bluuebunny/crossref_metadata_2025_split huggingface dataset:
A historical overview of experimental hydrology in China
Authors: Nan Yi , Chen Changchun , Zhao Ying , Tian Fuqiang , McDonnell Jeffrey 
Published: July 2024

AbstractThe history of experimental hydrology in China is important but poorly documented. Here we review 94 papers (86 of these in Chinese) from the CNKI and Web of Science websites to chronicle the history of experimental studies in China before 2000. Professor Wei‐Zu Gu—the focus of this Special Issue—factors heavily into this history. Perhaps more than any country, the experimental hydrology history of China is influenced by socioeconomic development and political change. Our analysis shows 4 main periods of development associated with (1) an early development stage before 1949, the founding year of People's Republic of China (PRC), (2) an initial period of rapid transition in experimental studies in China (1949–1965), (3) a struggling and recovering stage for during and shortly after the Cultural Revolution, from 1965 to 1978, and (4) significant progress associated with new policies for reform and opening up in China from 1978 to 2000, that included contributions of Wei‐Zu Gu and other scientists. In terms of experimental hydrological findings, two notable contributions are a mathematical description of saturation overland flow derived from streamflow and precipitation data and calculated water storage deficit in the unsaturated zone by Zhao and Zhuang (1963), several years before its process‐based ‘discovery’ in the USA (and elsewhere) and the ‘interface runoff generation law’ of Yu (1985) which was ahead of its time in understanding linking the notion of the commonality of all runoff forms. In terms of model development stemming from experimental studies, the development of the Xinanjiang Model of Zhao (1980) was a significant achievement, later partly adopted into the VIC model in the USA and the ARNO model in Europe. Finally, the Hydrohill catchment developed by Wei‐Zu Gu led the way for the rapid rise in process studies and internationalization of experimental hydrology in China. Overall, the experimental hydrological studies from 1949 to 2000 had a strong engineering focus, with many links to water conservation construction and management.
Fill‐spill‐merge terrain analysis reveals topographical controls on Canadian river runoff
Authors: Wagle Nimisha , Smith Laurence C. 
Published: July 2024

AbstractDigital Elevation Models (DEMs) are a crucial tool for watershed analysis, offering valuable insights into landscape‐scale hydrology. Traditional watershed delineations are derived by filling a DEM to force flow paths through topographic depressions, thus creating a continuous drainage network throughout the domain. However, this approach is challenged in landscapes with abundant real‐world depression storage, intermittently flowing stream channels, and internally drained lake basin (endorheic basin) such as the Canadian Shield (CS). The CS landscape is characterized by “fill‐and‐spill” surface water hydrology, with runoff flow paths controlled by bedrock sills and rocky cascades that overtop when water levels are high but cease flowing when water levels are low. To better represent these intermittent drainage networks, we apply a non‐traditional, less‐aggressive DEM filling model (Fill‐Spill‐Merge or FSM) to a continental‐scale DEM (MERIT) all of Canada. To ensure adequate filling of DEM noise while also preserving real‐world topographic depressions, we propose a climatic method to initialize a key FSM parameter (“runoff depth”) that calibrates observed discharges from 1690 Environment and Climate Change Canada (ECCC) river gauges with climate model P‐ET (precipitation minus evapotranspiration) data. Our application of FSM to all 1690 gauged watersheds identifies 916 significant topographical control points controlling >20% and/or 1000 km2 of their respective areas. The Geikie, Snare, Kazan, Tazin, and Seal rivers may be particularly affected, with impacted watershed areas ranging from 12% to 64%. Extending this approach to ungauged parts of the CS reveals an additional 635 significant topographical control points. Ensemble climate model projections suggest that around 10% of these control points are currently dry but will become active by 2100. This research explicitly determines how CS watersheds are affected by fill‐and‐spill hydrology, and demonstrates the importance of accurate terrain modelling for delineating surface water flow paths in depressional landscapes.
Microplastics from petroleum-based plastics and their effects: A systematic literature review and science mapping of global bioplastics production
Authors: Mutmainna Inayatul , Gareso Paulus Lobo , Suryani Sri , Tahir Dahlang 
Published: July 2024

Abstract
The use of bioplastics is a new strategy for reducing microplastic (MP) waste caused by petroleum-based plastics. This problem has received increased attention worldwide, leading to the development of large-scale bioplastic plants. The large amount of MPs in aquatic and terrestrial environments and the atmosphere has raised global concern. This article delves into the profound environmental impact of the increasing use of petroleum-based plastics, which contribute significantly to plastic waste and, as a consequence, to the increase in MPs. We conducted a comprehensive analysis to identify countries that are at the forefront of efforts to produce bioplastics to reduce MP pollution. In this article, we explain the development, degradation processes, and research trends of bioplastics derived from biological materials such as starch, chitin, chitosan, and polylactic acid (PLA). The findings pinpoint the top 10 countries demonstrating a strong commitment to reducing MP pollution through bioplastics. These nations included the United States, China, Spain, Canada, Italy, India, the United Kingdom, Malaysia, Belgium, and the Netherlands. This study underscores the technical and economic obstacles to large-scale bioplastic production. Integr Environ Assess Manag 2024;20:1892–1911. © 2024 SETAC
Key Points
Microplastics (MP) have caused concern due to their environmental effects, potential to release plastic monomers, affinity for chemical interactions, and potential to enter aquaculture and fishery production. The findings pinpoint the top 10 countries demonstrating a strong commitment to reducing MP pollution by replacing petroleum-based plastics with bioplastics. Using bibliometric techniques, we mapped and identified the countries that were most actively engaged in shifting to bioplastic production during the period 2001–2021. This article focuses on starch-based bioplastics used primarily in food packaging, increasing their mechanical properties by adding fibers, and extending the shelf life of food with antibacterial nanoparticles.
Uterus transplantation: A scoping review focused on obstetric outcomes
Authors: Barragan‐Wolff Megan , Espinosa‐Cervantes Martha S. , Acevedo‐Gallegos Sandra , Rodriguez‐Sibaja Maria J. , Lumbreras‐Marquez Mario I. , Ito‐Esparza Maria J. 
Published: July 2024

AbstractBackgroundCongenital uterine anomalies include a wide diversity of uterine malformations that can compromise reproductive potential. Uterus transplantation (UTx) proposes an innovative treatment for absolute uterine factor infertility; however, there is a lack of standardized protocols to guide clinical management among this population.ObjectivesTo describe recipient and donor characteristics and obstetric outcomes in patients undergoing UTx.Search StrategyWe performed a literature search using the PubMed database to retrieve available scientific articles. We analyzed the references of included articles to assess additional articles that could be eligible to be included in the review. Likewise, we identified further studies using other methods, including Google Scholar.Selection CriteriaTitles and abstracts were screened in duplicate to select original reports with information available for the outcomes of interest.Data Collection and AnalysisThis review assessed the advantages and disadvantages of the techniques used, patient characteristics, obstetric and non‐obstetric complications, functional duration of the organ, and neonatal outcomes.Main ResultsAmong the 36 reports included in this review we found 55 pregnancies and 38 live births following UTx and a higher success rate for in vivo uterine donations. The most common obstetric complications reported included miscarriage, pre‐eclampsia, and gestational hypertension. The most common non‐obstetric complications reported include episodes of rejection, acute kidney injury, anemia, and cholestasis. Living donors required a comprehensive preoperative workup, decreasing organ rejection, infection, and vascular complications.ConclusionsMore studies are needed to standardize the UTx procedure and improve obstetric, fetal, and neonatal outcomes. Further understanding of which recipient and donor characteristics minimize complications will significantly decrease the risk of adverse outcomes.
Urinary tract fungal ball in a single kidney after total nephroureterocystectomy
Authors: Nakano Yoshinori , Sekino Yohei , Takemoto Kenshiro , Ueno Takeshi , Fujii Shogo , Kitano Hiroyuki , Hieda Keisuke , Ohara Shinya , Hinata Nobuyuki 
Published: July 2024

IntroductionFungal balls in the urinary tract are rare but dangerous complications of candiduria. Here, we report a case of a urinary tract fungal ball in a single kidney after total nephroureterocystectomy.Case presentationThe patient was an 80‐year‐old male. He had a history of pyelonephritis, and his ureteral stent was regularly replaced. He was admitted to the hospital with a chief complaint of urinary tract obstruction, and a 50‐mm‐sized mass was found within the renal pelvis. Because the ureteral stent frequently became obstructed, the mass was removed percutaneously. Candida albicans was detected on the tissue culture results, and the mass was diagnosed as a fungal ball.ConclusionAppropriate urinary drainage methods for fungal balls vary among patients, and it is important to select an appropriate method based on the accumulated number of cases.
A Multi‐Fusion Residual Attention U‐Net Using Temporal Information for Segmentation of Left Ventricular Structures in 2D Echocardiographic Videos
Authors: Wang Kai , Hachiya Hirotaka , Wu Haiyuan 
Published: July 2024

ABSTRACTThe interpretation of cardiac function using echocardiography requires a high level of diagnostic proficiency and years of experience. This study proposes a multi‐fusion residual attention U‐Net, MURAU‐Net, to construct automatic segmentation for evaluating cardiac function from echocardiographic video. MURAU‐Net has two benefits: (1) Multi‐fusion network to strengthen the links between spatial features. (2) Inter‐frame links can be established to augment the temporal coherence of sequential image data, thereby enhancing its continuity. To evaluate the effectiveness of the proposed method, we performed nine‐fold cross‐validation using CAMUS dataset. Among state‐of‐the‐art methods, MURAU‐Net achieves highly competitive score, for example, Dice similarity of 0.952 (ED phase) and 0.931 (ES phase) in , 0.966 (ED phase) and 0.957 (ES phase) in , and 0.901 (ED phase) and 0.917 (ES phase) in , respectively. It also achieved the Dice similarity of 0.9313 in the EchoNet‐Dynamic dataset for the overall left ventricle segmentation. In addition, we show MURAU‐Net can accurately segment multiclass cardiac ultrasound videos and output the animation of segmentation results using the original two‐chamber cardiac ultrasound dataset MUCO.
Nonclinical safety and immunogenicity assessment of a combined DTacP vaccine in animal models
Authors: Li Shihui , Fu Hui , Yu Shouzhi , Zhao Yuxiu , Liu Ting , Wang Ling , Zhang Na , Wang Wei , Yang Baifeng , He Peng , Guo Yancen , Qiu Shaoting , Zhang Yuntao 
Published: July 2024

AbstractThe (diphtheria, tetanus, and pertussis [acellular, component] [DTacP]) vaccine is a combined vaccine designed to prevent three potentially fatal diseases including pertussis, tetanus, and diphtheria in both children and adults. We utilized advanced technology to develop a novel DTacP vaccine that was previously unavailable in China. The nonclinical studies were performed to evaluate the immunogenicity, potential toxicity, and local tolerance of the vaccine in animal models. In the immunogenicity study, three batches of the vaccine were intraperitoneally administered to National Institutes of Health (NIH) mice, resulting in 100% seropositivity for all three batches. Additionally, antibody levels notably increased as the immunization dosage increased. In acute toxicity study, no mortality was observed among the animals during the 14‐day observation period, and no abnormalities in clinical signs were reported. Active systemic anaphylaxis assessment in guinea pigs showed no evidence of serious allergic reactions in the vaccine groups. In the repeat‐dose toxicity study, where five intramuscular doses were administered every 2 weeks, gross autopsy and histopathological examination revealed no vaccine‐related systemic pathological changes in rats, with dose site irritant reactions mostly recovered at the end of recovery period. In conclusion, the vaccine demonstrated good local and systemic tolerance, supporting its clinical development.
Analyst forecast revision consistency and reversal: Evidence of stock market efficiency
Authors: Chen Lin , Nie Dongfang , Shi Yuan , Zhang Yinghong 
Published: July 2024

AbstractThis study reexamines the information content and market price discovery associated with individual analysts' earnings forecast revisions. We refine the definition of high‐innovation revisions as high‐innovation consistent forecast revisions and high‐innovation reversal forecast revisions. Cross‐sectional analysis shows that high‐innovation reversal good (bad) news revisions, although having larger forecast changes, cause fewer upward (downward) post‐revision price shifts than high‐innovation consistent good (bad) news revisions. We also find that the market can distinguish which group of analysts provides more useful information about firms’ true value, but it takes some time for the market to digest this useful information.
Ab initio exploration of low‐lying electronic states of linear and bent MNX+ (M = Ca, Sr, Ba, Ra; X = O, S, Se, Te, Po) and their origins
Authors: Ariyarathna Isuru R. 
Published: July 2024

AbstractHigh‐level multireference and coupled cluster quantum calculations were employed to analyze low‐lying electronic states of linear‐MNX+ and side‐bonded‐M[NX]+ (M = Ca, Sr, Ba, Ra; X = O, S, Se, Te, Po) species. Their full potential energy curves (PECs), dissociation energies (Des), geometric parameters, excitation energies (Tes), and harmonic vibrational frequencies (ωes) are reported. The first three chemically bound electronic states of MNX+ and M[NX]+ are 3∑−, 1Δ, 1∑+ and 3A″, 1A′, 1A″, respectively. The 3∑−, 1Δ, 1∑+ of MNX+ originate from the M+(2D) + NX(2Π) fragments, whereas the 3A″, 1A′, 1A″ states of M[NX]+ dissociate to M+(2S) + NX(2Π) as a result of avoided crossings. The MNX+ and M[NX]+ are real minima on the potential energy surface and their interconversions are possible. The M2+NX−/M2+[NX]− ionic structure is an accurate representation for their low‐lying electronic states. The Des of MNX+ species were found to depend on the dipole moment (μ) of the corresponding NX ligands and a linear relationship between these two parameters was observed.
An improved DIIS method using a versatile residual matrix to accelerate SCF starting from a crude guess
Authors: Hu Linping , Sarwono Yanoar Pribadi , Ding Yonglong , He Fang , Zhang Rui‐Qin 
Published: July 2024

AbstractThe minimization of the commutator of the Fock and density matrices as the error matrix in the direct inversion of the iterative subspace (CDIIS) developed by Pulay is a powerful self‐consistent field (SCF) acceleration technique for the construction of optimum Fock matrix, if initiated with a fair initial guess. In this work, we present an alternative minimized error matrix to the commutator in the CDIIS, namely the residual or the gradient of the energy‐functional for a Slater determinant subject to the orthonormality constraints among orbitals, representing the search for a newly improved Fock matrix in the direction of the residual in the direct inversion of the iterative subspace (RDIIS). Implemented in the computational chemistry package GAMESS, the RDIIS is compared with the standard CDIIS and the second order SCF orbital optimization (SOSCF) for tested molecules started with a crude guess. As a result, the RDIIS stably and efficiently performs the SCF convergence acceleration. Furthermore, the RDIIS is considerably independent on the subspace size with the concentrated linear coefficients accounting proportionally for the Fock matrices close to the current iteration.
Identification and characterization of RAC1‐related immune and prognostic subtypes of hepatocellular carcinoma
Authors: Wang Wei , Xia Hui , Feng Pei , Dai Bin 
Published: July 2024

AbstractBackgroundHepatocellular carcinoma (HCC) is a malignant tumor with significant variability in prognosis among patients. Ras‐related C3 botulinum toxin substrate 1 (RAC1) is a key focus in the area of cancer research. However, the molecular mechanisms of RAC1 in HCC remain incompletely elucidated.Materials and methodsIn this study, bioinformatics analysis was used, and public databases were used to obtain information about HCC cases. The samples were categorized into two groups of high and low expression based on the expression level of RAC1 gene. The limma package was used to calculate the differentially expressed genes between the two groups, and univariate Cox regression analysis was used to screen the prognostic related factors. Consensus clustering analysis was performed using the ConsensusClusterPlus package to identify molecular subtypes of HCC patients. Immune cell infiltration and ESTIMATE scores were assessed using the single sample gene set enrichment analysis and ESTIMATE algorithms. The sensitivity of different isoforms to chemotherapeutic agents was predicted by the oncoPredict package. Finally, we also performed cell function experiments to validate the biological role of RAC1 in vitro. Initially, we classified patients into high and low expression groups based on RAC1 gene expression levels and identified 195 up‐regulated genes and 107 down‐regulated genes. Through univariate Cox regression analysis, we screened out 169 prognosis‐related factors. Furthermore, HCC patients were categorized into two subtypes. Subsequently, Kaplan–Meier survival curves showed that there was a significant difference in prognosis between the two molecular subtypes. Further analysis indicated substantial differences in gene expression levels and TIDE scores between two molecular subtypes. Moreover, these two subtypes exhibited varying sensitivity to chemotherapy drugs, as evidenced by differences in IC50 values. In addition, we found that the silence of RAC1 could effectively inhibit the migration and invasion of HCC cells in vitro.ConclusionThis study sheds light on the molecular intricacies of RAC1 in HCC and identifies patient populations that may benefit from immunotherapeutic interventions, with potential implications for tailored treatment strategies.
“Fast but not so furious”: A condensed step‐up dosing schedule of teclistamab for relapsed/refractory multiple myeloma
Authors: Graf Kevin C. , Davis James A , Cendagorta Alyssa , Granger Katelynn , Gaffney Kelly J. , Green Kimberly , Hess Brian T , Hashmi Hamza 
Published: July 2024

AbstractTeclistamab is a B‐cell maturation antigen (BCMA)‐directed bispecific T‐cell engager approved for relapsed‐refractory multiple myeloma (RRMM). Cytokine release syndrome (CRS) and Immune effector cell‐associated neurotoxicity syndrome (ICANS) are well‐documented treatment ‐related adverse events of teclistamab. The prescribing information recommends step‐up dosing on days 1, 4, and 7 with 48–72 h of inpatient observation after each dose to monitor for CRS. This leads to a more than weeklong hospital stay, adding to the cost of therapy, resource utilization, and patient inconvenience. Here, we present a single center retrospective analysis addressing the safety and utility of a condensed step‐up dosing schedule for teclistamab. All patients who were treated with teclistamab from November 2022 to August 2023 at the Medical University of South Carolina were included in the analysis. Patients received subcutaneous (SC) teclistamab with step‐up doses (0.06 and 0.3 mg/kg) separated by either 2 or 3 (48–72 h) before the administration of the first full (1.5 mg/kg) dose (days 1, 3, and 5 ‘condensed’ schedule or days 1, 4, and 7 ‘standard’ schedule, respectively). All patients were hospitalized for the two step‐up doses and first full dose of teclistamab and received pre‐medications prior to each dose. Patients could be discharged after a minimum of 24 h following the full dose, if they did not have any CRS or ICANS. Relevant data regarding incidence, severity, and onset of CRS was collected. Statistical analysis was completed to assess the probability of fever with the first full dose of teclistamab based on incidence of fever with previous doses. A total of 25 patients were included in the analysis. Twenty‐eight percent (7/25) of patients underwent the standard step up while the remaining 72% (18/25) underwent a condensed step up of teclistamab. More than half (53%, 13/25) of the patients experienced CRS during step up dosing. Grades 1 and 2 CRS occurred in 48% (12/25) and 4% (1/25) patients, respectively. Of the 13 patients that experienced CRS, 30% (4/13) fevered with the first dose, 84% (11/13) fevered with the second dose, and one patient developed fever after the third dose. The negative predictive value of being ‘fever free’ after doses 1 and 2 and remaining ‘fever free’ throughout hospitalization was 0.92. The median length of hospital stay among the 1, 3, and 5 step up group was 6 days (6–25) and 70% (14/20) of patients were discharged from the hospital within 7 days of treatment initiation. This report demonstrates the utility of a condensed step‐up schedule for teclistamab initiation. The schedule was found to be safe and reduced hospital length of stay. These results should prompt consideration of shorter hospital stays for patients who do not experience CRS and raise the possibility of outpatient administration with close observation.