bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nurturing Resilient Generations: Character Education in Islamic Teachings within the Framework of Society 5.0
Authors: Irlina Andi , Barni Mahyuddin , Basir Abd. , Khairuddin  
Published: July 2024

In the 4.0 industrial revolution era, people need to be technology literate. This is carried out in light of the fact that people frequently utilize technology to make a variety of tasks or activities easier, including educational tasks. Technology can also help societies in a country to meet other societies around the words using varieties of social media platforms. Technology enlighten the 5.0 society’s task, but the existence of digital technology also causes children and teenagers to face a variety of issues; it impedes their development and progress, and it leads to negative behavior among children and teenagers. Violence, online gambling, free sex, killing for the sake of money, even, and suicide. In the 5.0 society era, however, a resilient generation is required. We need human resources that can not only utilize technology to make life easier but also use it to benefit people and the environment in order to meet the challenges of this new era. Qualitative methodologies and a literature review are used in this study. For this study, the author gathers and examines information from a number of trustworthy sources. The study's findings suggest that teaching Islamic character building education to children and teenagers is essential to prepare them to be resilient adults. Islam teaches about morality, adab, seerah, muroqabalah, worship, and monotheism. Communities, families, and educational institutions as well as the government can work together to establish character education initiatives that are in line with Islamic beliefs. Islamic character education offer insights into developing a resilient mindset that withstands technology disruptions and societal upheavals by utilizing a holistic viewpoint that takes into account people's spiritual, intellectual, and emotional aspects resulting resilient generations.
Leonor Fini e Milena Pavlović Barilli, italiennes de Paris alle Quadriennali d’arte di Roma (1931-1939): «accese creatrici d’intense e misteriose figure»
Authors: Carrieri Rosanna 
Published: July 2024

Nell’occasione delle prime quattro Quadriennali d’arte di Roma, tenutesi durante il Ventennio e orchestrate da Cipriano Efisio Oppo, numerose sono le partecipazioni femminili di profili artistici ad oggi in parte ancora inesplorati. Tra queste artiste, emergono Leonor Fini e Milena Pavlović Barilli, distintesi nel contesto per la loro apertura internazionale. La presenza in Quadriennale – rispettivamente per Fini alla prima (1931) e alla seconda edizione (1935), per Pavlović Barilli alla seconda e alla terza (1939) – si colloca in un momento di vicinanza con il gruppo degli italiani a Parigi, dove entrambe risiedono in quegli anni. L’articolo si propone di delineare aspetti specifici legati alla loro partecipazione all’esposizione romana, rintracciando opere esposte e recuperando una parte del dibattito critico, con l’obiettivo di contribuire al rinnovato interesse rivolto alla presenza in Italia delle due artiste.
Pengalaman fatherhood pada ayah yang menikah pada usia remaja di Kabupaten Ogan Komering Ulu Sumatera Selatan
Authors: Zahra Tamela , Wuri Astuti Andari 
Published: July 2024

Latar Belakang: Menjadi ayah di usia remaja merupakan suatu critical period. Critical period yang dialami adalah menjadi remaja dan juga menjadi ayah. Transisi menjadi ayah di usia remaja berdampak besar pada kehidupan ayah remaja. Tujuan: Untuk mengetahui pengalaman fatherhood pada ayah yang menikah pada usia remaja di Kabupaten Ogan Komering Ulu. Metode: Penelitian kualitatif dengan pendekatan generic qualitative. Teknik pengambilan partisipan adalah purposive sampling dan snowball sampling. Partisipan dalam penelitian ini adalah ayah yang menikah pada usia remaja yang berjumlah 6 partisipan. Pengumpulan data dengan menggunakan metode one-to-one in-depth interview. Analisis data menggunakan analisis tematik. Hasil: Dari hasil penelitian didapatkan 5 tema yaitu, pengalaman pernikahan dari sudut pandang ayah remaja, kehidupan ayah remaja, konsep fatherhood, dukungan dan harapan, kebutuhan. Proses transisi menjadi ayah memiliki sisi positif dan negatif bagi ayah remaja. Sisi positif adalah perubahan yang lebih baik dan sisi negatif adalah Ayah remaja rentan mengalami masalah ekonomi dan kesulitan beradaptasi dengan peran baru. Simpulan: Ayah remaja memiliki kesulitan untuk beradaptasi dengan peran baru. Dukungan, arahan dan edukasi diperlukan ayah remaja untuk menghadapi peran barunya agar proses transisinya berjalan dengan baik.
GATIS score for predicting the prognosis of rectal neuroendocrine neoplasms: A Chinese multicenter study of 12-year experience
Authors: Zeng Xin-Yu , Zhong Ming , Lin Guo-Le , Li Cheng-Guo , Jiang Wei-Zhong , Zhang Wei , Xia Li-Jian , Di Mao-Jun , Wu Hong-Xue , Liao Xiao-Feng , Sun Yue-Ming , Yu Min-Hao , Tao Kai-Xiong , Li Yong , Zhang Rui , Zhang Peng 
Published: July 2024

BACKGROUND
There is currently a shortage of accurate, efficient, and precise predictive instruments for rectal neuroendocrine neoplasms (NENs).
AIM
To develop a predictive model for individuals with rectal NENs (R-NENs) using data from a large cohort.
METHODS
Data from patients with primary R-NENs were retrospectively collected from 17 large-scale referral medical centers in China. Random forest and Cox proportional hazard models were used to identify the risk factors for overall survival and progression-free survival, and two nomograms were constructed.
RESULTS
A total of 1408 patients with R-NENs were included. Tumor grade, T stage, tumor size, age, and a prognostic nutritional index were important risk factors for prognosis. The GATIS score was calculated based on these five indicators. For overall survival prediction, the respective C-indexes in the training set were 0.915 (95% confidence interval: 0.866-0.964) for overall survival prediction and 0.908 (95% confidence interval: 0.872-0.944) for progression-free survival prediction. According to decision curve analysis, net benefit of the GATIS score was higher than that of a single factor. The time-dependent area under the receiver operating characteristic curve showed that the predictive power of the GATIS score was higher than that of the TNM stage and pathological grade at all time periods.
CONCLUSION
The GATIS score had a good predictive effect on the prognosis of patients with R-NENs, with efficacy superior to that of the World Health Organization grade and TNM stage.
Effects of elafibranor on liver fibrosis and gut barrier function in a mouse model of alcohol-associated liver disease
Authors: Koizumi Aritoshi , Kaji Kosuke , Nishimura Norihisa , Asada Shohei , Matsuda Takuya , Tanaka Misako , Yorioka Nobuyuki , Tsuji Yuki , Kitagawa Koh , Sato Shinya , Namisaki Tadashi , Akahane Takemi , Yoshiji Hitoshi 
Published: July 2024

BACKGROUND
Alcohol-associated liver disease (ALD) is a leading cause of liver-related morbidity and mortality, but there are no therapeutic targets and modalities to prevent ALD-related liver fibrosis. Peroxisome proliferator activated receptor (PPAR) α and δ play a key role in lipid metabolism and intestinal barrier homeostasis, which are major contributors to the pathological progression of ALD. Meanwhile, elafibranor (EFN), which is a dual PPARα and PPARδ agonist, has reached a phase III clinical trial for the treatment of metabolic dysfunction-associated steatotic liver disease and primary biliary cholangitis. However, the benefits of EFN for ALD treatment is unknown.
AIM
To evaluate the inhibitory effects of EFN on liver fibrosis and gut-intestinal barrier dysfunction in an ALD mouse model.
METHODS
ALD-related liver fibrosis was induced in female C57BL/6J mice by feeding a 2.5% ethanol (EtOH)-containing Lieber-DeCarli liquid diet and intraperitoneally injecting carbon tetrachloride thrice weekly (1 mL/kg) for 8 weeks. EFN (3 and 10 mg/kg/day) was orally administered during the experimental period. Histological and molecular analyses were performed to assess the effect of EFN on steatohepatitis, fibrosis, and intestinal barrier integrity. The EFN effects on HepG2 lipotoxicity and Caco-2 barrier function were evaluated by cell-based assays.
RESULTS
The hepatic steatosis, apoptosis, and fibrosis in the ALD mice model were significantly attenuated by EFN treatment. EFN promoted lipolysis and β-oxidation and enhanced autophagic and antioxidant capacities in EtOH-stimulated HepG2 cells, primarily through PPARα activation. Moreover, EFN inhibited the Kupffer cell-mediated inflammatory response, with blunted hepatic exposure to lipopolysaccharide (LPS) and toll like receptor 4 (TLR4)/nuclear factor kappa B (NF-κB) signaling. EFN improved intestinal hyperpermeability by restoring tight junction proteins and autophagy and by inhibiting apoptosis and proinflammatory responses. The protective effect on intestinal barrier function in the EtOH-stimulated Caco-2 cells was predominantly mediated by PPARδ activation.
CONCLUSION
EFN reduced ALD-related fibrosis by inhibiting lipid accumulation and apoptosis, enhancing hepatocyte autophagic and antioxidant capacities, and suppressing LPS/TLR4/NF-κB-mediated inflammatory responses by restoring intestinal barrier function.
Les ficelles du métier en contexte contraint : regards sur le travail des conseillers dans le cadre du conseilen évolution professionnelle
Authors: Négroni Catherine 
Published: July 2024

Cette proposition interroge les changements introduits par le conseil en évolution professionnelle (CEP) dans l’accompagnement des parcours professionnels. Nous souhaitons questionner le métier de conseiller en évolution professionnelle et plus particulièrement l’injonction faite aux conseillers d’apprendre aux bénéficiaires à s’orienter en autonomie (Négroni et Lo, 2017), un objectif qui oscille entre deux pôles : celui de générer le développement professionnel et celui de sécuriser par l’employabilité les parcours professionnels des bénéficiaires. Nous proposons de confronter le cadre théorique des ficelles du métier de Howard Becker (2002) à la professionnalisation en acte des conseillers en évolution professionnelle. Il s’agit de déconstruire les modes d’accompagnement des conseillers, de comprendre ce qui se joue dans cette interaction sociale (Dewey, 1916), de repérer des récurrences dans les modalités d’action qui apparaîtraient en situation d’expérience et d’activité professionnelle, afin de révéler les enjeux instrumentaux et sociétaux que montre l’accompagnement (Jorro, 2019).
Implementation of MOVIN by a Nurse-Led Clinical Team: A Multiple Methods Evaluation Using the RE-AIM Framework
Authors: King Barbara , Hook Mary , Brown Roger , Mahoney Jane , Steege Linsey 
Published: July 2024

Purpose:
To evaluate the implementation of MOVIN, a multicomponent mobility intervention, by a nurse-led team and measure the effectiveness on unit-level outcomes.

Method:
A pragmatic quasi-experimental study was conducted on an inpatient adult medical unit. Evaluation was guided by the Reach, Effectiveness, Adoption, Implementation, and Maintenance (RE-AIM) framework. Interviews with 13 organizational partners were conducted to understand barriers and facilitators to adoption. Thematic analysis was used to analyze the data. Quantitative data to determine effectiveness on distance of patient ambulation and percent of patients ambulated by nursing staff were analyzed using an interrupted time series.

Results:

A significant increase in total weekly distances for patient ambulation and percent of patients ambulated by nursing staff occurred between preintervention, intervention, and postintervention periods. Themes for adoption included:
Value
,
Immediate Feedback
,
Inclusive Implementation
,
Resource Needs
, and
Lack of Organizational Evidence
. The nurse-led team demonstrated high fidelity to maintaining the core components of MOVIN.

Conclusion:

A nurse-led team can successfully launch a multicomponent mobility intervention and sustain impact. RE-AIM supported assessments of key partners at multiple organizational levels, capturing critical unit level outcomes. Multiple methods for data collection and analysis yielded rich results to inform future dissemination of MOVIN. [
Research in Gerontological Nursing, 17
(4), 189–201.]
Borderline lepromatous leprosy: A case report
Authors: Fernando Nilshan , Welhenge Chiranthi , Premaratna Ranjan , Uwyse Ahamed 
Published: July 2024

Rationale:
Lepromatous leprosy can have many atypical presentations, obscuring early diagnosis. We present a case of lepromatous leprosy, presenting with atypical features, which made a diagnostic dilemma.

Patient concerns:
A 48-year-old man presented with bilateral lower limb oedema and scaly “ichthyosis like” skin rash in both hands and feet, hepatosplenomegaly and pancytopenia, over a course of three months, without any classical features of leprosy. A skin biopsy revealed an unexpected diagnosis of borderline lepromatous leprosy.

Diagnosis:
Lepromatous leprosy.

Interventions:
Multi-drug regimen treatment with rifampicin, dapsone and clofazimine for lepromatous leprosy.

Outcomes:
The patient made a good clinical recovery.

Lessons:
In endemic settings, clinicians should be aware of similar atypical manifestations of leprosy to face the global challenge of eradicating this chronic deforming disease.
Effect of Educational Nursing Guidelines on Self-management and Health-Related Quality of Life for Hemodialysis Patients
Authors: Ibrahim Mona Hassan , Ali Amira Mohammed , Allawy Mohamed Elsayed Ahmed 
Published: July 2024

Abstract

Background:
Chronic kidney disease is the biggest problem in health care today, and the primary replacement therapy, hemodialysis, has a severe impact on both self-management and quality of life. This study aimed to evaluate the effect of educational nursing guidelines on self-management and health-related quality of life for hemodialysis patients.

Materials and Methods:
A quasi-experimental design was used. A convenience sample of 100 hemodialysis patients in the hemodialysis unit at Ismailia General Hospital, 50 patients for the study and 50 patients for the control groups. Data were collected using a patient demographic information questionnaire, hemodialysis self-management scale, and survey instrument on kidney disease quality of life 36-item (KDQOL-36). The intervention was conducted over 12 weeks in five sessions, from implementing the guidelines to the post-test phase. The control group received the usual care. SPSS version 23, descriptive statistics, and inferential statistics like independent t-test and Pearson Chi-square test were used.

Results:
Regarding self-management dimensions, a statistically significant difference was found between the study and control group regarding problem-solving and communications, fluid control, diet, self-advocacy, and emotional control with p < 0.001, and effect size 5.89,4.99, 5.06, and 4.54, respectively. Regarding the quality of life domains, a statistically significant difference was found between the study and control group regarding physical functioning, mental functioning, the burden of kidney disease, management of symptoms, and kidney disease effect with p < 0.001 and the effect size 9.39, 6.07, 1.86, 7.65, and 6.96, respectively.

Conclusions:
Educational guidelines are effective for improving self-management and quality of life.
The Effect of Music Therapy on the Sleep Quality of Patients with Heart Failure: The Miracle of Nature Music
Authors: Hosseini Nahid , Seylani Khatereh , Matourypour Pegah , Fakhrodini Mehrdad , Haghani Hamid , Zakerimoghadam Masoumeh 
Published: July 2024

Abstract

Background:
Patients with heart failure experience poor sleep quality due to the nature of disease they suffer from. The aim of this study was to investigate the effect of music on the sleep quality of patients with heart failure.

Materials and Methods:
The present study is a randomized clinical trial, which was performed on 76 patients with heart failure, hospitalized in the cardiac ward of an educational hospital. These patients had obtained a score of 5 or higher on Pittsburgh’s sleep quality index. The block randomization method was used to generate the allocation sequence. Thus, the number of subjects in each block was determined to be 4 people in 18 blocks. Intervention was collection of nature music played through headphones for 30 minutes over three nights, and at the end of the third night, the Pittsburgh’s index was completed again by both groups. Data were analyzed using descriptive and inferential statistics.

Results:
After the intervention, the mean scores of mental quality of sleep (p = 0.007) and daily function disorders improved significantly in the intervention group (p = 0.025). Significant differences were seen between the mean scores of mental quality of sleep (p < 0.001), daily function disorders (p = 0.002), delay in falling asleep (p = 0.01), sleep disorders (p < 0.001), and use of sleeping pills (p < 0.001) before and after the intervention in the intervention group.

Conclusions:
Playing relaxing music like nature sounds and spending time in nature after discharge can improve the sleep quality and sense of relaxation in patients with heart failure. The implementation of such affordable and amusing interventions can be proposed by nurses in heart failure patients.
Spirituality, a Neglected Dimension in Improving the Lifestyle of Coronary Artery Patients by Nurses: A Scoping Review
Authors: Abedini Fahimeh , Mokhtari Nouri Jamileh , Moradian Seyed Tayeb 
Published: July 2024

Abstract

Background:
By modifying the lifestyle of patients, the risk factors of Coronary Artery Diseases (CADs) are adjusted. This study was performed with the aim to investigate the role of nurses in the lifestyle of coronary artery patients.

Materials and Methods:
This scoping review was conducted with the question of the role of nurses in improving the lifestyle of coronary artery patients. This study was conducted in databases and search engines of ScienceDirect, Springer, Scopus, PubMed, MEDLINE, and Google Scholar for English texts, and in the Magiran and Scientific Information Database (SID) databases and search engines for the texts printed in Persian. The search for articles printed from 2012 to 2022 was conducted based on the keywords used in the title and abstract of the articles. The keywords used to search domestic databases included nursing, lifestyle and healthy lifestyle, and heart diseases (based on MeSH).

Results:
Nurses have made significant efforts and performed interventions to improve the lifestyle of coronary artery patients through guidance and education regarding the improvement of their diet and mobility, compliance with their treatment regimen, and reduction of the risk factors of CAD. In the psychological dimension, they had a positive effect in some fields such as stress management and mental health. However, in the spiritual dimension, effective studies and interventions have not been conducted by nurses.

Conclusions:
The role of nurses in the lifestyle of coronary artery patients is effective in the physical dimension, limited in the psychological dimension, and neglected in the spiritual dimension.
Comparative clinical experience of subcostal VATS versus conventional uniportal lateral VATS approach
Authors: Kösek Volkan , Al Masri Eyad , Nikolova Katina , Ellger Björn , Wais Shadi , Redwan Bassam 
Published: July 2024

Abstract

Introduction:
The present study reports the first clinical experience with subcostal uniportal VATS (suVATS) compared with the conventional lateral uniportal VATS (luVATS) approach.

Patients and Methods:
All patients who underwent suVATS between January 2019 and April 2020 were included. Patients who had undergone luVATS for similar indications were included as the control group. The data were prospectively and retrospectively analysed.

Results:
The suVATS group included 38 patients with a mean age of 61 (30–83) years. The luVATS group included 33 patients (mean age, 69 years; range: 46–89 years). An intercostal block was performed intraoperatively in the luVATS group. Local infiltration under anaesthesia was performed around the incision in the suVATS group. The duration of the surgery was significantly longer in the suVATS group. However, the chest tube treatment and hospital stay duration were significantly shorter in the suVATS group. The routinely recorded Visual Analogue Scale scores on the first post-operative day and the day of discharge were significantly lower in the suVATS group.

Conclusion:
Subcostal uniportal VATS enables a shorter drainage treatment duration and hospital stay and significantly reduces post-operative pain. Thus, a faster patient recovery can be achieved.
Gasless transoral endoscopic thyroidectomy in a primary substernal goitre patient: First case
Authors: Fang Jing , Wang Shengying , Liu Jianjun 
Published: July 2024

Abstract
For most primary substernal goitre (SG) surgeries, sternotomy is required because the blood supply vessels of tumours come from the mediastinum. However, sternal dehiscence may lead to several surgical complications. We reported an older patient who underwent simultaneous removal of a primary SG and parathyroid adenoma through a gasless transoral endoscopic approach. The patient recovered well with no hoarseness, post-operative bleeding or other complications after the operation. To the best of our knowledge, this is the first reported case of gasless transoral endoscopic parathyroid adenoma and primary SG resection in the real world. We found that gasless transoral endoscopic surgery is feasible in patients with small primary SG and parathyroid adenoma.
CD4+ Tumor-infiltrating Lymphocytes in Neoadjuvant Chemotherapy-treated Invasive Breast Cancer of No Special Type
Authors: Rustamadji Primariadewi , Wiyarta Elvan , Pramono Meike , Maulanisa Sinta Chaira 
Published: July 2024

Abstract

Background:
Neoadjuvant chemotherapy (NAC) is an integral component of modern treatment for invasive breast cancer with no special type (IBC-NST). The interaction between the immune system and cancer, particularly through immune-infiltrating lymphocytes (TIL), continues to be studied to understand how treatments like NAC influence the disease progression and response to various therapies. This study was designed to investigate changes in the pattern of CD4+ TIL infiltration before and after NAC.

Methods:
This retrospective cohort study involved 32 participants. NAC was administered for 3 months, comprising six cycles of chemotherapy. Variables such as age, tumor size, grade, lymphovascular invasion, and regional lymph node metastasis (RLNM) were evaluated. Furthermore, the expression of receptors, estrogen receptor, progesterone receptor, human epidermal growth factor receptor-2 (HER-2), and Ki-67 was evaluated. Infiltration of the tumor by CD4+ TILs was assessed using immunohistochemistry, whereas other data were retrieved from the medical records of the participants. Data were analyzed using R software.

Results:
There was a significant increase in CD4+ TIL infiltration after NAC administration. Before NAC treatment, there were significant associations between stromal CD4+ TIL with tumor size after NAC (P = 0.047), intratumoral CD4+ TIL with age (P = 0.031), and intratumoral CD4+ TIL with HER-2 status (P = 0.037). After NAC treatment, intratumoral CD4+ TIL was associated with tumor size before NAC (P = 0.009) and RLNM (P = 0.026).

Conclusion:
NAC is associated with a significant increase in CD4+ TIL infiltration in patients with IBC-NST.