bluuebunny/crossref_metadata_2025_split huggingface dataset:
Manual therapy for the management of pain and limited range of motion in subjects with signs and symptoms of temporomandibular disorder: a systematic review of randomised controlled trials
Authors: Calixtre L. B. , Moreira R. F. C. , Franchini G. H. , Alburquerque‐Sendín F. , Oliveira A. B. 
Published: June 2015

SummaryThere is a lack of knowledge about the effectiveness of manual therapy (MT) on subjects with temporomandibular disorders (TMD). The aim of this systematic review is to synthetise evidence regarding the isolated effect of MT in improving maximum mouth opening (MMO) and pain in subjects with signs and symptoms of TMD. MEDLINE®, Cochrane, Web of Science, SciELO and EMBASE™ electronic databases were consulted, searching for randomised controlled trials applying MT for TMD compared to other intervention, no intervention or placebo. Two authors independently extracted data, PEDro scale was used to assess risk of bias, and GRADE (Grading of Recommendations Assessment, Development and Evaluation) was applied to synthetise overall quality of the body of evidence. Treatment effect size was calculated for pain, MMO and pressure pain threshold (PPT). Eight trials were included, seven of high methodological quality. Myofascial release and massage techniques applied on the masticatory muscles are more effective than control (low to moderate evidence) but as effective as toxin botulinum injections (moderate evidence). Upper cervical spine thrust manipulation or mobilisation techniques are more effective than control (low to high evidence), while thoracic manipulations are not. There is moderate‐to‐high evidence that MT techniques protocols are effective. The methodological heterogeneity across trials protocols frequently contributed to decrease quality of evidence. In conclusion, there is widely varying evidence that MT improves pain, MMO and PPT in subjects with TMD signs and symptoms, depending on the technique. Further studies should consider using standardised evaluations and better study designs to strengthen clinical relevance.
Propranolol in the Treatment of Infantile Hemangiomas: A Meta‐Analysis in Chinese Patients
Authors: Li Lin‐Lin , Yan Lu , Luo Miao‐Xuan , Cai Yi‐Xuan , Mi Xiang‐Bin , Zhang Tang‐De 
Published: June 2015

AbstractA meta‐analysis was conducted to evaluate the efficacy of propranolol in the treatment of infantile hemangiomas (IHs) in Chinese infants. A statistically significant difference was found between infants treated using propranolol and those treated using corticosteroids (p < 0.001). The total effect pooled from 26 single‐arm studies using meta‐analysis of propranolol on IHs in Chinese infants was 93% (95% confidence interval 0.88, 0.96).
Fair Housing Enforcement in the South and Non‐South*
Authors: Bullock Charles S. , Wilk Eric M. , Lamb Charles M. 
Published: June 2015

ObjectiveWe compare outcomes in racial discrimination fair housing complaints processed by southern state and local civil rights agencies to those handled by state and local agencies outside the South and the federal agency, HUD (Department of Housing and Urban Development).MethodsBased on data obtained directly from HUD, we rely on a fixed effects logistic regression model with cluster‐correlated standard errors.ResultsFirst, southern local agencies are significantly more likely to provide outcomes favorable to complainants in racial discrimination fair housing cases than are local agencies outside the South. Second, state and local agencies in the Deep South provide favorable outcomes to the same extent as their nonsouthern counterparts. Third, southern local agencies are more likely to provide favorable outcomes than is HUD, whereas southern state agencies provide favorable outcomes at roughly the same rate as HUD. Variations within the South partially explain these findings.ConclusionWe find evidence of progressive changes in southern fair housing enforcement, although those changes occur in an uneven fashion depending on the state or locality.
Exceptionally long‐term survival of a dog with gastric lymphoma and concurrent dietary intolerance
Authors: Ruiz Guillaume , Reyes Gomez Edouard , Yaguiyan‐Colliard Laurence 
Published: June 2015

A 10‐year‐old Jack Russell Terrier presented with a six‐month history of chronic vomiting. Initial bloodwork and ultrasound demonstrated mild and non‐specific changes. Vomiting dramatically improved upon feeding a home‐made elimination diet, and clinical signs reappeared following a provocation trial. However, 12 weeks after the first visit, the dog became inappetent and lost weight despite this food change. A gastroscopy was performed, and histological examination of gastric mucosal samples revealed high‐grade B‐cell lymphoma, which was confirmed on immunohistochemistry. Systemic chemotherapy was initiated, and the dog survived 30 months on treatment. This is an exceptional long‐term survival time of a dog presenting a gastric lymphoma and concurrent dietary intolerance.
Distinct sea-level fluctuations and deposition of a megaclast horizon in the neritic Rauchkofel Limestone (Wolayer area, Carnic Alps) correlate with the Lochkov–Prag Event
Authors: Suttner T. J. , Kido E. 
Published: June 2015

Abstract
Distinctive facies change and magnetic susceptibility across the neritic Rauchkofel Limestone (Central Carnic Alps) document specific sea-level fluctuations that are related to the Lochkov–Prag Event. This is supported by a positive shift in the carbon isotope signal of about 1.5‰ and a distinct decline in conodont biodiversity during the late Lochkovian. A transgressive interval during the late Lochkovian is followed by a regressive phase indicated by an eye-catching megaclast horizon of early Pragian age. Some of the boulders within that horizon reach up to 10 m in diameter. A model explaining regional depositional patterns is provided.
Towards a global humanitarian volcano impact alert model integrated into a multi-hazard system
Authors: Andredakis Ioannis , De Groeve Tom 
Published: June 2015

Abstract
Volcanic eruptions pose a significant risk to human lives, property and infrastructure, despite rapid advances in monitoring and early warning science and technology. Some elements of risk – such as the number of people living close to volcanoes – are increasing, and the unpredictable nature of eruptions may overwhelm the local response capacity and turn into a disaster, sometimes requiring international assistance. To deal effectively with these crises, the international humanitarian community needs a global, science-based early warning system that should assimilate the state-of-the-art monitoring and early warning techniques, as well as being able to provide a preliminary impact assessment, and issue appropriate and relevant alerts. Current volcano warning systems are either only local in context or are not suited to the needs of global early warning. In this paper we propose an outline for a volcano warning system aimed at issuing alerts to the humanitarian aid community. It is designed as a four-level system, incorporating the latest monitoring and hazard modelling techniques that are applicable on a global scale. Alerts are mainly based on the predicted humanitarian impact of the modelled hazards. Systematic handling of volcanic manifestations, such as thermal signals and ash clouds from space-borne instruments, make it possible to create such a system. The Global Disaster Alert and Coordination System (GDACS), a joint effort by the United Nations and the European Commission, has been operating in a similar spirit for other natural disasters for a number of years and could fulfil the role of the desired volcano system. This paper discusses the needs and issues of this undertaking.
Pro-inflammatory cytokines reduce human TAFI expression via tristetraprolin-mediated mRNA destabilisation and decreased binding of HuR
Authors: Komnenov Dragana , Scipione Corey , Bazzi Zainab , Garabon Justin , Koschinsky Marlys , Boffa Michael 
Published: June 2015

SummaryThrombin activatable fibrinolysis inhibitor (TAFI) is the zymogen form of a basic carboxypeptidase (TAFIa) with both anti-fibrinolytic and anti-inflammatory properties. The role of TAFI in inflammatory disease is multifaceted and involves modulation both of specific inflammatory mediators as well as of the behaviour of inflammatory cells. Moreover, as suggested by in vitro studies, inflammatory mediators are capable of regulating the expression of CPB2, the gene encoding TAFI. In this study we addressed the hypothesis that decreased TAFI levels observed in inflammation are due to post-transcriptional mechanisms. Treatment of human HepG2 cells with pro-inflammatory cytokines TNFα, IL-6 in combination with IL-1β, or with bacterial lipopolysaccharide (LPS) decreased TAFI protein levels by approximately two-fold over 24 to 48 hours of treatment. Conversely, treatment of HepG2 cells with the anti-inflammatory cytokine IL-10 increased TAFI protein levels by two-fold at both time points. We found that the mechanistic basis for this modulation of TAFI levels involves binding of tristetraprolin (TTP) to the CPB2 3′-UTR, which mediates CPB2 mRNA destabilisation. In this report we also identified that HuR, another ARE-binding protein but one that stabilises transcripts, is capable of binding the CBP2 3’UTR. We found that pro-inflammatory mediators reduce the occupancy of HuR on the CPB2 3’-UTR and that the mutation of the TTP binding site in this context abolishes this effect, although TTP and HuR appear to contact discrete binding sites. Interestingly, all of the mediators tested appear to increase TAFI protein expression in THP-1 macrophages, likewise through effects on CPB2 mRNA stability.
Cleaved high-molecular-weight kininogen inhibits neointima formation following vascular injury
Authors: Daniel Jan-Marcus , Reich Fabian , Dutzmann Jochen , Weisheit Simona , Teske Rebecca , Gündüz Dursun , Bauersachs Johann , Preissner Klaus , Sedding Daniel 
Published: June 2015

SummaryCleaved high-molecular-weight kininogen (HKa) or its peptide domain 5 (D5) alone exert anti-adhesive properties in vitro related to impeding integrin-mediated cellular interactions. However, the anti-adhesive effects of HKa in vivo remain elusive. In this study, we investigated the effects of HKa on leukocyte recruitment and neointima formation following wire-induced injury of the femoral artery in C57BL/6 mice. Local application of HKa significantly reduced the accumulation of monocytes and also reduced neointimal lesion size 14 days after injury. Moreover, C57BL/6 mice transplanted with bone marrow from transgenic mice expressing enhanced green fluorescence protein (eGFP) showed a significantly reduced accumulation of eGFP+-cells at the arterial injury site and decreased neointimal lesion size after local application of HKa or the polypeptide D5 alone. A differentiation of accumulating eGFP+-cells into highly specific smooth muscle cells (SMC) was not detected in any group. In contrast, application of HKa significantly reduced the proliferation of locally derived neointimal cells. In vitro, HKa and D5 potently inhibited the adhesion of SMC to vitronectin, thus impairing their proliferation, migration, and survival rates. In conclusion, application of HKa or D5 decreases the inflammatory response to vascular injury and exerts direct effects on SMC by impeding the binding of integrins to extracellular matrix components. Therefore, HKa and D5 may hold promise as novel therapeutic substances to prevent neointima formation.
Magnetic Resonance Imaging and Tissue Characterization of a Renal Cell Carcinoma and its Osseous Metastasis
Authors: Pettersson H. , Springfield D. , Hamlin D. , Scott K. 
Published: June 2015

A patient with renal cell carcinoma, first presenting because of symptoms from an osseous metastasis, was examined with CT and magnetic resonance imaging (MRI). Both the primary tumor and the metastasis were well demonstrated by both methods. MRI tissue characterization showed that the T1 values in the kidney and the metatasis were the same, as were the T2 values. This may mean a potential for the MRI to define primary tumors when a metastasis is found. Malignant disease frequently manifests with symptoms from metastatic spread. This presents the diagnostic challenge of detection of the primary tumor site. In this search, radiologic methods are important tools. The radiologic arsenal recently has been strengthened with a new modality, magnetic resonance imaging (MRI), and we now present the first case that seems to be reported of MRI depiction and tissue characterization of a renal cell carcinoma, first presenting as an osseous metastasis.
Computed Tomography in Pre- and Postoperative Evaluation of Aortic Dissection
Authors: Landtman M. , Kivisaari L. , Standertskjöld-Nordenstam C.-G. , Taavitsainen M. 
Published: June 2015

Thirty-seven patients with angiographically or operatively confirmed acute, chronic or postoperative aortic dissection were examined by means of dynamic CT and the results compared with those obtained by angiography and ultrasonography (US). The diagnostic accuracy was 87 per cent for CT, 97 per cent for angiography, and 76 per cent for US, although US was only available in less than half of the cases. The highest accuracy (95%) of CT was achieved in the pre-operative group, which is comparable with the 97 per cent accuracy achieved using angiography. Three patients in the postoperative group had false negative CTs, resulting in an overall accuracy of 82 per cent as compared with 100 per cent for angiography. Despite its diagnostic capacity, CT could not define the complete extent of dissection in four patients. The descending thoracic aorta was the area most difficult for CT examinations because of frequent artifacts in the images. References
Selective Streptokinase Fibrinolysis in Femoro-Iliac Arterial Obstruction
Authors: Sørensen K. , Hegedüs V. 
Published: June 2015

Percutaneous transluminal angioplasty of iliac and femoral arteries was in 17 patients combined with selective intra-arterial streptokinase treatment. The patients were divided into two groups, one given low dose long-term therapy and the other high dose short-term therapy. The experiences obtained during an observation period of over one year revealed greater benefit from high dose short-term therapy. It seems that the major cause of complications must be attributed to the development of a high level of streptokinase antibodies during low dose long-term therapy. References
Radiologic Evaluation of the Continent (S-Pouch) Ileal Reservoir with Anal Anastomosis
Authors: Hennild V. , Kjærgård H. , Hansen L. Kuld 
Published: June 2015

A radiologic investigation was performed in 26 patients subjected to colectomy, mucosal proctectomy and endorectal ileo-anal anastomosis after the creation of an ileal reservoir. The patients had suffered from ulcerative colitis or familial polyposis. The reservoir and its efferent leg was best demonstrated by contrast enema. The size and position of the reservoir and the efferent leg was demonstrated, and stenoses, abscesses and fistulae could be identified. Examination of the small bowel with a contrast medium showed slight dilatation of the ileum orally to the reservoir in all instances and one patient had a stenosis at the junction of the afferent leg of the reservoir. Erect and supine projections of the abdomen showed gas in the intestine and fluid levels in the reservoir. These radiographic findings should not be confused with ileus or pelvic abscess. Radiology was of great value in disclosing postoperative complications. References
Computed Tomography of the Knee with Reference to Meniscal Tears
Authors: Jurik A. G. , Jørgensen J. , Helmig O. , de Carvalho A. 
Published: June 2015

Computed tomography (CT) with a high resolution CT scanner and—on a special occasion—double contrast arthrography of the knee with reference to meniscal tears were performed in 50 patients. Operation or arthroscopy was performed in 28 patients and 15 were found to have meniscal tears. A correct diagnosis of the tears was achieved at CT in 13 of these patients. Three false positive and two false negative CT findings were recorded, resulting in a 91 per cent accuracy for CT, a diagnostic specificity of 84 per cent, and a sensitivity of 95 per cent. The diagnostic value of CT thus compared with that of double contrast arthrography. This should indicate that CT may be used as an alternative non-invasive diagnostic procedure in the diagnosis of meniscal tears of the knee joint. References
Tracheobronchial Calcification in Members of a Fixed Population Sample
Authors: Fukuya T. , Mihara F. , Kudo S. , Russell W. J. , DeLongchamp R. R. , Vaeth M. , Hosoda Y. 
Published: June 2015

The Radiation Effects Research Foundation (formerly, Atomic Bomb Casualty Commission; ABCC) was established in April 1975 as a private non-profit Japanese Foundation, supported equally by the Government of Japan through the Ministry of Health and Welfare, and the Government of the United States through the National Academy of Sciences under contract with the United States Department of Energy. Accepted 4 December 1988. In a review of the chest radiographs of 1 152 consecutively examined subjects, 10 cases (0.87%) of extensive tracheobronchial calcification were identified. In addition, 51 subjects having this coded diagnosis were identified among 11758 members of a fixed population sample. Sixty of these 61 subjects were women. Tracheobronchial calcification usually appeared after the age of 60. The subjects' clinical and other radiologic diagnoses were reviewed and tracheobronchial calcification appeared to have no clinical significance. Histologic findings in autopsied cases showed the calcifications and ossificiations to be in the cartilaginous rings themselves. However, the reason for the overwhelming prevalence of this entity in women remains to be resolved.
Ear Workshop on Education in Radiology in Europe, Held in Berlin/GDR on
Authors: Tessier J. P. , Lüning M. , Delorme G. , Natho W. 
Published: June 2015

The workshop on Education in Radiology in Europe was held in Berlin on October 21st 1988, organized by the Commission of Education of the European Association of Radiology (EAR). Thirty-three representatives from 20 countries took part in this workshop, as well as 23 GDR university teachers and one radiologist from China as guests. This workshop was preceded by an inquiry among all EAR member countries on the following subjects, and the results of this inquiry were included in the report and the discussion.
Comparative Study of the Dialysability of Iobitridol and Iohexol in the Rat with Impaired Renal Function
Authors: Dencausse A. , Chambon C. , Violas X. , Bonnemain B. 
Published: June 2015

Purpose: To assess the dialysability of iobitridol, a comparative study with iohexol was conducted in the rat over 4 hours. Material and Methods: After ligature of the renal veins and arteries, a group of animals was submitted to continuous peritoneal dialysis, while the remainder were not. Results: In the event of total renal failure, biliary excretion rose from 0.4 to 9% for iobitridol and from 2 to 16% for iohexol. In the rats submitted to peritoneal dialysis, biliary excretion decreased to 5% in the iobitridol group and to 13% in the iohexol group. Further, 18% of the test substances were eliminated in the dialysis liquid. Conclusions: As their physicochemical characteristics are very similar, the differences between the biliary excretion levels of these 2 media may be caused by a factor related to their respective molecular conformations.
CT-Diskography, Diskomanometry and MR Imaging as Predictors of the Outcome of Lumbar Percutaneous Automated Nucleotomy
Authors: Dullerud R. , Amundsen T. , Lie H. , Juel N. G. , Magnæs B. 
Published: June 2015

Purpose: This prospective study was performed to assess whether CT-diskography (CT-D), diskomanometry (DMM) including recording of the pain response, or the MR signal intensity of the disks are reliable predictors of the outcome of nucleotomy. Material and Methods: Ninety-one patients, 44 females and 47 males aged 18–68 years (mean 37.4) treated at 99 disk levels were included. All had plain CT, MR imaging, CT-D and DMM performed prior to automated percutaneous nucleotomy with the Nucleotome R system. Results: Sixty-nine (76%) of the patients responded well to treatment within 3 months. Due to recurrences, the success rate at 1 year was reduced to 65%. Except for better results following nucleotomy in patients with similar and identical pain as the presenting complaint provoked at diskography, no association was demonstrated between diskographic parameters, or loss of signal on MR, and the outcome. Better results were also seen in patients with a short history of disk disease, but not in patients with predominantly sciatica and focal hernias compared to those with predominantly low-back pain and diffuse posterior bulges. Conclusion: The results do not justify routine use of diskography prior to nucleotomy in patients with pathologic disks demonstrated by noninvasive methods and localizing sciatic pain.
CT-Assessment of Dependent Lung Densities in Man during General Anaesthesia
Authors: Lundquist H. , Hedenstierna G. , Strandberg Å. , Tokics L. , Brismar B. 
Published: June 2015

Purpose: We aimed to describe the frequency of atelectasis occurring during anaesthesia, to describe the size and pattern of the atelectasis, and to standardise the method of identifying the atelectasis and calculate its area. Material and Methods: Patients (n=109) scheduled for elective abdominal surgery were examined with CT of the thorax during anaesthesia. Results: In 95 patients (87%) dependent pulmonary densities were seen, interpreted as atelectasis. Two different types of atelectasis were found — Homogeneous (78%) and non-homogeneous (9%). Attenuation values in histograms of the lung and atelectasis were studied using 2 methods of calculating the atelectatic area. Conclusion: On the basis of the present findings, we defined atelectasis as pulmonary dependent densities with attenuation values of —100 to +100 HU.
Neural Tolerance of the Non-Ionic Dimers Iodixanol and Iotrolan and the Non-Ionic Monomer Iopamidol during Myelography in Non-Anaesthetised Rabbits
Authors: Maly P. , Sundgren P. , Bååth L. , Walday P. 
Published: June 2015

Purpose: The neural tolerance of the recently introduced dimer iodixanol (320 g I/l) was compared with that of the dimer iotrolan (300 g I/l) and of the monomer iopamidol (300 g I/l), both used in clinical myelography. Material and Methods: Non-anaesthetised rabbits were injected into the cisterna magna with Ringer's solution (control) or contrast media (CM) at doses of 1.0 or 0.5 ml/kg b.w. The behaviour of the animals (10 in each of 7 groups) was evaluated for signs of excitation and depression during the first 3 hours after injection. Results: At the dose level of 1.0 ml/kg b.w., iodixanol produced no seizures but did cause focal twitching in 4/10 rabbits. Iopamidol produced grand mal seizures in 2/10 and hyperexcitability in 4/10 rabbits. Iotrolan produced generalised grand mal seizures in 8/10 rabbits, an incidence of excitation significantly greater than that of iodixanol (p<0.01) and iopamidol (p<0.05). The excitative effects of iodixanol were not significantly different from those of iopamidol and Ringer's solution. All 3 CM produced similar depressive effects on rabbit behaviour. Ringer's solution caused no depressive effects (p<0.01). A clear dose response was produced with all 3 CM after treatment with a lower dose of 0.5 ml/kg b.w. Conclusion: The results indicate that the neural tolerance in the rabbit of iodixanol is higher than that of iotrolan, and is at least equal to that of iopamidol.