bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analyzing the factors affecting coordination in engineer-to-order supply chain
Authors: Mello Mario Henrique , Strandhagen Jan Ola , Alfnes Erlend 
Published: June 2015

Purpose
– Engineer-to-order (ETO) supply chains involve multiple companies for performing complex projects. The ability to effectively coordinate cross-business activities is essential to avoid delays, cost overruns and quality problems. Coordination is related to a number of contingent factors that need to be better comprehended. The purpose of this paper is to highlight such contingent factors and to analyse their effect on the occurrence of project delays.

Design/methodology/approach
– A multiple case study is used to investigate the moderating factors affecting coordination in projects carried out in an ETO supply chain. Such factors are examined through a cross-analysis of six shipbuilding projects based on data from interviews, project documentation and clips from the media press.

Findings
– In ETO supply chains, the engineering and production activities involve mutual interdependences that need to be coordinated. The findings suggest that both the integration of engineering and production and the production capability are the most critical factors influencing coordination in an ETO supply chain.

Research limitations/implications
– The study was carried out within shipbuilding projects as a setting to represent the ETO domain. To extend the findings, further research can examine other types of projects, such as: oil and gas, construction, military and aerospace.

Practical implications
– In practice, there is no “one-fits-all” solution for coordination. Each project represents a unique context which has specific objectives, actors and constraints. From that perspective, this study provides a basis to comprehend coordination in a complex setting.

Originality/value
– This study builds knowledge upon coordination by generating a number of propositions regarding the effectiveness of coordination on avoiding delays in complex projects carried out in ETO supply chains. Focusing on the engineering and production activities, the authors extend the existing theory by demonstrating that coordination can vary according to the level of several moderating factors.
Lifetime trauma victimization and PTSD in relation to psychopathy and antisocial personality disorder in a sample of incarcerated women and men
Authors: Gobin Robyn L , Reddy Madhavi K. , Zlotnick Caron , Johnson Jennifer E. 
Published: June 2015

Purpose
– Antisocial personality disorder (ASPD) and psychopathy are similar, but distinct, psychiatric conditions that are common in male and female inmates; a segment of the population with high rates of trauma exposure. It is unclear whether specific types of lifetime trauma are associated with ASPD and psychopathy in incarcerated women and men. Furthermore, the unique roles of post-traumatic stress disorder (PTSD) symptom severity and trauma victimization in antisocial personality disturbance are not well-understood. The paper aims to discuss these issues.

Design/methodology/approach
– This study investigated associations between trauma variables (different kinds of traumatic experiences and PTSD) and antisocial personality variables (ASPD and psychopathy) in a sample of incarcerated women and men who participated in a randomized clinical trial for major depressive disorder. In total, 88 incarcerated men and women were assessed for ASPD diagnosis, psychopathy severity, PTSD symptom severity, and history of physical, sexual, and crime-related trauma. Regression analyses predicted ASPD or psychopathy from trauma variables, controlling for gender.

Findings
– Physical trauma was the only form of trauma that was significantly related to psychopathy. Physical trauma and crime-related trauma were associated with ASPD. PTSD symptom severity was not associated with psychopathy or ASPD.

Originality/value
– There are associations between some kinds of lifetime trauma exposure and current ASPD/psychopathy in the target sample, but these associations do not appear to be mediated through current PTSD symptoms.
Influence of offence type and prior imprisonment on risk of death following release from prison: a whole-population linked data study
Authors: Jama-Alol Khadra Abdi , Malacova Eva , Ferrante Anna , Alan Janine , Stewart Louise , Preen David 
Published: June 2015

Purpose
– The purpose of this paper is to examine the influence of offence type, prior imprisonment and various socio-demographic characteristics on mortality at 28 and 365 days following prison release.

Design/methodology/approach
– Using whole-population linked, routinely collected administrative state-based imprisonment and mortality data, the authors conducted a retrospective study of 12,677 offenders released from Western Australian prisons in the period 1994-2003. Cox proportional hazards regression was used to examine the association between mortality at 28 and 365 days post-release and offence type, prior imprisonment, and a range of socio-demographic characteristics (age, gender, social disadvantage and Indigenous status).

Findings
– Overall, 135 (1.1 per cent) died during the 365 days follow-up period, of these, 17.8 per cent (n=24) died within the first 28 days (four weeks) of their index release. Ex-prisoners who had committed drug-related offences had significantly higher risk of 28-day post-release mortality (HR=28.4; 95 per cent CI: 1.3-615.3, p=0.033), than those who had committed violent (non-sexual) offences. A significant association was also found between the number of previous incarcerations and post-release mortality at 28 days post-release, with three prior prison terms carrying the highest mortality risk (HR=73.8; 95 per cent CI: 1.8-3,092.5, p=0.024). No association between mortality and either offence type or prior imprisonment was seen at 365 days post-release.

Originality/value
– Post-release mortality at 28 days was significantly associated with offence type (with drug-related offences carrying the greatest risk) and with prior imprisonment, but associations did not persist to 365 days after release. Targeting of short-term transitional programmes to reduce preventable deaths after return to the community could be tailored to these high-risk ex-prisoners.
Sensory Characterization and Consumer Preference Mapping of Fresh Sausages Manufactured with Goat and Sheep Meat
Authors: Paulos Kátia , Rodrigues Sandra , Oliveira António Filipe , Leite Ana , Pereira Etelvina , Teixeira Alfredo 
Published: June 2015

AbstractThe main objective of this study was the sensory characterization, by a taste and a consumers’ panel, of fresh sausages from 140 culled goats and 140 culled ewes. Species and type of preparation effects were studied. All data were previously analyzed by analysis of variance. Taste panel data were analyzed by a Generalized Procrustes Analysis (GPA). Consumers’ panel data were analyzed by Preference Mapping. The 1st 2 factors explained 88.22% of total variation in GPA. Different sausages samples were perfectly differentiated by assessors. Goat sausages have been considered harder, more fibrous, and less juicy than sheep sausages. The panelists observed that sheep sausages without paprika had greater intensity of flavor, tasted spicy, and had an off‐odor, while goat sausages with paprika were considered sweeter. Consumers’ panel did not show any preference for the different types of sausages. This means that all types of sausages can have market opportunity.
Association between history of psychosis and cardiovascular disease in bipolar disorder
Authors: Prieto Miguel L , McElroy Susan L , Hayes Sharonne N , Sutor Bruce , Kung Simon , Bobo William V , Fuentes Manuel E , Cuellar‐Barboza Alfredo B , Crow Scott , Ösby Urban , Chauhan Mohit , Westman Jeanette , Geske Jennifer R , Colby Colin L , Ryu Euijung , Biernacka Joanna M , Frye Mark A 
Published: June 2015

ObjectivesTo determine whether clinical features of bipolar disorder, such as history of psychosis, and cardiovascular disease (CVD) risk factors contribute to a higher risk of CVD among patients with bipolar disorder.MethodsThis cross‐sectional study included a sample of 988 patients with bipolar I or bipolar II disorder or schizoaffective bipolar type confirmed by the Structured Clinical Interview for DSM‐IV‐TR disorders (SCID). Medical comorbidity burden was quantified utilizing the Cumulative Illness Severity Rating Scale (CIRS). This 13‐item organ‐based scale includes cardiac disease severity quantification. Confirmed by medical record review, patients who scored 1 (current mild or past significant problem) or higher in the cardiac item were compared by logistic regression to patients who scored 0 (no impairment), adjusting for CVD risk factors that were selected using a backwards stepwise approach or were obtained from the literature.ResultsIn a multivariate model, age [odds ratio (OR) = 3.03, 95% confidence interval (CI): 1.66–5.54, p < 0.0001], hypertension (OR = 2.43, 95% CI: 1.69–3.55, p < 0.0001), and history of psychosis (OR = 1.48, 95% CI: 1.03–2.13, p = 0.03) were associated with CVD. When CVD risk factors from the literature were added to the analysis, age (OR = 3.19, 95% CI: 1.67–6.10, p = 0.0005) and hypertension (OR = 2.46, 95% CI: 1.61–3.76, p < 0.01) remained significant, with psychosis being at the trend level (OR = 1.43, 95% CI: 0.96–2.13, p = 0.08).ConclusionsThe phenotype of psychotic bipolar disorder may reflect higher illness severity with associated cardiac comorbidity. Further studies are encouraged to clarify the effect of the disease burden (i.e., depression), lifestyle, and treatment interventions (i.e., atypical antipsychotics) on this risk association.
Mycophenolate mofetil and Sirolimus as second or further line treatment in children with chronic refractory Primitive or Secondary Autoimmune Cytopenias: a single centre experience
Authors: Miano Maurizio , Scalzone Maria , Perri Katia , Palmisani Elena , Caviglia Ilaria , Micalizzi Concetta , Svahn Johanna , Calvillo Michaela , Banov Laura , Terranova Paola , Lanza Tiziana , Dufour Carlo , Fioredda Francesca 
Published: June 2015

SummaryThe management of refractory autoimmune cytopenias in childhood is challenging due to the lack of established evidence on escalating treatments. The long‐term efficacy of immunosuppressive drugs was evaluated in children with refractory autoimmune cytopenias referred to the Haematology Unit of the Gaslini Children's Hospital between 2001 and 2014. Patients were grouped into three categories: autoimmune lymphoproliferative syndrome (ALPS), ALPS‐related syndrome (at least one absolute/primary additional criterion for ALPS) and primary autoimmune cytopenia (PAC, cytopenia with no other immunological symptoms/signs). Fifty‐eight children (aged 1–16 years) entered the study: 12 were categorized with ALPS, 24 were ALPS‐related and 22 had PAC. Five didn't receive treatment. Fifty‐three were initially treated with steroids/intravenous immunoglobulin. Fourteen responded, whereas 39 did not. Of these 39 patients, 34 (87%) received mycophenolate mofetil (MMF) as second/further‐line treatment and 22 (65%) responded. Within these 34 subjects, ALPS patients responded better (11/11, 100%) than the two other groups pooled together (11/23, 48%; P = 0·002). Sirolimus was given as second/further‐line treatment to 16 children, and 12 (75%) responded, including 8 who previously failed MMF therapy. Median follow‐up was 3·46 years. MMF and Sirolimus were well‐tolerated and enabled partial/complete and sustained remission in most children. These drugs may be successfully and safely used in children with refractory autoimmune cytopenias with or without ALPS/ALPS‐related disorders and may represent a valid second/further line option.
Student ePortfolios to develop reflective skills and demonstrate competency development: Evaluation of a curriculum pilot project
Authors: Walton J. N. , Gardner K. , Aleksejuniene J. 
Published: June 2015

AbstractIntroductionThe University of British Columbia Faculty of Dentistry developed a longitudinal curriculum pilot project to assess the usefulness of portfolios for dental students to develop reflective skills and demonstrate competency development, and to examine relationships between portfolio grades and clinical success.Materials and MethodsStudents in one dental class created portfolios with reflections on examples relevant to eight selected competency statements each year of the program. As part of our program evaluation, we set out to look at trends in portfolio grades, meta‐reflection skills, student and faculty views of the project, and relationships among portfolio grades, 4th year clinical grades and faculty rankings.ResultsPortfolio grades improved from years 1 to 3, dropping off slightly in year 4. The highest level of internal consistency for grades within and between years occurred with Competency 42, while the lowest level occurred with Competency 4. Most students were able to demonstrate meta‐reflection by 4th year. Students generally agreed with portfolios and reflection in concept, but suggested a looser structure, and they shared concerns with faculty about the workload involved. Portfolio grades did not correlate with clinical course grades (P = 0.092), but they did correlate significantly with faculty rankings except for year 1.ConclusionWhile portfolio grades for reflections were not consistent, and they did not quite correlate with clinical course grades, they correlated strongly with faculty rankings. Future use of portfolios atUBCDentistry will be enhanced by increasing curricular support regarding both competency development and the importance of reflection for professionals, decreasing workload by focusing on five Key Competencies, incorporating more formative and face‐to‐face feedback, and providing greater opportunities for peer sharing.
Dental students' experiences of treating orthodontic emergencies – a qualitative assessment of student reflections
Authors: Jones K. , Popat H. , Johnson I. G. 
Published: June 2015

AbstractIntroductionProfessional regulatory bodies in the UK and Europe state that dental graduates should be able to manage orthodontic emergency patients. Therefore, the aim of this study was to explore dental student experiences of treating orthodontic emergencies within a teaching institution.Materials and methodThis study was designed as a single‐centre evaluation of teaching based in a UK university orthodontic department. The participants were fourth‐year dental students who treated orthodontic emergency patients under clinical supervision as part of the undergraduate curriculum. Student logbook entries for one academic year detailing the types of emergencies treated and structured, reflective commentaries for each procedure were analysed using thematic analysis methods. The total numbers and types of orthodontic emergencies treated by students were presented. Overall, self‐reported student confidence in managing orthodontic emergencies was calculated. Themes, which represented student reflections, were identified.ResultsSeventy‐two students participated in the study. Overall, 69% of students stated they were confident in managing orthodontic emergencies. Students treated a range of emergencies, of which the most frequent was debonded brackets (38%). Reflections from student commentaries were housed under a primary theme of building procedural confidence. Three subthemes were identified: (i) theory‐practice integration; (ii) expanding clinical experience; and (iii) importance of a supportive clinical learning environment.ConclusionThe majority of dental students were confident in managing orthodontic emergencies. Theoretical knowledge supplemented by exposure to a range of clinical problems within a supported learning environment made students feel more confident.
Understanding innate immunity and inflammation in acne: implications for management
Authors: Dreno B. , Gollnick H.P.M. , Kang S. , Thiboutot D. , Bettoli V. , Torres V. , Leyden J. ,   the Global Alliance to Improve Outcomes in Acne
Published: June 2015

AbstractAcne has long been understood to have a complex physiological basis involving several main factors: hormonally‐stimulated sebum production, abnormal keratinization of the pilosebaceous duct, and an inflammatory immune response to Propionibacterium acnes. Recent studies at the molecular and cellular level have begun clarifying how all of these factors interact, and the role of the innate immune system is better appreciated. Inflammation has been demonstrated in all acne lesions ‐ the preclinical microcomedo, comedones, inflammatory lesions, ‘post‐inflammatory’ erythema or hyperpigmentation, and scarring. Inflammation localized to the pilosebaceous unit can be considered the defining feature of acne and should be addressed via multiple therapeutic pathways. Clinicians tend to think oral antibiotics should be used to ‘calm’ inflammatory acne, but there is good evidence showing that topical retinoids also have anti‐inflammatory properties as a class effect. For best therapeutic outcomes, most patients with acne should be treated first line with a topical retinoid plus an antimicrobial agent, as has been demonstrated in thousands of patients involved in clinical trials and recommended by the Global Alliance to Improve Outcomes in Acne for more than a decade. Moving away from reliance on antibiotic therapy for acne is particularly important in an era of worsening antimicrobial resistance and worldwide calls to reduce antibiotic use. Improved understanding about the role of P. acnes and the innate immune system in acne should help clinicians in designing efficacious treatment strategies.
Safety and efficacy of adapalene 0.1% / benzoyl peroxide 2.5% in the long‐term treatment of predominantly moderate acne with or without concomitant medication – results from the non‐interventional cohort study ELANG
Authors: Gollnick H.P.M. , Friedrich M. , Peschen M. , Pettker R. , Pier A. , Streit V. , Jöstingmeyer P. , Porombka D. , Rojo Pulido I. , Jäckel A. 
Published: June 2015

AbstractBackgroundAcne is a chronic inflammatory disease requiring long‐term treatment. The fixed‐dose combination adapalene 0.1%/benzoyl peroxide 2.5% (adapalene‐BPO) is indicated for the once‐daily topical treatment of Acne vulgaris when comedones, papules and pustules are present.ObjectiveThe main objectives of this non‐interventional study were to assess long‐term efficacy and safety of adapalene‐BPO in moderate to severe acne with and without concomitant medication.MethodsPatients with moderate to severe acne received adapalene‐BPO alone or in combination with concomitant medication over a course of 9 months. The primary efficacy endpoint was changes in acne severity according to the Leeds Revised Acne Grading System; secondary endpoints included treatment success assessed by the patient and safety.ResultsIn total, 5131 patients were eligible for efficacy and 5141 for safety evaluation. The majority of patients (78.8%) received adapalene‐BPO alone. About 21.2% received adapalene‐BPO in combination with another agent, mostly topical antibiotics (8.8%) or systemic antibiotics (8.7%). Mean (±SD) acne severity improved from 5.6 ± 1.5 at baseline to 3.3 ± 1.9 at month 3, and further to 1.9 ± 1.9 at month 9 (both P < 0.0001). The degree of improvement correlated significantly with the severity at baseline. After 3 and 9 months of treatment, the facial skin was cleared completely (no more visible acne lesions) in 420 (8.2%) and 1326 patients (25.8%), respectively. A therapeutic effect was noted by the patients after a median time of 3 weeks (range: from 1 day to 12 weeks). No serious adverse events were reported. Facial skin irritations, mostly mild to moderate, occurred in 49.5% of patients and led to discontinuation in only 1.7% of cases.ConclusionIn consistence with previous clinical findings, the use of adapalene‐BPO in daily practice routine is safe and effective in the long‐term management of patients with moderate to severe acne.
On the interaction between tree canopy position and environmental effects on soil attributes and plant communities
Authors: Soliveres Santiago , Eldridge David J. , Müller Jonathan D. , Hemmings Frank , Throop Heather L. 
Published: June 2015

AbstractQuestionsUnderstanding how trees affect their understorey plants and soils is crucial to understand savanna ecosystems. Most studies focus on the differences between canopy and open microsites, but how do different positions within large tree canopies influence soils and plants? Are these potential differences likely to change depending on environmental conditions (i.e. annual rainfall and grazing)?LocationOne hundred sites across a rainfall gradient (220–1400 mm) in NSW, Australia.MethodsWe measured the cover, richness and community composition of understorey plants and 12 soil attributes related to infiltration, erodibility and fertility across three positions within the canopy of large eucalypts (trunk, mid‐canopy and edge) and in open areas. We also estimated the percentage similarity in plant communities across microsites, and the percentage species within the landscape occurring solely in one of the four microsites assayed. We tested the interactions between the effect of environmental conditions (rainfall and grazing) and canopy position on all these soil and vegetation attributes.ResultsSoil attributes explained ~50% of the effect of trees on understorey plants, and soil attributes improved with proximity to the trunk and increasing rainfall. The effect of canopy position × rainfall interactions depended on the response variable considered. These interactions did not affect soil attributes, the percentage of facilitation‐obligate species or species richness, and weakly affected plant composition. However, we found a strong reduction in similarity among plant communities within edge and mid‐canopy compared with open sites towards drier environments, and canopy position × rainfall interactions also significantly affected plant cover. We attribute these weak interactions between canopy position and environmental conditions to richness or the frequency of facilitation to the high turnover of facilitated species across microsites and across different environmental conditions.ConclusionsOur study can be used to better understand community dynamics in ecosystems with scattered trees by showing the differential effects of trees on their understorey. Our results also contribute to the body of research on the relationships between plant–plant interactions and the environment by illustrating the importance of gradient length and the number of different microsites considered.
Genome‐wide association mapping of cadmium accumulation in different organs of barley
Authors: Wu Dezhi , Sato Kazuhiro , Ma Jian Feng 
Published: June 2015

Summary

The threshold value of cadmium (Cd) concentration in grains of barley (Hordeum vulgare) is the lowest among cereal crops; however, it is poorly understood how Cd accumulation in barley grain is genetically controlled.

We investigated genotypic variation in Cd accumulation of different organs in 100 accessions from a subset of the barley core collection using both hydroponic and Cd‐contaminated soil culture. We also performed a genome‐wide association (GWA) mapping for Cd accumulation in different organs.

A large genotypic variation in the Cd concentration was found in all organs. There was a good correlation between shoot Cd of solution and soil culture, the shoot Cd and grain Cd, but no correlation between the root Cd and grain Cd. GWA mapping detected 9 quantitative trait loci (QTL) for root Cd, 21 for shoot Cd, 14 for root‐to‐shoot translocation and 15 for grain Cd. A common QTL for the shoot Cd and root‐to‐shoot translocation was found at 132.6 cM on chromosome 5H. Two major QTL for grain Cd were identified on chromosome 2H and chromosome 5H.

The genetic variation in Cd accumulation and major QTL detected provide useful information helpful for cloning candidate genes for Cd accumulation and breeding low‐Cd barley cultivars in future.