bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Coenzyme Q10 on early wound healing after recession coverage surgery with the modified coronally advanced tunnel technique and a connective tissue graft: A 6-month, triple-blinded, randomized, placebo-controlled pilot trial
Authors: Stähli Alexandra , De Ry Siro P. , Roccuzzo Andrea , Imber Jean-Claude , Sculean Anton 
Published: July 2024

AbstractObjectivesCoenzyme Q10 (CoQ10) or ubiquinone is one of a cell’s most important electron carriers during oxidative phosphorylation and many other cellular processes. As a strong anti-oxidant with further anti-inflammatory effects CoQ10 is of potential therapeutical value. The aim of this randomized controlled clinical trial was to investigate the effect of topical CoQ10 on early wound healing after recession coverage surgery using the modified coronally advanced tunnel (MCAT) and palatal connective tissue graft (CTG).Materials and methodsThirty patients with buccal gingival recessions were evaluated after being randomly allocated to: 1) MCAT and CTG with topical application of a coenzyme Q10 spray for 21 days or 2) MCAT and CTG with placebo spray. Wound healing was evaluated by the early wound healing index (EHI). Patient-reported pain was analyzed by a 100-mm visual analogue scale (VAS) at day 2, 7, 14 and 21 post-surgically. Mean recession coverage, gain of keratinized tissue and esthetic outcomes were assessed at 6 months.ResultsEHI and pain scores showed no significant differences. Time to recovery defined as VAS<10 mm was shorter in the test group. Mean root coverage after 6 months was 84.62 ± 26.57% and 72.19 ± 26.30% for test and placebo, p=0.052. Complete root coverage was obtained in 9 (60%) test and in 2 (13.3%) placebo patients. Increase in keratinized tissue width and esthetical outcomes were similar for both groups.ConclusionCoQ10 had no significant effect on early wound healing and on mean root coverage after 6 months.Clinical relevanceEarly wound healing: in young healthy patients with no inflammatory oral conditions topical CoQ10 does not improve early healing.
An initial user model design for adaptive interface development in learning management system based on cognitive load
Authors: Suryani Mira , Sensuse Dana Indra , Santoso Harry Budi , Aji Rizal Fathoni , Hadi Setiawan , Suryono Ryan Randy , Kautsarina  
Published: July 2024

AbstractThe cognitive aspect is crucial in developing interactive and adaptive systems, including learning management systems (LMS). By understanding human cognitive processes, developers can create adaptive systems that are sustainably used by targeted users. Cognitive traits need to be explored to become part of the user model, especially especially to develop an LMS with an adaptive interface based on cognitive load. However, there is limited research exploring the correlation between cognitive load and adaptive interfaces, as well as the visualization of information, within online learning settings, including those specifically within LMS platforms. Additionally, a lack of understanding of cognitive processes renders the use of LMS static and unable to adapt to learners’ abilities. Therefore, information regarding the specific characteristics or model of cognitive load that accurately represent LMS users as triggers for adaptive interfaces needs to be further examined. A total of four experts in the cognitive field were interviewed. The interview process was conducted in a semi-structured manner to obtain information about problems in the use of e-learning, the nature of cognitive, and the process of capturing cognitive load during learning using LMS. By using a soft system methodology, the results from the interviews are mapped into a cognitive load-based LMS user model design. The initial model design includes information on working memory capacity, task performance (time, true/false rate), learning behavior (learner log), physiological (in a lab scale), and self-reporting (Likert scale). This model design is a promising first step towards a more technical process in developing adaptive and interactive systems.
Ensuring People Living with HIV Inform the Future of HIV Treatment in Low- and Middle-Income Countries: A Scoping Review and Recommendations for a Community-Led Research Agenda
Authors: Resar Danielle F. , Sapire Rachel , Caldwell Benvy , Jenkins Sarah , Sikwese Kenly , Wambui Jacque , Nzano Brian , Amole Carolyn 
Published: July 2024

AbstractThe HIV treatment landscape in low- and middle-income countries (LMICs) is rapidly evolving, exemplified by the expansion of differentiated service delivery (DSD) during the coronavirus disease (COVID-19) pandemic. Long-acting products represent a new frontier that will require a significant redesign of health systems. It is critical to understand service delivery and product preferences of people living with HIV (PLHIV) and ensure evidence generation is guided by community priorities. We conducted a scoping review to identify gaps among preference studies and inform future research. Peer-reviewed articles published from January 2014-May 2022 reporting acceptability or preference data from PLHIV or caregivers for one or more service delivery or product attribute were eligible. Service delivery studies were restricted to LMIC populations while product studies had no geographical restrictions. Based on gaps identified, we consulted advocates to develop community-led research agenda recommendations. Of 6,493 studies identified, 225 studies on service delivery attributes and 47 studies on product preferences were eligible. The most frequently studied delivery models were integration (n = 59) and technology-based interventions (n = 55). Among product literature, only 15 studies included LMIC populations. Consultation with advocates highlighted the need for research on long-acting products, including among pediatric, pregnant, and breastfeeding PLHIV, PLHIV on second-line regimens, and key populations. Consultation also emphasized the need to understand preferences on clinic visit frequency, side effects, and choice. While the preference literature has expanded, gaps remain around long-acting regimens and their delivery. To fill these gaps, the research agenda must be guided by the priorities of communities of PLHIV.
Off-pump Versus On-pump Coronary Artery Bypass Grafting in Diabetic patients: A Meta-analysis of Observational Studies with a Propensity-Score Analysis
Authors: Ren Qiushi , Li Gang , Chu Tongxin , Liu Quan , Huang Yang , Liu KaiZheng , Pan Jinyu , Wu Zhongkai 
Published: July 2024

Abstract
Purpose
The debate between off-pump coronary artery bypass grafting (OPCAB) and on-pump coronary artery bypass grafting (ONCAB) in diabetic patients remains. This meta-analysis aimed to investigate outcomes after OPCAB versus ONCAB for patients with diabetes.

Methods
Literature research was conducted up to December 2023 using Ovid Medline, EMBASE, and the Cochrane Library. Eligible studies were observational studies with a propensity-score analysis of OPCAB versus ONCAB. The primary outcomes were early mortality and mid-term survival. The secondary outcomes were cerebrovascular accidents, reoperation for bleeding, incomplete revascularization, myocardial infarction, low cardiac output, and renal replacement therapy.

Results
Our research identified seven observational studies with a propensity-score analysis enrolling 13,085 patients. There was no significant difference between OPCAB and ONCAB for early mortality, mid-term survival, myocardial infarction, low cardiac output, and renal replacement therapy. OPCAB was associated with a lower risk of cerebrovascular accidents (OR 0.43; 95% CI, 0.24–0.76, P = 0.004) and reoperation for bleeding (OR 0.60; 95% CI, 0.41–0.88, P = 0.009). However, OPCAB was associated with a higher risk of incomplete revascularization (OR 2.07; 95% CI, 1.60–2.68, P < 0.00001).

Conclusion
Among patients with diabetes, no difference in early mortality and mid-term survival was observed. However, OPCAB was associated with a lower incidence of morbidity, including cerebrovascular accidents and reoperation for bleeding.
Disrupting Dehumanizing Norms of the Academy: A Model for Conducting Research in a Collective Space
Authors: Camargo Elsa , Ramos Delma , Bennett Cathryn B. , Talley Destiny Z. , Silva Ricardo G. 
Published: July 2024

Abstract
Academic research and knowledge production are frequently pervaded by elitism (Torres-Olave et al., 2019), epistemic exclusion (Dotson, 2014; Settles et al., 2020), and racialization (Ray, 2019; Thelin, 2019; Wilder, 2013). These discriminatory, exclusionary, and biased systems delegitimize the work of minoritized scholars, stifle innovation, and deter progress toward less violent processes to engage in knowledge production. Literature documenting innovative efforts to advance these commitments is scarce (Creamer, 2004), further underscoring the need and urgency for additional research examining how scholars incorporate and center equitable approaches in knowledge production in the Academy. As such, the central purpose of this qualitative autoethnographic study is to examine our experiences as minoritized scholars who center equity in the U.S. South; a secondary purpose of this work is to document the confluence of place, counterspace creation, and linkages between humanization and scholarly knowledge production. This research revealed our different yet shared negative socialization experiences in the Academy and, centrally, how our research collective diverges from traditionalist and power-imbalanced collaborative research. We foreground how we purposefully elect to humanize our fellow co-researchers, support each other’s learning and growth, and prioritize healing for ourselves as scholars with minoritized identities and transformation of the social inequities that permeate higher education. Based on our findings, we present a conceptual model of our research collective as a counterspace (Ong et al., 2018) to de facto scholarly socialization and dehumanization within the Academy.
Determination of Various Physical–Chemical Properties of bis(2-Methylbutyl) Itaconate and bis(3-Methylbutyl) Itaconate from Bio-Based Resources
Authors: Zapletal Martin , Dlugoš Tomáš , Plachý Marek , Sommer Tomáš , Trejbal Jiří 
Published: July 2024

AbstractAlternative sources for an industrial production of essential substances represent an exciting field of study for many researchers. Based on the previous research, itaconic acid and its esters were intensively studied as one of the sources. This paper relates to a determination of the basic physical–chemical properties of bis(2-methylbutyl) itaconate and bis(3-methylbutyl) itaconate that are produced from itaconic acid and 2-methylbutan-1-ol and 3-methylbutan-1-ol, respectively, from biomass. According to our best knowledge, physical–chemical properties of these substances, such as density, viscosity, and saturated vapor pressure, are not presented in the literature, and these are important for the future research of their production.
Weakly Compressible Two-Layer Shallow-Water Flows Along Channels
Authors: Shah Sarswati , Hernández-Dueñas Gerardo 
Published: July 2024

AbstractIn this paper, we formulate a model for weakly compressible two-layer shallow water flows with friction in general channels. The formulated model is non-conservative, and in contrast to the incompressible limit, our system is strictly hyperbolic. The generalized Rankine–Hugoniot conditions are provided for the present system with non-conservative products to define weak solutions. We write the Riemann invariants along each characteristic field for channels with constant width in an appendix. A robust well-balanced path-conservative semi-discrete central-upwind scheme is proposed and implemented to validate exact solutions to the Riemann problem. We also present numerical tests in general channels to show the merits of the scheme.
Disaster assessment from social media using multimodal deep learning
Authors: Shetty Nisha P. , Bijalwan Yash , Chaudhari Pranav , Shetty Jayashree , Muniyal Balachandra 
Published: July 2024

AbstractReal-time global event detection particularly catastrophic events has benefited significantly due to the ubiquitous adoption of social media platforms and advancements in image classification and natural language processing. Social media is a rich repository of multimedia content during disasters, encompassing reports on casualties, infrastructure damage, and information about missing individuals. While previous research has predominantly concentrated on textual or image analysis, the proposed study presents a multimodal middle fusion paradigm that includes Cross-modal attention and Self-attention to improve learning from both image and text modalities. Through rigorous experimentation, we validate the effectiveness of our proposed middle fusion paradigm in leveraging complementary information from both textual and visual sources.The proposed intermediate design outperforms current late and early fusion structures, achieving an accuracy of 91.53% and 91.07% in the informativeness and disaster type recognition categories, respectively. This study is among the few that examine all three tasks in the CrisisMMD dataset by combining textual and image analysis, demonstrating an approximate improvement of about 2% in prediction accuracy compared to similar studies on the same dataset.Additionally, ablation studies indicate that it outperforms the best-selected unimodal classifiers, with a 3-5% increase in prediction accuracies across various tasks. Thus, the method aims to bolster emergency response capabilities by offering more precise insights into evolving events.
Stability and change in maternal wellbeing and illbeing from pregnancy to three years postpartum
Authors: Mayerhofer Lilian , Nes Ragnhild Bang , Yu Baeksan , Ayorech Ziada , Lan Xiaoyu , Ystrom Eivind , Røysamb Espen 
Published: July 2024

Abstract
Purpose
Motherhood affects women’s mental health, encompassing aspects of both wellbeing and illbeing. This study investigated stability and change in wellbeing (i.e., relationship satisfaction and positive affect) and illbeing (i.e., depressive and anxiety symptoms) from pregnancy to three years postpartum. We further investigated the mutual and dynamic relations between these constructs over time and the role of genetic propensities in their time-invariant stability.

Data and methods
This four-wave longitudinal study included 83,124 women from the Norwegian Mother, Father, and Child Cohort Study (MoBa) linked to the Medical Birth Registry of Norway. Data were collected during pregnancy (30 weeks) and at 6, 18 and 36 months postpartum. Wellbeing and illbeing were based on the Relationship Satisfaction Scale, the Differential Emotions Scale and Hopkins Symptoms Checklist-8. Genetics were measured by the wellbeing spectrum polygenic index. Analyses were based on random intercept cross-lagged panel models using R.

Results
All four outcomes showed high stability and were mutually interconnected over time, with abundant cross-lagged predictions. The period of greatest instability was from pregnancy to 6 months postpartum, followed by increasing stability. Prenatal relationship satisfaction played a crucial role in maternal mental health postpartum. Women’s genetic propensity to wellbeing contributed to time-invariant stability of all four constructs.

Conclusion
Understanding the mutual relationship between different aspects of wellbeing and illbeing allows for identifying potential targets for health promotion interventions. Time-invariant stability was partially explained by genetics. Maternal wellbeing and illbeing develop in an interdependent way from pregnancy to 36 months postpartum.
Pragma-dialectics and the problem of agreement
Authors: Aikin Scott F. , Casey John 
Published: July 2024

AbstractPragma-Dialectics (PD) is an approach to argumentation that can be described as disagreement-centric. On PD, disagreement is the condition which defines argument, it is the practical problem to be solved by it, and disagreement’s management is the ultimate source of argument’s normativity. On PD, arguing in the context of agreement is taken to be “incorrect” and arguments where agreement already reigns are “pointless.” Even the PD account of fallacies is disagreement-centered: a fallacy is something that impedes resolution of a dispute. We argue here that the disagreement-focus of PD yields procedural errors of application in cases of arguments given explicitly for agreement-management, that there are explanations of fallacies better understood as agreement-focused (straw man and ad hominem in particular), and that there are unique meta-argumentative errors emergent in instances of agreement.
Can Siphon Hole Morphometrics Be Used for Population Assessments of Intertidal Soft-Shell Clams, Mya arenaria?
Authors: Clements Jeff C. , Harrison Sarah , Hunt Jillian , Brennan Isabelle , Hunt Heather L. , Sonier Rémi 
Published: July 2024

AbstractMeasuring infaunal population dynamics relies on destructive sampling that disturbs sediments and removes animals from their habitat. Establishing effective, non-invasive sampling methods for monitoring infaunal populations can reduce the impact of scientific sampling and facilitate efficient population assessments. Using intertidal soft-shell clams (Mya arenaria L.) in eastern Canada, we explored whether population density and size structure could be estimated from visible siphon holes. Across four sites with varying sediment characteristics and infaunal species assemblages, we predicted the presence of M. arenaria with 78–100% accuracy by visually assessing siphon holes. Smaller holes (< 7.5 mm) were more likely to be misidentified. Siphon hole count was a strong predictor of actual clam count and biomass at most sites, except the site with wet muddy sediment and high densities of other infaunal species. Siphon hole length was positively related to clam shell length and wet weight at all sites; however, relationships typically had low R2 values (< 0.35). Ultimately, visual assessments of intertidal siphon holes can be effective for estimating M. arenaria densities and size structure in some habitats. Testing the application of this method to other habitats and species is warranted.
Structural superlubricity at homogenous interface of penta-graphene
Authors: Zhang Xinqi , Fan Jiayi , Cui Zichun , Cao Tengfei , Shi Junqin , Zhou Feng , Liu Weimin , Fan Xiaoli 
Published: July 2024

AbstractTwo-dimensional (2D) van der Waals layered materials have been widely used as lubricant. Penta-graphene (PG), a 2D carbon allotrope exclusively composed of irregular carbon pentagons has recently been predicted to have superlubricating property. In the present study, by combining the molecular dynamics simulation and first-principles calculations, we investigated the frictional property of PG in both commensurate and incommensurate contacts. Our calculations show the ultra-low friction at the interface of relatively rotated bilayer PG with twist angles of more than 10° away from the commensurate configuration. Meanwhile, our calculations demonstrate the isotropy of the ultra-low friction at the interface of incommensurate contact, in contrast to the anisotropic of the commensurate contacting interface. Additionally, the evolution of friction force and the fluctuation of potential energy along sliding path correlate closely with the interface’s structure. The energetics and charge density explain the difference between the friction at the interfaces of the commensurate and incommensurate contacts. Not only that, we found the correlation between the intrinsic structural feature and interlayer binding energy. Importantly, our findings on the retainment of the ultra-low friction under work conditions indicates that the superlubricating state of PG has good practical adaptability.
Competing Influences of Earthward Convection and Azimuthal Drift Loss on the Pitch Angle Distribution of Energetic Electrons
Authors: Yuan H. C. , Li L. Y. , Yang L. , Cao J. B. 
Published: July 2024

AbstractUtilizing the multi‐point observations by Van Allen Probe A, GOES 13 and 15, we analyzed the competing influences of earthward convection and azimuthal drift loss on the pitch angle distributions of energetic electrons during the simultaneous increases in solar wind flow velocity and pressure. The increase in solar wind speed amplifies the dawn‐dusk convection electric field and causes the earthward transport of energetic electrons, and meanwhile the enhancement of solar wind dynamic pressure causes the inward displacement of dayside magnetopause and triggers the azimuthal drift loss of energetic electrons. The earthward convection of low‐energy electrons (<60 keV) is much faster than their azimuthal drift loss at most pitch angles, and the fast earthward convections make the butterfly‐like electron pitch angle distributions formed early become pancake‐like distributions. The 60–530 keV electrons maintain the butterfly‐like pitch angle distributions during the earthward convections, whereas the high‐energy electrons above 530 keV are not transported to the low‐L shells because of fast drift loss in the high‐L source region. The competition between the earthward convection and the azimuthal drift loss finally determines the pitch angle distributions of energetic electrons near the trapping boundary during the increases in solar wind flow speed and pressure.
Dexmedetomidine and argon in combination against ferroptosis through tackling TXNIP-mediated oxidative stress in DCD porcine livers
Authors: Chen Qian , Sun Jiashi , Liu Xiangfeng , Qin Zhigang , Li Jieyu , Ma Jianbo , Xue Zhengwei , Li Yirong , Yang Ziheng , Sun Qizhe , Wu Lingzhi , Chang Enqiang , Zhao Hailin , Zhang Yiwen , Gu Jianteng , Ma Daqing 
Published: July 2024

AbstractGraft availability from donation after circulatory death (DCD) is significantly limited by ischaemia reperfusion (IR) injury. Effective strategies to mitigate IR injury in DCD grafts are essential to improve graft quality and expand the donor pool. In this study, liver grafts from DCD pigs were preserved in the University of Wisconsin (UW) solution saturated with 0.1 nM dexmedetomidine (Dex) and various concentrations of noble gases Argon (Ar) and/or Xenon (Xe) at 4 °C for 24 or 72 h. The combined 50% Ar and Dex provided maximum protection to liver grafts by reducing morphological damage, apoptosis, necroptosis, ferroptosis, hepatocyte glycogen depletion, reticulin framework collapse, iron deposition, and oxidative stress. In vitro, human liver Hep G2 cells were preserved in the UW solution saturated with 0.1 nM Dex and 50% Ar in combination at 4 °C for 24 h, followed by recovery in medium at 37 °C for up to 48 h to mimic clinical IR injury. This treatment significantly increased the expression of anti-oxidative stress proteins by promoting the translocation of thioredoxin-interacting protein (TXNIP) to mitochondria, thereby inhibiting ferroptosis, increasing plasma membrane integrity, and maintaining cell viability.In summary, The combination of 0.1 nM Dex and 50% Ar may be a promising strategy to reduce ferroptosis and other form cell death, and preserve liver grafts.