bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of Different Treatments for Oestrous Induction in Seasonally Anovulatory Mares
Authors: Vizuete G , Diez E , Galisteo J , Agüera E , Aguilera‐Tejero E , Perez‐Marín CC 
Published: November 2012

ContentsThe aim of this study was to evaluate the effects of different treatments for induction and synchronization of oestrus and ovulation in seasonally anovulatory mares. Fifteen mares formed the control group (C), while 26 mares were randomly assigned to three treatment groups. Group T1 (n = 11) were treated with oral altrenogest (0.044 mg/kg; Regumate®) during 11 days. Group T2 (n = 7) was intravaginally treated with 1.38 g of progesterone (CIDR®) for 11 days. In group T3 (n = 8), mares were also treated with CIDR®, but only for 8 days. All mares received PGF2α 1 day after finishing the treatment. Sonographic evaluation of follicles, pre‐ovulatory follicle size and ovulation time was recorded. Progesterone and leptin levels were analysed. Results show that pre‐ovulatory follicles were developed after the treatment in 88.5% of mares. However, the pre‐ovulatory follicle growth was dispersal, and sometimes it was detected when treatment was not finished. While in mares treated with intravaginal device, the follicle was soon detected (1.5 ± 1.2 days and 2.3 ± 2.0 days in T2 and T3 groups, respectively), in T1 group, the pre‐ovulatory follicle was detected slightly later (3.9 ± 1.6 days). The interval from the end of treatment to ovulation did not show significant differences between groups (T1 = 13.1 ± 2.5 days; T2 = 11.0 ± 3.6 days; T3 = 13.8 ± 4.3 days). The pregnancy rate was 47.4%, similar to the rate observed in group C (46.7%; p > 0.05). Initial leptin concentrations were significantly higher in mares, which restart their ovarian activity after treatments, suggesting a role in the reproduction mechanisms in mares. It could be concluded that the used treatments may be effective for oestrous induction in mares during the late phase of the seasonally anovulatory period. Furthermore, they cannot synchronize oestrus, and then, it is necessary to know the reproductive status of mares when these treatments are used for oestrous synchronization.
Limited SP17 expression within tumors diminishes its therapeutic potential
Authors: Gjerstorff M. F. , Ditzel H. J. 
Published: November 2012

AbstractIn this study, we have investigated the expression of the tumor antigen sperm protein 17 (SP17) in a large panel of human cancers and compared it with the expression of two well‐characterized families of tumor antigens, melanoma‐associated antigen‐A (MAGE‐A) and G antigen (GAGE). We found that SP17 was expressed in many cancer types with an overall frequency of 12%. SP17 was most frequently expressed in a different set of cancer types than MAGE‐A and GAGE antigens and rarely overlapped with these proteins. Importantly, SP17 expression was limited to a small number of scattered cancer cells in most positive tumors in contrast to MAGE‐A and GAGE proteins, which were homogenously expressed in large foci. Our results suggest that SP17 may not be an optimal target for cancer vaccines.
Characterization of the major histocompatibility complex class IA alleles in cynomolgus macaques of Vietnamese origin
Authors: Zhang G.‐Q. , Ni Ch. , Ling F. , Qiu W. , Wang H.‐B. , Xiao Y. , Guo X.‐J. , Huang J.‐Y. , Du H.‐L. , Wang J.‐F. , Zhao Sh.‐J. , Zhuo M. , Wang X.‐N. 
Published: November 2012

AbstractCynomolgus macaques (Macaca fascicularis, Mafa) have emerged as an important animal model for infectious disease and transplantation research. Extensive characterization of their major histocompatibility complex (MHC) polymorphism regions therefore becomes urgently required. In this study, we identified 41 MHC class I A nucleotide sequences in 34 unrelated cynomolgus macaques of Vietnamese origin farmed in Southern China, including eight novel Mafa‐A sequences. We found two sequences with perfect identity and six sequences with close similarity to previously defined MHC class I alleles from other populations, especially from Indonesian‐origin macaques. We also found three Vietnamese‐origin cynomolgus macaque MHC class I sequences for which the predicted protein sequences identical throughout their B and F binding pockets to Mamu‐A1*001:01 and Mamu‐A3*13:03, respectively. This is important because Mamu‐A1*001:01 and Mamu‐A3*13:03 are associated with longer survival and lower set‐point viral load in simian immunodeficiency virus (SIV)‐infected rhesus monkeys. These findings have implications for the evolutionary history of Vietnamese‐origin cynomolgus macaque as well as for the use of this model in SIV/SHIV (a virus combining parts of the HIV and SIV genomes) research.
Using HLA loci to inform ancestry and health in Polynesian and Maori populations
Authors: Edinur H. A. , Dunn P. P. J. , Hammond L. , Selwyn C. , Velickovic Z. M. , Lea R. A. , Chambers G. K. 
Published: November 2012

AbstractHuman leukocyte antigens (HLA) are important genetic markers of tissue identity and accurately reflect ancestral history. The work reported in this paper provides a detailed description of HLA polymorphism in Polynesian and Maori individuals in relation to other populations. Our study concerns HLA classes I and II antigens in Polynesian (N = 36) and Maori (N = 114) subjects genotyped at two digit resolution by New Zealand Blood Service Laboratory in Auckland using polymerase chain reaction‐sequence specific oligonucleotide and PCR‐SSP technologies. We have also compared our data with those from other Austronesian‐speaking Mongoloid and Papuan‐speaking Australoid populations in order to test previously published account of the origin of Proto‐Polynesians via gender‐biassed gene flow between these two ancestral populations. We use principal coordinate analysis for this purpose, arguing this approach to be superior to tree‐based methods, because of factors associated with population history and admixture. Our data are in general agreement with earlier work and reflect received wisdom on the dual origin of Proto‐Polynesians. They also show the way in which the genetic make‐up of Polynesian and Maori subjects is changing due to intermarriage with Europeans.
Oral miltefosine for Indian post‐kala‐azar dermal leishmaniasis: a randomised trial
Authors: Sundar Shyam , Sinha Prabat , Jha T. K. , Chakravarty Jaya , Rai Madhukar , Kumar Nawin , Pandey Krishna , Narain M. K. , Verma N. , Das V. N. R. , Das P. , Berman Jonathan , Arana Byron 
Published: November 2012

AbstractObjectiveStandard treatment of Indian post‐kala‐azar dermal leishmaniasis (PKDL) is unsatisfactory because to achieve therapeutic effectiveness, heroic courses of parenteral and toxic agents have to be administered. Our objective was to evaluate oral miltefosine for its potential to provide effective as well as tolerable treatment for this disease.MethodOpen‐label, randomised, parallel‐group multicentric trial. Miltefosine, 100 mg/day to all but one patient, was administered for 12 weeks or 8 weeks, with a target of 18 patients in each treatment group. Key endpoints were tolerance during treatment and efficacy at 12 months of follow‐up.ResultsThe ITT and per‐protocol cure rates after 12 months of follow‐up for patients receiving 12 weeks of therapy were 78% (14 of 18 patients: 95% CI = 61–88%) and 93% (14 of 15 patients: 95% CI = 71–95%), respectively, after 12 months of follow‐up. The ITT and per‐protocol cure rates for patients receiving 8 weeks of therapy were 76% (13 of 17 patients: 95% CI = 53–90%) and 81% (13 of 16 patients: 95% CI = 57–93%), respectively. Gastrointestinal and other adverse events were rare.ConclusionsThis study suggests that oral miltefosine for 2–3 months can be considered a treatment of choice for Indian PKDL.
Severe mental illness at ART initiation is associated with worse retention in care among HIV‐infected Ugandan adults
Authors: Nachega Jean B. , Mutamba Brian , Basangwa David , Nguyen Hoang , Dowdy David W. , Mills Edward J. , Katabira Elly , Nakimuli‐Mpungu Ethel 
Published: November 2012

AbstractObjectiveThe impact of severe mental illness (SMI) on retention in HIV care remains uncertain. We aimed to measure the association between SMI at antiretroviral therapy (ART) initiation and subsequent retention in care in HIV‐infected Ugandan adults.MethodWe conducted cohort study of 773 patients who initiated ART between January 2005 and July 2009 at the Butabika HIV clinic in Kampala, Uganda. SMI was defined as any clinically diagnosed organic brain syndrome, affective disorder or psychotic disorder. We used Kaplan–Meier and Cox proportional hazards analysis to evaluate the association between SMI and retention in care.ResultsThe prevalence of SMI at ART initiation was 23%. Patients with SMI at baseline were similar to those without SMI in terms of age (median [IQR]: 35 [28–40] vs. 35 [30–40], P = 0.03), sex (36% vs. 35% female, P = 0.86) and baseline CD4+ T‐cell count (112 [54–175] vs. 120 [48–187] cells/mm3, P = 0.86). At 12 months after ART initiation, Kaplan–Meier estimates of continuous retention in care were 65% (95% confidence interval, CI: 31–39%) among patients without SMI, vs. 47% (95% CI: 39–55%) among those with SMI (P < 0.001). All‐cause mortality in the two groups was similar: 1.2% vs. 2.0% (P > 0.05). In multivariable analysis, the only baseline variable independently associated with breakage of continuous care was SMI (HR = 1.58, 95% CI: 1.06─2.33).ConclusionsSevere mental illness at ART initiation is associated with worse retention in HIV care in this urban Ugandan referral hospital. As ART is scaled up across sub‐Saharan Africa, greater attention must be paid to the burden of mental illness and its impact on retention in care.
Multidisciplinary Approach to Epizootiology and Pathogenesis of Bat Rabies Viruses in the United States
Authors: Ellison J. A. , Johnson S. R. , Kuzmina N. , Gilbert A. , Carson W. C. , VerCauteren K. C. , Rupprecht C. E. 
Published: November 2012

SummaryZoonotic disease surveillance is typically initiated after an animal pathogen has caused disease in humans. Early detection of potentially high‐risk pathogens within animal hosts may facilitate medical interventions to cope with an emerging disease. To effectively spillover to a novel host, a pathogen may undergo genetic changes resulting in varying transmission potential in the new host and potentially to humans. Rabies virus (RABV) is one model pathogen to consider for studying the dynamics of emerging infectious diseases under both laboratory and field conditions. The evolutionary history of RABV is characterized by regularly documented spillover infections and a series of notable host shifts. Within this context, enhanced field surveillance to improve detection of spillover infections will require validated techniques to non‐invasively differentiate infected from non‐infected individuals. In this study, we evaluate the use of infrared thermography to detect thermal changes associated with experimental RABV infection in big brown bats (Eptesicus fuscus) in a captive colony. Our results indicated that 62% of rabid bats had detectable facial temperature decreases (−4.6°C, SD ± 2.5) compared with pre‐inoculation baseline values. These data suggest potential utility for discriminating rabid bats in natural field settings. In addition, focusing upon RABV circulating in the United States between 2008 and 2011, we confirmed spillover events of bat RABV among carnivores and identified cross‐species transmission events caused by four lineages of RABV associated with insectivorous bats. Additionally, our analysis of RABV glycoprotein sequences identified substitutions in antigenic sites that may affect neutralizing activity associated with monoclonal antibodies proposed for use in human post‐exposure prophylaxis. This study provides a glimpse into RABV pathobiology and spillover dynamics among and between bats and a variety of mesocarnivores.
Genome Sequence of the Aerobic Bacterium Bacillus sp. Strain FJAT-13831
Authors: Liu Guohong , Liu Bo , Lin Naiquan , Tang Weiqi , Tang Jianyang , Lin Yingzhi 
Published: November 2012

ABSTRACT

Bacillus
sp. strain FJAT-13831 was isolated from the no. 1 pit soil of Emperor Qin's Terracotta Warriors in Xi'an City, People's Republic of China. The isolate showed a close relationship to the
Bacillus cereus
group. The draft genome sequence of
Bacillus
sp. FJAT-13831 was 4,425,198 bp in size and consisted of 5,567 genes (protein-coding sequences [CDS]) with an average length of 782 bp and a G+C value of 36.36%.
Draft Genome Sequence of Brevibacillus brevis Strain X23, a Biocontrol Agent against Bacterial Wilt
Authors: Chen Wu , Wang Yunsheng , Li Dingjun , Li Lin , Xiao Qiming , Zhou Qingming 
Published: November 2012

ABSTRACT

Brevibacillus brevis
X23 is an appropriate biocontrol agent against bacterial wilt caused by
Ralstonia solanacearum
. We report herein the draft genome sequence (6,566,879 bp) and a circular plasmid (6,600 bp) of
B. brevis
X23, data which may be helpful for mining the antagonistic activity against
R. solanacearum
.
Draft Genome Sequence for Pseudomonas aeruginosa Strain PAO579, a Mucoid Derivative of PAO381
Authors: Withers T. Ryan , Johnson Shannon L. , Yu Hongwei D. 
Published: November 2012

ABSTRACT

Pseudomonas aeruginosa
is an opportunistic pathogen that establishes a chronic lung infection in individuals afflicted with cystic fibrosis. Here, we announce the draft genome of
P. aeruginosa
strain PAO579, an alginate-overproducing derivative of strain PAO381.
Draft Genome Sequence of Pantoea sp. Strain A4, a Rafflesia-Associated Bacterium That Produces
N
-Acylhomoserine Lactones as Quorum-Sensing Molecules
Authors: Hong Kar-Wai , Gan Han Ming , Low Siew-Moon , Lee Patrick Kok Yuen , Chong Yee-Meng , Yin Wai-Fong , Chan Kok-Gan 
Published: November 2012

ABSTRACT

Pantoea
sp. strain A4 is a Gram-negative bacterium isolated from the
Rafflesia
flower. We present here, for the first time, the genome sequence of
Rafflesia
-associated
Pantoea
sp. strain A4, which exhibited quorum-sensing activity.
Insights from the Genome Sequence of Quorum-Quenching Staphylococcus sp. Strain AL1, Isolated from Traditional Chinese Soy Sauce Brine Fermentation
Authors: Chong Teik-Min , Tung Hun-Jiat , Yin Wai-Fong , Chan Kok-Gan 
Published: November 2012

ABSTRACT

We report the draft genome sequence of
Staphylococcus
sp. strain AL1, which degrades quorum-sensing molecules (namely,
N
-acyl homoserine lactones). To the best of our knowledge, this is the first documentation that reports the whole genome sequence and quorum-quenching activity of
Staphylococcus
sp. strain AL1.
Draft Genome Sequence of the Cyanide-Utilizing Bacterium Pseudomonas fluorescens Strain NCIMB 11764
Authors: Vilo Claudia A. , Benedik Michael J. , Kunz Daniel A. , Dong Qunfeng 
Published: November 2012

ABSTRACT

We report here the 6.97-Mb draft genome sequence of
Pseudomonas fluorescens
strain NCIMB 11764, which is capable of growth on cyanide as the sole nitrogen source. The draft genome sequence allowed the discovery of several genes implicated in enzymatic cyanide turnover and provided additional information contributing to a better understanding of this organism's unique cyanotrophic ability. This is the first sequenced genome of a cyanide-assimilating bacterium.
Genome Sequence of Staphylococcus epidermidis Strain AU12-03, Isolated from an Intravascular Catheter
Authors: Zhang Li , Morrison Mark , Ó Cuív Páraic , Evans Paul , Rickard Claire M. 
Published: November 2012

ABSTRACT

In recent years,
Staphylococcus epidermidis
has become a major nosocomial pathogen and the most common cause of intravascular catheter-related bacteremia, which can increase morbidity and mortality and significantly affect patient recovery. We report a draft genome sequence of
Staphylococcus epidermidis
AU12-03, isolated from an intravascular catheter tip.
Genome Sequence of Janibacter hoylei MTCC8307, Isolated from the Stratospheric Air
Authors: Pawar S. P. , Dhotre D. P. , Shetty S. A. , Chowdhury S. P. , Chaudhari B. L. , Shouche Y. S. 
Published: November 2012

ABSTRACT

Janibacter hoylei
MTCC8307 was isolated from stratospheric air at an altitude of 41.4 km over Hyderabad, India. Here, we present the draft genome of
Janibacter hoylei
MTCC8307, which contains 3,139,099 bp with a G+C content of 72.8 mol%, 2,972 protein-coding genes, and 57 structural RNAs.
Draft Genome Sequence of Cecembia lonarensis Strain LW9
T
, Isolated from Lonar Lake, a Haloalkaline Lake in India
Authors: Shivaji S. , Ara Sreenivas , Singh Aditya , Pinnaka Anil Kumar 
Published: November 2012

ABSTRACT

The draft genome sequence (4.84 Mb) of
Cecembia lonarensis
strain LW9
T
, isolated from a water sample (4.5-m depth) from Lonar Lake, a meteorite-created haloalkaline lake in India, is reported. The enzymes produced by these microorganisms need to be stable under alkaline conditions prevailing in its habitat. Such enzymes would be of immense importance for enzymatic processes operating at high pH.
Genome Sequence of Staphylococcus arlettae Strain CVD059, Isolated from the Blood of a Cardiovascular Disease Patient
Authors: Dinakaran Vasudevan , Shankar Manoharan , Jayashree Sathyanarayanan , Rathinavel Andiappan , Gunasekaran Paramasamy , Rajendhran Jeyaprakash 
Published: November 2012

ABSTRACT

We have isolated a
Staphylococcus arlettae
strain, strain CVD059, from the blood of a rheumatic mitral stenosis patient. Here, we report the genome sequence and potential virulence factors of this clinical isolate. The draft genome of
S. arlettae
CVD059 is 2,565,675 bp long with a G+C content of 33.5%.
Complete Genome Sequence of the Naphthalene-Degrading Bacterium Pseudomonas stutzeri AN10 (CCUG 29243)
Authors: Brunet-Galmés Isabel , Busquets Antonio , Peña Arantxa , Gomila Margarita , Nogales Balbina , García-Valdés Elena , Lalucat Jorge , Bennasar Antonio , Bosch Rafael 
Published: November 2012

ABSTRACT

Pseudomonas stutzeri
AN10 (CCUG 29243) can be considered a model strain for aerobic naphthalene degradation. We report the complete genome sequence of this bacterium. Its 4.71-Mb chromosome provides insights into other biodegradative capabilities of strain AN10 (i.e., benzoate catabolism) and suggests a high number of horizontal gene transfer events.
Genome Sequence of “Candidatus Microthrix parvicella” Bio17-1, a Long-Chain-Fatty-Acid-Accumulating Filamentous Actinobacterium from a Biological Wastewater Treatment Plant
Authors: Muller Emilie E. L. , Pinel Nicolás , Gillece John D. , Schupp James M. , Price Lance B. , Engelthaler David M. , Levantesi Caterina , Tandoi Valter , Luong Khai , Baliga Nitin S. , Korlach Jonas , Keim Paul S. , Wilmes Paul 
Published: November 2012

ABSTRACT

“
Candidatus
Microthrix” bacteria are deeply branching filamentous actinobacteria which occur at the water-air interface of biological wastewater treatment plants, where they are often responsible for foaming and bulking. Here, we report the first draft genome sequence of a strain from this genus: “
Candidatus
Microthrix parvicella” strain Bio17-1.
Draft Genome Sequence of the Novel Enteric Bacterium Galloisinimonas intestini B14
T
KCTC 32180, Isolated from the Gut of a Galloisiana Species (Notoptera: Grylloblattidae) Fossil Insect
Authors: Park Doo-Sang , Bae Kyung Sook , Kim Hyangmi , Shin Ki-Sun , Choi Sang-Haeng , Kim Dae-Soo , Kim Byung-Woo , Oh Hyun-Woo 
Published: November 2012

ABSTRACT

We report the 3.74-Mb genome sequence of
Galloisinimonas intestini
B14
T
, isolated from the gut of one of the world's rarest insect species,
Galloisiana
sp., collected at a Mosan cave, Moonkyung, Gyungsangbook-do, South Korea. Strain B14
T
is a novel genus candidate of the family
Enterobacteriaceae
.
Complete Genome Sequence of Corynebacterium pseudotuberculosis Cp31, Isolated from an Egyptian Buffalo
Authors: Silva Artur , Ramos Rommel Thiago Jucá , Ribeiro Carneiro Adriana , Cybelle Pinto Anne , de Castro Soares Siomar , Rodrigues Santos Anderson , Silva Almeida Sintia , Guimarães Luis Carlos , Figueira Aburjaile Flávia , Vieira Barbosa Eudes Guilherme , Alves Dorella Fernanda , Souza Rocha Flávia , Souza Lopes Thiago , Kawasaki Regiane , Gomes Sá Pablo , da Rocha Coimbra Nilson Antônio , Teixeira Cerdeira Louise , Silvanira Barbosa Maria , Cruz Schneider Maria Paula , Miyoshi Anderson , Selim Salah Abdel Karim , Moawad Mohamed Salah , Azevedo Vasco 
Published: November 2012

ABSTRACT

Corynebacterium pseudotuberculosis
is of major veterinary importance because it affects many animal species, causing economically significant livestock diseases and losses. Therefore, the genomic sequencing of various lines of this organism, isolated from different hosts, will aid in the development of diagnostic methods and new prevention and treatment strategies and improve our knowledge of the biology of this microorganism. In this study, we present the genome of
C. pseudotuberculosis
Cp31, isolated from a buffalo in Egypt.
Complete Genome Sequence of Streptococcus agalactiae GD201008-001, Isolated in China from Tilapia with Meningoencephalitis
Authors: Liu Guangjin , Zhang Wei , Lu Chengping 
Published: November 2012

ABSTRACT

This work describes a whole-genome sequence of
Streptococcus agalactiae
strain GD201008-001, a pathogen causing meningoencephalitis in cultural tilapia in China. The genome sequence provides opportunities to understand the piscine GBS pathogenicity and its genetic basis associated with host tropism.
Complete Genome Sequence of “Candidatus Portiera aleyrodidarum” BT-QVLC, an Obligate Symbiont That Supplies Amino Acids and Carotenoids to Bemisia tabaci
Authors: Santos-Garcia Diego , Farnier Pierre-Antoine , Beitia Francisco , Zchori-Fein Einat , Vavre Fabrice , Mouton Laurence , Moya Andrés , Latorre Amparo , Silva Francisco J. 
Published: November 2012

ABSTRACT

The genome of “
Candidatus
Portiera aleyrodidarum,” the primary endosymbiont of the whitefly
Bemisia tabaci
(Mediterranean species), is reported. It presents a reduced genome (357 kb) encoding the capability to synthetize, or participate in the synthesis of, several amino acids and carotenoids, being the first insect endosymbiont capable of supplying carotenoids.
Draft Genome Sequence of Salimicrobium sp. Strain MJ3, Isolated from Myulchi-Jeot, Korean Fermented Seafood
Authors: Lee Se Hee , Jung Ji Young , Jeon Che Ok 
Published: November 2012

ABSTRACT

Salimicrobium
sp. strain MJ3 was isolated from myulchi-jeot, traditional fermented seafood made from anchovy in South Korea. Here we announce the draft genome sequence of
Salimicrobium
sp. MJ3 with 2,717,782 bp, which consists of 45 contigs (>500 bp in size), and provide a description of their annotation.
Genome Sequence of Stenotrophomonas maltophilia S028, an Isolate Harboring the AmpR-L2 Resistance Module
Authors: Song Shiping , Yuan Xitong , Liu Shiwei , Zhang Ning , Wang Yufei , Ke Yuehua , Xu Jie , Huang Liuyu , Chen Zeliang , Li Yan 
Published: November 2012

ABSTRACT

Multidrug-resistant
Stenotrophomonas maltophilia
has emerged as an important cause of nosocomial infections, which is attributable mainly to the production of diverse β-lactamases by
S. maltophilia
. The L2 β-lactamase mediated by the AmpR-L2 module is the most represented lactamase. Here, we announce the genome sequence of S028, an isolate harboring the AmpR-L2 module.
Genome Sequences of the Primary Endosymbiont “Candidatus Portiera aleyrodidarum” in the Whitefly Bemisia tabaci B and Q Biotypes
Authors: Jiang Zi-Feng , Xia Fangfang , Johnson Kipp W. , Bartom Elizabeth , Tuteja Jigyasa H. , Stevens Rick , Grossman Robert L. , Brumin Marina , White Kevin P. , Ghanim Murad 
Published: November 2012

ABSTRACT

“
Candidatus
Portiera aleyrodidarum” is the obligate primary endosymbiotic bacterium of whiteflies, including the sweet potato whitefly
Bemisia tabaci
, and provides essential nutrients to its host. Here we report two complete genome sequences of this bacterium from the B and Q biotypes of
B. tabaci
.