bluuebunny/crossref_metadata_2025_split huggingface dataset:
CO2 wettability of caprocks: Implications for structural storage capacity and containment security
Authors: Iglauer Stefan , Al‐Yaseri Ahmed Zarzor , Rezaee Reza , Lebedev Maxim 
Published: September 2015

AbstractStructural trapping, the most important CO2 geostorage mechanism during the first decades of a sequestration project, hinges on the traditional assumption that the caprock is strongly water wet. However, this assumption has not yet been verified; and it is indeed not generally true as we demonstrate here. Instead, caprock can be weakly water wet or intermediate wet at typical storage conditions; and water wettability decreases with increasing pressure or temperature. Consequently, a lower storage capacity can be inferred for structural trapping in such cases.
PV dynamics: The role of small‐scale turbulence, submesoscales and mesoscales
Authors: Canuto V. M. 
Published: September 2015

AbstractThe diabatic and frictional components of the PV fluxes J in the Haynes‐McIntyre conservation law have been studied with physical arguments, scaling laws and numerical simulations. We suggest a procedure that expresses J in terms of buoyancy and momentum fluxes by small‐scale turbulence SS, submesoscales SM and mesoscales M. We employ the latest parameterizations of these processes and derive analytic expressions of the diabatic and frictional J fluxes for arbitrary wind stresses; we then consider the case of an Ekman flow. Small‐scale turbulence: at z=0, down and up‐front winds contribute equally to the frictional component of J while the diabatic component is much larger than that of mesoscales. Submesoscales: the geostrophic contributions to both diabatic and frictional J have the same sign while the wind contributions have opposite signs. Their magnitude depends on the SM kinetic energy which is derived in terms of large‐scale parameters. Comparison with numerical simulations is limited since the ones available resolve M but not SM. They concluded that the field patterns of the J fluxes are very similar to those obtained without resolving M, in agreement with the present analysis; a second conclusion that the diabatic component of J is an order of magnitude larger than the frictional one, is also in accordance with present results. When wind stresses are accounted for, down‐front winds lower PV and up‐front winds increase it. The changes in Hoskins' criterion for the onset of symmetric instabilities are discussed.
Development and steady states of transverse dunes: A numerical analysis of dune pattern coarsening and giant dunes
Authors: Gao Xin , Narteau Clément , Rozier Olivier 
Published: September 2015

AbstractWe investigate the development and steady states of transverse dunes for ranges of flow depths and velocities using a cellular automaton dune model. Subsequent to the initial bed instability, dune pattern coarsening is driven by bed form interactions. Collisions lead to two types of coalescence associated with upstream or downstream dominant dunes. In addition, a single collision‐ejection mechanism enhances the exchange of mass between two adjacent bed forms (throughpassing dunes). The power law increases in wavelength and amplitude exhibit the same exponents, which are independent of flow properties. Contrary to the wavelength, dune height is limited not only by flow depth but also by the strength of the flow. Superimposed bed forms may propagate and continuously destabilize the largest dunes. We identify three classes of steady state transverse dune fields according to the periodicity in crest‐to‐crest spacing and the mechanism of size limitation. In all cases, the steady state is reached and maintained through the dynamic equilibrium between flow strength and dune aspect ratio. In the limit of low flow strength, where it becomes the primary factor of size limitation, the bed shear stress in the dune trough regions is close to its critical value for motion inception. Comparisons with natural dune fields suggest that many of them may have reached a steady state. Finally, we infer that the sedimentary patterns in the model may be used to bring new constraints on the development of modern and ancient dune fields.
Analysis of discontinuities across thin inhomogeneities, groundwater/surface water interactions in river networks, and circulation about slender bodies using slit elements in the Analytic Element Method
Authors: Steward David R. 
Published: September 2015

AbstractGroundwater and surface water contain interfaces across which hydrologic functions are discontinuous. Thin elements with high hydraulic conductivity in a porous media focus groundwater, which flows through such inhomogeneities and causes an abrupt change in stream function across their interfaces, and elements with low conductivity retard flow with discontinuous head. Base flow interactions at the interface between groundwater and surface water transport water between these stores and generate a discontinuous normal component of flow. Thin objects in surface water with Kutta condition generate circulation by the discontinuous tangential component of flow across their interface. These discontinuities across hydrologic interfaces are quantified and visualized using the Analytic Element Method, where slit elements are formulated using the Joukowsky transformation with Laurent series and new influence functions to represent sinks and circulation, and methods are developed for these applications expressing discontinuities as Fourier series. The specific geometries illustrate solutions for a randomly generated heterogeneous porous media with nonintersecting inhomogeneities, for groundwater/surface water interaction in a synthetic river network, and for a slender body with geometry similar to the wings of the Wright Brothers. The mathematical details are reduced to series solutions and matrix multiplications, which are easily extensible to other geometries and applications.
American College of Rheumatology/Spondylitis Association of America/Spondyloarthritis Research and Treatment Network 2015 Recommendations for the Treatment of Ankylosing Spondylitis and Nonradiographic Axial Spondyloarthritis
Authors: Ward Michael M. , Deodhar Atul , Akl Elie A. , Lui Andrew , Ermann Joerg , Gensler Lianne S. , Smith Judith A. , Borenstein David , Hiratzka Jayme , Weiss Pamela F. , Inman Robert D. , Majithia Vikas , Haroon Nigil , Maksymowych Walter P. , Joyce Janet , Clark Bruce M. , Colbert Robert A. , Figgie Mark P. , Hallegua David S. , Prete Pamela E. , Rosenbaum James T. , Stebulis Judith A. , Van Den Bosch Filip , Yu David T. Y. , Miller Amy S. , Reveille John D. , Caplan Liron 
Published: September 2015

ObjectiveTo provide evidence‐based recommendations for the treatment of patients with ankylosing spondylitis (AS) and nonradiographic axial spondyloarthritis (SpA).MethodsA core group led the development of the recommendations, starting with the treatment questions. A literature review group conducted systematic literature reviews of studies that addressed 57 specific treatment questions, based on searches conducted in OVID Medline (1946–2014), PubMed (1966–2014), and the Cochrane Library. We assessed the quality of evidence using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) method. A separate voting group reviewed the evidence and voted on recommendations for each question using the GRADE framework.ResultsIn patients with active AS, the strong recommendations included use of nonsteroidal antiinflammatory drugs (NSAIDs), use of tumor necrosis factor inhibitors (TNFi) when activity persists despite NSAID treatment, not to use systemic glucocorticoids, use of physical therapy, and use of hip arthroplasty for patients with advanced hip arthritis. Among the conditional recommendations was that no particular TNFi was preferred except in patients with concomitant inflammatory bowel disease or recurrent iritis, in whom TNFi monoclonal antibodies should be used. In patients with active nonradiographic axial SpA despite treatment with NSAIDs, we conditionally recommend treatment with TNFi. Other recommendations for patients with nonradiographic axial SpA were based on indirect evidence and were the same as for patients with AS.ConclusionThese recommendations provide guidance for the management of common clinical questions in AS and nonradiographic axial SpA. Additional research on optimal medication management over time, disease monitoring, and preventive care is needed to help establish best practices in these areas.
A systematic study on the effects of doping agents on polypyrrole coating of fabrics
Authors: Varesano Alessio , Belluati Andrea , Sanchez Ramirez Diego Omar , Carletto Riccardo Andrea , Vineis Claudia , Tonetti Cinzia , Bianchetto Songia Michela , Mazzuchetti Giorgio 
Published: September 2015

ABSTRACTPolypyrrole is widely used as coating to produce electrically conductive textiles. Counter‐ions (i.e. doping agents) were embedded in polypyrrole to improve electrical conductivity. Good electrical performances are required for several applications, such as microwave attenuation/electro‐magnetic interference shielding, heat generation, electro‐static discharge protection, sensing, and energy storage. In this work, a systematic study was carried out on the effects of doping agents in coating cotton fabrics with a thin polypyrrole layer. A total of 11 compounds were selected and compared as counter‐ions. The electrical performances of the coated fabrics were assessed with measures of electrical conductivity. Moreover, evenness and morphology of the resulting polypyrrole layer were discussed. As the final result, the best performances in terms of electrical conductivity (i.e. low surface resistivity) were measured using on dicyclohexyl sulfosuccinate, 2,6‐naphthalenedisulfonate or 1,5‐naphthalenedisulfonate as doping agents. The weight increases after polypyrrole deposition on the fabrics were greater than 15% and polypyrrole deposited on the fibers as a uniform film. © 2015 Wiley Periodicals, Inc. J. Appl. Polym. Sci.2016,132, 42831.
Geometric Morphometrics: Does the Appearance of the Septal Aperture Depend on the Shape of Ulnar Processes?
Authors: Kubicka Anna Maria , Myszka Anna , Piontek Janusz 
Published: September 2015

ABSTRACTMany theories have been suggested to explain the etiology of septal apertures (SA) of the humerus. The influence of genes, the size of ulnar processes, joint laxity, and bone robusticity, have been discussed; however, the problem has not yet been solved. The main aim of this study was to examine the influence of ulnar and humeri shape on septal aperture formation, using geometric morphometric analyses. Skeletal material from an early‐mediaeval cemetery located in Western Poland was used. The material comprised two groups: (1) ulnae and humeri with septal apertures, (2) ulnae and humeri without septal apertures. From a CT image, three‐dimensional reconstructions were obtained for all bones. Then, 25 landmarks were distributed on each proximal end of the ulnae and 30 landmarks on the distal ends of the humeri. Shape differences between ulnae in joints with and without SA were significant for the left and right sides of the body. The shapes of the left and right distal ends of humeri with SA differed significantly from those without SA. Similar results were obtained for the right side of the body. Ulnae from joints with SA were characterized by a more pronounced olecranon process, a smaller articulated coronoid process and a more tightly curved trochlear notch than ulnae from joints without SA. Humeri with SA included wider and deeper olecranon fossae and smaller and less curved articular surfaces. These results partly coincide with the results of other research indicating the influence of olecranon processes on lamina perforation. Anat Rec, 298:2030–2038, 2015. © 2015 Wiley Periodicals, Inc.
Selective inhibition of dopamine‐beta‐hydroxylase enhances dopamine release from noradrenergic terminals in the medial prefrontal cortex
Authors: Devoto Paola , Flore Giovanna , Saba Pierluigi , Frau Roberto , Gessa Gian L. 
Published: September 2015

AbstractIntroductionDisulfiram has been claimed to be useful in cocaine addiction therapy, its efficacy being attributed to dopamine‐beta‐hydroxylase (DBH) inhibition. Our previous results indicate that disulfiram and the selective DBH inhibitor nepicastat increase extracellular dopamine (DA) in the rat medial prefrontal cortex (mPFC), and markedly potentiated cocaine‐induced increase. Concomitantly, in rats with cocaine self‐administration history, cocaine‐seeking behavior induced by drug priming was prevented, probably through overstimulation of D1 receptors due to the DA increase. The present research was aimed at studying the neurochemical mechanisms originating the enhanced DA release.MethodsNoradrenergic system ablation was attained by intracerebroventricular (i.c.v.) administration of the neurotoxin anti‐DBH‐saporin (aDBH‐sap). DA, noradrenaline (NA), and DOPAC were assessed by HPLC after ex vivo tissue extraction or in vivo microdialysis. Control and denervated rats were subjected to microdialysis in the mPFC and caudate nucleus to evaluate the effect of nepicastat–cocaine combination on extracellular DA levels and their regulation by α2‐adrenoceptors.ResultsFifteen days after neurotoxin or its vehicle administration, tissue and extracellular NA were reduced to less than 2% the control value, while extracellular DA was increased by approximately 100%. In control rats, nepicastat given alone and in combination with cocaine increased extracellular DA by about 250% and 1100%, respectively. In denervated rats, nepicastat slightly affected extracellular DA, while in combination with cocaine increased extracellular DA by 250%. No differences were found in the caudate nucleus. Clonidine almost totally reversed the extracellular DA elevation produced by nepicastat–cocaine combination, while it was ineffective in denervated rats.ConclusionsThis research shows that the increase of extracellular DA produced by nepicastat alone or in combination with cocaine was prevented by noradrenergic denervation. The results indicate that nepicastat enhances DA release from noradrenergic terminals supposedly by removing NA from α2‐autoreceptors. In addition to the inhibition of DA uptake, the latter mechanism may explain the synergistic effect of cocaine on nepicastat‐induced DA release.
Tools and methodologies for teaching robotics in computer science & engineering studies
Authors: Berenguel Manuel , Rodríguez Francisco , Moreno José Carlos , Guzmán José Luis , González Ramón 
Published: September 2015

ABSTRACTThis work presents a teaching experience of Robotics in Computer Science & Engineering studies at the University of Almería (Spain). The teaching methodology is mainly based on the use of ICT. In particular, interactive software tools, virtual and remote laboratories, and an e‐learning content management are used. Such technologies have significantly helped to improve the learning ability of the students. A discussion and feedback from students are presented to show the result of this educational approach. © 2015 Wiley Periodicals, Inc. Comput Appl Eng Educ 24:202–214, 2016; View this article online at wileyonlinelibrary.com/journal/cae; DOI 10.1002/cae.21698
The perilipin‐2 (adipophilin) coat of cytosolic lipid droplets is regulated by an Arf1‐dependent mechanism in HC11 mouse mammary epithelial cells
Authors: Pauloin Alain , Adenot Pierre , Hue‐Beauvais Catherine , Chanat Eric 
Published: September 2015

AbstractThe cytosolic lipid droplets (cLDs) store excess intracellular lipids, and perilipin‐2 is believed to protect cLDs from degradation. Here, we investigated the role of the small G‐protein Arf1 and the proteasome in the fates of perilipin‐2 and cLDs. In oleate‐loaded cells, upon brefeldin A (BFA) treatment, perilipin‐2 remained associated with cLDs for at least 30 min before significant release, and proteasomal degradation‐mediated decrease was observed. Interestingly, the cLD population did not mimic the decline in perilipin‐2. We tested several chemical modulators of regulators of Arf1 activity on the association of perilipin‐2 with cLDs. QS11 and Exo2 accelerated the reduction in perilipin‐2, although less than BFA. In contrast, Exo1 unexpectedly slowed down its degradation. Correlatively, BFA, QS11, and Exo2 enhanced the dissociation of perilipin‐2 from cLDs, whereas Exo1 inhibited it. There was a synergistic effect of BFA with Exo2 and QS11, and of Exo2 with QS11, whereas Exo1 antagonized the effect of BFA without affecting that of Exo2 or QS11. We concluded that the Arf1 complex regulates the association of perilipin‐2 with cLDs. Additionally, MG132 and BFA modified the number of cLDs over a relatively short period.
Clinical outcomes in real‐world patients with bifurcation lesions receiving Xience V everolimus‐eluting stents: Four‐year results from the Xience V USA study
Authors: Hermiller James B. , Applegate Robert J. , Baird Colleen , Butler Michael M. , Rutledge David , Wang Jin , Kakarala Kalyan , Krucoff Mitchell W. , Sudhir Krishnankutty 
Published: September 2015

BackgroundThe Xience V USA Study demonstrated safety and efficacy of the XIENCE V® everolimus‐eluting stent (EES) in a large, prospective study of a real‐world, unselected patient population. There is limited long‐term data regarding EES performance in high risk patients with bifurcation lesions (BIF). The objective of this analysis was to evaluate the long‐term safety and effectiveness of EES in patients with BIF from the XIENCE V USA study.MethodsThe Xience V USA Study was a single arm, prospective, multicenter, real‐world study (n = 5,054) undergoing PCI with EES. Baseline data and clinical outcomes at 4 years were evaluated in the subgroup of patients with ≥ 1 BIF who did not undergo a staged procedure. Co‐primary endpoints were ARC definite/probable stent thrombosis and a composite of cardiac death and ARC‐defined myocardial infarction (MI). Endpoints were adjudicated by an independent CEC.ResultsOf 4,768 patients who did not undergo a staged procedure, there were 511 (10.7%) patients with BIF and 4,257 (89.3%) patients without BIF. Follow‐up data was available in 4,459 patients (466 BIF, 3,993 non‐BIF). Through binary outcome analysis, at 1 year the overall definite/probable stent thrombosis rates were higher in the BIF group (1.84% vs. 0.76%, P = 0.03). However, at 4 years, the difference in cumulative rates of ARC definite/probable stent thrombosis (BIF 2.3% vs. non‐BIF 1.4%, P = 0.13) remained the same as that at 1 year, with no incremental definite/probable stent thrombosis in BIF patients from 2‐4 years. The 4‐year rates of composite cardiac death and MI were 13.5% for BIF vs. 14.1% for non‐BIF (P = 0.78). At 4 years, target lesion failure (19.1% vs. 18.3%, P = 0.66) and ischemia driven‐target lesion revascularization (10.2% vs. 10.1%, P = 0.89) were comparable between the two groups.ConclusionsThis subgroup analysis of BIF lesions in a real world population receiving EES demonstrates continued low rates of clinical outcomes in the BIF subgroup at 4 years with no incremental stent thrombosis increase in BIF patients from 2 to 4 years. © 2015 Wiley Periodicals, Inc.
ChemInform Abstract: Hybridization Gap and Dresselhaus Spin Splitting in EuIr4In2Ge4.
Authors: Calta Nicholas P. , Im Jino , Rodriguez Alexandra P. , Fang Lei , Bugaris Daniel E. , Chasapis Thomas C. , Freeman Arthur J. , Kanatzidis Mercouri G. 
Published: September 2015

AbstractEuIr4In2Ge4 is prepared by flux melting of the elements in the molar ratio of Eu:Ir:Ge:In = 1:1:1:30 (alumina crucible in evacuated silica tubes, 1000 °C, 12 h; cooling to 550 °C over 2 d).
ChemInform Abstract: Black Arsenic—Phosphorus: Layered Anisotropic Infrared Semiconductors with Highly Tunable Compositions and Properties.
Authors: Zhou Chongwu , et al.  
Published: September 2015

AbstractBlack AsxP1‐x (x = 0, 0.25, 0,4) is prepared by vapor transport of a mixture of gray As and red P to which a Sn/SnCl4 mixture is given as mineralizer (evacuated silica tubes, complex heating and cooling schedules) and subsequently exfoliated for optical and electrochemical measurements.
ChemInform Abstract: Ultraviolet Photolysis Studies on XeO4 in Noble‐Gas and F2 Matrices and the Formation and Characterization of a New XeVIII Oxide, (η2‐O2)XeO3.
Authors: Vent‐Schmidt Thomas , Goettel James T. , Schrobilgen Gary J. , Riedel Sebastian 
Published: September 2015

AbstractNa4Xe16O6 (I) and Xe16O4 (II) are prepared by dissolving XeF6 in H2O and adding MgO to precipitate MgF2 which is removed by centrifugation.
ChemInform Abstract: Synthesis and Surface Chemistry of High Quality Wurtzite and Kesterite Cu2ZnSnS4 Nanocrystals Using Tin(II) 2‐Ethylhexanoate as a New Tin Source.
Authors: Gabka Grzegorz , Bujak Piotr , Gryszel Maciej , Ostrowski Andrzej , Malinowska Karolina , Zukowska Grazyna Z. , Agnese Fabio , Pron Adam , Reiss Peter 
Published: September 2015

AbstractA new synthesis of the title nanocrystals is reported, in which solid and difficult to dissolve precursors of tin are replaced by liquid tin(II) 2‐ethylhexanoate.
ChemInform Abstract: Organomagnesium‐Catalyzed Isomerization of Terminal Alkynes to Allenes and Internal Alkynes.
Authors: Rochat Raphael , Yamamoto Koji , Lopez Michael J. , Nagae Haruki , Tsurugi Hayato , Mashima Kazushi 
Published: September 2015

AbstractThe synthesis of a dimeric organomagnesium complex (MGC) is reported.
ChemInform Abstract: A Simple Procedure for the Oxidation of Alcohols Using [Bis(acetoxy)iodo]benzene and a Catalytic Amount of Bromide Ions in Ethyl Acetate.
Authors: Salvo Anna Maria Pia , Campisciano Vincenzo , Beejapur Hazi Ahmad , Giacalone Francesco , Gruttadauria Michelangelo 
Published: September 2015

AbstractThe oxidation of primary and secondary benzylic alcohols to the corresponding aldehydes and ketones proceeds by simple treatment with PhI(OAc)2 and a catalytic amount of bromide ions, Bu4NBr or KBr.
ChemInform Abstract: Iron(III) Catalyzed Halo‐Functionalization of Alkynes.
Authors: Catano Bryant , Lee John , Kim Claudia , Farrell David , Petersen Jeffrey L. , Xing Yalan 
Published: September 2015

AbstractThe FeCl3‐catalyzed reaction of alkynes with NBS or NIS in methanol provides α,α‐dihalodimethyl ketals in excellent yields.
ChemInform Abstract: A General Pd‐Catalyzed α‐ and γ‐Benzylation of Aldehydes for the Formation of Quaternary Centers.
Authors: Franzoni Ivan , Guenee Laure , Mazet Clement 
Published: September 2015

AbstractUsing benzyl methyl carbonates as substrate, a series of α‐branched aldehydes is benzylated.
ChemInform Abstract: Difunctionalization of Alkenes via the Visible‐Light‐Induced Trifluoromethylarylation/1,4‐Aryl Shift/Desulfonylation Cascade Reactions.
Authors: Zheng Lewei , Yang Chao , Xu ZhaoZhong , Gao Fei , Xia Wujiong 
Published: September 2015

Abstractα,β‐Unsaturated imide alkenes are found to undergo a visible light induced trifluoromethylarylation/1,4‐aryl shift/desulfonylation cascade to yield oxindoles.
ChemInform Abstract: Direct Aerobic Carbonylation of C(sp2)—H and C(sp3)—H Bonds Through Ni/Cu Synergistic Catalysis with DMF as the Carbonyl Source.
Authors: Wu Xuesong , Zhao Yan , Ge Haibo 
Published: September 2015

AbstractThe direct carbonylation of C—H bonds of aromatic and aliphatic amides is achieved via nickel/copper synergistic catalysis under atmospheric oxygen with the assistance of a bidendate directing group.
ChemInform Abstract: Tandem Z‐Selective Cross‐Metathesis/Dihydroxylation: Synthesis of anti‐1,2‐Diols.
Authors: Dornan Peter K. , Wickens Zachary K. , Grubbs Robert H. 
Published: September 2015

AbstractRuthenium catalyzes both the metathesis reaction as well as the dihydroxylation reaction upon addition of NaIO4.
ChemInform Abstract: Metal‐Free, Regio‐ and Stereoselective Synthesis of Linear (E)‐Allylic Compounds Using C, N, O, and S Nucleophiles.
Authors: Huang Xiaojun , Fulton Brandon , White Kana , Bugarin Alejandro 
Published: September 2015

AbstractBromination of alkenes (I) give the corresponding dibromides which are further converted into linear (E)‐allylic compounds upon treatment with various nucleophiles.