bluuebunny/crossref_metadata_2025_split huggingface dataset:
Relationship Between Perioperative Regional Anesthesia and the Risk of Missing Acute Compartment Syndrome Following Tibia Fractures
Authors: Kakalecik Jaquelyn , Satchell Christopher , Root Kevin T. , Vasilopoulos Terrie , Patrick Matthew R. , Talerico Michael T. , Krupko Thomas A. , Nin OlgaC. , Hagen Jennifer E. 
Published: June 2024

BACKGROUND:
The aim of this study was to determine the incidence of missed compartment syndrome in tibia fractures treated with and without regional anesthesia.

METHODS:
A retrospective chart review was performed of patients with operative tibial shaft or plateau fractures at a single level-one trauma hospital between January 2015 and April 2022 with a minimum of 3-month follow-up. Patients under 18 years of age, an ipsilateral knee dislocation, known neurologic injury at presentation, or prophylactic fasciotomy were excluded. We defined missed acute compartment syndrome (ACS) as a postinjury motor deficit still present at the 3-month postoperative appointment. For patients that received a peripheral nerve block, we recorded whether a continuous perineural catheter or one-time single-shot injection was performed, and the number of nerves blocked. Incidence rates for ACS were calculated with exact binomial 95% confidence intervals (CIs). Morphine milligram equivalents (MMEs) consumed 24 hours after surgery, use of nerve block, nerve block timing, and type of block were compared using Mann-Whitney and Kruskal-Wallis nonparametric tests. Statistical significance was defined as P < .05.

RESULTS:
The incidence of compartment syndrome diagnosed and treated during index hospitalization was 2.2% (17/791, 95% CI, 1.3%–3.4%). The incidence of missed ACS was 0.9% (7/791, 95% CI, 0.4%–1.8%). The incidence of missed ACS was not different between those who received nerve block 0.7% (4/610, 95% CI, 0.2%–1.7%), and those who did not (1.7% (3/176, 95% CI, 0.4%–4.8%) P = .19). Within patients receiving a nerve block, all patients with missed ACS (n = 4) received a perineural catheter. Similar missed ACS rates were observed between tibial shaft and plateau fractures. Patients receiving a nerve block had lower MME compared to those who did not receive a nerve block (P < .001).

CONCLUSIONS:
The results do not provide evidence that perioperative regional anesthesia increases the incidence of missed ACS in patients with operative tibial shaft or plateau injuries. but does decrease postoperative opioid requirements.
Novel compound heterozygous mutations in the hemojuvelin gene in a juvenile hemochromatosis patient: A case report
Authors: Xie Ling-Ding , Kong Xiao-Mu , Shen Jing-Xia , Wang Tai-Ling , Ma Jing , Zhang Yun-Fen , Chen Xiao-Ping 
Published: June 2024

BACKGROUND
Juvenile hemochromatosis (JH) is an early-onset, rare autosomal recessive disorder of iron overload observed worldwide that leads to damage in multiple organs. Pathogenic mutations in the hemojuvelin (HJV ) gene are the major cause of JH.
CASE SUMMARY
A 34-year-old male Chinese patient presented with liver fibrosis, diabetes, hypogonadotropic hypogonadism, hypophysis hypothyroidism, and skin hyperpigmentation. Biochemical test revealed a markedly elevated serum ferritin level of 4329 μg/L and a transferrin saturation rate of 95.4%. Targeted exome sequencing and Sanger sequencing revealed that the proband had a novel mutation c.863G>A (p.R288Q) in the HJV gene which was transmitted from his father, and two known mutations, c.18G>C (p.Q6H) and c.962_963delGCinsAA (p.C321*) in cis, which were inherited from his mother. The p.R288W mutation was previously reported to be pathogenic for hemochromatosis, which strongly supported the pathogenicity of p.R288Q reported for the first time in this case. After 72 wk of intensive phlebotomy therapy, the patient achieved a reduction in serum ferritin to 160.5 μg/L. The patient's clinical symptoms demonstrated a notable improvement.
CONCLUSION
This study highlights the importance of screening for hemochromatosis in patients with diabetes and hypogonadotropic hypogonadism. It also suggests that long-term active phlebotomy could efficiently improve the prognosis in severe JH.
Overall clinical course of indeterminate dendritic cell tumor patients without skin lesions: A rare case report
Authors: Liang Hao , Zhao Yun-Fei , Zhang Liu-Ping , Wu Ya-Kun 
Published: June 2024

BACKGROUND
Indeterminate dendritic cell tumor (IDCT) is a rare tumor of immune cells, and IDCT patients without skin lesions are rarely reported. Therefore, the clinical course in this type of patient is unclear, and further research on the underlying pathological mechanisms and appropriate treatments is needed.
CASE SUMMARY
This study describes a female IDCT patient with bile duct lesions. The strong mimicry of IDCT lesions confused doctors, and consequently, this patient, who had no skin lesions, was first diagnosed with cholangiocarcinoma. Then, she presented with persistent abdominal distension without jaundice. Enlarged mesenteric lymph nodes along with massive ascites were observed in the subsequent imaging examination. However, no tumor cells or pathogens were found in the three subsequent ascites analyses. It took 2 years to reach the correct diagnosis, which was eventually obtained by performing surgery for biopsy of the patient’s abdominal lymph nodes. However, by then, she was already in a cachexic state. Finally, she received a cycle of cyclophosphamide therapy and was advised to visit a hospital specializing in rare diseases.
CONCLUSION
For IDCT patients without skin lesions, early biopsy is the key to obtaining a correct diagnosis. Moreover, the collective management of IDCT patients is important. Further histological and molecular biology studies based on human specimens are critical for understanding the pathological mechanism of dendritic cell tumors in the future.
Characterization of rice varieties under salinity level and the response of defense-related genes during the germination stage
Authors: HARTATIK SRI , ROZZITA NOOR , WIBOWO SATRIYO , CHOIRUNNISA EVIYANTI , SAKANTI SAFA ADISTA SEKAR , PUSPITO AGUNG NUGROHO , UBAIDILLAH MOHAMMAD 
Published: June 2024

Abstract. Hartatik S, Rozzita N, Wibowo S, Choirunnisa E, Sakanti SAS, Puspito AN, Ubaidillah M. 2024. Characterization of rice varieties under salinity level and the response of defense-related genes during the germination stage. Biodiversitas 25: 1536-1543. Climate change causes sea level rise, leading to an increase in soil salinity. In the germination phase, rice plants are more sensitive to salinity stress. Under salinity stress, plants produce an increased content of Reactive Oxygen Species (ROS). Local rice (Oryza sativa) has complex gene properties to survive in salt-stress conditions. This research aims to study the potential of salt tolerance at the germination stage and provide a molecular analysis based on antioxidant genes in local rice. This study uses a factorial completely randomized design. The first factor is rice varieties (IR64, Silaun, Ime Buci, Me Klan, Me Likan, Me Meak, Me Taek, and Umak Klete), while the second factor is the salt treatments (0, 100, 200, 300, 400, 500, and 600 mM NaCl). The results showed that Ime Buci became the most tolerant variety to salinity stress due to its ability to survive and germinate at the highest NaCl concentration (400 mM NaCl). In addition, the H2O2 content and Malondialdehyde (MDA) values of the Ime Buci variety were lower compared to the IR64 variety. The expression of antioxidant genes (Mn-SOD, Cu/Zn SOD, Cytosolic APX, OsAPX1, CAT, OsCATA, and GPOD) was used as observational variables in this study. The results of antioxidant gene expression showed that the Ime Buci variety activated genes more than IR64 variety based on real-time PCR. However, it still needs more investigation to analyze the potential of Ime Buci in salt conditions during the vegetative and generative stages to get more information about rice's mechanism in terms of tolerating stress conditions.
Schrödinger–Hardy system without the Ambrosetti–Rabinowitz condition on Carnot groups
Authors: Chen Wenjing , Yu Fang 
Published: June 2024

In this paper, we study the following Schrödinger–Hardy system

{

−

Δ

G

u
−
μ

ψ
2

r
(
ξ

)
2

u
=

F
u

(
ξ
,
u
,
v
)

i
n

Ω
,

−

Δ

G

v
−
ν

ψ
2

r
(
ξ

)
2

v
=

F
v

(
ξ
,
u
,
v
)

i
n

Ω
,

u
=
v
=
0

o
n

∂
Ω
,

where
Ω
is a smooth bounded domain on Carnot groups

G

, whose homogeneous dimension is
Q
≥
3
,

Δ

G

denotes the sub-Laplacian operator on

G

,
μ
and
ν
are real parameters,
r
(
ξ
)
is the natural gauge associated with fundamental solution of
−

Δ

G

on

G

,
ψ
is the geometrical function defined as
ψ
=

|

∇

G

r

|

, and

∇

G

is the horizontal gradient associated with

Δ

G

. The difficulty is not only the nonlinearities

F
u

and

F
v

without Ambrosetti–Rabinowitz condition, but also the Hardy terms and the structure on Carnot groups. We obtain the existence of nonnegative solution for this system by mountain pass theorem in a new framework.
Automated handling of biological objects with a flexible gripper for biodiversity research
Authors: Wührl Lorenz , Keller Leonard , Klug Nathalie , Shirali Hossein , Meier Rudolf , Pylatiuk Christian 
Published: June 2024

Abstract
With the increasing loss of insect species, their ecosystem services such as pollination of plants and pest control are also under threat. This means that more intense monitoring is needed, but this poses many challenges: Collecting is comparatively easy and carried out at many locations worldwide using standardized methods such as Malaise traps that preserve the specimens in ethanol. However, a comprehensive, systematic evaluation of these samples at the specimen-level is not yet possible due to the large number of specimens and the lack of taxonomic experts who can identify the specimens to species level. We thus here present a new mini-gripper for the automated handling of insects preserved in ethanol. The mini-gripper automatically picks insects from bulk samples as long as they are in the 7.5 mm–15 mm size range to be transferred to the DiversityScanner, where they are classified using a trained AI model. This automated approach is currently tested in an EU project to identify new invasive pests.
RNA aptamers: promising tools in synthetic biology
Authors: Kelvin Daniel , Suess Beatrix 
Published: June 2024

Abstract
Synthetic elements made entirely of RNA are suitable as regulatory elements in genetically modified systems and as biosensors. Such RNA aptamers are highly structured nucleotide sequences capable of specifically binding a target molecule. De novo selection of aptamers against a wide variety of potential targets is possible. By integrating RNA aptamers as binding domains into natural or synthetically designed regulatory circuits in the form of so-called riboswitches, new regulatory mechanisms can be generated that do not require additional regulatory elements. In addition, these binding domains can be used in cell-free systems to perform highly specific and affine molecular detection assays. By presenting two well-established aptamer designs, we aim to demonstrate the potential of RNA aptamer-based riboswitches and biosensors in various applications.
Biocatalytic approaches for plastic recycling
Authors: Branson Yannick , Wei Ren , Bornscheuer Uwe T. 
Published: June 2024

Abstract
This article presents an overview of the evolution, impact, and challenges of plastics, focusing on the difficulties in recycling processes and introducing biocatalytic technologies as a promising solution for efficient plastic degradation. While there are many obstacles in accessability of plastics for enzymatic degradation, recent achievements in industrial application and discoveries of new enzyme classes for polymer degradation highly encourage further investment in this technology paving the way towards broad industrial application of biocatalysis in plastic recycling.
Mother tongue in Serbia: A speakers’ perspective on the meaning of the concept
Authors: Mirić Mirjana , Sokolovska Valentina , Sorescu-Marinković Annemarie 
Published: June 2024

Abstract
The present study analyzes the meanings bilingual and multilingual speakers attach to the term mother tongue, a familiar concept which is most often intuitively understood, but difficult to define. Taking as the main frame of reference the vulnerable linguistic communities of Serbia, the authors assess the answers given by the interviewees to the open question “What does the notion of mother tongue mean to you?” asked in the pilot sociolinguistic questionnaire the study is based on. The responses are classified in several categories, which are then analyzed and discussed. The findings show that the speakers give equal importance to the period of language acquisition, in early childhood, and the role of the family in language transmission for defining mother tongue. The diversity of responses obtained in the study suggests that the definitions provided by the censuses, used in the education context, human rights literature, or sociolinguistics, do not necessarily overlap with the social reality, as the actual members of the linguistic communities perceive the concept as being more heterogeneous than generally assumed and do not automatically connect it to mothers.
Utilizing ResNet for enhanced quality prediction in PET production: an AI-driven approach
Authors: Zheng Kaiwen , Shi Jiaoxue , Chen Shichang 
Published: June 2024

Abstract
To promote theoretical understanding for optimizing the entire process parameters (temperature, pressure, flow rate, etc.) and quality indicators (molar fraction, end-group concentration, and number-average molecular weight) in the industrial production of polyethylene terephthalate (PET), a dataset construction for production parameters and product quality indicators was accomplished in conjunction with industrial process simulation software. A complete deep learning workflow including data collection, dataset construction, model training, and evaluation was established. A prediction method for process-product quality of PET production based on the residual neural network (ResNet) network was proposed to reduce the complexity of quality control in polyester production. The results show that compared to traditional convolutional neural network (CNN), ResNet has higher accuracy (R
2 ≥ 0.9998) in predicting the PET production process and product quality. It can accurately establish the mapping relationship between production parameters and product quality indicators, providing theoretical guidance for intelligent production.
Lupus, der (un)bekannte Verfasser des Liber legum
Authors: Mischke Britta 
Published: June 2024

Summary
In medieval studies, the “Liber legum of Lupus of Ferrières” has long been a firmly associated pair of terms, although the identity of the author is by no means certain and has been repeatedly called into doubt. The paper reconstructs how this opinion has prevailed, and critically examines the arguments put forward in favor of it. Given the paucity of reliable evidence, adherence to the hypothesis seems to be due primarily to the appeal of combining a well-known work with a famous name. Since the sources used for the Liber legum as well as its manuscript tradition clearly point to Italy, it seems most likely that Lupus was an Italian collector of legal texts, who had a personal relationship with the patron of the work, Margrave Eberhard of Friuli.
Coding for Conditions Due to Heat Overexposure
Authors:   American Academy of Pediatrics
Published: June 2024

Physicians and other qualified health care professionals (QHPs) may see patients with varying degrees of heat-related illness during summer months. Services provided to address heat-related illness may range from an office evaluation and management (E/M) service to an emergency department (ED) visit or critical care services. This article reviews coding for some heat-related illnesses. Topics include the following:
Diagnosis codes for heat-related illnesses Example of reporting E/M of heat exhaustion Example of reporting E/M of heatstroke
Britain's Mediterranean Empire
Authors: Salmon Alice Wooledge , Dunn-Meynell Hugo 
Published: June 2024

Last autumn, the authors spent time in Gibraltar, that famous three-mile rock whose 20,000-odd inhabitants, ultra-British in allegiance, are a unique and admirable mingling of Spanish, Genoese, Maltese, Portuguese, Moorish, Irish, and English forebears, with resilient threads of Sephardic Judaism and Indian commerce among a population as complex as its tangled and tumultuous history. The streets feel Spanish, the languages switch between Spanish and English, and the Timid British Tourist - searching for sun without hazard - arrives by the thousand.
In April, Spain is due to reopen its border with 'Gib' and 'suspend' the restrictions which have isolated the country since 1969. Before the frontier shut, Gibraltar- which has virtually no local produce- bought good foodstuffs from Spain, but for the last twelve and a half years has been forced to deal for most perishables with Morocco, across the Straits, and as a captive audience, gets supplies of a take-it-or-leave-it quality. What will happen now remains to be seen, but within this temporarily artificial situation the authors found a thriving - If hidden - gastronomy, part of the Mediterranean tradition of oil, garlic, saffron, tomatoes, chick-peas, rice, marjoram, pimientos, almonds, dates, and sugar, unaffected in essence by over a decade's isolation.
Three Letters to Godard, and an Exergue
Authors: Duarte Miguel Mesquita 
Published: June 2024

What led me to write these letters to someone I never met privately, whom I never even knew, and whom I addressed after death? How audacious! Was it the desire to do justice to someone who, in my view, would have deserved a different kind of posthumous tribute, one much more honourable and distinguished? Or was it merely a means of materializing a genuinely felt emotion? Or, perhaps, an opportunity to perpetuate and keep alive a conversation that had endured for years? Isn't it true that, in a way, Godard was always dead to me, that is, inaccessible to me, and yet, or for that very reason, more open in his thought, but preserved in the silence and confidence of the unknown?
First, second and third-hand smoke exposure during pregnancy - Τhe adverse effects on the fetus: A Systematic Review
Authors: FYTROU EMMANOUELA , TASKOU CHRYSOULA , Vlachou Maria , Diamanti Athina 
Published: June 2024

IntroductionH Πρωτογενής, δευτερογενής και τριτογενής έκθεση στον καπνό του τσιγάρου αποτελεί ένα από τα πιο σοβαρά προβλήματα δημόσιας υγείας. Σύμφωνα με τον Παγκόσμιο Οργανισμό Υγείας (ΠΟΥ) το κάπνισμα είναι μια σοβαρή χρόνια ασθένεια και ο καπνιστής είναι ασθενής που χρειάζεται συχνή ιατρική παρέμβαση. Σκοπός της συγκεκριμένης συστηματικής ανασκόπησης είναι η διερεύνηση της επιρροής της πρωτογενούς, δευτερογενούς και τριτογενούς έκθεσης στον καπνό του τσιγάρου τόσο στην εγκυμοσύνη όσο και στο έμβρυο.MethodsΓια τη συστηματική ανασκόπηση, η αναζήτηση των άρθρων πραγματοποιήθηκε στην ηλεκτρονική βάση δεδομένων Medline με τη χρήση λέξεων –κλειδιών (“smoking or tobacco or first hand smoke exposure or second hand smoke exposure or third hand smoke exposure” and “pregnancy or fetus”). Τα κριτήρια ένταξης για την αναζήτηση των άρθρων ήταν οι μελέτες της ελληνικής και διεθνούς βιβλιογραφίας που αναφέρονταν στο κάπνισμα κατά τη διάρκεια της κύησης.ResultsΑπό την ανασκόπηση της βιβλιογραφίας βρέθηκαν 10.928 αποτελέσματα μελετών, επιλέχθηκαν 298 για περαιτέρω αξιολόγηση και με βάση τα κριτήρια «ένταξης-αποκλεισμού» επιλέχθηκαν να αναλυθούν 22 μελέτες. Από την ανάλυση των μελετών βρέθηκε ότι η πρωτογενής, δευτερογενής και τριτογενής έκθεση στον καπνό του τσιγάρου κατά τη διάρκεια της κύησης επιφέρει σειρά επιπλοκών τόσο στο έμβρυο όσο και στο νεογνό.ConclusionsΗ διακοπή του καπνίσματος σε οποιαδήποτε φάση της εγκυμοσύνης έχει ευεργετικά οφέλη τόσο για τη μητέρα όσο και για το έμβρυο. Επομένως η αποχή από το κάπνισμα κατά τη διάρκεια της κύησης είναι αναγκαία για την ομαλή ανάπτυξη του εμβρύου.
Los Juegos Olímpicos de 1964 y 2021: la producción del espacio para la consolidación de Tokio, Japón, como ciudad global
Authors: Montero Oropeza Jonathan , Pérez Gayosso Citlalli 
Published: June 2024

El presente texto tiene como objetivo señalar el papel de la producción del espacio en Tokio a través del equipamiento urbano que se generó para los Juegos Olímpicos de Verano de 1964 y 2021. Este escrito describe los procesos para obtener las sedes olímpicas y la reconfiguración de la capital de Japón para ambos megaeventos deportivos, lo cual permite la interpretación de ambos certámenes como piezas clave para la consolidación de Tokio como una de las ciudades más innovadoras y trascendentes a escala global.
Palabras clave: Espacio, Juegos Olímpicos, Tokio, Ciudad Global
Epistemes otras y cambio social: sentidos de lo interdisciplinario
Authors: Rueda Barrera Eduardo A. 
Published: June 2024

El trabajo aborda el papel relevante que deben jugar otras formas de conocimiento en la construcción de alternativas de superación de los problemas más importantes que enfrentan hoy las sociedades globales: la degradación ambiental local y global, la desigualdad e inequidad sociales, y la conflictividad violenta en diversas escalas. Para ello caracteriza y da razones para validar otras formas de conocimiento, particularmente aquellos saberes anclados a la experiencia social de los pueblos originarios, las mujeres y los legos, y defiende una comprensión de la interdisciplinariedad como agencia ético-política obligada a abrir, con propósitos transformadores, caminos de diálogo entre tales formas de conocimiento y las disciplinas universitarias. El sentido de dicho diálogo no es otro que el de catalizar, por efecto de tales formas de conocimiento, la producción de visiones y prácticas auténticamente innovadoras frente a los retos que hoy nos desafían.
Potensi dan Hambatan Transformasi Sistem Tempat Pengelolaan Sampah (TPS) 3R Dalam Mengembangkan Perekonomian Desa (Studi Kasus Desa Kalimojosari)
Authors: Ayu Maryani , Adinugraha Hendri Hermawan 
Published: June 2024

Penelitian ini bertujuan untuk membuktikan bahwa transformasi TPS 3R di Desa Kalimojosari efektif dalam mengembangkan perekonomian desa melalui penelitian lapangan dengan pendekatan kualitatif. TPS 3R salah satu solusi sistem pengolahan sampah yang dapat menyelesaikan permasalahan sampah. TPS berbasis 3R merupakan pola pendekatan pengelolaan persampahan pada skala komunal atau kawasan, dengan melibatkan peran aktif pemerintah dan masyarakat. TPS 3R memiliki potensi dalam kontribusinya pada proses pengembangan perekonomian desa. TPS 3R memiliki manfaat yang dapat dirasakan langsung oleh masyarakat sekitar dari berbagai sektor. Sehingga transformasi TPS 3R dapat diterapkan di berbagai wilayah terutama Desa Kalimojosari.

Kata kunci: Potensi; Transformasi Sistem; Pengelolaan Sampah; TPS 3R; Ekonomi Desa