bluuebunny/crossref_metadata_2025_split huggingface dataset:
Phosphopeptide-bridged NH2-TiO2-mediated carbon dots self-enhancing and electrochemiluminescence microsensors for label-free protein kinase A detection
Authors: Guo Jianping , Yue Lele , Ning Lingya , Han Ailing , Wang Junping 
Published: July 2024

Abstract

A novel electrochemiluminescence (ECL) method was developed for analyzing protein kinase A (PKA) ultra-sensitively based on amidated nano-titanium (NH2-TiO2) embellished carbon dots (Mg@N-CDs) fluorescent probe, which integrated the target recognition and ECL-signal enhancement. The Cys-labeled kemptides were employed to build a serine-rich synthetic substrate-heptapeptide (Cys-kemptide) on the Au-electrode surface. Then, the PKA-induced biosensor was triggered as a signal switch to introduce the large amounts of TiO2 decorated Mg@N-CDs nanohybrid (Ti@NMg-CDs) into AuE/Cys-phosphopeptides for signal output. In particular, the presence of PKA could induce the formation of Cys-phosphopeptides by the catalytic reaction between specific substrate (kemptide) and PKA, which could act as an initiator to link the Ti@NMg-CDs according to the bridge interactions Ti-O-P. By this way, multiple Cys-phosphopeptides were adsorbed onto a single Ti@NMg-CDs and the Ti@NMg-CDs not only provided the high specific selectivity but also large surface area, as well as unprecedented high ECL efficiency. Using this PKA-induced enhanced sensor, the limit-of-detection of the PKA was 4.89 × 10− 4 U/mL (S/N = 3). The proposed ECL biosensor was also universally applicable for the screening of PKA inhibitors and the determining of other kinases activity. Our sensing-system has excellent performance of specificity and the screening of kinase inhibitors, as well as it will inspire future effort on clinical diagnostics and new drugs discovery.
Preparation and Characterization of Fluorine and Magnesium co-doping LiNi0.8Fe0.1Al0.1O2 Cathode Materials for Lithium-Ion Batteries
Authors: Wu Huacheng , Huang Xinping , Li Jun 
Published: July 2024

Abstract

With the vigorous development of new energy vehicles, cobalt in the traditional lithium-ion(Li-ion) battery industry chain is obviously in short supply. To manage this challenge, a new cobalt free cathode material Li[Ni0.8Fe0.1Al0.1]1-xMgxO2-yFy (x=0.01, y=0.01, 0.02, 0.03) with different f-doping contents (labeled Mg-1, Mg-F-1, Mg-F-2, Mg-F-3) was prepared by sol-gel method. XRD results show that the co-doping of Mg2+ and F− reduces the mixing degree of cations and increases the lattice parameters. A small amount of Mg2+ and F− co-doping does not affect the layered structure of NFA materials. The results of SEM, EDS and elemental spectrum showed that Mg and F elements were evenly dispersed on the surface of the material and successfully doped into the crystal structure of the material. The co-doping of Mg2+ and F− did not damage the surface of NFA primary particles. XPS results further confirmed that Mg2+ and F− were introuduced successfully into NFA materials. Compared with the original NFA material, the co-doping of Mg2+ and F- significantly improved the electrochemical performance of the pirstine material. Electrochemical results show that co-doping has the best first discharge specific capacity, first coulomb efficiency and cycle life. The first discharge specific capacity and coulomb efficiency at 0.1C were 171.8 mAh g-1 and 88.1%, respectively. After 150 cycles at 0.1C, the capacity retention rate was 88.1%. This study emphasizes the broad prospects of this new material in the future cobalt free market.
Practical runtime verification of cross-organizational smart contracts
Authors: Kangogo Damaris Jepkurui , Péter Bertalan Zoltán , Klenik Attila , Kocsis Imre 
Published: July 2024

Abstract

Smart contracts in blockchains often implement critical functionality; consequently, their development time software fault detection, removal, and avoidance have been the target of intensive research. However, the applicability of runtime dependability mechanisms to smart contracts has not been explored systematically, mainly due to the transaction pricing models of public blockchains. In this paper, we propose a novel and practical runtime verification approach for Hyperledger Fabric, the leading cross-organizational blockchain platform, as an error detection facility for fault tolerance mechanisms; building on the proposition that, in contrast to the public setting, cross-organizational blockchains have ample computational headroom for their systematic use. We introduce a smart contract entity framework architecture with reusable domain models and encapsulated runtime verification. We describe Hypernate, our open-source implementation of the approach for Java smart contracts, which uses the Java Modelling Language for requirement specification and integrates the OpenJML verification tool. We demonstrate and evaluate the approach on a Fabric implementation of the TPC-C benchmark.
Analysis of the Matching Degree between Professional Needs and Professional Training Plans for Big Data Engineers
Authors: Rui Fang , Jingbai Tian 
Published: July 2024

Abstract

Aiming at the mismatch between the current college talent training model and the job market demand, this paper proposes a model based on big data analysis and natural language processing, taking big data engineers as an example. By collecting and analyzing the recruitment market data of enterprises, combining with NLP, entropy and weight normalization, this paper provides scientific basis for universities to formulate and adjust professional training programs. The model proposed in this paper can help colleges and universities to understand the market demand more accurately according to the current job market demand, and adjust and optimize the professional curriculum, so as to cultivate graduates who are more in line with the market demand. Through comparative analysis of recruitment information and professional training programs of colleges and universities, this study confirms this contradiction and proposes improvement strategies to improve the employment rate and career development success rate of graduates.
Traceability and dispersion of highly toxic soluble phases from historical mine tailings
Authors: Rio-Salas Rafael Del , Moreno-Rodríguez Verónica , Loredo-Portales René , Salgado-Souto Sergio Adrián , Valencia-Moreno Martín , Ochoa-Landín Lucas , Romo-Morales Diana 
Published: July 2024

Abstract

Dispersion of highly toxic elements associated with efflorescent crusts and mine tailings materials from historical mine sites threaten the environment and human health. Limited research has been done on traceability from historical mining sites in arid and semi-arid regions. Pb isotope systematics was applied to decipher the importance of identifying the mixing of lead sources involved in forming efflorescent salts and the repercussions on traceability. This research assessed mine waste (sulfide-rich and oxide-rich tailings material and efflorescent salts) and street dust from surrounding settlements at a historical mining site in northwestern Mexico, focusing on Pb isotope composition. The isotope data of tailings materials defined a trending line (R2 = 0.9); the sulfide-rich tailings materials and respective efflorescent salts yielded less radiogenic Pb composition, whereas the oxide-rich tailings and respective efflorescent salts yielded relatively more radiogenic compositions, similar to the geogenic component. The isotope composition of street dust suggests the dispersion of tailings materials into the surroundings. This investigation found that the variability of Pb isotope composition in tailings materials because of the geochemical heterogeneity, ranging from less radiogenic to more radiogenic, can add complexity during environmental assessments because the composition of oxidized materials and efflorescent salts can mask the geogenic component, potentially underestimating the influence on the environmental media.
Explanation of the Characteristics of Thermo diffusion and Buoyant Force in MHD Flow of Copper and Titanium Dioxide Nanoparticles Suspended in Water between infinite vertical Plates
Authors: Nazia S , Seshaiah B 
Published: July 2024

Abstract

This study explores the heat and mass transfer characteristics of an inconsistent, MHD condensed nanoliquid flow over a stretched sheet under a transverse magnetic field and thermal impacts. The theoretical framework examines two types of nanofluids, Ag-water-based and TiO2- water -based. By converting the governing differential equations into nonlinear ODE’s and subsequently employing a standard perturbation approach with appropriate boundary conditions, the solutions are obtained for various physical parameters. The graphical representation and comprehensive analysis of the consequences of these characteristics on dimensionless momentum, energy, and concentration outlines are presented. Comparisons with existing literature demonstrate favourable agreement. Tabulated numerical implications of material abundances, such as the local skin conflict, the local Nusselt numeral, and the local Sherwood numeral, are also furnished. The study reveals that increasing thermal radiation reduces velocity and temperature while enhanced chemical process efficiency decreases concentration levels. Moreover, an increased Soret parameter results in higher velocity and concentration measurements. Notably, TiO2 nanofluids exhibit significantly higher velocities compared to Ag nanofluids when based on water.
The effect of persistent acaricide residues on Varroa destructor population dynamics within honey bee colonies
Authors: Murcia-Morales María , Benito-Murcia María , Martín-Hernández Raquel , Fernández-Alba Amadeo , Higes Mariano 
Published: July 2024

Abstract

Continuous exposure of honey bee colonies to acaricides can affect Varroa destructor populations and their susceptibility to veterinary treatments. In this study, two groups of colonies were established using decontaminated wax or commercial wax (containing more pesticide residues). Both groups received two amitraz treatments and Varroa levels were monitored four times. Colonies containing contaminated wax exhibited consistently higher Varroa populations and the amitraz treatments had limited efficacy in reducing infestation, compared to colonies containing decontaminated wax. The findings suggest a connection between acaricide persistence and Varroa evolution, emphasizing the importance of indirect effects on honey bee behavior and colony dynamics.
Investigating Thermal Dynamic Behavior of Cryogenic Cooling for Low-Energy Impact Fracturing on ISO EN 1.0577 (S355J2) Mild Carbon Steel Grade Offshore Monopile Structures
Authors: Christensen Kenneth Bisgaard , Maheri Alireza , Siddiq M. Amir 
Published: July 2024

Abstract

This study delves into the significant area of low-energy impact fracturing within ISO EN 1.0577 (S355J2) mild carbon steel grade, exploring its cooling time depending on diverse temperature gradients across varying wall thicknesses. The cooling behavior is analyzed systematically to comprehend the material's structural dynamics under different thermal conditions. The findings, which are of utmost importance, offer insights into the nuanced interplay between temperature gradients and wall thickness, crucial for determining the cooling time needed to reach the desired temperature on the Ductile to Brittle Transition Temperature (DBTT) of the ISO EN 1.0577 (S355J2) mild carbon steel grade for the low-impact energy fracturing of the offshore structure depending on its wall thickness. The research not only delves into the mechanical aspects of low-energy impact fracturing but also unravels the thermal implications on cooling time depending on the desired temperature and the wall thickness of the mild ISO EN 1.0577 (S355J2) mild carbon steel structure, guiding engineering decisions for applications for low-energy impact fracturing added by cryogenic cooling of ISO EN 1.0577 (S355J2) mild carbon steel structure decommissioning.
3D path planning of unmanned ground vehicles based on improved DDQN
Authors: Tang Can , Peng Tao , Xie Xingxing , Peng Junhu 
Published: July 2024

Abstract

For safe and efficient path planning of unmanned ground vehicles in complex 3D environment, this paper proposes an improved deep reinforcement learning algorithm (Dual Experience Dynamic Target DDQN, DEDT DDQN) to solve the problems of sparse reward convergence and over-estimation that are difficulties for traditional DDQN algorithms in complex maps. The algorithm improves the performance of the DDQN algorithm in dealing with complex environments by dividing the input quality experience and dynamically fusing the a priori knowledge of DDQN and average DDQN for network parameter training. For unstructured 3D environments, this paper adopts a path planning strategy based on the digital elevation model (DEM) considering environmental characteristics and time cost. Simulation experiments of the DEDT DDQN algorithm in 3D maps modeled on realistic environments show that the DEDT DDQN algorithm reduces the number of inflection points and the average slope change by 40% and 16.7%, respectively, and improves the performance of optimization searching as well as the convergence speed by 5.34% and 60%, respectively. The proposed improved algorithm and adopted strategy can be applied in two different types of maps, which verifies the effectiveness and robustness of the algorithm and strategy.
Synthesis, characterization and impact of different carbon-based nanomaterials on gram (Cicer arietinum) plant growth and soil sustainability
Authors: Srivast Rajani , Awasthi Kalpana 
Published: July 2024

Abstract

The long-term use of chemical fertilizers negatively affects the environment and public health. Among many alternatives, applying carbon-based nanomaterials is a better option for maximizing plant growth acceleration while minimizing environmental damage. The objective of the present study is to evaluate carbon nanotubes (CNTs), functionalized carbon nanotubes (FCNTs), and graphene oxides (GO) on soil nutrient content and plant growth. We have synthesized and applied CNTs, FCNTs, and GO in the present study on gram plant growth and soil properties. Compared with the control (no nanomaterials), a 41% increase in crop height was noted in GO-treated crops, whereas this increase was 33% and 40% in FCNT and CNT-treated crops, respectively, after 90 days of seed sowing. Among treatments, the GO-treated plants showed a twofold increase in root length compared to the control whereas, this increase was 60% and 25% in FCNTs and CNTs-treated plants. GO-treated plants showed a maximum increase in plant biomass, soil organic matter, total nitrogen, microbial biomass, and enzymatic activity. Compared with the control, a 52% higher SDA was noted in GO-treated soil, whereas this, increase was 32% and 19% in FCNT and CNT-treated soils, respectively. Carbon-based nanomaterial is an organic substance that can regulate the soil microenvironment and has a certain activating effect on soil enzyme activity. The findings confirmed that adding carbon-based nanomaterials especially GO, to the soil may improve gram plant growth and soil sustainability.
Evaluation of Plant-Based Natural Extracts as Coagulants for Surface Water Treatment
Authors: Fida Zanib , Tanoli Muhammad Ashraf , Mahmood Qaisar , Alamgir Muhammad Sohail , Sajjad Dilawar 
Published: July 2024

Abstract
This study investigated the use of natural extracts as bio-coagulants for water treatment and purification. The utilization of natural materials represents important progress in sustainable environmental initiatives, and their application is directly associated with improved quality of life due to their low toxicity, cost-effectiveness, and naturally renewable properties. Therefore, three plant species were identified, and their effectiveness was evaluated in the laboratory on surface water samples: Moringa oleifera (MO), Cicer arietinum (CA), and Pinus roxburghii (PR). Water samples were collected from the River Kunhar, Garhi Habibullah (Mansehra) for laboratory analysis. A combined treatment (coagulation and filtration) was found to be more efficient compared to direct filtration or coagulation alone. The highest turbidity removal of 99.17 percent, solids reduction of 93.21 percent, hardness reduction of 67.35 percent, and total coliform removal of 86.13 percent were achieved for the filtered water samples treated with MO. CA provided the maximum chloride reduction of 54.85 percent compared to the other two. These extracts slightly affected the acidity, alkalinity, pH, and conductivity of water samples. However, a slight increase in biological and chemical oxygen demand was found in treated water. Among the three natural coagulants, MO caused a significant increase in organic matter. This problem can be avoided by using the purified form of active coagulating agents rather than crude extract. This research shows the effectiveness of MO for surface water treatment and also illustrates the great potential of CA and PR as promising bio-coagulants for the treatment of polluted surface water samples.
Hydrochemical Delineation of Spring Recharge in an Urbanized Karst Basin, Central Kentucky
Authors: Fryar Alan E. , Currens Benjamin J. , Villa Cristopher S. Alvarez 
Published: July 2024

ABSTRACT
Because of well-integrated surface and subsurface drainage in karst terrains, springs can exhibit relatively rapid hydraulic, chemical, and thermal responses to storms. In urbanized karst basins, impervious cover, stream channelization, and utility infrastructure can alter infiltration, provide alternate pathways for subsurface flow, and affect ambient water quality. We combined continuous logging of electrical conductivity (EC) and water temperature with analyses of stable isotopes (deuterium and oxygen-18) to differentiate focused and diffuse recharge in a karst basin in Lexington, Kentucky, during 2018. Logging occurred at the McConnell Springs Blue Hole and a sinkhole that drains to it; isotopes, specific conductance, and temperature were manually monitored at those sites and along two losing stream reaches. Water temperature at McConnell Springs and stable isotope abundances showed seasonal variability. The Blue Hole responded within hours to stormwater infiltration at the sinkhole (∼2.1 km upgradient), with recharge events marked by colder stormwater in winter and warmer stormwater in spring to early autumn. Stable isotopes indicated that sinkhole infiltration was minimally affected by evaporation during periods of ponding (up to 9 days). Spring discharge appeared to represent a mixture of focused and diffuse, partly evaporated recharge, consistent with a simple hydrologic model of rainfall, runoff, and infiltration in the basin. EC spikes at the spring during January–March were consistent with pulses of road salt or brine in runoff or snowmelt. Despite limited monitoring data, results suggest that restoration of the sinkhole and its inlet stream were effective in stormwater management during an un usually wet year.
Nastawienie dorosłych do rozwijania duchowości dzieci w wieku wczesnoszkolnym w kontekście zdrowia psychicznego młodego pokolenia
Authors: Leszcz-Krysiak Agnieszka , Wardal Andrea , Fiedorczuk Natalia 
Published: July 2024

Artykuł ma charakter badawczy, a jego celem jest skoncentrowanie uwagi na zdrowiu psychicznym dzieci i młodzieży w kontekście ich rozwoju duchowego oraz próba określenia miejsca edukacji w tej przestrzeni. Jako metodę badawczą przyjęto sondaż diagnostyczny, w ramach którego wykorzystano ankietę internetową. Grupa respondentów liczyła łącznie 209 osób, spośród których rodzice stanowili 54 osoby, nauczyciele – 55, a instruktorzy harcerscy 100 osób. Kobiety stanowiły 83,7% ankietowanych. Do celów badawczych wyodrębniono kilka kategorii, które odnoszą się do wiary i religijności; transcendencji i zjawisk nadprzyrodzonych; uczuć, życia wewnętrznego; stanu umysłu, świadomości; zdolności i umiejętności; sposobu i stylu życia. Wyniki badań wykazały niewystarczające przygotowanie badanych osób do kształtowania rozwoju duchowego dzieci i młodzieży, ponieważ tylko 14,8% respondentów uznało, że w ramach zdobytej edukacji uzyskało kompleksową wiedzę na temat rozwoju duchowego.
Field Study on the Assessment of Antimalarial Drug Quality Using Minilab Kitin India
Authors: Noor Saba , Sharma Supriya , Arora Taruna 
Published: July 2024

Background:
A lack of proper anti-malarial medication use can lead to drug resistance, failed therapy, and even death. It is unclear how widespread the use of
fake anti-malarial medications is in India. Better malaria treatment and the execution of regulatory initiatives to improve anti-malarial drug quality
necessitate regional research into the quality of available anti-malarial pharmaceuticals. This study aimed to look into the quality of anti-malarial
drugs in regions of India where malaria is common. Conclusions about the prevalence of substandard anti-malarial medications in Indian
communities can be drawn from the findings.

Methods:
Samples of anti-malarial pills were bought from stores in five different Indian areas. One hundred and fifty anti-malarial drug samples were
gathered. Using a GPHF minilab lab kit, the quality of the following samples was determined: chloroquine (n=50), artemether lumefantrine (n=50),
artesunate sulphadoxine-pyrimethamine (n=14), and primaquine (n=31).

Results:
This research confirmed that 98% of the tablets disintegrated properly in a minilab disintegration test. As a result, when compared to both the full
set of standards and 80% of the samples, 99% of the samples passed the preliminary qualitative TLC test. Only 4% of samples (those with
insufficient amounts of the active medicinal component) failed the quantitative HPLC test.

Conclusion:
Anti-malarial medicine counterfeiting has been found to be quite uncommon in India compared to other countries. However, further research is
needed, such as post-marketing surveillance, to ensure that effective anti-malarials are distributed to the public.