bluuebunny/crossref_metadata_2025_split huggingface dataset:
Livilla (daughter of Antonia Minor and Drusus)
Authors: Hopwood Bronwyn 
Published: June 2015

Abstract

Livilla (ca. 13
bce
–31
ce
), daughter of Drusus and Antonia Minor, was the sister of Germanicus (15
bce
–19
ce
) and Claudius (11
bce
–54
ce
). She was married to Gaius Caesar in 1
bce
, then Drusus the Younger in 4
ce
. With Drusus she produced a daughter and twin boys. In 31
ce
Livilla was accused of having helped her lover, the praetorian prefect Aelius Sejanus, poison Drusus in 23
ce
. After her death she suffered
damnatio memoriae
.
Medeon in Phokis
Authors: Livieratou Antonia 
Published: June 2015

Abstract
Medeon is a city with a long history of occupation lasting from the Early Helladic to the Hellenistic period. The citadel itself has not been excavated, but hundreds of tombs have been found in the area outside. A variety of burial customs is attested for all periods, while the offerings testify to prosperity and overseas contacts in the Late Bronze and the Early Iron Age.
Triumvirate, First
Authors: Russell Amy 
Published: June 2015

Abstract“First Triumvirate” is a modern and misleading name for the unofficial political alliance between Julius Caesar, Pompey, and Crassus which began in 60bce. Between them, the three men wielded unsurpassed influence over Roman politics over the following decade, though they also faced opposition. The breakdown of the alliance after Crassus’ death in 53bcewas the prelude to the eventual civil war between the two remaining partners, Caesar and Pompey.
Strong Single‐Band Blue Emission from Colloidal Ce3+/Tm3+‐Doped NaYF4 Nanocrystals for Light‐Emitting Applications
Authors: Adusumalli Venkata N. K. B. , Sarkar Shyam , Mahalingam Venkataramanan 
Published: June 2015

AbstractAn intense single‐band blue emission at λ=450 nm is observed from Tm3+ ions through Ce3+ sensitization, for the first time, in colloidal Ce3+/Tm3+‐doped NaYF4 nanocrystals. The intense Tm3+ emission through broad‐band excitation is advantageous for developing luminescent nanocomposites because they can be easily incorporated into polymers. The composites can easily be coated over UV light‐emitting diodes (LEDs) to develop phosphor‐based blue LEDs.
Tiled ChrI RHS collection: a pilot high‐throughput screening tool for identification of allelic variants
Authors: Singh Rohini , Sinha Himanshu 
Published: June 2015

AbstractReciprocal hemizygosity analysis is a genetic technique that allows phenotypic determination of the allelic effects of a gene in a genetically uniform background. Expanding this single gene technique to generate a genome‐wide collection is termed as reciprocal hemizygosity scanning (RHS). The RHS collection should circumvent the need for linkage mapping and provide the power to identify all possible allelic variants for a given phenotype. However, the published RHS collections based on the existing genome‐wide haploid deletion library reported a high rate of false positives. In this study, we report de novo construction of a RHS collection that is not based on the yeast deletion library. This collection has been constructed for the shortest yeast chromosome, ChrI. Using this ChrI RHS collection, we identified 13 allelic variants for the previously mapped loci and novel allelic variants for the growth differences in different environments. A few of these novel variants, which were fine mapped to a gene level, identified novel genetic variation for the previously studied environmental conditions. The availability of a genome‐wide RHS collection would thus help us uncover a comprehensive list of allelic variants and better our understanding of the molecular pathways modulating a quantitative trait. Copyright © 2014 John Wiley & Sons, Ltd.
Direct enzyme assay evidence confirms aldehyde reductase function of Ydr541cp and Ygl039wp from Saccharomyces cerevisiae
Authors: Moon Jaewoong , Liu Z. Lewis 
Published: June 2015

AbstractThe aldehyde reductase gene ARI1 is a recently characterized member of an intermediate subfamily within the short‐chain dehydrogenase/reductase (SDR) superfamily that clarified mechanisms of in situ detoxification of 2‐furaldehyde and 5‐hydroxymethyl‐2‐furaldehyde by Saccharomyces cerevisiae. Uncharacterized open reading frames (ORFs) are common among tolerant candidate genes identified for lignocellulose‐to‐advanced biofuels conversion. This study presents partially purified proteins of two ORFs, YDR541C and YGL039W, and direct enzyme assay evidence against aldehyde‐inhibitory compounds commonly encountered during lignocellulosic biomass fermentation processes. Each of the partially purified proteins encoded by these ORFs showed a molecular mass of approximately 38 kDa, similar to Ari1p, a protein encoded by aldehyde reductase gene. Both proteins demonstrated strong aldehyde reduction activities toward 14 aldehyde substrates, with high levels of reduction activity for Ydr541cp toward both aromatic and aliphatic aldehydes. While Ydr541cp was observed to have a significantly higher specific enzyme activity at 20 U/mg using co‐factor NADPH, Ygl039wp displayed a NADH preference at 25 U/mg in reduction of butylaldehyde. Amino acid sequence analysis identified a characteristic catalytic triad, Ser, Tyr and Lys; a conserved catalytic motif of Tyr–X–X–X–Lys; and a cofactor‐binding sequence motif, Gly–X–X–Gly–X–X–Ala, near the N‐terminus that are shared by Ydr541cp, Ygl039wp, Yol151wp/GRE2 and Ari1p. Findings of aldehyde reductase genes contribute to the yeast gene annotation and aids development of the next‐generation biocatalyst for advanced biofuels production. Copyright © 2015 John Wiley & Sons, Ltd.
Mark‐resight estimates of seasonal variation in harbor seal abundance and site fidelity
Authors: Cordes Line S. , Thompson Paul M. 
Published: June 2015

AbstractMonitoring trends in abundance of pinnipeds typically involves counting seals at terrestrial haul‐out sites during the breeding season. Counts of seals made at other times of the year are typically lower; however, it is often unknown whether this is because fewer animals are present or whether lower counts simply reflect a reduction in haul‐out probability. Here we illustrate how photo‐identification data from an individual‐based study of harbor seals (Phoca vitulina) can be used to estimate seasonal variation in abundance and site fidelity. Monthly data collected over a two‐year period were analyzed using a mark‐recapture mark‐resight model accounting for individuals transitioning between observable and unobservable states. Levels of site fidelity were high throughout the year and abundance estimates showed no seasonal pattern. This suggests that individual seals used haul‐out sites to the same extent throughout the year, and that peaks in counts during the breeding season are a result of seasonal changes in haul‐out probability. The results of this study have implications for understanding population sub‐structuring, gene flow and disease spread.
Prospective Validation of Central Line–Days Derived From an Electronic Medical Record System
Authors: Boyce John M. , Paci George , Feidner Carl , Hubbard Lori , Devin Laurie , Reilly Lenore , Gentile Anthony , Siner Jonathan M. 
Published: June 2015

Validation of the number of central line–days by hospitals is required by the National Healthcare Safety Network. A prospective study that compared a daily report of such days generated by an electronic medical record with observational audits by nurses revealed that the report was 100% sensitive and 99.9% specific.Infect. Control Hosp. Epidemiol. 2015;36(9):1098–1099
Contextual Distance and the International Strategic Alliance Performance: A Conceptual Framework and a Partial Meta-analytic Test
Authors: Li Jiatao (J.T.) , Tian Li , Wan Guoguang 
Published: June 2015

ABSTRACTWe propose an integrative model on how contextual distance influences the learning process and performance of international strategic alliances (ISAs). We argue that contextual distance increases knowledge diversity but decreases knowledge exchange between the alliance partners, which has implications for the alliance's knowledge creation and performance. A meta-analysis of 46 empirical studies published between 1990 and 2013 dealing with Sino-foreign collaborations in China revealed that contextual distance showed an inverted U-shaped relationship with alliance performance. Proxies for partners’ contextual experience, for example, the length of an alliance's operation in China, the foreign partners’ in-country experiences, and ISAs’ location in a more developed Chinese region, moderate the learning processes. Implications and directions for future research are discussed.
Adherence to cancer prevention recommendations and antioxidant and inflammatory status in premenopausal women
Authors: Morimoto Yukiko , Beckford Fanchon , Cooney Robert V. , Franke Adrian A. , Maskarinec Gertraud 
Published: June 2015

For cancer prevention, the World Cancer Research Fund and American Institute for Cancer Research (WCRF/AICR) emphasise recommendations to improve individual behaviour, including avoidance of tobacco products, maintaining a lean body mass, participating in physical activity, consuming a plant-based diet, and minimising the consumption of energy-dense foods, such as sodas, red and processed meats and alcohol. In the present study of 275 healthy premenopausal women, we explored the association of adherence scores with levels of three biomarkers of antioxidant and inflammation status: serum C-reactive protein (CRP), serum γ-tocopherol and urinary F2-isoprostane. The statistical analysis applied linear regression across categories of adherence to WCRF/AICR recommendations. Overall, seventy-two women were classified as low ( ≤ 4), 150 as moderate (5–6), and fifty-three as high adherers ( ≥ 7). The unadjusted means for CRP were 2·7, 2·0 and 1·7 mg/l for low, moderate and high adherers (Ptrend= 0·03); this association was strengthened after adjustment for confounders (Ptrend= 0·006). The respective values for serum γ-tocopherol were 1·97, 1·63 and 1·45 μg/ml (Ptrend= 0·02 before andPtrend= 0·03 after adjustment). Only for urinary F2-isoprostane, the lower values in high adherers (16·0, 14·5, and 13·3 ng/ml) did not reach statistical significance (Ptrend= 0·18). In an analysis by BMI, overweight and obese women had higher biomarker levels than normal weight women; the trend was significant for CRP (Ptrend< 0·001) and γ-tocopherol (Ptrend= 0·003) but not for F2-isoprostane (Ptrend= 0·14). These findings suggest that both adherence to the WCRF/AICR guidelines and normal BMI status are associated with lower levels of biomarkers that indicate oxidative stress and inflammation.
Inflammatory potential of diet and risk of colorectal cancer: a case–control study from Italy
Authors: Shivappa Nitin , Zucchetto Antonella , Montella Maurizio , Serraino Diego , Steck Susan E. , La Vecchia Carlo , Hébert James R. 
Published: June 2015

Diet and inflammation have been suggested to be important risk factors for colorectal cancer (CRC). In the present study, we examined the association between the dietary inflammatory index (DII) and the risk of CRC in a multi-centre case–control study conducted between 1992 and 1996 in Italy. The study included 1225 incident colon cancer cases, 728 incident rectal cancer cases and 4154 controls hospitalised for acute non-neoplastic diseases. The DII was computed based on dietary intake assessed using a validated seventy-eight-item FFQ that included assessment of alcohol intake. Logistic regression models were used to estimate the OR adjusted for age, sex, study centre, education, BMI, alcohol drinking, physical activity and family history of CRC. Energy intake was adjusted using the residual method. Subjects with higher DII scores (i.e. with a more pro-inflammatory diet) had a higher risk of CRC, with the DII being used both as a continuous variable (ORcontinuous1·13, 95 % CI 1·09, 1·18) and as a categorical variable (ORquintile 5v. 11·55, 95 % CI 1·29, 1·85;Pfor trend < 0·0001). Similar results were observed when the analyses were carried out separately for colon and rectal cancer cases. These results indicate that a pro-inflammatory diet is associated with an increased risk of CRC.
Modelling the impact of pulsed CAMP volcanism onpCO2and δ13C across the Triassic–Jurassic transition
Authors: BACHAN AVIV , PAYNE JONATHAN L. 
Published: June 2015

AbstractA sharp negative δ13C excursion coincides with the end-Triassic mass extinction. This is followed by a protracted interval of13C enrichment. These isotopic events occurred simultaneously with the emplacement of the Central Atlantic Magmatic Province (CAMP). Here we use a carbon cycle box model to explore the effects of episodic carbon release – constrained by recently developed high-resolution chronology – on atmosphericpCO2, ocean chemistry and the δ13C of the ocean–atmosphere carbon pool. Our results are consistent with previous modelling efforts in suggesting that the sharp negative δ13C excursion and acidification event associated with the extinction are best explained by the rapid release (<20 ka) of highly13C-depleted carbon (−70‰). However, our model also indicates that the likely short duration of the excursion requires organic carbon burial to have closely followed carbon injection. The age within the Hettangian of the large positive δ13C excursion which follows is currently uncertain. If early Hettangian in age, then our modelling indicates that the interval of13C enrichment was closely associated with the volcanic CO2pulses andpCO2peaks. If late Hettangian in age, then the13C enrichment must have lagged the carbon input substantially (by hundreds of thousands of years) and was associated with CO2drawdown and over-cooling. Our modelling highlights the need for improved age constraints on Hettangian stratigraphic sections in order to test between two distinct and contrasting possibilities: continuing carbon cycle instability due to recurrent perturbations from CAMP activity or a delayed recovery arising from internal biosphere dynamics.
Once Burned, Twice Shy: Money Market Fund Responses to a Systemic Liquidity Shock
Authors: Strahan Philip E. , Tanyeri Başak 
Published: June 2015

AbstractAfter Lehman’s collapse in 2008, investors ran from risky money market funds. In 27 funds, outflows overwhelmed cash inflows, thus forcing asset sales. These funds sold their safest and most liquid holdings. Funds were thus left with riskier and longer maturity assets. Over the subsequent quarter, however, the hard-hit funds reduced risk more than other funds. In contrast, money funds hit by idiosyncratic liquidity shocks before Lehman did not alter portfolio risk. The result suggests that moral hazard concerns with the Treasury Guarantee of investor claims did not increase risk taking. Funds that benefited most from the government bailout reduced risk.
Levels of infection and seasonal occurrence ofGyrodactylus alviga(Monogenea: Gyrodactylidae) on the whitingMerlangius merlangusoff the Turkish and Russian coasts of the Black Sea
Authors: Özer A. , Kornyychuk Y. , Öztürk T. , Yurakhno V. 
Published: June 2015

AbstractGyrodactylus alvigais a generalist species reported in many Black Sea fish species, but whiting is known to be its main host. It is the only monogenean parasite that has been reported so far on the skin, fins and gills of whitingMerlangius merlangusin the Black Sea. A total of 690 fish from Turkey and 423 fish from Russia were examined to detect parasites. Infection indices of prevalence, mean intensity and mean abundance values were calculated for length classes and sex of fish, as well as for the seasons. There is a gradual increase in infection indices in relation with increasing host length classes and there are higher infection indices on female fish. Furthermore, despite lower prevalence indices in spring and winter, higher parasite intensity values were determined in these seasons. It is concluded that larger fish provided more space and food forG. alviga, and female fish were more parasitized as they were more active in searching for food, which enables the parasite to switch between hosts. In addition, winter and spring were more appropriate for reproduction ofG. alviga.
A longitudinal twin study of borderline and antisocial personality disorder traits in early to middle adulthood
Authors: Reichborn-Kjennerud T. , Czajkowski N. , Ystrøm E. , Ørstavik R. , Aggen S. H. , Tambs K. , Torgersen S. , Neale M. C. , Røysamb E. , Krueger R. F. , Knudsen G. P. , Kendler K. S. 
Published: June 2015

Background.Antisocial personality disorder (ASPD) and borderline personality disorder (BPD) share genetic and environmental risk factors. Little is known about the temporal stability of these etiological factors in adulthood.Method.DSM-IV criteria for ASPD and BPD were assessed using structured interviews in 2282 Norwegian twins in early adulthood and again approximately 10 years later. Longitudinal biometric models were used to analyze the number of endorsed criteria.Results.The mean criterion count for ASPD and BPD decreased 40% and 28%, respectively, from early to middle adulthood. Rank-order stability was 0.58 for ASPD and 0.45 for BPD. The best-fitting longitudinal twin model included only genetic and individual-specific environmental factors. Genetic effects, both those shared by ASPD and BPD, and those specific to each disorder remained completely stable. The unique environmental effects, however, changed substantially, with a correlation across time of 0.19 for the shared effects, and 0.39 and 0.15, respectively, for those specific to ASPD and BPD. Genetic effects accounted for 71% and 72% of the stability over time for ASPD and BPD, respectively. The genetic and environmental correlations between ASPD and BPD were 0.73, and 0.43, respectively, at both time points.Conclusion.ASPD and BPD traits were moderately stable from early to middle adulthood, mostly due to genetic risk factors which did not change over the 10-year assessment period. Environmental risk factors were mostly transient, and appear to be the main source of phenotypic change. Genetic liability factors were, to a large extent, shared by ASPD and BPD.
Psychopathology arises from intertemporal bargaining as well as from emotional trauma
Authors: Ainslie George 
Published: June 2015

AbstractThe role of emotional trauma in psychopathology is limited. One additional mechanism is predictable from hyperbolic discounting: When a person uses willpower to control urges each success or failure takes on extra significance through recursive self-prediction, potentially motivating several constricting defense mechanisms. The need for eliciting emotion in psychotherapy is as the authors say it is, but their hypothesis about reconsolidation of memories adds no explanatory power.
Minding the findings: Let's not miss the message of memory reconsolidation research for psychotherapy
Authors: Ecker Bruce , Hulley Laurel , Ticic Robin 
Published: June 2015

AbstractThat memory reconsolidation is the process underlying decisive, lasting therapeutic change has long been our proposal, and the recognition of its critical role by Lane et al. is a welcome development. However, in our view their account has significant errors due to neglect of research findings and neglect of previous work on the clinical application of those findings.
A clinician's perspective on memory reconsolidation as the primary basis for psychotherapeutic change in posttraumatic stress disorder (PTSD)
Authors: Kimbrel Nathan A. , Meyer Eric C. , Beckham Jean C. 
Published: June 2015

AbstractLane et al.'s proposal that psychotherapeutic change comes about through memory reconsolidation is compelling; however, the model would be strengthened by the inclusion of predictions regarding additional factors that might influence treatment response, predictions for improving outcomes for non-responsive patients, and a discussion of how the proposed model might explain individual differences in vulnerability for mental health problems.
The nature of the semantic/episodic memory distinction: A missing piece of the “working through” process
Authors: Klein Stanley B. , Markowitsch Hans J. 
Published: June 2015

AbstractThe relations between the semantic and episodic-autobiographical memory systems are more complex than described in the target article. We argue that understanding the noetic/autonoetic distinction provides critical insights into the foundation of the delineation between the two memory systems. Clarity with respect to the criteria for classification of these two systems, and the evolving conceptualization of episodic memory, can further neuroscientifically informed therapeutic approaches.
Memory reconsolidation, repeating, and working through: Science and culture in psychotherapeutic research and practice
Authors: Levin Charles 
Published: June 2015

AbstractHypothesizing that an effective common feature in divergent forms of psychotherapy is a process of memory reconsolidation integrating new emotional experiences, Lane et al. usefully shift the focus away from established and/or specialized techniques to deeper questions about the underlying principles of psychotherapeutic change. More research attention to cultural factors influencing the definition and treatment of psychopathology is also needed.
Reconsolidation or re-association?
Authors: Llewellyn Sue 
Published: June 2015

AbstractThe target article argues memory reconsolidation demonstrates how therapeutic change occurs, grounding psychotherapy in brain science. However, consolidation has become an ambiguous term, a disadvantage applying also to its derivative – reconsolidation. The concept of re-association (involving active association between memories during rapid eye movement [REM] dreams followed by indexation and network junction instantiation during non-rapid eye movement [NREM] periods) brings greater specificity and explanatory power to the possible brain correlates of therapeutic change.
Top-down versus bottom-up perspectives on clinically significant memory reconsolidation
Authors: Marks-Tarlow Terry , Panksepp Jaak 
Published: June 2015

AbstractLane et al. are right: Troublesome memories can be therapeutically recontextualized. Reconsolidation of negative/traumatic memories within the context of positive/prosocial affects can facilitate diverse psychotherapies. Although neural mechanisms remain poorly understood, we discuss how nonlinear dynamics of various positive affects, heavily controlled by primal subcortical networks, may be critical for optimal benefits.
Reconsolidation: Turning consciousness into memory
Authors: Solms Mark 
Published: June 2015

AbstractThe purpose of learning is not to maintain records but to generate predictions. Successful predictions remain implicit; only prediction errors (“surprises”) attract consciousness. This is what Freud had in mind when he declared that “consciousness arises instead of a memory-trace.” The aim of reconsolidation, and of psychotherapy, is to improve predictions about how to meet our needs in the world.
Clinical applications of counterfactual thinking during memory reactivation
Authors: De Brigard Felipe , Hanna Eleanor 
Published: June 2015

AbstractThe Integrative Memory Model offers a strong foundation upon which to build successful strategies for clinical intervention. The next challenge is to figure out which cognitive strategies are more likely to bring about successful and beneficial modifications of reactivated memories during therapy. In this commentary we suggest that exercising emotional regulation during episodic counterfactual thinking is likely to be a successful therapeutic strategy to bring about beneficial memory modifications.
The relevance of maintaining and worsening processes in psychopathology
Authors: Mancini Francesco , Gangemi Amelia 
Published: June 2015

AbstractThe states called “psychopathology” are very diverse, but Lane et al.'s single-process explanation does little to account for this diversity. Moreover, some other crucial phenomena of psychopathology do not fit this theory: the role of negative evaluations of conscious emotions, and the role of emotions without physiological correlates. And it does not consider the processes maintaining disorders.