bluuebunny/crossref_metadata_2025_split huggingface dataset:
A qualitative study identifying implementation strategies using the i-PARIHS framework to increase access to pre-exposure prophylaxis at federally qualified health centers in Mississippi
Authors: Arnold Trisha , Whiteley Laura , Giorlando Kayla K. , Barnett Andrew P. , Albanese Ariana M. , Leigland Avery , Sims-Gomillia Courtney , Elwy A. Rani , Edet Precious Patrick , Lewis Demetra M. , Brock James B. , Brown Larry K. 
Published: August 2024

Abstract
Background
Mississippi (MS) experiences disproportionally high rates of new HIV infections and limited availability of pre-exposure prophylaxis (PrEP). Federally Qualified Health Centers (FQHCs) are poised to increase access to PrEP. However, little is known about the implementation strategies needed to successfully integrate PrEP services into FQHCs in MS.

Purpose
The study had two objectives: identify barriers and facilitators to PrEP use and to develop tailored implementation strategies for FQHCs.

Methods
Semi-structured interviews were conducted with 19 staff and 17 PrEP-eligible patients in MS FQHCs between April 2021 and March 2022. The interview was guided by the integrated-Promoting Action on Research Implementation in Health Services (i-PARIHS) framework which covered PrEP facilitators and barriers. Interviews were coded according to the i-PARIHS domains of context, innovation, and recipients, followed by thematic analysis of these codes. Identified implementation strategies were presented to 9 FQHC staff for feedback.

Results
Data suggested that PrEP use at FQHCs is influenced by patient and clinic staff knowledge with higher levels of knowledge reflecting more PrEP use. Perceived side effects are the most significant barrier to PrEP use for patients, but participants also identified several other barriers including low HIV risk perception and untrained providers. Despite these barriers, patients also expressed a strong motivation to protect themselves, their partners, and their communities from HIV. Implementation strategies included education and provider training which were perceived as acceptable and appropriate.

Conclusions
Though patients are motivated to increase protection against HIV, multiple barriers threaten uptake of PrEP within FQHCs in MS. Educating patients and providers, as well as training providers, are promising implementation strategies to overcome these barriers.
Surgical management of aorto-right atrial fistula induced by Stanford type A aortic dissection: a case report
Authors: Yokoyama Takahito , Tsuda Yasutoshi , Shigehara Katsuyuki , Niside Ryo , Sato Daiki , Nakajima Masato 
Published: August 2024

Abstract
Background
The occurrence of aorto-right atrial fistula in a patient with Stanford type A aortic dissection is exceedingly rare, and the treatment has not been established.

Case presentation
A 60-year-old male presented to the emergency department with acute lumbar pain and, based on contrast-enhanced computed tomography, was diagnosed with Stanford type A aortic dissection. Emergency surgery was performed. Transesophageal echocardiography during the surgery did not reveal an aorto-right atrial fistula. After establishing cardiopulmonary bypass, circulatory arrest was induced, and the primary entry in the proximal ascending aorta for the aortic dissection was identified. The aorta was dissected between the right brachiocephalic artery and the left common carotid artery, and an artificial conduit was anastomosed. After re-establishing circulation, venous blood flow from the dissected area at the base of the aortic root was observed, indicating communication between the aorta and the right atrium. Circulatory arrest was induced again, and the ruptured outer aortic adventitia was repaired by continuous suturing using 5–0 prolene. The atrial fistula was repaired from within the right atrium using 5–0 prolene with felt reinforcement. Thus, successful closure was achieved. Proximal anastomosis and right brachiocephalic artery reconstruction were subsequently performed. Postoperative transesophageal echocardiography revealed no shunt flow and no bleeding from the aortic root. The patient recovered smoothly and was discharged without significant complications.

Conclusions
Aorto-right atrial fistula associated with Stanford type A aortic dissection is rare, and in this case, the shunt blood flow was low, making preoperative diagnosis difficult. However, after intraoperative diagnosis, direct suture was used to complete the treatment, which was a simple and effective method.
The influence of lamination and fracture on the velocity anisotropy of tectonic coals
Authors: Gong Fei , Huang Aner , Kang Wujiang , Shi Suzhen , Zou Guangui , Zhang Zhaoji , Wang Guowei 
Published: August 2024

The elastic anisotropy of coal formations is important for the prediction of unconventional coalbed methane reservoir performance and hydraulic fracturing. Although essential for several geophysical applications, the elastic anisotropy of coals is still poorly understood. Therefore, three sets of cylindrical coal samples are drilled parallel and perpendicular to the bedding plane, and the ultrasonic velocities under different confining pressures are measured in the laboratory. We combine experimental observations and modeling analysis to evaluate the elastic anisotropy of the coals. The results suggest that the velocity of coals parallel to the bedding plane is less sensitive to confining pressure than those perpendicular to the bedding plane. The fracture densities of coals parallel to the bedding plane are much lower than those perpendicular to the bedding plane, and most of the fractures are closed when the pressure is higher than 15 MPa. The organic matter (OM), clay content, and their preferred orientation play dominant roles in velocity anisotropy, and the fracture effect can significantly enhance it. The velocity anisotropy parameters of coals are positively correlated with the OM and clay content, and the preferred orientation of OM and clay plays a significant role in coal anisotropy. The results in this study are helpful in the characterization of the fractures of coals and can provide an important rock-physics basis for microseismic fracture monitoring and reservoir prediction.
A Meta-Analysis of Medication Reduction and Motor Outcomes After Awake Versus Asleep Deep Brain Stimulation for Parkinson Disease
Authors: Li Luyuan , Rae Ali I. , Burchiel Kim J. 
Published: August 2024

BACKGROUND AND OBJECTIVES:
There remains significant debate regarding the performance of deep brain stimulation (DBS) procedures for Parkinson disease (PD) under local or general anesthesia. The aim of this meta-analysis was to compare the clinical outcomes between “asleep” DBS (general anesthesia) and “awake” DBS (local anesthesia) for PD.

METHODS:
We conducted a comprehensive literature review of all published studies on DBS for PD following PRISMA guideline on PubMed and Cochrane library from January 2004 to April 2023. Inclusion criteria included cohort ≥15 patients, clinical outcomes data which included Unified Parkinson's Disease Rating Scale (UPDRS) score and levodopa equivalent daily dosage (LEDD), and ≥3 months of follow-up. Analysis was conducted using Stata software.

RESULTS:
There were 18 articles that met inclusion criteria. On meta-analysis, there were no significant differences between awake or asleep DBS with regard to percent change in UPDRS III “off” med/“on” DBS condition (P = .6) and LEDD score (P = .99). On subgroup analysis, we found that the choice of target had no significant effect on improvement of UPDRS III (P = 1.0) or LEDD (P = .99) change for the asleep vs awake operative approach. There were also no statistically significant differences between microelectrode recording (MER) use and no MER use in postoperative UPDRS III (P = 1.0) or LEDD improvement (P = .90) between awake and asleep surgery.

CONCLUSION:
There was no significant difference in the primary motor outcomes and LEDD improvement between asleep vs awake DBS. The variables of target selection and MER use had no statistically significant impact on outcome. We find that asleep techniques are both safe and effective compared with the awake technique.
Integral Dose or Mean Dose for Predicting Radiosurgery Response in Patients With Trigeminal Neuralgia: A Proposal to Target the Narrowest Part of the Nerve
Authors: Meng Ying , Santhumayor Brandon , Mashiach Elad , Bernstein Kenneth , Gurewitz Jason , Cooper Benjamin T. , Sulman Erik , Silverman Joshua , Kondziolka Douglas 
Published: August 2024

BACKGROUND AND OBJECTIVES:
Stereotactic radiosurgery (SRS) is effective for patients with medically refractory trigeminal neuralgia with a 75%-90% response rate. Consideration of the integral dose (ID) to the target nerve within the 50% isodose line was reported to help select prescription doses to maximize effectiveness and minimize bothersome numbness. The objective of this study was to externally validate the ID as a predictor of outcomes after SRS.

METHODS:
We reviewed the outcomes and parameters of 94 consecutive patients of type 1 trigeminal neuralgia who had SRS for the first time where nerve ID was calculated. 70% of the prescription doses were 80 Gy, with 28% at 85 Gy, and 2% at 70 Gy.

RESULTS:
The median follow-up time was 14.4 months. A total of 85 (90%) patients reported significant pain relief (Barrow Neurological Institute I-III) after initial SRS. The median pain recurrence-free survival was 82 months (95% CI 41.1-NA), and estimates at 1, 3, and 5 years were 80.5%, 65.5%, and 55.9%, respectively. The ID was not significantly associated with initial pain relief, or affect the risk of pain recurrence or sensory dysfunction after SRS using the Cox proportional hazards model. A nerve mean dose ≥65 Gy was associated with a reduced risk of pain recurrence on multivariate analysis (hazard ratio 0.408, P = .039). Twenty (21%) patients experienced sensory dysfunction after SRS with 3 (3%) requiring further medications, which was not correlated with the prescription dose or brainstem maximum dose.

CONCLUSION:
The ID did not predict recurrence-free survival or sensory dysfunction. Our observations suggest improved nerve coverage by the most powerful area of the isocenter, for instance, by targeting a narrower segment if feasible, could result in more durable pain relief. Further studies to validate these findings are needed.
Spatial Distribution of Meningiomas: A Magnetic Resonance Image Atlas
Authors: Patel Ruchit V. , Yao Shun , Aguilar Murillo Efrain , Huang Raymond Y. , Bi Wenya Linda 
Published: August 2024

BACKGROUND AND OBJECTIVES:
The size and anatomic location of meningiomas have been shown to correlate with distinct clinical manifestations, histopathological subtypes, and surgical risk. However, meningioma anatomic origin sites can be obscured in large tumors and those crossing compartments. We therefore sought to apply unbiased lesion mapping to localize intracranial meningioma distributions and their association with biology and grade.

METHODS:
MRI scans, World Health Organization (WHO) grade, and a molecularly Integrated Grade (IG) derived from cytogenetics were analyzed from adult patients with intracranial meningiomas. Semi-automated tumor segmentation was performed on T1-weighted contrast-enhanced MRI. We used the voxel-based lesion mapping technique to generate a meningioma atlas, mapping spatial frequency and correlating with tumor grades.

RESULTS:
Of 881 patients with meningioma (median age: 57 years, 68.8% female), 589 were WHO grade 1 (66.8%), 265 WHO grade 2 (30.1%), and 27 WHO grade 3 (3.1%) with a median tumor volume of 14.6 cm3. After molecular reclassification, 585 were IG-1 (66.4%), 160 IG-2 (18.2%), and 136 IG-3 (15.4%). Benign tumors were concentrated in and around the midline anterior skull base while malignant meningiomas were enriched in the falcine/parasagittal region and the sphenoid wing, similar to the distribution when stratified by chromosome 1p loss. Meningiomas exhibited sharper spatial clustering when stratified by the molecular IG than by WHO grade. WHO grade 2 meningiomas divided equally across IG 1-3, with corresponding partition of spatial distribution in the midline anterior skull base (in WHO grade 2, IG-1) and falcine/parasagittal and sphenoid regions (WHO grade 2, IG-3). Meningioma volumes significantly varied across age, sex, and WHO/IG grades.

CONCLUSION:
We demonstrate the utility of voxel-based lesion mapping for intracranial tumors, characterizing distinct meningioma distribution patterns across histopathological and molecularly defined grades. Molecular grading associated with sharper tumor spatial clusters, supporting a phenotype-genotype association in meningiomas.
Analisis Faktor yang Mempengaruhi Tingkat Kecelakaan Lalu Lintas di Kabupaten Sikka
Authors: Putri Agnesia Sonia Yulian , Aswim Danar , Natsir Rodja Abdul 
Published: August 2024

Penelitian ini analisis faktor yang mempengaruhi tingkat kecelakaan lalu lintas di Kabupaten Sikka. Penelitian ini bertujuan untuk mengetahui apa faktor yang mempengaruhi tingkat kecelakaan lalu lintas di Kabupaten Sikka dan bagaimana upaya penegakkan hukum yang dilakukan Polres Sikka. Metode penelitian yang digunakan adalah metode deskriptif Kuantitatif. Jenis data Yang digunakan adalah data primer dan data sekunder. Data primer diperoleh dari Observasi, wawancara sedangkan data sekunder diperoleh dari studi dokumen. Teknik analisis Data yaitu dengan cara pengumpulan data dianalisis berdasarkan rumusan masalah yang hendak diketahui faktor penyebab dan solusi yang dapat dipergunakan. Berdasarkan hasil analisis, faktor penyebab yang memicu terjadinya kecelakaan Lalu lintas adalah faktor manusia, faktor kendaraan dan faktor jalan. Faktor penyebab Yang paling dominan adalah manusia.selain faktor manusia dan Faktor kendaraan, faktor jalan juga menjadi pemicu terjadinya kecelakaan lalu lintas Karena dari hasil observasi yang dilakukan terdapat jalan yang kurang penerangan jalan, jalan berlubang dan jalan berkelok.
Dampak Media Sosial terhadap Pelanggaran Nilai-Nilai Karakter Siswa di MTs Muhammadiyah Wuring
Authors: Ahmadi Ahmadi , Natsir Rodja Abdul , Wahab Muhammad Ikhsan 
Published: August 2024

Penelitian ini bertujuan untuk untuk mengetahui apa saja dampak dari media sosial terhadap pelanggaran nilai-nilai karakter siswa dan untuk mengetahui bagaimana upaya mengatasi siswa yang melanggar nilai-nilai karakter. penelitian ini menggunakan metode kualitatif. Penelitian ini menggunakan dua sumber data yaitu data primer: kepala sekolah, guru dan siswa, data sekunder: data yang diperoleh dari jurnal dan artikel. Berdasarkan dari hasil penelitian terhadap dampak media sosial terhadap pelanggaran nilai-nilai karakter siswa di MTS Muhammadiyah Wuring maka dapat disimpulkan bahwa dampak media sosial terhadap pelanggaran nilai-nilai karakter siswa, lebih banyak terlihat dampak negatif seperti siswa kurang dalam belajar, lebih banyak memainkan HP daripada membuka buku. Apalagi saat ini sistem dimana rata-rata siswa memang memiliki HP. Siswa juga kurang peduli terhadap lingkungan, tidak melihat kondisi lingkungan terkadang terbiasa berkumpul membahas hal-hal viral yang ada di media sosial. Bahkan berkumpul untuk membuat video bersama dan berjoget bersama. Siswa sekolah masih sangat rentan terpengaruh oleh lingkungan, belum lagi saat untuk siswa sebelum mampu membedakan yang mana yang baik dan yang buruk, sedangkan di dalam media sosial tentunya memiliki dampak positif dan negatif. Para siswa sekarang lebih banyak menggunakan handphone dan banyak membicarakan hal-hal yang disebut viral di media sosial daripada membahas tentang pembelajaran. Siswa yang menggunakan media sosial sejak lama dengan tujuan hanya untuk mengisi waktu luang, bahkan buat hiburan bagi mereka apabila bosan setelah belajar. Bahkan media tidak pernah dijadikan sebagai media belajar, meskipun ada konten edukasi, mereka hanya melewatkannya saja, tidak mengikuti. Hal ini tentunya menjadi hal yang sangat mengkhawatirkan bagi masa depan anak, selain digunakan sebagai sarana hiburan tetapi banyak sekali unggahan-unggahan yang merusak nilai-nilai karakter dan perilaku anak. Hal ini tentunya diperlukan pengawasan bagi orang tua terhadap anaknya dalam penggunaan media sosial, agar karakter dalam diri anak terjaga bermoral, beretika serta berakhlak mulia.
Penggunaan Alat Peraga Keranjang Angka untuk Meningkatkan Hasil Belajar Peserta Didik Kelas II SDI Waioti
Authors: Sanyati Ine , Wahyuningsih Wahyuningsih , Wahyuningsih Wahyuningsih , Rahmawati Tanti Diyah , Rahmawati Tanti Diyah 
Published: August 2024

Matematika merupakan pelajaran yang sangat penting. Matematika adalah bidang penelitian yang abstrak, dan objek pembelajaran matematika adalah benda-benda yang abstrak. Oleh sebab itu peserta didik perlu membayangkan konsep tersebut. Hal ini menunjukkan bahwa objek matematika sulit untuk diamati dan dipahami melalui panca indera. Sebagian peserta didik yang masih menganggap pelajaran matematika sebagai pelajaran yang sulit, khususnya pada tingkat sekolah dasar karena pada tingkat ini taraf berpikir mereka masih pada tahap operasional konkret, dimana kemampuan yang ditunjukkan pada tahap ini adalah kemampuan proses berpikir untuk mengoperasikan kaidah-kaidah logika yang masih tetap terbatas pada objek yang nyata. Dengan demikian untuk mempelajari matematika yang bersifat abstrak, media yang digunakan agar peserta didik dapat memahami objek tersebut adalah media alat peraga. Alat peraga tersebut digunakan dalam pembelajaran matematika untuk mengurangi keabstrakan materi matematika saat mempelajari objek matematika. Tujuan dalam penelitian ini yaitu untuk mengetahui bagaimana Penggunaan alat peraga keranjang angka dalam menentukan nilai tempat untuk meningkatkan hasil belajar peserta didik. Penelitian ini dilakukan di SDI Waioti. Metode penelitian yang digunakan adalah penelitian Tindakan kelas. Hasil penelitian ini menunjukkan bahwa penggunaan alat peraga keranjang angka dalam menentukan nilai tempat dapat meningkatkan hasil belajar peserta didik dengan rata-rata siklus 1 sebesar 64,71 menjadi 90,59 disiklus ke II.
Determining the Extent of damage in Snapped Southern Yellow Pine Trees with Acoustic Testing
Authors: Smidt Mathew F. , Musah Munkaila , Mitchell Dana , Cannon Jeffery B. , Via Brian K. 
Published: August 2024

Abstract
Salvage of downed timber following a windstorm allows recovery of management options for landowners and wood products for industry. Because wood volumes are large and logging, transportation, mill storage, and processing capacities are limited, avoiding the selection of logs with damage can conserve those resources. Visual damage indicators are typically used to select and differentiate products, but damaged logs are still delivered to mills. Following experimental tree winching in 2021 and a tornado in 2023, we assessed lengths of broken trees with a Fakopp microsecond timer. Using a recognized defect limit (10% deviation from the maximum acoustic velocity) about 80 percent of volume in broken tops could be recovered. Standard rules of thumb applied from the end of visible damage resulted in the recovery of about 50 percent of the volume with a relatively low defect rate (<10%). Applying bucking rules developed from acoustic measurements based on distance from snap might be easier to apply and increase recovery rates to over 70 percent of broken top volume.
A study of the effects of four reading styles on college students’ mental health and quality of life based on positive psychology-A first-of-its-kind study
Authors: Liu Yamei 
Published: August 2024

Background
The increase in mental health problems among college students has become a global challenge, with anxiety and depression in particular becoming increasingly prevalent. Positive psychology has gained attention as an important psychological intervention that emphasizes improving mental health by promoting positive emotions and mindfulness. However, with the diversity of reading styles, however, there is a lack of systematic research on these effects. Therefore, this study aims to explore the specific effects of different reading styles on college students’ mental health and quality of life based on positive psychology, with the aim of providing more effective interventions and recommendations for improving college students’ mental health.

Methods
This study used a two-round questionnaire to select students with mental health problems and divided them into four experimental groups with a control group. The study was conducted by distributing questionnaires and experimental interventions, and a total of 2860 valid questionnaires were collected. The study used the Self-Assessment Scale for Anxiety (SAS) and the Self-Depression Scale (SDS) to assess the participants’ anxiety and depression levels. In addition, the study used the Physical Composite Score (PCS) and the Mental Composite Score (MCS) to assess the participants’ quality of life. SPSS 26.0 was used for data statistics and repeated measures ANOVA was used.

Results
Paper text reading and audio reading methods were effective in reducing anxiety levels and improving sleep quality. However, the electronic text reading approach was less effective compared to paper text reading and audio reading, and the video reading approach was not effective in improving depression. In addition, the positive psychology literature reading intervention showed significant improvements in college students’ quality of life scores.

Conclusion
The results of this study suggest that paper text reading and audio reading modalities have a positive impact on the mental health and quality of life of college students, while e-text reading and video reading modalities are less effective. These findings provide suggestions for college students to choose appropriate reading styles and further demonstrate the effectiveness of positive psychology reading on mental health. These results have important academic and practical implications for promoting mental health and improving quality of life among college students.
Cross-sectional analysis of national testosterone prescribing through prescription drug monitoring programs, 2018–2022
Authors: Selinger Scott , Thallapureddy Aneesh 
Published: August 2024

Background
For two decades preceding the COVID-19 pandemic, testosterone therapy (TT) became more prevalent in the US. Given the forced shift in practice patterns and healthcare accessibility during the pandemic, it was unclear how TT utilization would change.

Objective
To assess the change in testosterone prescriptions nationally.

Design
Cross-sectional study.

Data sources
State prescription drug monitoring program data between 2018 and 2022.

Participants
All individuals filling testosterone prescriptions in participating states.

Measurements
Unique people filling testosterone prescriptions annually, demographic information on gender and age as available.

Results
In 2022 there was a 27% relative increase of subjects treated with TT (+439,659 cases compared with 2018). The increase was more evident in the pandemic period with a rise in prevalence most notable for people 45–54 (114,114 people, 35% increase) and 35–44 (97,263 people, 58% increase). All regions except the Midwest increased the total population treated, led by the South (52%) followed by the West (28%) and Northeast (23%). Available data indicated men accounted for most patients treated in all age groups except under 24 years.

Limitations
Study population limited to those in participating states with no diagnostic information and limited demographics available.

Conclusion
Between 2018 and 2022, and primarily after the start of the pandemic in 2020, nationally there was a substantial increase in the number of people using TT. The largest increases occurred in a younger demographic, primarily men, than have previously been reported or studied. These results echo other findings showing increased use of controlled substances during the pandemic period and warrant further study regarding the factors behind this rise.