bluuebunny/crossref_metadata_2025_split huggingface dataset:
CD36, but not GPR120, is required for efficient fatty acid utilization during endurance exercise
Authors: Fujitani Mina , Matsumura Shigenobu , Masuda Daisaku , Yamashita Shizuya , Fushiki Tohru , Inoue Kazuo 
Published: July 2014

Abstract
Fatty acids (FA) are an important energy source during exercise. In addition to its role as an energy supply for skeletal muscle, FA may activate signaling pathways that regulate gene expression. FA translocase/cluster of differentiation 36 (CD36) and G protein-coupled receptor GPR120 are long-chain FA receptors. In this study, we investigated the impact of CD36 or GPR120 deletion on energy metabolism during exercise. CD36 has been reported to facilitate cellular transport and oxidation of FA during endurance exercise. We show that CD36 deletion decreased exogenous FA oxidation during exercise, using a combination of 13C-labeled FA oxidation measurement and indirect calorimetry. In contrast, GPR120 deletion had no observable effect on energy metabolism during exercise. Our results further substantiate that CD36-mediated FA transport plays an essential role in efficient FA oxidation during exercise.
Preparation and immunogenicity of conjugate based on hydrazine-treated lipopolysaccharide antigen of Vibrio cholerae O139
Authors: Fleischhackerová Anna , Farkaš Pavol , Čížová Alžbeta , Bystrický Slavomír 
Published: July 2014

Abstract
A glycoconjugate construct was based on attachment of V. cholerae O139 hydrazine-treated lipopolysaccharide (LPS) to carboxylated bovine serum albumin (CBSA) via its amino group. The immunological properties of the glycoconjugate were tested using BALB/c mice, injected subcutaneously without any adjuvant three times at 2 weeks interval. The immunogenicity of the conjugate was estimated by enzyme-linked immunosorbent assay, testing of anti-LPS IgG, IgM, and IgA antibodies. The conjugate elicited a statistically significant increase of LPS-specific IgG levels in mice (p &lt; 0.001). The specific anti-LPS IgG and IgA response after the second booster dose was significantly higher compared with reference and unconjugated detoxified LPS response. Antibodies elicited by the dLPS–CBSA conjugate were vibriocidal.
Honeycomb: a spatio-temporal simulation model to evaluate management strategies and assessment methods
Authors: Needle Coby L. 
Published: July 2014

Abstract
In recent years, scientists providing advice to fisheries managers have been granted access to an increasing range of spatio-temporal data from fishing vessels, using tools such as vessel monitoring systems and electronic observation platforms. This information should allow for the provision of more germane advice on the activity of vessels, and hence the likely impact of management measures which are becoming increasingly spatial in nature. However, the development of appropriate management simulation and assessment models has lagged behind the availability of these new data. This paper presents an accessible spatio-temporal simulation framework (Honeycomb) which features a weekly time-step, multiple stocks and vessels, and economic decision rules and applies this to a case study of a spatial evaluation of a simple closed-area fishery policy. We conclude that the development and utilization of such spatio-temporal simulation models is a key research task for fisheries in which both spatial fisheries data and spatial fisheries management are becoming paramount.
Commissioning for nearly zero-energy building projects
Authors: Kantola Mikko , Saari Arto 
Published: July 2014

Purpose
– This article aims to reveal the benefits and opportunities that commissioning procedure has to offer for nearly zero-energy building (nZEB) projects. Another goal is to sculpture the commissioning process and, especially, commissioning consultant’s tasks to fit nZEB projects.

Design/methodology/approach
– The idea was to incorporate the literature from two fields: commissioning and nZEB, and find out if commissioning would fit nZEB projects. Challenges offered by nZEB technology were pointed out and the solutions offered to these problems by commissioning were established. Expert interviews were used to test the findings.

Findings
– Commissioning was found valuable for complex nZEB projects and even worthwhile investing to in simple nZEB projects. Quality assurance is a huge task when the change to nZEB construction happens in 2020 and commissioning can be a valuable tool to prevent large-scale quality problems. A number of additions were made to the example commissioning process used in Finland today.

Originality/value
– This article gives evidence for economical usability of commissioning procedure in nZEB projects and reason to start investigating the possibility to attach commissioning as a mandatory procedure to all nZEB projects.
You can't always get what you want: change management in higher education
Authors: Brown Stephen 
Published: July 2014

Purpose– The purpose of this paper is to qualitatively describe an attempt to enhance curriculum design and delivery processes in universities through the development and introduction of new information systems and procedures.Design/methodology/approach– The author examines the experiences of five out of the total 27 institutions involved in the UK JISC Curriculum Design and Delivery programme as they attempted to implement campus-wide changes.Findings– Common themes that emerged across all five projects were the interconnectedness of university systems, proliferation of alternative “feral” systems, a tendency for project remits to drift, resistance from other parts of the institution, planning imperatives, staff turnover and dependency failures. Conclusions are that cultural change underpins effective innovation and that cultural change is harder than technical innovation.Practical implications– Change is best achieved through participatory, campus-wide approaches, although a “submarine” strategy may be necessary to deflect opposition. Stakeholders should be kept informed about benefits to them and it is important for projects to be responsive and adaptive and to recognize that participatory approaches may be institutionally risky. The paper concludes with practical recommendations for achieving lasting large-scale change in the higher education environment.Originality/value– The JISC Curriculum Design and Delivery programme was arguably the largest single co-ordinated Information and Communication Technology-based change management programme yet seen in the UK and the findings of this study provide insights into common barriers to effective change in universities and how to overcome them.
Wadawurrung Dya Baap Ngobeeyt: teaching spatial mapping technologies
Authors: J. Woodley Carolyn , Fagan Sean , Marshall Sue 
Published: July 2014

Purpose
– Aboriginal communities in Australia must have mapping information and technology to effectively and independently administer their land holdings and to define, evidence and thus protect their community and cultural identity. The purpose of this paper is to report on a pilot project that developed a customisable education programme to support Indigenous communities in the uptake of spatial mapping technologies to protect and manage cultural heritage in Victoria, Australia.

Design/methodology/approach
– A training programme to support Wadawurrung capabilities in spatial mapping technologies was developed, delivered and evaluated. Concurrently, the system's database was indigenised by Wadawurrung cultural heritage workers. Types and numbers of culturally significant sites mapped using the technologies were collated. The impact of the training and technologies for students and the Wadawurrung community was gauged through participation levels and evaluations. The approach to indigenous spatial mapping projects is informed by postcolonial theories interrogating neo-colonialist cartographic practices.

Findings
– Indigenous communities need to be resourced in the uptake of spatial mapping technologies and if universities are going to be involved in co-developing positive learning experiences that encourage the uptake of the technologies, they must have appropriate and respectful relationships with Aboriginal communities. Training programmes need to accommodate learners with diverse educational experiences and technological wherewithal.

Research limitations/implications
– Findings from the training evaluations are based on a small number of participants; however, they seem to be supported by literature.

Practical implications
– The education model developed is customisable for any Indigenous community in Australia.

Social implications
– The social and political importance of spatial mapping technologies for Indigenous Australians is evident as is the need for educational providers to have appropriate and respectful relationships with Aboriginal communities to co-develop positive learning experiences that encourage the uptake of the technologies.

Originality/value
– The Wadawurrung Dya Baap Ngobeeyt Cultural Heritage Mapping and Management Project developed practical strategies to build community capacity in Aboriginal Cultural Heritage Management and Protection. The educational programme developed supported learners to use technologies in cultural heritage management. Data were collected using community-developed fields for inclusion and culturally appropriate encryption of data.
Chairmen's perceptions of female board representation: a study on Nordic listed companies
Authors: Brunzell Tor , Liljeblom Eva 
Published: July 2014

Purpose– The purpose of this paper is to survey chairmen's perceptions of female board representation in five Nordic countries, focussing on whether the chairman's perception of board work is related to gender diversity, and on differences between high- and low-risk firms.Design/methodology/approach– The authors combine data from a questionnaire directed to the chairmen of the boards in Nordic listed companies with data on firm characteristics and board composition.Findings– The authors find that the chairmen (97.5 percent male) are significantly less satisfied with female board members as compared to male ones. The authors also find that firms with nomination committees have more gender diverse boards, as well as indications of a more positively perceived contribution of female representation in high-risk firms.Research limitations/implications– The study is restricted to perceptions of chairmen for listed Nordic firms. The low response rate of 20.1 percent is a severe limitation.Practical implications– The increasing practice of using nomination committees in the Nordic countries seems advantageous from gender balance perspective.Originality/value– The authors contribute to the literature on gender diversity in boards by providing results from a board intern perspective.
Presenting a model for safety program performance assessment using grey system theory
Authors: Omidvari Manouchehr , Lashgary Zeinab 
Published: July 2014

Purpose– The proposed model was capable of being used in both promoting safety performance level and evaluating and ranking safety units. The paper aims to discuss these issues.Design/methodology/approach– Managers must be able to determine positive impacts of safety programmes on the organisation and level of goal achievement and information access about performance of safety units. Since uncertain judgements of decision makers can be hardly estimated by numerical values, in this paper, based on grey system theory, a method was proposed for evaluating performance of safety units which was done using qualitative criteria of safety performance in an uncertain environment by one of the newest developed theory. This method used concept of grey theory to convert verbal variables into interval grey numbers; in the quantitative method, degree of grey possibility was imported.Findings– The results showed that the most important performance indicator in the field of safety in inter-urban transportation management included specialized safety training, safety auditing, hazard identification and risk evaluation, employees’ health monitoring, solid waste management and management review.Originality/value– This model could be extended for the whole safety issues and can be used as a simple and efficient method to evaluate performance of safety units in metro company of all the cities in order to determine their weaknesses and introduce the applied control strategies.
An exploration research of the independent college operation efficiency indicators based on DEA
Authors: Hong Lin , Chen Xue-Fen , Wang Yu , Li Qin 
Published: July 2014

Purpose– The purpose of this paper is to evaluate the teaching performance of the independent colleges by the method of data envelopment analysis (DEA) comprehensively.Design/methodology/approach– The DEA has become an available way to evaluate the similarity between input and output in several production department and non-production department. The similarity also is comparative efficiency because the way is based on goal linear programming in which there is inner layer of manufacture or fixed input increase output, and output which makes cost minimization of input minimum gets a comparative efficiency of decision making unit.Findings– The results show that an ideal teaching performance never relies on only way because the hysteresis effect of teaching outcome is known for a longer time. Just as the reason, some people argue about the performance evaluation. However, the teaching activity is a great investment. In face of few resources, the benefits of education are not easy to solve these problems. The key point is how to evaluate problems rather than giving up the evaluation.Originality/value– The paper is an exploration research of the teaching performance of independent colleges based on DEA, which not only means some theoretical value, but also means a strong realistic meaning.
Research on risk spread model of industrial chain
Authors: Chu Yanfeng , Dai Mei-Mei 
Published: July 2014

Purpose
– The industrial chain network is a complex system consisted by many members of the enterprise, and the complex relationship and the interaction with the external environment among the node enterprises and the existence of various uncertainty all increase the risk of the industry chain. The risk of some individual node enterprises will not only affect the normal operation but also spread the risk to other enterprises by network relationship because of their own mismanagement or deterioration of the external environment. The purpose of this paper is to make an attempt to establish the risk spread model of the industrial chain based on complex networks.

Design/methodology/approach
– By improving Lobos disaster diffuse model, the paper introduces two indexes: the risk spread range and the risk propagation velocity to measure of industrial chain risk communication effects, and design algorithm for industrial chain complex network structure. The risk spread range can be used to measure the coverage of the risk communication influence produced by the propagation enterprises in the industry chain and to analyse the risk spread breadth on the industrial chain network .The speed index of risk communication represents the total numbers of infection enterprises in unit simulation time.

Findings
– This paper proposes the universal industrial chain risk propagation model.

Originality/value
– Through proposed algorithm constructs industrial chain network, and enterprise class divide, the importance of the product chain enterprises in the industry chain is strengthened.
Development prediction of logistics industry in Henan province and its dynamic analysis
Authors: Huang Yimin 
Published: July 2014

Purpose
– The purpose of this paper is to establish a group of grey prediction models and relative degree model to study the characteristics and trend of the logistics industry development in Henan province scientifically. The study results can provide references for the development policy of the logistics industry in Henan province.

Design/methodology/approach
– The paper constructs grey prediction models and grey buffer operator models which are related to the distribution of logistics industry in Henan province, and selects prediction models by comparing model accuracy, and use them to forecast the development trend of logistics industry in future ten years of Henan province. Using the grey relative models, the paper analyses development dynamic and prospect which support the development of logistics industry, and provide some references for transferring the pattern of economic growth of Henan province, forming new economic growth point and formulating relevant policies. High prediction accuracy models are selected to forecast the future development trend of logistics industry in the next ten years.

Findings
– Results show that the modern logistics industry in Henan province has been a steady growth in overall, the main growth points of the logistics industry development in Henan province are roadway miles (km), roadway (100 million tonnes/km), freight turnover (100 million tonnes/km) and waterway (100 million tonnes), the growth points for the future development of logistics industry in Henan province are the roadway freight volume, roadway passenger volume and waterway freight volume.

Practical implications
– Regional economic competition has become an important index for measuring a country's economic development level. Logistics industry plays an important role in the regional economic development, such as promoting coordinated development of regional economy and upgrading industrial optimization, and playing a major role in industrial transfer. Hence, logistics industry, which is urgently needed to solve by the government, has become important forces for promoting the growth of economy and a basic pillar industries of regional economy.

Originality/value
– The paper presents the systematic results of development prediction of modern logistics industry in Henan province and its dynamic analysis by using grey systems theory, not only to predict the trend of the development of the logistics industry, also to analyse the future development of logistics industry in the leading power factors.
The status of traditional medicine and national medicine in different areas of the China in 2011 with grey clustering analysis
Authors: Duan Lizhong , Duan Gu-man , Lu Qi , Duan Jun , XIE Li-yun , MU Yuan 
Published: July 2014

Purpose
– The purpose of this paper is to improve the development of the Chinese traditional medicine (included the ethnic minority's medicine in China), it can raise the level of health for people, carry forward the culture of our nation, accelerate the economic development, promote social harmony and is very significant.

Design/methodology/approach
– In this paper, the factor which influences the development of the Chinese traditional medicine in these areas of China is analysed by the method called the grey relational analysis and grey clustering analysis.

Findings
– It is known that the comparative situation of each otherof the development of the Chinese traditional medicine in these areas. The causation is analysed.

Practical implications
– The behavioural mechanisms information which is effected by the traditional Chinese medicine (included ethnic minority medicine) is incomplete. Its inherent meaning is not clear. So it is reasonable to use the method called the grey relational analysis grey clustering analysis to study. Analysing the causes and giving countermeasures according to the results could propose some suggestions for the further development of Chinese medicine (including the national medicine) industry.

Originality/value
– The grey system theory was applied in medical management. The application of study results, the development of the Chinese traditional medicine (included the ethnic minority's medicine in China) is improved.
A pediatric robotic thumb exoskeleton for at-home rehabilitation
Authors: Aubin Patrick , Petersen Kelsey , Sallum Hani , Walsh Conor , Correia Annette , Stirling Leia 
Published: July 2014

Purpose– Pediatric disorders, such as cerebral palsy and stroke, can result in thumb-in-palm deformity greatly limiting hand function. This not only limits children's ability to perform activities of daily living but also limits important motor skill development. Specifically, the isolated orthosis for thumb actuation (IOTA) is 2 degrees of freedom (DOF) thumb exoskeleton that can actuate the carpometacarpal (CMC) and metacarpophalangeal (MCP) joints through ranges of motion required for activities of daily living. The paper aims to discuss these issues.Design/methodology/approach– IOTA consists of a lightweight hand-mounted mechanism that can be secured and aligned to individual wearers. The mechanism is actuated via flexible cables that connect to a portable control box. Embedded encoders and bend sensors monitor the 2 DOF of the thumb and flexion/extension of the wrist. A linear force characterization was performed to test the mechanical efficiency of the cable-drive transmission and the output torque at the exoskeletal CMC and MCP joints was measured.Findings– Using this platform, a number of control modes can be implemented that will enable the device to be controlled by a patient to assist with opposition grasp and fine motor control. Linear force and torque studies showed a maximum efficiency of 44 percent, resulting in a torque of 2.39±1.06 in.-lbf and 0.69±0.31 in.-lbf at the CMC and MCP joints, respectively.Practical implications– The authors envision this at-home device augmenting the current in-clinic and at-home therapy, enabling telerehabilitation protocols.Originality/value– This paper presents the design and characterization of a novel device specifically designed for pediatric grasp telerehabilitation to facilitate improved functionality and somatosensory learning.
Characterizing the human-robot haptic dyad in robot therapy of stroke survivors
Authors: De Santis Dalia , Zenzeri Jacopo , Casadio Maura , Masia Lorenzo , Squeri Valentina , Morasso Pietro 
Published: July 2014

Purpose
– The working hypothesis, on which this paper is built, is that it is advantageous to look at protocols of robot rehabilitation in the general context of human-robot interaction in haptic dyads. The purpose of this paper is to propose a new method to detect and evaluate an index of active participation (AC index), underlying the performance of robot-assisted movements. This is important for avoiding the slacking phenomenon that affects robot therapy.

Design/methodology/approach
– The evaluation of the AC index is based on a novel technique of assistance which does not use constant or elastic forces but trains of small force impulses, with amplitude adapted to the level of impairment and a frequency of 2 Hz, which is suggested by recent results in the field of intermittent motor control. A preliminary feasibility test of the proposed method was carried out during a haptic reaching task in the absence of visual feedback, for a group of five stroke patients and an equal group of healthy subjects.

Findings
– The AC index appears to be stable and sensitive to training in both populations of subjects.

Originality/value
– The main original element of this study is the proposal of the new AC index of voluntary control associated with the new method of pulsed haptic interaction.