytes hyperproliferation and inflammatory cytokines release. Association between sebum oxidation and comedogenesis has been little investigated in comedonal acne.ObjectivesEvaluation of sebum oxidation parameters and levels of inflammatory cytokines (IL‐1α) in patients with mild comedonal acne (MCA) before and after the treatment with a mixed RetinSphere®‐ vitamin E formulation.MethodsSebum excretion rate (SER), squalene concentration, and oxidation degree of sebum were measured in 18MCApatients and 10 controls.IL‐1α levels in the stratum corneum were measured in both lesional and non‐lesional facial areas ofMCApatients. Sebum parameters andIL‐1α were measured at week 4 of topical treatment. Reflectance confocal microscopy (RCM) was performed in a subset of four patients at the baseline and at week 4 and all patients were assessed clinically before and following the 8 week‐treatment.ResultsSebum excretion rate and squalene concentration were comparable betweenMCApatients and healthy controls. Lipid peroxidation (LPO) and the percentage of oxidized squalene (SQOX) were significantly elevated in the sebum ofMCApatients. The concentration of the proinflammatory cytokineIL‐1α in stratum corneum was significantly higher in the lesional area compared with non‐lesional area of theMCApatients at the baseline. At week 4, whileSERand squalene concentration did not vary significantly, theLPOlevels and theSQOXpercentage resulted decreased at a significant extent. Following the treatment,IL‐1α concentration in the lesional area reached values comparable to those of unaffected areas. Consistent with the biochemical data,RCMshowed the reduction of hyperkeratinization and of inflammatory cells infiltration of the adnexal structures epithelium, significant clinical improvement was recorded at week 8.ConclusionThe data further support the involvement of lipid oxidation and particularly by‐products of squalene oxidation in comedogenesis.
Relationship between the IL‐4 gene promoter ‐590C/T (rs2243250) polymorphism and susceptibility to autoimmune diseases: a meta‐analysis
Authors: Qiu L.‐J. , Ni J. , Cen H. , Wen P.‐F. , Zhang M. , Liang Y. , Pan H.‐F. , Mao C. , Ye D.‐Q. 
Published: March 2014

AbstractObjectiveStudies investigating the association between interleukin (IL)‐4 gene promoter ‐590C/T (rs2243250) polymorphism and autoimmune diseases report conflicting results. To derive a more precise estimation of the relationship, a meta‐analysis was performed.MethodsA systematic literature search was conducted to identify relevant studies. Pooled odds ratio (OR) with 95% confidence interval (CI) was used to estimate the strength of association.ResultsA total of 6001 cases and 6788 controls from 24 studies were analysed. Significant association of the C allele of IL‐4 rs2243250 polymorphism with rheumatoid arthritis (RA) was detected (odds ratio (OR) = 0.696, 95% confidence interval (CI) = 0.601–0.807). Stratification by ethnicity indicated an association between the IL‐4 rs2243250 polymorphism and RA in Caucasians. Furthermore, the overall ORs of the associations between the C allele and multiple scleorosis (MS) were 1.340 (95% CI = 1.102–1.630). However, we failed to reveal any association between IL‐4 rs2243250 polymorphism and systemic lupus erythematosus (SLE), type 1 diabetes (T1D) or Graves' disease (GD).ConclusionsThe present study suggests that the IL‐4 rs2243250 polymorphism might be associated with genetic susceptibility to autoimmune diseases, including RA and MS.
Loss‐of‐function mutations in the gene encoding filaggrin underlie a Japanese family with food‐dependent exercise‐induced anaphylaxis
Authors: Mizuno O. , Nomura T. , Ohguchi Y. , Suzuki S. , Nomura Y. , Hamade Y. , Hoshina D. , Sandilands A. , Akiyama M. , McLean W.H.I. , Abe R. , Shimizu H. 
Published: March 2014

AbstractBackgroundFood‐dependent exercise‐induced anaphylaxis (FDEIA) is a serious food allergy in which anaphylaxis develops when exercise is performed within several hours after food intake. The precise mechanism underlying allergic sensitization in FDEIA has been an important issue but remains poorly understood.ObjectivesWe aimed to elucidate the pathomechanism including the route of allergen sensitization involved in FDEIA.MethodsA Japanese family with wheat‐dependent exercise‐induced anaphylaxis (WDEIA), a specific form of FDEIA, were clinically examined. Mutation analysis of the gene encoding filaggrin (FLG) was also performed.ResultsTwo of the family members were confirmed as WDEIA on the basis of their medical history and positive provocation test results. Notably, the two affected individuals in the family had concomitant ichthyosis vulgaris. Mutation analysis of FLG revealed that they carry one or more loss‐of‐function mutations that have not been described in the Japanese population.ConclusionThese results indicate that FLG mutations might be involved in the pathogenesis of WDEIA in the present case.
PAS‐positive extracellular deposits within germinal centers of hyperplastic follicles during SIV infection in a rhesus macaque
Authors: Hong Jung Joo , Villinger Francois , Courtney Cynthia L 
Published: March 2014

AbstractBackgroundLymphoid tissue remodeling is characteristic of chronic simian immunodeficiency virus infection.MethodsA rhesus macaque infected with SIVmac239 was necropsied and its lymphoid tissues subjected to histopathology characterization.ResultsGerminal centers in spleen and lymph nodes contained PAS‐positive, non‐amyloid extracellular deposits, decreased T follicular helper cells, and normal density of Ki67+ B cells.ConclusionsA possible mechanism for PAS‐positive deposits includes exaggerated involution of SIV‐induced follicular hyperplasia secondary to virus‐associated immune reaction.
The Role of Previous Contraception Education and Moral Judgment in Contraceptive Use
Authors: Bader Valerie , Kelly Patricia J. , Cheng An‐Lin , Witt Jackie 
Published: March 2014

IntroductionThe knowledge and attitudes that lead to nonuse of contraception are not well understood. The goal of this study was to determine whether an association exists between contraceptive use and specific knowledge and attitudinal factors.MethodsWe conducted a secondary analysis of data from a nationally representative telephone survey of 897 unmarried women aged 18 to 29 years to examine the relationship between contraceptive use and comprehensive sex education, attitude toward pregnancy prevention, perceived infertility, distrust toward the health care system or contraception, and moral attitude toward contraception.ResultsBoth ever having made a visit to a physician or clinic for women's health care and ever having used any method of contraception to prevent pregnancy were significantly impacted by more comprehensive sex education and less likelihood to view contraception as morally wrong. Consistent with other research, we found no association between the desire to avoid pregnancy and contraceptive use. We found an association between health system distrust and contraceptive use, but health system distrust did not predict contraceptive use.DiscussionOur findings show that contraceptive use among a sample of young women is influenced by previous contraceptive education and moral attitudes toward contraception. Clinicians should be cognizant of these realities, which may need to be addressed in both clinical and nonclinical venues.
Discontinuation of Dual Antiplatelet Therapy Over 12 Months after Acute Coronary Syndromes Increases Risk for Adverse Events in Patients Treated with Percutaneous Coronary Intervention: Systematic Review and Meta‐Analysis
Authors: D'ASCENZO FABRIZIO , COLOMBO FRANCESCO , BARBERO UMBERTO , MORETTI CLAUDIO , OMEDÈ PIERLUIGI , REED MATTHEW J. , TARANTINI GIUSEPPE , FRATI GIACOMO , DI NICOLANTONIO JAMES J. , BIONDI ZOCCAI GIUSEPPE , GAITA FIORENZO 
Published: March 2014

IntroductionDuration of dual antiplatelet therapy (DAPT) following acute coronary syndrome (ACS) hospitalization remains to be defined, both for patients treated medically and for those undergoing percutaneous transluminal coronary angioplasty (PTCA).MethodsPubMed, Cochrane, and Google Scholar were systematically searched for studies including patients presenting with ACS, and treated either with DAPT longer than or shorter than 12 months. Multivariable‐adjusted risk estimates for death and recurrent ACS with stopping DAPT after 12 months (odds ratios [OR] 95% confidence intervals [CI]) were pooled after logarithmic transformation according to random‐effect models with inverse‐variance weighting.ResultsFive studies with 49,586 patients were included. Median age was 66 (64–67) years, with 67% (65–75) males. Myocardial infarction (MI) represented the admission diagnosis for 88% (60–100) of the patients, and 66% (50–74) were treated with stenting. After a follow‐up of 2.1 years (1.5–2.7), 40% (35–46) still on DAPT after 12 months and the rates of death or recurrent ACS were 16.6 (14.5–17.0). Risk of adverse events for patients stopping DAPT after 1 year was significantly increased (OR = 1.19 [1.07–1.32]) for those receiving stents, but not for patients managed medically (OR = 1.13 [0.95–1.35]). The increased risk did not vary according to age, gender, myocardial infarction as admission diagnosis, and kind of stent.ConclusionsInterruption of DAPT over 12 months after ACS increases the risk of adverse events for patients treated with PTCA, but not for those managed conservatively, independently from baseline features and admission diagnosis. This hypothesis‐generating finding should be tested in randomized controlled trials. (J Interven Cardiol 2014;27:233–241)
MODELLING FOR THE WAVELET COEFFICIENTS OF ARFIMA PROCESSES
Authors: Nanamiya Kei 
Published: March 2014

AbstractWe consider a model for the discrete nonboundary wavelet coefficients of autoregressive fractionally integrated moving average (ARFIMA) processes in each scale. Because the utility of the wavelet transform for the long‐range dependent processes, which many authors have explained in semi‐parametrical literature, is approximating the transformed processes to white noise processes in each scale, there have been few studies in a parametric setting. In this article, we propose the model from the forms of the (generalized) spectral density functions (SDFs) of these coefficients. Since the discrete wavelet transform has the property of downsampling, we cannot directly represent these (generalized) SDFs. To overcome this problem, we define the discrete non‐decimated nonboundary wavelet coefficients and compute their (generalized) SDFs. Using these functions and restricting the wavelet filters to the Daubechies wavelets and least asymmetric filters, we make the (generalized) SDFs of the discrete nonboundary wavelet coefficients of ARFIMA processes in each scale clear. Additionally, we propose a model for the discrete nonboundary scaling coefficients in each scale.
Relationship among Serum Creatinine, Serum Gastrin, Calcium‐phosphorus Product, and Uremic Gastropathy in Cats with Chronic Kidney Disease
Authors: McLeland S.M. , Lunn K.F. , Duncan C.G. , Refsal K.R. , Quimby J.M. 
Published: March 2014

BackgroundChronic kidney disease (CKD) in cats is associated with gastrointestinal signs commonly attributed to uremic gastropathy. Consequently, patients often are treated with antacids and gastrointestinal protectants. This therapeutic regimen is based on documented gastric lesions in uremic humans and dogs, but the nature and incidence of uremic gastropathy in cats are unknown.Hypothesis/ObjectivesEvaluate uremic gastropathy inCKDcats to facilitate refinement of medical management for gastrointestinal signs.AnimalsThirty‐seven CKD cats; 12 nonazotemic catsMethodsStomachs were evaluated for the presence of classic uremic gastropathy lesions. Histopathologic lesions were compared with serum creatinine concentrations, calcium‐phosphorus product (CPP), and serum gastrin concentrations.ResultsGastric ulceration, edema, and vascular fibrinoid change were not observed. The most important gastric lesions inCKDcats were fibrosis and mineralization. SixteenCKDcats (43%) had evidence of gastric fibrosis of varying severity and 14CKDcats (38%) had gastric mineralization.CKDcats were more likely to have gastric fibrosis and mineralization than nonazotemic controls (P = .005 andP = .021, respectively). Only cats with moderate and severe azotemia had gastric mineralization.CPPwas correlated with disease severity; severely azotemicCKDcats had significantly higherCPPwhen compared with nonazotemic controls, and to mildly and moderately azotemic cats (P < .05). Gastrin concentrations were significantly higher inCKDcats when compared with nonazotemic controls (P = .003), but increased concentrations were not associated with gastric ulceration.Conclusions and Clinical ImportanceUremic gastropathy inCKDcats differs from that described in other species and this difference should be considered when devising medical management.
A prospective observational study on tolerance and satisfaction to hepatic haemodynamic procedures
Authors: Casu Stefania , Berzigotti Annalisa , Abraldes Juan G. , Baringo M. Angels , Rocabert Laura , Hernández‐Gea Virginia , García‐Pagán Joan Carles , Bosch Jaume 
Published: March 2014

AbstractBackgroundUnderstanding patients' attitudes to clinical experiences is essential for developing high‐quality patient‐centred healthcare, as a better knowledge of patients' tolerance and satisfaction might allow implementing measures that ameliorate comfort, care and use of resources.AimsWe aimed to describe patients' tolerance and satisfaction to invasive hepatic haemodynamic procedures, and to investigate which factors might influence patients' perspective in this field.MethodsVisual Analogue Scale (VAS) questionnaires regarding pain and duration (for tolerance), and comfort and general handling (for satisfaction) were prospectively administered to all consecutive patients (N = 327) submitted to hepatic haemodynamic procedures (N = 355) in a tertiary care setting during 2011. VAS scores ranged between 0 and 100 mm and items were defined as excellent if <10 mm; good if 10–20 mm and inadequate if >20 mm. Clinical and laboratory data were also collected.ResultsSatisfaction was excellent in >95% of cases (mean 2 ± 5 mm, median 0 mm) and average tolerance was good (15 ± 18 mm; median 6 mm). A percentage of 59% of patients had excellent tolerance, 9% good and 32% had inadequate tolerance. Duration and complexity of the procedure and limited operator's experience were associated with inadequate tolerance on univariate analysis; duration of the procedure remained the only independent factor associated with inadequate tolerance on multivariate analysis. Procedures lasting <35 min had a >80% probability of being well tolerated.ConclusionsSatisfaction and tolerance to hepatic haemodynamic procedures are excellent and good respectively. Tolerance was decreased in long procedures; hence reducing as much as possible the duration of the procedures might further improve tolerance.
Fine‐mapping natural alleles: quantitative complementation to the rescue
Authors: Turner Thomas L. 
Published: March 2014

AbstractMapping the genes responsible for natural variation and divergence is a challenging task. Many studies have mapped genes to genomic regions or generated lists of candidates, but few studies have implicated specific genes with a high standard of evidence. I propose that combining recent advances in genomic engineering with a modified version of the quantitative complementation test will help turn candidate genes into causal genes. By creating loss‐of‐function mutations in natural strains, and using these mutations to quantitatively fail‐to‐complement natural alleles, fine mapping should be greatly facilitated. As an example, I propose that the CRISPR/Cas9 system could be combined with the FLP/FRT system to fine‐map genes in the numerous systems where inversions have frustrated these efforts.
Retraction statement for ‘Ethics and Integrity of the Publishing Process: Myths, Facts, and a Roadmap’ by Marshall Schminke and Maureen L. Ambrose
Authors: Tsui Anne S. , Lewin Arie Y. , Schminke Marshall , Ambrose Maureen 
Published: March 2014

The above article from Management and Organization Review, published online 7 SEP 2011, has been retracted by agreement between the authors, the journal's outgoing Editor-in-Chief Anne Tsui, the journal's incoming Editor-in-Chief Arie Y. Lewin, and John Wiley & Sons Asia Pty Ltd. The retraction has been agreed due to unattributed overlap with work previously published in Academy of Management Review, 34(4): 586–591: ‘Editor's comments: The better angels of our nature – Ethics and integrity in publishing process’ by Marshall Schminke. The editors and authors joindy wrote a letter, available below, to explain the process used to come to the retraction decision.The purpose of this letter is to explain the circumstances and reasons for the retraction of the paper ‘Ethics and integrity of the publishing process: Myths, facts, and a roadmap’ by Schminke and Ambrose in Management and Organization Review (MOR), Volume 7 issue 3, pages 397 to 406, November 2011.Retraction of a published paper due to self-plagiarism is an unpleasant if not painful experience for both journal editors and authors. Self-plagiarism means that authors have used materials in another paper (whether published or in working paper format) without attributing the source of the materials or ideas. In this instance, the materials being self-plagiarized are from an earlier editorial written by the lead author. Self-plagiarism is in violation of publication ethics, according to the Committee of Publication Ethics' guidelines on suspected plagiarism (http://publicationethics.org/files/u7140/plagiarism%20B_0.pdf).
Multicultural iteration:SwedishNationalDay as multiculturalism‐in‐practice
Authors: Schall Carly Elizabeth 
Published: March 2014

AbstractThis paper examines the creation of ‘national day’ inSweden in order to understand how such a holiday works to shape theSwedish nation's relationship with diversity. Analyzing parliamentary debates and press coverage, the author finds that official national day coverage tends to invest the nation with progressive and multicultural meanings, foregrounding immigrant voices. However, this multiculturalism is polysemic, vague and subject to contestation, both from far right ‘traditionalists’ seeking to ‘protect’Swedishness from outside influences and cosmopolitans who see the nation as outdated and dangerous. The creation of a new national holiday can be seen as a ‘democratic iteration’ wherein democracy is restated and reinvested with meanings, and new lines of cleavage are drawn, and also as a ‘multicultural iteration’ where multiculturalism is invested with new meaning. Finally, the author argues that multiculturalism benefits from polysemy in that the concept can then adapt to changing circumstances, and, thus, survive.