bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nitrogen as a carrier gas for regime control in focused electron beam induced deposition
Authors: Wachter Stefan , Gavagnin Marco , Wanzenboeck Heinz D. , Shawrav Mostafa M. , Belić Domagoj , Bertagnolli Emmerich 
Published: June 2014

AbstractThis work reports on focused electron beam induced deposition (FEBID) using a custom built gas injection system (GIS) equipped with nitrogen as a gas carrier. We have deposited cobalt from Co2(CO)8, which is usually achieved by a heated GIS. In contrast to a heated GIS, our strategy allows avoiding problems caused by eventual temperature gradients along the GIS. Moreover, the use of the gas carrier enables a high control over process conditions and consequently the properties of the synthesized nanostructures. Chemical composition and growth rate are investigated by energy dispersive X-ray spectroscopy (EDX) and atomic force microscopy (AFM), respectively. We demonstrate that the N2 flux is strongly affecting the deposit growth rate without the need of heating the precursor in order to increase its vapour pressure. Particularly, AFM volume estimation of the deposited structures showed that increasing the nitrogen resulted in an enhanced deposition rate. The wide range of achievable precursor fluxes allowed to clearly distinguish between precursor- and electron-limited regime. With the carrier-based GIS an optimized deposition procedure with regards to the desired deposition regime has been enabled
Translating Knowledge in Rehabilitation: Systematic Review
Authors: Jones C. Allyson , Roop Sanjesh C. , Pohar Sheri L. , Albrecht Lauren , Scott Shannon D. 
Published: June 2014

Background
Clinicians are faced with using the current best evidence to make treatment decisions, yet synthesis of knowledge translation (KT) strategies that influence professional practice behaviors in rehabilitation disciplines remains largely unknown.

Purpose
The purposes of this study were: (1) to examine the state of science for KT strategies used in the rehabilitation professions (physical therapy, occupational therapy, speech-language pathology), (2) to identify the methodological approaches utilized in studies exploring KT strategies, and (3) to report the extent that KT interventions are described.

Data Sources
Eight electronic databases (MEDLINE, CINAHL, ERIC, PASCAL, EMBASE, IPA, Scopus, and CENTRAL) were searched from January 1985 to May 2013 using language (English) restriction.

Study Selection
Eligibility criteria specified articles evaluating interventions or strategies with a primary purpose of translating research or enhancing research uptake into clinical practice.

Data Extraction
Two reviewers independently screened the titles and abstracts, reviewed full-text articles, performed data extraction, and performed quality assessment. The published descriptions of the KT interventions were compared with the Workgroup for Intervention Development and Evaluation Research's (WIDER) Recommendations to Improve the Reporting of the Content of Behaviour Change Interventions.

Data Synthesis
Of a total of 2,793 articles located and titles and abstracts screened, 26 studies were included in the systematic review. Eighteen articles reported interventions that used a multicomponent KT strategy. Education-related components were the predominant KT intervention regardless of whether it was a single or multicomponent intervention. Few studies used reminders or audit and feedback intervention (n=3). Only one study's primary outcome measure was an economic evaluation. No clear delineation of the effect on KT strategies was seen.

Limitations
Diverse studies were included; however, the heterogeneity of the studies was not conducive to pooling the data.

Conclusions
The modest-to-low methodological quality assessed in the studies underscores the gaps in KT strategies used in rehabilitation and highlights the need for rigorously designed studies that are well reported.
Eagle's Syndrome- A case report
Authors: Kumar KV Arun , Mowar Apoorva , Gupta Rajat , Gulati Deepanshu 
Published: June 2014

Eagle’s syndrome represents a group of symptoms that includes recurrent throat pain, globus hystericus, dysphagia, reffered otalgia, and neck pain possibly caused by elongation of the styloid process or ossification of stylohyoid or stylomandibular ligament. We present a case of 21 yrs old female having chief complaint of bilateral preauricular tenderness since one year. Her clinical signs resembled the presentation of Eagle’s Syndrome, which were radiologically confirmed by Orthopantomogram and Computed Tomography. Patient underwent surgical excision of caudal part of the elongated styloid process (styloidectomy). Postoperatively 10 months later, the patient had significant reduction of pain. DOI: http://dx.doi.org/10.3126/ijls.v8i3.10228 International Journal of Life Sciences Vol.8(3): 2014: 1-4
Virtual interactive presence for real-time, long-distance surgical collaboration during complex microsurgical procedures
Authors: Shenai Mahesh B. , Tubbs R. Shane , Guthrie Barton L. , Cohen-Gadol Aaron A. 
Published: June 2014

Object
The shortage of surgeons compels the development of novel technologies that geographically extend the capabilities of individual surgeons and enhance surgical skills. The authors have developed “Virtual Interactive Presence” (VIP), a platform that allows remote participants to simultaneously view each other's visual field, creating a shared field of view for real-time surgical telecollaboration.

Methods
The authors demonstrate the capability of VIP to facilitate long-distance telecollaboration during cadaveric dissection. Virtual Interactive Presence consists of local and remote workstations with integrated video capture devices and video displays. Each workstation mutually connects via commercial teleconferencing devices, allowing worldwide point-to-point communication. Software composites the local and remote video feeds, displaying a hybrid perspective to each participant. For demonstration, local and remote VIP stations were situated in Indianapolis, Indiana, and Birmingham, Alabama, respectively. A suboccipital craniotomy and microsurgical dissection of the pineal region was performed in a cadaveric specimen using VIP. Task and system performance were subjectively evaluated, while additional video analysis was used for objective assessment of delay and resolution.

Results
Participants at both stations were able to visually and verbally interact while identifying anatomical structures, guiding surgical maneuvers, and discussing overall surgical strategy. Video analysis of 3 separate video clips yielded a mean compositing delay of 760 ± 606 msec (when compared with the audio signal). Image resolution was adequate to visualize complex intracranial anatomy and provide interactive guidance.

Conclusions
Virtual Interactive Presence is a feasible paradigm for real-time, long-distance surgical telecollaboration. Delay, resolution, scaling, and registration are parameters that require further optimization, but are within the realm of current technology. The paradigm potentially enables remotely located experts to mentor less experienced personnel located at the surgical site with applications in surgical training programs, remote proctoring for proficiency, and expert support for rural settings and across different counties.
La rénovation par le web ? Dispositifs numériques et évolution du militantisme au PS
Authors: Mabi Clément , Theviot Anaïs 
Published: June 2014

La campagne victorieuse de Barack Obama en 2008 a été largement analysée par de nombreux observateurs en quête d’éléments transposables dans leur contexte national. Sous l’impulsion des trois « Bostoniens » ayant participé à la campagne démocrate, le Parti socialiste a mis en place un système de porte-à-porte coordonné par le site web toushollande.fr. Ce portail avait vocation à mobiliser les « militants rénovés » et des sympathisants. Nous souhaitons étudier comment le site toushollande.fr « traduit » dans son design cette volonté de décloisonnement de l’activité militante et donne une forme matérielle aux discours sur la rénovation du PS.
Offe, la démocratie dialogique et la lutte des classes : une critique participationniste du mouvement ouvrier
Authors: Yon Karel 
Published: June 2014

L’article propose une introduction critique à l’essai de Claus Offe et Helmuth Wiesenthal, « Deux logiques d’action collective ». Alors que Claus Offe est généralement reconnu comme un des principaux théoriciens des « nouveaux mouvements sociaux », ce texte dont il est le principal auteur donne accès à ses analyses sur le « vieux » mouvement ouvrier. L’article a souvent donné lieu à des interprétations le renvoyant du côté de la vulgate marxiste. Or une telle lecture ne rend pas justice à ce qui correspond plutôt au moment particulier où Claus Offe articule sa théorie naissante des nouveaux mouvements sociaux à la perspective indissociablement théorique et politique du marxisme. Son originalité est en effet de formuler une théorie de l’action syndicale qui fait de la formation dialogique des intérêts un ressort essentiel de l’émancipation des dominés. En resituant le texte dans son contexte théorique et politique, on défend l’idée que son intérêt se cache dans le décalage entre la raideur de son vocabulaire et le mouvement de sa pensée.
Deux logiques d'action collective
Authors: Offe Claus , Wiesenthal Helmuth , Yon Karel 
Published: June 2014

L’article critique la fausse équivalence entre organisations syndicales de salariés et d’employeurs induite par le concept de « groupe d’intérêt », qui dissimule les asymétries de pouvoir entre travail et capital. Il s’intéresse ensuite au rôle des formes politiques dans la construction des intérêts et pointe une contradiction. Alors que les modes d’action et de raisonnement supportés par les institutions de la démocratie libérale favorisent une rationalité monologique, la classe laborieuse, en raison de sa position dominée dans la structure de classe, a besoin de formes d’organisation dialogiques pour faire émerger ses intérêts véritables. La distinction entre modes d’action dialogiques et monologiques conduit à mettre au jour deux niveaux différenciés de la lutte des classes. Le premier, qui s’inscrit dans le cadre des formes politiques existantes, est celui des conflits économiques distributifs. Le second porte sur les formes politiques elles-mêmes.
Effect of True Strain on Processing Maps for Processed Ni-Based Superalloy below γ΄-Transus Temperature
Authors: Yang Guo Bao , Yao Ze Kun , Liu Yan Hui , Nan Yang , Ning Yong Quan 
Published: June 2014

Isothermal compression tests were carried out on GH4133B superalloy at 940–1060°C (below nominal γ΄-transus temperature of 1080°C) and 0.001–1.0s-1. The processing maps were constructed to evaluate the efficiency of power dissipation (η) and recognize the flow instability regimes. Our investigations demonstrate that true strain takes great effect on processing maps' evolution. At 1020°C/1.0s-1, the efficiency valueηundergoes a small decline at low strains, and then increases linearly from 0.26 to 0.58 at high strains. However, the efficiency value remains high constant (η=0.40) with the increased strain under the condition of 980°C/0.001s-1. As a result, hot deformation can be carried out firstly at 980°C/0.001s-1with small strain about 0.35 and then carried out at 1020°C/1.0s-1to get fine homogeneous microstructure. There are two instability regimes respectively located around 940°C/1.0s-1and 1060°C/0.001s-1when the strains are 0.05–0.40. Moreover, there is another instability regime located around 1060°C/1.0s-1when the strains are 0.45–0.69.
Texture Evolution of Commercially Pure Copper during Ultra-Thin Strip Rolling
Authors: Song Meng , Liu Xiang Hua , Tang De Lin 
Published: June 2014

Experimental investigation on rolling texture evolution in commercially pure copper thinned from 5.8mm to 20μm by symmetrical rolling and asymmetrical rolling without annealing were carried out via orientation distribution functions and orientation line analysis. The results show that the rolling texture for the sample with initial rotate cube texture {100}<011>mainly consist of C and B, most crystallites aggregate along the α and β orientations lines. The texture density growth rate increased significantly in rolling process. That may relate to size effect of ultra-thin strip. The rate of dislocation reduction was more than dislocation multiplication due to disappear at grain size, when the thickness of ultra-thin strip decreased to an extremely value.
Modeling the Clinical Phenotype of BTK Inhibition in the Mature Murine Immune System
Authors: Benson Micah J. , Rodriguez Varenka , von Schack David , Keegan Sean , Cook Tim A. , Edmonds Jason , Benoit Stephen , Seth Nilufer , Du Sarah , Messing Dean , Nickerson-Nutter Cheryl L. , Dunussi-Joannopoulos Kyri , Rankin Andrew L. , Ruzek Melanie , Schnute Mark E. , Douhan John 
Published: June 2014

Abstract
Inhibitors of Bruton’s tyrosine kinase (BTK) possess much promise for the treatment of oncologic and autoimmune indications. However, our current knowledge of the role of BTK in immune competence has been gathered in the context of genetic inactivation of btk in both mice and man. Using the novel BTK inhibitor PF-303, we model the clinical phenotype of BTK inhibition by systematically examining the impact of PF-303 on the mature immune system in mice. We implicate BTK in tonic BCR signaling, demonstrate dependence of the T3 B cell subset and IgM surface expression on BTK activity, and find that B1 cells survive and function independently of BTK. Although BTK inhibition does not impact humoral memory survival, Ag-driven clonal expansion of memory B cells and Ab-secreting cell generation are inhibited. These data define the role of BTK in the mature immune system and mechanistically predict the clinical phenotype of chronic BTK inhibition.
Porcine Cathelicidins Efficiently Complex and Deliver Nucleic Acids to Plasmacytoid Dendritic Cells and Can Thereby Mediate Bacteria-Induced IFN-α Responses
Authors: Baumann Arnaud , Démoulins Thomas , Python Sylvie , Summerfield Artur 
Published: June 2014

Abstract
Cathelicidins constitute potent antimicrobial peptides characterized by a high cationic charge that enables strong interactions with nucleic acids. In fact, the only human cathelicidin LL-37 triggers rapid sensing of nucleic acids by plasmacytoid dendritic cells (pDC). Among the porcine cathelicidins, phylogenetic analysis of the C-terminal mature peptide showed that porcine myeloid antimicrobial peptide (PMAP)-36 was the most closely related of the 11 porcine cathelicidins to human LL-37. Despite several investigations evaluating potent antimicrobial functions of porcine cathelicidins, nothing is known about their ability to promote pDC activation. We therefore investigated the capacity of the proline-arginine–rich 39-aa peptide, PMAP-23, PMAP-36, and protegrin-1 to complex with bacterial DNA or synthetic RNA molecules and facilitate pDC activation. We demonstrate that these peptides mediate a rapid and efficient uptake of nucleic acids within minutes, followed by robust IFN-α responses. The highest positively charged cathelicidin, PMAP-36, was found to be the most potent peptide tested for this effect. The peptide–DNA complexes were internalized and also found to associate with the cell membranes of pDC. The amphipathic conformation typical of PMAP-36 was not required for IFN-α induction in pDC. We also demonstrate that PMAP-36 can mediate IFN-α induction in pDC stimulated by Escherichia coli, which alone fail to activate pDC. This response was weaker with a scrambled PMAP-36, relating to its lower antimicrobial activity. Collectively, our data suggest that the antimicrobial and nucleic acid–complexing properties of cathelicidins can mediate pDC activation-promoting adaptive immune responses against microbial infections.
Coordinated Histone H3 Methylation and Acetylation Regulate Physiologic and Pathologic Fas Ligand Gene Expression in Human CD4+ T Cells
Authors: Ghare Smita S. , Joshi-Barve Swati , Moghe Akshata , Patil Madhuvanti , Barker David F. , Gobejishvili Leila , Brock Guy N. , Cave Matthew , McClain Craig J. , Barve Shirish S. 
Published: June 2014

Abstract
Activation-induced Fas ligand (FasL) mRNA expression in CD4+ T cells is mainly controlled at transcriptional initiation. To elucidate the epigenetic mechanisms regulating physiologic and pathologic FasL transcription, TCR stimulation–responsive promoter histone modifications in normal and alcohol-exposed primary human CD4+ T cells were examined. TCR stimulation of normal and alcohol-exposed cells led to discernible changes in promoter histone H3 lysine trimethylation, as documented by an increase in the levels of transcriptionally permissive histone 3 lysine 4 trimethylation and a concomitant decrease in the repressive histone 3 lysine 9 trimethylation. Moreover, acetylation of histone 3 lysine 9 (H3K9), a critical feature of the active promoter state that is opposed by histone 3 lysine 9 trimethylation, was significantly increased and was essentially mediated by the p300-histone acetyltransferase. Notably, the degree of these coordinated histone modifications and subsequent recruitment of transcription factors and RNA polymerase II were significantly enhanced in alcohol-exposed CD4+ T cells and were commensurate with the pathologic increase in the levels of FasL mRNA. The clinical relevance of these findings is further supported by CD4+ T cells obtained from individuals with a history of heavy alcohol consumption, which demonstrate significantly greater p300-dependent H3K9 acetylation and FasL expression. Overall, these data show that, in human CD4+ T cells, TCR stimulation induces a distinct promoter histone profile involving a coordinated cross-talk between histone 3 lysine 4 and H3K9 methylation and acetylation that dictates the transcriptional activation of FasL under physiologic, as well as pathologic, conditions of alcohol exposure.
Superimposed Epitopes Restricted by the Same HLA Molecule Drive Distinct HIV-Specific CD8+ T Cell Repertoires
Authors: Sun Xiaoming , Fujiwara Mamoru , Shi Yi , Kuse Nozomi , Gatanaga Hiroyuki , Appay Victor , Gao George F. , Oka Shinichi , Takiguchi Masafumi 
Published: June 2014

Abstract
Superimposed epitopes, in which a shorter epitope is embedded within a longer one, can be presented by the same HLA class I molecule. CD8+ CTL responses against such epitopes and the contribution of this phenomenon to immune control are poorly characterized. In this study, we examined HLA-A*24:02–restricted CTLs specific for the superimposed HIV Nef epitopes RYPLTFGWCF (RF10) and RYPLTFGW (RW8). Unexpectedly, RF10-specific and RW8-specific CTLs from HIV-1–infected HLA-A*24:02+ individuals had no overlapping Ag reactivity or clonotypic compositions. Single-cell TCR sequence analyses demonstrated that RF10-specific T cells had a more diverse TCR repertoire than did RW8-specific T cells. Furthermore, RF10-specific CTLs presented a higher Ag sensitivity and HIV suppressive capacity compared with RW8-specific CTLs. Crystallographic analyses revealed important structural differences between RF10– and RW8–HLA-A*24:02 complexes as well, with featured and featureless conformations, respectively, providing an explanation for the induction of distinct T cell responses against these epitopes. The present study shows that a single viral sequence containing superimposed epitopes restricted by the same HLA molecule could elicit distinct CD8+ T cell responses, therefore enhancing the control of HIV replication. This study also showed that a featured epitope (e.g., RF10) could drive the induction of T cells with high TCR diversity and affinity.
RETRACTION: Challenges of combined everolimus/endocrine therapy in hormone receptor-positive metastatic breast cancer
Authors: Porta Camillo 
Published: June 2014

To our readers:With deep regrets, we inform our Readers that the article Challenges of combined everolimus/endocrine therapy in hormone receptor-positive metastatic breast cancer (DOI: http://dx.doi.org/10.4081/oncol.2014.236), which has been published Ahead of Print in the first issue of Oncology Reviews (2014), contains verbatim text plagiarized from another paper.1The manuscript must be considered as retracted. On behalf of the Editorial Board of Oncology Reviews, I apologize to the Author of the manuscript whose text was plagiarized by Y. Abubakr and Y. Albushra that this was not picked up in the peer review process. I also apologize to the affected journal for the violation of copyright due to plagiarism. Oncology Reviews is uncompromising in its commitment to scientific integrity. When credible evidence of misconduct is brought to our attention, our commitment to the scientific record and to our readership requires immediate notification. Oncology Reviews is increasingly employing sophisticated software to detect plagiarism. Other journals use similar tools. Authors should be aware that most journals routinely employ plagiarism detection software, and that any plagiarism is likely to be detected.Camillo Porta, Editor-in-Chief Oncology Reviews Reference 1. André F. Enhancing effectiveness of endocrine therapy in hormone receptor-positive advanced breast cancer. Medscape Education Oncology. CME Released: 05/24/2013; Valid for credit through 05/24/2014. http://www.medscape.org/viewarticle/804496
Jump-Landing Mechanics After Anterior Cruciate Ligament Reconstruction: A Landing Error Scoring System Study
Authors: Bell David Robert , Smith Mason D. , Pennuto Anthony P. , Stiffler Mikel R. , Olson Matthew E. 
Published: June 2014

Context:
The Landing Error Scoring System (LESS) is a clinical evaluation of jump-landing mechanics and may provide useful information in assisting with return-to-sport decisions in patients after anterior cruciate ligament reconstruction (ACLR). However, it is currently unknown how patients with ACLR perform on the LESS compared with healthy controls.

Objective:
To determine if the total LESS score differed between individuals with ACLR and healthy controls and to determine the types of errors that differ between groups.

Design:
Cross-sectional study.

Setting:
Research laboratory.

Patients or Other Participants:
A total of 27 individuals with unilateral ACLR (age = 19.8 ± 1.8 years, height = 170 ± 5.5 cm, mass = 68.8 ± 11.9 kg) and 27 controls (age = 20.5 ± 1.7 years, height = 169 ± 8.4 cm, mass = 66.6 ± 9.0 kg) with no history of ACLR.

Intervention(s):
Each participant completed 3 trials of a standardized jump-landing task.

Main Outcome Measure(s):
Each jump landing was assessed for specific postures using standardized LESS criteria by a blinded evaluator. Individual LESS items were summed to create a total LESS score. The dominant limb was assessed in the control group, and the reconstructed limb was assessed in the ACLR group.

Results:
The ACLR group had higher LESS scores compared with controls (ACLR: 6.7 ± 2.1 errors, control: 5.6 ± 1.5 errors, P = .04). Additionally, the ACLR group was more likely to err when landing with lateral trunk flexion (Fisher exact test, P = .002).

Conclusions:
Individuals with ACLR had worse landing mechanics as measured by the LESS. Lateral trunk deviation may be related to quadriceps avoidance in the reconstructed limb or poor trunk neuromuscular control. The LESS is useful for evaluating landing errors in patients with ACLR and may help to identify areas of focus during rehabilitation and before return to sport.
All Irrational Extended Rotation Algebras are AF Algebras
Authors: Elliott George A. , Niu Zhuang 
Published: June 2014

AbstractLet θ ∊ [0, 1] be any irrational number. It is shown that the extended rotation algebra Bθ introduced by the authors in J. Reine Angew. Math. 665(2012), pp. 1–71, is always an AF algebra.