bluuebunny/crossref_metadata_2025_split huggingface dataset:
Long-term operation and dynamic response of dissimilatory nitrate reduction to ammonium process under low-frequency infrared electromagnetic field
Authors: Xie Yuyang , Wang Zhibin , Ismail Sherif , Ni Shou-Qing 
Published: July 2024

AbstractDissimilatory nitrate reduction to ammonium (DNRA) received more attention for its ability to recover ammonium. This study investigated the possibility of low-frequency infrared electromagnetic field (IR-EMF) to improve DNRA. The optimal IR-EMF intensity of 0.04 μT could effectively improve DNRA activity of nonwoven fabric membrane bioreactors. In the long-term operation, the average ammonium conversion efficiency was enhanced by 117.7% and 62.5% under 0.04 μT and 0.06 μT IR-EMF, respectively. The highest nrfA-gene abundance and potential DNRA rate were obtained under 0.04 μT IR-EMF exposure. Bacteroidetes fragilis, Shewanelle oneidensis MR-1, and Thauera sp. RT1901 were selected to investigate the dynamic response of nitrogen transformation and energy metabolism to IR-EMF. The transcriptome sequencing and RT-qPCR results suggested that IR-EMF could enhance both denitrification and DNRA process, mainly by improving ATP synthesis to boost metabolic activity. This study provided an efficient method for the nitrogen recovery via DNRA process by applying IR-EMF.
The Canadian Fire Spread Dataset
Authors: Barber Quinn E. , Jain Piyush , Whitman Ellen , Thompson Dan K. , Guindon Luc , Parks Sean A. , Wang Xianli , Hethcoat Matthew G. , Parisien Marc-André 
Published: July 2024

AbstractSatellite data are effective for mapping wildfires, particularly in remote locations where monitoring is rare. Geolocated fire detections can be used for enhanced fire management and fire modelling through daily fire progression mapping. Here we present the Canadian Fire Spread Dataset (CFSDS), encompassing interpolated progressions for fires >1,000 ha in Canada from 2002–2021, representing the day-of-burning and 50 environmental covariates for every pixel. Day-of-burning was calculated by ordinary kriging of active fire detections from the Moderate Resolution Imaging Spectroradiometer and the Visible Infrared Imaging Radiometer Suite, enabling a substantial improvement in coverage and resolution over existing datasets. Day of burning at each pixel was used to identify environmental conditions of burning such as daily weather, derived weather metrics, topography, and forest fuels characteristics. This dataset can be used in a broad range of research and management applications, such as retrospective analysis of fire spread, as a benchmark dataset for validating statistical or machine-learning models, and for forecasting the effects of climate change on fire activity.
Curation of historical phenotypic wheat data from the Czech Genebank for research and breeding
Authors: Svoboda Pavel , Holubec Vojtěch , Reif Jochen C. , Berkner Marcel O. 
Published: July 2024

AbstractClimate change and population growth are putting increasing pressure on global food security. The development of high-yielding varieties for important crops such as wheat is crucial to meet these challenges. The basis for this is extensive exploitation of beneficial genetic variation resting in genebanks around the world. Selecting suitable donor genotypes from the vast number of wheat accessions stored in genebanks is a difficult task and depends critically on the density of information on the performance of individual accessions. Therefore, this study aimed to access phenotypic data from the Czech genebank, storing over 13,000 wheat accessions. We curated and analyzed data on heading date, plant height, and thousand grain weight for more than one-third of all available accessions regenerated across 70 years. The data underwent analysis using a linear mixed model, revealing high quality of curated data with heritability reaching 99%. The raw data, but also derived data such as the best linear unbiased estimations, are now available for the wheat collection of the Czech genebank for research and breeding.
Site-specific apparent optimum air temperature for vegetation photosynthesis across the globe
Authors: Pan Li , Xiao Xiangming , Yao Yuan , Pan Baihong , Yin Chenglong , Meng Cheng , Qin Yuanwei , Zhang Chenchen 
Published: July 2024

AbstractThe apparent optimum air temperature for vegetation photosynthesis (Topt) is a key temperature parameter in terrestrial ecosystem models estimating daily photosynthesis or gross primary production (GPP, g C/m2/day). To date, most models use biome-specific Topt (Topt-biome) parameter values. Given vegetation acclimation and adaptation to local climate, site-specific Topt (Topt-site) is needed to reduce uncertainties in estimating daily GPP across the scales from site to region and the globe. Previous studies have demonstrated using the Enhanced Vegetation Index (EVI) derived from Moderate Resolution Imaging Spectroradiometer (MODIS) images and daytime air temperature data to estimate the Topt-site at the eddy covariance tower sites. This study used MODIS-derived EVI and ERA5 climate data to estimate and generate global Topt-site data products from 2000 to 2019. The Topt-site of individual pixels within a biome has large variation, which clearly cannot be represented accurately by the widely used Topt-biome. Therefore, using this global dataset of Topt-site estimates might significantly affect GPP simulation in current ecosystem models.
Plant-level intensity of energy and CO2 emissions for Portland cement in Guizhou of Southwest China 2019–2022
Authors: Wang Wenhao , Ye Minghua , Shi Yanfang , Xiao Dongchen 
Published: July 2024

AbstractLow-carbon development of ordinary Portland cement industry is of great significance to China’s target “to peak carbon dioxide emissions before 2030 and to achieve carbon neutrality before 2060”. Neglecting the regional heterogeneity in China, few studies emphasized the status and developments of energy intensity and CO2 emissions of ordinary Portland cement industry in Guizhou of Southwest China. To bridge this knowledge gap, we present an annual intensity dataset of energy and CO2 emissions at plant-level for Guizhou’s ordinary Portland cement industry, which involves the details of clinker rotary kilns, yearly production of clinker and cement products, fuel consumption and electricity consumption, total CO2 emission of cement products, energy intensity indicators of clinker and cement products, utilization ratio of solid-waste in clinker and cement production, and CO2 emission factors of cement products. It is an important supplement and to existing energy intensity and CO2 emissions estimates at plant-level and provincial official emissions inventories that converges all regions of China.
Characteristics and factors influencing the expansion of urban construction land in China
Authors: Zhang Xiaodong , Han Haoying 
Published: July 2024

AbstractAs a new product of rapid urbanization, the sprawl of urban construction land can objectively reflect urban land use efficiency, which is of great significance to China's new urban construction. This study aimed to summarize the expansion patterns and utilization efficiency of urban construction land in China from the perspectives of the status, speed and trends of expansion, and to uncover the key factors that lead to the differential distribution of the expansion of construction land. It can also provide land management experience for other countries with rapid expansion of construction land. The results show the following. (1) The expansion of China's construction land presents a "point–line–plane" pattern of evolution, forming changing stages of point-like aggregation, linear series and planar spread. (2) China's construction land shows the characteristics of disorderly spread, a low utilization rate and low output efficiency. The speed of expansion presents clear characteristics of being high in the east and low in the west, mostly concentrated in the Yangtze River Delta, Pearl River Delta and the Beijing–Tianjin–Hebei urban agglomeration. Shanghai, Beijing, Shenzhen and Guangzhou have the highest intensity of construction land use. In Shandong Peninsula and eastern coastal areas, the intensity of the construction land use is generally high. In Xinjiang and Xizang, the intensity of construction land use is relatively low. (3) The urban economic level, population size, industrial structure, foreign investment and land policies have significant effects on the spatial distribution of the expansion of construction land.
Mapping multimorbidity progression among 190 diseases
Authors: Han Shasha , Li Sairan , Yang Yunhaonan , Liu Lihong , Ma Libing , Leng Zhiwei , Mair Frances S. , Butler Christopher R. , Nunes Bruno Pereira , Miranda J. Jaime , Yang Weizhong , Shao Ruitai , Wang Chen 
Published: July 2024

Abstract
Background
Current clustering of multimorbidity based on the frequency of common disease combinations is inadequate. We estimated the causal relationships among prevalent diseases and mapped out the clusters of multimorbidity progression among them.

Methods
In this cohort study, we examined the progression of multimorbidity among 190 diseases among over 500,000 UK Biobank participants over 12.7 years of follow-up. Using a machine learning method for causal inference, we analyzed patterns of how diseases influenced and were influenced by others in females and males. We used clustering analysis and visualization algorithms to identify multimorbidity progress constellations.

Results
We show the top influential and influenced diseases largely overlap between sexes in chronic diseases, with sex-specific ones tending to be acute diseases. Patterns of diseases that influence and are influenced by other diseases also emerged (clustering significance Pau > 0.87), with the top influential diseases affecting many clusters and the top influenced diseases concentrating on a few, suggesting that complex mechanisms are at play for the diseases that increase the development of other diseases while share underlying causes exist among the diseases whose development are increased by others. Bi-directional multimorbidity progress presents substantial clustering tendencies both within and across International Classification Disease chapters, compared to uni-directional ones, which can inform future studies for developing cross-specialty strategies for multimorbidity. Finally, we identify 10 multimorbidity progress constellations for females and 9 for males (clustering stability, adjusted Rand index >0.75), showing interesting differences between sexes.

Conclusion
Our findings could inform the future development of targeted interventions and provide an essential foundation for future studies seeking to improve the prevention and management of multimorbidity.
Interplay of Semantic Plausibility and Word Order Canonicity in Sentence Processing of People With Aphasia Using a Verb-Final Language
Authors: Sung Jee Eun , DeDe Gayle , Park Jimin 
Published: July 2024

Purpose:
The Western Aphasia Battery is widely used to assess people with aphasia (PWA). Sequential Commands (SC) is one of the most challenging subtests for PWA. However, test items confound linguistic factors that make sentences difficult for PWA. The current study systematically manipulated semantic plausibility and word order in sentences like those in SC to examine how these factors affect comprehension deficits in aphasia.

Method:
Fifty Korean speakers (25 PWA and 25 controls) completed a sentence–picture matching task that manipulated word order (canonical vs. noncanonical) and semantic plausibility (plausible vs. less plausible). Analyses focused on accuracy and aimed to identify sentence types that best discriminate the groups. Additionally, we explored which sentence type serves as the best predictor of aphasia severity.

Results:
PWA demonstrated greater difficulties in processing less plausible sentences than plausible ones compared to the controls. Across the groups, noncanonical and less plausible sentences elicited lower accuracy than canonical and plausible sentences. Notably, the accuracy of PWA and control groups differed in noncanonical and less plausible sentences. Additionally, aphasia severity significantly correlated with less plausible sentences.

Conclusion:
Even in languages with flexible word order, PWA find it challenging to process sentences with noncanonical syntactic structures and less plausible semantic roles.
How People Living With Amyotrophic Lateral Sclerosis Use Personalized Automatic Speech Recognition Technology to Support Communication
Authors: Cave Richard 
Published: July 2024

Purpose:
Amyotrophic lateral sclerosis (ALS) is a progressive, ultimately fatal disease causing progressive muscular weakness. Most people living with ALS (plwALS) experience dysarthria, eventually becoming unable to communicate using natural speech. Many wish to use speech for as long as possible. Personalized automated speech recognition (ASR) model technology, such as Google's Project Relate, is argued to better recognize speech with dysarthria, supporting maintenance of understanding through real-time captioning. The objectives of this study are how plwALS and communication partners use Relate in everyday conversation over a period of up to 12 months and how it may change with any decline in speech over time.

Method:
This study videoed interactions between three plwALS and communication partners. We assessed ASR caption accuracy and how well they preserved meaning. Conversation analysis was used to identify participants' own organizational practices in the accomplishment of interaction. Thematic analysis was used to understand better the participants' experiences of using ASR captions.

Results:
All plwALS reported lower-than-expected ASR accuracy when used in conversation and felt ASR captioning was only useful in certain contexts. All participants liked the concept of live captioning and were hopeful that future improvements to ASR accuracy may support their communication in everyday life.

Conclusions:
Training is needed on best practices for customization and practical use of ASR technology and for the limitations of ASR in conversational settings. Support is needed for those less confident with technology and to reduce misplaced allocation of ownership of captioning errors, risking negative effects on psychological well-being.
COVID-19: Kollateralschäden in der Kopf-Hals-Onkologie und Präventivmaßnahmen für künftige Pandemien
Authors: Wilhelm Christian , Radeloff Katrin , Scherzad Agmal , Scheich Matthias , Hagen Rudolf 
Published: July 2024

ZUSAMMENFASSUNGDer Beginn der COVID-19-Pandemie führte zu enormen Herausforderungen für die globale Gesundheitsversorgung, da rasch Kapazitäten und Ressourcen für die Behandlung von COVID-19-Patienten zur Verfügung gestellt werden mussten. Dadurch kam es auch zu Einschränkungen bei der Versorgung onkologischer Patienten mit Kopf-Hals-Malignomen. Diese Übersichtsarbeit fasst die Entwicklung der Tumorinzidenzen während der Pandemie, die international erarbeiteten Richtlinien zur Versorgung von Patienten mit Kopf-Hals-Malignomen und Studien zur Verzögerung onkologischer Therapien sowie der Mortalität zusammen. Darüber hinaus werden Auswirkungen auf die psychische Gesundheit der Patienten, die psychosozialen Folgen sowie ethische Fragen beleuchtet. Perspektivisch werden Präventivmaßnahmen für derartige negative Kollateraleffekte bei künftigen Pandemien am Beispiel eines Konzepts für eine Applikationssoftware (App)-basierte digitale Betreuung von Patienten mit Kopf-Hals-Tumoren diskutiert.
Do Disease Parameters Related to Primary Sjögren's Syndrome have
an Impact on the Severity of Co-Existing Fibromyalgia Syndrome or Vice
Versa?
Authors: Kaban Nedim , Bakay Umut , Soylu Ali Can , Gürer Gülcan , Harman Halil 
Published: July 2024

Abstract
Objectives We aimed to examine whether primary Sjögren's syndrome
(pSS)-related parameters may affect the severity of co-existing fibromyalgia
syndrome (FMS) in pSS patients or vice versa; co-existing FMS might have an
influence on the severity of sicca symptoms and disease activity measurements in
pSS.
Method Our study included a total of 49 pSS patients (24 with concomitant
FMS; 25 without FMS) and 30 patients with primary FMS (pFMS). The EULAR
Sjögren's Syndrome Patient Reported Index (ESSPRI) and the EULAR
Sjögren's Syndrome Disease Activity Index (ESSDAI) were used to evaluate
pSS symptoms and disease activity. Sicca symptom severity (SSS) scores were
recorded on a visual analogue scale for pSS patients. A minor salivary gland
biopsy was performed in 34 pSS patients. The Revised Fibromyalgia Impact
Questionnaire (FIQR) was used to evaluate the total spectrum of
fibromyalgia-related problems.
Results There was no statistically significant difference between disease
activity measurements (ESSDAS, ESSPRI) in pSS patients with FMS and pSS patients
(p=0.913, p=0.952, respectively). However, SSS scores were significantly higher
in pSS patients with FMS than in pSS patients (p=0.045). There was no
statistically significant difference between pFMS and pSS patients with FMS in
terms of FIQR scores (p=0.149).
Conclusions It was demonstrated that the severity of fibromyalgia assessed
by FIQR is comparable between both groups.
Cerebroprotective Potential of Andrographolide Nanoparticles: In
silico and In vivo Investigations
Authors: Rudrala Lakshmi Charitha , Challa Ranadheer Reddy , Subramanyam Sibbala , Ayyappa Gouru Sampath , Singh Gagandeep , Sirisha Mulukuri N.V. L. , Pasala Praveen Kumar , Dintakurthi Prasanth Sree Naga Bala Krishna , Gajula Somasekhar , Rudrapal Mithun 
Published: July 2024

AbstractIschemic stroke remains the leading cause of death and disability, while the main
mechanisms of dominant neurological damage in stroke contain oxidative stress
and inflammation. Docking studies revealed a binding energy of − 6.1 kcal/mol
for AG, while the co-crystallized ligand (CCl) exhibited a binding energy of
− 7.3 kcal/mol with NOS. AG demonstrated favourable hydrogen bond interactions
with amino acids ASN A:354 and ARG A:388 and hydrophobic interactions with GLU
A:377. Molecular dynamics simulations throughout 100 ns indicated a binding
affinity of − 27.65±2.88 kcal/mol for AG, compared to − 18.01±4.02 kcal/mol for
CCl. These findings suggest that AG possesses a superior binding affinity for
NOS compared to CCl, thus complementing the stability of NOS at the docked
site.AG has limited applications owing to its low bioavailability, poor water
solubility, and high chemical and metabolic instability.The fabrication method
was employed in the preparation of AGNP, SEM analysis confirmed spherical shape
with size in 19.4±5 nm and investigated the neuroprotective effect in cerebral
stroke rats induced by 30 min of carotid artery occlusion followed by 4 hr
reperfusion, evaluated by infarction size, ROS/RNS via GSH, MPO, NO
estimationand AchE activity, and monitoring EEG function. Cortex and hippocampal
histology were compared between groups. AGNP treatment significantly decreased
Infarction size and increased GSH levels (p<0.01**), decreased MPO
(p<0.01**), NO (p<0.01**), AchE
(p<0.01**), restored to normal EEG amplitude, minimizing
unsynchronized polyspikes and histological data revealed that increased
pyramidal cell layer thickness and decreased apoptotic neurons in hippocampus,
cortex appeared normal neurons with central large vesicular nuclei, containing
one or more nucleoli in compared to AG treatment. Based on brain biochemical,
histopathology reports AGNP exhibited significant cerebroprotective activity
compared to AG on ischemic rats.
Genito Urinary Infection and Urinary Tract Infection in Patients with
Type 2 Diabetes Mellitus Receiving SGLT2 Inhibitors: Evidence from a Systematic
Literature Review of Landmark Randomized Clinical Trial
Authors: Arshad Mawrah , Hoda Farazul , Siddiqui Nasir Ali , Najmi Abul Kalam , Ahmad Mohammad 
Published: July 2024

Abstract
Background and purpose SGLT2 inhibitors are class of drugs that are used
in adults with type 2 diabetes through a novel mechanism of action by reducing
renal tubular glucose reabsorption, leading to a reduction in blood glucose
without stimulating insulin release. In this systematic review, we report the
effects of treatment with SGLT2 inhibitors on urinary tract infection (UTI) and
genitourinary infection (GUI).
Method The study integrated data from landmark trials of SGLT2 inhibitors
(CANVAS, CREDENCE, DECLARE–TIMI 58, and EMPA-REG) to interpret the association
of SGLT2 inhibitors with genital infection (GI) and UTI. We reported the review
following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses
(PRISMA) statement. The primary outcome was a composite of participants
reporting UTI and GUI prescribed on SGLT2 inhibitors.
Results The analysis of four studies involving 38,723 participants
revealed incidences of both UTIs and GUI. In the SGLT2 inhibitor group,
comprising 21,266 participants, 222 (1.04%) experienced UTIs, and 477 (2.24%)
reported GUI. In contrast, among the placebo group consisting of 17,457
participants, 201 (1.15%) reported UTIs, and 70 (0.40%) reported genital
infections. These findings underscore the elevated risk associated with SGLT2
inhibitor use, particularly regarding GUI, necessitating careful consideration
in clinical practice and patient management strategies.
Conclusion The incidence of UTIs and particularly more pronounced GUI
associated with SGLT2 inhibitors highlights the importance of careful risk
assessment and monitoring in clinical decision-making, underscoring the need for
patient management strategies.
Efficacy of Ventriculoperitoneal Shunt for Postoperative Central Nervous System Infection Complicated with Hydrocephalus
Authors: Chen FuMei , Wang Na , Wang Li , He ZhiYang , Xu KangLi , Zhan TianXiang , Zhou Qian , Wang Hao , Yang XiaoFeng 
Published: July 2024

Abstract
Objective Our aim was to assess the efficacy of ventriculoperitoneal shunt (VPS) for treating postoperative central nervous system infection (PCNSI) complicated with hydrocephalus and to identify factors associated with treatment failure.
Materials and Methods We conducted a retrospective analysis of PCNSI patients with hydrocephalus treated by VPS at the Department of Neurosurgery, the First Affiliated Hospital, College of Medicine, Zhejiang University, between December 2012 and January 2020. Functional recovery was evaluated during follow-up using the Glasgow Outcome Scale.
Results A total of 29 patients (21 males, 8 females) were enrolled in the study (mean age: 56.4 ± 12.0 years, range: 18.0–77.0 years). Seventeen patients were treated successfully by VPS (58.6%). Among the 11 patients with shunt complications (37.9%), 8 (27.6%) presented with fever, 3 (10.3%) with shunt infection, and 3 (10.3%) with shunt obstruction. Univariate analysis identified low Glasgow Coma Scale (GCS) score (3–8) at the time of VPS and post-treatment fever as predictive of shunt failure.
Conclusion VPS was effective for treating PCNSI complicated with hydrocephalus. However, patients with low GCS score at the time of VPS or fever post-treatment were at greater risk of shunt failure and poor outcome.