bluuebunny/crossref_metadata_2025_split huggingface dataset:
Formation of the Jurassic Changboshan‐Xieniqishan highly fractionated I‐type granites, northeastern China: implication for the partial melting of juvenile crust induced by asthenospheric mantle upwelling
Authors: Zhang Daohan , Wei Junhao , Fu Lebing , Chen Huayong , Tan Jun , Li Yanjun , Shi Wenjie , Tian Ning 
Published: October 2013

AbstractZircon U–Pb ages, major and trace elements, and Sr, Nd and Hf isotope compositions of the Changboshan‐Xieniqishan (CX) intrusion from the Great Xing'an Range (GXAR), northeastern China, were studied to investigate its derivation, evolution and geodynamic significance. Laser ablation inductively coupled plasma mass spectrometry (LA‐ICP‐MS) zircon U–Pb dating yields an emplacement age of 161 ± 2 Ma for the CX intrusion. Bulk‐rock analyses show that this intrusion is characterized by high SiO2, Na2O and K2O, but low MgO, CaO and P2O5. They are enriched in large‐ion lithophile elements and light rare earth elements, with marked Eu anomalies (mostly from 0.36 to 0.65), and depleted in heavy rare earth elements and high field strength elements. Most samples have relatively low (87Sr/86Sr)i values (0.70423–0.70457), with εNd(t) fluctuating between −0.4 and 2.3. The εHf(t) for zircons varies from 5.4 to 8.7. Sr–Nd isotope modelling results, in combination with young Nd and Hf model ages (760–986 and 549–728 Ma, respectively) and the presence of relict zircons, indicate that the CX intrusion may originate from the partial melting of juvenile crust, with minor contamination of recycled crustal components, and then underwent extensive fractional crystallization of K‐feldspar, plagioclase, biotite, sphene, apatite, zircon and allanite. Considering the widespread presence of granitoids with coeval volcanic rocks, we contend that the CX intrusion formed in an extensional environment related to the upwelling of asthenospheric mantle induced by the subduction of the Palaeo‐Pacific plate, rather than a lithospheric delamination model. Copyright © 2013 John Wiley & Sons, Ltd.
RELATION BETWEEN SOCIAL WITHDRAWAL SYMPTOMS IN FULL‐TERM AND PREMATURE INFANTS AND DEPRESSIVE SYMTOMS IN MOTHERS: A LONGITUDINAL STUDY
Authors: Braarud Hanne C. , Slinning Kari , Moe Vibeke , Smith Lars , Vannebo Unni Tranaas , Guedeney Antoine , Heimann Mikael 
Published: October 2013

ABSTRACTThe objective of this longitudinal study was to investigate the prevalence of infants' social withdrawal and mothers’ depressive symptoms in a cohort of full‐term infants and their mothers and in a cohort of moderately premature infants and their mothers at 3, 6, and 9 months’ postpartum. The Alarm Distress Baby Scale (ADBB) was used to assess social withdrawal; the Edinburgh Postnatal Depression Scale (EPDS) was administered to ascertain postpartum depressive symptoms. The results revealed a higher proportion of premature infants with social withdrawal at 6 months’ postpartum and significantly higher ADBB composite scores at 3 and 6 months of age, as compared with the full‐term infants. A higher proportion of mothers in the premature cohort had symptoms of postpartum depression at the 3‐month assessment, and they reported a significantly higher EPDS composite score at 3 months’ postpartum. There was a significant relation between maternal depressive symptoms at 3 and 6 months and infants’ social withdrawal at 9 months, and a significant concurrent relation between the two variables at 6 and 9 months in the full‐term cohort. The findings suggest a need to screen for both infant social withdrawal and maternal depressive symptoms in moderately prematurely born infants and their caregivers.
SCREENING FOR SUSTAINED SOCIAL WITHDRAWAL BEHAVIORS IN SIX‐MONTH‐OLD INFANTS DURING PEDIATRIC PRIMARY CARE VISITS: RESULTS FROM AN AT‐RISK LATINO IMMIGRANT SAMPLE WITH HIGH RATES OF MATERNAL MAJOR DEPRESSIVE DISORDER
Authors: Burtchen Nina , Alvarez‐Segura Mar , Mendelsohn Alan L. , Dreyer Benard P. , Castellanos Francisco X. , Catapano Peter , Guedeney Antoine 
Published: October 2013

ABSTRACTTo examine relations between infant social withdrawal behavior and maternal major depression (MDD), 155 mother–infant dyads were evaluated at the 6‐month primary care visit. Maternal depression was determined based on a psychiatric interview. Infant social withdrawal behavior was assessed with the Alarm Distress Baby Scale (ADBB; A. Guedeney & J. Fermanian, 2001) based on videotaped mother–infant interactions. Of the sample, 18.7% of mothers were diagnosed with MDD, and 39.4% of infants scored above the clinical ADBB cutoff. Infants of depressed mothers were more likely to score positive on the ADBB (75.8 vs. 31.0%, p < .001) and showed distinct patterns of withdrawal behavior. Within the group of withdrawn infants, however, no differential patterns of behavior could be identified for infants of depressed mothers as compared to infants of mothers with no depression. These findings confirm the validity of the ADBB for detection of infant social withdrawal in the context of MDD. At the same time, they support evidence that the ADBB identifies nonspecific infant distress behaviors. Future studies will need to determine if and how positive ADBB screening results in the absence of maternal MDD might be associated with other maternal psychiatric disorders such as anxiety or borderline personality disorder. These results have important implications for screening guidelines in primary care.
Phage therapy and phage control: to be revisited urgently!!
Authors: Vandamme Erick J. 
Published: October 2013

AbstractPhage therapy has been a valuable asset since the 1920s to deal with pathogenic bacterial infections, and has been practised ever since, especially in the former Soviet Union and in eastern Europe. The western world remained sceptical and resorted to the widespread use of antibiotics as soon as they became available. Now that antibiotic resistance among pathogenic bacteria has spread alarmingly and no really new antibiotic compounds are in the pipeline, renewed attention should be directed to the use of phages as antimicrobials in medicine as well as in the health and the agro‐food sector. The history of early phage use, its successes and problems and the current developments in phage research, production and applications in phage control and therapy are critically reviewed in this context. © 2013 Society of Chemical Industry
Validation of a Survey for Graduate Teaching Assistants: Translating Theory to Practice
Authors: Zhu Jiabin , Li Yi , Cox Monica F. , London Jeremi , Hahn Jeeyeon , Ahn Benjamin 
Published: October 2013

AbstractBackgroundGraduate teaching assistants (GTAs) play important roles in undergraduate education. The improvement of GTAs' teaching skills relies on effective formative and summative feedback about their teaching. An absence of robust, theory‐driven feedback tools can limit the scope and the usefulness of feedback to GTAs.PurposeThis article focuses on the validation of a student survey that provides pedagogical feedback to GTAs. This survey's development was guided by the How People Learn (HPL) framework. Consisting of four dimensions (knowledge‐centeredness, learner‐centeredness, assessment‐centeredness, and community‐centeredness), this framework has been used to empirically assess GTA teaching and student learning, especially in engineering.MethodThe survey was validated using exploratory factor analysis (EFA) with prior external content validity checks. We used EFA to identify distinct factors in the survey. The analyses informed item development on the final survey that operationalized the dimensions of the HPL framework.ResultsWe produced a 29‐item survey informed by the HPL framework. Three distinct factors were identified in the survey structure after two rounds of EFA. These factors represent an individual dimension or a hybrid of dimensions of the HPL framework.ConclusionThis article describes the development of a survey that is ready for use by engineering GTAs to solicit feedback from students. From survey results, GTAs may obtain HPL‐based teaching profiles that translate theory to practice. Implications for practice are also provided to facilitate the implementation of the survey, to improve the effectiveness of GTA teaching, and to enhance engineering student learning.
Multiple echo multi‐shot diffusion sequence
Authors: Chabert Steren , Galindo César , Tejos Cristian , Uribe Sergio A. 
Published: October 2013

PurposeTo measure both transversal relaxation time (T2) and diffusion coefficients within a single scan using a multi‐shot approach. Both measurements have drawn interest in many applications, especially in skeletal muscle studies, which have short T2 values. Multiple echo single‐shot schemes have been proposed to obtain those variables simultaneously within a single scan, resulting in a reduction of the scanning time. However, one problem with those approaches is the associated long echo read‐out. Consequently, the minimum achievable echo time tends to be long, limiting the application of these sequences to tissues with relatively long T2.Materials and MethodsTo address this problem, we propose to extend the multi‐echo sequences using a multi‐shot approach, so that to allow shorter echo times. A multi‐shot dual‐echo EPI sequence with diffusion gradients and echo navigators was modified to include independent diffusion gradients in any of the two echoes.ResultsThe multi‐shot approach allows us to drastically reduce echo times. Results showed a good agreement for the T2 and mean diffusivity measurements with gold standard sequences in phantoms and in vivo data of calf muscles from healthy volunteers.ConclusionA fast and accurate method is proposed to measure T2 and diffusion coefficients simultaneously, tested in vitro and in healthy volunteers. J. Magn. Reson. Imaging 2014;39:1027–1032. © 2013 Wiley Periodicals, Inc.
Correlation between fractional anisotropy and motor outcomes in one‐year‐old infants with periventricular brain injury
Authors: Madhavan Sangeetha , Campbell Suzann K. , Campise‐Luther Rose , Gaebler‐Spira Deborah , Zawacki Laura , Clark April , Boynewicz Kara , Kale Dipti , Bulanda Michelle , Yu Jinsheng , Sui Yi , Zhou Xiaohong Joe 
Published: October 2013

PurposeTo determine whether motor outcomes of an exercise intervention beginning at 2 months corrected age (CA) in children with periventricular brain injury (PBI) are correlated with fractional anisotropy (FA) measures derived from diffusion tensor imaging (DTI) at 12 months CA.Materials and MethodsDTI was performed in eight infants with PBI who were randomly assigned to kicking and treadmill stepping exercise or a no‐training condition. Development was assessed using the Alberta Infant Motor Scale (AIMS) and the Gross Motor Function Classification System (GMFCS). FA values were derived from regions of interest (ROIs) in the middle third of the posterior limb of the internal capsule (PLIC) and the posterior thalamic radiation (PTR).ResultsSignificant correlations were observed between motor development and FA measures. For PLIC, the correlation coefficients were 0.82 between FA and AIMS, and −0.92 between FA and GMFCS, while for PTR the corresponding correlation coefficients were 0.73 and −0.80, respectively.ConclusionResults of this study suggest that quantitative evaluation of white matter tracts using DTI at 12 months CA may be useful for assessment of brain plasticity in children. J. Magn. Reson. Imaging 2014;39:949–957. © 2013 Wiley Periodicals, Inc.
Regional perfusion imaging using pTILT
Authors: Ouyang Cheng , Sutton Bradley P. 
Published: October 2013

PurposeTo demonstrate the feasibility that the pseudo‐continuous transfer insensitive labeling technique (pTILT) sequence can be modified to achieve regional perfusion imaging by either vessel‐encoded or vessel‐selective pTILT, similar to the regional perfusion imaging sequences using pseudo‐continuous arterial spin labeling (pCASL).Materials and MethodsStatic phantom experiments were carried out to investigate the selectivity and efficiency of region‐specific labeling by pTILT. The ability of the modified pTILT sequences to separate perfusion territories was also examined at two levels of the arterial tree on four healthy subjects: (i) the left and right internal carotid arteries (ICAs) and (ii) individual vascular territories of arteries above the circle of Willis (anterior cerebral artery [ACA], left and right middle cerebral arteries [MCAs]).ResultsIn the phantom study, compared with non–region‐specific pTILT, a labeling efficiency of 0.92 and 0.88 was measured at the target vessels using vessel‐encoded and vessel‐selective pTILT, respectively. In human studies, the perfusion territories of ACA, left and right MCA branches with estimated CBF of 74.5 ± 26.1, 65.9 ± 7.2, and 72.3 ± 14.5 mL/100 g/min, respectively, as well as more general left/right end territories (76.8 ± 12.7 and 72.8 ± 7.2 mL/100 g/min), were clearly delineated by the modified pTILT sequences for regional perfusion imaging.ConclusionTwo regional perfusion imaging modules (vessel‐encoded and vessel‐selective) used in pCASL can also be adapted into the pTILT sequence, and our results confirmed that the region‐specific pTILT sequence is capable of regional perfusion imaging to separate perfusion territories of major cerebral arteries. J. Magn. Reson. Imaging 2014;40:192–199. © 2013 Wiley Periodicals, Inc.
Anti‐HBs seroconversion during treatment with entecavir in a patient with chronic hepatitis B virus infection on hemodialysis
Authors: Spaziante Martina , Biliotti Elisa , Grieco Stefania , Palazzo Donatella , Esvan Rozenn , Taliani Gloria 
Published: October 2013

ABSTRACTHepatitis B (HBV) virus infection is one of the most important causes of liver disease in patients with end‐stage renal failure on hemodialysis. The natural history of chronic HBV infection acquired in childhood starts with an immune tolerant phase, followed by an immune clearance phase that may lead to the inactive carrier state or the development of chronic liver disease. Information on antiviral therapy administered very early during the immune clearance phase are lacking and no data exist on the treatment of early immune activation in the hemodialysis setting. This report describes the case of a patient affected by end‐stage renal failure and HBeAg‐positive chronic HBV virus infection treated very early during the immune clearance phase of HBV infection with an adjusted‐dose of nucleoside analogue entecavir. The patient achieved a very rapid HBV‐DNA undetectability, anti‐HBe, and anti‐HBs seroconversion. This is the first report of antiviral therapy with entecavir started during the immune reactive phase of HBV infection in a patient on hemodialysis and it suggests that antiviral treatment can enhance the effects of host immune activation resulting in biochemical, serological, and viral response, even in end‐stage renal failure patients with partial immunodeficiency. Antiviral therapy with entecavir in the setting of hemodialysis was safe and well tolerated. J. Med. Virol. 86:139–143, 2014. © 2013 Wiley Periodicals, Inc.
Irreproducible positive results on the Cobas AmpliPrep/Cobas TaqMan HIV‐1 Qual test are different qualitatively from confirmed positive results
Authors: Maritz Jean , van Zyl Gert U. , Preiser Wolfgang 
Published: October 2013

AbstractCriteria that define low positive results on the COBAS® AmpliPrep/COBAS® TaqMan (CAP/CTM) HIV‐1 Qual test as inconclusive have been adopted by all academic centres in South Africa that conduct infant HIV PCR, following previous investigations that showed poor specificity of these results. Retesting all inconclusive specimens has considerable cost implications. Therefore, it was attempted to characterise such inconclusive results, by comparing those that prove to be either negative or positive on follow‐up testing. This retrospective, laboratory‐based study found that 193 of 211 (91.5%) patients with previous inconclusive results (defined as reported positive by CAP/CTM but with cycle threshold [Ct] values of >32 and/or fluorescence intensity [FI] values of <5) tested negative and only 18 (8.5%) tested positive using independently obtained follow‐up samples after a median of 28 days. The only significant independent predictor of a later positive result was a higher FI value (3.326 vs. 0.495, P < 0.0001), whereas Ct values were not predictive independently. Specimens from patients negative on follow‐up testing differed qualitatively from specimens that proved to be true positives. As the lower FI values in false‐positive compared to true‐positive results probably are indicative of a non‐specific signal, the incorporation of stringent amplification slope criteria in the assay's test definition file may improve correct classification and thus reduce the need for repeat testing of a large number of inconclusive specimens. J. Med. Virol. 86:82–87, 2014. © 2013 Wiley Periodicals, Inc.
A novel mouse model of trauma induced heterotopic ossification
Authors: Liu Xuhui , Kang Heejae , Shahnazari Mohammad , Kim Hubert , Wang Liping , Larm Olla , Adolfsson Lars , Nissenson Robert , Halloran Bernard 
Published: October 2013

AbstractSevere soft tissue trauma is associated with heterotopic ossification (HO), the abnormal deposition of bone at extra‐skeletal sites. The pathophysiology of the development of trauma‐induced HO remains largely unknown due in part to the lack of appropriate animal models. In this study, we sought to develop a new trauma‐induced HO mouse model using muscle impact injury combined with low dose BMP‐2. BMP‐2 at doses ranging from 0 to 2 µg was injected into quadriceps muscles of adult male C57/BL6 mice. Animals then received a one‐time quadriceps impaction injury to mimic the trauma associated with severe injuries. HO was monitored using in vivo microCT scanning at 1, 2, 4, and 8 weeks after treatment. After trauma, the expression of BMP‐2, ‐4, BMP receptor 1, SOX9 and RUNX2 were increased in muscle. Although little or no HO was observed in mice receiving 1 µg BMP‐2, combining this dose with muscle trauma produced an abundance of HO. At higher doses of BMP‐2, trauma did not augment mineral deposition. These results suggest that BMP‐2 signaling can sensitize muscle to trauma‐induced HO. They also provide the basis for a new model to study the pathogenesis of trauma‐induced HO. © 2013 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 32:183–188, 2014.
Evaluation of total phenolics, flavonoids and antioxidant activity of 18 Korean onion cultivars: a comparative study
Authors: Sharma Kavita , Assefa Awraris D , Kim Seol , Ko Eun Young , Lee Eul Tai , Park Se Won 
Published: October 2013

AbstractBACKGROUNDOnion is undoubtedly one of the major sources of flavonoids. However, there exists a varietal difference in composition, concentration and beneficial activities of onion, on the basis of cultivars, day length sensitivity/ripening and types. To characterise such differences, 18 onion cultivars from Korean were evaluated for their total phenolics, flavonoids and antioxidant activity. Simultaneous quantification of quercetin, quercetin‐3,4′‐O‐diglucoside, quercetin‐4′‐O‐monoglucoside and isorhamnetin‐3‐glucoside was made in methanol and 75% ethanol.RESULTSTotal phenolic content was examined spectrophotometrically with the Folin–Ciocalteu phenol reagent and total antioxidant activity were studied by the ferric reducing antioxidant power (FRAP) and diphenyl picryl hydrazyl (DPPH) methods. The cultivar ‘Sunpower’ showed the highest level of total phenolics [5016 ± 30.0 µg gallic acid equivalents g−1 dry weight (DW)] and flavonoids (2873.95 ± 60.01 µg Q g−1 DW) among the 18 cultivars in methanol. However, there were fewer total phenolics and flavonoids in ethanol extracts. The antioxidant activity for cultivar Sunpower was highest in ethanol extracts 24.12 ± 1.00 and 16.13 ± 0.35 µmol L−1 Trolox equivalents g−1 DW with FRAP and DPPH, respectively.CONCLUSIONAmong the 18 cultivars, Sunpower is the most promising in terms of total phenolics, total flavonoids and antioxidant activity. Our results suggest that day length sensitivity/ripening among the cultivars do not play any significant role for high values of total phenolics, flavonoids and antioxidant activity. © 2013 Society of Chemical Industry
Single and fused transgenic Bacillus thuringiensis rice alter the species‐specific responses of non‐target planthoppers to elevated carbon dioxide and temperature
Authors: Wan Guijun , Dang Zhihao , Wu Gang , Parajulee Megha N , Ge Feng , Chen Fajun 
Published: October 2013

AbstractBACKGROUNDThe approval of transgenic Bacillus thuringiensis (Bt) rice by China was momentous for biotech crops, although it has yet to be approved for commercial production. Non‐target pest problems in rice paddies, such as the three ecologically similar species of planthoppers Nilaparvata lugens, Laodelphax striatellus and Sogatella furcifera, could become increasingly serious under global climate change. Fused (Cry1Ab/Cry1Ac) and single (Cry1Ab) transgenic Bt rice were evaluated for effects on species‐specific responses of planthoppers to elevated carbon dioxide (CO2) and temperature.RESULTSTransgenic Bt rice lines significantly modified species‐specific responses of the planthoppers to elevated CO2 and temperature. High temperature appears to favour outbreaks of S. furcifera relative to N. lugens and L. striatellus when feeding upon fused transgenic Bt rice, especially at elevated CO2. Elevated CO2 at high temperature appears to be a factor reducing S. furcifera occurrence when feeding upon single transgenic Bt rice.CONCLUSIONDifferent types of transgenic Bt rice alter the species‐specific responses of non‐target planthoppers to elevated CO2 and temperature. Compared with their non‐transgenic parental lines, the single transgenic Bt rice shows better performance in controlling the non‐target planthopper S. furcifera by comparison with the fused transgenic Bt rice under elevated CO2 and temperature. It is suggested that multitypes of transgenic Bt rice be used in the field simultaneously in order to take advantage of high transgenic diversity for optimal performance against all pests in paddy fields. © 2013 Society of Chemical Industry
Youth advisory structures: Listening to young people to support quality youth services
Authors: Roholt Ross VeLure , Mueller Megan 
Published: October 2013

AbstractCreating structures to include young people's opinions and advice has been recognized as important for high‐quality youth programs and services. Recent scholarship has begun to learn that most of these efforts are often symbolic rather than substantive. While continually advocated for, the practice is not widespread or well done. Using data from a statewide study of youth advisory structures and a case study of one advisory structure used within a municipal parks and recreation center, this article describes what both of these teach about creating substantive, meaningful, and useful youth advisory structure for program and organization development.
Electronic Structure and Magnetic Properties of Chromium Chalcogenides and Pnictides with NiAs Structure
Authors: Polesya Svitlana , Kuhn Gerhard , Benea Diana , Mankovsky Sergiy , Ebert Hubert 
Published: October 2013

Abstract The structural as well as electronic and magnetic properties of chromium chalcogenides and pnictides with NiAs structure were studied using the Korringa‐Kohn‐Rostoker (KKR) band structure method. The magnetic properties at finite temperature were investigated by means of Monte Carlo simulations on the basis of a classical Heisenberg Hamiltonian and the exchange coupling parameters calculated from first principles. Combination of ab initio electronic structure calculations with Monte Carlo simulations allowed to investigate both the ground state magnetic properties as well as the finite‐temperature properties. In the case of stoichiometric systems, these calculations allowed to explain the origin of magnetic structures in this system as observed experimentally. In case of non‐stoichiometric Cr‐(Te, Se) alloys the origin of finite‐temperature spin‐glass and cluster‐glass behaviors was clarified. In all cases a reasonable agreement with the experiment was obtained for the value of the critical temperature.