bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of Novel Dinuclear Cisplatinum(II) Complexes on the Electrical Properties of Human Molt-4 Leukemia Cells
Authors: Dobrzyńska Izabela , Skrzydlewska Elżbieta , Figaszewski Zbigniew A. 
Published: November 2014

AbstractThe aim of this study was to determine the influence of cisplatin and novel dinuclear platinum(II) complexes on the membrane electrical properties and lipid peroxidation levels of the Molt-4 human leukemia cell line. Changes in cell function may affect the basal electrical surface properties of cell membranes. These changes can be detected using electrokinetic measurements. Surface charge densities of Molt-4 cells were measured as a function of pH. A four-component equilibrium model was used to describe the interaction between the ions in solution and on cell membrane surfaces. Agreement was found between the experimental and theoretical charge variation curves of the leukemia cells at pH 2.5–9. Lipid peroxidation was estimated by measuring levels of 8-iso-prostaglandine F2α [isoprostanes]. Acid and base functional group concentrations and average association constants with hydroxyl ions were smaller in cisplatin- or dinuclear platinum(II) complex-treated leukemia cell membranes compared to those in untreated cancer cells, and the average association constants with hydrogen ions were higher. Levels of lipid peroxidation products in cisplatin- or dinuclear platinum(II) complex-treated leukemia cell were higher than those found in untreated cancer cells.
The role of feared possible selves in the relationship between peer influence and delinquency
Authors: Pierce Jennifer , Schmidt Carissa , Stoddard Sarah A. 
Published: November 2014

ABSTRACTThis study explores the impact of a feared delinquent possible self on the relationship between exposure to negative peer behaviors and violent and non‐violent self‐reported delinquency. Previous research strongly supports that deviant peers influence adolescents' delinquent behavior. Yet, few studies have explored intrapersonal factors that may moderate this influence. Possible selves include what one hopes, expects and fears becoming and are believed to motivate behavior. Thus, it was hypothesized that adolescents who were exposed to deviant peers and also feared engaging in delinquency would be more likely to self‐report delinquency. Seventh grade students (n = 176) identified feared possible selves in the future, their exposure to negative peer behavior and self‐reported violent and non‐violent delinquent behavior. Findings suggest that exposure to negative peer behavior is associated with self‐reported delinquent behavior. For violent behavior, possessing a feared delinquent possible self moderates this relationship. Implications and suggestions for future research are discussed.
Assessing cognition and function in Alzheimer's disease clinical trials: Do we have the right tools?
Authors: Snyder Peter J. , Kahle‐Wrobleski Kristin , Brannan Stephen , Miller David S. , Schindler Rachel J. , DeSanti Susan , Ryan J. Michael , Morrison Glenn , Grundman Michael , Chandler Julie , Caselli Richard J. , Isaac Maria , Bain Lisa , Carrillo Maria C. 
Published: November 2014

AbstractSeveral lines of evidence from Alzheimer's disease (AD) research continue to support the notion that the biological changes associated with AD are occurring possibly several decades before an individual will experience the cognitive and functional changes associated with the disease. The National Institute on Aging—Alzheimer's Association revised criteria for AD provided a framework for this new thinking. As a result of this growing understanding, several research efforts have launched or will be launching large secondary prevention trials in AD. These and other efforts have clearly demonstrated a need for better measures of cognitive and functional change in people with the earliest changes associated with AD. Recent draft guidance from the US Food and Drug Administration further elevated the importance of cognitive and functional assessments in early stage clinical trials by proposing that even in the pre‐symptomatic stages of the disease, approval will be contingent on demonstrating clinical meaningfulness. The Alzheimer's Association's Research Roundtable addressed these issues at its fall meeting October 28–29, 2013, in Washington, D.C. The focus of the discussion included the need for improved cognitive and functional outcome measures for clinical of participants with preclinical AD and those diagnosed with Mild Cognitive Impairment due to AD.
Independent comparison of CogState computerized testing and a standard cognitive battery with neuroimaging
Authors: Mielke Michelle M. , Weigand Stephen D. , Wiste Heather J. , Vemuri Prashanthi , Machulda Mary M. , Knopman Davis S. , Lowe Val , Roberts Rosebud O. , Kantarci Kejal , Rocca Walter A. , Jack Clifford R. , Petersen Ronald C. 
Published: November 2014

AbstractBackgroundInexpensive, non‐invasive tools for assessing Alzheimer‐type pathophysiologies are needed. Computerized cognitive assessments are prime candidates.MethodsCognitively normal participants, aged 51–71, with magnetic resonance imaging, fluorodeoxyglucose‐positron emission tomography (FDG‐PET), amyloid PET, CogState computerized cognitive assessment, and standard neuropsychological tests were included. We first examined the association between the CogState battery and neuroimaging measures. We then compared that association to the one between standard neuropsychological z‐scores and neuroimaging.ResultsSlower reaction times for CogState Identification and One Back, and lower memory and attention z‐scores, were associated (P < .05) with FDG‐PET hypometabolism. Slower time on the Groton Maze Learning Task and worse One Card Learning accuracy were associated (P < .05) with smaller hippocampal volumes. There were no associations with amyloid PET. Associations of CogState and neuropsychological Z‐scores with neuroimaging were small and of a similar magnitude.ConclusionsCogState subtests were cross‐sectionally comparable to standard neuropsychological tests in their relatively weak associations with neurodegeneration imaging markers.
Compact parylene‐c‐coated flexible antenna for WLAN and upper‐band UWB applications
Authors: Qiu Yijie , Jung Yei Hwan , Lee Subin , Shih Ting‐Yen , Lee Juhwan , Xu Yue Hang , Xu Ruimin , Lin Weigan , Behdad Nader , Ma Zhenqiang 
Published: November 2014

A compact broadband flexible antenna is proposed for applications in wireless local area network (WLAN) and upper ultra‐wideband (UWB) systems, which can operate in the bandwidths of 2.4–2.484 GHz and 3.5–10.6 GHz with a reflection coefficient of <−10 dB. The presented antenna coated with bio‐compatible ultra‐thin parylene‐c is fabricated on a thin polyimide substrate with a thickness of 127 μm. The characteristics of the proposed antenna are measured under bending and flat conditions. The measured results showed that the antenna is suitable for integration with flexible electronic devices.
A prompt radio transient associated with a gamma-ray superflare from the young M dwarf binary DG CVn
Authors: Fender R. P. , Anderson G. E. , Osten R. , Staley T. , Rumsey C. , Grainge K. , Saunders R. D. E. 
Published: November 2014

Abstract
On 2014 April 23, the Swift satellite detected a gamma-ray superflare from the nearby star system DG CVn. This system comprises an M-dwarf binary with extreme properties: it is very young and at least one of the components is a very rapid rotator. The gamma-ray superflare is one of only a handful detected by Swift in a decade. As part of our AMI-LA Rapid Response Mode, ALARRM, we automatically slewed to this target, were taking data at 15 GHz within 6 min of the burst, and detected a bright (∼100 mJy) radio flare. This is the earliest detection of bright, prompt, radio emission from a high-energy transient ever made with a radio telescope, and is possibly the most luminous incoherent radio flare ever observed from a red dwarf star. An additional bright radio flare, peaking at around 90 mJy, occurred around one day later, and there may have been further events between 0.1–1 d when we had no radio coverage. The source subsequently returned to a quiescent level of 2–3 mJy on a time-scale of about 4 d. Although radio emission is known to be associated with active stars, this is the first detection of large radio flares associated with a gamma-ray superflare, and demonstrates both feasibility and scientific importance of rapid response modes on radio telescopes.
Making decision‐making research matter: some issues and remedies
Authors: Nutt Paul C. 
Published: November 2014

PurposeThe purpose of this paper is to provide an appraisal of decision‐making research noting key contributions, issues posed by past work and suggestions for future work that address the issues.Design/methodology/approachThe appraisal stems from a meta analysis of decision‐making research efforts. Summative analyses of decision‐making research, found in key papers and books published in the past two decades, were examined integrating the conclusions to offer an assessment of the field.FindingsThe key findings were “what” and “how” questions that need be addressed. The what questions identify some of the dilemmas that must be confronted before decision making can progress. The how questions consider some of the difficulties inherent in doing the recommended research. Suggestions to overcome these difficulties are offered.Originality/valueThe paper's key contribution stems from pinpointing the failures of past efforts and steps identified to overcome these failings, which should be of interest to researchers.
Interview with Alex Pratt, author of Austerity Business
Authors: by Juliet Norton Interview 
Published: November 2014

PurposeThe purpose of this paper is to provide an interview with Alex Pratt, an award winning entrepreneur and one of the UK's leading business figures. He started trading bankrupt stock at the age of 16, and was quickly spotted as a national rising business star. Today, Alex is Director of Serious Brands. He has worked with several governments as an advisor on business, competitiveness and innovationDesign/methodology/approachThis briefing is prepared by an independent interviewer.FindingsAfter decades of growth, business leaders are now facing unfamiliar territory, the biggest cuts in spending since the Great Depression and a more uncertain future. In addition, to tackling the economic challenges, entrepreneurs need to keep their eyes open for emerging opportunities like those related to the transition to a greener, lower carbon economy. In his new book Austerity Business: 39 Tips for Doing More with Less. Alex offers help and inspiration to businesses in dealing with the new “Age of Austerity”.Practical implicationsProvides strategic insights and practical thinking that have influenced some of the world's leading organizations.Social implicationsProvides strategic insights and practical thinking that can have a broader social impact.Originality/valueAlex book offers advice on how companies can thrive during a period of austerity.
Country risk and valuation of US‐listed foreign IPOs
Authors: Wu Congsheng 
Published: November 2014

PurposeMany foreign firms have made their initial public offering (IPO) debuts in the USA, without first being listed in their home market. The purpose of this paper is to investigate the association of a wide range of country risk measures with the valuation of foreign IPOs.Design/methodology/approachBased on the law and finance literature, it is hypothesized that IPO firms domiciled in countries with higher country risk are worth less, other things equal. This hypothesis is tested with a sample of international companies making their IPO debuts in the USA between 1986 and 2002.FindingsIt is found that several commonly used country‐level variables explain the observed IPO valuation differences across countries. In particular, the index of economic freedom, developed by the Heritage Foundation, and the Transparency International's corruption index have a significant impact on post‐offer IPO valuations. Specifically, IPO firms hailing from countries with more economic freedom and less corruption are associated with higher valuation in the aftermarket.Originality/valueThe paper investigates whether some commonly‐used country risk measures affect the valuation of newly US‐listed foreign firms.
Public Library Association Biennial Conference, March 2012
Authors: Kesselman Martin 
Published: November 2014

PurposeThe purpose of this paper is to review the 2012 PLA Conference.Design/methodology/approachThis paper is a conference report from the Public Library Association (PLA) Biennial Conference held in March 2012.FindingsVarious reports from the conference.Originality/valueThis conference report has editorial value to those interested in attending the PLA conference and interest for librarians and information professionals.
Models of teamwork: ideal or not? A critical study of theoretical team models
Authors: Berlin Johan M. , Carlström Eric D. , Sandberg Håkan S. 
Published: November 2014

PurposeThere is a tendency in team research to employ concepts of stepwise models, reaching from the primitive to the excellent, to suggest that a higher level of evolution is better than the basic and simple. This tendency includes typologies of teams. This article aims to question the relevance of this view.Design/methodology/approachData were collected in three steps. In the first step, articles and books analyzing teams and teamwork from stepwise analytical models were collected. In the second step the collected data were classified into different themes. Each stepwise model was classified into one essential denomination. This classification resulted in eight themes. In the third step each theme was analyzed, which led to the fusion of some of the themes.FindingsThe conclusion is that a synchronous, complementary or mature team is not necessarily optimal. Contrary to this, a differentiated, sequential or multi team approach can be optimal for some purposes. Team research needs to establish a more open, inductive and critical attitude than at present.Originality/valueThe paper highlights the need to observe and use team theories in a balanced and critical way.
“A funny thing happened on the way to the hypogeum”
Authors: Garvey Darren 
Published: November 2014

PurposeThe purpose of this paper is to provide an account of the author's negotiation of a methodological and personal crisis that emerged in the course of his PhD research. It provides a description of the research project and how, in its implementation, questions emerged for the author regarding the likely “indigenous credibility” of the work, and the repercussions of this for him as an indigenous researcher.Design/methodology/approachThe author provides a narrative account of the events and responses, identifying critical issues, courses of action and subsequent outcomes. Opportunity is also provided for the reader to consider their own response to the issues identified.FindingsThe author discovered that the initial misgivings regarding the research project were misguided following a broader reading of the literature regarding Indigenous Standpoint Theory and Causal Layered Analysis. Indeed, as well as allaying the initial anxieties, a number of aspirational congruities between the approaches became evident which, in the opinion of the author, will lead to a differently rendered layering of the arena of indigenous mental health. The author also discovered that a source of his initial misgivings were related to his own essentialised constructions of what constitutes credible indigenous research.Research limitations/implicationsThe paper has implications for those indigenous researchers who may be grappling with methodological issues related to their research, particularly those considerations regarding Indigenous Standpoint and other nominally indigenous theories/methodologies.Originality/valueThe paper presents a novel attempt to compare and contrast methodologies specifically identified as indigenous, with those that could be utilised as complementary to them. Such attempts at collaboration serve to challenge essentialised expectations about what can constitute meaningful research by, and for indigenous Australian people.
Think relationships: caring for someone with dementia
Authors: Pointon Barbara 
Published: November 2014

PurposeThis paper aims to offer a family carer's personal account of the importance of relationships between the person with dementia, their carer, family, friends, health and social care professionals, and the workforce who offer care, from pre‐diagnosis through 16 years of decline to death.Design/methodology/approachA personal account from the point of view of a former carer of a person with dementia.FindingsThe thread throughout the narrative of this paper is the necessity for everyone who comes into contact with the person with dementia to develop a much greater understanding of what it is like to live with the condition and as a result, how more enlightened care and support can be offered. Central to this is access to expert advice concerning dementia care and support in order to achieve the main goal of protecting and maintaining relationships.Originality/valueThe author draws on personal experiences and reflects on the lessons learned during the time as her husband's carer and information she wished she had possessed earlier.
Living with dementia in a care home: capturing the experiences of residents
Authors: Milne Alisoun 
Published: November 2014

PurposeThe purpose of this paper is to consider the experiences and perspectives of residents with dementia living in a care home.Design/methodology/approachThe paper reviews current sources of evidence about “the care home experience”, including material drawn from: research instruments, interviews, observational methods and phenomenological research which aims to capture the lived experiences of residents.FindingsResearch that is attempting to capture the lived experiences of residents further adds to the understanding of quality of life (QoL) and quality of care. Specifically, residents prioritise non‐disease‐related domains of QoL, which is somewhat different than those identified by relatives, care home staff and “objective” measures.Originality/valueNot only is it evident that residents are able to describe aspects of their situation but they appear to retain a sense of self and identity. There is a distinctive need for assessment of QoL amongst residents with dementia that places their subjective view of this concept at its core.
Metals evaluation in coastal wetlands receiving treated wastewater
Authors: Jin Guang , Englande A.J. , Hu Chih‐Yang 
Published: November 2014

PurposeThe purpose of this paper is to describe the investigation of distribution of metals in water and sediment samples of Poydras‐Verret wetland, an area that has received approximately 40 years input of secondarily treated municipal effluent.Design/methodology/approachWater and sediment samples were analyzed for metals for a period of 18 months. These metals were also monitored for the secondarily treated effluent, and at a reference/control wetland that does not receive wastewater. Analysis of variance (ANOVA) and Student Newman‐Keuls post‐hoc ANOVA analysis were conducted to evaluate the pattern of metal distribution within the Poygras‐Verret wetland and compare results to the reference wetland. Heavy metal criteria established by United States Environmental Protection Agency (USEPA) and State of Louisiana were also used to assess the potential chronic and acute health impacts of heavy metals in the Poydras‐Verret wetland.FindingsConcentrations of metals of the Poydras‐Verret wetland water are not different from those found in the reference wetland water, suggesting no observed accumulation of these metals within the receiving wetland water. All metals are below the acute criteria.Originality/valueHistorical data regarding metal accumulation in wetlands in the published literature is limited. This paper provides supporting evidence that using wetlands to assimilate wastewater could be a long‐term, practical solution with the side benefits including wetland restorations and protection from wave erosion and storm surge.
A review of energy efficiency policy and measures for industries in Latvia
Authors: Ozoliņa Līga , Rosˇā Marika 
Published: November 2014

PurposeThe purpose of this paper is to review and evaluate energy use and performance, as well as existing energy efficiency policy and measures in the Latvian industrial sector, in order to highlight possible scenarios for energy efficiency improvements in the future.Design/methodology/approachThe paper takes the form of a literature review and data analysis.FindingsIt is concluded that the existing energy efficiency measures for the industrial sector in Latvia do not work effectively. Also, it is expected that the planned measures for energy efficiency improvements for the industrial sector will not reach the defined energy saving targets in the framework of the Latvian NEEAP. Therefore, it is necessary to develop a common strategy on energy efficiency in the industrial sector in Latvia. This should be accomplished by reviewing the existing literature and data, as well as drawing up new, well‐designed energy efficiency measures.Practical implicationsThe results of this study can be applied and used in the development of energy efficiency policy for the industrial sector in Latvia. The paper also points out the main weak points of existing policy measures that can be improved in order to meet the energy saving target for the Latvian industrial sector.Originality/valueIn this paper, the Latvian industrial sector's energy efficiency policy and related measures have been organized and evaluated for the first time. Also, the importance of energy efficiency improvements in the industrial sector has been highlighted. This is evident from the fact that, currently, almost no energy efficiency measure for the industrial sector in Latvia works sufficiently.
Optimizing the weld bead characteristics of super austenitic stainless steel (904L) through grey‐based Taguchi method
Authors: Sathiya P. , Aravindan S. , Jeyapaul R. , Ajith P.M. , Noorul Haq A. 
Published: November 2014

PurposeThe purpose of this paper is to optimize the gas metal arc welding (GMAW) process input parameters simultaneously considering the multiple output variables (bead width (BW), bead height (BH) and depth of penetration (DP)).Design/methodology/approachGrey‐based Taguchi approach was used for designing the experiment, L27 orthogonal array was used which composed of three levels and 27 rows, which means that 27 experiments were carried out. Design of experiments was selected based on a four welding parameters with three levels each. The selected welding parameters for this paper are gas flow rate, voltage, travel speed and wire feed rate. The bead‐on‐plate welding trials are carried out on AISI 904L super austenitic stainless steel (SASS) sheets and evaluate the shape of the fusion zone depends upon a number of input parameters.FindingsBead‐on‐plate welding of 904L SASS sheet is successfully performed (without any cracks and discontinuity) by GMAW process and the bead profiles are measured. The predicted bead profiles have the better DP and lower BH and BW. It is found that the optimized setting values are improving the response values by 10 per cent.Originality/valueThe optimal welding conditions are identified in order to increase the productivity and minimize the total operating cost. The process input parameters effect is determined under the optimal welding combinations.