bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of memory effects in multiblock copolymers and covalently crosslinked multiphase polymer networks composed of the same types of oligoester segments and urethane linker
Authors: Wang Li , Nöchel Ulrich , Behl Marc , Kratz Karl , Lendlein Andreas 
Published: December 2013

ABSTRACTPhase-segregated multiblock copolymers (MBC) as well as covalently crosslinked multiphase polymer networks, which are composed of crystallizable oligo(ε-caprolactone) (OCL) and oligo(ω-pentadecalactone) (OPDL) segments have been recently introduced as degradable polymer systems exhibiting various memory effects. Both types of copolyesterurethane networks can be synthesized via co-condensation of the respective hydroxytelechelic oligomers and 2,2(4),4-trimethyl-hexamethylene diisocyanate (TMDI) as aliphatic linker.In this work the dual-shape properties as well as the temperature-memory capability of thermoplastics and covalently crosslinked copolyesterurethanes containing OCL and OPDL domains are explored. Both copolyesterurethane networks exhibited excellent dual-shape properties with high shape fixity ratios Rf ≥ 93% and shape recovery ratios in the range of 92% to 100% determined in the 2nd and 3rd test cycle, whereby the dual-shape performance was substantially improved when covalent crosslinks are present in the copolymer.A pronounced temperature-memory effect was achieved for thermoplastic as well as crosslinked copolyesterurethanes. Hereby, the switching temperature Tsw could be adjusted via the variation of the applied deformation temperature Tdeform in the range from 32 °C to 53 °C for MBC and in the range from 29 °C to 78 °C for multiphase polymer networks.
Decay of γ-H2AX foci correlates with potentially lethal damage repair and P53 status in human colorectal carcinoma cells
Authors: Oorschot Bregje , Oei Arlene , Nuijens Anna , Rodermond Hans , Hoeben Ron , Stap Jan , Stalpers Lukas , Franken Nicolaas 
Published: December 2013

AbstractThe influence of p53 status on potentially lethal damage repair (PLDR) and DNA double-strand break (DSB) repair was studied in two isogenic human colorectal carcinoma cell lines: RKO (p53 wild-type) and RC10.1 (p53 null). They were treated with different doses of ionizing radiation, and survival and the induction of DNA-DSB were studied. PLDR was determined by using clonogenic assays and then comparing the survival of cells plated immediately with the survival of cells plated 24 h after irradiation. Doses varied from 0 to 8 Gy. Survival curves were analyzed using the linear-quadratic formula: S(D)/S(0) = exp-(αD+βD2). The γ-H2AX foci assay was used to study DNA DSB kinetics. Cells were irradiated with single doses of 0, 0.5, 1 and 2 Gy. Foci levels were studied in non-irradiated control cells and 30 min and 24 h after irradiation. Irradiation was performed with gamma rays from a 137Cs source, with a dose rate of 0.5 Gy/min. The RKO cells show higher survival rates after delayed plating than after immediate plating, while no such difference was found for the RC10.1 cells. Functional p53 seems to be a relevant characteristic regarding PLDR for cell survival. Decay of γ-H2AX foci after exposure to ionizing radiation is associated with DSB repair. More residual foci are observed in RC10.1 than in RKO, indicating that decay of γ-H2AX foci correlates with p53 functionality and PLDR in RKO cells.
Estudio experimental de los efectos de la meditación trascendental en la personalidad de los reclusos
Authors: Banchick C. Doris , Silva A. Iván 
Published: December 2013

Existe evidencia de que a través del método de Meditación Trascendental (M.T.) es posible obtener cambios especialmente en la fisiología de los individuos (R.K.Wallace).Todos estos cambios implican un estado fisiológico distinguible y que podemos definir como un estado hipometabólico, que provoca relajación profunda, pero en un estado mental de vigilia y alerta (R.K. Wallace, H. benson y A.F. Wilson)También se lograría un estado de mayor estabilidad del Sistema nervioso Auton+omico (d.W. Orme-Johnson)
Desarrollo, participación y psicología comunitaria
Authors: Rozas Germán 
Published: December 2013

El estilo urbano industrial ha demostrado su calidad de concentrador de la riqueza, excluyente, generador de grandes desigualdades sociales. Más aún como plantea el enfoque histórico estructural problemas como: el dualismo, el extraversión, la desarticulación, el desequilibrio, la inestabilidad, la dependencia; son consecuencias graves que dejan secuelas profundas en nuestras sociedades latinoamericanas (Bouviers, 1989).Por otro lado desde el punto de vista psicológico y cultural el atropello a las tradiciones, a los esquemas ancestrales de conocer el trabajo, a los mecanismos religiosos-políticos de control social, a los sistemas integrados de salud mental con lo político y social etc. producen y han producido una destrucción de nuestras comunidades, especialmente las más autóctonas, si es que se puede hablar de tales comunidades (Rozas, 1989),
Modelo de Meta-Redes Intersectoriales en Psicología Comunitaria
Authors: Rozas O. Germán , Sapiains Rodolfo 
Published: December 2013

En el contexto de las políticas de descentralización de nuestro país, se ha realizado la presente investigación, de carácter cualitativa, sobre los modelos de intersectorialidad utilizados en la VI Región. Dichos modelos se refieren a una metodología de intervención,con participación de varias instituciones representantes de diversos sectores,que busca obtener un mayor impacto en la solución de los problemas sociales, y enparticular en torno a la superación de la pobreza.Los resultados permiten develar la existencia de diez tipos de acción intersectorial,los cuales van desde una amplia participación institucional hasta una colaboraciónrestringida a una sola institución. Aparecen además formas de intervención conjuntasy otras sujetas a críticas dada su fuerte egocentrismo institucional.Finalmente fruto de los datos encontrados se propone un modelo de Meta-Redes Intersectorial que busca hacer coherente no sólo el accionar institucional conjunto sino una adecuada articulación con el gobierno regional.El presente trabajo se enmarca dentro de una investigación Fondecyt Nº 1000830 en el área de la Psicología Comunitaria.
Patología Informacional
Authors: Loma-Osorio Sebastián , Schramm Nadine , Santibañez-H. Guy 
Published: December 2013

Esta presentación está dedicada a mostrar aspectos de la patología informacional debidos al efecto que el exceso de información tiene sobre el organismo.Si un organismo  humano o animal  es obligado a asimilar una cantidad de información que satisface una fuerte motivación, sin disponer del tiempo necesario para procesarla, sufre un estado tensional (estrés), el cual produce una patología que Chananashwili denominó neurosis informacional. Esta alteración tiene su base fisiopatológica en el Síndrome General de Adaptación, descrito por Selye (1950).El progreso tecnológico, las exigencias laborales y las modernas condiciones de vida, han favorecido la falta de actividad, la necesidad de tomar importantes decisiones en períodos cortos de tiempo, lo cual conduce a situaciones de estrés de larga duración.Esto afecta a determinados sistemas funcionales, a la aparición de los así llamados síndromes psicosomáticos, intensas reacciones emocionales y síntomas como angustia, ansiedad y depresiones además de otros.Dada la importancia que ésta patología adquiere en la actualidad, hemos querido dar un cuadro sintético, tanto en el aspecto clínico como en el experimental y, al mismo tiempo, señalar su relación directa con la dinámica de los acontecimientos económico-sociales.
Psique, soma, institución. Una lectura de la psicopatología del trabajo
Authors: Durán Rojas Cristóbal 
Published: December 2013

En el presente artículo se exponen y discuten algunas consideraciones sobre las relaciones entre el trabajo y ciertos aspectos psíquicos, presentes en la obra del psicoanalista francés Christophe Dejours. Para trazar dicho recorrido se enfatizan aquellas expresiones sintomáticas de esta relación que estarían haciendo visible un sufrimiento experimentado por el sujeto al verse enfrentado a la tarea de su puesto de trabajo. Allí, se considera de manera central el complejo vínculo que se establece entre la institución del trabajo y las exigencias que, por su parte, impone el propio psiquismo.
Grafología Científica: La Muestra de Escritura como Test Psicológico Proyectivo
Authors: Rojas Weisser Tamara 
Published: December 2013

El siguiente artículo consiste en una reflexión sobre la fundamentación teórica de laGrafología, estableciendo que su objeto de estudio, la escritura, se constituye en unacto de proyección de la psique de quien escribe. Se propone la existencia de unFactor T a la base del proceso, una suerte de patrón constante y repetitivo que haceestable al acto escritural. Este factor T daría la base para considerar las fluctuaciones de la onda gráfica como reflejos de contenidos inconscientes, traducibles a una interpretación de rasgos profundos de personalidad. Por otra parte, también se revisa la metodología de análisis y los alcances clínicos de la técnica en orientación vocacional y profesional.
Lamination of polyethylene composite films by ultrasonic welding: Investigation of peel behavior and identification of optimum welding parameters
Authors: van Oordt Thomas , Barb Yannick , Zengerle Roland , von Stetten Felix 
Published: December 2013

AbstractThe lamination of different polyethylene (PE) composite films by ultrasonic welding to fabricate peelable seals that open at defined burst pressures is investigated. The sealing time, pressure, and amplitude were varied within the range of 100–400 ms, 50–250 kPa, and 12–24 µm, respectively. T‐peel tests and electron micrographs revealed four different peel regimes, depending on the parameter combination: (I) Interlaminar peeling at low‐peel strength with uniform peeling along a weakly bonded PE lamination layer; (II) transition tearing at intermediate peel strength showing areas of interlaminar peeling and translaminar tearing; (III) translaminar tearing at high‐peel strength showing tears through the entire film; and, (IV) undefined tearing at varying tear strength occurring when vibration effects during welding lead to insufficient contact of the films or high pressures lead to a displacement of PE. This study will allow the systematic adjustment of ultrasonic welding parameters for PE films. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2014, 131, 40291.
Maternal isolation during the first two postnatal weeks affects novelty‐induced responses and sensitivity to ethanol‐induced locomotor activity during infancy
Authors: Fernández Macarena , Fabio María Carolina , Nizhnikov Michael E , Spear Norman E. , Abate Paula , Pautassi Ricardo Marcos 
Published: December 2013

ABSTRACTAnimals exposed to chronic maternal separation (MS) exhibit enhanced ethanol self‐administration and greater hormonal and behavioral responsiveness to stress in adulthood. Whether the effects of MS are immediately evident in infancy or whether they appear only later on development is still an unanswered question This study tested sensitivity to ethanol's behavioral stimulating effects in infant rats that experienced MS from postnatal Day 1–14. MS infants exhibited significantly greater reactivity to the motor stimulating effects of 1.25 g/kg ethanol than control animals, yet greater motor suppression after 2.5 g/kg ethanol. Baseline level of response to novelty was altered in MS infants, in a nor‐binaltorphimine insensitive manner, that is, despite modified activity of the kappa‐opioid system. These results indicate that the consequences of chronic maternal isolation emerge early in ontogeny, affecting ethanol sensitivity in infancy. © 2013 Wiley Periodicals, Inc. Dev Psychobiol 56: 1070–1082, 2014.
Every which way—nanos gene regulation in echinoderms
Authors: Oulhen Nathalie , Wessel Gary M. 
Published: December 2013

SummaryNanos is an essential factor of germ line success in all animals tested. This gene encodes a Zn‐finger RNA‐binding protein that in complex with its partner pumilio binds to and changes the fate of several known transcripts. We summarize here the documented functions of Nanos in several key organisms, and then emphasize echinoderms as a working model for how nanos expression is regulated. Nanos presence outside of the target cells is often detrimental to the animal, and in sea urchins, nanos expression appears to be regulated at every step of transcription, and post‐transcriptional activity, making this gene product exciting, every which way. genesis 52:279–286. © 2013 Wiley Periodicals, Inc.
Hybrid nanocomposites based on POSS and networks of methacrylated camelina oil and various PEG derivatives
Authors: Balanuca Brindusa , Lungu Adriana , Hanganu Ana‐Maria , Stan Liane Raluca , Vasile Eugeniu , Iovu Horia 
Published: December 2013

Several photo‐curable hybrid systems based on methacrylate‐modified camelina oil (CO) were synthesized through a copolymerization reaction with hydrophilic dimethacrylated poly(ethylene glycol) macromonomers (PEG MW = 300, 550, and 750 g/mol). In a first step, the epoxidation and subsequently the methacrylation reactions of CO were performed and monitorized using 1H NMR and FTIR. Further, the polymerization reaction of the new synthesized oil‐based monomer under visible light was proved by FTIR. The chain length of methacrylate functionalized PEG was found to directly influence some key properties of the oil‐based networks. The curing performance of the systems was studied by GF measurements. Water uptake capacity tests and contact angle measurements were undertaken and it was found that the internal arrangement of components is strongly affecting the hydrophilicity of the materials. Furthermore, nanostructured polyhedral oligomeric silsesquioxane (POSS) compounds bearing one or eight methacrylated groups were selected in order to obtain innovative organic–inorganic nanocomposites. Mechanical and thermal properties were evaluated by compression tests, DMA, TGA, and also the morphology of the synthesized materials was investigated by SEM.Practical applications: Tailoring the copolymer composition and the reinforcing agent in the manufacturing process leads to a wide range of products with optimum properties suitable for use in a variety of industrial areas. Well‐defined oil‐derived systems with controllable compressive strength were prepared in this work covering the whole range, from a hard material (with short chain PEG) to a soft and flexible one (with long chain PEG).
Effects of macrophytes on the fate of mercury in aquatic systems
Authors: Cosio Claudia , Flück Rebecca , Regier Nicole , Slaveykova Vera I. 
Published: December 2013

Abstract

Vegetated and shallow areas such as wetlands and salt marshes, as well as freshwater lakes and rivers, have been identified as hotspots for Hg methylation. The presence of aquatic macrophytes, the predominant primary producers in shallow waters, plays an important but still poorly understood role in the fate of Hg in these environments. The present review focuses on the influences of macrophytes on Hg speciation and distribution in sediments, the rhizosphere, and the water column; on Hg transformation; and on Hg release to the environment, including transfer to the trophic web. Future research will require an improved understanding of the mechanisms and the factors controlling these aspects as well as a broader general view. Thus, the main gaps in knowledge are also discussed. Environ Toxicol Chem 2014;33:1225–1237. © 2014 SETAC
Strangling technique to treat large cervicofacial venous malformations: A preliminary report
Authors: Colletti Giacomo , Colombo Valeria , Mattassi Raul , Frigerio Alice 
Published: December 2013

ABSTRACTBackgroundSurgical removal of large cervicofacial venous malformations might be hampered by massive intraoperative bleeding. Moreover, these lesions often insinuate within normal surrounding tissue, making complete resection impossible without causing significant morbidity.MethodsTwo patients affected by facial venous malformations nonresponsive to sclerotherapy underwent surgery. Bleeding and critical branching of the facial nerve within the lesion prevented the surgeons from proceeding with the removal. The unresectable malformation was decompressed by means of a number of nonresorbable stitches from the surface of the lesion to the periosteum, tailoring a permanent pressure dressing.ResultsOutcomes at 12‐month follow‐up were stable, with good cosmetic results and satisfaction reported by both patients. No long‐term side effects related to the procedure were observed.ConclusionDecompression of large venous malformations by means of a strangling technique might represent a safe and effective procedure for those cases where a removal cannot be accomplished. © 2014 Wiley Periodicals, Inc. Head Neck, 36: E94–E98, 2014
Endoscope‐assisted transoral approach to parapharyngeal space tumors
Authors: Iseri Mete , Ozturk Murat , Kara Ahmet , Ucar Selcuk , Aydin Omer , Keskin Gurkan 
Published: December 2013

AbstractBackgroundParapharyngeal space (PPS) tumors are rare tumors for which the surgical management differs widely. The purpose of this study was to discuss the advantages and disadvantages of the endoscope‐assisted transoral approach over the traditional approaches.MethodsThis prospective study included 4 patients who were diagnosed with PPS tumors and treated with the endoscope‐assisted transoral approach.ResultsThe endoscope‐assisted transoral approach described here safely allowed for the resection of benign neoplasms with high surgical view to the parapharyngeal neurovascular structures. The average tumor size was 42 mm. Three patients had isolated PPS tumors, and 1 patient had a tumor originating from the deep lobe of the parotid gland. The postoperative histopathological diagnosis of the patients was pleomorphic adenoma for 3 of the patients, and marginal zone and follicular hyperplasia for the other.ConclusionThis technique provided less operative trauma, a more comfortable postoperative period, and, most importantly, increased operative exposure. © 2014 Wiley Periodicals, Inc. Head Neck 37: 243‐248, 2015
Pharmacokinetics of different formulations of oral azacitidine (CC‐486) and the effect of food and modified gastric pH on pharmacokinetics in subjects with hematologic malignancies
Authors: Laille Eric , Savona Michael R. , Scott Bart L. , Boyd Thomas E. , Dong Qian , Skikne Barry 
Published: December 2013

AbstractParenteral azacitidine improves overall survival in higher‐risk myelodysplastic syndromes. An oral azacitidine formulation would allow extended dosing schedules, potentially improving safety and/or efficacy. Two Phase 1 studies evaluated the pharmacokinetics (PK) of oral azacitidine in subjects with hematologic malignancies. Study 1 evaluated different oral formulations (immediate release tablet [IRT], enteric‐coated tablet, and capsule; N = 16). Study 2 assessed the effect of food (Part 1; N = 17) and gastric pH modulation with omeprazole (Part 2; N = 14) on oral azacitidine PK. Azacitidine plasma concentration–time profiles for IRT and capsule formulations were similar, with more rapid time to maximum plasma concentration (Tmax) than the enteric‐coated tablet. Study 2 evaluated only IRT formulations of oral azacitidine. Under fed condition, Tmax was delayed ∼1.5 hours but area under the concentration–time curve (AUC∞) and maximum plasma concentrations (Cmax) were comparable under fed and fasted conditions. Mean azacitidine AUC∞ and Cmax increased upon omeprazole co‐administration (18.3% and 13.2%, respectively, vs. oral azacitidine alone), but not to a clinically meaningful extent. High inter‐subject variability in AUC∞ and Cmax (%CV range 46.4–68.9%) was observed. Oral azacitidine is rapidly absorbed with little or no effect of food on PK parameters, and does not require dose adjustments when taking a proton‐pump inhibitor.
Appendiceal goblet cell carcinoid and mucinous neoplasms are closely associated tumors: Lessons from their coexistence in primary tumors and concurrence in peritoneal dissemination
Authors: Ng Denise , Falck Vincent , McConnell Yarrow J. , Mack Lloyd A. , Temple Walley J. , Gui Xianyong 
Published: December 2013

BackgroundGoblet cell carcinoid (GCC) and appendiceal mucinous neoplasms (AMNs) are considered as different appendiceal tumors. Coexistence of both tumors was occasionally noted. We further observed the concurrence in both primary tumors and their peritoneal dissemination, that is, peritoneal carcinomatosis (PC) including pseudomyxoma peritonei (PMP).MethodsReview of our 10‐year file identified two subgroups of cases with such concurrence. Group 1 is 14 cases of PC/PMP treated by surgical cytoreduction. Morphologic components of GCC, low‐grade mucinous neoplasm (LMN), mucinous adenocarcinoma (MCA), and non‐mucinous adenocarcinoma (NMCA) were identified separately in different organs/tissues. Group 2 is eight cases of localized primary tumors of appendix and ileocecal junction.ResultsIn Group 1, primary tumors (11 GCC, 1 GCC + LMN, 1 MCA, 1 NMCA) were identified in appendix (13) and in rectum (1). Further review identified mixed morphologic components in 7/12 GCC cases, including GCC + LMN (2), GCC + MCA (2), GCC + NMCA (1), and GCC + MCA + NMCA (2). Over peritoneal dissemination, GCC and/or other components were coexistent at different sites and in variable combinations. In Group 2, primary tumors were initially diagnosed as GCC (7) and MCA (1). Further review identified mixed components in all cases, including GCC + LMN (3), GCC + LMN + MCA (3), GCC + MCA + NMCA (2).ConclusionsGCC may present as a component mixed with AMNs and even with conventional adenocarcinoma in both primary tumors and metastatic lesions. AMN in any given single case may show a wide morphologic spectrum. GCC and AMN may share a common tumor stem cell with potential of multiple lineage differentiations. J. Surg. Oncol. 2014 109:548–555. © 2013 Wiley Periodicals, Inc.
Design of dual band‐notched planar inverted cone ring antenna for UWB communications
Authors: Thwin Su Sandar 
Published: December 2013

ABSTRACTA compact microstrip‐fed ultrawideband (UWB) symmetrical inverted cone ring monopole antenna with dual band‐notched characteristics for worldwide interoperability for microwave access (WiMAX) and wireless local area network (WLAN) is proposed. The proposed antenna which has the size of 23.6 × 40 mm2, is fabricated on a low‐cost FR4 substrate that has the relative permittivity (εr) of 4.4 and substrate thickness of 1.6 mm to operate in the UWB band (3.1–10.6 GHz) released by Federal Communications Commission in 2002. A pair of L‐shaped slots is etched symmetrically on the ground plane and L‐shaped strip is added at the side of the microstrip feed line to reject 3.5‐GHz WiMAX and 5.2/5.8‐GHz WLAN band. The measured bandwidth of VSWR ≤ 2 is from 2.4 to 11 GHz with the band‐notched of 3–4.2 GHz for WiMAX band and 4.9–6.1 GHz for WLAN band. Moreover, the proposed antenna exhibits omnidirectional radiation patterns with acceptable gain across the whole band. The prototype of the proposed antenna was fabricated and tested. The measured results agree well with the simulated ones. © 2014 Wiley Periodicals, Inc. Microwave Opt Technol Lett 56:284–287, 2014