bluuebunny/crossref_metadata_2025_split huggingface dataset:
Anchoring Tri(8-Quinolinolato)Iron Onto Sba-15 for Partial Oxidation of Benzyl Alcohol Using Water as the Solvent
Authors: Yang Xiaoyuan , Liu Jing , Kan Qiubin , Guan Jingqi 
Published: July 2014

Abstract
Tri(8-quinolinolato)iron complex immobilized onto SBA-15 catalyst has been synthesized through a stepwise procedure. The characterization results indicated that the BET surface area, total pore volume and average pore width decrease after stepwise modification of SBA-15, while the structure keeps intact. Catalytic tests showed that FeQ3-SBA-15 catalyzes the oxidation reaction well with 34.8% conversion of benzyl alcohol and 74.7% selectivity to benzaldehyde when water is used as the solvent after 1 h reaction. In addition, homogeneous catalyst tri(8-quinolinolato)iron exhibits very bad catalytic behavior using water as the solvent.
Groundwater Quality in the Shallow Aquifers of the Hadauti Plateau of the District of Baran, Rajasthan, India
Authors: Kumar Lokesh , Rakshit Amitava 
Published: July 2014

Abstract
With the rapid pace of agricultural development, industrialization and urbanization, the commonly observed geogenic contaminants in groundwater are fluoride and nitrate, whereas nitrate is the dominant anthropogenic contaminant in the south-eastern plains of Rajasthan, India. Samples obtained using a tube well and hand pump in November, 2012, demonstrate that Na-Cl is the dominant salt in the groundwater, and the total salinity of the water is between 211-1056 mg L-1. Moreover, the observed sodium adsorption ratio (SAR) and residual sodium carbonate (RSC) values ranged between 0.87 to 26.22 meq L-1 and -12.5 to 30.5 meq L-1 respectively. The study further shows that 6% of the total samples contain high amounts of nitrate, and 49% contain fluoride. A water quality index (WQI) rating was carried out using nine parameters to quantify the overall groundwater quality status of the area.
Evaluation of the Aggressiveness of Slovak Mineral Water Sources
Authors: Vrablíková Dana , Porubská Diana , Fendeková Miriam , Božíková Jarmila , Kókaiová Denisa 
Published: July 2014

Abstract
The aggressive properties of natural waters arise due to their specific physical properties and chemical composition. The latest analyses of certified natural and healing mineral water sources according to Act No. 538/2005 were used for the evaluation. A total of 53 sources in 26 localities were evaluated; they comprised 25 sources of bottled natural mineral and healing waters and 28 sources of natural healing waters in 9 spas. The aggressiveness of the water against concrete was weak (17 sources), medium (17 sources), or none (19 sources). The aggressiveness was mostly caused by low pH values and/or increased SO4
2− content. Their corrosiveness to metal was mostly very high. The results showed that the disintegration of concrete building constructions, well casings and pipelines could occur in most of the evaluated localities in the case of mineral water contacting them. Therefore, preventive measures are necessary.
Grain Size Measurement in Experimental Co-Re-based Alloys to Study Grain Coarsening, Part I
Authors: Czerny Andreas Klaus , Mukherji Debashis , Rösler Joachim 
Published: July 2014

Abstract
Co-Re-based alloys being developed for high temperature applications and produced by vacuum arc melting have rather small grain size. Large grain sizes are desirable in such alloys for better resistance to high temperature creep. However, no systematic studies on grain coarsening in Co-Re alloys were conducted so far. In this paper grain coarsening at 1000°C and 1200°C were investigated by using three different Co-Re alloys with and without second phase precipitates. Different methods for grain size measurement including EBSD were employed in this study. Co-Re alloys showed inhibition to grain growth, but microstructural features like precipitates or twins are not responsible for this behaviour. Further investigations are needed to find the real cause but slow diffusion of the heavy rhenium atom in Co-matrix may be responsible.
Sustainable Agricultural Development under Climate Change in Bangladesh
Authors: Faroque MAA , Asaduzamman M , Hossain M 
Published: July 2014

Climate change is no more an environmental concern it has emerged as biggest developmental challenge for the most vulnerable Bangladesh. The whole international community is also scared of catastrophic adverse effects of future climatic changes on different spheres of man and nature, e.g. deglaciation and sea level changes, submergence of lands, nations and major coastal lowlands, atmospheric dynamics including evaporation and precipitation, global radiation balance, photosynthesis and ecological productivity, plant and animal community and many more. This paper tries to focus the adverse impacts of climatic changes on the crop production, food security, yield gap and sustainable agriculture by crop intensification and diversification. The impact of climate on agriculture could result in problems with food security and may threaten the livelihood activities upon which much of the population depends and thrives. Hilly committed research efforts showed technological progress as evidenced by release of 684 high yielding varieties of various crops and about 769 management technologies by NARS institutes, and universities. The greatest challenge for the future agriculture under climate change, we need improved and modified warning system, developed climate impact modules, build sufficient resilience of food system, comprehensive climate resilience strategies, develop database on climate. Also need top priority to mitigate the impact of climate change on agriculture through weather services, more research and extension service, agro advisories, insurance, community bank, intensify and diversify crop production system, modern high yielding varieties and management technologies for future sustainable agriculture.DOI: http://dx.doi.org/10.3329/jsf.v11i1.19396
Dosimetric measurements of 68Ga-High Affinity DOTATATE
Authors: Freudenberg R , Oehme L. , Zöphel K. , Schottelius M. , Wester H.-J. , Wunderlich G. , Kotzerke J. , Brogsitter C. , Hartmann H. 
Published: July 2014

SummaryPurpose: 68Ga-labelled compounds are increasingly used for somatostatin-receptor scintigraphy because of their favourable biokinetic properties, a higher tumour-to- background contrast and higher diagnostic accuracy compared to the gamma-emitting tracer 111In-DTPA-octreotide. Recently, we have introduced the new tracer 68Ga-DOTA- 3-iodo-Tyr3-Thr8-octreotide (68Ga-HA-DOTA- TATE). The present study demonstrates the biodistribution and radiation dosimetry of this tracer in humans. Patients, methods: Seven men were enrolled in this analysis. Every patient underwent a 20 min dynamic PET scan after intravenous injection of about 114 ± 9 MBq of 68Ga-HA-DOTATATE. This was followed by two whole-body scans at 30 min p. i. and 120 min p. i. Blood radioactivity concentration was determined non-invasively from a ROI drawn over the aorta. Urine was collected until the time of the last scan. Liver, spleen, kidneys and urinary bladder wall were included in the dosimetric estimation that was carried out with the software package OLINDA 1.0. Results: Physiological 68Ga- HA-DOTATATE uptake was observed in the pituitary gland, thyroid, salivary glands, liver, spleen, kidneys, urinary bladder, adrenals and intestine. Organs with the highest absorbed dose were spleen (0.26 ± 0.11 mSv/MBq), kidneys (0.14 ± 0.03 mSv/MBq) and liver (0.12 ± 0.02 mSv/MBq).The estimated effective dose was 0.024 ± 0.001 mSv/MBq. Conclusion: Our study demonstrates biokinetics and radiation exposure of the 68Ga-labelled tracer HA-DOTATATE to be comparable to other 68Ga-labelled SSR analogues in clinical use.
Nanoforging – Innovation in three-dimensional processing and shaping of nanoscaled structures
Authors: Landefeld Andreas , Rösler Joachim 
Published: July 2014

Background: This paper describes the shaping of freestanding objects out of metallic structures in the nano- and submicron size. The technique used, called nanoforging, is very similar to the macroscopic forging process.Results: With spring actuated tools produced by focused ion beam milling, controlled forging is demonstrated. With only three steps, a conical bar stock is transformed to a flat- and semicircular bent bar stock.Conclusion: Compared with other forming techniques in the reduced scale, nanoforging represents a beneficial approach in forming freestanding metallic structures, due to its simplicity, and supplements other forming techniques.
Association of Anticyclic Citrullinated Peptide Antibodies and/or Rheumatoid Factor Status and Clinical Presentation in Early Arthritis: Results from the ESPOIR Cohort
Authors: Mouterde Gaël , Lukas Cédric , Goupille Philippe , Flipo René-Marc , Rincheval Nathalie , Daurès Jean-Pierre , Combe Bernard 
Published: July 2014

Objective.To compare the initial clinical, biological, and radiographic findings of early arthritis by positivity for rheumatoid factor (RF) and/or anticyclic citrullinated peptide antibodies (anti-CCP), and to validate a patient profile based on this serologic information.Methods.The ESPOIR cohort comprises patients presenting synovitis of at least 2 joints for 6 weeks to 6 months. Patients underwent testing for IgM rheumatoid factor (IgM-RF) and anti-CCP2 antibodies and were divided into 4 groups: RF– and anti-CCP– (group 1), RF+ and anti-CCP– (group 2), RF– and anti-CCP+ (group 3), RF+ and anti-CCP+ (group 4). We compared the groups in terms of clinical, biological, and radiographic features (baseline scores and 6-month and 12-month progression).Results.Of the 813 recruited patients, 406 (50%) were in group 1, 91 (11.2%) in group 2, 34 (4.1%) in group 3, and 281 (34.6%) in group 4. Mean baseline erythrocyte sedimentation rate and C-reactive protein were higher for anti-CCP+ groups (groups 3 and 4) than for other groups (p < 0.001), and van der Heijde-modified Sharp score for radiographs was higher for group 4 than for other groups (p < 0.001). Clinical presentation was not consistently associated with serologic profile. Radiographic progression at 1 year was higher for anti-CCP+ groups than other groups (p < 0.001).Conclusion.The phenotype of patients with early arthritis with or without anti-CCP and/or RF positivity did not correspond to a particular clinical presentation. However, baseline acute-phase reactants and short-term radiographic progression were high in patients with anti-CCP positivity, which may be associated with the inflammatory process and progressive disease in patients with early arthritis.
Circulating Concentrations of the Novel Adipokine Chemerin Are Associated with Cardiovascular Disease Risk in Rheumatoid Arthritis
Authors: Dessein Patrick H. , Tsang Linda , Woodiwiss Angela J. , Norton Gavin R. , Solomon Ahmed 
Published: July 2014

Objective.Depending on physiological context, the adipokine chemerin can reduce or enhance cardiovascular risk. We investigated whether chemerin concentrations represent cardiovascular disease risk in rheumatoid arthritis (RA).Methods.We assessed ELISA-determined chemerin concentrations and those of 4 early endothelial activation molecules as well as angiopoietin 2, which mediates angiogenesis and thereby contributes to advanced atherosclerosis, the common carotid artery intima-media thickness (cIMT), and carotid artery plaque by ultrasound in 236 patients (114 black and 122 white) with RA. Relationships were identified in potential confounder and mediator-adjusted mixed regression models.Results.Mean (SD) chemerin and median (interquartile range) angiopoietin 2 concentrations were 114 (35) ng/ml and 2560 (2044–3341) pg/ml, respectively; the mean (SD) cIMT was 0.708 (0.110) mm, and 40.3% of patients had plaque. Chemerin concentrations were not related to those of early endothelial activation molecules, but associated with those of angiopoietin 2 [β SE = 0.002 (0.0004), p < 0.0001] and plaque [OR 1.006 (95% CI 1.00–1.013), p = 0.05] in all patients. The presence of major conventional cardiovascular risk factors, generalized and abdominal obesity, and RA severity markers modified the independent chemerin-cardiovascular risk relations (interaction p < 0.05). Consequently, chemerin concentrations were associated with cIMT in those with but not without overweight or generalized obesity and abdominal obesity [β SE = 0.001 (0.0003), p = 0.005 and 0.001 (0.0001), p = 0.001 vs −0.001 (0.0004), p = 0.2 and −0.0002 (0.0004), p = 0.6, respectively], and with plaque in those without but not with generalized obesity [OR 1.008 (95% CI) 1.000–1.016, p = 0.03 vs 1.003 (0.990–1.017), p = 0.6, respectively]. The β (SE) for the chemerin-intima-media thickness relations in patients with overweight or generalized obesity and abdominal obesity were larger than in those without these characteristics (p < 0.0001 and = 0.04, respectively).Conclusion.Chemerin is associated with endothelial activation and atherosclerosis in RA. Adiposity influences the chemerin-atherosclerotic phenotype relations in RA.
Vous avez dit « puissance civile » ?
Authors: Bersick Sebastian , Gottwald Jörn-Carsten 
Published: July 2014

En 2003, la République populaire de Chine et l’Union européenne ont décidé d’intensifier leurs relations bilatérales sous la forme d’un Partenariat stratégique. Dix ans plus tard, les trois piliers du « Dialogue politique », du « Dialogue économique et sectoriel » et du « Dialogue de peuple à peuple » symbolisent l’ambition d’un partenariat global. En dépit d’une augmentation rapide non seulement des échanges commerciaux bilatéraux, mais aussi des forums et des commissions de coopération bilatérale, la majorité du monde universitaire est toujours sceptique : où la dimension stratégique de la relation apparaît-elle donc ? Qu’est-ce que cela signifie pour le partenariat ? Et existe-t-il même vraiment une politique européenne unifiée et cohérente vis-à-vis la Chine ? Au-delà du débat sur la politique chinoise de l’Europe, sa substance et sa cohérence stratégiques, la perte insidieuse de puissance normative européenne, qui va en s’accélérant depuis lors et au travers des turbulences dans le sillage de la crise financière mondiale, est beaucoup plus fondamentale. Initialement, les relations bilatérales visaient explicitement à amener la Chine plus près des normes et standards économiques, juridiques et politiques acceptés dans le monde entier et appliqués en Europe. Entre-temps, et justement en ce qui a trait aux relations économiques et financières des deux parties, l’UE compte sur le soutien de la Chine comme nouveau chef de file mondial, alors qu’elle-même a cessé d’espérer une contribution européenne à son processus de changement et de réforme intérieur. La perception chinoise changeante du Partenariat stratégique ne révèle pas seulement un déclin de l’importance de l’UE pour les questions d’actualité, mais également un positionnement fondamentalement nouveau de la République populaire de Chine en tant que puissance normative. L’UE, d’un autre côté, semble avoir abandonné toute ambition de façonner le rôle de la Chine dans les relations internationales. La relation spéciale qui prend de l’importance entre l’Allemagne et la Chine a renforcé cette tendance. Le Partenariat stratégique apparaît de plus en plus comme le portail de l’ascension de la Chine et de la perte de puissance auto-infligée de l’Europe. Il n’y a que peu d’indicateurs permettant d’espérer un renouveau de la puissance normative de l’Europe, en dépit de l’enthousiasme originel avec lequel l’Europe planifiait d’assumer son rôle et de le façonner activement dans le monde, et en particulier avec la Chine en tant que nouvelle grande puissance.
Economic relations between the European Union and China
Authors: Inotai András 
Published: July 2014

Plusieurs facteurs ont contribué au commerce, qui se développe rapidement, et aux relations économiques entre l’Union européenne et la Chine dans les quinze dernières années : l’adhésion de la Chine à l’OMC, le changement dans les rapports de force (économiques) mondiaux, la délocalisation des entreprises européennes en Chine avec réexportations de marchandises produites en Europe, ainsi que la crise mondiale et ses conséquences. À partir de statistiques de base, cet article traite des questions institutionnelles, commerciales et des questions liées à la politique commerciale. Un chapitre est consacré à l’analyse d’un domaine encore ‘sous-développé’, celui de la coopération bilatérale, par l’évolution des flux bilatéraux d’investissements directs, avec un accent particulier sur les motivations des entreprises chinoises à entrer sur le marché de l’Union européenne. La coopération financière a connu une amélioration qualitative, à la fois comme résultat de la crise de l’euro et du niveau croissant sans précédent des réserves chinoises de change. Malgré une interdépendance croissante, les stéréotypes anciens et de plus en plus obsolètes sont encore vivants et doivent être surmontés afin d’ouvrir la voie à une coopération à part entière. Cette dernière ne peut se limiter à des questions bilatérales, car l’UE et la Chine assument ensemble une responsabilité globale pour un large éventail de défis auxquels elles doivent faire face au xxi e siècle. Une intégration plus poussée de l’UE serait utile non seulement pour favoriser l’ancrage autour de l’UE d’un modèle international de croissance et développement plus équilibré et durable, mais aussi pour une meilleure intégration de la Chine dans un ordre mondial multipolaire (et multilatéral).
1994-2014 : quelle organisation de l'intelligence économique d'entreprise en France ?
Authors: Lucas Didier , Moinet Nicolas 
Published: July 2014

L’intelligence économique française fête cette année son vingtième anniversaire officiel. Depuis 1994 et la sortie du rapport Martre, les pratiques se sont diffusées et ont évoluées. Après avoir donné un panorama historique de l’ organisation de l’intelligence économique dans les entreprises française, il apparaît intéressant de les caractériser selon trois types : « dynamique intégrée », « pratiques isolées » et « fonctions disséminées ». Cette typologie permet de mieux appréhender cette dynamique au sein des organisations et d’insister sur les deux maillons faibles généralement rencontrés : l’analyse et le management des connaissances.
Le Plan cancer 2014-2019 : un plan de lutte contre les inégalités et les pertes de chance face à la maladie
Authors: Buzyn Agnès 
Published: July 2014

C’est dans le champ du cancer que les inégalités de santé sont parmi les plus importantes en France. Face à ce constat, le nouveau Plan cancer a été conçu comme un véritable « plan de lutte contre les inégalités », avec pour objectif d’accroître les connaissances sur cette problématique et de les opérationnaliser au travers d’interventions. L’impact de ces efforts sera mesuré grâce au développement de nouveaux indicateurs sociosanitaires, favorisé par l’appariement de bases de données administratives et de santé. L’inscription, en majeure, de la lutte contre les inégalités dans ce Plan doit également amener l’ensemble des acteurs intervenant dans le domaine du cancer à développer une position réflexive, à titre individuel ou collectif, quant aux pertes de chance à l’œuvre face à la maladie, et aux moyens de les réduire.
Once-weekly liposomal amphotericin B for prophylaxis of invasive fungal infection after graft-versus-host disease in allogeneic hematopoietic stem cell transplantation
Authors: Cheikh Jean El , Castagna Luca , Wang Ling , Esterni Benjamin , Faucher Catherine , Furst Sabine , Duran Segolene , Berger Pierre , Ranque Stephane , Mohty Mohamad , Blaise Didier 
Published: July 2014

BACKGROUND AND OBJECTIVES:
The liposomal formulation of amphotericin B (LA mB) has been shown to cause few and mild infusion-related reactions, while achieving high plasma and tissue concentrations compared with conventional amphotericin B. We investigated the efficacy and safety of high-dose LA mB (7.5 mg/kg once weekly) prophylaxis of fungal infections in allogeneic stem-cell transplanted (allo-SCT) patients with graft-verssus-host disease (GvHD).

DESIGN AND SETTING:
Retrospective, comparative, single-center.

METHODS:
Forty-two patients receiving high-dose prednisone for GvHD after allo-SCT had LA mB prophylaxis; 83 patients in the control group received other antifungal prophylaxis.

RESULTS:
In the LA mB prophylaxis group, the median duration of treatment was 7 weeks. The cumulative inciddence of invasive fungal infection was 8% at 1 year after transplantation, 8% at 2 years and 16% at 3 years in the LA mB group vs. 36% at 1 year, 44% at 2 years and 49% at 3 years in the other prophylaxis group (P=.008). Fungal infection-related mortality after transplantation was observed in none of the patients in the LA mB prophyllaxis group vs. 12 patients (14%) at 1 year, 14 patients (17%) at 2 years and 16 patients (19%) at 3 years in the control group (P=.005). The tolerance of the treatment was good with only 5 patients (12%) having a reversible nephrotoxicity leading to temporary treatment discontinuation.

CONCLUSIONS:
High-dose LA mB prophylaxis seems effective and well tolerated in this short series of allo-SCT patients with GvHD . Prospective clinical studies are required to confirm these results.
Cardiac events and cardiac T2* in Egyptian children and young adults with β-thalassemia major taking deferoxamine
Authors: Elalfy Mohsen S. , Abdin Iman A. , El Safy Usama R. , Ibrahim Ahmed S. , Ebeid Fatma S. , Salem Doria S. 
Published: July 2014

BACKGROUND AND OBJECTIVES:
Cardiac events and death are not uncommon in adults with β-thalassemia (β-TM) taking deferoxamine (DFO) monotherapy because of poor compliance and possibly the less effectiveness of DFO in controlling cardiac iron overload. We sought to assess compliance with DFO, the percentage of shift to other iron chelators, and the occurrence of cardiac siderosis, and cardiac events and death in β-TM patients on DFO monotherapy.

DESIGN AND SETTING:
Prospective, observational, 10-year follow-up of patients attending Ain Shams Thalassemia Unit, Cairo, Egypt.

METHODS:
For all β-TM patients aged 2-18 years attending the unit during January 1998 and taking DFO, we recorded all cardiac events (whether fatal or not) during January 2008. All patients still on DFO monotherapy and with a normal EKG and not showing symptoms or signs suggestive of heart failure (HF) were evaluated for cardiac siderosis by T2*.

RESULTS:
Of 412 patients, only 126 (31%) were still taking DFO monotherapy (only 43% of those were compliaant), 136 were taking combined DFO and deferiprone (DFP), 72 were taking DFP and 32 were taking deferasirox (DFX). Twenty-one were lost follow-up and 25 died (10 cardiac). Eight of ten cardiac deaths and 12 of 15 non-carddiac deaths were in the DFO monotherapy group. Those taking DFO monotherapy with no HF and left ventricular ejection fraction (LVEF) by T2* >56% had a median age of 19 years and 56% were males; cardiac T2* was <20 ms in 30 (22%); 10-20 ms in 20 (14.7%) and <10 ms in 10 (7.3%). LVEF ranged from 58%-76 % (median 64%). Forty percent of T2* patients <10 ms were compliant with DFO.

CONCLUSION:
Fifty-eight percent of patients on DFO monotherapy were noncompliant, but even compliance did not prevent severe cardiac siderosis and most cardiac events (whether fatal or not) that occurred in the DFO monotherapy group.