bluuebunny/crossref_metadata_2025_split huggingface dataset:
Optimizing plant growth, nutrient uptake, and yield of onion through the application of phosphorus solubilizing bacteria and endophytic fungi
Authors: Arunachalam Thangasamy , Gade Komal , Mahadule Payal Arun , Soumia P. S. , Govindasamy Venkadasamy , Gawande Suresh Janardhan , Mahajan Vijay 
Published: July 2024

IntroductionThe application of mineral fertilizers deteriorates soil properties and affects crop yield and nutritional properties. However, plant growth-promoting microorganisms (PGPM- Serendipita indica, phosphorus solubilizing bacteria (PSB), and vesicular arbuscular mycorrhizae (VAM)) have great potential to reduce fertilizers and improve soil fertility, crop yield, and nutrient uptake and mitigate the environmental effect of mineral fertilizers.Material and methodsHence, a field experiment was conducted involving nine treatments to evaluate the effects of PGPM along with 50% or 100% of the recommended dose of fertilizers on plant growth, soil fertility, nutrient uptake, and onion productivity.Results and discussionResults indicated that 100% RDF combined with S. indica or PSB led to improved plant growth, and higher nutrient concentrations in both leaves and bulbs of onions compared to RDF alone. Moreover, the application of 100% RDF with S. indica increased total dry matter yield by 11.5% and 7.6% in the 2018-2019 and 2019-2020 seasons, respectively, compared to 100% RDF alone. This treatment also resulted in the highest nutrient uptake, with N uptake increasing by 6.9%-29.9%, P by 13.7%-21.7%, K by 20.0%-23.7%, and S by 18.1%-23.4%. Additionally, the combination of 100% RDF with S. indica inoculation led to a notable increase in bulb yield, with increments of 16.2% and 13.9% observed in 2018-2019 and 2019-2020, respectively, compared to 100% RDF alone. Similarly, the application of 100% RDF along with PSB inoculation resulted in an increase in bulb yield by 7.2% and 9.4% in the respective years. However, VAM did not exhibit satisfactory performance or improvements in the onion crop.ConclusionOverall, the study suggests that combining 100% RDF with S. indica or PSB can enhance onion productivity and nutrient use efficiency. The present study may open a new avenue of PGPM application in enhancing onion yield and improving the bulb quality as well as soil health. However, field trials across different regions and soil types are necessary to validate these findings for practical adoption by farmers.
Comparison between MRI FLAIR vascular hyperintensity-DWI mismatch and perfusion based triage for thrombectomy in the late time window
Authors: Luo Leilei , Zhou Guanen , Meng Fanlei , Liu Shuling , Wang Sifei , Dou Yuchao , Lu Da , Wei Ming 
Published: July 2024

BackgroundThe clinical impact of patient selection using FLAIR vascular hyperintensity (FVH)–diffusion-weighted imaging (DWI) mismatch for endovascular thrombectomy (EVT) in patients who have been symptomatic for over 6 h remains unclear. Herein, a retrospective study was conducted to compare the inter-rater reliability and clinical outcomes of patients selected for thrombectomy based on FVH-DWI mismatch with perfusion.MethodsPatients with anterior-circulation large-vessel occlusion selected simultaneously with MRI and perfusion imaging in the late time window from a single-center retrospective study were categorized into EVT-applicable (FVH-DWI mismatch on MRI or perfusion imaging meeting the DEFUSE3 standards) and EVT-inapplicable groups based on MRI and perfusion imaging. The primary outcome was the 90-day functional independence rate. Safety outcomes encompassed symptomatic intracranial hemorrhage and mortality in 90 days. We assessed the consistency of the two profiles and compared the differences in functional independence rates of EVT patients among the EVT-applicable groups determined by MRI and perfusion.ResultsA total of 130 patients were enrolled, of which 114 were classified into the EVT-applicable group after triaging using MRI images. In this group, 96 patients underwent EVT, with 53 of them (55.2%) achieving functional independence. A total of 110 patients were divided into EVT-applicable group based on perfusion, among which 92 underwent EVT, with 49 of them (53.2%) achieving functional independence. The consistency of identifying EVT indication was moderate between two groups (κ = 0.42, 95% CI, 0.17–0.67). The functional independence rate was comparable between patients in the two EVT-applicable groups based on the two methods (55.2% vs. 53.2%, p = 0.789).ConclusionMRI triaging based on FVH-DWI mismatch showed moderate inter-rater reliability compared with perfusion-based triage and comparable efficacy in predicting clinical outcomes after EVT.
Dietary inflammatory index and the risks of non-alcoholic fatty liver disease: a systematic review and meta-analysis
Authors: Zhang Xingfen , Ruan Jiale , He Yujing , Xu Anyi , Fang Yingying , Zhang Qiufeng , Gu Lihu , Liu Xingchen 
Published: July 2024

BackgroundPrevious studies have suggested a correlation between dietary inflammatory potential and non-alcoholic fatty liver disease (NAFLD). Therefore, the study aimed to investigate the association between dietary inflammatory potential, measured by the dietary inflammation index (DII), and NAFLD.MethodsFrom establishing the database to June 2023, a systematic search of PubMed, Web of Science, Embase and Cochrane Library were performed to identify relevant observational studies. These studies reported a correlation between DII and NAFLD. The meta-analysis used odds ratio (OR) with 95% confidence intervals (CI) to evaluate the relationship between DII and NAFLD.ResultsEight studies were included in this meta-analysis after excluding irrelevant records. A summary of the results from the included studies showed that the risk of NAFLD was higher in those exposed to higher DII (OR = 1.26, 95%CI 1.12 to 1.40, p &lt; 0.001), with a high degree of heterogeneity (I2 = 85.7%, p &lt; 0.001). When DII was divided into 3 tertiles from low to high for comparison, the results showed that the risk of NAFLD was higher in Tertile 2 (T2) population compared to the Tertile 1 (T1) population (OR = 1.75, 95%CI 1.20 to 2.54, p &lt; 0.005). The risk of NAFLD was significantly higher in Tertile 3 (T3) compared to the T1 population (OR = 3.07, 95%CI 1.63 to 5.77, p = 0.001).ConclusionThe results suggest that high DII is associated with an increased risk of NAFLD, and conversely, low DII is associated with a decreased risk of NAFLD.Systematic Review RegistrationThe study complies with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and is registered on PROSPERO (CRD42023455013).
Trabectedin may be a valuable treatment option for elderly patients with metastatic soft tissue sarcomas
Authors: Miolo Gianmaria , Buonadonna Angela , Lombardi Davide , Scalone Simona , Lauretta Andrea , Della Puppa Lara , Corona Giuseppe 
Published: July 2024

BackgroundIn the landscape of metastatic soft tissue sarcoma (mSTS) treatment, anthracyclines have shown efficacy; however, their associated toxicity imposes significant limitations, especially in frail elderly patients with mSTS who are highly susceptible to severe adverse effects. In this context, trabectedin, due to its distinct pharmacological profile and safety profile, may represent an interesting alternative being demonstrated to be active in treating mSTS. These features hold particular significance for elderly and unfit patients with mSTS, where balancing treatment benefits with potential adverse effects represents the pivotal objective.MethodsThe investigation was focused on a specific group of 11 elderly patients with mSTS aged ≥70, all undergoing first-line treatment with trabectedin, and it was supported by comprehensive pharmacokinetic and pharmacodynamic studies. Among these patients, 9 out of 11 started the treatment at a dose of 1.5 mg/m2.ResultsThe primary objective of this investigation is to highlight trabectedin as a valuable first-line treatment option for elderly and unfit patients with mSTS. Additionally, this investigation seeks to explore whether higher administered doses of trabectedin can enhance clinical outcomes while maintaining the same toxicity profiles. The median progression-free survival (PFS) was 77 days (95% CI, 53–89), the median overall survival (OS) was 397 days (95% CI, 66–2,102), while the overall toxicity of grade 3–4 severity amounted to 43%.ConclusionThese findings provide new insights into the clinical outcomes and toxicity associated with trabectedin in an elderly patient population, enhancing our understanding of better treatment approaches for a specific population of patients with mSTS.
The development of prosodic focus marking in French
Authors: Destruel Emilie , Lalande Louise , Chen Aoju 
Published: July 2024

IntroductionFrench is traditionally described as a language favoring syntactic means to mark focus, yet recent research shows that prosody is also used. We examine how French-speaking children use prosody to realize narrow focus and contrastive focus in the absence of syntactic means, compared to adults.MethodWe elicited SVO sentences using a virtual robot-mediated picture-matching task from monolingual French-speaking adults (N = 11), 4- to 5-year-olds (N = 12), and 7- to 8-year-olds (N = 15). These sentences were produced with narrow focus on either the subject or the object and contrastive focus on the object.ResultsLinear mixed-effects logistic regression modeling on duration, mean intensity, mean pitch, and pitch range of the subject and object nouns showed that the 4- to 5-year-olds did not use any of these prosodic cues for focus marking but the 7- to 8-year-olds distinguished narrow focus from non-focus through an increase in duration, mean intensity and to a lesser degree, mean pitch in the object nouns, largely similar to the adults, and tended to use mean pitch for this purpose in the subject nouns, different from the adults, who used duration.DiscussionOur study corroborates previous findings that French-speaking 4- to 5-year-olds do not use prosody for focus. Further, it provides new evidence that 7- to 8-year-olds use prosody to mark narrow focus on the object in a more adult-like manner than narrow focus on the subject, arguably caused by a more dominant role of syntactic means in the subject position in French. Together, these findings show that syntax-dominance can influence both the route and the rate of acquisition of prosodic focus marking.
A brief research report of suicide rates in the Brazilian elderly over a 12-year period: the lack of association of the "Setembro Amarelo" campaign for suicide prevention
Authors: Corrêa Matias Pereira Camila , Najafi Moghaddam Gilani Vahid , Nazif-Munoz José Ignacio 
Published: July 2024

ObjectivesAiming to disseminate information related to suicide prevention in Brazil, the “Setembro Amarelo” campaign has been conducted since 2015. The objective of this study is to assess the association between this campaign and elderly suicide rates over a 12-year period.MethodsData were gathered from the Mortality Information System and the Notifiable Diseases Information System, established by public institutions in Brazil. An interrupted time-series framework was applied to assess the association between the “Setembro Amarelo” campaign and suicide mortality rates in the elderly population (60 et plus) in the southeastern region of Brazil. We consider three monthly outcomes: all suicides, suicides in males and suicide in females. We operationalize the campaign assuming three effects: short-term, declining and sustained. The period of analysis was from 2011-2022.ResultsThe suicide-mortality rate over time has remained stable; the average rate in the pre-campaign period was 0.028 and increased slightly to 0.035. Regardless of the campaign’s operationalization and the outcome used, results show no significant associations between the campaign and elderly suicide rates. The campaign was associated with non-significant decreased effects of 15% (P=0.532) in the short term, and 16% (P=0.446) assuming the campaign was sustained.ConclusionsThere is a lack of association between the campaign and suicide rates, among the elderly in Brazil’s southeastern region. As suicide is complex and multifactorial, more research is needed. The campaign, while raising awareness and reducing stigma, may not reduce suicides. To reduce the suicide rate in the elderly requires addressing social, economic and cultural factors, multisectoral interventions, and upholding basic human rights.
Doctor AI? A pilot study examining responses of artificial intelligence to common questions asked by geriatric patients
Authors: Moore Ian , Magnante Christopher , Embry Ellie , Mathis Jennifer , Mooney Scott , Haj-Hassan Shereen , Cottingham Maria , Padala Prasad R. 
Published: July 2024

IntroductionAI technologies have the potential to transform patient care. AI has been used to aid in differential diagnosis and treatment planning for psychiatric disorders, administer therapeutic protocols, assist with interpretation of cognitive testing, and patient treatment planning. Despite advancements, AI has notable limitations and remains understudied and further research on its strengths and limitations in patient care is required. This study explored the responses of AI (Chat-GPT 3.5) and trained clinicians to commonly asked patient questions.MethodsThree clinicians and AI provided responses to five dementia/geriatric healthcare-related questions. Responses were analyzed by a fourth, blinded clinician for clarity, accuracy, relevance, depth, and ease of understanding and to determine which response was AI generated.ResultsAI responses were rated highest in ease of understanding and depth across all responses and tied for first for clarity, accuracy, and relevance. The rating for AI generated responses was 4.6/5 (SD = 0.26); the clinician s' responses were 4.3 (SD = 0.67), 4.2 (SD = 0.52), and 3.9 (SD = 0.59), respectively. The AI generated answers were identified in 4/5 instances.ConclusionsAI responses were rated more highly and consistently on each question individually and overall than clinician answers demonstrating that AI could produce good responses to potential patient questions. However, AI responses were easily distinguishable from those of clinicians. Although AI has the potential to positively impact healthcare, concerns are raised regarding difficulties discerning AI from human generated material, the increased potential for proliferation of misinformation, data security concerns, and more.
Aftercare Provision for Bereaved Relatives Following Euthanasia or Physician-Assisted Suicide: A Cross-Sectional Questionnaire Study Among Physicians
Authors: Renckens Sophie C. , Pasman H. Roeline , van der Heide Agnes , Onwuteaka-Philipsen Bregje D. 
Published: July 2024

Objectives: Relatives of patients who died after euthanasia or physician-assisted suicide (EAS) might need (specific) aftercare. We examined if and how physicians provide aftercare to bereaved relatives of patients who died after EAS, and which patient-, physician- and process characteristics are associated with providing aftercare.Methods: A cross-sectional questionnaire study was conducted among 127 physicians (general practitioners, clinical specialists, and elderly care physicians) in the Netherlands. Associations were examined using multivariable logistic regression analyses.Results: Most physicians had had at least one follow-up conversation with bereaved relatives (77.2%). Clinical specialists less often provided aftercare compared to GPs. Also, aftercare was more often provided when the deceased had a cohabiting partner. Topics addressed during aftercare conversations included looking back on practical aspects of the EAS trajectory, the emotional experience of relatives during the EAS trajectory and relatives’ current mental wellbeing. A minority of aftercare conversations led to referral to additional care (6.3%).Conclusion: Aftercare conversations with a physician covering a wide-range of topics are likely to be valuable for all bereaved relatives, and not just for “at risk” populations typically targeted by policies and guidelines.
O impacto das características do cimento biocerâmico reparador Bio-C Repair frente à microcirurgia endodôntica: relato de caso clínico
Authors: Melo Maria José Lopes de , Souza Ana Clara Pereira de , Marques Daniella Bitone Pinheiro , Francisco Everton Mateus Pina , Cotrim Laila Teixeira , Cruz Leonardo Pereira da , Souza Michele Silva , Lima Vivine Silva 
Published: July 2024

Diante de um insucesso endodôntico é plausível abordar outras formas de intervenção que viabilizem a cura dos tecidos periapicais, facilitando o desaparecimento dos sinais e sintomas e consequentemente a satisfação do paciente. A cirurgia endodôntica é um procedimento seguro e efetivo, com capacidade de tratamento de infecções intracanal e extrarradicular, principalmente aliado a materiais biocompatíveis. O objetivo deste estudo foi avaliar in vivo a influência do cimento reparador biocerâmico Bio-C Repair na regeneração dos tecidos perirradiculares. Este trabalho descreve o caso clínico no elemento dental 15, após a realização da cirurgia parendodôntica por insucesso no tratamento endodôntico convencional. Paciente do sexo feminino, procurou tratamento devido a uma ferida que não cicatrizava na gengiva próxima ao ápice do elemento 15, mesmo após ter realizado o tratamento endodôntico convencional e uma segunda reintervenção, apresentava sintomatologia dolorosa. Durante a anamnese não foi constatado nenhum comprometimento sistêmico. No exame físico foi relatado sintomatologia dolorosa à palpação apical, percussão vertical e apresentava-se com fístula próximo ao ápice do elemento 15. No exame de imagem tanto radiográfico quanto tomográfico, foi detectada tratamento endodôntico satisfatório, entretanto, uma extensa lesão radiolúcida circunscrita na região periapical do elemento 15. O tratamento proposto foi a cirurgia parendodôntica, com a utilização de um material biocerâmico relativamente novo no mercado, o Bio-C Repair. O caso foi acompanhado clínico e radiograficamente durante nove meses. Após três meses, notou-se, melhora dos sinais clínicos e radiograficamente leve esfumaçamento da lesão perirradicular. Após nove meses, na tomografia computadorizada de feixe cônico, observou a regeneração dos tecidos perirradiculares, o que compactua com as propriedades proposta pelo fabricante do Bio-C Repair e com os estudos clínicos já embasados na literatura científica.
Algorithm for Managing Staff Development on Enterprises
Authors: Паршина В.С. 
Published: July 2024

Статья посвящена формированию системного подхода к управлению развитием персонала на микроуровне с зависимости от изменения факторов внешней и внутренней хозяйственной среды, а также учета инициаторов развития. Предложена систематизация алгоритмов организации процессов развития работников на микроуровне на основе идентификации состояния внешней и внутренней среды, а также соотношения фактических качественных характеристик персонала относительно востребованных, которые в совокупности обусловливают методы управляющих воздействий. Обоснованы варианты алгоритмов управления развитием кадров.
The article is devoted to the formation of a systematic approach to the study of personnel development at the micro level, depending on changes of the factors in external and internal environment, as well as taking into account the mutual interests of the parties. A systematization of algorithms for organizing the processes of employee development at the micro level is proposed based on the identification of the state of the external and internal environment, as well as assessing the actual state of the qualitative characteristics of the personnel with respect to demand, which together determine the methods of control actions. Variants of control actions algorithms are substantiated.
Assessment of the Socio-economic Condition of the Peoples of the Countries of Different Level of Development
Authors: Хисаева А.И. , Ишмухаметов Э.М. , Хисаева А.И. , Гайсина Р.Р. 
Published: July 2024

В статье изложена оценка социально-экономического состояния трех групп стран Золотого миллиарда , развивающихся и так называемых неприсоединившихся стран. При анализе состояния уровня развития использованы качественные категории, переведенные в цифровую форму коэффициентов энтропии. Применена разновидность метода расчета меры хаоса-энтропии для оценки социально-экономического состояния народов. В работе качественные категории показателей энтропии переведены в цифровую форму индексов стандартным методом нормирования для ее компьютерного решения на программе Mathcad .
The article presents an assessment of the socio-economic status of three groups of countries the Golden Billion , developing and so-called non-aligned countries. When analyzing the state of the development level, qualitative categories were used that were digitized in the entropy coefficients. A variety of the method for calculating the measure of chaos-entropy is applied to assess the socio-economic status of peoples. In the work, the qualitative categories of entropy indices are digitized by the standard standardization method for its computer solution using the Mathcad program.
Islamic Finance Innovations
Authors: Азнабаева Г.Х. , Вакушина А.А. , Ветошкина В.А. , Давлетгареев Р.Ф. 
Published: July 2024

В статье рассмотрены пути внедрения инноваций в сфере исламских финансов, которые не должны противоречить шариату. Исламское финансирование сталкивается с особенными проблемами, поскольку оно интегрируется в цифровую эпоху, регулирующие органы полны решимости сделать этот переход для современного развития системы.
The article discusses the ways of introducing innovations in Islamic finance, which should not contradict Sharia. Islamic finance faces particular challenges as it integrates into the digital age, regulators are determined to make this transition for the modern development of the system.
Socio-Economic Contradictions of Consumer Demand in the Conditions of the Economy of the Information Society
Authors: Сафиуллина Евгения Александровна 
Published: July 2024

В статье определены основные социально-экономические противоречия потребительского спроса в ус- ловиях развития экономики информационного общества. Выявлено, что характерной чертой экономики информационного общества становится своеобразная форма социальной организации, в которой с по- мощью информационно-коммуникационных технологий происходит аккумулирование информации, об- работка и ее внедрение во сферы жизни. Предложены основные меры для решения проблемы диффе- ренциации доходов самых богатых и бедных слоев населения с целью стимулирования потребительско- го спроса.
The article identifies the main socio-economic contradictions of consumer demand in the context of the development of the economy of the information society. It has been revealed that a characteristic feature of the economy of the information society is a peculiar form of social organization, in which, with the help of information and communication technologies, information is accumulated, processed and introduced into the realm of life. The basic measures for the solution of the problem of income differentiation of the richest and poorest segments of the population are proposed.
Improving the Sales Process Management Methodology
Authors: Барлыбаев У.А. , Вавилова Е.А. 
Published: July 2024

В статье представлен методический подход к управлению сбытовой деятельностью компании, позволяющий скоординировать цель и задачи всех подразделений, переориентировать их деятельность на рыночные потребности покупателей и конечные результаты деятельности компании.
The article presents a methodological approach to managing the company's sales activities, which allows you to coordinate the goals and objectives of all divisions and reorient their activities to the market needs of customers and the final results of the company's activities.