bluuebunny/crossref_metadata_2025_split huggingface dataset:
In vivo efficacy of fresh versus frozen osteochondral allografts in the goat at 6 months is associated with PRG4 secretion
Authors: Pallante‐Kichura Andrea L. , Chen Albert C. , Temple‐Wong Michele M. , Bugbee William D. , Sah Robert L. 
Published: January 2013

AbstractThe long‐term efficacy of osteochondral allografts is due to the presence of viable chondrocytes within graft cartilage. Chondrocytes in osteochondral allografts, especially those at the articular surface that normally produce the lubricant proteoglycan‐4 (PRG4), are susceptible to storage‐associated death. The hypothesis of this study was that the loss of chondrocytes within osteochondral grafts leads to decreased PRG4 secretion, after graft storage and subsequent implant. The objectives were to determine the effect of osteochondral allograft treatment (FROZEN vs. FRESH) on secretion of functional PRG4 after (i) storage, and (ii) 6 months in vivo in adult goats. FROZEN allograft storage reduced PRG4 secretion from cartilage by ∼85% compared to FRESH allograft storage. After 6 months in vivo, the PRG4‐secreting function of osteochondral allografts was diminished with prior FROZEN storage by ∼81% versus FRESH allografts and by ∼84% versus non‐operated control cartilage. Concomitantly, cellularity at the articular surface in FROZEN allografts was ∼96% lower than FRESH allografts and non‐operated cartilage. Thus, the PRG4‐secreting function of allografts appears to be maintained in vivo based on its state after storage. PRG4 secretion may be not only a useful marker of allograft performance, but also a biological process protecting the articular surface of grafts following cartilage repair. © 2013 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 31: 880–886, 2013
The role of sinus surgery in children
Authors: Makary Chadi A. , Ramadan Hassan H. 
Published: January 2013

Objectives/HypothesisTo critically review the current literature discussing the outcome of endoscopic sinus surgery (ESS) in children with chronic rhinosinusitis (CRS).Study DesignLiterature review.MethodsPubMed database and the Cochrane Library were searched. The PubMed search included all English‐language literature published between January 1990 and July 2012 discussing the role of ESS in children with CRS. Studies that included patients with cystic fibrosis, primary immunodeficiency disorders, or ciliary dysmotility disorders were excluded.ResultsOf the 507 articles retrieved from the primary research strategy, 11 studies were included for further discussion. There were no randomized controlled studies. The rate of success of pediatric ESS ranged from 82% to 100% in selected patients. Children undergoing ESS for CRS usually have more severe disease compared to those who get medical treatment or adenoidectomy. The extracted rate of complication was 1.4%, with no cases of cerebrospinal fluid leak or major orbital injury such as hematoma or blindness reported.ConclusionsESS offers a surgical alternative in the treatment of CRS in children with an excellent safety profile. There remains a need for higher level studies addressing the indications of ESS in children.Level of Evidence2a
Soil Properties and Maize Growth in Saline and Nonsaline Soils using Cassava‐Industrial Waste Compost and Vermicompost with or Without Earthworms
Authors: Oo A. N. , Iwai C. B. , Saenjan P. 
Published: January 2013

AbstractThe aim of this study was to investigate the effectiveness of compost and vermicompost as soil conditioners in alleviating salt‐affected soils and increasing maize productivity. A greenhouse trial, consisting of seven soil amendment treatments in a completely randomized design with three replications, was carried out at Khon Kaen University, Thailand, during the rainy season of 2011. Plant height and total dry matter of maize increased in treatments with compost and vermicompost application when compared with the control (no fertilizer) in two types of soils (saline and nonsaline) during the growing season. Soil pH and electrical conductivity in saturation paste extracts were decreased by compost and vermicompost amendments with or without earthworms when compared with unamended treatments in the saline soil. Compost and vermicompost amendments improved cation exchange capacity, soil organic carbon, total nitrogen and extractable phosphorus in both soils. These amendments also increased exchangeable K+, Ca2+ and Mg2+ while decreasing exchangeable Na+ in the saline soil, which suggested that Ca2+ was exchanged for Na+, exchangeable Na+, then leached out, and soil salinity reduced as a result. Soil microbial activities including microbial C and N and basal soil respiration were improved by the application of compost and vermicompost amendments with or without earthworms when compared with the control in both soils. This experiment showed that the compost and vermicompost were effective in alleviating salinity and improving crop growth. Copyright © 2013 John Wiley & Sons, Ltd.
Slotline‐fed ultracompact antenna for wide band applications
Authors: Nair Sreejith M. , Shameena V. A. , Sreenath S. , Mohanan P. 
Published: January 2013

AbstractA compact, wide‐band slotline‐fed uniplanar antenna is presented. The antenna offers a wide bandwidth from 3.8 to 10.2 GHz with a directional radiation pattern in the entire operating band. Also the antenna offers an average gain of 5 dBi in the entire band with an average efficiency of 85%. The antenna possesses an overall dimension of 21.9 × 8.8 × 1.6 mm3 when fabricated on substrate of dielectric constant 4.4 and thickness 1.6 mm. © 2012 Wiley Periodicals, Inc. Microwave Opt Technol Lett 54:526–529, 2013; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.27355
Design and validation of low‐pass filter using microstrip stub and defected ground structure
Authors: Tamasi Moyra , Santanu Das , Susanta Parui 
Published: January 2013

AbstractIn this article, a compact microstrip low‐pass filter using conventional elliptical headed dumbbell‐shaped defected ground structure (DGS) is presented.The proposed structure with main dimension parameters has been analyzed as a design guide, which can be used to fabricate the filter in future. The H‐shape open stub increases the equivalent parallel capacitance to improve the out‐band suppression. The proposed LPF shows low cut‐off frequency response, low insertion loss, sharp transition, and fairly good rejection in stop band. For the five‐array DGS filter, including stubs provides the rejection in stop band from 2.8 GHz to higher frequencies. DGSs have shown increasing potential for implementation in different applications: microwave integrated circuit (MIC), monolithic microwave integrated circuit (MMIC), and radio frequency integrated circuit (RFIC). They provide sharp, distinct electromagnetic band‐gap, and high slow wave factor, which lead to smaller size circuits and takes lots of engineering challenges. © 2012 Wiley Periodicals, Inc. Microwave Opt Technol Lett 55:571–573, 2013; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.27361
Secure dual‐chip contactless card with an integrated complementary touch switch
Authors: Shin B. H. , Yum J. W. , Kim S. H. , Lee J. Y. , Jang J. H. 
Published: January 2013

AbstractA complementary operating dual‐chip contactless card is designed by incorporating an integrated touch switch to avoid potential identity theft.The designed contactless card contains two microchips for a credit card and a transport card. Users can select which card will be used by touching the integrated switch, which is composed of parallel copper plates. By touching the integrated switch with a finger, the impedance of the switch is changed and the power transferred to the microchip is also changed. When the power transferred to the microchip is higher than the threshold power, the microchip is activated. In the normal state, i.e., the untouched state, only the microchip for the transport card is activated. When the switch is touched by a finger, the microchip for the transport card is deactivated and the microchip for the credit card is activated. By incorporating a simple touch switch, the smart card can be under the user's control so that unwanted identity theft or unauthorized credit card charges can be avoided. © 2012 Wiley Periodicals, Inc. Microwave Opt Technol Lett 54:529–533, 2013; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.27362
A compact ultrawideband antenna with two band‐notches
Authors: Zhai Huiqing , Ou Jinxia , Li Tong , Li Guihong , Li Long , Liang Changhong 
Published: January 2013

AbstractA compact ultrawideband (UWB) antenna with two band‐notched characteristics is presented and investigated in this article.Two conformal U type slots are etched on the patch to generate two notched bands at 3.5 and 5.2–5.8 GHz, which contribute good rejection of interference with WiMAX (3.5 GHz) and wireless local area network (5.2–5.8 GHz), each of which can be controlled independently. The presented antenna can provide an UWB bandwidth with expected notched band, and it has omnidirectional radiation pattern and stable gain at working frequencies according to simulation and measurement results. © 2012 Wiley Periodicals, Inc. Microwave Opt Technol Lett 55:583–586, 2013; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.27369
Polarization reconfigurable microstrip patch antenna
Authors: Han Tuan‐Yung , Jiashih Shih Chuang , Row Jeen‐Sheen 
Published: January 2013

AbstractThe performances of a quasilumped coupler with a pair of capacitors are first described. By varying the capacitance value of the capacitors, the coupler can operate at three different modes, including uncoupled‐line mode, quadrature hybrid mode, and T‐junction power divider mode. Based on the coupler design, a microstrip antenna with switchable polarization is developed and implemented. Experimental results demonstrate that the reconfigurable antenna can provide two linear polarizations and one circular polarization at one frequency. In addition, the antenna operating at each polarization state has good impedance matching and broadside radiation with low cross polarization. © 2012 Wiley Periodicals, Inc. Microwave Opt Technol Lett 54:471–474, 2013; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.27374
A novel design of reconfigurable small monopole antenna with switchable band notch and multi‐resonance functions for UWB applications
Authors: Ojaroudi Nasser , Ojaroudi Mohammad 
Published: January 2013

AbstractA novel reconfigurable square monopole antenna with switchable band‐notch and multiresonance performances is designed and manufactured.In the proposed structure, by cutting an inverted Γ‐shaped slit with variable dimension on the ground plane, new additional resonance is excited and hence much wider impedance bandwidth can be produced, especially at the higher band. Additionally, to generate multiresonance characteristics, we use an inverted U‐ring shaped slot, in the ground plane. To achieve reconfigurable function, we use a pin diode across the inverted U‐ring slot in the ground plane. When this pin diode is biased, the inverted U‐ring slot has converted to a rectangular slot with an E‐shaped strip protruded inside the slot, and also by creating this new structure, band notched performance is generated. The designed antenna has a small size of 12 × 18 mm2 while showing the radiation performance in the frequency band of 3.02 to over 12.97 GHz with a band rejection performance in the frequency band of 5.03–5.98 GHz. Simulated and experimental results obtained for this antenna with a reconfigurable frequency function in the range of 5 GHz–6 GHz show that it exhibits good radiation behavior within the UWB frequency range. © 2012 Wiley Periodicals, Inc. Microwave Opt Technol Lett 55:652–656, 2013; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.27376
Very simple synthesis formulas for microcoplanar striplines
Authors: Yildiz C. , Kisioglu H. 
Published: January 2013

AbstractAccurate and very simple synthesis formulas for the microcoplanar strip (MCS) lines are presented. They are very useful for microwave engineers to easily and accurately compute the physical dimension of MCS lines. The coefficients in the synthesis formulas are determined with the use of artificial bee colony algorithm. The results of the synthesis formulas are compared with the results of respective quasi‐static analysis, other synthesis formulas, and experimental works available in the literature to show the validation of synthesis formulas presented in this article. The average percentage error is calculated 3.07% for 864 MCS line samples having different electrical parameters and physical dimensions. © 2012 Wiley Periodicals, Inc. Microwave Opt Technol Lett 54:615–619, 2013; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.27377
Novel wire‐bond free asymmetrical power divider for coplanar waveguide
Authors: León Germán , Herrán Luis F. , Heras Fernando Las 
Published: January 2013

AbstractThe design and the experimental result of an asymmetrical power divider based on three resonators in coplanar waveguide (CPW) technology are presented.In this work, resonators coupling do not excite unwanted modes in CPW. This characteristic can be used to design power dividers that do not need air‐bridges. The proximity of the resonators will determinate the coupling of the divider as well as the symmetrical or asymmetrical behavior of the element. This novel design has been measured and good power transfer is found in the bandpass. © 2012 Wiley Periodicals, Inc. Microwave Opt Technol Lett 55:629–632, 2013; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.27388
Novel low‐profile foam dielectric over‐the‐shoulder antenna based on coupled patches technique
Authors: Svanda Milan , Polivka Milan , Hudec Premysl 
Published: January 2013

AbstractThe article presents a novel wearable antenna composed of two coupled patches excited by an overlapping folded dipole. In spite of being operated in a relatively low frequency band 380 ÷ 390 MHz, the antenna shows a very low profile and other dimensions are acceptable as well. Besides a very low absorption of the radiated RF power by any nearby human body, it also ensures a very good immunity against influence on antenna parameters. In comparison to commonly used simple conformal monopole antennas, the presented solution provides a double‐side radiation pattern and a substantially higher gain. The antenna can be manufactured using very light and twistable foam dielectric and conductive fabric, and can be worn as a strap placed over the shoulder. It is intended to be used together with personal radio communication transceivers operated in the given frequency band. © 2012 Wiley Periodicals, Inc. Microwave Opt Technol Lett 55:593–597, 2013; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.27389
Design of an ultrawideband UHF embedded annular slot antenna
Authors: Zhu Yong Zhong 
Published: January 2013

AbstractA novel ultrawideband annular slot antenna for ultrahigh‐frequency airborne communication applications is presented. This antenna is composed of concave cylinder, four shorting inductive posts, a top plate, and backed cavity, and achieves a wide impedance bandwidth from 225 to 400 MHz. Measurements show that the proposed structure can get omnidirectional radiation pattern, and can be used in airborne applications as flush‐mounted alternatives to monopole blade antenna. © 2012 Wiley Periodicals, Inc. Microwave Opt Technol Lett 55:680–682, 2013; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.27400
Broadband three‐section symmetrical directional couplers with reduced coupling coefficient requirements
Authors: Staszek Kamil , Wincza Krzysztof , Gruszczynski Slawomir 
Published: January 2013

AbstractA new class of broadband symmetrical directional couplers has been investigated. The proposed couplers consist of three coupled‐line sections with the middle coupled‐line section connected between two identical coupled‐line sections in such a way that the coupled and transmission ports of the resulting three‐section directional coupler are exchanged in comparison to the well‐known three‐section symmetrical directional coupler. By choosing coupling coefficients and electrical lengths it is possible to achieve an equal‐ripple coupling characteristic. Theoretical analysis has been performed and the properties of the proposed directional couplers are compared to the well‐known multisection couplers. The presented theoretical analysis has been verified by the design. © 2012 Wiley Periodicals, Inc. Microwave Opt Technol Lett 55:639–645, 2013; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.27401
Epigenetic regulation of the X‐linked tumour suppressors BEX1 and LDOC1 in oral squamous cell carcinoma
Authors: Lee Chia‐Huei , Wong Thian‐Sze , Chan Jimmy Yu‐Wai , Lu Shao‐Chun , Lin Pinpin , Cheng Ann‐Joy , Chen Yin‐Ju , Chang Jeffrey Shu‐Ming , Hsiao Shu‐Huei , Leu Yu‐Wei , Li Chuan‐i , Hsiao Jenn‐Ren , Chang Jang‐Yang 
Published: January 2013

AbstractThe strong associations between oral squamous cell carcinoma (OSCC) and dietary habits such as alcohol consumption (A), betel quid chewing (B) and cigarette smoking (C) and its predominance in men have been well documented; however, systemic analysis of OSCC is limited. Our study applied high‐throughput screening methods to identify causative epigenetic targets in a cohort of men with ABC‐associated OSCC. We identified BEX1 and LDOC1 as two epigenetically silenced X‐linked tumour suppressors and demonstrated a functional link between the transcription of BEX1 and LDOC1 and promoter hypermethylation. Methylation of the BEX1 and LDOC1 promoters was associated significantly (p < 0.0001) with OSCC and were detected in 75% (42/56) and 89% (50/56) of the samples, respectively. We observed concordant increases in the methylation of both genes in 71% (40/56) of the tumours, and potent in vitro and in vivo growth inhibitory effects in OSCC cells ectopically expressing BEX1 and/or LDOC1. Restored expression of BEX1 and LDOC1 suppressed the nuclear factor‐κB (NF‐κB) signalling pathway, which is the most frequently hyperactivated signalling pathway in OSCC. This suppression might result from decreased p50 and p65 expression. These findings suggest that silencing of BEX1 and LDOC1 by promoter hypermethylation might represent a critical event in the molecular pathogenesis of OSCC and account for the oncogenic effects of ABC exposure and the male predominance of OSCC occurrence. Microarray data are available in the Gene Expression Omnibus (GEO; http://www.ncbi.nlm.nih.gov/geo/) Copyright © 2013 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.
Rapid detection of aneuploidies on a benchtop sequencing platform
Authors: Xie Weiwei , Tan Yueqiu , Li Xuchao , Lin Ge , Jiang Hui , Chen Fang , Zhang Chunlei , Gong Fei , Pan Xiaoyu , Chen Shengpei , Lu Guangxiu , Wang Wei , Zhang Xiuqing 
Published: January 2013

ABSTRACTObjectiveTo report a novel method of rapidly detecting fetal aneuploidies for spontaneous abortion using ultra‐low whole genome sequencing data on a benchtop sequencing platform.MethodFetal chorionic villus samples were collected from 40 cases of spontaneous abortion with 22 different types of aneuploidy. Genomic DNA of each sample was extracted and sequenced on Illumina MiSeq platform. Unique reads of different read lengths were generated and analyzed using a z‐score test.ResultsThe entire test was finished in 48 hours. An average of 102 k unique reads was obtained for each sample, and all 40 different aneuploidy samples were correctly identified with a z‐score of ≥3 or ≤ ‐3. No false positives or false negatives were observed. Further analysis demonstrated that read length and sequencing type (Paired‐end or Single‐end) significantly affects the efficiency of sex chromosomal aneuploidy detection. Paired‐end 50 bp reads displayed the highest mapping rate and is recommended for future large‐scale clinical settings.ConclusionUltra‐low whole genome sequencing can rapidly detect aneuploidy of chromosomes in spontaneous abortion samples in less than 48 hours and therefore can serve as an alternative option to current aneuploidy detection methods for aborted tissues. © 2013 John Wiley & Sons, Ltd.
In silico study of human aquaporin AQP11 and AQP12 channels
Authors: Calvanese Luisa , Pellegrini‐Calace Marialuisa , Oliva Romina 
Published: January 2013

AbstractAQP11 and AQP12 are the most distantly related paralogs of the aquaporin family in human. They share indeed a low sequence similarity with other aquaporins and exhibit a modified N‐terminal NPA signature motif. Furthermore, they have an anomalous subcellular localization. The AQP11 and AQP12 biological role remains to be fully clarified and their ability to allow transport of water is still debated. We have built accurate 3D‐models for AQP11 and AQP12 and comprehensively compared their sequence and structure to other known aquaporins. In order to investigate whether they appear compatible or not with water permeability, we especially focused on the amino acid composition and electrostatics of their channels, keeping the structure of the low‐water efficiency AQP0 as a reference system. Our analysis points out a possible alternative ar/R site and shows that these aquaporins feature unique residues at key pore‐lining positions that make the shape, composition and electrostatics of their channel peculiar. Such residues can represent pivotal hints to study and explain the AQP11 and AQP12 biological and molecular function.
Improved performance of organic solar cells by growth optimization of MoO3/CuI double‐anode buffer
Authors: Cattin L. , Bernède J. C. , Lare Y. , Dabos‐Seignon S. , Stephant N. , Morsli M. , Zamora P. P. , Diaz F. R. , del Valle M. A. 
Published: January 2013

AbstractWe investigated the effect of a CuI anode buffer layer (ABL) on the molecular orientation of the copper phthalocyanine (CuPc) in organic photovoltaic cells (OPV cells), and we compare it to the effect of MoO3 buffer layer. While, in the presence of CuI, the CuPc molecules lie down parallel to the substrate, they stand up perpendicular in the case of MoO3. We show that the optical absorption, the morphology, and the J–V characteristics of the OPV cells depends strongly on the orientation of the CuPc molecules. The improvement of the OPV cells performance is related to the property modifications induced by the change in molecule orientation. We show that the improvement of the OPV cell performance through the templating effect of CuI depends strongly on the deposition rate of the CuI, because the CuI thin‐film morphology depends on this deposition rate. In this context, we show that the use of a double‐ABL MoO3/CuI leads to a significant improvement of the cell performance. These results are discussed on the basis of the dual function of MoO3 and CuI. While both of them reduce the hole‐injection barrier, CuI improves the CuPc film absorbance through specific molecular order and MoO3 prevents the OPV cells from leakage‐path formation.