bluuebunny/crossref_metadata_2025_split huggingface dataset:
On the realization of a class of $\text{SL}(2,\mathbb{Z})$ representations
Authors: Yu Zhiqiang 
Published: June 2024

Let

p<q

be odd primes and

\rho_{1}

and

\rho_{2}

be irreducible representations of

\text{SL}(2,\mathbb{Z}_{p})

and

\text{SL}(2,\mathbb{Z}_{q})

of dimensions

\frac{p+1}{2}

and

\frac{q+1}{2}

, respectively. We show that if

\rho_{1}\oplus\rho_{2}

can be realized as a modular representation associated with a modular fusion category

\mathcal{C}

, then

q-p=4

. Moreover, if

\mathcal{C}

contains a non-trivial étale algebra, then

\mathcal{C}\boxtimes\mathcal{C}(\mathbb{Z}_{p},\eta)\cong\mathcal{Z}(\mathcal{A})

as a braided fusion category, where

\mathcal{A}

is a near-group fusion category of type

(\mathbb{Z}_{p},p)

, which gives a partial answer to the conjecture of D. Evans and T. Gannon. We also show that there exists a non-trivial

\mathbb{Z}_{2}

-extension of

\mathcal{A}

that contains simple objects of Frobenius–Perron dimension

\frac{\sqrt{p}+\sqrt{q}}{2}

.
Safety and efficiency of Wharton’s Jelly-derived mesenchymal stem cell administration in patients with traumatic brain injury: First results of a phase I study
Authors: Kabatas Serdar , Civelek Erdinç , Boyalı Osman , Sezen Gülseli Berivan , Ozdemir Omer , Bahar-Ozdemir Yeliz , Kaplan Necati , Savrunlu Eyüp Can , Karaöz Erdal 
Published: June 2024

BACKGROUND
Traumatic brain injury (TBI) is characterized by a disruption in the normal function of the brain due to an injury following a trauma, which can potentially cause severe physical, cognitive, and emotional impairment. Stem cell transplantation has evolved as a novel treatment modality in the management of TBI, as it has the potential to arrest the degeneration and promote regeneration of new cells in the brain. Wharton’s Jelly-derived mesenchymal stem cells (WJ-MSCs) have recently shown beneficial effects in the functional recovery of neurological deficits.
AIM
To evaluate the safety and efficiency of MSC therapy in TBI.
METHODS
We present 6 patients, 4 male and 2 female aged between 21 and 27 years who suffered a TBI. These 6 patients underwent 6 doses of intrathecal, intramuscular (i.m.) and intravenous transplantation of WJ-MSCs at a target dose of 1 × 106/kg for each application route. Spasticity was assessed using the Modified Ashworth scale (MAS), motor function according to the Medical Research Council Muscle Strength Scale, quality of life was assessed by the Functional Independence Measure (FIM) scale and Karnofsky Performance Status scale.
RESULTS
Our patients showed only early, transient complications, such as subfebrile fever, mild headache, and muscle pain due to i.m. injection, which resolved within 24 h. During the one year follow-up, no other safety issues or adverse events were reported. These 6 patients showed improvements in their cognitive abilities, muscle spasticity, muscle strength, performance scores and fine motor skills when compared before and after the intervention. MAS values, which we used to assess spasticity, were observed to statistically significantly decrease for both left and right sides (P < 0.001). The FIM scale includes both motor scores (P < 0.05) and cognitive scores (P < 0.001) and showed a significant increase in pretest posttest analyses. The difference observed in the participants’ Karnofsky Performance Scale values pre and post the intervention was statistically significant (P < 0.001).
CONCLUSION
This study showed that cell transplantation has a safe, effective and promising future in the management of TBI.
RPLP0/TBP are the most stable reference genes for human dental pulp stem cells under osteogenic differentiation
Authors: Ferreira Daniel B , Gasparoni Leticia M , Bronzeri Cristiane F , Paiva Katiucia B S 
Published: June 2024

BACKGROUND
Validation of the reference gene (RG) stability during experimental analyses is essential for correct quantitative real-time polymerase chain reaction (RT-qPCR) data normalisation. Commonly, in an unreliable way, several studies use genes involved in essential cellular functions [glyceraldehyde-3-phosphate dehydrogenase (GAPDH), 18S rRNA, and β-actin] without paying attention to whether they are suitable for such experimental conditions or the reason for choosing such genes. Furthermore, such studies use only one gene when Minimum Information for Publication of Quantitative Real-Time PCR Experiments guidelines recommend two or more genes. It impacts the credibility of these studies and causes distortions in the gene expression findings. For tissue engineering, the accuracy of gene expression drives the best experimental or therapeutical approaches.
AIM
To verify the most stable RG during osteogenic differentiation of human dental pulp stem cells (DPSCs) by RT-qPCR.
METHODS
We cultivated DPSCs under two conditions: Undifferentiated and osteogenic differentiation, both for 35 d. We evaluated the gene expression of 10 candidates for RGs [ribosomal protein, large, P0 (RPLP0 ), TATA-binding protein (TBP ), GAPDH , actin beta (ACTB ), tubulin (TUB ), aminolevulinic acid synthase 1 (ALAS1 ), tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta (YWHAZ ), eukaryotic translational elongation factor 1 alpha (EF1a ), succinate dehydrogenase complex, subunit A, flavoprotein (SDHA ), and beta-2-microglobulin (B2M )] every 7 d (1, 7, 14, 21, 28, and 35 d) by RT-qPCR. The data were analysed by the four main algorithms, ΔCt method, geNorm, NormFinder, and BestKeeper and ranked by the RefFinder method. We subdivided the samples into eight subgroups.
RESULTS
All of the data sets from clonogenic and osteogenic samples were analysed using the RefFinder algorithm. The final ranking showed RPLP0/TBP as the two most stable RGs and TUB/B2M as the two least stable RGs. Either the ΔCt method or NormFinder analysis showed TBP/RPLP0 as the two most stable genes. However, geNorm analysis showed RPLP0/EF1α in the first place. These algorithms’ two least stable RGs were B2M/GAPDH. For BestKeeper, ALAS1 was ranked as the most stable RG, and SDHA as the least stable RG. The pair RPLP0/TBP was detected in most subgroups as the most stable RGs, following the RefFinfer ranking.
CONCLUSION
For the first time, we show that RPLP0/TBP are the most stable RGs, whereas TUB/B2M are unstable RGs for long-term osteogenic differentiation of human DPSCs in traditional monolayers.
Effect Modification of Heat-Related Mortality Risk by Air Pollutants in Shandong, China
Authors: Zhao Zhonghui , Chu Jie , Ren Jie , Xu Chunxiao , Xu Xiaohui , Cao Yanwen , Schikowski Tamara , Zhao Qi , Liu Qiyong , Chen Gongbo , Lu Zilong , Guo Xiaolei , Ma Wei , Wang Haitao , Ma Jixiang 
Published: June 2024

ABSTRACT.
Although studies have reported the modification effect of air pollutants on heat-related health risk, little is known on the modification effect among various particulate matter with different particle size on mortality. We aimed to investigate whether the associations of hot temperatures with daily mortality were modified by different air pollutant levels in Shandong Province, China. Daily data of air pollutants, meteorological factors, and mortality of 1,822 subdistricts in Shandong province from 2013 to 2018 were collected. We used a time-stratified case-crossover model with an interaction term between the cross-basis term for ambient temperature and the linear function of particulate matter ≤1 µm (PM1), PM2.5, nitrogen dioxide (NO2), and ozone to obtain heat-mortality associations during the hot season. Results showed that the cumulative odds ratio of extreme heat on mortality over 0 to 10 days was 3.66 (95% CI: 3.10–4.31). The mortality risk during hot seasons was stronger at high air pollutant levels. The modification effect of particulate matters on heat-related mortality decreased by its aerodynamic diameter. Females and older adults over 75 years were more vulnerable to the modification effect of air pollutants, and significant differences were detected in the association between temperatures and mortality stratified by PM1 and PM2.5. Higher heat-related mortality risks were observed at high NO2 levels, especially for cardiorespiratory disease. The findings suggest that more consideration should be given to the combined effect of very fine particles and NO2 with ambient heat when developing healthcare strategies, and women and older adults should be given priority in health-related settings.
Self-Rated Competence of Ugandan Healthcare Workers to Obtain Informed Consent for Autopsy
Authors: Bongomin Felix , Kibone Winnie , Nantale Ritah , Lukande Robert , Bromley Ruth , Muzoora Conrad , Hamer Davidson H. 
Published: June 2024

ABSTRACT.
We examined the self-rated competence of Ugandan healthcare workers (HCWs) in obtaining informed consent for autopsies, considering the challenges of low autopsy acceptance rates globally. In September and October 2023, we conducted a nationwide cross-sectional study of HCWs, who provided informed consent to participate and completed an online, self-administered questionnaire. Participants’ self-rated competence in obtaining informed consent for autopsy was assessed through Likert scale questions. Knowledge and practices were also assessed. All scores were converted to percentages, with scores ≥80% indicating higher competence. We enrolled 216 HCWs (including 145 [67.1%] doctors), with a mean age of 31.6 ± 7.2 years. Overall, 55.6% (n = 120) had ever assisted in obtaining consent for autopsy, 43.6% (n = 100) had ever obtained consent for autopsy themselves, and 13.4% (n = 29) had ever attended training on obtaining consent for autopsy. The mean competency score was 59.8 ± 17.0% (perfect score, 100%), with 29 (13.4%) participants demonstrating high competence. Healthcare workers with adequate knowledge had higher competence scores (odds ratio [OR]: 15.0, 95% CI: 6.17–36.58, P <0.001). Compared with nurses/midwives, doctors had 73% lower odds of having a high competence score (adjusted OR: 0.27, 95% CI: 0.08–0.94, P = 0.040). Fewer than one in five Ugandan HCWs demonstrated high self-rated competence or possessed adequate knowledge regarding informed consent for autopsies, and only a few had received specialized training on how to obtain consent for an autopsy. Therefore, there is a pressing need for enhanced training and increased awareness among Ugandan HCWs in obtaining informed consent for autopsies.
Isolation and Growth Kinetics of Bogoria Virus from Phlebotomine Sandflies Sampled in Baringo, Kenya
Authors: Thiiru Jane Wambui , Langat Solomon , Mulwa Francis , Cinkovich Stephanie , Koka Hellen , Yalwala Santos , Khamadi Samoel , Onguso Justus , Odemba Nicholas , Ngere Francis , Johnson Jaree , Egbo Timothy , Garges Eric , Ojwang Elly , Eyase Fredrick 
Published: June 2024

ABSTRACT.
Phleboviruses are an emerging threat to public health. Recent surveillance efforts in Kenya have unveiled novel phleboviruses. Despite these efforts, there remain knowledge gaps. This study tested female sandflies from diverse ecological settings in Kenya for arboviruses. Sandfly pools were cultured in Vero-CCL cells. Pools showing reproducible cytopathic effects were subjected to next-generation sequencing, followed by phylogenetic analysis. In vitro, cell kinetics analysis was performed using both Vero-E6 cells and C6/36 mosquito cells. One pool from Baringo, Kenya, tested positive for Bogoria virus (BOGV). The BOGV genome clustered in a single clade with previously obtained BOGV genomes. No significant differences were observed between Vero and C6/36 cell growth kinetics. This study has confirmed the presence of BOGV among sandflies in Baringo Kenya and demonstrated growth in mosquito cells.
Design of an efficient energy based dual level co-operative route protocols in multiple hop WSNs
Authors: Hanumanthappa S.N  , Dr. Girish V. Attimarad  
Published: June 2024

The design and implementation of an energy efficient dual stage cooperative routing protocol (DSCR) in multiple hop wireless nets is discussed in this paper in brief, with the goal of improving network life-time, boosting dependability, and reducing energy consumption. This contribution’s major goal is to propose an enhanced version of the double stage data transfer system that computes the routing path utilizing cooperative mechanisms and the notion of reduced node energy. The work presented here also includes talks, discussion and graphical representations of the various outcomes achieved for all of the test scenarios, as well as the relevant observations and explanations. The research paper comes to a close with the multiple hop networks’ overall conclusions remarks.
Federal project “Professionalitet” — new opportunities for the development of an educational organization
Authors: Soimina T. V. , Svetlichnaya E. A. 
Published: June 2024

The results of activities, prospects and opportunities for the development of educational and production centers (clusters) of railway transport during the implementation of the federal project “Professionalitet” are analyzed.The purpose of the study is to assess the development opportunities of educational organizations participating in the implementation of the federal project “Professionalitet”, as well as to broadcast the experience of participation in the project of the Yaroslavl branch of PGUPS.
Mortality rates for men and women from cerebrovascular and nervous diseases in the regions of Russia in 2013 and 2022
Authors: Kakorina E. P. , Samorodskaya I. V. , Kotov S. V. 
Published: June 2024

In recent years, researchers have noted an increase in mortality from neurodegenerative diseases and a decrease in mortality from strokes. There have been no studies comparing mortality from these causes in the regions of the Russian Federation.Aim:comparative analysis of regional (age-) standardized death rate (SDR) among men and women from cerebrovascular diseases (CVD) and nervous system diseases (NSD) in 2013 and 2022 and discussion of factors influencing SDR.Materials and methods.Rosstat data obtained upon request were used. SDR was calculated using software (state registration number of computer program 216661114) using the European Standard Population using the direct standardization method per 100 thousand population; The average regional SDR values were calculated for the class of NSD and individual groups from this class, CVB (codes I60–69).Results.A decrease in the regional average SDR from CVD was revealed among men (218.09 ± 60.81 in 2013 and 159.41 ± 51.20 per 100 thousand people in 2022) and women (144.30 ± 39.33 and 103.51 ± 32.63 respectively) and the increase in SDR from LBP (19.77 ± 17.70 and 65.99 ± 56.67 for men, 10.99 ± 11.32 and 52.81 ± 46.13 for women). Only in 4 regions was there a decrease in SDR from both NSD and CVD in both men and women. The dispersion of regional SDRs from NSD and CVB in 2022 compared to 2013 increased by more than 10 times, which indicates a significant and growing regional variability of indicators. In the stroke group, the most significant decrease occurred from “Stroke not specified as hemorrhage or infarction” (code I64). The regional average contribution of acute stroke (codes I60–64) to the SCS from NSD and CVB (in total) decreased (in 2013 among women 51.57 ± 16.26 %, in 2022 33.96 ± 14.95 %; among men 54.0 ± 15.01 and 39.82 ± 14.26 respectively). Alzheimer’s disease makes a negligible contribution to mortality; In men in certain regions, alcohol-associated LBP is significant.Conclusions.Significant regional variability of SDR from individual groups of causes and a general trend towards a decrease in SDR from CVD and an increase in SDR from NSD were revealed, which is due to many factors. To eliminate the influence of different approaches to determining the cause of death, a unified protocol of criteria for their establishment is necessary.
SPIRITUAL WELL BEING DENGAN KUALITAS HIDUP PASIEN TUBERKULOSIS PARU
Authors: Ifa Nofalia  , Wibowo Suhendra 
Published: June 2024

Tuberkulosis paru (TB paru) merupakan penyakit menular kronis yang berdampak signifikan pada berbagai aspek kehidupan pasien. Banyaknya dampak yang terjadi akan menyebabkan penurunan pada kualitas hidup pasien. Spiritual well-being dapat membuat seseorang menerima kondisi yang terjadi padanya sehingga diharapkan meningkatkan kualitas hidup. Tujuan penelitian ini adalah untuk mengetahui hubungan spiritual well-being dengan kualitas hidup pada pasien TB paru di Kecamatan Peterongan Kabupaten Jombang. Penelitian ini menggunakan metode kuantitatif observasional analitik dengan pendekatan cross sectional. Populasi dalam penelitian ini berjumlah 192 pasien dengan sampel 130 responden dengan penarikan menggunakan teknik simple random sampling. Kuisioner Spiritual Well Being Scale (SWBS) digunakan untuk menilai spiritual well-being dan World Health Organization Quality Of Life – BREF (WHOQOL-BREF) untuk mengukur kualitas hidup pada pasien. Metode analisis data yang digunakan adalah dengan menggunakan uji spearman rank. Hasil penelitian menunjukkan 57% responden memiliki tingkat spiritual well being tinggi. Sebanyak 61% responden memiliki kualitas hidup tinggi. Hasil uji korelasi spearman rank menunjukkan ada hubungan antara spiritual well being dengan kualitas hidup pada pasien tuberkulosis paru (p= 0,001). Oleh karena itu dalam memberikan asuhan keperawatan pada pasien tuberkulosis paru perlu diberikan intervensi untuk meningkatkan spiritual well-being sehingga kualitas hidup juga meningkat.

Pulmonary tuberculosis (pulmonary TB) is a chronic infectious disease that significantly impacts various aspects of patients' lives. The numerous effects of the disease can lead to a decrease in patients' quality of life. Spiritual well-being can help individuals accept their condition, improving their quality of life. This study aims to determine the relationship between spiritual well-being and quality of life in pulmonary TB patients in Peterongan District, Jombang Regency. This research employs a quantitative observational analytic method with a cross-sectional approach. The population in this study consisted of 192 patients, with a sample of 130 respondents selected using simple random sampling. The Spiritual Well-Being Scale (SWBS) was used to assess spiritual well-being, and the World Health Organization Quality Of Life – BREF (WHOQOL-BREF) was used to measure the quality of life in patients. Data analysis was conducted using the Spearman rank test. The results showed that 57% of respondents had a high level of spiritual well-being, and 61% had a high quality of life. The Spearman rank correlation test results indicated a relationship between spiritual well-being and quality of life in pulmonary TB patients (p=0.001). Therefore, nursing care for pulmonary TB patients should include interventions to enhance their spiritual well-being and improve their quality of life.
COGNITIVE BEHAVIOR THERAPY MENURUNKAN GEJALA DEPRESI PADA IBU POSTPARTUM
Authors: Muspitha Fitri Dia , Rophi Kristiyani Herda 
Published: June 2024

Depresi postpartum merupakan sebuah gangguan mood yang dapat terjadi antara 2-6 minggu setelah melahirkan dan dapat berlangsung hingga satu tahun. Gangguan ini dapat mempengaruhi kesehatan fisik dan psikologis pada ibu dan bayi. Salah satu intervensi yang efektif dalam mengurangi gejala depresi postpartum adalah Cognitive Behavior Therapy (CBT). CBT dapat mengatasi pola pikir dan perilaku yang tidak sehat, dengan penekanan pada keyakinan budaya tentang peran ibu. Penelitian ini bertujuan untuk menguji pengaruh CBT terhadap gejala depresi postpartun. Metode penelitian ini menggunakan desain quasi experiment dengan pre and post test one group without control group di Puskesmas Arso III, Kabupaten Keerom, Papua. Sampel penelitian berjumlah 20 responden yang dipilih dengan teknik purposive sampling. Pengukuran depresi postpartum menggunakan Edinburg postpartum depression scale (EPDS). Hasil penelitian menunjukan rata-rata skor depresi postpartum sebelum diberikan intervensi CBT adalah 11,4±0,5. Setelah diberikan intervensi CBT terjadi penurunan rata-rata skor depresi postpartum menjadi 7,0±0,79 (penurunan 4,4 poin). Hasil uji wilcoxon menunjukkan nilai p= 0,000, yang berarti penurunan skor depresi postpartum signifikan secara statistik. Terapi CBT dapat dilakukan untuk meningkatkan kesehatan fisik dan psikologis pada ibu dan bayi.

Postpartum depression is a mood disorder that can occur between 2 to 6 weeks after childbirth and may last up to 1 year. This disorder can affect the physical and psychological health of both the mother and the baby. One effective intervention for reducing postpartum depression symptoms is Cognitive Behavior Therapy (CBT). CBT can address unhealthy thought patterns and behaviors, with an emphasis on cultural beliefs about the role of the mother. This study aims to examine the effect of CBT on postpartum depression symptoms. This study uses a quasi-experimental design with pre-test and post-test in one group without a control group at Puskesmas Arso III, Keerom Regency, Papua. The sample consisted of 20 respondents selected using purposive sampling. Postpartum depression was measured using the Edinburgh Postpartum Depression Scale (EPDS). The results showed that the average postpartum depression score before the CBT intervention was 11.4±0.5. After the CBT intervention, the average postpartum depression score decreased to 7.0±0.79 (a reduction of 4.4 points). The Wilcoxon test results showed a p-value of 0.000, indicating that the decrease in postpartum depression scores was statistically significant. CBT can be implemented to improve both mother and baby's physical and psychological health.
Analisa Pengambilan Keputusan Pemilihan Venodr Seragam Dengen Merode Analytical Hierarchy Proces (AHP) ( Studi Kasus General Affairs PT Penjallindo Nusantara)
Authors: Imas Widowati  , Daisy Ade Riany Diem  , Wanwan Jamaludin  , Eka Sukmawati Sukma  
Published: June 2024

Decision makers need analytical tools that allow them to solve problems. Decisions to be taken are complex with major risks such as policy formulation, decision makers often need tools in scientific, logical, and structured forms. To determine the priority stages of criteria in order to obtain the most optimal results in returning uniform vendor selection decisions at PT Penjalindo Nusantara (Metaform) using the AHP (Analytical Hierarchy Process) method. In essence, AHP is a comprehensive decision-making model by taking into account qualitative and quantitative matters. There are three main principles in problem solving in AHP, namely: Decomposition, Comparative Judgment, and Logical Concistency. Bycomparing in pairs to determine the priority weight on each criterion and alternative. One of the paired comparisons is carried out in pairwise comparisons between criteria. Vendor selection criteria include quality, price, flexibility, delivery and service criteria. . Compiling alternatives that have been determined in the form of matirx in order to obtain the assessment weight of each variable, a table of pair comparison rating scales is made. Based on the results of the AHP calculation, each weight for each venodr is obtained PT Intan of 0.62860 and the weight value of the Super Decision is 0.638683. PT Parahita as a vendor with a weight value of 0.20475 and a weight value in Super Decision of 0.203985. PT Marcapada with a weight value of 0.16665 and a weight value in Super Decision of 0.159189. So the main uniform supplier is PT Intan with the largest weight.