bluuebunny/crossref_metadata_2025_split huggingface dataset:
ANOMALOUS ORIGIN OF THE CIRCUMFLEX CORONARY ARTERY FROM THE RIGHT CORONARY SINUS OF VALSALVA: DIAGNOSIS AND COURSE
Authors: Kurako Mariya M. , Abramyan, Mikhail A. , Bedin Aleksey V. 
Published: July 2024

HighlightsAnomalous origin of the circumflex coronary artery from the right sinus of Valsalva is the most common anomaly of the coronary arteries.In children, this anomaly still remains an unrecognized, unnoticed and misinterpreted pathology. AbstractAim. The aim of the study was to evaluate the effectiveness of transthoracic echocardiography (TTE) in case of anomalous origin of the circumflex coronary artery from the right coronary right sinus of Valsalva in children.Methods. During a routine examination at the Department of Emergency Cardiac Surgery and Interventional Cardiology of the Morozov Children's City Clinical Hospital of Moscow from January 2022 to August 2023, anomalous origin of the circumflex coronary artery from the right coronary sinus was detected in 10 children. The criterion for the diagnosis of anomalous origin of the circumflex coronary artery from the right sinus of Valsalva were RAC and bleb signs on TTE.Results. According to TTE, all 10 children have crossed aorta signs in apical five- and four-chamber projection in the form of a tubular image above the plane of the mitral valve. Only 2 patients undergoing TTE presented with the bleb sign. 7 children underwent coronary computed tomography angiography, and 5 of these patients presented with an anomalous origin of the circumflex coronary artery from the right sinus of Valsalva and 2 patients with an anomalous origin of the circumflex coronary artery from the proximal segment of the RCA. According to CT data, all 7 patients had a retroaortic course of the circumflex artery without signs of narrowing or compression, the angle of divergence in all cases was less than 45°. 3 patients underwent coronarography before the RFA, the data of the study confirmed the diagnosis as well. All 10 patients (100%) had negative bicycle stress echocardiogram results.TTE in experienced hands can provide valuable information about anomalies of the coronary arteries in children and thereby save time and reduce the cost of expensive diagnostic methods. Children with congenital heart defects and concomitant CA anomalies are at risk for coronary complications, since many of these patients are potential candidates for surgical intervention on the aortic valve/root throughout life. Therefore, timely diagnosis of CA anomaly before surgery is crucial for understanding the spatial interaction between the retroaortic coarse of the CA and the valve/root of the aorta.Conclusions. TTE is a cost-effective and non-invasive tool for screening patients that has a vital role in the diagnosis of anomalous origin of coronary arteries in children. Patients with an enlarged aortic root and a divergence of the circumflex artery from the right coronary sinus at an acute angle should be under the supervision of a cardiologist for timely prevention of cardiovascular complications.
THE EFFECTIVENESS OF XENO-PERICARDIAL PATCH IN REVASCULARIZATION OF AN ISCHEMIC LIMB USING THE DEEP FEMORAL ARTERY
Authors: Sukovatykh Boris S. , Sukovatykh Mikhail B. , Gordov Maksim Yu. , Grigoryan Arsen Yu. 
Published: July 2024

HighlightsThe choice of method for revascularization of the ischemic lower limb remains an important issue in cardiovascular surgery. Of the available methods, the most effective, in our opinion, is revascularization of the limb using the deep femoral artery. In this case, it is necessary to carefully select the material for the expanding patch, which prevents the development of restenosis. AbstractAim. To compare the effectiveness of autovenous and xeno-pericardial patches in revascularization of an ischemic limb using a deep femoral artery.Methods. An analysis of the comprehensive examination and treatment of 30 patients with critical ischemia, who were divided into 2 statistically homogeneous groups of 15 people each, was carried out. In the first group, an autovenous patch was used to repair the deep femoral artery, and in the second group, a xeno-pericardial patch was used. The short-term results of treatment were assessed by the number of postoperative complications, ankle brachial index and the clinical picture of the disease 1 month after surgery, whereas the long-term results were assessed by the deep femoral artery patency and the quality of life of patients.Results. 6 complications of the same type were registered in 4 (13.3%) patients, two in each group. After 1 month, the ankle brachial index in the first group was 0.58±0.12, and in the second 0.61±0.13. All patients in both groups had relief of pain at rest, an increase in pain-free walking distance, and trophic disorders healed. After 5 years, the deep femoral artery in the first group remained passable in 11 (73,3%) patients, and in the second – in 15 (100%) patients. The physical component of the health of patients in the first group scored 41.7±3.4, in the second group – 48.6±3.4, and the psychological component of health scored 52.1±3.9 and 56.9±3.6, respectively.Conclusion. Xeno-pericardial patches proved to be more effective in revascularization of an ischemic limb using a deep femoral artery compared with autovenous patches in the long-term postoperative period.
COMPARATIVE ANALYSIS OF MITRAL VALVE REPAIR AND REPLACEMENT USING BIOLOGICAL PROSTHESIS IN ELDERLY PATIENTS (PSM method)
Authors: Kuzmina Olga K. , Stasev Alexander N. , Dvadtsatov Ivan V. , Blinova Anna V. , Osintsev Eugenii S. , Evtushenko Aleksey V. , Barbarash Olga L. , Barbarash Leonid S. 
Published: July 2024

HighlightsAs evidenced in literature, mitral valve (MV) repair for mitral regurgitation has many advantages, however, elderly patients have an extremely low risk of valve tissue degeneration, thus making the use of this type of surgery in this patient population controversial. Aim. To analyze the role of bioprostheses in the older age group of patients undergoing mitral valve replacement and compare the results to mitral valve repair outcomes.Methods. The study included elderly patients (over 65 years old) with mitral regurgitation who underwent mitral valve repair and annuloplasty using the biological annuloplasty ring NeoRing (Neokor CJSC, Kemerovo) or the annuloplasty ring RIGID (NPP MedInj CJSC, Penza) (n = 19) at the Research Institute for Complex Issues of Cardiovascular Diseases (Kemerovo, Russian Federation). To select pairs from a larger group of UniLine recipients for a sample of patients with annuloplasty rings, pseudorandomization (propensity score matching) was performed using the STATA 13.0 software package (StataCorp, USA) by identifying nearest neighbors.Results. Patients of both groups did not experience thromboembolic and hemorrhagic complications during in-hospital period or 1-year follow-up period. At the same time, in the MV repair group, there was one case of new-onset atrial fibrillation, as well as two in-hospital cardiac deaths (due to myocardial infarction, and during surgery for recurrence of mitral regurgitation grade ≥ 2). One nonvalvular death (covid pneumonia) was recorded in the groups of UniLine recipients during the 1-year follow-up period.Conclusions. Taking into account that in the vast majority of Russian clinics MV replacements prevail over MV repairs, elderly patients undergoing mostly MV replacement and receiving bioprostheses can be justified because the outcome is comparable to results of MV repair, primarily due to the lack of need for long-term anticoagulant therapy and comparable stable hemodynamic results in both groups.
MEDICAL DEVICE MANAGEMENT BASED ON A PROCESS APPROACH
Authors: Artamonova Galina V. , Avramenko Olesya E. , Popsuiko Artem N. , Milinevskiy Nikolay I. 
Published: July 2024

HighlightsScientific novelty and practical significance of the presented work is seen in the relationship between the development of medical equipment management system and quality management in health care institutions and medical science. The application of the principles of international ISO 9001:2015 to the system of medical equipment management, which has its own special features in this industry makes the author’s approach unique. The role of the process approach in ensuring the sustainable functioning of medical equipment is shown in the study. The performance of the medical equipment management system based on the principles of international standard ISO 9001:2015 has been analyzed. The positive dynamics in terms of achieving the target performance indicators of this process in 2013–2021 is revealed.Aim. To analyze the experience of applying the process approach in the management of medical equipment based on the principles of the international standard ISO 9001:2015.Methods. The basis of the study was “Research Institute for Complex Issues of Cardiovascular Diseases” (NII KPSSZ). The object of the study is the quality management system of the Research Institute for Complex Issues of Cardiovascular Diseases. The subject of the study is the process of equipment and measuring instruments management. The main methods of this study were: system analysis, unity of historical and logical. The period of the study was 2013–2021.Results. The process approach in medical device management is considered within the framework of the quality management system of NII KPSSZ. During the study period there was an increase in equipment units by 2.58 times (from 976 to 2520 units, respectively, 2013–2021), which led to an increase in scheduled maintenance (SM) by 4.25 times (due to the introduction of pre-checking maintenance). The relative number of repairs to the total amount of equipment in different years amounted to 33.4–54.3% or on average 40.3%, the increase in current repairs of medical equipment relative to 2013 in 2021 amounted to 2.68 times. There is a positive dynamic in terms of decrease in the number of comments and increase in the number of proposals to improve the process during 2013–2021.Conclusion. The analysis of performance indicators in the period under the study indicates the determining role of the quality management system in ensuring the sustainability and stability of the medical equipment management system. The implementation of research tasks allowed the authors to form a holistic vision of the role of the process approach in solving the problem of finding effective organizational solutions that ensure the quality and safety of medical care. The presented experience can be replicated for any medical organization.
PROGNOSTIC SIGNIFICANCE OF ELECTROCARDIOGRAPHIC PARAMETERS ASSOCIATED WITH METABOLIC CHANGES IN THE MYOCARDIUM (LITERATURE REVIEW)
Authors: Kuzminykh Natalia A. , Ragino Yulia I. 
Published: July 2024

Highlights The main ECG parameters associated with cardiovascular mortality in metabolic cardiomyopathy are P-wave changes, QT prolongation, ECG signs of left ventricular hypertrophy, depression and ST segment elevation, T-wave changes. These simple ECG markers are valuable signs of an unfavorable prognosis in patients with myocardial metabolic disorders. AbstractCardiovascular diseases (CVD) are the leading cause of death globally, one of the initial manifestations of these diseases are metabolic changes in the myocardium. Risk stratification in a young population makes would make it possible to timely identify such conditions and prevent their development, as well as their further progression. Electrocardiography is an effective, reliable, accessible and inexpensive method used in clinical practice and research. The aim of this article was to review electrocardiographic (ECG) features associated with manifestations of myocardial metabolic disorders, the mechanisms underlying these associations, and to briefly describe the main research findings in this area and consider the implications for clinical practice. The material and methods were literature sources analyzing metabolic changes in the myocardium and their electrophysiological manifestations, the following databases were used to search for relevant articles: elibrary.ru, pubmed.ncbi.nlm.nih.gov, researchgate.net. The results of the analysis showed that the main changes in ECG parameters associated with cardiovascular mortality in metabolic cardiomyopathy are P-wave changes, QT prolongation, ECG signs of left ventricular hypertrophy, depression and ST segment elevation, T-wave changes. Thus, simple ECGs-markers remain valuable indicators of an adverse prognosis for patients with metabolic disorders of the myocardium.
Retelling Yassawi’s Hikmets: The impact on EFL students’ English-speaking performance and vocabulary size
Authors: Suleimenova Zhazira , Kenesbayeva Shynar , Tussupova Gulden , Saganayeva Gulnur , Kaliyeva Assel 
Published: July 2024

This experimental study evaluates the effects of retelling Yassawi’s hikmets on the speaking performance and vocabulary size of English as a Foreign Language (EFL) learner. Sixty EFL students recruited from a university in Kazakhstan were asked to narrate monologues based on previously read hikmets of their choice during out-of-class meetings once a week over 10 weeks. The results reveal that this intervention significantly improved participants’ speech fluency, lexical complexity and vocabulary size as opposed to their counterparts who did not engage in the retelling experience. However, the analysis of covariance revealed that only fluency and lexical complexity showed significant differences after controlling for the pre-test scores of these variables and vocabulary size. It was also found that pre-test vocabulary size and fluency had a moderating influence on post-test fluency. In a nutshell, retelling hikmets brought about gains in learners’ vocabulary and speaking performance especially in terms of fluency. This evidence underscores the effectiveness of oral text reproduction exercises in improving the speaking abilities and vocabulary of EFL learners even when the recited text is out-of-date and not really engaging. The findings advance our understanding of effective language teaching methods and offer practical guidance for EFL teachers, curriculum developers and researchers.
Examining the reliability and validity of measuring scales related to informatization and instructional leadership using the PLS-SEM approach
Authors: Li Wei , Lay Yoon Fah 
Published: July 2024

This study focuses on six variables that impact teachers' use of technology in their instructional leadership: usage expectancy (UE), social influence (SI), enabling circumstances (FC), behavioural intention (BI), computer self-efficacy (CSE) and blended teaching competency. This study aimed to examine the reliability and validity of modified scales incorporating UE scales including the PE scale, EE scale, SI scale, FC scale, CSE scale, BTC scale, BI scale and TIIL scale. A total of 60 in-service university teachers participated in this research. The PLS-SEM approach was employed to examine the reliability and validity of all scales. Composite reliability (CR) and Cronbach’s alpha determine internal consistency and reliability. Convergent validity was assessed by the outer loading and the average variance extracted (AVE). Assessment of discriminant validity was conducted by the Fornell-Larcker criterion, cross-loadings and Heterotrait-Monotrait Ratio (HTMT). After deleting nine items that were lower than .40, Cronbach’s alpha and CR values were all higher than .70. All scales’ item values fulfilled the criteria of AVE (>.50), Fornell-Larcker criterion, cross-loading and HTMT(<.90). Assessment results indicate that all modified scales have established validity and reliability for in-depth research. This research contributed to the PLS-SEM research technique, examined TIIL's influencing elements in the Chinese environment, enhanced the theoretical model of TIIL and provided useful assistance for the field's advancement.
Retrospective Observational Analysis of Tocilizumab Outcomes in COVID-19 Patients at a Tertiary Care Hospital
Authors: Aringale Vrushali , Daswani Bharti , Fernandes Madeline 
Published: July 2024

Background: Tocilizumab (TCZ), a monoclonal antibody against interleukin-6 (IL-6), was recommended for treatment of Covid-19 patients with a risk of cytokine storm but showed variable effect on outcome. The aim was to assess the association of outcome following tocilizumab administration with various physiological, pathological and pharmacological factor in Covid- 19 patients
Methods: Retrospective observational study from June 2020 to July 2020. All indoor Covid positive patients who received tocilizumab were included and relevant information was captured in the case record form. Data was analyzed to the study association of various physiological factors, comorbidities, severity of disease, laboratory parameters and co-administered drugs with the outcome following tocilizumab administration.
Results: Total 25 patients received tocilizumab during study period. Older age group (p=0.001), high NEWS score, hypertension (OR: 3.62; p=0.05) and hydroxychloroquine(HCQ) administration (OP=6.66; p=0.009) showed significant association with a worst outcome. Hypertension and hydroxychloroquine usage was analyzed after adjustment with NEWS score using MH adjusted analysis, which revealed a trend of worst outcome in HCQ recipients but the association was not significant with hypertension. High pre-treatment IL-6 (death 570.11+498.76; discharge110.31+ 49.68; p: 0.0011); high post-treatment ferritin level (death 1756.5+ 1622.03; discharge 711.71+ 421.23; p: 0.019) as well as post-tocilizumab rise in ferritin level was associated with worst outcome (p= 0.029).
Conclusion: Participants having higher cytokine level/or high NEWS score were unlikely to benefit from tocilizumab. Increased in ferritin level even after tocilizumab appeared to be an indicator of failure of treatment.
Knowledge and Awareness of Disposal of Unused and Expired Medicines among Healthcare Professionals in Tertiary Care Hospital: A Brief Report
Authors: Nagothkar Sanjivani Krishna , Waghmare C. S. , Shirure Prashant Ashok , Bansode Amit , Mukadam Fehmi M. , Ali Dilara Parvin , Chavarkar Pranali Naresh 
Published: July 2024

Background: The incidence and prevalence of diseases are increasing, which has resulted in a huge increase in the use of medications. However, when they were no longer required/remained unused due to various reasons, they had to be disposed of. Since the drugs are chemicals, their expiration date indicates the amount of time that the product is anticipated to remain stable. Consumption of expired drug can result in efficacy loss, safety concerns, potency loss.
Methods: This cross-sectional questionnaire-based study evaluated knowledge, attitude and practice of drug disposal among healthcare professionals especially junior residents in tertiary health care centre. The data were collected through a google form and expressed in percentage.
Results: Out of 200, a total of 133 participants have completed the survey, which includes 42% males and 58% females. A total of (97.7%) participants were aware that improper disposal of unused and expired medicines affects the environment and health. However, (97%) of the respondents answered that the drug take back programmes should be included in the communities.
Conclusion: Majority of the study participants reported that they have unused medications at home, and throwing them in the household garbage is the most common method of getting rid of them. It is important to educate people on the correct way to dispose of unused and expired medications, and a drug take-back program in communities could be the solution to this issue.
Third Nerve Palsy: Rare Adverse Event following Covid-19 Vaccination
Authors: Deshmukh Indira B , Burute Sheyas R , Pore Shraddha , Singh Atmik 
Published: July 2024

Drugs Controller General of India (DCGI) in April 2022 approved the emergency use authorisation of Corbevax and Covaxin COVID 19 vaccines in children. Corbevax is a protein subunit COVID 19 vaccine developed by Texas Children's Hospital. Third nerve palsy is rarely reported following protein sub- unit COVID vaccines. We report a case of a 13-year-old male who presented to a tertiary care hospital with complaints of giddiness, headache, diplopia and drooping of left eye within one hour of receiving Corbevax vaccine in school. He was subsequently diagnosed with third nerve palsy and treated with corticosteroids and lubricant eye drops. He recovered fully and was discharged after four days. Causality assessment as per World Health Organization (WHO) guidelines for the causality assessment of Adverse Events Following Immunization (AEFI) was consistent. Protein sub unit vaccines can rarely cause third nerve palsy.
Team trust as a predictor of collective efficacy in female rugby players
Authors: Brown Kate E 
Published: July 2024

According to Bandura’s (1997) social cognitive theory, “the higher the sense of collective efficacy, the better the team performance”. Bandura also states that collective efficacy is greater than the sum of its individual self-efficacies due to it being influenced by other cognitive factors, including trust (1986, 1997, J Cog Psychother, 13, 158-166). Therefore, the purpose of this study was to investigate the influence of team trust on the construct of collective efficacy within a sport context. It is proposed that team trust is an important cognitive factor that may precede the relationship between collective efficacy and group performance. With institute ethical approval (BREO:33249-A-Nov/2023-47988-1), 21 female college rugby players voluntarily completed the four factor Team Trust Scale (Costa & Anderson, 2011. Eur J Work Org Psych, 20, 119-154) and the five factor Collective Efficacy Questionnaire for Sport (Short, Sullivan. & Feltz, 2005, Meas Phys Ed Ex Sci, 9, 181-202) to measure the correlation between levels of team trust and collective efficacy and determine if team trust is indeed a valid predictor of collective efficacy. Linear regression analyses were conducted and correlation coefficients calculated using Pearson’s correlation. It was predicted that a positive correlation would be shown between the two constructs and that team trust is a significant predictor of collective efficacy. Assuming a positive hypothesis, the study recommends that rugby teams and interdependent sport teams, generally, should develop a high-quality environment of trust both on and off the pitch, given its relationship with collective efficacy and subsequent impact on performance. Relatively little research has been carried out into the effect of intrateam trust within sport and, therefore, this study serves to widen the exploration of this construct and its impact on other social constructs such as collective efficacy and their impact on team performance.