bluuebunny/crossref_metadata_2025_split huggingface dataset:
Viscosity iterative algorithm for variational inequality problems and fixed point problems in a real q-uniformly smooth Banach space
Authors: Cai Gang 
Published: May 2015

AbstractThe purpose of this paper is to study a viscosity iterative algorithm for finding a common element of the set of solutions of a general variational inequality problem for two inverse strongly accretive operators and the set of fixed points of a δ-strict pseudocontraction in a real q-uniformly smooth Banach space. Some strong convergence theorems are obtained under appropriate conditions. As an application, we prove some strong convergence theorems for fixed point problems and variational inequality problems or equilibrium problems in Hilbert spaces. These results improve and extend the corresponding results announced by many others.
The scientific information provided through patents and its limited use in scientific research at universities
Authors: Pereira Cristiano Gonçalves , da Silva Rodrigo Ribeiro , Porto Geciane Silveira 
Published: May 2015

AbstractThis study aimed to evaluate the importance of protecting the knowledge generated by the university through patents, and assess the use of information available in patent database as a source of scientific and technological information. To this end, the doctoral theses defended in 2010 to 2012 year at the Basic and Applied Immunology FMRP/USP Post Graduation Program, were evaluated considering patent applications by the authors involved, as well as by other national/international unrelated research groups. The data showed that only 8% of the thesis (two) had its results added to a patent filing. Moreover, no other student was found to held a patent resulting in other researches, and also, a few supervisors are researchers who held authored/co-authored of patent filling. When we assessed if theses’ results and applications had been patented by other groups not related to the thesis group, it was noted that there was no record of patent filling in 46% of theses, and in this group, it was included researches with strong potential for patentability, but the authors didn’t applied for a patent deposit. The remaining 54%, representing 14 theses, had part or the whole knowledge disclosed in patents documents, five of these were specific about the topic and the results of the thesis, presuming that there was a likely duplicity in the development of the research. We can conclude that the study was once repeated since no searching for information in patents databases were properly performed as reference source in the development phase of their research projects. The results of this research indicates that the use of patents database, as a source of technological information by the universities is an urgent requirement, since represent a rich scientific information bank that should be aggregated with the information available in papers to conduct innovative research.
Definitive and Adjuvant Radiotherapy in Locally Advanced Non–Small-Cell Lung Cancer: American Society of Clinical Oncology Clinical Practice Guideline Endorsement of the American Society for Radiation Oncology Evidence-Based Clinical Practice Guideline
Authors: Bezjak Andrea , Temin Sarah , Franklin Gregg , Giaccone Giuseppe , Govindan Ramaswamy , Johnson Melissa L. , Rimner Andreas , Schneider Bryan J. , Strawn John , Azzoli Christopher G. 
Published: May 2015

Purpose The American Society for Radiation Oncology (ASTRO) produced an evidence-based guideline on external-beam radiotherapy for patients with locally advanced non–small-cell lung cancer (NSCLC). Because of its relevance to the American Society of Clinical Oncology (ASCO) membership, ASCO endorsed the guideline after applying a set of procedures and a policy that are used to critically examine and endorse guidelines developed by other guideline development organizations. Methods The ASTRO guideline was reviewed by ASCO content experts for clinical accuracy and by ASCO methodologists for developmental rigor. On favorable review, an ASCO expert panel was convened and endorsed the guideline. The ASCO guideline approval body, the Clinical Practice Guideline Committee, approved the final endorsement. Results The recommendations from the ASTRO guideline, published in Practical Radiation Oncology, are clear, thorough, and based on the most relevant scientific evidence. The ASCO Endorsement Panel endorsed the guideline and added qualifying statements. Recommendations For curative-intent treatment of locally advanced NSCLC, concurrent chemoradiotherapy improves local control and overall survival compared with sequential chemotherapy followed by radiation. The standard dose-fractionation of radiation is 60 Gy given in 2-Gy once-daily fractions over 6 weeks. There is no role for the routine use of induction therapy before chemoradiotherapy. Current data fail to support a clear role for consolidation therapy after chemoradiotherapy; however, consolidation therapy remains an option for patients who did not receive full systemic chemotherapy doses during radiotherapy. Important questions remain about the ideal concurrent chemotherapy regimen and optimal management of patients with resectable stage III disease.
Structural Insights Into Thyroid Hormone Transport Mechanisms of the L-Type Amino Acid Transporter 2
Authors: Hinz Katrin M. , Meyer Katja , Kinne Anita , Schülein Ralf , Köhrle Josef , Krause Gerd 
Published: May 2015

Abstract
Thyroid hormones (THs) are transported across cell membranes by different transmembrane transporter proteins. In previous studies, we showed marked 3,3′-diiodothyronine (3,3′-T2) but moderate T3 uptake by the L-type amino acid transporter 2 (Lat2). We have now studied the structure-function relationships of this transporter and TH-like molecules. Our Lat2 homology model is based on 2 crystal structures of the homologous 12-transmembrane helix transporters arginine/agmatine antiporter and amino acid/polyamine/organocation transporter. Model-driven mutagenesis of residues lining an extracellular recognition site and a TH-traversing channel identified 9 sensitive residues. Using Xenopus laevis oocytes as expression system, we found that side chain shortening (N51S, N133S, N248S, and Y130A) expanded the channel and increased 3,3′-T2 transport. Side chain enlargements (T140F, Y130R, and I137M) decreased 3,3′-T2 uptake, indicating channel obstructions. The opposite results with mutations maintaining (F242W) or impairing (F242V) uptake suggest that F242 may have a gating function. Competitive inhibition studies of 14 TH-like compounds revealed that recognition by Lat2 requires amino and carboxylic acid groups. The size of the adjacent hydrophobic group is restricted. Bulky substituents in positions 3 and 5 of the tyrosine ring are allowed. The phenolic ring may be enlarged, provided that the whole molecule is flexible enough to fit into the distinctly shaped TH-traversing channel of Lat2. Taken together, the next Lat2 features were identified 1) TH recognition site; 2) TH-traversing channel in the center of Lat2; and 3) switch site that potentially facilitates intracellular substrate release. Together with identified substrate features, these data help to elucidate the molecular mechanisms and role of Lat2 in T2 transport.
Projective geometry in characteristic one and the epicyclic category
Authors: Connes Alain , Consani Caterina 
Published: May 2015

AbstractWe show that the cyclic and epicyclic categories which play a key role in the encoding of cyclic homology and the lambda operations, are obtained from projective geometry in characteristic one over the infinite semifield of max-plus integers ℤmax. Finite-dimensional vector spaces are replaced by modules defined by restriction of scalars from the one-dimensional free module, using the Frobenius endomorphisms of ℤmax. The associated projective spaces are finite and provide a mathematically consistent interpretation of Tits's original idea of a geometry over the absolute point. The self-duality of the cyclic category and the cyclic descent number of permutations both acquire a geometric meaning.
The M-set of λ exp(z)/z has infinite area
Authors: Zhan Guoping , Liao Liangwen 
Published: May 2015

AbstractIt is known that the Fatou set of the map exp(z)/z defined on the punctured plane ℂ* is empty. We consider the M-set of λ exp(z)/z consisting of all parameters λ for which the Fatou set of λexp(z)/z is empty. We prove that the M-set of λexp(z)/z has infinite area. In particular, the Hausdorff dimension of the M-set is 2. We also discuss the area of complement of the M-set.
Early vascular unclamping reduces warm ischaemia time in robot-assisted laparoscopic partial nephrectomy
Authors: Lah Kevin , Desai Devang , Chabert Charles , Gericke Christian , Gianduzzo Troy 
Published: May 2015

Introduction: The aim of this study was to assess the outcomes of early vascular release in robot-assisted laparoscopic partial nephrectomy (RAPN) to reduce warm ischaemia time (WIT) and minimise renal dysfunction. RAPN is increasingly utilised in the management of small renal masses. To this end it is imperative that WIT is kept to a minimum to maintain renal function.Methods: RAPN was performed via a four-arm robotic transperitoneal approach. The renal artery and vein were individually clamped with robotic vascular bulldog clamps to allow cold scissor excision of the tumour. The cut surface was then sutured with one or two running 3-0 V-LocTM sutures, following which the vascular clamps were released. Specific bleeding vessels were then selectively oversewn and the collecting system repaired. Renorrhaphy was then completed using a running horizontal mattress 0-0 V-LocTM suture.Results: A total of 16 patients underwent RAPN with a median WIT of 15 minutes (range: 8-25), operative time 230 minutes (range: 180-280) and blood loss of 100 mL (range: 50-1000). There were no transfusions, secondary haemorrhages or urine leaks. There was one focal positive margin in a central 5.5 cm pT3a renal cell carcinomas (RCC). Long-term estimated glomerular filtration rate (eGFR) was not significantly different to pre-operative values.Conclusion: In this patient series, early vascular release effectively minimised WIT and maintained renal function without compromising perioperative safety.
Biocompatibility of single-walled carbon nanotube composites for bone regeneration
Authors: Gupta A. , Liberati T. A. , Verhulst S. J. , Main B. J. , Roberts M. H. , Potty A. G. R. , Pylawka T. K. , El-Amin III S. F. 
Published: May 2015

Objectives The purpose of this study was to evaluate in vivo biocompatibility of novel single-walled carbon nanotubes (SWCNT)/poly(lactic-co-glycolic acid) (PLAGA) composites for applications in bone and tissue regeneration. Methods A total of 60 Sprague-Dawley rats (125 g to 149 g) were implanted subcutaneously with SWCNT/PLAGA composites (10 mg SWCNT and 1gm PLAGA 12 mm diameter two-dimensional disks), and at two, four, eight and 12 weeks post-implantation were compared with control (Sham) and PLAGA (five rats per group/point in time). Rats were observed for signs of morbidity, overt toxicity, weight gain and food consumption, while haematology, urinalysis and histopathology were completed when the animals were killed. Results No mortality and clinical signs were observed. All groups showed consistent weight gain, and the rate of gain for each group was similar. All groups exhibited a similar pattern for food consumption. No difference in urinalysis, haematology, and absolute and relative organ weight was observed. A mild to moderate increase in the summary toxicity (sumtox) score was observed for PLAGA and SWCNT/PLAGA implanted animals, whereas the control animals did not show any response. Both PLAGA and SWCNT/PLAGA showed a significantly higher sumtox score compared with the control group at all time intervals. However, there was no significant difference between PLAGA and SWCNT/PLAGA groups. Conclusions Our results demonstrate that SWCNT/PLAGA composites exhibited in vivo biocompatibility similar to the Food and Drug Administration approved biocompatible polymer, PLAGA, over a period of 12 weeks. These results showed potential of SWCNT/PLAGA composites for bone regeneration as the low percentage of SWCNT did not elicit a localised or general overt toxicity. Following the 12-week exposure, the material was considered to have an acceptable biocompatibility to warrant further long-term and more invasive in vivo studies. Cite this article: Bone Joint Res 2015;4:70–7
Assessment Of Renal Function Using Canine Cystatin-C Levels In Canine Babesiosis And Ehrlichiosis
Authors: Didem PEKMEZCI , Kerem URAL , Nuran AYSUL , Murat GUZEL , Gulay CIFTCI 
Published: May 2015

Abstract
The purpose of the present study was to evaluate serum canine Cystatin-C (Cys-C) concentration for the prediction of renal function (RF) in dogs naturally infected with Babesia canis vogeli and Ehrlichia canis. A total of 46 dogs were enrolled into three groups. Group B included 16 dogs naturally infected with B. c. vogeli, group E 10 dogs naturally infected with E. canis [dogs diagnosed as canine monocytic ehrlichiosis (CME)], and group H involved 20 healthy controls (negative for B. c. vogeli and E. canis). Solely dogs presenting uncomplicated babesiosis caused by B. c. vogeli were enrolled. Serum urea and serum creatinine (Cre) levels with serum Urea:Cre ratios were analyzed. Canine serum Cys-C was determined with a species-specific commercially available and validated ELISA assay as a reference. Mean serum Cys-C levels were 5.28 mg/L, 3.02 mg/L, and 2.30 mg/L for groups B, E and H, respectively. RF in uncomplicated CB caused by B. c. vogeli seems to be affected based on serum Cys-C concentrations. To the author's knowledge, this is the first study reporting that mean serum canine Cys-C levels in dogs with CME demonstrated no elevation. Serum canine Cys-C as a novel RF marker could be used for early detection of renal injury in both babesiosis and CME.
Survey Of Infectious Agents Associated With Porcine Respiratory Disease Complex (PRDC) In Serbian Swine Herds Using Polymerase Chain Reaction (PCR) Detection
Authors: Božidar SAVIĆ , Oliver RADANOVIĆ , Dubravka JOVIČIĆ , Ksenija NEŠIĆ , Snežana IVANOVIĆ , Ognjen STEVANČEVIĆ , Đorđe CVETOJEVIĆ , Dragan KASAGIĆ 
Published: May 2015

Abstract
A retrospective study on 235 natural cases of Porcine Respiratory Disease Complex in order to determine the etiological agents, their prevalence and interrelationships was performed in Serbia. Lung tissue samples were analyzed by Polymerase Chain Reaction for the presence of Porcine circovirus type 2, Porcine reproductive and respiratory virus, Swine influenza virus, Mycoplasma hyopneumoniae, Pasteurella multocida, Actinobacillus pleuropneumoniae, Haemophilus parasuis, Streptococcus suis and Arcanobacterium pyogenes. A total of 49 different combinations of viral and bacterial pathogens were found. Five different viral and viral/Mhp co-infections were detected. Monobacterial infections were found in 150 cases and polybacterial infection was detected in 85 samples. PCV2 was the main virus detected, and Pm was the most aggressive secondary pathogen detected in PRDC. The reason for PRDC being so prevalent among Serbian pigs is most likely due to the large number of risk factors in the conventional farrow-to-finish system, compared to multi-site production systems. Therefore, measures aimed at a better control of respiratory viruses, particularly Porcine circovirus type 2 and Porcine reproductive and respiratory virus, as well as Mycoplasma hyopneumoniae infections, and adoption of rational decisions on respiratory bacterial pathogens specific therapeutic and preventive strategies at herd level, simultaneously with significant improvements on farm management should reduce the occurrence of PRDC.
Morphological, Biochemical And Hematological Characterization Of Endangered Balkan Donkey Breed
Authors: Ljubodrag STANIŠIĆ , Vladimir DIMITRIJEVIĆ , Predrag SIMEUNOVIĆ , Nada LAKIĆ , Ivica RADOVIĆ , Ante IVANKOVIĆ , Jevrosima STEVANOVIĆ , Zoran STANIMIROVIĆ 
Published: May 2015

Abstract
The aim of the study was to establish morphometric, biochemical and hematological values for the endangered Balkan donkey breed (Serbia) and to explore the possible age dependence of the parameters tested. Inter-breed similarity of morphometric parameters was assessed by comparing the data obtained for the Balkan donkey with morphometric measurements of several previously characterized domestic donkey breeds. The study population included 74 donkeys, divided in two age groups (group A ≤ 3 years; group B > 3 years). In total, 18 morphometric, 13 hematological and 14 biochemical parameters were assessed. Significant morphometric differences (p<0.05) in body length, head length, chest circumference and body weight were found between the two age groups. Significant differences in morphological parameters were revealed among the Balkan donkey and other donkey breeds (Catalonian, Croatian and Albanian), but results of cluster analysis demonstrated the smallest distance between the Balkan donkey and Albanian donkeys. The results of morphometric analyses showed consistency of the obtained values within the breed, and diversity as compared to other donkey breeds, and, thus, could be taken as referent for the Balkan donkey. Hematological and biochemical profiles obtained for the Balkan donkey were consistent with previous reports and within the recommended reference ranges. White blood cell, mid cell and granulocyte counts, showed significantly higher (p<0.05) values in donkeys under 3 years of age, while the only biochemical parameter affected by age was alkaline phosphatase. The information gained through characterization of the Balkan donkey breed provides a basis for conservation and development of the breed standard.
Brain Metastasis In A Case Of Canine Transmissible Venereal Tumor After A Supposed Successful Treatment With Vincristine Sulfate
Authors: Pedro PINCZOWSKI , Marina GIMENO , Carmen ACEÑA , Ainara VILLEGAS , Alba de MARTINO , Lluís LUJÁN 
Published: May 2015

Abstract
A ten year old mongrel bitch was diagnosed with a primary vulvar transmissible venereal tumor (TVT) causing subcutaneous, mammary and splenic metastasis and it was successfully treated with vincristine. Four months later the animal presented neurological disturbances, brain metastases were suspected and the animal was euthanized. A TVT metastatic mass was found in the brain and confirmed with immunohistochemical results, being positive for vimentin and lysozyme and negative for S-100, CD3 and cytokeratin. TVT metastases in the brain are a rare event and cannot be treated with usual chemotherapy as vincristine does not cross the blood-brain barrier, thus allowing the re-emergence of the tumor after a period of time.
Nasal Transmissible Venereal Tumor In A Jack Russel Terrier Bitch
Authors: Adrian FEGHIU , Dan CRÎNGANU , Florin DUMITRESCU , Manuela PASCAL , Florina VASILESCU , Manuella MILITARU 
Published: May 2015

Abstract
A two-year old Jack Russell Terrier female with left-sided epistaxis was brought to the Clinic of the Bucharest Faculty of Veterinary Medicine. Endoscopy of the left nasal cavity revealed a cauliflower-like mass. Cytological and histopathological features were specific to canine transmissible venereal tumour (CTVT). Tumor tissue showed positive immunoreactivity to anti-vimentin monoclonal antibody (90%) and Ki67 (35%) and samples were negative for anti-cytokeratin monoclonal antibody. Chemotherapy with vincristine sulphate at a dose of 0.025 mg/kg i.v./week for 6 administrations was successful. This paper presents a primary form of nasal CTVT in a Jack Russell Terrier female.
Influence of Friction Stir Welding on Corrosion Properties of Aw-7020M Alloy in Sea Water
Authors: Dudzik K. , Jurczak W. 
Published: May 2015

Abstract
Friction Stir Welding (FSW), provides an alternative to MIG and TIG welding methods for joining aluminium alloys. The article presents the results of electrochemical corrosion resistance test of alloy AW- 7020M and its joints welded by FSW. The study was performed using the method of electrochemical impedance spectroscopy (EIS). Impedance spectroscopy studies showed that both, the FSW welded joint and base material AW-7020M has a good resistance to electrochemical corrosion in sea water environment, wherein the welded joint has a higher susceptibility to this type of corrosion. Research has indicated the desirability of applying the FSW method for joining AW-7020M alloy in shipbuilding industry.
Clay Minerals – Mineralogy and Phenomenon of Clay Swelling in Oil & Gas Industry
Authors: Karpiński B. , Szkodo M. 
Published: May 2015

Abstract
Among the minerals found in the earth's crust, clay minerals are of the widest interest. Due to the specific properties such as plasticity, absorbing and catalytic properties clay minerals are used in many industries (oil & gas, chemistry, pharmacy, refractory technology, ceramics etc.). In drilling, a phenomenon of swelling clays is frequently observed. It has an important impact on the cementing quality. During the last few decades clays have been the subject of research on a scale unprecedented in the history of mineralogy. This paper presents review literature on mineralogy of clay minerals and phenomenon of swelling in oil and gas industry. Unique ion exchange properties and clay swelling mechanisms are also considered.
Air pollution in landfill of wastes other than hazardous or inert / Zanieczyszczenia powietrza na składowiskach odpadów innych niż niebezpieczne i obojętne
Authors: Miaśkiewicz-Pęska Ewa , Szyłak-Szydłowski Mirosław 
Published: May 2015

Abstract
Microbiological and chemical analysis of air was carried out on the area of landfill of wastes other than inert or hazardous. The landfill covers 20 ha and 40 000 Mg of wastes is deposited annually. Municipal waste is not segregated at the landfill. The research was conducted in April, May and November 2012. Number of the psychrophilic and mesophilic bacteria and fungi was estimated by a culture-based method. Quantitative determination of sulfur compounds and meteorological and olfactrometric examinations were also carried out. Chemical analysis was conducted with a Photovac Voyager portable gas chromatograph. Air samples were collected at 5 points. The largest group of microbes were psychrophilic bacteria, especially in summer. The highest concentration of hydrogen sulfide and other odorants was found at leachate tank and landfill body. According to the Polish Standard for the assessment of atmospheric air pollution the air in the area of the landfill is classified as not contaminated and sporadically moderately contaminated. In spring and summer the number of microscopic fungi was increased also in control samples.