bluuebunny/crossref_metadata_2025_split huggingface dataset:
Are charitable donations a luxury good of the rich? Evidence from a survey and actual behavior in a superdiverse metropolis
Authors: Elis Jonas , Mayer Sabrina Jasmin , Goerres Achim 
Published: July 2024

AbstractObjectivePrevious studies on charitable giving have emphasized the importance of socioeconomic status in explaining why individuals choose to donate or not to donate money. Other explanations, such as social capital or local contexts, have also been investigated, but these perspectives are rarely combined and tested against an actual behavioral outcome measure. We seek to compare the statistical importance of these explanations for individual‐level donation decisions.MethodsOur study investigates survey respondents’ choices to repeatedly donate their earned incentive after a completed interview in the three waves of the Immigrant German Election Study II from 2021. In each wave, respondents were offered an incentive worth 10 euros, which they could either keep as a gift card or donate to the local food bank. This decision is a measurement of real rather than self‐reported donation behavior. We combine individual‐level variables and neighborhood‐level variables that capture the heterogeneity of our sample to systematically compare explanations for this donation decision.ResultsWe find that the respondents’ self‐assessed economic situation and sociopolitical preferences in favor of more social spending by the state, rather than the respondents’ objective socioeconomic status, have strong positive effects on the total amount donated throughout the survey.ConclusionNot the rich per se, but those who think they are doing well economically, and who are on the redistributive left, give more to others. These findings remain robust after controlling for the strong heterogeneity of our sample.
Statistical Analysis of Flux Enhancements of Energetic Electrons in the Low-Latitudinal Ionosphere According to the Data from the NOAA/POES and MetOp Satellites from 1998 to 2022
Authors: Golubkov M. G. , Suvorova A. V. , Dmitriev A. V. , Golubkov G. V. 
Published: July 2024

Abstract
The intense precipitation of energetic electrons from the Earth’s radiation belt (ERB) is one of the most important sources of ionization in the ionosphere and atmosphere. A large-scale statistical analysis is carried out of the data from continuous low-orbit satellite observations of solar-cycle variations in the flux enhancements of the ERB electrons with energy >30 keV at an altitude of 850 km, acquired from the NOAA/POES and MetOp satellites in the interval from 1998 to 2022. The basic features of artificial failures in the satellite database with high-time resolution measurements in the interval from 2014 to 2022 are found and described. Appropriate data correction is carried out. It is shown that the average annual number of days with electron flux enhancements increases rapidly within three years after the solar-cycle maximum and reaches its greatest value near the middle of the declining phase of solar activity. Then the frequency of event occurrence begins to decrease noticeably within an 8-year interval, including the minimum, rising, and maximum phases of the solar cycle. The minimum level is achieved at the maximum solar activity.
Proteomic and phenotypic characteristics of memory-like natural killer cells for cancer immunotherapy
Authors: Arellano-Ballestero Helena , Zubiak Agnieszka , Dally Chris , Orchard Kim , Alrubayyi Aljawharah , Charalambous Xenia , Michael Melina , Torrance Robert , Eales Trinity , Das Kushal , Tran Maxine G. B. , Sabry May , Peppa Dimitra , Lowdell Mark W. 
Published: July 2024

BackgroundHuman and mouse natural killer (NK) cells have been shown to develop memory-like function after short-term exposure to the cocktail of IL-12/15/18 or to overnight co-culture with some tumor cell lines. The resulting cells retain enhanced lytic ability for up to 7 days as well as after cryopreservation, and memory-like NK cells (mlNK) have been shown to induce complete remissions in patients with hematological malignancies. No single phenotype has been described for mlNK and the physiological changes induced by the short-term cytokine or tumor-priming which are responsible for these enhanced functions have not been fully characterized. Here, we have generated mlNK by cytokine and tumor-priming to find commonalities to better define the nature of NK cell “memory” in vitro and, for the first time, in vivo.MethodsWe initiated mlNK in vitro from healthy donors with cytokines (initiated cytokine-induced memory-like (iCIML)-NK) and by tumor priming (TpNK) overnight and compared them by high-dimensional flow cytometry, proteomic and metabolomic profiling. As a potential mechanism of enhanced cytolytic function, we analyzed the avidity of binding of the mlNK to NK-resistant tumors (z-Movi). We generated TpNK from healthy donors and from cancer patients to determine whether mlNK generated by interaction with a single tumor type could enhance lytic activity. Finally, we used a replication-incompetent tumor cell line (INKmune) to treat patients with myeloid leukaemias to potentiate NK cell function in vivo.ResultsTumor-primed mlNK from healthy donors and patients with cancer showed increased cytotoxicity against multiple tumor cell lines in vitro, analogous to iCIML-NK cells. Multidimensional cytometry identified distinct memory-like profiles of subsets of cells with memory-like characteristics; upregulation of CD57, CD69, CD25 and ICAM1. Proteomic profiling identified 41 proteins restricted to mlNK cells and we identified candidate molecules for the basis of NK memory which can explain how mlNK overcome inhibition by resistant tumors. Finally, of five patients with myelodysplastic syndrome or refractory acute myeloid leukemia treated with INKmune, three responded to treatment with measurable increases in NK lytic function and systemic cytokines.ConclusionsNK cell “memory” is a physiological state associated with resistance to MHC-mediated inhibition, increased metabolic function, mitochondrial fitness and avidity to NK-resistant target cells.
Open-capsule budesonide for the treatment of immune-related enteritis from checkpoint inhibitors
Authors: Magahis Patrick Tiongco , Corso Tara , Livingstone Pamela , Tom Erika , Srivastava Amitabh , Postow Michael , Faleck David 
Published: July 2024

BackgroundLimited data exist for management strategies targeting immunotherapy-related enteritis (irEnteritis). Systemic corticosteroids are commonly used but often are limited by adverse events. Enteric corticosteroids such as budesonide offer an attractive alternative; however, the ileocolonic release of enteric-coated budesonide has limited utility for diffuse enteritis. Open-capsule budesonide (OCB) is a novel therapeutic approach that offers drug delivery throughout the small bowel. We report outcomes in patients treated with OCB for confirmed or suspected irEnteritis.MethodsThis retrospective cohort included all individuals treated with OCB for irEnteritis at Memorial Sloan Kettering from July 2018 to August 2023. Primary outcomes included clinical response, clinical remission, and corticosteroid-free remission following OCB. Secondary outcomes were OCB-related adverse events and efficacy by gastrointestinal toxicity location.Results19 patients (53% female) with irEnteritis were treated with OCB. All patients presented with diarrhea; 15 (79%) reported anorexia with median 6 kg weight loss. 17 patients (89%) underwent esophagogastroduodenoscopy with biopsies revealing enteritis in all; 8 (42%) had concomitant colitis. 15 (79%) patients were treated previously with systemic corticosteroids: 8 (53%) were corticosteroid-dependent while 7 (47%) demonstrated non-response. 18 patients (95%) achieved clinical response, 15 (79%) attained clinical remission, and 11 (58%) had corticosteroid-free remission. Response to OCB was rapid with improvement noted after a median 4 days. 14 (74%) patients restored their pre-irEnteritis weight by OCB cessation. One mild, self-resolving adverse event was reported.ConclusionsOCB is a safe and effective therapy for irEnteritis. OCB avoids systemic immunosuppression and successfully achieves clinical response and remission even in patients previously nonresponsive to systemic corticosteroids. Future studies are needed to optimize indications and duration.
Computational analysis of carboxymethyl cellulose water-based Casson hybrid nanofluid (Al2O3-CuO) flow past a wedge, cone and plate
Authors: Karthikeyan S. , Ali Farhan , Thamaraikannan N. , Loganathan K. 
Published: July 2024

The swift advancement of heat transfer technologies can be attributed to the growing need for effective heating and cooling systems in various sectors, including the automotive, chemical, and aerospace industries. This work aims to examine the impact of radiation on the behavior of Casson hybrid nanoparticles (Al2O3-CuO) mixed convective flow in three distinct scenarios. The physical properties of copper oxide (CuO) and aluminum oxide (Al2O3) nanoparticles are utilized when mixed with CMC-water as the solvent. This paper aims to analyze the influence of mixed convective flow on the thermal integrity of hybrid nanoparticles when subjected to a wedge, cone, and plate. The analysis of chemical reactions and the existence of a permeable substance is also incorporated. The partial differential systems are appropriately transformed into a system of ordinary differential equations (ODEs). In addition, the calculation of this system of ODEs is carried out using the analytical technique known as the homotopy analysis approach (HAM). The study examines potential resolutions for flow issues in three distinct configurations: wedge, cone, and plate. A comprehensive examination and record of the impacts of various physical characteristics is carried out. The concepts of wall friction, Nusselt number, and Sherwood number, among others, are explained through the utilization of graphical representations. The porosity and Casson fluid characteristics cause a decrease in the performance of the velocity profile. Hybrid nanofluids have superior heat transfer efficiency compared to conventional nanofluids.
Vibration control and transmission mechanism of super high-rise building located on subway based on spring vibration isolation system
Authors: Mei Can , Wang Dayang , Zhang Yongshan 
Published: July 2024

This study focuses on the vibration control effect of the spring vibration isolation system (SVIS) on a super high-rise building located on the subway (BLS) and the transmission mechanism of vibration in super high-rise BLS. Firstly, the 1:35 scale shaking table test model of super high-rise BLS is designed, the rationality of the shaking table test model is verified, and the shaking table test is implemented. Secondly, the finite element model (FEM) is established and verified based on the results of the shaking table test. Finally, based on verified FEM, the vibration control effect of SVIS on super high-rise BLS and the vibration transmission mechanism of super high-rise BLS is analyzed. The results show that the vibration response of the BLS show amplification trend along the height direction. The amplification of vibration response of BLS is effectively controlled by SVIS. The higher the floor, the greater the reduction coefficient, and the better the control effect. The reduction coefficient above 10F is mainly distributed above 0.80 due to the SVIS. The BLS equipped with the SVIS maintains the degree of Z-direction vibration and 1/3 octave vibration acceleration level that is within the limits stipulated by the specifications. The first-order vertical frequency of BLS equipped with the SVIS is adjusted from 65 Hz to 8 Hz, far from the favorable frequency range of the subway wave.
Protocolized Foot Exercises Help in Improvement of Diabetic Foot Ulcers and Quality of Life When Added to Standard Therapy–A Randomized Clinical Trial
Authors: Nayak Deepak , Ray Rubik , Anand Chetan , Baruah Tridip Dutta , Goyal Ashok 
Published: July 2024

Context Diabetic foot disease is the major cause of nontraumatic limb amputations worldwide causing a high socioeconomic and psychological toll and a huge burden to the healthcare system. Currently, standard treatment of diabetic foot ulcer is through multidisciplinary therapy. Foot exercises have been shown to improve healing in diabetic ulcers although evidence is limited and applicability is non-uniform. Our study aimed to generate more evidence regarding the benefit of addition of protocolized foot exercises so that it can be instituted as a standard of care. Methods and Material It was an open label Randomized controlled trial with seventy-two patients and study duration of one and half years Patients with diabetic foot ulcers were randomized into two groups. Both groups received standard therapy for diabetic foot ulcer. The intervention group in addition received three months of protocolized foot exercises. At the end of three months ulcer healing and quality of life were m compared among both the groups. Results Regular exercises for three months caused significant reduction in ulcer area compared to the non-intervention group [100% versus 45.22%, 95% CI =36.30(16.04—56.56), P-value = 0.001]. Quality of life analyzed by SF-36 score showed significant improvement in components like physical function [69.4 ± 8.9 versus 63.7 ± 11.0, 95% CI = 5.73 (0.97-10.48), P-value = 0.01], emotional well-being [65.2 ± 7.6 versus 60.8 ± 7.9, 95% CI = 4.44 (0.79-8.10), P-value = 0.01], and pain components [55.4 ± 18.5 versus 47.5 ± 14.5, 95% CI = 7.99 (0.16-15.81), P-value = 0.04) at 3 months although change in social functioning, physical health limitation, health change, energy and general health improvement were not significant. Conclusions Addition of protocolized foot exercises are beneficial for patients of diabetic foot ulcers in terms of ulcer healing as well as improvement of quality of life provided compliance to exercises can be ensured.
Reliability assessment of distal occlusion eTICI scoring
Authors: Dolia Jaydevsinh N , Grossberg Jonathan A , Martins Pedro N , Tarek Mohamed A , Pabaney Aqueel , Al-Bayati Alhamza R , Nogueira Raul G , Haussen Diogo C 
Published: July 2024

Background The eThrombolysis in Cerebral Infarction (eTICI) score has been validated in proximal large artery occlusion (pLAOs). Despite the growing number of distal medium vessel occlusions (DMVOs) mechanical thrombectomies (MT) and the widespread utilization of the eTICI scoring system, its reliability and standardization for more distal occlusions have not been validated. We aim to evaluate the interrater reliability of eTICI scores in primary DMVOs. Methods This was a retrospective analysis of a prospectively maintained database for consecutive patients with pLAO and DMVO MT at a single comprehensive stroke center from 2015 to 2022. Two fellowship-trained neurointerventionalists blindly/independently assessed digital subtraction angiograms for final eTICI, followed by consensus reads for discrepancies. Results 59 DMVO of 2248 thrombectomies [M3:29(50%)/M4:1(2%)/A1:3(5%)/A2:12(22%)/A3: 5(9%)/P1:7(12%)/P2:1(2%)] and 124 pLAOs of 308 thrombectomies [i-ICA:13(11%)/MCA-M1: 111(90%)] were included. The distribution of final eTICI scores was comparable between pLAO vs DMVOs (p = 0.82). The pLAO final eTICI score assessment between two readers demonstrated moderate reliability with a kappa0.77 (95%CI: 0.67–0.88), while the DMVO eTICI score assessment exhibited almost-perfect agreement with kappa 0.94 (95%CI: 0.90–0.99). The agreement between the consensus read and the original report in DMVOs was 0.86 (95% CI: 0.71–1.00) while for pLAO it was 0.83(95% CI: 0.76–0.90). The performance of eTICI was comparable amongst different DMVO territories as well as for distal vs. very distal occlusions. Conclusion eTICI score exhibited comparable performance for DMVO as compared to pLAO strokes. Further studies investigating DMVO eTICI grading and clinical outcomes are warranted.
Rescue extracranial vertebral stenting in tandem occlusions: A preliminary Vietnamese study
Authors: Minh Thang Le , Chi Cuong Tran , Hoai Nam Nguyen , Hoang Dinh Nguyen , Luu Giang Nguyen , Nhat Huy Nguyen Dao , Hoang Linh Duong , Tran Tran Nguyen , Bao Luan Tran Minh 
Published: July 2024

Background and Purpose The acute vertebrobasilar occlusion associated with the poor prognosis, particularly tandem occlusion. However, few data on the efficacy of the endovascular therapy was indicated in this occlusion. We investigated whether the additional rescue extracranial vertebral stenting improved clinical outcome by modified Rankin scale (mRS) score within 3 months after the procedure. Methods This was a retrospective analysis of patients with acute posterior tandem occlusion who were treated with rescue extracranial vertebral stenting between December 2020 and January 2024 at our hospital. Clinical, neuroimaging, procedural, and complication data were collected. Primary outcomes included the rate of good outcomes (mRS ≤ 2) at 3-month follow-up. Results Nine patients who underwent rescue extracranial vertebral stenting in posterior circulation tandem occlusions were enrolled in the study. All patients were achieved the successful recanalization (mTICI ≥ 2b). Of Dotter technique in the “distal-to-proximal” approach, Diagnostic-Dotter made up 66.7%. Five patients (55.6%) with good outcome (mRS ≤ 2) at 3 months, and 1 patient (11.1%) underwent suboccipital decompressive craniectomy due to the malignant cerebellar infarction. Conclusion Our study suggests that despite the small series with posterior tandem occlusions, the rescue extracranial vertebral stenting could be an important alternative treatment followed by mechanical thrombectomy.
Engaging with the public on their views on the collection, use and sharing of personal health information: Development of a scenario-based survey instrument
Authors: Tuohy Ella , Murphy-Dooley Alana , Flaherty Sarah Jane , Duggan Catherine , Foley Barbara , Flynn Rachel 
Published: July 2024

Background Members of the public differ regarding their views on the use and sharing of personal health information. Objective This paper describes the methodology employed to develop a telephone-based survey tool to capture views of the public on the collection, use and sharing of personal health information. Method A rigorous methodology comprising multiple stages was undertaken to develop a vignette/scenario-based survey instrument. These steps included a review of instruments used in other jurisdictions, focus groups, engagement meetings with healthcare professionals, cognitive testing and piloting the final instrument. Informed by the findings of each survey development phase, draft scenarios and accompanying questions were developed. Results The following scenarios were developed: ‘Circle of care,’ ‘Use of information beyond your direct care’ and ‘Digital records.’ Conclusion The findings from this survey will inform national policy in relation to health information and will inform the development and implementation of eHealth initiatives. In turn, this should support the delivery of high-quality, effective health and social care. The learnings from the development of this survey will contribute to future health information policy and governance in countries or jurisdictions considering the development of a national electronic health record system. Moreover, this research will support public and population health management by encouraging public engagement to support successful implementation of new health information systems.
Morpho-anatomical studies of family lamiaceae species of district Lahore, Punjab: a revision to flora of Pakistan
Authors: Majeed Javaria , Shaheen Shabnum , Waheed Muhammad , Abbas Moneeza , Ghani Nadia , Ashfaq Muhammad , Hashem Abeer , Kumar Ajay , Abd-Allah Elsayed Fathi 
Published: July 2024

Abstract
Background
This study was aimed to determine the taxonomic position and delimitation of fifteen Lamiaceae taxa using leaf epidermal morpho-anatomical features in Lahore. A main objective of the study was also the revision and upgradation of Lamiaceae taxa in the flora of Pakistan, as no details of studied species are found in the flora of Pakistan.

Methods
The examination of significant anatomical parameters, such as epidermal cell shape and size, stomatal types, guard and subsidiary cells shape and size, stomatal cavity size, trichome size and shape, oil droplets, crystals, and secretory cavity characteristics were studied using light microscopic (LM) and scanning electron microscopic (SEM) techniques. Among all the studied Lamiaceae species, these anatomical features varied significantly. Principal component analysis and correlation were done to distinguish the species’ similarities.

Results
Most species had pentagonal and hexagonal epidermal cells with straight anticlinal wall thickness. On the adaxial surface, paracytic stomata were found in Ocimum basilicum L. and Rosmarinus officinalis L. Diacytic stomata was observed in Ajuga reptans L. and anisocytic stomata in Galeopsis tetrahit L. In the abaxial surface, trichomes were present in five species, i.e., Mentha suaveolens Ehrh. A. reptans, Thymus vulgaris L., M. haplocalyx, and Salvia splendens Ewat. In S. splendens, peltate and glandular trichomes were seen whereas, in other species, trichomes were long, unbranched glandular and had tapering ends. In adaxial side trichomes were present only in M. suaveolens, A. reptans, S. bazyntina, O. basciculum, S. splendens, S. officinalis, S. rosemarinus. In other species, trichomes were absent on the adaxial surface. In abaxial view, M. suaveolens had the largest length of trichomes, and O. basciculum had the smallest. S. splendens L. had the largest trichome width, while T. vulgaris had the smallest.

Conclusion
Hence, according to these findings, morpho-anatomical traits are useful for identifying Lamiaceae taxa. Also, there is a need of upgradation and addition of studied taxa in flora of Pakistan comprehensively.
Genetic characteristic of mumps virus from 2012 to 2016 and its serum antibody level among general healthy population during 2018–2020 in Jiangsu Province, China
Authors: Deng Xiuying , Hu Ying , Lu Peishan , Wang Zhiguo , Guo Hongxiong 
Published: July 2024

AbstractMumps is a vaccine-preventable disease with high contagious capability. Its incidence declined rapidly since one dose of mumps vaccine was introduced into Expanded Program of Immunization (EPI) in 2008 in China. Nonetheless, the outbreaks of mumps remain frequent in China. Here we aim to assess herd immunity level followed by one-dose mumps ingredient vaccine and to elucidate the genetic characteristics of mumps viruses circulating in the post vaccine era in Jiangsu province of China. The complete sequences of mumps virus small hydrophobic(SH) gene were amplified and sequenced; coalescent-based Bayesian method was used to perform phylogenetic analysis with BEAST 1.84 software. Commercially available indirect enzyme-linked immune-sorbent IgG assay was used for the quantitative detection of IgG antibody against mumps virus. Our results show that genotype F was the predominant mumps viruses and belonged to indigenous spread, and most of Jiangsu sequences clustered together and formed a monophyly. The prevalence of mumps reached a peak in 2012 and subsequently declined, which presented an obvious different trajectory with virus circulating in other regions of China. The gene diversity of viruses circulating in Jiangsu province was far less than those in China. The antibody prevalence reached 70.42% in the general population during 2018 to 2020. The rising trend of antibody level was also observed. Although mumps antibody prevalence does not reach expected level, mumps virus faces higher pressure in Jiangsu province than the whole of China. To reduce further the prevalence of mumps viruses, two doses of mumps vaccine should be involved into EPI.