bluuebunny/crossref_metadata_2025_split huggingface dataset:
George Fu Gao: the past and future of Ebola
Authors: Poo Mu-ming , Wang Ling 
Published: February 2015

Abstract
Newly returned from the frontline of the battle against Ebola in West Africa, Dr George Fu Gao talked to NSR on this largest Ebola epidemic in history. As Deputy Director-General of the Chinese Center for Disease Control and Prevention (China CDC), an Academician of the Chinese Academy of Sciences and a fellow of the Third World Academy of Sciences (TWAS), Dr Gao has been personally involved in the fight against acute infectious diseases both on the laboratory bench and in the field for many years. Recalling the sight of an Ebola-infected young man stumbling to his death on the street and observing the continuing climb of patient statistics, he anxiously calls for larger global help to affected countries. The help provided by the world community to West Africa was ‘too late and insufficient’, and in this age of globalization ‘no country can care only for herself alone’. In this interview, Dr Gao also reviews the history, progression, and prognosis of the Ebola epidemic, the cause of failure in the early prevention and containment of the disease, the role of government policies and public health systems, and global prospects and strategies for similar acute infectious diseases in the future.
High dispersion spectroscopy of solar-type superflare stars. I. Temperature, surface gravity, metallicity, and vsin i
Authors: Notsu Yuta , Honda Satoshi , Maehara Hiroyuki , Notsu Shota , Shibayama Takuya , Nogami Daisaku , Shibata Kazunari 
Published: February 2015

Abstract
We conducted high-dispersion spectroscopic observations of 50 superflare stars with Subaru High Dispersion Spectrograph (HDS), and measured the stellar parameters of them. These 50 targets were selected from the solar-type (G-type main sequence) superflare stars that we had discovered from the Kepler photometric data. As a result of these spectroscopic observations, we found that more than half (34) of our 50 targets have no evidence of binary systems. We then estimated the effective temperature (Teff), surface gravity (log g), metallicity ([Fe/H]), and projected rotational velocity (vsin i) of these 34 superflare stars on the basis of our spectroscopic data. The accuracy of our estimations is higher than that of the Kepler Input Catalog (KIC) values, and the differences between our values and KIC values [(ΔTeff)rms ∼ 219 K, (Δlog g)rms ∼ 0.37 dex, and (Δ[Fe/H])rms ∼ 0.46 dex] are comparable to the large uncertainties and systematic differences of KIC values reported by the previous researchers. We confirmed that the estimated Teff and log g values of the 34 superflare stars are roughly in the range of solar-type stars. In particular, these parameters and the brightness variation period (P0) of nine of the stars are in the range of “Sun-like” stars (5600 ≤ Teff ≤ 6000 K, log g ≥ 4.0, and P0 &gt; 10 d). Five of the 34 target stars are fast rotators (vsin i ≥ 10 km s−1), while 22 stars have relatively low vsin i values (vsin i &lt; 5 km s−1). These results suggest that stars that have spectroscopic properties similar to the Sun can have superflares, and this supports the hypothesis that the Sun might cause a superflare.
A new enigmatic Late Miocene mylodontoid sloth from northern South America
Authors: Rincón Ascanio D. , McDonald H. Gregory , Solórzano Andrés , Flores Mónica Núñez , Ruiz-Ramoni Damián 
Published: February 2015

A new genus and species of sloth (Eionaletherium tanycnemiusgen. et sp. nov.) recently collected from the Late Miocene Urumaco Formation, Venezuela (northern South America) is herein described based on a partial skeleton including associated femora and tibiae. In order to make a preliminary analysis of the phylogenetic affinities of this new sloth we performed a discriminate analysis based on several characters of the femur and tibia of selected Mylodontoidea and Megatherioidea sloths. The consensus tree produced indicates that the new sloth,E. tanycnemius, is a member of the Mylodontoidea. Surprisingly, the new taxon shows some enigmatic features among Neogene mylodontoid sloths, e.g. femur with a robust lesser trochanter that projects medially and the straight distinctly elongated tibia. The discovery ofE. tanycnemiusincreases the diversity of sloths present in the Urumaco sequence to ten taxa. This taxon supports previous studies of the sloth assemblage from the Urumaco sequence as it further indicates that there are several sloth lineages present that are unknown from the better sampled areas of southern South America.
Phen-Gen: Combining Phenotype and Genotype to Analyze Rare Disorders
Authors: Javed Asif , Agrawal Saloni , Ng Pauline C. 
Published: February 2015

AbstractWe introduce Phen-Gen, a method which combines patient’s disease symptoms and sequencing data with prior domain knowledge to identify the causative gene(s) for rare disorders. Simulations reveal that the causal variant is ranked first in 88% cases when it is coding; which is 52% advantage over a genotype-only approach and outperforms existing methods by 13-58%. If disease etiology is unknown, the causal variant is assigned top-rank in 71% of simulations.
The Cyst Nematode Effector Protein 10A07 Targets and Recruits Host Posttranslational Machinery to Mediate Its Nuclear Trafficking and to Promote Parasitism in Arabidopsis
Authors: Hewezi Tarek , Juvale Parijat S. , Piya Sarbottam , Maier Tom R. , Rambani Aditi , Rice J. Hollis , Mitchum Melissa G. , Davis Eric L. , Hussey Richard S. , Baum Thomas J. 
Published: February 2015

Abstract
Plant-parasitic cyst nematodes synthesize and secrete effector proteins that are essential for parasitism. One such protein is the 10A07 effector from the sugar beet cyst nematode, Heterodera schachtii, which is exclusively expressed in the nematode dorsal gland cell during all nematode parasitic stages. Overexpression of H. schachtii 10A07 in Arabidopsis thaliana produced a hypersusceptible phenotype in response to H. schachtii infection along with developmental changes reminiscent of auxin effects. The 10A07 protein physically associates with a plant kinase and the IAA16 transcription factor in the cytoplasm and nucleus, respectively. The interacting plant kinase (IPK) phosphorylates 10A07 at Ser-144 and Ser-231 and mediates its trafficking from the cytoplasm to the nucleus. Translocation to the nucleus is phosphorylation dependent since substitution of Ser-144 and Ser-231 by alanine resulted in exclusive cytoplasmic accumulation of 10A07. IPK and IAA16 are highly upregulated in the nematode-induced syncytium (feeding cells), and deliberate manipulations of their expression significantly alter plant susceptibility to H. schachtii in an additive fashion. An inactive variant of IPK functioned antagonistically to the wild-type IPK and caused a dominant-negative phenotype of reduced plant susceptibility. Thus, exploitation of host processes to the advantage of the parasites is one mechanism by which cyst nematodes promote parasitism of host plants.
Preliminary evaluation of a forensic dual diagnosis intervention
Authors: Tibber Marc Samuel , Piek Nicola , Boulter Sara 
Published: February 2015

Purpose– This study is apost hocservice level investigation into the efficacy of a forensic dual diagnosis intervention. The treatment programme incorporated the principles of cognitive behavioural therapy and Motivational Interviewing, and was comprised of three stages: psycho-education into the links between mental/physical health, substance use and offending, the cultivation of coping strategies and relapse prevention planning. The paper aims to discuss these issues.Design/methodology/approach– Treatment outcome was tracked using pre- and post- stage 1 and 2 measures, and included self-report questionnaires that probed service users’ readiness for change, motivations for treatment and perceived effectiveness of coping strategies (n=80 and 37 patients for stages 1 and 2, respectively). In addition, service users undertook a knowledge “quiz”, which probed information retention.Findings– The results show that whilst psycho-education (stage 1) increased service users’ knowledge of key issues, this had no parallel effects on other measures. In contrast, completion of stage 2 led to an increase in external motivation for treatment, although this did not translate into a shift in service users’ readiness for change.Research limitations/implications– These findings are consistent with the Motivational Interviewing literature and highlight the need for a shift in internalised motivation for treatment if change is to be elicited. Further, they point towards the viability of using self-report measures to monitor treatment outcome in a secure forensic setting.Originality/value– These findings have a number of implications for the design and on-going evaluation of forensic dual diagnosis services, an area of research that is currently under-represented in the literature.
Dual diagnosis among veterans in the United States
Authors: Crane Cory A. , Schlauch Robert C. , Easton Caroline J. 
Published: February 2015

Purpose
– Over the course of their service, veterans are exposed to elevated levels of chronic stress that contribute to a greater prevalence of mental illness than observed in the general population. When mental illness is present, comorbidity is normative. Convergent evidence suggests that co-occurring substance use and mental illness is among the most prevalent forms of comorbidity within veteran samples. The purpose of this paper is to explore issues associated with dual diagnoses among veterans in the USA.

Design/methodology/approach
– Research on dual diagnoses among veterans was reviewed and consolidated for presentation into three substantive content areas consisting of prevalence, associated conditions, and treatment of dual diagnoses.

Findings
– Dually diagnosed veterans represent a group at particularly high risk for myriad adverse biopsychosocial and treatment outcomes, including poor health, suicidality, violence or aggressive behavior, arrest, homelessness, and unemployment. A comprehensive strategy has been implemented within the Veterans Health Administration to address dual diagnosis and related problems. Additional research is required to more readily identify co-occurring substance use and mental illness and to refine integrated intervention approaches to minimize burden while improving treatment outcomes for veterans and their families.

Originality/value
– The current review includes a wide range of research spanning more than two decades and describing dual diagnosis among combat veterans of all modern eras. Areas in need of further research (e.g. dual diagnosis among female veterans; early detection of psychopathology and fully integrated care among returning veterans) are identified and discussed.
Factors associated with smoking and smoking cessation among primary care patients with depression: a naturalistic cohort study
Authors: Gilchrist Gail , Davidson Sandra , Middleton Aves , Herrman Helen , Hegarty Kelsey , Gunn Jane 
Published: February 2015

Purpose
– People with a history of depression are more likely to smoke and less likely to achieve abstinence from smoking long term. The purpose of this paper is to understand the factors associated with smoking and smoking cessation among patients with depression.

Design/methodology/approach
– This paper reports on smoking prevalence and cessation in a cohort of 789 primary care attendees with depressive symptoms (Centre for Epidemiologic Studies Depression Scale score of=16) recruited from 30 randomly selected Primary Care Practices in Victoria, Australia in 2005.

Findings
– At baseline, 32 per cent of participants smoked. Smokers were more likely to be male, unmarried, receive government benefits, have difficulty managing on available income, have emphysema, a chronic illness, poor self-rated health, to have more severe depressive and anxiety symptoms, to be taking anti-depressants, to be hazardous drinkers, to report suicidal ideation and to have experienced childhood physical or sexual abuse. At 12 months, 20 participants reported quitting. Females and people with good or better self-rated health were significantly more likely to have quit, while people with a chronic illness or suicidal ideation were less likely to quit. Smoking cessation was not associated with increases in depression or anxiety symptoms. Only six participants remained quit over four years.

Practical implications
– Rates of smoking were high, and long-term cessation was low among primary care patients with depressive symptoms. Primary care physicians should provide additional monitoring and support to assist smokers with depression quit and remain quit.

Originality/value
– This is the first naturalistic study of smoking patterns among primary care attendees with depressive symptoms.
Clinician experiences of administering the Essen Climate Evaluation Schema (EssenCES) in a forensic intellectual disability service
Authors: Chester Verity , McCathie Julia , Quinn Marian , Ryan Lucy , Popple Jason , Loveridge Camilla , Spall Jamie 
Published: February 2015

Purpose
– Social climate (ward atmosphere) affects numerous treatment outcomes. The most commonly used measure is the Essen Climate Evaluation Schema (EssenCES) (Schalast et al., 2008). Though studies have investigated the psychometric properties of EssenCES in intellectual disability populations, few have focused on the clinical utility, or accessibility of the measure. The purpose of this paper is to examine clinician's experiences of using this measure with this population.

Design/methodology/approach
– Clinicians experienced in administering EssenCES with forensic intellectual disability patients completed an open-ended questionnaire, which sought qualitative data on their experiences of using EssenCES with this population. Data were analysed using thematic analysis.

Findings
– A number of issues were raised regarding use of EssenCES with patients with intellectual disability. Four overarching themes arose: Understanding of Language, Commenting on Others, Understanding of Likert Scale, and Scale Positives and Adaptation. Clinicians felt certain items were not uniformly understood by all patients, particularly those that incorporated abstract concepts, double negatives, or complex language.

Originality/value
– Results suggest forensic intellectual disability patients vary in their ability to understand EssenCES items. This resulted in significant further explanation by the administering clinician, a practice which raised concern regarding reliability. Results provide preliminary evidence to indicate EssenCES use requires further consideration in intellectual disability services, or adaptation for this client group.
An examination of factors that influence the number of information security policy violations in Qatari organizations
Authors: Al-Mukahal Hasan M. , Alshare Khaled 
Published: February 2015

Purpose
– This paper aims to investigate factors that impact the number of information security policy violations in Qatari organizations and to examine the moderating effect of Hofstede’s cultural dimensions on the relationships between the independent factors and the number of information security policy violations.

Design/methodology/approach
– Grounded in related theories from the fields of criminology, behavioral psychology and theory of planned behavior, two components that affect the number of information security policy violations were identified. A quantitative approach was used by developing a questionnaire survey to collect the data. The research model was tested using 234 employees from different Qatari organizations.

Findings
– The results of the study indicate that trust, the impact of implementing information security policy on work environment and the clarity of the scope of the information security policy were significant factors in predicting the number of information security policy violations. The findings also reveal that cultural dimensions such as uncertainty avoidance and collectivism moderate the relationships between trust, clarity of policy scope and impact of information security policy on work environment and the number information security policy violations.

Research limitations/implications
– The generalizability of the results is limited because the sample of the study was drawn from only one developing country. Therefore, a plausible future research could be testing the proposed model in many developing and developed countries.

Practical implications
– The paper includes practical implications for developing and implementing security measures and policies in diversified work environments.

Originality/value
– This study fulfils a gap in investigating the factors that influence the number of information security policy violations and the moderating effect of cultural dimensions in developing countries such as Qatar.
A new hierarchical intrusion detection system based on a binary tree of classifiers
Authors: Ahmim Ahmed , Ghoualmi Zine Nacira 
Published: February 2015

Purpose– The purpose of this paper is to build a new hierarchical intrusion detection system (IDS) based on a binary tree of different types of classifiers. The proposed IDS model must possess the following characteristics: combine a high detection rate and a low false alarm rate, and classify any connection in a specific category of network connection.Design/methodology/approach– To build the binary tree, the authors cluster the different categories of network connections hierarchically based on the proportion of false-positives and false-negatives generated between each of the two categories. The built model is a binary tree with multi-levels. At first, the authors use the best classifier in the classification of the network connections in category A and category G2 that clusters the rest of the categories. Then, in the second level, they use the best classifier in the classification of G2 network connections in category B and category G3 that represents the different categories clustered in G2 without category B. This process is repeated until the last two categories of network connections. Note that one of these categories represents the normal connection, and the rest represent the different types of abnormal connections.Findings– The experimentation on the labeled data set for flow-based intrusion detection, NSL-KDD and KDD’99 shows the high performance of the authors' model compared to the results obtained by some well-known classifiers and recent IDS models. The experiments’ results show that the authors' model gives a low false alarm rate and the highest detection rate. Moreover, the model is more accurate than some well-known classifiers like SVM, C4.5 decision tree, MLP neural network and naïve Bayes with accuracy equal to 83.26 per cent on NSL-KDD and equal to 99.92 per cent on the labeled data set for flow-based intrusion detection. As well, it is more accurate than the best of related works and recent IDS models with accuracy equal to 95.72 per cent on KDD’99.Originality/value– This paper proposes a novel hierarchical IDS based on a binary tree of classifiers, where different types of classifiers are used to create a high-performance model. Therefore, it confirms the capacity of the hierarchical model to combine a high detection rate and a low false alarm rate.
Influential factors of online fraud occurrence in retailing banking sectors from a global prospective
Authors: Sun Yan , Davidson Ian 
Published: February 2015

Purpose
– This paper aims to focus on online fraud occurrence in retailing banking sectors both in the UK and China. Online financial transactions bring convenience to individuals dramatically and improve banking service quality efficiently. However, the latest service channel, Internet, has been exploited by fraudsters excessively, standing at a huge monetary loss worldwide.

Design/methodology/approach
– In aspects of demographic factors, financial activities and IT usage, results would benefit financial organisations and local authorities in strengthening customers’ education and improving policymaking. The fraud occurrence model is empirically tested using quantitative data, and comparison is discussed using qualitative data collected in both countries.

Findings
– The findings provide solid understanding of customers’ behaviours towards online financial transactions and fraud occurrence internationally. As the main implication, customer education is proposed to benefit financial organisations in both countries. According to the data collection process and the data analysis results, individual customers are aware of banking policies and practices to some extent. Particularly in China, customers’ satisfaction level is relatively lower and service quality is not reasonable in most circumstances.

Research limitations/implications
– The research experiences gained from this study suggest a number of areas for future research, particularly the under-researched area of fraud. Rather than approaching the research questions through individuals, there would be much value in working with merchants and financial organisations that are dealing with financial transactions and fraud on a daily basis.

Originality/value
– By combining three approaches (demographic factors, financial activities and IT usage), this study is trying to develop a comprehensive and statistical understanding of online fraud occurrences.
Gender and the use of external business advice: a Swedish study
Authors: Yazdanfar Darush , Abbasian Saeid 
Published: February 2015

Purpose– The aim of this study is to examine whether there are significant differences between female and male entrepreneurs’ use of consultation during business start-ups.Design/methodology/approach– Using several statistical tools, including ANOVA and seemingly unrelated regressions, empirical analyses are conducted on a unique and firm-level panel database of 837 female- and 1926 male-owned active small firms.Findings– The results indicate that gender may be an important variable in the use of advice among small business owners in Sweden. Female owners in this study are shown to be more eager than male owners to use external business advice, and do so to a higher extent.Practical implications– One implication of this study is that firms may not be able to use all business advice types simultaneously during their start-up stage, so an ordered list of consultancy services would help them prioritize and adjust their needs accordingly. Because the use of business advice is context-based, the findings of this study may not be generalized to firms in other countries. This paper shows some gender-based attributes/features relating to the use of business advice, which need to be better integrated into policymaking for the future assistance of small businesses.Originality/value– This article focuses on an important issue and is unique partly because few studies have examined the relationship between gender and external business advice. By explicitly and empirically examining this issue, this article makes a contribution to the small- and medium-sized enterprises’ literature.