bluuebunny/crossref_metadata_2025_split huggingface dataset:
Incidence of Brain Tumors and Its Radiotherapy Treatment Adherence: A Retrospective Cohort Study
Authors: Velarde López Angel Alfonso , Mutic Sasa , de Falla Vicky 
Published: July 2024

PURPOSE According to Global Cancer Statistics in 2022, there were 321,731 new cases of brain and CNS cancers diagnosed, with an age-standardized incidence rate (ASR) for brain and CNS cancers of 3.5 per 100,000 population, from which 248,500 were cancer-related deaths worldwide and have been found to be in the top ten causes of death. Radiosurgery is used to treat brain tumors with remarkable precision and is a safe option for patients also with brain metastases. In Guatemala Radiation therapy is a national priority, because of the 9,800 patients requiring radiation therapy, only 50% receive radiation therapy, and radiosurgery for brain tumors are far from starting for the underserved patients with cancer. Therefore, we aim to determine the incidence of brain tumors and its radiotherapy adherence for patients attending the only comprehensive cancer center (LIGA-Incan). METHODS A retrospective study was conducted to estimate the ASR of brain tumors from 475 patients diagnosed during the years 2006 to 2020 of age 15 years or older. A comparison was established among men(n=106) and women (n=106) who underwent radiotherapy. Descriptive analysis was applied to the variables age, radiotherapy adherence, basis for diagnosis and tumor stage. RESULTS There were 475 patients with CNS tumors of malignant diagnosis, from which 89.76% and 90.91% was based on the histology of the primary tumor in women and men respectively. The overall ASR was 3.90 per 100,000 person-years. Glioblastoma 78 (34.51%) and 55 (25.0%), Astrocytoma 59 (26.11%) and 59 (26.82%), Oligodendroglioma 23 (10.18%) and 30 (13.64%) in women and men respectively. Median age was 44 years for women and 42 for men. Radiotherapy was started in 212(44.63%), from which 106 were women, and radiotherapy adherence completed in 101(47.64%), from which 52(49.06%) were women. Staging was available only for 11 patients (1 patient in stage I, 3 in stage II, 4 in stage III and 3 in stage IV). CONCLUSION Brain tumors are receiving conventional radiotherapy. Therefore, efforts are needed for cooperation that can fruitfully fund the establishment of equipment of radiosurgery for the underserved patients of Guatemala with brain tumors.
Leveraging Implementation Science to Optimize Strategies for Cancer Control in Mexico and Latin America
Authors: Fernandez Maria , Saldaña Karla Unger , Lajous Martin , Potter Michael , Millett Mary-Louise E. , Ibarra Leticia Torres , Chavez Cesar Rodriguez , Duque Erika Mendoza , Balasubramanian Bijal 
Published: July 2024

PURPOSE
Coordinated efforts to bridge cancer control research and practice in Latin America are desperately needed to advance global cancer control equity. Although implementation science applied to this issue is growing in low- and middle- income countries (LMICs), major gaps remain. The purpose of the effort described below was to establish the Leveraging Implementation Science to Optimize Strategies (LISTOS) for Cancer Control Center to advance equitable uptake, use, and sustainment of effective cancer control interventions in Mexico and Latin America by strengthening implementation research and capacity.

METHODS
A transdisciplinary team of investigators in Mexico and the U.S. engaged researchers, and community and stakeholder partners to identify priorities for advancing cancer control through implementation science in Latin America. Supported by the National Cancer Institute’s Global Implementation Science for Equitable Cancer Control initiative, LISTOS was established. The goal is to bridge critical gaps in cancer control by enhancing implementation research capacity and conducting impactful research to promote equitable uptake, utilization, and sustainability of effective cancer control interventions. Rooted in the concept of readiness (“listos” in Spanish), the center focuses on preparing organizations and research teams to optimize the implementation of evidence-based cancer control interventions.

RESULTS
LISTOS encompasses two subthemes: 1) adapting EBIs and implementation strategies to align with diverse populations and settings, and, 2) developing strategies to enhance and expedite the adoption, integration, scale-up, and sustainability of EBIs. The team planned two initial studies to tackle implementation challenges related to adaptation and implementation of colorectal cancer screening in primary care and implementation of integrated care for timely diagnosis of breast cancer. Breast cancer and colorectal cancer are among the most burdensome cancers in Mexico, and preventive and early detection interventions that can greatly improve their control.

CONCLUSION
LISTOS endeavors to drive significant advancements in cancer control implementation science, ultimately leading to improved cancer outcomes and reduced disparities in the region.
Previous Coronavirus Disease-2019 Infection and Lung Mechanics in Surgical Patients: A Hospital Registry Study
Authors: Suleiman Aiman , Munoz-Acuna Ricardo , Redaelli Simone , Ahrens Elena , Tartler Tim M. , Ashrafian Sarah , Hashish May M. , Santarisi Abeer , Chen Guanqing , Riedel Stefan , Talmor Daniel , Baedorf Kassis Elias N. , Schaefer Maximilian S. , Goodspeed Valerie 
Published: July 2024

BACKGROUND:
Long-term pulmonary complications have been reported after a coronavirus disease-2019 (COVID-19). We hypothesized that a history of COVID-19 is associated with a measurable decrease in baseline respiratory system compliance in patients undergoing general anesthesia.

METHODS:
In this hospital registry study, we included adult patients undergoing general anesthesia between January 2020 and March 2022 at a tertiary health care network in Massachusetts. We excluded patients with an American Society of Anesthesiologists physical status >IV, laryngoscopic surgeries, and patients who arrived intubated. The primary exposure was a history of COVID-19. The primary outcome was baseline respiratory system compliance (mL/cmH2O). Effects of severity of infection, surges (Alpha1, Alpha2, Delta, and Omicron), patient demographics, and time between infection and assessment of compliance were investigated.

RESULTS:
A total of 19,921 patients were included. Approximately 1386 (7.0%) patients had a history of COVID-19. A history of COVID-19 at any time before surgery was associated with a measurably lower baseline respiratory system compliance (ratio of meansadj = 0.96; 95% confidence interval [CI], 0.94–0.97; P < .001; adjusted compliance difference: −1.6 mL/cmH2O). The association was more pronounced in patients with a severe form of COVID-19 (ratio of meansadj = 0.95; 95% CI, 0.90–0.99; P = .02, adjusted compliance difference: −2 mL/cmH2O). Alpha1, Alpha2, and Delta surges, but not Omicron, led to a lower baseline respiratory system compliance (P < .001, P = .02, and P < .001). The Delta surge effect was magnified in Hispanic ethnicity (P-for-interaction = 0.003; ratio of meansadj = 0.83; 95% CI, 0.74–0.93; P = .001; adjusted compliance difference: −4.6 mL/cmH2O).

CONCLUSIONS:
A history of COVID-19 infection during Alpha1, Alpha2, and Delta surges was associated with a measurably lower baseline respiratory system compliance.
Medical Malpractice in Neurosurgery: An Analysis of Claims in the Netherlands
Authors: Dronkers Wouter J. , Buis Dennis R. , Amelink Quirine J. M. A. , Bouma Gert-Joan , Peul Wilco C. , Vandertop W. Peter , Broekman Marike L. D. , Hendriks Aart C. , Dirven Clemens M. F. , Spoor Jochem K. H. 
Published: July 2024

BACKGROUND AND OBJECTIVES:
Studying malpractice claims is important to improve quality of health care and patient safety and to educate the individual healthcare providers. The objective of this study was to describe characteristics of neurosurgical claims in the Netherlands.

METHODS:
A nationwide retrospective observational study of neurosurgery-related claims closed by Centramed and MediRisk, 2 major insurance companies in the Netherlands, was performed. Relevant data, including type of neurosurgical pathology, theme and category of the claim, type and severity of injury, outcome, and financial burden, were extracted from anonymized claim files. The estimated annual risk was used to determine the risk for claims by adjusting for the number of annually practicing neurosurgeons in the Netherlands.

RESULTS:
A total of 388 claims against neurosurgeons were closed between 2007 and 2021. Liability was denied in a slight majority of claims (n = 230; 59%). The total burden during this period was €6 165 000 (amount paid out to patients: €5 497 000). The estimated annual risk per Dutch neurosurgeon for a claim was 15.5%, meaning 1 claim per 6.5 years. The case-level analysis of 238 available anonymized claims revealed that most claims were related to spinal pathology (81.5%), followed by cranial pathology (10.9%) and peripheral nerve (7.6%). The motivations for filing claims were mostly related to alleged surgical (56.3%) or diagnostic errors (22.3%). Most of these claims were denied (151/238; 63.4%), and fewer were settled (42/238; 17.6%), sustained (31/238; 13.0%), or closed without final decision (14/238; 5.9%).

CONCLUSION:
Neurosurgery-related malpractice claims primarily involved spinal pathology and were mostly related to alleged treatment errors. Most claims did not result in compensation because there seemed to be no liability or culpable injury. However, the annual risk for a claim for Dutch neurosurgeons is considerable.
The Transmission of Economic Shocks in Multidivisional Organizations: An Empirical Analysis of the Global Retail Industry
Authors: Sohl Timo , McCann Brian T. , Vroom Govert 
Published: July 2024

Capital allocation research has long argued that divisions of multidivisional organizations may be relatively advantaged compared with standalone firms when external capital markets are less efficient. As a complement to this literature that largely focuses on deficiencies in the supply of external capital, we theorize about the effects of disruptions to internal capital markets. More specifically, we explore the impact of parent-level financial shocks on the growth of divisions. We first argue that the effects of a crisis in a parent country disrupt the supply of internal capital available to foreign divisions, resulting in significantly reduced asset growth in these divisions. Next, we offer an initial step toward developing comprehensive understanding of the contextual influences that may intensify or attenuate the effect of shocks by theorizing a broad set of moderators that consider the parent level, parent-division linkages, and the division level within multidivisional organizations. Analyses of 1,968 geographic divisions of multinational retailers across 92 host countries show that effects of parent financial crises on division investment depend on factors influencing the degree of parent exposure, shock transmission, and division adaptability. Funding: This work was supported by the Ministerio de Ciencia, Innovación y Universidades [Grants PID2020-115660GB-I00 and RYC2022-036434-I]. Supplemental Material: The online appendix is available at https://doi.org/10.1287/orsc.2022.16521 .
Sexual anxiety mediate relationship between sexual schemas and body image with sexual function in Iranian women
Authors: Yousefi Afrashteh Majid , Blouri Rojan , Morovati Zekrollah 
Published: July 2024

Background
Sexual function is one of the most critical challenges in human society, especially among women. The problems associated with sexual function are significantly ambiguous in a society like Iran. This study investigated the mediating role of sexual anxiety in relationship between sexual schemas and body image with female sexual function.

Method
The research method was correlational and specifically path analysis. The statistical population included women aged 25–45 in Rasht, Iran, 2021. 365 women were selected using Cochran’s formula and the convenience sampling method. The Female Sexual Function Index (FSFI), Sexual Self-Schema Scale for Women (SSSS), Body Image Scale (BIS), and Multidimensional Sexual Self-Concept Questionnaire (MSQ) were used for data collection. For data analysis, SPSS-26 and LISREL 10.2 software were used.

Results
Descriptive data analysis showed that mean and standard deviation were for further passionate-romantic schema 22.96 and 4.83, open-direct schema 27.64 and 5.09, embarrassed-conservative 20.93 and 4.61, body image 128.96 and 27.35, sexual anxiety 13.13 and 3.91 and sexual function 49.83 and 8.67. According to the results of path analysis, passionate-romantic (β = 0.51), explicit-comfortable (β = 0.27), shy-conservative (β = -0.59), and body image (β = -0.62) schemas showed a significant relationship with sexual function. Sexual function anxiety as a mediating variable also had a significant role (β = -0.41) in female sexual function.

Conclusion
Sexual function anxiety, negative body image, and negative sexual schema negatively affect women’s sexual function, and positive sexual schemas and body image positively affect sexual function anxiety.
Measuring social norms related to child marriage among married women and men in Niger
Authors: Sripad Pooja , Pinchoff Jessie , Dadi Chaibou , Dougherty Leanne 
Published: July 2024

Background
Child marriage remains prevalent in the Sahel region. Pervasive norms regarding child marriage, and sexual behavior persist. We explored norms from multiple perspectives to strengthen interventions aimed at delaying age at marriage.

Methods
This study analyzed a cross-sectional household survey conducted in Niger in 2022 with women aged 15–49 (n = 2,726) and a subset of their male household members aged 15–59 (n = 1,136). Separate logistic regression models assessed factors associated with three descriptive (e.g., perception of what others do) and injunctive (e.g., perception of a group’s approval or disapproval) normative outcomes related to practices that support marriage as soon as a girl reaches puberty and beliefs related to premarital sex.

Results
Our study found a greater proportion of men described early marriage as protective from the fear of socially induced ruined marital prospects for women (70% vs. 64%), while women expressed its protection from being harassed (62% compared to 42%). The injunctive norm outcome that “my neighbors think that one should marry off one’s daughter as soon as she reaches puberty” was significantly associated with the belief that child marriage was protective for females among women (OR = 4.49; 95% CI 3.13. 5.50) and men (OR = 8.21; 95% CI 5.88, 11.45).

Conclusions
Programs addressing child marriage should consider both male and female perspectives to address differences and foster an environment where communities and families shift norms to delay early marriage.
First-line antiretroviral therapy initiation for newly diagnosed people with HIV in the Netherlands: A retrospective analysis from 2016 to 2020
Authors: Oosterhof Piter , Wit Ferdinand W. N. M. , van Luin Matthijs , van der Valk Marc , Brinkman Kees , Burger David M. 
Published: July 2024

Introduction
HIV treating physicians in the Netherlands follow the guidelines of the Department of Health and Human Services (DHHS). Most of these recommended initial regimens are single-tablet regimens (STRs), which incur higher costs. By the end of 2017, generic NRTI backbones had become widely available, offering a potentially cheaper multi-tablet regimen. This study aimed to evaluate guideline compliance in people with HIV who started antiretroviral therapy (ART), the uptake of generic multi-tablet regimens (gMTRs), and associated medication costs.

Methods
This retrospective cohort study used data from the Dutch HIV Monitoring Foundation to determine the proportion of treatment-naïve people entering care who initiated ART according to the DHHS and type of ART regimens prescribed between January 2016 and December 2020. We analyzed ART prescriptions, both at the national level and per individual HIV treatment centers. We calculated the monthly ART costs based on Dutch medicine prices listed on www.medicijnkosten.nl for each calendar year.

Results
In 2016, an integrase inhibitor-containing regimen was initiated in 77.3% which increased to 87.8% in 2020. The compliance rate to DHHS-recommended initial regimens ranged from 82.8% in 2016 to 90.9% in 2020. Most patients received single-tablet regimens, 81.3% in 2016 to 60.3% in 2020. After the introduction the gMTRs showed a steady increase from 17.8% in 2018 to 37.8% in 2020. The cost of the first-line regimen per patient decreased by 22.9% in 2020 compared with 2017. The decrease was larger in centers where treatment-naïve individuals with HIV were preferentially initiated on a gMTR.

Conclusions
There was a high compliance to the “DHHS-recommended initial regimens for most people with HIV” in the Netherlands. Most people who initiated ART received STRs, although the percentage of people who started on STRs gradually decreased over time. The use of gMTRs increased over time and was associated with lower medication costs.
A “Mulher Negra” confronta o “Mito Fundador”: heresias ensaísticas em Lélia Gonzalez e Marilena Chaui
Authors: Pires Maria Raquel Gomes Maia 
Published: July 2024

Resumo: No presente artigo, discutimos as contribuições do gênero ensaio ao pensamento crítico feminista, identificadas nos procedimentos formais da linguagem nos textos de Lélia Gonzalez e de Marilena Chaui acerca da sociedade brasileira. Questionamos de que maneira as características do ensaio potencializam a crítica ao sexismo, racismo e autoritarismo nas concepções da “Mulher negra”, em Gonzalez, num confronto imaginário com o “Mito Fundador”, em Chaui. Objetivamos localizar na escrita das autoras os artifícios característicos do ensaio, mobilizados para estimular reflexões críticas nas leitoras. Em meio ao embate da “Mulher Negra” com o “Mito Fundador”, apostamos nos sentidos erráticos do ensaio diante do discurso dogmático que violenta o corpo negro feminino.
Palavras-chave: Lélia Gonzalez; Feminismo; Ensaio; Linguagem; Teoria Crítica
The “Black Woman” confronts the “Founding Myth”: essay heresies in Lélia Gonzalez and Marilena Chaui
Abstract: In this article, we discuss the contributions of the essay genre to feminist critical thinking, identified in the formal procedures of language in the texts of Lélia Gonzalez and Marilena Chaui regarding Brazilian society. We question how the characteristics of the essay strengthen criticism of sexism, racism and authoritarianism in the conceptions of the “Black Woman”, in Gonzalez, in an imaginary confrontation with the “Founding Myth” in Chaui. We aimed to locate, in the authors’ writing, the characteristic devices of the essay, mobilized to stimulate critical reflections in the readers. In the midst of the clash between the “Black Woman” and the “Founding Myth”, we bet on the erratic meanings of the essay faced with the dogmatic discourse that violates the female Black body.
Keywords: Lélia Gonzalez; Feminism; Essay; Language; Critical Theory
La “Mujer Negra” se enfrenta al “Mito Fundador”: herejías ensayísticas en Lélia González y Marilena Chaui
Resumen: En este artículo, discutimos las contribuciones del género ensayo al pensamiento crítico feminista, identificadas en los procedimientos formales del lenguaje en los textos de Lélia Gonzalez y Marilena Chaui sobre la sociedad brasileña. Nos preguntamos cómo las características del ensayo potencian la crítica al sexismo, racismo y autoritarismo en las concepciones de la “Mujer Negra”, en González, en un enfrentamiento imaginario con el “Mito Fundador”, en Chaui. Nuestro objetivo es ubicar en la escritura de las autoras los dispositivos característicos del ensayo, movilizados para estimular reflexiones críticas en las lectoras. En medio del choque de la “Mujer Negra” con el “Mito Fundador”, apostamos por los significados erráticos del ensayo frente al discurso dogmático que violenta el cuerpo negro femenino.
Palabras clave: Lélia Gonzalez; Feminismo; Ensayo; Lenguaje; Teoría Crítica

Data de registro: 14/03/2023
Data de aceite: 10/07/2023
Blood pressure and heart rate variability to assess autonomic response to an acute bout of high intensity interval exercise in healthy young adults
Authors: Waghmare Saniya , Whitaker‐Hilbig Alicen A. , Chertoff Mark , Billinger Sandra A. 
Published: July 2024

AbstractAutonomic nervous system (ANS) activity causes acute variations in blood pressure (BP) and heart rate (HR). These systems are challenged during high intensity interval exercise (HIIE). However, BP variability (BPV) and HR variability (HRV) response to HIIE is unknown. We characterized BPV and HRV during an acute HIIE bout using spectral low frequency [LF] and high frequency [HF] domains. We hypothesized that BPV would increase and HRV would decrease during high‐intensity and active‐recovery of HIIE compared to baseline [BL] and BPV would reduce and HRV would increase during cool down, post‐HIIE, and 30 min post‐HIIE compared to BL. HIIE involved 10 min of alternating high‐intensity and active‐recovery (approximately 70% and 10% of Wattmax) on a recumbent stepper. We did a secondary analysis on 23 datasets. The participants were 25 ± 1.5 years, 48% females. Our results showed high‐intensity BPV LF was not significantly different from BL while HF increased. HRV LF and HF decreased compared to BL. During active‐recovery, LF and HF for BPV and HRV increased greater than high‐intensity. HRV LF and HF returned to BL after 30 min of recovery, whereas BPV HF was higher compared to BL. The rapid switching during HIIE uniquely modulates cardiovascular and ANS.
Rational points on a class of cubic hypersurfaces
Authors: Jiang Yujiao , Wen Tingting , Zhao Wenjia 
Published: July 2024

Abstract
Let

r
⩾
3

r\geqslant 3

be an integer and 𝑄 any positive definite quadratic form in 𝑟 variables.
We establish asymptotic formulae with power-saving error terms for the number of rational points of bounded height on singular hypersurfaces

S
Q

S_{Q}

defined by

x
3

=

Q
⁢

(

y
1

,
…
,

y
r

)

⁢
z

x^{3}=Q(y_{1},\dots,y_{r})z

.
This confirms Manin’s conjecture for any

S
Q

S_{Q}

.
Our proof is based on analytic methods, and uses some estimates for character sums and moments of 𝐿-functions.
In particular, one of the ingredients is Siegel’s mass formula in the argument for the case

r
=
3

r=3

.
Examining the impact of foreign language anxiety and language contact on oral proficiency: a study of Chinese as a second language learners
Authors: Gong Yang (Frank) , Chen Mo , An Ziyi 
Published: July 2024

Abstract
This study addresses gaps in the existing literature on foreign language anxiety (FLA) by examining its impact on the oral proficiency of Chinese as a second language (CSL) learners. Unlike previous research, this investigation includes less commonly taught languages and considers the role of language contact as a mediating variable. Using structural equation modelling (SEM), we reveal that (1) CSL learning anxiety negatively affects CSL oral complexity and fluency in a direct way, but does not influence oral accuracy; (2) language contact affects CSL oral proficiency, with verbal contact having a particular impact on oral fluency; and (3) language contact does not mediate the relationship between CSL learning anxiety and oral proficiency. This study contributes to current theories of FLA in L2 acquisition by highlighting the roles of anxiety in different oral proficiency measurements even though the mediating effect of language contact does not exist.