bluuebunny/crossref_metadata_2025_split huggingface dataset:
Les suites judiciaires de la mort d'Abdelkader Bouziane
Authors: Cosse Emmanuelle 
Published: October 2014

Résumé	Dammarie, lieu de mémoire. Celle, cuisante, des non-lieux (affaire Bouziane). Celle, méfiante, de la désinformation, d’où l’enjeu de l’image (collectif POIS). Celle du deuil, familière jusqu’au rituel (Xavier Dem, un enterrement politique). Le 17 décembre 1997, peu après 23 heures, Abdelkader Bouziane (16 ans) part au volant de la Volkswagen Golf blanche de sa mère, de Dammarie-lès-Lys vers Nemours, accompagné de son cousin Djamel Bouchareb (19 ans). Ils sont très vite pris en chasse par la Brigade (...)
Spectral statistics for random Schrödinger operators in the localized regime
Authors: Germinet François , Klopp Frédéric 
Published: October 2014

We study various statistics related to the eigenvalues and eigenfunctions of random Hamiltonians in the localized regime. Consider a random Hamiltonian at an energy E in the localized phase. Assume the density of states function is not too flat near E. Restrict it to some large cube . Consider now I, a small energy interval centered at E that asymptotically contains infintely many eigenvalues when the volume of the cube grows to infinity. We prove that, with probability one in the large volume limit, the eigenvalues of the random Hamiltonian restricted to the cube inside the interval are given by independent identically distributed random variables, up to an error of size an arbitrary power of the volume of the cube. As a consequence, we derive
• uniform Poisson behavior of the locally unfolded eigenvalues,
• a.s. Poisson behavior of the joint distibutions of the unfolded energies and unfolded localization centers in a large range of scales,
• the distribution of the unfolded level spacings, locally and globally,
• the distribution of the unfolded localization centers, locally and globally.
Development of a Master Health Facility List in Nigeria
Authors: Makinde Olusesan Ayodeji , Azeez Aderemi , Bamidele Samson , Oyemakinde Akin , Oyediran Kolawole A , Wura Adebayo , Fapohunda Bolaji , Abioye Abimbola , Mullen Stephanie 
Published: October 2014

Introduction: Routine Health Information Systems (RHIS) are increasingly transitioning to electronic platforms in several developing countries. Establishment of a Master Facility List (MFL) to standardize the allocation of unique identifiers for health facilities can overcome identification issues and support health facility management. The Nigerian Federal Ministry of Health (FMOH) recently developed a MFL, and we present the process and outcome.Methods: The MFL was developed from the ground up, and includes a state code, a local government area (LGA) code, health facility ownership (public or private), the level of care, and an exclusive LGA level health facility serial number, as part of the unique identifier system in Nigeria. To develop the MFL, the LGAs sent the list of all health facilities in their jurisdiction to the state, which in turn collated for all LGAs under them before sending to the FMOH. At the FMOH, a group of RHIS experts verified the list and identifiers for each state.Results: The national MFL consists of 34,423 health facilities uniquely identified. The list has been published and is available for worldwide access; it is currently used for planning and management of health services in Nigeria.Discussion: Unique identifiers are a basic component of any information system. However, poor planning and execution of implementing this key standard can diminish the success of the RHIS.Conclusion: Development and adherence to standards is the hallmark for a national health information infrastructure. Explicit processes and multi-level stakeholder engagement is necessary to ensuring the success of the effort.
Calls to the British Columbia Drug and Poison Information Centre: A summary of differences by health service areas
Authors: McLean Kathleen E , Henderson Sarah B , Kent Debra , Kosatsky Tom 
Published: October 2014

Objectives: Poison control centres provide information on the management of poisoning incidents. The British Columbia (BC) Drug and Poison Information Centre recently implemented an electronic database system for recording case information, making it easier to use case data as a potential source of population-based information on health services usage and health status. This descriptive analysis maps poisoning case rates in BC, highlighting differences in patient age, substance type, medical outcome, and caller location.Methods: There were 50,621 human exposure cases recorded during 2012 and 2013. Postal code or city name was used to assign each case to a Health Service Delivery Area (HSDA). Case rates per 1,000 person-years were calculated, including crude rates, age-standardized rates, age-specific rates, and rates by substance type, medical outcome, and caller location. Results: The lowest case rate was observed in Richmond, a city where many residents do not speak English as a first language. The highest rate was observed in the Northwest region, where the economy is driven by resource extraction. Pharmaceutical exposures were elevated in the sparsely populated northern and eastern areas. Calls from health care facilities were highest in the Northwest region, where there are many remote Aboriginal communities. Conclusions: Case rates were generally highest in the primarily rural northern and eastern areas of the province. Considering these results alongside contextual factors informs further investigation and action: addressing cultural and language barriers to accessing poison centre services, and developing a public health surveillance system for severe poisoning events in rural and remote communities.
The interest cost calculation under IAS 19 when discounting with a yield curve
Authors: Olivieri Gennaro , Fersini Paola 
Published: October 2014

Some concerns have been raised in recent discussions on how to calculate the interest cost when measuring the defined benefit obligation (DBO) using a yield curve. This article presents the application of some noted concepts on the yield curve in reference to IAS 19.The issue we investigate specifically concerns the rate or rates to be used when discounting expected liabilities (DBO calculation) and the resulting interest cost (IC) calculation criteria. We analyze three different approaches that are commonly used in actuarial practice.These different methods do not produce significant effects on the amount of DBO, while they lead to annual IC values (and consequently actuarial gains/losses) that may be significantly different in relation to the performance of the yield curve.In this paper, after having reviewed the basic concepts of using a yield curve to evaluate a liability, these concepts are applied to a tangible example in order to quantify the differences that occur in the use of the three approaches. We then show that only the first approach has the characteristics of a model consistent with the assumptions underlying the construction of the model itself.
Temporal and spatial evolution of an on‐land hurricane observed by seismic data
Authors: Tanimoto Toshiro , Lamontagne Anne 
Published: October 2014

AbstractA dense seismic array can provide new perspectives for a decaying hurricane after its landfall. The case of Hurricane Isaac in 2012 is presented using a seismic array from EarthScope (USArray). The amplitude‐distance plots from the center of the hurricane showed a sharp peak at a distance of 75 km at the time of landfall. This peak decayed and moved outward from the center over the next 1.5 days. The sharp peak can be explained by strong surface pressure fluctuations under the eyewall in which a focused ascending flow is known to exist. We reconstructed the time evolution of surface pressure that explains seismic data. Pressure solutions indicate that the eyewall stayed at 75 km in the first 10 h after the landfall, while the ascending flow weakened significantly. In the following 24 h, the eyewall diffused and moved to distances about 200–300 km, suggesting its collapse during this period.
Heterozygous Polg mutation causes motor dysfunction due to mtDNA deletions
Authors: Fuke Satoshi , Kametani Mizue , Yamada Kazuyuki , Kasahara Takaoki , Kubota‐Sakashita Mie , Kujoth Gregory C. , Prolla Tomas A. , Hitoshi Seiji , Kato Tadafumi 
Published: October 2014

AbstractObjectiveMutations in nuclear‐encoded mitochondrial DNA (mtDNA) polymerase (POLG) are known to cause autosomal dominant chronic progressive external ophthalmoplegia (adCPEO) with accumulation of multiple mtDNA deletions in muscles. However, no animal model with a heterozygous Polg mutation representing mtDNA impairment and symptoms of CPEO has been established. To understand the pathogenic mechanism of CPEO, it is important to determine the age dependency and tissue specificity of mtDNA impairment resulting from a heterozygous mutation in the Polg gene in an animal model.MethodsWe assessed behavioral phenotypes, tissue‐specific accumulation of mtDNA deletions, and its age dependency in heterozygous PolgD257A knock‐in mice carrying a proofreading‐deficient mutation in the Polg.ResultsHeterozygous PolgD257A knock‐in mice exhibited motor dysfunction in a rotarod test. Polg+/D257A mice had significant accumulation of multiple mtDNA deletions, but did not show significant accumulation of point mutations or mtDNA depletion in the brain. While mtDNA deletions increased in an age‐dependent manner regardless of the tissue even in Polg+/+ mice, the age‐dependent accumulation of mtDNA deletions was enhanced in muscles and in the brain of Polg+/D257A mice.InterpretationHeterozygous PolgD257A knock‐in mice showed tissue‐specific, age‐dependent accumulation of multiple mtDNA deletions in muscles and the brain which was likely to result in neuromuscular symptoms. Polg+/D257A mice may be used as an animal model of adCPEO associated with impaired mtDNA maintenance.
A 3‐Pyridyl‐5,15‐Diazaporphyrin Nickel(II) Complex as a Bidentate Metalloligand for Transition Metals
Authors: Yamaji Ayaka , Shin Ji‐Young , Miyake Yoshihiro , Shinokubo Hiroshi 
Published: October 2014

Abstract3‐Pyridyl‐5,15‐diazaporphyrin nickel(II) serves as a bidentate metalloligand for platinum(II), ruthenium(II), and rhenium(I) metal centers. Single‐crystal X‐ray diffraction analysis of these metal complexes unambiguously reveals the presence of a dative bond between the outer metal center and the meso‐nitrogen atom. The UV/Vis absorption spectra of the complexes show substantially red‐shifted bands which are perturbed by outer‐metal coordination. This is due to the contribution of metal‐to‐ligand charge transfer interactions.
Structure of an Ancient Egyptian Tomb Inferred from Ground‐Penetrating Radar Imaging of Deflected Overburden Horizons
Authors: Booth Adam D. , Szpakowska Kasia , Pischikova Elena , Griffin Kenneth 
Published: October 2014

AbstractGeophysical data acquisitions in most archaeological campaigns aim to image the target structure directly. The presence of a target, however, may be inferred from its interaction with surrounding layers, if its relationship with those layers can be characterized sufficiently. In this paper, we show the use of ground‐penetrating radar (GPR) to detect the subsurface continuation of the Ancient Egyptian tomb of the high‐official Karakhamun (Theban Tomb 223) at the South Asasif tomb complex (Luxor, Egypt). Data were acquired using a Sensors & Software pulseEKKO PRO system, equipped with antennas of 500 MHz centre‐frequency, on a silty–sandy sediment surface directly over the target structure. A test vertical radar profile (VRP) suggested that the tomb superstructure was buried too deeply beneath sedimentary overburden to be imaged directly: 500 MHz energy would propagate for only ~2 m before becoming undetectable. Attenuative layers within that overburden were strongly reflective, however, and could be used to provide indirect evidence of any underlying structure. When observed in the GPR grid, these layers showed a discrete zone of deflection, ~0.9 m in amplitude and ~4 m wide, aligned with the long‐axis of the tomb. This deflection was attributed either to a collapsed vestibule beneath the survey site, or sediment settling within an unroofed staircase descending from ground‐ to tomb‐floor‐level; supporting evidence of this was obtained towards the end of the excavation campaign and in the following year. We highlight the value of such indirect imaging methods as a potential means of improving the capabilities of a given geophysical survey system, in this case allowing the GPR to characterize a target at greater depth than would typically be considered practical. © 2014 The Authors. Archaeological Prospection published by John Wiley & Sons Ltd.
Tunicamycin‐induced neutrophil extracellular trap (NET)‐like structures in cultured human myeloid cell lines
Authors: Nakayama Tomofumi , Saitoh Hisato 
Published: October 2014

AbstractThe mechanism of neutrophil extracellular trap cell death (NETosis), a regulated cell death pathway relevant to infection, autoimmunity and sepsis, is not completely known. The reason for this, at least in part, is the lack of an in vitro system that recapitulates the NETosis pathway using established human cell lines. We show that exposure of a human promyelocytic leukemia cell line HL‐60 to the glycosyltransferase inhibitor tunicamycin (TM) resulted in extrusion of decompacted genomic DNAs to extracellular space, morphologically similar to NETs. Immunostaining using antibodies against NET marker proteins and bacterial trapping assay showed biochemical similarities between the TM‐induced extracellular DNA structures and NETs. The NET‐like structures were also generated on exposure of TM to other myeloid cell lines, such as U937 and THP‐1. Thus, our findings provide an experimental setting to induce NET‐like structures using cultured human myeloid cell lines, which may help our understanding of the regulation and function of NETosis.
HGF expression induced by HIF‐1α promote the proliferation and tube formation of endothelial progenitor cells
Authors: Yu Feng , Lin Yuhua , Zhan Tao , Chen Lili , Guo Sufen 
Published: October 2014

AbstractHypoxia‐inducible factor‐1α (HIF‐1α) and hepatocyte growth factor (HGF) play important roles in postnatal neovascularization. However, the interaction of these two pathways is not fully understood. The present study utilized CoCl2 treated‐endothelial progenitor cells (EPCs) (EPCs exposure to CoCl2 are under mimic hypoxia) to examine the expressions of HIF‐1α and HGF and futher to assess whether or not the inhibitor (2‐methoxyestradiol [2ME2]) of HIF‐1α decrease the HGF expression. In addition, to investigate the effects of HGF on the proliferation and tube formation of EPCs under mimic hypoxia, EPCs were transfected with NK4 (HGF antagonist) plasmid and exposed to CoCl2, then the proliferation of these EPCs was assayed by MTS and the tube formation capacity of these EPCs on Matrigel was detected. The analysis indicated that CoCl2 treatment induced HIF‐1α expression of EPCs, and futher promoted HGF expression. While after 2ME2 was used in CoCl2 treated‐EPCs, HGF expression was markedly inhibited compared with non‐pretreated EPCs with 2ME2, which also showed that HGF expression in EPCs was mediated by HIF‐1α. Further, the results showed that after EPCs were transfected with NK4 in spite of being exposed to CoCl2, their proliferation activity and tube formation capacity were weakened, which in turn indicated that HGF could promote the proliferation and the tube formation of EPCs, and this process might be regulated by HIF‐1α.
Phosphorus‐Stabilized Titanium Carbene Complexes: Synthesis, Reactivity and DFT Studies
Authors: Lafage Mathieu , Heuclin Hadrien , Le Goff Xavier‐Frédéric , Saffon‐Merceron Nathalie , Mézailles Nicolas 
Published: October 2014

AbstractThe synthesis of two novel titanium carbene complexes from the bis(thiophosphinoyl)methanediide geminal dianion 1 (SCS2−) is described. Dianion 1 reacts cleanly with 0.5 equivalents of [TiCl4(thf)2] to afford the bis‐carbene complex [(SCS)2Ti] (2) in 86 % yield. The mono‐carbene complex [(SCS)TiCl2(thf)] (3) can also be obtained by using an excess of [TiCl4(thf)2]. The structures of 2 and 3 are confirmed by X‐ray crystallography. A strong nucleophilic reactivity towards various electrophiles (ketones and aldehydes) is observed. The reaction of 3 with N,N′‐dicyclohexylcarbodiimide (DCC) and phenyl isocyanate leads to the formation of two novel diphosphinoketenimines 8 a and 8 b. The bis‐titanium guanidinate complex 9 is trapped as the by‐product of the reaction with DCC. The X‐ray crystal structures of 8 a and 9 are presented. The mechanism of the reaction between complex 3 and DCC is rationalized by DFT studies.
Using N‐Tosylhydrazone as a Double Nucleophile in the Palladium‐Catalyzed Cross‐Coupling Reaction To Synthesize Allylic Sulfones
Authors: Zhou Ping‐Xin , Ye Yu‐Ying , Zhao Lian‐Biao , Hou Jian‐Ye , Kang Xing , Chen Dao‐Qian , Tang Qian , Zhang Jie‐Yu , Huang Qi‐Xing , Zheng Lan , Ma Jun‐Wei , Xu Peng‐Fei , Liang Yong‐Min 
Published: October 2014

AbstractWithout extra addition of sulfinate salt, allylic sulfones were synthesized by palladium‐catalyzed cross‐coupling of aryl iodide with N‐tosylhydrazone. In this transformation, not only the diazo compound but also the sulfinate salt, which were both generated in situ from base‐mediated decomposition of the N‐tosylhydrazone, was used as nucleophilic partner.
Ruthenium‐Catalyzed Tandem‐Isomerization/Asymmetric Transfer Hydrogenation of Allylic Alcohols
Authors: Slagbrand Tove , Lundberg Helena , Adolfsson Hans 
Published: October 2014

AbstractA one‐pot procedure for the direct conversion of racemic allylic alcohols to enantiomerically enriched saturated alcohols is presented. The tandem‐isomerization/asymmetric transfer hydrogenation process is efficiently catalyzed by [{Ru(p‐cymene)Cl2}2] in combination with the α‐amino acid hydroxyamide ligand 1, and performed under mild conditions in a mixture of ethanol and THF. The saturated alcohol products are isolated in good to excellent chemical yields and in enantiomeric excess up to 93 %.
Legislative influences on cancer care
Authors: Chalmers Elizabeth 
Published: October 2014

AbstractDeficit reduction politics was a major force in policymaking in the 1980s and a pervasive fact of life in the development of health policy. The Medicare budget was habitually used to find savings for deficit reduction and reforms, such as how to address the problem of 31 to 37 million uninsured Americans, were postponed. The 101st Congress did produce major physician payment reforms and in the spring of 1990, the Pepper Commission issued its recommendations for access to care and long‐term care. Less sweeping but significant proposals affecting cancer care were considered by Congress. For example, positive actions were taken on anti‐smoking and food labeling proposals. Funding for the National Institutes of Health was increased, and there was a growing awareness of the threat to biomedical research presented by assaults on animal research facilities.
A provider's view of prevention approaches in a prepaid group practice
Authors: McK. Lawrence David 
Published: October 2014

AbstractKaiser Permanente's health care delivery system and its efforts to integrate public health preventive medicine and curative medicine are described. The author advocates an increased focus on prepaid delivery systems like Kaiser Permanente as the best vehicle to achieve the full promise of health screening, health education, and life‐style modification. Because these systems have brought the proper incentives into alignment, prevention and health promotion have become effective tools to achieve cost containment goals. A number of Kaiser Permanente projects are highlighted that demonstrate integration of public health preventive medicine and curative medicine: the Northern California Region's uniform health appraisal examination, which is linked with health education and counseling; the Colorado Region's breast cancer screening program, which is expected to show a higher rate of early breast cancer detection than in the general population; cooperative efforts with two Northern California towns to reduce smoking through a community‐wide project; educational theatre programs aimed at early intervention and education of children before high‐risk behaviors have become established life‐style; and research projects that are possible because of an integrated program. Also, several forces that could endanger integrated systems including cost control practices of employers and insurers, and public policy such as mandating specific benefits, are noted.
CO2 Hydrogenation to Methanol on Supported Au Catalysts under Moderate Reaction Conditions: Support and Particle Size Effects
Authors: Hartadi Yeusy , Widmann Daniel , Behm R. Jürgen 
Published: October 2014

AbstractThe potential of metal oxide supported Au catalysts for the formation of methanol from CO2 and H2 under conditions favorable for decentralized and local conversion, which could be concepts for chemical energy storage, was investigated. Significant differences in the catalytic activity and selectivity of Au/Al2O3, Au/TiO2, AuZnO, and Au/ZrO2 catalysts for methanol formation under moderate reaction conditions at a pressure of 5 bar and temperatures between 220 and 240 °C demonstrate pronounced support effects. A high selectivity (>50 %) for methanol formation was obtained only for Au/ZnO. Furthermore, measurements on Au/ZnO samples with different Au particle sizes reveal distinct Au particle size effects: although the activity increases strongly with the decreasing particle size, the selectivity decreases. The consequences of these findings for the reaction mechanism and for the potential of Au/ZnO catalysts for chemical energy storage and a “green” methanol technology are discussed.
A kind of novel VPF‐based energy‐balanced routing strategy for wireless mesh network
Authors: Zhang De‐gan , Wang Xiang , Song Xiao‐dong , Li Jun , Chen You‐jia 
Published: October 2014

SummaryWireless mesh network (WMN) can sense information and realize end‐network transmission. It consists of numerous wireless sensors, the energy and communication ability of which are limited. A kind of novel VPF‐based energy‐balanced routing strategy for WMN has been presented in this paper. Most of the existing energy‐efficient routing strategy always forwards packets along the minimum energy path to the sink to merely minimize energy consumption, which causes an unbalanced distribution of residual energy among sensor nodes, and eventually results in a network partition. We design the energy‐balanced routing strategy by setting up a mixed virtual potential field in terms of depth and energy by using the physical potential concept. The strategy can force packets to move toward the sink through the dense energy area and protect the nodes, which has relatively low residual energy. By comparing to the other energy‐efficient routing strategy in our designed scenarios, the experimental results show that energy balance and throughput can be improved. Copyright © 2014 John Wiley & Sons, Ltd.