bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effectiveness of multicomponent interventions in primary healthcare settings to promote continuous smoking cessation in adults: a systematic review
Authors: Martín Cantera Carlos , Puigdomènech Elisa , Ballvé Jose Luis , Arias Olga Lucía , Clemente Lourdes , Casas Ramon , Roig Lydia , Pérez-Tortosa Santiago , Díaz-Gete Laura , Granollers Sílvia 
Published: October 2015

ObjectiveThe objective of the present review is to evaluate multicomponent/complex primary care (PC) interventions for their effectiveness in continuous smoking abstinence by adult smokers.DesignA systematic review of randomised and non-randomised controlled trials was undertaken.Eligibility criteria for included studiesSelected studies met the following criteria: evaluated effects of a multicomponent/complex intervention (with 2 or more intervention components) in achieving at least 6-month abstinence in adult smokers who visited a PC, biochemical confirmation of abstinence, intention-to-treat analysis and results published in English/Spanish.MethodsWe followed PRISMA statement to report the review. We searched the following data sources: MEDLINE, Web of Science, Scopus (from inception to February 2014), 3 key journals and a tobacco research bulletin. The Scottish Intercollegiate Guidelines Network checklists were used to evaluate methodological quality. Data selection, evaluation and extraction were done independently, using a paired review approach. Owing to the heterogeneity of interventions in the studies included, a meta-analysis was not conducted.ResultsOf 1147 references identified, 9 studies were selected (10 204 participants, up to 48 months of follow-up, acceptable methodological quality). Methodologies used were mainly individual or group sessions, telephone conversations, brochures or quit-smoking kits, medications and economic incentives for doctors and no-cost medications for smokers. Complex interventions achieved long-term continuous abstinence ranging from 7% to 40%. Behavioural interventions were effective and had a dose–response effect. Both nicotine replacement and bupropion therapy were safe and effective, with no observed differences.ConclusionsMulticomponent/complex interventions in PC are effective and safe, appearing to achieve greater long-term continuous smoking cessation than usual care and counselling alone. Selected studies were heterogeneous and some had significant losses to follow-up. Our results show that smoking interventions should include more than one component and a strong follow-up of the patient to maximise results.
Effect of annealing temperature on structural and magnetic properties of strontium hexaferrite nanoparticles synthesized by sol–gel auto-combustion method
Authors: Roohani Ebrahim , Arabi Hadi , Sarhaddi Reza , Sudkhah Saeedeh , Shabani Ameneh 
Published: October 2015

In this paper, strontium hexaferrite nanoparticles were synthesized by the sol–gel auto-combustion method. Effect of annealing temperature on crystal structure, morphology and magnetic properties of nanoparticles was investigated by X-ray diffraction (XRD), Fourier transform infrared (FT-IR), transmission electron microscopy (TEM) and vibrating sample magnetometer (VSM). Also, the thermal decomposition of as-synthesized powdered samples has been studied by thermogravimetric analysis (TGA). The XRD patterns confirmed the formation of single phase M-type hexagonal crystal structure for powders annealed above 950[Formula: see text]C, whereas the presence of hematite ([Formula: see text]-Fe2O3) as secondary phase was also observed for sample annealed at 900[Formula: see text]C. Furthermore, the crystallinity along with the crystallite size were augmented with annealing temperature. Comparison of the FT-IR spectra of the samples before and after annealing treatment showed the existence of metal–oxygen stretching modes after annealing. The thermogravimetric analysis confirmed the thermal decomposition of as-burnt powders happened in three-stage degradation process. The TEM images showed the nanoparticles like hexagonal-shaped platelets as the size of nanoparticles increases by increasing the annealing temperature. With increasing annealing temperature, the magnetic saturation and the coercivity were increased to the maximum value of 74.26 emu/g and 5.67 kOe for sample annealed at 1000[Formula: see text]C and then decreased.
Mediação da Informação em Turismo: um estudo introdutório
Authors: Medaglia Juliana , Ortega Cristina Dotta 
Published: October 2015

<p>O turismo é uma atividade presente na sociedade contemporânea e que vem, de um lado, sendo popularizado como atividade de lazer acessível a uma parcela considerável da população mundial, e, de outro, gerando interesse acadêmico como objeto de estudo. Nesses contextos, o turismo possui vinculo marcante com a informação, da qual depende e com a qual interage constantemente. Ponderando essa relação, apresenta-se aqui uma reflexão acerca dessas áreas, considerando a utilização das metodologias da Ciência da Informação para a atividade turística, enfatizando os desafios e possibilidades da mediação no contexto informacional turístico. Para tanto, metodologicamente, lançou-se mão de pesquisa bibliográfica, analisando fontes secundárias acerca dos temas. Os principais resultados das relações propostas apontam para semelhanças entre as áreas de Ciência da Informação e Turismo especialmente no que diz respeito ao caráter aplicado dos estudos dessas áreas e seu surgimento e desenvolvimento marcados pela influência interdisciplinar. Além disso, percebe-se que ante à dependência que o turismo possui em relação à informação, seja por parte dos turistas que a usam para tomar a decisão de viajar, seja por parte dos estudiosos do tema, esses usuários têm acesso a uma grande quantidade de informação, de onde se deriva a importância da mediação no processo de construção do conhecimento turístico, como um elemento chave da comunicação.</p>
Experiência pedagógica educomunicativa: o cinema nas Licenciaturas
Authors: Almeida Maria do Carmo Souza de 
Published: October 2015

<p> </p><p>Resumo: O objetivo deste artigo é relatar uma experiência pedagógica com narrativas fílmicas em duas Licenciaturas da Universidade de Taubaté. A prática ocorreu no horário destinado às Atividades Acadêmico-Científico-Culturais (AACC). Foram exibidos principalmente filmes que fogem aos padrões tradicionaisque os sujeitos participantes da pesquisa conhecem.Depois das exibições, acontecia uma discussão entre professora pesquisadora e alunos sobre aspectos considerados significativos por eles. Por meio de relatos escritos e de gravações, procurou-se identificar como os estudantes atribuíam sentidos aos filmes vistos. Observou-se que uma prática educomunicativa com narrativas fílmicas na formação docente das Licenciaturas em questão pode contribuir para ampliar o capital cultural dos discentes, logo, para sua construção identitária pessoal e profissional.</p>
Entre palavras e imagens. Onde fica mesmo o índio na fundação do Brasil? Uma discussão a partir dos filmes: Palavra e Utopia (2000) e Anchieta, José do Brasil (1977).
Authors: Magno Maria Ignes Carlos 
Published: October 2015

<p>A proposta dessa resenha é discutir a partir dos filmes: <em>Palavra e Utopia, </em>do cineasta Manoel de Oliveira e <em>Anchieta, José do Brasil</em>, de Paulo César Saraceni, as complexas relações entre os colonizadores e os indígenas do Brasil. Tendo a <em>palavra</em> como o elemento central das reflexões, pensei em dois filmes que mostram através das <em>imagens</em> a força da <em>palavra</em> e a ambiguidade dos sentimentos dos colonizadores em relação ao Brasil e aos aborígines. A proposta aqui não é abordar os textos e os filmes sob a ótica do afeto, mas da ambiguidade contidas nos afetos e nos discursos dos padres José de Anchieta e Antonio Vieira. </p>
Therapeutic Inhibition of miR-33 Promotes Fatty Acid Oxidation but Does Not Ameliorate Metabolic Dysfunction in Diet-Induced Obesity
Authors: Karunakaran Denuja , Richards Laura , Geoffrion Michele , Barrette Danyk , Gotfrit Ryan J. , Harper Mary-Ellen , Rayner Katey J. 
Published: October 2015

Objective—
miR-33 has emerged as an important regulator of lipid homeostasis. Inhibition of miR-33 has been demonstrated as protective against atherosclerosis; however, recent studies in mice suggest that miR-33 inhibition may have adverse effects on lipid and insulin metabolism. Given the therapeutic interest in miR-33 inhibitors for treating atherosclerosis, we sought to test whether pharmacologically inhibiting miR-33 at atheroprotective doses affected metabolic parameters in a mouse model of diet-induced obesity.

Approach and Results—

High-fat diet (HFD) feeding in conjunction with treatment of male mice with 10 mg/kg control anti-miR or anti-miR33 inhibitors for 20 weeks promoted equivalent weight gain in all groups. miR-33 inhibitors increased plasma total cholesterol and decreased serum triglycerides compared with control anti-miR, but not compared with PBS-treated mice. Metrics of insulin resistance were not altered in anti-miR33–treated mice compared with controls; however, respiratory exchange ratio was decreased in anti-miR33–treated mice. Hepatic expression of miR-33 targets
Abca1
and
Hadhb
were derepressed on miR-33 inhibition. In contrast, protein levels of putative miR-33 target gene SREBP-1 or its downstream targets genes
Fasn
and
Acc
were not altered in anti-miR33–treated mice, and hepatic lipid accumulation did not differ between groups. In the adipose tissue, anti-miR33 treatment increased
Ampk
gene expression and markers of M2 macrophage polarization.

Conclusions—
We demonstrate in a mouse model of diet-induced obesity that therapeutic silencing of miR-33 may promote whole-body oxidative metabolism but does not affect metabolic dysregulation. This suggests that pharmacological inhibition of miR-33 at doses known to reduce atherosclerosis may be a safe future therapeutic.
Nanohystricidae n. fam., an unusual, plesiomorphic enarthronote mite family endemic to New Zealand (Acari, Oribatida)
Authors: NORTON ROY A. , FUANGARWORN MARUT 
Published: October 2015

Nanohystrix hammerae n. gen., n. sp.—proposed on the basis of numerous adults and a few juveniles—is a new oribatid mite of the infraorder Enarthronota that appears to be phylogenetically relictual and endemic to northern New Zealand, in habitats ranging from native shrublands to native and semi-native forests. With an adult body length of 1–1.2 mm, the species is the largest known enarthronote mite outside Lohmanniidae, and it has an unusual combination of plesiomorphic and apomorphic traits. Plesiomorphies include: a well-formed median (naso) eye and pigmented lateral eyes; a bothridial seta with a simple, straight base; a vertically-oriented gnathosoma; a peranal segment; adanal sclerites partially incorporated in notogaster (uncertain polarity); three genu I solenidia and a famulus on tarsus II. Autapomorphies include: five pairs of pale cuticular disks on the notogaster, with unknown function; six pairs of long, erectile notogastral setae, including pair h2 incorporated in the second transverse scissure along with the f-row, and pair h1 in a third scissure; chelicerae that are unusually broad, creating a flat-faced appearance; legs I that are inferred to have an unusually wide range of motion. Further, it is the only enarthronote species known to have an elongated ovipositor, and one of few to have glassy, luminous notogastral setae. The gastronotum of juveniles lacks transverse scissures, but has isolated sclerites supporting setae, including erectile setae. The large character gaps between N. hammerae and other enarthronote taxa justifies proposal of a monotypic new family—Nanohystricidae n. fam.—which is tentatively grouped with several other relictual families in the paraphyletic Heterochthonioidea. Small muscles appear to be involved in the operation of all erectile setae, but seem to be only depressors, with erection effected by hysterosomal distension. Based on gut contents, its food is primarily fungal hyphae and spores, though ingestion of small arthropods also occurs (perhaps by necrophagy). Collections were made by Berlese-funnel samples of litter, by sweeping low vegetation, and (mainly) by pitfall traps; the latter two suggest that adults are surface-active. Tritonymphs were collected by pitfall traps, but earlier juveniles were collected only by Berlese-funnels. Adults are frequently infected with a eugregarine parasite, which can entirely fill the digestive caeca; immature trophozoites were also seen in tritonymphs. Adults also can serve as hosts for dispersal of secondary capilliconidia of the fungal genus Basidiobolus.
Feature-Based Diagnostic Evaluation of Global NWP Forecasts
Authors: Mittermaier Marion , North Rachel , Semple Adrian , Bullock Randy 
Published: October 2015

AbstractWith the resolution of global numerical weather prediction (NWP) models now typically between 10 and 20 km, forecasts are able to capture the evolution of synoptic features that are important drivers for significant surface weather. The position, timing, and intensity of jet cores, surface highs and lows, and changes in the behavior of these forecast features is explored using the Method for Object-based Diagnostic Evaluation (MODE) at the global scale. Previously this was only possible with a more subjective approach. The spatial aspects of the forecast features (objects) and their intensity can be assessed separately. The evolution of paired forecast–analysis object attributes such as location and orientation differences, as well as area ratios, can be considered. The differences in the paired object attribute distributions from various model configurations were evaluated using the k-sample Anderson–Darling (AD) test. Increases or decreases in hits, false alarms (forecast-not-observed), and misses (observed-not-forecast) features were also assessed. It was found that when focusing purely on the forecast features of interest, differences in seasonal spatial extent biases emerged, intensity biases varied as a function of analysis time, and changes in the attribute distributions could be detected but were largely insignificant, primarily due to sample size. As has been shown for kilometer-scale NWP, results from spatial verification methods are more in line with subjective assessment. This type of objective assessment provides a new dimension to the traditional assessment of global NWP, and provides output that is closer to the way in which forecasts are used.
Policy coordination and integration, trust, management and performance in public health-related policy networks: a survey
Authors: Peters Dorothee T.J.M. , Klijn Erik Hans , Stronks Karien , Harting Janneke 
Published: October 2015

Intersectoral policy networks may be effective in dealing with complex public health problems. Their performance is assumed to depend on network management and trust, as well as on integrated public health policy (i.e. policy coordination and integration). We studied the role of network management and trust in the realization of integrated public health policy and network performance, as well as the relation between integrated public health policy and network performance. In 34 Dutch local policy networks, we measured the perceptions of 278 actors through a Web-based survey and used regression analyses to assess the relations between policy variables. Management and trust were positively related to perceived integrated public health policy and network performance, while integrated public health policy was also positively related to perceived network performance. In public health, the performance of intersectoral policy networks may be improved by adequate network management, the creation of trust and policy coordination and integration. Future research could further explore the role of specific characteristics of the network manager, like the manager’s background, relation to the other actors and leadership style. Points for practitioners Regarding inter-sectoral policy networks in public health: first, when aiming for the realization of policy coordination and integration, the employment of network management strategies and the creation of trust are of importance for the network manager; and, second, when also aiming for the realization of network performance, the creation of policy coordination and integration is of additional importance for the network manager.
Sensitivity, Specificity, and Posttest Probability of Parotid Fine‐Needle Aspiration
Authors: Liu C. Carrie , Jethwa Ashok R. , Khariwala Samir S. , Johnson Jonas , Shin Jennifer J. 
Published: October 2015

Objectives(1) To analyze the sensitivity and specificity of fine‐needle aspiration (FNA) in distinguishing benign from malignant parotid disease. (2) To determine the anticipated posttest probability of malignancy and probability of nondiagnostic and indeterminate cytology with parotid FNA.Data SourcesIndependently corroborated computerized searches of PubMed, Embase, and Cochrane Central Register were performed. These were supplemented with manual searches and input from content experts.Review MethodsInclusion/exclusion criteria specified diagnosis of parotid mass, intervention with both FNA and surgical excision, and enumeration of both cytologic and surgical histopathologic results. The primary outcomes were sensitivity, specificity, and posttest probability of malignancy. Heterogeneity was evaluated with the I2 statistic. Meta‐analysis was performed via a 2‐level mixed logistic regression model. Bayesian nomograms were plotted via pooled likelihood ratios.ResultsThe systematic review yielded 70 criterion‐meeting studies, 63 of which contained data that allowed for computation of numerical outcomes (n = 5647 patients; level 2a) and consideration of meta‐analysis. Subgroup analyses were performed in studies that were prospective, involved consecutive patients, described the FNA technique utilized, and used ultrasound guidance. The I2 point estimate was >70% for all analyses, except within prospectively obtained and ultrasound‐guided results. Among the prospective subgroup, the pooled analysis demonstrated a sensitivity of 0.882 (95% confidence interval [95% CI], 0.509‐0.982) and a specificity of 0.995 (95% CI, 0.960‐0.999). The probabilities of nondiagnostic and indeterminate cytology were 0.053 (95% CI, 0.030‐0.075) and 0.147 (95% CI, 0.106‐0.188), respectively.ConclusionFNA has moderate sensitivity and high specificity in differentiating malignant from benign parotid lesions. Considerable heterogeneity is present among studies.
Effects of Whole Body Vibration Exercise associated with Quadriceps Resistance Exercise on functioning and quality of life in patients with knee osteoarthritis: a randomized controlled trial
Authors: Wang Pu , Yang Lin , Liu Chuan , Wei Xiaofei , Yang Xiaotian , Zhou Yujing , Jiang Hua , Lei Zhongjie , Reinhardt Jan D. , He Chengqi 
Published: October 2015

Objective: To determine effects of Whole Body Vibration Exercise (WBVE) associated with quadriceps resistance exercises (QRE) versus QRE only on pain, physical function, biomarkers in serum and urine, activities of daily living (ADL), and quality of life in patients with knee osteoarthitis (OA). Design: Randomized-controlled trial . Setting: Rehabilitation medicine outpatient department of West China Hospital, Chengdu, Sichuan, People’s Republic of China. Subjects: Forty-nine patients were assigned to WBVE+QRE and 50 to QRE . Main outcome measures: Primary outcomes included pain assessed with visual analogue scale (VAS), Timed up & go test (TUG), 6-min walk distance test (6MWD), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Secondary outcomes comprised range of motion, muscular strength, serum COMP and urinary CTX-II, Lequesne Index (LI), and SF-36. All outcomes were analyzed with mixed effects regression. Results: Compared with QRE, WBVE+QRE showed signiﬁcantly greater improvement in VAS at 4weeks ( p=0.03), in VAS ( p<0.01), 6MWD ( p=0.01), WOMAC pain ( p=0.01), and WOMAC physical function ( p=0.02) at 16 weeks, and in all primary outcomes at 24 weeks (all p<0.01). Conclusion: Over a six months period, WBVE in combination with QRE was superior to QRE in most outcomes.
Bcl-2 and Fas expression in peripheral blood leukocytes of patients with alcoholic and autoimmune liver disorders
Authors: Zwolak A , Surdacka A , Daniluk J 
Published: October 2015

Background: This article is devoted to the inquiry of three diseases of the liver: alcoholic liver disease (ALD), primary biliary cirrhosis (PBC), and autoimmune hepatitis (AIH). The aim of the study was to assess the changes in populations of circulating lymphocytes expressing antiapoptotic bcl-2 molecule and proapoptotic Fas (cluster of differentiation 95(CD95)) receptor in patients with ALD, AIH, and PBC. Materials and Methods: The study population consisted of 110 patients with ALD ( n = 50), PBC ( n = 30), and AIH ( n = 30) and age-matched healthy volunteers ( n = 25). Peripheral blood lymphocytes were isolated, stained with monoclonal antibodies against CD4, CD8, and CD19 antigen; intracellular bcl-2; and surface Fas receptor (CD95) antigens, and estimated using the flow cytometric method. Results: Bcl-2 expression was the highest in CD4+ and CD19+ T lymphocytes in ALD; however, only the differences in median/mean fluorescence intensity values of CD4+bcl-2+ lymphocytes between ALD and PBC group and CD19+bcl-2+ between ALD and PBC groups were statistically significant, indicating the different role of B cells in pathology of ALD and PBC. In contrast to that, statistically significant higher percentage of CD4+, CD8+, and CD19+ bearing Fas receptor in all groups of patients with liver diseases in comparison with the control subjects were estimated. The highest expression of Fas in CD4+ lymphocytes in ALD and in CD8+ cells of PBC and AIH groups were detected. Conclusion: Low expression of bcl-2 molecule and high expression of Fas in peripheral blood lymphocytes indicate significant dysregulation of apoptotic mechanisms not only in the liver but also in peripheral blood lymphocytes in all examined groups, especially in ALD group.