bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reconstruction of historical noise exposure data for environmental epidemiology in Switzerland within the SiRENE project
Authors: Karipidis Ioannis , Vienneau Danielle , Habermacher Manuel , Köpflii Micha , Brink Mark , Probst-Hensch Nicole , Röösli Martin , Wunderli Jean-Marc 
Published: August 2014

AbstractIn 2014 the three-year interdisciplinary study SiRENE (Short and Long Term Effects of Traffic Noise Exposure) was launched in Switzerland. The goal of SiRENE is to investigate acute, short- and long-term e_ects of road, railway and aircraft noise exposure on annoyance, sleep disturbances and cardio-metabolic risk.The study is based on a detailed Swiss-wide assessment of transportation noise exposure, including diurnal distributions. The exposure analysis comprises current as well as historical exposure calculations for up to 20 years in the past.We present the major challenges of compiling sufficient data to support a Swiss-wide model for all buildings and including all transport infrastructure as a basis for the subsequent SiRENE sound exposure analysis for the years 2011, 2001 and 1991. The task is particularly challenging for the early years due to poor data quality and/or lack of availability. We address the integration of geo-referenced input datasets from various sources and time periods, the assignment of tra_c noise exposure from façade points to dwelling units, as well as the processing of traffic information and statistics. Preliminary results of the noise exposure calculations are presented.
Usefulness of Composite Restoration in Direct Esthetic Closure of Midline Gap
Authors: Chałas Renata , Orłowski Mirosław , Sękowska Anna 
Published: August 2014

Abstract

Introduction. Midline gap (diastema) is a space between two teeth, commonly between two incisors. The treatment can be provided by orthodontic, conservative (restorative) or prosthetic methods.

Aim. The aim of the study was an assessment of using direct composite restoration in aesthetic closing of diastema.

Material and methods. The space correction between teeth was performed among female and male adult patients with diastema of 3 to 6 mm. The microhybrid resin composite was used for the composite build-ups with a help of celluloid or silicon matrix due to its good handling properties and shade matching, and polishability properties.

Results. Depending on the size of diastema, the partial or total closing was done to achieve the cosmetic effect. The obtained clinical results were highly assessed both by dentists and patients. It was possible to obtain optimal aesthetic results with resin composite restorations only.

Conclusions. The simple closure of diastema with direct composite reconstructions can result in successful outcome and patient's satisfaction.
Multidimensional Risk Management for Underground Electricity Networks
Authors: Garcez Thalles V. , Szufel Przemyslaw 
Published: August 2014

Abstract
In the paper we consider an electricity provider company that makes decision on allocating resources on electric network maintenance. The investments decrease malfunction rate of network nodes. An accidental event (explosion, fire, etc.) or a malfunctioning on underground system can have various consequences and in different perspectives, such as deaths and injuries of pedestrians, fires in nearby locations, disturbances in the flow of vehicular traffic, loss to the company image, operating and financial losses, etc. For this reason it is necessary to apply an approach of the risk management that considers the multidimensional view of the consequences. Furthermore an analysis of decision making should consider network dependencies between the nodes of the electricity distribution system. In the paper we propose the use of the simulation to assess the network effects (such as the increase of the probability of other accidental event and the occurrence of blackouts of the dependent nodes) in the multidimensional risk assessment in electricity grid. The analyzed effects include node overloading due to malfunction of adjacent nodes and blackouts that take place where there is temporarily no path in the grid between the power plant and a node. The simulation results show that network effects have crucial role for decisions in the network maintenance – outcomes of decisions to repair a particular node in the network can have significant influence on performance of other nodes. However, those dependencies are non-linear. The effects of network connectivity (number of connections between nodes) on its multidimensional performance assessment depend heavily on the overloading effect level. The simulation results do not depend on network type structure (random or small world) – however simulation outcomes for random networks have shown higher variance compared to small-world networks.
The Occurrence of the Day-of-the-Week Effects on Polish and Major World Stock Markets
Authors: Jamróz Paweł , Koronkiewicz Grzegorz 
Published: August 2014

Abstract
The aim of this paper is to analyze the occurrence of the so called day of the week effects in market return time series from the period of January 2003 to September 2013 (and additionally January 1999 to December 2002). The study focuses on four indices of the Warsaw Stock Exchange (WIG, WIG20, mWIG40 and sWIG80) and additionally five indices of major world stock exchanges (NIKKEI 225, DAX, CAC40, S&P 500, and IBEX). The main data sample was divided into three subperiods in order to determine whether or not the intensity of day of the week anomalies is constant in time. The study revealed a substantial number of the day of the week anomalies in earliest subperiods and very limited evidence of those effects in later ones, giving rise to the conclusion that the intensity of the day of the week anomalies is diminishing with time. The most common effect identified on the WSE was a positive Friday effect. The Monday effect often described in early literature on the subject matter seems to currently occur very rarely. The study also indicates that the day of the week effects were more persistent among stocks with smaller market capitalization on the WSE.
Decision Support System for Blockage Management in Fire Service
Authors: Krasuski Adam , Kreński Karol 
Published: August 2014

Abstract
In this article we present the foundations of a decision support system for blockage management in Fire Service. Blockage refers to the situation when all fire units are out and a new incident occurs. The approach is based on two phases: off-line data preparation and online blockage estimation. The off-line phase consists of methods from data mining and natural language processing and results in semantically coherent information granules. The online phase is about building the probabilistic models that estimate the block-age probability based on these granules. Finally, the selected classifier judges whether a blockage can occur and whether the resources from neighbour fire stations should be asked for assistance.
Environmental Quality as a Decisive Variable in Shaping Regional Development Policy
Authors: Perło Dorota 
Published: August 2014

Abstract
The article examines the impact of environmental quality on shaping the development policy of Polish voivodeships. The main analytical tool used was the synthetic index of environmental quality, compiled by means of the Perkal method. It was constructed in order to organize Polish voivodeships in terms of environmental quality, which was determined in a comprehensive way on the basis of three thematic areas: advantages of the natural environment, the level of pollution (degradation) of the environment as well as active protective activities. The obtained values of synthetic measures were then compared to the level of economic growth of Polish regions. It was necessary in determining which voivodeships perceive the quality of the environment as the main factor enhancing their economic growth, and which treat it as a barrier to economic development.
On Imprecise Investment Recommendations
Authors: Piasecki Krzysztof 
Published: August 2014

Abstract
The return rate is considered here as a fuzzy probabilistic set. Then the expected return is obtained as a fuzzy subset in the real line. This result is a theoretical foundation for new investment strategies. All considered strategies result of comparison profit fuzzy index and limit value. In this way we obtain an imprecise investment recommendation. Financial equilibrium criteria are a special case of comparison of the profit index and the limit value. The following criteria are generalized here: the Sharpe's Ratio, the Jensen's Alpha and the Treynor's Ratio. Moreover, the safety-first criteria are generalized here for the fuzzy case. The Roy Criterion, the Kataoka Criterion and the Telser Criterion are also generalized. Obtained results show that proposed theory is useful for the investment applications.
Assorted Methods of Making of Pricing Decisions in an Enterprise
Authors: Wnorowski Henryk 
Published: August 2014

Abstract
Decisions concerning price development are best visible in view of their direct impact on the market activities of the company and the general level of profitability. In every activity, the success is measured by an excess of sales revenue over the costs of used resources. In an ideal case, a determined price provides the highest margin resulting from an analysis of the sales volume, takes into consideration the customer's evaluation of the product/service, and allows to react to competitive threats and to fend off the competition's attacks. There is no single universal way to develop prices for various enterprise types, regardless of the conditions of demand, the specific character of the sector they operate in, or the competitive situation, even if we assume that the enterprise has only one goal of activity. That's why, Author recommends three price determination methods. The ways of price determination presented in this article are just the first step on the way to reach the optimal prices. The prices determined in such way, as well as product or service prices already functioning in the market, are subject to modification depending on the assumed goals, taking into consideration the character of demand for a given commodity and the behaviour of the competition.
Using Additive Main Effect and Multiplicative Interaction Model for Exploration of Yield Stability in Some Lentil (Lens Culinaris Medik.) Genotypes
Authors: Sabaghnia Naser , Karimizadeh Rahmatollah , Mohammadi Mohtasham 
Published: August 2014

AbstractThe additive main effect and multiplicative interaction (AMMI) analysis has been indicated to be effective in interpreting complex genotype by environment (GE) interactions of lentil (Lens culinarisMedik.) multienvironmental trials. Eighteen improved lentil genotypes were grown in 12 semiarid environments in Iran from 2007 to 2009. Complex GE interactions are difficult to understand with ordinary analysis of variance (ANOVA) or conventional stability methods. Combined analysis of variance indicated the genotype by location interaction (GL) and three way interactions (GYL) were highly significant. FGH1and FGH2tests indicated the five significant components; FRatioshowed three significant components and F-Gollob detected seven significant components. The RMSPD (root mean square predicted difference) values of validation procedure indicated seven significant components. Using five components in AMMI stability parameters (EVFI, SIP-CFI, AMGEFI and DFI) indicated that genotypes G5 and G6 were the most stable genotypes while considering three components in of AMMI stability parameters (EVFII, SIPCFII, AMGEFII and DFII) showed that genotypes G8 and G18 were the most stable genotypes. Also genotypes G2, G5 and G18 were the most stable genotypes according to AMMI stability parameters which calculated from seven components (EVFIII, SIP-CFIII, AMGEFIII and DFIII). Among these stable genotypes, only genotypes G2 (1365.63 kg × ha-1), G11 (1374.13 kg × ha′1) and G12 (1334.73 kg × ha-1) had high mean yield and so could be regarded as the most favorable genotype. These genotypes are therefore recommended for release as commercial cultivars.
A protocol for the creation of useful geometric shape metrics illustrated with a newly derived geometric measure of leaf circularity
Authors: Krieger Jonathan D. 
Published: August 2014

• Premise of the study: I present a protocol for creating geometric leaf shape metrics to facilitate widespread application of geometric morphometric methods to leaf shape measurement.• Methods and Results: To quantify circularity, I created a novel shape metric in the form of the vector between a circle and a line, termed geometric circularity. Using leaves from 17 fern taxa, I performed a coordinate‐point eigenshape analysis to empirically identify patterns of shape covariation. I then compared the geometric circularity metric to the empirically derived shape space and the standard metric, circularity shape factor.• Conclusions: The geometric circularity metric was consistent with empirical patterns of shape covariation and appeared more biologically meaningful than the standard approach, the circularity shape factor. The protocol described here has the potential to make geometric morphometrics more accessible to plant biologists by generalizing the approach to developing synthetic shape metrics based on classic, qualitative shape descriptors.
Âge, absence-maladie et présentéisme au travail : le cas d'un établissement de santé régional
Authors: Huver Benjamin , Richard Sébastien , Vaneecloo Nicolas , Bierla Ingrid 
Published: August 2014

Notre article explore le lien entre l’âge et deux évènements de la vie au travail : l’absence-maladie de courte durée et le présentéisme. Ce dernier caractérise la situation d’un salarié se rendant à son travail, alors que son état de santé justifierait une absence. Pour cela, nous étudions le cas d’un centre hospitalier régional employant environ 4 000 salariés. La technique statistique utilisée repose sur l’hypothèse que les valeurs nulles d’absence (aucune absence enregistrée) peuvent s’expliquer soit par une bonne santé, soit par le présentéisme. Sur la base d’un modèle de comptage permettant un traitement différencié de ces deux processus (un modèle binomial négatif à inflation de zéros), nous estimons conjointement une espérance d’absence et une probabilité de présentéisme pour chaque individu. Cette méthode économétrique est ensuite appliquée à une analyse en catégories d’âge. Nos résultats montrent que deux effets jouent parallèlement et s’annulent en apparence dans une analyse statistique générale. D’une part, on s’aperçoit que pour les individus appartenant aux classes d’âge supérieures, la durée moyenne de l’absence est plus importante que pour les autres, comme le montre la littérature. Lorsqu’ils s’absentent, les salariés séniors connaissent des périodes d’absence plus longues, pouvant s’expliquer par un état de santé plus fragile et une guérison plus lente. D’autre part, ces salariés sont aussi ceux dont les probabilités de présentéisme sont les plus élevées. Ainsi, les séniors sont-ils également davantage présents au travail lorsqu’ils sont malades.
Prevention of Neutrophil Extravasation by α2-Adrenoceptor–Mediated Endothelial Stabilization
Authors: Herrera-García Ada María , Domínguez-Luis María Jesús , Arce-Franco María , Armas-González Estefanía , Álvarez de La Rosa Diego , Machado José David , Pec Martina K. , Feria Manuel , Barreiro Olga , Sánchez-Madrid Francisco , Díaz-González Federico 
Published: August 2014

Abstract
Adrenergic receptors are expressed on the surface of inflammation-mediating cells, but their potential role in the regulation of the inflammatory response is still poorly understood. The objectives of this work were to study the effects of α2-adrenergic agonists on the inflammatory response in vivo and to determine their mechanism of action. In two mouse models of inflammation, zymosan air pouch and thioglycolate-induced peritonitis models, the i.m. treatment with xylazine or UK14304, two α2-adrenergic agonists, reduced neutrophil migration by 60%. The α2-adrenergic antagonist RX821002 abrogated this effect. In flow cytometry experiments, the basal surface expression of L-selectin and CD11b was modified neither in murine nor in human neutrophils upon α2-agonist treatment. Similar experiments in HUVEC showed that UK14304 prevented the activation-dependent upregulation of ICAM-1. In contrast, UK14304 augmented electrical resistance and reduced macromolecular transport through a confluent HUVEC monolayer. In flow chamber experiments, under postcapillary venule-like flow conditions, the pretreatment of HUVECs, but not neutrophils, with α2-agonists decreased transendothelial migration, without affecting neutrophil rolling. Interestingly, α2-agonists prevented the TNF-α–mediated decrease in expression of the adherens junctional molecules, VE-cadherin, β-catenin, and plakoglobin, and reduced the ICAM-1–mediated phosphorylation of VE-cadherin by immunofluorescence and confocal analysis and Western blot analysis, respectively. These findings indicate that α2-adrenoceptors trigger signals that protect the integrity of endothelial adherens junctions during the inflammatory response, thus pointing at the vascular endothelium as a therapeutic target for the management of inflammatory processes in humans.
Dynamic Change in Cells Expressing IL-1β in Rat Hippocampus after Status Epilepticus
Authors: Sakuma Satoru , Tokuhara Daisuke , Otsubo Hiroshi , Yamano Tsunekazu , Shintaku Haruo 
Published: August 2014

Background The time course of cytokine dynamics after seizure remains controversial. Here we evaluated the changes in the levels and sites of interleukin (IL)-1β expression over time in the hippocampus after seizure. Methods Status epilepticus (SE) was induced in adult Wistar rats by means of intraperitoneal injection of kainic acid (KA). Subsequently, the time courses of cellular localization and IL-1β concentration in the hippocampus were evaluated by means of immunohistochemical and quantitative assays. Results On day 1 after SE, CA3 pyramidal cells showed degeneration and increased IL-1β expression. In the chronic phase (>7 days after SE), glial fibrillary acidic protein (GFAP)–-positive reactive astrocytes–-appeared in CA1 and became IL-1β immunoreactive. Their IL-1β immunoreactivity increased in proportion to the progressive hypertrophy of astrocytes that led to gliosis. Quantitative analysis showed that hippocampal IL-1β concentration progressively increased during the acute and chronic phases. Conclusion IL-1β affects the hippocampus after SE. In the acute phase, the main cells expressing IL-1β were CA3 pyramidal cells. In the chronic phase, the main cells expressing IL-1β were reactive astrocytes in CA1.
Evaluating a federated medical search engine
Authors: Belden J. , Williams J. , Richardson B. , Schuster K. , Saparova D. 
Published: August 2014

SummaryBackground: Federated medical search engines are health information systems that provide a single access point to different types of information. Their efficiency as clinical decision support tools has been demonstrated through numerous evaluations. Despite their rigor, very few of these studies report holistic evaluations of medical search engines and even fewer base their evaluations on existing evaluation frameworks.Objectives: To evaluate a federated medical search engine, MedSocket, for its potential net benefits in an established clinical setting.Methods: This study applied the Human, Organization, and Technology (HOT-fit) evaluation framework in order to evaluate MedSocket. The hierarchical structure of the HOT-factors allowed for identification of a combination of efficiency metrics. Human fit was evaluated through user satisfaction and patterns of system use; technology fit was evaluated through the measurements of time-on-task and the accuracy of the found answers; and organization fit was evaluated from the perspective of system fit to the existing organizational structure.Results: Evaluations produced mixed results and suggested several opportunities for system improvement. On average, participants were satisfied with MedSocket searches and confident in the accuracy of retrieved answers. However, MedSocket did not meet participants’ expectations in terms of download speed, access to information, and relevance of the search results. These mixed results made it necessary to conclude that in the case of MedSocket, technology fit had a significant influence on the human and organization fit. Hence, improving technological capabilities of the system is critical before its net benefits can become noticeable.Conclusions: The HOT-fit evaluation framework was instrumental in tailoring the methodology for conducting a comprehensive evaluation of the search engine. Such multidimensional evaluation of the search engine resulted in recommendations for system improvement.Citation: Saparova D, Belden J, Williams J, Richardson B, Schuster K. Evaluating a federated medical search engine: Tailoring the methodology and reporting the evaluation outcomes. Appl Clin Inf 2014; 5: 731–745http://dx.doi.org/10.4338/ACI-2014-03-RA-0021
Hermansky-Pudlak syndrome
Authors: Sánchez-Guiu I. , Torregrosa J. M. , Velasco F. , Antón A. I. , Lozano M. L. , Vicente V. , Rivera J. 
Published: August 2014

SummaryHermansky-Pudlak syndrome (HPS) is a rare, autosomal recessive disorder affecting lysosome-related organelles (LRO), including dense platelet granules. HPS causes oculo- cutaneous hypopigmentation, bleeding diathesis and granulomatous colitis or pulmonary fibrosis. To date, there is no curative treatment and the clinical management depends on the severity of symptoms. A prompt diagnosis of HPS patients could improve their quality of life and clinical management. However, the absence of a specific platelet function test, the wide molecular heterogeneity, and the lack of phenotypegenotype correlations hamper the rapid diagnosis. Nine subtypes of HPS have been identified as a result of mutations in nine genes that codify for proteins involved in formation and shuttle of the LRO. The molecular characterization of patients and knowledge derived from animal models of HPS contribute to the understanding of biogenesis and function of the LRO.This paper describes a patient with a novel homozygous nonsense mutation causing HPS and provides a review of the literature focusing on recent advances in the molecular characterization and physiopathology of HPS.
Fault accommodation for multi‐input linear sampled‐data systems
Authors: Cristofaro Andrea , Pettinari Silvia 
Published: August 2014

SummaryA novel observer‐based fault accommodation technique for linear multi‐input multi‐output sampled‐data systems affected by a general class of actuator faults in the presence of quantization errors is addressed in the paper. Only the output signal has been assumed to be available for direct measurement. A simulation study on a three‐tank system supports theoretical developments. Copyright © 2014 John Wiley & Sons, Ltd.
Decarboxylative CP Coupling of o‐Nitrobenzoic Acids with H‐Phosphonates
Authors: Li Junchen , Bi Xiaojing , Wang Hongmei , Xiao Junhua 
Published: August 2014

AbstractWe describe a decarboxylative CP coupling of o‐nitrobenzoic acids with H‐phosphonates by using a bimetallic palladium/silver catalytic system. Many common functional groups on the phenyl ring of o‐nitrobenzoic acids, such as MeO, NO2, F, Cl, and Br, are well tolerated under these conditions. Nevertheless, m‐ or p‐substituted benzoic acids are inert for the reaction. This transformation provides an approach to biologically and synthetically important aryl phosphonates.