bluuebunny/crossref_metadata_2025_split huggingface dataset:
Visual Inspection of Cervix with Acetic Acid as a Screening Test for Premalignant and Malignant Lesions of Cervix
Authors: Agarwal Shelly , Gupta Samta , Chutani Nimmi , Gulati SS 
Published: March 2015

ABSTRACT

Aims and objectives
To compare the efficacy of VIA and Pap smear for detection of premalignant and malignant lesions of cervix.

Materials and methods
Two hundred and forty women attending outpatient department of obstetrics and gynecology were subjected to detailed history taking, clinical examination, Pap smear and VIA, and biopsies were indicated.

Results
Of 240 patients, 27 patients (11.3%) were Pap positive and 28 patients (11.7%) were VIA positive. A total of 39 patients in whom either test was positive, had undergone cervical biopsy. Sensitivity of VIA and Pap smear was 92 and 84% respectively and specificity of VIA and Pap smear was 64.3 and 57% respectively.

Conclusion
The study concluded that sensitivity of VIA is comparable to Pap. Therefore, VIA is an efficacious and costeffective method to screen premalignant and malignant lesions of cervix, especially in developing countries like ours.

How to cite this article
Agarwal S, Gupta S, Chutani N, Gulati SS. Visual Inspection of Cervix with Acetic Acid as a Screening Test for Premalignant and Malignant Lesions of Cervix. J South Asian Feder Menopause Soc 2014;2(2):62-64.
Vaginal Reconstruction in Müllerian Agenesis with User- Friendly Indigenous Prosthetic Vaginal Dilators
Authors: LNU Pushpalatha , Syamala O , LNU Rukshana , Sangeetha K , Rani G Usha 
Published: March 2015

ABSTRACT

Objective
Vaginal reconstruction in Müllerian agenesis through nonsurgical method, using serial vaginal dilators which were worn by the patients with the help of a T-shaped perineal bandage.

Materials and methods
Seven patients with Müllerian agenesis had attended the outpatient clinic between 2008 and 2013. The age of women ranged from 18 to 30 years. This clinical report describes the use of prosthesis, fabricated by a maxillofacial prosthodontist that enabled the patients to have custom made personalized vaginal dilators of increasing dimensions which they could wear with comfort with a tight perineal T-bandage.

Results
Seven women with Müllerian agenesis had consented for nonsurgical mode of vaginal reconstruction. Vagina was serially dilated with tailor made prosthesis worn using tight perineal T-bandage for a period of 3 to 4 months. Post dilatation average vaginal length was 11 to 13 cm which allowed introduction of Sims speculum with ease.

Conclusion
Nonsurgical vaginal dilatation using prosthetic vaginal dilators kept in place with tight perineal T-bandage is a well-accepted custom made and a successful technique in the creation of neovagina.

How to cite this article
Sangeetha K, Rani GU, Syamala O, Rukshana, Pushpalatha. Vaginal Reconstruction in Müllerian Agenesis with User-Friendly Indigenous Prosthetic Vaginal Dilators. J South Asian Feder Menopause Soc 2014;2(2):75-78.
A Case of Stump Carcinoma with Incisional Site Metastasis
Authors: Sinha Mridu , Khandelwal Ruchee 
Published: March 2015

ABSTRACT
An abdominal wall incisional metastasis from an internal malignancy is rare. In developing countries, carcinoma cervix is the most common genital malignancy in women, cutaneous involvement is rare.

How to cite this article
Sinha M, Khandelwal R. A Case of Stump Carcinoma with Incisional Site Metastasis. J South Asian Feder Menopause Soc 2014;2(2):95-96.
A Rare Case Report of Microperforate Hymen with Difficulty in Penetration
Authors: Kumar Vijay , Kumar Kusuma Vijay , Krishnamurthy KH 
Published: March 2015

ABSTRACT
A rare case of 26-year-old women with microperforate hymen reported a difficulty in intercourse. Hymenectomy is the surgical treatment for imperforate hymen and microperforate hymen. A knife or electrocautery can be used to excise hymenal tissue.

How to cite this article
Kumar V, Kumar KV, Krishnamurthy KH, Kumar R. A Rare Case Report of Microperforate Hymen with Difficulty in Penetration. J South Asian Feder Menopause Soc 2014;2(2):97-98.
Adenomyosis in a Rudimentary Horn of a Mayer-Rokitansky-Küster-Hauser Syndrome
Authors: Rani G Usha , Syamala O , Meera A Dilshath , Rukshana HN 
Published: March 2015

ABSTRACT
The prevalence of congenital uterine malformations is about 0.5%. In Mayer-Rokitansky-Küster-Hauser syndrome (MRKH), patients usually present with primary amenorrhea. Here, we report a case of adenomyosis in a rudimentary horn in a 37-yearold woman with MRKH syndrome who had cyclical abdominal pain with increasing frequencies since her 24th year. This case is an evidence for adenomyotic lesions in the myometrium of Müllerian remnant with no functioning endometrium.

How to cite this article
Meera AD, Rani GU, Syamala O, Rukshana HN. Adenomyosis in a Rudimentary Horn of a Mayer-Rokitansky-Küster-Hauser Syndrome. J South Asian Feder Menopause Soc 2014;2(2):102-104.
Successful Uterovaginal Anastomosis in an Unusual Presentation of Congenital Absence of Cervix
Authors: Chowdhury TA , Mahmud Nusrat , Mahtab Naushaba Tarannum , Deb Anjan Kumar 
Published: March 2015

ABSTRACT
Cervical agenesis or dysgenesis (fragmentation, fibrous cord and obstruction) is an extremely rare congenital anomaly. Conservative surgical approach to these patients involves uterovaginal anastomosis, cervical canalization and cervical reconstruction. In failed conservative surgery, total hysterectomy is the treatment of choice. We report what we believe to be the first successful end-to-end uterovaginal anastomosis of an unusual case of congenital cervical agenesis. A 25-yearold female presented complaining of primary amenorrhea and primary subfertility for the same duration. At laparoscopy, complete separation between the cervix and the body of the uterus was found and hanging from surrounding supports. Both ovaries and fallopian tubes were anatomically positioned. There was another muscular tissue of 2 cm in diameter at the pouch of Douglas which was attached with lateral pelvic wall by transverse cervical ligament. Upon readmission, laparotomy was performed under general anesthesia in a semilithotomy position allowing both abdominal and vaginal approaches. Uterovaginal anastomosis was done by the restoration of the genital tract by direct suturing of the isthmus uteri to the vagina. Insertion of a 16F Foley catheter transvaginally through the vaginal opening into the endometrial cavity and was inflated with 5 ml of fluid into the catheter balloon. There were no postoperative complications. Foley catheter was kept in situ for 21 days. Patient had her first menstruation on 11th day of surgery and that was continued for 5 days with regular flow. Consecutive 3-cycles follow-up has been done and the patient is having her normal menstruation. In the presence of cervical anomaly with functional uterus and intact vagina, uterovaginal anastomosis is feasible and effective and should be applied as a first-line treatment option.

How to cite this article
Mahmud N, Mahtab NT, Chowdhury TA, Deb AK. Successful Uterovaginal Anastomosis in an Unusual Presentation of Congenital Absence of Cervix. J South Asian Feder Menopause Soc 2014;2(2):105-110.
Estudio del norte de Santiago de Chile mediante cartografía histórica:
Authors: Quilodrán Rubio Carolina , Sahady Villanueva Antonio , Bravo Sánchez José 
Published: March 2015

<p>En la ribera norte del río Mapocho, en Santiago de Chile, existió un área que fue<br />reconocida como La Chimba, el lugar ideal para que se asentaran allí numerosas familias<br />indígenas antes del periodo de fundación de la ciudad. Esta otra banda u otra orilla, –significado en lengua quechua de La Chimba–, durante largo tiempo fue el límite septentrional<br />de Santiago del Nuevo Extremo, con una historia y un desarrollo territorial marcados por<br />las diversas situaciones naturales y culturales de la ciudad. A partir de la documentación<br />histórica, en el presente estudio se analiza la representación de La Chimba entre los siglos<br />XVI y el XIX.</p>
The Perceived Value of Silence and Spoken Words in Malaysian Interactions
Authors: Hei Kuang Ching , Ling Wong Ngan , David Maya Khemlani 
Published: March 2015

Abstract
This paper analysed the perceptions of Malaysians in engaging silence (say nothing) and in using spoken words (talk) as a tool of communication in their daily interactions. Types of topics and situations being discussed were explored in order to detect when silence or words were likely to be used by participants. Self-administered questionnaires were distributed to students and staff of three public universities. Of the 656 samples collected, 50% were Chinese, 33% were Malays, 15% were Indians and 2% others. The demography consisted of 199 males and 456 females. SPSS version 18 was used to analyse data and results indicate that the use of silence was more significantly related to issues concerning money and personal affairs. In contrast, the use of spoken words was more significantly related to issues regarding infidelity. These findings are beneficial to researchers who are doing cross cultural studies and in particular, silence. Course designers can thus develop courses which can promote harmony by introducing certain strategies such as silence which, when used appropriately, can help to alleviate misunderstandings.
Olaparib Without Androgen Deprivation for High-Risk Biochemically Recurrent Prostate Cancer Following Prostatectomy
Authors: Marshall Catherine H. , Teply Benjamin A. , Lu Jiayun , Oliveira Lia , Wang Hao , Mao Shifeng S. , Kelly W. Kevin , Paller Channing J. , Markowski Mark C. , Denmeade Samuel R. , King Serina , Sullivan Rana , Davicioni Elai , Proudfoot James A. , Eisenberger Mario A. , Carducci Michael A. , Lotan Tamara L. , Antonarakis Emmanuel S. 
Published: August 2024

ImportanceOlaparib is a poly(adenosine diphosphate–ribose) polymerase inhibitor that provides benefit in combination with hormonal therapies in patients with metastatic prostate cancer who harbor homologous recombination repair (HRR) alterations. Its efficacy in the absence of androgen deprivation therapy has not been tested.ObjectiveTo determine the activity of olaparib monotherapy among patients with high-risk biochemically recurrent (BCR) prostate cancer after radical prostatectomy.Design, Setting, and ParticipantsThis phase 2, single-arm nonrandomized controlled trial enrolled genetically unselected patients across 4 sites in the US from May 2017 to November 2022. Eligible patients had BCR disease following radical prostatectomy, a prostate-specific antigen (PSA) doubling time of 6 months or shorter, an absolute PSA value of 1.0 ng/mL or higher, and a testosterone level of 150 ng/dL or higher.InterventionTreatment was with olaparib, 300 mg, by mouth twice daily until doubling of the baseline PSA, clinical or radiographic progression, or unacceptable toxic effects.Main Outcome and MeasureThe primary end point was a confirmed 50% or higher decline in PSA from baseline (PSA50). Key secondary end points were outcomes by HRR alteration status, as well as safety and tolerability.ResultsOf the 51 male patients enrolled (mean [SD] age, 63.8 [6.8] years), 13 participants (26%) had a PSA50 response, all within the HRR-positive group (13 of 27 participants [48%]). All 11 participants with BRCA2 alterations experienced a PSA50 response. Common adverse events were fatigue in 32 participants (63%), nausea in 28 (55%), and leukopenia in 22 (43%), and were consistent with known adverse effects of olaparib.Conclusions and RelevanceIn this nonrandomized controlled trial, olaparib monotherapy led to high and durable PSA50 response rates in patients with BRCA2 alterations. Olaparib warrants further study as a treatment strategy for some patients with BCR prostate cancer but does not have sufficient activity in those without HRR alterations and should not be considered for those patients.Trial RegistrationClinicalTrials.gov Identifier: NCT03047135
Oxygen Ion Pumping across Atomically Designed Oxide Heterointerfaces
Authors: Wu Yongshun , Zhang Yang , Zhang Jianbing , Lyu Yingjie , Li Cong , Wu Sijie , Wang Yupu , Wang Meng , Long Youwen , Nan Tianxiang , Yi Di , Zhu Junyi , He Qing , Zhou Shuyun , Yu Pu 
Published: August 2024

AbstractComplex oxide heterointerfaces and heterostructures have demonstrated enormous emergent phenomena over the last decades, attributed to the reconstructions of mis‐matched crystalline structure, polarity, and spin ordering across the heterointerfaces. This work employs the heterostructures of La0.7Sr0.3MnO3 and CaFeO2.5 as model system to demonstrate an interface‐specific oxygen migration/reconstruction across the interfaces due to the mismatched chemical potential, which dramatically influences the ferromagnetic and electronic states of La0.7Sr0.3MnO3 layer. Specifically, the alternative stacking of octahedral (Oh) and tetrahedral (Td) layers in CaFeO2.5 are used to form two distinct heterointerfaces, namely the Oh‐Td and the Oh‐Oh interfaces with the adjacent La0.7Sr0.3MnO3 layer. Interestingly, the oxygen ion migrates toward opposite directions across the interface for these two cases, in which the CaFeO2.5 layer acts as an “oxygen pump” and manipulates the oxygen contents of its adjacent La0.7Sr0.3MnO3 layers. Such manipulation leads to a dramatically changed ferromagnetic transition temperature for the heterostructure with the Oh‐Td and Oh‐Oh interface. This work establishes a feasible and efficient strategy to control the oxygen ionic distribution through atomic‐scale interface design and opens up new opportunities to exploit emergent states at the complex oxide heterostructures through selective oxygen ion evolution.
Hierarchically Porous and Hetero‐Structured Black Phosphorus/Ti3C2TX MXene Aerogel Fiber for Wearable Supercapacitors with Implantable Capability
Authors: Tang Qingqing , Zhang Yang , Zhu Xiaolin , Wang Yuting , Man Zengming , Yang Chao , Xu Jianhong , Wu Guan , Lu Wangyang 
Published: August 2024

AbstractArchitected fibrous electrodes with hierarchically porous, stable interface coupling, and good biocompatibility that accelerates charge transfer and storage are vital to realize high‐performance fiber‐shaped supercapacitors (FSCs) toward wearable and implantable systems. Here, a hierarchically porous and hetero‐structured black phosphorus/Ti3C2TX MXene aerogel (A‐BP/Ti3C2TX) fiber based on electrostatic self‐assembly and microfluidic spinning methods is reported. The as‐prepared A‐BP/Ti3C2TX fiber with interconnected porous networks, high conductive skeleton, and substantial interfacial building exhibits a low diffusion energy barrier of H+, the large adsorption energy of H+, fast interfacial electron conduction, and excellent structural stability by density functional theory calculations and in situ/ex situ characteristics. As a result, the A‐BP/Ti3C2TX fiber presents boosted electrolyte ion diffusion kinetic and capacitance of 369 F g−1. Furthermore, the asymmetric FSCs deliver good energy density of 6.39 Wh kg−1 and long cycling stability of 20 000 cycles, thereby successfully powering wearable devices. More importantly, by combining the hydrogel adhesion agent, the implantable FSCs that can firmly adhere to the tissues show significant bending stability (88.52% capacitance retention after 5000 cycles), impressively adhesive capability in tissue fluid or wetted tissue surface, and considerably no cell toxic. The work offers a broad path for designing structural fiber electrodes for implantable energy technology and wearable applications.
Heterostructured Metallic Structural Materials: Research Methods, Properties, and Future Perspectives
Authors: Dong Xinxin , Gao Bo , Xiao Lirong , Hu Jiajun , Xu Mengning , Li Zongyao , Meng Jiaqi , Han Xiaodong , Zhou Hao , Zhu Yuntian 
Published: August 2024

AbstractHeterostructured (HS) materials, characterized by heterogeneous zones with differences in mechanical or physical properties, represent a revolutionary advancement in material science. During deformation, hetero‐deformation‐induced (HDI) stress forms due to the synergistic interactions between soft and hard zones, leading to remarkable HDI strengthening and strain hardening. This mechanism significantly enhances their performance, surpassing that of traditional homogeneous materials. This review delves into the classification, preparation techniques, fundamental deformation mechanisms, and research methods of HS materials. It outlines the preparation methods of various HS materials, emphasizing their unique characteristics and applications. The review elaborates on the fundamental deformation mechanisms of HS materials, focusing on non‐uniform plastic deformation behavior and HDI strain hardening. Furthermore, it explores the application of heterogeneous design concepts in materials, analyzing their microstructure tuning mechanisms and mechanical properties. This review aims to serve as a critical reference for the future design and development of new HS metallic structural materials, paving the way for innovations that can transform multiple industries. By highlighting the long‐term impact, this review not only enhances the understanding of HS materials but also provides a roadmap for future research and industrial applications, positioning HS materials as key players in the advancement of material technology.
Design of Metal Aerogels‐Based 3D SERS Substrates by Gentle Compression
Authors: Zhou Lin , Liu Yu , Li Yanli , Long Chunlei , Zhou Shujin , Hübner René , Li Yueqi , Xue Geng , Lin Dejun , Xu Weigao , Hu Yue , Du Ran 
Published: August 2024

AbstractMetal aerogels (MAs) are emerging all‐nanometal‐structured self‐standing porous materials featuring exceptional performances in diverse fields. They have recently been adopted as 3D surface‐enhanced Raman scattering (SERS) substrates, while the less utilization of the unique porous structure leads to limited performance. Here, a fascinating compression‐mediated regulation strategy is presented to largely boost the SERS performance of Au–Ag aerogels. By gently pressing, both the density of hot spots and the inter‐ligament distance can be efficiently modulated, thus enabling to flexibly manipulate the SERS properties of MAs. On this basis, a record‐high misfocus tolerance (∼8.8 mm), low detection limit (down to 0.1 nM), high stability (>1 month), reusability, and multiplex detection ability are concurrently realized. This study may point out a new direction for engineering 3D SERS substrates with tunable and exceptional performance.
Stimuli‐Responsive NO Delivery Platforms for Bacterial Infection Treatment
Authors: Hu Yanling , Ding Meng , Lv Xinyi , Jiang Jingai , Zhang Junjie , Yang Dongliang 
Published: August 2024

AbstractThe prevalence of drug‐resistant bacterial infections has emerged as a grave threat to clinical treatment and global human health, presenting one of the foremost challenges in medical care. Thus, there is an urgent imperative to develop safe and efficacious novel antimicrobial strategies. Nitric oxide (NO) is a recognized endogenous signaling molecule, which plays a pivotal role in numerous pathological processes. Currently, NO has garnered significant interest as an antibacterial agent due to its capability to eradicate bacteria, disrupt biofilms, and facilitate wound healing, all while circumventing the emergence of drug resistance. However, the inherently unstable characteristic of NO therapeutic gas renders the controlled administration of NO gases exceedingly challenging. Hence, in this review, the current challenge of bacterial infection is discussed; then it is briefly elucidated the antibacterial mechanism of NO and comprehensively delineate the recent advancements in stimulus‐responsive NO delivery platforms, along with their merits, obstacles, and prospective avenues for clinical application. This review offers guidance for future advancements in NO‐medicated anti‐infection therapy is hoped.
Trap‐Controlled, Recoverable, and Persistent Mechanoluminescence for Collision Early‐Warning and Mechanics Displaying Applications
Authors: Ma Zhidong , Fang Shaofan , Zhou Bo , Yan Chunmei , Wang Zhaofeng 
Published: August 2024

AbstractThe structural nondestructive, recoverable, and persistent mechanoluminescence (ML) is particularly required for mechanics‐driven displaying, imaging, and visualization applications. Inspired by the luminescent physics of the long afterglow materials, this work reports the ML of SrMg2(PO4)2:Eu2+ by incorporating the powders into a flexible polydimethylsiloxane (PDMS). The results suggest that the ML from the SrMg2(PO4)2:Eu2+/PDMS is recoverable with a linear responsiveness to the applied stress/strain. Moreover, the SrMg2(PO4)2:Eu2+/PDMS exhibits ML afterglow (persistent ML), which could continuously emit luminescence after removing the mechanics stimulus source. The discussions from the matrix effects, the trap structure evolutions, and the piezoelectricity properties suggest that the piezoelectric field‐assisted trap‐controlled processes shall be responsible for the ML and the persistent ML, which can be further improved by co‐doping Ho3+. Based on the recoverable and persistent ML, two types of attractive applications in terms of the intelligent collision early‐warning system and the flexible displaying paper are developed, respectively. This work not only achieves the recoverable and persistent ML for representative applications, but also provides deep insight into the physical process, which should be valuable to guide future research.
Various Applications of Gadolinium Molybdate Down‐Conversion and Up‐Conversion Fluorescent Nanoparticles
Authors: Jung Jae Yong , Park Jin Young , Yang Hyun Kyoung 
Published: August 2024

AbstractCrystalline α‐Gd2(MoO4)3 is synthesized by sintering at 800 °C using a coprecipitation method to prepare the precursor. The resulting α‐Gd2(MoO4)3 displayed a monocrystalline structure with a strong main peak (‐221) in the X‐ray diffraction signal. To develop a light‐emitting material, rare earth ions are added during synthesis. By doping with Tb3+ and Eu3+, the Gd2(MoO4)3 down‐conversion phosphor shows potential for use in UV–LED chips, counterfeit money prevention, and fingerprint identification. Additionally, co‐doping with [Er3+]/[Yb3+] and [Ho3+]/[Yb3+] ions produce green and red emissions when applied to a 980 nm LED chip, useful for anti‐counterfeit ink. The magnetic properties of gadolinium are leveraged to confirm magnetic resonance imaging luminescence. A flexible composite for heat detection and explored various applications for its use is also developed.
Optically Isotropic Polymer Stabilized Liquid Crystals with Fast and Large Field‐Induced Refractive Index Variation
Authors: Talwar Manisha , Perera Kelum , Mostafa Md , Gill Minakshi , Nepal Pawan , Guragain Parikshit , Landau Igor , Kula Przemysław , Twieg Robert , West John L. , Jákli Antal 
Published: August 2024

AbstractOptically isotropic polymer stabilized liquid crystals with low haze (≈1% at 550 nm), large (≈0.09) field induced refractive index variation, and fast (<0.1 ms) relaxation time are reported. The impressive improvement compared to previous studies using conventional nematic liquid crystals are due to both the addition of novel highly polar ferroelectric nematic liquid crystals that decrease the required field to achieve the theoretically predicted refractive index variation and of the 6 wt.% of chiral dopant with high helical twisting power that suppressed the haze and made the system reversible with fast relaxation. It is also shown that the field induced refractive index variation can be increased over to 0.1 by using high intensity UV light for polymer stabilization. Although such polymer structure is not completely isotropic, it still provides polarization independent optical properties for normal incidence. Since fast and large switching of focal length is essential in AR/VR glasses, these systems offer significant potential for applications in highly tunable microlens arrays.