bluuebunny/crossref_metadata_2025_split huggingface dataset:
Constraint-handling techniques for generative product design systems in the mass customization context
Authors: Nordin Axel , Motte Damien , Hopf Andreas , Bjärnemo Robert , Eckhardt Claus-Christian 
Published: October 2013

AbstractGenerative product design systems used in the context of mass customization are required to generate diverse solutions quickly and reliably without necessitating modification or tuning during use. When such systems are employed to allow for the mass customization ofproduct form, they must be able to handle mass production and engineering constraints that can be time-consuming to evaluate and difficult to fulfill. These issues are related to how the constraints are handled in the generative design system. This article evaluates two promising sequential constraint-handling techniques and the often used weighted sum technique with regard to convergence time, convergence rate, and diversity of the design solutions. The application used for this purpose was a design system aimed at generating a table with an advanced form: a Voronoi diagram based structure. The design problem was constrained in terms of production as well as stability, requiring a time-consuming finite element evaluation. Regarding convergence time and rate, one of the sequential constraint-handling techniques performed significantly better than the weighted sum technique. Nevertheless, the weighted sum technique presented respectable results and therefore remains a relevant technique. Regarding diversity, none of the techniques could generate diverse solutions in a single search run. In contrast, the solutions from different searches were always diverse. Solution diversity is thus gained at the cost of more runs, but no evaluation of the diversity of the solutions is needed. This result is important, because a diversity evaluation function would otherwise have to be developed for every new type of design. Efficient handling of complex constraints is an important step toward mass customization of nontrivial product forms.
Multivariate Pattern Analysis of fMRI in Breast Cancer Survivors and Healthy Women
Authors: Hosseini S.M. Hadi , Kesler Shelli R. 
Published: October 2013

AbstractAdvances in breast cancer (BC) treatments have resulted in significantly improved survival rates. However, BC chemotherapy is often associated with several side effects including cognitive dysfunction. We applied multivariate pattern analysis (MVPA) to functional magnetic resonance imaging (fMRI) to find a brain connectivity pattern that accurately and automatically distinguishes chemotherapy-treated (C+) from non-chemotherapy treated (C−) BC females and healthy female controls (HC). Twenty-seven C+, 29 C−, and 30 HC underwent fMRI during an executive-prefrontal task (Go/Nogo). The pattern of functional connectivity associated with this task discriminated with significant accuracy between C+ and HC groups (72%, p = .006) and between C+ and C− groups (71%, p = .012). However, the accuracy of discrimination between C− and HC was not significant (51%, p = .46). Compared with HC, behavioral performance of the C+ and C− groups during the task was intact. However, the C+ group demonstrated altered functional connectivity in the right frontoparietal and left supplementary motor area networks compared to HC, and in the right middle frontal and left superior frontal gyri networks, compared to C−. Our results provide further evidence that executive function performance may be preserved in some chemotherapy-treated BC survivors through recruitment of additional neural connections. (JINS, 2013, 19, 1–11)
Climate Engineering in Global Climate Governance: Implications for Participation and Linkage
Authors: Parson Edward A. 
Published: October 2013

AbstractThe prospect of climate engineering (CE) – also known as geoengineering, referring to modification of the global environment to partly offset climate change and impacts from elevated atmospheric greenhouse gases – poses major, disruptive challenges to international policy and governance. If full global cooperation to manage climate change is not initially achievable, adding CE to the agenda has major effects on the challenges and risks associated with alternative configurations of participation – for example, variants of partial cooperation, unilateral action, and exclusion. Although the risks of unilateral CE by small states or non-state actors have been over-stated, some powerful states may be able to pursue CE unilaterally, risking international destabilization and conflict. These risks are not limited to future CE deployment, but may also be triggered by unilateral research and development (R&D), secrecy about intentions and capabilities, or assertion of legal rights of unilateral action. They may be reduced by early cooperative steps, such as international collaboration in R&D and open sharing of information. CE presents novel opportunities for explicit bargaining linkages within a complete climate response. Four CE-mitigation linkage scenarios suggest how CE may enhance mitigation incentives, and not weaken them as commonly assumed. Such synergy appears to be challenging if CE is treated only as a contingent response to a future climate crisis, but may be more achievable if CE is used earlier and at lower intensity, either to reduce peak near-term climate disruption in parallel with a programme of deep emission cuts or to target regional climate processes linked to acute global risks.
Bone morphogenetic protein-9 inhibits lymphatic vessel formation via activin receptor-like kinase 1 during development and cancer progression
Authors: Yoshimatsu Yasuhiro , Lee Yulia G. , Akatsu Yuichi , Taguchi Luna , Suzuki Hiroshi I. , Cunha Sara I. , Maruyama Kazuichi , Suzuki Yuka , Yamazaki Tomoko , Katsura Akihiro , Oh S. Paul , Zimmers Teresa A. , Lee Se-Jin , Pietras Kristian , Koh Gou Young , Miyazono Kohei , Watabe Tetsuro 
Published: October 2013

Significance
Because lymphatic vessels (LVs) play critical roles not only in physiological processes such as maintenance of fluid homeostasis but also in pathological conditions including cancer metastasis, identification of factors that control LV formation is crucial. Signals mediated by activin receptor-like kinase 1 (ALK-1), a receptor for bone morphogenetic protein 9 (BMP-9), have been implicated in the formation of blood vessels because of its linkage to a human vascular disease. However, their roles in LV formation largely remain to be elucidated. Here, we show that BMP-9/ALK-1 signals inhibit LV formation in physiological and pathological conditions. Furthermore, we elucidated its molecular mechanisms in detail, using both in vivo and in vitro systems. These findings will help develop therapeutic strategies for LV-related diseases such as lymphedema and cancer.
Fast structural responses of gap junction membrane domains to AB5 toxins
Authors: Majoul Irina V. , Gao Liang , Betzig Eric , Onichtchouk Daria , Butkevich Eugenia , Kozlov Yuri , Bukauskas Feliksas , Bennett Michael V. L. , Lippincott-Schwartz Jennifer , Duden Rainer 
Published: October 2013

Significance
We used 3D Bessel beam plane illumination and spinning disk microscopy to reveal fast structural changes in the architecture of gap junctions (GJs). Previously, GJ plaques were considered relatively stable structures. We demonstrate extremely rapid remodeling of proteins and lipids within GJ plaques in response to bacterial toxin exposure. Connexin channels within GJ plaques undergo dramatic rearrangements that lead to increased connexin packing and lipid reorganization. These changes likely reflect lipid-phase separation events in the biological membrane. Toxin-induced connexin reorganization depends on lipids and is little modified by membrane–cytoskeletal interactions. We suggest that fast GJ changes upon toxin exposure reveal an early-response system of cells and that GJ plaques are much more dynamic structures than previously recognized.
Prospects for Fishery-Induced Collapse of Invasive Asian Carp in the Illinois River
Authors: Tsehaye Iyob , Catalano Matthew , Sass Greg , Glover David , Roth Brian 
Published: October 2013

ABSTRACT
Invasive Asian Carp are threatening to enter Lake Michigan through the Chicago Area Waterway System, with potentially serious consequences for Great Lakes food webs. Alongside efforts to keep these fishes from entering Lake Michigan with electric barriers, the state of Illinois initiated a fishing program aimed at reducing their densities through intensive commercial exploitation on the Illinois River. In this study, we explore prospects for the “collapse” of Asian Carp in the Illinois River through intensive fishing. Based on a meta-analysis of demographic data, we developed a dynamic simulation model to compare the performance of existing and alternative removal strategies for the Illinois River. Our model projections suggest that Asian Carp in the Illinois River are unlikely to collapse if existing harvest rates are kept below 0.7 or fishing continues to be size selective (targeting only fish &gt;500 mm or &lt;500 mm) or species selective (targeting mostly Bighead Carp), although their biomasses could be greatly reduced. We argue that it would still be possible to achieve fishing effort targets predicted by our model to collapse the Asian Carp populations if efforts to expand commercial fishing are combined with economic incentives to improve size selectivity and species targeting.
RESUMEN
La carpa asiática amenaza con invadir el Lago Michigan a través del sistema de vías acuáticas del área de Chicago, lo cual podría acarrear serias consecuencias en las tramas tróficas de los grandes lagos. Además de los esfuerzos llevados a cabo para impedir el ingreso de estos peces al Lago Michigan mediante barreras eléctricas, el estado de Illinois ha iniciado un programa de pesca en el Río Illinois, cuya finalidad es reducir la densidad poblacional a través de una pesca comercial intensiva. En este estudio se exploran los prospectos de un colapso de la carpa asiática por medio de un régimen de pesca intensiva. Sobre la base de un meta-análisis de datos demográficos, se desarrolla un modelo de simulación dinámica para comparar el desempeño de estrategias de explotación tanto reales como alternativas para el Río Illinois. Las proyecciones del modelo sugieren que, de mantenerse las tasas de captura por debajo de 0.7 o si la pesca continua siendo selectiva a tallas (dirigiéndose a peces &gt;500 mm o &lt;500 mm) o a especies (carpa cabezona), entonces es poco probable colapsar la carpa asiática en el Río Illinois, aunque la biomasa se puede reducir considerablemente. Se argumenta que, pese a lo anterior, es posible lograr el nivel de esfuerzo pesquero predicho por el modelo, necesario para colapsar las poblaciones de la carpa asiática, si la pesca comercial se expande y se combina con incentivos económicos con tal de mejorar la selectividad a la talla y a las especies objetivo.
Forming a Partnership to Avoid Bycatch
Authors: O'Keefe Catherine E , DeCelles Gregory R 
Published: October 2013

ABSTRACT
Bycatch of Yellowtail Flounder in the U.S. Sea Scallop Fishery is a constraint to achieving optimum yield of scallops. Between 2000 and 2009, in-season bycatch closures of prime scallop grounds resulted in economic losses over US$100 million. To address this constraint, we collaborated with the scallop fishing industry to implement a bycatch avoidance program in the Nantucket Lightship harvest area in 2010. Vessels shared near real-time location information about bycatch amounts during fishing activities. We compiled the information, identified bycatch hotspots, and provided daily advisories to vessels on the fishing grounds. Catch per tow of Yellowtail and fishing effort in high bycatch regions significantly declined after the fleet received the advisories. The fleet harvested the target scallop allocation worth US$40 million while catching only 32% of the Yellowtail bycatch limit. This program continues as a collaborative, iterative approach to bycatch reduction that balances fleet objectives with conservation constraints.
RESUMEN
En los EE.UU., la captura incidental de la platija amarilla es una limitante para que la pesquería de almeja alcance la captura óptima. Entre 2000 y 2009, las vedas estacionales de captura incidental en las áreas de pesca de la almeja produjeron pérdidas económicas por encima de los 100 millones de dólares. Con el fin de estudiar esta limitante, en 2010 se puso en marcha una colaboración con la industria pesquera de almeja para implementar un programa de evasión de la captura incidental en la zona de pesca de Nantucket Lightship. Las embarcaciones compartían, en tiempo real, la localización de regiones y volúmenes de captura incidental obtenidos durante las actividades de pesca. Se compiló la información, se identificaron las zonas clave de captura incidental y se brindaron asesorías diarias a las embarcaciones en las áreas de pesca. Tanto la captura por arrastre de la platija como el esfuerzo pesquero en regiones de alta captura incidental, se redujeron sustancialmente después de que las embarcaciones recibieran la asesoría. La captura de almejas en sitios selectos representó una ganancia de 40 millones de dólares, a la vez que se alcanzaba sólo el 32% del límite de captura incidental de la platija. Este programa continua como un enfoque colaborativo e iterativo para reducir la captura incidental de forma tal que se tienda a un balance entre los objetivos de la flota y las limitaciones que impone la conservación.
Smartphones and Digital Tablets: Emerging Tools for Fisheries Professionals
Authors: Gutowsky Lee F G , Gobin Jenilee , Burnett Nicholas J , Chapman Jacqueline M , Stoot Lauren J , Bliss Shireen 
Published: October 2013

ABSTRACT
Smartphones and digital tablets are used to collect data for agricultural, geographical, and medical research. Science professionals find these devices attractive because they contain many useful hardware accessories (e.g., camera, Global Positioning System [GPS], accelerometer) and the capacity to access and customize software applications (apps). To enhance student learning, some educators are also integrating tablets into curricula for both indoor and outdoor course work. Recently, fisheries professionals have begun using these devices for data collection and public outreach and awareness. With new waterproofing technology, cases, and peripheral adapters, smartphones and digital tablets are continually becoming more relevant for data collection and education in fisheries. Here, we synthesize some of the available information on smartphone and tablet use for data collection and education and explore some current uses and future opportunities for these devices in fisheries. Overall, our objective is to demonstrate that smartphones and digital tablets are useful tools for fisheries professionals, including technicians, managers, and educators.
RESUMEN
Los teléfonos inteligentes y las tabletas digitales se utilizan para colectar datos geográficos, de agricultura y de investigaciones médicas. Los profesionales de la ciencia encuentran atractivos estos dispositivos porque contienen accesorios útiles de hardware (p.e. cámaras, sistemas de posicionamiento geográfico –GPS-, acelerómetros, etc.) y además son capaces de brindar acceso y configurar aplicaciones de software (apps). Con el fin de mejorar el aprendizaje de los estudiantes, algunos educadores están integrando las tabletas digitales en las matrículas tanto dentro como fuera de los salones de clases. Recientemente, los profesionales de las pesquerías han comenzado a usar estos dispositivos para colectar datos, para difusión y concientización. Con nueva tecnología submarina, cubiertas y adaptadores periféricos, los teléfonos inteligentes y las tabletas digitales están volviéndose cada vez más relevantes para educación y para colectar datos pesqueros. En este estudio se resume parte de la información disponible en lo tocante al uso de teléfonos inteligentes y tabletas digitales con fines educativos y de recolecta de datos. También se exploran algunos usos actuales y oportunidades futuras que guardan estos dispositivos para la ciencia pesquera. El principal objetivo es demostrar que los teléfonos inteligentes y las tabletas digitales son herramientas útiles para los profesionales de las pesquerías, incluyendo técnicos, manejadores y educadores.
Rapid Ammonia Gas Transport Accounts for Futile Transmembrane Cycling under NH3/NH4
+ Toxicity in Plant Roots
Authors: Coskun Devrim , Britto Dev T. , Li Mingyuan , Becker Alexander , Kronzucker Herbert J. 
Published: October 2013

Abstract
Futile transmembrane NH3/NH4 + cycling in plant root cells, characterized by extremely rapid fluxes and high efflux to influx ratios, has been successfully linked to NH3/NH4 + toxicity. Surprisingly, the fundamental question of which species of the conjugate pair (NH3 or NH4 +) participates in such fluxes is unresolved. Using flux analyses with the short-lived radioisotope 13N and electrophysiological, respiratory, and histochemical measurements, we show that futile cycling in roots of barley (Hordeum vulgare) seedlings is predominately of the gaseous NH3 species, rather than the NH4 + ion. Influx of 13NH3/13NH4 +, which exceeded 200 µmol g–1 h–1, was not commensurate with membrane depolarization or increases in root respiration, suggesting electroneutral NH3 transport. Influx followed Michaelis-Menten kinetics for NH3 (but not NH4 +), as a function of external concentration (K m = 152 µm, V max = 205 µmol g–1 h–1). Efflux of 13NH3/13NH4 + responded with a nearly identical K m. Pharmacological characterization of influx and efflux suggests mediation by aquaporins. Our study fundamentally revises the futile-cycling model by demonstrating that NH3 is the major permeating species across both plasmalemma and tonoplast of root cells under toxicity conditions.
MYb(BH4)4(M= K, Na) from laboratory X-ray powder data
Authors: Wegner Wojciech , Jaroń Tomasz , Grochala Wojciech 
Published: October 2013

Two new borohydrides, potassium ytterbium tetraborohydride, KYb(BH4)4, and sodium ytterbium tetraborohydride, NaYb(BH4)4, have been synthesizedviamechanochemical reactions in the solid state. The two compounds are isostructural and both crystallize in theCmcmspace group in the structure reported previously for NaSc(BH4)4and KY(BH4)4. This crystal structure is composed of isolated homoleptic [Yb(BH4)4]−anions surrounded byM+cations (M = Na, K). The packing of theM+cations and [Yb(BH4)4]−anions is a distorted variant of the hexagonal NiAs structure type, withM+forming distorted trigonal prisms,i.e.M6. Each second prism surrounds a [Yb(BH4)4]−anion, while the [Yb(BH4)4]−anions are arranged into deformed octahedra around theM+cations.
Shariah supervisory system in Islamic financial institutions
Authors: Grassa Rihab 
Published: October 2013

Purpose
– The aim of this paper is to review the different steps of development of Shariah governance system and to discuss the different practices of Shariah governance in Islamic financial institutions internationally.

Design/methodology/approach
– The paper has a particular focus on the other contributions of relevant literature and existing laws and regulations for Islamic financial institutions which provides a reflective synthesis on practical work of Shariah governance system across different jurisdictions.

Findings
– The main attention of this paper is Islamic financial institutions and a key issue arising is that the typical structure, functions, duties and responsibilities are different from country to country.

Practical implications
– The paper put forward various suggestions to the regulatory authorities and to the Islamic Financial Services Board to enhance the Shariah governance system and to standardize the different practices of Shariah governance worldwide.

Originality/value
– The originality and the value of the paper lie in its critical review of current Shariah governance practices worldwide. As well, some key issues pertaining to Shariah governance in Islamic financial institutions are addressed to encourage further investigation by academics and practitioners in the field.
Myths of exponential growth in populations and wealth: an emergent perspective
Authors: R. Yezdani Omer 
Published: October 2013

Purpose
– The purpose of this paper is to highlight the dilemma of exponential growth in economic policy and its implications on sustainable development.

Design/methodology/approach
– The future of the world economy is premised in part on the assumption of an implicit law of increasing returns that has remained unchanged for centuries. Drawing on current data in per capita gross domestic product and population data, this paper explores the relationship between growth in populations and the distribution of wealth. Implications on economic and social policy reform are discussed, with an exemplar focus on economic incentives employed in several nations that are premised on an assumed relationship between population growth and economic return.

Findings
– This paper demonstrates that much of current economic and social policy is grounded in centuries-old assumptions that may be inadequate for today's highly interrelated global and economic society, and that changing these policies would require a fundamental shift of mindset to recognise domestic human values within a global context.

Originality/value
– Previous literature has paid less attention to the underlying assumptions of perpetual growth inherent to social and economic policy and the practicalities of its reconceptualization on global society.
Applying IT governance balanced scorecard and importance-performance analysis for providing IT governance strategy in university
Authors: Jairak Kallaya , Praneetpolgrang Prasong 
Published: October 2013

Purpose
– The purpose of this paper is to identify the current situation and the future improvement for IT governance and controls in developing country like Thailand.

Design/methodology/approach
– Thai universities were selected and used as subjects for capturing the perception of IT executives on IT governance performance measures. In the first step, a global IT governance perspective was drawn from the literature review. In the second step, the important-performance analysis was applied to the metrics of IT governance balanced scorecard with collected survey data from 64 IT executives.

Findings
– From a global perspective, the critical points that need to be concerned before implementing IT governance have been illustrated. From a regional perspective, the paper generated the strategic IT governance guidance for Thai universities.

Practical implications
– This paper is beneficial for chief information officers, executive managers, IT managers, and academics. They will gain more knowledge and understanding about the mixed method of using metrics in IT governance balanced scorecard and importance-performance analysis in order to identify the current situation of IT governance and controls in their organizations. Additionally, the practical idea with this method can be applied to draw IT governance strategy in their contexts.

Originality/value
– This paper specifies the critical points and directions of IT governance for Thai universities. The analysis covers global and regional viewpoints. This paper also provides the method for applying IT governance balanced scorecard metrics and importance-performance analysis to contribute IT governance strategy.