bluuebunny/crossref_metadata_2025_split huggingface dataset:
Detection of Resistant Escherichia coli During Meat Processing in Food Establishments
Authors: Dančová Nikola , Regecová Ivana , Gregová Gabriela , Király Ján , Szabóová Tatiana 
Published: June 2024

Abstract
Meat is an important food source, the nutritional composition of which, in conjunction with its desirable taste, positively affects human development and health. From a veterinary point of view, meat obtained from food-producing animals is also a potential reservoir for foodborne pathogens, including Escherichia coli. The prevalence and spread of antibiotic-resistant E. coli represent a threat to public health. For these reasons, the aim of this work was to identify the isolates obtained from food processing plants and to confirm the presence of E. coli species based on phenotypic and genotypic expression. The susceptibility of the investigated strains to antibiotics and their combinations was determined using the modified microdilution method. Dominant resistance was detected against ampilicin, tetracycline, cotrimoxazole, ampilicin + sulbactam, ciprofloxacin, and cefuroxime. Resistance to ertapenem, cefotaxime, tigecycline, and ceftazidime was also detected sporadically. Frequent mechanism responsible for resistance was generated an incomplete fluoroquinolone resistance induced by mutation and penicillinase with low enzyme expression. The occurrence of multidrug-resistant strains was also detected. Selected E. coli isolates were subjected to detection of genes encoding resistance to tetracyclines (tetA and tetB) and quinolones (qnrA, qnrB, and qnrS) by PCR. The tetA gene was confirmed in 68 % of the isolates, and the tetB gene in one isolate. The prevalence of the qnrA gene was found to be 29 % in the examined isolates. Two isolates showed the presence of the qnrS gene. The qnrB gene, as well as a combination of the qnrA and qnrB genes, was detected in one isolate.
Canine Babesiosis and Therapy Options – A Review
Authors: Malinovská Zuzana 
Published: June 2024

Abstract
Babesiosis is a disease caused by intraerythrocytic protozoal parasites, which occurs in animals and humans. In dogs, babesiosis can be caused by eight species of Babesia gene: i.e., B. canis, B. rossi, B. vogeli, B. coco, B. gibsoni, B. conradae, B., and B. negevi, which are bound to certain geographical areas. The disease has a focal nature and its transmission depends mainly on vectors, which are ticks of various species. Due to transstadial, and transovarial transmission, babesiosis is able to persist in natural foci in several generations of ticks, even without the presence of a susceptible host. Typical clinical signs associated with canine babesiosis are: fever, apathy, weakness, pale mucous membranes, icterus and hemoglobinuria. The disease can have an acute or peracute course, and subclinical and subacute infections have also been described. The clinical manifestations of babesiosis may vary depending on the particular species and strains, and their specific virulence, but also depending on factors that determine the host’s response to infection, such as age, individual immune status, and the presence of concurrent infections or other diseases. Medicines, from the group of antiprotozoans, a selected group of antibiotics, or their combinations are used for therapy. There are differences in the therapy of babesiosis depending on the Babesia species, the animal is often cured of the acute phase, but the parasite remains in the organism.
Development and empirical testing of a questionnaire-based algorithm to evaluate physical and psychosocial health status in performing artists / Entwicklung und empirische Testung eines fragebogenbasierten Algorithmus zur Erhebung des körperlichen und psychosozialen Gesundheitszustands darstellender Künstlerinnen und Künstler
Authors: Schemmann Heike , Zalpour Christoff , Ballenberger Nikolaus 
Published: June 2024

Abstract

Background
Health care providers like physiotherapists should address the needs of performing artists for a specific health care derived from physical and psychosocial (performance-related) complaints. The aims of this study were (1) to compose an algorithm including subjective outcome measures in order to suggest how to evaluate the physical and psychosocial health status of performing artists in its complexity in a manner as targeted and detailed as possible, and (2) to test the feasibility of applying this algorithm.

Methods
Questionnaires regarding different health dimensions were searched and assembled to an algorithm. The survey was applied to performing artists in order to test feasibility. The respective questionnaires were scored and interpreted in comparison to cut-off values.

Results
Performing-art-specific and body-region-specific standardized questionnaires in German with the highest possible psychometric quality were selected. The algorithm covers a series of questionnaires on health-related quality of life, complaints in physical matters—especially musculoskeletal and voice-specific—and in the psychosocial area. Based on specific predefined decision criteria the artist was guided individually through the survey. This was illustrated by the participants' flow through the survey. Profiles of physical and psychosocial complaints for subgroups of 103 participants were built based on multiple scores and showed problems in both dimensions.

Discussion
It is possible to illustrate the physical and psychosocial health status of performing artists in a multidimensional way using the novel algorithm. It could be used both for groups and individuals to build complaint profiles for research and clinical purposes.
The Institution of Prime Minister and Government in A Hybrid Regime in Ukraine (1996–2021)
Authors: Prokop Maryana 
Published: June 2024

Abstract
Hybrid regimes are characterised by a balancing act between democracy and authoritarianism, with neither political regime type being dominant. The balancing of the state between democratic and non-democratic modes of functioning can take the form of a state transforming from authoritarianism to democracy and a form of regression from democracy to authoritarianism, when the democratic system is upset by non-democratic mechanisms. The functioning of the political system in Ukraine during the years 1996–2004 was such that the authoritarian aspects of Ukraine’s hybrid regime overshadowed its democratic elements. Steven Levitsky and Lucan Way (2002; 2013) refer to this phenomenon as “competitive authoritarianism”. This term denotes regimes where authoritarian features are more prevalent than democratic ones, according to the concept. Since 2004, the Ukrainian political system has transitioned towards a hybrid regime that places more emphasis on democratic characteristics. In the following twenty years, the Ukrainian hybrid regime was transformed between democratic-authoritarian hybrid regime (as a result of the events of the “Orange Revolution”, and the “Revolution of Dignity”) and authoritarian-democratic hybrid regime (during presidency L. Kuchma and V. Yanukovych). The hybridity of the political regime also translated into the functioning of the chief state bodies. The aim of this study was to find an answer to the question whether and to what extent did the hybridity of Ukraine’s political regime imply on the specificity of the functioning of the institutions of the prime minister and government in the state. The research hypothesis is that the hybridity of the Ukrainian political regime, as a stage of transition from authoritarianism to democracy, partly contributed to changing the traditional order of functioning of the institutions of prime minister and government in the state just formally losing the head of state’s dominant role in the process of government functioning.
Polski Fundusz Rozwoju jako podmiot wspierający przedsiębiorców (ujęcie prawne)
Authors: Woroniecki Paweł Marek 
Published: June 2024

Przedmiotem artykułu jest prezentacja mechanizmu wsparcia udzielanego przedsiębiorcom przez Polski Fundusz Rozwoju. W ramach tak określonego problemu badawczego wyznaczono – w formie pytań – trzy cele szczegółowe opracowania. Po pierwsze, jakie są cele wsparcia i jakie podmioty mogą korzystać z pomocy Funduszu. Po drugie, jakie są formy prawne i zasady udzielania wsparcia przez Fundusz. Po trzecie, jakie są źródła finansowania Funduszu. W artykule przyjęto metodę badawczą polegającą na analizie przepisów prawnych zawartych przede wszystkim w ustawie z dnia 4 lipca 2019 r. o systemie instytucji rozwoju (tekst jednolity: Dz.U. z 2023 r. poz. 1103 z późn. zm.). Przeprowadzone rozważania potwierdziły trafność sformułowanej w artykule hipotezy, iż Polski ustawodawca wyposażył Fundusz w instrumenty prawne umożliwiające skuteczne wspieranie przedsiębiorców. Tym niemniej sformułowano pod adresem ustawodawcy pewne rekomendacje pozwalające na udoskonalenie mechanizmu wsparcia. Po pierwsze, należy postulować zmianę art. 13 ust. 1 ustawy o systemie instytucji rozwoju poprzez rozszerzenie katalogu papierów wartościowych, które mogą być nabywane przez Polski Fundusz Rozwoju celem wsparcia przedsiębiorców. Po drugie, rekomenduje się zmianę ustawy o systemie instytucji rozwoju w kierunku poszerzenia możliwości finansowania Polskiego Funduszu Rozwoju przez przekazywanie mu akcji spółek Skarbu Państwa. Po trzecie, należy jednoznacznie wprowadzić do ustawy o systemie instytucji rozwoju możliwość wystawiania przez Fundusz weksli celem finansowania realizacji rządowego programu udzielania wsparcia finansowego.
The problems of the theory of the reference of signs in modern linguistics
Authors: Chilingaryan Kamo Pavelovich 
Published: June 2024

The subject of the study is the history of the development and current state of the theory of reference, which reflects a variety of approaches and concepts. Some researchers believe that reference is a purely semantic phenomenon, while others emphasize the importance of context and pragmatics for understanding referentiality. The issue of the influence of cultural and social factors on reference in various languages is also being actively investigated. The history of the development of the theory of reference began with the works of Gottlob Frege and Bertrand Russell at the beginning of the 20th century. Frege introduced the concept of semantic reference, arguing that every word has its own referent in the world. Russell developed this idea by proposing a theory of descriptions, according to which words indicate objects by describing their characteristics. The works of Ludwig Wittgenstein and Donald Davidson played an important role in the further development of the theory of reference. Wittgenstein proposed the concept of language games, arguing that reference depends on the context and use of a word in a certain situation. Davidson developed the theory of truth, according to which reference is determined through the connection between language and the world. The pragmatic and cognitive aspects of research methodology are important for the successful conduct of scientific research. The referential nature of signs plays a key role in this process, ensuring effective presentation and communication of research results. The scientific novelty of the research lies in a comprehensive examination of the classical works of philosophers, semiotics and linguists, including Plato, Aristotle, Charles Pierce, Ferdinand de Saussure and Umberto Eco, on the theory of reference. One of the key concepts in the study of sign systems is referential. Referentiality allows to associate words with specific objects and understand their meaning. One of the most relevant areas of research in the field of reference is the study of ways in which linguistic units interact with the context and situation of communication. This allows for a deeper understanding of the processes of notation and interpretation in language, as well as the development of new theoretical models explaining these processes. Thus, scientific novelty in the study of the referentiality of signs continues to be relevant and important for the development of linguistics and related disciplines. The author's contribution in this area may lead to new discoveries and understanding of the mechanisms of linguistic communication.
New media as a subject of political communication
Authors: Arutiunian Elina  Gegamovna , Baichik Anna Vitalievna , Blochin Igor Nikolaevich , Petrosyan David Vladimirovich 
Published: June 2024

The media space is the most dynamic and rapidly developing not only technological, but also economic, cultural, social and political phenomenon of our time, and new communication channels are being formed in the global digital network. The purpose of the article is to analyze new media as a subject of the political process. The subject is new media, and the object is the cultural and political identification of an individual in new media. The novelty of the work lies in the fact that new media are an innovative and extremely important tool in determining cultural and political identity. Countries belong to the same civilization, which means that their culture is based on identical values – this is of fundamental importance, since the effectiveness of the imposed system of values and norms can be realized in a particular country only if the tasks being disseminated are consonant with the values of society. Conceptual, phenomenological and sociolinguistic analysis, the method of system analysis, and the historical and cultural method were used as methods and approaches. As a result of a comprehensive analysis, the following conclusions were drawn: the disseminated values can be effective only if they are in tune with the civilizational model of the region, and on the contrary, the imposed foundations will not effectively affect society if they contradict its civilizational identification and cultural and political affiliation. The actions of an individual and society as a whole are determined by his self-identification, therefore, a political course can be effective in a particular country if the tasks being implemented are consonant with the values of society. This study may be useful for researchers studying communication in the digital environment, the impact of new media on the agenda, the realization of political goals through online media, as well as for international journalists, diplomats, political scientists and media researchers when writing analytical materials on topics related to the working concepts of the current study.
Thermal and organic matter modeling in the fault bend fold and fault propagation fold structural models
Authors: Sarmiento R. L. F. , Piedrahita C. C. , Montaña R. C. A. 
Published: June 2024

In Colombia the areas of greatest petroleum exploration interest are characterized by complex structure with folds and thrust faults where it is important to estimate the thermal effects of faults to evaluate organic matter maturity and hydrocarbon generation processes. Except for a software model recently developed by the French Petroleum Institute (Francois Roure personal communication), current and public domain one dimension models do not consider lateral or downward heat flow, which are of normal occurrence in these areas, in addition such models assume instantaneous fault movement contrary to geologic observations. For balanced cross sections with (1) fault bend folds and (2) fault propagation folds we model heat conduction from the basement and organic matter maturity; outputs of the model are temperature and organic matter maturity at each point of the sections at different times while deformation is occurring. Boundary conditions are: absence of lateral heat flow on the lateral border of the sections, constant heat flow at the bottom of the sections, and constant temperature at the surface of the earth. The heat conduction equation applied to the sections was solved by the finite element numerical method with the ANSYS software. The obtained results for different deformation rates are shown and analyzed. Results show lateral variations of temperature and organic matter maturity. Contrary to one dimensional models, the steady state in two dimensions is reached faster, it is cooler and the temperature inversion is shorter. The less deformation rate the less thermal anomaly. At the topographic peaks temperature and maturity are lower than in the valleys. The fault propagation section presents a depth maturity inversion more pronounced than in the fault bend fold model. Depth maturity inversion intensity depends on the ratio between the deformation time Td and the time passed just after deformation ceased Tp: Td /Tp. If this ratio is greater the depth maturity inversion will be greater. This paper shows the possibility to determine the organic matter distribution in a structural section with a known thermal and deformation history.
Allelopathic impact of Chromolaena odorata on the local crops in Mizoram, India
Authors: Sengupta Rabishankar , Dash Sudhansu Sekhar 
Published: June 2024

Allelopathy is the major biological advantage of an invasive alien plant, often inhibitory to the germination and growth of other plants within their space. This study aimed to demonstrate the allelopathic effect of Chromolaena odorata extracts on seed germination and seedling growth of four commonly grown crops as test plants in Mizoram. Chromolaena odorata was observed as one of the dominant invasive alien plants in the natural forests of Mizoram with increased abundance and lower diversity in the invaded areas during frequent field visits. Petri plate and pot bioassay study revealed that the increasing concentrations (control, 2.5, 5, 7.5, 10 and 15%) of aqueous extracts or leachates inhibited seed germination, root and shoot length, vigour index. Bioassay treatment of the test plants with a higher concentration of C. odorata extract exhibited a significant inhibition of germination and test plant growth. Preliminary phytochemical analysis exhibited the presence of Alkaloids, Tannins, Saponins, Terpenoids and Flavonoids. The inhibitory effects on seed germination confirmed the inhibitory allelopathic potential of Chromolaena odorata in cultivated lands of Mizoram which may be attributed to presence of the allelochemicals in the leaf and stem extracts of the IAPs.
EFEKTIVITAS PECS (PICTURE EXCHANGE COMMUNICATION SYSTEM) DALAM MENINGKATKAN KEMAMPUAN KOMUNIKASI ANAK AUTIS
Authors: Tiara Pabela  , Indria Musalmah  , Nurhayani Lubis  , M. Fahri Nasution  , Aldo Kurniawan  
Published: June 2024

Penelitian ini bertujuan untuk mengetahui seberapa efektif sistem komunikasi dengan PECS dapat meningkatkan kemampuan komunikasi anak autis. Subjek penelitian merupakan kelompok eksperimen anak autis berusia 8 tahun yang bersekolah di SLB Permata Bunda.Tujuan dari penelitian ini untuk menguji hipotesis metode gambar melalui PECS (Picture Exchange Communication System) terhadap kemampuan komunikasi anak autis dalam rentang waktu 4 sesi pertemuan intervensi. Masing-masing sesi dilakukan dengan durasi 40-60 menit menggunakan 5 tahapan pada perlakuan menggunakan metode PECS. Penelitian ini adalah kuasi eksperimen dengan jenis One-Group Pretest Posttest Design. Data diambil melalui observasi dan instrumen kemampuan berbahasa reseptif, ekspresif dan kognisi sosial anak autis. Teknik analisis data berupa statistik menggunakan uji Wilcoxon Signed Test, dengan nilai signifikansi 0,180 > 0,05. Hal ini menunjukkan metode gambar yang digunakan melalui PECS tidak memiliki dampak yang signifikan pada peningkatan komunikasi anak autis.
МОЖЛИВОСТІ ВИКОРИСТАННЯ ТЕХНОЛОГІЇ «ШЕСТИ КАПЕЛЮХІВ» У РОЗВИТКУ МИСЛЕННЯ ШКОЛЯРІВ З ДИСЛЕКСІЄЮ (НА ПРИКЛАДІ ВИВЧЕННЯ ДИТЯЧИХ ТВОРІВ К. ЄГОРУШКІНОЇ)
Authors: Поліщук Віра , Цегельник Тетяна , Харчук Яна 
Published: June 2024

Освіто-виховний процес за своїм змістом і технологією здійснення потребує постійного оновлення відповідно до нових змін, завдань і викликів, які ставить життя перед оновленою українською школою. Вдосконалення навчально-виховного потенціалу сучасного уроку – це далеко не тільки внесення змін в традиційну його структуру, але й нові підходи до формування уявлень про світ, життя, його цінності, майбутнє цивілізації. Вирішенню цих завдань у значній мірі сприяють інноваційні технології. Мета статті полягає в аналізі потенційних можливостей використання технології «шести капелюхів» у розвитку творчого мислення і мовленнєвих здібностей дітей з особливими освітніми потребами. Для забезпечення достовірності положень та висновків, досягнення мети використано комплекс методів дослідження: теоретичних – аналіз, синтез, порівняння та узагальнення інформації на українських і зарубіжних веб-сайтах, а також вивчення публікацій в електронній базі даних Google Scholar. Здійснено аналіз змісту наукових дефініцій: інноваційні технології, дислексія та чинники її виникнення, системний аналіз можливостей технології «шести капелюхів» у формуванні мислення і мовлення дітей з особливими освітніми потребами. Аналіз технології розглядається на прикладі роботи з дітьми з дислексією у процесі вивчення дитячих творів К. Єгорушкіної. У дослідженні виокремлено векторність потенціалу досліджуваної методики, обґрунтовано необхідність її застосування у процесі мисленнєвого розвитку дітей окресленої категорії. У процесі дослідження доведено, що, маючи на меті успішну інтеграцію дитини з дислексією у суспільне середовище, необхідною є рання діагностика специфічних аспектів її психічного розвитку, котрі суттєво ускладнюють проблематику в мисленнєвій сфері, з метою реалізації ефективної спеціалізованої корекційної допомоги.
Bridging the genetic gulf: a deep dive into neurotransmission, pharmacogenomics, and genetic variations for optimal pain management
Authors: Jani Jaeyres , Liew Sat Lin Constance , D. Mudin D. Kamarudin , Muniandy Rajesh Kumar 
Published: June 2024

Pain embodies a complex sensory experience influenced by a medley of biological, psychological, and genetic. Pain perception can be classed into four main categories: nociceptive pain, neuropathic pain, acute pain, and chronic pain. Genetic polymorphisms, which are basically genetic variations in DNA sequences, have a part to play in the neurotransmission pathways associated with pain perception and the ultimate effectiveness of pain management interventions. Learning about the effects of genetics on neurotransmission in pain management offers a fresh viewpoint on individual variations in pain sensitivity, response to treatment, and the development of personalised approaches to pain management. A closer look at the relationship between genetic polymorphisms and neurotransmission provides a better understanding deep down at the genetic level. These chemical messengers, neurotransmitters, help pass signals between nerve cells; they are essential for pain processing and modulation. Differences in genetic makeup in neurotransmitter-related genes could change how these genes express, function, and regulate, thus changing how humans perceive pain and respond to pain management interventions. The conjunction of neurotransmission and pharmacogenomics forms a unique convergence, composing a narrative that discloses the percipient influence of individual genetic differences on neural communication and responses to pharmaceuticals. These genetic variations elaborately construct the molecular architecture supervising neurotransmitter release, receptor interactions, and enzymatic processes within the nervous system. In this review, the convergence of neurotransmission, pharmacogenomics, and genetic variations illuminates a pivotal realm in healthcare. Genetic variations intricately influence neurotransmission pathways, moulding individual responses to pharmacological interventions. This intersection not only underscores the complexity of human biology but also holds the promise of personalised healthcare solutions. Recognising subtle genetic variations in neurotransmission and pharmacogenomics opens the door to precision medicine, tailoring treatments to individual genetic codes and revolutionising our approach to medical care.