bluuebunny/crossref_metadata_2025_split huggingface dataset:
Histopathologic and immunohistochemical features of sea urchin granulomas
Authors: Suárez‐Peñaranda Jose Manuel , Vieites Begoña , Del Río Emilo , Ortiz‐Rey Jose Antonio , Antón Iosu 
Published: March 2013

BackgroundParacentrotus lividus is the most common variety of sea urchin in the west coasts of Spain and has commercial value for the alimentary industry. Puncture with the spine of its rigid external skeleton may cause mechanical injury by skin penetration. It causes immediate local symptoms and, in some cases, a delayed reaction occurs in the site of injury, weeks to months later. In this case, persistent, firm, flesh‐colored papules or nodules develop.Material and methodsTwenty‐four biopsies from 21 patients with the diagnosis of sea urchin granuloma were studied, as well the clinical data. Specimens were routinely processed and stained with hematoxylin–eosin and leucocyte common antigen, CD20, CD3, CD4, CD8, CD30, CD68, kappa and lambda.ResultsPatients presented with persistent, single or multiple, nodules or papules, usually located in the hands. They developed from 2 weeks to over 1 year after the injury. Histopathologically, granulomas were present in all but one case. Sarcoidal granulomas were more common than suppurative or necrobiotic granulomas. Immunohistochemistry showed a polymorphous lymphoid inflammatory infiltrate, with T leucocytes predominating in most cases.ConclusionHistopathological examination of sea urchin granulomas shows a non‐specific granulomatous inflammation, in most cases of sarcoidal type. Being aware of the triggering event is necessary for the correct diagnosis.
Cinacalcet effect on polymorphonuclear leucocytes of kidney transplant patients
Authors: Cohen Gerald , Raupachova Jana , Borchhardt Kyra , Hörl Walter H. 
Published: March 2013

AbstractBackgroundPolymorphonuclear leucocytes (PMNLs) play a key role in the nonspecific immune defence. Cinacalcet reduces serum calcium levels in kidney transplant recipients with mineral bone disorder associated with chronic kidney disease. We investigated essential functions of PMNLs of kidney transplant recipients with and without hypercalcaemia and with and without cinacalcet therapy.Subjects and methodsOxidative burst, phagocytosis, apoptosis and intracellular calcium concentrations of PMNLs from normocalcaemic kidney transplant patients without (KT‐NC) or with cinacalcet intake (KT‐NC/CI), hypercalcaemic kidney transplant patients (KT‐HC) and healthy subjects (HS) were investigated.ResultsStimulation of oxidative burst of PMNLs from KT‐HC patients by phorbol‐12‐myristate‐13‐acetate or Escherichia coli was significantly attenuated compared with PMNLs from KT‐NC, KT‐NC/CI and HS. Apoptosis of PMNLs from KT‐HC patients was significantly decreased compared with cells from KT‐NC, KT‐NC/CI and HS. Apoptosis correlated significantly with serum calcium concentrations. Intracellular calcium concentrations and phagocytosis of PMNLs did not differ between groups.ConclusionsOur data indicate that stimulation of PMNL oxidative burst and apoptosis is significantly diminished in kidney transplant patients with hypercalcaemia, while kidney transplant patients with serum calcium levels normalized by cinacalcet have normal PMNL functions despite immunosuppressive therapy.
Management of psychogenic nonepileptic seizures
Authors: LaFrance W. Curt , Reuber Markus , Goldstein Laura H. 
Published: March 2013

SummaryThe International League Against Epilepsy (ILAE)NeuropsychobiologyCommission gave the charge to provide practical guidance for health professionals for the pharmacologic and nonpharmacologic treatment of patients with psychogenic nonepileptic seizures (PNES). Using a consensus review of the literature, an international group of clinician‐researchers in epilepsy, neurology, neuropsychology, and neuropsychiatry evaluated key management approaches forPNES. These included the following: presentation of the diagnosis, early phase treatment, psychological and pharmacologic interventions, and maintenance management. The aim of this report is to provide greater clarity about the range and current evidence base for treatment for patients withPNES, with the intention of improving the care of patients withPNESand patients who developPNESas a comorbidity of epilepsy.
Measuring the Kind of Australia We Want: The Australian National Development Index, the Gross Domestic Product and the Global Movement to Redefine Progress
Authors: Salvaris Mike 
Published: March 2013

AbstractThere is a growing global movement to re‐define progress beyond gross domestic product (GDP) and develop new measures of equitable and sustainable well‐being. GDP's shortcomings as the chief measure of societal progress have been clearly exposed, but it is still widely used in this role, with increasingly adverse consequences. This article examines the lessons from this global movement and the technical and democratic requirements for developing new national progress measures. It focuses on a new Australian project, the Australian National Development Index, which will develop a composite index of national progress and key progress ‘domains’ through a national community engagement process supported by a cross‐disciplinary research program.
The Absorption of Recent Graduates into the Australian Labour Market: Variations by University Attended and Field of Study
Authors: Li Ian W. , Miller Paul W. 
Published: March 2013

AbstractThis study uses data from the 1999 to 2009 Graduate Destination Surveys to investigate the absorption of recent university graduates into the Australian labour market. The results indicate that graduates of the Group of Eight and Australian Technology Network are less likely than graduates of other universities to be employed in jobs that do not require their qualification. No university group, however, has a clear advantage in protecting its graduates from the adverse earnings consequences associated with working in such jobs. Field of study plays an important role in determining both whether graduates work in occupations that require their qualification and earnings.
How Well Do Australian Home‐Owners Know the Value of Their Home?
Authors: Melser Daniel 
Published: March 2013

AbstractOwners' estimates of the value of their home are widely used in research and form the basis of much of our understanding of household wealth. But are these estimates accurate? Using hedonic methods and data from the Household, Income, and Labour Dynamics in Australia Survey, I investigate this for Australian home‐owners. The findings indicate that owners over‐estimate their home's value by around 2.5 per cent or $100 billion economy‐wide. Importantly, the extent of mis‐estimation depends upon the age of the home‐owner and the size of the home. Thus, some caution needs to be exercised when comparing reported housing wealth across groups, as part of these differences may reflect differential estimation errors.
The Foundations of Well‐Being
Authors: Moss Jeremy 
Published: March 2013

AbstractThis article considers the philosophical foundations of preference‐based and capability approaches to well‐being. I argue that standard preference‐based approaches face difficulties in providing a satisfactory account of well‐being and that the capability approach, developed by Amartya Sen, offers a superior account. In particular, I argue that subjective preference accounts of well‐being are philosophically difficult to sustain and utilise in a public policy context.
The Race to Be the Perfect Nation
Authors: Sonrexa Juhi , Moodie Rob 
Published: March 2013

AbstractIn the last 2 decades, there has been a remarkable proliferation of indices of well‐being which assess and rank country performance according to a diverse range of environmental, political, health, social or economic measures. This growth is a clear sign of their political importance, popular appeal and operational relevance in decision‐making. This article discusses questions about the validity and scope of summary indices of well‐being, as well as explores the relevance of country rankings. Acknowledging that these measures are imperfect, but that they may be the best measures we have, this article discusses how these composite indicators can be improved and how policy‐makers should be using them.
Modified Proximal Perineal Urethrostomy Technique for Treatment of Urethral Stricture in Goats
Authors: Tobias Karen M. , van Amstel Sarel R. 
Published: March 2013

AbstractObjectiveTo report a modified procedure for perineal urethrostomy (PU) in goats.Study DesignCase series.AnimalsAdult castrated male pet goats (n = 11) that had recurrence of urinary tract obstruction after one or more surgical procedures for obstructive urolithiasis.MethodsMedical records (May 2008–February 2011) of goats that had a modified proximal PU were reviewed for history, signalment, and intraoperative and postoperative complications. Follow up was obtained through clinical examination or by telephone interview of owners or referring veterinarians.ResultsTen goats survived to discharge. Postoperative complications included hemorrhage (n = 7), misdirected urine stream (3), obstructive urolithiasis (2), and bladder atony, dysuria, dehiscence, or delayed healing (1 each). One goat died acutely 15 hours after surgery from peritonitis, pleuritis, hemorrhagic cystitis, and hepatic lipidosis, and 1 goat was euthanatized 14 months after surgery because of renal failure and persistent cystitis. Urethrostomy sites were patent and functional in 9 goats available for long‐term follow‐up (>12 months).ConclusionsTransection of penile body attachments from the pelvis and careful mucocutaneous apposition may decrease the risk of postoperative urethral stricture formation in goats after PU. Hemorrhage is common after the procedure but does not affect clinical outcome.
The International Labour Review and the ILO: Milestones in a shared history
Authors: BOLLÉ Patrick 
Published: March 2013

Abstract.As the ILO is approaching its 100th anniversary, so is the International Labour Review. By way of introduction to this retrospective Special Supplement, which reproduces a number of articles written for the Review by winners of the Nobel Peace Prize or the Nobel Prize for economics, the author looks back at the journal's history, recalling its early days since the 1919 Treaty of Versailles, its subsequent development, broadening international readership and adaptation to the digital age. He concludes with a brief presentation of the selected authors and their work, which is considered in the context of current research and debate.
Synthesis and Optimization of the Production of Millimeter‐Sized Hydroxyapatite Single Crystals by Cl−–OH− Ion Exchange
Authors: García‐Tuñon Esther , Franco Jaime , Eslava Salvador , Bhakhri Vineet , Saiz Eduardo , Giuliani Finn , Guitián Francisco 
Published: March 2013

Millimeter‐sized hydroxyapatite (HA) single crystals were synthesized from chlorapatite (ClAp) crystals via the ionic exchange of Cl− for OH− at high temperature. X‐ray diffraction, Fourier‐transform infrared spectroscopy, and chloride content measurements were used to follow the progress of this conversion, and to assess the effect of the experimental conditions (temperature, time, and atmosphere). Cl−→OH− exchange took place homogeneously and was enhanced by firing in wet air. After firing at 1425°C for 2 h 92% of the Cl− ions were exchanged by OH− while maintaining crystal integrity. Temperatures above 1450°C damaged the surface of the crystals, destroying the hexagonal habit at 1500°C. The composition of these apatite crystals was close to bone mineral content. Their nanoindentation hardness (8.7 ± 1.0 GPa) and elastic nanoindentation modulus (120 ± 10 GPa) were similar to those of the starting ClAp (6.6 ± 1.5 GPa, and 110 ± 15 GPa, respectively). However, their average flexural strength was ~25% lower due to the formation of defects during the thermal treatments.
Higher order language competence and adolescent mental health
Authors: Cohen Nancy J. , Farnia Fataneh , Im‐Bolter Nancie 
Published: March 2013

BackgroundClinic and community‐based epidemiological studies have shown an association between child psychopathology and language impairment. The demands on language for social and academic adjustment shift dramatically during adolescence and the ability to understand the nonliteral meaning in language represented by higher order language becomes essential.Objectives: This article reports on the association between difficulties in higher order language skills, reading, cognition, and social‐emotional adjustment in adolescents.Method: 144 clinic‐referred and 186 comparison youth aged 12–18 years were administered a battery of standardized tests of intelligence, working memory, structural and higher order language, and reading achievement. Parent ratings on the Child Behavior Checklist were used as a measure of severity of social‐emotional problems.Results: Clinic‐referred youth scored significantly lower than comparison youth on measures of structural and higher order language, working memory, and reading. Of the clinic‐referred youth, 45% had some type of higher order language impairment, whereas this was the case for 15% of youth in the comparison group. Lower levels of nonverbal ability and working memory as well as lower level of mothers’ education were associated with greater risk of having higher order language impairment.Conclusions: Findings have implications for practitioners’ seeking to understand and treat adolescents since therapeutic techniques rely on skills where higher order language is at play including the ability to discuss opinions flexibly and to weigh interpretations. Therapists must be aware that there are areas that have potential for miscommunication with some adolescents and where inaccurate inferences may be made about their behavior. Furthermore, educators must consider resources for youth who may increasingly struggle in high school because of such difficulties.
Research Review: Social motivation and oxytocin in autism – implications for joint attention development and intervention
Authors: Stavropoulos Katherine K. M. , Carver Leslie J. 
Published: March 2013

Background and scopeThe social motivation hypothesis (SMH) suggests that individuals with autism spectrum disorders (ASD) are less intrinsically rewarded by social stimuli than their neurotypical peers. This difference in social motivation has been posited as a factor contributing to social deficits in ASD. Social motivation is thought to involve the neuropeptide oxytocin. Here, we review the evidence for oxytocin effects in ASD, and discuss its potential role in one important social cognitive behavior.MethodsSystematic searches were conducted using the PsychINFO and MEDLINE databases and the search terms ‘oxytocin’ and ‘autism’; the same databases were used for separate searches for ‘joint attention’, ‘intervention’, and ‘autism’, using the same inclusion criteria as an earlier 2011 review but updating it for the period 2010 to October 2012.FindingsSeveral studies suggest that giving oxytocin to both individuals with ASD and neurotypical individuals can enhance performance on social cognitive tasks. Studies that have attempted to intervene in joint attention in ASD suggest that social motivation may be a particular obstacle to lasting effects.ConclusionsThe review of the evidence for the SMH suggests a potential role for oxytocin in social motivation deficits in ASD. Because of its importance for later communicative and social development, the focus here is on implications of oxytocin and social motivation in the development of and interventions in joint attention. Joint attention is a central impairment in ASD, and as a result is the focus of several behavioral interventions. In describing this previous research on joint attention interventions in ASD, we pay particular attention to problems encountered in such studies, and propose ways that oxytocin may facilitate behavioral intervention in this area. For future research, integrating behavioral and pharmacological interventions (oxytocin administration) would be a worthwhile experimental direction to improve understanding of the role of oxytocin in ASD and help optimize outcomes for children with ASD.
Challenges and a response strategy for the development of nursing in China: a descriptive and quantitative analysis
Authors: Wang Yingqiang , Wei Shiyou , Li Youping , Deng Shaolin , Luo Qianqian , Li Yan 
Published: March 2013

AbstractObjectiveTo assess the challenges to and provide a response strategy for the development of nursing and make suggestions for promoting the nursing discipline, platform, and talent teams based on current best available evidence.MethodsWe searched CNKI(China National Knowledge Infrastructure), VIP information(Chinese Scientific Journals database), CBM(Chinese Biomedical Literature database), and Web sites of the World Health Organization, International Council of Nurses, World Bank, the Ministry of Health and the Ministry of Education of China, and relevant schools in China. Data analyses were performed using SPSS 13.0.ResultsWe identified 886 nursing schools in China in 2012. Results showed that 38,212 nursing students were enrolled in universities or independent colleges and 130,837 nursing student were enrolled in colleges or senior vocational schools. The doctor‐to‐nurse ratio was 1:0.9 in 2010. The actual demand for doctors was 2.6 million, whereas the nursing shortage was approximately 346,000. Nurses aged ≤35 years accounted for 50% of the total. A total of 64% to 69% of nurses had primary professional titles; fewer than 2.5% of those had advanced titles. The training costs for one doctor or one nurse in China was only two‐fifths that in India and one‐fifth to one‐fourth that in sub‐Saharan Africa. To date, only 30.1% of disaster nursing studies in China provided research data; 30.6% were related to clinical experience and 38.3% were reviews.ConclusionsEducation and health systems need to be extensively reformed. It is necessary to train nursing students with core competencies using transformative learning. It is necessary to update textbooks and teaching methods, and funding should be appropriately increased. Nursing should co‐operate with other disciplines, and apply evidence‐based nursing methods to improve the quality of healthcare services and patient satisfaction.
Pediatric off‐label drug use in China: risk factors and management strategies
Authors: Zhang Lingli , Li Youping , Liu Yi , Zeng Linan , Hu Die , Huang Liang , Chen Min , Lv Juan , Yang Chunsong 
Published: March 2013

AbstractObjectiveTo analyze the risk factors of pediatric off‐label drug use, and propose management strategies for policy making of the pediatric off‐label drug use in China.Methods(i) We applied stratified random sampling to select recipes of children aged 0 to 18 years in pediatric clinics and wards of the West China Second University Hospital in 2010. (ii) All included prescriptions were categorized as off‐label use or on‐label use, according to the latest package insert licensed by the State Food and Drug Administration. (iii) Risk factors and the weights were calculated using logistic regression. (iv) The correlation between risk factors and the different kinds of off‐label prescriptions was presented using adjusted odds ratio, and the impact of the risk factors was measured using standardized partial regression coefficient. (v) SPSS 16.0 was used for statistic analysis. (vi) From the perspective of the medical institutions, pharmaceutical enterprises, professional institutions, and the public, we combined the results of the Evidence‐based research on the policy of the off‐label drug use in 15 countries and the results of risk factor analysis, in order to propose management strategies for the policy making of pediatric off‐label drug use in China.Results(i) Using the method of sampling, we received 2640 recipes from outpatients and 14,374 prescriptions from 749 inpatients. (ii) The neonates (0 to 27 days) had higher risk in off‐label drug use than the other three children age groups. (iii) The dermatological medicines (D), nervous system medicines (N), traditional Chinese medicines, and respiratory drugs (R) were high‐risk off‐label medicines whose labels should be updated more frequently. (iv) The great factors of off‐label drug use are those influence health status and relate to health services (ICD‐10:Z00‐Z99) (mainly in the clinic of child care and growth development, and in the ward of chemotherapy). (v) Off‐label drug use in the ward was 4.4 times than that in clinic service (P < 0.001), which suggested that off‐label drug use in the ward may be a key point of the management of medical institutions. (vi) The risk of off‐label essential drug use was 1.67 times than that of non‐essential drug use. (vii) The risk of off‐label Rx drug use was 3.2% higher than that of OTC (Over‐The‐Counter) drug use, without a significant difference.Conclusions(i) A management guideline for off‐label drug use is urgently needed, with which we can guide medical institutions to establish the management regulations of off‐label drug use. (ii) Pediatric clinical research should be promoted actively, and pharmaceutical enterprises should be encouraged to completely provide pediatric drug information. (iv) Academic organizations should be invited to join in for best professional drug use. (v) Pediatric patients and their families should receive the education on rational drug use.
Geriatric Syndromes and Incident Disability in Older Women: Results from the Women's Health Initiative Observational Study
Authors: Rosso Andrea L. , Eaton Charles B. , Wallace Robert , Gold Rachel , Stefanick Marcia L. , Ockene Judith K. , Curb J. David , Michael Yvonne L. 
Published: March 2013

ObjectivesTo determine how the number of geriatric syndromes is associated with incident disability in community‐based populations of older adults.DesignLongitudinal analysis from the Women's Health Initiative Observational Study (WHI‐OS).SettingCommunity.ParticipantsTwenty‐nine thousand five hundred forty‐four women aged 65 and older enrolled in the WHI‐OS and free of disability in activities of daily living (ADLs) at baseline.MeasurementsGeriatric syndromes (high depressive symptoms, dizziness, falls, hearing or visual impairment, osteoporosis, polypharmacy, syncope, sleep disturbance, and urinary incontinence) were self‐reported at baseline and 3‐year follow‐up. Disability was defined as dependence in any ADL and was assessed at baseline and follow‐up. Chronic diseases were measured according to a modified Charlson Index.ResultsGeriatric syndromes were common in this population of women; 76.3% had at least one syndrome at baseline. Greater number of geriatric syndromes at baseline was significantly associated with greater risk of incident ADL disability at follow‐up (P ≤ .001). Adjusted risk ratios were 1.21 (95% confidence interval (CI) = 0.78–1.87) for a single syndrome and 6.64 (95% CI = 4.15–10.62) for five or more syndromes compared with no syndromes. These results were only slightly attenuated after adjustment for number of chronic diseases or pain.ConclusionGeriatric syndromes are significantly associated with onset of disability in older women; this association is not simply a result of chronic disease or pain. A better understanding of how these conditions contribute to disablement is needed. Geriatric syndrome assessment should be considered along with chronic disease management in the prevention of disability in older women.