bluuebunny/crossref_metadata_2025_split huggingface dataset:
SISTEM INFORMASI MANAJEMEN SEKOLAH BERBASIS INFORMATION COMMUNICATION TECHNOLOGY (ICT) DALAM PENINGKATKAN MUTU PENDIDIKAN SISWA DI LINGKUNGAN PESANTREN
Authors: PRAMUNGKAS PATREA REOLA 
Published: August 2024

This article analyzes the possible implementation of School Based Management Information System in terms of Information Communication Technologies (ICT) in advancing the quality of educational service for students in islamic boardingschool. This article figures out that pesantren has implemented ICT based Management Information System in order to archieve program of teaching-learning process, to use learning facilities, curriculum, and to increase the teacher professionalism. The planning is implemented by making vision, mission, goals, and strategies in such a way of well structured management. However, there are some obstacles with which pesantren agencies have to deal in implementing this system, such as: limited access of internet and lack of teacher’s experience in using technology of information. Keywords: Management Information System, Information Communication Technology, Quality of Pesantren
Formula of Romance in the Redeeming Love (2022) Movie
Authors: Jusrianti Jusrianti , Rasiah Rasiah , Arman Arman 
Published: August 2024

This research aims to analyze the formula of romance in the Redeeming Love (2022) movie. The focus of the problem is the convention and invention formula of romance in the Redeeming Love (2022) movie. The theory of Formula from John G. Cawelti analyzes the problem. This research method is descriptive qualitative. From the analysis results, the researcher found convention and invention in the movie. In terms of convention, this movie still maintains the romance formula, such as (1) The romance plot still consists of their first meeting, the man winning the woman, the conflict, and the happy ending. (2) The figure of romance still the presence of the hero and heroine namely Michael and Angel. (3) The setting of romance consists of a place or setting on a hill, a time setting such as in the morning, afternoon, and evening, and an atmosphere setting such as happy, regretful, angry, tense, sad, worried, and afraid. As for the invention of new romance elements found in the movie, such as (1) Romance narrative structure using a mixed pattern of Cinderella pattern, Pamela pattern, and contemporary pattern, (2) The character of romance, such as the hero is described as an ordinary, popular and beautiful heroine, and heroine who has a stubborn nature, (3) The plot of romance, such as Hero gives up on heroine.
Pengembangan Aplikasi Pantau Pembelajaran Berbasis Android Studi Kasus SD Plus Sunan Ampel Kediri
Authors: Widyastuti Ratna , Kurniawan Iqbra , Salam Alaik Annas 
Published: August 2024

Pendidik merupakan pekerjaan yang memiliki tanggung jawab kemanusiaan yang besar, khususnya berkaitan dengen keberhasilan pembelajaran generasi penerus bangsa. Berkembangnya penyelenggaraan pendidikan memunculkan sekolah-sekolah yang menginplementasi kurikulum plus. Kurikulum tersebut memadukan antara kurikulum adaptif dan kurikulum agama. Permasalahannya pendidik pada sekolah yang memiliki kurikulum plus harus memastikan kegiatan belajar tetap berjalan, meskipun peserta didik berada di rumah. Solusinya, pendidik dituntut mendesain media sebagai inovasi dengan memanfaatkan teknologi informasi untuk memantau kegiatan pembelajaran yang berlangsung di rumah. Pendidik dapat bekerjasama dengan orang tua melakukan kegiatan pemantauan. Berdasarkan masalah tersebut, penelitian ini bertujuan mengembangkan aplikasi pantau pembelajaran berbasis android. Metode Pengembangan sistem pada penelitian ini menggunakan metode pengembangan waterfall. Waterfall method, terdiri dari System Analysis, System design, Coding, Testing, Implementasi.Aplikasi pantau pembelajaran dirancang menggunakan bahasa pemrograman kotlin dan mysql sebagai database untuk menyimpan data. Hasil pengujian menggunakan black box testing menunjukkan semua fungsi pada aplikasi pantau pembelajaran berjalan sesuai rancangan, yaitu staf TU pada aplikasi ini dapat menambah data siswa, menambah data wali siswa, menambah data guru dan melihat data history aktivitas; guru kelas berhasil melihat laporan dari wali siswa dan mengirim catatan tugas kepada wali siswa; dan wali siswa dapat melaporkan kegiatan aktivitas siswa setiap hari (belajar, mengaji, sholat), menerima catatan notifikasi yang diberikan oleh guru kelas dan catatan orang tua.
Biochar as a novel carrier affects Brassica napus L. growth, soil phosphorus fractions, and its uptake
Authors: Ibrahim Muhammad , Rubab Mehwish , Nasr Talha , Hassan Ayesha , Ayaz Shamsa 
Published: August 2024

Biochar increases soil fertility by enhancing nutrients retention in amended soil. In addition, biochar increases phosphorus availability in soil by reducing leaching process. The performance of biochar serving as an inoculum carrier depends on physicochemical properties (pH, porosity and, surface area) that impact the establishment of plant growth-promoting bacteria in amended soil. Biochar is largely used as a soil amendment for soil remediation and plants growth. However, little work has been conducted considering biochar suitability when applied as a carrier, which has resulted in inconsistent outcomes. In the present study, six biochar carriers including rice straw biochar (RSB), rice husk biochar (RHB), soybean straw biochar (SSB), peanut shells biochar (PNB), corn cobs biochar (CCB), and wood biochar (WB) were prepared and inoculated with liquid suspension of a phosphate solubilizing bacteria (PSB) identified as Bacillus megaterium KU647234 in a pot experiment. The data revealed that rape (Brassica napus L.) growth and biomass were significantly (P≤ 0.05) improved by up to 304% with amendments of carriers, particularly soybean straw (SSB). P bioaccumulation in roots, stems, and leaves increased significantly (P≤ 0.05) by up to 74%, 111%, and 75% respectively. In addition, RSB, SSB, RHB, PNB, WB, and CCB amendments Plate count assay data revealed that six carriers sustained the Bacillus megateriumabundance to varying degrees. The SSB carrier was identified as the best carrier that sustained higher rape biomass, and P bioaccumulation compared with other carriers
Evaluation and modeling of diaphragm displacement using ultrasound imaging for wearable respiratory assistive robot
Authors: Zhang Yan , Li Danye , Zhang Fengyao , Wang Zongyu , Xue Lei , Nan Xiaolu , Li Nianming , Tan Xilai , Guo Weidong , Zhang Yuru , Zhao Hongmei , Ge Qinggang , Wang Dangxiao 
Published: August 2024

IntroductionAssessing the influence of respiratory assistive devices on the diaphragm mobility is essential for advancing patient care and improving treatment outcomes. Existing respiratory assistive robots have not yet effectively assessed their impact on diaphragm mobility. In this study, we introduce for the first time a non-invasive, real-time clinically feasible ultrasound method to evaluate the impact of soft wearable robots on diaphragm displacement.MethodsWe measured and compared diaphragm displacement and lung volume in eight participants during both spontaneous and robotic-assisted respiration. Building on these measurements, we proposed a human-robot coupled two-compartment respiratory mechanics model that elucidates the underlying mechanism by which our extracorporeal wearable robots augments respiration. Specifically, the soft robot applies external compression to the abdominal wall muscles, inducing their inward movement, which consequently pushes the diaphragm upward and enhances respiratory function. Finally, we investigated the level and shape of various robotic assistive forces on diaphragm motion.ResultsThis robotic intervention leads to a significant increase in average diaphragm displacement by 1.95 times and in lung volume by 2.14 times compared to spontaneous respiration. Furthermore, the accuracy of the proposed respiratory mechanics model is confirmed by the experimental results, with less than 7% error in measurements of both diaphragm displacement and lung volume. Finally, the magnitude of robotic assistive forces positively correlates with diaphragm movement, while the shape of the forces shows no significant relationship with diaphragm activity.ConclusionOur experimental findings validate the effective assistance mechanism of the proposed robot, which enhances diaphragm mobility and assists in ventilation through extracorporeal robotic intervention. This robotic system can assist with ventilation while increasing diaphragm mobility, potentially resolving the issue of diaphragm atrophy. Additionally, this work paves the way for improved robotic designs and personalized assistance, tailored to the dynamics of the diaphragm in respiratory rehabilitation.
The effects of Qingchang Ligan formula on hepatic encephalopathy in mouse model: results from gut microbiome-metabolomics analysis
Authors: Yang Ziwei , Liu Shuhui , Wei Feili , Hu Jianhua 
Published: August 2024

BackgroundHepatic encephalopathy (HE) is a neurological disorder resulting from advanced liver injury. HE has a high mortality rate and poor prognosis. The pathogenesis of HE is still unclear, which has led to the lack of a satisfactory specific treatment method. There is increasing evidence that the intestinal flora affects the communication between the gut and the brain in the pathogenesis of HE. Adjusting the intestinal flora has had a beneficial effect on HE in recent studies, and the Qingchang Ligan formula (QCLG) has been shown in previous studies to regulate intestinal flora and metabolites. In this study, we established a thioacetamide-induced HE mouse model to evaluate the protective effect of QCLG on HE and explore its potential mechanism, which also demonstrated that intestinal flora dysbiosis is involved in the pathogenesis of HE.MethodsMice were intraperitoneally injected with thioacetamide (TAA, 150 mg/kg) to induce HE. Additionally, they were orally administered Qingchang Ligan Formula (QCLG) at a dose of 6.725 g/kg·d for seven days, while control mice received an equal volume of saline via gavage. Subsequently, samples were subjected to 16S ribosomal ribonucleic acid (rRNA) gene sequencing, high-performance liquid chromatography-mass spectrometry (LC-MS), and RNA-sequencing (RNA-seq) analysis.ResultQCLG improved weight loss, cognitive impairment, neurological function scores, blood ammonia, and brain gene expression of interleukin-6 (TNF-α), Interleukin-1β (IL-1β), and interleukin-6 (IL-6) induced by HE. Moreover, QCLG increased the levels of liver function indicators, including alanine aminotransferase (ALT), aspartate aminotransferase (AST), and serum TNF-α, IL-1β, and IL-6. 16S RNA sequencing revealed increased Oscillibacter, Colidextribacter, and Helicobacter in TAA-induced mouse fecal samples. Also, the abundance of Bifidobacterium decreases TAA-induced mouse fecal samples. In contrast, QCLG treatment significantly restored the gut microbial community. Metabolomics indicated significant differences in some metabolites among the normal control, treatment, and model groups, including 5-methoxytryptophan, Daidzein, Stercobilin, and Plumieride (PLU).ConclusionQCLG can alleviate neuroinflammation and prevent HE caused by liver injury by regulating intestinal flora in mouse models.
Variation in internode length patterns: a data analysis of internode length and serial number in three bamboo species
Authors: Tan Jiewen , Liu Xiaonan , Li Qiying , Ma Kehang , Huang Weiwei 
Published: August 2024

IntroductionBamboo is one of the fastest-growing plants on earth, and its young culms are formed by the elongation of internodes. However, the mathematical intricacies of its internode elongation are not well understood.MethodsThis study investigated the internode length growth of Phyllostachys edulis, Phyllostachys iridescens, and Pseudosasa amabilis at ten different culm height developmental stages (G1–G10).Results and discussionThe tempo of internode elongation from the culm base to the tip generally followed a “slow-fast-slow” growth rhythm. The internode length and the serial number relationship showed a right-skewed curve. As the bamboo grows taller, the longest internode moves from the base to the middle of the culm. The relationship between relative internode number (RIN) and relative cumulative internode length (RCIL) displayed a typical S-shaped growth curve. The modified Brière (MBE) sigmoid equation achieved better goodness-of-fit than the logistic, power, and third-order functions in fitting the RIN-RCIL curves with the smallest average root mean square error (RMSE). The elongation rates of internodes varied not only with the growth of culm height, but also with the position of the bamboo culm from base to tip. In addition, as the bamboo grows in height, more internodes gradually contribute to the culm height growth. At G1 development stage, 24.01–38.23% of the internodes contributed 65.27–73.59% of the culm height, whereas at G10 stage, 49.28–61.07% of the internodes contributed 66.70–78.18% of the culm height. Our findings provide new insights into the mathematical characterization of bamboo internode elongation patterns involved in the rapid culm growth.
A multidisciplinary non-invasive approach to monitor response to intravenous immunoglobulin treatment in neurodegenerative Langerhans cell histiocytosis: a real-world study
Authors: Trambusti Irene , Barba Carmen , Mortilla Marzia , Rizzi Susanna , Romano Katiuscia , Coniglio Maria Luisa , Lucenteforte Ersilia , Tondo Annalisa , Guerrini Renzo , Sieni Elena 
Published: August 2024

AimsEarly detection and treatment of neurodegenerative Langerhans cell histiocytosis (ND-LCH) have been suggested to prevent neurodegenerative progression. The aim of the study is to validate a standardized multidisciplinary diagnostic work-up to monitor the intravenous immunoglobulins (IVIG) treatment response and the natural course of the disease in untreated patients.MethodsPatients with abnormal somatosensory evoked potentials (SEPs) received monthly 0.5 g/kg IVIG. The diagnostic protocol included structural 3T MRI, neurological examination, brainstem auditory evoked potentials (BAEPs) and SEPs.ResultsTwenty-two patients were followed for 5.2 years (median) from the first MRI evidence of ND-LCH. Eleven patients received IVIG for 1.7 years (median). At treatment start neurological examination was abnormal in 10 patients, of whom two had severe clinical impairment and four had abnormal BAEPs. At last follow-up, 1/11 remained stable and 7/11 improved, while worsening of neurological or neurophysiological findings, or both, occurred in 3/11. Risk factors for worsening were a severe clinical or MRI ND-LCH at treatment initiation and prolonged exposure to LCH. Of the 11 untreated patients, none improved and three worsened.ConclusionsUsing a standardized diagnostic protocol, we demonstrated that IVIG treatment can lead to clinical stabilization or improvement in all pauci-symptomatic patients with an MRI grading of less than 4.
Multi-omics analysis reveals the impact of influenza a virus host adaptation on immune signatures in pig tracheal tissue
Authors: Laybourn Helena Aagaard , Hellemann Polhaus Chrysillis , Kristensen Charlotte , Lyngfeldt Henriksen Betina , Zhang Yaolei , Brogaard Louise , Larsen Cathrine Agnete , Trebbien Ramona , Larsen Lars Erik , Kalogeropoulos Konstantinos , auf dem Keller Ulrich , Skovgaard Kerstin 
Published: August 2024

IntroductionInfluenza A virus (IAV) infection is a global respiratory disease, which annually leads to 3-5 million cases of severe illness, resulting in 290,000-650,000 deaths. Additionally, during the past century, four global IAV pandemics have claimed millions of human lives. The epithelial lining of the trachea plays a vital role during IAV infection, both as point of viral entry and replication as well as in the antiviral immune response. Tracheal tissue is generally inaccessible from human patients, which makes animal models crucial for the study of the tracheal host immune response.MethodIn this study, pigs were inoculated with swine- or human-adapted H1N1 IAV to gain insight into how host adaptation of IAV shapes the innate immune response during infection. In-depth multi-omics analysis (global proteomics and RNA sequencing) of the host response in upper and lower tracheal tissue was conducted, and results were validated by microfluidic qPCR. Additionally, a subset of samples was selected for histopathological examination.ResultsA classical innate antiviral immune response was induced in both upper and lower trachea after infection with either swine- or human-adapted IAV with upregulation of genes and higher abundance of proteins associated with viral infection and recognition, accompanied by a significant induction of interferon stimulated genes with corresponding higher proteins concentrations. Infection with the swine-adapted virus induced a much stronger immune response compared to infection with a human-adapted IAV strain in the lower trachea, which could be a consequence of a higher viral load and a higher degree of inflammation.DiscussionCentral components of the JAK-STAT pathway, apoptosis, pyrimidine metabolism, and the cytoskeleton were significantly altered depending on infection with swine- or human-adapted virus and might be relevant mechanisms in relation to antiviral immunity against putative zoonotic IAV. Based on our findings, we hypothesize that during host adaptation, IAV evolve to modulate important host cell elements to favor viral infectivity and replication.
Spatial patterns of microparticle ingestion by myctophids near a major river mouth in the northeast Pacific Ocean
Authors: Boisen Olivia C. , Brodeur Richard D. , Brander Susanne M. , Heppell Scott A. 
Published: August 2024

IntroductionPlastics carried in the outflow of major rivers can be made available and subsequently ingested by marine fishes, causing lethal and sublethal effects. Highly abundant, vertically migrating myctophids play a crucial role in facilitating nutrient cycling between the epi- and mesopelagic zones. However, this diel movement may also make myctophids significant conduits for transporting ingested microparticles from surface waters to deeper food webs. MethodsWe examined the gastrointestinal tracts of 340 myctophids caught at varying distances from the Columbia River mouth in the epipelagic zone of the northeast Pacific Ocean to determine if proximity to a presumed point source influences microparticle ingestion. ResultsWhile we found no direct spatial connection with ingestion frequency, we discovered that (a) ~34% of myctophids had either synthetic or other anthropogenic particles retained in their GI tract, (b) microparticle ingestion was higher in an active-feeding species of myctophid (Tarletonbeania crenularis) than an inactive-feeding species (Stenobrachius leucopsarus), and (c) species and standard length were the most influential predictors of microparticle consumption in our best fit model. DiscussionOur failure to detect a significant relationship between distance from a source and ingestion by myctophids is likely due to the particles undergoing fluctuations in dispersal patterns once they enter the ocean, particularly for microfibers which can be transported across large distances. Biological factors like body size may be more relevant to understanding microparticle ingestion patterns in mesopelagic fishes. Overall, our study highlights the potential role myctophids serve as multidirectional transporters of microparticles in Northern California Current food webs, with potential impacts on fisheries and human food systems.
Frontiers and hotspots evolution in mild cognitive impairment: a bibliometric analysis of from 2013 to 2023
Authors: He Chunying , Hu Xiaohua , Wang Muren , Yin Xiaolan , Zhan Min , Li Yutong , Sun Linjuan , Du Yida , Chen Zhiyan , Wang Huan , Shao Haibin 
Published: August 2024

BackgroundMild cognitive impairment is a heterogeneous syndrome. The heterogeneity of the syndrome and the absence of consensus limited the advancement of MCI. The purpose of our research is to create a visual framework of the last decade, highlight the hotspots of current research, and forecast the most fruitful avenues for future MCI research.MethodsWe collected all the MCI-related literature published between 1 January 2013, and 24 April 2023, on the “Web of Science.” The visual graph was created by the CiteSpace and VOSviewer. The current research hotspots and future research directions are summarized through the analysis of keywords and co-cited literature.ResultsThere are 6,075 articles were included in the final analysis. The number of publications shows an upward trend, especially after 2018. The United States and the University of California System are the most prolific countries and institutions, respectively. Petersen is the author who ranks first in terms of publication volume and influence. Journal of Alzheimer’s Disease was the most productive journal. “neuroimaging,” “fluid markers,” and “predictors” are the focus of current research, and “machine learning,” “electroencephalogram,” “deep learning,” and “blood biomarkers” are potential research directions in the future.ConclusionThe cognition of MCI has been continuously evolved and renewed by multiple countries’ joint efforts in the past decade. Hotspots for current research are on diagnostic biomarkers, such as fluid markers, neuroimaging, and so on. Future hotspots might be focused on the best prognostic and diagnostic models generated by machine learning and large-scale screening tools such as EEG and blood biomarkers.
Nicotine use during late adolescence and young adulthood is associated with changes in hippocampal volume and memory performance
Authors: Happer Joseph P. , Courtney Kelly E. , Baca Rachel E. , Andrade Gianna , Thompson Courtney , Shen Qian , Liu Thomas T. , Jacobus Joanna 
Published: August 2024

BackgroundWith the advent of electronic nicotine delivery systems, the use of nicotine and tobacco products (NTPs) among adolescents and young adults remains high in the US. Use of e-cigarettes additionally elevates the risk of problematic use of other substances like cannabis, which is often co-used with NTPs. However, their effects on brain health, particularly the hippocampus, and cognition during this neurodevelopmental period are poorly understood.MethodsHealthy late adolescents/young adults (N = 223) ages 16–22 completed a structural MRI to examine right and left hippocampal volumes. Memory was assessed with the NIH Toolbox Picture Sequence Memory Test (PSMT) and Rey Auditory Verbal Learning Test (RAVLT). Cumulative 6-month NTP and cannabis episodes were assessed and modeled continuously on hippocampal volumes. Participants were then grouped based on 6-month NTP use to examine relationships with the hippocampus and memory: current users (CU) endorsed weekly or greater use; light/abstinent users (LU) endorsed less than weekly; and never users (NU).ResultsNTP use predicted larger hippocampal volumes bilaterally while cannabis use had no impact nor interacted with NTP use. For memory, larger left hippocampal volumes were positively associated with PSMT performance, RAVLT total learning, short delay and long delay recall for the NU group. In contrast, there was a negative relationship between hippocampal volumes and performances for LU and CU groups. No differences were detected between NTP-using groups.ConclusionThese results suggest that the hippocampus is sensitive to NTP exposure during late adolescence/young adulthood and may alter typical hippocampal morphometry in addition to brain-behavior relationships underlying learning and memory processes.