bluuebunny/crossref_metadata_2025_split huggingface dataset:
Honking Helps Overcome the Driving Too Slowly Problem in Driving Simulators
Authors: Jeong Heejin , Green Paul 
Published: October 2015

In driving simulators, subjects sometimes drive more slowly than they would on real roads when not attending to driving. To address this problem, in two experiments, groups of 24 subjects drove through 138 intersections with green (53 %), yellow (36 %), or red lights (11 %). The speed limit was 35 mi/hr. In the second experiment, the following vehicle honked as needed. The number of honks per subject varied from 0 to 6 for driving too slowly (less than 25 mi/hr) and 0 to 8 for delayed responses when a traffic light changed from red to green. Older drivers received 2.4 times more honks than younger drivers. Within 5 s after the following vehicle honked between intersections, the mean speed driven increased by 5 mi/hr. Similarly, with honking, the speed 5 s after the light changed increased by 8 mi/hr, both changes that lead to more realistic driving.
Translating Usability Test Data into Client-Ready Findings and Recommendations
Authors: Davis Kristen , Douglas Dana 
Published: October 2015

In recent years, user experience research (particularly usability testing) has become increasingly widespread. One reason for the increased popularity is the scrutiny many highly-publicized websites receive as a result of a poor user experience. Organizations are now focusing more on user experience and are seeking researchers to conduct usability testing, perhaps without fully appreciating the type of data this research can provide and how that data should be interpreted. We will identify and discuss best practices for researchers who are collecting, analyzing, and presenting usability test data to help them provide clear, actionable findings and recommendations that clients can understand. We discuss what types of data can be collected depending on the product being evaluated, what conclusions can be gleaned from different types of data, and which tools can be used to make the analysis more efficient.
Patient Outcomes and Predictors of Success After Revision Anterior Cruciate Ligament Reconstruction
Authors: Johnson William R. , Makani Amun , Wall Andrew J. , Hosseini Ali , Hampilos Perry , Li Guoan , Gill Thomas J. 
Published: October 2015

Background: Patient outcomes and predictors of success after revision anterior cruciate ligament (ACL) reconstruction are currently limited in the literature. Existing studies either have a small study size or are difficult to interpret because of the multiple surgeons involved in the care of the study sample. Purpose: To determine patient outcomes and predictors of success or failure after a single-stage revision ACL reconstruction by a single fellowship-trained senior surgeon at a single institution. Study Design: Case series; Level of evidence, 4. Methods: A total of 78 patients who underwent revision ACL reconstruction by a single surgeon from 2010 to 2014 were contacted and available for follow-up. The mean time from revision procedure to follow-up was 52 months. Those patients who were able to participate in the study sent in a completed Tegner activity level scale, International Knee Documentation Committee (IKDC) Subjective Knee Evaluation Form, and IKDC Current Health Assessment Form. The patients’ medical records were also thoroughly reviewed. Results: Five patients had subsequent failure after revision surgery. The median Tegner score was 6 at follow-up, and the mean subjective IKDC score was 72.5. There was no statistically significant difference in outcome scores when comparing revision graft type, body mass index, sex, need for bone grafting, and time from failure to revision. Patients with failures after primary ACL reconstruction secondary to a traumatic event were found to have statistically significantly higher IKDC scores (mean, 76.6) after revision when compared with nontraumatic failures (mean, 67.1), even when controlling for confounders ( P < .017). Conclusion: Revision ACL reconstruction is effective in improving patient activity levels and satisfaction. However, the subjective IKDC results are quite variable and likely based on multiple factors. Patients with traumatic injuries contributing to graft failure after primary ACL reconstruction had a statistically significantly, although not clinically significant, higher IKDC score after revision surgery compared with nontraumatic failures. These data may be useful when counseling a patient on whether to pursue revision ACL reconstruction surgery.
Primary Care Clinics and Accountable Care Organizations
Authors: Ortiz Judith , Tang Chiung-Ya , Lin Yi-Ling , Masri Maysoun D. 
Published: October 2015

Background: The Accountable Care Organization (ACO) is one of the new models of health care delivery in the United States. To date, little is known about the characteristics of health care organizations that have joined ACOs. We report on the findings of a survey of primary care clinics, the objective of which was to investigate the opinions of clinic management about participation in ACOs and the characteristics of clinic organizational structure that may contribute to joining ACOs or be willing to do so. Methods: A 27-item survey questionnaire was developed and distributed by mail in 3 annual waves to all Rural Health Clinics (RHCs) in 9 states. Two dependent variables—participation in ACOs and willingness to join ACOs—were created and analyzed using a generalized estimating equation approach. Results: A total of 257 RHCs responded to the survey. A small percentage (5.2%) of the respondent clinics reported that they were participating in ACOs. Rural Health Clinics in isolated areas were 78% less likely to be in ACOs (odds ratio = 0.22, P = .059). Nonprofit RHCs indicated a higher willingness to join an ACO than for-profit RHCs (B = 1.271, P = .054). There is a positive relationship between RHC size and willingness to join an ACO (B = 0.402, P = .010). Conclusion: At this early stage of ACO development, many RHC personnel are unfamiliar with the ACO model. Rural providers’ limited technological and human resources, and the lack of ACO development in rural areas, may delay or prevent their participation in ACOs.
Low ADAMTS13 activity is associated with an increased risk of ischemic stroke
Authors: Sonneveld Michelle A. H. , de Maat Moniek P. M. , Portegies Marileen L. P. , Kavousi Maryam , Hofman Albert , Turecek Peter L. , Rottensteiner Hanspeter , Scheiflinger Fritz , Koudstaal Peter J. , Ikram M. Arfan , Leebeek Frank W. G. 
Published: October 2015

Key Points
Low ADAMTS13 activity is associated with ischemic stroke. ADAMTS13 activity improved the accuracy of ischemic stroke risk predictions beyond the traditional risk factors.
TALEN-mediated genetic inactivation of the glucocorticoid receptor in cytomegalovirus-specific T cells
Authors: Menger Laurie , Gouble Agnes , Marzolini Maria A. V. , Pachnio Annette , Bergerhoff Katharina , Henry Jake Y. , Smith Julianne , Pule Martin , Moss Paul , Riddell Stanley R. , Quezada Sergio A. , Peggs Karl S. 
Published: October 2015

Key Points
The GR gene can be inactivated in Streptamer-selected CMV-specific CD8+ T cells using TALEN. The GR gene inactivation endows T cells with resistance to the immunosuppressive effects of corticosteroids in vitro and in vivo.
European structural funds during the crisis: evidence from Southern Italy
Authors: Ciani Emanuele , de Blasio Guido 
Published: October 2015

Abstract
We investigate the effectiveness of European Structural Funds on employment, population and house prices in 325 Local Labor Markets (LLM) located in Southern Italy. We exploit the variability in disbursements between 2007 and 2013 and estimate the impact of the interventions by allowing for LLM-specific fixed features and LLM-specific time trends. We find that the ability of these funds to offset the negative consequences of the economic crisis seems to have been limited.
Public Discourse and Models of Womanhood in Yucatán, 1870–1902
Authors: Campos García Melchor 
Published: October 2015

Abstract
In 1870, the women's association La Siempreviva established a school for girls and a journal of the same name; it both exposed the gender gap in educational opportunities and championed women's emancipation, which challenged patriarchal norms. Yet by 1872, La Siempreviva had abandoned its journal and the public debate on women's emancipation. While La Siempreviva directed the Instituto Literario de Niñas in 1877–1879 and in 1886–1902, men from various social sectors publicly discussed multiple models of womanhood, ranging from the Catholic Marian ideal to the conservative “angel of the house” and the model of Hypatia promoted by Protestants and freethinkers. This article analyzes La Siempreviva's drive to reform traditional gender roles and expand women's rights while tracing how this bargaining resulted in a new model of gender during the Porfiriato marked by the double shift.
“To Fight These Powerful Trusts and Free the Medical Profession”: Medicine, Class Formation, and Revolution in Cuba, 1925–1935
Authors: Rodriguez Daniel A. 
Published: October 2015

AbstractThis essay explores the radicalization of the Cuban medical class in the context of the economic and political crises of the late 1920s and early 1930s. Organized under the Cuban Medical Federation, physicians targeted Havana's Spanish-run hospital system for its low wages and unfair practices. During these years, an active campaign to overthrow the dictatorship of Gerardo Machado influenced a new generation of young doctors and medical students, who pushed the federation to link its class interests to the broader political and social problems of the Cuban people. I argue that the social forces unleashed with the 1933 fall of Machado transformed the medical class, leading to increased support for the radical reconfiguration of Cuban medical practice. After a painful medical strike, the failure of international mediation efforts, and increased government hostility to the federation, the Cuban medical class increasingly pushed for the radical expansion of the public medical sector.
Exploring the HIFs, buts and maybes of hypoxia signalling in disease: lessons from zebrafish models
Authors: Elks Philip M. , Renshaw Stephen A. , Meijer Annemarie H. , Walmsley Sarah R. , van Eeden Fredericus J. 
Published: October 2015

ABSTRACTA low level of tissue oxygen (hypoxia) is a physiological feature of a wide range of diseases, from cancer to infection. Cellular hypoxia is sensed by oxygen-sensitive hydroxylase enzymes, which regulate the protein stability of hypoxia-inducible factor α (HIF-α) transcription factors. When stabilised, HIF-α binds with its cofactors to HIF-responsive elements (HREs) in the promoters of target genes to coordinate a wide-ranging transcriptional programme in response to the hypoxic environment. This year marks the 20th anniversary of the discovery of the HIF-1α transcription factor, and in recent years the HIF-mediated hypoxia response is being increasingly recognised as an important process in determining the outcome of diseases such as cancer, inflammatory disease and bacterial infections. Animal models have shed light on the roles of HIF in disease and have uncovered intricate control mechanisms that involve multiple cell types, observations that might have been missed in simpler in vitro systems. These findings highlight the need for new whole-organism models of disease to elucidate these complex regulatory mechanisms. In this Review, we discuss recent advances in our understanding of hypoxia and HIFs in disease that have emerged from studies of zebrafish disease models. Findings from such models identify HIF as an integral player in the disease processes. They also highlight HIF pathway components and their targets as potential therapeutic targets against conditions that range from cancers to infectious disease.
Controlling Partnering Relations In Construction Operations Using Fuzzy Reasoning
Authors: Radziszewska-Zielina E. , Szewczyk B. 
Published: October 2015

AbstractThe article presents the use of the Mamdani fuzzy reasoning model to develop a proposal of a system controlling partnering relations in construction projects. The system input variables include: current assessments of particular partnering relation parameters, the weights of these parameters' impact on time, cost, quality and safety of implementation of construction projects, as well as the importance of these project assessment criteria for its manager. For each of the partnering relation parameters, the project’s manager will receive control recommendations. Moreover, the parameter to be improved first will be indicated. The article contains a calculation example of the system's operations.
The Evaluation Of Algorithms For Determination Of The Reliability Index
Authors: Dudzik A. , Radoń U. 
Published: October 2015

AbstractThe study deals with stability and dynamic problems in bar structures using a probabilistic approach. Structural design parameters are defined as deterministic values and also as random variables, which are not correlated. The criterion of structural failure is expressed by the condition of non-exceeding the admissible load multiplier and condition of non-exceeding the admissible vertical displacement. The Hasofer-Lind index was used as a reliability measure. The primary research tool is the FORM method. In order to verify the correctness of the calculations Monte Carlo and Importance Sampling methods were used. The sensitivity of the reliability index to the random variables was defined. The limit state function is not an explicit function of random variables. This dependence was determined using a numerical procedure, e.g. the finite element methods. The paper aims to present the communication between the STAND reliability analysis program and the KRATA and MES3D external FE programs.
Third-order differential subordination
and superordination involving
a fractional operator
Authors: Ibrahim Rabha W. , Ahmad Muhammad Zaini , Al-Janaby Hiba F. 
Published: October 2015

Abstract
The third-order differential subordination and the corresponding differential superordination problems for
a new linear operator convoluted the fractional integral operator with the Carlson-Shaffer operator, are investigated in
this study. The new operator satisfies the required first-order differential recurrence (identity) relation. This property
employs the subordination and superordination methodology. Some classes of admissible functions are determined,
and these significant classes are exploited to obtain fractional differential subordination and superordination results.
The new third-order differential sandwich-type outcomes are investigated in subsequent research.
A parametric approach to kinship hypothesis testing using identity-by-descent parameters
Authors: García-Magariños Manuel , Egeland Thore , López-de-Ullibarri Ignacio , Hjort Nils L. , Salas Antonio 
Published: October 2015

AbstractThere is a large number of applications where family relationships need to be determined from DNA data. In forensic science, competing ideas are in general verbally formulated as the two hypotheses of a test. For the most common paternity case, the null hypothesis states that the alleged father is the true father against the alternative hypothesis that the father is an unrelated man. A likelihood ratio is calculated to summarize the evidence. We propose an alternative framework whereby a model and the hypotheses are formulated in terms of parameters representing identity-by-descent probabilities. There are several advantages to this approach. Firstly, the alternative hypothesis can be completely general. Specifically, the alternative does not need to specify an unrelated man. Secondly, the parametric formulation corresponds to the approach used in most other applications of statistical hypothesis testing and so there is a large theory of classical statistics that can be applied. Theoretical properties of the test statistic under the null hypothesis are studied. An extension to trios of individuals has been carried out. The methods are exemplified using simulations and a real dataset of 27 Spanish Romani individuals.
Detektion von Lufteinschlüssen bei der Kleberaupenapplikation
Authors: Kölmel Adrian , Bareis Jan , Stefan Lucian , Heinrich Andreas , Lanza Gisela 
Published: October 2015

Zusammenfassung
Die Klebetechnik gewinnt als zukunftsträchtige, variabel
einsetzbare Fügetechnik immer mehr an Bedeutung. Um Ausschuss zu
vermeiden und Prozesse steuern zu können, müssen
zerstörungsfreie Qualitätssicherungsmaßnahmen in die
Prozessketten integriert werden. Ultraschallbasierte Messkonzepte
bieten hierfür eine mögliche Lösung zur Detektion von
qualitätskritischen Lufteinschlüssen bei der Applikation von
Kleberaupen.
Investigation of the heat transfer in a square microchannel with Al2O3-H2O nanofluids
Authors: Irwansyah Ridho , Massing Julian , Cierpka Christian , Kähler Christian J. 
Published: October 2015

Abstract
The progressing miniaturisation and increasing power demand of
microelectronic devices require efficient cooling systems to avoid
thermal damage. Future cooling systems have to be capable of dealing
with heat loads of more than 200 W/cm2, at small temperature
differences. However, the convective heat transfer in microchannels is
limited due to the laminar flow regime. Nanofluids, i. e. fluids with
suspended particles of nanometer size, have been shown to enhance the
heat transfer. Nevertheless, their potential was recently
controversially discussed in the literature. Therefore, reliable
experimental heat transfer investigations are necessary to understand
the underlying physical phenomena and help to establish design rules
for future microelectronic cooling systems. For this reason the aim of
the current study was to design and test a platform for the
characterization of the fluid flow and the heat transfer in a straight
microchannel. The heat transfer using pure water and water with
30–60 nm Al2O3 nanoparticles were investigated at two
different volume concentrations, 1% and 2.5% and
Reynolds numbers ranging from 70 to 300. The results imply that the
experimental platform allows for reliable and reproducible
measurements of heat transfer and its sensitivity to the appropriated
fluid and the flow properties. It could be shown that the heat
transfer coefficient can be enhanced by up to 5.5% using
2.5% water-Al2O3 nanofluids compared to distilled
water.
Modular ultrasound platform for flow mapping in magnetohydrodynamics
Authors: Mäder Kevin , Nauber Richard , Beyer Hannes , Klaß Arne , Thieme Norman , Büttner Lars , Czarske Jürgen 
Published: October 2015

Abstract
Flow control based on time-dependent magnetic fields is used in
various industrial processes involving liquid metals, i. e. during the
solidification process of silicon to improve the quality and
efficiency of wafers. In order to investigate the interactions between
spatiotemporal-varying magnetic fields and conductive fluids numerical
simulations are performed. The numerical models are verified by model
experiments with opaque low-melting alloys. A suitable measurement
technique for flow mapping in such model experiments is ultrasound
Doppler velocimetry. In contrast to conventional systems employing
transducers with fixed sound field our approach is to use a phased
array with the ability to focus and steer its acoustic field. We
present the Phased Array Ultrasound Doppler Velocimeter (PAUDV) for
flow mapping in magnetohydrodynamics. With its custom host software
for control and signal processing experiments that are flexible
regarding the experimental setup can be defined.
The Effects of Political Socialization Programmes: The Youth Parliament Experience in Brazil
Authors: Fuks Mario 
Published: October 2015

AbstractThis article investigates the changes that civic education programmes produce in their participants, and offers an integrated view of the determinants as well as the resulting effect patterns. The main conclusions are: 1) values are more resistant to change than motivation, political knowledge, and attitudes towards political institutions; 2) cognitive gains and attitudinal changes are more likely to occur (and with greater intensity) when the object belongs to the programme’s environment; 3) the effects on political participation do not occur in the present, but the data indicates a tendency towards greater participation later in adult life; 4) the programme’s quality and the participant’s motivation stand out because, usually, they affect the influence of other factors. The object of this study is the Mineiro Youth Parliament in its 2008 edition. The research design follows the logic of quasi-experimental research [Campbell, D. and J. Stanley (1979)
Typical and Atypical Development of Functional Connectivity in the Face Network
Authors: Song Yiying , Zhu Qi , Li Jingguang , Wang Xu , Liu Jia 
Published: October 2015

Extensive studies have demonstrated that face recognition performance does not reach adult levels until adolescence. However, there is no consensus on whether such prolonged improvement stems from development of general cognitive factors or face-specific mechanisms. Here, we used behavioral experiments and functional magnetic resonance imaging (fMRI) to evaluate these two hypotheses. With a large cohort of children (n= 379), we found that the ability of face-specific recognition in humans increased with age throughout childhood and into late adolescence in both face memory and face perception. Neurally, to circumvent the potential problem of age differences in task performance, attention, or cognitive strategies in task-state fMRI studies, we measured the resting-state functional connectivity (RSFC) between the occipital face area (OFA) and fusiform face area (FFA) in human brain and found that the OFA-FFA RSFC increased until 11–13 years of age. Moreover, the OFA-FFA RSFC was selectively impaired in adults with developmental prosopagnosia (DP). In contrast, no age-related changes or differences between DP and normal adults were observed for RSFCs in the object system. Finally, the OFA-FFA RSFC matured earlier than face selectivity in either the OFA or FFA. These results suggest the critical role of the OFA-FFA RSFC in the development of face recognition. Together, our findings support the hypothesis that prolonged development of face recognition is face specific, not domain general.SIGNIFICANCE STATEMENTThere is long-standing debate on whether the prolonged age-related improvement in face recognition performance stems from development of general cognitive factors or face-specific mechanisms. Here, we provide novel evidence for protracted development of face-specific mechanisms. Specifically, the resting-state functional connectivity (RSFC) between the fusiform face area and occipital face area, two core brain areas in the face network, increased until 11–13 years of age and was selectively impaired in adults with developmental prosopagnosia. These results suggested the importance of the face network RSFC in the development of face recognition. Our study invites a broader investigation of whether the development of other cognitive abilities is similarly guided by the development of connectivity within the corresponding neural networks.