bluuebunny/crossref_metadata_2025_split huggingface dataset:
Doenças transmitidas por alimentos no Brasil: perfil epidemiológico de 2012 a 2021
Authors: Oliveira Samara Verena Barbosa de , Damasceno Lobo Patrícia Teixeira 
Published: July 2024

As Doenças Transmitidas por Alimentos (DTAs) tem sito alvo de muita discussão no âmbito da insegurança alimentar e tem representado um desafio para a saúde pública no Brasil. Várias infecções alimentares tem como causa principal a ingestão de alimentos ou bebidas contaminados por microrganismos, substâncias químicas ou outros agentes nocivos. Objetivou-se com esse estudo, analisar a situação epidemiológica dos surtos de Doenças Transmitidas por Alimentos no Brasil, notificadas ao SINAN em um período compreendido entre 2012 e 2021. Trata-se de um estudo descritivo, do tipo transversal, com abordagem quantitativa, no qual foram analisadas as ocorrências de surtos de DTAs no Brasil no período de 2012 a 2021 registrados pelo Sistema de Informação de Agravos de Notificação (SINAN). As análises foram baseadas no número de surtos de DTAs por ano de notificação, o número de pessoas hospitalizadas, doentes, número de óbitos, estado de abrangência, agentes etiológicos, critério de confirmação e o total de contaminados. Tendo em vista a saúde pública e os resultados apresentados, analisamos a necessidade uma atenção mais rigorosa na segurança alimentar no Brasil. Os dados da pesquisa revelam um alerta para os cuidados com as escolhas dos alimentos, principalmente para que sejam evitadas as doenças transmitidas por alimentos. Conclui-se que diversos fatores podem contribuir para a insegurança alimentar e tem se mostrado prevalente no Brasil o que pode esta relacionado a áreas de vulnerabilidade social e fragilidades na implantação de políticas públicas de saúde, bem como de saneamento básico para que seja realizado um controle efetivo das DTAs. Ademais, é válido destacar a necessidade de outros estudos que contribuam na discussão das DTAs possibilitando traçar diagnósticos assertivos das infecções para o controle e preveção das doenças alimentares no Brasil.
Maternal and Neonatal Outcomes with One Abnormal Value on 100g Three Hour Glucose Tolerance Test in Pregnancy
Authors: McDermott Eliza , Jois Madhuri , Adam Kailynn , Holthaus Emily , Wiley Lina , Lynn Mary 
Published: July 2024

Purpose: The primary objective of this study was to compare pregnancy outcomes for patients with no elevated glucose values, one elevated glucose value, and 2 or more elevated glucose values on the 3-hour glucose tolerance test (GTT). Methods: This was a retrospective chart review of obstetric patients seen by residents and attending physicians at a single institution from 2015 to 2020 who were required to complete a 3-hour glucose tolerance test (GTT). Data extracted from the maternal chart included demographic information, BMI, route of delivery, presence of preeclampsia, chorioamnionitis, shoulder dystocia and preterm labor. Data extracted from the neonatal chart included blood glucose level after birth, birth weight, Apgar scores, and if NICU admission was required. Continuous data were analyzed using one-way ANOVA to compare the 3 groups, followed by post-hoc Tukey HSD to compare the 1 abnormal value group to the control group. Dichotomous data were analyzed using Chi square tests. Logistic regression was performed using shoulder dystocia as the outcome. Results: Patients with two or more elevated GTT values had higher age and BMI and were more likely to be prescribed diabetic medications compared to those with normal or one elevated value. They were also more likely to deliver at an earlier gestational age. Patients with one elevated GTT value experienced a statistically significant higher chance of shoulder dystocia compared to patients with all normal GTT results (OR 2.34; 95% CI 1.05, 5.20). Patients with two or more elevated values were more likely to have preeclampsia and a neonate requiring NICU admission. There were no differences in cesarean delivery rate, hemorrhage or chorioamnionitis between the groups. Conclusions: Patients with one elevated GTT value are a special subset of patients who do not meet criteria for gestational diabetes, yet do not have normal glucose testing results. We hypothesize that this group is at higher risk of shoulder dystocia because these patients may have hyperglycemia but often do not receive the same type of monitoring, dietary education, medication initiation and induction timing as patients who meet criteria for gestational diabetes.
Cannabis Hyperemesis Syndrome: An Underrecognized Cause of Nausea and Vomiting in Pregnancy
Authors: Forsythe Riley Elizabeth , Vircks Julie , Madrigal Megan , Florio Karen 
Published: July 2024

Introduction: Cannabis Hyperemesis Syndrome (CHS) is characterized by refractory and recurrent nausea and vomiting in birthing people with chronic cannabis use and is emerging as an increasingly common diagnosis in patients who present to the emergency department. The objective of this retrospective case series was to describe presentation, management and outcomes of CHS during pregnancy. Methods: Patients were identified by the investigator at two tertiary care centers in Kansas City from January 2019 to October 2021. Patients were included if (1) intrauterine pregnancy (2) refractory and recurrent nausea and vomiting without acute cause, and (3) documented chronic cannabis use which preceded symptom onset were noted. The study was approved by the UMKC IRB (#308059). Results: Twelve patients were identified who met inclusion criteria, ranging in age from 17 to 32 years (mean 23.2 ± 4.5). Eleven patients reported daily cannabis use. The mean number of emergency department visits during pregnancy for nausea and vomiting was 8.9 (± 7.1). Patients presented at a wide range of gestational ages, between 4 and 37 weeks (mean 19.6 ± 9.8). Compulsive hot water bathing for symptom relief was documented in 33% of cases (4 of 12). The rate of fetal growth restriction in this series was 44% (4 of 9). Despite counseling, only one patient successfully discontinued cannabis use. Conclusions: CHS should be considered in the differential diagnosis of nausea and vomiting in pregnancy. Patients who meet criteria should be counseled about cannabis cessation as part of treatment recommendations.
Does Pharmacologic Treatment of Depression Alter Prenatal Care Compliance in Substance Use Disorder
Authors: Parilla Barbara , Patel Neil , Stromberg Arnold , Hawk Gregory , Cockerham Cynthia , O'Brien John 
Published: July 2024

Objective: To evaluate whether antidepressant utilization alters prenatal compliance in patients with Substance Use Disorder (SUD) enrolled in a multidisciplinary treatment program. Methods: Patients in a cohort study of women enrolled in an SUD program between 2015 and 2022 were eligible. Patients with the co-morbidity of depression at the initial behavioral health assessment were selected. Use of antidepressant medications was recorded at enrollment and during prenatal visits. Prenatal care compliance was the primary outcome. Edinburgh scores and neonatal outcomes were secondary outcomes. Fisher’s Exact test was used in analysis of variables. Results: 240 of 456 (52%) patients had a history of depression. 40 of 240 (17%) were on antidepressants at enrollment versus 7 of 240 (3%) were started on antidepressants during pregnancy. 20 patients on antidepressants out of 47 (61%) having an Edinburgh score ≥12 at enrollment while 54 patients (62%) of the 193 women not treated scored ≥12, P=1.0. SSRIs were the most commonly used drugs (85%). Demographic data was similar between groups. A GAD 7 scores ≥10 was common in patients on medication (47%, n=15), and untreated, (54%, n=61), P=.21. The AAS score was positive for abuse in 27 women on medication (57%) versus 113 (59%) untreated, P=1.0. Patients treated with antidepressants were more commonly on Medication-Assisted Treatment (MAT) at enrollment, 14/47 (32%) vs untreated 23/193 (13%), P=.005. Prenatal visit compliance did not differ between the groups of treated (48% ± 27%) vs untreated (50% ± 28%), P=0.65. Gestational age at delivery, and birthweight did not differ between those treated and not treated with antidepressants. NAS treatment 46% (n=21) vs 44% (n=82), P=.87; and length of hospital stay 14.7 ± 12.0 vs 14.8 ± 20.4, P=.99, were similar. Conclusions: Pregnant patients enrolling in substance use program have a high rate of co-existing depression, anxiety and abuse with a minority of patients on antidepressants despite similar risk profiles. Patients on antidepressants were more commonly on MAT on enrollment. Early treatment was not associated with worsening rates of prenatal care attendance, preterm birth, NAS or neonatal hospitalization. Increased frequency of treatment appears warranted in this population based on elevated Edinburgh scores.
Effectiveness of a Hysteroscopic Tissue Removal System Device for Hysteroscopic Myomectomy on Patients’ Quality of Life: A Randomized Clinical Trial
Authors: Tam Teresa , Juarez Lourdes 
Published: July 2024

Background: This is the first prospective randomized analysis comparing outcomes of medical therapy versus hysteroscopic myomectomy using the TruClearTM hysteroscopic tissue removal system to treat heavy menstrual bleeding from sub-mucosal leiomyoma(s). Objective: To evaluate the quality of life in patients treated for submucosal leiomyomas after hysteroscopy myomectomy compared to medical therapy. Study Design: Setting: private practice and community-based hospital; subjects: female patients with symptomatic submucosal leiomyomas from 2014-2017. A total of 69 patients enrolled, with 47 completed. Statistical analysis used: randomized clinical trial. Each patient was randomized to oral contraceptive pills/progesterone releasing intrauterine device or hysteroscopic myomectomy. Each patient was to complete the Uterine Fibroid Symptom and Health-related Quality of Life (UFS-QOL) questionnaire at baseline, one month, three months, and greater than or equal to six months after treatment. Primary outcome was the health-related quality of life (HR-QOL), as reflected from UFS-QOL scores. Contrasts were constructed from a linear mixed-effects model to compare the two treatment groups for changes from baseline in UFS-QOL scores. Results: UFS-QOL scores were similar at baseline between the two treatment groups. There was an overall improvement in all UFS-QOL scores within each group. Higher improvement scores were noted in the surgical group compared to the medical group for almost all UFS-QOL scores. At ≥6 months, in comparison to the medically managed patients, the most considerable score improvements for the surgical group were reported in HR-QOL concern, activities, self-consciousness and symptom severity scores having mean change scores (95% CIs) of 35.3 (22.3 – 48.2), 28.9 (16.3 – 41.5), 28.6 (15.0 – 42.1), and 32.2 (21.5 – 43.0), respectively. Conclusion: Patients with submucosal leiomyomas who received medical or surgical treatment reported similar improvement in overall HR-QOL scores.
Leiomyomatosis: A Rare Case of Mistaken Identity
Authors: Tam Teresa , Groves Yuan Y. , Lizon Christopher 
Published: July 2024

Abstract: Diffuse uterine leiomyomatosis (DUL) is a rare benign uterine pathology that is often misdiagnosed as uterine leiomyomas. We present a case of a woman with abnormal uterine bleeding treated with multiple medical therapies without symptomatic relief. She underwent two surgeries, almost a year apart, with the histopathologic diagnosis of leiomyomas. After numerous failed attempts at medical and surgical treatments, the patient requested definitive surgery and underwent a robotic-assisted laparoscopic hysterectomy. Histopathologic analysis of the entire uterine specimen confirmed diffuse uterine leiomyomatosis. Case Report: A 31-year-old female was referred to our office with a history of abnormal uterine bleeding and heavy menstrual bleeding who failed hormonal therapies. Levonorgestrel-releasing intrauterine devices were inserted at two different times and were expelled due to heavy menses. Pelvic magnetic resonance imaging reported leiomyomas. The patient underwent hysteroscopy and a robotic-assisted myomectomy. Pathology revealed leiomyomas. Seven months after her first surgery, her bleeding recurred, and the patient became severely anemic, requiring hospitalization and transfusion of 2 units of packed RBCs. Over a year later, the patient underwent a second hysteroscopic and robotic myomectomy after failed medical therapies of tranexamic acid, progesterone medication, and gonadotropin-releasing hormone antagonist with minimal symptom relief. Her quality of life suffered tremendously due to ongoing AUB-HMB. After seven months, the patient requested definitive surgical therapy and underwent a robotic-assisted laparoscopic hysterectomy. Pathology reported diffuse uterine leiomyomatosis. Diffuse uterine leiomyomatosis is a rare benign uterine pathology that is often misdiagnosed as uterine leiomyomas. Early diagnosis of DUL is challenging and often inconclusive. Less than 50 diffuse uterine leiomyomatosis cases have been reported in the literature. The myometrium in DUL is almost entirely replaced by numerous ill-defined benign smooth muscle tumors. MRI offers mapping of the size, site, and distribution of leiomyomas, but findings are difficult to differentiate from DUL. The pathophysiology of DUL development remains poorly understood, with patients frequently complaining of abnormal uterine bleeding, heavy menstrual bleeding, fertility issues, and dysmenorrhea. DUL is often misdiagnosed as leiomyomas or adenomyosis clinically, given the similarity in manifestations. Leiomyomatosis is histologically characterized by the proliferation of smooth muscle cells forming fascicles and nodules, which blend with normal myometrium tissue. Hysterectomy is the definitive treatment of DUL, with this case report demonstrating the close similarity between the two.
Case Report of Lipomyoma
Authors: Diaz Lucero , Tam Teresa 
Published: July 2024

Report: Uterine lipoleiomyoma are rare forms of leiomyomas that are often only described in literature as case reports. Lipoleiomyomas could increase in size despite menopause and most commonly occur in postmenopausal women with an incidence rate of 0.03% to 0.2% Clinical symptoms of lipoleiomyoma are very similar to leiomyoma. Radiologic imaging can aid in the diagnosis of lipoleiomyoma with smooth muscle confined to the tumor periphery. In our case, we describe a 53y/o G0P0 perimenopausal patient who complained of abnormal uterine bleeding with irregular menses, urinary retention and difficulty completely emptying her bladder due to the large mass compressing her bladder. She was diagnosed with a large 8.8 cm hyperechoic lesion with internal vascularity arising from the central uterus/ endometrium. Radiology recommended a pelvic MRI for further differentiation of mass. Office hysteroscopy with endometrial biopsy was performed. Pathology confirmed limited inactive endometrium, benign endometrial surface epithelium. The patient requested a hysterectomy through a minimally invasive gynecologic surgery approach. A pelvic MRI was performed that revealed a large, round, circumscribed mass measuring 7.3 X 7.2 X 7.5 cm favoring to represent an intramural lipoleiomyoma. The patient had a robotic assisted laparoscopic hysterectomy which was uncomplicated. Final histopathologic diagnosis was uterine lipomyoma. As benign masses, management for lipoleiomyoma are guided by symptoms, fertility preservation desires, and whether or not a patient is a candidate for surgical intervention. Given the rarity of these cases, the histogenesis is still relatively unknown although various theories exist such as differentiation of embryonic fat cells, metaplastic changes of existing cells into fat cells, and pluripotent cell migration. Although there was not evidence of malignancy in our case report, certain literature has suggested the presence of coexisting malignancies and in an even rarer occasion the presence of liposarcoma from a lipoleiomyoma. More information is needed on these rare cases in order to further lead management and any recommendations regarding cancer screening on top of age related recommendations already in place.
On the safety of life support facilities in the activities of law enforcement agencies
Authors: Борбат А.В. 
Published: July 2024

В статье рассмотрены вопросы, связанные с обеспечением безопасности объектов жизнеобеспечения в деятельности правоохранительных органов России. Автором приводятся статистические сведения о количестве зарегистрированных преступлений, предусмотренных ст. 215.2 УК РФ, анализируется тенденция их развития. Автором приводятся конкретные формы деятельности органов внутренних дел Российской Федерации, позволяющие повысить безопасность рассматриваемых объектов. В статье говорится о необходимости создания обособленных специальных подразделений, деятельность которых будет направлена на предупреждение, раскрытие и расследование преступлений, совершенных в отношении объектов жизнеобеспечения.
The article discusses issues related to ensuring the safety of life support facilities in the activities of law enforcement agencies in Russia. The author provides statistical information on the number of registered crimes under Article 215.2 of the Criminal Code of the Russian Federation, analyzes the trend of their development. The author provides specific forms of activity of the internal affairs bodies of the Russian Federation, which make it possible to increase the safety of the objects under consideration. The article considers the need to create separate special units whose activities will be aimed at preventing, uncovering and investigating crimes committed against life support facilities.
The use of unmanned aerial vehicles to prevent environmental crime in the Khanty-Mansiysk Autonomous Okrug – Yugra
Authors: Шапошников А.С. 
Published: July 2024

В статье анализируется уровень латентности экологической преступности, определяются факторы, его обуславливающие: особенности территории, на которой совершаются преступления, и неэффективность действующей системы мер по предупреждению экологической преступности (непосредственное обнаружение). На примере Ханты-Мансийского автономного округа – Югры как региона, наиболее подверженного негативному антропогенному воздействию и загрязнению окружающей среды нефтяными продуктами, устанавливается, что добровольное сообщение недропользователями об инцидентах на трубопроводе не является достоверным способом фиксации нарушения состояния природной среды. В связи с неэффективностью непосредственного обнаружения фактов совершения экологических преступлений предлагается внедрить в деятельность государственных органов беспилотные летательные аппараты, которые позволяют охватить в сравнении с пешим способом намного бо́льшую территорию и зафиксировать правонарушения, установление которых затруднительно в процессе традиционного патрулирования, осуществляемого на подконтрольной территории.
The article analyzes the level of latency of environmental crime, determines the factors that cause it: the characteristics of the territory where crimes are committed, and the inefficiency of the current system of measures to prevent environmental crime (direct detection). Using the example of the Khanty-Mansiysk Autonomous Okrug – Yugra as the region most susceptible to negative anthropogenic impact and environmental pollution by oil products, it is established that voluntary reporting by subsurface users about incidents on the pipeline is not a reliable way to fix violations of the state of the natural environment. Due to the ineffectiveness of direct detection of the facts of environmental crimes, it is proposed to introduce unmanned aerial vehicles into the activities of state bodies, which make it possible to cover a much larger territory in comparison with walking and record offenses, the establishment of which is difficult in the process of traditional patrolling carried out in a controlled territory.
Analisis Mata Kuliah di IPB University Berdasarkan Tujuan Pembangunan Berkelanjutan (SDGs)
Authors: Mardiana Rina 
Published: July 2024

Penelitian ini bertujuan menganalisis sebaran mata kuliah di IPB University berdasarkan Tujuan Pembangunan Berkelanjutan (Sustainable Development Goals, SDGs) dan mengidentifikasi kontribusi mata kuliah yang tersebar di setiap fakultas terhadap pencapaian SDGs. Metodologi yang digunakan meliputi pengumpulan data dari database internal IPB yang mencakup 5450 mata kuliah. Data tersebut kemudian diolah berdasarkan kata kunci SDGs Esevier 2023 melalui filter kata negasi, penerjemahan ke Bahasa Indonesia, dan penghapusan duplikat. Analisis dilakukan dengan mengkategorisasi mata kuliah berdasarkan relevansinya dengan masing-masing dari 17 SDGs. Hasil utama menunjukkan bahwa SDG 4 "Pendidikan Berkualitas" memiliki sebaran tertinggi dengan 5198 mata kuliah, sementara SDG 10 "Mengurangi Ketimpangan" memiliki sebaran terendah dengan 1688 mata kuliah. Temuan ini mengindikasikan komitmen IPB terhadap kualitas pendidikan, namun memerlukan peningkatan dalam pengurangan ketimpangan.
The Nawawi al-Bantani's Hadith Thought in Tanqih al-Qaul al-Hatsits fi Syarh Lubab al-Hadits
Authors: 'Azima Muhammad Fauzhan , Nur Zunaidi 
Published: July 2024

Nawawi al-Bantani is known as a great scholar from Banten, on the west coast of Java who has expertise in various Islamic disciplines, including hadith science. This paper explores Nawawi al-Bantani's thoughts in the field of hadith science as contained in his book, namely the book Tanqih al-Qaul al-Hatsits fi Syarh Lubab al-Hadits. The book Tanqih al-Qaul is a book written by al-Bantani to lecture on the content of the book Lubab al-Hadits by as-Suyuthi. Although it is a type of syarah book, the book of Tanqih al-Qaul not only contains lectures on the hadiths in the book Lubab al-Hadits, but also contains al-Bantani's own thoughts as the author of the book Tanqih al-Qaul, in the field of hadith science. The research method used in this paper is a qualitative method with the type of library research. Meanwhile, as a data analysis knife, an analytical descriptive method is used with the type of analysis used, namely critical analysis. The results of the study show that the thinking of al-Bantani hadith is: the ability to use dha'if hadith in terms of fadhail al-a'mal and not in the field of law and creed, the importance of sanad for the validity of hadith narration, as well as the explanation of the definitions of basic terms in hadith science which include shahih, isnad, sanad, and matan. Al-Bantani's thinking in the field of hadith science also shows his independence from as-Suyuthi. This means that al-Bantani not only re-copied all the thoughts of as-Suyuthi in the book Lubab al-Hadits, but also gave rise to his own thoughts.
Artificial Intelligence (AI) and Physiology
Authors: Sarbadhikari Suptendra Nath 
Published: July 2024

Artificial Intelligence (AI) is threatening to pervade all domains and Physiology or Medicine is no exception. There are two ways that we can look at it: (i) AI applications being used to understand and modify physiological functions, and (ii) Understanding (neuro)physiology well to apply the principles for improving algorithms that power AI applications. Across multiple biological systems in human physiology, AI can integrate with traditional diagnostic tests in medicine, and AI can sometimes determine additional findings missed by traditional diagnostic tests. Many intelligent healthcare systems are now being used for automated and real-time patient monitoring. The obvious question is whether automated AI applications will replace human physiologists or not. The answer is that physiologists using AI will replace physiologists not using AI, since computer plus brain is greater than either alone. Also, we need to be concerned about the ethical issues related to the use of AI in physiology and medicine.