bluuebunny/crossref_metadata_2025_split huggingface dataset:
Overview of issues, challenge, and potential ground water extraction for Kelantan people.
Authors: Noh Narita , Asfar Juwita , Rahim Noor Raifana Ab , Darwis Nur Zaidani Wati Mohd 
Published: July 2024

Abstract
Clean water is a vital element in humankind’s ecosystem for sustainability of living on earth. Limitation of surface water in Kelantan leads toward ground water extraction as an alternative for water supply. However, there are issues and challenges with the current practice including water quality index (WQI), pollution and monitoring of capacity extraction for ground water. Thus, the objective of this paper is to summary the current scenario of ground water extraction in Kelantan. Hence, identify the potential problems that occur based on current practice and look forward for potential ground water extraction in Kelantan in future. This finding is extracted from previous study done by other researchers, or any electronic media related to the objective of the paper. Due to limited source of indexed paper, Google, official related agencies website and ResearchGate are being adopted as main platforms for search engines for data and literature needed. It is hoped that these findings would be able to help authority and relevant parties to improve the framework and government policy for groundwater extraction in Kelantan. It is also viewed to help Kelantanese to have better ground water supply as stipulated by Ministry of Health.
Double Hanle resonance dependence on light polarization angle and transverse magnetic field direction
Authors: Kumari Pooja , Mehta Shrey , Singh Grewal Raghwinder , Singh R P 
Published: July 2024

Abstract
We present experimental and theoretical investigations of the dependence of double Hanle resonance spectrum on the light polarization angle and the direction of the applied transverse magnetic field (TMF). The experiments are done for

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transition of 87Rb D1 line using a rubidium vapor cell containing buffer gas. We show that a small light polarization component along the direction of TMF introduces asymmetry in the double Hanle resonance signal. Both the magnitude and sign of asymmetry in the signal are sensitive to the TMF orientation, suggesting a possible method for in-situ measurement of the direction of the magnetic fields generated by the coils. The physical origin of this asymmetry is explained by considering the redistribution of population among the ground-state Zeeman sublevels in the presence of TMF. In addition, we systematically vary both the polarization angle and TMF direction to study their effect on the line profile of Hanle resonances. We demonstrate that a double Hanle resonance changes to a dark Hanle resonance by rotating the light polarization vector irrespective of the TMF direction. We have developed a simple theoretical model based on a degenerate two-level system to explain our experimental observations.
Internal to What? A Novel Account of the Task of Political Liberalism
Authors: Badano Gabriele , Nuti Alasia 
Published: July 2024

Abstract
This chapter advances a novel account of the purpose of Rawlsian political liberalism. The prominent ‘internal view’ of political liberalism conceives of it as meant to establish liberalism’s internal coherence; political liberals’ job is to show that legitimate and stable liberal institutions are possible despite the reasonable pluralism they fuel. On this view, the scope of political liberalism only includes societies characterized by reasonable pluralism and reasonable pluralism arises exclusively in well-ordered ideal liberal societies, which are governed by reasonable liberal justice and inhabited only by reasonable citizens. Therefore, the very project of investigating the containment of unreasonable beliefs is effectively thrown out of political liberalism properly understood. We criticize this view by arguing that it misunderstands the notion of reasonable pluralism, which features also in non-ideal ‘minimally liberal’ societies. Consequently, the purpose of political liberalism should also include showing how minimally liberal societies can move closer to a reasonably just society overwhelmingly populated by reasonable persons without contradicting any basic liberal democratic commitments. In turn, this makes understanding containment a priority. The resulting view of political liberalism, which we label the view ‘internal to at least minimally liberal societies’, remains safe from the traditional objections the internal view was created to sidestep. In defending such a view, we also propose an original methodological approach, according to which ideal and non-ideal theory are both important but largely independent projects within political liberalism. This broad independence of non-ideal from ideal theory constitutes an important building block of our politicized political liberalism.
The Folk Theory of Well-Being
Authors: Bronsteen John , Leiter Brian , Masur Jonathan S , Tobia Kevin 
Published: July 2024

Abstract
What constitutes a “good” life—not necessarily a morally good life, but a life that is good for the person who lived it? In response to this question of “well-being,” philosophers have offered three significant answers: A good life is one in which a person can satisfy their desires (“Desire-Satisfaction” or “Preferentism”), one that includes certain good features (“Objectivism”), or one in which pleasurable states dominate or outweigh painful ones (“Hedonism”). This chapter presents a pair of experimental studies that examine whether the three theories reflect laypeople’s intuitions about well-being. The empirical studies yield two primary findings. First, they provide evidence for lay “well-being pluralism”: laypeople treat desire-satisfaction, positive objective conditions, and happiness as all constitutive of well-being. Second, the studies provide evidence of “hedonic dominance”: laypeople evaluate an individual’s happiness as more important to an individual’s overall well-being than desire-satisfaction or objective conditions.
Practices Make Perfect
Authors: Alexander Joshua , Weinberg Jonathan M 
Published: July 2024

Abstract
This chapter argues that debates over philosophical methodology would be well-served by a greater attention to the specifics of philosophical practice. Intuition deniers such as Max Deutsch and Herman Cappelen have claimed that philosophers do not generally rely on intuitions, but simply make arguments, perhaps elliptical ones. Their claims turn out to be inconsistent with, for example, the sorts of dialectical moves that are licensed in philosophical practice when mooting a case; and with much of the historical evidence about the reception of Gettier’s classic paper. Others, like Joshua Knobe, have argued that intuitions are so stable and uniform that a proper reading of the empirical evidence indicates that no methodological concerns should arise. Yet such arguments do not adequately consider just how much current philosophical practices, especially inferential practices, are susceptible to even fairly modest sources of error.
How much could anemia-related interventions reduce the HIV disparity in adverse birth outcomes?
Authors: Caniglia Ellen C , Zash Rebecca , Diseko Modiegi , Mayondi Gloria , Mabuta Judith , Mmalane Mompati , Makhema Joseph , Jacobson Denise L , Bengtson Angela M , Lockman Shahin , Shapiro Roger , Swanson Sonja A 
Published: July 2024

Abstract
Women and other people of childbearing potential living with HIV (WLHIV) have a higher risk of adverse birth outcomes than those without HIV (WWHIV). A higher risk of anemia in WLHIV could partially explain this disparity. Using a birth outcomes surveillance study in Botswana, we emulated target trials corresponding to currently available or feasible interventions on anemia. The first target trial evaluated 2 interventions: initiate multiple micronutrient supplementation (MMS), and MMS or iron and folic acid supplementation by 24 weeks gestation. The remaining target trials evaluated the interventions: eliminate anemia before pregnancy; and jointly eliminate anemia before pregnancy and initiate MMS. We estimated the observed disparity in adverse birth outcomes between WLHIV and WWHIV and compared the observed disparity measure (ODM) to the counterfactual disparity measure (CDM) under each intervention. Of 137 499 individuals (22% WLHIV), the observed risk of any adverse birth outcome was 26.0% in WWHIV and 34.5% in WLHIV (ODM, 8.5%; 95% confidence interval [CI], 7.9-9.1%). Counterfactual disparity measures (95% CIs) ranged from 6.6% (4.8-8.4%) for the intervention to eliminate anemia and initiate MMS to 8.4% (7.7%-9.1%) for the intervention to eliminate anemia only. Preventing anemia and expanding MMS may reduce HIV disparities in birth outcomes, but interventions with greater impact should be identified.
Prediagnostic whole-blood cadmium and molybdenum associated with pancreatic cancer in an American cohort
Authors: Stolzenberg-Solomon Rachael , Jin David , Huang Wen-Yi , Brockman John 
Published: July 2024

Abstract
Environmental exposures to elements such as cadmium might be contributing to the increasing incidence of pancreatic cancer. Few prospective studies have examined the association between trace elements and pancreatic ductal adenocarcinoma (PDAC). We conducted a nested case-control study in participants aged 55-74 years at baseline from the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial cohort to examine the association between 12 trace elements measured in prediagnostic whole-blood samples and PDAC. From May 1998 through December 2014, 318 incident PDAC cases were identified during follow-up to 16.7 years. Of 636 control participants, 2 who were alive when each case patient was diagnosed were selected and matched by age (±5 years), sex, calendar date of blood sample collection (2-month blocks), and race and ethnic group. We used multivariable adjusted conditional logistic regression to calculate odds ratios (ORs) and 95% CIs. Cadmium and molybdenum were associated with PDAC (highest compared with lowest quintile: for cadmium, OR = 1.81 [95% CI, 01.12-2.95], P = .03 for trend; for molybdenum, OR = 0.50 [95% CI, 0.32-0.80], P = .02 for trend). The inverse molybdenum association was only observed among ever smokers (OR = 0.31 [95% CI, 0.17-0.58]; P = .003 for trend, P = .03 for interaction) with no association in never smokers. Lead, arsenic, and other trace elements were not associated with PDAC. Our results support that an increasing prediagnostic whole-blood level of cadmium is associated with increased PDAS risk, whereas that for molybdenum reduces PDAC risk.
PlasmidHunter: accurate and fast prediction of plasmid sequences using gene content profile and machine learning
Authors: Tian Renmao , Zhou Jizhong , Imanian Behzad 
Published: July 2024

Abstract
Plasmids are extrachromosomal DNA found in microorganisms. They often carry beneficial genes that help bacteria adapt to harsh conditions. Plasmids are also important tools in genetic engineering, gene therapy, and drug production. However, it can be difficult to identify plasmid sequences from chromosomal sequences in genomic and metagenomic data. Here, we have developed a new tool called PlasmidHunter, which uses machine learning to predict plasmid sequences based on gene content profile. PlasmidHunter can achieve high accuracies (up to 97.6%) and high speeds in benchmark tests including both simulated contigs and real metagenomic plasmidome data, outperforming other existing tools.
Reproductive & developmental toxicity of quaternary ammonium compounds
Authors: Bobic Leyla , Harbolic Allison , Warner Genoa R 
Published: July 2024

Abstract
Quaternary ammonium compounds are a class of chemicals commonly used as disinfectants in household and healthcare settings. Their usage has significantly increased in recent years due to the COVID-19 pandemic. In addition, quaternary ammonium compounds have replaced the recently banned disinfectants triclosan and triclocarban in consumer products. Quaternary ammonium compounds are found in daily antimicrobial and personal care products such as household disinfectants, mouthwash, and hair care products. Due to the pervasiveness of quaternary ammonium compounds in daily use products, humans are constantly exposed. However, little is known about the health effects of everyday quaternary ammonium compound exposure, particularly effects on human reproduction and development. Studies that investigate the harmful effects of quaternary ammonium compounds on reproduction are largely limited to high-dose studies, which may not be predictive of low-dose, daily exposure, especially as quaternary ammonium compounds may be endocrine-disrupting chemicals. This review analyzes recent studies on quaternary ammonium compound effects on reproductive health, identifies knowledge gaps, and recommends future directions in quaternary ammonium compound–related research.
Summary Sentence
Quaternary ammonium compounds, a class of disinfecting compounds that have skyrocketed in usage during the COVID-19 pandemic, are emerging as reproductive and developmental toxicants.
The Holocaust Propaganda Machine in Soviet Periodicals, 1941–1945
Authors: Kaganovitch Albert 
Published: July 2024

Abstract
The USSR entered the Second World War with the world’s most powerful propaganda apparatus, having twenty years of experience and a state monopoly on truth.1 All publications were subjected to a three-tiered system of censorship: personal, editorial, and official, with the common line of censorship determined at the highest level. In the Soviet Union, there were five primary sources of official information: (a) periodical publications, (b) fictional literature, (c) journalistic writing, (d) films, and (e) radio broadcasts. The author examines the Russian language periodical press, which was the most widely available print material in the USSR. These sources were entirely aimed at Soviet readers, as opposed to Yiddish-language publications, which were in part intended to arouse sympathy in readers abroad.2 Verification of casualty statistics and authenticating the facts of this published information is not the purpose of this article, but rather the author seeks to challenge the assumption that the USSR suppressed or censored reporting on the Holocaust during the Second World War.
O-001 Human Reproduction Keynote lecture: Progesterone for pregnant people with threatened miscarriage
Authors: Li W , McLindon L , Mol B 
Published: July 2024

Abstract
Threatened miscarriage, characterized by vaginal bleeding in early pregnancy, affects approximately 25% of all clinical pregnancies. Progesterone supplementation, typically administered vaginally, is a common clinical practice aimed at preventing miscarriage in cases of threatened miscarriage. However, the evidence regarding the effectiveness of this intervention is conflicting and subject to varying interpretations. In a randomized controlled trial conducted in Queensland, Australia, we evaluated the efficacy of nightly 400 mg vaginal progesterone administration, initiated at the onset of bleeding and continued until 12 weeks gestation, in increasing live birth rates among women experiencing threatened miscarriage. Our study did not find evidence supporting a treatment effect of vaginal progesterone in enhancing live birth rates, nor did we find evidence that progesterone improves live birth rates in women with a history of two or more previous miscarriages. We conclude that routine use of progesterone for threatened miscarriage cannot be recommended. However, the potential therapeutic benefit of progesterone in women with threatened miscarriage following recurrent pregnancy losses warrants further investigation through dedicated clinical trials in this population.
O-045 Does PGT improve outcomes in poor responders?
Authors: Ginsburg E 
Published: July 2024

Abstract
All studies randomizing women to undergo PGT-A or transfer of untested embryos are in patients with excellent blastocyst quality. No studies show that PGT-A improves live birth rate per stimulated cycle, only per embryo transfer in patients fortunate to have high quality blastocysts. There are also no randomized trials of cleavage stage vs blastocyst transfer in patients with fewer than 4 embryos. Normal babies have been reported after transfer of aneuploid (not only mosaic) embryos. Patients with decreased ovarian reserve have high chances of no embryo transfer and therefore no chance of pregnancy if they chose to undergo IVF with PGT-A.
O-099 Implantation 2024 - what do we know?
Authors: Quenby S 
Published: July 2024

Abstract
Three major factors are involved in implantation, the embryo, the endometrium and the microbiome. The interactions between these major participants need to, support normal pregnancies and reject abnormal ones and have an appropriate pro/anti-inflammatory response to the genital tract microbiome. Implantation is controlled by a series biological checks and balances in the context of an endometrium that regenerates monthly. Our understanding of these checks and balances has been advanced with the use of sequencing technologies.
• The high incidence of aneuploidy in early human embryos has been described in detail with low-coverage sequencing- based PGT-A.
• The contribution of karyotype abnormality to miscarriages has been clarified with the use of a microarray-based comparative genomic hybridisation and the cell free DNA.
• New insights into endometrial composition have been made through single cell sequencing that has revealed the existence of new subsets of cells at the maternal fetal interface.
• The genital tract microbiome has been investigated using high-throughput next-generation sequencing of bacterial 16S rRNA genes.
This rich tapestry of information has revealed the complexity of cellular and molecular process controlling implantation. The challenge is to identify specific mechanisms and therapeutic targets for couples suffering reproductive failure.
O-105 Contribution of ART to fertility rates and family size
Authors: Chambers G , Lazzari E 
Published: July 2024

Abstract
In the last three decades declining fertility has become an increasing global trend. One-half of the global population today lives in countries where the period Total Fertility Rate is below 2.1 births per woman. Many countries in Europe and Asia are experiencing “ultra-low” fertility rates of 1.0-1.4 births per woman. This decline in births creates both social and economic challenges.
In addition, most countries have gone through a long period of increasing average age at birth. The shift in births at older ages has been accompanied by a concomitant decline in completed family size. As the average age at having children has increased over time, the proportion of women experiencing difficulty in achieving a pregnancy has also increased, with assisted reproductive technology (ART) treatments becoming increasingly important in counteracting this decline. However, the demographic impact of ART widely varies across countries, with the proportion of babies born as a result of ART, ranging from almost 10% of birth in in some European countries to &lt; 1% in Latin America and 2% in the USA.
ART is increasingly being raised as a potential policy tool to increase fertility. While ART can broaden the range of possible responses to low fertility rates, there are a number of challenges in quantifying contribution to fertility rates. There are also a number of important unintended consequences that need to be taken into account when trying to estimate their effectiveness as a policy tool to increase fertility.
In this presentation, the evidence for the contribution of ART to total and age-specific fertility rates in different settings will be summarized and compared with other pronatalist policies. The contribution of ART and other forms of fertility treatment to completed family size and childbearing timing will also be described and discussed. Assisted reproduction is making a modest and increasing contribution to the fertility rate of high-income countries, but its potential impact should not be overestimated.
O-110 Adenomyosis : the challenge of classification and diagnosis
Authors: Feki A , Acien M , As Sanie S , De Wilde R L , Gordts S , Guo S -W , Keckstein J , Laganà A S , Leone Roberti Maggiore U , Nisolle M , Saridogan E , Stewart E A , Tellum T , Tomassetti C , Johnson N , Le Clef N , Grimbizis G 
Published: July 2024

Abstract

Study question
What does the collaborative document on adenomyosis terminology, classification, and diagnosis by ESGE, ESHRE, and WES provides?

Summary answer
This good practice recommendations paper offers guidance on the technical aspects, terminology, classification, and diagnosis of adenomyosis in women of reproductive age.

What is known already
The existing literature on adenomyosis terminology is heterogeneous and confusing. Various classification systems based on ultrasound and MRI have been proposed, yet none have gained international acceptance or clinical validation. The contradictory data on the diagnostic accuracy of these modalities further complicate adenomyosis diagnosis in reproductive-age women.

Study design, size, duration
A working group from ESGE, ESHRE, and WES has collaborated to write recommendations concerning the terminology, classification, and diagnosis of adenomyosis.

Participants/materials, setting, methods
Focusing on terminology, classification, and diagnosis, this good practice paper paves the way for further recommendations on the management and surgical treatment of adenomyosis in reproductive-age women.

Main results and the role of chance
The document overviews adenomyosis terminology and reviews proposed classification systems based on histology, ultrasound, and MRI, concluding with diagnostic recommendations.

Limitations, reason for caution
Owing the scarcity of evidence, these recommendations predominantly rely on clinical expertise.

Wider implications of the findings
The recommendations aim to enhance existing adenomyosis guidelines.

Study funding/Competing interests
All costs were covered by ESHRE funds, with no external funding for the development process or manuscript production.
O-119 Architecture and in situ arrangement of the CatSper-channel complex in the sperm flagellum
Authors: Chung J J 
Published: July 2024

Abstract
The sperm calcium channel CatSper plays a central role in successful fertilization as a primary Ca2+ gateway. Here, we applied cryo-electron tomography to visualize the higher-order organization of the native CatSper complex in intact mammalian sperm. The repeating CatSper units form long zigzag-rows along mouse and human sperm flagella. Above each tetrameric channel pore, most of the extracellular domains form a canopy that interconnects to a zigzag-shaped roof. Murine CatSper contains an additional wing-structure connected to the tetrameric channel. The intracellular domains link two neighboring channels to a diagonal array, suggesting a dimer formation. Fitting of an atomic model of isolated monomeric CatSper to the in situ map reveals supramolecular interactions and assembly of the CatSper complex. Loss of EFCAB9-CATSPERζ alters the architecture and interactions of the channels, resulting in fragmentation and misalignment of the zigzag-rows and disruption of flagellar movement in Efcab9−/− sperm. This work offers unique insights into the structural basis for understanding CatSper regulation of sperm motility.