bluuebunny/crossref_metadata_2025_split huggingface dataset:
Deep Convective Systems Observed by A-Train in the Tropical Indo-Pacific Region Affected by the MJO
Authors: Yuan Jian , Houze Robert A. 
Published: September 2012

AbstractIn the Indo-Pacific region, mesoscale convective systems (MCSs) occur in a pattern consistent with the eastward propagation of the large-scale convective envelope of the Madden–Julian oscillation (MJO). MCSs are major contributors to the total precipitation. Over the open ocean they tend to be merged or connected systems, while over the Maritime Continent area they tend to be separated or discrete. Over all regions affected by the MJO, connected systems increase in frequency during the active phase of the MJO. Characteristics of each type of MCS (separated or connected) do not vary much over MJO-affected regions. However, separated and connected MCSs differ in structure from each other. Connected MCSs have a larger size and produce less but colder-topped anvil cloud. For both connected and separated MCSs, larger systems tend to have colder cloud tops and less warmer-topped anvil cloud. The maximum height of MCS precipitating cores varies only slightly, and the variation is related to sea surface temperature. Enhanced large-scale convection, greater frequency of occurrence of connected MCSs, and increased midtroposphere moisture coincide, regardless of the region, season, or large-scale conditions (such as the concurrent phase of the MJO), suggesting that the coexistence of these phenomena is likely the nature of deep convection in this region. The increase of midtroposphere moisture observed in all convective regimes during large-scale convectively active phases suggests that the source of midtroposphere moisture is not local or instantaneous and that the accumulation of midtroposphere moisture over MJO-affected regions needs to be better understood.
Tropical Precipitation Extremes
Authors: Rossow William B. , Mekonnen Ademe , Pearl Cindy , Goncalves Weber 
Published: September 2012

AbstractClassifying tropical deep convective systems by the mesoscale distribution of their cloud properties and sorting matching precipitation measurements over an 11-yr period reveals that the whole distribution of instantaneous precipitation intensity and daily average accumulation rate is composed of (at least) two separate distributions representing distinctly different types of deep convection associated with different meteorological conditions (the distributions of non-deep-convective situations are also shown for completeness). The two types of deep convection produce very different precipitation intensities and occur with very different frequencies of occurrence. Several previous studies have shown that the interaction of the large-scale tropical circulation with deep convection causes switching between these two types, leading to a substantial increase of precipitation. In particular, the extreme portion of the tropical precipitation intensity distribution, above 2 mm h−1, is produced by 40% of the larger, longer-lived mesoscale-organized type of convection with only about 10% of the ordinary convection occurrences producing such intensities. When average precipitation accumulation rates are considered, essentially all of the values above 2 mm h−1 are produced by the mesoscale systems. Yet today’s atmospheric models do not represent mesoscale-organized deep convective systems that are generally larger than current-day circulation model grid cell sizes but smaller than the resolved dynamical scales and last longer than the typical physics time steps. Thus, model-based arguments for how the extreme part of the tropical precipitation distribution might change in a warming climate are suspect.
1980–2010 Variability in U.K. Surface Wind Climate
Authors: Earl Nick , Dorling Steve , Hewston Richard , von Glasow Roland 
Published: September 2012

Abstract
The climate of the northeast Atlantic region comprises substantial decadal variability in storminess. It also exhibits strong inter- and intra-annual variability in extreme high and low wind speed episodes. Here the authors quantify and discuss causes of the variability seen in the U.K. wind climate over the recent period 1980–2010. Variations in U.K. hourly mean (HM) wind speeds, in daily maximum gust speeds and in associated wind direction measurements, made at standard 10-m height and recorded across a network of 40 stations, are considered. The Weibull distribution is shown to generally provide a good fit to the hourly wind data, albeit with the shape parameter k spatially varying from 1.4 to 2.1, highlighting that the commonly assumed k = 2 Rayleigh distribution is not universal. It is found that the 10th and 50th percentile HM wind speeds have declined significantly over this specific period, while still incorporating a peak in the early 1990s. The authors' analyses place the particularly “low wind” year of 2010 into longer-term context and their findings are compared with other recent international studies. Wind variability is also quantified and discussed in terms of variations in the exceedance of key wind speed thresholds of relevance to the insurance and wind energy industries. Associated interannual variability in energy density and potential wind power output of the order of ±20% around the mean is revealed. While 40% of network average winds are in the southwest quadrant, 51% of energy in the wind is associated with this sector. The findings are discussed in the context of current existing challenges to improve predictability in the Euro-Atlantic sector over all time scales.
Changes in Cloud Cover, Precipitation, and Summer Temperature in North America from 1982 to 2009
Authors: Tang Qiuhong , Leng Guoyong 
Published: September 2012

Abstract
In North America (NA), trends in summer surface air temperatures vary on decadal time scales, and some regions have temperature trends that exhibit a lack of warming in 1982–2009. From a surface energy balance perspective, the summer mean daily maximum temperature change can be affected by changes in solar heating that are associated with cloud cover change and changes in surface evaporative cooling caused by different precipitation and land surface wetness, but little is known about regional cloud cover and precipitation feedbacks to decadal temperature trends. Changes in cloudiness and precipitation and their connections with summer mean daily maximum temperature variations in NA were investigated using observation-based products of temperature and precipitation and satellite-derived cloud cover and radiation products. Results show that summer mean daily maximum temperature variance is largely explained by changes in cloud cover and precipitation. Cloud cover effect dominates at the high and middle latitudes of NA, and precipitation is a more dominant factor in the southern United States. The results indicate that cloud cover is either the major indicator of the summer mean daily maximum temperature changes (the effect) or the important local factor influencing the changes (the cause). Cloud cover is negatively correlated with mean daily maximum temperature variation in spring and autumn at the middle latitudes of NA but not at the high latitudes.
Warming of the Intermediate Atlantic Water of the Arctic Ocean in the 2000s
Authors: Polyakov Igor V. , Pnyushkov Andrey V. , Timokhov Leonid A. 
Published: September 2012

Abstract
This analysis evaluates the thermal state of the intermediate (depth range of 150–900 m) Atlantic Water (AW) of the Arctic Ocean, beginning in the 1950s and with particular focus on the transition from the 1990s to the 2000s and on changes during the 2000s. Using an extensive array of observations, the authors document AW warming trends across various time scales and demonstrate that the 2000s were exceptionally warm, with no analogy since the 1950s or probably in the history of instrumental observations in the Arctic Ocean. Warming in the recent decade was dominated by a warm AW pulse in addition to the underlying trend. Since 1997, the Canadian Basin experienced a faster warming rate compared with the Eurasian Basin. The relative role of the AW warmth in setting the net energy flux and mass balance of the Arctic sea ice is still under debate. Additional carefully orchestrated field experiments are required in order to address this question of ongoing Arctic climate change.
Vertical Eddy Energy Fluxes in the North Atlantic Subtropical and Subpolar Gyres
Authors: Zhai Xiaoming , Marshall David P. 
Published: September 2012

Abstract
Eddy energy generation and energy fluxes are examined in a realistic eddy-resolving model of the North Atlantic. Over 80% of the wind energy input is found to be released by the generation of eddies through baroclinic instability. The eddy energy generation is located near the surface in the subtropical gyre but deeper down in the subpolar gyre. To reconcile the mismatch between the depth of eddy energy production and the vertical structure of the horizontal dispersion of eddy energy, the vertical eddy energy flux is downward in the subtropical gyre and upward in the subpolar gyre.
Transcriptomic analysis of the red seaweed Laurencia dendroidea (Florideophyceae, Rhodophyta) and its microbiome
Authors: de Oliveira Louisi Souza , Gregoracci Gustavo Bueno , Silva Genivaldo Gueiros Zacarias , Salgado Leonardo Tavares , Filho Gilberto Amado , Alves-Ferreira Marcio , Pereira Renato Crespo , Thompson Fabiano L 
Published: September 2012

AbstractBackgroundSeaweeds of theLaurenciagenus have a broad geographic distribution and are largely recognized as important sources of secondary metabolites, mainly halogenated compounds exhibiting diverse potential pharmacological activities and relevant ecological role as anti-epibiosis. Host-microbe interaction is a driving force for co-evolution in the marine environment, but molecular studies of seaweed-associated microbial communities are still rare. Despite the large amount of research describing the chemical compositions ofLaurenciaspecies, the genetic knowledge regarding this genus is currently restricted to taxonomic markers and general genome features. In this work we analyze the transcriptomic profile ofL.dendroideaJ. Agardh, unveil the genes involved on the biosynthesis of terpenoid compounds in this seaweed and explore the interactions between this host and its associated microbiome.ResultsA total of 6 transcriptomes were obtained from specimens ofL. dendroideasampled in three different coastal locations of the Rio de Janeiro state. Functional annotations revealed predominantly basic cellular metabolic pathways. Bacteria was the dominant active group in the microbiome ofL.dendroidea, standing out nitrogen fixing Cyanobacteria and aerobic heterotrophic Proteobacteria. The analysis of the relative contribution of each domain highlighted bacterial features related to glycolysis, lipid and polysaccharide breakdown, and also recognition of seaweed surface and establishment of biofilm. Eukaryotic transcripts, on the other hand, were associated with photosynthesis, synthesis of carbohydrate reserves, and defense mechanisms, including the biosynthesis of terpenoids through the mevalonate-independent pathway.ConclusionsThis work describes the first transcriptomic profile of the red seaweedL.dendroidea, increasing the knowledge about ESTs from the Florideophyceae algal class. Our data suggest an important role forL. dendroideain the primary production of the holobiont and the role of Bacteria as consumers of organic matter and possibly also as nitrogen source. Furthermore, this seaweed expressed sequences related to terpene biosynthesis, including the complete mevalonate-independent pathway, which offers new possibilities for biotechnological applications using secondary metabolites fromL. dendroidea.
Clinical isolates of Yersinia enterocolitica Biotype 1A represent two phylogenetic lineages with differing pathogenicity-related properties
Authors: Sihvonen Leila M , Jalkanen Kaisa , Huovinen Elisa , Toivonen Susanna , Corander Jukka , Kuusi Markku , Skurnik Mikael , Siitonen Anja , Haukka Kaisa 
Published: September 2012

AbstractBackgroundY. enterocoliticabiotype (BT) 1A strains are often isolated from human clinical samples but their contribution to disease has remained a controversial topic. Variation and the population structure among the clinicalY. enterocoliticaBT 1A isolates have been poorly characterized. We used multi-locus sequence typing (MLST), 16S rRNA gene sequencing, PCR forystAandystB, lipopolysaccharide analysis, phage typing, human serum complement killing assay and analysis of the symptoms of the patients to characterize 298 clinicalY. enterocoliticaBT 1A isolates in order to evaluate their relatedness and pathogenic potential.ResultsA subset of 71 BT 1A strains, selected based on their varying LPS patterns, were subjected to detailed genetic analyses. The MLST on seven house-keeping genes (adk, argA, aroA, glnA, gyrB, thrA, trpE) conducted on 43 of the strains discriminated them into 39 MLST-types. By Bayesian analysis of the population structure (BAPS) the strains clustered conclusively into two distinct lineages, i.e. Genetic groups 1 and 2. The strains of Genetic group 1 were more closely related (97% similarity) to the pathogenic bio/serotype 4/O:3 strains than Genetic group 2 strains (95% similarity). Further comparison of the 16S rRNA genes of the BT 1A strains indicated that altogether 17 of the 71 strains belong to Genetic group 2. On the 16S rRNA analysis, these 17 strains were only 98% similar to the previously identified subspecies ofY. enterocolitica. The strains of Genetic group 2 were uniform in their pathogenecity-related properties: they lacked theystBgene, belonged to the same LPS subtype or were of rough type, were all resistant to the five tested yersiniophages, were largely resistant to serum complement and did not ferment fucose. The 54 strains in Genetic group 1 showed much more variation in these properties. The most commonly detected LPS types were similar to the LPS types of reference strains with serotypes O:6,30 and O:6,31 (37%), O:7,8 (19%) and O:5 (15%).ConclusionsThe results of the present study strengthen the assertion that strains classified asY. enterocoliticaBT 1A represent more than one subspecies. Especially the BT 1A strains in our Genetic group 2 commonly showed resistance to human serum complement killing, which may indicate pathogenic potential for these strains. However, their virulence mechanisms remain unknown.
The study of two barley Type I-like MADS-boxgenes as potential targets of epigenetic regulation during seed development
Authors: Kapazoglou Aliki , Engineer Cawas , Drosou Vicky , Kalloniati Chrysanthi , Tani Eleni , Tsaballa Aphrodite , Kouri Evangelia D , Ganopoulos Ioannis , Flemetakis Emmanouil , Tsaftaris Athanasios S 
Published: September 2012

Abstract

Background
MADS-box genes constitute a large family of transcription factors functioning as key regulators of many processes during plant vegetative and reproductive development. Type II MADS-box genes have been intensively investigated and are mostly involved in vegetative and flowering development. A growing number of studies of Type I MADS-box genes in Arabidopsis, have assigned crucial roles for these genes in gamete and seed development and have demonstrated that a number of Type I MADS-box genes are epigenetically regulated by DNA methylation and histone modifications. However, reports on agronomically important cereals such as barley and wheat are scarce.

Results
Here we report the identification and characterization of two Type I-like MADS-box genes, from barley (Hordeum vulgare), a monocot cereal crop of high agronomic importance. Protein sequence and phylogenetic analysis showed that the putative proteins are related to Type I MADS-box proteins, and classified them in a distinct cereal clade. Significant differences in gene expression among seed developmental stages and between barley cultivars with varying seed size were revealed for both genes. One of these genes was shown to be induced by the seed development- and stress-related hormones ABA and JA whereas in situ hybridizations localized the other gene to specific endosperm sub-compartments. The genomic organization of the latter has high conservation with the cereal Type I-like MADS-box homologues and the chromosomal position of both genes is close to markers associated with seed quality traits. DNA methylation differences are present in the upstream and downstream regulatory regions of the barley Type I-like MADS-box genes in two different developmental stages and in response to ABA treatment which may be associated with gene expression differences.

Conclusions
Two barley MADS-box genes were studied that are related to Type I MADS-box genes. Differential expression in different seed developmental stages as well as in barley cultivars with different seed size was evidenced for both genes. The two barley Type I MADS-box genes were found to be induced by ABA and JA. DNA methylation differences in different seed developmental stages and after exogenous application of ABA is suggestive of epigenetic regulation of gene expression. The study of barley Type I-like MADS-box genes extends our investigations of gene regulation during endosperm and seed development in a monocot crop like barley.
Association between stigma, depression and quality of life of people living with HIV/AIDS (PLHA) in South India – a community based cross sectional study
Authors: Charles Bimal , Jeyaseelan Lakshmanan , Pandian Arvind Kumar , Sam Asirvatham Edwin , Thenmozhi Mani , Jayaseelan Visalakshi 
Published: September 2012

Abstract

Background
India has around 2.27 million adults living with HIV/AIDS who face several challenges in the medical management of their disease. Stigma, discrimination and psychosocial issues are prevalent. The objective of the study was to determine the prevalence of severe stigma and to study the association between this, depression and the quality of life (QOL) of people living with HIV/AIDS (PLHA) in Tamil Nadu.

Methods
This was a community based cross sectional study carried out in seven districts of Tamil Nadu, India, among 400 PLHA in the year 2009. The following scales were used for stigma, depression and quality of life, Berger scale, Major Depression Inventory (MDI) scale and the WHO BREF scale. Both Stigma and QOL were classified as none, moderate or severe/poor based on the tertile cut off values of the scale scores. Depression was classified as none, mild, moderate and severe. Logistic regression analyses were performed to study the risk factors.

Results
Twenty seven per cent of PLHA had experienced severe forms of stigma. These were severe forms of personalized stigma (28.8%), negative self-image (30.3%), perceived public attitude (18.2%) and disclosure concerns (26%). PLHA experiencing severe depression were 12% and those experiencing poor quality of life were 34%. Poor QOL reported in the physical, psychological, social and environmental domains was 42.5%, 40%, 51.2% and 34% respectively. PLHA who had severe personalized stigma and negative self-image had 3.4 (1.6-7.0) and 2.1 (1.0-4.1) times higher risk of severe depression respectively (p < .001). PLHA who had severe depression had experienced 2.7(1.1-7.7) times significantly poorer QOL.

Conclusions
Severe forms of stigma were equivalently prevalent among all the categories of PLHA. However, PLHA who had experienced severe depression had only developed poor QOL. A high level of social support was associated with a high level of QOL.
Trends in overweight and obesity in Lebanon: evidence from two national cross-sectional surveys (1997 and 2009)
Authors: Nasreddine Lara , Naja Farah , Chamieh Marie Claire , Adra Nada , Sibai Abla-Mehio , Hwalla Nahla 
Published: September 2012

Abstract

Background
Even though the obesity epidemic continues to grow in various parts of the world, recent reports have highlighted disparities in obesity trends across countries. There is little empirical evidence on the development and growth of obesity in Lebanon and other countries of the Eastern Mediterranean Region. Acknowledging the need for effective obesity preventive measures and for accurate assessment of trends in the obesity epidemic, this study aims at examining and analyzing secular trends in the prevalence of overweight and obesity over a 12-year period in Lebanon.

Methods
Based on weight and height measurements obtained from two national cross-sectional surveys conducted in 1997 and 2009 on subjects 6 years of age and older, BMI was calculated and the prevalence of obesity was determined based on BMI for adults and BMI z-scores for children and adolescents, according to WHO criteria. Age -and sex- adjusted odds ratios for overweight and obesity were determined, with the 1997 year as the referent category. Annual rates of change in obesity prevalence per sex and age group were also calculated.

Results
The study samples included a total of 2004 subjects in the 1997 survey and 3636 in the 2009 survey. Compared to 1997, mean BMI values were significantly higher in 2009 among all age and sex groups, except for 6–9 year old children. Whereas the prevalence of overweight appeared stable over the study period in both 6–19 year old subjects (20.0% vs. 21.2%) and adults aged 20 years and above (37.0% vs. 36.8%), the prevalence of obesity increased significantly (7.3% vs. 10.9% in 6–19 year olds; 17.4% vs. 28.2% in adults), with the odds of obesity being 2 times higher in 2009 compared to 1997, in both age groups (OR = 1.96, 95% CI:1.29-2.97 and OR = 2.01, 95% CI: 1.67-2.43, respectively). The annual rates of change in obesity prevalence ranged between +4.1% in children and adolescents and +5.2% in adults.

Conclusion
The study’s findings highlight an alarming increase in obesity prevalence in the Lebanese population, over the 12-year study period, and alert to the importance of formulating policies and nutritional strategies to curb the obesity rise in the country.
Immunomodulatory and antitumour effects of abnormal Savda Munziq on S180 tumour-bearing mice
Authors: Aikemu Ainiwaer , Umar Anwar , Yusup Abdiryim , Upur Halmurat , Berké Bénédicte , Bégaud Bernard , Moore Nicholas 
Published: September 2012

Abstract

Background
Abnormal Savda Munziq (ASMq), a traditional uyghur medicine, has shown anti-tumour properties in vitro. This study attempts to confirm these effects in vivo and measure effects on the immune system.

Methods
Kunming mice transplanted with Sarcoma 180 cells were treated with ASMq (2–8 g/kg/day) by intra-gastric administration compared to model and cyclophosphamide (20 mg/kg/day). After the 14th day post tumour implant, thymus, liver, spleen and tumours were removed, weighed, and processed for histopathological analysis. Blood samples were also taken for haematological and biochemical analyses including TNF-α , IL-1 β and IL-2. Splenic lymphocyte function was measured with MTT; lymphocyte subpopulations were measured by flow cytometry.

Results
ASMq treated animals had reduced tumour volume compared to model and increased concentrations of TNF-α, IL-1β and IL-2 compared to untreated and to cyclophosphamide-treated animals. No histopathological alterations were observed. The absence of viable S180 cells and the presence of necrotic cells and granulation tissue were observed in tumour tissue of treated animals. The effect on T lymphocytes was unclear.

Conclusions
ASMq confirmed in vivo anti-tumour effects observed in vitro, which may be at least in part mediated by increased immune activity.