bluuebunny/crossref_metadata_2025_split huggingface dataset:
Windowing and random weighting‐based adaptive unscented Kalman filter
Authors: Gao Shesheng , Hu Gaoge , Zhong Yongmin 
Published: January 2014

SummaryThe conventional unscented Kalman filter (UKF) requires prior knowledge on system noise statistics. If the statistical characteristics of system noise are not known exactly, the filtering solution will be biased or even divergent. This paper presents an adaptive UKF by combining the windowing and random weighting concepts to address this problem. It extends the windowing concept from the linear Kalman filter to the nonlinear UKF for estimation of system noise statistics. Subsequently, the random weighting concept is adopted to refine the obtained windowing estimation by adjusting random weights of each window. The proposed adaptive UKF overcomes the limitation of the conventional UKF by online estimating and adjusting system noise statistics. Experimental results and comparison analysis demonstrate that the proposed adaptive UKF outperforms the conventional UKF and adaptive robust UKF under the condition without precise knowledge on system noise statistics.Copyright © 2014 John Wiley & Sons, Ltd.
Examining occupational health and safety disparities using national data: A cause for continuing concern
Authors: Steege Andrea L. , Baron Sherry L. , Marsh Suzanne M. , Menéndez Cammie Chaumont , Myers John R. 
Published: January 2014

BackgroundOccupational status, a core component of socioeconomic status, plays a critical role in the well‐being of U.S. workers. Identifying work‐related disparities can help target prevention efforts.MethodsBureau of Labor Statistics workplace data were used to characterize high‐risk occupations and examine relationships between demographic and work‐related variables and fatality.ResultsEmployment in high‐injury/illness occupations was independently associated with being male, Black, ≤high school degree, foreign‐birth, and low‐wages. Adjusted fatal occupational injury rate ratios for 2005–2009 were elevated for males, older workers, and several industries and occupations. Agriculture/forestry/fishing and mining industries and transportation and materials moving occupations had the highest rate ratios. Homicide rate ratios were elevated for Black, American Indian/Alaska Native/Asian/Pacific Islanders, and foreign‐born workers.ConclusionsThese findings highlight the importance of understanding patterns of disparities of workplace injuries, illnesses and fatalities. Results can improve intervention efforts by developing programs that better meet the needs of the increasingly diverse U.S. workforce. Am. J. Ind. Med. 57:527–538, 2014. Published 2014. This article is a U.S. Government work and is in the public domain in the USA.
Quantitative Photoswitching in Bis(dithiazole)ethene Enables Modulation of Light for Encoding Optical Signals
Authors: Wu Yue , Xie Yongshu , Zhang Qiong , Tian He , Zhu Weihong , Li Alexander D. Q. 
Published: January 2014

AbstractUsing one ray of light to encode another ray of light is highly desirable because information in optical format can be directly transferred from one beam to another without converting back to the electronic format. One key medium to accomplish such an amazing task is photoswitchable molecules. Using bis(dithiazole)ethene that can be photoswitched between its ring‐open and ring‐closed states quantitatively with excellent fatigue resistance and high thermal stability, it is shown that quantitative photoreversibility allowed the photoswitching light to control other light travelling through the photoswitchable medium, a phenomenon of transferring information encoded in one light ray to others, thus imparting photo‐optical modulation on the orthogonal light beam.
Biocidal action of copolymers based on aliphatic diamines and guanidine hydrochloride
Authors: Nikolaevna Grigor'eva Maria , Aleksandrovich Stel'makh Sergey , Aleksandrovna Astakhova Svetlana , Mihaylovna Tsenter Irina , Ulzitovna Bazaron Larisa , Babudorjievich Batoev Valeriy , Markovich Mognonov Dmitry 
Published: January 2014

ABSTRACTCopolymers of polyguanidines with various lengths of hydrocarbon radicals were obtained by polycondensation. The biocidal action of water‐soluble, guanidine‐containing copolymers on the pathogenic microorganisms Escherichia coli and Bacillus cereus by the method of agar diffusion was evaluated. The results indicate that the ratio of hydrophobic methylene groups to ionogen guanidine groups influenced the copolymer biocidal action. © 2014 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2014, 131, 40319.
Synthesis of poly(4‐aminophenol) by horseradish peroxidase and the evaluation of its adsorptivity for silver ions
Authors: Duan Hua , Zheng Ke , Zhang Lei , Cui Yuanchen 
Published: January 2014

ABSTRACTIn this study, poly(4‐aminophenol) was successfully prepared by an enzymatic reaction in water, with its molecular weights ranging from 12,000 to 52,000. The polymerization of 4‐aminophenol produced high yields over a wide pH ranging from 4 to 10. In addition, poly(4‐aminophenol) was also used for silver‐ion adsorption because it was composed of amino and hydroxyl groups. We found that the adsorption capacity of poly(4‐aminophenol) was relevant to the time, pH value, temperature, and concentration of silver ions, and the greatest adsorption capacity of poly(4‐aminophenol) for silver ions was 220 mg/g. Moreover, a series of tests showed that the adsorption of silver ions was mainly achieved by a reduction reaction, and the silver nanoparticles were formed with a face‐centered cubic structure, and their average particle size was about 10 nm. © 2014 Wiley Periodicals, Inc. J. Appl. Polym. Sci.2014,131, 40367.
Cellular redox homeostasis in endothelial cells treated with nonmodified and Fenton‐modified nanodiamond powders
Authors: Solarska‐Ściuk K. , Gajewska A. , Skolimowski J. , Gajek A. , Bartosz G. 
Published: January 2014

AbstractDiamond nanoparticles find numerous applications in pharmacy, medicine, cosmetics, and biotechnology. However, possible adverse cellular effects of diamond nanoparticle cells have been reported, which may limit their use. The aim of this study was to compare the effect of nonmodified diamond nanoparticles (D) and diamond nanoparticles modified by the Fenton reaction (D+OH) on human umbilical cord endothelial cells (HUVEC‐ST). We found that both D and D+OH show time‐ and concentration‐dependent cytotoxicity, inducing apoptosis and necrosis of HUVEC‐ST. Interaction with D and D+OH also induced changes in the production of reactive oxygen and nitrogen species and changes in the level of glutathione and activities of antioxidant enzymes in the cells. These data demonstrate that diamond nanoparticles may induce oxidative stress in human endothelial cells, which contributes to their cytotoxic effects seen at higher concentrations of D and D+OH.
A paternal environmental legacy: Evidence for epigenetic inheritance through the male germ line
Authors: Soubry Adelheid , Hoyo Cathrine , Jirtle Randy L. , Murphy Susan K. 
Published: January 2014

AbstractLiterature on maternal exposures and the risk of epigenetic changes or diseases in the offspring is growing. Paternal contributions are often not considered. However, some animal and epidemiologic studies on various contaminants, nutrition, and lifestyle‐related conditions suggest a paternal influence on the offspring's future health. The phenotypic outcomes may have been attributed to DNA damage or mutations, but increasing evidence shows that the inheritance of environmentally induced functional changes of the genome, and related disorders, are (also) driven by epigenetic components. In this essay we suggest the existence of epigenetic windows of susceptibility to environmental insults during sperm development. Changes in DNA methylation, histone modification, and non‐coding RNAs are viable mechanistic candidates for a non‐genetic transfer of paternal environmental information, from maturing germ cell to zygote. Inclusion of paternal factors in future research will ultimately improve the understanding of transgenerational epigenetic plasticity and health‐related effects in future generations.
Transfer and functional consequences of dietary microRNAs in vertebrates: Concepts in search of corroboration
Authors: Witwer Kenneth W. , Hirschi Kendal D. 
Published: January 2014

If validated, diet‐derived foreign microRNA absorption and function in consuming vertebrates would drastically alter our understanding of nutrition and ecology. RNA interference (RNAi) mechanisms of Caenorhabditis elegans are enhanced by uptake of environmental RNA and amplification and systemic distribution of RNAi effectors. Therapeutic exploitation of RNAi in treating human disease is difficult because these accessory processes are absent or diminished in most animals. A recent report challenged multiple paradigms, suggesting that ingested microRNAs (miRNAs) are transferred to blood, accumulate in tissues, and exert canonical regulation of endogenous transcripts. Independent replication of these findings has been elusive, and multiple disconfirmatory findings have been published. In the face of mounting negative results, any additional positive reports must provide the proverbial “extraordinary proof” to support such claims. In this article, we review the evidence for and against a significant role for dietary miRNAs in influencing gene expression, and make recommendations for future studies.Also watch the Video Abstract
Biosynthetic Origin of the Antibiotic Cyclocarbamate Brabantamide A (SB‐253514) in Plant‐Associated Pseudomonas.
Authors: Schmidt Yvonne , van der Voort Menno , Crüsemann Max , Piel Jörn , Josten Michaele , Sahl Hans‐Georg , Miess Henrike , Raaijmakers Jos M. , Gross Harald 
Published: January 2014

AbstractWithin the framework of our genome‐based program to discover new antibiotic lipopeptides from Pseudomonads, brabantamides A–C were isolated from plant‐associated Pseudomonas sp. SH‐C52. Brabantamides A–C displayed moderate to high in vitro activities against Gram‐positive bacterial pathogens. Their shared structure is unique in that they contain a 5,5‐bicyclic carbamate scaffold. Here, the biosynthesis of brabantamide A (SB‐253514) was studied by a combination of bioinformatics, feeding experiments with isotopically labelled precursors and in vivo and in vitro functional analysis of enzymes encoded in the biosynthetic pathway. The studies resulted in the deduction of all biosynthetic building blocks of brabantamide A and revealed an unusual feature of this metabolite: its biosynthesis occurs via an initially formed linear di‐lipopeptide that is subsequently rearranged by a novel FAD‐dependent Baeyer–Villiger monooxygenase.
ChemInform Abstract: β‐Technetium Dichloride: Solid‐State Modulated Structure, Electronic Structure, and Physical Properties.
Authors: Sattelberger Alfred P. , et al. et al. 
Published: January 2014

Abstractβ‐TcCl2 is synthesized by reaction of Tc metal and Cl2 in a sealed Pyrex tube at 450 °C for 24 h, and characterized by single crystal XRD, magnetic susceptibility, band gap, and charge transport measurements, and DFT calculations.
ChemInform Abstract: Electronic and Ionic Conductivity in Alkaline Earth Diazenides MAEN2 (MAE: Ca, Sr, Ba) and in Li2N2.
Authors: Schneider Sebastian B. , Mangstl Martin , Friederichs Gina M. , Frankovsky Rainer , Schmedt auf der Guenne Joern , Schnick Wolfgang 
Published: January 2014

Abstract6Li2N2, nondoped Li2N2 (I), SrN2 (II), and BaN2 (III) are prepared from their respective azides by high pressure isostatic hot pressing (multianvil press, 9 GPa for (I) and (II), 3 GPa for (III), 750—850 K, 15—50 min).
ChemInform Abstract: A Rapid Microwave‐Assisted Solvothermal Approach to Lower‐Valent Transition Metal Oxides.
Authors: Moorhead‐Rosenberg Zachary , Harrison Katharine L. , Turner Travis , Manthiram Arumugam 
Published: January 2014

AbstractBinary oxides such as V4O9, Mn3O4 or MnO, CoO, and Cu2O are prepared within a short reaction time of 30 min by reduction of V2O5, MnO2, Co3O4, or CuO with tetraethylene glycol under microwave irradiation at <300 °C.
ChemInform Abstract: Hydrothermal Preparation, Structure and Characterizations of Noncentrosymmetric LiZnO(IO3).
Authors: Gao Jianhua , Li Shuai , Li Jian , Sanjeewa Liurukara Duminda 
Published: January 2014

AbstractThe new title compound is hydrothermally prepared from aqueous mixtures of ZnO, Li2CO3, and HIO3 (autoclave, 200 °C, 7 d, 80% yield).
ChemInform Abstract: Crystal Structures and Properties of Europium Aluminum Oxynitride Eu2AlO3.75N0.1 and Europium Aluminum Oxide EuAl2O4.
Authors: Tezuka Keitaro , Tokuhara Yoshimi , Wakeshima Makoto , Shan Yue Jin , Imoto Hideo , Hinatsu Yukio 
Published: January 2014

AbstractEu2AlO3.75N0.1 (I) and EuAl2O4 (II) are synthesized by reaction of Eu2O3, AlN, and Al2O3 with Eu/Al ratios of 2:1 and 1:2, respectively (silica tubes, 1200 °C, 10 h).
ChemInform Abstract: Y2MoSe3O12 and Y2MoTe3O12: Solid‐State Synthesis, Structure Determination, and Characterization of Two New Quaternary Mixed Metal Oxides Containing Asymmetric Coordination Environment.
Authors: Bang Seong‐eun , Pan Zhi , Kim Yeong Hun , Lee Dong Woo , Ok Kang Min 
Published: January 2014

AbstractY2MoSe3O12 (I) and Y2MoTe3O12 (II) are prepared by solid state reactions of stoichiometric amounts of Y2O3, MoO3, and SeO2 or TeO2 (evacuated silica tubes, 700 resp.
ChemInform Abstract: Arylations of Substituted Enamides by Aryl Iodides: Regio‐ and Stereoselective Synthesis of (Z)‐β‐Amido‐β‐Arylacrylates.
Authors: Gou Quan , Deng Bin , Zhang Hongbin , Qin Jun 
Published: January 2014

AbstractThe use of the unusual catalyst system PdCl2(cod)/Ag3PO4 and the assistance of a directing carbonyl group allow the highly regio‐ and stereoselective reaction of enamides with aryl iodides to give the corresponding (Z)‐products.
ChemInform Abstract: Free‐Amine Directed Arylation of Biaryl‐2‐amines with Aryl Iodides by Palladium Catalysis.
Authors: Liang Zunjun , Feng Ruokun , Yin Hong , Zhang Yuhong 
Published: January 2014

AbstractThe title method allows the synthesis of ortho‐monoarylated or diarylated biaryl‐2‐amines with exclusive regioselectivity.
ChemInform Abstract: Diaminophosphine Oxide Ligand Enabled Asymmetric Nickel‐Catalyzed Hydrocarbamoylations of Alkenes.
Authors: Donets Pavel A. , Cramer Nicolai 
Published: January 2014

AbstractThe novel chiral diaminophosphine oxide ligand SPO is used in a catalytic system in combination with nickel(0) and trimethylaluminum to activate formamide C—H bonds under mild conditions providing pyrrolidones via intramolecular hydrocarbamoylation.
ChemInform Abstract: Pd(II)‐Catalyzed Intramolecular 1,2‐Aminoalkylation of Conjugated 1,3‐Dienes for the Synthesis of Pyrrolizidines.
Authors: Xing Dong , Yang Dan 
Published: January 2014

AbstractA palladium(II)‐catalyzed tandem cyclization reaction involving an intramolecular 1,2‐aminoalkylation of N‐4,6‐dienyl β‐keto amides is developed.
ChemInform Abstract: Synthesis of New Pyrazole‐1,2,3‐triazole Dyads.
Authors: Ferreira Joana P. A. , Silva Vera L. M. , Elguero Jose , Silva Artur M. S. 
Published: January 2014

AbstractUpon reaction with hydrazine hydrate, previously described chromon‐2‐yl‐1H‐1,2,3‐triazoles (I) afford title compounds (II).
ChemInform Abstract: β‐Lactam‐Synthon‐Interceded Synthesis of Isatin—Imidazolidine‐2‐thione Conjugates with Structural Validation Using Molecular Dynamic Simulations and Cytotoxic Evaluation.
Authors: Nisha Nisha , Singh Parvesh , Hendricks Denver T. , Bisetty Krishna , Kumar Vipan 
Published: January 2014

AbstractThe anion derived from isatins (I) reacts with isocyanates (II) to form imidazolidine‐2‐thiones (III), some of which show significant cytotoxic activity against the oesophageal cancer cell line WHCO1.
ChemInform Abstract: Efficient Multicomponent Synthesis of Mono‐, Bis‐, Tris‐1,2,3‐triazoles Supported by Hydroxybenzene Scaffolds.
Authors: Mendoza‐Espinosa Daniel , Negron‐Silva Guillermo E. , Lomas‐Romero Leticia , Gutierrez‐Carrillo Atilano , Soto‐Castro Delia 
Published: January 2014

AbstractStarting from mono‐, di‐, and tripropargyloxybenzenes the synthesis of the title species is achieved via 1,3‐dipolar cycloaddition reaction with sodium azide and benzyl halides.
ChemInform Abstract: Copper‐Catalyzed Tandem Azide—Alkyne Cycloaddition, Ullmann Type C—N Coupling, and Intramolecular Direct Arylation.
Authors: Pericherla Kasiviswanadharaju , Jha Amitabh , Khungar Bharti , Kumar Anil 
Published: January 2014

AbstractNovel triazole‐fused heterocycles are regioselectively obtained via a ligand‐free copper‐catalyzed tandem azide—alkyne cycloaddition (CuAAC), Ullmann‐type C—N coupling reaction and subsequent intramolecular C—C bond formation by C—H functionalization.
ChemInform Abstract: Catalytic Asymmetric Construction of Chiral Hydropyridazines via Conjugate Addition of N‐Monosubstituted Hydrazones to Enones.
Authors: Wu Wenbin , Yuan Xiaoqian , Hu Juan , Wu Xinxin , Wei Yuan , Liu Zunwu , Lu Junzhu , Ye Jinxing 
Published: January 2014

AbstractThe first examples of a highly enantioselective formal diaza‐ene reaction between N‐monosubstituted hydrazones and enones are reported.
ChemInform Abstract: Synthesis of 3‐Tetrazolylmethyl‐azepino[4,5‐b]indol‐4‐ones in Two Reaction Steps: (Ugi‐Azide/N‐Acylation/SN2)/Free Radical Cyclization and Docking Studies to a 5‐Ht6 Model.
Authors: Gordillo‐Cruz Raul E. , Renteria‐Gomez Angel , Islas‐Jacome Alejandro , Cortes‐Garcia Carlos J. , Diaz‐Cervantes Erik , Robles Juvencio , Gamez‐Montano Rocio 
Published: January 2014

AbstractNine novel 3‐tetrazolylmethyl‐azepinoindolones (VII) are synthesized starting from tryptamine (I) and evaluated for their interactions with the 5‐Ht6 protein.
ChemInform Abstract: Biomimetic Synthesis of ent‐(—)‐Azonazine and Stereoochemical Reassignment of Natural Product.
Authors: Zhao Ji‐Chen , Yu Shun‐Ming , Liu Yun , Yao Zhu‐Jun 
Published: January 2014

AbstractThe first total synthesis of ent‐(‐)‐azonazine (I) is accomplished using a hypervalent iodine‐mediated biomimetic oxidative cyclization to construct the highly strained core (not shown).
ChemInform Abstract: Antiviral Spirooliganones A (I) and B (II) with Unprecedented Skeletons from the Roots of Illicium oligandrum.
Authors: Yu Shi‐Shan , et al. et al. 
Published: January 2014

AbstractThe two isolated compounds show obvious activities against coxsackie virus B3 and influenza virus A, whereas spirooliganone B is the more potent one (IC50 3.70‐5.05 μM).
ChemInform Abstract: Expanding the Scope of Metathesis: A Survey of Polyfunctional, Single‐Site Supported Tungsten Systems for Hydrocarbon Valorization
Authors: Popoff Nicolas , Mazoyer Etienne , Pelletier Jeremie , Gauvin Regis M. , Taoufik Mostafa 
Published: January 2014

AbstractReview: 122 refs.
ChemInform Abstract: Tunable Assembly of Amphiphilic Rod‐Coil Block Copolymers in Solution
Authors: Zhang Jie , Chen Xiao‐Fang , Wei Hai‐Bing , Wan Xin‐Hua 
Published: January 2014

AbstractReview: valuable contribution in the past six years on the self‐assembly behavior of rod‐coil block copolymers; 239 refs.
Structural Basis for the Inhibition of AKR1B10 by Caffeic Acid Phenethyl Ester (CAPE)
Authors: Zhang Liping , Zhang Hong , Zheng Xuehua , Zhao Yining , Chen Shangke , Chen Yunyun , Zhang Renwei , Li Qing , Hu Xiaopeng 
Published: January 2014

AbstractCaffeic acid phenethyl ester (CAPE), the major bioactive component of honeybee propolis, is a potent selective inhibitor of aldo‐keto reductase family member 1B10 (AKR1B10), and a number of derivatives hold promise as potential anticancer agents. However, sequence homology between AKR1B10 and other members of the superfamily, including critical phase I metabolizing enzymes, has resulted in a concern over the selectivity of any potential therapeutic agent. To elucidate the binding mode of CAPE with AKR1B10 and to provide a tool for future in silico efforts towards identifying selective inhibitors, the crystal structure of AKR1B10 in complex with CAPE was determined. The observed interactions provide an explanation for the selectivity exhibited by CAPE for AKR1B10, and could be used to guide further derivative design.
Comparative effectiveness of upfront treatment strategies in elderly women with ovarian cancer
Authors: Wright Jason D. , Ananth Cande V. , Tsui Jennifer , Glied Sherry A. , Burke William M. , Lu Yu‐Shiang , Neugut Alfred I. , Herzog Thomas J. , Hershman Dawn L. 
Published: January 2014

BACKGROUNDObservational studies comparing neoadjuvant chemotherapy to primary surgery for advanced‐stage ovarian cancer are limited by strong selection bias. Multiple methods were used to control for confounding and selection bias to estimate the effect of primary treatment on survival for ovarian cancer.METHODSThe Surveillance, Epidemiology, and End Results (SEER)‐Medicare database was used to identify women ≥ 65 years of age with stage II‐IV epithelial ovarian cancer who survived > 6 months from the date of diagnosis and received treatment from 1991 through 2007. Traditional regression analysis, propensity score‐based analysis, and an instrumental variable analysis (IVA) using geographic location as an instrument were used to compare survival between neoadjuvant chemotherapy and primary surgery.RESULTSA total of 9587 patients with stage II‐IV ovarian cancer were identified. Use of primary surgery decreased from 63.2% in 1991 to 49.5% by 2007, whereas primary chemotherapy increased from 19.7% in 1991 to 31.8% in 2007 (P < .0001). In the observational cohort survival (hazard ratio [HR] = 1.27; 95% confidence interval [CI] = 1.19−1.35) was inferior for patients treated with neoadjuvant chemotherapy; both median survival (15.8 versus 28.8 months) and 2‐year survival (36% versus 56%) were lower in the neoadjuvant chemotherapy group compared to those who underwent surgery. In the IVA, primary treatment had minimal effect on overall survival (HR = 1.04; 95% CI = 0.67−1.60). The median survival for patients with a value of the instrument less than the median (24.0 months, 95% CI = 23.0−25.0) and greater than or equal to median value of the IV (24.0 months, 95% CI = 23.0−26.0) were similar.CONCLUSIONSUse of neoadjuvant therapy has increased over time. Survival with neoadjuvant chemotherapy did not differ significantly from primary surgery in elderly women in the United States. Cancer 2014;120:1246–1254. © 2014 American Cancer Society.